title: Fibrin glue for mesh fixation in laparoscopic transabdominal preperitoneal (TAPP) hernia repair: indications, technique, and outcomes.
abstract: BACKGROUND
  The efficacy and safety of prosthesis fixation were studied by means of fibrin glue (Tissucol, Baxter Healthcare) during laparoscopic transabdominal preperitoneal (TAPP) treatment of inguinal and femoral hernias.
  
  
  METHODS
  Between September 2001 and December 2004, fibrin glue was used for mesh fixation during TAPP.
  
  
  RESULTS
  In this study, 320 hernias were treated for 230 patients (225 men and 5 women) with an average age of 45 years (range, 20-75 years). No perioperative complications were observed. After an average follow-up period of 26 months (range, 1-40 months), the only postoperative complications observed were six seromas (1.8%) and one trocar-site hematoma (0.3%). The mean operating time was 30 min for unilateral hernias and 50 min for bilateral hernias, whether primary or recurrent. Patients usually were discharged the day after surgery and returned to work after 5 days.
  
  
  CONCLUSIONS
  The authors' experience demonstrates that fibrin glue (Tissucol) is an effective method for mesh fixation during TAPP.
authors.affiliation: Department of Surgery, Center of Laparoscopic and Minimally Invasive Surgery, San Gerardo Hospital, Monza, Italy.
authors.forename: S
authors.initials: S
authors.lastname: Olmi
authors.forename: L
authors.initials: L
authors.lastname: Erba
authors.forename: A
authors.initials: A
authors.lastname: Bertolini
authors.forename: A
authors.initials: A
authors.lastname: Scaini
authors.forename: E
authors.initials: E
authors.lastname: Croce
mesh_terms: D000287:Administration, Topical; D000328:Adult; D000368:Aged; D005260:Female; D015718:Fibrin Tissue Adhesive / Q000008:administration & dosage*; D005500:Follow-Up Studies; D006552:Hernia, Inguinal / Q000601:surgery*; D006801:Humans; D010535:Laparoscopy / Q000379:methods*; D008297:Male; D008875:Middle Aged; D010537:Peritoneum / Q000601:surgery*; D011474:Prosthesis Design; D019919:Prosthesis Implantation / Q000379:methods*; D012189:Retrospective Studies; D013526:Surgical Mesh; D014014:Tissue Adhesives / Q000008:administration & dosage*; D016896:Treatment Outcome
chemical_list: D015718:Fibrin Tissue Adhesive; D014014:Tissue Adhesives