title: EUS-guided mucosectomy for gastrointestinal cancer.
abstract: BACKGROUND
  the only way of improving prognosis and survival in gastrointestinal cancer is early diagnosis, with intramucosal localization as confirmed by endoscopic ultrasonography (EUS) or 20-MHz miniprobes (MPs) (T1) being most appropriate. Endoscopic mucosal resection (EMR) has proven effective in the treatment of this sort of lesions.
  
  
  METHODS
  in a group (18 cases) with 15 cases of superficial gastrointestinal cancer and 3 cases of severe gastric dysplasia, 9 cases (3 esophageal, 4 gastric, 2 rectal) underwent a classic EMR following EUS or a 7.5- and 20-MHz miniprobe exploration.
  
  
  RESULTS
  ultrasonographic studies showed a T1 in all but one esophageal case (Tis), and in both gastric dysplasias, with no changed layer structure being demonstrated in the latter (T0). No complications arose with classic EMR, and all 9 patients are alive and free from local or metastatic recurrence, except for one esophageal case, which recurred distally to the esophageal lesion (metachronous).
  
  
  CONCLUSIONS
  echoendoscopically-assisted EMR is a safe, effective technique in the endoscopic management of superficial gastrointestinal (esophageal, gastric, colorectal) cancer. Recurrence most likely depends upon cancer multiplicity.
authors.affiliation: Echoendoscopy Unit, Centro Médico Delfos., A Coruña, Spain.
authors.forename: J M
authors.initials: JM
authors.lastname: Miquel
authors.forename: R
authors.initials: R
authors.lastname: Abad
authors.forename: J
authors.initials: J
authors.lastname: Souto
authors.forename: R
authors.initials: R
authors.lastname: Fabra
authors.forename: M
authors.initials: M
authors.lastname: Vila
authors.forename: D
authors.initials: D
authors.lastname: Bargalló
authors.forename: J L
authors.initials: JL
authors.lastname: Vázquez-Iglesia
authors.forename: M J
authors.initials: MJ
authors.lastname: Varas Lorenzo
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D013505:Digestive System Surgical Procedures; D016145:Endoscopy, Digestive System; D019160:Endosonography; D005260:Female; D005753:Gastric Mucosa / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D005770:Gastrointestinal Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D006801:Humans; D007413:Intestinal Mucosa / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D016896:Treatment Outcome