Introversion associated with large differences between screening blood pressure and home blood pressure measurement: The Ohasama study.
OBJECTIVE
To explore the effect of personality on screening blood pressures measured in clinical settings and home blood pressure measurements.


METHODS
From 1997 to 1999, 699 participants underwent screening and home blood pressure measurements and completed the Japanese version of the short-form Eysenck personality questionnaire. An increased screening blood pressure was defined as screening blood pressure > or = 140/90 mmHg and an increased home blood pressure was defined as home blood pressure > or = 135/85 mmHg.


RESULTS
Participants with lower extroversion scores (i.e., introversion) showed a greater difference between screening and home systolic blood pressure. The association between introversion and differences was statistically significant, even after adjustment for other possible factors (younger age, female, wide screening pulse pressure, never smoked, and no antihypertensive medication). The adjusted means of SBP differences were 7.3 and 4.4 mmHg among the lowest and highest extroversion quartiles, respectively (P for trend = 0.02). Other personality scores (psychoticism or neuroticism) were not associated with screening and home blood pressure differences. The incorporation of an extroversion score in the basic model consisting of the above factors that affected the difference between screening and home blood pressure slightly improved the prediction of a high home blood pressure. The area under the receiver operating characteristic curve increased by 0.037 among participants with high screening blood pressure and 0.006 for those with normal screening blood pressure compared with the basic model.


CONCLUSIONS
Physicians may need to be aware of 'introverted' patients who have high blood pressure in clinic settings, because they have the potential for 'white-coat' hypertension.
Hozawa
Atsushi
A
Department of Health Science, Shiga University of Medical Science, Shiga, Japan. hozawa-thk@umin.ac.jp
Ohkubo
Takayoshi
T
Obara
Taku
T
Metoki
Hirohito
H
Kikuya
Masahiro
M
Asayama
Kei
K
Totsune
Kazuhito
K
Hashimoto
Junichiro
J
Hoshi
Haruhisa
H
Arai
Yumiko
Y
Satoh
Hiroshi
H
Hosokawa
Toru
T
Imai
Yutaka
Y
D000368:Aged; D001794:Blood Pressure / Q000502:physiology; D018660:Blood Pressure Monitoring, Ambulatory / Q000379:methods / Q000523:psychology*; D005260:Female; D006801:Humans; D006973:Hypertension / Q000175:diagnosis* / Q000523:psychology*; D007439:Introversion, Psychological; D007564:Japan; D008297:Male; D008403:Mass Screening / Q000379:methods; D008875:Middle Aged; D010817:Physician-Patient Relations; D011237:Predictive Value of Tests; D012372:ROC Curve