title: Metastatic non-small-cell lung carcinoma successfully treated with pre-operative chemotherapy and bilateral adrenalectomy.
abstract: Metastatic non-small-cell lung cancer is a common condition with a dismal prognosis. Although palliative chemotherapy improves survival and quality of life, nearly all patients die of progressive disease. Metastatic involvement of adrenal glands is not rare, but usually reflects widespread dissemination. Selected patients with single adrenal metastasis may be cured with surgery, although the level of evidence comes from single cases reports and short retrospective series. Here we report a patient with bilateral adrenal metastases from previously resected non-small-cell lung cancer, who remains free of disease four years after pre-operative chemotherapy and bilateral adrenalectomy.
authors.affiliation: Department of Medical Oncology, Hospital de Cruces, Osakidtza, Basque Country, Spain. amunoz@hcru.osakidetza.net
authors.forename: Alberto
authors.initials: A
authors.lastname: Muñoz
authors.forename: Guillermo
authors.initials: G
authors.lastname: López-Vivanco
authors.forename: Joan-Manel
authors.initials: JM
authors.lastname: Mañé
authors.forename: Ricardo
authors.initials: R
authors.lastname: Fernández
authors.forename: Javier
authors.initials: J
authors.lastname: Díaz-Aguirregoitia
authors.forename: Mónica
authors.initials: M
authors.lastname: Saiz
authors.forename: Ramón
authors.initials: R
authors.lastname: Barceló
mesh_terms: D000310:Adrenal Gland Neoplasms / Q000188:drug therapy* / Q000556:secondary* / Q000601:surgery; D000315:Adrenalectomy; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D002289:Carcinoma, Non-Small-Cell Lung / Q000556:secondary* / Q000601:surgery; D002945:Cisplatin / Q000008:administration & dosage; D003131:Combined Modality Therapy; D003841:Deoxycytidine / Q000008:administration & dosage / Q000031:analogs & derivatives; D004334:Drug Administration Schedule; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D011013:Pneumonectomy; D013156:Splenectomy; D000093542:Gemcitabine
chemical_list: D003841:Deoxycytidine; D002945:Cisplatin; D000093542:Gemcitabine