title: Effect of an iron mouthrinse on enamel and dentine erosion subjected or not to abrasion: an in situ/ex vivo study.
abstract: OBJECTIVE
  This in situ/ex vivo study evaluated whether a rinse with an iron solution could reduce wear and the percentage of microhardness change of human enamel and dentine submitted to erosion followed by brushing after 1 or 30min.
  
  
  METHODS
  During 2 experimental 5-day crossover phases (wash-out period of 10 days), 10 volunteers wore intraoral palatal devices, with 12 specimens (6 of enamel and 6 of dentine) arranged in 3 horizontal rows (4 specimens each). In one phase, the volunteers immersed the device for 5min in 150mL of cola drink, 4 times a day. Immediately after immersion, no treatment was performed in one row. The other row was brushed after 1min using a fluoride dentifrice and the device was replaced into mouth. After 30min, the remaining row was brushed. In the other phase, the procedures were repeated, but after immersion the volunteers rinsed for 1min with 10mL of a 10mM ferrous sulphate solution. Changes in surface microhardness (%SMH) and wear (profilometry) of enamel and dentine were measured. Data were tested using ANOVA and Tukey's tests (p<0.05).
  
  
  RESULTS
  The enamel presented more wear than dentine, under all experimental conditions. The iron solution caused a significant reduction on the %SMH in enamel, and a significant reduction on the wear in dentine, regardless the other conditions.
  
  
  CONCLUSIONS
  Rinsing with an iron solution after an erosive attack, followed or not by an abrasive episode, may be a viable alternative to reduce the loss of dental structure.
authors.affiliation: Department of Pediatric Dentistry, Orthodontics and Public Health, Bauru Dental School, University of São Paulo, Al. Octávio Pinheiro Brisolla, 9-75 Bauru, SP 17012-901, Brazil.
authors.forename: S H C
authors.initials: SH
authors.lastname: Sales-Peres
authors.forename: J P
authors.initials: JP
authors.lastname: Pessan
authors.forename: M A R
authors.initials: MA
authors.lastname: Buzalaf
mesh_terms: D000328:Adult; D002253:Carbonated Beverages / Q000009:adverse effects; D018592:Cross-Over Studies; D003743:Dental Enamel / Q000187:drug effects*; D003747:Dental Enamel Solubility / Q000187:drug effects; D003804:Dentin / Q000187:drug effects*; D005260:Female; D005296:Ferrous Compounds / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D014072:Tooth Abrasion / Q000209:etiology / Q000517:prevention & control; D017001:Tooth Demineralization / Q000139:chemically induced / Q000517:prevention & control*; D014077:Tooth Erosion / Q000209:etiology / Q000517:prevention & control; D014099:Toothbrushing / Q000009:adverse effects
chemical_list: D005296:Ferrous Compounds; C020748:ferrous sulfate