FMRI adaptation reveals separate mechanisms for first-order and second-order motion.
A key unresolved debate in human vision concerns whether we have two different low-level mechanisms for encoding image motion. Separate neural mechanisms have been suggested for first-order (luminance modulation) and second-order (e.g., contrast modulation) motion in the retinal image but a single mechanism could handle both. Human functional magnetic resonance imaging (fMRI) has not so far convincingly revealed separate anatomical substrates. To examine whether two separate but co-localized mechanisms might exist, we used the technique of fast fMRI adaptation. We found direction-selective adaptation independently for each type of motion in the motion area V5/MT+ of the human brain. However, there was a total absence of cross-adaptation between first-order and second-order motion stimuli. This was true in both of the two subcomponents of MT+ (MT and MST) and similar results were found in V3A. This pattern of adaptation was consistent with psychophysical measurements of detection thresholds in similar stimulus sequences. The results provide strong evidence for separate neural populations that are responsible for detecting first- and second-order motion.
Ashida
Hiroshi
H
Graduate School of Letters, Kyoto University, Kyoto 606 8501, Japan. ashida@bun.kyoto-u.ac.jp
Lingnau
Angelika
A
Wall
Matthew B
MB
Smith
Andrew T
AT
D000222:Adaptation, Physiological / Q000502:physiology; D000328:Adult; D001931:Brain Mapping; D003627:Data Interpretation, Statistical; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009039:Motion Perception / Q000502:physiology*; D010100:Oxygen / Q000097:blood; D010775:Photic Stimulation; D011601:Psychophysics; D012160:Retina / Q000502:physiology; D014793:Visual Cortex / Q000502:physiology
D010100:Oxygen