[Determination of total organic acids and salicylic acid in extract of Radix isatidis].
OBJECTIVE
To develop a quantitative method for determination of the total organic acids and salicyclic acid in the extract of Radix Isatidis.


METHODS
The total organic acids were determined by acid-base titration and the salicylic acid was determined by HPLC.


RESULTS
It was shown that contents of total organic acids and salicylic acid in the extract of Radix Isatidis were 13.0% and 0.22%, respectively.


CONCLUSIONS
The method can control the quality of this extract effectively and accurately.
Ma
Li
L
302 Hospital of PLA and PLA Institute of Chinese Materia Medica, Beijing 100039, China.
Tang
Jian-yuan
JY
Lu
Zu-lun
ZL
Liao
Qing-wen
QW
Xiao
Xiao-he
XH
Zhao
Xiang-jun
XJ
Jin
Cheng
C
D002264:Carboxylic Acids / Q000032:analysis*; D002851:Chromatography, High Pressure Liquid / Q000379:methods; D004365:Drugs, Chinese Herbal / Q000737:chemistry* / Q000302:isolation & purification; D031219:Isatis / Q000737:chemistry*; D018517:Plant Roots / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D011786:Quality Control; D020156:Salicylic Acid / Q000032:analysis*; D013678:Technology, Pharmaceutical
D002264:Carboxylic Acids; D004365:Drugs, Chinese Herbal; D020156:Salicylic Acid