Controlling a recognition-mediated reaction using a pH switch.
The selective recognition-mediated reaction between a nitrone bearing a urea recognition site and a maleimide bearing a proton switchable recognition site can be turned 'on' and 'off' by the addition of base and acid respectively.
Turega
Simon M
SM
EaStCHEM and Centre for Biomolecular Sciences, School of Chemistry, University of St Andrews, North Haugh, St Andrews, Fife, UK.
Philp
Douglas
D
D006863:Hydrogen-Ion Concentration; D008301:Maleimides / Q000737:chemistry*; D015394:Molecular Structure; D009589:Nitrogen Oxides / Q000737:chemistry*; D013997:Time Factors; D014508:Urea / Q000737:chemistry*
D008301:Maleimides; D009589:Nitrogen Oxides; C015388:nitrones; C043592:maleimide; D014508:Urea