title: A DNA chip-based spoligotyping method for the strain identification of Mycobacterium tuberculosis isolates.
abstract: The clinical efficacy of a spoligotyping method for discriminating Mycobacterium tuberculosis strains was evaluated. Among the strains other than Beijing or Beijing like family, 30 different spoligotypes out of 39 strains were produced, which included 4 strains not having IS6110 sequence. The oligonucleotide chip-based spoligotyping technique is useful for early screening and detection of clonal proximity of M. tuberculosis isolates.
authors.affiliation: Department of Laboratory Medicine, School of Medicine, Pusan National University, Seo-Gu Ami-Dong 1-10, Busan 602-739, Republic of Korea.
authors.forename: Eun Ju
authors.initials: EJ
authors.lastname: Song
authors.forename: Hae Jin
authors.initials: HJ
authors.lastname: Jeong
authors.forename: Sun Min
authors.initials: SM
authors.lastname: Lee
authors.forename: Cheol Min
authors.initials: CM
authors.lastname: Kim
authors.forename: Eun Sil
authors.initials: ES
authors.lastname: Song
authors.forename: Young Kil
authors.initials: YK
authors.lastname: Park
authors.forename: Gill-Han
authors.initials: GH
authors.lastname: Bai
authors.forename: Eun Yup
authors.initials: EY
authors.lastname: Lee
authors.forename: Chulhun L
authors.initials: CL
authors.lastname: Chang
mesh_terms: D016172:DNA Fingerprinting / Q000379:methods*; D004269:DNA, Bacterial / Q000737:chemistry / Q000235:genetics; D021901:DNA, Intergenic / Q000737:chemistry / Q000235:genetics; D006801:Humans; D009169:Mycobacterium tuberculosis / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification; D020411:Oligonucleotide Array Sequence Analysis / Q000379:methods*; D014376:Tuberculosis / Q000382:microbiology*
chemical_list: D004269:DNA, Bacterial; D021901:DNA, Intergenic