LRRK2 mutations on Crete: R1441H associated with PD evolving to PSP.
Spanaki
Cleanthe
C
Department of Neurology, University of Crete, Medical School, Heraklion, Crete, Greece.
Latsoudis
Helen
H
Plaitakis
Andreas
A
D017668:Age of Onset; D000368:Aged; D000369:Aged, 80 and over; D001120:Arginine; D015331:Cohort Studies; D003704:Dementia / Q000209:etiology; D018450:Disease Progression; D005260:Female; D020022:Genetic Predisposition to Disease; D006115:Greece; D006639:Histidine; D006801:Humans; D000071158:Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; D008297:Male; D008875:Middle Aged; D009154:Mutation; D010300:Parkinson Disease / Q000453:epidemiology / Q000235:genetics* / Q000503:physiopathology / Q000523:psychology; D010375:Pedigree; D017346:Protein Serine-Threonine Kinases / Q000235:genetics*; D013494:Supranuclear Palsy, Progressive / Q000453:epidemiology / Q000235:genetics*
D006639:Histidine; D001120:Arginine; C495280:LRRK2 protein, human; D000071158:Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; D017346:Protein Serine-Threonine Kinases