[Clinical presentation of ST-elevation acute coronary syndrome in the course of intoxication with megadose of rifampicin. A case report].
We present a case of 29-year-old male, with coronary artery disease in mother's history, after suicidal poisoning with 30 g of rifampicin, who presented severe chest pain, ST elevations in ECG, low values of blood pressure and elevated troponin I. Echocardiography revealed generalised hypokinesia, and depressed contractility--left ventricle ejection fraction was 7%. Urgent coronary angiography has shown normal epicardial arteries with slow contrast inflow. The toxic properties of rifampicin as well as hypotension due to dehydration are considered reasons of symptoms in the presented case.
Rechciński
Tomasz
T
II Katedra i Klinika Kardiologii UM, Szpital im. Władysława Biegańskiego, ul. Kniaziewicza 1/5, 91-347 Łódź. Tomasz.2336843@pharmanet.com.pl
Plewka
Michał
M
Kurpesa
Małgorzata
M
Kidawa
Michał
M
Peruga
Zbigniew
Z
Łopaciński
Bogdan
B
Kołaciński
Zbigniew
Z
Krzemińska-Pakuła
Maria
M
D000208:Acute Disease; D000328:Adult; D000789:Angina, Unstable / Q000139:chemically induced* / Q000175:diagnosis; D002303:Cardiac Output, Low / Q000139:chemically induced / Q000175:diagnosis; D002637:Chest Pain / Q000097:blood / Q000139:chemically induced; D017023:Coronary Angiography; D003937:Diagnosis, Differential; D062787:Drug Overdose; D004562:Electrocardiography; D006801:Humans; D008297:Male; D012293:Rifampin / Q000506:poisoning*; D013406:Suicide, Attempted; D016896:Treatment Outcome; D019210:Troponin I / Q000097:blood / Q000187:drug effects
D019210:Troponin I; D012293:Rifampin