title: Giant intracranial aneurysms: endovascular challenges.
abstract: The treatment of giant aneurysms remains a formidable challenge for endovascular and surgical strategies. The use of endovascular techniques in a deconstructive (e.g., parent vessel occlusion) and reconstructive (e.g., stent coiling) methodology is reviewed. The results of endovascular coiling as a primary therapy for giant aneurysm occlusion have been disappointing. Hunterian strategies have had more success in published series, but recent developments in coil, glue, and stent technology show great promise in allowing parent vessel reconstruction as a primary endovascular target, with acceptable morbidity, mortality, and durability. A literature review of giant aneurysm endovascular treatment strategies was undertaken after 1994, when Guglielmi detachable coils were approved by the Food and Drug Administration. Where possible, follow-up, durability, and occlusion rates are also reviewed.
authors.affiliation: Department of Neurological Surgery, Northwestern University, Feinberg School of Medicine, Chicago, Illinois 60611, USA.
authors.forename: Richard J
authors.initials: RJ
authors.lastname: Parkinson
authors.forename: Christopher S
authors.initials: CS
authors.lastname: Eddleman
authors.forename: H Hunt
authors.initials: HH
authors.lastname: Batjer
authors.forename: Bernard R
authors.initials: BR
authors.lastname: Bendok
mesh_terms: D001807:Blood Vessel Prosthesis / Q000639:trends*; D002404:Catheterization / Q000639:trends*; D004621:Embolization, Therapeutic / Q000639:trends*; D006801:Humans; D002532:Intracranial Aneurysm / Q000628:therapy*; D019635:Neurosurgical Procedures / Q000639:trends*; D019651:Plastic Surgery Procedures / Q000639:trends; D015607:Stents; D016896:Treatment Outcome; D014656:Vascular Surgical Procedures / Q000639:trends*