Pathomorphological peculiarities of damage to hair cells of the organ of corti in experimental sensorineural hearing loss.
Pathomorphology of the organ of Corti was studied on models of acute and chronic sensorineural damage to the acoustic analyzer. Peculiarities of hair cell degeneration, necrosis, and apoptosis in the organ were studied by light and scanning electron microscopy. The type of pathomorphological substrate in abnormalities of the organ of Corti depends on the intensity of the destructive exposure, but not on the nature of otopathological factors.
Zhuravskii
S G
SG
Laboratory of Hearing and Speech, Laboratory of Pathomorphology, I. P. Pavlov State Medical University, St. Petersburg. sjour@spmu.rssi.ru
Borodulin
V G
VG
Tomson
V V
VV
Lopotko
A I
AI
D000818:Animals; D006198:Hair Cells, Auditory / Q000473:pathology* / Q000648:ultrastructure; D006319:Hearing Loss, Sensorineural / Q000473:pathology*; D008297:Male; D008855:Microscopy, Electron, Scanning; D051381:Rats; D017208:Rats, Wistar