[Study on antioxidant activity of pigment of Lycium ruthenicum].
OBJECTIVE
To elvaulate the antioxidant activity of the pigment of Lycium ruthenicum.


METHODS
The antioxidant activities were measured by the effects of the reducing ability, scavenging DPPH. H2O2-induced hemolysis of mice erythrocyte, serum resistance of reactive oxygen species, content of MDA in liver tissue, and swelling effect of mitochondria in liver tissue.


RESULTS
The pigment of L. ruthenicum could scaveng DPPH* remarkably with IC50 0.164 mg x mL(-1), inhibitte hemolysis of mice erythrocyte evidently with IC50 0.112 mg x mL(-1). The resistant of reactive oxygen species was enhanced by the tested substances, simultanously. The concentration of MDA of peroxidation of lipid in mice liver could be reduced, and the swelling of mice liver mitochondria alse be restrained.


CONCLUSIONS
The pigment of L. ruthenicum has antioxidant activity in tested concentration.
Li
Jin
J
School of Life Science, East China Normal University, Shanghai 200062, China.
Qu
Wei-Jing
WJ
Zhang
Su-Jun
SJ
Lv
Hai-Ying
HY
D000818:Animals; D000975:Antioxidants / Q000494:pharmacology*; D001713:Biphenyl Compounds / Q000378:metabolism; D004912:Erythrocytes / Q000187:drug effects; D016166:Free Radical Scavengers / Q000494:pharmacology; D006461:Hemolysis / Q000187:drug effects; D006834:Hydrazines / Q000378:metabolism; D015227:Lipid Peroxidation / Q000187:drug effects; D008099:Liver / Q000378:metabolism; D032305:Lycium / Q000737:chemistry; D008315:Malondialdehyde / Q000378:metabolism; D051379:Mice; D008930:Mitochondria, Liver / Q000473:pathology; D008933:Mitochondrial Swelling / Q000187:drug effects; D010636:Phenols / Q000302:isolation & purification / Q000494:pharmacology; D010851:Picrates; D010860:Pigments, Biological / Q000302:isolation & purification / Q000494:pharmacology*; D010946:Plants, Medicinal / Q000737:chemistry; D017382:Reactive Oxygen Species
D000975:Antioxidants; D001713:Biphenyl Compounds; D016166:Free Radical Scavengers; D006834:Hydrazines; D010636:Phenols; D010851:Picrates; D010860:Pigments, Biological; D017382:Reactive Oxygen Species; D008315:Malondialdehyde; C004931:1,1-diphenyl-2-picrylhydrazyl