Fatal encephalopathy and renal failure caused by diethylene glycol poisoning.
Diethylene glycol poisoning results in multiorgan dysfunction and requires a high index of suspicion for diagnosis. We report 11 patients of diethylene glycol poisoning, all of whom had renal failure and severe encephalopathy. The diagnosis was established by the presence of diethylene glycol in the paracetamol elixir consumed by these children; the amount of which ranged from 2.3 to 23% w/W. Consumption of large amount of toxin resulted in severe encephalopathy and high mortality in these children.
Hari
Pankaj
P
Department of Pediatrics, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110029, India. pankajhari@hotmail.com
Jain
Yogesh
Y
Kabra
Sushil Kumar
SK
D000082:Acetaminophen; D058186:Acute Kidney Injury / Q000139:chemically induced*; D002675:Child, Preschool; D004340:Drug Contamination; D005026:Ethylene Glycols / Q000506:poisoning*; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007194:India / Q000453:epidemiology; D007223:Infant; D008297:Male; D020258:Neurotoxicity Syndromes
D005026:Ethylene Glycols; D000082:Acetaminophen; C013484:diethylene glycol