[Effects of different reconstruction methods in treatment of avulsion of ureteral mucosa: experiment with dogs].
OBJECTIVE
To investigate the curative effects of different reconstruction methods in the treatment of avulsion of ureteral mucosa.


METHODS
Twenty adult dogs were randomly divided into 4 equal groups: Group III (control group in which the ureter was incised and a ureteral stent was placed therein), Group II (the ureter was incised and a ureteral mucosal avulsion about 5 cm in length was created and the avulsed mucosa was replaced to the original position and a ureteral stent was placed in addition), Group III (a piece of bladder mucosa was incised and grafted to the avulsed ureter mucosa and a ureteral stent was placed in addition), and Group IV (a tubularized peritoneal free graft and a ureteral stent were placed in the avulsed ureter). Ten weeks later intravenous pyelography (IVP) was conducted to observe the images of ureter. Then the dogs were killed and pathological examination of the reconstructed ureter was conducted.


RESULTS
IVP showed atresia and stenosis in all control group dogs. No obvious stenosis was observed in Groups II and IV. Pathological examination showed that the newly grown mucosa was similar to the normal ureter structure in Groups II and IV. In Group III one dog died, slight distension of ureter superior to the reconstructed part was found in 2 dogs, and no obvious stenosis was observed in 3 dogs.


CONCLUSIONS
Orthotopic replacement and tabularized peritoneal free grafting with placement of ureter stent are effective in treatment of avulsion of ureter mucosa. Bladder mucosa can be used as selectable material.
Xia
Shu-jie
SJ
Department of Urology, First Affiliated People's Hospital of Shanghai, Jiaotong University, Shanghai 200080, China. xsj@citiz.net
Lü
Bo-dong
BD
Jing
Yi-feng
YF
Sun
Hong-bin
HB
Tang
Xiao-da
XD
D000818:Animals; D004285:Dogs; D009092:Mucous Membrane / Q000473:pathology; D011897:Random Allocation; D019651:Plastic Surgery Procedures / Q000379:methods*; D014515:Ureteral Diseases / Q000473:pathology / Q000601:surgery*; D001743:Urinary Bladder