title: Laparoscopic left lateral sectionectomy in living donors: safety and reproducibility of the technique in a single center.
abstract: OBJECTIVE
  Left lateral sectionectomy for liver transplantation in children performed through laparoscopy is an innovative procedure that was developed by considering our acquired experience in both laparoscopic liver resection and graft harvesting in living donors. The main goal was to minimize donor morbidity while preserving the abdominal wall. Herein, we report the technical feasibility and reproducibility, and compared it with open liver resection (OLR).
  
  
  METHODS
  Sixteen successive donors underwent a laparoscopic liver resection (LLR) from 2001 to 2005. They were compared with 14 other donors who underwent a standard open liver resection (OLR) during a first period (1998-2004). First, this report describes the technical features of laparoscopic resection. Second, perioperative morbidity and graft characteristics were compared according to the use or not of the laparoscopic approach.
  
  
  RESULTS
  Laparoscopic harvesting was successfully performed in 15 of 16 cases in an intention-to-treat basis. One conversion was required to ensure the quality of the laparoscopic repair of a left portal vein injury occurring during the pedicle dissection. No specific complication related to laparoscopy was observed. As compared with OLR, the operation was longer (320 +/- 67 vs. 244 +/- 55 minutes, P < 0.005). The blood loss was significantly lower in the LLR group (18.7 +/- 44.2 vs. 199.2 +/- 185.4 mL, P < 0.005). The morbidity rate was similar in both groups (18.7% in LLR vs. 35.7% in OLR). One donor in the LLR group experienced a bile leak treated by redo laparoscopy. Grafts were anatomically similar irrespective of the use of laparoscopy. The duration of hospital stay and use of self-infused morphine pump was not different between the 2 groups.
  
  
  CONCLUSIONS
  Left lateral section harvesting by laparoscopy is a safe and reproducible procedure, allowing to obtain similar grafts as compared with laparotomy and can therefore be recommended to transplant centers that have previous experience in laparoscopic liver resection.
authors.affiliation: Service de chirurgie, Hôpital Cochin, Assistance Publique-Hôpitaux de Paris, Université Paris-Descartes, France. olivier.soubrane@cch.aphp.fr
authors.forename: Olivier
authors.initials: O
authors.lastname: Soubrane
authors.forename: Daniel
authors.initials: D
authors.lastname: Cherqui
authors.forename: Olivier
authors.initials: O
authors.lastname: Scatton
authors.forename: Fabien
authors.initials: F
authors.lastname: Stenard
authors.forename: Denis
authors.initials: D
authors.lastname: Bernard
authors.forename: Sophie
authors.initials: S
authors.lastname: Branchereau
authors.forename: Hélène
authors.initials: H
authors.lastname: Martelli
authors.forename: Frédéric
authors.initials: F
authors.lastname: Gauthier
mesh_terms: D000328:Adult; D005240:Feasibility Studies; D005260:Female; D005500:Follow-Up Studies; D006085:Graft Survival; D006498:Hepatectomy / Q000379:methods*; D006801:Humans; D010535:Laparoscopy; D008107:Liver Diseases / Q000601:surgery*; D016031:Liver Transplantation / Q000379:methods*; D019520:Living Donors; D008297:Male; D015203:Reproducibility of Results; D012189:Retrospective Studies; D020858:Tissue and Organ Harvesting / Q000379:methods*