[Hungry bone syndrome related to hyperthyroidism].
Hungry bone syndrome is a common clinical entity which is accompanying of hypocalcemia, hypomagnesemia, and hipophosphatemia, results from an increase in bone formation. It is related to a pathological scenario which causes an imbalance between osteoclast-mediated bone resorption and osteoblast-mediates bone formation, favouring the latter. Its classic presentation occurs after parathyroidectomy in hyperparathyroydism's patients. Its clinical features are largely due to plasmatic calcium levels reduction. Hungry bone syndrome is frequent in hyperparathyroid's patients who have development bone disease before surgery. Even less frequent, it has also been described after thyroydectomy in patients with hyperthyroidism. We hereby report a case of hungry bone syndrome in one patient who suffers a Graves' disease. Then, we will provide a brief review of pathogenesis and therapeutic features.
Moure Rodríguez
M D
MD
Servicio de Endocrinología y Nutrición, Hospital Universitario de La Princesa, Madrid.
Luque-Ramírez
M
M
López Gallardo
G
G
López Iglesias
M
M
Gómez-Pan
A
A
D000328:Adult; D001774:Blood Chemical Analysis; D050071:Bone Density Conservation Agents / Q000627:therapeutic use; D002117:Calcitriol / Q000627:therapeutic use; D002125:Calcium Gluconate / Q000627:therapeutic use; D005260:Female; D006801:Humans; D006980:Hyperthyroidism / Q000150:complications* / Q000175:diagnosis / Q000601:surgery; D006996:Hypocalcemia / Q000097:blood / Q000188:drug therapy / Q000209:etiology*; D007011:Hypoparathyroidism / Q000097:blood / Q000188:drug therapy / Q000209:etiology*; D008275:Magnesium Deficiency / Q000097:blood / Q000188:drug therapy / Q000209:etiology; D011183:Postoperative Complications; D013965:Thyroidectomy / Q000009:adverse effects*; D016896:Treatment Outcome
D050071:Bone Density Conservation Agents; D002117:Calcitriol; D002125:Calcium Gluconate