Reconstruction of cavernous nerves by nerve grafts to restore potency: contemporary review of technical principles and basic anatomy.
OBJECTIVE
The review discusses the efficacy of reconstructing the neurovascular bundle to regain sexual function if nerve-sparing prostatectomy is unfeasible.


RESULTS
Eleven studies could be found describing the reconstruction of neurovascular bundles. All reconstructive procedures displayed technical inadequacies. The effectiveness of unilateral neurovascular bundle reconstruction remains statistically insignificant when compared with procedures without reconstruction. The efficacy of reconstructing both neurovascular bundles ranges between 0 and 43%. Concerning basic anatomy, the neurovascular bundle contains fibers innervating the cavernous nerves, prostate, rectum, and levator ani muscle. The terms cavernous nerve and neurovascular bundle have often been wrongly considered synonymous. The pelvic splanchnic nerves probably do not join the neurovascular bundle proximal to the bladder/prostate junction but rather at variable distances from 10 to 20 mm distal to it. Therefore, described proximal coaptation sites at the bladder/prostate junction possibly encompass only the hypogastric nerve.


CONCLUSIONS
Modest clinical results are partly due to inadequate surgical techniques and are mainly due to the anatomical and topographical complexity of the cavernous nerves. Contemporary nerve grafting techniques probably do not allow for the regeneration of all cavernous nerves.
Turkof
Edvin
E
Department of Plastic and Reconstructive Surgery, Medical University of Vienna, Waehringer Guertel 18-20, 1090 Vienna, Austria. edvin@turkof.com
Wulkersdorfer
Beatrix
B
Bukaty
Adam
A
D007172:Erectile Dysfunction / Q000503:physiopathology / Q000601:surgery*; D006801:Humans; D008297:Male; D010413:Penis / Q000033:anatomy & histology / Q000294:innervation* / Q000502:physiology* / Q000601:surgery; D010525:Peripheral Nerves / Q000033:anatomy & histology* / Q000601:surgery / Q000637:transplantation*; D011467:Prostate / Q000294:innervation; D012007:Rectum / Q000294:innervation; D013521:Urologic Surgical Procedures, Male / Q000379:methods* / Q000639:trends