title: Successful complete regression of isolated intramedullary spinal cord metastases from epithelial ovarian carcinoma with chemotherapy and radiotherapy.
abstract: Advances in the management of ovarian cancer by use of aggressive surgery and effective platinum-based chemotherapy have prolonged survival; this may have resulted in an alteration of the metastatic pattern of the disease and spread to unusual sites (e.g, CNS) has become more common. Also, with the availability of more sensitive imaging techniques, these tumors are being diagnosed with increasing frequency. Intramedullary spinal cord metastasis is rare. We report one such case treated successfully with chemotherapy and radiotherapy with long-term survival.
authors.affiliation: Department of Medical Oncology, Tata Memorial Hospital, Parel, Mumbai, India.
authors.forename: A
authors.initials: A
authors.lastname: Bakshi
authors.forename: G
authors.initials: G
authors.lastname: Biswas
authors.forename: C
authors.initials: C
authors.lastname: Deshmukh
authors.forename: N
authors.initials: N
authors.lastname: Prasad
authors.forename: R
authors.initials: R
authors.lastname: Nair
authors.forename: P M
authors.initials: PM
authors.lastname: Parikh
mesh_terms: D000284:Administration, Oral; D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D018394:CA-125 Antigen / Q000134:cerebrospinal fluid; D003131:Combined Modality Therapy; D018284:Cystadenocarcinoma, Serous / Q000188:drug therapy / Q000532:radiotherapy; D004334:Drug Administration Schedule; D005047:Etoposide / Q000008:administration & dosage / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008159:Lumbar Vertebrae / Q000000981:diagnostic imaging; D010051:Ovarian Neoplasms / Q000188:drug therapy* / Q000532:radiotherapy*; D011859:Radiography; D012074:Remission Induction / Q000379:methods; D013120:Spinal Cord Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000532:radiotherapy* / Q000556:secondary*
chemical_list: D018394:CA-125 Antigen; D005047:Etoposide