The place and role of serologic methods in detecting Helicobacter pylori infection.
The aim of the study was to determine the place and role of serologic methods in detecting Helicobacter pylori (H. pylori) infection, on the basis of estimated enzyme-linked immunosorbent assay (ELISA) and complement fixation test (CFT) sensitivity and specificity. A total of 549 patients were included in the study. ELISA and CFT as serologic methods were compared with invasive methods (rapid urease test--CLO test, culture, histology). The sensitivity of serologic methods was above 90%, and their specificity was around 80%. Study results confirmed the value, reliability and usefulness of serologic methods in the detection of H. pylori infection.
Marusić
Marinko
M
University Department of Medicine, General Hospital Sveti Duh, Zagreb, Croatia. marinko.marusic1@zg.t-com.hr
Presecki
Vladimir
V
Katicić
Miroslava
M
Dominis
Mara
M
Kalenić
Smilja
S
D000328:Adult; D000907:Antibodies, Bacterial / Q000302:isolation & purification*; D003168:Complement Fixation Tests / Q000379:methods*; D004797:Enzyme-Linked Immunosorbent Assay / Q000379:methods*; D005260:Female; D016481:Helicobacter Infections / Q000175:diagnosis*; D016480:Helicobacter pylori / Q000276:immunology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012680:Sensitivity and Specificity
D000907:Antibodies, Bacterial