title: Stereotactic surgery for subthalamic nucleus stimulation under general anesthesia: a retrospective evaluation of Japanese patients with Parkinson's disease.
abstract: We compared retrospectively the outcome of bilateral subthalamic nucleus (STN) stimulation in 15 patients with Parkinson's disease who underwent the procedure under general anesthesia (GA) with that achieved in 10 patients under local anesthesia (LA). At 3 months postoperatively, all cardinal parkinsonian motor symptoms, evaluated on Unified Parkinson's Disease Rating Scale were significantly improved compared to preoperative baselines in both groups. The administration of GA did not adversely affect postoperative improvements in motor and daily activity scores, except for off-medication bradykinesia. Our results suggest that GA compares favorably with LA in surgical procedure for bilateral STN stimulation.
authors.affiliation: Department of Neurosurgery, Graduate School of Medical Sciences, Kumamoto University, 1-1-1 Honjo, Kumamoto City 860-8556, Kumamoto, Japan. yamadakazu@fc.kuh.kumamoto-u.ac.jp
authors.forename: Kazumichi
authors.initials: K
authors.lastname: Yamada
authors.forename: Satoshi
authors.initials: S
authors.lastname: Goto
authors.forename: Jun-Ichi
authors.initials: J
authors.lastname: Kuratsu
authors.forename: Kazuhito
authors.initials: K
authors.lastname: Matsuzaki
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Tamura
authors.forename: Shinji
authors.initials: S
authors.lastname: Nagahiro
authors.forename: Nagako
authors.initials: N
authors.lastname: Murase
authors.forename: Hideki
authors.initials: H
authors.lastname: Shimazu
authors.forename: Ryuji
authors.initials: R
authors.lastname: Kaji
mesh_terms: D000368:Aged; D000758:Anesthesia / Q000379:methods; D046690:Deep Brain Stimulation / Q000379:methods*; D005260:Female; D006801:Humans; D007564:Japan / Q000208:ethnology; D008297:Male; D008875:Middle Aged; D010300:Parkinson Disease / Q000473:pathology* / Q000601:surgery*; D012189:Retrospective Studies; D013238:Stereotaxic Techniques; D020531:Subthalamic Nucleus / Q000601:surgery*