title: [Effect of flavonoids from Hippophae rhamniodes residues on blood lipoid metabolism and antioxidative activity in climacteric rats].
abstract: OBJECTIVE
  To study the effect of flavonoids from seed residues of Hippophae rhamnoides (FH) on the lipid metabolism and antioxidative activity in climacteric rats.
  
  
  METHODS
  Menopausal rats with aging were used in this experiment. The rats were fed with FH by gastrogavage for 13 weeks. The effect of drug on the lipid metabolism and the antioxidative activity were observed after the rats were killed.
  
  
  RESULTS
  Serum total cholesterol was decreased significantly in rats fed with FH, T-AOC and SOD in serum and liver were significantly higher than those in rats fed with water, and at the same time MDA was lower than that in rats fed with water.
  
  
  CONCLUSIONS
  FH can improve the climacteric rats' lipid metabolism, and enhance the antioxidation in climacteric rats.
authors.affiliation: School of Life Science, East China Normal University, Shanghai.
authors.forename: Xian-yan
authors.initials: XY
authors.lastname: Yang
authors.forename: Wei-jing
authors.initials: WJ
authors.lastname: Qu
authors.forename: Zi-liang
authors.initials: ZL
authors.lastname: Xu
authors.lastname: Miu-Qian
authors.forename: Li-xian
authors.initials: LX
authors.lastname: Zhu
authors.forename: Zhi-min
authors.initials: ZM
authors.lastname: Xu
mesh_terms: D000818:Animals; D000975:Antioxidants / Q000494:pharmacology*; D002784:Cholesterol / Q000097:blood; D002979:Climacteric / Q000097:blood*; D005260:Female; D005419:Flavonoids / Q000302:isolation & purification / Q000494:pharmacology*; D031281:Hippophae / Q000737:chemistry; D050356:Lipid Metabolism / Q000187:drug effects*; D008099:Liver / Q000378:metabolism; D008315:Malondialdehyde / Q000097:blood / Q000378:metabolism; D010946:Plants, Medicinal / Q000737:chemistry; D011897:Random Allocation; D051381:Rats; D017207:Rats, Sprague-Dawley; D012639:Seeds / Q000737:chemistry; D013482:Superoxide Dismutase / Q000097:blood / Q000378:metabolism; D014280:Triglycerides / Q000097:blood
chemical_list: D000975:Antioxidants; D005419:Flavonoids; D014280:Triglycerides; D008315:Malondialdehyde; D002784:Cholesterol; D013482:Superoxide Dismutase