title: Nanobiomaterial applications in orthopedics.
abstract: Advancements in nanobiotechnology are revolutionizing our capability to understand biological intricacies and resolve biological and medical problems by developing subtle biomimetic techniques. Nanocomposites and nanostructured materials are believed to play a pivotal role in orthopedic research since bone itself is a typical example of a nanocomposite. This article reviews current strategies using nanobiomaterials to improve current orthopedic materials and examines their applications in bone tissue engineering. Preliminary investigations support the potential of nanobiomaterials in orthopedic applications; however, significant advancements are necessary to achieve clinical use. Overall, current trends in nanobiotechnology foreshadow a bright future through the use of nanobiomaterials in the orthopedic domain.
authors.affiliation: Department of Bioengineering-MS142, Rice University, PO Box 1892, Houston, Texas 77251-1892, USA.
authors.forename: Elizabeth M
authors.initials: EM
authors.lastname: Christenson
authors.forename: Kristi S
authors.initials: KS
authors.lastname: Anseth
authors.forename: Jeroen J J P
authors.initials: JJ
authors.lastname: van den Beucken
authors.forename: Casey K
authors.initials: CK
authors.lastname: Chan
authors.forename: Batur
authors.initials: B
authors.lastname: Ercan
authors.forename: John A
authors.initials: JA
authors.lastname: Jansen
authors.forename: Cato T
authors.initials: CT
authors.lastname: Laurencin
authors.forename: Wan-Ju
authors.initials: WJ
authors.lastname: Li
authors.forename: Ramalingam
authors.initials: R
authors.lastname: Murugan
authors.forename: Lakshmi S
authors.initials: LS
authors.lastname: Nair
authors.forename: Seeram
authors.initials: S
authors.lastname: Ramakrishna
authors.forename: Rocky S
authors.initials: RS
authors.lastname: Tuan
authors.forename: Thomas J
authors.initials: TJ
authors.lastname: Webster
authors.forename: Antonios G
authors.initials: AG
authors.lastname: Mikos
mesh_terms: D001672:Biocompatible Materials; D040761:Biomimetic Materials; D008855:Microscopy, Electron, Scanning; D053761:Nanocomposites; D036103:Nanotechnology / Q000639:trends*; D009985:Orthopedics / Q000639:trends*; D019736:Prostheses and Implants; D023822:Tissue Engineering / Q000379:methods
chemical_list: D001672:Biocompatible Materials