title: Sequencing the whole genome of infected human cells obtained from diseased patients--a proposed strategy for understanding and overcoming AIDS or other deadest virus-infected diseases.
abstract: As the worry and pandemic about deadest virus such as AIDS and bird flu are intensified, eradical treatments for these virus-infected diseases are in high demand. However we currently know little about the virus involvement in human cells, which results poor therapeutic outcome. We propose that these viruses may penetrate into human genome in diseased cells that may finally result resistance to present applicable therapeutic options. Here proposes a strategy--sequence the whole genome (chromosomal as well as other genetic systems) of infected human cells obtained from diseased patients. This might help us to know greatly more about the consequences of virus infection and achieve biotherapy of specifically targeted in future.
authors.affiliation: School of Life Sciences, Shanghai University, Shanghai 200444, PR China. ludayong@sh163.net <ludayong@sh163.net>
authors.forename: Da-Yong
authors.initials: DY
authors.lastname: Lu
authors.forename: Jian
authors.initials: J
authors.lastname: Ding
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000628:therapy*; D030541:Databases, Genetic; D015894:Genome, Human; D006801:Humans; D008962:Models, Theoretical; D017422:Sequence Analysis, DNA / Q000379:methods*; D045169:Severe Acute Respiratory Syndrome / Q000628:therapy; D014777:Virus Diseases / Q000628:therapy*; D014780:Viruses / Q000378:metabolism