title: Physicochemical modelling of cell signalling pathways.
abstract: Physicochemical modelling of signal transduction links fundamental chemical and physical principles, prior knowledge about regulatory pathways, and experimental data of various types to create powerful tools for formalizing and extending traditional molecular and cellular biology.
authors.affiliation: Center for Cell Decision Processes, Department Biological Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139, USA.
authors.forename: Bree B
authors.initials: BB
authors.lastname: Aldridge
authors.forename: John M
authors.initials: JM
authors.lastname: Burke
authors.forename: Douglas A
authors.initials: DA
authors.lastname: Lauffenburger
authors.forename: Peter K
authors.initials: PK
authors.lastname: Sorger
mesh_terms: D000465:Algorithms; D000818:Animals; D002468:Cell Physiological Phenomena; D006801:Humans; D008954:Models, Biological; D015203:Reproducibility of Results; D015398:Signal Transduction / Q000502:physiology*; D049490:Systems Biology / Q000379:methods