Sarcoid granuloma on black tattoo.
We report the case of a patient with a black and turquoise tattoo who developed sarcoid granulomas on the areas of black pigment. Patch tests showed a positive reaction to nickel, cobalt, and cadmium; spectrophotometric analysis of the black pigment revealed the presence of nickel and cobalt among other metals. Although the pathogenesis of sarcoid granulomas is unknown, it seems that a delayed type hypersensitivity reaction is one of the mechanisms involved.
Morales-Callaghan
Ana María
AM
Department of Dermatology, Clinical Hospital of Valladolid.
Aguilar-Bernier
Miguel
M
Martínez-García
Gerardo
G
Miranda-Romero
Alberto
A
D000328:Adult; D003035:Cobalt / Q000009:adverse effects; D004342:Drug Hypersensitivity; D005260:Female; D006099:Granuloma / Q000139:chemically induced* / Q000276:immunology; D006801:Humans; D006968:Hypersensitivity, Delayed / Q000139:chemically induced*; D009532:Nickel / Q000009:adverse effects; D010858:Pigmentation; D013653:Tattooing / Q000009:adverse effects*
D003035:Cobalt; D009532:Nickel