Bradyarrhythmias during use of the AngioJet system.
The AngioJet system is an effective thrombectomy device, but it may cause chest discomfort and provoke bradyarrhythmias that range from mild bradycardia to asystole. The cause of AngioJet-induced bradyarrhythmia is unknown, although several hypotheses have attempted to explain the phenomenon. Herein several cases will be described, followed by a review of the relevant literature. The literature review suggests that the cause may be related to the effects of the hydrodynamic jets on stretch-activated receptors present on the vascular endothelium, and that pretreatment with gadolinium or streptomycin might prevent activation of these receptors.
Dwarka
Dan
D
Department of Radiology, University of Arizona Health Sciences Center, 1501 North Campbell Avenue, Tucson, AZ 85724-5067, USA.
Schwartz
Stephanie A
SA
Smyth
Stephen H
SH
O'Brien
Michael J
MJ
D000368:Aged; D001919:Bradycardia / Q000209:etiology*; D004487:Edema; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011655:Pulmonary Embolism / Q000601:surgery*; D013119:Spinal Cord Injuries / Q000150:complications / Q000601:surgery; D017131:Thrombectomy / Q000009:adverse effects* / Q000295:instrumentation; D014057:Tomography, X-Ray Computed; D002583:Uterine Cervical Neoplasms / Q000150:complications / Q000473:pathology; D020246:Venous Thrombosis / Q000000981:diagnostic imaging / Q000601:surgery*