title: Brain natriuretic peptide as marker of myocardial iron load in beta-thalassemia.
abstract: Cardiomyopathy due to iron overload represents a frequent life-limiting complication in patients with beta-thalassemia major. We have conducted a study which proved that brain natriuretic peptide plasma levels have high sensitivity and negative predictive value in detecting cardiac hemosiderosis.
authors.forename: Savvas
authors.initials: S
authors.lastname: Nikolidakis
authors.forename: Constantina
authors.initials: C
authors.lastname: Flessa
authors.forename: Nikolaos
authors.initials: N
authors.lastname: Nikolaou
authors.forename: Efstathios D
authors.initials: ED
authors.lastname: Gotsis
authors.forename: Michael
authors.initials: M
authors.lastname: Koutouzis
authors.forename: Eleni
authors.initials: E
authors.lastname: Polyhronaki
authors.forename: Eleni
authors.initials: E
authors.lastname: Vrettou
authors.forename: Zenon S
authors.initials: ZS
authors.lastname: Kyriakides
mesh_terms: D000328:Adult; D015415:Biomarkers / Q000097:blood; D001803:Blood Transfusion / Q000379:methods; D009202:Cardiomyopathies / Q000175:diagnosis* / Q000209:etiology; D015331:Cohort Studies; D005260:Female; D006486:Hemosiderosis / Q000175:diagnosis; D006801:Humans; D019190:Iron Overload / Q000175:diagnosis*; D008297:Male; D020097:Natriuretic Peptide, Brain / Q000097:blood* / Q000378:metabolism; D011237:Predictive Value of Tests; D011336:Probability; D011379:Prognosis; D012680:Sensitivity and Specificity; D012720:Severity of Illness Index; D017086:beta-Thalassemia / Q000150:complications* / Q000175:diagnosis / Q000628:therapy
chemical_list: D015415:Biomarkers; D020097:Natriuretic Peptide, Brain