title: [Transvaginal color doppler ultrasonography and CA125 detection in surveillance of ovarian malignant tumors after operation].
abstract: OBJECTIVE
  Although transvaginal ultrasonography color Doppler flow imaging (TV-CDFI) has been widely applied in ultrasonography diagnosis, studies on TV-CDFI combined with a serum tumor marker CA125 detection in the surveillance of ovarian malignant tumors after operation are few. This study was to evaluate TV-CDFI combined with CA125 detection in the surveillance of ovarian malignant tumors after operation.
  
  
  METHODS
  Sixty-two cases of ovarian malignant tumors after operation were examined by TV-CDFI. The level of CA125 was measured, and the results were evaluated compared with pathologic findings. The diagnostic sensitivity, specificity, and accuracy were calculated.
  
  
  RESULTS
  The diagnostic sensitivity of TV-CDFI or CA125 alone was 84.6% and 65.4%; the specificity was 88.9% and 66.7%; the accuracy was 87.1% and 66.1%. While the diagnostic sensitivity of TV-CDFI combined with CA125 was 92.3%, the specificity was 88.9%, and the accuracy rate rose to 90.3% (P<0.05).
  
  
  CONCLUSIONS
  The diagnostic accuracy for recurrent ovarian malignant tumors is improved by TV-CDFI combined with CA125, which is more helpful in the surveillance of recurrent ovary malignant tumors than TV-CDFI alone.
authors.affiliation: State Key Laboratory of Oncology in South China, Guangzhou, Guangdong, 510060, P. R. China. gzzeng@163.com
authors.forename: Hui
authors.initials: H
authors.lastname: Zeng
authors.forename: Xiao-Qing
authors.initials: XQ
authors.lastname: Pei
authors.forename: Dan-Miao
authors.initials: DM
authors.lastname: Zheng
authors.forename: Yan-Li
authors.initials: YL
authors.lastname: Zhao
authors.forename: Xiao-Yue
authors.initials: XY
authors.lastname: Chen
mesh_terms: D000328:Adult; D000368:Aged; D018394:CA-125 Antigen / Q000097:blood*; D018282:Cystadenocarcinoma, Mucinous / Q000276:immunology / Q000601:surgery; D018284:Cystadenocarcinoma, Serous / Q000276:immunology / Q000601:surgery*; D005260:Female; D006801:Humans; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000000981:diagnostic imaging*; D010051:Ovarian Neoplasms / Q000276:immunology / Q000601:surgery*; D010052:Ovariectomy / Q000379:methods; D012680:Sensitivity and Specificity; D018615:Ultrasonography, Doppler, Color
chemical_list: D018394:CA-125 Antigen