Influence of hydrogen bonds on charge distribution and conformation of L-arginine.
The molecular recognition of adenosine-5'-triphosphate (ATP) with L-arginine (Arg) through hydrogen bonding interactions has been found using 1H NMR, H-H NOESY, acidity titration and fluorescence spectra techniques. The interactions could influence charge distribution in Arg and induce Arg conformational variation. It is realized that Arg conformation change from a partly folded state to an extended state through the rotation of CC single bonds of Arg side chain during the molecular recognition process.
Xian
Liang
L
State Key Laboratory for Oxo Synthesis and Selective Oxidation, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000, China.
Liu
Shuhua
S
Ma
Yanqing
Y
Lu
Gongxuan
G
D000143:Acids / Q000737:chemistry; D000255:Adenosine Triphosphate / Q000737:chemistry*; D001120:Arginine / Q000737:chemistry*; D005453:Fluorescence; D006860:Hydrogen Bonding; D006863:Hydrogen-Ion Concentration; D009682:Magnetic Resonance Spectroscopy; D008968:Molecular Conformation
D000143:Acids; D000255:Adenosine Triphosphate; D001120:Arginine