title: A child with epilepsy: initial presentation and subsequent course.
abstract: Presented is the case of a child with epilepsy with dramatic evolution between the ages of 18 months and 3 years. Initially, the case is one of treatment-responsive focal epilepsy, but then evolves to treatment-resistant focal epilepsy with an epileptic encephalopathy. The case demonstrates the poorly understood entities of age-related changes in seizure suspectibility, seizure types, and drug responsiveness.
authors.affiliation: Division of Neurology, Children's Hospital of Philadelphia, Department of Neurology and Pediatrics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA. dlugos@email.chop.edu
authors.forename: Dennis J
authors.initials: DJ
authors.lastname: Dlugos
mesh_terms: D000367:Age Factors; D017668:Age of Onset; D000927:Anticonvulsants / Q000627:therapeutic use; D002540:Cerebral Cortex / Q000002:abnormalities / Q000503:physiopathology; D002657:Child Development; D002675:Child, Preschool; D004351:Drug Resistance; D004569:Electroencephalography / Q000706:statistics & numerical data; D004827:Epilepsy / Q000175:diagnosis* / Q000188:drug therapy / Q000503:physiopathology; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D008279:Magnetic Resonance Imaging; D008297:Male; D011379:Prognosis; D016896:Treatment Outcome
chemical_list: D000927:Anticonvulsants