title: Fluorescent "light-up" bioprobes based on tetraphenylethylene derivatives with aggregation-induced emission characteristics.
abstract: Aggregation in poor solvents and complexation with calf thymus DNA and bovine serum albumin turn "on" the fluorescence of tetraphenylethylene derivatives, due to the restriction of intra-molecular rotations of the dyes in the aggregates and complexes.
authors.affiliation: Department of Chemistry, Hong Kong University of Science & Technology, Clear Water Bay, Kowloon, Hong Kong, China.
authors.forename: Hui
authors.initials: H
authors.lastname: Tong
authors.forename: Yuning
authors.initials: Y
authors.lastname: Hong
authors.forename: Yongqiang
authors.initials: Y
authors.lastname: Dong
authors.forename: Matthias
authors.initials: M
authors.lastname: Häussler
authors.forename: Jacky W Y
authors.initials: JW
authors.lastname: Lam
authors.forename: Zhen
authors.initials: Z
authors.lastname: Li
authors.forename: Zufeng
authors.initials: Z
authors.lastname: Guo
authors.forename: Zhihong
authors.initials: Z
authors.lastname: Guo
authors.forename: Ben Zhong
authors.initials: BZ
authors.lastname: Tang
mesh_terms: D015374:Biosensing Techniques / Q000379:methods*; D004396:Coloring Agents / Q000737:chemistry*; D004247:DNA / Q000737:chemistry; D005030:Ethylenes / Q000737:chemistry*; D005453:Fluorescence; D015394:Molecular Structure; D012680:Sensitivity and Specificity; D012710:Serum Albumin, Bovine / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D004396:Coloring Agents; D005030:Ethylenes; D012710:Serum Albumin, Bovine; D004247:DNA; C427203:calf thymus DNA