title: [Research progress in Laggera medicinal plants].
abstract: This paper reviewed the worldwide research progresses of the genus Laggera both on phytochemical and pharmacological work in the past few decades. The main secondary metabolites of this genus are proved to be sesquitepenoids, flavonoids and phenolic acids. Phamacological investigations revealed that the certain extracts of some Laggera species possess significant bioactivities on anti-inflammation, anti-tumor and anti-viral infection. This review afforded the comprehensive description of the active components as to provide useful references to elucidate their historical clinical application on upper respiratory infection, influenza, parotitis, and recurrent herpes viral infection.
authors.affiliation: College of Pharmaceutical Science, Zhejiang University, Hangzhou 310031, China.
authors.forename: Chang-Xin
authors.initials: CX
authors.lastname: Zhou
authors.forename: Di-Yao
authors.initials: DY
authors.lastname: Wu
authors.forename: Xiang-Ping
authors.initials: XP
authors.lastname: Li
authors.forename: Yi-Hang
authors.initials: YH
authors.lastname: Wu
authors.forename: Jun
authors.initials: J
authors.lastname: Zhao
authors.forename: Nan
authors.initials: N
authors.lastname: Dong
authors.forename: Rong-Min
authors.initials: RM
authors.lastname: Yu
authors.forename: Wei
authors.initials: W
authors.lastname: Wei
authors.forename: Qun-Xiong
authors.initials: QX
authors.lastname: Zheng
authors.forename: Han-Dong
authors.initials: HD
authors.lastname: Sun
authors.forename: Xiao-Jiang
authors.initials: XJ
authors.lastname: Hao
authors.forename: Yu
authors.initials: Y
authors.lastname: Zhao
mesh_terms: D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000494:pharmacology* / Q000627:therapeutic use; D000972:Antineoplastic Agents, Phytogenic / Q000494:pharmacology / Q000627:therapeutic use; D000998:Antiviral Agents / Q000494:pharmacology / Q000627:therapeutic use; D005419:Flavonoids / Q000737:chemistry / Q000302:isolation & purification* / Q000627:therapeutic use; D006801:Humans; D007251:Influenza, Human / Q000188:drug therapy; D015394:Molecular Structure; D010309:Parotitis / Q000188:drug therapy; D008517:Phytotherapy; D010946:Plants, Medicinal / Q000737:chemistry; D029626:Ranunculaceae / Q000737:chemistry; D012141:Respiratory Tract Infections / Q000188:drug therapy*; D012717:Sesquiterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000627:therapeutic use
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D000972:Antineoplastic Agents, Phytogenic; D000998:Antiviral Agents; D005419:Flavonoids; D012717:Sesquiterpenes