title: A mechanistic rationalization of unusual kinetic behavior in proline-mediated C-O and C-N bond-forming reactions.
abstract: Kinetic evidence supports the role of the reaction product in the catalytic cycle of proline-mediated alpha-aminoxylation and alpha-amination reactions, providing both design principles as well as a model for the evolution of efficiency in catalysis.
authors.affiliation: Department of Chemistry, Imperial College, London, UK SW7 2AZ.
authors.forename: Suju P
authors.initials: SP
authors.lastname: Mathew
authors.forename: Martin
authors.initials: M
authors.lastname: Klussmann
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Iwamura
authors.forename: David H
authors.initials: DH
authors.lastname: Wells
authors.forename: Alan
authors.initials: A
authors.lastname: Armstrong
authors.forename: Donna G
authors.initials: DG
authors.lastname: Blackmond