title: Influence of radial clearance and rotor motion to hemolysis in a journal bearing of a centrifugal blood pump.
abstract: Hemolysis due to narrow clearance of noncontact bearings is a critical problem for rotary blood pumps. We developed a centrifugal blood pump with a magnetic and hydrodynamic hybrid bearing, and found that the hemolysis in the narrow clearance depends not only on the clearance size, but also on the rotor stability. In this study, we quantified the relation between the hemolysis, radial clearance (c), and rotor stability through the measurement of the rotor motion and hemolysis. As a result, it was confirmed that the rotor of the current pump is stabilized within the oscillation of 20 microm in blood, and the hemolysis decreases with increase in the c, which is the opposite in the unstable rotor motion with the previous pump. In order to theoretically discuss this hemolysis tendency, we implemented hemolysis estimation in the c according to hydrodynamics and hemodynamics. This estimation can represent the measured hemolysis tendency, and revealed that the flow rate has large influence on the hemolysis in the c.
authors.affiliation: Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, Tokyo, Japan. gacha.ao@tmd.ac.jp
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Kataoka
authors.forename: Yuichi
authors.initials: Y
authors.lastname: Kimura
authors.forename: Hajime
authors.initials: H
authors.lastname: Fujita
authors.forename: Setsuo
authors.initials: S
authors.lastname: Takatani
mesh_terms: D002498:Centrifugation; D055590:Electromagnetic Phenomena; D004867:Equipment Design; D006353:Heart-Assist Devices / Q000009:adverse effects*; D006461:Hemolysis; D018056:Hemorheology; D006801:Humans; D008433:Mathematics; D008955:Models, Cardiovascular; D012399:Rotation