title: Effects of iron deficiency in infancy on patterns of motor development over time.
abstract: This longitudinal study of the effects of iron deficiency in infancy assessed motor development over time in 185 healthy Costa Rican children who varied in iron status at 12-23 months. Longitudinal analyses (hierarchical linear modeling) used the Bayley Psychomotor Index before and both 1 week and 3 months after iron treatment in infancy and the Bruninks-Oseretsky Test of Motor Proficiency - long form at 5 years and short form at 11-14 years. Children with chronic severe iron deficiency in infancy had lower motor scores at the beginning of the study and a lower but parallel trajectory for motor scores through early adolescence. Thus, there was no evidence of catch-up in motor development, despite iron therapy in infancy that corrected iron deficiency anemia in all cases.
authors.affiliation: Center for Human Growth and Development, University of Michigan, Ann Arbor, MI 48109-0406, United States.
authors.forename: Tal
authors.initials: T
authors.lastname: Shafir
authors.forename: Rosa
authors.initials: R
authors.lastname: Angulo-Barroso
authors.forename: Agustin
authors.initials: A
authors.lastname: Calatroni
authors.forename: Elias
authors.initials: E
authors.lastname: Jimenez
authors.forename: Betsy
authors.initials: B
authors.lastname: Lozoff
mesh_terms: D002648:Child; D002657:Child Development / Q000502:physiology*; D003364:Costa Rica; D006801:Humans; D007223:Infant; D000090463:Iron Deficiencies; D008137:Longitudinal Studies; D008499:Medical Records; D008875:Middle Aged; D009043:Motor Activity / Q000502:physiology*; D011597:Psychomotor Performance / Q000502:physiology*