Intracoronary autologous bone marrow cell transplantation beneficially modulates heart rate variability.
The effect of intracoronary administration of autologous bone marrow cells on autonomic modulation of heart rate has not yet been demonstrated. Therefore, we investigated different parameters of heart rate variability (HRV) in 46 patients without (n=23) or with (n=23) intracoronary stem cell therapy after transmural myocardial infarction. After three to twelve months of follow up, patients receiving stem cells showed a significant increase of HRV parameters that have been linked to cardiovascular prognosis.
Schueller
Per Otto
PO
Meyer
Christian
C
Brehm
Michael
M
Wernet
P
P
Schannwell
Christiana Mira
CM
Strauer
Bodo Eckehard
BE
D000368:Aged; D016026:Bone Marrow Transplantation / Q000379:methods*; D006339:Heart Rate / Q000502:physiology*; D006801:Humans; D008875:Middle Aged; D009203:Myocardial Infarction / Q000503:physiopathology* / Q000628:therapy*; D014182:Transplantation, Autologous