Early detection of viral excretion from experimentally infected goats with peste-des-petits ruminants virus.
We observed 15 goats for 9 days after subcutaneous infection with 10(3) TCID(50) with isolates of peste-des-petits ruminants virus from Africa and India and five concurrent, uninfected control goats. Typical clinical signs of the infection were present in all 15 infected goats by day 8 and in most by day 6 and some signs were present by day 4. However, 6 out of 15 goats already have detectable virus shedding by day 3 and four more were shedding by day 4 and every goat had virus shedding for at least 1 day before the recognition of clinical signs. This experiment indicates that incubatory carriers therefore might play a role in the transmission of PPRV among small ruminants.
Couacy-Hymann
E
E
LANADA/Laboratoire Central de Pathologie Animale de Bingerville, Cote-d'Ivoire. e.couacy-hymann@lanada.ci
Bodjo
S C
SC
Danho
T
T
Koffi
M Y
MY
Libeau
G
G
Diallo
A
A
D017954:Africa South of the Sahara; D000818:Animals; D001831:Body Temperature; D002353:Carrier State / Q000662:veterinary* / Q000821:virology; D015511:Goat Diseases / Q000635:transmission / Q000821:virology*; D006041:Goats; D029021:Peste-des-Petits-Ruminants / Q000635:transmission / Q000662:veterinary* / Q000821:virology; D018107:Peste-des-petits-ruminants virus / Q000235:genetics / Q000254:growth & development*; D012367:RNA, Viral / Q000737:chemistry / Q000235:genetics; D011897:Random Allocation; D020133:Reverse Transcriptase Polymerase Chain Reaction / Q000662:veterinary; D017201:Virus Shedding
D012367:RNA, Viral