title: [Hypertension in polycystic ovary syndrome].
abstract: Polycystic ovary syndrome (PCOS) is associated with multiple cardiovascular risk factors. The aims of this study are to investigate the prevalence of hypertension in a female population with PCOS and to correlate hypertension with her clinical and hormonal profile.
  
  
  METHODS
  it is a transversal study of 79 PCOS patients with mean age of 25 +/- 7 years (range 13-44). PCOS diagnosis is made by Rotterdam consensus criteria's (2003). WHO definition of hypertension is used (BP 140/90 mmHg). Blood pressure is measured three times in each patient. Ovarian echography and biochemical assays (GnRH test, androgens, cholesterol, triglycerides, and oral glucose tolerance test) are made before the 5th day of the menstrual cycle.
  
  
  RESULTS
  12% of PCOS women have hypertension. Family history of hypertension is not a predictive factor of hypertension in our study. PCOS patients with hypertension are not significantly older than those without hypertension (28.4 +/- 6.5 vs. 25.2 +/- 7; p = 0.12). If compared to PCOS women without hypertension, those with hypertension have a significantly higher BMI (39.2 +/- 7 vs. 29.6; p = 0.0004). PCOS patients with and without hypertension do not differ significantly in their level of androgens and total cholesterol. Triglycerides level is higher in PCOS patients with hypertension (p = 0.06). In oral glucose tolerance test, areas under the curve of insulin and glucose are significantly higher in PCOS patients with hypertension (respectively p = 0.06 and 0.02). The area under the curve of LH during GnRH test is lower in PCOS patients with hypertension (p = 0.04).
authors.affiliation: Unité de recherche en endocrinologie de la reproduction, Institut national de nutrition, Bab Sâadoun, Tunis, Tunisie. leila.bensalem@rns.tn
authors.forename: L
authors.initials: L
authors.lastname: Ben Salem Hachmi
authors.forename: S
authors.initials: S
authors.lastname: Ben Salem Hachmi
authors.forename: C
authors.initials: C
authors.lastname: Bouzid
authors.forename: N
authors.initials: N
authors.lastname: Younsi
authors.forename: H
authors.initials: H
authors.lastname: Smida
authors.forename: R
authors.initials: R
authors.lastname: Bouguerra
authors.forename: C
authors.initials: C
authors.lastname: Ben Slama
mesh_terms: D000293:Adolescent; D000328:Adult; D001786:Blood Glucose / Q000032:analysis; D015992:Body Mass Index; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D006937:Hypercholesterolemia / Q000453:epidemiology; D006973:Hypertension / Q000453:epidemiology*; D007328:Insulin / Q000097:blood; D011085:Polycystic Ovary Syndrome / Q000453:epidemiology*; D014280:Triglycerides / Q000097:blood; D014416:Tunisia / Q000453:epidemiology
chemical_list: D001786:Blood Glucose; D007328:Insulin; D014280:Triglycerides