title: Modelling microtubule patterns.
abstract: The cellular cytoskeleton is well studied in terms of its biological and physical properties, making it an attractive subject for systems approaches. Here, we describe the experimental and theoretical strategies used to study the collective behaviour of microtubules and motors. We illustrate how this led to the beginning of an understanding of dynamic cellular patterns that have precise functions.
authors.affiliation: European Molecular Systems Biology Laboratory, Meyerhofstrasse 1, 69117 Heidelberg, Germany. karsenti@embl.de
authors.forename: Eric
authors.initials: E
authors.lastname: Karsenti
authors.forename: François
authors.initials: F
authors.lastname: Nédélec
authors.forename: Thomas
authors.initials: T
authors.lastname: Surrey
mesh_terms: D000255:Adenosine Triphosphate / Q000737:chemistry / Q000378:metabolism; D000465:Algorithms; D000818:Animals; D006801:Humans; D007700:Kinetics; D008870:Microtubules / Q000737:chemistry / Q000378:metabolism*; D008954:Models, Biological; D008956:Models, Chemical; D011485:Protein Binding; D014404:Tubulin / Q000737:chemistry / Q000378:metabolism*
chemical_list: D014404:Tubulin; D000255:Adenosine Triphosphate