title: Vagus nerve stimulation for intractable seizures in children.
abstract: Forty-three children less than 12 years of age having intractable seizures were treated with vagus nerve stimulation. Five children were monitored for <12 months, 16 children for 12 to 17 months, and 22 children for > or =18 months with overall median seizure reduction of 55%. Thirty-seven percent had at least 90% reduction. Vagus nerve stimulation was effective in children with generalized, mixed, and partial medically refractory seizures.
authors.affiliation: Division of Pediatric Neurology, Children's Hospital and Regional Medical Center/University of Washington, Seattle, WA 98105, USA. russ.saneto@seattlechildrens.org
authors.forename: Russell P
authors.initials: RP
authors.lastname: Saneto
authors.forename: Marcio A
authors.initials: MA
authors.lastname: Sotero de Menezes
authors.forename: Jeffrey G
authors.initials: JG
authors.lastname: Ojemann
authors.forename: Brian D
authors.initials: BD
authors.lastname: Bournival
authors.forename: Patricia J
authors.initials: PJ
authors.lastname: Murphy
authors.forename: William B
authors.initials: WB
authors.lastname: Cook
authors.forename: Anthony M
authors.initials: AM
authors.lastname: Avellino
authors.forename: Richard G
authors.initials: RG
authors.lastname: Ellenbogen
mesh_terms: D000367:Age Factors; D002648:Child; D004599:Electric Stimulation Therapy; D004567:Electrodes, Implanted; D004827:Epilepsy / Q000628:therapy*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D012189:Retrospective Studies; D016896:Treatment Outcome; D014630:Vagus Nerve