Failure of Listeria monocytogenes keratitis to respond to topical ofloxacin.
OBJECTIVE
The purpose of this case report is to demonstrate the need for identification of the offending pathogen in bacterial keratitis to guide appropriate treatment.


METHODS
Case report.


RESULTS
We report a case of Listeria monocytogenes keratitis in a young healthy adult that failed to respond to standard empirical therapy for bacterial keratitis but was treated successfully with topical ampicillin, chloramphenicol, and systemic amoxicillin.


CONCLUSIONS
This case demonstrates the need for identification of the offending pathogen to guide appropriate treatment. It also demonstrates discrepancy between in vitro sensitivity and clinical response.
Altaie
Rasha
R
Department of Ophthalmology, University College Hospital Galway, Galway, Republic of Ireland. raltaie2003@yahoo.com
Fahy
Gerard T
GT
Cormican
Martin
M
D000293:Adolescent; D000900:Anti-Bacterial Agents / Q000008:administration & dosage*; D003315:Cornea / Q000382:microbiology / Q000473:pathology; D024881:Drug Resistance, Bacterial; D015818:Eye Infections, Bacterial / Q000188:drug therapy* / Q000382:microbiology / Q000473:pathology; D006801:Humans; D007634:Keratitis / Q000188:drug therapy* / Q000382:microbiology / Q000473:pathology; D008089:Listeria monocytogenes / Q000302:isolation & purification*; D008088:Listeriosis / Q000188:drug therapy* / Q000382:microbiology / Q000473:pathology; D008297:Male; D015242:Ofloxacin / Q000008:administration & dosage*; D009883:Ophthalmic Solutions; D017211:Treatment Failure
D000900:Anti-Bacterial Agents; D009883:Ophthalmic Solutions; D015242:Ofloxacin