A new internal pair production branching ratio of 90Y: the development of a non-destructive assay for 90Y and 90Sr.
(90)Y is utilized as a therapeutic radioisotope in radiolabeled monoclonal antibodies and in microspheres for targeted radiation therapy of the liver. Currently, the widely used dose calibrator assay of (90)Y can have uncertainties exceeding +/-10%. A non-destructive assay using spectroscopy is possible by reducing the currently published uncertainty (+/-12%) in the internal pair production branching ratio for the 0(+)-0(+) transition of (90)Zr. A high-purity germanium detector was used to determine the branching ratio to be (31.86+/-0.47) x 10(-6).
Selwyn
R G
RG
Department of Medical Physics, University of Wisconsin-Madison, Madison, WI 57306, USA. selwyn@wisc.edu <selwyn@wisc.edu>
Nickles
R J
RJ
Thomadsen
B R
BR
DeWerd
L A
LA
Micka
J A
JA
D002138:Calibration; D011834:Radiation Monitoring / Q000379:methods*; D013326:Strontium Radioisotopes / Q000032:analysis*; D015021:Yttrium Radioisotopes / Q000032:analysis*
D013326:Strontium Radioisotopes; D015021:Yttrium Radioisotopes