title: Corneal ectasia and hydrops in a patient with autosomal recessive cornea plana.
abstract: OBJECTIVE
  To report the development of corneal ectasia and hydrops in a patient with autosomal recessive cornea plana.
  
  
  METHODS
  Retrospective observational case report.
  
  
  RESULTS
  A 16-year-old male with a prior diagnosis of autosomal recessive cornea plana who complained of unilateral visual loss of one month's duration was found to have corneal edema consistent with resolving hydrops in the affected eye. The edema resolved over time, and keratometry revealed high astigmatism in both eyes despite documentation of no significant corneal astigmatism 11 years before. Slit-lamp examination confirmed corneal thinning in both eyes corresponding to the meridian of the astigmatism. The prior diagnosis of cornea plana was confirmed by molecular genetic testing.
  
  
  CONCLUSIONS
  Although not a characteristic finding of cornea plana, corneal ectasia can rarely occur and be associated with corneal hydrops.
authors.affiliation: Division of Pediatric Ophthalmology, King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia. arif.khan@mssm.edu
authors.forename: Arif O
authors.initials: AO
authors.lastname: Khan
authors.forename: Mohammed
authors.initials: M
authors.lastname: Aldahmesh
authors.forename: Brian
authors.initials: B
authors.lastname: Meyer
mesh_terms: D000293:Adolescent; D001251:Astigmatism / Q000209:etiology; D003316:Corneal Diseases / Q000235:genetics*; D015715:Corneal Edema / Q000235:genetics*; D019781:Corneal Topography; D004108:Dilatation, Pathologic / Q000235:genetics; D005136:Eye Proteins / Q000235:genetics*; D005808:Genes, Recessive; D006801:Humans; D007640:Keratoconus / Q000235:genetics*; D008297:Male; D009154:Mutation; D011509:Proteoglycans / Q000235:genetics*
chemical_list: D005136:Eye Proteins; C490948:KERA protein, human; D011509:Proteoglycans