title: Hearing loss in rheumatoid arthritis.
abstract: OBJECTIVE
  The objective of this study was to evaluate whether patients with rheumatoid arthritis (RA) are more likely to have subclinical hearing loss compared with persons without RA.
  
  
  METHODS
  This is a case-control cross-sectional study of 29 patients with RA with disease duration greater than 5 years. Five males and five females were recruited into each decade category (age 40-49, 50-59, and 60-69). These cases were matched in a 1:1 ratio by sex and age to 30 control subjects. A comprehensive set of audiometric and disease severity assessments were performed.
  
  
  RESULTS
  Seventeen (59%) of 29 patients with RA had abnormal hearing for at least one frequency (four in one ear, 13 in two ears) by audiometry as did 14 (47%) of 30 control subjects (five in one ear, nine in two ears). The percentage of patients with hearing loss (% RA vs. % control subjects) was: 45% versus 40% sensorineural, 10% versus 7% conductive, and 3% versus 0% mixed hearing loss. In RA versus control subjects, acoustic reflex threshold was abnormal in 17% versus 7%; speech reception threshold was abnormal in 10% versus 3%. Tympanometry and otoacoustic emission findings were similar in both groups. Word recognition did not differ between patients with RA and control subjects. In patients with RA/control subjects, hearing handicap, dizziness, and health assessment questionnaires were abnormal in 28%/7%, 14%/3%, and 72%/7%, respectively.
  
  
  CONCLUSIONS
  There was no difference found in objective audiometric measurements in patients with RA compared with non-RA control subjects. Subjectively patients with RA were more likely to perceive themselves as having hearing disturbances, which may be related to overall disease related functional impairment.
authors.affiliation: Division of Rheumatology, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA.
authors.forename: Christine S
authors.initials: CS
authors.lastname: Halligan
authors.forename: Christopher D
authors.initials: CD
authors.lastname: Bauch
authors.forename: Robert H
authors.initials: RH
authors.lastname: Brey
authors.forename: Sara J
authors.initials: SJ
authors.lastname: Achenbach
authors.forename: William R
authors.initials: WR
authors.lastname: Bamlet
authors.forename: Thomas J
authors.initials: TJ
authors.lastname: McDonald
authors.forename: Eric L
authors.initials: EL
authors.lastname: Matteson
mesh_terms: D000158:Acoustic Impedance Tests; D000328:Adult; D000368:Aged; D001172:Arthritis, Rheumatoid / Q000150:complications*; D001301:Audiometry, Pure-Tone; D001844:Bone Conduction; D003430:Cross-Sectional Studies; D005260:Female; D034381:Hearing Loss / Q000209:etiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D017084:Otoacoustic Emissions, Spontaneous