title: [Uncontrollable bleeding in a patient with head trauma treated with blood component therapy guided by thromboelastography].
abstract: This is a case report concerning a patient with traumatic uncontrolled bleeding. The patient was admitted with a severe head injury and facial fractures. During neurosurgery, the bleeding became life-threatening and there was a request for recombinant factor VIIa therapy (NovoSeven). Before the treatment, thromboelastography was performed. This showed platelet insufficiency, and after infusion of platelets, the bleeding was under control and there was no longer a need for recombinant factor VIIa therapy. We therefore recommend thromboelastography to evaluate coagulation status before treatment with recombinant factor VIIa.
authors.affiliation: Odense Universitetshospital, Anaestesiologisk og Intensiv Afdeling V.
authors.forename: Mads Koch
authors.initials: MK
authors.lastname: Hansen
authors.forename: Marianne Kjaer
authors.initials: MK
authors.lastname: Jensen
authors.forename: Claus
authors.initials: C
authors.lastname: Andersen
mesh_terms: D000328:Adult; D016063:Blood Loss, Surgical; D020201:Brain Hemorrhage, Traumatic / Q000097:blood / Q000175:diagnosis / Q000628:therapy*; D006259:Craniocerebral Trauma / Q000601:surgery; D015942:Factor VIIa / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D017713:Platelet Transfusion; D011994:Recombinant Proteins / Q000627:therapeutic use*; D013916:Thrombelastography
chemical_list: D011994:Recombinant Proteins; D015942:Factor VIIa