title: [Extraction optimization study of flavonoids from Humulus lupulus].
abstract: OBJECTIVE
  To optimize extracting parameters of flavonoids from Humulus lupulus.
  
  
  METHODS
  Based on the single factors test on ethanol concentration, material and solvent ratio, extracting temperature and extracting time, orthogonal test was performed and the best combination was confirmed.
  
  
  RESULTS
  With the optimized technology, the maximal extracting amount of flavonoids from H. lupulus was 78 mg x g(-1).
  
  
  CONCLUSIONS
  The optimal techniques obtained are 45% ethanol extracting at 60 degrees C with material and solvent ratio 1:25 for 90 min.
authors.affiliation: College of Biosystem Engineering and Food Science, Zhejiang University, Hangzhou 310029, China.
authors.forename: Hao-ping
authors.initials: HP
authors.lastname: Xiong
authors.forename: Guo-qing
authors.initials: GQ
authors.lastname: He
authors.forename: Guo-dong
authors.initials: GD
authors.lastname: Xuan
authors.forename: Hui
authors.initials: H
authors.lastname: Ruan
mesh_terms: D000431:Ethanol; D005419:Flavonoids / Q000302:isolation & purification*; D035264:Flowers / Q000737:chemistry; D027582:Humulus / Q000737:chemistry*; D010946:Plants, Medicinal / Q000737:chemistry*; D013678:Technology, Pharmaceutical / Q000379:methods*; D013696:Temperature; D013995:Time
chemical_list: D005419:Flavonoids; D000431:Ethanol