title: [Blood pressure circadian rhythms during development of hypertension in healthy pregnant women].
abstract: Investigation of systolic (SBP) and diastolic blood pressures (DBP) circadian chronological structure changes by means of blood pressure monitoring in healthy pregnant women during development of gestational hypertension (GH) and pre-eclampsia (PE) was carried out. 72 hours blood pressure monitoring (TM-2421 device, Tokyo, Japan) was carried out in 34 healthy pregnant women. Parametric and non-parametric indices of circadian rhythms were determined, which allowed us to include in group A 17 women who had normal BP until delivery. Group B consisted of 17 women with hypertension in II and III trimesters. Increase of hyperbaric index (HBI) of SBP was revealed in the I trimester in women in whom hypertension was developed later in pregnancy. HBI was used as a prognostic criterion of developing MESOR-hypertension long before its clinical manifestation. In the II and III trimesters HBI, per cent time of elevation (PTE%) and MESORs of SBP and DBP circadian rhythms progressively augmented. Pregnant women with hypertension belonged to type non-dipper according to D/N% changes (less then 10%). This may be the result of insufficient decrease of night values of SBP in group B pregnant women, which is characteristic of GH and PE.
authors.forename: M G
authors.initials: MG
authors.lastname: Shaginian
mesh_terms: D002940:Circadian Rhythm / Q000502:physiology*; D005260:Female; D006304:Health Status; D006801:Humans; D006973:Hypertension / Q000453:epidemiology* / Q000503:physiopathology; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000503:physiopathology; D011261:Pregnancy Trimester, First