title: Erosive papulonodular dermatosis associated with topical benzocaine: a report of two cases and evidence that granuloma gluteale, pseudoverrucous papules, and Jacquet's erosive dermatitis are a disease spectrum.
abstract: Granuloma gluteale infantum/adultorum, pseudoverrucous papules, and Jacquet's erosive diaper dermatitis are fairly uncommon manifestations of irritant contact dermatitis historically thought to be distinct clinical entities. Here we report two informative cases of an erosive papulonodular dermatosis in the genital and suprapubic area associated with topical benzocaine. We review granuloma gluteale infantum, pseudoverrucous papules and nodules, and Jacquet's erosive diaper dermatitis, and propose that these disorders may all be variants of genitocrural irritant dermatitis.
authors.affiliation: Department of Dermatology, University of Utah, USA. krobson@med.umich.edu
authors.forename: Kristi J
authors.initials: KJ
authors.lastname: Robson
authors.forename: Julie A
authors.initials: JA
authors.lastname: Maughan
authors.forename: Susan D
authors.initials: SD
authors.lastname: Purcell
authors.forename: Marta J
authors.initials: MJ
authors.lastname: Petersen
authors.forename: Hope K
authors.initials: HK
authors.lastname: Haefner
authors.forename: Lori
authors.initials: L
authors.lastname: Lowe
mesh_terms: D000287:Administration, Topical; D000328:Adult; D000779:Anesthetics, Local / Q000008:administration & dosage / Q000009:adverse effects*; D001566:Benzocaine / Q000008:administration & dosage / Q000009:adverse effects*; D003877:Dermatitis, Contact / Q000473:pathology*; D003963:Diaper Rash; D005260:Female; D006801:Humans; D014845:Vulvar Diseases / Q000139:chemically induced*
chemical_list: D000779:Anesthetics, Local; D001566:Benzocaine