Theoretical estimation of retinal oxygenation during retinal detachment.
The aim of the present work was to simulate the oxygenation of the whole retina during different degrees of retinal detachment. A differential equation describing the oxygenation of the whole retina, at different degrees of detachment, was set up and solved numerically. The results show that the choroid can supply the outer retina with a fairly large amount of oxygen as long as the detachment height is lower than about 1mm. This study thus supports the view that hyperoxia may well prove to be clinically beneficial.
Roos
Magnus W
MW
Department of Medical Sciences, Clinical Physiology, Uppsala University, Akademiska University Hospital, Entr. 35, 751 85 Uppsala, Sweden. Magnus.Roos@medsci.uu.se
D002829:Choroid / Q000378:metabolism; D003198:Computer Simulation; D006801:Humans; D018496:Hyperoxia / Q000378:metabolism; D008954:Models, Biological; D010100:Oxygen / Q000097:blood / Q000378:metabolism*; D010101:Oxygen Consumption; D012160:Retina / Q000378:metabolism*; D012163:Retinal Detachment / Q000097:blood / Q000378:metabolism*; D012171:Retinal Vessels / Q000378:metabolism
D010100:Oxygen