Subcutaneous nodular sarcoidosis and systemic involvement successfully treated with doxycycline.
Subcutaneous nodular sarcoidosis is a rare cutaneous manifestation of systemic sarcoidosis. We report a new case in a 45-year-old woman with a 7-year history of subcutaneous nodules and a new onset of dyspnea. She was treated with corticosteroids but her disease recurred upon withdrawal. A 6-month course of doxycycline in a dose of 200 mg/d led to complete remission. We also emphasize the value of systemic work-up and regular screening in such cases.
El Sayed
Fouad
F
Division of Dermatology, Faculty of Medicine, Lebanese University, Beirut, Lebanon. fsayed@terra.net.lb
Dhaybi
Rola
R
Ammoury
Alfred
A
D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D004318:Doxycycline / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008875:Middle Aged; D012507:Sarcoidosis / Q000188:drug therapy*; D012871:Skin Diseases / Q000188:drug therapy*; D040521:Subcutaneous Tissue
D000900:Anti-Bacterial Agents; D004318:Doxycycline