title: Endovascular management of cerebral vasospasm.
abstract: Cerebral vasospasm remains a leading cause of death and disability in patients with ruptured cerebral aneurysms. The development of endovascular intervention in the past two decades has shown promising results in the treatment of vasospasm. Endovascular techniques that have been used in humans include intra-arterial infusion of vasorelaxants and direct mechanical dilation with transluminal balloon angioplasty. This article reviews the current indications and role of endovascular therapy in the management of cerebral vasospasm, its clinical significance, and potential future therapies.
authors.affiliation: Department of Neurological Surgery, University of California, Davis, Sacramento, CA 95817, USA. mzwien@ucdavis.edu
authors.forename: Marike
authors.initials: M
authors.lastname: Zwienenberg-Lee
authors.forename: Jonathan
authors.initials: J
authors.lastname: Hartman
authors.forename: Nancy
authors.initials: N
authors.lastname: Rudisill
authors.forename: Jan Paul
authors.initials: JP
authors.lastname: Muizelaar
mesh_terms: D001807:Blood Vessel Prosthesis / Q000639:trends*; D002404:Catheterization / Q000639:trends*; D004621:Embolization, Therapeutic / Q000639:trends*; D006801:Humans; D019635:Neurosurgical Procedures / Q000639:trends*; D019651:Plastic Surgery Procedures / Q000639:trends; D015607:Stents; D016896:Treatment Outcome; D014656:Vascular Surgical Procedures / Q000639:trends*; D014665:Vasodilator Agents / Q000008:administration & dosage*; D020301:Vasospasm, Intracranial / Q000628:therapy*
chemical_list: D014665:Vasodilator Agents