title: [Bioactive isomalabaricane triterpenes isolated from marine sponge Rhabdastrella aff. distincta].
abstract: OBJECTIVE
  To study the chemical constituents of the marine sponge Rhabdastrella aff. distincta.
  
  
  METHODS
  Compounds were obtained by normal phase silica gel, Sephadex LH-20, reverse phase chromatogrophy and methylation method. These structures were determined on the basis of IR, MS, NMR spectral analysis.
  
  
  RESULTS
  Eight compounds were isolated from bioactive CH3Cl fraction and identified as geoditin A (1), geoditin B (2), stellettin A (5), stellettin B (4), stellettin C (3), stellettinE (7), rhabdastrellic acid A (8) and the methyl ester of stellettin E (6).
  
  
  CONCLUSIONS
  All these compounds were obtained from this species for the first time.
authors.affiliation: State Key laboratory of Natural and Biomimetic Drugs, Peking University, Beijing 100083, China.
authors.forename: Fang
authors.initials: F
authors.lastname: Lu
authors.forename: Wen-han
authors.initials: WH
authors.lastname: Lin
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000302:isolation & purification / Q000494:pharmacology*; D018922:HL-60 Cells / Q000187:drug effects; D006367:HeLa Cells / Q000187:drug effects; D006801:Humans; D008419:Materia Medica / Q000302:isolation & purification* / Q000494:pharmacology; D011161:Porifera / Q000737:chemistry*; D012118:Resorcinols / Q000302:isolation & purification* / Q000494:pharmacology; D014315:Triterpenes / Q000302:isolation & purification* / Q000494:pharmacology; D014407:Tumor Cells, Cultured / Q000187:drug effects
chemical_list: D000970:Antineoplastic Agents; D008419:Materia Medica; D012118:Resorcinols; D014315:Triterpenes; C445692:geoditin A; C445693:geoditin B; C452212:stellettin B; C091312:stellettin A