Fluorescent "light-up" bioprobes based on tetraphenylethylene derivatives with aggregation-induced emission characteristics.
Aggregation in poor solvents and complexation with calf thymus DNA and bovine serum albumin turn "on" the fluorescence of tetraphenylethylene derivatives, due to the restriction of intra-molecular rotations of the dyes in the aggregates and complexes.
Tong
Hui
H
Department of Chemistry, Hong Kong University of Science & Technology, Clear Water Bay, Kowloon, Hong Kong, China.
Hong
Yuning
Y
Dong
Yongqiang
Y
Häussler
Matthias
M
Lam
Jacky W Y
JW
Li
Zhen
Z
Guo
Zufeng
Z
Guo
Zhihong
Z
Tang
Ben Zhong
BZ
D015374:Biosensing Techniques / Q000379:methods*; D004396:Coloring Agents / Q000737:chemistry*; D004247:DNA / Q000737:chemistry; D005030:Ethylenes / Q000737:chemistry*; D005453:Fluorescence; D015394:Molecular Structure; D012680:Sensitivity and Specificity; D012710:Serum Albumin, Bovine / Q000737:chemistry; D013237:Stereoisomerism
D004396:Coloring Agents; D005030:Ethylenes; D012710:Serum Albumin, Bovine; D004247:DNA; C427203:calf thymus DNA