title: Improvement of episodic memory in persons with mild cognitive impairment and healthy older adults: evidence from a cognitive intervention program.
abstract: The efficacy of cognitive training was assessed in persons with mild cognitive impairment (MCI) and persons with normal cognitive aging. Forty-seven participants were included in this study: 28 with MCI and 17 controls. Twenty-one participants received intervention (20 MCI and 9 controls) and 16 participants (8 MCI and 8 controls) received no intervention (waiting-list group). The intervention focused on teaching episodic memory strategies. Three tasks of episodic memory (list recall, face-name association, text memory) were used as primary outcome measures. Results were analyzed using analyses of variance. The intervention effect (pre- and post-intervention difference) was significant on two of the primary outcome measures (delayed list recall and face-name association). A significant pre-post-effect was also found on measures of subjective memory and well-being. There was no improvement in the performance of groups of individuals with MCI and normal elderly persons who did not receive the intervention. These results suggest that persons with MCI can improve their performance on episodic memory when provided with cognitive training.
authors.affiliation: Institut Universitaire de Gériatrie de Montréal, Montreal, Canada. sylvie.belleville@umontreal.ca
authors.forename: Sylvie
authors.initials: S
authors.lastname: Belleville
authors.forename: Brigitte
authors.initials: B
authors.lastname: Gilbert
authors.forename: Francine
authors.initials: F
authors.lastname: Fontaine
authors.forename: Lise
authors.initials: L
authors.lastname: Gagnon
authors.forename: Edith
authors.initials: E
authors.lastname: Ménard
authors.forename: Serge
authors.initials: S
authors.lastname: Gauthier
mesh_terms: D000368:Aged; D001288:Attention; D003072:Cognition Disorders / Q000175:diagnosis / Q000453:epidemiology*; D003194:Computer-Assisted Instruction; D003710:Demography; D005240:Feasibility Studies; D005260:Female; D005793:Generalization, Psychological; D006304:Health Status; D006801:Humans; D007092:Imagination; D008297:Male; D008569:Memory Disorders / Q000175:diagnosis / Q000453:epidemiology* / Q000628:therapy*; D011939:Mental Recall; D009483:Neuropsychological Tests; D009484:Neuropsychology / Q000379:methods*; D010349:Patient Compliance / Q000706:statistics & numerical data; D016730:Program Development; D012064:Relaxation Therapy; D012660:Semantics; D012720:Severity of Illness Index; D011795:Surveys and Questionnaires; D013663:Teaching / Q000379:methods