title: Wavefront analysis and contrast sensitivity of aspheric and spherical intraocular lenses: a randomized prospective study.
abstract: OBJECTIVE
  To compare visual performance, total and high order wavefront aberrations (coma, spherical aberration, and other terms), and contrast sensitivity in 120 eyes implanted with one monofocal aspheric intraocular lens (IOL) and two spherical IOLs.
  
  
  METHODS
  Randomized prospective study.
  
  
  METHODS
  Sixty patients were randomized to receive three IOL types: Alcon AcrySofIQ (40 eyes), AcrySofNatural (40 eyes), and advanced medical optic (AMO)Sensar (40 eyes). Complete ophthalmologic examination including uncorrected visual acuity (UCVA), best-spectacle corrected visual acuity (BSCVA), corneal topography, and wavefront analysis were performed preoperatively, 30 days, and 90 days postoperatively. Pelli-Robson chart test and functional acuity contrast testing (FACT-Optec6500) were performed approximately 50 days after surgery. Statistical analyses were performed using analysis chi(2), analysis of variance (ANOVA), and multiple comparisons Tukey test.
  
  
  RESULTS
  After 90 days, all eyes had postoperative BSCVA > or =20/32. The AcrySofIQ IOL showed statistically significant less induction of spherical aberration (P < .001) when compared with the AMOSensar and the AcrySofNatural IOLs. The AMOSensar presented significantly less spherical aberration then the AcrySofNatural (P < .05). The AcrySofIQ also had lower values of total and high-order aberration (HOA) (P < .05) when compared with the AMOSensar and the AcrySofNatural. The mean values of trefoil 9, coma, and HOA root mean square (RMS) decreased between one and three months (P < .001, P < .001, P = .023, P < .001, respectively) in all groups. Mean Pelli-Robson contrast sensitivity values in photopic condition were similar between the groups. The AcrySofIQ showed better results in 3cpd spatial frequency in mesopic condition using FACT-Optec 6500 (P = .008), although there were no statistical differences in photopic and mesopic with glare conditions.
authors.affiliation: Ophthalmology Department, Federal University of Sao Paulo, Sao Paulo, Brazil. karolinne@oftalmo.epm.br
authors.forename: Karolinne Maia
authors.initials: KM
authors.lastname: Rocha
authors.forename: Eduardo S
authors.initials: ES
authors.lastname: Soriano
authors.forename: Maria Regina
authors.initials: MR
authors.lastname: Chalita
authors.forename: Ana Carolina
authors.initials: AC
authors.lastname: Yamada
authors.forename: Kátia
authors.initials: K
authors.lastname: Bottós
authors.forename: Juliana
authors.initials: J
authors.lastname: Bottós
authors.forename: Lisangela
authors.initials: L
authors.lastname: Morimoto
authors.forename: Walton
authors.initials: W
authors.lastname: Nosé
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D015350:Contrast Sensitivity / Q000502:physiology*; D019781:Corneal Topography; D005260:Female; D019466:Glare; D006801:Humans; D019654:Lens Implantation, Intraocular; D007910:Lenses, Intraocular; D008297:Male; D008875:Middle Aged; D018918:Phacoemulsification; D011446:Prospective Studies; D019591:Pseudophakia / Q000503:physiopathology*; D011680:Pupil / Q000502:physiology; D014792:Visual Acuity / Q000502:physiology