C-reactive protein and anemia: implications for patients on dialysis.
C-reactive protein (CRP) is an acute-phase reactant protein that increases significantly in the presence of intercurrent (concurrent) events such as infectious and inflammatory processes. Data indicate that CRP levels correlate with anemia parameters, higher levels being associated with an increased comorbidity burden, lower hemoglobin (Hb) levels, and higher Epoetin alfa dose requirements. This article explores the use of CRP monitoring in patients on dialysis, and the relationship to anemia outcomes.
Breiterman-White
Randee
R
Vanderbilt University Medical Center, Nashville, TN, USA.
D000368:Aged; D018798:Anemia, Iron-Deficiency / Q000188:drug therapy / Q000209:etiology / Q000378:metabolism*; D015415:Biomarkers / Q000378:metabolism; D002097:C-Reactive Protein / Q000276:immunology / Q000378:metabolism*; D003428:Cross Infection / Q000175:diagnosis / Q000209:etiology / Q000378:metabolism; D016903:Drug Monitoring / Q000379:methods / Q000451:nursing / Q000592:standards; D000068817:Epoetin Alfa; D004921:Erythropoietin / Q000627:therapeutic use; D005260:Female; D006301:Health Services Needs and Demand; D006397:Hematinics / Q000627:therapeutic use; D006454:Hemoglobins / Q000378:metabolism; D006801:Humans; D007249:Inflammation; D007676:Kidney Failure, Chronic / Q000150:complications*; D009730:Nursing Assessment / Q000379:methods / Q000592:standards; D011994:Recombinant Proteins; D012016:Reference Values; D006435:Renal Dialysis / Q000009:adverse effects / Q000379:methods* / Q000451:nursing; D015203:Reproducibility of Results; D012307:Risk Factors; D012680:Sensitivity and Specificity; D012720:Severity of Illness Index; D016896:Treatment Outcome
D015415:Biomarkers; D006397:Hematinics; D006454:Hemoglobins; D011994:Recombinant Proteins; D004921:Erythropoietin; D000068817:Epoetin Alfa; D002097:C-Reactive Protein