title: Synthesis and antifungal activity of 1H-indole-4,7-diones.
abstract: 1H-Indole-4,7-diones were synthesized and tested for in vitro antifungal activity against fungi. The synthesized 1H-indole-4,7-diones generally showed good antifungal activity against Candida krusei, Cryptococcus neoformans, and Aspergillus niger. The results suggest that 1H-indole-4,7-diones would be potent antifungal agents.
authors.affiliation: College of Pharmacy, Ewha Womans University, Seodaemun-ku, Seoul 120-750, Republic of Korea. ckryu@mm.ewha.ac.kr
authors.forename: Chung-Kyu
authors.initials: CK
authors.lastname: Ryu
authors.forename: Jung Yoon
authors.initials: JY
authors.lastname: Lee
authors.forename: Rae-Eun
authors.initials: RE
authors.lastname: Park
authors.forename: Mi-Young
authors.initials: MY
authors.lastname: Ma
authors.forename: Ji-Hee
authors.initials: JH
authors.lastname: Nho
mesh_terms: D000935:Antifungal Agents / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology*; D007211:Indoles / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology*; D003904:Mitosporic Fungi / Q000187:drug effects*
chemical_list: D000935:Antifungal Agents; D007211:Indoles