[Fingerprint analysis of composite Folii Isatidis injection by HPLC].
OBJECTIVE
To develop the chromatographic fingerprints of composite Folii Isatidis injection by HPLC.


METHODS
The separation was performed on a Diamonsil C18 column with a mobile phase consisting of methanol-water-phosphoric acid as gradient eluent at the flow rate of 1.0 mL x min(-1). The UV detection was set at 254 nm.


RESULTS
A standard HPLC fingerprint procedure was developed for composite Folii Isatidis injection, with 20 common peaks and a similarity threshold of 9.0 established.


CONCLUSIONS
This method was accurate, repeatable and useful for the quality control of composite Folii Isatidis injection.
Liu
Rui
R
School of Pharmacy, Shenyang Pharmaceutical University, China.
Liu
Zhi-gang
ZG
Li
Lei
L
Ren
Chong
C
Yuan
Bo
B
Li
Fa-mei
FM
D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage / Q000737:chemistry* / Q000302:isolation & purification; D020441:Ginkgo biloba / Q000737:chemistry; D007267:Injections; D031219:Isatis / Q000737:chemistry*; D018515:Plant Leaves / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D011786:Quality Control; D015203:Reproducibility of Results; D014529:Uridine / Q000032:analysis
D004338:Drug Combinations; D004365:Drugs, Chinese Herbal; D014529:Uridine