title: [Interrelationship between lower limb varicosity, the grade of connective tissue dysplasia and atrial fibrillation in patients with coronary artery disease].
abstract: OBJECTIVE
  To determine interrelationship between lower limb varicosity, the clinical grade of non-differentiated dysplasia of the connective tissue and atrial fibrillation in patients with coronary artery disease (CAD).
  
  
  METHODS
  Altogether 156 coronary patients were examined. Persistent atrial fibrillation was present in 58 and chronic in 38 patients. The reference group comprised 60 patients without evident rhythm disorders in persons suffering from CAD. Markers of connective tissue dysplasia (<<stigmas>>) were revealed on the part of the skeleton, joints skin and visceral organs. Lower limb varicosity was recorded as well.
  
  
  RESULTS
  The number of the stigmas in the study groups was different. So, in the patient group without rhythm disorders, the mean number of the stigmas was equal to 3, which is a variant of normal. In the groups with persistent and constant AF, this indicator was equal to 4.7 and 5.2 respectively (p<0.05). The number of patients with evident signs of CID (the number of stigmas 5) was greater in the groups with AP than among patients with normal rhythm. Varicosity was recorded in 41% of both group patients. It is to be noted that in the group with normal rhythm, lower limb varicosity was encountered in 22.1% of cases whereas in the group with AF, in 58.4% of cases with persistent AF and in 41% of cases with constant AF. The mean number of stigmas in the group without varicosity accounted for 3.6 and in patients with varicosity - for 5 (P<0.05).
  
  
  CONCLUSIONS
  When coronary artery disease is coupled with atrial fibrilation there is a direct close correlation between the signs of connective tissue dysplasia and lower limb varicosity. In patients with persistent AF lower limb varicosity occurs more frequently than in CAD patients with normal rhythm.
authors.forename: O V
authors.initials: OV
authors.lastname: Forster
authors.forename: O A
authors.initials: OA
authors.lastname: Tsarev
authors.forename: Iu G
authors.initials: IuG
authors.lastname: Shvarts
mesh_terms: D000368:Aged; D001281:Atrial Fibrillation / Q000150:complications* / Q000453:epidemiology / Q000503:physiopathology; D003240:Connective Tissue Diseases / Q000150:complications* / Q000175:diagnosis / Q000453:epidemiology; D003327:Coronary Disease / Q000150:complications* / Q000453:epidemiology / Q000503:physiopathology; D015716:Electrocardiography, Ambulatory; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012720:Severity of Illness Index; D014648:Varicose Veins / Q000150:complications* / Q000175:diagnosis / Q000453:epidemiology