Hypercalciuria as a cause of genital bleeding in a 6-year-old girl.
OBJECTIVE
To document an unusual cause of genital bleeding in a 6-year-old girl.


METHODS
Case report.


METHODS
Outpatient pediatric gynecology clinic in a tertiary care hospital.


RESULTS
Clinical presentation of a case of genital bleeding secondary to hypercalciuria in a 6-year-old female. Gynecologic investigations were negative. There were hematuria on urinalysis and an elevated calcium-to-creatinine ratio on initial presentation; however, no evidence of urolithiasis was found on ultrasound. In the context of negative investigations and persistent episodes of bleeding, the hypercalciuria was treated with hydrochlorothiazide. Normalization of calciuria was associated with the end of genital bleeding episodes.


CONCLUSIONS
Hypercalciuria with microcrystals and urethral irritation should be considered as part of the differential diagnosis for genital bleeding in girls.
Valcourt
Edith E
EE
Department of Obstetrics and Gynecology, University of Ottawa, Ontario, Canada.
Fleming
Nathalie A
NA
Weiler
Gabrielle
G
D002648:Child; D004232:Diuretics / Q000627:therapeutic use; D005260:Female; D006417:Hematuria / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D006801:Humans; D006852:Hydrochlorothiazide / Q000627:therapeutic use; D053565:Hypercalciuria / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D016896:Treatment Outcome; D014592:Uterine Hemorrhage / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*
D004232:Diuretics; D006852:Hydrochlorothiazide