title: [Optimal modes of epidural analgesia at labor in females at a high risk of complications].
abstract: A total of 1570 females were examined. They were divided into 3 groups: (1) 780 pregnant females and puerperas with varying preeclampsia; (2) 560 pregnant females and puerperas with acquired rheumatic heart diseases; 3) 230 puerperas with chronic nonspecific lung diseases. For labor pain relief Group 1 received continuous epidural analgesia with 1% lidocaine (1 mg/kg) in combination with clonidine (clofelin) (1 microg/kg); Group 2 was given 1% lidocaine (1 mg/kg) in combination with morphine (0.08-0.1 mg/kg); Group 3 had 1% ultracaine (1 mg/kg. The proposed modes of epidural analgesia provide a reliable antinociceptive protection of females at labor and hemodynamic stability and exert no significant negative effect on babies in the early adaptation period.
authors.forename: En Din
authors.initials: ED
authors.lastname: Kim
authors.forename: A A
authors.initials: AA
authors.lastname: Seminikhin
mesh_terms: D015360:Analgesia, Epidural / Q000009:adverse effects / Q000379:methods*; D016362:Analgesia, Obstetrical / Q000009:adverse effects / Q000379:methods*; D000779:Anesthetics, Local / Q000008:administration & dosage; D002355:Carticaine / Q000008:administration & dosage; D003000:Clonidine / Q000008:administration & dosage; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007743:Labor, Obstetric; D008012:Lidocaine / Q000008:administration & dosage; D050498:Live Birth; D011247:Pregnancy; D011248:Pregnancy Complications / Q000175:diagnosis*; D011256:Pregnancy Outcome; D012306:Risk
chemical_list: D000779:Anesthetics, Local; D008012:Lidocaine; D002355:Carticaine; D003000:Clonidine