title: Failure of Listeria monocytogenes keratitis to respond to topical ofloxacin.
abstract: OBJECTIVE
  The purpose of this case report is to demonstrate the need for identification of the offending pathogen in bacterial keratitis to guide appropriate treatment.
  
  
  METHODS
  Case report.
  
  
  RESULTS
  We report a case of Listeria monocytogenes keratitis in a young healthy adult that failed to respond to standard empirical therapy for bacterial keratitis but was treated successfully with topical ampicillin, chloramphenicol, and systemic amoxicillin.
  
  
  CONCLUSIONS
  This case demonstrates the need for identification of the offending pathogen to guide appropriate treatment. It also demonstrates discrepancy between in vitro sensitivity and clinical response.
authors.affiliation: Department of Ophthalmology, University College Hospital Galway, Galway, Republic of Ireland. raltaie2003@yahoo.com
authors.forename: Rasha
authors.initials: R
authors.lastname: Altaie
authors.forename: Gerard T
authors.initials: GT
authors.lastname: Fahy
authors.forename: Martin
authors.initials: M
authors.lastname: Cormican
mesh_terms: D000293:Adolescent; D000900:Anti-Bacterial Agents / Q000008:administration & dosage*; D003315:Cornea / Q000382:microbiology / Q000473:pathology; D024881:Drug Resistance, Bacterial; D015818:Eye Infections, Bacterial / Q000188:drug therapy* / Q000382:microbiology / Q000473:pathology; D006801:Humans; D007634:Keratitis / Q000188:drug therapy* / Q000382:microbiology / Q000473:pathology; D008089:Listeria monocytogenes / Q000302:isolation & purification*; D008088:Listeriosis / Q000188:drug therapy* / Q000382:microbiology / Q000473:pathology; D008297:Male; D015242:Ofloxacin / Q000008:administration & dosage*; D009883:Ophthalmic Solutions; D017211:Treatment Failure
chemical_list: D000900:Anti-Bacterial Agents; D009883:Ophthalmic Solutions; D015242:Ofloxacin