[Administration of Gadobutrol in coronary artery stenting in a female patient with allergy to iodine-containing radiopaque agents].
Presented herein is a case report of a successful treatment of subtotal stenosis of the anterior interventricular artery (over 95%) using paramagnetic contrast agent Gadovist 1.0 in a female patient with a polyvalent allergy, including that to iodine-containing radiopaque substances. Immunological tests for drug intolerance according to the Demyanenko technique using Gadovist 1.0 were followed by coronography and stenting of the anterior interventricular artery. The immediate outcomes were assessed as good: the lumen of the anterior interventricular artery was restored completely, with sufficient filling in of the distal portions of the artery. The total volume of the administered contrast substance amounted to 1.8 ml/kg. No alterations in the markers of the renal function were noted. This case report demonstrates a possibility of using contrast medium Gadovist 1.0 as a radiopaque substance in an endovascular intervention, also confirming that Gadobutrol exerts no side effect on the kidneys, even if administered in high doses.
Kokov
L S
LS
Terekhin
S A
SA
Likharev
A Iu
AIu
Nesuk
O M
OM
Ivanov
L O
LO
D019917:Blood Vessel Prosthesis Implantation / Q000295:instrumentation*; D017023:Coronary Angiography / Q000379:methods*; D023921:Coronary Stenosis / Q000150:complications / Q000000981:diagnostic imaging / Q000601:surgery*; D004342:Drug Hypersensitivity / Q000150:complications*; D005260:Female; D005682:Gadolinium; D006801:Humans; D017613:Iodine Compounds / Q000009:adverse effects*; D008875:Middle Aged; D009942:Organometallic Compounds / Q000008:administration & dosage; D011868:Radioisotopes; D015607:Stents
D017613:Iodine Compounds; D009942:Organometallic Compounds; D011868:Radioisotopes; C090600:gadobutrol; D005682:Gadolinium