Subacute sclerosing panencephalitis with generalized seizure as a first symptom: a case report.
Subacute sclerosing panencephalitis (SSPE) can show variations in its clinical course. Typical initial symptoms consist of intellectual decline, deterioration in school performance, and myoclonic jerks. Atypical forms of presentation such as generalized seizures and acute or subacute coma can be observed rarely. This report describes a 5-year-old boy with an atypical feature of SSPE, generalized seizures. For 1 month his only symptom was seizures, followed by personality and behavioral changes and myoclonic jerks. A diagnosis of SSPE was made based on the boy's history of measles, characteristic electroencephalogram changes and compatible magnetic resonance, and elevated anti-measles antibody titers in the cerebrospinal fluid and serum. The case presented in this article is a good example of SSPE in which, at early stages, some of the signs and symptoms can lead to an erroneous diagnosis.
Tuncel
Deniz
D
Department of Neurology, Kahramanmaras Sutcu Imam University, Kahramanmaras, Turkey. tuncedeniz@yahoo.com
Ozbek
Ayda Ertugrul
AE
Demirpolat
Gülen
G
Karabiber
Hamza
H
D002648:Child; D003937:Diagnosis, Differential; D004569:Electroencephalography / Q000379:methods; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D008457:Measles / Q000150:complications; D008459:Measles virus / Q000302:isolation & purification; D012640:Seizures / Q000175:diagnosis* / Q000821:virology; D013344:Subacute Sclerosing Panencephalitis / Q000175:diagnosis* / Q000473:pathology / Q000821:virology