Recovering metabolic pathways via optimization.
A metabolic pathway is a coherent set of enzyme catalysed biochemical reactions by which a living organism transforms an initial (source) compound into a final (target) compound. Some of the different metabolic pathways adopted within organisms have been experimentally determined. In this paper, we show that a number of experimentally determined metabolic pathways can be recovered by a mathematical optimization model.
Beasley
John E
JE
Mathematical Sciences, Brunel University Uxbridge, UB8 3PH, UK. john.beasley@brunel.ac.uk
Planes
Francisco J
FJ
D053858:Metabolic Networks and Pathways / Q000502:physiology*; D008954:Models, Biological