[Prognostic criteria of systolic-diastolic correlation of medial cerebral artery of fetus in pregnant women with cytomegalovirus infection].
Total of 137 women were studied with pregnancy terms between 20 and 41 weeks; out of them 97 with latent form and reactivation of cytomegalovirus infection, and 40 with non-complicated gestational process. Complex Doppler metrics study of the blood flow in the medial cerebral artery of the fetus using cluster analysis has been carried out. High percentage of complication in the II class of pregnant women has been revealed, where systolic-diastolic correlation index in medial cerebral artery of fetus was in the range of <3.1 and >7.1, compared to I class, where systolic-diastolic correlation index was in the interval of 3.1-7.1. Hypoxic affection of central nervous system in newborn of II class made 59.0+/-6.7% (p<0.001), cerebral blood flow disturbance in 66.7+/-7.0% (p<0.001), post-hypoxic encephalopathy--46.2+/-6.2% (p<0.001). Neuro-reflex stimulation syndrome in the newborn of II class was revealed in 38.5+/-5.7% (p<0.001), hypertensive syndrome--25.6+/-4.8% (p<0.001). Hence, our research showed prognostic value of researching fetus' cerebral hemodynamics in pregnant with cytomegalovirus infection in the III trimester of gestation for revealing perinatal pathology high risk groups.
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D000328:Adult; D001921:Brain / Q000098:blood supply / Q000196:embryology; D002560:Cerebrovascular Circulation / Q000502:physiology; D003586:Cytomegalovirus Infections / Q000453:epidemiology* / Q000382:microbiology*; D005260:Female; D005315:Fetal Diseases / Q000000981:diagnostic imaging / Q000453:epidemiology*; D006801:Humans; D006973:Hypertension / Q000196:embryology / Q000453:epidemiology / Q000503:physiopathology; D020768:Middle Cerebral Artery / Q000196:embryology* / Q000503:physiopathology*; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000382:microbiology*; D011263:Pregnancy Trimester, Third; D011379:Prognosis; D014463:Ultrasonography