title: Proteasomal regulation of cardiac hypertrophy: is demolition necessary for building?
authors.forename: Jeffrey G
authors.initials: JG
authors.lastname: Dickhout
authors.forename: Richard C
authors.initials: RC
authors.lastname: Austin
mesh_terms: D000222:Adaptation, Physiological; D000818:Animals; D001013:Aorta, Thoracic; D017209:Apoptosis / Q000187:drug effects; D001794:Blood Pressure; D003187:Compliance; D004195:Disease Models, Animal; D004285:Dogs; D004721:Endoplasmic Reticulum / Q000378:metabolism; D015852:Eukaryotic Initiation Factor-2 / Q000378:metabolism; D006801:Humans; D017379:Hypertrophy, Left Ventricular / Q000378:metabolism*; D008026:Ligation; D051379:Mice; D009124:Muscle Proteins / Q000378:metabolism; D032383:Myocytes, Cardiac / Q000187:drug effects / Q000201:enzymology / Q000473:pathology; D009842:Oligopeptides / Q000494:pharmacology; D011480:Protease Inhibitors / Q000494:pharmacology; D046988:Proteasome Endopeptidase Complex / Q000502:physiology*; D061988:Proteasome Inhibitors; D017510:Protein Folding; D013312:Stress, Physiological / Q000378:metabolism; D025801:Ubiquitin / Q000378:metabolism; D014655:Vascular Resistance; D020257:Ventricular Remodeling / Q000502:physiology*
chemical_list: D015852:Eukaryotic Initiation Factor-2; D009124:Muscle Proteins; D009842:Oligopeptides; D011480:Protease Inhibitors; D061988:Proteasome Inhibitors; D025801:Ubiquitin; D046988:Proteasome Endopeptidase Complex; C078846:epoxomicin