Potentiality of mesenchymal stem cells in regeneration of sweat glands.
Sweat glands play some key roles in homeostasis maintenance and body temperature regulation. In full-thickness burn wounds, sweat glands cannot regenerate to form their three-dimensional organization via the division and terminal differentiation of sweat gland cells. However, the plasticity of mesenchymal stem cells (MSCs) may offer the hope and potentiality to regenerate sweat glands after severe burn injury.
Fu
Xiaobing
X
Wound Healing and Cell Biology Laboratory, Burns Institute, 304th Clinical Department, The General Hospital of PLA, Trauma Center of Postgraduate Medical College, Beijing, P. R. China. fuxb@cgw.net.cn
Qu
Zhenliang
Z
Sheng
Zhiyong
Z
D000818:Animals; D002056:Burns / Q000473:pathology / Q000628:therapy*; D006801:Humans; D045164:Mesenchymal Stem Cell Transplantation; D059630:Mesenchymal Stem Cells / Q000166:cytology* / Q000502:physiology; D012038:Regeneration; D013545:Sweat Glands / Q000166:cytology / Q000502:physiology*