Self-complementary purines by quadruple hydrogen bonding.
The first discrete, self-complementary, quadruply hydrogen-bonded complexes based on the 2,6-diaminopurine (DAP) scaffold have been prepared; regioselective urea formation at the C2 amino group of the heterocycle allows intermolecular dimerization (K(dim) approximately 1-1.6 x 10(3) M(-1) in CDCl3) through a DADA hydrogen bonding motif.
Martin
Alisha M
AM
Department of Chemistry, University of Florida, PO Box 117200, Gainesville, FL 32611, USA.
Butler
Roslyn S
RS
Ghiviriga
Ion
I
Giessert
Rachel E
RE
Abboud
Khalil A
KA
Castellano
Ronald K
RK