title: [Late secondary syphilis with ulceration of the tongue during HIV coinfection: case report].
abstract: With the continuing rise of syphilis incidence, late stages and atypical courses with HIV-coinfection can be expected. A 45 year old HIV infected male presented with an unusual manifestation of late secondary syphilis on the tongue, which was first diagnosed as a squamous cell carcinoma but cleared after therapy with penicillin. He also exhibited psoriasiform and annular lesions on the trunk and hyperkeratotic papules on the palms of the hand and soles of the feet. A TPHA test was negative due to a prozone phenomenon. With this case, we would like to emphasize the formerly well known relationship between the lesions of tertiary syphilis on the tongue and development of secondary carcinoma.
authors.affiliation: Klinik und Poliklinik für Dermatologie, Universitätsklinikum Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany. Petra.Spornraft-Ragaller@mailbox.tu-dresden.de
authors.forename: P
authors.initials: P
authors.lastname: Spornraft-Ragaller
authors.forename: U
authors.initials: U
authors.lastname: Boashie
authors.forename: K
authors.initials: K
authors.lastname: Friedrich
authors.forename: U
authors.initials: U
authors.lastname: Lehmann
authors.forename: M
authors.initials: M
authors.lastname: Meurer
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D044966:Anti-Retroviral Agents / Q000008:administration & dosage / Q000627:therapeutic use; D001706:Biopsy; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis; D003937:Diagnosis, Differential; D005188:False Negative Reactions; D005533:Foot Dermatoses / Q000175:diagnosis / Q000209:etiology; D015658:HIV Infections / Q000150:complications* / Q000188:drug therapy; D006229:Hand Dermatoses / Q000175:diagnosis / Q000209:etiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D010400:Penicillin G / Q000627:therapeutic use; D013587:Syphilis / Q000150:complications*; D013588:Syphilis Serodiagnosis; D013591:Syphilis, Cutaneous / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D014059:Tongue / Q000473:pathology; D014060:Tongue Diseases / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology; D014062:Tongue Neoplasms / Q000175:diagnosis; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents; D044966:Anti-Retroviral Agents; D010400:Penicillin G