title: Effect of endocervical-specimen adequacy on detection of Chlamydia trachomatis by the APTIMA COMBO 2 assay.
abstract: Six hundred one endocervical specimens were analyzed for Chlamydia trachomatis by the APTIMA Combo 2 assay and evaluated for columnar epithelial cell adequacy by direct fluorescent-antibody staining. With 5.5% positive adequate and 7.8% positive inadequate specimens (P=0.27), the study suggested no difference in positivity rates due to specimen adequacy when this amplified technology was used.
authors.affiliation: Wyoming Public Health Laboratory, 517 Hathaway Bldg., 2300 Capitol Ave., Cheyenne, WY 82002, USA. croger@state.wy.us
authors.forename: C K
authors.initials: CK
authors.lastname: Rogers
authors.forename: B J
authors.initials: BJ
authors.lastname: Wood
authors.forename: P
authors.initials: P
authors.lastname: Rizzo
authors.forename: C A
authors.initials: CA
authors.lastname: Gaydos
mesh_terms: D002584:Cervix Uteri / Q000166:cytology* / Q000382:microbiology*; D002690:Chlamydia Infections / Q000175:diagnosis* / Q000382:microbiology; D002692:Chlamydia trachomatis / Q000302:isolation & purification*; D004847:Epithelial Cells / Q000166:cytology / Q000382:microbiology; D005260:Female; D005455:Fluorescent Antibody Technique; D006801:Humans; D011933:Reagent Kits, Diagnostic; D012680:Sensitivity and Specificity; D013048:Specimen Handling; D013194:Staining and Labeling
chemical_list: D011933:Reagent Kits, Diagnostic