Mixed clear cell and endometrioid carcinoma arising in parietal endometriosis.
OBJECTIVE
We report a case of a mixed clear cell and endometrioid carcinoma arising in parietal endometriosis.


METHODS
A 46-year-old woman presented a second recurrence of parietal endometriosis. An extensive surgical resection of the tumor was then carried out.


RESULTS
Histological analysis revealed heterogeneous tissues including clear cell and endometrioid carcinoma fields arising from a large benign endometriosis lesion. Despite chemotherapy, the patient died 6 months after the diagnosis.


CONCLUSIONS
Clear cell carcinoma and endometrioid carcinoma have been rarely found in parietal endometriosis. Clinicians should learn to suspect a cancerous transformation of a parietal endometriosis, when rapid recurrence and extensive development are observed.
Razzouk
Kais
K
Department of Gynecology and Obstetrics, University Hospital, Rouen, France.
Roman
Horace
H
Chanavaz-Lacheray
Isabella
I
Scotté
Michel
M
Verspyck
Eric
E
Marpeau
Loïc
L
D018262:Adenocarcinoma, Clear Cell / Q000473:pathology / Q000601:surgery*; D018269:Carcinoma, Endometrioid / Q000473:pathology / Q000601:surgery*; D002585:Cesarean Section / Q000009:adverse effects*; D002921:Cicatrix / Q000150:complications; D004715:Endometriosis / Q000473:pathology / Q000601:surgery*; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D008875:Middle Aged