title: [Study on application of activated carbon in paclitaxel injection].
abstract: OBJECTIVE
  To inspect the effect of activated carbon with different dosage and temperature on quality of paclitaxel injection.
  
  
  METHODS
  Determinations in WS1-(X-026)-2001Z-paclitaxel injection were refered to compare the effect of different dosage and temperature for activated carbon on the taxol content, related material, clarity and bacterial endotoxin.
  
  
  RESULTS
  When used with 0.25% and 35 degrees C, activated carbon will ensure the quality of paclitaxel injection.
  
  
  CONCLUSIONS
  0.25% and 35 degrees C are the best condition when activated carbon is used in paclitaxel injection.
authors.affiliation: Southern Medical University, College of Traditional Chinese Medicine, Key Laboratory of Reasearch of Traditional Chinese Medicine and New Drug, Guangzhou, China.
authors.forename: Li
authors.initials: L
authors.lastname: Liu
authors.forename: Jia-bo
authors.initials: JB
authors.lastname: Luo
authors.forename: Xue-feng
authors.initials: XF
authors.lastname: Xing
mesh_terms: D000972:Antineoplastic Agents, Phytogenic / Q000008:administration & dosage*; D002606:Charcoal / Q000008:administration & dosage* / Q000032:analysis; D004339:Drug Compounding / Q000379:methods; D007267:Injections; D017239:Paclitaxel / Q000008:administration & dosage*; D011786:Quality Control; D013696:Temperature
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D002606:Charcoal; D017239:Paclitaxel