title: Intervertebral disc biomechanical analysis using the finite element modeling based on medical images.
abstract: In this paper, a 3D geometric model of the intervertebral and lumbar disks has been presented, which integrated the spine CT and MRI data-based anatomical structure. Based on the geometric model, a 3D finite element model of an L1-L2 segment was created. Loads, which simulate the pressure from above were applied to the FEM, while a boundary condition describing the relative L1-L2 displacement is imposed on the FEM to account for 3D physiological states. The simulation calculation illustrates the stress and strain distribution and deformation of the spine. The method has two characteristics compared to previous studies: first, the finite element model of the lumbar are based on the data directly derived from medical images such as CTs and MRIs. Second, the result of analysis will be more accurate than using the data of geometric parameters. The FEM provides a promising tool in clinical diagnosis and for optimizing individual therapy in the intervertebral disc herniation.
authors.affiliation: College of Biomedical Engineering, Capital University of Medical Sciences, Beijng 100054, China. haiyunli@cpums.edu.cn
authors.forename: Haiyun
authors.initials: H
authors.lastname: Li
authors.forename: Zheng
authors.initials: Z
authors.lastname: Wang
mesh_terms: D001696:Biomechanical Phenomena / Q000379:methods*; D019245:Compressive Strength; D003198:Computer Simulation; D003952:Diagnostic Imaging / Q000379:methods*; D004548:Elasticity; D020342:Finite Element Analysis; D006801:Humans; D007403:Intervertebral Disc / Q000473:pathology / Q000503:physiopathology*; D007405:Intervertebral Disc Displacement / Q000503:physiopathology*; D008159:Lumbar Vertebrae / Q000503:physiopathology*; D008954:Models, Biological; D013314:Stress, Mechanical