[Blood lipids and glucose levels in patients with periodontitis].
OBJECTIVE
To determine the serum levels of lipid and glucose in patients with periodontitis.


METHODS
The patients with aggressive periodontitis (AgP, n = 117) and chronic periodontitis (CP, n = 40) and healthy controls (n = 37) were recruited. Peripheral blood sample was obtained from each subject by venipuncture. Serum chemistry variables including total cholesterol, triglycerides, and fasting glucose were analyzed by biochemical analyzer.


RESULTS
The average serum levels of triglycerides and glucose of the patients with AgP [(1.09 +/- 0.79) mmol/L and (5.07 +/- 0.66) mmol/L] were both significantly higher than those of the control group [(0.94 +/- 0.28) mmol/L and (4.62 +/- 0.64) mmol/L], P < 0.05. Higher serum levels of total cholesterol and glucose were also observed in patients with CP [(4.61 +/- 1.23) mmol/L and (5.40 +/- 1.01) mmol/L] compared with controls [(4.49 +/- 0.78) mmol/L and (4.62 +/- 0.64) mmol/L], P < 0.05. Serum level of total cholesterol in AgP group was positively associated with percentage of severe sites (r = 0.25, P < 0.01).


CONCLUSIONS
Patients with periodontitis may have altered serum lipid and glucose levels compared with controls.
Shi
Dong
D
Department of Periodontology, Peking University School and Hospital of Stomatology, Beijing 100081, China.
Meng
Huan-xin
HX
Xu
Li
L
Zhang
Li
L
Chen
Zhi-bin
ZB
Feng
Xiang-hui
XH
D000293:Adolescent; D000328:Adult; D001786:Blood Glucose / Q000378:metabolism*; D002784:Cholesterol / Q000097:blood*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010518:Periodontitis / Q000097:blood*; D014280:Triglycerides / Q000097:blood*; D055815:Young Adult
D001786:Blood Glucose; D014280:Triglycerides; D002784:Cholesterol