title: Mechanistic insight into copper-catalysed allylic substitutions with bis(triorganosilyl) zincs. Enantiospecific preparation of alpha-chiral silanes.
abstract: Isotopic desymmetrisation, as well as (stereo)chemical correlation, has illuminated significant aspects of the sigma-pi-sigma mechanism of copper-catalysed allylic substitution reactions: an enantiospecific and regioselective access to alpha-chiral silanes is presented.
authors.affiliation: Organisch-Chemisches Institut, Westfälische Wilhelms-Universität, Corrensstrasse 40, D-48149 Münster, Germany.
authors.forename: Eric S
authors.initials: ES
authors.lastname: Schmidtmann
authors.forename: Martin
authors.initials: M
authors.lastname: Oestreich
mesh_terms: D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D012821:Silanes / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism; D015032:Zinc / Q000737:chemistry*
chemical_list: D009942:Organometallic Compounds; D012821:Silanes; D003300:Copper; D015032:Zinc