title: Clinical significance of Staphylococcus saprophyticus identified on blood culture in a tertiary care hospital.
abstract: Staphylococcus saprophyticus is a well-known cause of acute uncomplicated urinary tract infection in young women. However, the clinical significance of this organism isolated from blood culture has not been determined. We assessed the clinical significance and characteristics of S. saprophyticus identified on blood culture. A total of 24 patients were identified, and 7 patients (29.2%) were considered to have clinically significant bacteremia. Of the 7 patients with clinically significant bacteremia, hematologic malignancy was the most common underlying illness (5 patients), and tunneled-central venous catheter was the most common portal of entry (4 patients). In no case did S. saprophyticus bacteremia originate from the urinary tract. One patient died during hospitalization. However, the death was not directly related to bacteremia. In conclusion, our data suggest that bacteremia caused by S. saprophyticus is most commonly associated with tunneled-central venous catheter in patients with hematologic malignancies and may be associated with a lower risk of mortality.
authors.affiliation: Division of Infectious Diseases, Asan Medical Center, University of Ulsan College of Medicine, and Center for Antimicrobial Resistance and Microbial Genetics, University of Ulsan, Seoul 138-736, South Korea.
authors.forename: Sang-Ho
authors.initials: SH
authors.lastname: Choi
authors.forename: Jun Hee
authors.initials: JH
authors.lastname: Woo
authors.forename: Jin-Yong
authors.initials: JY
authors.lastname: Jeong
authors.forename: Nam Joong
authors.initials: NJ
authors.lastname: Kim
authors.forename: Mi-Na
authors.initials: MN
authors.lastname: Kim
authors.forename: Yang Soo
authors.initials: YS
authors.lastname: Kim
authors.forename: Jiso
authors.initials: J
authors.lastname: Ryu
mesh_terms: D000328:Adult; D016470:Bacteremia / Q000453:epidemiology / Q000209:etiology*; D002405:Catheterization, Central Venous / Q000009:adverse effects; D003428:Cross Infection / Q000097:blood / Q000453:epidemiology / Q000209:etiology; D005260:Female; D019337:Hematologic Neoplasms / Q000150:complications; D006760:Hospitalization; D006801:Humans; D008297:Male; D008875:Middle Aged; D013203:Staphylococcal Infections / Q000382:microbiology*; D013210:Staphylococcus / Q000302:isolation & purification*