Early retinal activity and visual circuit development.
Does spontaneous retinal activity prior to vision play a role in the establishment of visual maps? In this issue of Neuron, two separate papers by Huberman et al. and Hooks and Chen demonstrate a role for early spontaneous retinal activity in the establishment of ocular dominance columns and synaptic refinement at retinogeniculate synapses.
Del Rio
Tony
T
Neurobiology Section 0357, Division of Biological Sciences, University of California, San Diego, 3125A Pacific Hall, 9500 Gilman Drive, La Jolla, California 92093, USA.
Feller
Marla B
MB
D000200:Action Potentials / Q000502:physiology; D000818:Animals; D002454:Cell Differentiation / Q000502:physiology*; D005829:Geniculate Bodies / Q000166:cytology / Q000254:growth & development; D006801:Humans; D009473:Neuronal Plasticity / Q000502:physiology; D009474:Neurons / Q000166:cytology / Q000502:physiology*; D012160:Retina / Q000166:cytology / Q000254:growth & development*; D009435:Synaptic Transmission / Q000502:physiology*; D014793:Visual Cortex / Q000166:cytology / Q000254:growth & development; D014795:Visual Pathways / Q000166:cytology / Q000254:growth & development*