[The distribution and pathogen of bacteria infection in patients after liver transplantation].
OBJECTIVE
To find out the epidemiology of bacteria infection after orthotopic liver transplantation (OLT).


METHODS
Postoperative bacteria infection of 451 OLT cases were retrospectively analyzed.


RESULTS
Bacteria infection were detected in 239 OLT cases, and the infection rate was 52.9%. Sum up to 304 bacilli lines were separated from all above cases. Among them, the detectable Gram-positive bacilli (G(+)) accounted for 59.9% (182/304), while Gram-negative bacilli (G(-)) accounted for 40.2% (122/304). The impressionable organ were respiratory tract and bile duct, which occupying 81.5% (248/304) and 15.1% (46/304) among all infective cases respectively. The main infected strain were G(+) bacteria in respiratory tract, account for 65.3%; while G(-) bacteria were mainly in bile duct, account for 60.9%. There was significant difference between each other (P = 0.018).


CONCLUSIONS
The bacteria infection rate was high after OLT, and the main infected strain was the G(+) bacteria. Most fo them were the opportunistic pathogenic bacteria and the antibiotic multi-resistant bacteria. The bacteria category was significantly related to the infected tissue, according to which we could adopt corresponding antibacterial approach.
Cai
Chang-jie
CJ
Organ Transplantation Center, Third Affiliated Hospital, Sun Sen-Yat University, Guangzhou 510630, China.
Lu
Min-qiang
MQ
Li
Min-ru
MR
Yang
Yang
Y
Yi
Hui-min
HM
Xu
Chi
C
Li
Hua
H
Yi
Shu-hong
SH
Wang
Gen-shu
GS
Chen
Gui-hua
GH
D000293:Adolescent; D000328:Adult; D000368:Aged; D001424:Bacterial Infections / Q000209:etiology / Q000382:microbiology*; D001649:Bile Duct Diseases / Q000209:etiology / Q000382:microbiology*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006090:Gram-Negative Bacteria / Q000302:isolation & purification; D006094:Gram-Positive Bacteria / Q000302:isolation & purification; D006801:Humans; D007223:Infant; D016031:Liver Transplantation / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D012141:Respiratory Tract Infections / Q000209:etiology / Q000382:microbiology*; D012189:Retrospective Studies