Chinmo and neuroblast temporal identity.
Although spatial patterning during embryonic development is well characterized, a corresponding framework for temporal patterning has not been established. In this issue, Zhu et al. (2006) identify the Chinmo protein as conferring temporal identity on the neural progeny of Drosophila neuroblasts, revealing appealing parallels with spatial patterning.
Doe
Chris Q
CQ
Institute of Neuroscience, Howard Hughes Medical Institute,University of Oregon, Eugene, 97403, USA. cdoe@uoneuro.uoregon.edu
D000818:Animals; D001921:Brain / Q000166:cytology* / Q000378:metabolism; D002454:Cell Differentiation; D019070:Cell Lineage; D004330:Drosophila / Q000166:cytology / Q000254:growth & development*; D029721:Drosophila Proteins / Q000378:metabolism*; D007814:Larva / Q000166:cytology / Q000378:metabolism; D009024:Morphogenesis; D009474:Neurons / Q000378:metabolism*; D014176:Protein Biosynthesis; D013997:Time Factors; D019076:Transgenes
D029721:Drosophila Proteins