title: Bradyarrhythmias during use of the AngioJet system.
abstract: The AngioJet system is an effective thrombectomy device, but it may cause chest discomfort and provoke bradyarrhythmias that range from mild bradycardia to asystole. The cause of AngioJet-induced bradyarrhythmia is unknown, although several hypotheses have attempted to explain the phenomenon. Herein several cases will be described, followed by a review of the relevant literature. The literature review suggests that the cause may be related to the effects of the hydrodynamic jets on stretch-activated receptors present on the vascular endothelium, and that pretreatment with gadolinium or streptomycin might prevent activation of these receptors.
authors.affiliation: Department of Radiology, University of Arizona Health Sciences Center, 1501 North Campbell Avenue, Tucson, AZ 85724-5067, USA.
authors.forename: Dan
authors.initials: D
authors.lastname: Dwarka
authors.forename: Stephanie A
authors.initials: SA
authors.lastname: Schwartz
authors.forename: Stephen H
authors.initials: SH
authors.lastname: Smyth
authors.forename: Michael J
authors.initials: MJ
authors.lastname: O'Brien
mesh_terms: D000368:Aged; D001919:Bradycardia / Q000209:etiology*; D004487:Edema; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011655:Pulmonary Embolism / Q000601:surgery*; D013119:Spinal Cord Injuries / Q000150:complications / Q000601:surgery; D017131:Thrombectomy / Q000009:adverse effects* / Q000295:instrumentation; D014057:Tomography, X-Ray Computed; D002583:Uterine Cervical Neoplasms / Q000150:complications / Q000473:pathology; D020246:Venous Thrombosis / Q000000981:diagnostic imaging / Q000601:surgery*