title: The Baylis-Hillman approach to quinoline derivatives.
abstract: Baylis-Hillman reactions of 2-nitrobenzaldehydes with various activated alkenes afford adducts that undergo reductive cyclisation to quinoline derivatives. The chemo- and regioselectivity of cyclisation appears to be influenced by the choice of both the substrate and the reagent system, and competing reactions have been observed.
authors.affiliation: Department of Chemistry, Rhodes University, Grahamstown, 6140, South Africa.
authors.forename: Oluwole B
authors.initials: OB
authors.lastname: Familoni
authors.forename: Phindile J
authors.initials: PJ
authors.lastname: Klaas
authors.forename: Kevin A
authors.initials: KA
authors.lastname: Lobb
authors.forename: Vusumzi E
authors.initials: VE
authors.lastname: Pakade
authors.forename: Perry T
authors.initials: PT
authors.lastname: Kaye
mesh_terms: D008956:Models, Chemical; D011804:Quinolines / Q000138:chemical synthesis* / Q000737:chemistry*
chemical_list: D011804:Quinolines; C037219:quinoline