[Studies on the chemical constituents in herb of Ranunculus japonicus].
OBJECTIVE
To isolate and determine the chemical constituents from Ranunculus japonicus.


METHODS
Compounds were isolated by column chromatography, and identified by MS, NMR data.


RESULTS
Nine compounds were obtained andelucidated as scoparone (1), tricin (2), protocatechuic acid (3), luteolin (4), anemonin (5), scopoletin (6), 5-hydroxy-6, 7-dimethoxyflavone (7), 5-hydroxy-7, 8-dimethoxyflavone (8), ternatolide (9), respectively.


CONCLUSIONS
Compounds 1-9 were isolated from R. japonicus for the first time while compounds 7, 8 were separated from Ranunculus genus first time.
Zheng
Wei
W
Department of Traditional Chinese Medicine and Natural Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangdzhou 310031, China.
Zhou
Chang-xin
CX
Zhang
Shui-li
SL
Weng
Lin-jia
LJ
Zhao
Yu
Y
D003374:Coumarins / Q000737:chemistry / Q000302:isolation & purification; D005419:Flavonoids / Q000737:chemistry / Q000302:isolation & purification*; D010946:Plants, Medicinal / Q000737:chemistry*; D031947:Ranunculus / Q000737:chemistry*
D003374:Coumarins; D005419:Flavonoids; C035064:5-hydroxy-7,8-dimethoxyflavone; C017769:tricin; C521856:mosloflavone; C018145:scoparone