title: Central obesity and dietary intake in HIV/AIDS patients.
abstract: OBJECTIVE
  To assess the association between dietary intake and central obesity among people living with HIV/AIDS and receiving highly active antiretroviral therapy.
  
  
  METHODS
  A cross-sectional study was conducted involving 223 adult individuals in the city of São Paulo city in 2002. The study population was classified according to central obesity, defined as waist-to-hip ratio >0.95 for men and >0.85 for women. The dietary variables studied were energy consumption (in calories and calories/kilo of body weight), macronutrients (in grams and % of energy intake), total fiber (grams) and fruit and vegetables intake (grams). The potential confounders examined were sex, skin color, age, schooling, income, body mass index, physical activity, smoking habits, peripheral CD4+ T lymphocyte count and length of protease inhibitor use. The multiple logistic regression model was performed in order to evaluate the association between central obesity and dietary intake.
  
  
  RESULTS
  The prevalence of central obesity was 45.7% and it was associated with greater consumption of lipids: for every increase of 10g of lipid intake the odds of central obesity increased 1.28 times. Carbohydrate consumption showed negative association (OR=0.93) with central obesity after adjustment for control variables.
  
  
  CONCLUSIONS
  The results suggest that the amount of carbohydrates and lipids in the diet, regardless of total energy intake, may modify the chance of developing central obesity in the studied population. Nutritional interventions may be beneficial for preventing central obesity among HIV/AIDS patients.
authors.affiliation: Departamento de Nutrição, Faculdade de Saúde Pública, Universidade de São Paulo, São Paulo, Brasil. constant@usp.br
authors.forename: Patrícia Constante
authors.initials: PC
authors.lastname: Jaime
authors.forename: Alex Antonio
authors.initials: AA
authors.lastname: Florindo
authors.forename: Maria do Rosário Dias de Oliveira
authors.initials: Mdo R
authors.lastname: Latorre
authors.forename: Aluísio Augusto Cotrim
authors.initials: AA
authors.lastname: Segurado
mesh_terms: D050153:Abdominal Fat / Q000502:physiology*; D000163:Acquired Immunodeficiency Syndrome / Q000188:drug therapy / Q000503:physiopathology; D000328:Adult; D019380:Anti-HIV Agents / Q000627:therapeutic use; D023241:Antiretroviral Therapy, Highly Active; D015992:Body Mass Index; D001938:Brazil / Q000453:epidemiology; D004040:Dietary Carbohydrates / Q000008:administration & dosage; D004041:Dietary Fats / Q000009:adverse effects*; D004812:Epidemiologic Methods; D005260:Female; D015658:HIV Infections / Q000188:drug therapy / Q000503:physiopathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000453:epidemiology* / Q000378:metabolism; D012959:Socioeconomic Factors; D049629:Waist-Hip Ratio
chemical_list: D019380:Anti-HIV Agents; D004040:Dietary Carbohydrates; D004041:Dietary Fats