[Therapeutic effect of deoxyribonucleotidum on acute viral myocarditis].
OBJECTIVE
To evaluate the therapeutic efficacy of deoxyribonucleotidum in treatment of acute viral myocarditis.


METHODS
Eighty-eight patients with acute viral myocarditis were randomized equally into therapeutic group and control group. Patients in the control group were treated with routine treatment and those in the therapeutic group were given deoxyribonucleotidum in addition to routine treatment. After 4 weeks, the total efficacy rate and median time of symptom disappearance were compared between the two groups.


RESULTS
The total efficacy rate in the control and therapeutic groups was 79.54% and 95.45% (P=0.049), and the median time of symptom disappearance was 9.5 days and 6.5 days, respectively (P=0.035). Hypotension and mild dizziness were found in 2 patients in the therapeutic group without other severe side effects.


CONCLUSIONS
Deoxyribonucleotidum can improve the therapeutic effect for acute viral myocarditis.
Zeng
Zhi-huan
ZH
Department of Cardiology, First Affiliated Hospital, Gangdong College of Pharmacy, Guangzhou 510080, China.
Lei
Da
D
Zhou
Wan-xing
WX
D000293:Adolescent; D000328:Adult; D003854:Deoxyribonucleotides / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009205:Myocarditis / Q000188:drug therapy*; D016896:Treatment Outcome; D014777:Virus Diseases / Q000188:drug therapy*
D003854:Deoxyribonucleotides