[Effects of shexiang baoxin pill on carotid atheromatous plaque].
OBJECTIVE
To study the effects of Shexiang Baoxin Pill (SBP) in treating carotid atherosclerosis (CAS).


METHODS
Forty-one CAS patients were randomly assigned to 2 groups, the SBP group (31 cases) treated with SBP plus routine treatment and the control group (10 cases) with routine treatment only. Both were treated for 6 months. The changes of carotid atheromatous plaque (CAP), C reactive protein (CRP), fibrinogen (FIB), D-dimer and blood lipids, etc. were observed.


RESULTS
After treatment, average number, total scores and area of plaque, as well as levels of CRP, FIB and D-dimer decreased significantly in the SBP group (P < 0.05 or P < 0.01), and were lower than those in the control group after treatment respectively (P < 0.05). No severe adverse reaction occurred in both groups.


CONCLUSIONS
SBP is a safe and effective remedy for treatment of CAS.
Hong
Yong-dun
YD
The First Affiliated Hospital of Guangzhou University of TCM, Guangzhou. hongyongdun@163.com
Wu
Hui
H
Zhao
Ping
P
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002340:Carotid Artery Diseases / Q000000981:diagnostic imaging / Q000188:drug therapy*; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D008517:Phytotherapy; D013607:Tablets; D016896:Treatment Outcome; D014463:Ultrasonography
D004365:Drugs, Chinese Herbal; D013607:Tablets; C526712:shexiang baoxin