title: Risk of noncardiac surgery after coronary drug-eluting stent implantation.
abstract: We examined the records of 38 patients who underwent 41 major and 18 minor noncardiac surgeries after successful drug-eluting stent (DES) implantation (57% sirolimus-eluting stents and 43% paclitaxel-eluting stents) at the Dallas Veterans Affairs Medical Center from April 2003 to January 2006. The mean patient age was 62 +/- 9 years, and all patients were men. A total of 41 major noncardiac surgeries (34% abdominal, 22% vascular, 17% genitourinary, and 27% other) were performed in 28 patients a median of 260 days after DES implantation. Also, 18 minor noncardiac surgeries (44% skin surgery, 44% injections, and 12% other) were performed in 10 patients a median of 297 days after DES implantation. No major adverse cardiac events or death occurred during or after the 41 major (0%, 95% confidence interval 0% to 9%) and 18 minor noncardiac (0%, 95% confidence interval 0% to 19%) surgeries. In conclusion, although our data were limited by the small sample size, they suggest a low risk of major cardiac complications in patients undergoing noncardiac surgery after coronary DES implantation.
authors.affiliation: Division of Internal Medicine, University of Texas Southwestern Medical School, Dallas, Texas, USA.
authors.forename: P Alexander
authors.initials: PA
authors.lastname: Compton
authors.forename: Ahmad A
authors.initials: AA
authors.lastname: Zankar
authors.forename: Adebola O
authors.initials: AO
authors.lastname: Adesanya
authors.forename: Subhash
authors.initials: S
authors.lastname: Banerjee
authors.forename: Emmanouil S
authors.initials: ES
authors.lastname: Brilakis
mesh_terms: D000368:Aged; D023921:Coronary Stenosis / Q000628:therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D017239:Paclitaxel / Q000627:therapeutic use; D012307:Risk Factors; D020123:Sirolimus / Q000627:therapeutic use; D015607:Stents; D013514:Surgical Procedures, Operative / Q000706:statistics & numerical data*; D013781:Texas / Q000453:epidemiology; D016896:Treatment Outcome
chemical_list: D017239:Paclitaxel; D020123:Sirolimus