title: Reactivation of 2 genetically distinct varicella-zoster viruses in the same individual.
abstract: Varicella-zoster viruses recovered from 2 episodes of herpes zoster in an immunocompetent man were found to be different genotypes. The fact that the 2 isolates came from the same individual was confirmed by DNA fingerprinting. Immunity following chickenpox may not always protect against systemic reinfection. This finding raises questions about varicella-zoster virus pathogenesis and may have an impact on public health policy.
authors.affiliation: Skin Virus Laboratory, Centre for Infectious Diseases Research, Barts and the London School of Medicine and Dentistry, London, E1 2AT, United Kingdom.
authors.forename: Y
authors.initials: Y
authors.lastname: Taha
authors.forename: F T
authors.initials: FT
authors.lastname: Scott
authors.forename: S P
authors.initials: SP
authors.lastname: Parker
authors.forename: D
authors.initials: D
authors.lastname: Syndercombe Court
authors.forename: M L
authors.initials: ML
authors.lastname: Quinlivan
authors.forename: J
authors.initials: J
authors.lastname: Breuer
mesh_terms: D000328:Adult; D004279:DNA, Viral / Q000032:analysis; D014644:Genetic Variation; D006562:Herpes Zoster / Q000276:immunology / Q000821:virology*; D014645:Herpesvirus 3, Human / Q000235:genetics* / Q000502:physiology; D006801:Humans; D007121:Immunocompetence; D008297:Male; D014775:Virus Activation
chemical_list: D004279:DNA, Viral