Management of heart failure in the elderly: recommendations from the French Society of Cardiology (SFC) and the French Society of Gerontology and Geriatrics (SFGG).
Heart failure, a frequent disease in the elderly, has a pejorative prognosis. Clinical diagnosis is complicated by atypical or difficult-to-interpret symptoms and by the concomitant presence of other diseases, particularly cognitive impairment, neurological disorders and diseases of the musculoskeletal system. Among the additional investigations, echocardiography remains underused. Impairment of diastolic left ventricular function is frequent. The usual laboratory tests must include calculation of the creatinine clearance, which is indispensable for dosage adjustment of certain drugs (ACE inhibitors, digoxin, spironolactone). The value of plasma natriuretic peptide assays as diagnostic tools has not been determined in elderly or very elderly populations and the plasma B-type natriuretic peptide increases with age. Comprehensive geriatric assessment is essential in order to screen for concomitant diseases and determine the patient's degree of dependence. The general objectives of treatment remain applicable to the elderly subject: improvement in the quality of life, reduction of mortality and the number and duration of hospitalisations, and slowing disease progression. In the frail elderly subject, symptom alleviation is to be the primary objective. In the absence of specific studies on elderly or very elderly subjects, most of the recommendations have been extrapolated from the data based on the evidence generated in younger populations. The dietary rules are to be more flexible than those used for younger subjects, particularly in order to prevent the risk of denutrition induced by strict salt-free diets. Special precautions for the use of heart failure drugs are due to comorbidities and the pharmacokinetic and pharmacodynamic changes related to aging. Drugs dosage increase is to be cautious and carefully monitored for adverse reactions. The therapeutic programmes in which multidisciplinary teams are involved reduce the number and duration of hospitalisations and the costs generated by the disease.
Komajda
M
M
Department of Cardiology, Pitié Salpêtrière Hospital, 47/83 boulevard de l'Hôpital, 75013 Paris, France. michel.komajda@psl.ap-hop-paris.fr
Hanon
O
O
Aupetit
J F
JF
Benetos
A
A
Berrut
G
G
Emeriau
J P
JP
Friocourt
P
P
Galinier
M
M
De Groote
P
P
Jondeau
G
G
Jourdain
P
P
Forette
F
F
D000368:Aged; D002309:Cardiology / Q000592:standards*; D003937:Diagnosis, Differential; D005602:France; D015577:Geriatric Assessment; D005853:Geriatrics / Q000592:standards*; D006299:Health Services for the Aged / Q000592:standards*; D006333:Heart Failure / Q000175:diagnosis / Q000473:pathology / Q000628:therapy*; D006801:Humans; D010818:Practice Patterns, Physicians'; D012955:Societies, Medical