title: Acute and long-term results of bifurcation stenting (from the Coroflex Registry).
abstract: Angioplasty of bifurcation lesions represents a continuing challenge. A total of 421 consecutive patients were prospectively followed in a registry on bifurcation stenting with a high-end bare metal stent (Coroflex, BBraun, Berlin, Germany), allowing side branch percutaneous transluminal coronary angioplasty through the stent struts without distraction of the main vessel stent from the vessel wall or other distortions. This approach obviated the 2-wire technique and kissing balloons. Detailed data, including lesion location, stenosis morphology, procedural success, and hospital and follow-up major adverse cardiac events (MACEs; acute myocardial infarction, death, revascularization, hospitalization due to angina), were collected from 6 European centers. Of the patients, 60% had stable angina, 23% had unstable angina pectoris/non-ST-elevation myocardial infarction, and 17% had ST-elevation myocardial infarction. In 17% of patients, the main vessel alone was stented; in 71%, stenting of the main vessel was complemented by side branch percutaneous transluminal coronary angioplasty. Technical success (residual stenosis <50%) in the 2 branches was achieved in 90% (main vessel in 99%). The rate of MACEs at discharge was 2%. After 6 months, 17% of patients had undergone target lesion revascularization or coronary artery bypass grafting. The total 6-month MACE rate was 22%. In conclusion, successful bifurcation stenting with a low MACE rate is possible in most patients using a simplified approach with a dedicated high-end bare metal stent.
authors.affiliation: ukb Academic Teaching Hospital, Berlin, Germany.
authors.forename: Sascha
authors.initials: S
authors.lastname: Rux
authors.forename: Steffen
authors.initials: S
authors.lastname: Sonntag
authors.forename: Ralph
authors.initials: R
authors.lastname: Schulze
authors.forename: Matthias
authors.initials: M
authors.lastname: Rau
authors.forename: Frank
authors.initials: F
authors.lastname: Weber
authors.forename: Holger
authors.initials: H
authors.lastname: Mühling
authors.forename: Angelo
authors.initials: A
authors.lastname: Cioppa
authors.forename: Franz Xaver
authors.initials: FX
authors.lastname: Kleber
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000787:Angina Pectoris / Q000453:epidemiology / Q000209:etiology*; D015906:Angioplasty, Balloon, Coronary / Q000009:adverse effects; D023921:Coronary Stenosis / Q000150:complications / Q000628:therapy*; D016757:Death, Sudden, Cardiac / Q000453:epidemiology / Q000209:etiology*; D004867:Equipment Design; D005060:Europe / Q000453:epidemiology; D005260:Female; D005500:Follow-Up Studies; D017052:Hospital Mortality; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000453:epidemiology / Q000209:etiology*; D010343:Patient Admission / Q000706:statistics & numerical data; D015995:Prevalence; D011446:Prospective Studies; D012086:Reoperation; D015607:Stents / Q000009:adverse effects; D013997:Time Factors; D016896:Treatment Outcome