Risk factors of first peritonitis episode in Thai CAPD patients.
BACKGROUND
Peritonitis is a major complication of continuous ambulatory peritoneal dialysis (CAPD) patients. Information on the specific risk of peritonitis is important in reducing this common complication.


METHODS
A single center retrospective cohort study was done to assess time to first peritonitis event and risk factors in Thai CAPD population.


RESULTS
Between January 1995 and December 2005, 322 incident CAPD patients were recruited for the present study. During the study period of 4,281 patient-months, 198 episodes of first peritonitis were recorded. The median peritonitis-free time was 13.7 months. A Cox regression model showed that an increase in level of baseline albumin and hematocrit by 1 g/dL and 1% would decrease risk of peritonitis by 27% and 3%, respectively (hazard ratio (95%CI): 0.73 (0.59-0.91) and 0.97 (0.94-1.00)). A neutral effect of self and caregiver performer was observed in the present study.


CONCLUSIONS
The present study confirmed the susceptibility of hypoalbuminemia and anemia to peritonitis. Awareness of particular risk groups should be achieved to prevent peritonitis.
Sirivongs
Dhavee
D
Division of Nephrology, Department of Medicine, Faculty of Medicine, Khon Kaen University, Thailand. dhavee@kku.ac.th
Pongskul
Cholatip
C
Keobounma
Thathsalang
T
Chunlertrith
Darunee
D
Sritaso
Kanokkorn
K
Johns
Jeff
J
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015331:Cohort Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010531:Peritoneal Dialysis, Continuous Ambulatory / Q000009:adverse effects*; D010538:Peritonitis / Q000209:etiology* / Q000401:mortality; D016016:Proportional Hazards Models; D012189:Retrospective Studies; D012307:Risk Factors; D015996:Survival Rate; D013785:Thailand