title: [Analysis and quality assessment standard of heavy metals and arsenic in Rhizoma et Radix Notopterygii from different localities].
abstract: OBJECTIVE
  Five heavy metals (Hg, Cu, Cd, Pb, Cr) and arsenic (As) contents in 57 samples of from 19 localities in Sichuan, Qinghai and Gansu of Rhizoma et Radix Notopterygii sourcing from two plants Notoperygium incusum and N. forbesii has been analyzed to evaluate the content standard of heavy metal and arsenic for drafting the herbal medicine quality.
  
  
  METHODS
  ICP-AES method was applied to determine As, Cu, Cd, Pb, Cr and CAAS method was applied to determine Hg.
  
  
  RESULTS
  Hg can not be determined through CAAS, and little Pb was determined except in limited N. forbesii samples from certain sites, while the contents of Cu in most samples are higher than 20 mg x kg(-1). As in N. forbesii samples, and Cd in N. incisum samples are higher or approximate the limitation of related standard of medicinal plants and production. Cr varies from different localities, ranging from 0.48 to 8.36 mg x kg(-1) for N. incisum and 1.44-8.03 mg x kg(-1) for N. forbesii.
  
  
  CONCLUSIONS
  Referring to the related standards of medicine and vegetable, the heavy metals and arsenic contents of Rhizoma et Radix Notopterygii samples from traditional producing areas are confirmed the propositional standard, i. e., Pb < or = 5.0 mg x kg(-1), Cd < or = 0.3 mg x kg(-1), Hg < or = 0.2 mg x kg(-1), Cu < or = 28.0 mg x kg(-1), As < or = 2.0 mg x kg(-1), and Cr < or = 1.0 mg x kg(-1). Of these five heavy metals, Cu is much over the limitation standard, which suggested that GAP base of Rhizoma et Radix Notopterygii must be selected in lower Cu environmental condition in main producing area.
authors.affiliation: College of Life Science, Sichuan University, Chengdu 610065, China.
authors.forename: Shun-yuan
authors.initials: SY
authors.lastname: Jiang
authors.forename: Hui
authors.initials: H
authors.lastname: Sun
authors.forename: Xiu-chen
authors.initials: XC
authors.lastname: Wu
authors.forename: Yi
authors.initials: Y
authors.lastname: Zhou
authors.forename: Xiao-jun
authors.initials: XJ
authors.lastname: Ma
authors.forename: Rui
authors.initials: R
authors.lastname: Wu
mesh_terms: D019661:Apiaceae / Q000737:chemistry* / Q000145:classification; D001151:Arsenic / Q000032:analysis*; D002104:Cadmium / Q000032:analysis; D002681:China; D002857:Chromium / Q000032:analysis; D003300:Copper / Q000032:analysis; D017753:Ecosystem; D019216:Metals, Heavy / Q000032:analysis*; D018517:Plant Roots / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry* / Q000145:classification; D011786:Quality Control; D027343:Rhizome / Q000737:chemistry
chemical_list: D019216:Metals, Heavy; D002104:Cadmium; D002857:Chromium; D003300:Copper; D001151:Arsenic