title: [Advances in caffeoylquinic acid research].
abstract: This paper reviewed updated research progresses of caffeoylquinic acids both in phytochemical and pharmacological aspects. The resources, distribution as well as the chemical structures of monocaffeoylquinic acids, dicaffeoylquinic acids, tricaffeoylquinic acids and multicaffeoylquinic acids are conclusively analyzed. The reviewed pharmacological investigations indicated that the caffeoylquinic acids exhibited significant activities such as anti-oxidation, anti-inflammation, enzyme inhibition, hypatoprotective and anti-PAF effects. The broad distribution and the remarkably pharmacological activities of these natural phenolic acids indicated their potential in the discovery and development of new natural drugs.
authors.affiliation: College of Pharmaceutical Science, Zhejiang University, Hangzhou 310031, China. dryuzhao@zju.edu.cn
authors.forename: Yu
authors.initials: Y
authors.lastname: Zhao
authors.forename: Jun
authors.initials: J
authors.lastname: Zhao
authors.forename: Xiang-ping
authors.initials: XP
authors.lastname: Li
authors.forename: Chang-xin
authors.initials: CX
authors.lastname: Zhou
authors.forename: Han-dong
authors.initials: HD
authors.lastname: Sun
authors.forename: Xiao-jiang
authors.initials: XJ
authors.lastname: Hao
authors.forename: Pei-gen
authors.initials: PG
authors.lastname: Xiao
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000302:isolation & purification / Q000494:pharmacology; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000302:isolation & purification / Q000494:pharmacology*; D000975:Antioxidants / Q000302:isolation & purification / Q000494:pharmacology*; D000998:Antiviral Agents / Q000302:isolation & purification / Q000494:pharmacology; D002726:Chlorogenic Acid / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D004791:Enzyme Inhibitors / Q000302:isolation & purification / Q000494:pharmacology; D006801:Humans; D018515:Plant Leaves / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D011801:Quinic Acid / Q000031:analogs & derivatives* / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology
chemical_list: D000900:Anti-Bacterial Agents; D000894:Anti-Inflammatory Agents, Non-Steroidal; D000975:Antioxidants; D000998:Antiviral Agents; D004791:Enzyme Inhibitors; C472707:caffeoylquinic acid; D011801:Quinic Acid; D002726:Chlorogenic Acid