Interactions between nitric oxide, oxygen, reactive oxygen species and reactive nitrogen species.
ROS (reactive oxygen species) and RNS (reactive nitrogen species) are central to the innate immunity that protects us from infection, but also contribute to degenerative diseases and possibly aging. However, ROS and RNS are increasingly recognized to contribute to physiological signalling. This review briefly describes the main interactions between ROS and RNS and shows how their origins, chemistry, metabolism and biological actions are intimately linked.
Brown
G C
GC
Department of Biochemistry, University of Cambridge, Tennis Court Road, Cambridge CB2 1QW, UK. gcb@mole.bio.cam.ac.uk
Borutaite
V
V
D016923:Cell Death; D002455:Cell Division; D002470:Cell Survival; D006801:Humans; D009569:Nitric Oxide / Q000378:metabolism*; D010101:Oxygen Consumption; D026361:Reactive Nitrogen Species / Q000378:metabolism*; D017382:Reactive Oxygen Species / Q000378:metabolism*; D013481:Superoxides / Q000378:metabolism
D026361:Reactive Nitrogen Species; D017382:Reactive Oxygen Species; D013481:Superoxides; D009569:Nitric Oxide