[Affection of Bushen Shengjing pill on NO and NOS in testicle and ante-oxidization of rat with spermatogenic cell injury].
OBJECTIVE
Discuss the functional mechanism of treating male infertility with Bushen Shengjing pill (BS).


METHODS
Fill the SD rat with adenine so as to injure the germ cell which will produce the model rat with kidney yang deficiency. Measure the activity of SOD and NOS, the amount of NO and MDA in the testicle.


RESULTS
BS can promote the activity of SOD, reduce the activity of NOS and the amount of NO and MDA.


CONCLUSIONS
BS has the function of protecting the germ cell which is closely related to the function that the pill can promote the activity of SOD, reduce the activity of NOS and the amount of NO and MDA.
Yang
A-min
AM
Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100700, China. amwds@163.com
Li
Yue-qing
YQ
Li
Hai-song
HS
Song
Chong-shun
CS
Ren
Ying
Y
Yin
Jun-xiang
JX
D000225:Adenine; D000818:Animals; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification / Q000494:pharmacology*; D005303:Fertility Agents, Male / Q000494:pharmacology; D007674:Kidney Diseases / Q000139:chemically induced / Q000378:metabolism*; D008297:Male; D008315:Malondialdehyde / Q000378:metabolism; D009569:Nitric Oxide / Q000378:metabolism*; D019001:Nitric Oxide Synthase / Q000378:metabolism*; D010946:Plants, Medicinal / Q000737:chemistry; D011897:Random Allocation; D051381:Rats; D017207:Rats, Sprague-Dawley; D013091:Spermatogenesis / Q000187:drug effects; D013482:Superoxide Dismutase / Q000378:metabolism; D013737:Testis / Q000378:metabolism; D016711:Yang Deficiency / Q000139:chemically induced / Q000378:metabolism*
D004338:Drug Combinations; D004365:Drugs, Chinese Herbal; D005303:Fertility Agents, Male; D009569:Nitric Oxide; D008315:Malondialdehyde; D019001:Nitric Oxide Synthase; D013482:Superoxide Dismutase; D000225:Adenine