title: Expression of RhoB in the developing Xenopus laevis embryo.
abstract: Rho GTPases are signaling components that participate to the control of cell morphology, adhesion and motility through the regulation of F-actin cytoskeleton dynamics. In this paper, we report the identification of RhoB in Xenopus laevis (XRhoB) and its expression pattern during early development. Whole-mount in situ hybridization analysis indicated that XrhoB is expressed at high levels in the dorsal marginal zone early in gastrula and in the dorsal midline at later stages. At mid-neurula stages, XrhoB expression extends to the central nervous system, presomitic mesoderm and somites. Later during development, rhoB mRNA is detected in the eyes, the migrating neural crest cells as well as the dorso-lateral part of the somites.
authors.affiliation: Centre de Recherches en Biochimie Macromoléculaire, FRE 2593 CNRS, 1919 route de Mende, 34293 Montpellier, France.
authors.forename: Emmanuel
authors.initials: E
authors.lastname: Vignal
authors.forename: Pascal
authors.initials: P
authors.lastname: de Santa Barbara
authors.forename: Linda
authors.initials: L
authors.lastname: Guémar
authors.forename: Jean Marc
authors.initials: JM
authors.lastname: Donnay
authors.forename: Philippe
authors.initials: P
authors.lastname: Fort
authors.forename: Sandrine
authors.initials: S
authors.lastname: Faure
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D004625:Embryo, Nonmammalian / Q000378:metabolism; D020224:Expressed Sequence Tags; D018507:Gene Expression Regulation, Developmental; D017403:In Situ Hybridization; D008969:Molecular Sequence Data; D010802:Phylogeny; D016415:Sequence Alignment; D029867:Xenopus Proteins / Q000737:chemistry / Q000235:genetics*; D014982:Xenopus laevis / Q000196:embryology* / Q000235:genetics; D020743:rhoB GTP-Binding Protein / Q000737:chemistry / Q000235:genetics*
chemical_list: D029867:Xenopus Proteins; D020743:rhoB GTP-Binding Protein