Disseminated Mycobacterium avium complex infection in an immunocompetent pregnant woman.
BACKGROUND
Disseminated mycobacterium avium complex (MAC) occurs mainly in immunocompromised hosts, which is associated with abnormal cellular immunity.


METHODS
A 26-year-old pregnant woman presented with fever and general weakness. Miliary lung nodules were noted on chest X-ray. Under the impression of miliary tuberculosis, anti-tuberculosis medication was administered. However, the patient was not improved. Further work-up demonstrated MAC in the sputum and placenta. The patient was treated successfully with clarithromycin-based combination regimen.


CONCLUSIONS
This appears to be the first case of disseminated MAC in an otherwise healthy pregnant woman. Clinicians should be alert for the diagnosis of MAC infection in diverse clinical conditions.
Song
Joon Young
JY
Division of Infectious Diseases, Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea. infection@medimail.co.kr
Park
Cheong Won
CW
Kee
Sae Yoon
SY
Choi
Won Seok
WS
Kang
Eun Young
EY
Sohn
Jang Wook
JW
Kim
Woo Joo
WJ
Kim
Min Ja
MJ
Cheong
Hee Jin
HJ
D000328:Adult; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D000995:Antitubercular Agents / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007121:Immunocompetence / Q000276:immunology*; D008171:Lung Diseases / Q000382:microbiology / Q000473:pathology; D015270:Mycobacterium avium-intracellulare Infection / Q000175:diagnosis / Q000188:drug therapy; D010920:Placenta / Q000382:microbiology; D011241:Prednisone / Q000627:therapeutic use; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000276:immunology* / Q000382:microbiology*
D000893:Anti-Inflammatory Agents; D000995:Antitubercular Agents; D011241:Prednisone