The clinicopathology and outcome of post-infectious glomerulonephritis: experience in 36 adults.
Post-infectious glomerulonephritis is one of the most common causes of acute glomerulonephritis. A retrospective study of post-infectious glomerulonephritis at King Chulalongkorn Memorial Hospital, Thailand was performed from January 1999 to December 2005. Among thirty six patients, eight cases were post-streptococcal glomerulonephritis and twenty eight cases were post non-streptococcal Glomerulo Nephritis (GN). Most cases present with edema, hypertension, gross hematuria and nephrotic-range proteinuria. C3 and CH50 commonly were low. Post-streptococcal glomerulonephritis had more aggressive pathology compared to the others. However the long term outcome was excellent. In the present study the authors found ESRD in only 14.3% (4 out of 28 cases) that reflects the excellent prognosis of post-infectious glomerulonephritis. Of interest, all of the ESRD patients were caused by post non-Streptococcal GN. Even though, no statistic was achieved; it might reflect the aggressiveness of non-Streptococcal pathogen.
Srisawat
Nattachai
N
Department of Medicine, Faculty of Medicine, Chulalongkorn University Hospital, Bangkok, Thailand.
Aroonpoonsub
Laor
L
Lewsuwan
Songkiat
S
Kanjanabuch
Talengsak
T
Avihingsanon
Yingyos
Y
Praditpornsilpa
Kearkiat
K
Tungsanga
Kraing
K
Chusil
Sawaluk
S
Eiam-Ong
Somchai
S
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D005921:Glomerulonephritis / Q000150:complications* / Q000401:mortality; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012189:Retrospective Studies; D013290:Streptococcal Infections / Q000188:drug therapy* / Q000209:etiology*; D015996:Survival Rate; D013785:Thailand; D016896:Treatment Outcome