[Mechanisms of the intracellular activities of thyroid gland hormones].
Function of thyroid hormones affecting broad spectrum of various biochemical and molecular biology reactions in organisms is unimaginable without fully functional nuclear receptors. On account of this fact, research on the role and function of thyroid hormone receptors that play a role as thyroid hormone inducible transcription factors, belongs to dynamically developing branches of molecular endocrinology. In organism, full functionality of thyroid hormone receptors in the form of heterodimer with nuclear 9-cis retinoic acid receptor is essential for biological effects of 3,5,3'-triiodothyronine.
Brtko
J
J
Laboratórium molekulárnej endokrinológie, Ustav experimentálnej endokrinológie SAV, Bratislava, Slovenská republika. julius.brtko@savba.sk
D006801:Humans; D011988:Receptors, Thyroid Hormone / Q000502:physiology; D013963:Thyroid Hormones / Q000737:chemistry / Q000494:pharmacology / Q000502:physiology*
D011988:Receptors, Thyroid Hormone; D013963:Thyroid Hormones