[Research progress in Laggera medicinal plants].
This paper reviewed the worldwide research progresses of the genus Laggera both on phytochemical and pharmacological work in the past few decades. The main secondary metabolites of this genus are proved to be sesquitepenoids, flavonoids and phenolic acids. Phamacological investigations revealed that the certain extracts of some Laggera species possess significant bioactivities on anti-inflammation, anti-tumor and anti-viral infection. This review afforded the comprehensive description of the active components as to provide useful references to elucidate their historical clinical application on upper respiratory infection, influenza, parotitis, and recurrent herpes viral infection.
Zhou
Chang-Xin
CX
College of Pharmaceutical Science, Zhejiang University, Hangzhou 310031, China.
Wu
Di-Yao
DY
Li
Xiang-Ping
XP
Wu
Yi-Hang
YH
Zhao
Jun
J
Dong
Nan
N
Yu
Rong-Min
RM
Wei
Wei
W
Zheng
Qun-Xiong
QX
Sun
Han-Dong
HD
Hao
Xiao-Jiang
XJ
Zhao
Yu
Y
D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000494:pharmacology* / Q000627:therapeutic use; D000972:Antineoplastic Agents, Phytogenic / Q000494:pharmacology / Q000627:therapeutic use; D000998:Antiviral Agents / Q000494:pharmacology / Q000627:therapeutic use; D005419:Flavonoids / Q000737:chemistry / Q000302:isolation & purification* / Q000627:therapeutic use; D006801:Humans; D007251:Influenza, Human / Q000188:drug therapy; D015394:Molecular Structure; D010309:Parotitis / Q000188:drug therapy; D008517:Phytotherapy; D010946:Plants, Medicinal / Q000737:chemistry; D029626:Ranunculaceae / Q000737:chemistry; D012141:Respiratory Tract Infections / Q000188:drug therapy*; D012717:Sesquiterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000627:therapeutic use
D000894:Anti-Inflammatory Agents, Non-Steroidal; D000972:Antineoplastic Agents, Phytogenic; D000998:Antiviral Agents; D005419:Flavonoids; D012717:Sesquiterpenes