Protein tyrosine phosphatases as negative regulators of the immune response.
In this mini-review, we provide an overview of those PTPs (protein tyrosine phosphatases) that are relevant to the immune response, highlighting the function of a number of intracellular and transmembrane PTPs that have been identified as having important negative regulatory roles on distinct aspects of host immunity.
Dolton
G M
GM
Department of Medical Biochemistry and Immunology, School of Medicine, Henry Wellcome Research Building, Heath Park, Cardiff CF14 4XX, UK.
Sathish
J G
JG
Matthews
R J
RJ
D003713:Dendritic Cells / Q000276:immunology; D006706:Homeostasis; D006801:Humans; D007107:Immune System / Q000502:physiology; D007113:Immunity, Innate; D008214:Lymphocytes / Q000276:immunology*; D018448:Models, Immunological; D017027:Protein Tyrosine Phosphatases / Q000378:metabolism*; D013601:T-Lymphocytes / Q000276:immunology
D017027:Protein Tyrosine Phosphatases