title: Aldosterone-producing adenoma accompanied with renal artery stenosis.
abstract: We describe a case of secondary hypertension in which aldosterone-producing adenoma (APA) and renal artery stenosis (RAS) coexisted. RAS caused a significant pressure gradient, and successful angioplasty of it improved the affected renal function but did not reduce the systemic blood pressure (SBP). Surgical resection of APA performed several months later reduced SBP. In cases of suspected secondary hypertension, other cause(s) of hypertension should be considered, if hypertension persists after correction of one possible cause.
authors.affiliation: Division of Nephrology, Hypertension and Endocrinology, Department of Medicine, Tohoku University Graduate School of Medicine, Miyagi, Japan. mtanemoto-tky@umin.ac.jp
authors.forename: Masayuki
authors.initials: M
authors.lastname: Tanemoto
authors.forename: Kenji
authors.initials: K
authors.lastname: Honkura
authors.forename: Michiaki
authors.initials: M
authors.lastname: Abe
authors.forename: Fumitoshi
authors.initials: F
authors.lastname: Satoh
authors.forename: Takaaki
authors.initials: T
authors.lastname: Abe
authors.forename: Sadayoshi
authors.initials: S
authors.lastname: Ito
mesh_terms: D000236:Adenoma / Q000150:complications* / Q000378:metabolism; D000310:Adrenal Gland Neoplasms / Q000150:complications* / Q000378:metabolism; D000450:Aldosterone / Q000096:biosynthesis*; D005260:Female; D006801:Humans; D006973:Hypertension / Q000209:etiology*; D008875:Middle Aged; D012078:Renal Artery Obstruction / Q000150:complications*
chemical_list: D000450:Aldosterone