title: Phosphorus-bearing axially chiral biaryls by catalytic asymmetric cross-cyclotrimerization and a first application in asymmetric hydrosilylation.
abstract: A novel and efficient, two-step route to axially chiral biaryls is demonstrated. In a direct asymmetric cross-cyclotrimerization in the presence of a chiral cobalt(I) catalyst, axially chiral biaryls bearing phosphoryl moieties have been prepared, and through indirect evidence the authors have been able to clarify the origin of the stereochemical induction and the nature of the central intermediate in the catalytic cycle. By subsequent reduction of the phosphoryl moiety to the corresponding phosphine, a very efficient and atom-economical approach to chiral systems has been developed. These chiral systems clearly have great potential use as axially chiral monodentate P- or bidentate P,O-ligands, as has been demonstrated by the employment of the novel NAPHEP as a new monodentate acting ligand in an asymmetric hydrosilylation reaction.
authors.affiliation: Leibniz-Institut für Katalyse an der Universität Rostock, Albert-Einstein-Strasse 29 A, 18059 Rostock, Germany. barbara.heller@catalysis.de
authors.forename: Barbara
authors.initials: B
authors.lastname: Heller
authors.forename: Andrey
authors.initials: A
authors.lastname: Gutnov
authors.forename: Christine
authors.initials: C
authors.lastname: Fischer
authors.forename: Hans-Joachim
authors.initials: HJ
authors.lastname: Drexler
authors.forename: Anke
authors.initials: A
authors.lastname: Spannenberg
authors.forename: Dmitry
authors.initials: D
authors.lastname: Redkin
authors.forename: Corinna
authors.initials: C
authors.lastname: Sundermann
authors.forename: Bernd
authors.initials: B
authors.lastname: Sundermann