title: Zoo-FISH in the European mole (Talpa europaea) detects all ancestral Boreo-Eutherian human homologous chromosome associations.
abstract: Zoo-FISH with human whole-chromosome paint probes delineated syntenic association of human homologous chromosome segments 3-21, 14-15, 16-19, 4-8, 7-16 and 12-22 (twice) in the European mole (Talpa europaea, Talpidae, Eulipotyphla, Mammalia). These segment associations represent shared ancestral Boreo-Eutherian traits, half of which were previously not described for Eulipotyphla. The karyotype of the European mole acquired a minimum of 19 translocations and six inversions compared to the presumed Boreo-Eutherian ancestor.
authors.affiliation: Department of Human Genetics, Otto-von-Guericke-University, Magdeburg.
authors.forename: M
authors.initials: M
authors.lastname: Volleth
authors.forename: S
authors.initials: S
authors.lastname: Müller
mesh_terms: D000818:Animals; D005075:Biological Evolution; D002478:Cells, Cultured / Q000648:ultrastructure; D007446:Chromosome Inversion; D020223:Chromosome Painting; D002875:Chromosomes / Q000235:genetics / Q000648:ultrastructure; D002877:Chromosomes, Human / Q000235:genetics; D005260:Female; D005347:Fibroblasts / Q000648:ultrastructure; D006801:Humans; D007621:Karyotyping / Q000662:veterinary; D008322:Mammals / Q000145:classification / Q000235:genetics; D008971:Moles / Q000145:classification / Q000235:genetics*; D017385:Sequence Homology; D012788:Shrews / Q000145:classification / Q000235:genetics; D013045:Species Specificity; D014178:Translocation, Genetic