title: Gold-catalyzed and N-iodosuccinimide-mediated cyclization of gamma-substituted allenamides.
abstract: Chiral gamma-substituted allenamides have been shown to undergo efficient gold-catalyzed and N-iodosuccinimide-mediated cyclization to highly functionalized dihydrofurans. These reactions proceed rapidly and without loss of stereochemistry.
authors.affiliation: Department of Chemistry, Colorado State University, Fort Collins, Colorado 80523, USA.
authors.forename: Christopher J T
authors.initials: CJ
authors.lastname: Hyland
authors.forename: Louis S
authors.initials: LS
authors.lastname: Hegedus
mesh_terms: D000466:Alkadienes / Q000737:chemistry*; D000577:Amides / Q000737:chemistry*; D002384:Catalysis; D003500:Cyclization; D005663:Furans / Q000737:chemistry*; D006046:Gold / Q000737:chemistry*; D015394:Molecular Structure; D013237:Stereoisomerism; D013388:Succinimides / Q000737:chemistry*
chemical_list: D000466:Alkadienes; D000577:Amides; D005663:Furans; D013388:Succinimides; C008155:N-iodosuccinimide; C025947:propadiene; D006046:Gold