title: Hypothalamic hamartoma associated with anterior paraclinoid aneurysm of the internal carotid artery.
abstract: A 15-year-old boy presented with a history of medically refractory gelastic seizures and cognitive impairments. Neuroimaging demonstrated a sessile type hypothalamic hamartoma, which was treated by gamma knife surgery. However, the gelastic seizures only partially decreased and the frequency of seizures remained unchanged. One year later, angiography before surgery detected anterior paraclinoid aneurysm of the left internal carotid artery. Blood pressure and endocrinological examinations showed no abnormality. Direct surgery was performed to treat the aneurysm and hamartoma. No sclerotic changes were noted in the arterial wall. The aneurysm was treated with clipping, and the hamartoma was partially removed. Postoperative course was uneventful and the gelastic seizures disappeared. No evidence for a causal relationship between the hamartoma and aneurysm was found.
authors.affiliation: Department of Neurosurgery, Tokyo Women's Medical University, Tokyo, Japan. kkato@nij.twmu.ac.jp
authors.forename: Koichi
authors.initials: K
authors.lastname: Kato
authors.forename: Fumitaka
authors.initials: F
authors.lastname: Yamane
authors.forename: Motohiro
authors.initials: M
authors.lastname: Hayashi
authors.forename: Hidetoshi
authors.initials: H
authors.lastname: Kasuya
authors.forename: Yoshikazu
authors.initials: Y
authors.lastname: Okada
authors.forename: Osami
authors.initials: O
authors.lastname: Kubo
authors.forename: Hirokazu
authors.initials: H
authors.lastname: Oguni
authors.forename: Makiko
authors.initials: M
authors.lastname: Oosawa
authors.forename: Tomokatsu
authors.initials: T
authors.lastname: Hori
mesh_terms: D000293:Adolescent; D000783:Aneurysm / Q000150:complications* / Q000601:surgery; D002343:Carotid Artery, Internal; D006222:Hamartoma / Q000150:complications* / Q000601:surgery*; D006801:Humans; D007027:Hypothalamic Diseases / Q000150:complications* / Q000601:surgery*; D008297:Male; D016634:Radiosurgery