title: Staged hepatectomy and whipple procedure in metastatic gastroenteropancreatic endocrine carcinoma: report of a case.
abstract: Because of their extremely variable and often indolent natural course, therapeutic management of neuroendocrine tumors is still controversial. Hepatic metastases, especially for gastro-entero-pancreatic-endocrine neoplasms, are common and often responsible for symptomatology onset. Although it has not been clearly shown, liver resection probably represents the best treatment of hepatic metastases, in terms of symptom palliation and survival prolongation. We present a case, to our knowledge the first in the recent literature, of a 60-year-old patient submitted to a pancreatico-duodenectomy for a pancreatic endocrine carcinoma 20 months after a right hepatectomy for an isolated symptomatic metastasis.
authors.affiliation: Dipartimento di Scienze Chirurgiche, Sezione di Clinica Chirurgica Generale e Terapia Chirurgica, Scuola di Specializzazione in Chirurgia Generale, Università Degli Studi di Parma, Parma, Italy. fede53@lycos.com
authors.forename: Federico
authors.initials: F
authors.lastname: Marchesi
authors.forename: Leopoldo
authors.initials: L
authors.lastname: Sarli
authors.forename: Vincenzo
authors.initials: V
authors.lastname: Violi
authors.forename: Luigi
authors.initials: L
authors.lastname: Roncoroni
mesh_terms: D005770:Gastrointestinal Neoplasms / Q000473:pathology*; D006498:Hepatectomy / Q000379:methods*; D006801:Humans; D008113:Liver Neoplasms / Q000556:secondary*; D008297:Male; D008875:Middle Aged; D018358:Neuroendocrine Tumors / Q000556:secondary* / Q000601:surgery*; D010190:Pancreatic Neoplasms / Q000473:pathology*