title: Acute effects of 60-Hz electromagnetic fields on ex vivo murine lymphocyte and macrophage functions, and in vitro tumor cell growth.
abstract: Electromagnetic fields (EMFs) have been associated with impairing health. There are data that associate EMFs exposure to incidence of cancer, but there are conflicting results between epidemiological and laboratory studies. Similarly studies on the effect of EMF on the immune system have produced variable results. In the present study, we evaluated the acute effects of 60 Hz EMFs exposure at 1.0 mT, on proliferation of murine thymic lymphocytes, production of nitric oxide and phagocytosis of Candida albicans by peritoneal murine macrophages, as well as the effect of 8 h/day of EMF exposure during 6 days on proliferation of murine lymphoma L5178Y-R cell growth. We observed that exposure to EMF did not alter lymphocyte and macrophage functions, and did not affect in vitro cell growth of the murine lymphoma cell line L5178Y-R.
authors.affiliation: Departamento de Ciencias Exactas y Apoyo, Universidad Autónoma de Nuevo León, San Nicolás de los Garza, N L México.
authors.forename: J S
authors.initials: JS
authors.lastname: Jacobi-Elizondo
authors.forename: R
authors.initials: R
authors.lastname: Gómez-Flores
authors.forename: R
authors.initials: R
authors.lastname: Tamez-Guerra
authors.forename: C
authors.initials: C
authors.lastname: Rodríguez-Padilla
authors.forename: J A
authors.initials: JA
authors.lastname: Heredia-Rojas
mesh_terms: D000818:Animals; D002176:Candida albicans; D002455:Cell Division; D045744:Cell Line, Tumor / Q000166:cytology; D003208:Concanavalin A / Q000494:pharmacology; D004574:Electromagnetic Fields; D007940:Leukemia L5178 / Q000473:pathology*; D008213:Lymphocyte Activation / Q000187:drug effects; D008262:Macrophage Activation; D017737:Macrophages, Peritoneal / Q000502:physiology; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D009569:Nitric Oxide / Q000096:biosynthesis; D010587:Phagocytosis; D013047:Specific Pathogen-Free Organisms; D013601:T-Lymphocytes / Q000166:cytology / Q000187:drug effects / Q000276:immunology
chemical_list: D003208:Concanavalin A; D009569:Nitric Oxide