[DNA-technologies application for early detection of caries predisposition].
In the paper the possible use of modern DNA-technologies for estimation of gene pool, dental hard tissue resistance to caries prognosis, hereditary predisposition to the main oral diseases diagnosis are presented. Application potentialities of DNA-markers for multiple testing in population are identified. Today very little information is available concerning Russia gene pool characteristics in genome polymorphism, DNA-markers-allelic gene variants, related to the caries predisposition. These characteristics are needed to solve the problems concerning dental diseases prophylaxis and treatment.
Gorbunova
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D000293:Adolescent; D000328:Adult; D004247:DNA / Q000032:analysis*; D003731:Dental Caries / Q000175:diagnosis* / Q000235:genetics; D003937:Diagnosis, Differential; D005260:Female; D020022:Genetic Predisposition to Disease; D006801:Humans; D008297:Male; D008875:Middle Aged; D021141:Nucleic Acid Amplification Techniques / Q000379:methods*; D013997:Time Factors
D004247:DNA