title: [Determination of total organic acids and salicylic acid in extract of Radix isatidis].
abstract: OBJECTIVE
  To develop a quantitative method for determination of the total organic acids and salicyclic acid in the extract of Radix Isatidis.
  
  
  METHODS
  The total organic acids were determined by acid-base titration and the salicylic acid was determined by HPLC.
  
  
  RESULTS
  It was shown that contents of total organic acids and salicylic acid in the extract of Radix Isatidis were 13.0% and 0.22%, respectively.
  
  
  CONCLUSIONS
  The method can control the quality of this extract effectively and accurately.
authors.affiliation: 302 Hospital of PLA and PLA Institute of Chinese Materia Medica, Beijing 100039, China.
authors.forename: Li
authors.initials: L
authors.lastname: Ma
authors.forename: Jian-yuan
authors.initials: JY
authors.lastname: Tang
authors.forename: Zu-lun
authors.initials: ZL
authors.lastname: Lu
authors.forename: Qing-wen
authors.initials: QW
authors.lastname: Liao
authors.forename: Xiao-he
authors.initials: XH
authors.lastname: Xiao
authors.forename: Xiang-jun
authors.initials: XJ
authors.lastname: Zhao
authors.forename: Cheng
authors.initials: C
authors.lastname: Jin
mesh_terms: D002264:Carboxylic Acids / Q000032:analysis*; D002851:Chromatography, High Pressure Liquid / Q000379:methods; D004365:Drugs, Chinese Herbal / Q000737:chemistry* / Q000302:isolation & purification; D031219:Isatis / Q000737:chemistry*; D018517:Plant Roots / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D011786:Quality Control; D020156:Salicylic Acid / Q000032:analysis*; D013678:Technology, Pharmaceutical
chemical_list: D002264:Carboxylic Acids; D004365:Drugs, Chinese Herbal; D020156:Salicylic Acid