Human beta-defensin-3: a promising antimicrobial peptide.
The field of naturally occurring antimicrobial peptides is a research area rapidly expanding due to the high potential of such molecules as new antimicrobial drugs. In this regard, the human beta-defensin-3 is particularly attractive because of its strong antibacterial activity, relative salt-insensitiveness and low toxicity for host cells.
Batoni
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Dipartimento di Patologia sperimentale, Biotecnologie mediche, Infettivologia ed Epidemiologia, Via S. Zeno 35-39, University of Pisa, 56127 Pisa, Italy. batoni@biomed.unipi.it
Maisetta
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G
Esin
S
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Campa
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M
D000595:Amino Acid Sequence; D001419:Bacteria / Q000187:drug effects*; D005658:Fungi / Q000187:drug effects*; D005786:Gene Expression Regulation; D006801:Humans; D008826:Microbial Sensitivity Tests; D008969:Molecular Sequence Data; D017433:Protein Structure, Secondary; D012333:RNA, Messenger / Q000235:genetics; D023083:beta-Defensins / Q000737:chemistry* / Q000235:genetics / Q000494:pharmacology*
C422950:DEFB103A protein, human; D012333:RNA, Messenger; D023083:beta-Defensins