Enzymatic amplification in a bioinspired, autonomous signal cascade.
A two-step reaction cascade is applied to the sequence-specific detection of DNA by enzymatic amplification of the molecular into an optical signal.
Graf
Nora
N
Anorganisch-Chemisches Institut, Ruprecht-Karls-Universität Heidelberg, Heidelberg, Germany.
Krämer
Roland
R
D002256:Carbonic Anhydrases / Q000494:pharmacology*; D004247:DNA / Q000235:genetics / Q000378:metabolism*; D019793:Fluorescein / Q000378:metabolism*; D008027:Light; D015398:Signal Transduction; D015032:Zinc / Q000378:metabolism*
D004247:DNA; D002256:Carbonic Anhydrases; D015032:Zinc; D019793:Fluorescein