title: Scintigraphic gallbladder visualization with gangrenous acalculous cholecystitis.
abstract: Hepatobiliary scintigraphy evaluates the biliary clearance of Tc-99m-labeled iminodiacetic acid agents (Tc-99m IDA) and has a high sensitivity and specificity for the diagnosis of acute cholecystitis. False-negative studies are extremely rare. We describe an apparently normal nonmorphine-augmented hepatobiliary study in gangrenous acalculous cholecystitis. Based on clinical findings, computed tomography, and ultrasound demonstration of a dilated gallbladder, a cholecystectomy was performed. Pathologic examination of the gallbladder revealed acute gangrenous cholecystitis with culture positive for Klebsiella pneumoniae.
authors.affiliation: Nuclear Medicine, Department of Radiology, Hospital of Saint Raphael, Yale University School of Medicine, New Haven, CT 06511, USA. clananian@yahoo.com
authors.forename: Christopher
authors.initials: C
authors.lastname: Ananian
authors.forename: Andrew
authors.initials: A
authors.lastname: Dunn
authors.forename: Vazrik
authors.initials: V
authors.lastname: Mansourian
authors.forename: Vicente J
authors.initials: VJ
authors.lastname: Caride
mesh_terms: D042101:Acalculous Cholecystitis / Q000000981:diagnostic imaging* / Q000601:surgery; D000368:Aged; D005188:False Negative Reactions; D005260:Female; D005704:Gallbladder / Q000000981:diagnostic imaging* / Q000473:pathology* / Q000601:surgery; D005734:Gangrene / Q000000981:diagnostic imaging / Q000601:surgery; D006801:Humans; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals; D019785:Technetium Tc 99m Disofenin
chemical_list: D019275:Radiopharmaceuticals; D019785:Technetium Tc 99m Disofenin