title: [Affection of Bushen Shengjing pill on NO and NOS in testicle and ante-oxidization of rat with spermatogenic cell injury].
abstract: OBJECTIVE
  Discuss the functional mechanism of treating male infertility with Bushen Shengjing pill (BS).
  
  
  METHODS
  Fill the SD rat with adenine so as to injure the germ cell which will produce the model rat with kidney yang deficiency. Measure the activity of SOD and NOS, the amount of NO and MDA in the testicle.
  
  
  RESULTS
  BS can promote the activity of SOD, reduce the activity of NOS and the amount of NO and MDA.
  
  
  CONCLUSIONS
  BS has the function of protecting the germ cell which is closely related to the function that the pill can promote the activity of SOD, reduce the activity of NOS and the amount of NO and MDA.
authors.affiliation: Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100700, China. amwds@163.com
authors.forename: A-min
authors.initials: AM
authors.lastname: Yang
authors.forename: Yue-qing
authors.initials: YQ
authors.lastname: Li
authors.forename: Hai-song
authors.initials: HS
authors.lastname: Li
authors.forename: Chong-shun
authors.initials: CS
authors.lastname: Song
authors.forename: Ying
authors.initials: Y
authors.lastname: Ren
authors.forename: Jun-xiang
authors.initials: JX
authors.lastname: Yin
mesh_terms: D000225:Adenine; D000818:Animals; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification / Q000494:pharmacology*; D005303:Fertility Agents, Male / Q000494:pharmacology; D007674:Kidney Diseases / Q000139:chemically induced / Q000378:metabolism*; D008297:Male; D008315:Malondialdehyde / Q000378:metabolism; D009569:Nitric Oxide / Q000378:metabolism*; D019001:Nitric Oxide Synthase / Q000378:metabolism*; D010946:Plants, Medicinal / Q000737:chemistry; D011897:Random Allocation; D051381:Rats; D017207:Rats, Sprague-Dawley; D013091:Spermatogenesis / Q000187:drug effects; D013482:Superoxide Dismutase / Q000378:metabolism; D013737:Testis / Q000378:metabolism; D016711:Yang Deficiency / Q000139:chemically induced / Q000378:metabolism*
chemical_list: D004338:Drug Combinations; D004365:Drugs, Chinese Herbal; D005303:Fertility Agents, Male; D009569:Nitric Oxide; D008315:Malondialdehyde; D019001:Nitric Oxide Synthase; D013482:Superoxide Dismutase; D000225:Adenine