title: Reproductive outcome of septate uterus after hysteroscopic treatment with neodymium:YAG laser.
abstract: OBJECTIVE
  The aim of this study was to assess fertility outcome and obstetrical prognosis of 46 patients after hysteroscopic section of uterine septa with neodysmium:yttrium-aluminum-garnet (Nd:YAG) laser.
  
  
  BACKGROUND
  Approximately 15-25% of spontaneous miscarriages are related to Müllerian fusion defects, most of which are associated with uterine septa. Operative hysteroscopy is a safe and effective treatment for uterine septa.
  
  
  METHODS
  Forty-six sterile patients with septate uterus received hysteroscopic metroplasty with Nd:YAG laser. Forty-one patients with incomplete septate uterus were under the guidance of B-ultrasonography, while the other 5 patients with complete septate uterus were treated by laparoscopy.
  
  
  RESULTS
  The metroplasty was successfully conducted in 45 patients, with a success rate of 98% (45 /46). Postoperative follow-up examinations of 28 patients revealed pregnancy within 12 months in 20 patients, 16 of whom acquired term delivery. The pregnancy rate within 1 year was 71%.
  
  
  CONCLUSIONS
  Hysteroscopic treatment of septate uterus with Nd:YAG laser is effective. The cervix may not be excessively dilated, the intraoperative bleeding can be thoroughly controlled, and the procedure under local anesthesia is relatively safe.
authors.affiliation: Reproductive Medical Center, Renmin Hospital of Wuhan University, Wuhan, PR of China. DrYangQing@hotmail.com
authors.forename: Jing
authors.initials: J
authors.lastname: Yang
authors.forename: Tai-Lang
authors.initials: TL
authors.lastname: Yin
authors.forename: Tai-Ung
authors.initials: TU
authors.lastname: Yin
authors.forename: Wang-Ming
authors.initials: WM
authors.lastname: Xu
authors.forename: Liang-Bin
authors.initials: LB
authors.lastname: Xia
authors.forename: Lian-Gbin
authors.initials: LG
authors.lastname: Xia
authors.forename: Ai-Bin
authors.initials: AB
authors.lastname: Li
authors.forename: Jing
authors.initials: J
authors.lastname: Hu
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D015907:Hysteroscopy; D053685:Laser Therapy; D011247:Pregnancy; D018873:Pregnancy Rate; D012189:Retrospective Studies; D014463:Ultrasonography; D014599:Uterus / Q000002:abnormalities* / Q000000981:diagnostic imaging / Q000601:surgery*