title: The effect of an alternative medical procedure upon low-frequency oscillations in cutaneous blood flow velocity.
abstract: OBJECTIVE
  Compression of the fourth ventricle (CV-4) is a manual, noninvasive procedure that reportedly affects the cranial rhythmic impulse, a phenomenon recognized by practitioners of cranial manipulation, that is concomitant with low-frequency Traube-Hering (TH) oscillations in blood flow velocity. This study examines the CV-4 and its effect upon blood flow velocity.
  
  
  METHODS
  Human subjects were paired with 28 individual physicians for application of the CV-4, and the duration of the application was recorded. Flowmetry records tracking the course of the procedure were obtained, 20 of which were useable for intergroup comparisons. Segments of these records (control, treatment, response) were Fourier-transformed; the Fourier-transformed spectra were subtracted from one another and the resultant difference-spectra compared.
  
  
  RESULTS
  The mean CV-4 procedure length was 4.43 +/- 2.22 minutes. The mean frequency of the TH waveform visible in the blood flowmetry record was 7.10 +/- 2.07 cpm. The CV-4 procedure specifically affected the low-frequency oscillations in blood flow velocity. After application, the amplitude of the TH, 0.10 Hz, frequency wave increased (relative area units: control minus treatment [0.08010 units) compared with control minus response [-0.03358 units]; P = .011).
  
  
  CONCLUSIONS
  This study showed that CV-4 has an effect on the TH frequency component of blood flow velocity. The practitioners of cranial manipulation who participated in this study affected their subjects in a quantifiable manner with the application of the CV-4 procedure.
authors.affiliation: Department of Osteopathic Manipulative Medicine, Midwestern University, Downers Grove, Ill 60515, USA.
authors.forename: Kenneth E
authors.initials: KE
authors.lastname: Nelson
authors.forename: Nicette
authors.initials: N
authors.lastname: Sergueef
authors.forename: Thomas
authors.initials: T
authors.lastname: Glonek
mesh_terms: D000328:Adult; D000368:Aged; D000704:Analysis of Variance; D001783:Blood Flow Velocity; D005260:Female; D005583:Fourier Analysis; D020546:Fourth Ventricle; D006801:Humans; D017078:Laser-Doppler Flowmetry; D008297:Male; D026301:Manipulation, Osteopathic; D008875:Middle Aged; D009991:Oscillometry; D011312:Pressure; D015203:Reproducibility of Results; D012867:Skin / Q000098:blood supply*; D012886:Skull; D013997:Time Factors