title: CSF tau protein: a new prognostic marker for Guillain-Barré syndrome.
abstract: We measured the CSF tau protein levels in 26 patients with Guillain-Barré syndrome. The levels of the poor outcome group (Hughes grade at 6 months was between II and VI, n = 6) were higher than those of the good outcome group (0 or I, n = 20) (p < 0.0005). The higher levels of CSF tau may reflect axonal degeneration and could predict a poor clinical outcome in Guillain-Barré syndrome.
authors.affiliation: Department of Neurology, Kohnan Hospital, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Jin
authors.forename: A
authors.initials: A
authors.lastname: Takeda
authors.forename: Y
authors.initials: Y
authors.lastname: Shiga
authors.forename: S
authors.initials: S
authors.lastname: Sato
authors.forename: A
authors.initials: A
authors.lastname: Ohnuma
authors.forename: H
authors.initials: H
authors.lastname: Nomura
authors.forename: H
authors.initials: H
authors.lastname: Arai
authors.forename: S
authors.initials: S
authors.lastname: Kusunoki
authors.forename: M
authors.initials: M
authors.lastname: Ikeda
authors.forename: Y
authors.initials: Y
authors.lastname: Itoyama
mesh_terms: D000328:Adult; D000368:Aged; D000906:Antibodies / Q000097:blood; D001369:Axons; D015415:Biomarkers / Q000134:cerebrospinal fluid; D004568:Electrodiagnosis; D005260:Female; D006017:Glycolipids / Q000276:immunology; D020275:Guillain-Barre Syndrome / Q000134:cerebrospinal fluid* / Q000150:complications / Q000175:diagnosis / Q000503:physiopathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009410:Nerve Degeneration / Q000209:etiology / Q000503:physiopathology; D017063:Outcome Assessment, Health Care; D011379:Prognosis; D012121:Respiration, Artificial; D016875:tau Proteins / Q000134:cerebrospinal fluid*
chemical_list: D000906:Antibodies; D015415:Biomarkers; D006017:Glycolipids; D016875:tau Proteins