Point: Interleukin-6 does have a beneficial role in insulin sensitivity and glucose homeostasis.
Pedersen
Bente K
BK
The Centre of Inflammation and Metabolism, Department of Infectious Diseases, Rigshospitalet, The Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark. bkp@rh.dk
Febbraio
Mark A
MA
D055372:AMP-Activated Protein Kinases; D000818:Animals; D003924:Diabetes Mellitus, Type 2 / Q000378:metabolism / Q000503:physiopathology; D015444:Exercise / Q000502:physiology; D005227:Fatty Acids / Q000378:metabolism; D005947:Glucose / Q000378:metabolism*; D006706:Homeostasis / Q000502:physiology*; D006801:Humans; D007328:Insulin / Q000378:metabolism; D007333:Insulin Resistance / Q000502:physiology*; D015850:Interleukin-6 / Q000502:physiology*; D050356:Lipid Metabolism / Q000502:physiology; D051379:Mice; D009097:Multienzyme Complexes / Q000502:physiology; D010084:Oxidation-Reduction; D017346:Protein Serine-Threonine Kinases / Q000502:physiology; D000071223:Suppressor of Cytokine Signaling 3 Protein; D050826:Suppressor of Cytokine Signaling Proteins / Q000378:metabolism; D014409:Tumor Necrosis Factor-alpha / Q000378:metabolism
D005227:Fatty Acids; D007328:Insulin; D015850:Interleukin-6; D009097:Multienzyme Complexes; C106644:SOCS3 protein, human; D000071223:Suppressor of Cytokine Signaling 3 Protein; D050826:Suppressor of Cytokine Signaling Proteins; D014409:Tumor Necrosis Factor-alpha; D017346:Protein Serine-Threonine Kinases; D055372:AMP-Activated Protein Kinases; D005947:Glucose