title: Tribological monitoring of drugs used for the treatment of arthropathies.
abstract: Lubricating capacity of drugs injected into articular cavity were tested using a pendulum tribometer. The findings indicate that friction coefficient for a pair simulating metallopolymeric articular endoprosthesis is changed under the effect of electromagnetic field after lubrication. Regularities of these changes depend on the nature and mechanism of action of drugs. A method for rapid evaluation of the lubricating characteristics of drugs is proposed for optimizing their therapeutic effect on joints.
authors.affiliation: Hermetology Department, V. A. Belyi Institute of Mechanics of Metallopolymeric Systems, National Academy of Sciences, Belarus, Gomel.
authors.forename: L S
authors.initials: LS
authors.lastname: Pinchuk
authors.forename: Yu M
authors.initials: YM
authors.lastname: Chernyakova
authors.forename: Z V
authors.initials: ZV
authors.lastname: Kadolich
authors.forename: V I
authors.initials: VI
authors.lastname: Nikolaev
mesh_terms: D016903:Drug Monitoring / Q000379:methods*; D006801:Humans; D007592:Joint Diseases / Q000188:drug therapy*