title: Sarcoid granuloma on black tattoo.
abstract: We report the case of a patient with a black and turquoise tattoo who developed sarcoid granulomas on the areas of black pigment. Patch tests showed a positive reaction to nickel, cobalt, and cadmium; spectrophotometric analysis of the black pigment revealed the presence of nickel and cobalt among other metals. Although the pathogenesis of sarcoid granulomas is unknown, it seems that a delayed type hypersensitivity reaction is one of the mechanisms involved.
authors.affiliation: Department of Dermatology, Clinical Hospital of Valladolid.
authors.forename: Ana María
authors.initials: AM
authors.lastname: Morales-Callaghan
authors.forename: Miguel
authors.initials: M
authors.lastname: Aguilar-Bernier
authors.forename: Gerardo
authors.initials: G
authors.lastname: Martínez-García
authors.forename: Alberto
authors.initials: A
authors.lastname: Miranda-Romero
mesh_terms: D000328:Adult; D003035:Cobalt / Q000009:adverse effects; D004342:Drug Hypersensitivity; D005260:Female; D006099:Granuloma / Q000139:chemically induced* / Q000276:immunology; D006801:Humans; D006968:Hypersensitivity, Delayed / Q000139:chemically induced*; D009532:Nickel / Q000009:adverse effects; D010858:Pigmentation; D013653:Tattooing / Q000009:adverse effects*
chemical_list: D003035:Cobalt; D009532:Nickel