Persistence of Cloquet's canal in normal healthy eyes.
OBJECTIVE
Optic nerve head (ONH) structural imaging with state-of-the-art, high-speed, ultra-high-resolution optical coherence tomography (hsUHR-OCT).


METHODS
Observational cohort study.


METHODS
ONH centered 3-dimensional (94,371,840 voxel measurements in a 6- x 6- x 1.4-mm tissue volume) hsUHR-OCT data were obtained in one eye from each of six males and nine females normal healthy volunteers (40 +/- 9 years of age). The presence of structures projecting anteriorly from the disk into the vitreous was noted.


RESULTS
Structures were noted in 14 of 15 (93%) examined eyes, emanating from the rim of the ONH at the nasal inferior sector, presenting as thin tissue meandering into the vitreous.


CONCLUSIONS
Previous technologies provided limited visualization of ONH structures. The ability to scan the entire disk using 3-dimensional OCT (3D-OCT) in a high-density raster pattern reveals a high frequency of persistence of Cloquet's canal in the normal healthy eye.
Kagemann
Larry
L
UPMC Eye Center, Eye and Ear Institute, Department of Ophthalmology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA.
Wollstein
Gadi
G
Ishikawa
Hiroshi
H
Gabriele
Michelle L
ML
Srinivasan
Vivek J
VJ
Wojtkowski
Maciej
M
Duker
Jay S
JS
Fujimoto
James G
JG
Schuman
Joel S
JS
D000328:Adult; D004628:Embryonic Structures / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D021621:Imaging, Three-Dimensional / Q000379:methods; D008297:Male; D009898:Optic Disk / Q000000981:diagnostic imaging*; D041623:Tomography, Optical Coherence; D014463:Ultrasonography; D014822:Vitreous Body / Q000000981:diagnostic imaging