title: Two cases of asthma in handicapped elderly persons in which assisted inhalation therapy was effective.
abstract: BACKGROUND
  Chronic airway inflammation is a basic pathology of bronchial asthma and it is important to control the inflammation by anti-inflammatory therapy mainly with steroids. However, in asthma in the elderly, there are cases where physicians hesitate to introduce the inhaled corticosteroid (ICS) therapy based on the diagnosis that the use of inhalants is difficult due to the existence of a functional lesion accompanying asthma.
  
  
  RESULTS
  In cases where self-administrated inhalation therapy is difficult to execute due to the accompaniment of a functional lesion and in cases where sufficient curative effects of steroids are not produced in self-inhalation, administration of assisted inhalation resulted in improvement of clinical symptoms and pulmonary function and was proven effective.
  
  
  CONCLUSIONS
  Assisted inhalation therapy is expected to be useful in general and also in terms of expanding the application of ICS in the asthma in the elderly.
authors.affiliation: Third Department of Internal Medicine, Wakayama Medical University, School of Medicine, Wakayama, Japan.
authors.forename: Kazuto
authors.initials: K
authors.lastname: Matsunaga
authors.forename: Satoru
authors.initials: S
authors.lastname: Yanagisawa
authors.forename: Tomohiro
authors.initials: T
authors.lastname: Ichikawa
authors.forename: Kazuhito
authors.initials: K
authors.lastname: Ueshima
authors.forename: Keiichirou
authors.initials: K
authors.lastname: Akamatsu
authors.forename: Tsunahiko
authors.initials: T
authors.lastname: Hirano
authors.forename: Masanori
authors.initials: M
authors.lastname: Nakanishi
authors.forename: Toshiyuki
authors.initials: T
authors.lastname: Yamagata
authors.forename: Yoshiaki
authors.initials: Y
authors.lastname: Minakata
authors.forename: Masakazu
authors.initials: M
authors.lastname: Ichinose
mesh_terms: D000280:Administration, Inhalation; D000369:Aged, 80 and over; D000730:Androstadienes / Q000494:pharmacology*; D018926:Anti-Allergic Agents / Q000494:pharmacology*; D001249:Asthma / Q000188:drug therapy*; D006233:Persons with Disabilities; D005260:Female; D000068298:Fluticasone; D006801:Humans; D012138:Respiratory Therapy
chemical_list: D000730:Androstadienes; D018926:Anti-Allergic Agents; D000068298:Fluticasone