Solid-pseudopapillary tumor of the pancreas.
BACKGROUND
Solid-pseudopapillary tumor (SPT) of the pancreas is a low-grade malignancy, which has been infrequently observed in adolescent and young adult females since first report by Frantz in 1959. In this article, we describe our experience of 8 cases of SPT with the clinical features, diagnosis, treatments, and outcomes.


METHODS
We retrospectively reviewed the medical records and images of 8 patients who underwent surgery for SPT between January 1995 and December 2004.


RESULTS
Seven females and 1 male with the mean age of 29 years (range, 10 to 64) at presentation were identified. Three patients presented palpable abdominal mass, 2 with abdominal pain, and the remainder with no specific symptom. The mean diameter of the tumors was 7.9 cm (range, 4.0 to 10.0). Four were located in the tail, 3 in the body, and 1 in the head. Surgical procedure included distal pancreatectomy with/without splenectomy in 7 patients and Whipple operation in 1 with no surgical morbidity and mortality. All were alive without evidence of recurrence after mean follow-up of 26.4 months (range, 1 to 66).


CONCLUSIONS
SPT of the pancreas is an unusual neoplasm and typically occurs in young females presenting well-demarcated pancreatic masses, which are amenable to cure by complete surgical resection.
Seo
Hyang-Eun
HE
Department of Internal Medicine, School of Medicine, Kyungpook National University, Daegu, South Korea.
Lee
Myung-Kwon
MK
Lee
Young-Doo
YD
Jeon
Seong-Woo
SW
Cho
Chang-Min
CM
Tak
Won-Young
WY
Kweon
Young-Oh
YO
Kim
Sung-Kook
SK
Choi
Yong-Hwan
YH
Bae
Han-Ik
HI
Kim
Sang-Geol
SG
Yoon
Young-Kook
YK
D000293:Adolescent; D000328:Adult; D014408:Biomarkers, Tumor / Q000097:blood; D002291:Carcinoma, Papillary / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D002648:Child; D003082:Colectomy; D003951:Diagnostic Errors; D016099:Endoscopy, Gastrointestinal; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007723:Korea; D007889:Leiomyoma / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D007890:Leiomyosarcoma / Q000175:diagnosis; D008297:Male; D008499:Medical Records; D008875:Middle Aged; D010180:Pancreatectomy; D010190:Pancreatic Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D010534:Peritoneal Neoplasms / Q000175:diagnosis; D012189:Retrospective Studies; D013156:Splenectomy; D013274:Stomach Neoplasms / Q000175:diagnosis; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D018084:Ultrasonography, Interventional
D014408:Biomarkers, Tumor