Neuroblastoma presenting with dilated cardiomyopathy.
We report an infant with neuroblastoma who presented with dilated cardiomyopathy. A 3-month-old girl presented with dilated cardiomyopathy diagnosed as stage III neuroblastoma. Since total resection was impossible, chemotherapy was started. Cardiomyopathy was normalized by improvement of neuroblastoma. The prompt improvement of cardiac function following treatment of neuroblastoma suggested that cardiomyopathy in this patient was caused by the increase in catecholamines secreted by neuroblastoma and that reduction in catecholamines by treatment of neuroblastoma led to improvement in the cardiomyopathy.
Kato
M
M
Division of Hematology/Oncology, Saitama Children's Medical Center, Saitama, Japan.
Hirata
S
S
Kikuchi
A
A
Ogawa
K
K
Kishimoto
H
H
Hanada
R
R
D002311:Cardiomyopathy, Dilated / Q000188:drug therapy / Q000209:etiology* / Q000378:metabolism; D002395:Catecholamines / Q000378:metabolism; D005260:Female; D006801:Humans; D007223:Infant; D009447:Neuroblastoma / Q000150:complications* / Q000188:drug therapy / Q000378:metabolism
D002395:Catecholamines