title: O-arylative Passerini reactions.
abstract: The three-component addition of isocyanides to phenol derivatives and aldehydes proceeds easily in methanol to form O-arylated compounds in a new Passerini-type reaction. The key step of the conversion lies in an irreversible Smiles rearrangement of intermediate phenoxyimidate adducts. It represents the first use of a Smiles rearrangement in a Passerini reaction. [reaction: see text]
authors.affiliation: Laboratoire Chimie et procédés, Ecole Nationale Supérieure de Techniques Avancées, 32 Boulevard Victor, 75739 Paris Cedex 15, France. laurent.elkaim@ensta.fr
authors.forename: Laurent
authors.initials: L
authors.lastname: El Kaim
authors.forename: Marie
authors.initials: M
authors.lastname: Gizolme
authors.forename: Laurence
authors.initials: L
authors.lastname: Grimaud