title: Gastric bypass for morbidly obese patients with established cardiac disease.
abstract: BACKGROUND
  Bariatric surgery has often been avoided in patients with known cardiac disease because of the risks inherent in this patient population. This study was done to evaluate both the risks and benefits of Roux-en-Y gastric bypass (RYGBP) in morbidly obese patients with established cardiac disease.
  
  
  METHODS
  Data were analyzed to compare preoperative with postoperative co-morbid cardiac risk factors, peri-operative and postoperative complications, and change in body mass index (BMI) in 77 consecutive patients who had a preoperative diagnosis of cardiac disease and underwent RYGBP between March 1998 and January 31, 2006. Findings were compared to a concomitant control group without cardiac disease.
  
  
  RESULTS
  The preoperative presence of cardiac disease was manifested primarily as coronary artery disease (CAD) (45 patients) or as congestive heart failure (CHF) (32 patients). Of the patients with CAD, 60% had diabetes, 91% had hypertension and 39% had hyperlipidemia. 58% had one or more prior invasive cardiac procedures. In the CHF group, 50% had diabetes, 71% had hypertension and 44% had hyperlipidemia. The average length of stay was 3.7 days for CAD patients and 3.3 days for CHF compared to 3.0 days for controls. All co-morbid conditions were improved, and no patient died from cardiac disease. However, one patient died as a complication of GI bleeding, one patient subsequently underwent revascularization and another underwent stenting. Other complications up to 5 years postoperatively were frequent but seldom life-threatening.
  
  
  CONCLUSIONS
  RYGBP surgery in patients with existing cardiac disease appears to have acceptable risk and is effective in reducing the co-morbid conditions of diabetes, hypertension, hyperlipidemia, sleep apnea and arthritis, but longer term data are needed.
authors.affiliation: The Center for Surgical Weight Loss, Department of Surgery, University of Cincinnati College of Medicine, Cincinnati, OH 45219, USA.
authors.forename: Grady D
authors.initials: GD
authors.lastname: Alsabrook
authors.forename: Hope R
authors.initials: HR
authors.lastname: Goodman
authors.forename: J Wesley
authors.initials: JW
authors.lastname: Alexander
mesh_terms: D015897:Comorbidity; D003327:Coronary Disease / Q000453:epidemiology*; D003925:Diabetic Angiopathies / Q000453:epidemiology; D005260:Female; D015390:Gastric Bypass; D006333:Heart Failure / Q000453:epidemiology*; D006801:Humans; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D009767:Obesity, Morbid / Q000453:epidemiology* / Q000601:surgery; D018570:Risk Assessment; D012307:Risk Factors