title: A new method for measuring misclassification of maternal sets in maternally linked birth records: true and false linkage proportions.
abstract: OBJECTIVE
  Numerous studies have used maternally linked birth records to investigate perinatal outcomes, maternal behaviors, and the quality of vital records birth data. Little attention has been given to assessing errors in the linkages and to understanding how such errors affect estimates derived from the linked data. The author developed a framework for conceptualizing maternal linkage error and measures for quantifying it, and examined the behavior of the new measures in a maternally linked file.
  
  
  METHODS
  Linkage errors were conceptualized as misclassification, with the classes being the maternal sets (records classified as representing different births to the same woman). The true linkage proportion, analogous to sensitivity, was used to capture the degree to which all of a woman's births were assigned to a single maternal set; the false linkage proportion, analogous to specificity, was used to capture the degree to which the assigned maternal sets combined births from different women. The behavior of the two proportions was examined by introducing increasing degrees of linkage error into a maternally linked file.
  
  
  RESULTS
  Both measures indicated greater misclassification with increasing simulated linkage errors.
  
  
  CONCLUSIONS
  The new measures may be a useful tool for assessing the quality of maternally linked data, as well as other types of linked records where the linkages are within a single file. This is a necessary step towards developing methods for addressing misclassification bias in studies of maternally linked records through sensitivity analysis, adjustment, and other means.
authors.affiliation: Center for Health Research, Constella Group, LLC, 2605 Meridian Parkway, Suite 200, Durham, NC 27713, USA. jleiss@constellagroup.com
authors.forename: Jack K
authors.initials: JK
authors.lastname: Leiss
mesh_terms: D015982:Bias; D001719:Birth Certificates; D005220:Fathers / Q000145:classification; D005260:Female; D006801:Humans; D007229:Infant Welfare / Q000145:classification*; D007231:Infant, Newborn; D008498:Medical Record Linkage / Q000379:methods* / Q000592:standards; D009035:Mothers / Q000145:classification*; D009275:Names; D009657:North Carolina / Q000453:epidemiology; D010355:Patient Identification Systems / Q000145:classification; D011247:Pregnancy; D011256:Pregnancy Outcome / Q000453:epidemiology*; D040442:Public Health Informatics / Q000592:standards; D012107:Research Design; D012680:Sensitivity and Specificity