title: Dalhousie dyspnea scales: Pictorial scales to measure dyspnea during induced bronchoconstriction.
abstract: The aim of this study was to validate our Dalhousie Dyspnea Scales in children referred for histamine bronchoprovocation challenge. Seventy-four children rated their dyspnea after each FEV(1) measurement following inhalation of doubling histamine concentrations from 0.125 to 8.0 mg/ml by the standard tidal breathing method. Serial FEV(1) and dyspnea rating using the Dalhousie Dyspnea Scales were recorded and Kendall's tau was computed for dyspnea rating versus fall in FEV(1). Subjects were split into those with positive (DeltaFEV(1) >or= 20% with PC(20) <or= 8 mg/ml) or negative histamine challenge test. During histamine inhalation, dyspnea ratings on each of the subscales rose as FEV(1) fell across subjects, whether or not they were histamine-responsive (main effect), and then fell dramatically following relief of induced obstruction by bronchodilator.The Dalhousie Dyspnea Scales are useful and accurate tools to measure dyspnea due to bronchoconstriction in children.
authors.affiliation: Department of Pediatrics, Dalhousie University, Halifax, Nova Scotia, Canada. pianosi.paolo@mayo.edu
authors.forename: Paul
authors.initials: P
authors.lastname: Pianosi
authors.forename: Chloe P
authors.initials: CP
authors.lastname: Smith
authors.forename: Anthony
authors.initials: A
authors.lastname: Almudevar
authors.forename: Patrick J
authors.initials: PJ
authors.lastname: McGrath
mesh_terms: D000280:Administration, Inhalation; D001985:Bronchial Provocation Tests; D016084:Bronchoconstriction / Q000502:physiology*; D002648:Child; D004417:Dyspnea / Q000175:diagnosis* / Q000503:physiopathology; D005260:Female; D005541:Forced Expiratory Volume / Q000502:physiology; D006632:Histamine / Q000008:administration & dosage; D018494:Histamine Agents / Q000008:administration & dosage; D006801:Humans; D008297:Male; D049451:Nomograms; D012720:Severity of Illness Index
chemical_list: D018494:Histamine Agents; D006632:Histamine