Relationships between Mycobacterium isolates from patients with pulmonary mycobacterial infection and potting soils.
High numbers of mycobacteria, including known pathogenic species such as Mycobacterium avium, Mycobacterium intracellulare, and Mycobacterium chelonae, were recovered from aerosols produced by pouring commercial potting soil products and potting soil samples provided by patients with pulmonary mycobacterial infections. The dominant mycobacteria in the soil samples corresponded to the dominant species implicated clinically. Profiles of large restriction fragments obtained by pulsed-field gel electrophoresis demonstrated a closely related pair of M. avium isolates recovered from a patient and from that patient's own potting soil. Thus, potting soils are potential sources of infection by environmental mycobacteria. Use of dust-excluding masks should be considered during potting or other activities that generate aerosol with soil.
De Groote
Mary Ann
MA
Department of Molecular, Cellular, and Developmental Biology, University of Colorado, Boulder, CO 80309, USA.
Pace
Norman R
NR
Fulton
Kayte
K
Falkinham
Joseph O
JO
D000336:Aerosols; D016521:Electrophoresis, Gel, Pulsed-Field; D051639:Gardening; D006801:Humans; D008171:Lung Diseases / Q000382:microbiology*; D015269:Mycobacterium avium Complex / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*; D015270:Mycobacterium avium-intracellulare Infection / Q000382:microbiology*; D012988:Soil Microbiology
D000336:Aerosols