title: [Hereditary mixed polyposis syndrome. First report in Mexico].
abstract: OBJECTIVE
  Report for first time in Mexico a case of hereditary mixed polyposis and review the literature.
  
  
  BACKGROUND
  The hereditary mixed polyposis syndrome (HMPS) is an uncommon condition, distinguished by presence of a different histological pattern of polyps in digestive tract, clinically manifested by diarrhea, anemia and weight loss.
  
  
  METHODS
  Male patient, 38 years old, with familiar antecedent (dead sister) with polyps and gastric cancer. With history of a 1 year with bleeding and mucous diarrhea, and weight loss of a 28.6 pounds. Pale at physical examination, without abdominal signs. At blood test with hemoglobin of 9.7 g/dL, and colonoscopy with multiple polyps within colon and rectum, upper endoscopy with a big esophageal polyp and multiple polyps in gastric and duodenal lining smaller than 1 cm. Contrast study of intestine was normal. Histopathologic study of the polyps report mixed pattern of polyps: (hyperplasic-adenomatous, juvenile-adenomatous, adenoma-inflammatory-hyperplasic, hyperplasic-adenomatous with a high degree dysplasia); juvenile in esophagus, and hyperplasic in stomach and duodenum. Patient was undergone to totalproctocolectomy and reconstruction by "J" ileoanal pouch with good outcome, and endoscopic esophageal polypectomy, with actual surveillance.
authors.affiliation: Servicio de Cirugía de Colon y Recto, Hospital de Especialidades Centro Médico Nacional Siglo XXI. Instituto Mexicano del Seguro Social. rochajlrr@aol.com.mx
authors.forename: José Luis
authors.initials: JL
authors.lastname: Rocha Ramírez
authors.forename: Eduardo
authors.initials: E
authors.lastname: Villanueva Sáenz
authors.forename: Paulino Martínez
authors.initials: PM
authors.lastname: Hernández-Magro
authors.forename: Ernesto
authors.initials: E
authors.lastname: Sierra Montenegro
authors.forename: Rene
authors.initials: R
authors.lastname: Soto Quirino
authors.forename: Javier
authors.initials: J
authors.lastname: Pérez Aguirre
authors.forename: Enrique
authors.initials: E
authors.lastname: Blanco Lemus
mesh_terms: D011125:Adenomatous Polyposis Coli / Q000175:diagnosis*; D000328:Adult; D006801:Humans; D008297:Male; D008800:Mexico