title: Detection of Mycobacterium tuberculosis in sputum from Suruí Indian subjects, Brazilian Amazon.
abstract: This investigation aimed at the detection of Mycobacterium tuberculosis (MTB) in the sputum of Suruí Indian subjects from Amazonia, Brazil. Polymerase chain reaction analyses were positive for 12 samples, five of which were also culture-positive (N = 147). Four MTB genotypes were identified, one of which showed resistance to rifampicin and isoniazid. The study also highlighted one village complex as of particular importance, considering the relatively high number of tuberculosis cases reported and of MTB isolates obtained.
authors.affiliation: Escola Nacional de Saúde Pública Sérgio Arouca, Fiocruz, Rio de Janeiro, RJ, 21041-210, Brasil.
authors.forename: Paulo Cesar
authors.initials: PC
authors.lastname: Basta
authors.forename: Maraníbia A C
authors.initials: MA
authors.lastname: Oelemann
authors.forename: Walter M R
authors.initials: WM
authors.lastname: Oelemann
authors.forename: Leila de Souza
authors.initials: Lde S
authors.lastname: Fonseca
authors.forename: Carlos E A
authors.initials: CE
authors.lastname: Coimbra
mesh_terms: D001938:Brazil / Q000453:epidemiology; D004269:DNA, Bacterial / Q000032:analysis; D005838:Genotype; D006801:Humans; D007199:Indians, South American; D009169:Mycobacterium tuberculosis / Q000187:drug effects / Q000235:genetics / Q000302:isolation & purification*; D016133:Polymerase Chain Reaction; D013183:Sputum / Q000382:microbiology*; D014376:Tuberculosis / Q000175:diagnosis* / Q000453:epidemiology
chemical_list: D004269:DNA, Bacterial