Microbial metabolism of the prenylated chalcone xanthohumol.
Microbial metabolism of xanthohumol (1), a prenylated chalcone isolated from hops, gave three novel glucosylated derivatives (2-4) and a known compound, isoxanthohumol (5). The structures of the new compounds were identified as xanthohumol 4'-O-beta-glucopyranoside (2), xanthohumol 4,4'-O-beta-diglucopyranoside (3), and 5-methoxy-8-prenylnaringenin 7-O-beta-glucopyranoside (4) on the basis of spectroscopic methods.
Kim
Hyun Jung
HJ
College of Pharmacy and Research Institute of Drug Development, Chonnam National University, Gwangju 500-757, Korea.
Lee
Ik-Soo
IS
D002599:Chalcone / Q000378:metabolism*; D005419:Flavonoids; D005658:Fungi / Q000378:metabolism*; D005960:Glucosides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D027582:Humulus / Q000737:chemistry*; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D011427:Propiophenones / Q000378:metabolism*
D005419:Flavonoids; D005960:Glucosides; D011427:Propiophenones; D002599:Chalcone; C104536:xanthohumol