[Studies on chemical constituents in spikes of Schizonepeta tenuifolia].
OBJECTIVE
To study the chemical constituents in the spikes of Schizonepeta tenuifolia.


METHODS
Compounds were isolated and purified with silica gel, ODS and Sephadex LH-20 gel column chromatography, and their structures were determined by using spectroscopic analysis including MS and NMR.


RESULTS
Nine compounds were isolated and identified as 5, 7-dihydroxy-6, 4'-dimethoxyflavone (1), 5, 7-dihydroxy-6, 3', 4'-trimethoxyflavone (2), ursolic acid (3), 3-hydroxy-4(8)-ene-p-menthane-3(9)-lactone (4), 5, 7, 4'-trihydroxyflavone (5), 5, 4'-dihydroxy-7-methoxyflavone (6), hesperidin (7), luteolin (8) and daucesterol (9).


CONCLUSIONS
Compounds 1, 2, 6 were first obtained from the spikes of S. tenuifolia.
Zhang
Yuan-hu
YH
Key Laboratory of Chemistry for Natural Products of Guizhou Province and Chinese Academy of Sciences, Guiyang. zhangyuanhu@263.net
Zhou
Lan
L
Shi
Ren-bing
RB
Guo
Ya-jian
YJ
Dong
Yu
Y
D047309:Flavones / Q000737:chemistry / Q000302:isolation & purification*; D035263:Flowering Tops / Q000737:chemistry; D019686:Lamiaceae / Q000737:chemistry*; D010946:Plants, Medicinal / Q000737:chemistry*
C522638:5,7-dihydroxy-6,3',4'-trimethoxyflavone; C522637:5,7-dihydroxy-6,4'-dimethoxyflavone; D047309:Flavones; C014568:genkwanin