Opaque coating of an intraocular lens and regression of iris neovascularization following injection of triamcinolone acetonide into the anterior chamber.
A pseudophakic patient presented with a vitreous haemorrhage and iris neovascularization associated with proliferative diabetic retinopathy. Vitrectomy with panretinal photocoagulation and intraocular gas tamponade of an iatrogenic break was performed. As an alternative to intravitreal injection into a gas-filled eye, triamcinolone acetonide was injected into the anterior chamber. Postoperatively, the visual acuity was reduced to light perception by an opaque coating of triamcinolone particles on the intraocular lens and iris which resolved over 2 months. By 4 months, the iris neovascularization had regressed completely. The use of intracameral triamcinolone in pseudophakic eyes may be associated with a transient loss of vision and prevent fundal visualization owing to triamcinolone coating of the intraocular lens.
Chen
Simon Dm
SD
Chen
Fred K
FK
Patel
Ck
C
D000867:Anterior Chamber / Q000187:drug effects*; D003930:Diabetic Retinopathy / Q000150:complications; D005260:Female; D005938:Glucocorticoids / Q000008:administration & dosage* / Q000378:metabolism; D006801:Humans; D007267:Injections; D007498:Iris / Q000098:blood supply*; D017075:Laser Coagulation; D007910:Lenses, Intraocular; D008875:Middle Aged; D009389:Neovascularization, Pathologic / Q000188:drug therapy* / Q000209:etiology; D019591:Pseudophakia / Q000378:metabolism; D014222:Triamcinolone Acetonide / Q000008:administration & dosage* / Q000378:metabolism; D014821:Vitrectomy; D014823:Vitreous Hemorrhage / Q000188:drug therapy / Q000209:etiology
D005938:Glucocorticoids; D014222:Triamcinolone Acetonide