[Role of anti-Müllerian hormone in follicle recruitment and maturation].
Anti-Müllerian hormone (AMH), a member of the TGF-beta family, plays a crucial role during male sexual differentiation. This paper reviews the role of anti-Müllerian hormone in the ovary. In vivo and in vitro studies showed that AMH has an inhibitory effect on primordial follicle recruitment and it decreases the sensitivity of follicles for the FSH-dependent selection for dominance. Besides its functional role in the ovary, the AMH serum level serves as an excellent candidate marker of ovarian reserve.
Visser
J
J
Department of Internal Medicine, Erasmus MC. Rotterdam, The Netherlands.
D000328:Adult; D054304:Anti-Mullerian Hormone; D005260:Female; D005640:Follicle Stimulating Hormone / Q000502:physiology; D006023:Glycoproteins / Q000097:blood / Q000502:physiology*; D006801:Humans; D006080:Ovarian Follicle / Q000502:physiology*; D010053:Ovary / Q000502:physiology; D013735:Testicular Hormones / Q000097:blood / Q000502:physiology*
D006023:Glycoproteins; D013735:Testicular Hormones; D054304:Anti-Mullerian Hormone; D005640:Follicle Stimulating Hormone