title: 18F-FDG PET in mucosa-associated lymphoid tissue (MALT) lymphoma.
abstract: To evaluate the sensitivity of 18-fluoro-2-deoxyglucose (18F-FDG) positron emission tomography (PET) in patients with mucosa-associated lymphoid tissue (MALT) lymphoma. A total of 32 patients with a histological diagnosis of extra-nodal MALT lymphoma were referred to the PET Centers in the last 2 years (2003 - 2004) and scanned with 18F-FDG-PET following standard procedures. Overall, the results of 50 18F-FDG-PET scans performed in either active disease state or in complete remission were reviewed. Sites of primary disease included stomach, lung, parotid, skin, orbit, mandible, esophagus and uterus. This study retrospectively enrolled 26 patients with known active disease. 18F-FDG-PET was true positive (TP) in 21/26 patients and false negative (FN) in 5/26. Sensitivity of 18F FDG-PET for extra-nodal MALT was 81%. The data show that 18FDG-PET is a useful diagnostic tool in order to stage, restage or monitor disease in patients with extra-nodal MALT lymphoma.
authors.affiliation: Institute of Hematology and Oncology Seragnoli, University of Bologna, Italy.
authors.forename: Lapo
authors.initials: L
authors.lastname: Alinari
authors.forename: Paolo
authors.initials: P
authors.lastname: Castellucci
authors.forename: Rebecca
authors.initials: R
authors.lastname: Elstrom
authors.forename: Valentina
authors.initials: V
authors.lastname: Ambrosini
authors.forename: Vittorio
authors.initials: V
authors.lastname: Stefoni
authors.forename: Cristina
authors.initials: C
authors.lastname: Nanni
authors.forename: Arnold
authors.initials: A
authors.lastname: Berkowitz
authors.forename: Monica
authors.initials: M
authors.lastname: Tani
authors.forename: Mohsen
authors.initials: M
authors.lastname: Farsad
authors.forename: Roberto
authors.initials: R
authors.lastname: Franchi
authors.forename: Stefano
authors.initials: S
authors.lastname: Fanti
authors.forename: Pier Luigi
authors.initials: PL
authors.lastname: Zinzani
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008223:Lymphoma / Q000175:diagnosis* / Q000000981:diagnostic imaging*; D018442:Lymphoma, B-Cell, Marginal Zone / Q000175:diagnosis* / Q000000981:diagnostic imaging; D008228:Lymphoma, Non-Hodgkin / Q000175:diagnosis / Q000000981:diagnostic imaging; D008297:Male; D008875:Middle Aged; D049268:Positron-Emission Tomography / Q000379:methods*; D019275:Radiopharmaceuticals; D012189:Retrospective Studies
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18