title: [Diagnosis and treatment of posttraumatic pseudolipomas. A retrospective analysis].
abstract: BACKGROUND
  Both trauma and lipomas are frequently encountered in day-to-day clinical practice. Although lipomas are defined both clinically and pathologically as benign fatty tissue tumours, their aetiology is still not clear.
  
  
  METHODS
  In this study 19 patients with 23 posttraumatic lipomas were analysed retrospectively with reference to ultrasound and MRI diagnosis, history, laboratory results and histopathological investigations.
  
  
  RESULTS
  The mean age of the patients was 50.5 years (+/-15.5). The causative soft tissue trauma dated back an average of 2.6 years. When the histories were taken, 16 of the 19 patients reported vast, slow-resorbing posttraumatic haematomas. Nine of the 23 lipomas were sited in the upper extremity, 3 in the lower extremity, 9 in the trunk and 2 in the face. All were located epifascially. In 22 cases the lipomas were excised, and in 1 case the lipoma was removed by liposuction. Histological examination demonstrated capsulated benign fatty tissue tumours in 19 cases and uncapsulated benign fatty tissue tumours in 4. The average body mass index (BMI) was 29 kg/m(2). Removal of the tumour resulted in a good aesthetic result in all patients.
  
  
  CONCLUSIONS
  The link between a blunt soft tissue injury and the development of a posttraumatic lipoma is still the subject of controversy; there are two mechanisms that seem more likely than any others proposed: (1) the "pseudolipoma" as the result of a prolapse of fatty tissue as an immediate result of trauma and (2) the development of a lipoma by way of differentiation of pre-adipocytes mediated by cytokines released by a posttraumatic haematoma. There appears to be a correlation between an increased partial thromboplastin time (PTT) and the development of posttraumatic lipomas. The generalised increase in the volume of body fat documented by the elevated BMI supports the idea that lipomas arise from the prolapse of adipose tissue. However, there is no single mechanistic explanation for the development of posttraumatic lipomas. They are probably caused by multiple factors and not by isolated pathological mechanisms.
authors.affiliation: Klinik für Plastische-, Hand- und Wiederherstellungschirurgie, Medizinische Hochschule Hannover, Carl-Neubergstr. 1, 30625 Hannover, Deutschland.
authors.forename: M C
authors.initials: MC
authors.lastname: Aust
authors.forename: M
authors.initials: M
authors.lastname: Spies
authors.forename: S
authors.initials: S
authors.lastname: Kall
authors.forename: P M
authors.initials: PM
authors.lastname: Vogt
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D015992:Body Mass Index; D003937:Diagnosis, Differential; D005260:Female; D006406:Hematoma / Q000150:complications / Q000473:pathology; D006801:Humans; D015187:Lipectomy; D008067:Lipoma / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012307:Risk Factors; D017695:Soft Tissue Injuries / Q000150:complications* / Q000473:pathology; D012983:Soft Tissue Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D014463:Ultrasonography; D014949:Wounds, Nonpenetrating / Q000150:complications* / Q000473:pathology