Conversion of indanone oximes into isocarbostyrils.
New and effective method for the Beckmann rearrangement of indanone oxime mesylate is described, in which a selective and controlled production of the isomeric isocarbostyrils is achieved.
Torisawa
Yasuhiro
Y
Faculty of Pharmacy, Takasaki University of Health and Welfare, 60 Naka-Orui, Takasaki, Gunma 370-0033, Japan. torisawa@takasaki-u.ac.jp
Aki
Shinji
S
Minamikawa
Jun-ichi
J
D007202:Indicators and Reagents; D007536:Isomerism; D007546:Isoquinolines / Q000138:chemical synthesis*; D008698:Mesylates / Q000737:chemistry*; D010091:Oximes / Q000737:chemistry*; D012997:Solvents; D014025:Titanium / Q000737:chemistry
D007202:Indicators and Reagents; D007546:Isoquinolines; D008698:Mesylates; D010091:Oximes; D012997:Solvents; C518622:indanone oxime mesylate; C008179:isocarbostyril; C030209:methanesulfonyl chloride; D014025:Titanium