title: Persistence of Cloquet's canal in normal healthy eyes.
abstract: OBJECTIVE
  Optic nerve head (ONH) structural imaging with state-of-the-art, high-speed, ultra-high-resolution optical coherence tomography (hsUHR-OCT).
  
  
  METHODS
  Observational cohort study.
  
  
  METHODS
  ONH centered 3-dimensional (94,371,840 voxel measurements in a 6- x 6- x 1.4-mm tissue volume) hsUHR-OCT data were obtained in one eye from each of six males and nine females normal healthy volunteers (40 +/- 9 years of age). The presence of structures projecting anteriorly from the disk into the vitreous was noted.
  
  
  RESULTS
  Structures were noted in 14 of 15 (93%) examined eyes, emanating from the rim of the ONH at the nasal inferior sector, presenting as thin tissue meandering into the vitreous.
  
  
  CONCLUSIONS
  Previous technologies provided limited visualization of ONH structures. The ability to scan the entire disk using 3-dimensional OCT (3D-OCT) in a high-density raster pattern reveals a high frequency of persistence of Cloquet's canal in the normal healthy eye.
authors.affiliation: UPMC Eye Center, Eye and Ear Institute, Department of Ophthalmology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA.
authors.forename: Larry
authors.initials: L
authors.lastname: Kagemann
authors.forename: Gadi
authors.initials: G
authors.lastname: Wollstein
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Ishikawa
authors.forename: Michelle L
authors.initials: ML
authors.lastname: Gabriele
authors.forename: Vivek J
authors.initials: VJ
authors.lastname: Srinivasan
authors.forename: Maciej
authors.initials: M
authors.lastname: Wojtkowski
authors.forename: Jay S
authors.initials: JS
authors.lastname: Duker
authors.forename: James G
authors.initials: JG
authors.lastname: Fujimoto
authors.forename: Joel S
authors.initials: JS
authors.lastname: Schuman
mesh_terms: D000328:Adult; D004628:Embryonic Structures / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D021621:Imaging, Three-Dimensional / Q000379:methods; D008297:Male; D009898:Optic Disk / Q000000981:diagnostic imaging*; D041623:Tomography, Optical Coherence; D014463:Ultrasonography; D014822:Vitreous Body / Q000000981:diagnostic imaging