title: Results of magnetic resonance imaging in 14 cats with meningoencephalitis.
abstract: Medical records and magnetic resonance (MR) images of 14 cats with inflammatory diseases affecting the central nervous system (CNS) were reviewed retrospectively. Cases included eight cats with feline infectious peritonitis and two cats with toxoplasmosis. Abnormalities affecting the CNS were observed in MR images in 10 (71%) cats. Intracranial lesions appeared as slightly hypointense foci in T1-weighted images in two (14%) cats, as hyperintense foci in T2-weighted images in seven (50%) cats and as hyperintense foci after intravenous administration of a gadolinium-based contrast medium in 10 (71%) cats. In six cats with lesions in T1- and/or T2-weighted images, additional lesions were visible in T1-weighted images obtained after gadolinium-based contrast medium administration. In three cats, lesions were visible only after contrast medium administration. In our study, MR imaging (MRI) did not appear to detect all cases of CNS inflammation in the population of cats with inflammatory cerebrospinal fluid (CSF); however, MRI adds information about the sites and morphology of intracranial lesions that should help to distinguish between neoplasia and inflammatory conditions and, possibly, between different inflammatory conditions.
authors.affiliation: Department of Veterinary Clinical Sciences, The Royal Veterinary College, University of London, Hawkshead Lane, North Mymms, Hertfordshire AL9 7TA, UK. arianna_negrin@yahoo.it
authors.forename: Arianna
authors.initials: A
authors.lastname: Negrin
authors.forename: Christopher R
authors.initials: CR
authors.lastname: Lamb
authors.forename: Rodolfo
authors.initials: R
authors.lastname: Cappello
authors.forename: Giunio B
authors.initials: GB
authors.lastname: Cherubini
mesh_terms: D000818:Animals; D002371:Cat Diseases / Q000134:cerebrospinal fluid / Q000175:diagnosis* / Q000473:pathology; D002415:Cats; D005260:Female; D019786:Gadolinium DTPA; D008279:Magnetic Resonance Imaging / Q000662:veterinary*; D008297:Male; D008590:Meningoencephalitis / Q000134:cerebrospinal fluid / Q000175:diagnosis / Q000662:veterinary*; D011996:Records / Q000662:veterinary; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D016781:Toxoplasmosis, Cerebral / Q000134:cerebrospinal fluid / Q000175:diagnosis / Q000662:veterinary*; D014730:Veterinary Medicine
chemical_list: D019786:Gadolinium DTPA