title: Reducing surgical site infections through a multidisciplinary computerized process for preoperative prophylactic antibiotic administration.
abstract: BACKGROUND
  Surgical site infections (SSIs) result in significant postoperative morbidity and mortality. Although many of these infections can be prevented by timely administration of preoperative antibiotics, data suggest that many patients do not receive such therapy.
  
  
  METHODS
  A multidisciplinary team was convened that reviewed published guidelines, made antibiotic recommendations, and addressed administration issues. Responsibility for antibiotic administration was shifted from preoperative nursing staff to the anesthetist. Electronic quick orders were developed to encourage appropriate antibiotic selection and simplify order creation.
  
  
  RESULTS
  Timely administration of preoperative antibiotics improved from 51% to 98% from February 2005 to February 2006. Appropriate antibiotic administered improved from 78% to 94%. The clean wound infection rate decreased from 2.7% to 1.4% over the same time period.
  
  
  CONCLUSIONS
  A multidisciplinary approach to prophylactic antibiotic use, including computer-guided decision support, facilitates appropriate preoperative antibiotic use, resulting in a significant decrease in surgical wound infections.
authors.affiliation: Department of Surgery, Atlanta Veterans Affairs Medical Center, Decatur, GA 30033, USA. Alexandra.Webb@med.va.gov
authors.forename: Alexandra L B
authors.initials: AL
authors.lastname: Webb
authors.forename: Rene L
authors.initials: RL
authors.lastname: Flagg
authors.forename: Aaron S
authors.initials: AS
authors.lastname: Fink
mesh_terms: D000761:Anesthesia Department, Hospital / Q000592:standards; D019072:Antibiotic Prophylaxis / Q000379:methods* / Q000592:standards; D002985:Clinical Protocols; D020000:Decision Support Systems, Clinical / Q000458:organization & administration; D005845:Georgia; D006787:Hospitals, Veterans / Q000592:standards*; D006801:Humans; D008332:Management Quality Circles; D016347:Medical Records Systems, Computerized; D010607:Pharmacy Service, Hospital / Q000592:standards; D011300:Preoperative Care / Q000592:standards*; D013530:Surgical Wound Infection / Q000517:prevention & control*