title: Comparison of optic disk and retinal nerve fiber layer thickness in nonglaucomatous and glaucomatous patients with high myopia.
abstract: OBJECTIVE
  To assess the optic nerve head (ONH) by optical coherence tomography (OCT), confocal scanning laser ophthalmoscopy (CSLO), and the retinal nerve fiber layer (RNFL) by OCT and scanning laser polarimetry (GDx) in highly myopic subjects.
  
  
  METHODS
  Observational cross-sectional study.
  
  
  METHODS
  Thirty-five eyes of highly myopic individuals without glaucoma and 17 eyes of highly myopic patients with glaucoma were included in this study. All patients had myopia higher than 5.0 diopters and ocular axial length higher than 25 mm. In those patients without glaucoma, the intraocular pressure (IOP) was less than 21 mm Hg.
  
  
  RESULTS
  Mean (SD) OCT cup-to-disk area ratio was 0.45 (0.30) and 0.58 (0.29) in the nonglaucomatous and glaucomatous subjects, respectively (P = .22); CSLO cup-to-disk area ratio was 0.27 (0.27) and 0.24 (0.23), respectively (P = .75); and OCT-RNFL was 65.2 (26.2) microm and 56.8 (28.6) microm (P = .43).
  
  
  CONCLUSIONS
  OCT, CSLO, and GDx are not useful to discriminate nonglaucomatous and glaucomatous subjects that have high myopia.
authors.affiliation: Glaucoma Service, Department of Ophthalmology, Federal University of São Paulo (UNIFESP), São Paulo, Brazil. gustavobmelo@yahoo.com.br
authors.forename: Gustavo B
authors.initials: GB
authors.lastname: Melo
authors.forename: Rodrigo D
authors.initials: RD
authors.lastname: Libera
authors.forename: Aline S
authors.initials: AS
authors.lastname: Barbosa
authors.forename: Lia M G
authors.initials: LM
authors.lastname: Pereira
authors.forename: Larissa M
authors.initials: LM
authors.lastname: Doi
authors.forename: Luiz A S
authors.initials: LA
authors.lastname: Melo
mesh_terms: D000328:Adult; D003430:Cross-Sectional Studies; D003941:Diagnostic Techniques, Ophthalmological; D005901:Glaucoma / Q000175:diagnosis*; D006801:Humans; D007429:Intraocular Pressure; D007834:Lasers; D047728:Myopia, Degenerative / Q000175:diagnosis*; D009412:Nerve Fibers / Q000473:pathology*; D009887:Ophthalmoscopy; D009898:Optic Disk / Q000473:pathology*; D012165:Retinal Ganglion Cells / Q000473:pathology*; D041623:Tomography, Optical Coherence