title: [Angiosarcoma in chronic lymphedema].
abstract: Angiosarcoma that develops on a limb with chronic lymphedema is called Stewart-Treves syndrome. This typically appears as a complication of a long course lymphedema located on the arm, after mastectomy and/or radiotherapy due to breast cancer. There are cases of Stewart-Treves syndrome in chronic lymphedema in the upper limb contralateral to the breast treated for cancer and in chronic lymphedema of the leg. We present two cases of this syndrome. The first corresponds to a typical syndrome of Stewart-Treves in an 83-year-old woman who was diagnosed of angiosarcoma in a chronic lymphedema territory secondary to mastectomy and radiotherapy due to breast cancer. The second case is much rarer, since it is a case of diffuse angiosarcoma of the leg in a 42-year-old man with a history of lymphedema. Due to the aggressive nature of this syndrome, knowledge and research on its treatment are necessary.
authors.affiliation: Servicio de Dermatología, Hospital Universitario Reina Sofía, Córdoba, España. alfonsobujaldon@yahoo.es
authors.forename: Alfonso
authors.initials: A
authors.lastname: Rodríguez-Bujaldón
authors.forename: Maria Carmen
authors.initials: MC
authors.lastname: Vázquez-Bayo
authors.forename: Manolo
authors.initials: M
authors.lastname: Galán-Gutiérrez
authors.forename: Rafael
authors.initials: R
authors.lastname: Jiménez-Puya
authors.forename: Antonio
authors.initials: A
authors.lastname: Vélez García-Nieto
authors.forename: José Carlos
authors.initials: JC
authors.lastname: Moreno-Giménez
authors.forename: Alfredo
authors.initials: A
authors.lastname: Vidal-Jiménez
authors.forename: Elisa
authors.initials: E
authors.lastname: Barroso-Casamitjana
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000903:Antibiotics, Antineoplastic / Q000008:administration & dosage / Q000627:therapeutic use; D018906:Antineoplastic Agents, Alkylating / Q000008:administration & dosage / Q000627:therapeutic use; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001132:Arm; D004317:Doxorubicin / Q000008:administration & dosage / Q000627:therapeutic use; D005260:Female; D006394:Hemangiosarcoma / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology / Q000532:radiotherapy; D006801:Humans; D007069:Ifosfamide / Q000008:administration & dosage / Q000627:therapeutic use; D007150:Immunohistochemistry; D007866:Leg; D008209:Lymphedema / Q000150:complications*; D008297:Male; D012867:Skin / Q000473:pathology; D012878:Skin Neoplasms / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology / Q000473:pathology / Q000532:radiotherapy; D016896:Treatment Outcome
chemical_list: D000903:Antibiotics, Antineoplastic; D018906:Antineoplastic Agents, Alkylating; D004317:Doxorubicin; D007069:Ifosfamide