title: Development of a gel-simulation model and generation of standard tables for the complete extirpation of benign breast lesions with vacuum assisted biopsy under ultrasound guidance.
abstract: In combination with high-resolution ultrasound (US), vacuum-assisted biopsy (VB) techniques can be used for accurate diagnosis confirmation and therapeutic minimally invasive removal of benign breast lesions. We developed a gel-simulation model to imitate the removal of benign breast lesions (e.g., fibroadenoma) with VB from a turkey breast-phantom. Bilobular US-sensitive models in the form of a fibroadenoma were manufactured from flexible, cuttable synthetic material (longitudinal diameters of 4-20 mm). They were implanted in turkey meat and vacuum biopsied under 2-D and 3-D imaging with 11G and 8 G needles. The minimum number of cylinders removed per tumour volume, the maximum complete excision tumour size and the optimum needle gauge were determined. Lesions with a longitudinal diameter of up to 10 to 12 mm could be removed with the 11G needle, those up to 20 mm with the 8G needle. The values for the correct needle size, number of cylinders per tumour size to be removed produced with the gel turkey phantoms provide a reference for clinicians performing VB with total excision intent. VB is suitable for the removal of benign lesions with a diameter of up to 20 mm.
authors.affiliation: Department of Gynaecology and Obstetrics, Breast Centre, University of Tuebingen, Tuebingen, Germany.
authors.forename: Ute
authors.initials: U
authors.lastname: Krainick-Strobel
authors.forename: Ina
authors.initials: I
authors.lastname: Majer
authors.forename: Birte
authors.initials: B
authors.lastname: Huber
authors.forename: Christian
authors.initials: C
authors.lastname: Gall
authors.forename: Bernhard
authors.initials: B
authors.lastname: Krämer
authors.forename: Ines
authors.initials: I
authors.lastname: Gruber
authors.forename: Tanja
authors.initials: T
authors.lastname: Fehm
authors.forename: Jens
authors.initials: J
authors.lastname: Huober
authors.forename: Helmut
authors.initials: H
authors.lastname: Hierlemann
authors.forename: Michael
authors.initials: M
authors.lastname: Doser
authors.forename: Gabriele
authors.initials: G
authors.lastname: Meyberg-Solomayer
authors.forename: Jürgen
authors.initials: J
authors.lastname: Hoffmann
authors.forename: Diethelm
authors.initials: D
authors.lastname: Wallwiener
authors.forename: Markus
authors.initials: M
authors.lastname: Hahn
mesh_terms: D000818:Animals; D001707:Biopsy, Needle / Q000379:methods*; D001940:Breast / Q000601:surgery; D001943:Breast Neoplasms / Q000000981:diagnostic imaging / Q000601:surgery*; D005260:Female; D018226:Fibroadenoma / Q000000981:diagnostic imaging / Q000601:surgery*; D005782:Gels; D021621:Imaging, Three-Dimensional; D019060:Minimally Invasive Surgical Procedures / Q000379:methods; D009339:Needles; D019047:Phantoms, Imaging; D012826:Silicone Elastomers; D014422:Turkeys; D016217:Ultrasonography, Mammary / Q000379:methods*; D014618:Vacuum
chemical_list: D005782:Gels; D012826:Silicone Elastomers