[Levels of selected organochlorine insecticides, polychlorinated biphenyls, phthalates and perfluorinated aliphatic substances in blood--Polish WWF study].
In June 2004, blood samples of fifteen volunteers were analyzed for presence of selected groups of chemical contaminants. The aim of this survey organized by WWF Poland (World Wildlife Fund) was highlighting the problem of man-made, persistent and bioaccumulative chemicals constantly present in surrounding environment and in our tissues. It was a part of European WWF "Detox" campaign supporting proposal of a new EU regulation that should lead to the identification and phasing out of the most harmful chemicals (known as REACH). Three laboratories in Czech Republic, Sweden and Belgium have analyzed blood samples for presence of the following groups of contaminants: organochlorine compounds (pesticides and polychlorinated pesticides), phthalates and perfluorinated aliphatic substances. The total number of single chemicals found in the blood samples was 25, that represents 64% of the 39 chemicals looked for. The average number of compounds found in the samples was 21 (from 19 to 22). Among organochlorine compounds analyzed, the predominant chemical found in the highest concentration was p,p'-DDE (range from 130 to 1310 ng/g of fat), which similarly like p,p'-DDT, beta-HCH, and HCB (concentrations ranging from 6,4 to 46 ng/g of fat) was present in every person's blood. Among analyzed polychlorinated biphenyls, in all samples the following congeners have been present: PCB-118, PCB-138, PCB-153, and PCB-180 (concentrations ranging from 3,7 to 61 ng/g of fat). The two predominant phtalates from total eight analyzed present in all samples were di(2-ethylhexyl)phthalate (DEHP) (concentration range from 49 to 293 ng/g of blood) and diisobutyl phthalate (DIBP) (concentration range from 10 to 63 ng/g of blood). Among fifteen perfluorinated aliphatic substances analyzed, six have been present in each single sample (perfluorohexanesulfonic acid - PFHxS, perfluorooctanoic acid - PFOA, perfluorooctane-sulfonic acid - PFOS, perfluorooctanesulfonylamide - PFOSA, perfluorononanoic acid - PFNA, and perfluorododecanoic acid - PFDA). The predominant compound in this class of contaminants was PFOS with the concentration ranging from 4,4 to 14 ng/ml of blood. The limited number of samples does not allow for making an analysis of potential impact of different factors on concentrations of particular contaminants in human blood. Results obtained in this survey confirm the ubiquitous contamination by a cocktail of hazardous chemicals of every person tested. Humans being a part of the environment are being contaminated with the same chemicals which are present in surrounding air, water, food, consumer articles, etc.
Struciński
Paweł
P
Zakład Toksykologii Srodowiskowej Państwowy Zakład Higieny 00-791 Warszawa, ul. Chocimska 24. pstrucinski@pzh.gov.pl
Góralczyk
Katarzyna
K
Ludwicki
Jan K
JK
Czaja
Katarzyna
K
Hernik
Agnieszka
A
Korcz
Wojciech
W
D000328:Adult; D004784:Environmental Monitoring / Q000706:statistics & numerical data*; D004785:Environmental Pollutants / Q000097:blood* / Q000737:chemistry; D005062:European Union / Q000458:organization & administration; D005260:Female; D005466:Fluorocarbons / Q000097:blood*; D006801:Humans; D006843:Hydrocarbons, Chlorinated / Q000097:blood*; D007306:Insecticides / Q000097:blood*; D008297:Male; D008875:Middle Aged; D010795:Phthalic Acids / Q000097:blood*; D011044:Poland; D011078:Polychlorinated Biphenyls / Q000097:blood*
D004785:Environmental Pollutants; D005466:Fluorocarbons; D006843:Hydrocarbons, Chlorinated; D007306:Insecticides; D010795:Phthalic Acids; D011078:Polychlorinated Biphenyls