title: Severe dehydration and acute renal failure associated with external ventricular drainage of cerebrospinal fluid in children.
abstract: We report three paediatric cases of severe dehydration and hyponatraemia with circulatory compromise associated with the use of external ventricular drainage of cerebrospinal fluid. Two of the children had cardiac arrests. All were successfully resuscitated. While there were additional factors that contributed to other fluid losses, and fluid balance data are incomplete, these cases highlight a need for increased vigilance when managing children with external ventricular drains.
authors.affiliation: Paediatric Intensive Care Unit, Women's and Children's Hospital, Adelaide, South Australia.
authors.forename: S
authors.initials: S
authors.lastname: Simpson
authors.forename: M
authors.initials: M
authors.lastname: Yung
authors.forename: A
authors.initials: A
authors.lastname: Slater
mesh_terms: D000168:Acrocephalosyndactylia / Q000150:complications / Q000628:therapy; D058186:Acute Kidney Injury / Q000209:etiology*; D002552:Cerebral Ventricles / Q000502:physiology*; D002555:Cerebrospinal Fluid / Q000502:physiology*; D003394:Craniofacial Dysostosis / Q000150:complications / Q000628:therapy; D003681:Dehydration / Q000209:etiology*; D004322:Drainage / Q000009:adverse effects; D005260:Female; D006323:Heart Arrest / Q000209:etiology; D006801:Humans; D006849:Hydrocephalus / Q000150:complications; D007010:Hyponatremia / Q000209:etiology; D007223:Infant; D007427:Intracranial Pressure / Q000502:physiology; D008297:Male; D012151:Resuscitation; D014883:Water-Electrolyte Imbalance / Q000209:etiology