title: Adaptation of the standard 12-lead electrocardiogram system dedicated to the analysis of atrial fibrillation.
abstract: OBJECTIVE
  The objective of the study was to design a lead system aimed at studying atrial fibrillation (AF), while being anchored to the standard 12-lead system.
  
  
  METHODS
  The location of 4 of the 6 precordial electrodes was optimized while leaving the remaining 5 of the 9 electrodes of the standard 12-lead system in place. The analysis was based on episodes of 11 different variants of AF simulated by a biophysical model of the atria positioned inside an inhomogeneous thorax. The optimization criterion used was derived from the singular value decomposition of the data matrices.
  
  
  RESULTS
  While maintaining VR, VL, VF, V1 and V4, the 4 new electrode positions increased the ratio of the eighth and the first singular values of the data matrices of the new configuration about 5-fold compared with that of the conventional electrode positions.
  
  
  CONCLUSIONS
  The adapted lead system produces a more complete view on AF compared with that of the standard 12-lead system.
authors.affiliation: Signal Processing Institute, Swiss Federal Institute of Technology Lausanne, Lausanne, Switzerland. zenichi.ihara@epfl.ch
authors.forename: Zenichi
authors.initials: Z
authors.lastname: Ihara
authors.forename: Adriaan
authors.initials: A
authors.lastname: van Oosterom
authors.forename: Vincent
authors.initials: V
authors.lastname: Jacquemet
authors.forename: Rudi
authors.initials: R
authors.lastname: Hoekema
mesh_terms: D001281:Atrial Fibrillation / Q000175:diagnosis*; D018780:Body Surface Potential Mapping / Q000295:instrumentation / Q000379:methods*; D003198:Computer Simulation; D003936:Diagnosis, Computer-Assisted / Q000295:instrumentation / Q000379:methods*; D004566:Electrodes; D006325:Heart Atria / Q000503:physiopathology*; D006329:Heart Conduction System / Q000503:physiopathology*; D006801:Humans; D008955:Models, Cardiovascular; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity