Staged resection for a ruptured hepatoblastoma: a 6-year follow-up.
Hepatoblastoma (HB) is a rare germ cell tumour of childhood usually presenting with progressive abdominal distention. However, presentation as acute abdomen is a rare occurrence and is secondary to spontaneous rupture. This presentation carries high mortality. To our knowledge, six cases of ruptured hepatoblastoma have previously been reported, although the long-term outcome has not been clear. We report a case of ruptured HB who was managed by initial control of haemorrhage by laparotomy followed by chemotherapy with high-risk hepatoblastoma protocol as per SIOPEL 2 (cisplatin, carboplatin and doxorubicin) and a staged hepatectomy 5 months later. Patient is currently disease free at 6-year follow-up. Staged hepatectomy after initial control of haemorrhage does not preclude a curative resection.
Madanur
Mansoor Ahmed
MA
Kings College Hospital, Denmark Hill, London, SE5 9RS, UK. mansoor73@yahoo.com
Battula
Narendra
N
Davenport
Mark
M
Dhawan
Anil
A
Rela
Mohamed
M
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D017024:Chemotherapy, Adjuvant; D006471:Gastrointestinal Hemorrhage / Q000209:etiology / Q000601:surgery*; D006498:Hepatectomy / Q000379:methods*; D018197:Hepatoblastoma / Q000150:complications / Q000188:drug therapy / Q000473:pathology / Q000601:surgery*; D006801:Humans; D007223:Infant; D008113:Liver Neoplasms / Q000150:complications / Q000188:drug therapy / Q000473:pathology / Q000601:surgery*; D008297:Male; D012422:Rupture, Spontaneous