title: Radial artery diameter and vasodilatory properties after transradial coronary angiography.
abstract: BACKGROUND
  The radial artery is proposed as an alternative conduit in coronary revascularization. During the last years the transradial approach has, in many centers, emerged as the preferred technique in percutaneous diagnostic and interventional coronary procedures. This induces a trauma to the radial artery that possibly could influence its suitability as a bypass graft. In this study we assessed by ultrasound the long-term effects of transradial coronary angiography on the radial artery diameter and vasodilatory properties.
  
  
  METHODS
  Thirty patients were examined with high resolution ultrasound 10 to 14 months after a transradial coronary angiography. Radial artery baseline diameter and response to flow-mediated (FMD) and nitroglycerin-mediated vasodilation (NMD) were examined in the right radial artery with the unexposed left radial artery as control.
  
  
  RESULTS
  Right radial artery diameter was reduced compared with the left radial artery (2.58 +/- 0.38 vs 2.71 +/- 0.32 mm, p < 0.01). Both FMD and NMD were preserved in the exposed artery (FMD 8.4 +/- 8.0 vs 8.0 +/- 6.1%, NMD 15.5 +/- 6.8 vs 16.7 +/- 6.6%, both ns). Due to the reduced baseline diameter, the right radial lumen diameter remained significantly smaller after vasodilatory stimuli. Large interindividual differences were demonstrated.
  
  
  CONCLUSIONS
  The radial artery diameter is diminished one year after transradial coronary angiography while vasodilatory properties are preserved. The preserved vasodilatory capacity could favorably influence the suitability of the artery as bypass graft. However, with the long-term structural changes induced by transradial angiography, use of a catheter-exposed radial artery as a conduit in coronary artery revascularization should not be strongly recommended. With ultrasound, both structure and vasodilatory properties of a catheterization-exposed radial artery may be assessed in case the artery is considered as bypass material.
authors.affiliation: Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway.
authors.forename: Erik
authors.initials: E
authors.lastname: Madssen
authors.forename: Petter
authors.initials: P
authors.lastname: Haere
authors.forename: Rune
authors.initials: R
authors.lastname: Wiseth
mesh_terms: D000368:Aged; D017023:Coronary Angiography / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D005996:Nitroglycerin / Q000494:pharmacology; D017534:Radial Artery / Q000000981:diagnostic imaging* / Q000502:physiology*; D014463:Ultrasonography; D014664:Vasodilation / Q000187:drug effects / Q000502:physiology; D014665:Vasodilator Agents / Q000494:pharmacology
chemical_list: D014665:Vasodilator Agents; D005996:Nitroglycerin