Vagus nerve stimulation for intractable seizures in children.
Forty-three children less than 12 years of age having intractable seizures were treated with vagus nerve stimulation. Five children were monitored for <12 months, 16 children for 12 to 17 months, and 22 children for > or =18 months with overall median seizure reduction of 55%. Thirty-seven percent had at least 90% reduction. Vagus nerve stimulation was effective in children with generalized, mixed, and partial medically refractory seizures.
Saneto
Russell P
RP
Division of Pediatric Neurology, Children's Hospital and Regional Medical Center/University of Washington, Seattle, WA 98105, USA. russ.saneto@seattlechildrens.org
Sotero de Menezes
Marcio A
MA
Ojemann
Jeffrey G
JG
Bournival
Brian D
BD
Murphy
Patricia J
PJ
Cook
William B
WB
Avellino
Anthony M
AM
Ellenbogen
Richard G
RG
D000367:Age Factors; D002648:Child; D004599:Electric Stimulation Therapy; D004567:Electrodes, Implanted; D004827:Epilepsy / Q000628:therapy*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D012189:Retrospective Studies; D016896:Treatment Outcome; D014630:Vagus Nerve