Complanadines C and D, new dimeric alkaloids from Lycopodium complanatum.
Two new dimeric Lycopodium alkaloids, complanadines C (1) and D (2), have been isolated from the club moss Lycopodium complanatum, and the structures and relative stereochemistry of 1 and 2 were elucidated on the basis of the spectral data. Complanadine D (2) enhanced mRNA expression for NGF.
Ishiuchi
Kan'ichiro
K
Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo 060-0812, Japan.
Kubota
Takaaki
T
Mikami
Yuzuru
Y
Obara
Yutaro
Y
Nakahata
Norimichi
N
Kobayashi
Jun'ichi
J
D000470:Alkaloids / Q000737:chemistry* / Q000302:isolation & purification; D019281:Dimerization; D006576:Heterocyclic Compounds, 4 or More Rings / Q000737:chemistry* / Q000302:isolation & purification*; D032502:Lycopodium / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy / Q000379:methods / Q000592:standards; D008958:Models, Molecular; D008968:Molecular Conformation; D012015:Reference Standards; D013237:Stereoisomerism
D000470:Alkaloids; D006576:Heterocyclic Compounds, 4 or More Rings; C517127:complanadine C; C517128:complanadine D