title: Successful double bioprosthetic valve replacement in a 64-year-old man with carcinoid syndrome and bipolar disorder: case report.
abstract: The case is described of a 64-year-old man with bipolar disorder and severe carcinoid heart disease who required a double valve replacement. Multidisciplinary team involvement and extensive preoperative investigations resulted in a successful regimen which prevented reactivation of carcinoid syndrome and avoided the serious side effects of lantreotide and lithium therapy. In addition, two bioprosthetic valves were used, thereby avoiding the potential complications of anticoagulation in a patient with known hepatic metastases.
authors.affiliation: Department of Cardiac Surgery, Royal Brompton Hospital, London, UK. stang@doctors.org.uk
authors.forename: Sarah S
authors.initials: SS
authors.lastname: Tang
authors.forename: Michael Y
authors.initials: MY
authors.lastname: Henein
authors.forename: Anthony
authors.initials: A
authors.lastname: De Souza
mesh_terms: D001705:Bioprosthesis; D001714:Bipolar Disorder / Q000150:complications*; D004452:Echocardiography; D006333:Heart Failure / Q000175:diagnosis / Q000209:etiology / Q000601:surgery; D006338:Heart Neoplasms / Q000150:complications / Q000473:pathology / Q000601:surgery*; D006350:Heart Valve Prosthesis; D019918:Heart Valve Prosthesis Implantation / Q000295:instrumentation; D006801:Humans; D008113:Liver Neoplasms / Q000150:complications / Q000556:secondary; D008279:Magnetic Resonance Imaging; D008297:Male; D008303:Malignant Carcinoid Syndrome / Q000150:complications / Q000473:pathology / Q000601:surgery*; D008875:Middle Aged; D011665:Pulmonary Valve Insufficiency / Q000150:complications / Q000175:diagnosis / Q000601:surgery; D014057:Tomography, X-Ray Computed; D014262:Tricuspid Valve Insufficiency / Q000150:complications / Q000175:diagnosis / Q000601:surgery