title: [Comparison of antibacterial efficacy of 1 and 25% concentration of Metrogil-denta for inflammatory periodontal disease treatment].
abstract: The study was made of Metrogil-denta (MD) with a stable 0.25% chlorhexidine concentration and metronidazole concentration 1.0% for prevention and 25% for inflammatory periodontal disease treatment. Results of their use in 76 patients are presented. MD with 1% metronidazole failed to eliminate aerobic and anaerobic microflora completely. Bactericidal effect of Metrogil-denta was seen only in 25% metronidazole concentration.
authors.forename: A I
authors.initials: AI
authors.lastname: Grudianov
authors.forename: V V
authors.initials: VV
authors.lastname: Ovchinnikova
authors.forename: N A
authors.initials: NA
authors.lastname: Dmitrieva
mesh_terms: D000328:Adult; D000368:Aged; D000890:Anti-Infective Agents / Q000008:administration & dosage* / Q000627:therapeutic use; D001420:Bacteria, Aerobic / Q000187:drug effects* / Q000302:isolation & purification; D001421:Bacteria, Anaerobic / Q000187:drug effects* / Q000302:isolation & purification; D001424:Bacterial Infections / Q000188:drug therapy* / Q000382:microbiology; D002710:Chlorhexidine / Q000008:administration & dosage / Q000627:therapeutic use; D004305:Dose-Response Relationship, Drug; D004359:Drug Therapy, Combination; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008795:Metronidazole / Q000008:administration & dosage* / Q000627:therapeutic use; D008875:Middle Aged; D010518:Periodontitis / Q000188:drug therapy* / Q000382:microbiology; D016896:Treatment Outcome
chemical_list: D000890:Anti-Infective Agents; D008795:Metronidazole; D002710:Chlorhexidine