title: Central venous pulse pressure analysis using an R-synchronized pressure measurement system.
abstract: OBJECTIVE
  The information derived from central venous catheters is underused. We developed an EKG-R synchronization and averaging system to obtained distinct CVP waveforms and analyzed components of these.
  
  
  METHODS
  Twenty-five paralyzed surgical patients undergoing CVP monitoring under mechanical ventilation were studied. CVP and EKG signals were analyzed employing our system, the mean CVP and CVP at end-diastole during expiration were compared, and CVP waveform components were measured using this system.
  
  
  RESULTS
  CVP waveforms were clearly visualized in all patients. They showed the a peak to be 1.8+/- 0.7 mmHg, which was the highest of three peaks, and the x trough to be lower than the y trough (-1.6+/- 0.7 mmHg and -0.9+/- 0.5 mmHg, respectively), with a mean pulse pressure of 3.4 mmHg. The difference between the mean CVP and CVP at end-diastole during expiration was 0.58+/- 0.81 mmHg.
  
  
  CONCLUSIONS
  The mean CVP can be used as an index of right ventricular preload in patients under mechanical ventilation with regular sinus rhythm. Our newly developed system is useful for clinical monitoring and for education in circulatory physiology.
authors.affiliation: Department of Anesthesiology & ICM, Kawasaki Medical School, 577 Matsushima, Kurashiki-city, Okayama, 701-0192, Japan. fujitay@med.kawasaki-m.ac.jp
authors.forename: Yoshihisa
authors.initials: Y
authors.lastname: Fujita
authors.forename: Daisuke
authors.initials: D
authors.lastname: Hayashi
authors.forename: Shinya
authors.initials: S
authors.lastname: Wada
authors.forename: Naoki
authors.initials: N
authors.lastname: Yoshioka
authors.forename: Takeshi
authors.initials: T
authors.lastname: Yasukawa
authors.forename: Gunther
authors.initials: G
authors.lastname: Pestel
mesh_terms: D001795:Blood Pressure Determination / Q000379:methods* / Q000706:statistics & numerical data; D002496:Central Venous Pressure; D004562:Electrocardiography / Q000706:statistics & numerical data; D006801:Humans; D008991:Monitoring, Physiologic / Q000379:methods* / Q000706:statistics & numerical data