title: First blueprint, now bricks: DNA as construction material on the nanoscale.
abstract: For the most part DNA was considered Nature's instruction manual for life leading to the popular description 'blueprint of life'. However, DNA is now taking on a new aspect where it is finding use as a construction element for architecture on the nanoscale. This tutorial review addresses the importance of building ordered structures with DNA on the nanoscale, the underlying principles and approaches to build such scaffolds, the current limitations and the anticipated trajectory of the area. This is would be of interest to the chemical biology, supramolecular and bioengineering communities in particular.
authors.affiliation: National Centre for Biological Sciences, TIFR, GKVK, Bellary Road, Bangalore 560 065, India.
authors.forename: Sethuramasundaram
authors.initials: S
authors.lastname: Pitchiaya
authors.forename: Yamuna
authors.initials: Y
authors.lastname: Krishnan
mesh_terms: D004247:DNA / Q000737:chemistry*; D049329:Nanostructures / Q000737:chemistry* / Q000648:ultrastructure; D009690:Nucleic Acid Conformation
chemical_list: D004247:DNA