title: Comparison of PENELOPE Monte Carlo dose calculations with Fricke dosimeter and ionization chamber measurements in heterogeneous phantoms (18 MeV electron and 12 MV photon beams).
abstract: Different measurements of depth-dose curves and dose profiles were performed in heterogeneous phantoms and compared to dose distributions calculated by a Monte Carlo code. These heterogeneous phantoms consisted of lung and/or bone heterogeneities. Irradiations and simulations were carried out for an 18 MeV electron beam and a 12 MV photon beam. Depth-dose curves were measured with Fricke dosimeters and with plane and cylindrical ionization chambers. Dose profiles were measured with a small cylindrical ionization chamber at different depths. The LINAC was modelled using the PENELOPE code and phase space files were used as input data for the calculations of the dose distributions in every simulation. The detectors (Fricke dosimeters and ionization chambers) were not modelled in the geometry. There is generally a good agreement between the measurements and PENELOPE. Some discrepancies exist, near interfaces, between the ionization chamber and PENELOPE due to the attenuation of the lower energy electrons by the wall of the ionization chamber.
authors.affiliation: CEA-Saclay, DETECS/LNHB, 91190 Gif sur Yvette, France. leone.blazy@cea.fr
authors.forename: L
authors.initials: L
authors.lastname: Blazy
authors.forename: D
authors.initials: D
authors.lastname: Baltes
authors.forename: J M
authors.initials: JM
authors.lastname: Bordy
authors.forename: D
authors.initials: D
authors.lastname: Cutarella
authors.forename: F
authors.initials: F
authors.lastname: Delaunay
authors.forename: J
authors.initials: J
authors.lastname: Gouriou
authors.forename: E
authors.initials: E
authors.lastname: Leroy
authors.forename: A
authors.initials: A
authors.lastname: Ostrowsky
authors.forename: S
authors.initials: S
authors.lastname: Beaumont
mesh_terms: D001822:Body Burden; D004583:Electrons / Q000627:therapeutic use; D006801:Humans; D009010:Monte Carlo Method; D019047:Phantoms, Imaging; D017785:Photons / Q000627:therapeutic use; D011874:Radiometry / Q000295:instrumentation* / Q000379:methods*; D011879:Radiotherapy Dosage; D011880:Radiotherapy Planning, Computer-Assisted / Q000379:methods*; D020266:Radiotherapy, Conformal / Q000379:methods*; D012062:Relative Biological Effectiveness; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D012984:Software; D012986:Software Validation