title: [Clinical usage of parallel imaging of head three-dimensional MR image for analysis of VSRAD: a comparison of imaging statistical analytic results in SENSE acquisition method shortening acquisition time versus conventional acquisition method].
abstract: Voxel-based Specific Regional Analysis System for Alzheimer's Disease (VSRAD) has developed recently as an adjunctive diagnostic tool for early Alzheimer-type dementia (ATD), using three-dimensional (3D) MRI with statistical parametric mapping (SPM), and for the objective evaluation of brain atrophy. However, it takes more than five minutes to acquire MRI data by the 3D gradient echo method (3D FFE), resulting in low-throughput performance and motion artifact. These problems interrupt the application of daily MRI study. In this study, we recruited 20 patients suspected of having ATD who then underwent continuous 3D FFE MRI studies with and without the SENSE method. It was found that the VSRAD results of MRI data with SENSE were nearly to equal to those without SENSE, in spite of the prediction of a decline in source-to-noise ratio due to the reduction factor in the SENSE method.
authors.affiliation: Department of Radiology, Hakujikai Memorial General Hospital.
authors.forename: Masanobu
authors.initials: M
authors.lastname: Nakamura
authors.forename: Nobuhiro
authors.initials: N
authors.lastname: Ikeda
authors.forename: Toshikazu
authors.initials: T
authors.lastname: Tsuboko
authors.forename: Ichirou
authors.initials: I
authors.lastname: Yoshikawa
authors.forename: Sunao
authors.initials: S
authors.lastname: Mizumura
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000544:Alzheimer Disease / Q000175:diagnosis*; D001284:Atrophy; D001921:Brain / Q000473:pathology; D005260:Female; D006801:Humans; D021621:Imaging, Three-Dimensional; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged