Gamma knife radiosurgery for epilepsy related to dysembryoplastic neuroepithelial tumor.
Dysembryoplastic neuroepithelial tumor (DNT) is a well-known epileptogenic lesion with favorable seizure outcome after surgical resection. However, sometimes surgery may be difficult technically, and epilepsy may continue throughout the patient's lifetime despite surgical intervention. We report a case of intractable epilepsy related to DNT that was treated with gamma knife radiosurgery (GKRS). The frequency of seizure was reduced remarkably after GKRS, and finally a seizure-free state was accomplished in two years. Neuropsychological tests also showed improvement. It is suggested that GKRS may be an effective and less invasive alternative treatment for the patients in whom surgical treatment is difficult.
Kwon
Ki-Hun
KH
Department of Neurosurgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Lee
Jung-Il
JI
Hong
Seung-Chyul
SC
Seo
Dae Won
DW
Hong
Seung Bong
SB
D001921:Brain / Q000473:pathology*; D001932:Brain Neoplasms / Q000532:radiotherapy*; D004827:Epilepsy / Q000209:etiology / Q000601:surgery*; D005500:Follow-Up Studies; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D016634:Radiosurgery; D012640:Seizures / Q000209:etiology / Q000517:prevention & control / Q000601:surgery*; D013238:Stereotaxic Techniques