[Restless legs syndrome and psychiatric diseases].
Restless legs syndrome (RLS) is a common sleep disorder characterized by dysesthesias and paresthesias in the legs, occurring at rest, worsening at evening and night and alleviated by movements. Apart from idiopathic cases, RLS and psychiatric diseases share a common association and recent studies have shown a strong association between RLS and antidepressants. The effects of antidepressants such as selective serotonin reuptake inhibitors and venlafaxine on worsening RLS have been widely studied and their use should be avoided. The clinical spectrum of RLS and the physiopathological link with antidepressant will be discussed in this review in order to provide new preventive strategy in clinical practice to improve diagnosis, orientating therapeutic decision and evaluating efficacy of treatment.
Sforza
E
E
Laboratoire du sommeil, Département de psychiatrie, Hôpital de Belle-Idée, Chêne-Bourg. Emilia.Sforza@hcuge.ch
Cervena
K
K
D000928:Antidepressive Agents / Q000009:adverse effects*; D006801:Humans; D001523:Mental Disorders / Q000150:complications / Q000188:drug therapy; D012148:Restless Legs Syndrome / Q000139:chemically induced* / Q000150:complications
D000928:Antidepressive Agents