The fundamental contribution of Robert A. Good to the discovery of the crucial role of thymus in mammalian immunity.
Robert Alan Good was a pioneer in the field of immunodeficiency diseases. He and his colleagues defined the cellular basis and functional consequences of many of the inherited immunodeficiency diseases. His was one of the groups that discovered the pivotal role of the thymus in the immune system development and defined the separate development of the thymus-dependent and bursa-dependent lymphoid cell lineages and their responsibilities in cell-mediated and humoral immunity.
Ribatti
Domenico
D
Department of Human Anatomy and Histology, University of Bari Medical School, Bari, Italy. ribatti@anatomia.uniba.it
D000361:Agammaglobulinemia / Q000209:etiology; D000486:Allergy and Immunology / Q000266:history; D049673:History, 20th Century; D006801:Humans; D007231:Infant, Newborn; D013934:Thymectomy; D013945:Thymoma / Q000150:complications / Q000276:immunology; D013950:Thymus Gland / Q000276:immunology*; D013953:Thymus Neoplasms / Q000150:complications / Q000276:immunology; D014481:United States