title: Down syndrome with congenital hydrocephalus: case report.
abstract: Down syndrome is the most frequent genetic cause of mental retardation. Although usually presenting dysmorphic features and organ malformations, it is rarely associated with congenital hydrocephalus. The case of a male neonate whose hydrocephalus was detected since the pregnancy and was discovered to have the syndrome at birth is reported. Chromosomal analysis confirmed the genetic disorder, and hydrocephalus was treated with ventriculoperitoneal shunt because of abnormal increase of head circumference. The patient has been accompanied and his development is considered normal when compared to the expected for those affected by the syndrome.
authors.affiliation: Institute of Neurology and Neurosurgery, Rua Paissandu 1644/302, 99010-120 Passo Fundo RS, Brazil. cassianoforcelini@brturbo.com.br
authors.forename: Cassiano Mateus
authors.initials: CM
authors.lastname: Forcelini
authors.forename: Adroaldo Baseggio
authors.initials: AB
authors.lastname: Mallmann
authors.forename: Paulo Sérgio
authors.initials: PS
authors.lastname: Crusius
authors.forename: Cláudio Albano
authors.initials: CA
authors.lastname: Seibert
authors.forename: Marcelo Ughini
authors.initials: MU
authors.lastname: Crusius
authors.forename: Denise Isabel
authors.initials: DI
authors.lastname: Zandoná
authors.forename: Charles
authors.initials: C
authors.lastname: Carazzo
authors.forename: Cassiano Ughini
authors.initials: CU
authors.lastname: Crusius
authors.forename: Eduardo
authors.initials: E
authors.lastname: Goellner
authors.forename: Jean
authors.initials: J
authors.lastname: Ragnini
authors.forename: Luciano Bambini
authors.initials: LB
authors.lastname: Manzato
authors.forename: Gustavo
authors.initials: G
authors.lastname: Winkelmann
authors.forename: Aline Vieira
authors.initials: AV
authors.lastname: Lima
authors.forename: Manfred Georg
authors.initials: MG
authors.lastname: Bauermann
mesh_terms: D000328:Adult; D004314:Down Syndrome / Q000150:complications*; D005260:Female; D006801:Humans; D006849:Hydrocephalus / Q000150:complications* / Q000601:surgery; D007231:Infant, Newborn; D008297:Male; D017287:Ventriculoperitoneal Shunt