title: Ectopic parathyroid adenoma with Tc-99m MIBI washout: role of SPECT.
abstract: The authors present a case of a 71-year-old woman with clinical and biochemical features of primary hyperparathyroidism and a history of right pneumonectomy. An ultrasound scan did not demonstrate any abnormality. A planar Tc-99m methoxyisobutylisonitrile (Tc-99m MIBI) scan showed an area of minimally increased uptake within the right hemithorax. However, unlike most adenomas, this demonstrated washout similar to the thyroid at 90 minutes and 3 hours. Subsequent SPECT imaging clearly showed the lesion in the superior right hemithorax. A CT scan and angiogram confirmed the presence of this mass. After surgery, histology confirmed the diagnosis of a parathyroid adenoma. Postoperatively, the calcium and PTH levels returned to normal.
authors.affiliation: Department of Nuclear Medicine, Hammersmith Hospital, London, UK.
authors.forename: Muhammad S
authors.initials: MS
authors.lastname: Khan
authors.forename: Sameer
authors.initials: S
authors.lastname: Khan
authors.forename: Marika
authors.initials: M
authors.lastname: Vereb
authors.forename: Adil M
authors.initials: AM
authors.lastname: Al-Nahhas
authors.forename: Roberto
authors.initials: R
authors.lastname: Dina
authors.forename: J
authors.initials: J
authors.lastname: Lynn
authors.forename: W
authors.initials: W
authors.lastname: Fleming
mesh_terms: D000236:Adenoma / Q000000981:diagnostic imaging* / Q000378:metabolism / Q000601:surgery; D000368:Aged; D002828:Choristoma / Q000000981:diagnostic imaging* / Q000378:metabolism; D005260:Female; D006801:Humans; D008657:Metabolic Clearance Rate; D010280:Parathyroid Glands; D010282:Parathyroid Neoplasms / Q000000981:diagnostic imaging* / Q000378:metabolism / Q000601:surgery; D019275:Radiopharmaceuticals / Q000493:pharmacokinetics; D017256:Technetium Tc 99m Sestamibi / Q000493:pharmacokinetics; D015899:Tomography, Emission-Computed, Single-Photon / Q000379:methods
chemical_list: D019275:Radiopharmaceuticals; D017256:Technetium Tc 99m Sestamibi