Correlations between neuropsychological test results and P300 latency during silent-count and button-press tasks in post-traumatic brain injury patients.
To evaluate the correlations between memory function and intelligence and event-related potential, the P300 component for different tasks was studied for 30 post-traumatic brain injury patients (mean age 31.6 +/- 13.7 years; 23 male and 7 female). Memory function, intelligence, and depression were measured by using the Mini-Mental State Examination, the revised Wechsler Adult Intelligence Scale and the Self-Rating Depression Scale, respectively. P300 latency was measured during silent-count and button-press tests at three midline scalp (Fz, Cz, and Pz) sites for all subjects by using an auditory 'odd-ball' paradigm. Neuropsychological memory score was predicted by intelligence score, but neurophysiological P300 latency was predicted by memory score for the silent-count test and by intelligence score for the button-press test. These results show that the P300 event-related potential component is sensitive to the diverse nature of cognitive deficits in post-traumatic brain injury patients during different types of discrimination tasks. However, future research is necessary to replicate and extend these findings.
Reza
Faruque
F
Department of Rehabilitation Medicine, Hokkaido University Graduate School of Medicine, N15 W7, Sapporo 060-8638, Japan.
Ikoma
Katsunori
K
Chuma
Takayo
T
Mano
Yukio
Y
D000275:Adjustment Disorders / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology; D000328:Adult; D001930:Brain Injuries / Q000175:diagnosis / Q000503:physiopathology* / Q000523:psychology*; D002540:Cerebral Cortex / Q000293:injuries / Q000503:physiopathology*; D003072:Cognition Disorders / Q000209:etiology / Q000503:physiopathology / Q000523:psychology; D005071:Evoked Potentials / Q000502:physiology*; D006801:Humans; D007360:Intelligence / Q000502:physiology; D007361:Intelligence Tests; D008569:Memory Disorders / Q000209:etiology / Q000503:physiopathology* / Q000523:psychology*; D009483:Neuropsychological Tests; D011237:Predictive Value of Tests; D011597:Psychomotor Performance / Q000502:physiology; D011930:Reaction Time / Q000502:physiology