title: [Advances on phytoestrogen intervening breast cancer].
abstract: Phytoestrogen is the bioactive substance from plant, with structure is very simliar to that of estrogen. Phytoestrogen is mainly comprises of isoflavone, lignan and coumarin. Epidemiological restrarch shows that the increasing the uptake phytoestrogen of can reduce the morbidities of breast and other cancers. In this paper, the food source, characteristic and relevant researches both in vitro and in vivo were reviewed, and its mechanisms of intervening breast cancer were also discussed.
authors.affiliation: Anhui College of Traditional Chinese Medicine, Anhui Key Laboratory of Modernized Chinese Material Medical, Hefei 230031, China.
authors.forename: Liang-cai
authors.initials: LC
authors.lastname: Zhao
authors.forename: Li-jian
authors.initials: LJ
authors.lastname: Tang
authors.forename: Qing-lin
authors.initials: QL
authors.lastname: Li
authors.forename: Jing-gen
authors.initials: JG
authors.lastname: Liu
mesh_terms: D000818:Animals; D000975:Antioxidants / Q000494:pharmacology; D017209:Apoptosis / Q000187:drug effects*; D001943:Breast Neoplasms / Q000201:enzymology / Q000473:pathology*; D045744:Cell Line, Tumor; D003374:Coumarins / Q000494:pharmacology; D004250:DNA Topoisomerases, Type II / Q000378:metabolism; D005260:Female; D006801:Humans; D007529:Isoflavones / Q000494:pharmacology; D017705:Lignans / Q000494:pharmacology; D048789:Phytoestrogens / Q000302:isolation & purification / Q000494:pharmacology*; D010946:Plants, Medicinal / Q000737:chemistry; D011505:Protein-Tyrosine Kinases / Q000378:metabolism
chemical_list: D000975:Antioxidants; D003374:Coumarins; D007529:Isoflavones; D017705:Lignans; D048789:Phytoestrogens; D011505:Protein-Tyrosine Kinases; D004250:DNA Topoisomerases, Type II