title: Trauma-induced extracranial internal carotid artery dissection leading to multiple infarcts in a young girl.
abstract: Carotid artery dissections (CADs) represent an uncommon clinical condition that should be considered in the differential diagnosis of young individuals presenting with symptoms of stroke. The basic pathological changes in CAD include a disruption in the media or intima of arterial wall, through which the affected vasculature is predisposed to aneurysm or stenosis, and subsequent stroke. Carotid artery dissection may occur spontaneously or result from trauma, an underlying arteriopathic condition, or predisposing risk factors. The heterogeneous clinical presentations of CAD represent significant diagnostic difficulties, which often lead to delays in diagnosis and treatment. Further complicating the clinical picture is the lack of consensus regarding effective treatment modalities. Because of the often-subtle findings present in CAD, the treating physician must have a high index of suspicion to accurately diagnose and manage the condition. We report extracranial internal CAD in a 17-year-old girl leading to multiple infarcts that was successfully managed with initial antiplatelet therapy and subsequent anticoagulation.
authors.affiliation: Albert Einstein/Montefiore Medical Center, Bronx, NY, USA. s.jariwala@umdnj.edu
authors.forename: Sunit P
authors.initials: SP
authors.lastname: Jariwala
authors.forename: J Gerard
authors.initials: JG
authors.lastname: Crowley
authors.forename: Sudipta
authors.initials: S
authors.lastname: Roychowdhury
mesh_terms: D000063:Accidents, Traffic; D000293:Adolescent; D000925:Anticoagulants / Q000627:therapeutic use; D020520:Brain Infarction / Q000209:etiology / Q000534:rehabilitation; D020215:Carotid Artery, Internal, Dissection / Q000175:diagnosis* / Q000188:drug therapy* / Q000209:etiology; D002533:Cerebral Angiography; D005260:Female; D016489:Head Injuries, Closed / Q000150:complications*; D006801:Humans; D008279:Magnetic Resonance Imaging; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use; D014057:Tomography, X-Ray Computed
chemical_list: D000925:Anticoagulants; D010975:Platelet Aggregation Inhibitors