title: [Determination of metacycline in mixture sample by synchronous-derivative fluorimetry].
abstract: A new synchronous-derivative fluorimetric method for the determination of metacycline (MTC) in the presence of oxytetracycline (OTC) is proposed. The degradation products of MTC in 0.1 mol x L(-1) NaOH are strongly fluorescent. The addition of cetyltrimethylammonium bromide (CTMAB) enhances the fluorescence intensity 2-fold. The synchronous fluorescence spectra of MTC and OTC degradation products do not interfere with each other under the condition that deltalambda = 100 nm. MTC can be determined in the presence of OTC in the range of OTC+MTC ratio of 1+116-1+1. The recoveries of MTC in the mixture sample are in the range of 94%-102%.
authors.affiliation: College of Chemistry and Chemical Engineering, Inner Mongolia University, Hohhot 010021, China.
authors.forename: Gao-Wa
authors.initials: GW
authors.lastname: Aodeng
authors.forename: Ying
authors.initials: Y
authors.lastname: Zhang
authors.forename: Hai-Yan
authors.initials: HY
authors.lastname: Fan
mesh_terms: D000077286:Cetrimonium; D002593:Cetrimonium Compounds / Q000737:chemistry; D005453:Fluorescence; D006863:Hydrogen-Ion Concentration; D008690:Methacycline / Q000032:analysis* / Q000737:chemistry; D010118:Oxytetracycline / Q000737:chemistry*; D015203:Reproducibility of Results; D012972:Sodium Hydroxide / Q000737:chemistry; D013050:Spectrometry, Fluorescence / Q000379:methods*
chemical_list: D002593:Cetrimonium Compounds; D012972:Sodium Hydroxide; D008690:Methacycline; D010118:Oxytetracycline; D000077286:Cetrimonium