Model use in phylogenetics: nine key questions.
Models of character evolution underpin all phylogeny estimations, thus model adequacy remains a crucial issue for phylogenetics and its many applications. Although progress has been made in selecting appropriate models for phylogeny estimation, there is still concern about their purpose and proper use. How do we interpret models in a phylogenetic context? What are their effects on phylogeny estimation? How can we improve confidence in the models that we choose? That the phylogenetics community is asking such questions denotes an important stage in the use of explicit models. Here, we examine these and other common questions and draw conclusions about how the community is using and choosing models, and where this process will take us next.
Kelchner
Scot A
SA
Department of Biological Sciences, Idaho State University, Pocatello, ID 83209-8007, USA. kelchner@isu.edu
Thomas
Michael A
MA
D000818:Animals; D001483:Base Sequence; D005075:Biological Evolution; D023281:Genomics; D008957:Models, Genetic; D009154:Mutation; D010802:Phylogeny; D016415:Sequence Alignment