Antidepressant-like activity of the Gastrodia elata ethanol extract in mice.
The hydroalcoholic extract of Gastrodia elata was evaluated for the antidepressant-like activity by means of behavioral models that included forced swimming, tail suspending and open-field tests. According to the results, G. elata extract is effective as an antidepressant drug.
Zhou
Ben Hong
BH
The Renmin Hospital of Wuhan University, 238 Ziyang road, Wuhan City, Hubei Province, China.
Li
Xiao Jun
XJ
Liu
Min
M
Wu
Zhenhua
Z
Ming Hu
Xian
X
D000284:Administration, Oral; D000818:Animals; D000928:Antidepressive Agents / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D001522:Behavior, Animal / Q000187:drug effects*; D003863:Depression / Q000188:drug therapy; D004305:Dose-Response Relationship, Drug; D031668:Gastrodia; D008297:Male; D018782:Maze Learning; D051379:Mice; D008517:Phytotherapy; D010936:Plant Extracts / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D018517:Plant Roots; D013550:Swimming
D000928:Antidepressive Agents; D010936:Plant Extracts