title: The use of tetracaine 0.25% solution in nasal packing removal.
abstract: BACKGROUND
  The aim of this study was to evaluate efficacy of Merocel nasal package rehydration with tetracaine 0.25% solution, in reducing discomfort of nasal packing removal after septoplasty.
  
  
  METHODS
  A prospective study was conducted on patients undergoing pure septoplasty. Merocel packing was applied in each side and kept for 2 days postoperatively. Merocel was rehydrated before removal, with 4 mL of saline on one side and 4 mL of tetracaine 0.25% solution on the other side. Patients were asked to evaluate severity of pain during nasal packing removal on each side by a visual analog scale. Patients' data, pain score, and potential complications were placed in a database and statistically assessed.
  
  
  RESULTS
  Our series consisted of 141 persons. Statistical analysis showed significant lower pain score in favor of the tetracaine group. No tetracaine complications or side effects occurred.
  
  
  CONCLUSIONS
  Merocel packing rehydration with tetracaine 0.25% solution is an easy, safe, inexpensive, and effective analgesia method for nasal packing removal in septoplasty.
authors.affiliation: Department of Otolaryngology, General Hospital of Larissa, Larissa, Greece.
authors.forename: Vassilios A
authors.initials: VA
authors.lastname: Lachanas
authors.forename: George T
authors.initials: GT
authors.lastname: Karatzias
authors.forename: Vassilios G
authors.initials: VG
authors.lastname: Pinakas
authors.forename: John K
authors.initials: JK
authors.lastname: Hatziioannou
authors.forename: Vassilios G
authors.initials: VG
authors.lastname: Sandris
mesh_terms: D000293:Adolescent; D000328:Adult; D000779:Anesthetics, Local / Q000008:administration & dosage* / Q000627:therapeutic use; D005069:Evaluation Studies as Topic; D005260:Female; D005557:Formaldehyde / Q000008:administration & dosage*; D006490:Hemostatics / Q000008:administration & dosage*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009300:Nasal Septum / Q000601:surgery; D009666:Nose / Q000601:surgery; D010147:Pain Measurement; D010149:Postoperative Pain / Q000188:drug therapy*; D011142:Polyvinyl Alcohol / Q000008:administration & dosage*; D011446:Prospective Studies; D012965:Sodium Chloride / Q000008:administration & dosage / Q000627:therapeutic use; D012996:Solutions / Q000008:administration & dosage / Q000627:therapeutic use; D013630:Tampons, Surgical; D013748:Tetracaine / Q000008:administration & dosage* / Q000627:therapeutic use
chemical_list: D000779:Anesthetics, Local; D006490:Hemostatics; D012996:Solutions; D013748:Tetracaine; D005557:Formaldehyde; C027490:polyvinyl alcohol formaldehyde foam; D012965:Sodium Chloride; D011142:Polyvinyl Alcohol