A bioabsorbable microcatheter for the continuous and direct treatment of surgical sites.
A bioabsorbable microcatheter comprising of a polyglycolideco-lactide microtube and an absorbable braid is developed for the continuous delivery of therapeutic fluids directly to a surgical site. Studies conducted with tissue staining dye and radio-opaque solution using porcine models indicate that infusion of fluids in the wound site is rapid and complete. The tissue reaction to the microtube and braid is generally characterized by minimal to mild chronic inflammation or foreign body reaction that decreases in severity as the material is absorbed. The microtube is considered to be absorbed at 56 days postimplantation while the bulk of the braid is considered to be absorbed by 70 days postimplantation.
Cichocki
Frank R
FR
Ethicon Inc., A Johnson and Johnson Company, U.S. Highway 22 West, Somerville, NJ 08876, USA. fcichock@ethus.jnj.com
Barbolt
Thomas A
TA
Savidge
Sandy J
SJ
Chen
Gavin
G
Zhou
Jack
J
D020341:Absorbable Implants; D000042:Absorption; D000818:Animals; D002404:Catheterization / Q000295:instrumentation*; D011098:Polyglactin 910 / Q000737:chemistry* / Q000378:metabolism*; D013525:Surgical Instruments; D013552:Swine
D011098:Polyglactin 910