title: [Combined repair of large defect caused by radical surgery of advanced tongue cancer with rib-major pectoralis myocutaneous flap carrying costal parietal pleura].
abstract: OBJECTIVE
  To explore the clinical value and safety of using rib-major pectoralis myocutaneous flap carrying costal parietal pleura in combined repair of large soft and hard tissue defect caused by radical surgery of advanced tongue cancer.
  
  
  METHODS
  Six patients with advanced tongue carcinoma involving the floor of mouth and mandible were performed combined radical neck dissection with glossectomy and mandibulectomy, which caused large soft and hard tissue defect. Six rib-major pectoralis myocutaneous flaps carrying costal parietal pleura were transferred for immediate repair of the large defects. The rib flaps were applied for the repair of mandible, and the major pectoralis myocutaneous flaps were applied for the reconstruction of tongue and floor of mouth.
  
  
  RESULTS
  Six patients recovered well after operation. Six rib-major pectoralis myocutaneous flaps carrying costal parietal pleura survived well; the wounds of surgical incision of the oral cavity, neck, and chest healed up. The reconstructed tongue and the lower face appearance were satisfactory, the occlusion relationships were normal; the speaking as well as swallowing functions recovered.
  
  
  CONCLUSIONS
  It's safe and reliable to use rib-major pectoralis myocutaneous flap carrying costal parietal pleura to repair large soft and hard tissue defect in oral and maxillofacial region. Opening pleural cavity and harvest costal parietal pleura would not influence patients' thoracic movement and breath function and would not cause other complications. It's simple and safe for harvesting the composite flap. Carrying costal parietal pleura assures the sufficient blood supply of rib in the composite flap.
authors.affiliation: Center of Cranio-Maxillofacial Surgery, Second Affiliated Hospital, Sun Yat-sen University, Guangzhou 510120, China.
authors.forename: Chao-bin
authors.initials: CB
authors.lastname: Pan
authors.forename: Jin-song
authors.initials: JS
authors.lastname: Li
authors.forename: Hong-zhang
authors.initials: HZ
authors.lastname: Huang
authors.forename: Zhi-quan
authors.initials: ZQ
authors.lastname: Huang
authors.forename: Xiao-peng
authors.initials: XP
authors.lastname: Zhao
authors.forename: Bin
authors.initials: B
authors.lastname: Zhang
authors.forename: Zhao-hui
authors.initials: ZH
authors.lastname: Yang
authors.forename: Yong-jie
authors.initials: YJ
authors.lastname: Wang
mesh_terms: D000368:Aged; D005500:Follow-Up Studies; D005927:Glossectomy; D006801:Humans; D008297:Male; D008875:Middle Aged; D009060:Mouth Floor / Q000601:surgery; D037981:Neck Dissection; D010369:Pectoralis Muscles / Q000637:transplantation*; D019651:Plastic Surgery Procedures / Q000379:methods*; D013524:Surgical Flaps; D014062:Tongue Neoplasms / Q000473:pathology / Q000601:surgery*; D014182:Transplantation, Autologous; D016896:Treatment Outcome