[Hashimoto's encephalopathy].
Hashimoto's encephalopathy (HE) is not an often complication of autoimmune thyroiditis, usually at the time the patient is already euthyroid i.e. with normal TSH-value but positive antibodies to thyroid hormones. Signs and symptoms are acute or sub-acute, such as cerebrovascular accident, epileptic seizures generalised, myoclonic or partial, cognitive function disorder with dementia and psychical disorders. Pathological findings, even non-specifical, can be found in cerebrospinal fluid, by electroencefalography (EEG) or by brain scan with magnetic resonance (MR). Pathogenesy of the disease is unclear; however, corticoid treatment is usually succesful. Therefore, HE should be taken into consideration after elimination of all other causes of encephalopathy, with thyroiditis in family history in particular.
Vondrová
H
H
Neurologická klinika IPVZ a Fakultní Thomayerovy nemocnice, Praha. vondrova@ftn.cz
D001927:Brain Diseases / Q000175:diagnosis / Q000209:etiology* / Q000503:physiopathology; D050031:Hashimoto Disease / Q000150:complications*; D006801:Humans