Proposal for diagnostic criteria of tropical spastic paraparesis/HTLV-I-associated myelopathy (TSP/HAM).
After the first description of TSP/HAM in 1985 and the elaboration of WHO's diagnostic criteria in 1988, the experience of the professionals in this field has increased so that a critical reappraisal of these diagnostic guidelines was considered timely. Brazilian neurologists and observers from other countries met recently to discuss and propose a modified model for diagnosing TSP/HAM with levels of ascertainment as definite, probable, and possible, according to myelopathic symptoms, serological findings, and/or detection of HTLV-I DNA and exclusion of other disorders.
De Castro-Costa
Carlos M
CM
Departamento de Fisiologia e Farmacologia, Universidade Federal do Ceará, Rodolfo Teófilo, 60430-270, Fortaleza-CE, Brazil.
Araújo
Abelardo Q C
AQ
Barreto
Márcio M
MM
Takayanagui
Osvaldo M
OM
Sohler
Marzia P
MP
da Silva
Eduardo L M
EL
de Paula
Sônia M B
SM
Ishak
Ricardo
R
Ribas
João G R
JG
Rovirosa
Luis C
LC
Carton
Herwig
H
Gotuzzo
Eduardo
E
Hall
William W
WW
Montano
Silvia
S
Murphy
Edward L
EL
Oger
Joel
J
Remondegui
Carlos
C
Taylor
Graham P
GP
D000328:Adult; D015480:Deltaretrovirus Antibodies / Q000276:immunology; D005260:Female; D006801:Humans; D015493:Paraparesis, Tropical Spastic / Q000175:diagnosis* / Q000276:immunology
D015480:Deltaretrovirus Antibodies