title: Repeated resection for intra-abdominal and retroperitoneal liposarcomas: long-term experience in a single cancer center in Japan.
abstract: Intra-abdominal or retroperitoneal liposarcomas are huge, and local recurrence is a common event. There is still no consensus concerning debulking or repeated resection. Twelve patients who had surgery for intra-abdominal or retroperitoneal liposarcomas at the Cancer Institute Hospital (Tokyo, Japan) during 1981-2002 were enrolled. Eight patients underwent complete resection, for a resectability rate of 67%. Combined resection of adjacent organs was necessary to obtain clear margins in 10 of the 12 patients (83%). A patient who underwent R2 resection survived 13.2 years in a dormant state without tumor regrowth. Resection of second (five patients), third (three patients), or seventh (one patient) for local recurrence or regrowth tumors was successfully performed. A patient survived 21.5 years after four R0 resections and three R2 resections. Our experience suggests that both near-total and repeated resection might improve survival benefit.
authors.affiliation: Department of Gastrointestinal Surgery, Cancer Institute Hospital, 3-10-6 Ariake, Kotoku, Tokyo, 135-8550, Japan. takahiro.sato@jfcr.or.jp
authors.forename: Takahiro
authors.initials: T
authors.lastname: Sato
authors.forename: Toshiharu
authors.initials: T
authors.lastname: Yamaguchi
authors.forename: Kaoru
authors.initials: K
authors.lastname: Azekura
authors.forename: Masashi
authors.initials: M
authors.lastname: Ueno
authors.forename: Shigekazu
authors.initials: S
authors.lastname: Ohyama
authors.forename: Masatoshi
authors.initials: M
authors.lastname: Ohya
authors.forename: Junji
authors.initials: J
authors.lastname: Yamamoto
authors.forename: Tetsuichiro
authors.initials: T
authors.lastname: Muto
authors.forename: Yuichi
authors.initials: Y
authors.lastname: Ishikawa
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Kanda
mesh_terms: D000008:Abdominal Neoplasms / Q000601:surgery*; D000328:Adult; D000368:Aged; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007564:Japan; D008080:Liposarcoma / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000601:surgery*; D012186:Retroperitoneal Neoplasms / Q000601:surgery*; D013997:Time Factors