Disappearance of frontal N30 component of median nerve stimulated SSEPs in two young children with abnormal striatal lesions.
Median nerve stimulated short-latency somatosensory evoked potentials (MN-SSEPs) were performed in two young children with extrapyramidal symptoms. Brain MRI showed bilaterally symmetric striatal lesions in both cases. The subcortical components (N9, N11, N13, N18, P11, and P13) and the parietal component (N20) were normally detected, whereas the frontal component (N30) was not detected bilaterally in either case. In conclusion, our findings suggest that frontal N30 disappearance could be observed since as early as young childhood and it may pathophysiologically reflect severe dysfunction in the extrapyramidal system.
Kato
Yosuke
Y
Department of Pathobiological Science and Technology, School of Health Science, Faculty of Medicine, Tottori University, 86 Nishi-cho, Yonago 683-8503, Japan. ykato@grape.med.tottori-u.ac.jp
Fukuda
Chisako
C
Maegaki
Yoshihiro
Y
Inoue
Takehiko
T
Hiraiwa
Rika
R
Hiraiwa
Hisayuki
H
Ohno
Kousaku
K
Tomita
Yutaka
Y
D001930:Brain Injuries / Q000473:pathology* / Q000503:physiopathology*; D002648:Child; D003342:Corpus Striatum / Q000473:pathology*; D004558:Electric Stimulation / Q000379:methods; D004569:Electroencephalography / Q000379:methods; D005073:Evoked Potentials, Somatosensory / Q000502:physiology*; D005625:Frontal Lobe / Q000503:physiopathology*; D006801:Humans; D007223:Infant; D008297:Male; D008475:Median Nerve / Q000528:radiation effects; D011930:Reaction Time / Q000502:physiology* / Q000528:radiation effects