title: Chiral bicyclic guanidine-catalyzed enantioselective reactions of anthrones.
abstract: Chiral bicyclic guanidine 1 was found to be an excellent catalyst for reactions between anthrones and various dienophiles. The catalyst can tolerate a range of substituents and substitution patterns, making several anthrone derivatives suitable for this reaction. Both Diels-Alder and Michael adducts were obtained in excellent yields, high regioselectivities, and high enantioselectivities. This is the first case of a highly enantioselective base-catalyzed anthrone Diels-Alder reaction.
authors.affiliation: Department of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore 117543.
authors.forename: Juan
authors.initials: J
authors.lastname: Shen
authors.forename: Thanh Truc
authors.initials: TT
authors.lastname: Nguyen
authors.forename: Yong-Peng
authors.initials: YP
authors.lastname: Goh
authors.forename: Weiping
authors.initials: W
authors.lastname: Ye
authors.forename: Xiao
authors.initials: X
authors.lastname: Fu
authors.forename: Junye
authors.initials: J
authors.lastname: Xu
authors.forename: Choon-Hong
authors.initials: CH
authors.lastname: Tan