title: Selective effects of external noise on Ca2+ signal in mesoscopic scale biochemical cell systems.
abstract: We have investigated how the external noise would influence the intracellular calcium signaling processes due to the existence of internal noise in small systems. Using chemical Langevin equations, we demonstrate numerically that the behavior of 'system size bi-resonance' induced by internal noise will change with the external noise intensity in different regions, indicating the occurrence of selective effects of external noise. Meanwhile, cell system may also automatically select an optimal cell size to obtain the best performance in the presence of external noise. These results may imply that such selective-effect phenomenon should have some inherent relevance with the distinct deterministic bifurcation features of the system.
authors.affiliation: College of Physics and Electronic Information, Anhui Normal University, Wuhu, Anhui, 241000, PR China.
authors.forename: Hanshuang
authors.initials: H
authors.lastname: Chen
authors.forename: Jiqian
authors.initials: J
authors.lastname: Zhang
authors.forename: Jianqing
authors.initials: J
authors.lastname: Liu
mesh_terms: D000818:Animals; D020013:Calcium Signaling; D048429:Cell Size; D002478:Cells, Cultured; D022781:Hepatocytes / Q000166:cytology*; D008956:Models, Chemical; D009622:Noise; D051381:Rats; D013269:Stochastic Processes