title: Measurement of transcallosal inhibition in traumatic brain injury by transcranial magnetic stimulation.
abstract: OBJECTIVE
  To study whether transcallosal inhibition (TCI) can evaluate the severity of traumatic brain injury (TBI).
  
  
  METHODS
  Case-control study.
  
  
  METHODS
  Twenty patients with a chronic TBI and 20 control subjects were studied. The following transcranial magnetic stimulation parameters were checked; resting motor threshold, central motor latency times, onset latency of TCI, duration of TCI, transcallosal conduction times and amount of TCI. The severity of TBI was evaluated using the Glasgow Coma Scale (GCS).
  
  
  RESULTS
  The amount of TCI was significantly lower in the patients than the control subjects (p < 0.001). The amount of TCI was highly correlated with the GCS (r = 0.787, p < 0.001).
  
  
  CONCLUSIONS
  An assessment of TCI was found to be a more sensitive and useful method for an evaluation of the severity of TBI.
authors.affiliation: Department of Rehabilitation Medicine, Hokkaido University Graduate School of Medicine, Sapporo, Japan. naoyuki@med.hokudai.ac.jp
authors.forename: Naoyuki
authors.initials: N
authors.lastname: Takeuchi
authors.forename: Katsunori
authors.initials: K
authors.lastname: Ikoma
authors.forename: Takayo
authors.initials: T
authors.lastname: Chuma
authors.forename: Yuichiro
authors.initials: Y
authors.lastname: Matsuo
mesh_terms: D000328:Adult; D001930:Brain Injuries / Q000503:physiopathology*; D016022:Case-Control Studies; D002908:Chronic Disease; D003337:Corpus Callosum / Q000502:physiology*; D004576:Electromyography; D019054:Evoked Potentials, Motor / Q000502:physiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011930:Reaction Time / Q000502:physiology; D050781:Transcranial Magnetic Stimulation