Determination of polybrominated diphenyl ethers in domestic dust by microwave-assisted solvent extraction and gas chromatography-tandem mass spectrometry.
In this paper, a rapid and simple method for the analysis of polybrominated diphenyl ethers (PBDEs) in house dust samples based on microwave-assisted solvent extraction (MASE) and gas chromatography-tandem mass spectrometry (GC-MS/MS) is presented. Extraction conditions were optimized using a multifactorial experimental design approach. The use of an aqueous NaOH phase in combination with a non-polar organic phase (hexane) to extract the target analytes from dust allowed an efficient extraction and reduced chromatographic background. The final hexane extracts could be analyzed after a simple one-step cleanup procedure using Florisil. The validation of the method was performed in terms of accuracy, linearity, and repeatability. The limits of detection (LODs) ranged from 0.29 to 0.55 ng/g for all compounds. The target PBDEs were found in several real dust samples collected in urban and rural houses of Northwestern Spain.
Regueiro
Jorge
J
Departamento de Química Analítica, Nutrición y Bromatología, Instituto de Investigación y Análisis Alimentario, Universidad de Santiago de Compostela, Santiago de Compostela 15782, Spain.
Llompart
Maria
M
García-Jares
Carmen
C
Cela
Rafael
R
D053000:Analytic Sample Preparation Methods; D004391:Dust / Q000032:analysis*; D004785:Environmental Pollutants / Q000032:analysis*; D008401:Gas Chromatography-Mass Spectrometry / Q000379:methods*; D006842:Hydrocarbons, Brominated / Q000032:analysis*; D006863:Hydrogen-Ion Concentration; D008872:Microwaves; D010647:Phenyl Ethers / Q000032:analysis*; D015203:Reproducibility of Results; D012997:Solvents; D053719:Tandem Mass Spectrometry / Q000379:methods*
D004391:Dust; D004785:Environmental Pollutants; D006842:Hydrocarbons, Brominated; D010647:Phenyl Ethers; D012997:Solvents