title: Trisubstituted aziridine ring-opening by phenol derivatives: stereo- and regioselective formation of chiral tertiary alkyl-aryl ethers.
abstract: An unprecedented stereo- and regioselective trisubstituted aziridine ring-opening by phenol derivatives was discovered. The reaction features very mild reaction conditions and broad functional group compatibility, which provides a good method for the stereoselective formation of tertiary alkyl-aryl ethers in highly functionalized systems. [reaction: see text]
authors.affiliation: Department of Chemistry, University of Pennsylvania, 231 South 34th Street, Philadelphia, PA 19104, USA.
authors.forename: Pixu
authors.initials: P
authors.lastname: Li
authors.forename: Erin M
authors.initials: EM
authors.lastname: Forbeck
authors.forename: Cory D
authors.initials: CD
authors.lastname: Evans
authors.forename: Madeleine M
authors.initials: MM
authors.lastname: Joullié
mesh_terms: D001388:Aziridines / Q000737:chemistry*; D002384:Catalysis; D004987:Ethers / Q000138:chemical synthesis*; D015394:Molecular Structure; D010636:Phenols / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D001388:Aziridines; D004987:Ethers; D010636:Phenols