title: Studying the evolution and the magnetic resonance findings of reversible posterior leukoencephalopathy in children.
abstract: OBJECTIVE
  To describe the evolution and the magnetic resonance imaging (MRI) findings of the reversible posterior leukoencephalopathy (RLPS) in children.
  
  
  METHODS
  Nine children with neurologic symptoms and sudden increase of the arterial pressure were studied by brain MRI.
  
  
  RESULTS
  All children evaluated had lesions seen on FLAIR-weighted images of the parietal-occipital regions. Other regions were also involved. Four patients presented restriction on diffusion-weighted images and only two with reduction of the apparent diffusion coefficient (ADC), which evolved with neurologic sequels and persistence of the lesions on the control examination. The other patients had complete regression of the lesions after therapy.
  
  
  CONCLUSIONS
  MRI is important to suggest the diagnosis of RPLS in patients with arterial hypertension and unspecific neurologic symptoms. Moreover, the outcome is not favorable all the time and the association of D-WI with ADC can be an instrument capable of predicting irreversible lesions.
authors.affiliation: Department of Radiology, Faculdade de Medicina Estadual de Rio Preto, Hospital de Base de São Jose do Rio Preto SP, Rua Brigadeiro Faria Lima 5544, 15090-000 São Jose do Rio Preto SP, Brazil. jrl.ferraz@terra.com.br
authors.forename: José Roberto
authors.initials: JR
authors.lastname: Ferraz-Filho
authors.forename: José Alves
authors.initials: JA
authors.lastname: Rocha-Filho
authors.forename: Tatiana Fantin
authors.initials: TF
authors.lastname: Bichuette
authors.forename: Regina Celia Ajeje P
authors.initials: RC
authors.lastname: de Albuquerque
authors.forename: Rafael Angelo
authors.initials: RA
authors.lastname: Sanchez
authors.forename: Antonio Soares
authors.initials: AS
authors.lastname: Souza
mesh_terms: D000293:Adolescent; D001927:Brain Diseases / Q000175:diagnosis* / Q000473:pathology; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D006973:Hypertension / Q000175:diagnosis* / Q000473:pathology; D008279:Magnetic Resonance Imaging; D008297:Male; D011446:Prospective Studies; D013577:Syndrome