title: The incidence of end-stage renal disease in India: a population-based study.
abstract: Chronic kidney disease (CKD) and end-stage renal disease (ESRD) are emerging public health problems in developing countries, and need changes in health-care policy. ESRD incidence data are not available from large parts of the developing world including South Asia. We report the ESRD incidence in a large urban population in India. ESRD incidence was estimated for four consecutive calendar years (2002-2005) among 572 029 subjects residing in 36 of the 56 wards of the city of Bhopal. These subjects are beneficiaries of free health care in a hospital established after the 1984 Union Carbide Industrial Accident. Crude and age-adjusted incidence rates were calculated. A total of 346 new ESRD patients were diagnosed during the study period; 86 in 2002, 82 in 2003, 85 in 2004, and 93 in 2005. Average crude and age-adjusted incidence rates were 151 and 232 per million population, respectively. The mean age was 47 years, and 58% were males. Diabetic nephropathy was the commonest (44%) cause of ESRD. This study provides the first population-based ESRD incidence data from India and reveals it to be higher than previously estimated. Diabetic nephropathy is the leading cause of ESRD. Changes are required in health-care policy for optimal care of CKD patients and efficient resource utilization for management of those with ESRD.
authors.affiliation: Department of Nephrology, Bhopal Memorial Hospital and Research Centre, Bhopal, Madhya Pradesh, India.
authors.forename: G K
authors.initials: GK
authors.lastname: Modi
authors.forename: V
authors.initials: V
authors.lastname: Jha
mesh_terms: D000328:Adult; D017677:Age Distribution; D003928:Diabetic Nephropathies / Q000453:epidemiology; D005260:Female; D006291:Health Policy; D006801:Humans; D015994:Incidence; D007194:India / Q000453:epidemiology; D007676:Kidney Failure, Chronic / Q000453:epidemiology*; D008297:Male; D008875:Middle Aged; D014505:Urban Population / Q000706:statistics & numerical data*