[Study on the TLC-SERS of sulfamethoxazole].
The spectra of sulfamethoxazole, the efficient ingredient of sulfanilamide-like medicine, were investigated by combining the TLC and FT-Raman spectroscopy using the surface enhanced Raman spectroscopy technique. The result indicatesthat the main vibrant characteristic spectral band can be obtained by TLC in a samples of just about 1 microg. The difference between the compound sulfamethoxazole and the corresponding spectra picture is analyzed. The analysis shows that the method of combining TLC and FT-Raman spectroscopy by the SERS is practical and advantageous in the highly sensitive measurement of the chemical ingredient in medicine.
Zhang
Jin-Zhi
JZ
Department of Physics, North China University of Technology, Beijing 100041, China.
Wang
Yuan
Y
Chen
Xiang-Ming
XM
D002855:Chromatography, Thin Layer / Q000379:methods*; D005782:Gels; D015394:Molecular Structure; D015203:Reproducibility of Results; D012822:Silicon Dioxide / Q000737:chemistry; D013059:Spectrum Analysis, Raman / Q000379:methods*; D013420:Sulfamethoxazole / Q000032:analysis* / Q000737:chemistry
D005782:Gels; D012822:Silicon Dioxide; D013420:Sulfamethoxazole