title: Regio- and diastereocontrolled C-H insertion of chiral gamma- and delta-lactam diazoacetates. Application to the asymmetric synthesis of (8S,8aS)-8-hydroxyindolizidine.
abstract: gamma- and delta-Lactam diazoacetates undergo efficient intramolecular C-H insertion catalyzed by Rh2(MPPIM)4 with excellent regioselectivity and cis-diastereoselectivity to provide synthetically useful bicyclic lactam lactones.
authors.affiliation: Department of Chemistry and Biochemistry, University of Regina, Regina, Saskatchewan S4S 0A2, Canada.
authors.forename: Gao-Jun
authors.initials: GJ
authors.lastname: Fan
authors.forename: Zhongyi
authors.initials: Z
authors.lastname: Wang
authors.forename: Andrew G H
authors.initials: AG
authors.lastname: Wee