title: Molecular typing and anti-microbial susceptibility of clinical isolates of Streptococcus equi ssp. zooepidemicus from equine bacterial endometritis.
abstract: The anti-microbial susceptibility and genetic diversity of 65 strains of Streptococcus equi ssp. zooepidemicus (Sez) isolated from mares presenting clinical signs of endometritis was determined by disk agar diffusion and pulsed field gel electrophoresis (PFGE) methods, respectively. Overall, Sez isolates were susceptible to beta-lactams, enrofloxacin, trimethoprim-sulfamethoxazole and gentamicin. These anti-microbials could be recommended as empiric anti-microbial therapy in cases of endometritis caused by Sez. Pulsed field gel electrophoresis typing revealed a great genetic diversity (56 different PFGE macrorestriction profiles) and a low level of genetic relatedness amongst the isolates.
authors.affiliation: Departamento de Sanidad Animal, Facultad de Veterinaria, Campus Universitario de Rabanales, 14071 Córdoba, Spain. sa1lumoi@uco.es
authors.forename: I
authors.initials: I
authors.lastname: Luque
authors.forename: J F
authors.initials: JF
authors.lastname: Fernández-Garayzábal
authors.forename: V
authors.initials: V
authors.lastname: Blume
authors.forename: A
authors.initials: A
authors.lastname: Maldonado
authors.forename: R
authors.initials: R
authors.lastname: Astorga
authors.forename: C
authors.initials: C
authors.lastname: Tarradas
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D016000:Cluster Analysis; D004269:DNA, Bacterial / Q000032:analysis*; D024881:Drug Resistance, Bacterial; D016521:Electrophoresis, Gel, Pulsed-Field / Q000379:methods / Q000662:veterinary; D004716:Endometritis / Q000188:drug therapy / Q000382:microbiology / Q000662:veterinary*; D005260:Female; D014644:Genetic Variation; D006734:Horse Diseases / Q000188:drug therapy / Q000382:microbiology*; D006736:Horses; D008826:Microbial Sensitivity Tests / Q000662:veterinary; D010802:Phylogeny; D013290:Streptococcal Infections / Q000188:drug therapy / Q000382:microbiology / Q000662:veterinary*; D018502:Streptococcus equi / Q000145:classification / Q000187:drug effects / Q000235:genetics
chemical_list: D000900:Anti-Bacterial Agents; D004269:DNA, Bacterial