title: [Efficacy in endoscopic treatment of secondary vesicoureteral reflux with polydimethylsiloxane].
abstract: OBJECTIVE
  To value the efficacy in endoscopic treatment of the vesicoureteral reflux (VUR).
  
  
  METHODS
  We have realized a prospective study in patients with RVU treated with endoscopic polydimethylsiloxane, from January 1999 until December 2001, analyzing the results after an average pursuit of 30 months. We included 144 patients, 92 girls and 52 children, with 213 VUR (124 primary ones and 89 of secondary etiology). The initial efficacy of the treatment was defined as the finished absence of RVU in the isotopic cystography, realized three months after the puncture.
  
  
  RESULTS
  The global efficacy of the endoscopic treatment in secondary etiology reflux was lower than the reached one in the treatment of the primary RVU (77.7% against 86.2%) but the differences did not reach statistical significance (p=0,226). We do not also find significant differences on having compared the injected volume and the valuation of resolution of the ebb between the different causes of secondary RVU (p=0.361). We found recurrence in patients with RVU due to lower urinary tract dysfunction (4.34%).
  
  
  CONCLUSIONS
  Endoscopic treatment of the secondary VUR is a minimally invasive skill, presents scarce morbidity and it is effective in chosen patients. The risk of a long term recurrence is grater in VUR secondary to functional alterations (neurogenic bladder and functional instability), for what, pursuit has to be established according to the base pathology.
authors.affiliation: Servicio de Urología Infantil, Hospital Universitario La Fe, Valencia. serrano_agu@gva.es
authors.forename: A
authors.initials: A
authors.lastname: Serrano Durbá
authors.forename: L
authors.initials: L
authors.lastname: Gómez Pérez
authors.forename: J F
authors.initials: JF
authors.lastname: Estornell Moragues
authors.forename: C
authors.initials: C
authors.lastname: Domínguez Hinarejos
authors.forename: M
authors.initials: M
authors.lastname: Martínez Verduch
authors.forename: F
authors.initials: F
authors.lastname: García Ibarra
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D003558:Cystoscopy; D004129:Dimethylpolysiloxanes / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D011446:Prospective Studies; D012828:Silicones / Q000008:administration & dosage*; D018666:Ureteroscopy; D014718:Vesico-Ureteral Reflux / Q000209:etiology / Q000628:therapy*
chemical_list: D004129:Dimethylpolysiloxanes; D012828:Silicones; C013830:baysilon