title: Optical coherence tomography evaluation of idiopathic macular hole treatment by gas-assisted posterior vitreous detachment.
abstract: OBJECTIVE
  To report a series of patients with Stage II macular hole (MH) treated by gas-assisted posterior vitreous detachment (GAPVD).
  
  
  METHODS
  Interventional case series.
  
  
  METHODS
  Six patients (six eyes) with Stage II MH were submitted to a 0.4 ml perfluoropropane (C(3)F(8)) intravitreal injection. Comprehensive ophthalmic examination including best-corrected visual acuity, fundus photography, and optical coherence tomography (OCT) was performed at baseline and one, three, and six months after the procedure.
  
  
  RESULTS
  Preoperative OCT revealed Stage II MH in all cases. In five cases, improvement in visual acuity and closure of the macular hole on OCT was observed at one, three, and six months after GAPVD. In one case, although vitreofoveal traction was released, MH closure was not achieved; a full-thickness retinal defect persisted and final visual acuity was 20/100.
  
  
  CONCLUSIONS
  GAPVD may be a viable alternative treatment for Stage II MH.
authors.affiliation: Department of Ophthalmology, Ribeirão Preto School of Medicine, University of São Paulo, Ribeirão Preto, São Paulo, Brazil. rjorge@fmrp.usp.br
authors.forename: Rodrigo
authors.initials: R
authors.lastname: Jorge
authors.forename: Rogério A
authors.initials: RA
authors.lastname: Costa
authors.forename: José A
authors.initials: JA
authors.lastname: Cardillo
authors.forename: Fausto
authors.initials: F
authors.lastname: Uno
authors.forename: Pedro P
authors.initials: PP
authors.lastname: Bonomo
authors.forename: Michel E
authors.initials: ME
authors.lastname: Farah
mesh_terms: D005466:Fluorocarbons / Q000627:therapeutic use*; D006801:Humans; D016684:Prone Position; D012167:Retinal Perforations / Q000175:diagnosis* / Q000188:drug therapy*; D041623:Tomography, Optical Coherence; D014792:Visual Acuity; D014822:Vitreous Body / Q000187:drug effects*; D020255:Vitreous Detachment / Q000209:etiology*
chemical_list: D005466:Fluorocarbons; C042852:perflutren