title: [Development of audiogenic kindling during the gestation period].
abstract: Some peculiarities of audiogenic kindling were studied in rats with genetically determined epileptic seizures during gestation period. In the period of gestation the development of audiogenic kindling in response to repetitive acoustic stimulation is markedly reduced. This indicates the strengthening of inhibitory processes in the brain. It is supposed that in the period of gestation in rats with genetically determined audiogenic seizures excess of sexual hormones and enhancement of GABA-ergic transmission causes marked reduction of development of audiogenic kindling.
authors.forename: N T
authors.initials: NT
authors.lastname: Samseishvili
authors.forename: I G
authors.initials: IG
authors.lastname: Bilanishvili
authors.forename: T R
authors.initials: TR
authors.lastname: Chachua
authors.forename: B D
authors.initials: BD
authors.lastname: Tkeshelashvili
authors.forename: Z I
authors.initials: ZI
authors.lastname: nanobashvili
mesh_terms: D000161:Acoustic Stimulation / Q000379:methods; D000818:Animals; D047108:Embryonic Development / Q000502:physiology*; D020195:Epilepsy, Reflex / Q000503:physiopathology*; D005260:Female; D007696:Kindling, Neurologic / Q000502:physiology*; D051381:Rats