title: Signal transduction. Prelude to an anniversary for the RAS oncogene.
authors.affiliation: Signal Transduction Laboratory, Cancer Research UK London Research Institute, London WC2A 3PX, UK. julian.downward@cancer.org.uk
authors.forename: Julian
authors.initials: J
authors.lastname: Downward
mesh_terms: D049109:Cell Proliferation; D002471:Cell Transformation, Neoplastic; D011905:Genes, ras; D018095:Germ-Line Mutation; D006801:Humans; D007425:Intracellular Membranes / Q000378:metabolism; D047908:Intracellular Signaling Peptides and Proteins / Q000378:metabolism; D020930:MAP Kinase Kinase Kinases / Q000378:metabolism; D021962:Membrane Microdomains / Q000378:metabolism; D009154:Mutation; D009369:Neoplasms / Q000188:drug therapy / Q000235:genetics* / Q000378:metabolism; D019869:Phosphatidylinositol 3-Kinases / Q000378:metabolism; D048493:Proto-Oncogene Proteins B-raf / Q000378:metabolism; D015398:Signal Transduction; D018631:ras Proteins / Q000235:genetics / Q000378:metabolism*
chemical_list: D047908:Intracellular Signaling Peptides and Proteins; D019869:Phosphatidylinositol 3-Kinases; D048493:Proto-Oncogene Proteins B-raf; D020930:MAP Kinase Kinase Kinases; D018631:ras Proteins