title: Primary hyperaldosteronism in a dog with concurrent lymphoma.
abstract: An 11-year-old, male castrated English springer spaniel was presented for muscle weakness, lethargy and anorexia while undergoing treatment of Stage IV lymphoma. Persistent hypokalemia prompted multiple diagnostic tests. Serum aldosterone levels, surgical exploration and histopathology confirmed primary hyperaldosteronism. Hyperaldosteronism is a rarely reported endocrinopathy in the dog. This report describes a case in which immunohistochemistry was utilized to confirm the diagnosis of an aldosterone-secreting tumour.
authors.affiliation: Department of Veterinary Medicine and Surgery, University of Missouri, Columbia, MO, USA. johnkim@missouri.edu
authors.forename: K D
authors.initials: KD
authors.lastname: Johnson
authors.forename: C J
authors.initials: CJ
authors.lastname: Henry
authors.forename: D L
authors.initials: DL
authors.lastname: McCaw
authors.forename: S E
authors.initials: SE
authors.lastname: Turnquist
authors.forename: M R
authors.initials: MR
authors.lastname: Stoll
authors.forename: M
authors.initials: M
authors.lastname: Kiupel
authors.forename: P J
authors.initials: PJ
authors.lastname: Bondy
mesh_terms: D000818:Animals; D003937:Diagnosis, Differential; D004283:Dog Diseases / Q000175:diagnosis / Q000473:pathology*; D004285:Dogs; D017809:Fatal Outcome; D006929:Hyperaldosteronism / Q000175:diagnosis / Q000473:pathology / Q000662:veterinary*; D007150:Immunohistochemistry / Q000662:veterinary; D008223:Lymphoma / Q000175:diagnosis / Q000473:pathology / Q000662:veterinary*; D008297:Male