Hepatitis C virus genotype 4 in Ugandan children and their mothers.
In Kampala, Uganda, in 2001, hepatitis C virus antibodies were found in 27 (4%) of 603 children and in 62 (12%) of 525 of their mothers. However, only approximately 10% of positive results were confirmed by reverse transcription-PCR, which suggests frequent false-positive results or viral clearance. All sequenced types were genotype 4.
Biggar
Robert J
RJ
Viral Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland 20852, USA. biggarb@mail.nih.gov
Ortiz-Conde
Betty A
BA
Bagni
Rachel K
RK
Bakaki
Paul M
PM
Wang
Cheng-Dian
CD
Engels
Eric A
EA
Mbulaiteye
Sam M
SM
Ndugwa
Christopher M
CM
D000293:Adolescent; D000328:Adult; D000755:Anemia, Sickle Cell / Q000150:complications; D002648:Child; D002675:Child, Preschool; D005260:Female; D005838:Genotype; D016174:Hepacivirus / Q000145:classification* / Q000235:genetics* / Q000302:isolation & purification; D006526:Hepatitis C / Q000453:epidemiology* / Q000821:virology*; D018937:Hepatitis C Antibodies / Q000097:blood; D006801:Humans; D007223:Infant; D008297:Male; D008969:Molecular Sequence Data; D009035:Mothers; D010802:Phylogeny; D012367:RNA, Viral / Q000032:analysis / Q000097:blood; D020133:Reverse Transcriptase Polymerase Chain Reaction; D017422:Sequence Analysis, DNA; D065227:Transfusion Reaction; D014454:Uganda / Q000453:epidemiology
D018937:Hepatitis C Antibodies; D012367:RNA, Viral