title: [Radioactive seed implantation in treatment of oral and maxillofacial malignancy].
abstract: OBJECTIVE
  To treat oral and maxillofacial malignant tumors with radioactive seed implantation and observe the therapeutic results and side effects.
  
  
  METHODS
  Thirty-six patients with oral and maxillofacial malignancy were treated by radioactive seeds implanting (operation and seed implantation or seed implantation only). The treatment plans were designed before implanting by treatment plan system (TPS). All patients were followed up for 6 - 36 months with an average of 14 months and the results evaluated.
  
  
  RESULTS
  In 3 patients treated only by seed implantation, the tumor size reduced obviously and the symptoms alleviated in 2 patients with advanced disease, and the tumor got complete remission in one patient with tongue cancer. In the other 33 patients who were implanted after operation, no recurrence was seen in the target area, but recurrence or lymph node metastasis was found outside the target area in 3 patients. There were no unusual complaint and external radiotherapeutic side effects except for skin hyperemia occurred in 8 patients.
  
  
  CONCLUSIONS
  Radioactive seed implantation is very effective for preventing recurrence and metastasis of oral and maxillofacial malignancy.
authors.affiliation: Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology, Beijing 100081, China.
authors.forename: Jian-guo
authors.initials: JG
authors.lastname: Zhang
authors.forename: Jie
authors.initials: J
authors.lastname: Zhang
authors.forename: Tie-li
authors.initials: TL
authors.lastname: Song
authors.forename: Zhi-gang
authors.initials: ZG
authors.lastname: Cai
authors.forename: Wen-jing
authors.initials: WJ
authors.lastname: Sheng
authors.forename: Guang-yan
authors.initials: GY
authors.lastname: Yu
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001918:Brachytherapy / Q000379:methods*; D005153:Facial Neoplasms / Q000532:radiotherapy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007573:Jaw Neoplasms / Q000532:radiotherapy; D008297:Male; D008875:Middle Aged; D009062:Mouth Neoplasms / Q000532:radiotherapy*; D016896:Treatment Outcome; D055815:Young Adult