[Studies on chemical constituents in root tuber of Cynanchum auriculatum].
OBJECTIVE
To study chemical constituents from Cynanchum auriculatum.


METHODS
The chemical components were isolated and purified by silca gel, sephedex-LH-20 and ODS column chromatography. The chemical structures were elucidated on the basis of physicochemical properties and spectral data.


RESULTS
Thirteen compounds were isolated and identified as: caudatin (1), metaplexigenin (2), cynauricuoside A (3), succinic acid (4), azelaic acid (5), wilforibiose (6), sucrose (7), 1-O-hexadecanolenin (8), beta-amyrin acetate (9), cynanchone A (10), acetylquinol (11), beta-sitosterol (12), daucosterol (13).


CONCLUSIONS
Compounds 4-9 were obtained from this plant for the first time.
Zhang
Jian-feng
JF
Department of Pharmacy, China Pharmaceutical University, Nanjing 210028, China.
Li
You-bin
YB
Li
Cheng-lu
CL
Jiang
Jian-qin
JQ
D031105:Cynanchum / Q000737:chemistry*; D003998:Dicarboxylic Acids / Q000737:chemistry / Q000302:isolation & purification*; D009828:Oleanolic Acid / Q000031:analogs & derivatives* / Q000737:chemistry / Q000302:isolation & purification; D035281:Plant Tubers / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D019802:Succinic Acid / Q000737:chemistry / Q000302:isolation & purification*
D003998:Dicarboxylic Acids; D009828:Oleanolic Acid; D019802:Succinic Acid; C000265:beta-amyrin acetate; C010038:azelaic acid