Regioselective Heck arylation of unsaturated alcohols by palladium catalysis in ionic liquid.
In contrast to almost all of the known examples of Heck arylation of unsaturated alcohols, which yield predominately beta-arylated products, arylation under the Pd-DPPP catalysis in ionic liquid leads preferentially to aryl substitution at the alpha carbon, providing an easy pathway to this valuable class of olefins.
Mo
Jun
J
Liverpool Center for Materials and Catalysis, Department of Chemistry, University of Liverpool, Liverpool, UK L69 7ZD.
Xu
Lijin
L
Ruan
Jiwu
J
Liu
Shifang
S
Xiao
Jianliang
J
D000438:Alcohols / Q000138:chemical synthesis* / Q000737:chemistry; D000478:Alkylation; D002384:Catalysis; D007093:Imidazoles / Q000737:chemistry*; D052578:Ionic Liquids / Q000737:chemistry*; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry; D010165:Palladium / Q000737:chemistry*; D010720:Phosphines / Q000737:chemistry; D011407:Propane / Q000031:analogs & derivatives / Q000737:chemistry; D013237:Stereoisomerism
D000438:Alcohols; D007093:Imidazoles; D052578:Ionic Liquids; D009942:Organometallic Compounds; D010720:Phosphines; C467590:1,3-bis(diphenylphosphino)propane; D010165:Palladium; D011407:Propane