title: Collecting duct carcinoma of the kidney: a case report with variable immunohistochemistry.
abstract: BACKGROUND
  Collecting duct carcinoma of the kidney is a rare tumour with distinctive clinical and histopathological features. Management of this malignancy remains a challenge because of advanced stage at presentation and aggressive clinical course.
  
  
  OBJECTIVE
  We describe a case of Collecting Duct Carcinoma with variable immunohistochemistry and review the pathology and management.
  
  
  RESULTS
  Our patient died shortly after commencing systemic chemotherapy.
  
  
  CONCLUSIONS
  Advances in immunohistochemistry have aided in diagnosis of this tumour. Early detection and nephrectomy offer the best chance of cure. Newer chemotherapeutic regimens may improve survival in more advanced disease.
authors.affiliation: Dept of Medical Oncology , Mater Misericordiae Hospital, Dublin, Ireland. roisinconnolly@gmail.com
authors.forename: R M
authors.initials: RM
authors.lastname: Connolly
authors.forename: P
authors.initials: P
authors.lastname: Downey
authors.forename: J A
authors.initials: JA
authors.lastname: McCaffrey
mesh_terms: D001859:Bone Neoplasms / Q000556:secondary*; D002292:Carcinoma, Renal Cell / Q000378:metabolism / Q000473:pathology / Q000628:therapy*; D017809:Fatal Outcome; D006801:Humans; D007150:Immunohistochemistry; D007680:Kidney Neoplasms / Q000378:metabolism / Q000473:pathology / Q000628:therapy*; D007685:Kidney Tubules, Collecting / Q000378:metabolism / Q000473:pathology; D008159:Lumbar Vertebrae; D008297:Male; D008875:Middle Aged