title: Computational fluid dynamics verified the advantages of streamlined impeller design in improving flow patterns and anti-haemolysis properties of centrifugal pump.
abstract: Computational fluid dynamics (CFD) technology was applied to predict the flow patterns in the authors' streamlined blood pump and an American bio-pump with straight vanes and shroud, respectively. Meanwhile, haemolysis comparative tests of the two pumps were performed to verify the theoretical analysis. The results revealed that the flow patterns in the streamlined impeller are coincident with its logarithmic vanes and parabolic shroud, and there is neither separate flow nor impact in the authors' pump. In the bio-pump, the main flow has the form of logarithmic spiral in vertical section and parabola in cross section, thus there are both stagnation and swirl between the main flow and the straight vanes and shroud. Haemolysis comparative tests demonstrated that the authors' pump has an index of haemolysis of 0.030, less than that of the bio-pump (0.065).
authors.affiliation: Institute of Biomedical Engineering, Jiangsu University, Zhenjiang, 212013, PR, China.
authors.forename: K X
authors.initials: KX
authors.lastname: Qian
authors.forename: F Q
authors.initials: FQ
authors.lastname: Wang
authors.forename: P
authors.initials: P
authors.lastname: Zeng
authors.forename: W M
authors.initials: WM
authors.lastname: Ru
authors.forename: H Y
authors.initials: HY
authors.lastname: Yuan
authors.forename: Z G
authors.initials: ZG
authors.lastname: Feng
mesh_terms: D000818:Animals; D001243:Assisted Circulation / Q000295:instrumentation* / Q000379:methods; D001783:Blood Flow Velocity / Q000502:physiology*; D001790:Blood Physiological Phenomena; D002498:Centrifugation / Q000295:instrumentation*; D003198:Computer Simulation; D017076:Computer-Aided Design; D004867:Equipment Design / Q000379:methods; D019544:Equipment Failure Analysis / Q000379:methods; D005112:Extracorporeal Circulation / Q000295:instrumentation* / Q000379:methods; D006461:Hemolysis / Q000502:physiology*; D018056:Hemorheology / Q000379:methods*; D008955:Models, Cardiovascular; D013552:Swine