Synthesis of galactofuranose-containing disaccharides using thioimidoyl-type donors.
Four galactofuranose-containing disaccharides have been prepared utilising various thioimidates [Galf-SC(NR)XR'] and suitably protected acceptors as key precursors. We observed that the efficiency of the coupling reactions was particularly dependent on the aglycon present on the furanosyl donor when copper(II) ions were used as the promoter, and that activation could be correlated with the nature of the third heteroatom, X.
Euzen
Ronan
R
Ecole Nationale Supérieure de Chimie de Rennes, UMR CNRS 6226, Avenue du Général Leclerc, F-35700 Rennes, France.
Ferrières
Vincent
V
Plusquellec
Daniel
D
D002240:Carbohydrate Sequence; D004187:Disaccharides / Q000138:chemical synthesis* / Q000737:chemistry*; D005690:Galactose / Q000031:analogs & derivatives*
D004187:Disaccharides; D005690:Galactose