title: Superficial basal cell carcinoma on face treated with 5% imiquimod cream.
abstract: Imiquimod, an immune response modifier, is known to possess both anti-viral and anti-tumor effect. We report our experience of treating a large superficial spreading basal cell carcinoma with 5% imiquimod cream. A 65-year-old male had an asymptomatic, hyperpigmented, slowly progressive, indurated, 3 x 4 cm plaque on the left cheek for two months. Biopsy from the lesion showed features of basal cell carcinoma. The patient was treated with imiquimod 5% cream, topically three times a week for six months with complete resolution of the lesion and without any side-effects. There was no clinical or histological recurrence after three months of stopping the treatment.
authors.affiliation: Department of Dermatology and Venereology, All India Institute of Medical Sciences, New Delhi--110 029, India.
authors.forename: Amit Kumar
authors.initials: AK
authors.lastname: Malhotra
authors.forename: Arika
authors.initials: A
authors.lastname: Bansal
authors.forename: Asit R
authors.initials: AR
authors.lastname: Mridha
authors.forename: Binod K
authors.initials: BK
authors.lastname: Khaitan
authors.forename: Kaushal K
authors.initials: KK
authors.lastname: Verma
mesh_terms: D000368:Aged; D000634:Aminoquinolines / Q000008:administration & dosage*; D002280:Basal Cell Carcinoma / Q000175:diagnosis / Q000188:drug therapy*; D005145:Face / Q000473:pathology; D006801:Humans; D000077271:Imiquimod; D008297:Male; D009824:Ointments; D012878:Skin Neoplasms / Q000175:diagnosis / Q000188:drug therapy*
chemical_list: D000634:Aminoquinolines; D009824:Ointments; D000077271:Imiquimod