[Study on the cholelitholytic effect and safety of the preparation of Chinese medicine compound].
OBJECTIVE
To study the cholelitholytic effect and safety of the preparation of Chinese medicine compound.


METHODS
Experiments were performed to study the efficacy of gallstones dissolution of the preparation of Chinese medicine compound in vitro and in vivo. The toxicity was studied by pathological and blood biochemical changes.


RESULTS
The preparation of Chinese medicine compound dissolved cholesterol and mixing gallstones in 7 days in vitro and in vivo, no influence on the blood biochemistry and the other organs of the rabbits.


CONCLUSIONS
The preparation of Chinese medicine compound is effective and safe for treatment of chololithiasis.
Yang
Hua
H
Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China. yanghua2796@sina.com
Guo
Yu-ning
YN
Yi
Hong
H
Yang
Zhao-xu
ZX
Zhang
Qi-wei
QW
Zhang
Yong-xin
YX
D000818:Animals; D019306:Artemisia / Q000737:chemistry; D002769:Cholelithiasis / Q000188:drug therapy*; D002957:Citrus / Q000737:chemistry; D003228:Conjunctiva / Q000187:drug effects*; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification / Q000627:therapeutic use* / Q000633:toxicity; D005260:Female; D006801:Humans; D066298:In Vitro Techniques; D008297:Male; D051379:Mice; D010946:Plants, Medicinal / Q000737:chemistry; D011817:Rabbits; D011897:Random Allocation
D004365:Drugs, Chinese Herbal