Reproductive outcome of septate uterus after hysteroscopic treatment with neodymium:YAG laser.
OBJECTIVE
The aim of this study was to assess fertility outcome and obstetrical prognosis of 46 patients after hysteroscopic section of uterine septa with neodysmium:yttrium-aluminum-garnet (Nd:YAG) laser.


BACKGROUND
Approximately 15-25% of spontaneous miscarriages are related to Müllerian fusion defects, most of which are associated with uterine septa. Operative hysteroscopy is a safe and effective treatment for uterine septa.


METHODS
Forty-six sterile patients with septate uterus received hysteroscopic metroplasty with Nd:YAG laser. Forty-one patients with incomplete septate uterus were under the guidance of B-ultrasonography, while the other 5 patients with complete septate uterus were treated by laparoscopy.


RESULTS
The metroplasty was successfully conducted in 45 patients, with a success rate of 98% (45 /46). Postoperative follow-up examinations of 28 patients revealed pregnancy within 12 months in 20 patients, 16 of whom acquired term delivery. The pregnancy rate within 1 year was 71%.


CONCLUSIONS
Hysteroscopic treatment of septate uterus with Nd:YAG laser is effective. The cervix may not be excessively dilated, the intraoperative bleeding can be thoroughly controlled, and the procedure under local anesthesia is relatively safe.
Yang
Jing
J
Reproductive Medical Center, Renmin Hospital of Wuhan University, Wuhan, PR of China. DrYangQing@hotmail.com
Yin
Tai-Lang
TL
Yin
Tai-Ung
TU
Xu
Wang-Ming
WM
Xia
Liang-Bin
LB
Xia
Lian-Gbin
LG
Li
Ai-Bin
AB
Hu
Jing
J
D000328:Adult; D005260:Female; D006801:Humans; D015907:Hysteroscopy; D053685:Laser Therapy; D011247:Pregnancy; D018873:Pregnancy Rate; D012189:Retrospective Studies; D014463:Ultrasonography; D014599:Uterus / Q000002:abnormalities* / Q000000981:diagnostic imaging / Q000601:surgery*