[Advances on phytoestrogen intervening breast cancer].
Phytoestrogen is the bioactive substance from plant, with structure is very simliar to that of estrogen. Phytoestrogen is mainly comprises of isoflavone, lignan and coumarin. Epidemiological restrarch shows that the increasing the uptake phytoestrogen of can reduce the morbidities of breast and other cancers. In this paper, the food source, characteristic and relevant researches both in vitro and in vivo were reviewed, and its mechanisms of intervening breast cancer were also discussed.
Zhao
Liang-cai
LC
Anhui College of Traditional Chinese Medicine, Anhui Key Laboratory of Modernized Chinese Material Medical, Hefei 230031, China.
Tang
Li-jian
LJ
Li
Qing-lin
QL
Liu
Jing-gen
JG
D000818:Animals; D000975:Antioxidants / Q000494:pharmacology; D017209:Apoptosis / Q000187:drug effects*; D001943:Breast Neoplasms / Q000201:enzymology / Q000473:pathology*; D045744:Cell Line, Tumor; D003374:Coumarins / Q000494:pharmacology; D004250:DNA Topoisomerases, Type II / Q000378:metabolism; D005260:Female; D006801:Humans; D007529:Isoflavones / Q000494:pharmacology; D017705:Lignans / Q000494:pharmacology; D048789:Phytoestrogens / Q000302:isolation & purification / Q000494:pharmacology*; D010946:Plants, Medicinal / Q000737:chemistry; D011505:Protein-Tyrosine Kinases / Q000378:metabolism
D000975:Antioxidants; D003374:Coumarins; D007529:Isoflavones; D017705:Lignans; D048789:Phytoestrogens; D011505:Protein-Tyrosine Kinases; D004250:DNA Topoisomerases, Type II