Recent results: biomarkers of aging.
This communication reviews recent papers attempting to identify Biomarkers of Aging (BoA). A BoA is a biological parameter that will predict functional capability at some later age. Few, if any, BoA have been found and this review describes the recent search for BoA. Among others that have been put forward are IL6 and other markers of inflammation, allostatic load, and corticosterone, which have been described primarily in humans. Work in model systems as well as theoretical work are also reviewed.
Johnson
Thomas E
TE
University of Colorado, Institute for Behavioral Genetics, Box 447, Boulder, CO 80309, USA. johnsont@colorado.edu
D000368:Aged; D000375:Aging / Q000235:genetics / Q000502:physiology*; D000818:Animals; D015415:Biomarkers / Q000032:analysis*; D017173:Caenorhabditis elegans; D003072:Cognition Disorders / Q000503:physiopathology; D016207:Cytokines / Q000276:immunology; D004272:DNA, Mitochondrial / Q000235:genetics; D006801:Humans; D015850:Interleukin-6 / Q000276:immunology; D023421:Models, Animal; D018570:Risk Assessment / Q000379:methods; D012959:Socioeconomic Factors; D016615:Telomere / Q000235:genetics
D015415:Biomarkers; D016207:Cytokines; D004272:DNA, Mitochondrial; D015850:Interleukin-6