title: Chronically mountable goggles for persistent exposure to single orientation.
abstract: To examine the effect of experience on the developmental plasticity of functional maps in the visual cortex, we need to establish a method for a stable visual experience manipulation under the freely moving condition. For this purpose, we fabricated goggles that are chronically mounted stably on the animal's head, but easy to replace according to the animal's growth. Here we report the design of the goggles and the method of mounting them on the head of animals. By this method, combined with the intrinsic signal optical imaging technique, we were able to observe a rapid and robust reorganization of orientation maps.
authors.affiliation: Laboratory for Visual Neurocomputing, Brain Science Institute, RIKEN 2-1, Hirosawa, Wako, Saitama 351-0198, Japan. shigeru@riken.jp
authors.forename: Shigeru
authors.initials: S
authors.lastname: Tanaka
authors.forename: Toshiki
authors.initials: T
authors.lastname: Tani
authors.forename: Jérôme
authors.initials: J
authors.lastname: Ribot
authors.forename: Tadashi
authors.initials: T
authors.lastname: Yamazaki
mesh_terms: D000375:Aging / Q000502:physiology; D000818:Animals; D000831:Animals, Newborn; D001931:Brain Mapping / Q000295:instrumentation / Q000379:methods; D002415:Cats; D005139:Eyeglasses / Q000592:standards; D009482:Neurophysiology / Q000295:instrumentation* / Q000379:methods; D055095:Optics and Photonics / Q000295:instrumentation; D009949:Orientation / Q000502:physiology*; D010775:Photic Stimulation / Q000295:instrumentation* / Q000379:methods; D012160:Retina / Q000502:physiology; D012815:Signal Processing, Computer-Assisted; D014793:Visual Cortex / Q000254:growth & development; D014794:Visual Fields / Q000502:physiology; D014795:Visual Pathways / Q000254:growth & development*; D014796:Visual Perception / Q000502:physiology*