Nanobiomaterial applications in orthopedics.
Advancements in nanobiotechnology are revolutionizing our capability to understand biological intricacies and resolve biological and medical problems by developing subtle biomimetic techniques. Nanocomposites and nanostructured materials are believed to play a pivotal role in orthopedic research since bone itself is a typical example of a nanocomposite. This article reviews current strategies using nanobiomaterials to improve current orthopedic materials and examines their applications in bone tissue engineering. Preliminary investigations support the potential of nanobiomaterials in orthopedic applications; however, significant advancements are necessary to achieve clinical use. Overall, current trends in nanobiotechnology foreshadow a bright future through the use of nanobiomaterials in the orthopedic domain.
Christenson
Elizabeth M
EM
Department of Bioengineering-MS142, Rice University, PO Box 1892, Houston, Texas 77251-1892, USA.
Anseth
Kristi S
KS
van den Beucken
Jeroen J J P
JJ
Chan
Casey K
CK
Ercan
Batur
B
Jansen
John A
JA
Laurencin
Cato T
CT
Li
Wan-Ju
WJ
Murugan
Ramalingam
R
Nair
Lakshmi S
LS
Ramakrishna
Seeram
S
Tuan
Rocky S
RS
Webster
Thomas J
TJ
Mikos
Antonios G
AG
D001672:Biocompatible Materials; D040761:Biomimetic Materials; D008855:Microscopy, Electron, Scanning; D053761:Nanocomposites; D036103:Nanotechnology / Q000639:trends*; D009985:Orthopedics / Q000639:trends*; D019736:Prostheses and Implants; D023822:Tissue Engineering / Q000379:methods
D001672:Biocompatible Materials