Gold-catalyzed and N-iodosuccinimide-mediated cyclization of gamma-substituted allenamides.
Chiral gamma-substituted allenamides have been shown to undergo efficient gold-catalyzed and N-iodosuccinimide-mediated cyclization to highly functionalized dihydrofurans. These reactions proceed rapidly and without loss of stereochemistry.
Hyland
Christopher J T
CJ
Department of Chemistry, Colorado State University, Fort Collins, Colorado 80523, USA.
Hegedus
Louis S
LS
D000466:Alkadienes / Q000737:chemistry*; D000577:Amides / Q000737:chemistry*; D002384:Catalysis; D003500:Cyclization; D005663:Furans / Q000737:chemistry*; D006046:Gold / Q000737:chemistry*; D015394:Molecular Structure; D013237:Stereoisomerism; D013388:Succinimides / Q000737:chemistry*
D000466:Alkadienes; D000577:Amides; D005663:Furans; D013388:Succinimides; C008155:N-iodosuccinimide; C025947:propadiene; D006046:Gold