title: Acute lymphoblastic leukemia associated with brucellosis in two patients with fever and pancytopenia.
abstract: Brucellosis is a disease involving the lymphoproliferative system, which may lead to changes in the hematological parameters; however, pancytopenia is a rare finding. However, malignant diseases in association with brucellosis are rarely the cause of pancytopenia. Herein, two cases with fever and pancytopenia, diagnosed as simultaneous acute lymphoblastic leukemia and brucellosis are presented. Anti-leukemic therapy and brucellosis treatment were administered simultaneously, and normal blood parameters obtained. The first patient is in complete remission; the other recovered from the brucellosis, but later died due to a leukemic relapse.
authors.affiliation: Department of Hematology-Oncology, Dedeman Oncology Hospital, Erciyes University School of Medicine, 38039, Kayseri, Turkey. beser@erciyes.edu.tr
authors.forename: Bulent
authors.initials: B
authors.lastname: Eser
authors.forename: Fevzi
authors.initials: F
authors.lastname: Altuntas
authors.forename: Isin
authors.initials: I
authors.lastname: Soyuer
authors.forename: Ozlem
authors.initials: O
authors.lastname: Er
authors.forename: Ozlem
authors.initials: O
authors.lastname: Canoz
authors.forename: Hasan Senol
authors.initials: HS
authors.lastname: Coskun
authors.forename: Mustafa
authors.initials: M
authors.lastname: Cetin
authors.forename: Ali
authors.initials: A
authors.lastname: Unal
mesh_terms: D000328:Adult; D002006:Brucellosis / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D005260:Female; D005334:Fever; D006801:Humans; D010198:Pancytopenia / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000150:complications* / Q000473:pathology / Q000628:therapy