Effects of misoprostol and taurine on monochloramine ulcerogenesis in rats.
We compared gastroprotective characteristics of synthetic prostaglandin E1 misoprostol and amino acid taurine on rat model of monochloramine injury to the gastric mucosa. Both substances exhibited a pronounced gastroprotective effect.
Spasov
A A
AA
Department of Pharmacology, Department of Forensic Medicine, Volgograd State Medical University. farm@interdacom.ru
Chernikov
M V
MV
Speranskaya
A S
AS
Zaichenko
S I
SI
D000818:Animals; D002700:Chloramines / Q000633:toxicity*; D005260:Female; D008297:Male; D016595:Misoprostol / Q000494:pharmacology*; D051381:Rats; D013276:Stomach Ulcer / Q000139:chemically induced* / Q000517:prevention & control*; D013654:Taurine / Q000494:pharmacology*
D002700:Chloramines; D016595:Misoprostol; D013654:Taurine; C030816:chloramine