title: [Study on the cholelitholytic effect and safety of the preparation of Chinese medicine compound].
abstract: OBJECTIVE
  To study the cholelitholytic effect and safety of the preparation of Chinese medicine compound.
  
  
  METHODS
  Experiments were performed to study the efficacy of gallstones dissolution of the preparation of Chinese medicine compound in vitro and in vivo. The toxicity was studied by pathological and blood biochemical changes.
  
  
  RESULTS
  The preparation of Chinese medicine compound dissolved cholesterol and mixing gallstones in 7 days in vitro and in vivo, no influence on the blood biochemistry and the other organs of the rabbits.
  
  
  CONCLUSIONS
  The preparation of Chinese medicine compound is effective and safe for treatment of chololithiasis.
authors.affiliation: Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China. yanghua2796@sina.com
authors.forename: Hua
authors.initials: H
authors.lastname: Yang
authors.forename: Yu-ning
authors.initials: YN
authors.lastname: Guo
authors.forename: Hong
authors.initials: H
authors.lastname: Yi
authors.forename: Zhao-xu
authors.initials: ZX
authors.lastname: Yang
authors.forename: Qi-wei
authors.initials: QW
authors.lastname: Zhang
authors.forename: Yong-xin
authors.initials: YX
authors.lastname: Zhang
mesh_terms: D000818:Animals; D019306:Artemisia / Q000737:chemistry; D002769:Cholelithiasis / Q000188:drug therapy*; D002957:Citrus / Q000737:chemistry; D003228:Conjunctiva / Q000187:drug effects*; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification / Q000627:therapeutic use* / Q000633:toxicity; D005260:Female; D006801:Humans; D066298:In Vitro Techniques; D008297:Male; D051379:Mice; D010946:Plants, Medicinal / Q000737:chemistry; D011817:Rabbits; D011897:Random Allocation
chemical_list: D004365:Drugs, Chinese Herbal