title: Efficient and direct synthesis of poly-substituted indeno[1,2-b]quinolines assisted by p-toluene sulfonic acid using high-temperature water and microwave heating via one-pot, three-component reaction.
abstract: Reactions of aldehydes, 1,3-indanedione and enaminones were successfully carried out using p-toluene sulfonic acid (p-TsOH) as a catalyst and high-temperature water as a solvent under microwave irradiation. This method provided several advantages such as rapid reaction times, high yields, and a simple workup procedure. In addition, a possible mechanism to account for the reaction was proposed.
authors.affiliation: Department of Chemistry, Xuzhou Normal University, Key Laboratory of Biotechnology for Medicinal Plants, Xuzhou, Jiangsu, 211116, P R China. laotu@xznu.edu.cn
authors.forename: Shu-Jiang
authors.initials: SJ
authors.lastname: Tu
authors.forename: Bo
authors.initials: B
authors.lastname: Jiang
authors.forename: Jun-Yong
authors.initials: JY
authors.lastname: Zhang
authors.forename: Run-Hong
authors.initials: RH
authors.lastname: Jia
authors.forename: Yan
authors.initials: Y
authors.lastname: Zhang
authors.forename: Chang-Sheng
authors.initials: CS
authors.lastname: Yao
mesh_terms: D002384:Catalysis; D006358:Hot Temperature; D008872:Microwaves; D011804:Quinolines / Q000138:chemical synthesis* / Q000737:chemistry; D013451:Sulfonic Acids / Q000737:chemistry*; D014050:Toluene / Q000737:chemistry*; D014867:Water / Q000737:chemistry*
chemical_list: D011804:Quinolines; D013451:Sulfonic Acids; D014867:Water; D014050:Toluene