Tribological monitoring of drugs used for the treatment of arthropathies.
Lubricating capacity of drugs injected into articular cavity were tested using a pendulum tribometer. The findings indicate that friction coefficient for a pair simulating metallopolymeric articular endoprosthesis is changed under the effect of electromagnetic field after lubrication. Regularities of these changes depend on the nature and mechanism of action of drugs. A method for rapid evaluation of the lubricating characteristics of drugs is proposed for optimizing their therapeutic effect on joints.
Pinchuk
L S
LS
Hermetology Department, V. A. Belyi Institute of Mechanics of Metallopolymeric Systems, National Academy of Sciences, Belarus, Gomel.
Chernyakova
Yu M
YM
Kadolich
Z V
ZV
Nikolaev
V I
VI
D016903:Drug Monitoring / Q000379:methods*; D006801:Humans; D007592:Joint Diseases / Q000188:drug therapy*