title: Why pain gets worse: the mechanism of heat hyperalgesia.
authors.affiliation: Department of Pharmacology, University of Cambridge, Cambridge, CB2 1PD, UK.
authors.forename: Xuming
authors.initials: X
authors.lastname: Zhang
authors.forename: Peter A
authors.initials: PA
authors.lastname: McNaughton
mesh_terms: D017868:Cyclic AMP-Dependent Protein Kinases / Q000502:physiology; D018450:Disease Progression; D006801:Humans; D006930:Hyperalgesia / Q000503:physiopathology*; D020932:Nerve Growth Factor / Q000502:physiology; D009475:Neurons, Afferent / Q000502:physiology*; D009619:Nociceptors / Q000502:physiology; D010146:Pain / Q000503:physiopathology*; D019269:Phosphatidylinositol 4,5-Diphosphate / Q000502:physiology; D051744:Protein Kinase C-epsilon / Q000502:physiology; D050916:TRPV Cation Channels / Q000502:physiology; D019061:src-Family Kinases / Q000502:physiology
chemical_list: D019269:Phosphatidylinositol 4,5-Diphosphate; D050916:TRPV Cation Channels; C494482:TRPV1 protein, human; D020932:Nerve Growth Factor; D019061:src-Family Kinases; D017868:Cyclic AMP-Dependent Protein Kinases; D051744:Protein Kinase C-epsilon