title: Ultrasound screening for Opisthorchis viverrini-associated cholangiocarcinomas: experience in an endemic area.
abstract: In Thailand, liver cancer is the most common malignancy in males and the third most common among females. In the Northeast region, cholangiocarcinoma (CHCA) is the prevalent type, with Opisthorchis viverrini (OV), an endemic liver fluke, being considered the cause. We evaluated the role of ultrasound (U/S) for cholangiocarcinoma screening as part of a larger cohort to characterize the linkage between liver fluke infestation and CHCA in Khon Kaen (Northeast Thailand). Most people (77%) had normal U/S findings while only 0.5% had suspected CHCA; thus, U/S should be used primarily for those with the highest risk, presenting symptoms and/or being OV positive.
authors.affiliation: Department of Radiology, Cancer Unit, Faculty of Medicine, Khon Kaen University, Khon Kaen, 40002, Thailand. eimmai@kku.ac.th
authors.forename: Eimorn
authors.initials: E
authors.lastname: Mairiang
authors.forename: Jitjaroen
authors.initials: J
authors.lastname: Chaiyakum
authors.forename: Nitaya
authors.initials: N
authors.lastname: Chamadol
authors.forename: Vallop
authors.initials: V
authors.lastname: Laopaiboon
authors.forename: Jiraporn
authors.initials: J
authors.lastname: Srinakarin
authors.forename: Jaturat
authors.initials: J
authors.lastname: Kunpitaya
authors.forename: Supannee
authors.initials: S
authors.lastname: Sriamporn
authors.forename: Kritika
authors.initials: K
authors.lastname: Suwanrungruang
authors.forename: Vanchai
authors.initials: V
authors.lastname: Vatanasapt
mesh_terms: D000328:Adult; D000368:Aged; D000818:Animals; D001650:Bile Duct Neoplasms / Q000000981:diagnostic imaging* / Q000469:parasitology; D001653:Bile Ducts, Intrahepatic / Q000000981:diagnostic imaging* / Q000469:parasitology; D018281:Cholangiocarcinoma / Q000000981:diagnostic imaging* / Q000469:parasitology; D019353:Endemic Diseases; D005210:Fasciola hepatica; D005260:Female; D006801:Humans; D015994:Incidence; D008113:Liver Neoplasms / Q000000981:diagnostic imaging* / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D009889:Opisthorchiasis / Q000000981:diagnostic imaging* / Q000453:epidemiology; D009891:Opisthorchis; D015995:Prevalence; D013785:Thailand / Q000453:epidemiology; D014463:Ultrasonography