Secondary cervical dystonia in iatrogenic hypoparathyroidism associated with extensive brain calcifications.
Cervical dystonia (CD) is usually idiopathic, without a known aetiology. Hypoparathyroidism, both primary and secondary, can be associated with brain calcifications and various clinical neurological features. Anecdotal evidence suggests that patients affected by hypoparathyroidism show a rapid-onset oral dyskinesia after use of neuroleptic drugs. We report the case of a 60-year-old woman with CD, iatrogenic hypoparathyroidism and extensive brain calcifications. On the basis of the clinical features and the localization of the brain calcifications we suppose that they may have played a role in the development of this CD. This case may prove to be, after a review of literature, the first report of CD secondary to iatrogenic hypoparathyroidism in a patient with extensive brain calcifications.
Mancini
Francesca
F
Parkinson's Disease and Movement Disorders Unit, C. Mondino Institute of Neurology Foundation, Pavia, Italy. francesca.mancini@mondino.it
Zangaglia
Roberta
R
Cristina
Silvano
S
Tassorelli
Cristina
C
Uggetti
Carla
C
Nappi
Giuseppe
G
Pacchetti
Claudio
C
D001927:Brain Diseases / Q000209:etiology* / Q000473:pathology; D002114:Calcinosis / Q000209:etiology* / Q000473:pathology; D005260:Female; D006801:Humans; D007011:Hypoparathyroidism / Q000150:complications* / Q000473:pathology; D007049:Iatrogenic Disease; D008875:Middle Aged; D014103:Torticollis / Q000209:etiology*