[A case of primary neuroendocrine carcinoma of liver presenting with liver abscess].
Primary hepatic neuroendocrine cell carcinoma is a very rare tumor. We experienced a 75-year-old woman with primary hepatic neuroendocrine carcinoma presenting with pyogenic liver abscess. Abdominal CT scan revealed a multiseptated liver abscess and an enlarged lymph node in portocaval portion. We performed percutaneous drainage of the liver abscess, but the amount of drained pus did not decrease after 20 days. The follow-up abdominal CT scan showed that the cystic portion of liver abscess had been replaced by the solid tumor. Microscopic examination of the tumor tissue showed nests of epithelial cells with uniform round hyperchromatic nuclei and high nuclear to cytoplasmic ratio. Immunohistochemical staining was strongly positive for synaptophysin and chromogranin A.
Lee
Seuk Hyun
SH
Department of Internal Medicine, Ilsan Paik Hospital, Inje University College of Medicine, Ilsan-Gu, Goyang, Korea.
Kim
Kyung-Ah
KA
Lee
June Sung
JS
Oh
Dong Hoon
DH
Bae
Won Ki
WK
Kim
Nam-Hoon
NH
Moon
Young Soo
YS
Kim
Han Seong
HS
D000368:Aged; D018278:Carcinoma, Neuroendocrine / Q000175:diagnosis* / Q000473:pathology; D053379:Chromogranin A / Q000032:analysis / Q000276:immunology; D004322:Drainage; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008100:Liver Abscess / Q000000981:diagnostic imaging* / Q000601:surgery; D008113:Liver Neoplasms / Q000175:diagnosis* / Q000473:pathology; D011860:Radiography, Abdominal; D016708:Synaptophysin / Q000032:analysis / Q000276:immunology; D014057:Tomography, X-Ray Computed
D053379:Chromogranin A; D016708:Synaptophysin