title: Selection for more of the same product as a force to enhance concerted evolution of duplicated genes.
abstract: The duration of concerted evolution after gene duplication is highly variable across genes. To identify the cause of the variation, we analyzed of duplicated genes in yeast that originate from a whole genome duplication event. There appears to be a strong positive correlation between the duration of concerted evolution and the gene expression level. This observation can be explained by selection favoring more of the same product, which could enhance concerted evolution in dosage-sensitive genes.
authors.affiliation: University of Texas Health Science Center at Houston School of Public Health, Human Genetics Center, 1200 Hermann Pressler, Houston, TX 77030, USA.
authors.forename: Ryuichi P
authors.initials: RP
authors.lastname: Sugino
authors.forename: Hideki
authors.initials: H
authors.lastname: Innan
mesh_terms: D019143:Evolution, Molecular; D005656:Fungal Proteins / Q000378:metabolism; D018628:Gene Dosage; D020440:Gene Duplication; D015966:Gene Expression Regulation, Fungal; D005800:Genes, Fungal; D014644:Genetic Variation; D016681:Genome, Fungal; D008957:Models, Genetic; D010802:Phylogeny; D012270:Ribosomes / Q000378:metabolism; D012441:Saccharomyces cerevisiae / Q000235:genetics* / Q000378:metabolism; D012641:Selection, Genetic; D013696:Temperature
chemical_list: D005656:Fungal Proteins