title: A prospective, longitudinal study of feeding skills in a cohort of babies with cleft conditions.
abstract: OBJECTIVE
  To examine the natural history of feeding skills in babies with clefts and identify risk factors and predictors of poor feeding.
  
  
  METHODS
  Sixty-two babies with clefts were examined at 2 weeks, 3 months, and 14 months of age.
  
  
  METHODS
  Feeding ability, oral motor function, and feeding efficiency were assessed. Univariate analyses were used to determine whether oral motor function and sequelae varied according to feeding ability or cleft condition. Multivariable logistic regressions were used to determine risk factors for poor feeding.
  
  
  RESULTS
  Poor feeding skills were detected in one third of newborns. The prevalence of poor feeding reduced to 19% at 3 months of age and 15% at 14 months of age. Oral motor dysfunction and sequelae (particularly nasal regurgitation) were more commonly observed in babies with poor feeding skills irrespective of comorbidity. The main risk factor for poor feeding was a diagnosis of syndrome or Pierre Robin sequence (PRS). At 2 weeks of age, babies with syndrome or PRS were 15 times more likely to have poor feeding skills than their nonsyndromic counterparts. When syndrome or PRS was controlled for, babies with cleft palate and cleft lip and palate were equally likely to have poor feeding skills. Parental report of feeding efficiency was predictive of poor feeding in young babies.
  
  
  CONCLUSIONS
  Poor feeding skills are relatively common in newborns with cleft palate and cleft lip and palate. Treatment for feeding problems may be needed beyond the first year of life, especially for babies born with PRS or a syndrome.
authors.affiliation: Murdoch Children's Research Institute and Speech Pathology Department, Royal Children's Hospital, Flemington Road, Parkville 3052, Victoria, Australia. julie.reid@rch.org.au
authors.forename: Julie
authors.initials: J
authors.lastname: Reid
authors.forename: Nicky
authors.initials: N
authors.lastname: Kilpatrick
authors.forename: Sheena
authors.initials: S
authors.lastname: Reilly
mesh_terms: D000402:Airway Obstruction / Q000503:physiopathology; D001903:Bottle Feeding; D001942:Breast Feeding; D002971:Cleft Lip / Q000503:physiopathology*; D002972:Cleft Palate / Q000503:physiopathology*; D015331:Cohort Studies; D003371:Cough / Q000503:physiopathology; D005247:Feeding Behavior / Q000502:physiology*; D005260:Female; D005500:Follow-Up Studies; D005683:Gagging / Q000502:physiology; D006801:Humans; D007223:Infant; D018730:Infant Behavior / Q000502:physiology*; D007231:Infant, Newborn; D008137:Longitudinal Studies; D008297:Male; D010855:Pierre Robin Syndrome / Q000503:physiopathology; D011446:Prospective Studies; D053120:Respiratory Aspiration / Q000503:physiopathology; D012307:Risk Factors; D013577:Syndrome; D013997:Time Factors; D015430:Weight Gain