title: [Case of eosinophilic bronchitis and bronchiolitis associated with increased level of serum CEA in asthmatics].
abstract: A 50-year-old asthmatic woman showed peripheral blood eosinophilia, significantly increased level of CEA in serum (102.5ng/ml), and atelectasis of the right middle lobe on chest radiograph and CT. The level of CEA subsequently increased further, and then decreased with systemic corticosteroid therapy. Pathological findings of surgically biopsied lung showed eosinophilic broncho-bronchiolitis, without malignant cells. Two years later, chest CT demonstrated various findings such as mucoid impaction, peripheral bronchiectasis and centrilobular nodules, but allergic bronchopulmonary mycosis was not proved. These findings suggest that the eosinophilic bronchiolar inflammation in bronchial asthma caused an increase in serum CEA levels and various findings on chest CT.
authors.affiliation: Clinical Research Center for Allergy and Rheumatology, National Hospital Organization, Sagamihara National Hospital.
authors.forename: Takahiro
authors.initials: T
authors.lastname: Tsuburai
authors.forename: Yoshinori
authors.initials: Y
authors.lastname: Kawabata
authors.forename: Naomi
authors.initials: N
authors.lastname: Tsurikisawa
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Mitomi
authors.forename: Chiyako
authors.initials: C
authors.lastname: Oshikata
authors.forename: Emiko
authors.initials: E
authors.lastname: Ono
authors.forename: Mamoru
authors.initials: M
authors.lastname: Ohtomo
authors.forename: Yuji
authors.initials: Y
authors.lastname: Maeda
authors.forename: Masami
authors.initials: M
authors.lastname: Taniguchi
authors.forename: Kazuo
authors.initials: K
authors.lastname: Akiyama
mesh_terms: D001249:Asthma / Q000150:complications* / Q000000981:diagnostic imaging; D001988:Bronchiolitis / Q000000981:diagnostic imaging / Q000209:etiology*; D002272:Carcinoembryonic Antigen / Q000097:blood*; D004802:Eosinophilia / Q000000981:diagnostic imaging / Q000209:etiology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D014057:Tomography, X-Ray Computed
chemical_list: D002272:Carcinoembryonic Antigen