title: Antimycobacterial activity of econazole against multidrug-resistant strains of Mycobacterium tuberculosis.
abstract: This study evaluated the antimycobacterial activity of econazole against multidrug-resistant (MDR) strains of Mycobacterium tuberculosis. The minimum inhibitory concentration (MIC(90)) and minimum bactericidal concentration (MBC(>99.99)) against MDR strains were found to be 0.120-0.125 microg/mL and 0.125-0.150 microg/mL, respectively, demonstrating the antimycobacterial potential of econazole.
authors.affiliation: Department of Biochemistry, Postgraduate Institute of Medical Education & Research, Chandigarh 160 012, India.
authors.forename: Zahoor
authors.initials: Z
authors.lastname: Ahmad
authors.forename: Sadhna
authors.initials: S
authors.lastname: Sharma
authors.forename: G K
authors.initials: GK
authors.lastname: Khuller
authors.forename: Pushpendra
authors.initials: P
authors.lastname: Singh
authors.forename: Jaya
authors.initials: J
authors.lastname: Faujdar
authors.forename: V M
authors.initials: VM
authors.lastname: Katoch
mesh_terms: D000995:Antitubercular Agents / Q000494:pharmacology*; D024901:Drug Resistance, Multiple, Bacterial; D004464:Econazole / Q000494:pharmacology*; D006801:Humans; D008826:Microbial Sensitivity Tests / Q000379:methods / Q000592:standards; D009169:Mycobacterium tuberculosis / Q000187:drug effects* / Q000254:growth & development
chemical_list: D000995:Antitubercular Agents; D004464:Econazole