Impact of influenza vaccination on major cause-specific mortality.
The efficacy of influenza vaccination is not well understood for major cause-specific mortality except pneumonia. For 10 months we followed the mortality data of 35,637 vaccinated elderly (>65 years old) in a county with 102,698 elderly in southern Taiwan. A multivariate Cox model showed that vaccination was significantly associated with lower mortality for all causes, [hazards ratio (HR)=0.56], stroke (HR=0.35), renal disease (HR=0.40), diabetes mellitus (HR=0.45), pneumonia (HR=0.47), COPD (HR=0.55), malignancy (HR=0.74), and heart diseases (HR=0.78), p<0.05. Influenza vaccination was strongly associated with reducing major cause-specific mortality.
Wang
Chong-Shan
CS
Community Medicine Research Centre and Institute of Public Health, National Yang-Ming University, Taipei, Taiwan.
Wang
Shan-Tair
ST
Lai
Ching-Te
CT
Lin
Li-Jen
LJ
Chou
Pesus
P
D000368:Aged; D000704:Analysis of Variance; D005260:Female; D006801:Humans; D007252:Influenza Vaccines / Q000627:therapeutic use*; D007251:Influenza, Human / Q000401:mortality* / Q000517:prevention & control*; D008297:Male; D016016:Proportional Hazards Models; D012307:Risk Factors; D013624:Taiwan / Q000453:epidemiology; D016896:Treatment Outcome; D014611:Vaccination / Q000706:statistics & numerical data*
D007252:Influenza Vaccines