title: Mechanical properties and biocompatibility of soluble eggshell membrane protein/poly(vinyl alcohol) blend films.
abstract: Poly(vinyl alcohol) (PVA) has been blended with soluble eggshell membrane protein (SEP) to improve the mechanical properties of SEP film that is brittle. Tensile strength and elongation-at-break increase with increasing amount of PVA. When the SEP/PVA proportion is 1:1, a strong and flexible film is obtained, having a tensile strength of 22.7 MPa and elongation-at-break of 106%. Although scanning electron microscopy observation of the freeze-fractured cross-section shows microphase separation, interaction between SEP and PVA exists, as revealed by FT-IR. NIH3T3 cell culture demonstrates that SEP/PVA blend films with up to 50% of PVA show biocompatibility comparable to pure SEP film.
authors.affiliation: Institute of Polymer Science and Engineering, Department of Chemical Engineering, School of Materials Science and Engineering, Tsinghua University, Beijing 100084, P R. China.
authors.forename: Feng
authors.initials: F
authors.lastname: Yi
authors.forename: Jian-Wei
authors.initials: JW
authors.lastname: Lu
authors.forename: Zhao-Xia
authors.initials: ZX
authors.lastname: Guo
authors.forename: Jian
authors.initials: J
authors.lastname: Yu
mesh_terms: D016475:3T3 Cells; D000818:Animals; D001672:Biocompatible Materials / Q000737:chemistry* / Q000494:pharmacology; D002152:Calorimetry, Differential Scanning; D049109:Cell Proliferation / Q000187:drug effects; D004527:Egg Proteins / Q000737:chemistry*; D008567:Membranes, Artificial; D051379:Mice; D008855:Microscopy, Electron, Scanning; D008858:Microscopy, Phase-Contrast; D011142:Polyvinyl Alcohol / Q000737:chemistry*; D017550:Spectroscopy, Fourier Transform Infrared; D013718:Tensile Strength; D014961:X-Ray Diffraction
chemical_list: D001672:Biocompatible Materials; D004527:Egg Proteins; D008567:Membranes, Artificial; D011142:Polyvinyl Alcohol