title: Randomized clinical trial of Lichtenstein's operation versus mesh plug for inguinal hernia repair.
abstract: BACKGROUND
  Two of the most commonly used open prosthetic tension-free techniques for inguinal hernia repair are Lichtenstein's operation and the mesh plug repair. The technique of choice remains a subject of ongoing debate. The objective of the present investigation was to compare the two surgical procedures with respect to associated morbidity and recurrence rates.
  
  
  METHODS
  Five hundred and ninety-five patients with 700 primary or recurrent inguinal hernias were randomized to undergo either Lichtenstein's operation or mesh plug repair. The primary endpoint of the investigation was the recurrence rate 1 year after surgery. Secondary endpoints were perioperative complications and reoperation rates.
  
  
  RESULTS
  At 12-month follow-up, 597 hernia repairs (85.3 per cent) were evaluated. There were no significant differences regarding recurrence rates and perioperative complications. However, there was a significant difference in the overall reoperation rate between the two treatment groups, with 13 reoperations (4.2 per cent) in the Lichtenstein group and four (1.4 per cent) in the mesh plug group (P = 0.047).
  
  
  CONCLUSIONS
  Lichtenstein's operation and the mesh plug repair are comparable with respect to perioperative complications and recurrence rates.
authors.affiliation: Department of Surgery, Divisions of General Surgery and Surgical Research, University Hospital Basle, Basle, Switzerland.
authors.forename: D M
authors.initials: DM
authors.lastname: Frey
authors.forename: A
authors.initials: A
authors.lastname: Wildisen
authors.forename: C T
authors.initials: CT
authors.lastname: Hamel
authors.forename: M
authors.initials: M
authors.lastname: Zuber
authors.forename: D
authors.initials: D
authors.lastname: Oertli
authors.forename: J
authors.initials: J
authors.lastname: Metzger
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D013505:Digestive System Surgical Procedures / Q000009:adverse effects / Q000379:methods*; D005260:Female; D005500:Follow-Up Studies; D006552:Hernia, Inguinal / Q000601:surgery*; D006801:Humans; D007431:Intraoperative Complications / Q000209:etiology; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000209:etiology; D011446:Prospective Studies; D012008:Recurrence; D012086:Reoperation; D013526:Surgical Mesh; D016896:Treatment Outcome