[Chemical constituents of unsaponifiable matter from seed oil of Momordica cochinchinensis].
OBJECTIVE
To study the chemical constituents of unsaponifiable matter from the seed oil of Momordica cochinchinensis.


METHODS
The fatty oil from the seeds of M. cochinchinensis was extracted with petroleum ether, and the saponification was carried out with potassium hydroxide. The unsaponifiable matter was isolated and purified by silica gel column chromatography, and the structures of their constituents were elucidated by means of IR, MS, 1H-NMR, and authentic chemicals.


RESULTS
Karounidiol (1), isokarounidiol (2), 5-dehydrokarounidiol (3), 7-oxodihydrokarounidiol (4), beta-sitosterol (5), stigmast-7-en-3beta-ol (6), and stigmast-7,22-dien-3beta-ol (7) were elucidated.


CONCLUSIONS
These compounds were found in this plant for the first time.
Kan
Lian-Di
LD
Sir Sun Sun Shaw Hospital, Medical College of Zhejiang University, Hangzhou 310016, China.
Hu
Quan
Q
Chao
Zhi-Mao
ZM
Song
Xiao
X
Cao
Xue-Li
XL
D015394:Molecular Structure; D029775:Momordica / Q000737:chemistry*; D009828:Oleanolic Acid / Q000031:analogs & derivatives* / Q000737:chemistry / Q000302:isolation & purification; D010938:Plant Oils / Q000737:chemistry / Q000302:isolation & purification; D010946:Plants, Medicinal / Q000737:chemistry*; D012639:Seeds / Q000737:chemistry; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification*
D010938:Plant Oils; D014315:Triterpenes; C088116:karounidiol; C076913:7-oxodihydrokarounidiol; D009828:Oleanolic Acid