title: Aprotinin; friend or foe? A review of recent medical literature.
abstract: Recent articles published in peer review journals have questioned the safety of using aprotinin in patients having heart surgery. Also, evidence has been published to suggest an increase in renal events in patients given aprotinin when compared to those where tranexamic acid was used. The present review will focus principally on the first of these articles in relation to previously published data and experience.
authors.affiliation: Royal Brompton and Harefield NHS Trust, Harefield Hospital, Department of Cardiothoracic Anaesthesiaand Critical Care, Harefield, UK. dave@tharg.demon.co.uk
authors.forename: D
authors.initials: D
authors.lastname: Royston
authors.forename: N
authors.initials: N
authors.lastname: van Haaften
authors.forename: P
authors.initials: P
authors.lastname: De Vooght
mesh_terms: D007611:Aprotinin / Q000009:adverse effects* / Q000494:pharmacology*; D064420:Drug-Related Side Effects and Adverse Reactions; D006801:Humans; D012307:Risk Factors; D016896:Treatment Outcome
chemical_list: D007611:Aprotinin