Predicting treatment response in chronic, acquired demyelinating neuropathies.
Chronic inflammatory demyelinating polyradiculopathy is an immune-mediated neuropathy that was first described approximately 30 years ago. Since that time an increasingly wide spectrum of chronic acquired demyelinating polyneuropathies exhibiting different phenotypes, clinical course and treatment responses to immunomodulatory treatment have been described. Several new therapeutic agents have been prescribed for such conditions, some with promising results. This review summarizes what is presently known about the clinical courses, treatment responses and predictors of response of the chronic inflammatory demyelinating polyradiculopathy subgroups.
Chan
Yee-Cheun
YC
National University Hospital, Division of Neurology, 5 Lower Kent Ridge Road, 119074 Sinagpore. yeecheun@yahoo.com.sg
Wilder-Smith
Einar
E
D002908:Chronic Disease; D006801:Humans; D020277:Polyradiculoneuropathy, Chronic Inflammatory Demyelinating / Q000175:diagnosis* / Q000276:immunology / Q000628:therapy*; D011237:Predictive Value of Tests