Ceric ammonium nitrate promoted oxidation of oxazoles.
The ceric ammonium nitrate promoted oxidations of 4,5-diphenyloxazoles and oxazoles with various substitution patterns have been investigated. This transformation results in the formation of the corresponding imide in good yield and tolerates a wide variety of functional groups and substituents on the oxazole moiety. [reaction: see text].
Evans
David A
DA
Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts 02138, USA. evans@chemistry.harvard.edu
Nagorny
Pavel
P
Xu
Risheng
R
D002563:Cerium / Q000737:chemistry*; D007094:Imides / Q000138:chemical synthesis; D010080:Oxazoles / Q000737:chemistry*; D016877:Oxidants / Q000737:chemistry; D010084:Oxidation-Reduction
D007094:Imides; D010080:Oxazoles; D016877:Oxidants; D002563:Cerium; C004653:ceric ammonium nitrate