title: Management of acute bleeding in a patient with congenital afibrinogenaemia.
abstract: Congenital afibrinogenaemia is a rare bleeding disorder characterized by absence of fibrinogen and varying bleeding tendency. Treatment with fibrinogen concentrates is considered to be the best choice for afibrinogenaemic patients who experience bleeding. We report the case of a 22-year-old Greek patient who presented with large muscular haematomas and was treated with fibrinogen concentrates. The efficacy of this treatment and the problems that arose during his hospitalization are being discussed.
authors.affiliation: Haematology Section of Second Propedeutic, Department of Internal Medicine, Aristotle University of Thessaloniki, Hippokration Hospital, Thessaloniki, Greece. ktziomalos@yahoo.com
authors.forename: S
authors.initials: S
authors.lastname: Vakalopoulou
authors.forename: D
authors.initials: D
authors.lastname: Rizopoulou
authors.forename: E
authors.initials: E
authors.lastname: Zafiriadou
authors.forename: V
authors.initials: V
authors.lastname: Perifanis
authors.forename: K
authors.initials: K
authors.lastname: Tziomalos
authors.forename: E
authors.initials: E
authors.lastname: Lefkou
authors.forename: M
authors.initials: M
authors.lastname: Hill
authors.forename: G
authors.initials: G
authors.lastname: Dolan
authors.forename: V
authors.initials: V
authors.lastname: Garipidou
mesh_terms: D000328:Adult; D000347:Afibrinogenemia / Q000150:complications*; D001778:Blood Coagulation Disorders; D005340:Fibrinogen / Q000627:therapeutic use*; D006470:Hemorrhage / Q000209:etiology* / Q000517:prevention & control; D006801:Humans; D008297:Male; D035583:Rare Diseases
chemical_list: D005340:Fibrinogen