title: Total synthesis of (+/-)-morphine.
abstract: [Structure: see text] The morphinan skeleton was effectively synthesized by an intramolecular Mannich-type reaction. Further transformation led to total synthesis of morphine.
authors.affiliation: Graduate School of Pharmaceutical Sciences, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.
authors.forename: Kenji
authors.initials: K
authors.lastname: Uchida
authors.forename: Satoshi
authors.initials: S
authors.lastname: Yokoshima
authors.forename: Toshiyuki
authors.initials: T
authors.lastname: Kan
authors.forename: Tohru
authors.initials: T
authors.lastname: Fukuyama
mesh_terms: D015394:Molecular Structure; D009020:Morphine / Q000138:chemical synthesis*
chemical_list: D009020:Morphine