title: Reproducibility and responsiveness of the Symptom Severity Scale and the hand and finger function subscale of the Dutch arthritis impact measurement scales (Dutch-AIMS2-HFF) in primary care patients with wrist or hand problems.
abstract: BACKGROUND
  To determine the clinimetric properties of two questionnaires assessing symptoms (Symptom Severity Scale) and physical functioning (hand and finger function subscale of the AIMS2) in a Dutch primary care population.
  
  
  METHODS
  The first 84 participants in a 1-year follow-up study on the diagnosis and prognosis of hand and wrist problems completed the Symptom Severity Scale and the hand and finger function subscale of the Dutch-AIMS2 twice within 1 to 2 weeks. The data were used to assess test-retest reliability (ICC) and smallest detectable change (SDC, based on the standard error of measurement (SEM)). To assess responsiveness, changes in scores between baseline and the 3 month follow-up were related to an external criterion to estimate the minimal important change (MIC). We calculated the group size needed to detect the MIC beyond measurement error.
  
  
  RESULTS
  The ICC for the Symptom Severity Scale was 0.68 (95% CI: 0.54-0.78). The SDC was 1.00 at individual level and 0.11 at group level, both on a 5-point scale. The MIC was 0.23, exceeding the SDC at group level. The group size required to detect a MIC beyond measurement error was 19 for the Symptom Severity Scale. The ICC for the hand and finger function subscale of the Dutch-AIMS2 was 0.62 (95% CI: 0.47-0.74). The SDC was 3.80 at individual level and 0.42 at group level, both on an 11-point scale. The MIC was 0.31, which was less than the SDC at group level. The group size required to detect a MIC beyond measurement error was 150.
  
  
  CONCLUSIONS
  In our heterogeneous primary care population the Symptom Severity Scale was found to be a suitable instrument to assess the severity of symptoms, whereas the hand and finger function subscale of the Dutch-AIMS2 was less suitable for the measurement of physical functioning in patients with hand and wrist problems.
authors.affiliation: Department of General Practice, VU University Medical Center, Amsterdam, The Netherlands. mn.spies@vumc.nl
authors.forename: Marinda N
authors.initials: MN
authors.lastname: Spies-Dorgelo
authors.forename: Caroline B
authors.initials: CB
authors.lastname: Terwee
authors.forename: Wim A B
authors.initials: WA
authors.lastname: Stalman
authors.forename: Daniëlle A W M
authors.initials: DA
authors.lastname: van der Windt
mesh_terms: D000203:Activities of Daily Living; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001168:Arthritis / Q000503:physiopathology* / Q000523:psychology; D005260:Female; D005385:Fingers / Q000473:pathology; D006225:Hand / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009426:Netherlands; D010147:Pain Measurement; D011320:Primary Health Care; D011594:Psychometrics / Q000295:instrumentation*; D011788:Quality of Life; D012720:Severity of Illness Index; D018434:Sickness Impact Profile; D011795:Surveys and Questionnaires