title: Bacteriology of granulation tissue in laryngotracheal stenosis patients.
abstract: BACKGROUND
  The formation of granulation tissue is an important factor promoting recurrence after surgical treatment of laryngotracheal stenosis. Bacterial infection was claimed to be the cause.
  
  
  OBJECTIVE
  The present study aimed to identify the bacteriology of granulation tissue in laryngotracheal stenosis patients.
  
  
  METHODS
  Data was collected prospectively. Granulation tissue found in the site of laryngotracheal stenosis was removed and sent to the microbiologic study to identify the organisms.
  
  
  RESULTS
  Twenty-four specimens from 17 patients were included in the present study. Coagulase-positive Staphylococcus (45.8%) was the most common gram-positive organism and Pseudomonas aeruginosa as well as Enterobacter species (16.7%) were the most common gram-negative bacteria. Ciprofloxacin may be the oral antibiotic that should be recommended.
  
  
  CONCLUSIONS
  Coagulase-positive Staphylococcus, Pseudomonas aeruginosa as well as Enterobacter species were the common organisms identified from the granulation tissue in recurrent laryngotracheal stenosis. Oral antibiotics, such as ciprofloxacin, may have benefit in reducing the formation of this granulation tissue.
authors.affiliation: Department of Otolaryngology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand. wisree@gmail.com
authors.forename: Wisoot
authors.initials: W
authors.lastname: Reechaipichitkul
authors.forename: Surasakdi
authors.initials: S
authors.lastname: Wongratanacheewin
authors.forename: Teeraporn
authors.initials: T
authors.lastname: Ratanaanekchai
authors.forename: Surapol
authors.initials: S
authors.lastname: Suetrong
authors.forename: Suwanna
authors.initials: S
authors.lastname: Nonthapa
mesh_terms: D000293:Adolescent; D000328:Adult; D001419:Bacteria / Q000302:isolation & purification; D002648:Child; D005260:Female; D006097:Granulation Tissue / Q000382:microbiology*; D006801:Humans; D007829:Laryngostenosis / Q000382:microbiology* / Q000517:prevention & control / Q000601:surgery; D007830:Larynx / Q000382:microbiology; D008297:Male; D008875:Middle Aged; D014132:Trachea / Q000382:microbiology