title: Influence of epicardial adipose tissue and adipocytokine levels on cardiac abnormalities in visceral obesity.
abstract: Adipocytokine levels and visceral adipose tissue (VAT) seem to be associated with some cardiac abnormalities and a role of visceral fat in predisposing to cardiac dysfunction, possibly through a low-grade state of inflammation, has been demonstrated. In this study we firstly show that elevated levels of both monocyte chemoattractant protein 1 (MCP-1) and soluble IL-6 receptor/interleukin-6 (sIL-6R/IL-6) complex are closely correlated with epicardial fat thickness.
authors.forename: Alexis E
authors.initials: AE
authors.lastname: Malavazos
authors.forename: Federica
authors.initials: F
authors.lastname: Ermetici
authors.forename: Calin
authors.initials: C
authors.lastname: Coman
authors.forename: Massimiliano M
authors.initials: MM
authors.lastname: Corsi
authors.forename: Lelio
authors.initials: L
authors.lastname: Morricone
authors.forename: Bruno
authors.initials: B
authors.lastname: Ambrosi
mesh_terms: D000273:Adipose Tissue / Q000000981:diagnostic imaging*; D000328:Adult; D016022:Case-Control Studies; D018932:Chemokine CCL2 / Q000097:blood*; D005260:Female; D006346:Heart Septum / Q000000981:diagnostic imaging; D006352:Heart Ventricles / Q000000981:diagnostic imaging; D006801:Humans; D015850:Interleukin-6 / Q000097:blood*; D009765:Obesity / Q000150:complications*; D010496:Pericardium / Q000000981:diagnostic imaging*; D019947:Receptors, Interleukin-6 / Q000097:blood*; D012044:Regression Analysis; D014463:Ultrasonography
chemical_list: D018932:Chemokine CCL2; D015850:Interleukin-6; D019947:Receptors, Interleukin-6