Short telomeres: cause or consequence of aging?
Questions about mechanisms, about the direction of causality, and about cellular heterogeneity complicate interpretation of claims associating short telomeres with adverse health outcomes.
Hornsby
Peter J
PJ
Department of Physiology, University of Texas Health Science Center at San Antonio, San Antonio, TX 78245, USA. hornsby@uthscsa.edu
D000375:Aging / Q000235:genetics* / Q000276:immunology; D000818:Animals; D016922:Cellular Senescence / Q000235:genetics* / Q000276:immunology; D006801:Humans; D007113:Immunity, Innate / Q000235:genetics* / Q000276:immunology; D007962:Leukocytes / Q000276:immunology; D008136:Longevity / Q000235:genetics* / Q000276:immunology; D011598:Psychoneuroimmunology / Q000639:trends; D012923:Social Class; D013315:Stress, Psychological / Q000235:genetics* / Q000276:immunology; D016615:Telomere / Q000235:genetics* / Q000276:immunology