Surrounding ipsilateral eruptive seborrheic keratosis as a warning sign of intraductal breast carcinoma and Paget's disease (Leser Trelat sign).
Paget disease of the breast, most often occurs in middle-aged women. Leser-Trelat sign is a rare cutaneous manifestation of internal malignancy that is usually associated with visceral-type adenocarcinoma. We report a patient with Paget disease of the nipple and intraductal carcinoma who presented with ipsilateral, eruptive grouped seborrheic keratoses of the areola and nipple of the breast.
Shamsadini
Sadollah
S
Wadji
Masood Baghaei
MB
Shamsadini
Ayeh
A
D001941:Breast Diseases / Q000209:etiology*; D001943:Breast Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D005260:Female; D006801:Humans; D017492:Keratosis, Seborrheic / Q000209:etiology*; D008875:Middle Aged; D009558:Nipples; D010144:Paget's Disease, Mammary / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D010257:Paraneoplastic Syndromes / Q000209:etiology*