title: Comparison study of laboratory and production spray guns in film coating: effect of pattern air and nozzle diameter.
abstract: An optimal atomization air/pattern air ratio is necessary for a good coating process. The influences of variations in pattern air and nozzle diameter on the spray characteristics, such as droplet size, droplet velocity, and spray density, are investigated by using laboratory and production Schlick spray guns, both equipped with a new antibearding cap (ABC). An increase in the pattern air results in a wider spray accompanied with a decrease in droplet size in the spray center for both spray guns. Furthermore, an increase in the pattern air leads to a reduction in spray density in the spray center and, simultaneously, to an increase in spray density at the spray rim. A variation in nozzle diameter does not influence the spray characteristics for both spray guns.
authors.affiliation: Institute of Pharmaceutics and Biopharmaceutics, Heinrich-Heine-University, Duesseldorf, Germany.
authors.forename: Ronny
authors.initials: R
authors.lastname: Müller
authors.forename: Peter
authors.initials: P
authors.lastname: Kleinebudde
mesh_terms: D002626:Chemistry, Pharmaceutical / Q000295:instrumentation* / Q000379:methods; D020099:Coated Materials, Biocompatible / Q000138:chemical synthesis*; D007753:Laboratories; D013678:Technology, Pharmaceutical / Q000295:instrumentation* / Q000379:methods
chemical_list: D020099:Coated Materials, Biocompatible