title: [Biological mechanisms of aging].
abstract: Contemporary views on the mechanisms of aging and aging variations--progeria and longevity are presented. Replicative aging, the roles of glycation and free radicals on the genetical determination of progeria and longevity are discussed.
authors.affiliation: Ustav biologie a lékarské genetiky 1 LF UK a VFN, Praha. boto@lf1.cuni.cz
authors.forename: B
authors.initials: B
authors.lastname: Otová
authors.forename: Z
authors.initials: Z
authors.lastname: Kalvach
authors.forename: M
authors.initials: M
authors.lastname: Snejdrlová
mesh_terms: D000375:Aging / Q000502:physiology*; D000975:Antioxidants / Q000378:metabolism; D017209:Apoptosis; D002118:Calcium / Q000378:metabolism; D002453:Cell Cycle; D002455:Cell Division; D005609:Free Radicals / Q000378:metabolism; D005947:Glucose / Q000378:metabolism; D006801:Humans; D015227:Lipid Peroxidation; D008136:Longevity / Q000235:genetics; D009154:Mutation; D011371:Progeria / Q000503:physiopathology; D016615:Telomere / Q000235:genetics
chemical_list: D000975:Antioxidants; D005609:Free Radicals; D005947:Glucose; D002118:Calcium