title: Antisepsis.
abstract: All dialysis treatments include a certain risk of infection because of the decreased immune defenses of the patients and because of dialytic techniques that increase the potential of microbial contamination. Peritoneal dialysis, and in particular continuous ambulatory peritoneal dialysis (CAPD), has a higher risk of infections of the peritoneum, but even of the subcutaneous tunnel. These infections are caused by environmental microorganisms principally gram-positives (Staphylococcus epidermidis and Staphylococcus aureus). We tested three active ingredients, electrolytic chloroxidizer, iodine and chlorhexidine gluconate. It is evident that because of the large spectrum of activity, the good effectiveness even at the lowest concentration, coupled with good tolerability (and to the fact of not causing allergic reactions) the electrolytic chloroxidizer appears to be an ideal antiseptic in CAPD.
authors.affiliation: Ospedale S. Maria Della Misericordia Hospital, Perugia, Italy.
authors.forename: Paolo
authors.initials: P
authors.lastname: Bianchi
authors.forename: Emanuela
authors.initials: E
authors.lastname: Buoncristiani
authors.forename: Umberto
authors.initials: U
authors.lastname: Buoncristiani
mesh_terms: D000891:Anti-Infective Agents, Local / Q000008:administration & dosage* / Q000009:adverse effects; D001424:Bacterial Infections / Q000453:epidemiology / Q000517:prevention & control*; D004866:Equipment Contamination / Q000517:prevention & control; D006801:Humans; D006967:Hypersensitivity / Q000453:epidemiology; D006997:Hypochlorous Acid / Q000008:administration & dosage* / Q000009:adverse effects; D010531:Peritoneal Dialysis, Continuous Ambulatory / Q000009:adverse effects / Q000379:methods* / Q000706:statistics & numerical data; D010538:Peritonitis / Q000453:epidemiology / Q000517:prevention & control*; D012307:Risk Factors; D012965:Sodium Chloride / Q000008:administration & dosage* / Q000009:adverse effects
chemical_list: C057052:Amuchina; D000891:Anti-Infective Agents, Local; D012965:Sodium Chloride; D006997:Hypochlorous Acid