title: Is cardiac surgery warranted in children with Down syndrome? A case-controlled review.
abstract: OBJECTIVE
  To compare children with Down syndrome and children without Down syndrome and investigate whether there is a significant difference in the burden that is placed on the health care system between these two groups only in respect of the repair of congenital heart disease at Red Cross War Memorial Children's Hospital, Cape Town, South Africa.
  
  
  METHODS
  This study is a retrospective case control review.
  
  
  METHODS
  Red Cross War Memorial Children's Hospital, Cape Town, South Africa.
  
  
  METHODS
  The sample group of 50 Down syndrome children who had received cardiac surgery between January 1998 and June 2003 was compared with a control group of 50 nonsyndromic children who had received cardiac surgery during the same period.
  
  
  METHODS
  Sex and diagnoses (cardiac and noncardiac), number of days spent in hospital and in ICU, complication rates, re-operation rates, early mortality rates, planned further cardiac surgery. Costs of these outcomes were not quantified in exact monetary terms.
  
  
  RESULTS
  There was no significant difference between the two groups in terms of the burden that was placed on the health care system. Similar complication rates, re-operation rates and early mortality rates were recorded for both groups. The Down syndrome group appeared to benefit more from cardiac surgery than the non-Down syndrome group.
  
  
  CONCLUSIONS
  Denying cardiac surgery to children with Down syndrome does not improve the efficiency of resource allocation. It is therefore not reasonable to suggest that the problem of scarce resources can be ameliorated by discriminating against children with Down syndrome.
authors.affiliation: Division of Critical Care and Children's Heart Diseases, School of Child and Adolescent Health, University of Cape Town and Red Cross War Memorial Children's Hospital, Rondebosch, Cape Town, South Africa.
authors.forename: M A
authors.initials: MA
authors.lastname: Roussot
authors.forename: J B
authors.initials: JB
authors.lastname: Lawrenson
authors.forename: J
authors.initials: J
authors.lastname: Hewitson
authors.forename: R
authors.initials: R
authors.lastname: Smart
authors.forename: H P
authors.initials: HP
authors.lastname: De Decker
mesh_terms: D006348:Cardiac Surgical Procedures / Q000706:statistics & numerical data*; D002675:Child, Preschool; D003695:Delivery of Health Care / Q000592:standards*; D004314:Down Syndrome / Q000150:complications*; D005260:Female; D005500:Follow-Up Studies; D006301:Health Services Needs and Demand; D006330:Heart Defects, Congenital / Q000150:complications / Q000453:epidemiology / Q000601:surgery*; D006801:Humans; D007223:Infant; D008297:Male; D015995:Prevalence; D012189:Retrospective Studies; D013019:South Africa / Q000453:epidemiology; D016896:Treatment Outcome