title: Cine magnetic resonance imaging of the small bowel: comparison of different oral contrast media.
abstract: OBJECTIVE
  To evaluate several substances regarding small bowel distension and contrast on balanced steady-state free precession (bSSFP) cine magnetic resonance (MR) images.
  
  
  METHODS
  Luminal contrast was evaluated in 24 volunteers after oral application of two different contrast agent groups leading to either bright lumen (pineapple, blueberry juice) or dark lumen (tap water, orange juice) on T1-weighted images. Bowel distension was evaluated in 30 patients ingesting either methylcellulose or mannitol solution for limiting intestinal absorption. Fifteen patients with duodeno-jejunal intubation served as the control. Quantitative evaluation included measurement of luminal signal intensities and diameters of four bowel segments, qualitative evaluation assessed luminal contrast and distension on a five-point scale.
  
  
  RESULTS
  Quantitative and qualitative evaluation of the four contrast agents revealed no significant differences regarding luminal contrast on bSSFP images. Quantitative evaluation revealed significantly lower (P<0.05) small bowel distension for three out of four segments (qualitative evaluation: two out of four segments) for methylcellulose in comparison to the control. Mannitol was found to be equal to the control.
  
  
  CONCLUSIONS
  Oral ingestion of tap water or orange juice in combination with mannitol is recommended for cine MR imaging of the small bowel regarding luminal contrast and small bowel distension on bSSFP sequences.
authors.affiliation: Department of Radiology, Charité - Universitätsmedizin Berlin, Charité Campus Mitte, Berlin, Germany. patrick.asbach@charite.de
authors.forename: P
authors.initials: P
authors.lastname: Asbach
authors.forename: C
authors.initials: C
authors.lastname: Breitwieser
authors.forename: G
authors.initials: G
authors.lastname: Diederichs
authors.forename: S
authors.initials: S
authors.lastname: Eisele
authors.forename: D
authors.initials: D
authors.lastname: Kivelitz
authors.forename: M
authors.initials: M
authors.lastname: Taupitz
authors.forename: M
authors.initials: M
authors.lastname: Zeitz
authors.forename: B
authors.initials: B
authors.lastname: Hamm
authors.forename: C
authors.initials: C
authors.lastname: Klessen
mesh_terms: D000284:Administration, Oral; D000293:Adolescent; D000328:Adult; D000368:Aged; D003287:Contrast Media / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D007421:Intestine, Small / Q000473:pathology*; D019028:Magnetic Resonance Imaging, Cine / Q000379:methods; D008297:Male; D008875:Middle Aged
chemical_list: D003287:Contrast Media