title: Treatment of cutaneous infection by Alternaria alternata with voriconazole in a liver transplant patient.
abstract: Alternaria alternata is a dematiaceous mold capable of causing systemic and dermatological infections in immunosuppressed patients. We present a case of a liver transplant patient with cutaneous alternariosis and no response to amphotericin B lipid or surgical debridement of the lesions. Treatment with intravenous voriconazole was initiated, followed by the oral protocol, with complete resolution of the lesions. Voriconazole is an efficient alternative for the treatment of cutaneous lesions produced by A alternata.
authors.affiliation: Hospital Clínico Universitario Lozano Blesa, Zaragoza, Spain.
authors.forename: P
authors.initials: P
authors.lastname: Luque
authors.forename: F A
authors.initials: FA
authors.lastname: García-Gil
authors.forename: J
authors.initials: J
authors.lastname: Larraga
authors.forename: B
authors.initials: B
authors.lastname: Jiménez
authors.forename: E
authors.initials: E
authors.lastname: Tomé-Zelaya
authors.forename: M T
authors.initials: MT
authors.lastname: Serrano
authors.forename: M E
authors.initials: ME
authors.lastname: Barrao
mesh_terms: D000528:Alternaria; D000935:Antifungal Agents / Q000627:therapeutic use*; D003881:Dermatomycoses / Q000175:diagnosis*; D017809:Fatal Outcome; D006801:Humans; D016031:Liver Transplantation; D008875:Middle Aged; D009181:Mycoses / Q000188:drug therapy*; D011183:Postoperative Complications / Q000188:drug therapy / Q000382:microbiology; D011743:Pyrimidines / Q000627:therapeutic use*; D012867:Skin / Q000382:microbiology; D014230:Triazoles / Q000627:therapeutic use*; D065819:Voriconazole
chemical_list: D000935:Antifungal Agents; D011743:Pyrimidines; D014230:Triazoles; D065819:Voriconazole