title: Levels of vascular cell adhesion molecule-1 and endothelin-1 in ischemic stroke: a longitudinal prospective study.
abstract: OBJECTIVE
  To determine levels of vascular cellular adhesion molecule (VCAM)-1 and endothelin (ET)-1 in patients with stroke.
  
  
  METHODS
  Thirty-four patients were prospectively studied. Plasma levels of VCAM-1 and ET-1 were measured by ELISA within 72 h of the event, at 7 and 90 days.
  
  
  RESULTS
  Levels of VCAM-1 increased overtime, whereas ET-1 values were initially and persistently elevated.
  
  
  CONCLUSIONS
  Increased circulating levels of VCAM-1 and ET-1 are present during stroke.
authors.affiliation: Division of Neurology, Hospital de Clínicas de Porto Alegre, Graduate Program in Clinical Medicine, Universidade Federal do Rio Grande do Sul, RS, Brazil.
authors.forename: Rosane
authors.initials: R
authors.lastname: Brondani
authors.forename: Carlos R M
authors.initials: CR
authors.lastname: Rieder
authors.forename: Denise
authors.initials: D
authors.lastname: Valente
authors.forename: Luis F
authors.initials: LF
authors.lastname: Araújo
authors.forename: Nadine
authors.initials: N
authors.lastname: Clausell
mesh_terms: D000368:Aged; D015415:Biomarkers / Q000097:blood; D002545:Brain Ischemia / Q000150:complications*; D019332:Endothelin-1 / Q000097:blood*; D005260:Female; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D020521:Stroke / Q000175:diagnosis* / Q000209:etiology; D019010:Vascular Cell Adhesion Molecule-1 / Q000097:blood*
chemical_list: D015415:Biomarkers; D019332:Endothelin-1; D019010:Vascular Cell Adhesion Molecule-1