A novel approach to functionalised pyridazinone arrays.
A series of 3,6-dichloro-1H-pyridazin-4-ones have been prepared via the cycloaddition of 3,6-dichlorotetrazine with alkynylboronates, and their employment as useful synthetic intermediates was highlighted through a selection of highly regioselective C-O, C-S and C-C bond forming reactions.
Helm
Matthew D
MD
Department of Chemistry, University of Sheffield, Brook Hill, Sheffield, UK S3 7HF.
Plant
Andrew
A
Harrity
Joseph P A
JP
D001897:Boronic Acids / Q000737:chemistry; D011724:Pyridazines / Q000138:chemical synthesis*
D001897:Boronic Acids; D011724:Pyridazines