Cucurbitacin B 2-sulfate and cucurbitacin glucosides from the root bark of Helicteres angustifolia.
A new sulfated cucurbitacin, cucurbitacin B 2-sulfate (1) and a new cucurbitacin glucoside, cucurbitacin G 2-O-beta-D-glucopyranoside (2) together with two known cucurbitacin glucosides, arvenin I and arvenin III were isolated from the root bark of Helicteres angustifolia. The structures of these compounds were established on the basis of spectroscopic and chemical evidence. These four compounds taste of strong bitterness. Compound 1 is a first sulfated cucurbitacin found in plants.
Chen
Zong-Tsi
ZT
Department of Applied Chemistry, Chia-Nan University of Pharmacy and Science, Taiwan, ROC. ztc19530612@mail.chna.edu.tw
Lee
Shwu-Woan
SW
Chen
Chiu-Ming
CM
D005960:Glucosides / Q000737:chemistry* / Q000302:isolation & purification; D009682:Magnetic Resonance Spectroscopy / Q000379:methods / Q000592:standards; D019660:Malvaceae / Q000737:chemistry*; D008968:Molecular Conformation; D018517:Plant Roots / Q000737:chemistry*; D012015:Reference Standards; D013045:Species Specificity; D013237:Stereoisomerism; D014315:Triterpenes / Q000737:chemistry* / Q000302:isolation & purification
D005960:Glucosides; D014315:Triterpenes; C516764:cucurbitacin G 2-O-beta-D-glucopyranoside; C041246:cucurbitacin B