title: Assessment of self-monitoring of blood pressure in the diagnosis of isolated clinic hypertension.
abstract: BACKGROUND
  There are no studies assessing cardiovascular morbidity, morality in patients with isolated clinical hypertension (ICH) with self-blood pressure monitoring (SBPM).
  
  
  OBJECTIVE
  To determine the value of SBPM in the diagnosis of ICH.
  
  
  METHODS
  Cohort study. New hypertensive and normotensive patients 15-75 years, without cardiovascular events history.
  
  
  METHODS
  Oriented anamnesis hypertension; blood pressure measurements (BP): clinical BP, SBPM and ambulatory BP monitoring (ABPM); evaluation of target organ damage (TOD); electrocardiogram; retinography and microalbuminuria (MA).
  
  
  RESULTS
  One hundred and thirty-five patients, 95 hypertensive (62.1% males; mean age 59.08+/-16.8 years), 40 normotensive (37.5% males; mean are 56.32+/-10.22 years). BP measurements (mmHG) in normotensives vs hypertensives: clinical BP, 125.36/76.74 vs 149.81/87.86 mmHg (p<0.0001) and SPPM, 114.90/69.96 vs 142.06/86.31 (p<0.0001). Twenty-four-hour ABPM: 135.41/81/81.74. Prevalence of TOD in hypertensive: 23.10% left ventricular hypertrophy (LVH), sustained hypertension (SH): clinic BP, 149.88/86.34 vs 152.51/89.55 (p>0.10); SBPM: 147.895/88.95 vs 128.17/79 (p<0.0001) and ABPM, 141.72/88.22 vs 131.66/80 (p=0.053 for systolic). TOD in SH vs ICH: LVH, 24.6% vs 19.2% (p=0.814); exudates or haemorrhages, 7.7% vs 9.8% (p=0.580). The risk of an occurrence of any TOD in ICH patients is lower for 125/80 (OR=2.5).
  
  
  CONCLUSIONS
  VAMPAHICA will provide information about value SBPM in the diagnosis of ICH. Advanced retinopathy is relative frequent in ICH patients. If TOD is accepted as a surrogate endpoint, the diagnostic values of ICH will be probably decreased.
authors.affiliation: Basic Health Area Anglès, Institut d'Assistència Sanitària, Spain. gcolld@meditex.es
authors.forename: Gabriel Coll
authors.initials: GC
authors.lastname: de Tuero
authors.forename: Quintí Foguet
authors.initials: QF
authors.lastname: Boreu
authors.forename: Antonio
authors.initials: A
authors.lastname: Rodríguez-Poncelas
authors.forename: Ramon
authors.initials: R
authors.lastname: Creus
authors.forename: Maria
authors.initials: M
authors.lastname: Sanmartín
authors.forename: Narcis
authors.initials: N
authors.lastname: Salleras
authors.forename: Marc
authors.initials: M
authors.lastname: Saez
authors.forename: Maria Antònia
authors.initials: MA
authors.lastname: Barceló
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000419:Albuminuria; D018660:Blood Pressure Monitoring, Ambulatory / Q000009:adverse effects / Q000379:methods*; D015331:Cohort Studies; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000175:diagnosis* / Q000401:mortality; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D012164:Retinal Diseases / Q000209:etiology