title: Acremonium mycetoma in a heart transplant recipient.
abstract: Mycetomas are chronic, progressive infections caused either by fungi (eumycetoma) or filamentous bacteria (actinomycetoma) and are characterized by the triad of draining sinuses, tumefaction, and the presence of macroscopic grains. We describe a case of eumycetoma in a cardiac transplant recipient caused by the soil saprophyte Acremonium species. This represents only the fifth case of eumycetoma reported in a solid organ transplant recipient. With the population of immunosuppressed patients and the incidence of invasive fungal infections increasing, consideration should be given to unusual saprophytic fungal infections as emerging opportunistic pathogens.
authors.affiliation: Department of Dermatology, College of Physicians and Surgeons, Columbia University, New York, New York, USA.
authors.forename: Adam S
authors.initials: AS
authors.lastname: Geyer
authors.forename: Lindy P
authors.initials: LP
authors.lastname: Fox
authors.forename: Sameera
authors.initials: S
authors.lastname: Husain
authors.forename: Phyllis
authors.initials: P
authors.lastname: Della-Latta
authors.forename: Marc E
authors.initials: ME
authors.lastname: Grossman
mesh_terms: D000164:Acremonium / Q000302:isolation & purification*; D000935:Antifungal Agents / Q000627:therapeutic use; D002311:Cardiomyopathy, Dilated / Q000601:surgery; D005533:Foot Dermatoses / Q000188:drug therapy / Q000209:etiology* / Q000382:microbiology; D005714:Gambia / Q000208:ethnology; D016027:Heart Transplantation; D006801:Humans; D016867:Immunocompromised Host; D007166:Immunosuppressive Agents / Q000009:adverse effects; D017964:Itraconazole / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D008271:Mycetoma / Q000188:drug therapy / Q000209:etiology*; D011183:Postoperative Complications / Q000188:drug therapy / Q000209:etiology* / Q000382:microbiology
chemical_list: D000935:Antifungal Agents; D007166:Immunosuppressive Agents; D017964:Itraconazole