title: [Psychotic symptoms in a case of locked-in syndrome].
abstract: In this case report we describe a patient who suffered brainstem bleeding mainly in the pons and mesencephalon leading to locked-in syndrome. During rehabilitation she suffered psychotic symptoms of threatening character. Due to location of the lesion and the coincidental appearance of the bleeding, we diagnosed an organic psychosis. After treatment with the atypical neuroleptic drug Quetiapine, the symptoms decreased, facilitating the patient's rehabilitation course.
authors.affiliation: Kliniken Schmieder, Am Tafelholz 8, 78476 Allenbach, Germany. jochen_mutschler@web.de
authors.forename: J
authors.initials: J
authors.lastname: Mutschler
authors.forename: D
authors.initials: D
authors.lastname: Czell
authors.forename: M
authors.initials: M
authors.lastname: Kaps
authors.forename: G
authors.initials: G
authors.lastname: Manzl
mesh_terms: D000929:Antidepressive Agents, Tricyclic / Q000627:therapeutic use; D014150:Antipsychotic Agents / Q000627:therapeutic use; D001933:Brain Stem / Q000473:pathology; D002543:Cerebral Hemorrhage / Q000150:complications*; D003702:Delusions / Q000175:diagnosis*; D003866:Depressive Disorder / Q000175:diagnosis / Q000188:drug therapy; D003987:Dibenzothiazepines / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications*; D008803:Mianserin / Q000031:analogs & derivatives / Q000627:therapeutic use; D008875:Middle Aged; D000078785:Mirtazapine; D009460:Neurologic Examination; D011618:Psychotic Disorders / Q000175:diagnosis* / Q000188:drug therapy; D011782:Quadriplegia / Q000175:diagnosis* / Q000188:drug therapy; D000069348:Quetiapine Fumarate; D014057:Tomography, X-Ray Computed
chemical_list: D000929:Antidepressive Agents, Tricyclic; D014150:Antipsychotic Agents; D003987:Dibenzothiazepines; D008803:Mianserin; D000069348:Quetiapine Fumarate; D000078785:Mirtazapine