A review of inherited platelet disorders with guidelines for their management on behalf of the UKHCDO.
The inherited platelet disorders are an uncommon cause of symptomatic bleeding. They may be difficult to diagnose (and are likely to be under-diagnosed) and pose problems in management. This review discusses the inherited platelet disorders summarising the current state of the art with respect to investigation and diagnosis and suggests how to manage bleeding manifestations with particular attention to surgical interventions and the management of pregnancy.
Bolton-Maggs
Paula H B
PH
Department of Haematology, Manchester Royal Infirmary, Manchester, UK. paula.bolton-maggs@manchester.ac.uk
Chalmers
Elizabeth A
EA
Collins
Peter W
PW
Harrison
Paul
P
Kitchen
Stephen
S
Liesner
Ri J
RJ
Minford
Adrian
A
Mumford
Andrew D
AD
Parapia
Liakat A
LA
Perry
David J
DJ
Watson
Steve P
SP
Wilde
Jonathan T
JT
Williams
Michael D
MD
D025861:Blood Coagulation Disorders, Inherited / Q000175:diagnosis / Q000628:therapy; D001791:Blood Platelet Disorders / Q000175:diagnosis / Q000628:therapy; D001792:Blood Platelets / Q000502:physiology; D005260:Female; D006402:Hematologic Diseases / Q000175:diagnosis* / Q000628:therapy; D006474:Hemorrhagic Disorders / Q000175:diagnosis / Q000628:therapy; D006801:Humans; D007231:Infant, Newborn; D011247:Pregnancy