Cerebrovascular disease basis of depression: post-stroke depression and vascular depression.
The close association between cerebrovascular disease and depression has been known for more than a century, yet much of the progress in understanding the cerebrovascular basis of depression in late life has been spurred by development of two concepts: 'post-stroke depression' and 'vascular depression'. The purpose of this review is to examine the epidemiology, diagnostic features, course, pathophysiology and prognosis of post-stroke depression and vascular depression, to highlight their common features, and to contrast the distinct aspects of these two subtypes of geriatric depression.
Newberg
Andrew R
AR
Department of Psychiatry, The Johns Hopkins Hospital, Baltimore, USA. newberga@mail.nih.gov
Davydow
Dimitry S
DS
Lee
Hochang B
HB
D000368:Aged; D000375:Aging / Q000523:psychology; D002561:Cerebrovascular Disorders / Q000523:psychology*; D003863:Depression / Q000453:epidemiology / Q000209:etiology* / Q000503:physiopathology; D006801:Humans; D008875:Middle Aged; D015995:Prevalence; D011379:Prognosis; D012307:Risk Factors; D020521:Stroke / Q000523:psychology*