title: Synthesis and fungicidal activity of N-2-(3-methoxy-4-propargyloxy) phenethyl amides. Part 3: stretched and heterocyclic mandelamide oomyceticides.
abstract: Novel analogues of mandipropamid have been designed and prepared. The synthetic approach to these stretched and heterocyclic mandelamides is outlined. Biological data demonstrate their high efficacy against important plant diseases like tomato and potato late blight (Phytophthora infestans De Bary) and grape downy mildew (Plasmopara viticola Berliner & de Toni). Structure-activity relationship studies are discussed.
authors.affiliation: Syngenta AG, Crop Protection Research, Chemistry, Schwarzwaldallee 215, CH-4058 Basel, Switzerland. clemens.lamberth@syngenta.com
authors.forename: Clemens
authors.initials: C
authors.lastname: Lamberth
authors.forename: Hans-Joachim
authors.initials: HJ
authors.lastname: Kempf
authors.forename: Miroslav
authors.initials: M
authors.lastname: Kriz
mesh_terms: D000577:Amides / Q000138:chemical synthesis* / Q000737:chemistry; D005659:Fungicides, Industrial / Q000138:chemical synthesis* / Q000737:chemistry; D008333:Mandelic Acids; D015394:Molecular Structure; D009868:Oomycetes; D010935:Plant Diseases
chemical_list: D000577:Amides; D005659:Fungicides, Industrial; D008333:Mandelic Acids; C010413:mandelamide