title: Achiral, cheap, and potent inhibitors of Plasmepsins I, II, and IV.
authors.affiliation: Drug Discovery, Chemistry and Biology, Actelion Pharmaceuticals Ltd., Gewerbestrasse 16, 4123 Allschwil, Switzerland.
authors.forename: Christoph
authors.initials: C
authors.lastname: Boss
authors.forename: Olivier
authors.initials: O
authors.lastname: Corminboeuf
authors.forename: Corinna
authors.initials: C
authors.lastname: Grisostomi
authors.forename: Solange
authors.initials: S
authors.lastname: Meyer
authors.forename: Andrew F
authors.initials: AF
authors.lastname: Jones
authors.forename: Lars
authors.initials: L
authors.lastname: Prade
authors.forename: Christoph
authors.initials: C
authors.lastname: Binkert
authors.forename: Walter
authors.initials: W
authors.lastname: Fischli
authors.forename: Thomas
authors.initials: T
authors.lastname: Weller
authors.forename: Daniel
authors.initials: D
authors.lastname: Bur
mesh_terms: D000818:Animals; D016282:Aspartic Acid Endopeptidases / Q000037:antagonists & inhibitors*; D001665:Binding Sites; D018360:Crystallography, X-Ray; D008958:Models, Molecular; D015394:Molecular Structure; D010963:Plasmodium falciparum / Q000201:enzymology*; D011480:Protease Inhibitors / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology*; D015800:Protozoan Proteins; D013329:Structure-Activity Relationship
chemical_list: D011480:Protease Inhibitors; D015800:Protozoan Proteins; D016282:Aspartic Acid Endopeptidases; C089643:plasmepsin; C100637:plasmepsin II