title: Radiation therapy for incompletely excised grade II canine mast cell tumors.
abstract: Forty-five dogs with incompletely excised grade II mast cell tumors were treated with radiation using a cobalt 60 teletherapy unit (15 fractions of 3.2 Gy for a total of 48 Gy). Twenty-four of the dogs underwent prophylactic regional lymph node irradiation. Three (6.7%) dogs had tumor recurrence, two (4.4%) dogs developed metastasis, and 14 (31%) dogs developed a second cutaneous mast cell tumor. No difference in overall survival rate was observed between the dogs receiving and not receiving prophylactic irradiation of the regional lymph node.
authors.affiliation: Department of Diagnostic Imaging and Radiation Oncology, Vetsuisse Faculty, University of Zurich, Wintherthurerstrasse 260, Zurich, 8057 Switzerland.
authors.forename: Valerie Jasmine
authors.initials: VJ
authors.lastname: Poirier
authors.forename: William M
authors.initials: WM
authors.lastname: Adams
authors.forename: Lisa J
authors.initials: LJ
authors.lastname: Forrest
authors.forename: Eric M
authors.initials: EM
authors.lastname: Green
authors.forename: Richard R
authors.initials: RR
authors.lastname: Dubielzig
authors.forename: David M
authors.initials: DM
authors.lastname: Vail
mesh_terms: D000818:Animals; D003036:Cobalt Isotopes / Q000627:therapeutic use* / Q000633:toxicity; D004283:Dog Diseases / Q000401:mortality / Q000532:radiotherapy*; D004285:Dogs; D005260:Female; D053208:Kaplan-Meier Estimate; D008198:Lymph Nodes / Q000528:radiation effects; D008207:Lymphatic Metastasis / Q000517:prevention & control; D008297:Male; D034801:Mastocytoma / Q000401:mortality / Q000532:radiotherapy / Q000662:veterinary*; D009364:Neoplasm Recurrence, Local / Q000517:prevention & control / Q000662:veterinary; D011867:Radioisotope Teletherapy / Q000662:veterinary*; D012189:Retrospective Studies; D012720:Severity of Illness Index; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D003036:Cobalt Isotopes