title: Assessment of future remnant liver regeneration after portal vein embolization using three-dimensional CT and MR volumetric analyses.
abstract: The purpose of this study is to portray right portal vein embolization (PVE) as a valuable technique that helps in expanding the volume of the left liver lobe and discuss the relevant published work. We describe our experience with four patients who underwent PVE and analyse the value of CT and MRI in the preoperative evaluation of these patients. Four patients with hepatic malignancy (hepatocellular carcinoma) (n=2) and metastatic liver disease (n=2) underwent portal vein occlusion. PVE was carried out in three patients using polyvinyl alcohol and stainless steel coils. Portal vein ligation was carried out in the fourth patient. In patients who were candidates for right hepatectomy, CT volumetric analysis was carried out before the surgery to assess the total liver volume and the future remnant liver, which is the residual left hepatic volume (in cases of right hepatectomy) or left lateral segment volume (in cases of right tri-segmentectomy). Because the left lobe volumes were insufficient, patients were selected to undergo right PVE. Computed tomography volumetry was carried out 2-4 weeks after embolization to assess left hepatic lobe regeneration. Magnetic resonance volumetric analysis was carried out in two patients before and after embolization. All four patients had significant regeneration of the left lobe and tolerated the surgery with uneventful postoperative recovery.
authors.affiliation: Department of Radiology, Massachusetts General Hospital, Boston, Massachusetts, USA. ttz100@yahoo.com
authors.forename: T T
authors.initials: TT
authors.lastname: Zacharia
mesh_terms: D006528:Carcinoma, Hepatocellular / Q000473:pathology* / Q000628:therapy*; D003131:Combined Modality Therapy; D003287:Contrast Media; D004621:Embolization, Therapeutic; D006498:Hepatectomy; D006801:Humans; D007091:Image Processing, Computer-Assisted; D021621:Imaging, Three-Dimensional; D008113:Liver Neoplasms / Q000473:pathology* / Q000628:therapy; D008115:Liver Regeneration / Q000502:physiology*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D011169:Portal Vein; D012189:Retrospective Studies; D036542:Tomography, Spiral Computed / Q000379:methods*
chemical_list: D003287:Contrast Media