Rational ligand design for metal ion recognition. Synthesis of a N-benzylated N2S3-donor macrocycle for enhanced silver(I) discrimination.
Four previously documented ligand design strategies for achieving Ag(I) discrimination have been applied to the design of a new N-benzylated N2S3-donor macrocycle; the latter shows high selectivity for Ag(I) over Co(II), Ni(II), Cu(II), Zn(II), Cd(II) and Pb(II) in log K and bulk membrane transport studies.
Vasilescu
Ioana M
IM
School of Pharmacy and Molecular Sciences, James Cook University, Townsville, Q. 4811, Australia.
Bray
David J
DJ
Clegg
Jack K
JK
Lindoy
Leonard F
LF
Meehan
George V
GV
Wei
Gang
G
D018360:Crystallography, X-Ray; D008024:Ligands; D008958:Models, Molecular; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D012834:Silver / Q000737:chemistry*; D013237:Stereoisomerism; D013438:Sulfhydryl Compounds / Q000737:chemistry*
D008024:Ligands; D009942:Organometallic Compounds; D013438:Sulfhydryl Compounds; D012834:Silver