Enantioselective phenylacetylene addition to aldehydes and ketones catalyzed by recyclable polymeric Zn(salen) complex.
New polymeric Zn(salen) complex was employed in the enantioselective phenylacetylene addition to aldehydes and ketones to produce corresponding chiral secondary propargylic alcohols with yields (up to 96%) and enantioselectivity (up to 72%) and tertiary propargylic alcohols with yields (up to 79%) and enantioselectivity (up to 68%) at room temperature, with added advantage of four times reuse with retention of enantioselectivity.
Pathak
Kavita
K
Silicates and Catalysis Discipline, Central Salt and Marine Chemicals Research Institute (CSMCRI), Bhavnagar 364 002, Gujarat, India.
Bhatt
Achyut P
AP
Abdi
Sayed H R
SH
Kureshy
Rukhsana I
RI
Khan
Noor-Ul H
NU
Ahmad
Irshad
I
Jasra
Raksh V
RV
D000114:Acetylene / Q000031:analogs & derivatives* / Q000737:chemistry; D000447:Aldehydes / Q000737:chemistry*; D002384:Catalysis; D005029:Ethylenediamines / Q000494:pharmacology*; D007659:Ketones / Q000737:chemistry*; D013237:Stereoisomerism; D013696:Temperature
D000447:Aldehydes; D005029:Ethylenediamines; D007659:Ketones; C044736:phenylacetylene; C011452:disalicylaldehyde ethylenediamine; D000114:Acetylene