title: Older adult medication compliance: integrated review of randomized controlled trials.
abstract: OBJECTIVE
  To examine interventions and outcomes of medication compliance studies in older adults.
  
  
  METHODS
  An integrated review of randomized controlled trials was completed.
  
  
  RESULTS
  Thirty-one of 57 studies reported significantly greater medication compliance in treatment subjects versus control subjects. Interventions included counseling, education, self-medication programs, cues and organizers, and decreasing dosing frequency. Decreasing dosing frequency and self-medication programs were successful, although not frequently evaluated.
  
  
  CONCLUSIONS
  Future studies should address methodologic flaws (eg, small sample sizes, measurement validity issues), test theory-based interventions delivered by diverse providers, evaluate intervention dose, and examine persistence of compliance behavior changes.
authors.affiliation: School of Nursing, University of Missouri-Columbia, Columbia, MO 65211, USA. RussellC@health.missouri.edu
authors.forename: Cynthia L
authors.initials: CL
authors.lastname: Russell
authors.forename: Vicki S
authors.initials: VS
authors.lastname: Conn
authors.forename: Peeranuch
authors.initials: P
authors.lastname: Jantarakupt
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D004358:Drug Therapy; D006801:Humans; D008875:Middle Aged; D010349:Patient Compliance; D016032:Randomized Controlled Trials as Topic