title: Asian ethnicity is associated with reduced pregnancy outcomes after assisted reproductive technology.
abstract: OBJECTIVE
  To determine whether success rates were similar in Asian and Caucasian women undergoing infertility treatment.
  
  
  METHODS
  Secondary data analysis and multivariate modeling.
  
  
  METHODS
  Clinics reporting to the national Society for Assisted Reproductive Technology registry and a university-based clinic.
  
  
  METHODS
  Caucasian and self-identified Asian infertile women undergoing IVF. The study included 25,843 Caucasian and 1,429 Asian patients from the national registry; 370 Caucasian and 197 Asian patients were included from the site-specific clinic.
  
  
  METHODS
  In vitro fertilization.
  
  
  METHODS
  Pregnancy rate and live-birth rate.
  
  
  RESULTS
  Infertile Asian women differed only minimally from their Caucasian counterparts in baseline characteristics and treatment response. Yet Asian women had a decreased clinical pregnancy rate (odds ratio, 0.71; 95% confidence interval 0.64-0.80) and a decreased live-birth rate (odds ratio, 0.69; 95% confidence interval 0.61-0.77). Subsequent multivariate analysis demonstrated that Asian ethnicity was an independent predictor of poor outcome.
  
  
  CONCLUSIONS
  After treatment, infertile Asian women have significantly fewer pregnancies than do Caucasian women. Multivariate analysis indicates that this discrepancy cannot be accounted for by differences in baseline characteristics or by response to current therapeutic interventions.
authors.affiliation: Fertility Physicians of Northern California, San Jose, California, USA. cjpurcell@pol.net <cjpurcell@pol.net>
authors.forename: Karen
authors.initials: K
authors.lastname: Purcell
authors.forename: Michael
authors.initials: M
authors.lastname: Schembri
authors.forename: Linda M
authors.initials: LM
authors.lastname: Frazier
authors.forename: Martha J
authors.initials: MJ
authors.lastname: Rall
authors.forename: Shehua
authors.initials: S
authors.lastname: Shen
authors.forename: Mary
authors.initials: M
authors.lastname: Croughan
authors.forename: David A
authors.initials: DA
authors.lastname: Grainger
authors.forename: Victor Y
authors.initials: VY
authors.lastname: Fujimoto
mesh_terms: D000328:Adult; D001213:Asian / Q000706:statistics & numerical data*; D002140:California / Q000208:ethnology; D005260:Female; D005307:Fertilization in Vitro / Q000706:statistics & numerical data*; D006801:Humans; D007247:Infertility, Female / Q000208:ethnology* / Q000628:therapy*; D011247:Pregnancy; D011256:Pregnancy Outcome / Q000208:ethnology*; D018873:Pregnancy Rate / Q000208:ethnology*; D011379:Prognosis; D018570:Risk Assessment / Q000379:methods; D012307:Risk Factors; D016896:Treatment Outcome; D044465:White People / Q000706:statistics & numerical data*