title: Discontinued drugs in 2005: pulmonary-allergy, dermatological, gastrointestinal and arthritis drugs.
abstract: This perspective is the fourth in a series of papers discussing drugs dropped from development in 2005, focusing on pulmonary-allergy, dermatological, gastrointestinal and arthritis drugs. A survey of discontinued drugs from 2005 is provided, based on data from the Pharmaprojects database, along with an analysis of economic considerations in developing new drugs.
authors.affiliation: School of Pharmacy, Faculty of Medicine, Chinese University of Hong Kong, Shatin, NT, Hong Kong, China. kclee@cuhk.edu.hk
authors.forename: Kenneth K C
authors.initials: KK
authors.lastname: Lee
mesh_terms: D018926:Anti-Allergic Agents; D000893:Anti-Inflammatory Agents; D018501:Antirheumatic Agents; D001168:Arthritis / Q000188:drug therapy; D002986:Clinical Trials as Topic; D003879:Dermatologic Agents; D017277:Drug Approval / Q000191:economics / Q000706:statistics & numerical data; D015195:Drug Design; D004345:Drug Industry / Q000191:economics; D015507:Drugs, Investigational; D005765:Gastrointestinal Agents; D005767:Gastrointestinal Diseases / Q000188:drug therapy; D006801:Humans; D006967:Hypersensitivity / Q000188:drug therapy; D008171:Lung Diseases / Q000188:drug therapy; D012871:Skin Diseases / Q000188:drug therapy
chemical_list: D018926:Anti-Allergic Agents; D000893:Anti-Inflammatory Agents; D018501:Antirheumatic Agents; D003879:Dermatologic Agents; D015507:Drugs, Investigational; D005765:Gastrointestinal Agents