Dental care of patients with autoimmune vesiculobullous diseases: case reports and literature review.
Dental management of patients with autoimmune vesiculobullous disorders is complicated because of prominent involvement of oral mucosa, increased risk of oral disease, and difficulty in rendering dental care. Although these diseases are relatively uncommon, dental practitioners should be familiar with the oral sequelae of these conditions and their management. Pemphigus vulgaris, cicatricial pemphigoid, and epidermolysis bullosa represent the most common autoimmune oral vesiculobullous diseases. This case-illustrated review summarizes the pathogenesis, diagnostic features, and natural history of oral vesiculobullous disorders, placing an emphasis on the treatment and prevention of associated oral disease aimed at maintaining a healthy, functional dentition.
Fatahzadeh
Mahnaz
M
Division of Oral Medicine, Department of Diagnostic Sciences, Room D-855, New Jersey Dental School, 110 Bergen Street, Newark, NJ 07103, USA. fatahza@umdnj.edu
Radfar
Lida
L
Sirois
David A
DA
D000328:Adult; D000368:Aged; D017742:Dental Care for Chronically Ill / Q000379:methods*; D003731:Dental Caries / Q000628:therapy; D003824:Denture, Complete / Q000009:adverse effects; D004037:Diet, Cariogenic; D004820:Epidermolysis Bullosa / Q000150:complications* / Q000188:drug therapy; D006801:Humans; D008297:Male; D008875:Middle Aged; D009059:Mouth Diseases / Q000150:complications*; D009910:Oral Hygiene; D019226:Oral Ulcer / Q000150:complications / Q000188:drug therapy; D010390:Pemphigoid, Benign Mucous Membrane / Q000150:complications* / Q000188:drug therapy; D010392:Pemphigus / Q000150:complications* / Q000188:drug therapy