Case report of a pituitary macroadenoma treated with artemether.
BACKGROUND
This report describes the case of a male patient with pituitary macroadenoma treated with the artemisinin analog artemether.


METHODS
A 75 year-old male patient presented with vision, hearing, and locomotion-related problems. Artemether was administered orally to the patient over a period of 12 months.


RESULTS
Although the tumor remained consistent in size, CT scan shows a reduction in its density, and clinically, the related symptoms and signs resolved significantly as therapy progressed.


CONCLUSIONS
Overall, the artemether treatment was beneficial in improving the patient's quality of life. Artemether and other artemisinin analogs offer promise for cancer therapy.
Singh
Narendra P
NP
Department of Bioengineering, Box 355061, University of Washington, Seattle, WA 98195, USA. narendra@u.washington.edu
Panwar
Vijay Kumar
VK
D000236:Adenoma / Q000000981:diagnostic imaging / Q000188:drug therapy*; D000368:Aged; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D000077549:Artemether; D037621:Artemisinins / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D010911:Pituitary Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy*; D014057:Tomography, X-Ray Computed
D000970:Antineoplastic Agents; D037621:Artemisinins; D000077549:Artemether