title: [Toxicity assessment of the vegetable emulsifier- the aqueous extract from the common soapwort roots].
abstract: Within the limits of experimental observation the assessment of acute and subacute safety of an aqueous extract from Acanthophyllum roots with a solids content of 7%, used as an emulsifier has been manufactured by production of emulsion products. Acute toxicity (LD50) AEAR, probed on mice-male; has allowed to refer to an emulsifier to a class of nontoxic substance. The assessmentof subacute toxicity of an extract (injection in a food allowance within 30 days in a recommended dose--5 ml on 100 g of a standard food allowance) was spent on laboratory rats. Extent of toxicity of a specimen judged on the general state of animals, a body mass dynamics, internals masses, to biochemical parameters of blood plasma, parameters of a peripheric blood, a morphological pattern of an internals. Comparative analysis of results allows to expel toxic effect AEAR in the recommended dose on an organism of animals.
authors.forename: T P
authors.initials: TP
authors.lastname: Iudina
authors.forename: E I
authors.initials: EI
authors.lastname: Tsybul'ko
authors.forename: E I
authors.initials: EI
authors.lastname: Cherevan
authors.forename: Iu V
authors.initials: IuV
authors.lastname: Babin
authors.forename: A V
authors.initials: AV
authors.lastname: Kropotov
authors.forename: N V
authors.initials: NV
authors.lastname: Plaksen
authors.forename: N S
authors.initials: NS
authors.lastname: Khil'chenko
mesh_terms: D000818:Animals; D001769:Blood / Q000378:metabolism; D004305:Dose-Response Relationship, Drug; D045703:Emulsifying Agents / Q000633:toxicity*; D007928:Lethal Dose 50; D008297:Male; D051379:Mice; D010936:Plant Extracts / Q000633:toxicity*; D018517:Plant Roots / Q000737:chemistry; D051381:Rats; D017208:Rats, Wistar; D029750:Saponaria / Q000737:chemistry*; D018675:Toxicity Tests; D014675:Vegetables / Q000737:chemistry*
chemical_list: D045703:Emulsifying Agents; D010936:Plant Extracts