title: [Neurotoxicity related to lithium-risperidon combination treatment in a patient with schizoaffective disorder].
abstract: OBJECTIVE
  The case of a schizoaffective patient with a neurotoxic encephalopathy related to lithium-risperidon combination treatment is explored.
  
  
  METHODS
  A case report and the relevant theoretical and clinical deliberations are described.
  
  
  CONCLUSIONS
  Neurotoxicity related to lithium-risperidon combination treatment is the result of an interaction of different ethiopathogenetic mechanisms. The EEG is the most important diagnostic parameter.
authors.affiliation: Psychiatrische Universitätsklinik Zürich, Zürich, Switzerland. boeker@bli.unizh.ch
authors.forename: Heinz
authors.initials: H
authors.lastname: Böker
authors.forename: Mathias
authors.initials: M
authors.lastname: Brandenberger
authors.forename: Christian
authors.initials: C
authors.lastname: Schopper
mesh_terms: D018692:Antimanic Agents / Q000008:administration & dosage / Q000633:toxicity*; D014150:Antipsychotic Agents / Q000008:administration & dosage / Q000633:toxicity*; D003072:Cognition Disorders / Q000139:chemically induced / Q000175:diagnosis; D004347:Drug Interactions; D004359:Drug Therapy, Combination; D004409:Dyskinesia, Drug-Induced / Q000175:diagnosis*; D004569:Electroencephalography / Q000187:drug effects; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008875:Middle Aged; D009459:Neuroleptic Malignant Syndrome / Q000175:diagnosis*; D009460:Neurologic Examination / Q000187:drug effects; D020258:Neurotoxicity Syndromes / Q000175:diagnosis*; D011618:Psychotic Disorders / Q000188:drug therapy*; D018967:Risperidone / Q000008:administration & dosage / Q000633:toxicity*
chemical_list: D018692:Antimanic Agents; D014150:Antipsychotic Agents; D018967:Risperidone