title: Tuberculosis verrucosa cutis in a patient with long-standing generalized lichen planus: improvement of lichen after antitubercular polychemotherapy.
abstract: Tuberculosis verrucosa cutis (TBVC) is a rare form of skin tuberculosis in Western communities, and is generally seen in certain risk groups. A 52-year-old housewife with recalcitrant generalized cutaneous and mucosal lichen planus (LP) of more than a 20-year duration presented with an erythematous-edematous plaque with a warty surface containing deep hemorrhagic fissures and numerous orifices draining purulent material on the back of her left hand. On the basis of clinical, histological and bacteriological findings, TBVC was diagnosed. The patient was successfully treated with isoniazid, rifampicin, ethambutol and pyrazinamide. Interestingly, all lichen lesions improved completely with this therapy. To the best of our knowledge, this is the first documented case of TBVC associated with LP, which was cured by antitubercular polychemotherapy. The case is presented because it reflects a possible reciprocal causal relationship between two cutaneous conditions of different natures.
authors.affiliation: Departments of Dermatology, Gaziantep University Medical Faculty, Gaziantep, Turkey. zerbagci@yahoo.com
authors.forename: Zülal
authors.initials: Z
authors.lastname: Erbagci
authors.forename: Almla
authors.initials: A
authors.lastname: Tuncel
authors.forename: Nazan
authors.initials: N
authors.lastname: Bayram
authors.forename: Suna
authors.initials: S
authors.lastname: Erkilic
authors.forename: Aysen
authors.initials: A
authors.lastname: Bayram
mesh_terms: D000995:Antitubercular Agents / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008010:Lichen Planus / Q000150:complications* / Q000473:pathology*; D008875:Middle Aged; D014382:Tuberculosis, Cutaneous / Q000150:complications* / Q000188:drug therapy* / Q000473:pathology
chemical_list: D000995:Antitubercular Agents