Efficacy of duct tape vs placebo in the treatment of verruca vulgaris (warts) in primary school children.
OBJECTIVE
To determine the efficacy of duct tape compared with placebo in the treatment of verruca vulgaris.


METHODS
A randomized placebo-controlled trial in 3 primary schools in Maastricht, the Netherlands.


METHODS
One hundred three children aged 4 to 12 years with verruca vulgaris.


METHODS
Duct tape applied to the wart or placebo, a corn pad (protection ring for clavi), applied around the wart for 1 night a week. Both treatments were applied for a period of 6 weeks. Patients were blinded to the hypothesis of the study.


METHODS
Complete resolution of the treated wart.


RESULTS
After 6 weeks, the wart had disappeared in 16% of the children in the duct tape group compared with 6% in the placebo group (P = .12). The estimated effect of duct tape compared with placebo on diameter reduction of the treated wart was 1.0 mm (P = .02, 95% confidence interval, -1.7 to -0.1). After 6 weeks, in 7 children (21%) in the duct tape group, a surrounding wart had disappeared compared with 9 children (27%) in the placebo group (P = .79). Fifteen percent of the children in the duct tape group reported adverse effects such as erythema, eczema, and wounds compared with 0 in the placebo group (P = .14).


CONCLUSIONS
In a 6-week trial, duct tape had a modest but nonsignificant effect on wart resolution and diameter reduction when compared with placebo in a cohort of primary school children.
de Haen
Marloes
M
Departments of General Practice and Dermatology, Maastricht University, 6200 MD Maastricht, the Netherlands.
Spigt
Marcus G
MG
van Uden
Caro J T
CJ
van Neer
Pierre
P
Feron
Frans J M
FJ
Knottnerus
André
A
D000269:Adhesives; D001458:Bandages / Q000009:adverse effects; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008297:Male; D011446:Prospective Studies; D017211:Treatment Failure; D014860:Warts / Q000628:therapy*
D000269:Adhesives