Cutaneous manifestations of chronic graft-versus-host disease.
Cutaneous chronic graft versus host disease has traditionally been classified into lichenoid and scleroderma-like forms. However, the initial presentation is sometimes subtle and a variety of less common cutaneous manifestation may be prevalent. This clinical review focuses on the lesional morphology of chronic graft versus host disease, and presents a classification system that may prove useful in early diagnosis. In addition, this approach may help to facilitate the correlation of different morphologic entities with outcome and response to therapy.
Hymes
Sharon R
SR
Department of Dermatology, The MD Anderson Cancer Center, Houston, Texas 77030, USA. srhymes@mdanderson.org
Turner
Maria L
ML
Champlin
Richard E
RE
Couriel
Daniel R
DR
D006086:Graft vs Host Disease / Q000145:classification / Q000150:complications*; D018380:Hematopoietic Stem Cell Transplantation / Q000009:adverse effects*; D006801:Humans; D012871:Skin Diseases / Q000145:classification / Q000276:immunology*