title: Cross-species GacA-controlled induction of antibiosis in pseudomonads.
abstract: Signal extracts prepared from culture supernatants of Pseudomonas fluorescens CHA0 and Pseudomonas aeruginosa PAO stimulated GacA-dependent expression of small RNAs and hence of antibiotic compounds in both hosts. Pseudomonas corrugata LMG2172 and P. fluorescens SBW25 also produced signal molecules stimulating GacA-controlled antibiotic synthesis in strain CHA0, illustrating a novel, N-acyl-homoserine lactone-independent type of interspecies communication.
authors.affiliation: Département de Microbiologie Fondamentale, Université de Lausanne, CH-1015 Lausanne, Switzerland.
authors.forename: Christophe
authors.initials: C
authors.lastname: Dubuis
authors.forename: Dieter
authors.initials: D
authors.lastname: Haas
mesh_terms: D000900:Anti-Bacterial Agents / Q000378:metabolism*; D000898:Antibiosis; D001426:Bacterial Proteins / Q000378:metabolism*; D003470:Culture Media; D015964:Gene Expression Regulation, Bacterial; D011549:Pseudomonas / Q000145:classification / Q000378:metabolism / Q000502:physiology*; D011550:Pseudomonas aeruginosa / Q000378:metabolism / Q000502:physiology; D011551:Pseudomonas fluorescens / Q000378:metabolism / Q000502:physiology; D012329:RNA, Bacterial / Q000378:metabolism; D015398:Signal Transduction; D013045:Species Specificity
chemical_list: D000900:Anti-Bacterial Agents; D001426:Bacterial Proteins; D003470:Culture Media; C091100:GacA protein, Bacteria; D012329:RNA, Bacterial