title: Internal anterior chamber diameter using optical coherence tomography compared with white-to-white distances using automated measurements.
abstract: OBJECTIVE
  To compare internal horizontal anterior chamber (AC) diameter determined by optical coherence tomography (OCT) and horizontal corneal diameter (white-to-white [WTW]) using automated measurements.
  
  
  METHODS
  Department of Ophthalmology, Johann Wolfgang Goethe-University, Frankfurt am Main, Germany.
  
  
  METHODS
  Internal AC diameter and WTW distance was measured in 52 eyes of 26 patients using the Visante OCT (Carl Zeiss Meditec), IOLMaster (Carl Zeiss Meditec), and Orbscan IIz topography system (Bausch & Lomb). Statistical evaluation was performed using the Bland-Altman method and regression analysis for comparison of measurement techniques. The Kruskal-Wallis test was used to measure the repeatability of each device.
  
  
  RESULTS
  The mean internal AC diameter was 12.45 mm +/- 0.53 (SD) with OCT; the mean WTW distance was 12.17 +/- 0.45 mm with the IOLMaster and 11.84 +/- 0.41 mm with the Orbscan IIz. A positive regression was determined for AC diameter and both WTW measurements. Measurement values varied little between both WTW measurement systems (R(2) = 0.9384).
  
  
  CONCLUSIONS
  Anterior chamber measurement using optical coherence tomography (Visante OCT) was easy to handle and showed good repeatability. The internal horizontal diameter of the AC was larger than the horizontal corneal diameter determined by automated WTW measurements (IOLMaster, Orbscan IIz). Optical coherence tomography with the Visante OCT allows direct measurement of the AC width.
authors.affiliation: Department of Ophthalmology, Johann Wolfgang Goethe-University, Frankfurt am Main, Germany. kohnen@em.uni-frankfurt.de
authors.forename: Thomas
authors.initials: T
authors.lastname: Kohnen
authors.forename: Martin Christian
authors.initials: MC
authors.lastname: Thomala
authors.forename: Magdalena
authors.initials: M
authors.lastname: Cichocki
authors.forename: Anja
authors.initials: A
authors.lastname: Strenger
mesh_terms: D000328:Adult; D000867:Anterior Chamber / Q000033:anatomy & histology*; D001837:Body Weights and Measures; D019781:Corneal Topography / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015203:Reproducibility of Results; D041623:Tomography, Optical Coherence / Q000379:methods*