Molecular and clinical conditions associated with venous thromboembolism in oncological patients.
The association between cancer and thrombophilia has been known since 1865 since Trousseau described it. However in the last three decades an increased interest has been raised on this issue related to several molecular and condition that are involved in the daily management of oncological patients. This brief review has been focused on molecular conditions underlying cancer acquired thrombophilia then to further clinical aspects inducing thrombophilia in oncological patients such as surgery, chemotherapy, concomitant medical illness and inherited thrombophilia.
Di Micco
P
P
Division of Internal Medicine, Buonconsiglio Fatebenefratelli Hospital of Naples, Naples, Italy. pdimicco@libero.it
Amitrano
M
M
Niglio
A
A
Fontanella
A
A
D001780:Blood Coagulation Tests; D006801:Humans; D009369:Neoplasms / Q000150:complications* / Q000235:genetics; D010361:Patients; D013923:Thromboembolism / Q000175:diagnosis* / Q000209:etiology / Q000601:surgery; D019851:Thrombophilia / Q000150:complications* / Q000235:genetics*; D020246:Venous Thrombosis / Q000175:diagnosis* / Q000209:etiology / Q000601:surgery