Polyunsaturated fatty acids and neurological diseases.
This review summarizes the knowledge of the role of dietary PUFAs, especially omega-3, on normal brain function. Furthermore, it reports the evidence pointing to potential mechanisms of omega-3 fatty acids in development of neurological disorders and efficacy of their supplementation in terms of symptom management.
Salvati
S
S
Department of Food, Nutrition and Health, Istituto Superiore di Sanità, Rome, Italy. salvatis@iss.it
Attorri
L
L
Di Benedetto
R
R
Di Biase
A
A
Leonardi
F
F
D000818:Animals; D001921:Brain / Q000187:drug effects / Q000378:metabolism; D018450:Disease Progression; D005231:Fatty Acids, Unsaturated / Q000737:chemistry / Q000172:deficiency* / Q000378:metabolism* / Q000494:pharmacology; D006801:Humans; D009103:Multiple Sclerosis / Q000378:metabolism / Q000473:pathology; D009422:Nervous System Diseases / Q000378:metabolism* / Q000473:pathology
D005231:Fatty Acids, Unsaturated