Three-dimensional reconstruction and quantitative study of a pyramidal cell of a Cajal histological preparation.
The year 2006 marks the centenary of the Nobel Prize for Physiology or Medicine awarded to Santiago Ramón y Cajal and Camilo Golgi. We commemorate this centenary with a three-dimensional reconstruction and a quantitative study of a pyramidal cell of a Cajal's histological preparation. This preparation is one of the 4529 histological preparations personally made by Ramón y Cajal and preserved in the Museum Cajal. The three-dimensional reconstruction of the neuron allows visualizing one important discovery of Ramón y Cajal that constitutes an active field of research in present-day neuroscience: dendritic spines.
García-López
Pablo
P
Museo Cajal, Instituto Cajal, Consejo Superior de Investigaciones Cientificas, 28002 Madrid, Spain.
García-Marín
Virginia
V
Freire
Miguel
M
D000818:Animals; D002452:Cell Count / Q000379:methods; D002540:Cerebral Cortex / Q000166:cytology; D016591:Histocytological Preparation Techniques / Q000379:methods*; D021621:Imaging, Three-Dimensional / Q000379:methods*; D051379:Mice; D017966:Pyramidal Cells / Q000166:cytology*