title: Polypharmacy in oligopopulations: what psychiatric genetics can teach biological psychiatry.
abstract: Psychiatric genetics and genomics have made major strides in recent years. Some of that knowledge has yet to permeate in the clinical practice of biological psychiatry. The example of cancer-genetics, biology and clinical treatments may be profitable in terms of accelerating translational integration in psychiatry. We propose that current developments in genetics and genomics point to an Early Low-Dose Rational Polypharmacy in Oligopopulations model for psychiatric pharmacotherapy.
authors.affiliation: Laboratory of Neurophenomics, Institute of Psychiatric Research, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA. anicules@iupui.edu
authors.forename: Alexander B
authors.initials: AB
authors.lastname: Niculescu
mesh_terms: D004347:Drug Interactions; D005824:Genetics, Behavioral; D006801:Humans; D019338:Polypharmacy