Multiple intestinal lymphomatous polyposis in a Jindo dog.
A male, 5-year-old Jindo dog underwent enterectomy and enteroanastomosis due to ileus of the intestine at a local veterinary hospital. Grossly, the excised intestine showed markedly thickened multinodular masses in the serosal layer of the upper part, and soft-to-firm, cream-colored neoplastic masses that displayed extensive nodular mucosal protuberances into the lumen. The neoplastic masses were filled with large round cells that were ovoid in shape and they had pale and/or hyperchromatic nuclei. The neoplastic cells had mainly infiltrated into the mucosal and submucosal layers, and they had diffusely invaded the muscular and serosal layers. Therefore, the diagnosis of canine multiple intestinal malignant lymphomatous polyposis was made based on the gross and histopathological findings. The origin of these tumor cells was determined to be B-cells since they were positive for anti-CD20.
Jeong
Da-Hee
DH
Department of Pathology, College of Veterinary Medicine, Kyungpook National University, Daegu 702-701, Korea.
Do
Sun-Hee
SH
Hong
Il-Hwa
IH
Yang
Hai-Jie
HJ
Yuan
Dong-Wei
DW
Choi
Dong-Hag
DH
Jeong
Kyu-Shik
KS
D000818:Animals; D018951:Antigens, CD20 / Q000378:metabolism; D004283:Dog Diseases / Q000473:pathology* / Q000601:surgery; D004285:Dogs; D007150:Immunohistochemistry / Q000662:veterinary; D007414:Intestinal Neoplasms / Q000473:pathology / Q000601:surgery / Q000662:veterinary*; D007417:Intestinal Polyps / Q000473:pathology* / Q000601:surgery; D020522:Lymphoma, Mantle-Cell / Q000473:pathology / Q000601:surgery / Q000662:veterinary*; D008297:Male
D018951:Antigens, CD20