title: [Mechanism of wenpi decoction delaying progression of chronic renal failure].
abstract: Wenpi decoction ameliorates the harmful factors of chronic renal failure, such as mesangial matrix and its cytokines, nuclear factor, endothelium-dependent relaxing factor, oxidative free raidical, apoptosis, lipide, protein, and blood rheology. Wenpi decoction is an effective agent for delaying the progression of chronic renal failure.
authors.affiliation: Department of Traditional Chinese Medicine, Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing 210008, China.
authors.forename: Jie
authors.initials: J
authors.lastname: Zhang
authors.forename: Yi-Gang
authors.initials: YG
authors.lastname: Wan
mesh_terms: D000818:Animals; D017209:Apoptosis / Q000187:drug effects; D049109:Cell Proliferation / Q000187:drug effects; D018450:Disease Progression; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification / Q000494:pharmacology*; D045462:Endothelium-Dependent Relaxing Factors / Q000378:metabolism; D007676:Kidney Failure, Chronic / Q000378:metabolism / Q000473:pathology; D050527:Mesangial Cells / Q000166:cytology; D016328:NF-kappa B / Q000378:metabolism; D010946:Plants, Medicinal / Q000737:chemistry; D013482:Superoxide Dismutase / Q000378:metabolism
chemical_list: D004338:Drug Combinations; D004365:Drugs, Chinese Herbal; D045462:Endothelium-Dependent Relaxing Factors; D016328:NF-kappa B; C523153:wenpi decoction; D013482:Superoxide Dismutase