title: Bone mineral density in hip-fracture patients with Parkinson's disease: a case-control study.
abstract: OBJECTIVE
  To investigate bone mineral density (BMD) levels in patients with Parkinson's disease (PD) who sustained a hip fracture.
  
  
  METHODS
  Case-control study.
  
  
  METHODS
  Rehabilitation hospital in Italy.
  
  
  METHODS
  We investigated 831 out of 887 white patients consecutively admitted to a rehabilitation hospital because of an original hip fracture resulting from a fall. Twenty-eight (3.37%) of the 831 patients were affected by PD. Twenty-eight controls matched for sex, age, and hip-fracture type (cervical or trochanteric) were found among the 803 non-PD patients.
  
  
  METHODS
  Not applicable.
  
  
  METHODS
  BMD was assessed by dual-energy x-ray absorptiometry (DXA) at the unfractured femur. Five sites were investigated in each subject: total proximal femur, femoral neck, trochanter, intertrochanteric area, and Ward's triangle. DXA scan was performed a mean +/- standard deviation of 22.2 +/- 7.8 days after fracture occurrence in the 28 patients and 22.0 +/- 5.3 days after fracture occurrence in the 28 controls.
  
  
  RESULTS
  BMD expressed as a T score did not differ significantly between the 28 PD patients and the 28 controls, whereas z score in the PD patients was significantly lower than 0 +/- 1 in the age- and sex-matched general population at 4 of the 5 sites of BMD assessment.
  
  
  CONCLUSIONS
  A sample of PD fallers who sustained a hip fracture had femoral BMD levels similar to those found in matched hip-fracture fallers who did not suffer from PD and significantly lower than those found in the matched reference population.
authors.affiliation: Osteoporosis Research Center, Presidio Sanitario San Camillo, Torino, Italy. Merdici@h-sancamillo.to.it
authors.forename: Marco
authors.initials: M
authors.lastname: Di Monaco
authors.forename: Fulvia
authors.initials: F
authors.lastname: Vallero
authors.forename: Roberto
authors.initials: R
authors.lastname: Di Monaco
authors.forename: Rosa
authors.initials: R
authors.lastname: Tappero
authors.forename: Alberto
authors.initials: A
authors.lastname: Cavanna
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D015519:Bone Density; D016022:Case-Control Studies; D005260:Female; D006620:Hip Fractures / Q000145:classification / Q000150:complications / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010300:Parkinson Disease / Q000150:complications*