title: Management of coagulopathy in the setting of acute neurosurgical disease and injury.
abstract: Blood coagulation and hemostasis issues are important aspects of patient care in acute neurosurgical patients. Coagulopathy often complicates the already difficult management of cerebrovascular and intracranial hemorrhagic disease and injuries, adding to the already high associated morbidity and mortality. Common causes of coagulopathy, as well as its management in acute neurosurgical settings, are outlined in this review. Awareness of how to promptly evaluate and effectively treat coagulopathic processes is instrumental to the success of the neurosurgeon in managing acute intracranial pathologies.
authors.affiliation: Department of Neurosurgery, University of California, Irvine, CA 92868, USA.
authors.forename: Marlon
authors.initials: M
authors.lastname: Mathews
authors.forename: Richard
authors.initials: R
authors.lastname: Newman
authors.forename: E Thomas
authors.initials: ET
authors.lastname: Chappell
mesh_terms: D000208:Acute Disease; D001777:Blood Coagulation / Q000502:physiology*; D001778:Blood Coagulation Disorders / Q000503:physiopathology / Q000628:therapy; D004912:Erythrocytes / Q000378:metabolism; D006487:Hemostasis / Q000502:physiology; D006801:Humans; D009422:Nervous System Diseases / Q000473:pathology / Q000503:physiopathology / Q000601:surgery; D009493:Neurosurgery; D012307:Risk Factors