title: [Acute hemorrhagic colitis induced by the neuraminidase inhibitor oseltamivir].
abstract: A 23-year-old woman had lower abdominal pain, diarrhea and bloody stool was admitted and given a diagnosis of influenza B. Her home doctor had started treatment by neuraminidase inhibitor (oseltamivir) the previous day. Colonoscopic examination revealed an area of hemorrhage and erosion in the left transverse colon. After halting oseltamivir treatment these symptoms disappeared and her colonoscopic findings improved. A drug-induced lymphocyte stimulation test was positive for oseltamivir. This case is the first reported case of acute hemorrhagic colitis induced by oseltamivir.
authors.affiliation: Department of Internal Medicine, Takanohara General Hospital.
authors.forename: Satoshi
authors.initials: S
authors.lastname: Yoneda
authors.forename: Yozo
authors.initials: Y
authors.lastname: Kobayashi
authors.forename: Takehiro
authors.initials: T
authors.lastname: Nunoi
authors.forename: Kosuke
authors.initials: K
authors.lastname: Takeda
authors.forename: Atsushi
authors.initials: A
authors.lastname: Matsumori
authors.forename: Minoru
authors.initials: M
authors.lastname: Andoh
authors.forename: Hirohisa
authors.initials: H
authors.lastname: Tsujinoue
authors.forename: Kimio
authors.initials: K
authors.lastname: Nishimura
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Fukui
mesh_terms: D000328:Adult; D000998:Antiviral Agents / Q000009:adverse effects*; D003092:Colitis / Q000139:chemically induced*; D005260:Female; D006471:Gastrointestinal Hemorrhage / Q000139:chemically induced*; D006801:Humans; D009981:Influenza B virus; D007251:Influenza, Human / Q000188:drug therapy; D009439:Neuraminidase / Q000037:antagonists & inhibitors*; D053139:Oseltamivir / Q000009:adverse effects*
chemical_list: D000998:Antiviral Agents; D053139:Oseltamivir; D009439:Neuraminidase