Control of pyramidal inversion rates by redox switching.
The dynamics of pyramidal nitrogen inversion can be controlled by reversible redox switching in trans-2,3-diphenylaziridines bearing a suitable 1,4-naphthaquinone substituent. In the reduced form, an intramolecular H-bond significantly raises the inversion barrier slowing this molecular motion by >50-fold. The experimental findings are further supported by DFT calculations.
Davies
Mark W
MW
Department of Chemistry, University of Warwick, Coventry, UK.
Shipman
Michael
M
Tucker
James H R
JH
Walsh
Tiffany R
TR