title: Diuretic and analgesic effects of the methanol extract of Phoenix sylvestris root.
abstract: The analgesic and diuretic activities of the methanol extract of Phoenix sylvestris root on Swiss albino mice were observed. The extract showed significant (p<0.001) analgesic activity by reduction of percent inhibition of writhing induced by acetic acid (0.5% v/v) in 20.07% and 32.57% at a dose level of 150 mg/kg and 300-mg/kg body weights respectively. The methanol extract also showed diuretic effect at 1st hour of the study at 300-mg/kg and 2nd and 4th hour of the study at 150-mg/kg-body weight on swiss albino mice. The onset of diuretic effect was faster at a dose of 300-mg/kg body weights than 150 mg/kg body weight. The obtained results may give a clue for extensive phytochemical investigation of the plant for the development of herbal medicine.
authors.affiliation: Department of Pharmacology & Clinical Pharmacy, University of Dhaka, Dhaka 1000, Bangladesh.
authors.forename: M A B
authors.initials: MA
authors.lastname: Howlader
authors.forename: S C
authors.initials: SC
authors.lastname: Bachar
authors.forename: F
authors.initials: F
authors.lastname: Begum
authors.forename: A S S
authors.initials: AS
authors.lastname: Rouf
mesh_terms: D000700:Analgesics / Q000494:pharmacology*; D000818:Animals; D004232:Diuretics / Q000494:pharmacology*; D005260:Female; D008297:Male; D051379:Mice; D010936:Plant Extracts / Q000494:pharmacology*; D018517:Plant Roots; D014197:Trees
chemical_list: D000700:Analgesics; D004232:Diuretics; D010936:Plant Extracts