Adenosine-to-inosine RNA editing: perspectives and predictions.
Adenosine-to-Inosine RNA editing introduces changes in RNA transcripts via a post-transcriptional mechanism, the hydrolytic deamination of adenosine (A) to inosine (I) which is interpreted as guanosine by cellular machineries. Adenosine deaminases that act on RNA (ADAR) enzymes catalyze editing in double-stranded (ds) RNA substrates.
Hoopengardner
Barry
B
Central Connecticut State University, Department of Biomolecular Sciences, 1615 Stanley Street, New Britain, Connecticut 06050, USA. hoopengardnbam@ccsu.edu.
D000241:Adenosine / Q000737:chemistry / Q000235:genetics*; D000818:Animals; D014644:Genetic Variation / Q000235:genetics; D016678:Genome / Q000235:genetics; D006801:Humans; D007288:Inosine / Q000737:chemistry / Q000235:genetics*; D017393:RNA Editing / Q000235:genetics*
D007288:Inosine; D000241:Adenosine