Acute toxicity, behavioral changes, and histopathological effects of deltamethrin on tissues (gills, liver, brain, spleen, kidney, muscle, skin) of Nile tilapia (Oreochromis niloticus L.) fingerlings.
Deltamethrin, a synthetic pyrethroid contaminating aquatic ecosystems as a potential toxic pollutant, was investigated in the present study for acute toxicity. The purpose of this study was to evaluate LC(50) values of deltamethrin on Nile tilapia (Oreochromis niloticus L.) fingerlings and investigate histopathological responses of fish exposed to deltamethrin. The 48 h LC(50) value for Nile tilapia fingerlings was estimated as 4.85 microg/L using static test system. In addition, behavioral changes at each deltamethrin concentration were observed closely. All fish, exposed to 5 microg/L deltamethrin revealed severe morphological alterations in the gills and liver. In the gills hyperemia, fusion of secondary lamellae and telangiectasis were observed; whereas hydropic degenerations in liver were observed in all examined fish. The results are significant for reporting acute deltamethrin toxicity in terms of behavioral and histopathological changes: Deltamethrin is highly toxic to fingerlings.
Yildirim
M Ziynet
MZ
Department of Pathology, Faculty of Veterinary Medicine, Ankara University, Dişkapi, Ankara 06110, Turkey.
Benli
A Cağlan Karasu
AC
Selvi
Mahmut
M
Ozkul
Ayhan
A
Erkoç
Figen
F
Koçak
Oner
O
D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects*; D023681:Cichlids / Q000033:anatomy & histology / Q000254:growth & development / Q000378:metabolism*; D004784:Environmental Monitoring / Q000379:methods; D005880:Gills / Q000187:drug effects / Q000473:pathology; D007306:Insecticides / Q000633:toxicity*; D007668:Kidney / Q000187:drug effects / Q000473:pathology; D008099:Liver / Q000187:drug effects / Q000473:pathology; D009132:Muscles / Q000187:drug effects / Q000473:pathology; D009570:Nitriles / Q000633:toxicity*; D011722:Pyrethrins / Q000633:toxicity*; D012867:Skin / Q000187:drug effects / Q000473:pathology; D013154:Spleen / Q000187:drug effects / Q000473:pathology; D023382:Toxicity Tests, Acute
D007306:Insecticides; D009570:Nitriles; D011722:Pyrethrins; C017180:decamethrin