title: The histone to protamine ratio in human spermatozoa: comparative study of whole and processed semen.
abstract: Sperm protamine deficiency has been demonstrated in some infertile men and may be an important determinant of sperm DNA integrity. We sought to examine and compare the sperm nuclear histone to protamine ratio in whole and processed semen samples from fertile and infertile men.
authors.affiliation: Division of Urology, Department of Surgery, Royal Victoria Hospital, McGill University, Montreal, Quebec, Canada. armand.zini@ssss.gouv.qc.ca <armand.zini@ssss.gouv.qc.ca>
authors.forename: Armand
authors.initials: A
authors.lastname: Zini
authors.forename: Maria San
authors.initials: MS
authors.lastname: Gabriel
authors.forename: Xiaoyang
authors.initials: X
authors.lastname: Zhang
mesh_terms: D006657:Histones / Q000032:analysis*; D006801:Humans; D007248:Infertility, Male / Q000378:metabolism*; D008297:Male; D011479:Protamines / Q000032:analysis*; D012661:Semen / Q000378:metabolism*; D013094:Spermatozoa / Q000378:metabolism*
chemical_list: D006657:Histones; C082073:PRM1 protein, human; D011479:Protamines; C068621:protamine 2