title: Vaginal discharge and bleeding in girls younger than 6 years.
abstract: OBJECTIVE
  Persistent unexplained vaginal discharge or bleeding in the pediatric population may be the only manifestation of a serious underlying medical or social problem. Therefore, these symptoms require careful and complete evaluation to identify the primary pathology accurately. We retrospectively reviewed charts of patients who presented for evaluation of persistent vaginal discharge or bleeding to determine if noninvasive imaging was a sensitive means of screening for gynecological pathology.
  
  
  METHODS
  The records of 24 girls younger than 6 years who presented with vaginal discharge or bleeding were reviewed retrospectively. All patients were evaluated with noninvasive imaging, a pelvic examination while under anesthesia, vaginoscopy and cystoscopy.
  
  
  RESULTS
  Noninvasive imaging was useful in identifying 5 of 7 vaginal foreign bodies. However, noninvasive imaging identified only 2 of 6 malignancies. These malignancies consisted of rhabdomyosarcoma (3 patients) and endodermal sinus tumor (3). Two girls also had benign vaginal mullerian papillomas that were not identified by noninvasive imaging. Noninvasive imaging did not aid in the diagnosis of sexual abuse.
  
  
  CONCLUSIONS
  Based on these data, we recommend that all girls younger than 6 years who present with persistent vaginal discharge or bleeding be evaluated with pelvic examination while under anesthesia, to be followed by vaginoscopy and cystoscopy if no readily identifiable pathology is found by simple genital examination alone, regardless of the results of noninvasive imaging studies.
authors.affiliation: Department of Urology, Children's Hospital, Denver, Colorado, USA.
authors.forename: A M
authors.initials: AM
authors.lastname: Striegel
authors.forename: J B
authors.initials: JB
authors.lastname: Myers
authors.forename: M D
authors.initials: MD
authors.lastname: Sorensen
authors.forename: P D
authors.initials: PD
authors.lastname: Furness
authors.forename: M A
authors.initials: MA
authors.lastname: Koyle
mesh_terms: D002675:Child, Preschool; D005260:Female; D005547:Foreign Bodies / Q000150:complications / Q000175:diagnosis*; D006801:Humans; D007223:Infant; D012208:Rhabdomyosarcoma / Q000150:complications / Q000175:diagnosis; D019522:Vaginal Discharge / Q000175:diagnosis* / Q000209:etiology; D014623:Vaginal Diseases / Q000175:diagnosis* / Q000209:etiology; D014625:Vaginal Neoplasms / Q000150:complications / Q000175:diagnosis