title: Involvement of the bed nucleus of the stria terminalis in the negative affective component of visceral and somatic pain in rats.
abstract: Using a conditioned place paradigm, we examined the involvement of the bed nucleus of the stria terminalis (BST) in the negative affective component of visceral and somatic pain induced by intraperitoneal acetic acid and intraplantar formalin injections, respectively, in rats. Bilateral BST lesions suppressed both the acetic acid- and formalin-induced conditioned place aversion, suggesting the crucial role of the BST in the negative affective component of visceral and somatic pain.
authors.affiliation: Department of Pharmacology, Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo 060-0812, Japan.
authors.forename: Satoshi
authors.initials: S
authors.lastname: Deyama
authors.forename: Takayuki
authors.initials: T
authors.lastname: Nakagawa
authors.forename: Shuji
authors.initials: S
authors.lastname: Kaneko
authors.forename: Takashi
authors.initials: T
authors.lastname: Uehara
authors.forename: Masabumi
authors.initials: M
authors.lastname: Minami
mesh_terms: D019342:Acetic Acid; D000704:Analysis of Variance; D000818:Animals; D001362:Avoidance Learning / Q000502:physiology; D001522:Behavior, Animal; D003213:Conditioning, Psychological; D005557:Formaldehyde; D008297:Male; D009434:Neural Pathways / Q000503:physiopathology*; D010146:Pain / Q000139:chemically induced / Q000503:physiopathology*; D010147:Pain Measurement / Q000379:methods; D051381:Rats; D017207:Rats, Sprague-Dawley; D011930:Reaction Time / Q000502:physiology; D012686:Septal Nuclei / Q000293:injuries / Q000503:physiopathology*; D013997:Time Factors
chemical_list: D005557:Formaldehyde; D019342:Acetic Acid