[Characterization of platelets aggregation inhibitor from Agkistrodon blomhoffii ussuriensis snake venom].
Platelet aggregation inhibitor--"Blomus-B" from Agkistrodon blomhoffii ussuriensis venom has been isolated by affinity and ion-exchange chromatography. The purified inhibitor is a novel non-enzymatic single-chain protein with molecular weigth of 13 kDa. "Blomus-B" causes a change of platelets shape and takes effect on ADP- and adrenalin-induced platelet aggregation.
Karbovs'kyĭ
V L
VL
Savchuk
O M
OM
Volkov
H L
HL
Zaichko
N V
NV
Bykhan
Ts
Ts
D017836:Agkistrodon; D000818:Animals; D002850:Chromatography, Gel; D003435:Crotalid Venoms / Q000737:chemistry*; D066298:In Vitro Techniques; D008970:Molecular Weight; D010974:Platelet Aggregation / Q000187:drug effects*; D010975:Platelet Aggregation Inhibitors / Q000302:isolation & purification / Q000494:pharmacology; D011817:Rabbits; D013997:Time Factors
C031442:Agkistrodon venoms; D003435:Crotalid Venoms; D010975:Platelet Aggregation Inhibitors