title: Clinical and radiographic features of peritumoral infarction following resection of glioblastoma.
abstract: Focal areas of restricted diffusion adjacent to high-grade glioma resection cavities were detected in 70% of patients on immediate postoperative MRI studies. Follow-up studies demonstrated cystic encephalomalacia in 91% of these foci, suggesting the presence of infarction, and the infarcted tissue demonstrated enhancement in 43% of cases. New postoperative deficits correlated well with the anatomic region of infarction in six patients. Enhancement in perioperative infarcts can mimic tumor progression on follow-up imaging studies.
authors.affiliation: Stephen E. Catherine Pappas Center for Neuro-oncology and Division of Neuroradiology, Massachusetts General Hospital, Boston, MA 02114, USA.
authors.forename: S
authors.initials: S
authors.lastname: Ulmer
authors.forename: T A
authors.initials: TA
authors.lastname: Braga
authors.forename: F G
authors.initials: FG
authors.lastname: Barker
authors.forename: M H
authors.initials: MH
authors.lastname: Lev
authors.forename: R G
authors.initials: RG
authors.lastname: Gonzalez
authors.forename: J W
authors.initials: JW
authors.lastname: Henson
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001921:Brain / Q000098:blood supply / Q000473:pathology / Q000503:physiopathology; D020520:Brain Infarction / Q000209:etiology* / Q000473:pathology* / Q000503:physiopathology; D001932:Brain Neoplasms / Q000098:blood supply / Q000503:physiopathology / Q000601:surgery*; D002536:Cerebral Arteries / Q000293:injuries / Q000473:pathology / Q000503:physiopathology; D002560:Cerebrovascular Circulation / Q000502:physiology; D003221:Confusion / Q000209:etiology / Q000473:pathology / Q000503:physiopathology; D038524:Diffusion Magnetic Resonance Imaging / Q000592:standards; D005260:Female; D005909:Glioblastoma / Q000098:blood supply / Q000503:physiopathology / Q000601:surgery*; D006801:Humans; D008297:Male; D008833:Microcirculation / Q000293:injuries / Q000473:pathology / Q000503:physiopathology; D008875:Middle Aged; D019635:Neurosurgical Procedures / Q000009:adverse effects*; D010291:Paresis / Q000209:etiology / Q000473:pathology / Q000503:physiopathology; D011183:Postoperative Complications / Q000209:etiology* / Q000473:pathology* / Q000503:physiopathology; D011237:Predictive Value of Tests