title: [The practice guideline 'Diabetes mellitus type 2' (second revision) from the Dutch College of General Practitioners; a response from the perspective of internal medicine].
abstract: The revised guideline 'Diabetes mellitus type 2' contains several improvements. The HbA1C target level has been lowered to 7% or less. The universal first step in oral therapy has become metformin. The target level for the treatment of hypertension is now a systolic pressure below 140 mmHg. Statins should be prescribed to almost every patient. Finally, ACE-inhibitors are now suggested for all patients with microalbuminuria and hypertension. Some choices made in the present guideline are not evidence-based, e.g. the advice to prescribe pioglitazone to patients with both a body mass index above 27 kg/m2 and cardiovascular disease, but without heart failure. Still, in general, the updated guideline is an important document which has been greatly improved in comparison to the former one.
authors.affiliation: Academisch Medisch Centrum/Universiteit van Amsterdam, Afd. Inwendige Geneeskunde, Meibergdreef 9, 1105, AZ Amsterdam.
authors.forename: F
authors.initials: F
authors.lastname: Holleman
authors.forename: J H
authors.initials: JH
authors.lastname: de Vries
authors.forename: J B L
authors.initials: JB
authors.lastname: Hoekstra
mesh_terms: D003924:Diabetes Mellitus, Type 2 / Q000175:diagnosis* / Q000188:drug therapy*; D006442:Glycated Hemoglobin / Q000032:analysis; D006801:Humans; D007004:Hypoglycemic Agents / Q000627:therapeutic use; D007388:Internal Medicine / Q000592:standards*; D009426:Netherlands; D017410:Practice Guidelines as Topic; D010818:Practice Patterns, Physicians'; D012955:Societies, Medical
chemical_list: D006442:Glycated Hemoglobin; D007004:Hypoglycemic Agents