Sudden cardiac death in young children with neurofibromatosis type 1.
Patients with neurofibromatosis type 1 (NF1) can manifest a characteristic vasculopathy that in adults is rarely associated with fatal coronary artery occlusion. We describe the clinical and pathological findings from 2 unrelated young children with NF1, a similar vasculopathy affecting their coronary arteries, and sudden cardiac death.
Kanter
Ronald J
RJ
Division of Pediatric Cardiology, Department of Pediatrics, Duke University School of Medicine, Durham, NC 27710, USA.
Graham
Matthew
M
Fairbrother
David
D
Smith
S Victor
SV
D002648:Child; D023921:Coronary Stenosis / Q000150:complications / Q000473:pathology; D003330:Coronary Vessel Anomalies / Q000150:complications / Q000473:pathology; D016757:Death, Sudden, Cardiac / Q000209:etiology* / Q000473:pathology; D017809:Fatal Outcome; D006338:Heart Neoplasms / Q000150:complications* / Q000473:pathology; D006801:Humans; D007223:Infant; D008297:Male; D009203:Myocardial Infarction / Q000209:etiology; D009456:Neurofibromatosis 1 / Q000150:complications* / Q000473:pathology