[Early metabolic abnormalities--insulin resistance, hyperinsulinemia, impaired glucose tolerance and diabetes, in adolescent girls with polycystic ovarian syndrome].
Polycystic ovary syndrome (PCOS), the main androgen disorder in women. Recently, it has been suggested that the condition is hereditary and that women with PCOS have disturbances, such as hyperandrogenism and additional metabolic abnormalities as hyperinsulinaemia, increased insulin resistance, dyslipidemia. Polycystic ovary syndrome (PCOS) usually arises during puberty and is marked by hyperinsulinemia and hyperandrogenism. Adolescents with PCOS are at an increased risk of developing health problems later on in life such as type 2 diabetes, cardiovascular disease, and infertility. Furthermore, the physical signs of PCOS can be detrimental to a teenage girl's self-image. Early diagnosis and treatment of PCOS in adolescents are essential in ensuring adulthood health and restoring self-esteem. Treatment for an adolescent with PCOS includes diet and exercise, metformin, and oral contraceptive pills. Still, surgery is not indicated in teenagers. Furthermore, psychological factors must be taken into consideration as well.
Otto-Buczkowska
Ewa
E
Górnoślaskie Centrum Zdrowia Dziecka i Matki w Katowicach. em.buczkowski@pro.onet.pl
Jarosz-Chobot
Przemysława
P
Deja
Grazyna
G
D000293:Adolescent; D000328:Adult; D003920:Diabetes Mellitus / Q000188:drug therapy / Q000209:etiology; D004700:Endocrine System Diseases / Q000209:etiology; D005260:Female; D018149:Glucose Intolerance / Q000209:etiology; D006801:Humans; D017588:Hyperandrogenism / Q000188:drug therapy / Q000209:etiology / Q000378:metabolism; D006946:Hyperinsulinism / Q000209:etiology; D007004:Hypoglycemic Agents / Q000008:administration & dosage; D007333:Insulin Resistance; D009765:Obesity / Q000209:etiology / Q000378:metabolism; D011085:Polycystic Ovary Syndrome / Q000150:complications* / Q000175:diagnosis* / Q000628:therapy; D011627:Puberty
D007004:Hypoglycemic Agents