title: Colorectal cancer screening.
abstract: Colorectal cancer is a major public health burden worldwide. There is clear-cut evidence that screening will reduce colorectal cancer mortality and the only contentious issue is which screening tool to use. Most evidence points towards screening with fecal occult blood testing. The immunochemical fecal occult blood tests have a higher sensitivity than the guaiac-based tests. In addition, their automation and haemoglobin quantification allows a threshold for colonoscopy to be selected that can be accommodated within individual health care systems.
authors.forename: Ramona-M
authors.initials: RM
authors.lastname: McLoughlin
authors.forename: Colm-A
authors.initials: CA
authors.lastname: O'Morain
mesh_terms: D000368:Aged; D003113:Colonoscopy; D015179:Colorectal Neoplasms / Q000175:diagnosis* / Q000517:prevention & control*; D004733:Enema; D006138:Guaiac; D006801:Humans; D008403:Mass Screening / Q000379:methods*; D008875:Middle Aged; D009780:Occult Blood; D012680:Sensitivity and Specificity; D012812:Sigmoidoscopy
chemical_list: D006138:Guaiac