Multiple verrucous carcinomas treated with acitretin.
Cutaneous verrucous carcinoma is a rare variant of low-grade squamous cell carcinoma. It usually involves distal extremities and is often misdiagnosed as giant warts. Multiple cutaneous verrucous carcinomas are rare in the English-language literature. We describe a 41-year-old man with multiple verrucous plaques on both feet and ankles, as well as the left thigh. Immunohistochemical study with proliferating cell nuclear antigen revealed positive staining of the basal and suprabasal layers. The patient's condition was successfully treated with systemic acitretin.
Kuan
Yue-Zon
YZ
Department of Dermatology, Chang Gung Memorial Hospital, Taipei 105, Taiwan.
Hsu
Hsiu-cheng
HC
Kuo
Tseng-tong
TT
Huang
Yu-Huei
YH
Ho
Hsin-Chun
HC
D017255:Acitretin / Q000627:therapeutic use*; D000328:Adult; D018289:Carcinoma, Verrucous / Q000188:drug therapy* / Q000378:metabolism / Q000473:pathology; D006801:Humans; D007150:Immunohistochemistry / Q000379:methods; D007641:Keratolytic Agents / Q000627:therapeutic use*; D007866:Leg; D008297:Male; D018809:Proliferating Cell Nuclear Antigen / Q000378:metabolism; D012878:Skin Neoplasms / Q000188:drug therapy* / Q000378:metabolism / Q000473:pathology; D013194:Staining and Labeling
D007641:Keratolytic Agents; D018809:Proliferating Cell Nuclear Antigen; D017255:Acitretin