[Air pollution and cardiovascular and cerebrovascular disease. Pathophysiologic basis and groups at risk].
The pathophysiologic basis of the harmful action of air pollutants rests principally on their proinflammatory and prothrombotic effects. The principal pollutants currently identified as responsible for these effects are fine suspended particles (PM2.5) and ozone. Inflammatory effects, initially localized in the lungs, then become systemic. Analysis of groups at the highest risk of atherothrombotic events suggests the elderly may be most sensitive to the effects of air pollution.
Zeller
Marianne
M
Observatoire des infarctus de Côte-d'Or (RICO). Electronic address: marianne.zeller@u-bourgogne.fr.
Giroud
Maurice
M
Registre dijonnais des accidents vasculaires cérébraux.
Royer
Clotilde
C
Observatoire des infarctus de Côte-d'Or (RICO).
Benatru
Isabelle
I
Registre dijonnais des accidents vasculaires cérébraux.
Besancenot
Jean-Pierre
JP
Climat et santé, Faculté de médecine, Dijon (21).
Rochette
Luc
L
Observatoire des infarctus de Côte-d'Or (RICO).
Cottin
Yves
Y
Observatoire des infarctus de Côte-d'Or (RICO).
D000367:Age Factors; D000368:Aged; D000393:Air Pollutants / Q000009:adverse effects*; D000397:Air Pollution / Q000009:adverse effects* / Q000517:prevention & control; D050197:Atherosclerosis / Q000453:epidemiology / Q000209:etiology; D002318:Cardiovascular Diseases / Q000453:epidemiology* / Q000503:physiopathology; D002561:Cerebrovascular Disorders / Q000453:epidemiology* / Q000503:physiopathology; D003327:Coronary Disease / Q000150:complications; D048909:Diabetes Complications; D006801:Humans; D008168:Lung / Q000187:drug effects; D010083:Oxidants, Photochemical / Q000009:adverse effects; D010126:Ozone / Q000009:adverse effects; D052638:Particulate Matter / Q000009:adverse effects; D018570:Risk Assessment; D012307:Risk Factors; D012907:Smoking / Q000009:adverse effects; D013927:Thrombosis / Q000453:epidemiology / Q000209:etiology; D013997:Time Factors
D000393:Air Pollutants; D010083:Oxidants, Photochemical; D052638:Particulate Matter; D010126:Ozone