title: Approaches to document the efficacy and safety of microdermabrasion procedure.
abstract: BACKGROUND
  Microdermabrasion is a popular cosmetic procedure for skin rejuvenation, which is achieved by mechanical abrasion of the skin at a superficial level.
  
  
  OBJECTIVE
  The objective was to study the efficacy of microdermabrasion in photoaging and to investigate the compatibility of a cleanser and a lotion with microdermabrasion.
  
  
  METHODS
  Sixteen women underwent microdermabrasion to the face once a week for a total of six treatments. Subjects were also given a personal skin care regimen (cleanser and lotion). Colorimetry values as well as investigator and patients ratings for safety and efficacy were analyzed at various time points and compared to baseline.
  
  
  RESULTS
  There were no significant changes in safety and tolerance variables throughout the study. Clinical efficacy variables (fine wrinkles, dullness, pigmentation, and large pores) significantly improved by the third treatment, with further improvement by the end of the study (six treatments). Subjects perceived improvement in facial photoaging variables. Colorimetry showed increased brightness and decreased yellowness of target skin sites on the face throughout the study.
  
  
  CONCLUSIONS
  Multiple microdermabrasions were effective in significantly improving various facial photoaging variables. The personal skin care regimen used was well tolerated by the subjects.
authors.affiliation: Mount Sinai School of Medicine, New York, New York, USA.
authors.forename: James M
authors.initials: JM
authors.lastname: Spencer
authors.forename: Ellen S
authors.initials: ES
authors.lastname: Kurtz
mesh_terms: D000328:Adult; D003124:Colorimetry; D003869:Dermabrasion / Q000379:methods*; D005145:Face / Q000473:pathology / Q000601:surgery*; D005260:Female; D006801:Humans; D008548:Melanosis / Q000473:pathology / Q000601:surgery*; D008875:Middle Aged; D012720:Severity of Illness Index; D015595:Skin Aging / Q000473:pathology; D016896:Treatment Outcome