title: Subtle computed tomography abnormalities in cerebral deep sinus thrombosis.
abstract: A patient with cerebral deep sinus thrombosis, which was not diagnosed on the first examination, is reported. A 46-year-old woman presented with headache and vomiting. Neurological examination and a brain computed tomography (CT) scan showed no obvious abnormal findings. The patient suffered disturbed consciousness on the day after the examination, and was admitted to our emergency centre. A CT scan and magnetic resonance imaging revealed an ischaemic lesion in the left basal ganglia, suggesting deep sinus occlusion. Anticoagulant therapy was administered. One day after admission, a CT scan showed a haematoma and severe brain swelling in the same region. Cerebral angiography demonstrated a straight sinus occlusion. Intracranial pressure was not controlled with hypothermia, and the patient died 25 days after admission. Review of the initial CT scan revealed subtle, early findings of deep venous thrombosis that were missed on first examination.
authors.affiliation: Department of Emergency and Intensive Care Medicine, Shinshu University School of Medicine, Matsumoto, Japan.
authors.forename: Tomomi
authors.initials: T
authors.lastname: Iwashita
authors.forename: Kazuo
authors.initials: K
authors.lastname: Kitazawa
authors.forename: Jun-Ichi
authors.initials: J
authors.lastname: Koyama
authors.forename: Hisashi
authors.initials: H
authors.lastname: Nagashima
authors.forename: Toru
authors.initials: T
authors.lastname: Koyama
authors.forename: Yuichiro
authors.initials: Y
authors.lastname: Tanaka
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Hongo
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Okudera
authors.forename: Kazufumi
authors.initials: K
authors.lastname: Okamoto
mesh_terms: D000925:Anticoagulants / Q000627:therapeutic use; D001479:Basal Ganglia / Q000000981:diagnostic imaging / Q000473:pathology; D002533:Cerebral Angiography; D017809:Fatal Outcome; D005260:Female; D006261:Headache / Q000150:complications; D006801:Humans; D019586:Intracranial Hypertension / Q000188:drug therapy / Q000503:physiopathology; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D012851:Sinus Thrombosis, Intracranial / Q000000981:diagnostic imaging* / Q000188:drug therapy / Q000473:pathology; D014057:Tomography, X-Ray Computed; D014839:Vomiting / Q000150:complications
chemical_list: D000925:Anticoagulants