title: Performance of a self-expanding silicone stent in palliation of benign airway conditions.
abstract: BACKGROUND
  The Polyflex stent (Boston Scientific; Boston, MA) is a self-expanding, thin-walled, silicone stent. Its use has been described in the management of patients with malignant airway obstruction, yet reports of its use for treatment of benign airway conditions are rare.
  
  
  METHODS
  We report a retrospective review of our experience with the Polyflex stent in the management of benign airway conditions.
  
  
  RESULTS
  A total of 16 stents were deployed in 12 patients. The indications for the stent placement included the following: anastomotic stenosis following lung transplantation (LTR) [four patients]; tracheal stenosis (three patients); tracheobronchomalacia (two patients); tracheobronchopathiaosteochondroplastica (one patient); relapsing polychondritis (one patient); and bronchopleural fistula (one patient). Even though immediate palliation was established in most cases (90%), the incidence of complications was 75%. Stent migration was the most common consequence, with time to the event ranging from < 24 h to 7 months. One stent was expectorated within < 24 h. One patient coughed up a portion of the inner lining of the stent 7 months after its placement. Emergent bronchoscopy was required in four patients for mucous impaction. The complication rate was 100% in patients with LTR-related anastomotic stenosis.
  
  
  CONCLUSIONS
  The use of the Polyflex stent for the treatment of benign airway conditions is associated with a high complication rate. We have abandoned its use under such conditions in our practice.
authors.affiliation: Department of Pulmonary Allergy & Critical Care Medicine, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA.
authors.forename: Thomas R
authors.initials: TR
authors.lastname: Gildea
authors.forename: Sudish C
authors.initials: SC
authors.lastname: Murthy
authors.forename: Debashish
authors.initials: D
authors.lastname: Sahoo
authors.forename: David P
authors.initials: DP
authors.lastname: Mason
authors.forename: Atul C
authors.initials: AC
authors.lastname: Mehta
mesh_terms: D000328:Adult; D000368:Aged; D000402:Airway Obstruction / Q000209:etiology / Q000628:therapy*; D000714:Anastomosis, Surgical; D001983:Bronchial Fistula / Q000150:complications; D005260:Female; D006801:Humans; D016040:Lung Transplantation / Q000009:adverse effects; D008297:Male; D008875:Middle Aged; D010166:Palliative Care / Q000379:methods; D011081:Polychondritis, Relapsing / Q000150:complications; D012189:Retrospective Studies; D012828:Silicones; D015607:Stents / Q000009:adverse effects*; D014133:Tracheal Diseases / Q000150:complications; D014135:Tracheal Stenosis / Q000150:complications
chemical_list: D012828:Silicones