title: Antimicrobial activity of aqueous extracts of Larrea divaricata Cav (jarilla) against Helicobacter pylori.
abstract: We studied here the effect of aqueous extracts of Larrea divaricata Cav on the growth of Helicobacter pylori. Results show that cold extract, infusion, decoction and simulated digestion had inhibitory activity at 0.04-0.1 mg/l against clarithromycin and metronidazole susceptible and resistant H. pylori strains. These results support the popular use of L. divaricata Cav in gastric disturbances and prompt further research to characterize these compounds with a therapeutic potential against gastric ulcers and gastric cancer associated with H. pylori.
authors.affiliation: Area Microbiología, Departamento de Bioquímica y Ciencias Biológicas, Facultad de Química, Bioquímica y Farmacia, Universidad Nacional de San Luis. Chacabuco y Pedernera, 5700, San Luis, Argentina.
authors.forename: P W
authors.initials: PW
authors.lastname: Stege
authors.forename: R C
authors.initials: RC
authors.lastname: Davicino
authors.forename: A E
authors.initials: AE
authors.lastname: Vega
authors.forename: Y A
authors.initials: YA
authors.lastname: Casali
authors.forename: S
authors.initials: S
authors.lastname: Correa
authors.forename: B
authors.initials: B
authors.lastname: Micalizzi
mesh_terms: D024881:Drug Resistance, Bacterial; D016480:Helicobacter pylori / Q000187:drug effects*; D032442:Larrea / Q000737:chemistry*; D008826:Microbial Sensitivity Tests; D010936:Plant Extracts / Q000494:pharmacology
chemical_list: D010936:Plant Extracts