title: [Histone modification and regulation of chromatin function].
abstract: Nucleosomes play two main roles, acting as basal units in DNA compaction and coordinating most processes in chromosomes. The coordination is due to modification of histones, proteins forming nucleosomes. The review briefly describes the nucleosome structure and major modifications of histones and considers the role of such modifications in transcriptional suppression and activation.
authors.forename: D E
authors.initials: DE
authors.lastname: Koriakov
mesh_terms: D000107:Acetylation; D000595:Amino Acid Sequence; D000818:Animals; D002843:Chromatin / Q000235:genetics*; D019175:DNA Methylation; D006657:Histones / Q000235:genetics*; D006801:Humans; D008969:Molecular Sequence Data; D009707:Nucleosomes / Q000235:genetics; D034622:RNA Interference; D014158:Transcription, Genetic
chemical_list: D002843:Chromatin; D006657:Histones; D009707:Nucleosomes