[The effect of retrobulbar injection with anisodamine on ocular blood velocity in anterior ischemic optic neuropathy].
OBJECTIVE
To study the effect of retrobulbar injection with anisodamine on ocular blood velocity in anterior ischemic optic neuropathy (AION).


METHODS
15 minutes before injection, 15 minutes and 1 hour after injection, the blood flow velocity in 39 cases (39 eyes) diagnosed as AION was measured and analyzed by CDI, timed average maximum velocity, peak systolic velocity, end diastolic velocity, resistance index and pulsatility index of OA, CRA and PCA were recorded.


RESULTS
Compared with the normal eyes, each parameter of SPCA was statistically significant. 15 minutes and 1 hour after post ocular injection of anisodamine, every parameter examined in the experiment was increased except resistance index compared with pre-injection (P < 0.01).


CONCLUSIONS
retrobulbar injection with anisodamine can effectively improve flow velocity of nasal and tempo short posterior ciliary artery and central retinal artery.
Zhu
Xiao-qing
XQ
Beijing Tongren Ophthalmic Center, Capital University of Medical Sciences, Beijing 100730, China.
Tian
Bei
B
Yang
Wen-li
WL
Wei
Wen-bin
WB
Weng
Nai-qing
NQ
Wang
Lan
L
D000287:Administration, Topical; D000328:Adult; D000368:Aged; D001783:Blood Flow Velocity; D019842:Ciliary Arteries / Q000502:physiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D018917:Optic Neuropathy, Ischemic / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000503:physiopathology; D012161:Retinal Artery / Q000502:physiology; D012991:Solanaceous Alkaloids / Q000008:administration & dosage / Q000627:therapeutic use*; D018615:Ultrasonography, Doppler, Color; D014665:Vasodilator Agents / Q000008:administration & dosage / Q000627:therapeutic use*
D012991:Solanaceous Alkaloids; D014665:Vasodilator Agents; C003922:anisodamine