title: Enantioselective equilibration-access to chiral aldol adducts of mandelic acid esters.
abstract: [Structure: see text] Syn-configured aldol products of mandelic acid esters and aldehydes were synthesized by the catalytic use of amines in the presence of titanium(IV) tert-butoxide. Used along with chiral N-methylephedrine, anti-configured alpha,beta-dihydroxyesters were isolated with a high degree of enantioselectivity for the first time.
authors.affiliation: Humboldt-Universität zu Berlin, Institut für Chemie, Brook-Taylor Strasse 2, 12489 Berlin, Germany.
authors.forename: Stefan
authors.initials: S
authors.lastname: Scholtis
authors.forename: Andreas
authors.initials: A
authors.lastname: Ide
authors.forename: Rainer
authors.initials: R
authors.lastname: Mahrwald