Bone and lung metastases from intracranial meningioma.
Fifteen percent of intracranial tumors are represented by meningiomas. Meningioma is usually a benign neoplasm; malignant histology is rare and represents about 2-10% with a 43% incidence of metastasis. The most frequent site of metastasis is the lung and rare are other sites. There are no definitive criteria to predict the recurrence or metastases of meningioma and histological grading, according to WHO criteria, is the most important predictor of malignancy. A rare case of a woman with a relapse of intracranial meningioma in the right frontal lobe who subsequently developed simultaneous bone and intrapulmonary metastases is reported. According to these sites of metastases, it is suggested that in patients with a history of relapsed meningioma, a total body CT scan should be performed in order to investigate other possible sites of disease.
Fabi
Alessandra
A
Division of Medical Oncology A, Regina Elena National Cancer Institute, via Elio Chianesi 53, 00144 Rome, Italy. alessandra.fabi@virgilio.it
Nuzzo
Carmen
C
Vidiri
Antonello
A
Ciccarese
Mariangela
M
Felici
Alessandra
A
Cattani
Fabio
F
Cognetti
Francesco
F
D001859:Bone Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary*; D001932:Brain Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary*; D008279:Magnetic Resonance Imaging; D008579:Meningioma / Q000473:pathology*; D008875:Middle Aged; D014057:Tomography, X-Ray Computed