title: Appendicitis in pregnancy.
abstract: BACKGROUND
  Our urban practice had two incidences of documented appendicitis in pregnancy in a 24-hour period with two unique outcomes that prompted an inquiry. Appendicitis in pregnancy is relatively rare, but it has significant morbidity and is a cause of maternal and infant mortality. Abdominal pain is the most common presenting symptom, and the consideration of multiple pathologic disorders should be entertained. Accurate diagnosis of appendicitis in pregnancy is the largest challenge since the signs and symptoms may vary depending on the trimester in which the patient presents.
  
  
  METHODS
  We undertook a systematic review of English-language articles from 1975 to 2005 using the key words "appendicitis," and "pregnancy" using MEDLINE, CINAHL, and Cochrane Controlled Trials Register databases.
  
  
  CONCLUSIONS
  The accurate diagnosis of appendicitis during pregnancy requires a high level of suspicion and clinical skills, and not merely relying on the classic signs and diagnostic testing. Primary care providers play an important role in recognizing potential signs and symptoms of appendicitis in pregnancy to initiate prompt action and reduce negative maternal and fetal outcomes.
authors.affiliation: Department of Family Medicine, The State University of New York at Buffalo, Buffalo, NY 14215, USA. pastore3@buffalo.edu
authors.forename: Patricia A
authors.initials: PA
authors.lastname: Pastore
authors.forename: Dianne M
authors.initials: DM
authors.lastname: Loomis
authors.forename: John
authors.initials: J
authors.lastname: Sauret
mesh_terms: D000328:Adult; D001064:Appendicitis / Q000503:physiopathology*; D005260:Female; D006801:Humans; D011247:Pregnancy