title: Effects of disease severity on response to lateral wedged shoe insole for medial compartment knee osteoarthritis.
abstract: OBJECTIVE
  To determine the effects of lateral wedged insoles on knee kinetics and kinematics during walking, according to radiographic severity of medial compartment knee osteoarthritis (OA).
  
  
  METHODS
  A prospective case control study of patients with medial compartment OA of the knee.
  
  
  METHODS
  Gait analysis laboratory in a university hospital.
  
  
  METHODS
  Forty-six medial compartment knees with OA of 23 patients with bilateral disease and 38 knees of 19 age-matched healthy subjects as controls.
  
  
  METHODS
  Not applicable.
  
  
  METHODS
  We measured the peak external adduction moment at the knee during the stance phase of gait and the first acceleration peak after heel strike at the lateral side of the femoral condyles. Kellgren and Lawrence grading system was used for radiographic assessment of OA severity.
  
  
  RESULTS
  The mean value of peak external adduction moment of the knee was higher in OA knees than the control. Application of lateral wedged insoles significantly reduced the peak external adduction moment in Kellgren-Lawrence grades I and II knee OA patients. The first acceleration peak value after heel strike in these patients was relatively high compared with the control. Application of lateral wedged insoles significantly reduced the first acceleration peak in Kellgren-Lawrence grades I and II knee OA patients.
  
  
  CONCLUSIONS
  The kinetic and kinematic effects of wearing of lateral wedged insoles were significant in Kellgren-Lawrence grades I and II knee OA. The results support the recommendation of use of lateral wedged insoles for patients with early and mild knee OA.
authors.affiliation: Gait Analysis Laboratory, Division of Physical Therapy and Rehabilitation, Fukui University Hospital, Fukui, Japan. sshima@fmsrsa.fukui-med.ac.jp
authors.forename: Seiichiro
authors.initials: S
authors.lastname: Shimada
authors.forename: Shigeru
authors.initials: S
authors.lastname: Kobayashi
authors.forename: Makoto
authors.initials: M
authors.lastname: Wada
authors.forename: Kenzo
authors.initials: K
authors.lastname: Uchida
authors.forename: Shinichi
authors.initials: S
authors.lastname: Sasaki
authors.forename: Hideo
authors.initials: H
authors.lastname: Kawahara
authors.forename: Takafumi
authors.initials: T
authors.lastname: Yayama
authors.forename: Ippei
authors.initials: I
authors.lastname: Kitade
authors.forename: Kenta
authors.initials: K
authors.lastname: Kamei
authors.forename: Masafumi
authors.initials: M
authors.lastname: Kubota
authors.forename: Hisatoshi
authors.initials: H
authors.lastname: Baba
mesh_terms: D000368:Aged; D001696:Biomechanical Phenomena; D016022:Case-Control Studies; D005260:Female; D005684:Gait; D006801:Humans; D008297:Male; D009989:Orthotic Devices; D020370:Osteoarthritis, Knee / Q000503:physiopathology / Q000534:rehabilitation*; D011446:Prospective Studies; D012720:Severity of Illness Index; D012775:Shoes; D016138:Walking