title: [Influence of the depth of embryo transfer on pregnancy outcome in in vitro fertilization-embryo transfer].
abstract: OBJECTIVE
  To detect whether the depth of embryo transfer has influence on pregnancy outcome in in vitro fertilization-embryo transfer (IVF-ET).
  
  
  METHODS
  The distance between the high echogenic transfer dot and the fundal endometrium was measured under guidance of transabdominal ultrasound. The average distance 0.75 cm was used to divide patients into two groups. Group 1 included 44 patients with a distance > 0.75 cm, while group 2 had 48 patients with a distance </= 0.75 cm.
  
  
  RESULTS
  There were no significant differences in the average age (32 +/- 3 versus 31 +/- 4), the mean number of oocytes retrieved (14 +/- 7 versus 14 +/- 6), and the mean number of embryos transferred (2.3 +/- 0.6 versus 2.2 +/- 0.5) between groups 1 and 2. The distance to the fundal endometrium in group 2 was (0.50 +/- 0.21) cm, significantly smaller than that of group 1 (1.02 +/- 0.21) cm (P < 0.01). However, pregnancy rate was significantly higher (P < 0.05) in group 2 (58.3%, 28/48) than in group 1 (36.4%, 16/44). Although implantation rate in group 2 (33.0%, 35/106) was higher than group 1 (22.2%, 22/99), the difference was not significant.
  
  
  CONCLUSIONS
  Pregnancy outcome may be affected by the depth of embryo transfer, and the fundal endometrium is a favorable region for embryo deposition.
authors.affiliation: Reproductive Research Center, First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, China.
authors.forename: Jia
authors.initials: J
authors.lastname: Luo
authors.forename: Yan-wen
authors.initials: YW
authors.lastname: Xu
authors.forename: Can-quan
authors.initials: CQ
authors.lastname: Zhou
authors.forename: Cong
authors.initials: C
authors.lastname: Fang
authors.forename: Min-fang
authors.initials: MF
authors.lastname: Zhang
authors.forename: Guang-lun
authors.initials: GL
authors.lastname: Zhuang
mesh_terms: D000005:Abdomen / Q000000981:diagnostic imaging; D000328:Adult; D010064:Embryo Implantation; D004624:Embryo Transfer; D005260:Female; D005307:Fertilization in Vitro / Q000379:methods*; D006801:Humans; D011247:Pregnancy; D011256:Pregnancy Outcome; D018873:Pregnancy Rate; D012189:Retrospective Studies; D014463:Ultrasonography / Q000379:methods; D014599:Uterus / Q000000981:diagnostic imaging