Application of matrix solid-phase dispersion and liquid chromatography-mass spectrometry to fungicide residue analysis in fruits and vegetables.
A method based on matrix solid-phase dispersion (MSPD) and liquid chromatography-electrospay ionization-mass spectrometry used to analyze fifteen fungicide residues in fruits and vegetables is described. The method required only 0.5 g of sample, C(18)-bonded silica was used as dispersant sorbent, and ethyl acetate was used as eluting solvent. Fortified recoveries in apple, orange, banana, lettuce, grape and tomato samples ranged from 71% to 102% and relative standard deviations were less than 13% with fortified levels of 0.03-1.5 mg kg(-1). Detection and quantification limits were 1 approximately 30 microg kg(-1) and 4 approximately 100 microg kg(-1), respectively, with linear calibration curves extending up to 15 mg kg(-1). The analytical characteristics of MSPD compared very favorably with those found for a classical multiresidue method: the quick, easy, cheap, effective, rugged, and safe (QuEChERS) method. The method was applied to determine the fungicides in real samples. Liquid chromatography-tandem mass spectrometry (LC-MS-MS) was used as confirmatory tool for positive samples.
Wang
Suli
S
College of Science, China Agricultural University, Beijing, 100094, People's Republic of China.
Xu
Yanjun
Y
Pan
Canping
C
Jiang
Shuren
S
Liu
Fengmao
F
D002853:Chromatography, Liquid; D005506:Food Contamination / Q000032:analysis*; D005638:Fruit / Q000382:microbiology; D005659:Fungicides, Industrial / Q000032:analysis*; D013058:Mass Spectrometry; D014675:Vegetables / Q000382:microbiology
D005659:Fungicides, Industrial