title: The role of SPIO-enhanced MRI in the detection of malignant liver lesions.
abstract: The aim of this study was to evaluate the efficacy of superparamagnetic iron oxide (SPIO)-enhanced magnetic resonance imaging (MRI) in the detection of malignant liver tumors. MRI, using fast spin-echo T(2)-weighted and gradient-echo T(1)-weighted imagings before and after SPIO infusion, was performed in 32 patients with known or suspected hepatic lesions. Statistical analysis was performed using lesion-by-lesion analysis. SPIO-enhanced T(2)-weighted MRI showed results comparable to those of unenhanced T(2)-weighted MRI in the detection of focal liver lesions.
authors.affiliation: Department of Radiology, School of Medicine, Dokuz Eylul University, Izmir, Turkey.
authors.forename: Pelin
authors.initials: P
authors.lastname: Savranoglu
authors.forename: Funda
authors.initials: F
authors.lastname: Obuz
authors.forename: Sebnem
authors.initials: S
authors.lastname: Karasu
authors.forename: Ahmet
authors.initials: A
authors.lastname: Coker
authors.forename: Mustafa
authors.initials: M
authors.lastname: Secil
authors.forename: Ozgul
authors.initials: O
authors.lastname: Sagol
authors.forename: Enis
authors.initials: E
authors.lastname: Igci
authors.forename: Oguz
authors.initials: O
authors.lastname: Dicle
authors.forename: Ibrahim
authors.initials: I
authors.lastname: Astarcioglu
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000465:Algorithms; D003287:Contrast Media; D003911:Dextrans; D005260:Female; D052203:Ferrosoferric Oxide; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D007501:Iron; D008113:Liver Neoplasms / Q000175:diagnosis*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D058185:Magnetite Nanoparticles; D008297:Male; D008875:Middle Aged; D010087:Oxides; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity
chemical_list: D003287:Contrast Media; D003911:Dextrans; D058185:Magnetite Nanoparticles; D010087:Oxides; D007501:Iron; C065507:ferumoxides; D052203:Ferrosoferric Oxide