Paediatric aphakic glaucoma.
BACKGROUND
Aphakic glaucoma is a serious, sight-threatening complication in children who remain aphakic following congenital cataract surgery. The reported incidence varies from 15% to 45% and it has a higher incidence in small eyes and in babies who undergo surgery before 4 weeks of age. Most cases take the form of open-angle glaucoma. Despite careful monitoring, diagnostic difficulties in children may lead to delayed treatment. Aphakic children require ongoing monitoring, including examinations carried out under general anaesthesia.


RESULTS
Contrary to earlier optimism, it is unlikely, according to current clinical information, that intraocular lenses provide protection against the development of glaucoma. It is likely that the lower incidence of glaucoma in pseudophakic eyes results from selection bias for lens insertion. Both medical and surgical treatments have a role in glaucoma management. Trabeculectomy with mitomycin C or Seton implantation (glaucoma drainage device) form the mainstay of surgical treatment. The success rate with Seton implants is better in the short term and more promising in the longer term than that of trabeculectomy. Cyclodestructive procedures play a role in refractory glaucoma. Success rates for surgery range from 14% to 44% and many children require additional medical treatment. Children with aphakic glaucoma need lifelong care. Despite our best efforts, many have poor vision, poor glaucoma control and ultimately become blind.
Kirwan
Caitriona
C
Children's University Hospital, University College Dublin, Dublin, Ireland.
O'Keefe
Michael
M
D001036:Aphakia, Postcataract / Q000150:complications*; D001766:Blindness / Q000517:prevention & control; D002386:Cataract / Q000151:congenital; D002387:Cataract Extraction; D002675:Child, Preschool; D020327:Glaucoma Drainage Implants; D005902:Glaucoma, Open-Angle / Q000209:etiology* / Q000601:surgery; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D019654:Lens Implantation, Intraocular; D012307:Risk Factors; D014130:Trabeculectomy