Cholesterol, cholesterol-lowering agents/statins, and urologic disease: Part IV--is vitamin E phosphate or another unique type of this vitamin the last chance for these supplements?
Vitamin E, once the highly espoused heart healthy paradigm of the dietary supplement world, has now been touted by many experts to be either heart unhealthy or simply ineffective based on the results of past and recent randomized trials in cardiovascular medicine. Natural and synthetic vitamin E supplements, especially in large dosages, have been the concern. Researchers have embarked on testing a variety of other novel forms of vitamin E, such as vitamin E phosphate and other forms of vitamin E, to determine safety issues as well as the impact on cardiovascular disease (CVD) risk markers and end-points. Until vitamin E demonstrates meaningful changes in some of the accepted markers of CVD prevention, it will be difficult to espouse their use specifically for these and other conditions.
Moyad
Mark A
MA
Complementary Medicine, University of Michigan Medical Center, Department of Urology, Ann Arbor, MI, USA.
Robinson
Larry E
LE
D002318:Cardiovascular Diseases / Q000517:prevention & control*; D019587:Dietary Supplements; D006801:Humans; D014810:Vitamin E / Q000031:analogs & derivatives / Q000627:therapeutic use*
D014810:Vitamin E