Thrombophilias, perinatal stroke, and cerebral palsy.
Perinatal ischemic stroke has become recognized as a not-rare adverse outcome of pregnancy and a common cause of chronic neurologic disability in children. This review discusses the clinical entity, perinatal stroke, and its relationship to thrombophilias, inherited and acquired, and to maternal and pregnancy factors.
Nelson
Karin B
KB
National Institute of Neurological Disorders and Stroke, Bethesda, Maryland 20892-1447, USA. knelson@helix.nih.gov
D002545:Brain Ischemia / Q000209:etiology*; D002547:Cerebral Palsy / Q000209:etiology*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic; D011256:Pregnancy Outcome; D012307:Risk Factors; D020521:Stroke / Q000209:etiology; D019851:Thrombophilia / Q000150:complications*