Diuretic and analgesic effects of the methanol extract of Phoenix sylvestris root.
The analgesic and diuretic activities of the methanol extract of Phoenix sylvestris root on Swiss albino mice were observed. The extract showed significant (p<0.001) analgesic activity by reduction of percent inhibition of writhing induced by acetic acid (0.5% v/v) in 20.07% and 32.57% at a dose level of 150 mg/kg and 300-mg/kg body weights respectively. The methanol extract also showed diuretic effect at 1st hour of the study at 300-mg/kg and 2nd and 4th hour of the study at 150-mg/kg-body weight on swiss albino mice. The onset of diuretic effect was faster at a dose of 300-mg/kg body weights than 150 mg/kg body weight. The obtained results may give a clue for extensive phytochemical investigation of the plant for the development of herbal medicine.
Howlader
M A B
MA
Department of Pharmacology & Clinical Pharmacy, University of Dhaka, Dhaka 1000, Bangladesh.
Bachar
S C
SC
Begum
F
F
Rouf
A S S
AS
D000700:Analgesics / Q000494:pharmacology*; D000818:Animals; D004232:Diuretics / Q000494:pharmacology*; D005260:Female; D008297:Male; D051379:Mice; D010936:Plant Extracts / Q000494:pharmacology*; D018517:Plant Roots; D014197:Trees
D000700:Analgesics; D004232:Diuretics; D010936:Plant Extracts