title: Synthesis of plakortone B and analogs.
abstract: [Structure: see text] Use of a palladium-mediated alkoxycarbonylation/lactonization process provides a variable route to analogs of the plakortones. Four different analogs, including natural plakortone B, have been synthesized via this route.
authors.affiliation: Department of Chemistry, Frick Chemistry Laboratory, Princeton University, Princeton, New Jersey 08544, USA. mfshack@princeton.edu
authors.forename: M F
authors.initials: MF
authors.lastname: Semmelhack
authors.forename: Richard J
authors.initials: RJ
authors.lastname: Hooley
authors.forename: Christina M
authors.initials: CM
authors.lastname: Kraml
mesh_terms: D000818:Animals; D002384:Catalysis; D007783:Lactones / Q000138:chemical synthesis* / Q000378:metabolism; D015394:Molecular Structure; D010165:Palladium; D011161:Porifera / Q000378:metabolism
chemical_list: D007783:Lactones; C517066:plakortone B; D010165:Palladium