title: Ultrasound biomicroscopy in asymmetric pigment dispersion syndrome and pigmentary glaucoma.
abstract: OBJECTIVE
  To identify differences in anterior chamber anatomy among patients with asymmetric pigment dispersion syndrome and no other discernible cause for the asymmetry.
  
  
  METHODS
  Ultrasound biomicroscopy and A-scan biometry were performed on both eyes of 13 patients with asymmetric pigment dispersion syndrome without a known cause for asymmetric involvement. A radial perpendicular image in the horizontal temporal meridian detailing the scleral spur, angle anatomy, and iris configuration was obtained for each eye by 2 examiners.
  
  
  RESULTS
  There were no differences in lens thickness (P = .33), refractive error (P = .84), or axial length (P = .99) between more and less affected eyes. However, the mean +/- SD iris concavity (P<.001), iris-lens contact distance (P = .02), and distance from the scleral spur to the iris insertion (0.42 +/- 0.11 vs 0.29 +/- 0.06 mm) (P = .002) were greater in the more affected eye of each patient.
  
  
  CONCLUSIONS
  A more posterior iris insertion predisposes to the phenotypic expression of pigment dispersion syndrome.
authors.affiliation: Department of Ophthalmology, The New York Eye and Ear Infirmary, New York, NY 10003, USA.
authors.forename: Fabio N
authors.initials: FN
authors.lastname: Kanadani
authors.forename: Syril
authors.initials: S
authors.lastname: Dorairaj
authors.forename: Alan M
authors.initials: AM
authors.lastname: Langlieb
authors.forename: Wisam A
authors.initials: WA
authors.lastname: Shihadeh
authors.forename: Celso
authors.initials: C
authors.lastname: Tello
authors.forename: Jeffrey M
authors.initials: JM
authors.lastname: Liebmann
authors.forename: Robert
authors.initials: R
authors.lastname: Ritch
mesh_terms: D000328:Adult; D000867:Anterior Chamber / Q000000981:diagnostic imaging*; D017889:Exfoliation Syndrome / Q000000981:diagnostic imaging*; D005260:Female; D005902:Glaucoma, Open-Angle / Q000000981:diagnostic imaging*; D006801:Humans; D007429:Intraocular Pressure; D007498:Iris / Q000000981:diagnostic imaging*; D007908:Lens, Crystalline / Q000000981:diagnostic imaging; D008297:Male; D033401:Microscopy, Acoustic; D008875:Middle Aged