Efficient Friedel-Crafts alkylation of indoles and pyrrole with enones and nitroalkene in water.
An operationally simple and entirely green protocol for heteropoly acid (10 mg) catalyst conjugate addition of indoles and pyrrole to unsaturated carbonyl compounds and nitroalkene in water at ambient temperature in good to excellent yields has been developed.
Azizi
Najmedin
N
Organic Chemistry Laboratory, Chemistry & Chemical Engineering Research Center of Iran, PO Box 14335-186, Tehran, Iran.
Arynasab
Fezzeh
F
Saidi
Mohammad R
MR