title: Impact of influenza vaccination on major cause-specific mortality.
abstract: The efficacy of influenza vaccination is not well understood for major cause-specific mortality except pneumonia. For 10 months we followed the mortality data of 35,637 vaccinated elderly (>65 years old) in a county with 102,698 elderly in southern Taiwan. A multivariate Cox model showed that vaccination was significantly associated with lower mortality for all causes, [hazards ratio (HR)=0.56], stroke (HR=0.35), renal disease (HR=0.40), diabetes mellitus (HR=0.45), pneumonia (HR=0.47), COPD (HR=0.55), malignancy (HR=0.74), and heart diseases (HR=0.78), p<0.05. Influenza vaccination was strongly associated with reducing major cause-specific mortality.
authors.affiliation: Community Medicine Research Centre and Institute of Public Health, National Yang-Ming University, Taipei, Taiwan.
authors.forename: Chong-Shan
authors.initials: CS
authors.lastname: Wang
authors.forename: Shan-Tair
authors.initials: ST
authors.lastname: Wang
authors.forename: Ching-Te
authors.initials: CT
authors.lastname: Lai
authors.forename: Li-Jen
authors.initials: LJ
authors.lastname: Lin
authors.forename: Pesus
authors.initials: P
authors.lastname: Chou
mesh_terms: D000368:Aged; D000704:Analysis of Variance; D005260:Female; D006801:Humans; D007252:Influenza Vaccines / Q000627:therapeutic use*; D007251:Influenza, Human / Q000401:mortality* / Q000517:prevention & control*; D008297:Male; D016016:Proportional Hazards Models; D012307:Risk Factors; D013624:Taiwan / Q000453:epidemiology; D016896:Treatment Outcome; D014611:Vaccination / Q000706:statistics & numerical data*
chemical_list: D007252:Influenza Vaccines