Structures of new cucurbitane-type triterpenes and glycosides, karavilagenins and karavilosides, from the dried fruit of Momordica charantia L. in Sri Lanka.
Three new cucurbitane-type triterpene called karavilagenins A, B, and C and five new cucurbitane-type triterpene glycosides called karavilosides I, II, III, IV, and V were isolated from the dried fruit of Sri Lanka Momordica charantia L. (Cucurbitaceae) together with two known cucurbitane-type triterpenes, 19(R)-methoxy-5beta,19-epoxycucurbita-6,23-dien-3beta,25-diol and 5,19-epoxycucurbita-6,23-diene-3,25-diol, and nine known cucurbitane-type triterpene glycosides, goyaglycosides-b, -c, and -d, and momordicosides F1, F2, G, I, K, and L. The structures of karavilagenins and karavilosides were elucidated on the basis of chemical and physicochemical evidence.
Nakamura
Seikou
S
Kyoto Pharmaceutical University, Misasagi, Kyoto, Japan.
Murakami
Toshiyuki
T
Nakamura
Junko
J
Kobayashi
Hisanori
H
Matsuda
Hisashi
H
Yoshikawa
Masayuki
M
D005638:Fruit / Q000737:chemistry*; D006027:Glycosides / Q000737:chemistry* / Q000302:isolation & purification; D008968:Molecular Conformation; D029777:Momordica charantia / Q000737:chemistry*; D013188:Sri Lanka; D013237:Stereoisomerism; D014315:Triterpenes / Q000737:chemistry* / Q000302:isolation & purification
D006027:Glycosides; D014315:Triterpenes; C514277:cucurbitane; C516642:karavilagenin A; C516639:karavilagenin B; C516641:karaviloside I; C516640:karaviloside II