title: Rhizobium etli USDA9032 engineered to produce a phenazine antibiotic inhibits the growth of fungal pathogens but is impaired in symbiotic performance.
abstract: Phenazine production was engineered in Rhizobium etli USDA9032 by the introduction of the phz locus of Pseudomonas chlororaphis O6. Phenazine-producing R. etli was able to inhibit the growth of Botrytis cinerea and Fusarium oxysporum in vitro. Black bean inoculated with phenazine-producing R. etli produced brownish Fix(-) nodules.
authors.affiliation: Plant Genetics Research Unit, United States Department of Agriculture-Agricultural Research Service, 108W Curtis Hall, University of Missouri, Columbia, MO 65211, USA. KrishnanH@missouri.edu
authors.forename: Hari B
authors.initials: HB
authors.lastname: Krishnan
authors.forename: Beom Ryong
authors.initials: BR
authors.lastname: Kang
authors.forename: Ammulu
authors.initials: A
authors.lastname: Hari Krishnan
authors.forename: Kil Yong
authors.initials: KY
authors.lastname: Kim
authors.forename: Young Cheol
authors.initials: YC
authors.lastname: Kim
mesh_terms: D000900:Anti-Bacterial Agents / Q000378:metabolism* / Q000494:pharmacology; D020171:Botrytis / Q000235:genetics / Q000254:growth & development; D007887:Fabaceae / Q000382:microbiology; D005658:Fungi / Q000254:growth & development* / Q000472:pathogenicity; D005670:Fusarium / Q000235:genetics / Q000254:growth & development; D005818:Genetic Engineering / Q000379:methods*; D010572:Pest Control, Biological / Q000379:methods; D010619:Phenazines / Q000378:metabolism* / Q000494:pharmacology; D042163:Rhizobium etli / Q000187:drug effects / Q000235:genetics* / Q000254:growth & development / Q000378:metabolism; D013559:Symbiosis / Q000187:drug effects
chemical_list: D000900:Anti-Bacterial Agents; D010619:Phenazines