title: Pinch-off syndrome in patients with sickle cell disease receiving erythrocytapheresis.
abstract: A 6-year-old female with homozygous sickle cell disease had a central venous access device (CVAD) placed to facilitate chronic erythrocytapheresis. Erythrocytapheresis was ineffective due to the rare pinch-off syndrome causing communication between the dual lumen tubing. Awareness of and monitoring for the pinch-off syndrome is indicated in people with sickle cell disease and a CVAD for chronic erythrocytapheresis.
authors.affiliation: Department of Pediatric Hematology, The Children's Hospital and the University of Colorado at Denver Health Sciences Center, Denver, Colorado, USA. nuss.rachelle@tchden.org
authors.forename: Rachelle
authors.initials: R
authors.lastname: Nuss
authors.forename: Laura
authors.initials: L
authors.lastname: Cole
authors.forename: Tuan
authors.initials: T
authors.lastname: Le
authors.forename: Edmund
authors.initials: E
authors.lastname: Orsini
authors.forename: Roger
authors.initials: R
authors.lastname: Harned
mesh_terms: D000755:Anemia, Sickle Cell / Q000097:blood / Q000628:therapy*; D001781:Blood Component Removal; D002405:Catheterization, Central Venous; D002408:Catheters, Indwelling; D002648:Child; D017707:Erythrocyte Transfusion; D005260:Female; D006801:Humans; D013350:Subclavian Vein