Ovarian sclerosing stromal tumor presenting as Meigs' syndrome with elevated CA-125.
Meigs' syndrome caused by sclerosing stromal tumor is extremely rare and only two cases have been reported to date. An elevated serum level of CA-125 is also unusual and it has been thought that it is the consequence of physical irritation and inflammation. In this report, we present the case of a 50-year-old postmenopausal woman with a sclerosing stromal tumor presenting with Meigs' syndrome and an elevated CA-125 level (1476.8 IU/mL). This case highlights the difficulty in discerning the diagnosis of Meigs' syndrome from that of an ovarian malignancy and it should be considered in the differential diagnosis in postmenopausal patients with pelvic mass, ascites, pleural effusions and elevated serum CA-125.
Jung
Nan Hee
NH
Department of Obstetrics and Gynecology, College of Medicine, Korea University, Kyounggi-do, Korea.
Kim
Tak
T
Kim
Hai Joong
HJ
Lee
Kyu Wan
KW
Lee
Nak Woo
NW
Lee
Eung Seok
ES
D018394:CA-125 Antigen / Q000097:blood*; D003937:Diagnosis, Differential; D005260:Female; D006651:Histocytochemistry; D006801:Humans; D008539:Meigs Syndrome / Q000097:blood / Q000150:complications / Q000175:diagnosis / Q000209:etiology*; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology; D010996:Pleural Effusion; D017698:Postmenopause; D011859:Radiography; D018312:Sex Cord-Gonadal Stromal Tumors / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology
D018394:CA-125 Antigen