title: Cranial neuropathy and bone involvement in primary systemic amyloidosis.
abstract: Bone involvement in primary systemic amyloidosis is rare. Intracranial involvement in primary amyloidosis has not been reported so far. We report two cases of bone involvement in primary amyloidosis. The first patient also had combined deficiencies of factor IX and XII, while the second patient had associated intracranial involvement and XIIth cranial nerve palsy. Both these cases are unique in that, destructive bone lesions with intracranial involvement and combined factor deficiencies have not been reported in primary amyloidosis previously.
authors.affiliation: Internal Medicine, Amrita Institute of Medical Sciences and Research Centre, Elamakkara, Kerala.
authors.forename: S
authors.initials: S
authors.lastname: Ray
authors.forename: K
authors.initials: K
authors.lastname: Pavithran
authors.forename: P S
authors.initials: PS
authors.lastname: Nair
mesh_terms: D000328:Adult; D000368:Aged; D000686:Amyloidosis / Q000150:complications*; D001847:Bone Diseases / Q000188:drug therapy / Q000209:etiology*; D003389:Cranial Nerve Diseases / Q000188:drug therapy / Q000209:etiology*; D003907:Dexamethasone / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007372:Interferons / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged
chemical_list: D003907:Dexamethasone; D007372:Interferons