[Genomic imprinting: a case of inherited hematocrit, radiosensitivity, and antioxidant status in human being, as well as weight of newborn mammals].
Epigenetic hypothesis of dynamic genomic parental imprinting, explaining the mechanisms of formation and inheritance of quantitative characters in multicellular organisms, is proposed. Method for analyzing the compliance of quantitative characters of organisms with the hypothesis of dynamic genomic parental imprinting is developed. Examples of human characters and characters of other mammals inherited in accordance with the proposed model are given. It is concluded that the hypothesis can be used for studying ontogeny and explaining the mechanisms of inheritance of the morphoses providing the stability and evolution of species. Possible ways of further experimental verification of the hypothesis and areas of its practical application are discussed.
Kutmin
A I
AI
D000818:Animals; D000975:Antioxidants / Q000378:metabolism*; D001724:Birth Weight / Q000235:genetics*; D018392:Genomic Imprinting; D006400:Hematocrit; D006801:Humans; D008957:Models, Genetic; D011836:Radiation Tolerance / Q000235:genetics*
D000975:Antioxidants