Metabolic and morphologic complications of HIV infection.
In the era of highly active antiretroviral therapy, long-term complications of HIV infection and antiretroviral therapy deserve heightened attention. Morphologic and metabolic complications seen during the course of HIV infection encompass a variety of entities that may share a common pathophysiologic pathway. This review article will discuss clinical syndromes such as wasting, lipoatrophy/lipohypertrophy, polymetabolic syndrome as well as hyperlipidemia, cardiovascular disease, lactic acidosis, and metabolic bone disease in HIV-infected patients.
Eid
Albert J
AJ
Mayo Clinic College of Medicine, Rochester, MN, USA. eid.albert@mayo.edu
Orenstein
Robert
R
D001847:Bone Diseases / Q000175:diagnosis / Q000209:etiology; D002318:Cardiovascular Diseases / Q000175:diagnosis / Q000209:etiology; D050171:Dyslipidemias / Q000175:diagnosis / Q000209:etiology; D015658:HIV Infections / Q000150:complications* / Q000503:physiopathology; D019247:HIV Wasting Syndrome / Q000175:diagnosis* / Q000209:etiology; D039682:HIV-Associated Lipodystrophy Syndrome / Q000175:diagnosis / Q000209:etiology; D006801:Humans; D008659:Metabolic Diseases / Q000175:diagnosis* / Q000209:etiology