[Clinical and pathological analysis of choroidal metastatic carcinoma].
OBJECTIVE
To study the clinical and pathological characteristics of choroidal metastatic carcinoma.


METHODS
The clinical data, pathological character, primary tumor origin and histological classification of 18 patients with choroidal metastatic carcinoma were analyzed retrospectively.


RESULTS
Most patients had severe visual impairment. Solid mass was seen in the posterior pole of the eyes in all 18 patients through ocular fundus examination, 8 cases had retinal detachment. B scan and CT examination found flat or irregular masses. MRI examination had been performed on 5 patients, high signal intensities on T1W and low signal intensities on T2W were found. Five patients were adenocarcinoma, 4 were squamous carcinoma and 3 were undifferentiated carcinoma through pathological examination. Primary tumor was lung carcinoma in 10 cases (55%) and breast carcinoma in 4 cases (22%).


CONCLUSIONS
Rapid decrease of visual acuity, flat neoplasm in ocular fundus and secondary retinal detachment are the main clinical characteristics of choroidal metastatic carcinoma. The most common primary tumor is lung carcinoma and the most common histopathological classification is adenocarcinoma. Imaging examination is helpful for the diagnosis of choroidal metastatic carcinoma.
Niu
Ying-jun
YJ
Department of Ophthalmology, Affiliated Hospital of the Medical School of Qingdao University, Qingdao 266003, China. niuyingjun@yahoo.com.cn
Liu
Fu-ling
FL
Zhou
Zhan-yu
ZY
Wang
Yun-xiao
YX
Kang
Ju
J
D000328:Adult; D000368:Aged; D018567:Breast Neoplasms, Male / Q000473:pathology; D002830:Choroid Neoplasms / Q000175:diagnosis* / Q000503:physiopathology / Q000556:secondary*; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009362:Neoplasm Metastasis; D012189:Retrospective Studies; D014792:Visual Acuity