Functionalized oxepines via fragmentation of highly strained epoxides.
[Structure: see text] Epoxidation of highly strained cyclobutenes followed by thermal rearrangement provides a new entry into oxepine-containing bicyclo[5.3.0] ring systems. In contrast to the rearrangement of the corresponding cyclopropanated systems, the strained epoxides in this study are believed to fragment through two competing pathways leading to a mixture of diastereomeric 5-7 ring systems.
Leyhane
Andrew J
AJ
Department of Chemistry, Merkert Chemistry Center, Boston College, 2609 Beacon Street, Chestnut Hill, Massachusetts 02467, USA.
Snapper
Marc L
ML
D004852:Epoxy Compounds / Q000737:chemistry*; D015394:Molecular Structure
D004852:Epoxy Compounds