[Biophysical and biochemical intrapartum fetal assessment in relation to hematological varaiables in umbilical cord blood].
The analysis of the hematological variables of umbilical cord blood can be useful in broadening our knowledge of both physiological and pathological processes undergoing during prenatal period.


OBJECTIVE
The aim of our study was to evaluate the hematological parameters of umbilical cord blood in cases of either the abnormal fetal heart rate or the confirmed fetal acidosis.


METHODS
A study group consisted of 458 neonates, live-born term of 38 to 41 completed weeks of single gestation. In each case, the hematological cord blood parameters were assessed. Fetal acidosis was diagnosed when the umbilical cord blood pH was below 7,15. Fetal heart rate (FHR) was assessed according to FIGO criteria. Statistical analysis was conducted using Mann-Withney tests, analysis of variance, p-value < 0.05 was considered as significant.


RESULTS
The values of WBC (16,5 vs. 13,8x109), NRBC (25,1 vs. 7,3 /100 WBC) and HCT (51,8 vs. 46,5%) were higher in cases of fetus acidosis compare to non-acidemic fetuses. The significant differences in RBC, PLT, NRBC, HCT, HG were observed between group with abnormal and normal FHR.


CONCLUSIONS
Fetal distress resulted in significant changes of the hematological variables in umbilical cord blood. Fetal hemopoetic system responds in specific manner to asphyxia. A precise analysis of fetal hematological variables may help to establish an exact onset and degree of fetal hypoxia.
Redźko
Sławomir
S
Klinika Perinatologii Akademii Medycznej w Białymstoku. redzkosl@amb.edu.pl
Przepieść
Jerzy
J
Zak
Janusz
J
Wysocka
Jolanta
J
Urban
Jan
J
D000328:Adult; D001774:Blood Chemical Analysis; D015331:Cohort Studies; D005260:Female; D005312:Fetal Blood / Q000737:chemistry*; D005316:Fetal Distress / Q000097:blood* / Q000175:diagnosis; D005311:Fetal Hypoxia / Q000097:blood* / Q000175:diagnosis; D005323:Fetal Monitoring / Q000379:methods; D006801:Humans; D007231:Infant, Newborn; D007743:Labor, Obstetric / Q000097:blood*; D011247:Pregnancy; D012016:Reference Values; D018709:Statistics, Nonparametric