title: [Lithium-induced encephalopathy mimicking Creutzfeldt-Jakob disease].
abstract: BACKGROUND
  Creutzfeldt-Jakob disease (CJD) has a poor prognosis. Certain clinical presentations can be suggestive yet mimic a curable disease.
  
  
  METHODS
  In the present study, we report the case of a 67-year-old man with a one-month history of progressive dementia, with myoclonic jerks and cerebellar syndrome suggesting a diagnosis of Creutzfeldt-Jakob encephalopathy. He had been treated for 9 years with lithium for a bipolar disorder. The results of the different investigations and the favorable course after discontinuation of lithium were in favor of the diagnosis of drug-induced Creutzfeldt-Jakob syndrome.
  
  
  CONCLUSIONS
  This case illustrates the importance for researching a curable etiology in presence of clinical features suggesting a CJD.
authors.affiliation: Service de Neurologie et Pathologie du Mouvement, EA 2683, Hôpital Roger Salengro, rue du Professeur Emile Laine, CHRU, 59037 Lille Cedex.
authors.forename: S
authors.initials: S
authors.lastname: Mouldi
authors.forename: E
authors.initials: E
authors.lastname: Le Rhun
authors.forename: S
authors.initials: S
authors.lastname: Gautier
authors.forename: M
authors.initials: M
authors.lastname: Devemy
authors.forename: A
authors.initials: A
authors.lastname: Destée
authors.forename: L
authors.initials: L
authors.lastname: Defebvre
mesh_terms: D000368:Aged; D018692:Antimanic Agents / Q000009:adverse effects*; D001927:Brain Diseases / Q000175:diagnosis* / Q000188:drug therapy*; D007562:Creutzfeldt-Jakob Syndrome / Q000175:diagnosis*; D003937:Diagnosis, Differential; D004569:Electroencephalography; D005260:Female; D006801:Humans; D018021:Lithium Chloride / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged
chemical_list: D018692:Antimanic Agents; D018021:Lithium Chloride