Shiga toxin and Shiga toxin-encoding phage do not facilitate Escherichia coli O157:H7 colonization in sheep.
Isogenic strains of Escherichia coli O157:H7, missing either stx(2) or the entire Stx2-encoding phage, were compared with the parent strain for their abilities to colonize sheep. The absence of the phage or of the Shiga toxin did not significantly impact the magnitude or duration of shedding of E. coli O157:H7.
Cornick
Nancy A
NA
Department of Veterinary Microbiology and Preventative Medicine, 2130 Vet Med Building, Iowa State University, Ames, IA 50010, USA. ncornick@iastate.edu
Helgerson
Amy F
AF
Sharma
Vijay
V
D000818:Animals; D003090:Coliphages / Q000235:genetics* / Q000378:metabolism; D015169:Colony Count, Microbial; D019453:Escherichia coli O157 / Q000235:genetics / Q000254:growth & development* / Q000821:virology; D005243:Feces / Q000382:microbiology; D017353:Gene Deletion; D012756:Sheep / Q000382:microbiology*; D022641:Shiga Toxin 2 / Q000235:genetics* / Q000378:metabolism*
D022641:Shiga Toxin 2