Mechanical properties and biocompatibility of soluble eggshell membrane protein/poly(vinyl alcohol) blend films.
Poly(vinyl alcohol) (PVA) has been blended with soluble eggshell membrane protein (SEP) to improve the mechanical properties of SEP film that is brittle. Tensile strength and elongation-at-break increase with increasing amount of PVA. When the SEP/PVA proportion is 1:1, a strong and flexible film is obtained, having a tensile strength of 22.7 MPa and elongation-at-break of 106%. Although scanning electron microscopy observation of the freeze-fractured cross-section shows microphase separation, interaction between SEP and PVA exists, as revealed by FT-IR. NIH3T3 cell culture demonstrates that SEP/PVA blend films with up to 50% of PVA show biocompatibility comparable to pure SEP film.
Yi
Feng
F
Institute of Polymer Science and Engineering, Department of Chemical Engineering, School of Materials Science and Engineering, Tsinghua University, Beijing 100084, P R. China.
Lu
Jian-Wei
JW
Guo
Zhao-Xia
ZX
Yu
Jian
J
D016475:3T3 Cells; D000818:Animals; D001672:Biocompatible Materials / Q000737:chemistry* / Q000494:pharmacology; D002152:Calorimetry, Differential Scanning; D049109:Cell Proliferation / Q000187:drug effects; D004527:Egg Proteins / Q000737:chemistry*; D008567:Membranes, Artificial; D051379:Mice; D008855:Microscopy, Electron, Scanning; D008858:Microscopy, Phase-Contrast; D011142:Polyvinyl Alcohol / Q000737:chemistry*; D017550:Spectroscopy, Fourier Transform Infrared; D013718:Tensile Strength; D014961:X-Ray Diffraction
D001672:Biocompatible Materials; D004527:Egg Proteins; D008567:Membranes, Artificial; D011142:Polyvinyl Alcohol