Budesonide combined with ursodeoxycholic acid in primary biliary cirrhosis with advanced liver damage.
We describe two patients with primary biliary cirrhosis who rapidly suffered progressive liver failure and developed jaundice, despite having undergone correct therapy using ursodeoxycholic acid. Both cases showed an extraordinary clinical and biochemical response 2 months after budesonide was added to standard therapy, leading to recovery of normal liver function.
Pagán
B
B
Medicine Department, University Hospital La Paz, P° Castellana 261, 280046, Madrid, Spain.
Erdozain
J C
JC
Comas
C
C
Martín-Chávarri
S
S
López
M
M
Gómez-Cerezo
J F
JF