Mechanical control of enantioselectivity of amino acid recognition by cholesterol-armed cyclen monolayer at the air-water interface.
Monolayers of the cholesterol-armed cyclen Na+ complex at the air-water interface display a remarkable, surface pressure dependent enantioselectivity of amino acid recognition. Upon compression of the monolayer, the binding constants of amino acids increase accompanying an inversion of chiral selectivity from the d- to l-form in the case of valine.
Michinobu
Tsuyoshi
T
National Institute for Materials Science (NIMS), 1-1 Namiki, Tsukuba 305-0044, Japan. tmichi@cc.tuat.ac.jp
Shinoda
Satoshi
S
Nakanishi
Takashi
T
Hill
Jonathan P
JP
Fujii
Kazuko
K
Player
Tomoko N
TN
Tsukube
Hiroshi
H
Ariga
Katsuhiko
K
D000388:Air; D000596:Amino Acids / Q000737:chemistry*; D002784:Cholesterol / Q000737:chemistry*; D000080027:Cyclams; D006571:Heterocyclic Compounds / Q000737:chemistry*; D017550:Spectroscopy, Fourier Transform Infrared; D013237:Stereoisomerism; D014867:Water / Q000737:chemistry*
D000596:Amino Acids; D000080027:Cyclams; D006571:Heterocyclic Compounds; D014867:Water; C038072:cyclen; D002784:Cholesterol