title: Influence of wall teichoic acid on lysozyme resistance in Staphylococcus aureus.
abstract: Staphylococcus aureus peptidoglycan (PG) is completely resistant to the hydrolytic activity of lysozyme. Here we show that modifications in PG by O acetylation, wall teichoic acid, and a high degree of cross-linking contribute to this resistance.
authors.affiliation: Microbial Genetics, University of Tübingen, 72076 Tübingen, Germany.
authors.forename: Agnieszka
authors.initials: A
authors.lastname: Bera
authors.forename: Raja
authors.initials: R
authors.lastname: Biswas
authors.forename: Silvia
authors.initials: S
authors.lastname: Herbert
authors.forename: Emir
authors.initials: E
authors.lastname: Kulauzovic
authors.forename: Christopher
authors.initials: C
authors.lastname: Weidenmaier
authors.forename: Andreas
authors.initials: A
authors.lastname: Peschel
authors.forename: Friedrich
authors.initials: F
authors.lastname: Götz
mesh_terms: D000107:Acetylation / Q000187:drug effects; D002473:Cell Wall / Q000737:chemistry; D024881:Drug Resistance, Bacterial; D006868:Hydrolysis / Q000187:drug effects; D009113:Muramidase / Q000378:metabolism / Q000494:pharmacology*; D010457:Peptidoglycan / Q000302:isolation & purification / Q000378:metabolism; D013211:Staphylococcus aureus / Q000737:chemistry / Q000187:drug effects*; D013682:Teichoic Acids / Q000737:chemistry / Q000378:metabolism*
chemical_list: D010457:Peptidoglycan; D013682:Teichoic Acids; D009113:Muramidase