title: Fully automated continuous flow synthesis of 4,5-disubstituted oxazoles.
abstract: [Structure: see text] A multipurpose mesofluidic flow reactor capable of producing gram quantities of material has been developed as an automated synthesis platform for the rapid on-demand synthesis of key building blocks and small exploratory libraries. The reactor is configured to provide the maximum flexibility for screening of reaction parameters that incorporate on-chip mixing and columns of solid supported reagents to expedite the chemical syntheses.
authors.affiliation: Innovative Technology Center (ACS), Department of Chemistry, University of Cambridge, Cambridge, UK, CB2 1EW.
authors.forename: Marcus
authors.initials: M
authors.lastname: Baumann
authors.forename: Ian R
authors.initials: IR
authors.lastname: Baxendale
authors.forename: Steven V
authors.initials: SV
authors.lastname: Ley
authors.forename: Christoper D
authors.initials: CD
authors.lastname: Smith
authors.forename: Geoffrey K
authors.initials: GK
authors.lastname: Tranmer