title: Viral enzymes.
abstract: Viral genomes show unequalled diversity, ranging from single-stranded DNA to double-stranded RNA. Moreover, viruses can quickly adapt to the host's immune response and drug treatment. Although they tend to make optimal use of the host cell's reservoir of proteins, viruses need to carry some enzymatic functions with them, as they may not be available or accessible in the infected cell. Recently, progress has been made in our structural understanding of viral enzymes involved in all stages of the viral life cycle, which includes entry, hijack, replication and exit stages.
authors.affiliation: Institute of Biochemistry, Center for Structural and Cell Biology in Medicine, University of Lübeck, Ratzeburger Allee 160, 23538 Lübeck, Germany.
authors.forename: Jeroen R
authors.initials: JR
authors.lastname: Mesters
authors.forename: Jinzhi
authors.initials: J
authors.lastname: Tan
authors.forename: Rolf
authors.initials: R
authors.lastname: Hilgenfeld
mesh_terms: D004261:DNA Replication; D008958:Models, Molecular; D011487:Protein Conformation; D014764:Viral Proteins / Q000737:chemistry / Q000378:metabolism; D018406:Virus Physiological Phenomena; D014779:Virus Replication; D014780:Viruses / Q000201:enzymology* / Q000235:genetics / Q000472:pathogenicity
chemical_list: D014764:Viral Proteins