Novel therapies for meningiomas.
Although advances in surgery, radiation therapy and stereotactic radiosurgery have significantly improved the treatment of meningiomas, there remains an important subset of patients who remain refractory to conventional therapy. Treatment with chemotherapeutic agents such as hydroxyurea and alpha-interferon has provided minimal benefit. In this review, the role of newly emerging novel therapies for meningiomas, with a focus on targeted molecular agents, will be discussed.
Wen
Patrick Y
PY
Center for Neuro-Oncology Dana-Farber/Brigham and Women's Cancer Center, and Division of Neuro-Oncology, Department of Neurology, Brigham and Women's Hospital, Boston, MA 02115, USA. pwen@partners.org
Drappatz
Jan
J
D006801:Humans; D008577:Meningeal Neoplasms / Q000188:drug therapy* / Q000235:genetics* / Q000601:surgery / Q000628:therapy; D008579:Meningioma / Q000188:drug therapy* / Q000235:genetics* / Q000601:surgery / Q000628:therapy