title: Effects of spirulina on the number of ovary mast cells in lead-induced toxicity in rats.
abstract: The present study investigated the protective effect of Spirulina against the lead-induced increase in mast cells in the ovary during the oestrous cycle of rats. In the ovary cortex and medulla of lead-exposed animals, there was a significant increase in the number of mast cells; however, when also treated with Spirulina, a decrease was observed. The number of mast cells when Spirulina (300 mg/kg) was used alone was not significantly different from that of the control group. These results indicate that Spirulina decreases the number of mast cells induced by lead in the cortex and medulla of rat ovary.
authors.affiliation: University of Yüzüncü Yil, Faculty of Veterinary Medicine, Department of Histology and Embryology, Kampüs, 65080, Van, Turkey. turankaraca74@hotmail.com
authors.forename: Turan
authors.initials: T
authors.lastname: Karaca
authors.forename: Nejdet
authors.initials: N
authors.lastname: Simşek
mesh_terms: D000818:Animals; D000975:Antioxidants / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D004781:Environmental Exposure / Q000009:adverse effects; D004971:Estrus; D005260:Female; D007854:Lead / Q000633:toxicity*; D008407:Mast Cells / Q000166:cytology / Q000187:drug effects*; D010053:Ovary / Q000166:cytology / Q000187:drug effects*; D008517:Phytotherapy; D010936:Plant Extracts / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D051381:Rats; D017208:Rats, Wistar; D053545:Spirulina
chemical_list: D000975:Antioxidants; D010936:Plant Extracts; D007854:Lead