title: [Characterization of platelets aggregation inhibitor from Agkistrodon blomhoffii ussuriensis snake venom].
abstract: Platelet aggregation inhibitor--"Blomus-B" from Agkistrodon blomhoffii ussuriensis venom has been isolated by affinity and ion-exchange chromatography. The purified inhibitor is a novel non-enzymatic single-chain protein with molecular weigth of 13 kDa. "Blomus-B" causes a change of platelets shape and takes effect on ADP- and adrenalin-induced platelet aggregation.
authors.forename: V L
authors.initials: VL
authors.lastname: Karbovs'kyĭ
authors.forename: O M
authors.initials: OM
authors.lastname: Savchuk
authors.forename: H L
authors.initials: HL
authors.lastname: Volkov
authors.forename: N V
authors.initials: NV
authors.lastname: Zaichko
authors.forename: Ts
authors.initials: Ts
authors.lastname: Bykhan
mesh_terms: D017836:Agkistrodon; D000818:Animals; D002850:Chromatography, Gel; D003435:Crotalid Venoms / Q000737:chemistry*; D066298:In Vitro Techniques; D008970:Molecular Weight; D010974:Platelet Aggregation / Q000187:drug effects*; D010975:Platelet Aggregation Inhibitors / Q000302:isolation & purification / Q000494:pharmacology; D011817:Rabbits; D013997:Time Factors
chemical_list: C031442:Agkistrodon venoms; D003435:Crotalid Venoms; D010975:Platelet Aggregation Inhibitors