Daytime pulse oximeter measurements do not predict incidence of pain and acute chest syndrome episodes in sickle cell anemia.
A prospective, infant cohort study of children with sickle cell anemia was evaluated to determine the relationship between daytime pulse oximeter measurements and the incidence of pain and acute chest episodes (ACS). A total of 130 children were evaluated. The Pearson correlation between SpO2 and pain and ACS episode rates were 0.00 (P = .97) and 0.10 (P = .27), respectively. Daytime SpO2 cannot independently predict the subsequent rate of pain and ACS episodes.
Uong
Elizabeth C
EC
Department of Pediatrics, Division of Allergy and Pulmonary Medicine and Division of Genetics, Washington University School of Medicine, St. Louis, MO 63108, USA.
Boyd
Jessica Henderson
JH
DeBaun
Michael R
MR
D000208:Acute Disease; D000293:Adolescent; D000755:Anemia, Sickle Cell / Q000150:complications* / Q000503:physiopathology*; D015415:Biomarkers / Q000097:blood; D002637:Chest Pain / Q000209:etiology* / Q000503:physiopathology; D002648:Child; D002675:Child, Preschool; D002940:Circadian Rhythm; D005260:Female; D005500:Follow-Up Studies; D006400:Hematocrit; D006451:Hemoglobin, Sickle / Q000378:metabolism; D006801:Humans; D000860:Hypoxia / Q000209:etiology* / Q000503:physiopathology; D015994:Incidence; D008297:Male; D010092:Oximetry; D010100:Oxygen / Q000032:analysis; D011237:Predictive Value of Tests; D011446:Prospective Studies; D012307:Risk Factors; D013577:Syndrome
D015415:Biomarkers; D006451:Hemoglobin, Sickle; D010100:Oxygen