Pyridyl thioureas as switchable anion receptors.
The binding selectivity of simple pyridyl thioureas in acetonitrile can be completely switched by protonation; hence the neutral thiourea binds acetate, but not chloride or bromide, whereas the protonated thiourea binds strongly to chloride or bromide, but is deprotonated by acetate.
Rashdan
Suad
S
School of Chemistry, University of Southampton, Southampton, UKSO17 1BJ.
Light
Mark E
ME
Kilburn
Jeremy D
JD
D000085:Acetates / Q000737:chemistry; D000838:Anions / Q000138:chemical synthesis / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D008958:Models, Molecular; D015394:Molecular Structure; D011522:Protons; D011725:Pyridines / Q000737:chemistry*; D012680:Sensitivity and Specificity; D013237:Stereoisomerism; D013890:Thiourea / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000737:chemistry*
D000085:Acetates; D000838:Anions; D011522:Protons; D011725:Pyridines; D013890:Thiourea