Influence of epicardial adipose tissue and adipocytokine levels on cardiac abnormalities in visceral obesity.
Adipocytokine levels and visceral adipose tissue (VAT) seem to be associated with some cardiac abnormalities and a role of visceral fat in predisposing to cardiac dysfunction, possibly through a low-grade state of inflammation, has been demonstrated. In this study we firstly show that elevated levels of both monocyte chemoattractant protein 1 (MCP-1) and soluble IL-6 receptor/interleukin-6 (sIL-6R/IL-6) complex are closely correlated with epicardial fat thickness.
Malavazos
Alexis E
AE
Ermetici
Federica
F
Coman
Calin
C
Corsi
Massimiliano M
MM
Morricone
Lelio
L
Ambrosi
Bruno
B
D000273:Adipose Tissue / Q000000981:diagnostic imaging*; D000328:Adult; D016022:Case-Control Studies; D018932:Chemokine CCL2 / Q000097:blood*; D005260:Female; D006346:Heart Septum / Q000000981:diagnostic imaging; D006352:Heart Ventricles / Q000000981:diagnostic imaging; D006801:Humans; D015850:Interleukin-6 / Q000097:blood*; D009765:Obesity / Q000150:complications*; D010496:Pericardium / Q000000981:diagnostic imaging*; D019947:Receptors, Interleukin-6 / Q000097:blood*; D012044:Regression Analysis; D014463:Ultrasonography
D018932:Chemokine CCL2; D015850:Interleukin-6; D019947:Receptors, Interleukin-6