title: Respiratory retraining therapy and management of laryngopharyngeal reflux in the treatment of patients with cough and paradoxical vocal fold movement disorder.
abstract: OBJECTIVE
  We describe the outcome of patients with cough and paradoxical vocal fold movement disorder (PVFMD) treated with respiratory retraining therapy and management of laryngopharyngeal reflux (LPR).
  
  
  METHODS
  Twenty patients with the complaint of cough were given a diagnosis of PVFMD and treated with proton pump inhibitors for a minimum of 6 months followed by 3 to 5 sessions of respiratory retraining therapy. Pulmonary function testing (PFT) and subjective rating of cough and reflux (reflux symptom index; RSI) were performed. Also, PFT and rating of cough were performed on a group of 10 healthy volunteers with no complaint of cough.
  
  
  RESULTS
  The study group comprised 13 women and 7 men. The baseline cough rating and ratio of forced inspiratory volume at 0.5 second to forced inspiratory vital capacity (FIV0.5/FIVC) on PFT were significantly worse in the treatment group than in the control group. After therapy, 20 patients (100%) experienced improvement in cough, 19 patients (95%) experienced improvement on PFT, and 17 patients (85%) experienced improvement in the RSI score. The differences were statistically significant.
  
  
  CONCLUSIONS
  Respiratory retraining therapy combined with management of LPR is an effective treatment for patients with cough and PVFMD when a single-modality treatment is not sufficient.
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, New York Presbyterian Hospital and Columbia University College of Physicians and Surgeons, New York, New York, USA.
authors.forename: Thomas
authors.initials: T
authors.lastname: Murry
authors.forename: Abtin
authors.initials: A
authors.lastname: Tabaee
authors.forename: Vicki
authors.initials: V
authors.lastname: Owczarzak
authors.forename: Jonathan E
authors.initials: JE
authors.lastname: Aviv
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001945:Breathing Exercises; D002908:Chronic Disease; D003371:Cough / Q000209:etiology; D005260:Female; D006801:Humans; D007818:Laryngeal Diseases / Q000150:complications / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D010608:Pharyngeal Diseases / Q000150:complications / Q000628:therapy*; D011446:Prospective Studies; D054328:Proton Pump Inhibitors; D013070:Speech Therapy / Q000379:methods; D016896:Treatment Outcome; D014827:Vocal Cords / Q000503:physiopathology*
chemical_list: D054328:Proton Pump Inhibitors