title: Gamma knife radiosurgery in the treatment of choroidal neovascularization (wet-type macular degeneration).
abstract: We evaluated retrospectively our institutional experience in the treatment of macular degeneration with gamma knife radiosurgery (GKR). Treatment was delivered in a single shot of 12 Gy. Seven patients were treated between March of 1999 and May of 2000. The median duration of follow-up was 2.2 years. The majority of patients maintained stable visual acuity after treatment. Our series indicates that GKR may be useful as a salvage treatment for patients who have failed or are ineligible for other treatments for their macular degeneration. Further studies are needed to better define the role of GKR in the treatment of macular degeneration.
authors.affiliation: Department of Radiation Oncology, Indiana University Medical Center, Indianapolis, Ind., USA.
authors.forename: Mark A
authors.initials: MA
authors.lastname: Henderson
authors.forename: Shailaja
authors.initials: S
authors.lastname: Valluri
authors.forename: Simon S
authors.initials: SS
authors.lastname: Lo
authors.forename: Thomas C
authors.initials: TC
authors.lastname: Witt
authors.forename: Robert M
authors.initials: RM
authors.lastname: Worth
authors.forename: Ronald P
authors.initials: RP
authors.lastname: Danis
authors.forename: Robert D
authors.initials: RD
authors.lastname: Timmerman
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D020256:Choroidal Neovascularization / Q000473:pathology* / Q000601:surgery*; D005260:Female; D006801:Humans; D008297:Male; D016634:Radiosurgery / Q000379:methods*; D012189:Retrospective Studies; D016879:Salvage Therapy / Q000379:methods; D016896:Treatment Outcome