title: [Cancer incidence and mortality among persons having been exposed to ionizing waves in a school in Val-de-Marne].
abstract: The Marie Curie School of Nogent-Sur-Mame (Val-de-Marne, France) was built in 1969 on the site of a former radium extracting plant. Due to remaining radioactive waste in the subsoil, school staff and students who attended the school have been exposed to radiation. A retrospective cohort study was conducted on the 3,403 persons who had attended the school regularly until it closed down in 1998. The national health insurance register was used to trace people. Incidence of cancers, leukaemia and mortality were analysed. In the population of the pupils a significant excess risk for leukaemia was observed (Standardized Incidence Ratio = 4.6 IC 95% [1.66 - 9.89]). These results are not conclusive because of the high proportion of those who could not be traced and were lost to any opportunity for follow-up (42%), and because of preferential recruitment due to a bias generated by the query of the records being centred on searching specifically for those who were sick. The difficulties met by the authors justify that when faced with similar problems in the future, greater attention should be paid to the feasibility study before any involvement or action.
authors.affiliation: Département santé-environnement, Institut de veille sanitaire, 14, rue du Val-d'Osne, 94415 Saint-Maurice, France. p.germonneau@invs.sante.fr
authors.forename: P
authors.initials: P
authors.lastname: Germonneau
authors.forename: C
authors.initials: C
authors.lastname: Castor
mesh_terms: D000328:Adult; D002274:Carcinogens, Environmental; D015331:Cohort Studies; D004781:Environmental Exposure; D005240:Feasibility Studies; D005260:Female; D005602:France; D006801:Humans; D015994:Incidence; D007953:Leukemia, Radiation-Induced / Q000453:epidemiology* / Q000401:mortality; D008228:Lymphoma, Non-Hodgkin / Q000453:epidemiology* / Q000401:mortality; D008297:Male; D009381:Neoplasms, Radiation-Induced / Q000453:epidemiology* / Q000401:mortality; D011839:Radiation, Ionizing; D011886:Radon; D012189:Retrospective Studies; D018570:Risk Assessment; D012307:Risk Factors
chemical_list: D002274:Carcinogens, Environmental; D011886:Radon