title: Enantiodifferentiation of N-benzyloxycarbonylaminophosphonic and phosphinic acids and their esters using cyclodextrins by means of capillary electrophoresis.
abstract: Capillary electrophoresis was successfully applied for separation of the enantiomers of N-benzyloxycarbonyl-alpha-aminophosphonic and alpha-aminophosphinic acids as well as their ethyl and phenyl monoesters with the use of a range of commercially available cyclodextrins (alpha, beta and hydroxypropyl-gamma-cyclodextrins) as chiral selectors. The dependence of effectiveness of separation on type and concentration of these chiral selectors as well as on pH of background electrolyte was examined in some detail.
authors.affiliation: Department of Bioorganic Chemistry, Faculty of Chemistry, Wrocław University of Technology, Wybrzeze Wyspiańskiego 27, 50-370 Wrocław, Poland.
authors.forename: Ewa
authors.initials: E
authors.lastname: Rudzińska
authors.forename: Anna
authors.initials: A
authors.lastname: Poliwoda
authors.forename: Łukasz
authors.initials: Ł
authors.lastname: Berlicki
authors.forename: Artur
authors.initials: A
authors.lastname: Mucha
authors.forename: Paweł
authors.initials: P
authors.lastname: Dzygiel
authors.forename: Piotr P
authors.initials: PP
authors.lastname: Wieczorek
authors.forename: Paweł
authors.initials: P
authors.lastname: Kafarski
mesh_terms: D003505:Cyclodextrins / Q000737:chemistry*; D019075:Electrophoresis, Capillary / Q000379:methods*; D004952:Esters; D006863:Hydrogen-Ion Concentration; D015394:Molecular Structure; D063065:Organophosphonates / Q000737:chemistry*; D010721:Phosphinic Acids / Q000737:chemistry*; D015203:Reproducibility of Results; D013237:Stereoisomerism
chemical_list: D003505:Cyclodextrins; D004952:Esters; D063065:Organophosphonates; D010721:Phosphinic Acids