[Human herpesvirus 6 encephalitis after bone marrow transplantation].
Human herpesvirus 6 (HHV-6) encephalitis may induce neurological sequelae and death; the diagnosis is difficult because of an initially poor symptomatology and of the absence of specific biochemical, electric and radiological signs. We report on a 7-year-old boy with relapsed acute lymphoblastic leukaemia, who developed HHV-6 encephalitis after bone marrow transplantation; the patient recovered after treatment with ganciclovir.
Pop-Jora
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D
Département d'Immunohématologie Pédiatrique et de Transplantation de Moelle Osseuse, Hôpital Debrousse, 69322 Lyon cedex 05, France. domnicapop@gmail.com
Berhoune
C
C
Najioullah
F
F
Girard
S
S
Mialou
V
V
Bleyzac
N
N
Galambrun
C
C
Bertrand
Y
Y
D000998:Antiviral Agents / Q000008:administration & dosage / Q000627:therapeutic use; D016026:Bone Marrow Transplantation / Q000009:adverse effects*; D002648:Child; D018792:Encephalitis, Viral / Q000188:drug therapy / Q000209:etiology / Q000821:virology; D005500:Follow-Up Studies; D015774:Ganciclovir / Q000008:administration & dosage / Q000627:therapeutic use; D006086:Graft vs Host Disease / Q000150:complications; D015654:Herpesvirus 6, Human; D006801:Humans; D008297:Male; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000628:therapy; D012008:Recurrence; D019349:Roseolovirus Infections / Q000188:drug therapy / Q000821:virology; D013997:Time Factors; D016896:Treatment Outcome
D000998:Antiviral Agents; D015774:Ganciclovir