title: Mosaic staphylococcal cassette chromosome mec containing two recombinase loci and a new mec complex, B2.
abstract: A novel staphylococcal cassette chromosome (SCC) mec from a clinical methicillin-resistant Staphylococcus aureus isolate (ST100/CC5) had a mosaic structure, composed of SCC DNA from several different backgrounds. It harbored two complete ccr loci and a new variant of mec complex B, with DeltamecR1 interrupted by the aminoglycoside resistance transposon Tn4001.
authors.affiliation: Institute of Medical Microbiology, University of Zurich, 8006 Zurich, Switzerland.
authors.forename: R
authors.initials: R
authors.lastname: Heusser
authors.forename: M
authors.initials: M
authors.lastname: Ender
authors.forename: B
authors.initials: B
authors.lastname: Berger-Bächi
authors.forename: N
authors.initials: N
authors.lastname: McCallum
mesh_terms: D000617:Aminoglycosides / Q000494:pharmacology; D002874:Chromosome Mapping; D002876:Chromosomes, Bacterial / Q000235:genetics; D004251:DNA Transposable Elements / Q000235:genetics*; D005798:Genes, Bacterial; D007527:Isoenzymes / Q000235:genetics; D016106:Methicillin Resistance / Q000235:genetics; D008826:Microbial Sensitivity Tests; D008969:Molecular Sequence Data; D045522:Recombinases / Q000235:genetics*; D013210:Staphylococcus / Q000187:drug effects / Q000235:genetics*
chemical_list: D000617:Aminoglycosides; D004251:DNA Transposable Elements; D007527:Isoenzymes; D045522:Recombinases