A tale in molecular recognition: the hammerhead ribozyme.
A new crystal structure of the hammerhead ribozyme demonstrates the influence of peripheral tertiary contacts on the local conformations around the active site. This structure resolves many conflicting results obtained on reduced systems.
Westhof
Eric
E
Architecture et Réactivité de l'ARN, Institut de Biologie Moléculaire et Cellulaire du CNRS, Strasbourg, France. E.Westhof@ibmc.u-strasbg.fr
D000818:Animals; D001483:Base Sequence; D002384:Catalysis; D008969:Molecular Sequence Data; D009690:Nucleic Acid Conformation; D016337:RNA, Catalytic / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D012550:Schistosoma mansoni / Q000737:chemistry
D016337:RNA, Catalytic; C427204:hammerhead ribozyme