Kaposi sarcoma in a patient with giant cell arteritis.
Kaposi sarcoma usually occurs in immunosuppressed patients. A classic type has been reported in elderly men of Jewish and Mediterranean origin. We report a case of an elderly woman with giant cell arteritis (GCA) who developed Kaposi sarcoma while on a double blind trial for GCA with an anti-tumor-necrosis-factor medication. Our patient had none of the risk factors for Kaposi sarcoma, and when she was withdrawn from the study it was found that she was receiving only placebo along with the moderate, tapering doses of corticosteroids.
Kuttikat
Anoop
A
Departments of Rheumatology and Histopathology, Haroldwood Hospital, Romford, Essex.
Joshi
Abhay
A
Saeed
Ibtisam
I
Chakravarty
Kuntal
K
D000305:Adrenal Cortex Hormones / Q000009:adverse effects / Q000627:therapeutic use; D000368:Aged; D004311:Double-Blind Method; D005260:Female; D013700:Giant Cell Arteritis / Q000150:complications / Q000188:drug therapy*; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects; D010919:Placebos; D011239:Prednisolone / Q000009:adverse effects / Q000627:therapeutic use; D016032:Randomized Controlled Trials as Topic; D012075:Remission, Spontaneous; D012514:Sarcoma, Kaposi / Q000097:blood / Q000209:etiology*; D012878:Skin Neoplasms / Q000097:blood / Q000209:etiology*; D014786:Vision Disorders / Q000209:etiology
D000305:Adrenal Cortex Hormones; D007166:Immunosuppressive Agents; D010919:Placebos; D011239:Prednisolone