title: Cleft palate in Kabuki syndrome: a report of six cases.
abstract: Kabuki syndrome is a syndrome of rare congenital anomalies that was named after its characteristic appearance, a face resembling that of an actor in a Kabuki play. Although cleft palate is a feature that is sometimes observed in patients with Kabuki syndrome, there are few clinical reports of cleft palate associated with Kabuki syndrome. This report presents six cases of Kabuki syndrome with cleft palate and reviews their clinical features. Our results suggest that (1) patients with cleft palate in Kabuki syndrome tend to fail in acquiring normal velopharyngeal function and (2) submucous cleft palate might be more common in patients with Kabuki syndrome than previously was reported.
authors.affiliation: Department of Plastic and Reconstructive Surgery, Shizuoka Cancer Center, 1007 Shimonagakubo, Nagai-zumi, Shizuoka 411-8777, Japan. tiida-tky@umin.ac.jp
authors.forename: Takuya
authors.initials: T
authors.lastname: Iida
authors.forename: Susam
authors.initials: S
authors.lastname: Park
authors.forename: Kogo
authors.initials: K
authors.lastname: Kato
authors.forename: Ichiko
authors.initials: I
authors.lastname: Kitano
mesh_terms: D000015:Abnormalities, Multiple; D001184:Articulation Disorders / Q000628:therapy; D002972:Cleft Palate / Q000473:pathology* / Q000601:surgery; D019465:Craniofacial Abnormalities / Q000473:pathology*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D010159:Palate / Q000601:surgery; D010614:Pharynx / Q000601:surgery; D013524:Surgical Flaps; D013577:Syndrome; D014681:Velopharyngeal Insufficiency / Q000628:therapy