Torsades de pointes following concurrent amiodarone and levofloxacin therapy.
A case of torsades de pointes is reported following administration of amiodarone concurrent with the fluoroquinolone levofloxacin. Prolongation of the QTc interval has occurred with the fluoroquinolone class of antibiotics. The incidence of torsades has been considered rare with amiodarone. Caution is warranted when these two agents are administered concurrently.
Maxa
Jan Louise
JL
Department of Pharmacy Services, Baylor University Medical Center, Dallas, Texas, USA. janma@BaylorHealth.edu
Hebeler
Robert Frederick
RF
Adeeko
M Alade
MA