Leukemoid reaction in pancreatic cancer: a case report and review of the literature.
BACKGROUND
The presentation of pancreatic cancer with a leukemoid reaction is rare with no prior reports in the English language literature.


METHODS
We report a case of advanced pancreatic cancer presenting with leukemoid reaction. Granulocyte colony-stimulating factor and granulocyte-macrophage colony-stimulating factor levels were normal while interleukin-6 was elevated. The patient had no evidence of infection. The leukemoid reaction correlated with tumor response.


CONCLUSIONS
This is the first case report in the English literature of a leukemoid paraneoplastic syndrome in a patient with pancreatic cancer. A clear correlation between tumor response, serum carbohydrate antigen 19-9 levels and leukemoid reaction is documented.
Qureshi
Khusroo M
KM
Department of Medicine, Roswell Park Cancer Institute, Buffalo, NY 14263, USA.
Raman
Arun K
AK
Tan
Dongfeng
D
Fakih
Marwan G
MG
D000230:Adenocarcinoma / Q000150:complications* / Q000175:diagnosis* / Q000000981:diagnostic imaging; D006801:Humans; D007955:Leukemoid Reaction / Q000150:complications* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009362:Neoplasm Metastasis / Q000175:diagnosis / Q000000981:diagnostic imaging; D010190:Pancreatic Neoplasms / Q000150:complications* / Q000175:diagnosis* / Q000000981:diagnostic imaging; D011859:Radiography