Simultaneous solid-phase synthesis of quinoxalinone and benzimidazole scaffold libraries.
This article describes a method for simultaneous solid-phase synthesis of a quinoxalinone and benzimidazole scaffold library that consists of 240 members. The library was generated by using the solid-phase "split-and-pool" approach and the IRORI sorting system.
Kou
Bin-Bin
BB
Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, 1 Xian Nong Tan Street, Beijing 100050, PR China.
Zhang
Fa
F
Yang
Tian-Ming
TM
Liu
Gang
G
D001562:Benzimidazoles / Q000138:chemical synthesis* / Q000737:chemistry; D020650:Combinatorial Chemistry Techniques / Q000379:methods*; D015394:Molecular Structure; D011810:Quinoxalines / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
D001562:Benzimidazoles; D011810:Quinoxalines