Living kidney donors developing end-stage renal disease.
The incidence of end-stage kidney failure (ESRF) was analyzed among the cohort of 1112 living kidney donors who underwent nephrectomy from 1965 through 2005. It was found that at least six persons had developed ESRF at 14 to 27 years (median = 20 years), following donation. Five of six were men. Five were parents and one, a sibling. The diagnoses were nephrosclerosis (n = 4), postrenal failure (n = 1), and renal carcinoma (n = 1). One donor, aged 45 years, underwent kidney transplantation.
Fehrman-Ekholm
I
I
Department of Transplantation and Liver Surgery, Sahlgrenska University Hospital, Göteborg, Sweden. ingela.fehrman-ekholm@vgregion.se
Nordén
G
G
Lennerling
A
A
Rizell
M
M
Herlitz
H
H
Nielsen
F-D
FD
Storkamp
O
O
Deurell
S-I
SI
Olausson
M
M
D015331:Cohort Studies; D005220:Fathers; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007676:Kidney Failure, Chronic / Q000453:epidemiology* / Q000209:etiology; D007680:Kidney Neoplasms / Q000453:epidemiology; D019520:Living Donors; D008297:Male; D009035:Mothers; D009392:Nephrectomy / Q000009:adverse effects*; D012189:Retrospective Studies; D013997:Time Factors; D020858:Tissue and Organ Harvesting