Radiation therapy for incompletely excised grade II canine mast cell tumors.
Forty-five dogs with incompletely excised grade II mast cell tumors were treated with radiation using a cobalt 60 teletherapy unit (15 fractions of 3.2 Gy for a total of 48 Gy). Twenty-four of the dogs underwent prophylactic regional lymph node irradiation. Three (6.7%) dogs had tumor recurrence, two (4.4%) dogs developed metastasis, and 14 (31%) dogs developed a second cutaneous mast cell tumor. No difference in overall survival rate was observed between the dogs receiving and not receiving prophylactic irradiation of the regional lymph node.
Poirier
Valerie Jasmine
VJ
Department of Diagnostic Imaging and Radiation Oncology, Vetsuisse Faculty, University of Zurich, Wintherthurerstrasse 260, Zurich, 8057 Switzerland.
Adams
William M
WM
Forrest
Lisa J
LJ
Green
Eric M
EM
Dubielzig
Richard R
RR
Vail
David M
DM
D000818:Animals; D003036:Cobalt Isotopes / Q000627:therapeutic use* / Q000633:toxicity; D004283:Dog Diseases / Q000401:mortality / Q000532:radiotherapy*; D004285:Dogs; D005260:Female; D053208:Kaplan-Meier Estimate; D008198:Lymph Nodes / Q000528:radiation effects; D008207:Lymphatic Metastasis / Q000517:prevention & control; D008297:Male; D034801:Mastocytoma / Q000401:mortality / Q000532:radiotherapy / Q000662:veterinary*; D009364:Neoplasm Recurrence, Local / Q000517:prevention & control / Q000662:veterinary; D011867:Radioisotope Teletherapy / Q000662:veterinary*; D012189:Retrospective Studies; D012720:Severity of Illness Index; D013997:Time Factors; D016896:Treatment Outcome
D003036:Cobalt Isotopes