Human immunodeficiency viruses: SIV infection in wild gorillas.
Chimpanzees (Pan troglodytes troglodytes) from west central Africa are recognized as the reservoir of simian immunodeficiency viruses (SIVcpzPtt) that have crossed at least twice to humans: this resulted in the AIDS pandemic (from human immunodeficiency virus HIV-1 group M) in one instance and infection of just a few individuals in Cameroon (by HIV-1 group N) in another. A third HIV-1 lineage (group O) from west central Africa also falls within the SIVcpzPtt radiation, but the primate reservoir of this virus has not been identified. Here we report the discovery of HIV-1 group O-like viruses in wild gorillas.
Van Heuverswyn
Fran
F
UMR145, Institut de Recherche pour le Développement and Department of International Health, University of Montpellier 1, 34394 Montpellier Cedex 5, France.
Li
Yingying
Y
Neel
Cecile
C
Bailes
Elizabeth
E
Keele
Brandon F
BF
Liu
Weimin
W
Loul
Severin
S
Butel
Christelle
C
Liegeois
Florian
F
Bienvenue
Yanga
Y
Ngolle
Eitel Mpoudi
EM
Sharp
Paul M
PM
Shaw
George M
GM
Delaporte
Eric
E
Hahn
Beatrice H
BH
Peeters
Martine
M
D000818:Animals; D000835:Animals, Wild / Q000821:virology*; D002163:Cameroon / Q000453:epidemiology; D005243:Feces / Q000821:virology; D006071:Gorilla gorilla / Q000145:classification / Q000821:virology*; D006801:Humans; D002679:Pan troglodytes / Q000821:virology; D016097:Simian Acquired Immunodeficiency Syndrome / Q000453:epidemiology / Q000635:transmission / Q000821:virology*; D015302:Simian Immunodeficiency Virus / Q000145:classification / Q000302:isolation & purification*; D015047:Zoonoses / Q000635:transmission / Q000821:virology