Primary diffuse large B-cell lymphoma of the skin.
B-cell lymphomas of the skin represent a wide spectrum of disorders. We present the microscopic and immunohistochemical features of a primary cutaneous B-cell lymphoma and classify it either as a diffuse large B-cell lymphoma or an indolent follicle-center-cell lymphoma according to the updated REAL/WHO system and the EORTC classification respectively. The former system is widely recommended; nevertheless, the EORTC system is also worth considering when planning management, because most data on long-term outcomes are based on it and it is considered to offer remarkable prognostic information.
Lazaris
Andreas C
AC
Department of Pathology, Medical School, National and Kapodistrian University of Athens, Greece. alazaris@med.uoa.gr
Nonni
Aphrodite
A
Pathiaki
Irene
I
Patsouris
Efstratios
E
D018951:Antigens, CD20 / Q000032:analysis; D000951:Antigens, Neoplasm / Q000032:analysis; D006801:Humans; D017730:Ki-1 Antigen / Q000032:analysis; D016393:Lymphoma, B-Cell / Q000737:chemistry / Q000145:classification / Q000473:pathology*; D016403:Lymphoma, Large B-Cell, Diffuse / Q000737:chemistry / Q000145:classification / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D012878:Skin Neoplasms / Q000737:chemistry / Q000473:pathology*
D018951:Antigens, CD20; D000951:Antigens, Neoplasm; D017730:Ki-1 Antigen