title: Skin test reactivity to aeroallergens in Jamaicans: relationship to asthma.
abstract: BACKGROUND
  Asthma causes significant morbidity and mortality in the developing world. It is thus important to identify modifiable risk factors.
  
  
  OBJECTIVE
  To undertake a cross-sectional study to determine the prevalence of skin test reactivity to aeroallergens in Jamaican children and adults and the relationship of the diagnosis of asthma to the pattern of skin test positivity.
  
  
  METHODS
  One hundred and sixty subjects without the sickle cell gene (genotype AA), eighty adults and eighty children, were recruited. Skin testing to seven aeroallergens was undertaken (atopy being diagnosed if there were at least one positive reaction). Asthma status was determined by a questionnaire and/or medical records.
  
  
  RESULTS
  Twenty-seven (34%) of the children and forty-one (51%) of the adults were skin test positive to at least one aeroallergen. The most common positive responses in both age groups were to Dermatophagoides farinae, Dermatophagoides pteronyssinus and cockroach mix-(German and American). All adult asthmatics with current symptoms reacted to cockroach allergen.
  
  
  CONCLUSIONS
  Appropriate steps to reduce cockroaches and cockroach sensitization might positively impact on asthma morbidity in Jamaica.
authors.affiliation: Sickle Cell Unit, Tropical Medicine Research Institute, The University of the West Indies, Kingston 7, Jamaica, West Indies. jennifer.knightmadden@uwimona.edu.jm
authors.forename: J
authors.initials: J
authors.lastname: Knight-Madden
authors.forename: T E
authors.initials: TE
authors.lastname: Forrester
authors.forename: I R
authors.initials: IR
authors.lastname: Hambleton
authors.forename: N
authors.initials: N
authors.lastname: Lewis
authors.forename: A
authors.initials: A
authors.lastname: Greenough
mesh_terms: D000293:Adolescent; D000328:Adult; D000485:Allergens; D000818:Animals; D039741:Antigens, Dermatophagoides; D001249:Asthma / Q000175:diagnosis / Q000276:immunology* / Q000503:physiopathology; D002648:Child; D003058:Cockroaches; D003430:Cross-Sectional Studies; D040001:Dermatophagoides farinae; D040002:Dermatophagoides pteronyssinus; D004391:Dust; D005260:Female; D006801:Humans; D006969:Hypersensitivity, Immediate / Q000276:immunology* / Q000503:physiopathology; D007563:Jamaica; D008297:Male; D008925:Mites; D015995:Prevalence; D012220:Rhinitis; D012882:Skin Tests; D011795:Surveys and Questionnaires
chemical_list: D000485:Allergens; D039741:Antigens, Dermatophagoides; D004391:Dust