title: Possible impact of autologous blood towards elective open and laparoscopic surgery for colorectal carcinoma.
abstract: OBJECTIVE
  An alternative approach to the allogeneic transfusion is patient's blood collection before the operation, using or not using the human recombinant erythropoietin. The aim of this study is to evaluate the percentage of people undergoing an elective operation for colorectal carcinoma who could avoid allogeneic blood due to blood predonation.
  
  
  METHODS
  From January 1999 to April 2002, 249 patients (140 males and 109 females) underwent an operation for colorectal cancer. The most important parameter, used to estimate which patients are candidates for autologous blood predonation, is the before-treatment hemoglobin level. The other parameters we considered are the age of the patient, the absence of uncontrolled hypertension or clinically significant pathologies (except colorectal cancer), and the iron shortage.
  
  
  METHODS
  Retrospective cohort study.
  
  
  RESULTS
  36.5% of the patients satisfied every criterion to begin autologous predonation without using the human recombinant erythropoietin; instead, 23.7% of patients needed the administration of the human recombinant erythropoietin and additional iron. The valuation of the transfusional prospects, based on sex and cancer location is very interesting.
  
  
  CONCLUSIONS
  Autologous blood predeposit in preoperational time turns out to be a method of increasing importance, thanks to the human recombinant erythropoietin.
authors.affiliation: Second Department of Surgery, University of Turin, Italy.
authors.forename: Valentino
authors.initials: V
authors.lastname: Festa
authors.forename: Paolo
authors.initials: P
authors.lastname: Bosio
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Giraudo
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Cavuoti
authors.forename: Stefania
authors.initials: S
authors.lastname: Soncini
authors.forename: Mario
authors.initials: M
authors.lastname: Morino
mesh_terms: D000230:Adenocarcinoma / Q000601:surgery*; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001804:Blood Transfusion, Autologous; D003082:Colectomy; D015179:Colorectal Neoplasms / Q000601:surgery*; D017558:Elective Surgical Procedures; D004921:Erythropoietin / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011994:Recombinant Proteins
chemical_list: D011994:Recombinant Proteins; D004921:Erythropoietin