title: Does obstructive sleep apnea affect aerobic fitness?
abstract: OBJECTIVE
  We sought to determine whether patients with obstructive sleep apnea (OSA) had an objective change in aerobic fitness during cycle ergometry compared to a normal population. The most accurate test of aerobic fitness is measurement of maximum oxygen consumption (VO2max) with cycle ergometry.
  
  
  METHODS
  We performed a retrospective cohort analysis (247 patients with OSA) of VO2max from annual cycle ergometry tests compared to a large control group (normative data from 1.4 million US Air Force tests) in a tertiary care setting.
  
  
  RESULTS
  Overall, individuals with OSA had increased VO2max when compared to the normalized US Air Force data (p < .001). Patients with an apnea-hypopnea index of greater than 20 demonstrated a decreased VO2max as compared to normalized values (p < .001). No differences in VO2max were observed after either medical or surgical therapy for OSA.
  
  
  CONCLUSIONS
  Overall, in a US Air Force population, OSA does not predict a decrease in aerobic fitness as measured by cycle ergometry. However, patients with an apnea-hypopnea index of greater than 20 have a statistically significant decrease in aerobic fitness compared to the normal population. This study demonstrates the effects of OSA on aerobic fitness. Further correlation of fitness testing results with OSA severity and treatment is needed.
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, Wilford Hall United States Air Force Medical Center, San Antonio, Texas, USA.
authors.forename: Louis Q
authors.initials: LQ
authors.lastname: Guillermo
authors.forename: Thomas J
authors.initials: TJ
authors.lastname: Gal
authors.forename: Eric A
authors.initials: EA
authors.lastname: Mair
mesh_terms: D000293:Adolescent; D000328:Adult; D015331:Cohort Studies; D045422:Continuous Positive Airway Pressure; D005080:Exercise Test; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D008889:Military Personnel; D010101:Oxygen Consumption / Q000502:physiology*; D010809:Physical Fitness / Q000502:physiology*; D012189:Retrospective Studies; D020181:Sleep Apnea, Obstructive / Q000503:physiopathology* / Q000628:therapy; D014481:United States