High incidence of chromosomal abnormalities in oocyte donors.
Oocyte donors are chosen among phenotypically normal and fertile women who are not expected to carry any chromosomal abnormality. A high incidence of balanced structural chromosomal rearrangements has been found within oocyte donors. This result raises the question of a possible bias in their recruitment with respect to their familial background and/or personal reproductive history.
Ravel
Célia
C
CECOS Paris Tenon, Hôpital Tenon, Paris, France.
Letur
Hélène
H
Le Lannou
Dominique
D
Barthélémy
Claire
C
Bresson
Jean Luc
JL
Siffroi
Jean Pierre
JP
D000328:Adult; D002869:Chromosome Aberrations / Q000706:statistics & numerical data*; D025063:Chromosome Disorders / Q000453:epidemiology* / Q000235:genetics*; D005260:Female; D005602:France / Q000453:epidemiology; D006801:Humans; D015994:Incidence; D018587:Oocyte Donation / Q000706:statistics & numerical data*; D012189:Retrospective Studies; D014019:Tissue Donors / Q000706:statistics & numerical data*