title: Substrate-directed stereoselectivity in vicinal diamine-catalyzed synthesis of warfarin.
abstract: [Structure: see text] A new mechanism involving a diimine intermediate is proposed for vicinal diamine-catalyzed synthesis of warfarin. Decreasing the NCCN dihedral angle by varying the diamine results in an increase in the enantioselectivity of warfarin synthesis.
authors.affiliation: Department of Chemistry, University of Toronto, 80 St. Geroge Street, Toronto, ON, M5S 3H6 Canada.
authors.forename: Hyunwoo
authors.initials: H
authors.lastname: Kim
authors.forename: Cindy
authors.initials: C
authors.lastname: Yen
authors.forename: Philippa
authors.initials: P
authors.lastname: Preston
authors.forename: Jik
authors.initials: J
authors.lastname: Chin