title: Usefulness of scintimammography as an adjunct to mammography and ultrasound in the diagnosis of breast diseases.
abstract: This study was undertaken to evaluate the diagnostic efficacy of 99mtechnetium methoxyisobutylisonitrile scintimammography (SM) and combined use of mammography and ultrasound in the detection of the breast lesions in the symptomatic breast. Histopathological findings were the gold standard. Eighty patients with symptomatic breasts underwent mammography and/or ultrasound breast followed by SM. In 25 patients there were 27 lesions that were malignant and 55 patients had 65 lesions that were benign. Sensitivity, specificity, positive predictive value, negative predictive value and accuracy of SM were found to be 92, 72, 58, 96 and 78%, respectively, as compared with the combined use of mammography and ultrasound, which showed these parameters to be 89, 94, 86, 95 and 92%, respectively. In this study, SM showed slightly better sensitivity than combined mammography and ultrasound, whereas the specificity was clearly shown as higher in the latter.
authors.affiliation: Department of Radiology, Faculty of Medicine, Kuwait University, and Mubarak Al-Kabeer Hospital, Kuwait. renu@hsc.edu.kw
authors.forename: R
authors.initials: R
authors.lastname: Gupta
authors.forename: D
authors.initials: D
authors.lastname: Collier
authors.forename: S
authors.initials: S
authors.lastname: Abdeen
authors.forename: L
authors.initials: L
authors.lastname: Roberts
authors.forename: A Y T
authors.initials: AY
authors.lastname: Hussein
authors.forename: I
authors.initials: I
authors.lastname: Al-Bader
authors.forename: G M
authors.initials: GM
authors.lastname: Syed
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001941:Breast Diseases / Q000000981:diagnostic imaging*; D016009:Chi-Square Distribution; D006801:Humans; D008327:Mammography; D008875:Middle Aged; D011237:Predictive Value of Tests; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals; D012680:Sensitivity and Specificity; D017256:Technetium Tc 99m Sestamibi; D016217:Ultrasonography, Mammary
chemical_list: D019275:Radiopharmaceuticals; D017256:Technetium Tc 99m Sestamibi