Upregulation of aspartoacylase seen in diabetes is due to advanced glycation end-products.
Surendran
Sankar
S
D000581:Amidohydrolases / Q000096:biosynthesis*; D003929:Diabetic Neuropathies / Q000201:enzymology / Q000378:metabolism*; D005786:Gene Expression Regulation; D005947:Glucose / Q000378:metabolism; D017127:Glycation End Products, Advanced / Q000378:metabolism*; D006801:Humans; D008659:Metabolic Diseases; D008954:Models, Biological; D008962:Models, Theoretical; D009474:Neurons / Q000378:metabolism; D018384:Oxidative Stress; D015854:Up-Regulation
D017127:Glycation End Products, Advanced; D000581:Amidohydrolases; C019751:aspartoacylase; D005947:Glucose