title: [Quorum-sensing system in Candida albicans].
abstract: The bacterial behavior system controlled by the cell density is described as quorum-sensing. The system is triggered via autoinducers. Various kinds of autoinducers have been identified from different bacteria. Quorum-sensing signals via autoinducers are involved in regulation of important virulences such as exotoxin, protease, and pigment production. Therefore, this system in pathogenic bacteria has a critical role in the regulation of bacterial pathogenicity. In the pathogenic fungus Candida albicans, an extracellular quorum-sensing molecule that regulates hyphal formation by this organism has been identified in recent years. Candida albicans has been shown to form biofilm on many medical devices, therefore quorum-sensing in this organism has been especially focused on from the aspect of biofilm formation.
authors.affiliation: Section of Infection Biology, Fukuoka Dental College, Japan.
authors.forename: Tamaki
authors.initials: T
authors.lastname: Cho
authors.forename: Mika
authors.initials: M
authors.lastname: Toyoda
authors.forename: Hironobu
authors.initials: H
authors.lastname: Nakayama
authors.forename: Hiroji
authors.initials: H
authors.lastname: Chibana
authors.forename: Hidenori
authors.initials: H
authors.lastname: Kaminishi
mesh_terms: D018441:Biofilms / Q000254:growth & development; D002176:Candida albicans / Q000502:physiology*; D053038:Quorum Sensing / Q000502:physiology*