title: [Predictive value and sensibility of hospital discharge system (PMSI) compared to cancer registries for thyroïd cancer (1999-2000)].
abstract: BACKGROUND
  Cancer registries have a complete recording of new cancer cases occurring among residents of a specific geographic area. In France, they cover only 13% of the population. For thyroid cancer, where incidence rate is highly variable according to the district conversely to mortality, national incidence estimates are not accurate. A nationwide database, such as hospital discharge system, could improve this estimate but its positive predictive value and sensibility should be evaluated.
  
  
  METHODS
  The positive predictive value and the sensitivity for thyroid cancer case ascertainment (ICD-10) of the national hospital discharge system in 1999 and 2000 were estimated using the cancer registries database of 10 French districts as gold standard. The linkage of the two databases required transmission of nominative information from the health facilities of the study. From the registries database, a logistic regression analysis was carried out to identify factors related to being missed by the hospital discharge system.
  
  
  RESULTS
  Among the 973 standardized discharge charts selected from the hospital discharge system, 866 were considered as true positive cases, and 107 as false positive. Forty five of the latter group were prevalent cases. The predictive positive value was 89% (95% confidence interval (CI): 87-91%) and did not differ according to the district (p=0,80). According to the cancer registries, 322 thyroid cancer cases diagnosed in 1999 or 2000 were missed by the hospital discharge system. Thus, the sensitivity of this latter system was 73% (70-76%) and varied significantly from 62% to 85% across districts (p<0.001) and according to the type of health facility (p<0.01).
  
  
  CONCLUSIONS
  Predictive positive value of the French hospital discharge system for ascertainment of thyroid cancer cases is high and stable across districts. Sensitivity is lower and varies significantly according to the type of health facility and across districts, which limits the interest of this database for a national estimate of thyroid cancer incidence rate.
authors.affiliation: Département des Maladies chroniques et Traumatismes, Institut de Veille Sanitaire, InVS, 12, rue du Val-d'Osne, 94415 Saint-Maurice. nicolas.carre@sante.gouv.fr
authors.forename: N
authors.initials: N
authors.lastname: Carré
authors.forename: Z
authors.initials: Z
authors.lastname: Uhry
authors.forename: M
authors.initials: M
authors.lastname: Velten
authors.forename: B
authors.initials: B
authors.lastname: Trétarre
authors.forename: C
authors.initials: C
authors.lastname: Schvartz
authors.forename: F
authors.initials: F
authors.lastname: Molinié
authors.forename: N
authors.initials: N
authors.lastname: Maarouf
authors.forename: C
authors.initials: C
authors.lastname: Langlois
authors.forename: P
authors.initials: P
authors.lastname: Grosclaude
authors.forename: M
authors.initials: M
authors.lastname: Colonna
mesh_terms: D000367:Age Factors; D000368:Aged; D000465:Algorithms; D005260:Female; D005602:France; D006801:Humans; D015994:Incidence; D016015:Logistic Models; D008297:Male; D008499:Medical Records; D008875:Middle Aged; D010351:Patient Discharge; D012042:Registries; D012680:Sensitivity and Specificity; D012737:Sex Factors; D013964:Thyroid Neoplasms / Q000453:epidemiology*