title: Poorly differentiated squamous cell carcinoma coexisting with angiofibroma and spreading as intravascular emboli in its vessels.
abstract: We report a case of a 28-year-old male who presented with epistaxis and hyponasal speech. A clinical and radiological diagnosis of nasopharyngeal angiofibroma was made. The patient underwent a modified transpalatal resection of the tumor under general anesthesia. A diagnosis of poorly differentiated carcinoma, possibly squamous, with extensive embolization in the vessels of angiofibroma was made. As the two entities have entirely different management and outcome, it is imperative to distinguish and locate the malignant component.
authors.affiliation: Department of Pathology, Maulana Azad Medical College, New Delhi, India.
authors.forename: Kajal
authors.initials: K
authors.lastname: Dhingra
authors.forename: Niti
authors.initials: N
authors.lastname: Singhal
authors.forename: Nita
authors.initials: N
authors.lastname: Khurana
mesh_terms: D000328:Adult; D018322:Angiofibroma / Q000098:blood supply / Q000473:pathology*; D002294:Carcinoma, Squamous Cell / Q000473:pathology*; D006801:Humans; D008297:Male; D009303:Nasopharyngeal Neoplasms / Q000098:blood supply / Q000473:pathology*; D009378:Neoplasms, Multiple Primary / Q000473:pathology*; D009360:Neoplastic Cells, Circulating / Q000473:pathology*