[Quorum-sensing system in Candida albicans].
The bacterial behavior system controlled by the cell density is described as quorum-sensing. The system is triggered via autoinducers. Various kinds of autoinducers have been identified from different bacteria. Quorum-sensing signals via autoinducers are involved in regulation of important virulences such as exotoxin, protease, and pigment production. Therefore, this system in pathogenic bacteria has a critical role in the regulation of bacterial pathogenicity. In the pathogenic fungus Candida albicans, an extracellular quorum-sensing molecule that regulates hyphal formation by this organism has been identified in recent years. Candida albicans has been shown to form biofilm on many medical devices, therefore quorum-sensing in this organism has been especially focused on from the aspect of biofilm formation.
Cho
Tamaki
T
Section of Infection Biology, Fukuoka Dental College, Japan.
Toyoda
Mika
M
Nakayama
Hironobu
H
Chibana
Hiroji
H
Kaminishi
Hidenori
H
D018441:Biofilms / Q000254:growth & development; D002176:Candida albicans / Q000502:physiology*; D053038:Quorum Sensing / Q000502:physiology*