title: [Necrotizing cellulitis complicating varicella in two children given nonsteroidal anti-inflammatory drugs].
abstract: We report two cases of fasciitis with necrotizing hypodermitis of the foot and arm which complicated varicella in immunocompetent children given nonsteroidal anti-inflammatory drugs. The skin barrier and immune function are weakened by the varicella zoster virus. Exposure to nonsteroidal anti-inflammatory drugs further favors necrotizing cutaneous infections caused by group A beta hemolytic streptococci. MRI can confirm the presence of superficial aponevrosis necrosis defining necrotizing fasciitis but should not retard surgical management which is always indicated for necrotizing fasciitis and sometimes for necrotizing dermo-hypodermitis.
authors.affiliation: Service de Chirurgie Infantile, Hôpital Nord, chemin des Bourrelys, 13915 Marseille Cedex 20. louis.marie-laure@neuf.fr
authors.forename: M-L
authors.initials: ML
authors.lastname: Louis
authors.forename: F
authors.initials: F
authors.lastname: Launay
authors.forename: J-M
authors.initials: JM
authors.lastname: Guillaume
authors.forename: F
authors.initials: F
authors.lastname: Sabiani
authors.forename: K
authors.initials: K
authors.lastname: Chaumoître
authors.forename: K
authors.initials: K
authors.lastname: Retornaz
authors.forename: J-M
authors.initials: JM
authors.lastname: Gennari
authors.forename: G
authors.initials: G
authors.lastname: Bollini
mesh_terms: D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects*; D002481:Cellulitis / Q000209:etiology* / Q000473:pathology*; D002644:Chickenpox / Q000150:complications* / Q000188:drug therapy*; D002675:Child, Preschool; D006801:Humans; D007223:Infant; D008297:Male; D009336:Necrosis
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal