Heterogeneous epileptogenicity and cortical function within malformations of cortical development: a case report.
The authors report a 24-year-old patient with intractable partial epilepsy and massive malformations of cortical development (MCD). Subdural EEG recordings of habitual seizures showed heterogeneous epileptogenicity, and visual evoked potential was recorded within the MCD just adjacent to the most active epileptogenic focus. Resection of the small cortical area presumably with core epileptogenicity, while sparing the cortical functional area, improved seizure outcome without any postoperative functional deficits.
Kinoshita
Masako
M
Department of Neurology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Ikeda
Akio
A
Taki
Junya
J
Usui
Keiko
K
Matsumoto
Riki
R
Mikuni
Nobuhiro
N
Takahashi
Jun B
JB
Fukuyama
Hidenao
H
Hashimoto
Nobuo
N
Takahashi
Ryosuke
R
D000328:Adult; D001931:Brain Mapping; D004566:Electrodes; D004569:Electroencephalography / Q000379:methods; D004828:Epilepsies, Partial / Q000473:pathology / Q000503:physiopathology*; D005074:Evoked Potentials, Visual / Q000502:physiology; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D014793:Visual Cortex / Q000503:physiopathology*