COMP-structure-based design and development of estrogen receptor modulators.
Rotella
David
D
Wyeth Research, CN 8000, Princeton, NJ 0854, USA. rotelld@wyeth.com
D003198:Computer Simulation; D015195:Drug Design; D015507:Drugs, Investigational / Q000737:chemistry* / Q000494:pharmacology*; D020847:Estrogen Receptor Modulators / Q000737:chemistry* / Q000494:pharmacology*; D047629:Estrogen Receptor beta / Q000819:agonists; D006801:Humans; D008297:Male; D008958:Models, Molecular; D010080:Oxazoles / Q000494:pharmacology; D011470:Prostatic Hyperplasia / Q000188:drug therapy; D011960:Receptors, Estrogen / Q000819:agonists; D020845:Selective Estrogen Receptor Modulators / Q000737:chemistry / Q000494:pharmacology; D013329:Structure-Activity Relationship
D015507:Drugs, Investigational; C478102:ERB 041; D020847:Estrogen Receptor Modulators; D047629:Estrogen Receptor beta; D010080:Oxazoles; D011960:Receptors, Estrogen; D020845:Selective Estrogen Receptor Modulators