Current rectification with poly-l-lysine-coated quartz nanopipettes.
Ion current rectification with quartz nanopipette electrodes was investigated through the control of the surface charge. The presence and absence of a positively charged poly-l-lysine (PLL) coating resulted in the rectified current with opposite polarity. The results agreed with the theories developed for current-rectifying conical nanopores, suggesting the similar underlying mechanism among asymmetric nanostructure in general. This surface condition dependence can be used as the fundamental principle of multi-purpose real-time in vivo biosensors.
Umehara
Senkei
S
Stanford Genome Technology Center, Department of Biochemistry, Stanford University School of Medicine, Stanford University, 855 California Avenue, Palo Alto, California 94304, USA.
Pourmand
Nader
N
Webb
Chris D
CD
Davis
Ronald W
RW
Yasuda
Kenji
K
Karhanek
Miloslav
M
D004553:Electric Conductivity; D004566:Electrodes; D008422:Materials Testing; D036103:Nanotechnology / Q000295:instrumentation / Q000379:methods; D043942:Nanotubes / Q000737:chemistry*; D010316:Particle Size; D011107:Polylysine / Q000737:chemistry*; D011791:Quartz / Q000737:chemistry*; D012680:Sensitivity and Specificity; D013499:Surface Properties
D011791:Quartz; D011107:Polylysine