title: Value of the innovated technique agarose cell block in improving the sensitivity of urine cytology in cases of bladder carcinoma.
abstract: Proper handling and processing of urine sample can greatly improve diagnostic sensitivity. This work investigates the value of agarose cell block technique in processing urine samples simultaneously for light and electron microscopic examination, with the prospect to enhance the quality of diagnosis. The material of this study consisted of 45 voided urine samples, processed for the performance of Papanicolaou-stained urine smears, agarose cell blocks paraffin sections stained with hematoxylin & eosin, and electron microscopy-contrasted ultrathin sections. The studied technique increases the sensitivity of urine cytology and opens a new prospect for cytomorphological study.
authors.affiliation: Electron Microscopy Department, Pathology, Theodor Bilharz Research Institute, Guiza, Egypt. Mansy_11@hotmail.com
authors.forename: Soheir S
authors.initials: SS
authors.lastname: Mansy
authors.forename: Mahmoud A
authors.initials: MA
authors.lastname: Abbas
authors.forename: Hoda A
authors.initials: HA
authors.lastname: Yehia
authors.forename: Samia M
authors.initials: SM
authors.lastname: Abdelrazik
authors.forename: Lobna Y
authors.initials: LY
authors.lastname: Ghanem
authors.forename: Tarek M
authors.initials: TM
authors.lastname: Amin
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis* / Q000652:urine; D003581:Cytodiagnosis / Q000379:methods; D006801:Humans; D008854:Microscopy, Electron / Q000379:methods*; D011237:Predictive Value of Tests; D015203:Reproducibility of Results; D012685:Sepharose; D016610:Tissue Embedding / Q000379:methods*; D001749:Urinary Bladder Neoplasms / Q000175:diagnosis* / Q000652:urine; D014556:Urine / Q000166:cytology*
chemical_list: D012685:Sepharose