title: Postoperative changes in remnant medial segment parenchyma of living donor livers after procurement of left lateral segment graft.
abstract: OBJECTIVE
  Procurement of left lateral segment (LLS) graft usually resulted in uneventful atrophy of the remnant medial segment parenchyma (RMSP) in living donors, but duct dilatation was often detected in the RMSP. We tried to clarify the postoperative atrophic sequences of the RMSP.
  
  
  METHODS
  We analyzed clinical profiles of 33 LLS graft donors out of 362 living donors from January 2002 to December 2003. LLS grafts were divided into type 1 (classical LLS, n= 18), type 2 (intermediately extended LLS, n=8), and type 3 (extended LLS similar to left lobe without middle hepatic vein trunk, n= 7).
  
  
  RESULTS
  On 1-week dynamic computed tomography, early extensive hyperattenuation indicating interlobar arterial collaterals (ILAC) was observed in 4 (22.2%) donors of type 1 and 2 (25%) donors of type 2 LLS grafts. Peak values of serum liver enzymes were not correlated with the amount of RMSP, but they were exceptionally elevated on poor development of ILAC. Most of RMSP became atrophied within 3 months. Delayed-onset bile leak occurred in a donor, by which we had to resect his functional RMSP after 3 months. ILAC was highly associated with persistent bile production and slow atrophic change at RMSP after LLS graft donation.
  
  
  CONCLUSIONS
  These data suggested that temporary arterial collateral formation worked as a buffering mechanism leading to slow and uneventful degeneration of inflow-deprived hepatic parenchyma.
authors.affiliation: Division of Hepatopancreatobiliary Surgery and Liver Transplantation, Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
authors.forename: Shin
authors.initials: S
authors.lastname: Hwang
authors.forename: Sung-Gyu
authors.initials: SG
authors.lastname: Lee
authors.forename: Young-Joo
authors.initials: YJ
authors.lastname: Lee
authors.forename: Kwang-Min
authors.initials: KM
authors.lastname: Park
authors.forename: Chul-Soo
authors.initials: CS
authors.lastname: Ahn
authors.forename: Ki-Hun
authors.initials: KH
authors.lastname: Kim
mesh_terms: D000328:Adult; D001284:Atrophy; D003097:Collateral Circulation; D005260:Female; D006498:Hepatectomy; D006801:Humans; D008099:Liver / Q000000981:diagnostic imaging / Q000473:pathology*; D008111:Liver Function Tests; D016031:Liver Transplantation; D019520:Living Donors; D008297:Male; D008875:Middle Aged; D011184:Postoperative Period; D014057:Tomography, X-Ray Computed