title: [Pituitary apoplexy. Report of 25 patients].
abstract: A series of 25 patients with a clinical diagnosis of pituitary apoplexy (PA) is reviewed. It included 14 men and 11 women aged between 20 to 79 years (mean age: 54 years). Twenty-two patients did not know that they had a pituitary tumor when the apoplexy occurred. A precipitating event was found in 3 cases. Symptoms and signs ranged from isolated ocular paresis to a deep coma. Seventeen patients experienced a decrease in their visual acuity. CTscan and MRI showed a pituitary adenoma in all cases, a hemorrhage was also present in 10 out of the 24 CTscans, and in all the 8 MRI performed. Twenty patients underwent surgery; 18 of them by a transsphenoidal approach. A complete recovery of visual acuity was observed in 75% of patients operated within the week following the onset of symptoms, and in 56% of patients operated later on. There was no case of complete visual recovery among the blind patients. Pituitary apoplexy is a clinical concept. It applies only to symptomatic cases. It is generally a complication of a pituitary adenoma which is in most cases unknown. There are different degrees of severity; PA can even be life-threatening. The principal aim of surgery in the acute phase is the improvement of visual prognosis. In our series, blind patients or those with a history of visual loss for more than a week or with a blindness had a poorer prognosis.
authors.affiliation: Service de Neurochirurgie (Pr Khaldi), Institut National de Neurologie, Rue Jebbari, 1007 La Rabta/Tunis, Tunisie. kbenhamouda@lycos.com
authors.forename: M
authors.initials: M
authors.lastname: Khaldi
authors.forename: K
authors.initials: K
authors.lastname: Ben Hamouda
authors.forename: H
authors.initials: H
authors.lastname: Jemel
authors.forename: J
authors.initials: J
authors.lastname: Kallel
authors.forename: I
authors.initials: I
authors.lastname: Zemmel
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D010899:Pituitary Apoplexy / Q000175:diagnosis / Q000628:therapy; D014057:Tomography, X-Ray Computed