Selective detection method derived from a controlled diffusion process at metal-modified diamond electrodes.
A novel, selective methodology is derived based on the difference between the diffusion processes at microelectrodes (i.e., hemispherical diffusion) and the macroelectrode (i.e., linear diffusion) in a metal-implanted boron-doped diamond electrode (metal-BDDs). As an example, the selective detection of glucose in a solution containing interference species such as ascorbic acid and uric acid is demonstrated. The electrochemical properties of BDD, which are low background current, extremely high stability, and (especially) inactivity toward glucose, play an important role in realizing these differences in the diffusion characteristics. The present methodology can be applied not only to selective glucose detection by the metal-BDD system but also to other selective detection systems.
Watanabe
Takeshi
T
Department of Chemistry, Keio University, 3-14-1 Hiyoshi, Yokohama 223-8522, Japan.
Ivandini
Tribidasari A
TA
Makide
Yoshihiro
Y
Fujishima
Akira
A
Einaga
Yasuaki
Y
D001205:Ascorbic Acid / Q000737:chemistry; D015374:Biosensing Techniques; D018130:Diamond / Q000737:chemistry*; D004058:Diffusion; D004563:Electrochemistry; D004566:Electrodes; D005947:Glucose / Q000032:analysis*; D008670:Metals / Q000737:chemistry*; D012680:Sensitivity and Specificity; D013499:Surface Properties; D013997:Time Factors; D014527:Uric Acid / Q000737:chemistry
D008670:Metals; D014527:Uric Acid; D018130:Diamond; D005947:Glucose; D001205:Ascorbic Acid