title: [Human and canine American cutaneous leishmaniasis in Mariluz, Paraná State, Brazil].
abstract: An outbreak of American cutaneous leishmaniasis was reported in 2002 in Mariluz, northwestern Paraná State, Brazil. Of 38 humans who were investigated, four had healed lesions, ten showed lesions in the healing process, and 24 had active lesions. Of the 126 dogs, 20 (15.9%) presented suggestive lesions and 24 (19%) had positive serology. Parasites isolated from two patients and three dogs were identified as Leishmania (Viannia) braziliensis serodeme I. The captured sand flies were identified as Nyssomyia whitmani, N. neivai, and Migonemyia migonei. Considering that the region where the cases occurred is similar to other old human settlements in Paraná State, the environmental alterations and remaining forests facilitate the maintenance of the parasite's enzootic cycle and transmission to humans and domestic animals, thereby maintaining the endemicity of American cutaneous leishmaniasis.
authors.affiliation: Departamento de Análises Clínicas, Universidade Estadual de Maringá, Maringá, Brasil. mvclonardoni@uem.br
authors.forename: Maria Valdrinez Campana
authors.initials: MV
authors.lastname: Lonardoni
authors.forename: Thaís Gomes Verzignassi
authors.initials: TG
authors.lastname: Silveira
authors.forename: Waneska Alexandra
authors.initials: WA
authors.lastname: Alves
authors.forename: Ana Nilce Silveira
authors.initials: AN
authors.lastname: Maia-Elkhoury
authors.forename: Umberto Assis
authors.initials: UA
authors.lastname: Membrive
authors.forename: Norberto Assis
authors.initials: NA
authors.lastname: Membrive
authors.forename: Gesse
authors.initials: G
authors.lastname: Rodrigues
authors.forename: Nélio
authors.initials: N
authors.lastname: Reis
authors.forename: Paulo Donizete
authors.initials: PD
authors.lastname: Zanzarini
authors.forename: Edna
authors.initials: E
authors.lastname: Ishikawa
authors.forename: Ueslei
authors.initials: U
authors.lastname: Teodoro
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000818:Animals; D000913:Antibodies, Protozoan / Q000097:blood*; D001938:Brazil / Q000453:epidemiology; D002648:Child; D002675:Child, Preschool; D004196:Disease Outbreaks; D004283:Dog Diseases / Q000175:diagnosis / Q000453:epidemiology*; D004285:Dogs; D005260:Female; D019084:Fluorescent Antibody Technique, Indirect; D006801:Humans; D007303:Insect Vectors; D007428:Intradermal Tests; D007892:Leishmania braziliensis / Q000276:immunology*; D016773:Leishmaniasis, Cutaneous / Q000175:diagnosis / Q000453:epidemiology* / Q000662:veterinary*; D008297:Male; D008875:Middle Aged; D012424:Rural Population
chemical_list: D000913:Antibodies, Protozoan