[Mechanism of wenpi decoction delaying progression of chronic renal failure].
Wenpi decoction ameliorates the harmful factors of chronic renal failure, such as mesangial matrix and its cytokines, nuclear factor, endothelium-dependent relaxing factor, oxidative free raidical, apoptosis, lipide, protein, and blood rheology. Wenpi decoction is an effective agent for delaying the progression of chronic renal failure.
Zhang
Jie
J
Department of Traditional Chinese Medicine, Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing 210008, China.
Wan
Yi-Gang
YG
D000818:Animals; D017209:Apoptosis / Q000187:drug effects; D049109:Cell Proliferation / Q000187:drug effects; D018450:Disease Progression; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification / Q000494:pharmacology*; D045462:Endothelium-Dependent Relaxing Factors / Q000378:metabolism; D007676:Kidney Failure, Chronic / Q000378:metabolism / Q000473:pathology; D050527:Mesangial Cells / Q000166:cytology; D016328:NF-kappa B / Q000378:metabolism; D010946:Plants, Medicinal / Q000737:chemistry; D013482:Superoxide Dismutase / Q000378:metabolism
D004338:Drug Combinations; D004365:Drugs, Chinese Herbal; D045462:Endothelium-Dependent Relaxing Factors; D016328:NF-kappa B; C523153:wenpi decoction; D013482:Superoxide Dismutase