title: Cardiopulmonary exercise testing in children and adolescents with asthma who report symptoms of exercise-induced bronchoconstriction.
abstract: Patients with asthma often report symptoms of exercise-induced bronchoconstriction. We performed cardiopulmonary exercise testing to establish the cause of exercise limitation in patients with asthma, under treatment, who reported symptoms of exercise-induced bronchoconstriction. Ten of the 42 patients meeting criteria for inclusion in our study (24%) developed exercise-induced bronchoconstriction. Exercise limitation without exercise-induced bronchoconstriction was found in both obese and non-obese patients, suggesting that poor fitness is a problem independent of body habitus. Including cardiopulmonary exercise testing in the management of children with suspected exercise-induced bronchoconstriction would provide a better understanding of the etiology of their symptoms and facilitate more appropriate treatment.
authors.affiliation: Division of Pediatric Respiratory and Sleep Medicine, Department of Pediatrics, Children's Hospital at Montefiore, Albert Einstein College of Medicine, Bronx, New York, USA. bennyjoyner@gmail.com
authors.forename: Benny L
authors.initials: BL
authors.lastname: Joyner
authors.forename: Elizabeth K
authors.initials: EK
authors.lastname: Fiorino
authors.forename: Esther
authors.initials: E
authors.lastname: Matta-Arroyo
authors.forename: Joshua P
authors.initials: JP
authors.lastname: Needleman
mesh_terms: D000293:Adolescent; D001249:Asthma / Q000150:complications / Q000503:physiopathology*; D001250:Asthma, Exercise-Induced / Q000150:complications / Q000175:diagnosis*; D015992:Body Mass Index; D016084:Bronchoconstriction; D002648:Child; D015444:Exercise; D005080:Exercise Test; D005260:Female; D005541:Forced Expiratory Volume; D006801:Humans; D008297:Male; D009765:Obesity / Q000150:complications / Q000503:physiopathology; D010101:Oxygen Consumption; D013147:Spirometry; D014797:Vital Capacity