Hypertensive crisis, hepatitis B virus and polyarteritis nodosa in a child.
We report on a case of hepatitis B virus-related polyarteritis nodosa (PAN) in a 4-year-old Turkish boy who was first admitted because of severe arterial hypertension. The diagnosis of PAN was provided by conventional renal arteriography and the child was successfully treated with intensive sequential therapy combining short-term prednisone, plasma exchange and interferon-alpha-2b. Nine years later, he had no sign of PAN, normal blood pressure and normal renal function in the absence of any treatment.
Belot
Alexandre
A
Néphrologie Pédiatrique, Hôpital Edouard Herriot, Lyon, France.
Ranchin
Bruno
B
Canterino
Isabelle
I
Trepo
Christian
C
Dubourg
Laurence
L
Cochat
Pierre
P
D000792:Angiography; D000998:Antiviral Agents / Q000627:therapeutic use; D002675:Child, Preschool; D005938:Glucocorticoids / Q000627:therapeutic use; D006509:Hepatitis B / Q000150:complications / Q000628:therapy; D006515:Hepatitis B virus; D006801:Humans; D006974:Hypertension, Malignant / Q000150:complications / Q000628:therapy / Q000821:virology*; D000077190:Interferon alpha-2; D016898:Interferon-alpha / Q000627:therapeutic use; D007668:Kidney / Q000098:blood supply / Q000473:pathology; D008297:Male; D010951:Plasma Exchange; D010488:Polyarteritis Nodosa / Q000150:complications / Q000628:therapy / Q000821:virology*; D011241:Prednisone / Q000627:therapeutic use; D011994:Recombinant Proteins
D000998:Antiviral Agents; D005938:Glucocorticoids; D000077190:Interferon alpha-2; D016898:Interferon-alpha; D011994:Recombinant Proteins; D011241:Prednisone