[Therapeutic effects of Jinqi Jiangtang tablet on women with polycystic ovary syndrome].
OBJECTIVE
To observe the therapeutic effects of Jinqi Jiangtang Tablet (JQJTT), a commonly prescribed recipe for type 2 diabetes in traditional Chinese medicine, on obese women with polycystic ovary syndrome (PCOS).


METHODS
Twenty-four obese women with PCOS were prescribed JQJTT for 3 months and the changes of carbohydrate metabolism and biochemical indicators, including menstrual cycle, body mass index (BMI), the level of blood sex hormone, area under curve (AUC) of glucose and insulin during oral glucose tolerance test (OGTT), and testosterone responses during human chorionic gonadotrophin stimulation ovary test were observed.


RESULTS
After treatment, there were significantly reductions in BMI (P<0.05), serum glucose level at 30 min during OGTT (P<0.05) and testosterone levels at eighteen hours during human chorionic gonadotrophin stimulation ovary test (P<0.05). In addition, nine patients had improved cycles among sixteen completed patients, and one patient with clomifene resistance got pregnant with response to clomifene treatment.


CONCLUSIONS
The beneficial effects of JQJTT may result from improvement of carbohydrate metabolism and reduction in androgen biosynthesis in women with PCOS.
Hou
Li-Hui
LH
Department of Obstetrics and Gynecology, The First Affiliated Hospital, Heilongjiang University of Chinese Medicine, Harbin, Heilongjiang Province 150040, China.
Yang
Xin-Ming
XM
Erkkola
Risto
R
Wu
Xiao-Ke
XK
D000293:Adolescent; D000328:Adult; D015992:Body Mass Index; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D005951:Glucose Tolerance Test; D006801:Humans; D008517:Phytotherapy; D011085:Polycystic Ovary Syndrome / Q000097:blood / Q000188:drug therapy*; D013607:Tablets; D013739:Testosterone / Q000097:blood*
D004365:Drugs, Chinese Herbal; D013607:Tablets; C527173:jinqi jiantang; D013739:Testosterone