title: Synthesis of the mycolactone core by ring-closing metathesis.
abstract: The undecenolide core of mycolactone was synthesized by ring-closing metathesis and the structure confirmed using single-crystal X-ray diffraction techniques.
authors.affiliation: Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA 92093-0358, USA.
authors.forename: Matthew D
authors.initials: MD
authors.lastname: Alexander
authors.forename: Shaun D
authors.initials: SD
authors.lastname: Fontaine
authors.forename: James J
authors.initials: JJ
authors.lastname: La Clair
authors.forename: Antonio G
authors.initials: AG
authors.lastname: Dipasquale
authors.forename: Arnold L
authors.initials: AL
authors.lastname: Rheingold
authors.forename: Michael D
authors.initials: MD
authors.lastname: Burkart
mesh_terms: D001427:Bacterial Toxins / Q000138:chemical synthesis* / Q000737:chemistry; D018360:Crystallography, X-Ray; D003500:Cyclization; D018942:Macrolides; D009682:Magnetic Resonance Spectroscopy; D008958:Models, Molecular; D008968:Molecular Conformation; D012680:Sensitivity and Specificity; D013237:Stereoisomerism
chemical_list: D001427:Bacterial Toxins; D018942:Macrolides; C117218:mycolactone