title: Outcome of surgical intervention for isolated intrathoracic lymph node metastasis from infradiaphragmatic malignancy: report of two cases.
abstract: We report 2 cases with isolated intrathoracic lymph node involvement. This is an unusual manifestation of metastatic spread from an extrathoracic malignancy. Case 1 was a 47-year-old female with a history of radical hysterectomy for cervical cancer of the uterus. Left intrathoracic lymphadenopathy was detected during follow-up. These lesions were surgically removed and diagnosed as multiple lymph node metastases. Two years later, right intrathoracic lymphadenopathy was evident and excised again. Eight months after the re-thoracotomy, retroperitoneal recurrence appeared and she died of the disease. Case 2 was a 41-year-old female with a history of resection of sigmoid colon cancer with liver metastases. A solitary nodule in the left upper lobe was shown by a chest computed tomography (CT). Left upper lobectomy was performed and the lesion was diagnosed as a solitary lymph node metastasis. She has had no recurrence for 3 years since thoracotomy.
authors.affiliation: Department of Thoracic Surgery, Nara Medical Center, 2-789 Shichijo, Nara, Japan.
authors.forename: Takeshi
authors.initials: T
authors.lastname: Kawaguchi
authors.forename: Keiji
authors.initials: K
authors.lastname: Kushibe
authors.forename: Michitaka
authors.initials: M
authors.lastname: Kimura
authors.forename: Makoto
authors.initials: M
authors.lastname: Takahama
authors.forename: Takashi
authors.initials: T
authors.lastname: Tojo
authors.forename: Yasunori
authors.initials: Y
authors.lastname: Enomoto
authors.forename: Akitaka
authors.initials: A
authors.lastname: Nonomura
authors.forename: Shigeki
authors.initials: S
authors.lastname: Taniguchi
mesh_terms: D000328:Adult; D001706:Biopsy; D002294:Carcinoma, Squamous Cell / Q000556:secondary*; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008197:Lymph Node Excision / Q000379:methods*; D008198:Lymph Nodes / Q000473:pathology* / Q000601:surgery; D008207:Lymphatic Metastasis; D008875:Middle Aged; D012811:Sigmoid Neoplasms / Q000473:pathology*; D013908:Thoracotomy / Q000379:methods*; D013909:Thorax; D014057:Tomography, X-Ray Computed; D002583:Uterine Cervical Neoplasms / Q000473:pathology*