title: Acute toxicity, behavioral changes, and histopathological effects of deltamethrin on tissues (gills, liver, brain, spleen, kidney, muscle, skin) of Nile tilapia (Oreochromis niloticus L.) fingerlings.
abstract: Deltamethrin, a synthetic pyrethroid contaminating aquatic ecosystems as a potential toxic pollutant, was investigated in the present study for acute toxicity. The purpose of this study was to evaluate LC(50) values of deltamethrin on Nile tilapia (Oreochromis niloticus L.) fingerlings and investigate histopathological responses of fish exposed to deltamethrin. The 48 h LC(50) value for Nile tilapia fingerlings was estimated as 4.85 microg/L using static test system. In addition, behavioral changes at each deltamethrin concentration were observed closely. All fish, exposed to 5 microg/L deltamethrin revealed severe morphological alterations in the gills and liver. In the gills hyperemia, fusion of secondary lamellae and telangiectasis were observed; whereas hydropic degenerations in liver were observed in all examined fish. The results are significant for reporting acute deltamethrin toxicity in terms of behavioral and histopathological changes: Deltamethrin is highly toxic to fingerlings.
authors.affiliation: Department of Pathology, Faculty of Veterinary Medicine, Ankara University, Dişkapi, Ankara 06110, Turkey.
authors.forename: M Ziynet
authors.initials: MZ
authors.lastname: Yildirim
authors.forename: A Cağlan Karasu
authors.initials: AC
authors.lastname: Benli
authors.forename: Mahmut
authors.initials: M
authors.lastname: Selvi
authors.forename: Ayhan
authors.initials: A
authors.lastname: Ozkul
authors.forename: Figen
authors.initials: F
authors.lastname: Erkoç
authors.forename: Oner
authors.initials: O
authors.lastname: Koçak
mesh_terms: D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects*; D023681:Cichlids / Q000033:anatomy & histology / Q000254:growth & development / Q000378:metabolism*; D004784:Environmental Monitoring / Q000379:methods; D005880:Gills / Q000187:drug effects / Q000473:pathology; D007306:Insecticides / Q000633:toxicity*; D007668:Kidney / Q000187:drug effects / Q000473:pathology; D008099:Liver / Q000187:drug effects / Q000473:pathology; D009132:Muscles / Q000187:drug effects / Q000473:pathology; D009570:Nitriles / Q000633:toxicity*; D011722:Pyrethrins / Q000633:toxicity*; D012867:Skin / Q000187:drug effects / Q000473:pathology; D013154:Spleen / Q000187:drug effects / Q000473:pathology; D023382:Toxicity Tests, Acute
chemical_list: D007306:Insecticides; D009570:Nitriles; D011722:Pyrethrins; C017180:decamethrin