The anterior visceral endoderm-turning heads.
The Anterior Visceral Endoderm is an extraembryonic tissue that plays a pivotal role during embryogenesis, being responsible for the proper orientation of the anterior-posterior axis of the embryo and for appropriate pattering of adjacent embryonic tissue. In this review I discuss the formation and migration of the AVE, and attempt to place some recent findings in the context of a working model.
Srinivas
Shankar
S
Department of Physiology, Anatomy & Genetics, University of Oxford, Oxford, United Kingdom. shankar.srinivas@anat.ox.ac.uk
D000818:Animals; D019521:Body Patterning / Q000502:physiology*; D002465:Cell Movement / Q000502:physiology*; D004707:Endoderm / Q000166:cytology* / Q000502:physiology*; D005321:Extraembryonic Membranes / Q000196:embryology*; D051379:Mice; D008954:Models, Biological