In the eye of the beholder.
Scientific journals and regulatory agencies want reliable clinical trials, but the definition of 'reliable' isn't necessarily the same for both parties.
D002986:Clinical Trials as Topic; D017277:Drug Approval; D015507:Drugs, Investigational; D006801:Humans; D015203:Reproducibility of Results; D014481:United States; D014486:United States Food and Drug Administration
D015507:Drugs, Investigational