Reversible myeloradiculopathy due to Mycoplasma pneumoniae.
A 22-year-old man presented with flaccid paraparesis and a thoracic sensory level in the context of a recent respiratory illness. Investigations established cerebrospinal pleocytosis with elevated protein, and subsequent serological testing confirmed raised antibody titres to Mycoplasma pneumoniae. Nerve conduction studies established that H-reflexes were prolonged and somatosensory evoked responses were delayed from the lower limbs bilaterally. Although imaging of the spinal cord revealed no abnormality, clinical and neurophysiological findings were consistent with a myeloradiculopathy. The patient was treated with pulse intravenous methylprednisone and underwent complete recovery over a 4-week period.
Hsing
Joanna
J
Institute of Neurological Sciences, Prince of Wales Hospital, Sydney, Australia.
Welgampola
Miriam
M
Kiernan
Matthew C
MC
D000328:Adult; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage / Q000627:therapeutic use; D005073:Evoked Potentials, Somatosensory / Q000502:physiology; D006181:H-Reflex / Q000502:physiology; D006801:Humans; D007275:Injections, Intravenous; D008297:Male; D008775:Methylprednisolone / Q000008:administration & dosage / Q000627:therapeutic use; D009177:Mycoplasma pneumoniae; D009431:Neural Conduction / Q000502:physiology; D009460:Neurologic Examination; D020335:Paraparesis / Q000209:etiology; D011019:Pneumonia, Mycoplasma / Q000134:cerebrospinal fluid / Q000150:complications* / Q000382:microbiology; D011843:Radiculopathy / Q000188:drug therapy / Q000209:etiology*; D012684:Sensory Thresholds / Q000502:physiology
D000893:Anti-Inflammatory Agents; D008775:Methylprednisolone