The risk of breast cancer in relation to health habits and occupational exposures.
BACKGROUND
The age-adjusted incidence rate of breast cancer has increased for Israeli women. Our aim was to explore the hypothesis that occupational exposures are important risk factors, taking into consideration main known risk factors.


METHODS
The study population included 326 breast cancer cases from one hospital in the center of the country and 413 women without known diagnosis of cancer. Every participant was interviewed using a structured questionnaire.


RESULTS
We found that working in textile and clothing and in various industries, OR (95% confidence interval), 1.8 (1.1-3.0), 4.3 (2.0-9.3) respectively, and exposure to ionizing radiation OR 5.3 (2.4-14.1) as well as age and having a family history of breast cancer significantly increased the risk of developing breast cancer. Administrative work, adherence to high fiber diet and low salt diet significantly lowered the risk of breast cancer.


CONCLUSIONS
Our study supported the assumption that occupational exposure may contribute to the etiology of breast cancer.
Shaham
Judith
J
Occupational Cancer Department, National Institute of Occupational and Environmental Health, Raanana, Israel. yshaham@bezeqint.net
Gurvich
Rachel
R
Goral
Aviva
A
Czerniak
Abraham
A
D000367:Age Factors; D000368:Aged; D001943:Breast Neoplasms / Q000453:epidemiology*; D016022:Case-Control Studies; D004032:Diet; D005260:Female; D006306:Health Surveys; D006801:Humans; D007557:Israel / Q000453:epidemiology; D008019:Life Style; D008875:Middle Aged; D015999:Multivariate Analysis; D016273:Occupational Exposure / Q000009:adverse effects* / Q000706:statistics & numerical data*; D009790:Occupations / Q000706:statistics & numerical data*; D016017:Odds Ratio; D011839:Radiation, Ionizing; D012307:Risk Factors; D013783:Textile Industry