[Toxicity assessment of the vegetable emulsifier- the aqueous extract from the common soapwort roots].
Within the limits of experimental observation the assessment of acute and subacute safety of an aqueous extract from Acanthophyllum roots with a solids content of 7%, used as an emulsifier has been manufactured by production of emulsion products. Acute toxicity (LD50) AEAR, probed on mice-male; has allowed to refer to an emulsifier to a class of nontoxic substance. The assessmentof subacute toxicity of an extract (injection in a food allowance within 30 days in a recommended dose--5 ml on 100 g of a standard food allowance) was spent on laboratory rats. Extent of toxicity of a specimen judged on the general state of animals, a body mass dynamics, internals masses, to biochemical parameters of blood plasma, parameters of a peripheric blood, a morphological pattern of an internals. Comparative analysis of results allows to expel toxic effect AEAR in the recommended dose on an organism of animals.
Iudina
T P
TP
Tsybul'ko
E I
EI
Cherevan
E I
EI
Babin
Iu V
IuV
Kropotov
A V
AV
Plaksen
N V
NV
Khil'chenko
N S
NS
D000818:Animals; D001769:Blood / Q000378:metabolism; D004305:Dose-Response Relationship, Drug; D045703:Emulsifying Agents / Q000633:toxicity*; D007928:Lethal Dose 50; D008297:Male; D051379:Mice; D010936:Plant Extracts / Q000633:toxicity*; D018517:Plant Roots / Q000737:chemistry; D051381:Rats; D017208:Rats, Wistar; D029750:Saponaria / Q000737:chemistry*; D018675:Toxicity Tests; D014675:Vegetables / Q000737:chemistry*
D045703:Emulsifying Agents; D010936:Plant Extracts