Magnetic resonance imaging volumetric analysis of the putamen in children with ADHD: combined type versus control.
OBJECTIVE
Volumetric differences in the putamen of boys with ADHD combined subtype with psychopathic traits and controls are investigated.


METHODS
The putamen in 24 archival magnetic resonance imaging scans of 12 boys in residential treatment with symptoms of ADHD and psychopathic traits and 12 community control boys are analyzed using Display software.


RESULTS
There are no differences found in the total, left, and right putamen volumes across the ADHD or control group. A significant reversal of asymmetry across groups is found; children with ADHD more frequently have a smaller left putamen than right. In contrast, the control group more frequently has a smaller right than left putamen.


CONCLUSIONS
A reversal of symmetry in the putamen (as found in the caudate) may relate to ADHD symptomology as well as to psychopathic traits.
Wellington
Tasha McMahon
TM
Department of Psychology, University of Texas, Austin, TX 78712, USA. mcmahont@mail.utexas.edu
Semrud-Clikeman
Margaret
M
Gregory
Amanda Louise
AL
Murphy
Jennifer Mary
JM
Lancaster
Jack Lynn
JL
D000293:Adolescent; D000987:Antisocial Personality Disorder / Q000175:diagnosis* / Q000523:psychology / Q000628:therapy; D001289:Attention Deficit Disorder with Hyperactivity / Q000175:diagnosis* / Q000523:psychology / Q000628:therapy; D015897:Comorbidity; D004292:Dominance, Cerebral / Q000502:physiology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D010552:Personality Assessment; D011699:Putamen / Q000473:pathology*; D012016:Reference Values; D012114:Residential Treatment