title: Selective detection method derived from a controlled diffusion process at metal-modified diamond electrodes.
abstract: A novel, selective methodology is derived based on the difference between the diffusion processes at microelectrodes (i.e., hemispherical diffusion) and the macroelectrode (i.e., linear diffusion) in a metal-implanted boron-doped diamond electrode (metal-BDDs). As an example, the selective detection of glucose in a solution containing interference species such as ascorbic acid and uric acid is demonstrated. The electrochemical properties of BDD, which are low background current, extremely high stability, and (especially) inactivity toward glucose, play an important role in realizing these differences in the diffusion characteristics. The present methodology can be applied not only to selective glucose detection by the metal-BDD system but also to other selective detection systems.
authors.affiliation: Department of Chemistry, Keio University, 3-14-1 Hiyoshi, Yokohama 223-8522, Japan.
authors.forename: Takeshi
authors.initials: T
authors.lastname: Watanabe
authors.forename: Tribidasari A
authors.initials: TA
authors.lastname: Ivandini
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Makide
authors.forename: Akira
authors.initials: A
authors.lastname: Fujishima
authors.forename: Yasuaki
authors.initials: Y
authors.lastname: Einaga
mesh_terms: D001205:Ascorbic Acid / Q000737:chemistry; D015374:Biosensing Techniques; D018130:Diamond / Q000737:chemistry*; D004058:Diffusion; D004563:Electrochemistry; D004566:Electrodes; D005947:Glucose / Q000032:analysis*; D008670:Metals / Q000737:chemistry*; D012680:Sensitivity and Specificity; D013499:Surface Properties; D013997:Time Factors; D014527:Uric Acid / Q000737:chemistry
chemical_list: D008670:Metals; D014527:Uric Acid; D018130:Diamond; D005947:Glucose; D001205:Ascorbic Acid