Concise synthesis of the (+/-)-Nb-desmethyl-meso-chimonanthine.
The first total synthesis of the bis-pyrroloindoline alkaloid (+/-)-Nb-desmethyl-meso-chimonanthine, having a pseudo C2-symmetry, was realised in a seven-step convergent sequence without the use of protecting groups.
Menozzi
Candice
C
Laboratoire de Chimie Organique associé au CNRS, ESPCI, 10 rue Vauquelin, 75231, Paris Cedex 05, France.
Dalko
Peter I
PI
Cossy
Janine
J
D000470:Alkaloids / Q000138:chemical synthesis* / Q000737:chemistry; D007211:Indoles / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D011758:Pyrroles / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
D000470:Alkaloids; D007211:Indoles; C516206:N(b)-desmethylchimonathine; D011758:Pyrroles