A case of catecholamine and glucocorticoid excess syndrome due to a corticotropin-secreting paraganglioma.
We present a case of a 61-year-old female patient with ectopic corticotropin (ACTH) syndrome, hypopituitarism, and catecholamine excess due to a paraganglioma at the inferior pole of the left kidney. In this article we discuss the hormonal findings in the patient and its consequences, the pitfalls of the endocrine workup, and the results of our immunohistological and molecular studies in more detail.
Willenberg
Holger S
HS
Department of Endocrinology, Diabetes and Rheumatology, University Hospital Düsseldorf, Moorenstr. 5, D-40225 Düsseldorf, Germany. Holger.Willenberg@uni-duesseldorf.de
Feldkamp
Joachim
J
Lehmann
Reiner
R
Schott
Matthias
M
Goretzki
Peter E
PE
Scherbaum
Werner A
WA
D000324:Adrenocorticotropic Hormone / Q000378:metabolism*; D002395:Catecholamines / Q000097:blood* / Q000378:metabolism; D005260:Female; D005938:Glucocorticoids / Q000097:blood* / Q000378:metabolism; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D010235:Paraganglioma / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000378:metabolism; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography
D002395:Catecholamines; D005938:Glucocorticoids; D000324:Adrenocorticotropic Hormone