'Oming in on schistosomes: prospects and limitations for post-genomics.
The recent release of version 3 of the Schistosoma mansoni genome assembly has made a wealth of information available to researchers. Here, progress made in schistosome genomics and post-genomics is considered. The current status of knowledge about the genome, transcriptome, proteome, glycome and immunome is summarized and recent publications briefly reviewed. The prospects for advances in understanding schistosome biology are highlighted. Most importantly, the limitations (which are mostly technical) that need to be addressed before the full potential of the genome database(s) can be realized are emphasized.
Wilson
R Alan
RA
Department of Biology, University of York, PO Box 373, York YO10 5YW, UK. raw3@york.ac.uk
Ashton
Peter D
PD
Braschi
Simon
S
Dillon
Gary P
GP
Berriman
Matthew
M
Ivens
Alasdair
A
D000818:Animals; D005260:Female; D020869:Gene Expression Profiling / Q000662:veterinary; D016678:Genome / Q000235:genetics; D023281:Genomics; D008297:Male; D011134:Polysaccharides / Q000235:genetics; D020543:Proteome / Q000235:genetics; D012547:Schistosoma / Q000235:genetics* / Q000276:immunology / Q000502:physiology; D012550:Schistosoma mansoni / Q000235:genetics / Q000276:immunology / Q000502:physiology
D011134:Polysaccharides; D020543:Proteome