Evaluation of a quick test for C-reactive protein in a pediatric emergency department.
OBJECTIVE
C-reactive protein (CRP) is a reliable laboratory test that is useful in distinguishing between viral and bacterial infection. Although widely used, blood sampling and the need for a well-organized laboratory are limiting factors. Recently, a rapid test for serum CRP (QuickRead CRP) has been developed that can use both venous and capillary blood. The aim of this study was to use QuickRead CRP in our Pediatric Emergency Department and to compare this method with the standard laboratory determination (CRP-lab).


METHODS
All children with fever were given a quick CRP test simultaneously with venous (CRP-V) and capillary blood samples (CRP-C). A total of 127 children were included in the study (median age 2.5 years).


RESULTS
The QuickRead CRP test had an excellent correlation with the standard biochemical determination (CRP-lab). More importantly, there was no difference in determination of CRP in the venous and capillary blood samples. Finally, there was no significant intra-assay variability.


CONCLUSIONS
The QuickRead CRP test is easy to use, provides reliable results and reduces the need for antibacterial therapy.
Papaevangelou
V
V
2nd Department of Pediatrics, University of Athens, Medical School, A. Kyriakou Children's Hospital, Goudi, Greece. vpapaev@med.uoa.gr
Papassotiriou
I
I
Sakou
I
I
Ferentinos
G
G
Liapi
G
G
Kyrka
A
A
Konstantopoulos
A
A
D000293:Adolescent; D001424:Bacterial Infections / Q000175:diagnosis*; D002097:C-Reactive Protein / Q000032:analysis*; D002648:Child; D002675:Child, Preschool; D003955:Diagnostic Tests, Routine / Q000379:methods*; D004636:Emergency Service, Hospital; D006776:Hospitals, Pediatric; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D009391:Nephelometry and Turbidimetry / Q000379:methods; D015203:Reproducibility of Results; D013997:Time Factors; D014777:Virus Diseases / Q000097:blood / Q000175:diagnosis*
D002097:C-Reactive Protein