title: Geode of the femur: an uncommon manifestation potentially reflecting the pathogenesis of rheumatoid arthritis.
abstract: Geodes are noted frequently in rheumatoid arthritis (RA), but large geodes of the femur are uncommon. We describe a patient with RA and a large geode in his femur; histological findings were consistent with a rheumatoid nodule and chronically inflamed synovium. We review the literature of large femoral geodes and what this particular manifestation may reflect about the pathogenesis of RA.
authors.affiliation: Division of Rheumatology, Department of Radiology, Cedars-Sinai Medical Center, Los Angeles, California 90048, USA.
authors.forename: Wonuk
authors.initials: W
authors.lastname: Lee
authors.forename: Michael R
authors.initials: MR
authors.lastname: Terk
authors.forename: Bing
authors.initials: B
authors.lastname: Hu
authors.forename: Elayne K
authors.initials: EK
authors.lastname: Garber
authors.forename: Michael H
authors.initials: MH
authors.lastname: Weisman
mesh_terms: D001172:Arthritis, Rheumatoid / Q000150:complications* / Q000473:pathology / Q000601:surgery; D019644:Arthroplasty, Replacement, Hip; D001845:Bone Cysts / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology; D005269:Femur / Q000473:pathology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D011859:Radiography; D013585:Synovitis / Q000000981:diagnostic imaging / Q000209:etiology / Q000473:pathology; D016896:Treatment Outcome