title: Coronary flow reserve is also impaired in patients with subclinical hypothyroidism.
abstract: The diagnosis of subclinical hypothyroidism and detection of its effects on cardiovascular system is important. Also, the patients with subclinical hypothyroidism even at the very early stage are at increased risk for developing atherosclerosis. We evaluated coronary microvascular circulation and endothelial dysfunction of epicardial coronary arteries by the measurement of coronary flow velocity reserve via a non invasive technique, transthoracic Doppler echocardiography in subclinical hypothyroidism. Coronary flow reserve in patients with subclinical hypothyroidism such as in overt hypothyroidism was lower than that of euthyroid subject. As a conclusion, endothelial and microvascular dysfunction, which are early harbingers of atherosclerosis, are shown in overt and subclinical hypothyroidism.
authors.forename: Huseyin
authors.initials: H
authors.lastname: Oflaz
authors.forename: Ramazan
authors.initials: R
authors.lastname: Kurt
authors.forename: Arif
authors.initials: A
authors.lastname: Cimen
authors.forename: Ali
authors.initials: A
authors.lastname: Elitok
authors.forename: Imran
authors.initials: I
authors.lastname: Onur
authors.forename: Ebru
authors.initials: E
authors.lastname: Golcuk
authors.forename: Mustafa
authors.initials: M
authors.lastname: Demirturk
authors.forename: Serap
authors.initials: S
authors.lastname: Batmaz
authors.forename: Erdem
authors.initials: E
authors.lastname: Kasikcioglu
mesh_terms: D001783:Blood Flow Velocity / Q000502:physiology*; D016022:Case-Control Studies; D003326:Coronary Circulation / Q000502:physiology*; D015150:Echocardiography, Doppler; D004730:Endothelium, Vascular / Q000000981:diagnostic imaging / Q000503:physiopathology; D005260:Female; D006706:Homeostasis / Q000502:physiology; D006801:Humans; D007037:Hypothyroidism / Q000097:blood / Q000503:physiopathology*; D008297:Male; D008833:Microcirculation / Q000000981:diagnostic imaging / Q000503:physiopathology; D008875:Middle Aged; D013972:Thyrotropin / Q000097:blood; D013974:Thyroxine / Q000097:blood
chemical_list: D013972:Thyrotropin; D013974:Thyroxine