[Case of eosinophilic bronchitis and bronchiolitis associated with increased level of serum CEA in asthmatics].
A 50-year-old asthmatic woman showed peripheral blood eosinophilia, significantly increased level of CEA in serum (102.5ng/ml), and atelectasis of the right middle lobe on chest radiograph and CT. The level of CEA subsequently increased further, and then decreased with systemic corticosteroid therapy. Pathological findings of surgically biopsied lung showed eosinophilic broncho-bronchiolitis, without malignant cells. Two years later, chest CT demonstrated various findings such as mucoid impaction, peripheral bronchiectasis and centrilobular nodules, but allergic bronchopulmonary mycosis was not proved. These findings suggest that the eosinophilic bronchiolar inflammation in bronchial asthma caused an increase in serum CEA levels and various findings on chest CT.
Tsuburai
Takahiro
T
Clinical Research Center for Allergy and Rheumatology, National Hospital Organization, Sagamihara National Hospital.
Kawabata
Yoshinori
Y
Tsurikisawa
Naomi
N
Mitomi
Hiroyuki
H
Oshikata
Chiyako
C
Ono
Emiko
E
Ohtomo
Mamoru
M
Maeda
Yuji
Y
Taniguchi
Masami
M
Akiyama
Kazuo
K
D001249:Asthma / Q000150:complications* / Q000000981:diagnostic imaging; D001988:Bronchiolitis / Q000000981:diagnostic imaging / Q000209:etiology*; D002272:Carcinoembryonic Antigen / Q000097:blood*; D004802:Eosinophilia / Q000000981:diagnostic imaging / Q000209:etiology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D014057:Tomography, X-Ray Computed
D002272:Carcinoembryonic Antigen