Urinary hesitancy and retention during treatment with sertraline.
We report the cases of two women who began to experience urinary hesitancy and retention after starting treatment with sertraline for depression. Discontinuation of the drug resulted in complete symptom relief. Serotonergic neurons are involved at several levels in control of the lower urinary tract. Retention is apparently an uncommon complication of sertraline. Discontinuation should be considered for patients presenting with voiding difficulties.
Lowenstein
L
L
Division of Female Pelvic Medicine and Reconstructive Surgery, Loyola Medical Center, 2160 South First Avenue, Maywood, IL 60153, USA. llowenstein@lumc.edu
Mueller
E R
ER
Sharma
S
S
FitzGerald
M P
MP
D000368:Aged; D005260:Female; D006801:Humans; D008875:Middle Aged; D017367:Selective Serotonin Reuptake Inhibitors / Q000009:adverse effects*; D020280:Sertraline / Q000009:adverse effects*; D016055:Urinary Retention / Q000139:chemically induced*
D017367:Selective Serotonin Reuptake Inhibitors; D020280:Sertraline