title: Transfusion support to Dengue patients in a hospital based blood transfusion service in north India.
abstract: We evaluated transfusion requirements in a retrospective study of 245 patients with various categories of Dengue infection. The majority (155/245) of our patients were of the Dengue fever (DF) category. There was no correlation between clinical bleed and platelet count as 81 non-bleeding patients were having counts < 20 x 10(3)/microL. Coagulopathy was observed in 37% of the patients with Dengue hemorrhagic fever or Dengue shock syndrome. A rapid response to platelet and fresh frozen plasma (FFP) transfusion was observed in all cases. However, inappropriate transfusion was a major concern as transfusion of 21.5% platelet concentrates was considered inappropriate.
authors.affiliation: Transfusion Medicine, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow 226014, India. rkcchaud@sgpgi.ac.in
authors.forename: Rajendra
authors.initials: R
authors.lastname: Chaudhary
authors.forename: Dheeraj
authors.initials: D
authors.lastname: Khetan
authors.forename: Seema
authors.initials: S
authors.lastname: Sinha
authors.forename: Pratul
authors.initials: P
authors.lastname: Sinha
authors.forename: Atul
authors.initials: A
authors.lastname: Sonker
authors.forename: Prashant
authors.initials: P
authors.lastname: Pandey
authors.forename: Sudipta Sekhar
authors.initials: SS
authors.lastname: Das
authors.forename: Prashant
authors.initials: P
authors.lastname: Agarwal
authors.forename: Vijaylaxmi
authors.initials: V
authors.lastname: Ray
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001778:Blood Coagulation Disorders / Q000175:diagnosis / Q000209:etiology / Q000628:therapy*; D001803:Blood Transfusion / Q000592:standards / Q000706:statistics & numerical data*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007194:India; D007223:Infant; D007297:Inpatients / Q000706:statistics & numerical data; D008297:Male; D008875:Middle Aged; D010976:Platelet Count; D017713:Platelet Transfusion / Q000592:standards / Q000706:statistics & numerical data; D012189:Retrospective Studies; D019595:Severe Dengue / Q000097:blood / Q000150:complications / Q000628:therapy*; D014600:Utilization Review