title: Evaluation of catheter-associated urinary tract infections and multi-drug-resistant Escherichia coli isolates from the urine of dogs with indwelling urinary catheters.
abstract: OBJECTIVE
  To determine the frequency of urinary tract infections (UTIs) in dogs with indwelling urinary catheters in an intensive care unit (ICU) and the frequency of multi-drug-resistant (MDR) Escherichia coli UTIs in those dogs.
  
  
  METHODS
  Prospective study.
  
  
  METHODS
  All dogs in the ICU with an indwelling urinary catheter from January 2003 through December 2003.
  
  
  METHODS
  Urine samples and rectal swab specimens were collected at admission and every 3 days until discharge from the hospital. Escherichia coli isolates from urine samples and rectal swab specimens and those from dogs that were temporally or spatially associated with dogs with MDR E coli UTIs underwent antimicrobial susceptibility testing. Pulsed-field gel electrophoresis was performed on MDR isolates from urine and rectal swab specimens.
  
  
  RESULTS
  Urinary catheters were placed in 137 dogs. Twenty-six UTIs were diagnosed, 15 on the day of admission and 11 after 3 or more days of catheterization. Of 12 dogs with E coli UTIs, 6 were infected at admission and 6 acquired the infection in the ICU. Two MDR E coli UTIs were detected, 1 of which was acquired in the ICU. One MDR E coli urinary isolate had an electrophoresis pattern similar to that of rectal isolates from the same dog. Urinary E coli isolates were most frequently resistant to ampicillin and cephalothin.
  
  
  CONCLUSIONS
  The ICU-acquired MDR E coli UTI likely originated from the dog's intestinal flora during hospitalization. Dogs that have been referred from a community practice may have MDR E coli UTIs at the time of admission.
authors.affiliation: Department of Clinical Studies, Ontario Veterinary College, University of Guelph, Guelph, ON N1G 2W1, Canada.
authors.forename: Jennifer
authors.initials: J
authors.lastname: Ogeer-Gyles
authors.forename: Karol
authors.initials: K
authors.lastname: Mathews
authors.forename: J Scott
authors.initials: JS
authors.lastname: Weese
authors.forename: John F
authors.initials: JF
authors.lastname: Prescott
authors.forename: Patrick
authors.initials: P
authors.lastname: Boerlin
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D002408:Catheters, Indwelling / Q000009:adverse effects*; D015169:Colony Count, Microbial; D003428:Cross Infection / Q000662:veterinary; D004283:Dog Diseases / Q000188:drug therapy / Q000209:etiology / Q000382:microbiology*; D004285:Dogs; D024881:Drug Resistance, Bacterial; D024901:Drug Resistance, Multiple, Bacterial; D004926:Escherichia coli / Q000187:drug effects*; D004927:Escherichia coli Infections / Q000188:drug therapy / Q000209:etiology / Q000382:microbiology / Q000662:veterinary*; D005260:Female; D006760:Hospitalization; D008297:Male; D008826:Microbial Sensitivity Tests / Q000662:veterinary; D011446:Prospective Studies; D012007:Rectum / Q000382:microbiology; D014552:Urinary Tract Infections / Q000188:drug therapy / Q000209:etiology / Q000382:microbiology / Q000662:veterinary*; D014556:Urine / Q000382:microbiology
chemical_list: D000900:Anti-Bacterial Agents