[Biological mechanisms of aging].
Contemporary views on the mechanisms of aging and aging variations--progeria and longevity are presented. Replicative aging, the roles of glycation and free radicals on the genetical determination of progeria and longevity are discussed.
Otová
B
B
Ustav biologie a lékarské genetiky 1 LF UK a VFN, Praha. boto@lf1.cuni.cz
Kalvach
Z
Z
Snejdrlová
M
M
D000375:Aging / Q000502:physiology*; D000975:Antioxidants / Q000378:metabolism; D017209:Apoptosis; D002118:Calcium / Q000378:metabolism; D002453:Cell Cycle; D002455:Cell Division; D005609:Free Radicals / Q000378:metabolism; D005947:Glucose / Q000378:metabolism; D006801:Humans; D015227:Lipid Peroxidation; D008136:Longevity / Q000235:genetics; D009154:Mutation; D011371:Progeria / Q000503:physiopathology; D016615:Telomere / Q000235:genetics
D000975:Antioxidants; D005609:Free Radicals; D005947:Glucose; D002118:Calcium