Pinch-off syndrome in patients with sickle cell disease receiving erythrocytapheresis.
A 6-year-old female with homozygous sickle cell disease had a central venous access device (CVAD) placed to facilitate chronic erythrocytapheresis. Erythrocytapheresis was ineffective due to the rare pinch-off syndrome causing communication between the dual lumen tubing. Awareness of and monitoring for the pinch-off syndrome is indicated in people with sickle cell disease and a CVAD for chronic erythrocytapheresis.
Nuss
Rachelle
R
Department of Pediatric Hematology, The Children's Hospital and the University of Colorado at Denver Health Sciences Center, Denver, Colorado, USA. nuss.rachelle@tchden.org
Cole
Laura
L
Le
Tuan
T
Orsini
Edmund
E
Harned
Roger
R
D000755:Anemia, Sickle Cell / Q000097:blood / Q000628:therapy*; D001781:Blood Component Removal; D002405:Catheterization, Central Venous; D002408:Catheters, Indwelling; D002648:Child; D017707:Erythrocyte Transfusion; D005260:Female; D006801:Humans; D013350:Subclavian Vein