title: Sample treatments prior to capillary electrophoresis-mass spectrometry.
abstract: Sample preparation is a crucial part of chemical analysis and in most cases can become the bottleneck of the whole analytical process. Its adequacy is a key factor in determining the success of the analysis and, therefore, careful selection and optimization of the parameters controlling sample treatment should be carried out. This work revises the different strategies that have been developed for sample preparation prior to capillary electrophoresis-mass spectrometry (CE-MS). Namely the present work presents an exhaustive and critical revision of the different samples treatments used together with on-line CE-MS including works published from January 2000 to July 2006.
authors.affiliation: Department of Analytical Chemistry, Nutrition and Food Science, University of La Laguna, Avda. Astrofísico Fco. Sánchez s/n, 38071 La Laguna, Tenerife, Spain. jhborges@ull.es
authors.forename: Javier
authors.initials: J
authors.lastname: Hernández-Borges
authors.forename: Teresa M
authors.initials: TM
authors.lastname: Borges-Miquel
authors.forename: Miguel Angel
authors.initials: MA
authors.lastname: Rodríguez-Delgado
authors.forename: Alejandro
authors.initials: A
authors.lastname: Cifuentes
mesh_terms: D053000:Analytic Sample Preparation Methods / Q000379:methods*; D019075:Electrophoresis, Capillary / Q000379:methods*; D013058:Mass Spectrometry / Q000379:methods*; D046210:Microfluidic Analytical Techniques; D011312:Pressure; D052616:Solid Phase Extraction; D052617:Solid Phase Microextraction