[Free radical oxidation in the assessment of health risk].
Aliovalent metals (d-metals, such as manganese, nickel, iron, copper, chromium, etc.) which are able to change the degree of oxidation, to activate free radical oxidative processes, and to initiate the development of the condition that is currently defined as oxidative stress soundly and which are diagnostic criteria in the prenosological assessment of health risks are prominent among other priority ambient air pollutants. The findings suggest that there is a direct relationship between the calculated indices characterizing the carcinogenic and noncarcinogenic effects, the risk of oxidative stress, the environmental availability of prooxidants, mainly d-elements (manganese, nickel, copper, zinc) and the actual values of an increase in the rate of lipid peroxidation, of a decrease in antioxidative activity, and of an elevation in the level of methemoglobin formation.
Boev
V M
VM
Krasikov
S I
SI
Svistunova
N V
NV
Neplokhov
A A
AA
Boev
M V
MV
Sharapova
N V
NV
Timoshinova
S V
SV
D000293:Adolescent; D000328:Adult; D018876:Environmental Illness / Q000209:etiology* / Q000378:metabolism; D004785:Environmental Pollutants / Q000009:adverse effects*; D016166:Free Radical Scavengers / Q000009:adverse effects; D006304:Health Status; D006801:Humans; D015227:Lipid Peroxidation / Q000187:drug effects*; D008875:Middle Aged; D018384:Oxidative Stress / Q000502:physiology*; D018570:Risk Assessment
D004785:Environmental Pollutants; D016166:Free Radical Scavengers