[Disturbances of the incretory and excretory pancreatic functions in patients suffering from psoriasis in combination with chronic opisthorchosis].
The aim of the study was to evaluate the incretory and excretory functions of the pancreas in patients suffering from psoriasis in combination with chronic opisthorchosis (CO). The subjects were 30 patients with psoriasis and CO, 20 patients with psoriasis without helminthiasis, 20 patients with CO, and 12 healthy individuals. The incretory pancreatic function was studied by measuring serum levels of pancreatic hormones (insulin, glucagon, and C-peptide) using radioimmunoassay with standard sets; the excretory function was studied by means of measuring serum levels of pancreatic enzymes (amylase and lipase) using a biochemical technique. Proteolytic capacity was evaluated using PABA test (per cent of the renal excretion of paraminobenzoic acid); amylolytic capacity was evaluated using coprogram results. The study revealed disturbances in the incretory and excretory functions of the pancreas in patients suffering from psoriasis or psoriasis with CO. The latter subgroup had more prominent disturbances.
Khardikova
S A
SA
Savkina
K A
KA
Kaliuzhina
M I
MI
D000328:Adult; D002908:Chronic Disease; D018450:Disease Progression; D005260:Female; D006801:Humans; D008099:Liver / Q000469:parasitology*; D008297:Male; D009889:Opisthorchiasis / Q000453:epidemiology* / Q000469:parasitology / Q000503:physiopathology*; D010195:Pancreatitis / Q000453:epidemiology* / Q000503:physiopathology*; D011565:Psoriasis / Q000453:epidemiology* / Q000503:physiopathology*