Palladium-catalyzed regiospecific aminocarbonylation of alkynes in the ionic liquid [bmim][Tf2N].
[Structure: see text] Regiospecific construction of 2-substituted acrylamides was achieved by palladium-catalyzed aminocarbonylation of alkynes in the ionic liquid [bmim][Tf2N] without any acid additive under relatively mild conditions. The ionic liquid was used as the reaction medium and also acted as a promoter. Acrylamides were obtained in moderate to excellent yields, and an important feature is that the catalyst system can be recycled five times without loss of catalytic activity.
Li
Yu
Y
Centre for Catalysis Research and Innovation, Department of Chemistry, University of Ottawa, 10 Marie Curie, Ottawa, Ontario, Canada K1N 6N5.
Alper
Howard
H
Yu
Zhengkun
Z