title: Systemic candidiasis in a dog, developing spondylitis.
abstract: A 4-year-old male Shiba dog initially presented with pain of an undetermined origin and hypersensitivity to touch. Seven days later, the dog developed ataxia, hind-leg weakness and knuckling. The dog died on 20 days after presentation. Postmortem examination revealed a mass in the body of thoracic vertebra. Histopathologically, the mass consisted of granulomatous inflammation, including fungal organisms that were immunohistochemically positive for Candida albicans. Similar granulomatous lesions were observed in the systemic lymph nodes, kidneys, pancreas, spleen, prostate gland, thyroid glands and heart. This case was diagnosed as systemic candidiasis with spondylitis.
authors.affiliation: Laboratory of Veterinary Pathology, Osaka Prefecture University, Osaka, Japan.
authors.forename: Mitsuru
authors.initials: M
authors.lastname: Kuwamura
authors.forename: Mika
authors.initials: M
authors.lastname: Ide
authors.forename: Jyoji
authors.initials: J
authors.lastname: Yamate
authors.forename: Yoshiko
authors.initials: Y
authors.lastname: Shiraishi
authors.forename: Takao
authors.initials: T
authors.lastname: Kotani
mesh_terms: D000818:Animals; D002176:Candida albicans / Q000254:growth & development*; D002177:Candidiasis / Q000382:microbiology / Q000473:pathology / Q000662:veterinary*; D004283:Dog Diseases / Q000382:microbiology* / Q000473:pathology; D004285:Dogs; D017809:Fatal Outcome; D008297:Male; D013166:Spondylitis / Q000382:microbiology / Q000473:pathology / Q000662:veterinary*; D013904:Thoracic Vertebrae / Q000382:microbiology / Q000473:pathology