title: False-positive xerostomia following radioactive iodine treatment: case report.
abstract: Radioactive iodine (131I), used in the treatment of differentiated thyroid carcinoma, is known to cause both short-term and long-term radiation damage to the salivary glands. The injury appears as glandular swellings and/or decreased salivation with 131I dosage and passage of time playing significant roles. A case report is presented to alert the profession to the existence of patients who have received 131I therapy and who complain shortly thereafter of xerostomia, but following a thorough examination are found to represent a group of false-positives. Emphasis is placed on the diagnostic techniques used in the differential diagnosis.
authors.affiliation: Division of Endocrinology, Diabetes, and Metabolism, University of Pennsylvania Medical School, Philadelphia, PA, USA.
authors.forename: Susan J
authors.initials: SJ
authors.lastname: Mandel
authors.forename: Louis
authors.initials: L
authors.lastname: Mandel
mesh_terms: D000328:Adult; D018687:Antidepressive Agents, Second-Generation / Q000009:adverse effects; D003937:Diagnosis, Differential; D005189:False Positive Reactions; D006801:Humans; D007457:Iodine Radioisotopes / Q000009:adverse effects*; D008297:Male; D010306:Parotid Gland / Q000528:radiation effects; D019275:Radiopharmaceuticals; D012793:Sialadenitis / Q000175:diagnosis; D013670:Sodium Pertechnetate Tc 99m; D013964:Thyroid Neoplasms / Q000532:radiotherapy; D014196:Trazodone / Q000009:adverse effects; D014987:Xerostomia / Q000175:diagnosis / Q000209:etiology*
chemical_list: D018687:Antidepressive Agents, Second-Generation; D007457:Iodine Radioisotopes; D019275:Radiopharmaceuticals; D013670:Sodium Pertechnetate Tc 99m; D014196:Trazodone