title: Desmoplastic giant congenital nevus with progressive depigmentation.
abstract: Desmoplastic hairless hypopigmented nevus is an extremely rare sclerotic, alopecic, and progressively hypopigmented giant congenital melanocytic nevus, which is histologically characterized by an intense desmoplasia. A significant trend toward spontaneous involution has been described. We report a case of desmoplastic hairless hypopigmented nevus that underwent a progressive depigmentation associated with loss of its woody consistency. The loss of induration appears to be the main marker for the complete regression of these nevi.
authors.affiliation: Department of Dermatology, Hospital Clínico Universitario, Valencia, Spain. jmMart@eresmas.com
authors.forename: José M
authors.initials: JM
authors.lastname: Martín
authors.forename: Esperanza
authors.initials: E
authors.lastname: Jordá
authors.forename: Carlos
authors.initials: C
authors.lastname: Monteagudo
authors.forename: Vicent
authors.initials: V
authors.lastname: Alonso
authors.forename: Guillermo
authors.initials: G
authors.lastname: Villalón
authors.forename: Dolores
authors.initials: D
authors.lastname: Ramón
mesh_terms: D018450:Disease Progression; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D009508:Nevus, Pigmented / Q000151:congenital* / Q000473:pathology* / Q000503:physiopathology; D010858:Pigmentation; D012445:Sacrococcygeal Region; D012878:Skin Neoplasms / Q000151:congenital* / Q000473:pathology* / Q000503:physiopathology