title: Catalytic asymmetric transfer hydrogenation of alpha-ketoesters with hantzsch esters.
abstract: C2-symmetric chiral copper(II)-bisoxazolines function as alcohol dehydrogenase mimics and catalyze highly enantioselective transfer hydrogenations of alpha-ketoesters with Hantzsch esters as a synthetic NADH analogue to give alpha-hydroxy esters in excellent enantioselectivities. [reaction: see text].
authors.affiliation: Max-Planck-Institut für Kohlenforschung, Kaiser-Wilhelm-Platz 1, 45470 Mülheim an der Ruhr, Germany.
authors.forename: Jung Woon
authors.initials: JW
authors.lastname: Yang
authors.forename: Benjamin
authors.initials: B
authors.lastname: List
mesh_terms: D000426:Alcohol Dehydrogenase / Q000737:chemistry; D002384:Catalysis; D003300:Copper / Q000737:chemistry; D004952:Esters / Q000737:chemistry; D007659:Ketones / Q000138:chemical synthesis*; D018716:Molecular Mimicry; D009243:NAD / Q000031:analogs & derivatives / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D004952:Esters; D007659:Ketones; D009243:NAD; D003300:Copper; D000426:Alcohol Dehydrogenase