title: Functional capacity, skeletal muscle strength, and skeletal muscle volume in patients with myocardial infarction.
abstract: Previous studies have reported that skeletal muscle strength is closely related to exercise capacity in patients with myocardial infarction (MI). However, none of the previous studies have fully investigated the correlation between exercise capacity and the skeletal muscle volume (MV). Seventy patients with MI underwent symptom-limited cardiopulmonary exercise testing using a treadmill. The MV was evaluated by electrical impedance analysis and the maximal knee extension strength (Peak torque: PT) was measured by a Biodex. The subjects were divided into 2 groups according to the MV (group L, MV < 22 kg; group H, MV > or = 22 kg). The PT was positively and significantly correlated with the peak V(.)O(2) in both the L and H groups (r = 0.70 versus r = 0.71). The MV of the lower limbs was positively correlated with the peak V(.)O(2) in the L group (r = 0.57), but not in the H group. The lower limb MV was positively and significantly correlated with PT in the L group (r = 0.48), but not in the H group. The exercise capacity of patients with MI is thought to depend on both the strength and volume of the skeletal muscle. In MI patients with high muscle volume, exercise capacity was determined by skeletal muscle strength alone.
authors.affiliation: Division of Cardiology, Department of Internal Medicine, St. Marianna University School of Medicine, Kanagawa, Japan.
authors.forename: Keisuke
authors.initials: K
authors.lastname: Kida
authors.forename: Naohiko
authors.initials: N
authors.lastname: Osada
authors.forename: Yoshihiro J
authors.initials: YJ
authors.lastname: Akashi
authors.forename: Hiromitsu
authors.initials: H
authors.lastname: Sekizuka
authors.forename: Masaki
authors.initials: M
authors.lastname: Izumo
authors.forename: Yuki
authors.initials: Y
authors.lastname: Ishibashi
authors.forename: Takashi
authors.initials: T
authors.lastname: Shimozato
authors.forename: Akio
authors.initials: A
authors.lastname: Hayashi
authors.forename: Kihei
authors.initials: K
authors.lastname: Yoneyama
authors.forename: Eiji
authors.initials: E
authors.lastname: Takahashi
authors.forename: Kengo
authors.initials: K
authors.lastname: Suzuki
authors.forename: Masachika
authors.initials: M
authors.lastname: Tamura
authors.forename: Koji
authors.initials: K
authors.lastname: Inoue
authors.forename: Kazuto
authors.initials: K
authors.lastname: Omiya
authors.forename: Fumihiko
authors.initials: F
authors.lastname: Miyake
mesh_terms: D017097:Electric Impedance; D005080:Exercise Test; D017079:Exercise Tolerance / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D053580:Muscle Strength / Q000502:physiology*; D018482:Muscle, Skeletal / Q000033:anatomy & histology* / Q000502:physiology*; D009203:Myocardial Infarction / Q000503:physiopathology*; D009929:Organ Size