Ophthalmodynamometric differences between ischemic vs nonischemic retinal vein occlusion.
OBJECTIVE
To estimate the central retinal vein pressure in patients with ischemic vs nonischemic central retinal vein occlusion (CRVO).


METHODS
Prospective clinical observational comparative study.


METHODS
The study included 28 patients with CRVO, either of the ischemic type (n = 7) or the nonischemic type (n = 21). The control group consisted of 38 subjects without retinal disease. A new ophthalmodynamometer consisting of a Goldmann contact lens fitted with a pressure sensor into the holding grip of the contact lens, was used to indirectly estimate the central retinal artery and vein pressure.


RESULTS
Central retinal vein pressure was significantly higher in the ischemic CRVO group than in the nonischemic CRVO group (91.5 +/- 30.1 arbitrary units vs 52.4 +/- 32.5 arbitrary units; P = .014), in which it was significantly (P < .001) higher than in the control group (4.8 +/- 8.1 arbitrary units). Central retinal vein pressure was higher than the diastolic central retinal artery pressure significantly (P = .039) more frequently in the ischemic CRVO group (7/7 or 100%) than in the nonischemic CRVO group (8/21 or 38%) or the control group (0/38; P < .001). Central retinal artery pressure was significantly (P = .017) lower in the ischemic CRVO group (46.0 +/- 10.6 arbitrary units) than in the nonischemic CRVO group (64.5 +/- 22.8 arbitrary units), in which it was significantly (P = .016) lower than in the control group (79.9 +/- 22.3 arbitrary units).


CONCLUSIONS
Ophthalmodynamometric estimation of the retinal vein pressure may be helpful for the differentiation between the ischemic vs nonischemic type of CRVO. In the ischemic type, vein pulsations were usually observed at supradiastolic arterial values.
Jonas
Jost B
JB
Department of Ophthalmology, Faculty of Clinical Medicine Mannheim, Ruprecht-Karls-University of Heidelberg, Theodor-Kutzer-Ufer 1-3, 68167 Mannheim, Germany. Jost.Jonas@augen.ma.uni-heidelberg.de
Harder
Bjoern
B
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D007511:Ischemia / Q000175:diagnosis* / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D009884:Ophthalmodynamometry / Q000379:methods*; D009898:Optic Disk / Q000098:blood supply; D011446:Prospective Studies; D012169:Retinal Vein / Q000473:pathology*; D012170:Retinal Vein Occlusion / Q000175:diagnosis* / Q000503:physiopathology; D014690:Venous Pressure / Q000502:physiology