Exploitation of cyclopropane ring-cleavage reactions for the rapid assembly of tetracyclic frameworks related to gibberellins.
[Structure: see text] The readily available hexahydrofluorene 5 has been elaborated over six steps, including three involving cyclopropane ring-cleavage reactions, into compound 12 which incorporates the carbocyclic framework associated with gibberellins.
Banwell
Martin G
MG
Research School of Chemistry, Institute of Advanced Studies, The Australian National University, Canberra, ACT 0200, Australia. mgb@rsc.anu.edu.au
Phillis
Andrew T
AT
Willis
Anthony C
AC