Development of a Friedel-Crafts triflation.
The development of a new variant of the Friedel-Crafts reaction that yields 3-aryl enol triflates is described. The reaction is practical, is atom-economical, and works well with electron-rich arene substrates. [reaction: see text].
Grundl
Marc A
MA
Department of Chemistry, University of California, Berkeley, Berkeley, California 94720-1460, USA.
Kaster
Anne
A
Beaulieu
Ellen D
ED
Trauner
Dirk
D
D000478:Alkylation; D000812:Anhydrides; D007202:Indicators and Reagents; D009682:Magnetic Resonance Spectroscopy; D008698:Mesylates / Q000138:chemical synthesis*; D012997:Solvents
D000812:Anhydrides; D007202:Indicators and Reagents; D008698:Mesylates; D012997:Solvents