title: Impact of StatLock securing device on symptomatic catheter-related urinary tract infection: a prospective, randomized, multicenter clinical trial.
abstract: BACKGROUND
  The objective of this study was to assess the impact of using the StatLock securing device on symptomatic catheter-related urinary tract infection (UTI).
  
  
  METHODS
  In this prospective, randomized, multicenter clinical trial, adult patients with spinal cord injury or dysfunction because of multiple sclerosis were randomized to have their indwelling bladder catheters secured in place by using the StatLock device (experimental group) versus preexisting methods (control group that included tape, Velcro strap, CathSecure, or none). Patients were monitored for the development of symptomatic UTI within the subsequent period of 8 weeks.
  
  
  RESULTS
  Of a total of 127 enrolled patients, 118 (60 in the experimental group and 58 in the control group) were evaluable. The 2 groups of evaluable patients were comparable in terms of clinical characteristics and risk factors for infection. Symptomatic UTI was diagnosed in 8 of 60 (13.3%) patients in the experimental group versus 14 of 58 (24.1%) patients in the control group (P = .16; RR = 0.55, 95% confidence interval: 0.25-1.22).
  
  
  CONCLUSIONS
  Although the trial size precluded the demonstration of statistically significant differences, the finding of a 45% reduction in the rate of symptomatic UTI in patients who received the StatLock securing device is clinically relevant and prompts further investigations.
authors.affiliation: Michael E. Debakey Veterans Affairs Medical Center, Houston, TX, USA. rdarouiche@aol.com
authors.forename: Rabih O
authors.initials: RO
authors.lastname: Darouiche
authors.forename: Lance
authors.initials: L
authors.lastname: Goetz
authors.forename: Teresa
authors.initials: T
authors.lastname: Kaldis
authors.forename: Colleen
authors.initials: C
authors.lastname: Cerra-Stewart
authors.forename: Atef
authors.initials: A
authors.lastname: AlSharif
authors.forename: Michael
authors.initials: M
authors.lastname: Priebe
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002408:Catheters, Indwelling / Q000382:microbiology*; D004867:Equipment Design / Q000295:instrumentation*; D005260:Female; D006801:Humans; D017053:Infection Control / Q000295:instrumentation*; D008297:Male; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000150:complications; D012307:Risk Factors; D013119:Spinal Cord Injuries / Q000150:complications; D016896:Treatment Outcome; D014546:Urinary Catheterization / Q000009:adverse effects / Q000379:methods*; D014552:Urinary Tract Infections / Q000517:prevention & control*