Tricholemmoma of the nose.
OBJECTIVE
The objectives of this case report are to (1) identify clinical presentations of tricholemmoma, (2) discuss the characteristics of Cowden syndrome and the relationship between this syndrome and tricholemmoma, and (3) differentiate tricholemmoma from other superficial cutaneous tumors such as basal cell carcinoma and granulomas.


METHODS
We present a literature review and a case report.


METHODS
A literature review of tricholemmoma and a case report of an unusual manifestation of this neoplasm were presented.


RESULTS
Tricholemmoma was first described as a cutaneous neoplasm in 1962. It is associated with the Cowden syndrome and can be misdiagnosed as a more aggressive cutaneous malignancy. We report an unusual case of tricholemmoma presenting as a nasal mass.


CONCLUSIONS
Tricholemmoma is described as having a predilection for the head and neck, yet little information has been published about this disorder within the Otolaryngology literature. Otolaryngologist-head and neck surgeons must be familiar with this neoplasm because it can be frequently misdiagnosed as an aggressive cutaneous malignancy and hence can be incorrectly treated. We describe the presentation and diagnosis of tricholemmoma, describe the frequent association of this neoplasm with Cowden syndrome, and report an unusual presentation of tricholemmoma as an intranasal mass.
Spiegel
Jeffrey H
JH
Department of Otolaryngology-Head and Neck Surgery, Boston University School of Medicine, Boston, MA 02118, USA. jeffrey.spiegel@bmc.org
Khodai
Naghmeh
N
D002280:Basal Cell Carcinoma / Q000175:diagnosis / Q000473:pathology; D003937:Diagnosis, Differential; D005500:Follow-Up Studies; D006099:Granuloma / Q000175:diagnosis / Q000473:pathology; D006223:Hamartoma Syndrome, Multiple / Q000175:diagnosis / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009669:Nose Neoplasms / Q000175:diagnosis* / Q000473:pathology; D012878:Skin Neoplasms / Q000175:diagnosis* / Q000473:pathology