title: MACiE (Mechanism, Annotation and Classification in Enzymes): novel tools for searching catalytic mechanisms.
abstract: MACiE (Mechanism, Annotation and Classification in Enzymes) is a database of enzyme reaction mechanisms, and is publicly available as a web-based data resource. This paper presents the first release of a web-based search tool to explore enzyme reaction mechanisms in MACiE. We also present Version 2 of MACiE, which doubles the dataset available (from Version 1). MACiE can be accessed from http://www.ebi.ac.uk/thornton-srv/databases/MACiE/
authors.affiliation: EMBL-EBI, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK. gemma@ebi.ac.uk
authors.forename: Gemma L
authors.initials: GL
authors.lastname: Holliday
authors.forename: Daniel E
authors.initials: DE
authors.lastname: Almonacid
authors.forename: Gail J
authors.initials: GJ
authors.lastname: Bartlett
authors.forename: Noel M
authors.initials: NM
authors.lastname: O'Boyle
authors.forename: James W
authors.initials: JW
authors.lastname: Torrance
authors.forename: Peter
authors.initials: P
authors.lastname: Murray-Rust
authors.forename: John B O
authors.initials: JB
authors.lastname: Mitchell
authors.forename: Janet M
authors.initials: JM
authors.lastname: Thornton
mesh_terms: D002384:Catalysis; D030562:Databases, Protein; D004798:Enzymes / Q000737:chemistry* / Q000145:classification / Q000378:metabolism; D020407:Internet; D011487:Protein Conformation; D017386:Sequence Homology, Amino Acid; D012984:Software; D014584:User-Computer Interface
chemical_list: D004798:Enzymes