Neurological sequelae of intrauterine warfarin exposure.
Warfarin embryopathy is a well-defined manifestation of intrauterine warfarin exposure. The embryopathy phenotype as it relates to the nervous system is broad and poorly recognised. We describe an adult with neurological sequelae of fetal warfarin exposure. We review previous cases with neurological sequelae and discuss the pathogenetic mechanism in light of recent research.
Raghav
Sanjay
S
Department of Neurology, Monash Medical Centre, 246 Clayton Road, Clayton, Victoria 3168, Australia.
Reutens
David
D
D000014:Abnormalities, Drug-Induced / Q000209:etiology*; D000328:Adult; D000925:Anticoagulants / Q000009:adverse effects*; D003072:Cognition Disorders / Q000139:chemically induced; D003638:Deafness / Q000139:chemically induced*; D006801:Humans; D008297:Male; D009295:Nasal Bone / Q000002:abnormalities*; D013118:Spinal Cord Diseases / Q000139:chemically induced*; D013131:Spine / Q000002:abnormalities; D014859:Warfarin / Q000009:adverse effects*
D000925:Anticoagulants; D014859:Warfarin