[Neurotoxicity related to lithium-risperidon combination treatment in a patient with schizoaffective disorder].
OBJECTIVE
The case of a schizoaffective patient with a neurotoxic encephalopathy related to lithium-risperidon combination treatment is explored.


METHODS
A case report and the relevant theoretical and clinical deliberations are described.


CONCLUSIONS
Neurotoxicity related to lithium-risperidon combination treatment is the result of an interaction of different ethiopathogenetic mechanisms. The EEG is the most important diagnostic parameter.
Böker
Heinz
H
Psychiatrische Universitätsklinik Zürich, Zürich, Switzerland. boeker@bli.unizh.ch
Brandenberger
Mathias
M
Schopper
Christian
C
D018692:Antimanic Agents / Q000008:administration & dosage / Q000633:toxicity*; D014150:Antipsychotic Agents / Q000008:administration & dosage / Q000633:toxicity*; D003072:Cognition Disorders / Q000139:chemically induced / Q000175:diagnosis; D004347:Drug Interactions; D004359:Drug Therapy, Combination; D004409:Dyskinesia, Drug-Induced / Q000175:diagnosis*; D004569:Electroencephalography / Q000187:drug effects; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008875:Middle Aged; D009459:Neuroleptic Malignant Syndrome / Q000175:diagnosis*; D009460:Neurologic Examination / Q000187:drug effects; D020258:Neurotoxicity Syndromes / Q000175:diagnosis*; D011618:Psychotic Disorders / Q000188:drug therapy*; D018967:Risperidone / Q000008:administration & dosage / Q000633:toxicity*
D018692:Antimanic Agents; D014150:Antipsychotic Agents; D018967:Risperidone