title: Cyclization reactions of homopropargyl azide derivatives catalyzed by PtCl4 in ethanol solution: synthesis of functionalized pyrrole derivatives.
abstract: [Structure: see text] PtCl4-catalyzed cyclization reactions of homopropargyl azide derivatives to pyrrole rings were investigated. Using ethanol as solvent with 2,6-di-tert-butyl-4-methylpyridine as the base was found to be the best set of conditions for effecting this ring-closing reaction. These reaction conditions can be applied to the preparation of functionalized pyrrole derivatives, with no effect on the functional groups.
authors.affiliation: Graduate School of Pharmaceutical Sciences, Tohoku University, Aoba-ku, Sendai 980-8578, Japan. hiroya@mail.tains.tohoku.ac.jp
authors.forename: Kou
authors.initials: K
authors.lastname: Hiroya
authors.forename: Shigemitsu
authors.initials: S
authors.lastname: Matsumoto
authors.forename: Masayasu
authors.initials: M
authors.lastname: Ashikawa
authors.forename: Kentaro
authors.initials: K
authors.lastname: Ogiwara
authors.forename: Takao
authors.initials: T
authors.lastname: Sakamoto
mesh_terms: D001386:Azides / Q000737:chemistry*; D002384:Catalysis; D003500:Cyclization; D000431:Ethanol / Q000737:chemistry*; D015394:Molecular Structure; D017671:Platinum Compounds / Q000737:chemistry*; D011758:Pyrroles / Q000737:chemistry*
chemical_list: D001386:Azides; D017671:Platinum Compounds; D011758:Pyrroles; D000431:Ethanol; C032741:platinum tetrachloride