[Comparative characteristic of Mycobacterium tuberculosis strain drug sensitivity].
The medicinal sensitivity of tuberculosis mycobacteria strains of the patients with pulmonary and extrapulmonary tuberculosis was studied in completely automated system Bactec MGIT. A comparison was also made with the research results of medicinal sensitivity by the method of absolute concentrations on Levenstein-Jensen hard nutrient medium. A considerable coincidence in results of these two methods: a percentag of analogous results of the test of sensitivity of MBT to ABS in Bactec MGIT 960 system and by the method of absolute concentrations for riphampicyn and izoniazyde was 97.2%, for streptomycin - 94.4%. Besides, the term of obtaining the results in Bactec MGIT 960 automated system is 5 to 13 days, while with the absolute concentrations method the term of obtaining the results is 21 to 26 days. This plays an important role in prescribing the proper antituberculous therapy scheme.
Kondratiuk
N V
NV
Sybirnyĭ
A V
AV
Sybirna
R I
RI
D000995:Antitubercular Agents / Q000494:pharmacology*; D015373:Bacterial Typing Techniques; D006801:Humans; D008826:Microbial Sensitivity Tests; D009169:Mycobacterium tuberculosis / Q000187:drug effects / Q000254:growth & development / Q000302:isolation & purification; D014394:Tuberculosis, Osteoarticular / Q000382:microbiology; D014397:Tuberculosis, Pulmonary / Q000382:microbiology
D000995:Antitubercular Agents