title: Synthesis of benzonorcaradienes by gold(I)-catalyzed [4+3] annulation.
abstract: A formal [4 + 3]-annulation of vinyl arenes and diynyl propargyl esters is described. A mechanism involving cationic phosphinegold(I)-catalyzed tandem cyclopropanation/hydroarylation to produce the benzonorcaradiene products is proposed. In accord with this mechanism, the alkynyl cyclopropane can also be prepared with excellent regio- and diastereocontrol.
authors.affiliation: Department of Chemistry, University of California, Berkeley, California 94720, USA.
authors.forename: David J
authors.initials: DJ
authors.lastname: Gorin
authors.forename: Pascal
authors.initials: P
authors.lastname: Dubé
authors.forename: F Dean
authors.initials: FD
authors.lastname: Toste
mesh_terms: D001555:Benzene Derivatives / Q000138:chemical synthesis*; D002384:Catalysis; D006046:Gold / Q000737:chemistry*
chemical_list: D001555:Benzene Derivatives; D006046:Gold