A new local ablation for solid malignant tumours: anti-tumour effect of hyperthermal and electrochemical therapy on transplantable mouse cancer.
OBJECTIVE
Hyperthermia induced by electrothermal needle (ETN) and electrochemical therapy (ECT) were combined (HECT) and the anti-tumor effect was evaluated.


METHODS
Mice with Sarcoma180 were randomized into four different treatment groups: Control, ECT alone, Hyperthermia alone and HECT.


RESULTS
The tumours in the HECT group were completely destroyed and they did not recur within a period of 10 days after treatment. However, tumour recurrence was found in six mice in the Hyperthermia group and five mice in the ECT group.


CONCLUSIONS
The HECT is a potentially effective way to treat solid malignant tumours.
Xie
Lei
L
Department of Head and Neck Surgery, Sir Run Run Shaw Hospital, Hangzhou, Zhejiang, PR China.
Sun
Caijun
C