Straightforward and highly efficient catalyst-free one-pot synthesis of dithiocarbamates under solvent-free conditions.
[Structure: see text] A highly efficient and simple synthesis of dithiocarbamates is possible based on the one-pot reaction of amines, CS2, and alkyl halides without using a catalyst under solvent-free conditions. The mild reaction conditions, high yields, and broad scope of the reaction illustrate the good synthetic utility of this method. The reaction is a highly atom-economic process for production of S-alkyl thiocarbamates and successfully can be used in high quantities in the pharmaceutical or agrochemical industries.
Azizi
Najmedin
N
Department of Chemistry, Sharif University of Technology, P. O. Box 11465-9516, Tehran 11365, Iran.
Aryanasab
Fezzeh
F
Saidi
Mohammad R
MR
D002384:Catalysis; D015394:Molecular Structure; D013859:Thiocarbamates / Q000138:chemical synthesis*
D013859:Thiocarbamates