I2 imaging: cancer biology and the tumor microenvironment.
The use of imaging techniques to understand the role of the tumor microenvironment in cancer progression was the topic of a National Cancer Institute (NCI)-sponsored think tank entitled "I2 Imaging: Cancer Biology and the Tumor Microenvironment," held in Alexandria, Virginia on June 8 to 10, 2006. Participants discussed both recent progress in the use of imaging to dissect cellular and molecular interactions within the tumor microenvironment and the challenges that remain. Recommendations made to the NCI included (a) holding an annual meeting at which biologists, clinicians, and imaging scientists could exchange data, facilitating new collaborations within this multidisciplinary field; (b) funding both research and training specifically designed to foster a cross-disciplinary focus; (c) creating and making available a variety of resources to interested investigators, such as a repository of stromal cells and extracellular matrix molecules; and (d) taking steps to encourage translation of the basic research findings into the clinic.
Sloane
Bonnie F
BF
Department of Pharmacology, Karmanos Cancer Institute, Wayne State University School of Medicine, Detroit, Michigan 48201, USA. bsloane@med.wayne.edu
Gillies
Robert J
RJ
Mohla
Suresh
S
Sogn
John A
JA
Menkens
Anne E
AE
Sullivan
Daniel C
DC
D035843:Biomedical Research / Q000379:methods / Q000639:trends; D003952:Diagnostic Imaging / Q000379:methods*; D006801:Humans; D009369:Neoplasms / Q000378:metabolism* / Q000473:pathology*