First enantioselective organocatalytic allylation of simple aldimines with allyltrichlorosilane.
A new organocatalytic system, novel chiral bisformamide and in situ generated L-proline-derived allylsilane reagent , which converts different aldimines to homoallylic amines in good to high yields (up to 95%) and good enantioselectivities (up to 85% ee) has been described.
Jagtap
Sunil B
SB
Institut für Organische und Biomolekulare Chemie der Georg-August-Universität Göttingen, Tammannstrasse 2, 37077, Göttingen, Germany.
Tsogoeva
Svetlana B
SB
D000475:Alkenes / Q000737:chemistry*; D000627:Aminophenols / Q000737:chemistry; D002384:Catalysis; D005559:Formamides / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D015394:Molecular Structure; D012821:Silanes / Q000737:chemistry*; D013237:Stereoisomerism
D000475:Alkenes; D000627:Aminophenols; D005559:Formamides; D012821:Silanes; C516132:allyltrichlorosilane