title: [Development of thrombi on an Amplatzer PFO Occluder].
abstract: In a 37-year-old female with previous paradoxical embolism and an identified PFO, a transcatheter closure of the defect was performed with an Amplatzer PFO Occluder. The patient suffered additional embolic episodes, and three months after the implantation, echocardiography showed several thrombi attached to the right side of the occluder, despite continuous administration of aspirin and the absence of significant coagulation disorders. The PFO may have been an innocent bystander, and the thrombogenic potential of the device and the optimal antithrombotic treatment need further investigation.
authors.affiliation: Arhus Universitetshospital, Skejby Sygehus, Hjertemedicinsk Afdeling B. birgittenielsen@dadlnet.dk
authors.forename: Birgitte
authors.initials: B
authors.lastname: Nielsen
authors.forename: Ole
authors.initials: O
authors.lastname: May
authors.forename: Henning
authors.initials: H
authors.lastname: Mølgaard
mesh_terms: D000328:Adult; D000925:Anticoagulants / Q000627:therapeutic use; D006328:Cardiac Catheterization; D006348:Cardiac Surgical Procedures / Q000009:adverse effects* / Q000295:instrumentation; D004621:Embolization, Therapeutic / Q000009:adverse effects* / Q000295:instrumentation; D005260:Female; D006344:Heart Septal Defects, Atrial / Q000601:surgery*; D006801:Humans; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use; D011183:Postoperative Complications / Q000188:drug therapy / Q000209:etiology* / Q000517:prevention & control; D013927:Thrombosis / Q000188:drug therapy / Q000209:etiology* / Q000517:prevention & control
chemical_list: D000925:Anticoagulants; D010975:Platelet Aggregation Inhibitors