Interpretation of serologic tests in an HIV-infected patient with kidney disease.
BACKGROUND
A 32-year-old African American man with HIV infection presented with hemoptysis, shortness of breath and renal insufficiency. Serologic testing revealed the presence of anti-glomerular basement membrane antibodies and equivocal levels of anti-myeloperoxidase antibodies.


METHODS
Physical examination, urine and blood analysis, kidney ultrasound, chest radiograph, sputum cultures, bronchoscopy and renal biopsy.


METHODS
Reactivation of tuberculosis infection, immune complex glomerulonephritis, and 'false-positive' anti-glomerular basement membrane and anti-myeloperoxidase antibodies.


RESULTS
Directly observed therapy with four-drug anti-tuberculosis therapy and conservative management of chronic kidney disease.
Hernandez
German T
GT
Texas Tech Health Sciences Center at El Paso, Department of Internal Medicine, 4800 Alberta Avenue, El Paso, TX 79905, USA. german.hernandez@ttuhsc.edu
Critchfield
Jeffrey M
JM
Rodriguez
Rudolph A
RA
D000328:Adult; D015658:HIV Infections / Q000150:complications*; D006801:Humans; D007674:Kidney Diseases / Q000097:blood* / Q000175:diagnosis* / Q000209:etiology; D008297:Male; D012698:Serologic Tests