title: Severe acute pancreatitis caused by organophosphate poisoning.
abstract: Organophosphate intoxication may be caused pancreatitis, but the role of diagnostic imaging for pancreatitis in these patients has not been well defined. We recently encountered a patient with organophosphate poisoning showing hyperamylasemia who was proven to have severe acute pancreatitis by CT findings. The patient was a 69-year-old woman who presented to a local hospital with disturbance of consciousness. She was initially treated for cerebral infarction, but an extremely low level of ChE was noted on Day 3. The patient was then referred to our institution. Examination of the abdomen revealed weak intestinal peristalsis, blood chemistry showed an increased level of serum amylase, and the urinary organophosphate test was positive. Based on the findings obtained by abdominal CT scanning, severe acute pancreatitis was diagnosed. Clouding of her consciousness resolved on day 21, but a pancreatic pseudocyst was detected on day 41.
authors.affiliation: Department of Emergency and Critical Care Medicine, Kinki University School of Medicine.
authors.forename: Mitsuhide
authors.initials: M
authors.lastname: Hamaguchi
authors.forename: Akira
authors.initials: A
authors.lastname: Namera
authors.forename: Noriko
authors.initials: N
authors.lastname: Tsuda
authors.forename: Toshifumi
authors.initials: T
authors.lastname: Uejima
authors.forename: Katsuyuki
authors.initials: K
authors.lastname: Maruyama
authors.forename: Tohoru
authors.initials: T
authors.lastname: Kanai
authors.forename: Ikuhiro
authors.initials: I
authors.lastname: Sakata
mesh_terms: D000208:Acute Disease; D005260:Female; D006801:Humans; D008875:Middle Aged; D062025:Organophosphate Poisoning; D010192:Pancreatic Pseudocyst / Q000175:diagnosis / Q000209:etiology; D010195:Pancreatitis / Q000175:diagnosis / Q000209:etiology*; D010575:Pesticides / Q000506:poisoning*; D012720:Severity of Illness Index; D014057:Tomography, X-Ray Computed
chemical_list: D010575:Pesticides