title: Pro: Aprotinin has a good efficacy and safety profile relative to other alternatives for prevention of bleeding in cardiac surgery.
authors.forename: Simon C
authors.initials: SC
authors.lastname: Body
authors.forename: C David
authors.initials: CD
authors.lastname: Mazer
mesh_terms: D015119:Aminocaproic Acid / Q000627:therapeutic use; D000818:Animals; D007611:Aprotinin / Q000009:adverse effects / Q000627:therapeutic use*; D016063:Blood Loss, Surgical / Q000517:prevention & control*; D006348:Cardiac Surgical Procedures; D004342:Drug Hypersensitivity / Q000453:epidemiology; D006490:Hemostatics / Q000627:therapeutic use*; D006801:Humans; D015201:Meta-Analysis as Topic; D016032:Randomized Controlled Trials as Topic; D051437:Renal Insufficiency / Q000209:etiology; D013927:Thrombosis / Q000209:etiology; D014148:Tranexamic Acid / Q000627:therapeutic use; D016896:Treatment Outcome
chemical_list: D006490:Hemostatics; D014148:Tranexamic Acid; D007611:Aprotinin; D015119:Aminocaproic Acid