title: A clinical survival score predicts the likelihood to benefit from preoperative thallium scanning and coronary revascularization before major vascular surgery.
abstract: OBJECTIVE
  Guidelines advocate selective non-invasive testing before major non-cardiac surgery, yet data defining who may benefit from such tests is lacking. We aimed to find the predictors that define patients who are most likely to benefit from preoperative cardiac testing and coronary revascularization (CR).
  
  
  RESULTS
  In 624 consecutive major vascular surgery patients, the preoperative thallium scanning (PTS) results and subsequent CRs were correlated with long-term (3-15 years) survival. Of all patients, 510 (80.6%) had PTS, 154 (24.7%) had moderate-severe ischaemia on PTS, and 96 (15.4%) underwent CR. Seven predictors: age >or=65, diabetes, cerebrovascular disease, ischaemic heart disease, congestive heart failure, ST-depression on preoperative ECG, and renal insufficiency, independently determined long-term survival. A long-term survival score (LTSS) comprised of these predictors, divided all patients into low, intermediate, and high-risk groups (0-1, 2-3, >or=4 predictors, respectively) with a 5-year survival of 83 +/- 2%, 60 +/- 3%, and 34 +/- 6%, respectively. Compared with low-risk patients, intermediate and high-risk patients had worse survival [HR (CI) = 2.6 (2.0-3.4) and 5.9 (4.1-8.9), respectively, P < 0.001]. Yet, only the intermediate-risk group had better long-term survival following preoperative CR [HR = 0.48 (0.31-0.75), P = 0.001]. The low-risk groups' favourable survival and high-risk groups' poor survival were not significantly affected by CR.
  
  
  CONCLUSIONS
  Intermediate-risk patients (LTSS 2-3) are most likely to have a long-term survival benefit from PTS and CR.
authors.affiliation: Department of Anaesthesiology, Hebrew University, Hadassah Medical Center, Jerusalem 91120, Israel. gio@cc.huji.ac.il
authors.forename: Giora
authors.initials: G
authors.lastname: Landesberg
authors.forename: Yacov
authors.initials: Y
authors.lastname: Berlatzky
authors.forename: Moshe
authors.initials: M
authors.lastname: Bocher
authors.forename: Ron
authors.initials: R
authors.lastname: Alcalai
authors.forename: Haim
authors.initials: H
authors.lastname: Anner
authors.forename: Tatyana
authors.initials: T
authors.lastname: Ganon-Rozental
authors.forename: Myron H
authors.initials: MH
authors.lastname: Luria
authors.forename: Inna
authors.initials: I
authors.lastname: Akopnik
authors.forename: Charles
authors.initials: C
authors.lastname: Weissman
authors.forename: Morris
authors.initials: M
authors.lastname: Mosseri
mesh_terms: D000368:Aged; D015906:Angioplasty, Balloon, Coronary / Q000379:methods; D005260:Female; D006801:Humans; D007902:Length of Stay; D008297:Male; D017202:Myocardial Ischemia / Q000000981:diagnostic imaging / Q000401:mortality / Q000517:prevention & control*; D009204:Myocardial Revascularization / Q000379:methods* / Q000401:mortality; D011183:Postoperative Complications / Q000401:mortality / Q000517:prevention & control*; D011300:Preoperative Care / Q000379:methods* / Q000401:mortality; D012189:Retrospective Studies; D018570:Risk Assessment; D015607:Stents; D016019:Survival Analysis; D013794:Thallium Radioisotopes; D015899:Tomography, Emission-Computed, Single-Photon / Q000379:methods; D014652:Vascular Diseases / Q000000981:diagnostic imaging / Q000401:mortality / Q000601:surgery*
chemical_list: D013794:Thallium Radioisotopes