title: [Does interventional therapy prolong the patency of hemodialysis fistulas and grafts?].
abstract: OBJECTIVE
  To retrospectively evaluate procedural success and patency after endovascular treatment of acute dysfunctional hemodialysis fistulas and grafts in a non-preselected patient cohort.
  
  
  METHODS
  185 angiographies of hemodialysis fistulas and grafts on the upper extremities were analyzed for 120 patients (53 male, 67 female; mean-age 63.1 +/- 11.4, range 24 - 91). 70 % (n = 130) were native arteriovenous fistulas, 17 % (n = 31) were prosthetic grafts, and 13 % (n = 24) were non-specific. In total, 278 lesions requiring endovascular treatment were detected. 13 % (n = 35) of the lesions were located in the arterial inflow, 18 % (n = 49) in native arteriovenous anastomoses, 7 % (n = 19) in prosthetic grafts and 62 % (n = 171) in the venous outflow. The primary, secondary and cumulative patency after endovascular treatment was calculated.
  
  
  RESULTS
  In 51 % (n = 94) of the cases endovascular treatment could be performed, in 8 % (n = 14) no lesion requiring treatment was detected, and in 42 % (n = 77) intervention was not considered possible. In 45 % (n = 124) of the detected lesions endovascular treatment was successful, in 18 % (n = 51) the intervention failed, and in 37 % (n = 103) intervention was not considered possible. The complication rate was 5 % (n = 10). The primary, secondary, and cumulative patency rates for 50 % of the hemodialysis fistulas and grafts after endovascular treatment were 65, 191, and 370 days, respectively. The results differed significantly from each other with p < 0.05 in the log rank test and log rank trend test.
  
  
  CONCLUSIONS
  Endovascular treatment of acute dysfunctional hemodialysis fistulas and grafts is effective in restoring the patency for hemodialysis.
authors.affiliation: Abteilung Radiologie, Universitätsklinikum Schleswig Holstein, Campus Kiel. jostphilipp@web.de
authors.forename: P J
authors.initials: PJ
authors.lastname: Schaefer
authors.forename: S
authors.initials: S
authors.lastname: Müller-Hülsbeck
authors.forename: F K
authors.initials: FK
authors.lastname: Schaefer
authors.forename: J
authors.initials: J
authors.lastname: Soehne
authors.forename: N
authors.initials: N
authors.lastname: Charalambous
authors.forename: M
authors.initials: M
authors.lastname: Heller
authors.forename: T
authors.initials: T
authors.lastname: Jahnke
mesh_terms: D000208:Acute Disease; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000792:Angiography; D000800:Angioplasty, Balloon; D001166:Arteriovenous Shunt, Surgical; D001807:Blood Vessel Prosthesis; D015331:Cohort Studies; D005260:Female; D006083:Graft Occlusion, Vascular / Q000000981:diagnostic imaging / Q000628:therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000000981:diagnostic imaging; D011475:Prosthesis Failure; D006435:Renal Dialysis; D012189:Retrospective Studies; D014654:Vascular Patency / Q000502:physiology*