Nonenzymatic oligomerization of RNA by TNA templates.
Cytosine TNA promotes nonenzymatic, template-directed oligomerization of complementary activated rGMP, leading to selective and efficient formation of RNA products. This process models "genetic takeover" of a pre-RNA by RNA. [reaction: see text]
Heuberger
Benjamin D
BD
Department of Chemistry, University of California, Riverside, CA 92521, USA.
Switzer
Christopher
C
D003596:Cytosine / Q000737:chemistry; D006157:Guanosine Monophosphate / Q000737:chemistry; D008956:Models, Chemical; D009690:Nucleic Acid Conformation; D009696:Nucleic Acids / Q000737:chemistry*; D012313:RNA / Q000737:chemistry*; D012260:Ribonucleases / Q000737:chemistry; D013780:Tetroses / Q000737:chemistry*
D009696:Nucleic Acids; D013780:Tetroses; D012313:RNA; D006157:Guanosine Monophosphate; D003596:Cytosine; D012260:Ribonucleases; C073321:erythrose