title: Severe cutaneous hypersensitivity to icodextrin in a continuous ambulatory peritoneal dialysis patient.
abstract: Icodextrin, a glucose polymer, is widely used as an alternative to glucose as the osmotic agent in peritoneal dialysis (PD). We describe a case of a continuous ambulatory peritoneal dialysis patient who developed severe cutaneous hypersensitivity after initiation of icodextrin PD solution. Erythematous skin lesions gradually disappeared after discontinuation of icodextrin PD solution. Although the safety and efficacy of icodextrin PD solution is well documented, clinicians should be mindful of the possibility of severe adverse cutaneous reactions to icodextrin PD solution.
authors.affiliation: Department of Internal Medicine, Yongdong Severance Hospital, College of Medicine, Institute of Kidney Disease, Yonsei University, Seoul-Korea.
authors.forename: Sang Hun
authors.initials: SH
authors.lastname: Lee
authors.forename: Hyeong Cheon
authors.initials: HC
authors.lastname: Park
authors.forename: Soung Rok
authors.initials: SR
authors.lastname: Sim
authors.forename: Soo Jin
authors.initials: SJ
authors.lastname: Chung
authors.forename: Ki Joong
authors.initials: KJ
authors.lastname: Kim
authors.forename: Woo Il
authors.initials: WI
authors.lastname: Park
authors.forename: Soon Won
authors.initials: SW
authors.lastname: Hong
authors.forename: Sung Kyu
authors.initials: SK
authors.lastname: Ha
mesh_terms: D000369:Aged, 80 and over; D015314:Dialysis Solutions / Q000008:administration & dosage / Q000009:adverse effects*; D003875:Drug Eruptions / Q000209:etiology* / Q000473:pathology; D005260:Female; D005936:Glucans / Q000008:administration & dosage / Q000009:adverse effects*; D005947:Glucose / Q000008:administration & dosage / Q000009:adverse effects*; D006801:Humans; D000077607:Icodextrin; D010531:Peritoneal Dialysis, Continuous Ambulatory; D012867:Skin / Q000473:pathology
chemical_list: D015314:Dialysis Solutions; D005936:Glucans; D000077607:Icodextrin; D005947:Glucose