title: Sudden change of a large congenital melanocytic nevus to neurocutaneous melanosis.
abstract: Neurocutaneous melanosis (NCM) is a congenital phakomatosis in which large congenital melanocytic nevi are associated with a benign or malignant melanocytic tumor of the leptomeninges. Because the prognosis of patients with symptomatic NCM is poor, it is essential to monitor the large congenital melanocytic patient regularly for a neurological evaluation. However, it has not been reported how quickly the lesion could appear. We observed a case of NCM suddenly developing in a large congenital melanocytic nevi patient. With this case, the NCM had developed within six months and was aggravated during the subsequent six months.
authors.affiliation: Department of Plastic and Reconstructive Surgery, College of Medicine, Inha University, Incheon, South Korea. cjlee313@hotmail.com
authors.forename: Choong Jae
authors.initials: CJ
authors.lastname: Lee
authors.forename: Jun Ho
authors.initials: JH
authors.lastname: Park
authors.forename: Se Il
authors.initials: SI
authors.lastname: Lee
mesh_terms: D001932:Brain Neoplasms / Q000209:etiology* / Q000601:surgery; D002648:Child; D017809:Fatal Outcome; D006801:Humans; D008297:Male; D008545:Melanoma / Q000209:etiology* / Q000601:surgery; D008548:Melanosis / Q000209:etiology*; D020752:Neurocutaneous Syndromes / Q000209:etiology*; D009508:Nevus, Pigmented / Q000150:complications*; D012878:Skin Neoplasms / Q000150:complications*