Structure of lasiansine from Aconitumnagarum var. lasiandrum.
A new C19-diterpenoid alkaloid, lasiansine (1), was isolated from the roots of Aconitu nagarum var. lasiandrum (Ranunculaceae) together with six known diterpenoid alkaloids. The structure of 1 was elucidated by spectral methods (1H-NMR, 13C-NMR, 2D-NMR, HRMS, IR), and the 13C-NMR spectrum of 16-epipyroaconine (3) and the single-crystal X-ray analysis of its derivative (5) are reported for the first time.
Ji
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Department of Chemistry of Medicinal Natural Products, West China College of Pharmacy, Sichuan University, No. 17, Duan 3, Renmin Nan Road, Chengdu, 610041, China.
Wang
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FP
D031841:Aconitum / Q000737:chemistry*; D002681:China; D002845:Chromatography; D004224:Diterpenes / Q000737:chemistry* / Q000302:isolation & purification; D006576:Heterocyclic Compounds, 4 or More Rings / Q000737:chemistry* / Q000302:isolation & purification; D015394:Molecular Structure; D018517:Plant Roots / Q000737:chemistry*; D010946:Plants, Medicinal / Q000737:chemistry*; D046948:Secologanin Tryptamine Alkaloids / Q000737:chemistry* / Q000302:isolation & purification; D013053:Spectrophotometry
D004224:Diterpenes; D006576:Heterocyclic Compounds, 4 or More Rings; D046948:Secologanin Tryptamine Alkaloids; C518099:lasiansine