Experimental and numerical investigation into leakage effect in injectors of microfluidic devices.
This paper performs an experimental and numerical investigation into low-leakage injectors designed for electrophoresis microchips. The principal material transport mechanisms of electrokinetic migration, fluid flow, and diffusion are considered in developing a mathematical model of the electrophoresis process. Low-leakage injectors designed with injection channels orientated at various included angles are designed and tested. The numerical and experimental results indicate that the injector with a 30 degrees included angle successfully minimizes sample leakage and has an exciting potential for use in high-quality, high-throughput chemical analysis procedures and in many other applications in the field of micro-total analysis systems.
Tsai
Chien-Hsiung
CH
Department of Vehicle Engineering, National Pingtung University of Science and Technology, Pingtung, Taiwan.
Wang
Yao-Nan
YN
Lin
Chiu-Feng
CF
Yang
Ruey-Jen
RJ
Fu
Lung-Ming
LM
D003198:Computer Simulation; D046209:Electrophoresis, Microchip / Q000295:instrumentation*; D017022:Flow Injection Analysis / Q000295:instrumentation*; D046210:Microfluidic Analytical Techniques; D008956:Models, Chemical