title: Natural dibenzoxazepinones from leaves of Carex distachya: Structural elucidation and radical scavenging activity.
abstract: Two new dibenzoxazepinones have been isolated from the leaves of Carex distachya, an herbaceous plant growing in the Mediterranean area. The structures have been elucidated on the basis of their spectroscopic properties. Bidimensional NMR (DQ-COSY, TOCSY, NOESY, ROESY, HSQC, and HMBC) furnished important data useful for the characterization of the molecules. The compounds have been assayed, for the antioxidant activity, by measuring its capacity to scavenge the DPPH, the superoxide anion, and nitric oxide radicals.
authors.affiliation: Dipartimento di Scienze della Vita, Seconda Università degli studi di Napoli, via Vivaldi 43, 81100 Caserta, Italy. antonio.fiorentino@unina2.it
authors.forename: Antonio
authors.initials: A
authors.lastname: Fiorentino
authors.forename: Brigida
authors.initials: B
authors.lastname: D'Abrosca
authors.forename: Severina
authors.initials: S
authors.lastname: Pacifico
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Cefarelli
authors.forename: Piera
authors.initials: P
authors.lastname: Uzzo
authors.forename: Pietro
authors.initials: P
authors.lastname: Monaco
mesh_terms: D001713:Biphenyl Compounds; D031255:Carex Plant / Q000737:chemistry*; D003989:Dibenzoxazepines / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D016166:Free Radical Scavengers / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D009682:Magnetic Resonance Spectroscopy; D009569:Nitric Oxide / Q000737:chemistry; D009580:Nitroblue Tetrazolium; D009599:Nitroprusside / Q000737:chemistry; D010851:Picrates; D010936:Plant Extracts / Q000494:pharmacology; D018515:Plant Leaves / Q000737:chemistry; D021241:Spectrometry, Mass, Electrospray Ionization; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet; D013481:Superoxides / Q000737:chemistry
chemical_list: D001713:Biphenyl Compounds; D003989:Dibenzoxazepines; D016166:Free Radical Scavengers; D010851:Picrates; D010936:Plant Extracts; D013481:Superoxides; D009599:Nitroprusside; D009580:Nitroblue Tetrazolium; D009569:Nitric Oxide; C004931:1,1-diphenyl-2-picrylhydrazyl