title: [The pro-inflammatory role of cytokines in the mechanism of atherosclerosis].
abstract: Investigation of the mechanisms of atherosclerosis has determined that inflammation plays a central role in the development, progression, and outcome of acute coronary syndrome. Although C-reactive protein will remain over time a useful marker, cytokines will continue to be studied in order to understand the mechanisms of acute coronary syndrome and cytokine balance. This short review summarizes the experimental and clinical evidence regarding the role of some cytokines in acute coronary syndrome (interleukin [IL]-8, IL-10, IL-18, IL-2, tumor necrosis factor-alpha, interferon-gamma).
authors.affiliation: Dipartimento di Cardiologia, Università degli Studi, Foggia. opsfco@tin.it
authors.forename: Michele
authors.initials: M
authors.lastname: Correale
authors.forename: Natale Daniele
authors.initials: ND
authors.lastname: Brunetti
authors.forename: Matteo
authors.initials: M
authors.lastname: Di Biase
mesh_terms: D000208:Acute Disease; D000789:Angina, Unstable / Q000276:immunology; D050197:Atherosclerosis / Q000209:etiology* / Q000276:immunology; D016207:Cytokines / Q000276:immunology*; D006801:Humans; D007249:Inflammation / Q000150:complications; D009203:Myocardial Infarction / Q000276:immunology; D013577:Syndrome
chemical_list: D016207:Cytokines