title: Echolucent carotid plaques as a feature in patients with acute coronary syndrome.
abstract: BACKGROUND
  Carotid arterial ultrasound examination may be helpful for screening populations at high risk for acute coronary syndrome (ACS), so the present study was designed to identify the carotid arterial characteristics of patients with ACS.
  
  
  RESULTS
  Carotid ultrasound examinations were performed in 172 patients with ACS, 166 patients with stable coronary artery disease (CAD), and 96 control subjects. Common carotid arterial structures were assessed by the intima - media thickness (IMT), interadventitial diameter (IAD), lumen diameter (LD), the IMT to LD ratio (IMT/LD), and the plaque burden based on the plaque score. Plaque morphology was assessed by the echogenecity based on the gray-scale median (GSM). IMT, IAD, IMT/LD, and plaque score did not differ between the ACS and stable CAD groups. The GSM in the ACS group was lower (47.5+/-25.3, p<0.001) than in the control (70.1+/-22.5) and stable CAD (73.7+/-23.4) groups. Multiple logistic regression analysis showed that the presence of carotid echolucent plaques (GSM <or=60) was an independent predictor of ACS.
  
  
  CONCLUSIONS
  Echolucent carotid plaques were strongly associated with ACS and may be a surrogate marker of high-risk patients.
authors.affiliation: Cardiovascular Division, Institute of Clinical Medicine, University of Tsukuba, Tsukuba, Japan. yo-seo@md.tsukuba.ac.jp
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Seo
authors.forename: Shigeyuki
authors.initials: S
authors.lastname: Watanabe
authors.forename: Tomoko
authors.initials: T
authors.lastname: Ishizu
authors.forename: Naoko
authors.initials: N
authors.lastname: Moriyama
authors.forename: Noriyuki
authors.initials: N
authors.lastname: Takeyasu
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Maeda
authors.forename: Toshiyuki
authors.initials: T
authors.lastname: Ishimitsu
authors.forename: Kazutaka
authors.initials: K
authors.lastname: Aonuma
authors.forename: Iwao
authors.initials: I
authors.lastname: Yamaguchi
mesh_terms: D000368:Aged; D017536:Carotid Artery, Common / Q000000981:diagnostic imaging* / Q000473:pathology; D016893:Carotid Stenosis / Q000000981:diagnostic imaging* / Q000473:pathology; D005260:Female; D006801:Humans; D008297:Male; D008403:Mass Screening; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000473:pathology*; D018616:Ultrasonography, Doppler, Duplex