An enantioselective desymmetrisation approach to C9-substituted trans-hydrindene rings based on a diastereotopic group-selective intramolecular Diels-Alder reaction.
The synthesis of an achiral skipped bis(1,3-diene) substrate was achieved, which was shown to undergo an enantioselective, diastereotopic group-selective, intramolecular Diels-Alder reaction.
Azzi
Nadia
N
University of Southampton, School of Chemistry, Highfield, Southampton, UKSO17 1BJ.
Griffen
Ed
E
Light
Mark
M
Linclau
Bruno
B
D002070:Butadienes / Q000138:chemical synthesis* / Q000737:chemistry; D007192:Indenes / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy / Q000379:methods; D008958:Models, Molecular; D015394:Molecular Structure; D012680:Sensitivity and Specificity; D013237:Stereoisomerism
D002070:Butadienes; D007192:Indenes