title: Dengue in pregnancy.
abstract: This was a retrospective study of patients with dengue infection in pregnancy from year 2000 till 2004. Data were analyzed by looking at the presentation, complications of patient and fetus, and pregnancy outcomes. There was a total of 16 cases with an increasing trend (0.12% in 2003 vs 0.25% in 2004). The mean age of patients was 30.19+/-6.85 years. Fifty percent of patients were multiparae and in their third trimester. The average gestation was 24.44 weeks with 7.5 days being the average duration of ward admission. Tourniquet test was positive in 62.5% of patients. Dengue serology IgM was positive in 50% whereas dengue serology IgG were positive in 68.8% of patients. There were three cases of maternal death. One patient presented as missed abortion. Preterm deliveries happened in 50.0% of the women. There were 4 premature babies, one in-utero fetal death, and two fetuses which suffered acute fetal distress. Three babies required intensive care. One unrelated fetal anomaly resulted in early neonatal death.
authors.affiliation: Department of Obstetrics and Gynecology, Hospital Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia. azlinm@mail.hukm.ukm.my
authors.forename: Nor Azlin Mohamed
authors.initials: NA
authors.lastname: Ismail
authors.forename: Nirmala
authors.initials: N
authors.lastname: Kampan
authors.forename: Zaleha Abdullah
authors.initials: ZA
authors.lastname: Mahdy
authors.forename: Muhammad Abdul
authors.initials: MA
authors.lastname: Jamil
authors.forename: Zainul Rashid Mohd
authors.initials: ZR
authors.lastname: Razi
mesh_terms: D000328:Adult; D003715:Dengue / Q000473:pathology*; D005260:Female; D005333:Fetus / Q000473:pathology*; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D007075:Immunoglobulin M / Q000097:blood; D008296:Malaysia; D011247:Pregnancy; D011256:Pregnancy Outcome; D012189:Retrospective Studies
chemical_list: D007074:Immunoglobulin G; D007075:Immunoglobulin M