[Preparation and properties of medical calcium phosphate cement].
The preparation of tetracalcium phosphate (Ca4(PO4)2O, TTCP)was studied. Then calcium phosphate cement (CPC) was prepared. The setting time, pH value, compressive strength, X-ray diffraction (XRD) and scanning electron microscope (SEM) analysis of CPC were studied. The results show that TTCP containing small amount of CaO can be successfully attained heated at 1 500 degrees C for 6 h in vacuum condition. The initial setting time and final setting time of CPC is 4 min and 15 min, respectively. Its compressive strength is 20 MPa after 1-day immersion and 35 MPa after 7-day immersion. The pH value of the solution changes between 6.4 and 8.9. These properties can satisfy the clinical requirements of CPC. The final product of CPC is flake-like or needle-like hydroxyapatite (Ca5(P04)3OH, HA). The continuous network structure of HA appears in the microstructure, this leads to increase the strength of the material. This CPC can be used as bone substitute material.
Zheng
Zhi
Z
Xiangya the Third Hospital, Central South University, Changsha 410013, China. zheng0813@163.com
Xiang
Qijun
Q
Liu
Yong
Y
Su
Zhean
Z
Wang
Jianlong
J
Xiao
Fei
F
D001843:Bone Cements / Q000138:chemical synthesis / Q000737:chemistry; D002130:Calcium Phosphates / Q000138:chemical synthesis / Q000737:chemistry; D019245:Compressive Strength; D008422:Materials Testing; D013499:Surface Properties; D013718:Tensile Strength
D001843:Bone Cements; D002130:Calcium Phosphates; C020243:calcium phosphate