title: [Significance of urine dipstick test for occult blood in patients with diabetes mellitus].
abstract: OBJECTIVE
  Hematuria is the usual urinary finding in patients with diabetic nephropathy. In this study, prevalence and significance of microhematuria in patients with diabetes mellitus were investigated.
  
  
  METHODS
  Five hundred and forty-two samples from outpatients, who consulted the Department of Diabetes and Metabolism, were categorized into 4 groups according to the results of the urine dipstick test. Group I :258 samples, urinary protein(u-P) 1+ and occult blood (OB) negative, group II: 95 samples: u-P 1+, OB 1+ approximately 3+, group III: 89 samples: u-P 2+ approximately 3+, OB negative, group IV 100 samples u-P 2+ approximately 3+, OB 1+ approximately 3+.
  
  
  RESULTS
  Serum concentrations of creatinine and highly sensitive CRP were both significantly higher in group II than in group I . Those parameters were also significantly higher in group IV than in group III.
  
  
  CONCLUSIONS
  These results indicate that a positive dipstick test for OB may occur in many patients with diabetes mellitus and suggest the progress of renal damage.
authors.affiliation: Department of Clinical Laboratory, Tohoku University Hospital, Japan.
authors.forename: Noriko
authors.initials: N
authors.lastname: Ohisa
authors.forename: Katsumi
authors.initials: K
authors.lastname: Yoshida
authors.forename: Mitsuo
authors.initials: M
authors.lastname: Kaku
authors.forename: Yasushi
authors.initials: Y
authors.lastname: Ishigaki
authors.forename: Yoshitomo
authors.initials: Y
authors.lastname: Oka
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Sato
mesh_terms: D003404:Creatinine / Q000097:blood; D048909:Diabetes Complications / Q000652:urine*; D003928:Diabetic Nephropathies / Q000175:diagnosis* / Q000453:epidemiology; D006417:Hematuria / Q000175:diagnosis* / Q000453:epidemiology; D006801:Humans; D009780:Occult Blood; D015995:Prevalence; D011507:Proteinuria / Q000175:diagnosis; D011934:Reagent Strips; D012680:Sensitivity and Specificity
chemical_list: D011934:Reagent Strips; D003404:Creatinine