title: Processing facial emotions in adults with velo-cardio-facial syndrome: functional magnetic resonance imaging.
abstract: We studied the functional neuroanatomy of social behaviour in velo-cardio-facial syndrome (VCFS) using a facial emotional processing task and functional magnetic resonance imaging in adults with this syndrome and controls matched for age and IQ. The VCFS group had less activation in the right insula and frontal brain regions and more activation in occipital regions. Genetically determined abnormalities in pathways including those involved in emotional processing may underlie deficits in social cognition in people with VCFS.
authors.affiliation: Department of Psychiatry, Academic Medical Centre, Amsterdam, The Netherlands. t.a.vanamelsvoort@amc.uva.nl
authors.forename: Therese
authors.initials: T
authors.lastname: van Amelsvoort
authors.forename: Nicole
authors.initials: N
authors.lastname: Schmitz
authors.forename: Eileen
authors.initials: E
authors.lastname: Daly
authors.forename: Quinton
authors.initials: Q
authors.lastname: Deeley
authors.forename: Hugo
authors.initials: H
authors.lastname: Critchley
authors.forename: Jayne
authors.initials: J
authors.lastname: Henry
authors.forename: Dene
authors.initials: D
authors.lastname: Robertson
authors.forename: Michael
authors.initials: M
authors.lastname: Owen
authors.forename: Kieran C
authors.initials: KC
authors.lastname: Murphy
authors.forename: Declan G
authors.initials: DG
authors.lastname: Murphy
mesh_terms: D000328:Adult; D004062:DiGeorge Syndrome / Q000523:psychology*; D004644:Emotions; D005149:Facial Expression; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D021641:Recognition, Psychology; D012565:Schizophrenic Psychology