Antimicrobial and antioxidant activities of the methanolic extracts of three Salvia species from Tunisia.
This study examines the in vitro antimicrobial and antioxidant activities of the methanolic extracts of three Salvia species from Tunisia: Salvia aegyptiaca L., S. argentea L. and S. verbenaca Ssp. clandestina L. Pugsley. The extracts inhibited the growth of dermatophytes and of bacteria responsible for unpleasant odours to varying degrees; the pathogenic yeasts Candida albicans and Cryptococcus neoformans, the filamentous fungi Aspergillus fumigatus and selected dog otitis bacteria were all resistant to each of the extracts. The extracts were screened for their antioxidant activities using 2,2-diphenyl-1-picrylhydrazyl free radical scavenging and 2,2'-azinobis(3-ethylbenzothiazoline-6-sulphonic acid) test systems, and gave positive results in both tests. The extracts of S. aegyptiaca were the most active in both tests, followed by those of S. verbenaca, then S. argentea. These results confirm the antimicrobial and antioxidant activities of the genus Salvia and underline the potential of these plants either as natural preservatives or in pharmaceutical applications.
Salah
Karima Bel Hadj
KB
Faculté de Pharmacie, Laboratoire des Maladies Transmissibles et Substances Biologiquement Actives, 5000 Monastir, Tunisia.
Mahjoub
Mohamed Ali
MA
Ammar
Samia
S
Michel
Laura
L
Millet-Clerc
Joelle
J
Chaumont
Jean Pierre
JP
Mighri
Zine
Z
Aouni
Mahjoub
M
D000890:Anti-Infective Agents / Q000737:chemistry / Q000633:toxicity*; D000975:Antioxidants / Q000737:chemistry / Q000494:pharmacology*; D052160:Benzothiazoles; D001713:Biphenyl Compounds; D016956:Burkholderia cepacia / Q000187:drug effects; D005609:Free Radicals / Q000378:metabolism; D005658:Fungi / Q000187:drug effects; D000432:Methanol; D010851:Picrates; D010936:Plant Extracts / Q000737:chemistry / Q000494:pharmacology; D018515:Plant Leaves / Q000737:chemistry*; D011550:Pseudomonas aeruginosa / Q000187:drug effects; D027544:Salvia / Q000737:chemistry*; D013045:Species Specificity; D013210:Staphylococcus / Q000187:drug effects; D013451:Sulfonic Acids; D014416:Tunisia
D000890:Anti-Infective Agents; D000975:Antioxidants; D052160:Benzothiazoles; D001713:Biphenyl Compounds; D005609:Free Radicals; D010851:Picrates; D010936:Plant Extracts; D013451:Sulfonic Acids; C002502:2,2'-azino-di-(3-ethylbenzothiazoline)-6-sulfonic acid; C004931:1,1-diphenyl-2-picrylhydrazyl; D000432:Methanol