Correlation between cytogenetic abnormalities in cells and metabolic shifts in children with spinal deformities.
We studied the relationship between cytogenetic abnormalities in buccal epithelial cells and metabolic shifts in children with scoliosis and kyphosis. The incidence of nucleus abnormalities and the corresponding metabolic shifts were found to depend on the presence of spinal deformities and ecological factors. The problem of formation of risk groups for spinal deformities in ecologically unfavorable regions is discussed.
Karganov
Mikhail
M
Institute of General Pathology and Pathophysiology, Russia.
Kozhevnikova
Margarita
M
Aleschenko
Alina
A
Khlebnikova
Nadezhda
N
Dmitrieva
Olga
O
Alchinova
Irina
I
Dmitrieva
Galina
G
Pelevina
Irina
I
Noskin
Leonid
L
D002648:Child; D002869:Chromosome Aberrations; D020732:Cytogenetic Analysis; D004847:Epithelial Cells / Q000166:cytology*; D005260:Female; D006801:Humans; D007738:Kyphosis / Q000378:metabolism*; D008297:Male; D012426:Russia