title: Enhanced catalase-like activity of manganese salen complexes in water: effect of a three-dimensionally fixed auxiliary.
abstract: A new Mn(Salen) complex bearing an ureido group as an auxiliary that is three-dimensionally fixed by a cyclopentane ring fused to the Salen structure was developed. This compound exhibited considerably higher catalase-like activity than the original Mn(Salen), i.e., the cyclopentane-fused Mn(Salen) without the auxiliary, under near-physiological conditions.
authors.affiliation: Graduate School of Pharmaceutical Sciences, Nagoya City University, 3-1 Tanabe-dori, Mizuho-ku, Nagoya, Japan.
authors.forename: Yoritada
authors.initials: Y
authors.lastname: Watanabe
authors.forename: Azusa
authors.initials: A
authors.lastname: Namba
authors.forename: Naoki
authors.initials: N
authors.lastname: Umezawa
authors.forename: Masatoshi
authors.initials: M
authors.lastname: Kawahata
authors.forename: Kentaro
authors.initials: K
authors.lastname: Yamaguchi
authors.forename: Tsunehiko
authors.initials: T
authors.lastname: Higuchi
mesh_terms: D002384:Catalysis; D018360:Crystallography, X-Ray; D003517:Cyclopentanes / Q000737:chemistry; D004789:Enzyme Activation; D005029:Ethylenediamines / Q000138:chemical synthesis / Q000737:chemistry*; D006860:Hydrogen Bonding; D006861:Hydrogen Peroxide / Q000737:chemistry; D008024:Ligands; D008958:Models, Molecular; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000138:chemical synthesis / Q000737:chemistry*; D013237:Stereoisomerism; D013997:Time Factors; D014508:Urea / Q000737:chemistry; D014867:Water / Q000737:chemistry
chemical_list: D003517:Cyclopentanes; D005029:Ethylenediamines; D008024:Ligands; D009942:Organometallic Compounds; D014867:Water; C090577:N,N'-bis(salicylideneamino)ethane-manganese(II); D014508:Urea; D006861:Hydrogen Peroxide