[Effectiveness of infliximab in patients with Behçet syndrome and severe uveoretinitis. Report of five cases].
The efficacy and safety of repeated administration of infliximab was evaluated in five patients (two men, three women) with Behçet syndrome accompanied by severe uveoretinitis. Ocular and extra ocular inflammation was suppressed in all patients during the observation period without any serious adverse reactions. The results in these patients suggests that TNF-á blockade is effective in patients with severe ocular Behçet syndrome.
Merino
Guillermo
G
Departamento de Oftalmología, Clínica Santa María, Santiago, Chile.
Varas
Gonzalo
G
Díaz
Gonzalo
G
Gutiérrez
Miguel
M
Massardo
Loreto
L
Pacheco
Daniel
D
Villarroel
Francisco
F
Cuchacovich
Miguel
M
D000328:Adult; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use*; D000911:Antibodies, Monoclonal / Q000627:therapeutic use*; D001528:Behcet Syndrome / Q000175:diagnosis / Q000188:drug therapy*; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D000069285:Infliximab; D008297:Male; D008875:Middle Aged; D012173:Retinitis / Q000175:diagnosis / Q000188:drug therapy*; D014605:Uveitis / Q000175:diagnosis / Q000188:drug therapy*; D014792:Visual Acuity
D000893:Anti-Inflammatory Agents; D000911:Antibodies, Monoclonal; D000069285:Infliximab