[Inflammation and apoptosis in relation with the effectiveness of bone marrow cell transplantation to patients with chronic heart failure].
The authors analyze the pathogenetic significance of inflammation, immune activation, and apoptosis in the development of heart failure and the functional regeneration of left ventricular myocardium after treatment including autologic bone marrow cell transplantation. The paper shows that autologic bone marrow cell transplantation influences the same mechanisms that cause heart failure, namely inflammation, apoptosis, and neurohumoral mechanisms. Investigations have made it possible to formulate guidelines for the prediction and monitoring of the effects of treatment including autologic bone marrow cell transplantation in patients with heart failure.
Shumakov
V I
VI
Shevchenko
O P
OP
Orlova
O V
OV
Onishchenko
N A
NA
Gureev
S V
SV
D017209:Apoptosis / Q000502:physiology*; D016026:Bone Marrow Transplantation; D016207:Cytokines / Q000097:blood*; D006333:Heart Failure / Q000097:blood / Q000473:pathology / Q000601:surgery; D006352:Heart Ventricles / Q000473:pathology*; D006801:Humans; D016896:Treatment Outcome
D016207:Cytokines