title: Experimental evaluation of a MOSFET dosimeter for proton dose measurements.
abstract: The metal oxide semiconductor field-effect transistor (MOSFET) dosimeter has been widely studied for use as a dosimeter for patient dose verification. The major advantage of this detector is its size, which acts as a point dosimeter, and also its ease of use. The commercially available TN502RD MOSFET dosimeter manufactured by Thomson and Nielsen has never been used for proton dosimetry. Therefore we used the MOSFET dosimeter for the first time in proton dose measurements. In this study, the MOSFET dosimeter was irradiated with 190 MeV therapeutic proton beams. We experimentally evaluated dose reproducibility, linearity, fading effect, beam intensity dependence and angular dependence for the proton beam. Furthermore, the Bragg curve and spread-out Bragg peak were also measured and the linear-energy transfer (LET) dependence of the MOSFET response was investigated. Many characteristics of the MOSFET response for proton beams were the same as those for photon beams reported in previous papers. However, the angular MOSFET responses at 45, 90, 135, 225, 270 and 315 degrees for proton beams were over-responses of about 15%, and moreover the MOSFET response depended strongly on the LET of the proton beam. This study showed that the angular dependence and LET dependence of the MOSFET response must be considered very carefully for quantitative proton dose evaluations.
authors.affiliation: Particle Therapy Division, Research Center for Innovative Oncology, National Cancer Center Hospital East, Japan.
authors.forename: Ryosuke
authors.initials: R
authors.lastname: Kohno
authors.forename: Teiji
authors.initials: T
authors.lastname: Nishio
authors.forename: Tomoko
authors.initials: T
authors.lastname: Miyagishi
authors.forename: Eriko
authors.initials: E
authors.lastname: Hirano
authors.forename: Kenji
authors.initials: K
authors.lastname: Hotta
authors.forename: Mitsuhiko
authors.initials: M
authors.lastname: Kawashima
authors.forename: Takashi
authors.initials: T
authors.lastname: Ogino
mesh_terms: D055592:Biophysical Phenomena; D001703:Biophysics; D006801:Humans; D018499:Linear Energy Transfer; D008670:Metals; D019047:Phantoms, Imaging; D061766:Proton Therapy; D011874:Radiometry / Q000295:instrumentation* / Q000706:statistics & numerical data; D011882:Radiotherapy, High-Energy; D012666:Semiconductors; D014173:Transistors, Electronic
chemical_list: D008670:Metals