title: Development of acromegaly in a patient with anorexia nervosa: pathogenetic and diagnostic implications.
abstract: Anorexia nervosa (AN) is a psychosomatic disorder characterized by an alteration in body image, resulting in eating abnormalities that lead to malnutrition associated with secondary endocrinological disturbances. AN is associated with high levels of GH and low levels of IGF-I, suggestive of a nutritionally acquired lack of GH action or GH resistance and of an unbalanced hypothalamic GH neuroregulation with GHRH prevalence on SS tone. In this clinical report, we describe the development of acromegaly in a patient affected by AN and we discuss pathogenetic and diagnostic implications.
authors.affiliation: Internal Medicine, Treviso Hospital, Brescia, Italy.
authors.forename: E
authors.initials: E
authors.lastname: de Menis
authors.forename: M
authors.initials: M
authors.lastname: Gola
authors.forename: A
authors.initials: A
authors.lastname: Giustina
mesh_terms: D000172:Acromegaly / Q000097:blood / Q000175:diagnosis* / Q000209:etiology*; D000856:Anorexia Nervosa / Q000097:blood / Q000150:complications* / Q000175:diagnosis*; D003937:Diagnosis, Differential; D005260:Female; D019004:Galanin / Q000008:administration & dosage; D019382:Human Growth Hormone / Q000097:blood; D006801:Humans; D007262:Infusions, Intravenous; D007334:Insulin-Like Growth Factor I / Q000032:analysis; D008875:Middle Aged
chemical_list: D019382:Human Growth Hormone; D007334:Insulin-Like Growth Factor I; D019004:Galanin