[Primary cytomegalovirus infection and thrombophlebitis/pulmonary embolism].
A young woman was admitted to hospital with suspected pyelonephritis. Due to prolonged fever, further investigations were done and showed a thrombosis in her femoral vein; X-ray and lung scintigraphy revealed a pulmonary embolism. Blood tests showed lymphocytosis, and a primary cytamegalovirus (CMV) infection was confirmed by serology and PCR. The patient was a smoker and obese and was taking oral contraceptives; a factor V Leiden mutation was also found. Deep-vein thrombosis is a rare but severe complication of a primary CMV infection that is also seen in immunocompetent persons.
Welinder
Jakob Gjesing
JG
Statens Serum Institut, Virologisk Afdeling. jwelinder@dadlnet.dk
Orholm
Marianne Kirsten
MK
Böttiger
Blenda
B
D000328:Adult; D003586:Cytomegalovirus Infections / Q000175:diagnosis*; D003937:Diagnosis, Differential; D005165:Factor V / Q000235:genetics; D005260:Female; D006801:Humans; D017354:Point Mutation; D011655:Pulmonary Embolism / Q000175:diagnosis* / Q000209:etiology / Q000821:virology; D012307:Risk Factors; D013924:Thrombophlebitis / Q000175:diagnosis* / Q000209:etiology / Q000821:virology
C095381:factor V Leiden; D005165:Factor V