title: The relationship between nail- and distal phalangeal bone involvement severity in patients with psoriasis.
abstract: We aimed to investigate the relationship between nail involvement and joint manifestations and whether there was a correlation between nail psoriasis severity and bone manifestations in psoriatic patients without symptomatic psoriatic arthritis in plaque type psoriasis. Thirty-one patients with nail involvement (16 men, 15 women, mean age 45.29+/-18.73) and 39 patients without nail involvement (16 men, 23 women, mean age 38.41+/-17.33) were enrolled in the study. X-ray of the hands and feet with magnification were performed. The distal interphalangeal (DIP) joint and bone (tuft of terminal phalanx) were evaluated. A scoring method was performed on the patients with nail involvement. There was no difference in DIP joint involvement in patients with or without finger- and toenail involvement (p=0.085 and p=0.062, respectively). However, the prevalence of bone involvement was higher in patients with finger- and toenail involvement than without finger- and toenail involvement (p=0.039 and p=0.021, respectively). A positive correlation was also determined between finger- and toenail psoriasis severity and bone involvement severity (r=0.379, p=0.001 and r=0.288, p=0.015).
authors.affiliation: Department of Dermatology, Faculty of Medicine, Mustafa Kemal University, Antakya, Turkey. gserarslan@hotmail.com
authors.forename: Gamze
authors.initials: G
authors.lastname: Serarslan
authors.forename: Hayal
authors.initials: H
authors.lastname: Güler
authors.forename: Sinem
authors.initials: S
authors.lastname: Karazincir
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D005260:Female; D005384:Finger Joint / Q000473:pathology; D050278:Finger Phalanges / Q000473:pathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009262:Nails / Q000473:pathology*; D011565:Psoriasis / Q000473:pathology*; D012720:Severity of Illness Index; D014033:Toe Joint / Q000473:pathology; D050277:Toe Phalanges / Q000473:pathology*