Point mutations in mitochondrial topoisomerase enzymes of Trypanosoma congolense are not involved in isometamidium resistance.
Delespaux
V
V
Institute of Tropical Medicine, Nationalestraat 155, B-2000 Antwerp, Belgium. vdelespaux@itg.be
Geysen
D
D
Geerts
A S
AS
D000818:Animals; D026942:DNA Topoisomerases / Q000235:genetics* / Q000378:metabolism*; D004351:Drug Resistance; D008928:Mitochondria / Q000201:enzymology*; D010617:Phenanthridines / Q000494:pharmacology*; D017354:Point Mutation / Q000235:genetics*; D014348:Trypanosoma congolense / Q000187:drug effects / Q000201:enzymology* / Q000235:genetics* / Q000302:isolation & purification
D010617:Phenanthridines; C000702:isometamidium chloride; D026942:DNA Topoisomerases