Fluorescently tagged polymer bioconjugates from protein derived macroinitiators.
BSA and lysozyme have been transformed into macroinitiators for living radical polymerisation and used to produce well-defined bioconjugates which can be fluorescently labelled providing a versatile strategy for the preparation of bioconjugates which is complementary to traditional PEGylation.
Nicolas
Julien
J
Department of Chemistry, University of Warwick, Coventry, UKCV4 7AL.
San Miguel
Veronica
V
Mantovani
Giuseppe
G
Haddleton
David M
DM
D000818:Animals; D001704:Biopolymers / Q000737:chemistry; D002417:Cattle; D002851:Chromatography, High Pressure Liquid; D004591:Electrophoresis, Polyacrylamide Gel; D005456:Fluorescent Dyes / Q000737:chemistry*; D006576:Heterocyclic Compounds, 4 or More Rings / Q000737:chemistry*; D015394:Molecular Structure; D009113:Muramidase / Q000737:chemistry*; D011092:Polyethylene Glycols / Q000737:chemistry*; D012235:Rhodamines / Q000737:chemistry*; D012710:Serum Albumin, Bovine / Q000737:chemistry*
D001704:Biopolymers; D005456:Fluorescent Dyes; D006576:Heterocyclic Compounds, 4 or More Rings; D012235:Rhodamines; C516130:hostasol; D012710:Serum Albumin, Bovine; D011092:Polyethylene Glycols; D009113:Muramidase; C029773:rhodamine B