title: Predictive factors for pregnancy hypertension in primiparous adolescents: analysis of prenatal care, ABPM and microalbuminuria.
abstract: OBJECTIVE
  To quantify PH prevalence in primiparous adolescents; define predictive factors for the occurrence of PH and its impact on newborns.
  
  
  METHODS
  We followed 29 primiparous adolescents from the prenatal period through the 12th week of the puerperium, with a mean of sixteen years of age, served at the Outpatient Facility for Adolescents of Maternidade Escola Assis Chateaubriand (MEAC) of Universidade Federal do Ceará (Fortaleza, Brazil). The pregnant adolescents were divided into two groups, that is, those who remained normotensive (Group I) and those who developed PH (Group II). The variables investigated in the assessment of the value of predictability for the development of PH were anthropometric measures, socioeconomic aspects, smoking habit, inheritance for SAH (father/mother), prenatal tests requested in the first prenatal care visit in addition to microalbuminuria and ambulatory blood pressure monitoring (ABPM) in the 28th week of gestation. The pregnant adolescents were followed up at delivery and late puerperium (12th week after the puerperium). The newborns to the mothers included in our study were assessed at birth according to the Apgar score and the Capurro method, for weight, height and perinatal hypoxia.
  
  
  RESULTS
  The prevalence of PH was 51.7%. Inheritance for SAH presented the highest predictive value for PH with an odds ratio of 10.99. Diastolic arterial pressure equal to or above 70 mmHg at the gestational age of 35 weeks was statistically significant as a predictive value for PH. At ABPM we found a predictive value for PH: diastolic pressure load during alertness, diastolic and systolic pressure load during night sleep, pressure variability and maximum diastolic pressure during sleep. Specifically a maximum diastolic arterial pressure (DAP) at ABPM during the period of night sleep (3)64 mmHg presented an odds ratio of 6 for PH with a sensitivity of 80% and a specificity of 60% for the development of PH.
  
  
  CONCLUSIONS
  The research for PH predictive factors in primiparous adolescents showed to be easy to apply and useful to stratify high-risk pregnant women as regards the development of PH.
authors.affiliation: Maternidade Escola Assis Chateaubriand, Centro Integrado de Hipertensão e Diabetes, Fortaleza, CE, Brazil. rcoeli@cardiol.br
authors.forename: Regina Coeli Marques
authors.initials: RC
authors.lastname: de Carvalho
authors.forename: Henry de Holanda
authors.initials: Hde H
authors.lastname: Campos
authors.forename: Zenilda Vieira
authors.initials: ZV
authors.lastname: Bruno
authors.forename: Rosa Maria Salani
authors.initials: RM
authors.lastname: Mota
mesh_terms: D000293:Adolescent; D000419:Albuminuria / Q000150:complications / Q000175:diagnosis*; D018660:Blood Pressure Monitoring, Ambulatory; D001938:Brazil / Q000453:epidemiology; D004812:Epidemiologic Methods; D005260:Female; D006801:Humans; D046110:Hypertension, Pregnancy-Induced / Q000175:diagnosis / Q000453:epidemiology* / Q000209:etiology; D007231:Infant, Newborn; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000175:diagnosis / Q000453:epidemiology* / Q000209:etiology; D011256:Pregnancy Outcome; D011295:Prenatal Care