Detection of Mycoplasma genitalium, Mycoplasma hominis, Ureaplasma urealyticum, and Ureaplasma parvum DNAs in urine from asymptomatic healthy young Japanese men.
The aim of this study was to estimate the detection rates of Mycoplasma and Ureaplasma, which are presumptive causes of sexually transmitted diseases (STDs), in young men in Sapporo, Japan. In addition, we examined the associations among Chlamydia trachomatis, Mycoplasma, and Ureaplasma. A survey of 100 asymptomatic healthy male volunteers was carried out. C. trachomatis, Mycoplasma genitalium, Mycoplasma hominis, Ureaplasma urealyticum, and Ureaplasma parvum in first-voided urine specimens were detected by polymerase chain reaction assay. Detection rates were 1% for M. genitalium, 4% for M. hominis, 12% for U. urealyticum, and 23% for U. parvum. C. trachomatis was detected in 6% of samples. No M. hominis, U. urealyticum, or U. parvum was detected simultaneously in any sample positive for C. trachomatis. The detection rate of urinary M. genitalium was extremely low, which is similar to previous reports from Japan. The detection rates of urethral U. urealyticum and U. parvum were significantly related to sexual activity. We need to determine whether these pathogens have a role in the sexual transmission of disease or just in colonization.
Takahashi
Satoshi
S
Department of Urology, Sapporo Medical University School of Medicine, S. 1, W. 16, Chuo-ku, Sapporo, 060-8543, Japan. stakahas@sapmed.ac.jp
Takeyama
Koh
K
Miyamoto
Shintaro
S
Ichihara
Kohji
K
Maeda
Toshihiro
T
Kunishima
Yasuharu
Y
Matsukawa
Masanori
M
Tsukamoto
Taiji
T
D000293:Adolescent; D000328:Adult; D002690:Chlamydia Infections / Q000453:epidemiology / Q000382:microbiology; D002692:Chlamydia trachomatis / Q000235:genetics / Q000302:isolation & purification; D004269:DNA, Bacterial / Q000652:urine*; D006801:Humans; D007564:Japan / Q000453:epidemiology; D008297:Male; D009174:Mycoplasma / Q000235:genetics* / Q000302:isolation & purification*; D009175:Mycoplasma Infections / Q000453:epidemiology / Q000382:microbiology / Q000652:urine*; D045704:Mycoplasma genitalium / Q000235:genetics / Q000302:isolation & purification; D019535:Mycoplasma hominis / Q000235:genetics / Q000302:isolation & purification; D012725:Sexual Behavior; D012749:Sexually Transmitted Diseases / Q000453:epidemiology / Q000382:microbiology / Q000652:urine*; D014509:Ureaplasma / Q000235:genetics* / Q000302:isolation & purification; D016869:Ureaplasma Infections / Q000453:epidemiology / Q000382:microbiology / Q000652:urine*; D016990:Ureaplasma urealyticum / Q000235:genetics / Q000302:isolation & purification
D004269:DNA, Bacterial