[Ventricular fibrillation during induction of anesthesia in a patient with polycythemia vera].
A 53-year-old male patient complained of the pain with bilateral hip area and right hip joint and underwent emergency arthroscopy and drainage. Twenty-eight years before, he had suffered from gout and from his abnormal increase of blood cells was diagnosed as polycythemia vera. The laboratory examination at admission showed a marked increase of hemoglobin (17.7 g x dl(-1)) and hematocrit (69.5%). Immediately before induction of anesthesia, 1000 ml of phlebotomy was performed with large fluid infusion. After induction of anesthesia and oro-tracheal intubation, electrocardiogram (ECG) suddenly showed ventricular fibrillation (Vf). Defibrillation was applied and the ECG recovered to sinus rhythm, but 30 min later, ECG showed Vf, again. The increased blood viscosity with polycythemia might have induced coronary ischemia and fatal arrhythmia in the patient. Vigourous hemodilution before surgery should have been performed as prophylactic management of the cardiac episodes in this patient.
Uchisaki
Sakiko
S
Department of Anesthesiology and Intensive Care, Hamamatsu University School of Medicine, Hamamatsu 431-3192.
Matsui
Genichiro
G
Sato
Naoshi
N
Nakajima
Yoshiki
Y
Adachi
Yushi
Y
Sano
Hideki
H
Doi
Matsuyuki
M
Shiraishi
Yoshito
Y
Sato
Shigehito
S
D000768:Anesthesia, General / Q000009:adverse effects*; D004630:Emergencies; D006073:Gout / Q000150:complications; D006801:Humans; D008297:Male; D008875:Middle Aged; D011087:Polycythemia Vera / Q000150:complications*; D014693:Ventricular Fibrillation / Q000209:etiology*