Natural dibenzoxazepinones from leaves of Carex distachya: Structural elucidation and radical scavenging activity.
Two new dibenzoxazepinones have been isolated from the leaves of Carex distachya, an herbaceous plant growing in the Mediterranean area. The structures have been elucidated on the basis of their spectroscopic properties. Bidimensional NMR (DQ-COSY, TOCSY, NOESY, ROESY, HSQC, and HMBC) furnished important data useful for the characterization of the molecules. The compounds have been assayed, for the antioxidant activity, by measuring its capacity to scavenge the DPPH, the superoxide anion, and nitric oxide radicals.
Fiorentino
Antonio
A
Dipartimento di Scienze della Vita, Seconda Università degli studi di Napoli, via Vivaldi 43, 81100 Caserta, Italy. antonio.fiorentino@unina2.it
D'Abrosca
Brigida
B
Pacifico
Severina
S
Cefarelli
Giuseppe
G
Uzzo
Piera
P
Monaco
Pietro
P
D001713:Biphenyl Compounds; D031255:Carex Plant / Q000737:chemistry*; D003989:Dibenzoxazepines / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D016166:Free Radical Scavengers / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D009682:Magnetic Resonance Spectroscopy; D009569:Nitric Oxide / Q000737:chemistry; D009580:Nitroblue Tetrazolium; D009599:Nitroprusside / Q000737:chemistry; D010851:Picrates; D010936:Plant Extracts / Q000494:pharmacology; D018515:Plant Leaves / Q000737:chemistry; D021241:Spectrometry, Mass, Electrospray Ionization; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet; D013481:Superoxides / Q000737:chemistry
D001713:Biphenyl Compounds; D003989:Dibenzoxazepines; D016166:Free Radical Scavengers; D010851:Picrates; D010936:Plant Extracts; D013481:Superoxides; D009599:Nitroprusside; D009580:Nitroblue Tetrazolium; D009569:Nitric Oxide; C004931:1,1-diphenyl-2-picrylhydrazyl