title: Clinical inquiries: When are antibiotics indicated for acute COPD exacerbations?
abstract: Antibiotics (including those given orally) reduce mortality and treatment failures for hospitalized patients with acute exacerbations of chronic obstructive pulmonary disease (COPD) (strength of recommendation [SOR]: A, based on systematic reviews). Antibiotics may be prescribed in the outpatient setting for those with severe exacerbations (SOR: C, based on expert opinion).
authors.affiliation: Valley Medical Center Family Medicine Residency, Renton, WA, USA.
authors.forename: Emily
authors.initials: E
authors.lastname: Balser
authors.forename: Jon O
authors.initials: JO
authors.lastname: Neher
authors.forename: Sarah
authors.initials: S
authors.lastname: Safranek
authors.forename: Julie
authors.initials: J
authors.lastname: Taraday
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D001993:Bronchodilator Agents / Q000627:therapeutic use; D018849:Controlled Clinical Trials as Topic; D019317:Evidence-Based Medicine; D006801:Humans; D017410:Practice Guidelines as Topic; D029424:Pulmonary Disease, Chronic Obstructive / Q000188:drug therapy* / Q000517:prevention & control; D055502:Secondary Prevention; D012720:Severity of Illness Index; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents; D001993:Bronchodilator Agents