title: Changes within the thyroid axis during the course of critical illness.
abstract: This article reviews the mechanisms behind the observed changes in plasma thyroid hormone levels in the acute phase and the prolonged phase of critical illness. It focuses on the neuroendocrinology of the low triiodothyronine syndrome and on thyroid hormone metabolism by deiodination and transport.
authors.affiliation: Department of Intensive Care, Catholic University of Leuven, Leuven, Belgium.
authors.forename: Liese
authors.initials: L
authors.lastname: Mebis
authors.forename: Yves
authors.initials: Y
authors.lastname: Debaveye
authors.forename: Theo J
authors.initials: TJ
authors.lastname: Visser
authors.forename: Greet
authors.initials: G
authors.lastname: Van den Berghe
mesh_terms: D003422:Critical Care / Q000379:methods; D016638:Critical Illness / Q000628:therapy; D006801:Humans; D007030:Hypothalamo-Hypophyseal System / Q000503:physiopathology*; D010913:Pituitary-Adrenal System / Q000503:physiopathology*; D013961:Thyroid Gland / Q000503:physiopathology*; D013963:Thyroid Hormones / Q000502:physiology
chemical_list: D013963:Thyroid Hormones