title: New treatment strategies against hepatitis C viral infection.
abstract: Treatment of hepatitis C virus infection is currently based on a combination of pegylated interferon and ribavirin. Because efficacy of this therapy remains suboptimal and side effects sometimes problematic, major efforts have been put forward by scientists and the pharmaceutical industry to develop alternative treatments for this chronic infection. Over the past few years, clinical studies performed with some of these new agents have been presented at major international meetings. The present paper aims to review the rationale underlying the development of these new forms of treatment as well as the current available data concerning their clinical efficacy.
authors.affiliation: Service d'hepatologie, Hopital Saint-Luc du CHUM, Montreal, Canada. Marc.Bilodeau@umontreal.ca
authors.forename: Marc
authors.initials: M
authors.lastname: Bilodeau
authors.forename: Daniel
authors.initials: D
authors.lastname: Lamarre
mesh_terms: D000998:Antiviral Agents / Q000627:therapeutic use*; D006526:Hepatitis C / Q000188:drug therapy*; D006801:Humans; D017410:Practice Guidelines as Topic; D016896:Treatment Outcome
chemical_list: D000998:Antiviral Agents