Endocrine disrupting chemicals: human exposure and health risks.
Endocrine disrupting chemicals (EDCs) have been emphasized due to their threats in fertility, intelligence, and survival. For the last decade, many researchers have investigated EDC-health outcome. However, EDC responses in human were not clearly clarified through experimental and epidemiological data. Therefore, considering particular status of EDC endpoints, we suggest that one of the best ways to prevent unknown health risks from EDCs is to perform exposure monitoring or to do surveillance for EDC release into the environment. For this purpose, this review considers exposure status of EDCs, and EDC-related health risks, focusing on the mainly highlighted EDCs, such as dioxins/PCBs, DDT/DDE, bisphenol A, phthalates, alkylphenols, and phytoestrogens. We also reviewed tobacco, a mixed source of EDC-related endocrine disorders.
Yang
Mihi
M
Department of Toxicology, College of Pharmacy, Sookmyung Women's University, Yongsan-Ku, Seoul, Republic of Korea. myang@sookmyung.ac.kr
Park
Mi Seon
MS
Lee
Ho Sun
HS
D000818:Animals; D052244:Endocrine Disruptors / Q000737:chemistry; D004700:Endocrine System Diseases / Q000139:chemically induced; D004781:Environmental Exposure; D004782:Environmental Health; D004785:Environmental Pollutants / Q000737:chemistry; D006801:Humans; D015394:Molecular Structure; D012307:Risk Factors
D052244:Endocrine Disruptors; D004785:Environmental Pollutants