Long-term and short-term alcohol consumption and levels of C-reactive protein.
The association between alcohol consumption and CRP was evaluated in a longitudinal study among 72 middle aged adults for whom 572 repeated measurements of CRP were obtained. Short- and long-term alcohol consumption were analyzed using moving windows of average alcohol consumption levels to establish a dose-response relationship. To control for intra-individual dependence of measurements, generalised estimating equations were used. Average alcohol consumption during the last 12 months showed a clear U-shaped relationship with CRP-levels, with lowest levels found for moderate alcohol consumption of less than 16 g/day. For short-term alcohol consumption no association was found.
Raum
Elke
E
Gebhardt
Katja
K
Buchner
Matthias
M
Schiltenwolf
Marcus
M
Brenner
Hermann
H
D000328:Adult; D000428:Alcohol Drinking / Q000097:blood*; D002097:C-Reactive Protein / Q000378:metabolism*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D013995:Time
D002097:C-Reactive Protein