Lamivudine reverses severe acute hepatitis B and pancytopenia after renal transplantation: a case report.
Pancytopenia is rare after acute hepatitis B infection. The use of lamivudine in the treatment of acute hepatitis B-associated pancytopenia in renal transplant recipients has not been documented. Herein we reported a 21-year-old woman who was infected with acute hepatitis B 6 months after renal transplantation, a condition complicated by pancytopenia. Lamivudine reversed the acute hepatitis in 1 month and the pancytopenia after 3 months, without a change in renal function. Lamivudine was maintained for 2 years without a hepatitis flare-up after 4 years.
Wang
Y-C
YC
Division of Nephrology, Department of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.
Kuo
M-C
MC
Hung
C-C
CC
Hwang
S-J
SJ
Tsai
J-C
JC
Chen
H-C
HC
D000328:Adult; D005260:Female; D006509:Hepatitis B / Q000188:drug therapy*; D006801:Humans; D007676:Kidney Failure, Chronic / Q000601:surgery; D016030:Kidney Transplantation / Q000009:adverse effects*; D019259:Lamivudine / Q000627:therapeutic use*; D008111:Liver Function Tests; D010198:Pancytopenia / Q000188:drug therapy* / Q000821:virology; D016896:Treatment Outcome
D019259:Lamivudine