title: [Evaluation of a method to reduce the number of sentinel nodes removed in melanoma patients: prospective study].
abstract: BACKGROUND
  Since 1992, sentinel node (SLN) biopsy was generally applied to melanoma for carcinologic staging. Literature points out an increase of nodes removed for each procedure. It means to a high cost for this procedure and it wanders from the defining concept of SLN. The aim of our study was to evaluate whether, we can minimize number of SLN removed, without influencing the reliability of carcinologic staging.
  
  
  METHODS
  We conducted a prospective study about 50 patients with stage one melanoma. For each patient, the SLN was identified with hand-held gamma probe technique. We removed only the hottest and all nodes greater than 70% of the hottest. We analysed the characteristics of melanoma, the success rate of this procedure, how many nodes have been removed and how many have had micro-metastases. This result was compared to two main studies with chi(2) test.
  
  
  RESULTS
  The success rate of this technique was 100%. We dissected 1,3 SLN for each patient, with 22% positive SLN. Statistical analyse pointed out a better selectivity of our study, rate of pathological positivity and recurrence was alike.
  
  
  CONCLUSIONS
  Our technique decreasing number of removed SLN is reliable. A minimal number of nodes doesn't distort sensitivity of carcinologic staging, and reduce cost of the procedure.
authors.affiliation: Service de chirurgie maxillofaciale et plastique, hôpital général, CHU de Dijon, 3, rue Faubourg-Raines, 21000 Dijon, France. natacha.kadlub@wanadoo.fr
authors.forename: N
authors.initials: N
authors.lastname: Kadlub
authors.forename: O
authors.initials: O
authors.lastname: Trost
authors.forename: S
authors.initials: S
authors.lastname: Dalac
authors.forename: A
authors.initials: A
authors.lastname: Berriolo
authors.forename: T
authors.initials: T
authors.lastname: Ponelle
authors.forename: G
authors.initials: G
authors.lastname: Malka
authors.forename: A
authors.initials: A
authors.lastname: Danino
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008197:Lymph Node Excision; D008297:Male; D008545:Melanoma / Q000473:pathology*; D008875:Middle Aged; D011446:Prospective Studies; D021701:Sentinel Lymph Node Biopsy; D012878:Skin Neoplasms / Q000473:pathology*