Non-Hodgkin's lymphoma of mucosa-associated lymphoid tissue.
The concept of mucosa-associated lymphoid tissue (MALT) lymphomas was introduced by Isaacson and Wright [Cancer 1983; 52:1410-1416] in 1983. After more than 20 years of clinical research MALT lymphomas are now recognized as a distinct subtype of non-Hodgkin's lymphoma (NHL) with unique pathogenic, histological, and clinical features. Although this subtype of NHL occurs frequently, optimal management remains elusive. This manuscript reviews features of the clinical presentation, diagnosis, pathology, molecular characteristics, and management of both gastric and non-gastric MALT lymphoma.
Cohen
Seth M
SM
St. Luke's-Roosevelt Hospital Center, New York, NY 10019, USA.
Petryk
Magdalena
M
Varma
Mala
M
Kozuch
Peter S
PS
Ames
Elizabeth D
ED
Grossbard
Michael L
ML
D006801:Humans; D018442:Lymphoma, B-Cell, Marginal Zone / Q000175:diagnosis / Q000235:genetics / Q000628:therapy; D008228:Lymphoma, Non-Hodgkin / Q000175:diagnosis / Q000235:genetics / Q000628:therapy; D009367:Neoplasm Staging; D016896:Treatment Outcome