title: Hemodynamic evaluation of the posterior ciliary circulation in exfoliation syndrome and exfoliation glaucoma.
abstract: BACKGROUND
  Previous studies have reported impaired blood flow in the ophthalmic artery (OA) and central retinal artery (CRA) in exfoliation syndrome and exfoliation glaucoma. This study evaluates blood flow at the long and short posterior ciliary arteries (LPCA and SPCA, respectively) in these conditions.
  
  
  METHODS
  Consecutively examined candidates for cataract surgery were included. Only one eye (OD) was included in the analyses for consistency. Patients were classified into non-glaucoma and non-exfoliation (controls), primary open angle glaucoma (POAG), exfoliation syndrome and exfoliation glaucoma groups, based on the findings of the OD. Sixty-eight patients (41 males, 60.3%) were included. Color Doppler imaging (CDI) of the nasal and temporal branches of LPCA and SPCA was performed using a 7.5 Mhz probe. The peak systolic velocity (PSV), end diastolic velocity (EDV) and resistivity index (RI) were recorded for the examined vessels.
  
  
  RESULTS
  EDV at the LPCA was significantly lower in exfoliation syndrome and glaucoma, compared with controls and POAG respectively. EDV was significantly lower and RI was significantly higher at the SPCA in exfoliation glaucoma, compared with exfoliation, whereas respective differences were statistically not significant between controls and POAG.
  
  
  CONCLUSIONS
  The hemodynamic impairment at the LPCA in exfoliation syndrome and glaucoma supports an association between exfoliation and ischemic stress at the anterior ocular segment.
authors.affiliation: Department of Ophthalmology, Democritus University of Thrace, Alexandroupolis, Greece. edetorak@med.duth.gr
authors.forename: Efstathios T
authors.initials: ET
authors.lastname: Detorakis
authors.forename: Athanassios K
authors.initials: AK
authors.lastname: Achtaropoulos
authors.forename: Eleni E
authors.initials: EE
authors.lastname: Drakonaki
authors.forename: Vassilios P
authors.initials: VP
authors.lastname: Kozobolis
mesh_terms: D001775:Blood Circulation; D001783:Blood Flow Velocity; D019842:Ciliary Arteries / Q000000981:diagnostic imaging / Q000502:physiology*; D017889:Exfoliation Syndrome / Q000000981:diagnostic imaging / Q000503:physiopathology*; D005260:Female; D005902:Glaucoma, Open-Angle / Q000000981:diagnostic imaging / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012039:Regional Blood Flow / Q000502:physiology; D018615:Ultrasonography, Doppler, Color