title: Symptom change in women with overactive bladder after extracorporeal magnetic stimulation: a prospective trial.
abstract: The purpose of this study was to prospectively evaluate symptom change after discontinuation of extracorporeal magnetic stimulation (EMS) in women with overactive bladder (OAB). A total of 48 women with OAB were included. We applied 10 Hz of repetitive magnetic stimulation with a "magnetic chair" for 20 min, twice weekly for 8 weeks. Changes in OAB symptoms at 2, 12, and 24 weeks after discontinuing the EMS were evaluated. Twenty-seven (56.3%) patients were cured compared with the baseline at 2 weeks: the cure rate was determined as 68.8% (33/48 patients), 56.3% (27/48), and 50% (8/16) for urgency, frequency, and urge incontinence, respectively. The mean number of voids per 24 h was decreased by 42.8% (from 14.5 +/- 4.3, to 8.3 +/- 1.5, P < 0.001) at 2 weeks after treatment. Maximum voided volume did not change significantly, but the mean voided volume increased significantly after stimulation. Twenty-six (96.3%) patients among the 27 patients who achieved a cure at 2 weeks, maintained improvement at 24 weeks; the therapeutic effect on urgency, frequency, and urge incontinence persisted in 26 (78.8%) of 33 patients, 26 (96.3%) of 27 patients, and six (75%) of eight patients, respectively. There were no significant changes in urodynamic parameters. Of the 14 patients with detrusor overactivity, the condition was no longer observed in four (28.6%) patients. EMS has a beneficial effect on women with OAB. Our data suggest EMS may have a significant carry-over effect in well-selected OAB patients.
authors.affiliation: Department of Urology, Cheil General Hospital, Sungkyunkwan University School of Medicine, 1-19 Mukjeong-dong, Jung-gu, Seoul, 100-380, South Korea. jhchoe@skku.edu
authors.forename: Jin Ho
authors.initials: JH
authors.lastname: Choe
authors.forename: Myung-Soo
authors.initials: MS
authors.lastname: Choo
authors.forename: Kyu-Sung
authors.initials: KS
authors.lastname: Lee
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008280:Magnetics / Q000627:therapeutic use*; D008875:Middle Aged; D011446:Prospective Studies; D053201:Urinary Bladder, Overactive / Q000503:physiopathology / Q000628:therapy*; D014563:Urodynamics