title: Nasal insertion of St John's wort: an unusual cause of epistaxis.
abstract: We report a case of severe unilateral epistaxis requiring surgical arrest of bleeding, via endoscopic sphenopalatine artery ligation and anterior ethmoidal artery ligation. This followed recreational nasal insertion of St John's wort (Hypericum perforatum). Interactions between this substance and prescribed drugs have been described following oral ingestion. However, this unusual case highlights a further, worrying potential rhinological side effect of this substance.
authors.affiliation: Department of Otolaryngology, Head and Neck Surgery, North Glasgow University Hospitals, Gartnavel General Hospital, Glasgow, Scotland, UK. david.crampsey@btinternest.com
authors.forename: D P
authors.initials: DP
authors.lastname: Crampsey
authors.forename: C M
authors.initials: CM
authors.lastname: Douglas
authors.forename: L D
authors.initials: LD
authors.lastname: Cooke
mesh_terms: D000281:Administration, Intranasal; D000328:Adult; D004347:Drug Interactions; D004844:Epistaxis / Q000209:etiology* / Q000601:surgery; D006801:Humans; D020902:Hypericum / Q000009:adverse effects*; D008297:Male; D008517:Phytotherapy / Q000009:adverse effects* / Q000379:methods; D010936:Plant Extracts / Q000009:adverse effects
chemical_list: D010936:Plant Extracts