title: Plaque removal by young children using old and new toothbrushes.
abstract: There is inconclusive evidence about the relationship between toothbrush wear and plaque removal. This randomized cross-over clinical trial aimed to validate or invalidate non-inferiority in the plaque-removal efficacy of old vs. new toothbrushes in the hands of 7- and 8-year-old children. The lower limit for non-inferiority was set a priori as a difference in plaque score<15%. Children (n=101) brushed, in the first session, with either their 14-month-old toothbrush or a new one, and in the second session vice versa. The mean Quigley-Hein plaque score, before and after children brushed with old brushes, was 2.9 and 2.4, and with new brushes 2.8 and 2.1. The plaque score after they brushed with the new toothbrush was 10.9% lower (p<0.001) than after they brushed with the old toothbrush. The confidence interval of 7.6%-13.9% was within the acceptance band (<15%), and non-inferiority of old toothbrushes in the hands of these children was validated.
authors.affiliation: WHO Collaborating Centre 309 for Oral Health Care Planning and Future Scenarios, and Department of Preventive and Restorative Dentistry, Radboud University Nijmegen Medical Centre, The Netherlands. w.vanpalenstein@dent.umcn.nl
authors.forename: W H
authors.initials: WH
authors.lastname: van Palenstein Helderman
authors.forename: M M
authors.initials: MM
authors.lastname: Kyaing
authors.forename: M T
authors.initials: MT
authors.lastname: Aung
authors.forename: W
authors.initials: W
authors.lastname: Soe
authors.forename: N A M
authors.initials: NA
authors.lastname: Rosema
authors.forename: G A
authors.initials: GA
authors.lastname: van der Weijden
authors.forename: M A
authors.initials: MA
authors.lastname: van 't Hof
mesh_terms: D002648:Child; D004396:Coloring Agents; D018592:Cross-Over Studies; D003773:Dental Plaque / Q000517:prevention & control* / Q000628:therapy; D003774:Dental Plaque Index; D004867:Equipment Design; D006801:Humans; D015203:Reproducibility of Results; D013499:Surface Properties; D013997:Time Factors; D014099:Toothbrushing / Q000295:instrumentation* / Q000379:methods
chemical_list: D004396:Coloring Agents