In vitro antidrepanocytary actvity (anti-sickle cell anemia) of some congolese plants.
Thirty aqueous and ethanolic extracts from 13 congolese plants were evaluated for their antidrepanocytary activity. Twelve of these plants, Alchornea cordifolia, Afromomum albo violaceum, Annona senegalensis, Cymbopogon densiflorus, Bridelia ferruginea, Ceiba pentandra, Morinda lucida, Hymenocardia acida, Coleus kilimandcharis, Dacryodes edulis, Caloncoba welwithsii, and Vinga unguiculata exhibited significant activities, thus, supporting the claims of the traditional healers and suggesting a possible correlation between the chemical composition of these plants and their uses in traditional medicine.
Mpiana
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PT
Département de Chimie, Université de Kinshasa, Kinshasa XI, R. D. Congo. ptmpiana@yahoo.fr
Tshibangu
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DS
Shetonde
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OM
Ngbolua
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KN
D000755:Anemia, Sickle Cell / Q000188:drug therapy*; D000986:Antisickling Agents / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D003223:Congo; D004913:Erythrocytes, Abnormal / Q000187:drug effects*; D006801:Humans; D016488:Medicine, African Traditional; D008517:Phytotherapy; D024301:Plant Bark; D010936:Plant Extracts / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D018515:Plant Leaves; D018517:Plant Roots; D010946:Plants, Medicinal
D000986:Antisickling Agents; D010936:Plant Extracts