Clinical inquiries: When are antibiotics indicated for acute COPD exacerbations?
Antibiotics (including those given orally) reduce mortality and treatment failures for hospitalized patients with acute exacerbations of chronic obstructive pulmonary disease (COPD) (strength of recommendation [SOR]: A, based on systematic reviews). Antibiotics may be prescribed in the outpatient setting for those with severe exacerbations (SOR: C, based on expert opinion).
Balser
Emily
E
Valley Medical Center Family Medicine Residency, Renton, WA, USA.
Neher
Jon O
JO
Safranek
Sarah
S
Taraday
Julie
J
D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D001993:Bronchodilator Agents / Q000627:therapeutic use; D018849:Controlled Clinical Trials as Topic; D019317:Evidence-Based Medicine; D006801:Humans; D017410:Practice Guidelines as Topic; D029424:Pulmonary Disease, Chronic Obstructive / Q000188:drug therapy* / Q000517:prevention & control; D055502:Secondary Prevention; D012720:Severity of Illness Index; D016896:Treatment Outcome
D000900:Anti-Bacterial Agents; D001993:Bronchodilator Agents