title: A randomized trial of local anesthesia with intravenous sedation vs general anesthesia for the vaginal correction of pelvic organ prolapse.
abstract: The purpose of this study is to compare the feasibility of local anesthesia with IV sedation versus general anesthesia for vaginal correction of pelvic organ prolapse. Patients with pelvic organ prolapse who were scheduled for an anterior or posterior colporrhaphy, or an obliterative procedure, and who did not have a contraindication or preference to type of anesthesia were randomized to one of the two anesthesia groups. Nineteen patients were randomized to the general group and 21 patients were randomized to the local group. Mean operating room, anesthesia, and surgical time were similar in each group, and 10 patients in the local group bypassed the recovery room. Requests and doses of antiemetics, postoperative verbal numerical pain scores and length of hospital stay were similar between the two groups. Mean recovery room and total hospital costs were significantly lower in the local group. Local anesthesia with IV sedation is a feasible alternative for vaginal surgery to correct pelvic organ prolapse.
authors.affiliation: Division of Urogynecology and Reconstructive Pelvic Surgery, Good Samaritan Hospital, Cincinnati, OH 45220, USA. Jsegal@sbhcs.com
authors.forename: J L
authors.initials: JL
authors.lastname: Segal
authors.forename: G
authors.initials: G
authors.lastname: Owens
authors.forename: W A
authors.initials: WA
authors.lastname: Silva
authors.forename: S D
authors.initials: SD
authors.lastname: Kleeman
authors.forename: R
authors.initials: R
authors.lastname: Pauls
authors.forename: M M
authors.initials: MM
authors.lastname: Karram
mesh_terms: D000368:Aged; D000700:Analgesics / Q000008:administration & dosage; D000768:Anesthesia, General / Q000191:economics; D000779:Anesthetics, Local / Q000191:economics; D000932:Antiemetics / Q000008:administration & dosage; D005260:Female; D006801:Humans; D006993:Hypnotics and Sedatives / Q000008:administration & dosage*; D007275:Injections, Intravenous; D007902:Length of Stay / Q000191:economics / Q000706:statistics & numerical data; D008875:Middle Aged; D009873:Operating Rooms / Q000706:statistics & numerical data; D010149:Postoperative Pain / Q000209:etiology*; D020250:Postoperative Nausea and Vomiting / Q000209:etiology; D011184:Postoperative Period; D011997:Recovery Room / Q000706:statistics & numerical data; D014596:Uterine Prolapse / Q000601:surgery*; D014621:Vagina / Q000601:surgery*
chemical_list: D000700:Analgesics; D000779:Anesthetics, Local; D000932:Antiemetics; D006993:Hypnotics and Sedatives