title: [Screening method for the determination of 199 pesticides in agricultural products by gas chromatography/ion trap mass spectrometry (GC/MS/MS)].
abstract: A screening method is described for determining 200 pesticides, except dimethipin, divided into four groups by means of gas chromatography/tandem mass spectrometry (GC/MS/MS) using an ion trap mass spectrometer equipped with automated gain control (AGC). The quantitation limit for 194 pesticides was 0.01 mg/kg on a crop basis, except for allidochlor, dimethoate, hexythiazox, methamidophos and triadimenol. The calibration curve of each pesticide was linear in the range of 0.04-5.0 microg/mL. One hundred and ninety-nine pesticides were added to matrix of potato, spinach, cabbage, apple, orange, soybean and unpolished rice at twice the limits of quantitation. The recoveries of 194 pesticides from all crops were satisfactory (50-150%) for screening purposes. Although some pesticides in apple and orange were not determined by selected ion monitoring (SIM) analysis at the limits of quantitation, all of them were identified by ion-trap GC/MS/MS at the same concentration. Thus, the ion trap GC/MS/MS technique is useful for the screening of residual pesticides present at low levels in agricultural products.
authors.affiliation: Kobe Quarantine Station, Center for Inspection of Imported Foods and Infectious Diseases: 1-1, Toyahama-cho, Hyogo-ku, Kobe 652-0866, Japan.
authors.forename: Yoshichika
authors.initials: Y
authors.lastname: Hirahara
authors.forename: Mika
authors.initials: M
authors.lastname: Kimura
authors.forename: Tomoko
authors.initials: T
authors.lastname: Inoue
authors.forename: Seiji
authors.initials: S
authors.lastname: Uchikawa
authors.forename: Shoji
authors.initials: S
authors.lastname: Otani
authors.forename: Hideaki
authors.initials: H
authors.lastname: Hirose
authors.forename: Sosuke
authors.initials: S
authors.lastname: Suzuki
authors.forename: Yukinori
authors.initials: Y
authors.lastname: Uchida
mesh_terms: D001937:Brassica / Q000737:chemistry; D032084:Citrus sinensis / Q000737:chemistry; D018556:Crops, Agricultural / Q000737:chemistry*; D005504:Food Analysis / Q000379:methods; D008401:Gas Chromatography-Mass Spectrometry / Q000379:methods*; D027845:Malus / Q000737:chemistry; D012275:Oryza / Q000737:chemistry; D010573:Pesticide Residues / Q000032:analysis*; D011198:Solanum tuberosum / Q000737:chemistry; D013025:Glycine max / Q000737:chemistry; D018724:Spinacia oleracea / Q000737:chemistry; D053719:Tandem Mass Spectrometry / Q000379:methods*
chemical_list: D010573:Pesticide Residues