title: Emergent fetal intracardiac transfusion for thrombocytopenia and acute hypovolemia due to cordocentesis-associated hemorrhage in parvovirus-induced hydrops.
abstract: OBJECTIVE
  To demonstrate the utility of fetal intracardiac transfusion to correct acute fetal hypovolemia and thrombocytopenia in fetal Parvovirus infection.
  
  
  METHODS
  Intracardiac transfusion in a 19-week gestation was indicated due to cordocentesis-associated hemorrhage.
  
  
  RESULTS
  Intracardiac transfusion resulted in correction of acute bradycardia, anemia and thrombocytopenia and persistent umbilical cord hemorrhage following attempted intravascular transfusion.
  
  
  CONCLUSIONS
  This case illustrates the importance of anticipating both thrombocytopenia and anemia in fetal Parvovirus infection and how an intracardiac approach can be employed in the setting of acute, life-threatening hemorrhage.
authors.affiliation: Perinatal Center, St Luke's Hospital and Health Network, Bethlehem, PA 18015, USA. apsarno@earthlink.net
authors.forename: Albert P
authors.initials: AP
authors.lastname: Sarno
authors.forename: Steven J
authors.initials: SJ
authors.lastname: Feinstein
authors.forename: Joseph G
authors.initials: JG
authors.lastname: Bell
authors.forename: Reshma
authors.initials: R
authors.lastname: Parikh
authors.forename: Karen
authors.initials: K
authors.lastname: Papazian
mesh_terms: D000328:Adult; D001805:Blood Transfusion, Intrauterine / Q000379:methods*; D017218:Cordocentesis / Q000009:adverse effects*; D004632:Emergency Medical Services; D005260:Female; D005865:Gestational Age; D006470:Hemorrhage / Q000209:etiology*; D006801:Humans; D015160:Hydrops Fetalis / Q000821:virology*; D020896:Hypovolemia / Q000209:etiology / Q000628:therapy*; D050498:Live Birth; D010322:Parvoviridae Infections / Q000150:complications* / Q000821:virology; D016732:Parvovirus B19, Human; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000821:virology*; D013921:Thrombocytopenia / Q000209:etiology / Q000628:therapy*