Comparative antibacterial activity of polymeric 3-alkylpyridinium salts isolated from the Mediterranean sponge Reniera sarai and their synthetic analogues.
Metabolites from marine sponges are considered a promising alternative to heavy metals in antifouling coatings. Water-soluble polymeric 3-alkylpyridinium salts and 14 related synthetic analogues showed considerable antibacterial activity against marine biofilm bacteria and may represent good candidates as natural biocides for marine technology applications.
Chelossi
Elisabetta
E
Institute of Marine Sciences, Section of Marine Technologies, CNR, Via De Marini 6, 16149 Genoa, Italy. chelossi@ge.cnr.it
Mancini
Ines
I
Sepcić
Kristina
K
Turk
Tom
T
Faimali
Marco
M
D000818:Animals; D000900:Anti-Bacterial Agents / Q000138:chemical synthesis / Q000302:isolation & purification* / Q000494:pharmacology; D018441:Biofilms / Q000187:drug effects; D011161:Porifera / Q000737:chemistry*; D011726:Pyridinium Compounds / Q000138:chemical synthesis / Q000302:isolation & purification* / Q000494:pharmacology; D014871:Water Microbiology
D000900:Anti-Bacterial Agents; D011726:Pyridinium Compounds