Elastic and rupture properties of porcine aortic tissue measured using inflation testing.
A new inflation test device was developed to study the mechanical properties of aortic tissue. The device was used to measure failure (rupture) strength and to determine the nonlinear, anisotropic elastic properties of porcine thoracic aorta. The tester was designed to stretch initially flat, circular tissue specimens to rupture under uniform biaxial loading. Water was chosen as the pressurizing fluid. Mechanical stretch and radius of curvature during inflation were measured optically in two orthogonal directions, and the Cauchy stress components were calculated from the deformation and the applied pressure. All porcine samples that ruptured successfully did so via a tear in the circumferential direction. Thus, the failure strength was taken to be the stress in the axial direction immediately prior to rupture. The mean failure strength was 1.75 MPa and mean axial stretch at failure was 1.52. These values agree well with published data for other arterial tissues. The nonlinearly elastic deformation behavior was modeled using a hyperelastic constitutive law of the type proposed by Holzapfel et al. [Holzapfel GA, Gasser TC, Ogden RW. J Elasticity 2000;61:1-48]. The results showed that the dominant directions of anisotropy in the porcine aortas were approximately 45 degrees to the axial and circumferential directions, and that the isotropic contribution to the constitutive model was insignificant.
Marra
Steven P
SP
Thayer School of Engineering, Dartmouth College, 8000 Cummings Hall, Hanover, NH, 03755-8000, USA. marra@dartmouth.edu
Kennedy
Francis E
FE
Kinkaid
Jeffrey N
JN
Fillinger
Mark F
MF
D000818:Animals; D016880:Anisotropy; D001013:Aorta, Thoracic / Q000502:physiology*; D003198:Computer Simulation; D004548:Elasticity; D004867:Equipment Design; D019544:Equipment Failure Analysis; D066298:In Vitro Techniques; D008365:Manometry / Q000295:instrumentation* / Q000379:methods; D008422:Materials Testing / Q000295:instrumentation* / Q000379:methods; D008955:Models, Cardiovascular; D010812:Physical Stimulation / Q000295:instrumentation* / Q000379:methods; D013314:Stress, Mechanical; D013552:Swine; D013718:Tensile Strength / Q000502:physiology