title: [Effectiveness of infliximab in patients with Behçet syndrome and severe uveoretinitis. Report of five cases].
abstract: The efficacy and safety of repeated administration of infliximab was evaluated in five patients (two men, three women) with Behçet syndrome accompanied by severe uveoretinitis. Ocular and extra ocular inflammation was suppressed in all patients during the observation period without any serious adverse reactions. The results in these patients suggests that TNF-á blockade is effective in patients with severe ocular Behçet syndrome.
authors.affiliation: Departamento de Oftalmología, Clínica Santa María, Santiago, Chile.
authors.forename: Guillermo
authors.initials: G
authors.lastname: Merino
authors.forename: Gonzalo
authors.initials: G
authors.lastname: Varas
authors.forename: Gonzalo
authors.initials: G
authors.lastname: Díaz
authors.forename: Miguel
authors.initials: M
authors.lastname: Gutiérrez
authors.forename: Loreto
authors.initials: L
authors.lastname: Massardo
authors.forename: Daniel
authors.initials: D
authors.lastname: Pacheco
authors.forename: Francisco
authors.initials: F
authors.lastname: Villarroel
authors.forename: Miguel
authors.initials: M
authors.lastname: Cuchacovich
mesh_terms: D000328:Adult; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use*; D000911:Antibodies, Monoclonal / Q000627:therapeutic use*; D001528:Behcet Syndrome / Q000175:diagnosis / Q000188:drug therapy*; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D000069285:Infliximab; D008297:Male; D008875:Middle Aged; D012173:Retinitis / Q000175:diagnosis / Q000188:drug therapy*; D014605:Uveitis / Q000175:diagnosis / Q000188:drug therapy*; D014792:Visual Acuity
chemical_list: D000893:Anti-Inflammatory Agents; D000911:Antibodies, Monoclonal; D000069285:Infliximab