title: Bilateral central crystalline corneal deposits four years after intacs for myopia.
abstract: OBJECTIVE
  To report a case of bilateral central crystalline keratopathy in the anterior stroma occurring 4 years after Intacs implantation.
  
  
  METHODS
  A 45-year-old woman underwent bilateral uncomplicated Intacs implantation for myopia. The postoperative course was uneventful. However, between 3 and 4 years after surgery, the patient developed central opacifications of the anterior stroma in both eyes, reducing best spectacle-corrected visual acuity.
  
  
  RESULTS
  Intacs were explanted. Confocal microscopy, electron microscopy of the explanted ring segments, and microbiology studies were performed. Opacities were still detectable at the slit-lamp microscope up to 8 months after explantation.
  
  
  CONCLUSIONS
  This is the first report on central corneal opacifications after Intacs implantation for myopia. The opacities could be the result of chronic metabolic stress or the beginning of lipid-like changes in another more central corneal localization.
authors.affiliation: Department of Ophthalmology, Inselspital, University of Bern, Switzerland.
authors.forename: Konstantinos
authors.initials: K
authors.lastname: Katsoulis
authors.forename: Gian-Marco
authors.initials: GM
authors.lastname: Sarra
authors.forename: Johannes C
authors.initials: JC
authors.lastname: Schittny
authors.forename: Beatrice E
authors.initials: BE
authors.lastname: Frueh
mesh_terms: D003318:Corneal Opacity / Q000209:etiology*; D003319:Corneal Stroma / Q000473:pathology / Q000601:surgery*; D020878:Device Removal; D005260:Female; D006801:Humans; D018613:Microscopy, Confocal; D008855:Microscopy, Electron, Scanning; D008875:Middle Aged; D009216:Myopia / Q000601:surgery*; D011183:Postoperative Complications; D019736:Prostheses and Implants / Q000009:adverse effects*; D019919:Prosthesis Implantation / Q000009:adverse effects*; D014792:Visual Acuity