Myeloproliferative disease in pregnancy and other management issues.
The goal of this review is to assess the current treatment and outcomes of special clinical situations in patients with myeloproliferative disease (MPD) such as pregnancy, major thrombotic and bleeding complications and surgical interventions. However, only a limited literature to support optimal management strategies is available. Many of the proposed strategies are the results of common sense or derive from the extrapolation of data from other studies not specifically designed to solve these problems. Therefore, practical recommendations to guide clinical decisions in these settings still remain largely empirical.
Barbui
Tiziano
T
Department of Hematology-Oncology, Ospedali Riuniti, Largo Barozzi 1, 24128 Bergamo, Italy. tbarbui@ospedaliriuniti.bergamo.it
Finazzi
Guido
G
D019468:Disease Management; D005260:Female; D006470:Hemorrhage; D006801:Humans; D009196:Myeloproliferative Disorders / Q000150:complications* / Q000628:therapy; D017410:Practice Guidelines as Topic; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000628:therapy*; D013927:Thrombosis