Processing facial emotions in adults with velo-cardio-facial syndrome: functional magnetic resonance imaging.
We studied the functional neuroanatomy of social behaviour in velo-cardio-facial syndrome (VCFS) using a facial emotional processing task and functional magnetic resonance imaging in adults with this syndrome and controls matched for age and IQ. The VCFS group had less activation in the right insula and frontal brain regions and more activation in occipital regions. Genetically determined abnormalities in pathways including those involved in emotional processing may underlie deficits in social cognition in people with VCFS.
van Amelsvoort
Therese
T
Department of Psychiatry, Academic Medical Centre, Amsterdam, The Netherlands. t.a.vanamelsvoort@amc.uva.nl
Schmitz
Nicole
N
Daly
Eileen
E
Deeley
Quinton
Q
Critchley
Hugo
H
Henry
Jayne
J
Robertson
Dene
D
Owen
Michael
M
Murphy
Kieran C
KC
Murphy
Declan G
DG
D000328:Adult; D004062:DiGeorge Syndrome / Q000523:psychology*; D004644:Emotions; D005149:Facial Expression; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D021641:Recognition, Psychology; D012565:Schizophrenic Psychology