Reactive arthritis: defined etiologies, emerging pathophysiology, and unresolved treatment.
ReA is unique in that it is one of the few disease states of which there is a known trigger. This insight into disease initiation has led to great advances in the pathophysiology. Despite this detailed knowledge, the proper treatment remains elusive. In the years to come it is possible that the specific treatment will be dictated by the triggering microbe.
Carter
John D
JD
Division of Rheumatology, University of South Florida, 12901 Bruce B. Downs Boulevard, MDC 81, Tampa, FL 33612, USA. jocarter@health.usf.edu
D000328:Adult; D000818:Animals; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D018501:Antirheumatic Agents / Q000627:therapeutic use*; D016918:Arthritis, Reactive / Q000188:drug therapy / Q000209:etiology / Q000276:immunology / Q000503:physiopathology; D001424:Bacterial Infections / Q000150:complications* / Q000382:microbiology; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008297:Male; D051379:Mice; D000091402:Prohibitins
D000900:Anti-Bacterial Agents; D018501:Antirheumatic Agents; C000717331:PHB2 protein, human; D000091402:Prohibitins