[The influence of photochemically activated 40% solution of levomecol ointment toward apoptosis in muscles of the rats posterior extremities in inflammatory-purulent complications of diabetes mellitus].
The influence of photochemically activated 40% solution of Levomecol ointment toward the tissue apoptosis while occurrence of ischemic complications of diabetes mellitus was studied in experiment on 184 adult mongrel white male rats weighted 250-310 g. While modelling of ischemic complications of diabetes mellitus there was revealed the cells apoptosis regulation in soft tissues of the affected lower extremities, causing worsening of the reparative processes course. Application of photochemically activated 40% solution of Levomecol ointment had promoted an effective correction of disorders in the cells apoptosis regulation. It substantiates the expediency of the method introduction into clinical practice.
Babenkov
H D
HD
Dolhopolov
V V
VV
Potiĭ
V V
VV
Shypilov
K V
KV
Peleshenko
O S
OS
D000818:Animals; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D017209:Apoptosis / Q000187:drug effects*; D002701:Chloramphenicol / Q000008:administration & dosage / Q000627:therapeutic use*; D003131:Combined Modality Therapy; D048909:Diabetes Complications; D004195:Disease Models, Animal; D004338:Drug Combinations; D007511:Ischemia / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology / Q000628:therapy*; D035002:Lower Extremity / Q000098:blood supply* / Q000473:pathology; D008297:Male; D018482:Muscle, Skeletal / Q000187:drug effects*; D009824:Ointments; D010778:Photochemotherapy / Q000379:methods*; D051381:Rats; D012996:Solutions; D014498:Uracil / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000627:therapeutic use
D000900:Anti-Bacterial Agents; D004338:Drug Combinations; D009824:Ointments; D012996:Solutions; C054376:levomecol; D014498:Uracil; D002701:Chloramphenicol