Therapeutic approach to FSGS in children.
Therapy of primary focal segmental glomerulosclerosis (FSGS) in children incorporates conservative management and immunosuppression regimens to control proteinuria and preserve kidney function. In long-term cohort studies in adults and children with primary FSGS, renal survival has been directly associated with degree of proteinuria control. This educational article reviews the current therapeutic approach toward children with primary FSGS.
Gipson
Debbie S
DS
Chapel Hill School of Medicine, University of North Carolina Kidney Center, University of North Carolina, 7012 Burnett-Womack Hall, CB#7155, Chapel Hill, NC, 27599-7155, USA. Debbie_Gipson@med.unc.edu
Gibson
Keisha
K
Gipson
Patrick E
PE
Watkins
Sandra
S
Moxey-Mims
Marva
M
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D018450:Disease Progression; D005923:Glomerulosclerosis, Focal Segmental / Q000188:drug therapy* / Q000235:genetics; D006801:Humans; D007165:Immunosuppression Therapy / Q000379:methods*; D007668:Kidney / Q000503:physiopathology; D011507:Proteinuria / Q000150:complications / Q000188:drug therapy; D051437:Renal Insufficiency / Q000209:etiology / Q000517:prevention & control