title: The colorectal malignant polyp: scoping a dilemma.
abstract: Colorectal adenomas containing invasive carcinoma represent the majority of early colorectal cancers. The malignant polyp carries a significant risk of lympho-haematic metastasis and mortality due to the penetration of cancerous cells into the submucosal layer. The therapeutic dilemma is whether to perform endoscopic or surgical resection. A thorough assessment of the endoscopic, histological and clinical variables is needed to unravel the best treatment for each patient. In particular, a unique staging of such lesions, based on certain histopathological features, has been deeply implicated in the therapeutic choice. Aim of this article is to review the main endoscopic, histological and clinical features of the malignant polyp in order to propose a systematic management of this lesion.
authors.affiliation: Gastroenterology and Digestive Endoscopy Unit, Nuovo Regina Margherita Hospital, Rome, Italy.
authors.forename: C
authors.initials: C
authors.lastname: Hassan
authors.forename: A
authors.initials: A
authors.lastname: Zullo
authors.forename: S
authors.initials: S
authors.lastname: Winn
authors.forename: A
authors.initials: A
authors.lastname: Eramo
authors.forename: S
authors.initials: S
authors.lastname: Tomao
authors.forename: F P
authors.initials: FP
authors.lastname: Rossini
authors.forename: S
authors.initials: S
authors.lastname: Morini
mesh_terms: D018256:Adenomatous Polyps / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D003111:Colonic Polyps / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D015179:Colorectal Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D004724:Endoscopy; D006801:Humans; D008953:Models, Anatomic; D009367:Neoplasm Staging