title: Transventricular hemispherotomy for surgical treatment of intractable epilepsy.
abstract: Surgical procedures for cerebral hemispherotomy may be broadly divided into those using a lateral and those using a vertical approach. However, careful study of surgical procedures using the lateral approach described in the literature shows differences in the approach to the ventricles. We discuss the application of transventricular hemispherotomy as a technique which provides relatively easy ventricular access for cerebral hemispherotomy. Transventricular hemispherotomy was successfully performed in a 36-year-old woman who was diagnosed with intractable epilepsy due to Sturge-Weber disease, and in a 25-year-old man who had developed intractable post-traumatic seizures after suffering cerebral contusion in a traffic accident as a child. These patients had no seizures or complications after surgery, and both patients have been weaned from antiepileptic drugs. The transventricular approach, as compared with other lateral approaches described in the literature, provides easy access to the ventricular cavity. Transventricular hemispherotomy proved to be a useful approach that allowed the following four common steps in cerebral hemispherotomy to be performed safely: (i) interruption of the internal capsule and corona radiata; (ii) resection of the medial temporal structures; (iii) transventricular corpus callosotomy; and (iv) disruption of the frontal horizontal fibers.
authors.affiliation: Department of Neurosurgery, Osaka City University, Graduate School of Medicine, 1-4-3 Asahi-machi, Abeno-ku, Osaka 545-8585, Japan. mitchy@med.osaka-cu.ac.jp
authors.forename: Michiharu
authors.initials: M
authors.lastname: Morino
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Shimizu
authors.forename: Takehiro
authors.initials: T
authors.lastname: Uda
authors.forename: Kentaro
authors.initials: K
authors.lastname: Naitoh
authors.forename: Shinichi
authors.initials: S
authors.lastname: Kawahara
authors.forename: Tomoya
authors.initials: T
authors.lastname: Ishiguro
authors.forename: Takeo
authors.initials: T
authors.lastname: Gotoh
authors.forename: Kenji
authors.initials: K
authors.lastname: Ohata
authors.forename: Mitsuhiro
authors.initials: M
authors.lastname: Hara
mesh_terms: D000328:Adult; D001930:Brain Injuries / Q000150:complications* / Q000601:surgery; D002552:Cerebral Ventricles / Q000601:surgery*; D003399:Craniotomy / Q000379:methods; D004827:Epilepsy / Q000209:etiology / Q000601:surgery*; D005260:Female; D038421:Hemispherectomy / Q000379:methods*; D006801:Humans; D008297:Male; D013341:Sturge-Weber Syndrome / Q000150:complications*; D016896:Treatment Outcome