title: Tacrolimus ointment 0.1% for the treatment of peristomal skin disease: 3 case reports.
abstract: Patients with stomas face a variety of problems, such as skin breakdown or ulceration at the peristomal site, that can complicate care. Topical steroids are frequently used to treat various inflammatory conditions that affect peristomal skin with good results, but chronic use can lead to undesirable side effects. Tacrolimus ointment 0.1%, a nonsteroidal immunosuppressant, could offer a more favorable alternative to topical steroids. We present 3 cases of peristomal skin disease that were successfully treated with tacrolimus ointment 0.1%.
authors.affiliation: Dartmouth Medical School, Hanover, New Hampshire, USA.
authors.forename: Gregory L
authors.initials: GL
authors.lastname: Wells
authors.forename: Joanne
authors.initials: J
authors.lastname: Brown
authors.forename: Wendy D
authors.initials: WD
authors.lastname: Manganiello
authors.forename: M Shane
authors.initials: MS
authors.lastname: Chapman
mesh_terms: D000287:Administration, Topical; D000368:Aged; D000369:Aged, 80 and over; D003110:Colonic Neoplasms / Q000601:surgery; D003872:Dermatitis / Q000188:drug therapy* / Q000209:etiology; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D008297:Male; D009824:Ointments; D054047:Surgical Stomas / Q000009:adverse effects; D016559:Tacrolimus / Q000008:administration & dosage / Q000627:therapeutic use*; D016896:Treatment Outcome; D001749:Urinary Bladder Neoplasms / Q000601:surgery
chemical_list: D007166:Immunosuppressive Agents; D009824:Ointments; D016559:Tacrolimus