siRNAs meet their match.
A new study addresses how to design highly specific small interfering RNAs (siRNAs) capable of distinguishing between similar variants of the same gene.
Potash
Jesse
J
D000690:Amyotrophic Lateral Sclerosis / Q000201:enzymology / Q000235:genetics* / Q000628:therapy; D015971:Gene Expression Regulation, Enzymologic / Q000187:drug effects / Q000235:genetics; D014644:Genetic Variation; D017354:Point Mutation; D012333:RNA, Messenger / Q000187:drug effects; D034741:RNA, Small Interfering / Q000235:genetics / Q000494:pharmacology / Q000627:therapeutic use; D013482:Superoxide Dismutase / Q000235:genetics*; D000072105:Superoxide Dismutase-1
D012333:RNA, Messenger; D034741:RNA, Small Interfering; D013482:Superoxide Dismutase; D000072105:Superoxide Dismutase-1