[Determination of 15 trace elements in antineoplastic traditional Chinese medicine by atomic absorption spectrometry].
Five kinds of antineoplastic traditional Chinese medicines including fufangtianxian capsule, xiaoaiping tablet, zhiling capsule, shenlian capsule and shenlinglan capsule were digested with HNO3-HCl mixed acid. The fifteen trace elements including calcium, magnesium, potassium, sodium, iron, zinc, manganese, cobalt, nickel, chromium, silver, copper, strontium, cadmium and lead in the above-mentioned drugs were determined by atomic adsorption spectrometry. The effects of the kinds of mixed acid, the ratio of HNO3 to HCl in the mixed acid, the volume of digesting solution and the digesting time were also investigated in detail. The results obtained show that the concentrations of Ca, Mg, K, Na, Fe, Zn, Mn, Co and Ni in the five kinds of antineoplastic Chinese traditional medicines are higher than those of other elements.
Liu
Yan-Ming
YM
College of Chemistry and Chemical Engineering, Xinyang Normal University, Xinyang 464000, China.
Wang
Hui
H
Han
Jin-Tu
JT
Lou
Zhi-Ge
ZG
Yue
Shi-Ping
SP
D000970:Antineoplastic Agents / Q000032:analysis* / Q000737:chemistry; D002118:Calcium / Q000032:analysis; D003035:Cobalt / Q000032:analysis; D003300:Copper / Q000032:analysis; D006851:Hydrochloric Acid / Q000737:chemistry; D008274:Magnesium / Q000032:analysis; D008345:Manganese / Q000032:analysis; D008516:Medicine, Chinese Traditional; D009532:Nickel / Q000032:analysis; D017942:Nitric Acid / Q000737:chemistry; D011188:Potassium / Q000032:analysis; D015203:Reproducibility of Results; D012964:Sodium / Q000032:analysis; D013054:Spectrophotometry, Atomic / Q000379:methods*; D013464:Sulfuric Acids / Q000737:chemistry; D014131:Trace Elements / Q000032:analysis*; D015032:Zinc / Q000032:analysis
D000970:Antineoplastic Agents; D013464:Sulfuric Acids; D014131:Trace Elements; D003035:Cobalt; D017942:Nitric Acid; D008345:Manganese; D003300:Copper; D009532:Nickel; D012964:Sodium; D008274:Magnesium; D015032:Zinc; C033158:sulfuric acid; D006851:Hydrochloric Acid; D011188:Potassium; D002118:Calcium