Electron transfer processes in DNA: mechanisms, biological relevance and applications in DNA analytics.
In principle, DNA-mediated charge transfer processes can be categorized as oxidative hole transfer and reductive electron transfer. With respect to the routes of DNA damage most of the past research has been focused on the investigation of oxidative hole transfer or transport. On the other hand, the transport or transfer of excess electrons has a large potential for biomedical applications, mainly for DNA chip technology.
Wagenknecht
Hans-Achim
HA
University of Regensburg, Institute for Organic Chemistry, D-93040, Regensburg, Germany. achim.wagenknecht@chemie.uni-regensburg.de
D020029:Base Pairing; D001483:Base Sequence; D004247:DNA / Q000737:chemistry* / Q000378:metabolism*; D004249:DNA Damage; D004579:Electron Transport; D004583:Electrons; D008958:Models, Molecular; D015394:Molecular Structure; D010084:Oxidation-Reduction
D004247:DNA