title: Pregnancy and birth outcomes in women with facioscapulohumeral muscular dystrophy.
abstract: Obstetric risk in facioscapulohumeral muscular dystrophy (FSHD) is not known. We surveyed 38 women with FSHD reporting 105 gestations and 78 live births. Review of medical records showed that pregnancy outcomes were generally favorable. The rates for low birth weight and total operative deliveries were statistically higher than the national rates in the general population. Worsening of FSHD was reported in 24% of gestations and did not usually resolve after delivery.
authors.affiliation: Department of Neurology, University of Rochester, 601 Elmwood Avenue, Box 673, Rochester, NY 14642, USA. Emma_Ciafaloni@urmc.rochester.edu
authors.forename: E
authors.initials: E
authors.lastname: Ciafaloni
authors.forename: E K
authors.initials: EK
authors.lastname: Pressman
authors.forename: A M
authors.initials: AM
authors.lastname: Loi
authors.forename: A M
authors.initials: AM
authors.lastname: Smirnow
authors.forename: D J
authors.initials: DJ
authors.lastname: Guntrum
authors.forename: N
authors.initials: N
authors.lastname: Dilek
authors.forename: R
authors.initials: R
authors.lastname: Tawil
mesh_terms: D000293:Adolescent; D000328:Adult; D001720:Birth Injuries / Q000453:epidemiology*; D002585:Cesarean Section / Q000706:statistics & numerical data; D015897:Comorbidity; D003430:Cross-Sectional Studies; D018450:Disease Progression; D005260:Female; D005316:Fetal Distress / Q000453:epidemiology; D006801:Humans; D007230:Infant, Low Birth Weight / Q000502:physiology; D007231:Infant, Newborn; D007239:Infections / Q000453:epidemiology; D018908:Muscle Weakness / Q000453:epidemiology; D020391:Muscular Dystrophy, Facioscapulohumeral / Q000453:epidemiology*; D011247:Pregnancy; D011248:Pregnancy Complications / Q000453:epidemiology*; D011795:Surveys and Questionnaires