title: [Leukemic infiltration of the optic nerve].
abstract: BACKGROUND
  We report a case of unilateral leukemic infiltration of the optic nerve caused by acute lymphoblastic leukemia.
  
  
  METHODS
  A 30-year-old woman with acute lymphoblastic leukemia beginning 3 months before was referred for left visual loss. The left fundus showed optic disc engorgement by infiltrating tumor, with numerous hemorrhages and exudates caused by optic nerve leukemic infiltration.
  
  
  CONCLUSIONS
  Optic nerve leukemic infiltration is considered as central nervous system damage with severe prognosis. Treatment is based upon systemic and intrathecal chemotherapy and central nervous system radiation.
authors.affiliation: Service d'Ophtalmologie, CHU de Fort de France, Hôpital Pierre Zobda-Quitman, BP 632, 97261 Fort de France Cedex. harold.merle@chu-fortdefrance.fr
authors.forename: H
authors.initials: H
authors.lastname: Merle
authors.forename: R
authors.initials: R
authors.lastname: Richer
authors.forename: A
authors.initials: A
authors.lastname: Donnio
authors.forename: A
authors.initials: A
authors.lastname: Jean-Charles
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D017254:Leukemic Infiltration; D009900:Optic Nerve / Q000473:pathology*; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000473:pathology*