title: Construction of an artificial heart pump performance test system.
abstract: A hydraulic loop, which simulates pressure/flow response of the human circulatory system, is needed to bench test the various versions of rotary left ventricular assist devices (LVADs). This article describes the design of such a loop and the simulated response of different physiological states, such as a healthy person in sleep, rest, and mild physical activity, and in different pathological states. The loop consists of: (1) pulsatile left and right cardiac simulators; (2) air/water tanks to model the venous and arterial compliances; (3) tygon tubes to model the venous, arterial, and other system flow resistances; and (4) a tuning clamp to model the variation in system resistance characteristics under different cardiac pressure/flow conditions. The simulated responses were compared to the data found in the literature to validate the loop performance prior to LVAD testing.
authors.affiliation: Virginia Artificial Heart Institute, University of Virginia, Charlottesville, VA, USA.
authors.forename: Yingjie
authors.initials: Y
authors.lastname: Liu
authors.forename: Paul
authors.initials: P
authors.lastname: Allaire
authors.forename: Yi
authors.initials: Y
authors.lastname: Wu
authors.forename: Houston
authors.initials: H
authors.lastname: Wood
authors.forename: Don
authors.initials: D
authors.lastname: Olsen
mesh_terms: D040761:Biomimetic Materials; D002320:Cardiovascular Physiological Phenomena; D004867:Equipment Design; D019544:Equipment Failure Analysis / Q000295:instrumentation* / Q000379:methods*; D006321:Heart / Q000503:physiopathology*; D006353:Heart-Assist Devices; D006801:Humans; D008955:Models, Cardiovascular