One new anthraquinone from marine Streptomyces sp. FX-58.
One new anthraquinone, 1,8-dihydroxy-2-ethyl-3-methylanthraquinone (1), together with two known compounds octadecanoic acid (2) and cholest-4-en-3-one (3) was isolated from marine actinomycete Streptomyces sp. FX-58. The structure of 1 was elucidated on the basis of spectroscopic methods, especially, the 2D-NMR spectral analysis. The cytotoxic activities of 1 were evaluated in vitro.
Huang
Yong-Fu
YF
School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, China.
Tian
Li
L
Fu
Hong-Wei
HW
Hua
Hui-Ming
HM
Pei
Yue-Hu
YH
D000880:Anthraquinones / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D019663:Chenopodiaceae / Q000382:microbiology*; D002681:China; D003603:Cytotoxins / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D005562:Formazans / Q000737:chemistry; D018922:HL-60 Cells; D006801:Humans; D020128:Inhibitory Concentration 50; D013058:Mass Spectrometry; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D013056:Spectrophotometry, Ultraviolet; D013302:Streptomyces / Q000737:chemistry*; D013778:Tetrazolium Salts / Q000737:chemistry
D000880:Anthraquinones; D003603:Cytotoxins; D005562:Formazans; D013778:Tetrazolium Salts; C079782:MTT formazan