A case report of langerhans histiocytosis presenting sequentially over a 21-year period with Letterer-Siwe disease, hand-Schuller-Christian disease and eosinophillic granuloma of bone.
Langerhans cell histiocytosis (LCH) is a very rare disorder, and usually considered a disease of childhood. The adult form of LCH is even rare, and in some case may be considered to represent delayed presentation of a pathologic process beginning in childhood. This case report highlights the range of presentations of LCH possible even in a single patient, and supports the contention that some adult LCH cases may be due to delayed presentation of childhood LCH.
Iupati
Douglas
D
Wellington Cancer Centre, Wellington Hospital, Pvt Bag 7902, New Zealand. Douglas.iupati@ccdhb.org.nz
Chander
Sarat
S
D000328:Adult; D004803:Eosinophilic Granuloma / Q000150:complications*; D005260:Female; D006646:Histiocytosis, Langerhans-Cell / Q000150:complications* / Q000175:diagnosis*; D006801:Humans; D008279:Magnetic Resonance Imaging; D014973:Xanthomatosis / Q000150:complications*