Coccidioidomycosis: a review and update.
Coccidioidomycosis occurs in arid and semi-arid regions of the New World from the western United States to Argentina. Highly endemic areas are present in the southwest United States. Coccidioides species live in the soil and produce pulmonary infection via airborne arthroconidia. The skin may be involved by dissemination of the infection, or by reactive eruptions, such as a generalized exanthem or erythema nodosum. Interstitial granulomatous dermatitis and Sweet's syndrome have recently been recognized as additional reactive signs of the infection. Coccidioidomycosis is a "great imitator" with protean manifestations. Cutaneous findings may be helpful clues in the diagnosis of this increasingly important disease.
DiCaudo
David J
DJ
Department of Dermatology and Pathology, Mayo Clinic, Scottsdale, Arizona 85259, USA. dicaudo.david@mayo.edu
D017088:AIDS-Related Opportunistic Infections / Q000453:epidemiology / Q000382:microbiology; D000818:Animals; D000935:Antifungal Agents / Q000627:therapeutic use; D003045:Coccidioides / Q000276:immunology / Q000502:physiology; D003047:Coccidioidomycosis / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology / Q000276:immunology / Q000473:pathology; D003881:Dermatomycoses / Q000453:epidemiology / Q000382:microbiology; D004198:Disease Susceptibility; D005260:Female; D006801:Humans; D007111:Immunity, Cellular; D008172:Lung Diseases, Fungal / Q000453:epidemiology / Q000382:microbiology; D008297:Male
D000935:Antifungal Agents