title: Lenticulostriate vasculopathy in twin-to-twin transfusion syndrome.
abstract: Intracranial pathology is a common and important complication in extremely low birth weight babies. Lenticulostriate vasculopathy (LSV) is an abnormal finding on cranial ultrasounds of sick babies and has been associated with congenital infection, chromosomal aberration and twin-to-twin transfusion. We describe a previously unreported situation of LSV being detected in both donor and recipient twin. This pair of monochorionic, diamniotic twins was admitted to the Neonatal Intensive Care Unit at 28 weeks of gestation. The mother underwent an emergency caesarean section because ultrasound and Doppler studies showed stage III twin-to-twin transfusion syndrome. The first twin weighed 998 g and second twin weighed 600 g. The first twin had an uneventful stay, whereas the second twin needed prolonged continuous positive airway pressure and indomethacin for patent ductus arteriosus. Both of them developed LSV. The clinical significance of this condition on the neuro-developmental outcome of a neonate has not yet been fully determined.
authors.affiliation: Department of Neonatology, The Neonatal Intensive Care Unit, The Townsville Hospital, Douglas, QLD, Australia. Yoga_Kandasamy@health.qld.gov.au
authors.forename: Y
authors.initials: Y
authors.lastname: Kandasamy
authors.forename: G
authors.initials: G
authors.lastname: Alcock
authors.forename: T H H G
authors.initials: TH
authors.lastname: Koh
mesh_terms: D020144:Basal Ganglia Cerebrovascular Disease / Q000000981:diagnostic imaging* / Q000209:etiology; D002317:Cardiovascular Agents / Q000627:therapeutic use; D045422:Continuous Positive Airway Pressure; D004374:Ductus Arteriosus, Patent / Q000188:drug therapy; D005260:Female; D005330:Fetofetal Transfusion / Q000150:complications*; D006801:Humans; D007213:Indomethacin / Q000627:therapeutic use; D007231:Infant, Newborn; D011247:Pregnancy; D013788:Thalamus / Q000000981:diagnostic imaging; D014430:Twins, Monozygotic; D014463:Ultrasonography
chemical_list: D002317:Cardiovascular Agents; D007213:Indomethacin