Dopamine-selective potentiometric responses by new ditopic sensory elements based on a hexahomotrioxacalix[3]arene.
New ditopic sensory elements 2 and 3 for catecholamines based on a hexahomotrioxacalix[3]arene, with a boronic acid substituent appended, were designed and synthesized. As an interesting mode of molecular recognition at membrane surfaces, the host, when incorporated into poly(vinyl chloride) (PVC) liquid membranes, displayed excellent potentiometric selectivity for dopamine over other catecholamines (noradrenaline and adrenaline) and inorganic cations (Na+, K+, and NH4+).
Saijo
Ryosuke
R
Graduate School of Pharmaceutical Sciences, Nagoya City University, Mizuho-ku, Nagoya 467-8603, Japan.
Tsunekawa
Saori
S
Murakami
Hiroyuki
H
Shirai
Naohiro
N
Ikeda
Shin-ichi
S
Odashima
Kazunori
K
D015374:Biosensing Techniques; D047250:Calixarenes / Q000737:chemistry*; D004298:Dopamine / Q000032:analysis*; D007202:Indicators and Reagents; D007700:Kinetics; D009682:Magnetic Resonance Spectroscopy; D008564:Membrane Potentials; D008567:Membranes, Artificial; D011143:Polyvinyl Chloride; D011199:Potentiometry
D007202:Indicators and Reagents; D008567:Membranes, Artificial; D047250:Calixarenes; D011143:Polyvinyl Chloride; D004298:Dopamine