title: A multiparametric brain and cord MR imaging study of a patient with Hirayama disease.
abstract: In this study, we used a multiparametric MR imaging approach to assess a patient with Hirayama disease (HD). We found that cervical cord damage extends beyond cord T2-visible lesions. We also showed an altered pattern of cortical activations during movements of clinically unaffected limbs. Whereas this study suggests a more widespread cord involvement in HD than seen on routine MR imaging, its cause remains unclear (vascular damage versus a primary lower motor neuron disease).
authors.affiliation: Neuroimaging Research Unit, Department. of Neurology, Scientific Institute and University Ospedale San Raffaele, Milan, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Gallo
authors.forename: M A
authors.initials: MA
authors.lastname: Rocca
authors.forename: P
authors.initials: P
authors.lastname: Tortorella
authors.forename: A
authors.initials: A
authors.lastname: Ammendola
authors.forename: G
authors.initials: G
authors.lastname: Tedeschi
authors.forename: M
authors.initials: M
authors.lastname: Filippi
mesh_terms: D001921:Brain / Q000503:physiopathology*; D005542:Forearm; D006225:Hand; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009133:Muscular Atrophy / Q000473:pathology* / Q000503:physiopathology*; D013116:Spinal Cord / Q000473:pathology*