Mucor circinelloides was identified by molecular methods as a cause of primary cutaneous zygomycosis.
A case of primary cutaneous zygomycosis caused by Mucor circinelloides is described. Histopathology showed typical hyphae along with chlamydospores. The isolate was identified by molecular and phenotypic methods. The utility of sequence analysis of the internal transcribed spacer region is highlighted; however, further studies are needed to assess species genetic heterogeneity.
Iwen
Peter C
PC
Department of Pathology and Microbiology, University of Nebraska Medical Center, 986495 Nebraska Medical Center, Omaha, NE 68198-6495, USA. piwen@unmc.edu
Sigler
Lynne
L
Noel
Rhonda K
RK
Freifeld
Alison G
AG
D000369:Aged, 80 and over; D004271:DNA, Fungal / Q000032:analysis / Q000302:isolation & purification; D003881:Dermatomycoses / Q000175:diagnosis / Q000382:microbiology*; D006801:Humans; D008297:Male; D008969:Molecular Sequence Data; D009089:Mucor / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification* / Q000648:ultrastructure; D009091:Mucormycosis / Q000175:diagnosis / Q000382:microbiology*; D016533:Mycological Typing Techniques; D010641:Phenotype; D016133:Polymerase Chain Reaction / Q000379:methods; D017422:Sequence Analysis, DNA
D004271:DNA, Fungal