Glucose intolerance and insulin resistance in extremely premature newborns, and implications for nutritional management.
Glucose intolerance and postnatal growth retardation are commonly seen in low-gestation newborns. In contrast to the nutrient compositions of parenteral and enteral nutrition, fetuses at equivalent gestational ages receive much more amino acids (protein) but less glucose and lipids through placental transfer.


CONCLUSIONS
A nutrition regime that simulates placental nutrient delivery would potentially minimize glucose intolerance and facilitate early attainment of normal growth velocity with normal body composition after preterm birth.
Yeung
Melinda Y
MY
Department of Pharmacy, The Children's Hospital at Westmead, New South Wales, Australia. melinday@chw.edu.au
D018149:Glucose Intolerance / Q000178:diet therapy* / Q000209:etiology; D006801:Humans; D007227:Infant Nutritional Physiological Phenomena; D007231:Infant, Newborn; D007234:Infant, Premature; D007333:Insulin Resistance / Q000502:physiology*; D007334:Insulin-Like Growth Factor I / Q000378:metabolism
D007334:Insulin-Like Growth Factor I