Molecular interactions of acute phase serum amyloid A: possible involvement in carcinogenesis.
Acute phase serum amyloid A (A-SAA) is a well-known marker of inflammation. The present review summarizes data on the regulation of A-SAA expression, signaling pathways which it is involved in, its effects, and possible influences on progression of malignant tumors.
Vlasova
M A
MA
Orekhovich Institute of Biomedical Chemistry, Russian Academy of Medical Sciences, Moscow, 119121, Russia.
Moshkovskii
S A
SA
D000818:Animals; D018450:Disease Progression; D015972:Gene Expression Regulation, Neoplastic; D006801:Humans; D050356:Lipid Metabolism; D020782:Matrix Metalloproteinases / Q000235:genetics / Q000378:metabolism; D008954:Models, Biological; D016328:NF-kappa B / Q000378:metabolism; D009369:Neoplasms / Q000235:genetics / Q000378:metabolism* / Q000473:pathology; D000685:Serum Amyloid A Protein / Q000235:genetics / Q000378:metabolism*
D016328:NF-kappa B; D000685:Serum Amyloid A Protein; D020782:Matrix Metalloproteinases