title: Tetramethylpyridiniumporphyrazines--a new class of G-quadruplex inducing and stabilising ligands.
abstract: 3,4-Tetramethylpyridiniumporphyrazines bind strongly and selectively to human telomeric G-quadruplex DNA, inducing the formation of an antiparallel quadruplex in a process that mimics molecular chaperones.
authors.affiliation: University Chemical Laboratory, Lensfield Road, Cambridge, UKCB2 1EW.
authors.forename: Diana P N
authors.initials: DP
authors.lastname: Gonçalves
authors.forename: Raphaël
authors.initials: R
authors.lastname: Rodriguez
authors.forename: Shankar
authors.initials: S
authors.lastname: Balasubramanian
authors.forename: Jeremy K M
authors.initials: JK
authors.lastname: Sanders
mesh_terms: D004247:DNA / Q000737:chemistry*; D054856:G-Quadruplexes; D008024:Ligands; D008745:Methylation; D015394:Molecular Structure; D011166:Porphyrins / Q000737:chemistry*; D011725:Pyridines / Q000737:chemistry*; D013057:Spectrum Analysis
chemical_list: D008024:Ligands; D011166:Porphyrins; D011725:Pyridines; D004247:DNA