A new citryl glycoside from Gastrodia elata and its inhibitory activity on GABA transaminase.
A new citryl glycoside, trimethylcitryl-beta-D-galactopyranoside (1) along with a known phenolic compound, gastrodigenin (2) have been isolated from the active fraction of the rhizomes of Gastrodia elata (Orchidaceae). Their structures were elucidated on the basis of spectroscopic data and chemical reaction. 1 inhibited GABA transaminase activity by 56.8% at the final concentration of 10 microg/ml.
Choi
Jung-Hyun
JH
Department of Biotechnology, Dongguk University.
Lee
Dong-Ung
DU
D000612:4-Aminobutyrate Transaminase / Q000037:antagonists & inhibitors*; D001592:Benzyl Alcohols / Q000737:chemistry / Q000494:pharmacology; D002236:Carbohydrate Conformation; D031668:Gastrodia / Q000737:chemistry*; D006027:Glycosides / Q000737:chemistry* / Q000494:pharmacology*; D027343:Rhizome / Q000737:chemistry
D001592:Benzyl Alcohols; D006027:Glycosides; C018966:4-hydroxybenzyl alcohol; D000612:4-Aminobutyrate Transaminase