title: Histological findings in cerebellar tonsils of patients with Chiari type I malformation.
abstract: OBJECTIVE
  Cerebellar tonsillectomy is often performed for relief of symptoms associated with Chiari type I malformation (CMI). Nonetheless, the idea of removing supposedly healthy central nervous tissue has been a source of concern for neurosurgeons. The aim of this paper is to determine the histological changes in the cerebellar tonsils of patients with a wide range of symptoms and conditions related to CMI.
  
  
  METHODS
  The cerebellar tonsils of 43 pediatric patients with CMI were sent to pathology for histological examination.
  
  
  CONCLUSIONS
  The cerebellar tonsils in a great majority of CMI patients can be abnormal. We suggest that the reported histological findings are secondary to injury and ischemia.
authors.affiliation: Division of Neurosurgery, Pediatric Neurosurgery, David Geffen UCLA School of Medicine, Los Angeles, CA 90095-7039, USA.
authors.forename: Francisco
authors.initials: F
authors.lastname: Pueyrredon
authors.forename: Natalia
authors.initials: N
authors.lastname: Spaho
authors.forename: Ivonne
authors.initials: I
authors.lastname: Arroyave
authors.forename: Harry
authors.initials: H
authors.lastname: Vinters
authors.forename: Jorge
authors.initials: J
authors.lastname: Lazareff
mesh_terms: D000293:Adolescent; D000328:Adult; D001139:Arnold-Chiari Malformation / Q000150:complications* / Q000473:pathology*; D002526:Cerebellar Diseases / Q000150:complications* / Q000473:pathology*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006652:Histological Techniques / Q000379:methods; D006801:Humans; D007223:Infant; D008297:Male