[Experimental study on the migration of vascular endothelial cells stimulated by IL-8].
To investigate the influence of different concentrations of IL-8 on the migration of vascular endothelial cells and find out the best IL-8 concentration, the transwell chamber motility assay and the scrape motility assay were applied to observe the migration of vascular endothelial cells induced by IL-8. The results demonstrated that the migration of vascular endothelial cells was increased significantly under different IL-8 concentrations, while the best effect occurred when IL-8 concentration was 100 ng/ml.
Zou
Minjun
M
Institute of Biomedical Engineering, West China Medical Center, Sichuan University, Chengdu 610041, China.
Liu
Xiaoheng
X
Li
Yi
Y
Lai
Yi
Y
D002465:Cell Movement / Q000187:drug effects*; D002478:Cells, Cultured; D004305:Dose-Response Relationship, Drug; D042783:Endothelial Cells / Q000166:cytology* / Q000187:drug effects; D004730:Endothelium, Vascular / Q000166:cytology; D006801:Humans; D016209:Interleukin-8 / Q000008:administration & dosage / Q000494:pharmacology*
D016209:Interleukin-8