title: Problems with up-front randomization in clinical trials.
authors.forename: Keith
authors.initials: K
authors.lastname: Wheatley
authors.forename: Robert K
authors.initials: RK
authors.lastname: Hills
authors.forename: Alan K
authors.initials: AK
authors.lastname: Burnett
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D007951:Leukemia, Myeloid / Q000401:mortality / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D018579:Patient Selection; D011897:Random Allocation; D016032:Randomized Controlled Trials as Topic / Q000379:methods*; D012107:Research Design; D033581:Stem Cell Transplantation; D016019:Survival Analysis