title: [Prophylactic intraaortic balloon pumping preserves left ventricular systolic function in acute anterior myocardial infarction without cardiogenic shock].
abstract: OBJECTIVE
  Left ventricular function and prognosis were evaluated in patients with acute myocardial infarction who underwent primary percutaneous coronary intervention supported by intraaortic balloon pumping.
  
  
  METHODS
  Fifty-eight consecutive patients with first acute myocardial infarction were treated between July 1999 and April 2006. Twenty-five had cardiogenic shock on admission, whereas 33 did not. Patients with anterior acute myocardial infarction without cardiogenic shock were divided into the prophylactic intraaortic balloon pumping group (Group 1; n=17) and the rescue intraaortic balloon pumping group (Group 2; n=9).
  
  
  RESULTS
  Thirty-day in-hospital mortality was 52% in cardiogenic shock patients, and 3% in non-shock patients. Baseline characteristics of non-shock anterior acute myocardial infarction were similar including Thrombolysis in Myocardial Infarction (TIMI) risk scores (5.1 and 5.0) in the two groups. However, average left ventricular ejection fraction in the convalescent stage was superior in Group 1 (48.7% vs. 37.8%, p = 0.03). Thirty-day in-hospital mortality was 0% in Group 1 and 11% in Group 2 (p = 0.34). Cox's hazard ratio in Group 2 to Group 1 was 2.38 (95% confidence intrerval; 0.84-11.1, p = 0.09) in terms of the subsequent major cardiac events.
  
  
  CONCLUSIONS
  Prophylactic use of intraaortic balloon pumping starting prior to primary percutaneous coronary intervention preserves the convalescent left ventricular systolic function in patients with high risk for anticipated cardiac events after anterior acute myocardial infarction without cardiogenic shock.
authors.affiliation: Division of Cardiology, Cardiovascular Center, Tsuchiya General Hospital, Hiroshima. tasakum@hotmail.com
authors.forename: Tomiharu
authors.initials: T
authors.lastname: Niida
authors.forename: Tadamichi
authors.initials: T
authors.lastname: Sakuma
authors.forename: Chikaaki
authors.initials: C
authors.lastname: Motoda
authors.forename: Takehito
authors.initials: T
authors.lastname: Tokuyama
authors.forename: Toshiharu
authors.initials: T
authors.lastname: Oka
authors.forename: Takenori
authors.initials: T
authors.lastname: Okada
authors.forename: Masaya
authors.initials: M
authors.lastname: Otsuka
authors.forename: Mamoru
authors.initials: M
authors.lastname: Toyofuku
authors.forename: Hidekazu
authors.initials: H
authors.lastname: Hirao
authors.forename: Yuji
authors.initials: Y
authors.lastname: Muraoka
authors.forename: Hironori
authors.initials: H
authors.lastname: Ueda
authors.forename: Yoshiko
authors.initials: Y
authors.lastname: Masaoka
authors.forename: Yasuhiko
authors.initials: Y
authors.lastname: Hayashi
mesh_terms: D000368:Aged; D015906:Angioplasty, Balloon, Coronary; D016757:Death, Sudden, Cardiac / Q000517:prevention & control; D006333:Heart Failure / Q000517:prevention & control; D006801:Humans; D007423:Intra-Aortic Balloon Pumping; D009203:Myocardial Infarction / Q000401:mortality / Q000503:physiopathology* / Q000517:prevention & control / Q000628:therapy*; D011379:Prognosis; D012189:Retrospective Studies; D012306:Risk; D055502:Secondary Prevention; D012770:Shock, Cardiogenic; D013599:Systole; D016277:Ventricular Function, Left