[The grounds of interspices difference in radiation-genetic effects of low-level radiation].
Radiation-genetic effects are characterized by large quantitative difference. After the low dose radiation appearance of mutation is the largest in Drosophila, substantially lower in mice, especially if irradiation was protracted, and practically absent in humans. As the possible grounds of this difference the author consider the existence of non-specific repair mechanism, which has arouse during evolution for diminution of different detrimental impacts, including ionizing radiation. The efficacy of such mechanism of natural protection is determined by the efficacy of the repair mechanisms, which is elevated in compliance with specific life span, which is of necessity for its maintenance. The evolution has led to maximal development of this mechanism in human beings, and it is proved in particular in prevention of the hereditary effect of low-level radiation.
Iarmonenko
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D000818:Animals; D001417:Background Radiation; D004260:DNA Repair / Q000235:genetics*; D004307:Dose-Response Relationship, Radiation; D004330:Drosophila / Q000235:genetics / Q000528:radiation effects; D006801:Humans; D051379:Mice; D009154:Mutation; D011831:Radiation Genetics; D011832:Radiation Injuries / Q000235:genetics*; D013045:Species Specificity