Presentation and clinical progression of pseudohypoparathyroidism with multi-hormone resistance and Albright hereditary osteodystrophy: a case series.
Anthropometric and biochemical features were retrospectively evaluated in 12 patients with pseudohypoparathyroidism, Albright hereditary osteodystrophy, and multi-hormone resistance. Hypothyroidism and subcutaneous calcifications were presenting features in younger children. Temporal trends in stimulatory hormone resistance included early thyroid-stimulating hormone elevation and progression from parathyroid hormone elevation to hyperphosphatemia and hypocalcemia.
Gelfand
Inessa M
IM
Department of Pediatrics, Division of Pediatric Endocrinology and Diabetology, James Whitcomb Riley Hospital for Children, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Eugster
Erica A
EA
DiMeglio
Linda A
LA
D002648:Child; D002675:Child, Preschool; D018450:Disease Progression; D005260:Female; D005359:Fibrous Dysplasia, Polyostotic / Q000097:blood* / Q000150:complications*; D006728:Hormones / Q000097:blood*; D006801:Humans; D007223:Infant; D008297:Male; D011547:Pseudohypoparathyroidism / Q000097:blood* / Q000150:complications*
D006728:Hormones