title: Primary appendiceal malignancy: a clinicopathologic study.
abstract: Primary appendiceal cancer is a rare neoplasm. We analyzed the clinicopathologic characteristics and clinical outcomes of patients with primary appendiceal cancer treated at Buddhist Tzu Chi General Hospital in Eastern Taiwan. We reviewed the medical records of patients who had appendectomy at our hospital over a 10-year period and studied those who had histologically proven malignant appendiceal neoplasms. We treated eight such patients: seven males and one female. Their median age was 66 years (range, 59-78 years). There were three mucinous adenocarcinomas, two colonic type adenocarcinomas, and three adenocarcinoids. No patient was diagnosed correctly before surgery, and five (62.5%) had a preoperative diagnosis of acute appendicitis. Operative procedures included right hemicolectomy or partial colectomy in four, debulking and right hemicolectomy in three, and appendectomy only in one. With a mean follow-up of 64 months (range, 3-132), patients with adenocarcinoid lesions had better prognosis than those with adenocarcinomas. The important prognostic factors of primary appendiceal cancer included histologic subtypes and the extent of dissemination. In our series, palliative resection for disseminated lesions with or without additional chemotherapy resulted in long-term survival.
authors.affiliation: Department of Surgery, Buddhist Tzu Chi University, Buddhist Tzu Chi General Hospital, Hualien, Taiwan.
authors.forename: Hwa-Tzong
authors.initials: HT
authors.lastname: Chen
authors.forename: Yeu-Tsu M
authors.initials: YT
authors.lastname: Lee
authors.forename: Andy Shaw-Bin
authors.initials: AS
authors.lastname: Chou
authors.forename: Yung-Kang
authors.initials: YK
authors.lastname: Wu
authors.forename: Wun-Yaw
authors.initials: WY
authors.lastname: Yin
authors.forename: Ming-Che
authors.initials: MC
authors.lastname: Lee
authors.forename: Yung-Hsiang
authors.initials: YH
authors.lastname: Hsu
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology; D002288:Adenocarcinoma, Mucinous / Q000473:pathology; D000368:Aged; D001063:Appendiceal Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D018282:Cystadenocarcinoma, Mucinous / Q000473:pathology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed