Sensitive measurement of ultratrace phenols in natural water by purge-and-trap with in situ acetylation coupled with gas chromatography-mass spectrometry.
A novel purge-and-trap method coupled with gas chromatography-mass spectrometry (GC-MS) is developed for the analysis of trace and ultratrace phenols based on their derivatization with acetic anhydride. Parameters affecting the extraction efficiency, such as purge temperature, concentration of sodium chloride, purge time, and volume of derivatization reagent, were investigated. The optimized conditions were addition of 150 microL acetic anhydride, purge time of 25 min at the purge temperature of 60 degrees C with 30% NaCl. The linear range was 0.2-100 microg L(-1) for phenols. The limits of detection (LODs) ranged from 0.08 to 0.15 microg L(-1) and the relative standard deviations (RSDs) for most of the phenols at the 10 microg L(-1) level were below 10%. Natural water samples collected from a pool were successfully analyzed using the proposed method. The recovery of spiked water samples was 72.9-84.2%.
Zhao
Ru-Song
RS
Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology, Ministry of Education, Department of Chemistry, Tsinghua University, Beijing, 100084, People's Republic of China. zrswangx@yahoo.com.cn
Cheng
Chuan-Ge
CG
Yuan
Jin-Peng
JP
Jiang
Ting
T
Wang
Xia
X
Lin
Jin-Ming
JM
D000107:Acetylation; D008401:Gas Chromatography-Mass Spectrometry / Q000379:methods* / Q000592:standards; D008722:Methods; D010636:Phenols / Q000032:analysis*; D012015:Reference Standards; D012680:Sensitivity and Specificity; D014873:Water Pollutants / Q000032:analysis*
D010636:Phenols; D014873:Water Pollutants