Lack of papillomavirus (HPV) in pterygia of a Brazilian sample.
OBJECTIVE
Because the influence of papillomavirus (HPV) in pterygium pathogenesis is controversial, the aim of this study was to identify whether it is present in the pterygia lesions in our region.


METHODS
Thirty-six patients with unilateral primary pterygia were submitted to excision of pterygia and a sample of normal conjunctiva. Tissues were submitted to polymerase chain reaction (PCR) evaluation for papillomavirus DNA detection.


RESULTS
We were unable to detect any HPV DNA in all studied specimens.


CONCLUSIONS
According to our results papillomarivus is not important for pterygium formation.
Schellini
Silvana Artioli
SA
Departamento de Oftalmologia, Otorrinolaringologia e Cirurgia de Cabeça e Pescoço, Faculdade de Medicina de Botucatu, Universidade Estadual Paulista Julio de Mesquita Filho, Botucatu, SP, Brasil. sartoli@fmb.unesp.br
Hoyama
Erika
E
Shiratori
Claudia Akemi
CA
Sakamoto
Regina Hitomi
RH
Candeias
João Manuel Grisi
JM
D000293:Adolescent; D000328:Adult; D000368:Aged; D001938:Brazil; D004279:DNA, Viral / Q000032:analysis*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D027383:Papillomaviridae / Q000302:isolation & purification*; D016133:Polymerase Chain Reaction; D011446:Prospective Studies; D011625:Pterygium / Q000601:surgery / Q000821:virology*
D004279:DNA, Viral