title: Otitis externa: Review and clinical update.
abstract: Otitis externa can take an acute or a chronic form, with the acute form affecting four in 1,000 persons annually and the chronic form affecting 3 to 5 percent of the population. Acute disease commonly results from bacterial (90 percent of cases) or fungal (10 percent of cases) overgrowth in an ear canal subjected to excess moisture or to local trauma. Chronic disease often is part of a more generalized dermatologic or allergic problem. Symptoms of early acute and most chronic disease include pruritus and local discomfort. If left untreated, acute disease can be followed by canal edema, discharge, and pain, and eventually by extra-canal manifestations. Topical application of an acidifying solution is usually adequate in treating early disease. An antimicrobial-containing ototopical is the preferred treatment for later-stage acute disease, and oral antibiotic therapy is reserved for advanced disease or those who are immunocompromised. Preventive measures reduce recurrences and typically involve minimizing ear canal moisture, trauma, or exposure to materials that incite local irritation or contact dermatitis.
authors.affiliation: Otolaryngology and Communicative Sciences Department, Medical University of South Carolina, 135 Rutledge Avenue, Charleston, SC 29425, USA.
authors.forename: J David
authors.initials: JD
authors.lastname: Osguthorpe
authors.forename: David R
authors.initials: DR
authors.lastname: Nielsen
mesh_terms: D019342:Acetic Acid / Q000008:administration & dosage / Q000627:therapeutic use; D000287:Administration, Topical; D000700:Analgesics / Q000627:therapeutic use; D000890:Anti-Infective Agents / Q000008:administration & dosage / Q000627:therapeutic use; D001558:Benzethonium / Q000008:administration & dosage / Q000627:therapeutic use; D003937:Diagnosis, Differential; D004338:Drug Combinations; D004342:Drug Hypersensitivity; D005122:Exudates and Transudates; D006801:Humans; D010032:Otitis Externa / Q000175:diagnosis* / Q000188:drug therapy* / Q000382:microbiology / Q000503:physiopathology; D011409:Propylene Glycols / Q000008:administration & dosage / Q000627:therapeutic use; D013256:Steroids / Q000008:administration & dosage / Q000627:therapeutic use
chemical_list: D000700:Analgesics; D000890:Anti-Infective Agents; D004338:Drug Combinations; D011409:Propylene Glycols; D013256:Steroids; C009679:VoSoL; D001558:Benzethonium; D019342:Acetic Acid