[Significance of urine dipstick test for occult blood in patients with diabetes mellitus].
OBJECTIVE
Hematuria is the usual urinary finding in patients with diabetic nephropathy. In this study, prevalence and significance of microhematuria in patients with diabetes mellitus were investigated.


METHODS
Five hundred and forty-two samples from outpatients, who consulted the Department of Diabetes and Metabolism, were categorized into 4 groups according to the results of the urine dipstick test. Group I :258 samples, urinary protein(u-P) 1+ and occult blood (OB) negative, group II: 95 samples: u-P 1+, OB 1+ approximately 3+, group III: 89 samples: u-P 2+ approximately 3+, OB negative, group IV 100 samples u-P 2+ approximately 3+, OB 1+ approximately 3+.


RESULTS
Serum concentrations of creatinine and highly sensitive CRP were both significantly higher in group II than in group I . Those parameters were also significantly higher in group IV than in group III.


CONCLUSIONS
These results indicate that a positive dipstick test for OB may occur in many patients with diabetes mellitus and suggest the progress of renal damage.
Ohisa
Noriko
N
Department of Clinical Laboratory, Tohoku University Hospital, Japan.
Yoshida
Katsumi
K
Kaku
Mitsuo
M
Ishigaki
Yasushi
Y
Oka
Yoshitomo
Y
Sato
Hiroshi
H
D003404:Creatinine / Q000097:blood; D048909:Diabetes Complications / Q000652:urine*; D003928:Diabetic Nephropathies / Q000175:diagnosis* / Q000453:epidemiology; D006417:Hematuria / Q000175:diagnosis* / Q000453:epidemiology; D006801:Humans; D009780:Occult Blood; D015995:Prevalence; D011507:Proteinuria / Q000175:diagnosis; D011934:Reagent Strips; D012680:Sensitivity and Specificity
D011934:Reagent Strips; D003404:Creatinine