Trends in the incidence of transient ischemic attacks, premorbid risk factors and the use of preventive treatments in the population of Dijon, France from 1985 to 2004.
BACKGROUND
We describe the epidemiological trends of transient ischemic attack (TIA) in a 20-year population-based pilot study.


METHODS
Trends in the incidence, risk factors and pre-TIA use of preventive treatments for TIA were observed from 1985 to 2004 according to the classic definition in the population of the city of Dijon, France (150,000 inhabitants).


RESULTS
The raw and standardized incidence of TIA were stable over time. We observed a significant increase in the mean age at TIA onset in women only. The prevalence of hypercholesterolemia and diastolic blood pressure > or =90 mm Hg among patients with TIA increased significantly. This contrasts with falls in smoking and in history of previous myocardial infarction.


CONCLUSIONS
The stability of classic TIA incidence, despite the rise in the proportion of elderly people, and the increase in the mean age at onset in women may be considered as a medical progress.
Bejot
Yannick
Y
Stroke Registry of Dijon, INSERM and Institut de Veille Sanitaire, Faculty of Medicine and University Hospital of Dijon, Dijon, France.
Rouaud
Olivier
O
Benatru
Isabelle
I
Durier
Jérôme
J
Caillier
Marie
M
Couvreur
Grégory
G
Fromont
Agnès
A
Falvo
Nicolas
N
Osseby
Guy-Victor
GV
Cottin
Yves
Y
Zeller
Marianne
M
Millerot
Emilie
E
Marie
Christine
C
Moreau
Thibault
T
Giroud
Maurice
M
D017677:Age Distribution; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D000925:Anticoagulants / Q000627:therapeutic use; D000959:Antihypertensive Agents / Q000627:therapeutic use; D001281:Atrial Fibrillation / Q000150:complications / Q000188:drug therapy / Q000453:epidemiology*; D004813:Epidemiology / Q000639:trends; D005260:Female; D005602:France / Q000453:epidemiology; D006801:Humans; D006937:Hypercholesterolemia / Q000150:complications / Q000453:epidemiology*; D006973:Hypertension / Q000150:complications / Q000188:drug therapy / Q000453:epidemiology*; D015994:Incidence; D002546:Ischemic Attack, Transient / Q000453:epidemiology* / Q000209:etiology* / Q000517:prevention & control; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000150:complications / Q000188:drug therapy / Q000453:epidemiology*; D010865:Pilot Projects; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use; D011159:Population Surveillance; D012042:Registries / Q000706:statistics & numerical data; D012307:Risk Factors; D017678:Sex Distribution; D012737:Sex Factors; D012907:Smoking / Q000009:adverse effects / Q000453:epidemiology*; D013997:Time Factors
D000925:Anticoagulants; D000959:Antihypertensive Agents; D010975:Platelet Aggregation Inhibitors