title: Palatal tremor in childhood: clinical and therapeutic considerations.
abstract: Palatal tremor (PT) is a rhythmic movement of the soft palate that often causes an ear click. PT can be symptomatic (SPT) or essential (EPT). The symptomatic form usually occurs in adults and the essential form mainly occurs in children. Several different treatments for EPT in children appear in the literature with variable reported efficacy. This report details four paediatric patients with EPT (three males, one female; mean age 6y 4mo [SD 6mo]; age at onset 6-7y) treated with piracetam (2-oxo-1-pyrrolidine acetamide). Piracetam was used to treat EPT because of its antimyoclonic properties. All children showed a good response to doses of 100 to 300mg/kg/day. EPT relapsed on withdrawal of piracetam and remitted on reintroduction. Piracetam's effect on EPT was sustained. It is concluded that piracetam is an effective drug for the treatment of EPT in children.
authors.affiliation: Department of Neuropediatrics, Hospital Sant Joan de Déu, Universitat de Barcelona, Barcelona, Spain. campistol@hsjdbcn.org
authors.forename: J
authors.initials: J
authors.lastname: Campistol-Plana
authors.forename: A
authors.initials: A
authors.lastname: Majumdar
authors.forename: E
authors.initials: E
authors.lastname: Fernández-Alvarez
mesh_terms: D002648:Child; D020329:Essential Tremor / Q000188:drug therapy*; D005260:Female; D006801:Humans; D008297:Male; D018696:Neuroprotective Agents / Q000627:therapeutic use*; D010160:Palate, Soft; D010889:Piracetam / Q000627:therapeutic use*; D016896:Treatment Outcome
chemical_list: D018696:Neuroprotective Agents; D010889:Piracetam