Risk factors for genital and anal warts in a prospective cohort of HIV-negative homosexual men: the HIM study.
OBJECTIVE
The objective of this study was to determine the prevalence, incidence, and risk factors for genital and anal warts in HIV-negative homosexual men in Sydney.


METHODS
The authors conducted a prospective cohort study. Participants were asked whether they had had genital and anal warts at each interview. Details of lifetime sexual contacts and sexual behaviors in the last 6 months were collected.


RESULTS
Among 1,427 men recruited, 8.9% and 19.6% reported a history of genital and anal warts at baseline, respectively. Incidence rates for genital and anal warts were 0.94 and 1.92 per 100 person-years, respectively. In multivariate analysis, both incident genital and anal warts were associated with younger age. In addition, incident genital warts was associated with insertive fingering (P trend = 0.018), whereas incident anal warts was associated with insertive fingering (P trend = 0.007) and insertive fisting (P trend = 0.039).


CONCLUSIONS
Anal warts were twice as common as genital warts. Fingering and other manual sexual practices may be an important transmission route for both.
Jin
Fengyi
F
National Centre in HIV Epidemiology and Clinical Research, University of New South Wales, Darlinghurst, New South Wales, Australia. jjin@nchecr.unsw.edu.au
Prestage
Garrett P
GP
Kippax
Susan C
SC
Pell
Catherine M
CM
Donovan
Basil
B
Templeton
David J
DJ
Kaldor
John M
JM
Grulich
Andrew E
AE
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D001004:Anus Diseases / Q000453:epidemiology* / Q000209:etiology / Q000517:prevention & control; D015331:Cohort Studies; D003218:Condylomata Acuminata / Q000453:epidemiology* / Q000209:etiology / Q000517:prevention & control; D015658:HIV Infections; D018451:Homosexuality, Male; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D009517:New South Wales / Q000453:epidemiology; D030361:Papillomavirus Infections / Q000453:epidemiology* / Q000209:etiology / Q000517:prevention & control; D011446:Prospective Studies; D012307:Risk Factors