title: Disease pathology: wasting energy fighting infection.
abstract: Drosophila melanogaster infected with Mycobacterium marinum suffer metabolic wasting similar to that seen in humans suffering from tuberculosis. This wasting is linked to insulin signaling and hastens host death.
authors.affiliation: Department of Entomology, Field of Genetics and Development, Cornell University, Ithaca, New York 15843, USA. BL89@cornell.edu
authors.forename: Brian P
authors.initials: BP
authors.lastname: Lazzaro
authors.forename: Madeline R
authors.initials: MR
authors.lastname: Galac
mesh_terms: D000818:Animals; D004331:Drosophila melanogaster / Q000382:microbiology; D004734:Energy Metabolism / Q000276:immunology / Q000502:physiology*; D006801:Humans; D007328:Insulin / Q000378:metabolism*; D019910:Mycobacterium marinum; D015398:Signal Transduction / Q000502:physiology*; D014376:Tuberculosis / Q000276:immunology / Q000503:physiopathology*; D015431:Weight Loss
chemical_list: D007328:Insulin