title: [Intestinal leishmaniasis and Sézary syndrome: endoscopic diagnosis].
abstract: Sézary syndrome is a non-Hodgkin's lymphoma of cutaneous origin that provokes severe cellular immunosuppression leading to greater susceptibility to opportunistic infections. We present the case of a male patient with a diagnosis of Sézary syndrome complicated by visceral leishmaniasis and Mycobacterium avium complex coinfection, with intestinal involvement of both pathogens -an exceptional finding in the absence of HIV infection. The diagnosis was confirmed by bone marrow biopsy and oral endoscopy with intestinal biopsy. Because of the severity of the infection and the failure of conventional treatment, miltefosine, a new antiparasitic agent still under investigation, was administered with favorable response. However the patient developed fatal pneumonia.
authors.affiliation: Servicio de Medicina del Aparato Digestivo. Hospital Universitario 12 de Octubre. Madrid. España. amasedo@yahoo.es
authors.forename: Angeles
authors.initials: A
authors.lastname: Masedo González
authors.forename: José María
authors.initials: JM
authors.lastname: Barbero Allende
authors.forename: Mercedes
authors.initials: M
authors.lastname: Pérez-Carreras
authors.forename: María
authors.initials: M
authors.lastname: Garrido
authors.forename: Manuel
authors.initials: M
authors.lastname: Lizasoain
authors.forename: José Antonio
authors.initials: JA
authors.lastname: Solís Herruzo
mesh_terms: D000328:Adult; D001706:Biopsy; D004386:Duodenum / Q000473:pathology; D016099:Endoscopy, Gastrointestinal; D017809:Fatal Outcome; D006801:Humans; D007410:Intestinal Diseases / Q000150:complications* / Q000175:diagnosis*; D007898:Leishmaniasis, Visceral / Q000150:complications* / Q000175:diagnosis*; D008297:Male; D015270:Mycobacterium avium-intracellulare Infection / Q000150:complications / Q000175:diagnosis; D009894:Opportunistic Infections / Q000150:complications* / Q000175:diagnosis*; D012751:Sezary Syndrome / Q000150:complications*