Post-neurosurgical meningitis due to multidrug-resistant Acinetobacter baumanii treated with intrathecal colistin: case report and review of the literature.
Intrathecal colistin (Polymxin E) is becoming an important option for the treatment of post-neurosurgical meningitis caused by multidrug resistant (MDR) Acinetobacter baumannii. We report a case of 28-year-old man who developed meningitis due to MDR A. baumannii associated with an external ventricular drain. The patient was cured using a 4-week course of intrathecal colistin 3.2 mg via external ventricular drain (EVD) daily without any serious side effects.
Al Shirawi
N
N
Department of Intensive Care Unit, King Abdulaziz Medical City-King Fahad National Guard Hospital, Riyadh, Saudi Arabia.
Memish
Z A
ZA
Cherfan
A
A
Al Shimemeri
A
A
D000151:Acinetobacter Infections / Q000188:drug therapy* / Q000209:etiology*; D040981:Acinetobacter baumannii / Q000187:drug effects; D000328:Adult; D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D003091:Colistin / Q000008:administration & dosage*; D006259:Craniocerebral Trauma / Q000601:surgery*; D024901:Drug Resistance, Multiple, Bacterial / Q000187:drug effects; D006801:Humans; D007278:Injections, Spinal; D008297:Male; D016920:Meningitis, Bacterial / Q000188:drug therapy* / Q000209:etiology*; D011183:Postoperative Complications / Q000188:drug therapy*
D000900:Anti-Bacterial Agents; D003091:Colistin