title: Fluorine-substituted hydroxyapatite scaffolds hydrothermally grown from aragonitic cuttlefish bones.
abstract: Porous hydroxyapatite scaffolds with different levels of fluorine substitution (46% and 85%) on the OH sites were produced via hydrothermal transformation of aragonitic cuttlefish bones at 200 degrees C and calcination at temperatures up to 1200 degrees C. The increasing level of F substitution reduces the kinetics and probably the yield of the reaction. The incorporation of F in the lattice of hydroxypatite caused a lowering of the unit cell volume due to reduction of the length of the a-axis. The crystallites formed were close in size to bone-like apatite and were orientated along the a-axis rather than the c-axis. There was evidence of AB-type carbonated apatite.
authors.affiliation: Department of Ceramics and Glass Engineering, University of Aveiro, CICECO, 3810-193 Aveiro, Portugal.
authors.forename: S
authors.initials: S
authors.lastname: Kannan
authors.forename: J H G
authors.initials: JH
authors.lastname: Rocha
authors.forename: S
authors.initials: S
authors.lastname: Agathopoulos
authors.forename: J M F
authors.initials: JM
authors.lastname: Ferreira
mesh_terms: D000818:Animals; D001031:Apatites / Q000737:chemistry*; D001672:Biocompatible Materials; D001842:Bone and Bones / Q000378:metabolism; D002119:Calcium Carbonate / Q000737:chemistry*; D003460:Crystallization; D049832:Decapodiformes; D017886:Durapatite / Q000737:chemistry*; D005461:Fluorine / Q000494:pharmacology*; D007700:Kinetics; D008422:Materials Testing; D008956:Models, Chemical; D017550:Spectroscopy, Fourier Transform Infrared; D013997:Time Factors; D014961:X-Ray Diffraction
chemical_list: D001031:Apatites; D001672:Biocompatible Materials; D005461:Fluorine; D017886:Durapatite; D002119:Calcium Carbonate