Protective effects of adenosine A2A agonist during hemorrhagic shock: a simple intervention may result in a complex response.
Ramakers
Bart P
BP
Riksen
Niels P
NP
van der Hoeven
Johannes G
JG
Smits
Paul
P
Pickkers
Peter
P
D000241:Adenosine / Q000031:analogs & derivatives* / Q000494:pharmacology; D058908:Adenosine A2 Receptor Agonists; D000818:Animals; D001794:Blood Pressure / Q000187:drug effects; D004907:Erythrocyte Deformability / Q000187:drug effects; D006801:Humans; D007155:Immunologic Factors / Q000494:pharmacology; D007249:Inflammation / Q000209:etiology / Q000276:immunology / Q000517:prevention & control; D008171:Lung Diseases / Q000209:etiology / Q000517:prevention & control*; D010627:Phenethylamines / Q000494:pharmacology*; D051381:Rats; D015427:Reperfusion Injury / Q000209:etiology / Q000517:prevention & control*; D012771:Shock, Hemorrhagic / Q000097:blood / Q000150:complications* / Q000503:physiopathology; D012774:Shock, Traumatic / Q000097:blood / Q000150:complications* / Q000503:physiopathology; D013997:Time Factors; D051197:Toll-Like Receptor 4 / Q000187:drug effects; D014665:Vasodilator Agents / Q000494:pharmacology*
D058908:Adenosine A2 Receptor Agonists; D007155:Immunologic Factors; D010627:Phenethylamines; C495345:TLR4 protein, human; D051197:Toll-Like Receptor 4; D014665:Vasodilator Agents; C061282:2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine; D000241:Adenosine