title: Adhesion proteins of Mycoplasma pneumoniae.
abstract: Mycoplasmas are unique cell wall deficient, cholesterol requiring, highly pleomorphic bacteria that possess very small genome. M. pneumoniae is an important human pathogen that possesses specialized tip organelle to mediate cytadherence. It is a complex multifactorial process requiring a group of mycoplasma proteins such as P1, P30, P116 and HMW1-3. Expression of major mycoplasma adhesin proteins in heterologous expression systems provides an opportunity to study the role(s) of these proteins in pathogenicity and helps to develop diagnostic reagents. In this review we highlight the role(s) of various cytadhesin proteins of M. pneumoniae.
authors.affiliation: Department of Microbiology, All India institute of medical Sciences, New Delhi, India. rc123@hotmail.com
authors.forename: Rama
authors.initials: R
authors.lastname: Chaudhry
authors.forename: Avanish Kumar
authors.initials: AK
authors.lastname: Varshney
authors.forename: Pawan
authors.initials: P
authors.lastname: Malhotra
mesh_terms: D018829:Adhesins, Bacterial / Q000737:chemistry / Q000235:genetics / Q000502:physiology*; D016680:Genome, Bacterial; D006801:Humans; D009177:Mycoplasma pneumoniae / Q000235:genetics / Q000472:pathogenicity*; D011019:Pneumonia, Mycoplasma / Q000175:diagnosis / Q000382:microbiology
chemical_list: D018829:Adhesins, Bacterial