title: Environment-sensitive fluorophore emitting in protic environments.
abstract: The unusual fluorescence properties of 8-methoxy-4-methyl-2H-benzo[g]chromen-2-one (1) are described. The fluorophore 1 is almost nonfluorescent in aprotic solvent (e.g., fluorescence quantum yield Phi(f) < 0.0003 in n-hexane), whereas it strongly fluoresces at long wavelengths (>450 nm) in protic solvent (e.g., Phi(f) = 0.21 in methanol). The fluorophore 1 also shows good applicability in developing a new fluorogenic (fluorescent "off-on") sensor. [structure: see text]
authors.affiliation: Graduate School of Pharmaceutical Sciences, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan. seiichi@mol.f.u-tokyo.ac.jp
authors.forename: Seiichi
authors.initials: S
authors.lastname: Uchiyama
authors.forename: Kazuyuki
authors.initials: K
authors.lastname: Takehira
authors.forename: Toshitada
authors.initials: T
authors.lastname: Yoshihara
authors.forename: Seiji
authors.initials: S
authors.lastname: Tobita
authors.forename: Tomohiko
authors.initials: T
authors.lastname: Ohwada
mesh_terms: D055598:Chemical Phenomena; D002627:Chemistry, Physical; D002867:Chromones / Q000737:chemistry*; D005453:Fluorescence; D005456:Fluorescent Dyes / Q000138:chemical synthesis* / Q000737:chemistry; D006863:Hydrogen-Ion Concentration; D000432:Methanol / Q000737:chemistry; D011522:Protons; D012997:Solvents
chemical_list: C522317:8-methoxy-4-methyl-2H-benzo(g)chromen-2-one; D002867:Chromones; D005456:Fluorescent Dyes; D011522:Protons; D012997:Solvents; D000432:Methanol