A new tetracyclic triterpenoid from the leaves of Azadirachta indica.
A new tetracyclic triterpenoid zeeshanol [25,26,27-trinor-apotirucalla-(apoeupha)-6alpha-, 21-dihydroxy, 7alpha-acetoxy, 1,14,22-tri-en-3, 16-dione] (1) along with a known constituent desfurano-6alpha-hydroxyazadiradione (2) have been isolated from the methanolic extract of the leaves of Azadirachta indica. The structure and the relative configurations of 1 were determined by the spectroscopic method (1H- and 13C-NMR, IR, and MS) and 2D-NMR experiments.
Siddiqui
Bina S
BS
H.E.J. Research Institute of Chemistry, International Centre for Chemical Sciences, University of Karachi, Karachi-75270, Pakistan. bina@khi.comsats.net.pk
Afshan
Farhana
F
Sham-Sul-Arfeen
Gulzar
Tahsin
T
D031601:Azadirachta / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D015394:Molecular Structure; D010154:Pakistan; D010936:Plant Extracts / Q000737:chemistry; D018515:Plant Leaves / Q000737:chemistry*; D014315:Triterpenes / Q000737:chemistry* / Q000302:isolation & purification
D010936:Plant Extracts; D014315:Triterpenes; C517936:zeeshanol