title: Severe botulism after focal injection of botulinum toxin.
abstract: We report a 34-year-old woman who developed clinical botulism after the cosmetic use of an unapproved botulinum toxin type A. Electrophysiologic findings demonstrated complete denervation with complete electrical silence. She had a lengthy recovery but was able to ambulate by discharge.
authors.affiliation: Departments of Neurology, New Jersey Medical School of the University of Medicine and Dentistry of New Jersey, Newark, NJ 07101, USA. souayani@umdnj.edu
authors.forename: N
authors.initials: N
authors.lastname: Souayah
authors.forename: H
authors.initials: H
authors.lastname: Karim
authors.forename: S S
authors.initials: SS
authors.lastname: Kamin
authors.forename: J
authors.initials: J
authors.lastname: McArdle
authors.forename: S
authors.initials: S
authors.lastname: Marcus
mesh_terms: D000328:Adult; D001904:Botulinum Antitoxin / Q000627:therapeutic use; D019274:Botulinum Toxins, Type A / Q000008:administration & dosage / Q000506:poisoning*; D001906:Botulism / Q000139:chemically induced* / Q000503:physiopathology; D004305:Dose-Response Relationship, Drug; D062787:Drug Overdose / Q000503:physiopathology; D004576:Electromyography; D005260:Female; D006801:Humans; D020407:Internet; D008318:Malpractice; D018908:Muscle Weakness / Q000139:chemically induced / Q000175:diagnosis / Q000503:physiopathology; D018482:Muscle, Skeletal / Q000187:drug effects / Q000503:physiopathology; D009465:Neuromuscular Agents / Q000008:administration & dosage / Q000506:poisoning*; D009469:Neuromuscular Junction / Q000187:drug effects / Q000503:physiopathology; D010243:Paralysis / Q000139:chemically induced* / Q000503:physiopathology; D011782:Quadriplegia / Q000139:chemically induced / Q000503:physiopathology; D012121:Respiration, Artificial; D012131:Respiratory Insufficiency / Q000139:chemically induced / Q000503:physiopathology; D012651:Self Medication / Q000009:adverse effects*; D015595:Skin Aging / Q000187:drug effects
chemical_list: D001904:Botulinum Antitoxin; D009465:Neuromuscular Agents; D019274:Botulinum Toxins, Type A