title: Predicting the outcome of prostatectomy using noninvasive bladder pressure and urine flow measurements.
abstract: OBJECTIVE
  To determine whether categorisation of bladder outlet obstruction (BOO) using measurements of bladder pressure and urine flow obtained by a novel noninvasive medical device (the penile cuff test) improves prediction of outcome from endoscopic prostatectomy (TURP).
  
  
  METHODS
  A consecutive cohort of 208 men undergoing TURP following standard assessment in our institution was recruited, and 179 (86%) completed the protocol. Each subject underwent a penile cuff test prior to surgery; outcome was assessed by change in IPSS at 4 mo. The proportion of men with good outcome (>50% reduction in IPSS) was compared according to categorisation by noninvasive bladder pressure and urine flow measurements.
  
  
  RESULTS
  The cuff test was completed by 93% of men with 2% experiencing an adverse event. Men categorised as having BOO by the test (37% of total) had an 87% chance of a good outcome from TURP (p<0.01), whilst of those deemed not obstructed (19% of total) 56% experienced good outcome (p<0.01). For the remaining men not categorised in these two groups, 77% had good outcome, which was identical to the result of the cohort as a whole (77%, p=NS).
  
  
  CONCLUSIONS
  Urodynamic categorisation using measurements obtained by the noninvasive penile cuff test improves prediction of outcome for men with LUTS undergoing TURP. This finding together with the ease and acceptability of the test suggest its suitability for office-based clinical use to assist men and their physicians in the selection for surgical treatment for relief of LUTS.
authors.affiliation: Department of Urology, Freeman Hospital, Newcastle upon Tyne, UK.
authors.forename: Christopher
authors.initials: C
authors.lastname: Harding
authors.forename: Wendy
authors.initials: W
authors.lastname: Robson
authors.forename: Michael
authors.initials: M
authors.lastname: Drinnan
authors.forename: Mustafa
authors.initials: M
authors.lastname: Sajeel
authors.forename: Peter
authors.initials: P
authors.lastname: Ramsden
authors.forename: Clive
authors.initials: C
authors.lastname: Griffiths
authors.forename: Robert
authors.initials: R
authors.lastname: Pickard
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D011237:Predictive Value of Tests; D011312:Pressure; D011471:Prostatic Neoplasms / Q000601:surgery*; D012189:Retrospective Studies; D012212:Rheology / Q000379:methods; D020728:Transurethral Resection of Prostate / Q000009:adverse effects*; D016896:Treatment Outcome; D001743:Urinary Bladder / Q000503:physiopathology*; D014549:Urinary Incontinence / Q000175:diagnosis* / Q000209:etiology / Q000503:physiopathology; D014563:Urodynamics / Q000502:physiology*