title: Copper deficiency myeloneuropathy resembling B12 deficiency: partial resolution of MR imaging findings with copper supplementation.
abstract: Copper deficiency has been associated with a clinical syndrome, myeloneuropathy. Radiographic changes resembling B(12) deficiency in the cervical spinal cord have been described. We present a case of copper deficiency myeloneuropathy, with cervical MR imaging findings resembling B(12) deficiency, which partially reversed following copper supplementation. This is, to our knowledge, the first described case of radiographic improvement with copper supplementation.
authors.affiliation: Department of Neurology, Mayo Clinic Scottsdale, Scottsdale, AZ 85259, USA. goodman.brent@mayo.edu
authors.forename: B P
authors.initials: BP
authors.lastname: Goodman
authors.forename: B W
authors.initials: BW
authors.lastname: Chong
authors.forename: A C
authors.initials: AC
authors.lastname: Patel
authors.forename: G P
authors.initials: GP
authors.lastname: Fletcher
authors.forename: B E
authors.initials: BE
authors.lastname: Smith
mesh_terms: D003300:Copper / Q000172:deficiency* / Q000627:therapeutic use; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D013118:Spinal Cord Diseases / Q000175:diagnosis* / Q000188:drug therapy; D014806:Vitamin B 12 Deficiency / Q000175:diagnosis*
chemical_list: D003300:Copper