title: Lamivudine reverses severe acute hepatitis B and pancytopenia after renal transplantation: a case report.
abstract: Pancytopenia is rare after acute hepatitis B infection. The use of lamivudine in the treatment of acute hepatitis B-associated pancytopenia in renal transplant recipients has not been documented. Herein we reported a 21-year-old woman who was infected with acute hepatitis B 6 months after renal transplantation, a condition complicated by pancytopenia. Lamivudine reversed the acute hepatitis in 1 month and the pancytopenia after 3 months, without a change in renal function. Lamivudine was maintained for 2 years without a hepatitis flare-up after 4 years.
authors.affiliation: Division of Nephrology, Department of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.
authors.forename: Y-C
authors.initials: YC
authors.lastname: Wang
authors.forename: M-C
authors.initials: MC
authors.lastname: Kuo
authors.forename: C-C
authors.initials: CC
authors.lastname: Hung
authors.forename: S-J
authors.initials: SJ
authors.lastname: Hwang
authors.forename: J-C
authors.initials: JC
authors.lastname: Tsai
authors.forename: H-C
authors.initials: HC
authors.lastname: Chen
mesh_terms: D000328:Adult; D005260:Female; D006509:Hepatitis B / Q000188:drug therapy*; D006801:Humans; D007676:Kidney Failure, Chronic / Q000601:surgery; D016030:Kidney Transplantation / Q000009:adverse effects*; D019259:Lamivudine / Q000627:therapeutic use*; D008111:Liver Function Tests; D010198:Pancytopenia / Q000188:drug therapy* / Q000821:virology; D016896:Treatment Outcome
chemical_list: D019259:Lamivudine