title: Synthesis of loliolide, actinidiolide, dihydroactinidiolide, and aeginetolide via cerium enolate chemistry.
abstract: Loliolide, aeginetolide, actinidiolide, and dihydroactinidiolide were synthesized in racemic form from a single common intermediate, prepared through the 1,2 addition of the cerium enolate of ethyl acetate to 2,6,6-trimethylcylohexenone.
authors.affiliation: Firmenich, Princeton, New Jersey 08543, USA. kirk.eidman@firmenich.com
authors.forename: Kirk F
authors.initials: KF
authors.lastname: Eidman
authors.forename: Brian S
authors.initials: BS
authors.lastname: MacDougall
mesh_terms: D002338:Carotenoids / Q000138:chemical synthesis* / Q000737:chemistry; D002563:Cerium / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy
chemical_list: D002563:Cerium; D002338:Carotenoids