title: Color Doppler, power Doppler and B-flow ultrasound in the assessment of ICA stenosis: Comparison with 64-MD-CT angiography.
abstract: The purpose of this study is to investigate the diagnostic potential of color-coded Doppler sonography (CCDS), power-Doppler (PD) and B-flow ultrasound in assessing the degree of extracranial internal carotid artery (ICA) stenosis in comparison to CT-angiography (MD-CTA). Thirty-two consecutive patients referred for CTA with 41 ICA-stenoses were included in this prospective study. MD-CTA was performed using a 64 row scanner with a CTDIvol of 13.1 mGy/cm. In CTA, CCDS, PD and B-flow, the degree of stenosis was evaluated by the minimal intrastenotic diameter in comparison to the poststenotic diameter. Two radiologists performed a quantitative evaluation of the stenoses in consensus blinded to the results of ultrasound. These were correlated to CTA, CCDS, PD and B-flow, intraoperative findings and clinical follow-up. Grading of the stenoses in B-flow ultrasound outperformed the other techniques in terms of accuracy with a correlation coefficient to CTA of 0.88, while PD and CCDS measurements yield coefficients of 0.74 and 0.70. Bland-Altman analysis additionally shows a very little bias of the three US methods between 0.5 and 3.2 %. There is excellent correlation (coefficient 0.88, CI 0.77-0.93) with 64-MD-CTA and B-flow ultrasound in terms of accuracy for intrastenotic and poststenotic diameter. Duplex sonography is useful for screening purposes.
authors.affiliation: Department of Clinical Radiology, University of Munich-Grosshadern Campus, Marchioninistr. 15, 81377 Munich, Germany. clevert@web.de
authors.forename: D-A
authors.initials: DA
authors.lastname: Clevert
authors.forename: T
authors.initials: T
authors.lastname: Johnson
authors.forename: E M
authors.initials: EM
authors.lastname: Jung
authors.forename: D-A
authors.initials: DA
authors.lastname: Clevert
authors.forename: P M
authors.initials: PM
authors.lastname: Flach
authors.forename: T I
authors.initials: TI
authors.lastname: Strautz
authors.forename: G
authors.initials: G
authors.lastname: Ritter
authors.forename: M T
authors.initials: MT
authors.lastname: Gallegos
authors.forename: R
authors.initials: R
authors.lastname: Kubale
authors.forename: C
authors.initials: C
authors.lastname: Becker
authors.forename: M
authors.initials: M
authors.lastname: Reiser
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002343:Carotid Artery, Internal; D016893:Carotid Stenosis / Q000000981:diagnostic imaging*; D002533:Cerebral Angiography / Q000379:methods*; D003287:Contrast Media; D005260:Female; D006801:Humans; D007479:Iopamidol; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012044:Regression Analysis; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed; D018608:Ultrasonography, Doppler / Q000379:methods*; D018615:Ultrasonography, Doppler, Color
chemical_list: D003287:Contrast Media; D007479:Iopamidol