title: Novel diffusion-weighted magnetic resonance imaging findings in leptomeningeal carcinomatosis: a case report.
abstract: This report presents a rare case of leptomeningeal carcinomatosis initially presenting with mental impairment and rapidly progressing to coma without any history of malignancy. In addition to highlighting the diagnostic difficulties, the linear high signal intensity along the cortex on the diffusion-weighted imaging (DWI) sequence of magnetic resonance (MR) imaging was identified accidentally. High signal change in the corresponding areas was also noted on unenhanced fluid-attenuated inversion recovery (FLAIR) MR imaging, which may be a novel method of diagnosing leptomeningeal carcinomatosis, which should be studied further.
authors.affiliation: Department of Internal Medicine, Taipei Veterans General Hospital, Taiwan, ROC.
authors.forename: Y-F
authors.initials: YF
authors.lastname: Hu
authors.forename: F-C
authors.initials: FC
authors.lastname: Chang
authors.forename: H-H
authors.initials: HH
authors.lastname: Hu
authors.forename: L-C
authors.initials: LC
authors.lastname: Hsu
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis* / Q000473:pathology; D000368:Aged; D003937:Diagnosis, Differential; D038524:Diffusion Magnetic Resonance Imaging; D005260:Female; D006801:Humans; D008577:Meningeal Neoplasms / Q000175:diagnosis* / Q000473:pathology