title: Reboxetine induced erectile dysfunction and spontaneous ejaculation during defecation and micturition.
abstract: This is a case report of reboxetine induced erectile dysfunction, seminal emission and ejaculation during defecation and micturition. A 44 year old male who had been suffering from depression without any sexual dysfunction was put on venlafaxine XR treatment. Due to delayed ejaculation and occasional episodes of absence of ejaculation he was switched to reboxetine. At the second week of treatment he reported erectile dysfunction and premature ejaculation, and seminal emission and ejaculation during defecation and micturition occurred later at 8th week of treatment. After he was switched to sertraline 50 mg/day, his erectile dysfunction, premature and spontaneous ejaculation symptoms subsided in 2 weeks. Although reboxetine is reported to be free of sexual side effects, individual vulnerabilities to such unwanted effects should be considered, and sexual dysfunction should be assessed thoroughly during the treatment.
authors.affiliation: Uludag University Faculty of Medicine, Department of Psychiatry, Bursa, Turkey. ysivri@uludag.edu.tr
authors.forename: Enver Yusuf
authors.initials: EY
authors.lastname: Sivrioglu
authors.forename: Veli Cihat
authors.initials: VC
authors.lastname: Topaloglu
authors.forename: Asli
authors.initials: A
authors.lastname: Sarandol
authors.forename: Cengiz
authors.initials: C
authors.lastname: Akkaya
authors.forename: Salih Saygin
authors.initials: SS
authors.lastname: Eker
authors.forename: Selcuk
authors.initials: S
authors.lastname: Kirli
mesh_terms: D000328:Adult; D000928:Antidepressive Agents / Q000009:adverse effects*; D003672:Defecation / Q000187:drug effects*; D003865:Major Depressive Disorder / Q000188:drug therapy; D006801:Humans; D008297:Male; D009025:Morpholines / Q000009:adverse effects*; D000077593:Reboxetine; D019968:Sexual and Gender Disorders / Q000139:chemically induced*; D014554:Urination / Q000187:drug effects*
chemical_list: D000928:Antidepressive Agents; D009025:Morpholines; D000077593:Reboxetine