title: Sensitive measurement of ultratrace phenols in natural water by purge-and-trap with in situ acetylation coupled with gas chromatography-mass spectrometry.
abstract: A novel purge-and-trap method coupled with gas chromatography-mass spectrometry (GC-MS) is developed for the analysis of trace and ultratrace phenols based on their derivatization with acetic anhydride. Parameters affecting the extraction efficiency, such as purge temperature, concentration of sodium chloride, purge time, and volume of derivatization reagent, were investigated. The optimized conditions were addition of 150 microL acetic anhydride, purge time of 25 min at the purge temperature of 60 degrees C with 30% NaCl. The linear range was 0.2-100 microg L(-1) for phenols. The limits of detection (LODs) ranged from 0.08 to 0.15 microg L(-1) and the relative standard deviations (RSDs) for most of the phenols at the 10 microg L(-1) level were below 10%. Natural water samples collected from a pool were successfully analyzed using the proposed method. The recovery of spiked water samples was 72.9-84.2%.
authors.affiliation: Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology, Ministry of Education, Department of Chemistry, Tsinghua University, Beijing, 100084, People's Republic of China. zrswangx@yahoo.com.cn
authors.forename: Ru-Song
authors.initials: RS
authors.lastname: Zhao
authors.forename: Chuan-Ge
authors.initials: CG
authors.lastname: Cheng
authors.forename: Jin-Peng
authors.initials: JP
authors.lastname: Yuan
authors.forename: Ting
authors.initials: T
authors.lastname: Jiang
authors.forename: Xia
authors.initials: X
authors.lastname: Wang
authors.forename: Jin-Ming
authors.initials: JM
authors.lastname: Lin
mesh_terms: D000107:Acetylation; D008401:Gas Chromatography-Mass Spectrometry / Q000379:methods* / Q000592:standards; D008722:Methods; D010636:Phenols / Q000032:analysis*; D012015:Reference Standards; D012680:Sensitivity and Specificity; D014873:Water Pollutants / Q000032:analysis*
chemical_list: D010636:Phenols; D014873:Water Pollutants