Retroperitoneal lymph node dissection for high-risk stage I and stage IIA seminoma.
BACKGROUND
The clinical results of radiotherapy in low-stage seminoma are excellent with negligible early morbidity. However, in a long-term follow-up various complications may occur. On the other hand, experience in nonseminomas shows that surgical morbidity has decreased markedly after invention of a nerve-sparing technique. These issues served as a rationale for us to perform the primary retroperitoneal lymph node dissection (RPLND) in seminoma patients.


METHODS
Fourteen pure seminoma patients (10 high-risk stage I and four with clinical stage IIA) underwent nerve-sparing RPLND from September, 1997 to December, 2002.


RESULTS
Pathological evaluation revealed lymph node involvement in three out of 10 clinical stage I and in all four stage IIA cases. The patients' acceptance of the surgery was good. Minor intra- and early postoperative complications were observed in two cases. Antegrade ejaculation was preserved in all patients. No retroperitoneal or distant recurrences have been observed. All patients were free of disease with the mean follow-up period of 56 months.


CONCLUSIONS
The excellent results and minimum morbidity of nerve-sparing RPLND together with the increased concerns on late complications of radiotherapy may turn the preference of surgery in low-stage seminoma into the subject of future discussion.
Mezvrishvili
Zaza
Z
National Center of Urology, Tsinandali Str. 9, 0144, Tbilisi, Georgia. zazamezvrishvili@hotmail.com
Managadze
Laurent
L
D000328:Adult; D006801:Humans; D008197:Lymph Node Excision; D008297:Male; D009367:Neoplasm Staging; D012187:Retroperitoneal Space; D012307:Risk Factors; D018239:Seminoma / Q000473:pathology* / Q000601:surgery*; D013736:Testicular Neoplasms / Q000473:pathology* / Q000601:surgery*