[How participation in a clinical trial affects doctors' choice of treatment].
In a retrospective cohort study, the effects of participation in a company-sponsored clinical trial on asthma drug prescribing were investigated. Ten trial-conducting practices were compared with 165 control practices. Conducting the trial did not influence guideline adherence measured as the prevalence of inhaled corticosteroid use among users of inhaled beta2-agonists. However, participation in the trial led to an increased preference for sponsor's drugs.
Andersen
Morten
M
Syddansk Universitet, Forskningsenheden for Almen Praksis i Odense. mandersen@health.sdu.dk
Kragstrup
Jakob
J
Sørensen
Jens
J