title: What progress have we made with tinnitus? The Tonndorf Lecture 2005.
abstract: CONCLUSIONS
  The field of tinnitus research is vibrant and active. Prospects for progress are high, but would be optimized by the growth of inter-disciplinary collaborations.
  
  
  OBJECTIVE
  Tinnitus remains a source of urgent scientific investigation, and truly effective treatments continue to be elusive. The Tonndorf Lecture of the International Tinnitus Seminars represents an opportunity to reflect upon progress to date regarding tinnitus, and the actions needed to further that progress in future.
  
  
  METHODS
  Progress regarding tinnitus mechanisms is reviewed, with particular regard to the conceptual distinction between ignition sites for tinnitus, and the physiological mechanisms that then promote the tinnitus through the central auditory pathway. The current status of both the Jastreboff neurophysiological model and the psychological model of tinnitus is reviewed. Some concerns regarding each model are raised, and the need for models that integrate the insights of both perspectives is identified as urgent.
  
  
  RESULTS
  There are clear indications of progress in tinnitus, specifically regarding mechanisms, models and treatments. For knowledge to progress further, however, there is a pressing need for an inter-disciplinary approach to tinnitus, more involvement in teaching at a postgraduate level, and the development of experimental models of tinnitus that are both congruent with, and represent the complexity of, human experience of tinnitus.
authors.affiliation: Audiology, Addenbrooke's Hospital, Cambridge, UK. dmb29@cam.ac.uk
authors.forename: David M
authors.initials: DM
authors.lastname: Baguley
mesh_terms: D006801:Humans; D010036:Otolaryngology / Q000379:methods* / Q000639:trends*; D014012:Tinnitus / Q000503:physiopathology* / Q000628:therapy*