title: A convenient and efficient protocol for oxidative aromatization of Hantzsch 1,4-dihydropyridines using benzyltriphenylphosphonium peroxymonosulfate under almost neutral reaction conditions.
abstract: Oxidative aromatization of 4-alkyl or aryl and heterocyclic-substituted derivatives of Hantzsch 1,4-dihydropyridines to the corresponding pyridine derivatives has been studied using benzyltriphenylphosphonium peroxymonosulfate as an oxidant in the presence of BiCl(3) under nearly neutral reaction conditions at ambient temperature.
authors.affiliation: Department of Medicinal Chemistry, School of Pharmacy, Kermanshah University of Medical Sciences, Kermanshah 67168-67346, Islamic Republic of Iran. hadibi@kums.ac.ir
authors.forename: Hadi
authors.initials: H
authors.lastname: Adibi
authors.forename: Abdol Reza
authors.initials: AR
authors.lastname: Hajipour
mesh_terms: D000215:Acylation; D001593:Benzyl Compounds / Q000138:chemical synthesis* / Q000494:pharmacology*; D001729:Bismuth; D002855:Chromatography, Thin Layer; D003500:Cyclization; D004095:Dihydropyridines / Q000138:chemical synthesis*; D006571:Heterocyclic Compounds / Q000138:chemical synthesis; D007202:Indicators and Reagents; D009943:Organophosphorus Compounds / Q000138:chemical synthesis* / Q000494:pharmacology*; D010084:Oxidation-Reduction
chemical_list: D001593:Benzyl Compounds; D004095:Dihydropyridines; D006571:Heterocyclic Compounds; D007202:Indicators and Reagents; D009943:Organophosphorus Compounds; C518768:benzyltriphenylphosphonium peroxymonosulfate; C038806:1,4-dihydropyridine; D001729:Bismuth