Scedosporium infection in a tertiary care cancer center: a review of 25 cases from 1989-2006.
We reviewed the records of patients with cancer who had Scedosporium infection (due to Scedosporium apiospermum and Scedosporium prolificans in 21 and 4 patients, respectively). The incidence of Scedosporium infection increased from 0.82 cases per 100,000 patient-inpatient days (in 1993-1998) to 1.33 cases per 100,000 patient-inpatient days (in 1999-2005). Cases of S. prolificans infection occurred only after 2000. Dissemination occurred in 16 patients (64%). The 12-week mortality rates were 70% and 100% for S. apiospermum and S. prolificans infection, respectively.
Lamaris
Gregory A
GA
Department of Infectious Diseases, Infection Control and Employee Heath, The University of Texas M. D. Anderson Cancer Center, Houston, TX 77030, USA.
Chamilos
Georgios
G
Lewis
Russell E
RE
Safdar
Amar
A
Raad
Issam I
II
Kontoyiannis
Dimitrios P
DP
D000328:Adult; D000368:Aged; D002173:Cancer Care Facilities; D005260:Female; D006801:Humans; D016867:Immunocompromised Host; D015994:Incidence; D008297:Male; D008875:Middle Aged; D008271:Mycetoma / Q000453:epidemiology* / Q000209:etiology / Q000401:mortality; D009369:Neoplasms / Q000150:complications*; D021681:Scedosporium