title: Template-induced formation of heterobidentate ligands and their application in the asymmetric hydroformylation of styrene.
abstract: We report the template-induced formation of chelating heterobidentate ligands by the selective self-assembly of two different monodentate ligands on a rigid bis-zinc(II)-salphen template with two identical binding sites; these templated heterobidentate ligands induce much higher enantioselectivities (up to 72% ee) in the rhodium-catalyzed asymmetric hydroformylation of styrene than any of the corresponding homobidentate ligands or non-templated mixed ligand combinations (up to 13% ee).
authors.affiliation: Van't Hoff Institute for Molecular Sciences, University of Amsterdam, Nieuwe Achtergracht 166, 1018 WV Amsterdam, The Netherlands.
authors.forename: Mark
authors.initials: M
authors.lastname: Kuil
authors.forename: P Elsbeth
authors.initials: PE
authors.lastname: Goudriaan
authors.forename: Piet W N M
authors.initials: PW
authors.lastname: van Leeuwen
authors.forename: Joost N H
authors.initials: JN
authors.lastname: Reek