Efficient synthesis of a C-analogue of the immunogenic bacterial glycolipid BbGL2.
Synthesis of a C-analogue of bacterial glycolipid BbGL2 is reported using Grignard reaction of in situ generated beta-galactosyl iodide and subsequent olefin cross metathesis reaction of C-vinyl galactoside as key steps. [reaction: see text]
Kulkarni
Suvarn S
SS
Department of Chemistry, University of California-Davis, One Shields Avenue, Davis, CA 95616, USA.
Gervay-Hague
Jacquelyn
J
D025065:Borrelia burgdorferi / Q000737:chemistry*; D005697:Galactosides / Q000737:chemistry; D006017:Glycolipids / Q000138:chemical synthesis*; D007454:Iodides / Q000737:chemistry; D014753:Vinyl Compounds / Q000737:chemistry
C475930:1-O-palmitoyl-2-O-oleyl-3-O-galactopyranosyl-sn-glycerol; D005697:Galactosides; D006017:Glycolipids; D007454:Iodides; D014753:Vinyl Compounds