Neonatal death due to transposition in association with premature closure of the oval foramen.
We present a male infant, born at term, who collapsed and died at 30 minutes of age. Autopsy demonstrated concordant atrioventricular and discordant ventriculo-arterial connections with premature closure of the oval foramen, which bulged markedly into the left atrium. Premature closure of the oval foramen is rare in the setting of transposition. As far as we know, there have been only three previously reported cases.
Ashworth
Michael
M
Department of Paediatric Histopathology, Great Ormond Street Hospital, London, UK. ashwom@gosh.nhs.uk
Al Adnani
Mudher
M
Sebire
Neil J
NJ
D000015:Abnormalities, Multiple / Q000473:pathology; D017809:Fatal Outcome; D006343:Heart Septal Defects / Q000150:complications* / Q000473:pathology; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D014188:Transposition of Great Vessels / Q000150:complications* / Q000473:pathology