Lymphocytic interstitial pneumonia associated with common variable immunodeficiency resolved with intravenous immunoglobulins.
Lymphocytic interstitial pneumonia (LIP) is a rare form of interstitial lung disease. A few case reports have described an association with common variable immunodeficiency (CVID). Corticosteroids are usually used to treat symptomatic patients but their efficacy has never been studied in a controlled trial. We describe a patient with LIP and CVID who was treated monthly with intravenous immunoglobulins (IVIG) without steroids. The patient improved dramatically. We believe that, in selected cases of LIP and immunodeficiency, IVIG given monthly should be considered as the only treatment without adding steroids.
Arish
N
N
Department of Medicine C, Hadassah-Hebrew University Medical Center, Jerusalem, Israel 91120.
Eldor
R
R
Fellig
Y
Y
Bogot
N
N
Laxer
U
U
Izhar
U
U
Rokach
A
A
D000368:Aged; D017074:Common Variable Immunodeficiency / Q000000981:diagnostic imaging / Q000628:therapy*; D005260:Female; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000008:administration & dosage*; D017563:Lung Diseases, Interstitial / Q000000981:diagnostic imaging / Q000628:therapy*; D014057:Tomography, X-Ray Computed
D016756:Immunoglobulins, Intravenous