Desorption/ionization on porous silicon mass spectrometry (DIOS) of model cationized fatty acids.
Desorption/ionization on porous silicon (DIOS) is a very useful technique in the case of small molecular weight compounds, compared to the matrix-assisted laser desorption ionization (MALDI). This is because MALDI generates matrix-related ions that overlap with the mass range of interest. The aim of our work was to investigate the suitability of the DIOS technique in the case of fatty acids in negative ion mode. The analysis of the chosen fatty acid models, nonadecanoic acid (C(19)H(38)O(2)) and heneicosanoic acid (C(21)H(42)O(2)), gave rise to the observation of the deprotonated monomeric species and selective cationized multimeric species. This cation selectivity was further elucidated by complementary studies based on the addition of various metals such as Ag(I), Zn(II), Fe(II), and also Cu(II). Specific behavior, depending upon the introduced metal, was highlighted by different redox reaction processes and also metastable decompositions (in PSD mode).
Budimir
Natali
N
Equipe de Spectrométrie de masse (LCSOB), UMR 7613 CNRS (Synthèse, Structure et Fonction de Molécules Bioactives), B45, Université Pierre et Marie Curie, 4 place Jussieu, 75252 Paris Cedex 05, France.
Blais
Jean-Claude
JC
Fournier
Françoise
F
Tabet
Jean-Claude
JC
D000085:Acetates / Q000737:chemistry; D002412:Cations / Q000737:chemistry*; D002712:Chlorides / Q000737:chemistry; D003300:Copper / Q000737:chemistry; D019281:Dimerization; D005227:Fatty Acids / Q000737:chemistry*; D005296:Ferrous Compounds / Q000737:chemistry; D013058:Mass Spectrometry / Q000379:methods*; D019216:Metals, Heavy / Q000737:chemistry*; D010084:Oxidation-Reduction; D016062:Porosity; D012825:Silicon; D018030:Silver Compounds / Q000737:chemistry; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; D017967:Zinc Compounds / Q000737:chemistry
D000085:Acetates; D002412:Cations; D002712:Chlorides; D005227:Fatty Acids; D005296:Ferrous Compounds; D019216:Metals, Heavy; D018030:Silver Compounds; D017967:Zinc Compounds; C103100:silver acetate; D003300:Copper; C016837:zinc chloride; C517969:nonadecanoic acid; C517970:heneicosanoic acid; C029892:cupric chloride; C029451:ferrous chloride; D012825:Silicon