title: Regular exercise attenuated lipid peroxidation in adolescents with Down's syndrome.
abstract: OBJECTIVE
  This study was designed to ascertain whether regular exercise may attenuate lipid peroxidation in adolescents with Down's syndrome.
  
  
  METHODS
  Thirty-one male adolescents with Down's syndrome performed a 12-week training program, 3 days/week at a work intensity of 60-75% of peak heart rate (HRmax=194.5-[0.56 age]). Plasmatic malondialdehyde (MDA) was determined by high performance liquid chromatography (HPLC).
  
  
  RESULTS
  When compared to baseline, MDA content was decreased significantly.
  
  
  CONCLUSIONS
  Regular exercise significantly decreased lipoperoxidation in Down's syndrome.
authors.affiliation: Sport Medicine School, Virgen del Saliente s/n, 11100 San Fernando, Cádiz, Spain.
authors.forename: Francisco
authors.initials: F
authors.lastname: Javier Ordonez
authors.forename: Manuel
authors.initials: M
authors.lastname: Rosety-Rodriguez
mesh_terms: D000293:Adolescent; D004314:Down Syndrome / Q000097:blood / Q000378:metabolism*; D015444:Exercise / Q000502:physiology*; D006801:Humans; D015227:Lipid Peroxidation; D008297:Male; D008315:Malondialdehyde / Q000097:blood
chemical_list: D008315:Malondialdehyde