title: Eosinophil cationic protein, specific IgE and IgG4 in human toxocariasis.
abstract: Among 67 French patients presenting a toxocaral infection, various demographic, environmental, clinical and laboratory parameters (blood eosinophil count, eosinophil cationic protein (ECP), serum total IgE, specific IgE against common inhalant allergens, specific IgE and IgG4 against Toxocara excretory-secretory antigens) were investigated. Correlation studies and logistic regression analyses were conducted, testing elevated levels of ECP, specific anti-Toxocara IgE or IgG4 as outcome variables An elevated ECP level was significantly associated with both cough and rhinitis, a high level of specific anti-Toxocara IgE with itchy rashes and possible atopic status, and an increase of specific anti-Toxocara IgG4 with rural residence.
authors.affiliation: Department of Parasitology, CH Rangueil, University Hospitals, 31059 Toulouse 9, France. magnaval@cict.fr
authors.forename: J-F
authors.initials: JF
authors.lastname: Magnaval
authors.forename: J-H
authors.initials: JH
authors.lastname: Faufingue
authors.forename: B
authors.initials: B
authors.lastname: Morassin
authors.forename: R
authors.initials: R
authors.lastname: Fabre
mesh_terms: D000328:Adult; D000818:Animals; D000909:Antibodies, Helminth / Q000097:blood*; D000947:Antigens, Helminth / Q000276:immunology; D015153:Blotting, Western; D047150:Eosinophil Cationic Protein / Q000097:blood*; D005260:Female; D005602:France; D006801:Humans; D006967:Hypersensitivity / Q000276:immunology / Q000469:parasitology; D007073:Immunoglobulin E / Q000097:blood*; D007074:Immunoglobulin G / Q000097:blood*; D007814:Larva; D007958:Leukocyte Count; D016015:Logistic Models; D008297:Male; D012424:Rural Population; D012698:Serologic Tests; D018709:Statistics, Nonparametric; D017166:Toxocara canis / Q000276:immunology*; D014120:Toxocariasis / Q000175:diagnosis* / Q000276:immunology
chemical_list: D000909:Antibodies, Helminth; D000947:Antigens, Helminth; D007074:Immunoglobulin G; D007073:Immunoglobulin E; D047150:Eosinophil Cationic Protein