Gold-catalyzed synthesis of substituted tetrahydronaphthalenes.
We report a gold-catalyzed benzannulation of 3-hydroxy-1,5-enynes to generate tetrahydronaphthalenes. This mild process proves to be an effective method to synthesize various metasubstituted aromatic rings in good yields. [reaction: see text]
Grisé
Christiane M
CM
Center for Catalysis Research and Innovation, Department of Chemistry, 10 Marie Curie, University of Ottawa, Ottawa, Ontario, Canada K1N 6N5.
Barriault
Louis
L
D002384:Catalysis; D003500:Cyclization; D006046:Gold / Q000737:chemistry*; D007202:Indicators and Reagents; D007536:Isomerism; D009682:Magnetic Resonance Spectroscopy; D013764:Tetrahydronaphthalenes / Q000138:chemical synthesis*
D007202:Indicators and Reagents; D013764:Tetrahydronaphthalenes; D006046:Gold