Acute chorea associated with metoclopramide use.
Metoclopramide is a dopamine receptor antagonist that is used to treat diabetic gastroparesis, chemotherapy-induced nausea, and migraines. It is known to cause extrapyramidal side effects such as tardive dyskinesia, parkinsonism, dystonia, and akithisia, but not chorea. We describe a patient who presented with choreiform movements shortly after the administration of intravenous metoclopramide. Her work-up for secondary causes of chorea was otherwise negative and her symptoms abated with the administration of oral quetiapine and intravenous diazepam.
Dubow
Jordan S
JS
Department of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
Leikin
Jerrold
J
Rezak
Michael
M
D000208:Acute Disease; D000328:Adult; D002819:Chorea / Q000139:chemically induced*; D018492:Dopamine Antagonists / Q000009:adverse effects*; D004409:Dyskinesia, Drug-Induced / Q000209:etiology*; D005260:Female; D006801:Humans; D008787:Metoclopramide / Q000009:adverse effects*
D018492:Dopamine Antagonists; D008787:Metoclopramide