title: Hormone profiles and treatments in the late pregnant mare.
abstract: Evaluation of hormone profiles in late pregnancy is one of the major determinants of fetoplacental compromise in equine clinical practice. Use of hormone therapies is subjective and reflects, to a large extent, our lack of understanding about the endocrine relations between the mare, placenta, and fetus. This article describes the normal endocrine events in late gestation, the abnormal hormone patterns associated with fetoplacental dysfunction, and the hormone interventions that are currently used or could be used to improve pregnancy outcome.
authors.affiliation: The Equine Fertility Unit, Department of Veterinary Medicine, University of Cambridge, Mertoun Paddocks, Woodditton Road, Newmarket, Suffolk, CB8 9BH United Kingdom. efu@tesco.net
authors.forename: J C
authors.initials: JC
authors.lastname: Ousey
mesh_terms: D000818:Animals; D004967:Estrogens / Q000502:physiology; D005260:Female; D005333:Fetus / Q000502:physiology; D005938:Glucocorticoids / Q000627:therapeutic use; D006728:Hormones / Q000502:physiology* / Q000627:therapeutic use; D006736:Horses / Q000502:physiology*; D006854:Hydrocortisone / Q000502:physiology; D010121:Oxytocin / Q000502:physiology; D036801:Parturition / Q000502:physiology*; D010920:Placenta / Q000502:physiology; D011247:Pregnancy; D011248:Pregnancy Complications / Q000503:physiopathology; D011270:Pregnancy, Animal / Q000097:blood*; D047928:Premature Birth / Q000662:veterinary; D011374:Progesterone / Q000627:therapeutic use; D011372:Progestins / Q000502:physiology; D011448:Prostaglandin Antagonists / Q000627:therapeutic use; D011453:Prostaglandins / Q000819:agonists / Q000502:physiology*; D012065:Relaxin / Q000502:physiology
chemical_list: D004967:Estrogens; D005938:Glucocorticoids; D006728:Hormones; D011372:Progestins; D011448:Prostaglandin Antagonists; D011453:Prostaglandins; D011374:Progesterone; D010121:Oxytocin; D012065:Relaxin; D006854:Hydrocortisone