title: Echinococcosis: a possible etiology in psoriatic disease.
abstract: We aimed to investigate seroprevalence of Echinococcus granulosus in patients with psoriasis to determine a possible etiologic role, since both echinococcosis and psoriasis are defined as T cell-mediated diseases. Forty psoriatic patients and 50 age- and sex-matched control subjects were included in the study. IgG-specific ELISA was used to determine seropositivity. E. granulosus-specific IgG antibodies were found to be positive in 17/40 (42.5%) of the patients with psoriasis and in 11/50 (22%) of the control subjects (p = 0.008). Our results suggest that echinococcosis might be one of the causative pathogens in the etiopathogenesis of psoriasis in highly endemic regions.
authors.affiliation: Department of Microbiology, Kirikkale University Faculty of Medicine, Kirikkale, Turkey. teomanapan@yahoo.com
authors.forename: Teoman Zafer
authors.initials: TZ
authors.lastname: Apan
authors.forename: Sedat
authors.initials: S
authors.lastname: Kaygusuz
mesh_terms: D000328:Adult; D000368:Aged; D000818:Animals; D000909:Antibodies, Helminth / Q000097:blood; D016022:Case-Control Studies; D004443:Echinococcosis / Q000150:complications* / Q000276:immunology; D048209:Echinococcus granulosus / Q000276:immunology / Q000302:isolation & purification*; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D008297:Male; D008875:Middle Aged; D011565:Psoriasis / Q000276:immunology / Q000469:parasitology*; D016036:Seroepidemiologic Studies
chemical_list: D000909:Antibodies, Helminth; D007074:Immunoglobulin G