title: Non-Hodgkin's lymphoma of mucosa-associated lymphoid tissue.
abstract: The concept of mucosa-associated lymphoid tissue (MALT) lymphomas was introduced by Isaacson and Wright [Cancer 1983; 52:1410-1416] in 1983. After more than 20 years of clinical research MALT lymphomas are now recognized as a distinct subtype of non-Hodgkin's lymphoma (NHL) with unique pathogenic, histological, and clinical features. Although this subtype of NHL occurs frequently, optimal management remains elusive. This manuscript reviews features of the clinical presentation, diagnosis, pathology, molecular characteristics, and management of both gastric and non-gastric MALT lymphoma.
authors.affiliation: St. Luke's-Roosevelt Hospital Center, New York, NY 10019, USA.
authors.forename: Seth M
authors.initials: SM
authors.lastname: Cohen
authors.forename: Magdalena
authors.initials: M
authors.lastname: Petryk
authors.forename: Mala
authors.initials: M
authors.lastname: Varma
authors.forename: Peter S
authors.initials: PS
authors.lastname: Kozuch
authors.forename: Elizabeth D
authors.initials: ED
authors.lastname: Ames
authors.forename: Michael L
authors.initials: ML
authors.lastname: Grossbard
mesh_terms: D006801:Humans; D018442:Lymphoma, B-Cell, Marginal Zone / Q000175:diagnosis / Q000235:genetics / Q000628:therapy; D008228:Lymphoma, Non-Hodgkin / Q000175:diagnosis / Q000235:genetics / Q000628:therapy; D009367:Neoplasm Staging; D016896:Treatment Outcome