title: Noradrenalin-secreting retroperitoneal schwannoma resected by hand-assisted laparoscopic surgery: report of a case.
abstract: A 66-year-old woman was admitted to our hospital for investigation of a retroperitoneal mass. She was asymptomatic but her serum noradrenalin and vanillylmandellic acid levels were increased remarkably. Computed tomographic angiography showed a mass in the left side of the superior mesenteric artery (SMA) divergence, 6 x 4 cm in size, supplied mainly by the left adrenal artery. We performed hand-assisted laparoscopic surgery (HALS) using a Cavitron ultrasonic surgical aspirator. Abdominal exploration revealed that the tumor was located in the left side of the SMA root, but was not adhered to the adjacent organs. Her vital signs remained stable during the operation. Microscopic examination revealed a palisade formation, confirming a histopathological diagnosis of degenerated schwannoma (Antoni type B). Immunohistologically, the tumor cells were stained with S-100 protein and neuron-specific enolase. Her noradrenalin level normalized immediately after the operation and she remains in good health 3 years 2 months later.
authors.affiliation: First Department of Surgery, Mie University Graduate School of Medicine, 2-17-4 Edobashi, Tsu, Mie 514-8507, Japan.
authors.forename: Tomohide
authors.initials: T
authors.lastname: Hori
authors.forename: Kentaro
authors.initials: K
authors.lastname: Yamagiwa
authors.forename: Shintaro
authors.initials: S
authors.lastname: Yagi
authors.forename: Taku
authors.initials: T
authors.lastname: Iida
authors.forename: Kentaro
authors.initials: K
authors.lastname: Taniguchi
authors.forename: Chiduru
authors.initials: C
authors.lastname: Yamamoto
authors.forename: Yukitsuna
authors.initials: Y
authors.lastname: Eshita
authors.forename: Yuji
authors.initials: Y
authors.lastname: Kozuka
authors.forename: Haruyuki
authors.initials: H
authors.lastname: Takaki
authors.forename: Takuma
authors.initials: T
authors.lastname: Kato
authors.forename: Kanako
authors.initials: K
authors.lastname: Saito
authors.forename: Mie
authors.initials: M
authors.lastname: Torii
authors.forename: Syuji
authors.initials: S
authors.lastname: Isaji
authors.forename: Shinji
authors.initials: S
authors.lastname: Uemoto
mesh_terms: D000368:Aged; D000792:Angiography; D014408:Biomarkers, Tumor / Q000097:blood; D003937:Diagnosis, Differential; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D010535:Laparoscopy / Q000379:methods*; D008279:Magnetic Resonance Imaging; D009442:Neurilemmoma / Q000097:blood / Q000175:diagnosis / Q000601:surgery*; D009638:Norepinephrine / Q000378:metabolism*; D012186:Retroperitoneal Neoplasms / Q000097:blood / Q000175:diagnosis / Q000601:surgery*; D014057:Tomography, X-Ray Computed
chemical_list: D014408:Biomarkers, Tumor; D009638:Norepinephrine