title: Bier's white spots associated with scleroderma renal crisis.
abstract: Bier's spots are asymptomatic and permanent white macules, standing on a cyanotic background. These spots are associated with venous stasis and usually appear in physiological conditions. We report the case of a 47-year-old woman with a 2-year history of systemic scleroderma, who developed Bier's white spots associated with a vascular and renal crisis. Interestingly, these spots appeared with the crisis, and disappeared with the treatment and resolution of the crisis. They are probably a result of anatomical and functional damage to the small vessels of the skin. The pathophysiology in the skin is probably the same as that which happens in renal vessels during scleroderma renal crisis.
authors.affiliation: Department of Dermatology, Teaching Dupuytren University Hospital, Limoges, France. ipeyrot@yahoo.fr
authors.forename: I
authors.initials: I
authors.lastname: Peyrot
authors.forename: S
authors.initials: S
authors.lastname: Boulinguez
authors.forename: A
authors.initials: A
authors.lastname: Sparsa
authors.forename: Y
authors.initials: Y
authors.lastname: Le Meur
authors.forename: J-M
authors.initials: JM
authors.lastname: Bonnetblanc
authors.forename: C
authors.initials: C
authors.lastname: Bedane
mesh_terms: D000806:Angiotensin-Converting Enzyme Inhibitors / Q000627:therapeutic use; D002216:Captopril / Q000627:therapeutic use; D005260:Female; D006801:Humans; D017496:Hypopigmentation / Q000209:etiology* / Q000628:therapy; D007676:Kidney Failure, Chronic / Q000150:complications* / Q000628:therapy; D008875:Middle Aged; D011241:Prednisone / Q000627:therapeutic use; D006435:Renal Dialysis; D012595:Scleroderma, Systemic / Q000150:complications* / Q000628:therapy; D016896:Treatment Outcome
chemical_list: D000806:Angiotensin-Converting Enzyme Inhibitors; D002216:Captopril; D011241:Prednisone