title: Paralytic ileus associated with combined atypical antipsychotic therapy.
abstract: First- and second-generation antipsychotics commonly cause mild and sometimes severe gastrointestinal motility depression. We discuss a case of a patient who developed paralytic ileus during his treatment with a combination of second-generation antipsychotics. The patient did not receive other medication that could cause depression of intestinal motility than the above-mentioned combination of antipsychotics and no other etiology could be found for the ileus. Furthermore we discuss the theoretical background of antipsychotics induced gastrointestinal motility depression and we provide the literature review of case reports of this topic.
authors.affiliation: National Institute for Psychiatry and Neurology, Budapest, 27 POB 1, 1281, Huvosvolgyi u 116, Hungary. dome_peter@yahoo.co.uk
authors.forename: Peter
authors.initials: P
authors.lastname: Dome
authors.forename: Zsofia
authors.initials: Z
authors.lastname: Teleki
authors.forename: Reka
authors.initials: R
authors.lastname: Kotanyi
mesh_terms: D014150:Antipsychotic Agents / Q000009:adverse effects*; D004359:Drug Therapy, Combination; D006801:Humans; D007418:Intestinal Pseudo-Obstruction / Q000139:chemically induced*; D008297:Male; D008875:Middle Aged; D012559:Schizophrenia / Q000188:drug therapy
chemical_list: D014150:Antipsychotic Agents