title: Typical bronchopulmonary carcinoid tumors: a ramifying bronchial presentation with metastatic behavior.
abstract: Bronchopulmonary typical carcinoid tumors (BTCT) are neuroendocrine neoplasms with histologic low grade characteristics considered benign. However, despite reassuring histologic classification, some of them demonstrate an aggressive nature and metastatic behavior. During a not yet concluded study aiming at establishing criteria to predict this metastatic behavior, three uncommon cases were observed. Metastasis occurred despite typical carcinoid microscopic features in 3 female patients of African origin presenting at macroscopic examination as ramifying bronchopulmonary typical carcinoid tumors following the bronchial tree. We suggest that clinical ramifying presentation may be related to metastatic behavior, even for bronchopulmonary typical carcinoid tumors not displaying histologic criteria for atypical carcinoid tumors.
authors.affiliation: Hôpital Européen Georges Pompidou, Thoracic Surgery Department, Paris V University, Paris, France.
authors.forename: João-Carlos
authors.initials: JC
authors.lastname: Das-Neves-Pereira
authors.forename: Leandro Luongo
authors.initials: LL
authors.lastname: de Matos
authors.forename: Claire
authors.initials: C
authors.lastname: Danel
authors.forename: Damila
authors.initials: D
authors.lastname: Trufelli
authors.forename: Marc
authors.initials: M
authors.lastname: Riquet
mesh_terms: D000368:Aged; D001984:Bronchial Neoplasms / Q000473:pathology* / Q000601:surgery; D002276:Carcinoid Tumor / Q000473:pathology* / Q000601:surgery; D005260:Female; D006801:Humans; D009362:Neoplasm Metastasis; D011013:Pneumonectomy