Investigation of the functional variant c.-169T > C of the Fc receptor-like 3 (FCRL3) gene in alopecia areata.
A functional variant in the Fc receptor-like 3 (FCRL3) gene has been implicated in susceptibility to autoimmune diseases such as rheumatoid arthritis, systemic lupus erythematosus and autoimmune thyroid disease. Investigating a large case-control sample of patients with alopecia areata (AA), we found no evidence for the involvement of FCRL3 in susceptibility to AA.
Schäfer
N
N
Institute of Human Genetics, University of Bonn, Bonn, Germany.
Blaumeiser
B
B
Becker
T
T
Freudenberg-Hua
Y
Y
Hanneken
S
S
Eigelshoven
S
S
Schmael
C
C
Lambert
J
J
De Weert
J
J
Kruse
R
R
Nöthen
M M
MM
Betz
R C
RC
D000293:Adolescent; D000328:Adult; D000368:Aged; D000506:Alopecia Areata / Q000235:genetics*; D016022:Case-Control Studies; D002648:Child; D003596:Cytosine; D005260:Female; D020022:Genetic Predisposition to Disease; D014644:Genetic Variation; D006801:Humans; D008297:Male; D008875:Middle Aged; D020641:Polymorphism, Single Nucleotide; D011971:Receptors, Immunologic / Q000235:genetics*; D013941:Thymine
C457775:FCRL3 protein, human; D011971:Receptors, Immunologic; D003596:Cytosine; D013941:Thymine