Sudden change of a large congenital melanocytic nevus to neurocutaneous melanosis.
Neurocutaneous melanosis (NCM) is a congenital phakomatosis in which large congenital melanocytic nevi are associated with a benign or malignant melanocytic tumor of the leptomeninges. Because the prognosis of patients with symptomatic NCM is poor, it is essential to monitor the large congenital melanocytic patient regularly for a neurological evaluation. However, it has not been reported how quickly the lesion could appear. We observed a case of NCM suddenly developing in a large congenital melanocytic nevi patient. With this case, the NCM had developed within six months and was aggravated during the subsequent six months.
Lee
Choong Jae
CJ
Department of Plastic and Reconstructive Surgery, College of Medicine, Inha University, Incheon, South Korea. cjlee313@hotmail.com
Park
Jun Ho
JH
Lee
Se Il
SI
D001932:Brain Neoplasms / Q000209:etiology* / Q000601:surgery; D002648:Child; D017809:Fatal Outcome; D006801:Humans; D008297:Male; D008545:Melanoma / Q000209:etiology* / Q000601:surgery; D008548:Melanosis / Q000209:etiology*; D020752:Neurocutaneous Syndromes / Q000209:etiology*; D009508:Nevus, Pigmented / Q000150:complications*; D012878:Skin Neoplasms / Q000150:complications*