Optical biosensors: where next and how soon?
From a direct comparison of the technical benefits of labelled reporter assays with the benefits of label-free assays, label-free appears to have significant advantages. Faster assay development times; accurate, high information content data; and less interference from labels. However, optical label-free platforms have not yet made a major impact in the drug discovery technology markets; are often viewed as having poor throughput, limited application; and are difficult to learn and use effectively.
Cooper
Matthew A
MA
Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK. mc221@cam.ac.uk
D015374:Biosensing Techniques / Q000295:instrumentation* / Q000379:methods; D015195:Drug Design; D040541:Marketing / Q000379:methods / Q000639:trends; D055095:Optics and Photonics / Q000295:instrumentation*; D013678:Technology, Pharmaceutical / Q000295:instrumentation / Q000379:methods / Q000639:trends; D013997:Time Factors