title: Antiquitin, a relatively unexplored member in the superfamily of aldehyde dehydrogenases with diversified physiological functions.
abstract: Antiquitin is a member of the aldehyde dehydrogenase superfamily. Sequence analyses indicate that the protein is highly conserved from plants to animals. The plant antiquitins are generally believed to play a role in osmoregulation and/or detoxification. The physiological functions of animal antiquitins remain largely elusive, their involvement in a number of human diseases has been implicated.
authors.affiliation: Department of Biochemistry, The Chinese University of Hong Kong, Shatin, N. T., Hong Kong, China. wpfong@cuhk.edu.hk
authors.forename: W-P
authors.initials: WP
authors.lastname: Fong
authors.forename: C H K
authors.initials: CH
authors.lastname: Cheng
authors.forename: W-K
authors.initials: WK
authors.lastname: Tang
mesh_terms: D000444:Aldehyde Dehydrogenase / Q000502:physiology*; D000818:Animals; D006801:Humans; D050647:L-Aminoadipate-Semialdehyde Dehydrogenase; D008969:Molecular Sequence Data; D010940:Plant Proteins / Q000502:physiology*; D011506:Proteins / Q000502:physiology; D014882:Water-Electrolyte Balance
chemical_list: D010940:Plant Proteins; D011506:Proteins; C089507:ALDH7A1 protein, human; D000444:Aldehyde Dehydrogenase; C484224:Aldh7a1 protein, rat; D050647:L-Aminoadipate-Semialdehyde Dehydrogenase