Cytomegalovirus pneumonia after stem cell transplantation: correlation of CT findings with clinical outcome in 30 patients.
OBJECTIVE
The purpose of our study was to assess the correlation between early high-resolution CT findings of cytomegalovirus (CMV) pneumonia in patients with blood disorders and their clinical outcomes.


CONCLUSIONS
The initial high-resolution CT findings in immunocompromised patients with CMV pneumonia seem to predict the patient's outcome being unfavorable in those forms of disease beginning mostly bilaterally as diffuse or patchy ground-glass opacity followed by progressive air-space consolidation. Also, a change in the CT morphology of pulmonary lesions toward diffuse ground-glass opacity seems to correlate with an unfavorable disease course.
Horger
Marius S
MS
Department of Diagnostic Radiology, Eberhard-Karls-University, Hoppe-Seyler-Strasse 3, Tuebingen 72076, Germany. mshorger@med.uni-tuebingen.de
Pfannenberg
Christina
C
Einsele
Hermann
H
Beck
Robert
R
Hebart
Holger
H
Lengerke
Claudia
C
Vonthein
Reinhard
R
Wehrmann
Manfred
M
Faul
Christoph
C
Claussen
Claus
C
D000328:Adult; D003586:Cytomegalovirus Infections / Q000000981:diagnostic imaging* / Q000209:etiology*; D005260:Female; D019337:Hematologic Neoplasms / Q000628:therapy; D006801:Humans; D016867:Immunocompromised Host; D008297:Male; D008875:Middle Aged; D011014:Pneumonia / Q000000981:diagnostic imaging* / Q000209:etiology / Q000821:virology*; D011379:Prognosis; D011859:Radiography; D012189:Retrospective Studies; D012307:Risk Factors; D033581:Stem Cell Transplantation / Q000009:adverse effects*; D016896:Treatment Outcome