title: Numerical modeling of the transport to an intravascular bubble in a tube with a soluble/insoluble surfactant.
abstract: Using a newly developed algorithm in conjunction with the front tracking scheme, we have evaluated the transport associated with a deformable bubble moving in a tube in the presence of a soluble or an insoluble surfactant. Such evaluations are useful to the understanding of gas embolism--a common syndrome for decompression sickness. Decompression sickness may be encountered in performing extravehicular activity during space exploration. The numerical evaluations indicate that as the location of the adsorptive interface gets closer to the vessel wall, the surfactant amount on the wall gets depleted. The implication is that the process by which a bubble occluding a vessel dislodges may depend both on the strength of the diffusivity of the surfactant and the adsorption process. More detailed study is needed to clarify this observation. The numerical results evaluated include Marangoni flow, which causes a bubble to propel out of its initial static location, and bubble motion in Poiseuille flow. The presence of a soluble/insoluble surfactant slows down the bubble motion. For identical surface concentrations of the surfactant, the effect of the presence of a soluble surfactant is more severe on the retardation of the bubble motion than that of an insoluble surfactant.
authors.affiliation: Department of Mechanical Engineering and Applied Mechanics, University of Pennsylvania, Philadelphia, PA 19104-6315, USA. ayya@seas.upenn.edu
authors.forename: Portonovo S
authors.initials: PS
authors.lastname: Ayyaswamy
authors.forename: Jie
authors.initials: J
authors.lastname: Zhang
authors.forename: David M
authors.initials: DM
authors.lastname: Eckmann
mesh_terms: D000465:Algorithms; D003198:Computer Simulation; D004618:Embolism, Air / Q000503:physiopathology*; D006801:Humans; D008955:Models, Cardiovascular; D009038:Motion; D011655:Pulmonary Embolism / Q000503:physiopathology; D012212:Rheology; D012995:Solubility; D013500:Surface Tension; D013501:Surface-Active Agents / Q000737:chemistry / Q000494:pharmacology*
chemical_list: D013501:Surface-Active Agents