title: [Evaluation of aroeira (Schinus terebinthifolius Raddi) extract on the healing process of gastroraphy in rats].
abstract: OBJECTIVE
  To evaluate the healing process of gastric suture in rats using hydroalcoholic aroeira (Schinus terebinthifolius Raddi) extract.
  
  
  METHODS
  Forty adult male rats, divided into two groups of 20 animals were operated and named as follows: aroeira group (Ga), and the control group (Gc). Each group was divided into two subgroups (SG) of 10 animals (SGa and SGc) according to the time of provoked death (three and seven days). The same surgical procedure was performed in all animals consisting in incision and simple suture of the stomach (Prolene(R) 6-0). The only difference was on the type of medical treatment. The aroeira group received a single 100 mg/kg of aroeira extract in an intraperitoneal dose and the animals from the control group received the same quantity in milliliters (ml) of the isotonic saline solution. The evaluated parameters were: macroscopic alterations, microscopic healing process and toleration to atmospheric air insufflation.
  
  
  RESULTS
  All animals had good healing process of abdominal wall with no clinical evidence of infection, dehiscence, abscesses and peritonitis. Both groups presented adherences to gastric suture line area with surrounding organs, mainly the liver, lower intestines and the abdominal wall. Microscopic analysis showed only chronic inflammation significant difference between the aroeira and control groups on the third day of observation. Resistance tests did not present significant statistical differences in the studied groups.
  
  
  CONCLUSIONS
  The use of aroeira (Schinus terebinthifolius Raddi) hydro-alcoholic extract did not alter the stomach healing process, considered on macroscopic, tensiometric and microscopic assessment.
authors.affiliation: Departamento de Cirurgia, Universidade Federal do Maranhao.
authors.forename: Orlando José dos
authors.initials: OJ
authors.lastname: Santos
authors.forename: Jurandir Marcondes
authors.initials: JM
authors.lastname: Ribas Filho
authors.forename: Nicolau Gregori
authors.initials: NG
authors.lastname: Czeczko
authors.forename: Manoel Lages
authors.initials: ML
authors.lastname: Castelo Branco Neto
authors.forename: Carlos
authors.initials: C
authors.lastname: Naufel
authors.forename: Lydia Masako
authors.initials: LM
authors.lastname: Ferreira
authors.forename: Rodrigo Peixoto
authors.initials: RP
authors.lastname: Campos
authors.forename: Hamilton
authors.initials: H
authors.lastname: Moreira
authors.forename: Rafael Dib
authors.initials: RD
authors.lastname: Porcides
authors.forename: Samuel
authors.initials: S
authors.lastname: Dobrowolski
mesh_terms: D027926:Anacardiaceae / Q000737:chemistry*; D000704:Analysis of Variance; D000818:Animals; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D004195:Disease Models, Animal; D004353:Drug Evaluation, Preclinical; D007249:Inflammation / Q000188:drug therapy; D007274:Injections, Intraperitoneal; D008297:Male; D008517:Phytotherapy; D024301:Plant Bark / Q000737:chemistry; D010936:Plant Extracts / Q000627:therapeutic use; D051381:Rats; D017208:Rats, Wistar; D013270:Stomach / Q000601:surgery*; D013718:Tensile Strength / Q000187:drug effects; D013997:Time Factors; D014945:Wound Healing / Q000187:drug effects* / Q000502:physiology
chemical_list: D000893:Anti-Inflammatory Agents; D010936:Plant Extracts