Strongyloidiasis with gastric mucosal invasion presenting with acute interstitial nephritis.
We report an atypical occurrence of invasive Strongyloides stercoralis infection of the stomach mucosa in an elderly female patient from Bangka Island, northwestern Indonesia. The patient presented with severe epigastric pain, edema of the legs, proteinuria and severe hypoalbuminemia. Gastric and duodenal biopsies found eggs, larval and adult forms present in the superficial mucosa with mild inflammation. The Harada-Mori filter paper culture technique revealed S. stercoralis filariform larvae and free-living adult worms, corroborating the diagnosis. The infection was associated with acute interstitial nephritis. The patient showed rapid and dramatic improvement after treatment with mebendazole.
Bangs
Michael J
MJ
US Naval Medical Research Unit No. 2, Jakarta, Indonesia. bangs_michael@yahoo.com
Sirait
Sontan
S
Purnomo
Maguire
Jason D
JD
D000368:Aged; D000818:Animals; D005260:Female; D005753:Gastric Mucosa / Q000469:parasitology*; D006801:Humans; D007214:Indonesia; D008463:Mebendazole / Q000627:therapeutic use; D009395:Nephritis, Interstitial / Q000209:etiology*; D013321:Strongyloides / Q000302:isolation & purification*; D013322:Strongyloidiasis / Q000150:complications* / Q000188:drug therapy / Q000473:pathology*
D008463:Mebendazole