title: Primary dural lymphomas: a review.
abstract: Primary dural lymphoma (PDL) is a rare subtype of primary central nervous system lymphoma (PCNSL) that arises from the dura mater and differs biologically from other CNS lymphomas. The PDL is usually a low-grade marginal zone lymphoma (MZL), whereas other types of PCNSLs are usually high-grade, diffuse, large B-cell lymphomas. A PDL usually presents with single or multiple extraaxial masses that enhance diffusely with addition of contrast material and can be confused with meningioma. The MZLs respond well to local therapy such as surgery and radiation treatment. Most patients attain complete response and have good local disease control. Nevertheless, the risk of systemic relapse appears to be high, probably because the dura mater is outside of the blood-brain barrier.
authors.affiliation: Department of Neurology, Memorial Sloan-Kettering Cancer Center, New York, New York, 10021, USA.
authors.forename: Fabio M
authors.initials: FM
authors.lastname: Iwamoto
authors.forename: Lauren E
authors.initials: LE
authors.lastname: Abrey
mesh_terms: D004388:Dura Mater / Q000473:pathology*; D006801:Humans; D016393:Lymphoma, B-Cell / Q000473:pathology* / Q000532:radiotherapy / Q000601:surgery*; D016403:Lymphoma, Large B-Cell, Diffuse / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery; D008577:Meningeal Neoplasms / Q000473:pathology* / Q000532:radiotherapy / Q000601:surgery*