Antibacterial activity and composition of the essential oil of Ziziphora clinopodioides subsp. bungeana (Juz.) Rech. f. from Iran.
The chemical composition of the essential oil obtained from the aerial flowering parts of Ziziphora clinopodioides subsp. bungeana (Juz.) Rech. f. was analyzed by GC and GC-MS. Thirty-two components representing 97.1% of the total oil were identified. Oxygenated monoterpenes (94.3%) were the predominant fraction of the oil with pulegone (65.2%), isomenthone (11.9%), 1,8-cineole (7.8%) and piperitenone (6.5%) as the main constituents. Antibacterial activity of the oil and also its two main components (pulegone and 1,8-cineole) were tested against seven bacteria. It was found that the oil exhibited interesting antibacterial activity against Staphylococcus epidermidis, S. aureus, Escherichia coli and Bacillus subtilis with MIC values of 3.75 mg/ml.
Sonboli
Ali
A
Department of Biology, Medicinal Plants and Drugs Research Institute, Shahid Beheshti University, Evin, P.O. Box 19835-389, Tehran, Iran. a-sonboli@sbu.ac.ir
Mirjalili
Mohammad Hossein
MH
Hadian
Javad
J
Ebrahimi
Samad Nejad
SN
Yousefzadi
Morteza
M
D000900:Anti-Bacterial Agents / Q000302:isolation & purification* / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects; D002849:Chromatography, Gas; D007492:Iran; D019686:Lamiaceae / Q000737:chemistry* / Q000145:classification; D008826:Microbial Sensitivity Tests; D009822:Oils, Volatile / Q000302:isolation & purification* / Q000494:pharmacology*
D000900:Anti-Bacterial Agents; D009822:Oils, Volatile