title: Paraneoplastic neurological syndromes and breast cancer. Regression of paraneoplastic neurological sensorimotor neuropathy in a patient with metastatic breast cancer treated with capecitabine: a case study and mini-review of the literature.
abstract: Paraneoplastic neurological syndromes are a rare complication of breast cancer. Nevertheless, they may be clinically relevant leading to neurological impairment. Clinicians should be aware that these neurological disorders could even precede the diagnosis of breast cancer. Here we present the case of a female patient with advanced breast cancer who developed paraneoplastic sensorimotor neuropathy. Treatment with capecitabine lead to clinical amelioration. A review of the literature on the paraneoplastic neurological syndromes in breast cancer is also included.
authors.affiliation: Department of Medical Oncology, University and S.M. Misericordia Hospital, P.le S.M. della Misericordia, 33100 Udine, Italy. alessandro.minisini@med.uniud.it
authors.forename: Alessandro M
authors.initials: AM
authors.lastname: Minisini
authors.forename: Giada
authors.initials: G
authors.lastname: Pauletto
authors.forename: Paolo
authors.initials: P
authors.lastname: Bergonzi
authors.forename: Gianpiero
authors.initials: G
authors.lastname: Fasola
mesh_terms: D000230:Adenocarcinoma / Q000188:drug therapy* / Q000473:pathology; D000368:Aged; D000964:Antimetabolites, Antineoplastic / Q000627:therapeutic use*; D001943:Breast Neoplasms / Q000188:drug therapy* / Q000473:pathology; D000069287:Capecitabine; D003841:Deoxycytidine / Q000031:analogs & derivatives* / Q000627:therapeutic use; D005260:Female; D005472:Fluorouracil / Q000031:analogs & derivatives* / Q000627:therapeutic use; D006801:Humans; D020364:Paraneoplastic Polyneuropathy / Q000188:drug therapy*; D011355:Prodrugs
chemical_list: D000964:Antimetabolites, Antineoplastic; D011355:Prodrugs; D003841:Deoxycytidine; D000069287:Capecitabine; D005472:Fluorouracil