title: Neuropsychological profile of persons with anoxic brain injury: differences regarding physiopathological mechanism.
abstract: OBJECTIVE
  To determine the neuropsychological profile of persons with anoxic brain injury.
  
  
  METHODS
  A retrospective study on a population of persons with anoxic brain injury admitted to a Brain Injury Unit (Institut Guttmann, Spain) from 1995-2003. The sample was divided according to physiopathological mechanisms in two sub-groups: ischemic anoxia (21 cases) and hypoxemic anoxia (11 cases). Functions assessed included orientation, attention, language, visuo-perceptive and visuo-constructive processing and verbal memory.
  
  
  RESULTS
  Neuropsychological assessment showed diffuse cognitive impairment in all assessed functions. Episodes of ischemic anoxia caused more severe verbal memory and learning problems than episodes of hypoxemic anoxia.
  
  
  CONCLUSIONS
  This study shows that memory problems are the most prominent and relevant impairment, although all other cognitive functions are also impaired, affecting both memory itself and general behaviour. Statistical analysis also provides preliminary evidence on the different profile of memory impairment whether cerebral anoxia had hypoxic or ischemic origin.
authors.affiliation: Institut Universitari de Neurorehabilitació Guttmann-UAB, Badalona, Spain.
authors.forename: A
authors.initials: A
authors.lastname: Garcia-Molina
authors.forename: T
authors.initials: T
authors.lastname: Roig-Rovira
authors.forename: A
authors.initials: A
authors.lastname: Enseñat-Cantallops
authors.forename: R
authors.initials: R
authors.lastname: Sanchez-Carrion
authors.forename: N
authors.initials: N
authors.lastname: Pico-Azanza
authors.forename: M
authors.initials: M
authors.lastname: Bernabeu
authors.forename: J M
authors.initials: JM
authors.lastname: Tormos
mesh_terms: D000328:Adult; D000342:Affective Symptoms; D000368:Aged; D001930:Brain Injuries / Q000503:physiopathology / Q000523:psychology*; D005260:Female; D006801:Humans; D002534:Hypoxia, Brain / Q000503:physiopathology / Q000523:psychology*; D007806:Language Disorders / Q000209:etiology; D008297:Male; D008569:Memory Disorders / Q000209:etiology; D008875:Middle Aged; D019964:Mood Disorders / Q000209:etiology; D009483:Neuropsychological Tests; D009949:Orientation; D010468:Perceptual Disorders / Q000209:etiology; D012189:Retrospective Studies; D012920:Social Behavior Disorders / Q000209:etiology; D014706:Verbal Learning