Clindamycin-induced anaphylactic shock during general anesthesia.
Clindamycin-related anaphylactic reaction is rarely reported. We report a male patient with buccal cancer who was undergoing radical neck dissection when life-threatening anaphylactic shock developed soon after intravenous infusion of clindamycin. Immediate cardiopulmonary resuscitation was performed, and the patient recovered uneventfully. Perioperative anaphylactic shock is a serious problem due to the difficulty of judgment and potentially disastrous outcome. Immediate diagnosis and halting of drug infusion should be the first actions taken.
Chiou
Chiuan-Shiou
CS
Department of Anesthesiology, Taipei Veterans General Hospital, Taipei, Taiwan.
Lin
Su-Man
SM
Lin
Shih-Pin
SP
Chang
Wen-Guei
WG
Chan
Kwok-Hon
KH
Ting
Chien-Kun
CK
D000707:Anaphylaxis / Q000139:chemically induced*; D000768:Anesthesia, General; D000900:Anti-Bacterial Agents / Q000009:adverse effects*; D002981:Clindamycin / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008875:Middle Aged
D000900:Anti-Bacterial Agents; D002981:Clindamycin