Molecularly imprinted polymer microspheres for solid-phase extraction of chloramphenicol residues in foods.
Preparation of molecularly imprinted polymer microspheres (MIPMs) for chloramphenicol (CAP) by aqueous suspension polymerization is reported for the first time in this study. The resulting MIPMs had the ability to specifically adsorb CAP, and the molecularly imprinted solid phase extraction (MISPE) based on the MIPMs was shown to be applicable for clean-up and preconcentration of trace CAP in milk and shrimp samples with high recoveries of 92.7% and 84.9%, respectively. Combined with MISPE, the conventional HPLC-UV analysis sensitivity for CAP in foods could be significantly increased.
Shi
Xizhi
X
Shanghai Jiao Tong University - Shanghai Institutes for Biological Sciences - Pennsylvania State University Joint Center for Life Sciences, Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai 200240, PR China.
Wu
Aibo
A
Zheng
Sulian
S
Li
Rongxiu
R
Zhang
Dabing
D
D000327:Adsorption; D000900:Anti-Bacterial Agents / Q000032:analysis*; D002701:Chloramphenicol / Q000032:analysis*; D002851:Chromatography, High Pressure Liquid / Q000379:methods; D004350:Drug Residues / Q000032:analysis*; D005504:Food Analysis; D008855:Microscopy, Electron, Scanning; D008863:Microspheres; D011108:Polymers / Q000737:chemistry*; D013056:Spectrophotometry, Ultraviolet
D000900:Anti-Bacterial Agents; D011108:Polymers; D002701:Chloramphenicol