Two novel C29-5beta-sterols from the stems of Opuntia dillenii.
Two novel C29-5beta-sterols, opuntisterol [(24R)-24-ethyl-5beta-cholest-9-ene-6beta,12alpha-diol] (1) and opuntisteroside [(24R)-24-ethyl-6beta-[(beta-d-glucopyranosyl)oxy]-5beta-cholest-9-ene-12alpha-ol] (2), together with nine known compounds, beta-sitosterol (3), taraxerol (4), friedelin (5), methyl linoleate (6), 7-oxositosterol (7), 6beta-hydroxystigmast-4-ene-3-one (8), daucosterol (9), methyl eucomate (10) and eucomic acid (11), were isolated from the stems of Opuntia dillenii collected in Guizhou Province, China. Their structures were elucidated mainly by spectroscopic analysis. The absolute configuration of 1 were deduced from comparative 1H NMR data of the (S)- and (R)-methoxyphenyl acetate derivatives. Compounds 6-8, 10 and 11 were isolated from O. dillenii for the first time.
Jiang
Jianqin
J
Department of Phytochemistry, China Pharmaceutical University, Nanjing 210038, PR China. njjjq@yahoo.com.cn
Li
Yanfang
Y
Chen
Zhen
Z
Min
Zhida
Z
Lou
Fengchang
F
D006868:Hydrolysis; D009682:Magnetic Resonance Spectroscopy; D029747:Opuntia / Q000737:chemistry*; D018547:Plant Stems / Q000737:chemistry*; D016339:Spectrometry, Mass, Fast Atom Bombardment; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet; D013261:Sterols / Q000302:isolation & purification*
D013261:Sterols