Eye movement and visual search: are there elementary abnormalities in autism?
Although atypical eye gaze is commonly observed in autism, little is known about underlying oculomotor abnormalities. Our review of visual search and oculomotor systems in the healthy brain suggests that relevant networks may be partially impaired in autism, given regional abnormalities known from neuroimaging. However, direct oculomotor evidence for autism remains limited. This gap is critical since oculomotor abnormalities might play a causal role in functions known to be impaired in autism, such as imitation and joint attention. We integrate our oculomotor review into a developmental approach to language impairment related to nonverbal prerequisites. Oculomotor abnormalities may play a role as a sensorimotor defect at the root of impairments in later developing functional systems, ultimately resulting in sociocommunicative deficits.
Brenner
Laurie A
LA
Brain Development Imaging Laboratory, Department of Psychology, San Diego State University, 6363 Alvarado Ct. #225E, MC1863, San Diego, CA, 92120, USA.
Turner
Katherine C
KC
Müller
Ralph-Axel
RA
D001288:Attention; D001321:Autistic Disorder / Q000453:epidemiology* / Q000503:physiopathology*; D002531:Cerebellum / Q000503:physiopathology; D005149:Facial Expression; D005625:Frontal Lobe / Q000503:physiopathology; D006801:Humans; D015840:Oculomotor Nerve Diseases / Q000453:epidemiology* / Q000503:physiopathology*; D010296:Parietal Lobe / Q000503:physiopathology; D010468:Perceptual Disorders / Q000453:epidemiology* / Q000503:physiopathology*; D017397:Prefrontal Cortex / Q000503:physiopathology; D012438:Saccades / Q000502:physiology*; D013477:Superior Colliculi / Q000503:physiopathology; D013702:Temporal Lobe / Q000503:physiopathology; D014796:Visual Perception