title: Knocking out the Argonautes.
abstract: Argonaute proteins are key players in gene silencing involving small RNAs. In this issue, Yigit et al. (2006) report a comprehensive study of Argonautes in the worm that places many of the 27 family members into a complex gene-silencing network.
authors.affiliation: Hubrecht Laboratory-KNAW, Utrecht, 3584 CT, The Netherlands.
authors.forename: Florian A
authors.initials: FA
authors.lastname: Steiner
authors.forename: Ronald H A
authors.initials: RH
authors.lastname: Plasterk
mesh_terms: D000818:Animals; D017173:Caenorhabditis elegans / Q000378:metabolism*; D015801:Helminth Proteins / Q000378:metabolism*; D034622:RNA Interference; D020871:RNA Stability
chemical_list: D015801:Helminth Proteins