title: Prolonged persistence of fecally excreted ivermectin from reindeer in a sub-arctic environment.
abstract: In December 2001 and 2002, feces from reindeer calves treated with ivermectin were distributed on plots established on two types of forested reindeer pasture in northern Finland. The ungrazed plots were on an enclosure that had been fenced to prevent reindeer access for the last 6 years. The grazed plots were on an area that had been heavily stocked by reindeer during the last 5 years. After enclosures had been established, reindeer and large wildlife were prevented from entering by a fence. Topsoil samples (feces, vegetation, and soil) were collected monthly during the summers of the following 2 years, over a period of from 25 to 95 weeks after deposition. The samples were analyzed for ivermectin using HPLC. Although ivermectin degradation rapidly took place during the first spring, considerable residual ivermectin could be measured throughout the sampling time, showing that ivermectin in feces on pasture may not be photodegraded as rapidly as previously believed. The results support the need for further environmental evaluation studies on the use of ivermectin to control reindeer parasites.
authors.affiliation: Section of Arctic Veterinary Medicine (SAV), Department of Food Safety and Infection Biology, Norwegian School of Veterinary Science, P.O. Box 6204, NO-9292 Tromsø, Norway. kjetil.aasbakk@veths.no
authors.forename: Kjetil
authors.initials: K
authors.lastname: Asbakk
authors.forename: Jackie T
authors.initials: JT
authors.lastname: Hrabok
authors.forename: Antti
authors.initials: A
authors.lastname: Oksanen
authors.forename: Mauri
authors.initials: M
authors.lastname: Nieminen
authors.forename: Peter J
authors.initials: PJ
authors.lastname: Waller
mesh_terms: D000818:Animals; D000977:Antiparasitic Agents / Q000737:chemistry*; D002851:Chromatography, High Pressure Liquid; D004350:Drug Residues / Q000737:chemistry; D004777:Environment; D005243:Feces / Q000737:chemistry*; D005387:Finland; D007559:Ivermectin / Q000737:chemistry*; D012053:Reindeer; D012987:Soil / Q000032:analysis*
chemical_list: D000977:Antiparasitic Agents; D012987:Soil; D007559:Ivermectin