An efficient base-free N-arylation of imidazoles and amines with arylboronic acids using copper-exchanged fluorapatite.
N-Arylation of imidazoles and amines with arylboronic acids was accomplished with copper-exchanged fluorapatite (CuFAP) in methanol at room temperature. The products N-arylimidazoles and N-arylamines were isolated in good to excellent yields. A variety of arylboronic acids were converted to the corresponding N-arylimidazoles and N-arylamines, demonstrating the versatility of the reaction.
Kantam
M Lakshmi
ML
Inorganic and Physical Chemistry Division, Indian Institute of Chemical Technology, Hyderabad 500 007, India. mlakshmi@iict.res.in
Venkanna
Gopaldasu T
GT
Sridhar
Chidara
C
Sreedhar
Bojja
B
Choudary
Boyapati M
BM