[Expression and role of nitric oxide synthase in the testis and epididymis of Macaca fascicularis].
OBJECTIVE
To investigate the expression and the role of nitric oxide synthase (NOS) in the testis and epididymis of macaca fascicularis.


METHODS
The immunohistochemical ABC method was used to observe the localization of nitric oxide synthase in the testis and epididymis of the macaca fascicularis.


RESULTS
(1) nNOS immunoreactivity was found in the spermatogenic cells of seminiferous tubules, the epithelia of epididymal efferent ducts, sperm and the endothelia of blood vessels; (2) iNOS was expressed in the epididymal efferent duct, the sperm inside the duct, and the myoid cells and endothelia of blood vessels; (3) eNOS immunoreactivity was detected in the interstitial cells of the testis, the epididymal efferent duct, the sperm inside the duct, and the myoid cells and endothelia of blood vessels.


CONCLUSIONS
NOS is extensively expressed in the testis and epididymis of the macaca fascicularis and it may play an important role in such processes as spermatogenesis, sperm maturation and testosterone secretion.
Sun
Li
L
Department of Histology and Embryology, Guilin Medical College, Guilin, Guangxi 541004, China. sunli2196@glmc.edu.cn
Ren
Ya-Ping
YP
Jiang
Wei
W
Zhang
Mei-Yan
MY
Hou
Qiao-Yan
QY
D000818:Animals; D004822:Epididymis / Q000378:metabolism*; D007150:Immunohistochemistry; D008252:Macaca fascicularis; D008297:Male; D019001:Nitric Oxide Synthase / Q000096:biosynthesis* / Q000502:physiology; D013737:Testis / Q000378:metabolism*
D019001:Nitric Oxide Synthase