title: Decreased desychronisation during self-paced movements in frequency bands involving sensorimotor integration and motor functioning in Parkinson's disease.
abstract: This study examined sensorimotor integration and motor functioning in seven patients with Parkinson's disease (PD) who had mild symptoms, and seven age-matched controls. Neuro-oscillations were recorded by high-density 128-channel electroencephalography (EEG). Participants were required to perform two tasks: simple tapping of the index finger and thumb and a complex Luria finger apposition task. Both tasks were performed unimanually and bimanually. There were no significant group differences in the task-related power (TRPow) within alpha 1 (mu1) or in beta 1 frequencies (beta1). In contrast, there were significant group differences in the alpha 2 (mu2) and beta 2 frequencies (beta2). Patients had less desychronisation than controls at the electrodes covering the central regions of the scalp. Alpha 2 and beta 2 frequencies have been associated with task-specific sensorimotor integration and motor function, respectively. This activity difference in patients with Parkinson's disease may be due to deficits in sensorimotor integration.
authors.affiliation: Department of Psychology, Research Centre for Cognitive Neuroscience, The University of Auckland, Private Bag 92019, Auckland, New Zealand. v.lim@auckland.ac.nz
authors.forename: Vanessa K
authors.initials: VK
authors.lastname: Lim
authors.forename: Jeff P
authors.initials: JP
authors.lastname: Hamm
authors.forename: Winston D
authors.initials: WD
authors.lastname: Byblow
authors.forename: Ian J
authors.initials: IJ
authors.lastname: Kirk
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001683:Biological Clocks / Q000502:physiology; D001921:Brain / Q000503:physiopathology*; D001931:Brain Mapping; D004569:Electroencephalography; D005071:Evoked Potentials / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009068:Movement / Q000502:physiology*; D009483:Neuropsychological Tests; D010300:Parkinson Disease / Q000503:physiopathology*; D011597:Psychomotor Performance / Q000502:physiology; D012677:Sensation / Q000502:physiology