Normal minipuberty of infancy in boys with Prader-Willi syndrome.
In 4 boys with Prader-Willi syndrome, 3 of whom had cryptorchidism, penile length and plasma testosterone levels at 5 to 10 weeks of life were normal. We suggest that cryptorchidism reflects decreased abdominal pressure rather than hypogonadism, which develops later from progressive degeneration of gonadotropin-releasing hormone neurons.
Fillion
Marc
M
Department of Pediatrics, Endocrinology Service and Research Center, Sainte-Justine Hospital, University of Montreal, Montreal, Canada.
Deal
Cheri L
CL
Van Vliet
Guy
G
D003456:Cryptorchidism; D006801:Humans; D007223:Infant; D008297:Male; D011218:Prader-Willi Syndrome; D011627:Puberty