title: [Determination of 15 trace elements in antineoplastic traditional Chinese medicine by atomic absorption spectrometry].
abstract: Five kinds of antineoplastic traditional Chinese medicines including fufangtianxian capsule, xiaoaiping tablet, zhiling capsule, shenlian capsule and shenlinglan capsule were digested with HNO3-HCl mixed acid. The fifteen trace elements including calcium, magnesium, potassium, sodium, iron, zinc, manganese, cobalt, nickel, chromium, silver, copper, strontium, cadmium and lead in the above-mentioned drugs were determined by atomic adsorption spectrometry. The effects of the kinds of mixed acid, the ratio of HNO3 to HCl in the mixed acid, the volume of digesting solution and the digesting time were also investigated in detail. The results obtained show that the concentrations of Ca, Mg, K, Na, Fe, Zn, Mn, Co and Ni in the five kinds of antineoplastic Chinese traditional medicines are higher than those of other elements.
authors.affiliation: College of Chemistry and Chemical Engineering, Xinyang Normal University, Xinyang 464000, China.
authors.forename: Yan-Ming
authors.initials: YM
authors.lastname: Liu
authors.forename: Hui
authors.initials: H
authors.lastname: Wang
authors.forename: Jin-Tu
authors.initials: JT
authors.lastname: Han
authors.forename: Zhi-Ge
authors.initials: ZG
authors.lastname: Lou
authors.forename: Shi-Ping
authors.initials: SP
authors.lastname: Yue
mesh_terms: D000970:Antineoplastic Agents / Q000032:analysis* / Q000737:chemistry; D002118:Calcium / Q000032:analysis; D003035:Cobalt / Q000032:analysis; D003300:Copper / Q000032:analysis; D006851:Hydrochloric Acid / Q000737:chemistry; D008274:Magnesium / Q000032:analysis; D008345:Manganese / Q000032:analysis; D008516:Medicine, Chinese Traditional; D009532:Nickel / Q000032:analysis; D017942:Nitric Acid / Q000737:chemistry; D011188:Potassium / Q000032:analysis; D015203:Reproducibility of Results; D012964:Sodium / Q000032:analysis; D013054:Spectrophotometry, Atomic / Q000379:methods*; D013464:Sulfuric Acids / Q000737:chemistry; D014131:Trace Elements / Q000032:analysis*; D015032:Zinc / Q000032:analysis
chemical_list: D000970:Antineoplastic Agents; D013464:Sulfuric Acids; D014131:Trace Elements; D003035:Cobalt; D017942:Nitric Acid; D008345:Manganese; D003300:Copper; D009532:Nickel; D012964:Sodium; D008274:Magnesium; D015032:Zinc; C033158:sulfuric acid; D006851:Hydrochloric Acid; D011188:Potassium; D002118:Calcium