Intestinal metastases in a squamous cell carcinoma arising in mature cystic teratoma of the ovary: a case report.
Metastatic spread to the intestines by squamous cell carcinoma (SCC) arising in mature cystic teratoma (MCT) or dermoid cyst is a very rare event. A case of a 40-year-old cachectic woman is presented with an MCT of the left ovary found at autopsy. Focal mural thickening of the cyst wall harbored a moderately differentiated SCC with single cell keratinization. Intramural metastases were noted in the jejunum, ileum, colon transversum, and left colonic flexure. In addition, liver metastases were detected. The tumor was staged as FIGO IV. The peritoneum was covered diffusely by fibrinous and suppurative exudate. In this unusual case, metastasizing SCC of the ovary arising in an MCT led to suppurative peritonitis and consequently to death of the patient. Follow-up procedures regarding intestinal spread could be useful in patients with SCC in MCT.
Brustmann
Hermann
H
Department of Pathology, Thermenklinikum, A-2340 Moedling/Vienna, Austria. ddrbrustmann@hotmail.com
D000328:Adult; D002294:Carcinoma, Squamous Cell / Q000150:complications / Q000556:secondary*; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007414:Intestinal Neoplasms / Q000150:complications / Q000556:secondary*; D010051:Ovarian Neoplasms / Q000150:complications / Q000473:pathology*; D010538:Peritonitis / Q000209:etiology / Q000473:pathology; D017697:Premenopause; D013724:Teratoma / Q000150:complications / Q000556:secondary*