[The pro-inflammatory role of cytokines in the mechanism of atherosclerosis].
Investigation of the mechanisms of atherosclerosis has determined that inflammation plays a central role in the development, progression, and outcome of acute coronary syndrome. Although C-reactive protein will remain over time a useful marker, cytokines will continue to be studied in order to understand the mechanisms of acute coronary syndrome and cytokine balance. This short review summarizes the experimental and clinical evidence regarding the role of some cytokines in acute coronary syndrome (interleukin [IL]-8, IL-10, IL-18, IL-2, tumor necrosis factor-alpha, interferon-gamma).
Correale
Michele
M
Dipartimento di Cardiologia, Università degli Studi, Foggia. opsfco@tin.it
Brunetti
Natale Daniele
ND
Di Biase
Matteo
M
D000208:Acute Disease; D000789:Angina, Unstable / Q000276:immunology; D050197:Atherosclerosis / Q000209:etiology* / Q000276:immunology; D016207:Cytokines / Q000276:immunology*; D006801:Humans; D007249:Inflammation / Q000150:complications; D009203:Myocardial Infarction / Q000276:immunology; D013577:Syndrome
D016207:Cytokines