[Clinicopathologic study of ischemic intestinal disease due to mesenteric venous lesions].
OBJECTIVE
To study the clinical and pathologic features of ischemic intestinal disease due to mesenteric phlebitis.


METHODS
The clinical and pathologic features of the mesenteric venous lesions in 3 patients of ischemic intestinal disease admitted during the period from 2003 to 2004 were studied.


RESULTS
All 3 patients had a clinical history of acute abdominal pain accompanying with a diffuse peritonitis. During operation, an infarcted intestinal segment was identified and was resected respectively in each patient. Histologic examination showed a lymphocytic infiltration and fibrinoid necrosis of the small to medium-sized veins, associated with mural thrombosis and infarction of the corresponding intestinal wall and mesentery. The mesenteric arteries were spared. Two-year follow up of one case showed no evidence of local recurrence or systemic vasculitis.


CONCLUSIONS
Ischemic intestinal disease due to mesenteric phlebitis is a rare entity with a pathological feature of inflammation of venous wall accompanying with the development of mural thrombosis and subsequent haemorrhagic infarction of intestine. The etiology is unknown and surgical resection of the involved intestinal segment is usually recommended.
Wang
Li-feng
LF
Department of Pathology, First Hospital of Harbin Medical University, Harbin 150001, China. lfwy@public.hr.hl.cn
Liu
Ming
M
Zhang
Shu-jie
SJ
Han
Wei
W
Gao
Feng
F
Qi
Ji-ping
JP
D000328:Adult; D000368:Aged; D017091:Colitis, Ischemic / Q000209:etiology / Q000473:pathology / Q000601:surgery; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007410:Intestinal Diseases / Q000209:etiology / Q000473:pathology* / Q000601:surgery; D007421:Intestine, Small / Q000098:blood supply / Q000473:pathology* / Q000601:surgery; D007511:Ischemia / Q000150:complications; D008297:Male; D008641:Mesenteric Vascular Occlusion / Q000150:complications*; D008642:Mesenteric Veins / Q000473:pathology*; D008875:Middle Aged; D010689:Phlebitis / Q000150:complications