title: Timing of thoracic and lumbar fracture fixation in spinal injuries: a systematic review of neurological and clinical outcome.
abstract: A systematic review of all available evidence on the timing of surgical fixation for thoracic and lumbar fractures with respect to clinical and neurological outcome was designed. The purpose of this review is to clarify some of the controversy about the timing of surgical fracture fixation in spinal trauma. Better neurological outcome, shorter hospital stay and fewer complications have been reported after early fracture fixation. But there are also studies showing no difference in neurological outcome when compared to late treatment. Mortality is another controversial point since a recent report of higher mortality in early treated patients. A systematic review of the literature was preformed. Ten articles were included. Early fracture fixation is associated with less complications, shorter hospital and ICU stay. The effect of early treatment on the neurological outcome remains unclear due to the contradictory results of the included studies. Early thoracic and lumbar fracture fixation results in improvement of clinical outcome, but the effect on neurological outcome remains controversial.
authors.affiliation: Department of Orthopaedic Surgery, University Medical Centre Utrecht, Heidelberglaan 100, Utrecht, 3584 CX, The Netherlands. j.rutges@umcutrecht.nl
authors.forename: Jozef Paulus Henricus Johannes
authors.initials: JP
authors.lastname: Rutges
authors.forename: F Cumhur
authors.initials: FC
authors.lastname: Oner
authors.forename: Luke Peter Hendrik
authors.initials: LP
authors.lastname: Leenen
mesh_terms: D005593:Fracture Fixation, Internal; D006801:Humans; D008159:Lumbar Vertebrae / Q000293:injuries* / Q000601:surgery; D016103:Spinal Fractures / Q000601:surgery*; D013904:Thoracic Vertebrae / Q000293:injuries* / Q000601:surgery; D013997:Time Factors; D016896:Treatment Outcome