title: New synthetic protocols for the preparation of unsymmetrical bisindoles.
abstract: Novel unsymmetrical bisindoles were synthesized by a solvent-free C-C bond-formation reaction under mild conditions. Starting from aziridines or hydroxyl precursors, indoles have been used as C-nucleophiles to form new pharmacologically interesting bisindoles via an electrophilic aromatic substitution pathway in good to excellent yields. [reaction: see text]
authors.affiliation: Leibniz-Institut für Katalyse e.V. an der Universität Rostock, Albert-Einstein-Strasse 29a, D-18059 Rostock, Germany.
authors.forename: Hanns Martin
authors.initials: HM
authors.lastname: Kaiser
authors.forename: Wei Fun
authors.initials: WF
authors.lastname: Lo
authors.forename: Abdol Majid
authors.initials: AM
authors.lastname: Riahi
authors.forename: Anke
authors.initials: A
authors.lastname: Spannenberg
authors.forename: Matthias
authors.initials: M
authors.lastname: Beller
authors.forename: Man Kin
authors.initials: MK
authors.lastname: Tse
mesh_terms: D001388:Aziridines / Q000737:chemistry; D002384:Catalysis; D003460:Crystallization; D018360:Crystallography, X-Ray; D017665:Hydroxyl Radical; D007211:Indoles / Q000138:chemical synthesis* / Q000737:chemistry; D019311:Staurosporine / Q000737:chemistry
chemical_list: D001388:Aziridines; D007211:Indoles; D017665:Hydroxyl Radical; D019311:Staurosporine