title: Pulmonary hypertension and patent ductus arteriosus in an 82-year-old female patient.
abstract: An 82-year-old female patient with a history of deep vein thrombosis presented with progressive dyspnea. Echocardiogram demonstrated significant pulmonary hypertension and patent ductus arteriosus (PDA). There was considerable debate regarding the role of PDA in the patient's pulmonary hypertension. The patient died of heart failure a few months later. Autopsy demonstrated extensive chronic pulmonary thromboembolic disease. Pulmonary thromboemboli continue to be a diagnostic challenge despite modern diagnostic modalities. Autopsy continues to play a role in investigating unexplained clinical findings and in determining cause of death.
authors.affiliation: Division of Anatomical Pathology, Department of Laboratory Medicine, Ottawa Hospital, Ottawa, Ontario, Canada.
authors.forename: Manisha
authors.initials: M
authors.lastname: Lamba
authors.forename: Luc M
authors.initials: LM
authors.lastname: Beauchesne
authors.forename: John P
authors.initials: JP
authors.lastname: Veinot
mesh_terms: D000369:Aged, 80 and over; D000925:Anticoagulants / Q000627:therapeutic use; D004374:Ductus Arteriosus, Patent / Q000150:complications / Q000473:pathology*; D004417:Dyspnea / Q000209:etiology / Q000473:pathology; D004452:Echocardiography; D017809:Fatal Outcome; D005260:Female; D006333:Heart Failure / Q000209:etiology / Q000473:pathology; D006801:Humans; D006976:Hypertension, Pulmonary / Q000209:etiology / Q000473:pathology* / Q000628:therapy; D010102:Oxygen Inhalation Therapy; D011655:Pulmonary Embolism / Q000150:complications / Q000473:pathology / Q000628:therapy
chemical_list: D000925:Anticoagulants