Diabetic nephropathy: worldwide epidemic and effects of current treatment on natural history.
Diabetic nephropathy has become a worldwide epidemic, accounting for approximately one third of all cases of end-stage renal disease. With increasing prevalence of diabetes particularly in Asia, and a global prevalence of microalbuminuria of 39%, the problem is expected to grow. Improved management of diabetes aimed at improved glycemic control, to avoid initiation of diabetic nephropathy, and antihypertensive treatment blocking the renin-angiotensin system, to avoid its progression, need to be implemented, particularly in high-risk patients.
Rossing
Peter
P
Steno Diabetes Center, Niels Steensens Vej 2, DK 2820 Gentofte, Denmark. pro@steno.dk
D000959:Antihypertensive Agents / Q000627:therapeutic use; D003922:Diabetes Mellitus, Type 1 / Q000503:physiopathology; D003924:Diabetes Mellitus, Type 2 / Q000503:physiopathology; D003928:Diabetic Nephropathies / Q000453:epidemiology* / Q000503:physiopathology / Q000628:therapy; D006801:Humans; D006943:Hyperglycemia / Q000517:prevention & control; D015994:Incidence; D007676:Kidney Failure, Chronic / Q000453:epidemiology
D000959:Antihypertensive Agents