Lobar pneumonia caused by nontyphoidal Salmonella in a Malawian child.
Nontyphoidal Salmonella (NTS) is recognized as a common cause of bacteremia in malaria-endemic Africa but its importance as a cause of pneumonia is uncertain. We report a case of pneumonia caused by NTS confirmed by culture of lung aspirate from a consolidated left lung in a 16 month-old HIV-uninfected girl who had been admitted to the hospital 1 month previously with severe malaria. She did not respond to first-line antibiotic therapy for benzylpenicillin and gentamicin but improved with ceftriaxone therapy.
Mankhambo
Limangeni A
LA
Malawi-Liverpool-Wellcome Trust Programme of Clinical Tropical Research and Department of Paediatrics, College of Medicine, Blantyre, Malawi.
Chiwaya
Kwame W
KW
Phiri
Agib
A
Graham
Stephen M
SM
D000900:Anti-Bacterial Agents / Q000494:pharmacology / Q000627:therapeutic use; D002443:Ceftriaxone / Q000494:pharmacology / Q000627:therapeutic use; D005260:Female; D005839:Gentamicins / Q000494:pharmacology / Q000627:therapeutic use; D015658:HIV Infections / Q000150:complications; D006760:Hospitalization; D006801:Humans; D007223:Infant; D008168:Lung / Q000382:microbiology; D008288:Malaria / Q000150:complications; D008295:Malawi; D010400:Penicillin G / Q000494:pharmacology / Q000627:therapeutic use; D018410:Pneumonia, Bacterial / Q000188:drug therapy / Q000382:microbiology*; D012475:Salmonella / Q000302:isolation & purification*; D012480:Salmonella Infections / Q000188:drug therapy / Q000382:microbiology*
D000900:Anti-Bacterial Agents; D005839:Gentamicins; D002443:Ceftriaxone; D010400:Penicillin G