title: Solitary, late metastatic recurrence of renal cell carcinoma: two extraordinary cases.
abstract: Late recurrence of renal cell carcinoma (RCC) has been well documented in the literature. We present two extraordinary cases of solitary, late metastatic recurrence of RCC. The first is a case of a solitary, adrenal metastasis excised 38 years after nephrectomy and the second is a case in which two solitary metastatic deposits were resected 14 and 26 years after excision of the primary tumor. In each of these patients the solitary metastases were initially believed to be primary tumors at other sites; however, on histological examination they were found to be metastatic RCC recurrences. In patients with a previous history of RCC presenting with apparently new solitary lesions, metastatic RCC must first be excluded.
authors.affiliation: Department of Urology, Southampton University Hospitals National Health Services Trust, Southampton, Hampshire, UK. jonfeath@aol.com
authors.forename: Jonathan M
authors.initials: JM
authors.lastname: Featherstone
authors.forename: Paul
authors.initials: P
authors.lastname: Bass
authors.forename: John
authors.initials: J
authors.lastname: Cumming
authors.forename: Christopher J
authors.initials: CJ
authors.lastname: Smart
mesh_terms: D000328:Adult; D000368:Aged; D002292:Carcinoma, Renal Cell / Q000175:diagnosis / Q000556:secondary* / Q000601:surgery; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007680:Kidney Neoplasms / Q000473:pathology* / Q000601:surgery; D008297:Male; D009362:Neoplasm Metastasis; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis / Q000556:secondary* / Q000601:surgery; D009392:Nephrectomy; D013997:Time Factors; D014057:Tomography, X-Ray Computed