Changes within the thyroid axis during the course of critical illness.
This article reviews the mechanisms behind the observed changes in plasma thyroid hormone levels in the acute phase and the prolonged phase of critical illness. It focuses on the neuroendocrinology of the low triiodothyronine syndrome and on thyroid hormone metabolism by deiodination and transport.
Mebis
Liese
L
Department of Intensive Care, Catholic University of Leuven, Leuven, Belgium.
Debaveye
Yves
Y
Visser
Theo J
TJ
Van den Berghe
Greet
G
D003422:Critical Care / Q000379:methods; D016638:Critical Illness / Q000628:therapy; D006801:Humans; D007030:Hypothalamo-Hypophyseal System / Q000503:physiopathology*; D010913:Pituitary-Adrenal System / Q000503:physiopathology*; D013961:Thyroid Gland / Q000503:physiopathology*; D013963:Thyroid Hormones / Q000502:physiology
D013963:Thyroid Hormones