title: [Clinical characteristics of 143 Chinese HIV/AIDS patients].
abstract: OBJECTIVE
  To investigate the clinical characteristics of human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS) patients in China.
  
  
  METHODS
  Totally 143 HIV/AIDS patients who were first diagnosed in Peking Union Medical College Hospital form January 1988 to April 2006 were enrolled in this study. Clinical characteristics were retrospectively analyzed.
  
  
  RESULTS
  Among 143 HIV/ AIDS patients, 57 patients had no clinical symptoms and were confirmed by routine examinations; 86 patients had clinical symptoms, including fever (n = 50), weight loss (n = 18), and discomforts involving respiratory system (n = 34), gastrointestinal system (n = 16), and derma and mucosa (n = 17). Opportunistic infections (OIs) such as pneumocystis jiroveci pneumonia (PCP) (n = 27), oropharyngeal candidiasis (n = 16), tuberculosis (n = 15) , and cytomegalovirus (CMV) infection (n = 9) were also observed in patients whose CD4 + T cell counts were less than 200/mm3. Most CMV infection and cryptococcal meningitis occurred in patients whose CD4 + T cell counts were less than 100/mm3. CD4 + T cell count was negatively correlated with plasma viral load (r = -0.420, P = 0.001).
  
  
  CONCLUSIONS
  Fever, dyspnea, and weight loss are the most common symptoms in the patients of this study. The respiratory system, gastrointestinal system, derma and mucosa are the most commonly affected areas by OIs, and PCP is the most common OI. The occurrence of OIs corelates with CD4 + T cell count.
authors.affiliation: Department of Infectious Diseases, PUMC Hospital, CAMS and PUMC, Beijing 100730, China.
authors.forename: Yi
authors.initials: Y
authors.lastname: Dai
authors.forename: Tai-sheng
authors.initials: TS
authors.lastname: Li
authors.forename: Ai-xia
authors.initials: AX
authors.lastname: Wang
authors.forename: Zhi-feng
authors.initials: ZF
authors.lastname: Qiu
authors.forename: Jing
authors.initials: J
authors.lastname: Xie
authors.forename: Yang
authors.initials: Y
authors.lastname: Han
authors.forename: Zheng-yin
authors.initials: ZY
authors.lastname: Liu
authors.forename: Xiao-jun
authors.initials: XJ
authors.lastname: Ma
authors.forename: Huan-ling
authors.initials: HL
authors.lastname: Wang
authors.forename: Hong-wei
authors.initials: HW
authors.lastname: Fan
authors.forename: Ling-yan
authors.initials: LY
authors.lastname: Zuo
authors.forename: Yan-ling
authors.initials: YL
authors.lastname: Li
authors.forename: Guo-hua
authors.initials: GH
authors.lastname: Deng
authors.forename: Rui-yuan
authors.initials: RY
authors.lastname: Sheng
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000276:immunology; D000163:Acquired Immunodeficiency Syndrome / Q000150:complications*; D000293:Adolescent; D000328:Adult; D000368:Aged; D018791:CD4 Lymphocyte Count; D002681:China; D004417:Dyspnea / Q000209:etiology; D004614:Emaciation / Q000209:etiology; D005260:Female; D005334:Fever / Q000209:etiology; D015658:HIV Infections / Q000150:complications*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011020:Pneumonia, Pneumocystis / Q000276:immunology; D012189:Retrospective Studies