title: The role of acrylophosphonic acid monomers in the formation of hybrid layers based on self-etch adhesives.
abstract: The role of acrylophosphonic acid monomers in the formation of hybrid layers based on self-etch adhesives.
  
  
  OBJECTIVE
  Our plan was to define the reaction products formed when an acrylophosphonic acid reacts with tooth hard tissue. Our aim was to describe the incorporation of the reaction products in the hybrid layer formed.
  
  
  METHODS
  Potentiometric methods were used to measure acid dissociation constants and investigate calcium complex formation. Infrared spectroscopy and NMR were used to follow water contents and show transformation of phosphorous containing compounds.
  
  
  RESULTS
  The acrylophosphonic acid contained in AdheSE (Ivoclar Vivadent, Schaan, Liechtenstein) is characterized by two acidities with pK(a1)=2.4 and pK(a2)=7.0, and interacts with calcium ions in a purely ionic fashion. When hydroxyapatite crystals are dissociated by the presence of AdheSE, brushite is formed together with a calcium cross-linked network of the phosphonate containing copolymer.
  
  
  CONCLUSIONS
  The results give a new image of the hybrid layer where the adhesive behaves like an ionomer resin incorporating collagen but also minerals and salt bridges.
authors.affiliation: Department of Biomaterials, Faculty of Odontology, University Toulouse III, 3 Chemin des Maraîchers, 31062 Toulouse, Cedex 4, France.
authors.forename: Marie A
authors.initials: MA
authors.lastname: Bayle
authors.forename: Geneviève
authors.initials: G
authors.lastname: Grégoire
authors.forename: Patrick
authors.initials: P
authors.lastname: Sharrock
mesh_terms: D000134:Acid Etching, Dental; D000180:Acrylic Resins / Q000737:chemistry*; D003804:Dentin / Q000737:chemistry; D003806:Dentin Permeability; D017220:Dentin-Bonding Agents / Q000737:chemistry*; D024022:Fibrillar Collagens / Q000737:chemistry; D006801:Humans; D006882:Hydroxyapatites / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D008964:Molar, Third; D063065:Organophosphonates / Q000737:chemistry*; D044367:Phase Transition; D011199:Potentiometry; D019279:Resin Cements / Q000737:chemistry*; D017550:Spectroscopy, Fourier Transform Infrared
chemical_list: D000180:Acrylic Resins; C489662:AdheSE cement; D017220:Dentin-Bonding Agents; D024022:Fibrillar Collagens; D006882:Hydroxyapatites; D063065:Organophosphonates; D019279:Resin Cements