A new cerebroside from fruits of Ailanthus altissima Swingle.
A new cerebroside and three known cycloartan triterpenes were isolated from fruits of Ailanthus altissima Swingle. Their structures were identified as 1-O-beta-D-glucopyranosyl-(2S, 3R, 4E, 9E)-2-(2'R-hydroxyhexadecenoy)-4, 9-octadecadiene-1, 3-diol (1), 9, 19-cyclolanost-23 (Z)-ene-3beta, 25-diol (2), cycloart-25-ene-3beta, 24R-diol (3), and cycloart-25-ene-3beta, 24S-diol (4) by means of chemical and spectroscopic analysis. Compounds 2, 3, and 4 were isolated from genus Ailanthus for the first time. The analgesic activity of 1 was also evaluated.
Zhao
Chun-Chao
CC
Research Department of Natural Medicine, Shenyang Pharmaceutical University, Shenyang 110016, China.
Shao
Jian-Hua
JH
Wang
Nan
N
Li
Xian
X
Wang
Jin-Hui
JH
D032268:Ailanthus / Q000737:chemistry*; D000700:Analgesics / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D000818:Animals; D001681:Biological Assay; D002554:Cerebrosides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D002681:China; D005638:Fruit / Q000737:chemistry; D051379:Mice; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D009904:Optical Rotation; D021241:Spectrometry, Mass, Electrospray Ionization
D000700:Analgesics; D002554:Cerebrosides