[Clinical research on effects of yunpi zhixie granule in children with diarrhea].
OBJECTIVE
To investigate the clinical effect of Yunpi Zhixie Granule (YZG) on children's diarrhea.


METHODS
Three hundred diarrhea cases were randomly divided into two groups equally, the treated group treated by YZG orally and the control group by smacta, both for 7 days. The clinical efficacy was observed, routine scatologic analysis, scatologic cultivation, rotavirus antigen and urinary D-xylose content were detected.


RESULTS
Clinical results showed the effective rate in treating the chronic or Pi-deficiency diarrhea as well as the negative conversion rate and improvement rate of routine scatologic analysis were all higher in the treated group than those in the control group (P < 0.05); while no significant difference was found in negative conversion rate of scatologic cultivation and rotavirus antigen and urinary D-xylose content after treatment, compared with those before treatment (P > 0.05).


CONCLUSIONS
YZG was effective in treating children' s diarrhea, especially on chronic diarrhea and diarrhea of Pi-deficiency type.
Yang
Yan
Y
Beijing Children's Hospital Affiliated to Capital University of Medical Sciences, Beijing. yy2303@sina.com
Yan
Hui-min
HM
D000284:Administration, Oral; D002648:Child; D002675:Child, Preschool; D003967:Diarrhea / Q000188:drug therapy*; D003968:Diarrhea, Infantile / Q000188:drug therapy / Q000652:urine; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008517:Phytotherapy; D016896:Treatment Outcome; D014994:Xylose / Q000652:urine
D004365:Drugs, Chinese Herbal; C526708:yunpi zhixie; D014994:Xylose