title: Human papillomavirus DNA in triple neoplasms of the cervix, perianus and ureter in one woman.
abstract: BACKGROUND
  Multiple malignancies of the urogenital tract have been reported. We investigated the etiological role of human papillomavirus (HPV) in the pathogenesis of urogenital cancers.
  
  
  METHODS
  We present a case of cervical squamous carcinoma in a 64-year-old woman who subsequently developed Bowen's disease in the perianal skin and transitional cell carcinoma of the ureter. HPV DNA was detected in these tumor specimens using polymerase chain reaction.
  
  
  CONCLUSIONS
  The results strongly suggest that HPV may play a major role in the carcinogenesis of urogenital and perianal tumors.
authors.affiliation: Department of Obstetrics and Gynecology, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan, ROC. m002057@ms.skh.org.tw
authors.forename: Lee-Wen
authors.initials: LW
authors.lastname: Huang
authors.forename: Hun-Shan
authors.initials: HS
authors.lastname: Pan
authors.forename: Yu-Hung
authors.initials: YH
authors.lastname: Lin
authors.forename: Kuang-Yu
authors.initials: KY
authors.lastname: Chou
mesh_terms: D002294:Carcinoma, Squamous Cell / Q000453:epidemiology / Q000473:pathology / Q000821:virology*; D002295:Carcinoma, Transitional Cell / Q000453:epidemiology / Q000473:pathology / Q000821:virology*; D004279:DNA, Viral / Q000032:analysis; D005260:Female; D006801:Humans; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary; D027383:Papillomaviridae; D030361:Papillomavirus Infections / Q000150:complications*; D014516:Ureteral Neoplasms / Q000453:epidemiology / Q000473:pathology / Q000821:virology*; D002583:Uterine Cervical Neoplasms / Q000453:epidemiology / Q000473:pathology / Q000821:virology*
chemical_list: D004279:DNA, Viral