[Influence of testing conditions on the susceptibility results of Staphylococcus cohnii to beta-lactams].
The high occurence of coagulase-negative staphylococci among bacteria responsible for hospital infections is unquestioned. Studies on the poorly-known novobiocin-resistant, coagulase-negative Staphylococcus cohnii were undertaken. The possibilities of optimizing conditions for determination of susceptibility to beta-lactam antibiotics of this species were researched. In the case of S. cohnii the new cefoxitin test for detection of methicillin resistant strains, introduced by the National Reference Centre for Antibiotics in Poland was found as a good and of credible quality. It was also shown, that application in in vitro examination conditions stimulating the mechanisms of resistance to beta-lactam antibiotics, supplies credible results relating to their true susceptibility. The necessity of establishing individual conditions for susceptibility determination in different species of coagulase-negative staphylococci was suggested.
Nowak
Tonmasz
T
Zakład Mikrobiologii Farmaceutycznej, Katedra Biologii i Biotechnologii Farmaceutycznej Uniwersytetu Medycznego w Lodzi. tnowak@pharm.am.lodz.pl
Szewczyk
Eligia M
EM
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D004352:Drug Resistance, Microbial / Q000235:genetics; D006358:Hot Temperature; D006801:Humans; D008826:Microbial Sensitivity Tests; D013210:Staphylococcus / Q000145:classification* / Q000187:drug effects* / Q000235:genetics; D013997:Time Factors; D047090:beta-Lactams / Q000494:pharmacology*
D000900:Anti-Bacterial Agents; D047090:beta-Lactams