Echinococcosis: a possible etiology in psoriatic disease.
We aimed to investigate seroprevalence of Echinococcus granulosus in patients with psoriasis to determine a possible etiologic role, since both echinococcosis and psoriasis are defined as T cell-mediated diseases. Forty psoriatic patients and 50 age- and sex-matched control subjects were included in the study. IgG-specific ELISA was used to determine seropositivity. E. granulosus-specific IgG antibodies were found to be positive in 17/40 (42.5%) of the patients with psoriasis and in 11/50 (22%) of the control subjects (p = 0.008). Our results suggest that echinococcosis might be one of the causative pathogens in the etiopathogenesis of psoriasis in highly endemic regions.
Apan
Teoman Zafer
TZ
Department of Microbiology, Kirikkale University Faculty of Medicine, Kirikkale, Turkey. teomanapan@yahoo.com
Kaygusuz
Sedat
S
D000328:Adult; D000368:Aged; D000818:Animals; D000909:Antibodies, Helminth / Q000097:blood; D016022:Case-Control Studies; D004443:Echinococcosis / Q000150:complications* / Q000276:immunology; D048209:Echinococcus granulosus / Q000276:immunology / Q000302:isolation & purification*; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D008297:Male; D008875:Middle Aged; D011565:Psoriasis / Q000276:immunology / Q000469:parasitology*; D016036:Seroepidemiologic Studies
D000909:Antibodies, Helminth; D007074:Immunoglobulin G