Upregulation of IL-6, IL-8, CXCL1, and CXCL2 dominates gene expression in human fibroblast cells exposed to Loxosceles reclusa sphingomyelinase D: insights into spider venom dermonecrosis.
Dragulev
Bojan
B
Bao
Yongde
Y
Ramos-Cerrillo
Blanca
B
Vazquez
Hilda
H
Olvera
Alejandro
A
Stock
Roberto
R
Algaron
Alejandro
A
Fox
Jay W
JW
D002478:Cells, Cultured; D054360:Chemokine CXCL1; D054426:Chemokine CXCL2; D019743:Chemokines, CXC / Q000235:genetics / Q000378:metabolism*; D005347:Fibroblasts / Q000378:metabolism* / Q000473:pathology; D005786:Gene Expression Regulation / Q000187:drug effects; D006801:Humans; D015850:Interleukin-6 / Q000235:genetics / Q000378:metabolism*; D016209:Interleukin-8 / Q000235:genetics / Q000378:metabolism*; D009336:Necrosis / Q000209:etiology / Q000473:pathology; D010727:Phosphoric Diester Hydrolases / Q000494:pharmacology*; D013111:Spider Venoms / Q000201:enzymology*; D015854:Up-Regulation / Q000187:drug effects
C475829:CXCL1 protein, human; C499706:CXCL2 protein, human; D054360:Chemokine CXCL1; D054426:Chemokine CXCL2; D019743:Chemokines, CXC; D015850:Interleukin-6; D016209:Interleukin-8; D013111:Spider Venoms; C055161:loxosceles venom; D010727:Phosphoric Diester Hydrolases; C055160:sphingomyelin phosphodiesterase D