[Pulmonary arterial hypertension following pulmonary thromboembolism].
Chronic thromboembolic pulmonary hypertension is one of the most common forms of pulmonary hypertension (PHT), but frequently remains undiagnosed and untreated. Pulmonary thrombendarterectomy is the treatment of choice, but only about 50 % of such patients are operable. About 15 % of patients are not improved by surgery, usually because of residual PHT with advanced vascular changes. Drug treatment has favorable effects in inoperable forms and in postoperative recurrence of PHT.
Wilkens
H
H
Innere Medizin V-Pneumologie, Universitätsklinikum des Saarlandes, Kirrbergstrasse 1, 66421 Homburg/Saar.
D000959:Antihypertensive Agents / Q000627:therapeutic use; D000077300:Bosentan; D004691:Endarterectomy; D006801:Humans; D006976:Hypertension, Pulmonary / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D016285:Iloprost / Q000627:therapeutic use; D010879:Piperazines / Q000627:therapeutic use; D011655:Pulmonary Embolism / Q000150:complications* / Q000503:physiopathology; D011687:Purines / Q000627:therapeutic use; D012008:Recurrence; D000068677:Sildenafil Citrate; D013156:Splenectomy / Q000009:adverse effects; D013449:Sulfonamides / Q000627:therapeutic use; D013450:Sulfones / Q000627:therapeutic use; D014665:Vasodilator Agents / Q000627:therapeutic use
D000959:Antihypertensive Agents; D010879:Piperazines; D011687:Purines; D013449:Sulfonamides; D013450:Sulfones; D014665:Vasodilator Agents; D000068677:Sildenafil Citrate; D016285:Iloprost; D000077300:Bosentan