title: Cases of glioblastoma multiforme metastasizing to spinal cord.
abstract: Cases of glioblastoma multiforme (GBM) metastasizing to the leptomeninx or the intramedullary spine are quite rare and prognoses are relatively poor. We present three cases of GBM with spinal metastasis, one of which also had leptomeningeal dissemination. Three patients with GBM were admitted to our clinic for postoperative radiotherapy after surgery. Leptomeningeal metastasis and dissemination were diagnosed with magnetic resonance imaging. Radiotherapy provided only temporary relief from pain with small improvement in neurological deficit but no survival advantage.
authors.affiliation: Department of Radiation Oncology, Ankara University Faculty of Medicine, Cebeci Hospital, Dikimevi Ankara, Turkey.
authors.forename: Metehan
authors.initials: M
authors.lastname: Karaca
authors.forename: Meltem Nalca
authors.initials: MN
authors.lastname: Andrieu
authors.forename: Ayse
authors.initials: A
authors.lastname: Hicsonmez
authors.forename: Yildiz
authors.initials: Y
authors.lastname: Guney
authors.forename: Cengiz
authors.initials: C
authors.lastname: Kurtman
mesh_terms: D000328:Adult; D000368:Aged; D001932:Brain Neoplasms / Q000473:pathology*; D017809:Fatal Outcome; D005260:Female; D005909:Glioblastoma / Q000556:secondary*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008577:Meningeal Neoplasms / Q000556:secondary*; D013120:Spinal Cord Neoplasms / Q000556:secondary*