[Stochastic computer model of cellular microtubule dynamics].
A computer model of the system of microtubules has been developed to study the mechanisms of action of various factors on this system. The model describes the process of polymerization/depolymerization of microtubules as a set of chemical reactions with certain rate constants using a stochastic approach. Microtubules are visualized in the program field, which makes the model visual. The program imitates the dynamics and structure of the system of cellular microtubules with great, reliability. The parameters generated by the model correlate with the corresponding parameters of microtubules in living cells. We are going to develop this approach to modeling microtubules and similar structures to bring them into a better accord with living systems and to study the influence of various factors on these systems.
Shpil'man
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Nadezhdina
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D003198:Computer Simulation; D006160:Guanosine Triphosphate / Q000378:metabolism; D006868:Hydrolysis; D008870:Microtubules / Q000378:metabolism*; D008954:Models, Biological; D013269:Stochastic Processes; D014404:Tubulin / Q000378:metabolism
D014404:Tubulin; D006160:Guanosine Triphosphate