title: MINT: the Molecular INTeraction database.
abstract: The Molecular INTeraction database (MINT, http://mint.bio.uniroma2.it/mint/) aims at storing, in a structured format, information about molecular interactions (MIs) by extracting experimental details from work published in peer-reviewed journals. At present the MINT team focuses the curation work on physical interactions between proteins. Genetic or computationally inferred interactions are not included in the database. Over the past four years MINT has undergone extensive revision. The new version of MINT is based on a completely remodeled database structure, which offers more efficient data exploration and analysis, and is characterized by entries with a richer annotation. Over the past few years the number of curated physical interactions has soared to over 95 000. The whole dataset can be freely accessed online in both interactive and batch modes through web-based interfaces and an FTP server. MINT now includes, as an integrated addition, HomoMINT, a database of interactions between human proteins inferred from experiments with ortholog proteins in model organisms (http://mint.bio.uniroma2.it/mint/).
authors.affiliation: Department of Biology, University of Rome Tor Vergata, Via della Ricerca Scientifica, 00133 Rome, Italy.
authors.forename: Andrew
authors.initials: A
authors.lastname: Chatr-aryamontri
authors.forename: Arnaud
authors.initials: A
authors.lastname: Ceol
authors.forename: Luisa Montecchi
authors.initials: LM
authors.lastname: Palazzi
authors.forename: Giuliano
authors.initials: G
authors.lastname: Nardelli
authors.forename: Maria Victoria
authors.initials: MV
authors.lastname: Schneider
authors.forename: Luisa
authors.initials: L
authors.lastname: Castagnoli
authors.forename: Gianni
authors.initials: G
authors.lastname: Cesareni
mesh_terms: D000818:Animals; D030562:Databases, Protein; D006801:Humans; D020407:Internet; D046912:Multiprotein Complexes / Q000737:chemistry; D025941:Protein Interaction Mapping; D014584:User-Computer Interface
chemical_list: D046912:Multiprotein Complexes