title: Effect of Cha-em Thai mouthwash on salivary levels of mutans streptococci and total IgA.
abstract: The aim of this study was to investigate the effect of Cha-em Thai (Albizia myriophylla) mouthwash on the mutans streptococci (MS) and immunoglobulin A (IgA) level in saliva. Sixty-seven schoolchildren, age 6-12 years, with MS more than 1x10(5) cfu per milliliter of saliva were entered in this study. They were divided into two balanced groups according to their baseline MS counts (> or = 10(5) cfu/ml). Each group was randomly assigned to use either the Cha-em Thai mouthwash or the placebo mouthwash. After twice daily rinses with their mouthwash for 2 weeks, stimulated saliva were collected and analysed. The MS counts and IgA levels for the two groups were compared. Those rinsing with Cha-em Thai mouthwash showed a significant reduction in MS counts (p<0.05), but the IgA levels were not different. Those rinsing with the placebo mouthwash showed no statistically significant differences in the MS counts or the IgA levels (p>0.05). The results indicate that twice daily use of Cha-em Thai mouthwash can reduce the levels of MS in saliva.
authors.affiliation: Cholticha Amornchat, Department of Microbiology, Faculty of Dentistry, Mahidol University, 6 Yothi Road, Bangkok 10400, Thailand. dtcam@mahidol.ac.th
authors.forename: Cholticha
authors.initials: C
authors.lastname: Amornchat
authors.forename: Petcharat
authors.initials: P
authors.lastname: Kraivaphan
authors.forename: Chuchote
authors.initials: C
authors.lastname: Dhanabhumi
authors.forename: Kalaya
authors.initials: K
authors.lastname: Tandhachoon
authors.forename: Terdphong
authors.initials: T
authors.lastname: Trirattana
authors.forename: Suwan
authors.initials: S
authors.lastname: Choonhareongdej
mesh_terms: D031289:Albizzia; D002648:Child; D006801:Humans; D007070:Immunoglobulin A / Q000187:drug effects* / Q000302:isolation & purification; D009067:Mouthwashes / Q000494:pharmacology*; D028321:Plant Preparations / Q000494:pharmacology*; D018547:Plant Stems; D012463:Saliva / Q000187:drug effects / Q000382:microbiology*; D013295:Streptococcus mutans / Q000187:drug effects* / Q000302:isolation & purification
chemical_list: D007070:Immunoglobulin A; D009067:Mouthwashes; D028321:Plant Preparations