Amberlite IRA900N3 as a new catalyst for the azidation of alpha,beta-unsaturated ketones under solvent-free conditions.
Amberlite IRA900N3 is an excellent organocatalyst for the azidation of alpha,beta-unsaturated ketones with trimethylsilyl azide under solvent-free conditions. By avoiding the use of metallic species and of the organic reaction medium, the procedure is a green tool for the preparation of beta-azido ketones under mild conditions with yields from good to excellent. The catalyst can be recovered and re-used with no loss of its efficiency.
Castrica
Luca
L
CEMIN-Dipartimento di Chimica, Università di Perugia, Via Elce di Sotto, 8, I-06123 Perugia, Italy.
Fringuelli
Francesco
F
Gregoli
Luisa
L
Pizzo
Ferdinando
F
Vaccaro
Luigi
L
D001386:Azides / Q000737:chemistry*; D002384:Catalysis; D007659:Ketones / Q000737:chemistry*; D012997:Solvents / Q000737:chemistry
D001386:Azides; D007659:Ketones; D012997:Solvents