Clinicopathological analysis of histological variants of ameloblastoma in a suburban Nigerian population.
BACKGROUND
This study was carried out to establish the relative incidence and provide clinico-pathologic information on the various histological types of ameloblastoma seen at the Obafemi Awolowo University Teaching Hospital complex, Ile-Ife in order to provide a baseline data which will be of significance to the pathologist and clinician.


METHODS
Clinico-pathologic data on a total of 77 histologically diagnosed cases of ameloblastoma archieved at the Obafemi Awolowo University Teaching Hospital Complex, Ile-Ife over a 15 year period were obtained and analysed descriptively.


RESULTS
Follicular ameloblastoma was the most common histological type (50 cases, 64.9%), followed by plexiform ameloblastoma (10 cases, 13.0%). 4 (5.2%) cases of desmoplastic and 3 (3.9%) cases of acanthomatous ameloblastoma were seen while the basal cell variant accounted for 2 (2.6%) cases. Only 1 case of the unicystic type was seen. Some of the 77 cases presented as a mixture of two or more histological types. Ameloblastoma occurred over an age range of 11 to 70 years with a peak age incidence in the 3rd decade.


CONCLUSIONS
This study provides a baseline data on variants of ameloblastoma as obtained in a suburban Nigerian population. Since variants of ameloblastoma differ in biologic behaviour, the data collected in this study provides clinicopathologic information which is of significance to the pathologist and clinician.
Adebiyi
Kehinde E
KE
Department of Oral/Maxillofacial Surgery and Oral Pathology, Obafemi Awolowo University, Ile Ife, Nigeria. kenad@justice.com
Ugboko
Vincent I
VI
Omoniyi-Esan
Ganiat O
GO
Ndukwe
Kizito C
KC
Oginni
Fadekemi O
FO
D000293:Adolescent; D000328:Adult; D000368:Aged; D000564:Ameloblastoma / Q000145:classification / Q000453:epidemiology / Q000473:pathology*; D002648:Child; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D015994:Incidence; D007573:Jaw Neoplasms / Q000145:classification / Q000453:epidemiology / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009549:Nigeria / Q000453:epidemiology; D015995:Prevalence; D012189:Retrospective Studies; D013383:Suburban Population; D055815:Young Adult