title: Early reversible ischemia of femoral head epiphysis in piglets on gadolinium-enhanced MRI: an experimental study.
abstract: The purpose of this study is to demonstrate if Gadolinium-enhanced MRI can detect early reversible ischemia of the femoral head epiphysis caused by hip hyper-abduction in piglets. Between 3 and 6 h consistent hyper-abduction, gadolinium-enhanced MRI was performed in 20 femoral heads of 10 piglets. After completion of MRI scan, the piglets were allowed to ambulate freely for 1 or 7 days and re-imaged. The enhanced-MRI results of epiphyseal and physeal cartilage and the secondary center of ossification were observed. MRI appearances and histological findings were compared. On Gadolinium-enhanced MRI, decreased or absent enhancement was seen in 14 cartilaginous epiphyses of all 20 femoral heads. Reperfusion was completed in 10 of 14 femoral heads after one day of ambulation and in the rest 4 after 7 days of ambulation. Gadolinium-enhanced MRI can identify early ischemia and its reversal of the capital femoral epiphysis induced by hip hyper-abduction.
authors.affiliation: Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
authors.forename: Xiaoming
authors.initials: X
authors.lastname: Li
authors.forename: Junwu
authors.initials: J
authors.lastname: Hu
authors.forename: Hongwei
authors.initials: H
authors.lastname: Zhen
authors.forename: Lihua
authors.initials: L
authors.lastname: Tang
authors.forename: Anhui
authors.initials: A
authors.lastname: Xu
mesh_terms: D000818:Animals; D003287:Contrast Media; D004838:Epiphyses / Q000098:blood supply; D005270:Femur Head / Q000098:blood supply* / Q000473:pathology; D005271:Femur Head Necrosis / Q000175:diagnosis; D005682:Gadolinium; D007511:Ischemia / Q000175:diagnosis*; D008279:Magnetic Resonance Imaging / Q000379:methods; D013552:Swine; D013997:Time Factors
chemical_list: D003287:Contrast Media; D005682:Gadolinium