title: Two extreme conditions of xeroderma pigmentosum.
abstract: Two atypical cases of xeroderma pigmentosum are reported. One of these cases with lung metastasis of squamous cell carcinoma in the first decade of life and the other with late onset disease (XP) in fifth decade of life. Lung metastasis of squamous cell carcinoma in first decade of life in patients with xeroderma pigmentosum has never been reported in the literature to our knowledge. Late onset of the disease in fifth decade is also a rare condition. Clinicians should be more alert for the internal organ metastases to improve the survival of the patients and should never forget that xeroderma pigmentosum has got a wide range of clinical presentation.
authors.affiliation: Department of Plastic and Reconstructive Surgery, Ankara Numune Training and Research Hospital, Ankara, Turkey.
authors.forename: Ramazan Erkin
authors.initials: RE
authors.lastname: Unlü
authors.forename: Mustafa Nihat
authors.initials: MN
authors.lastname: Koç
authors.forename: Hakan
authors.initials: H
authors.lastname: Orbay
authors.forename: Omer
authors.initials: O
authors.lastname: Sensöz
mesh_terms: D002294:Carcinoma, Squamous Cell / Q000473:pathology / Q000556:secondary / Q000601:surgery*; D002648:Child; D017809:Fatal Outcome; D005260:Female; D006258:Head and Neck Neoplasms / Q000473:pathology / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009669:Nose Neoplasms / Q000473:pathology / Q000601:surgery*; D012878:Skin Neoplasms / Q000473:pathology / Q000601:surgery*; D013899:Thoracic Neoplasms / Q000556:secondary; D014983:Xeroderma Pigmentosum / Q000150:complications / Q000601:surgery*