[A new triterpenoid saponin from stems of Akebia trifoliata].
OBJECTIVE
To study the chemical constituents of the stems of Akebia trifoliata (Thunb.) Koidz. var. australis (Diels) Rehd.


METHODS
The compounds were isolated and purified by recrystallization and chromatography on silica gel and ODS column. Their structures were elucidated on the basis of physicochemical properties and spectral analysis.


RESULTS
Six compounds were identified as 2 alpha, 3 beta,23-trihydroxyolean-12-en-28-oic acid O-beta-D-xylopyranosyl-(1 --> 3)-O-alpha-L-rhamnopyranosyl-(1 --> 4)-O-beta-D-glucopyranosyl-(1 --> 6)-beta-D-glucopyranosyl ester (I), 2 alpha, 3 beta, 23-trihydroxyurs-12-en-28-oic acid O-beta-D-xylopyranosyl-(1 --> 3)-O-alpha-L-rhamnopyranosyl-(1 --> 4)-O-beta-D-glucopyranosyl-(1 --> 6 )-beta-D-glucopyranosyl ester (II), 2 alpha, 3 beta, 23-trihydroxyolean-12-en-28-oic acid O-alpha-L-rhamnopyranosyl-(1 --> 4)-O-beta-D-glucopyranosyl-(1 --> 6)-beta-D-glucopyranosyl ester (III), 2alpha, 3beta, 23-trihydroxyurs-12-en-28-oic acid O-alpha-L-rhamnopyranosyl-(1 --> 4)-O-beta-D-glucopyranosyl-(1 --> 6)-beta-D-glucopyranosyl ester (IV), 2 alpha, 3 beta, 23-trihydroxyolean-12-en-28-oic acid O-beta-D-glucopyranosyl ester (V), 2 alpha, 3 alpha, 23-trihydroxyurs-12-en-28-oic acid O-beta-D-glucopyranosyl ester (VI).


CONCLUSIONS
Compound II, named mutongsaponin C, is a new triterpenoid saponin and others were isolated from the stems of Akebia trifoliata (Thunb.) Koidz. var. australis (Diels) Rehd for the first time.
Gao
Hui-min
HM
Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China.
Wang
Zhi-min
ZM
D002850:Chromatography, Gel; D003460:Crystallization; D019684:Magnoliopsida / Q000737:chemistry*; D015394:Molecular Structure; D018547:Plant Stems / Q000737:chemistry*; D010946:Plants, Medicinal / Q000737:chemistry; D012503:Saponins / Q000737:chemistry* / Q000302:isolation & purification; D058428:Silica Gel; D012822:Silicon Dioxide; D014315:Triterpenes / Q000737:chemistry* / Q000302:isolation & purification
C526388:2,3,23-trihydroxyurs-12-en-28-oic acid O-xylopyranosyl-1-3-rhamnopyranosyl-1-4-glucopyranosyl-1-6-glucopyranosyl ester; D012503:Saponins; D014315:Triterpenes; D058428:Silica Gel; D012822:Silicon Dioxide