Knocking out the Argonautes.
Argonaute proteins are key players in gene silencing involving small RNAs. In this issue, Yigit et al. (2006) report a comprehensive study of Argonautes in the worm that places many of the 27 family members into a complex gene-silencing network.
Steiner
Florian A
FA
Hubrecht Laboratory-KNAW, Utrecht, 3584 CT, The Netherlands.
Plasterk
Ronald H A
RH
D000818:Animals; D017173:Caenorhabditis elegans / Q000378:metabolism*; D015801:Helminth Proteins / Q000378:metabolism*; D034622:RNA Interference; D020871:RNA Stability
D015801:Helminth Proteins