title: Spinal hemiepiphysiodesis correlates with physeal histomorphometric gradients.
abstract: Compression of a growth plate is known to correlate with changes to growth plate structure. The purpose of this study was to determine if the height of the physeal hypertrophic zones and chondrocyte size were directly related to the distance from a spine implant. The implant was designed with the goal of slowing spine growth asymmetrically. For stapled vertebrae, hypertrophic zone height, cell height and cell width were decreased across the coronal plane of the growth plate, with the lowest values under the staple, 8 weeks postoperatively.
authors.affiliation: Cincinnati Children's Hospital Medical Center and University of Cincinnati, Cincinnati, Ohio 45229-3039, USA.
authors.forename: D I
authors.initials: DI
authors.lastname: Bylski-Austrow
authors.forename: E J
authors.initials: EJ
authors.lastname: Wall
authors.forename: D L
authors.initials: DL
authors.lastname: Glos
authors.forename: E T
authors.initials: ET
authors.lastname: Ballard
authors.forename: K
authors.initials: K
authors.lastname: Stringer
authors.forename: A H
authors.initials: AH
authors.lastname: Crawford
mesh_terms: D001696:Biomechanical Phenomena; D019902:Chondrocytes / Q000166:cytology; D006132:Growth Plate; D006801:Humans; D019736:Prostheses and Implants; D013123:Spinal Fusion / Q000379:methods; D013131:Spine / Q000254:growth & development* / Q000601:surgery; D014481:United States