Amphiphilic poly(N-propargylamide) with galactose and lauryloyl groups: synthesis and properties.
An amphiphilic poly(N-propargylamide) with galactose and lauryloyl groups was synthesized by copolymerization of the corresponding N-propargylamide monomers using a Rh catalyst. The obtained copolymer formed a one-handed helical conformation and molecular aggregates in water. The observations by fluorescence microscopy in a cell culture experiment in the presence of dye-labeled copolymer indicated that the copolymer was incorporated into the cells.
Suenaga
Masakazu
M
Department of Nanostructured and Advanced Materials, Graduate School of Science and Engineering, Kagoshima 890-0065, Japan.
Kaneko
Yoshiro
Y
Kadokawa
Jun-ichi
J
Nishikawa
Takehiro
T
Mori
Hidezo
H
Tabata
Masayoshi
M
D001011:Aorta / Q000166:cytology*; D002478:Cells, Cultured; D016503:Drug Delivery Systems; D042783:Endothelial Cells / Q000166:cytology*; D005690:Galactose / Q000138:chemical synthesis* / Q000494:pharmacology; D006801:Humans; D009757:Nylons / Q000138:chemical synthesis* / Q000494:pharmacology
D009757:Nylons; D005690:Galactose