title: Snap: an integrated SNP annotation platform.
abstract: Snap (Single Nucleotide Polymorphism Annotation Platform) is a server designed to comprehensively analyze single genes and relationships between genes basing on SNPs in the human genome. The aim of the platform is to facilitate the study of SNP finding and analysis within the framework of medical research. Using a user-friendly web interface, genes can be searched by name, description, position, SNP ID or clone name. Several public databases are integrated, including gene information from Ensembl, protein features from Uniprot/SWISS-PROT, Pfam and DAS-CBS. Gene relationships are fetched from BIND, MINT, KEGG and are integrated with ortholog data from TreeFam to extend the current interaction networks. Integrated tools for primer-design and mis-splicing analysis have been developed to facilitate experimental analysis of individual genes with focus on their variation. Snap is available at http://snap.humgen.au.dk/ and at http://snap.genomics.org.cn/.
authors.affiliation: The Institute of Human Genetics, University of Aarhus, DK-8000 Aarhus C, Denmark.
authors.forename: Shengting
authors.initials: S
authors.lastname: Li
authors.forename: Lijia
authors.initials: L
authors.lastname: Ma
authors.forename: Heng
authors.initials: H
authors.lastname: Li
authors.forename: Søren
authors.initials: S
authors.lastname: Vang
authors.forename: Yafeng
authors.initials: Y
authors.lastname: Hu
authors.forename: Lars
authors.initials: L
authors.lastname: Bolund
authors.forename: Jun
authors.initials: J
authors.lastname: Wang
mesh_terms: D030561:Databases, Nucleic Acid; D053263:Gene Regulatory Networks; D015894:Genome, Human; D006801:Humans; D020407:Internet; D020641:Polymorphism, Single Nucleotide; D025941:Protein Interaction Mapping; D011506:Proteins / Q000235:genetics; D018511:Systems Integration; D014584:User-Computer Interface
chemical_list: D011506:Proteins