Lipoprotein(a): a unique risk factor for cardiovascular disease.
Lipoprotein(a) (Lp(a)) is present in humans and primates. It has many properties in common with low-density lipoprotein, but contains a unique protein moiety designated apo(a), which is linked to apolipoprotein B-100 by a single disulfide bond. International standards for Lp(a) measurement and optimized Lp(a) assays insensitive to isoform size are not yet widely available. Lp(a) is a risk factor for coronary artery disease, and smaller size apo(a) is associated with coronary artery disease. The physiologic role of Lp(a) is unknown.
Anuurad
Erdembileg
E
Department of Medicine, VA Northern California Health Care System, UCD Medical Center, University of California-Davis, 4150 V Street, Suite G400, Sacramento, CA 95817, USA.
Boffa
Michael B
MB
Koschinsky
Marlys L
ML
Berglund
Lars
L
D000818:Animals; D050197:Atherosclerosis / Q000097:blood / Q000209:etiology*; D019411:Clinical Laboratory Techniques / Q000379:methods*; D003324:Coronary Artery Disease / Q000097:blood / Q000209:etiology*; D006801:Humans; D007118:Immunoassay; D017270:Lipoprotein(a) / Q000097:blood* / Q000737:chemistry*; D023421:Models, Animal; D012307:Risk Factors
D017270:Lipoprotein(a)