title: One-pot synthesis of 2,3-dihydro-pyrrolopyridinones using in situ generated formimines.
abstract: A novel one-pot methodology is described for the synthesis of functionalized pyrrolopyridinones using in situ generated formimines and an ortho-lithiated pyridinecarboxamide species. Depending on the reaction conditions, this procedure allows versatile access to aminomethylated pyridinecarboxamides, 2,3-dihydro-pyrrolopyridinones, or 1,1-dialkylated 2,3-dihydro-pyrrolopyridinone derivatives. [reaction: see text]
authors.affiliation: Laboratoire de Chimie Organique Fine et Hétérocyclique, IRCOF-INSA Rouen, B.P. 08, 76131 Mont-Saint-Aignan, France.
authors.forename: Geoffrey
authors.initials: G
authors.lastname: Deguest
authors.forename: Alice
authors.initials: A
authors.lastname: Devineau
authors.forename: Laurent
authors.initials: L
authors.lastname: Bischoff
authors.forename: Corinne
authors.initials: C
authors.lastname: Fruit
authors.forename: Francis
authors.initials: F
authors.lastname: Marsais