title: Ru-catalyzed stereoselective addition of imides to alkynes.
abstract: A catalyst system formed in situ from bis(2-methylallyl)cycloocta-1,5-dieneruthenium(II) ((cod)Ru[met]2), a phosphine, and scandium(III) trifluoromethanesulfonate (Sc(OTf)3) was found to efficiently catalyze the anti-Markovnikov addition of imides to terminal alkynes, allowing mild and atom-economic synthesis of enimides. Depending on the phosphine employed, both the (E)- and the (Z)-isomer can be accessed stereoselectively.
authors.affiliation: Institut für Organische Chemie, Technische Universität Kaiserslautern, Erwin-Schrödinger-Strasse, Building 54, D-67663 Kaiserslautern, Germany. goossen@chemie.uni-kl.de
authors.forename: Lukas J
authors.initials: LJ
authors.lastname: Goossen
authors.forename: Mathieu
authors.initials: M
authors.lastname: Blanchot
authors.forename: Claus
authors.initials: C
authors.lastname: Brinkmann
authors.forename: Käthe
authors.initials: K
authors.lastname: Goossen
authors.forename: Ralph
authors.initials: R
authors.lastname: Karch
authors.forename: Andreas
authors.initials: A
authors.lastname: Rivas-Nass
mesh_terms: D000480:Alkynes / Q000737:chemistry*; D002384:Catalysis; D007094:Imides / Q000737:chemistry*; D012428:Ruthenium / Q000737:chemistry*
chemical_list: D000480:Alkynes; D007094:Imides; D012428:Ruthenium