Severe cutaneous hypersensitivity to icodextrin in a continuous ambulatory peritoneal dialysis patient.
Icodextrin, a glucose polymer, is widely used as an alternative to glucose as the osmotic agent in peritoneal dialysis (PD). We describe a case of a continuous ambulatory peritoneal dialysis patient who developed severe cutaneous hypersensitivity after initiation of icodextrin PD solution. Erythematous skin lesions gradually disappeared after discontinuation of icodextrin PD solution. Although the safety and efficacy of icodextrin PD solution is well documented, clinicians should be mindful of the possibility of severe adverse cutaneous reactions to icodextrin PD solution.
Lee
Sang Hun
SH
Department of Internal Medicine, Yongdong Severance Hospital, College of Medicine, Institute of Kidney Disease, Yonsei University, Seoul-Korea.
Park
Hyeong Cheon
HC
Sim
Soung Rok
SR
Chung
Soo Jin
SJ
Kim
Ki Joong
KJ
Park
Woo Il
WI
Hong
Soon Won
SW
Ha
Sung Kyu
SK
D000369:Aged, 80 and over; D015314:Dialysis Solutions / Q000008:administration & dosage / Q000009:adverse effects*; D003875:Drug Eruptions / Q000209:etiology* / Q000473:pathology; D005260:Female; D005936:Glucans / Q000008:administration & dosage / Q000009:adverse effects*; D005947:Glucose / Q000008:administration & dosage / Q000009:adverse effects*; D006801:Humans; D000077607:Icodextrin; D010531:Peritoneal Dialysis, Continuous Ambulatory; D012867:Skin / Q000473:pathology
D015314:Dialysis Solutions; D005936:Glucans; D000077607:Icodextrin; D005947:Glucose