title: [Lung cancer in the elderly: performance status and/or geriatric indices?].
abstract: BACKGROUND
  Demographic aging poses a problem of management in patients over 65 years old with lung cancer (LC). Performance status (PS) is an index of global activity that, in part, determines treatment. Geriatric indices allow a multifactorial assessment of the elderly subject. The aim of our study is to evaluate whether PS correlates with the geriatric indices in elderly patients with lung cancer.
  
  
  METHODS
  In a single centre prospective study the geriatric indices (ADL, IADL, PINI, MMS) and the Charlson score (CS) were measured before treatment.
  
  
  RESULTS
  Forty one patients aged 75.7 +/- 6.6 years were included in the study. PS 3-4 was found in 15% of patients and 44% had stage IV disease. Half of them were ADL dependent and 95% were IADL dependent. A MMS<24 was found in 29% and 17% had a PINI > 20. The CS was 2.7 +/- 2.1. There was a correlation between PS and the geriatric indices but no correlation between PS and CS.
  
  
  CONCLUSIONS
  PS is significantly correlated with the geriatric indices but is independent of CS. PS appears to be a good parameter for the assessment of global activity in the elderly subject with LC.
authors.affiliation: Centre Hospitalier de Versailles, Hôpital André Mignot, Service de Pneumologie, Le Chesnay, France. cdujon@ch-versailles.fr
authors.forename: C
authors.initials: C
authors.lastname: Dujon
authors.forename: R
authors.initials: R
authors.lastname: Azarian
authors.forename: V
authors.initials: V
authors.lastname: Azarian
authors.forename: P
authors.initials: P
authors.lastname: Petitpretz
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000375:Aging; D005260:Female; D005602:France; D015577:Geriatric Assessment / Q000706:statistics & numerical data*; D006305:Health Status Indicators; D006801:Humans; D017567:Karnofsky Performance Status / Q000706:statistics & numerical data; D008175:Lung Neoplasms / Q000401:mortality / Q000473:pathology / Q000628:therapy; D008297:Male; D020360:Neoadjuvant Therapy / Q000379:methods; D009367:Neoplasm Staging; D011237:Predictive Value of Tests; D011446:Prospective Studies; D012720:Severity of Illness Index; D016019:Survival Analysis