Interstitial cystitis in a woman with systemic mastocytosis.
Studies have reported detrusor mastocytosis in patients with interstitial cystitis. The author describes a patient with systemic mastocytosis who was confirmed to have detrusor mastocytosis and interstitial cystitis. She responded to therapy with pentosanpolysulfate. The literature on systemic mastocytosis and the role of mast cells in the pathophysiology of interstitial cystitis are reviewed.
Roth
Ted M
TM
Women's Specialty Center, Central Maine Medical Center, 287 Main St., Lewiston, ME 04240, USA. troth@maine.rr.com
D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use*; D018856:Cystitis, Interstitial / Q000150:complications* / Q000188:drug therapy; D005260:Female; D006801:Humans; D034721:Mastocytosis, Systemic / Q000150:complications* / Q000188:drug therapy; D008875:Middle Aged; D010426:Pentosan Sulfuric Polyester / Q000627:therapeutic use*
D000894:Anti-Inflammatory Agents, Non-Steroidal; D010426:Pentosan Sulfuric Polyester