title: Presence or the emergence of a F317L BCR-ABL mutation may be associated with resistance to dasatinib in Philadelphia chromosome-positive leukemia.
authors.forename: Simona
authors.initials: S
authors.lastname: Soverini
authors.forename: Giovanni
authors.initials: G
authors.lastname: Martinelli
authors.forename: Sabrina
authors.initials: S
authors.lastname: Colarossi
authors.forename: Alessandra
authors.initials: A
authors.lastname: Gnani
authors.forename: Fausto
authors.initials: F
authors.lastname: Castagnetti
authors.forename: Gianantonio
authors.initials: G
authors.lastname: Rosti
authors.forename: Costanza
authors.initials: C
authors.lastname: Bosi
authors.forename: Stefania
authors.initials: S
authors.lastname: Paolini
authors.forename: Michela
authors.initials: M
authors.lastname: Rondoni
authors.forename: Pier Paolo
authors.initials: PP
authors.lastname: Piccaluga
authors.forename: Francesca
authors.initials: F
authors.lastname: Palandri
authors.forename: Panagiota
authors.initials: P
authors.lastname: Giannoulia
authors.forename: Giulia
authors.initials: G
authors.lastname: Marzocchi
authors.forename: Simona
authors.initials: S
authors.lastname: Luatti
authors.forename: Nicoletta
authors.initials: N
authors.lastname: Testoni
authors.forename: Ilaria
authors.initials: I
authors.lastname: Iacobucci
authors.forename: Daniela
authors.initials: D
authors.lastname: Cilloni
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Saglio
authors.forename: Michele
authors.initials: M
authors.lastname: Baccarani
mesh_terms: D000328:Adult; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D001752:Blast Crisis / Q000188:drug therapy / Q000235:genetics; D017322:Clinical Trials, Phase II as Topic; D000069439:Dasatinib; D018450:Disease Progression; D019008:Drug Resistance, Neoplasm; D005260:Female; D016313:Genes, abl; D006801:Humans; D007930:Leucine; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000188:drug therapy* / Q000235:genetics*; D008297:Male; D008875:Middle Aged; D009154:Mutation; D010649:Phenylalanine; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000188:drug therapy / Q000235:genetics; D047428:Protein Kinase Inhibitors / Q000627:therapeutic use; D011743:Pyrimidines / Q000627:therapeutic use*; D013844:Thiazoles / Q000627:therapeutic use*; D017211:Treatment Failure
chemical_list: D000970:Antineoplastic Agents; D047428:Protein Kinase Inhibitors; D011743:Pyrimidines; D013844:Thiazoles; D010649:Phenylalanine; D007930:Leucine; D000069439:Dasatinib