Multiple lung adenocarcinomas and AAH treated by surgical resection.
Atypical adenomatous hyperplasia (AAH) is often found in the lungs of patients with multiple primary lung adenocarcinoma; however, treatment for such patients has not been clearly defined. This report presents a case of multiple primary lung adenocarcinoma with multiple AAH treated by surgery. A 55-year-old man underwent two operations in 3 years and 8 months. Thirteen tumorous lesions were resected; 10 lesions were diagnosed as primary lung adenocarcinoma and the others as AAH. Two years and 6 months after the second operation, radiographic examination showed no evidence of tumor recurrence. The clinical course indicates that surgery can be a treatment strategy for synchronous or metachronous lung carcinoma with AAH.
Seki
Minako
M
Department of Surgery, Hiratsuka City Hospital, Minamihara 1-19-1, Hiratsuka, Kanagawa 254-0065, Japan. zabija@mvg.biglobe.ne.jp
Akasaka
Yoshikiyo
Y
D000230:Adenocarcinoma / Q000473:pathology / Q000601:surgery*; D006801:Humans; D006965:Hyperplasia / Q000473:pathology / Q000601:surgery; D008175:Lung Neoplasms / Q000473:pathology / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D016609:Neoplasms, Second Primary / Q000473:pathology / Q000601:surgery; D014057:Tomography, X-Ray Computed