title: Anaplastic astrocytoma presenting as reversible posterior leukoencephalopathy syndrome.
abstract: We report a 60-year-old man with grade III astrocytoma, who presented with status epilepticus. The initial MRI did not demonstrate typical findings of an astrocytoma but rather showed reversible posterior leukoencephalopathy syndrome (RPLS). N-Isopropil-p-[I] iodoamphetamine single photon emission computed tomography (SPECT) demonstrated hyperperfusion in this area. A brain tumor should be considered and the patient carefully followed by MRI, even if the MRI white matter lesion pattern suggests RPLS. This is especially relevant in the presence of atypical findings for RPLS on SPECT.
authors.affiliation: Research Institute for Neurological Diseases and Geriatrics, Department of Neurology and Gerontology, Kyoto Prefectural University of Medicine, Kyoto, Japan. tomo-kayo@k8.dion.ne.jp
authors.forename: Tomokatsu
authors.initials: T
authors.lastname: Yoshida
authors.forename: Fumitoshi
authors.initials: F
authors.lastname: Niwa
authors.forename: Satoshi
authors.initials: S
authors.lastname: Kimura
authors.forename: Masanori
authors.initials: M
authors.lastname: Nakagawa
mesh_terms: D001254:Astrocytoma / Q000150:complications / Q000175:diagnosis* / Q000000981:diagnostic imaging; D001927:Brain Diseases / Q000150:complications / Q000175:diagnosis* / Q000000981:diagnostic imaging; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D008875:Middle Aged; D009778:Occipital Lobe / Q000000981:diagnostic imaging / Q000473:pathology*; D013226:Status Epilepticus / Q000209:etiology; D015899:Tomography, Emission-Computed, Single-Photon / Q000379:methods