title: Acute renal failure in a patient with paroxysmal cold hemoglobinuria.
abstract: Acute renal failure following auto-immune hemolysis is rare. We report a child with acute paroxysmal cold hemoglobinuria (PCH) complicated by renal failure. She was treated by peritoneal dialysis and red blood cell transfusion. After 2 weeks she had made a complete recovery with a normal blood count and renal profile, and the peritoneal dialysis catheter was removed. Extensive investigation, including an analysis of heme oxygenase-1 gene promoter region polymorphisms, failed to identify a cause for the renal failure in this patient.
authors.affiliation: Regional Paediatric Nephro-Urology Service, Southampton General Hospital, Tremona Road, Southampton, SO16 6YD, UK.
authors.forename: Daljit K
authors.initials: DK
authors.lastname: Hothi
authors.forename: Paul
authors.initials: P
authors.lastname: Bass
authors.forename: Mary
authors.initials: M
authors.lastname: Morgan
authors.forename: Jayshree
authors.initials: J
authors.lastname: Acharya
authors.forename: Steve E
authors.initials: SE
authors.lastname: Humphries
authors.forename: Rodney D
authors.initials: RD
authors.lastname: Gilbert
mesh_terms: D058186:Acute Kidney Injury / Q000209:etiology* / Q000628:therapy; D002675:Child, Preschool; D005260:Female; D006457:Hemoglobinuria, Paroxysmal / Q000150:complications* / Q000175:diagnosis; D006801:Humans