title: CTX-M beta-lactamase-producing Escherichia coli in French hospitals: prevalence, molecular epidemiology, and risk factors.
abstract: In 2004, 65 CTX-M-producing Escherichia coli isolates were collected from infected patients in four French hospitals. The blaCTX-M-15 genes were predominant. Pulsed-field gel electrophoresis highlighted a clonal propagation of CTX-M-15-producing strains belonging to phylogenetic group B2, notably in the community. The main risk factors for acquiring these isolates were urinary tract infections or the presence of a urinary catheter in diabetic or renal failure patients.
authors.affiliation: Laboratoire Universitaire d'Antibiologie, Faculté de Médecine, CS83021, Avenue Kennedy, 30908 Nîmes Cedex 02, France.
authors.forename: Jean-Philippe
authors.initials: JP
authors.lastname: Lavigne
authors.forename: Hélène
authors.initials: H
authors.lastname: Marchandin
authors.forename: Julien
authors.initials: J
authors.lastname: Delmas
authors.forename: Jérôme
authors.initials: J
authors.lastname: Moreau
authors.forename: Nicole
authors.initials: N
authors.lastname: Bouziges
authors.forename: Evelyne
authors.initials: E
authors.lastname: Lecaillon
authors.forename: Laurent
authors.initials: L
authors.lastname: Cavalie
authors.forename: Hélène
authors.initials: H
authors.lastname: Jean-Pierre
authors.forename: Richard
authors.initials: R
authors.lastname: Bonnet
authors.forename: Albert
authors.initials: A
authors.lastname: Sotto
mesh_terms: D000368:Aged; D016521:Electrophoresis, Gel, Pulsed-Field; D004926:Escherichia coli / Q000145:classification / Q000187:drug effects / Q000201:enzymology / Q000235:genetics*; D004927:Escherichia coli Infections / Q000453:epidemiology* / Q000382:microbiology; D005260:Female; D005602:France / Q000453:epidemiology; D006761:Hospitals; D006801:Humans; D008297:Male; D017720:Molecular Epidemiology; D010802:Phylogeny; D015995:Prevalence; D012307:Risk Factors; D014552:Urinary Tract Infections / Q000453:epidemiology / Q000382:microbiology; D001618:beta-Lactamases / Q000096:biosynthesis* / Q000235:genetics
chemical_list: C473109:beta-lactamase CTX-M-15; D001618:beta-Lactamases