title: Long-term and short-term alcohol consumption and levels of C-reactive protein.
abstract: The association between alcohol consumption and CRP was evaluated in a longitudinal study among 72 middle aged adults for whom 572 repeated measurements of CRP were obtained. Short- and long-term alcohol consumption were analyzed using moving windows of average alcohol consumption levels to establish a dose-response relationship. To control for intra-individual dependence of measurements, generalised estimating equations were used. Average alcohol consumption during the last 12 months showed a clear U-shaped relationship with CRP-levels, with lowest levels found for moderate alcohol consumption of less than 16 g/day. For short-term alcohol consumption no association was found.
authors.forename: Elke
authors.initials: E
authors.lastname: Raum
authors.forename: Katja
authors.initials: K
authors.lastname: Gebhardt
authors.forename: Matthias
authors.initials: M
authors.lastname: Buchner
authors.forename: Marcus
authors.initials: M
authors.lastname: Schiltenwolf
authors.forename: Hermann
authors.initials: H
authors.lastname: Brenner
mesh_terms: D000328:Adult; D000428:Alcohol Drinking / Q000097:blood*; D002097:C-Reactive Protein / Q000378:metabolism*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D013995:Time
chemical_list: D002097:C-Reactive Protein