title: Early detection of cancer: ideas for a debate.
abstract: Even if the overall number of cancer is increasing, the mortality has started to decrease in the Western World. The role of early detection in this decrease is a matter of debate. To assess its impact on mortality it is important to distinguish between diagnosis of cancer in symptomatic patients, and early detection in asymptomatic individuals who may self-refer or who may be offered ad hoc or systematic screening. The policies for early detection and screening vary greatly between European countries, despite many similarities in their cancer burden, and this partly reflects the uncertainties surrounding asymptomatic testing for cancer. A Task Force of European expert, held in Azzate (VA), Italy, established to address these issues, acknowledged the need for more research in the field of individual risk assessment since general statistics are more and more perceived as inadequate to design personal early detection plans. The group also recognised that combinations of early detection and screening will enforce the effectiveness of new treatments in curbing mortality curves, although policies will vary with different cancers.
authors.affiliation: European School of Oncology, Cordinator Task Force on Early Detection of Cancer, Via del Bollo, 4, 20123 Milan, Italy. rgennari@fastwebnet.it
authors.forename: R
authors.initials: R
authors.lastname: Gennari
authors.forename: U
authors.initials: U
authors.lastname: Veronesi
authors.forename: C
authors.initials: C
authors.lastname: Andreoli
authors.forename: J
authors.initials: J
authors.lastname: Betka
authors.forename: A
authors.initials: A
authors.lastname: Castelli
authors.forename: G
authors.initials: G
authors.lastname: Gatti
authors.forename: J
authors.initials: J
authors.lastname: Hugosson
authors.forename: J M
authors.initials: JM
authors.lastname: Llovet
authors.forename: J
authors.initials: J
authors.lastname: Melia
authors.forename: J A
authors.initials: JA
authors.lastname: Nakhosteen
authors.forename: U
authors.initials: U
authors.lastname: Pastorino
authors.forename: M
authors.initials: M
authors.lastname: Sideri
authors.forename: C
authors.initials: C
authors.lastname: Stephan
authors.forename: P
authors.initials: P
authors.lastname: Veronesi
authors.forename: S
authors.initials: S
authors.lastname: Zurrida
mesh_terms: D001943:Breast Neoplasms / Q000175:diagnosis*; D006528:Carcinoma, Hepatocellular / Q000175:diagnosis*; D015179:Colorectal Neoplasms / Q000175:diagnosis*; D042241:Early Diagnosis; D005260:Female; D006801:Humans; D008113:Liver Neoplasms / Q000175:diagnosis*; D008297:Male; D008545:Melanoma / Q000175:diagnosis*; D011471:Prostatic Neoplasms / Q000175:diagnosis*