Chromatogram simulation by area reproduction.
A modified Poisson function has been developed for the simulation of chromatographic peaks. The proposed model is shown to have the property of exactly recreating the experimentally determined peak area. Model parameters are obtained directly from the experimental peak, and overlapping peaks are deconvoluted such that the area sum of overlapping peaks is kept unchanged. The method was applied to real, complex chromatograms.
Boe
Bjarne
B
National Institute of Nutrition and Seafood Research, P.O. Box 2029 Nordnes, 5817 Bergen, Norway. bjarne.boe@nifes.no
D000465:Algorithms; D002845:Chromatography / Q000379:methods*; D015233:Models, Statistical; D013057:Spectrum Analysis / Q000379:methods