title: [A role of prenatal diagnostics in birth defects occurrence in the Czech Republic in 2004].
abstract: OBJECTIVE
  An analysis of prenatal diagnostics of birth defects in the Czech Republic in 2004 and a comparison to data from 1996 - 2003.
  
  
  METHODS
  A retrospective analysis of data from a Register of Prenatal Diagnostics of the Czech Republic.
  
  
  METHODS
  Data on birth defects in the Czech Republic from particular departments of medical genetics and prenatal diagnostics from 1996 to 2004 time period was used. An analysis of data on prenatal diagnostics of selected type of birth defects was performed.
  
  
  RESULTS
  During 1996 to 2004 period, a total of 4,126 prenatally diagnosed and terminated cases were reported. In 2004, 597 cases were reported, which presents 61.1 cases per 10 000 live births. (The mean rate from the total period under the study was 49.8 per 10 000 live births.)
  
  
  CONCLUSIONS
  Current data on birth defects in a 9-year period in the Czech Republic are presented. The role of prenatal diagnostics in decrease of some severe types of birth defects is underlined.
authors.affiliation: Oddĕlenfí lékarské genetiky, Fakultní Thomayerova nemocnice, Praha.
authors.forename: V
authors.initials: V
authors.lastname: Gregor
authors.forename: A
authors.initials: A
authors.lastname: Sípek
authors.forename: J
authors.initials: J
authors.lastname: Horácek
authors.forename: D
authors.initials: D
authors.lastname: Masátová
mesh_terms: D000025:Abortion, Eugenic / Q000706:statistics & numerical data; D000013:Congenital Abnormalities / Q000175:diagnosis / Q000453:epidemiology*; D018153:Czech Republic / Q000453:epidemiology; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D011247:Pregnancy; D011296:Prenatal Diagnosis