title: Is sudden cardiac death predictable in LEOPARD syndrome?
abstract: We report the sudden cardiac death of a young male presenting with classic clinical features of LEOPARD syndrome, shown to be due to a mutation in the PTPN11 gene, and severe non obstructive hypertrophic cardiomyopathy. We also discuss briefly the usefulness of prophylactic risk stratification in patients with syndromic and non syndromic hypertrophic cardiomyopathy.
authors.affiliation: Pediatric Cardiology, Monaldi Hospital, Second University of Naples, Naples, Italy. limongelligiuseppe@libero.it
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Limongelli
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Pacileo
authors.forename: Raffaele
authors.initials: R
authors.lastname: Calabrò
mesh_terms: D000328:Adult; D002648:Child; D016757:Death, Sudden, Cardiac / Q000209:etiology*; D017809:Fatal Outcome; D005500:Follow-Up Studies; D006801:Humans; D044542:LEOPARD Syndrome / Q000150:complications*; D008297:Male