[Antifungal and phagocytic immunostimulation treatment of chronic disseminated dermatophytosis].
A 39 years old man with a long-standing disseminated dermatophytosis even with several antifungal treatments is presented. From lesions, Trichophyton rubrum var. typical downy, T. tonsurans and Candida albicans were isolated and showed sensivity to azolic compounds in vitro. The phagocytic activity in vitro compared with normal control was depressed. Treatment with itraconazole and immunomodulation using a bacterial antigen was indicated. During the last two years the patient has been clinical and mycologically healthy, and his phagocytosis activity has become normal. In patients with chronic and relapsing dermatophytosis, the immune response evaluation is recommended, and immunomodulation could be useful as a rational measure in patients with a particular immunodeficiency.
Serrano-Jaén
Liliana
L
Servicio de Dermatología y Micología Mèdica, UMAE Hospital de Especialidades "Dr. Bernardo Sepúlveda", IMSS. México D. F., México. liserja@hotmail.com
Méndez-Tovar
Luis J
LJ
Almeida-Arvizu
Víctor
V
Manzano-Gayosso
Patricia
P
Córdova-Martínez
Erika
E
Bazán-Mora
Elva
E
Hernández-Hernández
Francisca
F
López-Martínez
Rubén
R
D000328:Adult; D000935:Antifungal Agents / Q000627:therapeutic use*; D003881:Dermatomycoses / Q000188:drug therapy* / Q000276:immunology; D006801:Humans; D007167:Immunotherapy / Q000379:methods*; D008297:Male; D016896:Treatment Outcome
D000935:Antifungal Agents