title: Investigation of the functional variant c.-169T > C of the Fc receptor-like 3 (FCRL3) gene in alopecia areata.
abstract: A functional variant in the Fc receptor-like 3 (FCRL3) gene has been implicated in susceptibility to autoimmune diseases such as rheumatoid arthritis, systemic lupus erythematosus and autoimmune thyroid disease. Investigating a large case-control sample of patients with alopecia areata (AA), we found no evidence for the involvement of FCRL3 in susceptibility to AA.
authors.affiliation: Institute of Human Genetics, University of Bonn, Bonn, Germany.
authors.forename: N
authors.initials: N
authors.lastname: Schäfer
authors.forename: B
authors.initials: B
authors.lastname: Blaumeiser
authors.forename: T
authors.initials: T
authors.lastname: Becker
authors.forename: Y
authors.initials: Y
authors.lastname: Freudenberg-Hua
authors.forename: S
authors.initials: S
authors.lastname: Hanneken
authors.forename: S
authors.initials: S
authors.lastname: Eigelshoven
authors.forename: C
authors.initials: C
authors.lastname: Schmael
authors.forename: J
authors.initials: J
authors.lastname: Lambert
authors.forename: J
authors.initials: J
authors.lastname: De Weert
authors.forename: R
authors.initials: R
authors.lastname: Kruse
authors.forename: M M
authors.initials: MM
authors.lastname: Nöthen
authors.forename: R C
authors.initials: RC
authors.lastname: Betz
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000506:Alopecia Areata / Q000235:genetics*; D016022:Case-Control Studies; D002648:Child; D003596:Cytosine; D005260:Female; D020022:Genetic Predisposition to Disease; D014644:Genetic Variation; D006801:Humans; D008297:Male; D008875:Middle Aged; D020641:Polymorphism, Single Nucleotide; D011971:Receptors, Immunologic / Q000235:genetics*; D013941:Thymine
chemical_list: C457775:FCRL3 protein, human; D011971:Receptors, Immunologic; D003596:Cytosine; D013941:Thymine