title: [Ventricular fibrillation during induction of anesthesia in a patient with polycythemia vera].
abstract: A 53-year-old male patient complained of the pain with bilateral hip area and right hip joint and underwent emergency arthroscopy and drainage. Twenty-eight years before, he had suffered from gout and from his abnormal increase of blood cells was diagnosed as polycythemia vera. The laboratory examination at admission showed a marked increase of hemoglobin (17.7 g x dl(-1)) and hematocrit (69.5%). Immediately before induction of anesthesia, 1000 ml of phlebotomy was performed with large fluid infusion. After induction of anesthesia and oro-tracheal intubation, electrocardiogram (ECG) suddenly showed ventricular fibrillation (Vf). Defibrillation was applied and the ECG recovered to sinus rhythm, but 30 min later, ECG showed Vf, again. The increased blood viscosity with polycythemia might have induced coronary ischemia and fatal arrhythmia in the patient. Vigourous hemodilution before surgery should have been performed as prophylactic management of the cardiac episodes in this patient.
authors.affiliation: Department of Anesthesiology and Intensive Care, Hamamatsu University School of Medicine, Hamamatsu 431-3192.
authors.forename: Sakiko
authors.initials: S
authors.lastname: Uchisaki
authors.forename: Genichiro
authors.initials: G
authors.lastname: Matsui
authors.forename: Naoshi
authors.initials: N
authors.lastname: Sato
authors.forename: Yoshiki
authors.initials: Y
authors.lastname: Nakajima
authors.forename: Yushi
authors.initials: Y
authors.lastname: Adachi
authors.forename: Hideki
authors.initials: H
authors.lastname: Sano
authors.forename: Matsuyuki
authors.initials: M
authors.lastname: Doi
authors.forename: Yoshito
authors.initials: Y
authors.lastname: Shiraishi
authors.forename: Shigehito
authors.initials: S
authors.lastname: Sato
mesh_terms: D000768:Anesthesia, General / Q000009:adverse effects*; D004630:Emergencies; D006073:Gout / Q000150:complications; D006801:Humans; D008297:Male; D008875:Middle Aged; D011087:Polycythemia Vera / Q000150:complications*; D014693:Ventricular Fibrillation / Q000209:etiology*