title: Effect of human organism on the oxide layer formed on titanium osteosynthesis plates: a surface analytical study.
abstract: The question of whether or not to remove the titanium osteosynthesis plates used in maxillofacial surgery is not yet answered. These plates can be left a long time in the organism if there is no harmful interaction between the plates and the organism. The authors examined the properties of the surface oxide layers formed on osteosynthesis titanium plates by subsequent thermal and anodic oxidation, together with the properties of plates removed from patients after three years. Surface analytical method Secondary Ion Mass Spectroscopy (SIMS) was chosen. It was found that inside of the about 200-mum thick oxide on the original plates the concentration of impurities is much lower than near the oxide/titanium interface. On the surface of plates removed from the human body, a C (carbon), Ca (calcium) and P (phosphorus) enrichment was detected, suggesting a biological interaction between the organism and the plate. The passivating layer formed with thermal and anodic oxidation has not changed significantly in three years; it resisted to the corrosive effect of the human organism.
authors.affiliation: Semmelweis University, Faculty of Dentistry, Department of Oral and Maxillofacial Surgery and Dentistry, Budapest, Hungary.
authors.forename: Norbert
authors.initials: N
authors.lastname: Velich
authors.forename: Bence
authors.initials: B
authors.lastname: Kádár
authors.forename: Gábor
authors.initials: G
authors.lastname: Kiss
authors.forename: Krisztina
authors.initials: K
authors.lastname: Kovács
authors.forename: Ferenc
authors.initials: F
authors.lastname: Réti
authors.forename: Krisztián
authors.initials: K
authors.lastname: Szigeti
authors.forename: Umberto
authors.initials: U
authors.lastname: Garagiola
authors.forename: György
authors.initials: G
authors.lastname: Szabó
mesh_terms: D001672:Biocompatible Materials / Q000737:chemistry*; D001860:Bone Plates; D006801:Humans; D010084:Oxidation-Reduction; D010087:Oxides / Q000032:analysis*; D013499:Surface Properties; D014025:Titanium / Q000737:chemistry*
chemical_list: D001672:Biocompatible Materials; D010087:Oxides; D014025:Titanium