title: Use of long-acting injectable risperidone before and throughout pregnancy in schizophrenia.
abstract: Data on the use of long-acting injectable (LAI) risperidone, the first atypical depot antipsychotic, during pregnancy are limited. A 35-year-old woman with schizophrenia was given LAI risperidone before and throughout her pregnancy. She gave birth to a female infant weighing 2230 g at 36 weeks and 6 days of pregnancy, following premature rupture of the membranes. The baby had no congenital malformation and was healthy 8 months postnatal. To our knowledge, this is the first reported use of LAI risperidone throughout an entire pregnancy. In this paper, we discuss the rationale and problems of LAI risperidone use in pregnancy, based on a literature review.
authors.affiliation: Department of Psychiatry, Chonnam National University Medical School, 5 Hak-dong, Dong-ku, Kwangju 501-746, Republic of Korea.
authors.forename: Sung-Wan
authors.initials: SW
authors.lastname: Kim
authors.forename: Ki-Min
authors.initials: KM
authors.lastname: Kim
authors.forename: Jae-Min
authors.initials: JM
authors.lastname: Kim
authors.forename: Il-Seon
authors.initials: IS
authors.lastname: Shin
authors.forename: Hee-Young
authors.initials: HY
authors.lastname: Shin
authors.forename: Su-Jin
authors.initials: SJ
authors.lastname: Yang
authors.forename: Jin-Sang
authors.initials: JS
authors.lastname: Yoon
mesh_terms: D000328:Adult; D014150:Antipsychotic Agents / Q000008:administration & dosage*; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D007267:Injections / Q000379:methods; D011247:Pregnancy; D018967:Risperidone / Q000008:administration & dosage*; D012559:Schizophrenia / Q000188:drug therapy*
chemical_list: D014150:Antipsychotic Agents; D018967:Risperidone