Subtype analysis of Cryptosporidium isolates from children in Uganda.
Cryptosporidium hominis and Cryptosporidium parvum isolates from children in Uganda were characterized by DNA sequence analysis of the GP60 gene. Eight alleles were identified, 4 C. hominis and 4 C. parvum, of which 3 represent new C. parvum families. The data show that it is highly likely that the route of transmission is anthroponotic.
Akiyoshi
Donna E
DE
Division of Infectious Diseases, Tufts University Cummings School of Veterinary Medicine, North Grafton, Massachusetts 01536, USA. donna.akiyoshi@tufts.edu
Tumwine
James K
JK
Bakeera-Kitaka
Sabrina
S
Tzipori
Saul
S
D000483:Alleles; D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D002648:Child; D002675:Child, Preschool; D003457:Cryptosporidiosis / Q000453:epidemiology / Q000469:parasitology*; D003458:Cryptosporidium / Q000145:classification* / Q000235:genetics; D016785:Cryptosporidium parvum / Q000145:classification / Q000235:genetics; D016054:DNA, Protozoan / Q000737:chemistry / Q000302:isolation & purification; D003967:Diarrhea / Q000453:epidemiology / Q000469:parasitology; D005243:Feces / Q000469:parasitology; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction; D012150:Polymorphism, Restriction Fragment Length; D015800:Protozoan Proteins / Q000737:chemistry / Q000235:genetics; D016415:Sequence Alignment; D012795:Sialoglycoproteins / Q000737:chemistry / Q000235:genetics; D014454:Uganda / Q000453:epidemiology
D016054:DNA, Protozoan; D015800:Protozoan Proteins; D012795:Sialoglycoproteins; C065610:sialoglycoprotein gp60