title: Enantioselective synthesis of C3 fluoro-MEP.
abstract: The first enantioselective synthesis of C(3) fluoro-MEP is herein reported. The synthetic pathway developed takes advantage of a selective hydrofluorination of a 2,3-epoxy-1-alcohol to introduce the required tertiary fluoride unit.
authors.affiliation: School of Life Sciences, University of Dundee, DD1 5EH, UK.
authors.forename: Stephanos
authors.initials: S
authors.lastname: Ghilagaber
authors.forename: William N
authors.initials: WN
authors.lastname: Hunter
authors.forename: Rodolfo
authors.initials: R
authors.lastname: Marquez
mesh_terms: D000438:Alcohols / Q000737:chemistry; D004896:Erythritol / Q000031:analogs & derivatives* / Q000138:chemical synthesis* / Q000737:chemistry; D005461:Fluorine / Q000737:chemistry; D015394:Molecular Structure; D013237:Stereoisomerism; D013403:Sugar Phosphates / Q000138:chemical synthesis* / Q000737:chemistry*
chemical_list: D000438:Alcohols; D013403:Sugar Phosphates; C517858:phosphoric acid 3-fluoro-2,4-dihdyroxy-3-methylbutyl ester; D005461:Fluorine; C081898:erythritol 4-phosphate; D004896:Erythritol