Utility of screening for other causes of infertility in women with "known" polycystic ovary syndrome.
We investigated the prevalence of abnormal screening results (questionnaire and testing for other causes of oligo-ovulation, male or tubal factor infertility) in a group of 1,313 oligo-ovulatory women (included and excluded subjects) whose condition was screened for inclusion in the Pregnancy in Polycystic Ovary Syndrome trial, a multicenter clinical trial that was conducted at 13 sites in the United States. Other than failure to demonstrate laboratory evidence of hyperandrogenemia, the most common reasons for subject exclusion were persistent oligospermia and tubal factor infertility.
McGovern
Peter G
PG
Department of Obstetrics, Gynecology and Women's Health, UMDNJ-New Jersey Medical School, Newark, New Jersey 07101-1709, USA. mcgovepg@umdnj.edu
Legro
Richard S
RS
Myers
Evan R
ER
Barnhart
Huiman X
HX
Carson
Sandra A
SA
Diamond
Michael P
MP
Carr
Bruce R
BR
Schlaff
William D
WD
Coutifaris
Christos
C
Steinkampf
Michael P
MP
Nestler
John E
JE
Gosman
Gabey
G
Leppert
Phyllis C
PC
Giudice
Linda C
LC
D015984:Causality; D015897:Comorbidity; D005260:Female; D006801:Humans; D007247:Infertility, Female / Q000175:diagnosis* / Q000453:epidemiology*; D008403:Mass Screening / Q000379:methods* / Q000706:statistics & numerical data*; D011085:Polycystic Ovary Syndrome / Q000175:diagnosis* / Q000453:epidemiology*; D015995:Prevalence; D018570:Risk Assessment / Q000379:methods*; D012307:Risk Factors; D014481:United States