title: Recent acquisitions in acquired and congenital von Willebrand disorders.
abstract: von Willebrand factor is a multimeric plasma protein that mediates platelet adhesion as well as platelet aggregation at sites of vascular injury and, moreover, acts as a carrier of factor VIII. Its deficiency is associated with a bleeding tendency. The progresses in the pathophysiology, diagnosis and management of inherited von Willebrand disease and acquired von Willebrand syndrome will be discussed in this review.
authors.affiliation: Servizio di Immunoematologia e Trasfusione, Azienda Ospedaliera Policlinico, Piazzale L. Scuro, and Istituto di Chimica e Microscopia Clinica, Dipartimento di Scienze Biomediche e Morfologiche, Università di Verona, Italy. mfranchini@univr.it
authors.forename: Massimo
authors.initials: M
authors.lastname: Franchini
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Lippi
mesh_terms: D015415:Biomarkers; D006801:Humans; D014842:von Willebrand Diseases / Q000145:classification / Q000378:metabolism* / Q000473:pathology* / Q000628:therapy; D014841:von Willebrand Factor / Q000235:genetics / Q000378:metabolism
chemical_list: D015415:Biomarkers; D014841:von Willebrand Factor