[Influence of Lactobacillus on the migration activity of macrophages].
Influence of Lactobacillus on the migration activity of intact macrophages during their cultivation with serum and supernatant of cells from Peyer's patches and spleen that were obtained from mice of CBA line orally sensibilized with lactobacteria was studied. Data about stimulation of production of factor inhibiting migration of macrophages by immunocompetent cells and development of delayed-hypersensivity reaction are obtained. Mechanisms of complex influence of lactobacteria on cell factors of innate and adaptive immunity are discussed.
Zorina
V V
VV
Nikolaeva
T N
TN
Shapovalova
O V
OV
D000818:Animals; D002478:Cells, Cultured; D017077:Culture Media, Conditioned / Q000378:metabolism; D006968:Hypersensitivity, Delayed; D007106:Immune Sera / Q000276:immunology; D007778:Lactobacillus / Q000276:immunology*; D008124:Locomotion / Q000276:immunology; D008263:Macrophage Migration-Inhibitory Factors / Q000276:immunology* / Q000378:metabolism; D017737:Macrophages, Peritoneal / Q000276:immunology* / Q000382:microbiology; D008297:Male; D051379:Mice; D008808:Mice, Inbred CBA; D010581:Peyer's Patches / Q000276:immunology* / Q000378:metabolism; D013154:Spleen / Q000276:immunology* / Q000378:metabolism
D017077:Culture Media, Conditioned; D007106:Immune Sera; D008263:Macrophage Migration-Inhibitory Factors