title: Clinical observation on juvenile macular hole without trauma and hypermyopia.
abstract: OBJECTIVE
  To investigate the clinical characteristics of juvenile macular hole without trauma and hypermyopia, and research the mechanism of macular hole.
  
  
  METHODS
  Sixty-seven patients less than 40 years of age were studied retrospectively from June 1998 to March 2003. Five cases (7 eyes) aged from 22 to 38 years were reported and the clinical characteristics that had macular hole without trauma or hypermyopia were summed up.
  
  
  RESULTS
  There was 1 male and 4 females with visual acuity from 0.08 to 0.8. The images of optical coherence tomography (OCT) showed full thickness macular hole in 5 patients (7 eyes), and the diameters were from 87 to 1043 microm. Among them, 2 cases were combined with retina pigmentosa; 1 case with binocular Coat's disease; 1 case had bilateral macular hole combined with Eagles' disease; 1 case was combined with 2-2.5PD old retinochoroidal lesion under middle-peripheral fundus, and 1.5 PD retinal pigment epithelium (RPE) defect on the optical disk.
  
  
  CONCLUSIONS
  The juvenile macular hole without trauma and hypermyopia combined the different retina vascular damages and the RPE defects.
authors.affiliation: Shenzhen Ophthalmic Center, Medical College of Jinan University, Shenzhen Eye Hospital, Shenzhen 518001, China.
authors.forename: Tieying
authors.initials: T
authors.lastname: Zhao
authors.forename: Qingshan
authors.initials: Q
authors.lastname: Chen
authors.forename: Ming
authors.initials: M
authors.lastname: Li
authors.forename: Xunqing
authors.initials: X
authors.lastname: Gu
authors.forename: Rulong
authors.initials: R
authors.lastname: Gao
authors.forename: Feng
authors.initials: F
authors.lastname: Wen
mesh_terms: D000328:Adult; D005131:Eye Injuries; D005260:Female; D006801:Humans; D008297:Male; D009216:Myopia; D010857:Pigment Epithelium of Eye / Q000473:pathology*; D012167:Retinal Perforations / Q000150:complications* / Q000175:diagnosis; D012171:Retinal Vessels / Q000473:pathology*; D012174:Retinitis Pigmentosa / Q000150:complications; D012189:Retrospective Studies; D041623:Tomography, Optical Coherence; D014792:Visual Acuity; D055815:Young Adult