title: Relatively small size linitis plastica of the stomach: multislice CT detection of tissue fibrosis.
abstract: BACKGROUND
  Linitis plastica (scirrhous gastric carcinoma) has a poor prognosis due to delay in diagnosis. Pathological feature of this tumor is diffuse fibrosis of the gastric wall. Detection of small fibrotic lesion in the gastric wall would contribute to early diagnosis of linitis plastica, since the primary lesion usually lacks remarkable protrusion or ulceration.
  
  
  METHODS
  We performed a multislice CT evaluation of 20 patients with gastric carcinoma with 8 data acquisition system (Aquilion, Toshiba Medical Systems Corporation, Japan).
  
  
  RESULTS
  Out of 20 primary lesions, 3 were diagnosed as relatively small size (less than 10 cm in maximum diameter) linitis plastica. We have successfully demonstrated an en face virtual endoscopic image of the primary ulcers of linitis plastica by arterial-phase, and reactive fibrosis (a desmoplastic response) of the gastric wall by delayed-phase multiplanar reformation (MPR) images perpendicular to the en face image. This preoperative information was useful to evaluate extent of tumor invasion.
  
  
  CONCLUSIONS
  The multislice CT evaluation of linitis plastica using delayed-phase images was potentially useful in the detection of relatively small fibrotic lesion and in determining the optimal mode of resection of the stomach.
authors.affiliation: Department of Surgery, Fujita Health University School of Medicine, Aichi, Japan. maheday@u01.gate01.com
authors.forename: Hideo
authors.initials: H
authors.lastname: Matsui
authors.forename: Hirofumi
authors.initials: H
authors.lastname: Anno
authors.forename: Ichiro
authors.initials: I
authors.lastname: Uyama
authors.forename: Atsushi
authors.initials: A
authors.lastname: Sugioka
authors.forename: Masahiro
authors.initials: M
authors.lastname: Ochiai
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Katada
authors.forename: Akitake
authors.initials: A
authors.lastname: Hasumi
mesh_terms: D000328:Adult; D003287:Contrast Media; D005260:Female; D005355:Fibrosis; D006801:Humans; D007472:Iohexol; D008039:Linitis Plastica / Q000000981:diagnostic imaging* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D011857:Radiographic Image Interpretation, Computer-Assisted; D013274:Stomach Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D014057:Tomography, X-Ray Computed / Q000379:methods*
chemical_list: D003287:Contrast Media; D007472:Iohexol