Hepatitis C virus: virology and experimental systems.
Over the past several years, significant progress has been made toward the understanding of hepatitis C virus, especially the development of in vitro cell culture models. The scientific community now has the tools to gain a better understanding of the virus, which should translate into better clinical therapeutic modalities. Many new drugs are currently being evaluated, and a few are already undergoing clinica trials. This article focuses on the current advances in hepatitis C virus virology.
Liu
Chen
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Department of Pathology, Immunology, and Laboratory Medicine, University of Florida College of Medicine, 1600 SW Archer Road, Gainesville, FL 32610, USA. liu@pathology.ufl.edu
D000818:Animals; D018929:Cell Culture Techniques; D004195:Disease Models, Animal; D016679:Genome, Viral; D016174:Hepacivirus / Q000502:physiology*; D019698:Hepatitis C, Chronic / Q000821:virology*; D022781:Hepatocytes / Q000821:virology; D006801:Humans; D051379:Mice; D014779:Virus Replication