title: Clinical assessment and core outcome variables are poor predictors of hip arthritis diagnosed by MRI in juvenile idiopathic arthritis.
abstract: OBJECTIVE
  To compare the diagnostic performance of clinical assessment against magnetic resonance imaging (MRI) diagnosed hip arthritis in a juvenile idiopathic arthritis (JIA) population. To determine the clinical and serological predictors of MRI diagnosed hip arthritis.
  
  
  METHODS
  A total of 34 JIA patients with established disease (mean disease duration 6.3 yrs) had their hip MRIs scored for features of active hip arthritis and hip damage. Results were compared with clinical variables (disease subtype, history of hip pain, core outcome variables (COV)) and the clinician's assessment of active hip arthritis.
  
  
  RESULTS
  MRI features of active hip arthritis were found in 45 hips (70%) and hip damage in 36 hips (56%). Clinical assessment had fair agreement with MRI scoring of active arthritis in patients with disease duration <4 yrs (kappa score 0.38, P = 0.045). Clinical assessment had a sensitivity of 25.7% and specificity of 91% for detecting MRI diagnosed arthritis. Of the core outcome variables only erythrocyte sedimentation rate predicted inflammation detected on MRI (r = 0.44, P = 0.014).
  
  
  CONCLUSIONS
  The association between the clinician's assessment, core outcome variables and MRI findings in this study was limited. This indicates that clinical and laboratory findings are inadequate diagnostic tools for the assessment of hip arthritis when compared with MRI as the gold standard.
authors.affiliation: Paediatric Rheumatology Department, Birmingham Children's Hospital, Steelhouse Lane, Birmingham B4 6NH, UK. K.Nistala@ich.ucl.ac.uk
authors.forename: K
authors.initials: K
authors.lastname: Nistala
authors.forename: J
authors.initials: J
authors.lastname: Babar
authors.forename: K
authors.initials: K
authors.lastname: Johnson
authors.forename: P
authors.initials: P
authors.lastname: Campbell-Stokes
authors.forename: K
authors.initials: K
authors.lastname: Foster
authors.forename: C
authors.initials: C
authors.lastname: Ryder
authors.forename: J E
authors.initials: JE
authors.lastname: McDonagh
mesh_terms: D000293:Adolescent; D000328:Adult; D001171:Arthritis, Juvenile / Q000175:diagnosis*; D001799:Blood Sedimentation; D002648:Child; D002675:Child, Preschool; D006621:Hip Joint / Q000473:pathology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D015203:Reproducibility of Results; D012189:Retrospective Studies; D012720:Severity of Illness Index