Nonaqueous capillary electrophoresis in pharmaceutical analysis.
This review presents different solvents and electrolytes commonly used as BGEs in NACE for the analysis of pharmaceutical compounds. Most NACE applications carried out since 1998 for the analysis of compounds of pharmaceutical interest are presented in four tables: (i) analysis of drugs and related substances, (ii) analysis of chiral substances, (iii) analysis of phytochemical extracts and (iv) analysis of drugs in biological fluids. These selected examples are used to illustrate the interest in NACE versus conventional aqueous CE.
Geiser
Laurent
L
Laboratory of Analytical Pharmaceutical Chemistry, School of Pharmaceutical Sciences, University of Geneva, University of Lausanne,Geneva, Switzerland.
Veuthey
Jean-Luc
JL
D002626:Chemistry, Pharmaceutical; D004573:Electrolytes; D019075:Electrophoresis, Capillary / Q000379:methods*; D004364:Pharmaceutical Preparations / Q000032:analysis*; D010936:Plant Extracts / Q000032:analysis; D012997:Solvents
D004573:Electrolytes; D004364:Pharmaceutical Preparations; D010936:Plant Extracts; D012997:Solvents