title: Occurrence of cerebral venous sinus thrombosis in patients with presumed idiopathic intracranial hypertension.
abstract: OBJECTIVE
  To report the rate of occurrence of cerebral venous sinus thrombosis (CVST) in patients with presumed idiopathic intracranial hypertension (IIH).
  
  
  METHODS
  Retrospective chart review.
  
  
  METHODS
  All patients diagnosed with papilledema from November 1, 2002, through October 31, 2003, at 3 tertiary care neuro-ophthalmology centers.
  
  
  METHODS
  Consecutive patients with a diagnosis of papilledema from 3 tertiary care neuro-ophthalmology centers were identified. Patients with space-occupying lesions, hydrocephalus, or meningitis were excluded. The remaining patients were evaluated with lumbar puncture, magnetic resonance imaging (MRI), and magnetic resonance venography (MRV).
  
  
  METHODS
  The rate of occurrence of CVST in patients with presumed IIH.
  
  
  RESULTS
  One hundred thirty-one patients with papilledema were identified. Excluding patients with mass lesions, meningitis, or hydrocephalus, the occurrence of CVST was 10 (9.4%) of 106 patients with presumed IIH. Two additional patients had a diagnosis of suspected CVST. Cerebral venous sinus thrombosis was diagnosed in 1 of the 10 patients with MRI alone, whereas it was evident in all 10 patients with MRV. Underlying risk factors for CVST were identified in 9 of 10 patients.
  
  
  CONCLUSIONS
  Cerebral venous sinus thrombosis accounts for 9.4% of patients with presumed IIH in 3 tertiary care neuro-ophthalmology services. Magnetic resonance venography in combination with MRI is recommended to identify this subgroup of patients.
authors.affiliation: Neuro-ophthalmology Service, Cullen Eye Institute, Baylor College of Medicine, Houston, Texas 77030, USA.
authors.forename: Albert
authors.initials: A
authors.lastname: Lin
authors.forename: Rod
authors.initials: R
authors.lastname: Foroozan
authors.forename: Helen V
authors.initials: HV
authors.lastname: Danesh-Meyer
authors.forename: Gabriella
authors.initials: G
authors.lastname: De Salvo
authors.forename: Peter J
authors.initials: PJ
authors.lastname: Savino
authors.forename: Robert C
authors.initials: RC
authors.lastname: Sergott
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002550:Cerebral Veins; D015170:Cerebrospinal Fluid Pressure; D002648:Child; D005260:Female; D006801:Humans; D020767:Intracranial Thrombosis / Q000209:etiology*; D018810:Magnetic Resonance Angiography; D008297:Male; D010211:Papilledema / Q000150:complications; D010690:Phlebography; D011559:Pseudotumor Cerebri / Q000150:complications*; D012189:Retrospective Studies; D012307:Risk Factors; D012851:Sinus Thrombosis, Intracranial / Q000209:etiology*