title: Sclerosis of postoperative lymphoceles: avoidance of prolonged catheter drainage with use of a fibrin sealant.
abstract: OBJECTIVE
  To review experience with fibrin-based tissue sealant sclerosis of postsurgical lymphoceles at a single institution.
  
  
  METHODS
  Fifteen patients who presented with postsurgical lymphoceles were treated with injection of fibrin tissue sealant. Procedures were performed under fluoroscopic and sonographic guidance. All lymphoceles were drained and sclerosed with a mixture of fibrin sealant and gentamicin. No drainage catheter was left in place. Postprocedural follow-up consisted of imaging and clinical evaluations.
  
  
  RESULTS
  Twelve men and three women (mean age, 52 years) were treated. Eleven patients with lymphoceles were successfully treated with one session of sclerosis. Four patients required more than one treatment (two underwent two sessions, and two underwent three sessions). Seven patients undergoing a single treatment experienced complete resolution, and the remaining patients had smaller, persistent, asymptomatic collections. Imaging mean follow-up was 114 days (range, 5-339 d); mean clinical follow-up was 487 days (range, 195-856 d). There were no periprocedural complications.
  
  
  CONCLUSIONS
  The use of fibrin sealant is safe and effective in the sclerosis of postoperative lymphoceles.
authors.affiliation: Division of Vascular and Interventional Radiology, Dartmouth-Hitchcock Medical Center, One Medical Center Drive, Lebanon, New Hampshire 03756, USA. anne.m.silas@hitchcock.org
authors.forename: Anne M
authors.initials: AM
authors.lastname: Silas
authors.forename: Andrew R
authors.initials: AR
authors.lastname: Forauer
authors.forename: Kiley D
authors.initials: KD
authors.lastname: Perrich
authors.forename: John M
authors.initials: JM
authors.lastname: Gemery
mesh_terms: D000328:Adult; D000368:Aged; D002404:Catheterization / Q000379:methods; D004322:Drainage; D005260:Female; D015718:Fibrin Tissue Adhesive / Q000627:therapeutic use*; D006801:Humans; D016030:Kidney Transplantation / Q000009:adverse effects*; D010535:Laparoscopy; D008210:Lymphocele / Q000150:complications* / Q000000981:diagnostic imaging; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D011468:Prostatectomy / Q000009:adverse effects; D011877:Radionuclide Imaging; D012189:Retrospective Studies; D012598:Sclerosis / Q000209:etiology* / Q000517:prevention & control*; D014463:Ultrasonography
chemical_list: D015718:Fibrin Tissue Adhesive