title: Inositol trisphosphate receptor in higher plants: is it real?
abstract: The receptor for D-myo-inositol 1,4,5-trisphosphate (InsP3-R) has been well documented in animal cells. It constitutes an important component of the intracellular calcium signalling system. Today the corresponding genes in many species have been sequenced and the antibodies against some of the InsP3-Rs are available. In contrast, very little is known about its plant counterpart. Only a few published works have dealt directly with this topic. This review summarizes the available relevant data and determines some properties of putative plant receptor(s) including the in silico search for its gene in plant genomes, in vivo evidence, its electrophysiology, the parameters of InsP3-induced calcium release and InsP3 binding, immunological cross-reactivity, and subcellular localization. Future progress in this area seems to be inevitable as, despite the efforts, its gene in plants has not been identified yet.
authors.affiliation: Department of Biochemistry and Microbiology, Institute of Chemical Technology Prague, Technická 3, 166 28 Prague 6, Czech Republic.
authors.forename: Ondrej
authors.initials: O
authors.lastname: Krinke
authors.forename: Zuzana
authors.initials: Z
authors.lastname: Novotná
authors.forename: Olga
authors.initials: O
authors.lastname: Valentová
authors.forename: Jan
authors.initials: J
authors.lastname: Martinec
mesh_terms: D000818:Animals; D002118:Calcium / Q000378:metabolism; D019295:Computational Biology; D003429:Cross Reactions; D018745:Genome, Plant; D053496:Inositol 1,4,5-Trisphosphate Receptors / Q000737:chemistry / Q000235:genetics* / Q000502:physiology*; D007425:Intracellular Membranes / Q000378:metabolism; D008954:Models, Biological; D010940:Plant Proteins / Q000737:chemistry / Q000235:genetics* / Q000502:physiology*; D015398:Signal Transduction; D014617:Vacuoles / Q000378:metabolism
chemical_list: D053496:Inositol 1,4,5-Trisphosphate Receptors; D010940:Plant Proteins; D002118:Calcium