title: Synthesis of purin-2-yl carboxylate from O6-methylguanosine.
abstract: O6-methylguanosine derivative was treated with sodium nitrite or isoamylnitrite in the presence of the carboxylic acid to give the purin-2-yl carboxylate (2), an unusual product bearing a carboxylic group at 2-position of purine moiety.
authors.affiliation: Faculty of Pharmaceutical Sciences at Kagawa Campus, Tokushima Bunri University, Shido 1314-1, Sanuki City, Kagawa 769-2193, Japan. maruyama@ph.bunri-u.ac.jp
authors.forename: Tokumi
authors.initials: T
authors.lastname: Maruyama
authors.forename: Nobuyasu
authors.initials: N
authors.lastname: Moriwaka
authors.forename: Yosuke
authors.initials: Y
authors.lastname: Demizu
authors.forename: Masami
authors.initials: M
authors.lastname: Ohtsuka
mesh_terms: D006151:Guanosine / Q000031:analogs & derivatives* / Q000737:chemistry; D011684:Purine Nucleosides / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D011684:Purine Nucleosides; D006151:Guanosine; C046175:6'-O-methylguanosine