title: Ventriculo-aortic junction in human root. A geometric approach.
abstract: With advances in tissue engineering and improvement of surgical techniques, stentless biological valves and valve-sparing procedures have become alternatives to traditional aortic valve replacement with stented bioprostheses or mechanical valves. New surgical techniques preserve the advantages of native valves but require better understanding of the anatomical structure of the aortic root. Silicone rubber was injected in fresh aortic roots of nine human cadavers under the physiological closing pressure of 80 mmHg. The casts reproduced every detail of the aortic root anatomy and were used to digitize 27 leaflet attachment lines (LALs) of the aortic valves. LALs were normalized and described with a mathematical model. LALs were found to follow a pattern with the right coronary being the largest followed by the non-coronary and then the left coronary. During diastole, the aortic valve LAL can be described by an intersection between a created tube and an extruded parabolic surface. This geometrical definition of the LAL during end diastole gives a better understanding of the aortic root anatomy and could be useful for heart valve design and improvement of aortic valve reconstruction technique.
authors.affiliation: Physiological Laboratory, School of Mechanical and Aerospace Engineering, Nanyang Technological University, Block N3.1-B2a-01, 50 Nanyang Avenue, Singapore 639798, Singapore. nil_grousson@yahoo.fr
authors.forename: Nil
authors.initials: N
authors.lastname: Grousson
authors.forename: Khee-Hiang
authors.initials: KH
authors.lastname: Lim
authors.forename: Hou-Sen
authors.initials: HS
authors.lastname: Lim
authors.forename: Ean-Tat
authors.initials: ET
authors.lastname: Ooi
authors.forename: Sidney L H
authors.initials: SL
authors.lastname: Salgues
authors.forename: Joon-Hock
authors.initials: JH
authors.lastname: Yeo
authors.forename: Wolfgang A
authors.initials: WA
authors.lastname: Goetz
mesh_terms: D000328:Adult; D001011:Aorta / Q000033:anatomy & histology* / Q000502:physiology*; D001021:Aortic Valve / Q000033:anatomy & histology* / Q000502:physiology*; D001705:Bioprosthesis; D003971:Diastole / Q000502:physiology; D005260:Female; D006350:Heart Valve Prosthesis; D019918:Heart Valve Prosthesis Implantation; D006801:Humans; D008297:Male; D008955:Models, Cardiovascular