title: Clinical resolution of a neonatally eroded giant congenital melanocytic nevus.
abstract: We report an unusual occurrence of spontaneous pigmentary regression with a desmoplastic reaction in a neonatally eroded giant congenital melanocytic nevus. This process has been documented with photographs and skin biopsy specimens. Neonatal histology demonstrated connective tissue proliferation. Histology at age 5 years also demonstrated a very high proportion of amelanotic dermal nevus cells. Regression of pigmentation in our patient may be due to a decrease in melanin production by dermal nevus cells rather than a decrease in their number.
authors.affiliation: Depatment of Dermatology, Cambridge University Hospitals NHS Foundation Trust, Addenbrooke's Hospital, Cambridge, UK. julia.gass@addenbrookes.nhs.uk
authors.forename: Julia K
authors.initials: JK
authors.lastname: Gass
authors.forename: John W
authors.initials: JW
authors.lastname: Grant
authors.forename: Per N
authors.initials: PN
authors.lastname: Hall
authors.forename: David J
authors.initials: DJ
authors.lastname: Atherton
authors.forename: Nigel P
authors.initials: NP
authors.lastname: Burrows
mesh_terms: D002675:Child, Preschool; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D009508:Nevus, Pigmented / Q000175:diagnosis* / Q000473:pathology*; D012075:Remission, Spontaneous