title: Nature vs. nurture: a case report.
abstract: This case report of a young adult male, Mr. A., describes the vulnerability and effects of genetic and environmental factors on the development of psychopathology that can lead to long-term in-patient stays. Mr. A. was born to a mother who had untreated mental and substance use conditions. After a premature birth his brain suffered a significant insult as a result of hypoxia and hypoglycemia, and he remained in a neonatal intensive care unit for three weeks. His early childhood was spent in a chaotic and socioeconomically poor environment with a minimally involved mother and father. During childhood, latency, and adolescence Mr. A. experienced significant interpersonal issues. Mr. A. lived primarily with an aunt. He was unable to maintain employment. He is hospitalized in a public facility, is on multiple medications, and has had unsuccessful attempts to maintain community living. The person to whom he refers to as important in his life is his mother, who remains noninvolved. We present this case to illustrate how genetic and environmental influences interact to impact normal developmental pathways. Has nature or nurture played the strongest role in the life of Mr. A.?
authors.affiliation: Delaware Psychiatric Center in New Castle, Deleware, USA.
authors.forename: Jagwinder S
authors.initials: JS
authors.lastname: Sandhu
authors.forename: Carol L
authors.initials: CL
authors.lastname: Kuprevich
mesh_terms: D000328:Adult; D001714:Bipolar Disorder; D004569:Electroencephalography; D004777:Environment; D005219:Father-Child Relations; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007231:Infant, Newborn; D007297:Inpatients; D007361:Intelligence Tests; D007363:Intensive Care Units, Neonatal; D008297:Male; D001523:Mental Disorders / Q000175:diagnosis / Q000209:etiology* / Q000235:genetics; D009034:Mother-Child Relations; D010554:Personality Disorders / Q000175:diagnosis / Q000209:etiology*; D011247:Pregnancy; D011248:Pregnancy Complications; D047928:Premature Birth; D012307:Risk Factors; D012959:Socioeconomic Factors; D019966:Substance-Related Disorders; D013997:Time Factors