[Molecular characterization of HTLV-1 among patients with tropical spastic paraparesis/HTLV-1 associated myelopathy in Belém, Pará].
The present study evaluated the occurrence of HTLV-1 and its subtypes in blood samples of patients presenting symptoms of tropical spastic paraparesis/HTLV-1 associated myelopathy. The detection of HTLV infection was performed by serological and molecular assays. Five patients were infected by HTLV-1 of the Cosmopolitan subtype, subgroup Transcontinental. The results confirm the occurrence of HTLV-1 infection among patients with clinical diagnosis of tropical spastic paraparesis/HTLV-1 associated myelopathy in Belém, Pará.
Souza
Lucinda A
LA
Laboratório de Virologia, Departamento de Patologia, Centro de Ciências Biológicas, Universidade Federal do Pará, Belém, PA.
Lopes
Ivina G L
IG
Maia
Eduardo Leitão
EL
Azevedo
Vânia N
VN
Machado
Luiz Fernando A
LF
Ishak
Marluísa O G
MO
Ishak
Ricardo
R
Vallinoto
Antonio Carlos R
AC
D001483:Base Sequence; D004279:DNA, Viral / Q000032:analysis; D004797:Enzyme-Linked Immunosorbent Assay; D015368:Human T-lymphotropic virus 1 / Q000235:genetics*; D006801:Humans; D008969:Molecular Sequence Data; D015493:Paraparesis, Tropical Spastic / Q000175:diagnosis / Q000821:virology*; D016133:Polymerase Chain Reaction; D016415:Sequence Alignment
D004279:DNA, Viral