title: The expression of TCR-gamma delta/CD3 complex in neoplastic gamma delta T-cell.
abstract: We describe that the neoplastic gammadelta T-cells from patients with hepatosplenic gammadelta T-cell lymphoma have a lower expression of TCR-gammadelta/CD3 complex compared to their normal or reactive counterparts. Interestingly, with the use of an appropriate antibody association, this feature is easily and rapidly observed on flow cytometry graphics.
authors.forename: Lucile
authors.initials: L
authors.lastname: Baseggio
authors.forename: Françoise
authors.initials: F
authors.lastname: Berger
authors.forename: Guillaume
authors.initials: G
authors.lastname: Monneret
authors.forename: Jean-Pierre
authors.initials: JP
authors.lastname: Magaud
authors.forename: Gilles
authors.initials: G
authors.lastname: Salles
authors.forename: Pascale
authors.initials: P
authors.lastname: Felman
mesh_terms: D017252:CD3 Complex / Q000096:biosynthesis* / Q000097:blood; D015972:Gene Expression Regulation, Neoplastic / Q000276:immunology*; D006801:Humans; D016399:Lymphoma, T-Cell / Q000097:blood* / Q000276:immunology; D016692:Receptors, Antigen, T-Cell, gamma-delta / Q000096:biosynthesis* / Q000097:blood
chemical_list: D017252:CD3 Complex; D016692:Receptors, Antigen, T-Cell, gamma-delta