[The antithrombotic-treated patient].
Management of perioperative treatment with anticoagulants and antiplatelet drugs is a complex medical problem. Careful preoperative evaluation of the risk of bleeding and thromboembolism with and without of antithrombotic therapy is the key prerequisite to secure safe outcome of elective, invasive procedures performed on patients treated with antithrombotic agents. In emergency cases, knowledge of the pharmacokinetics and pharmacodynamics of antithrombotic drugs and of the effect of antidotes and blood-derived, recombinant, and other haemostatic products is important.
Nielsen
Jørn Dalsgaard
JD
Amtssygehuset i Gentofte, Trombosecentret, Klinisk-biokemisk Afdeling, H:S Bispebjerg Hospital, Hellerup. jdn@dadlnet.dk
Rasmussen
Hans Morten Schnack
HM
Husted
Steen Elkjaer
SE
D000925:Anticoagulants / Q000008:administration & dosage / Q000009:adverse effects* / Q000493:pharmacokinetics; D017558:Elective Surgical Procedures / Q000009:adverse effects; D004630:Emergencies; D005343:Fibrinolytic Agents / Q000008:administration & dosage / Q000009:adverse effects* / Q000493:pharmacokinetics; D006470:Hemorrhage / Q000139:chemically induced* / Q000517:prevention & control; D006490:Hemostatics / Q000008:administration & dosage; D006801:Humans; D007431:Intraoperative Complications / Q000139:chemically induced* / Q000517:prevention & control; D010975:Platelet Aggregation Inhibitors / Q000008:administration & dosage / Q000009:adverse effects* / Q000493:pharmacokinetics; D013514:Surgical Procedures, Operative / Q000009:adverse effects*; D013923:Thromboembolism / Q000188:drug therapy / Q000209:etiology
D000925:Anticoagulants; D005343:Fibrinolytic Agents; D006490:Hemostatics; D010975:Platelet Aggregation Inhibitors