title: [High grade transitional cell carcinoma with signet ring cell pattern. Case report].
abstract: OBJECTIVE
  The presence of signet ring cells within a transitional cell carcinoma is a factor of poor prognosis.
  
  
  METHODS
  We report the case of a 69-year-old male patient with the diagnosis of high grade transitional cell carcinoma with signet ring cell pattern, the presence of which could have been foreseen in serial cytological tests performed after the clinical debut.
  
  
  RESULTS
  To achieve such a diagnosis, it is necessary to rule out the possibility of metastasis or infiltration of a neoplasia from other organ.
  
  
  CONCLUSIONS
  Both the presence of an in situ neoplasia or the coexistence of infiltrative transitional cell tumor can help to determine primary origin of these neoplasias.
authors.affiliation: Servicio de Anatomía Patològica, Hospital de Jerez de la Frontera, Cádiz, España. javiertorresgomez@yahoo.es
authors.forename: F J
authors.initials: FJ
authors.lastname: Torres Gómez
authors.forename: A
authors.initials: A
authors.lastname: García Escudero
authors.forename: F J
authors.initials: FJ
authors.lastname: Torres Olivera
mesh_terms: D000368:Aged; D018279:Carcinoma, Signet Ring Cell / Q000473:pathology; D002295:Carcinoma, Transitional Cell / Q000473:pathology*; D006801:Humans; D008297:Male; D001749:Urinary Bladder Neoplasms / Q000473:pathology*