title: Synthesis of 5''-substituted cyclic ADP-carbocyclic-ribose as biological tools.
abstract: 5''-Branched cyclic ADP-carbocyclic-riboses (4 and 5) were designed as biological tools for identifying the target proteins of cyclic ADP-ribose, an intracellular Ca(2+)-mobilizing second messenger. One of the targets, 4, successfully synthesized.
authors.affiliation: Faculty of Pharmaceutical Sciences, Hokkaido University, Kita-12, Nishi-6, Kita-ku, Sapporo 060-0812, Japan.
authors.forename: Natsumi
authors.initials: N
authors.lastname: Sakaguchi
authors.forename: Takashi
authors.initials: T
authors.lastname: Kudoh
authors.forename: Takashi
authors.initials: T
authors.lastname: Murayama
authors.forename: Mitsuhiro
authors.initials: M
authors.lastname: Arisawa
authors.forename: Akira
authors.initials: A
authors.lastname: Matsuda
authors.forename: Satoshi
authors.initials: S
authors.lastname: Shuto
mesh_terms: D000241:Adenosine / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000737:chemistry; D001952:Bridged-Ring Compounds / Q000138:chemical synthesis / Q000737:chemistry; D020013:Calcium Signaling
chemical_list: D001952:Bridged-Ring Compounds; D000241:Adenosine