Methylketone inhibitors of plasmin.
A series of peptide methylketones with generalformula Y-Phe-Lys-CH3 was prepared as potential inhibitors of plasmin.
Markowska
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A
Department of Organic Chemistry, Medical Academy, Bialystok, Poland.
Bruzgo
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I
Midura-Nowaczek
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K
D000577:Amides / Q000737:chemistry; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D005340:Fibrinogen / Q000737:chemistry; D005341:Fibrinolysin / Q000037:antagonists & inhibitors*; D007659:Ketones / Q000138:chemical synthesis* / Q000494:pharmacology*; D009682:Magnetic Resonance Spectroscopy; D013237:Stereoisomerism; D013329:Structure-Activity Relationship
D000577:Amides; D007659:Ketones; D005340:Fibrinogen; D005341:Fibrinolysin