[Influence of light regimens, melatonin, and epitalon on amylase activity in the pancreas and small intestine in rats of different age].
The study shows that keeping rats in different light modes has a different impact on pancreatic and intestine amylase activity and has its peculiarities in regard of age as well as geroprotectors' influence on it. Melatonin use entails pancreatic amylase activity increase in mature animals in natural light of the North-West of Russia (NL) and 24-hour constant light (LD) and on the contrary amylase activity drops in case of using epitalon. Simultaneously, the enzyme activity in young and old rats under LD, melatonin and epitalon decreases. Intestine amylase activity influenced by both preparations rises in NL and drops in LD mode with respect to the control group.
Svechkina
E B
EB
Tiutiunnik
N N
NN
Vinogradova
I A
IA
D000375:Aging / Q000187:drug effects / Q000378:metabolism / Q000528:radiation effects; D000681:Amylases / Q000378:metabolism*; D000818:Animals; D005260:Female; D007421:Intestine, Small / Q000187:drug effects / Q000201:enzymology* / Q000528:radiation effects; D008027:Light; D008297:Male; D008550:Melatonin / Q000494:pharmacology*; D009842:Oligopeptides / Q000494:pharmacology*; D010179:Pancreas / Q000187:drug effects / Q000201:enzymology* / Q000528:radiation effects; D051381:Rats; D011919:Rats, Inbred Strains
D009842:Oligopeptides; D000681:Amylases; D008550:Melatonin; C421253:alanyl-glutamyl-aspartyl-glycine