title: [Trichloroethylene intoxication presenting with temporal seizures].
abstract: BACKGROUND
  Trichloroethylene (TCE) is extensively used as a degreasing agent in the metal industry and as a solvent for organic compounds. Its neurotoxicity (with respect to both the peripheral and central nervous systems) is now widely acknowledged.
  
  
  METHODS
  Here, we report the case of a 32-year-old male drug addict presenting temporal seizures after "huffing" TCE (i.e. voluntary inhalation). The patient also deve loped a "psycho-organic syndrome" which included cognitive dysfunction (with memory disorders in particular) and personality changes. These disorders had not been noticed by the patient's wife prior to the last episode of inhalation. Four months later, the cognitive disorders had stabilized and no further seizures had been observed.
  
  
  CONCLUSIONS
  The patient's overall clinical picture (notably featuring neuropsychological disorders) and electroencephalographic and brain imaging data argue in favor of a selective effect of TCE on the temporal lobe.
authors.affiliation: Service de Neurologie et Pathologie du Mouvement, EA 2683, Hôpital Roger Salengro, CHRU Lille.
authors.forename: E
authors.initials: E
authors.lastname: Mutez
authors.forename: E
authors.initials: E
authors.lastname: Le Rhun
authors.forename: M P
authors.initials: MP
authors.lastname: Perriol
authors.forename: G
authors.initials: G
authors.lastname: Soto Arès
authors.forename: N
authors.initials: N
authors.lastname: Pécheux
authors.forename: A
authors.initials: A
authors.lastname: Destée
authors.forename: L
authors.initials: L
authors.lastname: Defebvre
mesh_terms: D000328:Adult; D004569:Electroencephalography; D006624:Hippocampus / Q000473:pathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D019966:Substance-Related Disorders / Q000473:pathology; D016896:Treatment Outcome; D014241:Trichloroethylene / Q000506:poisoning*
chemical_list: D014241:Trichloroethylene