title: Natural course of fever during influenza virus infection in children.
abstract: During the 2001-2002 epidemic of influenza virus A/H1N1, A/H3N2, and B, the authors obtained detailed profiles of fever from 118 infected children. The only treatment given was acetaminophen for temperatures greater than 39.0 degrees C. Fever was most prominent in A/H3N2 and young children. Secondary fever was observed frequently at 72 to 132 hours in all types. The duration of fever was associated negatively with the age of the child and positively with the maximal temperature. The information will be no longer available in current era of oseltamivir therapy.
authors.affiliation: Suzuki Pediatric Clinic, Ube, Japan. esuzuki@bronze.ocn.ne.jp
authors.forename: Eitaro
authors.initials: E
authors.lastname: Suzuki
authors.forename: Kiyoshi
authors.initials: K
authors.lastname: Ichihara
authors.forename: Andrew M
authors.initials: AM
authors.lastname: Johnson
mesh_terms: D000082:Acetaminophen / Q000627:therapeutic use; D000704:Analysis of Variance; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D002648:Child; D005260:Female; D005334:Fever / Q000188:drug therapy* / Q000209:etiology*; D006801:Humans; D007251:Influenza, Human / Q000150:complications* / Q000821:virology; D008297:Male; D012008:Recurrence; D012044:Regression Analysis; D016896:Treatment Outcome
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D000082:Acetaminophen