title: Association between paclitaxel and necrotic pancreatitis.
abstract: To our knowledge this is the first reported case of paclitaxel associated necrotic pancreatitis requiring a pancreatic necrostomy. This was a near fatal complication associated with paclitaxel with a high resulting morbidity. Although this is a rare association physicians should be wary of the potential to develop severe pancreatitis in patients receiving this therapeautic agent. Monitoring of serum amylase during therapy is therefore warranted.
authors.affiliation: Rheumatology, Beaumont Hospital, Beaumont Road, Dublin 9. mmcm75@yahoo.com
authors.forename: M A
authors.initials: MA
authors.lastname: McMahon
authors.forename: G
authors.initials: G
authors.lastname: Kearns
authors.forename: J
authors.initials: J
authors.lastname: McCaffrey
authors.forename: L
authors.initials: L
authors.lastname: Grogan
mesh_terms: D000328:Adult; D000972:Antineoplastic Agents, Phytogenic / Q000009:adverse effects* / Q000627:therapeutic use; D001943:Breast Neoplasms / Q000188:drug therapy; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D017239:Paclitaxel / Q000009:adverse effects* / Q000627:therapeutic use; D019283:Pancreatitis, Acute Necrotizing / Q000139:chemically induced*
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D017239:Paclitaxel