[Progress of gene therapy for erectile dysfunction].
Gene therapy is currently investigated in animal studies for treating erectile dysfunction (ED), and is affording an conspicuous therapeutic possibility for the treatment of ED, especially in L-arg-NO-cGMP pathway, ion channel, the protection of nerves and endothelia in erectile tissues. However there still exist so many problems for gene therapy to be effectively applied to the clinical treatment of ED. This review aims to examine the experimental efforts in recent years and tries to give a brief introduction to the new approaches in the field of ED researches.
Chen
Yun
Y
Department of Urology, Drum Tower Hospital Affiliated to Nanjing University Medical College, Nanjing, Jiangsu 210008, China.
Dai
Yu-tian
YT
Sun
Ze-yu
ZY
D000818:Animals; D002450:Cell Communication / Q000235:genetics; D007172:Erectile Dysfunction / Q000628:therapy*; D015316:Genetic Therapy; D007473:Ion Channels / Q000235:genetics; D008297:Male; D009414:Nerve Growth Factors / Q000235:genetics; D051381:Rats; D014162:Transfection; D042461:Vascular Endothelial Growth Factor A / Q000235:genetics
D007473:Ion Channels; D009414:Nerve Growth Factors; D042461:Vascular Endothelial Growth Factor A