title: Structural stability and length of I-motif of G-quartet in DNA octaplex.
abstract: To confirm that longer DNA strands with sequences gcGA[G](n)Agc can form an octaplex, X-ray analyses at n>1 have been performed. Several crystals of d(gcGA[G]2Agc) are obtained under different conditions. It has been found that the crystal obtained with cobalt hexamine suggests a hexaplex formation, while the crystal obtained with Mg2+ and Na+ ions suggests an octaplex formation.
authors.affiliation: Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, Midori-ku, Yokohama 226-8501, Japan.
authors.forename: Kenta
authors.initials: K
authors.lastname: Mitomi
authors.forename: Tanashaya
authors.initials: T
authors.lastname: Ciengshin
authors.forename: Jiro
authors.initials: J
authors.lastname: Kondo
authors.forename: Akio
authors.initials: A
authors.lastname: Takénaka
mesh_terms: D001483:Base Sequence; D018360:Crystallography, X-Ray; D004247:DNA / Q000737:chemistry* / Q000235:genetics*; D006860:Hydrogen Bonding; D008958:Models, Molecular; D009690:Nucleic Acid Conformation; D013816:Thermodynamics
chemical_list: D004247:DNA