title: Electrochemical detection of DNA single base mismatch by the use of strand exchange reaction.
abstract: The electrochemical method based on the strand exchange reaction (SER) for the detection of DNA single-base mismatch has been developed. Different electrochemical responses due to the slower SER rates for mismatch containing DNA than fully matched DNA were observed by using the redox-modified partial duplex DNA immobilized on gold electrode as an analytical probe.
authors.affiliation: Department of Materials Science and Chemistry, Graduate School of Engineering, University of Hyogo, 2167 Syosya, Himeji 671-2201, Japan.
authors.forename: Satoshi
authors.initials: S
authors.lastname: Kumamoto
authors.forename: Atsushi
authors.initials: A
authors.lastname: Maruyama
authors.forename: Mitsunobu
authors.initials: M
authors.lastname: Nakamura
authors.forename: Kazushige
authors.initials: K
authors.lastname: Yamana
mesh_terms: D020137:Base Pair Mismatch; D015374:Biosensing Techniques; D004252:DNA Mutational Analysis / Q000379:methods*; D015342:DNA Probes; D004563:Electrochemistry; D004566:Electrodes; D009693:Nucleic Acid Hybridization; D010084:Oxidation-Reduction
chemical_list: D015342:DNA Probes