title: Clinical use of EBT model Gafchromic film in radiotherapy.
abstract: The Gafchromic EBT was recently introduced in film dosimetry for external beam therapy (EBT). The high spatial resolution, weak energy dependence, and near-tissue equivalence of EBT films make them suitable for measurement of dose distributions in radiotherapy, especially intensity-modulated radiation therapy (IMRT). Starting with a sensitometric curve and dose uncertainty relative to the flatbed scanner, the goal of this study was to find an efficient method of correcting for light scattering, and to compare dose distribution supplied by Gafchromic EBT with the distribution obtained with a 2D ion-chamber detector system. Light scattering was analyzed for different levels of dose, and was found to depend on the red-scale value as well as the position of the pixel on the scanner. Many "uniform" films were exposed at different levels of dose to create a two-dimensional matrix correction to take this effect into account. The dose distribution obtained for three clinical beams (10 x 10, 15 x 15 cm open fields and 12 x 12 cm wedge 60 degrees field) were in agreement with those supplied by the 2D array. Gamma index <1 (using 5 mm distance and 5% dose as constraints) for the three fields considered was reached in an average of 98% of the points.
authors.affiliation: Radiation Oncology Department, University of Turin, Turin, Italy. christian.fiandra@unito.it
authors.forename: Christian
authors.initials: C
authors.lastname: Fiandra
authors.forename: Umberto
authors.initials: U
authors.lastname: Ricardi
authors.forename: Riccardo
authors.initials: R
authors.lastname: Ragona
authors.forename: Silvia
authors.initials: S
authors.lastname: Anglesio
authors.forename: Francesca Romana
authors.initials: FR
authors.lastname: Giglioli
authors.forename: Elisa
authors.initials: E
authors.lastname: Calamia
authors.forename: Francesco
authors.initials: F
authors.lastname: Lucio
mesh_terms: D004307:Dose-Response Relationship, Radiation; D004867:Equipment Design; D019544:Equipment Failure Analysis; D005373:Film Dosimetry / Q000295:instrumentation* / Q000379:methods; D011879:Radiotherapy Dosage; D020266:Radiotherapy, Conformal / Q000295:instrumentation* / Q000379:methods; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity