[Na+,K+-ATPase and Ca2+-ATPase isozymes in malignant neoplasms].
A current state of researches on mechanisms of ion homeostasis regulation in the specific conditions of the uncontrolled malignant tumor growth (mainly in carcinomas) concerning the contribution of Na+,K+-ATPase, plasma membrane and sarco(endo)plasmic reticulum Ca2+-ATPases has been reviewed. Particular attention has been focused on the molecular and biochemical links providing the redistribution of the transporting ATPases isozyme pattern for the regulatory requirements of the cell signaling pathways at stable proliferation and viability in malignancy.
Kaplia
A A
AA
Khizhniak
S V
SV
Kudriavtseva
A G
AG
Papageorgakopulu
N
N
Osinskiĭ
D S
DS
D000818:Animals; D017209:Apoptosis; D000252:Calcium-Transporting ATPases / Q000378:metabolism*; D006801:Humans; D007527:Isoenzymes; D009362:Neoplasm Metastasis; D009369:Neoplasms / Q000201:enzymology* / Q000473:pathology; D000254:Sodium-Potassium-Exchanging ATPase / Q000378:metabolism*
D007527:Isoenzymes; D000252:Calcium-Transporting ATPases; D000254:Sodium-Potassium-Exchanging ATPase