[Chemical constituents from roots of Platycodon grandiflorum].
OBJECTIVE
To study the chemical constituents from roots of Platycodon grandiflorum.


METHODS
Column chromatography (silica gel, macroporous resin, sephadex LH - 20 and the preparative RP - HPLC were used to isolate the constituents. Their structures were elucidated by physical and spectral data.


RESULTS
Eight compounds were isolated and identified as tangeritin (1), 3-O-beta-D-glucopyranosylplatycodigenin methyl ester (2), 3-O-beta-D-glucopyranosylplaticogenic acid A lactone (3), 3-O-beta-D-glucopyranosylplatycodigenin (4), deapio-platyconic acid A lactone (5), deapio-platycodin-D (6), platycoside-G1 (7) and platycoside-E (8).


CONCLUSIONS
Compounds 1,3 and 5 were isolated from this plant for the first time.
Li
Ling-Jun
LJ
Department of Chinese Medicine Science and Engineering, Zhejiang University, Hangzhou 310028, China.
Liu
Zhen-Hua
ZH
Chen
Yun
Y
Tian
Jing-Kui
JK
D047309:Flavones / Q000737:chemistry / Q000302:isolation & purification*; D007783:Lactones / Q000737:chemistry / Q000302:isolation & purification*; D009828:Oleanolic Acid / Q000031:analogs & derivatives / Q000737:chemistry / Q000302:isolation & purification; D010936:Plant Extracts / Q000737:chemistry / Q000302:isolation & purification*; D018517:Plant Roots / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D031238:Platycodon / Q000737:chemistry*; D012503:Saponins / Q000737:chemistry / Q000302:isolation & purification
C523493:3-O-beta-D-glucopyranosylplaticogenic acid A lactone; D047309:Flavones; D007783:Lactones; D010936:Plant Extracts; D012503:Saponins; C121315:platycoside E; D009828:Oleanolic Acid; C059006:tangeretin