title: Instantaneous carbon-carbon bond formation using a microchannel reactor with a catalytic membrane.
abstract: Instantaneous catalytic carbon-carbon bond forming reactions were achieved in a microchannel reactor having a polymeric palladium complex membrane. The catalytic membrane was constructed inside the microchannel via self-assembling complexation at the interface between the organic and aqueous phases flowing laminarly, where non-cross-linked polymer-bound phosphine and ammonium tetrachloropalladate dissolved, respectively. A palladium-catalyzed coupling reaction of aryl halides and arylboronic acids was performed using the microchannel reactor to give quantitative yields of biaryls within 4 s of retention time in the defined channel region.
authors.affiliation: Institute for Molecular Science (IMS) and the Graduate University for Advanced Studies, Higashi-yama 5-1, Myodaiji, Okazaki 444-8787, Japan. uo@ims.ac.jp
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Uozumi
authors.forename: Yoichi M A
authors.initials: YM
authors.lastname: Yamada
authors.forename: Tomohiko
authors.initials: T
authors.lastname: Beppu
authors.forename: Naoshi
authors.initials: N
authors.lastname: Fukuyama
authors.forename: Masaharu
authors.initials: M
authors.lastname: Ueno
authors.forename: Takehiko
authors.initials: T
authors.lastname: Kitamori