title: Asymmetric cooperativity in tandem hybridization of the DNA conjugates bearing chiral metal complexes.
abstract: Each of the enantiomers of [Ru(phen)2(dppz)]2+ (phen = 1,10-phenanthroline, dppz = dipyrido[3,2-a:2',3'-c]phenazine) complex was attached to the 5' end of the short oligonucleotide to form a pair of the conjugates. The delta-isomer of them showed a high cooperativity in tandem hybridization to the repetitive sequence, while the lambda-isomer did not.
authors.affiliation: Department of Applied Chemistry and Biochemistry, Faculty of Engineering, Kumamoto University, 2-39-1 Kurokami, Kumamoto 860-8555, Japan.
authors.forename: Toshihiro
authors.initials: T
authors.lastname: Ihara
authors.forename: Yusuke
authors.initials: Y
authors.lastname: Kitamura
authors.forename: Kenji
authors.initials: K
authors.lastname: Okada
authors.forename: Masato
authors.initials: M
authors.lastname: Tazaki
authors.forename: Akinori
authors.initials: A
authors.lastname: Jyo
mesh_terms: D015342:DNA Probes / Q000737:chemistry*; D005456:Fluorescent Dyes / Q000737:chemistry*; D009838:Oligodeoxyribonucleotides / Q000737:chemistry; D009942:Organometallic Compounds / Q000737:chemistry*; D012091:Repetitive Sequences, Nucleic Acid; D013237:Stereoisomerism; D016615:Telomere / Q000737:chemistry
chemical_list: D015342:DNA Probes; D005456:Fluorescent Dyes; D009838:Oligodeoxyribonucleotides; D009942:Organometallic Compounds; C466600:Ru(phen)(2)dipyrido(3,2-a-2',3'-c)phenazine