[Diabetic miocardiopathy].
The world-wide estimated prevalence of diabetes mellitus for 2025 is of about 300 million, resulting from a higher prevalence of obesity and sedentary lifestyles in the developed world. The group of cardiovascular diseases is responsible for 80% of deaths among diabetic patients. Several authors have suggested that patients with diabetes mellitus have a predisposition to develop a form of cardiomyopathy, known as <<diabetic cardiomyopathy>>, which is not related to ischemic heart disease or hypertension, and may progress to cardiac failure. Such condition is known to be associated with a poor prognosis in patients with diabetes mellitus. The prevalence appears to be high. Thus, tissue Doppler techniques added to conventional echocardiography assessment have estimated it to be as high as 75%. However, the use of echocardiography as a screening tool in the asymptomatic diabetic population is problematic. Biomarkers of cardiac dysfunction have been proposed for diagnosis. In this article, we have assessed the role of biomarkers in the diagnosis of this condition and proposed a diagnostic algorithm that may be useful for the assessment of asymptomatic patients with diabetes.
Gil-Ortega
Ignacio
I
Coronary Artery Disease Research Unit. Department of Cardiological Sciences. St. George's Hospital Medical School. Londres. Reino Unido. jkaski@sgul.ac.uk
Carlos Kaski
Juan
J
D009202:Cardiomyopathies / Q000188:drug therapy / Q000209:etiology* / Q000503:physiopathology; D002986:Clinical Trials as Topic; D048909:Diabetes Complications / Q000175:diagnosis* / Q000188:drug therapy / Q000503:physiopathology; D015150:Echocardiography, Doppler; D006801:Humans