title: No association between the Ser9Gly polymorphism of the dopamine D3 receptor gene and schizophrenia in a Spanish sample.
abstract: This study aims to further evaluate the controversial association between the Ser9Gly polymorphism in codon 9 of the D3 dopamine receptor gene (DRD3) and schizophrenia in psychiatric inpatients acutely hospitalized in two general hospitals in Madrid, Spain. The Ser9Gly polymorphism of the DRD3 was examined in 178 schizophrenic patients, 286 patients with other psychiatric diagnoses, and 132 controls recruited. Genotype frequencies were in Hardy-Weinberg equilibrium. No association was found between schizophrenia and the Ser9Gly polymorphism of the D3 dopamine receptor gene.
authors.affiliation: Autonoma University of Madrid, Madrid, Spain.
authors.forename: C Vaquero
authors.initials: CV
authors.lastname: Lorenzo
authors.forename: E
authors.initials: E
authors.lastname: Baca-Garcia
authors.forename: M Diaz
authors.initials: MD
authors.lastname: Hernandez
authors.forename: C Botillo
authors.initials: CB
authors.lastname: Martin
authors.forename: M M
authors.initials: MM
authors.lastname: Perez-Rodriguez
authors.forename: M D
authors.initials: MD
authors.lastname: Saiz-Gonzalez
authors.forename: P
authors.initials: P
authors.lastname: Fernández
authors.forename: F J Quintero
authors.initials: FJ
authors.lastname: Gutierrez
authors.forename: J
authors.initials: J
authors.lastname: Saiz-Ruiz
authors.forename: J Fernandez
authors.initials: JF
authors.lastname: Piqueras
authors.forename: J L Gonzalez
authors.initials: JL
authors.lastname: de Rivera
authors.forename: J
authors.initials: J
authors.lastname: de Leon
mesh_terms: D016022:Case-Control Studies; D005787:Gene Frequency; D008040:Genetic Linkage; D005838:Genotype; D005998:Glycine / Q000235:genetics; D006801:Humans; D020641:Polymorphism, Single Nucleotide; D050637:Receptors, Dopamine D3 / Q000235:genetics*; D012559:Schizophrenia / Q000235:genetics*; D012694:Serine / Q000235:genetics; D013030:Spain
chemical_list: D050637:Receptors, Dopamine D3; D012694:Serine; D005998:Glycine