title: [Genetic control of hydrogen metabolism in cyanobacteria].
abstract: The development of methods for the use of phototrophic cyanobacteria as producers of molecular hydrogen via bioconversion of solar energy is a promising filed of hydrogen energetics. Artificial optimization of hydrogen formation and release is based on studying the genetic control of hydrogen metabolism and the use of genetic approaches for obtaining efficient producer strains. Data on genes coding for the hydrogenases that are responsible for hydrogen uptake and production in cyanobacteria are summarized. Bioinformatic methods have been used to construct the scheme of the hydrogen metabolism gene network of nitrogen-fixing heterocyst cyanobacteria. The possible approaches to constructing the cyanobacterium strains producing molecular hydrogen that would be promising for photobiotechnology by mutagenesis and genetic engineering methods are discussed in terms of this model and analysis of the data on hydrogen-producing mutants.
authors.forename: S V
authors.initials: SV
authors.lastname: Shestakov
authors.forename: L E
authors.initials: LE
authors.lastname: Mikheeva
mesh_terms: D001426:Bacterial Proteins / Q000235:genetics*; D000458:Cyanobacteria / Q000201:enzymology* / Q000235:genetics*; D015971:Gene Expression Regulation, Enzymologic; D005818:Genetic Engineering / Q000379:methods; D006859:Hydrogen / Q000378:metabolism*; D006864:Hydrogenase / Q000235:genetics*; D007218:Industrial Microbiology / Q000379:methods; D009154:Mutation; D009586:Nitrogen Fixation / Q000235:genetics
chemical_list: D001426:Bacterial Proteins; D006859:Hydrogen; D006864:Hydrogenase