title: Severe protracted fever following pneumococcal vaccine.
abstract: Streptococcus pneumoniae is one of the most common virulent pathogens in the world, causing the vast majority of cases of community-acquired pneumonia in patients who are hospitalized as well as a host of other illnesses, ranging in severity from otitis media to septic shock. Primary prevention with pneumococcal vaccines has effectively reduced the rates of associated morbidity and mortality. These various vaccine formulations have all shown excellent safety profiles. Since 1977, when commercial pneumococcal vaccine first became available, fewer than 10 case reports have been published describing the development of serious side effects in adults after their first vaccination. We describe a 40-year-old healthy man who, after receiving polyvalent pneumococcal polysaccharide vaccine, developed severe protracted fever for 9 days.
authors.affiliation: Department of Internal Medicine, Bellevue Hospital Center, New York, New York 10016, USA. leea04@popmail.med.nyu.edu
authors.forename: Arnold
authors.initials: A
authors.lastname: Lee
authors.forename: Rishi
authors.initials: R
authors.lastname: Goyal
authors.forename: Hui Yi
authors.initials: HY
authors.lastname: Shan
mesh_terms: D000328:Adult; D005334:Fever / Q000209:etiology*; D006801:Humans; D008297:Male; D022242:Pneumococcal Vaccines / Q000009:adverse effects*; D013997:Time Factors
chemical_list: D022242:Pneumococcal Vaccines