title: Latex allergy and sensitization in cities: a survey in a population at risk.
abstract: The constant increase in allergic diseases in western countries is correlated with changes in lifestyle and with the deterioration of the air inhaled by the inhabitants because of the growing concentrations of pollutant substances present. Within a population at risk, i.e., the inhabitants of cities, a group of subjects at even higher risk was selected, whose job exposes them to automobile exhaust fumes for many hours a day. All the study subjects underwent allergological screening and spirometry. The results obtained show an overall increase of respiratory allergic diseases but no increased sensitisation to latex. It therefore seems plausible that, besides social and lifestyle changes, the deterioration of the quality of the air could be considered responsible, at least in part, for the growing numbers of allergic subjects. This study offers an opportunity to reconsider the validity of the hygiene hypothesis as an explanation for the increase of allergic disease in western countries, although recent reports have indicated that a sedentary lifestyle may also contribute, together with environmental degradation, to the notably increased prevalence of allergic diseases in large cities in industrialized nations.
authors.affiliation: Department of Internal Medicine, Immunology and Infectious Diseases (MIDIM), University of Bari Medical School, Policlinico, Bari, Italy. mt.ventura@allergy.uniba.it
authors.forename: M T
authors.initials: MT
authors.lastname: Ventura
authors.forename: M
authors.initials: M
authors.lastname: Musi
authors.forename: G
authors.initials: G
authors.lastname: Giuliano
authors.forename: A
authors.initials: A
authors.lastname: Arsieni
authors.forename: E
authors.initials: E
authors.lastname: Di Leo
authors.forename: R
authors.initials: R
authors.lastname: Buquicchio
authors.forename: G
authors.initials: G
authors.lastname: Accettura
authors.forename: A
authors.initials: A
authors.lastname: Spanevello
authors.forename: M P
authors.initials: MP
authors.lastname: Foschino-Barbaro
authors.forename: O
authors.initials: O
authors.lastname: Resta
mesh_terms: D000328:Adult; D000485:Allergens; D003625:Data Collection; D005260:Female; D006801:Humans; D020315:Latex Hypersensitivity / Q000453:epidemiology*; D008019:Life Style; D008297:Male; D008875:Middle Aged; D011159:Population Surveillance; D013147:Spirometry
chemical_list: D000485:Allergens