On-line continuous hemodiafiltration in sepsis.
On-line products of substitution fluid by bicarbonate buffered dialysate permits virtually unlimited fluid volume exchange during continuous hemodiafiltration (CHDF) to critical care. In on-line hemodiafiltration (HDF), endotoxin free dialysate obtained using pyrogen cut filters is infused into the blood circuit, and HDF is automatically performed using the close-loop balancing system of the dialysis machine. On-line CHDF is the application of this on-line HDF to continuous renal replacement therapy in the critical care field. We performed on-line CHDF of the totally in 123 septic shock patients during a 5-year period and the mean survival rate was 54%. We concluded that on-line CHDF system is safe and effective at maintaining acute kidney injury with sepsis.
Kawanishi
Hideki
H
Akane Foundation, Tsuchiya General Hospital 3-30, Nakajima-cho, Naka-ku, Hiroshima 730-8655, Japan.
D003422:Critical Care / Q000379:methods; D015314:Dialysis Solutions / Q000592:standards; D017583:Hemodiafiltration / Q000295:instrumentation / Q000379:methods*; D006801:Humans; D018805:Sepsis / Q000097:blood / Q000628:therapy*; D016896:Treatment Outcome
D015314:Dialysis Solutions