[Gastroesophageal reflux disease pathogenesis].
Pathophysiological mechanisms of gastroesophageal reflux disease are described, including vagal stimulation of motor activity of upper stomach and oaesophagal divisions. Serotonin role is indicated (own research results including), as its place at this mechanisms of NO, cholecistokinin, prostaglandins, epidermal growth factor and other biologically active substances. There are highlighted some aspects of interleukins, adgesive molecules and other components of immune system activity in state of gastroesophageal reflux disease.
Lazebnik
L B
LB
Lychkova
A E
AE
D000818:Animals; D002766:Cholecystokinin / Q000378:metabolism; D004815:Epidermal Growth Factor / Q000378:metabolism; D005764:Gastroesophageal Reflux / Q000276:immunology / Q000503:physiopathology*; D005769:Gastrointestinal Motility / Q000502:physiology; D006801:Humans; D018799:Intercellular Adhesion Molecule-1 / Q000096:biosynthesis; D007378:Interleukins / Q000096:biosynthesis; D009569:Nitric Oxide / Q000378:metabolism; D011453:Prostaglandins / Q000378:metabolism; D012701:Serotonin / Q000378:metabolism; D014630:Vagus Nerve / Q000502:physiology
D007378:Interleukins; D011453:Prostaglandins; D018799:Intercellular Adhesion Molecule-1; D009569:Nitric Oxide; D012701:Serotonin; D004815:Epidermal Growth Factor; D002766:Cholecystokinin