The investigation of Staphylococcus aureus and coagulase-negative staphylococci nasal carriage among patients undergoing haemodialysis.
The frequency of nasal staphylococcal colonization among haemodialysed patients was investigated. The swabs were collected in 1998 and 2004 from 28 and 43 patients, respectively. Staphylococcus aureus colonization rates were 57.1% and 27.9% in 1998 and 2004, respectively. Twenty-six coagulase-negative staphylococci (CNS) isolates were cultured: S. epidermidis (21), S. lugdunensis (2), single S. haemolyticus, S. warneri, and S. capitits isolates. One S. aureus and 10 CNS isolates were methicillin resistant. The methicillin-resistant S. aureus (MRSA) was resistant to beta-lactams, tetracycline, and harbored the pvl gene encoding the Panton-Valentine leukocidin. The decrease in S. aureus colonization at 6-year interval was observed. The presence of the pvl gene and a favorable antibiotic susceptibility pattern of the MRSA suggest that the isolate was a member of community-acquired MRSA (CA-MRSA). Concluding, screening of haemodialysed patients for staphylococcal colonization accompanied by characterization of cultured isolates is important to understand its epidemiology and to develop infection prevention measures and treatment strategies.
Kozioł-Montewka
Maria
M
Department of Clinical Microbiology, Medical University of Lublin, Chodzki 1 Street, 20-093, Lublin, Poland. agola7@wp.pl
Szczepanik
Agnieszka
A
Baranowicz
Iwona
I
Jóźwiak
Lucyna
L
Ksiazek
Andrzej
A
Kaczor
Danuta
D
D002353:Carrier State / Q000453:epidemiology / Q000382:microbiology*; D003030:Coagulase / Q000378:metabolism*; D017714:Community-Acquired Infections / Q000188:drug therapy / Q000453:epidemiology; D004269:DNA, Bacterial / Q000032:analysis / Q000235:genetics; D006801:Humans; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D009666:Nose / Q000382:microbiology*; D006435:Renal Dialysis / Q000009:adverse effects; D013203:Staphylococcal Infections / Q000453:epidemiology* / Q000382:microbiology; D013211:Staphylococcus aureus / Q000187:drug effects / Q000201:enzymology / Q000235:genetics / Q000302:isolation & purification*
D003030:Coagulase; D004269:DNA, Bacterial