title: Thrombotic thrombocytopenic purpura complicating Sjögren's syndrome with crescentic glomerulonephritis and membranous nephritis.
abstract: The association of either thrombotic thrombocytopenic purpura (TTP) or crescentic glomerulonephritis with Sjögren's syndrome is rare. We report a case of TTP appearing after the diagnosis of SjOgren's syndrome with crescentic glomerulonephritis and membranous nephropathy. Circulating immune complex was detected, and immune complex deposits were shown along the capillary walls of renal biopsy specimens. Despite steroid pulse therapy and plasma exchange therapy, the patient died. The etiology of TTP is unclear. This case is important when considering the etiology of TTP related to autoimmune disease.
authors.affiliation: Third Department of Internal Medicine, Tokyo Medical University, 6-7-1 Nishishinjuku, Shinjuku-ku, Tokyo 160-0023, Japan. haruoa@aqua.plala.or.jp
authors.forename: Haruo
authors.initials: H
authors.lastname: Abe
authors.forename: Norioki
authors.initials: N
authors.lastname: Tsuboi
authors.forename: Sonosuke
authors.initials: S
authors.lastname: Yukawa
authors.forename: Souichirou
authors.initials: S
authors.lastname: Tsuji
authors.forename: Haeru
authors.initials: H
authors.lastname: Hayashi
authors.forename: Naoichiro
authors.initials: N
authors.lastname: Yukawa
authors.forename: Hirofumi
authors.initials: H
authors.lastname: Takanashi
authors.forename: Koichiro
authors.initials: K
authors.lastname: Tahara
authors.forename: Norihiko
authors.initials: N
authors.lastname: Tonozuka
authors.forename: Tohru
authors.initials: T
authors.lastname: Hayashi