title: Relationship between serum resistin concentrations and inflammatory markers in patients with type 2 diabetes mellitus.
abstract: To examine whether serum resistin concentrations are associated with metabolic or inflammatory markers in patients with type 2 diabetes mellitus, we examined serum concentrations levels and metabolic or inflammatory markers in 56 patients with type 2 diabetes mellitus and 41 healthy subjects. Serum levels of resistin, serum amyloid A, and soluble vascular cell adhesion molecule-1 were measured by enzyme-linked immunosorbent assay. Serum resistin levels were significantly elevated in diabetic patients compared with those in healthy subjects. Serum resistin concentrations did not correlate with body mass index; however, there was a significant positive correlation between resistin and soluble vascular cell adhesion molecule-1 in diabetic patients. Based on the present results, we conclude that resistin appears to be associated with vascular inflammatory markers in patients with type 2 diabetes mellitus.
authors.affiliation: Department of Endocrinology and Metabolism, NHO Nagasaki Medical Center, Omura 856-8652, Japan.
authors.forename: Huang
authors.initials: H
authors.lastname: Hui-Bing
authors.forename: Kiyoshi
authors.initials: K
authors.lastname: Migita
authors.forename: Taichiro
authors.initials: T
authors.lastname: Miyashita
authors.forename: Yumi
authors.initials: Y
authors.lastname: Maeda
authors.forename: Minoru
authors.initials: M
authors.lastname: Nakamura
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Yatsuhashi
authors.forename: Hiromi
authors.initials: H
authors.lastname: Ishibashi
authors.forename: Katsumi
authors.initials: K
authors.lastname: Eguchi
authors.forename: Hironori
authors.initials: H
authors.lastname: Kimura
mesh_terms: D000328:Adult; D000368:Aged; D015415:Biomarkers; D003924:Diabetes Mellitus, Type 2 / Q000097:blood*; D005260:Female; D006801:Humans; D015850:Interleukin-6 / Q000097:blood*; D008297:Male; D008875:Middle Aged; D052243:Resistin / Q000097:blood*; D000685:Serum Amyloid A Protein / Q000032:analysis*; D019010:Vascular Cell Adhesion Molecule-1 / Q000097:blood*
chemical_list: D015415:Biomarkers; D015850:Interleukin-6; C499624:RETN protein, human; D052243:Resistin; D000685:Serum Amyloid A Protein; D019010:Vascular Cell Adhesion Molecule-1