title: Pituitary carcinoma.
abstract: The presence of distant metastases may be asymptomatic in patients who present with symptoms and signs due to the local mass effects of an invasive pituitary adenoma. A case of pituitary carcinoma in a 54-year-old man who presented with widespread asymptomatic distant metastases 12 years after initial diagnosis is reviewed. The long course and asymptomatic metastases suggested a relatively slow-growing malignancy. The factors that played a role in the pathogenesis of the metastasis are unknown. A review of the literature on pituitary carcinoma suggests that accurate diagnosis and a multidisciplinary approach to management of such lesions emphasizing surgery, radiotherapy, and hormonal manipulation may provide these patients with the longest and best quality of survival.
authors.forename: M D
authors.initials: MD
authors.lastname: Cusimano
authors.forename: P
authors.initials: P
authors.lastname: Ohori
authors.forename: A J
authors.initials: AJ
authors.lastname: Martinez
authors.forename: C
authors.initials: C
authors.lastname: Jungreis
authors.forename: D C
authors.initials: DC
authors.lastname: Wright