[Use of Venofer in management of anemia in cancer patients].
Therapy of anemia raises hemoglobin (Hb) level which in turn improves quality of life. Venofer was tested in 20 anemic (grade 1) patients with various malignancies. The drug was administered in 3 courses, i/v, 200 mg at a 4-5 week interval during chemotherapy. Hb levels rose or remained unchanged in 75%; they fell mostly in cases of tumor progression. There was no correlation between Hb concentration and chemotherapy regimen--with or without platinum. Venofer treatment was followed by improvement in quality of life or by stabilization only in 73.3%. Quality of life improved by 9,3% (FACT-An) after an 1g/dl increase in Hb level. Venofer treatment prevented further anemia.
Makhnova
E V
EV
Livshits
M E
ME
Gershanovich
M L
ML
D000328:Adult; D000368:Aged; D000740:Anemia / Q000097:blood / Q000188:drug therapy* / Q000209:etiology*; D018450:Disease Progression; D004334:Drug Administration Schedule; D005260:Female; D005290:Ferric Compounds / Q000008:administration & dosage / Q000627:therapeutic use*; D000077605:Ferric Oxide, Saccharated; D005937:Glucaric Acid; D006454:Hemoglobins / Q000187:drug effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000097:blood / Q000150:complications* / Q000628:therapy; D011788:Quality of Life; D013395:Sucrose / Q000008:administration & dosage / Q000627:therapeutic use*; D013997:Time Factors; D016896:Treatment Outcome
D005290:Ferric Compounds; D006454:Hemoglobins; D013395:Sucrose; D000077605:Ferric Oxide, Saccharated; D005937:Glucaric Acid