Panniculitis in a patient with mixed connective tissue disease.
A 51-year-old woman who had been suffering from mixed connective tissue disease (MCTD) for 8 years developed an erythematous rash with pain and tenderness on her left leg. A skin biopsy revealed septal panniculitis with multiple lymphangiectasis. No vasculitis was observed. An increase in her prednisolone dose from 5 mg to 20 mg/day led to an improvement in these lesions. Panniculitis is very rare in MCTD. The clinical significance of panniculitis in MCTD is also discussed.
Nakashima
Masahiro
M
Department of Internal Medicine I, National Defense Medical College, 3-2 Namiki, Tokorozawa 359-8513, Japan. kogen@me.ndmc.ac.jp
Suzuki
Kimihiro
K
Okada
Makoto
M
Kataharada
Koji
K
Takada
Kunio
K
Nakanishi
Takashi
T
Kobayashi
Masami
M
Ohsuzu
Fumitaka
F