Can men provide accurate confounder data about their partners for Time-to-Pregnancy studies?
OBJECTIVE
In studies of time to pregnancy (TTP), women's health-related behaviors may confound other determinants of TTP. In many occupation-based TTP studies, all information is collected through the male partner. There are no data on the validity of the man's report of his partner's fertility-related behavior.


METHODS
We studied 202 men and their partners from the most recent pregnancy. Validity of men's reporting on their partner's use of oral contraceptives (OCs) as the last birth control method and her smoking around the beginning of TTP and agreement of coital frequency were assessed.


RESULTS
The index pregnancy was an average of 6 years before interview. Overall percentage of agreement was 81% for OCs as the last contraceptive method (kappa agreement = 0.44). Ninety-five percent of men accurately reported whether their partner smoked (kappa agreement = 0.83). Among couples agreeing on smoking status, 90% agreed on the categorical cigarette number (weighted kappa = 0.60). Reporting accuracy was not influenced by men's characteristics. Median coital frequency was eight times per month, with a weighted kappa = 0.34 after categorization.


CONCLUSIONS
Our data generally justify the use of men's reports of potential confounders in TTP studies when women's reports are not available.
Nguyen
Ruby H N
RH
National Institute of Environmental Health Sciences, Research Triangle Park, NC 27703, USA. nguyen5@niehs.nih.gov
Wilcox
Allen J
AJ
Baird
Donna D
DD
D000328:Adult; D003075:Coitus; D015986:Confounding Factors, Epidemiologic; D003276:Contraceptives, Oral / Q000627:therapeutic use; D004363:Drug Utilization; D005260:Female; D005298:Fertility / Q000502:physiology*; D006801:Humans; D008297:Male; D015203:Reproducibility of Results; D012107:Research Design; D012747:Sexual Partners; D012907:Smoking
D003276:Contraceptives, Oral