title: Room-specific characteristics of suburban homes as predictors of indoor allergen concentrations.
abstract: BACKGROUND
  Room characteristics predicting indoor allergen exposure in suburban homes have not been clearly identified.
  
  
  OBJECTIVE
  To examine relationships between room characteristics and concentrations of indoor allergens in homes of suburban asthmatic patients.
  
  
  METHODS
  The homes of 339 asthmatic children ages 6 to 17 years were studied. Home inspections were conducted by a trained technician, and dust samples were analyzed for indoor allergen content. A high allergen concentration was defined as 8 microg (U)/g or more of fine dust.
  
  
  RESULTS
  Infrequent sheet washing and wall-to-wall carpet were risk factors for high bedroom dust mite concentrations. Infrequent sheet washing was also a risk factor for high Fel d 1 concentrations. Food remains in the bedroom was a risk factor for high bedroom Bla g 1 levels, and exposed food, leaks, and dirty pots were all risk factors for high kitchen Bla g 1 levels. The combination of lack of mattress or pillow encasements, infrequent sheet washing, and carpeting was associated with a 24-fold increase in odds of a high dust mite concentration (odds ratio [OR], 24.1; 95% confidence interval [CI], 3.2-181.4). Among non-cat owners, the combination of stuffed toys on the bed, lack of mattress or pillow encasements, and infrequent sheet washing was associated with a 49-fold increase in odds of a high Fel d 1 level (OR, 49.4; 95% CI, 2.8-887.3). The combination of leaks, exposed food, and dirty pots was associated with a high kitchen Bla g 1 concentration (OR, 10.6; 95% CI, 2.8-40.5).
  
  
  CONCLUSIONS
  Specific room characteristics predict high indoor allergen exposure among children with asthma, and a combination of these characteristics may further increase the risk of high allergen exposure.
authors.affiliation: Department of Pediatrics, Division of Allergy and Immunology, University of Arkansas for Medical Sciences College of Medicine, Arkansas Children's Hospital Research Institute, Little Rock, Arkansas 72202, USA. perrytamarat@uams.edu
authors.forename: Tamara T
authors.initials: TT
authors.lastname: Perry
authors.forename: Robert A
authors.initials: RA
authors.lastname: Wood
authors.forename: Elizabeth C
authors.initials: EC
authors.lastname: Matsui
authors.forename: Jean
authors.initials: J
authors.lastname: Curtin-Brosnan
authors.forename: Cynthia
authors.initials: C
authors.lastname: Rand
authors.forename: Peyton A
authors.initials: PA
authors.lastname: Eggleston
mesh_terms: D000293:Adolescent; D016902:Air Pollution, Indoor / Q000032:analysis*; D000485:Allergens / Q000032:analysis*; D000818:Animals; D000829:Animals, Domestic; D039741:Antigens, Dermatophagoides / Q000032:analysis; D052179:Antigens, Plant; D001249:Asthma / Q000453:epidemiology* / Q000209:etiology; D002415:Cats; D002648:Child; D004285:Dogs; D004391:Dust / Q000032:analysis; D004781:Environmental Exposure / Q000009:adverse effects / Q000032:analysis; D005260:Female; D006023:Glycoproteins / Q000032:analysis; D006798:Housing; D006801:Humans; D008297:Male; D008396:Maryland / Q000453:epidemiology; D016017:Odds Ratio; D012307:Risk Factors; D012882:Skin Tests; D013383:Suburban Population; D011795:Surveys and Questionnaires
chemical_list: D000485:Allergens; D039741:Antigens, Dermatophagoides; D052179:Antigens, Plant; D004391:Dust; D006023:Glycoproteins; C105482:allergen Bla g 1; C091462:allergen Can f I; C059296:Fel d 1 protein, Felis domesticus