title: Liver toxicity after treatment with gefitinib and anastrozole: drug-drug interactions through cytochrome p450?
authors.forename: Paolo
authors.initials: P
authors.lastname: Carlini
authors.forename: Paola
authors.initials: P
authors.lastname: Papaldo
authors.forename: Alessandra
authors.initials: A
authors.lastname: Fabi
authors.forename: Alessandra
authors.initials: A
authors.lastname: Felici
authors.forename: Enzo Maria
authors.initials: EM
authors.lastname: Ruggeri
authors.forename: Michele
authors.initials: M
authors.lastname: Milella
authors.forename: Mariangela
authors.initials: M
authors.lastname: Ciccarese
authors.forename: Carmen
authors.initials: C
authors.lastname: Nuzzo
authors.forename: Francesco
authors.initials: F
authors.lastname: Cognetti
authors.forename: Gianluigi
authors.initials: G
authors.lastname: Ferretti
mesh_terms: D000077384:Anastrozole; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects* / Q000627:therapeutic use; D001943:Breast Neoplasms / Q000188:drug therapy / Q000473:pathology; D056486:Chemical and Drug Induced Liver Injury / Q000201:enzymology* / Q000209:etiology*; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism*; D004347:Drug Interactions; D005260:Female; D000077156:Gefitinib; D006801:Humans; D007527:Isoenzymes / Q000378:metabolism; D008207:Lymphatic Metastasis; D008875:Middle Aged; D009570:Nitriles / Q000008:administration & dosage / Q000009:adverse effects; D011799:Quinazolines / Q000008:administration & dosage / Q000009:adverse effects; D014230:Triazoles / Q000008:administration & dosage / Q000009:adverse effects
chemical_list: D007527:Isoenzymes; D009570:Nitriles; D011799:Quinazolines; D014230:Triazoles; D000077384:Anastrozole; D003577:Cytochrome P-450 Enzyme System; D000077156:Gefitinib