Emerging vascular applications of magnetic resonance imaging: a picture is worth more than a thousand words.
Vascular applications of magnetic resonance (MR) imaging are reviewed, with emphasis on algorithms that use nonpictorial information contained in the MR data set. Current clinical vascular practice generally limits use of MR angiography and three-dimensional vessel images to qualitative pictorial rendering without routinely using the available quantitative information contained within the MR data. This review is dedicated to recent advances that include characterization of vessel histology, assessment of carotid plaque vulnerability, characterization of blood flow dynamics, quantitative analysis of disease severity, and prediction of vascular intervention outcome. Examples from histologic preparation, in vitro and in vivo experiments, are discussed, with an emphasis on potential clinical applications and advances in acquisition technology.
Fitzgerald
Tamara N
TN
Department of Surgery, Yale University School of Medicine, New Haven, CT 06519, USA.
Muto
Akihito
A
Kudo
Fabio Akimaro
FA
Pimiento
Jose Mario
JM
Constable
Robert Todd
RT
Dardik
Alan
A
D000465:Algorithms; D050197:Atherosclerosis / Q000175:diagnosis* / Q000503:physiopathology / Q000601:surgery; D001783:Blood Flow Velocity; D001808:Blood Vessels / Q000473:pathology* / Q000503:physiopathology; D006801:Humans; D007090:Image Interpretation, Computer-Assisted; D021621:Imaging, Three-Dimensional; D018810:Magnetic Resonance Angiography / Q000639:trends; D053783:Magnetic Resonance Imaging, Interventional / Q000639:trends; D018579:Patient Selection; D012039:Regional Blood Flow; D012720:Severity of Illness Index; D016896:Treatment Outcome; D014656:Vascular Surgical Procedures