title: MPO-ANCA-positive Wegener's granulomatosis presenting with hypertrophic cranial pachymeningitis: case report and review of the literature.
abstract: We describe a case of hypertrophic cranial pachymeningitis (HCP) associated with Wegener's granulomatosis (WG) in a 60-year-old man presenting with chronic headache and multiple cranial nerve neuropathies. A test for antibodies to the neutrophil cytoplasmic protein myeloperoxidase (MPO-ANCA) was positive in this case. We review the literature on perinuclear (p)-ANCA-related HCP, including our case. This case indicates the link between MPO-ANCA-positive WG and HCP.
authors.affiliation: Department of Medicine and Biosystemic Science, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan.
authors.forename: Mitsuteru
authors.initials: M
authors.lastname: Akahoshi
authors.forename: Goichi
authors.initials: G
authors.lastname: Yoshimoto
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Nakashima
authors.forename: Katsuhisa
authors.initials: K
authors.lastname: Miyake
authors.forename: Yasushi
authors.initials: Y
authors.lastname: Inoue
authors.forename: Yosuke
authors.initials: Y
authors.lastname: Tanaka
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Tsukamoto
authors.forename: Takahiko
authors.initials: T
authors.lastname: Horiuchi
authors.forename: Takeshi
authors.initials: T
authors.lastname: Otsuka
authors.forename: Mine
authors.initials: M
authors.lastname: Harada