title: [The effect of entomopathogenic fungi on the activity of detoxicating enzymes of larvae of bee pyralid Galleria mellonella L. (Lepidoptera, Pyralidee) and the role of detoxicating enzymes in the formation of the insect' resistance to entomopathogenic fungi].
abstract: In the work it was shown that fungal infection of insects increased the total esterase and glutathione-S-transferase activities of hemolymph. Acid and alkaline phosphatase activity in infected larvae remained at the same level as in intact larvae. Fungi-infected bee pyralid larvae turned out to be 1.46 times more resistant to phosphoorganic insecticide malation as compared to intact larvae. On the other hand, treating insects with the inhibitors of detoxicating enzymes caused a sharp decrease in the insects' resistance to entomophathogenic fungi. The work discusses possible participation of detoxicating enzymes in the formation of the insects' resistance to entomopathogenic fungi as well as new strategies of the development and creation of complex biopreparations based on entomopathogenic microorganisms and inhibitors of detoxicating enzymes.
authors.forename: V V
authors.initials: VV
authors.lastname: Serebrov
authors.forename: O N
authors.initials: ON
authors.lastname: Gerber
authors.forename: A A
authors.initials: AA
authors.lastname: Maliarchuk
authors.forename: V V
authors.initials: VV
authors.lastname: Martem'ianov
authors.forename: A A
authors.initials: AA
authors.lastname: Alekseev
authors.forename: V V
authors.initials: VV
authors.lastname: Glupov
mesh_terms: D000818:Animals; D005982:Glutathione Transferase / Q000378:metabolism; D006458:Hemolymph / Q000201:enzymology / Q000382:microbiology; D007305:Insecticide Resistance / Q000502:physiology; D007306:Insecticides / Q000378:metabolism / Q000494:pharmacology; D007814:Larva / Q000378:metabolism; D007915:Lepidoptera / Q000201:enzymology* / Q000382:microbiology; D052981:Metarhizium; D010572:Pest Control, Biological / Q000379:methods
chemical_list: D007306:Insecticides; D005982:Glutathione Transferase