title: Neuro-Behçets/neuro-Sweets disease presents simultaneously with severe tonsillitis, and features mimicking bacterial meningitis with skin lesions.
abstract: The patient was hospitalized due to rapidly undulant fever and sore throat. Empirical antibiotic therapy was started, however, headache also occurred. Lumbar puncture disclosed polynuclear leukocyte-predominant pleocytosis indicating that the patient suffered from bacterial meningitis. The antibiotics therapy was increased, however, consciousness became impaired and erythema multiforme-like skin lesions appeared. T2-weighted brain magnetic resonance imaging showed high signal intensity in the brainstem. HLA testing revealed B54 and Cw1. The patient presented futures of Behçets disease at the same time as those of Sweets syndrome and it was difficult to distinguish between the two diseases. Administration of prednisolone showed remarkable effect.
authors.affiliation: Department of Neurology, Nissan Tamagawa Hospital, Bunkyo-ku, Tokyo, Japan.
authors.forename: Taiji
authors.initials: T
authors.lastname: Tsunemi
authors.forename: Yuki
authors.initials: Y
authors.lastname: Sakai
authors.forename: Koichi
authors.initials: K
authors.lastname: Tsunoda
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Irie
authors.forename: Yoshiaki
authors.initials: Y
authors.lastname: Wada
mesh_terms: D000328:Adult; D001528:Behcet Syndrome / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D001921:Brain / Q000473:pathology; D002493:Central Nervous System Diseases / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D003937:Diagnosis, Differential; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D016920:Meningitis, Bacterial / Q000175:diagnosis*; D011239:Prednisolone / Q000627:therapeutic use; D012871:Skin Diseases / Q000175:diagnosis*; D016463:Sweet Syndrome / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D014069:Tonsillitis / Q000209:etiology*
chemical_list: D005938:Glucocorticoids; D011239:Prednisolone