title: [Molecular characterization of HTLV-1 among patients with tropical spastic paraparesis/HTLV-1 associated myelopathy in Belém, Pará].
abstract: The present study evaluated the occurrence of HTLV-1 and its subtypes in blood samples of patients presenting symptoms of tropical spastic paraparesis/HTLV-1 associated myelopathy. The detection of HTLV infection was performed by serological and molecular assays. Five patients were infected by HTLV-1 of the Cosmopolitan subtype, subgroup Transcontinental. The results confirm the occurrence of HTLV-1 infection among patients with clinical diagnosis of tropical spastic paraparesis/HTLV-1 associated myelopathy in Belém, Pará.
authors.affiliation: Laboratório de Virologia, Departamento de Patologia, Centro de Ciências Biológicas, Universidade Federal do Pará, Belém, PA.
authors.forename: Lucinda A
authors.initials: LA
authors.lastname: Souza
authors.forename: Ivina G L
authors.initials: IG
authors.lastname: Lopes
authors.forename: Eduardo Leitão
authors.initials: EL
authors.lastname: Maia
authors.forename: Vânia N
authors.initials: VN
authors.lastname: Azevedo
authors.forename: Luiz Fernando A
authors.initials: LF
authors.lastname: Machado
authors.forename: Marluísa O G
authors.initials: MO
authors.lastname: Ishak
authors.forename: Ricardo
authors.initials: R
authors.lastname: Ishak
authors.forename: Antonio Carlos R
authors.initials: AC
authors.lastname: Vallinoto
mesh_terms: D001483:Base Sequence; D004279:DNA, Viral / Q000032:analysis; D004797:Enzyme-Linked Immunosorbent Assay; D015368:Human T-lymphotropic virus 1 / Q000235:genetics*; D006801:Humans; D008969:Molecular Sequence Data; D015493:Paraparesis, Tropical Spastic / Q000175:diagnosis / Q000821:virology*; D016133:Polymerase Chain Reaction; D016415:Sequence Alignment
chemical_list: D004279:DNA, Viral