title: [Expression of BDNF and trk B in the cochleas of the aged rats].
abstract: OBJECTIVE
  To explore the correlation between the expression of brain derived neurotrophic factor (BDNF) and presbycusis in the cochleae of the aged rats.
  
  
  METHODS
  The mRNA expression of BDNF and presbycusis in the cochleas of the aged rats was quantitated by real time PCR.
  
  
  RESULTS
  The expression of BDNF in the cochleas of the aged rats with presbycusis was obviously less than that in the control group. And the difference was statistically significant.
  
  
  CONCLUSIONS
  The expression of BDNF is closely correlated to presbycusis in the aged rats.
authors.affiliation: Department of Otolaryngology, First Hospital of Harbin Medical University, Harbin 150001, China.
authors.forename: Yuru
authors.initials: Y
authors.lastname: Li
authors.forename: Delong
authors.initials: D
authors.lastname: Liu
authors.forename: Yuanyuan
authors.initials: Y
authors.lastname: Zhang
authors.forename: Ping
authors.initials: P
authors.lastname: Wang
authors.forename: Baodong
authors.initials: B
authors.lastname: Du
mesh_terms: D000375:Aging; D000818:Animals; D019208:Brain-Derived Neurotrophic Factor / Q000378:metabolism*; D003051:Cochlea / Q000378:metabolism*; D051381:Rats; D017208:Rats, Wistar; D020813:Receptor, trkB / Q000378:metabolism*
chemical_list: D019208:Brain-Derived Neurotrophic Factor; D020813:Receptor, trkB