title: Postpartum hemorrhage.
abstract: Postpartum hemorrhage (PPH) is the most important single cause of maternal death in both developing and developed countries. It arises from abnormalities in one of four basic processes, with uterine atony being the most common. A multidisciplinary approach to management is important. The value of oxytocin and prostaglandins, including misoprostol, in treatment is discussed. Recently developed, less invasive treatment options, namely uterine tamponade and compression sutures, are fast becoming valuable alternatives to the traditional options of pelvic devascularization and hysterectomy. With a stark contrast in maternal mortality from PPH between the developing and developed countries, public health strategies and medical interventions intended to minimize this are further discussed.
authors.affiliation: Department of Obstetrics and Gynaecology, St George's Hospital Medical School, London UK.
authors.forename: Gowri
authors.initials: G
authors.lastname: Ramanathan
authors.affiliation: Department of Obstetrics and Gynaecology, St George's Hospital Medical School, London UK.
authors.forename: Sabaratnam
authors.initials: S
authors.lastname: Arulkumaran
mesh_terms: D004621:Embolization, Therapeutic; D005260:Female; D006801:Humans; D007044:Hysterectomy; D010121:Oxytocin / Q000627:therapeutic use*; D006473:Postpartum Hemorrhage / Q000401:mortality* / Q000517:prevention & control / Q000628:therapy; D011247:Pregnancy; D011453:Prostaglandins / Q000627:therapeutic use*; D011634:Public Health; D013536:Suture Techniques; D014599:Uterus / Q000098:blood supply / Q000601:surgery; D016387:Women's Health
chemical_list: D011453:Prostaglandins; D010121:Oxytocin