title: Myeloproliferative disease in the pathogenesis and survival of Budd-Chiari syndrome.
abstract: We studied the etiology, diagnosis and natural course of myeloproliferative disease (MPD) in 40 consecutive patients with Budd-Chiari syndrome (BCS). In 38% of the BCS patients with MPD another etiological factor was found. JAK2 mutation was present in 41% of the tested BCS patients. Survival was not significantly affected by the presence of MPD.
authors.forename: Jasper H
authors.initials: JH
authors.lastname: Smalberg
authors.forename: Sarwa
authors.initials: S
authors.lastname: Darwish Murad
authors.forename: Eric
authors.initials: E
authors.lastname: Braakman
authors.forename: Peter J
authors.initials: PJ
authors.lastname: Valk
authors.forename: Harry L A
authors.initials: HL
authors.lastname: Janssen
authors.forename: Frank W G
authors.initials: FW
authors.lastname: Leebeek
mesh_terms: D000328:Adult; D006502:Budd-Chiari Syndrome / Q000209:etiology* / Q000401:mortality*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009196:Myeloproliferative Disorders / Q000150:complications* / Q000401:mortality*; D016019:Survival Analysis