title: Synthesis of perylene-labeled base-discriminating fluorescent (BDF) nucleoside and its fluorescence properties.
abstract: We have synthesized perylene labeled BDF probe and its photophysical properties were explored. Perylene labeled oligonucleotide probe is capable of detecting cytosine from its target mismatch sequence by enhancement of fluorescence intensity.
authors.affiliation: Newcat Institute, School of Engineering, Nihon University, Tamura, Koriyama, Fukushima 963-8642, Japan.
authors.forename: Subhendu Sekhar
authors.initials: SS
authors.lastname: Bag
authors.forename: Yoshio
authors.initials: Y
authors.lastname: Saito
authors.forename: Kazuo
authors.initials: K
authors.lastname: Hanawa
authors.forename: Keigo
authors.initials: K
authors.lastname: Hayasi
authors.forename: Satoshi
authors.initials: S
authors.lastname: Kodate
authors.forename: Isamu
authors.initials: I
authors.lastname: Suzuka
authors.forename: Isao
authors.initials: I
authors.lastname: Saito
mesh_terms: D005456:Fluorescent Dyes / Q000138:chemical synthesis / Q000737:chemistry*; D015345:Oligonucleotide Probes / Q000138:chemical synthesis / Q000737:chemistry*; D010569:Perylene / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000737:chemistry; D013050:Spectrometry, Fluorescence; D014529:Uridine / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000737:chemistry
chemical_list: C522090:2'-deoxy-5-(3-(3-perylenecarboxamido)propynyl)uridine; D005456:Fluorescent Dyes; D015345:Oligonucleotide Probes; D010569:Perylene; D014529:Uridine