title: Pseudo-organ boundary conditions applied to a computational fluid dynamics model of the human aorta.
abstract: In three-dimensional numerical studies of the aorta, it is difficult to apply proper boundary conditions at the end of each major aortic branch because of interactions between blood and organs. Organs and body parts were assumed to be likened to cylindrically shaped porous media, so-called pseudo-organs, and treated in the computational domain as forms of hemodynamic resistance. Permeability functions were determined from two-dimensional axisymmetric computations of each aortic branch and these functions were then used in an unsteady three-dimensional simulation of the complete aorta. Substantially accurate cardiac output (5.91 L/min) and blood distributions to the major branches were predicted.
authors.affiliation: Interdisciplinary Program in Biomedical Engineering Major, Seoul National University, Seoul, Republic of Korea.
authors.forename: Joong
authors.initials: J
authors.lastname: Yull Park
authors.forename: Chan
authors.initials: C
authors.lastname: Young Park
authors.forename: Chang
authors.initials: C
authors.lastname: Mo Hwang
authors.forename: Kyung
authors.initials: K
authors.lastname: Sun
authors.forename: Byoung
authors.initials: B
authors.lastname: Goo Min
mesh_terms: D001011:Aorta / Q000033:anatomy & histology* / Q000502:physiology*; D001698:Biomedical Engineering; D001783:Blood Flow Velocity; D001794:Blood Pressure; D003198:Computer Simulation; D018056:Hemorheology; D006801:Humans; D008953:Models, Anatomic; D008955:Models, Cardiovascular; D012039:Regional Blood Flow; D014655:Vascular Resistance