title: msHOT: modifying Hudson's ms simulator to incorporate crossover and gene conversion hotspots.
abstract: We have incorporated both crossover and gene conversion hotspots into an existing coalescent-based program for simulating genetic variation data for a sample of chromosomes from a population.
  
  
  BACKGROUND
  The source code for msHOT is available at http://home.uchicago.edu/~rhudson1, along with accompanying instructions.
authors.affiliation: Department of Statistics, University of Oxford, 1 South Parks Road, Oxford OX1 3TG, UK. hellenth@stats.ox.ac.uk
authors.forename: Garrett
authors.initials: G
authors.lastname: Hellenthal
authors.forename: Matthew
authors.initials: M
authors.lastname: Stephens
mesh_terms: D000465:Algorithms; D002874:Chromosome Mapping / Q000379:methods*; D003434:Crossing Over, Genetic / Q000235:genetics*; D005785:Gene Conversion / Q000235:genetics*; D014644:Genetic Variation / Q000235:genetics*; D005828:Genetics, Population; D008957:Models, Genetic; D012984:Software