title: Analysis of veterinary drug residues in fish and shrimp composites collected during the Canadian Total Diet Study, 1993-2004.
abstract: Thirty shrimp, marine fish, freshwater fish, and canned fish composite samples collected and prepared as part of the Canadian Total Diet Study were analysed for 39 different veterinary drug residues. The analyses were undertaken to obtain baseline data that could be used to estimate the dietary exposure of Canadians to these residues. The most frequently observed residue was AOZ (four out of 30 samples), the metabolite of furazolidone, at a range of 0.50 to 2.0 ng g(-1) wet weight. Other residues detected included enrofloxacin (three samples; 0.3-0.73 ng g(-1)), leucomalachite green (three samples; 0.73-1.2 ng g(-1)), oxolinic acid (two samples; 0.3-4.3 ng g(-1)), AMOZ (the metabolite of furaltadone; one sample; 0.40 ng g(-1)), chloramphenicol (one sample; 0.40 ng g(-1)), and SEM (the metabolite of nitrofurazone; one sample; 0.8 ng g(-1)). The results of this survey indicate that Canadians are exposed to low ng g-1 concentrations of some banned and unapproved veterinary drug residues via the consumption of certain fish and shrimp.
authors.affiliation: Food Research Division, Health Canada, Ottawa, ON, Canada K1A 0L2. Sheryl_Tittlemier@hc-sc.gc.ca
authors.forename: S A
authors.initials: SA
authors.lastname: Tittlemier
authors.forename: J
authors.initials: J
authors.lastname: Van de Riet
authors.forename: G
authors.initials: G
authors.lastname: Burns
authors.forename: R
authors.initials: R
authors.lastname: Potter
authors.forename: C
authors.initials: C
authors.lastname: Murphy
authors.forename: W
authors.initials: W
authors.lastname: Rourke
authors.forename: H
authors.initials: H
authors.lastname: Pearce
authors.forename: X L
authors.initials: XL
authors.lastname: Cao
authors.forename: R W
authors.initials: RW
authors.lastname: Dabekai
authors.forename: G
authors.initials: G
authors.lastname: Dufresne
mesh_terms: D000818:Animals; D017756:Aquaculture; D002170:Canada; D004350:Drug Residues / Q000032:analysis*; D005399:Fishes / Q000378:metabolism; D005504:Food Analysis / Q000379:methods; D005506:Food Contamination / Q000032:analysis*; D033561:Penaeidae / Q000378:metabolism; D017747:Seafood / Q000032:analysis*; D019155:Veterinary Drugs / Q000032:analysis*
chemical_list: D019155:Veterinary Drugs