title: Revascularization of the right coronary artery: influence on thermodilution right ventricular ejection fraction.
abstract: This study was designed in order to evaluate the influence of right coronary artery (RCA) disease and its revascularization on right heart performance monitored by measuring thermodilution right ventricular ejection fraction (RVEF). Forty patients undergoing elective aortocoronary bypass surgery were divided into two groups: group 1, with RCA revascularization, n=20; and group 2, without RCA disease or revascularization, n=20. RVEF was measured using a pulmonary arterial catheter mounted with a fast-response thermistor and a bedside microprocessor ejection fraction computer. The major finding of the study was that myocardial revascularization with extracorporeal circulation was followed by a decrease in RVEF which was significantly more pronounced in group 1 (-13.1%) in comparison to group 2 (-5.0%). RVEF gradually increased after bypass, but did not reach baseline values. By the first postoperative day, RVEF had reached baseline values again in group 1 and had increased beyond baseline values in group 2. Traditionally measured hemodynamic parameters could not be correlated with the course of RVEF, except for cardiac index. The present study further suggests that right-sided events may have clinical effects on left-sided function. Inadequate protection of the right heart, especially in patients with RCA stenosis, may result in depression of right ventricular myocardial performance, which can be monitored serially by measuring RVEF.
authors.affiliation: Department of Anesthesiology, Justus-Liebig-University of Giessen, FRG.
authors.forename: J
authors.initials: J
authors.lastname: Boldt
authors.forename: D
authors.initials: D
authors.lastname: Kling
authors.forename: A
authors.initials: A
authors.lastname: Thiel
authors.forename: H H
authors.initials: HH
authors.lastname: Scheld
authors.forename: G
authors.initials: G
authors.lastname: Hempelmann
mesh_terms: D001794:Blood Pressure; D002315:Cardiopulmonary Bypass / Q000379:methods; D003324:Coronary Artery Disease / Q000601:surgery*; D003331:Coronary Vessels / Q000473:pathology / Q000601:surgery*; D017558:Elective Surgical Procedures / Q000379:methods; D006339:Heart Rate; D006352:Heart Ventricles; D006801:Humans; D008875:Middle Aged; D009204:Myocardial Revascularization / Q000379:methods*; D013318:Stroke Volume; D013815:Thermodilution / Q000379:methods; D013997:Time Factors