title: Water-selective spectral-spatial contrast-enhanced breast MRI for cancer detection in patients with extracapsular and injected free silicone.
abstract: OBJECTIVE
  This study investigates the use of contrast-enhanced, T1-weighted, water-selective spectral-spatial 3D gradient echo magnetic resonance imaging (MRI) with magnetization transfer (3DSSMT) for detecting breast cancer in patients with intraparenchymal silicone.
  
  
  CONCLUSIONS
  Water-selective 3DSSMT provides superior fat and silicone suppression in patients with free silicone as compared with conventional fat saturation. It enables direct, high-quality, high-spatial-resolution, T1-weighted breast MRI of contrast enhancement without the need for subtraction processing and aids diagnosis of cancer in the breast with free silicone.
authors.affiliation: New York University, Department of Radiology, 560 First Avenue, New York, NY 10016, USA.
authors.forename: Julia
authors.initials: J
authors.lastname: Po
authors.forename: Daniel J A
authors.initials: DJ
authors.lastname: Margolis
authors.forename: Charles H
authors.initials: CH
authors.lastname: Cunningham
authors.forename: Robert J
authors.initials: RJ
authors.lastname: Herfkens
authors.forename: Debra M
authors.initials: DM
authors.lastname: Ikeda
authors.forename: Bruce L
authors.initials: BL
authors.lastname: Daniel
mesh_terms: D000328:Adult; D000368:Aged; D018427:Breast Implants; D001943:Breast Neoplasms / Q000175:diagnosis*; D003287:Contrast Media; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008875:Middle Aged; D012189:Retrospective Studies; D020034:Silicone Gels; D014867:Water
chemical_list: D003287:Contrast Media; D020034:Silicone Gels; D014867:Water