Function of AGCA tetrads in (CAG)n repeats.
We investigate the structural properties of d(CAG)n repeats in d[CG(CAG)4CG)]*d[CG(CTG)4CG]. The crystals diffract up to 3.5 A and completeness of data is only 60%. We also measure Tm-UV and CD spectra and gel electrophoresis of this oligomer.
Grzeskowiak
Kazimierz
K
Osaka University of Pharmaceutical Sciences, 4-20-1 Nasahara, Takatsuki, Osaka 569-1094, Japan.
Sawaya
Michael R
MR
Ohishi
Hirofumi
H
Tomoo
Koji
K
Ishida
Toshimasa
T
D001483:Base Sequence; D002942:Circular Dichroism; D018360:Crystallography, X-Ray; D004247:DNA / Q000737:chemistry* / Q000235:genetics; D004587:Electrophoresis, Agar Gel; D008969:Molecular Sequence Data; D013056:Spectrophotometry, Ultraviolet; D044366:Transition Temperature; D018911:Trinucleotide Repeats
D004247:DNA