[Neurological complications of lymphomas].
Peripheral neurological complications of lymphomas are rare, but all types of neuropathy can be observed in the context of lymphoma. This great clinical heterogeneity can be related to the variety of pathological processes that can affect the peripheral nerve or be linked to the different subtypes of lymphoma. In addition to the common causes of peripheral nerve involvement, such as iatrogenic toxicity, there are mechanisms that are more specifically related to lymphomas, such as nerve tumor infiltration, or dysimmune perturbations induced by the hemopathy. These dysimmune processes can result in various neuropathies, such as inflammatory demyelinating polyradiculoneuropathy, or neuropathies secondary to the secretion of a monoclonal immunoglobulin. Identifying the mechanism of the neuropathy is necessary in order to determine the therapeutic options and to improve the prognosis.
Viala
K
K
Fédération de Neurophysiologie Clinique, Assistance des Hôpitaux de Paris (APHP), Université Paris VI. karine.viala@psl.ap-hop-paris.fr
D000911:Antibodies, Monoclonal / Q000032:analysis; D006801:Humans; D007249:Inflammation; D008223:Lymphoma / Q000150:complications* / Q000276:immunology / Q000473:pathology; D009046:Motor Neurons / Q000473:pathology / Q000502:physiology; D010523:Peripheral Nervous System Diseases / Q000209:etiology* / Q000276:immunology / Q000473:pathology
D000911:Antibodies, Monoclonal