title: Insights into the general and efficient cross McMurry reactions between ketones.
abstract: The selective cross McMurry couplings of diaryl or aryl ketones with various substituted ketones were achieved in 53-94% isolated yields. It is believed that the strong affinity of the substituents to the low-valent titanium surface plays an important role in regards to moderating selectivity. Through the introduction of such substituents followed by their removal post McMurry coupling, structurally similar ketones can be effectively cross-coupled.
authors.affiliation: Department of Chemistry, Beijing Normal University, Beijing, 100875, China. xinfangduan@vip.163.com
authors.forename: Xin-Fang
authors.initials: XF
authors.lastname: Duan
authors.forename: Jing
authors.initials: J
authors.lastname: Zeng
authors.forename: Jia-Wei
authors.initials: JW
authors.lastname: Lü
authors.forename: Zhan-Bin
authors.initials: ZB
authors.lastname: Zhang
mesh_terms: D001555:Benzene Derivatives / Q000138:chemical synthesis* / Q000737:chemistry; D007659:Ketones / Q000737:chemistry*; D015394:Molecular Structure; D013237:Stereoisomerism; D014025:Titanium / Q000737:chemistry
chemical_list: D001555:Benzene Derivatives; D007659:Ketones; D014025:Titanium