title: Extended bleaching of tetracycline-stained teeth: a 5-year study.
abstract: Bleaching tetracycline-stained teeth is the most challenging form of tooth lightening. This article reports on 44 subjects who bleached their tetracycline-stained teeth for 6 months using trays with reservoirs overnight in a half-mouth designed study and 2 of 3 different concentrations of carbamide peroxide (10%, 15% or 20%). The subjects were followed for 5 years. The area evaluated was the middle third of the teeth. More than 55% of tooth lightening occurred within 1 month; after 5 years, more than 65% of the maximum tooth whitening remained for all 3 gel concentrations. Tooth whitening can be accomplished with any of the 3 concentrations used.
authors.affiliation: Department of Restorative Dentistry, Indiana University School of Dentistry, Indianapolis, IN, USA.
authors.forename: Bruce A
authors.initials: BA
authors.lastname: Matis
authors.forename: Yining
authors.initials: Y
authors.lastname: Wang
authors.forename: George J
authors.initials: GJ
authors.lastname: Eckert
authors.forename: Michael A
authors.initials: MA
authors.lastname: Cochran
authors.forename: Tao
authors.initials: T
authors.lastname: Jiang
mesh_terms: D000704:Analysis of Variance; D000900:Anti-Bacterial Agents / Q000009:adverse effects*; D000077463:Carbamide Peroxide; D003124:Colorimetry; D003742:Dental Devices, Home Care; D003807:Dentin Sensitivity / Q000139:chemically induced; D004305:Dose-Response Relationship, Drug; D004338:Drug Combinations; D006801:Humans; D008137:Longitudinal Studies; D016877:Oxidants / Q000008:administration & dosage / Q000009:adverse effects; D017060:Patient Satisfaction; D010545:Peroxides / Q000008:administration & dosage / Q000009:adverse effects; D011795:Surveys and Questionnaires; D013752:Tetracycline / Q000009:adverse effects*; D014073:Tooth Bleaching / Q000009:adverse effects / Q000295:instrumentation / Q000379:methods*; D019237:Tooth Cervix / Q000473:pathology; D014075:Tooth Discoloration / Q000139:chemically induced* / Q000188:drug therapy*; D014508:Urea / Q000008:administration & dosage / Q000009:adverse effects / Q000031:analogs & derivatives
chemical_list: D000900:Anti-Bacterial Agents; D004338:Drug Combinations; D016877:Oxidants; D010545:Peroxides; D000077463:Carbamide Peroxide; D014508:Urea; D013752:Tetracycline