[Prognostic models for Hodgkin's disease].
A prognostic model for Hodgkin's disease was worked out using the data on disease-free survival among patients receiving 4-8 courses of COOP(MOPP)/ABVD plus (sub)total irradiation. Patients with stage I-II Hodgkin's disease (less then 4 lesions) without large involved mediastinal masses, intoxication symptoms and focal splenic involvement were referred to the favorable prognosis group. The poor prognosis group featured stage III(2)-IV tumor as well as large masses of involved mediastinal tissue, focal splenic involvement at any stage plus 7 or more lesions. An assessment of tumor advancement across lesions is more significant for radiotherapy planning rather than that of organ involvement. It is reasonable to distinguish two substages--III(1) and III(2). Our model was compared with GHSG and it was suggested that ways be found to use both of them in prognosing of disease outcome.
Panyshin
G A
GA
Datsenko
P V
PV
Sotnikov
V M
VM
Mel'nik
Iu D
IuD
D006689:Hodgkin Disease / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D015233:Models, Statistical; D009367:Neoplasm Staging; D011379:Prognosis