title: [Local mechanisms of the regulatory action of Scutellaria baicalensis and ginseng extracts on the erythropoiesis after paradoxical sleep deprivation].
abstract: The influence of ginseng and skullcap (Scutellaria baicalensis) extracts on the local mechanisms of erythropoiesis control under the conditions paradoxical sleep deprivation has been studied. The regulatory action of both preparations on the bone marrow erythropoiesis is based on their ability to influence the proliferation and differentiation in erythroid cells-precursors via modulation of the functional activity of cellular hemopoiesis-inducing microenvironment elements. In particular, the drugs induce changes in the structural and functional organization of the bone marrow and in the production of short-range humoral erythropoiesis regulatory elements.
authors.forename: N V
authors.initials: NV
authors.lastname: Provalova
authors.forename: N I
authors.initials: NI
authors.lastname: Suslov
authors.forename: E G
authors.initials: EG
authors.lastname: Skurikhin
authors.forename: A M
authors.initials: AM
authors.lastname: Dygaĭ
mesh_terms: D000818:Animals; D001853:Bone Marrow / Q000187:drug effects; D015672:Erythroid Precursor Cells / Q000166:cytology / Q000187:drug effects*; D004920:Erythropoiesis / Q000187:drug effects*; D051379:Mice; D008808:Mice, Inbred CBA; D005894:Panax / Q000737:chemistry*; D010936:Plant Extracts / Q000494:pharmacology*; D031364:Scutellaria baicalensis / Q000737:chemistry*; D012892:Sleep Deprivation / Q000503:physiopathology; D012895:Sleep, REM
chemical_list: D010936:Plant Extracts