[Metachronous adrenal metastasis in two patients undergoing radical nephrectomy for primary renal cell carcinoma].
OBJECTIVE
We report two exceptional cases of metachronous adrenal metastasis of renal cell carcinomas and perform a bibliographic review. After the evaluation of various features such as frequency, etiopathogenesis, diagnosis and follow-up of these patients we conclude that these metastases are rare, and they usually appear late in the evolution of patients with low stage renal cell carcinoma.


CONCLUSIONS
Once reviewed the treatment and checked the absence of guidelines for the therapeutic management of these patients we propose surgery for the adrenal metastasis as well as adjuvant treatment with immunotherapy.
Rosales Leal
José Luis
JL
Servio de Urología, Hospital Universitario Virgen de las Nieves, Granada, España. jrosal@fundacionhvn.org
Rodríguez Herrera
Francisco
F
Ortiz Gorráiz
Manuel
M
Honrubia Vílchez
Beatriz
B
Fernández Sánchez
Antonio
A
Vázquez Alonso
Fernando
F
Pascual Geler
Manrique
M
Martínez Morcillo
Antonio
A
Vicente Prados
Javier
J
Cózar Olmo
José Manuel
JM
Espejo Maldonado
Eduardo
E
Tallada Buñuel
Miguel
M
D000310:Adrenal Gland Neoplasms / Q000556:secondary*; D000368:Aged; D002292:Carcinoma, Renal Cell / Q000556:secondary* / Q000601:surgery*; D005260:Female; D006801:Humans; D007680:Kidney Neoplasms / Q000473:pathology* / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D009392:Nephrectomy