title: A method for classification of transient events in EEG recordings: application to epilepsy diagnosis.
abstract: OBJECTIVE
  The aim of the paper is to analyze transient events in inter-ictal EEG recordings, and classify epileptic activity into focal or generalized epilepsy using an automated method.
  
  
  METHODS
  A two-stage approach is proposed. In the first stage the observed transient events of a single channel are classified into four categories: epileptic spike (ES), muscle activity (EMG), eye blinking activity (EOG), and sharp alpha activity (SAA). The process is based on an artificial neural network. Different artificial neural network architectures have been tried and the network having the lowest error has been selected using the hold out approach. In the second stage a knowledge-based system is used to produce diagnosis for focal or generalized epileptic activity.
  
  
  RESULTS
  The classification of transient events reported high overall accuracy (84.48%), while the knowledge-based system for epilepsy diagnosis correctly classified nine out of ten cases.
  
  
  CONCLUSIONS
  The proposed method is advantageous since it effectively detects and classifies the undesirable activity into appropriate categories and produces a final outcome related to the existence of epilepsy.
authors.affiliation: Dept. of Medical Physics, Medical School, University of Ioannina, Ioannina, Greece.
authors.forename: A T
authors.initials: AT
authors.lastname: Tzallas
authors.forename: P S
authors.initials: PS
authors.lastname: Karvelis
authors.forename: C D
authors.initials: CD
authors.lastname: Katsis
authors.forename: D I
authors.initials: DI
authors.lastname: Fotiadis
authors.forename: S
authors.initials: S
authors.lastname: Giannopoulos
authors.forename: S
authors.initials: S
authors.lastname: Konitsiotis
mesh_terms: D000200:Action Potentials; D004569:Electroencephalography; D004827:Epilepsy / Q000175:diagnosis* / Q000503:physiopathology; D005240:Feasibility Studies; D006801:Humans; D051188:Knowledge Bases; D016571:Neural Networks, Computer; D017603:Signal Detection, Psychological; D013997:Time Factors