Allylpalladium umpolung in the three-component coupling synthesis of homoallylic amines.
[Structure: see text] Homoallylic amines and alpha-amino esters were prepared via a Pd(II)-catalyzed coupling of boronic acids and 1,2-nonadiene with ethyl iminoacetate or aliphatic, aromatic, and heteroaromatic imines. The allylpalladium umpolung was induced by a Pd(OAc)2 catalyst with commercial phosphine ligands.
Hopkins
Chad D
CD
Department of Chemistry, University of Kansas, 1251 Wescoe Hall Drive, Lawrence, Kansas 66045-7582, USA.
Malinakova
Helena C
HC
D000588:Amines / Q000138:chemical synthesis*; D001897:Boronic Acids / Q000737:chemistry; D002384:Catalysis; D010165:Palladium / Q000737:chemistry*
D000588:Amines; D001897:Boronic Acids; D010165:Palladium