Synthesis of oligo(ethylene glycol) toward 44-mer.
A synthetic method for oligo(ethylene glycol) toward 44-mer (FW = 1956.35) is described. Reiteration of Williamson's ether synthesis and hydrogenation to remove protecting benzyl group affords desired oligo(ethylene glycol) toward 44-mer in moderate yields. The advantages in this method are use of commercially easily available materials as starting materials and procedures avoiding difficulty in purification of the products as much as possible.
Ahmed
Saleh A
SA
Institute for Biological Resources and Functions, AIST, Central 5, 1-1-1, Higashi, Tsukuba, Ibaraki 305-8565, Japan.
Tanaka
Mutsuo
M
D015394:Molecular Structure; D008970:Molecular Weight; D011092:Polyethylene Glycols / Q000138:chemical synthesis* / Q000737:chemistry
D011092:Polyethylene Glycols