title: Improved performance of a DNA nanomachine by cationic copolymers.
abstract: We have reported previously that the cationic comb-type copolymer, PLL-g-Dex, accelerated DNA strand exchange reaction while stabilizing DNA duplexes. In this research, we studied the effects of PLL-g-Dex on a DNA-fueled nanomachine. The copolymer enabled rapid and secure operations of the DNA nanomachine which utilized the structural transition between intramolecular G-quadruplex and intermolecular double helix.
authors.affiliation: Department of Biomolecular Engineering, Graduate School of Biosdence and Biotechnology, Tokyo Institute of Technology.
authors.forename: Naoki
authors.initials: N
authors.lastname: Makita
authors.forename: Satoru
authors.initials: S
authors.lastname: Inoue
authors.forename: Toshihiro
authors.initials: T
authors.lastname: Akaike
authors.forename: Atsushi
authors.initials: A
authors.lastname: Maruyama
mesh_terms: D004247:DNA / Q000737:chemistry*; D003911:Dextrans / Q000737:chemistry*; D053758:Nanoparticles / Q000737:chemistry*; D011107:Polylysine / Q000737:chemistry*
chemical_list: D003911:Dextrans; D011107:Polylysine; D004247:DNA