title: [A case of Churg-Strauss syndrome discovered with hematemesis].
abstract: A 68-years-old Japanese woman was hospitalized emergently because of hemorrhagic gastric ulcer. For the hospitalization period, elevated levels of white blood cell count, eosinophilic leucocyte count, serum IgE and positive MPO-ANCA were recognized. With considering clinical course and these laboratory findings, we diagnosed Churg-Strauss syndrome (CSS). Steroid therapy in combination with cyclophosphamide was effective. CSS is a rare disease, but we should discriminate this disease when we encounter gastrointestinal bleeding of unknown etiology, especially PPI-resistant gastric ulcer.
authors.affiliation: Second Department of Internal Medicine, National Defense Medical College.
authors.forename: Keisuke
authors.initials: K
authors.lastname: Okudaira
authors.forename: Atsushi
authors.initials: A
authors.lastname: Kawaguchi
authors.forename: Ryota
authors.initials: R
authors.lastname: Hokari
authors.forename: Kazuyuki
authors.initials: K
authors.lastname: Narimatsu
authors.forename: Masaaki
authors.initials: M
authors.lastname: Higashiyama
authors.forename: Norikazu
authors.initials: N
authors.lastname: Mataki
authors.forename: Shingo
authors.initials: S
authors.lastname: Kato
authors.forename: Syunsuke
authors.initials: S
authors.lastname: Komoto
authors.forename: Yoshikazu
authors.initials: Y
authors.lastname: Tsuzuki
authors.forename: Shigeaki
authors.initials: S
authors.lastname: Nagao
authors.forename: Kazuro
authors.initials: K
authors.lastname: Itoh
authors.forename: Soichiro
authors.initials: S
authors.lastname: Miura
mesh_terms: D000368:Aged; D015267:Churg-Strauss Syndrome / Q000175:diagnosis* / Q000188:drug therapy; D003520:Cyclophosphamide / Q000008:administration & dosage; D004359:Drug Therapy, Combination; D005260:Female; D006396:Hematemesis / Q000209:etiology*; D006801:Humans; D008775:Methylprednisolone / Q000008:administration & dosage; D010438:Peptic Ulcer Hemorrhage / Q000150:complications*; D020551:Pulse Therapy, Drug; D013276:Stomach Ulcer / Q000150:complications*
chemical_list: D003520:Cyclophosphamide; D008775:Methylprednisolone