title: Electrochemical detection of single base mismatches in DNA using redox-modified oligonucleotides.
abstract: A facile synthesis of new anthraquinone (AQ)-modified oligonucleotides was described. The AQ-oligomer-bound electrode was used for the electrochemical detection of a single base mismatch in DNA.
authors.affiliation: Department of Materials Science and Chemistry, University of Hyogo, 2167 Shosha, Himeji 671-2201, Japan.
authors.forename: Narihisa
authors.initials: N
authors.lastname: Orino
authors.forename: Satoshi
authors.initials: S
authors.lastname: Kumamoto
authors.forename: Mitsunobu
authors.initials: M
authors.lastname: Nakamura
authors.forename: Kazushige
authors.initials: K
authors.lastname: Yamana
mesh_terms: D000880:Anthraquinones / Q000138:chemical synthesis / Q000737:chemistry*; D020137:Base Pair Mismatch; D004252:DNA Mutational Analysis / Q000295:instrumentation / Q000379:methods*; D004563:Electrochemistry; D004566:Electrodes; D015345:Oligonucleotide Probes / Q000737:chemistry*; D009943:Organophosphorus Compounds / Q000138:chemical synthesis / Q000737:chemistry*; D010084:Oxidation-Reduction
chemical_list: C520200:3-(9,10-anthraquinone-2-carboxamido)-2-cyanoethyl-4-(dimethoxytrityl)butoxy-N,N-diisopropylphosphoramidate; D000880:Anthraquinones; D015345:Oligonucleotide Probes; D009943:Organophosphorus Compounds