title: Skin chemistry of nudibranchs from the west coast of North America.
abstract: The Pacific coastline of North America extends from Alaska in the north to Panama in the south. Chemical studies of skin extracts from nudibranchs collected along this coast have resulted in the isolation of over 100 chemically diverse secondary metabolites. The majority of the compounds are terpenoids, but polyketides, steroids, and alkaloids have also been found. Observations of geographic variation in metabolite content and stable isotope-feeding experiments have provided information about the de novo biosynthetic or dietary sequestration origins of the skin extract metabolites.
authors.affiliation: Departments of Chemistry and Earth & Ocean Sciences, University of British Columbia V6T 1Z1 Vancouver, BC., Canada.
authors.forename: R J
authors.initials: RJ
authors.lastname: Andersen
authors.forename: K
authors.initials: K
authors.lastname: Desjardine
authors.forename: K
authors.initials: K
authors.lastname: Woods
mesh_terms: D000818:Animals; D001685:Biological Factors / Q000737:chemistry* / Q000493:pharmacokinetics; D005843:Geography; D008386:Marine Biology; D008974:Mollusca / Q000737:chemistry* / Q000145:classification; D009656:North America; D010140:Pacific Ocean; D012867:Skin / Q000737:chemistry*; D013045:Species Specificity; D013729:Terpenes / Q000737:chemistry* / Q000493:pharmacokinetics
chemical_list: D001685:Biological Factors; D013729:Terpenes