Effects of acute exercise and training on insulin action and sensitivity: focus on molecular mechanisms in muscle.
A single bout of exercise increases insulin sensitivity for several hours and the effect is mainly restricted to the muscles recruited during exercise. When exercise is repeated over time, adaptations to physical training occur that include more long-lasting increases in insulin sensitivity. The present review explores the molecular mechanisms involved in both the acute and chronic effects of exercise on insulin sensitivity in skeletal muscle.
Wojtaszewski
Jørgen F P
JF
Copenhagen Muscle Research Centre, Institute of Exercise and Sport Sciences, University of Copenhagen, Denmark.
Richter
Erik A
EA
D000818:Animals; D015444:Exercise / Q000502:physiology*; D005947:Glucose / Q000378:metabolism; D006801:Humans; D007328:Insulin / Q000378:metabolism; D007333:Insulin Resistance / Q000502:physiology*; D008954:Models, Biological; D009119:Muscle Contraction / Q000502:physiology; D018482:Muscle, Skeletal / Q000502:physiology*; D010806:Physical Education and Training; D005082:Physical Exertion / Q000502:physiology; D015398:Signal Transduction
D007328:Insulin; D005947:Glucose