title: Cirrhosis: CT and MR imaging evaluation.
abstract: In this article, we present the CT and MR imaging characteristics of the cirrhotic liver. We describe the altered liver morphology in different forms of viral, alcoholic and autoimmune end-stage liver disease. We present the spectrum of imaging findings in portal hypertension, such as splenomegaly, ascites and varices. We describe the patchy and lacelike patterns of fibrosis, along with the focal confluent form. The process of hepatocarcinogenesis is detailed, from regenerative to dysplastic nodules to overt hepatocellular carcinoma. Different types of non-neoplastic focal liver lesions occurring in the cirrhotic liver are discussed, including arterially enhancing nodules, hemangiomas and peribiliary cysts. We show different conditions causing liver morphology changes that can mimic cirrhosis, such as congenital hepatic fibrosis, "pseudo-cirrhosis" due to breast metastases treated with chemotherapy, Budd-Chiari syndrome, sarcoidosis and cavernous transformation of the portal vein.
authors.affiliation: Sezione di Radiologia, Ospedale Specializzato in Gastroenterologia, Saverio de Bellis-IRCCS, 70013 Castellana Grotte (Bari), Italy. gbranca@yahoo.com
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Brancatelli
authors.forename: Michael P
authors.initials: MP
authors.lastname: Federle
authors.forename: Roberta
authors.initials: R
authors.lastname: Ambrosini
authors.forename: Roberto
authors.initials: R
authors.lastname: Lagalla
authors.forename: Alessandro
authors.initials: A
authors.lastname: Carriero
authors.forename: Massimo
authors.initials: M
authors.lastname: Midiri
authors.forename: Valérie
authors.initials: V
authors.lastname: Vilgrain
mesh_terms: D006801:Humans; D008099:Liver / Q000000981:diagnostic imaging* / Q000473:pathology*; D008103:Liver Cirrhosis / Q000175:diagnosis*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D017410:Practice Guidelines as Topic; D010818:Practice Patterns, Physicians'; D014057:Tomography, X-Ray Computed / Q000379:methods*