Necrotic vasculitis in a patient with abdominal fibromatosis and Guillain-Barré syndrome.
The case of a 65-year-old woman presenting with Guillain-Barré syndrome is herein reported. Tomographic investigation revealed abdominal and retroperitoneal fibromatosis. During her hospitalization, renal involvement ensued, and subsequent renal biopsy demonstrated findings of crescentic pauci-immune glomerulonephritis negative for ANCA antibodies and with characteristics indicative of necrotic angiitis. The simultaneous existence of the three diseases in the same patient as well as the relation between necrotic vasculitis and G-B syndrome is speculated, and the relevant literature is reviewed.
Efstratiadis
Georgios
G
Department of Nephrology, Hippokration General Hospital, Ethnikis Aminis 14, Thessaloniki 54621, Greece. efstrati@med.auth.gr
Garyfallos
Alexander
A
Tsiaousis
Georgios
G
Jiavazis
Ignatios
I
Deretzi
Georgia
G
Leontsini
Maria
M
Venizelos
Ioannis
I
Memmos
Dimitrios
D
D000368:Aged; D019268:Antibodies, Antineutrophil Cytoplasmic / Q000097:blood; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D014408:Biomarkers, Tumor / Q000097:blood; D018394:CA-125 Antigen / Q000097:blood; D003520:Cyclophosphamide / Q000008:administration & dosage; D005260:Female; D018221:Fibromatosis, Abdominal / Q000150:complications* / Q000473:pathology; D020275:Guillain-Barre Syndrome / Q000150:complications* / Q000473:pathology; D006801:Humans; D007668:Kidney / Q000473:pathology; D008775:Methylprednisolone / Q000008:administration & dosage; D009336:Necrosis / Q000150:complications; D014057:Tomography, X-Ray Computed; D018084:Ultrasonography, Interventional; D014657:Vasculitis / Q000150:complications / Q000473:pathology*
D019268:Antibodies, Antineutrophil Cytoplasmic; D014408:Biomarkers, Tumor; D018394:CA-125 Antigen; D003520:Cyclophosphamide; D008775:Methylprednisolone