A rapid screening battery to identify frontal dysfunction in patients with ALS.
We studied the relationship between verbal associative fluency, verbal abstract reasoning, and judgment in ALS using a 20-minute screening evaluation. Deficiencies in these measures were found in 20.0%, 18.6%, and 35.7% of patients with limb-onset ALS and in 37.5%, 25.0%, and 60.0% of patients with bulbar-onset ALS. This simple screen identifies deficits that affect discussions of treatment interventions and end-of-life issues.
Flaherty-Craig
Claire
C
Department of Neurology, Penn State College of Medicine, Penn State Hershey Medical Center, Hershey, PA 17033, USA.
Eslinger
Paul
P
Stephens
Beth
B
Simmons
Zachary
Z
D000328:Adult; D000368:Aged; D000690:Amyotrophic Lateral Sclerosis / Q000503:physiopathology / Q000523:psychology*; D003072:Cognition Disorders / Q000175:diagnosis* / Q000503:physiopathology / Q000523:psychology*; D005625:Frontal Lobe / Q000503:physiopathology; D006801:Humans; D008403:Mass Screening / Q000379:methods*; D008875:Middle Aged; D009483:Neuropsychological Tests