Anticipating instrumentally obtained and passively-received rewards: a factorial fMRI investigation.
During functional magnetic resonance imaging (fMRI), subjects saw cues signaling probabilities of 1.0, 0.5, and 0 of winning $1 for hitting a subsequent target, and cues signaling similar probabilities of reward delivery requiring no instrumental response. Non-instrumental reward anticipation did not elicit activation. Instrumental reward anticipation activated multiple nodes of the basal ganglia-thalamocortical motor circuit. Ventromesial striatum was activated by joint requirement for an instrumental response together with uncertain (but not certain) reward.
Bjork
James M
JM
Laboratory of Clinical and Translational Studies, National Institute on Alcohol Abuse and Alcoholism, NIH, Bethesda, MD 20892, United States. jbjork@mail.nih.gov
Hommer
Daniel W
DW
D000328:Adult; D000704:Analysis of Variance; D001921:Brain / Q000098:blood supply* / Q000502:physiology*; D001931:Brain Mapping; D003213:Conditioning, Psychological / Q000502:physiology*; D005246:Feedback; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods; D016014:Linear Models; D008279:Magnetic Resonance Imaging; D008297:Male; D010100:Oxygen / Q000097:blood; D011336:Probability; D011930:Reaction Time / Q000502:physiology; D012201:Reward; D013997:Time Factors
D010100:Oxygen