Chemiluminescence determination of sodium new houttuyfonate in pharmaceutical preparations based on tween 80-rhodamine B system.
Strong chemiluminescence (CL) emission was observed when sodium new houttuyfonate (SNH) was mixed with Tween 80 in sulfuric acid medium in the presence of rhodamine B. Base on this phenomenon, a sensitive flow injection-CL method for the determination of SNH was developed. Under the optimum conditions, the CL emission is linearly with SNH concentration in the range 8.0-4000 ng mL(-1), with a detection limit of 2.7 ng mL(-1) (3sigma). As a preliminary application, the proposed method was successfully applied to the determination of SNH in pharmaceutical preparations. The possible CL mechanism was also discussed in this paper.
Yang
Xiao-Feng
XF
Department of Chemistry, Northwest University, Xi'an, 710069, P. R. China.
Yao
Hanchun
H
Zhai
Ji-Bao
JB
Li
Hua
H
D000473:Alkanes / Q000032:analysis* / Q000737:chemistry; D005456:Fluorescent Dyes / Q000737:chemistry*; D006863:Hydrogen-Ion Concentration; D008163:Luminescent Measurements; D008823:Micelles; D004364:Pharmaceutical Preparations / Q000032:analysis* / Q000737:chemistry; D011136:Polysorbates / Q000737:chemistry*; D012235:Rhodamines / Q000737:chemistry*; D012680:Sensitivity and Specificity; D013447:Sulfites / Q000032:analysis* / Q000737:chemistry; D013501:Surface-Active Agents / Q000737:chemistry*; D013997:Time Factors
D000473:Alkanes; D005456:Fluorescent Dyes; D008823:Micelles; D004364:Pharmaceutical Preparations; D011136:Polysorbates; D012235:Rhodamines; D013447:Sulfites; D013501:Surface-Active Agents; C473296:sodium houttuyfonate; C029773:rhodamine B