Squamous cell carcinoma with rhabdoid phenotype and osteoclast-like giant cells in a renal-pancreas transplant recipient.
Squamous cell carcinoma (SCC) is the commonest non-melanotic malignant skin tumour encountered after solid-organ transplantation. In this setting it is associated with a worse prognosis than sun-damage-induced SCC. Rhabdoid cells and osteoclastic giant cells are infrequently seen in SCC. This case highlights the unusual occurrence of rhabdoid cells and osteoclastic giant cells in a post-transplant SCC.
Aljerian
K
K
Department of Laboratory Medicine and Pathobiology, University of Toronto, University Health Network, Toronto, Ontario, Canada.
Alsaad
K O
KO
Chetty
R
R
Ghazarian
D
D
D000328:Adult; D002294:Carcinoma, Squamous Cell / Q000209:etiology / Q000473:pathology*; D005153:Facial Neoplasms / Q000209:etiology / Q000473:pathology*; D015726:Giant Cells / Q000473:pathology; D006801:Humans; D016030:Kidney Transplantation / Q000009:adverse effects*; D008297:Male; D010010:Osteoclasts / Q000473:pathology; D016035:Pancreas Transplantation / Q000009:adverse effects*; D012878:Skin Neoplasms / Q000209:etiology / Q000473:pathology*