title: A new stilbene glucoside from the roots of Polygonum multiflorum Thunb.
abstract: One new stilbene glucoside (6), along with five known compounds (1-5), were isolated from the roots of Polygonum multiflorum Thumb., and their chemical structures established based on physicochemical and spectroscopic data. Of the compounds, compound 3 showed DNA topoisomerase I and II inhibitory activities.
authors.affiliation: College of Pharmacy, Yeungnam University, Gyongsan, 712-749, Korea.
authors.forename: Ming-Lu
authors.initials: ML
authors.lastname: Xu
authors.forename: Ming Shan
authors.initials: MS
authors.lastname: Zheng
authors.forename: Yeon-Kyong
authors.initials: YK
authors.lastname: Lee
authors.forename: Dong-Cheol
authors.initials: DC
authors.lastname: Moon
authors.forename: Chong-Soon
authors.initials: CS
authors.lastname: Lee
authors.forename: Mi-Hee
authors.initials: MH
authors.lastname: Woo
authors.forename: Byeong-Seon
authors.initials: BS
authors.lastname: Jeong
authors.forename: Eung Seok
authors.initials: ES
authors.lastname: Lee
authors.forename: Yurngdong
authors.initials: Y
authors.lastname: Jahng
authors.forename: Hyeun-Wook
authors.initials: HW
authors.lastname: Chang
authors.forename: Seung-Ho
authors.initials: SH
authors.lastname: Lee
authors.forename: Jong-Keun
authors.initials: JK
authors.lastname: Son
mesh_terms: D000972:Antineoplastic Agents, Phytogenic / Q000494:pharmacology; D045744:Cell Line, Tumor; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D002855:Chromatography, Thin Layer; D004354:Drug Screening Assays, Antitumor; D004791:Enzyme Inhibitors / Q000494:pharmacology; D005960:Glucosides / Q000737:chemistry / Q000302:isolation & purification; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D008968:Molecular Conformation; D018517:Plant Roots / Q000737:chemistry; D028502:Polygonum / Q000737:chemistry*; D013056:Spectrophotometry, Ultraviolet; D013267:Stilbenes / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D013778:Tetrazolium Salts; D013844:Thiazoles; D059004:Topoisomerase I Inhibitors; D059005:Topoisomerase II Inhibitors
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D004791:Enzyme Inhibitors; D005960:Glucosides; D013267:Stilbenes; D013778:Tetrazolium Salts; D013844:Thiazoles; D059004:Topoisomerase I Inhibitors; D059005:Topoisomerase II Inhibitors; C022616:thiazolyl blue