Treatment of hyperbilirubinemia with blood purification in China.
The incidence of hyperbilirubinemia is high clinically, which is difficult to cure by medication, surgery or interventional therapies. Non-bioartificial liver is the main alternative in the blood purification for hyperbilirubinemia, which includes plasma exchange, hemoperfusion, hemodialysis, molecular adsorbent recycling system and so on. The research results and clinical experiences in China show that these methods are effective in lowering high levels of bilirubin with fewer side effects. The hyperbilirubinemias of different causes, with different complications or accompanying different diseases can be treated by different methods. Bioartificial liver, hybrid artificial liver support system and adsorbent membrane material have also been studied and their development in reducing hyperbilirubinemias has been achieved. This article gives a brief overview on the actuality and research improvement in blood purification for hyperbilirubinemia in China.
Duan
Zhi-Jun
ZJ
Department of Gastroenterology, First Affiliated Hospital of Dalian Medical University, Dalian 116011, Liaoning Province, China. cathydoctor@yahoo.com
Li
Lei-Lei
LL
Ju
Jia
J
Gao
Zhi-Hong
ZH
He
Gao-Hong
GH
D001663:Bilirubin / Q000097:blood / Q000302:isolation & purification; D002681:China; D006464:Hemoperfusion; D006801:Humans; D006932:Hyperbilirubinemia / Q000097:blood / Q000628:therapy*; D019164:Liver, Artificial; D010951:Plasma Exchange; D006435:Renal Dialysis; D016060:Sorption Detoxification / Q000379:methods
D001663:Bilirubin