title: Primary squamous cell carcinoma of the frontal sinus.
abstract: We report a 74-year-old Japanese man with squamous cell carcinoma (SCC) originating in the frontal sinus. It presented as a cutaneous nodule on his right forehead. Magnetic resonance imaging (MRI) revealed invasion of the anterior wall of the ethmoid sinus, the frontal bone, and possibly the meninx by a frontal sinus carcinoma. Despite right fronto craniotomy with en bloc resection followed by two courses of radiation therapy and chemotherapy with 5-fluorouracil and nedaplatin or TS-1 he died of disease-related causes 20 months later. Herein, we present a detailed description of this patient and a review of the published work.
authors.affiliation: Department of Dermatology, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan. non210@m3.kufm.kagoshima-u.ac.jp
authors.forename: Nobuyo
authors.initials: N
authors.lastname: Yoshida
authors.forename: Takuro
authors.initials: T
authors.lastname: Kanekura
authors.forename: Takaki
authors.initials: T
authors.lastname: Hashiguchi
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Nagayama
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Hamada
authors.forename: Tamotsu
authors.initials: T
authors.lastname: Kanzaki
mesh_terms: D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis*; D003937:Diagnosis, Differential; D005005:Ethmoid Sinus / Q000473:pathology; D005153:Facial Neoplasms / Q000175:diagnosis; D017809:Fatal Outcome; D005624:Frontal Bone / Q000473:pathology; D005626:Frontal Sinus / Q000473:pathology*; D006801:Humans; D008297:Male; D009361:Neoplasm Invasiveness; D010255:Paranasal Sinus Neoplasms / Q000175:diagnosis*; D012888:Skull Neoplasms / Q000175:diagnosis