Internucleotide-linkage formation via the phosphoramidite method using a carboxylic acid as a promoter.
This paper describes utility of a carboxylic acid, such as 2,4-dinitrobenzoic acid, as a promoter for internucleotide-linkage formation via the phosphoramidite method.
Tsukamoto
Masaki
M
Graduate School of Information Science, Nagoya University, Chikusa, Nagoya 464-8601, Japan.
Nurminen
Erkki J
EJ
Iwase
Toshihiro
T
Kataoka
Masanori
M
Hayakawa
Yoshihiro
Y
D002264:Carboxylic Acids / Q000737:chemistry*; D002623:Chemistry Techniques, Analytical / Q000379:methods*; D009682:Magnetic Resonance Spectroscopy; D009690:Nucleic Acid Conformation; D009841:Oligonucleotides / Q000138:chemical synthesis / Q000737:chemistry*; D009943:Organophosphorus Compounds / Q000737:chemistry*; D010759:Phosphorus Isotopes
D002264:Carboxylic Acids; D009841:Oligonucleotides; D009943:Organophosphorus Compounds; D010759:Phosphorus Isotopes; C434331:phosphoramidite