title: Carbohydrate antigens: synthesis aspects and immunological applications in cancer.
abstract: Tumor Associated Carbohydrate Antigens (TACAs) constitute powerful tools as tumor markers and as targets for anticancer immunotherapy. In this review, methods of production of glycopeptide-based vaccines, as well as results of preclinical and clinical studies in cancer patients are discussed.
authors.affiliation: CNRS, URA2128, Unité de Chimie Organique, Paris, France. tfreire@pasteur.fr
authors.forename: Teresa
authors.initials: T
authors.lastname: Freire
authors.forename: Sylvie
authors.initials: S
authors.lastname: Bay
authors.forename: Sophie
authors.initials: S
authors.lastname: Vichier-Guerre
authors.forename: Richard
authors.initials: R
authors.lastname: Lo-Man
authors.forename: Claude
authors.initials: C
authors.lastname: Leclerc
mesh_terms: D000951:Antigens, Neoplasm / Q000096:biosynthesis* / Q000276:immunology; D014408:Biomarkers, Tumor / Q000096:biosynthesis* / Q000276:immunology; D006031:Glycosylation; D006801:Humans; D009369:Neoplasms / Q000175:diagnosis / Q000276:immunology*
chemical_list: D000951:Antigens, Neoplasm; D014408:Biomarkers, Tumor