title: [Nonpharmacological diabetes therapy].
abstract: Insulin resistance caused by obesity and lack of physical activity plays a major role for the development of type 2 diabetes. If the reduced insulin action cannot be compensated by overproduction of insulin, glucose regulation disorder is developing. In addition, other trigger factors such as television viewing, sleep, alcohol or smoking are discussed. During the past years an intensification of pharmacological therapy was believed to be the major goal for the treatment of type 2 diabetes, now the value of nonpharmacological treatment improves. While in the past only nutrition was in the view of lifestyle research, recently a number of studies on the value of physical activity were published. In this paper an overview of recent studies showing the therapeutic potential of nonpharmacological therapies will be given. It will also be shown that these measures will not only optimize hyperglycaemia but also all other cardiovascular risk factors.
authors.affiliation: Deutsche Diabetes-Klinik, Deutsches Diabetes-Zentrum, Leibniz-Zentrum für Diabetes-Forschung an der Heinrich-Heine-Universität Düsseldorf, Düsseldorf, Deutschland. martin@ddz.uni-duesseldorf.de
authors.forename: Stephan
authors.initials: S
authors.lastname: Martin
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000428:Alcohol Drinking / Q000009:adverse effects; D015992:Body Mass Index; D003069:Coffee; D018592:Cross-Over Studies; D003924:Diabetes Mellitus, Type 2 / Q000097:blood / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology / Q000517:prevention & control / Q000628:therapy*; D015444:Exercise; D005260:Female; D005500:Follow-Up Studies; D005951:Glucose Tolerance Test; D006801:Humans; D015994:Incidence; D007333:Insulin Resistance; D008019:Life Style; D008875:Middle Aged; D009765:Obesity / Q000150:complications; D011236:Prediabetic State / Q000175:diagnosis / Q000517:prevention & control; D011446:Prospective Studies; D016032:Randomized Controlled Trials as Topic; D012307:Risk Factors; D012737:Sex Factors; D012893:Sleep Wake Disorders / Q000150:complications; D012907:Smoking / Q000009:adverse effects; D013690:Television; D013997:Time Factors; D016138:Walking
chemical_list: D003069:Coffee