[A case of rheumatoid lung complicated by SELAPINA-induced pneumonia].
SELAPINA is generic product of PL granule which is one of the most common forms of combination remedies for the common cold in Japan, and includes acetaminophen. We report a case of SELAPINA-induced pneumonia successfully treated with glucocorticoid pulse therapy followed by orally administered prednisolone. A 68-year-old woman, who had been treated for rheumatoid arthiritis with pulmonary involvement, took SELAPINA with an antibiotic for 6 days because of her cold symptoms. She then suffered a high fever, cough, dyspnea, vomiting and diarrhea. Chest radiograph and high-resolution computed tomography (HRCT) scan revealed diffuse interstitial shadows. SELAPINA-induced pneumonia was diagnosed because the blastoid transformation test using her peripheral blood lymphocytes was positive on stimulation with SELAPINA, but negative for other medicines.
Nakayama
Seiko
S
Second Department of Internal Medicine, Nagasaki University School of Medicine.
Mukae
Hiroshi
H
Ishimatsu
Yuji
Y
Sugiyama
Kanako
K
Ide
Mioko
M
Ishimoto
Hiroshi
H
Hisatomi
Keiko
K
Ishii
Hiroshi
H
Abel
Koh
K
Ozono
Yoshiyuki
Y
Kohno
Shigeru
S
D000082:Acetaminophen / Q000009:adverse effects*; D000368:Aged; D000638:Amiodarone / Q000009:adverse effects*; D001172:Arthritis, Rheumatoid / Q000150:complications / Q000188:drug therapy; D004338:Drug Combinations; D005260:Female; D006801:Humans; D008171:Lung Diseases / Q000150:complications*; D011014:Pneumonia / Q000139:chemically induced*; D012216:Rheumatic Diseases / Q000150:complications*
D004338:Drug Combinations; C517665:SELAPINA; D000082:Acetaminophen; D000638:Amiodarone