[Helicobacter pylori infection and its correlation with gastrointestinal symptoms and outcome of pregnancy].
OBJECTIVE
The present study intended to investigate whether there was a relationship between pregnant women with dyspeptic complaints and with and without Helicobacter pylori infection in the first and second trimester of pregnancy.


METHODS
H.pylori seropositivity was determined in 146 (aged 20 to 40 years) antenatal patients at 10 to 23 weeks gestation. H.Pylori ser um Immunoglobulin IgG antibody concentrations were determined by enzyme-linked immunoadsorbent assay (ELISA). Age, obesity, parity, outcome of pregnancy and dyspeptic symptoms were registered in the patients' medical records. Chi-square and Student's t-test were used for statistical analysis of the data.


RESULTS
Prevalence of H.pylori infection in the population studied was 65.7% (96 of 146). H pylori infection was not associated with parity, preterm delivery, obesity or with dyspeptic symptoms. Women positive for H.pylori IgG were older (30, 45 +/- 6.87 vs 27, 96 +/- 7.44, p= 0.045565*) than H. pylori negative patients.


CONCLUSIONS
In this study there was no association of H pylori infection with dyspeptic symptoms in pregnancy, nor was its presence associated with obesity, parity and outcome of pregnancy.
Bromberg
Sansom Henrique
SH
Serviço de Obstetrícia e Ginecologia do Hospital do Servidor Público Estadual--Francisco Morato de Oliveira (HSPE-FMO). brombengsh@yahoo.com.br
Takei
Kioko
K
Garcia
Sidney Antonio Lagrosa
SA
Vitor
André da Costa
Ada C
Zanoto
Arnaldo
A
Baracat
Fausto Farah
FF
D000293:Adolescent; D000328:Adult; D000907:Antibodies, Bacterial / Q000097:blood; D015992:Body Mass Index; D001938:Brazil / Q000453:epidemiology; D004415:Dyspepsia / Q000097:blood / Q000453:epidemiology / Q000382:microbiology*; D004797:Enzyme-Linked Immunosorbent Assay; D004812:Epidemiologic Methods; D005260:Female; D016481:Helicobacter Infections / Q000097:blood / Q000150:complications* / Q000453:epidemiology; D016480:Helicobacter pylori / Q000276:immunology; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D008875:Middle Aged; D010298:Parity; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000097:blood / Q000453:epidemiology / Q000382:microbiology*; D011256:Pregnancy Outcome; D011261:Pregnancy Trimester, First
D000907:Antibodies, Bacterial; D007074:Immunoglobulin G