title: [Diagnosis and treatment of laryngopharyngeal reflux].
abstract: BACKGROUND
  During the last decades an increased prevalence of reflux disease can be observed. Otolaryngologists play an increasing role in the treatment of patients suffering from laryngopharyngeal reflux (LPR). Typical symptoms for LPR are globus sensation, dysphagia, throat clearing, chronic cough and hoarseness. The most frequent laryngoscopic finding in patients suffering from LPR is a posterior commissure hypertrophy. LPR is confirmed by laryngoscopy, LPR-related laryngoscopy scoring, 24-hour dual-probe pH-monitoring, and by empiric trial with proton pump inhibitors (PPI). For therapy PPI-medication in a dosage of 40 mg BID for at least 3 months is successful in many patients. Additional lifestyle modifications can also have a positive effect. When medical management fails, further diagnostic procedures should be initiated.
  
  
  CONCLUSIONS
  In patients suffering from unspecific laryngeal and respiratory symptoms LPR is an important differential diagnosis.
authors.affiliation: Klinik für Hals-Nasen-Ohrenheilkunde, Ludwig-Maximilians-Universität, München. Oliver.Reichel@med.uni-muenchen.de
authors.forename: O
authors.initials: O
authors.lastname: Reichel
authors.forename: H
authors.initials: H
authors.lastname: Hagedorn
authors.forename: A
authors.initials: A
authors.lastname: Berghaus
mesh_terms: D000328:Adult; D002908:Chronic Disease; D003371:Cough / Q000209:etiology; D003680:Deglutition Disorders / Q000209:etiology; D003937:Diagnosis, Differential; D050782:Esophageal pH Monitoring; D005260:Female; D018662:Fundoplication; D005764:Gastroesophageal Reflux / Q000175:diagnosis; D006685:Hoarseness / Q000209:etiology; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007013:Hypopharynx; D007818:Laryngeal Diseases / Q000175:diagnosis; D007828:Laryngoscopy; D008019:Life Style; D008297:Male; D008875:Middle Aged; D010608:Pharyngeal Diseases / Q000175:diagnosis / Q000628:therapy; D054328:Proton Pump Inhibitors; D011795:Surveys and Questionnaires; D013997:Time Factors
chemical_list: D054328:Proton Pump Inhibitors