title: Effects of various cations on the dynamic and thermodynamics of the dimerization of G-quadruplex DNA.
abstract: DNA fragment, d(TTAGGG), forms all-parallel G-quadruplex in the presence of K(+).(1) We found that G-quadruplex d(TTAGGG) dimerizes through end-to-end stacking of the 3'-terminal G-quartets.(2) In this study, we report the effects of Mg(2+) and Ca(2+) on the dynamics and thermodynamics of the dimerization.
authors.affiliation: Department of Chemistry, University of Tsukuba, Tsukuba 305-8571, Japan.
authors.forename: Hajime
authors.initials: H
authors.lastname: Mita
authors.forename: Yoshitake
authors.initials: Y
authors.lastname: Kato
authors.forename: Makie
authors.initials: M
authors.lastname: Ozawa
authors.forename: Toshinori
authors.initials: T
authors.lastname: Fujisaki
authors.forename: Yasuhiko
authors.initials: Y
authors.lastname: Yamamoto
mesh_terms: D002118:Calcium / Q000737:chemistry*; D002413:Cations, Divalent / Q000737:chemistry; D004247:DNA / Q000737:chemistry*; D019281:Dimerization; D054856:G-Quadruplexes; D006801:Humans; D008274:Magnesium / Q000737:chemistry*; D019906:Nuclear Magnetic Resonance, Biomolecular; D016615:Telomere / Q000737:chemistry; D013816:Thermodynamics
chemical_list: D002413:Cations, Divalent; D004247:DNA; D008274:Magnesium; D002118:Calcium