[A case of Churg-Strauss syndrome discovered with hematemesis].
A 68-years-old Japanese woman was hospitalized emergently because of hemorrhagic gastric ulcer. For the hospitalization period, elevated levels of white blood cell count, eosinophilic leucocyte count, serum IgE and positive MPO-ANCA were recognized. With considering clinical course and these laboratory findings, we diagnosed Churg-Strauss syndrome (CSS). Steroid therapy in combination with cyclophosphamide was effective. CSS is a rare disease, but we should discriminate this disease when we encounter gastrointestinal bleeding of unknown etiology, especially PPI-resistant gastric ulcer.
Okudaira
Keisuke
K
Second Department of Internal Medicine, National Defense Medical College.
Kawaguchi
Atsushi
A
Hokari
Ryota
R
Narimatsu
Kazuyuki
K
Higashiyama
Masaaki
M
Mataki
Norikazu
N
Kato
Shingo
S
Komoto
Syunsuke
S
Tsuzuki
Yoshikazu
Y
Nagao
Shigeaki
S
Itoh
Kazuro
K
Miura
Soichiro
S
D000368:Aged; D015267:Churg-Strauss Syndrome / Q000175:diagnosis* / Q000188:drug therapy; D003520:Cyclophosphamide / Q000008:administration & dosage; D004359:Drug Therapy, Combination; D005260:Female; D006396:Hematemesis / Q000209:etiology*; D006801:Humans; D008775:Methylprednisolone / Q000008:administration & dosage; D010438:Peptic Ulcer Hemorrhage / Q000150:complications*; D020551:Pulse Therapy, Drug; D013276:Stomach Ulcer / Q000150:complications*
D003520:Cyclophosphamide; D008775:Methylprednisolone