Metabolic alkalosis in a hemodialysis patient--successful treatment with a proton pump inhibitor.
Hemodialysis patients develop metabolic acidosis due to their impaired excretion of daily produced protons (H+). The following report will show a rare case of severe metabolic alkalosis (predialysis pH 7.52, base excess (BE) +17) in a hemodialysis woman caused by self-provoked upper gastrointestinal H+ losses based on an eating disorder. Treatment with a proton pump inhibitor resulted in the normalization of acid/base homeostasis (predialysis pH 7.40, BE +1.6).
Kirsch
B M
BM
Division of Nephrology and Dialysis, Department of Medicine Ill, Medical University of Vienna, Austria. bernhard.kirsch@meduniwien.ac.at
Sunder-Plassmann
G
G
Schwarz
C
C
D053799:2-Pyridinylmethylsulfinylbenzimidazoles / Q000627:therapeutic use*; D000471:Alkalosis / Q000188:drug therapy* / Q000209:etiology*; D000897:Anti-Ulcer Agents / Q000627:therapeutic use*; D001068:Feeding and Eating Disorders / Q000150:complications*; D005260:Female; D006801:Humans; D006863:Hydrogen-Ion Concentration; D052177:Kidney Diseases, Cystic / Q000628:therapy*; D008875:Middle Aged; D000077402:Pantoprazole; D006435:Renal Dialysis / Q000009:adverse effects*
D053799:2-Pyridinylmethylsulfinylbenzimidazoles; D000897:Anti-Ulcer Agents; D000077402:Pantoprazole