Genetic differences by platelet-specific antigens used for monitoring allomyelotransplant engraftment.
Monitoring of allomyelotransplant engraftment is essential for evaluation of the function of transplanted cells and timely diagnosis of disease relapse. The possibility of using differences by HPA genes for monitoring of survival of transplanted hemopoietic stem cells was studied. Differences by HPA genes in HLA-identical sibs can be used for the analysis of chimerism after myelotransplantation.
Golovkina
L L
LL
Hematology Research Center, Russian Academy of Medical Sciences, Moscow. largol@aport.ru
Kutyina
R M
RM
Savchenko
V G
VG
D000483:Alleles; D016824:Antigens, Human Platelet / Q000235:genetics*; D017690:Cell Transplantation; D046528:Chimerism; D005192:Family Health; D005260:Female; D005838:Genotype; D006680:HLA Antigens; D018380:Hematopoietic Stem Cell Transplantation / Q000379:methods*; D006801:Humans; D016130:Immunophenotyping; D008297:Male; D016133:Polymerase Chain Reaction; D012008:Recurrence; D014184:Transplantation, Homologous / Q000379:methods*
D016824:Antigens, Human Platelet; D006680:HLA Antigens