title: Ventral and dorsal root injury after oxygen-ozone therapy for lumbar disk herniation.
abstract: BACKGROUND
  O2O3 therapy has become a largely diffused treatment for lumbar disk herniation; this procedure is considered generally risk-free.
  
  
  METHODS
  We report a case of ventral and dorsal root injury occurring after transcutaneous intradiscal infiltration of O2O3 for L4-L5 disk herniation.
  
  
  CONCLUSIONS
  Until randomized controlled trials on efficacy and short-term safety have been carried out, we think that physicians should be informed about the risk of potential complications when recommending this procedure.
authors.affiliation: Department of Neurological and Behavioral Sciences, Unit of Clinical Neurophysiology, University of Siena, 53100 Siena, Italy. ginanneschi@unisi.it
authors.forename: Federica
authors.initials: F
authors.lastname: Ginanneschi
authors.forename: Carlo
authors.initials: C
authors.lastname: Cervelli
authors.forename: Paolo
authors.initials: P
authors.lastname: Milani
authors.forename: Alessandro
authors.initials: A
authors.lastname: Rossi
mesh_terms: D005260:Female; D006801:Humans; D007278:Injections, Spinal / Q000009:adverse effects; D007405:Intervertebral Disc Displacement / Q000473:pathology / Q000628:therapy*; D008159:Lumbar Vertebrae / Q000294:innervation / Q000473:pathology; D009682:Magnetic Resonance Spectroscopy; D008875:Middle Aged; D010100:Oxygen / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D010126:Ozone / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D013126:Spinal Nerve Roots / Q000187:drug effects / Q000293:injuries*
chemical_list: D010126:Ozone; D010100:Oxygen