title: Signal transduction mechanisms in memory disorders.
abstract: This chapter explores some of the molecular events contributing to memory formation and how, when these events malfunction, disturbances in memory occur. After a brief discussion of signaling in the hippocampus, we will explore the topics of human mental retardation syndromes that involve disruption of these processes, including Angelman syndrome (AS), Neurofibromatosis 1 (NF1)-associated learning disorders, Coffin-Lowry syndrome (CLS), Rubinstein-Taybi syndrome (RTS), and Rett syndrome (RTT).
authors.affiliation: Department of Neuroscience, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA.
authors.forename: Sara C
authors.initials: SC
authors.lastname: Shalin
authors.forename: Regula
authors.initials: R
authors.lastname: Egli
authors.forename: Shari G
authors.initials: SG
authors.lastname: Birnbaum
authors.forename: Tania L
authors.initials: TL
authors.lastname: Roth
authors.forename: Johathan M
authors.initials: JM
authors.lastname: Levenson
authors.forename: J David
authors.initials: JD
authors.lastname: Sweatt
mesh_terms: D000818:Animals; D006624:Hippocampus / Q000503:physiopathology; D006801:Humans; D008607:Intellectual Disability / Q000503:physiopathology; D008569:Memory Disorders / Q000503:physiopathology*; D015398:Signal Transduction / Q000502:physiology*