title: [Production of granulocyte colony-stimulating factor and parathyroid hormone-related protein in squamous cell carcinoma of the renal pelvis accompanied with inferior vena cava thrombus].
abstract: A 54-year-old man with general fatigue and lumbago was admitted for further examination of hypercalcemia and leukocytosis. CT showed a huge renal tumor and extension of the tumor thrombus to the inferior vena cava (IVC). Moreover, the serum granulocyte colony-stimulating factor (G-CSF) and the C-terminal of parathyroid hormone-related protein (PTHrP) were elevated. Under the diagnosis of advanced renal tumor, we performed nephro-ureterectomy and throbectomy. Pathological examination revealed squamous cell carcinoma of the renal pelvis. To our knowledge, this is the first case in Japan that of the simultaneous production of G-CSF and PTHrP in squamous cell carcinoma of the renal pelvis accompanied with IVC thrombus.
authors.affiliation: Department of Urology, Kitamurayama Public Hospital.
authors.forename: Kaoru
authors.initials: K
authors.lastname: Nemoto
authors.forename: Ichiro
authors.initials: I
authors.lastname: Matsuzawa
authors.forename: Go
authors.initials: G
authors.lastname: Kimura
authors.forename: Taiji
authors.initials: T
authors.lastname: Nishimura
mesh_terms: D002294:Carcinoma, Squamous Cell / Q000150:complications / Q000378:metabolism* / Q000601:surgery; D016179:Granulocyte Colony-Stimulating Factor / Q000096:biosynthesis*; D006801:Humans; D007680:Kidney Neoplasms / Q000150:complications / Q000378:metabolism* / Q000601:surgery; D007682:Kidney Pelvis; D008297:Male; D008875:Middle Aged; D009392:Nephrectomy; D010257:Paraneoplastic Syndromes; D044162:Parathyroid Hormone-Related Protein / Q000096:biosynthesis*; D017131:Thrombectomy; D013927:Thrombosis / Q000150:complications / Q000601:surgery*; D014682:Vena Cava, Inferior
chemical_list: D044162:Parathyroid Hormone-Related Protein; D016179:Granulocyte Colony-Stimulating Factor