Influence of the concentrations of liposomes and a submicron emulsion on the rheological properties of a topical gel.
Two different kinds of liposomes and a submicron emulsion were added to a topical hydrogel consisting of alginates. The rheological characteristics of the gels after various dilutions were investigated. The various preparations studied exhibited a similar rheological behaviour. No important interactions were observed by mixing the hydrogel with liposomes or a submicron emulsion. The viscoelastic properties and gel state were preserved, only a decrease in consistency was measured.
Weyenberg
W
W
Laboratory of Pharmaceutical Technology and Biopharmacy, Department of Pharmaceutical Sciences, University of Antwerp, Belgium.
Sollie
P
P
Ludwig
A
A
D000287:Administration, Topical; D000465:Algorithms; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D004655:Emulsions / Q000737:chemistry*; D005079:Excipients; D005782:Gels; D008081:Liposomes / Q000737:chemistry*; D010316:Particle Size; D010713:Phosphatidylcholines; D010743:Phospholipids; D012212:Rheology
D004655:Emulsions; D005079:Excipients; D005782:Gels; D008081:Liposomes; D010713:Phosphatidylcholines; D010743:Phospholipids