title: An in vitro study on the effect of TiF(4) treatment against erosion by hydrochloric acid on pellicle-covered enamel.
abstract: The aim of this in vitro study was to examine the effect of fluoride treatment on pellicle-covered enamel exposed to an acidic challenge simulating gastric reflux. Sixteen bovine and 16 human teeth were sectioned into four pieces, divided into four groups: (1) control, (2) 2-hour pellicle, (3) TiF(4), and (4) 2-hour pellicle + TiF(4), and subsequently subjected to 3 ml 0.01 M HCl stepwise for 4 + 4 + 4 min. The acid was analysed for calcium by atomic absorption spectroscopy. TiF(4) reduced Ca release from enamel by 76, 57 and 56% following the 4 + 4 + 4-min acid exposures, respectively, in bovine and 44, 54 and 54% in human enamel. These results suggest that treatment of enamel with a TiF(4) solution, with or without pellicle removal, may provide protection for the enamel against acid attack.
authors.affiliation: Faculty of Dentistry, University of Oslo, Oslo, Norway. lenehh@odont.uio.no
authors.forename: L H
authors.initials: LH
authors.lastname: Hove
authors.forename: A
authors.initials: A
authors.lastname: Young
authors.forename: A B
authors.initials: AB
authors.lastname: Tveit
mesh_terms: D000818:Animals; D002118:Calcium / Q000032:analysis; D002327:Cariostatic Agents / Q000494:pharmacology* / Q000627:therapeutic use; D002417:Cattle; D044622:Dental Pellicle / Q000187:drug effects* / Q000502:physiology; D006801:Humans; D006851:Hydrochloric Acid / Q000009:adverse effects*; D014002:Tin Fluorides / Q000494:pharmacology* / Q000627:therapeutic use; D014077:Tooth Erosion / Q000139:chemically induced / Q000517:prevention & control*
chemical_list: D002327:Cariostatic Agents; D014002:Tin Fluorides; D006851:Hydrochloric Acid; D002118:Calcium