Concomitant disseminated histoplasmosis and cryptococcosis in a person with AIDS.
A 46-year-old Hispanic male from Ecuador presented with fever, malaise, weight loss, and dyspnea. He was HIV-positive with a CD4+ cell count of 4/microL. He was hospitalized, and therapy for community-acquired pneumonia with broad-spectrum antibiotics was started. Both Histoplasma capsulatum and Cryptococcus neoformans were cultured from bronchial lavage, blood, and bone marrow specimens. Despite aggressive therapy with amphotericin B, the patient died 8 days after admission.
Swaminathan
Shobha
S
Division of Infectious Diseases, Department of Medicine, University of Medicine and Dentistry of New Jersey, New Jersey Medical School, Newark, USA.
Imrit
Kavita
K
Green
Jamie
J
Das
Kasturi
K
D017088:AIDS-Related Opportunistic Infections / Q000382:microbiology*; D000163:Acquired Immunodeficiency Syndrome / Q000382:microbiology*; D003453:Cryptococcosis / Q000821:virology*; D003455:Cryptococcus neoformans / Q000302:isolation & purification; D006678:HIV; D006658:Histoplasma / Q000302:isolation & purification; D006660:Histoplasmosis / Q000821:virology*; D006801:Humans; D008297:Male; D008875:Middle Aged