title: Influence of fluoride dentifrice on brushing abrasion of eroded human enamel: an in situ/ex vivo study.
abstract: This in situ/ex vivo study assessed the effect of fluoride dentifrice on eroded enamel subjected to brushing abrasion. In a crossover study performed in 2 phases, 10 volunteers wore acrylic palatal appliances, each containing 3 human enamel blocks. Dentifrice was used to brush the volunteers' teeth and the specimens subjected to abrasion. In phases A and B the dentifrices used had the same formulation, except for the absence or presence of fluoride, respectively. The blocks were subjected to erosion by immersion of the appliances in a cola drink for 5 min, 4 times a day. Then the blocks were brushed, and the appliance was replaced into the mouth. Enamel alterations were determined using profilometry and percentage change in surface microhardness (%SMHC) tests. The data were tested using the paired t test. The mean wear values (+/-SD, microm) were: group A 6.84 +/- 1.72 and group B 5.38 +/- 1.21 (p = 0.04). The mean %SMHC values (+/-SD) were: group A 54.6 +/- 16.2 and group B 45.7 +/- 6.8 (p = 0.04). Fluoride dentifrice had a protective effect on eroded enamel subjected to brushing abrasion.
authors.affiliation: Bauru School of Dentistry, University of São Paulo, Bauru, Brazil.
authors.forename: A C
authors.initials: AC
authors.lastname: Magalhães
authors.forename: D
authors.initials: D
authors.lastname: Rios
authors.forename: A C B
authors.initials: AC
authors.lastname: Delbem
authors.forename: M A R
authors.initials: MA
authors.lastname: Buzalaf
authors.forename: M A A M
authors.initials: MA
authors.lastname: Machado
mesh_terms: D000328:Adult; D000704:Analysis of Variance; D003743:Dental Enamel / Q000737:chemistry / Q000187:drug effects*; D003802:Dentifrices / Q000009:adverse effects* / Q000737:chemistry; D004311:Double-Blind Method; D005459:Fluorides / Q000494:pharmacology*; D006244:Hardness / Q000187:drug effects; D006801:Humans; D013499:Surface Properties; D014072:Tooth Abrasion / Q000188:drug therapy* / Q000517:prevention & control; D014077:Tooth Erosion / Q000139:chemically induced / Q000188:drug therapy
chemical_list: D003802:Dentifrices; D005459:Fluorides