[Multifocal visual evoked potential in retinitis pigmentosa and its comparison with visual field].
OBJECTIVE
To investigate the characteristics of the multifocal visual evoked potential (mfVEP) and to evaluate the potential of mfVEP as a way of objective perimetry in retinitis pigmentosa (RP).


METHODS
The mfVEPs were obtained by using VERIS 4.9 visual evoked response imaging system for 12 RP patients (19 eyes) and 15 normal control subjects (30 eyes). The stimulative field consisted of 60 sectors in a dartboard configuration, the visual angle of one side was 26 degrees. The amplitude sums of P1 wave of the first slice of the second order kernel from patients with RP were compared with values from control subjects. The central 30 degrees visual fields were obtained in the RP patients. Correlation between sensitivity sums of visual field and amplitude sums of P1 wave was performed in the same area.


RESULTS
The amplitude sums of P1 wave decreased significantly at all rings in RP group compared with those of normal control group (P < 0.05). Except for inferior ring 1 and inferior ring 2, there was correlation between sensitivity sums of visual field and amplitude sums of P1 wave at the other rings (P < 0.05).


CONCLUSIONS
There was a certain correlation between visual field and mfVEP. The mfVEP can be a method to evaluate visual function objectively in RP.
Long
Shixian
S
Key Laboratory of Ophthalmology of Ministry of Education and Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510060, China.
Jiang
Futian
F
Wu
Dezheng
D
Liang
Jiongji
J
D000328:Adult; D002648:Child; D005074:Evoked Potentials, Visual; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012174:Retinitis Pigmentosa / Q000175:diagnosis* / Q000473:pathology / Q000503:physiopathology; D058609:Visual Field Tests; D014794:Visual Fields