Homing in on bile acid physiology.
Fibroblast growth factor 15 (Fgf15), a hormone made by the terminal ileum in response to bile acids, represses hepatic bile acid biosynthesis. demonstrate that Fgf15 is also required for gallbladder filling.
Houten
Sander M
SM
Department of Clinical Chemistry, Laboratory Genetic Metabolic Diseases, Emma Children's Hospital, Academic Medical Center, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands.
D000818:Animals; D001647:Bile Acids and Salts / Q000096:biosynthesis*; D005346:Fibroblast Growth Factors / Q000378:metabolism*; D005704:Gallbladder / Q000502:physiology*; D006801:Humans; D007082:Ileum / Q000502:physiology*; D051379:Mice
D001647:Bile Acids and Salts; C108526:fibroblast growth factor 15, mouse; D005346:Fibroblast Growth Factors