GNOSIS: guidelines for neuro-oncology: standards for investigational studies--reporting of surgically based therapeutic clinical trials.
We present guidelines to standardize the reporting of surgically based neuro-oncology trials. The guidelines are summarized in a checklist format that can be used as a framework from which to construct a surgically based trial. This manuscript follows and is taken in part from GNOSIS: Guidelines for neuro-oncology: Standards for investigational studies-reporting of phase 1 and phase 2 clinical trials [Chang SM, Reynolds SL, Butowski N, Lamborn KR, Buckner JC, Kaplan RS, Bigner DD (2005) Neuro-oncology 7:425-434].
Chang
Susan
S
Neuro-oncology Service, Department of Neurological Surgery, University of California San Francisco, 400 Parnassus Avenue, A-808, San Francisco, CA 94143-0350, USA. changs@neurosurg.ucsf.edu
Vogelbaum
Michael
M
Lang
Frederick F
FF
Haines
Stephen
S
Kunwar
Sandeep
S
Chiocca
E Antonio
EA
Olivi
Alessandro
A
Quinones-Hinojosa
Alfredo
A
Parsa
Andrew
A
Warnick
Ronald
R
D002986:Clinical Trials as Topic / Q000592:standards*; D003627:Data Interpretation, Statistical; D006801:Humans; D009423:Nervous System Neoplasms / Q000628:therapy*; D012107:Research Design / Q000592:standards*