title: Current experience with percutaneous pulmonary valve implantation.
abstract: Transcatheter valve replacement has recently been introduced into clinical practice and has the potential to transform the management of valvular heart disease. To date, the largest human experience exists with percutaneous pulmonary valve implantation in patients with repaired congenital heart disease who require re-intervention to the right ventricular outflow tract. The application of this approach, however, is presently restricted to certain right ventricular outflow tract morphologies, because the device needs to be anchored safely to prevent device dislodgement. Early results of percutaneous pulmonary valve implantation show lower morbidity than surgery and significant early symptomatic improvement. In the future, the challenge will be to extend percutaneous pulmonary valve implantation to all patients with a clinical indication to delay or avoid repeat open-heart surgery.
authors.affiliation: The Cardiac Unit, Institute of Child Health and Great Ormond Street Hospital for Children, London, United Kingdom. NordmJ@gosh.nhs.uk
authors.forename: Johannes
authors.initials: J
authors.lastname: Nordmeyer
authors.forename: Louise
authors.initials: L
authors.lastname: Coats
authors.forename: Philipp
authors.initials: P
authors.lastname: Bonhoeffer
mesh_terms: D017023:Coronary Angiography; D006350:Heart Valve Prosthesis; D019918:Heart Valve Prosthesis Implantation / Q000009:adverse effects; D006801:Humans; D007902:Length of Stay; D011474:Prosthesis Design; D011664:Pulmonary Valve / Q000601:surgery*; D011665:Pulmonary Valve Insufficiency / Q000601:surgery*; D015607:Stents