title: Effects of a physical activity intervention on measures of physical performance: Results of the lifestyle interventions and independence for Elders Pilot (LIFE-P) study.
abstract: BACKGROUND
  The Short Physical Performance Battery (SPPB), which includes walking, balance, and chair stands tests, independently predicts mobility disability and activities of daily living disability. To date, however, there is no definitive evidence from randomized controlled trials that SPPB scores can be improved. Our objective was to assess the effect of a comprehensive physical activity (PA) intervention on the SPPB and other physical performance measures.
  
  
  METHODS
  A total of 424 sedentary persons at risk for disability (ages 70-89 years) were randomized to a moderate-intensity PA intervention or a successful aging (SA) health education intervention and were followed for an average of 1.2 years.
  
  
  RESULTS
  The mean baseline SPPB score on a scale of 0-12, with 12 corresponding to highest performance, was 7.5. At 6 and 12 months, the PA versus SA group adjusted SPPB (+/- standard error) scores were 8.7 +/- 0.1 versus 8.0 +/- 0.1, and 8.5 +/- 0.1 versus 7.9 +/- 0.2, respectively (p < .001). The 400-meter walking speed was also significantly improved in the PA group. The PA group had a lower incidence of major mobility disability defined as incapacity to complete a 400-meter walk (hazard ratio = 0.71, 95% confidence interval = 0.44-1.20).
  
  
  CONCLUSIONS
  A structured PA intervention improved the SPPB score and other measures of physical performance. An intervention that improves the SPPB performance may also offer benefit on more distal health outcomes, such as mobility disability.
authors.affiliation: Department of Aging and Geriatric Research, College of Medicine, University of Florida, 1329 SW 16th St., Rm. 5161, Gainesville, FL 32608, USA. mpahor@ufl.edu
authors.forename: Marco
authors.initials: M
authors.lastname: Pahor
authors.forename: Steven N
authors.initials: SN
authors.lastname: Blair
authors.forename: Mark
authors.initials: M
authors.lastname: Espeland
authors.forename: Roger
authors.initials: R
authors.lastname: Fielding
authors.forename: Thomas M
authors.initials: TM
authors.lastname: Gill
authors.forename: Jack M
authors.initials: JM
authors.lastname: Guralnik
authors.forename: Evan C
authors.initials: EC
authors.lastname: Hadley
authors.forename: Abby C
authors.initials: AC
authors.lastname: King
authors.forename: Stephen B
authors.initials: SB
authors.lastname: Kritchevsky
authors.forename: Cinzia
authors.initials: C
authors.lastname: Maraldi
authors.forename: Michael E
authors.initials: ME
authors.lastname: Miller
authors.forename: Anne B
authors.initials: AB
authors.lastname: Newman
authors.forename: Walter J
authors.initials: WJ
authors.lastname: Rejeski
authors.forename: Sergei
authors.initials: S
authors.lastname: Romashkan
authors.forename: Stephanie
authors.initials: S
authors.lastname: Studenski
mesh_terms: D000203:Activities of Daily Living; D000368:Aged; D000369:Aged, 80 and over; D004185:Disability Evaluation; D015444:Exercise; D005260:Female; D005500:Follow-Up Studies; D015577:Geriatric Assessment; D015438:Health Behavior; D006266:Health Education; D006293:Health Promotion; D006801:Humans; D008019:Life Style; D008297:Male; D010865:Pilot Projects; D016037:Single-Blind Method; D016138:Walking