title: A fiber optic sensor system for control of rate-adaptive cardiac pacemakers and implantable defibrillators.
abstract: Commercially available cardiac pacemakers and implantable cardioverters/defibrillators (ICDs) predominantly use an intracardiac-derived electrocardiogram (ECG) for the detection of arrhythmias. To achieve automatic control of the heart frequency in accordance with cardiovascular strain and improved detection of life-threatening arrhythmias, it is desirable to monitor the heart by an input signal correlated with the hemodynamic state. One possible approach to derive such a signal is to measure the inotropy (mechanical contraction strength of the heart muscle). For this purpose, an optoelectronic measurement system has been designed. The fundamental function of the system has been shown in earlier investigations using an isolated beating pig heart. In this paper the design of two algorithms for use in pacemakers and ICDs based on a fiber optic sensor signal is presented.
authors.affiliation: Department of Biomedical Engineering, Medical Faculty and University Center of Medical Engineering (UZMT), Ruhr University, Bochum, Germany.
authors.forename: Stefan
authors.initials: S
authors.lastname: Müller
authors.forename: Martin
authors.initials: M
authors.lastname: Hexamer
authors.forename: Jürgen
authors.initials: J
authors.lastname: Werner
mesh_terms: D000465:Algorithms; D000818:Animals; D017147:Defibrillators, Implantable; D004867:Equipment Design; D019544:Equipment Failure Analysis; D005336:Fiber Optic Technology / Q000295:instrumentation*; D066298:In Vitro Techniques; D008365:Manometry / Q000295:instrumentation* / Q000379:methods; D009200:Myocardial Contraction / Q000502:physiology; D055100:Optical Fibers; D010138:Pacemaker, Artificial; D013552:Swine; D013813:Therapy, Computer-Assisted / Q000295:instrumentation / Q000379:methods*; D014159:Transducers; D016277:Ventricular Function, Left / Q000502:physiology*