title: [The antithrombotic-treated patient].
abstract: Management of perioperative treatment with anticoagulants and antiplatelet drugs is a complex medical problem. Careful preoperative evaluation of the risk of bleeding and thromboembolism with and without of antithrombotic therapy is the key prerequisite to secure safe outcome of elective, invasive procedures performed on patients treated with antithrombotic agents. In emergency cases, knowledge of the pharmacokinetics and pharmacodynamics of antithrombotic drugs and of the effect of antidotes and blood-derived, recombinant, and other haemostatic products is important.
authors.affiliation: Amtssygehuset i Gentofte, Trombosecentret, Klinisk-biokemisk Afdeling, H:S Bispebjerg Hospital, Hellerup. jdn@dadlnet.dk
authors.forename: Jørn Dalsgaard
authors.initials: JD
authors.lastname: Nielsen
authors.forename: Hans Morten Schnack
authors.initials: HM
authors.lastname: Rasmussen
authors.forename: Steen Elkjaer
authors.initials: SE
authors.lastname: Husted
mesh_terms: D000925:Anticoagulants / Q000008:administration & dosage / Q000009:adverse effects* / Q000493:pharmacokinetics; D017558:Elective Surgical Procedures / Q000009:adverse effects; D004630:Emergencies; D005343:Fibrinolytic Agents / Q000008:administration & dosage / Q000009:adverse effects* / Q000493:pharmacokinetics; D006470:Hemorrhage / Q000139:chemically induced* / Q000517:prevention & control; D006490:Hemostatics / Q000008:administration & dosage; D006801:Humans; D007431:Intraoperative Complications / Q000139:chemically induced* / Q000517:prevention & control; D010975:Platelet Aggregation Inhibitors / Q000008:administration & dosage / Q000009:adverse effects* / Q000493:pharmacokinetics; D013514:Surgical Procedures, Operative / Q000009:adverse effects*; D013923:Thromboembolism / Q000188:drug therapy / Q000209:etiology
chemical_list: D000925:Anticoagulants; D005343:Fibrinolytic Agents; D006490:Hemostatics; D010975:Platelet Aggregation Inhibitors