title: Unilateral pulmonary metastases from Ewing's sarcoma shown in a technetium-99m-methylene-diphosphonate bone scan.
abstract: A 32-year-old man with a history of painful swelling of the right ankle underwent bone scintigraphy, which showed increased uptake in the right ankle and also unexpected diffuse uptake throughout the right hemithorax. A single photon emission tomography scan performed after the intravenous injection of 740 MBq of technetium-99m methylene-diphosphonate ((99m)Tc-MDP) showed abnormal uptake throughout the right lung. Computed tomography (CT) revealed a large mass in the right lower lobe. CT-guided biopsy of this mass led to a diagnosis of metastatic Ewing's sarcoma. Although lung uptake on bone scans has been noted in various occasions (such as: pulmonary alveolar microlithiasis, Pneumocystis carinii pneumonia, and various tumoral lesions), increased uptake of (99m)Tc-MDP in lung metastases of Ewing's sarcoma has not been reported according to our knowledge until now. We report such a case.
authors.affiliation: Research Center for Nuclear Medicine, Tehran University of Medical Sciences, Shariati Hospital, 14114 Tehran, Iran. gholamrezanejhad@razi.tums.ac.ir
authors.forename: Ali
authors.initials: A
authors.lastname: Gholamrezanezhad
authors.forename: Davoud
authors.initials: D
authors.lastname: Moinian
authors.forename: Sahar
authors.initials: S
authors.lastname: Mirpour
authors.forename: Hadi
authors.initials: H
authors.lastname: Hajimohammadi
mesh_terms: D000328:Adult; D001859:Bone Neoplasms / Q000000981:diagnostic imaging*; D006801:Humans; D033162:Incidental Findings; D008168:Lung / Q000000981:diagnostic imaging*; D008175:Lung Neoplasms / Q000000981:diagnostic imaging* / Q000556:secondary*; D008297:Male; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals; D012512:Sarcoma, Ewing / Q000000981:diagnostic imaging* / Q000556:secondary*; D013669:Technetium Tc 99m Medronate
chemical_list: D019275:Radiopharmaceuticals; D013669:Technetium Tc 99m Medronate