Tissue engineering using adult stem cells.
Patients with a variety of diseases may be treated with transplanted tissues and organs. However, there is a shortage of donor tissues and organs, which is worsening yearly because of the aging population. Scientists in the field of tissue engineering are applying the principles of cell transplantation, material science, and bioengineering to construct biological substitutes that will restore and maintain normal function in diseased and injured tissues. The stem cell field is also advancing rapidly, opening new options for cellular therapy and tissue engineering. The use of adult stem cells for tissue engineering applications is promising. This chapter discusses applications of these new technologies for the engineering of tissues and organs. The first part provides an overview of regenerative medicine and tissue engineering techniques; the second highlights different adult stem cell populations used for tissue regeneration.
Eberli
Daniel
D
Wake Forest Institute for Regenerative Medicine, Winston Salem, North Carolina, USA.
Atala
Anthony
A
D053687:Adult Stem Cells / Q000145:classification / Q000637:transplantation*; D001842:Bone and Bones / Q000166:cytology; D002356:Cartilage / Q000166:cytology; D006801:Humans; D009206:Myocardium / Q000166:cytology; D023822:Tissue Engineering / Q000379:methods