Tamoxifen-induced severe hypertriglyceridaemia and acute pancreatitis.
Hypertriglyceridaemia is a well known risk factor for acute pancreatitis. Hypertriglyceridaemia may be primary in origin or secondary to alcohol abuse, diabetes mellitus, pregnancy or use of drugs. In this case report, the cause of acute pancreatitis was tamoxifen. We report on a patient with tamoxifen-induced acute pancreatitis and hypertriglyceridaemia who was successfully treated with insulin infusion and long-term gemfibrozil.
Alagozlu
Hakan
H
Department of Internal Medicine, Division of Gastroenterology, Medical Faculty of Gazi University, Ankara, Turkey. hakanalagoz@gazi.edu.tr
Cindoruk
Mehmet
M
Unal
Selahattin
S
D000208:Acute Disease; D004965:Estrogen Antagonists / Q000009:adverse effects / Q000627:therapeutic use; D005260:Female; D015248:Gemfibrozil / Q000627:therapeutic use; D006801:Humans; D015228:Hypertriglyceridemia / Q000139:chemically induced* / Q000175:diagnosis / Q000188:drug therapy; D000960:Hypolipidemic Agents; D007328:Insulin / Q000627:therapeutic use; D008875:Middle Aged; D010146:Pain / Q000139:chemically induced / Q000188:drug therapy; D010195:Pancreatitis / Q000139:chemically induced* / Q000175:diagnosis / Q000188:drug therapy; D013629:Tamoxifen / Q000009:adverse effects* / Q000627:therapeutic use; D016896:Treatment Outcome; D014839:Vomiting / Q000139:chemically induced / Q000188:drug therapy
D004965:Estrogen Antagonists; D000960:Hypolipidemic Agents; D007328:Insulin; D013629:Tamoxifen; D015248:Gemfibrozil