title: Prooxidant-antioxidant state of the organism during oxidative stress and correction of the L-arginine-NO system.
abstract: The prooxidant-antioxidant balance in rats with oxidative stress was studied during correction of the L-arginine-NO system. Oxidative stress was induced by intravenous injection of E. coli lipopolysaccharide. Under conditions of oxidative stress the prooxidant-antioxidant imbalance was least pronounced during selective correction of the L-arginine-NO system. L-Arginine and nonselective NO synthase inhibitor had little protective effect.
authors.affiliation: Department of Normal Physiology, Grodno Medical University.
authors.forename: A N
authors.initials: AN
authors.lastname: Glebov
authors.forename: V V
authors.initials: VV
authors.lastname: Zinchuk
mesh_terms: D000818:Animals; D000975:Antioxidants / Q000494:pharmacology*; D001120:Arginine / Q000737:chemistry*; D008070:Lipopolysaccharides / Q000378:metabolism; D008297:Male; D008954:Models, Biological; D009569:Nitric Oxide / Q000737:chemistry*; D018384:Oxidative Stress; D051381:Rats; D017382:Reactive Oxygen Species / Q000494:pharmacology*
chemical_list: D000975:Antioxidants; D008070:Lipopolysaccharides; D017382:Reactive Oxygen Species; D009569:Nitric Oxide; D001120:Arginine