[The comparison study of glaucoma trabeculectomy applying amniotic membrane or mitomycin C].
OBJECTIVE
To probe the results of trabeculectomy with human amniotic membrane (HAM) or mitomycin(MMC) in the treatment of glaucoma.


METHODS
In a randomized control clinical trial, 48 eyes of 28 glaucoma patients were divided into two groups, each group has 24 eyes, and each group was divided into two sub-groups according to the age. The former was underwent trabeculectomy with HAM transplanted, the later was administrated intra operatively with MMC, 0.2-0.4mg/ml, for 2-4 minutes, the follow-up was 6 months.


RESULTS
The operation success rate of both groups was higher than the standard trabeculectomy, and the difference between the two groups was not significant. Complications induced by HAM were mainly shallow anterior chamber, whereas by MMC were thin wall bleb, bleb leaking, persistent hypotony and hypotonous maculopathy.


CONCLUSIONS
Application properly HAM or MMC can improved the operation success rate, maintain the functional bleb long time and decreased the complications.
Zheng
Kangkeng
K
Department of Ophthalmology, Shantou Central Hospital, Guangdong Shantou 515031, China.
Huang
Zicai
Z
Zou
Haitang
H
Li
Hongni
H
Huang
Yixia
Y
Xie
Mingliang
M
D000368:Aged; D000650:Amnion / Q000637:transplantation*; D000963:Antimetabolites / Q000008:administration & dosage*; D005260:Female; D005500:Follow-Up Studies; D005901:Glaucoma / Q000188:drug therapy / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D016685:Mitomycin / Q000008:administration & dosage*; D014130:Trabeculectomy / Q000379:methods*; D016896:Treatment Outcome; D014792:Visual Acuity
D000963:Antimetabolites; D016685:Mitomycin