Effect of chalone system on proliferation of Ehrlich ascitic tumor cells under conditions of modified photoregimen.
We studied the influence of different photoregimens (light/darkness alternation and constant darkness) on the effect of saline and chalone regulation of cell proliferation in Ehrlich ascitic tumor was studied. Saline slightly inhibited proliferation of tumor cells. Chalone-containing preparations from animals exposed to light/darkness alternation and to constant darkness were characterized by different effects on cell proliferation in this tumor. Cell kinetics attested to possible mechanisms of the effect of the chalone system on the status of Ehrlich ascitic tumor; these mechanisms were independent on each other.
Mashanova
O G
OG
Russian State Medical University, Moscow. vladolg2004@mail.ru
Romanov
Yu A
YA
Evstafyev
V V
VV
Semyonova
M V
MV
D000818:Animals; D002286:Carcinoma, Ehrlich Tumor / Q000188:drug therapy* / Q000473:pathology*; D002453:Cell Cycle; D049109:Cell Proliferation; D050150:Chalones / Q000494:pharmacology*; D007700:Kinetics; D008027:Light; D008297:Male; D051379:Mice; D008938:Mitosis; D012965:Sodium Chloride / Q000494:pharmacology; D013997:Time Factors
D050150:Chalones; D012965:Sodium Chloride