Effect of delta sleep-inducing peptide on macromolecule biosynthesis in brain tissue of stressed rodents.
For evaluation of the nature of adaptogenic properties of delta sleep-inducing peptide we studied the effect of this substance on macromolecule biosynthesis in the brain of rats and mice exposed to burn injury and psychoemotional stress, respectively. Anabolic activity of delta sleep-inducing peptide depended on the purpose of adaptation corresponding to the type of stress.
Makletsova
M G
MG
Laboratory of Clinical Neurochemistry, Institute of Neurology, Russian Academy of Medical Sciences, Moscow.
Mikhaleva
I I
II
Prudchenko
I A
IA
Rikhireva
G T
GT
D000818:Animals; D001921:Brain / Q000187:drug effects*; D002056:Burns; D002540:Cerebral Cortex; D003701:Delta Sleep-Inducing Peptide / Q000494:pharmacology*; D046911:Macromolecular Substances; D008297:Male; D051379:Mice; D051381:Rats; D013095:Spermidine / Q000378:metabolism; D013096:Spermine / Q000378:metabolism; D013315:Stress, Psychological; D013997:Time Factors
D046911:Macromolecular Substances; D013096:Spermine; D003701:Delta Sleep-Inducing Peptide; D013095:Spermidine