title: [Determination of multiple pesticide residues in honey using gas chromatography-mass spectrometry].
abstract: An analytical method was developed for the simultaneous determination of 23 pesticide residues in various commercial honeys. Meanwhile, the characteristic ions and fragmentation mechanism of three pesticides in the process of electron ionization mass spectrometry (EI/MS) were evaluated. After the optimization of different parameters such as the extraction solvent, pesticides were extracted from honey with ethyl acetate in an ultrasonic bath, cleaned up on a Florisil column by an elution of mixture of hexane and ethyl acetate (7:3, v/v), and analyzed by gas chromatography-electron ionization mass spectrometry (GC-EI/MS) in the selected ion monitoring mode (SIM) with PCB103 as internal standard. Recovery studies were performed at 50, 100 and 200 microg/kg fortification levels for each pesticide, and the recoveries ranged from 82% to 120% with relative st0ndard deviations between 1.8% and 11.0% for different pesticides. The limit of detection was less than 10.0 microg/kg for all the pesticides. The developed method was linear in the range of 10-500 microg/kg, with correlation coefficients larger than 0.995. Finally, the developed analytical method has been successfully applied to the determination of pesticide residues in several honey samples.
authors.affiliation: Key Laboratory of Analytical Sciences of Ministry of Education, Department of Chemistry, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361005, China.
authors.forename: Zhen
authors.initials: Z
authors.lastname: Jin
authors.forename: Zhuguang
authors.initials: Z
authors.lastname: Lin
authors.forename: Meiyu
authors.initials: M
authors.lastname: Chen
authors.forename: Yu
authors.initials: Y
authors.lastname: Ma
authors.forename: Jun
authors.initials: J
authors.lastname: Tan
authors.forename: Yulan
authors.initials: Y
authors.lastname: Fan
authors.forename: Jiachen
authors.initials: J
authors.lastname: Weng
authors.forename: Zhaobin
authors.initials: Z
authors.lastname: Chen
authors.forename: Fengzhang
authors.initials: F
authors.lastname: Tu
mesh_terms: D008401:Gas Chromatography-Mass Spectrometry; D006722:Honey / Q000032:analysis*; D010573:Pesticide Residues / Q000032:analysis*
chemical_list: D010573:Pesticide Residues