title: [Clinical study of twenty-four-hour pattern of intraocular pressure in normal person and patient with primary open-angle glaucoma].
abstract: OBJECTIVE
  To characterize twenty-four-hour pattern of IOP in patients with primary open-angle glaucoma (POAG).
  
  
  METHODS
  Thirty persons of 40 to 65 years were selected in patients with POAG group. IOP were measured with Tono-pen tonometer within 24 hours. Measurements were taken every 2 hours in each eye (12 times in 24 hours). Both the sitting IOP and the supine IOP were measured between 7:00 and 23:00(once in 2 hours).
  
  
  RESULTS
  In both volunteers and patients with POAG, The lowest IOP occurred in 17: 30, the peak IOP occurred at 1:30. The value between trough and peak in twenty-four-hour pattern of the sitting and supine IOP was higher than the supine IOP.
  
  
  CONCLUSIONS
  The peak of IOP in most of patients with POAG occurred in the period of the sleeping time at night. Nocturnal intraocular of the patients with POAG pressure should be paid more attention.
authors.affiliation: Eye Hospital of Wenzhou Medical College, Wenzhou 325000, China.
authors.forename: Jinshun
authors.initials: J
authors.lastname: Zhang
authors.forename: Shouxiong
authors.initials: S
authors.lastname: Peng
authors.forename: Mingkai
authors.initials: M
authors.lastname: Lin
authors.forename: Chi
authors.initials: C
authors.lastname: Du
mesh_terms: D000328:Adult; D002940:Circadian Rhythm; D005260:Female; D005902:Glaucoma, Open-Angle / Q000503:physiopathology*; D006801:Humans; D007429:Intraocular Pressure / Q000502:physiology*; D008297:Male; D008875:Middle Aged; D011187:Posture / Q000502:physiology; D014065:Tonometry, Ocular / Q000379:methods