Automated detection of videotaped neonatal seizures based on motion tracking methods.
This study was carried out during the second phase of the project "Video Technologies for Neonatal Seizures" and aimed at the development of a seizure detection system by training neural networks, using quantitative motion information extracted by motion tracking methods from short video segments of infants monitored for seizures. The motion of the infants' body parts was quantified by temporal motion trajectory signals extracted from video recordings by robust motion trackers, based on block motion models. These motion trackers were developed to autonomously adjust to illumination and contrast changes that may occur during the video frame sequence. The computational tools and procedures developed for automated seizure detection were evaluated on short video segments selected and labeled by physicians from a set of 240 video recordings of 54 patients exhibiting myoclonic seizures (80 segments), focal clonic seizures (80 segments), and random infant movements (80 segments). This evaluation provided the basis for selecting the most effective strategy for training neural networks to detect neonatal seizures as well as the decision scheme used for interpreting the responses of the trained neural networks. The best neural networks exhibited sensitivity and specificity above 90%. The best among the motion trackers developed in this study produced quantitative features that constitute a reliable basis for detecting myoclonic and focal clonic neonatal seizures. The performance targets of the second phase of the project may be achieved by combining the quantitative features described in this paper with those obtained by analyzing motion strength signals produced by motion segmentation methods.
Karayiannis
Nicolaos B
NB
Department of Electrical and Computer Engineering, University of Houston, Houston, Texas, USA.
Xiong
Yaohua
Y
Frost
James D
JD
Wise
Merrill S
MS
Hrachovy
Richard A
RA
Mizrahi
Eli M
EM
D003936:Diagnosis, Computer-Assisted; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D009068:Movement / Q000502:physiology*; D016571:Neural Networks, Computer; D012640:Seizures / Q000175:diagnosis* / Q000503:physiopathology*; D012680:Sensitivity and Specificity; D012815:Signal Processing, Computer-Assisted; D013057:Spectrum Analysis; D014741:Video Recording / Q000379:methods*