title: [Pancreatoduodenectomy: results in a large volume center].
abstract: OBJECTIVE
  Analyze the experience with pancreaticoduodenectomy (PD) at the INCMNSZ.
  
  
  BACKGROUND
  PD has become a popular procedure in hospitals throughout the USA and Europe in the last 25 years, where mortality is < 5% y morbidity remains around 40%. Nonetheless there are very few reports on PD in Latin America.
  
  
  METHODS
  The data of all PD's performed at the INCMNSZ between 1999 and 2005 was gathered prospectively and analyzed retrospectively.
  
  
  RESULTS
  133 PDs where performed; 47.5% where men and 52.5% where women. Median of age was 57.7 years. 81.5% underwent classical resection and 18.5% a pylorus preserving procedure. Intraoperative variables include: blood loss: 940 mL. (1,000). transfusion requirements: 1.9 U, median operative time: 5:49 (+/- 1:02) and median hospital stay: 14 days. Most frequent diagnosis include ampulary adenocarcinoma and pancreatic cancer Mortality in the entire series was 9.2%, decreased to 2.7% in the 2002-2005 period and from April 2003 has remained in 0. A total of 14 portal-superior mesenteric vein resections where performed.
  
  
  CONCLUSIONS
  To our knowledge this is the largest series of PD in Latin America. Popularity and indications for PD are expanding. Mortality is acceptable and morbidity remains high despite much effort. This procedure is performed with a satisfactory outcome in high volume centers. Involvement of the portal-superior mesenteric vein is not a contraindication of PD.
authors.affiliation: Departamento de Cirugía General-Clínica de Páncreas, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirdn, México, D.F. carchan@quetzal.innsz.mx
authors.forename: Carlos
authors.initials: C
authors.lastname: Chan
authors.forename: Bernardo
authors.initials: B
authors.lastname: Franssen
authors.forename: Luis
authors.initials: L
authors.lastname: Uscanga
authors.forename: Guillermo
authors.initials: G
authors.lastname: Robles
authors.forename: Manuel
authors.initials: M
authors.lastname: Campuzano
mesh_terms: D000230:Adenocarcinoma / Q000601:surgery*; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D014670:Ampulla of Vater; D005260:Female; D006742:Hospital Bed Capacity; D006801:Humans; D008297:Male; D008875:Middle Aged; D010190:Pancreatic Neoplasms / Q000601:surgery*; D016577:Pancreaticoduodenectomy; D012189:Retrospective Studies