Photoinduced repair of a thymine dimer in DNA via carbazole nucleoside.
We report the photoinduced repair of a thymine dimer incorporated in a DNA duplex via oligodeoxynucleotide (ODN) containing carbazole nucleoside (K). The occurrence of an electron transfer between K and thymine dimer is evidenced by fluorescence quenching measurements. K acts as a good electron donor for the photoinduced repair of a thymine dimer.
Yoshimura
Yoshinaga
Y
School of Materials Science, Japan Advanced Institute of Science and Technology, 1-1 Asahidai, Nomi, Ishikawa 923-1292, Japan.
Fujimoto
Kenzo
K
D002851:Chromatography, High Pressure Liquid; D004247:DNA / Q000737:chemistry*; D004260:DNA Repair; D004583:Electrons; D009838:Oligodeoxyribonucleotides / Q000737:chemistry / Q000528:radiation effects; D010777:Photochemistry; D011740:Pyrimidine Dimers / Q000737:chemistry*; D012263:Ribonucleosides / Q000737:chemistry*
D009838:Oligodeoxyribonucleotides; D011740:Pyrimidine Dimers; D012263:Ribonucleosides; C522087:carbazole ribonucleoside; D004247:DNA