title: Surgical approach and clinical outcome of a deforming brown tumor at the maxilla in a patient with secondary hyperparathyroidism due to chronic renal failure.
abstract: Brown tumors are relatively uncommon but they are serious complications of renal osteodystrophy. We describe a 31-year-old woman with end-stage renal disease who had undergone hemodialysis for nine years and developed severe secondary hyperparathyroidism and a maxilla brown tumor despite increasing doses of oral calcitriol and calcium carbonate. The fast increase of the right maxillary bone tumor led to indication of parathyroidectomy (PTx). Despite normalization of serum PTH there was a slow regression of the mass and the patient still complained about her appearance after two-years of follow-up. Excision of the maxillary mass followed by recontouring of the maxilla was then performed, with adequate masticator rehabilitation.
authors.affiliation: Department of Endocrinology, University Hospital Clementino Fraga Filho, Federal University of Rio de Janeiro. christianneleal@terra.com.br
authors.forename: Christianne T S
authors.initials: CT
authors.lastname: Leal
authors.forename: Paulo G S
authors.initials: PG
authors.lastname: Lacativa
authors.forename: Elaine M S
authors.initials: EM
authors.lastname: Gomes
authors.forename: Reinaldo C
authors.initials: RC
authors.lastname: Nunes
authors.forename: Flávio Luiz F de S
authors.initials: FL
authors.lastname: Costa
authors.forename: Italo H A
authors.initials: IH
authors.lastname: Gandelmann
authors.forename: Maria A A
authors.initials: MA
authors.lastname: Cavalcante
authors.forename: Maria Lucia F
authors.initials: ML
authors.lastname: Farias
mesh_terms: D000328:Adult; D005260:Female; D006101:Granuloma, Giant Cell / Q000473:pathology / Q000601:surgery*; D006801:Humans; D006962:Hyperparathyroidism, Secondary / Q000209:etiology* / Q000473:pathology; D007676:Kidney Failure, Chronic / Q000150:complications* / Q000473:pathology; D008441:Maxillary Neoplasms / Q000473:pathology / Q000601:surgery*; D010281:Parathyroid Hormone / Q000032:analysis; D016105:Parathyroidectomy; D015898:Tomography Scanners, X-Ray Computed
chemical_list: D010281:Parathyroid Hormone