title: Fat microinfiltration autografting for facial restructuring in HIV patients.
abstract: BACKGROUND
  Antiretroviral drugs used to treat HIV infection are closely associated with faciocervical and peripheral lipodystrophies. There are several options for surgical treatment of facial lipodystrophy, one of these was described by S. R. Coleman in 1994, the technique of fat transplantation.
  
  
  METHODS
  A retrospective study of 23 seropositive patients is presented, who were treated according to Coleman's technique. The surgical procedure was evaluated by clinical and CT analysis. The longest follow-up was 3 years.
  
  
  RESULTS
  The technique was well tolerated from both a clinical and psychological point of view. 74% were successful. Multiple fat transplantation procedures were required to obtain a satisfactory result for the remaining patients. No complications were observed.
  
  
  CONCLUSIONS
  Coleman's method is very simple. It is performed without using any biomaterial. There are aesthetic and social benefits for the patients. A limitation of this procedure is that some patients do not have enough fat at the donor site.
  
  
  CONCLUSIONS
  The results of this procedure after a maximum of 3 years postoperatively have been positive. However, there is a need of long-term experience with this method.
authors.affiliation: Department of Maxillo-Facial and Oral Surgery, (Head: Prof. Dr. P. Goudot), University Hospital of Montpellier, France.
authors.forename: Sophie
authors.initials: S
authors.lastname: Domergue
authors.forename: Christina
authors.initials: C
authors.lastname: Psomas
authors.forename: Jacques
authors.initials: J
authors.lastname: Yachouh
authors.forename: Alvian
authors.initials: A
authors.lastname: Lesnik
authors.forename: Jacques
authors.initials: J
authors.lastname: Reynes
authors.forename: Patrick
authors.initials: P
authors.lastname: Goudot
authors.forename: Patrick
authors.initials: P
authors.lastname: Jammet
mesh_terms: D000273:Adipose Tissue / Q000637:transplantation*; D000328:Adult; D000368:Aged; D005145:Face / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D015658:HIV Infections / Q000188:drug therapy*; D017320:HIV Protease Inhibitors / Q000009:adverse effects*; D039682:HIV-Associated Lipodystrophy Syndrome / Q000139:chemically induced / Q000601:surgery*; D006801:Humans; D007271:Injections, Intradermal; D008297:Male; D008875:Middle Aged; D019651:Plastic Surgery Procedures / Q000379:methods; D012189:Retrospective Studies
chemical_list: D017320:HIV Protease Inhibitors