title: [On quality of life after surgical therapy of oral cancer - a retrospective multi-center study: the connection between dedentition, denture, quality of life, and dysphagia, and the resulting rehabilitation schemes].
abstract: OBJECTIVE
  The surgical treatment of oral cancer results in functional and aesthetical impairments. Patients' quality of life is considerably impaired by oral symptoms resulting from therapy of oral cancer. In many cases the inevitable resection of the tumor, as well as the adjuvant radiochemotherapy will cause the destruction of physiologically and anatomically important structures. One focus of research was the specific rehabilitation of dental loss by functional dentures. Another was the course of 19 impairments (comprehension of speech for unknown others, comprehension of speech for familiar others, eating/swallowing, mobility of the tongue, opening range of the mouth, mobility of lower jaw, mobility of neck, mobility of arms and shoulders, sense of taste, sense of smell, appearance, strength, appetite, respiration, pain, swelling, xerostomia, halitosis).
  
  
  METHODS
  Commissioned by the German, Austrian and Swiss cooperative group on tumors of the maxillofacial region (DOSAK), data were collected in 3.894 questionnaires at 43 hospitals in Germany, Austria and Switzerland. The catalogue comprised 147 items in 9 chapters. At the end of the enquiry, 1.761 anonymous questionnaires were returned by 38 hospitals. 1.652 of these could be evaluated regarding the question.
  
  
  RESULTS
  The sum score of the 19 impairments was highly increased immediately after the operation and recovered over the next 6 months, without, however, reaching the pre-surgery level. Of 1.652 patients, only 35% did not lose any teeth during therapy. 23% lost up to 5, 17% up to 10 teeth. A quarter of the patients lost more than 10 teeth. The more teeth were lost, the greater the decline of quality of life (p < or = 0.001), although this could be allayed by the functionality of the dentures (p < or = 0.001). There is a reciprocal dependence between the functionality of dental prosthetics and impairment by eating/swallowing (p < or = 0.001).
  
  
  CONCLUSIONS
  Patients' quality of life after radical surgery of a carcinoma of the oral cavity depends not only on the functionality of dentures and the specificity of rehabilitation, but also from the initial findings, the extent and location of the resection, the chosen therapy, the general circumstances of the patient's life as well as their strategies of coping. These factors, however, unlike those of functionality of dental prosthesis and rehabilitation, are not modifiable.
authors.affiliation: Heinrich-Heine-Universität Düsseldorf, Klinik für Kiefer- und Plastische Gesichtschirurgie, Düsseldorf, Germany. tobias.hahn@med.uni-duesseldorf.de
authors.forename: T R
authors.initials: TR
authors.lastname: Hahn
authors.forename: G
authors.initials: G
authors.lastname: Krüskemper
authors.forename: N
authors.initials: N
authors.lastname: Enkling
authors.forename: N R
authors.initials: NR
authors.lastname: Kübler
mesh_terms: D001317:Austria; D003680:Deglutition Disorders / Q000523:psychology* / Q000534:rehabilitation; D017266:Dental Prosthesis; D005858:Germany; D006801:Humans; D009062:Mouth Neoplasms / Q000523:psychology / Q000601:surgery*; D017060:Patient Satisfaction; D011183:Postoperative Complications / Q000523:psychology* / Q000534:rehabilitation; D011788:Quality of Life / Q000523:psychology*; D012189:Retrospective Studies; D011795:Surveys and Questionnaires; D013557:Switzerland; D016388:Tooth Loss / Q000523:psychology* / Q000534:rehabilitation