Clinical characteristics of corticobasal syndrome amongst Chinese in Taiwan.
This study reviewed the clinical characteristics of nine patients, the female-to-male ratio being 2 (6/3), with corticobasal syndrome (CBS) from 2001 to 2006. The mean age of onset was 60.33+/-5.20 years. The most popular symptom was rigidity (100%), followed by bradykinesia (88.89%), apraxia (88.89%) and dystonia (66.67%). The common presentations in neuropsychological assessment included frontal dysfunction (88.89%), disorientation (66.67%), memory impairments (66.67%) and visuospecial defects (66.67%). Single proton emission-computed tomography (CT) showed hypoperfusion at contralateral basal ganglia, thalamic, parietal or temporal region in eight of nine patients. This investigation suggests that functional neuroimages and neuropsychological tests are useful tools for the diagnosis of CBS.
Chang
Kuo-Hsuan
KH
Department of Neurology, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Linkou Medical Center, Taipei 10591, Taiwan.
Chuang
Chih-Ching
CC
Lyu
Rong-Kuo
RK
Chen
Chiung-Mei
CM
Ro
Long-Sun
LS
Chen
Sien-Tsong
ST
Wu
Yih-Ru
YR
D000368:Aged; D044466:Asian People; D001479:Basal Ganglia / Q000000981:diagnostic imaging / Q000473:pathology*; D001927:Brain Diseases / Q000000981:diagnostic imaging / Q000208:ethnology / Q000473:pathology* / Q000503:physiopathology*; D002540:Cerebral Cortex / Q000000981:diagnostic imaging / Q000473:pathology*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D012189:Retrospective Studies; D013624:Taiwan; D015899:Tomography, Emission-Computed, Single-Photon / Q000379:methods