Transplantation of conjunctival limbal autograft and amniotic membrane vs mitomycin C and amniotic membrane in treatment of recurrent pterygium.
OBJECTIVE
To compare the efficacy and complications of conjunctival limbal autograft (CLAU) and amniotic membrane transplantation (AMT) vsintraoperative mitomycin C (MMC) and AMT for treatment of recurrent pterygium.


METHODS
Forty eyes of 40 patients with recurrent pterygium underwent CLAU and AMT (20 eyes) or intraoperative MMC (0.02%, 3 min) and AMT (20 eyes). Three eyes (15%) had symblepharon before surgery in each group. Recurrence was compared in each group by using chi(2) test.


RESULTS
No major postoperative complications occurred during 6-19 months of follow-up. In CLAU/AMT group, no pterygium recurrence was observed. Recurrence occurred in four eyes (20%) in MMC/AMT group after 3 and 4 months (P-value=0.035, chi(2) test). No recurrence of pterygium or symblepharon was seen in six eyes with recurrent pterygium and symblepharon (three eyes in each group).


CONCLUSIONS
CLAU with AMT seems to be more effective than intraoperative MMC with AMT for treatment of recurrent pterygium.
Fallah
M R
MR
Department of Ophthalmology, Farabi Eye Hospital, Eye Research Center, Tehran University of Medical Science, Tehran, Iran.
Golabdar
M R
MR
Amozadeh
J
J
Zare
M A
MA
Moghimi
S
S
Fakhraee
G
G
D000328:Adult; D000368:Aged; D000650:Amnion / Q000637:transplantation*; D016009:Chi-Square Distribution; D003228:Conjunctiva / Q000637:transplantation*; D005260:Female; D006801:Humans; D016850:Limbus Corneae / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D016685:Mitomycin / Q000008:administration & dosage*; D011183:Postoperative Complications; D011625:Pterygium / Q000188:drug therapy / Q000601:surgery; D012008:Recurrence; D016896:Treatment Outcome
D016685:Mitomycin