What we have learned about Lyme borreliosis from studies in children.
Although pediatric Lyme borreliosis (LB) need not be a separate nosological entity, there are clinically important differences in presentation, antibiotic regimens and outcomes in children, which provide lessons that can be extrapolated to the disease as it affects adults. A large proportion of the worldwide data is obtained from children. The aim of this presentation is not to present an exhaustive review of the pediatric literature, but to review a selection of pediatric studies that have made a significant contribution to our body of knowledge in Lyme borreliosis.
Sood
Sunil K
SK
Pediatric Infectious Diseases, Schneider Children's Hospital at North Shore, Albert Einstein College of Medicine, Manhasset, NY 11030, USA. sood@lij.edu
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000658:Amoxicillin / Q000008:administration & dosage / Q000627:therapeutic use; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000627:therapeutic use; D025065:Borrelia burgdorferi / Q000276:immunology; D002444:Cefuroxime / Q000008:administration & dosage / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D002986:Clinical Trials as Topic; D003937:Diagnosis, Differential; D015787:Erythema Chronicum Migrans / Q000175:diagnosis; D005500:Follow-Up Studies; D006801:Humans; D015151:Immunoblotting; D007223:Infant; D008193:Lyme Disease / Q000175:diagnosis / Q000188:drug therapy / Q000276:immunology; D022123:Lyme Disease Vaccines / Q000008:administration & dosage / Q000276:immunology; D020852:Lyme Neuroborreliosis / Q000150:complications / Q000175:diagnosis; D015337:Multicenter Studies as Topic; D011446:Prospective Studies; D013997:Time Factors; D016896:Treatment Outcome
D000900:Anti-Bacterial Agents; D022123:Lyme Disease Vaccines; D000658:Amoxicillin; D002444:Cefuroxime