The non-peptidic HIV protease inhibitor tipranavir and two synthetic peptidomimetics (TS98 and TS102) modulate Pneumocystis carinii growth and proteasome activity of HEL299 cell line.
Mazza
Francesca
F
II Department of Infectious Diseases, L. Sacco Hospital, Milan, Italy.
Tronconi
Elisa
E
Valerio
Antonella
A
Groettrup
Marcus
M
Kremer
Marcel
M
Tossi
Alessandro
A
Benedetti
Fabio
F
Cargnel
Antonietta
A
Atzori
Chiara
C
D000818:Animals; D000935:Antifungal Agents / Q000494:pharmacology*; D002460:Cell Line; D003374:Coumarins / Q000378:metabolism; D017320:HIV Protease Inhibitors / Q000494:pharmacology*; D006801:Humans; D009842:Oligopeptides / Q000378:metabolism; D045363:Pneumocystis carinii / Q000187:drug effects* / Q000254:growth & development; D011480:Protease Inhibitors / Q000494:pharmacology*; D046988:Proteasome Endopeptidase Complex / Q000187:drug effects*; D061988:Proteasome Inhibitors; D011725:Pyridines / Q000494:pharmacology*; D011753:Pyrones / Q000494:pharmacology*; D051381:Rats; D013449:Sulfonamides
D000935:Antifungal Agents; D003374:Coumarins; D017320:HIV Protease Inhibitors; C114703:N-succinyl-leucyl-leucyl-valyl-tyrosyl-7-amino-4-methylcoumarin; D009842:Oligopeptides; D011480:Protease Inhibitors; D061988:Proteasome Inhibitors; D011725:Pyridines; D011753:Pyrones; D013449:Sulfonamides; D046988:Proteasome Endopeptidase Complex; C107201:tipranavir