title: [Prognostic impact of anemia in acute heart failure].
abstract: OBJECTIVE
  Studies performed on selected patients in other countries have shown that anemia is frequently associated with heart failure and results in a worse prognosis. We sought to determine the prognosis significance of hemoglobin/anemia in patients with acute heart failure which required management with hospital admission.
  
  
  METHODS
  We analysed 412 patients diagnosed with acute heart failure as outlined in the criteria of the European Society of Cardiology (ESC). We measured hemoglobin within the first 24 hours and obtained demographic, clinical and biochemical variables. Anemia was defined in accordance with OMS criteria. The main variable was all-cause mortality. The association between all-cause mortality and hemoglobin/anemia was determined using the multiple regression Cox model.
  
  
  RESULTS
  During follow-up (median six months) we observed 101 all-cause mortality events. In the multivariate analysis, hemoglobin was an independent predictive variable adjusted by covariates (HR 1.15, IC 95% [1.04-1.25], p = 0.014). Anemia (hemoglobin < 13 g/dL) was also found to be an independent predictive variable adjusted by covariates (HR 2.06, IC al 95% [1.28-3.33], p = 0.003).
  
  
  CONCLUSIONS
  Hemoglobin and anemia (hemoglobin < 13 g/dL) are consistently associated with short-term, poorer survival in patients with acute heart failure.
authors.affiliation: Servicio de Cardiología, Hospital Clinico de Valencia, Valencia, España. lconsue@hotmail.com
authors.forename: Luciano
authors.initials: L
authors.lastname: Consuegra-Sánchez
authors.forename: Julio
authors.initials: J
authors.lastname: Núñez
authors.forename: Lorenzo
authors.initials: L
authors.lastname: Fácila
authors.forename: Lorenza
authors.initials: L
authors.lastname: Fácila
authors.forename: Vicente
authors.initials: V
authors.lastname: Bertomeu
authors.forename: Rocío
authors.initials: R
authors.lastname: Robles
authors.forename: Angel
authors.initials: A
authors.lastname: Llácer
mesh_terms: D000368:Aged; D000740:Anemia / Q000150:complications* / Q000401:mortality; D005260:Female; D006333:Heart Failure / Q000150:complications* / Q000401:mortality; D006801:Humans; D008297:Male; D011379:Prognosis; D011446:Prospective Studies; D016019:Survival Analysis