Intraoperative cytology of clear cell carcinoma of the ovary.
OBJECTIVE
To describe the cytomorphology of clear cell carcinoma (CCC) of the ovary in intraoperative samples of peritoneal fluid, imprint and scraping samples of the tumour tissue.


METHODS
Fourteen histologically confirmed cases, stained by standard cytological procedures, were analysed by light microscopy.


RESULTS
In 33.3% of peritoneal fluid samples and 92.9% of imprint and scraping cytological samples, besides variable clear cell cellular morphology, one or both distinct cytological characteristics were observed: eosinophilic, hyaline, extracellular, globular substance with or without formation of a 'raspberry' body and an eosinophilic, intracytoplasmic inclusions. These structures were clearly seen only in samples stained by May-Grünwald-Giemsa.


CONCLUSIONS
Using cytological analysis of imprint and scraping samples of ovarian tumours it is possible to make a precise intraoperative cytological diagnosis in most cases of CCC of the ovary.
Vrdoljak-Mozetic
D
D
Department of Gynecological Cytology, Unviersity Department of Gynecology and Obstetrics, University Hospital Center Rijeka, Rijeka, Croatia. danijela.vrdoljak-mozetic@ri.htnet.hr
Stanković
T
T
Krasević
M
M
Versa-Ostojić
D
D
Stemberger-Papić
S
S
Rupcić
S
S
D018262:Adenocarcinoma, Clear Cell / Q000473:pathology* / Q000601:surgery; D001202:Ascitic Fluid / Q000473:pathology; D005260:Female; D006801:Humans; D007430:Intraoperative Care; D010051:Ovarian Neoplasms / Q000473:pathology* / Q000601:surgery