title: [A case of malignant mesothelioma presenting with recurrent pneumothorax].
abstract: A 71-year-old man was found to have right hydropneumothorax by chest X-ray film on a regular checkup. Thoracic drainage and bullectomy by thoracoscopy did not improve the pneumothorax, so pleurodesis with OK-432 was done. Pneumothorax recurred twice, requiring thoracic drainage and pleurodesis. Although pneumothorax was treated successfully, increased pleural effusion, pleural thickening and subcutaneal tumor at the thoracic drainage suture site developed. The concentration of hyaluronic acid in the pleural fluid was very high. The histological examination of the biopsied subcutaneous tumor showed mixed type malignant pleural mesothelioma. Chemotherapy with gemcitabine and vinorelbine could not control the progression.
authors.affiliation: Department of Respiratory Medicine, Kanazawa Municipal Hospital.
authors.forename: Nobuyuki
authors.initials: N
authors.lastname: Katayam
authors.forename: Akira
authors.initials: A
authors.lastname: Tokuda
authors.forename: Yasuto
authors.initials: Y
authors.lastname: Nakatsumi
authors.forename: Yoshitaka
authors.initials: Y
authors.lastname: Oribe
authors.forename: Masaki
authors.initials: M
authors.lastname: Fujimura
mesh_terms: D000368:Aged; D000970:Antineoplastic Agents / Q000627:therapeutic use; D018450:Disease Progression; D017809:Fatal Outcome; D006801:Humans; D008297:Male; D008654:Mesothelioma / Q000175:diagnosis* / Q000473:pathology; D010844:Picibanil / Q000627:therapeutic use; D010997:Pleural Neoplasms / Q000175:diagnosis* / Q000473:pathology; D011030:Pneumothorax / Q000000981:diagnostic imaging / Q000209:etiology* / Q000628:therapy; D011859:Radiography; D012008:Recurrence
chemical_list: D000970:Antineoplastic Agents; D010844:Picibanil