title: Lifetime comorbidity of obsessive-compulsive disorder with psychiatric disorders in a community sample.
abstract: Epidemiological research indicates that obsessive-compulsive disorder (OCD) still constitutes a major public health problem. To study the comorbidity of psychiatric disorders in OCD subjects in a non-Western community sample, 25,180 individuals were interviewed face-to-face at home according to DSM-IV for diagnosis of psychiatric disorders by 250 trained clinical psychologists. The subjects were predetermined with a randomized cluster sampling method among all families residing in Iran. From 444 individuals diagnosed as OCD, 157 (35.4%) developed at least one of the psychiatric disorders. The most common comorbid psychiatric disorders were major depressive disorder and simple phobia. Comorbidity of two or more additional psychiatric disorders in OCD individuals was rare. There was no difference between genders in the comorbidity of psychiatric disorders with OCD. Low comorbidity of psychiatric disorders with OCD shows that OCD tends to occur in isolated rather than as cluster problems in a clinical sample.
authors.affiliation: Department of Psychiatry, Psychiatry and Psychology Research Center, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Mohammad-Reza
authors.initials: MR
authors.lastname: Mohammadi
authors.forename: Ahmad
authors.initials: A
authors.lastname: Ghanizadeh
authors.forename: Rozita
authors.initials: R
authors.lastname: Moini
mesh_terms: D000328:Adult; D001008:Anxiety Disorders / Q000175:diagnosis / Q000453:epidemiology*; D015897:Comorbidity; D003866:Depressive Disorder / Q000175:diagnosis / Q000453:epidemiology*; D039721:Diagnostic and Statistical Manual of Mental Disorders; D005260:Female; D006801:Humans; D008297:Male; D009771:Obsessive-Compulsive Disorder / Q000453:epidemiology*; D015995:Prevalence; D012559:Schizophrenia / Q000175:diagnosis / Q000453:epidemiology*