title: Synthesis and base recognition ability of oligoribonucleotides incorporating 2'-O-methyl-3-deazaguanosine.
abstract: 2'-O-methyl-oligoribonucleotides incorporating a 3-deazaguanine (3DG) were synthesized. Melting temperature (Tm value) analysis indicates the stability and base discriminating ability of the 2'-O-methyl-RNA/RNA duplex.
authors.affiliation: Frontier Collaborative Research Center, Tokyo Institute of Technology, Nagatsuda, Midoriku, Yokohama 226-8503, Japan.
authors.forename: Kohji
authors.initials: K
authors.lastname: Seio
authors.forename: Takeshi
authors.initials: T
authors.lastname: Sasami
authors.forename: Mitsuo
authors.initials: M
authors.lastname: Sekine
mesh_terms: D020137:Base Pair Mismatch; D020029:Base Pairing; D006151:Guanosine / Q000031:analogs & derivatives* / Q000737:chemistry; D009843:Oligoribonucleotides / Q000138:chemical synthesis* / Q000737:chemistry*
chemical_list: C521144:2'-O-methyl-3-deazaguanosine; D009843:Oligoribonucleotides; D006151:Guanosine; C010568:3-deazaguanosine