[French survey about intradermal BCG SSI adverse events in children under 6 years of age].
During April 2006, 579 physicians took part in a survey about intradermal BCG SSI adverse events (AE) in children less than 6 years old, managed by InfoVac France. Since January 2006, 68% physicians (paediatricians: 73% and general practitioners [GP]: 60%) have vaccinated at least one child. The site of injection is mainly the extern side of the shoulder (72%), according to the recommendations. Systematic vaccination is continued by 54% GP and 26% paediatricians. Others indications are: admission in day care center (33%), admission in day care center associated with risk factors (24%), or only risks factors (8%). Half physicians observed AE and 6% of them reported them at pharmacovigilance centers or pharmaceutical company. AE were mainly inflammations or indurations over 1 cm (for 75% of physicians who observed AE), oozing (73%). Abscesses are notified by 54%, ulcers by 39%, lymphadenopathies over 1 cm by 20%, suppurative lymphadenopathies by 3% and keloid scares by 17% of them, several AE may coexist for some children. Our aim is to start a prospective follow-up of BCG-SSI vaccination and its AE; 58% physicians who answered this investigation agreed to participate.
Dommergues
M-A
MA
Service de pédiatrie, hôpital André-Mignot, 177, rue de Versailles, 78157 Le Chesnay cedex, France. madommergues@wanadoo.fr
de la Rocque
F
F
Dufour
V
V
Floret
D
D
Gaudelus
J
J
Guérin
N
N
Le Sage
F-V
FV
Bocquet
A
A
Cohen
R
R
D016907:Adverse Drug Reaction Reporting Systems; D001500:BCG Vaccine / Q000008:administration & dosage / Q000009:adverse effects*; D002648:Child; D002675:Child, Preschool; D005602:France; D006801:Humans; D007271:Injections, Intradermal; D012189:Retrospective Studies; D011795:Surveys and Questionnaires
D001500:BCG Vaccine