title: Clinical evaluation of a new self-drying silicone gel in the treatment of scars: a preliminary report.
abstract: Topical silicone gel sheeting and intralesional steroids are the only evidence-based recommendable forms of treatment to control the quality of a scar. The advantages and disadvantages of both are well known. This study was undertaken to verify the efficacy of a new topical silicone treatment: a self-drying spreadable gel that needs no means of fixation and cannot be seen because of complete transparency. Fresh surgical scars treated with the tested product showed significantly better outcomes than those untreated in a prospective trial involving a group of 160 patients. Patient compliance was particularly good, especially for scars on exposed areas such as the face, where the traditional gel sheeting is frequently discontinued at an early stage by patients who object to its visibility. The results of the self-drying silicone gel have indeed been satisfactory. Considering the effective results obtained and the good patient compliance, the authors currently rate this concept of treatment as the first choice for preventing hypertrophy of recent scars.
authors.affiliation: Istituto Dermatologico Europeo, Milano, Italy.
authors.forename: Massimo
authors.initials: M
authors.lastname: Signorini
authors.forename: Matteo Tretti
authors.initials: MT
authors.lastname: Clementoni
mesh_terms: D000287:Administration, Topical; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000556:Ambulatory Surgical Procedures; D002648:Child; D002675:Child, Preschool; D017439:Cicatrix, Hypertrophic / Q000628:therapy*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007558:Italy; D007627:Keloid / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D009779:Occlusive Dressings; D011183:Postoperative Complications / Q000517:prevention & control*; D012189:Retrospective Studies; D020034:Silicone Gels / Q000008:administration & dosage*
chemical_list: D020034:Silicone Gels