title: Dynamometry of intrinsic hand muscles in patients with Charcot-Marie-Tooth disease.
abstract: BACKGROUND
  Several problems are associated with manual muscle testing and dynamometry in the hands of patients with Charcot-Marie-Tooth (CMT) disease.
  
  
  OBJECTIVE
  To evaluate the efficacy of the Rotterdam Intrinsic Hand Myometer (RIHM) to directly measure intrinsic hand muscle strength in CMT disease.
  
  
  METHODS
  We measured hand muscle strength and hand function in 41 patients with CMT disease.
  
  
  RESULTS
  RIHM measurement of intrinsic strength had excellent reliability. We found overlapping RIHM strength values in Medical Research Council grades 3 to 5. High grip and pinch strength could be found in patients with severe intrinsic muscle weakness. RIHM measurements were more strongly correlated with fine motor skills of the hand than grip and pinch strength.
  
  
  CONCLUSIONS
  The Rotterdam Intrinsic Hand Myometer is a reliable instrument to measure intrinsic hand muscles strength in patients with Charcot-Marie-Tooth disease, providing more detailed information than manual muscle testing and a more direct assessment of intrinsic muscle loss than grip and pinch dynamometers.
authors.affiliation: Department of Rehabilitation Medicine, Erasmus MC-University Medical Center Rotterdam, Rm. h.016, PO Box 2040, 3000 CA Rotterdam, the Netherlands. r.selles@erasmusmc.nl
authors.forename: R W
authors.initials: RW
authors.lastname: Selles
authors.forename: B T J
authors.initials: BT
authors.lastname: van Ginneken
authors.forename: T A R
authors.initials: TA
authors.lastname: Schreuders
authors.forename: W G M
authors.initials: WG
authors.lastname: Janssen
authors.forename: H J
authors.initials: HJ
authors.lastname: Stam
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002607:Charcot-Marie-Tooth Disease / Q000175:diagnosis / Q000503:physiopathology*; D005260:Female; D006225:Hand / Q000502:physiology; D018737:Hand Strength / Q000502:physiology*; D006801:Humans; D007537:Isometric Contraction / Q000502:physiology; D008297:Male; D008875:Middle Aged; D053581:Muscle Strength Dynamometer; D018482:Muscle, Skeletal / Q000502:physiology*; D009213:Myography / Q000379:methods