title: Tricarboranyl pentaerythritol-based building block.
abstract: A new tricarborane building block based on pentaerythritol was prepared for applications in boron neutron capture therapy (BNCT). Its X-ray single-crystal structure revealed a high degree of steric congestion. To enable the attachment of the building block to other moieties, a succinimidyl linker has been introduced at the focal point, and a generation-2 hexacarborane-containing dendron carrying 60 boron atoms has been prepared using a 2,2-bis(hydroxymethyl)propionic acid core.
authors.affiliation: Department of Chemistry, University of Utah, Salt Lake City, Utah 84112, USA.
authors.forename: Alexis
authors.initials: A
authors.lastname: Mollard
authors.forename: Ilya
authors.initials: I
authors.lastname: Zharov
mesh_terms: D001896:Boron Compounds / Q000138:chemical synthesis*; D016754:Boron Neutron Capture Therapy / Q000379:methods*; D018360:Crystallography, X-Ray; D008956:Models, Chemical; D011422:Propionates / Q000737:chemistry; D011409:Propylene Glycols / Q000138:chemical synthesis*; D013237:Stereoisomerism; D013388:Succinimides / Q000737:chemistry
chemical_list: D001896:Boron Compounds; D011422:Propionates; D011409:Propylene Glycols; D013388:Succinimides; C008783:pentaerythritol