title: Case report: primary infection by human herpesvirus 6 variant a with the onset of myelitis.
abstract: A case of primary infection by human herpesvirus 6 (HHV-6) variant A in a 54-year-old woman, which occurred at the same time as the onset of encephalomyelitis, is reported. The correlation between the two events is discussed. It is speculated that, during the early phase of the infection, the HHV-6 spread to the central nervous system and triggered a pathogenic process that initially developed without symptoms. When the neurological disorders appeared, HHV-6 had already established a latent state: only the virus carried by infected blood cells was detected in the cerebrospinal fluid.
authors.affiliation: Department of Diagnostic Services and Legal Medicine, University of Moderna and Reggio Emilia, Modena, Italy. portolani.marinella@policlinico.mo.it
authors.forename: Marinella
authors.initials: M
authors.lastname: Portolani
authors.forename: Monica
authors.initials: M
authors.lastname: Pecorari
authors.forename: William
authors.initials: W
authors.lastname: Gennari
authors.forename: Francesca
authors.initials: F
authors.lastname: Beretti
authors.forename: Anna Maria Teresa
authors.initials: AM
authors.lastname: Sabbatini
authors.forename: Chiara
authors.initials: C
authors.lastname: Casolari
authors.forename: Fabio
authors.initials: F
authors.lastname: Rumpianesi
authors.forename: Claudio
authors.initials: C
authors.lastname: Cermelli
authors.forename: Michele
authors.initials: M
authors.lastname: Sintini
authors.forename: Fernanda
authors.initials: F
authors.lastname: Mori
mesh_terms: D002574:Cervical Vertebrae / Q000000981:diagnostic imaging; D004279:DNA, Viral / Q000097:blood / Q000134:cerebrospinal fluid; D004679:Encephalomyelitis / Q000000981:diagnostic imaging / Q000821:virology*; D005260:Female; D014644:Genetic Variation; D015654:Herpesvirus 6, Human / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification*; D006801:Humans; D008875:Middle Aged; D011859:Radiography; D019349:Roseolovirus Infections / Q000150:complications* / Q000000981:diagnostic imaging / Q000821:virology
chemical_list: D004279:DNA, Viral