title: Molecular pathogenesis of severe acute respiratory syndrome.
abstract: The global outbreak in 2002-2003 of severe acute respiratory syndrome (SARS) posed a serious threat to public health and had a significant impact on socioeconomic stability. Although the global outbreak of SARS has been contained, there are serious concerns over its re-emergence and bioterrorism potential, and up to date, no specific treatment exists for this disease. Here we review the progress of studies on the pathogenesis of the disease, in particular, studies on the molecular level.
authors.affiliation: National Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Peking Union Medical College and Chinese Academy of Medical Sciences, 5 Dongdan Santiao, Beijing 100005, China.
authors.forename: Hongliang
authors.initials: H
authors.lastname: Wang
authors.forename: Shuan
authors.initials: S
authors.lastname: Rao
authors.forename: Chengyu
authors.initials: C
authors.lastname: Jiang
mesh_terms: D000818:Animals; D018450:Disease Progression; D006801:Humans; D051379:Mice; D045473:Severe acute respiratory syndrome-related coronavirus / Q000235:genetics / Q000378:metabolism / Q000472:pathogenicity / Q000502:physiology*; D045169:Severe Acute Respiratory Syndrome / Q000276:immunology / Q000473:pathology / Q000628:therapy / Q000821:virology*; D014765:Viral Vaccines / Q000627:therapeutic use
chemical_list: D014765:Viral Vaccines