title: Cerebral lipiodol embolism: a complication of transcatheter arterial chemoembolization for hepatocellular carcinoma.
abstract: We report a case of cerebral lipiodol embolism following transcatheter chemoembolization (TACE) for hepatocellular carcinoma. A 70-year-old woman with a large unresectable hepatocellular carcinoma underwent TACE. Her level of consciousness deteriorated after the procedure, and magnetic resonance imaging and non-contrast computed tomography revealed a cerebral lipiodol embolism. Despite intensive care, the patient died 2 weeks later. The complication might have been due to systemic-pulmonary shunts caused by previous surgeries and/or direct invasion of the recurrent tumor.
authors.affiliation: Department of Radiology, Saga Medical School, 5-1-1 Nabeshima, Saga, 849-8501, Japan. matsumk2@cc.saga-u.ac.jp
authors.forename: Koichi
authors.initials: K
authors.lastname: Matsumoto
authors.forename: Junichi
authors.initials: J
authors.lastname: Nojiri
authors.forename: Yukinori
authors.initials: Y
authors.lastname: Takase
authors.forename: Yoshikazu
authors.initials: Y
authors.lastname: Egashira
authors.forename: Shinichi
authors.initials: S
authors.lastname: Azama
authors.forename: Akira
authors.initials: A
authors.lastname: Kato
authors.forename: Kenji
authors.initials: K
authors.lastname: Kitahara
authors.forename: Koji
authors.initials: K
authors.lastname: Miyazaki
authors.forename: Sho
authors.initials: S
authors.lastname: Kudo
mesh_terms: D000368:Aged; D001921:Brain / Q000187:drug effects / Q000473:pathology; D006528:Carcinoma, Hepatocellular / Q000628:therapy*; D016461:Chemoembolization, Therapeutic / Q000009:adverse effects*; D003287:Contrast Media / Q000008:administration & dosage / Q000009:adverse effects*; D003952:Diagnostic Imaging; D015251:Epirubicin / Q000008:administration & dosage; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D020766:Intracranial Embolism / Q000139:chemically induced* / Q000175:diagnosis; D007459:Iodized Oil / Q000009:adverse effects*; D008113:Liver Neoplasms / Q000628:therapy*; D009364:Neoplasm Recurrence, Local / Q000628:therapy*
chemical_list: D003287:Contrast Media; D015251:Epirubicin; D007459:Iodized Oil