title: [Case of cutaneous necrosis in African clawed frogs Xenopus laevis after the topical application of eugenol].
abstract: Case of cutaneous necrosis in African Clawed frogs Xenopus laevis after the topical application of eugenol. African Clawed frogs showed necrotic cutaneous lesions after a topical application of high concentrations of eugenol, an analgesic and anesthetic agent. Microscopically, ulceration of the epidermis, a loss of mucous and serous glands as well as an infiltration of inflammatory cells were observed.
authors.affiliation: Université de Montréal, Faculté de médecine vétérinaire, Départements de biomédecine vétérinaire, de pathologie et de microbiologie, C.P. 5000, Saint-Hyacinthe, Québec.
authors.forename: Andréanne
authors.initials: A
authors.lastname: Ross
authors.forename: Sarah Annie
authors.initials: SA
authors.lastname: Guénette
authors.forename: Pierre
authors.initials: P
authors.lastname: Hélie
authors.forename: Pascal
authors.initials: P
authors.lastname: Vachon
mesh_terms: D000287:Administration, Topical; D000818:Animals; D004305:Dose-Response Relationship, Drug; D005054:Eugenol / Q000009:adverse effects*; D012867:Skin / Q000187:drug effects* / Q000473:pathology; D012871:Skin Diseases / Q000139:chemically induced / Q000473:pathology / Q000662:veterinary*; D014982:Xenopus laevis
chemical_list: D005054:Eugenol