The comparison study of renin and angiotensin A II levels on normal tension glaucoma patients and normal individuals.
OBJECTIVE
To investigate the levels of renin-angiotension system (RAS) components in normal tension glaucoma patients and normal controls.


METHODS
Blood samples were obtained from 11 normal tension glaucoma(NTG)patients and 11 age and sex matched controls. The levels of renin and angiotensin A II of 11 NTG patients and normal controls were examined by radio-immunity test. Statistical analyses were performed by paired t test.


RESULTS
The levels of renin of NTG patients and normal controls are (769.085+/-183.217) pg/ml/n and (822.035+/-124.140) pg/ml/n, while the levels of angiotensin A II of NTG patients and normal controls are (37.347+/-10.669) pg/ml and (24.836+/-10.665) pg/ml respectively. No statistically significant differences were observed between the levels of renin and angiotensin among NTG patients and normal controls.


CONCLUSIONS
There were not many abnormalities of the levels of circulating rennin and angiotensin A II of NTG patients in our study.
Yun
Hongmin
H
Department of Ophthalmology, Peking University Shenzhen Hospital, Shenzhen 518036, China.
Fu
Pei
P
Ding
Kexi
K
Yang
Qi
Q
D000328:Adult; D000809:Angiotensins / Q000097:blood*; D016022:Case-Control Studies; D005260:Female; D005901:Glaucoma / Q000097:blood*; D006801:Humans; D007429:Intraocular Pressure; D008297:Male; D012083:Renin / Q000097:blood*
D000809:Angiotensins; C516880:angiotensin A; D012083:Renin