title: [Is Widal syndrome always a severe disease?].
abstract: BACKGROUND
  the Widal syndrome (WS) is known as the association of bronchial asthma to aspirin intolerance, nasal polyposis and/or allergic rhinitis, typical considered to have a difficult course.
  
  
  OBJECTIVE
  finding the prevalence and severity of WS in general medical practice. VENUE: data bases from a private pneumology practice and the ambulatory of a pneumology clinic in Timisoara.
  
  
  METHODS
  473 asthma patients, among which 41 (8.66%) matched the criteria for WS. There were 31 women (75.6%) and 10 men (24.39%). MAIN PARAMETERS EVALUATED: spirometry, ENT examination, skin allergy tests, serum IgE.
  
  
  RESULTS
  most cases (22 pts., 53.65%) had mild to moderate asthma. Monitoring the cases for 4 years didn't show any worsening. The 19 severe cases (46.35%) had a progressive course, despite a complex treatment (anti-leukotrienes + systemic corticosteroids in high doses + long acting beta 2 agonists + long acting theophylline). The results don't match the classical description of WS, with a dominance of severe forms.
  
  
  CONCLUSIONS
  in general medical practice WS has a frequency of 8.66% among asthmatic population, and the mild and moderate forms represent 53.65% and it seems they keep like that a long time.
authors.affiliation: Clinica de Pneumologie, U.M.F. Timişoara. vtudorache@mail.dnttm.ro
authors.forename: Voicu
authors.initials: V
authors.lastname: Tudorache
authors.forename: S
authors.initials: S
authors.lastname: Mihăicuţă
authors.forename: Rodica
authors.initials: R
authors.lastname: Potre
authors.forename: Eugen
authors.initials: E
authors.lastname: Melcescu
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects*; D001241:Aspirin / Q000009:adverse effects*; D001249:Asthma / Q000139:chemically induced / Q000175:diagnosis / Q000453:epidemiology*; D002908:Chronic Disease; D004342:Drug Hypersensitivity / Q000150:complications*; D005260:Female; D006801:Humans; D007073:Immunoglobulin E / Q000097:blood; D008297:Male; D008499:Medical Records; D008875:Middle Aged; D009298:Nasal Polyps / Q000175:diagnosis / Q000453:epidemiology*; D015995:Prevalence; D011379:Prognosis; D012221:Rhinitis, Allergic, Perennial / Q000453:epidemiology; D012383:Romania / Q000453:epidemiology; D012720:Severity of Illness Index; D013147:Spirometry; D013577:Syndrome
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D007073:Immunoglobulin E; D001241:Aspirin