title: Patient functioning and family burden in a controlled, real-world trial of family psychoeducation for schizophrenia.
abstract: OBJECTIVE
  This study explored the effectiveness of a psychoeducational family intervention for schizophrenia on patients' personal and social functioning as well as on relatives' burden and perceived support.
  
  
  METHODS
  Thirty-four mental health professionals from 17 public mental health centers in Italy selected 71 families of consumers with schizophrenia. Forty-two families were randomly assigned to a group that received the intervention for six months, and 29 families were assigned to a waiting list for six months. At baseline and six months later, validated tools were used to assess patients' clinical status, personal and social functioning, and social network as well as relatives' burden, social resources, and perception of professional support.
  
  
  RESULTS
  In the intervention group the number of patients with poor or very poor global personal and social functioning decreased significantly, from 17 (47 percent) at baseline to nine (25 percent) at follow-up. A significant improvement was found for the intervention group in patients' social relationships, interests in obtaining a job, maintenance of social interests, and management of social conflicts. Twenty-seven patients (74 percent) reported that their social relationships had improved during the six-month period. For both the intervention and control groups, family burden significantly improved. Relatives' social contacts and perception of professional support significantly increased only in the intervention group.
  
  
  CONCLUSIONS
  The results suggest that a psychoeducational family intervention may have a significant impact on functional outcomes of schizophrenia when provided to patients and caregivers in real-world settings.
authors.affiliation: Department of Psychiatry, Second University of Naples SUN, Largo Madonna delle Grazie, Naples I-80138, Italy. lorenza. magliano@unina2.it
authors.forename: Lorenza
authors.initials: L
authors.lastname: Magliano
authors.forename: Andrea
authors.initials: A
authors.lastname: Fiorillo
authors.forename: Claudio
authors.initials: C
authors.lastname: Malangone
authors.forename: Corrado
authors.initials: C
authors.lastname: De Rosa
authors.forename: Mario
authors.initials: M
authors.lastname: Maj
mesh_terms: D000328:Adult; D017028:Caregivers / Q000193:education* / Q000523:psychology; D017281:Cost of Illness; D005190:Family / Q000523:psychology*; D005260:Female; D005500:Follow-Up Studies; D006266:Health Education / Q000379:methods*; D006801:Humans; D007558:Italy; D008297:Male; D010465:Perception / Q000502:physiology; D011569:Psychiatric Status Rating Scales / Q000706:statistics & numerical data; D011788:Quality of Life / Q000523:psychology*; D012559:Schizophrenia / Q000534:rehabilitation*; D012565:Schizophrenic Psychology; D012919:Social Behavior; D012944:Social Support; D012959:Socioeconomic Factors