title: Lethal toxicity of uracil/tegafur in the treatment of sigmoid carcinoma.
authors.forename: T M
authors.initials: TM
authors.lastname: Bosch
authors.forename: I
authors.initials: I
authors.lastname: Meijerman
authors.forename: J H
authors.initials: JH
authors.lastname: Beijnen
authors.forename: S W
authors.initials: SW
authors.lastname: van Thiel
authors.forename: L T
authors.initials: LT
authors.lastname: Vlasveld
mesh_terms: D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects* / Q000378:metabolism; D001189:Aryl Hydrocarbon Hydroxylases / Q000235:genetics / Q000378:metabolism; D065637:Cytochrome P-450 CYP2A6; D020345:Enterocolitis, Necrotizing / Q000139:chemically induced* / Q000150:complications; D017809:Fatal Outcome; D006801:Humans; D008297:Male; D006899:Mixed Function Oxygenases / Q000235:genetics / Q000378:metabolism; D009102:Multiple Organ Failure / Q000209:etiology*; D020641:Polymorphism, Single Nucleotide; D018805:Sepsis / Q000150:complications / Q000209:etiology*; D012811:Sigmoid Neoplasms / Q000188:drug therapy*; D005641:Tegafur / Q000008:administration & dosage; D014498:Uracil / Q000008:administration & dosage
chemical_list: D005641:Tegafur; D014498:Uracil; D006899:Mixed Function Oxygenases; D001189:Aryl Hydrocarbon Hydroxylases; D065637:Cytochrome P-450 CYP2A6