The environment and antiphospholipid syndrome.
The etiology of autoimmune diseases is multifactorial. The degree to which genetic and environmental factors influence susceptibility to autoimmune diseases is poorly defined. It is believed that versatile clinical presentations of autoimmune diseases stem from various combinations of the genetic and environmental factors. One of the newly diagnosed autoimmune diseases is the antiphospholipid syndrome (APS). APS is characterized by vascular thrombosis, and/or pregnancy morbidity associated with anticardiolipin (aCL), anti-beta2-glycoprotein-I (anti-beta2GPI) and lupus anticoagulant (LAC).
Levy
Y
Y
Department of Medicine 'E', Meir Medical Center, Sheba Medical Center, Israel.
Almog
O
O
Gorshtein
A
A
Shoenfeld
Y
Y
D017152:Antibodies, Antiphospholipid / Q000187:drug effects / Q000276:immunology; D016736:Antiphospholipid Syndrome / Q000209:etiology* / Q000276:immunology; D001424:Bacterial Infections / Q000150:complications / Q000276:immunology; D001428:Bacterial Vaccines / Q000009:adverse effects; D004342:Drug Hypersensitivity / Q000150:complications / Q000276:immunology; D004777:Environment; D018876:Environmental Illness / Q000150:complications* / Q000276:immunology; D006801:Humans; D018454:Spouses; D014765:Viral Vaccines / Q000009:adverse effects; D014777:Virus Diseases / Q000150:complications / Q000276:immunology; D014947:Wounds and Injuries / Q000150:complications / Q000276:immunology
D017152:Antibodies, Antiphospholipid; D001428:Bacterial Vaccines; D014765:Viral Vaccines