title: Dynamics and thermodynamics of dimerization of parallel G-quadruplexed DNA through pi-pi stacking interaction.
abstract: DNA fragments of d(TTAG(n)) (n = 3-5) form all-parallel G-quadruplexed structure in the presence of K+. We found that G-quadruplexed d(TTAG(n)) forms dimer through end-to-end stacking of the 3'-terminal G-tetrads. In this study, we report the structure of the dimer, and the dynamics and thermodynamics of the dimerization.
authors.affiliation: Department of Chemistry, University of Tsukuba, Tsukuba 305-8571, Japan.
authors.forename: Yoshitake
authors.initials: Y
authors.lastname: Kato
authors.forename: Takako
authors.initials: T
authors.lastname: Ohyama
authors.forename: Shigenori
authors.initials: S
authors.lastname: Nagatomo
authors.forename: Hajime
authors.initials: H
authors.lastname: Mita
authors.forename: Yasuhiko
authors.initials: Y
authors.lastname: Yamamoto
mesh_terms: D004247:DNA / Q000737:chemistry*; D019281:Dimerization; D054856:G-Quadruplexes; D006147:Guanine / Q000737:chemistry; D006801:Humans; D019906:Nuclear Magnetic Resonance, Biomolecular; D009690:Nucleic Acid Conformation; D016615:Telomere / Q000737:chemistry*; D013816:Thermodynamics
chemical_list: D006147:Guanine; D004247:DNA