MPO-ANCA-positive Wegener's granulomatosis presenting with hypertrophic cranial pachymeningitis: case report and review of the literature.
We describe a case of hypertrophic cranial pachymeningitis (HCP) associated with Wegener's granulomatosis (WG) in a 60-year-old man presenting with chronic headache and multiple cranial nerve neuropathies. A test for antibodies to the neutrophil cytoplasmic protein myeloperoxidase (MPO-ANCA) was positive in this case. We review the literature on perinuclear (p)-ANCA-related HCP, including our case. This case indicates the link between MPO-ANCA-positive WG and HCP.
Akahoshi
Mitsuteru
M
Department of Medicine and Biosystemic Science, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan.
Yoshimoto
Goichi
G
Nakashima
Hitoshi
H
Miyake
Katsuhisa
K
Inoue
Yasushi
Y
Tanaka
Yosuke
Y
Tsukamoto
Hiroshi
H
Horiuchi
Takahiko
T
Otsuka
Takeshi
T
Harada
Mine
M