[Fluorescence in situ hybridization in diagnosis of urinary bladder cancer].
The paper presents preliminary results of a study of the diagnosis of urinary bladder cancer by fluorescence in situ hybridization (FISH). Specific chromosomal aberrations are shown to be detectable in both proper tumor tissue and urine from patients with urinary bladder cancer; and the pattern of these changes coincides. FISH may identify cells with genetic disorders in urine long before the clinical symptoms of a recurrence occur.
Stroganova
A M
AM
Khachaturian
A V
AV
D002295:Carcinoma, Transitional Cell / Q000175:diagnosis* / Q000473:pathology; D002869:Chromosome Aberrations; D002886:Chromosomes, Human, Pair 17; D002893:Chromosomes, Human, Pair 3; D002897:Chromosomes, Human, Pair 7; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D008297:Male; D008875:Middle Aged; D001749:Urinary Bladder Neoplasms / Q000175:diagnosis* / Q000473:pathology