Proposed standard nomenclature for the alpha- and beta-globin gene families.
The globin family of genes and proteins has been a recurrent object of study for many decades. This interest has generated a vast amount of knowledge. However it has also created an inconsistent and confusing nomenclature, due to the lack of a systematic approach to naming genes and failure to reflect the phylogenetic relationships among genes of the gene family. To alleviate the problems with the existing system, here we propose a standardized nomenclature for the alpha and beta globin family of genes, based on a phylogenetic analysis of vertebrate alpha and beta globins, and following the Guidelines for Human Gene Nomenclature.
Aguileta
Gabriela
G
Department of Biology, University College London, London, England. gabriela.aguileta@lcb.uu.se
Bielawski
Joseph P
JP
Yang
Ziheng
Z
D000818:Animals; D005914:Globins / Q000235:genetics*; D006801:Humans; D005810:Multigene Family; D009626:Terminology as Topic
D005914:Globins