Stroke associated with diabetes among Canadians: sex and age differences.
OBJECTIVE
To determine the age and sex variations in the relationship between diabetes and stroke.


METHODS
This analysis was based on data from 61,327 Canadians > or =45 years of age who participated in the Canadian Community Health Survey in 2000-2001. Logistic regression analysis was conducted to evaluate the association between diabetes and stroke, and effect modification by age and sex.


RESULTS
The association between diabetes and stroke was stronger in the 45- to 64-year age group than the > or =65 year age group in men but not in women. The increased risk of stroke associated with diabetes was much stronger in men (adjusted OR = 3.86, 95% CI = 2.44-6.13) than in women (adjusted OR = 1.63, 95% CI = 0.88-2.99), and this difference was only observed in the younger age group. The results were similar after further adjustment for hypertension and heart disease.


CONCLUSIONS
There is a stronger association between stroke and diabetes in men than in women 45-64 years of age, suggesting men are more susceptible to stroke than women when they have diabetes.
Lin
Mei
M
Department of Epidemiology and Community Medicine, Faculty of Medicine, University of Ottawa, Ottawa, Canada.
Chen
Yue
Y
Sigal
Ronald J
RJ
D017677:Age Distribution; D000368:Aged; D002170:Canada / Q000453:epidemiology; D048909:Diabetes Complications / Q000453:epidemiology*; D005260:Female; D006306:Health Surveys; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012307:Risk Factors; D017678:Sex Distribution; D020521:Stroke / Q000453:epidemiology*