title: [The extended lymphadenectomy in the treatment of gastric cancer].
abstract: BACKGROUND
  The only potentially curative modality of localized gastric cancer is surgery. However there is area of disagreement among surgeons with respect to the appropriate extent of lymphadenectomy.
  
  
  METHODS
  The retrospective study of a personal experience on 155 patients with gastric cancer; the patients were divided in two groups with respect to the extent of lymphadenectomy.
  
  
  RESULTS
  The results of this study highlight the more effectiveness of D2 resection compared with D1 resection with respect to 5th year survival.
  
  
  CONCLUSIONS
  The goal of treatment is to reduce the risk of recurrent disease. There is considerable debate as to whether the routine use of an extensive en-bloc resection of second echelon lymph nodes (D-2 resection) is superior to a more limited lymphadenectomy of the perigastric lymph nodes (D-1 resection). Therefore the survival benefit of D2 dissection appears to be limited to N2 disease.
  
  
  CONCLUSIONS
  Since nodal status prediction before or during surgery is inaccurate, all patients with curable disease, including those with N0 or NI disease, should undergone extensive node dissection.
authors.affiliation: Università degli Studi di Napoli Federico II, Dipartimento di Scienze Chirurgiche Ortopediche Traumatologiche ed Emergenze, Area Funzionale di Chirurgia Generale, Napoli.
authors.forename: Francesco
authors.initials: F
authors.lastname: Milone
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Salvatore
authors.forename: Ciro
authors.initials: C
authors.lastname: De Martino
authors.forename: Marco
authors.initials: M
authors.lastname: Milone
authors.forename: Luigi Sossio
authors.initials: LS
authors.lastname: Pezzullo
authors.forename: Martina
authors.initials: M
authors.lastname: Pezzullo
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D008197:Lymph Node Excision / Q000379:methods*; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D013274:Stomach Neoplasms / Q000473:pathology / Q000601:surgery*