[Evidence for treating hypertension in stroke prevention].
Hypertension represents a relative risk of stroke up to 5 times. It is associated to ischaemic and haemorrhagic stroke. Hypertension produces an increase in brain vessels resistance and loss of the physiological mechanism of autoregulation, and it can be measured with transcranial doppler. Clinical trials have established that reducing blood pressure is effective in primary prevention of ischaemic and haemorrhagic stroke in hypertensive patients and in secondary prevention in hypertensive and non-hypertensive patients, even with small reductions in blood pressure. There is no evidence of superiority of a definite drug, although drugs that have proven efficacy in clinical trials are recommended in clinical practice.
Serna Candel
Carmen
C
Servicio de Neurología, Hospital General Universitario de Alicante, Alicante, España. serna_car@gva.es
Moreno Pérez
Oscar
O
Moltó Jordà
José Manuel
JM
D000959:Antihypertensive Agents / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D006801:Humans; D006973:Hypertension / Q000188:drug therapy* / Q000503:physiopathology; D020521:Stroke / Q000209:etiology / Q000517:prevention & control*
D000959:Antihypertensive Agents