title: Evaluation of cryptococcus laurentii meningitis in a patient with HIV infection: a case report and review of the literature.
abstract: Cryptococcus neoformans is the most common cryptococci causing infection in humans. Non-neoformans cryptococci have generally been regarded as saprophytes and rarely reported as human pathogens. We report a probable case of Cryptococcus laurentii meningitis in a HIV-infected patient and reviewed the literature on risk factors and treatment of this infection in humans. This patient was successfully treated with amphotericin B followed by fluconazole. Awareness of the emerging antifungal-resistant C. laurentii strains, as reported in the literature, should be emphasized, especially in immunocompromised patients.
authors.affiliation: Department of Medicine, John A. Burns School of Medicine, University of Hawaii, 1356 Lusitana Street, 7th Fl, Honolulu, HI 96813, USA. thanak30@yahoo.com
authors.forename: Thana
authors.initials: T
authors.lastname: Khawcharoenporn
authors.forename: Anucha
authors.initials: A
authors.lastname: Apisarnthanarak
authors.forename: Pattarachai
authors.initials: P
authors.lastname: Kiratisin
authors.forename: Linda M
authors.initials: LM
authors.lastname: Mundy
authors.forename: Thomas C
authors.initials: TC
authors.lastname: Bailey
mesh_terms: D017088:AIDS-Related Opportunistic Infections; D000328:Adult; D003454:Cryptococcus / Q000302:isolation & purification*; D015658:HIV Infections / Q000150:complications / Q000175:diagnosis*; D006801:Humans; D008297:Male; D016919:Meningitis, Cryptococcal / Q000175:diagnosis* / Q000209:etiology