Application of ionic liquids in the microwave-assisted extraction of trans-resveratrol from Rhizma Polygoni Cuspidati.
In this paper, the application of 1-n-butyl -3-methylimidazolium-based ionic liquids aqueous solutions as solvents in the microwave-assisted extraction (MAE) technique was first developed for the extraction of trans-resveratrol from Rhizma Polygoni Cuspidati. 1-butyl-3-methylimidazolium bromide ([bmim]Br) solution was selected as solvent; the conditions of MAE including the size of sample, liquid/solid ratio, extraction temperature and time were optimized by means of an orthogonal design L(9)(3(4)). Under optimized conditions, the extraction yield value of trans-resveratrol was 92.8% in a one-step extraction. The recovery was in the range 93.7-103.2% with relative standard deviation lower than 3.0% by the proposed procedure. The method was applied to extract trans-resveratrol from several different region samples. On the basis of extraction solvent and time, the proposed extraction technique was a green, rapid and alternative technique to extract and analyze trans-resveratrol in Rhizma Polygoni Cuspidati samples.
Du
Fu-You
FY
School of Chemistry and Chemical Engineering, Sun Yat-Sen University, Guangzhou, Guangdong 510275, China.
Xiao
Xiao-Hua
XH
Li
Gong-Ke
GK
D001881:Borates / Q000737:chemistry; D005591:Chemical Fractionation / Q000379:methods; D002851:Chromatography, High Pressure Liquid / Q000379:methods; D045468:Fallopia japonica / Q000737:chemistry*; D007093:Imidazoles / Q000737:chemistry; D008872:Microwaves; D000077185:Resveratrol; D012997:Solvents / Q000737:chemistry; D013267:Stilbenes / Q000302:isolation & purification*
C419324:1-butyl-3-methylimidazolium tetrafluoroborate; D001881:Borates; D007093:Imidazoles; D012997:Solvents; D013267:Stilbenes; C502841:1-butyl-3-methylimidazolium chloride; D000077185:Resveratrol