title: Molecular design of novel spin-labeled nucleosides directly attached base moiety.
abstract: N-tert-Butylaminoxyl nucleosides (1 and 2) were synthesized starting from 6-chloropurine derivative (3). These compounds are expected as a new tool to elucidate structure of DNA. Their properties and pH-dependent change of EPR spectra were studied.
authors.affiliation: Graduate School of Pharmaceutical Sciences, Kyushu Univerisity, Maidashi, Higashi-ku, Fukuoka 812-8582, Japan.
authors.forename: Toshiyuki
authors.initials: T
authors.lastname: Kaneko
authors.forename: Toshinori
authors.initials: T
authors.lastname: Katsurabara
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Matsui
authors.forename: Mariko
authors.initials: M
authors.lastname: Aso
authors.forename: Noboru
authors.initials: N
authors.lastname: Koga
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Suemune
mesh_terms: D004578:Electron Spin Resonance Spectroscopy; D006863:Hydrogen-Ion Concentration; D009705:Nucleosides / Q000138:chemical synthesis* / Q000737:chemistry*; D011687:Purines / Q000737:chemistry*; D011743:Pyrimidines / Q000737:chemistry*; D013113:Spin Labels / Q000138:chemical synthesis*
chemical_list: D009705:Nucleosides; D011687:Purines; D011743:Pyrimidines; D013113:Spin Labels