title: Salmonella typhimurium meningitis in an adult patient with AIDS.
abstract: Salmonella meningitis is an unusual complication of Salmonella sepsis and occurs mainly in children. A rare case of Salmonella typhimurium meningitis occurring in an adult HIV positive man who presented with a history of fever and diarrhoea is reported. On examination he was dehydrated, and had oral thrush, weakness of lower limbs and neck stiffness. A septic diagnostic screen was performed and he was commenced on empiric intravenous cefotaxime therapy for meningitis. S typhimurium was cultured from cerebrospinal fluid and blood culture specimens. It was non-lactose fermenting, oxidase negative, H(2)S positive and motile. Cefotaxime was continued for 14 days and the patient responded without neurological sequelae.
authors.affiliation: Department of Microbiological Pathology, Medunsa Campus, University of Limpopo, and the National Health Laboratory Services, Pretoria, South Africa.
authors.forename: K Swe
authors.initials: KS
authors.lastname: Swe
authors.forename: G
authors.initials: G
authors.lastname: Nagel
authors.forename: M
authors.initials: M
authors.lastname: Van der Westhuizen
authors.forename: A A
authors.initials: AA
authors.lastname: Hoosen
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000175:diagnosis* / Q000188:drug therapy; D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002439:Cefotaxime / Q000627:therapeutic use; D006801:Humans; D008297:Male; D016920:Meningitis, Bacterial / Q000175:diagnosis* / Q000188:drug therapy; D012480:Salmonella Infections / Q000175:diagnosis* / Q000188:drug therapy; D012486:Salmonella typhimurium
chemical_list: D000900:Anti-Bacterial Agents; D002439:Cefotaxime