[Genotyping of Yersinia pseudotuberculosis isolated in Siberia and Far East].
Genotypic characteristics based three main factors of pathogenicity (presence of resident plasmids [pYV, pVM], gene of toxin-superantigen ypm and nine genes for high pathogenicity island [HPI]) of 212 strains of Y. pseudotuberculosis isolated in Siberia and Far East were studied. It was shown that strains of Y. pseudotuberculosis with one of two variants of plasmids 82:47 MDa and 47 MDa (60.8% and 31.6% respectively) are predominated. Gene ypmA was detected in 96.2% of isolated strains. Eight strains had none of the ymp gene variants. HPI were detected in 96.2% of isolated strains. Obtained characteristics of Y. pseudotuberculosis allowed to determine the dominating genogroup pWYV+, ypmA+, HPI- (95.8% of strains) that cause systemic infection.
Chesnokova
M V
MV
Klimov
V T
VT
Maramovich
A S
AS
D000818:Animals; D001426:Bacterial Proteins / Q000235:genetics; D004783:Environmental Microbiology; D044404:Genomic Islands / Q000235:genetics; D006801:Humans; D017720:Molecular Epidemiology; D010957:Plasmids / Q000235:genetics; D012377:Rodentia / Q000382:microbiology; D012800:Siberia / Q000453:epidemiology; D013045:Species Specificity; D018089:Superantigens / Q000235:genetics; D037521:Virulence Factors / Q000235:genetics; D015011:Yersinia pseudotuberculosis / Q000145:classification / Q000235:genetics*; D015012:Yersinia pseudotuberculosis Infections / Q000453:epidemiology*
D001426:Bacterial Proteins; D018089:Superantigens; D037521:Virulence Factors; C093313:Yersinia pseudotuberculosis-derived mitogen