Synthesis of a peptide nucleic acid oligomer with pyrimido[4,5-d]pyrimidine-2,4,5,7-(1H,3H,6H,8H)-tetraone as a nucleobase.
A peptide nucleic acid (PNA) oligomer containing pyrimido[4,5-d]pyrimidine-2,4,5,7-(1H,3H,6H,8H)-tetraone (PPT) as a nucleobase, which is expected to serve as a universal base, was synthesized.
Kataoka
Masanori
M
Research Center for Computational Science, National Institutes for Natural Sciences, Okazaki 444-8787, Japan.
Hirano
Taisuke
T
Kuroda
Kenji
K
Hayakawa
Yoshihiro
Y
D002851:Chromatography, High Pressure Liquid; D020135:Peptide Nucleic Acids / Q000138:chemical synthesis* / Q000737:chemistry; D011744:Pyrimidinones / Q000737:chemistry*
D020135:Peptide Nucleic Acids; D011744:Pyrimidinones; C520194:pyrimido(4,5-d)pyrimidine-2,4,5,7-(1H,3H,6H,8H)-tetraone