title: [Preventive efficacy of propafenone, its effect on functional state of the heart during long-term treatment of patients with paroxysmal atrioventricular arrhythmias].
abstract: Efficacy and tolerability of propafenone were studied in the process of long-term treatment of patients with various forms of paroxysmal atrioventricular arrhythmias. It was established that propafenone appears to be highly effective remedy for prophylaxis of paroxysms of atrioventricular reciprocal nodal tachycardia and atrioventricular tachycardia in Wolf-Parkinson-White syndrome. The preparation did not exert negative influence on functional state of the heart. Side reactions requiring withdrawal of propafenone were observed in 12.7% of cases.
authors.forename: K M
authors.initials: KM
authors.lastname: Koshumbaeva
authors.forename: I N
authors.initials: IN
authors.lastname: Belokopit
authors.forename: D I
authors.initials: DI
authors.lastname: Makhanov
authors.forename: M N
authors.initials: MN
authors.lastname: Nugmanova
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000889:Anti-Arrhythmia Agents / Q000627:therapeutic use*; D004562:Electrocardiography / Q000187:drug effects; D005260:Female; D005500:Follow-Up Studies; D006321:Heart / Q000187:drug effects*; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D008297:Male; D008875:Middle Aged; D011405:Propafenone / Q000627:therapeutic use*; D013611:Tachycardia, Atrioventricular Nodal Reentry / Q000503:physiopathology / Q000517:prevention & control*; D013614:Tachycardia, Paroxysmal / Q000150:complications / Q000503:physiopathology / Q000517:prevention & control*; D013997:Time Factors; D016896:Treatment Outcome; D014927:Wolff-Parkinson-White Syndrome / Q000150:complications / Q000503:physiopathology / Q000517:prevention & control
chemical_list: D000889:Anti-Arrhythmia Agents; D011405:Propafenone