Fetal intravenous immunoglobulin therapy in rhesus hemolytic disease.
Intrauterine blood transfusion is the mainstay of treatment of fetal rhesus hemolytic anemia with optimal perinatal outcome. Postnatal immunoglobulin therapy has been successfully used in the management of alloimmunized neonates and has shown to decrease the need for exchange transfusion. We report the first case series of fetal immunoglobulin therapy in the antenatal management of severe Rh incompatibility.
Kriplani
Alka
A
Department of Obstetrics and Gynecology, All India Institute of Medical Sciences, New Delhi, India.
Malhotra Singh
Bhawna
B
Mandal
Kavita
K
D000328:Adult; D000743:Anemia, Hemolytic / Q000276:immunology* / Q000628:therapy*; D001805:Blood Transfusion, Intrauterine / Q000379:methods*; D005260:Female; D005315:Fetal Diseases / Q000276:immunology / Q000628:therapy*; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use*; D007231:Infant, Newborn; D007518:Isoantibodies / Q000097:blood / Q000276:immunology*; D011247:Pregnancy; D011248:Pregnancy Complications; D011256:Pregnancy Outcome; D012203:Rh Isoimmunization / Q000276:immunology / Q000628:therapy*; D016896:Treatment Outcome
D016756:Immunoglobulins, Intravenous; D007518:Isoantibodies