title: [Effect of genetic polymorphism of cytochrome P450 3A and transporter gene on pharmacokinetics of tacrolimus, a calcineurin inhibitor].
authors.affiliation: toshiro.niwa@jp.astellas.com
authors.forename: Toshiro
authors.initials: T
authors.lastname: Niwa
authors.forename: Toshifumi
authors.initials: T
authors.lastname: Shiraga
authors.forename: Minoru
authors.initials: M
authors.lastname: Omura
authors.forename: Toshihiko
authors.initials: T
authors.lastname: Kondo
authors.forename: Masatoshi
authors.initials: M
authors.lastname: Kuroda
authors.forename: Akira
authors.initials: A
authors.lastname: Takagi
mesh_terms: D020168:ATP Binding Cassette Transporter, Subfamily B, Member 1 / Q000235:genetics*; D051544:Cytochrome P-450 CYP3A; D003577:Cytochrome P-450 Enzyme System / Q000235:genetics*; D006801:Humans; D007166:Immunosuppressive Agents / Q000493:pharmacokinetics*; D011110:Polymorphism, Genetic; D016559:Tacrolimus / Q000493:pharmacokinetics*
chemical_list: D020168:ATP Binding Cassette Transporter, Subfamily B, Member 1; D007166:Immunosuppressive Agents; D003577:Cytochrome P-450 Enzyme System; C510164:CYP3A5 protein, human; D051544:Cytochrome P-450 CYP3A; C510163:CYP3A4 protein, human; D016559:Tacrolimus