title: [Evaluation of antibacterial activity of apex-phoresis].
abstract: Effects of apex-phoresis on dental root canal microflora were studied and optimal dosage parameters were determined. Microbiological study in vitro has established that optimal antibacterial effect was achieved with the apex-phoresis dosage in the range between 2.5-5 mA/min. Study of the effects of apex-phoresis on dental root canal microflora in vivo disclosed its high antibacterial activity both in cases of pulpitis and destructive forms of chronic periodontitis. For the first time the data are confirmed by molecular-genetic method of detection of hard to cultivate virulent anaerobic bacteria. The results of the study allow to recommend apex-phoresis for wide use in clinical practice as an effective way to sterilize difficult to traverse dental root canals.
authors.forename: O I
authors.initials: OI
authors.lastname: Efanov
authors.forename: V N
authors.initials: VN
authors.lastname: Tsarev
authors.forename: A G
authors.initials: AG
authors.lastname: Volkov
authors.forename: E N
authors.initials: EN
authors.lastname: Nikolaeva
authors.forename: N Zh
authors.initials: NZh
authors.lastname: Dikopova
authors.forename: A S
authors.initials: AS
authors.lastname: Nosik
mesh_terms: D000293:Adolescent; D000328:Adult; D001421:Bacteria, Anaerobic / Q000187:drug effects / Q000302:isolation & purification; D001431:Bacteriological Techniques; D002908:Chronic Disease; D003627:Data Interpretation, Statistical; D003786:Dental Pulp Cavity / Q000382:microbiology*; D005500:Follow-Up Studies; D006801:Humans; D007478:Iontophoresis; D008875:Middle Aged; D010518:Periodontitis / Q000175:diagnosis / Q000188:drug therapy* / Q000382:microbiology; D011671:Pulpitis / Q000175:diagnosis / Q000188:drug therapy* / Q000382:microbiology; D012388:Root Canal Irrigants / Q000008:administration & dosage* / Q000494:pharmacology; D013997:Time Factors; D019227:Tooth Apex; D016896:Treatment Outcome
chemical_list: D012388:Root Canal Irrigants