Highly enantioselective transfer hydrogenation of fluoroalkyl ketones.
[Structure: see text] The asymmetric transfer hydrogenation of fluoroalkyl ketones mediated by [Ru(eta6-arene)((S,S)-R2NSO2DPEN)] catalysts using HCO2H-Et3N afforded the corresponding alcohols with high ee's and in excellent yields.
Sterk
Damjan
D
Laboratory of Organic and Medicinal Chemistry, National Institute of Chemistry, Hajdrihova 19, SI-1001 Ljubljana, Slovenia.
Stephan
Michel
M
Mohar
Barbara
B
D006859:Hydrogen / Q000737:chemistry*; D007659:Ketones / Q000737:chemistry*; D013237:Stereoisomerism
D007659:Ketones; D006859:Hydrogen