[Polyethox corrects hemodynamic and hemorrheological disturbances after infusion-transfusion therapy of massive hemorrhage].
Inclusion of polyethox, a medicinal form of high-molecular (4,5 x 10(6) Da) poly(ethylene oxide), into infusion-transfusion therapy of massive hemorrhage (33% of blood volume) in cats leads to an increase in the stroke and cardiac indices, restores antiturbulent and hemorrheological properties of blood, increases systemic oxygen transport, and reduces hypoxic acid-base balance disturbances.
Chernysheva
G A
GA
Plotnikov
M B
MB
Smol'iakova
V I
VI
Aliev
O I
OI
D000136:Acid-Base Equilibrium / Q000187:drug effects; D000818:Animals; D001803:Blood Transfusion; D002306:Cardiac Volume / Q000187:drug effects; D002415:Cats; D003131:Combined Modality Therapy; D005260:Female; D006470:Hemorrhage / Q000188:drug therapy* / Q000628:therapy; D008297:Male; D010100:Oxygen / Q000378:metabolism; D011092:Polyethylene Glycols / Q000494:pharmacology / Q000627:therapeutic use*; D013318:Stroke Volume / Q000187:drug effects
D011092:Polyethylene Glycols; D010100:Oxygen