Lactic acid bacteria (LAB) bind to human B- or H-antigens expressed on intestinal mucosa.
Twenty lactobacilli isolated from human feces were studied for binding to the human blood type B-antigen [Galalpha1-3 (Fucalpha1-2) Gal-] and H-antigen (Fucalpha1-2Gal-] expressed sugar chains in human intestinal mucosa. We found two strains, L. gasseri OLL2755 and L. gasseri OLL2877 that firmly adhere to human B-antigen, and we found L. gasseri OLL2827 bound to the H-antigen.
Uchida
Hideaki
H
Laboratory of Animal Products Chemistry, Graduate School of Agricultural Science, Tohoku University. hideaki7@bios.tohoku.ac.jp
Kawai
Yasushi
Y
Kinoshita
Hideki
H
Kitazawa
Haruki
H
Miura
Koh
K
Shiiba
Kenichi
K
Horii
Akira
A
Kimura
Katsunori
K
Taketomo
Naoki
N
Oda
Munehiro
M
Yajima
Takaji
T
Saito
Tadao
T
D001422:Bacterial Adhesion; D001789:Blood Group Antigens / Q000276:immunology*; D006801:Humans; D007413:Intestinal Mucosa / Q000276:immunology*; D007778:Lactobacillus / Q000502:physiology*
D001789:Blood Group Antigens