title: Deep cerebral vein thrombosis associated with iron deficiency anaemia in adults.
abstract: Cerebral venous thrombosis (CVT) is rare and has a wide spectrum of symptoms, therefore it is difficult to diagnose. Thrombosis of the deep cerebral veins occurs very rarely: it has been reported that approximately 6% of patients with CVT have deep CVT, and the prognosis for patients with this condition is poor. CVT has been reported in association with dehydration, a hypercoagulable state, mastoiditis, tumour invasion of a venous sinus, use of oral contraceptives, pregnancy, puerperium, head trauma, vasculitis, and intracranial and systemic infections. However, in the literature, there are few reported cases of CVT in association with iron deficiency anaemia, especially in adults. We present here two patients with bilateral thalamic and basal ganglionic lesions due to thrombosis of the deep cerebral veins. Both of our patients had severe hypochromic microcytic anaemia due to iron deficiency, and both had a good prognosis after 2 months.
authors.affiliation: Department of Neurology, Faculty of Medicine, University of Trakya, Edirne 22030, Turkey.
authors.forename: Kemal
authors.initials: K
authors.lastname: Balci
authors.forename: Ufuk
authors.initials: U
authors.lastname: Utku
authors.forename: Talip
authors.initials: T
authors.lastname: Asil
authors.forename: Nilüfer
authors.initials: N
authors.lastname: Büyükkoyuncu
mesh_terms: D000293:Adolescent; D000328:Adult; D018798:Anemia, Iron-Deficiency / Q000150:complications* / Q000628:therapy; D000925:Anticoagulants / Q000627:therapeutic use; D001479:Basal Ganglia / Q000098:blood supply / Q000473:pathology; D016913:Blood Component Transfusion; D002550:Cerebral Veins / Q000473:pathology*; D004912:Erythrocytes / Q000473:pathology; D005260:Female; D006495:Heparin, Low-Molecular-Weight / Q000627:therapeutic use; D006801:Humans; D020767:Intracranial Thrombosis / Q000150:complications* / Q000188:drug therapy; D013788:Thalamus / Q000098:blood supply / Q000473:pathology; D016896:Treatment Outcome; D020246:Venous Thrombosis / Q000150:complications* / Q000188:drug therapy; D014859:Warfarin / Q000627:therapeutic use
chemical_list: D000925:Anticoagulants; D006495:Heparin, Low-Molecular-Weight; D014859:Warfarin