title: Organocatalytic asymmetric michael addition of aldehydes to beta-nitroacroleine dimethyl acetal.
abstract: [Structure: see text] The organocatalytic asymmetric Michael addition of aldehydes to beta-nitroacroleine dimethyl acetal has been studied in detail. The reaction took place with excellent yields and high stereoselectivities when a chiral beta-amino alcohol such as L-prolinol was employed as the catalyst, leaving a formation of highly functionalized enantioenriched compounds containing two differentiated formyl groups together with a nitro moiety.
authors.affiliation: Department of Organic Chemistry II, Faculty of Science and Technology, University of the Basque Country, P.O. Box 644, 48080 Bilbao, Spain.
authors.forename: Efraim
authors.initials: E
authors.lastname: Reyes
authors.forename: Jose L
authors.initials: JL
authors.lastname: Vicario
authors.forename: Dolores
authors.initials: D
authors.lastname: Badía
authors.forename: Luisa
authors.initials: L
authors.lastname: Carrillo