title: Cellular reprogramming.
abstract: The concept of reprogramming a cell is very intriguing and has immense therapeutic potential. Examples from physiology and developmental biology suggest that it may well be possible. Experimental approaches are beginning to suggest this also, in particular the initially astonishing accomplishment of somatic cell nuclear transfer and cloning. This chapter reviews current strategies and describes emerging methods for the proposition of reprogramming cells with cell extracts.
authors.affiliation: Molecular and Cell Biology, Advanced Cell Technology, Inc., Worcester, Massachusetts, USA.
authors.forename: Sadhana
authors.initials: S
authors.lastname: Agarwal
mesh_terms: D000818:Animals; D001426:Bacterial Proteins / Q000378:metabolism / Q000494:pharmacology; D002457:Cell Extracts / Q000302:isolation & purification; D002463:Cell Membrane Permeability; D065150:Cellular Reprogramming; D006801:Humans; D013234:Stem Cells / Q000187:drug effects; D013301:Streptolysins / Q000378:metabolism / Q000494:pharmacology
chemical_list: D001426:Bacterial Proteins; D002457:Cell Extracts; D013301:Streptolysins; C025964:streptolysin O