title: Radiopharmaceutical diagnosis of Erdheim-Chester's disease.
abstract: Erdheim-Chester's disease is a non-inherited multi-focal lipid-storing histiocytosis of unknown origin without a complete and convincing diagnostic and therapeutic protocol. We have previously suggested diagnostic methods using radioisotopes to evaluate this disseminating disease, but they are neither specific nor selective in this regard. The present hypothesis-driven paper reviewing our case proposes novel approaches involving nuclear medicine and utilizing radiopharmaceuticals to identify this potentially fatal multi-system disease.
authors.affiliation: Division of Cardiac Center for Cardiology Department of Psychiatry, Asklepios-Med Bt., H-6722 Szeged, Kossuth Lajos sgt. 23, Hungary. palotas@nepsy.szote.u-szeged.hu
authors.forename: András
authors.initials: A
authors.lastname: Palotás
authors.forename: Gábor
authors.initials: G
authors.lastname: Bogáts
authors.forename: Máté
authors.initials: M
authors.lastname: Lázár
authors.forename: Miklós
authors.initials: M
authors.lastname: Papós
authors.forename: Keyvan
authors.initials: K
authors.lastname: Matin
authors.forename: László
authors.initials: L
authors.lastname: Pávics
mesh_terms: D001842:Bone and Bones / Q000000981:diagnostic imaging; D031249:Erdheim-Chester Disease / Q000175:diagnosis* / Q000000981:diagnostic imaging*; D006098:Granulocytes / Q000378:metabolism; D006801:Humans; D008297:Male; D008875:Middle Aged; D009943:Organophosphorus Compounds / Q000494:pharmacology; D015609:Organotechnetium Compounds / Q000494:pharmacology; D019275:Radiopharmaceuticals; D015899:Tomography, Emission-Computed, Single-Photon / Q000379:methods; D051598:Whole Body Imaging
chemical_list: D009943:Organophosphorus Compounds; D015609:Organotechnetium Compounds; D019275:Radiopharmaceuticals; C078700:technetium tc-99m tetrofosmin