[Production of granulocyte colony-stimulating factor and parathyroid hormone-related protein in squamous cell carcinoma of the renal pelvis accompanied with inferior vena cava thrombus].
A 54-year-old man with general fatigue and lumbago was admitted for further examination of hypercalcemia and leukocytosis. CT showed a huge renal tumor and extension of the tumor thrombus to the inferior vena cava (IVC). Moreover, the serum granulocyte colony-stimulating factor (G-CSF) and the C-terminal of parathyroid hormone-related protein (PTHrP) were elevated. Under the diagnosis of advanced renal tumor, we performed nephro-ureterectomy and throbectomy. Pathological examination revealed squamous cell carcinoma of the renal pelvis. To our knowledge, this is the first case in Japan that of the simultaneous production of G-CSF and PTHrP in squamous cell carcinoma of the renal pelvis accompanied with IVC thrombus.
Nemoto
Kaoru
K
Department of Urology, Kitamurayama Public Hospital.
Matsuzawa
Ichiro
I
Kimura
Go
G
Nishimura
Taiji
T
D002294:Carcinoma, Squamous Cell / Q000150:complications / Q000378:metabolism* / Q000601:surgery; D016179:Granulocyte Colony-Stimulating Factor / Q000096:biosynthesis*; D006801:Humans; D007680:Kidney Neoplasms / Q000150:complications / Q000378:metabolism* / Q000601:surgery; D007682:Kidney Pelvis; D008297:Male; D008875:Middle Aged; D009392:Nephrectomy; D010257:Paraneoplastic Syndromes; D044162:Parathyroid Hormone-Related Protein / Q000096:biosynthesis*; D017131:Thrombectomy; D013927:Thrombosis / Q000150:complications / Q000601:surgery*; D014682:Vena Cava, Inferior
D044162:Parathyroid Hormone-Related Protein; D016179:Granulocyte Colony-Stimulating Factor