title: Sildenafil 20 mg. Pulmonary arterial hypertension: for oral treatment, no better than bosentan.
abstract: For oral treatment of pulmonary arterial hypertension there is no firm evidence that sildenafil is more effective or better tolerated than bosentan, which remains the better option for oral treatment before resorting to intravenous epoprostenol.
mesh_terms: D002986:Clinical Trials as Topic; D017277:Drug Approval; D005602:France; D006801:Humans; D006976:Hypertension, Pulmonary / Q000188:drug therapy*; D010726:Phosphodiesterase Inhibitors / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use; D010879:Piperazines / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D011651:Pulmonary Artery / Q000187:drug effects*; D015996:Survival Rate; D014665:Vasodilator Agents / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use
chemical_list: D010726:Phosphodiesterase Inhibitors; D010879:Piperazines; D014665:Vasodilator Agents