Vascular grafts and the endothelium.
This article discusses the importance of the endothelium for successful vascular grafts derived from both native arteries and synthetic materials. It also discusses the fundamental strategies to endothelialize synthetic grafts in animal experiments and in the clinic, as well as the use of endothelial progenitor cells (EPCs), bone marrow-derived cells, and mesothelium as endothelial substitutes.
Hoenig
Michel R
MR
Centre for Research in Vascular Biology, Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, Brisbane, Australia.
Campbell
Gordon R
GR
Campbell
Julie H
JH
D000818:Animals; D016026:Bone Marrow Transplantation; D002318:Cardiovascular Diseases / Q000601:surgery*; D042783:Endothelial Cells / Q000378:metabolism; D004730:Endothelium, Vascular / Q000503:physiopathology / Q000637:transplantation*; D004848:Epithelium / Q000378:metabolism; D006801:Humans; D008954:Models, Biological; D013234:Stem Cells / Q000378:metabolism; D013927:Thrombosis / Q000517:prevention & control; D014652:Vascular Diseases / Q000503:physiopathology / Q000601:surgery