title: Deciphering the RNA polymerase II structure: a personal perspective.
abstract: This year's Nobel laureate in chemistry is Roger Kornberg. Patrick Cramer gives a personal account of how the Kornberg laboratory determined the structure of the RNA polymerase II core enzyme.
authors.affiliation: Gene Center Munich, Department of Chemistry and Biochemistry, Ludwig-Maximilians-Universität München, Feodor-Lynen-Strasse 25, D-81377 Munich, Germany. cramer@lmb.uni-muenchen.de
authors.forename: Patrick
authors.initials: P
authors.lastname: Cramer
mesh_terms: D008958:Models, Molecular; D009613:Nobel Prize; D011487:Protein Conformation; D012319:RNA Polymerase II / Q000737:chemistry* / Q000378:metabolism; D014158:Transcription, Genetic / Q000235:genetics
chemical_list: D012319:RNA Polymerase II