title: [Metachronous adrenal metastasis in two patients undergoing radical nephrectomy for primary renal cell carcinoma].
abstract: OBJECTIVE
  We report two exceptional cases of metachronous adrenal metastasis of renal cell carcinomas and perform a bibliographic review. After the evaluation of various features such as frequency, etiopathogenesis, diagnosis and follow-up of these patients we conclude that these metastases are rare, and they usually appear late in the evolution of patients with low stage renal cell carcinoma.
  
  
  CONCLUSIONS
  Once reviewed the treatment and checked the absence of guidelines for the therapeutic management of these patients we propose surgery for the adrenal metastasis as well as adjuvant treatment with immunotherapy.
authors.affiliation: Servio de Urología, Hospital Universitario Virgen de las Nieves, Granada, España. jrosal@fundacionhvn.org
authors.forename: José Luis
authors.initials: JL
authors.lastname: Rosales Leal
authors.forename: Francisco
authors.initials: F
authors.lastname: Rodríguez Herrera
authors.forename: Manuel
authors.initials: M
authors.lastname: Ortiz Gorráiz
authors.forename: Beatriz
authors.initials: B
authors.lastname: Honrubia Vílchez
authors.forename: Antonio
authors.initials: A
authors.lastname: Fernández Sánchez
authors.forename: Fernando
authors.initials: F
authors.lastname: Vázquez Alonso
authors.forename: Manrique
authors.initials: M
authors.lastname: Pascual Geler
authors.forename: Antonio
authors.initials: A
authors.lastname: Martínez Morcillo
authors.forename: Javier
authors.initials: J
authors.lastname: Vicente Prados
authors.forename: José Manuel
authors.initials: JM
authors.lastname: Cózar Olmo
authors.forename: Eduardo
authors.initials: E
authors.lastname: Espejo Maldonado
authors.forename: Miguel
authors.initials: M
authors.lastname: Tallada Buñuel
mesh_terms: D000310:Adrenal Gland Neoplasms / Q000556:secondary*; D000368:Aged; D002292:Carcinoma, Renal Cell / Q000556:secondary* / Q000601:surgery*; D005260:Female; D006801:Humans; D007680:Kidney Neoplasms / Q000473:pathology* / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D009392:Nephrectomy