title: Improved risk adjustment for comparison of surgical site infection rates.
abstract: OBJECTIVE
  To develop prognostic models for improved risk adjustment in surgical site infection surveillance for 5 surgical procedures and to compare these models with the National Nosocomial Infection Surveillance system (NNIS) risk index.
  
  
  METHODS
  In a multicenter cohort study, prospective assessment of surgical site infection and risk factors was performed from 1996 to 2000. In addition, risk factors abstracted from patient files, available in a national medical register, were used. The c-index was used to measure the ability of procedure-specific logistic regression models to predict surgical site infection and to compare these models with models based on the NNIS risk index. A c-index of 0.5 indicates no predictive power, and 1.0 indicates perfect predictive power.
  
  
  METHODS
  Sixty-two acute care hospitals in the Dutch national surveillance network for nosocomial infections.
  
  
  METHODS
  Patients who underwent 1 of 5 procedures for which the predictive ability of the NNIS risk index was moderate: reconstruction of the aorta (n=875), femoropopliteal or femorotibial bypass (n=641), colectomy (n=1,142), primary total hip prosthesis (n=13,770), and cesarean section (n=2,962).
  
  
  RESULTS
  The predictive power of the new model versus the NNIS index was 0.75 versus 0.62 for reconstruction of the aorta (P<.01), 0.78 versus 0.58 for femoropopliteal or femorotibial bypass (P<.001), 0.69 versus 0.62 for colectomy (P<.001), 0.64 versus 0.56 for primary total hip prosthesis arthroplasty (P<.001), and 0.70 versus 0.54 for cesarean section (P<.001).
  
  
  CONCLUSIONS
  Data available from hospital information systems can be used to develop models that are better at predicting the risk of surgical site infection than the NNIS risk index. Additional data collection may be indicated for certain procedures--for example, total hip prosthesis arthroplasty.
authors.affiliation: Department of Infectious Diseases Epidemiology, National Institute of Public Health and the Environment, Bilthoven, The Netherlands.
authors.forename: Eveline L P E
authors.initials: EL
authors.lastname: Geubbels
authors.forename: Diederick E
authors.initials: DE
authors.lastname: Grobbee
authors.forename: Christina M J E
authors.initials: CM
authors.lastname: Vandenbroucke-Grauls
authors.forename: Jan C
authors.initials: JC
authors.lastname: Wille
authors.forename: Annette S
authors.initials: AS
authors.lastname: de Boer
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D015331:Cohort Studies; D005260:Female; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D011159:Population Surveillance / Q000379:methods*; D011237:Predictive Value of Tests; D020379:Risk Adjustment; D013530:Surgical Wound Infection / Q000209:etiology / Q000517:prevention & control*