title: Synthesis of three natural diosgenyl glycosides.
abstract: Three well-known natural diosgenyl glycosides which have the same sugar chains but different sequence, ophipogonin C', polyphillin C and prosapogenin B, were synthesised by a facile approach. A method using the levulinyl group as a protecting group to selectively mask the C3-OH of diosgenyl 4,6-O-benzylidene-beta-D-glucopyranoside is described.
authors.affiliation: Key Laboratory of Bioactive Substance and Resources Utilisation of Chinese Herbal Medicine, Peking Union Medical College, Beijing, 100050, China.
authors.forename: S-J
authors.initials: SJ
authors.lastname: Hou
authors.forename: C-C
authors.initials: CC
authors.lastname: Zou
authors.forename: L
authors.initials: L
authors.lastname: Zhou
authors.forename: P-S
authors.initials: PS
authors.lastname: Lei
authors.forename: D-Q
authors.initials: DQ
authors.lastname: Yu
mesh_terms: D002855:Chromatography, Thin Layer; D004144:Diosgenin / Q000031:analogs & derivatives* / Q000138:chemical synthesis*; D006027:Glycosides / Q000138:chemical synthesis*; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D015394:Molecular Structure
chemical_list: D006027:Glycosides; C517909:ophipogonin C'; C517908:polyphillin C; C517907:prosapogenin B; D004144:Diosgenin