title: Evaluation of left ventricular function with cardiac magnetic resonance imaging using Fourier fitting.
abstract: The aims of this study were to investigate the applicability of Fourier fitting in the magnetic resonance (MR) evaluation of left ventricular (LV) function and to determine the optimal number of harmonics for fitting. Cine cardiac MR imaging was performed in 10 subjects, and an LV time-volume curve was generated. Fourier fitting was applied to the original curve using 1-10 harmonics, and the qualities of the time-volume curve and first-derivative curve were evaluated. LV functional parameters were calculated from curves generated with and without fitting. The quality of the original time-volume curve was good, and Fourier fitting had no substantial effect on functional parameters obtained directly from the time-volume curve such as ejection fraction. The first-derivative curve generated without fitting showed substantial artificial fluctuation. The application of Fourier fitting depressed the fluctuation and tended to decrease estimates of peak ejection rate and peak filling rate. Five or six harmonics appeared to be appropriate for obtaining a high-quality first-derivative curve. In conclusion, Fourier fitting was indicated to aid in reducing the artificial fluctuation of the first-derivative curve generated from cine cardiac MR imaging and to contribute to the evaluation of functional parameters derived from the first-derivative curve.
authors.affiliation: Department of Radiology, Institute of Medical Science, University of Tokyo, and Department of Cardiovascular Medicine, Sanno Hospital, Tokyo 108-8639, Japan.
authors.forename: Yukihiro
authors.initials: Y
authors.lastname: Nomura
authors.forename: Yusuke
authors.initials: Y
authors.lastname: Inoue
authors.forename: Ikuo
authors.initials: I
authors.lastname: Yokoyama
authors.forename: Takashi
authors.initials: T
authors.lastname: Nakaoka
authors.forename: Daisuke
authors.initials: D
authors.lastname: Itoh
authors.forename: Toshiyuki
authors.initials: T
authors.lastname: Okubo
authors.forename: Kuni
authors.initials: K
authors.lastname: Ohtomo
mesh_terms: D000328:Adult; D000970:Antineoplastic Agents / Q000009:adverse effects; D005260:Female; D005583:Fourier Analysis; D006801:Humans; D008232:Lymphoproliferative Disorders / Q000188:drug therapy / Q000473:pathology / Q000503:physiopathology*; D019028:Magnetic Resonance Imaging, Cine / Q000379:methods*; D008297:Male; D008875:Middle Aged; D018487:Ventricular Dysfunction, Left / Q000139:chemically induced / Q000175:diagnosis*; D016277:Ventricular Function, Left
chemical_list: D000970:Antineoplastic Agents