title: Over-diagnosis of malaria is not a lost cause.
abstract: BACKGROUND
  Recent studies have highlighted the over-diagnosis of malaria in clinical settings in Africa. This study assessed the impact of a training programme implemented as part of an intervention trial on diagnostic behaviour of clinicians in a rural district hospital in a low-moderate malaria transmission setting.
  
  
  METHODS
  From the beginning of 2005, a randomized controlled trial (RCT) of intermittent preventive treatment for malaria in infants (IPTi) has been conducted at the study hospital. As part of the RCT, the study team offered laboratory quality assurance, and supervision and training of paediatric ward staff using information on malaria epidemiology in the community. Data on clinical and blood slide confirmed cases of malaria from 2001 to 2005 were extracted from the hospital records.
  
  
  RESULTS
  The proportion of blood slides positive for malaria parasites had decreased from 21% in 2001 to 7% in 2005 (p < .01). The proportion of outpatient and inpatient cases diagnosed as malaria ranged between 34% and 28% from 2001 to 2004 and this decreased substantially to 17% after the introduction of the package of training and support in 2005 (p < .01). There was no clear trend in the ratio of blood slide examined versus total diagnosis of malaria.
  
  
  CONCLUSIONS
  It may be possible to change the diagnostic behaviour of clinicians by rigorous training using local malaria epidemiology data and supportive supervision.
authors.affiliation: Kilimanjaro Christian Medical College, PO 2240, Moshi, Tanzania. pmasika75@yahoo.com <pmasika75@yahoo.com>
authors.forename: Paul M
authors.initials: PM
authors.lastname: Masika
authors.forename: Waziri J
authors.initials: WJ
authors.lastname: Semarundu
authors.forename: Raymond
authors.initials: R
authors.lastname: Urassa
authors.forename: Jackline
authors.initials: J
authors.lastname: Mosha
authors.forename: Daniel
authors.initials: D
authors.lastname: Chandramohan
authors.forename: Roly D
authors.initials: RD
authors.lastname: Gosling
mesh_terms: D019411:Clinical Laboratory Techniques / Q000592:standards; D003951:Diagnostic Errors / Q000517:prevention & control*; D006801:Humans; D007223:Infant; D008288:Malaria / Q000097:blood / Q000469:parasitology* / Q000517:prevention & control*; D008859:Microscopy, Polarization / Q000379:methods / Q000592:standards*