A nutritional strategy to improve oxygenation and decrease morbidity in patients who have acute respiratory distress syndrome.
Enteral nutrition is increasingly becoming the standard of care for critically ill patients with the goal of providing nutritional support that prevents nutritional deficiencies and reduces morbidity. Furthermore, the development of nutritional strategies that dampen inflammation is an encouraging advance in the management of patients who have acute respiratory distress syndrome. This article discusses evidence from randomized, controlled studies that the use of a specialized nutritional formula containing eicosapentaenoic acid plus gamma-linolenic acid and elevated antioxidants offer physiologic and anti-inflammatory benefits over standard formulas.
DeMichele
Stephen J
SJ
Strategic and International R & D, Ross Products Division, Abbott Laboratories, 625 Cleveland Avenue, Columbus, OH 43215, USA. stephen.demichele@abbott.com
Wood
Steven M
SM
Wennberg
Ann K
AK
D000818:Animals; D002986:Clinical Trials as Topic; D015118:Eicosapentaenoic Acid; D004750:Enteral Nutrition; D005231:Fatty Acids, Unsaturated / Q000494:pharmacology; D006801:Humans; D009017:Morbidity; D010100:Oxygen / Q000378:metabolism; D012128:Respiratory Distress Syndrome / Q000453:epidemiology / Q000628:therapy*; D017965:gamma-Linolenic Acid / Q000494:pharmacology
D005231:Fatty Acids, Unsaturated; D017965:gamma-Linolenic Acid; D015118:Eicosapentaenoic Acid; D010100:Oxygen