title: Chemical genomics: dialed in transcriptional network control with non-steroidal glucocorticoid receptor modulators.
abstract: A recent study analyzed the transcriptional effects induced by a panel of non-steroidal glucocorticoid receptor modulators. The authors discover patterns of cell-, gene-, and mechanism-specific regulation, with implications for development of improved anti-inflammatory agents.
authors.affiliation: University of California-San Fransisco, 600 16th Street, GH-N512D, San Francisco, California 94143, USA.
authors.forename: Jasmina J
authors.initials: JJ
authors.lastname: Allen
authors.forename: Kevan M
authors.initials: KM
authors.lastname: Shokat
mesh_terms: D000818:Animals; D000893:Anti-Inflammatory Agents / Q000493:pharmacokinetics*; D023281:Genomics; D006706:Homeostasis; D008024:Ligands; D008954:Models, Biological; D018160:Receptors, Cytoplasmic and Nuclear / Q000235:genetics; D011965:Receptors, Glucocorticoid / Q000235:genetics*; D020845:Selective Estrogen Receptor Modulators / Q000493:pharmacokinetics; D013379:Substrate Specificity; D014158:Transcription, Genetic
chemical_list: D000893:Anti-Inflammatory Agents; D008024:Ligands; D018160:Receptors, Cytoplasmic and Nuclear; D011965:Receptors, Glucocorticoid; D020845:Selective Estrogen Receptor Modulators