title: Patterns of presentation and diagnosis of patients with Wegener's granulomatosis: ENT aspects.
abstract: METHODS
  a cross-sectional study.
  
  
  METHODS
  One hundred and ninety-nine patients with Wegener's granulomatosis belonging to a patient self-help group.
  
  
  METHODS
  Mode of initial presentation; diagnosis timescales and delay; rhinologic involvement; and treatment.
  
  
  RESULTS
  Sixty-three per cent of patients initially presented with ENT-related symptoms. Ninety-two per cent faced a delay in their diagnosis of more than one month, a pattern which has not improved over the last few decades and which compares unfavourably with North American figures. Rhinologic and otologic symptoms are a common occurrence in up to 85 and 50 per cent of Wegener's granulomatosis patients, respectively, attracting varying degrees of targeted treatment.
  
  
  CONCLUSIONS
  As sinonasal and other ENT symptoms are so common at the presentation of Wegener's granulomatosis, it is clear that the otolaryngologist has an important role in its diagnosis and treatment. There are long delays in the diagnosis and possible under-treatment of the ENT symptoms of this condition, highlighting the need for greater awareness, particularly in the ENT community.
authors.affiliation: ENT Department, University Hospital of Wales, Cardiff, Wales, UK. ibs@doctors.org.uk
authors.forename: I A
authors.initials: IA
authors.lastname: Srouji
authors.forename: P
authors.initials: P
authors.lastname: Andrews
authors.forename: C
authors.initials: C
authors.lastname: Edwards
authors.forename: V J
authors.initials: VJ
authors.lastname: Lund
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003430:Cross-Sectional Studies; D003937:Diagnosis, Differential; D005260:Female; D014890:Granulomatosis with Polyangiitis / Q000150:complications* / Q000175:diagnosis; D006801:Humans; D008297:Male; D008875:Middle Aged; D010038:Otorhinolaryngologic Diseases / Q000209:etiology*; D011795:Surveys and Questionnaires