title: Unusual beta-elimination of carbocyclic ketonucleosides catalyzed by silica gel.
abstract: Beta-elimination reactions occurred when carbocyclic ketonucleosides were treated with silica gel and alpha,beta-unsaturated ketonucleosides were obtained. The positions of ketone groups did not affect the occurrance of the elimination reaction. The yields of the reaction were influenced by the properties of leaving groups.
authors.affiliation: Beijing Institute of Pharmaceutical Chemistry, Beijing, China.
authors.forename: Xiaozhen
authors.initials: X
authors.lastname: Liu
authors.forename: Xin
authors.initials: X
authors.lastname: Guo
authors.forename: Fei
authors.initials: F
authors.lastname: Wang
authors.forename: Guangqing
authors.initials: G
authors.lastname: Lei
authors.forename: Dongdong
authors.initials: D
authors.lastname: Luo
mesh_terms: D000998:Antiviral Agents / Q000138:chemical synthesis*; D002384:Catalysis; D007659:Ketones / Q000138:chemical synthesis*; D009705:Nucleosides / Q000138:chemical synthesis*; D058428:Silica Gel; D012822:Silicon Dioxide / Q000737:chemistry*
chemical_list: D000998:Antiviral Agents; D007659:Ketones; D009705:Nucleosides; D058428:Silica Gel; D012822:Silicon Dioxide