Observation of DNA conformation changes by energy dissipation measurements on a quartz-crystal oscillator.
We developed the quartz-crystal oscillator coupled with an admittance analysis to obtain viscoelastic properties and hydration amounts of dsDNA in aqueous solutions. By using this technique, we found that dsDNA became elastic and dehydrated when dsDNA formed a compact structure by the addition of multivalent cations Co(NH(3))(6)(3+) in aqueous solutions.
Furusawa
Hiroyuki
H
Department of Biomolecular Engineering, Frontier Collaborative Research Center, Tokyo Institute of Technology and CREST, Japan Science and Technology Corporation (JST), 4259 Nagatsuta, Midori-ku, Yokohama 226-8501, Japan.
Ozeki
Tomomitsu
T
Okahata
Yoshio
Y
D003035:Cobalt / Q000737:chemistry; D004247:DNA / Q000737:chemistry*; D004563:Electrochemistry / Q000379:methods*; D009690:Nucleic Acid Conformation; D011791:Quartz / Q000737:chemistry*
C030862:cobalt ammonium complex; D011791:Quartz; D003035:Cobalt; D004247:DNA