title: GNOSIS: guidelines for neuro-oncology: standards for investigational studies--reporting of surgically based therapeutic clinical trials.
abstract: We present guidelines to standardize the reporting of surgically based neuro-oncology trials. The guidelines are summarized in a checklist format that can be used as a framework from which to construct a surgically based trial. This manuscript follows and is taken in part from GNOSIS: Guidelines for neuro-oncology: Standards for investigational studies-reporting of phase 1 and phase 2 clinical trials [Chang SM, Reynolds SL, Butowski N, Lamborn KR, Buckner JC, Kaplan RS, Bigner DD (2005) Neuro-oncology 7:425-434].
authors.affiliation: Neuro-oncology Service, Department of Neurological Surgery, University of California San Francisco, 400 Parnassus Avenue, A-808, San Francisco, CA 94143-0350, USA. changs@neurosurg.ucsf.edu
authors.forename: Susan
authors.initials: S
authors.lastname: Chang
authors.forename: Michael
authors.initials: M
authors.lastname: Vogelbaum
authors.forename: Frederick F
authors.initials: FF
authors.lastname: Lang
authors.forename: Stephen
authors.initials: S
authors.lastname: Haines
authors.forename: Sandeep
authors.initials: S
authors.lastname: Kunwar
authors.forename: E Antonio
authors.initials: EA
authors.lastname: Chiocca
authors.forename: Alessandro
authors.initials: A
authors.lastname: Olivi
authors.forename: Alfredo
authors.initials: A
authors.lastname: Quinones-Hinojosa
authors.forename: Andrew
authors.initials: A
authors.lastname: Parsa
authors.forename: Ronald
authors.initials: R
authors.lastname: Warnick
mesh_terms: D002986:Clinical Trials as Topic / Q000592:standards*; D003627:Data Interpretation, Statistical; D006801:Humans; D009423:Nervous System Neoplasms / Q000628:therapy*; D012107:Research Design / Q000592:standards*