title: [Hepatitis B virus: biology, immunopathogenesis, NK/NKT system in viral persistence].
abstract: In this review, the problem of hepatitis B is considered as related to the recent data on the biology of the viral agent, on the pathogenesis of disturbances that it causes in an organism as well as on accompanying deviations in its immune system. Special attention is paid to mechanisms of hepatitis B virus (HBV) persistence and the role of regulatory lymphocytes of NK/NKT system in this process. Some problems in further studies are specified.
authors.forename: R I
authors.initials: RI
authors.lastname: Sepiashvili
authors.forename: I P
authors.initials: IP
authors.lastname: Balmasova
authors.forename: E V
authors.initials: EV
authors.lastname: Kabanova
authors.forename: E S
authors.initials: ES
authors.lastname: Malova
authors.forename: T A
authors.initials: TA
authors.lastname: Slavianskaia
mesh_terms: D000818:Animals; D001679:Biogenic Amines / Q000378:metabolism; D003594:Cytoplasmic Granules / Q000737:chemistry; D006509:Hepatitis B / Q000276:immunology / Q000503:physiopathology / Q000821:virology; D006515:Hepatitis B virus / Q000502:physiology*; D006632:Histamine / Q000378:metabolism; D006801:Humans; D007694:Killer Cells, Natural / Q000166:cytology / Q000276:immunology*; D008213:Lymphocyte Activation; D014779:Virus Replication
chemical_list: D001679:Biogenic Amines; D006632:Histamine