Role of Thy-1,2+ cells in hemopoiesis regulation during hypoxia.
We studied the role of Thy-1,2+ cells in the regulation of hemopoiesis during oxygen deficiency of different genesis. These cells of the hemopoiesis-inducing microenvironment play an important role in the compensatory and adaptive reactions of the blood system to hypoxia. Thy-1,2+ cells directly or indirectly (via interaction with adherent myelokaryocytes) stimulated hemopoietic precursors. The effect of these cells on committed erythroid precursors was most pronounced.
Gol'dberg
E D
ED
Institute of Pharmacology, Tomsk Research Center, Siberian Division, Russian Academy of Medical Sciences.
Dygai
A M
AM
Zyuz'kov
G N
GN
D000818:Animals; D015687:Cell Hypoxia / Q000502:physiology; D002465:Cell Movement / Q000502:physiology; D006410:Hematopoiesis / Q000502:physiology*; D006412:Hematopoietic Stem Cells / Q000502:physiology*; D006706:Homeostasis / Q000502:physiology*; D051379:Mice; D013601:T-Lymphocytes / Q000378:metabolism / Q000502:physiology*; D018800:Thy-1 Antigens / Q000378:metabolism; D013997:Time Factors
D018800:Thy-1 Antigens