When is a heme transporter not a heme transporter? When it's a folate transporter.
Essential nutrients enter the body through a variety of specific transporter molecules expressed in the intestinal epithelium. A recent paper by elegantly demonstrates that one of these transporters, previously thought to carry heme, is in fact an important folate transporter.
Andrews
Nancy C
NC
Children's Hospital Boston and Harvard Medical School, Boston, MA 02115, USA. nandrews@enders.tch.harvard.edu
D000818:Animals; D001457:Anion Exchange Protein 1, Erythrocyte / Q000378:metabolism*; D001692:Biological Transport; D006367:HeLa Cells; D006418:Heme / Q000378:metabolism*; D006801:Humans; D026901:Membrane Transport Proteins / Q000378:metabolism*; D013763:Tetrahydrofolates / Q000378:metabolism*
D001457:Anion Exchange Protein 1, Erythrocyte; D026901:Membrane Transport Proteins; C454201:SLC4A1 protein, human; D013763:Tetrahydrofolates; D006418:Heme; C005984:5-methyltetrahydrofolate