title: Can alcohol-based hand-rub solutions cause you to lose your driver's license? Comparative cutaneous absorption of various alcohols.
abstract: We assessed cutaneous ethanol (ETOH) and isopropanol (ISOP) absorption after intensive (30 times per h) use of alcohol-based hand-rub solutions by healthcare workers (HCWs). ETOH was detectable in the breath of 6/20 HCWs (0.001 to 0.0025%) at 1 to 2 min postexposure and in the serum of 2/20 HCWs at 5 to 7 min postexposure. Serum ISOP levels were unrecordable at all time points.
authors.affiliation: Infectious Diseases Department, Austin Health, Studley Road, Heidelberg, Victoria 3084, Australia.
authors.forename: T L
authors.initials: TL
authors.lastname: Brown
authors.forename: S
authors.initials: S
authors.lastname: Gamon
authors.forename: P
authors.initials: P
authors.lastname: Tester
authors.forename: R
authors.initials: R
authors.lastname: Martin
authors.forename: K
authors.initials: K
authors.lastname: Hosking
authors.forename: G C
authors.initials: GC
authors.lastname: Bowkett
authors.forename: D
authors.initials: D
authors.lastname: Gerostamoulos
authors.forename: M L
authors.initials: ML
authors.lastname: Grayson
mesh_terms: D019840:2-Propanol / Q000493:pharmacokinetics; D000287:Administration, Topical; D000328:Adult; D000368:Aged; D000891:Anti-Infective Agents, Local / Q000008:administration & dosage / Q000097:blood* / Q000493:pharmacokinetics*; D002849:Chromatography, Gas; D000431:Ethanol / Q000008:administration & dosage / Q000097:blood* / Q000493:pharmacokinetics*; D005260:Female; D006282:Health Personnel; D006801:Humans; D008297:Male; D008875:Middle Aged; D012869:Skin Absorption
chemical_list: D000891:Anti-Infective Agents, Local; D000431:Ethanol; D019840:2-Propanol