A case of metoclopramide-induced oculogyric crisis in a 16-year-old girl with cystic fibrosis.
Oculogyric crisis is a neurologic reaction characterized by bilateral dystonic elevation of visual gaze as well as hyperextension of the neck. This reaction is most commonly explained as an adverse effect of numerous medications, such as dopamine receptor blocking agents or neuroleptic medications and traditional antipsychotic or antiemetic drugs, such as prochlorperazine or metoclopramide. A case of oculogyric crisis induced by metoclopramide is described in this paper.
Lou
Emil
E
Department of Medicine, Duke University Medical Center, Durham, NC, USA. emil.lou@duke.edu
Abou-Zeid
Nuhad
N
D000293:Adolescent; D000932:Antiemetics / Q000009:adverse effects*; D004155:Diphenhydramine / Q000627:therapeutic use; D018492:Dopamine Antagonists / Q000009:adverse effects*; D004421:Dystonia / Q000139:chemically induced; D005260:Female; D018662:Fundoplication / Q000009:adverse effects; D006634:Histamine H1 Antagonists / Q000627:therapeutic use; D006801:Humans; D008787:Metoclopramide / Q000009:adverse effects*; D009325:Nausea / Q000188:drug therapy / Q000209:etiology; D015835:Ocular Motility Disorders / Q000139:chemically induced* / Q000628:therapy; D014839:Vomiting / Q000188:drug therapy / Q000209:etiology
D000932:Antiemetics; D018492:Dopamine Antagonists; D006634:Histamine H1 Antagonists; D004155:Diphenhydramine; D008787:Metoclopramide