Effect of diode laser application with G-probe on ocular hypotony after trabeculectomy with mitomycin-C.
OBJECTIVE
The aim of this study was to assess the feasibility of a new technique to treat overfiltering blebs leading to hypotony after penetrating glaucoma surgery.


BACKGROUND
There is no previous report on diode laser application with G-probe on ocular hypotony consequent to trabeculectomy with adjunctive mitomycin-C.


METHODS
This clinical trial was conducted on eight eyes of eight patients with hypotony after trabeculectomy with adjunctive mitomycin-C. Ten to 12 diode laser (810 nm) spots were applied by G-probe over the bleb area with 2000-2500 mw power and for 1500-2000 msec duration; if the bleb was thin, the laser was applied on its border.


RESULTS
The mean age of patients was 29.1 +/- 12.4 years; two of them were female. Mean preoperative and postoperative intraocular pressure (IOPs) were 4.3 +/- 1.5 and 10.1 +/- 3.4 mm Hg, respectively (p = 0.017). Although the IOP increased in seven eyes (87.5%), the visual acuity increased > or =1 line in four (50%), remained stable in three (37.5%), and decreased 1 line in one (12.5%) after an average follow-up of 4 months. All of the blebs were notably smaller and pigmented. No complications occurred other than the need to start Timolol eye drops in one eye for controlling IOP and peaked pupil in two others.


CONCLUSIONS
Diode laser application with G-probe appears to be a useful modality of treatment for ocular hypotony and overfiltering blebs resulting from trabeculectomy with mitomycin-C.
Amini
Heydar
H
Department of Ophthalmology, Farabi Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Razeghinejad
Mohammad Reza
MR
Ghaffary
Elina
E
Abdollahi
Ali
A
D000293:Adolescent; D000328:Adult; D000477:Alkylating Agents / Q000009:adverse effects; D001768:Blister / Q000209:etiology / Q000532:radiotherapy*; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D053685:Laser Therapy; D008297:Male; D008875:Middle Aged; D016685:Mitomycin / Q000009:adverse effects; D015814:Ocular Hypotension / Q000209:etiology / Q000532:radiotherapy*; D014130:Trabeculectomy / Q000009:adverse effects*
D000477:Alkylating Agents; D016685:Mitomycin