[Erythrophagocytosis in rats long receiving sodium nitrite and alpha-tocopherol].
The effect of tocopherol in a dose of 150 mg/kg on the activity of erythrophagocytosis was studied in vitro during long-term nitrite intoxication. With sodium nitrite intake, activation of the cellular mechanisms of erythrodieresis was observed in all periods of an experiment, which caused blood cell changes. Administration of tocopherol in the presence of nitrite intoxication was found to reduce the phagocytic activity of macrophages, which prevented the development of anemia.
Ivanova
A S
AS
Pakhrova
O A
OA
Nazarov
S B
SB
D000818:Animals; D004195:Disease Models, Animal; D004781:Environmental Exposure / Q000009:adverse effects*; D018876:Environmental Illness / Q000097:blood* / Q000139:chemically induced; D004912:Erythrocytes / Q000187:drug effects*; D005260:Female; D005500:Follow-Up Studies; D010587:Phagocytosis / Q000187:drug effects*; D051381:Rats; D012977:Sodium Nitrite / Q000633:toxicity*; D013997:Time Factors; D024502:alpha-Tocopherol / Q000633:toxicity*
D024502:alpha-Tocopherol; D012977:Sodium Nitrite