Gene-environment interplay in attention-deficit hyperactivity disorder and the importance of a developmental perspective.
Attention-deficit hyperactivity disorder (ADHD) varies in its clinical presentation and course. Susceptibility gene variants for ADHD and associated antisocial behaviour are being identified with emerging evidence of gene-environment interaction. Genes and environmental factors that influence the origins of disorder are not necessarily the same as those that contribute to its course and outcome.
Thapar
Anita
A
Langley
Kate
K
Asherson
Philip
P
Gill
Michael
M
D000293:Adolescent; D000328:Adult; D001289:Attention Deficit Disorder with Hyperactivity / Q000453:epidemiology / Q000235:genetics*; D002648:Child; D002675:Child, Preschool; D002658:Developmental Disabilities; D020022:Genetic Predisposition to Disease / Q000235:genetics; D006801:Humans; D010375:Pedigree; D012307:Risk Factors; D012931:Social Environment