title: [Characteristics of blood aggregation in human subjects of different age categories during normobaric interval hypo-oxytraining].
abstract: Blood aggregation was studied in human subjects of different age groups given normobaric hypooxytraining. The experiment was performed with participation of two groups of volunteers: experienced human subjects well-adapted to hypoxia and young non-adapted subjects. NOT protocol included 7 min of breathing hypoxic mixture (90% N2 and 10% O2) and 3 min of breathing atmospheric air at room temperature, 6 cycles every other day during one month. Blood aggregation was assessed by 26 parameters with the use of a multifunctional diagnostic system that permitted biophysical (rheologic), biochemical (coagulative) and mathematic (systemic) diagnostics. Two groups of the human subjects displayed significantly different reactions to of blood aggregation to the extreme factor (NOT). There was a marked dependence of the blood aggregation reaction to the hypoxic factor on the body protective-adaptive potential. Our data substantiate the need to develop NOT protocols for pilots of specific ages.
authors.forename: L A
authors.initials: LA
authors.lastname: Subbotina
authors.forename: V K
authors.initials: VK
authors.lastname: Stepanov
authors.forename: M V
authors.initials: MV
authors.lastname: Dvornikov
mesh_terms: D000222:Adaptation, Physiological / Q000502:physiology*; D000328:Adult; D000337:Aerospace Medicine; D000367:Age Factors; D004903:Erythrocyte Aggregation / Q000502:physiology*; D006801:Humans; D000860:Hypoxia / Q000097:blood*; D008875:Middle Aged; D012016:Reference Values