Insular cortex hypoperfusion and acute phase blood glucose after stroke: a CT perfusion study.
OBJECTIVE
Insular cortex ischemia is proposed to mediate a sympathetic stimulus that leads to acute hyperglycemia after stroke.


METHODS
We retrospectively analyzed insular perfusion on perfusion CT (median 180 minutes after onset) in 35 patients.


RESULTS
We found no association of hypoperfusion (relative cerebral blood flow <0.51) with early (<6 hours) or delayed (<72 hours) hyperglycemia, or hemispheric lateralization.


CONCLUSIONS
Insular cortex hypoperfusion <6 hours after stroke onset was not associated with hyperglycemia.
Moreton
Fiona C
FC
Division of Clinical Neurosciences, University of Glasgow, Institute of Neurological Sciences, Southern General Hospital, Glasgow G51 4TF, Scotland, UK.
McCormick
Michael
M
Muir
Keith W
KW
D000368:Aged; D000369:Aged, 80 and over; D001786:Blood Glucose / Q000502:physiology*; D002540:Cerebral Cortex / Q000098:blood supply* / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D006943:Hyperglycemia / Q000000981:diagnostic imaging / Q000209:etiology; D008297:Male; D008875:Middle Aged; D010477:Perfusion / Q000379:methods; D012189:Retrospective Studies; D020521:Stroke / Q000150:complications / Q000000981:diagnostic imaging* / Q000503:physiopathology; D013997:Time Factors; D014057:Tomography, X-Ray Computed / Q000379:methods*
D001786:Blood Glucose