[Clinical observation on Qidi Yiqi Yangyin Huoxue Recipe in treating diabetic nephropathy at stage III and IV].
OBJECTIVE
To observe the clinical effect of Qidi Yiqi Yangyin Huoxue Recipe (QYYHR) on diabetic nephropathy (DN) at stage III and IV.


METHODS
One hundred type 2 DN patients of qi-yin deficiency with blood-stasis syndrome were randomly divided into two groups, all were treated with basal hypoglycemic treatment but with QYYHR given to the treatment group additionally for 3 months. The symptoms were observed, blood glucose, urinary albumin excretion rate (UAER), blood urea nitrogen (BUN), creatinine (Cr) and hemorheological parameters were detected before and after treatment.


RESULTS
The total effective rate was higher in the treatment group than that in the control group (89.6% vs. 68.1%, P < 0.01), and the improvement of UAER, BUN, Cr and hemorheological parameters was also significantly better in the former than in the latter (P < 0.05).


CONCLUSIONS
QYYHR has favorable effects on type 2 DN of qi-yin deficiency with blood-stasis syndrome.
Zou
Li-hong
LH
The People' s Hospital of Jilin Province, Changchun.
Zhang
Jian-hua
JH
Liu
Ping-fu
PF
D000328:Adult; D000368:Aged; D000419:Albuminuria / Q000652:urine; D001786:Blood Glucose / Q000378:metabolism; D001806:Blood Urea Nitrogen; D003404:Creatinine / Q000097:blood; D003924:Diabetes Mellitus, Type 2 / Q000150:complications; D003928:Diabetic Nephropathies / Q000097:blood / Q000188:drug therapy* / Q000209:etiology; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D018056:Hemorheology / Q000187:drug effects; D006801:Humans; D008297:Male; D008875:Middle Aged; D008517:Phytotherapy; D019413:Qi; D016896:Treatment Outcome; D016710:Yin Deficiency / Q000188:drug therapy*
D001786:Blood Glucose; D004365:Drugs, Chinese Herbal; C527660:qidi yiqi yangyin huoxue; D003404:Creatinine