title: Evolving sensitivity.
abstract: Engineering gene circuits with novel functions holds promise for broad applications in biology, engineering, and medicine. Directed evolution complements rational design as an important strategy for optimizing gene circuits and circuit elements.
authors.affiliation: Department of Biomedical Engineering and Institute for Genome Sciences and Policy, Duke University, Durham, North Carolina 27708, USA.
authors.forename: Hao
authors.initials: H
authors.lastname: Song
authors.forename: Lingchong
authors.initials: L
authors.lastname: You
mesh_terms: D019020:Directed Molecular Evolution / Q000379:methods*; D005818:Genetic Engineering / Q000379:methods*; D008957:Models, Genetic