title: [Two cases of acute renal failure associated with non-fulminant acute hepatitis A].
abstract: Hepatitis A is generally regarded as a mild, self-limiting disease of the liver. Acute renal failure has rarely been reported in association with non-fulminant acute hepatitis A. Acute tubular necrosis is the most common form of renal injury in such patients. We recently experienced two cases of hepatitis A in which acute renal failure occurred early in the course of the illness and had a clinical course suggestive of acute tubular necrosis. In both patients, the clinical course of renal dysfunction was almost parallel to that of hepatic dysfunction. Hemodialysis was performed in patient 1 because of severe uremia despite maintaining urine output more than 2,000 mL per day. On the other hand, hemodialysis was not performed in patient 2 who showed a rapid recovery of renal dysfunction. The renal biopsy of patient 1 demonstrated typical findings of acute tubular necrosis on microscopy.
authors.affiliation: Department of Internal Medicine, Kangdong Sacred Heart Hospital, Hallym University College of Medicine, Gangdong-Gu, Seoul, Korea.
authors.forename: Sung Eun
authors.initials: SE
authors.lastname: Kim
authors.forename: Soo Jin
authors.initials: SJ
authors.lastname: Kim
authors.forename: Hyoung Su
authors.initials: HS
authors.lastname: Kim
authors.forename: Hee Sun
authors.initials: HS
authors.lastname: Kim
authors.forename: Eun Sook
authors.initials: ES
authors.lastname: Nam
authors.forename: Sang Kyu
authors.initials: SK
authors.lastname: Lee
authors.forename: Su Rin
authors.initials: SR
authors.lastname: Shin
authors.forename: Hak Yang
authors.initials: HY
authors.lastname: Kim
mesh_terms: D000208:Acute Disease; D058186:Acute Kidney Injury / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D000328:Adult; D006506:Hepatitis A / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D008297:Male; D006435:Renal Dialysis / Q000379:methods