title: Genetic diversity and population structure of Mycobacterium tuberculosis in HIV-1-infected compared with uninfected individuals in Burkina Faso.
abstract: HIV-1 infection and HIV-1-induced immune deficiency may play a role in selecting particular Mycobacterium tuberculosis (MTB) strains (i.e. genotypes). We compared 43 MTB isolates obtained from HIV-1-infected patients with 77 MTB isolates obtained from HIV-1-uninfected patients in Burkina Faso, by means of DNA fingerprinting methods (MIRU-VNTR plus spoligotyping). This study suggests a lack of structure of the MTB population caused by HIV-1 infection and a similar genetic diversity of MTB in HIV-1-infected compared with uninfected individuals.
authors.affiliation: Laboratoire de Bactériologie, Hôpital Universitaire Arnaud de Villeneuve, Montpellier, France.
authors.forename: Sylvain
authors.initials: S
authors.lastname: Godreuil
authors.forename: François
authors.initials: F
authors.lastname: Renaud
authors.forename: Philippe
authors.initials: P
authors.lastname: Van de Perre
authors.forename: Christian
authors.initials: C
authors.lastname: Carriere
authors.forename: Gabriela
authors.initials: G
authors.lastname: Torrea
authors.forename: Anne-Laure
authors.initials: AL
authors.lastname: Banũls
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000382:microbiology*; D000293:Adolescent; D000328:Adult; D000368:Aged; D002050:Burkina Faso; D016172:DNA Fingerprinting; D004269:DNA, Bacterial / Q000235:genetics; D003906:Developing Countries; D005260:Female; D014644:Genetic Variation; D015497:HIV-1; D006801:Humans; D008297:Male; D008875:Middle Aged; D009169:Mycobacterium tuberculosis / Q000235:genetics* / Q000302:isolation & purification; D014397:Tuberculosis, Pulmonary / Q000382:microbiology*
chemical_list: D004269:DNA, Bacterial