title: Radical-scavenging activities of new hydroxylated ursane triterpenes from cv. Annurca apples.
abstract: Two new ursolic acid triterpene derivatives, compounds 2 and 3, have been isolated from cv. Annurca apple fruit, a high-quality apple variety widely cultivated in southern Italy, together with the known 2-oxopomolic acid (1). The new compounds were identified by means of different spectroscopic techniques as 3-epi-2-oxopomolic acid (= (3alpha)-3,19-dihydroxy-2-oxours-12-en-28-oic acid; 2) and (1alpha)-1-hydroxy-3-oxours-12-en-28-oic acid (3). Compounds 1-3 were tested for their radical-scavenging activities with the aid of a 1,1-diphenyl-2-picrylhydrazyl (DPPH) assay (Fig. 2). All three constituents showed activities similar to that of the reference antioxidant alpha-tocopherol (vitamin E).
authors.affiliation: Dipartimento di Scienze della Vita, Seconda Università degli Studi di Napoli, via Vivaldi 43, I-81100 Caserta.
authors.forename: Brigida
authors.initials: B
authors.lastname: D'Abrosca
authors.forename: Antonio
authors.initials: A
authors.lastname: Fiorentino
authors.forename: Pietro
authors.initials: P
authors.lastname: Monaco
authors.forename: Severina
authors.initials: S
authors.lastname: Pacifico
mesh_terms: D016166:Free Radical Scavengers / Q000737:chemistry*; D005638:Fruit / Q000737:chemistry*; D027845:Malus / Q000737:chemistry*; D015394:Molecular Structure; D013237:Stereoisomerism; D014315:Triterpenes / Q000737:chemistry*
chemical_list: C516968:1-hydroxy-3-oxours-12-en-28-oic acid; C412808:2-oxopomolic acid; D016166:Free Radical Scavengers; D014315:Triterpenes