title: Photoreceptor status after resolved macular edema in branch retinal vein occlusion treated with tissue plasminogen activator.
abstract: OBJECTIVE
  To evaluate the integrity of photoreceptors in macular edema (ME) associated with branch retinal vein occlusion after intravitreal tissue plasminogen activator.
  
  
  METHODS
  Retrospective, interventional case series.
  
  
  METHODS
  Nineteen eyes with ME by branch retinal vein occlusion were treated with intravitreal tissue plasminogen activator injection. We assessed visual acuity (VA) and the presence or absence in the fovea of a third high reflectance band (HRB) by optical coherence tomography at the final visit.
  
  
  RESULTS
  No differences were found in age, preoperative VA, and foveal thickness between the groups with or without the third HRB. After treatment, the mean VA improved significantly (P < .05) in both groups. At the final visit, the mean VA in the group without HRB was significantly poorer than the group with HRB (P = .0042); foveal thickness did not differ between the groups.
  
  
  CONCLUSIONS
  The integrity of the third HRB in the fovea is associated with VA after the resolution of ME.
authors.affiliation: Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Sakyo-ku, Kyoto 606-8507, Japan.
authors.forename: Tomoaki
authors.initials: T
authors.lastname: Murakami
authors.forename: Akitaka
authors.initials: A
authors.lastname: Tsujikawa
authors.forename: Masafumi
authors.initials: M
authors.lastname: Ohta
authors.forename: Kazuaki
authors.initials: K
authors.lastname: Miyamoto
authors.forename: Mihori
authors.initials: M
authors.lastname: Kita
authors.forename: Daiseke
authors.initials: D
authors.lastname: Watanabe
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Takagi
authors.forename: Nagahisa
authors.initials: N
authors.lastname: Yoshimura
mesh_terms: D005260:Female; D005343:Fibrinolytic Agents / Q000627:therapeutic use*; D005584:Fovea Centralis; D006801:Humans; D007267:Injections; D008269:Macular Edema / Q000188:drug therapy* / Q000209:etiology; D008297:Male; D008875:Middle Aged; D020419:Photoreceptor Cells, Vertebrate / Q000473:pathology*; D012170:Retinal Vein Occlusion / Q000150:complications*; D012189:Retrospective Studies; D010959:Tissue Plasminogen Activator / Q000627:therapeutic use*; D041623:Tomography, Optical Coherence; D014690:Venous Pressure; D014792:Visual Acuity / Q000502:physiology; D014822:Vitreous Body
chemical_list: D005343:Fibrinolytic Agents; D010959:Tissue Plasminogen Activator