Effects of lesions of the bed nucleus of the stria terminalis, lateral hypothalamus, or insular cortex on conditioned taste aversion and conditioned odor aversion.
The effects of permanent forebrain lesions on conditioned taste aversions (CTAs) and conditioned odor aversions (COAs) were examined in 3 experiments. In Experiment 1, lesions of the bed nucleus of the stria terminalis had no influence on CTA or COA acquisition. Although lesions of the lateral hypothalamus induced severe hypodipsia in Experiment 2, they did not prevent the acquisition of CTAs or COAs. Finally, in Experiment 3, lesions of the insular cortex retarded CTA acquisition but had no influence on COA acquisition. The implications of these findings are discussed with regard to the forebrain influence on parabrachial nucleus function during CTA acquisition.
Roman
Christopher
C
Department of Psychology, University of Illinois at Chicago, Chicago, IL 60607, USA.
Nebieridze
Nino
N
Sastre
Aristides
A
Reilly
Steve
S
D000704:Analysis of Variance; D000818:Animals; D001362:Avoidance Learning / Q000502:physiology*; D001522:Behavior, Animal / Q000502:physiology; D002540:Cerebral Cortex / Q000293:injuries* / Q000503:physiopathology; D003214:Conditioning, Classical; D007026:Hypothalamic Area, Lateral / Q000293:injuries* / Q000503:physiopathology; D008297:Male; D009812:Odorants; D051381:Rats; D017207:Rats, Sprague-Dawley; D012686:Septal Nuclei / Q000293:injuries* / Q000503:physiopathology; D013649:Taste