Suicide rates in the Lundby cohort before and after the introduction of tricyclic antidepressant drugs.
The Lundby cohort consisting of 3563 subjects was investigated in 1947, 1957, 1972, and 1997. It represents a rural, but gradually urbanized Swedish sample without non-Nordic immigrants and offers an opportunity to study suicide rates before and after the introduction of tricyclic antidepressant drugs in Sweden in 1962. Since then, a fall in suicide rate among depressed individuals was observed, while there was an increase in the overall suicide rate. In fact, in 1977-1992 other psychiatric diagnoses, alcohol disorder included, were more often associated with suicide than depression. No psychiatric or alcohol disorder was registered in 7% of the suicides.
Nettelbladt
Per
P
Department of Clinical Sciences, Division of Psychiatry, The Lundby Study, Lund University, SE-221 85, Lund, Sweden.
Mattisson
Cecilia
C
Bogren
Mats
M
Holmqvist
Marika
M
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000437:Alcoholism / Q000401:mortality; D000929:Antidepressive Agents, Tricyclic / Q000627:therapeutic use*; D015331:Cohort Studies; D003430:Cross-Sectional Studies; D003866:Depressive Disorder / Q000188:drug therapy* / Q000401:mortality*; D005260:Female; D006801:Humans; D015994:Incidence; D008137:Longitudinal Studies; D008297:Male; D001523:Mental Disorders / Q000401:mortality; D008875:Middle Aged; D013405:Suicide / Q000706:statistics & numerical data* / Q000639:trends; D013548:Sweden; D000092864:Suicide Prevention
D000929:Antidepressive Agents, Tricyclic