title: Severe scoliosis associated with Costello syndrome: a case report.
abstract: Costello syndrome is characterised by dwarfism, unique cutaneous lesions, a distinct facial gestalt, and mental retardation. There have been no detailed reports of severe spinal deformities requiring surgical treatment as a complication of Costello syndrome. We report a case of a 10-year-old girl with progressive scoliosis associated with Costello syndrome. She underwent anterior release and posterior surgical correction and fusion from T5 to L2 using a third generation hook and rod system plus spinous process wiring. Congenital portal vein deficiency and coagulopathy were other major complications. At 15-month follow-up, the patient had good balance and no evidence of instrumentation failure.
authors.affiliation: Department of Orthopaedic Surgery, National Defense Medical College, Namiki, Tokorozawa, Saitama, Japan. tmotosuneya@yahoo.co.jp
authors.forename: T
authors.initials: T
authors.lastname: Motosuneya
authors.forename: T
authors.initials: T
authors.lastname: Asazuma
authors.forename: T
authors.initials: T
authors.lastname: Tsuji
authors.forename: H
authors.initials: H
authors.lastname: Watanabe
authors.forename: Y
authors.initials: Y
authors.lastname: Nakayama
authors.forename: K
authors.initials: K
authors.lastname: Nemoto
mesh_terms: D000015:Abnormalities, Multiple; D002648:Child; D004392:Dwarfism / Q000150:complications*; D005145:Face / Q000002:abnormalities*; D005260:Female; D006801:Humans; D008607:Intellectual Disability / Q000150:complications*; D012600:Scoliosis / Q000150:complications* / Q000601:surgery*; D012720:Severity of Illness Index; D012868:Skin Abnormalities / Q000150:complications*; D013577:Syndrome