title: The relationship between previous fluoroquinolone use and levofloxacin resistance in Helicobacter pylori infection.
abstract: The relationship between prior fluoroquinolone use and levofloxacin resistance in Helicobacter pylori infection is unknown. Among 125 enrolled patients, 8.8% had H. pylori isolates that were resistant to levofloxacin. Levofloxacin resistance was associated with any prior fluoroquinolone use over the previous 10 years and with the total number of fluoroquinolone courses prescribed (P<.001).
authors.affiliation: Native Medical Center, Anchorage, Alaska, USA.
authors.forename: John J
authors.initials: JJ
authors.lastname: Carothers
authors.forename: Michael G
authors.initials: MG
authors.lastname: Bruce
authors.forename: Thomas W
authors.initials: TW
authors.lastname: Hennessy
authors.forename: Michael
authors.initials: M
authors.lastname: Bensler
authors.forename: Julie M
authors.initials: JM
authors.lastname: Morris
authors.forename: Alisa L
authors.initials: AL
authors.lastname: Reasonover
authors.forename: Debby A
authors.initials: DA
authors.lastname: Hurlburt
authors.forename: Alan J
authors.initials: AJ
authors.lastname: Parkinson
authors.forename: John M
authors.initials: JM
authors.lastname: Coleman
authors.forename: Brian J
authors.initials: BJ
authors.lastname: McMahon
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D024901:Drug Resistance, Multiple, Bacterial; D005260:Female; D016481:Helicobacter Infections / Q000188:drug therapy* / Q000382:microbiology*; D016480:Helicobacter pylori / Q000187:drug effects*; D006801:Humans; D064704:Levofloxacin; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D015242:Ofloxacin / Q000494:pharmacology*
chemical_list: D000900:Anti-Bacterial Agents; D064704:Levofloxacin; D015242:Ofloxacin