title: Endoluminal fundoplication.
abstract: In GERD patients in whom pharmacological therapies are ineffective and anti-reflux surgery is not indicated, a viable option could be proposed. To date, several endoscopic antireflux procedures, involving sewing, injection and/or implant, and radiofrequency are available. The sewing techniques demonstrated good clinical results, with reduction in proton pump inhibitors consumption; despite significant changes in esophageal manometry and/or acid exposure time reduction and healing of esophagitis were noted only in few patients.
authors.affiliation: Digestive Endoscopy Unit, Catholic University of Rome, Largo Francesco Vito 1, 00168 Rome, Italy.
authors.forename: Michele
authors.initials: M
authors.lastname: Marchese
authors.forename: Cristiano
authors.initials: C
authors.lastname: Spada
authors.forename: Guido
authors.initials: G
authors.lastname: Costamagna
mesh_terms: D016099:Endoscopy, Gastrointestinal / Q000379:methods*; D018662:Fundoplication / Q000295:instrumentation / Q000379:methods*; D005764:Gastroesophageal Reflux / Q000601:surgery*; D006801:Humans