title: Reduced elimination of Methotrexate in an adult with trisomy 21 and acute lymphoblastic leukaemia.
authors.forename: Jecko
authors.initials: J
authors.lastname: Thachil
mesh_terms: D000328:Adult; D000964:Antimetabolites, Antineoplastic / Q000097:blood* / Q000627:therapeutic use; D004314:Down Syndrome / Q000378:metabolism*; D005260:Female; D006801:Humans; D008727:Methotrexate / Q000097:blood* / Q000627:therapeutic use; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000188:drug therapy*
chemical_list: D000964:Antimetabolites, Antineoplastic; D008727:Methotrexate