Comparative analysis of direction, value, and duration atrial pressure of shifts caused by depressor agents.
Shifts in right- and left-atrial pressure after administration of acetylcholine, histamine, or isoproterenol to cats were oppositely directed in 69% cases; both parameters decreased in 11% cases (changes were more pronounced in the right atrium) and increased in 20% cases (similar shifts). Changes in the left-atrial pressure persisted for a longer time (compared to those in the right atrium) and their dynamics was similar to that of venous return and cardiac output.
Tkachenko
B I
BI
Department of Visceral System Physiology, Institute of Experimental Medicine, Russian Academy of Medical Sciences, St. Petersburg.
Evlakhov
V I
VI
Poyasov
I Z
IZ
D000109:Acetylcholine / Q000494:pharmacology; D000818:Animals; D016275:Atrial Function / Q000187:drug effects / Q000502:physiology*; D001775:Blood Circulation / Q000187:drug effects*; D001794:Blood Pressure / Q000187:drug effects*; D002302:Cardiac Output / Q000187:drug effects*; D002317:Cardiovascular Agents / Q000494:pharmacology*; D002415:Cats; D006632:Histamine / Q000494:pharmacology; D007545:Isoproterenol / Q000494:pharmacology; D013997:Time Factors
D002317:Cardiovascular Agents; D006632:Histamine; D007545:Isoproterenol; D000109:Acetylcholine