title: Glycosylation in room temperature ionic liquid using unprotected and unactivated donors.
abstract: Glycosylation in room temperature ionic liquid is demonstrated using unprotected and unactivated donors. Modest yields of simple benzyl glycosides and disaccharides of glucose, mannose and N-acetylgalactosamine were obtained in 1-ethyl-3-methylimidazolium benzoate with Amberlite IR-120 (H(+)) resin or p-toluenesulfonic acid as promoters.
authors.affiliation: Department of Chemical and Biological Engineering, Biotechnology 4005, Rensselaer Polytechnic Institute, 110, 8th Street, Troy, NY 12180, USA.
authors.forename: Tae-Joon
authors.initials: TJ
authors.lastname: Park
authors.forename: Michel
authors.initials: M
authors.lastname: Weïwer
authors.forename: Xuejun
authors.initials: X
authors.lastname: Yuan
authors.forename: Sultan N
authors.initials: SN
authors.lastname: Baytas
authors.forename: Eva M
authors.initials: EM
authors.lastname: Munoz
authors.forename: Saravanababu
authors.initials: S
authors.lastname: Murugesan
authors.forename: Robert J
authors.initials: RJ
authors.lastname: Linhardt
mesh_terms: D000116:Acetylgalactosamine / Q000737:chemistry; D001557:Benzenesulfonates; D002240:Carbohydrate Sequence; D002411:Cation Exchange Resins; D004187:Disaccharides / Q000138:chemical synthesis*; D005947:Glucose / Q000737:chemistry; D006027:Glycosides / Q000138:chemical synthesis*; D006031:Glycosylation; D007093:Imidazoles / Q000737:chemistry*; D008358:Mannose / Q000737:chemistry; D008969:Molecular Sequence Data; D011137:Polystyrenes; D021241:Spectrometry, Mass, Electrospray Ionization; D013696:Temperature
chemical_list: D001557:Benzenesulfonates; D002411:Cation Exchange Resins; D004187:Disaccharides; D006027:Glycosides; D007093:Imidazoles; D011137:Polystyrenes; C025242:Amberlite IR-120; D005947:Glucose; D000116:Acetylgalactosamine; D008358:Mannose; C029501:4-toluenesulfonic acid; C518739:1-ethyl-3-methylimidazolium