[Use of different types of target propofol concentration-control infusion: theoretical and practical aspects].
Examinations were made in 105 patients who had undergone total intravenous anesthesia on the basis of the immune circulating components (ICC) of propofol by different pharmacokinetic models--Marsh and Schnider, by aiming at plasma or an effector zone. Along with good controllability of ICC-anesthesia, with theoretical and practical differences of the employed models are shown. The capacities of an up-to-date universal perfusor are demonstrated, by using Asena PK as an example. Practical recommendations on its application are given. The prospects of anesthesia automation are briefly discussed.
Stamov
V I
VI
Mizikov
V M
VM
Deshko
Iu V
IuV
D000328:Adult; D000368:Aged; D000771:Anesthesia, Intravenous / Q000379:methods*; D018686:Anesthetics, Intravenous / Q000008:administration & dosage / Q000493:pharmacokinetics*; D001331:Automation; D005260:Female; D006801:Humans; D007262:Infusions, Intravenous; D008297:Male; D008875:Middle Aged; D008991:Monitoring, Physiologic; D015742:Propofol / Q000008:administration & dosage / Q000493:pharmacokinetics*
D018686:Anesthetics, Intravenous; D015742:Propofol