title: Mechanical properties and biological behavior of carbon nanotube/polycarbosilane composites for implant materials.
abstract: Multiwalled carbon nanotube/polycarbosilane (MWCNT/PCS) composites were fabricated by the spark plasma sintering (SPS) method. The MWCNT/PCS composites consisted of MWCNTs and nanosized SiC particles pyrolyzed from PCS and possessing good mechanical properties for bone tissue repair or dental implantation. The MWCNT/PCS composites were implanted in the subcutaneous tissue and femur of rats at 1 and 4 weeks after implantation. Histological investigations showed that there was little inflammatory response in the subcutaneous tissue, and newly formed bone tissue was observed in the femur. These results indicated that the MWCNT/PCS composite had little prophlogistic effect and good osteoconductivity. The study suggested the possibility that the MWCNT/PCS composite could be a candidate bone-substitute and dental-implant material in the future.
authors.affiliation: Graduate School of Dental Medicine, Hokkaido University, Sapporo 060-8586, Japan. ww1120@den.hokudai.ac.jp
authors.forename: Wei
authors.initials: W
authors.lastname: Wang
authors.forename: Fumio
authors.initials: F
authors.lastname: Watari
authors.forename: Mamoru
authors.initials: M
authors.lastname: Omori
authors.forename: Susan
authors.initials: S
authors.lastname: Liao
authors.forename: Yuhe
authors.initials: Y
authors.lastname: Zhu
authors.forename: Atsuro
authors.initials: A
authors.lastname: Yokoyama
authors.forename: Motohiro
authors.initials: M
authors.lastname: Uo
authors.forename: Hisamichi
authors.initials: H
authors.lastname: Kimura
authors.forename: Akira
authors.initials: A
authors.lastname: Ohkubo
mesh_terms: D000818:Animals; D001672:Biocompatible Materials / Q000737:chemistry* / Q000494:pharmacology; D018786:Bone Substitutes / Q000737:chemistry* / Q000494:pharmacology; D015921:Dental Implants; D008422:Materials Testing; D019563:Mechanics; D008855:Microscopy, Electron, Scanning; D046529:Microscopy, Electron, Transmission; D053761:Nanocomposites / Q000737:chemistry*; D037742:Nanotubes, Carbon / Q000737:chemistry*; D051381:Rats; D011919:Rats, Inbred Strains; D012821:Silanes / Q000737:chemistry
chemical_list: D001672:Biocompatible Materials; D018786:Bone Substitutes; D015921:Dental Implants; D037742:Nanotubes, Carbon; D012821:Silanes; C504072:carbosilane