[Biological function of CoQ10 and its effect on the quality of spermatozoa].
Oxidative damage is one of the important factors inducing the regression of sperm quality. CoQ10 is a liposoluble antioxidant that exists in mitochondria and its levels in semen and spermatozoa have an important role in the oxidation resistance of the male genital system. Exogenous administration of CoQ10 can improve the sperm quality and reproductive ability of infertile patients as well as exert the effects of an adjunctive therapy on male infertility. This review describes the biological function of CoQ10 and its effect on the quality of spermatozoa and its effect as an adjunctive therapy on male infertility.
Li
Wei
W
Institute of Clinical Laboratory Medicine, Nanjing General Hospital of Nanjing Command, PLA, Nanjing, Jiangsu 210002, China.
Li
Ke
K
Huang
Yu-feng
YF
D003067:Coenzymes / Q000502:physiology / Q000627:therapeutic use; D006801:Humans; D007248:Infertility, Male / Q000628:therapy; D008297:Male; D012661:Semen; D013076:Sperm Count; D013081:Sperm Motility; D014451:Ubiquinone / Q000031:analogs & derivatives* / Q000502:physiology / Q000627:therapeutic use
D003067:Coenzymes; D014451:Ubiquinone; C024989:coenzyme Q10