Clerodane diterpenoids from Salvia splendens.
Four new clerodane diterpenoids, salvisplendins A-D (1-4), have been isolated from an acetone extract of the flowers of Salvia splendens, together with an artifact (5), arising from salvisplendin D (4) by addition of diazomethane, and the already known clerodane olearin (6). The structures of the new compounds (1-5) were established mainly by 1D and 2D NMR spectroscopic studies and, in the case of salvisplendin A (1), by chemical correlation with splenolide B (7). Complete 1H and 13C NMR assignments for olearin (6), not published hitherto, are also reported.
Fontana
Gianfranco
G
Dipartimento di Chimica Organica E. Paterno, Università degli Studi di Palermo, Parco d'Orleans 2, I-90128 Palermo, Italy.
Savona
Giuseppe
G
Rodríguez
Benjamín
B
D045785:Diterpenes, Clerodane / Q000737:chemistry / Q000302:isolation & purification*; D035264:Flowers / Q000737:chemistry; D007558:Italy; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D010946:Plants, Medicinal / Q000737:chemistry*; D027544:Salvia / Q000737:chemistry*
D045785:Diterpenes, Clerodane