Evaluation of hyperbaric oxygen treatment of neuropsychiatric disorders following traumatic brain injury.
BACKGROUND
Improvement of clinical symptoms following hyperbaric oxygen (HBO) treatment of neuropsychiatric disorders arising from traumatic brain injury was proved by our previous study. This study was aim to obtain the evidence of other changes.


METHODS
Three hundred and ten patients with neuropsychiatric disorders arising from traumatic brain injury were treated twice with hyperbaric oxygen. Cerebral single photon emissions computed tomography (SPECT) images and computed tomography scans (CT) before and after hyperbaric oxygen treatment, were compared.


RESULTS
Before treatment, the proportion of abnormal cerebral changes detected by SPECT was 81.3% but only 15.2% by CT. After HBO treatment, 70.3% of SPECT scans showed no abnormalities and these patients were clinically improved. Treatment improved regional cerebral blood flow.


CONCLUSIONS
SPECT was much more sensitive than CT in the diagnosis of neuropsychiatric disorders following hyperbaric oxygen treatment of neuropsychiatric disorders arising from traumatic brain injury.
Shi
Xiao-yan
XY
Neuroscience Care Unit, Second Affiliated Hospital of Zhejiang University College of Medicine, Hangzhou, China. xys0571@hotmail.com
Tang
Zhong-quan
ZQ
Sun
Da
D
He
Xiao-jun
XJ
D000293:Adolescent; D000328:Adult; D000368:Aged; D001930:Brain Injuries / Q000150:complications*; D002648:Child; D005260:Female; D006801:Humans; D006931:Hyperbaric Oxygenation; D008297:Male; D001523:Mental Disorders / Q000175:diagnosis / Q000628:therapy*; D008875:Middle Aged; D009422:Nervous System Diseases / Q000175:diagnosis / Q000628:therapy*