Infectious keratitis caused by Stenotrophomonas maltophilia and yeast simultaneously.
OBJECTIVE
To report a case of coinfection of the human cornea by Stenotrophomonas maltophilia and yeast.


METHODS
A 59-year-old woman presented with a corneal ulcer. The corneal lesion worsened suddenly after initial improvement with empirical antibiotic treatment. A culture revealed S. maltophilia. The keratitis rapidly progressed despite treatment with sensitivity-proven antibiotic agents. Eventually, the patient underwent therapeutic penetrating keratoplasty.


RESULTS
Pathology of the cornea showed yeast forms and pseudohyphae scattered over the cornea. After surgery, the inflammation was controlled without any signs of recurrent infection.


CONCLUSIONS
Coinfection of the cornea by S. maltophilia and yeast may occur in a susceptible cornea and may not be controlled by standard medical treatment.
Kim
Jun-Heon
JH
Department of Ophthalmology, Korea University College of Medicine, Seoul, Korea.
Shin
Hyoung Ho
HH
Song
Jong-Suk
JS
Kim
Hyo-Myung
HM
D003320:Corneal Ulcer / Q000175:diagnosis / Q000382:microbiology* / Q000601:surgery; D015818:Eye Infections, Bacterial / Q000175:diagnosis / Q000382:microbiology* / Q000601:surgery; D015821:Eye Infections, Fungal / Q000175:diagnosis / Q000382:microbiology* / Q000601:surgery; D005260:Female; D016905:Gram-Negative Bacterial Infections / Q000175:diagnosis / Q000382:microbiology* / Q000601:surgery; D006801:Humans; D015948:Keratoplasty, Penetrating; D008875:Middle Aged; D009181:Mycoses / Q000175:diagnosis / Q000382:microbiology* / Q000601:surgery; D012441:Saccharomyces cerevisiae / Q000302:isolation & purification*; D020615:Stenotrophomonas maltophilia / Q000302:isolation & purification*