title: Evolutionarily new sequences expressed in tumors.
abstract: BACKGROUND
  Earlier we suggested the concept of the positive evolutionary role of tumors. According to this concept, tumors provide conditions for the expression of evolutionarily new and/or sleeping genes in their cells. Thus, tumors are considered as evolutionary proving ground or reservoir of expression. To support this concept we have previously characterized in silico and experimentally a new class of human tumor-related transcribed sequences.
  
  
  RESULTS
  In this article we describe results of further studies of previously described tumor-related sequences. The results of molecular phylogeny studies, Southern hybridization experiments and computational comparison with genomes of other species are presented.
  
  
  CONCLUSIONS
  These results suggest that these previously described tumor-related human transcripts are also relatively evolutionarily new.
authors.affiliation: The Biomedical Center, 8 Vyborgskaya St,, St,Petersburg, 194044, Russia. contact@biomed.spb.ru
authors.forename: Andrei P
authors.initials: AP
authors.lastname: Kozlov
authors.forename: Yuri P
authors.initials: YP
authors.lastname: Galachyants
authors.forename: Ilya V
authors.initials: IV
authors.lastname: Dukhovlinov
authors.forename: Nickolai A
authors.initials: NA
authors.lastname: Samusik
authors.forename: Ancha V
authors.initials: AV
authors.lastname: Baranova
authors.forename: Dmitry E
authors.initials: DE
authors.lastname: Polev
authors.forename: Larisa L
authors.initials: LL
authors.lastname: Krukovskaya