DPPH radical scavenging activity of ten natural p-terphenyl derivatives obtained from three edible mushrooms indigenous to China.
The antioxidant activities of ten natural p-terphenyl derivatives, 1-10, obtained from the fruiting bodies of three edible mushrooms (Thelephora ganbajun, Thelephora aurantiotincta, Boletopsis grisea) indigenous to China were evaluated in comparison with BHA ('butylated hydroxyanisole'=(1,1-dimethylethyl)-4-methoxyphenol) and alpha-tocopherol by the DPPH ('1,1-diphenyl-2-picrylhydrazyl'=2,2-diphenyl-1-(2,4,6-trinitrophenyl)hydrazyl) radical-scavenging method. The compounds 1-3 showed significant antioxidant activity. The antioxidant activities of compounds 1-10 and reference compounds followed the order: 2>BHA>1>3>alpha-tocopherol>10>9>6 > 5>8>7>4. The compound 2 exhibited the strongest radical-scavenging activity with an EC(50) value of 0.07 (EC(50)(BHA) 0.09; EC(50)(alpha-tocopherol) 0.25).
Liu
Ji-Kai
JK
Kunming Institute of Botany, the Chinese Academy of Sciences, Kunming 650204, PR China. jkliu@mail.kib.ac.cn
Hu
Lin
L
Dong
Ze-Jun
ZJ
Hu
Qun
Q
D000363:Agaricales / Q000302:isolation & purification; D001713:Biphenyl Compounds / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D002681:China; D016166:Free Radical Scavengers / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D005609:Free Radicals / Q000378:metabolism; D006834:Hydrazines / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D010851:Picrates; D013730:Terphenyl Compounds / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology
D001713:Biphenyl Compounds; D016166:Free Radical Scavengers; D005609:Free Radicals; D006834:Hydrazines; D010851:Picrates; D013730:Terphenyl Compounds; C004931:1,1-diphenyl-2-picrylhydrazyl