title: Principles, developments and applications of on-line coupling of extraction with chromatography.
abstract: On-line coupling of extraction and chromatographic separation allows the whole analysis to be performed in a closed system. On-line systems are particularly useful when the analytes are labile, the amount of sample is limited, or very high sensitivity is required. Many on-line systems have been developed both for liquid and for solid samples. This review discusses the different instruments that have been constructed and the factors that need to be considered in the coupling. Selected illustrative applications are described to illustrate the potential of the on-line systems.
authors.affiliation: University of Helsinki, Department of Chemistry, Laboratory of Analytical Chemistry, P.O. Box 55, FIN-00014 University of Helsinki, Finland. Tuulia.Hyotylainen@helsinki.fi
authors.forename: Tuulia
authors.initials: T
authors.lastname: Hyötyläinen
mesh_terms: D053000:Analytic Sample Preparation Methods / Q000295:instrumentation / Q000379:methods*; D002845:Chromatography / Q000379:methods*; D002849:Chromatography, Gas / Q000295:instrumentation / Q000379:methods; D002853:Chromatography, Liquid / Q000295:instrumentation / Q000379:methods; D025924:Chromatography, Supercritical Fluid / Q000379:methods; D004785:Environmental Pollutants / Q000032:analysis; D008872:Microwaves; D009862:Online Systems / Q000295:instrumentation*; D011312:Pressure; D052616:Solid Phase Extraction / Q000379:methods; D013010:Sonication
chemical_list: D004785:Environmental Pollutants