title: [Q fever endocarditis: a case report].
abstract: Do we bring back the observation of a patient aged of 42 years having a mitro-aortic valvulopathy who present since 3 months a level III dyspnea, a fever to 39 degrees C, a change of the general state and a splenomegaly. To the chest x-ray we note a pulmonary parenchymatous focus. Echocardiography puts in evidence a mitral illness to stenosis predominance and an aortic illness complicated of a graft bacterial with an abscess of the mitro-aortic trigone. Haemocultures were negative and the serology of the Rickettsia was positive. The diagnosis of infective endocarditis to Coxiella Burnetii is kept and is the patient put under Doxycycline 200 mg/j, Hydroxychloroquine 2 cp/j and Ofloxacine 400 mg/j. Will the two first antibiotics be pursued to the 18th month. The patient benefited, after 20 days of three antibiotics therapy, of a duplicate aortic and mitral replacement with simple following.
authors.affiliation: Service de Cardiologie Adultes Hôpital La Rabra, Tunis, Tunisie.
authors.forename: Imen
authors.initials: I
authors.lastname: Fradi
authors.forename: Mohamed Akram
authors.initials: MA
authors.lastname: Drissa
authors.forename: Mehdi
authors.initials: M
authors.lastname: Cheour
authors.forename: Habiba
authors.initials: H
authors.lastname: Drissa
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000627:therapeutic use; D001021:Aortic Valve; D001024:Aortic Valve Stenosis / Q000175:diagnosis / Q000601:surgery; D004318:Doxycycline / Q000008:administration & dosage / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D017548:Echocardiography, Transesophageal; D004697:Endocarditis, Bacterial / Q000150:complications / Q000188:drug therapy / Q000209:etiology*; D004791:Enzyme Inhibitors / Q000008:administration & dosage / Q000627:therapeutic use; D005260:Female; D005500:Follow-Up Studies; D006350:Heart Valve Prosthesis; D019918:Heart Valve Prosthesis Implantation; D006801:Humans; D006886:Hydroxychloroquine / Q000008:administration & dosage / Q000627:therapeutic use; D008943:Mitral Valve; D008944:Mitral Valve Insufficiency / Q000175:diagnosis / Q000601:surgery; D008946:Mitral Valve Stenosis / Q000175:diagnosis / Q000601:surgery; D015242:Ofloxacin / Q000008:administration & dosage / Q000627:therapeutic use; D011778:Q Fever / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D013902:Radiography, Thoracic; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents; D004791:Enzyme Inhibitors; D006886:Hydroxychloroquine; D015242:Ofloxacin; D004318:Doxycycline