title: Suicide rates in the Lundby cohort before and after the introduction of tricyclic antidepressant drugs.
abstract: The Lundby cohort consisting of 3563 subjects was investigated in 1947, 1957, 1972, and 1997. It represents a rural, but gradually urbanized Swedish sample without non-Nordic immigrants and offers an opportunity to study suicide rates before and after the introduction of tricyclic antidepressant drugs in Sweden in 1962. Since then, a fall in suicide rate among depressed individuals was observed, while there was an increase in the overall suicide rate. In fact, in 1977-1992 other psychiatric diagnoses, alcohol disorder included, were more often associated with suicide than depression. No psychiatric or alcohol disorder was registered in 7% of the suicides.
authors.affiliation: Department of Clinical Sciences, Division of Psychiatry, The Lundby Study, Lund University, SE-221 85, Lund, Sweden.
authors.forename: Per
authors.initials: P
authors.lastname: Nettelbladt
authors.forename: Cecilia
authors.initials: C
authors.lastname: Mattisson
authors.forename: Mats
authors.initials: M
authors.lastname: Bogren
authors.forename: Marika
authors.initials: M
authors.lastname: Holmqvist
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000437:Alcoholism / Q000401:mortality; D000929:Antidepressive Agents, Tricyclic / Q000627:therapeutic use*; D015331:Cohort Studies; D003430:Cross-Sectional Studies; D003866:Depressive Disorder / Q000188:drug therapy* / Q000401:mortality*; D005260:Female; D006801:Humans; D015994:Incidence; D008137:Longitudinal Studies; D008297:Male; D001523:Mental Disorders / Q000401:mortality; D008875:Middle Aged; D013405:Suicide / Q000706:statistics & numerical data* / Q000639:trends; D013548:Sweden; D000092864:Suicide Prevention
chemical_list: D000929:Antidepressive Agents, Tricyclic