title: Skin rejuvenation without a scalpel. I. Fillers.
abstract: Fillers are an important tool in the armamentarium of the physician combating aging phenomena. A wide variety of filler substances are now available that meet many, but by far not all, needs in aesthetic medicine. The most commonly used substances now are hyaluronic acid and collagen preparations that have slightly different indications, but collagen requires pre-use testing to rule out inflammatory complications. Poly-L-lactic acid has gained its place in the filling of adipose tissue wasting in HIV-infected patients. Autologous fat is easy to harvest and inject and has virtually no risk of adverse side effects. Permanent fillers may be of advantage but carry the risk of permanent adverse reactions. Skillful combination of different fillers as well as with botulinum toxin injections and other cosmetic procedures may give optimal results.
authors.affiliation: Department of Dermatology, University Medical Centre, The Netherlands. haneke@gmx.net
authors.forename: Eckart
authors.initials: E
authors.lastname: Haneke
mesh_terms: D001672:Biocompatible Materials / Q000008:administration & dosage*; D019274:Botulinum Toxins, Type A / Q000008:administration & dosage; D003094:Collagen / Q000008:administration & dosage; D003357:Cosmetic Techniques; D003879:Dermatologic Agents / Q000008:administration & dosage*; D006801:Humans; D006820:Hyaluronic Acid / Q000008:administration & dosage; D007267:Injections; D009465:Neuromuscular Agents / Q000008:administration & dosage; D015595:Skin Aging
chemical_list: D001672:Biocompatible Materials; D003879:Dermatologic Agents; D009465:Neuromuscular Agents; D006820:Hyaluronic Acid; D003094:Collagen; D019274:Botulinum Toxins, Type A