title: [Role of deep seminal tract imaging in the diagnosis of unilateral agenesis of the vas deferens. Case report of a patient with CFTR gene mutation].
abstract: The authors report the cases of a 35-year-old man with a 4-year history of primary infertility with normal clinical examination and semen parameters. Deep genital tract imaging demonstrated isolated unilateral agenesis of the pelvic portion of the left vas deferens associated with abnormalities of the homolateral seminal vesicle. Molecular analysis of the CFTR gene demonstrated composite heterozygosity with the presence of DeltaF508 / V938G mutations. In the light of this case, the authors recommend urogenital imaging for all men consulting for infertility.
authors.affiliation: Service d'Andrologie, Hôpital Calmette, Lille, France. francois.marcelli@wanadoo.fr
authors.forename: François
authors.initials: F
authors.lastname: Marcelli
authors.forename: Geoffroy
authors.initials: G
authors.lastname: Robin
authors.forename: Valérie
authors.initials: V
authors.lastname: Mitchell
authors.forename: Viviane
authors.initials: V
authors.lastname: Dumur
authors.forename: Philippe
authors.initials: P
authors.lastname: Puech
authors.forename: Laurent
authors.initials: L
authors.lastname: Lemaitre
authors.forename: Jean-Marc
authors.initials: JM
authors.lastname: Rigot
mesh_terms: D000328:Adult; D019005:Cystic Fibrosis Transmembrane Conductance Regulator / Q000235:genetics*; D006801:Humans; D007248:Infertility, Male / Q000235:genetics; D008279:Magnetic Resonance Imaging; D008297:Male; D009154:Mutation; D014649:Vas Deferens / Q000002:abnormalities* / Q000473:pathology*
chemical_list: D019005:Cystic Fibrosis Transmembrane Conductance Regulator