title: [Influence of anxiety in diverse cutaneous diseases].
abstract: BACKGROUND
  The objective of the current study is to determine the levels of anxiety in patients with dermatological diseases compared to healthy subjects and the degree of anxiety in the different cutaneous diseases.
  
  
  METHODS
  It is a descriptive study of a case series where 152 patients are selected, 20 of whom are healthy controls and the other 132 are patients that attend a Dermatology clinic. The patients are divided into 5 groups based on the cutaneous disorder for which they attend the clinic: chronic urticaria, acute urticaria, plaque psoriasis, atopic dermatitis, and a miscellaneous group (includes several diagnoses such as seborrheic keratosis, follow-up of multiple nevi, carcinomas...) where, a priori, anxiety does not influence these disorders. Spielberger State-Trait Anxiety Inventory (STAI) is administered to the participating subjects and the differences in State Anxiety Inventory (SAI) and Trait Anxiety Inventory (TAI) for the different groups are analyzed. Patients were asked to report any stressful event in the six months prior to the appearance of the disease that might have been a trigger, and they were also asked about history of psychiatric disorders or atopy.
  
  
  RESULTS
  We observed significant differences in the means obtained in SAI and TAI in healthy subjects compared to patients. We obtained higher mean scores in SAI in patients diagnosed of atopic dermatitis, that were significant when compared with patients with chronic urticaria or other diseases. Forty-eight percent of patients with psoriasis and 38.89 % of patients with atopic dermatitis report a stressful event in the past six months compared to 11.54% of patients from the group with miscellaneous diseases and, additionally, patients with psoriasis and atopic dermatitis have the highest mean scores in the anxiety tests. Twenty-one percent of the 132 patients with cutaneous diseases report a history of psychiatric disorders, showing statistically significant higher mean scores in STAI.
  
  
  CONCLUSIONS
  The findings show the comorbidity of psychiatric disorders in patients with chronic cutaneous diseases and the high levels of state and trait anxiety, mainly in patients with psoriasis and atopic dermatitis.
authors.affiliation: Hospital Clínico San Carlos, IECP, Madrid, Spain. elena_vargaslaguna@hotmail.com
authors.forename: E
authors.initials: E
authors.lastname: Vargas Laguna
authors.forename: M L
authors.initials: ML
authors.lastname: Peña Payero
authors.forename: A
authors.initials: A
authors.lastname: Vargas Márquez
mesh_terms: D000328:Adult; D001007:Anxiety / Q000453:epidemiology*; D001008:Anxiety Disorders / Q000453:epidemiology; D016022:Case-Control Studies; D015897:Comorbidity; D003876:Dermatitis, Atopic / Q000453:epidemiology / Q000523:psychology; D005260:Female; D006801:Humans; D006969:Hypersensitivity, Immediate / Q000453:epidemiology; D008016:Life Change Events; D008297:Male; D001523:Mental Disorders / Q000453:epidemiology; D008875:Middle Aged; D010555:Personality Inventory; D011565:Psoriasis / Q000453:epidemiology / Q000523:psychology; D011581:Psychological Tests; D011598:Psychoneuroimmunology; D012720:Severity of Illness Index; D012871:Skin Diseases / Q000453:epidemiology / Q000523:psychology*; D013315:Stress, Psychological / Q000453:epidemiology; D013997:Time Factors; D014581:Urticaria / Q000453:epidemiology / Q000523:psychology