Evaluation of peripapillary detachment in pathologic myopia with en face optical coherence tomography.
BACKGROUND
A newly recognized lesion in pathologic myopia is peripapillary detachment of the retinal pigment epithelium (RPE) and retina. Recently introduced en face optical coherence tomography (OCT) provides not only cross-sectional but also coronal scans of the retina, and allows lateral extent visualization and thickness measurement of lesions.


METHODS
Three patients presenting bilateral peripapillary yellow-orange lobulated area in high myopia have been evaluated with fluorescein angiography (FA), indocyanine green angiography (ICGA), en face OCT (OCT/SLO; Ophthalmic Technologies Inc, Toronto, Canada), and Humphrey visual field analyzer.


RESULTS
In all eyes, en face OCT has shown the presence of a peripapillary sub-RPE nonreflective area. The lateral extent of this area was clearly detectable and the measurement of its thickness was obtained. We detected a cleft in the RPE at one edge of the cavitation in two eyes, vascular tractions and vitreoretinal tractions in two eyes, a macular hole with posterior retinal detachment, and small areas of RPE detachment nonconnected with the peripapillary detachment in one eye. In the four eyes presenting a proper central fixation, glaucomatous visual field defects were evident.


CONCLUSIONS
En face OCT has allowed to evaluate the thickness and the lateral extent of the peripapillary detachment. Therefore, its use could be important in determining the size and grading of these lesions at first visit, and to detect minimal changes of width and thickness during follow-up as an alternative to fluorescein angiography.
Forte
R
R
Eye Department, University Federico II, Naples, Italy. raifor@hotmail.com
Pascotto
F
F
Cennamo
G
G
de Crecchio
G
G
D000368:Aged; D005260:Female; D006801:Humans; D008875:Middle Aged; D047728:Myopia, Degenerative / Q000150:complications / Q000473:pathology*; D012163:Retinal Detachment / Q000175:diagnosis* / Q000209:etiology; D012171:Retinal Vessels / Q000473:pathology*; D041623:Tomography, Optical Coherence / Q000379:methods* / Q000592:standards; D058609:Visual Field Tests; D014794:Visual Fields