[The effect of fluctuations of the electric potential on the activity of SAN cells].
The effect of fluctuations of the transmembrane potential on the generation of the action potential has been studied using a computer model of a SAN cell. It was shown that the magnitude of the effect increases with increasing concentration of acetylcholine. The effect is well seen near and after the cessation of spontaneous oscillations. While applying and washing acetylcholine, a hysteresis loop has been observed.
Aliev
R R
RR
D000109:Acetylcholine / Q000494:pharmacology; D000200:Action Potentials; D000818:Animals; D003198:Computer Simulation; D008564:Membrane Potentials / Q000187:drug effects; D008955:Models, Cardiovascular; D011817:Rabbits; D012849:Sinoatrial Node / Q000166:cytology / Q000187:drug effects / Q000502:physiology*
D000109:Acetylcholine