A review of burst generation by trigeminal main sensory neurons.
In this paper, we present evidence that neurons in the dorsal part of the trigeminal main sensory nucleus participate in the patterning of mastication. These neurons have special membrane properties that allow them to generate rhythmical bursts of action potentials in the frequency range of natural mastication even when cut off from synaptic inputs. These properties mature during the third postnatal week in rats at the same time as mastication begins. Finally, we present evidence that a reduction on extracellular calcium concentration is an important step in the initiation of mastication.
Kolta
Arlette
A
Faculté de médecine dentaire, Université de Montréal, Canada. arlette.kolta@umontreal.ca
Brocard
Frédéric
F
Verdier
Dorly
D
Lund
James P
JP
D000200:Action Potentials / Q000502:physiology; D000818:Animals; D000831:Animals, Newborn; D020013:Calcium Signaling; D008409:Mastication / Q000502:physiology*; D009475:Neurons, Afferent / Q000502:physiology*; D018408:Patch-Clamp Techniques; D051381:Rats; D009435:Synaptic Transmission / Q000502:physiology; D014278:Trigeminal Nuclei / Q000502:physiology*