[Two cases of acute renal failure associated with non-fulminant acute hepatitis A].
Hepatitis A is generally regarded as a mild, self-limiting disease of the liver. Acute renal failure has rarely been reported in association with non-fulminant acute hepatitis A. Acute tubular necrosis is the most common form of renal injury in such patients. We recently experienced two cases of hepatitis A in which acute renal failure occurred early in the course of the illness and had a clinical course suggestive of acute tubular necrosis. In both patients, the clinical course of renal dysfunction was almost parallel to that of hepatic dysfunction. Hemodialysis was performed in patient 1 because of severe uremia despite maintaining urine output more than 2,000 mL per day. On the other hand, hemodialysis was not performed in patient 2 who showed a rapid recovery of renal dysfunction. The renal biopsy of patient 1 demonstrated typical findings of acute tubular necrosis on microscopy.
Kim
Sung Eun
SE
Department of Internal Medicine, Kangdong Sacred Heart Hospital, Hallym University College of Medicine, Gangdong-Gu, Seoul, Korea.
Kim
Soo Jin
SJ
Kim
Hyoung Su
HS
Kim
Hee Sun
HS
Nam
Eun Sook
ES
Lee
Sang Kyu
SK
Shin
Su Rin
SR
Kim
Hak Yang
HY
D000208:Acute Disease; D058186:Acute Kidney Injury / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D000328:Adult; D006506:Hepatitis A / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D008297:Male; D006435:Renal Dialysis / Q000379:methods