Non-invasive imaging of osteoclast activity via near-infrared cathepsin-K activatable optical probe.
Kozloff
K M
KM
Center for Molecular Imaging Research, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA. kkozloff@partmers.org
Quinti
L
L
Tung
C
C
Weissleder
R
R
Mahmood
U
U
D000818:Animals; D001842:Bone and Bones / Q000378:metabolism; D056657:Cathepsin K; D002403:Cathepsins / Q000378:metabolism; D003952:Diagnostic Imaging / Q000379:methods; D005260:Female; D005456:Fluorescent Dyes / Q000378:metabolism; D051379:Mice; D008807:Mice, Inbred BALB C; D055095:Optics and Photonics; D010010:Osteoclasts / Q000166:cytology / Q000378:metabolism*; D010052:Ovariectomy; D041622:Tomography, Optical / Q000379:methods*
D005456:Fluorescent Dyes; D002403:Cathepsins; D056657:Cathepsin K; C534132:Ctsk protein, mouse