Transient severe metastatic calcification in acute renal failure.
Metastatic calcification, a known complication of prolonged end-stage renal disease, is herein described for the first time in a 10-month-old boy with acute renal failure, manifesting as a painful and swollen arm. Imaging revealed diffuse calcification and technetium-99 methylene diphosphonate (99Tc-MDP) uptake around the humerus and axilla. Calcium and vitamin D restriction, followed by intravenous administration of sodium thiosulfate caused a full symptomatic, radio- and scintigraphic improvement.
Landau
Daniel
D
Department of Pediatrics A, Soroka University Medical Center, P.O. Box 151, Beer-Sheva 84101, Israel. ldaniel@bgu.ac.il
Krymko
Hanna
H
Shalev
Hanna
H
Agronovich
Svetlana
S
D058186:Acute Kidney Injury / Q000150:complications* / Q000628:therapy; D002114:Calcinosis / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D006801:Humans; D007223:Infant; D008297:Male; D019275:Radiopharmaceuticals; D013669:Technetium Tc 99m Medronate
D019275:Radiopharmaceuticals; D013669:Technetium Tc 99m Medronate