title: Membranoproliferative glomerulonephritis in a patient with Wilson's disease.
abstract: Wilson's disease is an autosomal recessive disorder of hepatobiliary copper metabolism. Glomerular diseases can ensue during the course of Wilson's disease and membranous nephropathy is the eventual pathology in the majority of these cases. Membranoproliferative glomerulonephritis (MPGN) has rarely been reported in patients with Wilson's disease. Further, in this report, we present a patient with Wilson's disease who had developed MPGN during follow-up due to D-penicillamine therapy. This case is presented to draw attention to the rare association of Wilson's disease and MPGN and to discuss the possible underlying causes.
authors.affiliation: Department of Pediatric Nephrology, Ankara University Medical School, Ankara, Turkey. zbozcakar@yahoo.com
authors.forename: Z Birsin
authors.initials: ZB
authors.lastname: Ozçakar
authors.forename: Mesiha
authors.initials: M
authors.lastname: Ekim
authors.forename: Arzu
authors.initials: A
authors.lastname: Ensari
authors.forename: Zarife
authors.initials: Z
authors.lastname: Kuloglu
authors.forename: Selçuk
authors.initials: S
authors.lastname: Yüksel
authors.forename: Banu
authors.initials: B
authors.lastname: Acar
authors.forename: Ceyda
authors.initials: C
authors.lastname: Kirsaçlioglu
authors.forename: Aydan
authors.initials: A
authors.lastname: Kansu
authors.forename: Fatoş
authors.initials: F
authors.lastname: Yalçinkaya
authors.forename: Nurten
authors.initials: N
authors.lastname: Girgin
mesh_terms: D000293:Adolescent; D002614:Chelating Agents / Q000008:administration & dosage / Q000009:adverse effects*; D015432:Glomerulonephritis, Membranoproliferative / Q000139:chemically induced* / Q000473:pathology; D006527:Hepatolenticular Degeneration / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D006801:Humans; D008297:Male; D010396:Penicillamine / Q000008:administration & dosage / Q000009:adverse effects*
chemical_list: D002614:Chelating Agents; D010396:Penicillamine