Quantitative electroencephalographic profiles for children with autistic spectrum disorder.
The present study examined quantitative electroencephalographic (QEEG) profile for children with autistic spectrum disorder (ASD). Five-minute QEEG data were obtained from 90 normal controls (NCs) and 66 children with ASD. Spectrum analyses revealed that ASD children showed significantly less relative alpha and more relative delta than NC. Specifically, 26% of ASD children and 2% of NCs showed 1.5 SDs of relative alpha below the normative mean. Children with this QEEG profile had 17 times the risk of having ASD than those without such a profile. Sensitivity and specificity of relative alpha were 91% and 73%, respectively. Split-half cross-validation yielded a sensitivity of 76%.
Chan
Agnes S
AS
Department of Psychology, Chinese University of Hong Kong, Shatin, Hong Kong, China. aschan@psy.cuhk.edu.hk
Sze
Sophia L
SL
Cheung
Mei-Chun
MC
D000293:Adolescent; D001931:Brain Mapping; D002648:Child; D002659:Child Development Disorders, Pervasive / Q000503:physiopathology*; D004569:Electroencephalography; D005260:Female; D006801:Humans; D008297:Male; D016017:Odds Ratio; D013057:Spectrum Analysis