[Clinical observation on Qingling Dingxuan Decoction in treating vertigo cause by insufficient blood-supply of ventebrobasilar artery].
OBJECTIVE
To observe the therapeutic effect of Qingling Dingxuan Decoction (QDD) on vertigo caused by insufficient blood-supply of ventebrobasilar artery (IBVA).


METHODS
Thirty-nine patients were divided into the flunarizine group (n=19) and the QDD group (n=20) treated with respective medicine on the base of routine treatment with Chinese and Western medicine. The clinical efficacy and recurrent rate were observed and compared.


RESULTS
Compared with those in the flunarizine group, clinical curative effect was better, recurrent rate lower, symptom score higher, hemorheological parameters and transcranial doppler indexes were improved more significant in the QDD group (P < 0.01 or P < 0.05).


CONCLUSIONS
QDD had obvious therapeutic effect on IBVA. Improvement of microcirculation and reduction of blood viscosity may be one of the therapeutical mechanisms.
Zheng
Guo-qing
GQ
Neurology Center, The Second Affiliated Hospital of Wenzhou Medical College, Zhejing. gq_zheng@sina.com
Wang
Yan
Y
Pan
Juan
J
D000328:Adult; D000368:Aged; D001809:Blood Viscosity / Q000187:drug effects; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D018056:Hemorheology / Q000187:drug effects; D006801:Humans; D008297:Male; D008833:Microcirculation / Q000187:drug effects; D008875:Middle Aged; D008517:Phytotherapy; D011446:Prospective Studies; D017585:Ultrasonography, Doppler, Transcranial; D014715:Vertebrobasilar Insufficiency / Q000150:complications / Q000000981:diagnostic imaging / Q000188:drug therapy*; D014717:Vertigo / Q000188:drug therapy* / Q000209:etiology
D004365:Drugs, Chinese Herbal; C527659:qingling dingxuan