Can alcohol-based hand-rub solutions cause you to lose your driver's license? Comparative cutaneous absorption of various alcohols.
We assessed cutaneous ethanol (ETOH) and isopropanol (ISOP) absorption after intensive (30 times per h) use of alcohol-based hand-rub solutions by healthcare workers (HCWs). ETOH was detectable in the breath of 6/20 HCWs (0.001 to 0.0025%) at 1 to 2 min postexposure and in the serum of 2/20 HCWs at 5 to 7 min postexposure. Serum ISOP levels were unrecordable at all time points.
Brown
T L
TL
Infectious Diseases Department, Austin Health, Studley Road, Heidelberg, Victoria 3084, Australia.
Gamon
S
S
Tester
P
P
Martin
R
R
Hosking
K
K
Bowkett
G C
GC
Gerostamoulos
D
D
Grayson
M L
ML
D019840:2-Propanol / Q000493:pharmacokinetics; D000287:Administration, Topical; D000328:Adult; D000368:Aged; D000891:Anti-Infective Agents, Local / Q000008:administration & dosage / Q000097:blood* / Q000493:pharmacokinetics*; D002849:Chromatography, Gas; D000431:Ethanol / Q000008:administration & dosage / Q000097:blood* / Q000493:pharmacokinetics*; D005260:Female; D006282:Health Personnel; D006801:Humans; D008297:Male; D008875:Middle Aged; D012869:Skin Absorption
D000891:Anti-Infective Agents, Local; D000431:Ethanol; D019840:2-Propanol