title: Experience with conservative strategy of uterine artery embolization in the treatment of placenta percreta in the first trimester of pregnancy.
abstract: OBJECTIVE
  There is little prospective experience in the conservative treatment of placenta percreta during the first trimester in order to preserve uterine fertility. We describe herein our experience with uterine artery embolization (UAE) in the management of placenta percreta at 9 weeks of gestation.
  
  
  METHODS
  A 36-year-old woman, gravida 3, para 1, was referred for ultrasonographic evaluation because of suspected molar pregnancy due to persistent vaginal spotting at 9 weeks of gestation. A Grade 3+ lacunar flow pattern with multiple bizarre and large irregular sonolucent spaces were observed. Color Doppler imaging revealed extensive turbulent lacunar blood flow perfusing throughout the whole surrounding uteroplacental tissues and fetus. The patient was informed of the situation and she had a strong desire to avoid surgery. Conservative management with bilateral UAE was performed using polyvinyl alcohol particles to promote involution and shedding of the abnormally adherent placenta. However, an unsatisfactory vessel-occluding effect caused by extensive collateral supply was still detected after repeated UAE. We, therefore, performed hysterectomy, and the patient had an uneventful postoperative course.
  
  
  CONCLUSIONS
  The efficacy and complications of UAE as a therapeutic modality for the conservative management of invasive placentation in the first trimester of pregnancy are not clear, as this is the first report of its kind. However, although UAE had failed in this case, it may still be a useful procedure as a prophylactic measure before surgical intervention, and hysterectomy can also be performed for better control of operative hemorrhage.
authors.affiliation: Department of Obstetrics and Gynecology, Taichung Veterans General Hospital, Chung Shan Medical University, Taiwan.
authors.forename: Shih-Hui
authors.initials: SH
authors.lastname: Tseng
authors.forename: Chia-Hui
authors.initials: CH
authors.lastname: Lin
authors.forename: Jen I
authors.initials: JI
authors.lastname: Hwang
authors.forename: Wei-Che
authors.initials: WC
authors.lastname: Chen
authors.forename: Esther Shih-Chu
authors.initials: ES
authors.lastname: Ho
authors.forename: Min-Min
authors.initials: MM
authors.lastname: Chou
mesh_terms: D000328:Adult; D001158:Arteries; D004621:Embolization, Therapeutic; D005260:Female; D005865:Gestational Age; D006801:Humans; D007044:Hysterectomy; D010921:Placenta Accreta / Q000628:therapy*; D011247:Pregnancy; D011261:Pregnancy Trimester, First; D019233:Retreatment; D017211:Treatment Failure; D014599:Uterus / Q000098:blood supply*