Homing sweet homing: odyssey of hematopoietic stem cells.
The lineage relationship between the blood cells found in the developmentally successive hematopoietic organs has remained elusive. In this issue of Immunity, Murayama et al. (2006) track the migration of nascent hematopoietic stem cells in zebrafish from their site of origin to a newly described intermediate location.
Burns
Caroline Erter
CE
Stem Cell Program and Division of Hematology/Oncology, Children's Hospital Boston and Dana Farber Cancer Institute, Howard Hughes Medical Institute, Harvard Stem Cell Institute, Harvard Medical School, Boston, Massachusetts 02115, USA.
Zon
Leonard I
LI
D000818:Animals; D019070:Cell Lineage; D002634:Chemotaxis, Leukocyte / Q000276:immunology*; D006410:Hematopoiesis / Q000502:physiology*; D006412:Hematopoietic Stem Cells; D015027:Zebrafish