title: Fighting fly genes.
abstract: Fighting by organisms such as mice and Drosophila provides model systems for investigating the genetic basis of aggression. Recent experiments to dissect male aggressive behaviour in Drosophila melanogaster, using gene expression analysis of selected lines followed by mutant analysis, have identified new candidate genes associated with male aggression, including one strong candidate that encodes a cytochrome P450 enzyme. Here, we describe the study of aggressive behaviour in flies and explore the possibility that cytochrome P450 is involved in aggression.
authors.affiliation: Centre of Environmental Stress and Adaptation Research, Department of Genetics, The University of Melbourne, Victoria 3010, Australia.
authors.forename: Charles
authors.initials: C
authors.lastname: Robin
authors.forename: Phillip J
authors.initials: PJ
authors.lastname: Daborn
authors.forename: Ary A
authors.initials: AA
authors.lastname: Hoffmann
mesh_terms: D000378:Agonistic Behavior; D000818:Animals; D003577:Cytochrome P-450 Enzyme System / Q000235:genetics / Q000502:physiology; D004331:Drosophila melanogaster / Q000235:genetics*; D017344:Genes, Insect; D008297:Male; D008954:Models, Biological
chemical_list: D003577:Cytochrome P-450 Enzyme System