title: Detection of hexamethonium-perchlorate association complexes using NACE-MS.
abstract: Perchlorate (ClO(4) (+)) and other chlorine oxide anions were observed to complex weakly with hexamethonium (1,6-bis-(trimethylammonium)-hexane) in both aqueous and polar nonaqueous solvents. The resultant positively charged complexes were resolved by NACE using 2-propanol/acetone electrolytes prior to mass spectrometric detection using an Agilent(3D)CE system coupled to a Bruker Esquire 3000+ quadrupole IT mass detector. Using electrokinetic injection, the method detection limit for perchlorate in nonaqueous media was 10 microg/L. The isotope patterns due to the presence of (35)Cl and (37)Cl in complex mass spectra allowed for unambiguous identification of perchlorate, chlorate (ClO(3) (+)), chlorite (ClO(2) (+)), and chloride (Cl(+)) in photoreaction samples.
authors.affiliation: Biotechnology Research Institute, National Research Council of Canada, Montreal PQ, Canada.
authors.forename: Carl A
authors.initials: CA
authors.lastname: Groom
authors.forename: Jalal
authors.initials: J
authors.lastname: Hawari
mesh_terms: D002704:Chlorates / Q000032:analysis; D002712:Chlorides / Q000032:analysis; D002713:Chlorine / Q000737:chemistry*; D004573:Electrolytes / Q000737:chemistry; D019075:Electrophoresis, Capillary; D018738:Hexamethonium / Q000032:analysis* / Q000737:chemistry; D007554:Isotopes / Q000737:chemistry; D010472:Perchlorates / Q000032:analysis* / Q000737:chemistry; D021241:Spectrometry, Mass, Electrospray Ionization
chemical_list: D002704:Chlorates; D002712:Chlorides; D004573:Electrolytes; D007554:Isotopes; D010472:Perchlorates; D018738:Hexamethonium; D002713:Chlorine; C494474:perchlorate; C001599:chlorite