Erythrocyte ion transport in rats subjected to acute and chronic hypobaric hypoxia.
Our study addresses selected parameters of rat erythrocyte ion transport (Na(+)-K(+) pump, Na(+)-K(+)-2Cl- cotransport, and passive cation fluxes) after acute or chronic hypoxia exposure. We did not find any significant change of ion transport after acute hypoxia. However, chronic hypoxia could modify ion transport because the affinity of Na(+)-K(+) pump for intracellular Na(+) seems to be decreased.
Rauchová
H
H
Institute of Physiology, Academy of Sciences of the Czech Republic, Prague, Czech Republic. rauchova@biomed.cas.cz
Vokurková
M
M
Dobesová
Z
Z
Kunes
J
J
Zicha
J
J
D000208:Acute Disease; D000367:Age Factors; D000375:Aging / Q000378:metabolism*; D000531:Altitude; D000818:Animals; D002908:Chronic Disease; D004912:Erythrocytes / Q000378:metabolism*; D000860:Hypoxia / Q000378:metabolism*; D017136:Ion Transport; D011188:Potassium / Q000378:metabolism*; D051381:Rats; D017208:Rats, Wistar; D012964:Sodium / Q000378:metabolism*; D028021:Sodium-Potassium-Chloride Symporters / Q000378:metabolism; D000254:Sodium-Potassium-Exchanging ATPase / Q000378:metabolism
D028021:Sodium-Potassium-Chloride Symporters; D012964:Sodium; D000254:Sodium-Potassium-Exchanging ATPase; D011188:Potassium