title: Randomized effectiveness study of four therapeutic strategies for TMJ closed lock.
abstract: For individuals with temporomandibular joint (TMJ) disc displacement without reduction with limited mouth opening (closed lock), interventions vary from minimal treatment to surgery. In a single-blind trial, 106 individuals with TMJ closed lock were randomized among medical management, rehabilitation, arthroscopic surgery with post-operative rehabilitation, or arthroplasty with post-operative rehabilitation. Evaluations at baseline, 3, 6, 12, 18, 24, and 60 months used the Craniomandibular Index (CMI) and Symptom Severity Index (SSI) for jaw function and TMJ pain respectively. Using an intention-to-treat analysis, we observed no between-group difference at any follow-up for CMI (p > or = 0.33) or SSI (p > or = 0.08). Both outcomes showed within-group improvement (p < 0.0001) for all groups. The findings of this study suggest that primary treatment for individuals with TMJ closed lock should consist of medical management or rehabilitation. The use of this approach will avoid unnecessary surgical procedures.
authors.affiliation: University of Minnesota School of Dentistry, Department of Diagnostic and Biological Sciences, Minneapolis, MN 55455, USA. schif001@umn.edu
authors.forename: E L
authors.initials: EL
authors.lastname: Schiffman
authors.forename: J O
authors.initials: JO
authors.lastname: Look
authors.forename: J S
authors.initials: JS
authors.lastname: Hodges
authors.forename: J Q
authors.initials: JQ
authors.lastname: Swift
authors.forename: K L
authors.initials: KL
authors.lastname: Decker
authors.forename: K M
authors.initials: KM
authors.lastname: Hathaway
authors.forename: R B
authors.initials: RB
authors.lastname: Templeton
authors.forename: J R
authors.initials: JR
authors.lastname: Fricton
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D001178:Arthroplasty; D001182:Arthroscopy; D003376:Counseling; D005500:Follow-Up Studies; D006801:Humans; D004204:Joint Dislocations / Q000188:drug therapy / Q000601:surgery / Q000628:therapy*; D008775:Methylprednisolone / Q000627:therapeutic use; D008875:Middle Aged; D017090:Occlusal Splints; D026741:Physical Therapy Modalities; D012720:Severity of Illness Index; D016037:Single-Blind Method; D019224:Temporomandibular Joint Disc / Q000473:pathology* / Q000601:surgery; D013705:Temporomandibular Joint Disorders / Q000188:drug therapy / Q000601:surgery / Q000628:therapy*; D016896:Treatment Outcome
chemical_list: D000893:Anti-Inflammatory Agents; D000894:Anti-Inflammatory Agents, Non-Steroidal; D008775:Methylprednisolone