Immune reconstitution inflammatory syndrome presenting as sinusitis with inflammatory pseudotumor in an HIV-infected patient: a case report and review of the literature.
Immune reconstitution inflammatory syndrome (IRIS) encompasses a variety of conditions that occur among HIV-infected patients in a temporal relationship with increases in CD4 cell count as a result of highly active antiretroviral therapy (HAART). Most conditions associated with IRIS are infectious. Malignancies, such as Kaposi's sarcoma, have also been reported. We report a case of sinusitis with presumptive inflammatory pseudotumor as a manifestation of IRIS that occurred 20 weeks after the initiation of HAART.
Chan-Tack
Kirk M
KM
Institute of Human Virology, University of Maryland School of Medicine, 725 West Lombard Street, UMBI, N540, Baltimore, Maryland 21201, USA. kchan@medicine.umaryland.edu
Chengappa
K Savitha
KS
Wolf
Jeffrey S
JS
Kao
Grace F
GF
Reisler
Ronald B
RB
D017088:AIDS-Related Opportunistic Infections / Q000473:pathology*; D000328:Adult; D023241:Antiretroviral Therapy, Highly Active / Q000009:adverse effects*; D018791:CD4 Lymphocyte Count; D006104:Granuloma, Plasma Cell / Q000150:complications / Q000503:physiopathology*; D015658:HIV Infections / Q000188:drug therapy*; D006801:Humans; D008297:Male; D012852:Sinusitis / Q000139:chemically induced* / Q000175:diagnosis / Q000473:pathology