title: [Oxidant stress in the pathogenesis of multiple sclerosis].
abstract: The problem of pathogenesis of multiple sclerosis is of great importance in modern neurology and its solution allows to determine a pathogenetic approach to treatment of this severe disease. Parameters of intensification of lipid peroxidation and indices of the state of enzymatic and non-enzymatic patterns in antioxidant defense system in different clinical forms and at different stages of MS course have been analyzed. The data obtained confirm the presence of oxidant stress in the development of pathological process in MS.
authors.forename: M A
authors.initials: MA
authors.lastname: Lutskiĭ
authors.forename: I E
authors.initials: IE
authors.lastname: Esaulenko
mesh_terms: D018450:Disease Progression; D006801:Humans; D008954:Models, Biological; D009103:Multiple Sclerosis / Q000503:physiopathology*; D018384:Oxidative Stress / Q000502:physiology*