Molecular boxes on a molecular printboard: encapsulation of anionic dyes in immobilized dendrimers.
Fifth-generation poly(propylene imine) dendrimers, modified with 64 apolar adamantyl groups, have been immobilized on cyclodextrin host monolayers ("molecular printboards") on glass by supramolecular microcontact printing. The immobilized dendrimers retain their guest-binding properties and function as "molecular boxes" that can be filled with fluorescent dye molecules from solution. Alternatively, part of the immobilized dendrimers were filled with dye molecules by cross-microcontact printing while the remaining, empty dendrimers were filled with a different dye from solution, resulting in alternating patterns of dye molecules. In addition, we demonstrate that encapsulation of dyes in immobilized dendrimers is reversible: immobilized molecular boxes can be filled with a dye, emptied, and subsequently refilled with a different dye.
Onclin
Steffen
S
Laboratory of Supramolecular Chemistry and Technology, MESA+Institute for Nanotechnology, University of Twente, P. O. Box 217, 7500 AE Enschede, The Netherlands.
Huskens
Jurriaan
J
Ravoo
Bart Jan
BJ
Reinhoudt
David N
DN
D001709:Biotechnology / Q000379:methods; D004396:Coloring Agents / Q000737:chemistry*; D003505:Cyclodextrins / Q000737:chemistry; D050091:Dendrimers / Q000737:chemistry*; D016503:Drug Delivery Systems / Q000379:methods; D019793:Fluorescein / Q000494:pharmacology; D005898:Glass / Q000737:chemistry; D018613:Microscopy, Confocal; D008956:Models, Chemical; D008968:Molecular Conformation; D015394:Molecular Structure; D049329:Nanostructures; D036103:Nanotechnology / Q000379:methods*; D011108:Polymers; D012395:Rose Bengal / Q000494:pharmacology
D004396:Coloring Agents; D003505:Cyclodextrins; D050091:Dendrimers; D011108:Polymers; D012395:Rose Bengal; D019793:Fluorescein