Two novel trimeric resveratrol derivatives from Cotylelobium lanceolatum.
Two new resveratrol (= 5-[(E)-2-(4-hydroxyphenyl)ethenyl]benzene-1,3-diol) trimers, cotylelophenols A (1) and B (2), were isolated from the stem of Cotylelobium lanceolatum (Dipterocarpaceae), together with ten known resveratrol oligomers (3-12). The structures of the isolates were established on the basis of spectroscopic analyses, including a detailed NMR spectroscopic investigation of 1 under different conditions. Compound 1 is the first resveratrol trimer with a rearranged 4-hydroxyphenyl group. Four possible biogenetic pathways towards resveratrol oligomers are proposed (Scheme).
Ito
Tetsuro
T
Gifu Prefectural Institute of Health and Environmental Sciences, 1-1 Naka-fudogaoka, Kakamigahara 504-0838, Japan. zvn00510@nifty.ne.jp
Ali
Zulfiqar
Z
Furusawa
Miyuki
M
Iliya
Ibrahim
I
Tanaka
Toshiyuki
T
Nakaya
Ken-ichi
K
Murata
Jin
J
Darnaedi
Dedy
D
Oyama
Masayoshi
M
Iinuma
Munekazu
M
D020448:Ericales / Q000737:chemistry*; D015394:Molecular Structure; D000077185:Resveratrol; D013267:Stilbenes / Q000737:chemistry*
D013267:Stilbenes; D000077185:Resveratrol