Mechanical properties and biological behavior of carbon nanotube/polycarbosilane composites for implant materials.
Multiwalled carbon nanotube/polycarbosilane (MWCNT/PCS) composites were fabricated by the spark plasma sintering (SPS) method. The MWCNT/PCS composites consisted of MWCNTs and nanosized SiC particles pyrolyzed from PCS and possessing good mechanical properties for bone tissue repair or dental implantation. The MWCNT/PCS composites were implanted in the subcutaneous tissue and femur of rats at 1 and 4 weeks after implantation. Histological investigations showed that there was little inflammatory response in the subcutaneous tissue, and newly formed bone tissue was observed in the femur. These results indicated that the MWCNT/PCS composite had little prophlogistic effect and good osteoconductivity. The study suggested the possibility that the MWCNT/PCS composite could be a candidate bone-substitute and dental-implant material in the future.
Wang
Wei
W
Graduate School of Dental Medicine, Hokkaido University, Sapporo 060-8586, Japan. ww1120@den.hokudai.ac.jp
Watari
Fumio
F
Omori
Mamoru
M
Liao
Susan
S
Zhu
Yuhe
Y
Yokoyama
Atsuro
A
Uo
Motohiro
M
Kimura
Hisamichi
H
Ohkubo
Akira
A
D000818:Animals; D001672:Biocompatible Materials / Q000737:chemistry* / Q000494:pharmacology; D018786:Bone Substitutes / Q000737:chemistry* / Q000494:pharmacology; D015921:Dental Implants; D008422:Materials Testing; D019563:Mechanics; D008855:Microscopy, Electron, Scanning; D046529:Microscopy, Electron, Transmission; D053761:Nanocomposites / Q000737:chemistry*; D037742:Nanotubes, Carbon / Q000737:chemistry*; D051381:Rats; D011919:Rats, Inbred Strains; D012821:Silanes / Q000737:chemistry
D001672:Biocompatible Materials; D018786:Bone Substitutes; D015921:Dental Implants; D037742:Nanotubes, Carbon; D012821:Silanes; C504072:carbosilane