title: Sulfated alkenes from the echinus Temnopleurus hardwickii.
abstract: Three new sulfated alkenes (1-3), trimethylammonium (5R)-5,9-dimethyl-(3E)-3,8-decadienyl-1-sulfate, dimethylammonium (5R)-5,9-dimethyl-(3E)-3,8-decadienyl-1-sulfate, and 2'-methyl-4'-oxobutan-2-ylammonium (5R)-5,9-dimethyl-(3E)-3,8-decadienyl-1-sulfate, were isolated from an echinoderm, Temnopleurus hardwickii. Their structures were elucidated by spectral analysis and chemical degradation methods.
authors.affiliation: Key Laboratory of Marine Drugs, Chinese Ministry of Education, Institute of Marine Drugs and Food, Ocean University of China, Qingdao 266003, People's Republic of China.
authors.forename: Li
authors.initials: L
authors.lastname: Chen
authors.forename: Yuchun
authors.initials: Y
authors.lastname: Fang
authors.forename: Xiaodong
authors.initials: X
authors.lastname: Luo
authors.forename: Hongping
authors.initials: H
authors.lastname: He
authors.forename: Tianjiao
authors.initials: T
authors.lastname: Zhu
authors.forename: Hongbing
authors.initials: H
authors.lastname: Liu
authors.forename: Qianqun
authors.initials: Q
authors.lastname: Gu
authors.forename: Weiming
authors.initials: W
authors.lastname: Zhu
mesh_terms: D000475:Alkenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D000818:Animals; D000970:Antineoplastic Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D002681:China; D004354:Drug Screening Assays, Antitumor; D004447:Echinodermata / Q000737:chemistry*; D006801:Humans; D020128:Inhibitory Concentration 50; D007941:Leukemia P388; D051379:Mice; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D013463:Sulfuric Acid Esters / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
chemical_list: C516407:2'-methyl-4'-oxobutan-2-ylammonium(5R)-5,9-dimethyl-(3E)-3,8-decadienyl-1-sulfate; D000475:Alkenes; D000970:Antineoplastic Agents; D013463:Sulfuric Acid Esters; C516406:dimethylammonium (5R)-5,9-dimethyl-(3E)-3,8-decadienyl-1-sulfate; C516405:trimethylammonium (5R)-5,9-dimethyl-(3E)-3,8-decadienyl-1-sulfate