New phenolic constituents from Balanophora polyandra with radical-scavenging activity.
The 80% acetone extract of Balanophora polyandra Griff. (Balanophoraceae) was found to exhibit high radical-scavenging activity (SC(50)=14.48 mug/ml) towards 1,1-diphenyl-2-picrylhydrazyl (DPPH) radicals. Further chemical investigation led the isolation of two new hydrolysable tannins, balapolyphorins A (1) and B (2), together with 20 known phenolic compounds (3-22). Their structures were established by detailed spectroscopic analysis, and the radical-scavenging properties of all isolated compounds were determined by DPPH assay.
Wang
Kai-Jin
KJ
State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, PR China.
Zhang
Ying-Jun
YJ
Yang
Chong-Ren
CR
D000096:Acetone / Q000737:chemistry; D031111:Balanophoraceae / Q000378:metabolism*; D001713:Biphenyl Compounds / Q000737:chemistry; D016166:Free Radical Scavengers / Q000737:chemistry*; D005609:Free Radicals; D006834:Hydrazines / Q000737:chemistry; D047348:Hydrolyzable Tannins / Q000138:chemical synthesis / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D008956:Models, Chemical; D019800:Phenol / Q000737:chemistry*; D010851:Picrates; D010936:Plant Extracts / Q000737:chemistry* / Q000378:metabolism; D013053:Spectrophotometry / Q000379:methods; D013056:Spectrophotometry, Ultraviolet; D013634:Tannins / Q000737:chemistry
D001713:Biphenyl Compounds; D016166:Free Radical Scavengers; D005609:Free Radicals; D006834:Hydrazines; D047348:Hydrolyzable Tannins; D010851:Picrates; D010936:Plant Extracts; D013634:Tannins; C517256:balapolyphorin A; C517255:balapolyphorin B; D000096:Acetone; D019800:Phenol; C004931:1,1-diphenyl-2-picrylhydrazyl