title: Obstetric cerebral venous thrombosis.
abstract: Pregnancy and puerperium are most prevalent prothrombotic states leading to cerebral venous thrombosis. Likelihood of stroke to be of venous origin is greater in stroke associated with pregnancy compared to stroke unrelated to pregnancy. Pregnancy induces several changes in coagulation system, which persists at least during early puerperium, rendering it a prothrombotic state. Hypercoaguability worsens further after delivery as a result of volume depletion and trauma. During puerperium additional risk factors include infection and instrumental delivery or Caesarean section. The management follows general rules as for the venous thrombosis unrelated to pregnancy, however the prognosis is different.
authors.affiliation: Neurology Section, Department of Medicine, The Aga Khan University, Karachi.
authors.forename: Bhojo A
authors.initials: BA
authors.lastname: Khealani
authors.forename: Uzma U
authors.initials: UU
authors.lastname: Mapari
authors.forename: Rozina
authors.initials: R
authors.lastname: Sikandar
mesh_terms: D002550:Cerebral Veins / Q000473:pathology*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D020767:Intracranial Thrombosis / Q000175:diagnosis / Q000209:etiology*; D009774:Obstetrics; D011247:Pregnancy; D011248:Pregnancy Complications; D011379:Prognosis; D012307:Risk Factors; D012851:Sinus Thrombosis, Intracranial / Q000175:diagnosis / Q000209:etiology*; D020246:Venous Thrombosis / Q000175:diagnosis / Q000209:etiology*