title: [A case of atypical malignant hyperthermia which presented a typical rise in Ca-induced Ca release after the operation].
abstract: A 61-year-old man showed clinical findings which suggest atypical malignant hyperthermia after pancreatoduodenectomy. He showed no abnormal findings in preoperative examinations. General anesthesia was induced with thiopental, fentanyl, and vecuronium, and epidural anesthesia was also used for the perioperative management. The surgery went on uneventfully and the patient returned to the ward. The laboratory data after the surgery showed extremely high creatine kinase and myoglobin. The patient's body temperature rose up and showed rigidity. We suspected atypical malignant hyperthermia and began its treatment. Four months later, we performed muscle biopsy and Ca-induced Ca release (CICR) test, which presented a typical rising pattern. This is the first case of malignant hyperthermia which occurred after the surgery and accompanied by a typical rise in CICR.
authors.affiliation: Department of Anesthesiology, Yokohama Nanbu Hospital, Yokohama.
authors.forename: Yoshimi
authors.initials: Y
authors.lastname: Akashi
authors.forename: Rie
authors.initials: R
authors.lastname: Sato
authors.forename: Minako
authors.initials: M
authors.lastname: Sato
authors.forename: Yasuto
authors.initials: Y
authors.lastname: Tanito
authors.forename: Hiromasa
authors.initials: H
authors.lastname: Suzuki
mesh_terms: D002118:Calcium / Q000378:metabolism*; D006801:Humans; D008297:Male; D008305:Malignant Hyperthermia / Q000175:diagnosis / Q000378:metabolism*; D008875:Middle Aged
chemical_list: D002118:Calcium