title: [Trial of isolation of sick house syndrome and unclassified multiple chemical sensitivities--Definition of sick house syndrome, and symptoms].
abstract: OBJECTIVE
  This study was designed to clarify the definition of sick house syndrome (SHS).
  
  
  METHODS
  SHS was defined based on the disease related to habitation as follows. 1. The cause of the onset of a disease relates to house. 2. Symptoms appear within house. 3. Symptoms will be less serious or disappear if patient away from house. 4. If patient goes into house, symptoms will appear repeatedly. When it corresponded to all above, it was defined to SHS, and it classified as MCS (multiple chemical sensitivities) without above conditions. Even if SHS is isolated from similar disease completely, characteristic symptoms of MCS are hard to be detected because MCS are combination of two or more diseases. Based on this working hypothesis, the logistic regression by setting MCS as reference was performed so that characteristic symptoms of SHS show odds ratios with exceeding one.
  
  
  RESULTS
  The odds ratios with more than two of characteristic symptoms in SHS were "nausea or vomiting" "Troublesome in everything" and the causative substances to which symptoms get worse was "The smell of a perfume and cosmetics". Characteristic symptoms of an allergy disease were detected by comparison with the allergic conjunctivitis, allergic rhinitis, and bronchial asthma, respectively.
  
  
  CONCLUSIONS
  These results showed that the classification method was appropriate. This definition is not fundamentally differed from the definition of the sick-building syndrome of WHO.
authors.affiliation: Department of Home Economics, Aichi Gakusen University. shinpei@he.mirai.ne.jp
authors.forename: Sinpei
authors.initials: S
authors.lastname: Torii
authors.forename: Khoichiro
authors.initials: K
authors.lastname: Hirayama
authors.forename: Kazuo
authors.initials: K
authors.lastname: Akiyama
authors.forename: Zenro
authors.initials: Z
authors.lastname: Ikezawa
authors.forename: Eiichi
authors.initials: E
authors.lastname: Uchio
authors.forename: Yoshitaka
authors.initials: Y
authors.lastname: Okamoto
authors.forename: Hideo
authors.initials: H
authors.lastname: Ogura
authors.forename: Kiyoshi
authors.initials: K
authors.lastname: Takahashi
authors.forename: Sankei
authors.initials: S
authors.lastname: Nishima
mesh_terms: D016902:Air Pollution, Indoor / Q000032:analysis*; D018876:Environmental Illness / Q000175:diagnosis / Q000209:etiology; D005260:Female; D006801:Humans; D008297:Male; D018777:Multiple Chemical Sensitivity / Q000145:classification / Q000209:etiology; D012044:Regression Analysis; D018877:Sick Building Syndrome / Q000145:classification / Q000175:diagnosis / Q000209:etiology