title: [Mortality and hospital discharges in the population of Biancavilla (Sicily) contaminated by natural fibres].
abstract: OBJECTIVE
  The volcanic area of Biancavilla (Sicily Italy) has been included by the Italian national law among the areas of "environmental reclamation" due to the presence of amphibole fluoro-edenitic fibres in the environment. The aim of the study was to evaluate the health of residents in the area, through the analysis of the mortality registry and the hospital discharge records.
  
  
  METHODS
  Age, cause and gender specific indirect standardized mortality ratios SMR (1995-2000) and morbidity ratios SHR (2001-2003) were computed with 95% confidence intervals, using the population of surrounding municipalities as reference.
  
  
  RESULTS
  statistically significant increases in mortality and morbidity were observed, both in men and women, for malignant pleural neoplasms (mortality: men SMR= 700, 6 observed; women SMR= 840, 3 observed; hospital admissions: women SHR= 1210, 5 observed), cardiovascular diseases (mortality: men SMR= 115, 267 observed, women SMR= 115, 278 observed; hospital admissions: men SHR= 109, 631 observed; women SHR= 114, 528 observed) and respiratory diseases (mortality: men SMR= 164, 68 observed; women: SMR= 215, 44 observed; hospital admissions: men SHR= 139, 558 observed, women SHR= 125, 374 observed).
  
  
  CONCLUSIONS
  the excesses observed in this study are consistent with previous findings and suggest the need for further investigations aimed at improving the knowledge of the mineralogical aspects of the fibres, the assessment of human exposure and at estimating the prevalence of pleural plaques and lung fibrosis.
authors.affiliation: Dipartimento osservatorio epidemiologico, Assessorato sanità, Regione Siciliana. achille.cernigliaro@doesicilia.it
authors.forename: Achille
authors.initials: A
authors.lastname: Cernigliaro
authors.forename: Valeria
authors.initials: V
authors.lastname: Fano
authors.forename: Sebastiano Pollina
authors.initials: SP
authors.lastname: Addario
authors.forename: Sebastiana
authors.initials: S
authors.lastname: Caruso
authors.forename: Placido
authors.initials: P
authors.lastname: Pennisi
authors.forename: Francesco
authors.initials: F
authors.lastname: Forastiere
authors.forename: Carlo A
authors.initials: CA
authors.lastname: Perucci
authors.forename: Pietro
authors.initials: P
authors.lastname: Comba
authors.forename: Salvatore
authors.initials: S
authors.lastname: Scondotto
mesh_terms: D017636:Asbestos, Amphibole / Q000009:adverse effects*; D002318:Cardiovascular Diseases / Q000401:mortality; D004781:Environmental Exposure; D005260:Female; D055593:Geological Phenomena; D005844:Geology; D006760:Hospitalization / Q000706:statistics & numerical data; D006801:Humans; D008171:Lung Diseases / Q000401:mortality; D008297:Male; D008499:Medical Records; D008654:Mesothelioma / Q000453:epidemiology / Q000209:etiology* / Q000401:mortality*; D019016:Mineral Fibers / Q000009:adverse effects; D010997:Pleural Neoplasms / Q000453:epidemiology / Q000209:etiology* / Q000401:mortality*; D029424:Pulmonary Disease, Chronic Obstructive / Q000401:mortality; D012802:Sicily / Q000453:epidemiology; D016019:Survival Analysis
chemical_list: D017636:Asbestos, Amphibole; D019016:Mineral Fibers