First report of evaluation of K-M media: a new corneal preservation medium.
OBJECTIVE
To analyze the outcome of keratoplasty performed using Kalevar-Majumdar (K-M) media, a new synthetic viscous medium for preservation of the cornea.


METHODS
The K-M media-preserved donor eye balls were kept in a bottle in a refrigerator at 4 degrees C till the corneas were used. Forty-eight consecutive keratoplasty cases of pseudophakic bullous keratopathy with vision less than counting fingers at one meter and operated by a single surgeon have been analyzed. Corneal donor button of 7.5 mm was used on the 7.0 mm recipient bed in all cases. Surgery was done with a standard technique. All the cases were examined daily for the first week and at the end of one month for graft clarity, epithelial defect and stromal edema.


RESULTS
The K-M media-preserved corneal grafts remained clear at the end of the first week in 95.8% (46 of 48) cases and at the end of one month in 93.7% (45 of 48) cases. Donor epithelial haze cleared in 24 h in all cases. The stromal edema got cleared in the majority (91.7%, 44 of 48) within 24 h. Epithelial defect was seen in only 10.4% (five cases). There was no primary graft failure.


CONCLUSIONS
K-M medium, a new viscous, synthetic corneal preservation medium, is a safe (no primary donor failure) alternative to conventional liquid corneal preservation media. K-M media-preserved eyes appear to have better preserved corneal epithelium with faster achievement of graft clarity postoperatively.
Desai
Beena M
BM
M and J Institute of Ophthalmology, KM School of PG Medicine, Ahmedabad, India. mahadevdesai@yahoo.com
Khamar
B M
BM
Ghodadra
B K
BK
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003315:Cornea; D003316:Corneal Diseases / Q000150:complications / Q000601:surgery*; D016039:Corneal Transplantation; D005260:Female; D006801:Humans; D066298:In Vitro Techniques; D008297:Male; D008875:Middle Aged; D019188:Organ Preservation Solutions / Q000138:chemical synthesis* / Q000592:standards*; D019591:Pseudophakia / Q000150:complications; D012189:Retrospective Studies; D016896:Treatment Outcome
C521380:K-M media; D019188:Organ Preservation Solutions