[Penile squamous carcinoma in circumcised patients: a report 17 cases].
OBJECTIVE
To discuss the diagnosis and treatment of penile carcinoma in circumcised men.


METHODS
We reviewed 17 cases of penile carcinoma detected 1 month to 16 years after circumcision performed in our hospital from January, 1997 to December, 2004.


RESULTS
Of the total number, 11 cases were diagnosed as penile carcinoma 1 - 12 months and the others 3 - 16 years after the circumcision. Sixteen of them were treated by partial penectomy, anti 1 first by extensive circumcision and later by partial and total penectomy successively after recurrence. Cloquet nodes biopsy showed 16 cases to be pathologically well-differentiated and I case moderately differentiated penile squamous carcinoma. One died of extensive metastasis, but the other 16 remained disease-free survivals.


CONCLUSIONS
Circumcised adult men, especially those over 40 years of age, are likely to develop penile carcinoma. Patients with inflammation, plaque or ulcer in the prepuce should be checked by pathological biopsy and followed up closely. For Stage-I penile squamous carcinoma, partial penectomy is shown to be an effective therapeutic option, and Cloquet's nodes biopsy is necessary for all patients.
Wan
Qun
Q
Department of Urology, First Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310003, China. hz_uro@163.com
Li
Zhong-yi
ZY
Shen
Zhou-jun
ZJ
Zhu
Xuan-wen
XW
Zhang
Zhi-gen
ZG
Cai
Song-liang
SL
D000328:Adult; D002294:Carcinoma, Squamous Cell / Q000209:etiology*; D002944:Circumcision, Male; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D010412:Penile Neoplasms / Q000209:etiology*; D010688:Phimosis / Q000150:complications* / Q000601:surgery; D011184:Postoperative Period; D012189:Retrospective Studies