title: Clozapine-induced angioneurotic edema.
abstract: Many prescribed drugs can cause cutaneous rashes and eruptions, which may present in various forms and severity. Most of these reactions are mild; however, the severe cases can lead to life-threatening complications. The most severe of these reactions may include angioedema, acute generalized exanthematous reactions, Stevens-Johnson syndrome and toxic epidermal necrolysis. We report two cases wherein the patients developed classical angioneurotic edema on clozapine therapy and improved rapidly when clozapine was stopped.
authors.affiliation: Central Institute of Psychiatry, Ranchi 834 006, India. drasoy@gmail.com
authors.forename: Biswaranjan
authors.initials: B
authors.lastname: Mishra
authors.forename: Saddichha
authors.initials: S
authors.lastname: Sahoo
authors.forename: Sukanto
authors.initials: S
authors.lastname: Sarkar
authors.forename: Sayeed
authors.initials: S
authors.lastname: Akhtar
mesh_terms: D000799:Angioedema / Q000139:chemically induced* / Q000175:diagnosis; D014150:Antipsychotic Agents / Q000009:adverse effects*; D003024:Clozapine / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012559:Schizophrenia / Q000188:drug therapy*
chemical_list: D014150:Antipsychotic Agents; D003024:Clozapine