title: Dramatic tumour response to pemetrexed single-agent in an elderly patient with malignant peritoneal mesothelioma: a case report.
abstract: BACKGROUND
  To date, there is no standard treatment for unresectable malignant peritoneal mesothelioma; either best supportive care or systemic chemotherapy with palliative intent are accepted options.
  
  
  METHODS
  Here, we report the case of a 79-year old patient with malignant peritoneal mesothelioma who was treated with pemetrexed single-agent and obtained an impressive long-lasting response.
  
  
  CONCLUSIONS
  Single-agent pemetrexed is a treatment option for malignant peritoneal mesothelioma in selected elderly patients or in patients with unpaired performance status.
authors.affiliation: Dept. of Medical Oncology, University Hospital, P.le S. M. Misericordia, 33100 Udine, Italy. fasola.gianpiero@aoud.sanita.fvg.it
authors.forename: Gianpiero
authors.initials: G
authors.lastname: Fasola
authors.forename: Fabio
authors.initials: F
authors.lastname: Puglisi
authors.forename: Alessandro
authors.initials: A
authors.lastname: Follador
authors.forename: Marianna
authors.initials: M
authors.lastname: Aita
authors.forename: Silvia
authors.initials: S
authors.lastname: Di Terlizzi
authors.forename: Ornella
authors.initials: O
authors.lastname: Belvedere
mesh_terms: D000368:Aged; D000964:Antimetabolites, Antineoplastic / Q000627:therapeutic use*; D005971:Glutamates / Q000627:therapeutic use*; D006147:Guanine / Q000031:analogs & derivatives* / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008654:Mesothelioma / Q000188:drug therapy*; D000068437:Pemetrexed; D010534:Peritoneal Neoplasms / Q000188:drug therapy*
chemical_list: D000964:Antimetabolites, Antineoplastic; D005971:Glutamates; D000068437:Pemetrexed; D006147:Guanine