title: Retrograde transfer of testosterone to the porcine ovary in follicular and luteal phase of the estrous cycle in vivo.
abstract: This study was designed to determine the efficiency and rate of testosterone (T) retrograde transfer during the follicular and luteal phase of the estrous cycle in gilts (n=27). The efficiency and the rate of the retrograde transfer of T from the ovarian effluent into blood supplying the ovary were determined for the first time under in vivo conditions. Ovarian arterial blood concentration of T was higher than that in systemic blood during both, the follicular phase (p<0.01) and luteal phase (p<0.0001). The efficiency of the retrograde transfer of T into ovarian arterial blood was not dependent on concentration of testosterone in the ovarian venous blood. However, the efficiency and the rate of the retrograde transfer of T differed between phases of the estrous cycle. The presented results suggest that local retrograde transfer enriched the porcine ovary with an additional amount of T which may affect the ovarian secretory function.
authors.affiliation: Division of Reproductive Endocrinology and Pathophysiology, Institute of Animal Reproduction and Food Research, Polish Academy of Sciences, 10-747 Olsztyn, ul. Tuwima 10, Poland. bwasow@pan.olsztyn.pl
authors.forename: Barbara
authors.initials: B
authors.lastname: Wasowska
authors.forename: Stanisława
authors.initials: S
authors.lastname: Stefańczyk-Krzymowska
mesh_terms: D000818:Animals; D030762:Estrous Cycle / Q000097:blood*; D005260:Female; D007601:Jugular Veins; D010053:Ovary / Q000098:blood supply* / Q000378:metabolism*; D013552:Swine; D013739:Testosterone / Q000097:blood*; D014599:Uterus / Q000098:blood supply
chemical_list: D013739:Testosterone