Scytalidium keratitis: case report in a human eye.
OBJECTIVE
To describe the presentation and treatment of a case of an atypical reticular corneal infiltrate with surrounding immune-like ring in a young woman caused by Scytalidium fungal species.


METHODS
Interventional case report describing the clinical appearance, course, and treatment of Scytalidium keratitis.


RESULTS
A 21-year-old female equestrian with a history of soft contact lens wear was noted to have persistent keratitis and photophobia of the right eye after an injury with a volleyball. Although initially culture negative and responsive to topical steroids, the keratitis persisted, and repeat corneal scrapings and cultures revealed Scytalidium species. Treatment with topical amphotericin B 0.15% and oral fluconazole 200 mg twice daily eradicated the infection, and the patient had a final best-corrected visual acuity of 20/20.


CONCLUSIONS
Scytalidium species fungal organisms can cause an indolent keratitis. Intensive oral and topical antifungal therapy was successful in eradicating the infection.
Farjo
Qais A
QA
Vision Associates, Toledo, OH 43615, USA. qaisf@umich.edu
Farjo
Rand S
RS
Farjo
Ayad A
AA
D000284:Administration, Oral; D000287:Administration, Topical; D000328:Adult; D000666:Amphotericin B / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use; D001203:Ascomycota / Q000302:isolation & purification*; D003320:Corneal Ulcer / Q000188:drug therapy / Q000382:microbiology*; D004359:Drug Therapy, Combination; D015821:Eye Infections, Fungal / Q000188:drug therapy / Q000382:microbiology*; D005260:Female; D015725:Fluconazole / Q000627:therapeutic use; D006801:Humans; D009181:Mycoses / Q000188:drug therapy / Q000382:microbiology*
D000935:Antifungal Agents; D000666:Amphotericin B; D015725:Fluconazole