title: Nursing considerations for clofarabine in the treatment of acute lymphoblastic leukemia in children.
abstract: Each year, almost 3500 children are diagnosed with leukemia, representing approximately 30% of pediatric cancer cases. Acute lymphoblastic leukemia is the most common form of pediatric leukemia, accounting for approximately 80% of cases. A significant number of children fail to respond to existing chemotherapies or are unable to maintain remission. Their prognosis is poor, with little hope for long-term survival.
authors.affiliation: University of Texas M.D. Anderson Cancer Center, Houston, USA. lrmcdona@mdanderson.org
authors.forename: Lisa R
authors.initials: LR
authors.lastname: McDonald
authors.forename: Colleen H
authors.initials: CH
authors.lastname: McCarthy
mesh_terms: D000227:Adenine Nucleotides / Q000009:adverse effects / Q000627:therapeutic use*; D001087:Arabinonucleosides / Q000009:adverse effects / Q000627:therapeutic use*; D002648:Child; D017322:Clinical Trials, Phase II as Topic; D000077866:Clofarabine; D004334:Drug Administration Schedule; D016903:Drug Monitoring; D006801:Humans; D024802:Nurse's Role; D009859:Oncology Nursing / Q000458:organization & administration*; D017410:Practice Guidelines as Topic; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000188:drug therapy* / Q000453:epidemiology / Q000451:nursing*; D011379:Prognosis; D012008:Recurrence; D012074:Remission Induction; D015996:Survival Rate; D016896:Treatment Outcome
chemical_list: D000227:Adenine Nucleotides; D001087:Arabinonucleosides; D000077866:Clofarabine