[Does transrectal MRI before radical prostatectomy modify the operative technique to decrease the positive margin rate?].
OBJECTIVE
To determine the value of magnetic resonance imaging (MRI) in the surgical management of prostate cancer patients.


METHODS
159 patients with prostate cancer underwent transrectal MRI before retropubic radical prostatectomy (RP). Patients operated despite a suspicion of extraprostatic extension on MRI had a modified non-nerve-sparing surgical technique. Postoperative histological findings were compared to MRI data.


RESULTS
34/159 patients (21.4%) had suspected extraprostatic extension in MRI. The pT3 rate on the RP specimen was significantly higher for patients with abnormal MRI than for patients with normal MRI (61% versus 39%, p = 0.02). Among pT3 patients, the positive surgical margin rate was significantly lower in the group with abnormal MRI than in the group with normal MRI (24% versus 51%, p = 0.035).


CONCLUSIONS
Among patients with stage pT3 on the RP specimen, those in whom extraprostatic extension was suspected on MRI were treated by a modified surgical technique resulting in a lower positive surgical margin rate.
Descazeaud
Aurélien
A
Service d'Urologie, Hôpital Cochin, Paris, France. aureliendescazeaud@hotmail.com
Peyromaure
Michael
M
Vieillefond
Annick
A
Bernard
Debré
D
Zerbib
Marc
M
D000368:Aged; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D011300:Preoperative Care; D011468:Prostatectomy / Q000379:methods*; D011471:Prostatic Neoplasms / Q000473:pathology* / Q000601:surgery*