title: Pathophysiology of cerebral venous thrombosis--an overview.
abstract: Cerebral venous sinus thrombosis is a disorder with a unique pathophysiology which needs to be described. A Medline search of all articles detailing pathophysiology of CVST was done, using keywords: cerebral venous thrombosis and pathophysiology. In addition, major texts were reviewed for additional references. The pathophysiology of CVST depends on two interconnected events, local signs due to venous infarct, e.g., hemiparesis and global signs due to raised ICP from an obstructed venous system--papilloedema and isolated intracranial hypertension being one of them. Pathophysiology of CVST is diverse and makes it easier to understand the diversity of clinical presentations.
authors.affiliation: Department of Neurology, The Aga Khan University, Karachi.
authors.forename: Ahmed
authors.initials: A
authors.lastname: Itrat
authors.forename: Sana
authors.initials: S
authors.lastname: Shoukat
authors.forename: Ayeesha K
authors.initials: AK
authors.lastname: Kamal
mesh_terms: D002550:Cerebral Veins / Q000473:pathology*; D006801:Humans; D020767:Intracranial Thrombosis / Q000209:etiology / Q000503:physiopathology*; D011379:Prognosis; D012307:Risk Factors; D012851:Sinus Thrombosis, Intracranial / Q000209:etiology / Q000503:physiopathology*; D020246:Venous Thrombosis / Q000209:etiology / Q000503:physiopathology*