title: Update on gingival overgrowth by cyclosporine A in renal transplants.
abstract: Severe gingival overgrowth is one of the most frequent side effects in renal transplant patients associated with assumption of cyclosporine A. Several associations with age, sex, dosage, duration of therapy or interval since transplantation have been hypothesized. The introduction of alternative immunosuppressant drugs have been suggested to permit better long-term transplant outcomes and a decrease in incidence of gingival overgrowth. The aim of the present paper is to summarize current knowledge regarding aetiology, pathogenesis and management of gingival overgrowth induced by Cyclosporine A.
authors.affiliation: Department of Surgical Sciences, University of Foggia, Foggia, Italy.
authors.forename: Domenico
authors.initials: D
authors.lastname: Ciavarella
authors.forename: Rosario
authors.initials: R
authors.lastname: Guiglia
authors.forename: Giuseppina
authors.initials: G
authors.lastname: Campisi
authors.forename: Michele
authors.initials: M
authors.lastname: Di Cosola
authors.forename: Chiara
authors.initials: C
authors.lastname: Di Liberto
authors.forename: Antonio
authors.initials: A
authors.lastname: Sabatucci
authors.forename: Nayra
authors.initials: N
authors.lastname: Escudero
authors.forename: Antonio
authors.initials: A
authors.lastname: Bascones
authors.forename: Lorenzo
authors.initials: L
authors.lastname: Lo Muzio
mesh_terms: D016572:Cyclosporine / Q000009:adverse effects*; D019214:Gingival Overgrowth / Q000139:chemically induced*; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects*; D016030:Kidney Transplantation; D011183:Postoperative Complications / Q000139:chemically induced*
chemical_list: D007166:Immunosuppressive Agents; D016572:Cyclosporine