title: Clear-cell endocervical adenocarcinoma in a 19-year-old woman.
abstract: The incidence of adenocarcinoma of the cervix is increasing within the US, but this diagnostic category is not typically associated with teenaged patients. A report on a case of a 19-year-old woman, with no history of diethylbestrol exposure in uteri, diagnosed with clear-cell endocervical adenocarcinoma is made. Malignant glandular cells were detected on both conventional and Thin Prep gynecologic tests with histologic confirmation. Human papilloma virus (HPV) high-risk type results were negative in this particular case. The patient's unremarkable medical and sexual history prompted us to review the diagnostic criteria and pathogenesis of the disease.
authors.affiliation: Cytopathology Section, Department of Pathology and Laboratory Medicine, University of Wisconsin Medical School, 600 Highland Avenue, Madison, WI 53792, USA. jj.stewart@hosp.wisc.edu
authors.forename: Jimmie
authors.initials: J
authors.lastname: Stewart
authors.forename: Kristen
authors.initials: K
authors.lastname: Bevans-Wilkins
authors.forename: Changhong
authors.initials: C
authors.lastname: Ye
authors.forename: Daniel F I
authors.initials: DF
authors.lastname: Kurtycz
mesh_terms: D018262:Adenocarcinoma, Clear Cell / Q000175:diagnosis / Q000209:etiology / Q000473:pathology*; D000328:Adult; D003581:Cytodiagnosis / Q000379:methods; D005260:Female; D006801:Humans; D012307:Risk Factors; D002583:Uterine Cervical Neoplasms / Q000175:diagnosis / Q000209:etiology / Q000473:pathology*; D014626:Vaginal Smears