The cytotoxicity of saponins correlates with their cellular internalization.
Wang
Yibing
Y
State Key Laboratory of Bioorganic and Natural Products Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 354 Fenglin Road, Shanghai 200032, China.
Zhang
Yichun
Y
Yu
Biao
B
D000818:Animals; D045744:Cell Line, Tumor; D002462:Cell Membrane / Q000378:metabolism*; D004705:Endocytosis / Q000187:drug effects*; D005456:Fluorescent Dyes / Q000032:analysis / Q000737:chemistry; D006801:Humans; D020128:Inhibitory Concentration 50; D008247:Lysosomes / Q000378:metabolism; D015394:Molecular Structure; D009369:Neoplasms / Q000188:drug therapy; D012503:Saponins / Q000494:pharmacology* / Q000627:therapeutic use / Q000633:toxicity; D013150:Spirostans / Q000737:chemistry*; D013329:Structure-Activity Relationship
D005456:Fluorescent Dyes; D012503:Saponins; D013150:Spirostans