New functions for Y family polymerases.
The Y family of DNA polymerases plays crucial roles in carrying out translesion synthesis past damaged bases in DNA. Several recent papers suggest that they might have other roles as well in gene conversion, in nucleotide excision repair (NER), and in DNA replication under stressed conditions.
Lehmann
Alan R
AR
Genome Damage and Stability Centre, University of Sussex, Falmer, Brighton BN1 9RQ, United Kingdom. r.lehmann@sussex.ac.uk
D000818:Animals; D002453:Cell Cycle; D004260:DNA Repair; D004261:DNA Replication / Q000502:physiology*; D004259:DNA-Directed DNA Polymerase / Q000502:physiology*; D006801:Humans; D009687:Nuclear Proteins; D009713:Nucleotidyltransferases / Q000502:physiology; D011995:Recombination, Genetic; D000099270:Y-Family DNA Polymerases
D004259:DNA-Directed DNA Polymerase; D009687:Nuclear Proteins; D009713:Nucleotidyltransferases; C429004:REV1 protein, human; D000099270:Y-Family DNA Polymerases