Structure and binding properties of water-soluble cavitands and capsules.
Synthetic receptors are modern tools for investigations into the forces involved in recognition. A widely exploited class of receptors are the resorcin[4]arene-based cavitands and capsules. This critical review (71 references) describes the evolution of water-soluble versions of these structures, along with insights the resulting host-ndash complexes have provided with regard to complexation driving forces in water. An emphasis has been placed on the influence of host structure on guest affinity and dynamics.
Biros
Shannon M
SM
The Skaggs Institute for Chemical Biology, Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, MB26, La Jolla, CA 92037, USA.
Rebek
Julius
J
D004988:Ethers, Cyclic / Q000737:chemistry*; D015394:Molecular Structure; D012995:Solubility; D014867:Water / Q000737:chemistry*
D004988:Ethers, Cyclic; D014867:Water