Adenosine deaminase in ischemia reperfusion injury in patients with myocardial infarction.
A comparative study on the levels of erythrocyte adenosine deaminase and lipid peroxidation has been undertaken in patients with myocardial infarction before and after thrombolysis along with matched healthy individuals. Our findings show that adenosine deaminase activity is highly elevated in post-reperfused patients when compared to pre- thrombolysed and healthy persons. Malondialdehyde(MDA) levels are also significantly increased in post-thrombolysed patients. The study reveals an important role of adenosine deaminase in reperfusion injury in patients with myocardial infarction.
Kaul
Aiki
A
Department of Biochemistry, Lucknow University, Lucknow 226 007, India.
Chandra
M
M
Misra
M K
MK
D000243:Adenosine Deaminase / Q000378:metabolism*; D000328:Adult; D000368:Aged; D004912:Erythrocytes / Q000378:metabolism; D006801:Humans; D008297:Male; D008315:Malondialdehyde / Q000378:metabolism; D008875:Middle Aged; D009203:Myocardial Infarction / Q000150:complications / Q000201:enzymology* / Q000473:pathology; D015428:Myocardial Reperfusion Injury / Q000201:enzymology* / Q000209:etiology / Q000473:pathology
D008315:Malondialdehyde; D000243:Adenosine Deaminase