title: Part I: spinal-cord neoplasms-intradural neoplasms.
abstract: Intradural spinal-cord tumours are an uncommon but important consideration in the differential diagnosis of patients with back pain, radicular pain, sensorimotor deficits, or sphincter dysfunction. Intradural spinal tumours can be divided into intramedullary and extramedullary spinal-cord tumours on the basis of their anatomical relation to the spinal parenchyma. The heterogeneous cell composition of the intradural compartment allows the formation of neoplasms, arising from glial cells, neurons, and cells of spinal vasculature. Additionally, developmental tumours, metastases, and intradural extension of extradural tumours are represented. In this Review, we discuss the published work on intradural spinal-cord tumours in terms of epidemiological, radiographic, and histological characteristics. Surgical and adjuvant treatment strategies are also reviewed.
authors.affiliation: Department of Neurology, University of Virginia Health System, Charlottesville, VA 22908, USA.
authors.forename: David E
authors.initials: DE
authors.lastname: Traul
authors.forename: Mark E
authors.initials: ME
authors.lastname: Shaffrey
authors.forename: David
authors.initials: D
authors.lastname: Schiff
mesh_terms: D006801:Humans; D013120:Spinal Cord Neoplasms / Q000145:classification / Q000473:pathology*