title: [Results of vacuum sealing therapy in joint infections].
abstract: OBJECTIVE
  At present the vacuum sealing technique is acknowledged as a therapy for acute and chronic wounds. An acceleration of the healing process, due to the vacuum suction with occlusive wound dressing, leads to the shortening of a cost-effective medical treatment. This can be applied to wound treatment and infections of soft tissues, but even today there is only sparse information in this context about joint infections.
  
  
  METHODS
  The results of therapy with the vacuum sealing technique in 68 patients with infections of the joints of an extremity or the trunk were analysed in a retrospective study without a control group. The importance of several patient-related factors for the medical treatment have been analysed.
  
  
  RESULTS
  An adequate treatment of joint infections can be achieved even in the presence of endoprostheses or osteosynthetic material. The following factors have been found to be of significance for a prolonged medical treatment: diabetes mellitus (p=0.0052), obesity (BMI>25) (p=0.0458) and a preceding trauma (p=0.0457).
  
  
  CONCLUSIONS
  The results confirm the value of the vacuum sealing technique following surgical debridement in combination with resistance tested antibiotic treatment, as a sufficient therapy for joint infections, even in patients with an endoprosthesis. This procedure leads to a safe treatment of the joint infection, combined with a good function of the treated joint, good patient comfort and a short duration of the therapy.
authors.affiliation: Orthopädische Universitätsklinik, Universitätsklinikum Tübingen, Germany. martin.luedemann@med.uni-tuebingen.de
authors.forename: M
authors.initials: M
authors.lastname: Lüdemann
authors.forename: S
authors.initials: S
authors.lastname: Haid
authors.forename: N
authors.initials: N
authors.lastname: Wülker
authors.forename: M
authors.initials: M
authors.lastname: Rudert
mesh_terms: D000038:Abscess / Q000601:surgery; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001170:Arthritis, Infectious / Q000601:surgery*; D001424:Bacterial Infections / Q000601:surgery*; D002648:Child; D003646:Debridement; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009779:Occlusive Dressings; D011142:Polyvinyl Alcohol; D011182:Postoperative Care; D012086:Reoperation; D015503:Surgical Sponges; D013530:Surgical Wound Infection / Q000601:surgery; D014619:Vacuum Curettage; D014945:Wound Healing / Q000502:physiology
chemical_list: D011142:Polyvinyl Alcohol