Hepatocyte apoptosis in hepatitis C/HIV co-infection.
Hepatocytes exposed in vitro to hepatitis C virus (HCV) and human immunodeficiency virus (HIV) envelope proteins and undergo apoptosis as a result of cell surface binding of the proteins. The studies indicate that HCV/HIV envelope proteins induce hepatocyte apoptosis by activating a novel downstream STAT1 signaling pathway.
Winslow
Dean L
DL
Division of AIDS Medicine, Santa Clara Valley Medical Center, California, USA.