title: [The clinicomethodological aspects of the etiology of coronary artery disease].
abstract: Having analyzed more than 150 original papers dedicated to the study of cardial pathology risk factors from clinical (specific) and methodological (philosophic) points of view, the authors put forward a hypothesis of the etiology of diseases (by the example of coronary artery disease) as a "critical mass" of these risk factors. Reasoning from it, the authors suggest the ways of using this statement by large quantitative evaluation of clinical data, and application of mathematic modeling to the diagnostics and prognostics of cardial pathology in each particular case.
authors.forename: L A
authors.initials: LA
authors.lastname: Leshchinskiĭ
authors.forename: A S
authors.initials: AS
authors.lastname: Dimov
authors.forename: N I
authors.initials: NI
authors.lastname: Maksimov
mesh_terms: D000328:Adult; D000367:Age Factors; D005260:Female; D006801:Humans; D006946:Hyperinsulinism / Q000150:complications; D006949:Hyperlipidemias / Q000150:complications; D008297:Male; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000209:etiology* / Q000401:mortality / Q000503:physiopathology*; D009765:Obesity / Q000453:epidemiology; D012307:Risk Factors