[Analysis of failed management of endometrial carcinoma].
The research included 155 patients with relapsing tumors of the corpus uteri and metastases which developed after surgical, combination and multimodality treatment. Metastases were found to occur most within the first 12 months of follow-up due to faulty staging and inadequate choice of therapy 51%. Tumor frequency range was as follows: single--60.6%, multiple tumor--22.6% and lymphogenous metastases--16.8%. Vaginal stump involvement prevailed in cases of single tumors; para-aortal node involvement--lymph nodes. Recurrences were as frequent in the vaginal stump cupola (9.7%) as in the remaining parametrium (9.7%). It is important that endometrial carcinoma staging take into account the histological pattern and site of tumor in the uterine cavity in order to examine organs in which metastases are most likely to occur. Preoperative high-dosage brachytherapy should be conducted to minimize the likelihood of relapse.
Zalutskiĭ
I V
IV
Litvinova
T M
TM
D000328:Adult; D000368:Aged; D002277:Carcinoma / Q000556:secondary* / Q000628:therapy*; D003131:Combined Modality Therapy; D016889:Endometrial Neoplasms / Q000473:pathology* / Q000628:therapy*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008207:Lymphatic Metastasis; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D009367:Neoplasm Staging; D016896:Treatment Outcome