title: [Effect of monohydric aliphatic alcohols on children's health].
abstract: To form the evidence base of the "environmental determination" of disease is a topical line in human ecology and environmental hygiene. The widespread use of monohydric aliphatic alcohols in industry has determined the necessity of making an in-depth study of their toxic effects on man, by taking into account their actual concentrations forming in the blood. The results of the studies have led to the conclusion that the real risk of toxic exposure of an organism to monohydric alcohols forms when the blood concentrations of butyl alcohols, propyl alcohols, and methyl alcohol are over 0.03, 1.0-1.5, and 0.5 microg/kg/cm3, respectively. Toxic exposure involves immunosuppressive, oxidative, hematoxic, and sensitizing effects and impaired hepatic etherifying function. With the higher toxicity of the compounds, the damaging action of monohydric alcohols on the organism increases and the spectrum of abnormal clinical and laboratory parameters expands.
authors.forename: N V
authors.initials: NV
authors.lastname: Zaĭtseva
authors.forename: M A
authors.initials: MA
authors.lastname: Zemlianova
authors.forename: P Z
authors.initials: PZ
authors.lastname: Shur
authors.forename: D A
authors.initials: DA
authors.lastname: Kir'ianov
mesh_terms: D002648:Child; D004781:Environmental Exposure / Q000009:adverse effects* / Q000032:analysis; D018876:Environmental Illness / Q000097:blood / Q000139:chemically induced* / Q000276:immunology; D005233:Fatty Alcohols / Q000009:adverse effects* / Q000493:pharmacokinetics; D006801:Humans; D007111:Immunity, Cellular / Q000187:drug effects; D000432:Methanol / Q000009:adverse effects* / Q000493:pharmacokinetics; D012189:Retrospective Studies
chemical_list: D005233:Fatty Alcohols; D000432:Methanol