In vitro activities of amphotericin B, caspofungin, itraconazole, posaconazole, and voriconazole against 45 clinical isolates of zygomycetes: comparison of CLSI M38-A, Sensititre YeastOne, and the Etest.
We evaluated the activities of amphotericin B, itraconazole, voriconazole, caspofungin, and posaconazole against zygomycetes by CLSI M38-A, Etest and Sensititre. The most active drug was posaconazole, followed by amphotericin B and itraconazole. The correlation of the Etest and Sensititre with CLSI M38-A was moderate for posaconazole but poor for the others.
Torres-Narbona
Marta
M
Servicio de Microbiología Clínica, Hospital Universitario Gregorio Marañón, Dr. Esquerdo 46, 28007 Madrid, Spain.
Guinea
Jesús
J
Martínez-Alarcón
José
J
Peláez
Teresa
T
Bouza
Emilio
E
D000935:Antifungal Agents / Q000494:pharmacology*; D005658:Fungi / Q000187:drug effects*; D006801:Humans; D008826:Microbial Sensitivity Tests / Q000295:instrumentation*; D011786:Quality Control; D020096:Zygomycosis / Q000382:microbiology*
D000935:Antifungal Agents