title: Synthesis of fluorescent molecular probes specific for the receptor of blepharismone, a mating-inducing pheromone of the ciliate Blepharisma japonicum.
abstract: Blepharismone (gamone 2) is a mating-inducing pheromone of the ciliate Blepharisma japonicum. N-Pyrenylbutyryl-blepharismone and N-biphenylacetyl-blepharismone, which are fluorescent derivatives of blepharismone, were synthesized as molecular probes for the gamone 2 receptor. Further, we proved that they have inhibitory activities against the blepharismone-induced monotypic pairing of B. japonicum.
authors.affiliation: Department of Material Science, Graduate School of Science, Osaka City University, Osaka 558-8585, Japan.
authors.forename: Yoshiyuki
authors.initials: Y
authors.lastname: Uruma
authors.forename: Mayumi
authors.initials: M
authors.lastname: Sugiura
authors.forename: Terue
authors.initials: T
authors.lastname: Harumoto
authors.forename: Yoshinosuke
authors.initials: Y
authors.lastname: Usuki
authors.forename: Hideo
authors.initials: H
authors.lastname: Iio
mesh_terms: D000627:Aminophenols; D000818:Animals; D005456:Fluorescent Dyes / Q000138:chemical synthesis*; D062385:Hydroxybenzoates / Q000037:antagonists & inhibitors* / Q000138:chemical synthesis; D007773:Lactates; D015800:Protozoan Proteins / Q000037:antagonists & inhibitors; D043563:Receptors, Pheromone / Q000032:analysis / Q000037:antagonists & inhibitors; D012724:Sex Attractants / Q000037:antagonists & inhibitors*
chemical_list: D000627:Aminophenols; D005456:Fluorescent Dyes; D062385:Hydroxybenzoates; D007773:Lactates; D015800:Protozoan Proteins; D043563:Receptors, Pheromone; D012724:Sex Attractants; C012329:blepharismone