[Hemodynamic instability and long-term lithium therapy].
Lithium is known to be responsible for many adverse events on the cardiovascular system. Among these events, it was experimentally noted that lithium could block the action of catecholamines on myocardium. The authors report the case of a patient under lithium therapy developing a myocardial infarction secondarily complicated of a severe cardiac failure. The inotropic support essential to balance hemodynamic could be raised only after lithium's stop. This example could be a clinical translation of the experimental effect previously observed.
Rolland
B
B
Service de psychiatrie adulte, hôpital Fontan, centre hospitalier universitaire de Lille, rue André-Veraeghe, 59000 Lille, France. benjamin.rolland3@wanadoo.fr
Pretorian
E M
EM
Grozieux de Laguerenne
N
N
Jaboureck
O
O
Cottencin
O
O
D000368:Aged; D000928:Antidepressive Agents / Q000009:adverse effects* / Q000627:therapeutic use; D001714:Bipolar Disorder / Q000188:drug therapy; D006321:Heart / Q000187:drug effects*; D006333:Heart Failure / Q000139:chemically induced; D006801:Humans; D016651:Lithium Carbonate / Q000009:adverse effects* / Q000627:therapeutic use; D008297:Male; D009203:Myocardial Infarction / Q000139:chemically induced* / Q000628:therapy; D016896:Treatment Outcome
D000928:Antidepressive Agents; D016651:Lithium Carbonate