title: Sudden sensorineural hearing loss and antiphospholipid syndrome.
abstract: The antiphospholipid syndrome is the association between the presence of antiphospholipid antibodies, thrombosis and/or pregnancy morbidity and mortality. This report presents two cases of antiphospholipid antibodies and sensorineural hearing loss and discusses the probable causative link. We recommend that patients presenting with sudden sensorineural hearing loss are investigated for evidence of antiphospholipid antibodies. Life long anticoagulation is necessary to prevent life threatening thrombotic or thromboembolic events.
authors.affiliation: Department of Otolaryngology, Guys and St. Thomas' NHS Trust, Lambeth Palace Road, London SE1 7EH.
authors.forename: Natasha M
authors.initials: NM
authors.lastname: Wiles
authors.forename: Beverley J
authors.initials: BJ
authors.lastname: Hunt
authors.forename: Vincent
authors.initials: V
authors.lastname: Callanan
authors.forename: Elfy B
authors.initials: EB
authors.lastname: Chevretton
mesh_terms: D000925:Anticoagulants / Q000627:therapeutic use; D016736:Antiphospholipid Syndrome / Q000097:blood / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D004244:Dizziness / Q000209:etiology; D006319:Hearing Loss, Sensorineural / Q000209:etiology*; D003639:Hearing Loss, Sudden / Q000209:etiology*; D046088:Hearing Loss, Unilateral / Q000209:etiology*; D006801:Humans; D016682:Lupus Coagulation Inhibitor / Q000032:analysis; D008297:Male; D008875:Middle Aged; D019851:Thrombophilia / Q000188:drug therapy / Q000209:etiology; D013927:Thrombosis / Q000209:etiology*; D014717:Vertigo / Q000209:etiology; D014859:Warfarin / Q000627:therapeutic use
chemical_list: D000925:Anticoagulants; D016682:Lupus Coagulation Inhibitor; D014859:Warfarin