Post-irradiation carcinosarcoma of uterus--a case report.
The carcinosarcoma (malignant mixed mullerian tumour) of uterus is an aggressive neoplasm composing of malignant glands in the malignant stroma showing biphasic appearance. A 55 year old woman presented with discharge per vaginum of one month duration. Earlier she was given radiotherapy for squamous cell carcinoma of vulva, six years back. Abdominal examination was insignificant. USG suggested presence of post-radiation effect with uterine mass. Panhysterectomy was done and on histopathology, the diagnosis of carcinosarcoma (heterologous variant) was made. The case is being reported and discussed.
Sharma
A Barindra
AB
Department of Pathology, Regional Institute of Medical Sciences, Imphal 795 004, Manipur. abarindra@yahoo.co.in
Pukhrambam
Gayatri
G
Laishram
Sharmila
S
D002294:Carcinoma, Squamous Cell / Q000532:radiotherapy; D002296:Carcinosarcoma / Q000175:diagnosis / Q000209:etiology* / Q000473:pathology; D005260:Female; D006801:Humans; D008875:Middle Aged; D018200:Mixed Tumor, Mullerian / Q000175:diagnosis / Q000209:etiology* / Q000473:pathology; D009381:Neoplasms, Radiation-Induced / Q000175:diagnosis / Q000209:etiology*; D016609:Neoplasms, Second Primary / Q000175:diagnosis / Q000209:etiology*; D014594:Uterine Neoplasms / Q000175:diagnosis / Q000209:etiology* / Q000473:pathology; D014846:Vulvar Neoplasms / Q000532:radiotherapy