title: Ulcerative keratitis associated with contact lens wear.
abstract: To review the microbiological profile of ulcerative keratitis associated with contact lens (CL)-wear, 35 patients with culture-proven CL-associated microbial keratitis were studied between September 1999 and September 2002. Corneal scrapes and CL-care products were collected and were subjected to microbiological evaluation. Gram-negative bacilli alone were recovered from the corneal scrapes of all 35 (100%) patients, all 70 (100%) CL storage case wells and also from CL-care solution of six (17.14%) of the 35 patients. There was a significantly higher number of Pseudomonas aeruginosa (71.43%) isolated from eyes with CL-related keratitis than other bacterial isolates (28.57%) (P<0.001). Microbial contamination of CL storage cases was a great risk for gram-negative bacterial infection among soft CL-wearers.
authors.affiliation: Microbiology Research Centre, Tirunelveli, Tamil Nadu-627 001, India. jayahar@tvl.aravind.org
authors.forename: M Jayahar
authors.initials: MJ
authors.lastname: Bharathi
authors.forename: R
authors.initials: R
authors.lastname: Ramakrishnan
authors.forename: R
authors.initials: R
authors.lastname: Meenakshi
authors.forename: C Shiv
authors.initials: CS
authors.lastname: Kumar
authors.forename: S
authors.initials: S
authors.lastname: Padmavathy
authors.forename: S
authors.initials: S
authors.lastname: Mittal
mesh_terms: D000293:Adolescent; D000328:Adult; D018639:Contact Lens Solutions; D003261:Contact Lenses / Q000009:adverse effects*; D003315:Cornea / Q000382:microbiology; D003320:Corneal Ulcer / Q000453:epidemiology / Q000209:etiology* / Q000382:microbiology; D004340:Drug Contamination; D004754:Enterobacter / Q000302:isolation & purification; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D011550:Pseudomonas aeruginosa / Q000302:isolation & purification
chemical_list: D018639:Contact Lens Solutions