title: Effect of war and postwar genotoxins on micronuclei frequency in Sarajevo study group.
abstract: During the 1992-1995 siege, as well as after the war activities, citizens of Sarajevo were most probably exposed to various potential genotoxic agents. The effects of those potential genotoxins were evaluated by micronucleus-cytokinesis blocked assay. The study included 30 individuals who resided in the area of Sarajevo during the war and the postwar period. Point bi-serial coefficient analysis did not reveal any relationship between the frequencies of binuclear cells with micronuclei as well as total number of micronuclei and smoking habits or gender. Simple linear regression revealed statistically significant positive correlation between the age and micronuclei formation. Due to the war related environmental contamination more extensive study is recommended.
authors.affiliation: Faculty of Medicine, University of Sarajevo, Cekalusa 90, 71000 Sarajevo, Bosnia and Herzegovina.
authors.forename: Slavka
authors.initials: S
authors.lastname: Ibrulj
authors.forename: Sanin
authors.initials: S
authors.lastname: Haverić
authors.forename: Anja
authors.initials: A
authors.lastname: Haverić
authors.forename: Adaleta
authors.initials: A
authors.lastname: Durmić-Pasić
authors.forename: Damir
authors.initials: D
authors.lastname: Marjanović
mesh_terms: D017522:Bosnia and Herzegovina / Q000453:epidemiology; D002467:Cell Nucleus / Q000648:ultrastructure; D003627:Data Interpretation, Statistical; D005260:Female; D040741:Genetic Load; D006801:Humans; D008214:Lymphocytes / Q000648:ultrastructure; D008297:Male; D015162:Micronucleus Tests; D009153:Mutagens / Q000633:toxicity*; D009369:Neoplasms / Q000453:epidemiology; D012737:Sex Factors; D012907:Smoking; D014857:Warfare
chemical_list: D009153:Mutagens