[Follicular keratosis and multiple myeloma].
Follicular keratosis may be a rare paraneoplastic disease having unknown etiopathogeny that is sometimes associated to myeloma whose diagnosis and evolution follow a parallel course. We describe the case of a 57-year-old female patient diagnosed of multiple myeloma 8 years ago. She developed generalized follicular hyperkeratotic spicules coinciding with leukemization of the myeloma.
García-Romero
D
D
Servicio de Dermatología, Hospital Universitario 12 de Octubre, Ctra. de Andalucia km. 5,4. 28041 Madrid, Spain. dianadic78@yahoo.es
Sanz-Robles
H
H
Arrue
I
I
Sánchez-Largo
M E
ME
Rodríguez-Peralto
J L
JL
Vanaclocha
F
F
D000970:Antineoplastic Agents / Q000627:therapeutic use; D001897:Boronic Acids / Q000627:therapeutic use; D000069286:Bortezomib; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007641:Keratolytic Agents / Q000627:therapeutic use; D007642:Keratosis / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D008875:Middle Aged; D009101:Multiple Myeloma / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D011719:Pyrazines / Q000627:therapeutic use; D012867:Skin / Q000473:pathology
D000970:Antineoplastic Agents; D001897:Boronic Acids; D007641:Keratolytic Agents; D011719:Pyrazines; D000069286:Bortezomib