title: HIV-hepatitis C virus co-infection is associated with decreased plasmatic IL-7 levels.
abstract: We analysed the potential influence of hepatitis C virus (HCV) co-infection over IL-7 levels and thymic function in naive HIV-infected patients and after effective HAART. HIV-HCV-co-infected patients had lower plasmatic IL-7 levels compared with HIV-monoinfected patients. This effect may not be associated either with HCV monoinfection or with the rate of liver injury. These lower levels may explain, at least partly, the lower CD4 cell repopulation of HIV-HCV-co-infected patients after HAART.
authors.affiliation: Viral Hepatitis and AIDS Unit, Spain.
authors.forename: Natalia
authors.initials: N
authors.lastname: Soriano-Sarabia
authors.forename: Alejandro
authors.initials: A
authors.lastname: Vallejo
authors.forename: Sonia
authors.initials: S
authors.lastname: Molina-Pinelo
authors.forename: Miguel
authors.initials: M
authors.lastname: Genebat
authors.forename: María
authors.initials: M
authors.lastname: del Mar Rodríguez
authors.forename: Armando
authors.initials: A
authors.lastname: Sánchez-Quijano
authors.forename: Manuel
authors.initials: M
authors.lastname: Martínez-Moya
authors.forename: Jorge
authors.initials: J
authors.lastname: Vivancos
authors.forename: Manuel
authors.initials: M
authors.lastname: Leal
mesh_terms: D023241:Antiretroviral Therapy, Highly Active; D018791:CD4 Lymphocyte Count; D005260:Female; D015658:HIV Infections / Q000150:complications / Q000188:drug therapy / Q000276:immunology*; D019698:Hepatitis C, Chronic / Q000150:complications / Q000276:immunology*; D006801:Humans; D015851:Interleukin-7 / Q000097:blood*; D008297:Male
chemical_list: D015851:Interleukin-7