title: How to improve bilio-stasis in liver surgery.
abstract: One of the most fearful complications following hepatic resection is the onset of a biliary fistula. We have attempted to improve intraoperative bilio-stasis to minimize the risk of postoperative fistula development by testing different materials. In the early 2005 we began employing a collagen sponge coated with fibrinogen and thrombin (Tachosil) In our clinical experience, prior to sponge use, a biliary fistula developed in 3.9% of elective resections and 5.1% of surgical procedures for liver trauma. Until now there were no postoperative bile leaks in the patients treated with Tachosil.
authors.affiliation: Chirurgia 2, Dipartimento di Chirurgia Generale 2, Ospedale Regionale di Bolzano.
authors.forename: Antonio
authors.initials: A
authors.lastname: Frena
authors.forename: Federico
authors.initials: F
authors.lastname: Martin
mesh_terms: D001658:Biliary Fistula / Q000209:etiology* / Q000517:prevention & control*; D001662:Biliary Tract Surgical Procedures / Q000009:adverse effects / Q000379:methods; D003094:Collagen / Q000008:administration & dosage; D004359:Drug Therapy, Combination; D005340:Fibrinogen / Q000008:administration & dosage; D006490:Hemostatics / Q000008:administration & dosage*; D006498:Hepatectomy / Q000009:adverse effects* / Q000379:methods*; D006801:Humans; D008107:Liver Diseases / Q000601:surgery; D015503:Surgical Sponges; D013917:Thrombin / Q000008:administration & dosage; D016896:Treatment Outcome
chemical_list: D006490:Hemostatics; D005340:Fibrinogen; D003094:Collagen; D013917:Thrombin