Nutrition and cancer risk: an overview.
The role of diet in cancer is a major public health issue Foods associated with a low risk of cancer are those typically included in the so-called Mediterranean diet, which is also associated with low mortality rates from cardiovascular disease. Implementing such a diet would involve increasing the consumption of fruits, vegetables, cereals, whole-grain foods and fish, while reducing the intake of refined carbohydrates and red meat. In addition, olive oil should replace saturated fats. Omega-3 fatty acids found in fish inhibit the growth in vitro of colon, breast and prostate cancers. Fibre can bind bile acids, which produce carcinogenic metabolites, and fermented fibre produces volatile fatty acids that can protect against colon cancer. It has been hypothesized that the anti-cancer actions of olive oil may relate to the ability of its mono-unsaturated fatty acid, oleic acid, to regulate oncogenes.
Fernández
Esteve
E
Cancer Prevention and Control Unit, Institut Català d'Oncologia, Barcelona, Spain. efernandez@ico.scs.es
Gallus
Silvano
S
La Vecchia
Carlo
C
D038441:Diet, Mediterranean; D004041:Dietary Fats / Q000008:administration & dosage; D004043:Dietary Fiber / Q000008:administration & dosage; D005638:Fruit; D006801:Humans; D008460:Meat; D009369:Neoplasms / Q000453:epidemiology / Q000517:prevention & control*; D012306:Risk; D017747:Seafood; D014675:Vegetables
D004041:Dietary Fats; D004043:Dietary Fiber