title: Estrogens and aspects of prostate disease.
abstract: Estrogens have long been associated with the processes involved in prostate carcinogenesis, particularly in cancer suppression. However, the synergistic influence of low concentrations of estrogens, together with androgens, in promoting aberrant growth of the gland has also been recognized. As new insights into the complex molecular events implicated in growth regulation of the prostate are revealed, the role of the estrogens has become clearer. The present review considers this role in relation to the pathogenesis of prostate cancer and the potential cancer-repressive influence of the dietary estrogens.
authors.affiliation: Oncology Center, Antwerpen, Belgium.
authors.forename: Domenico
authors.initials: D
authors.lastname: Prezioso
authors.forename: Louis J
authors.initials: LJ
authors.lastname: Denis
authors.forename: Helmut
authors.initials: H
authors.lastname: Klocker
authors.forename: Alexandria
authors.initials: A
authors.lastname: Sciarra
authors.forename: Mario
authors.initials: M
authors.lastname: Reis
authors.forename: Kurt
authors.initials: K
authors.lastname: Naber
authors.forename: Bernard
authors.initials: B
authors.lastname: Lobel
authors.forename: Dalibor
authors.initials: D
authors.lastname: Pacik
authors.forename: Keith
authors.initials: K
authors.lastname: Griffiths
mesh_terms: D004967:Estrogens / Q000009:adverse effects / Q000502:physiology*; D006801:Humans; D008297:Male; D017410:Practice Guidelines as Topic; D011469:Prostatic Diseases / Q000188:drug therapy / Q000209:etiology*; D011471:Prostatic Neoplasms / Q000209:etiology* / Q000235:genetics; D011472:Prostatitis / Q000209:etiology
chemical_list: D004967:Estrogens