title: [Allergy to latex gloves among healthcare workers in Dakar].
abstract: BACKGROUND
  The prevalence of latex allergy is high (to 17%) among groups at risk such healthcare workers. Our aim was to determine the prevalence and severity of allergy to latex gloves among health workers in Dakar.
  
  
  METHODS
  The study was conducted in three of the five hospitals in Dakar (Senegal). A randomized sample was constituted. All healthcare workers required to use latex gloves in their work were included. A questionnaire was administered. The analysis was performed using the Epi-info software package (6.0).
  
  
  RESULTS
  One hundred and forty cases were included. The median age was 39 years and the sex-ratio was 0.57. Sixty-six (47%) cases had familial atopic dermatitis, 13 (9.6%) had atopic dermatitis, and 4 (2.9%) indicated food allergy (banana, avocado). Irritant dermatitis was found in 40.7% of cases, 112 healthcare workers (81.2%) used bleach and water to clean their hands. Antiseptics were used frequently: 75.5% of those interviewed used them more than three times a day. None of the healthcare workers indicated any allergy to latex condoms. Otherwise surgical procedures and bladder/rectal catheters were noted respectively in 24% and 18% cases. Fifteen healthcare workers (10.7%), of whom 12 were women, indicated appearance of clinical signs when using latex gloves. The clinical manifestations were: contact urticaria or immediate pruritus (8 cases), combined contact dermatitis and contact urticaria (2 cases), allergic conjunctivitis (1 case), allergic rhinitis (2 cases) and asthma (2 cases). We also noted 6 cases of contact dermatitis. Rechallenge tests were performed in 7 cases and were positive, 2/3 prick-tests and 1/4 patch-tests (standard European battery). The statistical analysis shows that allergy to latex gloves was significantly associated with atopy and irritant dermatitis (p<0.03).
  
  
  CONCLUSIONS
  We found a prevalence of allergy to latex gloves of 11% among healthcare workers in Dakar, reflecting reports in the literature. The classical risk factors such atopic dermatitis and irritant dermatitis were found. The correlation between irritant dermatitis and frequent use of bleach and water mean that these practices should be eradicated since they play an important role in the development of contact urticaria and anaphylactic reactions.
authors.affiliation: Service de Dermatologie, IST de l'Institut d'Hygiène Social, Dakar, Sénégal. lyfaty@yahoo.fr
authors.forename: F
authors.initials: F
authors.lastname: Ly
authors.forename: I
authors.initials: I
authors.lastname: Mbaye
authors.forename: I
authors.initials: I
authors.lastname: Wone
authors.forename: C
authors.initials: C
authors.lastname: Gaye-Fall
authors.forename: M-L M
authors.initials: ML
authors.lastname: Sow
authors.forename: B
authors.initials: B
authors.lastname: Ndiaye
authors.forename: A
authors.initials: A
authors.lastname: Mahé
mesh_terms: D000328:Adult; D003876:Dermatitis, Atopic / Q000453:epidemiology; D017453:Dermatitis, Irritant / Q000453:epidemiology; D005260:Female; D006282:Health Personnel; D006801:Humans; D020315:Latex Hypersensitivity / Q000453:epidemiology*; D008297:Male; D009784:Occupational Diseases / Q000453:epidemiology*; D012307:Risk Factors; D012675:Senegal / Q000453:epidemiology; D011795:Surveys and Questionnaires