title: [Impact of the working environment on metabolic reactions in operating pilots].
abstract: Two groups of male volunteers aged 35-45 years were examined. Group 1 comprised 20 healthy donors controls) and Group 2 included 10 operating pilots whom after biochemical blood analysis were proposed to use daily the biologically active supplement (BAS) Kalifen, 5 ml (which was equal to 100 mg/day of total polyphenols) after meals in the morning for 4 weeks. Before the use of the supplement, the sera of the examinees provided evidence that they had hypertriglyceridemia and hypercholesterolemia, inhibited hepatic etherifying function, unbalanced phospholipid composition, depleted antioxidative system, enhanced lipid peroxidation, and increased erythrocytic membrane permeability. The combined influence of the working environment on the operating pilots's health status appeared as pronounced metabolic changes characteristic of those observed under physical and emotional stress. The use of Kalifen facilitated normalization of the studied biochemical parameters. From the afore-said, it is advisable to use BAS for the prevention of stress actions caused by a variety of physical and emotional agents.
authors.forename: N F
authors.initials: NF
authors.lastname: Kushnerova
authors.forename: Iu A
authors.initials: IuA
authors.lastname: Rakhmanin
authors.forename: S E
authors.initials: SE
authors.lastname: Fomenko
authors.forename: T L
authors.initials: TL
authors.lastname: Chizhova
authors.forename: A A
authors.initials: AA
authors.lastname: Sheparev
mesh_terms: D000328:Adult; D015415:Biomarkers / Q000097:blood*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009326:Naval Medicine; D009784:Occupational Diseases / Q000097:blood* / Q000209:etiology; D016273:Occupational Exposure / Q000009:adverse effects*; D018384:Oxidative Stress / Q000502:physiology; D011379:Prognosis; D012307:Risk Factors; D013315:Stress, Psychological / Q000097:blood* / Q000150:complications
chemical_list: D015415:Biomarkers