title: No apparent association between ocular perfusion pressure and visual field damage in normal-tension glaucoma patients.
abstract: OBJECTIVE
  To investigate the correlation of ocular perfusion pressure (OPP) with general and localized visual field damage in normal-tension glaucoma (NTG) patients.
  
  
  METHODS
  Correlations between OPP, blood pressure, age, intraocular pressure, refractive error, and extent of visual field damage in the eye with the worst mean deviation (MD) were investigated retrospectively in 94 eyes of 94 NTG patients. Visual fields were analyzed statistically with respect to 15 sectors between two age-matched groups of subjects with high or low OPP.
  
  
  RESULTS
  Significant positive correlations were found between OPP and age (P < 0.001), blood pressure and age (P < 0.05), and MD and refractive error (P < 0.01). OPP had no significant correlation with MD or mean sensitivity in the visual field in any of the visual field sectors.
  
  
  CONCLUSIONS
  OPP and systemic blood pressure have no evident effect on the extent or pattern of visual field damage in NTG.
authors.affiliation: Department of Ophthalmology, University of Tokyo Graduate School of Medicine, Tokyo, Japan.
authors.forename: Naoyuki
authors.initials: N
authors.lastname: Kurita
authors.affiliation: Department of Ophthalmology, University of Tokyo Graduate School of Medicine, Tokyo, Japan.
authors.forename: Atsuo
authors.initials: A
authors.lastname: Tomidokoro
authors.affiliation: Department of Ophthalmology, Saitama Red Cross Hospital, Saitama, Japan. cmayama-tky@umin.ac.jp.
authors.forename: Chihiro
authors.initials: C
authors.lastname: Mayama
authors.affiliation: Department of Ophthalmology, University of Tokyo Graduate School of Medicine, Tokyo, Japan.
authors.forename: Makoto
authors.initials: M
authors.lastname: Aihara
authors.affiliation: Department of Ophthalmology, University of Tokyo Graduate School of Medicine, Tokyo, Japan.
authors.forename: Makoto
authors.initials: M
authors.lastname: Araie
mesh_terms: D000293:Adolescent; D000328:Adult; D001794:Blood Pressure / Q000502:physiology*; D005123:Eye / Q000098:blood supply*; D005902:Glaucoma, Open-Angle / Q000503:physiopathology*; D006801:Humans; D007429:Intraocular Pressure; D008875:Middle Aged; D010477:Perfusion; D014786:Vision Disorders / Q000503:physiopathology*; D014794:Visual Fields / Q000502:physiology*