title: A highly enantio- and diastereoselective 1,3-dimethylallylation of aldehydes.
abstract: A highly enantio- and diastereoselective pentenylation of aldehydes is described. The homoallylic alcohol derived from 1,3-dimethylallylation of (-)-menthone undergoes an efficient allyl-transfer reaction with a wide range of aliphatic aldehydes in the presence of an acid catalyst to give rise to the corresponding 4-methyl-2(E)-penten-4-yl-5-ol products in good yields with high enantio- and 4,5-syn-selectivities.
authors.affiliation: Department of Chemistry, Princeton University, Princeton, NJ 08544, USA.
authors.forename: Yu
authors.initials: Y
authors.lastname: Yuan
authors.forename: Amy J
authors.initials: AJ
authors.lastname: Lai
authors.forename: Christina M
authors.initials: CM
authors.lastname: Kraml
authors.forename: Chulbom
authors.initials: C
authors.lastname: Lee