Adrenaline-induced digital ischaemia reversed with phentolamine.
Adrenaline autoinjectors are widely prescribed for self-treatment of anaphylactic syndromes. Accidental misfire into digits can cause prolonged significant ischaemia with serious outcomes. Phentolamine is a readily available treatment, which is easily and safely given in the emergency setting.
Molony
Darren
D
Department of Plastic and Reconstructive Surgery, Royal Adelaide Hospital, Adelaide, South Australia, Australia. darren@apsa.com.au
D000316:Adrenergic alpha-Agonists / Q000008:administration & dosage / Q000009:adverse effects*; D000317:Adrenergic alpha-Antagonists / Q000627:therapeutic use*; D000328:Adult; D001340:Autonomic Nerve Block; D004837:Epinephrine / Q000008:administration & dosage / Q000009:adverse effects*; D005385:Fingers / Q000098:blood supply*; D006801:Humans; D007267:Injections; D007511:Ischemia / Q000139:chemically induced / Q000188:drug therapy*; D008297:Male; D010646:Phentolamine / Q000627:therapeutic use*
D000316:Adrenergic alpha-Agonists; D000317:Adrenergic alpha-Antagonists; D004837:Epinephrine; D010646:Phentolamine