Characterization and bioscreening of a new triterpenoid and a flavanone isolated from Salvia nubicola.
A new epimeric lupane triterpenoid, 3alpha-hydroxy-20-oxo-30-norlupane (1), and a new flavanone (nubatin; 3) have been isolated from Salvia nubicola collected from Quetta, Pakistan. The structures of these constituents were elucidated with the aid of spectroscopic techniques, including two-dimensional NMR and NOE experiments. Both the metabolites were found to be moderately bio-active.
Ali
Muhammad S
MS
H. E. J. Research Institute of Chemistry, International Center for Chemical Sciences, University of Karachi, Karachi-75270, Pakistan. shaiq303@hotmail.com
Ahmed
Shakeel
S
Ibrahim
Syed A
SA
Tareen
Rasool B
RB
D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000494:pharmacology; D000935:Antifungal Agents / Q000737:chemistry / Q000494:pharmacology; D029064:Araceae / Q000187:drug effects; D044950:Flavanones / Q000737:chemistry* / Q000494:pharmacology*; D047309:Flavones / Q000737:chemistry* / Q000494:pharmacology*; D006540:Herbicides / Q000737:chemistry / Q000494:pharmacology; D015394:Molecular Structure; D027544:Salvia / Q000737:chemistry*; D014315:Triterpenes / Q000737:chemistry* / Q000494:pharmacology*
C516964:3-hydroxy-20-oxo-30-norlupane; D000900:Anti-Bacterial Agents; D000935:Antifungal Agents; D044950:Flavanones; D047309:Flavones; D006540:Herbicides; D014315:Triterpenes; C516963:nubatin