title: Common variable immunodeficiency patient with large granular lymphocytosis developing extranodal diffuse large B-cell lymphoma: a case report.
abstract: Here we describe a Common Variable Immunodeficiency (CVI) patient with large granular (LG) lymphocytosis and systemic non-malignant lymphadenopathy who developed diffuse large B-cell lymphoma of the stomach. This is the first report of gastric high-grade lymphoma with widespread lymphadenopathy in a patient with LG lymphocytosis associated with CVI.
authors.affiliation: Hematology Unit, University of Bari School of Medicine, Bari, Italy. mario.delia@tiscalinet.it
authors.forename: Mario
authors.initials: M
authors.lastname: Delia
authors.forename: Vincenzo
authors.initials: V
authors.lastname: Liso
authors.forename: Silvana
authors.initials: S
authors.lastname: Capalbo
authors.forename: Anna
authors.initials: A
authors.lastname: Napoli
authors.forename: Rosalia
authors.initials: R
authors.lastname: Ricco
authors.forename: Gianpietro
authors.initials: G
authors.lastname: Semenzato
authors.forename: Arcangelo
authors.initials: A
authors.lastname: Liso
mesh_terms: D000328:Adult; D001402:B-Lymphocytes / Q000473:pathology; D017074:Common Variable Immunodeficiency / Q000150:complications* / Q000601:surgery; D006801:Humans; D016130:Immunophenotyping; D008198:Lymph Nodes / Q000473:pathology; D008218:Lymphocytosis / Q000209:etiology* / Q000473:pathology; D016403:Lymphoma, Large B-Cell, Diffuse / Q000209:etiology* / Q000473:pathology; D008228:Lymphoma, Non-Hodgkin / Q000209:etiology / Q000473:pathology; D008297:Male; D011183:Postoperative Complications / Q000209:etiology / Q000473:pathology; D013156:Splenectomy; D013274:Stomach Neoplasms / Q000209:etiology* / Q000473:pathology; D013601:T-Lymphocytes / Q000473:pathology