Common variable immunodeficiency patient with large granular lymphocytosis developing extranodal diffuse large B-cell lymphoma: a case report.
Here we describe a Common Variable Immunodeficiency (CVI) patient with large granular (LG) lymphocytosis and systemic non-malignant lymphadenopathy who developed diffuse large B-cell lymphoma of the stomach. This is the first report of gastric high-grade lymphoma with widespread lymphadenopathy in a patient with LG lymphocytosis associated with CVI.
Delia
Mario
M
Hematology Unit, University of Bari School of Medicine, Bari, Italy. mario.delia@tiscalinet.it
Liso
Vincenzo
V
Capalbo
Silvana
S
Napoli
Anna
A
Ricco
Rosalia
R
Semenzato
Gianpietro
G
Liso
Arcangelo
A
D000328:Adult; D001402:B-Lymphocytes / Q000473:pathology; D017074:Common Variable Immunodeficiency / Q000150:complications* / Q000601:surgery; D006801:Humans; D016130:Immunophenotyping; D008198:Lymph Nodes / Q000473:pathology; D008218:Lymphocytosis / Q000209:etiology* / Q000473:pathology; D016403:Lymphoma, Large B-Cell, Diffuse / Q000209:etiology* / Q000473:pathology; D008228:Lymphoma, Non-Hodgkin / Q000209:etiology / Q000473:pathology; D008297:Male; D011183:Postoperative Complications / Q000209:etiology / Q000473:pathology; D013156:Splenectomy; D013274:Stomach Neoplasms / Q000209:etiology* / Q000473:pathology; D013601:T-Lymphocytes / Q000473:pathology