De novo grown bone on exposed implant surfaces using photodynamic therapy and recombinant human bone morphogenetic protein-2: case report.
The reconstruction of bone on exposed implant surfaces requires an almost complete elimination of attached bacteria. Only then is new bone growth possible. This case report describes a new way to kill biofilms with photodynamic therapy and to augment bone by using recombinant human bone morphogenetic protein-2. Though the new technique of bone tissue engineering causes some problems, new bone growth on uncovered implant surfaces is successful to a large extent.
Schuckert
Karl-Heinz
KH
INDENTE-Institute of Innovative Oral Surgery and Medicine, Centre for Tissue Engineering, Hanover, Germany. info@indente.de
Jopp
Stefan
S
Muller
Ulrich
U
D000328:Adult; D016301:Alveolar Bone Loss / Q000188:drug therapy / Q000209:etiology; D055396:Bone Morphogenetic Protein 2; D019485:Bone Morphogenetic Proteins / Q000627:therapeutic use*; D015921:Dental Implants / Q000009:adverse effects; D004337:Drug Carriers; D005260:Female; D005500:Follow-Up Studies; D005781:Gelatin Sponge, Absorbable; D006801:Humans; D053685:Laser Therapy; D010012:Osteogenesis / Q000187:drug effects*; D010518:Periodontitis / Q000188:drug therapy / Q000209:etiology; D010778:Photochemotherapy; D016212:Transforming Growth Factor beta / Q000627:therapeutic use*
C525718:BMP2 protein, human; D055396:Bone Morphogenetic Protein 2; D019485:Bone Morphogenetic Proteins; D015921:Dental Implants; D004337:Drug Carriers; D016212:Transforming Growth Factor beta