title: Leading-edge research: PtdIns(3,4,5)P3 and directed migration.
authors.forename: Jonathan
authors.initials: J
authors.lastname: Franca-Koh
authors.forename: Yoichiro
authors.initials: Y
authors.lastname: Kamimura
authors.forename: Peter N
authors.initials: PN
authors.lastname: Devreotes
mesh_terms: D000818:Animals; D002633:Chemotaxis; D058544:Class Ib Phosphatidylinositol 3-Kinase; D006801:Humans; D000072181:Inositol Polyphosphate 5-Phosphatases; D007527:Isoenzymes / Q000235:genetics / Q000378:metabolism / Q000502:physiology; D051379:Mice; D008954:Models, Biological; D009504:Neutrophils / Q000201:enzymology / Q000502:physiology*; D051059:PTEN Phosphohydrolase / Q000235:genetics / Q000502:physiology; D019869:Phosphatidylinositol 3-Kinases / Q000235:genetics / Q000378:metabolism / Q000502:physiology; D018129:Phosphatidylinositol Phosphates / Q000378:metabolism*; D010744:Phosphoric Monoester Hydrolases / Q000235:genetics / Q000378:metabolism / Q000502:physiology*
chemical_list: D007527:Isoenzymes; D018129:Phosphatidylinositol Phosphates; C060974:phosphatidylinositol 3,4,5-triphosphate; D019869:Phosphatidylinositol 3-Kinases; D058544:Class Ib Phosphatidylinositol 3-Kinase; C546760:PIK3CG protein, human; C546764:Pik3cg protein, mouse; D010744:Phosphoric Monoester Hydrolases; D000072181:Inositol Polyphosphate 5-Phosphatases; D051059:PTEN Phosphohydrolase