title: [A case of progressive gastric carcinoma accompanied by disseminated carcinomatosis of bone marrow due to bone metastasis with DIC recovery by joint administration of 5-FU and paclitaxel].
abstract: A 54-year-old male visited our hospital with the chief complaint of anorexia. Based on various tests, a diagnosis of scirrhous gastric carcinoma accompanied by bone metastasis and liver metastasis was made. As DIC developed following hospital admission, 5-FU and PTX therapy (5-FU at 600 mg/m(2), 24-hour continuous infusion, day 1-5 and PTX at 80 mg/m(2), iv, day 8, 15, 22) were administered. Although primary foci, bone metastasis, and liver metastasis were observed by image diagnostic procedures, recovery from DIC was achieved. 5-FU+PTX therapy is considered to be effective for DIC due to bone metastasis of gastric carcinoma.
authors.affiliation: Dept. of Surgery, Hiroshima City Hospital.
authors.forename: Daisuke
authors.initials: D
authors.lastname: Satoh
authors.forename: Motoki
authors.initials: M
authors.lastname: Ninomiya
authors.forename: Tatsuya
authors.initials: T
authors.lastname: Umeoka
authors.forename: Masao
authors.initials: M
authors.lastname: Harano
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Sasaki
authors.forename: Hideki
authors.initials: H
authors.lastname: Aoki
authors.forename: Tadashi
authors.initials: T
authors.lastname: Onoda
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Shiozaki
authors.forename: Satoru
authors.initials: S
authors.lastname: Ohno
authors.forename: Kenji
authors.initials: K
authors.lastname: Higaki
authors.forename: Naohisa
authors.initials: N
authors.lastname: Takakura
mesh_terms: D002293:Adenocarcinoma, Scirrhous / Q000188:drug therapy* / Q000556:secondary; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D019046:Bone Marrow Neoplasms / Q000188:drug therapy* / Q000556:secondary; D001859:Bone Neoplasms / Q000188:drug therapy* / Q000556:secondary; D004211:Disseminated Intravascular Coagulation / Q000209:etiology*; D004334:Drug Administration Schedule; D005472:Fluorouracil / Q000008:administration & dosage; D006801:Humans; D008113:Liver Neoplasms / Q000188:drug therapy* / Q000556:secondary; D008297:Male; D008875:Middle Aged; D017239:Paclitaxel / Q000008:administration & dosage; D013274:Stomach Neoplasms / Q000188:drug therapy* / Q000473:pathology*
chemical_list: D017239:Paclitaxel; D005472:Fluorouracil