title: Hypertension and its management: a problem in need of new treatment strategies.
abstract: Although treatments of hypertension have significantly decreased morbidity and mortality from cerebrovascular disease, the associated reductions in coronary artery disease have been very disappointing. Hypertension is a complex inherited syndrome of cardiovascular risk factors, all of which contribute to the development of heart disease. Angiotensin II receptor blockers (ARBs), such as the highly selective ARB valsartan, provide an alternative treatment strategy to address the multiple issues in coronary artery disease. These agents are well-tolerated and have a once-daily regimen that improves compliance. They bring multiple cardiovascular benefits beyond blood pressure (BP) control, such as renoprotection and cardiovascular growth reduction.
authors.affiliation: Veterans Affairs Medical Center, Long Beach, Calfornia, USA. JMNeutel@aol.com
authors.forename: J M
authors.initials: JM
authors.lastname: Neutel
mesh_terms: D000959:Antihypertensive Agents / Q000627:therapeutic use*; D050197:Atherosclerosis / Q000150:complications / Q000628:therapy; D001794:Blood Pressure / Q000187:drug effects; D004359:Drug Therapy, Combination; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000188:drug therapy* / Q000453:epidemiology / Q000503:physiopathology; D010349:Patient Compliance; D012307:Risk Factors
chemical_list: D000959:Antihypertensive Agents