title: Comparison of nonuniform rotational distortion between mechanical IVUS and OCT using a phantom model.
abstract: Optical coherence tomography (OCT) is an optical analog of mechanical intravascular ultrasound (M-IVUS) with much higher spatial resolution. However, no data exist regarding the nonuniform rotational distortion (NURD) with OCT. The aim of the study was to investigate whether OCT generates less NURD relative to M-IVUS. A coronary artery phantom model was constructed with a rubber ring (3.68 mm in diameter), located at the distal end of the phantom. This model was also composed of eight equally spaced steel wires and an additional marker-wire. Two types of vascular phantoms were used, mild curve (90 degrees ) and acute curve (near 180 degrees ). Subsequent M-IVUS (n = 6) and OCT (n = 6) imaging was performed. Eight angles between eight wires, except the marker-wire, were measured from each image. These angles, measured with M-IVUS and OCT, were compared with those of high-resolution optical photography as a gold standard. The average in angle differences was significantly smaller in OCT compared with M-IVUS in the mild curve model (3.2 +/- 1.0 degrees vs, 6.9 +/- 2.1 degrees , p < 0.01). Compared with the latter model, the average in angle differences was exaggerated in the acute curve model with M-IVUS (9.1 +/- 0.9 degrees vs. 6.9 +/- 2.1 degrees , p < 0.05) but not with OCT (3.5 +/- 0.8 degrees vs. 3.2 +/- 1.0 degrees , p= not significant). OCT generates significantly less NURD compared with M-IVUS, especially in tortuous situation.
authors.affiliation: Cardiology Laboratory of Integrative Physiology and Imaging, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.
authors.forename: Yoshiaki
authors.initials: Y
authors.lastname: Kawase
authors.forename: Yoriyasu
authors.initials: Y
authors.lastname: Suzuki
authors.forename: Fumiaki
authors.initials: F
authors.lastname: Ikeno
authors.forename: Ryuichi
authors.initials: R
authors.lastname: Yoneyama
authors.forename: Kozo
authors.initials: K
authors.lastname: Hoshino
authors.forename: Hung Q
authors.initials: HQ
authors.lastname: Ly
authors.forename: George T
authors.initials: GT
authors.lastname: Lau
authors.forename: Motoya
authors.initials: M
authors.lastname: Hayase
authors.forename: Alan C
authors.initials: AC
authors.lastname: Yeung
authors.forename: Roger J
authors.initials: RJ
authors.lastname: Hajjar
authors.forename: Ik-Kyung
authors.initials: IK
authors.lastname: Jang
mesh_terms: D016477:Artifacts; D002404:Catheterization; D003331:Coronary Vessels / Q000000981:diagnostic imaging*; D004867:Equipment Design; D006801:Humans; D019047:Phantoms, Imaging; D012399:Rotation; D041623:Tomography, Optical Coherence / Q000295:instrumentation / Q000379:methods*; D018084:Ultrasonography, Interventional / Q000295:instrumentation / Q000379:methods*