[Autowave mode of functioning of the system nitric oxide + free iron + thiols may ensure the regulation of biological action of nitric oxide and its endogenic compounds].
It has been shown earlier that, in a system NO + Fe2+ + thiols in aqueous solution, an oscillatory mode of changes with time in the concentration of paramagnetic dinitrosyl iron complexes with thiol-containing legends and S-nitrosothiols formed in this system and in the concentration of free iron (not included into dinitrosyl iron complexes) can be realized. It is assumed that, in this system, autowaves can arise, which ensure periodic changes with time and space in the concentration of the system constituents. These changes may underlie the regulation of the physiologic effect of nitric oxide, dinitrosyl iron complexes, and S-nitrosothiols as agents affecting various intracellular and tissue targets.
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D055592:Biophysical Phenomena; D001703:Biophysics; D007501:Iron / Q000737:chemistry*; D008954:Models, Biological; D009569:Nitric Oxide / Q000737:chemistry* / Q000502:physiology*; D012996:Solutions; D013438:Sulfhydryl Compounds / Q000737:chemistry*; D014867:Water / Q000737:chemistry*
D012996:Solutions; D013438:Sulfhydryl Compounds; D014867:Water; D009569:Nitric Oxide; D007501:Iron