[Improved method of acute myocardial ischemic rat model].
OBJECTIVE
To improve the successful rate of operation and the livability in establishing acute myocardial ischemic rat model.


METHODS
The successful rate of animal experiment is compared between traditional method and improved method.


RESULTS
The successful rate of improved method was 90%, which was much higher than 30% in successful rate of traditional method.


CONCLUSIONS
The improved method may reduce the difficulty of operation remarkably and cut down the experiment expenditure, which is superior to traditional method.
Luo
Bin
B
Department of Forensic Medicine, The School of Preclinical Medicine, Sun Yat-sen University, Guangzhou 510080, China. luobin@mail.sysu.edu.cn
Xiang
Lei
L
Jiang
Dong-Hua
DH
Kong
Xiao-Ping
XP
Zhang
Neng-Pei
NP
He
Yun
Y
Zhang
Bin
B
Yang
Yu
Y
Cheng
Ling-Xi
LX
D000208:Acute Disease; D000768:Anesthesia, General / Q000379:methods*; D000818:Animals; D003331:Coronary Vessels / Q000601:surgery*; D004195:Disease Models, Animal; D007442:Intubation, Intratracheal / Q000379:methods*; D007649:Ketamine / Q000008:administration & dosage / Q000737:chemistry; D008297:Male; D017202:Myocardial Ischemia / Q000473:pathology*; D051381:Rats; D017207:Rats, Sprague-Dawley
D007649:Ketamine