Glycosylation in room temperature ionic liquid using unprotected and unactivated donors.
Glycosylation in room temperature ionic liquid is demonstrated using unprotected and unactivated donors. Modest yields of simple benzyl glycosides and disaccharides of glucose, mannose and N-acetylgalactosamine were obtained in 1-ethyl-3-methylimidazolium benzoate with Amberlite IR-120 (H(+)) resin or p-toluenesulfonic acid as promoters.
Park
Tae-Joon
TJ
Department of Chemical and Biological Engineering, Biotechnology 4005, Rensselaer Polytechnic Institute, 110, 8th Street, Troy, NY 12180, USA.
Weïwer
Michel
M
Yuan
Xuejun
X
Baytas
Sultan N
SN
Munoz
Eva M
EM
Murugesan
Saravanababu
S
Linhardt
Robert J
RJ
D000116:Acetylgalactosamine / Q000737:chemistry; D001557:Benzenesulfonates; D002240:Carbohydrate Sequence; D002411:Cation Exchange Resins; D004187:Disaccharides / Q000138:chemical synthesis*; D005947:Glucose / Q000737:chemistry; D006027:Glycosides / Q000138:chemical synthesis*; D006031:Glycosylation; D007093:Imidazoles / Q000737:chemistry*; D008358:Mannose / Q000737:chemistry; D008969:Molecular Sequence Data; D011137:Polystyrenes; D021241:Spectrometry, Mass, Electrospray Ionization; D013696:Temperature
D001557:Benzenesulfonates; D002411:Cation Exchange Resins; D004187:Disaccharides; D006027:Glycosides; D007093:Imidazoles; D011137:Polystyrenes; C025242:Amberlite IR-120; D005947:Glucose; D000116:Acetylgalactosamine; D008358:Mannose; C029501:4-toluenesulfonic acid; C518739:1-ethyl-3-methylimidazolium