title: Giant cell angiofibroma of the orbit with periosteal adherence.
abstract: We report a case of orbital giant cell angiofibroma, an unusual, recently reported benign spindle cell neoplasm. Preoperative clinical assessment and radiology suggested a benign mass and early operative findings were in concordance with this. Surgical excision was however, hampered by periosteal adhesion and lack of distinct encapsulation in the posterior part of the lesion. The histology of giant cell angiofibroma and its principle pathological differential diagnoses is discussed. As with some lymphangiomas, this is another benign orbital tumour which may present difficulties in complete surgical excision that are not anticipated based on the preoperative findings.
authors.affiliation: CorneoPlastic Unit, Queen Victoria Hospital, East Grinstead, UK.
authors.forename: Jean-Louis
authors.initials: JL
authors.lastname: deSousa
authors.forename: George
authors.initials: G
authors.lastname: Meligonis
authors.forename: Raman
authors.initials: R
authors.lastname: Malhotra
mesh_terms: D000368:Aged; D018322:Angiofibroma / Q000175:diagnosis* / Q000601:surgery; D003937:Diagnosis, Differential; D005870:Giant Cell Tumors / Q000175:diagnosis* / Q000601:surgery; D006801:Humans; D008297:Male; D013508:Ophthalmologic Surgical Procedures; D009918:Orbital Neoplasms / Q000175:diagnosis* / Q000601:surgery; D010521:Periosteum / Q000473:pathology*; D000267:Tissue Adhesions; D014057:Tomography, X-Ray Computed