title: Seroepidemiological survey of morbillivirus infection in Kuril harbor seals (Phoca vitulina stejnegeri) of Hokkaido, Japan.
abstract: Serological analysis was performed to detect morbillivirus infection in Kuril harbor seals in Hokkaido, Japan. Serum samples were collected from the seals at Nosappu (231 sera), Akkeshi (16), and Erimo (75) between 1998 and 2005. Antibodies to phocine distemper virus (PDV) were detected by ELISA in seals from Nosappu and Erimo. Antibodies to PDV were found in 56% (5/9) of the sampled seals from Nosappu in 1998, versus only 5% (3/66) for 2003, 1% (1/79) for 2004, and 1% (1/77) for 2005. These suggest epidemic caused by the virus in or before 1998. As antibody-positive seals included juvenile seals in 2003 and 2005, sporadic infections of the virus are thought to have occurred in recent years. In Erimo, antibodies to PDV were found in 50% (14/28) of sampled seals in 2004, versus only 13% (1/8) for 1999, 7% (1/15) for 2003, and 0% (0/24) for 2005. These suggest sporadic infection by the virus before 2003 and the epizootic between after autumn in 2003, when samples of 2003 were collected, and 2004. Since antibodies to canine distemper virus (CDV) were detected in one adult seal from Nosappu in each year from 2003 to 2005, sporadic infections of the virus were suggested. There were no difference in incidence of seals with antibodies to the viruses between males and females and between juveniles and adults.
authors.affiliation: Laboratory of Wildlife Biology, Graduate School of Veterinary Medicine, Hokkaido University, Sapporo 060-0818, Japan.
authors.forename: Kei
authors.initials: K
authors.lastname: Fujii
authors.forename: Hiroki
authors.initials: H
authors.lastname: Sato
authors.forename: Chiharu
authors.initials: C
authors.lastname: Kakumoto
authors.forename: Mari
authors.initials: M
authors.lastname: Kobayashi
authors.forename: Sachiko
authors.initials: S
authors.lastname: Saito
authors.forename: Tatsuya
authors.initials: T
authors.lastname: Kariya
authors.forename: Yukiko
authors.initials: Y
authors.lastname: Watanabe
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Sakoda
authors.forename: Chieko
authors.initials: C
authors.lastname: Kai
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Kida
authors.forename: Masatsugu
authors.initials: M
authors.lastname: Suzuki
mesh_terms: D000375:Aging; D000820:Animal Diseases / Q000453:epidemiology / Q000821:virology*; D000818:Animals; D000914:Antibodies, Viral / Q000097:blood; D004216:Distemper / Q000097:blood / Q000453:epidemiology* / Q000821:virology; D018104:Distemper Virus, Phocine / Q000302:isolation & purification*; D005260:Female; D007564:Japan / Q000453:epidemiology; D008297:Male; D046049:Phoca / Q000821:virology*; D016036:Seroepidemiologic Studies
chemical_list: D000914:Antibodies, Viral