title: Bioavailability of vitamin A sources for cattle.
abstract: An experiment was conducted to evaluate the bioavailability of 5 sources of vitamin A. It was hypothesized that some vitamin A products have protective coatings that are more resistant than others to rumen destruction and that such protection would result in greater tissue concentrations of vitamin A. Fifty-three yearling Angus x Brahman cattle, consisting of 39 steers and 14 heifers, were stratified by BW and sex and randomly assigned to 6 high-concentrate diet groups receiving no vitamin A supplementation (control) or vitamin A supplemented from the following sources: Microvit A (Adisseo, Acworth, GA), Rovamix A (DSM, Parsippany, NJ), Sunvit A, Lutavit A, and Microvit A DLC (Adisseo). The vitamin A treatment groups were fed daily 80,000 IU of retinol/animal in a low-retinol concentrate diet (78.5% oats, 10% cottonseed hulls, 8% molasses, and 2% cottonseed meal; DM basis) and a free-choice, poor quality (low carotene) hay for 84 d. Every 28 d, BW was determined and liver biopsies and plasma were collected and analyzed for retinol concentrations. All retinol treatments showed significant increases in liver retinol concentrations compared with control animals (P < 0.0001), which steadily decreased over time. At all collection times, Microvit A led to numerically, but not significantly, greater concentrations of retinol in liver than did all other treatments. However, at the end of the experiment, there was no significant difference in liver retinol concentration among Microvit A, Rovamix A, Lutavit A, and Microvit A DLC diets. When liver retinol concentrations at all collection times were considered, Microvit A and Rovamix A appeared to provide the most bioavailable vitamin A.
authors.affiliation: Department of Animal Sciences, University of Florida-IFAS, Gainesville 32611, USA.
authors.forename: C E
authors.initials: CE
authors.lastname: Alosilla
authors.forename: L R
authors.initials: LR
authors.lastname: McDowell
authors.forename: N S
authors.initials: NS
authors.lastname: Wilkinson
authors.forename: C R
authors.initials: CR
authors.lastname: Staples
authors.forename: W W
authors.initials: WW
authors.lastname: Thatcher
authors.forename: F G
authors.initials: FG
authors.lastname: Martin
authors.forename: M
authors.initials: M
authors.lastname: Blair
mesh_terms: D000821:Animal Feed; D000824:Animal Nutritional Physiological Phenomena; D000818:Animals; D001682:Biological Availability; D002417:Cattle / Q000378:metabolism*; D004032:Diet / Q000662:veterinary; D019587:Dietary Supplements; D005260:Female; D008099:Liver / Q000737:chemistry / Q000378:metabolism; D008297:Male; D009753:Nutritive Value; D014801:Vitamin A / Q000032:analysis / Q000493:pharmacokinetics*
chemical_list: D014801:Vitamin A