[Use of endoscopic surgery and combined radiotherapy for inoperable cancer of the esophagus].
A comparative evaluation of the efficacy of combined radiotherapy (112 - group 1) carried out in conjunction with a battery of procedures of endoscopic surgery plus combined radiotherapy (76 - group 2) for inoperable cancer of the esophagus was conducted in 118 patients. Maximum local regression was reported in group 2 (77.6%) as compared with only 33.9% in group 1. Relatively longer relapse-free period (133 days) and lower residual growth incidence (44.6%) were in group 2, too, as compared with 107 days and 63.5% in group 1. Mean survival duration was nearly identical in both groups - ca.15 months. Similarly, survival rates in groups 2 and 1 were: 69.2 and 58.8% (year 1), 22.2 and 22.3% (year 2), and 11.3 and 12.9% (year 3), respectively. It was concluded that combinations of endoscopic surgery and combined radiotherapy for inoperable cancer of the esophagus improved immediate results and reduced the rates of residual tumor incidence. However, no significant differences in mean duration or rates of survival were observed.
Shcherbakov
A M
AM
Kanaev
S V
SV
Shulepov
A V
AV
D003131:Combined Modality Therapy; D018572:Disease-Free Survival; D004724:Endoscopy; D004938:Esophageal Neoplasms / Q000532:radiotherapy* / Q000601:surgery*; D006801:Humans; D012008:Recurrence; D015996:Survival Rate