title: CT features of tuberculous intracranial abscesses in children.
abstract: BACKGROUND
  Intracranial tuberculous (TB) abscesses still cause a diagnostic dilemma on both CT and MRI as they may mimic neoplasms. Recognition of TB abscesses may prompt further imaging and appropriate trial of therapy, and may reduce the need for biopsy.
  
  
  OBJECTIVE
  To report the CT features of eight intracranial TB lesions in children initially diagnosed as neoplasms and eventually treated as TB abscesses.
  
  
  METHODS
  We undertook a 3-year retrospective review of children with an initial CT diagnosis of intracranial neoplasm who were subsequently diagnosed as having TB abscesses.
  
  
  RESULTS
  Eight patients out of 60 with an initial diagnosis of a neoplasm on CT were misdiagnosed and were ultimately determined to have TB abscesses after biopsy or a trial of anti-TB therapy. The most consistent constellation of findings for the lesions were low density (n = 5), ring enhancement (n = 8), cerebral hemisphere location (n = 7), mass effect (n = 6), surrounding oedema (n = 5) and absence of a soft-tissue-density mass (n = 8).
  
  
  CONCLUSIONS
  In endemic regions, intracranial lesions with these appearances on CT should undergo further imaging and possibly a trial of anti-TB therapy before considering biopsy.
authors.affiliation: Department of Radiology, University of Stellenbosch, Tygerberg Hospital, P.O. Box 19063, Tygerberg 7505, South Africa.
authors.forename: Jaco
authors.initials: J
authors.lastname: du Plessis
authors.forename: Savvas
authors.initials: S
authors.lastname: Andronikou
authors.forename: Nicky
authors.initials: N
authors.lastname: Wieselthaler
authors.forename: Salomine
authors.initials: S
authors.lastname: Theron
authors.forename: Reena
authors.initials: R
authors.lastname: George
authors.forename: Ayanda
authors.initials: A
authors.lastname: Mapukata
mesh_terms: D001922:Brain Abscess / Q000000981:diagnostic imaging*; D001932:Brain Neoplasms / Q000000981:diagnostic imaging*; D002648:Child; D002675:Child, Preschool; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D011859:Radiography; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D016862:Tuberculoma, Intracranial / Q000000981:diagnostic imaging*