title: Rulers over randomness: stroma cells guide lymphocyte migration in lymph nodes.
abstract: How is the amoeboid movement of lymphocytes in secondary lymphoid organs orchestrated? In this issue of Immunity, Bajénoff et al. (2006) demonstrate that stromal cell networks serve as guidance structures that direct and limit the migration of B and T cells in lymph nodes.
authors.affiliation: Department of Pathology, Harvard Medical School, Boston, Massachusetts 02115, USA.
authors.forename: Thorsten R
authors.initials: TR
authors.lastname: Mempel
authors.forename: Tobias
authors.initials: T
authors.lastname: Junt
authors.forename: Ulrich H
authors.initials: UH
authors.lastname: von Andrian
mesh_terms: D000818:Animals; D002634:Chemotaxis, Leukocyte / Q000276:immunology*; D006801:Humans; D008198:Lymph Nodes / Q000276:immunology*; D008214:Lymphocytes / Q000276:immunology*; D018448:Models, Immunological; D017154:Stromal Cells / Q000276:immunology*