title: New chemical constituents from the endophyte Streptomyces species LR4612 cultivated on Maytenus hookeri.
abstract: From solid cultures of the biologically important endophyte Streptomyces species LR4612, cultivated on Maytenus hookeri, four new and two known compounds were isolated. The new compounds were identified as (2S*,3S*)-5-amino-3-hydroxy-5-oxopentan-2-yl 3-(formylamino)-2-hydroxybenzoate (1), N-[(3R*,4R*)-3-amino-3,4-dihydro-4-methyl-2,6-dioxo-2H,6H-1,5-benzodioxocin-10-yl]formamide (2), (5beta,6alpha)-6,11-dihydroxyeudesmane (3), and 5-(6,7-dihydroxy-6-methyloctyl)furan-2(5H)-one (4); the known compounds were elucidated as sorbicillin (5) and N-acetyltyramine (6). The structures were established by HR-ESI-MS and in-depth NMR analyses.
authors.affiliation: State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Science, Kunming 650204, Yunnan, PR China.
authors.forename: Pei-Ji
authors.initials: PJ
authors.lastname: Zhao
authors.forename: Guo-Hong
authors.initials: GH
authors.lastname: Li
authors.forename: Yue-Mao
authors.initials: YM
authors.lastname: Shen
mesh_terms: D029755:Maytenus / Q000382:microbiology*; D018517:Plant Roots / Q000382:microbiology; D013302:Streptomyces / Q000737:chemistry* / Q000254:growth & development* / Q000302:isolation & purification