title: The pitfalls in the development of biologic therapy.
authors.forename: Ravinder N
authors.initials: RN
authors.lastname: Maini
authors.forename: Marc
authors.initials: M
authors.lastname: Feldmann
mesh_terms: D000911:Antibodies, Monoclonal / Q000009:adverse effects / Q000627:therapeutic use; D001172:Arthritis, Rheumatoid / Q000188:drug therapy; D001691:Biological Therapy / Q000191:economics / Q000639:trends*; D017277:Drug Approval; D015195:Drug Design; D004345:Drug Industry / Q000191:economics / Q000639:trends*; D006801:Humans; D014409:Tumor Necrosis Factor-alpha / Q000037:antagonists & inhibitors / Q000276:immunology
chemical_list: D000911:Antibodies, Monoclonal; D014409:Tumor Necrosis Factor-alpha