Treatment of Dientamoeba fragilis infection with paromomycin.
Treatment with paromomycin (25-35 mg/kg/d for 7 days) was evaluated prospectively in 15 children with Dientamoeba fragilis infection after 1-month follow-up. At the end of the study, parasitologic effectiveness and clinical improvement were observed in 12/15 (80%) and 13/15 (87%) patients, respectively. Paromomycin appears to be an effective drug for treatment of D. fragilis infection in children.
Vandenberg
Olivier
O
Department of Microbiology, Saint-Pierre University Hospital, Brussels, Belgium.
Souayah
Hichem
H
Mouchet
Françoise
F
Dediste
Anne
A
van Gool
Tom
T
D000293:Adolescent; D000563:Amebicides / Q000627:therapeutic use*; D000818:Animals; D002648:Child; D002675:Child, Preschool; D004029:Dientamoeba / Q000302:isolation & purification*; D004030:Dientamoebiasis / Q000188:drug therapy*; D005260:Female; D005767:Gastrointestinal Diseases / Q000188:drug therapy* / Q000469:parasitology*; D006801:Humans; D007223:Infant; D008297:Male; D010303:Paromomycin / Q000627:therapeutic use*
D000563:Amebicides; D010303:Paromomycin