title: Is mixed-handedness a marker of treatment response in posttraumatic stress disorder?: a pilot study.
abstract: Recent studies suggest that mixed-handedness is a risk factor for posttraumatic stress disorder (PTSD). This study examined whether mixed-handed veterans with combat-related PTSD respond more poorly to psychosocial treatment. Consistency of hand preference was assessed in 150 Vietnam combat veterans with PTSD using the Edinburgh Handedness Inventory (R. C. Oldfield, 1971). Growth modeling analyses using Mplus (L. K. Muthén & B. Muthén, 2002) identified that PTSD veterans with mixed-handedness reported significantly less treatment improvement on the PTSD Checklist (F. W. Weathers, B. T. Litz, D. S. Herman, J. A. Huska, & T. M. Keane, 1993) than did veterans with consistent handedness. These data suggest that mixed-handedness is associated with poorer PTSD treatment response. Several possible explanations for this finding are discussed.
authors.affiliation: Australian Centre for Posttraumatic Mental Health, West Heidelberg, Victoria and University of Melbourne, Melbourne, Australia. dforbes@unimelb.edu.au
authors.forename: David
authors.initials: D
authors.lastname: Forbes
authors.forename: Jessica
authors.initials: J
authors.lastname: Carty
authors.forename: Peter
authors.initials: P
authors.lastname: Elliott
authors.forename: Mark
authors.initials: M
authors.lastname: Creamer
authors.forename: Tony
authors.initials: T
authors.lastname: McHugh
authors.forename: Malcolm
authors.initials: M
authors.lastname: Hopwood
authors.forename: Claude M
authors.initials: CM
authors.lastname: Chemtob
mesh_terms: D003130:Combat Disorders / Q000503:physiopathology* / Q000628:therapy*; D007839:Functional Laterality; D006801:Humans; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D010865:Pilot Projects; D012307:Risk Factors; D013313:Stress Disorders, Post-Traumatic / Q000503:physiopathology* / Q000628:therapy*; D016896:Treatment Outcome; D014481:United States; D014728:Veterans / Q000523:psychology*