title: MR findings of fulminent leukoencephalopathy in EBV-associated hemophagocytic syndrome.
abstract: Various manifestations of brain involvement for patients with virus-associated hemophagocytic syndrome have been reported. Here, we report on the sequential magnetic resonance (MR) findings of acute demyelination of the entire brain with subsequent brain atrophy in a follow-up study of a 25-month- old boy who was admitted with fever and then diagnosed with infectious mononucleosis and EBV-associated hemophagocytic syndrome. We also review other conditions that should be included in the differential diagnosis of this disease.
authors.affiliation: Department of Radiology, Yonsei University College of Medicine, Seoul, Korea.
authors.forename: Jinna
authors.initials: J
authors.lastname: Kim
authors.forename: Seung-Koo
authors.initials: SK
authors.lastname: Lee
authors.forename: Seung Ho
authors.initials: SH
authors.lastname: Joo
authors.forename: Dong Ik
authors.initials: DI
authors.lastname: Kim
authors.forename: Heung Dong
authors.initials: HD
authors.lastname: Kim
mesh_terms: D001927:Brain Diseases / Q000150:complications / Q000473:pathology* / Q000821:virology; D002675:Child, Preschool; D003711:Demyelinating Diseases / Q000150:complications / Q000473:pathology* / Q000821:virology; D003937:Diagnosis, Differential; D020031:Epstein-Barr Virus Infections / Q000150:complications / Q000473:pathology*; D006801:Humans; D051359:Lymphohistiocytosis, Hemophagocytic / Q000209:etiology / Q000473:pathology* / Q000821:virology; D008279:Magnetic Resonance Imaging; D008297:Male