title: ICD-9 codes and surveillance for Clostridium difficile-associated disease.
abstract: We conducted a retrospective cohort study to compare Clostridium difficile-associated disease rates determined by C. difficile-toxin assays and International Classification of Diseases, 9th Revision (ICD-9) codes. The correlation between toxin assay results and ICD-9 codes was good (K = 0.72, p<0.01). The sensitivity of the ICD-9 codes was 78% and the specificity was 99.7%.
authors.affiliation: Washington University in St. Louis-School of Medicine, Saint Louis, Missouri, USA. edubberk@im.wustl.edu
authors.forename: Erik R
authors.initials: ER
authors.lastname: Dubberke
authors.forename: Kimberly A
authors.initials: KA
authors.lastname: Reske
authors.forename: L Clifford
authors.initials: LC
authors.lastname: McDonald
authors.forename: Victoria J
authors.initials: VJ
authors.lastname: Fraser
mesh_terms: D001427:Bacterial Toxins / Q000032:analysis*; D016360:Clostridioides difficile / Q000302:isolation & purification* / Q000378:metabolism; D015331:Cohort Studies; D004761:Enterocolitis, Pseudomembranous / Q000175:diagnosis* / Q000382:microbiology; D005260:Female; D006801:Humans; D038801:International Classification of Diseases; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012680:Sensitivity and Specificity
chemical_list: D001427:Bacterial Toxins