Stereotactic radiosurgery and radiation therapy for spinal tumors.
Spinal tumors constitute 15% of all CNS neoplasms. Radiation therapy can be administered for palliation of pain and spinal cord compression. However, the amount of radiation that can be administered is often limited by the tolerance of the spinal cord, especially in cases where prior radiation therapy has been given. Stereotactic radiosurgery and radiotherapy allow the delivery of a higher dose of radiation to spinal lesions, while limiting the spinal cord dose to below the tolerance level. These are technically demanding procedures and should be performed only when proper equipment and expertise are available. Data on spinal stereotactic radiosurgery and radiotherapy have emerged in recent years. This review summarizes the clinical applications of stereotactic radiosurgery and radiotherapy for spinal tumors.
Lo
Simon S
SS
Department of Radiation Medicine, Ohio State University Medical Center, Columbus, OH 43210, USA. simon.lo@osumc.edu
Chang
Eric L
EL
Yamada
Yoshiya
Y
Sloan
Andrew E
AE
Suh
John H
JH
Mendel
Ehud
E
D004307:Dose-Response Relationship, Radiation; D006801:Humans; D017410:Practice Guidelines as Topic; D010818:Practice Patterns, Physicians'; D011832:Radiation Injuries / Q000209:etiology* / Q000517:prevention & control; D016634:Radiosurgery / Q000009:adverse effects / Q000379:methods* / Q000639:trends*; D011879:Radiotherapy Dosage; D020266:Radiotherapy, Conformal / Q000009:adverse effects / Q000379:methods / Q000639:trends*; D013125:Spinal Neoplasms / Q000532:radiotherapy* / Q000601:surgery*