[Androgen regulates penile erection at the peripheral level].
Androgen has been claimed for so long as a pivotal hormone in regulating male sexual function, acting both at the central and peripheral level. We believe that androgen is indeed the main synchronizer of sexual activity regulating libido and enzymes as nitric oxide synthase (NOS) and phosphodiesterase type 5 ( PDE5) , which are crucial for the erectile process. The main action of androgen is to timely adjust the erectile process as a function manifestation of sexual desire, therefore finalizing erection to sex.
Bai
Wen-jun
WJ
Department of Urology, Peking University People's Hospital, Beijing 100044, China. bai-wj@163.com
Deng
Shi-zhou
SZ
D000728:Androgens / Q000494:pharmacology / Q000502:physiology*; D000818:Animals; D008297:Male; D019001:Nitric Oxide Synthase / Q000378:metabolism; D010410:Penile Erection / Q000187:drug effects / Q000502:physiology*; D010727:Phosphoric Diester Hydrolases / Q000378:metabolism; D051381:Rats
D000728:Androgens; D019001:Nitric Oxide Synthase; D010727:Phosphoric Diester Hydrolases