Ex vivo simulation of drug action: quantification of drug-induced mRNA as a bridge between preclinical and clinical trials.
Mitsuhashi
Masato
M
D000328:Adult; D000818:Animals; D000911:Antibodies, Monoclonal / Q000009:adverse effects*; D017209:Apoptosis; D015415:Biomarkers / Q000097:blood; D018106:CD28 Antigens / Q000276:immunology*; D004353:Drug Evaluation, Preclinical; D006801:Humans; D007249:Inflammation / Q000139:chemically induced / Q000378:metabolism; D051379:Mice; D016133:Polymerase Chain Reaction; D012333:RNA, Messenger / Q000096:biosynthesis* / Q000097:blood
D000911:Antibodies, Monoclonal; D015415:Biomarkers; D018106:CD28 Antigens; D012333:RNA, Messenger