title: Non-heart-beating kidney transplantation: 6-year outcomes.
abstract: Non-heart-beating donor kidneys (NHBD) are being used to increase the donor pool due to the scarcity of cadaveric heart beating donors (HBD). We evaluated the long-term outcomes of renal transplantation using NHBD kidneys, comparing the first 100 NHBD kidneys transplanted at our facility to the next consecutive cadaveric HBD kidneys for graft survival, recipient survival, and quality of graft function. Recipient survival (P = .22) and graft survival (P = .19) at 6 years did not differ between recipients of NHBD (83%, 80%) and HBD (89%, 87%) kidneys. Quality of graft function using the mean glomular filtration rates were significantly lower in the NHBD group up to 3 months following discharge (41 +/- 2 vs 47 +/- 2, P = .007) but were then comparable up to 6 years following transplantation (43 +/- 5 vs 46 +/- 4, P = .55).
authors.affiliation: Regional Liver/Renal Transplant Unit, Freeman Hospital, Newcastle upon Tyne, United Kingdom. aliu_oladipupo@yahoo.com
authors.forename: A O
authors.initials: AO
authors.lastname: Sanni
authors.forename: C H
authors.initials: CH
authors.lastname: Wilson
authors.forename: H
authors.initials: H
authors.lastname: Wyrley-Birch
authors.forename: D
authors.initials: D
authors.lastname: Vijayanand
authors.forename: A
authors.initials: A
authors.lastname: Navarro
authors.forename: M A
authors.initials: MA
authors.lastname: Gok
authors.forename: S
authors.initials: S
authors.lastname: Sohrabi
authors.forename: B
authors.initials: B
authors.lastname: Jaques
authors.forename: D
authors.initials: D
authors.lastname: Rix
authors.forename: N
authors.initials: N
authors.lastname: Soomro
authors.forename: D
authors.initials: D
authors.lastname: Manas
authors.forename: D
authors.initials: D
authors.lastname: Talbot
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D005500:Follow-Up Studies; D006323:Heart Arrest; D006650:Histocompatibility Testing; D006801:Humans; D016030:Kidney Transplantation / Q000276:immunology / Q000502:physiology*; D008297:Male; D008875:Middle Aged; D018579:Patient Selection; D010477:Perfusion / Q000379:methods; D012189:Retrospective Studies; D013997:Time Factors; D014019:Tissue Donors / Q000706:statistics & numerical data*; D016896:Treatment Outcome