title: Tolerance to opiate reward: role of midbrain IRS2-Akt pathway.
authors.forename: Brandon K
authors.initials: BK
authors.lastname: Harvey
authors.forename: Bruce T
authors.initials: BT
authors.lastname: Hope
authors.forename: Yavin
authors.initials: Y
authors.lastname: Shaham
mesh_terms: D000818:Animals; D004361:Drug Tolerance; D055504:Insulin Receptor Substrate Proteins; D047908:Intracellular Signaling Peptides and Proteins / Q000502:physiology*; D009474:Neurons / Q000502:physiology; D051058:Oncogene Protein v-akt / Q000502:physiology*; D010750:Phosphoproteins / Q000502:physiology*; D051381:Rats; D012201:Reward; D015398:Signal Transduction / Q000502:physiology; D017557:Ventral Tegmental Area / Q000166:cytology
chemical_list: D055504:Insulin Receptor Substrate Proteins; D047908:Intracellular Signaling Peptides and Proteins; C526299:Irs2 protein, rat; D010750:Phosphoproteins; D051058:Oncogene Protein v-akt