vCJD and blood transfusion in the United Kingdom.
A study was set up in the UK in 1997 to examine whether there is any evidence that variant Creutzfeldt-Jakob disease (vCJD) is transmitted by blood transfusion. To date, the study has identified three probable cases of vCJD transmission by blood transfusion, including two clinical cases and one pre- (or sub-) clinical case.
Hewitt
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National Blood Service, 75, Cranmer Terrace, London SW17 ORB, UK. patricia.hewitt@nbs.nhs.uk
D000328:Adult; D000368:Aged; D000818:Animals; D001803:Blood Transfusion / Q000592:standards*; D002417:Cattle; D007562:Creutzfeldt-Jakob Syndrome / Q000453:epidemiology / Q000401:mortality / Q000517:prevention & control / Q000635:transmission*; D004195:Disease Models, Animal; D016643:Encephalopathy, Bovine Spongiform / Q000453:epidemiology; D006801:Humans; D008875:Middle Aged; D012307:Risk Factors; D012608:Scrapie / Q000453:epidemiology; D016019:Survival Analysis; D065227:Transfusion Reaction; D006113:United Kingdom / Q000453:epidemiology