Antimicrobial activity of some medicinal barks used in Peruvian Amazon.
The aim of this study was to evaluate the antimicrobial activity of six barks traditionally used in Callería District (Ucayali Department, Peru) for treating conditions likely to be associated with microorganisms. Ethanol extracts of stem barks of Abuta grandifolia (Menispermaceae), Dipteryx micrantha (Leguminosae), Cordia alliodora (Boraginaceae), Naucleopsis glabra (Moraceae), Pterocarpus rohrii (Leguminosae), and root bark of Maytenus macrocarpa (Celastraceae) were tested against nine bacteria and one yeast using the broth microdilution method. All plants possessed significant antimicrobial effect, however, the extract of Naucleopsis glabra exhibited the strongest activity against Gram-positive bacteria (MICs ranging from 62.5 to 125 microg/ml), while the broadest spectrum of action was shown by the extract of Maytenus macrocarpa, which inhibited all the strains tested with MICs ranging from 125 to 250 microg/ml.
Kloucek
P
P
Department of Crop Production, Faculty of Agrobiology, Food and Natural Resources, Czech University of Agriculture Prague, Kamycka 129, 165 21 Prague 6-Suchdol, Czech Republic.
Svobodova
B
B
Polesny
Z
Z
Langrova
I
I
Smrcek
S
S
Kokoska
L
L
D000900:Anti-Bacterial Agents / Q000494:pharmacology* / Q000627:therapeutic use; D004353:Drug Evaluation, Preclinical; D005843:Geography; D006094:Gram-Positive Bacteria / Q000187:drug effects*; D006801:Humans; D008519:Medicine, Traditional; D008826:Microbial Sensitivity Tests; D010568:Peru; D008517:Phytotherapy; D024301:Plant Bark / Q000737:chemistry*; D018517:Plant Roots / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry* / Q000145:classification
D000900:Anti-Bacterial Agents