title: Structure and binding properties of water-soluble cavitands and capsules.
abstract: Synthetic receptors are modern tools for investigations into the forces involved in recognition. A widely exploited class of receptors are the resorcin[4]arene-based cavitands and capsules. This critical review (71 references) describes the evolution of water-soluble versions of these structures, along with insights the resulting host-ndash complexes have provided with regard to complexation driving forces in water. An emphasis has been placed on the influence of host structure on guest affinity and dynamics.
authors.affiliation: The Skaggs Institute for Chemical Biology, Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, MB26, La Jolla, CA 92037, USA.
authors.forename: Shannon M
authors.initials: SM
authors.lastname: Biros
authors.forename: Julius
authors.initials: J
authors.lastname: Rebek
mesh_terms: D004988:Ethers, Cyclic / Q000737:chemistry*; D015394:Molecular Structure; D012995:Solubility; D014867:Water / Q000737:chemistry*
chemical_list: D004988:Ethers, Cyclic; D014867:Water