Factor V Leiden: an overview.
This paper provides an update and an overview of factor V Leiden, an inherited condition, which predisposes affected individuals to thrombosis. Factor V Leiden occurs due to a single point mutation on chromosome one. Tests for factor V Leiden include screening for activated protein C (APC) resistance, and if positive, testing for the Factor V Leiden mutation.
Shaw
Donna M
DM
Department of Medical and Research Technology, University of Maryland School of Medicine, Baltimore, USA. dshaw002@att.net
D005165:Factor V / Q000235:genetics*; D020022:Genetic Predisposition to Disease; D006801:Humans; D019851:Thrombophilia / Q000150:complications / Q000188:drug therapy / Q000235:genetics*; D013927:Thrombosis / Q000209:etiology* / Q000235:genetics
C095381:factor V Leiden; D005165:Factor V