Neonatal anemia and hydrops fetalis after maternal mycophenolate mofetil use.
After admitting a patient to our Neonatal Intensive Care with a severe anemia and an ear malformation, we ruled out any other cause than maternal medication use. Knowing she used mycophenolate mofetil during pregnancy, we looked for related articles. Two articles were found describing ear malformations, but no article was ever written about anemia caused by this medication. Consulting the international registers of drug effects through the National Institute for Public Health and the Environment, we found out that the anemia was never seen or reported before.
Tjeertes
I F A
IF
Department of Neonatology, Isala Klinieken, Zwolle, The Netherlands.
Bastiaans
D E T
DE
van Ganzewinkel
C J L M
CJ
Zegers
S H J
SH
D000014:Abnormalities, Drug-Induced / Q000175:diagnosis / Q000209:etiology*; D000328:Adult; D000751:Anemia, Neonatal / Q000139:chemically induced*; D004431:Ear, External / Q000002:abnormalities*; D005260:Female; D006801:Humans; D015160:Hydrops Fetalis / Q000139:chemically induced*; D007166:Immunosuppressive Agents / Q000009:adverse effects* / Q000627:therapeutic use; D007231:Infant, Newborn; D008297:Male; D009173:Mycophenolic Acid / Q000009:adverse effects / Q000031:analogs & derivatives* / Q000627:therapeutic use; D011247:Pregnancy; D011248:Pregnancy Complications / Q000188:drug therapy
D007166:Immunosuppressive Agents; D009173:Mycophenolic Acid