[Relative biological effectiveness of accelerated heavy ions and fast neutrons estimated from frequency of aberration mytoses in the retinal epithelium].
Analyzed was the literature and authors' experimental data concerning lesion and recovery of epithelium cells of mice retina immediately and long after irradiation at different sources including single and partly fractionated irradiation by gamma- and X-rays, accelerated protons, helium, carbon and boron ions, and fast neutrons of the reactor range in a large spectrum of doses and LET. Reviewed are some new techniques of determining the RBE coefficient for these types of radiation; large values of the RBE coefficients for accelerated ions and neutrons (5-10 times higher than RBE coefficients calculated for the next day following irradiation) are a result of integration into calculation of the available data about the delayed disorders in retinal epithelium cell regeneration.
Vorozhtsova
S V
SV
Shafirkin
A V
AV
Fedorenko
B S
BS
D000818:Animals; D001895:Boron; D002244:Carbon; D004848:Epithelium / Q000502:physiology / Q000528:radiation effects*; D005214:Fast Neutrons / Q000009:adverse effects*; D020450:Heavy Ions / Q000009:adverse effects*; D006371:Helium; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D008938:Mitosis / Q000528:radiation effects*; D011379:Prognosis; D012038:Regeneration / Q000528:radiation effects*; D012160:Retina / Q000502:physiology / Q000528:radiation effects*
D006371:Helium; D002244:Carbon; D001895:Boron