Sarcoidosis presenting as an osteolytic skull lesion: a case report and review of literature on skull sarcoidosis.
Bone sarcoidosis of the skull is an infrequent presentation of sarcoidosis. We describe a 51-year-old man who consulted due to inflammatory-appearing nodulation in the right supraorbital region. Images showed a solitary osteolytic lesion extending to soft tissues with increased scintigraphic uptake. The anatomopathological study revealed the presence of non-caseating epithelioid granulomas, compatible with sarcoidosis. Steroid treatment led to a marked remission of the lesion, without evidence of relapse during a follow-up period of 1 year. The literature dealing with skull sarcoidosis is reviewed.
Fernández-Ruiz
Mario
M
Department of Internal Medicine, Hospital Universitario 12 de Octubre, Universidad Complutense de Madrid, Avenida de Córdoba, s/n, 28041, Madrid, Spain. mario_fdezruiz@yahoo.es
Guerra-Vales
Juan-Manuel
JM
Castelbón-Fernández
Francisco-Javier
FJ
Llenas-García
Jara
J
Rodríguez-Peralto
Jose-Luis
JL
López-Lancho
Roberto
R
Redondo-Marcos
Irene
I
D001706:Biopsy; D006259:Craniocerebral Trauma / Q000175:diagnosis*; D003937:Diagnosis, Differential; D005710:Gallium Radioisotopes / Q000627:therapeutic use; D006099:Granuloma / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D010014:Osteolysis / Q000175:diagnosis*; D012507:Sarcoidosis / Q000175:diagnosis*; D012886:Skull / Q000473:pathology*; D013256:Steroids / Q000627:therapeutic use; D014057:Tomography, X-Ray Computed / Q000379:methods; D016896:Treatment Outcome
D005710:Gallium Radioisotopes; D013256:Steroids