title: 25-gauge vs 20-gauge system for pars plana vitrectomy: a prospective randomised clinical trial.
abstract: OBJECTIVE
  To compare 25-gauge vs 20-gauge system for pars plana vitrectomy in a prospective, randomised, controlled clinical trial.
  
  
  METHODS
  Three-port pars plana vitrectomy was performed in 60 patients belonging to 2 groups. Evaluations were performed preoperatively, intraoperatively, during the first three postoperative days, at 1 week, and at 1 and 3 months. The main outcome measure was time for surgery, divided into duration of wound opening, vitrectomy, retinal manipulation and wound closure.
  
  
  RESULTS
  The total duration of surgery showed no significant difference between the groups (p = 0.67). The 25-gauge group showed significantly shorter duration of wound opening (p<0.001) and wound closure (p<0.001). In contrast, the vitrectomy duration was significantly longer in the 25-gauge group (p<0.001). Conjunctival injection and subjective postoperative pain showed significantly lower irritation in the 25-gauge group (p<0.001 for both).
  
  
  CONCLUSIONS
  The 25-gauge vitrectomy system offered significantly improved patient comfort during the first postoperative week. The smaller surgical openings facilitated wound healing and minimised pain. Duration of surgery was comparable between the two systems-the shorter time needed for wound opening and closure in the 25-gauge group being equalised by the longer vitrectomy duration. Intraoperative as well as retinal manipulation and illumination caused more surgical difficulties using the 25-gauge system.
authors.affiliation: Department of Ophthalmology, Rudolph Foundation Clinic, Vienna, Austria.
authors.forename: Lukas
authors.initials: L
authors.lastname: Kellner
authors.forename: Barbara
authors.initials: B
authors.lastname: Wimpissinger
authors.forename: Ulrike
authors.initials: U
authors.lastname: Stolba
authors.forename: Werner
authors.initials: W
authors.lastname: Brannath
authors.forename: Susanne
authors.initials: S
authors.lastname: Binder
mesh_terms: D019773:Epiretinal Membrane / Q000601:surgery; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007429:Intraocular Pressure; D007432:Intraoperative Period; D008297:Male; D010149:Postoperative Pain; D011446:Prospective Studies; D012164:Retinal Diseases / Q000601:surgery*; D012167:Retinal Perforations / Q000601:surgery; D016896:Treatment Outcome; D014792:Visual Acuity; D014821:Vitrectomy / Q000009:adverse effects / Q000295:instrumentation* / Q000379:methods; D014945:Wound Healing