title: Sarcoidosis presenting as an osteolytic skull lesion: a case report and review of literature on skull sarcoidosis.
abstract: Bone sarcoidosis of the skull is an infrequent presentation of sarcoidosis. We describe a 51-year-old man who consulted due to inflammatory-appearing nodulation in the right supraorbital region. Images showed a solitary osteolytic lesion extending to soft tissues with increased scintigraphic uptake. The anatomopathological study revealed the presence of non-caseating epithelioid granulomas, compatible with sarcoidosis. Steroid treatment led to a marked remission of the lesion, without evidence of relapse during a follow-up period of 1 year. The literature dealing with skull sarcoidosis is reviewed.
authors.affiliation: Department of Internal Medicine, Hospital Universitario 12 de Octubre, Universidad Complutense de Madrid, Avenida de Córdoba, s/n, 28041, Madrid, Spain. mario_fdezruiz@yahoo.es
authors.forename: Mario
authors.initials: M
authors.lastname: Fernández-Ruiz
authors.forename: Juan-Manuel
authors.initials: JM
authors.lastname: Guerra-Vales
authors.forename: Francisco-Javier
authors.initials: FJ
authors.lastname: Castelbón-Fernández
authors.forename: Jara
authors.initials: J
authors.lastname: Llenas-García
authors.forename: Jose-Luis
authors.initials: JL
authors.lastname: Rodríguez-Peralto
authors.forename: Roberto
authors.initials: R
authors.lastname: López-Lancho
authors.forename: Irene
authors.initials: I
authors.lastname: Redondo-Marcos
mesh_terms: D001706:Biopsy; D006259:Craniocerebral Trauma / Q000175:diagnosis*; D003937:Diagnosis, Differential; D005710:Gallium Radioisotopes / Q000627:therapeutic use; D006099:Granuloma / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D010014:Osteolysis / Q000175:diagnosis*; D012507:Sarcoidosis / Q000175:diagnosis*; D012886:Skull / Q000473:pathology*; D013256:Steroids / Q000627:therapeutic use; D014057:Tomography, X-Ray Computed / Q000379:methods; D016896:Treatment Outcome
chemical_list: D005710:Gallium Radioisotopes; D013256:Steroids