title: Trends in herpes simplex virus type 1 and 2 infections among patients diagnosed with genital herpes in a Finnish sexually transmitted disease clinic, 1994-2002.
abstract: OBJECTIVE
  The objective of this study was to analyze the proportion of herpes simplex virus types 1 and 2 (HSV-1 and -2) in genital infections during a 9-year period (1994-2002) in a Finnish sexually transmitted disease (STD) clinic population.
  
  
  METHODS
  We analyzed prospectively the proportion of HSV-1- or -2-positive culture samples from our STD clinic patients with genital herpes during years 1994-2002 and compared the proportions of HSV-1 and HSV-2 findings with the age and gender of the patients.
  
  
  RESULTS
  The proportion of HSV-1 infections increased from 18.7% (39 of 209) in 1994-1996 to 25.9% (52 of 201) in 2000-2002 (P = 0.032). Female patients with genital herpes and laboratory isolation of HSV-1 were 35.9% of the cohort from 1994-1996 and 67.3% of the cohort from 2000-2002. The mean age of male patients with HSV-1 decreased from 29.3 years in 1994-1996 to 24.1 years in 2000-2002 (P = 0.023).
  
  
  CONCLUSIONS
  An increase in the proportion of genital infections caused by HSV-1 was found. The increase was mainly the result of the increase in the number of female patients with HSV-1. Male patients acquire genital HSV-1 infection at a younger age than 10 years ago.
authors.affiliation: Department of Dermatology, University Central Hospital, Turku, Finland. outi.kortekangas-savolainen@tyks.fi
authors.forename: Outi
authors.initials: O
authors.lastname: Kortekangas-Savolainen
authors.forename: Tytti
authors.initials: T
authors.lastname: Vuorinen
mesh_terms: D000328:Adult; D017677:Age Distribution; D000554:Ambulatory Care Facilities; D005260:Female; D005387:Finland / Q000453:epidemiology; D015658:HIV Infections / Q000150:complications / Q000453:epidemiology*; D015497:HIV-1; D015498:HIV-2; D006558:Herpes Genitalis / Q000150:complications / Q000453:epidemiology*; D006801:Humans; D008297:Male; D011446:Prospective Studies; D017678:Sex Distribution