title: Refractive outcomes after primary intraocular lens implantation in infants.
abstract: BACKGROUND
  Intraocular lens (IOL) implantation is becoming increasingly accepted as a primary procedure in infants.
  
  
  OBJECTIVE
  To evaluate the accuracy of IOL power calculation, the rate of myopic shift and the refractive outcome after primary IOL implantation in infants aged <12 months at the time of cataract surgery.
  
  
  METHODS
  A retrospective case review of 25 patients (8 with bilateral cataracts and 17 with unilateral cataracts) who underwent cataract surgery with primary IOL implantation at <12 months of age. Outcomes measured were actual early postoperative refraction, lens power calculation error, myopic shift and refractive outcome.
  
  
  RESULTS
  In 83% of cases, actual postoperative refraction was within 2 dioptres (D) of the target refraction. Lens power calculation error did not depend on axial length, age at surgery or target refraction. Mean (SD) myopic shift was 5.43 (3.7) D in the first 12 months after surgery, but was significantly greater when surgery was performed at <10 weeks of age.
  
  
  CONCLUSIONS
  This study demonstrates that IOL power can be calculated with reasonable accuracy in infants using current formulas. Factors such as age at the time of surgery, axial length, whether surgery is unilateral or bilateral, and the presence of systemic pathologies do not seem to influence the accuracy of lens power calculation or myopic shift up to 36 months of age.
authors.affiliation: Manchester Royal Eye Hospital, Oxford Road, Manchester M13 9WH, UK. jane.ashworth@CMMC.nhs.uk
authors.forename: J L
authors.initials: JL
authors.lastname: Ashworth
authors.forename: A P
authors.initials: AP
authors.lastname: Maino
authors.forename: S
authors.initials: S
authors.lastname: Biswas
authors.forename: I C
authors.initials: IC
authors.lastname: Lloyd
mesh_terms: D000367:Age Factors; D002386:Cataract / Q000503:physiopathology*; D002387:Cataract Extraction; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D019654:Lens Implantation, Intraocular / Q000592:standards*; D007910:Lenses, Intraocular / Q000592:standards*; D008297:Male; D009216:Myopia / Q000209:etiology / Q000503:physiopathology; D012029:Refraction, Ocular / Q000502:physiology*; D012030:Refractive Errors / Q000209:etiology / Q000503:physiopathology; D012189:Retrospective Studies