title: Preliminary study: color map of hepatocellular carcinoma using dynamic contrast-enhanced 256-detector row CT.
abstract: To distinguish hepatocellular carcinoma (HCC) from normal liver tissue, a color map was made by dynamic contrast-enhanced 256-detector row CT developed at our institute. Dynamic enhanced CT of the liver of three patients with HCC was studied. The CT has 912 (transverse) x 256 (cranio-caudal) elements, each measuring approximately 0.5 mm x 0.5mm at the center of rotation. Scanning for 10 s (1.0 s/rotation) was started 30 s after intravenous injection of contrast medium. The reconstruction increment was 0.62 mm with a time interval of 0.1s and a matrix size of 512 x 512 x 256. Color maps were generated to show the gradient of the regression line of the time-density change. Due to volume acquisition, the 3D color map can be created using continuous 10-s scanning. The densities of the HCC and liver were decreased and increased during scanning, respectively. The HCC was detected clearly in the color map as a downward-sloping region. Dynamic enhanced 256-detector row CT could be useful for detecting malignant tumors in the liver with a short scan time.
authors.affiliation: Department of Medical Physics, National Institute of Radiological Sciences, Chiba 263-8555, Japan.
authors.forename: Shinichiro
authors.initials: S
authors.lastname: Mori
authors.forename: Takayuki
authors.initials: T
authors.lastname: Obata
authors.forename: Hirotoshi
authors.initials: H
authors.lastname: Kato
authors.forename: Riwa
authors.initials: R
authors.lastname: Kishimoto
authors.forename: Susumu
authors.initials: S
authors.lastname: Kandatsu
authors.forename: Shuji
authors.initials: S
authors.lastname: Tanada
authors.forename: Masahiro
authors.initials: M
authors.lastname: Endo
mesh_terms: D000368:Aged; D006528:Carcinoma, Hepatocellular / Q000000981:diagnostic imaging*; D003287:Contrast Media; D006801:Humans; D007089:Image Enhancement; D007275:Injections, Intravenous; D008113:Liver Neoplasms / Q000000981:diagnostic imaging*; D008297:Male; D008875:Middle Aged; D012107:Research Design; D014057:Tomography, X-Ray Computed / Q000379:methods*
chemical_list: D003287:Contrast Media