title: New photoproducts from irradiation of NADH with near-UV light.
abstract: Adenosine 5'-diphosphoribose (ADPR) and a second compound, which may be nicotinamide, are the newly discovered photoproducts resulting from irradiation of beta-nicotinamide adenine dinucleotide (beta-NADH) in the wavelength range of 300-400 nm under oxygen-poor conditions. Both products emerge there even exclusively, whereas, at higher oxygen concentrations, the oxidized form of nicotinamide adenine dinucleotide (NAD+) is additionally formed, although still as a minor product. The development of ADPR and NAD+ is clearly oxygen-dependent, while, for the formation of the second photoproduct, small quantities of oxygen appear to be sufficient.
authors.affiliation: Max-Planck-Institut für Bioanorganische Chemie (former MPI für Strahlenchemie), P.O. Box 101365, D-45413 Mülheim an der Ruhr. vitiniusu@yahoo.com
authors.forename: Ute
authors.initials: U
authors.lastname: Vitinius
authors.forename: Kurt
authors.initials: K
authors.lastname: Schaffner
authors.forename: Martin
authors.initials: M
authors.lastname: Demuth
authors.forename: Marija
authors.initials: M
authors.lastname: Heibel
authors.forename: Horst
authors.initials: H
authors.lastname: Selbach
mesh_terms: D009243:NAD / Q000032:analysis / Q000737:chemistry* / Q000528:radiation effects*; D010777:Photochemistry; D014466:Ultraviolet Rays
chemical_list: D009243:NAD