Remote modulation of amine basicity by a phenylsulfone and a phenylthio group.
Martin
Rainer E
RE
Pharmaceuticals Division, Discovery Chemistry, F. Hoffmann-La Roche Ltd, 4070 Basel, Switzerland.
Plancq
Baptiste
B
Gavelle
Olivier
O
Wagner
Björn
B
Fischer
Holger
H
Bendels
Stefanie
S
Müller
Klaus
K
D000588:Amines / Q000737:chemistry*; D013438:Sulfhydryl Compounds / Q000737:chemistry / Q000494:pharmacology*; D013450:Sulfones / Q000737:chemistry / Q000494:pharmacology*
D000588:Amines; D013438:Sulfhydryl Compounds; D013450:Sulfones