Enantiospecific syntheses of C(5)-functionalized precursors of artemisinin derivatives.
Enantiomerically pure compounds as precursors for the synthesis of hydroxylated derivatives of artemisinin/arteether have been prepared from (+)-(S)-carvone and (+)-car-2-ene.
Cravero
Raquel M
RM
Instituto de Química Orgánica de Síntesis, Departamento de Química Orgánica, Facultad de Ciencias Bioquímicas y Farmacéuticas, Universidad Nacional de Rosario, Suipacha 531, S2002LRK Rosario, Argentina.
Labadie
Guillermo R
GR
Gonzalez Sierra
Manuel
M
Mc Chesney
James D
JD
D037621:Artemisinins / Q000138:chemical synthesis*; D012717:Sesquiterpenes / Q000138:chemical synthesis*; D013237:Stereoisomerism
D037621:Artemisinins; D012717:Sesquiterpenes; C031327:artemisinin