title: Optical coherence tomography findings in acute retinal pigment epitheliitis.
abstract: OBJECTIVE
  To report the optical coherence tomography (OCT) findings in three patients with acute retinal pigment epitheliitis (ARPE).
  
  
  METHODS
  Retrospective, observational case series.
  
  
  METHODS
  The charts of three patients with ARPE were reviewed. Approval from the Institutional Review Board was obtained. Fundus photographs, fluorescein angiograms, and OCT findings were examined.
  
  
  RESULTS
  Three healthy, young patients presented with acute unilateral blurred vision. Ophthalmoscopy revealed fine pigment stippling surrounded by haloes of hypopigmentation. Fluorescein angiography demonstrated transmission hyperfluorescence. OCT showed abnormal foveal hyperreflectivity involving the outer nuclear layer and photoreceptors in all cases. Disruption of the retinal pigment epithelium (RPE) was seen in two cases. With resolution, the abnormal hyperreflectivity decreased in thickness.
  
  
  CONCLUSIONS
  OCT confirms the involvement of the outer neurosensory retina in acute retinal pigment epitheliitis. RPE involvement may be a secondary post-inflammatory response, because one case did not have significant disruption of the RPE.
authors.affiliation: Retina Service, Wills Eye Hospital, Thomas Jefferson University, 840 Walnut Street, Philadelphia, PA 19107, USA.
authors.forename: Jason
authors.initials: J
authors.lastname: Hsu
authors.forename: Mitchell S
authors.initials: MS
authors.lastname: Fineman
authors.forename: Richard S
authors.initials: RS
authors.lastname: Kaiser
mesh_terms: D000208:Acute Disease; D000328:Adult; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D008297:Male; D009887:Ophthalmoscopy; D010781:Photography; D010857:Pigment Epithelium of Eye / Q000473:pathology*; D012164:Retinal Diseases / Q000175:diagnosis*; D012189:Retrospective Studies; D041623:Tomography, Optical Coherence / Q000379:methods*