title: Testicular seminoma occurring 8 years after treatment of a metastatic extragonadal germ cell tumor.
abstract: A 30-year-old man was admitted with a chief complaint of left-sided scrotal enlargement, and was diagnosed as having testicular seminoma after orchiectomy. Eight years earlier, he had been treated with chemotherapy for an extragonadal germ cell tumor, without orchiectomy, leading to complete remission. His histological diagnosis at that time was a germ cell tumor, composed of choriocarcinoma and embryonal carcinoma. He was followed up without testicular biopsy. Routine pretreatment testicular biopsy in patients with extragonadal germ cell tumor is controversial, but regular long-term follow up and information on the risk of developing a metachronous testicular tumor are needed after treatment of extragonadal germ cell tumors, even when there seems to be a partial or complete clinical response.
authors.affiliation: Department of Nephro-urology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan. ryo@med.nagoya-cu.ac.jp
authors.forename: Ryosuke
authors.initials: R
authors.lastname: Ando
authors.forename: Takahiro
authors.initials: T
authors.lastname: Yasui
authors.forename: Keiichi
authors.initials: K
authors.lastname: Tozawa
authors.forename: Shoichi
authors.initials: S
authors.lastname: Sasaki
authors.forename: Yutaro
authors.initials: Y
authors.lastname: Hayashi
authors.forename: Kenjiro
authors.initials: K
authors.lastname: Kohri
mesh_terms: D000328:Adult; D006801:Humans; D008297:Male; D009373:Neoplasms, Germ Cell and Embryonal / Q000188:drug therapy*; D016609:Neoplasms, Second Primary / Q000175:diagnosis*; D018239:Seminoma / Q000175:diagnosis*; D013736:Testicular Neoplasms / Q000175:diagnosis* / Q000188:drug therapy*