title: Electroosmotic flow patterning using microfluidic delay loops.
abstract: A theoretical and experimental investigation of alternating electroosmotic flow patterns by means of specially designed delay loops is presented. Using elementary methods of compact network modeling and detailed FEM simulations the flow behavior and, in particular, the rearrangement of sample plugs is modeled. The proposed designs rely on flow splitting in combination with electroosmotic delay loops leading to a runtime difference or phase shift between two sub-streams. Due to this phase shift, a new fluid interface is generated at the merging point. The approach is experimentally validated by injection of a Rhodamine 6G solution into an aqueous sodium tetraborate buffer.
authors.affiliation: Institut für Mikrotechnik Mainz GmbH, Carl-Zeiss-Str. 18-20, Mainz, 55129, Germany. schoenfeld@imm-mainz.de
authors.forename: F
authors.initials: F
authors.lastname: Schönfeld
authors.forename: S
authors.initials: S
authors.lastname: Hardt
authors.forename: M
authors.initials: M
authors.lastname: Böhm
authors.forename: R J
authors.initials: RJ
authors.lastname: Püschl
authors.forename: M
authors.initials: M
authors.lastname: Walder
authors.forename: B
authors.initials: B
authors.lastname: Wenclawiak
mesh_terms: D001881:Borates / Q000737:chemistry; D003198:Computer Simulation; D004563:Electrochemistry; D019075:Electrophoresis, Capillary / Q000295:instrumentation / Q000379:methods; D004867:Equipment Design; D046210:Microfluidic Analytical Techniques / Q000295:instrumentation* / Q000379:methods*; D009995:Osmosis; D012680:Sensitivity and Specificity
chemical_list: D001881:Borates; C010634:sodium borate