[Autochthonous hepatitis E in France].
Hepatitis E must no longer be considered simply as an exotic disease occasionally imported from developing countries. Autochthonous hepatitis E exists in France. In spite of certain difficulties and limits, biological markers of hepatitis E have to be included in algorithms for etiological diagnosis of acute hepatitis, even if the patient has not recently traveled abroad. Based on a recombinant protein of the viral capsid, more sensitive serological assays should soon be available. The potential severity of hepatitis E, especially during pregnancy, calls for a national surveillance program, including evaluation of the animal reservoir and the risk associated with drinking water and food.
Buisson
Yves
Y
Institut de Mèdecine tropicale du Service de santé des armées, B.P. 46, 13998 Marseile Armées.
Nicand
Elisabeth
E
D000328:Adult; D000465:Algorithms; D000818:Animals; D004197:Disease Reservoirs; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D005602:France / Q000453:epidemiology; D005838:Genotype; D006508:Hepatitis Antibodies / Q000032:analysis; D016751:Hepatitis E / Q000175:diagnosis / Q000453:epidemiology* / Q000517:prevention & control / Q000821:virology; D016752:Hepatitis E virus / Q000235:genetics / Q000276:immunology; D006801:Humans; D008297:Male; D016133:Polymerase Chain Reaction; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000175:diagnosis; D015995:Prevalence; D012367:RNA, Viral / Q000032:analysis; D020133:Reverse Transcriptase Polymerase Chain Reaction; D012307:Risk Factors; D015047:Zoonoses
D006508:Hepatitis Antibodies; D012367:RNA, Viral