title: Pharmacoeconomic studies in Italy: a critical review of the literature.
abstract: To assess the state of pharmacoeconomics in Italy we reviewed all the original studies published by Italian authors in national and international journals from January 1994 to December 2003. We selected 70 articles and broadly assessed 92 economic evaluations (EEs) since some articles contained multiple analyses. We adopted common analysis criteria to allow methodological comparison of the studies. The variables investigated can be grouped into three categories: general methods, costs, and consequences. To further assess the quality of the EEs, we decided to rank them according to criteria of both clinical and economic good practice. Then, to complete our critical evaluation, we analysed whether sponsorship might have somehow affected the results. Our analysis seems to support the widespread scepticism of the Italian NHS decision-makers towards pharmacoeconomic studies, whose results seem to be biased by flawed methods and sponsors' interference with results.
authors.affiliation: CESAV, Center for Health Economics, Mario Negri Institute for Pharmacological Research, Villa Camozzi -Via Camozzi, 3, 24020, Ranica (Bg), Italy.
authors.forename: D
authors.initials: D
authors.lastname: Cornago
authors.forename: L
authors.initials: L
authors.lastname: Li Bassi
authors.forename: P
authors.initials: P
authors.lastname: De Compadri
authors.forename: L
authors.initials: L
authors.lastname: Garattini
mesh_terms: D017850:Economics, Pharmaceutical; D006801:Humans; D007558:Italy