title: Production of dihydroisocoumarins in Fusarium verticillioides by swapping ketosynthase domain of the fungal iterative polyketide synthase Fum1p with that of lovastatin diketide synthase.
authors.affiliation: Department of Chemistry, University of Nebraska--Lincoln, Lincoln, Nebraska 68588, USA.
authors.forename: Xiangcheng
authors.initials: X
authors.lastname: Zhu
authors.forename: Fengan
authors.initials: F
authors.lastname: Yu
authors.forename: Xing-Cong
authors.initials: XC
authors.lastname: Li
authors.forename: Liangcheng
authors.initials: L
authors.lastname: Du
mesh_terms: D005656:Fungal Proteins / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D005670:Fusarium / Q000201:enzymology* / Q000235:genetics; D049934:Isocoumarins / Q000378:metabolism*; D008148:Lovastatin / Q000378:metabolism; D048630:Polyketide Synthases / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D015202:Protein Engineering; D017434:Protein Structure, Tertiary / Q000235:genetics; D011993:Recombinant Fusion Proteins / Q000235:genetics / Q000378:metabolism*
chemical_list: D005656:Fungal Proteins; D049934:Isocoumarins; D011993:Recombinant Fusion Proteins; D048630:Polyketide Synthases; D008148:Lovastatin