title: Neurological symptoms in type A aortic dissections.
abstract: OBJECTIVE
  Aortic dissection typically presents with severe chest or back pain. Neurological symptoms may occur because of occlusion of supplying vessels or general hypotension. Especially in pain-free dissections diagnosis can be difficult and delayed. The purpose of this study is to analyze the association between type A aortic dissection and neurological symptoms.
  
  
  METHODS
  Clinical records of 102 consecutive patients with aortic dissection (63% male, median age 58 years) over 7.5 years were analyzed for medical history, preoperative clinical characteristics, treatment and outcome with main emphasis on neurological symptoms.
  
  
  RESULTS
  Thirty patients showed initial neurological symptoms (29%). Only two-thirds of them reported chest pain, and most patients without initial neurological symptoms experienced pain (94%). Neurological symptoms were attributable to ischemic stroke (16%), spinal cord ischemia (1%), ischemic neuropathy (11%), and hypoxic encephalopathy (2%). Other frequent symptoms were syncopes (6%) and seizures (3%). In half of the patients, neurological symptoms were transient. Postoperatively, neurological symptoms were found in 48% of all patients encompassing ischemic stroke (14%), spinal cord ischemia (4%), ischemic neuropathy (3%), hypoxic encephalopathy (8%), nerve compression (7%), and postoperative delirium (15%). Overall mortality was 23% and did not significantly differ between patients with and without initial neurological symptoms or complications.
  
  
  CONCLUSIONS
  Aortic dissections might be missed in patients with neurological symptoms but without pain. Neurological findings in elderly hypertensive patients with asymmetrical pulses or cardiac murmur suggest dissection. Especially in patients considered for thrombolytic therapy in acute stroke further diagnostics is essential. Neurological symptoms are not necessarily associated with increased mortality.
authors.affiliation: Department of Neurology, Martin-Luther-University Halle-Wittenberg, Halle/Saale, Germany. Charly.Gaul@gmx.de
authors.forename: Charly
authors.initials: C
authors.lastname: Gaul
authors.forename: Wenke
authors.initials: W
authors.lastname: Dietrich
authors.forename: Ivar
authors.initials: I
authors.lastname: Friedrich
authors.forename: Joachim
authors.initials: J
authors.lastname: Sirch
authors.forename: Frank J
authors.initials: FJ
authors.lastname: Erbguth
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000784:Aortic Dissection / Q000145:classification / Q000150:complications / Q000175:diagnosis* / Q000453:epidemiology; D001014:Aortic Aneurysm / Q000145:classification / Q000150:complications / Q000175:diagnosis* / Q000453:epidemiology; D003943:Diagnostic Techniques, Neurological; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009422:Nervous System Diseases / Q000145:classification / Q000150:complications / Q000175:diagnosis* / Q000453:epidemiology; D012189:Retrospective Studies