[The prognostic value of CA 19-9 in the preoperative work-up of pancreatic cancer patients].
Carbohydrate antigen (CA) 19-9 is produced by adenocarcinomas of the pancreas, stomach, gall bladder, colon, ovary and lung. Serum CA 19-9 is considered the most sensitive marker for pancreatic cancer, being elevated in 75% or more of patients with pancreatic cancer. In all three cases of pancreatic cancer presented, patients died of their disease quite shortly after diagnosis. Preoperative imaging was unsuccessful in exposing the actual advanced state extent of the disease and even during surgery its real extent was underestimated. The only prognostic indicator of the observed rapid disease progression was a very significant elevation of preoperative serum CA 19-9.
Grinbaum
Ronit
R
Department of Surgery, Hadassah-Hebrew University Medical Center (Mount Scopus Campus), Jerusalem, Israel.
Nissan
Aviram
A
Beglaibter
Nahum
N
Cohen
Tzeela
T
Peretz
Tamar
T
Freund
Herbert R
HR
D000328:Adult; D014408:Biomarkers, Tumor / Q000097:blood; D018395:CA-19-9 Antigen / Q000097:blood*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010190:Pancreatic Neoplasms / Q000097:blood* / Q000401:mortality / Q000601:surgery*; D011300:Preoperative Care; D011379:Prognosis; D016019:Survival Analysis
D014408:Biomarkers, Tumor; D018395:CA-19-9 Antigen