title: Human rotavirus G9 and G3 as major cause of diarrhea in hospitalized children, Spain.
abstract: In Spain, diarrhea remains a major cause of illness among infants and young children. To determine the prevalence of rotavirus genotypes and temporal and geographic differences in strain distribution, a structured surveillance study of hospitalized children <5 years of age with diarrhea was initiated in different regions of Spain during 2005. Rotavirus was detected alone in samples from 362 (55.2%) samples and as a coinfection with other viruses in 41 samples (6.3%). Enteropathogenic bacterial agents were detected in 4.9% of samples; astrovirus and norovirus RNA was detected in 3.2% and 12.0% samples, respectively; and adenovirus antigen was detected in 1.8% samples. Including mixed infections, the most predominant G type was G9 (50.6%), followed by G3 (33.0%) and G1 (20.2%). Infection with multiple rotavirus strains was detected in >11.4% of the samples studied during 2005.
authors.affiliation: Instituto de Salud Carlos III, Majadahonda, Madrid, Spain. asanchez@isciii.es
authors.forename: Alicia
authors.initials: A
authors.lastname: Sánchez-Fauquier
authors.forename: Vanessa
authors.initials: V
authors.lastname: Montero
authors.forename: Silvia
authors.initials: S
authors.lastname: Moreno
authors.forename: Monica
authors.initials: M
authors.lastname: Solé
authors.forename: Javier
authors.initials: J
authors.lastname: Colomina
authors.forename: Miren
authors.initials: M
authors.lastname: Iturriza-Gomara
authors.forename: Ana
authors.initials: A
authors.lastname: Revilla
authors.forename: Isabel
authors.initials: I
authors.lastname: Wilhelmi
authors.forename: Jim
authors.initials: J
authors.lastname: Gray
mesh_terms: D001483:Base Sequence; D002675:Child, Preschool; D003967:Diarrhea / Q000453:epidemiology* / Q000821:virology*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D015995:Prevalence; D020133:Reverse Transcriptase Polymerase Chain Reaction / Q000379:methods; D012401:Rotavirus / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*; D012400:Rotavirus Infections / Q000453:epidemiology* / Q000821:virology*; D013030:Spain / Q000453:epidemiology