Clear-cell endocervical adenocarcinoma in a 19-year-old woman.
The incidence of adenocarcinoma of the cervix is increasing within the US, but this diagnostic category is not typically associated with teenaged patients. A report on a case of a 19-year-old woman, with no history of diethylbestrol exposure in uteri, diagnosed with clear-cell endocervical adenocarcinoma is made. Malignant glandular cells were detected on both conventional and Thin Prep gynecologic tests with histologic confirmation. Human papilloma virus (HPV) high-risk type results were negative in this particular case. The patient's unremarkable medical and sexual history prompted us to review the diagnostic criteria and pathogenesis of the disease.
Stewart
Jimmie
J
Cytopathology Section, Department of Pathology and Laboratory Medicine, University of Wisconsin Medical School, 600 Highland Avenue, Madison, WI 53792, USA. jj.stewart@hosp.wisc.edu
Bevans-Wilkins
Kristen
K
Ye
Changhong
C
Kurtycz
Daniel F I
DF
D018262:Adenocarcinoma, Clear Cell / Q000175:diagnosis / Q000209:etiology / Q000473:pathology*; D000328:Adult; D003581:Cytodiagnosis / Q000379:methods; D005260:Female; D006801:Humans; D012307:Risk Factors; D002583:Uterine Cervical Neoplasms / Q000175:diagnosis / Q000209:etiology / Q000473:pathology*; D014626:Vaginal Smears