[Clinical significance of intracellular cytokines in patients with yersiniosis].
OBJECTIVE
To evaluate clinical value of intracellular content of interferon-gamma (If-g), IL-2 and IL-4 in different forms of yersiniosis.


METHODS
The number of If-g, IL-2 and IL-4 producing cells was estimated in 35 patients with generalized (n = 21, group 1) and secondary-focal (n = 14, group 2) forms of yersiniosis.


RESULTS
The control over the number of If-g, IL-2 and IL-4 producing cells in the blood enables valid prognosis of the course and outcome of yersiniosis.


CONCLUSIONS
Pathological processes developing in acute yersiniosis are based on interleukin-dependent immunopathology.
Shepeleva
G K
GK
Shestakova
I V
IV
Popova
O V
OV
Iushchuk
N D
ND
D000328:Adult; D017252:CD3 Complex / Q000032:analysis; D016207:Cytokines / Q000032:analysis; D005260:Female; D006801:Humans; D007371:Interferon-gamma / Q000032:analysis*; D007376:Interleukin-2 / Q000032:analysis*; D015847:Interleukin-4 / Q000032:analysis*; D008297:Male; D011379:Prognosis; D013601:T-Lymphocytes / Q000737:chemistry / Q000276:immunology*; D015009:Yersinia Infections / Q000276:immunology*
D017252:CD3 Complex; D016207:Cytokines; D007376:Interleukin-2; D015847:Interleukin-4; D007371:Interferon-gamma