title: Simple and one-pot protocol for synthesis of indene-spiro-oxindoles involving tandem Prins and Friedel-Crafts reactions.
abstract: [reaction: see text] A simple and one-pot protocol for the synthesis of indene-spiro-oxindole derivatives via TiCl4-mediated reaction between 1,1-diarylethylenes and isatin derivatives involving construction of two carbon-carbon bonds through tandem Prins and intramolecular Friedel-Crafts (PFC) reactions has been described. A plausible mechanism for this transformation is also presented.
authors.affiliation: School of Chemistry, University of Hyderabad, Hyderabad-500 046, India. dbsc@uohyd.ernet.in
authors.forename: Deevi
authors.initials: D
authors.lastname: Basavaiah
authors.forename: Kanumuri Ramesh
authors.initials: KR
authors.lastname: Reddy
mesh_terms: D018360:Crystallography, X-Ray; D005030:Ethylenes / Q000737:chemistry; D006859:Hydrogen / Q000737:chemistry; D007192:Indenes / Q000737:chemistry*; D007211:Indoles / Q000737:chemistry*; D008958:Models, Molecular; D015394:Molecular Structure; D000078183:Oxindoles; D013141:Spiro Compounds / Q000737:chemistry*
chemical_list: D005030:Ethylenes; D007192:Indenes; D007211:Indoles; D000078183:Oxindoles; D013141:Spiro Compounds; C022960:2-oxindole; C093581:indene; D006859:Hydrogen; C036216:ethylene