Multifocal lamellar keratitis following laser in situ keratomileusis.
Over a period of approximately 7 months, multiple subepithelial spots were noted in one or both corneas of some patients examined 2 to 6 months after laser in situ keratomileusis (LASIK). The lesions appeared identical to adenovirus keratitis. The eyes were quiet, had good vision, and no patient had a history of adenoviral keratoconjunctivitis. In all eyes, the lesions resolved spontaneously or with topical steroid eyedrops. All investigations were negative for adenovirus. Corneal laser scanning in vivo confocal microscopy revealed Langerhans cells in the epithelium, which disappeared after the lesions resolved.
Hadden
Osmond Bruce
OB
Eye Institute, Auckland, New Zealand. bruce@hadden.co.nz
Patel
Dipika
D
Gray
Trevor Buchanan
TB
Morris
Antony Trevor
AT
Ring
Charles Peter
CP
D003318:Corneal Opacity / Q000175:diagnosis / Q000209:etiology*; D003319:Corneal Stroma / Q000473:pathology*; D005469:Fluorometholone / Q000627:therapeutic use; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D007634:Keratitis / Q000175:diagnosis / Q000209:etiology*; D020731:Keratomileusis, Laser In Situ / Q000009:adverse effects*; D007801:Langerhans Cells / Q000473:pathology; D018613:Microscopy, Confocal; D009883:Ophthalmic Solutions / Q000627:therapeutic use
D005938:Glucocorticoids; D009883:Ophthalmic Solutions; D005469:Fluorometholone