Six new constituents from the roots of Erythrina variegata.
Three new isoflavonoids, eryvarins M-O (1-3), two new 2-arylbenzofurans, eryvarins P and Q (4 and 5), and a new 3-aryl-2,3-dihydrobenzofuran, eryvarin R (6), together with three known compounds, were isolated from the roots of Erythrina variegata. The structures of these compounds were established by spectroscopic analysis. Eryvarin R (6) is an unusual 3-aryl-2,3-dihydrobenzofuran derivative with a formyl (CHO) group. Eryvarin Q (5) showed potent antibacterial activity against methicillin-resistant Staphylococcus aureus.
Tanaka
Hitoshi
H
Faculty of Pharmacy, Meijo University, Yagoto, Tempaku-ku, Nagoya 468-8503, Japan. hitoshi@ccmfs.meijo-u.ac.jp
Hirata
Miyuki
M
Etoh
Hideo
H
Sako
Magoichi
M
Sato
Masaru
M
Murata
Jin
J
Murata
Hiroko
H
Darnaedi
Dedy
D
Fukai
Toshio
T
D004895:Erythrina; D010936:Plant Extracts / Q000737:chemistry* / Q000302:isolation & purification*; D018517:Plant Roots
D010936:Plant Extracts