title: Treatment of Dientamoeba fragilis infection with paromomycin.
abstract: Treatment with paromomycin (25-35 mg/kg/d for 7 days) was evaluated prospectively in 15 children with Dientamoeba fragilis infection after 1-month follow-up. At the end of the study, parasitologic effectiveness and clinical improvement were observed in 12/15 (80%) and 13/15 (87%) patients, respectively. Paromomycin appears to be an effective drug for treatment of D. fragilis infection in children.
authors.affiliation: Department of Microbiology, Saint-Pierre University Hospital, Brussels, Belgium.
authors.forename: Olivier
authors.initials: O
authors.lastname: Vandenberg
authors.forename: Hichem
authors.initials: H
authors.lastname: Souayah
authors.forename: Françoise
authors.initials: F
authors.lastname: Mouchet
authors.forename: Anne
authors.initials: A
authors.lastname: Dediste
authors.forename: Tom
authors.initials: T
authors.lastname: van Gool
mesh_terms: D000293:Adolescent; D000563:Amebicides / Q000627:therapeutic use*; D000818:Animals; D002648:Child; D002675:Child, Preschool; D004029:Dientamoeba / Q000302:isolation & purification*; D004030:Dientamoebiasis / Q000188:drug therapy*; D005260:Female; D005767:Gastrointestinal Diseases / Q000188:drug therapy* / Q000469:parasitology*; D006801:Humans; D007223:Infant; D008297:Male; D010303:Paromomycin / Q000627:therapeutic use*
chemical_list: D000563:Amebicides; D010303:Paromomycin