[State of the adaptation reactions in the correction process of the negative effect of the stress-factors of chemical nature].
The prolonged influence of lead and fluorine lowers gradually adaptative reserves of organism. Gradual diet supplementation with such bioprotectors as pectin, calcium and triovitum results in renewal of prooxidant-antioxidant balance, that is confirmed by the elevation of antioxidant defence' integral coefficient from 0,09 to 1. The method of estimation of the states of the organism adaptive reactions and the power of action of chemical nature stress-factors in the process of correction of the adaptive violations, using the value of antioxidant defence' integral coefficient is offered. This method is based on correlation of indexes of antioxidant system activity and intensity of lipoperoxidation products.
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D000222:Adaptation, Physiological / Q000187:drug effects*; D000818:Animals; D000975:Antioxidants / Q000008:administration & dosage / Q000378:metabolism / Q000627:therapeutic use*; D002118:Calcium / Q000008:administration & dosage / Q000627:therapeutic use; D007854:Lead / Q000633:toxicity*; D008054:Lipid Peroxides / Q000378:metabolism; D008099:Liver / Q000187:drug effects / Q000201:enzymology / Q000378:metabolism; D008297:Male; D009566:Nitrates / Q000633:toxicity*; D018384:Oxidative Stress / Q000187:drug effects*; D010368:Pectins / Q000008:administration & dosage / Q000627:therapeutic use; D051381:Rats; D017208:Rats, Wistar; D012969:Sodium Fluoride / Q000633:toxicity*; D014815:Vitamins / Q000008:administration & dosage / Q000627:therapeutic use
D000975:Antioxidants; D008054:Lipid Peroxides; D009566:Nitrates; D014815:Vitamins; D007854:Lead; C017461:lead nitrate; D010368:Pectins; D012969:Sodium Fluoride; D002118:Calcium