[Cell therapy in the light of evidence-based medicine].
The results of clinical studies dedicated to treatment with stem cells and other cell technologies were analyzed from the position of evidence-based medicine. Literature data on the safety of cell therapy and the effectiveness of new treatment technologies were summarized according to systems and organs. Cell therapy is becoming more and more applicable to clinical practice in patients with all groups ofpathology. Its safety and effectiveness has been proved in principle, although there are no affirmed algorithms. The authors formulate the main principles of further clinical investigations and substantiate the necessity to conduct research according to blind randomized protocols, which allow meta-analysis.
Bochkov
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D000465:Algorithms; D002318:Cardiovascular Diseases / Q000628:therapy*; D002493:Central Nervous System Diseases / Q000628:therapy*; D019317:Evidence-Based Medicine / Q000379:methods*; D005767:Gastrointestinal Diseases / Q000628:therapy*; D006801:Humans; D009140:Musculoskeletal Diseases / Q000628:therapy*; D033581:Stem Cell Transplantation / Q000009:adverse effects / Q000379:methods*