[Clinical application of medical grade calcium sulfate as a bone graft substitute].
OBJECTIVE
To investigate the clinical effect of medical grade calcium sulfate(Osteoset) as a bone graft substitute.


METHODS
From December 2004 to May 2005, 9 cases of bone defect(limb group) were repaired with Osteoset pellets; bone defect was caused by benign tumor in limbs, including 3 cases of fibroma xanthomas in humerus (1 case) and acetabulum (2 cases), 2 cases of bone cysts in humerus (1) and radius (1), 1 case of nonossifying fibroma, 1 case of ossifying fibroma and 2 cases of osteofibrous dysplasia in femurs. Five cases of lumbar posterolateral fusion (spine group) were treated with Osteoset pellets as autograft volume expander, including 2 cases of lumbar spinal stenosis, 2 cases of lumbar spondylolisthesis and 1 case of lumbar spondylolysis. Radiological method was used to evaluate the repair effect of Osteoset pellets.


RESULTS
The mean follow-up time was 6.2 months (3 to 9 months). Osteoset pellets began to be absorbed after 1 to 3 months of operation, and were totally absorbed and replaced by osseous tissue after 4 to 6 months. No local recurrence was detected in limb group and the function of limbs was normal. At 6 months after operation, all patients in spine group got bony fusion.


CONCLUSIONS
Medical grade calcium sulfate (Osteoset) is an ideal bone graft substitute with excellent bone repair effect.
Liu
Peng
P
Department of Orthopaedics, Daping Hospital and Institute of Field Surgery, Third Military Medical University, Chongqing, 400042, P R China.
Zhao
Jianhua
J
Fan
Weili
W
D000293:Adolescent; D000328:Adult; D000368:Aged; D018786:Bone Substitutes / Q000627:therapeutic use*; D016025:Bone Transplantation / Q000379:methods*; D002133:Calcium Sulfate / Q000627:therapeutic use*; D005121:Extremities / Q000293:injuries; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D013123:Spinal Fusion / Q000379:methods; D013124:Spinal Injuries / Q000601:surgery
D018786:Bone Substitutes; D002133:Calcium Sulfate