title: Combustion synthesis of porous biomaterials.
abstract: This article discusses the unique material manufacturing process of self-propagating high temperature synthesis (SHS) as applied to the making of porous biomaterials. Porous materials have long been considered as the first step toward in-vivo bone tissue engineering and the creation of patient life-time implants. The authors have approached this challenge by utilizing combustion synthesis, to create novel materials such as NiTi + TiC as well as porous forms of materials that are commonly accepted for biomedical applications such as tricalcium phosphate and hydroxyapatite. In the SHS product, physico-chemical properties are controlled by, but not limited to, reactant stoichiometry; green density; particle size of the reactant mix; use or presence of a gasifying agent; heating rate of the reactants and gravity. By balancing these parameters, the energy of the reaction is controlled to create the desired product stoichiometry, porosity, and mechanical properties. SHS provides a means to rapidly manufacture materials, saving time and production costs as well as enabling the synthesis of custom devices through the use of individual molds. Mold materials can range from graphite to paper or paper machete. Combustion synthesis offers a method for the rapid manufacture of affordable, individual biomedical devices that will reduce patient recovery time.
authors.affiliation: Center for Commercial Applications of Combustion in Space, Colorado School of Mines, Golden, Colorado 80401, USA. ruayers@mines.edu
authors.forename: Reed A
authors.initials: RA
authors.lastname: Ayers
authors.forename: Douglas E
authors.initials: DE
authors.lastname: Burkes
authors.forename: Guglielmo
authors.initials: G
authors.lastname: Gottoli
authors.forename: Hu-Chun
authors.initials: HC
authors.lastname: Yi
authors.forename: Fouad
authors.initials: F
authors.lastname: Zhim
authors.forename: L'hocine
authors.initials: L
authors.lastname: Yahia
authors.forename: John J
authors.initials: JJ
authors.lastname: Moore
mesh_terms: D001672:Biocompatible Materials / Q000138:chemical synthesis*; D001696:Biomechanical Phenomena; D002130:Calcium Phosphates; D005740:Gases; D006112:Gravitation; D016062:Porosity; D013696:Temperature; D014025:Titanium
chemical_list: D001672:Biocompatible Materials; D002130:Calcium Phosphates; D005740:Gases; C020243:calcium phosphate; D014025:Titanium