title: The clinical and microbiological correlates of premature rupture of membranes.
abstract: Prematurity is the cause of 85% of neonatal morbidity and mortality. Premature rupture of the membranes (PROM) is associated with 30-40% of preterm deliveries. A case-control study conducted between July 2002 and 2003 examined the correlates and risk factors for PROM in Mysore, India. WBCs in vaginal fluid, leucocytes in urine, UTI and infection with E. coli, S. aureus, C. albicans and BV were significantly associated with PROM. BV, E. coli and WBCs in vaginal fluid were independent risk factors. Screening and treatment of BV and E. coli infection in pregnancy may reduce the risk of PROM.
authors.affiliation: Department of Obstetrics and Gynecology, Holdsworth Memorial Hospital, Mysore--570021, Karnataka, India. hmh@touchtelindia.net
authors.forename: C
authors.initials: C
authors.lastname: Karat
authors.forename: P
authors.initials: P
authors.lastname: Madhivanan
authors.forename: K
authors.initials: K
authors.lastname: Krupp
authors.forename: S
authors.initials: S
authors.lastname: Poornima
authors.forename: N V
authors.initials: NV
authors.lastname: Jayanthi
authors.forename: J S
authors.initials: JS
authors.lastname: Suguna
authors.forename: E
authors.initials: E
authors.lastname: Mathai
mesh_terms: D016022:Case-Control Studies; D005260:Female; D005322:Premature Rupture of Fetal Membranes / Q000209:etiology* / Q000382:microbiology*; D006801:Humans; D007194:India; D007231:Infant, Newborn; D007234:Infant, Premature; D007235:Infant, Premature, Diseases; D007962:Leukocytes / Q000166:cytology; D016015:Logistic Models; D015999:Multivariate Analysis; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000382:microbiology*; D012307:Risk Factors; D014552:Urinary Tract Infections / Q000150:complications* / Q000382:microbiology; D014621:Vagina / Q000166:cytology; D016585:Vaginosis, Bacterial / Q000150:complications* / Q000382:microbiology