Lipid cartography of atherosclerotic plaque by cluster-TOF-SIMS imaging.
Several frozen vessels bearing atherosclerotic lesion were analysed by cluster TOF-SIMS (time-of-flight secondary ion mass spectrometry) to map their lipid (fatty acids, cholesterol, vitamin E, phosphatidic acids, phosphatidylinositols and triglycerides) content at a micrometric resolution.
Mas
Sebastian
S
Fundación Jiménez Díaz, Universidad Autonoma de Madrid, Spain.
Touboul
David
D
Brunelle
Alain
A
Aragoncillo
Paloma
P
Egido
Jesús
J
Laprévote
Olivier
O
Vivanco
Fernando
F
D050197:Atherosclerosis / Q000378:metabolism*; D002339:Carotid Arteries / Q000737:chemistry*; D002784:Cholesterol / Q000032:analysis; D005227:Fatty Acids / Q000032:analysis; D006801:Humans; D008055:Lipids / Q000032:analysis*; D008297:Male; D010712:Phosphatidic Acids / Q000032:analysis; D010716:Phosphatidylinositols / Q000032:analysis; D018629:Spectrometry, Mass, Secondary Ion; D014280:Triglycerides / Q000032:analysis; D014810:Vitamin E / Q000032:analysis
D005227:Fatty Acids; D008055:Lipids; D010712:Phosphatidic Acids; D010716:Phosphatidylinositols; D014280:Triglycerides; D014810:Vitamin E; D002784:Cholesterol