The dispersed neuroendocrine system, its bronchopulmonary elements, and neuroendocrine tumors presumed to be derived from them: myths, mistaken notions, and misunderstandings.
The increasing recognition of the dispersed neuroendocrine system and its importance in human physiology has impacted our understanding of physiology, pathophysiology, and histopathology. It has been the subject of a great deal of controversy and debate, giving rise to certain misunderstandings. This article attempts to put some of these issues in perspective, especially as they relate to the bronchopulmonary tree.
Warren
William H
WH
Department of Cardiovascular-Thoracic Surgery, Rush University Medical Center, Chicago, IL 60612, USA. wwarren@rush.edu
Hammar
Samuel P
SP
D001980:Bronchi / Q000473:pathology*; D001984:Bronchial Neoplasms / Q000473:pathology*; D001999:Bronchoscopy; D006801:Humans; D008168:Lung / Q000473:pathology; D008175:Lung Neoplasms / Q000473:pathology*; D018358:Neuroendocrine Tumors / Q000473:pathology*; D009490:Neurosecretory Systems / Q000502:physiology / Q000503:physiopathology*; D018570:Risk Assessment