Air-induced anti-Markovnikov addition of secondary phosphine oxides and H-phosphinates to alkenes.
[reaction: see text] Air (oxygen) induces the addition of secondary phosphine oxides and H-phosphinates to alkenes to selectively produce the corresponding anti-Markovnikov adducts in good to high yields. Mechanistic studies show that the addition probably proceeds via a radical chain mechanism.
Hirai
Takayoshi
T
National Institute of Advanced Industrial Science and Technology, Tsukuba, Ibaraki 305-8565, Japan.
Han
Li-Biao
LB