title: Isomeric eremophilane lactones from Senecio tsoongianus.
abstract: From the whole plant of Senecio tsoongianus, two pairs of epimers, tsoongianolides A (1) and B (2), and tsoongianolides C (3) and D (4), and two new sesquiterpene lactones, tsoongianolides E (5) and F (6), all of which possess the eremophilane skeleton, were isolated. Two known eremophilane dimers (7) and (8) were also obtained from this species. Their absolute structures were elucidated by 1D- and 2D-NMR techniques and by X-ray diffraction studies, along with chemical evidence.
authors.affiliation: Department of Traditional Chinese Medicine and Natural Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310031, PR China. dryuzhao@zju.edu.cn
authors.forename: Yu
authors.initials: Y
authors.lastname: Zhao
authors.forename: Hao
authors.initials: H
authors.lastname: Jiang
authors.forename: Murray
authors.initials: M
authors.lastname: MacLeod
authors.forename: Simon
authors.initials: S
authors.lastname: Parsons
authors.forename: David W H
authors.initials: DW
authors.lastname: Rankin
authors.forename: Peng
authors.initials: P
authors.lastname: Wang
authors.forename: Christopher H K
authors.initials: CH
authors.lastname: Cheng
authors.forename: Hao
authors.initials: H
authors.lastname: Shi
authors.forename: Xiaojiang
authors.initials: X
authors.lastname: Hao
authors.forename: Françoise
authors.initials: F
authors.lastname: Guéritte
mesh_terms: D007536:Isomerism; D007783:Lactones / Q000737:chemistry* / Q000302:isolation & purification; D009281:Naphthalenes / Q000737:chemistry* / Q000302:isolation & purification; D010936:Plant Extracts / Q000737:chemistry / Q000302:isolation & purification; D018514:Plant Structures; D000081223:Polycyclic Sesquiterpenes; D012674:Senecio; D012717:Sesquiterpenes
chemical_list: D007783:Lactones; D009281:Naphthalenes; D010936:Plant Extracts; D000081223:Polycyclic Sesquiterpenes; D012717:Sesquiterpenes; C018286:eremophilane compounds