title: Hereditary benign intraepithelial dyskeratosis: a new case?
abstract: Hereditary benign intraepithelial dyskeratosis (HBID) is a rare disorder first described in 1960. To date, all but one published case trace their ancestry back to an Indian tribe in North Carolina. Affected patients usually develop asymptomatic ocular and oral lesions. The latter may resemble other dermatologic conditions that affect the oral mucosa, such as white sponge nevus. This report describes a case of a Brazilian patient who showed clinical and histological features of HBID, which appears to be the first reported case in South America. Although genetic analysis could not be carried out, the family history suggests a genetic etiology.
authors.affiliation: Department of Oral Surgery and Pathology, School of Dentistry, Federal University of Minas Gerais, Minas Gerais, Brazil.
authors.forename: Bruno Correia
authors.initials: BC
authors.lastname: Jham
authors.forename: Ricardo Alves
authors.initials: RA
authors.lastname: Mesquita
authors.forename: Maria Cássia Ferreira
authors.initials: MC
authors.lastname: Aguiar
authors.forename: Maria Auxiliadora Vieira
authors.initials: MA
authors.lastname: Carmo
mesh_terms: D000328:Adult; D003229:Conjunctival Diseases / Q000235:genetics / Q000473:pathology; D003937:Diagnosis, Differential; D019871:Dyskeratosis Congenita / Q000235:genetics* / Q000473:pathology; D006222:Hamartoma / Q000235:genetics / Q000473:pathology; D006801:Humans; D006965:Hyperplasia; D007972:Leukoplakia, Oral / Q000235:genetics / Q000473:pathology; D008297:Male; D009061:Mouth Mucosa / Q000473:pathology