title: Impulsiveness in obsessive-compulsive disorder: results from a family study.
abstract: OBJECTIVE
  Although obsessive-compulsive disorder (OCD) is usually conceptualized as an anxiety disorder some studies suggested it to be a deficit of impulse control. The purpose of this study was to assess impulsiveness in OCD families and compare it to control families.
  
  
  METHODS
  Seventy cases and their 139 relatives were compared with 70 controls and their 134 relatives from a German family study on OCD (German Epidemiologic Network for OCD Studies). All subjects were interviewed and diagnosed according DSM-IV criteria and were administered the Barratt Impulsiveness Scale (BIS) and PADUA-Inventory to assess obsessive-compulsive symptoms.
  
  
  RESULTS
  OCD subjects had significantly higher scores of cognitive impulsiveness. However, first-degree relatives of OCD cases and of controls had comparable BIS-11 scores. Significant associations of aggressive obsessions and checking with cognitive impulsiveness were found.
  
  
  CONCLUSIONS
  OCD is a severe mental disorder that is characterized by a lack of cognitive inhibition. However, impulsiveness does not represent a familial trait in families of OCD subjects.
authors.affiliation: Department of Psychiatry and Psychotherapy, University of Greifswald, Stralsund, Germany. ettelt@uni-greifswald.de
authors.forename: S
authors.initials: S
authors.lastname: Ettelt
authors.forename: S
authors.initials: S
authors.lastname: Ruhrmann
authors.forename: S
authors.initials: S
authors.lastname: Barnow
authors.forename: F
authors.initials: F
authors.lastname: Buthz
authors.forename: A
authors.initials: A
authors.lastname: Hochrein
authors.forename: K
authors.initials: K
authors.lastname: Meyer
authors.forename: S
authors.initials: S
authors.lastname: Kraft
authors.forename: C
authors.initials: C
authors.lastname: Reck
authors.forename: R
authors.initials: R
authors.lastname: Pukrop
authors.forename: J
authors.initials: J
authors.lastname: Klosterkötter
authors.forename: P
authors.initials: P
authors.lastname: Falkai
authors.forename: W
authors.initials: W
authors.lastname: Maier
authors.forename: M
authors.initials: M
authors.lastname: Wagner
authors.forename: H J
authors.initials: HJ
authors.lastname: Freyberger
authors.forename: H J
authors.initials: HJ
authors.lastname: Grabe
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D015897:Comorbidity; D003430:Cross-Sectional Studies; D039721:Diagnostic and Statistical Manual of Mental Disorders; D007174:Disruptive, Impulse Control, and Conduct Disorders / Q000175:diagnosis / Q000453:epidemiology / Q000235:genetics*; D005260:Female; D005858:Germany; D006801:Humans; D007266:Inhibition, Psychological; D008297:Male; D008875:Middle Aged; D009771:Obsessive-Compulsive Disorder / Q000175:diagnosis / Q000453:epidemiology / Q000235:genetics*; D010555:Personality Inventory; D010641:Phenotype; D012737:Sex Factors; D013223:Statistics as Topic