title: In vitro activities of tigecycline and eight other antimicrobials against different Nocardia species identified by molecular methods.
abstract: The in vitro activities of tigecycline and other antimicrobials against 51 isolates of Nocardia spp. were evaluated. MIC(90)s and MIC ranges were as follows: tigecycline, 4 and < or =0.06 to 8 mg/liter, respectively; minocycline, 2 and < or =0.06 to 2 mg/liter, respectively; linezolid, 1 and < or =0.06 to 2 mg/liter, respectively; moxifloxacin, 2 and < or =0.06 to >64 mg/liter, respectively; ertapenem, 32 and < or =0.06->64 mg/liter, respectively; imipenem, 2 and < or =0.06 to >64 mg/liter, respectively; meropenem, 8 and < or =0.06 to >64 mg/liter, respectively; amikacin, 1 and < or =0.06 to 32 mg/liter, respectively; and trimethoprim-sulfamethoxazole, 1/19 and < or =0.5/9.5 to >2/38 mg/liter, respectively.
authors.affiliation: Servicio de Microbiología Clínica y Enfermedades Infecciosas, Hospital General Universitario Gregorio Marañón, Dr. Esquerdo 46, 28007 Madrid, Spain. ecercenado@terra.es
authors.forename: Emilia
authors.initials: E
authors.lastname: Cercenado
authors.forename: Mercedes
authors.initials: M
authors.lastname: Marín
authors.forename: Mónica
authors.initials: M
authors.lastname: Sánchez-Martínez
authors.forename: Oscar
authors.initials: O
authors.lastname: Cuevas
authors.forename: José
authors.initials: J
authors.lastname: Martínez-Alarcón
authors.forename: Emilio
authors.initials: E
authors.lastname: Bouza
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D006801:Humans; D008826:Microbial Sensitivity Tests; D008911:Minocycline / Q000031:analogs & derivatives* / Q000494:pharmacology; D009615:Nocardia / Q000187:drug effects* / Q000235:genetics; D009617:Nocardia Infections / Q000382:microbiology; D012150:Polymorphism, Restriction Fragment Length; D020133:Reverse Transcriptase Polymerase Chain Reaction; D000078304:Tigecycline
chemical_list: D000900:Anti-Bacterial Agents; D000078304:Tigecycline; D008911:Minocycline