Ultraviolet recall reaction after total body irradiation, etoposide, and methotrexate therapy.
Ultraviolet (UV) reactivation reactions are rare and can occur in areas of prior sunburn or UV light therapy after the administration of chemotherapy, antibiotics, and other medications. Reactions may occur within days, as described after methotrexate therapy, or may appear months later, as described with ampicillin. Such reactions have been variably termed "UV recall," "sunburn recall," "photo recall," and "photodermatitis reactivation," making classification difficult. We report a UV reactivation reaction in a patient with acute lymphocytic leukemia treated with total body irradiation, etoposide, and methotrexate. We propose the terms "UV recall" and "UV enhancement" be used in future reports to classify UV reactivation reactions in a scheme analogous to the terminology for cutaneous reactions after radiotherapy.
Goldfeder
Katherine L
KL
University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA.
Levin
Joshua M
JM
Katz
Kenneth A
KA
Clarke
Loren E
LE
Loren
Alison W
AW
James
William D
WD
D000964:Antimetabolites, Antineoplastic / Q000009:adverse effects* / Q000627:therapeutic use; D000972:Antineoplastic Agents, Phytogenic / Q000009:adverse effects* / Q000627:therapeutic use; D005047:Etoposide / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008727:Methotrexate / Q000009:adverse effects* / Q000627:therapeutic use; D008875:Middle Aged; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000628:therapy*; D012008:Recurrence; D012867:Skin / Q000473:pathology; D013471:Sunburn / Q000209:etiology; D014466:Ultraviolet Rays / Q000009:adverse effects*; D014916:Whole-Body Irradiation / Q000009:adverse effects*
D000964:Antimetabolites, Antineoplastic; D000972:Antineoplastic Agents, Phytogenic; D005047:Etoposide; D008727:Methotrexate