title: Prolonged decrease in stress reactivity caused by dehydroepiandrosterone sulfate.
abstract: In male rats exposed to repeated stress, the decrease in stress reactivity produced by subcutaneous injection of dehydroepiandrosterone sulfate (recorded by the decrease in stress-induced concentrations of corticosterone and adrenocorticotropic hormone in blood plasma) was observed 1-6 days postinjection and involved central regulatory mechanisms.
authors.affiliation: Institute of Physiology, Siberian Division, Russian Academy of Medical Sciences, Novosibirsk. t.a.obut@iph.ma.nsc.ru
authors.forename: T A
authors.initials: TA
authors.lastname: Obut
authors.forename: M V
authors.initials: MV
authors.lastname: Ovsyukova
authors.forename: O P
authors.initials: OP
authors.lastname: Cherkasova
mesh_terms: D000324:Adrenocorticotropic Hormone / Q000097:blood; D000818:Animals; D002851:Chromatography, High Pressure Liquid; D003345:Corticosterone / Q000097:blood; D019314:Dehydroepiandrosterone Sulfate / Q000008:administration & dosage / Q000627:therapeutic use*; D008297:Male; D051381:Rats; D013312:Stress, Physiological / Q000188:drug therapy* / Q000503:physiopathology*; D013997:Time Factors
chemical_list: D019314:Dehydroepiandrosterone Sulfate; D000324:Adrenocorticotropic Hormone; D003345:Corticosterone