[Validity of Framingham criteria as a clinical test for systolic heart failure].
BACKGROUND
To assess validity and clinical usefulness of the Framingham clinical criteria for the diagnosis of systolic heart failure.


METHODS
A descriptive cross-sectional trial. The study population was made up of the patients who went to the emergency Department at the Hospital de Elche, Elche, Spain, with cardiac dyspnoea. The method applied was a validation study in which a value of 0.45 of the left ventricular ejection fraction was taken as a sign of certitude and compared to the presence/absence of the Framingham clinical criteria. The study indicators were: sensitivity, specificity, positive predictive value, negative predictive value, positive probability quotient and negative probability quotient.


RESULTS
The trial included 224 patients. The most frequent major criteria were: lung rales (93%), megalocardia (85.9%) and paroxysmal nocturnal dyspnoea or orthopnea (75.8%). The most important minor criteria were: exertional dyspnoea (89.2%), pleural effusion (82.8%) and lower limb oedemas (70.1%). The values that were considered as a sign of left ventricular systolic failure (0.45) proved to have good sensitivity and positive predictive value (96.4% and 97%, respectively). Clinical usefulness indicators obtained a positive probability quotient of 1.52 and a negative predictive value of 0.09.


CONCLUSIONS
The Framingham clinical criteria have excellent sensitivity but poor specificity. The absence of these criteria totally excludes the diagnosis if the value of the left ventricular ejection fraction is 0.45 (A category) but their presence does not confirm the diagnosis because of the high amount of false-positive findings (D category).
Jimeno Sainz
A
A
Servicio de Medicina Interna, Hospital Ernest Lluch, Calatayud, Zaragoza. ajimenosa@hotmail.com
Gil
V
V
Merino
J
J
García
M
M
Jordán
A
A
Guerrero
L
L
D000368:Aged; D003935:Diagnostic Techniques, Cardiovascular; D005260:Female; D006333:Heart Failure / Q000175:diagnosis*; D006801:Humans; D008297:Male; D008875:Middle Aged