Antioxidant quinonemethide triterpenes from Salacia campestris.
A new quinonemethide triterpene named as salacin, has been isolated from the root bark of Salacia campestris in addition to the known pristimerin, maytenin, 20alpha-hydroxymaytenin, and netzahualcoyene. Salacin was identified on the basis of NMR-spectral and mass spectrometric analysis. The free-radical scavenging activities of the quinonemethide triterpenes salacin (1), pristimerin (2), maytenin (3), 20alpha-hydroxymaytenin (4), and netzahualcoyene (5) towards DPPH have been evaluated and showed absorbance variation (deltaA) of 19, 20, 39, 28, 55, and 10%, respectively, having rutin (74% at 50 microM) and BHT (7% at 50 microM) as standard compounds.
Carvalho
Paulo R F
PR
Instituto de Química, Universidade Estadual Paulista, CP 355, CEP14801-900, Araraquara, SP, Brazil.
Silva
Dulce H S
DH
Bolzani
Vanderlan S
VS
Furlan
Maysa
M
D000975:Antioxidants / Q000302:isolation & purification / Q000494:pharmacology*; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D015394:Molecular Structure; D049918:Salacia / Q000737:chemistry*; D013055:Spectrophotometry, Infrared; D014315:Triterpenes / Q000302:isolation & purification / Q000494:pharmacology*
D000975:Antioxidants; D014315:Triterpenes