title: [About correlation of dysfunction of the thyroid gland with fibrocystic diseases in women].
abstract: The reference data contain a lot of information on the interrelation between destroying of a thyroid gland and fibrocystic diseases. However contradictions in these data proves that this issue is not solved completely. The aim of the given study was the investigation of interrelations between frequency of occurrence of pathology of a functional condition of the thyroid gland and the frequency of occurrence of fibrocystic diseases. 90 women aged 23-50 were investigated. Concentration of thyroxin (FT4), thyrotrophic hormone (TSH), titers of antibodies to thyreoperoxidase, microsomal fraction of thyreocytes and thyreoglobulin were measured by ELISA. Palpation and ultrasonic investigations of thyroid and mammary glands were used, morphology of central formations of mammary glands according to indications was also carried out. A special questionnaire was completed for each patient. Our investigations showed that along with the declining of function of thyroid gland and the increased level of TSH in the blood, the risk of development of fibrocystic diseases is increased twice.
authors.forename: K G
authors.initials: KG
authors.lastname: Mardaleishvili
authors.forename: G G
authors.initials: GG
authors.lastname: Nemsadze
authors.forename: D S
authors.initials: DS
authors.lastname: Metreveli
authors.forename: T L
authors.initials: TL
authors.lastname: Roinishvili
mesh_terms: D000328:Adult; D015415:Biomarkers / Q000097:blood; D018450:Disease Progression; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D005348:Fibrocystic Breast Disease / Q000453:epidemiology / Q000209:etiology* / Q000473:pathology; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D008875:Middle Aged; D012307:Risk Factors; D012720:Severity of Illness Index; D013959:Thyroid Diseases / Q000097:blood / Q000150:complications* / Q000175:diagnosis; D013972:Thyrotropin / Q000097:blood*; D013974:Thyroxine / Q000097:blood*
chemical_list: D015415:Biomarkers; D013972:Thyrotropin; D013974:Thyroxine