title: Synthesis of nanostructured bio-related materials by hybridization of synthetic polymers with polysaccharides or saccharide residues.
abstract: In the first part of this review, we describe the synthesis of nanostructured hybrid materials composed of polysaccharides and synthetic polymers. Amylose-synthetic polymer inclusion complexes were synthesized by amylose-forming polymerization using phosphorylase enzyme in the presence of synthetic polymers such as polyethers and polyesters. Alginate-polymethacrylate hybrid materials were prepared by free-radical polymerization of cationic methacrylate in the presence of sodium alginate. These methods allow the simultaneous control of the nanostructure with polymerization, giving well-defined hybrid materials. In the second part of this review, we describe the synthesis of novel glycopolymers with rigid structures. Polyaniline-based glycopolymers were synthesized by means of oxidative polymerization of N-glycosylaniline. Polysiloxane-based glycopolymers were prepared by means of introduction of sugar-lactone to the rodlike polysiloxane. These glycopolymers had regular higher-ordered structures due to their rigid polymer backbones, resulting in control of the three-dimensional array of sugar-residues.
authors.affiliation: Department of Nano-structured and Advanced Materials, Graduate School of Science and Engineering, Kagoshima University, Korimoto, Kagoshima 890-0065, Japan.
authors.forename: Yoshiro
authors.initials: Y
authors.lastname: Kaneko
authors.forename: Jun-Ichi
authors.initials: J
authors.lastname: Kadokawa
mesh_terms: D002236:Carbohydrate Conformation; D002240:Carbohydrate Sequence; D008969:Molecular Sequence Data; D049329:Nanostructures; D036103:Nanotechnology / Q000379:methods*; D011108:Polymers / Q000138:chemical synthesis*; D011134:Polysaccharides / Q000138:chemical synthesis*; D013816:Thermodynamics
chemical_list: D011108:Polymers; D011134:Polysaccharides