[Expression of c-myc protein on rats' brains after brain concussion].
OBJECTIVE
To study the changes of expression of c-myc protein on rats' brains after brain concussion.


METHODS
sixty rats were randomly divided into brain concussion groups and control group. The expression of c-myc protein was microscopically observed by immunohistochemical method.


RESULTS
No expression of c-myc protein in control group were observed. However, positive expression of c-myc protein in some neurons was seen at 20 min after brain concussion, and reach to the peak at 8h after brain concussion and then decreased gradually.


CONCLUSIONS
These findings suggest that the detection of c-myc protein could be an index of diagnosis of brain concussion.
Fang
Wei-Hua
WH
Department of forensic medicine, Wannan medical college, Wuhu 241001, China. weihua_3110@yahoo.com.cn
Wang
Dong-Liang
DL
Wang
Feng
F
D000818:Animals; D001921:Brain / Q000378:metabolism* / Q000473:pathology; D001924:Brain Concussion / Q000378:metabolism* / Q000473:pathology; D001933:Brain Stem / Q000378:metabolism / Q000473:pathology; D002540:Cerebral Cortex / Q000378:metabolism / Q000473:pathology; D004195:Disease Models, Animal; D005260:Female; D007150:Immunohistochemistry; D008297:Male; D009474:Neurons / Q000378:metabolism / Q000473:pathology; D016271:Proto-Oncogene Proteins c-myc / Q000378:metabolism*; D011897:Random Allocation; D051381:Rats; D017207:Rats, Sprague-Dawley; D013997:Time Factors
D016271:Proto-Oncogene Proteins c-myc