[A case of progressive gastric carcinoma accompanied by disseminated carcinomatosis of bone marrow due to bone metastasis with DIC recovery by joint administration of 5-FU and paclitaxel].
A 54-year-old male visited our hospital with the chief complaint of anorexia. Based on various tests, a diagnosis of scirrhous gastric carcinoma accompanied by bone metastasis and liver metastasis was made. As DIC developed following hospital admission, 5-FU and PTX therapy (5-FU at 600 mg/m(2), 24-hour continuous infusion, day 1-5 and PTX at 80 mg/m(2), iv, day 8, 15, 22) were administered. Although primary foci, bone metastasis, and liver metastasis were observed by image diagnostic procedures, recovery from DIC was achieved. 5-FU+PTX therapy is considered to be effective for DIC due to bone metastasis of gastric carcinoma.
Satoh
Daisuke
D
Dept. of Surgery, Hiroshima City Hospital.
Ninomiya
Motoki
M
Umeoka
Tatsuya
T
Harano
Masao
M
Sasaki
Hiroshi
H
Aoki
Hideki
H
Onoda
Tadashi
T
Shiozaki
Yoshihiro
Y
Ohno
Satoru
S
Higaki
Kenji
K
Takakura
Naohisa
N
D002293:Adenocarcinoma, Scirrhous / Q000188:drug therapy* / Q000556:secondary; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D019046:Bone Marrow Neoplasms / Q000188:drug therapy* / Q000556:secondary; D001859:Bone Neoplasms / Q000188:drug therapy* / Q000556:secondary; D004211:Disseminated Intravascular Coagulation / Q000209:etiology*; D004334:Drug Administration Schedule; D005472:Fluorouracil / Q000008:administration & dosage; D006801:Humans; D008113:Liver Neoplasms / Q000188:drug therapy* / Q000556:secondary; D008297:Male; D008875:Middle Aged; D017239:Paclitaxel / Q000008:administration & dosage; D013274:Stomach Neoplasms / Q000188:drug therapy* / Q000473:pathology*
D017239:Paclitaxel; D005472:Fluorouracil