title: Inhibition of lesion-induced neurogenesis impaired behavioral recovery in adult ring doves.
abstract: We have previously shown that electrolytic lesion-induced neurogenesis in the ventromedial nucleus of the hypothalamus (VMN) is significantly correlated with the recovery of courtship behavior in adult male ring doves. Here we revealed that reduction of lesion-induced neurogenesis in VMN impaired the behavioral recovery suggesting therefore a causal link between neurogenesis and behavioral recovery. Our results lend support that adult neurogenesis is latent in repair of injured brain.
authors.affiliation: Department of Psychology, Rutgers University, Newark, NJ 07102, United States. chenga@ohsu.edu
authors.forename: Gang
authors.initials: G
authors.lastname: Chen
authors.forename: Mei-Fang
authors.initials: MF
authors.lastname: Cheng
mesh_terms: D000596:Amino Acids; D000818:Animals; D002452:Cell Count / Q000379:methods; D010856:Columbidae; D005904:Glial Fibrillary Acidic Protein / Q000378:metabolism; D007150:Immunohistochemistry; D007266:Inhibition, Psychological; D008297:Male; D009474:Neurons / Q000502:physiology*; D010751:Phosphopyruvate Hydratase / Q000378:metabolism; D020127:Recovery of Function / Q000502:physiology*; D012726:Sexual Behavior, Animal; D014697:Ventromedial Hypothalamic Nucleus / Q000293:injuries / Q000473:pathology*
chemical_list: D000596:Amino Acids; D005904:Glial Fibrillary Acidic Protein; C098463:dolaisoleucine; D010751:Phosphopyruvate Hydratase