Iridium-catalyzed conversion of alcohols into amides via oximes.
[reaction: see text] The iridium catalyst [Ir(Cp*)Cl2]2 is effective for the rearrangement of oximes to furnish amides. The reaction has been combined with catalytic transfer hydrogenation between an alcohol and alkene to allow the conversion of alcohols into amides in a one-pot process.
Owston
Nathan A
NA
Department of Chemistry, University of Bath, Claverton Down, Bath BA2 7AY, UK.
Parker
Alexandra J
AJ
Williams
Jonathan M J
JM
D000438:Alcohols / Q000737:chemistry*; D000577:Amides / Q000737:chemistry*; D002384:Catalysis; D007495:Iridium / Q000737:chemistry*; D015394:Molecular Structure; D010084:Oxidation-Reduction; D010091:Oximes / Q000737:chemistry*
D000438:Alcohols; D000577:Amides; D010091:Oximes; D007495:Iridium