Investigation of KIR gene frequencies in type 1 diabetes mellitus.
The frequency of killer immunoglobulinlike receptors (KIR) genes was examined in type 1 diabetes mellitus patients and controls from Finland. The KIR gene 2DS5 was significantly decreased in patients versus controls, but this was no longer significant after correction for the number of comparisons made.
Middleton
Derek
D
Northern Ireland Histocompatibility and Immunogenetics Laboratory, City Hospital, Belfast, and University of Ulster, Coleraine, Northern Ireland. derek.middleton@bll.n-i.nhs.uk
Halfpenny
Iris
I
Meenagh
Ashley
A
Williams
Fionnula
F
Sivula
Jyrki
J
Tuomilehto-Wolf
Eva
E
D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D003922:Diabetes Mellitus, Type 1 / Q000235:genetics* / Q000276:immunology; D005260:Female; D005387:Finland; D005787:Gene Frequency / Q000276:immunology; D006801:Humans; D008297:Male; D008875:Middle Aged; D020559:Monomeric GTP-Binding Proteins / Q000235:genetics* / Q000276:immunology; D020125:Mutation, Missense / Q000276:immunology
C490245:GEM protein, human; D020559:Monomeric GTP-Binding Proteins