Five new iridoids from Patrinia rupestris.
Five new iridoids, namely rupesin A-E (1-5, resp.), together with six known iridoids, 6-11, were isolated from the roots of Patrinia rupestris. Their structures were elucidated by spectroscopic methods including IR, UV, MS, and 1D- and 2D-NMR experiments, and comparison with data of known analogues. Compounds 4 and 11, compounds 1, 2, 5, 6, 8, 9, and 10, and compounds 3, 4, and 8 showed significant antibacterial activities against Bacillus subtilis, Escherichia coli, and Staphylococcus aureus, respectively.
Yang
Xiu-Ping
XP
State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou, Gansu, 730000, PR China.
Li
Er-Wei
EW
Zhang
Qi
Q
Yuan
Cheng-Shan
CS
Jia
Zhong-Jian
ZJ
D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000494:pharmacology; D001412:Bacillus subtilis / Q000187:drug effects; D004926:Escherichia coli / Q000187:drug effects; D039823:Iridoids / Q000737:chemistry* / Q000302:isolation & purification* / Q000494:pharmacology; D015394:Molecular Structure; D032405:Patrinia / Q000737:chemistry*; D018517:Plant Roots / Q000737:chemistry; D013057:Spectrum Analysis; D013211:Staphylococcus aureus / Q000187:drug effects
D000900:Anti-Bacterial Agents; D039823:Iridoids