title: TOR regulation: sorting out the answers.
abstract: Components involved in vesicle trafficking processes such as secretion, endocytosis, and autophagy are gaining recognition as important regulators and effectors of target of rapamycin (TOR) signaling. A recent report by now implicates Pmr1, a secretory pathway Ca(2+)/Mn(2+) ATPase located in the Golgi apparatus, as a novel regulator of TOR and its downstream targets in yeast.
authors.affiliation: Department of Genetics, Cell Biology & Development, University of Minnesota, 6-160 Jackson Hall, 321 Church Street SE, Minneapolis, MN 55455, USA. neufeld@ahc.umn.edu
authors.forename: Thomas P
authors.initials: TP
authors.lastname: Neufeld
mesh_terms: D000818:Animals; D000252:Calcium-Transporting ATPases / Q000235:genetics / Q000378:metabolism*; D006056:Golgi Apparatus / Q000378:metabolism; D006801:Humans; D008954:Models, Biological; D018832:Molecular Chaperones / Q000378:metabolism*; D016506:Pemphigus, Benign Familial / Q000378:metabolism; D019869:Phosphatidylinositol 3-Kinases / Q000378:metabolism; D017346:Protein Serine-Threonine Kinases; D012441:Saccharomyces cerevisiae / Q000378:metabolism*; D029701:Saccharomyces cerevisiae Proteins / Q000378:metabolism*; D015398:Signal Transduction; D022161:Transport Vesicles / Q000378:metabolism
chemical_list: D000252:Calcium-Transporting ATPases; D018832:Molecular Chaperones; D019869:Phosphatidylinositol 3-Kinases; D017346:Protein Serine-Threonine Kinases; D029701:Saccharomyces cerevisiae Proteins; C101767:SSC1 protein, S cerevisiae; C500749:target of rapamycin protein, S cerevisiae; C403624:ATP2C1 protein, human