title: Beneficial effect of long-acting injectable risperidone on the neurocognitive deficit of a schizophrenic patient: A case report.
abstract: We report the case of a 37-year-old female patient suffering from schizophrenia, disorganized type. Adherence to treatment was always a major problem. During the last 2 years the patient was disorganized and was refusing treatment. Since the patient was already receiving a very high (double) dose per os, it was decided to administer two 50 ml ampoules of long-acting, injectable risperidone plus 5 mg of haloperidol per os daily. After 80 days of treatment, all positive, negative and even neurocognitive symptoms improved markedly. Extrapyramidal side effects did not appear at any stage of treatment. The most impressive neurocognitive improvement concerned the clock drawing test, which was in parallel with her improvement in both the positive and negative symptoms of the PANSS.
authors.affiliation: 3rd Department of Psychiatry, Aristotle University of Thessaloniki, Greece. kfount@panafonet.gr
authors.forename: K N
authors.initials: KN
authors.lastname: Fountoulakis
authors.forename: S
authors.initials: S
authors.lastname: Kantartzis
authors.forename: M
authors.initials: M
authors.lastname: Siamouli
authors.forename: P
authors.initials: P
authors.lastname: Panagiotidis
authors.forename: S G
authors.initials: SG
authors.lastname: Kaprinis
authors.forename: E
authors.initials: E
authors.lastname: Kourila
authors.forename: A
authors.initials: A
authors.lastname: Lacovides
authors.forename: G S
authors.initials: GS
authors.lastname: Kaprinis
mesh_terms: D000328:Adult; D014150:Antipsychotic Agents / Q000008:administration & dosage* / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007273:Injections, Intramuscular; D010349:Patient Compliance; D011569:Psychiatric Status Rating Scales; D018967:Risperidone / Q000008:administration & dosage* / Q000627:therapeutic use; D012559:Schizophrenia / Q000188:drug therapy*
chemical_list: D014150:Antipsychotic Agents; D018967:Risperidone