Evaluation of the SAS Legionella Test, a new immunochromatographic assay for the detection of Legionella pneumophila serogroup 1 antigen in urine.
This study evaluated a new immunochromatographic assay (SAS Legionella Test) for its ability to detect Legionella pneumophila serogroup 1 antigen in urine. Results were compared with those obtained using the Binax Now urinary antigen test. Sensitivity and specificity were estimated as 82.9% and 99.0%, respectively, for the SAS Legionella Test, and 91.4% and 100%, respectively, for the Binax Now urinary antigen test. The sensitivity of both tests increased to 97.1% (p 0.009) and 94.2% (p 0.7), respectively, if the tests were examined after 1 h.
Diederen
B M W
BM
Laboratory for Medical Microbiology and Immunology, St Elisabeth Hospital, Tilburg, The Netherlands. bramdiederen@gmail.com
Peeters
M F
MF
D000942:Antigens, Bacterial / Q000652:urine*; D015415:Biomarkers / Q000652:urine; D002845:Chromatography; D006801:Humans; D007159:Immunologic Tests / Q000379:methods; D016952:Legionella pneumophila / Q000276:immunology* / Q000302:isolation & purification; D007877:Legionnaires' Disease / Q000175:diagnosis* / Q000652:urine; D012680:Sensitivity and Specificity
D000942:Antigens, Bacterial; D015415:Biomarkers