[Research and prospect on reducing the toxicity and enhancing the efficacy of Tipterygium wilfordii by combined use of Chinese medicine].
Researches in recent close to dozen years concerning Tripterygium wilfordii (TW) toxicity-reducing and efficacy-enhancing by combined use of Chinese medicine in treating intractable diseases such as rheumatoid arthritis, nephropathy, psoriasis etc. were summarized in this paper. Furthermore, the therapeutic mechanisms and adverse reaction of TW were elaborated and how to arrange properly the TCM hebal drugs used in combination was analyzed.
Li
Bo
B
Postgraduate Division, Liaoning University of Traditional Chinese Medicine, Shenyang. 1shengyanglibo@sina.com
Zhou
Xin-xin
XX
Liang
Mao-xin
MX
D000818:Animals; D001172:Arthritis, Rheumatoid / Q000188:drug therapy; D004338:Drug Combinations; D064420:Drug-Related Side Effects and Adverse Reactions / Q000139:chemically induced / Q000517:prevention & control; D004365:Drugs, Chinese Herbal / Q000009:adverse effects* / Q000627:therapeutic use; D015433:Glomerulonephritis, Membranous / Q000188:drug therapy; D006801:Humans; D008517:Phytotherapy / Q000009:adverse effects / Q000379:methods*; D029757:Tripterygium / Q000737:chemistry*
D004338:Drug Combinations; D004365:Drugs, Chinese Herbal