title: Moderate consumption of olive oil by healthy European men reduces systolic blood pressure in non-Mediterranean participants.
abstract: We evaluated the effects of a moderate consumption of olive oil on lipid profile, BMI, and blood pressure (BP) in a group of 160 healthy men from non-Mediterranean regions [Northern Europe (n = 50; Finland and Denmark) and Central Europe (n = 60; Germany)] and Mediterranean regions [Southern Europe (n = 45; Italy and Spain)]. The study was a randomized, cross-over trial with 3 intervention periods of 3 wk and 2 wash-out periods of 2 wk. At the intervention periods, 3 similar olive oils (25 mL/d), differing only in their phenolic concentration, were administered to the healthy volunteers. Plasma oleic acid levels increased 2-3% (P < 0.05) in men from populations with lower habitual olive oil intakes (Northern and Central Europe). General linear models showed that the administration of the sequence of the 3 olive oils was responsible for a 3% decrease in systolic BP (SBP) (P < 0.05), but not in diastolic BP, in the non-Mediterranean subjects. Multivariate analysis indicated that the lipid profile did not change in either Mediterranean or non-Mediterranean men due to the olive oil intervention. The results of this study suggest that a moderate consumption of olive oil may be used as an effective tool to reduce SBP of healthy men who do not typically consume a Mediterranean diet. However, additional longer trials are necessary for confirmation.
authors.affiliation: Department of Nutrition and Food Science, Centre of Reference in Technology of Food, Faculty of Pharmacy, University of Barcelona, s/n E-08028 Barcelona, Spain.
authors.forename: Isabel
authors.initials: I
authors.lastname: Bondia-Pons
authors.forename: Helmut
authors.initials: H
authors.lastname: Schröder
authors.forename: María-Isabel
authors.initials: MI
authors.lastname: Covas
authors.forename: Ana I
authors.initials: AI
authors.lastname: Castellote
authors.forename: Jari
authors.initials: J
authors.lastname: Kaikkonen
authors.forename: Henrik E
authors.initials: HE
authors.lastname: Poulsen
authors.forename: Antonio V
authors.initials: AV
authors.lastname: Gaddi
authors.forename: Anja
authors.initials: A
authors.lastname: Machowetz
authors.forename: Holger
authors.initials: H
authors.lastname: Kiesewetter
authors.forename: M Carmen
authors.initials: MC
authors.lastname: López-Sabater
mesh_terms: D000328:Adult; D001794:Blood Pressure; D015992:Body Mass Index; D018592:Cross-Over Studies; D005060:Europe; D005843:Geography; D006801:Humans; D008297:Male; D000069463:Olive Oil; D010938:Plant Oils / Q000494:pharmacology*; D012016:Reference Values; D013599:Systole
chemical_list: D000069463:Olive Oil; D010938:Plant Oils