title: An enhancing pituitary lesion in a young woman: a diagnostic dilemma.
abstract: Wegener's granulomatosis is a systemic small-vessel vasculitis predominantly involving the upper airways, lungs and kidneys. Central nervous system involvement is known to occur in 10% of cases, manifesting as diffuse meningeal involvement and cerebral granulomatous lesions, but isolated involvement of the pituitary is extremely rare. We describe a case of isolated pituitary involvement with abscess formation secondary to Wegener's granulomatosis in a 21-year-old woman. To the best of our knowledge this is the first reported case of pituitary abscess formation secondary to Wegener's granulomatosis.
authors.affiliation: Department of Neurosurgery, Hope Hospital, 65 Vancouver Quay, Salford Quays Salford, Manchester, Lancashire M50 3TU, UK. waz79@hotmail.com
authors.forename: Wasiq
authors.initials: W
authors.lastname: Thiryayi
authors.forename: Marcia Hugh
authors.initials: MH
authors.lastname: Donaldson
authors.forename: David
authors.initials: D
authors.lastname: Border
authors.forename: Atul
authors.initials: A
authors.lastname: Tyagi
mesh_terms: D000328:Adult; D001922:Brain Abscess / Q000209:etiology / Q000473:pathology; D005260:Female; D014890:Granulomatosis with Polyangiitis / Q000150:complications* / Q000473:pathology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D010900:Pituitary Diseases / Q000209:etiology* / Q000473:pathology*; D010902:Pituitary Gland / Q000473:pathology