title: X-ray single-crystal analysis of (-)-(S)-equol isolated from rat's feces.
abstract: The biological effects of soy isoflavones have attracted considerable interest in recent years, leading to numerous studies on dietary intake and epidemiology. (-)-(S)-equol (3) is a metabolite produced in vivo from the isoflavone daidzein, a kind of soy phytoestrogen, by the action of gut microflora. It has higher biological activity than its precursor. Here, we wish to report the isolation and first X-ray crystal structure of 3 from the feces of rats fed a soy-isoflavone-containing diet.
authors.affiliation: Department of Chemistry of Natural Drugs, School of Pharmacy, Fudan University, Shanghai 200032, PR China. lianggl72@shmu.edu.cn
authors.forename: Gaolin
authors.initials: G
authors.lastname: Liang
authors.forename: Tong
authors.initials: T
authors.lastname: Zhang
authors.forename: Jingmei
authors.initials: J
authors.lastname: Wang
authors.forename: Buyun
authors.initials: B
authors.lastname: Chen
authors.forename: Kejun
authors.initials: K
authors.lastname: Cheng
authors.forename: Changqi
authors.initials: C
authors.lastname: Hu
mesh_terms: D000818:Animals; D018360:Crystallography, X-Ray; D060754:Equol; D005243:Feces / Q000737:chemistry*; D005260:Female; D007529:Isoflavones / Q000737:chemistry*; D008958:Models, Molecular; D015394:Molecular Structure; D051381:Rats; D017207:Rats, Sprague-Dawley
chemical_list: C007610:4',7-dihydroxy-3,4-dihydroisoflavone; D007529:Isoflavones; D060754:Equol