title: Work stress, mental health and antidepressant medication findings from the Health 2000 Study.
abstract: BACKGROUND
  Population-based studies on the association between work stress and mental disorders are scarce, and it is not known whether work stress predicts mental disorders requiring treatment.
  
  
  OBJECTIVE
  To examine the associations of work stress with DSM-IV mental disorders and subsequent antidepressant medication.
  
  
  METHODS
  3366 participants from a representative sample of the Finnish working population responded to a survey (The Health 2000 Study). 12-month prevalence of depressive or anxiety disorders was examined with the Composite International Diagnostic Interview. Data on antidepressant prescriptions with a 3-year follow-up period were collected from a nationwide register of Social Insurance Institution.
  
  
  RESULTS
  In men and women, high job demands, low job control and high job strain were associated with 12-month prevalence of depressive or anxiety disorders. After adjustment for lifetime and baseline mental disorders, men with high job demands and high job strain had increased risk of future antidepressant medication.
  
  
  CONCLUSIONS
  Work stress is associated with mental disorders among both sexes and among men it is a risk factor for mental disorders treated with antidepressant medication.
authors.affiliation: Finnish Institute of Occupational Health, Topeliuksenkatu 41 aA, FIN-00250 Helsinki, Finland. marianna.virtanen@ttl.fi
authors.forename: Marianna
authors.initials: M
authors.lastname: Virtanen
authors.forename: Teija
authors.initials: T
authors.lastname: Honkonen
authors.forename: Mika
authors.initials: M
authors.lastname: Kivimäki
authors.forename: Kirsi
authors.initials: K
authors.lastname: Ahola
authors.forename: Jussi
authors.initials: J
authors.lastname: Vahtera
authors.forename: Arpo
authors.initials: A
authors.lastname: Aromaa
authors.forename: Jouko
authors.initials: J
authors.lastname: Lönnqvist
mesh_terms: D000328:Adult; D000928:Antidepressive Agents / Q000627:therapeutic use*; D001008:Anxiety Disorders / Q000175:diagnosis / Q000188:drug therapy* / Q000453:epidemiology*; D003710:Demography; D003866:Depressive Disorder / Q000175:diagnosis / Q000188:drug therapy* / Q000453:epidemiology*; D039721:Diagnostic and Statistical Manual of Mental Disorders; D004358:Drug Therapy / Q000706:statistics & numerical data; D005260:Female; D006801:Humans; D007588:Job Satisfaction; D008297:Male; D008875:Middle Aged; D011159:Population Surveillance; D015995:Prevalence; D013315:Stress, Psychological / Q000453:epidemiology* / Q000523:psychology*; D017132:Workplace / Q000523:psychology* / Q000706:statistics & numerical data*
chemical_list: D000928:Antidepressive Agents