[Medication of the month. Duloxetine (Cymbalta)].
Duloxetine (Cymbalta is an antidepressant of the class of serotonin noradrenaline reuptake inhibitors. The efficacy of duloxetine 60 mg/day has been well demonstrated in the acute and long term treatment of major depression. The level of effectiveness of duloxetine is particularly high and associated with a shorter latency of action. Duloxetine also exhibits antinociceptive properties independently of the antidepressant effect. The side-effect profile of duloxetine is particularly good and similar to selective serotonin reuptake inhibitors with mainly nausea. In total, duloxetine represents a real progress in the pharmacological treatment of major depression.
Pitchot
W
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Université de Liège, Service de Psychiatrie et de Psychologie Médicale, CHU Sart Tilman, Liège, Belgique.
D000928:Antidepressive Agents / Q000494:pharmacology*; D003863:Depression / Q000188:drug therapy; D000068736:Duloxetine Hydrochloride; D006801:Humans; D013876:Thiophenes / Q000494:pharmacology*
D000928:Antidepressive Agents; D013876:Thiophenes; D000068736:Duloxetine Hydrochloride