Sonohysterography versus transvaginal sonography for screening of patients with abnormal uterine bleeding.
OBJECTIVE
To compare the accuracy of saline infusion sonohysterography (SIS) with transvaginal sonography (TVS) for the screening of causes of abnormal uterine bleeding (AUB) in out-patients.


METHODS
81 patients with AUB were studied. All cases who were examined with TVS, were further investigated with SIS using saline as contrast medium, finally hysteroscopy was used as the gold standard.


RESULTS
TVS had sensitivity of 72%, specificity of 92%, positive predictive value of 94% and negative predictive value of 65%, while SIS had sensitivity of 94.1%, specificity of 95%, positive predictive value of 96% and negative predictive value of 90%. TVS had kappa measure of agreement of 0.60 while 0.86 was reported for SIS.


CONCLUSIONS
In this study SIS was more sensitive and specific in diagnosing polyp, myoma and adenomyosis with high positive and negative predictive value. Furthermore, results obtained by SIS demonstrate more agreement with that obtained by hysteroscopy than TVS.
Alborzi
S
S
Department of Obstetrics and Gynecology, Shiraz University of Medical Sciences, Shiraz, Iran. alborzis@sums.ac.ir
Parsanezhad
M E
ME
Mahmoodian
N
N
Alborzi
S
S
Alborzi
M
M
D004715:Endometriosis / Q000000981:diagnostic imaging; D019160:Endosonography / Q000379:methods*; D005260:Female; D006801:Humans; D007889:Leiomyoma / Q000000981:diagnostic imaging*; D008796:Metrorrhagia / Q000000981:diagnostic imaging*; D012680:Sensitivity and Specificity; D012965:Sodium Chloride / Q000008:administration & dosage; D014594:Uterine Neoplasms / Q000000981:diagnostic imaging*; D014599:Uterus / Q000000981:diagnostic imaging*
D012965:Sodium Chloride