title: Reduction of mitral valve regurgitation caused by acute papillary muscle ischemia.
abstract: BACKGROUND
  A 67-year-old man was admitted to a coronary care unit for non-ST-segment elevation myocardial infarction with complicating acute heart failure. Severe mitral regurgitation was detected by echocardiography at presentation. Repeat echocardiography carried out during another ischemic episode revealed a marked reduction in the patient's mitral regurgitation that was related to decreased apical traction of the valve leaflets.
  
  
  METHODS
  Physical examination, electrocardiography, laboratory tests, coronary angiography, chest radiography, echocardiography.
  
  
  METHODS
  Mitral regurgitation associated with acute coronary syndrome.
  
  
  RESULTS
  Early revascularization by percutaneous coronary intervention, supported by pharmacological therapy to decrease left ventricular filling pressure.
authors.affiliation: Department of Cardiothoracic and Vascular Diseases, University Vita-Salute, San Raffaele Scientific Institute, Via Olgettina 58, 20132 Milan, Italy. magnoni.marco@hsr.it
authors.forename: Marco
authors.initials: M
authors.lastname: Magnoni
authors.forename: Stefano
authors.initials: S
authors.lastname: Coli
authors.forename: Giovanni
authors.initials: G
authors.lastname: La Canna
authors.forename: Carlo
authors.initials: C
authors.lastname: Meloni
authors.forename: Domenico
authors.initials: D
authors.lastname: Cianflone
authors.forename: Attilio
authors.initials: A
authors.lastname: Maseri
mesh_terms: D000208:Acute Disease; D000368:Aged; D015906:Angioplasty, Balloon, Coronary; D002317:Cardiovascular Agents / Q000627:therapeutic use; D018618:Echocardiography, Doppler, Color; D006801:Humans; D008297:Male; D008943:Mitral Valve / Q000000981:diagnostic imaging / Q000503:physiopathology; D008944:Mitral Valve Insufficiency / Q000175:diagnosis* / Q000209:etiology* / Q000503:physiopathology / Q000628:therapy; D009200:Myocardial Contraction; D017202:Myocardial Ischemia / Q000150:complications* / Q000175:diagnosis* / Q000503:physiopathology / Q000628:therapy; D010210:Papillary Muscles / Q000000981:diagnostic imaging / Q000503:physiopathology*; D016277:Ventricular Function, Left / Q000187:drug effects
chemical_list: D002317:Cardiovascular Agents