title: MISSION!: optimization of acute and chronic care for patients with acute myocardial infarction.
abstract: BACKGROUND
  Guideline implementation programs for patients with acute myocardial infarction (AMI) enhance adherence to evidence-based medicine (EBM) and improve clinical outcome. Although undertreatment of patients with AMI is well recognized in both acute and chronic phases of care, most implementation programs focus on acute and secondary prevention strategies during the index hospitalization phase only.
  
  
  OBJECTIVE
  Implementation of an all-phase integrated AMI care program maximizes EBM in daily practice and improves the care for patients with AMI.
  
  
  OBJECTIVE
  The objective of this study is to assess the effects of the MISSION! program on adherence to EBM for patients with AMI by the use of performance indicators.
  
  
  METHODS
  The MISSION! protocol is based on the most recent American College of Cardiology/American Heart Association and European Society of Cardiology guidelines for patients with AMI. It contains a prehospital, inhospital, and outpatient clinical framework for decision making and treatment, up to 1 year after the index event. MISSION! concentrates on rapid AMI diagnosis and early reperfusion, followed by active lifestyle improvement and structured medical therapy. Because MISSION! covers both acute and chronic AMI phase, this design implies an intensive multidisciplinary collaboration among all regional health care providers.
  
  
  CONCLUSIONS
  Continuum of care for patients with AMI is warranted to take full advantage of EBM in day-to-day practice. This manuscript describes the rationale, design, and preliminary results of MISSION!, an all-phase integrated AMI care program.
authors.affiliation: Leiden University Medical Center, Leiden, The Netherlands.
authors.forename: Su-San
authors.initials: SS
authors.lastname: Liem
authors.forename: Barend L
authors.initials: BL
authors.lastname: van der Hoeven
authors.forename: Pranobe V
authors.initials: PV
authors.lastname: Oemrawsingh
authors.forename: Jeroen J
authors.initials: JJ
authors.lastname: Bax
authors.forename: Johanna G
authors.initials: JG
authors.lastname: van der Bom
authors.forename: Jan
authors.initials: J
authors.lastname: Bosch
authors.forename: Eric P
authors.initials: EP
authors.lastname: Viergever
authors.forename: Cees
authors.initials: C
authors.lastname: van Rees
authors.forename: Iman
authors.initials: I
authors.lastname: Padmos
authors.forename: Meredith I
authors.initials: MI
authors.lastname: Sedney
authors.forename: Henk J
authors.initials: HJ
authors.lastname: van Exel
authors.forename: Harriette F
authors.initials: HF
authors.lastname: Verwey
authors.forename: Douwe E
authors.initials: DE
authors.lastname: Atsma
authors.forename: Enno T
authors.initials: ET
authors.lastname: van der Velde
authors.forename: J Wouter
authors.initials: JW
authors.lastname: Jukema
authors.forename: Ernst E
authors.initials: EE
authors.lastname: van der Wall
authors.forename: Martin J
authors.initials: MJ
authors.lastname: Schalij
mesh_terms: D000208:Acute Disease; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002908:Chronic Disease; D002985:Clinical Protocols; D003191:Comprehensive Health Care / Q000592:standards*; D003266:Continuity of Patient Care; D003299:Cooperative Behavior; D019317:Evidence-Based Medicine; D005260:Female; D019983:Guideline Adherence / Q000458:organization & administration*; D015438:Health Behavior; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000534:rehabilitation / Q000628:therapy*; D009426:Netherlands; D010348:Patient Care Team / Q000592:standards; D017410:Practice Guidelines as Topic; D019984:Quality Indicators, Health Care; D015912:Thrombolytic Therapy; D014218:Triage