title: Pregnancy and pregnancy outcome among women with inflammatory skin diseases.
abstract: OBJECTIVE
  The effect of inflammatory skin diseases on pregnancy has been incompletely characterized. We sought to estimate the incidence of pregnancy and pregnancy outcomes among women with inflammatory skin diseases.
  
  
  METHODS
  Cohort study of women with atopic dermatitis (AD), psoriasis, other inflammatory skin diseases, and comparison group, followed for pregnancies and pregnancy outcomes.
  
  
  RESULTS
  There were 3,131 pregnancies among 64,773 woman-years (4.8/100) in women with skin diseases, and 2,592 pregnancies among 59,826 woman-years (4.3/100) in the comparison group. The age-standardized incidence of pregnancy was similar to the comparison group [rate ratio (RR) = 1.2, 95% confidence interval (CI) 1.0-1.4 for AD, RR = 1.1, 95% CI 1.0-1.2 for psoriasis, and RR = 1.1, 95% CI 1.0-1.1 for other]. Spontaneous abortion was also similar to the comparison group (RR = 1.2 for AD, 95% CI 1.0-1.4, RR = 1.1, 95% CI 1.0-1.2 for psoriasis, and RR = 1.1, 95% CI 1.0-1.1 for other).
  
  
  CONCLUSIONS
  Our results suggest little effect of skin disease on incidence or outcome of pregnancy.
authors.affiliation: Ingenix Epidemiology, Auburndale, MA, USA. jseeger@epidemiology.com
authors.forename: John D
authors.initials: JD
authors.lastname: Seeger
authors.forename: Lee L
authors.initials: LL
authors.lastname: Lanza
authors.forename: William A
authors.initials: WA
authors.lastname: West
authors.forename: Carlos
authors.initials: C
authors.lastname: Fernandez
authors.forename: Elena
authors.initials: E
authors.lastname: Rivero
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D016001:Confidence Intervals; D003876:Dermatitis, Atopic / Q000453:epidemiology*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D008875:Middle Aged; D011247:Pregnancy; D011248:Pregnancy Complications; D011256:Pregnancy Outcome / Q000453:epidemiology*; D011565:Psoriasis / Q000453:epidemiology*; D012189:Retrospective Studies; D014481:United States / Q000453:epidemiology