title: Cultivation-independent analysis of changes in bacterial vaginosis flora following metronidazole treatment.
abstract: PCR was used to survey bacterial vaginosis flora before and after metronidazole treatment. The species composition for pretreatment patients was variable. Lactobacillus iners was prominent in all patients posttreatment. Atopobium vaginae concentrations were highest for patients who failed or responded incompletely to treatment and lowest for patients who were cured.
authors.affiliation: Department of Pediatrics, Louisiana State University Health Sciences Center, New, Orleans, Louisiana 70112, USA. mferris@chnola-research.org
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Ferris
authors.forename: Johana
authors.initials: J
authors.lastname: Norori
authors.forename: Marcela
authors.initials: M
authors.lastname: Zozaya-Hinchliffe
authors.forename: David H
authors.initials: DH
authors.lastname: Martin
mesh_terms: D039903:Actinobacteria / Q000235:genetics / Q000254:growth & development / Q000302:isolation & purification*; D000890:Anti-Infective Agents / Q000627:therapeutic use*; D004269:DNA, Bacterial / Q000032:analysis; D005260:Female; D006801:Humans; D007778:Lactobacillus / Q000235:genetics / Q000254:growth & development / Q000302:isolation & purification*; D008795:Metronidazole / Q000627:therapeutic use*; D016133:Polymerase Chain Reaction / Q000379:methods*; D016896:Treatment Outcome; D016585:Vaginosis, Bacterial / Q000188:drug therapy* / Q000382:microbiology*
chemical_list: D000890:Anti-Infective Agents; D004269:DNA, Bacterial; D008795:Metronidazole