Diffuse cutaneous leishmaniasis in an HIV-positive patient in western Africa.
A 36-year-old HIV1-positive woman presented with a 6-month history of a progressive papular and nodular eruption of the face and subsequent extensive spread to the rest of the skin. The diagnosis of diffuse cutaneous leishmaniasis was established by direct examination and skin biopsy. This atypical form had a dramatic improvement after a 21-day treatment with meglumine antimoniate. This clinical form may be confused with other endemic diseases in western Africa, especially leprosy.
Niamba
Pascal
P
Dermatology Unit, University Hospital, Ouagadougou, Burkina Faso. niamba_pascal@yahoo.com
Goumbri-Lompo
Olga
O
Traoré
Adama
A
Barro-Traoré
Fatou
F
Soudré
Robert T
RT
D000354:Africa, Western; D000981:Antiprotozoal Agents / Q000008:administration & dosage / Q000627:therapeutic use; D003937:Diagnosis, Differential; D005148:Facial Dermatoses / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D005260:Female; D015658:HIV Infections; D006801:Humans; D007273:Injections, Intramuscular; D016774:Leishmaniasis, Diffuse Cutaneous / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D008536:Meglumine / Q000008:administration & dosage / Q000627:therapeutic use; D000077485:Meglumine Antimoniate; D008875:Middle Aged; D009942:Organometallic Compounds / Q000008:administration & dosage / Q000627:therapeutic use
D000981:Antiprotozoal Agents; D009942:Organometallic Compounds; D008536:Meglumine; D000077485:Meglumine Antimoniate