Necrotizing crescentic glomerulonephritis--a conditional knockout model discloses new therapeutic challenges.
Rastaldi
Maria Pia
MP
Renal Immunopathology Laboratory, Fondazione D'Amico per la Ricerca sulle Malattie Renali, c/o San Carlo Hospital, via Pio II, 3 20153 Milan, Italy. mp.rastaldi@fastwebnet.it
D000818:Animals; D054377:Chemokine CXCL12; D019743:Chemokines, CXC / Q000235:genetics / Q000378:metabolism; D004195:Disease Models, Animal; D005921:Glomerulonephritis / Q000235:genetics* / Q000378:metabolism / Q000473:pathology; D006801:Humans; D051795:Hypoxia-Inducible Factor 1, alpha Subunit / Q000235:genetics / Q000378:metabolism; D007673:Kidney Cortex Necrosis / Q000235:genetics* / Q000378:metabolism / Q000473:pathology; D051379:Mice; D018345:Mice, Knockout; D050199:Podocytes / Q000378:metabolism / Q000473:pathology; D019718:Receptors, CXCR4 / Q000235:genetics / Q000378:metabolism; D051794:Von Hippel-Lindau Tumor Suppressor Protein / Q000235:genetics / Q000378:metabolism
C515255:CXCL12 protein, human; C514936:CXCR4 protein, mouse; D054377:Chemokine CXCL12; D019743:Chemokines, CXC; C515256:Cxcl12 protein, mouse; C497443:Hif1a protein, mouse; D051795:Hypoxia-Inducible Factor 1, alpha Subunit; D019718:Receptors, CXCR4; D051794:Von Hippel-Lindau Tumor Suppressor Protein; C494469:VHL protein, mouse