title: [Effects of annao tablet on S100B and NPY of cortex in chronic epilepsy rats].
abstract: OBJECTIVE
  To study the effects of Annao tablet (main component is beta-asarone) on S100B and NPY of cortex in chronic epilepsy rats.
  
  
  METHODS
  The remedy was administered orally. The effects were observed in convulsion model induced by PG, then S100B protein and NPY of cortex were determined.
  
  
  RESULTS
  Annao tablet could depress the epileptic degree, postpone spasm latent period and reduce the wet dog sample (WDS) times. The remedy could decline S100B and NPY of cortex in chronic epilepsy rats.
  
  
  CONCLUSIONS
  Annao tablet has obvious antiepileptic effects and can reduce the nerve cell damage induced by epilepsy.
authors.affiliation: Guangzhou University of Traditional Chinese Medicine, Guangzhou 510405, China.
authors.forename: Ruo-Ming
authors.initials: RM
authors.lastname: Fang
authors.forename: Geng-Li
authors.initials: GL
authors.lastname: Fang
authors.forename: Yong-Qi
authors.initials: YQ
authors.lastname: Fang
mesh_terms: D029023:Acorus / Q000737:chemistry; D000081248:Allylbenzene Derivatives; D000818:Animals; D000840:Anisoles / Q000008:administration & dosage / Q000302:isolation & purification / Q000494:pharmacology*; D000927:Anticonvulsants / Q000008:administration & dosage / Q000302:isolation & purification / Q000494:pharmacology; D002540:Cerebral Cortex / Q000378:metabolism*; D004337:Drug Carriers; D004827:Epilepsy / Q000378:metabolism* / Q000503:physiopathology; D005260:Female; D008297:Male; D009478:Neuropeptide Y / Q000378:metabolism*; D010946:Plants, Medicinal / Q000737:chemistry; D051381:Rats; D017207:Rats, Sprague-Dawley; D009418:S100 Proteins / Q000378:metabolism*; D013607:Tablets; D047392:beta-Cyclodextrins
chemical_list: D000081248:Allylbenzene Derivatives; D000840:Anisoles; D000927:Anticonvulsants; D004337:Drug Carriers; D009478:Neuropeptide Y; D009418:S100 Proteins; D013607:Tablets; C012195:asarone; D047392:beta-Cyclodextrins