Supernumerary minute ring chromosome 14 in a man with primary infertility and left varicocele.
OBJECTIVE
To describe a case of supernumerary minute ring chromosome (SMRC) in an infertile man, with the concurrent finding of a left varicocele.


METHODS
Case report.


METHODS
Urologic infertility clinic in a university hospital.


METHODS
Male patient presenting with primary infertility.


METHODS
Karyotyping, genetic counseling, and microsurgical left varicocelectomy.


METHODS
Sperm concentration and motility, chromosomal number and structure.


RESULTS
Fluorescence in situ hybridization revealing SMRC 14. Sperm concentration and motility improved after left varicocele repair.


CONCLUSIONS
A karyotype should be included in the evaluation of severe oligospermia. Although SMRC 14 may be associated with fertility problems, repair of a coexisting varicocele should be considered in these patients.
Stahl
Brandon C
BC
Department of Urology, University of Iowa, Iowa City, Iowa 52242-1089, USA.
Patil
Shivanand R
SR
Syrop
Craig H
CH
Sparks
Amy E T
AE
Wald
Moshe
M
D000328:Adult; D002883:Chromosomes, Human, Pair 14; D006801:Humans; D007248:Infertility, Male / Q000175:diagnosis* / Q000235:genetics* / Q000601:surgery; D008297:Male; D012303:Ring Chromosomes; D014646:Varicocele / Q000175:diagnosis* / Q000235:genetics* / Q000601:surgery