title: Pre-operative tumor assessment of patients with gastric cancer based on virtual endoscopy using multidetector-row computer tomography.
abstract: BACKGROUND
  The possibilities and limitations of computer tomography (CT) examination for detecting primary gastric cancer tumors have been poorly understood. The aim of the present study was to evaluate the pre-operative assessment of gastric cancer tumors using 32-multidetector row-CT.
  
  
  METHODS
  A prospective study of the pre-operative assessment of gastric cancer tumors using 32-multidetector row-CT was carried out. Seventy-four patients with adenocarcinoma of the stomach (T1 tumors, 38; T2 and T3 tumors, 36) underwent abdominal CTs to assess the feasibility of using MD-CT to assess primary lesions.
  
  
  RESULTS
  In 35 (47%) out of the 74 patients, the primary lesions could be detected on 2-D images obtained by CT. In these patients, virtual endoscopic images of these tumors could be created. Twenty-seven advanced cancer tumors (75%) were assessed based on 2-D CT images and 27 larger tumors (>40 mm) (69%) were assessed based on 2-D CT images. Significant differences were found with respect to depth of tumor (p<0.0001) and tumor size (p<0.0001) between tumors that could or could not be assessed on MD-CT.
  
  
  CONCLUSIONS
  The findings of the present study show that CT assessment of tumors is feasible in patients with advanced gastric cancer. Future studies are required to fully explore the ability of MD-CT to assess tumor volume in advanced gastric cancer cases and to determine the optimum application of this approach.
authors.affiliation: Department of Surgery, School of Medicine, Kitasato University, 1-15-1 Kitasato, Sagamihara-shi, Japan. kiku@kitasato-u.ac.jp
authors.forename: Shiro
authors.initials: S
authors.lastname: Kikuchi
authors.forename: Nobue
authors.initials: N
authors.lastname: Futawatari
authors.forename: Shinichi
authors.initials: S
authors.lastname: Sakuramoto
authors.forename: Masahiko
authors.initials: M
authors.lastname: Watanabe
authors.forename: Katsumi
authors.initials: K
authors.lastname: Kubota
authors.forename: Mayumi
authors.initials: M
authors.lastname: Sasaki
authors.forename: Koichiro
authors.initials: K
authors.lastname: Murata
authors.forename: Mitsuhiro
authors.initials: M
authors.lastname: Kida
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis* / Q000473:pathology; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016099:Endoscopy, Gastrointestinal / Q000379:methods; D005260:Female; D006801:Humans; D021621:Imaging, Three-Dimensional / Q000379:methods; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D011300:Preoperative Care; D011446:Prospective Studies; D013274:Stomach Neoplasms / Q000175:diagnosis* / Q000473:pathology; D014057:Tomography, X-Ray Computed / Q000379:methods*