title: [Case of severe ulcerative colitis successfully treated with intravenous cyclosporine without high dose corticosteroid].
abstract: A 44-year-old women developed marked myopathy one year earlier, when she was treated with intravenous prednisolone for acute severe exacerbation of ulcerative colitis. When she was admitted to our hospital for another severe exacerbation, intravenous cyclosporine A was administered as monotherapy because she could not tolerate corticosteroid. The treatment was successful and she obtained complete remission. Cyclosporine A monotherapy is considered to be a valuable alternative to proctocolectomy for severe ulcerative colitis patients who cannot tolerate corticosteroid.
authors.affiliation: Department of Gastroenterology and Hepatology, Tokyo Medical and Dental University, Japan.
authors.forename: Daisuke
authors.initials: D
authors.lastname: Kubota
authors.forename: Takanori
authors.initials: T
authors.lastname: Kanai
authors.forename: Fumiro
authors.initials: F
authors.lastname: Yui
authors.forename: Tomoko
authors.initials: T
authors.lastname: Matsumoto
authors.forename: Takahiro
authors.initials: T
authors.lastname: Kawamura
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Itsui
authors.forename: Eriko
authors.initials: E
authors.lastname: Okada
authors.forename: Seishin
authors.initials: S
authors.lastname: Chin
authors.forename: Shinya
authors.initials: S
authors.lastname: Ooka
authors.forename: Masakazu
authors.initials: M
authors.lastname: Nagahori
authors.forename: Kiichiro
authors.initials: K
authors.lastname: Tsuchiya
authors.forename: Akihiro
authors.initials: A
authors.lastname: Araki
authors.forename: Naoya
authors.initials: N
authors.lastname: Sakamoto
authors.forename: Tatsuya
authors.initials: T
authors.lastname: Miyata
authors.forename: Mamoru
authors.initials: M
authors.lastname: Watanabe
mesh_terms: D000328:Adult; D003093:Colitis, Ulcerative / Q000188:drug therapy*; D016572:Cyclosporine / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage*; D007262:Infusions, Intravenous; D015122:Mercaptopurine / Q000008:administration & dosage; D011239:Prednisolone / Q000008:administration & dosage* / Q000009:adverse effects*; D016896:Treatment Outcome
chemical_list: D007166:Immunosuppressive Agents; D016572:Cyclosporine; D011239:Prednisolone; D015122:Mercaptopurine