title: Synthesis of potent bicyclic bisarylimidazole c-Jun N-terminal kinase inhibitors by catalytic C-H bond activation.
authors.affiliation: Department of Chemistry, University of California, and Division of Chemical Sciences, Lawrence Berkeley National Laboratory, Berkeley, California 94729, USA.
authors.forename: Jason C
authors.initials: JC
authors.lastname: Rech
authors.forename: Michihisa
authors.initials: M
authors.lastname: Yato
authors.forename: Derek
authors.initials: D
authors.lastname: Duckett
authors.forename: Brian
authors.initials: B
authors.lastname: Ember
authors.forename: Philip V
authors.initials: PV
authors.lastname: LoGrasso
authors.forename: Robert G
authors.initials: RG
authors.lastname: Bergman
authors.forename: Jonathan A
authors.initials: JA
authors.lastname: Ellman
mesh_terms: D001665:Binding Sites; D019086:Bridged Bicyclo Compounds, Heterocyclic / Q000138:chemical synthesis* / Q000494:pharmacology; D004791:Enzyme Inhibitors / Q000138:chemical synthesis* / Q000494:pharmacology; D007093:Imidazoles / Q000138:chemical synthesis* / Q000494:pharmacology; D048031:JNK Mitogen-Activated Protein Kinases / Q000037:antagonists & inhibitors; D008956:Models, Chemical
chemical_list: D019086:Bridged Bicyclo Compounds, Heterocyclic; D004791:Enzyme Inhibitors; D007093:Imidazoles; D048031:JNK Mitogen-Activated Protein Kinases