title: [Amyotrophic lateral sclerosis in Baranya county, Hungary].
abstract: Amyotrophic lateral sclerosis is a progressive neurodegenerative disease resulting in loss of upper and lower motoneurons. Here we analyzed the clinical and epidemiological data of 202 ALS patients admitted to our department between 1950 and 2004. Risk and protective factors influencing onset and progression of the disease were examined. We also analyzed the relationship between first clinical symptoms/signs and prognosis of the disease. Our data suggest the importance of toxic factors in the initiation of the disease and the effect of clinical phenotype on the progression of ALS.
authors.affiliation: Pécsi Tudományegyetem, Altalános Orvostudományi Kar, Neurológiai Klinika, Pécs. hajnalka.merkli@aok.pte.hu
authors.forename: Hainalka
authors.initials: H
authors.lastname: Merkli
authors.forename: Ferenc
authors.initials: F
authors.lastname: Nagy
authors.forename: Endre
authors.initials: E
authors.lastname: Pál
authors.forename: István
authors.initials: I
authors.lastname: Gáti
authors.forename: Norbert
authors.initials: N
authors.lastname: Kovács
authors.forename: Sámuel
authors.initials: S
authors.lastname: Komoly
authors.forename: Zsolt
authors.initials: Z
authors.lastname: Illés
mesh_terms: D000328:Adult; D017677:Age Distribution; D000368:Aged; D000690:Amyotrophic Lateral Sclerosis / Q000453:epidemiology* / Q000209:etiology / Q000401:mortality; D005260:Female; D006801:Humans; D006814:Hungary / Q000453:epidemiology; D015994:Incidence; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D017678:Sex Distribution