title: [Antimicrobial peptides].
abstract: For many years, attention has been focused on adaptive immunity as the main antimicrobial defense system. The discovery of antimicrobial peptides turned this point of view. In general, these peptides act on microorganisms directly by disrupting the structure of the microbial cytoplasmatic membranes and indirectly acting on immune system. This review provides an overview of some natural antimicrobial peptides and probability of their clinical usage.
authors.affiliation: Z Katedry i Zakładu Mikrobiologii Lekarskiej Slaskiej Akademii Medycznej, Katowicach.
authors.forename: Barbara E
authors.initials: BE
authors.lastname: Wiechuła
authors.forename: Jerzy P
authors.initials: JP
authors.lastname: Tustanowski
authors.forename: Gayane
authors.initials: G
authors.lastname: Martirosian
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000276:immunology* / Q000494:pharmacology*; D000890:Anti-Infective Agents / Q000494:pharmacology; D023181:Antimicrobial Cationic Peptides / Q000276:immunology* / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects; D001424:Bacterial Infections / Q000188:drug therapy; D054804:Cathelicidins; D002417:Cattle; D023082:Defensins / Q000145:classification / Q000276:immunology / Q000494:pharmacology; D005658:Fungi / Q000187:drug effects; D006801:Humans; D007110:Immunity, Active / Q000276:immunology
chemical_list: D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D023181:Antimicrobial Cationic Peptides; D054804:Cathelicidins; D023082:Defensins