Secondary breast angiosarcoma: lethal response to anti-angiogenic therapy with paclitaxel chemotherapy. A case report.
Angiosarcoma of the breast is a malignant tumour of vascular endothelial cells. It is a rare and difficult tumour to treat. The authors report a case of cutaneous radiation-associated angiosarcoma treated with paclitaxel chemotherapy. A few days after drug administration, bleeding of skin lesions was observed and the patient died.
Tomasello
Laura
L
Academic Department of Medical Oncology, National Cancer Research Institute, Genoa, Italy. lauratomasello@hotmail.com
Gardin
Giovanni
G
Boccardo
Francesco
F
D000369:Aged, 80 and over; D001943:Breast Neoplasms / Q000139:chemically induced* / Q000188:drug therapy / Q000473:pathology; D018270:Carcinoma, Ductal, Breast / Q000188:drug therapy / Q000473:pathology; D005260:Female; D006394:Hemangiosarcoma / Q000139:chemically induced* / Q000473:pathology; D006801:Humans; D016609:Neoplasms, Second Primary / Q000139:chemically induced* / Q000473:pathology; D017239:Paclitaxel / Q000009:adverse effects* / Q000627:therapeutic use
D017239:Paclitaxel