title: Abdominal aortic aneurysm repair and colonic infarction: a risk factor appraisal.
abstract: OBJECTIVE
  Colonic infarction is a recognized complication of abdominal aortic aneurysm (AAA) surgery. The clinical difficulty in establishing the diagnosis combined with the patient's poor physiological status is usually associated with a fatal outcome. We assessed our experience with this problem to identify a possible risk factor profile for these patients.
  
  
  METHODS
  Patients records were identified from the operative logs, intensive care unit, Hospital Inpatient Enquiry system and vascular unit databases over a 6-year period.
  
  
  RESULTS
  A total of 405 patients underwent AAA repair during this period; 140 as emergency ruptures. Nine patients were identified from the databases with known colonic infarction (2.2%). One was a woman. The mean age was 70 years. Seven patients had emergency ruptures (5%). Twenty independent risk factors were analysed using univariate and multivariate logistic regression models. Significant risk factors identified by using a multivariate analysis included the nature of the presenting patient, preoperative hypotension, prolonged cross-clamp time, intra-operative ischaemia and postoperative acidosis. Confirmatory diagnosis was made by colonoscopy in eight patients. One patient survived following the salvage surgery. The mean duration of survival was 10.5 days. The overall mortality was 89% of patients.
  
  
  CONCLUSIONS
  In our unit infrarenal AAA repair has a 2.2% rate of colonic infarction. A definitive diagnosis is best made by colonoscopy. A risk factor profile for the development of colonic infarction may be constructed on the basis of specific clinical parameters. Earlier intervention on the basis of this profile may ultimately reduce the current excessive mortality.
authors.affiliation: Department of Vascular Surgery, St Vincent's University Hospital, Dublin, Ireland. paulcneary@msn.com
authors.forename: P
authors.initials: P
authors.lastname: Neary
authors.forename: C
authors.initials: C
authors.lastname: Hurson
authors.forename: D O
authors.initials: DO
authors.lastname: Briain
authors.forename: A
authors.initials: A
authors.lastname: Brabazon
authors.forename: D
authors.initials: D
authors.lastname: Mehigan
authors.forename: T V
authors.initials: TV
authors.lastname: Keaveny
authors.forename: S
authors.initials: S
authors.lastname: Sheehan
mesh_terms: D000368:Aged; D017544:Aortic Aneurysm, Abdominal / Q000601:surgery*; D016022:Case-Control Studies; D003106:Colon / Q000098:blood supply*; D003108:Colonic Diseases / Q000209:etiology*; D005260:Female; D006801:Humans; D007511:Ischemia / Q000209:etiology*; D016015:Logistic Models; D008297:Male; D011183:Postoperative Complications / Q000209:etiology*; D018570:Risk Assessment; D012307:Risk Factors; D018709:Statistics, Nonparametric