[Preparation and characterization of Mn-Zn ferrite oxygene nanoparticle for tumor thermotherapy].
With the sulfate as the materials and NaOH as precipitator, Mn(0.4)Zn(0.6)Fe2O4 nanoparticles were produced, which are proved to be spinel Mn-Zn ferrite analyzed by X-ray diffraction(XRD). Their shapes are approximately global examined by transmission electron microscopy(TEM) and their average diameter is 50 nm measured with image analysis-system. The Curie temperature was measured and in vitro heating test in a alternating magnetic field was carried out. The results show that the Curie temperature is 105. 407 degrees C, While its magnetic fluid could rise to 43 degrees C - 47 degrees C due to different concentration in a alternating magnetic field. The result provide theoretical and practical evidence to select an appropriate material and concentration for tumor
Jia
Xiupeng
X
School of Basic Medical Science, Southeast University, Nanjing 210009, China.
Zhang
Dongsheng
D
Zheng
Jie
J
Gu
Ning
N
Zhu
Weichang
W
Fan
Xiangshan
X
Jin
Liqiang
L
Wan
Meiling
M
Li
Qunhui
Q
D004574:Electromagnetic Fields; D005290:Ferric Compounds / Q000737:chemistry*; D006801:Humans; D006979:Hyperthermia, Induced / Q000295:instrumentation*; D017895:Manganese Compounds / Q000737:chemistry*; D053768:Metal Nanoparticles / Q000737:chemistry*; D046529:Microscopy, Electron, Transmission; D009369:Neoplasms / Q000628:therapy*; D014961:X-Ray Diffraction; D017967:Zinc Compounds / Q000737:chemistry*
D005290:Ferric Compounds; D017895:Manganese Compounds; D017967:Zinc Compounds; C039048:manganese-zinc ferrite