title: [Chemical constituents in root of Zanthoxylum nitidum].
abstract: OBJECTIVE
  To study the chemical constituents of Zanthoxylum nitidum.
  
  
  METHODS
  Column chromatography on Silica gel and Sephadex LH - 20, and recrystallization were applied for the isolation and purification of the constituents. The structures were elucidated on the basis of spectral analysis, chemical evidences and by comparison with the data reported in literature.
  
  
  RESULTS
  From the CHCl3 fraction and n-butanol fraction of the EtOH extract of the roots of Z. nitidum, 10 compounds were isolated and identified as 2, 4-dihydroxypyrimidine (1), syringic acid (2) , 2, 6-dimethoxy-1, 4-benzoquinone (3) , 4-hydroxybenzoic acid (4), ethylparaben (5), (Z)-3-(2, 3, 4-trimethoxyphenyl) acrylic acid (6), 5, 6, 7-trimethoxycoumarin (7), stigmast-9 (11) -en-3-ol (8), daucosterol (9), beta-sitosterol (10).
  
  
  CONCLUSIONS
  Compounds 1-9 were isolated and identified from the roots of Z. nitidum for the first time. Furthermore, we note here the first isolation of compound 6 as a natural product.
authors.affiliation: School of Pharmacy, Second Military Medical University, Shanghai 200433, China.
authors.forename: Jiang
authors.initials: J
authors.lastname: Hu
authors.forename: Wei-Dong
authors.initials: WD
authors.lastname: Zhang
authors.forename: Run-Hui
authors.initials: RH
authors.lastname: Liu
authors.forename: Chuan
authors.initials: C
authors.lastname: Zhang
authors.forename: Yun-Heng
authors.initials: YH
authors.lastname: Shen
authors.forename: Xi-Ke
authors.initials: XK
authors.lastname: Xu
authors.forename: Ming-Jin
authors.initials: MJ
authors.lastname: Liang
authors.forename: Hui-Liang
authors.initials: HL
authors.lastname: Li
mesh_terms: D000179:Acrylates / Q000737:chemistry / Q000302:isolation & purification*; D005707:Gallic Acid / Q000031:analogs & derivatives / Q000737:chemistry / Q000302:isolation & purification; D010226:Parabens / Q000737:chemistry; D018517:Plant Roots / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D032106:Zanthoxylum / Q000737:chemistry*
chemical_list: C524213:3-(2,3,4-trimethoxyphenyl)acrylic acid; D000179:Acrylates; D010226:Parabens; D005707:Gallic Acid; C001945:syringic acid; C038193:4-hydroxybenzoic acid