Effects of toxoplasma on human behavior.
Although latent infection with Toxoplasma gondii is among the most prevalent of human infections, it has been generally assumed that, except for congenital transmission, it is asymptomatic. The demonstration that latent Toxoplasma infections can alter behavior in rodents has led to a reconsideration of this assumption. When infected human adults were compared with uninfected adults on personality questionnaires or on a panel of behavioral tests, several differences were found. Other studies have demonstrated reduced psychomotor performance in affected individuals. Possible mechanisms by which T. gondii may affect human behavior include its effect on dopamine and on testosterone.
Flegr
Jaroslav
J
Departmeent of Parasitology, Faculty of Science, Charles University, Vinicná 7, CZ-128 44 Praha 2, Czech Republic. flegr@cesnet.cz
D000328:Adult; D000367:Age Factors; D000818:Animals; D000913:Antibodies, Protozoan / Q000097:blood; D002416:Cattell Personality Factor Questionnaire; D002908:Chronic Disease; D018153:Czech Republic; D005260:Female; D006801:Humans; D008297:Male; D011247:Pregnancy; D011597:Psychomotor Performance / Q000502:physiology; D011930:Reaction Time; D012559:Schizophrenia / Q000175:diagnosis / Q000276:immunology / Q000469:parasitology*; D012565:Schizophrenic Psychology; D014122:Toxoplasma / Q000276:immunology; D016781:Toxoplasmosis, Cerebral / Q000175:diagnosis / Q000276:immunology / Q000469:parasitology* / Q000523:psychology
D000913:Antibodies, Protozoan