title: Growth inhibition of Trichophyton species by Pseudomonas aeruginosa.
abstract: OBJECTIVE
  To assess the ability of Pseudomonas aeruginosa to inhibit the growth of Trichophyton mentagrophytes (TM) and Trichophyton rubrum (TR).
  
  
  METHODS
  Pseudomonas aeruginosa, Escherichia coli, or Staphylococcus epidermidis were grown in co-culture with either TM or TR.
  
  
  METHODS
  An academic medical center.
  
  
  METHODS
  The total fungal units and hyphal-spore ratio were measured at days 1, 5, 10, and 15.
  
  
  RESULTS
  There was a 73% and 46% reduction of total fungal units and a final hyphal-spore ratio of 0.16 and 0.04, respectively, when TM and TR were co-cultured with P aeruginosa. The number of fungal units increased when TM and TR were cultured with E coli (28% and 42%, respectively), S epidermidis (13% and 18%, respectively), and control media (44% and 62%, respectively), and the hyphal-spore ratio increased to above 30 in the presence of S epidermidis, E coli, and control media.
  
  
  CONCLUSIONS
  Pseudomonas aeruginosa exhibits growth inhibitory properties against TM and TR.
authors.affiliation: Department of Dermatology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.
authors.forename: James
authors.initials: J
authors.lastname: Treat
authors.forename: William D
authors.initials: WD
authors.lastname: James
authors.forename: Irving
authors.initials: I
authors.lastname: Nachamkin
authors.forename: John T
authors.initials: JT
authors.lastname: Seykora
mesh_terms: D018920:Coculture Techniques; D003196:Computer Graphics; D004926:Escherichia coli / Q000378:metabolism; D006090:Gram-Negative Bacteria / Q000378:metabolism*; D006131:Growth Inhibitors; D006801:Humans; D011550:Pseudomonas aeruginosa / Q000378:metabolism*; D013212:Staphylococcus epidermidis / Q000378:metabolism; D013997:Time Factors; D014249:Trichophyton / Q000145:classification / Q000254:growth & development* / Q000378:metabolism
chemical_list: D006131:Growth Inhibitors