[Anticoagulant activity of sulfated polysaccharides].
The paper reviews published data on the chemical structure of sulfated polysaccharides of animal, plant, and microbial origin as well as synthetic or semi-synthetic derivatives, and on the anticoagulant activity of these compounds in vitro and in vivo. The influence of sulfated polysaccharides on the plasma and cell hemostasis links is considered. Relationships between the structure and activity and the mechanisms of action are discussed.
Drozd
N N
NN
Bannikova
G E
GE
Makarov
V A
VA
Varlamov
V P
VP
D000818:Animals; D000925:Anticoagulants / Q000737:chemistry* / Q000494:pharmacology*; D006487:Hemostasis / Q000187:drug effects; D006801:Humans; D011134:Polysaccharides / Q000737:chemistry / Q000494:pharmacology*; D013431:Sulfates / Q000737:chemistry / Q000494:pharmacology*
D000925:Anticoagulants; D011134:Polysaccharides; D013431:Sulfates