title: Base-assisted regio- and diastereoselective conversion of functionalized furans to butenolides using singlet oxygen.
abstract: A facile synthesis of beta-functionalized gamma-hydroxybutenolides was achieved using a Baylis-Hillman reaction followed by singlet oxygen oxidation. The conversion from 3-furfural was regio- and diastereoselective. [reaction: see text].
authors.affiliation: Department of Chemistry & Biomolecular Sciences, Macquarie University, Sydney, NSW 2109, Australia.
authors.forename: Santoshkumar N
authors.initials: SN
authors.lastname: Patil
authors.forename: Fei
authors.initials: F
authors.lastname: Liu
mesh_terms: D015107:4-Butyrolactone / Q000031:analogs & derivatives / Q000138:chemical synthesis* / Q000737:chemistry; D005663:Furans / Q000737:chemistry*; D015394:Molecular Structure; D010100:Oxygen / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D005663:Furans; D015107:4-Butyrolactone; D010100:Oxygen