title: Recurrent acute pancreatitis probably secondary to lisinopril.
abstract: OBJECTIVE
  Few data exist about the incidence of drug-induced acute pancreatitis in the general population. Although angiotensin-converting enzymes are generally well tolerated, acute pancreatitis has been reported in a few subjects treated with captopril, enalapril, and lisinopril. However, to our knowledge, there is no published data regarding recurrent pancreatitis secondary to lisinopril. Herein, we report the case of a 54-year-old man who developed recurrent acute pancreatitis after starting lisinopril.
  
  
  METHODS
  A 54-year-old man with a longstanding history of hypertension, treated with lisinopril 10 mg once daily, presented with acute pancreatitis. Other causes of the disease were ruled out. After cessation of lisinopril, his condition improved and his amylase level decreased. This was his third episode of acute pancreatitis since lisinopril had been started in 2002. After discontinuing lisinopril and beginning treatment with amlodipine 10 mg/d, the patient was well at follow-up examination and has not had another episode of pancreatitis during the subsequent 7 months.
  
  
  CONCLUSIONS
  This case report demonstrates additional evidence of acute pancreatitis associated with an ACE inhibitor.
authors.affiliation: Department of Internal Medicine, Baskent University Faculty of Medicine, Ankara, Turkey. drkanbay@yahoo.com
authors.forename: Mehmet
authors.initials: M
authors.lastname: Kanbay
authors.forename: Haldun
authors.initials: H
authors.lastname: Selcuk
authors.forename: Ugur
authors.initials: U
authors.lastname: Yilmaz
authors.forename: Sedat
authors.initials: S
authors.lastname: Boyacioglu
mesh_terms: D000208:Acute Disease; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000009:adverse effects*; D006801:Humans; D017706:Lisinopril / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D010195:Pancreatitis / Q000139:chemically induced*; D012008:Recurrence
chemical_list: D000806:Angiotensin-Converting Enzyme Inhibitors; D017706:Lisinopril