[Polycystic ovary syndrome. Prototype of a cardio-metabolic syndrome].
Polycystic ovary syndrome (PCOS) is a common endocrine disorder affecting women in the reproductive age and is a major cause of anovulation, hyperandrogenism and infertility. Since obesity and insulin resistance are predominant features of women with PCOS, a variety of metabolic disturbances are associated. There is a marked increase in the risk of developing type-2 diabetes in these patients and a majority of women with PCOS will subsequently harbour an enhanced cardiovascular risk.
Heutling
D
D
1. Medizinische Klinik, Universitätsklinikum Schleswig-Holstein, Campus Lübeck, Lübeck, Deutschland.
Schulz
H
H
Randeva
H
H
Dodt
C
C
Lehnert
H
H
D002318:Cardiovascular Diseases / Q000401:mortality* / Q000503:physiopathology*; D015897:Comorbidity; D003924:Diabetes Mellitus, Type 2 / Q000401:mortality* / Q000503:physiopathology*; D005260:Female; D006801:Humans; D024821:Metabolic Syndrome / Q000401:mortality* / Q000503:physiopathology*; D008954:Models, Biological; D015995:Prevalence; D018570:Risk Assessment / Q000379:methods*; D012307:Risk Factors; D015996:Survival Rate