title: Cationic comb-type copolymers for boosting DNA-fueled nanomachines.
abstract: For the better applications and developments of DNA nanomachines, their responding kinetics, output, and sequence-selectivity need to be improved. Furthermore, the DNA nanomachines currently have several limitations in operating conditions. Here we show that a simple addition of a cationic comb-type copolymer, poly(l-lysine)-graft-dextran, produces the robust and quick responses of DNA nanomachines under moderate conditions including physiologically relevant conditions even at very low strand concentrations (nanomoles per liter range) through hybrid stabilization and DNA strand exchange acceleration.
authors.affiliation: Institute for Materials Chemistry and Engineering, Kyushu University, 6-10-1 Hakozaki, Higashi, Fukuoka 812-8581, Japan.
authors.forename: Sung Won
authors.initials: SW
authors.lastname: Choi
authors.forename: Naoki
authors.initials: N
authors.lastname: Makita
authors.forename: Satoru
authors.initials: S
authors.lastname: Inoue
authors.forename: Charles
authors.initials: C
authors.lastname: Lesoil
authors.forename: Asako
authors.initials: A
authors.lastname: Yamayoshi
authors.forename: Arihiro
authors.initials: A
authors.lastname: Kano
authors.forename: Toshihiro
authors.initials: T
authors.lastname: Akaike
authors.forename: Atsushi
authors.initials: A
authors.lastname: Maruyama
mesh_terms: D001483:Base Sequence; D002412:Cations; D004247:DNA / Q000737:chemistry*; D003911:Dextrans / Q000737:chemistry*; D007700:Kinetics; D049329:Nanostructures; D011107:Polylysine / Q000737:chemistry*; D012965:Sodium Chloride / Q000737:chemistry
chemical_list: D002412:Cations; D003911:Dextrans; D011107:Polylysine; D012965:Sodium Chloride; D004247:DNA