Understanding ion channel selectivity and gating and their role in cellular signalling.
Ion channels play an essential role in the communication between and within cells. Here some of the different ion channel proteins and the roles they perform are introduced, before a discussion of the mechanisms by which they discriminate between different ion types and open and close to allow the passage of ions at the appropriate times.
Corry
Ben
B
School of Biomedical, Biomolecular and Chemical Sciences, The University of Western Australia, Crawley, WA 6009, Australia. ben@theochem.uwa.edu.au
D000818:Animals; D006096:Gramicidin / Q000737:chemistry; D006801:Humans; D015640:Ion Channel Gating; D007473:Ion Channels / Q000502:physiology*; D008024:Ligands; D008954:Models, Biological; D017434:Protein Structure, Tertiary; D015398:Signal Transduction; D013329:Structure-Activity Relationship
D007473:Ion Channels; D008024:Ligands; D006096:Gramicidin