Future of toxicology--lipid peroxidation in the future: from biomarker to etiology.
On the basis of a large number of reports concerning the detection of lipid peroxidation products as biomarkers in human diseases, there is no doubt that their steady-state levels increase under pathophysiological states associated with oxidative stress. The key question is whether they play any causative roles. This may be a matter of primary concern, which represents an important direction to pursue in the future of toxicology. My latest approach from autoimmune response induced by lipid peroxidation products will be illustrated.
Uchida
Koji
K
Graduate School of Bioagricultural Sciences, Nagoya University, Nagoya 464-8601, Japan. uchidak@agr.nagoya-u.ac.jp
D015415:Biomarkers; D000939:Epitopes; D006801:Humans; D015227:Lipid Peroxidation; D014116:Toxicology / Q000639:trends*
D015415:Biomarkers; D000939:Epitopes