title: Supernumerary minute ring chromosome 14 in a man with primary infertility and left varicocele.
abstract: OBJECTIVE
  To describe a case of supernumerary minute ring chromosome (SMRC) in an infertile man, with the concurrent finding of a left varicocele.
  
  
  METHODS
  Case report.
  
  
  METHODS
  Urologic infertility clinic in a university hospital.
  
  
  METHODS
  Male patient presenting with primary infertility.
  
  
  METHODS
  Karyotyping, genetic counseling, and microsurgical left varicocelectomy.
  
  
  METHODS
  Sperm concentration and motility, chromosomal number and structure.
  
  
  RESULTS
  Fluorescence in situ hybridization revealing SMRC 14. Sperm concentration and motility improved after left varicocele repair.
  
  
  CONCLUSIONS
  A karyotype should be included in the evaluation of severe oligospermia. Although SMRC 14 may be associated with fertility problems, repair of a coexisting varicocele should be considered in these patients.
authors.affiliation: Department of Urology, University of Iowa, Iowa City, Iowa 52242-1089, USA.
authors.forename: Brandon C
authors.initials: BC
authors.lastname: Stahl
authors.forename: Shivanand R
authors.initials: SR
authors.lastname: Patil
authors.forename: Craig H
authors.initials: CH
authors.lastname: Syrop
authors.forename: Amy E T
authors.initials: AE
authors.lastname: Sparks
authors.forename: Moshe
authors.initials: M
authors.lastname: Wald
mesh_terms: D000328:Adult; D002883:Chromosomes, Human, Pair 14; D006801:Humans; D007248:Infertility, Male / Q000175:diagnosis* / Q000235:genetics* / Q000601:surgery; D008297:Male; D012303:Ring Chromosomes; D014646:Varicocele / Q000175:diagnosis* / Q000235:genetics* / Q000601:surgery