[Neurotoxicity of cyclosporine].
Using cyclosporine as an immunosuppressive drug allowed increasing survival of grafts as well as patients. Despite this drug is being safely used for many years, it can cause complications. The most often complications are nefrotoxicity, hepatotoxicity, diabetes mellitus, arterial hypertension and neurotoxicity. The most often manifestation of neurotoxicity are tremor, leucoencephalopathia, headache and even seizures. Among risk factors we can enumerate arterial hypertetension, low cholesterol level, hypomagnesemia and previous cerebrovascular insufficiency.
Kozłowska
Iwona
I
Z Kliniki Nefrologii, Transplantologii i Chorób Wewnetrznych Pomorskiej Akademii Medycznej, Szczecinie.
Rózańiski
Jacek
J
Ciechanowski
Kazimierz
K
D016572:Cyclosporine / Q000009:adverse effects* / Q000627:therapeutic use; D005260:Female; D006084:Graft Rejection / Q000188:drug therapy*; D016027:Heart Transplantation / Q000009:adverse effects; D006801:Humans; D006973:Hypertension / Q000139:chemically induced; D007166:Immunosuppressive Agents / Q000009:adverse effects*; D016030:Kidney Transplantation / Q000009:adverse effects; D008297:Male; D009404:Nephrotic Syndrome / Q000139:chemically induced; D020258:Neurotoxicity Syndromes / Q000209:etiology*
D007166:Immunosuppressive Agents; D016572:Cyclosporine