title: Laser-fiber system for ablation of intraocular tissue using the fourth harmonic of a pulsed Nd:YAG laser.
abstract: We report on a method for delivering high fluence pulsed 266 nm laser radiation to the target tissue via an optical fiber. The fourth harmonic of a Nd:YAG laser was concentrated using a hollow glass taper and launched into an optical fiber. Fluences of up to 2 J/cm(2) were routinely output at the tapered optical fiber tip. The maximum fluence generated before failure of the optical fiber was between 3.5 and 8 J/cm(2). Ablation of ocular tissue was demonstrated using fluences of 1.0 and 0.4 J/cm(2). The delivery system has the potential for use in intraocular surgical procedures.
authors.affiliation: The University of Western Australia, Nedlands, Perth, Australia.
authors.forename: Joseph
authors.initials: J
authors.lastname: Miller
authors.forename: Paula K
authors.initials: PK
authors.lastname: Yu
authors.forename: Stephen J
authors.initials: SJ
authors.lastname: Cringle
authors.forename: Dao-Yi
authors.initials: DY
authors.lastname: Yu
mesh_terms: D000818:Animals; D004867:Equipment Design; D005898:Glass; D006801:Humans; D053685:Laser Therapy / Q000295:instrumentation* / Q000379:methods*; D007834:Lasers; D009354:Neodymium / Q000737:chemistry; D055095:Optics and Photonics; D012160:Retina / Q000601:surgery*; D012984:Software; D013552:Swine
chemical_list: D009354:Neodymium