title: Design and evaluation of the tandem target for a simultaneous production of [11C]CH4 and [18F]-fluoride.
abstract: The tandem target for a simultaneous production of [11C]CH4 and [(18)F]-fluoride has been designed and evaluated. A separate recovery system has been applied for a simultaneous collection of [11C]CH4 and [(18)F]-fluoride after a bombardment. The [11C]CH4 target was placed in front, and the [18F]-fluoride target was posted successively. An aluminum grid was employed between the two target cavities to improve the burst pressure of the titanium foil during an irradiation. It was demonstrated that a useful amount of [11C]CH4 and [18F]-fluoride can be produced simultaneously by this newly designed system.
authors.affiliation: Radiation Application Division, Korea Atomic Energy Research Institute, Jeongup-si, Jeollabuk-do 580-185, South Korea. sdyang@kaeri.re.kr
authors.forename: Seung Dae
authors.initials: SD
authors.lastname: Yang
authors.forename: Sang Wook
authors.initials: SW
authors.lastname: Kim
authors.forename: Min Goo
authors.initials: MG
authors.lastname: Hur
authors.forename: Jeong Hoon
authors.initials: JH
authors.lastname: Park
authors.forename: Jong-Seo
authors.initials: JS
authors.lastname: Chai
authors.forename: Kook Hyun
authors.initials: KH
authors.lastname: Yu
mesh_terms: D002250:Carbon Radioisotopes / Q000737:chemistry*; D004339:Drug Compounding / Q000379:methods; D004353:Drug Evaluation, Preclinical; D005461:Fluorine / Q000737:chemistry*; D005462:Fluorine Radioisotopes / Q000737:chemistry*; D007553:Isotope Labeling / Q000379:methods*; D008697:Methane / Q000737:chemistry*; D019275:Radiopharmaceuticals / Q000138:chemical synthesis*
chemical_list: D002250:Carbon Radioisotopes; D005462:Fluorine Radioisotopes; D019275:Radiopharmaceuticals; D005461:Fluorine; D008697:Methane