[Simultaneous defect of visual fields and loss of libido--a coincidence?].
We present the case of a 60 year old male patient with incidentally detected visual abnormalities. Detailed personal history revealed a hypogonadism that had been present for several years. Further investigations established the diagnosis of an infiltrative macroadenoma. Medical treatment with cabergoline led to a rapid regression of ophthalmologic symptoms and, subsequently, of tumor size. In male subjects symptoms of hypogonadism are often reported only late in the course of the disease, thereby leading to a generally larger tumor size at the point of diagnosis. In contrast to other pituitary tumors that are mainly treated by surgery, medical treatment with dopamine agonists is the principal therapeutic option in prolactinomas.
Jenni
S
S
Poliklinik für Endokrinologie, Diabetologie und Klinische Ernährung, Inselspital, Universitätsspital Bern. stefan.jenni@insel.ch
Seiler
R
R
Christ
E R
ER
Stettler
C
C
D000077465:Cabergoline; D003937:Diagnosis, Differential; D018491:Dopamine Agonists / Q000627:therapeutic use; D007172:Erectile Dysfunction / Q000188:drug therapy / Q000209:etiology*; D004873:Ergolines / Q000627:therapeutic use; D006801:Humans; D006966:Hyperprolactinemia / Q000188:drug therapy / Q000209:etiology; D007006:Hypogonadism / Q000188:drug therapy / Q000209:etiology*; D007989:Libido / Q000187:drug effects; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009408:Nerve Compression Syndromes / Q000175:diagnosis / Q000188:drug therapy; D009901:Optic Nerve Diseases / Q000175:diagnosis / Q000188:drug therapy; D010911:Pituitary Neoplasms / Q000175:diagnosis* / Q000188:drug therapy; D015175:Prolactinoma / Q000175:diagnosis* / Q000188:drug therapy; D014794:Visual Fields / Q000187:drug effects
D018491:Dopamine Agonists; D004873:Ergolines; D000077465:Cabergoline