title: Screening for acute HIV infection: lessons learned.
abstract: Human immunodeficiency virus (HIV) nucleic acid testing is increasingly being used by researchers and public health screening programs to identify highly infectious, HIV antibody-negative individuals with acute HIV infection. We present cases to illustrate unusual instances of acute HIV screening, which include "window period" testing and the discovery of low-level HIV RNA.
authors.affiliation: Department of Medicine, University of Washington, Seattle, WA, USA. jstekler@u.washington.edu
authors.forename: Joanne
authors.initials: J
authors.lastname: Stekler
authors.forename: Janine
authors.initials: J
authors.lastname: Maenza
authors.forename: Claire E
authors.initials: CE
authors.lastname: Stevens
authors.forename: Paul D
authors.initials: PD
authors.lastname: Swenson
authors.forename: Robert W
authors.initials: RW
authors.lastname: Coombs
authors.forename: Robert W
authors.initials: RW
authors.lastname: Wood
authors.forename: Mary S
authors.initials: MS
authors.lastname: Campbell
authors.forename: David C
authors.initials: DC
authors.lastname: Nickle
authors.forename: Ann C
authors.initials: AC
authors.lastname: Collier
authors.forename: Matthew R
authors.initials: MR
authors.lastname: Golden
mesh_terms: D000208:Acute Disease; D005188:False Negative Reactions; D006678:HIV / Q000302:isolation & purification; D015483:HIV Antibodies / Q000097:blood*; D015658:HIV Infections / Q000175:diagnosis* / Q000235:genetics; D018023:HIV Seronegativity; D006679:HIV Seropositivity; D006801:Humans; D008403:Mass Screening; D021141:Nucleic Acid Amplification Techniques / Q000379:methods; D012367:RNA, Viral / Q000097:blood*; D012680:Sensitivity and Specificity; D014766:Viremia / Q000175:diagnosis
chemical_list: D015483:HIV Antibodies; D012367:RNA, Viral