[Effects of remifentanil in children undergoing endoscopic-assisted adenoidectomy].
OBJECTIVE
To observe the effect of remifentanil on hemodynamic and angiotentratin- II in children undergoing endoscopic-assisted adenoidectomy.


METHODS
Thirty patients, ASA I -II , were randomly divided into two groups , remifentanil group and fentanyl group. Remifentanil group received remifentanil combined with propofol anesthesia, fentanyl group received fentanyl combined with propofol anesthesia . Vecuronium was given as muscle relaxant in both groups. ECG, HR, BP, Sa02 were monitored in both groups during operation,and peripheral venous blood samples were taken on 1d before operation(T1),at the time of endotracheal intubation (T2 ), 10 minutes after operation beginning (T3 ),5 minutes after extubation (T4 ) for check angiotentratin- II , then recorded the time of anesthesia, the time of recovery from anesthesia and the time of extubation.


RESULTS
Comparing with T1, T2, and T3 were significant lower in both group about the HR, BP and angiotentratin-II. There was no significant difference in two groups about SaO2. HR and BP is little lower in remifentanil group than in fentanyl group . The anesthesia time was significantly longer in Remifentanil group than that in fentanyl group. The recovery time was significantly shorter in Remifentanil group than that in fentanyl group. The extubation time was significantly shorter in remifentanil group than that in fentanyl group.


CONCLUSIONS
Remifentanil is better than fentanyl for stabilizing hemodynamic,decreasing the stress responses,reducing the time of recovery and extubation in children undergoing endoscopic-assisted adenoidectomy.
Li
Songmei
S
Department of Anesthesia, Huaihe Hospital of Henan University, Kaifeng, 475000, China. leesm326@yahoo.com.cn
Xu
Haixia
H
Guo
Sulian
S
D000233:Adenoidectomy / Q000379:methods*; D000293:Adolescent; D018686:Anesthetics, Intravenous / Q000494:pharmacology*; D002648:Child; D002675:Child, Preschool; D004724:Endoscopy; D005283:Fentanyl / Q000494:pharmacology; D006801:Humans; D010880:Piperidines / Q000494:pharmacology*; D015742:Propofol / Q000494:pharmacology; D000077208:Remifentanil
D018686:Anesthetics, Intravenous; D010880:Piperidines; D000077208:Remifentanil; D005283:Fentanyl; D015742:Propofol