Selective toxic effects of polyunsaturated fatty acids derived from Ulva fasciata on red tide phyotoplankter species.
Alpha-linolenic acid and linoleic acid isolated from Ulva fasciata showed toxic effects on red tide phytoplankters in a concentration-dependent manner. Among six species tested, raphidophycean flagellate Heterosigma akashiwo was the most susceptible to these fatty acids, and 50% lethal concentrations (LC50) of alpha-linolenic acid and linoleic acid were estimated to be 0.58 and 1.91 microg/ml respectively, whereas dinoflagellate Gymnodinium impudicum and Heterocapsa circularisquama were highly resistant and no significant toxic effects were observed up to 1,000 microg/ml. Both fatty acids were less toxic to fish (devil stinger), zooplankters (brine shrimp and rotifer), and mammalian cell lines (U937, HeLa, Vero, and CHO cells) than H. akashiwo.
Alamsjah
Mochammad Amin
MA
Graduate School of Science and Technology, Nagasaki University, Japan.
Ishibe
Keiko
K
Kim
Daekyung
D
Yamaguchi
Kenichi
K
Ishibashi
Fumito
F
Fujita
Yuji
Y
Oda
Tatsuya
T
D000818:Animals; D002460:Cell Line; D002470:Cell Survival / Q000187:drug effects; D002522:Chlorocebus aethiops; D006224:Cricetinae; D004141:Dinoflagellida; D005231:Fatty Acids, Unsaturated / Q000737:chemistry* / Q000633:toxicity*; D006801:Humans; D010839:Phytoplankton / Q000737:chemistry*; D044445:Ulva / Q000737:chemistry*
D005231:Fatty Acids, Unsaturated