title: Sequencing of a novel HLA-A allele, A*6836, showing a Bw4 epitope.
abstract: A novel A*6836 allele was completely characterized by sequence-based typing (SBT) in a cord blood sample from an Ecuadorian donor. A*6836 discloses six clustered amino acid residue changes at the alpha-1 domain, codons 76-83, regarding its closer A*680102 allele. Therefore, A*6836 would be a new human leukocyte antigen (HLA)-A molecule showing a Bw4-epitope.
authors.affiliation: Departamento de Histocompatibilidad, Centro de Transfusión de la Comunidad de Madrid, Madrid, Spain. abalas.trans@salud.madrid.org
authors.forename: A
authors.initials: A
authors.lastname: Balas
authors.forename: F
authors.initials: F
authors.lastname: García-Sánchez
authors.forename: J L
authors.initials: JL
authors.lastname: Vicario
mesh_terms: D000483:Alleles; D000939:Epitopes / Q000276:immunology / Q000302:isolation & purification*; D005312:Fetal Blood; D015234:HLA-A Antigens / Q000737:chemistry / Q000235:genetics* / Q000276:immunology*; D015235:HLA-B Antigens / Q000276:immunology / Q000302:isolation & purification*; D006801:Humans; D007231:Infant, Newborn; D017422:Sequence Analysis, DNA; D020539:Sequence Analysis, Protein
chemical_list: D000939:Epitopes; D015234:HLA-A Antigens; D015235:HLA-B Antigens; C042388:HLA-Bw4 antigen