title: Changes of heavy metal concentrations in cross-sections of human femur head.
abstract: The concentrations of 12 elements (Ni, Ma, Cr, Cd, Pb, Cu, Fe, Zn, Mg, K, Na, Ca) were determined in cross-sections of human femur heads. The highest concentrations of these elements was found in the cortical bone, and the lowest concentrations occurred in the trabecular bone, with exception of the E cross-section, in which the lowest values were found in articular cartilage. The average concentrations of Na, Ca, K, and Mg were highest in cortical bone and lowest in articular cartilage. Pb was found in higher concentrations in articular cartilage and lowest in trabecular bone, with exception of cross-sections A and E. The Fe contents in the cortical parts were highest in cross-sections A, B, and D. Cu was highest in cross-sections B, C, and D of articular cartilage. These results show that the contents of the selected metals in the femur head varied considerably. As expected, the largest concentrations were found in the outmost part of cross-section E and the lowest in its innermost one, possibly related to mechanical stress.
authors.affiliation: Department of Toxicology, Faculty of Pharmacy, Silesian University of Medicine, 41-200 Sosnowiec, Poland. bbrodziak@slam.katowice.pl
authors.forename: Barbara
authors.initials: B
authors.lastname: Brodziak-Dopierala
authors.forename: Jerzy
authors.initials: J
authors.lastname: Kwapulinski
authors.forename: Zbigniew
authors.initials: Z
authors.lastname: Gajda
authors.forename: Jerzy
authors.initials: J
authors.lastname: Toborek
authors.forename: Mariusz
authors.initials: M
authors.lastname: Bogunia
mesh_terms: D005269:Femur / Q000737:chemistry*; D006801:Humans; D019216:Metals, Heavy / Q000032:analysis*; D013054:Spectrophotometry, Atomic
chemical_list: D019216:Metals, Heavy