title: A case of equine motor neuron disease (EMND).
abstract: We report a case of EMND in a heavy horse that was bred and trained in Hokkaido, Japan. Clinical symptoms included severe ataxia of all four limbs, tilted head, lethargy, and flaccid lips. Numerous axonal degenerations and swellings were observed in nuclei, mostly in the cerebellar dentate nucleus and the nucleus of the hypoglossal nerve, and in the ventral horn of the spinal cord. In the ventral horn of the spinal cord, neuronal degeneration, swelling, and/or necrosis were observed sporadically. The case was diagnosed as EMND from the clinical symptoms and pathological findings.
authors.affiliation: Department of Clinical Veterinary Science, Obihiro University of Agriculture and Veterinary Medicine, Inada, Obihiro, Hokkaido, Japan.
authors.forename: Naoki
authors.initials: N
authors.lastname: Sasaki
authors.forename: Michiaki
authors.initials: M
authors.lastname: Yamada
authors.forename: Yoshinori
authors.initials: Y
authors.lastname: Morita
authors.forename: Hidefumi
authors.initials: H
authors.lastname: Furuoka
authors.forename: Miyuki
authors.initials: M
authors.lastname: Itoh
authors.forename: Motoyoshi
authors.initials: M
authors.lastname: Satoh
authors.forename: Haruo
authors.initials: H
authors.lastname: Yamada
mesh_terms: D000818:Animals; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D001921:Brain / Q000473:pathology; D003907:Dexamethasone / Q000627:therapeutic use; D006734:Horse Diseases / Q000175:diagnosis* / Q000188:drug therapy; D006736:Horses; D008297:Male; D016472:Motor Neuron Disease / Q000175:diagnosis / Q000188:drug therapy / Q000662:veterinary*; D013116:Spinal Cord / Q000473:pathology
chemical_list: D000893:Anti-Inflammatory Agents; D003907:Dexamethasone