title: Ability of monocyte-derived dendritic cells to secrete oxygen radicals in response to formyl peptide receptor family agonists compared to that of myeloid and plasmacytoid dendritic cells.
abstract: We show that human monocyte-derived dendritic cells (DC) differ considerably from freshly isolated blood-derived myeloid and plasmacytoid DC in their abilities to produce reactive oxygen species in response to different agonists to the formyl peptide receptor family and are thus poor representatives of blood DC in this field of research.
authors.affiliation: Department of Rheumatology and Inflammation Research, Guldhedsgatan 10A, 413 46 Göteborg, Sweden. Kristina.Eriksson@microbio.gu.se
authors.forename: Anna
authors.initials: A
authors.lastname: Karlsson
authors.forename: Erik
authors.initials: E
authors.lastname: Nygren
authors.forename: Jennie
authors.initials: J
authors.lastname: Karlsson
authors.forename: Inger
authors.initials: I
authors.lastname: Nordström
authors.forename: Claes
authors.initials: C
authors.lastname: Dahlgren
authors.forename: Kristina
authors.initials: K
authors.lastname: Eriksson
mesh_terms: D003713:Dendritic Cells / Q000187:drug effects / Q000378:metabolism*; D005609:Free Radicals; D006801:Humans; D009000:Monocytes / Q000166:cytology / Q000187:drug effects / Q000378:metabolism*; D022423:Myeloid Cells / Q000187:drug effects / Q000378:metabolism*; D009842:Oligopeptides / Q000494:pharmacology; D017382:Reactive Oxygen Species / Q000378:metabolism*; D044042:Receptors, Formyl Peptide / Q000819:agonists*
chemical_list: D005609:Free Radicals; D009842:Oligopeptides; D017382:Reactive Oxygen Species; D044042:Receptors, Formyl Peptide; C113617:Trp-Lys-Tyr-Met-Val-Met