title: Scintigraphic evaluation of the proximal metacarpal and metatarsal regions of horses with proximal suspensory desmitis.
abstract: The aim of the study was to characterize radiopharmaceutical uptake patterns in horses with clinical and ultrasonographic evidence of proximal suspensory desmitis. It was hypothesized that radiopharmaceutical uptake in the proximal palmar (plantar) aspect of the third metacarpal (metatarsal) bone would be greater in lame limbs of horses with proximal suspensory desmitis than in sound limbs and that there would be a positive correlation between the severity of ultrasonographic abnormalities and the degree of radiopharmaceutical uptake. Nuclear scintigraphic evaluation of the proximal metacarpal or metatarsal regions of 126 horses with ultrasonographic evidence of proximal suspensory desmitis was performed. In all horses lameness was substantially improved by perineural analgesia of the palmar metacarpal (subcarpal) or plantar metatarsal (subtarsal) nerves. Scintigraphic images were assessed subjectively, by profile analysis and using region of interest analysis. Associations between the degree of ultrasonographic abnormality and radiopharmaceutical uptake ratios and the presence of radiographic abnormalities and radiopharmaceutical uptake ratios were analyzed. Subjectively, the majority of horses had normal radiopharmaceutical uptake. Profile analysis provided little additional information. However with region of interest analysis there was greater radiopharmaceutical uptake ratios in plantar images in the proximal metatarsal regions of lame limbs compared with nonlame limbs. There was no association between radiological abnormalities and radiopharmaceutical uptake ratios. In forelimbs there was no association between ultrasonographic lesion grade and radiopharmaceutical uptake ratios, however in hindlimbs there was a significant relationship between ultrasonographic grade and radiopharmaceutical uptake ratios.
authors.affiliation: Centre for Equine Studies, Animal Health Trust, Lanwades Park, Kentford, Newmarket, Suffolk CB8 7UU, UK. sue.dyson@aht.org.uk
authors.forename: Sue J
authors.initials: SJ
authors.lastname: Dyson
authors.forename: Jo S
authors.initials: JS
authors.lastname: Weekes
authors.forename: Rachel C
authors.initials: RC
authors.lastname: Murray
mesh_terms: D000818:Animals; D006734:Horse Diseases / Q000000981:diagnostic imaging*; D006736:Horses; D007794:Lameness, Animal / Q000000981:diagnostic imaging; D008023:Ligaments, Articular / Q000000981:diagnostic imaging*; D050279:Metacarpal Bones / Q000000981:diagnostic imaging*; D008682:Metatarsal Bones / Q000000981:diagnostic imaging*; D011877:Radionuclide Imaging / Q000662:veterinary; D011996:Records / Q000662:veterinary; D012189:Retrospective Studies; D013669:Technetium Tc 99m Medronate
chemical_list: D013669:Technetium Tc 99m Medronate