Combined factor VIII and IX inhibitors in a non-haemophilic patient: successful treatment with immunosuppressive drugs.
A rare case of a patient with Sjogren syndrome and spontaneously acquired inhibitors of both factor VIII and factor IX is reported. Complete remission was obtained by means of immunosuppressive drugs.
Carmassi
F
F
Department of Internal Medicine, University of Pisa, Pisa, Italy. f.carmassi@int.med.unipi.it
Giannarelli
C
C
De Giorgi
A
A
De Negri
F
F
D001778:Blood Coagulation Disorders / Q000097:blood / Q000150:complications* / Q000188:drug therapy; D019774:Blood Coagulation Factor Inhibitors / Q000097:blood*; D005164:Factor IX / Q000037:antagonists & inhibitors; D005169:Factor VIII / Q000037:antagonists & inhibitors; D006467:Hemophilia A / Q000097:blood / Q000150:complications / Q000188:drug therapy; D002836:Hemophilia B / Q000097:blood / Q000150:complications / Q000188:drug therapy; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D011241:Prednisone / Q000627:therapeutic use*; D012859:Sjogren's Syndrome / Q000097:blood / Q000150:complications* / Q000188:drug therapy
D019774:Blood Coagulation Factor Inhibitors; D007166:Immunosuppressive Agents; D005169:Factor VIII; D005164:Factor IX; D011241:Prednisone