[Multiple recurrent papillomas of the breast: case report].
We report the case of a patient presenting multiple recurrent papillomas of the breast. This mild mammary pathology, developed at the expense of the galactophoric ducts, recurred four times, in a nodular way, in spite of in sano surgical resection. The retrospective study of the cell proliferation and the DNA quantification of the cells constitutive of the papillomas, on several samples, underlined evolutive lesions, which could be predictive of a malignant degeneration. This observation allows us to discuss the management of this rare mild mammary pathology, which can sometimes lead to invasive breast carcinoma.
Grynberg
M
M
Service de Gynécologie-Obstétrique, Institut Mère-Enfant Alix-de-Champagne, Hôpital Maison-Blanche, CHU de Reims,45, rue Cognacq-Jay, 51092 Reims cedex, France.
Graesslin
O
O
Teyssèdre
J
J
Birembaut
P
P
Quéreux
C
C
D000328:Adult; D001940:Breast / Q000473:pathology* / Q000601:surgery; D001943:Breast Neoplasms / Q000175:diagnosis* / Q000601:surgery; D002455:Cell Division; D004279:DNA, Viral / Q000032:analysis; D005260:Female; D006801:Humans; D009364:Neoplasm Recurrence, Local / Q000601:surgery; D010212:Papilloma / Q000175:diagnosis* / Q000601:surgery; D012189:Retrospective Studies
D004279:DNA, Viral