title: In vitro activity of API-1252, a novel FabI inhibitor, against clinical isolates of Staphylococcus aureus and Staphylococcus epidermidis.
authors.forename: James A
authors.initials: JA
authors.lastname: Karlowsky
authors.forename: Nancy M
authors.initials: NM
authors.lastname: Laing
authors.forename: Trish
authors.initials: T
authors.lastname: Baudry
authors.forename: Nachum
authors.initials: N
authors.lastname: Kaplan
authors.forename: David
authors.initials: D
authors.lastname: Vaughan
authors.forename: Daryl J
authors.initials: DJ
authors.lastname: Hoban
authors.forename: George G
authors.initials: GG
authors.lastname: Zhanel
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000494:pharmacology*; D001572:Benzofurans / Q000494:pharmacology*; D050753:Enoyl-(Acyl-Carrier-Protein) Reductase (NADH) / Q000037:antagonists & inhibitors*; D004791:Enzyme Inhibitors / Q000737:chemistry / Q000494:pharmacology*; D006801:Humans; D011753:Pyrones / Q000494:pharmacology*; D013203:Staphylococcal Infections / Q000188:drug therapy; D013211:Staphylococcus aureus / Q000187:drug effects* / Q000201:enzymology / Q000302:isolation & purification; D013212:Staphylococcus epidermidis / Q000187:drug effects* / Q000201:enzymology / Q000302:isolation & purification
chemical_list: C521531:API 1252; D000900:Anti-Bacterial Agents; D001572:Benzofurans; D004791:Enzyme Inhibitors; D011753:Pyrones; D050753:Enoyl-(Acyl-Carrier-Protein) Reductase (NADH)