title: Application of morphological and physiological parameters representative of a Brazilian population sample in the respiratory tract model.
abstract: The human respiratory tract model (HRTM) adopted by ICRP in its Publication 66 accounts for the morphology and physiology of the respiratory tract. The characteristics of air drawn into the lungs and exhaled are greatly influenced by the morphology of the respiratory tract, which causes numerous changes in pressure, flow rate, direction and humidity as air moves into and out of the lungs. These characteristics are important to determine the fractional deposition. It is known that the morphology and physiology are influenced by environmental, occupational and economic conditions. The ICRP recommends, for a reliable evaluation of the regional deposition, the use of parameters from a local population wherever such information is available. The main purpose of this study is to verify the influence of using the morphology and physiology parameters representative of a sample of the Brazilian population on the deposition model of the ICRP Publication 66 model.
authors.affiliation: Instituto de Radioproteção e Dosimetria (IRD/CNEN). Av. Salvador Allende S/N, Recreio dos Bandeirantes, CEP: 22780-160, Rio de Janeiro, Brazil. arlene@ird.gov.br
authors.forename: A A
authors.initials: AA
authors.lastname: dos Reis
authors.forename: J C S
authors.initials: JC
authors.lastname: Cardoso
authors.forename: M
authors.initials: M
authors.lastname: C Lourenço
mesh_terms: D000465:Algorithms; D001681:Biological Assay / Q000379:methods*; D001938:Brazil; D003198:Computer Simulation; D004781:Environmental Exposure / Q000032:analysis*; D006801:Humans; D038622:Internationality; D008954:Models, Biological; D011829:Radiation Dosage; D011834:Radiation Monitoring / Q000379:methods*; D011835:Radiation Protection / Q000379:methods*; D011868:Radioisotopes / Q000032:analysis / Q000493:pharmacokinetics*; D015203:Reproducibility of Results; D012137:Respiratory System / Q000033:anatomy & histology* / Q000378:metabolism*; D012680:Sensitivity and Specificity
chemical_list: D011868:Radioisotopes