title: Anticipating the 1,000 dollar genome.
abstract: A new generation of DNA-sequencing platforms will become commercially available over the next few years. These instruments will enable re-sequencing of human genomes at a previously unimagined throughput and low cost. Here, I examine why the 1,000 dollar human genome is an important goal for research and clinical diagnostics, and what will be required to achieve it.
authors.affiliation: Genome Sequencing Center, Washington University School of Medicine, 4444 Forest Park Boulevard, St, Louis, MO 63108, USA. emardis@wustl.edu
authors.forename: Elaine R
authors.initials: ER
authors.lastname: Mardis
mesh_terms: D004864:Equipment and Supplies / Q000191:economics; D015894:Genome, Human; D006801:Humans; D017422:Sequence Analysis, DNA / Q000191:economics* / Q000295:instrumentation