title: The antimicrobial effects of root canal irrigation and medication.
abstract: The role of microorganisms in the development and maintenance of pulpal and periapical inflammation have been well documented. The success of root canal treatment largely depends on the elimination of microbial contamination from the root canal system. Although mechanical instrumentation of root canals can reduce bacterial population, effective elimination of bacteria cannot be achieved without the use of antimicrobial root canal irrigation and medication. This review will discuss the antimicrobial effects of the known root canal irrigants and medicaments and explore future developments in the field.
authors.affiliation: Department of Restorative Dentistry, School of Clinical Dentistry, Queen's University Belfast, Belfast, Northern Ireland. ielkarim@hotmail.com
authors.forename: Ikhlas
authors.initials: I
authors.lastname: El Karim
authors.forename: John
authors.initials: J
authors.lastname: Kennedy
authors.forename: David
authors.initials: D
authors.lastname: Hussey
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000627:therapeutic use*; D002126:Calcium Hydroxide / Q000737:chemistry / Q000627:therapeutic use*; D003786:Dental Pulp Cavity / Q000382:microbiology*; D006801:Humans; D012388:Root Canal Irrigants / Q000737:chemistry / Q000627:therapeutic use*
chemical_list: D000900:Anti-Bacterial Agents; D012388:Root Canal Irrigants; D002126:Calcium Hydroxide