title: Synthesis and antigenotoxic activity of some naphtho[2,1-b]pyrano[3,2-e][1,2,4]triazolo[1,5-c]pyrimidine derivatives.
abstract: In this study, some pyranotriazolopyrimidine derivatives were synthesised by reacting ethoxymethyleneamino derivatives with hydrazides. Their structures were elucidated by IR, (1)H NMR, and (13)C NMR spectroscopic data and elemental analyses. Antigenotoxic activity of the obtained compounds was tested in Escherichia coli PQ37 by using the SOS chromotest.
authors.affiliation: Laboratoire de Chimie Appliquée: Hétérocycles, Corps Gras et Polymères, Faculté des Sciences de Sfax, Sfax, Tunisia.
authors.forename: Fakher
authors.initials: F
authors.lastname: Chabchoub
authors.forename: Mehdi
authors.initials: M
authors.lastname: Messaâd
authors.forename: Hédi
authors.initials: H
authors.lastname: Ben Mansour
authors.forename: Leila
authors.initials: L
authors.lastname: Chekir-Ghedira
authors.forename: Mansour
authors.initials: M
authors.lastname: Salem
mesh_terms: D016587:Antimutagenic Agents / Q000138:chemical synthesis* / Q000494:pharmacology*; D004926:Escherichia coli / Q000187:drug effects; D009682:Magnetic Resonance Spectroscopy; D011743:Pyrimidines / Q000138:chemical synthesis* / Q000494:pharmacology*; D013055:Spectrophotometry, Infrared
chemical_list: D016587:Antimutagenic Agents; D011743:Pyrimidines