Treatment and prevention of depression after surgery for hip fracture in older people: randomized, controlled trials.
OBJECTIVE
To evaluate the effect of a psychiatric intervention in treating depression (treatment study) and the effect of a psychological treatment in preventing depression (prevention study) after hip fracture in older people.


METHODS
Two linked randomized, controlled trials.


METHODS
Orthopedic units in Manchester, England.


METHODS
Two hundred ninety-three older people who had undergone surgery for a fractured hip: 121 in the treatment study and 172 in the prevention study.


METHODS
The Geriatric Depression Scale and Hospital Anxiety and Depression Scale for mood, functional tests for mobility and pain measures.


RESULTS
There was a slight reduction in depressive symptoms in the active arm of the treatment study. In the prevention study, there was no significant difference in incident depression between the psychological intervention and treatment as usual. There were no differences in the functional and pain outcomes.


CONCLUSIONS
The results from these two randomized, controlled trials show that, after hip fracture surgery, no statistically significant benefits can be achieved from a psychiatric intervention in people who are depressed or a psychological intervention to prevent the onset of depression.
Burns
Alistair
A
Division of Psychiatry, University of Manchester, Manchester, UK. alistair.burns@manchester.ac.uk
Banerjee
Sube
S
Morris
Julie
J
Woodward
Yvonne
Y
Baldwin
Robert
R
Proctor
Rebekah
R
Tarrier
Nicholas
N
Pendleton
Neil
N
Sutherland
Deborah
D
Andrew
Glynne
G
Horan
Mike
M
D000369:Aged, 80 and over; D000928:Antidepressive Agents / Q000627:therapeutic use; D015928:Cognitive Behavioral Therapy; D003863:Depression / Q000175:diagnosis / Q000209:etiology / Q000517:prevention & control* / Q000628:therapy*; D005260:Female; D006620:Hip Fractures / Q000523:psychology* / Q000601:surgery; D006801:Humans; D016015:Logistic Models; D008297:Male; D011183:Postoperative Complications / Q000523:psychology; D016896:Treatment Outcome
D000928:Antidepressive Agents