Combined mass spectrometry and dynamic chemistry approach to identify metalloenzyme inhibitors.
Liénard
Benoît M R
BM
Chemistry Research Laboratory, Mansfield Road, Oxford OX1 3TA, UK.
Selevsek
Nathalie
N
Oldham
Neil J
NJ
Schofield
Christopher J
CJ
D000465:Algorithms; D001665:Binding Sites; D003198:Computer Simulation; D004791:Enzyme Inhibitors / Q000138:chemical synthesis / Q000494:pharmacology*; D013058:Mass Spectrometry / Q000379:methods*; D008667:Metalloproteins / Q000037:antagonists & inhibitors* / Q000737:chemistry; D008956:Models, Chemical; D013329:Structure-Activity Relationship; D013438:Sulfhydryl Compounds / Q000737:chemistry; D065093:beta-Lactamase Inhibitors; D001618:beta-Lactamases / Q000737:chemistry
D004791:Enzyme Inhibitors; D008667:Metalloproteins; D013438:Sulfhydryl Compounds; D065093:beta-Lactamase Inhibitors; D001618:beta-Lactamases