[Drugs affecting thyroid--part II].
The use of several groups of medications may result in thyroid dysfunction. So far the best known medication is amiodarone. The role of other medications and diagnostic agents in causing thyroid dysfunction is quite often forgotten. We presented medications and diagnostic agents commonly used in medical day-to-day practice. We described other than amiodarone iodinated agents and quoted recently published European guidelines in using iodinate contrast agents. We focused on lithium and psychiatric drugs and mechanism of their toxic impact on thyroid gland. These agents are important as they are applied for years (including children). At the end the impact of cytokines on thyroid gland was discussed, medications ever more widely applied in anti-viral and anti-neoplastic therapy.
Kucharczyk
Piotr
P
Wojskowy Instytut Medyczny w Warszawie, Szpitalny Oddzial Ratunkowy CSK MON. pkuch@mediclub.pl
Michałkiewicz
Dariusz
D
Kucharczyk
Aleksandra
A
D000638:Amiodarone / Q000009:adverse effects / Q000494:pharmacology*; D000889:Anti-Arrhythmia Agents / Q000009:adverse effects / Q000494:pharmacology*; D005260:Female; D006801:Humans; D007037:Hypothyroidism / Q000139:chemically induced / Q000188:drug therapy; D007455:Iodine / Q000494:pharmacology*; D008094:Lithium / Q000494:pharmacology*; D008297:Male; D013960:Thyroid Function Tests; D013961:Thyroid Gland / Q000187:drug effects*; D013971:Thyrotoxicosis / Q000139:chemically induced* / Q000188:drug therapy
D000889:Anti-Arrhythmia Agents; D007455:Iodine; D008094:Lithium; D000638:Amiodarone