title: Pertussis in Argentina and France.
abstract: We have studied the epidemiology of pertussis in two countries, Argentina and France, which have similar histories of long-term mass vaccination with a whole-cell vaccine. Both countries display a comparable epidemiology, with an increase of the incidence of the disease in non-vaccinated newborns. We used pulsed-field gel electrophoresis (PFGE) analysis and genotyping to compare Bordetella pertussis clinical isolates recovered in Argentina and France in 2001-2004. The majority of the isolates harbors prn2 allele and belongs to PFGE IVbeta group. Isolates were found to be very similar genetically suggesting a common evolution of the disease in these two countries using the same vaccine.
authors.forename: Valérie
authors.initials: V
authors.lastname: Caro
authors.forename: Valérie
authors.initials: V
authors.lastname: Bouchez
authors.forename: Nicole
authors.initials: N
authors.lastname: Guiso
authors.forename: Blanca
authors.initials: B
authors.lastname: Gatti
authors.forename: Maria Rosa
authors.initials: MR
authors.lastname: Agosti
authors.forename: Silvia E Gonzàlez
authors.initials: SE
authors.lastname: Ayala
mesh_terms: D001118:Argentina / Q000453:epidemiology; D015373:Bacterial Typing Techniques; D001886:Bordetella pertussis / Q000145:classification* / Q000235:genetics* / Q000302:isolation & purification; D016521:Electrophoresis, Gel, Pulsed-Field; D019143:Evolution, Molecular; D005260:Female; D005602:France / Q000453:epidemiology; D005838:Genotype; D006801:Humans; D007115:Immunization Schedule; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D010567:Pertussis Vaccine / Q000008:administration & dosage*; D014611:Vaccination; D014917:Whooping Cough / Q000453:epidemiology* / Q000382:microbiology / Q000517:prevention & control*
chemical_list: D010567:Pertussis Vaccine