title: [Effect of overload environment on IGF-1 expression of osteoblasts].
abstract: In the study of the relationship between cells overloading and the formation, regeneration and growth of bone, the text discussed osteoblasts express IGF-1 variation under overloading environment. The research of overloading on cellular level may elucidate the mechanical effect on the formation, regeneration and growth of bone and the mechanism of cell response in bone.
authors.affiliation: Key Lab. of Biomechanics & Tissue Engineering under the State Ministry of Education, College of Bioengineering, Chongqing University, Chongqing 400044, China.
authors.forename: Juanfang
authors.initials: J
authors.lastname: Shang
authors.forename: Liling
authors.initials: L
authors.lastname: Tang
authors.forename: Xufeng
authors.initials: X
authors.lastname: Niu
authors.forename: Yuanliang
authors.initials: Y
authors.lastname: Wang
mesh_terms: D000818:Animals; D006801:Humans; D007334:Insulin-Like Growth Factor I / Q000096:biosynthesis* / Q000235:genetics; D010006:Osteoblasts / Q000166:cytology / Q000378:metabolism*; D010012:Osteogenesis; D012333:RNA, Messenger / Q000096:biosynthesis / Q000235:genetics; D013314:Stress, Mechanical; D016474:Weight-Bearing / Q000502:physiology*
chemical_list: D012333:RNA, Messenger; D007334:Insulin-Like Growth Factor I