title: [Retrospective study on HIV infection among blood donors in Zhejiang Province over 11-year period (1993 - 2004)].
abstract: To determine HIV prevalence among blood donors in Zhejiang Province from 1993 to 2004 years, almost 6,600, 000 blood donors information were collected and analyzed. Every sample was screened for markers of HIV-1 and HIV-2 by using commercially available ELISA kits twice, and Western blot for confirmation if positive or suspicious result appeared. The results indicated that during the study period, prevalence rate of HIV infection was 0.85/1000 donors (0.085%), with the rising tendency from 1:600000 in 1995 to 1:37500 in 2004. The prevalence of HIV infection in Zhejiang donors was significantly lower than that in donors of other provinces, prevalence of HIV infection in male was higher than that in female. In recent years, the prevalence of HIV in blood donors was obviously increased, but the difference among various populations began to reduce. It is concluded that in a low HIV prevalence area like Zhejiang province where no obvious AIDS occurred, risk for the expansion of the HIV epidemic was on the increase. Screening procedure used in transfusion services nowaday is reliable, but a comprehensive approach is required to make the blood more safe.
authors.affiliation: Blood Center of Zhejiang Province, Hangzhou 310006, China.
authors.forename: Zhong-Hua
authors.initials: ZH
authors.lastname: Meng
authors.forename: Jin
authors.initials: J
authors.lastname: Yang
authors.forename: Hua-Ping
authors.initials: HP
authors.lastname: Zhou
authors.forename: Li-Xing
authors.initials: LX
authors.lastname: Yan
mesh_terms: D001782:Blood Donors; D002681:China / Q000453:epidemiology; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D015658:HIV Infections / Q000517:prevention & control*; D015528:HIV Seroprevalence / Q000639:trends; D015497:HIV-1 / Q000276:immunology; D015498:HIV-2 / Q000276:immunology; D006801:Humans; D008297:Male; D012189:Retrospective Studies; D065227:Transfusion Reaction