Physical activity and dementia: The need for prevention trials.
Dementia is a common and debilitating disease that will increase dramatically for the next 50 years unless a prevention or treatment is identified. This review summarizes the evidence that physical activity is associated with a reduced risk of dementia in older adults and recommends that prevention trials be performed to determine whether this association is causal.
Barnes
Deborah E
DE
Department of Psychiatry, University of California, San Francisco, CA 94121, USA. Deborah.Barnes@ucsf.edu
Whitmer
Rachel A
RA
Yaffe
Kristine
K
D000375:Aging / Q000502:physiology; D002986:Clinical Trials as Topic; D003704:Dementia / Q000503:physiopathology / Q000517:prevention & control*; D006801:Humans; D009043:Motor Activity; D012307:Risk Factors