[Mastocytosis in childhood].
Mastocytosis is a rare multi-symptomatic disorder with overproduction and accumulation of mast cells in different tissues. Mast cells accumulate most often in skin, rarely in bone marrow, lymphnodes, liver and spleen. Symptoms of the disease may be due either to releasing of mediators that are present in mast cells or to affection of organs. Although mastocytosis is regarded as a rare disease in the population, among patients of dermatologists it is much more common. It concerns 5,4 caser per 1000 of cured children. The disease has no original treatment. There is a chance that thanks to to popularisation of knowledge of this disease will be more frequently diagnosed and known better.
Renke
Joanna
J
Klinika Pediatrii, Gastroenterologii i Onkologii, Dzieciecej Akademii Medycznej w Gdańsku. jrenke@amg.gda.pl
Lange
Magdalena
M
D001853:Bone Marrow / Q000473:pathology; D002648:Child; D002675:Child, Preschool; D006801:Humans; D007223:Infant; D018836:Inflammation Mediators / Q000276:immunology; D008407:Mast Cells / Q000378:metabolism / Q000473:pathology; D034721:Mastocytosis, Systemic / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy*; D035583:Rare Diseases; D012867:Skin / Q000473:pathology; D014582:Urticaria Pigmentosa / Q000473:pathology
D018836:Inflammation Mediators