[Advances in molecular oncologic pathology].
Molecular oncologic pathology is a relatively new discipline. It integrates molecular biology with oncologic pathology. Different from the morphology-based traditional diagnostic pathology, molecular oncologic pathology relies on molecular evidences. Complementary to and based on traditional diagnostic pathology, molecular oncologic pathology further predicts the biological behavior of a given tumor and also guides the therapy. This review elaborated the basic concepts and theories of molecular oncologic pathology. It listed several cases to illustrate the clinical applications of molecular oncologic pathology, and to explain how molecular oncologic pathology assists clinicians in cancer diagnosis, treatment, prognostication, and most importantly, cancer prevention.
Chen
Lei
L
State Key Laboratory of Oncology in South China, Guangzhou, Guangdong, 510060, P. R. China. drleichen@gmail.com
D006801:Humans; D008495:Medical Oncology / Q000379:methods*; D025202:Molecular Diagnostic Techniques / Q000379:methods*; D009369:Neoplasms / Q000175:diagnosis / Q000235:genetics / Q000473:pathology* / Q000628:therapy; D010338:Pathology, Clinical / Q000379:methods*; D011786:Quality Control