title: An efficient and chemoselective synthesis of N-substituted 2-aminopyridines via a microwave-assisted multicomponent reaction.
abstract: A facile and selective synthesis of N-substituted 2-aminopyridines is accomplished via microwave-assisted multi-component reactions controlled by the basicity of amine and the nature of solvent. In addition, a possible mechanism accounting for the reaction was proposed.
authors.affiliation: Department of Chemistry, Xuzhou Normal University, Key Laboratory of Biotechnology for Medicinal Plant Xuzhou, Jiangsu, 211116, P R China. laotu@xznu.edu.cn
authors.forename: Shujiang
authors.initials: S
authors.lastname: Tu
authors.forename: Bo
authors.initials: B
authors.lastname: Jiang
authors.forename: Yan
authors.initials: Y
authors.lastname: Zhang
authors.forename: Runhong
authors.initials: R
authors.lastname: Jia
authors.forename: Junyong
authors.initials: J
authors.lastname: Zhang
authors.forename: Changsheng
authors.initials: C
authors.lastname: Yao
authors.forename: Feng
authors.initials: F
authors.lastname: Shi
mesh_terms: D000588:Amines / Q000737:chemistry; D000631:Aminopyridines / Q000138:chemical synthesis* / Q000737:chemistry*; D002625:Chemistry, Organic / Q000379:methods; D020650:Combinatorial Chemistry Techniques; D006361:Heating; D008872:Microwaves; D008956:Models, Chemical; D015394:Molecular Structure; D012997:Solvents / Q000737:chemistry; D013055:Spectrophotometry, Infrared; D017550:Spectroscopy, Fourier Transform Infrared
chemical_list: D000588:Amines; D000631:Aminopyridines; D012997:Solvents