title: Steroidal Sapogenins from Tacca leontopetaloides.
abstract: Diosgenin and its ring-F-hydroxylated derivatives isonarthogenin {spirost-5-ene-3,27-diol {3beta, 22 R, 25 S)} and isonuatigenin {spirost-5-ene-3,25-diol (3beta, 22 R, 25 S)}, together with the 22,25-epoxyfurost-5-ene isomer nuatigenin {furost-5-ene-3,26-diol-22,25-epoxy (3beta, 22 R, 25 S)}, were identified as the major steroidal sapogenins of the acid hydrolysate of an extract of leaves of TACCA LEONTOPETALOIDES by IR, (1)H-NMR, (13)C-NMR, and mass spectroscopy. A diosgenin ester was isolated which apparently arose by ring closure of a glycosylated furostene during hydrolysis.
authors.affiliation: Welsh School of Pharmacy, UWCC, PO Box 13, Cardiff CF1 3XF, U.K.
authors.forename: A M
authors.initials: AM
authors.lastname: Abdel-Aziz
authors.forename: K R
authors.initials: KR
authors.lastname: Brain
authors.forename: G
authors.initials: G
authors.lastname: Blunden
authors.forename: T
authors.initials: T
authors.lastname: Crabb
authors.forename: A K
authors.initials: AK
authors.lastname: Bashir