Pattern of subclinical pulmonary dysfunctions in Parkinson's disease and the effect of levodopa.
We performed a detailed evaluation of pulmonary function in 53 patients with idiopathic Parkinson's disease (PD) who did not have symptoms of pulmonary or cardiac dysfunction. There was a significant pulmonary dysfunction of restrictive type which partially responded to levodopa. Compared to men, women were more severely affected. Pulmonary function assessment is recommended in PD, irrespective of severity of disease.
Pal
Pramod Kumar
PK
Department of Neurology, National Institute of Mental Health and Neurosciences, Bangalore, Karnataka, India. pal.pramod@rediffmail.com
Sathyaprabha
Talakad N
TN
Tuhina
Prasad
P
Thennarasu
Kandavel
K
D000328:Adult; D000978:Antiparkinson Agents / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007980:Levodopa / Q000627:therapeutic use*; D008171:Lung Diseases / Q000188:drug therapy* / Q000209:etiology; D008297:Male; D008875:Middle Aged; D010300:Parkinson Disease / Q000150:complications / Q000188:drug therapy*; D012129:Respiratory Function Tests / Q000379:methods; D012720:Severity of Illness Index
D000978:Antiparkinson Agents; D007980:Levodopa