Tying the knot that binds.
The recent determination of protein structures with knots in their backbone topology has defied previous conventional wisdom. How proteins can fold with a knot is an intriguing question that has been explored for YibK from Haemophilus influenzae in this issue of Structure.
Gloss
Lisa M
LM
School of Molecular Biosciences, Washington State University, Pullman, WA 99164, USA. lmgloss@wsu.edu
D001426:Bacterial Proteins / Q000737:chemistry*; D019281:Dimerization; D006193:Haemophilus influenzae / Q000201:enzymology*; D008780:Methyltransferases / Q000737:chemistry*; D011487:Protein Conformation; D017510:Protein Folding
D001426:Bacterial Proteins; D008780:Methyltransferases