title: Long-term follow-up of high myopic foveoschisis: natural course and surgical outcome.
abstract: OBJECTIVE
  To determine the natural evolution and surgical indications of myopic foveoschisis (MF), which are still poorly documented, and the factors that predict poor prognosis.
  
  
  METHODS
  Retrospective observational case series.
  
  
  METHODS
  Twenty-nine operated and nonoperated cases of MF (29 eyes of 23 patients) were studied. All eyes underwent repeated examinations, including optical coherence tomographic (OCT) recordings, during a mean follow-up of 31.2 months. Special attention was paid to the evolution of visual acuity (VA) and to the thickness of foveoschisis.
  
  
  RESULTS
  Mean refraction was -14.4 diopters, and mean axial length was 29.1 mm. OCT scans revealed that the foveoschisis was associated with macular anomalies: a premacular structure in 13 (44.8%) of 29 eyes, a foveal detachment in 10 (34.5%) of 29 eyes, and a lamellar macular hole in six (20.7%) of 29 eyes. Isolated foveoschisis was found in four eyes (13.8%). During follow-up, foveoschisis and VA worsened in 20 eyes and remained stable in nine. Ten of the 20 eyes that worsened had a premacular structure. A macular hole occurred in nine eyes, six of which had previously exhibited foveal detachment. Eleven eyes with foveoschisis underwent surgery, which improved VA significantly (P = .04, Wilcoxon test), but three eyes developed a macular hole.
  
  
  CONCLUSIONS
  MF may remain stable for many years without affecting VA. However, when it is combined with the presence of a premacular structure, the risk of a decrease in VA increases. When it is combined with foveal detachment, a macular hole seems to develop frequently, whether or not surgery is performed.
authors.affiliation: Assistance Publique-Hôpitaux de Paris, Hôpital Lariboisière, Service d'Ophtalmologie; Université Paris, France. david.gaucher@lrb.aphp.fr
authors.forename: David
authors.initials: D
authors.lastname: Gaucher
authors.forename: Belkacem
authors.initials: B
authors.lastname: Haouchine
authors.forename: Ramin
authors.initials: R
authors.lastname: Tadayoni
authors.forename: Pascale
authors.initials: P
authors.lastname: Massin
authors.forename: Ali
authors.initials: A
authors.lastname: Erginay
authors.forename: Nathanael
authors.initials: N
authors.lastname: Benhamou
authors.forename: Alain
authors.initials: A
authors.lastname: Gaudric
mesh_terms: D000328:Adult; D000368:Aged; D019773:Epiretinal Membrane / Q000209:etiology / Q000601:surgery; D005260:Female; D005500:Follow-Up Studies; D005584:Fovea Centralis / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008297:Male; D008875:Middle Aged; D047728:Myopia, Degenerative / Q000150:complications*; D012029:Refraction, Ocular; D012167:Retinal Perforations / Q000209:etiology / Q000601:surgery; D041441:Retinoschisis / Q000175:diagnosis* / Q000209:etiology / Q000601:surgery*; D012189:Retrospective Studies; D041623:Tomography, Optical Coherence; D016896:Treatment Outcome; D014792:Visual Acuity; D014821:Vitrectomy