The molecular characterization of serogroup C Neisseria meningitidis strains circulating in Beijing.
The aim of this study was to characterize the molecular features of serogroup C Neisseria meningitidis strains circulating in Beijing, China. Twenty out of 23 strains belonged to ST 4821. The causative serosubtype for meningococcal meningitis was P1.12-1,16-8. All of the strains expressed class 3 PorB protein. Among the five pulsed-field gel electrophoresis patterns observed, pattern III predominated.
Zhang
Tie-gang
TG
Institute of Immunization and Prevention, Beijing Center for Disease Prevention and Control. 16, Hepingli Middle Avenue, Dongcheng District, Beijing 100013, China. ztg628@sohu.com
He
Jing-guo
JG
He
Xiong
X
Chen
Li-juan
LJ
Shao
Zhu-jun
ZJ
Sun
Mei-ping
MP
D015373:Bacterial Typing Techniques; D002353:Carrier State / Q000453:epidemiology / Q000382:microbiology; D002681:China / Q000453:epidemiology; D016521:Electrophoresis, Gel, Pulsed-Field; D006801:Humans; D008585:Meningitis, Meningococcal / Q000453:epidemiology* / Q000382:microbiology*; D038542:Neisseria meningitidis, Serogroup C / Q000145:classification* / Q000235:genetics*; D017851:Phosphotransferases (Carboxyl Group Acceptor); D017422:Sequence Analysis, DNA; D012703:Serotyping
D017851:Phosphotransferases (Carboxyl Group Acceptor); C020650:glutamate 5-kinase