Screening for acute HIV infection: lessons learned.
Human immunodeficiency virus (HIV) nucleic acid testing is increasingly being used by researchers and public health screening programs to identify highly infectious, HIV antibody-negative individuals with acute HIV infection. We present cases to illustrate unusual instances of acute HIV screening, which include "window period" testing and the discovery of low-level HIV RNA.
Stekler
Joanne
J
Department of Medicine, University of Washington, Seattle, WA, USA. jstekler@u.washington.edu
Maenza
Janine
J
Stevens
Claire E
CE
Swenson
Paul D
PD
Coombs
Robert W
RW
Wood
Robert W
RW
Campbell
Mary S
MS
Nickle
David C
DC
Collier
Ann C
AC
Golden
Matthew R
MR
D000208:Acute Disease; D005188:False Negative Reactions; D006678:HIV / Q000302:isolation & purification; D015483:HIV Antibodies / Q000097:blood*; D015658:HIV Infections / Q000175:diagnosis* / Q000235:genetics; D018023:HIV Seronegativity; D006679:HIV Seropositivity; D006801:Humans; D008403:Mass Screening; D021141:Nucleic Acid Amplification Techniques / Q000379:methods; D012367:RNA, Viral / Q000097:blood*; D012680:Sensitivity and Specificity; D014766:Viremia / Q000175:diagnosis
D015483:HIV Antibodies; D012367:RNA, Viral