[Role of green tea in oxidative stress prevention].
OBJECTIVE
Oxidative stress is a condition caused by an increase of Reactive Oxygen Species (ROS) or by a shortage of the mechanisms of cellular protection and antioxidant defence. ROS have a potential oxidative effect towards various cellular macromolecules: proteins, nucleic acids, proteoglycans, lipids, with consequent damages in several cellular districts and promotion of the ageing process of the organism. However, some substances are able to prevent and/or reduce the damages caused by ROS; therefore, they are defined antioxidant. The present research studied, in a group of subjects, the antioxidant effects of the green tea, that was administered with fruit and vegetables in a strictly controlled diet.


METHODS
50 subjects were selected and requested to daily consume 2-3 fruit portions (especially pineapple), 3-5 portions of vegetables (especially tomato) and 2-3 glasses of green tea for about 2 months to integrate the controlled basic diet. Some indicators of the oxidative stress were measured in the plasma before and after the integration period.


RESULTS
The integration of a basic diet with supplements of fruit, vegetables and green tea turned out to be able in increasing both plasmatic total antioxidant capacity and endogenous antioxidant levels and to reduce the lipid peroxidation of the membranes, suggesting a reduction of the oxidative stress.


CONCLUSIONS
These data suggest that an adequate supplement of antioxidants can prevent oxidative stress and correlated pathologies.
Metro
D
D
Dipartimento di Scienze Biochimiche, Fisiologiche e della Nutrizione Università di Messina, Italia. dmetro@unime.it
Muraca
U
U
Manasseri
L
L
D000328:Adult; D000368:Aged; D000975:Antioxidants / Q000008:administration & dosage*; D004032:Diet; D005260:Female; D005638:Fruit; D006801:Humans; D008297:Male; D008875:Middle Aged; D018384:Oxidative Stress; D017382:Reactive Oxygen Species; D013482:Superoxide Dismutase / Q000097:blood; D013662:Tea; D014675:Vegetables; D014801:Vitamin A / Q000097:blood; D014810:Vitamin E / Q000097:blood
D000975:Antioxidants; D017382:Reactive Oxygen Species; D013662:Tea; D014801:Vitamin A; D014810:Vitamin E; D013482:Superoxide Dismutase