title: MR mammography is useful in the preoperative locoregional staging of breast carcinomas with extensive intraductal component.
abstract: OBJECTIVE
  To determine the role of magnetic resonance (MR) mammography in detection and assessment of extent of tumors with extensive intraductal component (EIC+).
  
  
  METHODS
  In a prospective study, 233 consecutive women with a suspicious lesion underwent preoperative MR mammography and 209 invasive ductal carcinomas were detected. We studied the prediction of intraductal spread on mammography (MX), ultrasound (US) and MR. We compared the size of the total lesion on MX, US and MR and correlated it with histopathology. Enhancement patterns on MR were described.
  
  
  RESULTS
  Of 209 invasive ductal carcinomas, 50 were EIC+ (24%). MX predicted intraductal spread in EIC+ carcinomas in 48.5%, US in 34.2% and MR in 68%. Compared to MX and US, MR was best in assessment of total tumor size. On MR, ductal spread in EIC+ tumors presented as ductal or linear enhancement, long spicules, a regional enhancing area or nodules adjacent to a mass.
  
  
  CONCLUSIONS
  MR had the highest sensitivity to predict intraductal spread and was superior in assessing total tumor size.
authors.affiliation: Department of Radiology, University Hospital Antwerp, Antwerp, Belgium. Mireille_Van_Goethem@hotmail.com
authors.forename: M
authors.initials: M
authors.lastname: Van Goethem
authors.forename: K
authors.initials: K
authors.lastname: Schelfout
authors.forename: E
authors.initials: E
authors.lastname: Kersschot
authors.forename: C
authors.initials: C
authors.lastname: Colpaert
authors.forename: I
authors.initials: I
authors.lastname: Verslegers
authors.forename: I
authors.initials: I
authors.lastname: Biltjes
authors.forename: W A
authors.initials: WA
authors.lastname: Tjalma
authors.forename: A
authors.initials: A
authors.lastname: De Schepper
authors.forename: J
authors.initials: J
authors.lastname: Weyler
authors.forename: P M
authors.initials: PM
authors.lastname: Parizel
mesh_terms: D000328:Adult; D000368:Aged; D001943:Breast Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D018270:Carcinoma, Ductal, Breast / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000556:secondary* / Q000601:surgery; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000556:secondary* / Q000601:surgery; D005260:Female; D006801:Humans; D007090:Image Interpretation, Computer-Assisted; D008279:Magnetic Resonance Imaging / Q000379:methods; D008327:Mammography / Q000379:methods; D015412:Mastectomy, Segmental; D008875:Middle Aged; D009367:Neoplasm Staging; D011237:Predictive Value of Tests; D015995:Prevalence; D011446:Prospective Studies; D012680:Sensitivity and Specificity; D016217:Ultrasonography, Mammary