Beta-aminoethyltrifluoroborates: efficient aminoethylations via Suzuki-Miyaura cross-coupling.
A set of phenethylamines has been successfully prepared via Suzuki-Miyaura cross-coupling of diverse potassium beta-aminoethyltrifluoroborates with aryl halides. The potassium beta-aminoethyltrifluoroborates were easily prepared via hydroboration of enamine and enamide precursors. [reaction: see text].
Molander
Gary A
GA
Roy and Diana Vagelos Laboratories, Department of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania 19104-6323, USA. gmolandr@sas.upenn.edu
Vargas
Fabricio
F
D000478:Alkylation; D001896:Boron Compounds / Q000737:chemistry*; D006846:Hydrocarbons, Halogenated / Q000737:chemistry; D015394:Molecular Structure; D010627:Phenethylamines / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
D001896:Boron Compounds; D006846:Hydrocarbons, Halogenated; D010627:Phenethylamines