title: Mitochondrial DNA in the oocyte and the developing embryo.
abstract: Mitochondria play a primary role in cellular energetic metabolism, homeostasis, and death. They possess their own multicopy genome, which is maternally transmitted. Mitochondria are directly involved at several levels in the reproductive process since their functional status influences the quality of oocytes and contributes to the process of fertilization and embryonic development. This chapter discusses recent findings concerning mitochondrial DNA content and its expression during oogenesis, fertilization, and early embryonic development.
authors.affiliation: INSERM U694, F-49033 Angers, France.
authors.forename: Pascale
authors.initials: P
authors.lastname: May-Panloup
authors.forename: Marie-Françoise
authors.initials: MF
authors.lastname: Chretien
authors.forename: Yves
authors.initials: Y
authors.lastname: Malthiery
authors.forename: Pascal
authors.initials: P
authors.lastname: Reynier
mesh_terms: D000818:Animals; D019069:Cell Respiration; D004272:DNA, Mitochondrial / Q000235:genetics*; D004622:Embryo, Mammalian / Q000196:embryology* / Q000378:metabolism*; D006801:Humans; D009154:Mutation / Q000235:genetics; D009865:Oocytes / Q000378:metabolism*; D014158:Transcription, Genetic / Q000235:genetics
chemical_list: D004272:DNA, Mitochondrial