Examination of the new alpha-(2'Z-fluoro)vinyl trigger with lysine decarboxylase: the absolute stereochemistry dictates the reaction course.
Karukurichi
Kannan R
KR
Department of Chemistry, University of Nebraska, Lincoln, Nebraska 68588-0304, USA.
de la Salud-Bea
Roberto
R
Jahng
Wan Jin
WJ
Berkowitz
David B
DB
D002262:Carboxy-Lyases / Q000737:chemistry*; D004789:Enzyme Activation; D004791:Enzyme Inhibitors / Q000138:chemical synthesis / Q000737:chemistry*; D020611:Hafnia alvei / Q000201:enzymology; D008239:Lysine / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy / Q000379:methods; D008968:Molecular Conformation; D012680:Sensitivity and Specificity; D013237:Stereoisomerism; D013329:Structure-Activity Relationship; D014753:Vinyl Compounds / Q000138:chemical synthesis / Q000737:chemistry*
D004791:Enzyme Inhibitors; C519017:L-2'-fluorovinyllysine; D014753:Vinyl Compounds; D002262:Carboxy-Lyases; C021520:lysine decarboxylase; D008239:Lysine