Recommendations to define exercise prescription for Duchenne muscular dystrophy.
Duchenne muscular dystrophy yields pervasive and progressive muscle weakness. This weakness may be attenuated by regular, low-intensity exercise. However, there is a critical lack of data to support appropriate exercise prescription. Because inappropriate activity may exacerbate the dystrophic process, a systematic analysis of muscle function to determine potential exercise load thresholds to avoid injury in dystrophic mice and dogs, and then in humans, is recommended.
Grange
Robert W
RW
Department of Human Nutrition, Foods and Exercise, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061-0430, USA. rgrange@vt.edu
Call
Jarrod A
JA
D000818:Animals; D005081:Exercise Therapy; D006801:Humans; D008297:Male; D020388:Muscular Dystrophy, Duchenne / Q000503:physiopathology / Q000534:rehabilitation*