Influence of motor symptoms upon the quality of life of patients with Parkinson's disease.
We studied the impact of various motor and nonmotor symptoms upon quality of life in patients with Parkinson's disease (PD). The study comprised 110 patients with PD (age: 68.6 years, course of the disease: 7.6 years). The Unified Parkinson Disease Rating Scale (UPDRS; I-IV) and Parkinson's Disease Questionnaire (PDQ-39) were recorded. We recorded the correlations between years of disease and UPDRS IV, as well as PDQ-39 and UPDRS I, II, III and IV. Introduction of all variables into a linear regression model showed that 3 variables accounted for 51% of the variance in PDQ-39. Mental condition, gait disorders and complications of dopaminergic drugs are the variables that most affect the quality of life of patients with PD.
Gómez-Esteban
J C
JC
Neurology Service, Movement Disorders Unit, Hospital of Cruces, Baracaldo, and Neurosciences Department, Basque Country University, Bilbao, Spain. jgomeze@meditex.es
Zarranz
J J
JJ
Lezcano
E
E
Tijero
B
B
Luna
A
A
Velasco
F
F
Rouco
I
I
Garamendi
I
I
D000368:Aged; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D016014:Linear Models; D008297:Male; D008875:Middle Aged; D009069:Movement Disorders / Q000209:etiology*; D010300:Parkinson Disease / Q000503:physiopathology* / Q000523:psychology*; D011788:Quality of Life; D012720:Severity of Illness Index; D018434:Sickness Impact Profile; D011795:Surveys and Questionnaires