Is the ability to identify deviations in multiple trajectories compromised by amblyopia?
Amblyopia results in a severe loss of positional information and in the ability to accurately enumerate objects (V. Sharma, D. M. Levi, & S. A. Klein, 2000). In this study, we asked whether amblyopia also disrupts the ability to track a near-threshold change in the trajectory of a single target amongst multiple similar potential targets. In the first experiment, we examined the precision for detecting a deviation in the linear motion trajectory of a dot by measuring deviation thresholds as a function of the number of moving trajectories (T). As in normal observers, we found that in both eyes of amblyopes, threshold increases steeply as T increases from 1 to 4. Surprisingly, for T = 1-4, thresholds were essentially identical in both eyes of the amblyopes and were similar to those of normal observers. In a second experiment, we measured the precision for detecting a deviation in the orientation of a static, bilinear "trajectory" by again measuring deviation thresholds (i.e., angle discrimination) as a function of the number of oriented line "trajectories" (T). Relative to the nonamblyopic eye, amblyopes show a marked threshold elevation for a static target when T = 1. However, thresholds increased with T with approximately the same slope as in their preferred eye and in the eyes of the normal controls. We conclude that while amblyopia disrupts static angle discrimination, amblyopic dynamic deviation detection thresholds are normal or very nearly so.
Levi
Dennis M
DM
School of Optometry and Helen Wills Neuroscience Institute, UC Berkeley, Berkeley, CA 94720-2020, USA. dlevi@berkeley.edu
Tripathy
Srimant P
SP
D000328:Adult; D000550:Amblyopia / Q000503:physiopathology* / Q000523:psychology; D001288:Attention; D004192:Discrimination, Psychological; D023882:Dominance, Ocular; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009039:Motion Perception; D009949:Orientation; D011698:Pursuit, Smooth; D012684:Sensory Thresholds