title: Intrasellar pressure and tumor volume in pituitary tumor: relation study.
abstract: OBJECTIVE
  To determine if there was a relationship between intrassellar pressure (ISP) and pituitary tumor volume.
  
  
  METHODS
  Between August 2002 and May 2004, 60 patients aged between 13 and 75 years old (39 males), having a pituitary adenoma were submitted to an endoscope transseptal approach. During the surgery and before tumor resection, 2 mm of the sellas floor were removed and a 1.5 mm dural opening made to place a transducer into the pituitary adenoma. The transducer was connected to a pressure monitor.
  
  
  RESULTS
  The intrasellar pressure, ranged from 2-51 mmHg and was measured based on the classification of Hardy-Vezina. The most elevated was in the type II macro adenomas with 32.6 mmHg, sharply superior to the value of a normal intracranial pressure.
  
  
  CONCLUSIONS
  These values showed that the macroadenomas confined to the sella, without destruction of the floor and integrity of the diaphragm, type II of Hardy-Vezina, presented a value of ISP much higher than intra-extrasellar macroadenoma's.
authors.affiliation: Neurosurgery Department General, Hospital of Fortaleza, Fortaleza, CE, Brazil. jagondim@secrel.com.br
authors.forename: Jackson A
authors.initials: JA
authors.lastname: Gondim
authors.forename: Osvaldo I
authors.initials: OI
authors.lastname: Tella
authors.forename: Michele
authors.initials: M
authors.lastname: Schops
mesh_terms: D000236:Adenoma / Q000473:pathology* / Q000503:physiopathology / Q000601:surgery; D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D007427:Intracranial Pressure; D008297:Male; D008875:Middle Aged; D010911:Pituitary Neoplasms / Q000473:pathology* / Q000503:physiopathology / Q000601:surgery; D011300:Preoperative Care; D012658:Sella Turcica / Q000503:physiopathology*; D014160:Transducers, Pressure