Epithelioid osteosarcoma presenting as a rapidly expanding maxillary mass.
BACKGROUND
Osteosarcomas of the jaws account for less than 10% of reported neoplasms of this type. Patients with osteosarcoma in this region tend to be in the late-third to mid-fourth decades of life. The osteoblastic, chondroblastic, and fibroblastic variants constitute the majority of lesions.


METHODS
A mass was observed in the maxilla of a 50-year-old male who presented for a complete odontectomy. Over the ensuing weeks, the mass substantially increased in size, despite multimodality treatment efforts.


RESULTS
Radiographic findings revealed a mixed density mass of the left maxilla. Histologic, immunohistochemical, and electron microscopy examination of the tumor showed a malignant mesenchymal neoplasm consisting of sheets of epithelioid and spindle cells exhibiting focal osteoid formation.


CONCLUSIONS
We report a rare and aggressive case of epithelioid osteosarcoma arising in the maxillofacial complex.
Rinaggio
Joseph
J
Department of Diagnostic Sciences, University of Medicine and Dentistry of New Jersey--New Jersey Dental School, Newark, New Jersey, USA. rinaggjo@umdnj.edu
Kewitt
Greg F
GF
McGuff
H Stan
HS
D015622:Epithelioid Cells / Q000473:pathology*; D017809:Fatal Outcome; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008441:Maxillary Neoplasms / Q000473:pathology*; D008854:Microscopy, Electron; D008875:Middle Aged; D012516:Osteosarcoma / Q000473:pathology*; D014057:Tomography, X-Ray Computed