Acute myocardial infarction with normal coronary arteries in a patient with Hodgkin's disease: a late complication of irradiation and chemotherapy.
We describe the case of a 31-year-old man who experienced an acute myocardial infarction 16 years after undergoing radiation and vinca alkaloid therapy for Hodgkin's disease. Even though coronary artery disease is a well-established complication after mediastinal radiation therapy, this adult patient had normal coronary angiographic results, with no traditional risk factors for coronary artery disease, and no hematologic or other abnormality associated with hypercoagulability.
Letsas
Konstantinos P
KP
Second Department of Cardiology, Evangelismos General Hospital of Athens, 10676 Athens, Greece.
Korantzopoulos
Panagiotis
P
Evangelou
Dimitrios
D
Pappas
Loukas K
LK
Kardaras
Fotis
F
D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D003131:Combined Modality Therapy / Q000009:adverse effects; D017023:Coronary Angiography; D003331:Coronary Vessels; D006689:Hodgkin Disease / Q000150:complications* / Q000628:therapy; D006801:Humans; D008297:Male; D009203:Myocardial Infarction / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000209:etiology*; D019851:Thrombophilia / Q000188:drug therapy / Q000209:etiology*