Expression and immunohistochemical localization of galectin-3 in various mouse tissues.
The expression and immunohistochemical localization of galectin-3, a beta-galactoside-binding protein, was studied in several mouse tissues. Galectin-3 expression was low in the cerebrum, heart, and pancreas, and moderate in the liver, ileum, kidney, and adrenal gland. High expression of galectin-3 was found in the lung, spleen, stomach, colon, uterus, and ovary. The results of Western blot analysis largely matched the immunohistochemical findings for galectin-3. These findings suggest that galectin-3 is differentially expressed in a variety of organs in the mouse. This study provides valuable information for research on galectin-3.
Kim
Heechul
H
Department of Veterinary Medicine, Cheju National University, Jeju 690-756, South Korea.
Lee
Jeeyoung
J
Hyun
Jin Won
JW
Park
Jae Woo
JW
Joo
Hong-gu
HG
Shin
Taekyun
T
D000818:Animals; D015153:Blotting, Western; D003106:Colon / Q000737:chemistry; D005260:Female; D037502:Galectin 3 / Q000032:analysis* / Q000235:genetics*; D020869:Gene Expression Profiling; D007150:Immunohistochemistry; D037102:Lectins / Q000378:metabolism; D008168:Lung / Q000737:chemistry; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D010053:Ovary / Q000737:chemistry; D013154:Spleen / Q000737:chemistry; D013270:Stomach / Q000737:chemistry; D014018:Tissue Distribution; D014599:Uterus / Q000737:chemistry
D037502:Galectin 3; D037102:Lectins