[Study on anti-tumor effect of medicinal fungi Phellinus igniarius extracts].
OBJECTIVE
To study the inhibiting effect of medicinal fungi Phellinus igniarius extracts on S180 tumor and the immunoregulation effect on the S180-induced tumor mice.


METHODS
S180 mice were orally given 100, 200, 400 mg x kg(-1) dosage of P. igniarius extracts, then the inhibition grow effect, spleen index, and thyme index were measured.


RESULTS
Medicinal fungi P. igniarius extracts can increase the spleen index and thyme index and the inhibiting tumor rate was 31.88%, 46.25%, 53.13%, respectively. Also, medicinal fungi P. igniarius extracts can prolong life in mice.


CONCLUSIONS
The medicinal fungi P. igniarius extracts show obviously anti-tumor effect and immunoregulation effect.
Yang
Quan
Q
School of Chinese Medicine, Guangdong Parmaceutical University, Guangzhou 510006, China. yangquan7208@vip.163.com
Hu
Xu-Guang
XG
Wan
Qi
Q
Wang
Wen-Quan
WQ
D000818:Animals; D000970:Antineoplastic Agents / Q000302:isolation & purification / Q000494:pharmacology*; D051379:Mice; D009368:Neoplasm Transplantation; D011124:Polyporaceae / Q000737:chemistry; D011134:Polysaccharides / Q000302:isolation & purification / Q000494:pharmacology*; D012510:Sarcoma 180 / Q000473:pathology*; D013154:Spleen / Q000473:pathology; D013950:Thymus Gland / Q000473:pathology
D000970:Antineoplastic Agents; D011134:Polysaccharides