title: The diagnostic value of PET-CT for peritoneal dissemination of abdominal malignancies.
abstract: OBJECTIVE
  To evaluate the diagnostic value of PET-CT for predicting peritoneal metastasis of abdominal malignancies.
  
  
  METHODS
  One hundred fifty four (154) cases of malignant tumor, including 141 cases of gastric cancer, 9 cases of colon cancer, 2 cases of ovary cancer, and 2 cases of pseudomyxoma, had accepted PET CT from Nov. 2002 to Jan. 2006. One hundred twenty three (123) had also accepted high speed spiral CT (HSSCT) as control. The results were compared with peritoneal lavage, pathological examination and clinical manifestation.
  
  
  RESULTS
  The accuracy of PET-CT for peritoneal metastasis was 87.7%, with sensitivity 72.7%, specificity 93.6%, PPV 82.1% and NPV 89.6%. HSSCT showed an accuracy of 79.7%, sensitivity 47.4%, specificity 94.1%, PPV 78.3%, and NPV 80.0%. PET-CT had significantly better sensitivity than HSSCT (p < 0.05). For gastric cancer patients alone, PET CT had an accuracy of 87.9%, sensitivity 74.4%, specificity 93.1%, PPV 80.6% and NPV 90.5%, significantly better than HSSCT's 78.1, 39.4, 93.8, 72.2, and 79.2% (p < 0.01), respectively. In case of Cy1P0, PET-CT showed a seemingly better sensitivity of 53.3% vs. 13.3% of HSSCT, although not statistically significant because of the number of observations (p = 0.053). And in P1 cases, PET-CT and HSSCT manifested sensitivity of 84.2% vs 63.2%, respectively, without significance (p = 0.141).
  
  
  CONCLUSIONS
  PET-CT is useful in predicting peritoneal metastasis of malignancies.
authors.affiliation: Dept. of Gastric Surgery, and Peritoneal Dissemination, Shizuoka Cancer Center, Japan.
authors.forename: Qiu-Meng
authors.initials: QM
authors.lastname: Yang
authors.forename: Etsuro
authors.initials: E
authors.lastname: Bando
authors.forename: Taiichi
authors.initials: T
authors.lastname: Kawamura
authors.forename: Gorou
authors.initials: G
authors.lastname: Tsukiyama
authors.forename: Masayuki
authors.initials: M
authors.lastname: Nemoto
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Yonemura
authors.forename: Hiroyoshi
authors.initials: H
authors.lastname: Furukawa
mesh_terms: D000008:Abdominal Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology*; D000328:Adult; D000368:Aged; D003110:Colonic Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology; D005260:Female; D006801:Humans; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology; D010529:Peritoneal Cavity; D010534:Peritoneal Neoplasms / Q000000981:diagnostic imaging* / Q000556:secondary*; D049268:Positron-Emission Tomography; D011553:Pseudomyxoma Peritonei / Q000000981:diagnostic imaging; D012680:Sensitivity and Specificity; D013274:Stomach Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology; D014057:Tomography, X-Ray Computed