title: IFNgamma: issuing macrophages a license to kill.
abstract: T cells tell macrophages when to start making the toxic soup of lysosomal enzymes, reactive oxygen species, and nitric oxide that destroys intracellular pathogens. In 1983, Carl Nathan proved that this start signal comes in the form of the secreted cytokine IFNgamma.
authors.affiliation: hbashyam@rockefeller.edu
authors.forename: Hema
authors.initials: H
authors.lastname: Bashyam
mesh_terms: D000818:Animals; D003602:Cytotoxicity, Immunologic; D049673:History, 20th Century; D006801:Humans; D007371:Interferon-gamma / Q000266:history*; D008262:Macrophage Activation; D008264:Macrophages / Q000276:immunology*; D013601:T-Lymphocytes / Q000276:immunology
chemical_list: D007371:Interferon-gamma