title: [Effects of ligustrazine injection on lymph circulation in rats with acute microcirculation disturbance].
abstract: OBJECTIVE
  To explore the interferential effect of ligustrazine injection (LI) on lymph circulation in rats with acute microcirculation disturbance (AMD).
  
  
  METHODS
  Sixteen Wistar male rats were divided into experimental and control groups. AMD was done by Dextran 500 injection from jugular vein and effects of LI on lymph circulation were observed in these rats by lymphatology methods.
  
  
  RESULTS
  During AMD phase, the contractility of mesenteric lymphatic (ML) , the intestinal lymph flux, lymphocytes out put were obviously decreased, and there was little monocytes in the lymph fluid, but the lymph fluid viscosity was increased. After treatment of LI, the contractility of ML, the intestinal lymph flux, lymphocytes out put was obvious increased. There was a lot of monocytes in the lymph fluid and the lymph fluid viscosity was decreased. There were signifcant difference compared with control group (P < 0.05).
  
  
  CONCLUSIONS
  LI can influence the recovery of AMD though enhancing the contractility of ML and the transport function of lymph circulation and decreasing lymph fluid viscosity.
authors.affiliation: Hebei North College, Zhangjiakou 075029, China. liuyk88@sina.com
authors.forename: Yan-kai
authors.initials: YK
authors.lastname: Liu
authors.forename: Chun-yu
authors.initials: CY
authors.lastname: Niu
authors.forename: Zi-gang
authors.initials: ZG
authors.lastname: Zhao
authors.forename: Yu-ping
authors.initials: YP
authors.lastname: Zhang
authors.forename: Shu-ting
authors.initials: ST
authors.lastname: Du
authors.forename: Hua
authors.initials: H
authors.lastname: Jiang
mesh_terms: D000208:Acute Disease; D000818:Animals; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage / Q000494:pharmacology*; D007267:Injections; D008208:Lymphatic System / Q000098:blood supply* / Q000187:drug effects*; D008214:Lymphocytes / Q000187:drug effects; D008297:Male; D008643:Mesentery / Q000098:blood supply / Q000187:drug effects; D008833:Microcirculation / Q000187:drug effects; D009000:Monocytes / Q000187:drug effects; D010946:Plants, Medicinal / Q000737:chemistry; D011719:Pyrazines / Q000494:pharmacology*; D051381:Rats; D017208:Rats, Wistar
chemical_list: D004365:Drugs, Chinese Herbal; D011719:Pyrazines; C017953:tetramethylpyrazine