Autonomic nervous system activity in the late luteal phase of eumenorrheic women with premenstrual symptomatology.
The majority of women of reproductive age experience a regular recurrence of various symptoms in the premenstrual phase. The etiopathogenesis of premenstrual symptomatology, however, remains inconclusive. The present study was proposed to evaluate whether the activity of the autonomic nervous system (ANS), which largely contributes to the relative stability of a human's internal environment, is altered during the menstrual cycle of women with premenstrual symptomatology. Thirty eumenorrheic young women participated in this study. All subjects were investigated during the follicular and late luteal phases. The ANS activity was assessed by means of heart rate variability power spectral analysis during supine rest. No intramenstrual cycle differences in the ANS activity were found in women experiencing no or small increases in premenstrual symptoms. In contrast, the sympathetic nervous system (SNS) activity significantly increased and the parasympathetic nervous system (PNS) activity apparently decreased in the late luteal phase in subjects whose premenstrual symptomatology was not unbearable, but substantially increased (> 20%) compared to the symptom-free follicular phase. The women with greater degrees of premenstrual distress possessed higher SNS activity and lower PNS activity in the late luteal phase than the women with less symptomatology. The ANS activity in the follicular phase did not differ among the subjects regardless of their premenstrual symptoms. Although causes and consequences continue to elude, the present study provides additional intriguing evidence that the altered functioning of ANS in the late luteal phase could be associated with diverse psychosomatic or behavioral symptoms appearing premenstrually.
Matsumoto
Tamaki
T
Department of Health Science, International Buddhist University, Osaka, Japan. tamaki@mail.shitennoji.ac.jp
Ushiroyama
Takahisa
T
Morimura
Mina
M
Moritani
Toshio
T
Hayashi
Tatsuya
T
Suzuki
Takashi
T
Tatsumi
Noriyuki
N
D000328:Adult; D000704:Analysis of Variance; D001341:Autonomic Nervous System / Q000502:physiology / Q000503:physiopathology*; D004562:Electrocardiography / Q000379:methods; D005260:Female; D005498:Follicular Phase / Q000502:physiology; D006339:Heart Rate / Q000502:physiology; D006801:Humans; D008183:Luteal Phase / Q000502:physiology; D008597:Menstrual Cycle / Q000502:physiology; D010275:Parasympathetic Nervous System / Q000502:physiology; D011293:Premenstrual Syndrome / Q000503:physiopathology*; D012146:Rest / Q000502:physiology; D012720:Severity of Illness Index; D011795:Surveys and Questionnaires