Proteomics and systems biology in exercise and sport sciences research.
A systems biology approach toward biological research seeks to model all concurrent processes in a cell, tissue, or organism by global measurements. In this review, we describe recent advances in mass spectrometry-based proteomics and their application toward interpreting the physiological adaptations of skeletal muscle with exercise and obesity.
Hittel
Dustin S
DS
Research Center for Genetic Medicine, Children's National Medical Center, George Washington University, Washington, DC 20010, USA. dhittel@cnmcresearch.org
Hathout
Yetrib
Y
Hoffman
Eric P
EP
D035843:Biomedical Research; D006801:Humans; D013058:Mass Spectrometry; D018482:Muscle, Skeletal / Q000502:physiology*; D040901:Proteomics; D013178:Sports Medicine; D049490:Systems Biology