title: Increasing incidence of sterile-site infections due to non-multidrug-resistant, oxacillin-resistant Staphylococcus aureus among hospitalized patients.
abstract: The incidence of community-associated, healthcare-associated, and hospital-acquired sterile-site infections due to methicillin-resistant Staphylococcus aureus (MRSA) isolates and the susceptibility of the isolates to non- beta -lactam antibiotics were evaluated for 549 hospitalized patients during a 3-year period. The incidence of community-associated MRSA infection increased significantly. The annual percentage of MRSA isolates from cases of healthcare-associated and hospital-acquired infection that were susceptible to 3 or more non- beta -lactam antibiotics increased significantly.
authors.affiliation: Department of Pharmacy, Barnes-Jewish Hospital, St. Louis, MO 63110, USA.
authors.forename: Garrett E
authors.initials: GE
authors.lastname: Schramm
authors.forename: Jennifer A
authors.initials: JA
authors.lastname: Johnson
authors.forename: Joshua A
authors.initials: JA
authors.lastname: Doherty
authors.forename: Scott T
authors.initials: ST
authors.lastname: Micek
authors.forename: Marin H
authors.initials: MH
authors.lastname: Kollef
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D017714:Community-Acquired Infections / Q000453:epidemiology* / Q000382:microbiology; D003428:Cross Infection / Q000453:epidemiology / Q000382:microbiology; D006760:Hospitalization; D006801:Humans; D015994:Incidence; D016106:Methicillin Resistance; D010068:Oxacillin / Q000494:pharmacology*; D013203:Staphylococcal Infections / Q000453:epidemiology* / Q000382:microbiology; D013211:Staphylococcus aureus / Q000187:drug effects*
chemical_list: D000900:Anti-Bacterial Agents; D010068:Oxacillin