title: [The combined treatment of juvenile outset recurrent respiratory papillomatosis].
abstract: OBJECTIVE
  To explore the effective treatment of juvenile outset recurrent respiratory papillomatosis (JO-RRP).
  
  
  METHODS
  Thirty six patients of JO-RRP from 1993 to 2004 were analyzed retrospectively. Twenty seven patients were underwent laser excision by laryngoscope and nine patients were underwent laser excision through laryngostomy. Twenty eight patients who recurrenced more than two times in one year or involved extent of disease more than two anatomical subregion were give interferon after operation one week in addition.
  
  
  RESULTS
  All patients had normal deglutition, 28 cases (77.8%) had been succeed in decannulation. The complications included hoarseness in 8 cases, laryngeal stenosis in 6 cases and pulmonary infection in 3 cases.
  
  
  CONCLUSIONS
  The laser surgery by larynoscope and laryngostomy are two kinds of effective treatments for JO-RRP. The interferon therapy after the operation can restrain the recrudescence effectively.
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, Shanghai First People's Hospital, Shanghai 200080, China. lancet11@yahoo.com.cn
authors.forename: Jin
authors.initials: J
authors.lastname: Xie
authors.forename: Pin
authors.initials: P
authors.lastname: Dong
authors.forename: Keyong
authors.initials: K
authors.lastname: Li
authors.forename: Jie
authors.initials: J
authors.lastname: Wang
authors.forename: Bin
authors.initials: B
authors.lastname: Jin
authors.forename: Jia
authors.initials: J
authors.lastname: Zhang
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D007372:Interferons / Q000627:therapeutic use; D053685:Laser Therapy; D008297:Male; D009364:Neoplasm Recurrence, Local / Q000628:therapy*; D010212:Papilloma / Q000473:pathology / Q000628:therapy*; D012142:Respiratory Tract Neoplasms / Q000473:pathology / Q000628:therapy*; D012189:Retrospective Studies
chemical_list: D007372:Interferons