Subepidermal calcified nodule in a 7-month-old boy.
A 7-month-old healthy white boy presented for evaluation of a papule on his right ear. His mother reported a small cut-like lesion at this site shortly after birth that had gradually grown over time. The patient was born full term via repeat cesarean section. On physical examination, located on the right superior helix, there was a 5-6 mm, pink, firm papule with a rough scaly surface and peripheral erythema (Figure 1). The lesion was shave excised and sent for histologic analysis. Microscopic examination revealed a defect of the epidermis with underlying fibrin deposits (Figure 2). Subjacent to the ulcer, there was chondroid tissue, granulation tissue with prominent vascularity, and an extensive amount of amorphous calcified material throughout the dermis extending to the base of the specimen (Figure 3). The clinical and pathologic findings were consistent with a subepidermal calcified nodule (SCN), an uncommon idiopathic calcinosis. The lesion was surgically removed with good results.
Xu
Yaohui
Y
Section of Dermatology, Department of Medicine, University of Chicago Hospitals, Chicago, IL 60637, SUA.
Petronic-Rosic
Vesna
V
Stein
Sarah L
SL
D002114:Calcinosis / Q000473:pathology*; D004431:Ear, External; D006801:Humans; D007223:Infant; D008297:Male; D012871:Skin Diseases / Q000473:pathology*