[The combined treatment of juvenile outset recurrent respiratory papillomatosis].
OBJECTIVE
To explore the effective treatment of juvenile outset recurrent respiratory papillomatosis (JO-RRP).


METHODS
Thirty six patients of JO-RRP from 1993 to 2004 were analyzed retrospectively. Twenty seven patients were underwent laser excision by laryngoscope and nine patients were underwent laser excision through laryngostomy. Twenty eight patients who recurrenced more than two times in one year or involved extent of disease more than two anatomical subregion were give interferon after operation one week in addition.


RESULTS
All patients had normal deglutition, 28 cases (77.8%) had been succeed in decannulation. The complications included hoarseness in 8 cases, laryngeal stenosis in 6 cases and pulmonary infection in 3 cases.


CONCLUSIONS
The laser surgery by larynoscope and laryngostomy are two kinds of effective treatments for JO-RRP. The interferon therapy after the operation can restrain the recrudescence effectively.
Xie
Jin
J
Department of Otolaryngology-Head and Neck Surgery, Shanghai First People's Hospital, Shanghai 200080, China. lancet11@yahoo.com.cn
Dong
Pin
P
Li
Keyong
K
Wang
Jie
J
Jin
Bin
B
Zhang
Jia
J
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D007372:Interferons / Q000627:therapeutic use; D053685:Laser Therapy; D008297:Male; D009364:Neoplasm Recurrence, Local / Q000628:therapy*; D010212:Papilloma / Q000473:pathology / Q000628:therapy*; D012142:Respiratory Tract Neoplasms / Q000473:pathology / Q000628:therapy*; D012189:Retrospective Studies
D007372:Interferons