Synthesis and antigenotoxic activity of some naphtho[2,1-b]pyrano[3,2-e][1,2,4]triazolo[1,5-c]pyrimidine derivatives.
In this study, some pyranotriazolopyrimidine derivatives were synthesised by reacting ethoxymethyleneamino derivatives with hydrazides. Their structures were elucidated by IR, (1)H NMR, and (13)C NMR spectroscopic data and elemental analyses. Antigenotoxic activity of the obtained compounds was tested in Escherichia coli PQ37 by using the SOS chromotest.
Chabchoub
Fakher
F
Laboratoire de Chimie Appliquée: Hétérocycles, Corps Gras et Polymères, Faculté des Sciences de Sfax, Sfax, Tunisia.
Messaâd
Mehdi
M
Ben Mansour
Hédi
H
Chekir-Ghedira
Leila
L
Salem
Mansour
M
D016587:Antimutagenic Agents / Q000138:chemical synthesis* / Q000494:pharmacology*; D004926:Escherichia coli / Q000187:drug effects; D009682:Magnetic Resonance Spectroscopy; D011743:Pyrimidines / Q000138:chemical synthesis* / Q000494:pharmacology*; D013055:Spectrophotometry, Infrared
D016587:Antimutagenic Agents; D011743:Pyrimidines