title: Evaluation of a novel enzyme-linked immunosorbent assay to detect immunoglobulin G antibody to enolase for serodiagnosis of invasive candidiasis.
abstract: The performance of a new test to detect antibodies to Candida albicans recombinant enolase was investigated in 47 immunocompromised and 51 immunocompetent patients. The sensitivity, specificity, and positive and negative predictive values of the test for the diagnosis of invasive candidiasis were 81.0, 83.9, 79.1, and 85.5%, respectively.
authors.affiliation: Departamento de Inmunología, Microbiología y Parasitología, Facultad de Medicina y Odontología, Universidad del País Vasco, Apartado 699, E-48080 Bilbao, Vizcaya, Spain.
authors.forename: Ana
authors.initials: A
authors.lastname: Laín
authors.forename: María D
authors.initials: MD
authors.lastname: Moragues
authors.forename: Juan Carlos García
authors.initials: JC
authors.lastname: Ruiz
authors.forename: Joaquín
authors.initials: J
authors.lastname: Mendoza
authors.forename: Ana
authors.initials: A
authors.lastname: Camacho
authors.forename: Amalia
authors.initials: A
authors.lastname: Del Palacio
authors.forename: José
authors.initials: J
authors.lastname: Pontón
mesh_terms: D000328:Adult; D000908:Antibodies, Fungal / Q000097:blood*; D002176:Candida albicans / Q000276:immunology*; D002177:Candidiasis / Q000175:diagnosis*; D004797:Enzyme-Linked Immunosorbent Assay / Q000379:methods*; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood*; D010751:Phosphopyruvate Hydratase / Q000276:immunology*; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D012698:Serologic Tests
chemical_list: D000908:Antibodies, Fungal; D007074:Immunoglobulin G; D010751:Phosphopyruvate Hydratase