title: Expression and immunohistochemical localization of galectin-3 in various mouse tissues.
abstract: The expression and immunohistochemical localization of galectin-3, a beta-galactoside-binding protein, was studied in several mouse tissues. Galectin-3 expression was low in the cerebrum, heart, and pancreas, and moderate in the liver, ileum, kidney, and adrenal gland. High expression of galectin-3 was found in the lung, spleen, stomach, colon, uterus, and ovary. The results of Western blot analysis largely matched the immunohistochemical findings for galectin-3. These findings suggest that galectin-3 is differentially expressed in a variety of organs in the mouse. This study provides valuable information for research on galectin-3.
authors.affiliation: Department of Veterinary Medicine, Cheju National University, Jeju 690-756, South Korea.
authors.forename: Heechul
authors.initials: H
authors.lastname: Kim
authors.forename: Jeeyoung
authors.initials: J
authors.lastname: Lee
authors.forename: Jin Won
authors.initials: JW
authors.lastname: Hyun
authors.forename: Jae Woo
authors.initials: JW
authors.lastname: Park
authors.forename: Hong-gu
authors.initials: HG
authors.lastname: Joo
authors.forename: Taekyun
authors.initials: T
authors.lastname: Shin
mesh_terms: D000818:Animals; D015153:Blotting, Western; D003106:Colon / Q000737:chemistry; D005260:Female; D037502:Galectin 3 / Q000032:analysis* / Q000235:genetics*; D020869:Gene Expression Profiling; D007150:Immunohistochemistry; D037102:Lectins / Q000378:metabolism; D008168:Lung / Q000737:chemistry; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D010053:Ovary / Q000737:chemistry; D013154:Spleen / Q000737:chemistry; D013270:Stomach / Q000737:chemistry; D014018:Tissue Distribution; D014599:Uterus / Q000737:chemistry
chemical_list: D037502:Galectin 3; D037102:Lectins