sHLA-G expression: is it really worth measuring?
HLA-G is believed to play a pivotal role in the immunoprotection of the semiallogenic embryo. Its expression during pre- and early implantation is correlated with the cleavage rate of the embryo. Studies in congenic mice have revealed that mRNA of both the maternal and paternal haplotypes are present in zygotes and in embryos at all stages of development.
Sher
G
G
Sher Institute for Reproductive Medicine, Las Vegas, NV 89109, USA. geoffreys@sherinstitute.com
Keskintepe
L
L
Ginsburg
M
M
D000328:Adult; D000818:Animals; D004622:Embryo, Mammalian / Q000276:immunology* / Q000378:metabolism; D005260:Female; D006680:HLA Antigens / Q000096:biosynthesis* / Q000235:genetics; D059951:HLA-G Antigens; D015395:Histocompatibility Antigens Class I / Q000096:biosynthesis* / Q000235:genetics; D006801:Humans; D051379:Mice; D011247:Pregnancy; D018873:Pregnancy Rate; D012333:RNA, Messenger / Q000378:metabolism
D006680:HLA Antigens; D059951:HLA-G Antigens; D015395:Histocompatibility Antigens Class I; D012333:RNA, Messenger