title: Flow analysis of left internal thoracic artery in myocardial revascularization surgery using y graft.
abstract: In order to evaluate the left internal thoracic artery flow pattern, when the vessel is used as a graft to supply the left coronary artery system, we evaluated flow by Doppler measurement, both at rest and under dobutamine stress. There were 2 groups of 20 patients each: group A patients received only a left internal thoracic artery graft to the left anterior descending artery, and group B patients received a pedicled left internal thoracic artery graft associated with a vein graft, which together supplied the left anterior descending artery and another branch of the left coronary artery. Angiography showed patent grafts in all patients from both groups. The following characteristics were evaluated: systolic flow, diastolic flow, total flow, total flow under stress/total flow at rest ratio, systolic peak velocity, diastolic peak velocity, and systolic peak velocity/diastolic peak velocity ratio. In group A, the total flow was 45.5 +/- 21.6 mL/min at rest and 68.3 +/- 32.9 mL/min under stress. In group B, the total flow was 98.2 +/- 50.4 mL/min at rest and 175.7 +/- 79.2 mL/min under stress. Comparison between groups showed a total flow increase in group B of 115.8% (P=0.0002) at rest and 157.2% (P <0.0001) under stress. The other characteristics were also statistically significant, except systolic flow, total flow under stress/total flow at rest ratio, and systolic peak velocity. Our results showed that the left internal thoracic artery sufficiently supplies regional myocardium at rest and during exercise (stress), demonstrating its great adaptability in response to demand.
authors.affiliation: Department of Heart Surgery of the Institute of Heart and Lung-ICORP, 60115280 Fortaleza, Ceará, Brazil. glaucolobo@uol.com.br
authors.forename: José G Lobo
authors.initials: JG
authors.lastname: Filho
authors.forename: Maria C A
authors.initials: MC
authors.lastname: Leitão
authors.forename: Antonio J V
authors.initials: AJ
authors.lastname: Forte
authors.forename: Heraldo G Lobo
authors.initials: HG
authors.lastname: Filho
authors.forename: André A
authors.initials: AA
authors.lastname: Silva
authors.forename: Eduardo S
authors.initials: ES
authors.lastname: Bastos
authors.forename: Henrique
authors.initials: H
authors.lastname: Murad
mesh_terms: D000328:Adult; D000368:Aged; D001783:Blood Flow Velocity; D017023:Coronary Angiography; D001026:Coronary Artery Bypass; D003326:Coronary Circulation; D023921:Coronary Stenosis / Q000000981:diagnostic imaging / Q000503:physiopathology* / Q000601:surgery; D003331:Coronary Vessels / Q000503:physiopathology*; D006321:Heart / Q000503:physiopathology; D006801:Humans; D008875:Middle Aged; D011446:Prospective Studies; D019737:Transplants