Constituents of the Egyptian Centaurea scoparia; Chlorinated Guaianolides of the Aerial Parts.
A new chlorine-containing guaianolide, chloroscoparin, was isolated from the ethanol extract of the aerial parts of CENTAUREA SCOPARIA Sieb. together with three known chlorine-containing guaianolides. The structures of the isolated compounds were elucidated by spectroscopic methods including (1)H-NMR-, 2D (1)H- (1)H COSY-, (13)C-NMR-, APT-, DEPT-, HETCOR-, long-range-HETCOR-, 2D INADEQUATE-, and mass spectra. The relative configuration was determined by 2D-NOESY studies. New NMR data for the known compounds are reported.
Youssef
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Pharmazeutisches Institut der Universitát, Hermann-Herder-Str. 9, D-79104 Freiburg i.Br., Federal Republic of Germany.
Frahm
A W
AW