Vascular endothelium summary statement VI: Research directions for the 21st century.
Effective translation of research advances from the bench to clinical and public health practice at the bedside and in the community at large represents an important step in the health research discovery enterprise. Increasingly, the gap in translating these advances into practice is being recognized. Successfully addressing this translational gap for the prevention and control of chronic diseases will require the development of novel, innovative, and, if necessary, nontraditional approaches. Participants in the 8th International Conference on Vascular Endothelium discussed a variety of novel approaches that have significant promise. Three of these approaches-vaccine development, genomics and proteomics, and tissue engineering-are highlighted in this position statement and strategies for public health practice and research are suggested.
Mensah
George A
GA
National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, (CDC), Mailstop K-40, 4770 Buford Highway NE, Atlanta, GA 30341-3717, USA. GMensah@cdc.gov
Catravas
John D
JD
Engelgau
Michael M
MM
Hooper
W Craig
WC
Madeddu
Paolo
P
Ryan
Una S
US
She
Jin-Xiong
JX
Reed
Eddie
E
Vinicor
Frank
F
Yacoub
Magdi H
MH
D000818:Animals; D035843:Biomedical Research / Q000639:trends*; D002318:Cardiovascular Diseases / Q000503:physiopathology / Q000517:prevention & control; D002908:Chronic Disease; D003920:Diabetes Mellitus / Q000503:physiopathology / Q000517:prevention & control; D004059:Diffusion of Innovation; D004730:Endothelium, Vascular / Q000503:physiopathology*; D023281:Genomics / Q000639:trends; D006801:Humans; D009369:Neoplasms / Q000503:physiopathology / Q000517:prevention & control; D009765:Obesity / Q000503:physiopathology / Q000517:prevention & control; D011322:Primary Prevention / Q000639:trends*; D040901:Proteomics / Q000639:trends; D015980:Public Health Practice; D023822:Tissue Engineering / Q000639:trends; D014611:Vaccination / Q000639:trends