[Hormonal contraception interactions].
OBJECTIVE
The purpose of this article is to discuss the probable ways of interactions between some drugs or remedies and steroid contraceptives.


METHODS
A review article.


METHODS
OBGYN Clinic of the 1t Faculty of Medicine, Prague, Teaching Hospital Bulovka.


METHODS
Low dose oral contraceptives are very popular these days. Some drugs and remedies could negatively influence the levels of ethinyl estradiol (EE) and/or progestins and thus increase the possibility of their failure. These drugs mostly implicate as an inducer of the CYP450 system (liver) and as an inducer of P-glycoprotein transport system (transmembrane drug pump in the intestines). We wanted to describe briefly the mechanism and the principles of their impact.
Hurt
K
K
OBGYN Clinic of the 1st Faculty of Medicine, Prague, Teaching Hospital, Bulovka.
Sottner
J
J
Záhumenský
J
J
Halaska
M
M
Krcmár
M
M
Krajcová
A
A
D003278:Contraceptives, Oral, Hormonal / Q000493:pharmacokinetics*; D004347:Drug Interactions; D005260:Female; D006801:Humans
D003278:Contraceptives, Oral, Hormonal