title: [Study on anti-tumor effect of medicinal fungi Phellinus igniarius extracts].
abstract: OBJECTIVE
  To study the inhibiting effect of medicinal fungi Phellinus igniarius extracts on S180 tumor and the immunoregulation effect on the S180-induced tumor mice.
  
  
  METHODS
  S180 mice were orally given 100, 200, 400 mg x kg(-1) dosage of P. igniarius extracts, then the inhibition grow effect, spleen index, and thyme index were measured.
  
  
  RESULTS
  Medicinal fungi P. igniarius extracts can increase the spleen index and thyme index and the inhibiting tumor rate was 31.88%, 46.25%, 53.13%, respectively. Also, medicinal fungi P. igniarius extracts can prolong life in mice.
  
  
  CONCLUSIONS
  The medicinal fungi P. igniarius extracts show obviously anti-tumor effect and immunoregulation effect.
authors.affiliation: School of Chinese Medicine, Guangdong Parmaceutical University, Guangzhou 510006, China. yangquan7208@vip.163.com
authors.forename: Quan
authors.initials: Q
authors.lastname: Yang
authors.forename: Xu-Guang
authors.initials: XG
authors.lastname: Hu
authors.forename: Qi
authors.initials: Q
authors.lastname: Wan
authors.forename: Wen-Quan
authors.initials: WQ
authors.lastname: Wang
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000302:isolation & purification / Q000494:pharmacology*; D051379:Mice; D009368:Neoplasm Transplantation; D011124:Polyporaceae / Q000737:chemistry; D011134:Polysaccharides / Q000302:isolation & purification / Q000494:pharmacology*; D012510:Sarcoma 180 / Q000473:pathology*; D013154:Spleen / Q000473:pathology; D013950:Thymus Gland / Q000473:pathology
chemical_list: D000970:Antineoplastic Agents; D011134:Polysaccharides