[Effect of overload environment on IGF-1 expression of osteoblasts].
In the study of the relationship between cells overloading and the formation, regeneration and growth of bone, the text discussed osteoblasts express IGF-1 variation under overloading environment. The research of overloading on cellular level may elucidate the mechanical effect on the formation, regeneration and growth of bone and the mechanism of cell response in bone.
Shang
Juanfang
J
Key Lab. of Biomechanics & Tissue Engineering under the State Ministry of Education, College of Bioengineering, Chongqing University, Chongqing 400044, China.
Tang
Liling
L
Niu
Xufeng
X
Wang
Yuanliang
Y
D000818:Animals; D006801:Humans; D007334:Insulin-Like Growth Factor I / Q000096:biosynthesis* / Q000235:genetics; D010006:Osteoblasts / Q000166:cytology / Q000378:metabolism*; D010012:Osteogenesis; D012333:RNA, Messenger / Q000096:biosynthesis / Q000235:genetics; D013314:Stress, Mechanical; D016474:Weight-Bearing / Q000502:physiology*
D012333:RNA, Messenger; D007334:Insulin-Like Growth Factor I