Drug related crisis in myasthenia gravis.
Myasthenia gravis is an autoimmune disorder where antibodies against the nicotinic Ach receptor resulting in impaired transmission at the NM junction. A number of drugs have been reported to cause neuromuscular blockade and/or to increase weakness in myasthenia gravis. We report a case of myasthenia gravis in which the calcium channel blocker-nifedipine caused the worsening of the symptoms.
Rajasekaran
D
D
Department of Medicne, Stanley Medical College and Hospital, Chennai.
Chandrasekar
S
S
Rajendran
M
M
D000328:Adult; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000627:therapeutic use; D002121:Calcium Channel Blockers / Q000009:adverse effects*; D006801:Humans; D008297:Male; D009157:Myasthenia Gravis / Q000188:drug therapy*; D009543:Nifedipine / Q000009:adverse effects*
D000806:Angiotensin-Converting Enzyme Inhibitors; D002121:Calcium Channel Blockers; D009543:Nifedipine