The concomitant crystallization of two polymorphs of 1-deoxy-alpha-D-tagatose.
The crystalline form of 1-deoxy-D-tagatose, C6H12O5, is shown to be 1-deoxy-alpha-D-tagatopyranose; the absolute configuration is determined by use of D-lyxono-1,4-lactone as the starting material. The title compound crystallized as concomitant polymorphs from a mixture of ethyl actate and methanol. Although the melting points of the materials differ by 7 K, the molecular conformations are almost identical and, in both polymorphs, each molecule is subject to four O-H...O hydrogen bonds.
Jones
Nigel A
NA
Department of Organic Chemistry, Chemistry Research Laboratory, University of Oxford, Mansfield Road, Oxford OX1 3TA, England. nigel.jones@chem.ox.ac.uk
Jenkinson
Sarah F
SF
Soengas
Raquel
R
Izumori
Ken
K
Fleet
George W J
GW
Watkin
David J
DJ
D003460:Crystallization; D018360:Crystallography, X-Ray; D003837:Deoxy Sugars / Q000737:chemistry*; D006601:Hexoses / Q000737:chemistry*; D006860:Hydrogen Bonding; D008958:Models, Molecular; D008968:Molecular Conformation
C518421:1-deoxytagatose; D003837:Deoxy Sugars; D006601:Hexoses