Multicomponent synthesis of 3-indolepropionic acids.
A three-component one-pot procedure (3-MC) was developed to assemble 3-indolepropionic acids from commercially available materials. This new methodology affords the title compounds in high yields and without the use of chromatography. [reaction: see text].
Adamo
Mauro F A
MF
Centre for Synthesis and Chemical Biology, Department of Pharmaceutical and Medicinal Chemistry, The Royal College of Surgeons in Ireland, 123 St. Stephen's Green, Dublin 2, Dublin, Ireland. madamo@rcsi.ie
Konda
Vivekananda R
VR
D007211:Indoles / Q000138:chemical synthesis* / Q000737:chemistry / Q000302:isolation & purification; D015394:Molecular Structure; D011422:Propionates / Q000138:chemical synthesis* / Q000737:chemistry / Q000302:isolation & purification; D013237:Stereoisomerism
D007211:Indoles; D011422:Propionates; C095446:3-(indol-3-yl)propionic acid