[A case of colon cancer liver metastases treated by combined therapies].
A 46-year-old male patient underwent sigmoidectomy with D2 lymph node dissection and partial resection of the bladder for advanced colon cancer in January 2000. The lesion was judged to be pT2, pN0, sP0, sH0, sM0 and Stage II, and the patient was treated on a regular schedule as an outpatient. Fourteen months after the first operation, liver metastases (S4, S5) were found and partial resections of the liver were performed. However, a recurrence had often been detected in the residual liver for five years afterwards. Liver resections had been repeated for four times before radiofrequency ablation was performed in January 2005. The patient received adjuvant chemotherapy with 5'-DFUR, 5-FU/l-LV (RPMI method), and TS-1. In January 2006, obstructive jaundice due to tumor growth occurred and a self-expandable metallic stent was placed in the narrowed portion of the intrahepatic bile duct. The patient is,currently undergoing FOLFOX4 and FOLFIRI regimens.
Ebisui
Chikara
C
Dept. of Surgery, Hyogo Prefectural Nishinomiya Hospital.
Fujiwara
Shinichi
S
Hayashi
Nobuyasu
N
Fukuchi
Nariaki
N
Tsujie
Masaki
M
Yoshida
Tetsuya
T
Sakita
Isao
I
Hasuike
Yasunori
Y
Fujimoto
Takayoshi
T
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D017115:Catheter Ablation; D017024:Chemotherapy, Adjuvant; D012809:Colon, Sigmoid / Q000601:surgery; D003131:Combined Modality Therapy; D005467:Floxuridine / Q000008:administration & dosage; D005472:Fluorouracil / Q000008:administration & dosage; D006498:Hepatectomy; D006801:Humans; D041781:Jaundice, Obstructive / Q000209:etiology / Q000628:therapy; D002955:Leucovorin / Q000008:administration & dosage; D008113:Liver Neoplasms / Q000556:secondary* / Q000628:therapy*; D008197:Lymph Node Excision; D008297:Male; D008875:Middle Aged; D012811:Sigmoid Neoplasms / Q000473:pathology* / Q000601:surgery; D015607:Stents; D005641:Tegafur / Q000008:administration & dosage
D005467:Floxuridine; D005641:Tegafur; D002955:Leucovorin; D005472:Fluorouracil; C025034:doxifluridine