[Lichen sclerosus in urological practice].
Lichen sclerosus in urological practice.


BACKGROUND
Lichen sclerosus is a sclerosing, inflammatory skin disease with unknown origin which causes secondary phimosis of the foreskin and stricture of the urethra. In the case of long term existence of it the prevalence of intraepithelial squamous cell neoplasia is increased.


OBJECTIVE
To identify the role of lichen sclerosus in adulthood phimosis and to categorize urological treatment. To define the proper therapy of lichen sclerosus, causing meatal and urethral stricture. To measure the incidence of lichen sclerosus in patients with squamous cell neoplasia.


METHODS
There was looked the incidence of lichen sclerosus in patient suffering with phimosis, recurrent urethral stricture, therapeutical options and presence of lichen sclerosus in patient with penile squamous cell neoplasia.


RESULTS
There were 123 foreskins sent for histological examination from 624 patients operated with circumcision in the last 5 years in the clinic. There were 76 (62%) times lichen sclerosus justified in 123 foreskins. There were lichen sclerosus found in 90% (9/10) of excised tissues of recurrent urethral strictures. There were lichen sclerosus noticed in 3 of 10 (33%) penile squamous cell carcinoma slides.


CONCLUSIONS
Lichen sclerosus can be detected in significant proportion of phimosis in adulthood. Lichen sclerosus can be found very often as the cause of recurrent urethral strictures, which takes necessary to perform 2 steps reconstructive operation with complete excision of the urethra and buccal graft emplacement. In the third of our all squamous cell carcinoma cases lichen sclerosus could be histologically shown, which give good reason for the opportunity of malignant disease development of this dermatological illness.
Nyirády
Peter
P
Semmelweis Egyetem, Altalános Orvostudományi Kar, Urológiai Klinika, Budapest. nyiradyp@hotmail.com
Borka
Katalin
K
Bánfi
Gergely
G
Kelemen
Zsolt
Z
D002294:Carcinoma, Squamous Cell / Q000175:diagnosis / Q000628:therapy; D002944:Circumcision, Male; D052816:Foreskin / Q000473:pathology*; D006801:Humans; D006814:Hungary / Q000453:epidemiology; D015994:Incidence; D018459:Lichen Sclerosus et Atrophicus / Q000150:complications / Q000175:diagnosis* / Q000453:epidemiology / Q000473:pathology / Q000601:surgery*; D008297:Male; D010409:Penile Diseases / Q000150:complications / Q000175:diagnosis* / Q000453:epidemiology / Q000473:pathology / Q000601:surgery*; D010412:Penile Neoplasms / Q000175:diagnosis / Q000628:therapy; D010688:Phimosis / Q000209:etiology; D014525:Urethral Stricture / Q000209:etiology