title: Enantioselective intramolecular aldol addition/dehydration reaction of a macrocyclic diketone: synthesis of the musk odorants (R)-muscone and (R,Z)-5-muscenone.
authors.affiliation: Firmenich SA, Corporate R&D Division, B.P. 239, 1211, Genève 8, Switzerland. oliver.knopff@firmenich.com
authors.forename: Oliver
authors.initials: O
authors.lastname: Knopff
authors.forename: Jérôme
authors.initials: J
authors.lastname: Kuhne
authors.forename: Charles
authors.initials: C
authors.lastname: Fehr
mesh_terms: D000447:Aldehydes / Q000737:chemistry*; D003516:Cycloparaffins / Q000138:chemical synthesis* / Q000737:chemistry; D007659:Ketones / Q000138:chemical synthesis / Q000737:chemistry*; D007700:Kinetics; D047028:Macrocyclic Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D008958:Models, Molecular; D015394:Molecular Structure; D013237:Stereoisomerism; D014867:Water / Q000737:chemistry*
chemical_list: C518850:(R,Z)-5-muscenone; D000447:Aldehydes; D003516:Cycloparaffins; D007659:Ketones; D047028:Macrocyclic Compounds; D014867:Water; C116609:3-hydroxybutanal; C031021:muscone