title: Investigation of a global collection of nontyphoidal Salmonella of various serotypes cultured between 1953 and 2004 for the presence of class 1 integrons.
abstract: In this study, antibiotic resistance profiles, and the presence of class 1 integrons were determined for 108 Salmonella isolates comprising 37 serotypes cultured from a variety of sources between 1953 and 2004. Antibiogram analyses showed that all isolates were resistant to streptomycin/spectinomycin. Molecular analysis revealed that 50% of the collection contained an integrase-encoding gene (int1) and 25% contained class 1 integrons. A Salmonella Wien isolate possessing a complete class 1 integron with a dfrA5-ereA2 gene arrangement within the variable region was characterized.
authors.affiliation: Veterinary Department, Cork County Council, County Hall, Cork, Ireland.
authors.forename: Brenda P
authors.initials: BP
authors.lastname: Murphy
authors.forename: Rebecca
authors.initials: R
authors.lastname: O'Mahony
authors.forename: James F
authors.initials: JF
authors.lastname: Buckley
authors.forename: Priscilla
authors.initials: P
authors.lastname: Shine
authors.forename: E Fidelma
authors.initials: EF
authors.lastname: Boyd
authors.forename: Deirdre
authors.initials: D
authors.lastname: Gilroy
authors.forename: Séamus
authors.initials: S
authors.lastname: Fanning
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology; D001483:Base Sequence; D004269:DNA, Bacterial / Q000235:genetics; D024901:Drug Resistance, Multiple, Bacterial; D032023:Integrons / Q000235:genetics*; D008826:Microbial Sensitivity Tests; D008957:Models, Genetic; D008969:Molecular Sequence Data; D012475:Salmonella / Q000145:classification / Q000187:drug effects / Q000235:genetics*; D012703:Serotyping; D013307:Streptomycin / Q000494:pharmacology*
chemical_list: D000900:Anti-Bacterial Agents; D004269:DNA, Bacterial; D013307:Streptomycin