Effects of intramuscular needle position on motor unit action potential metrics.
It is unclear whether there are clinically significant differences in amplitude, duration, and numbers of turns and phases if an electromyographic (EMG) study is performed near to, or far from, the end-plate zone. The effects of temporal dispersion of arriving muscle-fiber action potentials on quantitative motor unit action potential (MUAP) metrics were assessed in simulated and biologic muscles. Two muscle simulation models were studied with electrode recording positions near the motor end-plate zone and 50-75 mm away. When the electrode was moved away from the end-plate zone, averages of 20 MUAPs significantly decreased in amplitude and area, and increased in numbers of turns and phases, but there was no significant change in duration. In biologic muscles (both normal and pathologic), similar changes in average metrics were observed, but to lesser degrees; few were statistically significant. Zones of innervation in biologic muscles are broadly distributed and, during routine electrode studies, distances between random electrode placements and end-plate zones are therefore relatively short, leading to clinically insignificant changes in quantitative MUAP metrics with distance from the end-plate zone. Thus, electrode position within a muscle is unlikely to affect clinical MUAP interpretation.
Brownell
Alexander A
AA
Department of Biomedical Engineering, University of Utah, Salt Lake City, Utah, USA.
Bromberg
Mark B
MB
D000200:Action Potentials / Q000502:physiology*; D004568:Electrodiagnosis / Q000295:instrumentation / Q000379:methods*; D004576:Electromyography / Q000295:instrumentation / Q000379:methods; D006801:Humans; D008959:Models, Neurological; D009119:Muscle Contraction / Q000502:physiology*; D018482:Muscle, Skeletal / Q000502:physiology*; D009339:Needles; D009468:Neuromuscular Diseases / Q000175:diagnosis; D009469:Neuromuscular Junction / Q000502:physiology*; D011237:Predictive Value of Tests