title: Colonic squamous cell carcinoma in ulcerative colitis: Report of a case and review of the literature.
abstract: Squamous cell carcinoma (SCC) is a rare neoplasm in the colorectum. A case of SCC rising from an area of squamous metaplasia in the rectum is presented in a patient with long-standing ulcerative colitis and perianal warts. This is the first report in the literature describing the evolution of squamous metaplasia in the colonic mucosa into invasive carcinoma over time. Related literature on colorectal SCC and squamous metaplasia, and their relationships with inflammatory bowel disease and human papilloma virus, is reviewed.
authors.affiliation: Division of Gastroenterology, Hepatology and Nutrition, Department of Medicine, State University of New York at Buffalo, Buffalo, USA.
authors.forename: Huilan
authors.initials: H
authors.lastname: Cheng
authors.forename: Michael D
authors.initials: MD
authors.lastname: Sitrin
authors.forename: Sateesh K
authors.initials: SK
authors.lastname: Satchidanand
authors.forename: Jan M
authors.initials: JM
authors.lastname: Novak
mesh_terms: D002294:Carcinoma, Squamous Cell / Q000209:etiology* / Q000401:mortality / Q000601:surgery / Q000821:virology; D003093:Colitis, Ulcerative / Q000150:complications*; D003110:Colonic Neoplasms / Q000209:etiology* / Q000473:pathology / Q000821:virology; D015179:Colorectal Neoplasms / Q000401:mortality / Q000473:pathology / Q000601:surgery / Q000821:virology; D005260:Female; D006801:Humans; D008875:Middle Aged