title: [Liver abscess and infective endocarditis cases caused by Ruminococcus productus].
abstract: The genus Ruminococcus which are anaerobe Gram positive cocci, previously classified as Peptostreptococcus, may colonize the upper respiratory tract, gastrointestinal tract, vagina and skin of humans and animals. In this report a case of liver abscess and a case of infective endocarditis caused by Ruminoccocus productus, which is very rarely encountered in the clinical practice were presented. The first case was a 32 years old male who was admitted to the hospital in 2002, with the complaints of fever lasting for 20 days and pain while breathing. The abdominal ultrasonography revealed the presence of a liver abscess, and the drainage material from the abscess yielded Ruminococcus productus, identified in BACTEC 9200 (Becton Dickinson, Sparks, Md) anaerobe system. As the isolate was found to be sensitive to penicilin, the empirical gentamicin and ampicillin/sulbactam therapy was continued. The second case was a 25 years old male who was admitted to the hospital in 2005, with the signs of fever lasting for 3-4 months, chills, bone and joint pains. As multiple vegetations were detected in echocardiography, blood cultures were collected and empirical therapy with ceftriaxone and gentamicin was initiated with the preliminary diagnosis of infective endocarditis. Bacteria which were isolated from blood cultures by BACTEC 9200 system have been identified as R. productus. As this strain was also sensitive to penicillin, the empirical therapy was changed to penicilin and gentamicin. These two cases indicated that R. productus should be considered in complicated infections even if it is a rarely isolated species from the clinical samples.
authors.affiliation: Karadeniz Teknik Universitesi Tip Fakültesi, Infeksiyon Hastaliklan ve Klinik Mikrobiyoloji Anabilim Dali, Trabzon.
authors.forename: Nurgün
authors.initials: N
authors.lastname: Sucu
authors.forename: Iftihar
authors.initials: I
authors.lastname: Köksal
authors.forename: Gürdal
authors.initials: G
authors.lastname: Yilmaz
authors.forename: Kemalettin
authors.initials: K
authors.lastname: Aydin
authors.forename: Rahmet
authors.initials: R
authors.lastname: Caylan
authors.forename: Gönülden
authors.initials: G
authors.lastname: Aktoz Boz
mesh_terms: D000328:Adult; D000667:Ampicillin / Q000627:therapeutic use; D000900:Anti-Bacterial Agents / Q000494:pharmacology / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D004697:Endocarditis, Bacterial / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology; D005839:Gentamicins / Q000627:therapeutic use; D016908:Gram-Positive Bacterial Infections / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology; D006801:Humans; D008100:Liver Abscess / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology; D008297:Male; D010406:Penicillins / Q000494:pharmacology / Q000627:therapeutic use; D045857:Ruminococcus / Q000187:drug effects / Q000302:isolation & purification* / Q000472:pathogenicity; D013407:Sulbactam / Q000627:therapeutic use
chemical_list: D000900:Anti-Bacterial Agents; D005839:Gentamicins; D010406:Penicillins; C035444:sultamicillin; D000667:Ampicillin; D013407:Sulbactam