title: Celiprolol-induced lupus-like syndrome.
abstract: Systemic lupus erythematosus can be idiopathic or drug-induced. Although a number of beta-blockers have been reported to induce a lupus-like syndrome, to the best of our knowledge, no such case has been described following celiprolol therapy. We diagnosed a lupus-like syndrome in a 67-year-old female patient who developed febrile polyarthritis, percarditis, antinuclear and anti-histone antibodies after taking celiprolol for 2 years. Despite drug withdrawal, prolonged corticotherapy was needed to obtain clinical and biological remission.
authors.affiliation: Department of Cardiology, Avicenne Hospital, Bobigny, France. jean-christophe.charniot@avc.ap-hop-paris.fr
authors.forename: Jean-Christophe
authors.initials: JC
authors.lastname: Charniot
authors.forename: Thierry
authors.initials: T
authors.lastname: Genereau
authors.forename: Luc
authors.initials: L
authors.lastname: Mouthon
mesh_terms: D000368:Aged; D017272:Celiprolol / Q000009:adverse effects* / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000097:blood / Q000139:chemically induced* / Q000175:diagnosis
chemical_list: D017272:Celiprolol