Purtscher-like retinopathy as an initial presentation of a thrombotic microangiopathy associated with antineoplastic therapy.
We describe the case of a 31-year-old female with Hodgkin's lymphoma who developed renal and retinal thrombotic microangiopathy (TM) months after autologous bone marrow transplantation. Presenting symptoms were ocular and examination findings were consistent with a Purtscher-like retinopathy. This case demonstrates that patients being treated with antineoplastic therapy who develop TM should have an ocular examination for Purtscher retinopathy. The visual prognosis of Purtscher retinopathy is guarded.
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Service d'Ophtalmologie, Hôpital Foch, Suresnes, Paris, France. c.parc@hopital-foch.org
D000328:Adult; D000970:Antineoplastic Agents / Q000009:adverse effects*; D016026:Bone Marrow Transplantation / Q000009:adverse effects*; D005260:Female; D005500:Follow-Up Studies; D005938:Glucocorticoids / Q000627:therapeutic use; D006689:Hodgkin Disease / Q000150:complications / Q000175:diagnosis / Q000628:therapy*; D006801:Humans; D007674:Kidney Diseases / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D008775:Methylprednisolone / Q000627:therapeutic use*; D012008:Recurrence; D012164:Retinal Diseases / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D013927:Thrombosis / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D014182:Transplantation, Autologous; D016896:Treatment Outcome
D000970:Antineoplastic Agents; D005938:Glucocorticoids; D008775:Methylprednisolone