[Pleura's solitary fibrous tumor. Clinical pathology analysis of 17 cases].
BACKGROUND
Solitary fibrous tumor of the pleura (SFTP) is a rare neoplasm that usually originates from the visceral pleura, but it can occur in a wide range of tissues. Approximately 12% of pleural cases are malignant tumors and surgical excision usually become curative. The objective of this study is to present 17 new cases of SFTP and analyze the morphological characteristics that help to identify tumors with a malignant behavior.


METHODS
We did a retrospective review of the patients who had primary pleural tumors from January 1995 to August 2005.


RESULTS
Among a total of 94 primary pleural tumors, 17 patients were enrolled in this study, 8 men and 9 women, with a mean age of 63 years. Thirteen cases (76%) were benign and four cases (23%) were malignant. Local recurrences occurred in three cases. There were no metastases found. Recurrences occurred only in malignancy tumors. All malignant tumors were high cellularity and had hemiangiopericitic pattern, more than 4 mitoses per 10 high power fields, and moderate to marked polymorphism.


CONCLUSIONS
SFTP shows a benign biologic outcome in most of the cases. There are some histological characteristics that led to distinguish between benign and malign neoplasm.
Alvarado-Cabrero
Isabel
I
Servicio de Patología, Hospital de Oncología, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Mexico. isa98@prodigy.net.mx
Hernández
Susana
S
Kelly G
Javier
J
Cuenca-Buele
Sylvana
S
D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D018218:Neoplasms, Fibrous Tissue / Q000473:pathology*; D010997:Pleural Neoplasms / Q000473:pathology*