title: Human hydration level monitoring using embedded piezoresistive microcantilever sensors.
abstract: Embedded piezoresistive microcantilever (EPM) sensors were used to measure osmolality changes in both saliva mimic solutions and true human saliva. Osmolality changes in human saliva or urine may prove to be reliable, simple, and easy to measure markers for tracking human hydration levels. EPM sensors used in these experiments show good response to osmolality changes in both NaCl-based saliva mimic solutions and to human saliva. The addition of zero-point offset correction to EPM sensors allows for tracking of saliva osmolality changes with high accuracy. Also, the same EPM sensors exhibit a large enough range of osmolality response to make them potentially suitable for urine or blood serum osmolality monitoring.
authors.affiliation: Cantimer, Inc., Menlo Park, CA 94025, United States.
authors.forename: R
authors.initials: R
authors.lastname: Stewart
authors.forename: J
authors.initials: J
authors.lastname: Reed
authors.forename: J
authors.initials: J
authors.lastname: Zhong
authors.forename: K
authors.initials: K
authors.lastname: Morton
authors.forename: T L
authors.initials: TL
authors.lastname: Porter
mesh_terms: D015374:Biosensing Techniques; D003681:Dehydration; D017097:Electric Impedance; D004563:Electrochemistry / Q000379:methods; D004867:Equipment Design; D006801:Humans; D020100:Hydrogels; D007477:Ions; D009994:Osmolar Concentration; D012463:Saliva / Q000378:metabolism*; D012965:Sodium Chloride / Q000737:chemistry; D013696:Temperature; D014556:Urine / Q000737:chemistry; D014882:Water-Electrolyte Balance
chemical_list: D020100:Hydrogels; D007477:Ions; D012965:Sodium Chloride