[Reduction of prolonged QTc-interval related risks in treatment with neuropharmacological drugs. Recommendations for clinical practice].
A prolonged QTc-interval may cause potentially life-threatening arrhythmias. Almost all drugs used in psychiatric practice are able to prolong the QTc-interval. There are some indications that clinicians are not sufficiently aware of the risks of QTc-interval prolongation in clinical practice. By drawing up a list of risk factors associated with prolonged QTc-interval and by correcting for these factors as far as possible, one should be able to reduce the overall risk of potentially lethal arrhythmias and administer more appropriate pharmacological treatment.
van de Kraats
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GB
Meerkanten GGZ, Postbus 1000, 3850 BA, Ermelo. gbvdkraats@wanadoo.nl
Slob
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J
Tenback
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DE
D014150:Antipsychotic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D001145:Arrhythmias, Cardiac / Q000139:chemically induced* / Q000517:prevention & control; D005260:Female; D006801:Humans; D008133:Long QT Syndrome / Q000139:chemically induced* / Q000517:prevention & control*; D012307:Risk Factors; D012559:Schizophrenia / Q000188:drug therapy; D016171:Torsades de Pointes / Q000139:chemically induced / Q000517:prevention & control
D014150:Antipsychotic Agents