Acyl palladium species in synthesis: single-step synthesis of alpha,beta-unsaturated ketones from acid chlorides.
Conditions are reported for the facile, one-pot synthesis of alpha,beta-unsaturated ketones via the palladium-catalysed cross-coupling of acyl chlorides with hydrozirconated acetylenes, and its use in the 2-step synthesis of D-5-O-benzyl deoxyxylulose.
Cox
Russell J
RJ
School of Chemistry, University of Bristol, Cantock's Close, Bristol, BS8 1TS, UK. r.j.cox@bris.ac.uk
Evitt
Andrew S
AS