A population-based study of cancer incidence in solid organ transplants from donors at various risk of neoplasia.
A population-based cohort study of recipients of organs from donors with a recognized history or active cancer has been conducted by linking the Italian National Registry of Transplanted Patients and the National Registry of Donors with Neoplasia Risk. Between 2002 and 2004, 8,198 solid organ transplants have been performed in Italy, 108 of them with organs from 59 cadaveric donors with various risk of neoplasia. There were two reported cases of nonmelanoma skin cancer during the follow up of the transplanted patients, which lasted 27.6+/-11.3 months (234 patient-years). In our study, recipients of organs from donors with various degree of neoplasia risk are exposed to a low risk of cancer transmission.
Taioli
Emanuela
E
University of Pittsburgh Cancer Institute and the University of Pittsburgh Graduate School of Public Health, Pittsburgh, Pennsylvania, USA. taiolien@upmc.edu
Mattucci
Dino A
DA
Palmieri
Serena
S
Rizzato
Lucia
L
Caprio
Mario
M
Costa
Alessandro Nanni
AN
D002102:Cadaver; D015331:Cohort Studies; D003153:Community Health Services; D006801:Humans; D015994:Incidence; D007558:Italy / Q000453:epidemiology; D019520:Living Donors; D009369:Neoplasms / Q000453:epidemiology*; D016377:Organ Transplantation / Q000009:adverse effects*; D011183:Postoperative Complications / Q000453:epidemiology*; D012307:Risk Factors; D014019:Tissue Donors