[The effects of intracoronary infusion of bone marrow mononuclears on myocardial contractility].
The effects of intracoronary infusion of bone marrow mononuclears (BMM) on myocardial contractility after myocardial infarction (MI) was studied in 16 post-infarction patients. The intracoronary infusion of autologic BMM during the subacute period of MI did not have a significant effect on myocardial contractility, the functional class of chronic heart failure, physical tolerance, and quality of life evaluated three and six months after the transplantation. Intracoronary BMM transplantation did not provoke ventricular tachycardia or ventricular fibrillation. BMM transplantation into an infarcted myocardium did not exacerbate coronary heart disease in post-infarction patients.
Krylov
A L
AL
Riabov
V V
VV
Poponina
Iu S
IuS
Maslov
L N
LN
D001854:Bone Marrow Cells / Q000166:cytology*; D016026:Bone Marrow Transplantation / Q000379:methods*; D017023:Coronary Angiography; D003331:Coronary Vessels; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007261:Infusions, Intra-Arterial; D008297:Male; D008875:Middle Aged; D009000:Monocytes / Q000637:transplantation*; D009200:Myocardial Contraction / Q000502:physiology*; D009203:Myocardial Infarction / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000601:surgery*; D012189:Retrospective Studies; D016896:Treatment Outcome