title: Epithelioid osteosarcoma presenting as a rapidly expanding maxillary mass.
abstract: BACKGROUND
  Osteosarcomas of the jaws account for less than 10% of reported neoplasms of this type. Patients with osteosarcoma in this region tend to be in the late-third to mid-fourth decades of life. The osteoblastic, chondroblastic, and fibroblastic variants constitute the majority of lesions.
  
  
  METHODS
  A mass was observed in the maxilla of a 50-year-old male who presented for a complete odontectomy. Over the ensuing weeks, the mass substantially increased in size, despite multimodality treatment efforts.
  
  
  RESULTS
  Radiographic findings revealed a mixed density mass of the left maxilla. Histologic, immunohistochemical, and electron microscopy examination of the tumor showed a malignant mesenchymal neoplasm consisting of sheets of epithelioid and spindle cells exhibiting focal osteoid formation.
  
  
  CONCLUSIONS
  We report a rare and aggressive case of epithelioid osteosarcoma arising in the maxillofacial complex.
authors.affiliation: Department of Diagnostic Sciences, University of Medicine and Dentistry of New Jersey--New Jersey Dental School, Newark, New Jersey, USA. rinaggjo@umdnj.edu
authors.forename: Joseph
authors.initials: J
authors.lastname: Rinaggio
authors.forename: Greg F
authors.initials: GF
authors.lastname: Kewitt
authors.forename: H Stan
authors.initials: HS
authors.lastname: McGuff
mesh_terms: D015622:Epithelioid Cells / Q000473:pathology*; D017809:Fatal Outcome; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008441:Maxillary Neoplasms / Q000473:pathology*; D008854:Microscopy, Electron; D008875:Middle Aged; D012516:Osteosarcoma / Q000473:pathology*; D014057:Tomography, X-Ray Computed