title: Clinical delineation of fetal alcohol spectrum disorders (FASD) in Italian children: comparison and contrast with other racial/ethnic groups and implications for diagnosis and prevention.
abstract: In Italy, little is known about the spectrum of adverse fetal effects related to maternal alcohol use during pregnancy. In this paper, we report on the phenotype of Italian children with fetal alcohol spectrum disorders (FASD). These data were gathered as part of a field study assessing the prevalence of FASD in children in an in-school study in a rural area near Rome. The purposes of this paper are: (1) to completely characterize the clinical phenotype of a large cohort of Italian children with FASD; (2) to correlate and contrast the phenotype of this population with that observed in other populations and reported in the medical literature; (3) to discuss the drinking habits of Italian women, before, during and after pregnancy; and (4) to suggest mechanisms for intervention and prevention of FASD based on data gathered from this study.
authors.affiliation: University La Sapienza, Rome, Italy. m.ceccanti@uniromal.it
authors.forename: Mauro
authors.initials: M
authors.lastname: Ceccanti
authors.forename: Primavera
authors.initials: P
authors.lastname: Alessandra Spagnolo
authors.forename: Luigi
authors.initials: L
authors.lastname: Tarani
authors.forename: Maria
authors.initials: M
authors.lastname: Luisa Attilia
authors.forename: Luciana
authors.initials: L
authors.lastname: Chessa
authors.forename: Rosanna
authors.initials: R
authors.lastname: Mancinelli
authors.forename: Michele
authors.initials: M
authors.lastname: Stegagno
authors.forename: Guido
authors.initials: G
authors.lastname: Francesco Sasso
authors.forename: Marina
authors.initials: M
authors.lastname: Romeo
authors.forename: Kenneth L
authors.initials: KL
authors.lastname: Jones
authors.forename: Luther K
authors.initials: LK
authors.lastname: Robinson
authors.forename: Miguel
authors.initials: M
authors.lastname: Del Campo
authors.forename: J
authors.initials: J
authors.lastname: Phillip Gossage
authors.forename: Philip A
authors.initials: PA
authors.lastname: May
authors.forename: H
authors.initials: H
authors.lastname: Eugene Hoyme
mesh_terms: D000438:Alcohols; D002648:Child; D002658:Developmental Disabilities / Q000209:etiology / Q000473:pathology / Q000503:physiopathology; D005006:Ethnicity; D005260:Female; D063647:Fetal Alcohol Spectrum Disorders / Q000175:diagnosis / Q000453:epidemiology / Q000503:physiopathology; D005387:Finland / Q000453:epidemiology / Q000208:ethnology; D006801:Humans; D007558:Italy / Q000453:epidemiology / Q000208:ethnology; D008297:Male; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects / Q000175:diagnosis / Q000453:epidemiology / Q000503:physiopathology; D013019:South Africa / Q000453:epidemiology / Q000208:ethnology
chemical_list: D000438:Alcohols