The contribution of Gianni Bonadonna to the history of chemotherapy.
The history of cancer chemotherapy and of the discipline of medical oncology has been that of drug discovery. The pioneering discoveries of the early days of chemotherapy have allowed the development of a paradigm for drug discovery that persists, with modifications to the present day. This review article summarizes the seminal work of the Italian scientist Gianni Bonadonna on the treatment of breast cancer and Hodgkin's disease.
Ribatti
Domenico
D
Department of Human Anatomy and Histology, University of Bari Medical School, Piazza G. Cesare, 11, Policlinico, 70124 Bari, Italy. ribatti@anatomia.uniba.it
D000970:Antineoplastic Agents / Q000266:history / Q000627:therapeutic use*; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage / Q000627:therapeutic use; D001761:Bleomycin / Q000008:administration & dosage; D001943:Breast Neoplasms / Q000188:drug therapy / Q000266:history; D002945:Cisplatin / Q000008:administration & dosage; D003606:Dacarbazine / Q000008:administration & dosage; D004317:Doxorubicin / Q000008:administration & dosage; D005260:Female; D005472:Fluorouracil / Q000008:administration & dosage; D049673:History, 20th Century; D006689:Hodgkin Disease / Q000188:drug therapy / Q000266:history; D006801:Humans; D007558:Italy; D008727:Methotrexate / Q000008:administration & dosage; D009369:Neoplasms / Q000188:drug therapy* / Q000266:history; D014747:Vinblastine / Q000008:administration & dosage
D000970:Antineoplastic Agents; D001761:Bleomycin; D014747:Vinblastine; D003606:Dacarbazine; D004317:Doxorubicin; D002945:Cisplatin; D005472:Fluorouracil; D008727:Methotrexate