Isolation of quinolone-resistant Escherichia coli found in major rivers in Korea.
Twenty isolates resistant to seven quinolones were isolated from major rivers in Korea. All isolates had three mutations, Ser83-->Leu and Asp87-->Asn in GyrA and Ser80-->Ile or Ser80-->Arg in ParC and three isolates had an additional mutation Glu84-->Gly or Glu84-->Val in ParC. In addition, a clonal spread was not found in these isolates.
Jung
Dahye
D
Culture Collection of Antimicrobial Resistant Microbes, Department of Biology, Seoul Women's University, Republic of Korea.
Lee
Min Young
MY
Kim
Jung Min
JM
Lee
Je Chul
JC
Cho
Dong Taek
DT
Lee
Yeonhee
Y
D000818:Animals; D000890:Anti-Infective Agents / Q000494:pharmacology*; D027101:DNA Topoisomerase IV / Q000235:genetics; D024881:Drug Resistance, Bacterial; D004926:Escherichia coli / Q000187:drug effects* / Q000235:genetics / Q000302:isolation & purification*; D006801:Humans; D007723:Korea; D008826:Microbial Sensitivity Tests; D009154:Mutation; D015363:Quinolones / Q000494:pharmacology*; D045483:Rivers / Q000382:microbiology*
D000890:Anti-Infective Agents; D015363:Quinolones; D027101:DNA Topoisomerase IV