title: [A case of colon cancer liver metastases treated by combined therapies].
abstract: A 46-year-old male patient underwent sigmoidectomy with D2 lymph node dissection and partial resection of the bladder for advanced colon cancer in January 2000. The lesion was judged to be pT2, pN0, sP0, sH0, sM0 and Stage II, and the patient was treated on a regular schedule as an outpatient. Fourteen months after the first operation, liver metastases (S4, S5) were found and partial resections of the liver were performed. However, a recurrence had often been detected in the residual liver for five years afterwards. Liver resections had been repeated for four times before radiofrequency ablation was performed in January 2005. The patient received adjuvant chemotherapy with 5'-DFUR, 5-FU/l-LV (RPMI method), and TS-1. In January 2006, obstructive jaundice due to tumor growth occurred and a self-expandable metallic stent was placed in the narrowed portion of the intrahepatic bile duct. The patient is,currently undergoing FOLFOX4 and FOLFIRI regimens.
authors.affiliation: Dept. of Surgery, Hyogo Prefectural Nishinomiya Hospital.
authors.forename: Chikara
authors.initials: C
authors.lastname: Ebisui
authors.forename: Shinichi
authors.initials: S
authors.lastname: Fujiwara
authors.forename: Nobuyasu
authors.initials: N
authors.lastname: Hayashi
authors.forename: Nariaki
authors.initials: N
authors.lastname: Fukuchi
authors.forename: Masaki
authors.initials: M
authors.lastname: Tsujie
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Yoshida
authors.forename: Isao
authors.initials: I
authors.lastname: Sakita
authors.forename: Yasunori
authors.initials: Y
authors.lastname: Hasuike
authors.forename: Takayoshi
authors.initials: T
authors.lastname: Fujimoto
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D017115:Catheter Ablation; D017024:Chemotherapy, Adjuvant; D012809:Colon, Sigmoid / Q000601:surgery; D003131:Combined Modality Therapy; D005467:Floxuridine / Q000008:administration & dosage; D005472:Fluorouracil / Q000008:administration & dosage; D006498:Hepatectomy; D006801:Humans; D041781:Jaundice, Obstructive / Q000209:etiology / Q000628:therapy; D002955:Leucovorin / Q000008:administration & dosage; D008113:Liver Neoplasms / Q000556:secondary* / Q000628:therapy*; D008197:Lymph Node Excision; D008297:Male; D008875:Middle Aged; D012811:Sigmoid Neoplasms / Q000473:pathology* / Q000601:surgery; D015607:Stents; D005641:Tegafur / Q000008:administration & dosage
chemical_list: D005467:Floxuridine; D005641:Tegafur; D002955:Leucovorin; D005472:Fluorouracil; C025034:doxifluridine