title: Treatment and prevention of depression after surgery for hip fracture in older people: randomized, controlled trials.
abstract: OBJECTIVE
  To evaluate the effect of a psychiatric intervention in treating depression (treatment study) and the effect of a psychological treatment in preventing depression (prevention study) after hip fracture in older people.
  
  
  METHODS
  Two linked randomized, controlled trials.
  
  
  METHODS
  Orthopedic units in Manchester, England.
  
  
  METHODS
  Two hundred ninety-three older people who had undergone surgery for a fractured hip: 121 in the treatment study and 172 in the prevention study.
  
  
  METHODS
  The Geriatric Depression Scale and Hospital Anxiety and Depression Scale for mood, functional tests for mobility and pain measures.
  
  
  RESULTS
  There was a slight reduction in depressive symptoms in the active arm of the treatment study. In the prevention study, there was no significant difference in incident depression between the psychological intervention and treatment as usual. There were no differences in the functional and pain outcomes.
  
  
  CONCLUSIONS
  The results from these two randomized, controlled trials show that, after hip fracture surgery, no statistically significant benefits can be achieved from a psychiatric intervention in people who are depressed or a psychological intervention to prevent the onset of depression.
authors.affiliation: Division of Psychiatry, University of Manchester, Manchester, UK. alistair.burns@manchester.ac.uk
authors.forename: Alistair
authors.initials: A
authors.lastname: Burns
authors.forename: Sube
authors.initials: S
authors.lastname: Banerjee
authors.forename: Julie
authors.initials: J
authors.lastname: Morris
authors.forename: Yvonne
authors.initials: Y
authors.lastname: Woodward
authors.forename: Robert
authors.initials: R
authors.lastname: Baldwin
authors.forename: Rebekah
authors.initials: R
authors.lastname: Proctor
authors.forename: Nicholas
authors.initials: N
authors.lastname: Tarrier
authors.forename: Neil
authors.initials: N
authors.lastname: Pendleton
authors.forename: Deborah
authors.initials: D
authors.lastname: Sutherland
authors.forename: Glynne
authors.initials: G
authors.lastname: Andrew
authors.forename: Mike
authors.initials: M
authors.lastname: Horan
mesh_terms: D000369:Aged, 80 and over; D000928:Antidepressive Agents / Q000627:therapeutic use; D015928:Cognitive Behavioral Therapy; D003863:Depression / Q000175:diagnosis / Q000209:etiology / Q000517:prevention & control* / Q000628:therapy*; D005260:Female; D006620:Hip Fractures / Q000523:psychology* / Q000601:surgery; D006801:Humans; D016015:Logistic Models; D008297:Male; D011183:Postoperative Complications / Q000523:psychology; D016896:Treatment Outcome
chemical_list: D000928:Antidepressive Agents