title: Excessive alcohol consumption is associated with reduced quality of life among methadone patients.
abstract: OBJECTIVE
  To evaluate the impact of excessive alcohol consumption on the health-related quality of life of patients receiving methadone treatment for opioid dependence.
  
  
  METHODS
  A cross-sectional survey.
  
  
  METHODS
  One hundred and ninety-two patients attending out-patient methadone clinics in the south-east of England, United Kingdom.
  
  
  METHODS
  Quality of life (QoL) was assessed using the Medical Outcomes Study: General Health Survey, Short Form (SF-12). Alcohol consumption was assessed using the Alcohol Use Disorders Identification Test (AUDIT).
  
  
  RESULTS
  Approximately one-third of the sample (57/192) were AUDIT-positive (score > or = 8) and 20 of the 135 AUDIT-negative patients reported past history of alcohol problems. AUDIT-positive patients were less satisfied with their methadone dose than AUDIT-negative patients (P = 0.002), despite having a higher dose. AUDIT-positive patients reported more physical (P = 0.020) and psychological (P = 0.034) health problems and poorer QoL (P = 0.008) with an estimated effect size of 0.46. Lower QoL scores for AUDIT-positive patients affected both 'physical' (P = 0.009) and 'psychological' (P = 0.012) health domains with poor role functioning ('role limitation' due to physical health, P < 0.001 and to emotional health, P = 0.009), social functioning (P = 0.015) and self-perceived general health (P = 0.029).
  
  
  CONCLUSIONS
  Excessive alcohol consumption may be associated with a distinctive pattern of QoL impairment in methadone patients. In addition to advising methadone patients regarding their alcohol consumption, comprehensive care plans should seek to restore normal personal, family and social role functioning through the provision of appropriate health and social care.
authors.affiliation: East Kent Community Drug Service, KCA, Ashford, Kent, UK. rsenbanjo@kca.org.uk
authors.forename: Richard
authors.initials: R
authors.lastname: Senbanjo
authors.forename: Kim
authors.initials: K
authors.lastname: Wolff
authors.forename: Jane
authors.initials: J
authors.lastname: Marshall
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000428:Alcohol Drinking / Q000009:adverse effects* / Q000523:psychology; D003430:Cross-Sectional Studies; D004739:England / Q000453:epidemiology; D006304:Health Status; D006801:Humans; D008297:Male; D008691:Methadone / Q000627:therapeutic use*; D008875:Middle Aged; D009294:Narcotics / Q000627:therapeutic use*; D009293:Opioid-Related Disorders / Q000534:rehabilitation*; D011788:Quality of Life / Q000523:psychology*
chemical_list: D009294:Narcotics; D008691:Methadone