title: Tri- and hexavalent mannoside clusters as potential inhibitors of type 1 fimbriated bacteria using pentaerythritol and triazole linkages.
abstract: Several oligomannoside clusters having a hundred-fold increase in affinities toward E. coli were synthesized by Cu(I)-catalyzed [1,3]-dipolar cycloadditions using pentaerythritol scaffolds bearing either alkyne or azide functionalities.
authors.affiliation: Department of Chemistry, Université du Québec à Montréal, PO Box 8888, Succ. Centre-Ville Montreal, Québec, Canada H3C 3P8.
authors.forename: Mohamed
authors.initials: M
authors.lastname: Touaibia
authors.forename: Tze Chieh
authors.initials: TC
authors.lastname: Shiao
authors.forename: Alex
authors.initials: A
authors.lastname: Papadopoulos
authors.forename: Jonathan
authors.initials: J
authors.lastname: Vaucher
authors.forename: Qingan
authors.initials: Q
authors.lastname: Wang
authors.forename: Karima
authors.initials: K
authors.lastname: Benhamioud
authors.forename: René
authors.initials: R
authors.lastname: Roy
mesh_terms: D004926:Escherichia coli / Q000737:chemistry* / Q000378:metabolism*; D008362:Mannosides / Q000096:biosynthesis* / Q000737:chemistry*; D015394:Molecular Structure; D011409:Propylene Glycols / Q000737:chemistry*; D014230:Triazoles / Q000737:chemistry*
chemical_list: D008362:Mannosides; D011409:Propylene Glycols; D014230:Triazoles; C008783:pentaerythritol