title: Seven-membered cyclic sulfite eudesmane derivatives: partial synthesis, structural determination, and enzymatic resolution.
abstract: Two chromatographically inseparable, diastereomeric eudesmane cyclic sulfites have been semisynthesized from alpha-santonin. This diastereomeric mixture was resolved by enzymatic acetylation with CCL. Each cyclic sulfite derivative was individually characterized on the basis of its spectroscopic and crystallographic properties.
authors.affiliation: Departamento de Química Orgánica, Facultad de Ciencias, Universidad de Granada, E-18071 Granada, Spain.
authors.forename: Andrés
authors.initials: A
authors.lastname: García-Granados
authors.forename: Andrés
authors.initials: A
authors.lastname: Parra
authors.forename: Francisco
authors.initials: F
authors.lastname: Rivas
authors.forename: Alejandro J
authors.initials: AJ
authors.lastname: Segovia
mesh_terms: D002175:Candida / Q000201:enzymology; D018360:Crystallography, X-Ray; D003500:Cyclization; D008049:Lipase / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy / Q000379:methods / Q000592:standards; D008958:Models, Molecular; D012015:Reference Standards; D012680:Sensitivity and Specificity; D045787:Sesquiterpenes, Eudesmane / Q000138:chemical synthesis / Q000737:chemistry; D013237:Stereoisomerism; D013447:Sulfites / Q000138:chemical synthesis / Q000737:chemistry
chemical_list: D045787:Sesquiterpenes, Eudesmane; D013447:Sulfites; C015872:eudesmane; D008049:Lipase