title: [A human T-cell lymphotropic virus type 1 carrier presenting with Sjögren's syndrome and bronchopneumopathy].
abstract: A 77-year-old asymptomatic woman was found to have a coin lesion on a chest radiograph. Chest computed tomography scans showed the coin lesion, bronchiectasis, tree-in-bud appearance, and ground glass opacity. The histopathology of the lung by video-assisted thoracic surgery showed organizing pneumonia, follicular bronchiolitis, and non-specific interstitial pneumonitis patterns, all of which consisted of mainly mature lymphocytes and plasma cells. She suffered from dry eyes and had a high level of serum anti-SS-A antibody. Examination of her eyes and mouth revealed Sjögren's syndrome. The patient herself and her parents were born in Nagasaki prefecture, an area where human T-cell lymphotropic virus type 1 (HTLV-1) is endemic, and her sister suffered from a hematological malignancy. She was found to be an HTLV-1 carrier. We finally made a diagnosis of an HTLV-1 carrier presenting with Sjögren's syndrome and bronchopneumopathy. This combination (HTLV-1, Sjögren's syndrome, and bronchopneumopathy) is rarely reported.
authors.affiliation: Department of Internal Medicine, Izumi City Hospital.
authors.forename: Masato
authors.initials: M
authors.lastname: Uji
authors.forename: Haruhiko
authors.initials: H
authors.lastname: Matsushita
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Watanabe
authors.forename: Tomohiro
authors.initials: T
authors.lastname: Suzumura
mesh_terms: D000368:Aged; D002353:Carrier State / Q000473:pathology; D018549:Cryptogenic Organizing Pneumonia / Q000209:etiology* / Q000473:pathology; D005260:Female; D015490:HTLV-I Infections / Q000150:complications*; D015368:Human T-lymphotropic virus 1; D006801:Humans; D012859:Sjogren's Syndrome / Q000209:etiology*