title: Altered left ventricular diastolic filling following a marathon is a reproducible phenomenon.
abstract: The present study examined the reproducibility of alterations in left ventricular function and cardiac biomarkers in a cohort of athletes following two marathons, one year apart. Eight participants in the 2004 and 2005 London Marathons were tested pre- and post-race via echocardiography and humoral analysis. Reductions in diastolic filling, unrelated to loading or heart rate, following both marathons were reproducible within individuals, which may be a function of exercise duration. In contrast, exercise-induced cardiac troponin release was inconsistent.
authors.forename: Natalie
authors.initials: N
authors.lastname: Middleton
authors.forename: Rob
authors.initials: R
authors.lastname: Shave
authors.forename: Keith
authors.initials: K
authors.lastname: George
authors.forename: Gregory
authors.initials: G
authors.lastname: Whyte
authors.forename: Emma
authors.initials: E
authors.lastname: Hart
authors.forename: David
authors.initials: D
authors.lastname: Oxborough
authors.forename: Jan
authors.initials: J
authors.lastname: Forster
authors.forename: David
authors.initials: D
authors.lastname: Gaze
mesh_terms: D000328:Adult; D015331:Cohort Studies; D006801:Humans; D015203:Reproducibility of Results; D012420:Running / Q000502:physiology*; D013318:Stroke Volume / Q000502:physiology*; D016277:Ventricular Function, Left / Q000502:physiology*