Base-assisted regio- and diastereoselective conversion of functionalized furans to butenolides using singlet oxygen.
A facile synthesis of beta-functionalized gamma-hydroxybutenolides was achieved using a Baylis-Hillman reaction followed by singlet oxygen oxidation. The conversion from 3-furfural was regio- and diastereoselective. [reaction: see text].
Patil
Santoshkumar N
SN
Department of Chemistry & Biomolecular Sciences, Macquarie University, Sydney, NSW 2109, Australia.
Liu
Fei
F
D015107:4-Butyrolactone / Q000031:analogs & derivatives / Q000138:chemical synthesis* / Q000737:chemistry; D005663:Furans / Q000737:chemistry*; D015394:Molecular Structure; D010100:Oxygen / Q000737:chemistry*; D013237:Stereoisomerism
D005663:Furans; D015107:4-Butyrolactone; D010100:Oxygen