title: [Construction of a therapeutic effect evaluation system for patients with primary liver cancer based on syndrome differentiation in traditional Chinese medicine].
abstract: OBJECTIVE
  To construct a system of therapeutic effect evaluation for patients with primary liver cancer according to the theory of syndrome differentiation in traditional Chinese medicine (TCM), and to examine its reliability.
  
  
  METHODS
  Analytic hierarchy process and 100 mm surveyor's rod method were applied to obtain bottom layer and top level syndromes, which were used to construct the method of therapeutic effect evaluation, and its reliability was verified in clinical practice by comparing with some evaluation criteria in Western medicine, such as cancer severity scale; Karnofsky performance scale; Child-Pugh classification, cancer staging classification, and quality of life scale, etc.
  
  
  RESULTS
  A system of therapeutic effect evaluation was constructed, and it could reflect the progress of tumor, changes of hepatic function and constitution. The evaluation scores acquired from the system were highly associated with the quality of life of the patients.
  
  
  CONCLUSIONS
  The system of therapeutic effect evaluation can reflect the severity of disease and the characteristics of TCM treatment.
authors.affiliation: Department of Traditional Chinese Medicine, Changhai Hospital, Second Military Medical University, Shanghai 200433, China.
authors.forename: Dong-tao
authors.initials: DT
authors.lastname: Li
authors.forename: Chang-quan
authors.initials: CQ
authors.lastname: Ling
authors.forename: Qing-bo
authors.initials: QB
authors.lastname: Lang
authors.forename: De-zeng
authors.initials: DZ
authors.lastname: Zhu
authors.forename: Chao-qin
authors.initials: CQ
authors.lastname: Yu
authors.forename: Zhe
authors.initials: Z
authors.lastname: Chen
authors.forename: Xiao-feng
authors.initials: XF
authors.lastname: Zhai
authors.forename: Jie
authors.initials: J
authors.lastname: Shen
authors.forename: Jin-feng
authors.initials: JF
authors.lastname: Zhang
authors.forename: Bai-hong
authors.initials: BH
authors.lastname: Zhang
mesh_terms: D006528:Carcinoma, Hepatocellular / Q000188:drug therapy / Q000473:pathology; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use; D006801:Humans; D017567:Karnofsky Performance Status; D008113:Liver Neoplasms / Q000188:drug therapy* / Q000473:pathology; D008516:Medicine, Chinese Traditional; D017063:Outcome Assessment, Health Care / Q000379:methods* / Q000592:standards; D008517:Phytotherapy
chemical_list: D004365:Drugs, Chinese Herbal