title: Fulminant sepsis after second-trimester amniocentesis in pregnant women by in vitro fertilization and embryo transfer.
abstract: Second-trimester amniocentesis is a common procedure for prenatal diagnosis. Sepsis is a rare complication after amniocentesis and may rapidly deteriorate if prompt treatment, including broad-spectrum antibiotics and removal of the infected abortus, is delayed. In vitro fertilization and embryo transfer (IVF-ET) is a standard final treatment for infertile women. Transvaginal oocyte retrieval is necessary for such women; this procedure potentially causes Escherichia coli attaching and effacing in the abdominal cavity. Here we report that two pregnant women by IVF-ET developed sepsis after second-trimester amniocentesis. The cause of sepsis after amniocentesis is still unknown. We provided the possibility of the causation of the E. coli infection associated with the previous intra-abdominal procedure, but it needs more evidence to prove it.
authors.affiliation: Department of Obstetrics and Gynecology, Changhua Christian Hospital, Changhua, Taiwan (ROC). 58436@cch.org.tw
authors.forename: Hsin-Hung
authors.initials: HH
authors.lastname: Wu
authors.forename: Guang-Perng
authors.initials: GP
authors.lastname: Yeh
authors.forename: Tsung-Che
authors.initials: TC
authors.lastname: Hsieh
authors.forename: Kuo-Cherng
authors.initials: KC
authors.lastname: Lin
mesh_terms: D000328:Adult; D000649:Amniocentesis / Q000009:adverse effects*; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D003131:Combined Modality Therapy; D004107:Dilatation and Curettage; D004624:Embryo Transfer / Q000009:adverse effects; D004927:Escherichia coli Infections / Q000188:drug therapy / Q000209:etiology / Q000601:surgery; D005260:Female; D005307:Fertilization in Vitro / Q000009:adverse effects; D006801:Humans; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000188:drug therapy / Q000209:etiology* / Q000601:surgery; D011262:Pregnancy Trimester, Second; D018805:Sepsis / Q000188:drug therapy / Q000209:etiology* / Q000601:surgery
chemical_list: D000900:Anti-Bacterial Agents