title: Transient hypoxia and downregulation of circulating prohepcidin concentrations in healthy young men.
abstract: To determine the impact of acute hypoxia on prohepcidin concentrations in humans, we measured concentrations of this peptide in serum collected during and after a transient period (30 min) of hypoxia and during normoxia. Prohepcidin concentrations were significantly lower 150 min after the end of hypoxia than after normoxia (p=0.028).
authors.forename: Christian
authors.initials: C
authors.lastname: Benedict
authors.forename: Andrew J
authors.initials: AJ
authors.lastname: Ghio
authors.forename: Hartmut
authors.initials: H
authors.lastname: Gehring
authors.forename: Bernd
authors.initials: B
authors.lastname: Schultes
authors.forename: Achim
authors.initials: A
authors.lastname: Peters
authors.forename: Kerstin M
authors.initials: KM
authors.lastname: Oltmanns
mesh_terms: D000328:Adult; D023181:Antimicrobial Cationic Peptides / Q000097:blood*; D015536:Down-Regulation; D064451:Hepcidins; D006706:Homeostasis; D006801:Humans; D000860:Hypoxia; D007501:Iron / Q000097:blood; D010100:Oxygen / Q000378:metabolism; D010455:Peptides / Q000737:chemistry; D011498:Protein Precursors / Q000097:blood*; D013997:Time Factors
chemical_list: D023181:Antimicrobial Cationic Peptides; D064451:Hepcidins; D010455:Peptides; D011498:Protein Precursors; D007501:Iron; D010100:Oxygen