Targeting an old mechanism in a new disease-protection of glutamatergic dysfunction in depression.
Sattler
Rita
R
Department of Neurology, Johns Hopkins University, Baltimore, MD 21287, USA. rsattle1@jhmi.edu
Rothstein
Jeffrey D
JD
D027322:Amino Acid Transport System X-AG / Q000502:physiology*; D000818:Animals; D000928:Antidepressive Agents / Q000627:therapeutic use*; D001921:Brain / Q000187:drug effects / Q000503:physiopathology; D002443:Ceftriaxone / Q000627:therapeutic use; D003866:Depressive Disorder / Q000188:drug therapy* / Q000503:physiopathology*; D018698:Glutamic Acid / Q000378:metabolism*; D006801:Humans; D051379:Mice; D018696:Neuroprotective Agents / Q000627:therapeutic use*; D017470:Receptors, Glutamate / Q000187:drug effects* / Q000502:physiology*; D016896:Treatment Outcome
D027322:Amino Acid Transport System X-AG; D000928:Antidepressive Agents; D018696:Neuroprotective Agents; D017470:Receptors, Glutamate; D018698:Glutamic Acid; D002443:Ceftriaxone