title: [History and definition(s) of metabolic syndrome].
abstract: Metabolic syndrome--a cluster of metabolic diseases and hypertension--is not a new disease. It has been present in the upper classes of all highly developed cultures suffering from over-nutrition and limited physical activity. In the medical literature, it can be found in Renaissance and Baroque times. We are presently experiencing a global tsunami of this syndrome as over-nutrition and lack of movement are typical for large groups of the population. The current definition of metabolic syndrome of the American Heart Association/National Heart, Lung and Blood Institute and the International Diabetes Federation incorporates the quartet central obesity, hypertension, increased blood sugar and dyslipidemia (hypertriglyceridemia, low HDL cholesterol). Thus, simple, collective diagnostics and therapy for this finely meshed group of diseases together with its risk factors is possible.
authors.affiliation: Zentrum für Klinische Studien, Forschungsbereich Endokrinologie und Stoffwechsel, GWT-TUD GmbH, 01307 , Fiedlerstrasse 34, Dresden, Deutschland. Hanefeld@gwtonline-zks.de
authors.forename: M
authors.initials: M
authors.lastname: Hanefeld
authors.forename: F
authors.initials: F
authors.lastname: Schaper
authors.forename: A
authors.initials: A
authors.lastname: Ceriello
mesh_terms: D002318:Cardiovascular Diseases / Q000266:history*; D003924:Diabetes Mellitus, Type 2 / Q000266:history*; D050171:Dyslipidemias / Q000266:history*; D049668:History, 15th Century; D049669:History, 16th Century; D049670:History, 17th Century; D049671:History, 18th Century; D049672:History, 19th Century; D049673:History, 20th Century; D049674:History, 21st Century; D049691:History, Medieval; D006801:Humans; D006973:Hypertension / Q000266:history*; D024821:Metabolic Syndrome / Q000266:history*