Enhanced wound contraction and epithelization period in steroid treated rats: role of pyramid environment.
Contribution and role of a pyramid/square box on the wound healing suppressant effect of dexamethasone was studied in rats of either sex using excision wound model to record the wound contraction rate and epithelization period. The results showed enhanced wound contraction rate and decreased epithelization period in the pyramid-exposed rats as compared to controls. Thus, it appears that pyramid environment facilitates the process of wound healing. Also, the wound healing suppressant effects of dexamethasone were significantly reduced.
Kamath
Surekha
S
Department of Physiology, Melaka Manipal Medical College, Manipal 576104, India. surekharkamath@yahoo.com
Rao
S Gurumadhva
SG
Murthy
K Dilip
KD
Bairy
K L
KL
Bhat
Surekha
S
D000818:Animals; D003907:Dexamethasone / Q000009:adverse effects; D004777:Environment; D005260:Female; D008297:Male; D008954:Models, Biological; D051381:Rats; D017208:Rats, Wistar; D013256:Steroids / Q000009:adverse effects*; D014945:Wound Healing / Q000187:drug effects*
D013256:Steroids; D003907:Dexamethasone