New Eremophilane Type Lactones from the Roots of Ligularia veitchiana.
Phytochemical investigation of the roots of LIGULARIA VEITCHIANA has resulted in the characterization of two new eremophilanolides together with beta-sitosterol, stigmasterol, taraxol, and liguhodgsonal whose structure was further confirmed by the (13)C-NMR techniques. The structures of the new constituents were elucidated by spectroscopic methods and shown to be 1beta, 10beta-epoxy-6beta(2'-hydroxymethylacryloyloxy)-8beta-hydroxy-eremophila-7(11)-en-12,8alpha-olide ( 1) and 1beta, 10beta-epoxy-6beta-(2'-hydroxymethylacryloyloxy)-8beta-ethoxy-eremophila-7(11)-en-12,8alpha-olide ( 2).
Jia
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State Key Laboratory of Applied Organic Chemistry at Lanzhou University. Lanzhou 730000, People's Republic of China.
Zhao
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Tan
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