Short term change of urinary N-acetyl-beta-D-glucosaminidase in reduced kidney mass with renal artery ligation.
The aim of the present study was to evaluate short term urinary NAG levels in a model of reduced kidney mass. The half and quarter kidney mass were made from ligation of the renal artery. Both groups decreased in the level of excreted NAG on day 1 and 2 after operation. On day 5 after operation, both groups achieved urinary enzyme levels comparable to that of the sham-operated group. The remaining compensated nephrons held normal range of excreted urinary NAG levels, although reduced number of nephrons resulted in a decline in urinary NAG levels.
Ebisawa
Takashi
T
Department of Veterinary Medicine, College of Bioresouce Sciences, Nihon University, Fujisawa, Kanagawa, Japan.
Uechi
Masami
M
Hori
Yasutomo
Y
Yamano
Shigeki
S
D000118:Acetylglucosaminidase / Q000652:urine*; D000818:Animals; D007668:Kidney / Q000033:anatomy & histology*; D008297:Male; D009929:Organ Size; D051381:Rats; D017207:Rats, Sprague-Dawley; D012077:Renal Artery / Q000601:surgery*; D013997:Time Factors
D000118:Acetylglucosaminidase