[A case of effective chemoradiation therapy against anal fistula carcinoma recurred 10 years after surgery].
A male in his eighties underwent abdominoperineal resection under the diagnosis of adenocarcinoma associated with anal fistula (P0, H0, n (-), A1, stage II, ly0, v0). Ten years after the surgery, a painful lymph node swelling was noticed in the left inguinal region. Biopsy specimen showed adenocarcinoma consisting of severe dysplastic cells. Radiotherapy was performed in the pelvic region at a total dose of 50 Gy (2 Gy/day). After the radiotherapy, left inguinal and pelvic lymph nodes markedly shrank and became painless. After one month, the chemotherapy with UFT (UFT 300 mg/day) was started. One year thereafter, para-aortic lymph nodes were found to be enlarged, but a good quality of life was obtained without elevation of tumor markers.
Nakagawa
Sumiko
S
Dept, of Surgery, Nishinomiya Municipal Central Hospital.
Amano
Masahiro
M
Yamashita
Shinya
S
Nishikawa
Yasuaki
Y
Higaki
Naozumi
N
Hayashida
Hirohito
H
Niinobu
Takahiro
T
Yoshioka
Yasuo
Y
Sakon
Masato
M
D000230:Adenocarcinoma / Q000150:complications / Q000188:drug therapy / Q000532:radiotherapy / Q000628:therapy*; D000369:Aged, 80 and over; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001005:Anus Neoplasms / Q000150:complications / Q000188:drug therapy / Q000532:radiotherapy / Q000628:therapy*; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology; D008297:Male; D011788:Quality of Life; D012003:Rectal Fistula / Q000209:etiology* / Q000628:therapy; D005641:Tegafur / Q000627:therapeutic use; D013997:Time Factors; D014498:Uracil / Q000627:therapeutic use
D005641:Tegafur; D014498:Uracil