title: Clinical assessment of language development in children at age 3 years that were born preterm.
abstract: OBJECTIVE
  To evaluate the influence of gestational age and birth weight on language development and neurodevelopmental outcome at age 3 years in children born preterm.
  
  
  METHODS
  Cross sectional study including 69 children followed in our developmental outpatient clinic. Patients were consecutively included at the time of the 3 years of age appointment and stratified for birth weight (<1500 grams and between 1500-2500 grams). All patients were assessed for receptive and expressive language , Denver II and Bayley II tests and clinical neurological examination. For analysis patients were divided in two groups normal language acquisition (NLA) and delay in language acquisition (DLA).
  
  
  RESULTS
  NLA children had higher scores on mental and psychomotor (p=<0.01, p=0.012) indexes of Bayley II. Newborns with less than 1500 grams had lower scores on all Bayley scale at age 36 months (p=0.002, p=0.007 and p<0.001). Multivariate analysis suggests an association between gestational age (p=0.032), abnormal behavior (p<0.001) and delay in language acquisition. Denver test at 12 and 24 months of age was a good predictor of delayed receptive and expressive language at three years of age (p=<0.01 and p=<0.01).
  
  
  CONCLUSIONS
  Children born prematurely with low birth weight had an increased risk of language acquisition delay, and those had also lower cognitive and behavior scores when compared to NLA.
authors.affiliation: Developmental Outpatient Clinic HSL - PUCRS, Division of Neurology - Hospital São Lucas and School of Medicine Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS) Porto Alegre RS - Brazil.
authors.forename: Carolina Rizzotto
authors.initials: CR
authors.lastname: Schirmer
authors.forename: Mirna Wetters
authors.initials: MW
authors.lastname: Portuguez
authors.forename: Magda Lahorgue
authors.initials: ML
authors.lastname: Nunes
mesh_terms: D002675:Child, Preschool; D015331:Cohort Studies; D003430:Cross-Sectional Studies; D002658:Developmental Disabilities / Q000175:diagnosis / Q000209:etiology*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D007805:Language Development Disorders / Q000175:diagnosis / Q000209:etiology*; D008297:Male; D009483:Neuropsychological Tests; D047928:Premature Birth; D012307:Risk Factors