title: [Chorea].
abstract: Chorea (from the greek word "dance") is characterized by short, involuntary, irregular, nonrepetitive, adventitious muscular contractions. The resulting movements may occur abruptly at any part of the body, but may also spread from one body part to another. The most important condition showing chorea as its core symptom is Huntington's disease. It is inherited as an autosomal dominant trait. During its course it presents as an admixture of neurological and psychiatric features. Several rare neurodegenerative diseases and conditions of inborn errors of metabolism present with chorea mostly between childhood and adolescence. Among these, the paroxysmal choreoathetoses are important for the differential diagnosis of seizures and transitory ischaemic attacks later in life. In adults, symptomatic chorea may occur in many drug-induced, metabolic, infectious, immunological, toxic, and vascular conditions. In addition to the basic treatments of these illnesses there are selected drugs to provide satisfactory symptomatic relief from the abnormal movement.
authors.affiliation: Klinik für Neurologie, Klinikum Lippe, Lemgo. peter.vieregge@klinikum-lippe.de
authors.forename: P
authors.initials: P
authors.lastname: Vieregge
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000927:Anticonvulsants / Q000008:administration & dosage / Q000627:therapeutic use; D014150:Antipsychotic Agents / Q000008:administration & dosage / Q000627:therapeutic use; D001264:Athetosis / Q000175:diagnosis / Q000188:drug therapy / Q000503:physiopathology; D002648:Child; D002819:Chorea / Q000139:chemically induced / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology / Q000503:physiopathology; D003937:Diagnosis, Differential; D018492:Dopamine Antagonists / Q000008:administration & dosage / Q000627:therapeutic use; D020820:Dyskinesias / Q000175:diagnosis; D006801:Humans; D006816:Huntington Disease / Q000175:diagnosis / Q000235:genetics / Q000503:physiopathology; D008875:Middle Aged; D013469:Sulpiride / Q000008:administration & dosage / Q000627:therapeutic use; D013997:Time Factors
chemical_list: D000927:Anticonvulsants; D014150:Antipsychotic Agents; D018492:Dopamine Antagonists; D013469:Sulpiride