Congenital midline cervical cleft.
Congenital midline cervical cleft (CMCC) is a rare disorder of the ventral neck that is clinically evident at birth and must be differentiated from the more common thyroglossal duct cyst. The case of CMCC presented here was associated with chromosomes 13/14 de novo Robertsonian translocations as well as midline deformities including a sacral tuft and a minor tongue-tie. The case is presented as well as discussion of histopathology, embryology, and surgical treatment.
Agag
Richard
R
New Jersey Medical School, UMDNJ, Newark, NJ, USA.
Sacks
Justin
J
Silver
Lester
L
D002882:Chromosomes, Human, Pair 13 / Q000235:genetics; D002883:Chromosomes, Human, Pair 14 / Q000235:genetics; D003937:Diagnosis, Differential; D006801:Humans; D007223:Infant; D008035:Lingual Frenum / Q000002:abnormalities; D008297:Male; D009333:Neck / Q000002:abnormalities*; D013955:Thyroglossal Cyst / Q000175:diagnosis; D014178:Translocation, Genetic / Q000235:genetics