title: [A case of effective chemoradiation therapy against anal fistula carcinoma recurred 10 years after surgery].
abstract: A male in his eighties underwent abdominoperineal resection under the diagnosis of adenocarcinoma associated with anal fistula (P0, H0, n (-), A1, stage II, ly0, v0). Ten years after the surgery, a painful lymph node swelling was noticed in the left inguinal region. Biopsy specimen showed adenocarcinoma consisting of severe dysplastic cells. Radiotherapy was performed in the pelvic region at a total dose of 50 Gy (2 Gy/day). After the radiotherapy, left inguinal and pelvic lymph nodes markedly shrank and became painless. After one month, the chemotherapy with UFT (UFT 300 mg/day) was started. One year thereafter, para-aortic lymph nodes were found to be enlarged, but a good quality of life was obtained without elevation of tumor markers.
authors.affiliation: Dept, of Surgery, Nishinomiya Municipal Central Hospital.
authors.forename: Sumiko
authors.initials: S
authors.lastname: Nakagawa
authors.forename: Masahiro
authors.initials: M
authors.lastname: Amano
authors.forename: Shinya
authors.initials: S
authors.lastname: Yamashita
authors.forename: Yasuaki
authors.initials: Y
authors.lastname: Nishikawa
authors.forename: Naozumi
authors.initials: N
authors.lastname: Higaki
authors.forename: Hirohito
authors.initials: H
authors.lastname: Hayashida
authors.forename: Takahiro
authors.initials: T
authors.lastname: Niinobu
authors.forename: Yasuo
authors.initials: Y
authors.lastname: Yoshioka
authors.forename: Masato
authors.initials: M
authors.lastname: Sakon
mesh_terms: D000230:Adenocarcinoma / Q000150:complications / Q000188:drug therapy / Q000532:radiotherapy / Q000628:therapy*; D000369:Aged, 80 and over; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001005:Anus Neoplasms / Q000150:complications / Q000188:drug therapy / Q000532:radiotherapy / Q000628:therapy*; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology; D008297:Male; D011788:Quality of Life; D012003:Rectal Fistula / Q000209:etiology* / Q000628:therapy; D005641:Tegafur / Q000627:therapeutic use; D013997:Time Factors; D014498:Uracil / Q000627:therapeutic use
chemical_list: D005641:Tegafur; D014498:Uracil