title: Trigeminal autonomic cephalgias due to structural lesions: a review of 31 cases.
abstract: Trigeminal autonomic cephalgias (TACs) include cluster headache, paroxysmal hemicrania, and short-lasting unilateral neuralgiform headache with conjunctival injection and tearing. Associated structural lesions may be found, but a causal relationship is often difficult to establish. We sought to identify clinical predictors of underlying structural abnormalities by reviewing previously described and new TAC and TAC-like cases associated with a structural lesion. We found that even typical TACs can be caused by an underlying lesion. Clinical warning signs and symptoms are relatively rare. We recommend neuroimaging in all patients with a TAC or TAC-like syndrome.
authors.affiliation: Department of Neurology, Leiden University Medical Centre, Leiden, The Netherlands. i.favier@lumc.nl
authors.forename: Irene
authors.initials: I
authors.lastname: Favier
authors.forename: Jorine A
authors.initials: JA
authors.lastname: van Vliet
authors.forename: Krista I
authors.initials: KI
authors.lastname: Roon
authors.forename: Ron J W
authors.initials: RJ
authors.lastname: Witteveen
authors.forename: Jan J G M
authors.initials: JJ
authors.lastname: Verschuuren
authors.forename: Michel D
authors.initials: MD
authors.lastname: Ferrari
authors.forename: Joost
authors.initials: J
authors.lastname: Haan
mesh_terms: D000328:Adult; D001930:Brain Injuries / Q000150:complications* / Q000473:pathology; D003952:Diagnostic Imaging; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D039781:PubMed / Q000706:statistics & numerical data; D051303:Trigeminal Autonomic Cephalalgias / Q000145:classification / Q000453:epidemiology / Q000209:etiology* / Q000473:pathology*