title: Effect of profenofos feeding on biochemical changes in chicken.
abstract: The disruption of transaminases and phosphatases from the normal values denotes biochemical impairment and lesions of tissues and cellular function because they are involved in the detoxification process, metabolism and biosynthesis of energetic macromolecules for different essential function. The results of the present study revealed that feeding chicken in profenofos contaminated feed at levels of 50, 100 and 200 ppm for three weeks, resulted in a significant increase in the values of glutamic-pyruvic transaminase (GPT), glutamic oxaloacetic transaminase (GOT), Alkaline phosphatase (A.P.) and cholesterol, especially at levels of 100 and 200 ppm. Upon return of normal feed free from profenofos for 10 days, these values decreased gradually but not to normal and the decreases were not significant.
authors.affiliation: Animal Health Research Institute, Cairo.
authors.lastname: Azza
authors.forename: M
authors.initials: M
authors.lastname: Aboul el Wafa
authors.forename: T
authors.initials: T
authors.lastname: Abdel-Azize
authors.lastname: Eglal
authors.forename: E A
authors.initials: EA
authors.lastname: Salem
mesh_terms: D000410:Alanine Transaminase / Q000187:drug effects; D000469:Alkaline Phosphatase / Q000187:drug effects; D000821:Animal Feed / Q000633:toxicity*; D000818:Animals; D001219:Aspartate Aminotransferases / Q000187:drug effects; D002645:Chickens; D002784:Cholesterol; D005506:Food Contamination; D007306:Insecticides / Q000494:pharmacology / Q000633:toxicity*; D010755:Organophosphates / Q000378:metabolism / Q000633:toxicity*; D063086:Organothiophosphates / Q000378:metabolism / Q000633:toxicity*
chemical_list: D007306:Insecticides; D010755:Organophosphates; D063086:Organothiophosphates; C024273:profenofos; D002784:Cholesterol; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase; D000469:Alkaline Phosphatase