[Study on correlation between HPV57 infection and the etiology of IP].
OBJECTIVE
To study correlation between HPV infection and the etiology of human papilloma and uncover the effects of HPV57 infection on IP, in order to provide a new way for IP precaution and treatment.


METHODS
Sixty formalin-fixed, paraffin-embedded specimens of IP were definitely diagnosed by pathologists. They were examined by the polymerase chain reaction (PCR) technique to amplify HPV DNA with HPV L1 consensus primer and HPV57 type-specific primer. Ten specimens of chronic sinusitis were taken as control group.


RESULTS
All of the sixty IP specimens showed negative after amplification by HPV 1.1 consensus primer MY09/11. There were forty-seven specimens(47/60, 78.3%) showed positive for HPV type 57 after amplification by HPV57 type-specific primer.


CONCLUSIONS
Our findings suggest a possible role for HPV type 57 in the pathogenesis of nasal inverted papilloma.
Guan
Ya feng
Yf
Department of Otorhinolaryngology, Ningbo Medical Center LI Huili Hospital, Ningbo, 315041, China. entguan@21cn.com
Zang
Chaoping
C
Zhang
Chonghua
C
D006801:Humans; D009669:Nose Neoplasms / Q000473:pathology / Q000821:virology*; D018308:Papilloma, Inverted / Q000473:pathology / Q000821:virology*; D027383:Papillomaviridae / Q000302:isolation & purification; D030361:Papillomavirus Infections