[Biochemical basic of alcoholic liver injury].
The liver is the main place of ethanol oxidation and is especially sensitive to the toxic effects of alcohol. Alcoholic liver disease is caused by chronic alcohol abuse. The article presents the negative effect of alcohol and its metabolites on the different biochemical processes in the liver.
Jelski
Wojciech
W
Akademia Medyczna w Białymstoku, Zakład Diagnostyki Biochemicznej.
Chrostek
Lech
L
Szmitkowski
Maciej
M
D000079:Acetaldehyde / Q000378:metabolism / Q000494:pharmacology; D000426:Alcohol Dehydrogenase / Q000378:metabolism*; D000437:Alcoholism / Q000150:complications*; D000818:Animals; D019392:Cytochrome P-450 CYP2E1 / Q000378:metabolism*; D000431:Ethanol / Q000633:toxicity; D005235:Fatty Liver, Alcoholic / Q000201:enzymology; D006519:Hepatitis, Alcoholic / Q000201:enzymology; D006801:Humans; D008099:Liver / Q000187:drug effects* / Q000378:metabolism; D008104:Liver Cirrhosis, Alcoholic / Q000201:enzymology; D008108:Liver Diseases, Alcoholic / Q000209:etiology* / Q000378:metabolism*
D000431:Ethanol; D000426:Alcohol Dehydrogenase; D019392:Cytochrome P-450 CYP2E1; D000079:Acetaldehyde