title: MRI investigation for neurofibromatosis type 1 lesions during pregnancy--a case report.
abstract: BACKGROUND
  Neurofibromatosis type 1 (NF1) is a genetic disorder of the nervous system that causes tumor growth on the nerves, skin changes and bone deformities, and it is reported to be associated with adverse perinatal outcome in pregnant women.
  
  
  METHODS
  We report a case of MRI investigation of a pregnant woman with a known NF1 disease who showed exacerbation of skin lesions during pregnancy. No dangerous lesions that could compromise pregnancy outcome were detected, thus allowing the pregnancy to continue to term uneventfully.
  
  
  CONCLUSIONS
  MRI has strong indications for the follow-up of pregnant patients with neurofibromatosis as it can detect lesions that can serve as risk factors for pregnancy complications.
authors.affiliation: 1st Department of Obstetrics and Gynecology "Alexandra Maternity Hospital", University of Athens, Athens, Greece.
authors.forename: K
authors.initials: K
authors.lastname: Stefanidis
authors.forename: E
authors.initials: E
authors.lastname: Solomou
authors.forename: E
authors.initials: E
authors.lastname: Lagona
authors.forename: A
authors.initials: A
authors.lastname: Pilalis
authors.forename: N
authors.initials: N
authors.lastname: Makris
authors.forename: D
authors.initials: D
authors.lastname: Loutradis
authors.forename: A
authors.initials: A
authors.lastname: Antsaklis
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D009456:Neurofibromatosis 1 / Q000473:pathology*; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000473:pathology*