title: Time course of axonal regeneration in acute motor axonal neuropathy.
abstract: Patients with acute motor axonal neuropathy (AMAN) generally recover well. We reviewed clinical and electrophysiologic recovery in 13 patients for up to 5 years. Twelve patients showed rapid recovery over 12 months, whereas in the remaining one the recovery was slow and incomplete at 5 years. In AMAN, axonal degeneration appears to develop predominantly in the motor nerve terminals, and only occasionally more proximally in the nerve roots. Nerve terminal degeneration-regeneration presumably provides a mechanism for good recovery.
authors.affiliation: Department of Neurology, Chiba University School of Medicine, 1-8-1 Inohana, Chuo-ku, Chiba 260-8670, Japan.
authors.forename: Noriko
authors.initials: N
authors.lastname: Tamura
authors.forename: Satoshi
authors.initials: S
authors.lastname: Kuwabara
authors.forename: Sonoko
authors.initials: S
authors.lastname: Misawa
authors.forename: Kazuaki
authors.initials: K
authors.lastname: Kanai
authors.forename: Miho
authors.initials: M
authors.lastname: Nakata
authors.forename: Setsu
authors.initials: S
authors.lastname: Sawai
authors.forename: Masahiro
authors.initials: M
authors.lastname: Mori
authors.forename: Takamichi
authors.initials: T
authors.lastname: Hattori
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001369:Axons / Q000473:pathology; D018450:Disease Progression; D004576:Electromyography; D005260:Female; D020275:Guillain-Barre Syndrome / Q000175:diagnosis / Q000473:pathology / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009046:Motor Neurons / Q000473:pathology; D009416:Nerve Regeneration; D009431:Neural Conduction; D010525:Peripheral Nerves / Q000473:pathology / Q000503:physiopathology*; D017729:Presynaptic Terminals / Q000473:pathology; D020127:Recovery of Function; D013997:Time Factors; D014855:Wallerian Degeneration / Q000209:etiology / Q000473:pathology / Q000503:physiopathology