title: Influence of motor symptoms upon the quality of life of patients with Parkinson's disease.
abstract: We studied the impact of various motor and nonmotor symptoms upon quality of life in patients with Parkinson's disease (PD). The study comprised 110 patients with PD (age: 68.6 years, course of the disease: 7.6 years). The Unified Parkinson Disease Rating Scale (UPDRS; I-IV) and Parkinson's Disease Questionnaire (PDQ-39) were recorded. We recorded the correlations between years of disease and UPDRS IV, as well as PDQ-39 and UPDRS I, II, III and IV. Introduction of all variables into a linear regression model showed that 3 variables accounted for 51% of the variance in PDQ-39. Mental condition, gait disorders and complications of dopaminergic drugs are the variables that most affect the quality of life of patients with PD.
authors.affiliation: Neurology Service, Movement Disorders Unit, Hospital of Cruces, Baracaldo, and Neurosciences Department, Basque Country University, Bilbao, Spain. jgomeze@meditex.es
authors.forename: J C
authors.initials: JC
authors.lastname: Gómez-Esteban
authors.forename: J J
authors.initials: JJ
authors.lastname: Zarranz
authors.forename: E
authors.initials: E
authors.lastname: Lezcano
authors.forename: B
authors.initials: B
authors.lastname: Tijero
authors.forename: A
authors.initials: A
authors.lastname: Luna
authors.forename: F
authors.initials: F
authors.lastname: Velasco
authors.forename: I
authors.initials: I
authors.lastname: Rouco
authors.forename: I
authors.initials: I
authors.lastname: Garamendi
mesh_terms: D000368:Aged; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D016014:Linear Models; D008297:Male; D008875:Middle Aged; D009069:Movement Disorders / Q000209:etiology*; D010300:Parkinson Disease / Q000503:physiopathology* / Q000523:psychology*; D011788:Quality of Life; D012720:Severity of Illness Index; D018434:Sickness Impact Profile; D011795:Surveys and Questionnaires