title: Achieving tight glycaemic control.
abstract: The implementation of tight glycaemic control (TGC) is becoming accepted best practice within intensive care units throughout the world. It is recommended by the Surviving Sepsis Campaign and is included in the sepsis care bundle. The major impact of TGC is currently thought to be associated with reduced morbidity and mortality. The process of achieving TGC is, however, not without risk. In particular, the need for frequent, accurate blood glucose measurement and the possibility of prolonged, unrecognised hypoglycaemia are of concern. There is also the potential for patients who exhibit significant insulin resistance to require the administration of large amounts of insulin. The transfer of patients from the intensive care unit to the operating theatre or for computerised tomography during intensive insulin therapy is also hazardous. The purpose of this paper is to describe a series of nurse led pilot studies which aimed to introduce the process of TGC whilst maintaining patient safety. The results demonstrate the effectiveness of a staged approach and the achievement of TGC.
authors.affiliation: Royal Free Hampstead NHS Trust, London, UK. Carol.Ball@royalfree.nhs.uk <Carol.Ball@royalfree.nhs.uk>
authors.forename: Carol
authors.initials: C
authors.lastname: Ball
authors.forename: Karen
authors.initials: K
authors.lastname: de Beer
authors.forename: Amanda
authors.initials: A
authors.lastname: Gomm
authors.forename: Barbara
authors.initials: B
authors.lastname: Hickman
authors.forename: Peta
authors.initials: P
authors.lastname: Collins
mesh_terms: D000465:Algorithms; D019985:Benchmarking / Q000379:methods; D001786:Blood Glucose / Q000378:metabolism; D002985:Clinical Protocols; D003422:Critical Care / Q000379:methods*; D016903:Drug Monitoring / Q000451:nursing; D019983:Guideline Adherence; D006301:Health Services Needs and Demand; D006801:Humans; D006943:Hyperglycemia / Q000097:blood / Q000175:diagnosis / Q000517:prevention & control*; D007003:Hypoglycemia / Q000097:blood / Q000175:diagnosis / Q000517:prevention & control*; D007004:Hypoglycemic Agents / Q000009:adverse effects / Q000627:therapeutic use*; D007328:Insulin / Q000009:adverse effects / Q000627:therapeutic use*; D007333:Insulin Resistance; D024802:Nurse's Role; D009730:Nursing Assessment; D015403:Nursing Evaluation Research; D009741:Nursing Staff, Hospital; D010865:Pilot Projects; D017410:Practice Guidelines as Topic; D012307:Risk Factors; D017751:Safety Management / Q000379:methods*; D014187:Transportation of Patients
chemical_list: D001786:Blood Glucose; D007004:Hypoglycemic Agents; D007328:Insulin