[FT-Raman spectroscopic investigation on hypothyroid cancer].
The normal and malignant tissues from hypothyroid were investigated by FT-Raman spectroscopy. The results show that two characteristic Raman spectral peaks of normal tissues appeared at 503 and 758 cm(-1) (corresponding to theextension vibration of C--I band and the vibration of benzene rings respectively) in the range of 400-3500 cm(-1). The two peaks disappeared at malignant tissues. The intensity of the characteristic vibration peaks of normal tissues appearing at 3 062 and 1 003 cm(-1) corresponding to tyrosine weakened in malignant tissues. Thus, FT-Raman spectroscopy is a potential method in the diagnosis of hypothyroid cancer.
Li
Rong
R
Department of Chemistry, Guiyang Medical College, Guiyang 550004, China.
Zhou
Guang-ming
GM
Peng
Hong-jun
HJ
Deng
Yong-li
YL
D006801:Humans; D013059:Spectrum Analysis, Raman / Q000379:methods*; D013964:Thyroid Neoplasms / Q000175:diagnosis*