title: Biosynthesis of the thioquinolobactin siderophore: an interesting variation on sulfur transfer.
abstract: The thioquinolobactin siderophore from Pseudomonas fluorescens ATCC 17400 utilizes a variation of the sulfur transfer chemistry found in thiamine and molydobterin biosynthesis. A JAMM motif protein cleaves the C-terminal amino acid residues following a diglycine moiety on a small sulfur carrier protein, and the modified C terminus is activated and sulfurylated, forming a thiocarboxylate.
authors.affiliation: Department of Chemistry and Chemical Biology, Cornell University, Ithaca, NY 14853, USA.
authors.forename: Amy M
authors.initials: AM
authors.lastname: Godert
authors.forename: Mi
authors.initials: M
authors.lastname: Jin
authors.forename: Fred W
authors.initials: FW
authors.lastname: McLafferty
authors.forename: Tadhg P
authors.initials: TP
authors.lastname: Begley
mesh_terms: D011551:Pseudomonas fluorescens / Q000378:metabolism*; D011804:Quinolines / Q000378:metabolism*; D021241:Spectrometry, Mass, Electrospray Ionization; D013455:Sulfur / Q000378:metabolism*
chemical_list: D011804:Quinolines; C518370:thioquinolobactin; D013455:Sulfur