Audiovestibular disturbance in patients with systemic lupus erythematosus.
OBJECTIVE
The aim of this study was to evaluate the audiovestibular disturbance in patients with systemic lupus erythematosus (SLE).


METHODS
Twenty-eight patients with SLE and 28 healthy control subjects were included. Pure-tone audiometry, impedance audiometry, and electronystagmography (ENG) were used for baseline evaluation. Laboratory tests were carried out. Cranial and brain stem magnetic resonance imagings (MRI) were undertaken.


RESULTS
Nineteen (67%) patients reported audiovestibular symptoms. Sensorineural hearing loss was found in 6 (21%) patients. Abnormal results on ENG were significantly higher (50%) (P < 0.01). Abnormal laboratory data were available from 26 patients (P < 0.05). MRI did not show any pathosis.


CONCLUSIONS
The audiovestibular disturbances in SLE are more prevalent than previously recognized. Although no cause and effect relationship can be established by this type of study, it appears that a relationship exists.


CONCLUSIONS
Audiologic research should be directed toward routine, pure tone audiometry, and ENG assessment for patients with SLE to enable crucial treatment.
Karatas
Erkan
E
Department of Otolaryngology-Head and Neck Surgery, Faculty of Medicine, Gaziantep University, Gaziantep, Turkey. erkaratas@yahoo.com
Onat
Ahmet Mesut
AM
Durucu
Cengiz
C
Baglam
Tekin
T
Kanlikama
Muzaffer
M
Altunoren
Orcun
O
Buyukhatipoglu
Hakan
H
D000293:Adolescent; D000328:Adult; D000368:Aged; D001301:Audiometry, Pure-Tone; D004584:Electronystagmography; D005260:Female; D006319:Hearing Loss, Sensorineural / Q000097:blood / Q000175:diagnosis / Q000209:etiology; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000097:blood / Q000150:complications*; D008279:Magnetic Resonance Imaging; D008297:Male; D009759:Nystagmus, Pathologic / Q000097:blood / Q000209:etiology; D011446:Prospective Studies; D014012:Tinnitus / Q000097:blood / Q000209:etiology*; D014717:Vertigo / Q000097:blood / Q000209:etiology*; D020338:Vestibular Neuronitis / Q000097:blood / Q000209:etiology*