title: New insight into the mechanism of methyl transfer during the biosynthesis of fosfomycin.
abstract: Hydroxyethylphosphonate is a required intermediate in fosfomycin biosynthesis.
authors.affiliation: Department of Chemistry, University of Illinois at Urbana-Champaign, 600 S Mathews Ave, Urbana, IL 61801, USA.
authors.forename: Ryan D
authors.initials: RD
authors.lastname: Woodyer
authors.forename: Gongyong
authors.initials: G
authors.lastname: Li
authors.forename: Huimin
authors.initials: H
authors.lastname: Zhao
authors.forename: Wilfred A
authors.initials: WA
authors.lastname: van der Donk
mesh_terms: D005578:Fosfomycin / Q000096:biosynthesis* / Q000737:chemistry*; D008745:Methylation; D008780:Methyltransferases / Q000378:metabolism; D015394:Molecular Structure; D063065:Organophosphonates / Q000737:chemistry; D048170:Streptomyces lividans / Q000737:chemistry / Q000235:genetics / Q000378:metabolism
chemical_list: C519566:2-hydroxyethyl phosphonate; D063065:Organophosphonates; D005578:Fosfomycin; D008780:Methyltransferases