Diversely substituted sugar-linked alpha,beta-unsaturated gamma-lactones from sugar-derived Baylis-Hillman adducts via a RCM.
A versatile protocol for the production of sugar-linked alpha,beta-unsaturated gamma-lactones with stereochemical and functional group diversity is described starting from sugar-derived Baylis-Hillman adducts via ring-closing metathesis.
Krishna
Palakodety Radha
PR
D-206/B, Discovery Laboratory, Organic Chemistry Division III, Indian Institute of Chemical Technology, Hyderabad-500 007, India. prkgenius@iict.res.in
Narsingam
M
M
D000475:Alkenes / Q000138:chemical synthesis* / Q000737:chemistry; D002241:Carbohydrates / Q000138:chemical synthesis* / Q000737:chemistry; D020650:Combinatorial Chemistry Techniques / Q000379:methods; D007783:Lactones / Q000138:chemical synthesis* / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D009904:Optical Rotation; D021241:Spectrometry, Mass, Electrospray Ionization; D013055:Spectrophotometry, Infrared; D013237:Stereoisomerism
D000475:Alkenes; D002241:Carbohydrates; D007783:Lactones