Primary cerebellopontine angle craniopharyngioma in a patient with gardner syndrome. Case report and review of the literature.
The authors report on the case of a craniopharyngioma arising in the cerebellopontine angle (CPA) in a patient with Gardner syndrome. Although familial adenomatous polyposis (FAP) is associated with intracranial neoplasms, the current case is only the third reported craniopharyngioma in a patient with Gardner syndrome. Two of these tumors, including that of the current case, originated in the CPA, an unusual location for craniopharyngiomas. The literature concerning FAP and its associations with intracranial neoplasia, as well as the pathogenesis of craniopharyngiomas in the posterior fossa, is discussed.
Aquilina
Kristian
K
Department of Neurosurgery, Beaumont Hospital, Dublin, Ireland. kristianaquilina@hotmail.com
O'Brien
Donncha F
DF
Farrell
Michael A
MA
Bolger
Ciaran
C
D000328:Adult; D002528:Cerebellar Neoplasms / Q000175:diagnosis / Q000235:genetics* / Q000473:pathology / Q000601:surgery*; D002530:Cerebellopontine Angle / Q000473:pathology* / Q000601:surgery*; D002531:Cerebellum / Q000473:pathology / Q000601:surgery; D003397:Craniopharyngioma / Q000175:diagnosis / Q000235:genetics / Q000473:pathology / Q000601:surgery*; D003937:Diagnosis, Differential; D005350:Fibroma / Q000175:diagnosis / Q000235:genetics / Q000473:pathology / Q000601:surgery; D005736:Gardner Syndrome / Q000175:diagnosis / Q000235:genetics / Q000473:pathology / Q000601:surgery*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009378:Neoplasms, Multiple Primary / Q000175:diagnosis / Q000235:genetics / Q000473:pathology / Q000601:surgery; D012535:Scalp / Q000473:pathology / Q000601:surgery; D012878:Skin Neoplasms / Q000175:diagnosis / Q000235:genetics / Q000473:pathology / Q000601:surgery