[A randomized controlled trial of Yiqi Pingchuan Granule in treating acute attack of bronchial spasm due to asthma of qi deficiency and cold syndrome].
OBJECTIVE
To evaluate the safety and efficacy of Yiqi Pingchuan Granule in treating acute attack of asthma due to qi deficiency and cold syndrome.


METHODS
A randomized controlled trial was conducted. A total of 80 patients with an acute attack of asthma were included. They were allocated into two groups randomly in a ratio of three to one. Sixty patients in the treatment group received Yiqi Pingchuan Granule and 20 patients in the control group received Ruyi Dingchuan Pill. Patients in both groups were treated for 7 days.


RESULTS
There were no significant differences in traditional Chinese medicine syndrome, clinical symptoms and lung function between the two groups (P>0.05). After treatment, the forced expiratory volume in 1 second was increased in the treatment group (P<0.05), and the peak expiratory flow was accelerated in the control group (P<0.05). No significant side effects were noted in both groups.


CONCLUSIONS
Yiqi Pingchuan Granule is safe and effective in treating acute attack of asthma due to qi deficiency and cold syndrome.
Zhang
Ying
Y
Department of Integrated Traditional Chinese and Western Medicine, West China Hospital, Sichuan University, Chengdu, Sichuan Province 610041, China.
Zhang
Rui-ming
RM
Chang
Jing
J
Li
Ting-qian
TQ
Chi
Huan-hai
HH
Mao
Bing
B
Chen
Guang-yuan
GY
Tang
Wen-fu
WF
Wang
Lei
L
Huang
Su-zhen
SZ
D000328:Adult; D001249:Asthma / Q000150:complications / Q000188:drug therapy*; D001986:Bronchial Spasm / Q000188:drug therapy* / Q000209:etiology / Q000503:physiopathology; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D005541:Forced Expiratory Volume / Q000187:drug effects; D006801:Humans; D008297:Male; D008516:Medicine, Chinese Traditional; D008875:Middle Aged; D008517:Phytotherapy; D019413:Qi; D013577:Syndrome; D016896:Treatment Outcome; D016711:Yang Deficiency / Q000150:complications / Q000188:drug therapy* / Q000473:pathology
D004365:Drugs, Chinese Herbal; C521735:pingchuan yiqi