title: Gender variation in ocular biometry and ultrasound biomicroscopy of primary angle closure suspects and normal eyes.
abstract: OBJECTIVE
  To compare A-scan biometry and ultrasound biomicroscopy of primary angle closure suspects (PACS) with age-matched normal Indian eyes.
  
  
  METHODS
  Subjects with primary angle closure suspects (n=57 eyes) and normal eyes (n=57 eyes) underwent A-scan biometry and ultrasound biomicroscopy. Anterior chamber depth (ACD), anterior chamber angle (ACA), axial length (AXL), lens thickness, relative lens position (RLP), central corneal thickness (CCT), angle opening distance 500, trabecular-ciliary process distance (TCPD), iris-ciliary process distance, iris thickness, and scleral-ciliary process angle were measured. The subjects were divided into males, females, and combined groups for analysis. The parameters were compared using independent sample t test with Bonferroni correction for multiple comparisons.
  
  
  RESULTS
  In the combined group, the PACS subjects presented a significantly low ACD, AXL, CCT, AOD500, TCPD, ACA (P<0.001), and RLP (P=0.04). In males, RLP was anterior (P=0.002) and in females, the lens thickness (P<0.001) was significantly thicker among the PACS group.
  
  
  CONCLUSIONS
  ACD, AXL, CCT, TCPD, ACA, and angle opening distance 500 of the PACS group were significantly lower than in normals. In females, the lens in PACS was thicker than in normals. Lens in males was more anterior-placed in PACS group than in normals.
authors.affiliation: Sankara Nethralaya, Unit of Medical Research Foundation, 18 College road, Chennai 600 006, India.
authors.forename: Krishna Kumar
authors.initials: KK
authors.lastname: Ramani
authors.forename: Baskaran
authors.initials: B
authors.lastname: Mani
authors.forename: George
authors.initials: G
authors.lastname: Ronnie
authors.forename: Roy
authors.initials: R
authors.lastname: Joseph
authors.forename: Vijaya
authors.initials: V
authors.lastname: Lingam
mesh_terms: D000869:Anterior Eye Segment / Q000000981:diagnostic imaging*; D001699:Biometry; D001837:Body Weights and Measures; D005123:Eye / Q000000981:diagnostic imaging*; D005260:Female; D015812:Glaucoma, Angle-Closure / Q000000981:diagnostic imaging*; D006068:Gonioscopy; D006801:Humans; D007908:Lens, Crystalline / Q000000981:diagnostic imaging*; D008297:Male; D033401:Microscopy, Acoustic; D008875:Middle Aged; D012737:Sex Factors