Effects of exercise intervention on patients with stroke with prior coronary artery disease: aerobic capacity, functional ability, and lipid profile: a pilot study.
OBJECTIVE
To assess the effects of exercise intervention on aerobic capacity, functional ability and lipid profile in patients after stroke with prior coronary artery disease.


METHODS
Fifteen patients after stroke with prior coronary artery disease.


METHODS
Patients were enrolled in a moderate-intensity exercise intervention using a graded treadmill for 12 weeks. Before and after the intervention, their aerobic capacity and functional ability were assessed by the exercise testing and Barthel index, respectively. The total cholesterol (TC), lowdensity lipoprotein cholesterol (LDL), high-density lipoprotein cholesterol (HDL), triglyceride, and TC/HDL were also evaluated using an enzyme auto-analyser.


RESULTS
After training, the patients'absolute peak oxygen consumption (VO2) was increased (p < 0.01); their functional ability was significantly improved (p < 0.01); and their TC, LDL, triglyceride, and TC/HDL levels were significantly reduced (p < 0.01). However, HDL level did not change significantly. In addition, Pearson analysis demonstrated a strong correlation between the increase in peak VO2 and the decrease in TC/HDL (r = -0.72, p < 0.01).


CONCLUSIONS
These results suggest that exercise intervention is beneficial for aerobic capacity, functional ability, and some parts of the lipid profile in patients after stroke with prior coronary artery disease.
Yang
Ai-Lun
AL
Department of Physical Therapy, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Lee
Shin-Da
SD
Su
Chia-Ting
CT
Wang
Jue-Long
JL
Lin
Ko-Long
KL
D000203:Activities of Daily Living; D000368:Aged; D003327:Coronary Disease / Q000150:complications; D004185:Disability Evaluation; D005080:Exercise Test; D005081:Exercise Therapy; D005260:Female; D006801:Humans; D008055:Lipids / Q000097:blood; D008297:Male; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000150:complications; D010101:Oxygen Consumption; D010865:Pilot Projects; D011379:Prognosis; D020521:Stroke / Q000209:etiology / Q000503:physiopathology; D000071939:Stroke Rehabilitation; D016896:Treatment Outcome
D008055:Lipids