[Blood pressure changes post liver transplantation in 206 recipients].
OBJECTIVE
To study the blood pressure (BP) changes in the liver transplant recipients.


METHODS
A total of 206 patients without preoperation hypertension received liver transplantation in our hospital from February 2001 to July 2005. The BP level and serum immunosuppressant concentration at preoperation and various time points post operation were determined.


RESULTS
Compared with the preoperation, the average systolic and diastolic pressure was significantly increased at the 2 week, 1, 2, 4 and 6 months post operation. The mobility of hypertension increased significantly after liver transplantation, with the highest mobility (46.49%) at the 1st month post operation. There was no linear correlation between the immunosuppressant (FK506) concentration and the BP level at any time point.


CONCLUSIONS
There was a high hypertension incidence after liver transplantation. Although the use of immunosuppressive drugs accompanied with the BP increase, there was no linear correlation between the immunosuppressant concentration and the BP level post operation.
Liu
Hai
H
First People's Hospital, Shanghai Jiaotong University, Shanghai 200080, China.
Dai
Qiu-yan
QY
Peng
Zhi-hai
ZH
Sun
Bao-gui
BG
D001794:Blood Pressure; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006973:Hypertension / Q000209:etiology*; D007166:Immunosuppressive Agents / Q000009:adverse effects; D016031:Liver Transplantation / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000503:physiopathology; D012189:Retrospective Studies
D007166:Immunosuppressive Agents