title: Synthesis of 2-epi-amphidinolide E: an unexpected and highly selective C(2)inversion during an esterification reaction.
abstract: A synthesis of 2-epi-amphidinolide E (1) has been accomplished via an unexpected and highly diastereoselective C(2) stereochemical inversion during the modified Yamaguchi esterification of alcohol 4b and Fe(CO)3-complexed dienoic acid 7. [reaction: see text].
authors.affiliation: Departments of Chemistry and Biochemistry, Scripps Florida, Jupiter, Florida 33458, USA.
authors.forename: Porino
authors.initials: P
authors.lastname: Va
authors.forename: William R
authors.initials: WR
authors.lastname: Roush
mesh_terms: D019086:Bridged Bicyclo Compounds, Heterocyclic / Q000138:chemical synthesis* / Q000737:chemistry; D004951:Esterification; D008968:Molecular Conformation; D013237:Stereoisomerism; D000097442:Amphidinolides
chemical_list: D019086:Bridged Bicyclo Compounds, Heterocyclic; C452448:amphidinolide E; D000097442:Amphidinolides