Evaluation of the effect of endometriosis on oocyte quality and endometrial environment by comparison of donor and recipient outcomes following embryo transfer in a shared oocyte program.
OBJECTIVE
To determine whether endometriosis has an effect on the uterine environment vs the oocyte itself.


METHODS
A retrospective study comparing pregnancy outcome of infertile donors sharing oocytes with donor egg recipients according to whether the donor or recipient had endometriosis or not was carried out.


RESULTS
There were 26 transfers from donors with endometriosis vs 144 in donors without endometriosis. The clinical and viable PRs and implantation rates were 42.9%, 38.1%, and 29.4% for the endometriosis group vs 60.9%, 51.9%, and 33.2%, respectively, for donors without endometriosis (p = NS). The clinical and viable PRs and implantation rates for donors with endometriosis per ET was 41.2%, 35.3%, and 20.4% vs 50.4%, 48.0% and 28.4% for donors without endometriosis, respectively (p = NS).


CONCLUSIONS
Though no significant differences were found in donors with or without endometriosis in any parameters, there did appear to be a trend for lower PRs and implantation rates in women undergoing controlled ovarian hyperstimulation.
Katsoff
B
B
The Univ. of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School at Camden, Cooper Hospital/Univ. Medical Center Dept. of Obstetrics and Gynecology, Division of Reproductive Endocrinology and Infertility, Camden, USA.
Check
J H
JH
Davies
E
E
Wilson
C
C
D000328:Adult; D004624:Embryo Transfer; D004715:Endometriosis / Q000503:physiopathology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D009865:Oocytes / Q000502:physiology*; D011247:Pregnancy; D018873:Pregnancy Rate; D012189:Retrospective Studies; D014599:Uterus / Q000503:physiopathology*