Molecular cardiovascular imaging using scintigraphic methods.
Molecular cardiovascular imaging plays an increasingly important role both in basic research and in clinical diagnosis. Scintigraphic methods have long been used to study pathophysiological changes on a cellular and molecular level, and they are likely to remain important molecular imaging modalities in the foreseeable future. This article provides an overview over current developments in cardiovascular molecular imaging using scintigraphic methods. The focus lies on imaging of cardiac innervation, plaque instability, hypoxia and angiogenesis, gene expression and stem and progenitor cell migration and proliferation.
Stegger
Lars
L
Department of Nuclear Medicine, University Hospital of Münster, Albert-Schweitzer-Str. 33, 48149 Münster, Germany. stegger@uni-muenster.de
Schäfers
Klaus
K
Kopka
Klaus
K
Wagner
Stefan
S
Hermann
Sven
S
Kies
Peter
P
Law
Marilyn
M
Schober
Otmar
O
Schäfers
Michael
M
D000818:Animals; D001341:Autonomic Nervous System / Q000000981:diagnostic imaging*; D002318:Cardiovascular Diseases / Q000000981:diagnostic imaging*; D020869:Gene Expression Profiling / Q000379:methods; D006321:Heart / Q000000981:diagnostic imaging* / Q000294:innervation*; D006801:Humans; D008967:Molecular Biology; D015336:Molecular Probe Techniques; D019275:Radiopharmaceuticals; D014055:Tomography, Emission-Computed; D015899:Tomography, Emission-Computed, Single-Photon
D019275:Radiopharmaceuticals