[Study on the extraction process for salidroside and p-tyrosol in Rhodiola crenulata].
OBJECTIVE
To investigate the optimum ethanol extraction process conditions for salidroside and p-tyrosol from Rhodiola crenulata.


METHODS
The extraction rate of ethanol extract and content of salidroside and p-tyrosol were chosen as the assessment index by using the orthogonal design. The ethanol content (%), solvent quantum (fold) and extracting time (hour) were reviewed.


RESULTS
The optimum ethanol extraction process conditions were as follows: adding 6 fold of 80% ethanol, extracting for 2h and 2 times.


CONCLUSIONS
The optimum extraction process can give a reference to the research of new medicine and production of industry.
Li
Chen
C
Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000, China. chenli@lzb.ac.cn
Chen
Dong-Sheng
DS
Chen
Juan
J
Di
Duo-Long
DL
Jiang
Sheng-Xiang
SX
D002851:Chromatography, High Pressure Liquid; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification; D000431:Ethanol / Q000032:analysis / Q000302:isolation & purification; D005960:Glucosides / Q000032:analysis / Q000302:isolation & purification*; D010636:Phenols / Q000032:analysis / Q000302:isolation & purification*; D010626:Phenylethyl Alcohol / Q000031:analogs & derivatives* / Q000302:isolation & purification; D010946:Plants, Medicinal / Q000737:chemistry*; D029771:Rhodiola / Q000737:chemistry*; D013678:Technology, Pharmaceutical / Q000379:methods*; D013997:Time Factors
D004365:Drugs, Chinese Herbal; D005960:Glucosides; D010636:Phenols; C011867:4-hydroxyphenylethanol; D000431:Ethanol; C009172:rhodioloside; D010626:Phenylethyl Alcohol