o-Iodoxybenzoic acid- and tetraethylammonium bromide-mediated oxidative transformation of primary carboxamides to one-carbon dehomologated nitriles.
A clean and efficient method for the oxidative transformations of primary carboxamides to one-carbon dehomologated nitriles using the combination of o-iodoxybenzoic acid and tetraethylammonium bromide has been developed. This method exhibits a broad scope and is expected to be of great utility in organic synthesis.
Bhalerao
Dinesh S
DS
Department of Pharmaceutical Sciences & Technology, University Institute of Chemical Technology, Matunga, Mumbai-400 019, India.
Mahajan
Ulhas S
US
Chaudhari
Kiran H
KH
Akamanchi
Krishnacharya G
KG
D000577:Amides / Q000737:chemistry*; D007462:Iodobenzenes / Q000737:chemistry*; D015394:Molecular Structure; D009570:Nitriles / Q000138:chemical synthesis* / Q000737:chemistry; D010084:Oxidation-Reduction; D019789:Tetraethylammonium / Q000737:chemistry*
D000577:Amides; D007462:Iodobenzenes; D009570:Nitriles; C476101:o-iodoxybenzoic acid; D019789:Tetraethylammonium