title: Peptic ulcer disease associated with Helicobacter felis in a dog owner.
abstract: The aim of this study was to investigate the identity of the Helicobacter heilmannii-like bacteria found in the stomach of a human patient suffering from stomach ulcers and her asymptomatic pet dog. An elderly woman was referred for gastroscopy because of right hypochondrial pain, nausea, anorexia and vomiting. Gastric ulcers were observed and histology revealed the presence of multiple H. heilmannii-like bacteria. Multiplex polymerase chain reaction (PCR) identified the bacteria as H. felis. Her pet dog was also examined gastroscopically. Only mild gastric lesions were found but PCR showed the presence of H. felis as well as H. bizzozeronii and Candidatus H. heilmannii. This report associates H. felis infection in humans with severe gastric ulceration. Moreover, the suggestion can be made that the patient contracted H. felis from her dog.
authors.affiliation: Department of Pathology, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium. manuelle.debock@gmail.com
authors.forename: Manuelle
authors.initials: M
authors.lastname: De Bock
authors.forename: Kathleen
authors.initials: K
authors.lastname: Van den Bulck
authors.forename: Ann
authors.initials: A
authors.lastname: Hellemans
authors.forename: Sylvie
authors.initials: S
authors.lastname: Daminet
authors.forename: Jean-Charles
authors.initials: JC
authors.lastname: Coche
authors.forename: Jean-Claude
authors.initials: JC
authors.lastname: Debongnie
authors.forename: Annemie
authors.initials: A
authors.lastname: Decostere
authors.forename: Freddy
authors.initials: F
authors.lastname: Haesebrouck
authors.forename: Richard
authors.initials: R
authors.lastname: Ducatelle
mesh_terms: D000368:Aged; D000818:Animals; D001706:Biopsy; D004283:Dog Diseases / Q000382:microbiology / Q000635:transmission; D004285:Dogs; D005260:Female; D016481:Helicobacter Infections / Q000473:pathology / Q000635:transmission* / Q000662:veterinary; D044922:Helicobacter felis / Q000302:isolation & purification*; D006801:Humans; D013276:Stomach Ulcer / Q000382:microbiology*; D015047:Zoonoses / Q000382:microbiology