title: Effects of exercise intervention on patients with stroke with prior coronary artery disease: aerobic capacity, functional ability, and lipid profile: a pilot study.
abstract: OBJECTIVE
  To assess the effects of exercise intervention on aerobic capacity, functional ability and lipid profile in patients after stroke with prior coronary artery disease.
  
  
  METHODS
  Fifteen patients after stroke with prior coronary artery disease.
  
  
  METHODS
  Patients were enrolled in a moderate-intensity exercise intervention using a graded treadmill for 12 weeks. Before and after the intervention, their aerobic capacity and functional ability were assessed by the exercise testing and Barthel index, respectively. The total cholesterol (TC), lowdensity lipoprotein cholesterol (LDL), high-density lipoprotein cholesterol (HDL), triglyceride, and TC/HDL were also evaluated using an enzyme auto-analyser.
  
  
  RESULTS
  After training, the patients'absolute peak oxygen consumption (VO2) was increased (p < 0.01); their functional ability was significantly improved (p < 0.01); and their TC, LDL, triglyceride, and TC/HDL levels were significantly reduced (p < 0.01). However, HDL level did not change significantly. In addition, Pearson analysis demonstrated a strong correlation between the increase in peak VO2 and the decrease in TC/HDL (r = -0.72, p < 0.01).
  
  
  CONCLUSIONS
  These results suggest that exercise intervention is beneficial for aerobic capacity, functional ability, and some parts of the lipid profile in patients after stroke with prior coronary artery disease.
authors.affiliation: Department of Physical Therapy, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
authors.forename: Ai-Lun
authors.initials: AL
authors.lastname: Yang
authors.forename: Shin-Da
authors.initials: SD
authors.lastname: Lee
authors.forename: Chia-Ting
authors.initials: CT
authors.lastname: Su
authors.forename: Jue-Long
authors.initials: JL
authors.lastname: Wang
authors.forename: Ko-Long
authors.initials: KL
authors.lastname: Lin
mesh_terms: D000203:Activities of Daily Living; D000368:Aged; D003327:Coronary Disease / Q000150:complications; D004185:Disability Evaluation; D005080:Exercise Test; D005081:Exercise Therapy; D005260:Female; D006801:Humans; D008055:Lipids / Q000097:blood; D008297:Male; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000150:complications; D010101:Oxygen Consumption; D010865:Pilot Projects; D011379:Prognosis; D020521:Stroke / Q000209:etiology / Q000503:physiopathology; D000071939:Stroke Rehabilitation; D016896:Treatment Outcome
chemical_list: D008055:Lipids