title: Synthesis of new derivatives of 2,3-dihydro-7-benzo[b]furanol with potential pharmacological activity.
abstract: A series of 13 new ether-linked derivatives of 2,2-dimethyl-2.3-dihydro-7-benzofuranol have been designed and synthesized. Seven of them were evaluated for anti-HIV potency. They showed a relatively high cytotoxicity and a low anti-HIV- I activity.
authors.affiliation: Department of Medical Chemistry, Medical University of Warsaw, 3 Oczki St., 02-007 Warsaw, Poland.
authors.forename: Jerzy
authors.initials: J
authors.lastname: Kossakowski
authors.forename: Kinga
authors.initials: K
authors.lastname: Ostrowska
mesh_terms: D000478:Alkylation; D019380:Anti-HIV Agents / Q000138:chemical synthesis* / Q000494:pharmacology*; D000970:Antineoplastic Agents / Q000138:chemical synthesis* / Q000494:pharmacology*; D001572:Benzofurans / Q000138:chemical synthesis* / Q000494:pharmacology*; D004354:Drug Screening Assays, Antitumor; D006678:HIV / Q000187:drug effects; D006801:Humans; D009682:Magnetic Resonance Spectroscopy
chemical_list: D019380:Anti-HIV Agents; D000970:Antineoplastic Agents; D001572:Benzofurans