title: Supplementation of baby formula with native inulin has a prebiotic effect in formula-fed babies.
abstract: OBJECTIVE
  In this study we investigated the effects of native inulin on formula-fed babies. The influence of inulin on the microbial composition, pH, consistency and amount of faeces, and on frequency of defecation was assessed.
  
  
  METHODS
  In this study a daily dosage of 0.25 g/kg/d was used: 3 weeks of inulin consumption were inulin followed by 3 weeks without or vice versa. The study group consisted of 14 babies with an average age of 12.6 weeks (+/-6.4 weeks) and the average intake of inulin was 1.5 (+/-0.3) g/d.
  
  
  RESULTS
  The consumption of inulin increased the content of Bifidobacterium and Lactobacillus in the faeces of formula-fed babies, without affecting the number of Bacteroides or the total anaerobic count. With inulin a trend for stools becoming softer and the amount of faeces increased significantly. Frequency of defecation was not affected by the consumption of inulin. No adverse effects were reported during the periods of inulin consumption.
  
  
  CONCLUSIONS
  We conclude that with native inulin a prebiotic effect can be observed in formula-fed babies. Inulin may therefore be a useful ingredient in the formulation of baby formula to enhance the nutritional properties.
authors.affiliation: Korea Food and Nutrition Foundation, 1523 Punglim VIP-Tel, 404 Gongduk-Dong, Mapo-Gu, Seoul 121-718, Korea.
authors.forename: Sook-He
authors.initials: SH
authors.lastname: Kim
authors.forename: Da Hee
authors.initials: DH
authors.lastname: Lee
authors.forename: Diederick
authors.initials: D
authors.lastname: Meyer
mesh_terms: D001421:Bacteria, Anaerobic / Q000254:growth & development; D001644:Bifidobacterium / Q000254:growth & development; D015169:Colony Count, Microbial; D018592:Cross-Over Studies; D003672:Defecation / Q000187:drug effects* / Q000502:physiology; D005243:Feces / Q000737:chemistry / Q000382:microbiology*; D005260:Female; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007223:Infant; D041943:Infant Formula / Q000737:chemistry*; D007444:Inulin / Q000008:administration & dosage*; D007778:Lactobacillus / Q000254:growth & development; D008297:Male; D019936:Probiotics; D016896:Treatment Outcome
chemical_list: D007444:Inulin