title: Isolation, Identification, and Chemical Synthesis of 6alpha-Hydroxyraumacline: A Novel Alkaloid from Cultivated Rauwolfia serpentina Cells.
abstract: From RAUWOLFIA SERPENTINA cells cultivated in the presence of ajmaline ( 2) the new indole alkaloid, 6alpha-hydroxyraumacline ( 1), was isolated. This alkaloid also occurs in significant amounts in the nutrition medium. A simple chemical synthesis of 1 was developed starting from ajmaline ( 2).
authors.affiliation: Lehrstuhl für Pharmazeutische Biologie der Johannes Gutenberg-Universität Mainz. Institut für Pharmazie. Staudinger Weg5, D(W)-6500 Mainz. Federal Republic of Germany.
authors.forename: S
authors.initials: S
authors.lastname: Endreß
authors.forename: S
authors.initials: S
authors.lastname: Suda
authors.forename: H
authors.initials: H
authors.lastname: Takayama
authors.forename: N
authors.initials: N
authors.lastname: Aimi
authors.forename: S
authors.initials: S
authors.lastname: Sakai
authors.forename: J
authors.initials: J
authors.lastname: Stöckigt