title: A centrofacial B lymphoma in a rheumatoid arthritis patient.
abstract: We report on a 65-year-old man who was hospitalized for polyarthritis with deterioration of his general state of health and chronic sinusitis. Clinical and biological signs led to the diagnosis of RA associated with localized Wegener's granulomatosis. Methotrexate and corticosteroids led to a distinct improvement in the patient's articular symptoms and in his general condition. One year after the start of treatment, a tumefaction of the right maxillary sinus appeared. Scans revealed a tumoral lesion in the right maxillary sinus. This proved to be a large B-cell lymphoma. The patient received chemotherapy (CHOP) and radiotherapy. This centrofacial lymphoma may be regarded as a B lymphoma of the MALT (mucosal associated lymphoma tumor) type, mimicking a relapse of Wegener's granulomatosis.
authors.affiliation: Department of Rheumatology, CHU Strasbourg, 67098 Strasbourg Cedex, France; ORL, CHU Strasbourg, 67098 Strasbourg Cedex, France.
authors.forename: Christelle
authors.initials: C
authors.lastname: Sordet
authors.forename: Dalila
authors.initials: D
authors.lastname: Mrabet
authors.forename: Marc
authors.initials: M
authors.lastname: Ardizzone
authors.forename: Luc
authors.initials: L
authors.lastname: Marcellin
authors.forename: Patrick
authors.initials: P
authors.lastname: Hirschorn
authors.forename: Jean
authors.initials: J
authors.lastname: Sibilia