title: Mechanical interventions to treat acute stroke.
abstract: The approach to stroke therapy has historically been limited due to the existence of relatively few treatment options and the necessity for action within 3 hours of symptom onset. As neuroimaging technology advances, fertile new ground is revealed for novel therapies. Recently, a number of exciting mechanical systems have been developed with potential efficacy even hours after cerebrovascular occlusion: endovascular clot disruption, endovascular clot extraction, and angioplasty with stenting are currently under study, with promising initial results. With more options, each with greater effectiveness in a particular clinical scenario, the physician is now better equipped than ever to treat acute ischemic stroke successfully.
authors.affiliation: Doris and Stanley Tananbaum Stroke Center, Neurological Institute of New York, New York, NY 10032, USA.
authors.forename: David
authors.initials: D
authors.lastname: Fussell
authors.forename: H Christian
authors.initials: HC
authors.lastname: Schumacher
authors.forename: Philip M
authors.initials: PM
authors.lastname: Meyers
authors.forename: Randall T
authors.initials: RT
authors.lastname: Higashida
mesh_terms: D017130:Angioplasty / Q000379:methods*; D005343:Fibrinolytic Agents / Q000627:therapeutic use; D006801:Humans; D026741:Physical Therapy Modalities; D020521:Stroke / Q000628:therapy*; D015912:Thrombolytic Therapy / Q000379:methods; D010959:Tissue Plasminogen Activator / Q000627:therapeutic use; D014656:Vascular Surgical Procedures / Q000379:methods*
chemical_list: D005343:Fibrinolytic Agents; D010959:Tissue Plasminogen Activator