title: [Mechanisms influencing implantation of the embryo--the last-years' news].
abstract: OBJECTIVE
  To summarize recent knowledge concerning mechanisms which influence the implantation of embryo.
  
  
  METHODS
  Literature-based overview.
  
  
  METHODS
  Institute for the Care of Mother and Child, Prague. SUBJECT OF THE STUDY: Factors influencing implantation of embryo in the uterus elicit increased interest due to study of unexplained failures of embryotransfer following the successful in vitro fertilization. Our article points to recent information about physiology and pathology of mechanisms controlling implantation, namely the factors of immunity (antibodies, cells, cytokines and other mediators) whose exact regulation on the feto-maternal interface is a crucial precondition of successful implantation. Also the genetics of early embryo, as well as the possibilities of modern endoscopic techniques offer new insight onto mechanisms of implantation. Recommendations for diagnostics and treatment of implantation failure are given in the end of the article.
authors.affiliation: Institute for the Care of Mother and Child, Prague.
authors.forename: K
authors.initials: K
authors.lastname: Nouza
authors.forename: J
authors.initials: J
authors.lastname: Madar
authors.forename: E
authors.initials: E
authors.lastname: Kucera
authors.forename: M
authors.initials: M
authors.lastname: Nouza
authors.forename: M
authors.initials: M
authors.lastname: Tolarová
authors.forename: D
authors.initials: D
authors.lastname: Nováková
mesh_terms: D010064:Embryo Implantation; D004624:Embryo Transfer; D005260:Female; D006801:Humans; D007247:Infertility, Female / Q000209:etiology / Q000503:physiopathology*; D011247:Pregnancy