The road to crossovers: plants have their say.
Crossovers involve the reciprocal exchange of large fragments of genetic material between homologous chromosomes during meiosis. In this way, crossovers are the basis of genetics. Remarkably, the number and distribution of crossovers on chromosomes are closely controlled. Data from various model organisms (notably Saccharomyces cerevisiae) show that the distribution of crossovers results from a series of tightly regulated events involving the formation and repair of double-strand breaks and interference. Recent advances in genetic and cytological tools, particularly for studying Arabidopsis thaliana, have enabled crossover control in plants to be studied in more detail. In this article, we discuss the contribution of plant studies to meiosis research, particularly to our understanding of crossover control and interference, and we evaluate models of interference.
Mézard
Christine
C
Station de Génétique et d'Amélioration des Plantes, Institut Jean Pierre Bourgin, INRA, 78026 Versailles cedex, France. mezard@versailles.inra.fr
Vignard
Julien
J
Drouaud
Jan
J
Mercier
Raphaël
R
D017360:Arabidopsis / Q000235:genetics; D032461:Chromosomes, Plant; D003434:Crossing Over, Genetic / Q000502:physiology*; D008957:Models, Genetic; D015003:Yeasts / Q000235:genetics