Headspace gas chromatography-flame ionization detector method for organic solvent residue analysis in dietary supplements.
An analytical method has been developed for the identification and quantification of 20 organic solvent residues in dietary supplements. The method utilizes a headspace sampler interfaced with gas chromatography and flame ionization detection. With split injection (5:1) and a DB-624 column, most of the organic solvents are separated in 9 min. The method has been validated and was found to be relatively simple and fast, and it can be applied to most common organic solvent residues. With the mass detector, the method was able to identify organic solvents beyond the 20 standards tested.
Jeong
Mijeong Lee
ML
Unigen Pharmaceuticals, Inc., 2660 Willamette Dr NE, Lacey, WA 98516, USA. mijeongj@upi1.com
Zahn
Michael
M
Trinh
Thao
T
Jia
Qi
Q
Ma
Wenwen
W
D002849:Chromatography, Gas; D019587:Dietary Supplements / Q000032:analysis*; D008401:Gas Chromatography-Mass Spectrometry; D007202:Indicators and Reagents; D012015:Reference Standards; D015203:Reproducibility of Results; D012997:Solvents / Q000032:analysis*
D007202:Indicators and Reagents; D012997:Solvents