Preparation of amino-functionalized mesostructured cellular foams and application as hosts for large biomolecules.
Large mesopores cellular foam (LMCFs) materials were synthesized using microemulsion templating in acidic solutions. The amine functional groups were attached to channels of LMCFs materials via post-synthesis grafting. The structural and chemical properties of these prepared materials were characterized by TEM, XRD, FTIR and nitrogen adsorption. These resulting materials had disordered mesopores with well-defined large mesopore. The bovine serum albumin (BSA) and glucose oxidase (GOx) were used for adsorption experiment. The biomolecule was immobilized by covalently couple to the interior surface of amino-functionalized mesostructured cellular foams (AF-MCFs). The results showed that AF-MCFs had high-capacity bioimmobilization ability.
Zhang
Xin
X
Department of Chemistry, Shantou University, Shantou, China. xzhang@stu.edu.cn
Guan
Ren-Feng
RF
Wu
Dan-Qi
DQ
Chan
Kwong-Yu
KY
D000327:Adsorption; D000588:Amines / Q000138:chemical synthesis / Q000737:chemistry; D000818:Animals; D001672:Biocompatible Materials / Q000138:chemical synthesis* / Q000737:chemistry; D002417:Cattle; D004655:Emulsions; D005949:Glucose Oxidase / Q000737:chemistry; D006863:Hydrogen-Ion Concentration; D066298:In Vitro Techniques; D008422:Materials Testing; D046529:Microscopy, Electron, Transmission; D012710:Serum Albumin, Bovine / Q000737:chemistry; D017550:Spectroscopy, Fourier Transform Infrared; D014961:X-Ray Diffraction
D000588:Amines; D001672:Biocompatible Materials; D004655:Emulsions; D012710:Serum Albumin, Bovine; D005949:Glucose Oxidase