title: [Mechanism study of anti-influenza effects of Radix Isatidis water extract by red blood cells capillary electrophoresis].
abstract: OBJECTIVE
  To research the mechanism of the inhibition effects of BWE on cell attachment of influenza virus by capillary electrophoresis.
  
  
  METHODS
  The morphologic difference of red cells after treating with BWE infected by influenza virus was detected with microscope, capillary electrophoresis and HA.
  
  
  RESULTS
  The pretreatment of the normal cells with BWE inhibited the attachment of influenza to the cells, while no meaningful inhibition was observed when influenza virus was pretreated before being inoculated to cells.
  
  
  CONCLUSIONS
  The results indicate that the inhibition effects of BWE on cell attachment of influenza virus may be an important mechanism of anti-influenza activity of Radix Isatidis Extracts.
authors.affiliation: Institute of Biotechnology, Fuzhou University, Fuzhou 350002, China. zerochen98@163.com
authors.forename: Zhi-Wei
authors.initials: ZW
authors.lastname: Chen
authors.forename: Ling-Wei
authors.initials: LW
authors.lastname: Wu
authors.forename: Shu-Tao
authors.initials: ST
authors.lastname: Liu
authors.forename: Chun-Ping
authors.initials: CP
authors.lastname: Cai
authors.forename: Ping-Fan
authors.initials: PF
authors.lastname: Rao
authors.forename: Li-Jing
authors.initials: LJ
authors.lastname: Ke
mesh_terms: D000998:Antiviral Agents / Q000302:isolation & purification / Q000494:pharmacology*; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification / Q000494:pharmacology*; D019075:Electrophoresis, Capillary; D004912:Erythrocytes / Q000648:ultrastructure* / Q000821:virology; D006385:Hemagglutination Inhibition Tests; D006801:Humans; D009980:Influenza A virus / Q000187:drug effects*; D031219:Isatis / Q000737:chemistry; D008297:Male; D018517:Plant Roots / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry
chemical_list: D000998:Antiviral Agents; D004365:Drugs, Chinese Herbal