[Cerebellar syndromes in Langerhans' cell histiocytosis].
We report a 24-year-old patient with a progressive cerebellar syndrome and history of Langerhans' cell histiocytosis. Neurological symptoms started 5 years after completion of combined radio- and chemotherapy which had led to complete and permanent remission of the primary disease. The clinical and neuroradiological findings obtained mirror progressive neurodegenerative alterations of the cerebellum that represent one of the three classic CNS manifestations of Langerhans' cell histiocytosis.
Bös
M
M
Klinik und Poliklinik für Neurologie und Epileptologie, Universitätsklinikum Bonn, Sigmund-Freud-Strasse 25, 53105 Bonn. monika.boes@ukb.uni-bonn.de
Grothe
C
C
Urbach
H
H
Schröder
R
R
D000328:Adult; D002526:Cerebellar Diseases / Q000175:diagnosis* / Q000628:therapy*; D006646:Histiocytosis, Langerhans-Cell / Q000175:diagnosis* / Q000628:therapy*; D006801:Humans; D008297:Male; D019636:Neurodegenerative Diseases / Q000175:diagnosis* / Q000628:therapy*