[Utility of arterial infusion chemotherapy and radiation therapy for the pelvic local recurrence of rectal cancer].
We treated 3 cases of local pelvic recurrence due to a rectal cancer post operation by arterial infusion chemotherapy with 5-FU and levofolinate calcium and also by radiation therapy. The result of imaging analysis showed that a recurrent tumor was decreased effectively in 2 cases by chemo-radiation therapy. We confirmed the cancer pain and tumor bleeding were gone for all of the 3 cases. As for side effects of arterial infusion chemotherapy and radiation therapy, we confirmed a paralysis of the pelvic nerve in 1 case and dermatopathy in 1 case. This therapy seemed to be an effective treatment for elderly patients with inoperable cases.
Doi
Koichi
K
Dept. of Surgery, Miyazaki Prefectural Nobeoka Hospital.
Ohchi
Tetsufumi
T
Ogata
Ken-ichi
K
Matsuo
Akinobu
A
Kudo
Keisuke
K
Otao
Ryu
R
Muranaka
Takahiro
T
D000368:Aged; D000369:Aged, 80 and over; D003131:Combined Modality Therapy / Q000009:adverse effects; D005472:Fluorouracil / Q000008:administration & dosage; D006801:Humans; D007261:Infusions, Intra-Arterial / Q000009:adverse effects; D002955:Leucovorin / Q000008:administration & dosage; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D010386:Pelvic Neoplasms / Q000188:drug therapy / Q000532:radiotherapy / Q000628:therapy*; D012004:Rectal Neoplasms / Q000601:surgery / Q000628:therapy*
D002955:Leucovorin; D005472:Fluorouracil