title: Cationic surfactant changes the morphology of DNA molecules.
abstract: The effect of cetyltrimethylammonium bromide (CTAB), a cationic surfactant, was investigated on the aggregated form of DNA molecules in water at a given temperature. CTAB caused changes in the aggregated form of DNA molecules from loosely packed spherical to rodlike through toroidal one with increasing concentration below the critical micelle concentration (CMC). The change was suggested to arise from the ion complex formation between CTAB and DNA molecules due to the electrostatic interaction, thereby reducing the surface charge and solubility in water of the latter.
authors.affiliation: Faculty of Science and Technology, Tokyo University of Science, Yamazaki 2641, Noda, Chiba 278-8510, Japan.
authors.forename: Hisanori
authors.initials: H
authors.lastname: Nakanishi
authors.forename: Koji
authors.initials: K
authors.lastname: Tsuchiya
authors.forename: Takahiro
authors.initials: T
authors.lastname: Okubo
authors.forename: Hideki
authors.initials: H
authors.lastname: Sakai
authors.forename: Masahiko
authors.initials: M
authors.lastname: Abe
mesh_terms: D002412:Cations; D000077286:Cetrimonium; D002593:Cetrimonium Compounds / Q000737:chemistry; D002627:Chemistry, Physical / Q000379:methods; D020285:Cryoelectron Microscopy; D004247:DNA / Q000737:chemistry*; D008823:Micelles; D046529:Microscopy, Electron, Transmission; D055672:Static Electricity; D013499:Surface Properties; D013501:Surface-Active Agents / Q000737:chemistry*; D014867:Water / Q000737:chemistry
chemical_list: D002412:Cations; D002593:Cetrimonium Compounds; D008823:Micelles; D013501:Surface-Active Agents; D014867:Water; D004247:DNA; D000077286:Cetrimonium