title: [Spinal anesthesia with low dose sufentanil-bupivacaine in transurethral resection of the prostate].
abstract: OBJECTIVE
  To explore the clinical efficacy of intrathecally administered low dose sufentanil-bupivacaine in transurethral resection of the prostate (TURP). METHODS. Ninety patient (ASA I - III) undergoing TURP were randomly divided into 3 groups (n = 30); Group A, B and C. Group A received 7.5 mg bupivacaine + 5 microg sufentanil + 10% glucose; Group B received 7.5 mg bupivacaine + 7.5 microg sufentanil + 10% glucose; Group C received 15 mg bupivacaine + 10% glucose. The volume was 3 mL in every group. SP, DP, HR, SpO2, the degree of motor and sensory blockade and the side effect were observed.
  
  
  RESULTS
  SP/DP was significantly decreased in Group C than that in Group and Group B (p<0.05), HR and SpO2 in group B were decreased to different degrees 15 min after the injection (p<0.05). The complete recovery time of motor nerve blockade and the regression time of sensory blockade were obviously prolonged in Group C (p<0.05). There were no significant differences in analgesic effect among the three groups during the operation, but the incidence of pruritus was higher in both group A and Group B than that in Group C during the first 24 hours after the injection.
  
  
  CONCLUSIONS
  Spinal anesthesia with low dose sufentanil-bupivacaine possesses relatively steady hemodynamics. The blockade degree of motor and sensory blockade in this spinal anesthesia is lower than that in standard spinal bupivacaine in TURP.
authors.affiliation: Department of Anesthesiology, Xiangya Hospital, Central South University, Changsha 410008, China.
authors.forename: Yi-chun
authors.initials: YC
authors.lastname: Wang
authors.forename: Qu-lian
authors.initials: QL
authors.lastname: Guo
authors.forename: E
authors.initials: E
authors.lastname: Wang
authors.forename: Wang-yuan
authors.initials: WY
authors.lastname: Zou
mesh_terms: D000368:Aged; D000775:Anesthesia, Spinal; D002045:Bupivacaine / Q000008:administration & dosage*; D006801:Humans; D008297:Male; D008875:Middle Aged; D017409:Sufentanil / Q000008:administration & dosage*; D020728:Transurethral Resection of Prostate
chemical_list: D017409:Sufentanil; D002045:Bupivacaine