title: Cytostatic and antibacterial activity of some compounds isolated from several lamiaceae species from the canary islands.
abstract: A chemotherapeutic study has been carried out on thirteen products Eeleven diterpenes, one lignan, (+)-sesamin, and a coumarin, siderin] isolated from SALVIA and SIDERITIS species considered endemic to the Canarian flora. The data obtained suggest that some diterpenoid compounds show an interesting cytostatic activity, specially galdosol ( 6) with an ID (50) value of 0.5 microg/ml. These compounds also evidence a moderate antibacterial activity against Gram positive bacteria.
authors.affiliation: Departamento de Farmacognosia y Farmacodinamia, Facultad de Farmacia, Universidad de La Laguna, Tenerife, Canary Islands, Spain.
authors.forename: V
authors.initials: V
authors.lastname: Darias
authors.forename: L
authors.initials: L
authors.lastname: Bravo
authors.forename: R
authors.initials: R
authors.lastname: Rabanal
authors.forename: C C
authors.initials: CC
authors.lastname: Sánchez-Mateo
authors.forename: D A
authors.initials: DA
authors.lastname: Martín-Herrera