title: Enhancing the regenerative potential of guided tissue regeneration to treat an intrabony defect and adjacent ridge deformity by orthodontic extrusive force.
abstract: BACKGROUND
  The biologic potential of the periodontal ligament (PDL) can be harnessed to solve complex clinical problems involving several dental disciplines. The purpose of this case report is to demonstrate that orthodontic extrusive force can enhance the regenerative potential of guided tissue regeneration (GTR) to eliminate an intrabony defect and augment a ridge deformity.
  
  
  METHODS
  Regenerative therapy by open debridement with particulate anorganic cancellous bovine-derived bone xenograft (BDX), bioabsorbable membrane, and minocycline root conditioning was carried out. Eight weeks after the initial surgery, orthodontic extrusion and uprighting simultaneously were initiated.
  
  
  RESULTS
  Radiographs and reentry documentation demonstrated that orthodontic extrusive force could enhance the regenerative potential of GTR. Consequently, the intrabony defect and alveolar ridge were successfully treated.
  
  
  CONCLUSIONS
  This case report demonstrates that orthodontic-regenerative combined therapy can resolve complex clinical problems involving several dental disciplines.
authors.affiliation: Tokyo, Japan. oshigeki@fantasy.plala.or.jp
authors.forename: Shigeki
authors.initials: S
authors.lastname: Ogihara
authors.forename: Manuel H
authors.initials: MH
authors.lastname: Marks
mesh_terms: D000540:Alveolar Ridge Augmentation / Q000295:instrumentation / Q000379:methods*; D001861:Bone Regeneration / Q000502:physiology; D005260:Female; D048091:Guided Tissue Regeneration / Q000379:methods*; D006801:Humans; D008334:Mandible; D008875:Middle Aged; D008963:Molar / Q000503:physiopathology / Q000601:surgery*; D050793:Orthodontic Extrusion / Q000379:methods*; D009971:Orthodontics, Corrective / Q000379:methods; D010513:Periodontal Ligament / Q000000981:diagnostic imaging / Q000503:physiopathology; D010518:Periodontitis / Q000628:therapy*; D011859:Radiography; D014087:Tooth Movement Techniques / Q000379:methods