Effects of Japanese Torreya (Torreya nucifera) seed oil on the activities and mRNA expression of lipid metabolism-related enzymes in rats.
The mechanism for the plasma and liver triacylglycerol-reducing effects of Japanese torreya (Torreya nucifera) seed oil containing sciadonic acid (all-cis-5, 11, 14-eicosatrienoic acid) is reported. Male SD rats were fed experimental diets containing 10% torreya, corn, or soybean oil for 4 weeks, and the activities and mRNA expression of the enzymes involved in lipid metabolism were measured in the liver. The activities of some hepatic enzymes involved in fatty acid synthesis were lower in the rats fed torreya oil.
Endo
Yasushi
Y
Graduate School of Agricultural Science, Tohoku University, Japan. endo@biochem.tohoku.ac.jp
Osada
Yuko
Y
Kimura
Fumiko
F
Shirakawa
Hitoshi
H
Fujimoto
Kenshiro
K
D000818:Animals; D015870:Gene Expression / Q000187:drug effects*; D050356:Lipid Metabolism / Q000187:drug effects*; D008099:Liver / Q000187:drug effects / Q000201:enzymology; D008297:Male; D010938:Plant Oils / Q000494:pharmacology*; D012333:RNA, Messenger / Q000235:genetics; D051381:Rats; D017207:Rats, Sprague-Dawley; D012639:Seeds / Q000737:chemistry; D032490:Taxaceae / Q000737:chemistry*
D010938:Plant Oils; D012333:RNA, Messenger