[Induction of urothelial carcinoma due to chronic arsenic ingestion? A occupational medicine-toxicological excursion].
Whether chronic intoxication with arsenic can induce cancer of the urinary tract is an important question in urology and occupational medicine. Here, we consider potential exposure, and discuss the epidemiology and toxicology of arsenic. In addition, we conceptualize a possible strategy for clinical procedures.
Müller
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Institut und Poliklinik für Arbeitsmedizin der Universität des Saarlandes und Präventivmedizinisches Zentrum für arbeits- u. umweltbedingte Erkrankungen, Universitätsklinikum, 66421 Homburg/Saar. ammmue@uniklinikum-saarland.de
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D000284:Administration, Oral; D001151:Arsenic / Q000008:administration & dosage / Q000493:pharmacokinetics / Q000633:toxicity*; D020261:Arsenic Poisoning / Q000150:complications* / Q000175:diagnosis / Q000453:epidemiology; D002295:Carcinoma, Transitional Cell / Q000139:chemically induced* / Q000175:diagnosis / Q000453:epidemiology; D003430:Cross-Sectional Studies; D004781:Environmental Exposure / Q000009:adverse effects; D005858:Germany; D006801:Humans; D007680:Kidney Neoplasms / Q000139:chemically induced / Q000175:diagnosis / Q000453:epidemiology; D009784:Occupational Diseases / Q000139:chemically induced* / Q000175:diagnosis / Q000453:epidemiology; D016273:Occupational Exposure / Q000009:adverse effects; D012307:Risk Factors; D001749:Urinary Bladder Neoplasms / Q000139:chemically induced* / Q000175:diagnosis / Q000453:epidemiology; D014874:Water Pollutants, Chemical / Q000633:toxicity
D014874:Water Pollutants, Chemical; D001151:Arsenic