title: Alcohol injection for the intrauterine treatment of chorioangioma in a pregnancy with transfusion resistant fetal anemia: a case report.
abstract: Chorioangiomas are usually small, clinically inevident, benign vascular lesions of the placenta, but larger ones may cause serious perinatal and neonatal complications. There is need for in utero intervention in these fetuses. Several interventions are described to relieve pathophysiologic insult on fetus. Alcohol injection is one of the therapeutic interventions. In this case, we present a patient with chorioangioma and early onset of hydrops fetalis and polyhydramnios at 24th week of gestation. Successful intratumoral injection of absolute ethyl alcohol relieved hydrops fetalis and polyhydramnios. Unfortunately, pregnancy ended at 28th week and a 1,330 g fetus was delivered.
authors.affiliation: Department of Obstetrics and Gynecology, Division of Maternal Fetal Medicine, Hacettepe University, Ankara, Turkey.
authors.forename: Ozgur
authors.initials: O
authors.lastname: Deren
authors.forename: Ozgur
authors.initials: O
authors.lastname: Ozyuncu
authors.forename: Lutfu S
authors.initials: LS
authors.lastname: Onderoglu
authors.forename: Tekin
authors.initials: T
authors.lastname: Durukan
mesh_terms: D000328:Adult; D000740:Anemia / Q000628:therapy*; D001805:Blood Transfusion, Intrauterine; D000431:Ethanol / Q000008:administration & dosage / Q000627:therapeutic use*; D005260:Female; D046128:Fetal Therapies / Q000379:methods*; D006391:Hemangioma / Q000000981:diagnostic imaging / Q000628:therapy*; D006801:Humans; D015160:Hydrops Fetalis / Q000000981:diagnostic imaging / Q000188:drug therapy; D007231:Infant, Newborn; D015552:Injections, Intralesional; D010922:Placenta Diseases / Q000000981:diagnostic imaging / Q000628:therapy*; D006831:Polyhydramnios / Q000000981:diagnostic imaging / Q000188:drug therapy; D011247:Pregnancy; D016216:Ultrasonography, Prenatal
chemical_list: D000431:Ethanol