title: Comparison of virtual colonoscopy with conventional colonoscopy in detection of colorectal polyps.
abstract: OBJECTIVE
  To determine the sensitivity and specificity of multidetector computed tomography-based virtual colonoscopy for colorectal polyp detection by using conventional colonoscopy as the reference standard.
  
  
  METHODS
  48 patients with high risk for colorectal cancer underwent virtual colonoscopy followed by conventional colonoscopy. Examination results were compared with conventional colonoscopy, which served as the gold standard.
  
  
  RESULTS
  Virtual colonoscopy correctly depicted 19 of 22 polyps (sensitivity, 86%) that were detected in conventional colonoscopy. All 4 polyps that were greater than 10 mm in size (100%), 6 of 7 polyps 6-9 mm in size (85%), and 9 of 11 polyps 5 mm in size or smaller (81%) were correctly depicted with virtual colonoscopy. Virtual colonoscopy had an overall sensitivity of 86% and specificity of 98%.
  
  
  CONCLUSIONS
  Multidetector computed tomography-based virtual colonoscopy has excellent sensitivity for the detection of clinically important colorectal polyps.
authors.affiliation: Department of Radiology, Istanbul University, Cerrahpaşa Medical Faculty, Turkey.
authors.forename: Doğan
authors.initials: D
authors.lastname: Selçuk
authors.forename: Kemal
authors.initials: K
authors.lastname: Demirel
authors.forename: Harun
authors.initials: H
authors.lastname: Ozer
authors.forename: Bilgi
authors.initials: B
authors.lastname: Baca
authors.forename: Ibrahim
authors.initials: I
authors.lastname: Hatemi
authors.forename: Ismail
authors.initials: I
authors.lastname: Mihmanli
authors.forename: Uğur
authors.initials: U
authors.lastname: Korman
authors.forename: Gündüz
authors.initials: G
authors.lastname: Oğüt
mesh_terms: D000236:Adenoma / Q000000981:diagnostic imaging* / Q000473:pathology; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002277:Carcinoma / Q000000981:diagnostic imaging* / Q000473:pathology; D003111:Colonic Polyps / Q000000981:diagnostic imaging* / Q000473:pathology; D023881:Colonography, Computed Tomographic; D015179:Colorectal Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests