Investigation of a global collection of nontyphoidal Salmonella of various serotypes cultured between 1953 and 2004 for the presence of class 1 integrons.
In this study, antibiotic resistance profiles, and the presence of class 1 integrons were determined for 108 Salmonella isolates comprising 37 serotypes cultured from a variety of sources between 1953 and 2004. Antibiogram analyses showed that all isolates were resistant to streptomycin/spectinomycin. Molecular analysis revealed that 50% of the collection contained an integrase-encoding gene (int1) and 25% contained class 1 integrons. A Salmonella Wien isolate possessing a complete class 1 integron with a dfrA5-ereA2 gene arrangement within the variable region was characterized.
Murphy
Brenda P
BP
Veterinary Department, Cork County Council, County Hall, Cork, Ireland.
O'Mahony
Rebecca
R
Buckley
James F
JF
Shine
Priscilla
P
Boyd
E Fidelma
EF
Gilroy
Deirdre
D
Fanning
Séamus
S
D000900:Anti-Bacterial Agents / Q000494:pharmacology; D001483:Base Sequence; D004269:DNA, Bacterial / Q000235:genetics; D024901:Drug Resistance, Multiple, Bacterial; D032023:Integrons / Q000235:genetics*; D008826:Microbial Sensitivity Tests; D008957:Models, Genetic; D008969:Molecular Sequence Data; D012475:Salmonella / Q000145:classification / Q000187:drug effects / Q000235:genetics*; D012703:Serotyping; D013307:Streptomycin / Q000494:pharmacology*
D000900:Anti-Bacterial Agents; D004269:DNA, Bacterial; D013307:Streptomycin