The impact of preventive HPV vaccination.
The clearly defined causation by papillomavirus (HPV) and precursor lesions of cervical cancer have made this cancer largely preventable through Pap screening programs, and now by vaccination with Gardasil. This represents an important public health success story and here the authors summarize the potential impact of preventive HPV vaccination and some of the outstanding questions.
Roden
Richard
R
Department of Pathology, The Johns Hopkins University, Baltimore, Maryland 21201, USA. roden@jhmi.edu
Monie
Archana
A
Wu
T C
TC
D002986:Clinical Trials as Topic; D005260:Female; D000068857:Human Papillomavirus Recombinant Vaccine Quadrivalent, Types 6, 11, 16, 18; D006801:Humans; D016867:Immunocompromised Host; D008297:Male; D008958:Models, Molecular; D053918:Papillomavirus Vaccines / Q000627:therapeutic use*; D002583:Uterine Cervical Neoplasms / Q000276:immunology / Q000517:prevention & control* / Q000821:virology; D014611:Vaccination; D014626:Vaginal Smears; D002578:Uterine Cervical Dysplasia / Q000276:immunology / Q000517:prevention & control* / Q000821:virology
D000068857:Human Papillomavirus Recombinant Vaccine Quadrivalent, Types 6, 11, 16, 18; D053918:Papillomavirus Vaccines