Three-component, one-pot synthesis of 2,4,5-substituted pyrimidines library for screening against human hepatocellular carcinoma BEL-7402 cells.
Xie
Fuchun
F
Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zu Chong Zhi Road, Shanghai 201203, China.
Li
Shukun
S
Bai
Donglu
D
Lou
Liguang
L
Hu
Youhong
Y
D000578:Amidines / Q000737:chemistry; D000970:Antineoplastic Agents / Q000138:chemical synthesis* / Q000494:pharmacology*; D001897:Boronic Acids / Q000737:chemistry; D006528:Carcinoma, Hepatocellular / Q000188:drug therapy; D045744:Cell Line, Tumor; D002867:Chromones / Q000737:chemistry; D020650:Combinatorial Chemistry Techniques / Q000379:methods; D004354:Drug Screening Assays, Antitumor; D006801:Humans; D020128:Inhibitory Concentration 50; D008113:Liver Neoplasms / Q000188:drug therapy; D015394:Molecular Structure; D011743:Pyrimidines / Q000138:chemical synthesis* / Q000494:pharmacology*
D000578:Amidines; D000970:Antineoplastic Agents; D001897:Boronic Acids; D002867:Chromones; D011743:Pyrimidines