Asymmetrical alien hands in corticobasal degeneration.
There are several forms of alien limb, but alien limb in corticobasal degeneration (CBD) is not well understood. We studied a patient with CBD who demonstrated two different types of alien limb. With his right hand he demonstrated a tactile avoidance response with levitation. With his left hand, he demonstrated continuous tactile pursuit of the examiner's hand ("tactile mitgehen"). Mitgehen is often associated with frontal dysfunction, but avoidance response and levitation are often associated with parietal dysfunction.
Fitzgerald
David B
DB
Department of Neurology, University of Florida, Gainesville, Florida, USA. dfitzger@massmed.org
Drago
Valeria
V
Jeong
Yong
Y
Chang
Yu-Ling
YL
White
Keith D
KD
Heilman
Kenneth M
KM
D000377:Agnosia / Q000175:diagnosis / Q000453:epidemiology* / Q000503:physiopathology*; D001284:Atrophy / Q000453:epidemiology / Q000473:pathology / Q000503:physiopathology; D001480:Basal Ganglia Diseases / Q000453:epidemiology / Q000473:pathology* / Q000503:physiopathology*; D001921:Brain / Q000378:metabolism / Q000473:pathology / Q000503:physiopathology; D017809:Fatal Outcome; D005625:Frontal Lobe / Q000473:pathology / Q000503:physiopathology; D006225:Hand; D018737:Hand Strength / Q000502:physiology; D006801:Humans; D016631:Lewy Bodies / Q000378:metabolism; D008279:Magnetic Resonance Imaging; D008297:Male; D017628:Microglia / Q000473:pathology; D008875:Middle Aged; D009129:Muscle Tonus / Q000502:physiology; D009410:Nerve Degeneration / Q000453:epidemiology / Q000473:pathology* / Q000503:physiopathology*; D009474:Neurons / Q000378:metabolism / Q000473:pathology; D012720:Severity of Illness Index; D013378:Substantia Nigra / Q000473:pathology; D014110:Touch / Q000502:physiology; D014743:Videotape Recording; D016875:tau Proteins / Q000378:metabolism
D016875:tau Proteins