Neurosarcoidosis presenting as acute infarction on diffusion-weighted MR imaging: summary of radiologic findings.
A 36-year-old woman presented with acute-onset right lower extremity paresthesias, dysarthria, right facial droop, and right hemiparesis. CT and MR imaging of the brain revealed extensive white matter disease and left basal ganglia infarction with dural and leptomeningeal enhancement. Differential considerations included vasculitis, granulomatous disease, and neoplasm. Chest, abdomen, and pelvis CTs were normal. Right temporal lobe biopsy revealed noncaseating granulomatous inflammation consistent with neurosarcoidosis.
Hodge
M H
MH
Department of Radiology, Allegheny General Hospital, Pittsburgh, PA 15212, USA.
Williams
R L
RL
Fukui
M B
MB
D000328:Adult; D001480:Basal Ganglia Diseases / Q000175:diagnosis / Q000209:etiology*; D001706:Biopsy; D001927:Brain Diseases / Q000175:diagnosis*; D002544:Cerebral Infarction / Q000175:diagnosis / Q000209:etiology*; D003937:Diagnosis, Differential; D038524:Diffusion Magnetic Resonance Imaging; D004388:Dura Mater / Q000473:pathology; D004401:Dysarthria / Q000209:etiology; D005158:Facial Paralysis / Q000209:etiology; D005260:Female; D005625:Frontal Lobe / Q000473:pathology; D006429:Hemiplegia / Q000209:etiology; D006801:Humans; D007866:Leg / Q000294:innervation; D008578:Meninges / Q000473:pathology; D009460:Neurologic Examination; D010292:Paresthesia / Q000209:etiology; D012507:Sarcoidosis / Q000175:diagnosis*; D013702:Temporal Lobe / Q000473:pathology