title: Microwave hyperthermia treatment increases heat shock proteins in human skeletal muscle.
abstract: OBJECTIVE
  To test the hypothesis that microwave hyperthermia treatment (MHT) increases heat shock proteins (HSPs) in the human vastus lateralis muscle.
  
  
  METHODS
  Four untrained healthy male volunteers participated in this study. The lateral side of the thigh of one leg (heated leg) was heated with a microwave generator (2.5 GHz, 150 W) for 20 min. At 1 day after the MHT, a muscle sample was taken from the heated leg. A control sample was taken from the unheated leg on another day of the MHT. For both legs, HSP90, HSP72 and HSP27 levels were compared.
  
  
  RESULTS
  The HSP90, HSP72 and HSP27 levels in heated legs were significantly higher than those in control legs (p<0.05).
  
  
  CONCLUSIONS
  Application of MHT can increase the levels of several HSPs in human skeletal muscle.
authors.affiliation: Institute of Health and Sports Science & Medicine, Juntendo University, Hiragagakuendai, Inba, Chiba, Japan. yuji-ogura@sakura.juntendo.ac.jp
authors.forename: Yuji
authors.initials: Y
authors.lastname: Ogura
authors.forename: Hisashi
authors.initials: H
authors.lastname: Naito
authors.forename: Toshihiro
authors.initials: T
authors.lastname: Tsurukawa
authors.forename: Noriko
authors.initials: N
authors.lastname: Ichinoseki-Sekine
authors.forename: Norio
authors.initials: N
authors.lastname: Saga
authors.forename: Takao
authors.initials: T
authors.lastname: Sugiura
authors.forename: Shizuo
authors.initials: S
authors.lastname: Katamoto
mesh_terms: D000328:Adult; D015153:Blotting, Western; D001831:Body Temperature; D006360:Heat-Shock Proteins / Q000378:metabolism*; D006801:Humans; D006979:Hyperthermia, Induced / Q000379:methods*; D007866:Leg; D008297:Male; D008872:Microwaves / Q000627:therapeutic use*; D018482:Muscle, Skeletal / Q000293:injuries / Q000378:metabolism*; D009135:Muscular Diseases / Q000517:prevention & control*
chemical_list: D006360:Heat-Shock Proteins