title: [Influence of different surface machining treatments of resorbable implants made from different magnesium-calcium alloys on their degradation--a pilot study in rabbit models].
abstract: To examine the influence of different surface machining treatments of resorbable implants 3x5 mm cylinders of magnesium-calcium-alloys with plane, rough or sand blasted surface and different concentrations of calcium (0.4 %, 0.8 %, 1.2 % und 2.0 %) were implanted into the distal femur condylus of 18 New Zealand White Rabbits. They were placed into the spongy-cortical passage. During six weeks the animals were examined daily and x-rayed weekly. After euthanasia the bone was explanted and scanned in a microcomputed tomograph. The implants were well tolerated by the rabbits, neither lameness nor signs of pain occured. Wound healing was mostly without complications. Eight of 36 implants (22 %) showed dehiscence of suture within first ten days, whereby implants made of 1,2 % MgCa were mainly affected (six of 12 cases, 50 %). At the place of insertion all implants induced obvious callus genesis which could be seen in MgCa 1,2-cylinders with plane surface and MgCa 0,8-cylinders with rough and sand blasted surface the most. Influence of different calcium concentrations on degradation behaviour could not be discovered. They showed different stages of resorption. Concerning the different surface machining treatments sand blasted implants showed the highest degree of degradation which could be seen by the totally loss of structure in micro-computed examinations. These implants also showed in six of 36 cases a clinical occurrence of gas production. Rough implants showed an irregular degradation with high degree of resorption of some implants and signs of degradation only in the border area of others. Cylindricity maintained in plane implants. They showed loss of structure only in border areas.
authors.affiliation: Klinik für kleine Haustiere, Stiftung Tierärztliche Hochschule Hannover. Nina.von.der.Hoeh@tiho-hannover.de
authors.forename: N
authors.initials: N
authors.lastname: von der Höh
authors.forename: A
authors.initials: A
authors.lastname: Krause
authors.forename: C
authors.initials: C
authors.lastname: Hackenbroich
authors.forename: D
authors.initials: D
authors.lastname: Bormann
authors.forename: A
authors.initials: A
authors.lastname: Lucas
authors.forename: A
authors.initials: A
authors.lastname: Meyer-Lindenberg
mesh_terms: D000497:Alloys; D000818:Animals; D002118:Calcium; D005260:Female; D005269:Femur / Q000000981:diagnostic imaging / Q000601:surgery*; D008274:Magnesium; D008852:Microradiography / Q000662:veterinary; D016348:Osseointegration / Q000502:physiology*; D019736:Prostheses and Implants / Q000592:standards / Q000662:veterinary*; D011817:Rabbits; D013499:Surface Properties
chemical_list: D000497:Alloys; D008274:Magnesium; D002118:Calcium