title: DNA vaccines: recent technological and clinical advances.
abstract: DNA vaccines generate both T cell and B cell (or antibody) mediated immunities. Methods such as prime-boost regimens and the use of adjuvants in combination with the DNA vaccine have enhanced the therapeutic effectiveness of DNA vaccines in the treatment of cancer, infectious diseases, autoimmune diseases, asthma, and other conditions.
authors.affiliation: Novartis Vaccines, Emeryville, CA 94608, USA.
authors.forename: Jeffrey B
authors.initials: JB
authors.lastname: Ulmer
authors.forename: Britta
authors.initials: B
authors.lastname: Wahren
authors.forename: Margaret A
authors.initials: MA
authors.lastname: Liu
mesh_terms: D000276:Adjuvants, Immunologic / Q000008:administration & dosage / Q000627:therapeutic use; D000818:Animals; D001327:Autoimmune Diseases / Q000628:therapy; D006801:Humans; D008954:Models, Biological; D009369:Neoplasms / Q000628:therapy; D019444:Vaccines, DNA / Q000008:administration & dosage / Q000627:therapeutic use*
chemical_list: D000276:Adjuvants, Immunologic; D019444:Vaccines, DNA