title: Non-convulsive status epilepticus and generalised tonic-clonic seizures persisting in old age in a patient with idiopathic generalised epilepsy: a long-term observation.
abstract: Persisting non-convulsive status epilepticus in a man with idiopathic generalised epilepsy is reported. After a first generalised tonic/clonic seizure on awakening one day at the age of 20, the patient experienced rare non-convulsive status epilepticus until the age of 73, when the frequency of the episodes increased, in spite of the initiation of treatment with antiepileptic drugs. No significant cognitive decline was documented when the patient was 83. The existence of such conditions in the context of idiopathic generalised epilepsy shows the problems of syndromic diagnosis and of age dependency of some epileptic phenomena over the course of life with potential bidirectional influences between epileptic manifestations and senile processes.
authors.affiliation: Unit of Sleep Medicine and Epilepsy, Institute of Neurology, IRCCS C. Mondino Foundation, Via Mondino 2, I-27100 Pavia, Italy. elenazambrelli@hotmail.com
authors.forename: E
authors.initials: E
authors.lastname: Zambrelli
authors.forename: M
authors.initials: M
authors.lastname: Terzaghi
authors.forename: E
authors.initials: E
authors.lastname: Sinforiani
authors.forename: R
authors.initials: R
authors.lastname: Manni
mesh_terms: D000369:Aged, 80 and over; D003071:Cognition; D004569:Electroencephalography; D004832:Epilepsy, Absence / Q000175:diagnosis / Q000503:physiopathology; D004829:Epilepsy, Generalized / Q000175:diagnosis / Q000503:physiopathology; D004830:Epilepsy, Tonic-Clonic / Q000175:diagnosis / Q000503:physiopathology*; D006801:Humans; D008297:Male; D013226:Status Epilepticus / Q000175:diagnosis / Q000503:physiopathology*