title: Endoscopic resection of solid intraventricular brain tumors.
abstract: OBJECTIVE
  Endoscopic removal of intraventricular brain tumors is well established for cystic tumors such as colloid cysts. Aspiration followed by removal or ablation of the membranous wall is possible given the constituent features of these tumors. It is generally expected that endoscopic removal of solid brain tumors from the intraventricular compartment would impose additional technical demands. In this paper, the feasibility and safety of endoscopic removal of solid intraventricular brain tumors is evaluated.
  
  
  METHODS
  Eighty-one patients who underwent endoscopic management of an intraventricular brain tumor were identified from a prospective database. Of these patients, seven underwent attempted endoscopic surgical removal of a solid primary brain tumor. Patient selection, surgical technique, procedure-related morbidity, and extent of removal were reviewed. Five patients underwent complete resection of a solid intraventricular brain tumor, a treatment option that was based on intraoperative assessment and confirmed by postoperative imaging. No patient experienced any procedure-related morbidity. Of the individuals in whom a total endoscopic resection was successful, there has been no symptomatic or radiological evidence of recurrence (mean follow up 20 months). Maximum tumor diameter ranged from 0.5 to 1.8 cm for patients who underwent complete resection, whereas maximum tumor diameter measured 2.4 and 2.5 cm in the two patients in whom a subtotal excision was performed.
  
  
  CONCLUSIONS
  In select patients, complete endoscopic removal of solid intraventricular brain tumors is possible and safe. Factors that influence the ability of a surgeon to perform a complete endoscopic resection include tumor size, composition, and vascularity. The procedure requires careful patient selection, the use of refined endoscopic instrumentation, and a disciplined surgical technique.
authors.affiliation: Department of Pediatrics and Neurological Surgery, Weill Medical College of Cornell University, New York, New York 10021, USA. mmsouwei@med.cornell.edu
authors.forename: Mark M
authors.initials: MM
authors.lastname: Souweidane
authors.forename: Neal
authors.initials: N
authors.lastname: Luther
mesh_terms: D000328:Adult; D002551:Cerebral Ventricle Neoplasms / Q000175:diagnosis / Q000601:surgery*; D002552:Cerebral Ventricles / Q000473:pathology / Q000601:surgery; D015331:Cohort Studies; D019723:Endoscopes; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D018365:Neoplasm, Residual / Q000175:diagnosis; D011183:Postoperative Complications / Q000175:diagnosis; D011446:Prospective Studies; D013525:Surgical Instruments; D016896:Treatment Outcome; D014696:Ventriculostomy / Q000295:instrumentation*