title: Giant apocrine hidradenoma of the breast.
abstract: We report a case of a 26-year-old woman with an 8.0-cm tumor of the left breast. The tumor was clinically and radiologically suspicious for malignancy. The pathologic evaluation of the core biopsy and the subsequent excision specimen revealed a benign sclerosing, cystic, and papillary adnexal tumor with apocrine and clear cell morphology. The immunohistochemical staining for p63 was positive. Estrogen, progesterone, and Her-2 receptor immunohistochemical stains were negative. The cytogenetic analysis revealed 46, XX t(11:19) (q21;q13.1) balanced translocation. The final diagnosis was apocrine hidradenoma.
authors.affiliation: Department of Pathology, Medical College of Wisconsin, Miwaukee, Wisconsin 53226, USA. dknoedle@mcw.edu
authors.forename: Darly
authors.initials: D
authors.lastname: Knoedler
authors.forename: Barbara
authors.initials: B
authors.lastname: Susnik
authors.forename: Mary Beth
authors.initials: MB
authors.lastname: Gonyo
authors.forename: Vladimir
authors.initials: V
authors.lastname: Osipov
mesh_terms: D006607:Adenoma, Sweat Gland / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D000328:Adult; D001943:Breast Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D011859:Radiography; D013544:Sweat Gland Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D014463:Ultrasonography