Supported lipid bilayer self-spreading on a nanostructured silicon surface.
We report on the self-spreading behavior of a supported lipid bilayer (SLB) on a silicon surface with various 100 nm nanostructures. SLBs have been successfully grown from a small spot of a lipid molecule source both on a flat surface and uneven surfaces with 100 nm up-and-down nanostructures. After an hour, the self-spreading SLB forms a large circle or an ellipse depending on the nanostructure pattern. The results are explained by a model that shows that a single-layer SLB grows along the nanostructured surfaces. The model is further supported by a quantitative analyses of our data. We also discuss the stability of the SLB on nanostructured surfaces in terms of the balance between its bending and adhesion energies.
Furukawa
Kazuaki
K
NTT Basic Research Laboratories, NTT Corporation, 3-1 Morinosato Wakamiya, Atsugi, Kanagawa, Japan 243-0198. furukawa@ nttbrl.jp
Sumitomo
Koji
K
Nakashima
Hiroshi
H
Kashimura
Yoshiaki
Y
Torimitsu
Keiichi
K
D000818:Animals; D002627:Chemistry, Physical / Q000379:methods; D004530:Egg Yolk / Q000378:metabolism; D008051:Lipid Bilayers / Q000737:chemistry*; D008567:Membranes, Artificial; D008855:Microscopy, Electron, Scanning; D049329:Nanostructures / Q000737:chemistry*; D036103:Nanotechnology / Q000379:methods*; D010713:Phosphatidylcholines / Q000737:chemistry; D010718:Phosphatidylserines / Q000737:chemistry; D010743:Phospholipids / Q000737:chemistry; D012825:Silicon / Q000737:chemistry*; D013499:Surface Properties; D013997:Time Factors; D000267:Tissue Adhesions
D008051:Lipid Bilayers; D008567:Membranes, Artificial; D010713:Phosphatidylcholines; D010718:Phosphatidylserines; D010743:Phospholipids; D012825:Silicon