Celiprolol-induced lupus-like syndrome.
Systemic lupus erythematosus can be idiopathic or drug-induced. Although a number of beta-blockers have been reported to induce a lupus-like syndrome, to the best of our knowledge, no such case has been described following celiprolol therapy. We diagnosed a lupus-like syndrome in a 67-year-old female patient who developed febrile polyarthritis, percarditis, antinuclear and anti-histone antibodies after taking celiprolol for 2 years. Despite drug withdrawal, prolonged corticotherapy was needed to obtain clinical and biological remission.
Charniot
Jean-Christophe
JC
Department of Cardiology, Avicenne Hospital, Bobigny, France. jean-christophe.charniot@avc.ap-hop-paris.fr
Genereau
Thierry
T
Mouthon
Luc
L
D000368:Aged; D017272:Celiprolol / Q000009:adverse effects* / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000097:blood / Q000139:chemically induced* / Q000175:diagnosis
D017272:Celiprolol