title: Treatment of mycosis fungoides: overview.
abstract: BACKGROUND
  Mycosis fungoides (MF) is the most common clinicopathologic subtype of primary cutaneous T-cell lymphoma.
  
  
  OBJECTIVE
  The therapy of MF is highlighted in this overview.
  
  
  CONCLUSIONS
  Skin-directed MF therapies include topical corticosteroids, nitrogen mustard, carmustine (BCNU), topical bexarotene gel, imiquimod cream, radiotherapy, total skin electron beam therapy, and phototherapy. Systemic therapies include extracorporeal photopheresis, interferon, oral bexarotene, denileukin diftitox, monoclonal antibodies and cytokine therapy, and other systemic chemotherapy. Finally, some investigative therapeutic modalities are presented.
authors.affiliation: Division of Dermatology, University of Toronto, ON. Canada. anatoli.freiman@sympatico.ca
authors.forename: Anatoli
authors.initials: A
authors.lastname: Freiman
authors.forename: Denis
authors.initials: D
authors.lastname: Sasseville
mesh_terms: D003131:Combined Modality Therapy; D006801:Humans; D009182:Mycosis Fungoides / Q000628:therapy*; D012878:Skin Neoplasms / Q000628:therapy*