title: Single breath vital capacity induction of anesthesia with 8% sevoflurane versus intravenous propofol for laryngeal tube insertion in adults.
abstract: OBJECTIVE
  To compare the conditions for laryngeal tube airway insertion obtained by the inhalation of 8% sevoflurane using a vital capacity breath (VCB) technique with propofol intravenous induction.
  
  
  METHODS
  We carried out a prospective, randomized, single blind study at King Abdullah University Hospital, Irbid, Jordan from September 2005 to April 2006. Involved in this study were 80 adult (ASA physical status I and II) patients aged 26-70 years undergoing elective surgery under general anesthesia. The patients were randomized into 2 groups. An independent observer noted the time to loss of consciousness, the presence of adverse events, time to successful laryngeal tube placement and the number of attempts needed until a successful laryngeal tube insertion.
  
  
  RESULTS
  With the single VCB method, sevoflurane produced a loss of consciousness faster than propofol did (51.6 +/- 4.4 versus 59.7 +/- 4.9 seconds, p<0.001). The insertion of laryngeal tube was faster in the propofol group (77.2 +/- 20.2 versus 122.2 +/- 33.3 seconds, p<0.001) and required fewer attempts (1.2 +/- 0.4 versus 1.6 +/- 0.7, p<0.02). The overall incidence of complications during the induction of anesthesia as well as during the laryngeal tube insertion, especially apnea (42% versus 0%; p<0.001), was more frequent in the propofol group (82.5% versus 27.5%; p<0.001).
  
  
  CONCLUSIONS
  We conclude that vital capacity breath induction with sevoflurane produces a faster loss of consciousness and fewer side effects than propofol and efficient for laryngeal tube insertion, but takes slightly longer than propofol due to the prolonged jaw tightness.
authors.affiliation: Department of Anesthesia, King Abdullah University Hospital, Faculty of Medicine, Jordan University of Science and Technology, PO Box 953, Irbid 21110, Jordan. elradk01@yahoo.com
authors.forename: Khaled M
authors.initials: KM
authors.lastname: El-Radaideh
authors.forename: Mohammed A
authors.initials: MA
authors.lastname: Al-Ghazo
mesh_terms: D000328:Adult; D000368:Aged; D000758:Anesthesia / Q000379:methods*; D018685:Anesthetics, Inhalation / Q000008:administration & dosage*; D018686:Anesthetics, Intravenous / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D007440:Intubation / Q000379:methods*; D007830:Larynx; D008297:Male; D008738:Methyl Ethers / Q000008:administration & dosage*; D008875:Middle Aged; D015742:Propofol / Q000008:administration & dosage*; D012119:Respiration; D000077149:Sevoflurane; D016037:Single-Blind Method; D014797:Vital Capacity
chemical_list: D018685:Anesthetics, Inhalation; D018686:Anesthetics, Intravenous; D008738:Methyl Ethers; D000077149:Sevoflurane; D015742:Propofol