title: Synthesis of the isonicotinoylnicotinamide scaffolds of the naturally occurring isoniazid-NAD(P) adducts.
abstract: The first syntheses of the 1-hydroxy-1-(pyridin-4-yl)-1,2-dihydro-3H-pyrrolo[3,4-c]pyridin-3-one heterocycle and the 3-aminocarbonyl-4-isonicotinoyl-1,4-dihydropyridine framework present in the isoniazid-NAD(P) adducts are described.
authors.affiliation: Laboratoire de Chimie de Coordination du CNRS, 205 route de Narbonne, 31077 Toulouse cedex 4, France.
authors.forename: Tamara
authors.initials: T
authors.lastname: Delaine
authors.forename: Vania
authors.initials: V
authors.lastname: Bernardes-Génisson
authors.forename: Bernard
authors.initials: B
authors.lastname: Meunier
authors.forename: Jean
authors.initials: J
authors.lastname: Bernadou
mesh_terms: D007538:Isoniazid / Q000737:chemistry*; D015394:Molecular Structure; D009249:NADP / Q000737:chemistry*
chemical_list: D009249:NADP; D007538:Isoniazid