Facial Sweet's syndrome mimicking rosacea fulminans.
A 36-year-old man presented with a non-pruritic, erythematous facial rash with peri-oral and peri-orbital sparing. The initial clinicopathological diagnosis was rosacea fulminans, which was treated with 25 mg oral prednisolone and cephalexin. The patient re-presented 1 week later with exacerbation of his rash in addition to constitutional symptoms of fever and malaise. A further skin biopsy was taken and the marked neutrophilic infiltrate in the absence of vasculitis made the diagnosis of Sweet's syndrome (acute febrile neutrophilic dermatosis). High-dose prednisolone (50 mg daily), topical hydrocortisone cream and ichthammol in zinc ointment were commenced with rapid clinical improvement. This case highlights the importance of considering Sweet's syndrome as a differential diagnosis when presented with a facial eruption.
Anavekar
Namrata S
NS
Department of Dermatology, St Vincent's Hospital, Melbourne, Victoria, Australia.
Williams
Richard
R
Chong
Alvin H
AH
D000279:Administration, Cutaneous; D000284:Administration, Oral; D000328:Adult; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage / Q000627:therapeutic use; D003937:Diagnosis, Differential; D005148:Facial Dermatoses / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D006801:Humans; D006854:Hydrocortisone / Q000008:administration & dosage / Q000627:therapeutic use; D008297:Male; D011239:Prednisolone / Q000008:administration & dosage / Q000627:therapeutic use; D012393:Rosacea / Q000175:diagnosis; D016463:Sweet Syndrome / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology
D000893:Anti-Inflammatory Agents; D011239:Prednisolone; D006854:Hydrocortisone