title: Diastereocontrolled synthesis of enantioenriched 3,4-disubstituted beta-prolines.
abstract: Enantioenriched 3,4-disubstituted beta-prolines have been prepared with a high diastereocontrol through a carbometalation reaction or through a domino Michael addition/carbometalation reaction.
authors.affiliation: Laboratoire de Chimie Organique, UMR 7611, FR2769, Université Pierre et Marie Curie, Tour 44-45, 2ème étage, Case 183, 4 place Jussieu, 75252 Paris Cedex 05, France.
authors.forename: Fabrice
authors.initials: F
authors.lastname: Denes
authors.forename: Alejandro
authors.initials: A
authors.lastname: Perez-Luna
authors.forename: Fabrice
authors.initials: F
authors.lastname: Chemla
mesh_terms: D003500:Cyclization; D008968:Molecular Conformation; D011392:Proline / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D011392:Proline; C072401:beta-proline