Ovarian hyperstimulation syndrome caused by pituitary gonadotroph adenoma secreting follicle-stimulating hormone.
BACKGROUND
We report a highly exceptional case in which a gonadotroph adenoma was diagnosed in a patient with normal follicle-stimulating hormone (FSH) levels.


METHODS
A 30-year-old woman with a gonadotroph adenoma presented with hyperstimulation syndrome and normal FSH levels. After treatment of her adenoma she had regular menstrual cycles and subsequently conceived.


CONCLUSIONS
Ovarian hyperstimulation caused by a gonadotroph adenoma in a premenopausal woman with normal FSH levels is extremely rare. However, we propose that gonadotroph adenomas be considered in the differential diagnosis of patients who have this constellation of abnormalities.
Ghayuri
Mohammadreza
M
Department of Obstetrics and Gynecology, MacDonald Women's Hospital, Case Western Reserve University, Cleveland, Ohio, USA. mghayuri@yahoo.com
Liu
James H
JH
D000236:Adenoma / Q000097:blood / Q000150:complications / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D000328:Adult; D003937:Diagnosis, Differential; D005260:Female; D005298:Fertility; D005640:Follicle Stimulating Hormone / Q000097:blood / Q000378:metabolism*; D006065:Gonadotropins, Pituitary / Q000097:blood / Q000378:metabolism*; D006801:Humans; D008279:Magnetic Resonance Imaging; D016471:Ovarian Hyperstimulation Syndrome / Q000097:blood / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000209:etiology; D010911:Pituitary Neoplasms / Q000097:blood / Q000150:complications / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D011247:Pregnancy; D014463:Ultrasonography
D006065:Gonadotropins, Pituitary; D005640:Follicle Stimulating Hormone