13C NMR spectroscopy of some third-generation cephalosporins, their synthetic intermediaries and reaction byproducts.
(13)C NMR spectroscopic data for 25 cephalosporin derivatives were assigned by combination of one- and two-dimensional experiments. The effect of the substitution at C-3, C-7 and C-4 acid group positions on the chemical shifts of the cephem nucleus is discussed.
López
Miguel A
MA
Centro de Química Farmacéutica, Avenida 200 y 21, Siboney, Playa, CP 16042, Ciudad de La Habana, Cuba.
Rodríguez
Zalua
Z
González
Maritza
M
Tolón
Blanca
B
Avila
Rizette
R
Rodríguez
Juan C
JC
Vélez-Castro
Hermán
H
Fini
Adamo
A
D002247:Carbon Isotopes; D002511:Cephalosporins / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy / Q000379:methods* / Q000592:standards; D015394:Molecular Structure; D012015:Reference Standards; D012680:Sensitivity and Specificity
D002247:Carbon Isotopes; D002511:Cephalosporins