title: [Mediastinal sarcoidal reaction in follow up for seminoma].
abstract: Mediastinal sarcoidal reaction in follow up for seminoma. Testicular germ cell tumors constitute a model for curable neoplasia. Long-term complications are well-known and follow-up includes not only awareness of relapse, but also of the development of secondary tumors and treatment sequelae. In the last two decades, an increase in sarcoidosis incidence has been described in cured patients, who at follow-up present lung nodules or mediastinal lymph nodes. A 28 year-old patient who, on clinical follow up of a semi-nomatous tumor, presented mediastinal lymph nodes on CT scan and chest x-ray, without evidence of disease in pelvis or abdomen is presented. His other testicle was normal and he had negative tumor markers. Because of this rare presentation, a mediastinoscopy was performed and sarcoidosis like reaction was diagnosed. During follow-up of patients with testicular germ cell tumors, the presence of mediastinal lymph nodes requires a histological diagnosis and sarcoidosis should be considered as differential diagnosis.
authors.affiliation: Servicio de Oncología, Hospital Carlos G. Durand, Buenos Aires, Argentina. violejanki@gmail.com
authors.forename: Gustavo
authors.initials: G
authors.lastname: Jankilevich
authors.forename: Javier
authors.initials: J
authors.lastname: Mendizabal
authors.forename: Miguel A
authors.initials: MA
authors.lastname: Massa
authors.forename: Analia
authors.initials: A
authors.lastname: Pedernera
authors.forename: Miguel
authors.initials: M
authors.lastname: Galmes
authors.forename: Nestor
authors.initials: N
authors.lastname: Spizzamiglio
mesh_terms: D000328:Adult; D014408:Biomarkers, Tumor / Q000032:analysis; D003937:Diagnosis, Differential; D005500:Follow-Up Studies; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology; D008207:Lymphatic Metastasis / Q000473:pathology; D008297:Male; D008477:Mediastinal Diseases / Q000209:etiology* / Q000473:pathology; D008482:Mediastinum / Q000473:pathology; D009364:Neoplasm Recurrence, Local / Q000473:pathology / Q000628:therapy; D011379:Prognosis; D012507:Sarcoidosis / Q000209:etiology* / Q000473:pathology; D018239:Seminoma / Q000150:complications* / Q000473:pathology / Q000628:therapy; D013736:Testicular Neoplasms / Q000150:complications* / Q000473:pathology / Q000628:therapy
chemical_list: D014408:Biomarkers, Tumor