Discovery of chemical reactions through multidimensional screening.
Multidimensional reaction screening of ortho-alkynyl benzaldehydes with a variety of catalysts and reaction partners was conducted in an effort to identify new chemical reactions. Reactions affording unique products were selected for investigation of preliminary scope and limitations.
Beeler
Aaron B
AB
Department of Chemistry and Center for Chemical Methodology and Library Development (CMLD-BU), Boston University, 590 Commonwealth Avenue, Boston, Massachusetts 02215, USA.
Su
Shun
S
Singleton
Chris A
CA
Porco
John A
JA
D000480:Alkynes / Q000737:chemistry*; D001547:Benzaldehydes / Q000737:chemistry*; D001688:Biological Products / Q000737:chemistry; D002384:Catalysis; D020650:Combinatorial Chemistry Techniques; D004353:Drug Evaluation, Preclinical / Q000379:methods*; D008024:Ligands; D008956:Models, Chemical; D010636:Phenols / Q000737:chemistry
D000480:Alkynes; D001547:Benzaldehydes; D001688:Biological Products; D008024:Ligands; D010636:Phenols