title: Anatomy of the Boerhaave syndrome.
abstract: BACKGROUND
  Spontaneous rupture of the esophagus (Boerhaave syndrome) occurs almost invariably at the same anatomic site. A weakness of the distal esophageal wall is suspected but has not been confirmed by anatomic studies. The aim of this work was to determine the existence of a structural abnormality in the esophageal wall.
  
  
  METHODS
  In six fresh human cadavers, the left lung was removed and the esophagus was insufflated in situ with air until it burst. The mucosa of the specimens was stripped off, allowing the fibers of the inner muscular coat to be seen. In addition a specimen from a patient who died from this cause was submitted to the same procedure.
  
  
  RESULTS
  The site of the experimental rupture matched the clinical case. The tear was located at the margin of contact between "clasp" and oblique fibers, and extends upwards.
  
  
  CONCLUSIONS
  The connective tissue of the junction between clasp and oblique fibers appears to constitute a weak point in the lower esophagus.
authors.affiliation: Department of Surgery, Clinical Hospital University of Chile, Santiago, Chile. okorn@redclinicauchile.cl
authors.forename: Owen
authors.initials: O
authors.lastname: Korn
authors.forename: Juan C
authors.initials: JC
authors.lastname: Oñate
authors.forename: René
authors.initials: R
authors.lastname: López
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D004935:Esophageal Diseases / Q000473:pathology*; D004947:Esophagus / Q000473:pathology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012422:Rupture, Spontaneous / Q000473:pathology; D013577:Syndrome