title: [Changes in the clinical and anatomo-pathological presentation of prostate cancer in Oviedo in the last 10 years (part I)].
abstract: OBJECTIVE
  To describe the clinical and pathological factors of prostate adenocarcinomas diagnosed in our department in the years 1995 and 2004.
  
  
  METHODS
  We review the 216 patients diagnosed in both years, recording several features.
  
  
  RESULTS
  The mean age was significatively lower in the year 2004. In that year, the increments of the PSA levels was the main reason for the diagnosis of the prostate cancer, followed by low urinary tract symptons (LUTS), while the LUTS was the main reason in 1995. There was a greater proportion of high grade tumors in 1995 and also in this year, high risk tumors were the most frequently found, while in 2004 low risk and low grade tumors were predominant.
  
  
  CONCLUSIONS
  Due to the general determinations of PSA levels in asymptomatic patients in 2004, we found a greater proportion of high grade tumors in 1995 and lower grade tumors in 2004.
authors.affiliation: Servicio de Urología, Hospital Universitario Central de Asturias, Oviedo. malvarez79@mixmail.com
authors.forename: M
authors.initials: M
authors.lastname: Alvarez-Múgica
authors.forename: J M
authors.initials: JM
authors.lastname: Fernández Gómez
authors.forename: S
authors.initials: S
authors.lastname: Escaf Barmadah
authors.forename: A
authors.initials: A
authors.lastname: Jalón Monzón
authors.forename: R C
authors.initials: RC
authors.lastname: González Alvarez
authors.forename: F J
authors.initials: FJ
authors.lastname: Regadera Sejas
mesh_terms: D000230:Adenocarcinoma / Q000097:blood / Q000175:diagnosis*; D000368:Aged; D000369:Aged, 80 and over; D006801:Humans; D008297:Male; D008875:Middle Aged; D017430:Prostate-Specific Antigen / Q000097:blood; D011471:Prostatic Neoplasms / Q000097:blood / Q000175:diagnosis*; D012189:Retrospective Studies; D013030:Spain
chemical_list: D017430:Prostate-Specific Antigen