A "hidden" co-crystal of caffeine and adipic acid.
Co-crystal formation between caffeine and adipic acid has been explored over the years without success; utilizing the newly developed co-crystal screening method, we have finally discovered this "hidden" caffeine and adipic acid co-crystal.
Bucar
Dejan-Kresimir
DK
Solid State Sciences, Global Pharmaceutical R&D, Abbott Laboratories, North Chicago, IL 60064, USA.
Henry
Rodger F
RF
Lou
Xiaochun
X
Borchardt
Thomas B
TB
Zhang
Geoff G Z
GG
D000272:Adipates / Q000737:chemistry*; D002110:Caffeine / Q000737:chemistry*; D003460:Crystallization; D014961:X-Ray Diffraction
D000272:Adipates; D002110:Caffeine; C029900:adipic acid