title: Perioperative morbidity using transvaginal mesh in pelvic organ prolapse repair.
abstract: OBJECTIVE
  To describe the perioperative morbidity associated with transvaginal mesh repair of pelvic organ prolapse.
  
  
  METHODS
  During a 6-month time period, 25 centers registered all surgical procedures using a commercially available mesh. The frequency and type of perioperative complications, during surgery and the associated hospital stay, were documented using a standardized protocol.
  
  
  RESULTS
  During the inclusion period, 248 women underwent transvaginal mesh surgery: anterior repair in 106 patients (43%), posterior repair in 71 (29%), combined anterior and posterior repair in 20 (8%), and total repair in 51 (21%). Mean age was 67.8 years (+/-10.3 standard deviation) and median parity was 2 (range 0-6). Surgery for prolapse recurrence was performed in 56% of the patients (n=140), and 91% (n=225) had undergone at least one previous pelvic floor surgical procedure. Serious complications occurred in 4.4% of patients (n=11) and were dominated by visceral injury (10 of 11 cases). One case of bleeding in excess of 1,000 mL occurred. Minor complications occurred in 14.5% of patients (n=36), and the majority were urinary tract infections, urinary retention, and postoperative fever. A multivariable risk analysis showed that concurrent pelvic floor surgery was associated with an increased risk for minor complications, odds ratio 2.8 (95% confidence interval 1.1-6.9). There were no other predictors of outcomes when assessing the association with age, parity, weight, previous pelvic floor surgery, previous hysterectomy, or concurrent hysterectomy.
  
  
  CONCLUSIONS
  Perioperative serious complications are uncommon after transvaginal mesh procedures although particular care should be taken to detect visceral injury at the time of surgery.
  
  
  METHODS
  III.
authors.affiliation: Division of Obstetrics and Gynecology, Karolinska Institutet Danderyd Hospital, 182 88 Stockholm, Sweden. daniel.altman@ds.se
authors.forename: Daniel
authors.initials: D
authors.lastname: Altman
authors.forename: Christian
authors.initials: C
authors.lastname: Falconer
mesh_terms: D000368:Aged; D005260:Female; D006801:Humans; D007431:Intraoperative Complications; D007902:Length of Stay; D008875:Middle Aged; D011183:Postoperative Complications; D012307:Risk Factors; D013526:Surgical Mesh / Q000009:adverse effects*; D016896:Treatment Outcome; D014596:Uterine Prolapse / Q000601:surgery*; D014621:Vagina / Q000601:surgery*