title: Synthesis of 2(1H)-pyrazinone phosphonates via an Arbuzov-type reaction.
abstract: A simple and catalyst-free method for the synthesis of phosphonated 2(1H)-pyrazinones is described starting from 3,5-dichloropyrazinones. The method also works for 3-bromo- and 3-iodopyrazinones. Classical heating conditions as well as microwave-enhanced reaction conditions were tested.
authors.affiliation: Molecular Design & Synthesis, Department of Chemistry, Katholieke Universiteit Leuven, Celestijnenlaan 200F, B-3001 Leuven, Belgium.
authors.forename: Jo
authors.initials: J
authors.lastname: Alen
authors.forename: Liliana
authors.initials: L
authors.lastname: Dobrzańska
authors.forename: Wim M
authors.initials: WM
authors.lastname: De Borggraeve
authors.forename: Frans
authors.initials: F
authors.lastname: Compernolle