title: General and direct synthesis of 3-aminoindolizines and their analogues via Pd/Cu-catalyzed sequential cross-coupling/cycloisomerization reactions.
abstract: [reaction: see text] An efficient and one-step synthesis of 3-aminoindolizines or benz[e]indolizines from the reactions of propargyl amines or amides with heteroaryl bromides was developed. This methodology is realized by a tandem reaction using Pd/Cu catalysts, which could catalyze coupling and cycloisomerization reactions in the same vessel.
authors.affiliation: State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 354 Fenglin Lu, Shanghai 200032, People's Republic of China. yhliu@mail.sioc.ac.cn
authors.forename: Yuanhong
authors.initials: Y
authors.lastname: Liu
authors.forename: Zhiquan
authors.initials: Z
authors.lastname: Song
authors.forename: Bin
authors.initials: B
authors.lastname: Yan