title: Spondylolisthesis caused by extreme pedicle elongation in osteogenesis imperfecta.
abstract: Although osteogenesis imperfecta is a well-known skeletal disorder, reports of spondylolisthesis in osteogenesis imperfecta are rare. Only very few cases of spondylolisthesis caused by elongation of lumbar pedicles have been described in the literature. Here we report three patients suffering from osteogenesis imperfecta showing a severe form of hyperlordosis caused by lumbar pedicle elongation and consecutive spondylolisthesis. Radiographs in the course of childhood and adolescence show a rapid progression of pedicle elongation and hyperlordosis with increased mechanical loads. The treatment strategy consists of physiotherapy, medical treatment with bisphosphonates, and orthopedic surgery and is preferably conservative. In the three patients reported here, one patient was treated with laminectomy and postero-lateral fusion, whereas in the other two patients surgery is currently not considered as necessary.
authors.affiliation: Department of Orthopaedic Surgery, University of Cologne, Joseph-Stelzmann-Strasse 9, 50924, Köln, Germany. Roland.Ivo@gmx.de
authors.forename: Roland
authors.initials: R
authors.lastname: Ivo
authors.forename: Sebastian
authors.initials: S
authors.lastname: Fuerderer
authors.forename: Peer
authors.initials: P
authors.lastname: Eysel
mesh_terms: D000293:Adolescent; D000328:Adult; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008141:Lordosis / Q000150:complications / Q000000981:diagnostic imaging; D008159:Lumbar Vertebrae / Q000000981:diagnostic imaging / Q000473:pathology*; D008297:Male; D010013:Osteogenesis Imperfecta / Q000150:complications* / Q000000981:diagnostic imaging; D011859:Radiography; D013168:Spondylolisthesis / Q000150:complications* / Q000000981:diagnostic imaging