title: Highly regio- and stereoselective synthesis of indene derivatives via electrophilic cyclization.
abstract: [reaction: see text] Indene or naphthalene derivatives are readily prepared in moderate to excellent yields with high regio- and stereoselectivity under very mild reaction conditions by the reaction of acetylenic malonates and ketones with I2, ICl, or NIS. The resulting iodides can be further elaborated using palladium-catalyzed coupling reactions.
authors.affiliation: State Key Laboratory of Applied Organic Chemistry, Lanzhou University, and State Key Laboratory of Solid Lubrication, Lanzhou Institute of Chemical Physics, Chinese Academy of Science, Lanzhou 730000, P.R. China.
authors.forename: Hai-Peng
authors.initials: HP
authors.lastname: Bi
authors.forename: Li-Na
authors.initials: LN
authors.lastname: Guo
authors.forename: Xin-Hua
authors.initials: XH
authors.lastname: Duan
authors.forename: Fa-Rong
authors.initials: FR
authors.lastname: Gou
authors.forename: Shu-Hao
authors.initials: SH
authors.lastname: Huang
authors.forename: Xue-Yuan
authors.initials: XY
authors.lastname: Liu
authors.forename: Yong-Min
authors.initials: YM
authors.lastname: Liang