title: [The peculiarities of serum levels of S100b protein and antibodies to it in patients with crisis and stable essential hypertension].
abstract: The article covers the results of research into the levels of S100b protein and antibodies to it in the serum of patients with crisis and stable essential hypertension. The results show that neutrophic protein dysmetabolism plays an important role in the pathogenesis of hypertonic dyscirculatory encephalopathy and the forming of cognitive disorder syndrome. The data obtained suggest that hypertensive crises lead to pathologic changes in hematoencephalic barrier permeability and the development of autoimmune reactions with participation of neutrophic proteins.
authors.forename: E A
authors.initials: EA
authors.lastname: Shirokov
authors.forename: M A
authors.initials: MA
authors.lastname: Gruden'
authors.forename: I S
authors.initials: IS
authors.lastname: Denishchuk
authors.forename: E I
authors.initials: EI
authors.lastname: Elistratova
authors.forename: V V
authors.initials: VV
authors.lastname: Iurasov
authors.forename: N K
authors.initials: NK
authors.lastname: Iakovleva
authors.forename: A N
authors.initials: AN
authors.lastname: Shalavin
authors.forename: V V
authors.initials: VV
authors.lastname: Sherstnev
mesh_terms: D000368:Aged; D015415:Biomarkers / Q000097:blood; D001794:Blood Pressure / Q000502:physiology; D001812:Blood-Brain Barrier / Q000378:metabolism; D005260:Female; D006801:Humans; D006973:Hypertension / Q000097:blood* / Q000150:complications / Q000503:physiopathology; D020343:Hypertensive Encephalopathy / Q000097:blood / Q000209:etiology; D008297:Male; D008875:Middle Aged; D009414:Nerve Growth Factors / Q000097:blood*; D064568:S100 Calcium Binding Protein beta Subunit; D009418:S100 Proteins / Q000097:blood*; D012720:Severity of Illness Index
chemical_list: D015415:Biomarkers; D009414:Nerve Growth Factors; D064568:S100 Calcium Binding Protein beta Subunit; D009418:S100 Proteins; C579160:S100B protein, human