title: Quantification of human bocavirus in lower respiratory tract infections in China.
abstract: A quantitative PCR method was established to quantify human bocavirus (HBoV) genomic copies in clinical specimens from children with lower respiratory tract infections (LRTI) in China. A total of 257 respiratory tract specimens were tested, and 7 (2.7%) of these (all sputum samples) were positive, with genomic copies that ranged from 8.0 x 10(3) to 8.0 x 10(9) in the samples. The main clinical symptom of patients who were positive for HBoV DNA was a pneumonia-like syndrome represented by high fever and cough. Our results suggest that HBoV may be an important etiological agent of LRTI in children in China.
authors.affiliation: Wenling First Hospital, Wenling, Zhejiang Province, China. linfengwyy@vip.sina.com
authors.forename: Feng
authors.initials: F
authors.lastname: Lin
authors.forename: Aiping
authors.initials: A
authors.lastname: Zeng
authors.forename: Ningmin
authors.initials: N
authors.lastname: Yang
authors.forename: Haiyan
authors.initials: H
authors.lastname: Lin
authors.forename: En
authors.initials: E
authors.lastname: Yang
authors.forename: Shengqi
authors.initials: S
authors.lastname: Wang
authors.forename: David
authors.initials: D
authors.lastname: Pintel
authors.forename: Jianming
authors.initials: J
authors.lastname: Qiu