title: The prevalence of ocular involvement in patients with inflammatory bowel disease.
abstract: OBJECTIVE
  The aim of this prospective randomized clinical study was to evaluate the prevalence of ocular involvement in patients with inflammatory bowel disease (IBD).
  
  
  METHODS
  We prospectively evaluated 116 patients who went to the gastroenterology clinic with endoscopically proven IBD between December 2001 and February 2005. All patients were examined for evidence of ocular manifestations of IBD. Twenty patients had Crohn's disease and 96 had ulcerative colitis. The examination consisted of slit-lamp examinations, tonometry, visual acuity, and indirect ophthalmoscopy.
  
  
  RESULTS
  The mean age of the 116 patients with IBD who were enrolled was 40.6 +/- 14.4 years (range 16 to 75). Twelve of 20 patients (60%) with Crohn's disease and 22 of 96 patients (22.92%) with ulcerative colitis had ocular involvement. The most common ocular findings were conjunctivitis (8.62%) and blepharitis (6.9%) followed by uveitis (5.17%), cataract (5.17%), and episcleritis (3.45%). Extraintestinal complications were seen in 12 (35.3%) of 34 patients with ocular involvement and in 16 (19.5%) of 82 patients without ocular involvement.
  
  
  CONCLUSIONS
  Because the ocular complaints of IBD patients are often nonspecific, it may be helpful to performed eye examinations as a routine component in the follow-up of these patients. It is well-known that early diagnosis and treatment of ocular involvement may prevent serious ocular complications that could be associated with significant visual morbidity. In addition, clinicians should be aware that some ocular diseases, such as uveitis and scleritis, might precede a diagnosis of ulcerative colitis or Crohn's disease.
authors.affiliation: Department of the Ophthalmology, Izmir Atatürk Training and Research Hospital, Mustafa Kemal Cad. No. 36/4, Izmir, Bornova 35040, Turkey. safiyekucukbay@hotmail.com
authors.forename: Safiye
authors.initials: S
authors.lastname: Yilmaz
authors.forename: Ebru
authors.initials: E
authors.lastname: Aydemir
authors.forename: Ahmet
authors.initials: A
authors.lastname: Maden
authors.forename: Belkis
authors.initials: B
authors.lastname: Unsal
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D003093:Colitis, Ulcerative / Q000175:diagnosis / Q000453:epidemiology; D003424:Crohn Disease / Q000175:diagnosis / Q000453:epidemiology; D005128:Eye Diseases / Q000150:complications* / Q000175:diagnosis* / Q000453:epidemiology; D005260:Female; D006801:Humans; D015212:Inflammatory Bowel Diseases / Q000150:complications* / Q000175:diagnosis / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D011446:Prospective Studies; D015423:Scleritis / Q000175:diagnosis / Q000453:epidemiology; D014605:Uveitis / Q000175:diagnosis / Q000453:epidemiology