title: Use of DNA probes in the diagnosis and treatment of periodontitis --a case series.
abstract: Aggressive periodontitis is characterized by rapid attachment and bone loss with no underlying systemic disease and is associated with specific bacteria like Actinobacillus actinomycetemcomitans (Aa) and Porphyromonas gingivalis (Pg). In this case series 25 patients were diagnosed with aggressive periodontitis by the aid of DNA probes for Aa and Pg and other periodontal pathogens. The use of DNA probes for the detection of periodontal pathogens may aid in the diagnosis and treatment of aggressive periodontitis. Clinical experience suggests that lowering periodontal pathogens to undetectable levels could improve the long-term stability of periodontal health.
authors.affiliation: Department of Operative Dentistry, School of Dental Medicine, University of Mainz, Mainz, Germany.
authors.forename: Gregor-Georg
authors.initials: GG
authors.lastname: Zafiropoulos
authors.forename: Oren
authors.initials: O
authors.lastname: Weiss
authors.forename: Adrian
authors.initials: A
authors.lastname: Kasaj
authors.forename: Brita
authors.initials: B
authors.lastname: Willershausen
authors.forename: Darije
authors.initials: D
authors.lastname: Plancak
mesh_terms: D000328:Adult; D016976:Aggregatibacter actinomycetemcomitans / Q000302:isolation & purification; D015342:DNA Probes; D005260:Female; D006801:Humans; D010514:Periodontal Pocket / Q000382:microbiology; D010518:Periodontitis / Q000175:diagnosis* / Q000382:microbiology* / Q000628:therapy; D016966:Porphyromonas gingivalis / Q000302:isolation & purification; D018713:Prevotella intermedia / Q000302:isolation & purification
chemical_list: D015342:DNA Probes