title: Skin conductance; validation of Skicon-200EX compared to the original model, Skicon-100.
abstract: OBJECTIVE
  Measurement of skin surface and stratum corneum (SC) hydration during experimental trials needs devices with acceptable precision under conditions ranging from decreased, and normal to high hydration. The aim of this study was to validate the recent model of a commonly used device for measurement of skin conductance (Skicon-200EX) vs. the original model (Skicon-100) introduced 20 years ago.
  
  
  METHODS
  Twenty-six healthy Danish volunteers (16 women and 10 men, aged between 22 and 67, with a median age of 42 years) were studied using the Skicon-100 and the Skicon-200EX mounted with three different probes. Normal skin of the cheek, forearm, antecubital fossa, palm, lower leg, and popliteal fossa was studied. The sorption-desorption test was performed on the forearm.
  
  
  RESULTS
  The two instruments displayed closely correlated conductance levels. However, the Skicon-200EX displayed systematically 1.6-fold higher values than the Skicon-100. Different body sites showed different levels depending on anatomical regions. The three probes measured systematically different levels with the original probe measuring lower values. The sorption-desorption test showed high skin conductance values which peaked a few minutes after hydration, in accordance with the original experiments of Tagami.
  
  
  CONCLUSIONS
  The two Skicon instruments evaluated in this study correlated well, however, they displayed different levels depending on instrument main body and probes. Overall, the Skicon-200EX gave 1.6-fold higher value, and this instrument might be more sensitive than the original device, Skicon-100. In scientific reports, the type of instrument main body as well as probe shall be clearly specified.
authors.affiliation: Department of Dermatology, Bispebjerg Hospital, Copenhagen, Denmark. kenmockjp@yahoo.co.jp
authors.forename: Ken-ichiro
authors.initials: K
authors.lastname: O'goshi
authors.forename: Jørgen
authors.initials: J
authors.lastname: Serup
mesh_terms: D000328:Adult; D000368:Aged; D001834:Body Water / Q000378:metabolism*; D004553:Electric Conductivity; D004568:Electrodiagnosis / Q000295:instrumentation*; D004867:Equipment Design; D019544:Equipment Failure Analysis; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D012869:Skin Absorption / Q000502:physiology*; D014159:Transducers