title: Putting presenilins centre stage. Introduction to the Talking Point on the role of presenilin mutations in Alzheimer disease.
authors.affiliation: Laboratory of Neurogenetics, National Institute on Aging, Porter Neuroscience Building, National Institutes of Health Main Campus, Bethesda, Maryland 20892, USA. hardyj@mail.nih.gov
authors.forename: John
authors.initials: J
authors.lastname: Hardy
mesh_terms: D000544:Alzheimer Disease / Q000235:genetics*; D053829:Amyloid Precursor Protein Secretases / Q000235:genetics; D016229:Amyloid beta-Peptides / Q000378:metabolism; D006801:Humans; D009154:Mutation / Q000235:genetics*; D053763:Presenilins / Q000235:genetics*; D011487:Protein Conformation
chemical_list: D016229:Amyloid beta-Peptides; D053763:Presenilins; D053829:Amyloid Precursor Protein Secretases