title: Palmitoylation-dependent protein sorting.
abstract: S-palmitoylation is a posttranslational modification that regulates membrane-protein interactions. However, palmitate is more than just a hydrophobic membrane anchor, as many different types of protein are palmitoylated, including transmembrane proteins. Indeed, there is now compelling evidence that palmitoylation plays a key role in regulating various aspects of protein sorting within the cell.
authors.affiliation: Henry Wellcome Laboratory of Cell Biology, Division of Biochemistry and Molecular Biology, Faculty of Biomedical and Life Sciences, University of Glasgow, Glasgow G12 8QQ, Scotland, UK.
authors.forename: Jennifer
authors.initials: J
authors.lastname: Greaves
authors.forename: Luke H
authors.initials: LH
authors.lastname: Chamberlain
mesh_terms: D000818:Animals; D006801:Humans; D010169:Palmitic Acids / Q000378:metabolism*; D011499:Protein Processing, Post-Translational / Q000502:physiology*; D021381:Protein Transport / Q000502:physiology*
chemical_list: D010169:Palmitic Acids