title: Practical synthesis of chiral 9,9'-spirobixanthene-1,1'-diol.
abstract: A concise four-step synthesis of 9,9'-spirobixanthene-1,1'-diol is reported, featuring a practical preparation at large scale without the use of column chromatography purification. Co-crystallization with N-benzylcinchonidinium chloride and N-benzylquininium chloride rendered the optically pure product in both enantiomers.
authors.affiliation: Department of Chemistry, the Pennsylvania State University, University Park, PA 16802, USA.
authors.forename: Weicheng
authors.initials: W
authors.lastname: Zhang
authors.forename: Shulin
authors.initials: S
authors.lastname: Wu
authors.forename: Zhaoguo
authors.initials: Z
authors.lastname: Zhang
authors.forename: Hemant
authors.initials: H
authors.lastname: Yennawar
authors.forename: Xumu
authors.initials: X
authors.lastname: Zhang
mesh_terms: D008958:Models, Molecular; D015394:Molecular Structure; D013141:Spiro Compounds / Q000138:chemical synthesis*; D014966:Xanthenes / Q000138:chemical synthesis*
chemical_list: C518277:9,9'-spirobixanthene-1,1'-diol; D013141:Spiro Compounds; D014966:Xanthenes