title: [Adipokine and metabolic syndrome].
abstract: Adipose tissue is not simply a depot of energy, but is an active endocrine organ. The adipokines play an important role in the pathogenesis of metabolic syndrome. The proinflammatory adipokines secreted from expanded visceral adipose tissue directly induce insulin resistance and vascular injuries. A better understanding of the endocrine function of adipose tissue may lead to more rational therapy for metabolic syndrome.
authors.affiliation: Shanghai Institute of Endocrine and Metabolic Diseases, Department of Endocrinology, Rui-Jin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, China.
authors.forename: Li-bin
authors.initials: LB
authors.lastname: Zhou
authors.forename: Ming-dao
authors.initials: MD
authors.lastname: Chen
mesh_terms: D052242:Adiponectin / Q000502:physiology*; D000273:Adipose Tissue / Q000503:physiopathology; D015195:Drug Design; D020738:Leptin / Q000502:physiology*; D024821:Metabolic Syndrome / Q000188:drug therapy / Q000503:physiopathology*; D052243:Resistin / Q000502:physiology*; D014409:Tumor Necrosis Factor-alpha / Q000502:physiology
chemical_list: D052242:Adiponectin; D020738:Leptin; D052243:Resistin; D014409:Tumor Necrosis Factor-alpha