title: The balance of thrombosis and hemorrhage in surgery.
abstract: Postoperative hemorrhage and thrombosis is a significant problem during the perioperative period. Understanding the complex and dynamic interplay of factors, proteins, and enzymes during coagulation is imperative to maintain balance between hemostasis and thrombosis. To improve patient outcome, each patient should be risk stratified for bleeding or thrombosis during the preoperative examination. Additional research focused on improvement in screening tools, monitoring, and therapeutic regimens for surgical patients with a coagulopathy are warranted.
authors.affiliation: Department of Medicine, Duke University Medical Center, Box 2622, MSRB, Research Drive, Durham, NC 27710, USA.
authors.forename: George L
authors.initials: GL
authors.lastname: Adams
authors.forename: Roberto J
authors.initials: RJ
authors.lastname: Manson
authors.forename: Immanuel
authors.initials: I
authors.lastname: Turner
authors.forename: David
authors.initials: D
authors.lastname: Sindram
authors.forename: Jeffrey H
authors.initials: JH
authors.lastname: Lawson
mesh_terms: D001777:Blood Coagulation / Q000502:physiology; D006470:Hemorrhage; D006801:Humans; D011183:Postoperative Complications; D013514:Surgical Procedures, Operative; D013927:Thrombosis