title: The Osaka University Aged Twin Registry: epigenetics and identical twins discordant for aging-dependent diseases.
abstract: The Osaka University Aged Twin Registry (OUATR) is the largest adult twin registry in Japan. Since its establishment in 1974, the OUATR has conducted a number of studies with particular focus on the environmental contribution to physical-cognitive-mental aging, longevity and aging-dependent diseases in later adulthood. The registry consists of 12,000 pairs of Japanese twins born between 1900 and 1935. Two hundred and fifty pairs of twins have undergone comprehensive medical examination to date. Follow-up questionnaires have been mailed out on a regular basis, for the purpose of checking current vital statuses, health conditions, and so forth. The main objective of this longitudinal twin study is to contribute to the prevention of lifestyle-related diseases and the promotion of successful aging.
authors.affiliation: Department of Health Promotion Science, Faculty of Medicine, Osaka University, 1-7 Yamadaoka, Suita City, Osaka-fu, Japan. hayakawa@sahs.med.osaka-u.ac.jp
authors.forename: Kazuo
authors.initials: K
authors.lastname: Hayakawa
authors.forename: Kenji
authors.initials: K
authors.lastname: Kato
authors.forename: Miyuki
authors.initials: M
authors.lastname: Onoi
authors.forename: Cai
authors.initials: C
authors.lastname: Yang-Ping
authors.forename: Masao
authors.initials: M
authors.lastname: Kanamori
authors.forename: Syuichi
authors.initials: S
authors.lastname: Doi
authors.forename: Chisato
authors.initials: C
authors.lastname: Hayashi
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Kikuchi
authors.forename: Reiko
authors.initials: R
authors.lastname: Nishihara
authors.forename: Kensuke
authors.initials: K
authors.lastname: Kadota
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000235:genetics*; D004200:Diseases in Twins / Q000235:genetics*; D044127:Epigenesis, Genetic; D005260:Female; D006801:Humans; D007564:Japan; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D012042:Registries; D014430:Twins, Monozygotic