[The study of the oil extract of tea leaf possible teratogenic and embriotoxical action].
The aim of the study was the investigation of possible embriotoxic and teratogenic action of small tea leaf oil extract (TLOE)--a new medicinal agent. The study of embriotoxic and teratogenic properties of TLOE was carried on the 20-day's white rat's young (150g-160g) and males (200g-250g). Experiment included selection of animals and their connubium; definition of the first day of pregnancy; introduction of a drug pregnant female; survey of embryos; processing of embryos, revealing of infringements in an internals and osteal system; statistical processing and comparison of results in relation to the intact control. The results of examination of tea leaf oil extract show no teratogenic and embriotoxic action in peroral therapeutic dose of 737 mg/kg .
Khvedelidze
V
V
Akaki Tsereteli State University; The centre of scientistic national academy of Kutaisi.
Butskhrikidze
B
B
Gordeladze
D
D
Niguriani
N
N
Tsibadze
L
L
D000818:Animals; D001628:Beverages; D004622:Embryo, Mammalian / Q000187:drug effects*; D005260:Female; D008297:Male; D010936:Plant Extracts; D018514:Plant Structures; D051381:Rats; D013723:Teratogens
D010936:Plant Extracts; D013723:Teratogens