Breast cancer proteomics: clinical perspectives.
Breast cancer is the one of leading causes of cancer-related deaths in women within economically developed regions of the world. A major focus of present research into this malignancy is the identification of new biomarkers and drug targets to improve detection and treatment. Proteomics represents one of the latest technological developments in this context. It aims to analyse the complex circuitry of the breast cancer proteome. Here, the authors review how breast cancer proteomics has progressed so far, with emphasis on its potential application to clinically relevant scenarios.
Lau
Thomas Y K
TY
UCD Conway Institute, UCD School of Biomolecular and Biomedical Science, University College Dublin, Belfield, Dublin 4, Ireland.
O'Connor
Darran P
DP
Brennan
Donal J
DJ
Duffy
Michael J
MJ
Pennington
Stephen R
SR
Gallagher
William M
WM
D000818:Animals; D001943:Breast Neoplasms / Q000737:chemistry* / Q000235:genetics* / Q000628:therapy; D005260:Female; D006801:Humans; D020543:Proteome / Q000235:genetics; D040901:Proteomics / Q000379:methods* / Q000639:trends
D020543:Proteome