Catalytic oxidation of imines based on methyltrioxorhenium/urea hydrogen peroxide: a mild and easy chemo- and regioselective entry to nitrones.
[reaction: see text] The first successful catalytic oxidation procedure for the chemoselective conversion of imines to nitrones is reported. The reaction is general, high yielding, and user and environmentally friendly, and furnishes a solution to the yet unanswered issue of regioselective access to nitrones by oxidation of nitrogen derivatives.
Soldaini
Gianluca
G
Dipartimento di Chimica Organica "Ugo Schiff", Laboratorio di Progettazione, Sintesi e Studio di Eterocicli Biologicamente Attivi (HeteroBioLab) and Consorzio INSTM, Università di Firenze, via della Lastruccia 13, I-50019 Sesto Fiorentino (Firenze), Italy.
Cardona
Francesca
F
Goti
Andrea
A
D002384:Catalysis; D006861:Hydrogen Peroxide / Q000737:chemistry*; D007097:Imines / Q000737:chemistry*; D008956:Models, Chemical; D009584:Nitrogen / Q000737:chemistry; D009589:Nitrogen Oxides / Q000138:chemical synthesis*; D009942:Organometallic Compounds / Q000737:chemistry*; D010084:Oxidation-Reduction; D014508:Urea / Q000737:chemistry*
D007097:Imines; D009589:Nitrogen Oxides; D009942:Organometallic Compounds; C015388:nitrones; C411866:methyltrioxorhenium VII; D014508:Urea; D006861:Hydrogen Peroxide; D009584:Nitrogen