title: First experiences with the collagen-elastin matrix Matriderm as a dermal substitute in severe burn injuries of the hand.
abstract: Restoring function after hand burns plays a major role in the restitution of a quality of life. Thereby the reconstructed pliability of the grafted areas is of utmost importance for good hand function. The collagen elastin matrix Matriderm was evaluated as a dermal substitute for the treatment of severe hand burns. In a series of 10 patients, mean age 43 years, TBSA 22.8%, an early debridement and immediate grafting with the matrix and unmeshed skin graft was carried out in a one-stage procedure. In the early postoperative follow up an overall take rate of 97% was observed. In contrast to conventional skin grafts, the color of the skin grafts over the matrix appeared pale in the first few days, but after 2 weeks no difference was observed. After three months, pliability of the grafted area was excellent, (mean VSS 3.2+/-1.2). Full range of motion was achieved in all hands, no blisters and no unstable or hypertrophic scars occurred. Matriderm has proved to be a dermal substitute suitable for the treatment of hand burns. We therefore consider Matriderm as a promising dermal substitute for the treatment of severe hand burns.
authors.affiliation: Division of Plastic and Reconstructive Surgery, Department of Surgery, Medical University of Vienna, Austria.
authors.forename: W
authors.initials: W
authors.lastname: Haslik
authors.forename: L-P
authors.initials: LP
authors.lastname: Kamolz
authors.forename: G
authors.initials: G
authors.lastname: Nathschläger
authors.forename: H
authors.initials: H
authors.lastname: Andel
authors.forename: G
authors.initials: G
authors.lastname: Meissl
authors.forename: M
authors.initials: M
authors.lastname: Frey
mesh_terms: D000328:Adult; D002056:Burns / Q000628:therapy*; D003094:Collagen / Q000627:therapeutic use*; D004549:Elastin / Q000627:therapeutic use*; D005260:Female; D006085:Graft Survival; D006230:Hand Injuries / Q000628:therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D017768:Skin, Artificial; D016896:Treatment Outcome
chemical_list: D003094:Collagen; D004549:Elastin