Choreography of MAGUKs during T cell activation.
T cell receptor activation requires the membrane-associated guanylate kinase CARMA1. A new study finds that a second such kinase, Dlgh1, is also required specifically for activation of the alternative p38 kinase pathway.
Rincón
Mercedes
M
Davis
Roger J
RJ
D048868:Adaptor Proteins, Signal Transducing / Q000235:genetics / Q000378:metabolism*; D000818:Animals; D004789:Enzyme Activation; D016147:Genes, Tumor Suppressor; D008213:Lymphocyte Activation / Q000276:immunology*; D015398:Signal Transduction; D013601:T-Lymphocytes / Q000276:immunology* / Q000378:metabolism*; D048051:p38 Mitogen-Activated Protein Kinases / Q000378:metabolism
D048868:Adaptor Proteins, Signal Transducing; D048051:p38 Mitogen-Activated Protein Kinases