title: Hyperammonemia in generalized Mycobacterium genavense infection after renal transplantation.
abstract: After solid organ transplantation, patients are susceptible to infection caused by uncommon pathogens due the immunosuppressive drug therapy. Here, we report the first case of disseminated Mycobacterium genavense infection in a HIV seronegative renal transplant patient. The most striking clinical feature was a decreased consciousness. Blood results revealed hyperammonemia with otherwise normal liver function. Occurrence of hyperammonemia and massive M. genavense infection has not been reported before.
authors.affiliation: Renal Transplant Unit, Department of Internal Medicine, Academic Medical Center University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam.
authors.forename: S
authors.initials: S
authors.lastname: Nurmohamed
authors.forename: A
authors.initials: A
authors.lastname: Weenink
authors.forename: H
authors.initials: H
authors.lastname: Moeniralam
authors.forename: C
authors.initials: C
authors.lastname: Visser
authors.forename: F
authors.initials: F
authors.lastname: Bemelman
mesh_terms: D000368:Aged; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D022124:Hyperammonemia / Q000175:diagnosis* / Q000382:microbiology; D016030:Kidney Transplantation; D009161:Mycobacterium / Q000302:isolation & purification*; D009164:Mycobacterium Infections / Q000150:complications / Q000175:diagnosis*; D011183:Postoperative Complications / Q000175:diagnosis* / Q000382:microbiology; D013183:Sputum / Q000382:microbiology; D014556:Urine / Q000382:microbiology