title: Linkage disequilibrium, selection and recombination at three Loci.
abstract: Limits to the relationship among linkage disequilibrium, selection and recombination at equilibrium in three-locus, two-allele, deterministic, discrete generation models are determined using linear programming techniques. These results show that the commonly used measures of linkage disequilibrium are not appropriate for a multilocus setting. Additionally, interactions among three loci are important in reducing the strength of selection necessary to maintain a given level of disequilibrium, relative to a two-locus model.
authors.affiliation: Department of Mathematics, University of California, Davis, California 95616.
authors.forename: A
authors.initials: A
authors.lastname: Hastings