The effect of surgical approach on blood flow to the femoral head during resurfacing.
We determined the effect of the surgical approach on perfusion of the femoral head during hip resurfacing arthroplasty by measuring the concentration of cefuroxime in bone samples from the femoral head. A total of 20 operations were performed through either a transgluteal or an extended posterolateral approach. The concentration of cefuroxime in bone was significantly greater when using the transgluteal approach (mean 15.7 mg/kg; 95% confidence interval 12.3 to 19.1) compared with that using the posterolateral approach (mean 5.6 mg/kg; 95% confidence interval 3.5 to 7.8; p < 0.001). In one patient, who had the operation through a posterolateral approach, cefuroxime was undetectable. Using cefuroxime as an indirect measure of blood flow, the posterolateral approach was found to be associated with a significant reduction in the blood supply to the femoral head during resurfacing arthroplasty compared with the transgluteal approach.
Khan
A
A
The Avon Orthopaedic Centre, The University of Western, Australia, Fremantle, Perth, Western Australia.
Yates
P
P
Lovering
A
A
Bannister
G C
GC
Spencer
R F
RF
D000293:Adolescent; D000328:Adult; D000900:Anti-Bacterial Agents / Q000493:pharmacokinetics; D019644:Arthroplasty, Replacement, Hip / Q000379:methods*; D002444:Cefuroxime / Q000493:pharmacokinetics; D005260:Female; D005270:Femur Head / Q000098:blood supply* / Q000378:metabolism; D006801:Humans; D008297:Male; D008875:Middle Aged; D015207:Osteoarthritis, Hip / Q000601:surgery*; D011446:Prospective Studies; D012039:Regional Blood Flow
D000900:Anti-Bacterial Agents; D002444:Cefuroxime