A Lewis acid-Lewis base bifunctional catalyst from a new mixed ligand.
Covalent attachment of quinine to a salen framework through a racemic linker gave a new mixed ligand in a 1:1 diastereomeric mixture, from which an active Lewis acid-Lewis base (LA*-LB*) bifunctional catalyst derived from Co(II) was discovered by the screening of metal complexes. The remarkable intramolecular bifunctional catalytic activity (1 mol % catalyst loading) of the new catalyst was demonstrated using a proof-of-principle reaction. [reaction: see text].
Lin
Yun-Ming
YM
Department of Chemistry, University of Toledo, Toledo, Ohio 43606, USA. yun-ming.lin@utoledo.edu
Boucau
Julie
J
Li
Zhongtao
Z
Casarotto
Virginie
V
Lin
Jinzhen
J
Nguyen
Annie N
AN
Ehrmantraut
Jessica
J