[Recent progress on anti-HIV research of traditional Chinese medicine and components].
This paper summarized the recent 6 years' progress of anti-HIV compounds and traditional Chinese medicines by searching international network and reviewing the domestic and foreign literature. Traditional Chinese medicinal appeared to be a rich source of potentially useful materials for the treatment of human immunodeficiency virus infection. Some of them are much more potent in anti-HIV activity. And some components extracted from the herbs are even more tonic than the crude herb medicines. It has been proved that some active components such as alkaloids, proteins, flavonoids, quercetin, terpene, lignanoid are able to work on anti-HIV. People should pay more attention to the study of traditional Chinese medicine and the leading compounds on anti-HIV/AIDS in the clinic and in the laboratory. So searching for high efficacy and low toxicity anti-HIV drug from traditional Chinese medicine is an important and prospective research direction in the future.
Liu
Zhao-Mei
ZM
College of Life Science and Bioengineering, Beijing University of Technology, Beijing 100022, China. liulzm8004@emails.bjut.edu.cn
Yang
Yi-Shu
YS
Wang
Xiao-Li
XL
Wen
Rui-Xing
RX
D000163:Acquired Immunodeficiency Syndrome / Q000188:drug therapy; D000276:Adjuvants, Immunologic / Q000302:isolation & purification / Q000494:pharmacology*; D000818:Animals; D019380:Anti-HIV Agents / Q000302:isolation & purification / Q000494:pharmacology*; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification / Q000494:pharmacology* / Q000627:therapeutic use; D006678:HIV / Q000187:drug effects*; D006801:Humans; D008516:Medicine, Chinese Traditional; D008517:Phytotherapy; D010946:Plants, Medicinal / Q000737:chemistry*
D000276:Adjuvants, Immunologic; D019380:Anti-HIV Agents; D004365:Drugs, Chinese Herbal