Disease mitigation measures in the control of pandemic influenza.
The threat of an influenza pandemic has alarmed countries around the globe and given rise to an intense interest in disease mitigation measures. This article reviews what is known about the effectiveness and practical feasibility of a range of actions that might be taken in attempts to lessen the number of cases and deaths resulting from an influenza pandemic. The article also discusses potential adverse second- and third-order effects of mitigation actions that decision makers must take into account. Finally, the article summarizes the authors' judgments of the likely effectiveness and likely adverse consequences of the range of disease mitigation measures and suggests priorities and practical actions to be taken.
Inglesby
Thomas V
TV
Center for Biosecurity of the University of Pittsburgh Medical Center, Baltimore, Maryland 21202, USA.
Nuzzo
Jennifer B
JB
O'Toole
Tara
T
Henderson
D A
DA
D004189:Disaster Planning; D006801:Humans; D017053:Infection Control / Q000379:methods* / Q000458:organization & administration*; D007251:Influenza, Human / Q000517:prevention & control*; D014481:United States