Male overactive bladder: the role of urodynamics and anticholinergics.
Millions of men suffer from overactive bladder and lower urinary tract symptoms. The adverse effects on quality of life and costs associated with the condition have been well described. In men, the pathophysiology of lower urinary tract symptoms may be from a number of causes including bladder outlet obstruction, detrusor overactivity, or both. Increasing data and clinical experience support the efficacy and safety of anticholinergics in men; the rate of urinary retention has been equal to that of placebo in short-term studies. Urodynamics play a vital role in defining the bladder and/or outlet dysfunction and help direct one's therapy.
MacDiarmid
Scott
S
Alliance Urology Specialists, Bladder Control and Pelvic Pain Center, 509 N. Elam, Greensboro, NC 27403, USA. smacdiarmid@tucpa.com
Rogers
Alexandra
A
D000328:Adult; D000368:Aged; D001559:Benzhydryl Compounds / Q000627:therapeutic use; D018680:Cholinergic Antagonists / Q000627:therapeutic use*; D003408:Cresols / Q000627:therapeutic use; D003558:Cystoscopy / Q000379:methods; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008333:Mandelic Acids / Q000627:therapeutic use; D008875:Middle Aged; D015337:Multicenter Studies as Topic; D010665:Phenylpropanolamine / Q000627:therapeutic use; D016032:Randomized Controlled Trials as Topic; D018570:Risk Assessment; D012720:Severity of Illness Index; D000068737:Tolterodine Tartrate; D016896:Treatment Outcome; D001748:Urinary Bladder Neck Obstruction / Q000175:diagnosis / Q000188:drug therapy; D053201:Urinary Bladder, Overactive / Q000175:diagnosis* / Q000188:drug therapy*; D014563:Urodynamics
D001559:Benzhydryl Compounds; D018680:Cholinergic Antagonists; D003408:Cresols; D008333:Mandelic Acids; D010665:Phenylpropanolamine; D000068737:Tolterodine Tartrate; C005419:oxybutynin