Discontinuation of secondary prophylaxis against penicilliosis marneffei in AIDS patients after HAART.
A retrospective cohort study was conducted to determine the relapse rate of penicilliosis marneffei after the discontinuation of itraconazole secondary prophylaxis in 33 HIV-infected patients who received HAART and had CD4 cell counts of 100 cells/mul or greater for at least 6 months. The observed incidence of relapse of penicilliosis marneffei was zero cases per 641 person-months (95% confidence interval 0-0.6 cases per person-month) after a median follow-up of 18 months (range 6-45).
Chaiwarith
Romanee
R
Department of Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand.
Charoenyos
Noppawan
N
Sirisanthana
Thira
T
Supparatpinyo
Khuanchai
K
D017088:AIDS-Related Opportunistic Infections / Q000150:complications / Q000517:prevention & control*; D000163:Acquired Immunodeficiency Syndrome / Q000188:drug therapy / Q000276:immunology; D000328:Adult; D000935:Antifungal Agents / Q000008:administration & dosage*; D023241:Antiretroviral Therapy, Highly Active; D018791:CD4 Lymphocyte Count; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D017964:Itraconazole / Q000008:administration & dosage; D008297:Male; D008875:Middle Aged; D009181:Mycoses / Q000150:complications / Q000517:prevention & control*; D010407:Penicillium / Q000302:isolation & purification*; D012008:Recurrence; D012189:Retrospective Studies
D000935:Antifungal Agents; D017964:Itraconazole