title: Aristotle score predicts outcome in patients requiring extracorporeal circulatory support following repair of congenital heart disease.
abstract: Extracorporeal membrane oxygenation (ECMO) has become the standard technique of mechanical support for the failing circulation following repair of congenital heart lesions. The objective of this study was to identify predictors of survival in patients requiring postcardiotomy ECMO. The Aristotle score, a method developed to evaluate quality of care based on complexity, was investigated as a potential predictor of outcome. Between 2003 and 2005, 37 patients required ECMO following corrective surgery for congenital heart disease. Records were reviewed retrospectively with emphasis on factors affecting survival to discharge. The comprehensive Aristotle complexity score was calculated for each patient. Overall, 28 patients (76%) survived to decannulation and 17 patients (46%) survived to discharge. There were 24 (65%) neonates and 10 patients (27%) with single ventricle physiology, with a hospital survival of 42% (10 of 24) and 50% (5 of 10), respectively. Univariate factors associated with survival included Aristotle score, duration of support, reexploration, multiple organ failure, and number of complications. Age, weight, and single-ventricle physiology were not significant. In a logistic regression model, an Aristotle score < 14 was identified as a predictor of survival (OR 0.12, CI 0.02-0.87). The Aristotle score is predictive of outcome in patients requiring postcardiotomy ECMO and may serve as a uniform criterion when comparing and evaluating quality of care and performance in this complex patient population.
authors.affiliation: Nemours Cardiac Center, Alfred I. duPont Hospital for Children, Wilmington, Delaware 19803, USA.
authors.forename: Christopher D
authors.initials: CD
authors.lastname: Derby
authors.forename: Jacek
authors.initials: J
authors.lastname: Kolcz
authors.forename: Paul J
authors.initials: PJ
authors.lastname: Kerins
authors.forename: Daniel R
authors.initials: DR
authors.lastname: Duncan
authors.forename: Emilio
authors.initials: E
authors.lastname: Quezada
authors.forename: Christian
authors.initials: C
authors.lastname: Pizarro
mesh_terms: D006348:Cardiac Surgical Procedures / Q000009:adverse effects / Q000401:mortality*; D015199:Extracorporeal Membrane Oxygenation; D006330:Heart Defects, Congenital / Q000601:surgery*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D011787:Quality of Health Care; D012189:Retrospective Studies; D015996:Survival Rate