2'-Hydroxycinnamaldehyde from stem bark of Cinnamomum cassia.
2'-Hydroxycinnamaldehyde, which inhibits farnesyl-protein transferase (FPTase), has been isolated from the stem bark of Cinnamomum cassia Blume. The biologically active agent in the extract has been purified by silica column chromatography and HPLC. The structure of the isolated compound was elucidated on the basis of 500 MHz NMR experiments.
Kwon
B M
BM
Cho
Y K
YK
Lee
S H
SH
Nam
J Y
JY
Bok
S H
SH
Chun
S K
SK
Kim
J A
JA
Lee
I R
IR