Reactivity of hydroxybenzoic acids in the hydrogen-isotope exchange reaction.
The hydrogen-isotope exchange reaction (T-for-H exchange reaction) between tritiated water vapor (HTO vapor) and 3-hydroxy-4-methoxybenzoic acid (and it's analog; 4-hydroxy-3-methoxybenzoic acid) were observed at 50 and 70 degrees C in a gas-solid system to reveal the reactivity of a functional group in an aromatic compound having two substituents in the aromatic ring. Further, it was shown that (a) the reactivity of the compounds used in this work follows the Hammett's rule, and (b) the reactivity of trisubstituted aromatic compound could be analyzed by applying the additive property of the Hammett's rule even if the compound contains a substituent at the ortho-position.
Zhao
D
D
School of Chemistry and Materials Science, Heilongjiang University, Harbin 150080, China. zhaodyu@hlju.edu.cn
Imaizumi
H
H
Lei
Q
Q
Wu
J
J
D006859:Hydrogen / Q000737:chemistry*; D062385:Hydroxybenzoates / Q000737:chemistry*; D007554:Isotopes / Q000737:chemistry; D014316:Tritium / Q000737:chemistry*; D014867:Water / Q000737:chemistry*
D062385:Hydroxybenzoates; D007554:Isotopes; D014867:Water; D014316:Tritium; D006859:Hydrogen