title: Ring-expansion of tertiary cyclic alpha-vinylamines by tandem conjugate addition to (p-toluenesulfonyl)ethyne and formal 3-aza-Cope rearrangement.
abstract: A novel ring-expansion protocol is based on the conjugate additions of cyclic alpha-vinylamines to (p-toluenesulfonyl)ethyne, followed by aza-Cope rearrangements of the resulting zwitterions, to afford medium and large-ring cyclic amines under remarkably mild conditions.
authors.affiliation: Department of Chemistry, University of Calgary, Calgary, AB, CanadaT2N 1N4.
authors.forename: Mitchell H
authors.initials: MH
authors.lastname: Weston
authors.forename: Katsumasa
authors.initials: K
authors.lastname: Nakajima
authors.forename: Masood
authors.initials: M
authors.lastname: Parvez
authors.forename: Thomas G
authors.initials: TG
authors.lastname: Back