Chemical constituents of Isatis indigotica.
From the roots of Isatis indigotica, ten compounds (1-10) were isolated. Compound 1 is a new alkaloid whose structure was elucidated as (E)-3-(3',5'-dimethoxy-4'-hydroxy-benzylidene)-2-indolinone. Compounds 2-4 were discovered for the first time from a natural source and compounds 5-7 were originally isolated from this species. In a preliminary study, compounds 4-8 showed antiendotoxic activities in vitro.
Wu
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Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 200031, China.
Liu
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Sheng
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Sun
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Qin
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