title: Efficient ruthenium and copper cocatalzyed five-component coupling to form dipropargyl amines under mild conditions in water.
abstract: Dipropargyl amines are synthesized by a double direct alkynylation of primary followed by secondary imines formed in situ during an efficient, five-component, one-pot coupling reaction cocatalyzed by ruthenium and copper in water.
authors.affiliation: Department of Chemistry, McGill University, 801 Sherbrooke St. West, Montreal, Quebec H3A 2K6, Canada.
authors.forename: E Ryan
authors.initials: ER
authors.lastname: Bonfield
authors.forename: Chao-Jun
authors.initials: CJ
authors.lastname: Li
mesh_terms: D000480:Alkynes / Q000737:chemistry; D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D007097:Imines / Q000737:chemistry*; D008956:Models, Chemical; D010293:Pargyline / Q000031:analogs & derivatives* / Q000138:chemical synthesis; D011437:Propylamines / Q000138:chemical synthesis*; D012428:Ruthenium / Q000737:chemistry*; D014867:Water / Q000737:chemistry*
chemical_list: D000480:Alkynes; D007097:Imines; D011437:Propylamines; D014867:Water; C009054:propargylamine; D003300:Copper; D012428:Ruthenium; D010293:Pargyline