title: A designed RNA shuts down transcription.
abstract: Using an in vivo selection strategy, Kehayova and Liu identified an RNA molecule capable of silencing gene transcription in yeast . In doing so, they expand the repertoire of RNA molecules performing long-believed "protein-only" cellular functions.
authors.affiliation: Lehrstuhl für Mikrobiologie, Friedrich-Alexander-Universität Erlangen-Nürnberg, Staudtstr. 5, 91058 Erlangen, Germany.
authors.forename: Julia E
authors.initials: JE
authors.lastname: Weigand
authors.forename: Beatrix
authors.initials: B
authors.lastname: Suess
mesh_terms: D015195:Drug Design; D020868:Gene Silencing / Q000187:drug effects; D005818:Genetic Engineering; D012313:RNA / Q000737:chemistry / Q000494:pharmacology*; D014158:Transcription, Genetic / Q000187:drug effects*; D015003:Yeasts
chemical_list: D012313:RNA