A case report of nonepisodic angioedema with eosinophilia in a Korean patient and a review of the Korean literature.
Episodic angioedema with eosinophilia (EAE) is characterized by recurrent angioedema, peripheral eosinophilia, elevated serum IgM, fever, weight gain, and a benign course lacking any internal organ involvement. Dozens of cases of the nonepisodic variant (NEAE), which is limited to a single attack, have been reported in Japan. These NEAE cases normally have been less severe than the episodic type. In this paper, we describe the case of a Korean patient whose clinical and laboratory findings were consistent with NEAE, and review five other cases of EAE and NEAE reported in the Korean literature. The Korean NEAE cases outlined in this paper demonstrate that, as in Japan, NEAE is not uncommon in Korea, and also suggest that this disease exhibits a cultural predilection for Asian populations.
Jang
Ji Sun
JS
Department of Internal Medicine, College of Medicine, Hallym University, Seoul, Korea.
Kim
Chang-Hwan
CH
Kim
Sang-Seok
SS
Oh
Ji Eun
JE
Park
Yong-Bum
YB
Lee
Jae-Young
JY
Mo
Eun-Kyung
EK
D000328:Adult; D000799:Angioedema / Q000150:complications* / Q000473:pathology; D001706:Biopsy; D003937:Diagnosis, Differential; D004802:Eosinophilia / Q000150:complications* / Q000473:pathology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007723:Korea; D012867:Skin / Q000473:pathology