title: Implantable cardioverter-defibrillator infection due to Brucella melitensis: case report and review of brucellosis of cardiac devices.
abstract: We report a case of implantable cardioverter-defibrillator infection due to Brucella melitensis and review 5 previously reported cases of Brucella infection of cardiac devices. Device removal, followed by antibiotic therapy for 6 weeks, is probably required for cure. Although rare, reports of Brucella infection of prosthetic implants and devices have increased in the past decade. Brucellosis should be considered in the differential diagnosis of cardiac device infection in patients residing in or traveling to areas of endemicity.
authors.affiliation: Division of Geographic Medicine and Infectious Diseases, Tufts-New England Medical Center, Boston, Massachusetts.
authors.forename: Abhay
authors.initials: A
authors.lastname: Dhand
authors.forename: John J
authors.initials: JJ
authors.lastname: Ross
mesh_terms: D000368:Aged; D017347:Brucella melitensis / Q000302:isolation & purification*; D002006:Brucellosis / Q000175:diagnosis / Q000188:drug therapy* / Q000382:microbiology; D002939:Ciprofloxacin / Q000627:therapeutic use; D017147:Defibrillators, Implantable / Q000009:adverse effects* / Q000382:microbiology; D020878:Device Removal; D004318:Doxycycline / Q000627:therapeutic use; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D016459:Prosthesis-Related Infections / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D019233:Retreatment; D018570:Risk Assessment; D016896:Treatment Outcome
chemical_list: D002939:Ciprofloxacin; D004318:Doxycycline