Two novel dicarboxylic Acid derivatives and a new dimeric hydrolyzable tannin from walnuts.
In addition to the 16 previously reported polyphenols including 3 new ellagitannins, 2 novel dicarboxylic acid derivatives, glansreginins A (1) and B (2), and a new dimeric hydrolyzable tannin, glansrin D (3), were isolated, together with 15 known compounds from walnuts, the seeds of Juglans regia. The structures of the new compounds were elucidated on the basis of 1D- and 2D-NMR analyses and chemical data. The antioxidant effect of these isolates was also evaluated by SOD-like and DPPH radical scavenging activities.
Ito
Hideyuki
H
Department of Pharmacognosy, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Tsushima, Okayama 700-8530, Japan. hito@cc.okayama-u.ac.jp
Okuda
Takahiro
T
Fukuda
Toshiyuki
T
Hatano
Tsutomu
T
Yoshida
Takashi
T
D000975:Antioxidants / Q000494:pharmacology; D003998:Dicarboxylic Acids / Q000032:analysis*; D019281:Dimerization; D005419:Flavonoids / Q000032:analysis; D006868:Hydrolysis; D047348:Hydrolyzable Tannins / Q000032:analysis / Q000737:chemistry / Q000494:pharmacology; D031324:Juglans / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D010636:Phenols / Q000032:analysis; D059808:Polyphenols; D012639:Seeds / Q000737:chemistry; D013634:Tannins / Q000032:analysis* / Q000737:chemistry*
D000975:Antioxidants; D003998:Dicarboxylic Acids; D005419:Flavonoids; D047348:Hydrolyzable Tannins; D010636:Phenols; D059808:Polyphenols; D013634:Tannins; C519268:glansrin D