[Posttraumatic hyperkinésie volitionnelle was markedly improved by Vim thalamic deep brain stimulation].
A 69-year-old man presented with hyperkinésie volitionnelle (HV) one year after a brain injury. We considered diffuse axonal injury (DAI) as the cause of HV in this patient. Neither three-dimensional anisotropy contrast magnetic resonance axonography (3DAC-MRX) nor movement-related cortical potential (MRCP) measurements revealed any abnormal findings. These suggest that the cerebellar efferent pathways were intact. Vim deep brain stimulation (DBS) markedly improved HV, which was resistant to clonazepam. This study demonstrated that traumatic brain injury can cause the tremor type of HV even when the cerebellar efferent pathways are intact, and that Vim DBS is an alternative treatment for HV that is unresponsive to drugs.
Takado
Yuhei
Y
Department of Neurology, Brain Research Institute, Niigata University.
Shimohata
Takayoshi
T
Terajima
Kenshi
K
Suwazono
Shugo
S
Kameyama
Shigeki
S
Tanaka
Keiko
K
Nishizawa
Masatoyo
M
D000368:Aged; D001369:Axons / Q000473:pathology; D002540:Cerebral Cortex / Q000503:physiopathology; D046690:Deep Brain Stimulation / Q000379:methods*; D020833:Diffuse Axonal Injury / Q000150:complications* / Q000175:diagnosis / Q000473:pathology / Q000503:physiopathology; D019054:Evoked Potentials, Motor; D006801:Humans; D006948:Hyperkinesis / Q000209:etiology* / Q000628:therapy*; D007091:Image Processing, Computer-Assisted; D008279:Magnetic Resonance Imaging; D008297:Male; D016896:Treatment Outcome; D020651:Ventral Thalamic Nuclei