[Galectin-3 immunodetection in thyroid fine-needle aspirates: technical procedure and results].
Fine-needle aspiration cytology of thyroid nodules is an excellent diagnostic tool. However, in about 20% cases of the so-called undeterminate lesions, cytological findings are inconclusive as distinction between benign from malignant lesions is difficult. Less than 20% of such undeterminate lesions will be malignant after histological diagnosis. Several molecular markers of thyroid malignancy are under investigation, among them Galectin-3. Here we present a study of this marker performed on fine-needle aspiration samples including description of an easy to implement technical procedure.
Collet
Jean-François
JF
Cabinet de Cyto-Pathologie, 11 rue Cambronne, 75015 Paris. ajfcollet@wanadoo.fr
Fajac
Anne
A
D014408:Biomarkers, Tumor / Q000032:analysis*; D044963:Biopsy, Fine-Needle / Q000379:methods*; D037502:Galectin 3 / Q000032:analysis*; D006801:Humans; D016606:Thyroid Nodule / Q000737:chemistry* / Q000473:pathology*
D014408:Biomarkers, Tumor; D037502:Galectin 3