Acquired generalised neuromyotonia, cutaneous lupus erythematosus and alopecia areata in a patient with myasthenia gravis.
We describe a patient with the diagnoses of acquired neuromyotonia, cutaneous lupus erythematosus and alopecia areata, occurring many years after a thymectomy for myasthenia gravis associated with a thymoma. We review the current literature on autoimmune conditions associated with myasthenia gravis and thymectomy. To our knowledge, this combination of multiple autoimmune conditions has not been reported previously.
O'Sullivan
Sean S
SS
Department of Neurology and Neurophysiology, Cork University Hospital, Wilton, Cork, Ireland. sosulliv@ion.ucl.ac.uk
Mullins
Gerard M
GM
Neligan
Aidan
A
McNamara
Brian
B
Galvin
Roderick J
RJ
D000506:Alopecia Areata / Q000175:diagnosis* / Q000276:immunology; D000974:Antibodies, Antinuclear / Q000097:blood; D001323:Autoantibodies / Q000097:blood; D001327:Autoimmune Diseases / Q000175:diagnosis* / Q000276:immunology; D002220:Carbamazepine / Q000627:therapeutic use; D005260:Female; D006801:Humans; D020386:Isaacs Syndrome / Q000175:diagnosis* / Q000188:drug therapy / Q000276:immunology; D008178:Lupus Erythematosus, Cutaneous / Q000175:diagnosis* / Q000276:immunology; D008875:Middle Aged; D009157:Myasthenia Gravis / Q000175:diagnosis* / Q000276:immunology / Q000601:surgery; D009460:Neurologic Examination; D011183:Postoperative Complications / Q000175:diagnosis / Q000276:immunology; D024642:Potassium Channels, Voltage-Gated / Q000276:immunology; D011950:Receptors, Cholinergic / Q000276:immunology; D013934:Thymectomy; D013945:Thymoma / Q000175:diagnosis / Q000276:immunology / Q000601:surgery; D013953:Thymus Neoplasms / Q000175:diagnosis / Q000276:immunology / Q000601:surgery
D000974:Antibodies, Antinuclear; D001323:Autoantibodies; D024642:Potassium Channels, Voltage-Gated; D011950:Receptors, Cholinergic; D002220:Carbamazepine