title: Pretreatment tumor lysis syndrome associated with bulky retroperitoneal tumors. Recognition is the mainstay of therapy.
abstract: Acute pretreatment tumor lysis syndrome is a rare complication of cancer. Early recognition and aggressive management are mandatory for prevention of the adverse sequelae of the syndrome. Here we present 2 cases of pretreatment tumor lysis syndrome, concluding that this clinical entity should be in the differential diagnosis of acute renal failure associated with malignancy, as early recognition is in fact the mainstay of treatment.
authors.affiliation: First Department of Propaedeutic Surgery, Hippocrateion Hospital, Athens Medical School, University of Athens, Athens, Greece.
authors.forename: Dimitrios
authors.initials: D
authors.lastname: Theodorou
authors.forename: Emmanuel
authors.initials: E
authors.lastname: Lagoudianakis
authors.forename: Michael
authors.initials: M
authors.lastname: Pattas
authors.forename: Panagiotis
authors.initials: P
authors.lastname: Drimousis
authors.forename: Dimitrios K
authors.initials: DK
authors.lastname: Tsekouras
authors.forename: Michael
authors.initials: M
authors.lastname: Genetzakis
authors.forename: Vagelogiannis
authors.initials: V
authors.lastname: Katergiannakis
authors.forename: Andreas
authors.initials: A
authors.lastname: Manouras
mesh_terms: D000208:Acute Disease; D058186:Acute Kidney Injury / Q000175:diagnosis; D000328:Adult; D003937:Diagnosis, Differential; D042241:Early Diagnosis; D005260:Female; D006801:Humans; D008297:Male; D012186:Retroperitoneal Neoplasms / Q000150:complications*; D015275:Tumor Lysis Syndrome / Q000175:diagnosis* / Q000209:etiology / Q000473:pathology / Q000628:therapy*