Allelic Variants at the Xanthine Dehydrogenase Locus Affecting Enzyme Activity in DROSOPHILA PSEUDOOBSCURA.
Quantitative studies of enzyme activity on gels show about four-fold differences in enzyme activity of different xanthine dehydrogenase (XDH ) alleles. At least three different activity classes could be distinguished among the 23 strains isogenic for the XDH locus. No association of high activity with the high frequency electromorph was observed; instead, the low frequency electromorphs had 0.5 to 2 times the activity of the high frequency electromorph. The frequency of low activity, high activity and intermediate activity XDH alleles among these 23 lines is 0.13, 0.09, and 0.78, respectively.
Prakash
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Department of Biology, University of Rochester, Rochester, New York 14627.