Heavy tools for genome mining.
In this issue of Chemistry & Biology, Gross et al. report development of a novel genome mining method for isolating products of orphan biosynthetic gene clusters, and the application of this method to the isolation of orfamide A, a novel cyclic lipopeptide.
Corre
Christophe
C
Department of Chemistry, University of Warwick, Coventry CV4 7AL, United Kingdom.
Challis
Gregory L
GL
D001688:Biological Products / Q000302:isolation & purification; D019295:Computational Biology / Q000379:methods*; D023281:Genomics / Q000379:methods*; D008074:Lipoproteins / Q000302:isolation & purification; D010456:Peptides, Cyclic / Q000302:isolation & purification
D001688:Biological Products; D008074:Lipoproteins; D010456:Peptides, Cyclic