Type II polyketide synthases: gaining a deeper insight into enzymatic teamwork.
This review covers advances in understanding of the biosynthesis of polyketides produced by type II PKS systems at the genetic, biochemical and structural levels.
Hertweck
Christian
C
Leibniz Institute for Natural Product Research and Infection Biology, HKI, Beutenbergstrasse 11a, 07745 Jena, Germany.
Luzhetskyy
Andriy
A
Rebets
Yuri
Y
Bechthold
Andreas
A
D018942:Macrolides / Q000378:metabolism; D008958:Models, Molecular; D048630:Polyketide Synthases / Q000096:biosynthesis / Q000145:classification / Q000378:metabolism; D013302:Streptomyces / Q000201:enzymology*
D018942:Macrolides; D048630:Polyketide Synthases