title: Asthma and Churg-Strauss syndrome.
abstract: We report the case of a 25-year-old woman with Churg-Strauss syndrome, the symptoms of which had first appeared soon after she began taking oral contraceptive at the age of sixteen. The clinical profile evolved rapidly to severe persistent asthma, nasal polyposis, perennial obstructive rhinitis, eosinophilia (peripheral/tissue) and mononeuritis. Churg-Strauss syndrome is the type of disease that demands early detection, accurate diagnosis, aggressive treatment and periodic monitoring. It should be considered in the differential diagnosis of moderate and severe persistent asthma. The case reported calls attention to possibility that there is a hormonal component and that the disease can present early onset.
authors.affiliation: São Zacarias Hospital, Rio de Janeiro, Brazil.
authors.forename: Soloni Afra Pires
authors.initials: SA
authors.lastname: Levy
authors.forename: Alfeu Tavares
authors.initials: AT
authors.lastname: França
authors.forename: Denise
authors.initials: D
authors.lastname: de La Reza
authors.forename: Solange Oliveira Rodrigues
authors.initials: SO
authors.lastname: Valle
authors.forename: Ana Helena Pereira
authors.initials: AH
authors.lastname: Correia
mesh_terms: D000328:Adult; D001249:Asthma / Q000175:diagnosis*; D001706:Biopsy; D015267:Churg-Strauss Syndrome / Q000139:chemically induced / Q000175:diagnosis* / Q000188:drug therapy; D003271:Contraceptive Agents, Female / Q000009:adverse effects*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D012720:Severity of Illness Index; D014057:Tomography, X-Ray Computed
chemical_list: D003271:Contraceptive Agents, Female