title: Central corneal thickness and visual field progression in patients with chronic primary angle-closure glaucoma with low intraocular pressure.
abstract: OBJECTIVE
  To determine the association of central corneal thickness (CCT) and visual field progression in patients with chronic primary angle-closure glaucoma (CPACG) with low intraocular pressure (IOP).
  
  
  METHODS
  Retrospective, comparative case series.
  
  
  METHODS
  A total of 163 eyes with CPACG and sustained IOP <18 mm Hg were included. Initial and three-year after mean deviation (MD) on Humphrey field analyzer and CCT with ultrasonic pachymetry were recorded. On the basis of the CCT value, the sample was split in two groups (group 1 <540 microm; group 2 > or =540 microm).
  
  
  RESULTS
  Mean CCT was 525.8 +/- 11.6 microm in group 1 and 574.4 +/- 24.0 microm in group 2. There was no significant difference for initial MD (P = .979), but a significant difference was found between two groups for follow-up MD (P = .023).
  
  
  CONCLUSIONS
  Patients with CPACG with a thinner cornea are at greater risk for visual field progression even if they maintain a low IOP after treatment.
authors.affiliation: Institute of Vision Research, Department of Ophthalmology, Yonsei University College of Medicine, Seoul, Korea.
authors.forename: Samin
authors.initials: S
authors.lastname: Hong
authors.forename: Chan Yun
authors.initials: CY
authors.lastname: Kim
authors.forename: Gong Je
authors.initials: GJ
authors.lastname: Seong
authors.forename: Young Jae
authors.initials: YJ
authors.lastname: Hong
mesh_terms: D001837:Body Weights and Measures; D002452:Cell Count; D002908:Chronic Disease; D003315:Cornea / Q000000981:diagnostic imaging / Q000473:pathology*; D018450:Disease Progression; D005260:Female; D015812:Glaucoma, Angle-Closure / Q000150:complications*; D006801:Humans; D007429:Intraocular Pressure; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012307:Risk Factors; D014463:Ultrasonography; D014786:Vision Disorders / Q000209:etiology* / Q000503:physiopathology; D058609:Visual Field Tests; D014794:Visual Fields