Time-resolved, 3-dimensional magnetic resonance flow analysis at 3 T: visualization of normal and pathological aortic vascular hemodynamics.
Flow-sensitive 3-dimensional magnetic resonance imaging at 3 T and advanced 3-dimensional visualization were used to visualize local and global vascular hemodynamics in the thoracic aorta. In patients with pathological geometric alterations of the thoracic aorta, this technique revealed considerable changes in local blood flow characteristics, compared with normal volunteers. Specifically, relatively small geometric changes, such as a partially thrombosed aortic arch or a mild aneurysm of the ascending aorta, resulted in major disturbances of local blood flow patterns within and even further downstream to the pathology.
Frydrychowicz
Alex
A
Department of Diagnostic Radiology, University Hospital Freiburg, Freiburg, Germany.
Harloff
Andreas
A
Jung
Bernd
B
Zaitsev
Maxim
M
Weigang
Ernst
E
Bley
Thorsten A
TA
Langer
Mathias
M
Hennig
Jürgen
J
Markl
Michael
M
D000328:Adult; D001013:Aorta, Thoracic / Q000473:pathology* / Q000502:physiology / Q000503:physiopathology*; D005260:Female; D006801:Humans; D021621:Imaging, Three-Dimensional; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D012039:Regional Blood Flow; D013997:Time Factors