Geldanamycin induces CHOP expression through a 4-(2-aminoethyl)-benzenesulfonyl fluoride-responsive serine protease.
Hosoi
Toru
T
Hyoda
Kanae
K
Okuma
Yasunobu
Y
Nomura
Yasuyuki
Y
Ozawa
Koichiro
K
D000818:Animals; D016227:Benzoquinones / Q000494:pharmacology*; D002460:Cell Line; D018841:HSP90 Heat-Shock Proteins / Q000037:antagonists & inhibitors; D047029:Lactams, Macrocyclic / Q000494:pharmacology*; D051379:Mice; D012697:Serine Endopeptidases / Q000502:physiology*; D015842:Serine Proteinase Inhibitors / Q000494:pharmacology*; D013450:Sulfones / Q000494:pharmacology*; D051742:Transcription Factor CHOP / Q000096:biosynthesis / Q000235:genetics*
D016227:Benzoquinones; D018841:HSP90 Heat-Shock Proteins; D047029:Lactams, Macrocyclic; D015842:Serine Proteinase Inhibitors; D013450:Sulfones; D051742:Transcription Factor CHOP; C002010:4-(2-aminoethyl)benzenesulfonylfluoride; D012697:Serine Endopeptidases; C001277:geldanamycin