Angiogenic and anti-angiogenic factors in adrenal tumours.
It appears that neoangiogenesis is an important factor in tumour invasion and the formation of metastases in several human cancers, and studies on pro-angiogenic and antiangiogenic factors are therefore of considerable interest to researchers. In this review we present pro-angiogenic and anti-angiogenic factors and other growth factors and their role in the formation of new blood vessels in adrenal tumours. Assessment of the angiogenic status of adrenal tumours and their vascular pattern may be useful for discriminating benign from malignant lesions and knowledge of their angiogenesis may be essential to the drawing up of promising treatment strategies for patients with malignant tumours.
Jurczyńska
Jolanta
J
Clinic of Endocrinology, Medical University, Lodz. jjurczynska@wp.pl
Zieleniewski
Wojciech
W
Stepień
Henryk
H
Komorowski
Jan
J
D000310:Adrenal Gland Neoplasms / Q000503:physiopathology*; D000311:Adrenal Glands / Q000098:blood supply*; D043925:Angiogenesis Inducing Agents / Q000378:metabolism*; D020533:Angiogenesis Inhibitors / Q000378:metabolism*; D000818:Animals; D006801:Humans; D009389:Neovascularization, Pathologic / Q000503:physiopathology; D018919:Neovascularization, Physiologic / Q000502:physiology
D043925:Angiogenesis Inducing Agents; D020533:Angiogenesis Inhibitors