title: Field trial of two dual vaccines against Mycoplasma agalactiae and Mycoplasma mycoides subsp. mycoides (large colony type) in goats.
abstract: Two vaccines against Mycoplasma agalactiae and Mycoplasma mycoides subsp. mycoides (LC type) were developed using inactivated strains selected in previous characterization studies. The vaccines differed in terms of the adjuvants used: aluminium hydroxide (vaccine A) or aluminium hydroxide plus purified saponin (vaccine B). These vaccines were tested on 60 pregnant goats and 60 seronegative kids that were challenged by placing in a herd with a history of caprine contagious agalactia (CCA). Our findings indicate the effectiveness of the vaccines in preventing the appearance of new clinical signs such as mastitis, abortion, pneumonia and polyarthritis in CCA affected herds.
authors.affiliation: Unidad de Epidemiología y Medicina Preventiva, Facultad de Veterinaria, Universidad de Las Palmas, Trasmontaña s/n, 35416 Arucas, Spain. cdelafe@um.es
authors.forename: Christian
authors.initials: C
authors.lastname: de la Fe
authors.forename: Patricia
authors.initials: P
authors.lastname: Assunção
authors.forename: Pedro
authors.initials: P
authors.lastname: Saavedra
authors.forename: Sebastiana
authors.initials: S
authors.lastname: Tola
authors.forename: Carlos
authors.initials: C
authors.lastname: Poveda
authors.forename: José B
authors.initials: JB
authors.lastname: Poveda
mesh_terms: D000276:Adjuvants, Immunologic / Q000008:administration & dosage; D000818:Animals; D000907:Antibodies, Bacterial / Q000097:blood; D001428:Bacterial Vaccines / Q000008:administration & dosage / Q000276:immunology*; D004269:DNA, Bacterial / Q000032:analysis; D005260:Female; D006041:Goats; D008892:Milk / Q000382:microbiology; D009175:Mycoplasma Infections / Q000097:blood / Q000276:immunology* / Q000517:prevention & control; D045644:Mycoplasma agalactiae / Q000235:genetics / Q000254:growth & development / Q000276:immunology*; D009176:Mycoplasma mycoides / Q000235:genetics / Q000254:growth & development / Q000276:immunology*; D016133:Polymerase Chain Reaction; D011247:Pregnancy; D014611:Vaccination / Q000379:methods
chemical_list: D000276:Adjuvants, Immunologic; D000907:Antibodies, Bacterial; D001428:Bacterial Vaccines; D004269:DNA, Bacterial