Antimicrobial activity of Tunisian quince (Cydonia oblonga Miller) pulp and peel polyphenolic extracts.
Quince (Cydonia oblonga Miller) fruit aqueous acetone extracts were evaluated. High-performance liquid chromatography-diode array detection and electrospray ionization-mass spectrometry were used for the identification and quantification of the phenolic compounds. The total phenolic content of the pulp and peel parts ranged from 37 to 47 and 105 to 157 mg/100 g of fresh weight, respectively. Chlorogenic acid (5-O-caffeoylquinic acid) was the most abundant phenolic compound in the pulp (37%), whereas rutin (quercetin 3-O-rutinoside) was the main one in the peel (36%). The radical scavenging potential of the extracts was determined and compared with that of synthetic antioxidants. The stronger properties corresponded to those obtained from peel material with a 70-80% inhibitory effect on DPPH radicals. The antimicrobial activity of the extracts against different microorganism strains was also investigated. Quince peel extract was the most active for inhibiting bacteria growth with minimum inhibitory and bactericide concentrations in the range of 102-5 x 103 microg polyphenol/mL. It seems that chlorogenic acid acts in synergism with other components of the extracts to exhibit their total antimicrobial activities.
Fattouch
Sami
S
Biological Engineering Laboratory, National Institute of Applied Sciences and Technology, Tunis 1080, Tunisia. Sami.Fattouch@insat.rnu.tn
Caboni
Pierluigi
P
Coroneo
Valentina
V
Tuberoso
Carlo I G
CI
Angioni
Alberto
A
Dessi
Sandro
S
Marzouki
Nejib
N
Cabras
Paolo
P
D000890:Anti-Infective Agents / Q000494:pharmacology*; D000975:Antioxidants / Q000494:pharmacology; D002726:Chlorogenic Acid / Q000032:analysis; D005419:Flavonoids / Q000032:analysis* / Q000494:pharmacology*; D005638:Fruit / Q000737:chemistry*; D010636:Phenols / Q000032:analysis* / Q000494:pharmacology*; D010936:Plant Extracts / Q000737:chemistry / Q000494:pharmacology; D059808:Polyphenols; D027824:Rosaceae / Q000737:chemistry*; D012431:Rutin / Q000032:analysis
D000890:Anti-Infective Agents; D000975:Antioxidants; D005419:Flavonoids; D010636:Phenols; D010936:Plant Extracts; D059808:Polyphenols; D002726:Chlorogenic Acid; D012431:Rutin