[Long-term regulation of arterial pressure and essential hypertension--I. Long-term regulation of arterial pressure].
Arterial blood pressure is regulated not by a single pressure controlling mechanism but instead by several interrelated mechanisms, each of which performs a specific function. By now, it is clear that kidney plays a dominant role in long-term regulation of arterial pressure. It is found that urine volume output markedly increases as the arterial blood pressure rises. It is the phenomenon of pressure-diuresis. Arterial blood pressure can be kept constantly by the action of pressure-diuresis when the excess accumulation of extracellular fluid in the body occurs. During this period of time kidney excretes a larger amount of urine volume. It is thus that under the conditions of the excess accumulation of extracellular fluid in the body, high level of the arterial blood pressure can only be observed as the renal function is abnormal.
Fan
Shao-Guang
SG
Department of Physiology, School of Basic Medical Sciences, Peking University Health Science Center, Beijing 100083, China.
Wu
Jing
J
Lv
Ang
A
D001158:Arteries / Q000503:physiopathology*; D001794:Blood Pressure / Q000502:physiology; D006801:Humans; D006973:Hypertension / Q000503:physiopathology*; D007668:Kidney / Q000503:physiopathology