title: Evaluation of six years allergen immunotherapy in allergic rhinitis and allergic asthma.
abstract: Allergen immunotherapy involves the administration of gradually increasing quantities of specific allergens to patients with IgE-mediated conditions until a dose is reached that is effective in reducing disease severity from natural exposure. In the present study we evaluated a period of six years immunotherapy allergic rhinitis and allergic asthma patients with positive skin prick test of common aeroallergen. The immunotherapy was performed on 156 patients. One hundred twenty of the cases were allergic rhinitis (80%), 29 cases had allergic asthma and 7 cases were mixed (4.5%). 70% in allergic rhinitis group, 75% in allergic asthma group and 42.8% in mixed group completely improved. Immunotherapy, an older therapeutic method, has now been updated, and with appropriate indications, precautions and methods, has been clearly shown to be effective in the treatment of allergic rhinitis and in some cases of asthma and insect hypersensitivity.
authors.affiliation: Immunology Research Centre, Buali Research Institute, Mashhad University of Medical Sciences, Mashhad, Iran.
authors.forename: Reza
authors.initials: R
authors.lastname: Farid
authors.forename: Ramin
authors.initials: R
authors.lastname: Ghasemi
authors.forename: Mahmood
authors.initials: M
authors.lastname: Baradaran-Rahimi
authors.forename: Farahzad
authors.initials: F
authors.lastname: Jabbari
authors.forename: Javad
authors.initials: J
authors.lastname: Ghaffari
authors.forename: Hooshang
authors.initials: H
authors.lastname: Rafatpanah
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000485:Allergens / Q000627:therapeutic use*; D001249:Asthma / Q000188:drug therapy*; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012221:Rhinitis, Allergic, Perennial / Q000188:drug therapy*; D006255:Rhinitis, Allergic, Seasonal / Q000188:drug therapy*
chemical_list: D000485:Allergens