title: Cryptococcal meningitis in a patient treated with infliximab.
abstract: Infliximab, a tumor necrosis factor-alpha inhibitor, is increasingly used for the therapy of different inflammatory conditions. We report the first case of cryptococcal meningitis in a patient treated with infliximab and other immunosuppressive agents, and review a further 5 reported cryptococcal infections. All of them involved fungal pneumonia. Outcome was favorable in all cases.
authors.affiliation: Department of Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Marañón, University of Madrid, 28007 Madrid, Spain. pmunoz@micro.hggm.es
authors.forename: Patricia
authors.initials: P
authors.lastname: Muñoz
authors.forename: Maddalena
authors.initials: M
authors.lastname: Giannella
authors.forename: Maricela
authors.initials: M
authors.lastname: Valerio
authors.forename: Teresa
authors.initials: T
authors.lastname: Soria
authors.forename: Fernando
authors.initials: F
authors.lastname: Díaz
authors.forename: Javier Lopez
authors.initials: JL
authors.lastname: Longo
authors.forename: Emilio
authors.initials: E
authors.lastname: Bouza
mesh_terms: D000368:Aged; D000911:Antibodies, Monoclonal / Q000009:adverse effects* / Q000627:therapeutic use; D018501:Antirheumatic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D001172:Arthritis, Rheumatoid / Q000188:drug therapy* / Q000276:immunology; D005260:Female; D006801:Humans; D016867:Immunocompromised Host; D000069285:Infliximab; D008297:Male; D016919:Meningitis, Cryptococcal / Q000139:chemically induced*; D016896:Treatment Outcome; D014409:Tumor Necrosis Factor-alpha / Q000037:antagonists & inhibitors
chemical_list: D000911:Antibodies, Monoclonal; D018501:Antirheumatic Agents; D014409:Tumor Necrosis Factor-alpha; D000069285:Infliximab