MerTK activation during RPE phagocytosis in vivo requires alphaVbeta5 integrin.
Finnemann
Silvia C
SC
Department of Ophthalmology, Weill Medical College of Cornell University, Box 233, 1300 York Avenue, New York, NY 10021, USA.
Nandrot
Emeline F
EF
D000818:Animals; D002462:Cell Membrane / Q000378:metabolism; D003593:Cytoplasm / Q000378:metabolism; D004789:Enzyme Activation; D016023:Integrins / Q000378:metabolism / Q000502:physiology*; D051379:Mice; D018345:Mice, Knockout; D010587:Phagocytosis; D010857:Pigment Epithelium of Eye / Q000166:cytology*; D011518:Proto-Oncogene Proteins / Q000378:metabolism*; D020794:Receptor Protein-Tyrosine Kinases / Q000378:metabolism*; D019030:Receptors, Vitronectin / Q000378:metabolism / Q000502:physiology*; D012374:Rod Cell Outer Segment / Q000378:metabolism; D015398:Signal Transduction; D000076202:c-Mer Tyrosine Kinase
D016023:Integrins; D011518:Proto-Oncogene Proteins; D019030:Receptors, Vitronectin; C064660:integrin alphaVbeta5; C490767:Mertk protein, mouse; D020794:Receptor Protein-Tyrosine Kinases; D000076202:c-Mer Tyrosine Kinase