title: High-density lipoprotein cholesterol: an emerging target for stroke treatment.
abstract: OBJECTIVE
  This review characterizes the current state of knowledge of high-density lipoprotein (HDL) in relation to stroke.
  
  
  RESULTS
  HDL has anti-atherosclerotic and anti-inflammatory properties and is an important component in atherosclerosis. Serum HDL-cholesterol levels are inversely related to heart disease and stroke risk. There are various established and experimental treatments which can raise serum HDL cholesterol and improve its function.
  
  
  CONCLUSIONS
  HDL is an emerging target for atherosclerotic stroke treatment with the potential to dramatically impact the care of stroke patients.
authors.affiliation: Department of Neurology, University of Southern California, Los Angeles, CA 90033, USA. sanossia@yahoo.com
authors.forename: Nerses
authors.initials: N
authors.lastname: Sanossian
authors.forename: Jeffrey L
authors.initials: JL
authors.lastname: Saver
authors.forename: Mohamad
authors.initials: M
authors.lastname: Navab
authors.forename: Bruce
authors.initials: B
authors.lastname: Ovbiagele
mesh_terms: D008076:Cholesterol, HDL / Q000097:blood*; D016503:Drug Delivery Systems / Q000379:methods*; D006801:Humans; D000960:Hypolipidemic Agents / Q000008:administration & dosage*; D020521:Stroke / Q000097:blood* / Q000188:drug therapy
chemical_list: D008076:Cholesterol, HDL; D000960:Hypolipidemic Agents