Healthy Twin: a twin-family study of Korea--protocols and current status.
"Healthy Twin" is a twin family study extension of the existing Korean Twin-Family Register. Healthy Twin recruits adult like-sex twins over the age of 30 and their adult family members. Healthy Twin protocols are primarily tailored to the study of the quantitative trait loci of complex traits as well as to the role of environment in the etiology of complex diseases. A full-length survey is underway, including questionnaires, health examinations and the collection of biological specimens. So far, 820 individuals (169 twin pairs and their families) have participated in the survey and 1068 individual twins (608 twin pairs) have replied to the mailed zygosity questionnaire as of July 2006. The first phase (2005-2006) of Healthy Twin will recruit 1550 individuals (including about 380 twin pairs), and the second phase a proposed 1500 to 2500 additional participants. We report study protocols and zygosity and the distribution of family size of the study participants.
Sung
Joohon
J
Department of Preventive Medicine, Kangwon National University College of Medicine, Korea.
Cho
Sung-Il
SI
Lee
Kayoung
K
Ha
Mina
M
Choi
Eun-Young
EY
Choi
Ji-Sook
JS
Kim
Ho
H
Kim
Jihae
J
Hong
Kyoung Sue
KS
Kim
Yeonju
Y
Yoo
Keun-Young
KY
Park
Chan
C
Song
Yun-Mi
YM
D000328:Adult; D005260:Female; D006801:Humans; D007723:Korea; D008297:Male; D012042:Registries; D018401:Sample Size; D018433:Twin Studies as Topic / Q000941:ethics / Q000379:methods / Q000706:statistics & numerical data; D014429:Twins, Dizygotic; D014430:Twins, Monozygotic