title: Cognate chemokine receptor 1 messenger ribonucleic acid expression in peripheral blood as a diagnostic test for endometriosis.
abstract: We investigated the expression of the cognate chemokine receptor 1 (CCR1) messenger ribonucleic acid, a G-protein-coupled cognate chemokine receptor with high affinity for RANTES (Regulated upon Activation, Normal T cells Expressed and Secreted), in peripheral blood leukocytes of women with and without endometriosis, and its potential use as a diagnostic test for endometriosis. Because patients with an earlier diagnosis of this disease have a better treatment outcome and a reduced recurrence rate, CCR1 mRNA measurement in the peripheral blood of patients with suspected endometriosis might give us a new perspective in diagnosing and treating this disease earlier and better.
authors.forename: Admir
authors.initials: A
authors.lastname: Agic
authors.forename: Hong
authors.initials: H
authors.lastname: Xu
authors.forename: Mirka
authors.initials: M
authors.lastname: Rehbein
authors.forename: Monika M
authors.initials: MM
authors.lastname: Wolfler
authors.forename: Andreas D
authors.initials: AD
authors.lastname: Ebert
authors.forename: Daniela
authors.initials: D
authors.lastname: Hornung
mesh_terms: D018394:CA-125 Antigen / Q000097:blood; D004715:Endometriosis / Q000097:blood / Q000175:diagnosis*; D005260:Female; D006801:Humans; D007962:Leukocytes / Q000378:metabolism*; D011247:Pregnancy; D012333:RNA, Messenger / Q000097:blood*; D054389:Receptors, CCR1; D019707:Receptors, Chemokine / Q000235:genetics*; D012680:Sensitivity and Specificity
chemical_list: D018394:CA-125 Antigen; C515300:CCR1 protein, human; D012333:RNA, Messenger; D054389:Receptors, CCR1; D019707:Receptors, Chemokine