title: [Current status of heredity role in development of allergies among the children].
abstract: The study of the role of compromised allergic heredity among the patients' parents in frequency of allergic illnesses among the children was conducted. Through the accurate analysis were selected two groups of patients. The first group - different allergic diseases (345 sick children from 0 to 17 years old); the second (control) group - different somatic diseases of non-allergic genesis (251 patients of the same age without any records in the anamnesis on development of allergy and signs of accompanied allergic pathologies during the examination period and clinical medication for somatic illnesses of non-allergic genesis. The study of allergic and family anamnesis of patients in both groups-right immediately during the clinical research and therapy, and the retrospective specification of required data via different source of communication certain regularity was revealed that allowed to conclude that among the risk factors that define formation of allergic disposition among the children, the hereditary compromised patients' parents take an important role in development of so called biological defects among their children in pre-natal period of life. These so-called biological defects provide formation and development of allergic status and different allergic diseases among the posterity (risk factor coefficient PR is 2,49 and waves from 1,8 up to 2,73).
authors.affiliation: Tbilisi State Medical University, Department of Medicine.
authors.forename: V
authors.initials: V
authors.lastname: Saakadze
authors.forename: M
authors.initials: M
authors.lastname: Metreveli
mesh_terms: D002648:Child; D004781:Environmental Exposure / Q000009:adverse effects*; D004787:Environmental Pollution / Q000009:adverse effects*; D006801:Humans; D006967:Hypersensitivity / Q000453:epidemiology / Q000209:etiology* / Q000235:genetics*; D015995:Prevalence