Sporicidal Activity of the KMT reagent in its vapor phase against Geobacillus stearothermophilus Spores.
In an investigation of the sporicidal activity of the KMT reagent, a vapor phase study was performed using five kinds of carriers contaminated with Geobacillus stearothermophilus spores. When 25 ml of the KMT reagent was vaporized in a chamber (capacity; approximately 95 liters), the 2-step heating method (vaporization by a combination of low temperature and high temperature) showed the most effective sporicidal activity in comparison with the 1-step heating method (rapid vaporization). The 2-step heating method appeared to be related to the sporicidal activity of vaporized KMT reagent, i.e., ethanol and iodine, which vaporized mainly when heated at a low temperature such as 55 C, and acidic water, which vaporized mainly when heated at a high temperature such as 300 C. We proposed that the KMT reagent can be used as a new disinfectant not only in the liquid phase but also in the vapor phase in the same way as peracetic acid and hydrogen peroxide.
Kida
Nori
N
Niigata Quarantine Station, Ministry of Health, Labour and Welfare, Japan. kida-nori@keneki.go.jp
Mochizuki
Yasushi
Y
Taguchi
Fumiaki
F
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001406:Bacillaceae / Q000187:drug effects*; D004203:Disinfection / Q000379:methods; D050296:Microbial Viability / Q000187:drug effects*; D013171:Spores, Bacterial / Q000187:drug effects*; D014835:Volatilization
D000900:Anti-Bacterial Agents