Field trial for the control of zoonotic cutaneous leishmaniosis in Badrood, Iran.
BACKGROUND
Due to the resurgence of zoonotic cutaneous leishmaniosis (ZCL) in some nonendemic areas of Iran, extensive studies have been conducted on the epidemiology of the disease in different parts of the country in recent years. The objective of this study was to determine the effects of rodent control on the reduction of the incidence of ZCL in an endemic area in Badrood, Iran.


METHODS
A survey was carried out in a circle around two villages between April 1997 and January 1999. The control strategy adopted in 1997 consisted of the destruction of the colonies of gerbilline rodents by digging in a radius of 500 m from houses in the intervention area. Opened burrows were baited with zinc phosphide. One village was used as control. Evaluation was made in 1998 and no other control measures were carried out in the area. Case findings were done by house-to-house visits once every season during 1997 and 1998, and all the inhabitants of the selected villages were examined.


RESULTS
The average reduction of rodent holes was calculated at 87.4% one year after the first baiting in the intervention area. Changes in the number of rodent holes and the incidence of the disease in the intervention and control villages were statistically significant (P-value <0.000001).


CONCLUSIONS
Our evaluation demonstrated that the control program reduced the incidence of ZCL 12-fold in the treated village compared to the control at the end of the first year of operation, and to more than one-fifth of its original level after two years. The results show that the field control method is very effective in destroying rodents and reducing the incidence of ZCL on a small scale and in special circumstances.
Yaghoobi-Ershadi
M R
MR
School of Public Health and Institute of Public Health Research, Tehran University of Medical Sciences, Tehran, Iran. rezatr12@yahoo.com
Akhavan
A A
AA
Zahraei-Ramazani
A R
AR
Javadian
E
E
Motavalli-Emami
M
M