title: An efficient one-pot asymmetric synthesis of biaryl compounds via Diels-Alder/retro-Diels-Alder cascade reactions.
abstract: [reaction: see text] A single-step chirality transfer method for the synthesis of axially chiral biaryl compounds by construction of the second aromatic ring via a Diels-Alder/retro-Diels-Alder cascade reaction is reported. This methodology should find broad application in the synthesis of natural products and asymmetric catalysts.
authors.affiliation: Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education and Beijing National Laboratory for Molecular Science (BNLMS), College of Chemistry, Laboratory of Chemical Genomics, Shenzhen Graduate School, China.
authors.forename: Yongxiang
authors.initials: Y
authors.lastname: Liu
authors.forename: Kui
authors.initials: K
authors.lastname: Lu
authors.forename: Mingji
authors.initials: M
authors.lastname: Dai
authors.forename: Kai
authors.initials: K
authors.lastname: Wang
authors.forename: Wanqing
authors.initials: W
authors.lastname: Wu
authors.forename: Jiahua
authors.initials: J
authors.lastname: Chen
authors.forename: Junmin
authors.initials: J
authors.lastname: Quan
authors.forename: Zhen
authors.initials: Z
authors.lastname: Yang
mesh_terms: D008958:Models, Molecular; D015394:Molecular Structure; D009930:Organic Chemicals / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D009930:Organic Chemicals