[Pulmonary nodular amyloidosis].
Amyloidosis is a systemic disease caused by extracellular accumulation of amyloid in different parts of the body. Pulmonary involvement is infrequent and nodular amyloidosis is extremely rare. We present the case of a 72-year-old man with chronic obstructive pulmonary disease in whom a 3-cm pulmonary nodule was discovered during routine radiological follow-up. After various complementary investigations failed to identify the etiology of the nodule, surgical excision was performed. Subsequent histopathological study revealed the presence of amyloid deposits with characteristic apple-green birefringence when stained with Congo-red under polarized light microscopy.
Esteban
Marcos Bruna
MB
Servicio de Cirugía General y del Aparato Digestivo, Servicio de Cirugía Torácica, Consorcio Hospital General Universitario de Valencia, Valencia, España. drbruna@comv.es
Obrer
Antonio Arnau
AA
Martínez
Antonio Honguero
AH
Guerrero
Míriam Estors
ME
Armengod
Antonio Cantó
AC
D000368:Aged; D000686:Amyloidosis / Q000175:diagnosis; D017809:Fatal Outcome; D006801:Humans; D008171:Lung Diseases / Q000175:diagnosis; D008297:Male