Obesity and the kidney: why is the kidney at risk?
Two recent studies may help to account for the increase in risk of renal injury associated with obesity. One study pointed to a role for renin-system activation. In the other study, the pattern of renal hemodynamics was compatible with a renin mechanism.
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Department of Medicine, Harvard Medical School and Brigham and Women's Hospital, Boston, Massachusetts 02115, USA. djpagecapo@rics.bwh.harvard.edu
D015992:Body Mass Index; D006801:Humans; D007668:Kidney / Q000098:blood supply* / Q000502:physiology; D007674:Kidney Diseases / Q000209:etiology*; D009765:Obesity / Q000150:complications*; D017595:Renal Plasma Flow; D012084:Renin-Angiotensin System / Q000502:physiology*; D012306:Risk