Investigation of the Anti-Snake Venom Activity of Schumanniophyton magnificum.
Polar fractions of the methanolic extracts of the stem- and root-barks of SCHUMANNIOPHYTON MAGNIFICUM (Rubiaceae) reduced the effects of cobra venom cardiotoxin in the chick biventer cervicis nerve-muscle preparation IN VITRO. No activity was observed against a curaremimetic neurotoxin from cobra venom. Further fractionation of the extracts showed that the activity was not due to alkaloidal components, but the active substances could not be identified or isolated.
Houghton
P J
PJ
Pharmacognosy Research Laboratories, Chelsea Department of Pharmacy, King's College London (KQC), Manresa Rd, London SW3 6LX, U.K.
Harvey
A L
AL