title: Antioxidant and lipophilic constituents of Tinospora crispa.
abstract: TLC autographic assays revealed in the CH(2)Cl(2) extract of Tinospora crispa Miers (Menispermaceae) the presence of three compounds exhibiting antioxidant and radical scavenging properties towards beta-carotene and 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical. They were isolated and identified as N-CIS-feruloyltyramine, N-trans-feruloyltyramine and secoisolariciresinol. When tested in dilution assays on the reduction of the DPPH radical, these 3 compounds proved to be more active than the synthetic antioxidant butylhydroxytoluene (BHT). Further investigation of the CH(2)Cl(2) extract led to the isolation of vanillin, syringin, the alkaloid N-formylnornuciferin and the diterpene derivatives borapetosides B and C. In addition, a LC/UV/MS analysis enabled the on-line identification of borapetoside F and N-formylannonain.
authors.affiliation: Institut de Pharmacognosie et Phytochimie, Université de Lausanne, Lausanne, Switzerland.
authors.forename: A
authors.initials: A
authors.lastname: Cavin
authors.forename: K
authors.initials: K
authors.lastname: Hostettmann
authors.forename: W
authors.initials: W
authors.lastname: Dyatmyko
authors.forename: O
authors.initials: O
authors.lastname: Potterat