title: Post-traumatic spontaneous recurrent hypothermia: a variant of Shapiro's syndrome.
abstract: A 49-year-old man presented with episodic hypothermia many years after sustaining a contusional brain injury. Brain magnetic resonance imaging demonstrated the destruction of the anterior parts of the corpus callosum without hypothalamic lesions. Nevertheless, delayed hypothalamic dysfunction at the neurotransmitter level is the probable pathophysiological key factor. Clomipramine treatment was beneficial. This case expands the spectrum of Shapiro's syndrome.
authors.affiliation: Department of Neurology, Ghent University Hospital, Ghent, Belgium. dimitri.hemelsoet@ugent.be
authors.forename: D M
authors.initials: DM
authors.lastname: Hemelsoet
authors.forename: J L
authors.initials: JL
authors.lastname: De Bleecker
mesh_terms: D001831:Body Temperature / Q000187:drug effects; D001930:Brain Injuries / Q000150:complications* / Q000175:diagnosis; D002997:Clomipramine / Q000627:therapeutic use; D003337:Corpus Callosum / Q000473:pathology; D006801:Humans; D007035:Hypothermia / Q000188:drug therapy / Q000209:etiology* / Q000503:physiopathology; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D013577:Syndrome
chemical_list: D002997:Clomipramine