Clinical management of diabetic foot infection: diagnostics, therapeutics and the future.
Diabetic foot infection accounts for a substantial global burden of morbidity, psychosocial disruption and economic cost. Recommendations for best practice are continuously evolving in parallel with improvements in imaging modalities, development and clinical use of new antimicrobial agents and data surrounding novel adjunctive strategies. We discuss this complex group of infections with a particular emphasis on medical management of osteomyelitis, while also highlighting the importance of a broad multidisciplinary approach to eradicating infection.
Matthews
Philippa C
PC
Bone Infection Unit, Nuffield Orthopaedic Centre NHS Trust, Windmill Road, Headington, Oxford OX3 7LD, UK. p.matthews@doctors.org.uk
Berendt
Anthony R
AR
Lipsky
Benjamin A
BA
D048909:Diabetes Complications / Q000175:diagnosis / Q000191:economics / Q000382:microbiology / Q000628:therapy; D003920:Diabetes Mellitus / Q000175:diagnosis* / Q000191:economics / Q000382:microbiology / Q000628:therapy*; D017719:Diabetic Foot / Q000175:diagnosis* / Q000191:economics / Q000382:microbiology / Q000628:therapy*; D005544:Forecasting; D006801:Humans; D013203:Staphylococcal Infections / Q000175:diagnosis / Q000191:economics / Q000382:microbiology / Q000628:therapy