title: Randomized prospective study comparing tri-cortical iliac crest autograft to allograft in the lateral column lengthening component for operative correction of adult acquired flatfoot deformity.
abstract: BACKGROUND
  Operative treatment of stage II posterior tibial tendon insufficiency (PTTI) is controversial. Many soft-tissue and bony procedures and various combinations of the two have been reported for treatment of stage II PTTI. Orthopaedists recognize the lateral column lengthening component of the procedure as a successful reconstructive technique. The use of cortical allograft for lateral column lengthening in the correction of pes planus in the pediatric patient population has been routine. In the adult population, however, tricortical iliac crest autograft has been the bone graft of choice. Harvest of this autograft can precipitate significant morbidity and cost. Therefore, we undertook this randomized controlled trial to compare graft incorporation and healing of allograft and autograft in the lateral column lengthening component of adult flatfoot reconstruction.
  
  
  METHODS
  Lateral column lengthening was done as a component of operative correction for stage II PTTI in adult patients (older than 18 years) by two surgeons using similar procedures. The patients were randomized to either the allograft or autograft procedures. The primary endpoint was graft incorporation and healing as assessed by radiographs.
  
  
  RESULTS
  The study included 33 randomized feet in 31 patients. We followed 18 feet in the allograft group and 15 in the autograft group to the point of union. There were 21 women and 10 men. There were no delayed unions, nonunions, or hardware failures. All patients in both groups achieved bony union by the 12-week followup evaluation. Two superficial foot infections were successfully treated with oral antibiotics. Two patients in the autograft group continued to have hip donor site pain at 3 months.
  
  
  CONCLUSIONS
  This study suggests that union rates of allograft and autograft (iliac crest bone graft) are equal. The use of allograft in the lateral column lengthening component of operative correction of adult stage II PTTI appears to be a viable alternative to the use of iliac crest autograft and eliminates the morbidity and increased cost associated with autograft harvest.
authors.affiliation: Grand Rapids Medical Education and Research Center, Michigan State University, School of Medicine, 2319 Burchard Street SE, Grand Rapids, MI 49506, USA. cmdolan@ucdavis-alumni.com
authors.forename: Christopher M
authors.initials: CM
authors.lastname: Dolan
authors.forename: Jeffrey A
authors.initials: JA
authors.lastname: Henning
authors.forename: John G
authors.initials: JG
authors.lastname: Anderson
authors.forename: Donald R
authors.initials: DR
authors.lastname: Bohay
authors.forename: Marc J
authors.initials: MJ
authors.lastname: Kornmesser
authors.forename: Terrence J
authors.initials: TJ
authors.lastname: Endres
mesh_terms: D000328:Adult; D000368:Aged; D016025:Bone Transplantation / Q000379:methods*; D005260:Female; D005413:Flatfoot / Q000601:surgery*; D005529:Foot Bones / Q000601:surgery*; D005531:Foot Deformities, Acquired; D006801:Humans; D007085:Ilium / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D014182:Transplantation, Autologous; D014184:Transplantation, Homologous; D016896:Treatment Outcome