Assessment of acute reperfused myocardial infarction with delayed enhancement 64-MDCT.
OBJECTIVE
The purpose of this study was to evaluate the utility of delayed enhancement 64-MDCT in the assessment of myocardial infarct size in a porcine model of acute reperfused myocardial infarction. CT can be used for noninvasive assessment of coronary artery stenosis, but to our knowledge, evaluation of myocardial viability in the subacute phase of acute myocardial infarction has not been validated. We performed delayed enhancement imaging on six domestic swine 5 days after reperfused acute myocardial infarction and assessed the relation between delayed enhancement patterns in vivo and the extent of viable and nonviable myocardium at postmortem histochemical analysis.


CONCLUSIONS
Delayed enhancement imaging with 64-MDCT can be used for accurate assessment of the size of reperfused acute myocardial infarcts.
Baks
Timo
T
Department of Cardiology, Erasmus Medical Center, Dr. Molewaterplein 40, Rotterdam, The Netherlands. t.baks@erasmusmc.nl
Cademartiri
Filippo
F
Moelker
Amber D
AD
van der Giessen
Willem J
WJ
Krestin
Gabriel P
GP
Duncker
Dirk J
DJ
de Feyter
Pim J
PJ
D000818:Animals; D005240:Feasibility Studies; D009203:Myocardial Infarction / Q000000981:diagnostic imaging* / Q000209:etiology; D015428:Myocardial Reperfusion Injury / Q000150:complications / Q000000981:diagnostic imaging*; D017682:Myocardial Stunning / Q000000981:diagnostic imaging* / Q000209:etiology; D011856:Radiographic Image Enhancement / Q000295:instrumentation / Q000379:methods*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013552:Swine; D013997:Time Factors; D014057:Tomography, X-Ray Computed / Q000295:instrumentation / Q000379:methods*