title: Solitary osseous plasmacytoma of the orbit with amyloidosis.
abstract: A 40-year-old woman with an orbital lesion presented with a history of slowly progressive proptosis. A thorough systemic workup did not reveal any stigmata of multiple myeloma, and she was treated with a course of orbital radiotherapy. Histopathologic studies of the biopsy specimen revealed a proliferation of neoplastic plasma cells, which produced monoclonal lambda light chains surrounding concretions of congophilic, amorphous material. The lesion was diagnosed as a solitary osseous plasmacytoma of the orbit containing amyloid.
authors.affiliation: Department of Ophthalmology, University of Ottawa Eye Institute, The Ottawa Hospital, Ottawa, Ontario, Canada.
authors.forename: Nigel G
authors.initials: NG
authors.lastname: Rawlings
authors.forename: Seymour
authors.initials: S
authors.lastname: Brownstein
authors.forename: Jennifer W
authors.initials: JW
authors.lastname: Robinson
authors.forename: David R
authors.initials: DR
authors.lastname: Jordan
mesh_terms: D000328:Adult; D000682:Amyloid / Q000378:metabolism; D000686:Amyloidosis / Q000000981:diagnostic imaging / Q000378:metabolism / Q000473:pathology*; D005260:Female; D006801:Humans; D009918:Orbital Neoplasms / Q000000981:diagnostic imaging / Q000378:metabolism / Q000473:pathology*; D010954:Plasmacytoma / Q000000981:diagnostic imaging / Q000378:metabolism / Q000473:pathology*; D014057:Tomography, X-Ray Computed
chemical_list: D000682:Amyloid