title: Localizing and lateralizing value of behavioral change in childhood partial seizures.
abstract: OBJECTIVE
  To describe clinical characteristics as well as localizing and lateralizing value of behavioral change (BC) at the onset of childhood seizures.
  
  
  METHODS
  Five hundred forty-one videotaped seizures of 109 consecutive patients < or = 12 years with partial epilepsy and postoperatively seizure-free outcome were analyzed. Behavioral change (the first clinical feature of a certain seizure with a sudden change in the child's behavior) was evaluated by two independent investigators.
  
  
  RESULTS
  Thirty-three (30%) patients showed BC at least once during their seizures. Behavioral changes appeared in arrestive form in 19 and with affective activities in 18 children; four patients produced both kinds of BCs, separately. Arrest-type BC happened in 16 of 50 children with right- and 3 of 59 patients with left-sided seizure onset zone (p < 0.001). Affective-type BC was observed in 17 of 67 temporal lobe epilepsy patients while it happened in only 1 of 42 children with extratemporal lobe epilepsy (p = 0.001).
  
  
  CONCLUSIONS
  Arrest-type BC lateralizes to the right hemisphere, while affective-type BC localizes to the temporal lobe in childhood partial seizures. Type of BCs can add important information to the presurgical evaluation of young children with refractory partial epilepsy.
authors.affiliation: Epilepsie-Zentrum Bethel, Bielefeld, Germany.
authors.forename: András
authors.initials: A
authors.lastname: Fogarasi
authors.forename: József
authors.initials: J
authors.lastname: Janszky
authors.forename: Ingrid
authors.initials: I
authors.lastname: Tuxhorn
mesh_terms: D017677:Age Distribution; D000367:Age Factors; D001931:Brain Mapping; D002540:Cerebral Cortex / Q000503:physiopathology*; D002648:Child; D002652:Child Behavior / Q000502:physiology; D002675:Child, Preschool; D018572:Disease-Free Survival; D004828:Epilepsies, Partial / Q000175:diagnosis* / Q000503:physiopathology* / Q000601:surgery; D004833:Epilepsy, Temporal Lobe / Q000175:diagnosis / Q000503:physiopathology / Q000601:surgery; D005260:Female; D007839:Functional Laterality / Q000502:physiology*; D006801:Humans; D007223:Infant; D018730:Infant Behavior / Q000502:physiology; D008297:Male; D009043:Motor Activity / Q000502:physiology; D011300:Preoperative Care; D014743:Videotape Recording