[CT diagnosis and pathological findings of testicular lesion].
OBJECTIVE
To investigate the value of CT scan in the diagnosis and differential diagnosis of testicular space-occupying lesions.


METHODS
In patients with testicular space-occupying lesions, 11 underwent examinations for such tumor markers as alpha-fetoprotein (AFP) and human chorionic gonadotropin (HCG). Plain CT scans were performed with a section thickness and interval of 2 mm followed by enhanced scans after intravenous bolus injection of 70 ml 60% ultravist. Spiral CT multiplanar reconstruction images were also obtained.


RESULTS
Of the 13 patients, histopathologically confirmed seminoma was found in 3, endodermal sinus tumor in 1, teratoma in 2, mixed germinoma in 2, leucoma in 1 case, abscess in 2, and tuberculosis in 2. One seminoma patient had slightly elevated AFP level while 5 of the 6 noneminoma patients (83%) had elevated AFP level. CT scans displayed characteristic features for diagnosis of testicular space-occupying lesions. Spiral CT with multiplanar reconstruction allowed full view of the lesions and demonstrated their relationship with the surrounding structures.


CONCLUSIONS
CT scan in combination with the clinical analysis and tumor marker examinations can be of important value in the diagnosis and differential diagnosis of testicular space-occupying lesions. The application of spiral CT multiplanar reconstruction also helps in the diagnosis.
Duan
Gang
G
Diagnostic Imaging Center, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China. dr.duan@163.com
Xu
Yi-Kai
YK
Dai
Lin
L
Zhang
Xiao-Dong
XD
D000328:Adult; D014408:Biomarkers, Tumor / Q000032:analysis; D006063:Chorionic Gonadotropin / Q000032:analysis; D006651:Histocytochemistry; D006801:Humans; D008297:Male; D015203:Reproducibility of Results; D018239:Seminoma / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000378:metabolism; D012680:Sensitivity and Specificity; D013733:Testicular Diseases / Q000175:diagnosis* / Q000378:metabolism; D013736:Testicular Neoplasms / Q000175:diagnosis* / Q000378:metabolism; D013737:Testis / Q000737:chemistry / Q000000981:diagnostic imaging / Q000473:pathology*; D014057:Tomography, X-Ray Computed / Q000379:methods*; D000509:alpha-Fetoproteins / Q000032:analysis
D014408:Biomarkers, Tumor; D006063:Chorionic Gonadotropin; D000509:alpha-Fetoproteins