title: [Chemical constituents from red alga Corallina pilulifera].
abstract: OBJECTIVE
  To investigate the chemical constituents of red alga Corallina pilulifera.
  
  
  METHODS
  Compounds were isolated by normal phase silica gel and Sephadex LH - 20 gel column chromatography, reverse phase HPLC and recrystallization. Their structures were elucidated by spectroscopic methods including MS, 1H-NMR, 13C-NMR, HSQC, HMBC. Cytotoxicity of the compounds was screened by using standard MTT method.
  
  
  RESULTS
  Seven compounds were isolated from red alga C. pilulifera, their structures were identified as (E) -phytol epoxide (1), phytenal (2), phytol (3), dehydrovomifoliol (4), loliolide (5), 3beta-hydroxy-5alpha, 6alpha-epoxy-7-megastigmene-9-one (6), 4-hydroxybenzaldehyde (7).
  
  
  CONCLUSIONS
  All of the compounds were obtained from this species for the first time. These compounds were inactive (IC50 > 10 microg x mL(-1)) in the MTT assay.
authors.affiliation: Institute of Oceanology, Chinese Academy of Sciences, Qingdao 266071, China.
authors.forename: Zhao-Hui
authors.initials: ZH
authors.lastname: Yuan
authors.forename: Li-Jun
authors.initials: LJ
authors.lastname: Han
authors.forename: Xiao
authors.initials: X
authors.lastname: Fan
authors.forename: Shuai
authors.initials: S
authors.lastname: Li
authors.forename: Da-Yong
authors.initials: DY
authors.lastname: Shi
authors.forename: Jie
authors.initials: J
authors.lastname: Sun
authors.forename: Ming
authors.initials: M
authors.lastname: Ma
authors.forename: Yong-Chun
authors.initials: YC
authors.lastname: Yang
authors.forename: Jian-Gong
authors.initials: JG
authors.lastname: Shi
mesh_terms: D001547:Benzaldehydes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D001572:Benzofurans / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D045744:Cell Line, Tumor / Q000187:drug effects; D006801:Humans; D010836:Phytol / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D000461:Rhodophyta / Q000737:chemistry*
chemical_list: D001547:Benzaldehydes; D001572:Benzofurans; D010836:Phytol; C011483:4-hydroxybenzaldehyde; C030425:loliolide