title: Iodine nutrition status of exclusively breast-fed infants and their mothers in New Delhi, India.
abstract: OBJECTIVE
  To assess the iodine nutrition status of exclusively breast-fed infants and their mothers.
  
  
  OBJECTIVE
  In the presence of environmental and maternal iodine deficiency, an exclusively breast-fed baby is likely to receive a suboptimal iodine supply during the period of rapid brain growth.
  
  
  METHODS
  Spot urinary iodine (UI) and serum TSH levels were measured in 175 healthy, exclusively breast-fed infants and their mothers. Iodine content of salt used by participants for domestic consumption was also analyzed.
  
  
  RESULTS
  The median UI levels in mothers and infants was 124 microg/l and 162 microg/l, respectively. 34% of mothers and 21% of infants had UI levels <100 microg/l indicating iodine deficiency. Serum TSH was elevated in 29% of mothers and 2% of infants. No correlation was observed between individual mother-infant UI or serum TSH levels (r = -0.036, r = -0.1 for UI excretion and serum TSH, respectively). 96% of the salt samples tested had adequate iodine concentration, i.e. >15 ppm.
  
  
  CONCLUSIONS
  The present study demonstrated significant iodine deficiency in both mothers and infants despite consumption of adequately iodized salt. The iodine nutrition status of the infants was better compared to the mothers, indicating a preferential iodine supply to the infants over the mothers.
authors.affiliation: Department of Pediatrics, Lady Hardinge Medical College and Kalawati Saran Children's Hospital.
authors.forename: Rishi
authors.initials: R
authors.lastname: Gupta
authors.forename: Anju
authors.initials: A
authors.lastname: Seth
authors.forename: C S
authors.initials: CS
authors.lastname: Pandav
authors.forename: M G
authors.initials: MG
authors.lastname: Karmarkar
authors.forename: S
authors.initials: S
authors.lastname: Aneja
mesh_terms: D000293:Adolescent; D000328:Adult; D001942:Breast Feeding; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D007194:India; D007223:Infant; D007231:Infant, Newborn / Q000097:blood; D007455:Iodine / Q000172:deficiency* / Q000652:urine; D007774:Lactation / Q000097:blood / Q000378:metabolism* / Q000652:urine; D008297:Male; D039382:Maternal Nutritional Physiological Phenomena; D009752:Nutritional Status; D013961:Thyroid Gland / Q000502:physiology; D013972:Thyrotropin / Q000097:blood
chemical_list: D013972:Thyrotropin; D007455:Iodine