More promiscuity resulting in more tolerance.
Tolerance to self is engendered by multiple mechanisms. Lymph node stromal cells are now found to contribute to self-tolerance by their endogenous expression of peripheral tissue antigens.
Zehn
Dietmar
D
Bevan
Michael J
MJ
D000818:Animals; D000941:Antigens / Q000276:immunology; D006801:Humans; D007108:Immune Tolerance / Q000276:immunology*; D008198:Lymph Nodes / Q000276:immunology; D017154:Stromal Cells / Q000276:immunology; D013601:T-Lymphocytes / Q000276:immunology
D000941:Antigens