Early restenosis after drug-eluting stent implantation: A putative role for platelet activation.
Drug-eluting stents (DES) reduce intimal hyperplasia and restenosis, but they also inhibit stent endothelization, making the vascular surface more thrombogenic. The present report describes two cases of in-stent restenosis after DES deployment at exactly the same sites where subacute stent thrombosis had occurred. Extremely careful follow-up is mandatory after the recognition of intraluminal thrombi inside DES because restenosis may occur at the same site of DES thrombosis.
Tamburino
Corrado
C
Institute of Cardiology, Ferrarotto Hospital, University of Catania, Italy.
Ussia
Gian Paolo
GP
Zimarino
Marco
M
Galassi
Alfredo R
AR
De Caterina
Raffaele
R
D000368:Aged; D015906:Angioplasty, Balloon, Coronary; D019917:Blood Vessel Prosthesis Implantation / Q000009:adverse effects; D023903:Coronary Restenosis / Q000209:etiology / Q000503:physiopathology*; D016503:Drug Delivery Systems; D016903:Drug Monitoring; D004730:Endothelium, Vascular / Q000187:drug effects / Q000473:pathology*; D005260:Female; D006801:Humans; D008297:Male; D015539:Platelet Activation / Q000187:drug effects; D018570:Risk Assessment; D012307:Risk Factors; D015607:Stents / Q000009:adverse effects*; D013997:Time Factors