Recurrent acute hepatitis in patient receiving pulsed methylprednisolone for multiple sclerosis.
We report clinically significant, recurrent acute hepatitis in a 48-year-old woman receiving pulsed treatment with methylprednisolone for multiple sclerosis. No other cause was found for the episodes and the temporal and histological correlations were consistent with immune-allergic type drug-induced hepatitis.
Das
Debasish
D
Directorate of Medicine, The Ayr Hospital, Dalmellington Road, Ayr KA6 6AF, Scotland. debasishdas@doctors.org.uk
Graham
Iain
I
Rose
James
J
D000208:Acute Disease; D056486:Chemical and Drug Induced Liver Injury / Q000175:diagnosis / Q000276:immunology*; D004342:Drug Hypersensitivity / Q000175:diagnosis*; D005260:Female; D005938:Glucocorticoids / Q000009:adverse effects*; D006801:Humans; D008099:Liver / Q000473:pathology; D008775:Methylprednisolone / Q000009:adverse effects*; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000188:drug therapy*; D012008:Recurrence
D005938:Glucocorticoids; D008775:Methylprednisolone