title: [Accelerated fatigue test in vitro of expanded polytetrafluoroethylene artificial heart valve].
abstract: OBJECTIVE
  To study the durability of expanded polytetrafluoroethylene artificial heart valve (ePTFE AHV).
  
  
  METHODS
  Six ePTFE AHVs were tested for 400 million times against accelerated fatigue using TH-2200 artificial heart valve exosomatic accelerated fatigue instrument. Hydromechanical parameters of fore-and-aft accelerated fatigue test of the 6 AHVs were obtained by TH-1200 artificial heart valve exosomatic pulsatile stream instrument.
  
  
  CONCLUSIONS
  The mean gradient pressure spanning the valve and the effective orific area of ePTFE AHVs did not undergo significant changes after fore-and-aft the fatigue test, but the regurgitation volume and regurgitation rate of ePTFE AHVs were reduced after the accelerated fatigue test, suggesting good durability of ePTFE AHV.
authors.affiliation: Department of Cardiothoracic Surgery, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
authors.forename: Hai-bo
authors.initials: HB
authors.lastname: Li
authors.forename: Wu-jun
authors.initials: WJ
authors.lastname: Wang
authors.forename: Yong
authors.initials: Y
authors.lastname: Liang
authors.forename: Kai-can
authors.initials: KC
authors.lastname: Cai
authors.forename: Xiao-ming
authors.initials: XM
authors.lastname: Zou
authors.forename: Zhen-Kang
authors.initials: ZK
authors.lastname: Wang
mesh_terms: D001672:Biocompatible Materials / Q000737:chemistry*; D006350:Heart Valve Prosthesis / Q000592:standards*; D008422:Materials Testing / Q000379:methods*; D011138:Polytetrafluoroethylene / Q000737:chemistry*; D013718:Tensile Strength
chemical_list: D001672:Biocompatible Materials; D011138:Polytetrafluoroethylene