A highly diastereoselective, catalytic three-component assembly reaction for the synthesis of spiropyrrolidinyloxindoles.
Spiropyrrolidinyloxindole compounds are synthesized in moderate to excellent yield via a highly diastereoselective Cu(I)-catalysed three-component assembly reaction of an imine, diazo-compound and substituted olefin dipolarophile.
Galliford
Chris V
CV
Department of Chemistry, Northwestern University, 2145 Sheridan Road, Evanston, IL 60208, USA.
Martenson
James S
JS
Stern
Charlotte
C
Scheidt
Karl A
KA