Disseminated haemangioblastoma without evidence of the von Hippel-Lindau syndrome or haemangioblastomatosis--A case report and clinico-pathological correlation.
A 71-year-old Caucasian female presented to our service with disseminated cranial and spinal haemangioblastomata but no other features to suggest the von Hippel-Lindau syndrome. We feel that this represents cellular dissemination through the cerebro-spinal fluid and may be an intermediate step to the development of frank haemangioblastomatosis. By comparing this presentation to that of other tumours we have suggested a potential pathological mechanism and have discussed its management.
Lightfoot
Nicholas J
NJ
Department of Neurosurgery, Christchurch Hospital, Private Bag 4710, Christchurch, New Zealand. litefoot@paradise.net.nz
Lucas
Peter G
PG
Finnis
Nicholas D M
ND
D000368:Aged; D001932:Brain Neoplasms / Q000134:cerebrospinal fluid / Q000473:pathology* / Q000601:surgery; D005260:Female; D018325:Hemangioblastoma / Q000134:cerebrospinal fluid / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008279:Magnetic Resonance Imaging; D009361:Neoplasm Invasiveness; D016609:Neoplasms, Second Primary / Q000473:pathology* / Q000601:surgery; D019635:Neurosurgical Procedures; D006623:von Hippel-Lindau Disease / Q000175:diagnosis*