[Delivery room cardiopulmonary resucitation of very preterm infant is associated with adverse short- and long-term outcomes].
OBJECTIVE
To assess the short- and long-term outcome of infants<or=1250 grams who have received delivery room cardiopulmonary resuscitation (DR-CPR).


METHODS
In a cohort of infants<or=1250 grams born between 01/2000 and 12/2003, we compared the rates of death, severe intraventricular hemorrhage (S-IVH), periventricular leukomalacia and combined poor short-term outcome (CO). At 18 months post- conception age (PCA) we compared DR-CPR and non-DR-CPR groups on the Bayley II Mental and Psychomotor Developmental Indices (MDI and PDI).


RESULTS
Of 397 infants who met enrollment criteria, the 53 (13%) who received DR-CPR had a higher risk for mortality, S-IVH, PVL and CO. At 18 months PCA, MDI and PDI scores were lower in the DR-CPR group (67.7+/-18.3 vs. 81.3+/-17.7; p=0.006) and (74.4+/-19.9 vs. 85.1+/-17.2; p=0.027), respectively.


CONCLUSIONS
DR-CPR in infants<1250 grams is associated with higher mortality and greater short- and long-term morbidity.
Deulofeut
R
R
División de Medicina Neonatal-Perinatal, Universidad de Emory, Atlanta, Georgia, and Mid Atlantic Neonatology Associates, Morristown Hospital, NJ, USA. richard_deulofeut@pediatrix.com
Sola
A
A
Lee
B
B
Rogido
M
M
D016887:Cardiopulmonary Resuscitation / Q000009:adverse effects*; D003696:Delivery Rooms; D005260:Female; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D007235:Infant, Premature, Diseases / Q000628:therapy*; D008297:Male; D013997:Time Factors; D016896:Treatment Outcome