title: Psychosis leading to the diagnosis of unrecognized systemic lupus erythematosus: a case report.
abstract: We present the case of a woman whose psychiatric clinical picture was the major manifestation of SLE with unrecognized secondary antiphospholipid syndrome. The atypical onset and the subsequent clinical course of the psychiatric manifestations led to the diagnosis. This case demonstrates the heterogeneous progress of SLE, the increasing relevance of the antiphospholipid antibodies in the central nervous system and the difficulty in making an early diagnosis.
authors.affiliation: Department of Psychiatry, La Princesa University Hospital, Madrid, Spain. vic_fgh@hotmail.com
authors.forename: V
authors.initials: V
authors.lastname: Fernández Ga de Las Heras
authors.forename: M A
authors.initials: MA
authors.lastname: Gorriti
authors.forename: R
authors.initials: R
authors.lastname: García-Vicuña
authors.forename: J L
authors.initials: JL
authors.lastname: Santos Ruiz
mesh_terms: D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D000925:Anticoagulants / Q000627:therapeutic use; D016736:Antiphospholipid Syndrome / Q000150:complications* / Q000276:immunology* / Q000523:psychology; D001323:Autoantibodies / Q000097:blood / Q000276:immunology; D002540:Cerebral Cortex / Q000276:immunology / Q000378:metabolism / Q000473:pathology; D003520:Cyclophosphamide / Q000627:therapeutic use; D003937:Diagnosis, Differential; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008180:Lupus Erythematosus, Systemic / Q000150:complications* / Q000175:diagnosis* / Q000503:physiopathology; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D011237:Predictive Value of Tests; D011618:Psychotic Disorders / Q000276:immunology* / Q000378:metabolism* / Q000503:physiopathology; D016896:Treatment Outcome
chemical_list: D000893:Anti-Inflammatory Agents; D000925:Anticoagulants; D001323:Autoantibodies; D005938:Glucocorticoids; D007166:Immunosuppressive Agents; D003520:Cyclophosphamide