title: Currently available drugs for the treatment of obesity: Sibutramine and orlistat.
abstract: The currently available drugs for long-term treatment of obesity are sibutramine and orlistat. They have been shown to be able to induce significant weight loss, with important co-morbidity reduction, allowing the maintenance of reduced body weight for at least 1-2 years. Cardiostimulating and gastrointestinal adverse effects are however not negligible.
authors.affiliation: Division of Kinesiology (PEPS), Laval University, Sainte-Foy, Québec, Canada, G1K 7P4.
authors.forename: J-P
authors.initials: JP
authors.lastname: Chaput
authors.forename: S
authors.initials: S
authors.lastname: St-Pierre
authors.forename: A
authors.initials: A
authors.lastname: Tremblay
mesh_terms: D019440:Anti-Obesity Agents / Q000009:adverse effects / Q000627:therapeutic use*; D001835:Body Weight; D003503:Cyclobutanes / Q000009:adverse effects / Q000627:therapeutic use*; D004734:Energy Metabolism; D015444:Exercise; D006801:Humans; D007783:Lactones / Q000009:adverse effects / Q000627:therapeutic use*; D009765:Obesity / Q000188:drug therapy*; D000077403:Orlistat
chemical_list: D019440:Anti-Obesity Agents; D003503:Cyclobutanes; D007783:Lactones; D000077403:Orlistat; C058254:sibutramine