title: Characteristic magnetic resonance enhancement pattern in cerebral schistosomiasis.
abstract: OBJECTIVE
  To describe the characteristic magnetic resonance imaging (MRI) appearance of cerebral schistosomiasis.
  
  
  METHODS
  Twenty-five patients whose diagnosis of central nervous system (CNS) schistosomiasis had been pathologically (n = 8) and clinically (n = 17) confirmed were randomly selected. MRI was performed on a Signal 1. 5T MRI scanner before and after the intravenous administration of gadopentetate dimeglumine constrast medium. We reviewed the MRI studies obtained at the time of initial presentation, as well as follow-up studies obtained during and after medical treatment.
  
  
  RESULTS
  Immunological tests in 15 patients indicated schistosomiasis haematobium. Contrast-enhanced T1-weighted images in 22 cases showed central linear enhancement surrounded by multiple enhancing punctate nodules, which appeared "arborized". Through operation and pathological examination, 8 cases had the granuloma formation of schistosomal eggs extensive surrounded by inflammation and venous congestion. And 17 cases were treated with praziquantel and corticosteroid therapy. And they were followed up for 2 months by taking MRI, which turned out to be complete resolution of the enhancing structure and edema. At follow-up, all the patients' initial symptoms also resolved.
  
  
  CONCLUSIONS
  The specified MRI enhancement pattern of cerebral schistosomiasis is common in most cases of CNS schistosomiasis, so it should be taken account into the diagnosis of cerebral schistosomiasis.
authors.affiliation: Department of Radiology, Huashan Hospital, Fudan University, Shanghai 200040.
authors.forename: Han-Qiu
authors.initials: HQ
authors.lastname: Liu
authors.forename: Xiao-Yuan
authors.initials: XY
authors.lastname: Feng
authors.forename: Zhen-Wei
authors.initials: ZW
authors.lastname: Yao
authors.forename: Hua-Ping
authors.initials: HP
authors.lastname: Sun
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001921:Brain / Q000473:pathology*; D001927:Brain Diseases / Q000175:diagnosis* / Q000473:pathology; D002648:Child; D003287:Contrast Media; D005260:Female; D005500:Follow-Up Studies; D019786:Gadolinium DTPA; D006801:Humans; D007089:Image Enhancement; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D008875:Middle Aged; D020818:Neuroschistosomiasis / Q000175:diagnosis* / Q000473:pathology; D012553:Schistosomiasis haematobia / Q000175:diagnosis* / Q000473:pathology
chemical_list: D003287:Contrast Media; D019786:Gadolinium DTPA