Bronchioloalveolar carcinoma in congenital cystic adenomatoid malformation of lung.
Congenital cystic adenomatoid malformation (CCAM) of lung is a rare condition with the potential for malignant transformation. We report a patient who underwent lobectomy for a cystic lung lesion, which was found to be a type 1 CCAM associated with a mucinous bronchioloalveolar carcinoma. Retrospective review of a biopsy specimen from the same lobe excised during an ipsilateral empyema drainage 11 years previously showed similar foci of bronchioloalveolar carcinoma. The patient remains well 3 years after surgery. This case demonstrates the indolent nature of malignancies seen in association with type 1 CCAMs and also that complete excision, probably by lobectomy, is the treatment of choice to avoid recurrence.
West
Douglas
D
Department of Cardiothoracic Surgery, The Royal Hospital for Sick Children, Dalnair Street, Glasgow, UK. dgwest@rcsed.ac.uk
Nicholson
Andrew G
AG
Colquhoun
Ian
I
Pollock
James
J
D002282:Adenocarcinoma, Bronchiolo-Alveolar / Q000209:etiology* / Q000473:pathology / Q000601:surgery*; D000293:Adolescent; D015615:Cystic Adenomatoid Malformation of Lung, Congenital / Q000150:complications* / Q000473:pathology / Q000601:surgery*; D006801:Humans; D008175:Lung Neoplasms / Q000209:etiology* / Q000473:pathology / Q000601:surgery*; D008297:Male; D011013:Pneumonectomy