title: [Liver transplantation for the treatment of hepatocellular carcinoma].
abstract: OBJECTIVE
  To retrospectively evaluate the clinical outcomes of liver transplantation for patients with hepatocellular carcinoma (HCC).
  
  
  METHODS
  The clinical data of 88 consecutive HCC patients who underwent orthotopic liver transplantation between 2002. 4 and 2004. 7 were retrospectively reviewed. HCC stage of those patients were defined according to the pTNM classification system of UICC. All patients were followed up for more than 12 months after liver transplantation. The recurrence and overall survival rate were evaluated by univariate and multivariate analysis with SAS software.
  
  
  RESULTS
  The cumulative 1-year recurrence rate of stage I, II, III and IV after liver transplantation was 0%, 4.8%, 40.0% and 71.3%, respectively (P < 0.01). The cumulative 1-year overall survival rate of stage I, II, III and IV was 100%, 95.2%, 71.5% and 41.7%, respectively (P < 0.01).
  
  
  CONCLUSIONS
  Liver transplantation may be suitable for stage I or II hepatocellular cancer patients and improve their prognosis, while it is not suitable for stage IV HCC patients.
authors.affiliation: Department of Liver Transplantation, General Hospital of Armed Police Forces, Beijing 100039, China.
authors.forename: Xin-guo
authors.initials: XG
authors.lastname: Chen
authors.forename: Xiao-dan
authors.initials: XD
authors.lastname: Zhu
authors.forename: Wei
authors.initials: W
authors.lastname: Li
authors.forename: Yu
authors.initials: Y
authors.lastname: Liu
authors.forename: Wei-long
authors.initials: WL
authors.lastname: Zou
authors.forename: Yu-jian
authors.initials: YJ
authors.lastname: Niu
authors.forename: Feng-dong
authors.initials: FD
authors.lastname: Wu
authors.forename: Zhao-jie
authors.initials: ZJ
authors.lastname: Guan
authors.forename: Yang
authors.initials: Y
authors.lastname: Yue
mesh_terms: D000328:Adult; D000368:Aged; D006528:Carcinoma, Hepatocellular / Q000473:pathology / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008113:Liver Neoplasms / Q000473:pathology / Q000601:surgery*; D016031:Liver Transplantation; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D009367:Neoplasm Staging; D012189:Retrospective Studies; D016019:Survival Analysis; D016896:Treatment Outcome