Trends in incidences of stomach and colorectal cancer in Khon Kaen, Thailand 1985-2004.
BACKGROUND
The life styles of Thai people are changing with westernization and this would be expected to have an impact on the prevalence of cancer and other non-communicable diseases. For planning control programmes it is necessary to monitor change over time and the present study was conducted to provide information on stomach and colorectal cancer incidence rates in Khon Kaen Cancer Registry (KKCR), established in 1984 at the Faculty of Medicine, Srinagarind Hospital, Khon Kaen University.


OBJECTIVE
To assess trends in urban and rural areas of Khon Kaen province during 1985 - 2004.


METHODS
Data for stomach and colorectal cancer with an ICD-O diagnosis (coding C16 , C18 - C20) from the population-based cases of the KKCR, registered between 1985 and 2004, were retrieved and incidence trends were calculated using the Generalized Linear Model method (GLM), which generates incidence-rate-based logarithms.


RESULTS
The study population comprised 2,530 cases, 721 of stomach (males 449, females 272) and 1809 of colorectal (males 976, females 833) cancer. Most cases were aged 35-75 years. According to the histopathological diagnosis, the most common was adenocarcinoma with over 90 percent. The overall age-standardized incidence rates (ASR) for stomach cancer were 4.5 and 1.4 per 100 000 in males and females, respectively, during 1985-1989, 3.7 and 2.0 during 1990-1994, 3.0 and 2.2 during 1995-1999 and 3.6 and 1.8 during 2000-2004 . The respective figures for colorectal cancer were 3.3 and 2.6, 4.6 and 3.1, 5.4 and 3.5 and finally 5.8 and 5.3. In both urban and rural areas males were affected more frequently than females, although a shift was evident towards decrease in the se ratio was evident for colorectal cancers over time.


CONCLUSIONS
The results of this study showed slight increase in the incidence of colorectal cancer in Khon Kaen province, while rates for stomach cancer remained quite stable. The findings indicate a need for continuing research in stomach and colorectal cancer epidemiology, with subdivision into particular sites within these two sections of the gut.
Suwanrungruang
Krittika
K
Cancer Unit, Faculty of Medicine, Khon Kaen University, Khon Kaen 4002, Thailand.
Wiangnon
Surapon
S
Sriamporn
Supannee
S
Sookprasert
Aumkae
A
Rangsrikajee
Dhanes
D
Kamsa-Ard
Supot
S
Horsith
Sujinant
S
Usantia
Pakanant
P
D000328:Adult; D015179:Colorectal Neoplasms / Q000453:epidemiology*; D005260:Female; D006801:Humans; D015994:Incidence; D016014:Linear Models; D008297:Male; D008875:Middle Aged; D012042:Registries; D013274:Stomach Neoplasms / Q000453:epidemiology*; D013785:Thailand / Q000453:epidemiology