title: Rapid sequence intubation without a neuromuscular blocking agent in a 14-year-old female patient with myasthenia gravis.
abstract: The anesthesia care of a 14-year-old female patient with an acute exacerbation of myasthenia gravis (MG) and a full stomach who required emergency surgery for placement of a hemodialysis catheter is described. A nonventilated rapid sequence induction was successful with the use of propofol, lidocaine, remifentanil, cricoid pressure and no neuromuscular blocking agent. Although the use of combinations of i.v. anesthetic agents have been suggested for tracheal intubation without the need for neuromuscular blocking agents, none of these techniques has been advocated for rapid sequence intubation. We review existing literature on the topic of tracheal intubation using remifentanil and propofol without a neuromuscular blocking agent and on the topic of tracheal intubation of patients with MG using i.v. anesthesia and no neuromuscular blocking agents.
authors.affiliation: Department of Anesthesiology, University of Virginia Health System, Charlottesville, VA, USA. gdp8a@virginia.edu
authors.forename: George D
authors.initials: GD
authors.lastname: Politis
authors.forename: Joseph D
authors.initials: JD
authors.lastname: Tobias
mesh_terms: D000293:Adolescent; D000758:Anesthesia / Q000379:methods*; D002404:Catheterization; D000075202:Contraindications; D005260:Female; D006801:Humans; D007442:Intubation, Intratracheal / Q000295:instrumentation* / Q000379:methods; D008991:Monitoring, Physiologic; D009157:Myasthenia Gravis / Q000150:complications; D019148:Neuromuscular Blockade / Q000009:adverse effects; D017063:Outcome Assessment, Health Care; D013997:Time Factors