Profiling the chlorogenic acids and other caffeic acid derivatives of herbal chrysanthemum by LC-MSn.
Four samples of herbal chrysanthemum have been profiled qualitatively by LC-MS5 to identify their component chlorogenic acids and partially characterize other caffeic acid derivatives. The chlorogenic acids were minor components, and the four samples varied markedly in profile. Three p-coumaroylquinic acids, three feruloylquinic acids, four caffeoylquinic acids, six dicaffeoylquinic acids, and two tricaffeoylquinic acids were detected, 13 for the first time from this source. Partial characterization of minor components suggested the presence of five caffeoyl-hexose esters and caffeic acid-4-beta-d-glucose that have not previously been reported from this source, and eight caffeoylquinic acid glycosides and 16 dicaffeoylquinic acid glycosides that have not previously been reported in nature. Succinic acid-containing chlorogenic acids and chlorogenic acids based on epi-quinic acid, previously reported in Chrysanthemum spp., were not detected in these samples.
Clifford
Michael N
MN
School of Biomedical and Molecular Sciences, Centre for Nutrition and Food Safety, University of Surrey, Guildford, Surrey GU2 7XH, United Kingdom. m.clifford@surrey.ac.uk
Wu
Weiguo
W
Kirkpatrick
Jo
J
Kuhnert
Nikolai
N
D002109:Caffeic Acids / Q000032:analysis*; D002726:Chlorogenic Acid / Q000032:analysis*; D031202:Chrysanthemum / Q000737:chemistry*; D035264:Flowers / Q000737:chemistry; D011801:Quinic Acid / Q000031:analogs & derivatives / Q000032:analysis; D019802:Succinic Acid / Q000032:analysis
D002109:Caffeic Acids; C472707:caffeoylquinic acid; D011801:Quinic Acid; D002726:Chlorogenic Acid; D019802:Succinic Acid