title: Integrated, sequential, and contingent screening for Down syndrome - local needs should drive methodology.
authors.forename: Philip
authors.initials: P
authors.lastname: Wyatt
mesh_terms: D000328:Adult; D015415:Biomarkers / Q000097:blood; D003362:Cost-Benefit Analysis; D004314:Down Syndrome / Q000097:blood / Q000175:diagnosis* / Q000191:economics; D005260:Female; D006801:Humans; D008403:Mass Screening / Q000379:methods*; D011247:Pregnancy; D011261:Pregnancy Trimester, First; D011262:Pregnancy Trimester, Second; D011296:Prenatal Diagnosis / Q000191:economics / Q000379:methods*; D018570:Risk Assessment
chemical_list: D015415:Biomarkers