title: Time-resolved, 3-dimensional magnetic resonance flow analysis at 3 T: visualization of normal and pathological aortic vascular hemodynamics.
abstract: Flow-sensitive 3-dimensional magnetic resonance imaging at 3 T and advanced 3-dimensional visualization were used to visualize local and global vascular hemodynamics in the thoracic aorta. In patients with pathological geometric alterations of the thoracic aorta, this technique revealed considerable changes in local blood flow characteristics, compared with normal volunteers. Specifically, relatively small geometric changes, such as a partially thrombosed aortic arch or a mild aneurysm of the ascending aorta, resulted in major disturbances of local blood flow patterns within and even further downstream to the pathology.
authors.affiliation: Department of Diagnostic Radiology, University Hospital Freiburg, Freiburg, Germany.
authors.forename: Alex
authors.initials: A
authors.lastname: Frydrychowicz
authors.forename: Andreas
authors.initials: A
authors.lastname: Harloff
authors.forename: Bernd
authors.initials: B
authors.lastname: Jung
authors.forename: Maxim
authors.initials: M
authors.lastname: Zaitsev
authors.forename: Ernst
authors.initials: E
authors.lastname: Weigang
authors.forename: Thorsten A
authors.initials: TA
authors.lastname: Bley
authors.forename: Mathias
authors.initials: M
authors.lastname: Langer
authors.forename: Jürgen
authors.initials: J
authors.lastname: Hennig
authors.forename: Michael
authors.initials: M
authors.lastname: Markl
mesh_terms: D000328:Adult; D001013:Aorta, Thoracic / Q000473:pathology* / Q000502:physiology / Q000503:physiopathology*; D005260:Female; D006801:Humans; D021621:Imaging, Three-Dimensional; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D012039:Regional Blood Flow; D013997:Time Factors