title: Conservative surgical and orthodontic management of a child with central giant cell granuloma.
abstract: Differential diagnosis and treatment modalities of giant cell granulomas have been a controversial matter since Jaffe first distinguished true giant cell tumours (TGCG) from central giant cell granulomas (CGCG). CGCG is a slowly growing and painless tumour usually treated by simple curettage but denotes a strong tendency to recurrence. A case report is presented to describe conservative therapy of CGCG in the maxilla of a young child: surgical enucleation of the tumour at the age of 11 years, though successful, was followed by progressive impaction of the maxillary right permanent canine. Orthodontic treatment aligned the maxillary teeth to accommodate autotransplantation of the impacted tooth. Clinical and radiographic evaluation of the patient 5 years after the initial surgical treatment showed good bony and periodontal healing around the transplanted canine and no recurrence of the CGCG. As the literature shows that distinction of the two tumours is difficult even by histological means, various clinico-pathologic factors involved in prognostic evaluation are discussed.
authors.affiliation: Department of Orthodontics and Pedodontics, School of Dentistry, University of Geneva, Switzerland.
authors.forename: J P
authors.initials: JP
authors.lastname: Schatz
authors.forename: J P
authors.initials: JP
authors.lastname: Bernard
authors.forename: F K
authors.initials: FK
authors.lastname: Byloff
authors.forename: J
authors.initials: J
authors.lastname: Samson
mesh_terms: D002648:Child; D003481:Cuspid / Q000637:transplantation; D003970:Diastema / Q000628:therapy; D005500:Follow-Up Studies; D006101:Granuloma, Giant Cell / Q000601:surgery* / Q000628:therapy; D006801:Humans; D008297:Male; D008439:Maxillary Diseases / Q000601:surgery* / Q000628:therapy; D009971:Orthodontics, Corrective; D014087:Tooth Movement Techniques; D014095:Tooth, Impacted / Q000601:surgery; D014182:Transplantation, Autologous; D014945:Wound Healing