title: Copper-catalyzed double N-alkenylation of amides: an efficient synthesis of di- or trisubstituted N-acylpyrroles.
abstract: An efficient copper-catalyzed double alkenylation of amides with (1Z,3Z)-1,4-diiodo-1,3-dienes is reported for the first time. The reactions proceed to afford di- or trisubstituted N-acylpyrroles in good to excellent yields using CuI as the catalyst, Cs2CO3 as the base, and rac-trans-N,N'-dimethylcyclohexane-1,2-diamine as the ligand.
authors.affiliation: Department of Chemistry and Shanghai Key Laboratory of Green Chemistry and Chemical Processes, East China Normal University, 3663 North Zhongshan Road, Shanghai 200062, P. R. China.
authors.forename: Xiyuan
authors.initials: X
authors.lastname: Yuan
authors.forename: Xiaobing
authors.initials: X
authors.lastname: Xu
authors.forename: Xiaobo
authors.initials: X
authors.lastname: Zhou
authors.forename: Jiwei
authors.initials: J
authors.lastname: Yuan
authors.forename: Lugen
authors.initials: L
authors.lastname: Mai
authors.forename: Yanzhong
authors.initials: Y
authors.lastname: Li