Hysterectomy among women with HIV: indications and incidence.
OBJECTIVE
To describe hysterectomy rates and indications among women with HIV and to compare them with at-risk HIV-seronegative women.


METHODS
Reports of hysterectomy were collected from 3752 participants in a prospective cohort study of women with HIV and comparison uninfected women. Available operative notes were retrieved and abstracted. Comparisons were made using the Fisher exact, chi, Wilcoxon 2-sample, and Student's t tests.


RESULTS
Incident hysterectomy was performed for 106 (4.5%) of 2361 HIV-seropositive women, most often for cervical neoplasia, and for 24 (2.9%) of 837 HIV-seronegative women (P = 0.04). The incidence of hysterectomy was 7.7 per 1000 person-years for HIV-seropositive women and 5.3 per 1000 person-years for HIV-seronegative women (P = 0.09). HIV-seropositive and HIV-seronegative women undergoing incident hysterectomy were similar, except for a higher likelihood of an abnormal preoperative Papanicolaou test result in the former (P = 0.001). Surgical indications did not differ by serostatus.


CONCLUSIONS
Women with HIV are more likely than uninfected women to require a hysterectomy, most often for cervical neoplasia.
Massad
L Stewart
LS
Department of Obstetrics and Gynecology, Southern Illinois University School of Medicine, Springfield, IL 62794, USA. lsmassad@ameritech.net
Evans
Charlesnika
C
Weber
Kathleen
K
Cejtin
Helen E
HE
Golub
Elizabeth T
ET
DiGilio
Kathy
K
Alpern
Amy
A
Watts
D Heather
DH
D015331:Cohort Studies; D005260:Female; D005831:Genital Diseases, Female / Q000150:complications / Q000601:surgery; D015658:HIV Infections / Q000601:surgery*; D018023:HIV Seronegativity; D006679:HIV Seropositivity / Q000150:complications; D006801:Humans; D007044:Hysterectomy / Q000706:statistics & numerical data; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000601:surgery; D011446:Prospective Studies; D014481:United States