Systematic survey of nonspecific agglutination by Candida spp. in latex assays.
In order to demonstrate that cells of Candida spp. may show considerable nonspecific agglutination in latex agglutination tests, 150 clinical and reference isolates of 12 yeast species were systematically studied by applying various test parameters. In fact, 40 (26.7%) of these isolates revealed nonspecific results, significantly associated with the time allowed for agglutination.
Becker
Karsten
K
Institute of Medical Microbiology, University of Münster, D-48149 Münster, Germany. kbecker@uni-muenster.de
Almasri
Ahmed S
AS
von Eiff
Christof
C
Peters
Georg
G
Heilmann
Christine
C
Fegeler
Wolfgang
W
D002175:Candida / Q000302:isolation & purification*; D002177:Candidiasis / Q000175:diagnosis*; D005189:False Positive Reactions; D006801:Humans; D007841:Latex Fixation Tests; D012680:Sensitivity and Specificity; D013997:Time Factors