Perinatal outcome following renal transplantation.
OBJECTIVE
To assess pregnancy outcomes in a population of renal transplant recipients in Mexico.


METHODS
A total of 75 pregnancies in 60 patients managed at the National Institute of Perinatology, Mexico City, Mexico, were reviewed.


RESULTS
The mean age at conception was 26.97+/-5.42 years and the mean time from transplantation to pregnancy was 5.49+/-3.6 years. Prepregnancy renal function was determined by serum creatinine level (mean, 1.32+/-0.73 mg/dL). Prepregnancy hypertension was noted in 45.3% of the patients. Urinary tract infection was the most common complication, followed by pregnancy-induced hypertension. The pregnancy resulted in abortion in 11 patients and in live birth for the remaining 64 participants. The mean+/-SD gestational age at birth was 37.1+/-3 weeks, and intrauterine growth restriction was noted in 12 newborns. A serum creatinine level of 1.5 mg/dL or higher prior to pregnancy was associated with delivery before the 34th week and low birth weight.


CONCLUSIONS
In this study, pregnancy ended in a live birth in 84% of women with a renal transplant.
Cruz Lemini
M C
MC
Department of Obstetrics, National Institute of Perinatology, Mexico City, Mexico. cruzlemini@prodigy.net.mx <cruzlemini@prodigy.net.mx>
Ibargüengoitia Ochoa
F
F
Villanueva González
M A
MA
D000328:Adult; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D016030:Kidney Transplantation; D011247:Pregnancy; D011248:Pregnancy Complications / Q000453:epidemiology; D011256:Pregnancy Outcome; D012189:Retrospective Studies