title: BBGD: an online database for blueberry genomic data.
abstract: BACKGROUND
  Blueberry is a member of the Ericaceae family, which also includes closely related cranberry and more distantly related rhododendron, azalea, and mountain laurel. Blueberry is a major berry crop in the United States, and one that has great nutritional and economical value. Extreme low temperatures, however, reduce crop yield and cause major losses to US farmers. A better understanding of the genes and biochemical pathways that are up- or down-regulated during cold acclimation is needed to produce blueberry cultivars with enhanced cold hardiness. To that end, the blueberry genomics database (BBDG) was developed. Along with the analysis tools and web-based query interfaces, the database serves both the broader Ericaceae research community and the blueberry research community specifically by making available ESTs and gene expression data in searchable formats and in elucidating the underlying mechanisms of cold acclimation and freeze tolerance in blueberry.
  
  
  METHODS
  BBGD is the world's first database for blueberry genomics. BBGD is both a sequence and gene expression database. It stores both EST and microarray data and allows scientists to correlate expression profiles with gene function. BBGD is a public online database. Presently, the main focus of the database is the identification of genes in blueberry that are significantly induced or suppressed after low temperature exposure.
  
  
  CONCLUSIONS
  By using the database, researchers have developed EST-based markers for mapping and have identified a number of "candidate" cold tolerance genes that are highly expressed in blueberry flower buds after exposure to low temperatures.
authors.affiliation: Department of computer and information sciences, Towson University, 7800 York Road, Towson, Maryland, 21252, USA. nalkharouf@towson.edu
authors.forename: Nadim W
authors.initials: NW
authors.lastname: Alkharouf
authors.forename: Anik L
authors.initials: AL
authors.lastname: Dhanaraj
authors.forename: Dhananjay
authors.initials: D
authors.lastname: Naik
authors.forename: Chris
authors.initials: C
authors.lastname: Overall
authors.forename: Benjamin F
authors.initials: BF
authors.lastname: Matthews
authors.forename: Lisa J
authors.initials: LJ
authors.lastname: Rowland
mesh_terms: D029798:Blueberry Plants / Q000235:genetics*; D030541:Databases, Genetic; D020224:Expressed Sequence Tags; D018745:Genome, Plant; D015698:Genomic Library