title: Salivary analysis of patients with chronic renal failure undergoing hemodialysis.
abstract: This study evaluated the flow rate and composition of whole saliva in patients with chronic renal failure undergoing hemodialysis. In the group on dialysis (RG) (n = 15), saliva was collected just prior to hemodialysis CT1) and at completion (T2), while in the healthy subjects (HG)(n = 15) saliva was collected at the same time of day as the pre-dialysis. Saliva samples were analyzed by inductively coupled argon plasma with atomic emission spectrometry. Significant differences were found in the flow rate, potassium, magnesium and phosphorus concentrations at the RG-T1 and HG (p < 0.05). Sodium concentration at RG-T1 and RG-T2 were higher than HG (p < 0.05). Total protein concentration was higher at RG-T1 than at the other two analyses. Salivary peroxidase activity at RG-T1 and RG-T2 was lower than at HG. Our findings suggest that in patients with chronic renal failure, the saliva is altered. Hemodialysis, however, seems to help control saliva composition and flow rate.
authors.affiliation: Department of Pediatric Dentistry and Orthodontics, School of Dentistry, Federal University of Rio de Janeiro, Brazil. carlamartins@ig.com.br
authors.forename: Carla
authors.initials: C
authors.lastname: Martins
authors.forename: Walter Luiz
authors.initials: WL
authors.lastname: Siqueira
authors.forename: Elizabeth
authors.initials: E
authors.lastname: de Oliveira
authors.forename: Laura Salignac de Souza Guimarães
authors.initials: LS
authors.lastname: Primo
authors.forename: José
authors.initials: J
authors.lastname: Nicolau
mesh_terms: D000328:Adult; D017742:Dental Care for Chronically Ill; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000150:complications / Q000378:metabolism* / Q000628:therapy; D008274:Magnesium / Q000032:analysis; D008297:Male; D008875:Middle Aged; D009909:Oral Health; D010758:Phosphorus / Q000032:analysis; D011188:Potassium / Q000032:analysis; D012016:Reference Values; D006435:Renal Dialysis; D012463:Saliva / Q000737:chemistry / Q000378:metabolism*; D012466:Salivary Gland Diseases / Q000175:diagnosis / Q000209:etiology / Q000378:metabolism*; D012472:Salivation / Q000502:physiology*; D012636:Secretory Rate; D012964:Sodium / Q000032:analysis
chemical_list: D010758:Phosphorus; D012964:Sodium; D008274:Magnesium; D011188:Potassium