Pharmacokinetics of tramadol is affected by MDR1 polymorphism C3435T.
Slanar
Ondrej
O
Nobilis
Milan
M
Kvétina
Jaroslav
J
Matousková
Olga
O
Idle
Jeffrey R
JR
Perlík
Frantisek
F
D019540:Area Under Curve; D019389:Cytochrome P-450 CYP2D6 / Q000235:genetics*; D018432:Drug Resistance, Multiple / Q000235:genetics*; D005838:Genotype; D006207:Half-Life; D006801:Humans; D009294:Narcotics / Q000378:metabolism / Q000493:pharmacokinetics*; D011110:Polymorphism, Genetic; D014147:Tramadol / Q000378:metabolism / Q000493:pharmacokinetics*
D009294:Narcotics; D014147:Tramadol; D019389:Cytochrome P-450 CYP2D6