title: A green synthesis of isatoic anhydrides from isatins with urea-hydrogen peroxide complex and ultrasound.
abstract: The oxidation of isatins at room temperature, using the cheap and environmentally friendly urea-hydrogen peroxide complex and ultrasonic irradiation, has been investigated. The ultrasonic irradiation dramatically reduces the reaction time. With easy and reproducible reaction procedures, different isatoic anhydrides were obtained in excellent yield and with high purity.
authors.affiliation: University of Sofia, Faculty of Chemistry, 1164 Sofia, Bulgaria. Electronic address: ohttgd@chem.uni-sofia.bg.
authors.forename: Todor
authors.initials: T
authors.lastname: Deligeorgiev
authors.affiliation: University of Sofia, Faculty of Chemistry, 1164 Sofia, Bulgaria.
authors.forename: Aleksey
authors.initials: A
authors.lastname: Vasilev
authors.affiliation: University of Alcalá, Faculty of Pharmacy, 28871 Alcalá de Henares, Madrid, Spain.
authors.forename: Juan J
authors.initials: JJ
authors.lastname: Vaquero
authors.affiliation: University of Alcalá, Faculty of Pharmacy, 28871 Alcalá de Henares, Madrid, Spain.
authors.forename: Julio
authors.initials: J
authors.lastname: Alvarez-Builla