title: Antifungal property and phytochemical screening of the crude extracts of Funtumia elastica and Mallotus oppositifolius.
abstract: The antifungal properties of aqueous and ethanol extracts of Funtumia elastica and Mallotus oppositifolius were carried out using the disc diffusion agar assay. The crude extracts exhibited definite significant antifungal activity on most of the fungi. The zone of inhibition varied for the fungi, which were: Aspergillus flavus, Candida albicans, Microsporium audouinii, Penicillium sp, Trichophyton mentagrophytes, Trichoderma sp and Trichosporon cutaneum with respect to the type of plant extract. The aqueous extracts of Mallotus oppositifolius had the highest zone of inhibition of 24.75 +/- 0.86 mm on Penicillium sp. The fulcin antibiotic had zone of inhibition of 11.94 +/- 0.43 mm on Microsporium audouinii, being its highest inhibition on any of the fungi tested. Preliminary phytochemical studies of F elastica and M oppositifolius extracts revealed that they contain anthocyanins, butacyanin, flavonoids, steroids and tannins. Phytobutanin was absent in the extracts. Heavy metal analysis of plant materials showed absence of cadmium, zinc, lead, chromium and nickel, while the presence of copper iron and manganese was less than 0.95%.
authors.affiliation: Department of Botany and Microbiology, University of Lagos, Yaba, Nigeria. aaded@yahoo.com
authors.forename: A A
authors.initials: AA
authors.lastname: Adekunle
authors.forename: A M
authors.initials: AM
authors.lastname: Ikumapayi
mesh_terms: D000470:Alkaloids / Q000737:chemistry* / Q000494:pharmacology*; D000935:Antifungal Agents / Q000494:pharmacology*; D029062:Apocynaceae / Q000737:chemistry; D006801:Humans; D036461:Mallotus Plant / Q000737:chemistry; D009181:Mycoses / Q000188:drug therapy*; D009549:Nigeria; D008517:Phytotherapy; D010865:Pilot Projects; D010936:Plant Extracts / Q000737:chemistry*; D010946:Plants, Medicinal / Q000737:chemistry*
chemical_list: D000470:Alkaloids; D000935:Antifungal Agents; D010936:Plant Extracts