title: [Severe lactic acidosis associated to metformin intoxication].
abstract: Metformin is a biguanide extensively used in the treatment of type II diabetes mellitus. Between the nocive effects of the metformin emphasizes tha lactic acidosis because of its low frecuency but potential severity. The diagnosis of the poisoning due to metformin is based on the coexistence of lactic acidosis and one or more of the risk factors. The development of lactic acidosis in metformin poisoning is associated to a range of 50-80% of mortality.
authors.affiliation: Servicio de Medicina Intensiva, Hospital Universitario Marquis de Valdecilla, Santander.
authors.forename: M S
authors.initials: MS
authors.lastname: Holanda Peña
authors.forename: B
authors.initials: B
authors.lastname: Suberviola Cañas
authors.forename: A
authors.initials: A
authors.lastname: González Castro
authors.forename: J M
authors.initials: JM
authors.lastname: Marco Moreno
authors.forename: P
authors.initials: P
authors.lastname: Ugarte Peña
mesh_terms: D000140:Acidosis, Lactic / Q000139:chemically induced*; D000368:Aged; D006801:Humans; D007004:Hypoglycemic Agents / Q000506:poisoning*; D008297:Male; D008687:Metformin / Q000506:poisoning*; D012720:Severity of Illness Index
chemical_list: D007004:Hypoglycemic Agents; D008687:Metformin