title: Development and validation of Yin-Deficiency Questionnaire.
abstract: This study describes development and validation of a questionnaire as an adjunct to Traditional Chinese Medicine diagnosis of Yin-Deficiency Syndrome (Yin-DS). The Yin-Deficiency Questionnaire 1 (Yin-DQ1) consists of 10 items. Seventy-nine healthy volunteers and 44 patients diagnosed with Yin-DS were enrolled for the evaluation of discriminant validity and factorial validity. Another group of 83 healthy volunteers participated for test-retest reliability test. Internal consistency was high in both groups (Cronbach's alpha = 0.8615). Test-retest reliability (Spearman's rank correlation coefficient) ranged from 0.54 to 0.79 (p < 0.01). Factor analysis demonstrated that a two factor solution best explained the variance in responses (51.62%). The scores of all items in patients diagnosed with Yin-DS were significantly higher compared with those of healthy volunteers. The data show the internal consistency, test-retest reliability and strong discriminative properties of the Yin-DQ1. Further research determining the optimal cut-off score for Yin-DS and testing its usage as an outcome measure in a clinical trial is needed.
authors.affiliation: Institute of Korean Medicine for Healthy Living, Seoul, South Korea.
authors.forename: Sangjae
authors.initials: S
authors.lastname: Lee
authors.forename: Jongbae
authors.initials: J
authors.lastname: Park
authors.forename: Hyangsook
authors.initials: H
authors.lastname: Lee
authors.forename: Kwangho
authors.initials: K
authors.lastname: Kim
mesh_terms: D000328:Adult; D005163:Factor Analysis, Statistical; D005260:Female; D006305:Health Status Indicators; D006306:Health Surveys; D006801:Humans; D008297:Male; D008516:Medicine, Chinese Traditional; D008875:Middle Aged; D015203:Reproducibility of Results; D011795:Surveys and Questionnaires; D016710:Yin Deficiency / Q000175:diagnosis* / Q000503:physiopathology