title: [Distribution of human papillomavirus types in Shenzhen women].
abstract: OBJECTIVE
  To investigate the status of genital infection as well as distribution of types of human papillomavirus (HPV) in women in Shenzhen and provide population data for the future vaccine intervention on cervical cancer.
  
  
  METHODS
  Women with age between 15 and 59 years were selected in cluster stratified sampling from Huaqiaocheng community, Nanshan district, Shenzhen and received a population-based cervical cancer screening. After consent, every woman was interviewed by using questionnaire and tested by liquid-based cytology and HPV DNA (hybrid capture 2 and gene chips typing) separately.
  
  
  RESULTS
  Totally 1 137 women were screened. The rate of high risk HPV of hybrid capture 2 test (14. 0% ) was higher than gene chips typing test (9. 8%) (chi(2) = 27. 198, P < 0. 001) ; the consistency of the two tests was acceptable ( kappa = 0. 498, P < 0. 001). The rates of low risk HPV types and other types of gene chips typing test in this population were 1. 9% and 0. 2% respectively. The percentages of HPV 16, 18 and 58 in HPV positive women were 29. 7% , 18. 9% and 18. 9%. The rates of different age group of low risk HPV were 1. 4% (17-34), 1. 7% (35-44) and 3. 2% (45-59) , respectively.
  
  
  CONCLUSIONS
  HPV 16, 18, and 58 are the most popular types in the study population. The differences of infection rates of high risk HPV are due primarily to the variation of HPV16 distribution among age-specific population. The chances of being affected by low risk HPV will increase with age.
authors.affiliation: Department of Epidemiology, Shanxi Medical University, Taiyuan 030001, China.
authors.forename: Ju-fang
authors.initials: JF
authors.lastname: Shi
authors.forename: Rui-fang
authors.initials: RF
authors.lastname: Wu
authors.forename: Zhi-hua
authors.initials: ZH
authors.lastname: Liu
authors.forename: Qing-zhi
authors.initials: QZ
authors.lastname: Zhou
authors.forename: Ni
authors.initials: N
authors.lastname: Li
authors.forename: Na
authors.initials: N
authors.lastname: Wu-Lan
authors.forename: Qing
authors.initials: Q
authors.lastname: Li
authors.forename: Qian
authors.initials: Q
authors.lastname: Wang
authors.forename: Bin
authors.initials: B
authors.lastname: Liu
authors.forename: Rui-Zhen
authors.initials: RZ
authors.lastname: Li
authors.forename: You-lin
authors.initials: YL
authors.lastname: Qiao
mesh_terms: D000293:Adolescent; D000328:Adult; D052685:Alphapapillomavirus / Q000145:classification* / Q000302:isolation & purification; D002681:China / Q000453:epidemiology; D005260:Female; D006801:Humans; D008875:Middle Aged; D030361:Papillomavirus Infections / Q000453:epidemiology* / Q000821:virology; D014412:Tumor Virus Infections / Q000453:epidemiology* / Q000821:virology; D002577:Uterine Cervical Diseases / Q000453:epidemiology / Q000821:virology*