title: A new technique for assessing arterial pressure wave forms and central pressure with tissue Doppler.
abstract: BACKGROUND
  Non-invasive assessment of arterial pressure wave forms using applanation tonometry of the radial or carotid arteries can be technically challenging and has not found wide clinical application. 2D imaging of the common carotid arteries is routinely used and we sought to determine whether arterial waveform measurements could be derived from tissue Doppler imaging (TDI) of the carotid artery.
  
  
  METHODS
  We studied 91 subjects (52 men, age 52 +/- 14 years) with and without cardiovascular disease. Tonometry was performed on the carotid artery simultaneously with pulsed wave Doppler of the LVOT and acquired digitally. Longitudinal 2D images of the common carotid artery with and without TDI were also acquired digitally and both TDI and tonometry were calibrated using mean and diastolic cuff pressure and analysed off line.
  
  
  RESULTS
  Correlation between central pressure by TDI and tonometry was excellent for maximum pressure (r = 0.97, p < 0.0001). The mean differences between central pressures derived by TDI and tonometry were minimal (systolic 5.36 +/- 5.5 mmHg; diastolic 1.2 +/- 1.2 mmHg).
  
  
  CONCLUSIONS
  Imaging of the common carotid artery motion with tissue Doppler may permit acquisition of a waveform analogous to that from tonometry. This method may simplify estimation of central arterial pressure and calculation of total arterial compliance.
authors.affiliation: University of Queensland Department of Medicine, Princess Alexandra Hospital, Ipswich Rd, Brisbane Q4102, Australia. b.haluska@uq.edu.au
authors.forename: Brian A
authors.initials: BA
authors.lastname: Haluska
authors.forename: Leanne
authors.initials: L
authors.lastname: Jeffriess
authors.forename: Phillip M
authors.initials: PM
authors.lastname: Mottram
authors.forename: Stephane G
authors.initials: SG
authors.lastname: Carlier
authors.forename: Thomas H
authors.initials: TH
authors.lastname: Marwick
mesh_terms: D001783:Blood Flow Velocity; D001794:Blood Pressure; D001795:Blood Pressure Determination / Q000379:methods*; D017536:Carotid Artery, Common / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D015150:Echocardiography, Doppler / Q000379:methods*; D005260:Female; D006801:Humans; D006973:Hypertension / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D008297:Male; D008875:Middle Aged; D011673:Pulsatile Flow