title: Genetic Analysis of Chromomere 3d4 in DROSOPHILA MELANOGASTER: The DUNCE and SPERM-AMOTILE Genes.
abstract: Both male and female Drosophila that are homozygous deficient for chromomere 3D4 are viable but sterile and lack detectable cAMP-specific phosphodiesterase activity. Two genes have been localized to this region: spermamotile (sam) and dunce (dnc). The sperm-amotile gene is required for male fertility, and the dunce gene is required for normal learning, female fertility, and cAMP-specific phosphodiesterase activity. The sperm-amotile gene maps 0.24 map units to the left of dunce. The expression of the dunce gene seems to be affected by a chromosomal break to the left of sperm-amotile. The fertility of dunce females varies according to changes in the genetic background and the presence or absence of an X-linked suppressor.
authors.affiliation: Department of Genetics, University of California, Davis, California 95616.
authors.forename: H K
authors.initials: HK
authors.lastname: Salz
authors.forename: R L
authors.initials: RL
authors.lastname: Davis
authors.forename: J A
authors.initials: JA
authors.lastname: Kiger