Quantification of human bocavirus in lower respiratory tract infections in China.
A quantitative PCR method was established to quantify human bocavirus (HBoV) genomic copies in clinical specimens from children with lower respiratory tract infections (LRTI) in China. A total of 257 respiratory tract specimens were tested, and 7 (2.7%) of these (all sputum samples) were positive, with genomic copies that ranged from 8.0 x 10(3) to 8.0 x 10(9) in the samples. The main clinical symptom of patients who were positive for HBoV DNA was a pneumonia-like syndrome represented by high fever and cough. Our results suggest that HBoV may be an important etiological agent of LRTI in children in China.
Lin
Feng
F
Wenling First Hospital, Wenling, Zhejiang Province, China. linfengwyy@vip.sina.com
Zeng
Aiping
A
Yang
Ningmin
N
Lin
Haiyan
H
Yang
En
E
Wang
Shengqi
S
Pintel
David
D
Qiu
Jianming
J