A novel method to obtain modulus image of soft tissues using ultrasound water jet indentation: a phantom study.
The alteration of tissue stiffness is generally known to be associated with pathological changes. Ultrasound indentation is one of the methods that can be used to assess the mechanical properties of the soft tissues. It uses a flat-ended ultrasound transducer to directly contact the tissue to sense tissue deformation under an applied load. This paper introduced a novel noncontact ultrasound indentation system using water jet compression. The key idea was to utilize a water jet as the indenter as well as the coupling medium for propagation of the ultrasound beam. High frequency focused ultrasound (20 MHz) was used to measure the indentation deformation at a microscopic level. It has been demonstrated that the system could effectively assess the tissue-mimic phantoms with different stiffness. Water jet coupling allows the system to conduct C-scan on soft tissues rapidly and conveniently. By applying different pressures while taking C-scan sequences, the modulus images of the phantoms could be obtained based on the applied pressure and the phantom deformation and thickness. This paper presented the preliminary results on gel phantoms. The spatial resolution, the contrast resolution of the measurements and the reproducibility of the results were also discussed.
Lu
Min-Hua
MH
Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hong Kong, China. minhua.lu@polyu.edu.hk
Zheng
Yong-Ping
YP
Huang
Qing-Hua
QH
D003238:Connective Tissue / Q000000981:diagnostic imaging* / Q000502:physiology*; D004548:Elasticity; D006244:Hardness; D006245:Hardness Tests / Q000379:methods*; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D019047:Phantoms, Imaging; D010812:Physical Stimulation / Q000295:instrumentation / Q000379:methods*; D011312:Pressure; D013314:Stress, Mechanical; D014463:Ultrasonography / Q000295:instrumentation / Q000379:methods*; D014867:Water
D014867:Water