title: Macropodumines D and E, two new alkaloids with unusual skeletons from Daphniphyllum macropodum Miq.
abstract: [structure: see text] Two new complex polycyclic alkaloids, macropodumines D (1) and E (2), both possessing unprecedented skeletons, along with four known related alkaloids, were isolated from the leaves and barks of Daphniphyllum macropodum Miq. The structures including the relative stereochemistry of new compounds 1 and 2 were elucidated on the basis of detailed spectroscopic data analysis.
authors.affiliation: State Key Laboratory of Drug Research, Shanghai Institute of Material Medica, Chinese Academy of Science, Shanghai 201203, People's Republic of China.
authors.forename: Zhen-Yu
authors.initials: ZY
authors.lastname: Li
authors.forename: Ping
authors.initials: P
authors.lastname: Chen
authors.forename: Hong-Gui
authors.initials: HG
authors.lastname: Xu
authors.forename: Yi-Ming
authors.initials: YM
authors.lastname: Yang
authors.forename: Shu-Ying
authors.initials: SY
authors.lastname: Peng
authors.forename: Zhong-Zhen
authors.initials: ZZ
authors.lastname: Zhao
authors.forename: Yue-Wei
authors.initials: YW
authors.lastname: Guo
mesh_terms: D000470:Alkaloids / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D019684:Magnoliopsida / Q000737:chemistry*; D015394:Molecular Structure; D024301:Plant Bark / Q000737:chemistry; D018515:Plant Leaves / Q000737:chemistry; D010946:Plants, Medicinal; D011083:Polycyclic Compounds / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
chemical_list: D000470:Alkaloids; D011083:Polycyclic Compounds; C518571:macropodumine D; C518570:macropodumine E