"Recurrent" posterior reversible encephalopathy syndrome: report of 3 cases--PRES can strike twice!
In a retrospective review, 3 (3.8%) of 78 patients developed recurrent posterior reversible encephalopathy syndrome. Underlying clinical conditions included sickle cell disease, antibody-positive autoimmune disease, and allogeneic bone marrow transplantation. Infection (bacterial/viral) was suspected or documented in both episodes in all 3 patients. Evidence of endothelial injury (schistocyte formation and increased lactate dehydrogenase) was documented in all patients, and multiple organ dysfunction syndrome developed during the hospital course of all admissions.
Sweany
Jon M
JM
Department of Medicine, UPMC Shadyside Hospital, PA, USA.
Bartynski
Walter S
WS
Boardman
John F
JF
D000328:Adult; D001929:Brain Edema / Q000175:diagnosis*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D009102:Multiple Organ Failure / Q000175:diagnosis*; D012008:Recurrence; D012189:Retrospective Studies; D013577:Syndrome; D014057:Tomography, X-Ray Computed