title: Botulinum toxin: from life-threatening disease to novel medical therapy.
abstract: Botulinum toxin A is the newest therapy for the treatment of a variety of medical disorders caused by abnormalities of muscle activity. After successful use in other medical subspecialties, the newest applications of this potent neurotoxin are within the lower urinary tract. The toxin has evolved from a cause of fatal disease into the newest neuropharmacologic medical therapy.
authors.affiliation: Division of Female Pelvic Medicine and Reconstructive Surgery, University Hospitals of Cleveland, Cleveland, OH, USA.
authors.forename: Sangeeta T
authors.initials: ST
authors.lastname: Mahajan
authors.forename: Linda
authors.initials: L
authors.lastname: Brubaker
mesh_terms: D001905:Botulinum Toxins / Q000627:therapeutic use; D019274:Botulinum Toxins, Type A / Q000627:therapeutic use*; D001906:Botulism / Q000209:etiology; D006801:Humans; D009465:Neuromuscular Agents / Q000627:therapeutic use*
chemical_list: D009465:Neuromuscular Agents; D001905:Botulinum Toxins; D019274:Botulinum Toxins, Type A