Fly-casting in protein-DNA binding: frustration between protein folding and electrostatics facilitates target recognition.
Levy
Yaakov
Y
Center for Theoretical Biological Physics, University of California at San Diego, 9500 Gilman Drive, La Jolla, California 92093, USA. koby.levy@weizmann.ac.il
Onuchic
José N
JN
Wolynes
Peter G
PG
D004247:DNA / Q000737:chemistry*; D004268:DNA-Binding Proteins / Q000737:chemistry*; D006801:Humans; D011485:Protein Binding; D011487:Protein Conformation; D017510:Protein Folding; D055672:Static Electricity; D050808:ets-Domain Protein Elk-4 / Q000737:chemistry
D004268:DNA-Binding Proteins; D050808:ets-Domain Protein Elk-4; D004247:DNA