title: Early restenosis after drug-eluting stent implantation: A putative role for platelet activation.
abstract: Drug-eluting stents (DES) reduce intimal hyperplasia and restenosis, but they also inhibit stent endothelization, making the vascular surface more thrombogenic. The present report describes two cases of in-stent restenosis after DES deployment at exactly the same sites where subacute stent thrombosis had occurred. Extremely careful follow-up is mandatory after the recognition of intraluminal thrombi inside DES because restenosis may occur at the same site of DES thrombosis.
authors.affiliation: Institute of Cardiology, Ferrarotto Hospital, University of Catania, Italy.
authors.forename: Corrado
authors.initials: C
authors.lastname: Tamburino
authors.forename: Gian Paolo
authors.initials: GP
authors.lastname: Ussia
authors.forename: Marco
authors.initials: M
authors.lastname: Zimarino
authors.forename: Alfredo R
authors.initials: AR
authors.lastname: Galassi
authors.forename: Raffaele
authors.initials: R
authors.lastname: De Caterina
mesh_terms: D000368:Aged; D015906:Angioplasty, Balloon, Coronary; D019917:Blood Vessel Prosthesis Implantation / Q000009:adverse effects; D023903:Coronary Restenosis / Q000209:etiology / Q000503:physiopathology*; D016503:Drug Delivery Systems; D016903:Drug Monitoring; D004730:Endothelium, Vascular / Q000187:drug effects / Q000473:pathology*; D005260:Female; D006801:Humans; D008297:Male; D015539:Platelet Activation / Q000187:drug effects; D018570:Risk Assessment; D012307:Risk Factors; D015607:Stents / Q000009:adverse effects*; D013997:Time Factors