Using red-free monochromatic conversions of nonmydriatic digital fundus images.
OBJECTIVE
To compare three types of digital images for assessment of retinal nerve fiber layer (RNFL) defects: red-free RNFL images, color nonmydriatic images, and digitally converted nonmydriatic red-free fundus images.


METHODS
Diagnostic test comparison.


METHODS
Ninety-five image sets of three type images were evaluated. Converted images were acquired from nonmydriatic digital images by converting them into red-free, monochromatic images with graphics software. Taking RNFL images as standards, the sensitivities/specificities of nonmydriatic digital color and converted images were evaluated for detecting wedge-shaped defect (WSD) or diffuse atrophy.


RESULTS
In terms of WSD, the sensitivity/specificity of converted images were 85.7%/95.5%, and those of nonmydriatic were 83.9%/91.0%. Regarding diffuse atrophy, the sensitivity/specificity of converted images were 60.0%/97.8%, and those of nonmydriatic were 60.0%/98.9%. Intragrader/intergrader agreements for converted images were 0.849/0.793 (WSD) and 0.417/0.614 (diffuse atrophy).


CONCLUSIONS
Converted nonmydriatic fundus images without pupillary dilation are as effective as conventional red-free RNFL images for detecting WSD.
Han
Eui Seok
ES
Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Korea.
Park
Ki Ho
KH
D001284:Atrophy; D003941:Diagnostic Techniques, Ophthalmological; D005654:Fundus Oculi; D005901:Glaucoma / Q000175:diagnosis*; D006801:Humans; D009412:Nerve Fibers / Q000473:pathology*; D009898:Optic Disk / Q000473:pathology*; D009901:Optic Nerve Diseases / Q000175:diagnosis*; D010781:Photography / Q000295:instrumentation*; D015203:Reproducibility of Results; D012165:Retinal Ganglion Cells / Q000473:pathology*; D012680:Sensitivity and Specificity