Indolizidine and quinolizidine alkaloids.
This review covers the isolation, structure determination, synthesis, chemical transformations and biological activity of indolizidine and quinolizidine alkaloids. Included in the review are the hydroxylated indolizidines lentiginosine, swainsonine, castanospermine and their analogues; alkaloids from animal sources, including ants, amphibians and beetles; indolizidine alkaloids from the genera Polygonatum, Prosopis and Elaeocarpus; indolizidine and phenanthroindolizidine alkaloids; alkylquinolizidine alkaloids, including myrtine, epimyrtine, plumerinine and Lycopodium metabolites; Lythraceae and Nuphar alkaloids; lupine alkaloids; and alkaloids from marine sources. 150 references are cited.
Michael
Joseph P
JP
Molecular Sciences Institute, School of Chemistry, University of the Witwatersrand, Wits 2050, South Africa. jmichael@chem.wits.ac.za
D000470:Alkaloids / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D007212:Indolizines / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D015394:Molecular Structure; D010946:Plants, Medicinal / Q000737:chemistry*; D011807:Quinolizines / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology
D000470:Alkaloids; D007212:Indolizines; D011807:Quinolizines