Severity of Clostridium difficile-associated disease (CDAD) in allogeneic stem cell transplant recipients: evaluation of a CDAD severity grading system.
The purpose of this study was to develop and test a Clostridium difficile-associated disease (CDAD) grading system based on presenting symptoms in allogeneic stem cell transplant recipients. Patients with severe CDAD had significantly shorter median survival times and more adverse outcomes than patients with mild or moderate CDAD.
Dubberke
Erik R
ER
Division of Infectious Diseases, Washington University School of Medicine, St. Louis, MO 63110, USA. edubberk@im.wustl.edu
Sadhu
Justin
J
Gatti
Robert
R
Reske
Kimberly A
KA
DiPersio
John F
JF
Devine
Steven M
SM
Fraser
Victoria J
VJ
D016360:Clostridioides difficile; D004761:Enterocolitis, Pseudomembranous / Q000401:mortality / Q000503:physiopathology*; D006801:Humans; D012720:Severity of Illness Index; D033581:Stem Cell Transplantation; D014184:Transplantation, Homologous