Cell transplantation therapy for stroke.
No treatment currently exists to restore lost neurological function after stroke. A growing number of studies highlight the potential of stem cell transplantation as a novel therapeutic approach for stroke. In this review we summarize these studies, discuss potential mechanisms of action of the transplanted cells, and emphasize the need to determine parameters that are critical for transplantation success.
Bliss
Tonya
T
Department of Neurosurgery, Stanford University, Stanford, CA 94305, USA.
Guzman
Raphael
R
Daadi
Marcel
M
Steinberg
Gary K
GK
D000818:Animals; D016380:Brain Tissue Transplantation / Q000379:methods; D017690:Cell Transplantation / Q000379:methods; D006801:Humans; D033581:Stem Cell Transplantation / Q000379:methods*; D020521:Stroke / Q000473:pathology / Q000601:surgery*