Exploring a new, connective Pummerer reaction: formation of oxindoles by the reaction of thiols with glyoxamides.
The reaction of a range of thiols with mono- and bis-glyoxamides derived from secondary anilines, triggers a new, connective Pummerer cyclisation process and leads to the formation of oxindoles.
Miller
Marc
M
School of Chemistry, University of Manchester, Oxford Rd., Manchester, UKM13 9PL.
Tsang
William
W
Merritt
Andrew
A
Procter
David J
DJ