title: Lipomatous meningioma.
abstract: We present a case of intracranial lipomatous meningioma in the parietal convexity in a 64-year-old woman. The mass showed low density on computed tomography, was hyper-intense on T1-weighted magnetic resonance images, and had decreased intensity upon imaging with fat-suppressed sequences. Gross total removal of the tumor was performed. Histopathologically, the tumor was a meningioma with mixed transitional and lipomatous patterns. Immunohistochemically, the meningothelial foci were positive for epithelial membrane antigen (EMA) and vimentin, and negative for S-100 protein. The lipomatous foci were positive for EMA, vimentin, and S-100 protein. The Ki-67 index values of the meningothelial and lipomatous foci were 1.0% and 1.8%, respectively. We review previous reports of lipomatous meningioma and discuss its clinical presentations and pathology.
authors.affiliation: Department of Neurosurgery, Keio University School of Medicine, 35 Shinano-machi, Shinjuku-ku, Tokyo 160-8582, Japan. di045009@sc.itc.keio.ac.jp
authors.forename: Shigeo
authors.initials: S
authors.lastname: Ohba
authors.forename: Kazunari
authors.initials: K
authors.lastname: Yoshida
authors.forename: Takekazu
authors.initials: T
authors.lastname: Akiyama
authors.forename: Eiji
authors.initials: E
authors.lastname: Ikeda
authors.forename: Takeshi
authors.initials: T
authors.lastname: Kawase
mesh_terms: D014408:Biomarkers, Tumor / Q000032:analysis / Q000378:metabolism; D004847:Epithelial Cells / Q000378:metabolism / Q000473:pathology; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D019394:Ki-67 Antigen / Q000032:analysis / Q000378:metabolism; D008067:Lipoma / Q000473:pathology* / Q000503:physiopathology; D008279:Magnetic Resonance Imaging; D008577:Meningeal Neoplasms / Q000473:pathology* / Q000503:physiopathology; D008579:Meningioma / Q000473:pathology* / Q000503:physiopathology; D008875:Middle Aged; D018396:Mucin-1 / Q000032:analysis / Q000378:metabolism; D009378:Neoplasms, Multiple Primary / Q000473:pathology / Q000503:physiopathology; D019635:Neurosurgical Procedures; D010296:Parietal Lobe / Q000473:pathology / Q000503:physiopathology; D014057:Tomography, X-Ray Computed; D014746:Vimentin / Q000032:analysis / Q000378:metabolism
chemical_list: D014408:Biomarkers, Tumor; D019394:Ki-67 Antigen; D018396:Mucin-1; D014746:Vimentin