Infantile hypertrophic pyloric stenosis in infants treated with azithromycin.
Seven-week-old 32-week premature triplets were hospitalized because of rhinorrhea, cough with color change and posttussive emesis. One infant had a positive direct fluorescent antibody test for Bordetella pertussis, so all were treated with 5 days of azithromycin. Two of the infants were subsequently diagnosed with hypertrophic pyloric stenosis and underwent surgical pyloromyotomies 6 and 7 weeks, respectively, after the initial admission.
Morrison
Wynne
W
University of Pennsylvania School of Medicine, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA. morrisonw@email.chop.edu
D000900:Anti-Bacterial Agents / Q000009:adverse effects* / Q000627:therapeutic use; D017963:Azithromycin / Q000009:adverse effects* / Q000627:therapeutic use; D001886:Bordetella pertussis / Q000302:isolation & purification; D003371:Cough; D003490:Cyanosis; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007235:Infant, Premature, Diseases / Q000139:chemically induced / Q000188:drug therapy; D046248:Pyloric Stenosis, Hypertrophic / Q000139:chemically induced* / Q000175:diagnosis / Q000601:surgery; D012220:Rhinitis; D014310:Triplets; D014839:Vomiting; D014917:Whooping Cough / Q000188:drug therapy*
D000900:Anti-Bacterial Agents; D017963:Azithromycin