A DNA-damaging sesquiterpene and other constituents from Frullania nisquallensis.
Bioassay-guided fractionation of an MeCOEt extract of Frullania nisquallensis Sull. has furnished a DNA-damaging sesquiterpene, costunolide (1), and two inactive compounds, a sesquiterpene (-)-frullanolide (2) and a tridepside tenuiorin (3). (13)C-NMR data of 3 are reported.
Kim
Y C
YC
Department of Chemistry, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061-0212, USA.
da S Bolzani
V
V
Baj
N
N
Gunatilaka
A A
AA
Kingston
D G
DG