title: New approach to the synthesis of macrocyclic tetralactones via ring-closing metathesis using Grubbs' first-generation catalyst.
abstract: A facile and efficient route to synthesize macrocyclic tetralactones with different ring sizes having a wide variety of spacers is described. The application of ring-closing metathesis for the synthesis of macrocyclic tetralactones is demonstrated with many examples in excellent yield. The representative structure of macrocyclic tetralactones is characterized by X-ray crystallography.
authors.affiliation: School of Chemistry, Bharathidasan University, Tiruchirappalli, Tamilnadu 620 024, India. muthu@bdu.ac.in
authors.forename: Sengodagounder
authors.initials: S
authors.lastname: Muthusamy
authors.forename: Boopathy
authors.initials: B
authors.lastname: Gnanaprakasam
authors.forename: Eringathodi
authors.initials: E
authors.lastname: Suresh