title: Human immunodeficiency virus-infected subjects have no altered myocardial perfusion.
abstract: We assessed myocardial perfusion (blinded interpretation of a single-photon emission computed tomography) and known risk factors for atherosclerosis in 105 randomly selected human immunodeficiency virus (HIV)-infected patients in a clinic in Mexico City and in a community sample of 105 age and gender-matched infection-free subjects. An abnormal scan was obtained in 4.8% of the infected and in 7.6% of the non-infected subjects. Severity of scintigraphic abnormalities was similar in both groups. In these Mexican HIV-infected patients, despite a long time of infection and of exposure to combined antiretroviral therapy and to other classical risk factors for atherosclerosis, there was no evidence of increased risk for abnormal myocardial perfusion. Dissimilar magnitude in the hazard of coronary heart disease may occur among infected populations with different frequencies of traditional predisposing factors for cardiovascular illness.
authors.forename: Andres
authors.initials: A
authors.lastname: Catzin-Kuhlmann
authors.forename: Arturo
authors.initials: A
authors.lastname: Orea-Tejeda
authors.forename: Lilia
authors.initials: L
authors.lastname: Castillo-Martínez
authors.forename: Eloisa
authors.initials: E
authors.lastname: Colín-Ramírez
authors.forename: Daniel
authors.initials: D
authors.lastname: Asz
authors.forename: Víctor H
authors.initials: VH
authors.lastname: Aguirre
authors.forename: Luis E
authors.initials: LE
authors.lastname: Herrera
authors.forename: Victoria
authors.initials: V
authors.lastname: Valles
authors.forename: Carlos A
authors.initials: CA
authors.lastname: Aguilar-Salinas
authors.forename: Juan
authors.initials: J
authors.lastname: Sierra
authors.forename: Juan J
authors.initials: JJ
authors.lastname: Calva
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D003326:Coronary Circulation / Q000502:physiology*; D003327:Coronary Disease / Q000209:etiology; D003430:Cross-Sectional Studies; D005260:Female; D015658:HIV Infections / Q000000981:diagnostic imaging / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D015899:Tomography, Emission-Computed, Single-Photon