miRNAs in the biology of cancers and viral infections.
MicroRNAs (miRNAs) are non-coding small RNAs that play important roles in a variety of biological pathways including cellular proliferation and apoptosis. Recent studies have linked the expression of selected miRNAs to carcinogenesis and viral pathogenesis. Here, we will discuss examples of roles served by cellular miRNAs and virus-encoded miRNAs in the development of cancers and viral diseases.
Yeung
Man Lung
ML
Molecular Virology Section, Laboratory of Molecular Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892-0460, USA.
Bennasser
Yamina
Y
Jeang
Kuan-Teh
KT
D017209:Apoptosis; D049109:Cell Proliferation; D006801:Humans; D035683:MicroRNAs / Q000502:physiology*; D009369:Neoplasms / Q000209:etiology* / Q000235:genetics; D014777:Virus Diseases / Q000209:etiology* / Q000235:genetics
D035683:MicroRNAs