Biosynthesis of isonorargemonine, eschscholtzidine and 4-hydroxyeschscholtzidine in Thalictrum minus.
Feeding experiments with (14)C-labelled reticuline have shown that reticuline is an efficient precursor of isonorargemonine, eschscholtzidine, and 4-hydroxyeschscholtzidine in Thalictrum minus (Ranunculaceae). Feeding experiments using (14)C-labelled isonorargemonine and eschscholtzidine led to the conclusion that the substitution pattern of 4-hydroxyeschscholtzidine can be formed at the pavine stage.
Sidjimov
A K
AK
Faculty of Chemistry, University of Sofia, 1 James Bourchier Avenue, 1126 Sofia, Bulgaria.