An automated image-collection system for crystallization experiments using SBS standard microplates.
As part of a structural genomics platform in a university laboratory, a low-cost in-house-developed automated imaging system for SBS microplate experiments has been designed and constructed. The imaging system can scan a microplate in 2-6 min for a 96-well plate depending on the plate layout and scanning options. A web-based crystallization database system has been developed, enabling users to follow their crystallization experiments from a web browser. As the system has been designed and built by students and crystallographers using commercially available parts, this report is aimed to serve as a do-it-yourself example for laboratory robotics.
Brostromer
Erik
E
National Laboratory of Protein Engineering and Plant Genetic Engineering, Peking University, Beijing 100871, People's Republic of China.
Nan
Jie
J
Su
Xiao Dong
XD
D001331:Automation; D003460:Crystallization / Q000295:instrumentation* / Q000379:methods; D003625:Data Collection; D016208:Databases, Factual; D003952:Diagnostic Imaging / Q000295:instrumentation*; D023281:Genomics / Q000295:instrumentation; D046228:Microarray Analysis / Q000295:instrumentation* / Q000379:methods; D012371:Robotics / Q000295:instrumentation* / Q000379:methods