Intracranial arteriovenous malformation with maternal carbamazepine use.
1 1/2 month old child born to primigravida mother on prolonged carbamazepine therapy presented with recurrent seizures. The child had abnormal facies and was diagnosed to be having arteriovenous malformation with intracranial hemorrhage on neuroimaging. This case suggests that development of arteriovenous malformation in a child with maternal carbamazepine therapy may occur as a part of clinical profile of 'fetal anticonvulsant syndrome'.
Narang
Manish
M
Department of Pediatrics, University College of Medical Sciences and GTB Hospital, Delhi, India. manish_2710@yahoo.com
Shah
Dheeraj
D
Natasha
Gupta
G
D000328:Adult; D002220:Carbamazepine / Q000009:adverse effects* / Q000627:therapeutic use; D002533:Cerebral Angiography; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007223:Infant; D002538:Intracranial Arteriovenous Malformations / Q000139:chemically induced* / Q000000981:diagnostic imaging / Q000601:surgery; D008279:Magnetic Resonance Imaging; D018811:Maternal Exposure / Q000009:adverse effects; D019635:Neurosurgical Procedures / Q000379:methods; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects / Q000139:chemically induced* / Q000000981:diagnostic imaging / Q000601:surgery; D012307:Risk Factors
D002220:Carbamazepine