Allergic contact dermatitis to methyl aminolevulinate (Metvix) cream used in photodynamic therapy.
Topical photodynamic therapy (PDT) is increasingly used in the treatment of superficial skin malignancies including actinic keratosis, Bowen's disease and superficial basal cell carcinoma. Contact allergy to the prodrug is rarely reported. We report a case of allergic contact dermatitis to methyl aminolevulinate cream used in PDT.
Harries
Matthew J
MJ
The Dermatology Centre, The University of Manchester, Hope Hospital, Stott Lane, Salford, Manchester, UK. mjharries@doctors.org.uk
Street
Gill
G
Gilmour
Elizabeth
E
Rhodes
Lesley E
LE
Beck
Michael H
MH
D000368:Aged; D000622:Aminolevulinic Acid / Q000009:adverse effects / Q000031:analogs & derivatives*; D017449:Dermatitis, Allergic Contact / Q000209:etiology*; D004485:Eczema / Q000188:drug therapy; D005260:Female; D006801:Humans; D007866:Leg; D010778:Photochemotherapy / Q000009:adverse effects*; D017319:Photosensitizing Agents / Q000009:adverse effects*
D017319:Photosensitizing Agents; C475457:methyl 5-aminolevulinate; D000622:Aminolevulinic Acid