Chronic diarrhea--an unusual presentation of metastatic invasive lobular cancer of breast.
We report a 56-year-old lady with chronic diarrhea and weight loss. She had undergone lumpectomy with axillary clearance (node positive) four years ago for invasive lobular carcinoma of breast. Investigations revealed involvement of almost the entire gut with skip areas. Biopsies from the stomach showed presence of signet-ring cells, suggestive of metastases from invasive lobular carcinoma of breast. Estrogen receptor immuno-staining was positive, confirming the diagnosis. She was treated initially with octreotide and later with chemotherapeutic agents, with transient relief in diarrhea. She succumbed eight months later.
Jhaveri
Ajay
A
Department of Gastroenterology, Jaslok Hospital and Research Center, Bhatia Hospital, Mumbai, India.
Nagral
Aabha
A
Dhaber
Boman
B
Sampat
Mrudula
M
Shah
Samir
S
D001943:Breast Neoplasms / Q000473:pathology*; D018275:Carcinoma, Lobular / Q000556:secondary*; D018279:Carcinoma, Signet Ring Cell / Q000150:complications / Q000473:pathology / Q000556:secondary*; D002908:Chronic Disease; D003967:Diarrhea / Q000209:etiology*; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D008875:Middle Aged; D013274:Stomach Neoplasms / Q000150:complications / Q000473:pathology / Q000556:secondary*; D015431:Weight Loss