High-density lipoprotein cholesterol: an emerging target for stroke treatment.
OBJECTIVE
This review characterizes the current state of knowledge of high-density lipoprotein (HDL) in relation to stroke.


RESULTS
HDL has anti-atherosclerotic and anti-inflammatory properties and is an important component in atherosclerosis. Serum HDL-cholesterol levels are inversely related to heart disease and stroke risk. There are various established and experimental treatments which can raise serum HDL cholesterol and improve its function.


CONCLUSIONS
HDL is an emerging target for atherosclerotic stroke treatment with the potential to dramatically impact the care of stroke patients.
Sanossian
Nerses
N
Department of Neurology, University of Southern California, Los Angeles, CA 90033, USA. sanossia@yahoo.com
Saver
Jeffrey L
JL
Navab
Mohamad
M
Ovbiagele
Bruce
B
D008076:Cholesterol, HDL / Q000097:blood*; D016503:Drug Delivery Systems / Q000379:methods*; D006801:Humans; D000960:Hypolipidemic Agents / Q000008:administration & dosage*; D020521:Stroke / Q000097:blood* / Q000188:drug therapy
D008076:Cholesterol, HDL; D000960:Hypolipidemic Agents