title: Heavy tools for genome mining.
abstract: In this issue of Chemistry & Biology, Gross et al. report development of a novel genome mining method for isolating products of orphan biosynthetic gene clusters, and the application of this method to the isolation of orfamide A, a novel cyclic lipopeptide.
authors.affiliation: Department of Chemistry, University of Warwick, Coventry CV4 7AL, United Kingdom.
authors.forename: Christophe
authors.initials: C
authors.lastname: Corre
authors.forename: Gregory L
authors.initials: GL
authors.lastname: Challis
mesh_terms: D001688:Biological Products / Q000302:isolation & purification; D019295:Computational Biology / Q000379:methods*; D023281:Genomics / Q000379:methods*; D008074:Lipoproteins / Q000302:isolation & purification; D010456:Peptides, Cyclic / Q000302:isolation & purification
chemical_list: D001688:Biological Products; D008074:Lipoproteins; D010456:Peptides, Cyclic