title: Selective intercalation of six ligand molecules in a self-assembled triple helix.
abstract: The addition of a ligand molecule to an artificial self-assembled triple helix leads to the selective intercalation of two hydrogen-bonded trimers in specific binding pockets. Furthermore, the triple helix suffers large conformational rearrangements in order to accommodate the ligand molecules in a highly organized manner.
authors.affiliation: Laboratory of Supramolecular Chemistry and Technology, MESA+ Institute for Nanotechnology, Faculty of Sciences and Technology, University of Twente, P. O. Box 217, 7500AE Enschede, The Netherlands.
authors.forename: Miguel A
authors.initials: MA
authors.lastname: Mateos-Timoneda
authors.forename: Jessica M C A
authors.initials: JM
authors.lastname: Kerckhoffs
authors.forename: David N
authors.initials: DN
authors.lastname: Reinhoudt
authors.forename: Mercedes
authors.initials: M
authors.lastname: Crego-Calama
mesh_terms: D001665:Binding Sites; D002468:Cell Physiological Phenomena; D004247:DNA / Q000737:chemistry*; D006860:Hydrogen Bonding; D007364:Intercalating Agents / Q000737:chemistry*; D008024:Ligands; D009682:Magnetic Resonance Spectroscopy; D018716:Molecular Mimicry; D009690:Nucleic Acid Conformation; D011506:Proteins / Q000737:chemistry
chemical_list: D007364:Intercalating Agents; D008024:Ligands; D011506:Proteins; D004247:DNA