Changes in sin nombre virus antibody prevalence in deer mice across seasons: the interaction between habitat, sex, and infection in deer mice.
We examined the impact of season and habitat on Sin Nombre virus (SNV) seroprevalence in deer mice (Peromyscus maniculatus) in Utah's Great Basin Desert from May 2002 through summer 2003. Low mouse captures in 2002 limited analysis for that year. In two seasons during 2003, mouse density and sagebrush cover were positively linked (spring: r = 0.8, P = 0.01; summer: r = 0.8, P = 0.04). In the spring, seroprevalence was negatively correlated with density (r = -0.9, P< 0.01); male and female antibody prevalence did not differ; and scarring was unrelated to antibody status. In the summer, density and antibody prevalence were unrelated; male seroprevalence was higher (chi(2) = 3.6, P = 0.05); and seropositive mice had more scars (t = 2.5, P = 0.02). We speculate nesting behavior could maintain SNV over the winter, whereas summer territoriality could be responsible for transmission.
Pearce-Duvet
Jessica M C
JM
Biology Department, University of Utah, 257 South 1400 East, Salt Lake City, UT 84112, USA. pearce@biology.utah.edu
St Jeor
Stephen C
SC
Boone
John D
JD
Dearing
M Denise
MD
D000818:Animals; D000914:Antibodies, Viral / Q000097:blood*; D017753:Ecosystem; D005260:Female; D018804:Hantavirus Pulmonary Syndrome / Q000453:epidemiology / Q000635:transmission / Q000662:veterinary*; D008297:Male; D010542:Peromyscus / Q000821:virology; D011156:Population Density; D012376:Rodent Diseases / Q000453:epidemiology* / Q000635:transmission; D012621:Seasons; D016036:Seroepidemiologic Studies; D012737:Sex Factors; D029261:Sin Nombre virus / Q000276:immunology*; D014589:Utah / Q000453:epidemiology
D000914:Antibodies, Viral