title: Strained azetidinium ylides: new reagents for cyclopropanation.
abstract: Azetidinium ylides showed a remarkable ability to perform the cyclopropanation of Michael acceptors. Ephedrine-derived azetidinium ylides allowed the formation of substituted cyclopropanes in good yields and at a high level of stereoselectivity. The determination of the relative stereochemistries in the produced cyclopropanes gave some insight into the reaction mechanism.
authors.affiliation: Institut Lavoisier, Université de Versailles Saint-Quentin-en-Yvelines, 45 avenue des Etats-Unis, 78035 Versailles Cedex, France.
authors.forename: François
authors.initials: F
authors.lastname: Couty
authors.forename: Olivier
authors.initials: O
authors.lastname: David
authors.forename: Bénédicte
authors.initials: B
authors.lastname: Larmanjat
authors.forename: Jérôme
authors.initials: J
authors.lastname: Marrot
mesh_terms: D000475:Alkenes / Q000737:chemistry*; D001384:Azetidines / Q000737:chemistry*; D003521:Cyclopropanes / Q000737:chemistry*; D004809:Ephedrine / Q000737:chemistry; D007202:Indicators and Reagents; D008956:Models, Chemical; D013237:Stereoisomerism
chemical_list: D000475:Alkenes; D001384:Azetidines; D003521:Cyclopropanes; D007202:Indicators and Reagents; D004809:Ephedrine