title: Blood pressure response to exercise test and serum lipids in normotensive men with positive family history of hypertension.
abstract: The aim of the study was to follow the arterial blood pressure response to exercise test and serum lipids in middle-aged normotensive men with family history (FH) of arterial hypertension. 152 normotensive men, divided into two groups: I group--92 men without FH for arterial hypertension and II group--60 men with family history for arterial hypertension were investigated. The response of blood pressure to exercise test on bicycle ergometer with progressively increasing workload up to 100 W was followed up. Five minute recovery period was followed, too. The total cholesterol (TC), high-density and low-density lipoprotein cholesterol (HDL-C and LDL-C) and triglycerides were assessed and TC/HDL-C ratio was calculated. Significant difference in the arterial blood pressure at a level of 100 W between the Ist and IInd group was found: 177 +/- 19.0/ 89 +/- 12.0 mmHg versus 189 +/- 17**/ 96 +/- 11* mmHg (* p < 0.01, ** p < 0.001). Subjects with positive FH for arterial hypertension showed higher elevation of arterial blood pressure during and after exercise: OR = 2.3 (95% CI 1.1 -4.8). The systolic blood pressure during the recovery period and TC/HDL-C ratio were significantly higher with the Ilnd group. In conclusion, our data show significantly higher reaction of blood pressure to exercise, retarded recovery of blood pressure and significantly higher TC/HDL-C ratio with the individuals with positive FH for arterial hypertension.
authors.affiliation: National Center of Public Health Protection, Sofia, Bulgaria.
authors.forename: Christo
authors.initials: C
authors.lastname: Deyanov
authors.forename: Katia
authors.initials: K
authors.lastname: Vangelova
mesh_terms: D000328:Adult; D001794:Blood Pressure / Q000502:physiology*; D005080:Exercise Test; D030342:Genetic Diseases, Inborn; D006801:Humans; D006973:Hypertension / Q000235:genetics*; D008055:Lipids / Q000097:blood*; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D018570:Risk Assessment; D012307:Risk Factors
chemical_list: D008055:Lipids