title: Polychlorinated biphenyls (PCBs) and polybrominated diphenyl ethers (PBDEs) in milk from Italian women living in Rome and Venice.
abstract: The levels of selected polychlorinated biphenyls (PCBs) and polybrominated diphenyl ethers (PBDEs) were measured in human milk samples from the areas of Venice and Rome, primarily in order to characterize the current levels of infant exposure to PCBs and PBDEs due to breast feeding in Italy. Sixteen non-dioxin-like PCBs, including the traditional indicator congeners, and 11 PBDEs, comprising the relevant PBDE-47, PBDE-99, and PBDE-153, were determined. Congeners were selected for analysis according to their relative abundance in human tissues, toxicological relevance, and diffusion in the environment. Dietary habits of the milk donors were recorded by questionnaires; mothers of the Venice area were classified into three groups according to their consumption of local fish, molluscs, and other fishery products. Sigma(16)(PCBs) and Sigma(11)(PBDEs) (ng g(-1) fat) for the areas of Venice and Rome were respectively, 250-390 and 240, and 1.6-2.8 and 4.1. An increase of fish and fishery product consumption could not be associated with an increase of PCB and PBDE levels in milk.
authors.affiliation: Toxicological Chemistry Unit, Department of the Environment and Primary Prevention, Istituto Superiore di Sanitá, 00161 Rome, Italy. ingelido@iss.it
authors.forename: Anna Maria
authors.initials: AM
authors.lastname: Ingelido
authors.forename: Terri
authors.initials: T
authors.lastname: Ballard
authors.forename: Elena
authors.initials: E
authors.lastname: Dellatte
authors.forename: Alessandro
authors.initials: A
authors.lastname: di Domenico
authors.forename: Fabiola
authors.initials: F
authors.lastname: Ferri
authors.forename: Anna Rita
authors.initials: AR
authors.lastname: Fulgenzi
authors.forename: Thomas
authors.initials: T
authors.lastname: Herrmann
authors.forename: Nicola
authors.initials: N
authors.lastname: Iacovella
authors.forename: Roberto
authors.initials: R
authors.lastname: Miniero
authors.forename: Olaf
authors.initials: O
authors.lastname: Päpke
authors.forename: Maria Grazia
authors.initials: MG
authors.lastname: Porpora
authors.forename: Elena
authors.initials: E
authors.lastname: De Felip
mesh_terms: D000328:Adult; D002947:Cities; D004032:Diet; D004785:Environmental Pollutants / Q000032:analysis / Q000378:metabolism / Q000633:toxicity; D005260:Female; D005506:Food Contamination; D055768:Halogenated Diphenyl Ethers; D006801:Humans; D007558:Italy; D008895:Milk, Human / Q000737:chemistry*; D010647:Phenyl Ethers / Q000032:analysis* / Q000378:metabolism / Q000633:toxicity; D011075:Polybrominated Biphenyls / Q000032:analysis* / Q000378:metabolism / Q000633:toxicity; D011078:Polychlorinated Biphenyls / Q000032:analysis* / Q000378:metabolism / Q000633:toxicity; D018570:Risk Assessment; D017747:Seafood / Q000633:toxicity*; D011795:Surveys and Questionnaires
chemical_list: D004785:Environmental Pollutants; D055768:Halogenated Diphenyl Ethers; D010647:Phenyl Ethers; D011075:Polybrominated Biphenyls; C086401:pentabromodiphenyl ether; D011078:Polychlorinated Biphenyls