Passive or active smoking, which is more relevant to breast cancer.
OBJECTIVE
To examine the risk of breast cancer associated with passive and active smoking and to explore risk heterogeneity among studies.


METHODS
We conducted this study in Iran during the year 2006. Fifteen published studies on smoking and breast cancer met the defined criteria. Pooled odds ratio (OR) estimates for female breast cancer were calculated. The active and passive smokers were compared with women categorized as never regularly exposed to tobacco smoke.


RESULTS
The pooled risk estimate for breast cancer associated with passive smoking among non-smokers was 1.38 (95% confidence interval [CI]; 1.16-1.65). The pooled OR for active smokers was 1.25 (95% CI; 1.11-1.41). Also, the combined OR for passive and active smokers related to breast cancer was 1.30 (95% CI; 1.17-1.45).


CONCLUSIONS
Based on the results of the pooled analysis, it can be concluded both passive and active smoking equally increase the risk of female breast cancer.
Sadri
Gholamhossein
G
Department of Biostatistics and Epidemiology, Hamadan University of Medical Sciences, PO Box. 4171, Hamadan, IR Iran. ghsadri@yahoo.co.uk
Mahjub
Hossein
H
D000328:Adult; D017677:Age Distribution; D000368:Aged; D001943:Breast Neoplasms / Q000453:epidemiology* / Q000209:etiology* / Q000503:physiopathology; D016001:Confidence Intervals; D005260:Female; D006801:Humans; D015994:Incidence; D007492:Iran / Q000453:epidemiology; D008875:Middle Aged; D016017:Odds Ratio; D011379:Prognosis; D012016:Reference Values; D012189:Retrospective Studies; D012307:Risk Factors; D017678:Sex Distribution; D012907:Smoking / Q000009:adverse effects*; D016019:Survival Analysis; D014028:Tobacco Smoke Pollution / Q000009:adverse effects*
D014028:Tobacco Smoke Pollution