Cutaneous finding in anti thymocyte globulin induced serum sickness.
Polyclonal anti-thymocyte globulin (ATG) is used as an immunosuppressive agent in the treatment of aplastic anemia (AA). Serum sickness is a recognized side effect of ATG. We observed abnormal skin manifestation in patient with aplastic anemia who had been treated with ATG. We conclude that abnormal immune function caused by aplastic anemia and ATG and corticosteroids may aggravate the signs of serum sickness.
Nabavizadeh
Seyed Hesamedin
SH
Karimi
Mehran
M
Amin
Reza
R
D000293:Adolescent; D000741:Anemia, Aplastic / Q000188:drug therapy; D000961:Antilymphocyte Serum / Q000009:adverse effects* / Q000494:pharmacology; D006801:Humans; D008297:Male; D012713:Serum Sickness / Q000139:chemically induced / Q000276:immunology / Q000473:pathology*; D012871:Skin Diseases / Q000139:chemically induced / Q000276:immunology / Q000473:pathology*
D000961:Antilymphocyte Serum