Acetaminophen-induced hepatic failure with encephalopathy in a newborn.
We report a case of oral acetaminophen toxicity in a term newborn infant successfully treated with a 20 h intravenous N-acetylcysteine infusion protocol without any adverse effects. This case report supports the use of N-acetylcysteine to treat neonatal acetaminophen toxicity and highlights the need for better education of parents regarding the appropriate use and dosage of acetaminophen in newborns.
Walls
L
L
Department of Pediatrics, University of Michigan Health System, C.S. Mott Children's Hospital, Ann Arbor, MI 48109-0254, USA.
Baker
C F
CF
Sarkar
S
S
D000082:Acetaminophen / Q000009:adverse effects* / Q000097:blood; D018712:Analgesics, Non-Narcotic / Q000009:adverse effects*; D006801:Humans; D007231:Infant, Newborn; D017114:Liver Failure, Acute / Q000139:chemically induced*; D008297:Male
D018712:Analgesics, Non-Narcotic; D000082:Acetaminophen