title: Prolonged lateral steep position impairs respiratory mechanics during continuous lateral rotation therapy in respiratory failure.
abstract: OBJECTIVE
  To establish whether prolonged lateral steep position during continuous rotation therapy leads to improvement on pulmonary gas exchange, respiratory mechanics and hemodynamics.
  
  
  METHODS
  Prospective observational study.
  
  
  METHODS
  Intensive care unit of a university hospital.
  
  
  METHODS
  Twelve consecutive patients suffering from acute lung injury or adult respiratory distress syndrome undergoing continuous rotation therapy.
  
  
  METHODS
  Blood gas analysis, static lung compliance, blood pressure, cardiac index and pulmonary shunt fraction were measured in supine as well as in left and right lateral steep position at 62 degrees during continuous rotation therapy (phase I). Rotation was then stopped for 30 min with the patients in supine position, left and right lateral steep position, and the same measurements were performed every 10 min (phase II).
  
  
  RESULTS
  Phase I and II revealed no significant changes in PaO(2)/FiO(2) ratio, mean arterial blood pressure, pulmonary shunt fraction, or cardiac index. Significantly lower static compliance was observed in lateral steep position than in supine position (p<0.001). Concomitantly, PaCO(2) was significantly lower in supine position than in left and right lateral steep position (p<0.01).
  
  
  CONCLUSIONS
  Lateral steep positioning impairs the compliance of the respiratory system. Prolonged lateral steep position does not lead to benefits with respect to oxygenation or hemodynamics. Individual response to the different positions is unpredictable. The pauses in "extreme" positions should be as short as possible.
authors.affiliation: Department of Medicine I, Medical University of Vienna, Vienna General Hospital, Waehringer Guertel 18-20, 1090, Vienna, Austria.
authors.forename: Peter
authors.initials: P
authors.lastname: Schellongowski
authors.forename: Heidrun
authors.initials: H
authors.lastname: Losert
authors.forename: Gottfried J
authors.initials: GJ
authors.lastname: Locker
authors.forename: Klaus
authors.initials: K
authors.lastname: Laczika
authors.forename: Michael
authors.initials: M
authors.lastname: Frass
authors.forename: Ulrike
authors.initials: U
authors.lastname: Holzinger
authors.forename: Andja
authors.initials: A
authors.lastname: Bojic
authors.forename: Thomas
authors.initials: T
authors.lastname: Staudinger
mesh_terms: D018806:APACHE; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001794:Blood Pressure; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011175:Positive-Pressure Respiration; D011187:Posture; D011659:Pulmonary Gas Exchange; D012128:Respiratory Distress Syndrome / Q000145:classification / Q000628:therapy*; D013990:Tidal Volume