Molecular recognition of oxoanions based on guanidinium receptors.
Guanidinium is a versatile functional group with unique properties. In biological systems, hydrogen-bonding and electrostatic interactions involving the arginine side chains of proteins are critical to stabilise complexes between proteins and nucleic acids, carbohydrates or other proteins. Leading examples of artificial receptors for carboxylates, phosphates and other oxoanions, such as sulfate or nitrate are highlighted in this tutorial review, addressed to readers interested in biology, chemistry and supramolecular chemistry.
Blondeau
Pascal
P
Institute of Chemical Research of Catalonia (ICIQ), 43007 Tarragona, Spain.
Segura
Margarita
M
Pérez-Fernández
Ruth
R
de Mendoza
Javier
J
D000838:Anions; D001665:Binding Sites; D002264:Carboxylic Acids / Q000737:chemistry*; D004247:DNA / Q000737:chemistry / Q000378:metabolism; D019791:Guanidine / Q000737:chemistry*; D008958:Models, Molecular; D011506:Proteins / Q000737:chemistry / Q000378:metabolism; D011956:Receptors, Cell Surface / Q000737:chemistry*
D000838:Anions; D002264:Carboxylic Acids; D011506:Proteins; D011956:Receptors, Cell Surface; D004247:DNA; D019791:Guanidine