Chronic arsenic poisoning: a global health issue -- a report of multiple primary cancers.
Chronic arsenic (As) poisoning is a worldwide public health problem. Effects of prolonged exposure to high levels of As in drinking water have been observed and documented in various epidemiological studies from all over the world. The non-malignant cutaneous effects of chronic exposure to inorganic As are well known. A case presenting with multiple cutaneous cancers as well as an internal lung primary in a patient exposed to toxic levels of As in the drinking water is discussed along with a review of literature.
Walvekar
R R
RR
Department of Head and Neck Surgery, Tata Memorial Hospital, Parel, Mumbai, India.
Kane
S V
SV
Nadkarni
M S
MS
Bagwan
I N
IN
Chaukar
D A
DA
D'Cruz
A K
AK
D000230:Adenocarcinoma / Q000139:chemically induced* / Q000473:pathology; D001151:Arsenic / Q000032:analysis / Q000378:metabolism; D020261:Arsenic Poisoning / Q000150:complications* / Q000473:pathology; D002294:Carcinoma, Squamous Cell / Q000139:chemically induced* / Q000473:pathology; D002908:Chronic Disease; D014943:Global Health; D006801:Humans; D008175:Lung Neoplasms / Q000139:chemically induced* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000139:chemically induced* / Q000473:pathology; D012878:Skin Neoplasms / Q000139:chemically induced* / Q000473:pathology; D016896:Treatment Outcome; D014874:Water Pollutants, Chemical / Q000009:adverse effects*; D014881:Water Supply
D014874:Water Pollutants, Chemical; D001151:Arsenic