Tannins with antimutagenic properties in the herb of Alchemilla species and Potentilla anserina.
Self-prepared ethanolic and aqueous extracts and commercial tinctures derived from the herb of Alchemilla spec. and Potentilla anserina were compared for their antimutagenic potency using 2-nitrofluorene as standard mutagen. All samples studied showed weak or moderate activities. The total amount of tannins did not correlate well with the degree of inhibition. However, tannin-free extracts did not display any inhibition of mutagenicity. Therefore, the tannin fraction participates at least partly in the antimutagenicity of the extracts examined.
Schimmer
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Institut für Botanik und Pharmazeutische Biologie der Universität Erlangen-Nürnberg, Staudtstrasse 5, D-91058 Erlangen, Germany.
Lindenbaum
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