Spliced MLL fusions: a novel mechanism to generate functional chimeric MLL-MLLT1 transcripts in t(11;19)(q23;p13.3) leukemia.
Meyer
C
C
Burmeister
T
T
Strehl
S
S
Schneider
B
B
Hubert
D
D
Zach
O
O
Haas
O
O
Klingebiel
T
T
Dingermann
T
T
Marschalek
R
R
D000208:Acute Disease; D000328:Adult; D000818:Animals; D002648:Child; D019457:Chromosome Breakage; D002880:Chromosomes, Human, Pair 11 / Q000235:genetics* / Q000648:ultrastructure; D002888:Chromosomes, Human, Pair 19 / Q000235:genetics* / Q000648:ultrastructure; D004273:DNA, Neoplasm / Q000235:genetics; D005091:Exons / Q000235:genetics; D011495:Histone-Lysine N-Methyltransferase; D006801:Humans; D007438:Introns / Q000235:genetics; D007938:Leukemia / Q000235:genetics*; D051379:Mice; D051788:Myeloid-Lymphoid Leukemia Protein / Q000737:chemistry / Q000235:genetics*; D009363:Neoplasm Proteins / Q000235:genetics*; D009687:Nuclear Proteins / Q000235:genetics*; D012333:RNA, Messenger / Q000096:biosynthesis / Q000235:genetics*; D012334:RNA, Neoplasm / Q000096:biosynthesis / Q000235:genetics*; D020040:Trans-Splicing / Q000235:genetics*; D014157:Transcription Factors / Q000235:genetics*; D014158:Transcription, Genetic; D014178:Translocation, Genetic / Q000235:genetics*
D004273:DNA, Neoplasm; C497422:KMT2A protein, human; C081448:MLLT1 protein, human; D009363:Neoplasm Proteins; D009687:Nuclear Proteins; D012333:RNA, Messenger; D012334:RNA, Neoplasm; D014157:Transcription Factors; D051788:Myeloid-Lymphoid Leukemia Protein; D011495:Histone-Lysine N-Methyltransferase