Congenital sensory neuropathy as a differential diagnosis for phagocytic immunodeficiency.
There are few reports about congenital indifference to pain or Hereditary and Sensory Autonomic Neuropathy (HSAN). Several investigations for pathophysiology of this syndrome have been performed and different classifications about it. In this report we present a case of HSAN type II with general absence of pain and self amputations and leprosy-like damage of extremities which was suspected to be phagocytic immunodeficiency due to past history of repeated ulcer and abscess formation.
Gharagozlou
Mohammad
M
Department of Immunology and Allergy, Children Hospital Medical Center, Tehran University of Medical Sciences, Tehran, Iran. gharagoz@tums.ac.ir
Zandieh
Fariborz
F
Tabatabaei
Parviz
P
Zamani
Gholamreza
G
D002675:Child, Preschool; D003937:Diagnosis, Differential; D009477:Hereditary Sensory and Autonomic Neuropathies / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D008297:Male; D010585:Phagocyte Bactericidal Dysfunction / Q000175:diagnosis* / Q000473:pathology