title: State of the art of cardiac surgery in patients with congenital heart disease.
abstract: During the last 20 years, pediatric cardiac surgery has been characterized by important changes, with reductions in surgical mortality and the achievement of complete repair at an earlier age, thus avoiding multiple procedures and strongly ameliorating the global outcome of these patients. In this review, we describe the actual trends in the surgical treatment of cardiac malformations. We analyze two groups of patients: in the first group (septal defects, tetralogy of Fallot, transposition of the great arteries, aortic stenosis and coarctation) the indications are well established and the goal is represented by a lessening of the surgical trauma and post-operative morbidity, with stable results in the follow-up. In the second group (univentricular heart, pulmonary atresia and intact ventricular septum, double discordance, conduit, hypoplastic left heart syndrome), the lesions are still considered complex and submitted to ongoing experimental and clinical research, in order to improve the post-surgical history of these diseases.
authors.affiliation: Division of Pediatric Cardiac Surgery, IRCCS Giannina Gaslini, Genoa, Italy. luciozannini@ospedale-gaslini.ge.it
authors.forename: Lucio
authors.initials: L
authors.lastname: Zannini
authors.forename: Italo
authors.initials: I
authors.lastname: Borini
mesh_terms: D001024:Aortic Valve Stenosis / Q000151:congenital / Q000601:surgery; D006348:Cardiac Surgical Procedures / Q000379:methods* / Q000639:trends; D006330:Heart Defects, Congenital / Q000601:surgery*; D006343:Heart Septal Defects / Q000601:surgery; D006801:Humans; D018636:Hypoplastic Left Heart Syndrome / Q000601:surgery; D007223:Infant; D007231:Infant, Newborn; D010372:Pediatrics / Q000379:methods* / Q000639:trends; D018633:Pulmonary Atresia / Q000601:surgery; D013771:Tetralogy of Fallot / Q000601:surgery; D014188:Transposition of Great Vessels / Q000601:surgery