title: RNAi from plants to nematodes.
abstract: Coincident with the award of the Nobel Prize for Medicine in 2006 to Fire and Mello for their discovery of RNAi, plant scientists have succeeded in using RNAi-based techniques to control nematodes, a hitherto unmanageable plant parasite. Recent work has demonstrated that the expression in a host plant of double-stranded RNA targeting housekeeping or parasitism genes in the root-knot nematode resulted in resistance to nematode infection.
authors.affiliation: Department of Molecular Biotechnology, Ghent University, Coupure links 653, 9000 Ghent, Belgium. Godelieve.Gheysen@UGent.be
authors.forename: Godelieve
authors.initials: G
authors.lastname: Gheysen
authors.forename: Bartel
authors.initials: B
authors.lastname: Vanholme
mesh_terms: D000818:Animals; D017238:Genes, Helminth; D005818:Genetic Engineering; D009348:Nematoda / Q000235:genetics* / Q000472:pathogenicity; D010935:Plant Diseases / Q000235:genetics / Q000469:parasitology*; D010944:Plants / Q000235:genetics*; D034622:RNA Interference; D012330:RNA, Double-Stranded / Q000235:genetics / Q000378:metabolism; D034741:RNA, Small Interfering / Q000235:genetics / Q000378:metabolism
chemical_list: D012330:RNA, Double-Stranded; D034741:RNA, Small Interfering