title: Skin signs of systemic disease in childhood.
abstract: Several systemic disorders of childhood are characterized by cutaneous stigmata, and these skin signs can serve as important diagnostic clues. Many of the systemic illnesses that are seen in both the pediatric and adult populations often manifest in different ways with respect to their cutaneous features. Also, there are conditions that uniquely present in childhood, such as KD, HSP, acute hemmorhagic edema of infancy, and NOMID. Early recognition of these disorders is important for initiation of appropriate therapy and prevention of adverse outcomes.
authors.affiliation: Department of Dermatology, University of California-San Francisco, 1701 Divisadero St., 3rd Floor, San Francisco, CA 94143-0316, USA. Gilliam@derm.ucsf.edu
authors.forename: Amy E
authors.initials: AE
authors.lastname: Gilliam
mesh_terms: D002648:Child; D015267:Churg-Strauss Syndrome / Q000175:diagnosis; D003882:Dermatomyositis / Q000175:diagnosis; D006801:Humans; D008178:Lupus Erythematosus, Cutaneous / Q000175:diagnosis; D008180:Lupus Erythematosus, Systemic / Q000175:diagnosis; D012594:Scleroderma, Localized / Q000175:diagnosis; D012871:Skin Diseases / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D017445:Skin Diseases, Vascular / Q000175:diagnosis