title: Breast cancer proteomics: clinical perspectives.
abstract: Breast cancer is the one of leading causes of cancer-related deaths in women within economically developed regions of the world. A major focus of present research into this malignancy is the identification of new biomarkers and drug targets to improve detection and treatment. Proteomics represents one of the latest technological developments in this context. It aims to analyse the complex circuitry of the breast cancer proteome. Here, the authors review how breast cancer proteomics has progressed so far, with emphasis on its potential application to clinically relevant scenarios.
authors.affiliation: UCD Conway Institute, UCD School of Biomolecular and Biomedical Science, University College Dublin, Belfield, Dublin 4, Ireland.
authors.forename: Thomas Y K
authors.initials: TY
authors.lastname: Lau
authors.forename: Darran P
authors.initials: DP
authors.lastname: O'Connor
authors.forename: Donal J
authors.initials: DJ
authors.lastname: Brennan
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Duffy
authors.forename: Stephen R
authors.initials: SR
authors.lastname: Pennington
authors.forename: William M
authors.initials: WM
authors.lastname: Gallagher
mesh_terms: D000818:Animals; D001943:Breast Neoplasms / Q000737:chemistry* / Q000235:genetics* / Q000628:therapy; D005260:Female; D006801:Humans; D020543:Proteome / Q000235:genetics; D040901:Proteomics / Q000379:methods* / Q000639:trends
chemical_list: D020543:Proteome