Cutaneous metastasis resembling acute dermatitis in patient with advanced gastric cancer.
The most common metastatic sites from gastric cancer are the liver, intra-abdominal lymph nodes, ovary and peritoneal cavity. Cutaneous metastasis of gastric cancer is rare, and most cutaneous metastases are typically solitary, nodular, have a firm consistency, and are red or hyperpigmented. Thus, cutaneous metastasis is easily distinguished from other skin disease. We report a case of a 60-year-old woman with cutaneous metastasis of gastric cancer, whose facial skin showed painless pruritic eczema, resembling acute dermatitis. She had earlier undergone a total gastrectomy for advanced gastric cancer in our hospital. After 14 months, she developed eczematous facial lesions; the presumptive diagnosis was acute dermatitis. However, skin biopsy unexpectedly revealed cutaneous metastasis of gastric cancer. After 6 months of systemic chemotherapy with capecitabine and cisplatin, the cutaneous metastasis was markedly improved and a clinically complete remission was accomplished.
Koo
D H
DH
Department of Internal Medicine (Division of Oncology), Asan Medical Centre, University of Ulsan College of Medicine, Seoul, Korea.
Chang
H M
HM
Jung
J Y
JY
Song
J H
JH
Lee
J L
JL
Ryu
M H
MH
Kim
T W
TW
Yook
J H
JH
Song
J S
JS
Lee
J S
JS
Kang
Y K
YK
D000970:Antineoplastic Agents / Q000627:therapeutic use; D000069287:Capecitabine; D002945:Cisplatin / Q000627:therapeutic use; D003841:Deoxycytidine / Q000031:analogs & derivatives / Q000627:therapeutic use; D003872:Dermatitis / Q000473:pathology*; D003937:Diagnosis, Differential; D005260:Female; D005472:Fluorouracil / Q000031:analogs & derivatives / Q000627:therapeutic use; D006801:Humans; D008875:Middle Aged; D012878:Skin Neoplasms / Q000175:diagnosis / Q000188:drug therapy / Q000556:secondary*; D013274:Stomach Neoplasms / Q000473:pathology*; D016896:Treatment Outcome
D000970:Antineoplastic Agents; D003841:Deoxycytidine; D000069287:Capecitabine; D002945:Cisplatin; D005472:Fluorouracil