title: Calcium pyrophosphate dihydrate deposition in the transverse ligament of the atlas: an unusual cause of cervical myelopathy.
abstract: A 75-year-old male presented with progressive myelopathy due to massive retro-odontoid deposits of calcium pyrophosphate dehydrate (CPPD) crystals. Magnetic resonance imaging revealed a non-enhanced isointense extradural mass on a T1-weighted image and a heterogeneous intense mass on a T2-weighted image. Computed tomography (CT) showed linear calcification within the mass. The mass was resected via a posterolateral approach resulting in marked improvement of the symptoms. Histological examination revealed birefringent rhomboid crystals consistent with CPPD. The preoperative differential diagnosis of periodontoid CPPD deposition disease in the elderly population should be considered, particularly if CT studies demonstrate small areas of calcification within the retro-odontoid mass.
authors.affiliation: Department of Orthopedic Surgery, Kobe University Graduate School of Medicine, Kobe, Japan. doita@med.kobe-u.ac.jp
authors.forename: M
authors.initials: M
authors.lastname: Doita
authors.forename: T
authors.initials: T
authors.lastname: Shimomura
authors.forename: K
authors.initials: K
authors.lastname: Maeno
authors.forename: K
authors.initials: K
authors.lastname: Nishida
authors.forename: H
authors.initials: H
authors.lastname: Fujioka
authors.forename: M
authors.initials: M
authors.lastname: Kurosaka
mesh_terms: D000368:Aged; D001270:Cervical Atlas / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D002574:Cervical Vertebrae / Q000000981:diagnostic imaging / Q000473:pathology*; D002805:Chondrocalcinosis / Q000150:complications* / Q000175:diagnosis / Q000601:surgery; D003937:Diagnosis, Differential; D006801:Humans; D006987:Hypesthesia / Q000209:etiology; D008022:Ligaments / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D018908:Muscle Weakness / Q000209:etiology; D010292:Paresthesia / Q000209:etiology; D035583:Rare Diseases; D013117:Spinal Cord Compression / Q000175:diagnosis / Q000209:etiology*; D014057:Tomography, X-Ray Computed / Q000379:methods; D016896:Treatment Outcome