[A new indole alkaloid glycoside from stems of Nauclea officinalis].
OBJECTIVE
To investigate the chemical constituents of water-soluble part of stem of Nauclea officinalis.


METHODS
The compounds were isolated and purified by resins, silica gel, and Sephadex LH20 column chromatography repeatedly, and their structures were identified by spectral analysis.


RESULTS
Seven compounds were isolated and identified as: naucleamide A-10-O-beta-D-glucopyranoside (I), 5-beta-carboxystrictosidin (II), sweroside (III), loganin (IV), 3,4-dimethoxyphenyl-beta-D-glucopyranoside (V), 3, 4, 5-trimethoxyphenyl-beta-D-glucopyranoside (VI), 2-phenethylrutinoside (VII).


CONCLUSIONS
Compound I is a new indole alkaloid glucoside, compounds I-VII were isolated from this plant for the first time.
Xuan
Wei-dong
WD
School of Pharmacy, Second Military Medical University, Shanghai 200433, China.
Chen
Hai-sheng
HS
Bian
Jun
J
D002243:Carbolines / Q000737:chemistry* / Q000302:isolation & purification; D005960:Glucosides / Q000737:chemistry* / Q000302:isolation & purification; D006027:Glycosides / Q000737:chemistry* / Q000302:isolation & purification; D026121:Indole Alkaloids / Q000737:chemistry* / Q000302:isolation & purification; D057888:Iridoid Glucosides; D039823:Iridoids / Q000737:chemistry / Q000302:isolation & purification; D008968:Molecular Conformation; D015394:Molecular Structure; D018547:Plant Stems / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry; D019666:Rubiaceae / Q000737:chemistry*
D002243:Carbolines; D005960:Glucosides; D006027:Glycosides; D026121:Indole Alkaloids; D057888:Iridoid Glucosides; D039823:Iridoids; C528626:naucleamide A-10-O-glucopyranoside; C059516:loganin; C049412:sweroside