title: Fixed drug eruption due to ibuprofen.
abstract: Fixed drug eruptions due to ibuprofen have rarely been reported. Two days after treatment with ibuprofen, a 61-year-old woman developed erythema and pain affecting the tongue and oral mucosa. Two months later, the patient started ibuprofen and erythromycin for a catarrhal episode with reappearance of the same lesions in the oral mucosa 24 hours later. Furthermore, two new erythematosus-violaceous maculae developed. Topical challenge through an occluded patch test with ibuprofen 5% on the residual cutaneous lesion was successful. We present an unusual case of fixed drug eruption due to ibuprofen
authors.affiliation: MIR 3, Unidad de Alergia, Hospital Gregorio Marañón, Madrid, Spain.
authors.forename: C Villanueva
authors.initials: CV
authors.lastname: Alvarez Santullano
authors.forename: V
authors.initials: V
authors.lastname: Tover Flores
authors.forename: M
authors.initials: M
authors.lastname: De Barrio Fernández
authors.forename: P
authors.initials: P
authors.lastname: Tornero Molina
authors.forename: A
authors.initials: A
authors.lastname: Prieto Garcia
mesh_terms: D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects*; D003875:Drug Eruptions / Q000175:diagnosis / Q000209:etiology*; D005260:Female; D006801:Humans; D007052:Ibuprofen / Q000009:adverse effects*; D008875:Middle Aged; D009061:Mouth Mucosa / Q000187:drug effects; D010328:Patch Tests; D013280:Stomatitis / Q000139:chemically induced*
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D007052:Ibuprofen