title: Restricted field of view magnetic resonance imaging of a dynamic time series.
abstract: A restricted field of view (rFOV) approach for imaging a dynamic time series of volumes of limited spatial extent within a larger subject is described. The shorter readout with rFOV-MRI can be exploited to either limit image artifacts or increase spatial resolution. To accomplish rFOV imaging of a multislice volume for a dynamic series, an outer volume suppression (OVS) preparation that saturates signal external to a cylinder through the subject is followed by slice-selective excitation and a spiral readout. The pass- and stopband efficiencies of the OVS in an agar gel phantom were 97% (+/-1.5%) and 3% (+/-1%), respectively. Profiles of the temporal signal-to-noise ratio (SNR) were measured in a phantom and an adult brain. The rFOV sequence reduced distortions from off-resonance signal and T2*-induced blurring compared to a conventional sequence. Sequence utility is demonstrated for high-resolution rFOV functional MRI (fMRI) in the visual cortex. The rFOV sequence may prove to be useful for other multislice dynamic and high-resolution imaging applications.
authors.affiliation: Lucas Center, Department of Radiology, Stanford University, Stanford, California 94305-5488, USA. lpisani@stanford.edu
authors.forename: Laura
authors.initials: L
authors.lastname: Pisani
authors.forename: Roland
authors.initials: R
authors.lastname: Bammer
authors.forename: Gary
authors.initials: G
authors.lastname: Glover
mesh_terms: D001931:Brain Mapping / Q000379:methods*; D005333:Fetus / Q000033:anatomy & histology*; D005782:Gels; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008279:Magnetic Resonance Imaging / Q000379:methods*; D019047:Phantoms, Imaging; D014793:Visual Cortex / Q000033:anatomy & histology*
chemical_list: D005782:Gels