A case of HHV-8-associated HIV-negative primary effusion lymphoma in Moscow.
Primary effusion lymphoma is a rare tumor of B-cell derivation which is associated with human herpes virus type 8 (HHV-8) in 100% and with human immunodeficiency virus (HIV) in most of cases. The paper describes the first case in Russia of HIV(-) HHV-8(+) Epstein-Barr virus (EBV)(+) primary effusion lymphoma in a male patient aged 56 years. The tumor was located in the pleural cavity. Interestingly, the patient was HIV-negative while having a positive tumor HHV-8 test. There are only 22 similar cases described worldwide.
Shirokov
D
D
Laboratory of Haematopoiesis Immunology, N.N.Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, Russian Federation, Moscow, Russia.
Kadyrova
E
E
Anokhina
M
M
Kondratyeva
T
T
Gourtsevich
V
V
Tupitsyn
N
N
D000914:Antibodies, Viral / Q000097:blood; D004279:DNA, Viral / Q000032:analysis / Q000235:genetics; D006678:HIV / Q000302:isolation & purification; D006566:Herpesviridae Infections / Q000821:virology*; D004854:Herpesvirus 4, Human / Q000302:isolation & purification; D019288:Herpesvirus 8, Human / Q000302:isolation & purification*; D006801:Humans; D008223:Lymphoma / Q000821:virology*; D008297:Male; D008875:Middle Aged; D009031:Moscow; D035422:Pleural Cavity / Q000473:pathology
D000914:Antibodies, Viral; D004279:DNA, Viral