Localisation of increased prefrontal white matter in pathological liars.
We examined white matter volumes in four prefrontal subregions using structural magnetic resonance imaging in 10 pathological liars, 14 antisocial controls, and 20 normal controls. Liars showed a relatively widespread increase in white matter (23-36%) in orbitofrontal, middle and inferior, but not superior, frontal gyri compared with antisocial and normal controls. This white matter increase may predispose some individuals to pathological lying.
Yang
Yaling
Y
Department of Psychology, University of Southern California, Los Angeles, and David Geffen School of Medicine, CA 90089-1061, USA. yalingy@usc.edu
Raine
Adrian
A
Narr
Katherine L
KL
Lencz
Todd
T
LaCasse
Lori
L
Colletti
Patrick
P
Toga
Arthur W
AW
D000704:Analysis of Variance; D001927:Brain Diseases / Q000473:pathology*; D016022:Case-Control Studies; D008192:Deception; D005260:Female; D006801:Humans; D008014:Lie Detection / Q000523:psychology*; D008279:Magnetic Resonance Imaging; D008297:Male; D017397:Prefrontal Cortex / Q000473:pathology*