Impact of inflammation on ocular immune privilege.
The immune-privileged status of the anterior chamber of the eye is altered in experimentally induced intraocular inflammation and in the pigment dispersion syndrome of DBA/2J mice. However, the eye has developed multiple mechanisms to maintain ocular immune privilege even in the presence of intraocular inflammation.
Mo
Jun-Song
JS
Departments of Ophthalmology and Visual Sciences, University of Louisville School of Medicine, Louisville, Ky., USA.
Wang
Wei
W
Kaplan
Henry J
HJ
D000818:Animals; D000867:Anterior Chamber / Q000276:immunology; D001327:Autoimmune Diseases / Q000276:immunology; D005123:Eye / Q000276:immunology* / Q000294:innervation; D006801:Humans; D007108:Immune Tolerance; D051379:Mice; D010047:Ovalbumin / Q000276:immunology; D016212:Transforming Growth Factor beta / Q000502:physiology; D014605:Uveitis / Q000276:immunology*
D016212:Transforming Growth Factor beta; D010047:Ovalbumin