Magnetically induced vagal nerve stimulation and food intake and body mass in growing rats.
Electrostimulation of vagal nerve (VNS) by microchip (MC) with magnetic field energy supply may "mimic" the physiological output associated with gastric mechanoreceptors activation by food and lead to decrease in food intake and subsequently decrease in weight gain. Vago-vagal reflexes in growing animals seems to be mainly responsible for meal size regulation and other compensatory (hormonal or neural) mechanisms prevent from decrease in body mass.
Ziomber
Agata
A
Katedra Patofizjologii, Collegium Medicum Uniwersytetu Jagiellońskiego, Kraków. zagataz@02.pl
Zaraska
Wiesław
W
Bugajski
Andrzej
A
Thor
Piotr J
PJ
D000818:Animals; D001835:Body Weight / Q000187:drug effects* / Q000502:physiology; D004435:Eating / Q000502:physiology*; D004558:Electric Stimulation / Q000379:methods*; D005247:Feeding Behavior / Q000502:physiology*; D020007:Implants, Experimental; D008280:Magnetics; D051381:Rats; D017208:Rats, Wistar; D016896:Treatment Outcome; D014630:Vagus Nerve / Q000502:physiology*; D015430:Weight Gain