Hyperammonemia in generalized Mycobacterium genavense infection after renal transplantation.
After solid organ transplantation, patients are susceptible to infection caused by uncommon pathogens due the immunosuppressive drug therapy. Here, we report the first case of disseminated Mycobacterium genavense infection in a HIV seronegative renal transplant patient. The most striking clinical feature was a decreased consciousness. Blood results revealed hyperammonemia with otherwise normal liver function. Occurrence of hyperammonemia and massive M. genavense infection has not been reported before.
Nurmohamed
S
S
Renal Transplant Unit, Department of Internal Medicine, Academic Medical Center University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam.
Weenink
A
A
Moeniralam
H
H
Visser
C
C
Bemelman
F
F
D000368:Aged; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D022124:Hyperammonemia / Q000175:diagnosis* / Q000382:microbiology; D016030:Kidney Transplantation; D009161:Mycobacterium / Q000302:isolation & purification*; D009164:Mycobacterium Infections / Q000150:complications / Q000175:diagnosis*; D011183:Postoperative Complications / Q000175:diagnosis* / Q000382:microbiology; D013183:Sputum / Q000382:microbiology; D014556:Urine / Q000382:microbiology