title: Retrospective analysis of esophageal food impaction: differences in etiology by age and gender.
abstract: Eosinophilic Esophagitis (EE) is an emerging cause of esophageal food impaction (EFI) not accounted for in previous studies. We sought to determine the causes of EFI in a recent cohort with recognition of EE. A retrospective chart review of all patients with EFI during the past 5 years was performed. Etiology was determined by endoscopy report, pathology results, and follow-up studies. A total of 85 EFIs occurred, in 79 patients (55 men, 30 women, age 18-100). The most common etiologies of EFI were Schatzki's ring (n = 18), peptic stricture (n = 18), EE (n = 9), esophagitis (n = 9), and no underlying diagnosis (n = 20). EE was significantly more frequent in men (P < .025) and those <50 years old (P < .025). There was a significant difference in the age at which men (median age = 44) and women (median age = 71) present with EFI (P < .001). The etiology of EFI differs significantly by age and gender. This information may be useful in evaluation and management of EFI.
authors.affiliation: University of Utah Health Sciences Center, Division of Gastroenterology, 30 North 1900 East, SOM 4R 118, Salt Lake City, UT 84132, USA. Kathryn.Byrne@hsc.utah.edu
authors.forename: Kathryn R
authors.initials: KR
authors.lastname: Byrne
authors.forename: Panagiotis H
authors.initials: PH
authors.lastname: Panagiotakis
authors.forename: Kristen
authors.initials: K
authors.lastname: Hilden
authors.forename: Kristen L
authors.initials: KL
authors.lastname: Thomas
authors.forename: Kathryn A
authors.initials: KA
authors.lastname: Peterson
authors.forename: John C
authors.initials: JC
authors.lastname: Fang
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D003680:Deglutition Disorders / Q000209:etiology*; D004802:Eosinophilia / Q000150:complications; D004941:Esophagitis / Q000150:complications; D005260:Female; D005502:Food; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012737:Sex Factors