Thiophilic interaction chromatography of human transferrins.
Lactoferrin and serum transferrin, the iron-binding proteins, are widely distributed in biological fluids. Transferrins have many biological functions: anti-bacterial, anti-inflammatory, and immunoregulatory. A facile monitoring of the concentration of transferrins in biological fluids may have medical relevance. Thiophilic-interaction chromatography of transferrins may provide an efficient means for their quantitation in serum.
Srikrishnan
Thamarapu
T
Department of Cancer Biology, Roswell Park Cancer Institute, Buffalo, New York 14263, USA. thamarapu.srikrishnan@roswellpark.org
Mackenzie
James T
JT
Sulkowski
Eugene
E
D002846:Chromatography, Affinity / Q000379:methods; D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D006801:Humans; D007781:Lactoferrin / Q000097:blood / Q000302:isolation & purification*; D014168:Transferrin / Q000032:analysis / Q000302:isolation & purification*
D014168:Transferrin; D007781:Lactoferrin