title: Isolated pulmonary cryptococcosis in an immunocompetent patient.
abstract: In this study, we report a case of pulmonary cryptococcosis in a patient presenting respiratory symptoms and a lung mass on the chest X-ray. The patient had no concomitant diseases, was seronegative for human immunodeficiency virus and was not receiving immunosuppressive therapy of any kind. The diagnosis was confirmed through transbronchial biopsy and bronchoalveolar lavage. The patient was treated as an outpatient with fluconazole (300 mg/day for six months), evolving to clinical improvement and partial regression of the lung mass, as seen on a second chest X-ray. The current case illustrates an unusual presentation of pulmonary cryptococcosis and raises questions regarding the therapeutic approaches proposed in the literature.
authors.affiliation: Universidade Estadual de Montes Claros, Montes Claros, MG, Brasil. anateresaf@terra.com.br
authors.forename: Ana Teresa Fernandes
authors.initials: AT
authors.lastname: Barbosa
authors.forename: Fernando Antônio
authors.initials: FA
authors.lastname: Colares
authors.forename: Edson da Silva
authors.initials: Eda S
authors.lastname: Gusmão
authors.forename: Amanda Araújo
authors.initials: AA
authors.lastname: Barros
authors.forename: Cristiane Gonçalves
authors.initials: CG
authors.lastname: Cordeiro
authors.forename: Maria Cecília Tolentino
authors.initials: MC
authors.lastname: Andrade
mesh_terms: D000368:Aged; D000935:Antifungal Agents / Q000627:therapeutic use; D003453:Cryptococcosis / Q000175:diagnosis* / Q000188:drug therapy; D003455:Cryptococcus neoformans / Q000302:isolation & purification*; D005260:Female; D015725:Fluconazole / Q000627:therapeutic use; D006801:Humans; D007121:Immunocompetence; D008172:Lung Diseases, Fungal / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D014057:Tomography, X-Ray Computed
chemical_list: D000935:Antifungal Agents; D015725:Fluconazole