Axially chiral NHC-Pd(II) complexes in the oxidative kinetic resolution of secondary alcohols using molecular oxygen as a terminal oxidant.
[reaction: see text] Axially chiral N-heterocyclic carbene (NHC) Pd(II) complexes were prepared from optically active 1,1'-binaphthalenyl-2,2'-diamine (BINAM) and H8-BINAM and applied in the oxidative kinetic resolution of secondary alcohols using molecular oxygen as a terminal oxidant. The corresponding sec-alcohols can be obtained in good yields with moderate to good enantioselectivities.
Chen
Tao
T
School of Chemistry & Molecular Engineering, East China University of Science and Technology, 130 Mei Long Road, Shanghai 200237 China.
Jiang
Jia-Jun
JJ
Xu
Qin
Q
Shi
Min
M