title: Acute tumor lysis syndrome caused by transcatheter oily chemoembolization in a patient with a large hepatocellular carcinoma.
abstract: Acute tumor lysis syndrome results from a sudden and rapid release of products of cellular breakdown after anticancer therapy. Severe alterations of metabolic profile might occur and result in acute renal failure. We present a patient with a large hepatocellular carcinoma who received transcatheter oily chemoembolization and died subsequently of this syndrome. To our knowledge, there has been only one report of this syndrome induced by chemoembolization for hepatocellular carcinoma. This case illustrates the need to anticipate the development of acute tumor lysis syndrome when chemoembolization is planned for a large hepatocellular carcinoma.
authors.affiliation: Department of Radiology, Hyogo Medical Center for Adults, 13-70 Kitaoji, Akashi City, Hyogo, 673-8558, Japan. saknm76@yahoo.co.jp
authors.forename: Noriaki
authors.initials: N
authors.lastname: Sakamoto
authors.forename: Shuichi
authors.initials: S
authors.lastname: Monzawa
authors.forename: Hidenobu
authors.initials: H
authors.lastname: Nagano
authors.forename: Hogara
authors.initials: H
authors.lastname: Nishizaki
authors.forename: Yasuaki
authors.initials: Y
authors.lastname: Arai
authors.forename: Kazuro
authors.initials: K
authors.lastname: Sugimura
mesh_terms: D000792:Angiography; D006528:Carcinoma, Hepatocellular / Q000098:blood supply / Q000000981:diagnostic imaging / Q000628:therapy*; D016461:Chemoembolization, Therapeutic / Q000009:adverse effects*; D003287:Contrast Media; D004305:Dose-Response Relationship, Drug; D015251:Epirubicin / Q000009:adverse effects*; D017809:Fatal Outcome; D005781:Gelatin Sponge, Absorbable; D006801:Humans; D007459:Iodized Oil; D008113:Liver Neoplasms / Q000098:blood supply / Q000000981:diagnostic imaging / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D019233:Retreatment; D036542:Tomography, Spiral Computed; D015275:Tumor Lysis Syndrome / Q000000981:diagnostic imaging / Q000209:etiology*
chemical_list: D003287:Contrast Media; D015251:Epirubicin; D007459:Iodized Oil