Classification and prevalence of pigmented lesions in patients with total-body photographs at high risk of developing melanoma.
BACKGROUND
The classification of many pigmented lesions is not well defined, and an association with melanoma has not been established.


OBJECTIVE
To better define the spectrum of pigmented lesions (excluding common and dysplastic nevi) and explore links to melanoma.


METHODS
Retrospective review of patients with total-body digital photographs at high risk of developing melanoma from the Memorial Sloan-Kettering Cancer Center Dermatology Service.


RESULTS
Among 598 patients, 7.7% had café au lait spots, 2.8% had nevi spilus, 2.3% had congenital nevus-like nevi, 2% had "other" lesions, 1.2% had segmental speckled lentiginous nevi, and 1% had agminated nevi. There was no statistical difference in the prevalence rates of these pigmented lesions in patients with or without a history of melanoma or >or= 100 nevi.


CONCLUSIONS
A wide range of pigmented lesions require further classification and study to explore possible links to melanoma.
Menon
Kavita
K
Dermatology Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY 10022, USA.
Dusza
Stephen W
SW
Marghoob
Ashfaq A
AA
Halpern
Allan C
AC
Nehal
Kishwer S
KS
D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008297:Male; D008545:Melanoma / Q000473:pathology*; D008875:Middle Aged; D009508:Nevus, Pigmented / Q000473:pathology*; D010781:Photography; D012189:Retrospective Studies; D018570:Risk Assessment; D012878:Skin Neoplasms / Q000473:pathology*