title: [Liver metastasis of colon cancer with a high serum alpha-fetoprotein level: report of a case].
abstract: We report herein a case of 72-year-old woman in whom liver metastasis of colon cancer was presented with a marked elevation of serum alpha-fetoprotein (AFP) level. She was transferred to our hospital for multiple liver masses found on ultrasonogram. Abdominal computed tomogram revealed multiple low-density masses in the liver and wall thickening of the hepatic flexure of colon. The serum AFP level was 10,718.8 ng/mL. Colonoscopic findings of ulcerofungating mass suggested liver metastasis from colon cancer. However, the possibility of combined hepatocellular carcinoma could not be ruled out due to serum AFP elevation. Both colon and liver biopsies revealed moderately differentiated tubular adenocarcinoma. Using an immunohistochemical staining, the adenocarcinoma in liver showed focal positive to AFP, but not in colon. This case represents a very rare case of colon cancer with a marked elevation of serum AFP.
authors.affiliation: Center for Liver Cancer, National Cancer Center, Goyang Korea.
authors.forename: Min
authors.initials: M
authors.lastname: An
authors.forename: Jeong A
authors.initials: JA
authors.lastname: Shin
authors.forename: Sang-Min
authors.initials: SM
authors.lastname: Lee
authors.forename: Tak
authors.initials: T
authors.lastname: Yoon
authors.forename: Weon Seo
authors.initials: WS
authors.lastname: Park
authors.forename: Joon Il
authors.initials: JI
authors.lastname: Choi
authors.forename: Chang-Min
authors.initials: CM
authors.lastname: Kim
mesh_terms: D000368:Aged; D003110:Colonic Neoplasms / Q000473:pathology*; D005260:Female; D006801:Humans; D008113:Liver Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000556:secondary*; D014057:Tomography, X-Ray Computed; D000509:alpha-Fetoproteins / Q000032:analysis*
chemical_list: D000509:alpha-Fetoproteins