Adipokines and adipocyte targets in the future management of obesity and the metabolic syndrome.
The role of adipocytes has been recently better understood. Several adipocytokines have been identified, including leptin, a main regulator of appetite and energy expenditure, adiponectin and others, as novel insulin-sensitizers/insulin-mimetics, and some others inducing insulin resistance. Adipocytokines thus represent interesting novel drug targets in the future management of obesity.
Kralisch
S
S
Department of Internal Medicine, University of Leipzig, Leipzig, Germany.
Bluher
M
M
Paschke
R
R
Stumvoll
M
M
Fasshauer
M
M
D017667:Adipocytes / Q000378:metabolism*; D001067:Appetite Depressants / Q000494:pharmacology; D006801:Humans; D007333:Insulin Resistance; D024821:Metabolic Syndrome / Q000188:drug therapy*; D009765:Obesity / Q000188:drug therapy*; D036361:Peptide Hormones / Q000378:metabolism* / Q000494:pharmacology
D001067:Appetite Depressants; D036361:Peptide Hormones