Ru-catalyzed intermolecular [3+2+1] cycloaddition of alpha,beta-unsaturated ketones with silylacetylenes and carbon monoxide leading to alpha-pyrones.
Ruthenium catalyzes a carbonylative [3+2+1] cycloaddition, using silylacetylenes, alpha,beta-unsaturated ketones, and CO as the starting materials, providing the new method for the synthesis of tetrasubstituted alpha-pyrones. In this reaction, the carbonyl group and alpha-carbon of vinyl ketones are incorporated as a three-atom assembling unit. [reaction: see text].
Fukuyama
Takahide
T
Department of Chemistry, Graduate School of Science, Osaka Prefecture University, Sakai, Osaka 599-8531, Japan.
Higashibeppu
Yuki
Y
Yamaura
Ryo
R
Ryu
Ilhyong
I
D000480:Alkynes / Q000138:chemical synthesis*; D002248:Carbon Monoxide / Q000737:chemistry*; D002384:Catalysis; D003500:Cyclization; D007202:Indicators and Reagents; D007659:Ketones / Q000138:chemical synthesis*; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D011753:Pyrones / Q000138:chemical synthesis*; D012428:Ruthenium / Q000737:chemistry*; D012821:Silanes / Q000138:chemical synthesis*
D000480:Alkynes; D007202:Indicators and Reagents; D007659:Ketones; D011753:Pyrones; D012821:Silanes; D002248:Carbon Monoxide; D012428:Ruthenium