title: Antimicrobial bioassay of Colchicum luteum Baker.
abstract: The methanolic extract of the corms of Colchicum luteum Baker (Liliaceae) and its subsequent fractions in different solvent systems were screened for antibacterial and antifungal activities. The crude extract and all the fractions demonstrated moderate to excellent antifungal activities against tested pathogens in antifungal bioassay. Excellent antifungal activity was shown against trichophyton longifusus, up to 75%, and microsporum canis, up to 85%, while the crude extract and subsequent fractions showed mild to moderate activities in an antibacterial bioassay with maximum antibacterial activity 58% against Bacillus subtilis.
authors.affiliation: Department of Pharmacy, University of Peshawar, Pakistan. bashirdr2001@yahoo.com
authors.forename: Bashir
authors.initials: B
authors.lastname: Ahmad
authors.forename: Haroon
authors.initials: H
authors.lastname: Khan
authors.forename: Shumaila
authors.initials: S
authors.lastname: Bashir
authors.forename: Murad
authors.initials: M
authors.lastname: Ali
mesh_terms: D000890:Anti-Infective Agents / Q000494:pharmacology*; D001681:Biological Assay; D003079:Colchicum / Q000737:chemistry*; D000432:Methanol / Q000737:chemistry; D010936:Plant Extracts / Q000494:pharmacology
chemical_list: D000890:Anti-Infective Agents; D010936:Plant Extracts; D000432:Methanol