Brain plasticity and recovery from early cortical injury.
There is a general view that early brain damage leads to a far better outcome than damage later in life. Although there is a grain of truth to this idea, the reality is far more complex. We have identified a set of nine principles that underlie behavioral and anatomical changes after neonatal cortical injury as well as describing a variety of pre- and postnatal factors that modulate brain and behavioral plasticity after neonatal cortical lesions.
Kolb
Bryan
B
Canadian Centre for Behavioural Neuroscience, University of Lethbridge, Lethbridge, Alberta, Canada T1K 3M4. Kolb@uleth.ca
Gibb
Robbin
R
D000367:Age Factors; D000818:Animals; D001921:Brain / Q000502:physiology*; D001930:Brain Injuries / Q000503:physiopathology*; D002540:Cerebral Cortex / Q000503:physiopathology*; D003712:Dendrites / Q000502:physiology; D009473:Neuronal Plasticity / Q000502:physiology*; D051381:Rats; D020127:Recovery of Function