Sterically bulky tris(triazolyl)borate ligands as water-soluble analogues of tris(pyrazolyl)borate.
The recently synthesized 3-tert-butyl-5-methyl-1,2,4-triazole reacted with KBH4 to give the new potassium tris(3-tert-butyl-5-methyl-1,2,4-triazolyl)borate K(Ttz(tBu,Me)) ligand. Ttz(tBu,Me) formed a four-coordinate (Ttz(tBu,Me))CoCl complex and five-coordinate (Ttz(tBu,Me))CoNO3 and (Ttz(tBu,Me))ZnOAc complexes. When these complexes were compared to their Tp(tBu,Me) analogues, it was found that Ttz(tBu,Me) resulted in negligible steric differences. K(Ttz(tBu,Me)) is more water-soluble than K(Tp(tBu,Me)), so bulky tris(triazolyl)borate ligands should lead to functional models for enzyme active sites in an aqueous environment and the creation of water-soluble analogues of Tp catalysts.
Jernigan
Finith E
FE
Department of Chemistry, Salisbury University, Salisbury, Maryland 21801, USA.
Sieracki
Nathan A
NA
Taylor
Michael T
MT
Jenkins
Aaron S
AS
Engel
Sharon E
SE
Rowe
Brittany W
BW
Jové
Fernando A
FA
Yap
Glenn P A
GP
Papish
Elizabeth T
ET
Ferrence
Gregory M
GM