Megastigmanes and their glucosides from the whole plant of Sedum sarmentosum.
Two new megastigmanes, sarmentoic acid (1) and sarmentol A (2), and six new megastigmane glucosides, sedumosides A1 (3), A2 (4), A3 (5), B (6), C (7), and D (8), were isolated from the whole plant of Sedum sarmentosum together with eight known megastigmanes (9-16). The absolute stereostructures of 1-8 were elucidated on the basis of chemical and physicochemical evidence, including the application of the modified Mosher's method.
Yoshikawa
Masayuki
M
Kyoto Pharmaceutical University, Misasagi, Yamashina-ku, Kyoto 607-8412, Japan. myoshika@mb.kyoto-phn.ac.jp
Morikawa
Toshio
T
Zhang
Yi
Y
Nakamura
Seikou
S
Muraoka
Osamu
O
Matsuda
Hisashi
H
D003512:Cyclohexanones / Q000737:chemistry / Q000302:isolation & purification*; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification*; D005960:Glucosides / Q000737:chemistry / Q000302:isolation & purification*; D015394:Molecular Structure; D045792:Norisoprenoids / Q000737:chemistry / Q000302:isolation & purification*; D010946:Plants, Medicinal / Q000737:chemistry*; D031963:Sedum / Q000737:chemistry*
D003512:Cyclohexanones; D004365:Drugs, Chinese Herbal; D005960:Glucosides; D045792:Norisoprenoids; C413264:megastigmane; C519743:sarmentoic acid; C519744:sarmentol A