Novel metabolism in Chlamydomonas through the lens of genomics.
Chlamydomonas has traditionally been exploited as an organism that is associated with sophisticated physiological, genetic and molecular analyses, all of which have been used to elucidate several biological processes, especially photosynthesis and flagella function and assembly. Recently, the genomics of Chlamydomonas has been combined with other technologies to unveil new aspects of metabolism, including inorganic carbon utilization, anaerobic fermentation, the suite and functions of selenoproteins, and the regulation of vitamin biosynthesis. These initial findings represent the first glimpse through a genomic window onto the highly complex metabolisms that characterize a unicellular, photosynthetic eukaryote that has maintained both plant-like and animal-like characteristics over evolutionary time.
Grossman
Arthur R
AR
Department of Plant Biology, The Carnegie Institution, 260 Panama Street, Stanford, California 94305, USA. arthurg@stanford.edu
Croft
Martin
M
Gladyshev
Vadim N
VN
Merchant
Sabeeha S
SS
Posewitz
Matthew C
MC
Prochnik
Simon
S
Spalding
Martin H
MH
D000818:Animals; D002696:Chlamydomonas / Q000235:genetics* / Q000378:metabolism*; D015723:Gene Library; D016678:Genome; D023281:Genomics