title: Orexins: looking forward to sleep, back at addiction.
authors.forename: Thomas E
authors.initials: TE
authors.lastname: Scammell
authors.forename: Clifford B
authors.initials: CB
authors.lastname: Saper
mesh_terms: D006801:Humans; D007034:Hypothalamus, Posterior / Q000187:drug effects* / Q000378:metabolism; D047908:Intracellular Signaling Peptides and Proteins / Q000378:metabolism* / Q000502:physiology; D009479:Neuropeptides / Q000378:metabolism* / Q000502:physiology; D064446:Orexin Receptors; D000068797:Orexins; D043562:Receptors, G-Protein-Coupled / Q000037:antagonists & inhibitors*; D018013:Receptors, Neuropeptide / Q000037:antagonists & inhibitors*; D015398:Signal Transduction / Q000187:drug effects* / Q000502:physiology; D012893:Sleep Wake Disorders / Q000188:drug therapy*
chemical_list: D047908:Intracellular Signaling Peptides and Proteins; D009479:Neuropeptides; D064446:Orexin Receptors; D000068797:Orexins; D043562:Receptors, G-Protein-Coupled; D018013:Receptors, Neuropeptide