Cytogenetic mapping of DGAT1, PPARA, ADIPOR1 and CREB genes in the pig.
In the present study we show FISH localization of 4 porcine BAC clones harbouring potential candidate genes for fatness traits: DGAT1 (SSC4p15), PPARA (SSC5p15), ADIPOR1 (SSC10p13) and CREB (SSC15q24). Until now the CREB and ADIPOR1 genes are considered to be monomorphic, DGAT1 is highly polymorphic, while for the PPARA gene only 1 SNP was identified. Assignment of the studied genes in relation to QTL chromosome regions for meat quality in pig chromosomes SSC4, SSC5, SSC10 and SSC15 is discussed.
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Department of Genetics and Animal Breeding, August Cieszkowski Agricultural University of Poznań, Poland.
Lin
Li
L
Stachowiak
Monika
M
Chmurzynska
Agata
A
Mackowski
Mariusz
M
Winter
Andreas
A
Flisikowski
Krzysztof
K
Fries
Ruedi
R
Switonski
Marek
M
D052242:Adiponectin / Q000378:metabolism; D000818:Animals; D001483:Base Sequence; D002874:Chromosome Mapping / Q000662:veterinary; D022202:Chromosomes, Artificial, Bacterial / Q000235:genetics; D017362:Cyclic AMP Response Element-Binding Protein / Q000235:genetics*; D003582:Cytogenetics; D017931:DNA Primers / Q000235:genetics; D051048:Diacylglycerol O-Acyltransferase / Q000235:genetics*; D017404:In Situ Hybridization, Fluorescence; D047493:PPAR alpha / Q000235:genetics*; D011956:Receptors, Cell Surface / Q000235:genetics; D034421:Sus scrofa / Q000235:genetics*
D052242:Adiponectin; D017362:Cyclic AMP Response Element-Binding Protein; D017931:DNA Primers; D047493:PPAR alpha; D011956:Receptors, Cell Surface; D051048:Diacylglycerol O-Acyltransferase