title: Polymyositis--an unusual presentation of cGvHD in children.
abstract: Polymyositis is a rare manifestation of cGvHD in adult patients following allogeneic BMT. Here, we report on a 2.1-yr-old girl who presented with a facial swelling and rapidly developing respiratory failure eight months after BMT for severe combined immunodeficiency. Possible infectious agents and autoimmune origin other than cGvHD were excluded. The girl responded promptly to steroid therapy and remains well without other signs of cGvHD four months later.
authors.affiliation: Pediatrics and Adolescent Medicine, University of Freiburg, Freiburg, Germany. ruth.klein@uniklinik.freiburg.de
authors.forename: R
authors.initials: R
authors.lastname: Klein
authors.forename: P
authors.initials: P
authors.lastname: Franck
authors.forename: S
authors.initials: S
authors.lastname: Ehl
authors.forename: A
authors.initials: A
authors.lastname: Schmitt-Graeff
authors.forename: U
authors.initials: U
authors.lastname: Duffner
authors.forename: C M
authors.initials: CM
authors.lastname: Niemeyer
mesh_terms: D002675:Child, Preschool; D003402:Creatine Kinase / Q000097:blood; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D006086:Graft vs Host Disease / Q000150:complications* / Q000175:diagnosis*; D006801:Humans; D017285:Polymyositis / Q000097:blood / Q000188:drug therapy / Q000209:etiology*; D011239:Prednisolone / Q000627:therapeutic use; D016511:Severe Combined Immunodeficiency / Q000601:surgery
chemical_list: D005938:Glucocorticoids; D011239:Prednisolone; D003402:Creatine Kinase