title: Reversible glutathiolation of caspase-3 by glutaredoxin as a novel redox signaling mechanism in tumor necrosis factor-alpha-induced cell death.
authors.forename: Michelle C
authors.initials: MC
authors.lastname: Sykes
authors.forename: Amy L
authors.initials: AL
authors.lastname: Mowbray
authors.forename: Hanjoong
authors.initials: H
authors.lastname: Jo
mesh_terms: D000818:Animals; D017209:Apoptosis / Q000502:physiology*; D053148:Caspase 3 / Q000378:metabolism* / Q000502:physiology; D053181:Caspase 8 / Q000378:metabolism; D004792:Enzyme Precursors / Q000378:metabolism* / Q000502:physiology; D054477:Glutaredoxins; D005978:Glutathione / Q000378:metabolism*; D006801:Humans; D048031:JNK Mitogen-Activated Protein Kinases / Q000378:metabolism; D020935:MAP Kinase Signaling System / Q000502:physiology; D016328:NF-kappa B / Q000378:metabolism; D010084:Oxidation-Reduction; D010088:Oxidoreductases / Q000502:physiology*; D015398:Signal Transduction / Q000502:physiology*; D014409:Tumor Necrosis Factor-alpha / Q000502:physiology*
chemical_list: D004792:Enzyme Precursors; D054477:Glutaredoxins; D016328:NF-kappa B; D014409:Tumor Necrosis Factor-alpha; D010088:Oxidoreductases; D048031:JNK Mitogen-Activated Protein Kinases; D053148:Caspase 3; D053181:Caspase 8; D005978:Glutathione