title: Changes in multifocal oscillatory potentials after internal limiting membrane removal for macular hole: multifocal OPs after ILM removal.
abstract: OBJECTIVE
  To determine whether removal of the internal limiting membrane (ILM) during macular hole (MH) surgery alters the retinal function.
  
  
  METHODS
  Multifocal electroretinograms (mfERGs) were recorded preoperatively and 3 months after surgery from 11 eyes of 10 patients with an idiopathic MH treated successfully by pars plana vitrectomy accompanied by ILM removal. A low frequency (9.4 Hz) pseudorandom binary m-sequence stimulus was used to elicit the mfERGs from different retinal loci. The bandpass of the amplifier was set at 10-300 Hz to record the mfERGs and at 100-300 Hz to record the oscillatory potentials (OPs).
  
  
  RESULTS
  An anatomical closure of the MH was achieved in all patients, and the mean visual acuity was significantly improved postoperatively. No significant difference was observed in both the amplitudes and implicit times of the negative and positive waves of the mfERGs and the OPs recorded preoperatively to those recorded postoperatively.
  
  
  CONCLUSIONS
  MH surgery with ILM removal does not alter the electrophysiological function of both the outer and inner retina of the posterior pole where the ILM was removed.
authors.affiliation: Department of Ophthalmology and Visual Science, Chiba University Graduate School of Medicine, Chiba, Japan.
authors.forename: Kazuha
authors.initials: K
authors.lastname: Ogata
authors.forename: Shuichi
authors.initials: S
authors.lastname: Yamamoto
authors.forename: Yoshinori
authors.initials: Y
authors.lastname: Mitamura
authors.forename: Takeshi
authors.initials: T
authors.lastname: Sugawara
authors.forename: Satoshi
authors.initials: S
authors.lastname: Mizunoya
mesh_terms: D000368:Aged; D004585:Electrooculography; D005074:Evoked Potentials, Visual / Q000502:physiology*; D005500:Follow-Up Studies; D006801:Humans; D008266:Macula Lutea / Q000503:physiopathology*; D008875:Middle Aged; D011184:Postoperative Period; D012167:Retinal Perforations / Q000503:physiopathology* / Q000601:surgery; D016896:Treatment Outcome; D014821:Vitrectomy / Q000379:methods*