title: Circulating human monocytes in the acute coronary syndrome express a characteristic proteomic profile.
abstract: We examined the proteome of circulating monocytes of patients with acute coronary syndrome at different times in comparison to that of patients with stable coronary artery disease. On admission, the expression of 18 spot proteins was altered, 10 of which were totally absent. This pattern changed progressively, and at 6 months, there were no differences with the monocyte proteome of stable patients.
authors.affiliation: Department of Immunology, Fundación Jiménez Díaz, Avenida Reyes Católicos 2, 28040 Madrid, Spain.
authors.forename: María G
authors.initials: MG
authors.lastname: Barderas
authors.forename: José
authors.initials: J
authors.lastname: Tuñón
authors.forename: Verónica M
authors.initials: VM
authors.lastname: Dardé
authors.forename: Fernando
authors.initials: F
authors.lastname: De la Cuesta
authors.forename: María C
authors.initials: MC
authors.lastname: Durán
authors.forename: José J
authors.initials: JJ
authors.lastname: Jiménez-Nácher
authors.forename: Nieves
authors.initials: N
authors.lastname: Tarín
authors.forename: Lorenzo
authors.initials: L
authors.lastname: López-Bescós
authors.forename: Jesús
authors.initials: J
authors.lastname: Egido
authors.forename: Fernando
authors.initials: F
authors.lastname: Vivanco
mesh_terms: D000368:Aged; D001798:Blood Proteins / Q000378:metabolism*; D017023:Coronary Angiography; D003327:Coronary Disease / Q000097:blood* / Q000000981:diagnostic imaging; D004798:Enzymes / Q000097:blood; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009000:Monocytes / Q000473:pathology*; D018579:Patient Selection; D040901:Proteomics / Q000379:methods*; D021241:Spectrometry, Mass, Electrospray Ionization; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
chemical_list: D001798:Blood Proteins; D004798:Enzymes