title: The raphe magnus/pallidus regulates sweat secretion and skin vasodilation of the cat forepaw pad: a preliminary electrical stimulation study.
abstract: In the human palm/sole, mental or physical stimuli induce an increase in sweat secretion and a decrease in skin blood flow (SkBF). However, the central pathways of these responses remain unclear. We measured sweat secretion and SkBF in the cat footpad by electrically stimulating the raphe. Stimulation of the rostral raphe magnus/pallidus elicited a reduction in SkBF without affecting sweat secretion. Stimulation of the mid to caudal raphe magnus/pallidus elicited an increase in both sweat secretion and SkBF. The raphe magnus/pallidus may play a crucial role in skin vasomotor and sudomotor responses in the cat footpad.
authors.affiliation: Department of Neurology, Chiba University School of Medicine, 1-8-1 Inohana, Chuo-ku, Chiba 260-8670, Japan. asahina@faculty.chiba-u.jp
authors.forename: Masato
authors.initials: M
authors.lastname: Asahina
authors.forename: Ryuji
authors.initials: R
authors.lastname: Sakakibara
authors.forename: Zhi
authors.initials: Z
authors.lastname: Liu
authors.forename: Takashi
authors.initials: T
authors.lastname: Ito
authors.forename: Yoshitaka
authors.initials: Y
authors.lastname: Yamanaka
authors.forename: Ken
authors.initials: K
authors.lastname: Nakazawa
authors.forename: Eiji
authors.initials: E
authors.lastname: Shimizu
authors.forename: Takamichi
authors.initials: T
authors.lastname: Hattori
mesh_terms: D000818:Animals; D017776:Autonomic Pathways / Q000502:physiology; D001833:Body Temperature Regulation / Q000502:physiology; D002415:Cats; D004525:Efferent Pathways / Q000502:physiology; D004558:Electric Stimulation; D005552:Forelimb / Q000098:blood supply / Q000294:innervation*; D008297:Male; D008526:Medulla Oblongata / Q000033:anatomy & histology / Q000502:physiology; D008833:Microcirculation / Q000294:innervation* / Q000502:physiology; D011903:Raphe Nuclei / Q000033:anatomy & histology / Q000502:physiology*; D012039:Regional Blood Flow / Q000502:physiology; D012867:Skin / Q000098:blood supply / Q000294:innervation*; D013545:Sweat Glands / Q000294:innervation* / Q000378:metabolism; D013546:Sweating / Q000502:physiology; D014664:Vasodilation / Q000502:physiology*; D014666:Vasomotor System / Q000502:physiology