title: Species-specific differences in the susceptibilities of biofilms formed by Candida bloodstream isolates to echinocandin antifungals.
abstract: The echinocandin susceptibilities of bloodstream Candida isolates growing in a biofilm was investigated. Within the therapeutic range of concentrations of each drug, caspofungin and micafungin were active against biofilms formed by Candida albicans or C. glabrata but not those formed by C. tropicalis or C. parapsilosis.
authors.affiliation: Department of Laboratory Medicine, Chonnam National University Medical School, 8 Hakdong Dongku, Gwangju 501-757, South Korea.
authors.forename: Hyun Woo
authors.initials: HW
authors.lastname: Choi
authors.forename: Jong Hee
authors.initials: JH
authors.lastname: Shin
authors.forename: Sook In
authors.initials: SI
authors.lastname: Jung
authors.forename: Kyung Hwa
authors.initials: KH
authors.lastname: Park
authors.forename: Duck
authors.initials: D
authors.lastname: Cho
authors.forename: Seung Jung
authors.initials: SJ
authors.lastname: Kee
authors.forename: Myung Geun
authors.initials: MG
authors.lastname: Shin
authors.forename: Soon Pal
authors.initials: SP
authors.lastname: Suh
authors.forename: Dong Wook
authors.initials: DW
authors.lastname: Ryang
mesh_terms: D000935:Antifungal Agents / Q000494:pharmacology*; D018441:Biofilms / Q000187:drug effects* / Q000254:growth & development; D001769:Blood / Q000382:microbiology*; D002175:Candida / Q000145:classification / Q000187:drug effects* / Q000254:growth & development / Q000302:isolation & purification; D002177:Candidiasis / Q000188:drug therapy; D054714:Echinocandins; D005656:Fungal Proteins / Q000494:pharmacology*; D008826:Microbial Sensitivity Tests; D010456:Peptides, Cyclic / Q000494:pharmacology*; D013045:Species Specificity
chemical_list: D000935:Antifungal Agents; D054714:Echinocandins; D005656:Fungal Proteins; D010456:Peptides, Cyclic; C007572:echinocandin B