title: Invasive amebiasis.
abstract: Digestive amoebiasis with his invasive form is an unusual pathology encountered in the temperate zone. This could lead to a life threatening complication: systemic amoebiasis. A 55-year-old male was treated successfully of systemic amoebiasis in a third referral hospital. The diagnosis was established based on epidemiology data and microscopical identification of trophozoites of Entamoeba histolytica. The amoebicidal, antibiotic and supportive treatments was firstly administrated. The clinical picture of intestinal amoebiasis raised from dysenteric syndrome to necrotizing enteritis. The bowel perforation with localized peritonitis was followed by chronic enteric fistula. Amoebic liver abscess, as the most frequent extraintestinal complication, was concomitantly diagnosed and treated. Urinary amoebiasis was considered as complication in the context of systemic dissemination: any other location could become a site of an amoebic abscess. Multidisciplinary approach was the successful key in the management of the patient, including antiparasitic therapy and antibiotic prophylaxis, intensive care and multiple surgical approaches. The diagnosis of digestive amoebiasis and systemic complication may be delayed in nonendemic areas, leading to advanced and complicated stages of the disease. The surgical approach is most efficiently to treat a large liver amoebic abscess and intraperitoneal collections.
authors.affiliation: Third Surgical Unit, St. Spiridon Hospital of Iasi. fgrecu@zappmobile.ro
authors.forename: F
authors.initials: F
authors.lastname: Grecu
authors.forename: Teodora
authors.initials: T
authors.lastname: Bulgariu
authors.forename: Oana
authors.initials: O
authors.lastname: Blanaru
authors.forename: C
authors.initials: C
authors.lastname: Dragomir
authors.forename: Claudia
authors.initials: C
authors.lastname: Lunca
authors.forename: I
authors.initials: I
authors.lastname: Stratan
authors.forename: Carmen
authors.initials: C
authors.lastname: Manciuc
authors.forename: V
authors.initials: V
authors.lastname: Luca
mesh_terms: D000563:Amebicides / Q000627:therapeutic use; D000818:Animals; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use; D000981:Antiprotozoal Agents / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D004748:Entamoeba histolytica / Q000302:isolation & purification; D004749:Entamoebiasis / Q000175:diagnosis / Q000469:parasitology / Q000628:therapy*; D006801:Humans; D007079:Ileitis / Q000175:diagnosis / Q000469:parasitology / Q000628:therapy*; D007412:Intestinal Fistula / Q000175:diagnosis / Q000469:parasitology / Q000628:therapy*; D008101:Liver Abscess, Amebic / Q000175:diagnosis / Q000469:parasitology / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D012086:Reoperation; D013396:Suction; D016896:Treatment Outcome
chemical_list: D000563:Amebicides; D000900:Anti-Bacterial Agents; D000935:Antifungal Agents; D000981:Antiprotozoal Agents