Panhypopituitarism as first manifestation of a lung cancer.
Pituitary metastases of solid tumours are infrequent, specially as a first manifestation. When they happen, they are usually due to breast or lung cancer and are asymptomatic or produce diabetes insipidus. It is very strange that they produce hormonal deficiency. We present a case report of a bronchogenic adenocarcinoma in a 65-year-old man which began with panhypopituitarism, diabetes insipidus and visual alterations. Magnetic resonance imaging revealed a large sellar mass, with clivus infiltration and invading the right cavernous sinus. The biopsy result was adenocarcinoma metastases from lung cancer.
Guillén Ponce
Carmen
C
Servicio de Oncología Médica, Hospital General Universitario de Elche, Alicante, Spain. carmenguillenponce@yahoo.es
Garrido López
María Pilar
MP
Molina Garrido
María José
MJ
Muñoz Molina
Gema
G
Carrato
Alfredo
A
D000230:Adenocarcinoma / Q000150:complications* / Q000556:secondary*; D000368:Aged; D006801:Humans; D007018:Hypopituitarism / Q000209:etiology*; D008175:Lung Neoplasms / Q000473:pathology*; D008297:Male; D010911:Pituitary Neoplasms / Q000150:complications* / Q000556:secondary*