Paroxysmal nocturnal hemoglobinuria: complete resolution of an occluding inferior vena caval thrombus.
Paroxysmal nocturnal hemoglobinuria is a rare acquired autoimmune disease, and is frequently associated with venous thrombosis. A patient who developed thrombotic occlusion of the inferior vena cava is described. Treatment with heparin and urokinase, followed by oral anticoagulant, was effective in resolving abdominal symptoms. The venous thrombosis resolved completely, but the patient died during treatment of aplastic anemia.
Shindo
Shunya
S
Second Department of Surgery, Faculty of Medicine, University of Yamanashi, 1110 Shimokato, Chuo City, Yamanashi, 409-3898, Japan. sshindo@yamanashi.ac.jp
Motohashi
Shinya
S
Kaga
Shigeaki
S
Inoue
Hidenori
H
Matsumoto
Masahiko
M
Shindo
Hiroo
H
D000328:Adult; D003937:Diagnosis, Differential; D003952:Diagnostic Imaging; D017809:Fatal Outcome; D005260:Female; D006457:Hemoglobinuria, Paroxysmal / Q000150:complications*; D006801:Humans; D015912:Thrombolytic Therapy; D014682:Vena Cava, Inferior; D020246:Venous Thrombosis / Q000175:diagnosis* / Q000188:drug therapy