title: [Hepatitis C virus: biology, immunopathogenesis, and NK/NKT cells during viral persistence].
abstract: Data on immunological changes that accompanied HCV infection are analyzed. Role of various viral proteins in induction of immune alterations leading to HCV persistence is reviewed. Possibility of association between pathogenic mechanisms (and outcomes) of hepatitis C and alteration of aminergic regulation mechanisms in the immune system as well as perspectives of further studies assessing the role NK and NKT cell in this process.
authors.forename: R I
authors.initials: RI
authors.lastname: Sepiashvili
authors.forename: I P
authors.initials: IP
authors.lastname: Balmasova
authors.forename: E V
authors.initials: EV
authors.lastname: Kabanova
authors.forename: E S
authors.initials: ES
authors.lastname: Malova
authors.forename: E V
authors.initials: EV
authors.lastname: Pleskanovskaia
mesh_terms: D001679:Biogenic Amines / Q000378:metabolism; D015536:Down-Regulation; D016174:Hepacivirus / Q000502:physiology*; D006526:Hepatitis C / Q000276:immunology* / Q000821:virology; D019698:Hepatitis C, Chronic / Q000276:immunology / Q000503:physiopathology; D006801:Humans; D007694:Killer Cells, Natural / Q000276:immunology*; D008099:Liver / Q000276:immunology / Q000473:pathology; D016131:Lymphocyte Subsets / Q000276:immunology*; D014779:Virus Replication
chemical_list: D001679:Biogenic Amines