title: Clostridium cadaveris septic arthritis after total hip arthroplasty in a metastatic breast cancer patient.
abstract: We report the first known case of septic arthritis in the setting of total hip arthroplasty caused by Clostridium cadaveris, a gas-forming anaerobic enteric organism usually considered a non-pathogen. This case occurred in a patient treated with total hip arthroplasty for metastatic breast cancer involving the acetabulum. The patient was managed successfully with debridement, prosthetic retention, and chronic antibiotic suppression. We propose this mode of care as a successful alternative for some patients with prosthetic joint infection and prohibitive comorbid conditions.
authors.affiliation: Department of Orthopaedic Surgery, Orthopaedic Oncology Service, UCSF Comprehensive Cancer Center, San Francisco, California 94115, USA.
authors.forename: Saam
authors.initials: S
authors.lastname: Morshed
authors.forename: Farbod
authors.initials: F
authors.lastname: Malek
authors.forename: Robert M
authors.initials: RM
authors.lastname: Silverstein
authors.forename: Richard J
authors.initials: RJ
authors.lastname: O'Donnell
mesh_terms: D000077:Acetabulum / Q000473:pathology* / Q000601:surgery*; D000890:Anti-Infective Agents / Q000627:therapeutic use; D001170:Arthritis, Infectious / Q000382:microbiology* / Q000628:therapy*; D019644:Arthroplasty, Replacement, Hip; D001859:Bone Neoplasms / Q000556:secondary* / Q000601:surgery*; D001943:Breast Neoplasms / Q000473:pathology*; D003015:Clostridium Infections / Q000382:microbiology / Q000628:therapy*; D003646:Debridement; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D008875:Middle Aged
chemical_list: D000890:Anti-Infective Agents