title: [An interactive method for optimization of irradiation plans in radiation therapy of malignant tumors].
abstract: Formation of a rational dose filed in contact radiation therapy of malignant tumors is, in the majority of cases, a multicriterion and multiextremal problem. A compromise plan of irradiation can be obtained by interactive matching of alternative criteria of radiation therapy. In this work, it is suggested to solve the problem of formation of effective therapeutic dose fields using synthesized methods, including modified trial-and-error method (visual optimization method), and mathematical programming methods. This combined approach provides better opportunities for formation of effective therapeutic dose fields in radiation therapy of malignant tumors.
authors.forename: L Ia
authors.initials: LIa
authors.lastname: Klepper
mesh_terms: D004307:Dose-Response Relationship, Radiation; D006801:Humans; D008433:Mathematics; D008962:Models, Theoretical; D009369:Neoplasms / Q000532:radiotherapy*; D011880:Radiotherapy Planning, Computer-Assisted / Q000379:methods*