title: Minor depression and health status among US adults with diabetes mellitus.
abstract: OBJECTIVE
  To determine whether diabetes mellitus (DM) with minor depression is associated with poorer levels of mental and physical functioning compared with DM without depression.
  
  
  METHODS
  Retrospective database study.
  
  
  METHODS
  US adults participating in the 2001 Medical Expenditure Panel Survey were included in these analyses. Main outcome measures were differences in health status, physical and cognitive limitations, and the Short-Form 12 (SF-12) Mental Component Summary (MCS) and Physical Component Summary (PCS) for US adults with DM stratified by minor depression status and evaluated using univariate and multivariate analyses to control for demographic, behavioral, and clinical covariates.
  
  
  RESULTS
  A total of 1572 respondents with DM were included (1443 without depression, 129 with depression). Compared with people with DM and without depression, those with DM and minor depression were younger (P = .04); were more likely to be female, white, and smokers; and to have physical and cognitive limitations and lower SF-12 MCS and PCS scores (all P < .01). In multivariate analyses, minor depression was independently associated with lower self-reported health status, MCS scores, and more cognitive limitations.
  
  
  CONCLUSIONS
  People with DM and minor depression have lower mental functional scores, more cognitive limitations, and lower self-reported health status scores compared with people with DM and without depression, differences that may adversely affect self-care activities. Primary and DM care providers should screen for and be aware of depression in their patients with DM.
authors.affiliation: University of Colorado at Denver and Health Sciences Center, School of Pharmacy, Denver, CO 80262, USA. marianne.mccollum@uchsc.edu
authors.forename: Marianne
authors.initials: M
authors.lastname: McCollum
authors.forename: Samuel L
authors.initials: SL
authors.lastname: Ellis
authors.forename: Judith G
authors.initials: JG
authors.lastname: Regensteiner
authors.forename: Weiming
authors.initials: W
authors.lastname: Zhang
authors.forename: Patrick W
authors.initials: PW
authors.lastname: Sullivan
mesh_terms: D000203:Activities of Daily Living; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003072:Cognition Disorders / Q000209:etiology; D016208:Databases, Factual; D003863:Depression / Q000145:classification / Q000150:complications* / Q000191:economics; D048909:Diabetes Complications / Q000453:epidemiology; D003920:Diabetes Mellitus / Q000453:epidemiology / Q000523:psychology*; D005260:Female; D024841:Fluoroquinolones; D006304:Health Status; D006801:Humans; D007182:Income; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D011795:Surveys and Questionnaires; D014481:United States / Q000453:epidemiology
chemical_list: D024841:Fluoroquinolones; C053091:lomefloxacin