Long-term outcome of bilateral pallidal deep brain stimulation for primary cervical dystonia.
Ten patients with severe cervical dystonia (CD) unresponsive to medical treatment underwent bilateral globus pallidus internus (GPi) deep brain stimulation (DBS) and were followed for 31.9 +/- 20.9 months. At last follow-up, the Toronto Western Spasmodic Torticollis Rating Scale (TWSTRS) severity score improved by 54.8%, the TWSTRS disability score improved by 59.1%, and the TWSTRS pain score improved by 50.4%. Bilateral GPi DBS is an effective long-term therapy in patients with CD.
Hung
S W
SW
Movement Disorders Centre, Division of Neurology, Toronto Western Hospital, University of Toronto, Toronto, Ontario, Canada M5T 2S8.
Hamani
C
C
Lozano
A M
AM
Poon
Y-Y W
YY
Piboolnurak
P
P
Miyasaki
J M
JM
Lang
A E
AE
Dostrovsky
J O
JO
Hutchison
W D
WD
Moro
E
E
D000328:Adult; D000368:Aged; D046690:Deep Brain Stimulation / Q000379:methods*; D005260:Female; D005917:Globus Pallidus; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D014103:Torticollis / Q000175:diagnosis* / Q000628:therapy*; D016896:Treatment Outcome