title: Vaginal cancer in a patient treated for cervical intraepithelial neoplasia (CIN 3): case report.
abstract: In 1% to 3% of patients with cervical intraepithelial neoplasia (CIN), vaginal intraepithelial neoplasia (VAIN) will either coexist or occur at a later date. The time interval from an earlier diagnosis of CIN 3 to a current diagnosis of VAIN 3 varies from two to 17 years. Invasive vaginal cancer occurred in a woman five years after total abdominal hysterectomy for cervical intraepithelial neoplasia. In women who have undergone total hysterectomy for cervical intraepithelial neoplasia or cervical cancer, postoperative cytologic and colposcopic follow-up of the vagina is necessary.
authors.affiliation: Department of Obstetrics and Gynecology, Patras University Hospital, Rion, Greece.
authors.forename: G
authors.initials: G
authors.lastname: Androutsopoulos
authors.forename: G
authors.initials: G
authors.lastname: Adonakis
authors.forename: P
authors.initials: P
authors.lastname: Ravazoula
authors.forename: G
authors.initials: G
authors.lastname: Kourounis
mesh_terms: D000328:Adult; D001918:Brachytherapy; D002278:Carcinoma in Situ / Q000473:pathology* / Q000532:radiotherapy / Q000601:surgery; D003127:Colposcopy; D005260:Female; D006801:Humans; D007044:Hysterectomy; D018307:Neoplasms, Squamous Cell / Q000473:pathology* / Q000532:radiotherapy / Q000601:surgery; D013997:Time Factors; D002583:Uterine Cervical Neoplasms / Q000473:pathology* / Q000601:surgery; D014621:Vagina / Q000601:surgery; D014625:Vaginal Neoplasms / Q000473:pathology* / Q000532:radiotherapy / Q000601:surgery; D002578:Uterine Cervical Dysplasia / Q000473:pathology* / Q000601:surgery