New approach in asthma treatment using excitatory modulator.
The impact of a herbal extract with excitatory modulator activity in the management of asthma was studied. An open and selective 3-year follow-up of 14 chronic refractory asthmatics aged between 22 and 70 was used. Participants received an extract of Sophora flavescens Ait. Medication use, a diary card of symptoms and respiratory function were recorded. The study was retrospective and all patients gave written informed consent. The quality of life, clinical symptoms and respiratory function improved during all periods of measurement. The use of inhaled corticosteroid and beta-agonists were reduced or eliminated. There were no significant adverse reactions reported. Therefore the extract of S. flavescens as an excitatory modulator appears to be a safe and may be an effective alternative treatment for refractory chronic asthma.
Hoang
Ba X
BX
Hoang Allergy Research Group 4010 Moorpark Ave, Ste 119 San Jose CA95117, USA. niscba@aol.com
Shaw
D Graeme
DG
Levine
Stephen
S
Hoang
Cuong
C
Pham
Phuong
P
D000328:Adult; D000368:Aged; D018927:Anti-Asthmatic Agents / Q000008:administration & dosage / Q000737:chemistry / Q000627:therapeutic use*; D001249:Asthma / Q000188:drug therapy*; D002851:Chromatography, High Pressure Liquid; D007887:Fabaceae / Q000737:chemistry*; D005500:Follow-Up Studies; D006801:Humans; D008875:Middle Aged; D008517:Phytotherapy / Q000379:methods; D010936:Plant Extracts / Q000008:administration & dosage / Q000737:chemistry / Q000627:therapeutic use*; D012189:Retrospective Studies; D016896:Treatment Outcome
D018927:Anti-Asthmatic Agents; D010936:Plant Extracts