title: Bone grafting with platelet-rich plasma in alveolar cleft. Case report.
abstract: Bone grafting of the alveolus has become an essential part of the contemporary surgical management of oral clefts. The benefits of this procedure are the stabilization of the maxillary arch, elimination of oronasal fistulae, the reconstruction of the soft tissue nasal base support, creation of bony support for subsequent tooth eruption or, when they are not present or not preserved, for implants application. The authors show a case of bone grafting with the aid of platelet-rich plasma (PRP). Because of the difficulties due to the oral cleft and to its surgical reparation (big size of bone defect, hard scars and sclerotic soft tissue) the authors decided to add PRP to a bone graft taken from the chin. PRP contains a high concentration of growth factors and is able to stimulate both wound and bone regeneration. Infact, the authors have observed very good results both in bone integration and in soft tissue reparation.
authors.affiliation: Unit of Maxillofacial Surgery, Department of Odontostomatological, Orthodontic and Surgical Sciences, Second University of Naples, Naples, Italy. rosario.rullo@unina2.it
authors.forename: R
authors.initials: R
authors.lastname: Rullo
authors.forename: V M
authors.initials: VM
authors.lastname: Festa
authors.forename: L
authors.initials: L
authors.lastname: Guida
authors.forename: G
authors.initials: G
authors.lastname: Laino
mesh_terms: D000293:Adolescent; D000543:Alveoloplasty; D000848:Anodontia / Q000534:rehabilitation; D002971:Cleft Lip / Q000534:rehabilitation / Q000601:surgery; D002972:Cleft Palate / Q000534:rehabilitation / Q000601:surgery; D005260:Female; D005782:Gels; D006801:Humans; D007180:Incisor; D008334:Mandible / Q000637:transplantation*; D053657:Platelet-Rich Plasma; D013524:Surgical Flaps; D013917:Thrombin / Q000627:therapeutic use; D020390:Tooth Socket / Q000002:abnormalities / Q000601:surgery*; D014182:Transplantation, Autologous / Q000379:methods*
chemical_list: D005782:Gels; D013917:Thrombin