[Hepatitis C virus: biology, immunopathogenesis, and NK/NKT cells during viral persistence].
Data on immunological changes that accompanied HCV infection are analyzed. Role of various viral proteins in induction of immune alterations leading to HCV persistence is reviewed. Possibility of association between pathogenic mechanisms (and outcomes) of hepatitis C and alteration of aminergic regulation mechanisms in the immune system as well as perspectives of further studies assessing the role NK and NKT cell in this process.
Sepiashvili
R I
RI
Balmasova
I P
IP
Kabanova
E V
EV
Malova
E S
ES
Pleskanovskaia
E V
EV
D001679:Biogenic Amines / Q000378:metabolism; D015536:Down-Regulation; D016174:Hepacivirus / Q000502:physiology*; D006526:Hepatitis C / Q000276:immunology* / Q000821:virology; D019698:Hepatitis C, Chronic / Q000276:immunology / Q000503:physiopathology; D006801:Humans; D007694:Killer Cells, Natural / Q000276:immunology*; D008099:Liver / Q000276:immunology / Q000473:pathology; D016131:Lymphocyte Subsets / Q000276:immunology*; D014779:Virus Replication
D001679:Biogenic Amines