title: Neuronal dynamics of dynamic synapses.
abstract: This work presents a model of minimal time-continuous target-cell specific use-dependent short-term synaptic plasticity (STP) observed in the pyramidal cells that can account for both short-term depression and facilitation. In general it provides a concise and portable description that is useful for predicting synaptic responses to more complex patterns of simulation, for studies relating to circuit dynamics and for equating dynamic properties across different synaptic pathways between or within preparations. This model allows computation of postsynaptic responses by either facilitation or depression in the synapse thus exhibiting characteristics of dynamic synapses as that found during short-term synaptic plasticity, for any arbitrary pre-synaptic spike train in the presence of realistic background synaptic noise. Thus it allows us to see specific effect of the spike train on a neuronal lattice both small-scale and large-scale, so as to reveal the short-term plastic behavior in neurons.
authors.affiliation: Department of Computer Science & Psychology, University of York, York YO10 5DD, England. Email: sengupta@ieee.org.
authors.forename: Biswa
authors.initials: B
authors.lastname: Sengupta
authors.forename: David
authors.initials: D
authors.lastname: Halliday