[Pseudotumor cerebri with all-trans retinoic acid. A case report].
The diagnosis of pseudotumor cerebri (PC) is based on the triad of: (1) papilledema, (2) elevated intracranial pressure with a normal cerebrospinal constituency and (3) normal central nervous system imaging studies. It is an uncommon complication of all-trans-retinoic acid (ATRA) therapy in children treated for acute promyelocytic leukaemia (APL). Its occurrence is rare among adult patients with APL and treated with ATRA . We report a case of an adult with APL who developed PC during induction therapy with ATRA-PC was managed with repeated lumbar punctures and corticotherapy.
Jeddi
Ramzi
R
Service d'Hénmatologie clinique, Hôpital Aziza Othmnana.
Kacem
Karima
K
Ben Lakhal
Raihane
R
Aissaoui
Lamia
L
Ben Abid
Hela
H
Belhadj Ali
Zaher
Z
Meddeb
Balkis
B
D000328:Adult; D000970:Antineoplastic Agents / Q000009:adverse effects*; D005260:Female; D006801:Humans; D011559:Pseudotumor Cerebri / Q000139:chemically induced*; D014212:Tretinoin / Q000009:adverse effects*
D000970:Antineoplastic Agents; D014212:Tretinoin