title: [Dual-source cardiac CT imaging with improved temporal resolution: Impact on image quality and analysis of left ventricular function].
abstract: In a newly developed dual-source computed tomography system (DSCT) the relation of heart rate and image quality and the possible advantages of the system's superior temporal resolution in the evaluation of left ventricular parameters as compared to results of cardiac magnetic resonance imaging (MRI) were assessed. Coronary CT angiography was performed using a DSCT (Somatom Defintion, Siemens Medical Solutions, Forchheim, Germany) in 21 patients (mean age 62+/-8; 15 male, 6 female). Image quality of the coronary arteries, the heart valves, and the left ventricular myocardium was assessed using a three-point grading scale. Ten of these patients also underwent cardiac MRI for the assessment of left ventricular function, using a SSFP (steady-state free precession) sequence. Left ventricular ejection fractions (LV-EF), the end-systolic volumes (ESV), and the end-diastolic volumes (EDV) were measured employing MRI and DSCT datasets. The image quality ratings for the coronary arteries at the optimal reconstruction interval were diagnostic even in patients with high heart rates (1.42+/-0.49). Analysis of global LV function using DSCT quantified from CTA datasets showed a good correlation with results of cardiac MRI [EF: r=0.75 (p=0.01); ESV: r=0.72 (p=0.19); EDV: r=0.71 (p=0.02)]. The dual-source CT system offers robust image quality of the coronary arteries, independent of the heart rate, and provides combined diagnostic imaging of coronary arteries, the heart valves, the myocardium, and the global left ventricular function.
authors.affiliation: Institut für Klinische Radiologie, Klinikum Grosshadern der Ludwig-Maximilians-Universität München, Marchioninistrasse 15, 81377, München, Deutschland. carsten.rist@med.uni-muenchen.de
authors.forename: Carsten
authors.initials: C
authors.lastname: Rist
authors.forename: T R
authors.initials: TR
authors.lastname: Johnson
authors.forename: A
authors.initials: A
authors.lastname: Becker
authors.forename: A W
authors.initials: AW
authors.lastname: Leber
authors.forename: A
authors.initials: A
authors.lastname: Huber
authors.forename: S
authors.initials: S
authors.lastname: Busch
authors.forename: C R
authors.initials: CR
authors.lastname: Becker
authors.forename: M F
authors.initials: MF
authors.lastname: Reiser
authors.forename: K
authors.initials: K
authors.lastname: Nikolaou
mesh_terms: D017023:Coronary Angiography / Q000379:methods*; D003324:Coronary Artery Disease / Q000150:complications / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011856:Radiographic Image Enhancement / Q000379:methods*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed / Q000379:methods*; D018487:Ventricular Dysfunction, Left / Q000000981:diagnostic imaging* / Q000209:etiology