title: Janthinolide A-B, two new 2,5-piperazinedione derivatives from the endophytic Penicillium janthinellum isolated from the soft coral Dendronephthya sp.
abstract: Two new 2,5-piperazinedione derivatives, janthinolide A and B (1-2), along with deoxymycelianamide, griseofulvin and dechlorogriseofulvin were isolated from the fermentation broths of the endophytic fungus Penicillium janthinellum isolated from a soft coral, Dendronephthya sp. Their structures were established by extensive spectroscopic data analysis.
authors.affiliation: State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing, PR China.
authors.forename: Chunmei
authors.initials: C
authors.lastname: Xue
authors.forename: Tian
authors.initials: T
authors.lastname: Li
authors.forename: Zhiwei
authors.initials: Z
authors.lastname: Deng
authors.forename: Hongzheng
authors.initials: H
authors.lastname: Fu
authors.forename: Wenhan
authors.initials: W
authors.lastname: Lin
mesh_terms: D000818:Animals; D037421:Anthozoa / Q000382:microbiology*; D005285:Fermentation; D009682:Magnetic Resonance Spectroscopy; D009904:Optical Rotation; D010407:Penicillium / Q000737:chemistry*; D010879:Piperazines / Q000737:chemistry* / Q000302:isolation & purification; D021241:Spectrometry, Mass, Electrospray Ionization; D016339:Spectrometry, Mass, Fast Atom Bombardment; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet
chemical_list: D010879:Piperazines; C517900:janthinolide A; C517899:janthinolide B