title: Carbamazepine poisoning managed with haemodialysis and haemoperfusion in three adolescents.
abstract: Carbamazepine is a widely used antiepileptic agent. Accidental or suicidal overdose in children is not uncommon. Acute toxicity is associated with seizures, coma, arrhythmias and death in severe cases. Here we report three adolescents with carbamzepine overdose, two managed with standard low-flux haemodialysis and one with charcoal haemoperfusion. Our report emphasizes that haemodialysis might be a cheaper and easier alternative for carbamazepine overdose in milder cases, with fewer side-effects than haemoperfusion.
authors.affiliation: Department of Paediatric Nephrology, Faculty of Medicine, Ondokuz Mayis University, Samsun, Turkey. kenanbek2000@yahoo.com
authors.forename: Kenan
authors.initials: K
authors.lastname: Bek
authors.forename: Sule
authors.initials: S
authors.lastname: Koçak
authors.forename: Ozan
authors.initials: O
authors.lastname: Ozkaya
authors.forename: Yunus
authors.initials: Y
authors.lastname: Yilmaz
authors.forename: Omer Faruk
authors.initials: OF
authors.lastname: Aydin
authors.forename: Cigdem Sag
authors.initials: CS
authors.lastname: Taşdöven
mesh_terms: D000293:Adolescent; D000927:Anticonvulsants / Q000506:poisoning*; D002220:Carbamazepine / Q000506:poisoning*; D002606:Charcoal / Q000008:administration & dosage*; D002648:Child; D062787:Drug Overdose / Q000503:physiopathology / Q000628:therapy*; D005260:Female; D006464:Hemoperfusion; D006801:Humans; D007902:Length of Stay; D008297:Male; D006435:Renal Dialysis; D016896:Treatment Outcome
chemical_list: D000927:Anticonvulsants; D002606:Charcoal; D002220:Carbamazepine