Histological diagnosis of spinal chondrosarcoma by endobronchial ultrasound-guided transbronchial needle aspiration.
Rare neoplastic diseases including sarcomas can occur in the middle mediastinum. Obtaining a histological specimen is crucial for diagnosis and for establishing a treatment plan. Our research group has recently reported a minimal invasive method of tissue sampling of the mediastinum using direct real-time endobronchial ultrasound-guided transbronchial needle aspiration. By the use of this new modality, histological cores can be obtained for pathological diagnosis that can be used for immunohistochemistry as well as genetic analysis. A very rare case of spinal chondrosarcoma due to hereditary multiple exostoses successfully diagnosed by endobronchial ultrasound-guided transbronchial needle aspiration and by immunohistochemistry with genetic analysis is reported.
Nakajima
Takahiro
T
Department of Thoracic Surgery, Graduate School of Medicine, Chiba University, Chiba, Japan.
Yasufuku
Kazuhiro
K
Suzuki
Makoto
M
Sekine
Yasuo
Y
Shibuya
Kiyoshi
K
Hiroshima
Kenzo
K
Fujisawa
Takehiko
T
D001707:Biopsy, Needle / Q000379:methods; D001859:Bone Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D001999:Bronchoscopy; D002813:Chondrosarcoma / Q000000981:diagnostic imaging / Q000473:pathology*; D003937:Diagnosis, Differential; D019160:Endosonography; D006801:Humans; D008297:Male; D008875:Middle Aged; D013904:Thoracic Vertebrae