Smoothened gene mutations found in digestive cancer have no aberrant Hedgehog signaling activity.
Guleng
Bayasi
B
Tateishi
Keisuke
K
Ohta
Miki
M
Asaoka
Yoshinari
Y
Jazag
Amarsanaa
A
Lin
Lian-Jie
LJ
Tanaka
Yasuo
Y
Tada
Motohisa
M
Seto
Motoko
M
Kanai
Fumihiko
F
Kawabe
Takao
T
Omata
Masao
M
D015197:Carcinogenicity Tests; D003110:Colonic Neoplasms / Q000235:genetics*; D053823:Hedgehog Proteins / Q000235:genetics*; D006801:Humans; D000072079:Patched Receptors; D011956:Receptors, Cell Surface / Q000502:physiology*; D043562:Receptors, G-Protein-Coupled / Q000235:genetics*; D015398:Signal Transduction / Q000502:physiology*; D000072086:Smoothened Receptor; D014162:Transfection; D014407:Tumor Cells, Cultured
D053823:Hedgehog Proteins; D000072079:Patched Receptors; D011956:Receptors, Cell Surface; D043562:Receptors, G-Protein-Coupled; C491023:SMO protein, human; D000072086:Smoothened Receptor