title: A pilot study on the impact of body composition on bone and mineral metabolism in Parkinson's disease.
abstract: The impact of body composition on bone and mineral metabolism in Parkinson's disease (PD) was evaluated. Body fat mass, lean mass, bone mineral content, and bone mineral density (BMD) were measured by DXA in 22 PD patients and 104 controls. Female patients exhibited reduced body mass index, fat mass, and BMD compared to controls (p<0.05). Significant positive correlation was found between 25 OHD levels and BMC. Diminished bone mass in women with PD was found to be associated with alterations in body composition and low 25 OHD levels.
authors.affiliation: Department of Internal Medicine, Sección Osteopatías Médicas, Hospital de Clínicas, Universidad de Buenos Aires, Córdoba 2351, 8 piso, (1120) Buenos Aires, Argentina.
authors.forename: María C
authors.initials: MC
authors.lastname: Fernández
authors.forename: Muriel S
authors.initials: MS
authors.lastname: Parisi
authors.forename: Sergio P
authors.initials: SP
authors.lastname: Díaz
authors.forename: Silvina R
authors.initials: SR
authors.lastname: Mastaglia
authors.forename: Juan M
authors.initials: JM
authors.lastname: Deferrari
authors.forename: Mariana
authors.initials: M
authors.lastname: Seijo
authors.forename: Alicia
authors.initials: A
authors.lastname: Bagur
authors.forename: Federico
authors.initials: F
authors.lastname: Micheli
authors.forename: Beatriz
authors.initials: B
authors.lastname: Oliveri
mesh_terms: D015502:Absorptiometry, Photon; D000273:Adipose Tissue / Q000378:metabolism; D000368:Aged; D001823:Body Composition; D015992:Body Mass Index; D015519:Bone Density / Q000502:physiology; D001842:Bone and Bones / Q000378:metabolism*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010300:Parkinson Disease / Q000378:metabolism* / Q000473:pathology* / Q000503:physiopathology; D010865:Pilot Projects; D018709:Statistics, Nonparametric