title: Using fluence separation to account for energy spectra dependence in computing dosimetric a-Si EPID images for IMRT fields.
abstract: This study develops a method to improve the dosimetric accuracy of computed images for an amorphous silicon flat-panel imager. Radially dependent kernels derived from Monte Carlo simulations are convolved with the treatment-planning system's energy fluence. Multileaf collimator (MLC) beam hardening is accounted for by having separate kernels for open and blocked portions of MLC fields. Field-size-dependent output factors are used to account for the field-size dependence of scatter within the imager. Gamma analysis was used to evaluate open and sliding window test fields and intensity modulated patient fields. For each tested field, at least 99.6% of the points had gamma < 1 with a 3%, 3-mm criteria. With a 2%, 2-mm criteria, between 81% and 100% of points had gamma < 1. Patient intensity modulated test fields had 94%-100% of the points with gamma < 1 with a 2%, 2-mm criteria for all six fields tested. This study demonstrates that including the dependencies of kernel and fluence on radius and beam hardening in the convolution improves its accuracy compared with the use of radial and beam-hardening independent kernels; it also demonstrates that the resultant accuracy of the convolution method is sufficient for pretreatment, intensity modulated patient field verification.
authors.affiliation: Department of Radiation Oncology, Medical College of Virginia Hospitals, Virginia Commonwealth University, Richmond, Virginia 23298, USA. wli@vcu.edu
authors.forename: Weidong
authors.initials: W
authors.lastname: Li
authors.forename: Jeffrey V
authors.initials: JV
authors.lastname: Siebers
authors.forename: Joseph A
authors.initials: JA
authors.lastname: Moore
mesh_terms: D000465:Algorithms; D002138:Calibration; D004867:Equipment Design; D006801:Humans; D007091:Image Processing, Computer-Assisted; D015233:Models, Statistical; D009010:Monte Carlo Method; D010315:Particle Accelerators; D017785:Photons; D011874:Radiometry / Q000379:methods*; D011879:Radiotherapy Dosage; D011880:Radiotherapy Planning, Computer-Assisted; D050397:Radiotherapy, Intensity-Modulated / Q000379:methods*; D013053:Spectrophotometry / Q000379:methods*