Changes of aortae and pulmonary arteries under simulated microgravity and effects of NOS inhibitor on cardiovascular deconditioning.
The present study was to determine the effects of simulated microgravity (SM) on the pulmonary artery (PA) and aorta(TA), and to disclose the changes in pathophysiology of cardiovascular deconditioning(CVD) induced by SM and to explore the effects of NOS inhibitor (N-nitro-L-arginine methylester, L-NAME) on CVD. The high hemodynamics in pulmonary and systemic circulation of human bodies appeared during the initial period and super-regulatory phenomena under 6&#176;head-down tilt bed.
Wang
De-Sheng
DS
Institute of Space Medico- Engineering, Beijing 100094, China.
Liang
Wen-Bin
WB
Yuan
Ming
M
Li
Zhi-Li
ZL
Liu
Zhao-Xia
ZX
Yuan
Min
M
Guo
Yao-Yu
YY
Ma
Tie-Min
TM
Dong
Jian-Wen
JW