A meta-analysis on the effects of antibiotic treatment on duration of symptoms caused by infection with Campylobacter species.
Eleven randomized, controlled trials of antibiotic treatment versus placebo in patients with Campylobacter species infection were pooled in a meta-analysis. Antibiotic treatment shortened the duration of intestinal symptoms by 1.32 days (95% confidence interval, 0.64-1.99; P<.0001). Because of problems with drug resistance, a restrictive attitude towards the administration of antibiotics in uncomplicated cases is advised.
Ternhag
Anders
A
Karolinska Institutet, Department of Medical Epidemiology and Biostatistics, Stockholm, Sweden. anders.ternhag@karolinska.se
Asikainen
Tommi
T
Giesecke
Johan
J
Ekdahl
Karl
K
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D002169:Campylobacter Infections / Q000175:diagnosis / Q000188:drug therapy*; D002353:Carrier State; D002648:Child; D002675:Child, Preschool; D024881:Drug Resistance, Bacterial; D006801:Humans; D007223:Infant; D008875:Middle Aged; D016032:Randomized Controlled Trials as Topic
D000900:Anti-Bacterial Agents