Mikulicz syndrome, an uncommon entity in Pakistan.
A 38 years old woman presented with bilaterally symmetrical, painless swelling of the parotid, submandibular and sublingual glands. A fine needle aspiration biopsy revealed granulomatous histology with a few salivary ductal structures. On the basis of the histology, she was started on antituberculosis regimen until about 6 weeks later when she developed a skin rash on her shins, diagnosed as erythema nodosum co-existent with xerostomia. Her ESR was 38 mm and Mantoux test was negative. There was no lacrymal gland swelling and corneal tear film was normal on slit lamp examination. A diagnosis of sarcoidosis affecting the major salivary glands was made. The salivary glandular swelling, subsided within two weeks of treatment with oral prednisolone.
Mahmood
Khalid
K
Department of Dermatology, PAF Hospital, Masroor Airbase, Karachi. kmahmood@doctors.org.uk
Khan
Arif
A
Malik
Sikander Ali
SA
Ilyas
Muhammad
M
D000328:Adult; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D044963:Biopsy, Fine-Needle; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008882:Mikulicz' Disease / Q000175:diagnosis* / Q000473:pathology; D010154:Pakistan; D011239:Prednisolone / Q000627:therapeutic use; D012469:Salivary Glands / Q000473:pathology*; D012507:Sarcoidosis / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D014376:Tuberculosis / Q000175:diagnosis* / Q000473:pathology
D000893:Anti-Inflammatory Agents; D011239:Prednisolone