title: Cisplatin-induced hyperglycemic hyperosmolar coma.
abstract: We present a case of severe hyperglycaemic hyperosmolar derangement after treatment with cisplatin in a patient without previous diabetes mellitus. Limited data are available on this adverse reaction, explaining why impaired glucose handling due to cisplatin is not generally recognised.
authors.affiliation: Department of Internal Medicine, Medical Spectrum Twente Hospital, Enschede, the Netherlands. R.Komdeur@ziekenhuis-mst.nl
authors.forename: R
authors.initials: R
authors.lastname: Komdeur
authors.forename: J
authors.initials: J
authors.lastname: Derksen
authors.forename: M-C
authors.initials: MC
authors.lastname: Legdeur
authors.forename: B S
authors.initials: BS
authors.lastname: Hylkema
mesh_terms: D000328:Adult; D000970:Antineoplastic Agents / Q000009:adverse effects*; D002945:Cisplatin / Q000009:adverse effects*; D006801:Humans; D006944:Hyperglycemic Hyperosmolar Nonketotic Coma / Q000139:chemically induced* / Q000175:diagnosis; D008297:Male
chemical_list: D000970:Antineoplastic Agents; D002945:Cisplatin