Magnetic-fluorescent nanocomposites for biomedical multitasking.
Fluorescent magnetite nanocomposites based on magnetic nanoparticles, a polyhedral octaaminopropylsilsesquioxane and a porphyrin derivative have been prepared. The intracellular uptake of the nanocomposites by macrophage and bone osteoblast cells, and their potential as MRI contrast agents, has been demonstrated.
Corr
Serena A
SA
School of Chemistry. Trinity College Dublin, Dublin 2, Ireland.
O'Byrne
Aisling
A
Gun'ko
Yurii K
YK
Ghosh
Swapankumar
S
Brougham
Dermot F
DF
Mitchell
Siobhan
S
Volkov
Yuri
Y
Prina-Mello
Adriele
A
D000818:Animals; D003287:Contrast Media / Q000138:chemical synthesis* / Q000493:pharmacokinetics; D052203:Ferrosoferric Oxide; D005453:Fluorescence; D006801:Humans; D008264:Macrophages / Q000378:metabolism; D008279:Magnetic Resonance Imaging; D008280:Magnetics; D053761:Nanocomposites / Q000737:chemistry*; D053758:Nanoparticles; D010006:Osteoblasts / Q000378:metabolism
D003287:Contrast Media; D052203:Ferrosoferric Oxide