title: N-isopropylidene-N'-2-nitrobenzenesulfonyl hydrazine, a reagent for reduction of alcohols via the corresponding monoalkyl diazenes.
abstract: The reagent N-isopropylidene-N'-2-nitrobenzenesulfonyl hydrazine (IPNBSH) is used in the reduction of alcohols via the loss of dinitrogen from transiently formed monoalkyl diazene intermediates accessed by sequential Mitsunobu displacement, hydrolysis, and fragmentation under mild reaction conditions.
authors.affiliation: Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA 02139, USA. movassag@mit.edu
authors.forename: Mohammad
authors.initials: M
authors.lastname: Movassaghi
authors.forename: Omar K
authors.initials: OK
authors.lastname: Ahmad
mesh_terms: D000438:Alcohols / Q000737:chemistry*; D018360:Crystallography, X-Ray; D006834:Hydrazines / Q000737:chemistry*; D006868:Hydrolysis; D007202:Indicators and Reagents; D009682:Magnetic Resonance Spectroscopy; D009578:Nitrobenzenes / Q000737:chemistry*; D019163:Reducing Agents; D017550:Spectroscopy, Fourier Transform Infrared; D013237:Stereoisomerism
chemical_list: D000438:Alcohols; D006834:Hydrazines; D007202:Indicators and Reagents; D009578:Nitrobenzenes; D019163:Reducing Agents