Case of skin necrosis due to arginine monohydrochloride extravasation.
A 10-month-old child presented with an ulcerated lesion on his right arm. The lesion was caused by arginine monohydrochloride extravasation during growth hormone testing, performed 2 months before. On physical examination, there was a 3 cm x 4 cm oval sore, with a thick fibrous base and turgid, violaceous, raised edges on the dorsal aspect of the child's right hand and wrist. Conservative management with local medications led to complete resolution within 2 months.
Bassi
Elisa
E
Department of Human and Hereditary Pathology, Dermatology Clinic, IRCCS Policlinico San Matteo, Italy. elisa_bassi@yahoo.it
Lonati
Davide
D
Pandolfi
Roberta
R
Gatti
Marco
M
Jolliffe
Victoria M L
VM
Del Forno
Corrado
C
D001120:Arginine / Q000009:adverse effects*; D005119:Extravasation of Diagnostic and Therapeutic Materials / Q000150:complications* / Q000473:pathology; D006801:Humans; D007223:Infant; D008297:Male; D009336:Necrosis / Q000139:chemically induced; D012867:Skin / Q000473:pathology; D012883:Skin Ulcer / Q000139:chemically induced* / Q000473:pathology*; D014953:Wrist / Q000473:pathology
D001120:Arginine