Radiology of Gaucher disease (type 1) and bone manifestations: the Dutch experience.
Evaluating bone disease in Gaucher disease is a very important part of monitoring patients on therapy. In the Academic Medical Center (AMC) there is ample experience covering the evaluating of bone marrow involvement. Both state of the art Quantitative Chemical Shift Imaging (QCSI) as well as alternatives have been subject of research protocols. Our experiences are described.
Maas
M
M
Dept. of Radiology, Suite c1-210, Academic Medical Center, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands.
Hollak
C E M
CE
Akkerman
E M
EM
Aerts
J F M
JF
D001847:Bone Diseases / Q000188:drug therapy / Q000473:pathology*; D018450:Disease Progression; D016903:Drug Monitoring; D005776:Gaucher Disease / Q000188:drug therapy / Q000473:pathology*; D005962:Glucosylceramidase / Q000008:administration & dosage / Q000627:therapeutic use; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D009682:Magnetic Resonance Spectroscopy; D009426:Netherlands; D011994:Recombinant Proteins
D011994:Recombinant Proteins; D005962:Glucosylceramidase; C090568:imiglucerase