Effectiveness of early intervention in psychosis.
OBJECTIVE
Over 15 years, early intervention in psychosis has grown to become a mainstream funded approach to clinical care. This review examines recent developments in evaluating the effectiveness of early intervention. It considers identification and treatment of those at risk of psychosis, as well as interventions in the post-onset phase of illness.


RESULTS
Development of methods identifying those at risk of psychosis continues to evolve. Promising results in the prevention and delay of transition to psychotic disorder from a high-risk state have been found. Psychological and psychosocial interventions are important components of these preventive programmes. Two recent meta-analyses indicate that there is a consistent relationship between duration of untreated psychosis and outcome independent of other factors. Further evidence shows that early intervention reduces the duration of untreated psychosis, produces better outcomes in terms of symptomatic and functional domains, and is cheaper than standard models of care.


CONCLUSIONS
There is evidence that early intervention is effective for early psychosis. Some challenges remain. These include developing a greater focus on functional recovery and prevention of relapse.
Killackey
Eóin
E
Department of Psychology, University of Melbourne, Australia. eoin@unimelb.edu.au
Yung
Alison R
AR
D003131:Combined Modality Therapy; D042241:Early Diagnosis; D006801:Humans; D011379:Prognosis; D011618:Psychotic Disorders / Q000175:diagnosis / Q000534:rehabilitation*; D012307:Risk Factors; D012559:Schizophrenia / Q000175:diagnosis / Q000534:rehabilitation*; D016896:Treatment Outcome