Application of t1 and t2 maps for stereotactic deep-brain neurosurgery planning.
This work presents the application of a quantitative magnetic resonance imaging (MRI) technique in stereotactic deep-brain neurosurgery planning procedures. The high spatial resolution T<inf>1</inf>and T<inf>2</inf>maps acquired using this imaging method have been normalized to the standard CJH-27 brain coordinate system and integrated into a neurosurgical visualization and navigation system to improve the accuracy of surgical target localization. The T<inf>1</inf>and T<inf>2</inf>maps, along with the standardized anatomical and functional information within this system, can be navigated, non-rigidly registered, and arbitrarily processed. Once applied to individual patients, these maps facilitate the delineation of surgical targets. Our preliminary studies compared the centroids of segmented deep-brain nuclei based on the T<inf>1</inf>and T<inf>2</inf>maps with those according to Schaltenbrand and Wahren atlas, and with the actual surgical targets of 15 patients who had undergone thalamotomy, pallidotomy, and subthalamic nucleus deep-brain stimulation. The average displacement was 3.21mm&#177;0.80mm, indicating the potential capability of this system to accurately initiate target identifications.
Guo
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T
Robarts Research Institute, London, ON, Canada.
Peters
T
T
L Deoni
S
S
Parrent
A
A
Finnis
K
K