title: Postcataract endophthalmitis: incidence and microbial isolates in a United Kingdom region from 1996 through 2004.
abstract: OBJECTIVE
  To investigate the incidence of endophthalmitis after cataract surgery, analyze the microbiologic spectrum of infecting organisms, and assess the diagnostic utility of an anterior chamber paracentesis and vitreous biopsy.
  
  
  METHODS
  United Kingdom tertiary referral center used by 13 operating suites.
  
  
  METHODS
  A retrospective noncomparative consecutive series comprised 105 postcataract endophthalmitis cases.
  
  
  RESULTS
  The annual mean incidence of endophthalmitis over the study period was 0.099% (101/101 920) [corrected] and there was no significant increase in the incidence during the study. The culture-positive rate was 58.1% (61/105). Gram-positive microbes were isolated in 93.4% of cases (57/61), with coagulase-negative staphylococci accounting for 62.3% (38/61). Anterior chamber taps yielded positive cultures in 25.7% of cases, and vitreous biopsy was positive in 53.4%.
  
  
  CONCLUSIONS
  The incidence of endophthalmitis in this region of the United Kingdom remained stable, with gram-positive microbes accounting for 93.4% of the isolates. A combination of anterior chamber tap and vitreous biopsy should be performed in suspected cases of endophthalmitis.
authors.affiliation: Birmingham and Midland Eye Centre, City Hospital, Birmingham, United Kingdom. soozmollan@doctors.org.uk
authors.forename: Susan P
authors.initials: SP
authors.lastname: Mollan
authors.forename: Anna
authors.initials: A
authors.lastname: Gao
authors.forename: Alastair
authors.initials: A
authors.lastname: Lockwood
authors.forename: Omar M
authors.initials: OM
authors.lastname: Durrani
authors.forename: Lucilla
authors.initials: L
authors.lastname: Butler
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000867:Anterior Chamber / Q000382:microbiology; D001419:Bacteria / Q000302:isolation & purification; D015373:Bacterial Typing Techniques; D002387:Cataract Extraction; D009877:Endophthalmitis / Q000453:epidemiology* / Q000382:microbiology; D015818:Eye Infections, Bacterial / Q000453:epidemiology* / Q000382:microbiology; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D012189:Retrospective Studies; D006113:United Kingdom / Q000453:epidemiology; D014822:Vitreous Body / Q000382:microbiology