Ciprofloxacin-induced toxic optic neuropathy.
A case of bilateral toxic optic neuropathy that developed in the setting of prolonged oral ciprofloxacin use for the treatment of chronic osteomyelitis is described. The patient experienced progressive, bilateral and symmetrical visual loss, central scotomas and loss of colour vision over a 2-month period. The visual symptoms improved immediately upon cessation of ciprofloxacin with a gradual and near complete recovery over several years.
Samarakoon
Nadeeka
N
Harrisberg
Brian
B
Ell
Jonathan
J
D000284:Administration, Oral; D000890:Anti-Infective Agents / Q000009:adverse effects*; D002908:Chronic Disease; D002939:Ciprofloxacin / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009901:Optic Nerve Diseases / Q000139:chemically induced* / Q000503:physiopathology; D010019:Osteomyelitis / Q000188:drug therapy; D014786:Vision Disorders / Q000139:chemically induced / Q000503:physiopathology; D014792:Visual Acuity; D058609:Visual Field Tests; D014794:Visual Fields
D000890:Anti-Infective Agents; D002939:Ciprofloxacin