title: Electrocatalytic oxidation of guanine, guanosine, and guanosine monophosphate.
abstract: The electrochemical behavior of guanine, guanosine, and guanosine monophosphate (GMP) at redox polymer film modified indium tin oxide electrodes is examined by voltammetry and redox titration. Utilizing the redox polymer-coated electrodes as indicator electrodes, a new method for measuring the oxidation potentials, based on monitoring their catalytic oxidation by different redox polymer coated electrodes at different pH, was proposed in this work. The oxidation potentials of 0.81 V and 1.02 V versus normal hydrogen electrode were determined for guanine and guanosine/GMP under physiological conditions, the lowest oxidation potentials ever reported, to our knowledge.
authors.forename: Hong
authors.initials: H
authors.lastname: Xie
authors.forename: Daiwen
authors.initials: D
authors.lastname: Yang
authors.forename: Adam
authors.initials: A
authors.lastname: Heller
authors.forename: Zhiqiang
authors.initials: Z
authors.lastname: Gao
mesh_terms: D003198:Computer Simulation; D004563:Electrochemistry / Q000379:methods*; D006147:Guanine / Q000737:chemistry*; D006151:Guanosine / Q000737:chemistry*; D006157:Guanosine Monophosphate / Q000737:chemistry*; D006863:Hydrogen-Ion Concentration; D008956:Models, Chemical; D010084:Oxidation-Reduction; D010100:Oxygen / Q000737:chemistry*
chemical_list: D006151:Guanosine; D006147:Guanine; D006157:Guanosine Monophosphate; D010100:Oxygen