title: [Value of stem cell therapy for the treatment of stress incontinence. Current status and perspectives].
abstract: Parallel to a fundamental change in the therapeutic approach to managing stress incontinence, an increasing number of patients ask for reconstruction of the outer, striated urethral sphincter as therapy for urinary stress incontinence. Regenerative medicine is starting to offer solutions using stem cells as a part of oncological therapy or in reconstructive surgery. In addition to the many auspicious experimental approaches, one published study reports the effective therapeutic use of myogenic stem cells in urinary stress incontinent patients. Before this procedure is adopted into general clinical practice, further studies with validated evaluations and a sound legal basis are needed.
authors.affiliation: Klinik für Urologie, Universitätsklinikum, Hoppe-Seyler-Strasse 2, 72076, Tübingen, Deutschland. Karl.Sievert@med.uni-tuebingen.de
authors.forename: K-D
authors.initials: KD
authors.lastname: Sievert
authors.forename: B
authors.initials: B
authors.lastname: Amend
authors.forename: M
authors.initials: M
authors.lastname: Renninger
authors.forename: C
authors.initials: C
authors.lastname: Selent
authors.forename: G
authors.initials: G
authors.lastname: Feil
authors.forename: J
authors.initials: J
authors.lastname: Hennenlotter
authors.forename: T
authors.initials: T
authors.lastname: Skutella
authors.forename: R
authors.initials: R
authors.lastname: Möhle
authors.forename: H
authors.initials: H
authors.lastname: Northoff
authors.forename: A
authors.initials: A
authors.lastname: Stenzl
mesh_terms: D006801:Humans; D008297:Male; D010818:Practice Patterns, Physicians' / Q000639:trends*; D044968:Regenerative Medicine / Q000379:methods / Q000639:trends*; D033581:Stem Cell Transplantation / Q000379:methods* / Q000639:trends*; D014550:Urinary Incontinence, Stress / Q000601:surgery*; D013521:Urologic Surgical Procedures, Male / Q000379:methods* / Q000639:trends*