title: Comparison of transcriptional responses to osmotic stresses induced by NaCl and sorbitol additions in Saccharomyces cerevisiae using DNA microarray.
abstract: Transcriptional responses of laboratory and brewing strains of Saccharomyces cerevisiae to osmotic stresses induced by adding either NaCl or sorbitol to their cultures were compared by clustering DNA microarray data. Our results suggest that the difference in the transcriptional responses of the two strains between NaCl and sorbitol additions is small when the dynamics of the total change in gene expression are similar.
authors.affiliation: Department of Biotechnology, Graduate School of Engineering, Osaka University, 2-1 Yamadaoka, Suita, Osaka 565-0871, Japan.
authors.forename: Takashi
authors.initials: T
authors.lastname: Hirasawa
authors.forename: Kengo
authors.initials: K
authors.lastname: Ashitani
authors.forename: Katsunori
authors.initials: K
authors.lastname: Yoshikawa
authors.forename: Keisuke
authors.initials: K
authors.lastname: Nagahisa
authors.forename: Chikara
authors.initials: C
authors.lastname: Furusawa
authors.forename: Yoshio
authors.initials: Y
authors.lastname: Katakura
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Shimizu
authors.forename: Suteaki
authors.initials: S
authors.lastname: Shioya
mesh_terms: D004305:Dose-Response Relationship, Drug; D020869:Gene Expression Profiling; D015966:Gene Expression Regulation, Fungal / Q000187:drug effects / Q000502:physiology; D020411:Oligonucleotide Array Sequence Analysis; D009997:Osmotic Pressure / Q000187:drug effects; D020543:Proteome / Q000378:metabolism*; D012441:Saccharomyces cerevisiae / Q000187:drug effects / Q000378:metabolism*; D029701:Saccharomyces cerevisiae Proteins / Q000378:metabolism*; D012965:Sodium Chloride / Q000008:administration & dosage*; D013012:Sorbitol / Q000008:administration & dosage*; D014157:Transcription Factors / Q000378:metabolism*; D014158:Transcription, Genetic / Q000187:drug effects / Q000502:physiology*
chemical_list: D020543:Proteome; D029701:Saccharomyces cerevisiae Proteins; D014157:Transcription Factors; D012965:Sodium Chloride; D013012:Sorbitol