title: [Use of Tachosil in splenectomy in patients with clotting and blood composition disorders].
abstract: Splenectomy in patients suffering from onco-haematological conditions presents clotting-related problems which make correct haemostasis more difficult. Using operative haemostasis during splenectomy for onco-haematological conditions as a starting point, the authors report their personal clinical experience of the use of Tachosil, comparing it with other similar products and drawing some personal
  
  
  CONCLUSIONS
  To complete their reflexions on clotting problems during splenectomy in the course of onco-haematological diseases, the comparison with its use in oncological pathologies in other parenchymas, such as the kidney and liver, which also present operative haemostatic difficulties of a technical nature, is pointed out and the soundness of the results indicated. The cases of 3 patients suffering from severe clotting disturbances and treated with splenectomy and 1 patient suffering from clear cell renal carcinoma and subjected to nephrectomy in which Tachosil was used as an aid to haemostasis are reported. In the light of these cases, it can be stated that, albeit with the persistence of difficulties related to the changed clotting capacities resulting from the basic disease, the use of Tachosil has proved effective as an aid in haemostasis and suggests the validity of its use in elective and emergency splenectomy, in these types of patient.
authors.affiliation: Divisione di Chirurgia Generale, Scuola di Specializzazione in Chirurgia Generale in Urgenza, Università degli Studi di Pavia, Polo Universitario Città di Pavia, Pavia, Italy. tglfba@tele2.it
authors.forename: F
authors.initials: F
authors.lastname: Tagliabue
authors.forename: C
authors.initials: C
authors.lastname: D'Angelo
authors.forename: W
authors.initials: W
authors.lastname: Zuccon
authors.forename: C
authors.initials: C
authors.lastname: Giorgetta
authors.forename: F
authors.initials: F
authors.lastname: Gambarini
authors.forename: L
authors.initials: L
authors.lastname: Bonandrini
mesh_terms: D000328:Adult; D000368:Aged; D001778:Blood Coagulation Disorders / Q000150:complications; D004338:Drug Combinations; D005260:Female; D005340:Fibrinogen; D006801:Humans; D008297:Male; D008875:Middle Aged; D019106:Postoperative Hemorrhage / Q000209:etiology / Q000517:prevention & control*; D013156:Splenectomy / Q000009:adverse effects*; D015503:Surgical Sponges; D013917:Thrombin
chemical_list: D004338:Drug Combinations; C518955:TachoSil; D005340:Fibrinogen; D013917:Thrombin