The raphe magnus/pallidus regulates sweat secretion and skin vasodilation of the cat forepaw pad: a preliminary electrical stimulation study.
In the human palm/sole, mental or physical stimuli induce an increase in sweat secretion and a decrease in skin blood flow (SkBF). However, the central pathways of these responses remain unclear. We measured sweat secretion and SkBF in the cat footpad by electrically stimulating the raphe. Stimulation of the rostral raphe magnus/pallidus elicited a reduction in SkBF without affecting sweat secretion. Stimulation of the mid to caudal raphe magnus/pallidus elicited an increase in both sweat secretion and SkBF. The raphe magnus/pallidus may play a crucial role in skin vasomotor and sudomotor responses in the cat footpad.
Asahina
Masato
M
Department of Neurology, Chiba University School of Medicine, 1-8-1 Inohana, Chuo-ku, Chiba 260-8670, Japan. asahina@faculty.chiba-u.jp
Sakakibara
Ryuji
R
Liu
Zhi
Z
Ito
Takashi
T
Yamanaka
Yoshitaka
Y
Nakazawa
Ken
K
Shimizu
Eiji
E
Hattori
Takamichi
T
D000818:Animals; D017776:Autonomic Pathways / Q000502:physiology; D001833:Body Temperature Regulation / Q000502:physiology; D002415:Cats; D004525:Efferent Pathways / Q000502:physiology; D004558:Electric Stimulation; D005552:Forelimb / Q000098:blood supply / Q000294:innervation*; D008297:Male; D008526:Medulla Oblongata / Q000033:anatomy & histology / Q000502:physiology; D008833:Microcirculation / Q000294:innervation* / Q000502:physiology; D011903:Raphe Nuclei / Q000033:anatomy & histology / Q000502:physiology*; D012039:Regional Blood Flow / Q000502:physiology; D012867:Skin / Q000098:blood supply / Q000294:innervation*; D013545:Sweat Glands / Q000294:innervation* / Q000378:metabolism; D013546:Sweating / Q000502:physiology; D014664:Vasodilation / Q000502:physiology*; D014666:Vasomotor System / Q000502:physiology