A de novo centric fission of chromosome 11 in a patient with recurrent miscarriages.
We report on a de novo centric fission of chromosome 11 in a healthy female referred for chromosome analysis due to recurrent miscarriages. Both fission products were mitotically stable. This centric fission of chromosome 11 appears to have no clinical significance for this patient other than recurrent miscarriages.
Shim
Sung Han
SH
Department of Medical Genetics, College of Medicine, Hanyang University, Seoul, Korea.
Lee
Cheol-Hoon
CH
Lee
Ji-Yeon
JY
Shin
Eun-Sim
ES
Kyhm
Jee Hong
JH
Park
Moon-Il
MI
Chung
Sung-Ro
SR
Cho
Youl-Hee
YH
D000026:Abortion, Habitual / Q000235:genetics*; D000328:Adult; D002869:Chromosome Aberrations; D002880:Chromosomes, Human, Pair 11; D005260:Female; D006801:Humans