title: Childhood adversity, recent life events and depression in late life.
abstract: BACKGROUND
  The study investigates whether persons who have experienced childhood adversity are more likely to develop depressive symptoms when faced with recent events.
  
  
  METHODS
  Data were used from a population-based sample, aged 55 to 85 years (n=1887), which were not depressed at baseline. Childhood adversities and recent stressful life events were retrospectively assessed. Depressive symptoms were measured with the CES-D.
  
  
  RESULTS
  14.4% of our sample experienced adverse events during childhood (<18 yrs) and 35.4% experienced recent events. Associations of depressive symptoms were found with both, childhood adversity (OR 1.80, 95% CI 1.21-2.69) and recent life events (OR 1.42, 95% CI 1.01-2.00). The effect of recent events on depressive symptoms was not modified by childhood adversity.
  
  
  CONCLUSIONS
  Underreporting may be present due to unwillingness to report embarrassing events or to disclose painful memories.
  
  
  CONCLUSIONS
  No evidence was found for the assumption that older persons were more vulnerable for depression in reaction to recent life events when they were exposed to childhood adversity.
authors.affiliation: Department of Psychiatry, EMGO Institute, VU University Medical Center, Amsterdam, The Netherlands. h.comijs@vumc.nl
authors.forename: Hannie C
authors.initials: HC
authors.lastname: Comijs
authors.forename: Aartjan T F
authors.initials: AT
authors.lastname: Beekman
authors.forename: Filip
authors.initials: F
authors.lastname: Smit
authors.forename: Marijke
authors.initials: M
authors.lastname: Bremmer
authors.forename: Theo
authors.initials: T
authors.lastname: van Tilburg
authors.forename: Dorly J H
authors.initials: DJ
authors.lastname: Deeg
mesh_terms: D000293:Adolescent; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D003866:Depressive Disorder / Q000175:diagnosis / Q000523:psychology*; D005260:Female; D006801:Humans; D008016:Life Change Events; D008297:Male; D008875:Middle Aged; D009426:Netherlands; D012307:Risk Factors