title: Use of intraluminal protection in colonic anastomosis in dogs.
abstract: OBJECTIVE
  To test the use of intraluminal protection in colonic anastomosis without intestinal cleansing. The intraluminal liner was fashioned from porcine submucosa preserved in glycerin and then fixed 10 cm anteriorly to the anastomotic site. This technique was compared with the one used in termino-terminal colonic anastomosis without intraluminal protection.
  
  
  METHODS
  Twenty-eight dogs were divided into two groups of fourteen animals each. Clinical and histopathological tests were performed on the fourth and twenty-first postoperative days.
  
  
  RESULTS
  The morbidity and mortality rates were higher in animals that did not receive the intraluminal liner. Histopathological examinations in animals in which the intraluminal liner was used showed better healing, characterized by milder inflammation and increased amount of collagen.
  
  
  CONCLUSIONS
  It can be concluded that the use of intraluminal protection decreases complication rates in colonic anastomosis and promotes better healing.
authors.affiliation: Laboratory of Experimental Surgery, Department of Surgery, Federal University of Rio de Janeiro, 28010-400 Campus dos Goytacazes, RJ, Brazil. andrevet@uenf.br
authors.forename: André Lacerda de Abreu
authors.initials: AL
authors.lastname: Oliveira
authors.forename: Nelson
authors.initials: N
authors.lastname: Jamel
authors.forename: Domingos Penna
authors.initials: DP
authors.lastname: Lacombe
authors.forename: Manuel Domingos
authors.initials: MD
authors.lastname: Gonçalves
authors.forename: Edmundo Jorge
authors.initials: EJ
authors.lastname: Abílio
authors.forename: José Eduardo Ferreira
authors.initials: JE
authors.lastname: Manso
authors.forename: Alessandra Castello da
authors.initials: AC
authors.lastname: Costa
mesh_terms: D000714:Anastomosis, Surgical / Q000009:adverse effects / Q000379:methods / Q000401:mortality; D000818:Animals; D003094:Collagen; D003106:Colon / Q000601:surgery*; D004285:Dogs; D005260:Female; D005990:Glycerol / Q000627:therapeutic use*; D007249:Inflammation; D007413:Intestinal Mucosa / Q000637:transplantation*; D023421:Models, Animal; D013529:Surgical Wound Dehiscence / Q000209:etiology; D013552:Swine; D014945:Wound Healing
chemical_list: D003094:Collagen; D005990:Glycerol