How do I fatten thee? Let me count the ways...
Glycerol-3-phosphate acyltransferase (GPAT) initiates the synthesis of triacylglycerol and phospholipids and, in the process, regulates the formation of several lipid metabolites known to be intracellular signaling molecules. The recent identification of a new GPAT isoform (Cao et al., 2006) suggests a role for GPAT isoforms in nutrient-mediated signaling.
Coleman
Rosalind A
RA
Department of Nutrition and Pediatrics, University of North Carolina, CB#7461, Chapel Hill, NC 27599, USA. rcoleman@unc.edu
D000818:Animals; D005992:Glycerol-3-Phosphate O-Acyltransferase / Q000172:deficiency / Q000378:metabolism*; D006801:Humans; D007527:Isoenzymes / Q000172:deficiency / Q000378:metabolism; D050356:Lipid Metabolism; D008099:Liver / Q000201:enzymology; D051379:Mice; D008928:Mitochondria / Q000201:enzymology; D010743:Phospholipids / Q000096:biosynthesis; D014280:Triglycerides / Q000096:biosynthesis
D007527:Isoenzymes; D010743:Phospholipids; D014280:Triglycerides; D005992:Glycerol-3-Phosphate O-Acyltransferase