title: The phase-variable allele of the pilus glycosylation gene pglA is not strongly associated with strains of Neisseria gonorrhoeae isolated from patients with disseminated gonococcal infection.
abstract: The Neisseria gonorrhoeae pglA gene has two alleles, one of which is phase variable. A previous study reported that all disseminated gonococcal infection (DGI) isolates contained the phase-variable allele and proposed a causal link. In the present study of 81 strains no absolute correlation between DGI and the phase-variable pglA allele was observed.
authors.affiliation: School of Molecular and Microbial Sciences, The University of Queensland, Brisbane, QLD 4072, Australia.
authors.forename: P M
authors.initials: PM
authors.lastname: Power
authors.forename: S C
authors.initials: SC
authors.lastname: Ku
authors.forename: K
authors.initials: K
authors.lastname: Rutter
authors.forename: M J
authors.initials: MJ
authors.lastname: Warren
authors.forename: E A
authors.initials: EA
authors.lastname: Limnios
authors.forename: J W
authors.initials: JW
authors.lastname: Tapsall
authors.forename: M P
authors.initials: MP
authors.lastname: Jennings
mesh_terms: D000483:Alleles; D023181:Antimicrobial Cationic Peptides / Q000235:genetics*; D010861:Fimbriae, Bacterial / Q000378:metabolism*; D005798:Genes, Bacterial / Q000502:physiology; D006031:Glycosylation; D006069:Gonorrhea / Q000382:microbiology* / Q000635:transmission; D006801:Humans; D009344:Neisseria gonorrhoeae / Q000235:genetics* / Q000378:metabolism
chemical_list: D023181:Antimicrobial Cationic Peptides; C045866:peptide-Gly-Leu-amide