title: Using the forced oscillation technique to evaluate respiratory resistance in individuals with silicosis.
abstract: OBJECTIVE
  To evaluate the resistance values obtained through the use of the forced oscillation technique in patients with varying degrees of airway obstruction resulting from silicosis.
  
  
  METHODS
  A total of 40 never-smoking volunteers were analyzed: 10 were healthy subjects with no history of pulmonary disease or silica exposure, and 30 had silicosis. The forced oscillation technique was used to examine the subjects, and spirometry was used as a reference in order to classify the obstruction by degree. This classification resulted in five groups: control (n = 10); normal exam, composed of individuals diagnosed clinically and radiologically with silicosis but presenting normal spirometry results (n = 7); mild obstruction (n = 10); moderate obstruction (n = 8); and severe obstruction (n = 5).
  
  
  RESULTS
  The reduction observed in the spirometric values corresponded to a significant increase in the total respiratory resistance (p < 0.001), as well as in airway resistance (p < 0.003). A significant reduction in ventilation homogeneity was also observed (p < 0.004).
  
  
  CONCLUSIONS
  In individuals with silicosis, the additional respiratory resistance-related data obtained through the use of the forced oscillation technique can complement spirometric data. Therefore, the forced oscillation technique presents great potential for the analysis of such patients.
authors.affiliation: Laboratory of Biomedical Instrumentation, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, Rio de Janeiro, Brazil.
authors.forename: Jayme Alves
authors.initials: JA
authors.lastname: de Mesquita Júnior
authors.forename: Agnaldo José
authors.initials: AJ
authors.lastname: Lopes
authors.forename: José Manoel
authors.initials: JM
authors.lastname: Jansen
authors.forename: Pedro Lopes
authors.initials: PL
authors.lastname: de Melo
mesh_terms: D000328:Adult; D000402:Airway Obstruction / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology*; D000403:Airway Resistance / Q000502:physiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009991:Oscillometry / Q000379:methods*; D012016:Reference Values; D015203:Reproducibility of Results; D012129:Respiratory Function Tests / Q000379:methods*; D012720:Severity of Illness Index; D012829:Silicosis / Q000150:complications / Q000503:physiopathology*