[The impact of cigarette smoking on oocytes and embryos quality during in vitro fertilization program].
The aim of the study was to investigate the influence of smoking on different parameters in woman treated by in vitro fertilization. Twenty-seven patients undergoing IVF were classified as smokers and 32 as non-smokers on the basis of medical history. Smokers had decreased number of retrieved oocytes compared with non-smokers (p < 0.05). Our study demonstrates that active cigarette smoking increases the zona pellucida thickness of oocytes and decreases a quality of oocytes. Cigarette smoking is associated with reduced number of embryo obtaining after classical in vitro fertilization in smokers compared to non-smokers, There was no significant difference in number embryos obtained after ICSI treatment in both groups. Women who smoked had also statistically significantly lower quality of embryos versus non-smokers patients. The clinical pregnancy rate per cycle in smokers was significantly lower.
Depa-Martynów
Magdalena
M
Klinika Niepłodności i Endokrynologii Rozrodu, Katedra Ginekologii i Połoznictwa, Akademia Medyczna w Poznaniu.
Jedrzejczak
Piotr
P
Taszarek-Hauke
Grazyna
G
Jósiak
Magdalena
M
Pawelczyk
Leszek
L
D000328:Adult; D016022:Case-Control Studies; D004622:Embryo, Mammalian / Q000473:pathology / Q000648:ultrastructure*; D004784:Environmental Monitoring; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D007247:Infertility, Female / Q000473:pathology* / Q000628:therapy*; D009865:Oocytes / Q000473:pathology / Q000648:ultrastructure*; D011247:Pregnancy; D012907:Smoking / Q000473:pathology*; D020554:Sperm Injections, Intracytoplasmic; D016896:Treatment Outcome; D015044:Zona Pellucida / Q000473:pathology / Q000648:ultrastructure*