title: Electro-mechanical imaging of the heart using tagged MRI and ECG/MCG arrays.
abstract: We develop a computational framework for estimating simultaneously mechanical properties (active stress, passive elasticities, and mechanical activation time) and electrical properties (current density and electrical activation time.) First, we present a method for estimating the mechanical properties, active stress and passive elasticity modulus, of the in vivo heart using magnetic resonance imaging (MRI) tissue-tagging and intra-ventricular pressure measurements. Next, we present an algorithm for estimating the current density of the heart using electrocardiography (ECG) and magnetocardiography (MCG) sensor arrays. Finally, we present an inverse electro-mechanical model based on the excitation-contraction coupling and dynamic analysis which includes inertial forces and moving mesh. The proposed model has significant potential for studying the coupling effects in the whole heart.
authors.affiliation: Dept. of Electr. & Comput. Eng., Illinois Univ., Urbana, IL, USA.
authors.forename: Aleksandar
authors.initials: A
authors.lastname: Jeremic
authors.forename: Arye
authors.initials: A
authors.lastname: Nehorai