title: Alagille syndrome: prenatal sonographic findings.
abstract: We report a case of Alagille syndrome in which sonographic examination revealed the presence of angulation of the fetal spine due to vertebral fusion as well as tetralogy of Fallot. Histologic examination after pregnancy termination revealed the presence of agenesis of the gallbladder with a paucity of intrahepatic bile ducts, leading to the diagnosis of Alagille syndrome. In the presence of cardiac and axial skeletal anomalies, attention should be paid to the fetal gallbladder, whose absence would signal a diagnosis of Alagille syndrome.
authors.affiliation: Perinatal Diagnostic Center, Inova Alexandria 4302 Seminary Road, Alexandria, VA 22314, USA.
authors.forename: Ghidini
authors.initials: G
authors.lastname: Alessandro
authors.forename: Maddalena
authors.initials: M
authors.lastname: Incerti
authors.forename: Marianna
authors.initials: M
authors.lastname: Andreani
mesh_terms: D000028:Abortion, Induced; D000328:Adult; D016738:Alagille Syndrome / Q000000981:diagnostic imaging* / Q000473:pathology*; D000650:Amnion; D005260:Female; D006801:Humans; D007267:Injections; D008297:Male; D011247:Pregnancy; D011859:Radiography; D050497:Stillbirth; D016216:Ultrasonography, Prenatal