title: Magnetic-fluorescent nanocomposites for biomedical multitasking.
abstract: Fluorescent magnetite nanocomposites based on magnetic nanoparticles, a polyhedral octaaminopropylsilsesquioxane and a porphyrin derivative have been prepared. The intracellular uptake of the nanocomposites by macrophage and bone osteoblast cells, and their potential as MRI contrast agents, has been demonstrated.
authors.affiliation: School of Chemistry. Trinity College Dublin, Dublin 2, Ireland.
authors.forename: Serena A
authors.initials: SA
authors.lastname: Corr
authors.forename: Aisling
authors.initials: A
authors.lastname: O'Byrne
authors.forename: Yurii K
authors.initials: YK
authors.lastname: Gun'ko
authors.forename: Swapankumar
authors.initials: S
authors.lastname: Ghosh
authors.forename: Dermot F
authors.initials: DF
authors.lastname: Brougham
authors.forename: Siobhan
authors.initials: S
authors.lastname: Mitchell
authors.forename: Yuri
authors.initials: Y
authors.lastname: Volkov
authors.forename: Adriele
authors.initials: A
authors.lastname: Prina-Mello
mesh_terms: D000818:Animals; D003287:Contrast Media / Q000138:chemical synthesis* / Q000493:pharmacokinetics; D052203:Ferrosoferric Oxide; D005453:Fluorescence; D006801:Humans; D008264:Macrophages / Q000378:metabolism; D008279:Magnetic Resonance Imaging; D008280:Magnetics; D053761:Nanocomposites / Q000737:chemistry*; D053758:Nanoparticles; D010006:Osteoblasts / Q000378:metabolism
chemical_list: D003287:Contrast Media; D052203:Ferrosoferric Oxide