title: Nebulised DNase in the treatment of life threatening asthma.
abstract: A 25-year-old pregnant patient developed life-threatening asthma refractory to all standard treatment including anaesthetic agents. Ventilatory pressures continued to rise with impending cardio-respiratory arrest. The introduction of nebulised endotracheal DNase however resulted in a rapid and dramatic improvement with good clinical outcome.
authors.affiliation: Frimley Park Hospital NHS Foundation Trust, Camberley, Surrey, United Kingdom. jiminio@doctors.org.uk
authors.forename: James H K
authors.initials: JH
authors.lastname: Hull
authors.forename: Nick
authors.initials: N
authors.lastname: Castle
authors.forename: Ronald K
authors.initials: RK
authors.lastname: Knight
authors.forename: Timothy B L
authors.initials: TB
authors.lastname: Ho
mesh_terms: D000328:Adult; D001249:Asthma / Q000188:drug therapy*; D003851:Deoxyribonucleases / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D009330:Nebulizers and Vaporizers; D011247:Pregnancy; D016896:Treatment Outcome
chemical_list: D003851:Deoxyribonucleases