title: A novel HLA-A2 variant, A*9203, identified by sequence-based typing.
abstract: HLA-A*9203, found in Taiwan using sequence-based typing method, was identical to HLA-A*0207 in exon 3 but differed in exon 2 by five nucleotide substitutions at positions 240-282 corresponding to three amino acid changes at codons 62, 66 and 70. Since this substitution motif is also seen in A*11 and A*03, it is likely that a gene conversion event from A*11 or A*03 to a A*0207 backbone may have been the process used in generating HLA-A*9203.
authors.affiliation: Transfusion Medicine Laboratory, Medical Research Department, Mackay Memorial Hospital, Taipei, Taiwan.
authors.forename: C-C
authors.initials: CC
authors.lastname: Chu
authors.forename: H-L
authors.initials: HL
authors.lastname: Lee
authors.forename: M
authors.initials: M
authors.lastname: Lin
mesh_terms: D000595:Amino Acid Sequence; D019943:Amino Acid Substitution; D044466:Asian People / Q000235:genetics; D001483:Base Sequence; D015234:HLA-A Antigens / Q000235:genetics*; D015789:HLA-A2 Antigen / Q000235:genetics*; D006801:Humans; D008969:Molecular Sequence Data; D017422:Sequence Analysis, DNA; D013624:Taiwan
chemical_list: D015234:HLA-A Antigens; C519204:HLA-A*02:103 antigen; D015789:HLA-A2 Antigen