The Biological Effect of the NanoTiO<inf>2</inf>and Its Toxicity.
The proliferation behavior of the person's liver cell under actions of the nanoTiO<inf>2</inf>has been looked into by 3-(4,5-dimethylthiazol 2-yl)-2,5 diphenyltetrazolium bromide (MTT) colorimetric method of Mosmann. In this case we first give some elementary properties of the nanoTiO<inf>2</inf>and do further the liver cell cultures, and add the nano TiO<inf>2</inf>into the cells. In accordance with biological rules we measure the proliferation state of the liver cell in normal condition. The result obtained show that the influence of the nanoTiO<inf>2</inf>on the proliferation of the person's liver cell is very small, when compared with that of the control group. We found further out the size of the toxicity of the nanoTiO<inf>2</inf>to the chick embryo fibroblast (CEF) cells by the MTT colorimetric method. Thus we determine the toxicity for the TiO<inf>2</inf>s of 100nm and of 1000nm by the toxicology which are all first score (or degree).
Xiao-Feng
Pang
P
Institute of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu 610054), Sichuan, P.R.China.
Lewei
Liu
L
Zhi Hong
Liu
L
Qiang
Zhao
Z