A causal discovery approach to identifying active components of herbal medicine.
In the present study, a stepwise causal adjacent relationship discovery (STEPCARD) method has been developed to identify active components of herbal medicine. The combination of two active components had been successfully recognized from a typical Chinese formulation. Animal experiments validated the computational result. It indicates current work might be helpful to accelerate the process of new drug discovery from herbal medicine.
Wang
Yi
Y
College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310027, China.
Wang
Xuewei
X
Cheng
Yiyu
Y