Reagent-dependent regioselective control in multiple carbohydrate esterifications.
Regioselective control in organotin-mediated multiple acylation of carbohydrates is presented. The acylation reagent could be efficiently used to direct the product formation. Reagent-dependent thermodynamic and kinetic control and dynamic assistance mechanisms are suggested, resulting in the efficient preparation of building blocks that normally require many steps with traditional synthesis.
Dong
Hai
H
KTH-Royal Institute of Technology, Department of Chemistry, Teknikringen 30, S-10044 Stockholm, Sweden.
Pei
Zhichao
Z
Byström
Styrbjörn
S
Ramström
Olof
O