title: Congenital shortening of the flexor digitorum profundus muscle.
abstract: An 8-year-old boy with a history of the inability to extend the middle finger at the proximal interphalangeal and distal interphalangeal joints with the wrist and metacarpophalangeal joints in the neutral position since the age of 5 months had surgery. The flexor digitorum profundus muscle of the middle finger had a short muscle belly and was replaced in part with mature fat tissue. Histologic examination of the resected tissue showed replacement of a part of the muscle with mature fat tissue. It was speculated that some myosatellite cells, which typically differentiate into skeletal muscle cells, may have erroneously differentiated into adipocytes in the first postnatal year, during which complete development of skeletal muscles occurs.
authors.affiliation: Department of Orthopaedic Surgery, National Center for Child Health and Development, Tokyo, Japan. ttkg@2000.jukuin.keio.ac.jp
authors.forename: Takehiko
authors.initials: T
authors.lastname: Takagi
authors.forename: Shinichiro
authors.initials: S
authors.lastname: Takayama
authors.forename: Hiroyasu
authors.initials: H
authors.lastname: Ikegami
authors.forename: Toshiyasu
authors.initials: T
authors.lastname: Nakamura
mesh_terms: D002648:Child; D003286:Contracture / Q000151:congenital / Q000601:surgery; D005385:Fingers / Q000601:surgery*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D018482:Muscle, Skeletal / Q000002:abnormalities* / Q000473:pathology / Q000601:surgery; D013710:Tendons / Q000002:abnormalities / Q000601:surgery