Patterns of venous reflux and obstruction in patients with skin damage due to chronic venous disease.
Identified were characteristics of individuals with skin damage related to chronic venous disease. Patients with chronic venous disease (n = 164) were evaluated with duplex ultrasound imaging and were placed in classes 4, 5, and 6 according to the CEAP classification. Their findings were compared with 100 class 2 controls. The prevalence of deep venous thrombosis was higher in the study group (23.7%) versus controls (5.1%; P < .0001), as was the prevalence of deep, perforator, and combined patterns of disease (P < .0001, P < .0007, and P < .0001). The mean duration of disease in controls 2 was shorter compared with the study group (P = .0019). The prevalence of reflux and obstruction within the study group was higher than in controls (P = .0021). Skin changes accurately reflect severity of chronic venous disease. Superficial and perforator vein reflux is the major cause of disease.
Labropoulos
Nicos
N
Department of Surgery, Loyola University Medical Center, Maywood, IL, USA. nlabrop@yahoo.com
Patel
Parag J
PJ
Tiongson
Jay E
JE
Pryor
Landon
L
Leon
Luis R
LR
Tassiopoulos
Apostolos K
AK
D000328:Adult; D002908:Chronic Disease; D005260:Female; D006801:Humans; D007087:Illinois / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D011446:Prospective Studies; D012042:Registries; D012720:Severity of Illness Index; D012867:Skin / Q000473:pathology*; D013997:Time Factors; D018616:Ultrasonography, Doppler, Duplex; D014647:Varicose Ulcer / Q000453:epidemiology / Q000209:etiology* / Q000473:pathology; D014648:Varicose Veins / Q000150:complications* / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000503:physiopathology; D014689:Venous Insufficiency / Q000150:complications* / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000503:physiopathology; D020246:Venous Thrombosis / Q000150:complications* / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000503:physiopathology