title: [Higher incidence of type 1 diabetes in males--a study in teenagers and young adults in Krakow region in 1987-1999].
abstract: Numerous reports of increasing incidence of type 1 diabetes worldwide, and similar tendency in children population in Poland prompted the study aiming at evaluating the incidence of type 1 diabetes in a population aged 15-29 years in Krakow area (voivodeship) in 1987-1999. The type 1 diabetes registry established in Chair and Department of Endocrinology CMUJ in 1986 was continued. To improve ascertainment two independent data sources were used: hospital departments and outpatient diabetic clinics. Definite inclusion criteria were assigned and data verified. Incidence rates and trends of incidence were calculated for gender and age groups, differences between the groups were analyzed. Incidence rates were standardized for the European population. The seasonality of disease occurrence was calculated. Registry ascertainment was assessed using "capture-recapture" method. Incidence of type 1 diabetes showed a significant increase in the whole group (0.32 new cases/100,000/year), mainly due to marked incidence increase observed in males (0.53). The oldest age group (25-29 years) showed the most rapid increase in diabetes type 1 incidence (1.07). Seasonality of disease occurrence was found in females. Mean ascertainment was 81%, with the lowest values in 1996-1999. The results obtained indicate that the increase of type 1 diabetes incidence in the age group 15-29 years in Krakow region was due to rapidly increasing incidence in males, especially those aged 25-29 years. Lack of disease occurrence seasonality in this group may indicate a role of other factors (associated with lifestyle or hormonal) responsible for such marked increase in young males, not seen in females. The study was terminated in 1999 due to new administrative division of the country and problems with data collection from the area of non-longer existing Krakow voivodeship.
authors.affiliation: Katedra i Klinika Endokrynologii, CM UJ, Krakowie. empj@cm-uj.krakow.pl
authors.forename: Ewa
authors.initials: E
authors.lastname: Płaczkiewicz-Jankowska
authors.forename: Magdalena
authors.initials: M
authors.lastname: Szurkowska
authors.forename: Agnieszka
authors.initials: A
authors.lastname: Kiełtyka
authors.forename: Zbigniew
authors.initials: Z
authors.lastname: Szybinski
authors.forename: Bohdan
authors.initials: B
authors.lastname: Huszno
mesh_terms: D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000367:Age Factors; D003922:Diabetes Mellitus, Type 1 / Q000453:epidemiology*; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D011044:Poland / Q000453:epidemiology; D044382:Population Groups; D015995:Prevalence; D012042:Registries; D012189:Retrospective Studies; D012621:Seasons; D017678:Sex Distribution; D012737:Sex Factors