title: Traumatic ulcerative granuloma with stromal eosinophilia of the oral mucosa: histological and immunohistochemical analysis of three cases.
abstract: Traumatic ulcerative granuloma with stromal eosinophilia is an ulcerated oral lesion which pathogenesis is still unclear. Clinically, this disease is characterized by the presence of chronic ulcerative lesions with elevated and indurated borders in the oral mucosa. It usually develops rapidly and persists for several weeks or months, it presents mainly on the tongue but other areas such as gingival, cheek and vestibular mucosa may also be involved. We report three cases showing their clinical, histological and immunohistochemical analysis. In this study the authors underline the importance of a correct differential diagnosis and monitoring of these patients in order to prevent the development of possible serious complications.
authors.affiliation: Department of Odontostomatology and Surgery, University of Bari, Bari, Italy. giovannipilolli@yahoo.it
authors.forename: G P
authors.initials: GP
authors.lastname: Pilolli
authors.forename: A
authors.initials: A
authors.lastname: Lucchese
authors.forename: M
authors.initials: M
authors.lastname: Scivetti
authors.forename: E
authors.initials: E
authors.lastname: Maiorano
authors.forename: G
authors.initials: G
authors.lastname: Favia
mesh_terms: D000293:Adolescent; D000328:Adult; D017252:CD3 Complex / Q000032:analysis; D018956:CD5 Antigens / Q000032:analysis; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis; D002648:Child; D003937:Diagnosis, Differential; D004803:Eosinophilic Granuloma / Q000145:classification / Q000175:diagnosis / Q000276:immunology / Q000473:pathology*; D005260:Female; D006801:Humans; D017730:Ki-1 Antigen / Q000032:analysis; D008232:Lymphoproliferative Disorders / Q000145:classification / Q000276:immunology / Q000473:pathology*; D008297:Male; D019226:Oral Ulcer / Q000145:classification / Q000175:diagnosis / Q000276:immunology / Q000473:pathology*; D012075:Remission, Spontaneous; D017154:Stromal Cells / Q000473:pathology; D016176:T-Lymphocyte Subsets / Q000737:chemistry / Q000473:pathology; D014060:Tongue Diseases / Q000175:diagnosis / Q000276:immunology / Q000473:pathology*; D014062:Tongue Neoplasms / Q000175:diagnosis
chemical_list: D017252:CD3 Complex; D018956:CD5 Antigens; D017730:Ki-1 Antigen