title: [Genetic polymorphisms of 14 Y-chromosomal short tandem repeat loci and haplotypes in Tibetan].
abstract: OBJECTIVE
  To reveal the allelic frequencies and haplotype frequencies of fourteen Y-chromosome short tandem repeat (STR) loci in a Tibetan population.
  
  
  METHODS
  The Y-chromosomal STR loci were analyzed from 126 healthy unrelated autochthonous male individuals of Chinese Tibetan using a multiplex PCR system. Allele and haplotype frequencies for these loci were determined by the AmpFISTR Y filer PCR Amplification kit.
  
  
  RESULTS
  One hundred and twenty-one alleles were detected from the 14 STR loci. The allele diversity values (DP) for each locus ranged from 0.4104 (DYS391) to 0.9489 (DYS385a, b), the DP value of these loci were higher than 0.5 except for that of DYS391. A total of 105 haplotypes were identified in the Y-STR loci, among which 103 were unique, while two occurred more than once. The overall haplotype diversity for the Y-STR loci was 0.9998, and the discrimination capacity was 0.9898.
  
  
  CONCLUSIONS
  The 14 STR loci above belong to loci of high discriminating ability, the haplotypes are highly polymorphic.
authors.affiliation: Medical College, Tibet University, Lasa, Tibet, 850000 PR China.
authors.forename: Jian-min
authors.initials: JM
authors.lastname: Zhao
authors.forename: Dong-ya
authors.initials: DY
authors.lastname: Yuan
authors.forename: Long-li
authors.initials: LL
authors.lastname: Kang
authors.forename: Kai
authors.initials: K
authors.lastname: Liu
authors.forename: Sheng-bin
authors.initials: SB
authors.lastname: Li
mesh_terms: D000483:Alleles; D041322:Chromosomes, Human, Y / Q000235:genetics*; D005787:Gene Frequency; D006239:Haplotypes / Q000235:genetics*; D006801:Humans; D008297:Male; D018895:Microsatellite Repeats / Q000235:genetics*; D011110:Polymorphism, Genetic / Q000235:genetics*; D018609:Tibet