title: Richter transformation of chronic lymphocytic leukemia presenting as a dural-based non-hodgkin lymphoma mass.
abstract: Richter transformation is defined as a diffuse large cell lymphoma, occurring by transformation of chronic lymphocytic leukemia (CLL). We present a 64-year-old man with a history of CLL and a left parieto-occipital transtentorial extra-axial mass. The patient underwent CT and MR imaging, demonstrating a large dural-based mass with extracranial extension, which occluded the left transverse sinus. Biopsy of the mass proved a pathologic diagnosis of diffuse large cell non-Hodgkin lymphoma, consistent with Richter transformation of CLL.
authors.affiliation: Department of Radiology, Aultman Hospital, Canton, Ohio, USA. mohsen_48@yahoo.com
authors.forename: M
authors.initials: M
authors.lastname: Ghofrani
authors.forename: B
authors.initials: B
authors.lastname: Tantiwongkosi
authors.forename: A S
authors.initials: AS
authors.lastname: Smith
authors.forename: D A
authors.initials: DA
authors.lastname: Wasdahl
mesh_terms: D001932:Brain Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology; D002471:Cell Transformation, Neoplastic; D004388:Dura Mater / Q000000981:diagnostic imaging / Q000473:pathology; D017809:Fatal Outcome; D006801:Humans; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000000981:diagnostic imaging / Q000473:pathology*; D016403:Lymphoma, Large B-Cell, Diffuse / Q000000981:diagnostic imaging / Q000473:pathology*; D008228:Lymphoma, Non-Hodgkin / Q000000981:diagnostic imaging / Q000473:pathology*; D008279:Magnetic Resonance Imaging; D008297:Male; D008577:Meningeal Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D008875:Middle Aged; D012888:Skull Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology; D014057:Tomography, X-Ray Computed