[Mandibular chloroma].
METHODS
A 23 year-old girl was admitted for a facial tumefaction, fixed to the mandible. The X-rays showed a fuzzy osteolytic lesion of the mandibular angle. The CT-scan confirmed the rupture of the cortical bone and the extension to the soft tissue. Biopsy provided the diagnosis of granulocytic monoblastic sarcoma (chloroma). Chemotherapy was efficient.


CONCLUSIONS
Mandibular localizations of chloroma are rare. Granulocytic monoblastic sarcoma is a localized tumor made of extramedullar immature granulocytes, in general associated (or more rarely preceded by) with leukemia. Early diagnosis is important because high dose chemotherapy induction may completely cure leukemia.
Rysanek
B
B
Service de chirurgie maxillofaciale et stomatologie du Professeur Compère, CHU Côte de Nacre, 14033 Caen cedex, France.
Nicolas
J
J
Alix
T
T
Boutard
P
P
Minckes
O
O
Jeanne-Pasquier
C
C
Bénateau
H
H
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D003561:Cytarabine / Q000008:administration & dosage; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007223:Infant; D008339:Mandibular Neoplasms / Q000188:drug therapy / Q000473:pathology*; D008727:Methotrexate / Q000008:administration & dosage; D008775:Methylprednisolone / Q000008:administration & dosage; D008942:Mitoxantrone / Q000008:administration & dosage; D023981:Sarcoma, Myeloid / Q000188:drug therapy / Q000473:pathology*
D003561:Cytarabine; D008942:Mitoxantrone; D008775:Methylprednisolone; D008727:Methotrexate