Initial experience with a donor egg bank.
OBJECTIVE
To report on the establishment of a commercial donor egg bank (CryoEggs International, LP) and to present our initial experience from the first four patients to receive eggs.


METHODS
Case report.


METHODS
Private fertility clinic.


METHODS
The four recipient women were aged 43, 43, 40, and 33 years. All had cycle day FSH levels greater than 25 mIU/mL. All were given the option of fresh donor egg IVF but opted to use frozen donor oocytes.


METHODS
Purchased and quarantined frozen donor eggs were thawed and inseminated using intracytoplasmic sperm injection (ICSI). Subsequent embryos were transferred on day 3.


METHODS
Clinical pregnancy as defined by presence of cardiac activity.


RESULTS
There was a thawed egg survival rate of 76%, a fertilization rate of 74%, a pregnancy rate (PR) of 50%, with an average of 2.75 embryos per transfer and an implantation rate of 27%.


CONCLUSIONS
Although very preliminary, these results indicate that more widespread use of frozen donor eggs obtained from a commercial egg bank may be feasible in the future, changing the landscape of donor egg IVF.
Akin
James W
JW
Department of Obstetrics and Gynecology, University of Kentucky College of Medicine, Lexington, Kentucky, USA. jakin94939@aol.com
Bell
Katrina A
KA
Thomas
Diana
D
Boldt
Jeffrey
J
D000328:Adult; D002470:Cell Survival; D010064:Embryo Implantation; D005260:Female; D006801:Humans; D010063:Ovum / Q000166:cytology / Q000637:transplantation; D011247:Pregnancy; D018873:Pregnancy Rate; D020554:Sperm Injections, Intracytoplasmic / Q000379:methods*; D014015:Tissue Banks; D014019:Tissue Donors