title: A combined haemodynamic and biochemical model of cerebral autoregulation.
abstract: The feedback processes that control the blood supply to the brain, collectively termed cerebral autoregulation, are many and complex. Failure of this mechanism is implicated in a number of conditions. However, in a clinical setting the number of variables that can be measured non-invasively is extremely limited. In addition, current models are either too crude, and not physiologically meaningful, or so complex that analysis is difficult. In this paper a new compact, but physiologically meaningful, model is presented, based on smooth muscle cells within a vessel model, integrated within a full haemodynamic model. Preliminary results show realistic behaviour.
authors.affiliation: Dept. of Eng. Sci., Oxford Univ.
authors.forename: Stephen
authors.initials: S
authors.lastname: Payne
authors.forename: Henry
authors.initials: H
authors.lastname: Morris
authors.forename: Alexander
authors.initials: A
authors.lastname: Rowley