title: Optimization of Off-null Ellipsometry for Optical Biosensor Applications.
abstract: The optimization of off-null ellipsometry is described with emphasis on the improvement of resolution for visualizing biomolecule layers. For optical biosensor with layer thickness below 6.5 nm, a numerical simulation for the dependence of resolution on the azimuth settings of polarizer and analyzer is presented first. For comparison, three different resolutions are given at three azimuth settings which are near null and far away from null condition, respectively. Furthermore, the square or linear approximation relationship between the intensity and the layer thickness are also given at these settings. The difference among their accuracy is up to 100 times or so. Experimental results of the biosensor sample verify the optimization.
authors.affiliation: Institute of Mechanics, Chinese Academy of Sciences, #15, Bei-si-huan west Rd., Beijing 100080, P.R. China; Graduate School of Chinese Academy of Sciences, #19, Yu-quan Rd, Shi-jing-shan District, Beijing 100039, P.R. China.
authors.forename: Yanyan
authors.initials: Y
authors.lastname: Chen
authors.forename: Yonghong
authors.initials: Y
authors.lastname: Meng
authors.forename: Gang
authors.initials: G
authors.lastname: Jin