title: Characterization of carotid atherosclerosis based on motion and texture features and clustering using fuzzy c-means.
abstract: Analysis of B-mode ultrasound images of the carotid atheromatous plaque includes the estimation of texture from static images and the estimation of motion from image sequences. The combination of these two types of information may be valuable for accurate diagnosis of vascular disease. The purpose of this paper was to study texture and motion patterns of carotid atherosclerosis and select the optimal combination of features that can characterize plaque. B-mode ultrasound images of 10 symptomatic and 9 asymptomatic plaques were interrogated. A total of 99 texture features were estimated using first-order statistics, second-order statistics, Laws texture energy and the fractal dimension. Only five texture features were significantly different between the two groups. In the same subjects, the motion of selected plaque regions was estimated using region tracking and block-matching and expressed through: a/maximal surface velocity (MSV), and b/maximal relative surface velocity (MRSV). MSV and MRSV were significantly lower in asymptomatic plaques suggesting more homogeneous motion patterns. Clustering using fuzzy c-means correctly classified 74% of plaques based on texture features only, and 79% of plaques based on motion features only. Classification performance reached 84% when a combination of motion and texture features was used.
authors.affiliation: Dept. of Electr. & Comput. Eng., Nat. Tech. Univ. of Athens, Greece.
authors.forename: J
authors.initials: J
authors.lastname: Stoitsis
authors.forename: S
authors.initials: S
authors.lastname: Golemati
authors.forename: K S
authors.initials: KS
authors.lastname: Nikita
authors.forename: A N
authors.initials: AN
authors.lastname: Nicolaides