CuI-catalyzed suzuki-miyaura and sonogashira cross-coupling reactions using DABCO as ligand.
In the presence of TBAB, CuI-catalyzed Suzuki-Miyaura cross-coupling of vinyl halides and aryl halides with arylboronic acids was conducted smoothly to afford the corresponding diarylethenes and polyaryls in moderate to good yields using DABCO (1,4-diazabicyclo[2.2.2]octane) as the ligand. We also found that the inexpensive CuI/DABCO catalytic system was effective for Sonogashira cross-couplings of aryl halides and vinyl halides. A variety of aryl halides and vinyl halides including activated aryl chlorides underwent the coupling with terminal alkynes in moderate to excellent yields.
Li
Jin-Heng
JH
Key Laboratory of Chemical Biology & Traditional Chinese Medicine Research (Ministry of Education), College of Chemistry and Chemical Engineering, Hunan Normal University, Changsha 410081, China. jhli@hunnu.edu.cn
Li
Ji-Lan
JL
Wang
De-Ping
DP
Pi
Shao-Feng
SF
Xie
Ye-Xiang
YX
Zhang
Man-Bo
MB
Hu
Xi-Chao
XC
D000480:Alkynes / Q000737:chemistry; D002384:Catalysis; D003300:Copper / Q000737:chemistry; D003432:Cross-Linking Reagents / Q000737:chemistry; D006219:Halogens / Q000737:chemistry; D006841:Hydrocarbons, Aromatic / Q000737:chemistry; D008024:Ligands; D010879:Piperazines / Q000737:chemistry*
D000480:Alkynes; D003432:Cross-Linking Reagents; D006219:Halogens; D006841:Hydrocarbons, Aromatic; D008024:Ligands; D010879:Piperazines; D003300:Copper; C030973:cupric oxide; C007306:triethylenediamine