title: Intramolecular PIFA-mediated alkyne amidation and carboxylation reaction.
abstract: The hypervalent iodine reagent PIFA promotes the intramolecular electrophilic cyclization of easily accessible alkynylamides and alkynyl carboxylic acids, leading to the formation of pyrrolidinone and lactone skeletons, respectively, in a very efficient way. A synthetic study and a mechanistic proposal for these transformations are presented.
authors.affiliation: Departamento de Química Orgánica II, Facultad de Ciencia y Tecnología, Universidad del País Vasco/Euskal Herriko Unibertsitatea (UPV/EHU), P.O. Box 644, 48080 Bilbao, Spain. imanol.tellitu@ehu.es
authors.forename: Imanol
authors.initials: I
authors.lastname: Tellitu
authors.forename: Sonia
authors.initials: S
authors.lastname: Serna
authors.forename: M Teresa
authors.initials: MT
authors.lastname: Herrero
authors.forename: Isabel
authors.initials: I
authors.lastname: Moreno
authors.forename: Esther
authors.initials: E
authors.lastname: Domínguez
authors.forename: Raul
authors.initials: R
authors.lastname: SanMartin