title: Structure and strength at the bonding interface of a titanium-segmented polyurethane composite through 3-(trimethoxysilyl) propyl methacrylate for artificial organs.
abstract: The objective of this study was to investigate the structure and strength at the bonding interface of a titanium (Ti)-segmented polyurethane (SPU) composite through (3-trimethoxysilyl) propyl methacrylate (gamma-MPS) for artificial organs. The effects of the thickness of the gamma-MPS layer on the shear bonding strength between Ti and SPU were investigated. Ti disks were immersed in various concentrations of gamma-MPS solutions for several immersion times. The depth profiles of elements and the thickness of the gamma-MPS layer were determined by glow discharge optical emission spectroscopy and ellipsometry, respectively. The bonding stress at the Ti/gamma-MPS/SPU interface was evaluated with a shear bonding test. Furthermore, the fractured surface of a Ti-SPU composite was observed by optical microscopy and characterized using X-ray photoelectron spectroscopy. Consequently, the thickness of the gamma-MPS layer was controlled by the concentration of the gamma-MPS solution and immersion time. The shear bonding stress at the interface increased with the increase of the thickness of the gamma-MPS layer. Therefore, the control of the thickness of the gamma-MPS layer is significant to increase the shear bonding stress at the Ti/gamma-MPS/SPU interface. These results are significant to create composites for artificial organs consisting of other metals and polymers.
authors.affiliation: Department of Metallurgy, Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, Tokyo 101-0062, Japan.
authors.forename: Harumi
authors.initials: H
authors.lastname: Sakamoto
authors.forename: Hisashi
authors.initials: H
authors.lastname: Doi
authors.forename: Equo
authors.initials: E
authors.lastname: Kobayashi
authors.forename: Takayuki
authors.initials: T
authors.lastname: Yoneyama
authors.forename: Yoshiaki
authors.initials: Y
authors.lastname: Suzuki
authors.forename: Takao
authors.initials: T
authors.lastname: Hanawa
mesh_terms: D001187:Artificial Organs; D001672:Biocompatible Materials / Q000737:chemistry*; D001696:Biomechanical Phenomena; D020099:Coated Materials, Biocompatible / Q000737:chemistry; D006801:Humans; D066298:In Vitro Techniques; D008422:Materials Testing; D008689:Methacrylates / Q000737:chemistry; D017646:Organosilicon Compounds / Q000737:chemistry; D011140:Polyurethanes / Q000737:chemistry; D013057:Spectrum Analysis; D014025:Titanium / Q000737:chemistry; D014965:X-Rays
chemical_list: D001672:Biocompatible Materials; D020099:Coated Materials, Biocompatible; D008689:Methacrylates; D017646:Organosilicon Compounds; D011140:Polyurethanes; D014025:Titanium; C505504:3-(trimethoxysilyl)propyl methacrylate