Gene therapy of liver cancer.
Gene therapy of liver cancer covers a variety of gene transfer strategies aimed to the treatment of patients with primary and secondary liver tumors, including gene directed enzyme/pro-drug therapy, inhibition of oncogenes and restoration of tumor-suppressor genes, immunotherapy, anti-angiogenesis and virotherapy. Some of these strategies have reached early clinical development with diverse little success.
Hernández-Alcoceba
Rubén
R
Division of Gene Therapy and Hepatology, Foundation for Applied Medical Research-CIMA, University of Navarra, Pamplona, Spain.
Sangro
Bruno
B
Prieto
Jesús
J
D006528:Carcinoma, Hepatocellular / Q000628:therapy*; D015316:Genetic Therapy / Q000379:methods*; D006801:Humans; D008113:Liver Neoplasms / Q000628:therapy*; D016896:Treatment Outcome