Measurement of airflow through a metered dose inhaler during MRI.
We designed, calibrated and tested a flow meter for use inside an MRI scanner for measuring airflow through a metered dose inhaler (MDI). Several flow measurement methods were analyzed and the differential pressure method was selected utilizing the inhaler as part of the sensor. Our system can measure respiratory flows during use enabling the relationships between flow rate, air flow resistance, inhaler design, and drug deposition to be measured.
Delanvar
Soheil
S
Department of Anesthesiology, University of Florida, Gainesville, FL, USA.
Schmalfuss
Ilona
I
Melker
Richard
R
van Oostrom
Johannes
J