title: [Pathogenesis and treatment of hemocoagulation disorders in an acute necrotic pancreatitis].
abstract: Results of investigation of content of activated protein C, Intercellular Adhesion Molecule -1 (ICAM-1) and interleukin (IL)--18 in the patients with an acute pancreatitis were presented. At the hospital attendance the concentration of IL-18, ICAM-1 increase and the activated protein C level lowering were noted. The strict immediate correlation connection between serum blood level of IL-18, ICAM-1 and hematocrit and the reverse one--between these mediators concentration and the activated protein C content--were noted during all period of observation.
authors.forename: A A
authors.initials: AA
authors.lastname: Pereiaslov
authors.forename: S M
authors.initials: SM
authors.lastname: Chuklin
authors.forename: M M
authors.initials: MM
authors.lastname: Posivnych
mesh_terms: D001778:Blood Coagulation Disorders / Q000209:etiology / Q000276:immunology / Q000628:therapy; D006801:Humans; D018836:Inflammation Mediators / Q000097:blood*; D018799:Intercellular Adhesion Molecule-1 / Q000097:blood*; D020382:Interleukin-18 / Q000097:blood*; D019283:Pancreatitis, Acute Necrotizing / Q000097:blood / Q000150:complications / Q000276:immunology; D011486:Protein C / Q000032:analysis*
chemical_list: D018836:Inflammation Mediators; D020382:Interleukin-18; D011486:Protein C; D018799:Intercellular Adhesion Molecule-1