Complicated hyaluronan patterns in skin: enlightenment by UVB?
Hyaluronan has a complex metabolism with rapid turnover in skin, with wide differences occurring in dermal and epidermal compartments. Analyses of acute UVB irradiation of skin, as documented in cultured human fibroblast and immortalized keratinocyte cell culture media, confirm that no simple patterns are present. A systematic approach has been initiated in the studies by Averbeck et al.
Stern
Robert
R
Department of Pathology, School of Medicine, and UCSF Comprehensive Cancer Center, University of California, San Francisco, California 94143-0511, USA. robert.stern@ucsf.edu
D000818:Animals; D002462:Cell Membrane / Q000378:metabolism; D002478:Cells, Cultured; D003470:Culture Media / Q000378:metabolism; D004187:Disaccharides / Q000737:chemistry; D005347:Fibroblasts / Q000378:metabolism; D006801:Humans; D006820:Hyaluronic Acid / Q000737:chemistry / Q000502:physiology*; D015603:Keratinocytes / Q000166:cytology* / Q000276:immunology*; D051379:Mice; D011108:Polymers / Q000737:chemistry; D012867:Skin / Q000166:cytology / Q000276:immunology*; D014466:Ultraviolet Rays
D003470:Culture Media; D004187:Disaccharides; D011108:Polymers; D006820:Hyaluronic Acid