title: Interactive neuromonitoring methods of cochlea and auditory nerve during induced hypoxia and nerve manipulation.
abstract: Methods and instrumentation were developed to monitor cochlea and auditory function during surgery. The system allows real time assessment of the cochlear function during auditory nerve manipulation. A specially designed optic probe, placed on the round window (RW) niche, enables simultaneous acquisition of cochlear blood flow (CBF) and electrocochleogram (ECochG). We developed the acquisition paradigms, signal processing methods and implement them in a computational platform. The neuromonitoring system performs an automatic extraction and analysis of cochlear microphonics (CM), compound action potentials (CAP) and sura mating potential (SP). The system uses envelope detection filters to detect the amplitude of the CM. The CAP signal is processed with zero phase shift spectral filters, tuned to enhance the action potential onset, which is sometimes embedded within the sura mating potential. An automatic peak detection and tracking algorithm is then applied to extract latency and amplitude of CAPs. Long-term assessment of the monitoring system was performed during experimental animal surgeries. The system allowed detailed study of the dynamics of CM, CAP and CBF during nerve manipulation and compression.
authors.affiliation: Dept. of Biomed. Eng., Miami Univ., Coral Gables, FL, USA.
authors.forename: J
authors.initials: J
authors.lastname: Bohorquez
authors.forename: O
authors.initials: O
authors.lastname: Ozdamar
authors.forename: K
authors.initials: K
authors.lastname: Morawski
authors.forename: F
authors.initials: F
authors.lastname: Telischi
authors.forename: R
authors.initials: R
authors.lastname: Delgado
authors.forename: E
authors.initials: E
authors.lastname: Yavuz