Richter transformation of chronic lymphocytic leukemia presenting as a dural-based non-hodgkin lymphoma mass.
Richter transformation is defined as a diffuse large cell lymphoma, occurring by transformation of chronic lymphocytic leukemia (CLL). We present a 64-year-old man with a history of CLL and a left parieto-occipital transtentorial extra-axial mass. The patient underwent CT and MR imaging, demonstrating a large dural-based mass with extracranial extension, which occluded the left transverse sinus. Biopsy of the mass proved a pathologic diagnosis of diffuse large cell non-Hodgkin lymphoma, consistent with Richter transformation of CLL.
Ghofrani
M
M
Department of Radiology, Aultman Hospital, Canton, Ohio, USA. mohsen_48@yahoo.com
Tantiwongkosi
B
B
Smith
A S
AS
Wasdahl
D A
DA
D001932:Brain Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology; D002471:Cell Transformation, Neoplastic; D004388:Dura Mater / Q000000981:diagnostic imaging / Q000473:pathology; D017809:Fatal Outcome; D006801:Humans; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000000981:diagnostic imaging / Q000473:pathology*; D016403:Lymphoma, Large B-Cell, Diffuse / Q000000981:diagnostic imaging / Q000473:pathology*; D008228:Lymphoma, Non-Hodgkin / Q000000981:diagnostic imaging / Q000473:pathology*; D008279:Magnetic Resonance Imaging; D008297:Male; D008577:Meningeal Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D008875:Middle Aged; D012888:Skull Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology; D014057:Tomography, X-Ray Computed