title: [Tanakan (EGb 761) in the therapy of mild cognitive impairment].
abstract: Mild Cognitive Impairment (MCI) means cognitive deterioration not yet causing disability or dementia. Aged patients with MCI constitute a group of high risk for Alzheimer disease and other types of dementia. Currently, there is no generally adopted approach to MCI management but medications with neuroprotective properties are presumed to be the most perspective. Presented are the results of a multicentral open-label clinical trial of vascular and neuroprotective drug tanakan (EGb 761). The study has shown the decrease of cognitive impairment, which was both clinically and statistically significant, in patients at early stages of vascular and neurodegenerative pathological process. Probable efficacy of long-term tanakan treatment in prevention of dementia is discussed.
authors.forename: N N
authors.initials: NN
authors.lastname: Iakhno
authors.forename: V V
authors.initials: VV
authors.lastname: Zakharov
authors.forename: A B
authors.initials: AB
authors.lastname: Lokshina
authors.forename: S I
authors.initials: SI
authors.lastname: Gavrilova
authors.forename: Ia B
authors.initials: IaB
authors.lastname: Fedorova
authors.forename: A V
authors.initials: AV
authors.lastname: Gustov
authors.forename: Iu A
authors.initials: IuA
authors.lastname: Korshunova
authors.forename: L A
authors.initials: LA
authors.lastname: Dziak
authors.forename: E V
authors.initials: EV
authors.lastname: Miziakina
authors.forename: M M
authors.initials: MM
authors.lastname: Odinak
authors.forename: A Iu
authors.initials: AIu
authors.lastname: Emelin
authors.lastname: PilipenkoP I
authors.forename: E V
authors.initials: EV
authors.lastname: Vostrikova
mesh_terms: D000544:Alzheimer Disease / Q000453:epidemiology; D003072:Cognition Disorders / Q000175:diagnosis / Q000188:drug therapy* / Q000453:epidemiology; D004334:Drug Administration Schedule; D005260:Female; D020441:Ginkgo biloba; D006801:Humans; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D010936:Plant Extracts / Q000627:therapeutic use*; D012720:Severity of Illness Index; D000096983:Ginkgo Extract
chemical_list: D010936:Plant Extracts; C063170:Ginkgo biloba extract; D000096983:Ginkgo Extract