[The prognostic value of thrombus precursor protein in the assessment of the probability for venous thrombosis recurrence after the completion of anticoagulatory therapy with warfarin].
The article contains data on venous thrombosis (VT) recurrence rate in patients with the first episode of thrombus formation after the completion of one-year therapy with warfarin. The investigation included study of the prognostic value of intravascular coagulation marker (thrombus precursor protein --TPP) for the risk of venous retrombosis. The study showed that a high TPP level at the end of standard therapy course with warfarin in patients who had the first episode of spontaneous venous thrombosis is a significant indicator of a possible thrombosis recurrence during the nearest two tears after treatment with anticoagulants.
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D000328:Adult; D000925:Anticoagulants / Q000008:administration & dosage / Q000627:therapeutic use*; D015415:Biomarkers / Q000097:blood; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D005337:Fibrin / Q000378:metabolism*; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D011379:Prognosis; D011446:Prospective Studies; D012307:Risk Factors; D055502:Secondary Prevention; D020246:Venous Thrombosis / Q000097:blood* / Q000188:drug therapy; D014859:Warfarin / Q000008:administration & dosage / Q000627:therapeutic use*
D000925:Anticoagulants; D015415:Biomarkers; C465961:thrombus precursor protein, human; D014859:Warfarin; D005337:Fibrin