title: Histological diagnosis of mediastinal lymph node metastases from renal cell carcinoma by endobronchial ultrasound-guided transbronchial needle aspiration.
abstract: Evaluation of mediastinal lymphadenopathy in patients with an intrathoracic nodule post malignancy is crucial for the determination of further treatment. Different radiological modalities are available for the detection of mediastinal lymph node metastases such as multidetector helical CT, PET-scan and PET-CT. However, tissue sampling is required for a firm diagnosis. A minimally invasive method of tissue sampling of mediastinal and hilar lymph nodes using direct real-time endobronchial ultrasound-guided transbronchial needle aspiration has been reported. This method is appropriate not only for cytodiagnosis but also for histological diagnosis. This current study reports a case of mediastinal lymph node metastases from renal cell carcinoma successfully diagnosed histologically by endobronchial ultrasound-guided transbronchial needle aspiration.
authors.affiliation: Department of Thoracic Surgery, Graduate School of Medicine, Chiba University, Chiba, Japan.
authors.forename: Takahiro
authors.initials: T
authors.lastname: Nakajima
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Yasufuku
authors.forename: Matthew
authors.initials: M
authors.lastname: Wong
authors.forename: Akira
authors.initials: A
authors.lastname: Iyoda
authors.forename: Makoto
authors.initials: M
authors.lastname: Suzuki
authors.forename: Yasuo
authors.initials: Y
authors.lastname: Sekine
authors.forename: Kiyoshi
authors.initials: K
authors.lastname: Shibuya
authors.forename: Kenzo
authors.initials: K
authors.lastname: Hiroshima
authors.forename: Toshihiko
authors.initials: T
authors.lastname: Iizasa
authors.forename: Takehiko
authors.initials: T
authors.lastname: Fujisawa
mesh_terms: D044963:Biopsy, Fine-Needle / Q000379:methods; D001999:Bronchoscopy; D002292:Carcinoma, Renal Cell / Q000000981:diagnostic imaging* / Q000556:secondary; D003937:Diagnosis, Differential; D019160:Endosonography; D006801:Humans; D007680:Kidney Neoplasms / Q000473:pathology*; D008198:Lymph Nodes / Q000000981:diagnostic imaging / Q000473:pathology*; D008207:Lymphatic Metastasis; D008297:Male; D008482:Mediastinum; D008875:Middle Aged