Syntheses of novel chiral sulfinamido ligands and their applications in diethylzinc additions to aldehydes.
A novel class of sulfinamido alcohol ligands 1-6 was synthesized from (S)-tert-butanesulfinamide. These ligands showed excellent catalytic activities and enantiomeric selectivities in asymmetric additions of diethylzinc to aromatic aldehydes.
Huang
Zhiyan
Z
Department of Chemistry of Medicinal Natural Products and Key Laboratory of Drug Targeting, West China School of Pharmacy, Sichuan University, Chengdu 610041, P. R. China.
Lai
Hongshan
H
Qin
Yong
Y
D000447:Aldehydes / Q000737:chemistry*; D008024:Ligands; D009942:Organometallic Compounds / Q000737:chemistry*; D013452:Sulfonium Compounds / Q000737:chemistry*
D000447:Aldehydes; D008024:Ligands; D009942:Organometallic Compounds; D013452:Sulfonium Compounds; C518781:(S)-tert-butanesulfinamide; C454811:diethylzinc