title: Cytotoxic and antiprotozoal activity of flavonoids from Lonchocarpus spp.
abstract: A number of flavonoids isolated from Lonchocarpus spp. were evaluated for their antiprotozoal and cytotoxic activity. Flavone 6 and chalcone 7 were found to be the most active against Leishmania parasites and against cell cultures of Leukemia P388DI and adenocarcinoma prostate PC-3.
authors.affiliation: Centro de Investigación Científica de Yucatán, Calle 43 No 130 Chuburná, Mérida, Yucatán, México.
authors.forename: R
authors.initials: R
authors.lastname: Borges-Argáez
authors.forename: L
authors.initials: L
authors.lastname: Balnbury
authors.forename: A
authors.initials: A
authors.lastname: Flowers
authors.forename: A
authors.initials: A
authors.lastname: Giménez-Turba
authors.forename: G
authors.initials: G
authors.lastname: Ruiz
authors.forename: P G
authors.initials: PG
authors.lastname: Waterman
authors.forename: L M
authors.initials: LM
authors.lastname: Peña-Rodríguez
mesh_terms: D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000494:pharmacology* / Q000633:toxicity; D000981:Antiprotozoal Agents / Q000737:chemistry / Q000494:pharmacology* / Q000633:toxicity; D002453:Cell Cycle / Q000187:drug effects*; D045744:Cell Line, Tumor; D029866:Derris / Q000737:chemistry*; D047309:Flavones / Q000737:chemistry / Q000494:pharmacology* / Q000633:toxicity; D006801:Humans; D007938:Leukemia / Q000473:pathology; D008297:Male; D015394:Molecular Structure; D008517:Phytotherapy; D011471:Prostatic Neoplasms / Q000473:pathology
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D000981:Antiprotozoal Agents; D047309:Flavones