title: Predictive models for long term survival after premature rupture of membranes.
abstract: Premature rupture of the membranes complicates 30 to 40% of the preterm deliveries. The purpose of this study is to assess the outcome of preterm prelabor rupture of the membranes (PPROM) before 26 weeks of gestation and to develop a predictive model for survival. We apply four statistical methods in order to construct a predictive model: Cox's proportional hazards model, logistic regression, least squares - support vector machines and generalized estimating equations. The obtained predictive models are tested on a prospective set and have a very good performance of > 95% for the area under the ROC-curve.
authors.affiliation: Dept. of Electr. Eng., Katholieke Univ., Leuven, Heverlee.
authors.forename: Lieveke
authors.initials: L
authors.lastname: Ameye
authors.forename: Jos
authors.initials: J
authors.lastname: De Brabanter
authors.forename: Johan
authors.initials: J
authors.lastname: K Suykens
authors.forename: Isabelle
authors.initials: I
authors.lastname: Cadron
authors.forename: Roland
authors.initials: R
authors.lastname: Devlieger
authors.forename: Dirk
authors.initials: D
authors.lastname: Timmerman
authors.forename: Bernard
authors.initials: B
authors.lastname: Spitz
authors.forename: Sabine
authors.initials: S
authors.lastname: Van Huffel