title: Humoral hypercalcemia of penile carcinoma.
abstract: Hypercalcemia is a common life-threatening complication associated with several genitourinary malignancies. Parathyroid-related peptide has been shown to cause hypercalcemia in several solid tumors but rarely in penile cancer. We report a case of advanced penile cancer with hypercalcemia and associated dysphagia. Treatment is clinically challenging and should be definitive as soon as the patient has been stabilized. Serum calcium measurement can be used for monitoring the outcome and follow-up in such patients. Dysphagia is a rare but potential symptom of hypercalcemia, but additional studies are needed to prove this association.
authors.affiliation: Bro Morgannwg National Health Systems Trust, Princess of Wales Hospital, Bridgend, United Kingdom. rayyathurai@gmail.com
authors.forename: Rajinikanth
authors.initials: R
authors.lastname: Ayyathurai
authors.forename: David B
authors.initials: DB
authors.lastname: Webb
authors.forename: Susan
authors.initials: S
authors.lastname: Rowland
authors.forename: Timothy P
authors.initials: TP
authors.lastname: Stephenson
authors.forename: Andrew J
authors.initials: AJ
authors.lastname: Thomas
mesh_terms: D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000150:complications*; D006801:Humans; D006934:Hypercalcemia / Q000209:etiology*; D008297:Male; D010412:Penile Neoplasms / Q000150:complications*