title: Multisite microelectrode arrays for measurements of multiple neurochemicals.
abstract: Multisite microelectrode arrays designed for electrochemical measures of neurochemicals in CNS tissues are presented. The arrays have platinum recording sites insulated with polyimide on a ceramic substrate. Most designs include 4 recording sites, however arrays with 5 to 8 recording sites have been fabricated. Enzyme coatings have been developed to measure glutamate, choline, lactate, and glucose. Electroactive compounds such as dopamine, norepinephrine, and O/sub 2/ can also be measured. The multiple recording sites can be exploited for interferent or noise removal and measures of multiple compounds using a single microelectrode array.
authors.affiliation: Morris K. Udall Parkinson's Disease Research Center of Excellence, Kentucky University, Lexington, KY, USA.
authors.forename: J J
authors.initials: JJ
authors.lastname: Burmeister
authors.forename: T D
authors.initials: TD
authors.lastname: Coates
authors.forename: G A
authors.initials: GA
authors.lastname: Gerhardt