title: Patterns of venous reflux and obstruction in patients with skin damage due to chronic venous disease.
abstract: Identified were characteristics of individuals with skin damage related to chronic venous disease. Patients with chronic venous disease (n = 164) were evaluated with duplex ultrasound imaging and were placed in classes 4, 5, and 6 according to the CEAP classification. Their findings were compared with 100 class 2 controls. The prevalence of deep venous thrombosis was higher in the study group (23.7%) versus controls (5.1%; P < .0001), as was the prevalence of deep, perforator, and combined patterns of disease (P < .0001, P < .0007, and P < .0001). The mean duration of disease in controls 2 was shorter compared with the study group (P = .0019). The prevalence of reflux and obstruction within the study group was higher than in controls (P = .0021). Skin changes accurately reflect severity of chronic venous disease. Superficial and perforator vein reflux is the major cause of disease.
authors.affiliation: Department of Surgery, Loyola University Medical Center, Maywood, IL, USA. nlabrop@yahoo.com
authors.forename: Nicos
authors.initials: N
authors.lastname: Labropoulos
authors.forename: Parag J
authors.initials: PJ
authors.lastname: Patel
authors.forename: Jay E
authors.initials: JE
authors.lastname: Tiongson
authors.forename: Landon
authors.initials: L
authors.lastname: Pryor
authors.forename: Luis R
authors.initials: LR
authors.lastname: Leon
authors.forename: Apostolos K
authors.initials: AK
authors.lastname: Tassiopoulos
mesh_terms: D000328:Adult; D002908:Chronic Disease; D005260:Female; D006801:Humans; D007087:Illinois / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D011446:Prospective Studies; D012042:Registries; D012720:Severity of Illness Index; D012867:Skin / Q000473:pathology*; D013997:Time Factors; D018616:Ultrasonography, Doppler, Duplex; D014647:Varicose Ulcer / Q000453:epidemiology / Q000209:etiology* / Q000473:pathology; D014648:Varicose Veins / Q000150:complications* / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000503:physiopathology; D014689:Venous Insufficiency / Q000150:complications* / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000503:physiopathology; D020246:Venous Thrombosis / Q000150:complications* / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000503:physiopathology