Effects of Time-Varying Magnetic Fields on Transient increase in Intracellular Ca2+Concentration of Cultured Cells.
We tested the effects of some kinds of time-varying magnetic fields (0-1.2T) on neurotransmitter-induced transient increases in intracellular Ca2+concentration ([Ca2+]) of cultured chromaffin and HeLa cells. After these cells were exposed for 2 hours to these magnetic fields, transient increases in [Ca2+]i by addition of acetylcholine or histamine were measured. In control cells, after addition of these neurotransmitters [Ca2+]i was increased immediately and then decreased with time in both cells. But, addition of these drugs to the magnetic fields exposed cells increased [Ca2+]i to a level similar to that for control cells. These results suggest that the transient increases in [Ca2+]i were not significantly influenced by the magnetic fields used in this experiment.
Uchigami
Y
Y
Department of Electrical and Electronic Engineering, Faculty of Engineering, The University of Tokushima.
Kadowaki
N
N
Ikehara
T
T
Houchi
H
H
Yamaguchi
H
H
Yoshizaki
K
K
Miyamoto
H
H
Kinouchi
Y
Y