title: Interaction of halide and carboxylate ions with 4,5-diacetamidoacridine-9(10H)-one: thermodynamics of association and deprotonation events.
abstract: 4,5-Diacetamidoacridine-9(10H)-one was prepared, and its interactions with halide and benzoate anions were studied using a combination of NMR, fluorescence, and isothermal titration calorimetry experiments. Whereas chloride and bromide exhibited simple association, both fluoride and benzoate exhibited initial entropy-driven association followed by an enthalpically favorable deprotonation of the receptor by a second equivalent of the anion.
authors.affiliation: Department of Chemistry, Stony Brook University, Stony Brook, NY 11794, USA.
authors.forename: Chen
authors.initials: C
authors.lastname: Lin
authors.forename: Vladimir
authors.initials: V
authors.lastname: Simov
authors.forename: Dale G
authors.initials: DG
authors.lastname: Drueckhammer