Diffusion-weighted MR imaging of unusual white matter lesion in a patient with Menkes disease.
We report here on the diffusion-weighted imaging of unusual white matter lesions in a case of Menkes disease. On the initial MR imaging, the white matter lesions were localized in the deep periventricular white matter in the absence of diffuse cortical atrophy. The lesion showed diffuse high signal on the diffusion-weighted images and diffuse progression and persistent hyperintensity on the follow up imaging. Our case suggests that the white matter lesion may precede diffuse cortical atrophy in a patient with Menkes disease.
Lee
Eun Shin
ES
Department of Rehabilitation Medicine, Gyeongsang National University College of Medicine, Jinju 660-702, Korea.
Ryoo
Jae Wook
JW
Choi
Dae Seob
DS
Cho
Jae Min
JM
Kwon
Soo Hyun
SH
Shin
Hee Suk
HS
D001284:Atrophy; D001927:Brain Diseases / Q000175:diagnosis*; D003937:Diagnosis, Differential; D038524:Diffusion Magnetic Resonance Imaging; D006801:Humans; D007223:Infant; D008297:Male; D007706:Menkes Kinky Hair Syndrome / Q000175:diagnosis*