title: Fermentation and antimicrobial activities of extracts from different species of fungus belonging to Genus, Trichoderma.
abstract: The present paper discusses the effects of the crude extracts of Trichoderma spp. on a number of fungal and bacterial organisms. These include Paecilomyces variotii, Penicillium notatum, Nematospora corylii, Mucor miehei, Bacillus brevis, Bacillus subtilis, Enterobacter dissolvens and Sarcina lutea. The culture broth extracts of different isolates of Trichoderma harzianum, T. longibrachiatum and T. koningii cultured in different media were investigated individually for in-vitro antifungal and antibacterial activities by agar diffusion technique. The culture broth extracts of T. harzianum produced definite antifungal and antibacterial activities against most of the test organisms. The results indicate that the extracts were fungicidal and antibacterial at a concentration of 100 microg per 6mm paper disks. Trichoderma harzianum showed the highest activity while T. koningii showed the least activity against most of the test organisms especially the yeast Nematospora coryli. The results of this study indicate that the Trichoderma species especially T. harzianum is a possible source of useful antimicrobial agents against pathogenic microorganisms which include gram-negative, gram-positive, fungi and yeasts.
authors.affiliation: Chemistry Department, Kenyatta University, P.O. BOX 43844, Nairobi, Kenya. Tel.254 2 811581;Fax 254 2 811292; e-mail scchhabra@avu.org.
authors.forename: Paul K
authors.initials: PK
authors.lastname: Tarus
authors.forename: Sumesh C
authors.initials: SC
authors.lastname: Chhabra
authors.forename: Caroline
authors.initials: C
authors.lastname: Lang'at-Thoruwa
authors.forename: Alphonse W
authors.initials: AW
authors.lastname: Wanyonyi
mesh_terms: D000900:Anti-Bacterial Agents / Q000302:isolation & purification; D000890:Anti-Infective Agents; D000935:Antifungal Agents / Q000302:isolation & purification; D001412:Bacillus subtilis / Q000187:drug effects; D005285:Fermentation; D008826:Microbial Sensitivity Tests; D014242:Trichoderma / Q000187:drug effects
chemical_list: D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D000935:Antifungal Agents