title: Diffusion-weighted MR imaging of unusual white matter lesion in a patient with Menkes disease.
abstract: We report here on the diffusion-weighted imaging of unusual white matter lesions in a case of Menkes disease. On the initial MR imaging, the white matter lesions were localized in the deep periventricular white matter in the absence of diffuse cortical atrophy. The lesion showed diffuse high signal on the diffusion-weighted images and diffuse progression and persistent hyperintensity on the follow up imaging. Our case suggests that the white matter lesion may precede diffuse cortical atrophy in a patient with Menkes disease.
authors.affiliation: Department of Rehabilitation Medicine, Gyeongsang National University College of Medicine, Jinju 660-702, Korea.
authors.forename: Eun Shin
authors.initials: ES
authors.lastname: Lee
authors.forename: Jae Wook
authors.initials: JW
authors.lastname: Ryoo
authors.forename: Dae Seob
authors.initials: DS
authors.lastname: Choi
authors.forename: Jae Min
authors.initials: JM
authors.lastname: Cho
authors.forename: Soo Hyun
authors.initials: SH
authors.lastname: Kwon
authors.forename: Hee Suk
authors.initials: HS
authors.lastname: Shin
mesh_terms: D001284:Atrophy; D001927:Brain Diseases / Q000175:diagnosis*; D003937:Diagnosis, Differential; D038524:Diffusion Magnetic Resonance Imaging; D006801:Humans; D007223:Infant; D008297:Male; D007706:Menkes Kinky Hair Syndrome / Q000175:diagnosis*