title: A large scale synthesis of a natural antibiotic, 2,4-diacetylophloroglucinol (DAPG).
abstract: A natural antibiotic, 2,4-diacetylophloroglucinol (DAPG), has been prepared by the acetylation of phloroglucinol (PhL) with acetic anhydride in the presence of boron trifluoride etherate complex. The crude DAPG is efficiently purified using chromatographic filtration with boiling eluent.
authors.affiliation: Institute of Industrial Organic Chemistry, Warsaw, Poland. zakrzewski@ipo.waw.pl
authors.forename: Jerzy
authors.initials: J
authors.lastname: Zakrzewski
authors.forename: Monika
authors.initials: M
authors.lastname: Karpińska
authors.forename: Zbigniew
authors.initials: Z
authors.lastname: Maliński
mesh_terms: D000900:Anti-Bacterial Agents / Q000138:chemical synthesis* / Q000737:chemistry; D010696:Phloroglucinol / Q000031:analogs & derivatives / Q000138:chemical synthesis / Q000737:chemistry
chemical_list: D000900:Anti-Bacterial Agents; C059817:2,4-diacetylphloroglucinol; D010696:Phloroglucinol