Signaling netwErks get the global treatment.
Two landmark studies of cell signaling, by RNA interference and phosphoproteomics, provide complementary global views of the pathways downstream of receptor kinases, including those regulated by Erks.
Yaffe
Michael B
MB
Center for Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA. myaffe@mit.edu
White
Forest M
FM
D000818:Animals; D004789:Enzyme Activation; D048049:Extracellular Signal-Regulated MAP Kinases / Q000378:metabolism*; D040901:Proteomics; D034622:RNA Interference; D020794:Receptor Protein-Tyrosine Kinases / Q000378:metabolism; D015398:Signal Transduction
D020794:Receptor Protein-Tyrosine Kinases; D048049:Extracellular Signal-Regulated MAP Kinases