title: Paget's disease of the vulva--a review of our experience.
abstract: OBJECTIVE
  The aim of our study was to review our experience with Paget's disease of the vulvar relative to initial examination, treatment and oncological outcome.
  
  
  METHODS
  Ten women with extramammary Paget's diseases of the vulva were treated during the 10-year period. The charts of these patients were reviewed and data were collected regarding patient demographics, symptoms, previous Paget's disease, surgical treatments and time to recurrence.
  
  
  RESULTS
  Eight women (80%) were treated with wide local excision or partial vulvectomy, and two patients (20%) required radical resection for invasive adenocarcinoma. The group of women who had invasive diseases also underwent inquinofemoral lymphadenectomy and no lymphatic metastases were noted. Three women (30%) experienced recurrence. The mean time to relapse was 30 months (range 3-88 months).
  
  
  CONCLUSIONS
  Recurrence is very common and long-term monitoring is recommended with careful examination of any abnormal vulvar lesion.
authors.affiliation: Institute of Gynecology and Obstetrics, Clinical Center of Serbia, Belgrade (Serbia and Montenegro).
authors.forename: S
authors.initials: S
authors.lastname: Petković
authors.forename: K
authors.initials: K
authors.lastname: Jeremić
authors.forename: S
authors.initials: S
authors.lastname: Vidakovic
authors.forename: J
authors.initials: J
authors.lastname: Jeremić
authors.forename: G
authors.initials: G
authors.lastname: Lazović
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis / Q000601:surgery*; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008197:Lymph Node Excision; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000601:surgery*; D010145:Paget Disease, Extramammary / Q000150:complications / Q000175:diagnosis / Q000601:surgery*; D016896:Treatment Outcome; D007724:Vulvar Lichen Sclerosus; D014846:Vulvar Neoplasms / Q000150:complications / Q000175:diagnosis / Q000601:surgery*