title: The use of resorcine adhesive in repairing osteochondral's defect in knees of rabbits.
abstract: OBJECTIVE
  To study the morphology of the articulation of the knee of rabbits after the repairing of the defect osteochondral standardized with resorcina adhesive or metallic synthesis.
  
  
  METHODS
  The procedure was to the creation of the defect osteochondral in femoral medial condylus of the knee of 80 rabbits, The animals were distributed in two groups with continuations of 7 and 42 days and submitted to the technique G (resection and retreat of the fragment osteochondral of the femoral medial condylus and relocation with resorcina adhesive), technique S (resection and retreat of the fragment osteochondral of the femoral medial condylus and relocation and metallic synthesis) or technique C (resection and retreat of the fragment osteochondral of the femoral medial condylus, leaving the empty standard defect the control). It was Made clinical study, radiographic, macroscopic and histological in two groups.
  
  
  RESULTS
  the resorcina adhesive provokes: necrosis of the fragment osteochondral in 100% and 95%, degeneration 90% and 100%, free body in 80% and 65% respectively in the group I and II; compared with the metallic synthesis that it presented: necrosis in 25% and 35%, degeneration 25% and 35%, free body in 35% and 10% respectively in the group I and II.
  
  
  CONCLUSIONS
  the resorcinol adhesive, related with the necrosis, cartilaginous degeneration and detachment of the fragment osteochondral lives frequently that the metallic synthesis.
authors.affiliation: Department of Physiotherapy, University for Development of the State and the Pantanal Region, Campo Grande, Mato Grosso do Sul, Brazil.
authors.forename: Augusto Ken
authors.initials: AK
authors.lastname: Sakihama
authors.forename: Djalma José
authors.initials: DJ
authors.lastname: Fagundes
authors.forename: Celso Massaschi
authors.initials: CM
authors.lastname: Inouye
authors.forename: Ricardo Dutra
authors.initials: RD
authors.lastname: Aydos
authors.forename: Yara
authors.initials: Y
authors.lastname: Juliano
authors.forename: Juliano Coelho
authors.initials: JC
authors.lastname: Arakaki
authors.forename: Maçanori
authors.initials: M
authors.lastname: Odashiro
authors.forename: Paulo de Tarso Camilo de
authors.initials: Pde T
authors.lastname: Carvalho
mesh_terms: D000818:Animals; D002358:Cartilage, Articular / Q000187:drug effects / Q000473:pathology* / Q000601:surgery; D004338:Drug Combinations; D005557:Formaldehyde / Q000009:adverse effects*; D005592:Fracture Fixation; D005780:Gelatin / Q000009:adverse effects*; D007718:Knee Injuries / Q000473:pathology / Q000601:surgery; D008297:Male; D009336:Necrosis; D011817:Rabbits; D012118:Resorcinols / Q000009:adverse effects*; D014014:Tissue Adhesives / Q000009:adverse effects*; D014945:Wound Healing / Q000187:drug effects
chemical_list: D004338:Drug Combinations; D012118:Resorcinols; D014014:Tissue Adhesives; C027813:gelatin-resorcinol-formaldehyde tissue adhesive; D005557:Formaldehyde; D005780:Gelatin