title: BioInfer: a corpus for information extraction in the biomedical domain.
abstract: BACKGROUND
  Lately, there has been a great interest in the application of information extraction methods to the biomedical domain, in particular, to the extraction of relationships of genes, proteins, and RNA from scientific publications. The development and evaluation of such methods requires annotated domain corpora.
  
  
  RESULTS
  We present BioInfer (Bio Information Extraction Resource), a new public resource providing an annotated corpus of biomedical English. We describe an annotation scheme capturing named entities and their relationships along with a dependency analysis of sentence syntax. We further present ontologies defining the types of entities and relationships annotated in the corpus. Currently, the corpus contains 1100 sentences from abstracts of biomedical research articles annotated for relationships, named entities, as well as syntactic dependencies. Supporting software is provided with the corpus. The corpus is unique in the domain in combining these annotation types for a single set of sentences, and in the level of detail of the relationship annotation.
  
  
  CONCLUSIONS
  We introduce a corpus targeted at protein, gene, and RNA relationships which serves as a resource for the development of information extraction systems and their components such as parsers and domain analyzers. The corpus will be maintained and further developed with a current version being available at http://www.it.utu.fi/BioInfer.
authors.affiliation: Turku Centre for Computer Science (TUCS), University of Turku, Lemminkäisenkatu 14a, 20520 Turku, Finland. sampo.pyysalo@it.utu.fi
authors.forename: Sampo
authors.initials: S
authors.lastname: Pyysalo
authors.forename: Filip
authors.initials: F
authors.lastname: Ginter
authors.forename: Juho
authors.initials: J
authors.lastname: Heimonen
authors.forename: Jari
authors.initials: J
authors.lastname: Björne
authors.forename: Jorma
authors.initials: J
authors.lastname: Boberg
authors.forename: Jouni
authors.initials: J
authors.lastname: Järvinen
authors.forename: Tapio
authors.initials: T
authors.lastname: Salakoski
mesh_terms: D003628:Database Management Systems; D016208:Databases, Factual; D004282:Documentation / Q000379:methods*; D005796:Genes; D016247:Information Storage and Retrieval / Q000379:methods*; D009323:Natural Language Processing; D010506:Periodicals as Topic; D011506:Proteins / Q000145:classification*; D012313:RNA / Q000145:classification*; D009626:Terminology as Topic
chemical_list: D011506:Proteins; D012313:RNA