Predictors of naming decline after dominant temporal lobectomy: age at onset of epilepsy and age of word acquisition.
This study examined factors affecting object naming decline in patients who have undergone anterior temporal lobectomy (ATL) and the correlation between age of word acquisition and loss of specific object names postoperatively. The Boston Naming Test (BNT) was used to assess changes in object-naming performance in patients who underwent ATL. Correlation analyses were performed by group (dominant or nondominant ATL) on individual items from the BNT to determine if age of acquisition of object names had an effect on postoperative word loss. The influence of age at onset of seizures on naming decline was examined in the dominant ATL group. Only patients who had undergone dominant ATL experienced significant clinical and statistical declines after surgery. Among the patients who underwent dominant ATL, those with late age at onset of seizures declined significantly more than those with early-onset seizures. When individual object names were examined, age of acquisition of words predicted whether words were lost or gained after surgery.
Ruff
Ilana M
IM
Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA. iruff008@md.northwestern.edu
Swanson
Sara J
SJ
Hammeke
Thomas A
TA
Sabsevitz
David
D
Mueller
Wade M
WM
Morris
George L
GL
D000328:Adult; D017668:Age of Onset; D000375:Aging / Q000523:psychology*; D004827:Epilepsy / Q000523:psychology* / Q000601:surgery*; D005260:Female; D007839:Functional Laterality / Q000502:physiology; D006801:Humans; D007807:Language Tests; D007858:Learning / Q000502:physiology*; D008297:Male; D011183:Postoperative Complications / Q000523:psychology*; D011237:Predictive Value of Tests; D013702:Temporal Lobe / Q000601:surgery*; D014825:Vocabulary; D014888:Wechsler Scales