title: [Forensic pathological significance of immunohistochemical study with CX43 in rats on early myocardial ischaemia].
abstract: OBJECTIVE
  To explore one of evidence for pathologic diagnosis of early myocardial ischaemia.
  
  
  METHODS
  Rats were ligated of the left coronary artery according to a previously documented technique, and heart tissue was sampled at different ischaemia time. The expression of CX43 in myocardial cell was detected by Immunohistochemistry.
  
  
  RESULTS
  It is showed that the distribution and amount of CX43 positive staining in each group of the myocardial ischaemia was different from that of the control group.
  
  
  CONCLUSIONS
  The changes of CX43 detected by Immunohistochemical methods may be helpful for the diagnosis of early myocardial ischaemia, but further pathologic investigation and research is necessary.
authors.affiliation: Institute of Criminal Science, Hangzhou Public Security Bureau, Hangzhou 310031 China.
authors.forename: Li-fang
authors.initials: LF
authors.lastname: Jin
authors.forename: Ming-fang
authors.initials: MF
authors.lastname: Chen
authors.forename: Qiang
authors.initials: Q
authors.lastname: Zheng
authors.forename: Jing-yao
authors.initials: JY
authors.lastname: Xu
authors.forename: Yong-hao
authors.initials: YH
authors.lastname: Shen
authors.forename: You-fa
authors.initials: YF
authors.lastname: Zhu
mesh_terms: D000818:Animals; D018031:Connexin 43 / Q000378:metabolism*; D004195:Disease Models, Animal; D005260:Female; D049429:Forensic Pathology; D007150:Immunohistochemistry; D008297:Male; D017202:Myocardial Ischemia / Q000378:metabolism* / Q000473:pathology; D032383:Myocytes, Cardiac / Q000378:metabolism*; D009215:Myometrium / Q000378:metabolism / Q000473:pathology*; D011897:Random Allocation; D051381:Rats; D017207:Rats, Sprague-Dawley; D013194:Staining and Labeling; D013997:Time Factors; D014018:Tissue Distribution
chemical_list: D018031:Connexin 43