title: Y-chromosome genetic structure in sub-Apennine populations of Central Italy by SNP and STR analysis.
abstract: To define the Y-chromosome genetic structure in Apennine populations, 17 Y-chromosome short tandem repeats (Y-STRs) and 37 Y-single nucleotide polymorphisms (Y-SNPs) were typed in 162 subjects living in the upland area of the Marches (Central Italy). A total number of 155 haplotypes (haplotype diversity was 0.9994) and 14 SNP haplogroups were observed. Testing high-resolution Y-chromosome data sets, e.g. using Yfiler and SNPs, increases the discriminatory capacity in individual identification for forensic purposes. It is also useful in autochthonous population and micro-population studies to highlight the most informative loci for evolutionary aims.
authors.affiliation: Institute of Legal Medicine, Università Politecnica delle Marche, Ancona, Italy.
authors.forename: Valerio
authors.initials: V
authors.lastname: Onofri
authors.forename: Federica
authors.initials: F
authors.lastname: Alessandrini
authors.forename: Chiara
authors.initials: C
authors.lastname: Turchi
authors.forename: Barbara
authors.initials: B
authors.lastname: Fraternale
authors.forename: Loredana
authors.initials: L
authors.lastname: Buscemi
authors.forename: Mauro
authors.initials: M
authors.lastname: Pesaresi
authors.forename: Adriano
authors.initials: A
authors.lastname: Tagliabracci
mesh_terms: D041322:Chromosomes, Human, Y; D016172:DNA Fingerprinting; D005828:Genetics, Population; D006239:Haplotypes; D006801:Humans; D007558:Italy; D008297:Male; D016133:Polymerase Chain Reaction; D020641:Polymorphism, Single Nucleotide; D020080:Tandem Repeat Sequences