title: Extracellular concentration of anticancer drugs that regulates their intracellular distribution and binding to DNA in cells with multidrug resistant phenotype.
authors.affiliation: Blokhin Cancer Research Center, Russian Academy of Medical Science, Kashirskoe sh. 24, Moscow, 115478 Russia.
authors.forename: T A
authors.initials: TA
authors.lastname: Bogush
authors.forename: A B
authors.initials: AB
authors.lastname: Ravcheeva
authors.forename: E A
authors.initials: EA
authors.lastname: Bogush
authors.forename: A V
authors.initials: AV
authors.lastname: Konukhova
authors.forename: K E
authors.initials: KE
authors.lastname: Kuz'mina
authors.forename: A Y
authors.initials: AY
authors.lastname: Baryshnikov
authors.forename: M I
authors.initials: MI
authors.lastname: Davydov
mesh_terms: D020168:ATP Binding Cassette Transporter, Subfamily B, Member 1 / Q000378:metabolism; D018943:Anthracyclines / Q000494:pharmacology; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D000970:Antineoplastic Agents / Q000737:chemistry / Q000493:pharmacokinetics*; D002467:Cell Nucleus / Q000378:metabolism; D003593:Cytoplasm / Q000378:metabolism; D004247:DNA / Q000737:chemistry*; D004305:Dose-Response Relationship, Drug; D004317:Doxorubicin / Q000494:pharmacology; D004353:Drug Evaluation, Preclinical / Q000379:methods*; D018432:Drug Resistance, Multiple; D006801:Humans; D020014:K562 Cells; D010641:Phenotype; D011485:Protein Binding
chemical_list: D020168:ATP Binding Cassette Transporter, Subfamily B, Member 1; D018943:Anthracyclines; D000900:Anti-Bacterial Agents; D000970:Antineoplastic Agents; D004317:Doxorubicin; D004247:DNA