title: Megastigmanes and their glucosides from the whole plant of Sedum sarmentosum.
abstract: Two new megastigmanes, sarmentoic acid (1) and sarmentol A (2), and six new megastigmane glucosides, sedumosides A1 (3), A2 (4), A3 (5), B (6), C (7), and D (8), were isolated from the whole plant of Sedum sarmentosum together with eight known megastigmanes (9-16). The absolute stereostructures of 1-8 were elucidated on the basis of chemical and physicochemical evidence, including the application of the modified Mosher's method.
authors.affiliation: Kyoto Pharmaceutical University, Misasagi, Yamashina-ku, Kyoto 607-8412, Japan. myoshika@mb.kyoto-phn.ac.jp
authors.forename: Masayuki
authors.initials: M
authors.lastname: Yoshikawa
authors.forename: Toshio
authors.initials: T
authors.lastname: Morikawa
authors.forename: Yi
authors.initials: Y
authors.lastname: Zhang
authors.forename: Seikou
authors.initials: S
authors.lastname: Nakamura
authors.forename: Osamu
authors.initials: O
authors.lastname: Muraoka
authors.forename: Hisashi
authors.initials: H
authors.lastname: Matsuda
mesh_terms: D003512:Cyclohexanones / Q000737:chemistry / Q000302:isolation & purification*; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification*; D005960:Glucosides / Q000737:chemistry / Q000302:isolation & purification*; D015394:Molecular Structure; D045792:Norisoprenoids / Q000737:chemistry / Q000302:isolation & purification*; D010946:Plants, Medicinal / Q000737:chemistry*; D031963:Sedum / Q000737:chemistry*
chemical_list: D003512:Cyclohexanones; D004365:Drugs, Chinese Herbal; D005960:Glucosides; D045792:Norisoprenoids; C413264:megastigmane; C519743:sarmentoic acid; C519744:sarmentol A