title: HLA class I antigen and HLA-A, -B, and -C haplotype frequencies in Uruguayans.
abstract: HLA class I antigens were determined for 959 unrelated Uruguayans. The predominant HLA alleles were A2, Cw4, and B35, and the most frequently observed two-loci haplotypes were A2-B44 and B35-Cw4. The most frequent three-loci HLA haplotype was A2-Cw5-B44. We compared the Uruguayan sample with similar data from other populations.
authors.affiliation: Laboratorio de Inmunogenética e Histocompatibilidad, Instituto Nacional de Trasplante y Donación de Células, Tejidos y Organos (INDT), Hospital de Clinicas Manuel Quintela, Ave. Italia s/n Piso 4, CP 11600, Montevideo, Uruguay.
authors.forename: Ines
authors.initials: I
authors.lastname: Alvarez
authors.forename: Milka
authors.initials: M
authors.lastname: Bengochea
authors.forename: Roberto
authors.initials: R
authors.lastname: Toledo
authors.forename: Elena
authors.initials: E
authors.lastname: Carretto
authors.forename: Pedro C
authors.initials: PC
authors.lastname: Hidalgo
mesh_terms: D005787:Gene Frequency; D006680:HLA Antigens / Q000235:genetics*; D015234:HLA-A Antigens / Q000235:genetics; D015235:HLA-B Antigens / Q000235:genetics; D015236:HLA-C Antigens / Q000235:genetics; D006239:Haplotypes / Q000235:genetics*; D015395:Histocompatibility Antigens Class I / Q000235:genetics*; D006801:Humans; D014583:Uruguay
chemical_list: D006680:HLA Antigens; D015234:HLA-A Antigens; D015235:HLA-B Antigens; D015236:HLA-C Antigens; D015395:Histocompatibility Antigens Class I