title: Identification of prion inhibitors by a fluorescence-polarization-based competitive binding assay.
authors.affiliation: Laboratory of Persistent Viral Diseases, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT 59840, USA.
authors.forename: David A
authors.initials: DA
authors.lastname: Kocisko
authors.forename: Nadine
authors.initials: N
authors.lastname: Bertholet
authors.forename: Roger A
authors.initials: RA
authors.lastname: Moore
authors.forename: Byron
authors.initials: B
authors.lastname: Caughey
authors.forename: Andrew
authors.initials: A
authors.lastname: Vaillant
mesh_terms: D000818:Animals; D001665:Binding Sites; D001667:Binding, Competitive; D001681:Biological Assay; D002460:Cell Line; D006224:Cricetinae; D019793:Fluorescein / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology*; D005454:Fluorescence Polarization; D007700:Kinetics; D051379:Mice; D011328:Prions / Q000037:antagonists & inhibitors* / Q000378:metabolism; D011994:Recombinant Proteins / Q000378:metabolism; D012608:Scrapie / Q000188:drug therapy* / Q000378:metabolism
chemical_list: D011328:Prions; D011994:Recombinant Proteins; D019793:Fluorescein