Y-chromosome genetic structure in sub-Apennine populations of Central Italy by SNP and STR analysis.
To define the Y-chromosome genetic structure in Apennine populations, 17 Y-chromosome short tandem repeats (Y-STRs) and 37 Y-single nucleotide polymorphisms (Y-SNPs) were typed in 162 subjects living in the upland area of the Marches (Central Italy). A total number of 155 haplotypes (haplotype diversity was 0.9994) and 14 SNP haplogroups were observed. Testing high-resolution Y-chromosome data sets, e.g. using Yfiler and SNPs, increases the discriminatory capacity in individual identification for forensic purposes. It is also useful in autochthonous population and micro-population studies to highlight the most informative loci for evolutionary aims.
Onofri
Valerio
V
Institute of Legal Medicine, Università Politecnica delle Marche, Ancona, Italy.
Alessandrini
Federica
F
Turchi
Chiara
C
Fraternale
Barbara
B
Buscemi
Loredana
L
Pesaresi
Mauro
M
Tagliabracci
Adriano
A
D041322:Chromosomes, Human, Y; D016172:DNA Fingerprinting; D005828:Genetics, Population; D006239:Haplotypes; D006801:Humans; D007558:Italy; D008297:Male; D016133:Polymerase Chain Reaction; D020641:Polymorphism, Single Nucleotide; D020080:Tandem Repeat Sequences