Use of intraluminal protection in colonic anastomosis in dogs.
OBJECTIVE
To test the use of intraluminal protection in colonic anastomosis without intestinal cleansing. The intraluminal liner was fashioned from porcine submucosa preserved in glycerin and then fixed 10 cm anteriorly to the anastomotic site. This technique was compared with the one used in termino-terminal colonic anastomosis without intraluminal protection.


METHODS
Twenty-eight dogs were divided into two groups of fourteen animals each. Clinical and histopathological tests were performed on the fourth and twenty-first postoperative days.


RESULTS
The morbidity and mortality rates were higher in animals that did not receive the intraluminal liner. Histopathological examinations in animals in which the intraluminal liner was used showed better healing, characterized by milder inflammation and increased amount of collagen.


CONCLUSIONS
It can be concluded that the use of intraluminal protection decreases complication rates in colonic anastomosis and promotes better healing.
Oliveira
André Lacerda de Abreu
AL
Laboratory of Experimental Surgery, Department of Surgery, Federal University of Rio de Janeiro, 28010-400 Campus dos Goytacazes, RJ, Brazil. andrevet@uenf.br
Jamel
Nelson
N
Lacombe
Domingos Penna
DP
Gonçalves
Manuel Domingos
MD
Abílio
Edmundo Jorge
EJ
Manso
José Eduardo Ferreira
JE
Costa
Alessandra Castello da
AC
D000714:Anastomosis, Surgical / Q000009:adverse effects / Q000379:methods / Q000401:mortality; D000818:Animals; D003094:Collagen; D003106:Colon / Q000601:surgery*; D004285:Dogs; D005260:Female; D005990:Glycerol / Q000627:therapeutic use*; D007249:Inflammation; D007413:Intestinal Mucosa / Q000637:transplantation*; D023421:Models, Animal; D013529:Surgical Wound Dehiscence / Q000209:etiology; D013552:Swine; D014945:Wound Healing
D003094:Collagen; D005990:Glycerol