title: The value of Chlamydia trachomatis-specific IgG antibody testing and hysterosalpingography for predicting tubal pathology and occurrence of pregnancy.
abstract: We assessed two diagnostic methods, Chlamydia trachomatis-specific IgG and hysterosalpingography (HSG), as a screening test for the likelihood of tubal damage or occurrence of pregnancy before laparoscopy in 178 subfertile women who were randomly assigned to HSG followed by laparoscopy or immediate laparoscopy. The diagnostic accuracy and prognostic value of both C. trachomatis-specific IgG antibody testing and HSG are comparable but show poor performance.
authors.affiliation: Department of Obstetrics and Gynecology, Medical Center Haaglanden, The Hague, The Netherlands. dperquin@knoware.nl
authors.forename: Denise A M
authors.initials: DA
authors.lastname: Perquin
authors.forename: Matthias F C
authors.initials: MF
authors.lastname: Beersma
authors.forename: Anton J M
authors.initials: AJ
authors.lastname: de Craen
authors.forename: Frans M
authors.initials: FM
authors.lastname: Helmerhorst
mesh_terms: D000907:Antibodies, Bacterial / Q000097:blood; D002692:Chlamydia trachomatis / Q000276:immunology* / Q000302:isolation & purification; D005184:Fallopian Tube Diseases / Q000175:diagnosis* / Q000382:microbiology*; D005260:Female; D006801:Humans; D007047:Hysterosalpingography / Q000379:methods; D007074:Immunoglobulin G / Q000097:blood*; D010535:Laparoscopy / Q000009:adverse effects; D011237:Predictive Value of Tests; D011247:Pregnancy; D018873:Pregnancy Rate / Q000639:trends*; D011446:Prospective Studies
chemical_list: D000907:Antibodies, Bacterial; D007074:Immunoglobulin G