Epidemiological data and molecular characterization (mtDNA) of Sporothrix schenckii in 13 cases from Mexico.
BACKGROUND
Sporotrichosis is an endemic mycosis in Mexico and Central America.


OBJECTIVE
To present epidemiological data and characterize molecular subtypes of 13 strains of Sporothrix schenckii, and to correlate clinical and epidemiologic presentation with subtypes.


METHODS
Thirteen Mexican cases of sporotrichosis were identified, and mitochondrial DNA (mtDNA) from clinical isolates of S. schenckii were analyzed using RFLP Hae III. Molecular types 2, 3, 14, 28, and 29 were observed.


RESULTS
Clinical presentations and molecular types were consistent with established epidemiologic patterns for S. schenckii in this region.


CONCLUSIONS
This investigation provides further evidence of the strong regional specificity of molecular types of this organism.
Arenas
Roberto
R
Department of Dermatology, Dr. Manuel Gea Gonzalez General Hospital, Mexico City. rarenas98@hotmail.com
Miller
Daniel
D
Campos-Macias
Pablo
P
D000328:Adult; D000368:Aged; D002648:Child; D004272:DNA, Mitochondrial / Q000032:analysis*; D005260:Female; D006801:Humans; D008297:Male; D008800:Mexico; D008875:Middle Aged; D012150:Polymorphism, Restriction Fragment Length; D013175:Sporothrix / Q000145:classification / Q000235:genetics*; D013174:Sporotrichosis / Q000453:epidemiology* / Q000382:microbiology
D004272:DNA, Mitochondrial