The genomic era and serious mental illness: a potential application for psychiatric genetic counseling.
Genetic counseling is an important clinical service that is routinely offered to families affected by genetic disorders or by complex disorders for which genetic testing is available. It is not yet routinely offered to individuals with serious mental illnesses and their families, but recent findings that beliefs about the cause of mental illness can affect an individual's adaptation to the illness suggest that genetic counseling may be a useful intervention for this population. In a genetic counseling session the counselor discusses genetic and environmental contributors to disease pathogenesis; helps individuals explore conceptions, fears, and adaptive strategies; and provides nondirective support for decision making. Expected outcomes may include reductions in fear, stigma, and guilt associated with a psychiatric diagnosis; improvements in adherence to prescribed medications; declines in risk behaviors; and reductions in misconceptions about the illness. The authors endorse a multidisciplinary approach in which a psychiatrist and genetic counselor collaborate to provide comprehensive psychiatric genetic counseling.
Austin
Jehannine C
JC
Department of Psychiatry, University of British Columbia, 203-828 West 10th Ave., Vancouver, British Columbia, Canada V5Z 1L8. jcaustin@interchange.ubc.ca
Honer
William G
WG
D005817:Genetic Counseling; D020022:Genetic Predisposition to Disease / Q000235:genetics; D006167:Guilt; D006801:Humans; D010342:Patient Acceptance of Health Care / Q000523:psychology; D010348:Patient Care Team; D010353:Patient Education as Topic; D011287:Prejudice; D011618:Psychotic Disorders / Q000235:genetics* / Q000523:psychology; D012017:Referral and Consultation; D012307:Risk Factors; D012309:Risk-Taking