title: Gene therapy of liver cancer.
abstract: Gene therapy of liver cancer covers a variety of gene transfer strategies aimed to the treatment of patients with primary and secondary liver tumors, including gene directed enzyme/pro-drug therapy, inhibition of oncogenes and restoration of tumor-suppressor genes, immunotherapy, anti-angiogenesis and virotherapy. Some of these strategies have reached early clinical development with diverse little success.
authors.affiliation: Division of Gene Therapy and Hepatology, Foundation for Applied Medical Research-CIMA, University of Navarra, Pamplona, Spain.
authors.forename: Rubén
authors.initials: R
authors.lastname: Hernández-Alcoceba
authors.forename: Bruno
authors.initials: B
authors.lastname: Sangro
authors.forename: Jesús
authors.initials: J
authors.lastname: Prieto
mesh_terms: D006528:Carcinoma, Hepatocellular / Q000628:therapy*; D015316:Genetic Therapy / Q000379:methods*; D006801:Humans; D008113:Liver Neoplasms / Q000628:therapy*; D016896:Treatment Outcome