title: Institutional review board approval: why it matters.
abstract: The modern institutional review boards originated in the 1970s. They exist to protect human subjects participating in research from potential harm. The Belmont Report provided the ethical principles (respect for persons, beneficence, and justice) that should be observed while conducting research on human subjects. Compliance with the ethical principles of the Belmont Report is a first step in successful submissions to an institutional review board. Regulations regarding conflict of interest represent an attempt to ensure that research is not biased by financial or other interest and to maintain public trust.
authors.affiliation: Rothman Institute of Orthopedics at Thomas Jefferson University Hospital, 925 Chestnut Street, Philadelphia, PA 19107, USA. parvj@aol.com
authors.forename: Javad
authors.initials: J
authors.lastname: Parvizi
authors.forename: T David
authors.initials: TD
authors.lastname: Tarity
authors.forename: Kyle
authors.initials: K
authors.lastname: Conner
authors.forename: J Bruce
authors.initials: JB
authors.lastname: Smith
mesh_terms: D002568:Certification; D002985:Clinical Protocols; D016265:Conflict of Interest; D028744:Ethics Committees, Research / Q000941:ethics / Q000331:legislation & jurisprudence / Q000458:organization & administration; D020408:Health Insurance Portability and Accountability Act; D006805:Human Experimentation / Q000941:ethics*; D006801:Humans; D007258:Informed Consent; D011996:Records; D012109:Research Support as Topic; D014481:United States; D035862:Vulnerable Populations