Comparison of two enhanced consent procedures for patients with mild Alzheimer disease or mild cognitive impairment.
OBJECTIVE
The objective of this study was to evaluate the feasibility, acceptability, and preliminary efficacy of two enhanced consent procedures provided to patients with Alzheimer disease or mild cognitive impairment that used either a PowerPoint presentation or an enhanced printed consent form.


METHODS
Patients randomly assigned to an enhanced written consent procedure or slideshow presentation were assessed with the MacArthur Competence Assessment Tool for Clinical Research.


RESULTS
Verbal reexplanation was associated with improved understanding in both conditions. Level of understanding did not significantly differ between the two consent groups, but administration time for slideshow presentation was less than that for an enhanced written consent procedure.


CONCLUSIONS
Enhanced consent procedures are feasible and useful for consent to research among patients with mild cognitive impairment or mild Alzheimer disease.
Mittal
Dinesh
D
Center for Mental Healthcare and Outcomes Research, Central Arkansas Veterans Healthcare System, North Little Rock, Arkansas 72114, USA. dmittal@uams.edu
Palmer
Barton W
BW
Dunn
Laura B
LB
Landes
Reid
R
Ghormley
Courtney
C
Beck
Cornelia
C
Golshan
Shah
S
Blevins
Dean
D
Jeste
Dilip V
DV
D000368:Aged; D000369:Aged, 80 and over; D000544:Alzheimer Disease / Q000175:diagnosis* / Q000523:psychology; D001296:Audiovisual Aids; D002986:Clinical Trials as Topic / Q000523:psychology*; D003072:Cognition Disorders / Q000175:diagnosis* / Q000523:psychology; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D007258:Informed Consent / Q000523:psychology*; D008297:Male; D016743:Mental Competency; D011932:Reading