title: A feasible and quantitative encoding method for microbeads with multicolor quantum dots.
abstract: Multicolor encoded beads were achieved by incorporating two color core-shell quantum dots (QDs) (CdSe/ZnS) to commercial polystyrene (PS) beads. By controlling the concentration ratios of the two quantum dots (QDs) in doping solutions, a series of codes with different intensity ratios were obtained. Based on the multiple encoded carboxylic modified polystyrene beads, fluorescent dyes labeled antibodies were distinguished successfully on the beads' surface. It suggests that the encoded beads from this method have the practicability in biological applications and chemical analysis.
authors.affiliation: Key Laboratory of Biomedical Photonics of Ministry of Education-Hubei Bioinformatics and Molecular Imaging Key Laboratory, Huazhong University of Science and Technology, Wuhan, HuBei, 430074 PR China.
authors.forename: Hai-Qiao
authors.initials: HQ
authors.lastname: Wang
authors.forename: Zhen-Li
authors.initials: ZL
authors.lastname: Huang
authors.forename: Tian-Cai
authors.initials: TC
authors.lastname: Liu
authors.forename: Jian-Hao
authors.initials: JH
authors.lastname: Wang
authors.forename: Yuan-Cheng
authors.initials: YC
authors.lastname: Cao
authors.forename: Xiao-Feng
authors.initials: XF
authors.lastname: Hua
authors.forename: Xiu-Qing
authors.initials: XQ
authors.lastname: Li
authors.forename: Yuan-Di
authors.initials: YD
authors.lastname: Zhao
mesh_terms: D000906:Antibodies / Q000032:analysis; D019187:Cadmium Compounds / Q000737:chemistry; D005456:Fluorescent Dyes / Q000737:chemistry; D008856:Microscopy, Fluorescence / Q000379:methods*; D008863:Microspheres; D011137:Polystyrenes / Q000737:chemistry; D045663:Quantum Dots; D018036:Selenium Compounds / Q000737:chemistry; D013440:Sulfides / Q000737:chemistry; D017967:Zinc Compounds / Q000737:chemistry
chemical_list: D000906:Antibodies; D019187:Cadmium Compounds; D005456:Fluorescent Dyes; D011137:Polystyrenes; D018036:Selenium Compounds; D013440:Sulfides; D017967:Zinc Compounds; C058667:cadmium selenide; C031238:zinc sulfide