[Matching minor transplantation antigens in penetrating keratoplasty].
Specific recognition of foreign tissue is a common feature in higher vertebrates. This capability has commonly been ascribed to the human leukocyte antigen (HLA) complex. Recent developments, however, point to an outstanding role of minor H antigens, especially in the context of corneal transplantation. It is likely that the matching of selected minor H antigens will further improve rejection free, clear graft survival following penetrating keratoplasty in the not so distant future.
Spierings
E
E
Abteilung für Immunhämatologie und Bluttransfusion, Leiden University Medical Center, Leiden, Niederlande.
Reinhard
T
T
Goulmy
E
E
Böhringer
D
D
D000017:ABO Blood-Group System / Q000276:immunology; D001324:Autoantigens / Q000276:immunology*; D003316:Corneal Diseases / Q000276:immunology* / Q000601:surgery*; D016039:Corneal Transplantation / Q000276:immunology* / Q000379:methods; D006084:Graft Rejection / Q000276:immunology; D006085:Graft Survival / Q000276:immunology; D006680:HLA Antigens / Q000276:immunology*; D006650:Histocompatibility Testing / Q000379:methods*; D006801:Humans; D015948:Keratoplasty, Penetrating / Q000276:immunology* / Q000379:methods
D000017:ABO Blood-Group System; D001324:Autoantigens; D006680:HLA Antigens