title: Protein sequence database for pathogenic arenaviruses.
abstract: BACKGROUND
  Arenaviruses are a family of rodent-borne viruses that cause several hemorrhagic fevers. These diseases can be devastating and are often lethal. Herein, to aid in the design and development of diagnostics, treatments and vaccines for arenavirus infections, we have developed a database containing protein sequences from the seven pathogenic arenaviruses (Junin, Guanarito, Sabia, Machupo, Whitewater Arroyo, Lassa and LCMV).
  
  
  RESULTS
  The database currently contains a non-redundant set of 333 protein sequences which were manually annotated. All entries were linked to NCBI and cited PubMed references. The database has a convenient query interface including BLAST search. Sequence variability analyses were also performed and the results are hosted in the database.
  
  
  CONCLUSIONS
  The database is available at http://epitope.liai.org:8080/projects/arena and can be used to aid in studies that require proteomic information from pathogenic arenaviruses.
authors.affiliation: La Jolla Institute for Allergy and Immunology, Division of Vaccine Discovery, 9420 Athena Circle, La Jolla, CA 92037, USA. hbui@liai.org
authors.forename: Huynh-Hoa
authors.initials: HH
authors.lastname: Bui
authors.forename: Jason
authors.initials: J
authors.lastname: Botten
authors.forename: Nicolas
authors.initials: N
authors.lastname: Fusseder
authors.forename: Valerie
authors.initials: V
authors.lastname: Pasquetto
authors.forename: Bianca
authors.initials: B
authors.lastname: Mothe
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Buchmeier
authors.forename: Alessandro
authors.initials: A
authors.lastname: Sette