title: [Severe anterior myocardial infarction caused by amphetamine abuse].
abstract: We present a case showing that intake of amphetamine can cause severe anterior myocardial infarction with acute severe pump failure. Acute angiography revealed massive proximal thrombotic occlusion of the LAD, the first diagonal branch and septal branches in a 28-year-old man. Thrombectomy, balloon dilation and stenting were performed. Spasm thrombus interplay was found to be the likely mechanism. Due to the massive infarction, extremely depressed left ventricular performance and hemodynamic instability, the patient underwent successful heart transplantation. The patient was readmitted to hospital six months later due to chronic vascular rejection of the heart, which lead to the death of the young man.
authors.affiliation: Arhus Universitetshospital, Skejby Sygehus, Hjerte-lunge-karkirurgisk Afdeling T. lrz@post.tele.dk
authors.forename: Lars Peter Riber
authors.initials: LP
authors.lastname: Zebis
authors.forename: Thomas Decker
authors.initials: TD
authors.lastname: Christensen
authors.forename: Morten
authors.initials: M
authors.lastname: Bøttcher
authors.forename: Hans E
authors.initials: HE
authors.lastname: Eiskjaer
authors.forename: Anne-Grethe
authors.initials: AG
authors.lastname: Lorenzen
authors.forename: Lars B
authors.initials: LB
authors.lastname: Ilkjaer
authors.forename: Ulrik
authors.initials: U
authors.lastname: Baandrup
mesh_terms: D000328:Adult; D000661:Amphetamine / Q000009:adverse effects*; D019969:Amphetamine-Related Disorders / Q000150:complications*; D000697:Central Nervous System Stimulants / Q000009:adverse effects*; D017809:Fatal Outcome; D006084:Graft Rejection; D016027:Heart Transplantation; D006801:Humans; D008297:Male; D009203:Myocardial Infarction / Q000139:chemically induced* / Q000473:pathology / Q000601:surgery
chemical_list: D000697:Central Nervous System Stimulants; D000661:Amphetamine