Regioselectivity control of radiation-induced reaction: electron beam-induced fries rearrangement of sulfonamide within a beta-cyclodextrin inclusion complex.
EB (electron beam) irradiation of sulfonamide within a beta-cyclodextrin (beta-CD) inclusion complex in the solid state induced the solvent-free Fries rearrangement, which proceeded at a shorter reaction time with reversed regioselectivity by inclusion into the beta-CD, compared with that of sulfonamide crystals; the beta-CD as a restricted nanospace had a large effect on the reactivity and regioselectivity of the solvent-free EB-Fries rearrangement.
Kato
Jun
J
Department of Pure and Applied Chemistry, Tokyo University of Science, 2641 Yamazaki, Noda, Chiba, 278-8510, Japan. kato@rs.noda.tus.ac.jp
Kakehata
Hiroyuki
H
Maekawa
Yasunari
Y
Yamashita
Takashi
T