title: No association between 5-HTTLPR and harm avoidance in Korean college students.
abstract: There have been numerous studies on the association between 5-HTTLPR (polymorphisms in the promoter region of the serotonin transporter gene) and anxiety-related personality traits, with conflicting results. In this study, we administered Korean version of the Temperament and Character Inventory (K-TCI) to a sample of 158 Korean college students and genotyped for the 5-HTTLPR in order to compare the TCI dimensional scores including harm avoidance according to the 5-HTTLPR genotype and sex. We could not find the association between 5-HTTLPR and harm avoidance and other TCI measures. Considering known allele frequencies differences of 5-HTTLPR among different ethnic groups, further cross-cultural studies with a larger sample would be needed.
authors.affiliation: Department of Psychiatry, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
authors.forename: Yeon Ho
authors.initials: YH
authors.lastname: Joo
authors.forename: Heung Bum
authors.initials: HB
authors.lastname: Oh
authors.forename: Byungsu
authors.initials: B
authors.lastname: Kim
authors.forename: Suk Hoon
authors.initials: SH
authors.lastname: Jung
authors.forename: Jun Kyu
authors.initials: JK
authors.lastname: Chung
authors.forename: Jin Pyo
authors.initials: JP
authors.lastname: Hong
authors.forename: Chang Yoon
authors.initials: CY
authors.lastname: Kim
mesh_terms: D000328:Adult; D005106:Exploratory Behavior; D005260:Female; D005838:Genotype; D040261:Harm Reduction; D006801:Humans; D008297:Male; D010551:Personality; D050486:Serotonin Plasma Membrane Transport Proteins / Q000235:genetics*; D013694:Temperament
chemical_list: D050486:Serotonin Plasma Membrane Transport Proteins