Nebulised DNase in the treatment of life threatening asthma.
A 25-year-old pregnant patient developed life-threatening asthma refractory to all standard treatment including anaesthetic agents. Ventilatory pressures continued to rise with impending cardio-respiratory arrest. The introduction of nebulised endotracheal DNase however resulted in a rapid and dramatic improvement with good clinical outcome.
Hull
James H K
JH
Frimley Park Hospital NHS Foundation Trust, Camberley, Surrey, United Kingdom. jiminio@doctors.org.uk
Castle
Nick
N
Knight
Ronald K
RK
Ho
Timothy B L
TB
D000328:Adult; D001249:Asthma / Q000188:drug therapy*; D003851:Deoxyribonucleases / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D009330:Nebulizers and Vaporizers; D011247:Pregnancy; D016896:Treatment Outcome
D003851:Deoxyribonucleases