Cisplatin-induced hyperglycemic hyperosmolar coma.
We present a case of severe hyperglycaemic hyperosmolar derangement after treatment with cisplatin in a patient without previous diabetes mellitus. Limited data are available on this adverse reaction, explaining why impaired glucose handling due to cisplatin is not generally recognised.
Komdeur
R
R
Department of Internal Medicine, Medical Spectrum Twente Hospital, Enschede, the Netherlands. R.Komdeur@ziekenhuis-mst.nl
Derksen
J
J
Legdeur
M-C
MC
Hylkema
B S
BS
D000328:Adult; D000970:Antineoplastic Agents / Q000009:adverse effects*; D002945:Cisplatin / Q000009:adverse effects*; D006801:Humans; D006944:Hyperglycemic Hyperosmolar Nonketotic Coma / Q000139:chemically induced* / Q000175:diagnosis; D008297:Male
D000970:Antineoplastic Agents; D002945:Cisplatin