title: Mechanisms of action of statins in stroke.
abstract: Statins decrease the incidence of cardiovascular events and death in patients with coronary artery disease. Moreover, the Stroke Prevention by Aggressive Reduction in Cholesterol Levels (SPARCL) study has recently demonstrated that high-dose atorvastatin may also reduce the recurrence of stroke in patients with previous stroke or transitory ischemic attack.
authors.forename: José
authors.initials: J
authors.lastname: Tuñón
authors.forename: José Luis
authors.initials: JL
authors.lastname: Martín-Ventura
authors.forename: Luis Miguel
authors.initials: LM
authors.lastname: Blanco-Colio
authors.forename: Jesús
authors.initials: J
authors.lastname: Egido
mesh_terms: D002340:Carotid Artery Diseases / Q000188:drug therapy; D002986:Clinical Trials as Topic; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000627:therapeutic use*; D020521:Stroke / Q000188:drug therapy*; D013927:Thrombosis / Q000188:drug therapy
chemical_list: D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors