Structural basis of the activity of the microtubule-stabilizing agent epothilone a studied by NMR spectroscopy in solution.
Reese
Marcel
M
Abteilung für NMR-basierte Strukturbiologie, Max-Planck-Institut für Biophysikalische Chemie, Am Fassberg 11, 37077 Göttingen, Germany.
Sánchez-Pedregal
Víctor M
VM
Kubicek
Karel
K
Meiler
Jens
J
Blommers
Marcel J J
MJ
Griesinger
Christian
C
Carlomagno
Teresa
T
D000970:Antineoplastic Agents / Q000737:chemistry*; D034261:Epothilones / Q000737:chemistry*; D008274:Magnesium / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D008870:Microtubules / Q000737:chemistry / Q000187:drug effects* / Q000235:genetics; D008958:Models, Molecular; D012996:Solutions; D013329:Structure-Activity Relationship; D014404:Tubulin / Q000737:chemistry / Q000235:genetics
D000970:Antineoplastic Agents; D034261:Epothilones; D012996:Solutions; D014404:Tubulin; C093787:epothilone A; D008274:Magnesium