title: Case of skin necrosis due to arginine monohydrochloride extravasation.
abstract: A 10-month-old child presented with an ulcerated lesion on his right arm. The lesion was caused by arginine monohydrochloride extravasation during growth hormone testing, performed 2 months before. On physical examination, there was a 3 cm x 4 cm oval sore, with a thick fibrous base and turgid, violaceous, raised edges on the dorsal aspect of the child's right hand and wrist. Conservative management with local medications led to complete resolution within 2 months.
authors.affiliation: Department of Human and Hereditary Pathology, Dermatology Clinic, IRCCS Policlinico San Matteo, Italy. elisa_bassi@yahoo.it
authors.forename: Elisa
authors.initials: E
authors.lastname: Bassi
authors.forename: Davide
authors.initials: D
authors.lastname: Lonati
authors.forename: Roberta
authors.initials: R
authors.lastname: Pandolfi
authors.forename: Marco
authors.initials: M
authors.lastname: Gatti
authors.forename: Victoria M L
authors.initials: VM
authors.lastname: Jolliffe
authors.forename: Corrado
authors.initials: C
authors.lastname: Del Forno
mesh_terms: D001120:Arginine / Q000009:adverse effects*; D005119:Extravasation of Diagnostic and Therapeutic Materials / Q000150:complications* / Q000473:pathology; D006801:Humans; D007223:Infant; D008297:Male; D009336:Necrosis / Q000139:chemically induced; D012867:Skin / Q000473:pathology; D012883:Skin Ulcer / Q000139:chemically induced* / Q000473:pathology*; D014953:Wrist / Q000473:pathology
chemical_list: D001120:Arginine