[Electrophysiological characteristics of a population of mushroom body neurons in Apis mellifera L. honey bee under conditions of kynurenines deficit].
Neurophysiological characteristics of mushroom body neurons were examined by electrophysiological methods in mutants snow(laranja) and wild-type honey bees. Mutation snow(laranja) causes a drastic decrease in the activity of enzyme tryptophane oxygenase that results in deficiency of all kynurenines. It also modifies bioelectrical properties of neurons in the mushroom bodies. The duration of afterdepolarization in spikes recorded from calyx neurons and the amplitude of postsynaptic potentials in these neurons evoked by focal stimulation of antennal lobes were shown to be most dependent on the mutation and, consequently, on the content of endogenous kynurenines. A tendency to an increase in the frequency of spontaneous spikes was also observed. The effect of the mutation on neurophysiological characteristics under study was recessive, i.e. it was observed only in homozygous individuals.
Smirnov
V B
VB
Chesnokova
E G
EG
Lopatina
N G
NG
Voike
E
E
D000200:Action Potentials; D000818:Animals; D001516:Bees / Q000235:genetics / Q000502:physiology*; D007737:Kynurenine / Q000172:deficiency*; D008564:Membrane Potentials; D024521:Mushroom Bodies / Q000502:physiology*; D009154:Mutation; D009474:Neurons / Q000502:physiology*; D014366:Tryptophan Oxygenase / Q000235:genetics
D007737:Kynurenine; D014366:Tryptophan Oxygenase