title: [Antioxidant enzymes in skin experimental burn trauma].
abstract: The effect of experimental burn trauma (20%) on myeloperoxidase (MPO) and antioxidant enzymes (catalase, glutathione peroxidase (GPO), glutathione-S-transferase (GST)) was studied in unburned skin, epidermis (20 mm from the burned area) and the wound tissue of rats. The most common features were the increase of MPO on the 1st day and a delayed increase of GPO and GST after the 4th day. The additional operations (necrectomy) and lipopolysaccharide administration induced marked inflammatory reaction in skin and epidermis (evaluated by the increase in MPO and GPO/GST activities).
authors.forename: E V
authors.initials: EV
authors.lastname: Mokhal'chik
authors.forename: S M
authors.initials: SM
authors.lastname: Titkova
authors.forename: M V
authors.initials: MV
authors.lastname: Anurov
authors.forename: L Iu
authors.initials: LIu
authors.lastname: Pen'kov
authors.forename: L G
authors.initials: LG
authors.lastname: Korkina
mesh_terms: D000818:Animals; D000975:Antioxidants / Q000378:metabolism*; D002056:Burns / Q000201:enzymology* / Q000473:pathology; D004195:Disease Models, Animal; D004817:Epidermis / Q000201:enzymology* / Q000473:pathology; D015971:Gene Expression Regulation, Enzymologic / Q000187:drug effects; D007249:Inflammation / Q000201:enzymology / Q000473:pathology; D008070:Lipopolysaccharides / Q000494:pharmacology; D008297:Male; D010088:Oxidoreductases / Q000378:metabolism*; D051381:Rats; D017208:Rats, Wistar
chemical_list: D000975:Antioxidants; D008070:Lipopolysaccharides; D010088:Oxidoreductases