Solitary liver cysts in children: not always so simple.
OBJECTIVE
Liver cysts in children are uncommon. Many are simple and solitary and do not require intervention. However, this series demonstrates a broad range of potential pathologies, some of which are life-threatening.


METHODS
All children referred to our unit during an 8-year period (1998-2005) and found to have a solitary liver cyst were prospectively recorded. Clinical, radiologic, and pathologic features were analyzed. Children with an isolated extrahepatic choledochal cyst and polycystic disease were excluded.


RESULTS
Twenty-one children with a liver cyst were identified. Two had undergone unsuccessful surgical intervention before referral. There were 11 prenatally detected cysts. Median gestational age at detection was 22 weeks (19-35 weeks); only 1 was specifically characterized as a liver cyst prenatally. Six of these required surgery: 2 large simple cysts, 2 intrahepatic choledochal cysts, 1 giant complex biliary cyst causing respiratory distress, and 1 ciliated hepatic foregut cyst. Of the 5 cysts remaining under ultrasound surveillance, 4 decreased in size or resolved. In 10 children presenting between birth and 15.8 years, a liver cyst was diagnosed postnatally: 3 huge cystic mesenchymal hamartomas, 1 type V choledochal cyst, 1 hydatid cyst, and 5 simple cysts. Four of these required surgical resection. Simple cysts tended to be small and could be distinguished from other pathologies using a combination of imaging techniques (ultrasound, magnetic resonance imaging/magnetic resonance cholangiopancreatography [MRCP], radionuclide scan). Only 2 of 12 children with "simple" cysts required surgery for symptoms. However, a wide range of other cyst pathologies were found in 9 children, and although none was malignant, some were life-threatening and 7 required resection.


CONCLUSIONS
Simple solitary nonparasitic liver cysts rarely cause symptoms or require surgery, but the pediatric surgeon should be aware of the wide range of other types of liver cyst in children to ensure appropriate treatment.
Rogers
Tim N
TN
Children's Liver and GI Unit, Gledhow Wing, St. James's University Hospital, LS9 7TF Leeds, UK.
Woodley
Helen
H
Ramsden
William
W
Wyatt
Judy I
JI
Stringer
Mark D
MD
D000293:Adolescent; D017677:Age Distribution; D001707:Biopsy, Needle; D002648:Child; D002675:Child, Preschool; D015331:Cohort Studies; D003560:Cysts / Q000175:diagnosis* / Q000453:epidemiology* / Q000601:surgery; D005260:Female; D005315:Fetal Diseases / Q000175:diagnosis / Q000453:epidemiology / Q000601:surgery; D005500:Follow-Up Studies; D006498:Hepatectomy / Q000379:methods; D006801:Humans; D015994:Incidence; D007223:Infant; D010535:Laparoscopy / Q000379:methods; D008107:Liver Diseases / Q000175:diagnosis* / Q000453:epidemiology* / Q000601:surgery; D008279:Magnetic Resonance Imaging; D008297:Male; D011247:Pregnancy; D012189:Retrospective Studies; D018570:Risk Assessment; D017678:Sex Distribution; D016216:Ultrasonography, Prenatal; D006113:United Kingdom / Q000453:epidemiology