Ovulation in a postmenopausal woman.
OBJECTIVE
To report the first documented case of ovulation in a postmenopausal woman.


METHODS
Case study.


METHODS
University reproductive endocrinology and infertility clinic.


METHODS
A 57-year-old woman, who had been postmenopausal for 3 years and presented with breast tenderness and was found to have laboratory and ultrasound evidence of ovulation.


METHODS
Laboratory evaluation and transvaginal ultrasound.


METHODS
Ovulation in a postmenopausal woman.


RESULTS
Laboratory evaluations revealed estrogen and progesterone consistent with an ovulatory pattern. Ultrasound revealed a thickened endometrium and a corpus luteum, both of which resolved after menses.


CONCLUSIONS
This is the first report of ovulation in a postmenopausal woman. This observation opens the door to new questions about the sensitivity of the hypothalamic-pituitary-ovarian axis in menopause as well as about ovarian senescence.
Seungdamrong
Aimee
A
Department of Obstetrics, Gynecology, and Women's Health, New Jersey Medical School, University of Medicine and Dentistry New Jersey, Newark, NJ 07101, USA. seungdai@umdnj.edu
Weiss
Gerson
G
D004967:Estrogens / Q000097:blood; D005260:Female; D006801:Humans; D008875:Middle Aged; D010060:Ovulation / Q000097:blood*; D017698:Postmenopause / Q000097:blood*
D004967:Estrogens