HLA class I antigen and HLA-A, -B, and -C haplotype frequencies in Uruguayans.
HLA class I antigens were determined for 959 unrelated Uruguayans. The predominant HLA alleles were A2, Cw4, and B35, and the most frequently observed two-loci haplotypes were A2-B44 and B35-Cw4. The most frequent three-loci HLA haplotype was A2-Cw5-B44. We compared the Uruguayan sample with similar data from other populations.
Alvarez
Ines
I
Laboratorio de Inmunogenética e Histocompatibilidad, Instituto Nacional de Trasplante y Donación de Células, Tejidos y Organos (INDT), Hospital de Clinicas Manuel Quintela, Ave. Italia s/n Piso 4, CP 11600, Montevideo, Uruguay.
Bengochea
Milka
M
Toledo
Roberto
R
Carretto
Elena
E
Hidalgo
Pedro C
PC
D005787:Gene Frequency; D006680:HLA Antigens / Q000235:genetics*; D015234:HLA-A Antigens / Q000235:genetics; D015235:HLA-B Antigens / Q000235:genetics; D015236:HLA-C Antigens / Q000235:genetics; D006239:Haplotypes / Q000235:genetics*; D015395:Histocompatibility Antigens Class I / Q000235:genetics*; D006801:Humans; D014583:Uruguay
D006680:HLA Antigens; D015234:HLA-A Antigens; D015235:HLA-B Antigens; D015236:HLA-C Antigens; D015395:Histocompatibility Antigens Class I