Familial ectopia lentis with Axenfeld-Rieger anomaly.
Three siblings with ectopia lentis were examined for associated abnormalities. Case 1 had Axenfeld-Rieger anomaly and retinal detachment. Case 2 had Axenfeld-Rieger anomaly, ciliary staphyloma, and glaucoma. Case 3 had no associated ocular abnormality. The parents had normal eyesight. This is the first report of ectopia lentis associated with Axenfeld-Rieger anomaly. The mode of inheritance is likely autosomal recessive.
Singh
Deependra Vikram
DV
Vitreo-Retina Services, Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India.
Sharma
Yog Raj
YR
Azad
Raj Vardhan
RV
Pal
Nikhil
N
Gadagina
Shailesh
S
D000015:Abnormalities, Multiple; D000867:Anterior Chamber / Q000002:abnormalities*; D002648:Child; D002675:Child, Preschool; D004479:Ectopia Lentis / Q000175:diagnosis / Q000235:genetics*; D006801:Humans; D006849:Hydrocephalus / Q000175:diagnosis / Q000235:genetics*; D008297:Male; D035781:Siblings