title: Elevated high sensitivity CRP levels in patients with mitral stenosis and left atrial thrombus.
abstract: Stasis of blood in the left atrium (LA) due to mitral obstruction is the principal mechanism of LA thrombus formation in patients with mitral stenosis (MS). The purpose of this case-control study was to determine the additional contributions of abnormal homosysteine/folate/B12 levels, chronic inflammation and markers of a procoagulant state. We found that elevated hsCRP levels were associated with the presence of left atrial thrombus, independent of the influence of conventional parameters indicating the severity of MS and its consequences.
authors.forename: Ganesan
authors.initials: G
authors.lastname: Karthikeyan
authors.forename: Ajit
authors.initials: A
authors.lastname: Thachil
authors.forename: Sanjeev
authors.initials: S
authors.lastname: Sharma
authors.forename: M
authors.initials: M
authors.lastname: Kalaivani
authors.forename: Lakshmy
authors.initials: L
authors.lastname: Ramakrishnan
mesh_terms: D000328:Adult; D016279:Atrial Function, Left / Q000502:physiology*; D002097:C-Reactive Protein / Q000378:metabolism*; D006801:Humans; D008946:Mitral Valve Stenosis / Q000097:blood* / Q000150:complications / Q000175:diagnosis; D013927:Thrombosis / Q000097:blood* / Q000150:complications / Q000175:diagnosis
chemical_list: D002097:C-Reactive Protein