title: Low-grade malignant fibrosarcoma of the dental follicle of an unerupted third molar without clinical evidence of any follicular lesion.
abstract: BACKGROUND
  Sarcomas are rarely seen in the head and neck region. They make up less than 1% of all malignant head and neck tumours. Not only the location, size and systemic manifestation, but also the histological differentiation plays an essential role in establishing the best treatment. If resectable, surgical removal of the tumour with clear margins is the preferred method. Adjuvant chemo- and/or radiotherapy might be considered in the case of high-grade lesions or narrow surgical margins.
  
  
  METHODS
  This paper reports a 23-year-old female patient who underwent routine surgical removal of unerupted wisdom teeth without clinical evidence of any follicular lesion and was diagnosed with a low-grade malignant fibrosarcoma of the dental follicle of the lower left unerupted third molar.
  
  
  CONCLUSIONS
  This case report raises the question as to whether histological examination of all removed dental follicles should be carried out on a routine basis.
authors.affiliation: Department of Oral & Maxillofacial Surgery, University Hospital Tübingen, Tübingen, Germany. Christoph.Leitner@med.uni-tuebingen.de
authors.forename: Christoph
authors.initials: C
authors.lastname: Leitner
authors.forename: Jürgen
authors.initials: J
authors.lastname: Hoffmann
authors.forename: Stephan
authors.initials: S
authors.lastname: Kröber
authors.forename: Siegmar
authors.initials: S
authors.lastname: Reinert
mesh_terms: D000328:Adult; D003795:Dental Sac / Q000473:pathology*; D005260:Female; D005354:Fibrosarcoma / Q000175:diagnosis*; D006801:Humans; D008964:Molar, Third / Q000473:pathology*; D009367:Neoplasm Staging; D014076:Tooth Diseases / Q000175:diagnosis*; D014097:Tooth, Unerupted / Q000175:diagnosis*