title: [Foreign body reaction to materials implanted as biocompatible for internal fixation].
abstract: After implantation of resorbable materials for internal fixation, foreign body reactions are described in 0-47% of cases. Copolymers of poly-l-lactic acid (PLLA) and polyglycolic acid (PGA) seem to offer better biocompatibility than other materials. One of our patients had a midfacial fracture, which we fixed using a resorbable system based on PLLA-PGA (82%-18%); a foreign body reaction developed after 22 months. When resorbable materials are used it is essential to be aware specifically of the risk of foreign body reactions, especially when the facial area is involved. This risk must be discussed with the patient in some detail during the preoperative period.
authors.affiliation: Klinik für Hals-, Nasen- und Ohrenheilkunde, Kopf- und Halschirurgie der Martin-Luther-Universität Halle-Wittenberg, Magdeburger Strasse 12, 06112 Halle/Saale. alexander.thiele@medizin.uni-halle.de
authors.forename: Alexander
authors.initials: A
authors.lastname: Thiele
authors.forename: U
authors.initials: U
authors.lastname: Bilkenroth
authors.forename: M
authors.initials: M
authors.lastname: Bloching
authors.forename: St
authors.initials: S
authors.lastname: Knipping
mesh_terms: D000328:Adult; D001672:Biocompatible Materials / Q000009:adverse effects*; D005549:Foreign-Body Reaction / Q000175:diagnosis* / Q000209:etiology* / Q000517:prevention & control; D005593:Fracture Fixation, Internal / Q000009:adverse effects* / Q000295:instrumentation*; D006801:Humans; D008297:Male
chemical_list: D001672:Biocompatible Materials