title: [Graves' disease and autoimmune thrombocytopenic purpura: distinct outcomes of the two diseases].
abstract: The association of idiopathic thrombocytopenic purpura and Graves' disease is rare. Hence, little is known about the outcomes of these two diseases when associated. We report two cases of idiopathic thrombocytopenic purpura associated with Graves' disease, in which the two diseases had distinct outcomes. Thus, the hypothesis of cross-reaction between antithyroid antibodies and platelet epitopes, which has been proposed to explain the association, seems unlikely.
authors.affiliation: Service d'endocrinologie métabolisme, groupe hospitalier de la Pitié-Salpêtrière, APHP, 47-83, boulevard de l'Hôpital, 75013 Paris, France.
authors.forename: F
authors.initials: F
authors.lastname: Cohen Aubart
authors.forename: C
authors.initials: C
authors.lastname: Jublanc
authors.forename: E
authors.initials: E
authors.lastname: Bruckert
mesh_terms: D000328:Adult; D001323:Autoantibodies / Q000097:blood; D003429:Cross Reactions; D005260:Female; D006111:Graves Disease / Q000097:blood / Q000150:complications* / Q000628:therapy; D006801:Humans; D010976:Platelet Count; D016553:Purpura, Thrombocytopenic, Idiopathic / Q000097:blood / Q000150:complications* / Q000628:therapy; D013974:Thyroxine / Q000097:blood; D016896:Treatment Outcome
chemical_list: D001323:Autoantibodies; D013974:Thyroxine