title: Vitamin E and selenium supplementation reduces plasma cortisol and oxidative stress in dystocia-affected buffaloes.
abstract: The aim of the study was to evaluate oxidative stress around parturition in normally calved and dystocia-affected buffaloes and the clinical efficacy of vitamin E and selenium (Se) in reducing the effects in buffaloes suffering from dystocia. Plasma cortisol concentration, erythrocytic malondialdehyde (MDA) level and superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) activities were evaluated in dystocia-affected (supplemented (n = 8) and unsupplemented (n = 5) with vitamin E and Se) and normally calved (unsupplemented; n = 6) buffaloes. The decline in plasma cortisol concentration, MDA level and SOD activity was greater in the group of dystocia-affected buffaloes supplemented with vitamin E and Se (78.62 +/- 2.7%, 13.38 +/- 9.75% and 28.83 +/- 7.72%, respectively) than in the unsupplemented group (54.33 +/- 12.62%, 3.48 +/- 4.16% and 17.69 +/- 12.93%, respectively). These results suggests that supplementation with antioxidants like vitamin E and Se may be beneficial in reducing oxidative stress in dystocia-affected buffaloes in the immediate postpartum period.
authors.affiliation: Department of Animal Reproduction, Gynaecology and Obstetrics, Guru Angad Dev Veterinary and Animal Sciences University, Ludhiana, India. sathyavet@yahoo.com
authors.forename: A
authors.initials: A
authors.lastname: Sathya
authors.forename: S
authors.initials: S
authors.lastname: Prabhakar
authors.forename: S P S
authors.initials: SP
authors.lastname: Sangha
authors.forename: S P S
authors.initials: SP
authors.lastname: Ghuman
mesh_terms: D000818:Animals; D000975:Antioxidants / Q000008:administration & dosage*; D002020:Buffaloes / Q000502:physiology*; D019587:Dietary Supplements; D004420:Dystocia / Q000188:drug therapy / Q000662:veterinary*; D005260:Female; D005979:Glutathione Peroxidase / Q000097:blood; D006854:Hydrocortisone / Q000097:blood; D008315:Malondialdehyde / Q000097:blood; D018384:Oxidative Stress / Q000187:drug effects*; D011247:Pregnancy; D012643:Selenium / Q000008:administration & dosage*; D013482:Superoxide Dismutase / Q000097:blood; D013997:Time Factors; D014810:Vitamin E / Q000008:administration & dosage*
chemical_list: D000975:Antioxidants; D014810:Vitamin E; D008315:Malondialdehyde; D005979:Glutathione Peroxidase; D013482:Superoxide Dismutase; D012643:Selenium; D006854:Hydrocortisone