title: Characterization of a novel HLA-DRB1*04 allele (DRB1*0460) in the Italian population.
abstract: We report the identification of a novel HLA-DRB1*04, officially named DRB1*0460. It was detected during performing HLA-DRB1 high resolution typing by DNA sequencing-based method. The exon 2 nucleotide sequence of DRB1*0460 is identical to that of DRB1*040301 except at codon 63 (AGC-->AAC), changing the encoded serine to asparagine.
authors.affiliation: Dipartimento di Medicina Rigenerativa, Immunologia dei Trapianti di Organi e Tessuti, Fondazione IRCCS Ospedale Maggiore Policlinico, Mangiagalli, Regina Elena, Via Francesco Sforza 35, 20122 Milan, Italy.
authors.forename: S
authors.initials: S
authors.lastname: Frison
authors.forename: C
authors.initials: C
authors.lastname: Rinaldini
authors.forename: M
authors.initials: M
authors.lastname: Pagoda
authors.forename: C
authors.initials: C
authors.lastname: Brambilla
authors.forename: F
authors.initials: F
authors.lastname: Poli
mesh_terms: D000483:Alleles; D001483:Base Sequence; D006684:HLA-DR Antigens / Q000235:genetics*; D059811:HLA-DRB1 Chains; D006801:Humans; D007558:Italy; D008969:Molecular Sequence Data; D011153:Population / Q000235:genetics; D044465:White People / Q000235:genetics
chemical_list: D006684:HLA-DR Antigens; D059811:HLA-DRB1 Chains; C519203:HLA-DRB1*04:60 antigen