title: Isolated pulmonary Langerhans cell histiocytosis in a 17-year-old male.
abstract: We report a case of a previously healthy 17-year-old male with a history of cigarette smoking, who presented with acute development of respiratory distress. Computed tomography demonstrated cystic pulmonary changes. A lung biopsy confirmed Langerhans cell histiocytosis (LCH). The definitive diagnosis was isolated pulmonary LCH, a disorder that is infrequently found in adults, and rarely in children. We know of only one other case of a previously healthy adolescent cigarette smoker who developed isolated pulmonary LCH. The etiology of pulmonary LCH is unknown, but smoking has been considered as a risk factor.
authors.affiliation: Departments of Pediatrics, School of Medicine, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA. Edna.Adams@ttuhsc.edu
authors.forename: Edna P
authors.initials: EP
authors.lastname: Adams
authors.forename: David
authors.initials: D
authors.lastname: Sauceda
authors.forename: Jeffrey
authors.initials: J
authors.lastname: Oliver
authors.forename: Anthony
authors.initials: A
authors.lastname: Cecalupo
mesh_terms: D000293:Adolescent; D001706:Biopsy; D006646:Histiocytosis, Langerhans-Cell / Q000209:etiology* / Q000473:pathology* / Q000503:physiopathology; D006801:Humans; D008168:Lung / Q000473:pathology; D008297:Male; D012129:Respiratory Function Tests; D012907:Smoking / Q000009:adverse effects*; D014057:Tomography, X-Ray Computed