title: A direct electrochemical biosensing platform constructed by incorporating carbon nanotubes and gold nanoparticles onto redox poly(thionine) film.
abstract: A direct electrochemical biosensing platform has been fabricated by covalent incorporation of carbon nanotubes (CNT) and gold nanoparticles (GNP) onto the poly(thionine) (PTH) film deposited by electropolymerization. With the synergic effects of the composite nanomaterials together with the excellent mediating redox polymer, the proposed platform could allow for faster electron transfer and higher enzyme immobilization efficiency than the platforms designed by using CNT or GNP alone. Comparison studies indicated that the as-developed H(2)O(2) sensor could show greatly improved performances of amperometric responses.
authors.affiliation: State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha, PR China.
authors.forename: Hui
authors.initials: H
authors.lastname: Feng
authors.forename: Hua
authors.initials: H
authors.lastname: Wang
authors.forename: Yun
authors.initials: Y
authors.lastname: Zhang
authors.forename: Bani
authors.initials: B
authors.lastname: Yan
authors.forename: Guoli
authors.initials: G
authors.lastname: Shen
authors.forename: Ruqin
authors.initials: R
authors.lastname: Yu
mesh_terms: D015374:Biosensing Techniques / Q000295:instrumentation / Q000379:methods*; D004563:Electrochemistry; D004566:Electrodes; D006046:Gold / Q000737:chemistry*; D006861:Hydrogen Peroxide / Q000032:analysis; D053758:Nanoparticles; D037742:Nanotubes, Carbon / Q000737:chemistry*; D010084:Oxidation-Reduction; D010640:Phenothiazines / Q000737:chemistry*; D011108:Polymers / Q000737:chemistry*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity
chemical_list: D037742:Nanotubes, Carbon; D010640:Phenothiazines; D011108:Polymers; D006046:Gold; D006861:Hydrogen Peroxide; C009469:thionine