[Prognostic possibilities of immunogenetic markers application in adhesive disease of abdominal cavity].
Modern knowledge concerning adhesive disease of abdominal cavity is imperfect, that's why it is necessary to discover new and effective methods of investigation of the disease to improve prophylactic and treatment measures. There was studied up the distribution of the HLA system antigens in adhesive disease, markers of predisposition to the disease occurrence were revealed. The HLA typing results in 52 patients of Georgian nationality, suffering adhesive disease of abdominal cavity, are presented. Trustworthy increase of frequency of the HLA antigens Al, B15, B21 revealing was noted in patients in comparison with such in control group. According to the relative risk criterion, maximal possibility of the adhesive illness occurrence was connected with HLA-B15 antigen. It may be concluded that in Georgian population antigen HLA-B15 constitutes a genetic marker of the adhesive illness occurrence.
Marshava
O M
OM
Tokhadze
L T
LT
Lagvilava
L D
LD
Khutsishvili
K R
KR
D015415:Biomarkers / Q000032:analysis; D005260:Female; D015235:HLA-B Antigens / Q000032:analysis* / Q000276:immunology; D059910:HLA-B15 Antigen; D006801:Humans; D008297:Male; D010532:Peritoneal Diseases / Q000276:immunology* / Q000601:surgery; D011237:Predictive Value of Tests; D000267:Tissue Adhesions / Q000276:immunology / Q000601:surgery
D015415:Biomarkers; D015235:HLA-B Antigens; D059910:HLA-B15 Antigen