title: Materials characterization of explanted polypropylene hernia meshes.
abstract: Hernia repair with prosthetic mesh significantly decreases the rate of recurrence compared with traditional, primary suture repair by reducing the tension on the edges of the wound. However, there are several complications associated with the use of mesh that may be due to the chronic inflammatory reaction to the mesh or a loss of compliance after degradation of the material. Mesh contraction and migration can also occur, sometimes resulting in a recurrent hernia. Based on the chemical structure of the polypropylene mesh material and the physiological conditions to which it is subjected, it is possible that oxidation is responsible for these changes in material properties. Oxidation would result in surface cracking, decreased melting temperature, loss of mass, and reduced compliance of the material. The objective of this study was to identify physiochemical changes in the surface and bulk properties of explanted polypropylene hernia meshes compared to pristine polypropylene mesh materials. Several characterization techniques were utilized, including scanning electron microscopy, differential scanning calorimetry, thermogravimetric analysis, and compliance testing. Overall, the results supported our hypothesis that oxidation is involved with the degradation of polypropylene hernia mesh materials.
authors.affiliation: Department of Biological Engineering, University of Missouri-Columbia, Columbia, Missouri, USA.
authors.forename: C R
authors.initials: CR
authors.lastname: Costello
authors.forename: S L
authors.initials: SL
authors.lastname: Bachman
authors.forename: B J
authors.initials: BJ
authors.lastname: Ramshaw
authors.forename: S A
authors.initials: SA
authors.lastname: Grant
mesh_terms: D001672:Biocompatible Materials / Q000737:chemistry / Q000378:metabolism; D046449:Hernia, Abdominal / Q000601:surgery; D006801:Humans; D008422:Materials Testing; D010084:Oxidation-Reduction; D011126:Polypropylenes / Q000737:chemistry / Q000378:metabolism; D019736:Prostheses and Implants; D011474:Prosthesis Design; D013314:Stress, Mechanical; D013499:Surface Properties; D013526:Surgical Mesh
chemical_list: D001672:Biocompatible Materials; D011126:Polypropylenes