Selective monocyclization of epoxy terpenoids promoted by zeolite NaY. A short biomimetic synthesis of elegansidiol and farnesiferols B-D.
Epoxy terpenes cyclize readily, by confinement within zeolite NaY, to form exomethylenic cyclohexanols as the major products. The selective monocyclization of 10,11-epoxyfarnesyl acetate within NaY provides a short and efficient biomimetic route to (+/-)-elengasidiol and (+/-)-farnesiferols B-D. [reaction: see text].
Tsangarakis
Constantinos
C
Department of Chemistry, University of Crete, Voutes 71003 Iraklion, Greece.
Arkoudis
Elias
E
Raptis
Christos
C
Stratakis
Manolis
M