title: Simulating leukocyte-venule interactions--a novel agent-oriented approach.
abstract: Leukocyte recruitment into sites of inflammation involves a complex cascade of molecular interactions between the leukocyte and the endothelial cells of the inflamed venule. This report proposes a novel agent-oriented approach for simulating leukocyte-venule interactions during inflammation. We focus on modeling and simulating the initial steps of rolling, activation, and firm adhesion of neutrophils on TNF-alpha-treated mouse cremaster muscle venules.
authors.affiliation: California University, San Francisco, CA, USA.
authors.forename: J
authors.initials: J
authors.lastname: Tang
authors.forename: C A
authors.initials: CA
authors.lastname: Hunt
authors.forename: J
authors.initials: J
authors.lastname: Mellein
authors.forename: K
authors.initials: K
authors.lastname: Ley