title: Should subgroup analysis of randomized clinical trials have a direct impact on clinical practice?
authors.forename: Emilio
authors.initials: E
authors.lastname: Bria
authors.forename: Massimo
authors.initials: M
authors.lastname: Di Maio
authors.forename: Federica
authors.initials: F
authors.lastname: Cuppone
authors.forename: Cecilia
authors.initials: C
authors.lastname: Nisticò
authors.forename: Francesco
authors.initials: F
authors.lastname: Cognetti
authors.forename: Diana
authors.initials: D
authors.lastname: Giannarelli
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D015179:Colorectal Neoplasms / Q000188:drug therapy* / Q000401:mortality; D003627:Data Interpretation, Statistical; D005260:Female; D006801:Humans; D008297:Male; D017410:Practice Guidelines as Topic; D016032:Randomized Controlled Trials as Topic / Q000379:methods*; D012107:Research Design; D012737:Sex Factors; D016019:Survival Analysis; D016896:Treatment Outcome