Differentiation of Parkinson's disease and progressive supranuclear palsy with magnetic resonance imaging: the first Brazilian experience.
BACKGROUND
The objective of this study is to differentiate PSP from Parkinson's disease through magnetic resonance imaging.


METHODS
We included 14 consecutive patients with PD (9) or PSP (5). These measures included the third ventricle, midbrain diameter, quadrigeminal plate, brainstem volumetry, and interpeduncular angle.


RESULTS
Patients with PSP presented enlargement of third ventricle (100% vs. 33%), lower midbrain diameter (mean 13.2 +/- 1.7 mm vs. 16.5 +/- 1.7 mm) and thinning of the quadrigeminal plate (mean 2.7 +/- 0.3 mm vs. 3.6 +/- 0.3 mm) in comparison with PD.


CONCLUSIONS
Characteristic findings on MRI may help to differentiate PD from PSP.
Barsottini
Orlando G P
OG
Department of Neurology, Universidade Federal de São Paulo, Rua Cabedelo, 265 São Paulo, SP, Brazil. orlandobarsottini@gmail.com
Ferraz
Henrique B
HB
Maia
Antonio C M
AC
Silva
Carlos J
CJ
Rocha
Antonio J
AJ
D000368:Aged; D001921:Brain / Q000473:pathology*; D001938:Brazil / Q000453:epidemiology; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D010300:Parkinson Disease / Q000175:diagnosis*; D013494:Supranuclear Palsy, Progressive / Q000175:diagnosis*