The "all-or-none" law in skeletal muscle and nerve fibres.
In 1905 the Cambridge physiologist Keith Lucas extended the "all-or-none" principle (introduced by H. P. Bowditch for the cardiac tissue) to skeletal muscle and nerve fibres. Nevertheless, in a short time it was clear that nerve fibres obey this law, but also that frequency of discharge is another relevant factor in the nervous conduction.
Pareti
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Dipartimento di Filosofia, University of Turin.
D000818:Animals; D005858:Germany; D049672:History, 19th Century; D049673:History, 20th Century; D006801:Humans; D023421:Models, Animal; D009046:Motor Neurons / Q000502:physiology*; D009119:Muscle Contraction / Q000502:physiology; D018482:Muscle, Skeletal / Q000294:innervation* / Q000502:physiology*; D009431:Neural Conduction / Q000502:physiology; D009469:Neuromuscular Junction / Q000502:physiology; D009482:Neurophysiology / Q000266:history*; D010525:Peripheral Nerves / Q000502:physiology*; D006113:United Kingdom