title: Cytochromes P460 and c'-beta; a new family of high-spin cytochromes c.
abstract: Cytochromes-P460 of Nitrosomonas europaea and Methylococcus capsulatus (Bath), and the cytochrome c' of M. capsulatus, believed to be involved in binding or transformation of N-oxides, are shown to represent an evolutionarily related new family of monoheme, approximately 17kDa, cytochromes c found in the genomes of diverse Proteobacteria. All members of this family have a predicted secondary structure predominantly of beta-sheets in contrast to the predominantly alpha-helical cytochromes c' found in photoheterotrophic and denitrifying Proteobacteria.
authors.affiliation: Department of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota, St. Paul, MN, USA.
authors.forename: Bradley O
authors.initials: BO
authors.lastname: Elmore
authors.forename: David J
authors.initials: DJ
authors.lastname: Bergmann
authors.forename: Martin G
authors.initials: MG
authors.lastname: Klotz
authors.forename: Alan B
authors.initials: AB
authors.lastname: Hooper
mesh_terms: D000595:Amino Acid Sequence; D001426:Bacterial Proteins / Q000737:chemistry / Q000145:classification / Q000235:genetics / Q000378:metabolism; D002942:Circular Dichroism; D003580:Cytochromes / Q000737:chemistry* / Q000145:classification / Q000235:genetics / Q000378:metabolism*; D045304:Cytochromes c / Q000737:chemistry* / Q000145:classification / Q000235:genetics / Q000378:metabolism*; D045305:Cytochromes c' / Q000737:chemistry* / Q000145:classification / Q000235:genetics / Q000378:metabolism*; D019143:Evolution, Molecular; D020619:Methylococcus capsulatus / Q000235:genetics / Q000378:metabolism; D043370:Nitrosomonas europaea / Q000235:genetics / Q000378:metabolism; D010802:Phylogeny; D017433:Protein Structure, Secondary; D017386:Sequence Homology, Amino Acid
chemical_list: D001426:Bacterial Proteins; D003580:Cytochromes; D045305:Cytochromes c'; C080650:cytochrome P-460; D045304:Cytochromes c