[Chemical constituents from water extract of Radix isatidis].
OBJECTIVE
To study the chemical constituents from water extract of Radix isatidis. (Isatis indigotica Fort. ).


METHODS
The water extract was underwent absorption by D101 macroporous resin, the portion eluted by ethanol of different concentrations was isolated and purified on silica gel column repeatedly. The obtained compounds were identified and structurally elucidated by their physico-chemical properties and spectral analysis.


RESULTS
Five compounds were isolated from water extract of Radix isatidis, and were partly identified separately: 3-[2'-(5'-hydroxymethyl) furyl] -1 (2H) -isoquinolinone-7-O-beta-D-glucoside (I), lariciresinol-4,4'-di-O-beta-D-glucopyranoside (II), lariciresinol-4-O-beta-D-glucopyranoside (III), 2-hydroxy-1, 4-benzenedicarboxylic acid (IV), mannitol (V).


CONCLUSIONS
Compound I is a new compound and compounds IV and V were isolated from the plant for the first time.
He
Li-Wei
LW
Nanjing University of Traditional Chinese Medicine, Nanjing 210046, China.
Li
Xiang
X
Chen
Jian-Wei
JW
Sun
Dong-Dong
DD
Jü
Wen-Zheng
WZ
Wang
Kang-Cai
KC
D031219:Isatis / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D010936:Plant Extracts / Q000032:analysis*
D010936:Plant Extracts