First protection of a wide-rim tetraamino calix[4]arene in opposite positions.
The importance of tetraamino calix[4]arenes as starting materials is distinctly increased by the first versatile protective group for opposite amino functions. Reaction with trityl chloride leads to the 1,3-dialkylated derivative easily isolated in 34% yield; after a first acylation of the remaining amino groups, the trityl residues can be removed by TFA to introduce a second acyl group. [reaction: see text]
Rudzevich
Yuliya
Y
Abteilung Lehramt Chemie, Fachbereich Chemie, Pharmazie und Geowissenschaften, Johannes Gutenberg-Universität Mainz, Duesbergweg 10-14, D-55099 Mainz, Germany. rudzevic@uni-mainz.de
Rudzevich
Valentyn
V
Schollmeyer
Dieter
D
Böhmer
Volker
V