title: Probing the substrate specificity of the catalytically self-sufficient cytochrome P450 RhF from a Rhodococcus sp.
abstract: Analysis of the substrate specificity of the self-sufficient cytochrome P450 RhF revealed that the enzyme tends to catalyse the dealkylation of substituted alkyl-aryl ethers with shorter alkyl moieties more readily than equivalent compounds with longer alkyl groups.
authors.affiliation: School of Chemistry, University of Edinburgh, The King's Buildings, West Mains Road, Edinburgh, UK.
authors.forename: Ayhan
authors.initials: A
authors.lastname: Celik
authors.forename: Gareth A
authors.initials: GA
authors.lastname: Roberts
authors.forename: John H
authors.initials: JH
authors.lastname: White
authors.forename: Stephen K
authors.initials: SK
authors.lastname: Chapman
authors.forename: Nicholas J
authors.initials: NJ
authors.lastname: Turner
authors.forename: Sabine L
authors.initials: SL
authors.lastname: Flitsch
mesh_terms: D000478:Alkylation; D002384:Catalysis; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism*; D004987:Ethers / Q000378:metabolism; D012240:Rhodococcus; D013379:Substrate Specificity
chemical_list: D004987:Ethers; D003577:Cytochrome P-450 Enzyme System