A mild synthesis of vinyl halides and gem-dihalides using triphenyl phosphite-halogen-based reagents.
A new application of (PhO)3P-halogen-based reagents to the synthesis of vinyl halides and gem-dihalides is described. Vinyl halides were prepared in good to excellent yields from enolizable ketones, whereas aldehydes afforded the corresponding gem-dihalides. The halogenation proceeded smoothly under mild conditions.
Spaggiari
Alberto
A
Dipartimento di Chimica, Università di Modena e Reggio Emilia, via Campi 183, 41100 Modena, Italy.
Vaccari
Daniele
D
Davoli
Paolo
P
Torre
Giovanni
G
Prati
Fabio
F