[Smoking influence on cadmium, lead, selenium and zinc level in placenta, cord blood and maternal blood of women at delivery from Gdansk region].
Cadmium, lead, selenium and zinc levels were determined in placenta, maternal blood and cord blood of 53 women at delivery from Gdansk region. Non-smokers [NS], passive smokers [PS] and smokers [S] were identified by the questionnaire. Our results suggest that there is no smoking impact on the levels of determined elements in placenta. Smoking women have higher Cd and Pb blood levels than mothers who never smoked (p < 0.01). Selenium levels in maternal and cord blood were higher in non-smoking group than in smokers (maternal blood NS vs S p < 0.01; cord blood NS vs S p < 0.001), but there is no smoking impact on the zinc levels in the study tissues. We also investigated the negative influence of tobacco smoke exposure on the distribution of the micro-elements in the feto-placental unit and that the ratio of Zn/Cd and Se/ Pb is higher in all tissues of non-smoking than smoking women.
Szyszko
Małgorzata
M
Katedra i Zakład Toksykologii, Akademia Medyczna w Gdańsk. mszyszko@amg.gda.pl
Czarnowski
Wojciech
W
D000293:Adolescent; D000328:Adult; D001034:Apgar Score; D002104:Cadmium / Q000032:analysis*; D003367:Cotinine / Q000097:blood; D004784:Environmental Monitoring; D005260:Female; D005312:Fetal Blood / Q000737:chemistry*; D006801:Humans; D007231:Infant, Newborn; D007854:Lead / Q000032:analysis*; D018811:Maternal Exposure; D008431:Maternal-Fetal Exchange; D010920:Placenta / Q000737:chemistry*; D011044:Poland; D011247:Pregnancy; D011248:Pregnancy Complications / Q000097:blood*; D012643:Selenium / Q000032:analysis*; D012907:Smoking / Q000097:blood*; D015032:Zinc / Q000032:analysis
D002104:Cadmium; D007854:Lead; D012643:Selenium; D015032:Zinc; D003367:Cotinine