[Dependence of erythrocyte electrophoretic mobility of human and rat blood on cell volume in health and pathology].
To study correlations between electrophoretic mobility of erythrocytes and their volume, we compared blood samples from intact rats, animals exposed to extreme impacts, healthy humans and cancer patients. In rats, the above erythrocytes indices were closely related polynomially--deviations of the cell volume in both directions from physiological values are accompanied with a fall of mean cell mobility in electric field. In healthy subjects electrophoretic mobility of erythrocytes and their volume vary independently, in cancer these parameters are related curvilinearly.
Matiushichev
V B
VB
Shamratova
V G
VG
D000328:Adult; D000818:Animals; D048429:Cell Size; D004586:Electrophoresis; D004911:Erythrocyte Volume; D004912:Erythrocytes / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D051381:Rats; D011919:Rats, Inbred Strains; D013274:Stomach Neoplasms / Q000097:blood* / Q000503:physiopathology*