title: Histological diagnosis of spinal chondrosarcoma by endobronchial ultrasound-guided transbronchial needle aspiration.
abstract: Rare neoplastic diseases including sarcomas can occur in the middle mediastinum. Obtaining a histological specimen is crucial for diagnosis and for establishing a treatment plan. Our research group has recently reported a minimal invasive method of tissue sampling of the mediastinum using direct real-time endobronchial ultrasound-guided transbronchial needle aspiration. By the use of this new modality, histological cores can be obtained for pathological diagnosis that can be used for immunohistochemistry as well as genetic analysis. A very rare case of spinal chondrosarcoma due to hereditary multiple exostoses successfully diagnosed by endobronchial ultrasound-guided transbronchial needle aspiration and by immunohistochemistry with genetic analysis is reported.
authors.affiliation: Department of Thoracic Surgery, Graduate School of Medicine, Chiba University, Chiba, Japan.
authors.forename: Takahiro
authors.initials: T
authors.lastname: Nakajima
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Yasufuku
authors.forename: Makoto
authors.initials: M
authors.lastname: Suzuki
authors.forename: Yasuo
authors.initials: Y
authors.lastname: Sekine
authors.forename: Kiyoshi
authors.initials: K
authors.lastname: Shibuya
authors.forename: Kenzo
authors.initials: K
authors.lastname: Hiroshima
authors.forename: Takehiko
authors.initials: T
authors.lastname: Fujisawa
mesh_terms: D001707:Biopsy, Needle / Q000379:methods; D001859:Bone Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D001999:Bronchoscopy; D002813:Chondrosarcoma / Q000000981:diagnostic imaging / Q000473:pathology*; D003937:Diagnosis, Differential; D019160:Endosonography; D006801:Humans; D008297:Male; D008875:Middle Aged; D013904:Thoracic Vertebrae