[Prevalence and characteristics of metabolic syndrome among HIV-infected patients from a Mediterranean cohort].
OBJECTIVE
The objective of this study was to estimate the prevalence and characteristics of the metabolic syndrome in patients with HIV infection from a Mediterranean cohort.


METHODS
Cross-sectional study performed in consecutive HIV-infected patients attended in an outpatient's HIV clinic at the Mediterranean coast of Spain. Metabolic syndrome was defined according to the International Diabetes Federation (IDF) new diagnostic criteria.


RESULTS
We analyzed data from 210 patients, 160 (76.19%) of whom were undergoing antiretroviral therapy. Most of them (47.14%) were receiving combinations of non-nucleoside reverse transcriptase inhibitors, whereas 22.8% of them were being treated with protease inhibitors. The prevalence of metabolic syndrome was 11.42% (95% CI, 6.89%-15.97%). Hypertriglyceridemia was present in 68 (32.38%) patients and low HDL-cholesterol levels were observed in 98 (46.6%). Body mass index [OR = 1.40; 95% CI, 1.21-1.62; p = 0.001] and age [OR = 1.062; 95% CI, 1.018-1.108; p = 0.001] were independently associated with metabolic syndrome.


CONCLUSIONS
Patients with HIV infection from this Mediterranean cohort had a low prevalence of metabolic syndrome. Body mass index and age are the main factors associated with this syndrome.
Bernal
Enrique
E
Unidad de Enfermedades Infecciosas, Hospital General Universitario de Elche, Elche, Alicante, España. enrbernal@yahoo.es
Masiá
Mar
M
Padilla
Sergio
S
Martín-Hidalgo
Alberto
A
Gutiérrez
Félix
F
D000328:Adult; D000368:Aged; D005260:Female; D015658:HIV Infections / Q000150:complications*; D006801:Humans; D008297:Male; D019083:Mediterranean Region; D024821:Metabolic Syndrome / Q000150:complications / Q000175:diagnosis* / Q000453:epidemiology*; D008875:Middle Aged; D015995:Prevalence; D013030:Spain