Carbamazepine poisoning managed with haemodialysis and haemoperfusion in three adolescents.
Carbamazepine is a widely used antiepileptic agent. Accidental or suicidal overdose in children is not uncommon. Acute toxicity is associated with seizures, coma, arrhythmias and death in severe cases. Here we report three adolescents with carbamzepine overdose, two managed with standard low-flux haemodialysis and one with charcoal haemoperfusion. Our report emphasizes that haemodialysis might be a cheaper and easier alternative for carbamazepine overdose in milder cases, with fewer side-effects than haemoperfusion.
Bek
Kenan
K
Department of Paediatric Nephrology, Faculty of Medicine, Ondokuz Mayis University, Samsun, Turkey. kenanbek2000@yahoo.com
Koçak
Sule
S
Ozkaya
Ozan
O
Yilmaz
Yunus
Y
Aydin
Omer Faruk
OF
Taşdöven
Cigdem Sag
CS
D000293:Adolescent; D000927:Anticonvulsants / Q000506:poisoning*; D002220:Carbamazepine / Q000506:poisoning*; D002606:Charcoal / Q000008:administration & dosage*; D002648:Child; D062787:Drug Overdose / Q000503:physiopathology / Q000628:therapy*; D005260:Female; D006464:Hemoperfusion; D006801:Humans; D007902:Length of Stay; D008297:Male; D006435:Renal Dialysis; D016896:Treatment Outcome
D000927:Anticonvulsants; D002606:Charcoal; D002220:Carbamazepine