title: [Cardiovascular risk profile of uncontrolled hypertensive patients. The Control-Project study].
abstract: OBJECTIVE
  To assess absolute cardiovascular risk and co-morbidities in uncontrolled hypertensive patients (blood pressure [BP]>or=140/90 mmHg or>or=130/80 mmHg in diabetics) attending Primary Care Physicians in Spain, and to determine the attitudes of these physicians towards this problem.
  
  
  METHODS
  Cross-sectional, multicenter study involving 356 general practitioners around Spain. Absolute cardiovascular risk was assessed according to ESH-ESC 2003 Guidelines in a sample of 1,710 patients.
  
  
  RESULTS
  Two hundred ninety seven patients were excluded by several reasons and a total of 1,413 hypertensive patients were valuable (mean age: 65.3+/-11.4 years; 56.7% women). Normal BP values (<140/90 mmHg) were exhibited by 0.2%, high-normal BP (120-139/80-89 mmHg) were exhibited by 2.8%, grade 1 hypertension (140-159/90-99 mmHg) by 49.9%, grade 2 hypertension (160-179/100-109 mmHg) by 39.3%, and grade 3 hypertension (>or=180/110 mmHg) by 7.9%. Associated cardiovascular risk factors were observed in 96.0% of patients (95% CI=94.7-97.2%), target organ damage in 34.5% (95% CI=31.6-36.5%), and cardiovascular clinical disease in 36.0% (95% CI=33.5-38.5%). According to ESH-ESC 2003 Guidelines 34.0% (CI=31.5-38.2%) were at very-high risk; 29.4% (95% CI=26.4-32.8%) at high risk; 30.4% (95% CI=27.2-33.7%) at moderate risk and 5.4% (95% CI=3.9-7.2%) at low risk of cardiovascular disease. Despite the high absolute risk, physicians did not do any therapeutic change in 30.4% (95% CI=28.2-33.5%) of uncontrolled hypertensive patients. Most of them (64.26%) considered that bad compliance to life style changes was the reason for inadequate BP control. The most frequent measure introduced was the association of additional drugs.
  
  
  CONCLUSIONS
  Absolute cardiovascular risk in uncontrolled hypertensive patients attending Primary Care Physicians in Spain is very relevant. Sixty-five percent of these patients are at high or very high risk with a high prevalence of target organ damage or associated cardiovascular clinical disease. Therapeutic attitudes towards these patients are still very conservative although they are improving compared with previous studies.
authors.affiliation: Centro de Salud la Orden, Huelva, Spain. emarquezc@papps.org
authors.forename: Emilio
authors.initials: E
authors.lastname: Márquez-Contreras
authors.forename: Antonio
authors.initials: A
authors.lastname: Coca
authors.forename: Mariano
authors.initials: M
authors.lastname: de la Figuera von Wichmann
authors.forename: Juan Antonio
authors.initials: JA
authors.lastname: Divisón
authors.forename: José Luis
authors.initials: JL
authors.lastname: Llisterri
authors.forename: Javier
authors.initials: J
authors.lastname: Sobrino
authors.forename: Claudia
authors.initials: C
authors.lastname: Filozof
authors.forename: Miguel Angel
authors.initials: MA
authors.lastname: Sánchez-Zamorano
authors.forename: Lilian
authors.initials: L
authors.lastname: Grigorian Shamagian
mesh_terms: D000368:Aged; D002318:Cardiovascular Diseases / Q000453:epidemiology* / Q000209:etiology*; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications* / Q000628:therapy; D008297:Male; D018570:Risk Assessment; D012307:Risk Factors