title: Isolated congenital diaphragmatic hernia in the third trimester: a case report and literature review.
abstract: OBJECTIVE
  To report a rare congenital anomaly, a right diaphragmatic hernia, in a near-term baby.
  
  
  METHODS
  A 40-year-old female, gravida 3, para 2, had undergone regular prenatal care in our department since the early second trimester. She underwent amniocentesis at 16 weeks of gestation. The result showed normal 46,XY. Fetal growth was appropriate throughout the pregnancy. A small heart with marked left-side deviation was noted in the third trimester. The heart rate was less than 25% of normal. A homogenous mass with centralized vessels was noted in the fetus's right chest. The baby showed respiratory distress immediately after delivery. Imaging studies after birth proved there was a right diaphragmatic hernia with severe pulmonary hypertension and poor lung function.
  
  
  CONCLUSIONS
  Right congenital diaphragmatic hernia is rare. A prenatal diagnosis is difficult to make in the second trimester. Prognosis is greatly influenced by the associated abnormalities.
authors.affiliation: Department of Obstetrics and Gynecology, Chi Mei Hospital, Liou-Ying, Tainan, Taiwan. chia007@iris.seed.net.tw
authors.forename: Chun-Chieh
authors.initials: CC
authors.lastname: Chia
authors.forename: Soon-Cen
authors.initials: SC
authors.lastname: Huang
authors.forename: Chun-Hui
authors.initials: CH
authors.lastname: Chang
mesh_terms: D000328:Adult; D036861:Delivery, Obstetric; D005260:Female; D005315:Fetal Diseases / Q000000981:diagnostic imaging* / Q000503:physiopathology; D006340:Heart Rate, Fetal; D006548:Hernia, Diaphragmatic / Q000150:complications / Q000196:embryology*; D065630:Hernias, Diaphragmatic, Congenital; D006801:Humans; D006976:Hypertension, Pulmonary / Q000150:complications / Q000503:physiopathology; D007231:Infant, Newborn; D008168:Lung / Q000503:physiopathology; D011247:Pregnancy; D011263:Pregnancy Trimester, Third; D012127:Respiratory Distress Syndrome, Newborn / Q000209:etiology / Q000503:physiopathology; D016216:Ultrasonography, Prenatal