title: A challenging insight on the structural unit 1 of molluscan Rapana venosa hemocyanin.
abstract: Hemocyanins of mollusks are high molecular mass glycoproteins with a complex quaternary structure which still remains to be defined in detail for most of its species as far as number, spatial distribution and interactions of their structural units is concerned. In the present study, we isolated the functional units of the structural subunit RvH1 of Rapana venosa hemocyanin, combining enzymatic and non-enzymatic methods. Our results suggest that Hc's carbohydrate moieties play a basic role in the organization of the structural units, resulting from post-translational polymerization of the 50 kDa functional units and involving sugar moieties that link between them.
authors.affiliation: Institute of Organic Chemistry, Bulgarian Academy of Sciences, G. Bonchev 9, Sofia 1113, Bulgaria. pda54@yahoo.com
authors.forename: Pavlina
authors.initials: P
authors.lastname: Dolashka-Angelova
authors.forename: Stefan
authors.initials: S
authors.lastname: Stevanovic
authors.forename: Alexandar
authors.initials: A
authors.lastname: Dolashki
authors.forename: Bart
authors.initials: B
authors.lastname: Devreese
authors.forename: Bonka
authors.initials: B
authors.lastname: Tzvetkova
authors.forename: Wolfgang
authors.initials: W
authors.lastname: Voelter
authors.forename: Jozef
authors.initials: J
authors.lastname: Van Beeumen
authors.forename: Benedetto
authors.initials: B
authors.lastname: Salvato
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D006433:Hemocyanins / Q000737:chemistry*; D006801:Humans; D008969:Molecular Sequence Data; D008970:Molecular Weight; D008974:Mollusca / Q000201:enzymology*; D013329:Structure-Activity Relationship; D014508:Urea / Q000737:chemistry*
chemical_list: D014508:Urea; D006433:Hemocyanins