A wavelet-chaos methodology for analysis of EEGs and EEG subbands to detect seizure and epilepsy.
A wavelet-chaos methodology is presented for analysis of EEGs and delta, theta, alpha, beta, and gamma subbands of EEGs for detection of seizure and epilepsy. The nonlinear dynamics of the original EEGs are quantified in the form of the correlation dimension (CD, representing system complexity) and the largest Lyapunov exponent (LLE, representing system chaoticity). The new wavelet-based methodology isolates the changes in CD and LLE in specific subbands of the EEG. The methodology is applied to three different groups of EEG signals: 1) healthy subjects; 2) epileptic subjects during a seizure-free interval (interictal EEG); 3) epileptic subjects during a seizure (ictal EEG). The effectiveness of CD and LLE in differentiating between the three groups is investigated based on statistical significance of the differences. It is observed that while there may not be significant differences in the values of the parameters obtained from the original EEG, differences may be identified when the parameters are employed in conjunction with specific EEG subbands. Moreover, it is concluded that for the higher frequency beta and gamma subbands, the CD differentiates between the three groups, whereas for the lower frequency alpha subband, the LLE differentiates between the three groups.
Adeli
Hojjat
H
Department of Biomedical Engineering, The Ohio State University, 470 Hitchcock Hall, 2070 Neil Avenue, Columbus 43210, USA. adeli.1@osu.edu
Ghosh-Dastidar
Samanwoy
S
Dadmehr
Nahid
N
D000465:Algorithms; D001185:Artificial Intelligence; D003936:Diagnosis, Computer-Assisted / Q000379:methods*; D004569:Electroencephalography / Q000379:methods*; D004827:Epilepsy / Q000175:diagnosis*; D006801:Humans; D010363:Pattern Recognition, Automated / Q000379:methods*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity