[A case of Henoch-Schönlein purpura in a patient on hemodialysis].
Henoch-Schönlein purpura(HSP) is a systemic vasculitis and characterized by the tissue deposition of IgA-containing immune complexes. A 50-year-old man with end stage renal failure due to diabetic nephropathy on maintenance hemodialysis, presented purpura, hematuria, abdominal pain, and joint pain. He also presented a high fever with neutrophilia. Biopsy of skin lesions revealed inflammation of the small vessel accompanied by vascular IgA deposition. Based on the clinical symptoms and skin biopsy, we made the diagnosis of HSP. Oral prednisolone was administered resulting in an improvement of the clinical symptoms. A skin biopsy should be performed for histological and immunofluorescence studies in the case of clinical suspicion of HSP with end stage renal disease on hemodialysis.
Yoshino
Jun
J
Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan.
Sasamura
Hiroyuki
H
Konishi
Kohnosuke
K
Tsuji
Mihoko
M
Suda
Noriko
N
Yoshida
Testuya
T
Monkawa
Toshiaki
T
Hayashi
Matsuhiko
M
Itoh
Hiroshi
H
D000284:Administration, Oral; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage; D001706:Biopsy; D003928:Diabetic Nephropathies / Q000150:complications*; D006801:Humans; D011695:IgA Vasculitis / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D007676:Kidney Failure, Chronic / Q000150:complications / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D011239:Prednisolone / Q000008:administration & dosage; D006435:Renal Dialysis; D012867:Skin / Q000473:pathology
D000893:Anti-Inflammatory Agents; D011239:Prednisolone