title: [An association between tobacco smoking and basic haemodynamic parameters during induction of anaesthesia in gynecologic patients--a pilot study].
abstract: Cardiovascular risk is increased in cigarette smokers in the perioperative period and smoking cessation results in its decrease. The pilot study has been designed to assess an association between smoking and arterial blood pressure and heart rate during induction of anaesthesia in gynecologic patients. Significance of smoking cessation before operation in this respect should be also assessed. Systolic, diastolic and mean arterial blood pressures and heart rate were assessed before and after the induction of anaesthesia in gynecologic patients subjected to hysterectomy: 27 smokers and 27 non-smokers. Anxiety level and intraoperative fentanyl use were also analyzed. Examined parameters were compared between smokers who were abstinent for at least one day before operation and those who continued smoking. Arterial blood pressure and heart rate were comparable in both smokers and non-smokers and also in both groups before and after the induction of aneasthesia. Smoking did not result in any modulation of anxiety level and intraoperative fentanyl dosage. Smoking cessation was connected with lower mean arterial pressure before the induction (P = 0,037). Cigarette smoking does not modify values of basic haemodynamic parameters during induction of anaesthesia in gynecologic patients. Smoking abstinence for at least one day before surgery may be connected with a lower mean arterial blood pressure before the induction.
authors.affiliation: Zakład Anestezjologii Doświadczalnej, Akademia Medyczna, Poznań. hbillert@amp.edu.pl
authors.forename: Hanna
authors.initials: H
authors.lastname: Billert
authors.forename: Michał
authors.initials: M
authors.lastname: Gaca
authors.forename: Dariusz
authors.initials: D
authors.lastname: Adamski
mesh_terms: D000759:Adjuvants, Anesthesia / Q000008:administration & dosage; D000328:Adult; D000773:Anesthesia, Obstetrical; D001007:Anxiety / Q000209:etiology / Q000517:prevention & control; D001794:Blood Pressure; D018660:Blood Pressure Monitoring, Ambulatory; D015716:Electrocardiography, Ambulatory; D005260:Female; D005283:Fentanyl / Q000008:administration & dosage; D006339:Heart Rate; D006801:Humans; D007044:Hysterectomy / Q000009:adverse effects; D007432:Intraoperative Period; D008875:Middle Aged; D010865:Pilot Projects; D012907:Smoking / Q000503:physiopathology*; D016540:Smoking Cessation; D013599:Systole
chemical_list: D000759:Adjuvants, Anesthesia; D005283:Fentanyl