title: [The role of volume reduction surgery in the therapy of early stage chronic obstructive pulmonary disease].
abstract: The role of volume reduction surgery in the therapy of early stage chronic obstructive pulmonary disease. COPD is a leading cause of morbidity and mortality worldwide. Assessment of COPD severity is based on the level of patient's symptoms, the severity of the spirometric abnormality and the presence of complications, such as respiratory failure, and right heart failure. Management of mild to moderate COPD is complex, involves the avoidance of risk factors to prevent disease progression, pharmacotherapy as needed to control symptoms, physiotherapy, and rehabilitation. The bases of pharmacotherapy are bronchodilators, which represent the first line symptom based pharmacologic intervention in COPD. Surgical treatment of emphysema was basically designed to improve subjective dyspnoea, respiratory function and quality of life in severely disabled patients. Three surgical options are currently employed, namely bullectomy, lung volume surgery and lung transplantation. During volume reduction surgery the hyperinflated areas are resected, so the functional residual volume is getting reduced, the respiratory muscle function is increased; the quality of life is improved. The authors are report a young early stage COPD patient who underwent a volume reduction surgery because of decline in physical condition, improving her disability. In conclusion in properly selected patients, lung volume surgery can offer prolonged functional benefit and satisfactory long term survival, even in early stage. The invasive options has a risk of both mortality and morbidity, they are directed only at patients who remain symptomatic despite optimal medical treatment.
authors.affiliation: Debreceni Egyetem, Orvos és Egészségtudományi Centrum, Altalános Orvostudományi Kar, Tüdogyógyászati Klinika.
authors.forename: Attila
authors.initials: A
authors.lastname: Vaskó
authors.forename: Sándor
authors.initials: S
authors.lastname: Kiss
authors.forename: Katalin
authors.initials: K
authors.lastname: Dévényi
authors.forename: Csilla
authors.initials: C
authors.lastname: Ordög
authors.forename: Mária
authors.initials: M
authors.lastname: Szilasi
authors.forename: Eszter
authors.initials: E
authors.lastname: Csánky
mesh_terms: D000367:Age Factors; D001993:Bronchodilator Agents / Q000627:therapeutic use; D000075202:Contraindications; D005260:Female; D006801:Humans; D016040:Lung Transplantation / Q000592:standards; D008875:Middle Aged; D011013:Pneumonectomy; D029424:Pulmonary Disease, Chronic Obstructive / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000473:pathology / Q000503:physiopathology* / Q000601:surgery*; D011788:Quality of Life; D012129:Respiratory Function Tests; D012138:Respiratory Therapy; D012720:Severity of Illness Index; D013147:Spirometry; D014057:Tomography, X-Ray Computed
chemical_list: D001993:Bronchodilator Agents