title: [Impact of chronic obstructive pulmonary disease on activities of daily living: results of the EIME multicenter study].
abstract: OBJECTIVE
  The aim of this study was to determine the impact of chronic obstructive pulmonary disease (COPD) on activities of daily living in a large group of patients in Spain who responded to a specific questionnaire. A second aim was to explore the practical utility of the questionnaire and determine which variables could be used to identify "fragile" patients or patients in greater need of attention. To do this, we examined the relationship between questionnaire results and clinical variables, lung function measurements, socioeconomic status, and validated quality of life questionnaires.
  
  
  METHODS
  We conducted an observational, descriptive, multicenter, cross-sectional study in which 227 respiratory specialists from all over Spain collected data from 1057 patients with COPD. Each patient was given a specific questionnaire containing 7 items that measured the extent to which COPD affected different aspects of their lives. The patients rated each item on a scale of 0 to 2, depending on the level of impact. Total possible scores, thus, ranged from 0 to 14, and patients with a score of 9 or higher were classified as fragile. We then explored the relationship between questionnaire results and clinical variables, socioeconomic status, spirometric values, and quality of life as measured by the St George's Respiratory Questionnaire (SGRQ).
  
  
  RESULTS
  We studied 1057 patients (95.2% male) with a mean (SD) age of 67 (9) years and a mean predicted forced expiratory volume in 1 second (FEV1) of 41.8% (13.3%). The mean questionnaire score was 6.3 (3.1). The activities that were affected most were sport and leisure, habitual physical activity, and sex life (major impact reported by 52.5%, 30.3%, and 20.2% of patients, respectively). We found a correlation between questionnaire scores and known disease severity markers such as SGRQ scores, dyspnea, number of exacerbations, and FEV1 in liters. Patients included in the fragile category were older and had a lower socioeconomic status.
  
  
  CONCLUSIONS
  COPD impact questionnaire scores correlated well with SGRQ scores and the usual clinical variables and lung function measurements for evaluating disease severity (dyspnea, FEV1, and exacerbations). The questionnaire could, therefore, be a useful tool for identifying fragile patients who, in addition to having poorer clinical status and lung function measurements, have a lower socioeconomic status.
authors.affiliation: Servicio de Neumología, Red Respira RTIC 03/11 ISCIII, Hospital Virgen del Rocío, Sevilla, España. fag01se@saludalia.com
authors.forename: Francisco Javier
authors.initials: FJ
authors.lastname: Alvarez-Gutiérrez
authors.forename: Marc
authors.initials: M
authors.lastname: Miravitlles
authors.forename: Miriam
authors.initials: M
authors.lastname: Calle
authors.forename: Elena
authors.initials: E
authors.lastname: Gobartt
authors.forename: Francisco
authors.initials: F
authors.lastname: López
authors.forename: Antonio
authors.initials: A
authors.lastname: Martín
mesh_terms: D000203:Activities of Daily Living; D000368:Aged; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008297:Male; D029424:Pulmonary Disease, Chronic Obstructive / Q000150:complications*; D011788:Quality of Life; D011795:Surveys and Questionnaires