title: Heart and renal failure in renovascular hypertension caused by giant cell arteritis--case report.
abstract: We report a case of a male teenager with severe heart and acute renal failure as the dominant clinical manifestations of renovascular hypertension (RVH) caused by atypical giant cell arteritis (GCA). Unrecognized RVH and treatment of the consequent heart failure by angiotensin-converting enzyme inhibitors (ACEI) probably contributed to progression of renovascular disease to bilateral renal artery occlusion. Recurrent "flash" pulmonary edemas could not be prevented until surgical revascularization of the only functioning right kidney was achieved by an aortorenal bypass. Prompt post-operative normalization of heart function and arterial hypertension occurred despite the histopathological finding of the resected renal artery compatible with GCA and 4-year duration of significant renovascular disease. At the last check-up, the patient was asymptomatic, with normal arterial pressure on the prescribed treatment: carvedilol, hydrochlorothiazide, prednisolone 20 mg daily and aspirin. Subsequent follow-up is necessary to observe the evolution of GCA as an exceptionally rare cause of RVH.
authors.affiliation: Institute for Cardiovascular Diseases, Clinical Center of Serbia, Belgrade, Serbia.
authors.forename: D V
authors.initials: DV
authors.lastname: Kalimanovska-Ostric
authors.forename: S P
authors.initials: SP
authors.lastname: Simic-Ogrizovic
authors.forename: B M
authors.initials: BM
authors.lastname: Bonaci-Nikolic
authors.forename: V D
authors.initials: VD
authors.lastname: Bozic
authors.forename: V Z
authors.initials: VZ
authors.lastname: Ostric
authors.forename: L B
authors.initials: LB
authors.lastname: Davidovic
mesh_terms: D058186:Acute Kidney Injury / Q000209:etiology*; D000293:Adolescent; D013700:Giant Cell Arteritis / Q000150:complications* / Q000175:diagnosis; D006333:Heart Failure / Q000209:etiology*; D006801:Humans; D006978:Hypertension, Renovascular / Q000209:etiology*; D008297:Male; D011654:Pulmonary Edema / Q000209:etiology