Blood viscosity in patients with diffuse large B cell non-Hodgkin's lymphoma.
The aim of the study was to evaluate blood viscosity as possible marker of disease progression in patients with newly diagnosed non-Hodgkin's lymphoma (NHL).


METHODS
The viscosity of blood samples from 20 patients with newly diagnosed aggressive NHL (stage I, n=7; stage II, n=4; stage III, n=7; stage IV, n=2) was analyzed using Brookfield DV-II + (USA) machine.


RESULTS
Blood viscosity in NHL patients (median: 5.5+/-1.46 miliPascal) inversely correlated with lactatdehydrogenase (LDH) level, international prognostic index (IPI) score, and stage (p=0.02, r=-0.51; p=0.03, r=-0.63; and p=0.04, r=-0.45, respectively) and positively correlated with hemoglobin level (p=0.02, r=0.65)).


CONCLUSIONS
According to our data, blood viscosity may be considered as a follow up marker in NHL patients along with LDH level or sedimentation rate.
Utkan
G
G
Ankara Oncology Research and Training Hospital, Ankara, Turkey. gungorutkan_md@yahoo.com
Tek
I
I
Kocer
M
M
Muallaoglu
S
S
Durnal
A G
AG
Arslan
U Y
UY
Celenkoglu
G
G
Tokluoglu
S
S
Alkis
N
N
D000328:Adult; D000368:Aged; D001809:Blood Viscosity; D005260:Female; D006801:Humans; D016393:Lymphoma, B-Cell / Q000097:blood* / Q000473:pathology; D016403:Lymphoma, Large B-Cell, Diffuse / Q000097:blood* / Q000473:pathology; D008297:Male; D008875:Middle Aged