title: Quantitation of renal function based on two-compartmental modeling of renal pelvis.
abstract: The primary functions of the kidney are: (i) to get rid of the body waste materials that are either ingested or produced by metabolism, and (ii) to control the volume and composition of the body fluids. Herein, we provide a noninvasive methodology to assess physiological function of the kidneys. For this purpose, we analyze the renograms with 2-compartmental modelling of the kidney-renal outflow system, and therefrom compute the amount of flow of renal radionuclide into and out of the renal pelvis compartment. The derived information of uptake (k/A) and washout (e(beta/2V2)t sinhAt) rates can be of considerable use. The paper provides a number of case studies for the verification of the derived system governing equations against clinical renograms.
authors.affiliation: Sch. of Eng., Nanyang Polytech.
authors.forename: Loh
authors.initials: L
authors.lastname: Kah Meng
authors.forename: David
authors.initials: D
authors.lastname: Ng
authors.forename: Dhanjoo
authors.initials: D
authors.lastname: Ghista
authors.forename: Heiko
authors.initials: H
authors.lastname: Rudolph