title: Cell-based biosensors for single cell monitoring and drug analysis.
abstract: Cell-based biosensors incorporate cells as sensing elements that convert a change in immediate environment to signals conducive for processing. It characterizes with high sensitivity, excellent selectivity and fast response. Cell-based biosensors have been implemented for a number of applications ranging from pharmaceutical screening to environmental pollutant detection. This work demonstrate a novel cell-based biosensor following the principle of light-addressable potentiometric sensor and field effect transistor for detecting the action potential of single living cell under drugs. The experimental results agree with our expectation.
authors.affiliation: Department of Biomedical Engineering, Zhejiang University, Hangzhou, China. cnpwang@mail.bme.zju.edu.cn
authors.forename: Ping
authors.initials: P
authors.lastname: Wang
authors.forename: Gaixia
authors.initials: G
authors.lastname: Xu
authors.forename: Lifeng
authors.initials: L
authors.lastname: Qin
authors.forename: Ying
authors.initials: Y
authors.lastname: Xu
authors.forename: Yan
authors.initials: Y
authors.lastname: Li