title: Neuropsychological abnormalities in patients with dementia in CRF 01_AE HIV-1 infection.
abstract: HIV-associated dementia (HAD) is not firmly established in patients with circulating recombinant form (CRF) 01_AE HIV-1. In this study, we compared neuropsychological performance among 15 Thai individuals with HAD, 15 Thai individuals without HAD, and 30 HIV-negative control subjects. HIV-1 participants were highly active anti-retroviral therapy naive and matched by age, education, and CD4 count. Neuropsychological testing abnormalities were identified in most cognitive domains among HAD vs HIV-negative participants, confirming the presence of HAD in CRF01_AE.
authors.affiliation: Hawaii AIDS Clinical Research Program, John A. Burns School of Medicine, University of Hawaii, Honolulu, Hawaii, USA. Vvalcour@hawaii.edu
authors.forename: V G
authors.initials: VG
authors.lastname: Valcour
authors.forename: P
authors.initials: P
authors.lastname: Sithinamsuwan
authors.forename: S
authors.initials: S
authors.lastname: Nidhinandana
authors.forename: S
authors.initials: S
authors.lastname: Thitivichianlert
authors.forename: S
authors.initials: S
authors.lastname: Ratto-Kim
authors.forename: W
authors.initials: W
authors.lastname: Apateerapong
authors.forename: B T
authors.initials: BT
authors.lastname: Shiramizu
authors.forename: M S
authors.initials: MS
authors.lastname: Desouza
authors.forename: S T
authors.initials: ST
authors.lastname: Chitpatima
authors.forename: G
authors.initials: G
authors.lastname: Watt
authors.forename: T
authors.initials: T
authors.lastname: Chuenchitra
authors.forename: K R
authors.initials: KR
authors.lastname: Robertson
authors.forename: R H
authors.initials: RH
authors.lastname: Paul
authors.forename: J C
authors.initials: JC
authors.lastname: McArthur
authors.forename: J H
authors.initials: JH
authors.lastname: Kim
authors.forename: C M
authors.initials: CM
authors.lastname: Shikuma
mesh_terms: D015526:AIDS Dementia Complex / Q000097:blood / Q000523:psychology / Q000821:virology*; D000328:Adult; D003071:Cognition; D015331:Cohort Studies; D005260:Female; D015497:HIV-1 / Q000145:classification* / Q000235:genetics*; D006801:Humans; D008297:Male; D001523:Mental Disorders / Q000821:virology*; D009422:Nervous System Diseases / Q000821:virology*; D009483:Neuropsychological Tests; D011995:Recombination, Genetic; D012720:Severity of Illness Index