title: Gastric accumulation of bone seeking agent in a patient with advanced gastric cancer.
abstract: Soft tissue uptake of Tc-99m labeled bone seeking agents, such as Tc-99m 3,3-diphosphono-1,2-propanedicarboxylic acid (DPD), is commonly seen in clinical practice, even though bone scintigraphy is mainly used to detect bone disease. However, gastric uptake of bone agents in patients with gastric cancer is very rare. And it has been reported that calcified gastric adenocarcinoma appears in only about 5% of all gastric cancer. We report a rare case of bone scintigraphy, single photon emission computed tomography and computed tomography fusion images that demonstrated diffuse gastric uptake of Tc-99m DPD in a patient with advanced gastric cancer.
authors.affiliation: Department of Nuclear Medicine, Wonkwang University School of Medicine, Iksan, Korea.
authors.forename: Dae-Weung
authors.initials: DW
authors.lastname: Kim
authors.forename: Hwan-Jeong
authors.initials: HJ
authors.lastname: Jeong
authors.forename: Soon-Ah
authors.initials: SA
authors.lastname: Park
authors.forename: Chang-Guhn
authors.initials: CG
authors.lastname: Kim
mesh_terms: D000368:Aged; D001842:Bone and Bones / Q000000981:diagnostic imaging*; D004164:Diphosphonates / Q000493:pharmacokinetics*; D005753:Gastric Mucosa / Q000378:metabolism*; D006801:Humans; D008297:Male; D015609:Organotechnetium Compounds / Q000493:pharmacokinetics*; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals / Q000493:pharmacokinetics*; D013274:Stomach Neoplasms / Q000378:metabolism*
chemical_list: D004164:Diphosphonates; D015609:Organotechnetium Compounds; D019275:Radiopharmaceuticals; C033905:technetium Tc 99m 1,1-diphosphonopropane-2,3-dicarboxylic acid