title: [Brugada syndrome unmasked by lithium treatment].
abstract: BACKGROUND
  The Brugada syndrome is a rare genetic disease that can lead to death. Its diagnosis requires electrocardiography.
  
  
  METHODS
  A 36-year-old man was admitted with syncope. Brugada syndrome was diagnosed by the typical ECG pattern. The interaction between lithium therapy and ECG was shown clearly by the alternating type 1 and type 3 Brugada ECG patterns, depending on lithium status.
  
  
  CONCLUSIONS
  The Brugada syndrome may be unmasked by lithium therapy, due to its properties as a Na+ channel blocker, even at low doses. This case also demonstrated the usefulness of ECG in detecting the Brugada syndrome before and during lithium prescription.
authors.affiliation: Département de Cardiologie et Pathologies Vasculaires, CHU, Reims. sandras.r@wanadoo.fr
authors.forename: Raphael
authors.initials: R
authors.lastname: Sandras
authors.forename: Francois
authors.initials: F
authors.lastname: Lesaffre
authors.forename: Jérome
authors.initials: J
authors.lastname: Lacotte
authors.forename: Pierre
authors.initials: P
authors.lastname: Nazeyrollas
mesh_terms: D000328:Adult; D001714:Bipolar Disorder / Q000188:drug therapy; D053840:Brugada Syndrome / Q000175:diagnosis*; D004562:Electrocardiography; D006801:Humans; D018020:Lithium Compounds / Q000627:therapeutic use*; D008297:Male; D011619:Psychotropic Drugs / Q000627:therapeutic use*
chemical_list: D018020:Lithium Compounds; D011619:Psychotropic Drugs