title: Near infrared diffuse optical tomography: improving the quality of care in chronic wounds of patients with diabetes.
abstract: A frequency domain diffuse optical tomography instrument operating in the Near Infrared region (680-830nm) has been designed and used to monitor healing in diabetic wounds in a rat animal model. Instrument design and calibration are described and preliminary data of the in vivo experiment are reported. Excellent discrimination capability between the control and the diabetic population is possible, while the time course of impaired healing in diabetic animals appears to have different optical coefficients from the normal healing in the control group.
authors.affiliation: School of Biomedical Engineering and Physics Department, Drexel University, USA. esp25@drexel.edu
authors.forename: Elisabeth S
authors.initials: ES
authors.lastname: Papazoglou
authors.forename: Michael S
authors.initials: MS
authors.lastname: Weingarten
authors.forename: Leonid
authors.initials: L
authors.lastname: Zubkov
authors.forename: Linda
authors.initials: L
authors.lastname: Zhu
authors.forename: Som
authors.initials: S
authors.lastname: Tyagi
authors.forename: Kambiz
authors.initials: K
authors.lastname: Pourezaei
mesh_terms: D000818:Animals; D002908:Chronic Disease; D003920:Diabetes Mellitus; D023421:Models, Animal; D008991:Monitoring, Physiologic / Q000295:instrumentation; D011787:Quality of Health Care; D051381:Rats; D019265:Spectroscopy, Near-Infrared; D041622:Tomography, Optical / Q000295:instrumentation*; D014945:Wound Healing