Toxicity of extracts and isobutyl amides from Piper tuberculatum: potent compounds with potential for the control of the velvetbean caterpillar, Anticarsia gemmatalis.
The isobutyl amides pellitorine (compound 1) and 4,5-dihydropiperlonguminine (compound 2) were extracted from the seeds of Piper tuberculatum Jacq. (Piperaceae) in yields of 6.10 and 4.45% respectively. The acute toxicities to the velvetbean caterpillar, Anticarsia gemmatalis (Hübner) (Lepidoptera: Noctuidae), of extracts of seeds, leaves and stems of P. tuberculatum, and of compounds 1 and 2, were evaluated by means of contact bioassays. The extracts caused 80% mortality when doses higher than 800.00 microg insect(-1) of extract of seeds, leaves and stems were administered to the velvetbean caterpillars. Compounds 1 and 2 showed 100% mortality at doses of 200 and 700 microg insect(-1) respectively. The LD(50) and LD(90) values were respectively 31.3 and 104.5 microg insect(-1) for compound 1, and 122.3 and 381.0 microg insect(-1) for compound 2. The potential value of extracts and amides derived from P. tuberculatum as efficient insecticides against velvetbean caterpillars is discussed.
Navickiene
Hosana M Debonsi
HM
Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Universidade de São Paulo 14040903, Ribeirão Preto-SP, Brazil. hosana@fcfrp.usp.br
Miranda
José E
JE
Bortoli
Sérgio A
SA
Kato
Massuo J
MJ
Bolzani
Vanderlan S
VS
Furlan
Maysa
M
D000577:Amides / Q000737:chemistry / Q000302:isolation & purification; D000818:Animals; D052117:Benzodioxoles / Q000737:chemistry / Q000302:isolation & purification; D005231:Fatty Acids, Unsaturated / Q000737:chemistry / Q000302:isolation & purification; D007300:Insect Control; D007306:Insecticides / Q000737:chemistry / Q000302:isolation & purification; D009036:Moths; D031701:Piper / Q000737:chemistry*; D010936:Plant Extracts / Q000737:chemistry; D053284:Polyunsaturated Alkamides / Q000737:chemistry / Q000302:isolation & purification; D012639:Seeds / Q000737:chemistry
C521746:4,5-dihydropiperlonguminine; D000577:Amides; D052117:Benzodioxoles; D005231:Fatty Acids, Unsaturated; D007306:Insecticides; D010936:Plant Extracts; D053284:Polyunsaturated Alkamides; C008778:pellitorine