Maxillary sinus floor augmentation using autogenous bone grafts and platelet-enriched fibrin glue with simultaneous implant placement.
OBJECTIVE
The aim of this study was to evaluate the use of autogenous bone in combination with platelet-enriched fibrin glue as a grafting material for maxillary sinus augmentation with simultaneous implant placement in dogs.


METHODS
The mucous membranes of 12 sinuses in 6 dogs were elevated bilaterally. In the right sinus, autogenous bone mixed with platelet-enriched fibrin glue was grafted into the space between the membrane and the sinus wall. In the left sinus, autogenous bone alone was grafted as a control. At the same time, 2 dental implants were inserted into the grafting material through the maxillary sinus floor. The animals were killed 6 months after surgery.


RESULTS
The mean bone-implant contact was 40.5% on the fibrin glue side and 32.3% on the control side (P < .05). The mean height of newly formed bone in the augmented area was 12.2 mm on the fibrin glue side and 10.7 mm on the control side (P < .05).


CONCLUSIONS
The results indicate that the use of autogenous bone mixed with platelet-enriched fibrin glue can achieve results superior to those for grafts of autogenous bone alone. The specific improvements of this technique include enhanced osseointegration of dental implants and increased height of new bone.
Lee
Hyeon-Jung
HJ
Department of Oral and Maxillofacial Surgery, College of Dentistry, Yonsei University, Seoul, South Korea.
Choi
Byung-Ho
BH
Jung
Jae-Hyung
JH
Zhu
Shi-Jiang
SJ
Lee
Seoung-Ho
SH
Huh
Jin-Young
JY
You
Tae-Min
TM
Li
Jingxu
J
D000818:Animals; D001861:Bone Regeneration / Q000187:drug effects*; D016025:Bone Transplantation / Q000379:methods*; D003758:Dental Implantation, Endosseous; D004285:Dogs; D005260:Female; D015718:Fibrin Tissue Adhesive / Q000494:pharmacology*; D008443:Maxillary Sinus / Q000601:surgery*; D023421:Models, Animal; D013516:Oral Surgical Procedures, Preprosthetic / Q000379:methods*; D053657:Platelet-Rich Plasma; D018709:Statistics, Nonparametric
D015718:Fibrin Tissue Adhesive