Absence of tooth staining with doxycycline treatment in young children.
The aim of the study was to determine if doxycycline causes tooth staining in young children. A dentist examined 31 randomized children who had been treated with doxycycline and 30 children who had not received doxycycline. Mean age of the children was 10.4 -/+ 2.1 years. Mean age at receipt of the first doxycycline treatment was 4.1 -/+ 1.6 years, and mean number of doxycycline courses was 2.0 -/+ 1.3. No tooth staining was detected by the dentist in any of the children in either group. These findings indicate that treatment with doxycycline in children aged 2 to 8 years is not associated with tooth staining.
Volovitz
Benjamin
B
Department of Pediatrics C, Asthma Clinic, Schneider Children's Medical Center of Israel, 14 Kaplan Street, Petah Tiqwa 49202, Israel. Benjamin@Volovitz.com
Shkap
Ronit
R
Amir
Jacob
J
Calderon
Shlomo
S
Varsano
Izhak
I
Nussinovitch
Moshe
M
D000293:Adolescent; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000009:adverse effects*; D001249:Asthma / Q000188:drug therapy*; D002648:Child; D004318:Doxycycline / Q000008:administration & dosage / Q000009:adverse effects*; D004334:Drug Administration Schedule; D006801:Humans; D009910:Oral Hygiene; D016037:Single-Blind Method; D014075:Tooth Discoloration / Q000139:chemically induced*
D000900:Anti-Bacterial Agents; D004318:Doxycycline