Transcriptome analysis of rat kidney cells continuously exposed to cadmium using DNA microarray.
To examine the transcriptional responses of rat kidney cells continuously exposed to cadmium, we performed DNA microarray analysis. Cadmium increased levels of expression of 27 genes, including genes for Mt1, Mt2, GSTa3 and B2m and reduced those of 4 genes.
Ohba
Ken-ichi
K
Department of Health Administration, School of Allied Health Sciences, Kitasato University, 1-15-1 Kitasato, Sagamihara, Kanagawa 228-8555, Japan. kohba@kitasato-u.ac.jp
Okawa
Youhei
Y
Matsumoto
Yuki
Y
Nakamura
Yasuhiro
Y
Ohta
Hisayoshi
H
D000818:Animals; D002104:Cadmium / Q000633:toxicity*; D005260:Female; D007668:Kidney / Q000166:cytology* / Q000187:drug effects*; D020411:Oligonucleotide Array Sequence Analysis; D051381:Rats; D017208:Rats, Wistar; D014158:Transcription, Genetic / Q000187:drug effects*
D002104:Cadmium