title: High-resolution nuclear magnetic resonance spectroscopy studies of polysaccharides crosslinked by sodium trimetaphosphate: a proposal for the reaction mechanism.
abstract: An NMR spectroscopy study ((31)P, (1)H, (13)C) of the postulated crosslinking mechanism of sodium trimetaphosphate (STMP) on polysaccharides is reported using methyl alpha-D-glucopyranoside as a model. In a first step, reaction of STMP with Glc-OMe gives grafted sodium tripolyphosphate (STPP(g)). On the one hand, STTP(g) can react with a second alcohol functionality to give a crosslinked monophosphate. On the other hand, a monophosphate (grafted phosphate) could be obtained by alkaline degradation of STPP(g). NMR spectroscopy allows to detect the various species formed and to obtain the crosslinking density of STMP-polysaccharides hydrogels.
authors.affiliation: UMR 6522, CNRS-Université de Rouen, Laboratoire Polymères, Biopolymères et Membranes, F-76821 Mont Saint Aignan, France.
authors.forename: Stéphane
authors.initials: S
authors.lastname: Lack
authors.forename: Virginie
authors.initials: V
authors.lastname: Dulong
authors.forename: Luc
authors.initials: L
authors.lastname: Picton
authors.forename: Didier
authors.initials: D
authors.lastname: Le Cerf
authors.forename: Eric
authors.initials: E
authors.lastname: Condamine
mesh_terms: D003432:Cross-Linking Reagents / Q000032:analysis* / Q000737:chemistry; D005936:Glucans / Q000737:chemistry; D020100:Hydrogels / Q000138:chemical synthesis / Q000737:chemistry; D006863:Hydrogen-Ion Concentration; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D015394:Molecular Structure; D011122:Polyphosphates / Q000032:analysis* / Q000737:chemistry; D011134:Polysaccharides / Q000032:analysis* / Q000737:chemistry
chemical_list: D003432:Cross-Linking Reagents; D005936:Glucans; D020100:Hydrogels; D011122:Polyphosphates; D011134:Polysaccharides; C009109:pullulan; C009293:trimetaphosphoric acid