Karyomegalic interstitial nephritis: a pitfall in urine cytology.
A case of a 44-yr-old Maori female presenting with chronic renal failure due to karyomegalic interstitial nephritis is reported. To our knowledge, this is the first instance this disorder has been reported in a New Zealand Maori. Karyomegalic interstitial nephritis is a rare cause of progressive renal failure, which may be familial, and is frequently associated with a history of recurrent respiratory infections. The urine in this case contained large, pleomorphic cells, mimicking carcinoma. The case therefore illustrates a rare cause of chronic renal failure, and presents an important diagnostic pitfall in the practice of urine cytopathology.
Palmer
David
D
Department of Cytology, Wellington Hospital and School of Medicine, Capital and Coast District Health Board, Wellington, New Zealand. david.palmer@ccdhb.org.nz
Lallu
Sharda
S
Matheson
Philip
P
Bethwaite
Peter
P
Tompson
Keneth
K
D000328:Adult; D005260:Female; D006801:Humans; D007668:Kidney / Q000473:pathology; D009395:Nephritis, Interstitial / Q000473:pathology* / Q000652:urine*