title: An insertion/deletion in the porcine FGFR2 gene.
abstract: The 7000-rad INRA-University of Minnesota porcine Radiation Hybrid panel was used to localize the FGFR2 gene on Sus scrofa chromosome 14 (SSC14). An insertion/deletion mutation of approximately 240 bp was detected in the porcine FGFR2 gene. This mutation consists of a repeat motif of 48 bp. In a short and long variant of this polymorphism, the motif was repeated either six or 11 times. The mutation was shown to follow a Mendelian mode of inheritance in 10 families including 48 pigs of Large White x Duroc origin.
authors.affiliation: Centre for Advanced Technologies in Animal Genetics and Reproduction (Reprogen), Faculty of Veterinary Science, University of Sydney, NSW, Australia.
authors.forename: J
authors.initials: J
authors.lastname: Aldenhoven
authors.forename: A
authors.initials: A
authors.lastname: Spötter
authors.forename: O
authors.initials: O
authors.lastname: Distl
mesh_terms: D000818:Animals; D033481:Chromosomes, Mammalian / Q000235:genetics*; D017931:DNA Primers; D004591:Electrophoresis, Polyacrylamide Gel; D040582:Inheritance Patterns; D010375:Pedigree; D021101:Radiation Hybrid Mapping; D051497:Receptor, Fibroblast Growth Factor, Type 2 / Q000235:genetics*; D012091:Repetitive Sequences, Nucleic Acid / Q000235:genetics*; D017384:Sequence Deletion / Q000235:genetics*; D034421:Sus scrofa / Q000235:genetics*
chemical_list: D017931:DNA Primers; D051497:Receptor, Fibroblast Growth Factor, Type 2