title: Generation of acylnitroso dienophiles: a study of metal catalysis.
abstract: Four novel metal/amine catalysts efficiently converted Boc-NHOH to its acylnitroso species at 5 mol % catalyst loading. These reactions allowed the preparation of polyfunctional hetero Diels-Alder adducts in high yield and from truly commercially available materials.
authors.affiliation: Centre for Synthesis and Chemical Biology (CSCB), Department of Pharmaceutical and Medicinal Chemistry, The Royal College of Surgeons in Ireland, 123 St. Stephen's Green, Dublin 2, Dublin, Ireland. madamo@rcsi.ie
authors.forename: Mauro F A
authors.initials: MF
authors.lastname: Adamo
authors.forename: Simone
authors.initials: S
authors.lastname: Bruschi
mesh_terms: D000215:Acylation; D000588:Amines / Q000737:chemistry; D002384:Catalysis; D008670:Metals / Q000737:chemistry*; D015394:Molecular Structure; D009603:Nitroso Compounds / Q000138:chemical synthesis / Q000737:chemistry*; D010084:Oxidation-Reduction
chemical_list: D000588:Amines; D008670:Metals; D009603:Nitroso Compounds