title: [An unusual localization of a rare tumor: giant-cell tumor of the rib. Case report and review of the literature].
abstract: BACKGROUND
  Giant-cell tumors of bone are rare primary neoplasms commonly encountered in young adults. Women are slightly more affected than men.
  
  
  METHODS
  We report the case a 27 year old woman presenting with a twelve months history of painful and progressively growing thoracic mass in the right anterior chest wall. Physical examination found out a fixed thoracic mass in the right retro-mammary area measuring 8 x 6 centimeters. The overlying skin was normal. Chest roentgenogram demonstrated a large ill defined mass continuing the anterior arc of the fourth right rib. Computed tomography evidenced a well defined pathologic process originating from the fourth right rib without expansion of the surrounding soft tissue. Pulmonary functional tests were normal and other complementary investigations evidenced no abnormalities. Our patient first had a fine needle cytological biopsy that brought strong suspicion of Giant-cell tumor of the rib. She then underwent an "en bloc" resection of the tumor whose histopathologic analysis allowed a definitive diagnosis. The post-surgical follow up during 12 months showed no signs of tumor recurrence.
  
  
  CONCLUSIONS
  Through this observation the authors emphasize not only the rarity of the giant-cell tumors of bone but also its unusual costal localization (few cases reported till date). They focus on the importance of precocious screening and treatment and underline the value of the follow up in order to detect timely any sign of local recurrence or sarcomatous transformation. Finally, they report a current review of the literature.
authors.affiliation: Service de pneumologie, Hôpital Ibn Sina, C.H.U de Rabat, Maroc. ibnsellam2000@yahoo.fr
authors.forename: A
authors.initials: A
authors.lastname: Ibn Sellam
authors.forename: A
authors.initials: A
authors.lastname: Chaibainou
authors.forename: A
authors.initials: A
authors.lastname: Achir
authors.forename: A
authors.initials: A
authors.lastname: Allouch
authors.forename: Z
authors.initials: Z
authors.lastname: Bernoussi
authors.forename: A
authors.initials: A
authors.lastname: Jahid
authors.forename: N
authors.initials: N
authors.lastname: Mahassini
authors.forename: L
authors.initials: L
authors.lastname: Achachi
authors.forename: M
authors.initials: M
authors.lastname: El Ftouh
authors.forename: A
authors.initials: A
authors.lastname: Benosman
authors.forename: M T
authors.initials: MT
authors.lastname: El Fassy Fihry
mesh_terms: D000328:Adult; D001859:Bone Neoplasms / Q000000981:diagnostic imaging / Q000601:surgery*; D005260:Female; D018212:Giant Cell Tumor of Bone / Q000000981:diagnostic imaging / Q000601:surgery*; D006801:Humans; D012272:Ribs; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome