title: [Association of polymorphic markers D6S2414 and D6S1271 located in the MHC locus (6p21.31) with chronic glomerulonephritis in the Russian population of Moscow].
abstract: The distributions of the alleles and genotypes of Polymorphic markers D6S2414 and D6S1271 located among class II MHC genes have been studied in patients with chronic glomerulonephritis (CGN) and healthy donors. Both markers have been found to be associated with the disease. Since these microsatellites are located in the chromosomal region occupied by class II MHC genes, their association with CGN indirectly indicates that class II MHC genes are involved in the development of this pathology.
authors.forename: A E
authors.initials: AE
authors.lastname: Shestakov
authors.forename: E S
authors.initials: ES
authors.lastname: Kamyshova
authors.forename: I M
authors.initials: IM
authors.lastname: Kutyrina
authors.forename: K V
authors.initials: KV
authors.lastname: Sevost'ianov
authors.forename: V V
authors.initials: VV
authors.lastname: Nosikov
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002908:Chronic Disease; D005260:Female; D005787:Gene Frequency; D005802:Genes, MHC Class II / Q000235:genetics*; D005819:Genetic Markers; D005921:Glomerulonephritis / Q000235:genetics*; D006681:HLA-D Antigens / Q000235:genetics*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009031:Moscow; D011110:Polymorphism, Genetic; D044465:White People / Q000235:genetics
chemical_list: D005819:Genetic Markers; D006681:HLA-D Antigens