Successful mitral valve replacement in a patient with a severe form of beta-thalassaemia.
beta-Thalassaemia is an inherited haemoglobin (Hb) disorder resulting in chronic haemolytic anaemia. The most anaemic patients require regular red blood cell (RBC) transfusions for survival but iron accumulation leads to multisystem dysfunction. Heart complications represent the leading cause of mortality in beta-thalassaemia patients. In this case report we present a successful mitral valve replacement (MVR) in a patient with a severe form of beta-thalassaemia.
Botta
Luca
L
Department of Cardiac Surgery, University of Bologna, Bologna, Italy.
Savini
Carlo
C
Martin-Suarez
Sofia
S
Dell' Amore
Andrea
A
Camurri
Nicola
N
Arpesella
Giorgio
G
Di Bartolomeo
Roberto
R
D001803:Blood Transfusion; D005500:Follow-Up Studies; D019918:Heart Valve Prosthesis Implantation / Q000379:methods*; D006801:Humans; D008297:Male; D008875:Middle Aged; D008944:Mitral Valve Insufficiency / Q000175:diagnosis / Q000209:etiology* / Q000601:surgery*; D019990:Perioperative Care / Q000379:methods; D018570:Risk Assessment; D012720:Severity of Illness Index; D016896:Treatment Outcome; D017086:beta-Thalassemia / Q000150:complications* / Q000175:diagnosis