title: [Bacterial meningitis with Campylobacter fetus manifesting chronic clinical course].
abstract: A 43-year-old man with no past history of underlying disease was admitted to an affiliated hospital, complaining of high fever and severe headache. Polynuclear dominant pleocytosis in the cerebrospinal fluid (CSF) suggested bacterial meningitis. He was immediately treated with several antibiotics, then his clinical symptoms improved, although intractable headache relapsed after withdrawal of the initial therapy. Thereafter he consulted our hospital for a second opinion. CSF examination in our hospital demonstrated mononuclear dominant pleocytosis with normal sugar value. However, bacterial culture of the CSF specimen yielded a gram-negative bacillus that was finally identified as a Campylobacter fetus on Skirrow's culture. Treatment with meropenem and other antibiotics improved both the clinical symptoms and CSF findings. Thus, meningitis with a Campylobacter fetus could manifest a chronic and atypical clinical course, careful attention should be paid to establish an early diagnosis.
authors.affiliation: Department of Neurology, Kinki University School of Medicine.
authors.forename: Mitsuaki
authors.initials: M
authors.lastname: Shioyama
authors.forename: Yoshiyuki
authors.initials: Y
authors.lastname: Mitui
authors.forename: Haruo
authors.initials: H
authors.lastname: Ueda
authors.forename: Kazuo
authors.initials: K
authors.lastname: Takada
authors.forename: Jyuri
authors.initials: J
authors.lastname: Kureshiro
authors.forename: Masataka
authors.initials: M
authors.lastname: Kitaguchi
authors.forename: Susumu
authors.initials: S
authors.lastname: Kusunoki
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002169:Campylobacter Infections / Q000188:drug therapy / Q000382:microbiology* / Q000503:physiopathology; D002168:Campylobacter fetus; D002908:Chronic Disease; D006801:Humans; D008297:Male; D016920:Meningitis, Bacterial / Q000188:drug therapy / Q000382:microbiology* / Q000503:physiopathology; D000077731:Meropenem; D013845:Thienamycins / Q000627:therapeutic use
chemical_list: D000900:Anti-Bacterial Agents; D013845:Thienamycins; D000077731:Meropenem