Generation of phosphorus-centered radicals via homolytic substitution at sulfur.
A novel radical domino process relying on the homolytic cleavage of P-S bonds allows the preparation of phosphorus-containing molecules through addition of P-centered radicals onto olefins. The key step of this reaction is a homolytic substitution on a sulfur atom. The scope of the reaction is broad. Diaminophosphonyl radicals whose reactivity was unknown react smoothly with olefins. Use of tin hydride can be avoided. A radical thiophosphinoylation of triple bonds has been uncovered. [reaction: see text]
Carta
Paola
P
Université Pierre et Marie Curie-Paris 6, Laboratoire de chimie organique (UMR CNRS 7611), Institut de chimie moléculaire (FR 2769), 4 place Jussieu, C. 229, 75005 Paris, France.
Puljic
Nicolas
N
Robert
Carine
C
Dhimane
Anne-Lise
AL
Fensterbank
Louis
L
Lacôte
Emmanuel
E
Malacria
Max
M