title: Surface plasmon resonance imaging using a high numerical aperture microscope objective.
abstract: We designed, constructed, and tested a surface plasmon resonance (SPR) microscope using a high numerical aperture objective from a commercially available inverted optical microscope. Such a configuration, combined with various methods to shorten the surface plasmon propagation length, achieves diffraction-limited spatial resolution in the transverse direction and near-diffraction-limited resolution in the longitudinal direction. A virtue of the objective-type SPR imaging is that we achieve distortion-free angle-resolved SPR imaging, allowing the angle-dependent reflectivity of the sample to be examined on a pixel-by-pixel basis, thus offering high-resolution information about surface properties.
authors.affiliation: Department of Chemistry, Stanford University, Stanford, California 94305-5080, USA.
authors.forename: Bo
authors.initials: B
authors.lastname: Huang
authors.forename: Fang
authors.initials: F
authors.lastname: Yu
authors.forename: Richard N
authors.initials: RN
authors.lastname: Zare