title: MRI characterization of myocardial tissue in patients with Fabry's disease.
abstract: OBJECTIVE
  Fabry's disease is a multisystem X-linked disorder of lysosomal metabolism frequently associated with left ventricular (LV) hypertrophy. In this study, we aimed to assess whether myocardial T2 relaxation time determined by a black blood multiecho multishot MRI sequence could be used to evaluate cardiac involvement in patients with Fabry's disease.
  
  
  CONCLUSIONS
  Myocardial T2 relaxation time is prolonged in patients with Fabry's disease compared with that of hypertrophic patients and healthy control subjects. MRI may be useful for the characterization of myocardial tissue in patients with Fabry's disease.
authors.affiliation: Department of Radiology, University Federico II, Via Pansini 5, Via Posillipo 196, Napoli 80123, Italy. mimbriaco@hotmail.com
authors.forename: Massimo
authors.initials: M
authors.lastname: Imbriaco
authors.forename: Letizia
authors.initials: L
authors.lastname: Spinelli
authors.forename: Alberto
authors.initials: A
authors.lastname: Cuocolo
authors.forename: Simone
authors.initials: S
authors.lastname: Maurea
authors.forename: Giacomo
authors.initials: G
authors.lastname: Sica
authors.forename: Mario
authors.initials: M
authors.lastname: Quarantelli
authors.forename: Antonio
authors.initials: A
authors.lastname: Pisani
authors.forename: Raffaele
authors.initials: R
authors.lastname: Liuzzi
authors.forename: Bruno
authors.initials: B
authors.lastname: Cianciaruso
authors.forename: Massimo
authors.initials: M
authors.lastname: Sabbatini
authors.forename: Marco
authors.initials: M
authors.lastname: Salvatore
mesh_terms: D000293:Adolescent; D000328:Adult; D009202:Cardiomyopathies / Q000150:complications* / Q000473:pathology*; D000795:Fabry Disease / Q000150:complications* / Q000473:pathology*; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged