title: Highly diastereoselective preparation of (E)-alkenylsilanes bearing an alpha-chiral center.
abstract: The copper(I)-mediated anti-S(N)2' allylic substitution allows a highly stereoselective preparation of alkenylsilanes bearing a chiral center in the alpha-position with high transfer of chirality. These alkenylsilanes were converted into alpha,beta-unsaturated ketones or into the corresponding boronic esters without loss of the chiral information. [reaction: see text]
authors.affiliation: Department Chemie und Biochemie, Ludwig-Maximilians-Universität, Butenandtstrasse 5-13, D-81377 München, Germany.
authors.forename: Sylvie
authors.initials: S
authors.lastname: Perrone
authors.forename: Paul
authors.initials: P
authors.lastname: Knochel