title: Depressed-type of early colon cancer with extensive lymph node metastasis.
abstract: Early colorectal cancer (ECC) is defined as invasive tumor limited to the colonic and rectal mucosa or submucosa, regardless of the presence or absence of lymph node metastasis. The incidence of lymph node metastasis in ECC ranges from 0 to 15.4%, and risk factors include depth of submucosal invasion, growth patterns (polypoid or non-polypoid), histologic subclassification, and lymphatic invasion. Of non-polypoid growth patterns, the depressed types of colorectal cancer have higher malignant potential than polypoid types, even for small sizes. Unfortunately, this type is also difficult to detect on colonoscopic examination. In this report, we describe a case of depressed type ECC with extensive lymph node metastasis without regional lymph node involvement.
authors.affiliation: Department of Gastroenterology, Yonsei University Medical Center, 134 Sinchon-dong, Seodaemum-gu, 120-752 Seoul, Korea.
authors.forename: Sung Ai
authors.initials: SA
authors.lastname: Kim
authors.forename: Jin Hyoung
authors.initials: JH
authors.lastname: Lee
authors.forename: Soo Young
authors.initials: SY
authors.lastname: Park
authors.forename: Hoguen
authors.initials: H
authors.lastname: Kim
authors.forename: Tae Il
authors.initials: TI
authors.lastname: Kim
authors.forename: Won Ho
authors.initials: WH
authors.lastname: Kim
mesh_terms: D000368:Aged; D003110:Colonic Neoplasms / Q000473:pathology*; D003113:Colonoscopy; D005260:Female; D006801:Humans; D008207:Lymphatic Metastasis; D049268:Positron-Emission Tomography