Ag+ -assisted hydrosilylation: complementary behavior of Rh and Ir catalysts (reversal of enantioselectivity).
[structure: see text]. The presence of a suitably situated hydroxy function in a PHOX ligand leads to an enhancement of the enantioselectivity in Rh-catalyzed hydrosilylations of prochiral ketones in the presence of AgBF4 (95% ee for acetophenone as compared to 75% using i-Pr-phosphinooxazoline (PHOX)). Exchanging Rh for Ir affords the product with the opposite absolute configuration (78% ee).
Frölander
Anders
A
KTH School of Chemical Science and Engineering, Organic Chemistry, SE 100 44 Stockholm, Sweden.
Moberg
Christina
C