title: Phytotoxicity of secondary metabolites from Aptenia cordifolia.
abstract: From the fresh leaves or twigs of Aptenia cordifolia, a total of 29 compounds were isolated, including the new tetranoroxyneolignan 18, the new dilignan 19, and the beta-ionone derivative 27, previously only known as a synthetic compound, together with 26 known compounds. The structures of the new products were determined by (1)H-, (13)C-, and 2D-NMR, as well as HR-MS analyses. The phytotoxic effects of the isolates on the germination and growth of the dicotyledon Lactuca sativa L. (lettuce) were studied in the concentration range 10(-4) to 10(-7) M. Several constituents of A. cordifolia were found to be equally active as or superior to 4-hydroxybenzoic acid (HBA) used as positive control.
authors.affiliation: Dipartimento di Chimica Organica e Biochimica, Università Federico II, Complesso Universitario Monte Sant'Angelo, Via Cintia 4, I-80126 Napoli, Italy. dellagre@unina.it
authors.forename: Marina
authors.initials: M
authors.lastname: DellaGreca
authors.forename: Antonio
authors.initials: A
authors.lastname: Fiorentino
authors.forename: Angelina
authors.initials: A
authors.lastname: Izzo
authors.forename: Filomena
authors.initials: F
authors.lastname: Napoli
authors.forename: Raffaella
authors.initials: R
authors.lastname: Purcaro
authors.forename: Armando
authors.initials: A
authors.lastname: Zarrelli
mesh_terms: D035722:Aizoaceae / Q000737:chemistry / Q000378:metabolism*; D018525:Germination / Q000187:drug effects; D018545:Lactuca / Q000187:drug effects; D017705:Lignans / Q000737:chemistry / Q000302:isolation & purification / Q000633:toxicity; D009682:Magnetic Resonance Spectroscopy; D008968:Molecular Conformation
chemical_list: D017705:Lignans