The role of statins in erectile dysfunction.
Erectile dysfunction is a common disorder that involves impairment of the vascular endothelium and has been associated with cardiovascular disease. Despite the general effectiveness of phosphodiesterase type 5 (PDE5) inhibitors, some erectile dysfunction patients are resistant to or do not tolerate treatment with them, thus requiring further treatment alternatives. Statins have emerged as a promising therapeutic option due to their multiple modes of action. The use of statins as adjuvant or alternative therapy in erectile dysfunction has opened new avenues for the treatment of this disorder.
Ferrer
Elisa
E
Medical Information Department, Prous Science, Barcelona, Spain. journals@prous.com
Moral
Maria Angels
MA
Bozzo
Jordi
J
D002318:Cardiovascular Diseases / Q000150:complications; D004357:Drug Synergism; D004359:Drug Therapy, Combination; D007172:Erectile Dysfunction / Q000188:drug therapy*; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000494:pharmacology* / Q000627:therapeutic use*; D008297:Male; D010410:Penile Erection / Q000502:physiology*; D010726:Phosphodiesterase Inhibitors / Q000627:therapeutic use*
D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D010726:Phosphodiesterase Inhibitors