title: Genetic polymorphisms of folate metabolic enzymes and toxicities of high dose methotrexate in children with acute lymphoblastic leukemia.
authors.forename: Samart
authors.initials: S
authors.lastname: Pakakasama
authors.forename: Kittima
authors.initials: K
authors.lastname: Kanchanakamhaeng
authors.forename: Saowanee
authors.initials: S
authors.lastname: Kajanachumpol
authors.forename: Umaporn
authors.initials: U
authors.lastname: Udomsubpayakul
authors.forename: Nongnuch
authors.initials: N
authors.lastname: Sirachainan
authors.forename: Amnuay
authors.initials: A
authors.lastname: Thithapandha
authors.forename: Suradej
authors.initials: S
authors.lastname: Hongeng
mesh_terms: D000293:Adolescent; D000964:Antimetabolites, Antineoplastic / Q000009:adverse effects* / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D005260:Female; D005492:Folic Acid / Q000378:metabolism; D005493:Folic Acid Antagonists / Q000009:adverse effects / Q000627:therapeutic use; D006801:Humans; D007223:Infant; D008297:Male; D008727:Methotrexate / Q000009:adverse effects* / Q000627:therapeutic use; D008780:Methyltransferases / Q000235:genetics* / Q000378:metabolism; D011110:Polymorphism, Genetic; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000188:drug therapy* / Q000201:enzymology / Q000235:genetics*
chemical_list: D000964:Antimetabolites, Antineoplastic; D005493:Folic Acid Antagonists; D005492:Folic Acid; D008780:Methyltransferases; C022745:thiopurine methyltransferase; D008727:Methotrexate