Microenvironmental adaptations in the parotid of ferret investigated by electron microscopy.
Previous histochemical investigations suggested that the microenvironment in the parotid of ferret would foster microlithiasis because of a combination of pockets of inefficient secretion, brisk phagy and secretory material rich in calcium. We have undertaken the present ultrastructural investigation in an attempt to provide corroborative evidence. Parotids from four normal ferrets were examined by electron microscopy. Phagosomes in which there was cellular debris and occasionally secretory granules were present in acinar cells, which indicates crinophagy, and residual bodies were present in ductal cells. Atrophic parenchymal cells, degenerate parenchymal cells and apoptotic bodies were present. Cellular debris and secretory material were present in lumina, which indicates stagnation. The results indicate that removal of redundant secretory material and cells and low flow of saliva are features of the parotid of ferret and support the concept of pockets of inefficient secretory activity.
Triantafyllou
Asterios
A
Oral Pathology, Department & School of Dental Studies, The University of Liverpool, Liverpool, UK. A.Triantafyllou@liverpool.ac.uk
Harrison
John D
JD
Garrett
John R
JR
D000222:Adaptation, Physiological / Q000502:physiology*; D000818:Animals; D017209:Apoptosis; D001284:Atrophy; D001485:Basement Membrane / Q000648:ultrastructure; D002462:Cell Membrane / Q000648:ultrastructure; D004396:Coloring Agents; D018870:Endoplasmic Reticulum, Rough / Q000648:ultrastructure; D005289:Ferrets; D006056:Golgi Apparatus / Q000648:ultrastructure; D008751:Methylene Blue; D008854:Microscopy, Electron; D008871:Microvilli / Q000648:ultrastructure; D008928:Mitochondria / Q000648:ultrastructure; D010306:Parotid Gland / Q000378:metabolism / Q000648:ultrastructure*; D010588:Phagosomes / Q000648:ultrastructure; D012463:Saliva / Q000378:metabolism; D018987:Salivary Ducts / Q000378:metabolism / Q000648:ultrastructure; D012636:Secretory Rate / Q000502:physiology; D022142:Secretory Vesicles / Q000648:ultrastructure
D004396:Coloring Agents; D008751:Methylene Blue