title: [Bcl-2 expression following the brain concussion in rats].
abstract: OBJECTIVE
  To evaluate the expression of Bcl-2 protein after brain concussion.
  
  
  METHODS
  Expression levels of Bel-2 protein in cortex, pontine and cerebellum of rats were investigated using immunohistochemistry.
  
  
  RESULTS
  There was no expression of Bcl-2 protein in control group seen. The expression of Bcl-2 protein in brain concussion groups was detected at l hour, and the expression level reached its peak 4 days after the concussion and then declined gradually.
  
  
  CONCLUSIONS
  Our findings suggest that the detection of Bel-2 protein could be an indicator for diagnosis of brain concussion and for estimation of the post injury time interval.
authors.affiliation: Department of Forensic Medicine, Wannan Medical College, Wuhu 241001, China.
authors.forename: Xu-yang
authors.initials: XY
authors.lastname: Zhu
authors.forename: Feng
authors.initials: F
authors.lastname: Wang
authors.forename: Wei-hua
authors.initials: WH
authors.lastname: Fang
authors.forename: Mao-wang
authors.initials: MW
authors.lastname: Wu
mesh_terms: D000818:Animals; D001921:Brain / Q000378:metabolism / Q000473:pathology; D001924:Brain Concussion / Q000378:metabolism*; D001933:Brain Stem / Q000378:metabolism* / Q000473:pathology; D002540:Cerebral Cortex / Q000378:metabolism* / Q000473:pathology; D003288:Contusions / Q000378:metabolism / Q000473:pathology; D004195:Disease Models, Animal; D005260:Female; D007150:Immunohistochemistry; D008297:Male; D009474:Neurons / Q000378:metabolism / Q000473:pathology; D019253:Proto-Oncogene Proteins c-bcl-2 / Q000378:metabolism*; D051381:Rats; D017207:Rats, Sprague-Dawley; D013997:Time Factors
chemical_list: D019253:Proto-Oncogene Proteins c-bcl-2