title: [Anti-mite activities of 25 kinds of traditional Chinese medicines for Demodex folliculorum].
abstract: OBJECTIVE
  To explore traditional Chinese medicines (TCMs) with anti-mite activities for Dernodex folliculorum in vitro.
  
  
  METHODS
  Active Demodex folliculorum were selected from patients with moderate to severe Demodex infestation. A total of 25 TCMs were individually extracted with 80% ethanol by heat under reflux, and then prepared to be concentration of 200 mg/ml. The extractions were used individually in mite-killing experiment in vitro to judge anti-mite activity by observing time of killing mites. Physiological saline and Radix Stemonae extraction were selected as blank control and positive control, respectively.
  
  
  RESULTS
  The TCMs with average time of killing mites below 5 min were Cortex Phellodendri; Herba Taraxac, Herba Agrimoniae, Semen Hydnocarpi, Pericarpium Citri Reticulatae, Rhizoma Dioscoreae Hypoglaucae, Flos Genkwa and Radix Stemona. Among them, time with Cortex phellodendri, Herba Taraxac, Herba Agrimoniae, Semen Hydnocarpi and Pericarpium Citri Reticulatae was statistically shorter than that with Radix Stemonae (P < 0.05).
  
  
  CONCLUSIONS
  Cortex Phellodendri, Herba Taraxac and Herba Agrimoniae et al. had remarkable anti-mite activities to Demodex folliculorum.
authors.affiliation: School of Medicine, Anhui University of Science and Technology, Huainan 232001, China. yetian001@126.com
authors.forename: Ye
authors.initials: Y
authors.lastname: Tian
authors.forename: Chao-pin
authors.initials: CP
authors.lastname: Li
mesh_terms: D000818:Animals; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification / Q000494:pharmacology*; D018859:Hair Follicle / Q000469:parasitology; D006801:Humans; D007306:Insecticides / Q000494:pharmacology*; D008924:Mite Infestations / Q000469:parasitology*; D008925:Mites / Q000187:drug effects*; D010946:Plants, Medicinal / Q000737:chemistry*; D012867:Skin / Q000469:parasitology; D013995:Time
chemical_list: D004365:Drugs, Chinese Herbal; D007306:Insecticides