title: [Diagnosis the state of the proximal renal tubular epithelium in patients with coronary heart disease and chronic heart failure].
abstract: Renal dysfunction is a common complication of chronic heart failure (CHF). Renal filtration capacity has been evaluated in numerous studies, but there are studies dealing with renal tubular function in patients with coronary heart disease (CHD) concurrent with CHF, which became the subject of the present study. Seventy-nine patients with CHD with different stages of CHF (OCCH, 2002) and 12 healthy individuals were examined. The urinary activity of neutral maltase and L-alanine aminopeptidase was evaluated. The renal tubular dysfunction evaluated by the blood levels on the enzymes was found to increase with the greater severity of CHF.
authors.forename: V Iu
authors.initials: VIu
authors.lastname: Kopylov
authors.forename: P Iu
authors.initials: PIu
authors.lastname: Galin
mesh_terms: D000328:Adult; D000368:Aged; D018826:CD13 Antigens / Q000652:urine*; D002908:Chronic Disease; D003327:Coronary Disease / Q000150:complications / Q000175:diagnosis / Q000503:physiopathology / Q000652:urine*; D003937:Diagnosis, Differential; D004848:Epithelium / Q000378:metabolism / Q000503:physiopathology; D006333:Heart Failure / Q000150:complications / Q000175:diagnosis / Q000503:physiopathology / Q000652:urine*; D006801:Humans; D007674:Kidney Diseases / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology / Q000652:urine*; D007677:Kidney Function Tests / Q000379:methods; D007687:Kidney Tubules, Proximal / Q000378:metabolism* / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D000520:alpha-Glucosidases / Q000652:urine*
chemical_list: D000520:alpha-Glucosidases; D018826:CD13 Antigens