[The results of application of magnesium-bearing medications and different load doses of vitamins B1 and B2 in volunteers].
Presently is no consensus of opinion of the size of human optimal daily allowance as for thiamine and riboflavin, so for magnesium, what their content in polyvitamin and mineral preparations testify to. The study was conducted in 60 volunteers, who once took oral dosing of magnesium -bearing preparation "Magnerot" (500 mg of magnesium orotat converting to Mg2+ 32,8 Mg) and "Centrum" (100 mg of magnesium oxide converting to Mg2+ - 60,3 Vg) or vitamins B1 and B2 in 10, 20 and 30 mg doses. The received data testify that during the application of both of these preparations, equal concentration of this element takes place, though in case of magnesium oxide it happens later. As for the used vitamin B1 and B2 doses, it is determined that 10 mg is the optimal dose for treating their hypoavitaminosis.
Koniukhova
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Shikh
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Krasnykh
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D000328:Adult; D001361:Avitaminosis / Q000188:drug therapy* / Q000378:metabolism; D004305:Dose-Response Relationship, Drug; D005260:Female; D006801:Humans; D008277:Magnesium Oxide / Q000008:administration & dosage* / Q000493:pharmacokinetics; D008297:Male; D009963:Orotic Acid / Q000008:administration & dosage / Q000493:pharmacokinetics*; D012256:Riboflavin / Q000008:administration & dosage / Q000493:pharmacokinetics*; D013831:Thiamine / Q000008:administration & dosage / Q000493:pharmacokinetics*; D014803:Vitamin B Complex / Q000008:administration & dosage / Q000493:pharmacokinetics*
D014803:Vitamin B Complex; D008277:Magnesium Oxide; D009963:Orotic Acid; D012256:Riboflavin; D013831:Thiamine