Membraneous glomerulonephritis and non-Hodgkin's lymphoma in a patient with primary Sjögren's syndrome.
The most common renal manifestation of Sjögren's syndrome is tubulointerstitial nephritis, and glomerular disease is rare (3). A 62-year-old woman with primary Sjögren's syndrome developed nephrotic syndrome. Kidney biopsy was consistent with membraneous glomerulonephritis. Steroid pulse therapy was not effective. Three months later she was diagnosed with non-Hodgkin's lymphoma of the tongue, and she was given CHOP therapy and radiation. Both the lymphoma and membraneous glomerulonephritis were resolved.
Iwanaga
Nozomi
N
First Department of Internal Medicine, Graduate School of Biomedical Sciences, Nagasaki, University, Nagasaki, Japan. nozomi0620@yahoo.co.jp
Kamachi
Makoto
M
Fujikawa
Keita
K
Aramaki
Toshiyuki
T
Izumi
Yasumori
Y
Arima
Kazuhiko
K
Tamai
Mami
M
Aratake
Kouichiro
K
Nakamura
Hideki
H
Origuchi
Tomoki
T
Ida
Hiroaki
H
Kawakami
Atsushi
A
Taguchi
Takashi
T
Eguchi
Katsumi
K
D001707:Biopsy, Needle; D003131:Combined Modality Therapy; D005260:Female; D005500:Follow-Up Studies; D015433:Glomerulonephritis, Membranous / Q000150:complications / Q000175:diagnosis* / Q000628:therapy; D006801:Humans; D007150:Immunohistochemistry; D007677:Kidney Function Tests; D008228:Lymphoma, Non-Hodgkin / Q000150:complications / Q000175:diagnosis* / Q000628:therapy; D008875:Middle Aged; D010257:Paraneoplastic Syndromes / Q000150:complications / Q000175:diagnosis* / Q000628:therapy; D035583:Rare Diseases; D012720:Severity of Illness Index; D012859:Sjogren's Syndrome / Q000150:complications / Q000175:diagnosis* / Q000628:therapy; D016896:Treatment Outcome; D016482:Urinalysis