Use of molecular epidemiology to confirm a multistate outbreak of hepatitis A caused by consumption of oysters.
The 39 oyster consumption-related cases of hepatitis A reported in 2005 represent the first large outbreak of hepatitis A associated with shellfish consumption in the United States in >15 years. This is the first outbreak investigation in which an identical hepatitis A virus sequence was obtained from both the implicated food product and case patients.
Bialek
Stephanie R
SR
Division of Viral Hepatitis, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA. sbialek@cdc.gov
George
Prethiba A
PA
Xia
Guo-Liang
GL
Glatzer
Marc B
MB
Motes
Miles L
ML
Veazey
John E
JE
Hammond
Roberta M
RM
Jones
Timothy
T
Shieh
Y Carol
YC
Wamnes
Janet
J
Vaughan
Gilberto
G
Khudyakov
Yury
Y
Fiore
Anthony E
AE
D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000368:Aged; D000818:Animals; D016022:Case-Control Studies; D016001:Confidence Intervals; D004196:Disease Outbreaks; D005260:Female; D005506:Food Contamination / Q000032:analysis / Q000706:statistics & numerical data*; D006506:Hepatitis A / Q000175:diagnosis / Q000453:epidemiology* / Q000821:virology; D030041:Hepatitis A virus / Q000235:genetics / Q000302:isolation & purification*; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D017720:Molecular Epidemiology; D016017:Odds Ratio; D010125:Ostreidae / Q000821:virology*; D016133:Polymerase Chain Reaction; D012367:RNA, Viral / Q000032:analysis; D018570:Risk Assessment; D017678:Sex Distribution
D012367:RNA, Viral