Got sulfate? Luring axons this way and that.
Glycosaminoglycans are sulfated in complex and changing patterns that affect neural development. These sugars mediate interactions between macromolecules, and their biological contributions are of high interest. In this issue of Chemistry & Biology, Shipp and Hsieh-Wilson describe microarrays to probe these complex modifications.
Schwartz
Nancy B
NB
Department of Pediatrics, The University of Chicago, Chicago, IL 60637, USA. n-schwartz@uchicago.edu
Cortes
Mauricio
M
King
Leslie A
LA
D000818:Animals; D001369:Axons / Q000378:metabolism*; D006025:Glycosaminoglycans / Q000378:metabolism*; D051379:Mice; D046228:Microarray Analysis / Q000379:methods; D013431:Sulfates / Q000378:metabolism*
D006025:Glycosaminoglycans; D013431:Sulfates