title: Clinical, electrophysiological and brain imaging features during recurrent ictal cortical blindness associated with chronic liver failure.
abstract: Transient neuroimaging features indicating primary cortical and secondary subcortical white matter cytotoxic oedema have been described in association with prolonged or intense seizures. We describe the unusual condition of recurrent ictal cortical blindness due to focal occipital status epilepticus, in the context of chronic hepatic failure. There was a close association between the onset and disappearance of clinical, electrophysiological and magnetic resonance imaging abnormalities.
authors.affiliation: Department of Neurology, Université catholique de Louvain, Cliniques Universitaires Saint-Luc, Brussels, Belgium. vincent.vanpesch@skynet.be
authors.forename: V
authors.initials: V
authors.lastname: van Pesch
authors.forename: D
authors.initials: D
authors.lastname: Hernalsteen
authors.forename: K
authors.initials: K
authors.lastname: van Rijckevorsel
authors.forename: Th
authors.initials: T
authors.lastname: Duprez
authors.forename: A
authors.initials: A
authors.lastname: Boschi
authors.forename: A
authors.initials: A
authors.lastname: Ivanoiu
authors.forename: C J M
authors.initials: CJ
authors.lastname: Sindic
mesh_terms: D000927:Anticonvulsants / Q000627:therapeutic use; D019575:Blindness, Cortical / Q000188:drug therapy / Q000209:etiology* / Q000503:physiopathology; D001929:Brain Edema / Q000188:drug therapy / Q000209:etiology / Q000503:physiopathology; D002908:Chronic Disease; D004569:Electroencephalography; D017809:Fatal Outcome; D005260:Female; D006501:Hepatic Encephalopathy / Q000150:complications* / Q000503:physiopathology; D006801:Humans; D017093:Liver Failure / Q000150:complications*; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D012008:Recurrence; D013226:Status Epilepticus / Q000150:complications* / Q000188:drug therapy / Q000503:physiopathology; D014793:Visual Cortex / Q000187:drug effects / Q000503:physiopathology
chemical_list: D000927:Anticonvulsants