Estimating choroidal melanoma volume: comparison of methods.
OBJECTIVE
To evaluate published methods of estimating choroidal melanoma volume.


METHODS
Prospective consecutive case series.


METHODS
Ten consecutive patients with primary choroidal melanoma.


METHODS
After determination of tumor dimensions (largest tumor basal diameter, basal perpendicular diameter, and height), tumor volume was calculated for each tumor by using the 5 published methods. Percent differences in tumor volume were determined for each tumor as calculated by different methods.


METHODS
Choroidal melanoma volume.


RESULTS
The mean variation in estimated tumor volume expressed as a ratio was 2.33 (range, 1.64-3.84).


CONCLUSIONS
Choroidal melanoma volume calculation methods are inconsistent and caution is needed when volume measures are used for prognostic classification.
Singh
Arun D
AD
Department of Ophthalmic Oncology, Cole Eye Institute, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA. singha@ccf.org
Terman
Sam
S
Sculley
LuAnne
L
D002830:Choroid Neoplasms / Q000473:pathology*; D003941:Diagnostic Techniques, Ophthalmological; D006801:Humans; D008545:Melanoma / Q000473:pathology*; D008962:Models, Theoretical; D011446:Prospective Studies