title: [Comparative study of two preservation solutions in the initial function after bilateral human lung transplantation].
abstract: OBJECTIVE
  Compare the influence of two preservation liquids, Euro-Collins (EC) and Perfadex (P) in the pulmonary graft function in the initial phase of lung transplant in humans.
  
  
  METHODS
  Retrospective study.
  
  
  METHODS
  Lung transplant unit of the ICU of a university hospital.
  
  
  METHODS
  A total of 79 patients were subjected to a transplant of both lungs. The pulmonary grafts were preserved with EC in 23 cases and with P in 56 cases.
  
  
  METHODS
  Pulmonary function was assessed on admission in the intensive care unit (ICU) with the PaO2/FiO2 ratio. Mortality, graft dysfunction stay in ICU and time of mechanical ventilation were also assessed at 30 days.
  
  
  RESULTS
  The PaO2/FiO2 ratio was significantly greater in the P group than in the EC both on admission (p<0.006) and at 12 hours (p=0.032) in the ICU. Graft dysfunction incidence was less in group P than in EC (p<0.045). There were no differences in regards to mortality at 30 days, stay in ICU and time of mechanical ventilation between both groups.
  
  
  CONCLUSIONS
  Preservation of the pulmonary graft with P as preservation liquid compared with EC is associated with better graft function in the initial phases of transplant of both lungs and with a decrease in the incidence of graft dysfunction.
authors.affiliation: Servicio de Medicina Intensiva, Hospital Universitario Marqués de Valdecilla, Santander, España. eminambres@yahoo.es
authors.forename: E
authors.initials: E
authors.lastname: Miñambres
authors.forename: A
authors.initials: A
authors.lastname: González-Castro
authors.forename: J M
authors.initials: JM
authors.lastname: Rabanal
authors.forename: B
authors.initials: B
authors.lastname: Suberviola
authors.forename: F J
authors.initials: FJ
authors.lastname: Ortega
authors.forename: F
authors.initials: F
authors.lastname: Zurbano
authors.forename: G
authors.initials: G
authors.lastname: Díaz-Regañón
authors.forename: J
authors.initials: J
authors.lastname: Llorca
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D016040:Lung Transplantation / Q000379:methods / Q000502:physiology*; D008297:Male; D008875:Middle Aged; D019188:Organ Preservation Solutions; D012189:Retrospective Studies
chemical_list: D019188:Organ Preservation Solutions