Mutagenic, antimutagenic and antioxidant activities of a new class of beta-glucoside hydroxyhydroquinone from Anagallis monelli growing in Tunisia.
A new skeleton of an O-heteroside natural substance named zinolol, the first representative of a new class of aminated hydroxyhydroquinone, has been isolated from the whole plant Anagallis monelli. Its structure has been established by one and two dimensional NMR spectroscopic procedures. Antioxidant, mutagenic, antimutagenic activities were realised and positive results were recorded.
Ammar
Samia
S
Laboratoire de Chimie des Substances Naturelles et de Synthèse Organique 99/UR/12-26, Faculté des Sciences de Monastir, Monastir, Tunisie.
Mahjoub
Mohamed Ali
MA
Charfi
Nesrine
N
Skandarani
Ines
I
Chekir-Ghedira
Leila
L
Mighri
Zine
Z
D031823:Anagallis / Q000737:chemistry*; D000975:Antioxidants / Q000737:chemistry / Q000494:pharmacology; D001713:Biphenyl Compounds / Q000737:chemistry; D004926:Escherichia coli / Q000187:drug effects / Q000235:genetics; D016166:Free Radical Scavengers / Q000737:chemistry / Q000494:pharmacology; D005960:Glucosides / Q000737:chemistry* / Q000494:pharmacology*; D006834:Hydrazines / Q000737:chemistry; D006873:Hydroquinones / Q000737:chemistry* / Q000494:pharmacology*; D015394:Molecular Structure; D009152:Mutagenicity Tests; D010851:Picrates; D014416:Tunisia
D000975:Antioxidants; D001713:Biphenyl Compounds; D016166:Free Radical Scavengers; D005960:Glucosides; D006834:Hydrazines; D006873:Hydroquinones; D010851:Picrates; C520692:zinolol; C013038:hydroxyhydroquinone; C004931:1,1-diphenyl-2-picrylhydrazyl