title: [Orbital involvement in IgD Kappa myeloma].
abstract: BACKGROUND
  IgDkappa myeloma accounts for less than 2% of all myeloma cases. Orbital involvement is uncommon in myeloma and the authors suggest a possible predilection for IgD myeloma to involve the orbit.
  
  
  METHODS
  A 67-year-old women was admitted for diffuse bone pain and painful ptosis of the right eye. The symptoms had progressed over approximately 1 year and were associated with a severe decline in general health. The biochemical, hematological, and radiological investigations suggested the diagnosis of an IgD kappa myeloma. Orbital x-ray showed destruction of the greater and lesser right wing of the sphenoid bone. Treatment was polychemotherapy. The course of the disease was very rapid and death occurred within 17 months from renal failure and amyloidosis.
  
  
  CONCLUSIONS
  Orbital involvement by myeloma occurs in 0.3% of cases and the majority are unilateral. The typical orbital symptoms include ptosis, diplopia, loss of vision, and pain. This was not considered to contribute to poor prognosis but may affect the functional prognosis.
authors.affiliation: Service de Médecine Interne, Hôpital Militaire Moulay Ismail, Meknès, Morocco. hassikouhasna@hotmail.com
authors.forename: H
authors.initials: H
authors.lastname: Hassikou
authors.forename: F
authors.initials: F
authors.lastname: Tabache
authors.forename: S
authors.initials: S
authors.lastname: Safi
authors.forename: A
authors.initials: A
authors.lastname: Laktaoui
authors.forename: L
authors.initials: L
authors.lastname: Hadri
mesh_terms: D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D005128:Eye Diseases / Q000453:epidemiology / Q000209:etiology*; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007072:Immunoglobulin D / Q000097:blood*; D007145:Immunoglobulin kappa-Chains / Q000097:blood*; D009101:Multiple Myeloma / Q000150:complications* / Q000276:immunology*; D012886:Skull / Q000473:pathology
chemical_list: D007072:Immunoglobulin D; D007145:Immunoglobulin kappa-Chains