title: Maxillary sinus floor augmentation using autogenous bone grafts and platelet-enriched fibrin glue with simultaneous implant placement.
abstract: OBJECTIVE
  The aim of this study was to evaluate the use of autogenous bone in combination with platelet-enriched fibrin glue as a grafting material for maxillary sinus augmentation with simultaneous implant placement in dogs.
  
  
  METHODS
  The mucous membranes of 12 sinuses in 6 dogs were elevated bilaterally. In the right sinus, autogenous bone mixed with platelet-enriched fibrin glue was grafted into the space between the membrane and the sinus wall. In the left sinus, autogenous bone alone was grafted as a control. At the same time, 2 dental implants were inserted into the grafting material through the maxillary sinus floor. The animals were killed 6 months after surgery.
  
  
  RESULTS
  The mean bone-implant contact was 40.5% on the fibrin glue side and 32.3% on the control side (P < .05). The mean height of newly formed bone in the augmented area was 12.2 mm on the fibrin glue side and 10.7 mm on the control side (P < .05).
  
  
  CONCLUSIONS
  The results indicate that the use of autogenous bone mixed with platelet-enriched fibrin glue can achieve results superior to those for grafts of autogenous bone alone. The specific improvements of this technique include enhanced osseointegration of dental implants and increased height of new bone.
authors.affiliation: Department of Oral and Maxillofacial Surgery, College of Dentistry, Yonsei University, Seoul, South Korea.
authors.forename: Hyeon-Jung
authors.initials: HJ
authors.lastname: Lee
authors.forename: Byung-Ho
authors.initials: BH
authors.lastname: Choi
authors.forename: Jae-Hyung
authors.initials: JH
authors.lastname: Jung
authors.forename: Shi-Jiang
authors.initials: SJ
authors.lastname: Zhu
authors.forename: Seoung-Ho
authors.initials: SH
authors.lastname: Lee
authors.forename: Jin-Young
authors.initials: JY
authors.lastname: Huh
authors.forename: Tae-Min
authors.initials: TM
authors.lastname: You
authors.forename: Jingxu
authors.initials: J
authors.lastname: Li
mesh_terms: D000818:Animals; D001861:Bone Regeneration / Q000187:drug effects*; D016025:Bone Transplantation / Q000379:methods*; D003758:Dental Implantation, Endosseous; D004285:Dogs; D005260:Female; D015718:Fibrin Tissue Adhesive / Q000494:pharmacology*; D008443:Maxillary Sinus / Q000601:surgery*; D023421:Models, Animal; D013516:Oral Surgical Procedures, Preprosthetic / Q000379:methods*; D053657:Platelet-Rich Plasma; D018709:Statistics, Nonparametric
chemical_list: D015718:Fibrin Tissue Adhesive