title: A parallel tracking method for acoustic radiation force impulse imaging.
abstract: Radiation force-based techniques have been developed by several groups for imaging the mechanical properties of tissue. Acoustic Radiation Force Impulse (ARFI) imaging is one such method that uses commercially available scanners to generate localized radiation forces in tissue. The response of the tissue to the radiation force is determined using conventional B-mode imaging pulses to track micron-scale displacements in tissue. Current research in ARFI imaging is focused on producing real-time images of tissue displacements and related mechanical properties. Obstacles to producing a real-time ARFI imaging modality include data acquisition, processing power, data transfer rates, heating of the transducer, and patient safety concerns. We propose a parallel receive beamforming technique to reduce transducer heating and patient acoustic exposure, and to facilitate data acquisition for real-time ARFI imaging. Custom beam sequencing was used with a commercially available scanner to track tissue displacements with parallel-receive beamforming in tissue-mimicking phantoms. Using simulations, the effects of material properties on parallel tracking are observed. Transducer and tissue heating for parallel tracking are compared to standard ARFI beam sequencing. The effects of tracking beam position and size of the tracked region are also discussed in relation to the size and temporal response of the region of applied force, and the impact on ARFI image contrast and signal-to-noise ratio are quantified.
authors.affiliation: Duke University, Department of Biomedical Engineering, Durham, NC, USA. jjd@duke.edu
authors.forename: Jeremy J
authors.initials: JJ
authors.lastname: Dahl
authors.forename: Gianmarco F
authors.initials: GF
authors.lastname: Pinton
authors.forename: Mark L
authors.initials: ML
authors.lastname: Palmeri
authors.forename: Vineet
authors.initials: V
authors.lastname: Agrawal
authors.forename: Kathryn R
authors.initials: KR
authors.lastname: Nightingale
authors.forename: Gregg E
authors.initials: GE
authors.lastname: Trahey
mesh_terms: D000465:Algorithms; D003198:Computer Simulation; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D008954:Models, Biological; D009068:Movement / Q000502:physiology; D019047:Phantoms, Imaging; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013314:Stress, Mechanical; D014463:Ultrasonography / Q000379:methods*