Epigenetics: a landscape takes shape.
Epigenetics has recently evolved from a collection of diverse phenomena to a defined and far-reaching field of study. In this Essay, we examine the epistemology of epigenetics, provide a brief overview of underlying molecular mechanisms, and suggest future challenges for the field.
Goldberg
Aaron D
AD
Laboratory of Chromatin Biology, The Rockefeller University, New York, NY 10021, USA.
Allis
C David
CD
Bernstein
Emily
E
D000818:Animals; D002454:Cell Differentiation / Q000235:genetics*; D002455:Cell Division / Q000235:genetics*; D042002:Chromatin Assembly and Disassembly / Q000235:genetics; D019175:DNA Methylation; D044127:Epigenesis, Genetic / Q000235:genetics*; D005786:Gene Expression Regulation / Q000235:genetics*; D006657:Histones / Q000235:genetics / Q000378:metabolism; D006801:Humans; D022661:RNA, Untranslated / Q000235:genetics
D006657:Histones; D022661:RNA, Untranslated