title: Emerging cystic fibrosis pathogens: incidence and antimicrobial resistance.
abstract: We examined the frequency of isolation and the antimicrobial resistance of Burkholderia cepacia complex, Stenotrophomonas maltophilia and Achromobacter xylosoxidans in cystic fibrosis patients from 2000 to 2004. Strains susceptibility to tobramycin, piperacillin/tazobactam, imipenem, gentamicin, ciprofloxacin and ceftazidime was determined by disc diffusion assay. B. cepacia complex showed a very high resistance also to ciprofloxacin reaching 100% in 2004. S. maltophilia and A. xvylosoxidans showed high rates of antimicrobial resistance both aminoglycoside and ciprofloxacin. It is very important to monitor the percentage of isolation of these species over time to verify strains resistance to antibiotics and also to test new combinations of antimicrobial agents.
authors.affiliation: Department of Public health Sciences, La Sapienza University of Rome, Italy.
authors.forename: Annarita
authors.initials: A
authors.lastname: Magni
authors.forename: Alessandra
authors.initials: A
authors.lastname: Giordano
authors.forename: Carlo
authors.initials: C
authors.lastname: Mancini
authors.forename: Claudia
authors.initials: C
authors.lastname: Pecoraro
authors.forename: Paola
authors.initials: P
authors.lastname: Varesi
authors.forename: Serena
authors.initials: S
authors.lastname: Quattrucci
authors.forename: Maria
authors.initials: M
authors.lastname: Trancassini
mesh_terms: D042402:Achromobacter / Q000187:drug effects; D000293:Adolescent; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D042602:Burkholderia cepacia complex / Q000187:drug effects; D003550:Cystic Fibrosis / Q000453:epidemiology / Q000382:microbiology*; D024881:Drug Resistance, Bacterial; D016905:Gram-Negative Bacterial Infections / Q000453:epidemiology* / Q000382:microbiology; D006801:Humans; D015994:Incidence; D007558:Italy / Q000453:epidemiology; D008826:Microbial Sensitivity Tests; D044166:Xanthomonadaceae / Q000187:drug effects
chemical_list: D000900:Anti-Bacterial Agents