title: A review of metabolic consequences and long-term complications of enterocystoplasty in children.
abstract: This review summarizes the important metabolic consequences and long-term complications associated with enterocystoplasty, with a particular emphasis on the pediatric patient with genitourinary abnormalities. A directed Medline literature review for metabolic and long-term complications following enterocystoplasty was performed. Information gained through published literature and from our database was reviewed and summarized to provide the reader with a thorough review of the subject. Bowel is not a perfect tissue for substitution or augmentation, and its use to treat functionally and structurally compromised bladders is associated with several metabolic consequences and long-term complications. Metabolic acidosis is the most common metabolic abnormality seen. The rates and severity of these complications vary, though they may have a profound impact on a patient's quality of life after enterocystoplasty. The metabolic consequences and long-term complications associated with enterocystoplasty are important clinical features of this intervention, and careful consideration should be given to them before pursuing enterocystoplasty.
authors.affiliation: Division of Pediatric Urology, Children's Hospital of New York, 3959 Broadway, 219 N., New York, NY 10032, USA. twhenslemd@aol.com
authors.forename: Terry W
authors.initials: TW
authors.lastname: Hensle
authors.forename: Scott M
authors.initials: SM
authors.lastname: Gilbert
mesh_terms: D000714:Anastomosis, Surgical / Q000009:adverse effects / Q000379:methods; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007420:Intestine, Large / Q000601:surgery; D007421:Intestine, Small / Q000601:surgery; D008297:Male; D008659:Metabolic Diseases / Q000209:etiology* / Q000503:physiopathology; D011183:Postoperative Complications; D011379:Prognosis; D011788:Quality of Life; D019651:Plastic Surgery Procedures / Q000009:adverse effects / Q000379:methods; D013270:Stomach / Q000601:surgery; D001743:Urinary Bladder / Q000002:abnormalities* / Q000601:surgery*; D014547:Urinary Diversion / Q000009:adverse effects* / Q000379:methods; D016476:Urinary Reservoirs, Continent / Q000009:adverse effects*; D014564:Urogenital Abnormalities / Q000175:diagnosis / Q000601:surgery