Successful steroid treatment for fibrosing mediastinitis and sclerosing cervicitis.
The use of steroids to successfully treat a 75-year-old woman with fibrosing mediastinitis and sclerosing cervicitis causing a stricture of the left common carotid artery is reported. Biopsy specimens showed collagenous fibers and fibroblasts with moderate infiltration of lymphocytes. The mediastinal and neck lesions were significantly reduced, with almost complete resolution of arterial stricture, 3 months after initiating administration of prednisolone at 20 mg/d.
Ikeda
Koei
K
Department of Thoracic Surgery, Graduate School of Medicine, Kumamoto University, Kumamoto, Japan.
Nomori
Hiroaki
H
Mori
Takeshi
T
Kobayashi
Hironori
H
Iwatani
Kazunori
K
Yoshimoto
Kentaro
K
Yoshioka
Masakazu
M
D000368:Aged; D002340:Carotid Artery Diseases / Q000209:etiology; D017536:Carotid Artery, Common; D003251:Constriction, Pathologic; D005260:Female; D005355:Fibrosis; D005938:Glucocorticoids / Q000627:therapeutic use*; D006801:Humans; D008480:Mediastinitis / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy* / Q000473:pathology*; D049268:Positron-Emission Tomography; D011239:Prednisolone / Q000627:therapeutic use*; D013902:Radiography, Thoracic; D012598:Sclerosis; D016896:Treatment Outcome; D002575:Uterine Cervicitis / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy* / Q000473:pathology*
D005938:Glucocorticoids; D011239:Prednisolone