title: A diagnostic trap for the dermatopathologist: granulomatous reactions from cutaneous microimplants for cosmetic purposes.
abstract: We present a case of late granulomatous reactions from silicone that first appeared in a site different from that of the injection causing an incorrect diagnosis of liposarcoma in the beginning. The histological picture was a cystic-macrophagic granuloma in both the injection site (upper lip) and the migrating site (paranasal regions). We think that the foreign body has undergone an antigravity migration from the upper lip to the right paranasal region. To our knowledge, such a phenomenon has not been yet reported in literature.
authors.affiliation: Department of Dermatology, CIVICO Hospital, Via Carmelo Lazzaro, Palermo, Italy. v.mustacchio@virgilio.it
authors.forename: Vincenzo
authors.initials: V
authors.lastname: Mustacchio
authors.forename: D
authors.initials: D
authors.lastname: Cabibi
authors.forename: M I
authors.initials: MI
authors.lastname: Minervini
authors.forename: E
authors.initials: E
authors.lastname: Barresi
authors.forename: S
authors.initials: S
authors.lastname: Amato
mesh_terms: D015415:Biomarkers / Q000378:metabolism; D003357:Cosmetic Techniques / Q000009:adverse effects*; D003880:Dermatology / Q000379:methods; D005145:Face / Q000473:pathology; D005260:Female; D015745:Granuloma, Foreign-Body / Q000175:diagnosis* / Q000209:etiology* / Q000378:metabolism; D006801:Humans; D007150:Immunohistochemistry; D007279:Injections, Subcutaneous; D008875:Middle Aged; D010340:Pathology, Surgical / Q000379:methods; D019736:Prostheses and Implants / Q000009:adverse effects*; D012828:Silicones / Q000009:adverse effects*; D012867:Skin / Q000378:metabolism / Q000473:pathology
chemical_list: D015415:Biomarkers; D012828:Silicones