title: The Calyptogena magnifica chemoautotrophic symbiont genome.
abstract: Chemoautotrophic endosymbionts are the metabolic cornerstone of hydrothermal vent communities, providing invertebrate hosts with nearly all of their nutrition. The Calyptogena magnifica (Bivalvia: Vesicomyidae) symbiont, Candidatus Ruthia magnifica, is the first intracellular sulfur-oxidizing endosymbiont to have its genome sequenced, revealing a suite of metabolic capabilities. The genome encodes major chemoautotrophic pathways as well as pathways for biosynthesis of vitamins, cofactors, and all 20 amino acids required by the clam.
authors.affiliation: Harvard University, 16 Divinity Avenue, Biolabs 4080, Cambridge, MA 02138, USA.
authors.forename: I L G
authors.initials: IL
authors.lastname: Newton
authors.forename: T
authors.initials: T
authors.lastname: Woyke
authors.forename: T A
authors.initials: TA
authors.lastname: Auchtung
authors.forename: G F
authors.initials: GF
authors.lastname: Dilly
authors.forename: R J
authors.initials: RJ
authors.lastname: Dutton
authors.forename: M C
authors.initials: MC
authors.lastname: Fisher
authors.forename: K M
authors.initials: KM
authors.lastname: Fontanez
authors.forename: E
authors.initials: E
authors.lastname: Lau
authors.forename: F J
authors.initials: FJ
authors.lastname: Stewart
authors.forename: P M
authors.initials: PM
authors.lastname: Richardson
authors.forename: K W
authors.initials: KW
authors.lastname: Barry
authors.forename: E
authors.initials: E
authors.lastname: Saunders
authors.forename: J C
authors.initials: JC
authors.lastname: Detter
authors.forename: D
authors.initials: D
authors.lastname: Wu
authors.forename: J A
authors.initials: JA
authors.lastname: Eisen
authors.forename: C M
authors.initials: CM
authors.lastname: Cavanaugh
mesh_terms: D000818:Animals; D049872:Bivalvia / Q000382:microbiology*; D002244:Carbon / Q000378:metabolism; D052837:Chemoautotrophic Growth; D020563:Gammaproteobacteria / Q000235:genetics* / Q000302:isolation & purification / Q000378:metabolism / Q000648:ultrastructure; D016680:Genome, Bacterial; D008969:Molecular Sequence Data; D010788:Photosynthesis; D013559:Symbiosis
chemical_list: D002244:Carbon