title: Isolated extramedullary relapse in the breast of a patient with acute myeloid leukemia following allogeneic stem cell transplantation: case report and review of the literature.
abstract: We report an unsual case of a woman with acute myeloid leukemia who showed an isolated extramedullary relapse (IEMR) in the breast following allogeneic stem cell transplantation and review the related literature. Eighty cases of IEMR following allogeneic stem cell transplantation, including our case, were identified. The review suggests that an M2 or M4 phenotype in the French-American-British classification and a favorable cytogenetic risk group are more frequently associated with the occurrence of IEMR. Combined treatment with radiation and high-dose chemotherapy may be effective.
authors.affiliation: Centre National de Greffe de Moelle Osseuse, Tunis, Tunisia. aabdelkefi@yahoo.fr
authors.forename: Abderrahman
authors.initials: A
authors.lastname: Abdelkefi
authors.forename: Lamia
authors.initials: L
authors.lastname: Torjman
authors.forename: Saloua
authors.initials: S
authors.lastname: Ladeb
authors.forename: Zeineb
authors.initials: Z
authors.lastname: Sghaïer
authors.forename: Ramzi
authors.initials: R
authors.lastname: Jeddi
authors.forename: Amel
authors.initials: A
authors.lastname: Lakhal
authors.forename: Amr
authors.initials: A
authors.lastname: Ramzu
authors.forename: Amor
authors.initials: A
authors.lastname: Gamoudi
authors.forename: Tarek Ben
authors.initials: TB
authors.lastname: Othman
mesh_terms: D000328:Adult; D001943:Breast Neoplasms / Q000188:drug therapy; D003131:Combined Modality Therapy; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000188:drug therapy; D008297:Male; D012008:Recurrence; D033581:Stem Cell Transplantation; D014184:Transplantation, Homologous