Toxic neuropathies associated with pharmaceutic and industrial agents.
Neuropathies associated with industrial, environmental, and pharmacologic toxicants are uncommon. Nevertheless, it is important to consider toxic etiologies in the differential diagnosis of neuropathies, because they are among the most treatable forms of peripheral nervous system dysfunction. The purpose of this article is to discuss the clinical investigation of a suspected toxic neuropathy, to review some of the more common or representative neurotoxicants, and to identify the methods for establishing causation.
London
Zachary
Z
Department of Neurology, University of Michigan, 1324 Taubman Center, Ann Arbor, MI 48109-0322, USA.
Albers
James W
JW
D000638:Amiodarone / Q000009:adverse effects; D000970:Antineoplastic Agents / Q000009:adverse effects; D001151:Arsenic / Q000009:adverse effects; D064420:Drug-Related Side Effects and Adverse Reactions; D015386:Hazardous Substances / Q000009:adverse effects*; D006801:Humans; D007221:Industry; D009431:Neural Conduction / Q000187:drug effects; D010755:Organophosphates / Q000009:adverse effects; D010523:Peripheral Nervous System Diseases / Q000139:chemically induced*; D013793:Thallium / Q000009:adverse effects; D014665:Vasodilator Agents / Q000009:adverse effects; D014750:Vincristine / Q000009:adverse effects; D014805:Vitamin B 12 / Q000009:adverse effects
D000970:Antineoplastic Agents; D015386:Hazardous Substances; D010755:Organophosphates; D014665:Vasodilator Agents; D014750:Vincristine; D013793:Thallium; D000638:Amiodarone; D001151:Arsenic; D014805:Vitamin B 12