title: Primary sclerosing cholangitis and uveitis: a case series.
abstract: OBJECTIVE
  To report the cases of six patients with primary sclerosing cholangitis and uveitis.
  
  
  METHODS
  Retrospective observational case series.
  
  
  METHODS
  Two index cases were identified from the Uveitis Clinic of the Casey Eye Institute, Oregon Health and Science University and another from the Portland area. Additional cases were identified through a web-based survey of members of the American Uveitis Society.
  
  
  RESULTS
  Three males and three females were identified. Five of six patients were diagnosed with uveitis prior to primary sclerosing cholangitis. Four had unilateral eye involvement. Five had insidious onset. All had persistent duration. Clinical course was chronic for three, recurrent for two, and chronic-recurrent in one. Vitreous inflammation was prominent in five.
  
  
  CONCLUSIONS
  Although the number of patients who were studied is limited, there appears to be an association between primary sclerosing cholangitis and uveitis. Further studies are required to confirm such an association.
authors.affiliation: Casey Eye Institute, Oregon Health and Science University, Portland, Oregon 97239, USA. hoangl@ohsu.edu
authors.forename: Lani T
authors.initials: LT
authors.lastname: Hoang
authors.forename: Lyndell L
authors.initials: LL
authors.lastname: Lim
authors.forename: R Christopher
authors.initials: RC
authors.lastname: Walton
authors.forename: Debra A
authors.initials: DA
authors.lastname: Goldstein
authors.forename: Brent
authors.initials: B
authors.lastname: Chalmers
authors.forename: James T
authors.initials: JT
authors.lastname: Rosenbaum
mesh_terms: D000328:Adult; D015209:Cholangitis, Sclerosing / Q000150:complications* / Q000175:diagnosis; D002908:Chronic Disease; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012008:Recurrence; D012189:Retrospective Studies; D014605:Uveitis / Q000150:complications* / Q000175:diagnosis