title: [Progress in the studies of premature ejaculation].
abstract: Premature ejaculation is a common but incompletely understood male sexual dysfunction. Recent years have witnessed fruitful researches on NO in the mechanism of male ejaculation and successful application of selective PDE5 inhibitor in the treatment of male sexual dysfunction. And now the researches on the etiopathogenesis, mechanism, diagnosis and therapy of premature ejaculation have achieved great development. Selective serotonin re-uptake inhibitors (SSRIs) have been widely applied to clinical practice, but with increasing adverse effects. The purpose of the review is to introduce the updated development of the epidemiology, definition, etiopathogenesis, mechanism and therapy of premature ejaculation, and to provide some reference for the diagnosis and management of the problem.
authors.affiliation: Department of Urology, Nanjing Jinling Andrology Hospital, Nanjing, Jiangsu 210029, China. xuejun7826@126.com
authors.forename: Jun
authors.initials: J
authors.lastname: Xue
authors.forename: Jing-yu
authors.initials: JY
authors.lastname: Wang
authors.forename: Li-sheng
authors.initials: LS
authors.lastname: Chen
authors.forename: Xue-gang
authors.initials: XG
authors.lastname: Ding
mesh_terms: D000328:Adult; D000368:Aged; D004542:Ejaculation; D006801:Humans; D008297:Male; D008875:Middle Aged; D017367:Selective Serotonin Reuptake Inhibitors / Q000627:therapeutic use; D012735:Sexual Dysfunction, Physiological / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology
chemical_list: D017367:Selective Serotonin Reuptake Inhibitors