title: Management of spontaneous rupture of the oesophagus (Boerhaave's syndrome): single centre experience of 18 cases.
abstract: BACKGROUND
  Spontaneous oesophageal rupture (Boerhaave's syndrome) is rare, and carries a high attendant risk of mortality.
  
  
  METHODS
  A retrospective eight-year review from a tertiary unit.
  
  
  RESULTS
  Eighteen patients were managed, with a mean age of 57 (39 - 88 years). Eight patients presented early and underwent surgery, seven with primary closure and one with exclusion and diversion. There was one death in this group. Ten patients were managed conservatively. In this group, two underwent an oesophagectomy because of failed conservative measures, and four had an endoprosthesis inserted. One patient died in this group on the first admission, but two patients with stents in situ died from massive bleeding relating to an aorto-oesophageal fistula at 39 days and 189 days respectively following presentation.
  
  
  CONCLUSIONS
  Surgical intervention remains the gold standard when the diagnosis is made early. For late diagnoses, this series suggests caution in the use of endoprostheses.
authors.affiliation: Dept of Clinical Surgery, St James's Hospital and Trinity College Dublin.
authors.forename: R
authors.initials: R
authors.lastname: Prichard
authors.forename: J
authors.initials: J
authors.lastname: Butt
authors.forename: N
authors.initials: N
authors.lastname: Al-Sariff
authors.forename: S
authors.initials: S
authors.lastname: Frohlich
authors.forename: S
authors.initials: S
authors.lastname: Murphy
authors.forename: B
authors.initials: B
authors.lastname: Manning
authors.forename: N
authors.initials: N
authors.lastname: Ravi
authors.forename: J V
authors.initials: JV
authors.lastname: Reynolds
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D004935:Esophageal Diseases / Q000628:therapy*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012422:Rupture, Spontaneous / Q000628:therapy; D013577:Syndrome