Urgent liver transplantation for acute liver failure due to parvovirus B19 infection complicated by primary Epstein-Barr virus and cytomegalovirus infections and aplastic anaemia.
An 11-year-old boy presented with hepatic failure secondary to parvovirus B19 infection, requiring urgent liver transplantation. His recovery was complicated by primary Epstein-Barr virus and cytomegalovirus infections. He subsequently developed aplastic anaemia that has been refractory to antithymocyte globulin and cyclosporine therapy and may now require bone marrow transplantation. We present this case to emphasize parvovirus as a rare cause of hepatic failure and of aplastic anaemia as a complication of the virus.
So
K
K
Western Australian Liver Transplantation Service, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia. kenji.so@health.wa.gov.au
Macquillan
G
G
Garas
G
G
Delriviere
L
L
Mitchell
A
A
Speers
D
D
Mews
C
C
Augustson
B
B
de Boer
W B
WB
Baker
D
D
Jeffrey
G P
GP
D000741:Anemia, Aplastic / Q000150:complications*; D002648:Child; D003586:Cytomegalovirus Infections / Q000150:complications; D004638:Emergency Treatment; D020031:Epstein-Barr Virus Infections / Q000150:complications; D006801:Humans; D008099:Liver / Q000473:pathology; D017114:Liver Failure, Acute / Q000150:complications* / Q000473:pathology / Q000601:surgery*; D016031:Liver Transplantation; D008297:Male; D010322:Parvoviridae Infections / Q000150:complications; D016732:Parvovirus B19, Human; D014777:Virus Diseases / Q000150:complications*