[Effect of Type 2 Diabetes on Results of Endovascular Treatment of Ischemic Heart Disease With Drug Covered Stents (Results of 1 Year Follow-up).].
Aim of the study was to determine the impact of sirolimus-eluting stents (SES) on clinical outcomes in patients with type 2 diabetes mellitus (DM) undergoing coronary revascularisation. The study enrolled 99 diabetic patients with de novo lesions in native coronary arteries. Medically treated DM was present in 61 patients (62%), 7 (7%) of whom required insulin. 53 patients received 78 SES and 46 patients received 57 bare metal stents. The differences in clinical outcomes between diabetic patients treated with SES and bare metal stents were assessed. Major adverse cardiac events (MACE) defined as death, myocardial infarction (MI), repeat revascularizations, and recurrences of angina were analyzed at 12-month follow-up. In the SES group the rate of recurrence of angina was 17%, the rate of coronary artery bypass surgery was 3,8%, the rate of repeat coronary angioplasty was 5,7%. In the bare metal stent group the rate of recurrence of angina was 37,8%, the rate of coronary artery bypass surgery was 2,2%, the rate of MI was 4,4%, the rate of repeat coronary angioplasty was 22,2%. Implantation of SES in patients with type 2 diabetes mellitus reduces recurrence of angina and major adverse cardiac events during first year after coronary angioplasty.
Petrova
K N
KN
A.L. Myasnikov Institute of Clinical Cardiology; ul. Tretiya Cherepkovskaya, 15a, 121552 Moscow, Russia.
Kozlov
S G
SG
Liakishev
A A
AA
Savchenko
A P
AP
D017023:Coronary Angiography; D023903:Coronary Restenosis; D003924:Diabetes Mellitus, Type 2; D054855:Drug-Eluting Stents; D005500:Follow-Up Studies; D006801:Humans; D020123:Sirolimus; D015607:Stents; D016896:Treatment Outcome
D020123:Sirolimus