title: Report of a hürthle cell neoplasm in a peripubertal girl.
abstract: Thyroid nodules are rare in children compared to adults. Although most thyroid nodules are benign, the risk of malignancy is greater in pediatric patients. Papillary and follicular cell tumors account for the majority of thyroid neoplasms; Hürthle cell tumors account for less than 5%. Despite being uncommon, malignant Hürthle cell tumors are potentially more aggressive than papillary and follicular cell tumors. Therefore, distinguishing between types of thyroid neoplasms in a timely fashion has implications for prognosis and therapy. We describe a 12-year-old peripubertal girl who presented with a large right-sided thyroid nodule that was subsequently diagnosed as a Hürthle cell adenoma. To our knowledge, she represents the youngest patient with a Hürthle cell neoplasm.
authors.affiliation: Department of Pediatrics, University of California, San Francisco, California, USA.
authors.forename: Andrew A
authors.initials: AA
authors.lastname: Bremer
authors.forename: Brian J
authors.initials: BJ
authors.lastname: Feldman
authors.forename: Gioia
authors.initials: G
authors.lastname: Iezza
authors.forename: Orlo H
authors.initials: OH
authors.lastname: Clark
authors.forename: Stephen M
authors.initials: SM
authors.lastname: Rosenthal
mesh_terms: D018249:Adenoma, Oxyphilic / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D002648:Child; D005260:Female; D006801:Humans; D013964:Thyroid Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D016606:Thyroid Nodule / Q000473:pathology