title: In silico biology: from simulation to understanding.
abstract: Mathematical modelling is feasible only if the biological system under consideration meets certain criteria--if they are met, a comprehensive quantitative approach not only yields information about the dynamics of intracellular processes but eventually allows for the prediction of population behaviour from molecular interactions.
authors.affiliation: Institut für Theoretische Biologie, Humboldt-Universität, Invalidenstr. 43, D-10115 Berlin, Germany. m.kollmann@biologie.hu-berlin.de
authors.forename: Markus
authors.initials: M
authors.lastname: Kollmann
authors.forename: Victor
authors.initials: V
authors.lastname: Sourjik
mesh_terms: D002468:Cell Physiological Phenomena; D002633:Chemotaxis / Q000502:physiology*; D019295:Computational Biology / Q000379:methods*; D003198:Computer Simulation; D004926:Escherichia coli; D008962:Models, Theoretical; D015398:Signal Transduction / Q000502:physiology*