Intralesional cisplatin chemotherapy and topical cryotherapy for the control of choanal squamous cell carcinoma in an African penguin (Spheniscus demersus).
A 3.5-yr-old, 2.5-kg female African penguin (Spheniscus demersus) was diagnosed with a choanal squamous cell carcinoma on the basis of biopsy after a history of choanal ulceration and anorexia with weight loss. Therapeutic modalities included the use of intralesional cisplatin followed by localized, topical cryotherapy with liquid nitrogen. The penguin remained free of clinical disease for a period of 9 mo, at which time a second cryotreatment was performed. The patient has remained free of all signs of choanal carcinoma for a period of 13 mo since the second cryotreatment.
Ferrell
Shannon T
ST
Animal Health Department, Fort Worth Zoological Park, 1989 Colonial Parkway, Fort Worth, Texas 76110, USA.
Marlar
Annajane B
AB
Garner
Michael
M
Lung
Nancy P
NP
D000818:Animals; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D001715:Bird Diseases / Q000188:drug therapy / Q000628:therapy*; D002294:Carcinoma, Squamous Cell / Q000188:drug therapy / Q000628:therapy / Q000662:veterinary*; D002945:Cisplatin / Q000627:therapeutic use*; D003131:Combined Modality Therapy / Q000662:veterinary; D017679:Cryotherapy / Q000379:methods / Q000662:veterinary*; D005260:Female; D009303:Nasopharyngeal Neoplasms / Q000188:drug therapy / Q000628:therapy / Q000662:veterinary*; D009364:Neoplasm Recurrence, Local / Q000662:veterinary; D046429:Spheniscidae; D016896:Treatment Outcome
D000970:Antineoplastic Agents; D002945:Cisplatin