[Role of hair follicle stem cell in wound healing and correlative signals].
OBJECTIVE
To review the research progress of hair follicle stem cell (FSC) in wound healing and correlative signals.


METHODS
The advances in the FSC location, characters, relations with wound repair and correlative singals were introduced based on the recent related literature.


RESULTS
FSC played an important role in hair follicle cycle and wound healing. The correlative signals maybe Wnt, bone morphogenetic protein/transforming growth factor beta, Norch, Shh and fibroblast growth factor.


CONCLUSIONS
The multipotency and plasticity of FSC offer a new way in regeneration medicine and the signals in cell proliferation and differentiation will be the new focus in future research.
Wang
Hongtao
H
Department of Burn and Cutaneous Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an Shaanxi, 710032, P. R. China.
Chen
Bi
B
Hu
Dahai
D
D000818:Animals; D019485:Bone Morphogenetic Proteins / Q000502:physiology; D018859:Hair Follicle / Q000166:cytology*; D006801:Humans; D051379:Mice; D015398:Signal Transduction; D013234:Stem Cells / Q000166:cytology*; D016212:Transforming Growth Factor beta / Q000502:physiology; D051153:Wnt Proteins / Q000502:physiology; D014945:Wound Healing / Q000502:physiology*
D019485:Bone Morphogenetic Proteins; D016212:Transforming Growth Factor beta; D051153:Wnt Proteins