title: Acute upper airway obstruction from acquired angioedema.
abstract: C1 esterase inhibitor deficiency is an unusual cause of acute upper airway angioedema. This case of angioedema is secondary to acquired C1 esterase inhibitor deficiency associated with neoplastic disease and triggered by the use of angiotensin converting enzyme inhibitors. It was sufficiently severe to require emergency airway management. A guide to the evaluation and management of angioedema is presented.
authors.affiliation: Royal Adelaide Hospital and University of Adelaide, Adelaide, South Australia, Australia.
authors.forename: William Yc
authors.initials: WY
authors.lastname: Cheng
authors.forename: William B
authors.initials: WB
authors.lastname: Smith
authors.forename: W John
authors.initials: WJ
authors.lastname: Russell
mesh_terms: D000368:Aged; D000402:Airway Obstruction / Q000209:etiology* / Q000628:therapy; D000799:Angioedema / Q000139:chemically induced* / Q000150:complications*; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000009:adverse effects*; D050718:Complement C1 Inhibitor Protein / Q000378:metabolism*; D005260:Female; D006801:Humans; D007442:Intubation, Intratracheal; D017257:Ramipril / Q000009:adverse effects*; D014060:Tongue Diseases / Q000150:complications
chemical_list: D000806:Angiotensin-Converting Enzyme Inhibitors; D050718:Complement C1 Inhibitor Protein; D017257:Ramipril