title: Reactivity study of 1H-thieno[3,2-d][1,3]oxazine-2,4-dione toward the synthesis of bicyclic 3,4-dihydro-1H-thieno[3,2-e][1,4]diazepine-2,5-dione analogues.
abstract: A series of 10 optically pure 3,4-dihydro-1H-thieno[3,2-e][1,4]diazepine-2,5-dione derivatives has been synthesized in 41-75% yields on treatment of 1H-thieno[3,2-d][1,3]oxazine-2,4-dione with different natural alpha-amino acids.
authors.affiliation: Laboratoire des Aminoacides, Peptides et Protéines (LAPP), CNRS UMR 5810, UMI-UMII, UFR des Sciences Pharmaceutiques et Biologiques, 15 Avenue Charles Flahault, 34093 Montpellier Cedex 5, France.
authors.forename: Yann
authors.initials: Y
authors.lastname: Brouillette
authors.forename: Vincent
authors.initials: V
authors.lastname: Lisowski
authors.forename: Pierre
authors.initials: P
authors.lastname: Fulcrand
authors.forename: Jean
authors.initials: J
authors.lastname: Martinez
mesh_terms: D000577:Amides / Q000737:chemistry; D000812:Anhydrides / Q000737:chemistry; D001381:Azepines / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D010078:Oxazines / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: C519476:1H-thieno(3,2-d)(1,3)oxazine-2,4-dione; C519477:3,4-dihydro-1H-thieno(3,2-e)(1,4)diazepine-2,5-dione; D000577:Amides; D000812:Anhydrides; D001381:Azepines; D010078:Oxazines