title: Highly enantioselective water-compatible organocatalyst for Michael reaction of ketones to nitroolefins.
abstract: A chiral diamine was found to catalyze enantioselective addition of ketones to nitroolefins in aqueous/saline/organic media. The products were obtained with excellent diastereoselectivities (syn/anti = 99:1) and enantioselectivities up to 99%. The reaction could be facilitated using a mild acid. [reaction: see text]
authors.affiliation: Department of Chemistry, Indian Institute of Technology, Kanpur, India-208 016.
authors.lastname: Vishnumaya
authors.forename: Vinod K
authors.initials: VK
authors.lastname: Singh