title: Vascular risks and management of obesity in children and adolescents.
abstract: Childhood obesity has reached epidemic proportions in many countries. Pediatric obesity is associated with the development of cardiovascular (CV) risk factors including type 2 diabetes, hypertension, dyslipidemia, and the metabolic syndrome. It is also associated with an increased risk of CV disease (CVD) in adulthood. Moreover, obesity and CVD risk factors in obese youth tend to track into adulthood, further increasing the risk of adult CVD. Consequently, the treatment and prevention of childhood overweight and obesity has become a public health priority. Proper nutrition and increased physical activity are the main focus of these efforts; however, few studies have shown positive results. Treatment options for obesity in youth also include pharmacotherapy and surgery. While pharmacotherapy appears promising, additional evidence is needed, especially with respect to the long-term impact, before it becomes a widespread treatment option in the pediatric population.
authors.affiliation: School of Physical and Health Education, Queen's University, Kingston, Ontario, Canada.
authors.forename: Courtney J
authors.initials: CJ
authors.lastname: Jolliffe
authors.forename: Ian
authors.initials: I
authors.lastname: Janssen
mesh_terms: D050153:Abdominal Fat / Q000503:physiopathology; D000293:Adolescent; D017195:Adolescent Nutritional Physiological Phenomena; D000886:Anthropometry / Q000379:methods; D019440:Anti-Obesity Agents / Q000627:therapeutic use*; D050218:Body Fat Distribution; D015992:Body Mass Index; D002318:Cardiovascular Diseases / Q000209:etiology / Q000517:prevention & control*; D002648:Child; D002664:Child Nutritional Physiological Phenomena; D002675:Child, Preschool; D003924:Diabetes Mellitus, Type 2 / Q000209:etiology; D050171:Dyslipidemias / Q000209:etiology; D005081:Exercise Therapy; D005260:Female; D006801:Humans; D006973:Hypertension / Q000209:etiology; D008297:Male; D024821:Metabolic Syndrome; D009765:Obesity / Q000150:complications / Q000178:diet therapy / Q000188:drug therapy / Q000503:physiopathology / Q000601:surgery / Q000628:therapy*; D017410:Practice Guidelines as Topic; D015995:Prevalence; D012307:Risk Factors; D012720:Severity of Illness Index; D016896:Treatment Outcome
chemical_list: D019440:Anti-Obesity Agents