Heightened sense for sensing: recent advances in pathogen immunoassay sensing platforms.
Rapid and efficient sensors are essential for effective defense against the emerging threat of bioterrorism and biological warfare. This review article describes several recent immunosensing advances that are relevant to biothreat detection. These highly diverse examples are intended to demonstrate the breadth of these immunochemical sensing systems and platforms while highlighting those technologies that are suitable for pathogen detection.
Fischer
Nicholas O
NO
BioSecurity and NanoSciences Laboratory, Chemistry, Materials & Life Sciences Directorate, Lawrence Livermore National Laboratory, Livermore, CA 94551, USA.
Tarasow
Theodore M
TM
Tok
Jeffrey B-H
JB
D052157:Aptamers, Nucleotide; D001419:Bacteria / Q000302:isolation & purification; D001694:Biological Warfare; D015374:Biosensing Techniques / Q000379:methods*; D023482:Bioterrorism; D004867:Equipment Design; D005057:Eukaryotic Cells; D006801:Humans; D007118:Immunoassay / Q000379:methods*; D008863:Microspheres; D053770:Nanowires; D040081:Protein Array Analysis / Q000379:methods; D014771:Virion
D052157:Aptamers, Nucleotide