title: Laryngeal squamous cell carcinoma in a North American black bear (Ursus americanus).
abstract: A 10-yr-old female black bear (Ursus americanus) at the North Carolina Zoological Park presented with a 2-wk history of intermittent coughing and stertor. The animal was anesthetized for examination, and at intubation, a large mass associated with the tonsils and larynx was observed obstructing the airway. Cardiopulmonary collapse occurred during the procedure, and efforts at resuscitation were ineffective. At necropsy, an 8 cm times 6 cm times 5 cm mass was present in the larynx, infiltrating the epiglottis and obstructing the airway. Regional lymph nodes were mildly enlarged and contained tan inspissated substance. Histologically, the neoplasm was composed of nests of keratinizing squamous epithelial cells with evidence of lymphatic invasion and metastases to regional lymph nodes.
authors.affiliation: North Carolina State Zoological Park, 4401 Zoo Parkway, Asheboro, North Carolina 27203, USA.
authors.forename: David S
authors.initials: DS
authors.lastname: Rotstein
authors.forename: Pamela
authors.initials: P
authors.lastname: Govett
authors.forename: Barbara
authors.initials: B
authors.lastname: Wolfe
mesh_terms: D000402:Airway Obstruction / Q000209:etiology / Q000662:veterinary*; D000818:Animals; D000836:Animals, Zoo; D002294:Carcinoma, Squamous Cell / Q000150:complications / Q000175:diagnosis / Q000601:surgery / Q000662:veterinary*; D017809:Fatal Outcome; D005260:Female; D007822:Laryngeal Neoplasms / Q000150:complications / Q000175:diagnosis / Q000601:surgery / Q000662:veterinary*; D008207:Lymphatic Metastasis; D001503:Ursidae