Multicomponent reactions involving tricyclooxonium ylide intermediate: diastereoselective synthesis of mono- and bisalkoxyoctahydro-1,4-benzodioxocin-6(5H)-one frameworks.
A highly diastereoselective tandem ring-enlargement and aldol condensation process involving multicomponent reactions of ethereal tricyclooxonium ylide intermediate with alcohols, mono- or dialdehydes in the presence of titanium(iv) isopropoxide is described to furnish alkoxyoctahydro-1,4-benzodioxocin-6(5H)-one ring systems.
Muthusamy
Sengodagounder
S
School of Chemistry, Bharathidasan University, Tiruchirappalli, Tamilnadu, 620 024, India. muthu@bdu.ac.in
Krishnamurthi
Janagiraman
J
Suresh
Eringathodi
E