Central corneal thickness of Korean patients with glaucoma.
OBJECTIVE
To characterize the central corneal thickness (CCT) in Koreans and assess CCT variation in different types of glaucoma.


METHODS
Observational cross-sectional study.


METHODS
Patients previously diagnosed as primary open-angle glaucoma (POAG, n = 343), normal-tension glaucoma (NTG, n = 192), and ocular hypertension (OHT, n = 44), as well as nonglaucomatous patients (n = 224) examined in a glaucoma clinic in Korea.


METHODS
Participants' CCT was measured by ultrasound pachymetry.


METHODS
Mean CCT and its correlations with glaucoma diagnosis, age, spherical equivalent, gender, diabetes, and hypertension.


RESULTS
Mean CCT was highest in eyes with OHT (582.1 microm, P<0.0001), lowest in NTG (537.5 microm, P<0.0001), and intermediate and similar in eyes with POAG and healthy eyes (550.7 and 553.6 microm, respectively, P = 0.289). Central corneal thickness was inversely correlated with age (r = -0.12; P<0.0001). There was no statistically significant difference in mean CCT between eyes with different gender or presence of diabetes and hypertension. Mean CCT in normal and OHT eyes was weakly correlated with refractive error (P<0.05).


CONCLUSIONS
In Korean subjects, CCT is greatest in eyes with OHT and least in eyes with NTG.
Lee
Eun Suk
ES
Department of Ophthalmology, Inha University College of Medicine, Incheon, Korea.
Kim
Chan Yun
CY
Ha
Seung Joo
SJ
Seong
Gong Je
GJ
Hong
Young Jae
YJ
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003315:Cornea / Q000000981:diagnostic imaging / Q000473:pathology*; D003430:Cross-Sectional Studies; D003941:Diagnostic Techniques, Ophthalmological; D005260:Female; D005902:Glaucoma, Open-Angle / Q000000981:diagnostic imaging / Q000208:ethnology / Q000473:pathology*; D006801:Humans; D007429:Intraocular Pressure; D007723:Korea / Q000208:ethnology; D008297:Male; D008875:Middle Aged; D009798:Ocular Hypertension / Q000000981:diagnostic imaging / Q000208:ethnology / Q000473:pathology; D012189:Retrospective Studies; D014463:Ultrasonography