title: Clinical-epidemiological profile of children with schistosomal myeloradiculopathy attended at the Instituto Materno-Infantil de Pernambuco.
abstract: The most critical phase of exposure to schistosomal infection is the infancy, because of the more frequent contact with contaminated water and the immaturity of the immune system. One of the most severe presentations of this parasitosis is the involvement of the spinal cord, which prognosis is largely dependent on early diagnosis and treatment. Reports on this clinical form of schistosomiasis in children are rare in the literature. We present here the clinical-epidemiological profile of schistosomal myeloradiculopathy (SMR) from ten children who were admitted at the Instituto Materno-Infantil de Pernambuco over a five-year period. They were evaluated according to an investigation protocol. Most of these patients presented an acute neurological picture which included as the main clinical manifestations: sphincteral disorders, low back and lower limbs pain, paresthesia, lower limbs muscle weakness and absence of deep tendon reflex, and impairment of the gait. The diagnosis was presumptive in the majority of the cases. This study emphasizes the importance of considering the diagnosis of SMR in pediatric patients coming from endemic areas who present a low cord syndrome, in order to start the appropriate therapy and avoid future complications.
authors.affiliation: Laboratório de Esquistossomose, Centro de Pesquisas Aggeu Magalhães-Fiocruz, 50670-420 Recife, PE, Brazil. karina@cpqam.fiocruz.br
authors.forename: Karina Conceição G M
authors.initials: KC
authors.lastname: Araújo
authors.forename: Cristiana da
authors.initials: Cd
authors.lastname: Rosa e Silva
authors.forename: Constança Simões
authors.initials: CS
authors.lastname: Barbosa
authors.forename: Teresa C A
authors.initials: TC
authors.lastname: Ferrari
mesh_terms: D000293:Adolescent; D000871:Anthelmintics / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008297:Male; D020818:Neuroschistosomiasis / Q000175:diagnosis* / Q000188:drug therapy; D010073:Oxamniquine / Q000627:therapeutic use; D011241:Prednisone / Q000627:therapeutic use; D011843:Radiculopathy / Q000175:diagnosis* / Q000188:drug therapy / Q000469:parasitology; D012189:Retrospective Studies; D012555:Schistosomiasis mansoni / Q000175:diagnosis* / Q000188:drug therapy; D016896:Treatment Outcome
chemical_list: D000871:Anthelmintics; D010073:Oxamniquine; D011241:Prednisone