Sigma-chelation-directed C-H functionalizations using Pd(II) and Cu(II) catalysts: regioselectivity, stereoselectivity and catalytic turnover.
Recent progress in sigma-chelation directed C-H functionalization from the authors' group is described to illustrate the challenges and opportunities in the development of synthetically-useful catalytic reactions involving C-H activation as the key step. Emphasis is placed on strategies for developing catalysis under mild conditions and controlling regio- and stereoselectivity.
Yu
Jin-Quan
JQ
Department of Chemistry MS015, Brandeis University, Waltham, Massachusetts, 02454-9110, USA. yu200@brandeis.edu
Giri
Ramesh
R
Chen
Xiao
X
D002384:Catalysis; D002614:Chelating Agents / Q000138:chemical synthesis* / Q000737:chemistry; D003300:Copper / Q000737:chemistry*; D015394:Molecular Structure; D009930:Organic Chemicals / Q000138:chemical synthesis* / Q000737:chemistry; D010080:Oxazoles / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry*; D013237:Stereoisomerism
D002614:Chelating Agents; D009930:Organic Chemicals; D010080:Oxazoles; D010165:Palladium; D003300:Copper