[Effect of periodontitis on circulating C-reactive protein in type 2 diabetes patients].
OBJECTIVE
To investigate the effect of periodontal infection on circulating C-reactive protein (CRP) in type 2 diabetes patients.


METHODS
32 diabetes patients with advanced periodontitis participated in this study. They were compared to a group of 32 diabetes patients without periodontal disease, who were mathed with regard to age (+/- 3 years), gender and body mass index (+/- 1 kg/m2). The concentration of CRP on circulation was measured by ELISA.


RESULTS
Significant difference was found in the level of CRP and the percentage of subjects with elevated CRP levels > or = 3 mg/L on circulation between the two groups(P < 0.05).


CONCLUSIONS
Periodontal infection results in higher circulating CRP in type 2 diabetes patients. This elevated inflammatory factor may exacerbate insulin resistance and increase the risk for great vessels complications of diabetes mellitus.
Gu
Yu-Xin
YX
Dept. of Stomatology, The First Hospital of Hebei Medical University, Shijiazhuang 050031, China.
Li
Qing-Xing
QX
You
Yan-Ling
YL
Liu
Guang-Shun
GS
Han
Xu
X
D000328:Adult; D002097:C-Reactive Protein; D003924:Diabetes Mellitus, Type 2; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D017622:Periodontal Attachment Loss; D010514:Periodontal Pocket; D010518:Periodontitis
D002097:C-Reactive Protein