Physiological macrocytosis of pregnancy.
In a prospective study of 40 women, mean corpuscular volume (MCV) values in second and third trimesters were compared between women who were iron deficient and those who were iron replete. There was no difference in the two groups. Hence reduced MCV seen in iron deficiency anaemia cannot be relied upon as an effective marker in pregnancy due to physiological macrocytosis.
Mukhopadhyay
Asima
A
Department of Obstetrics & Gynaecology, All India Institute of Medical Sciences, New Delhi-110029, India.
Bhatla
Neerja
N
Kriplani
Alka
A
Saxena
Renu
R
D018798:Anemia, Iron-Deficiency / Q000097:blood / Q000175:diagnosis*; D004909:Erythrocyte Indices; D005260:Female; D005293:Ferritins / Q000097:blood; D006400:Hematocrit; D006801:Humans; D011237:Predictive Value of Tests; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000097:blood / Q000175:diagnosis*; D011262:Pregnancy Trimester, Second; D011263:Pregnancy Trimester, Third; D011296:Prenatal Diagnosis; D011446:Prospective Studies; D012680:Sensitivity and Specificity
D005293:Ferritins