[Enzyme DNA-ase use in patients with maxillofacial abscesses and phlegmons].
The results of the clinical studies indicate that DNAase treatment of the patients with maxillofacial abscesses and phlegmons increases the effect of antibacterial therapy. During microbiologic testing in the patients treated with DNAase together with antibacterial therapy it was recorded a marked decrease in the plating of bacteria. This effect is supposed to be connected with enzyme ability to penetrate into microbial biofilms and disturb microbial interactions.
Solov'ev
M M
MM
Tets
V V
VV
Bobrov
A P
AP
Artemenko
K L
KL
Moshkevich
I R
IR
Tets
G V
GV
D000038:Abscess / Q000188:drug therapy*; D000293:Adolescent; D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002481:Cellulitis / Q000188:drug therapy*; D003851:Deoxyribonucleases / Q000627:therapeutic use*; D004357:Drug Synergism; D004359:Drug Therapy, Combination; D005500:Follow-Up Studies; D006801:Humans; D008439:Maxillary Diseases / Q000188:drug therapy*; D008875:Middle Aged; D012189:Retrospective Studies; D016896:Treatment Outcome
D000900:Anti-Bacterial Agents; D003851:Deoxyribonucleases