title: Mycobacterium tuberculosis sternal wound infection after open heart surgery: a case report and review of the literature.
abstract: Tuberculous osteomyelitis of sternum after open heart surgery is a rare disease entity. We report a case of wound infection with osteomyelitis caused by Mycobacterium tuberculosis in a patient with diabetic nephropathy, requiring peritoneal dialysis after coronary artery bypass grafting, who was successfully treated with antituberculous agents and surgical debridement. In addition, we provide a literature review on reported cases of tuberculous sternal osteomyelitis and mediastinitis after open heart surgery, and discuss about the risk factors, clinical features, and treatment of this infection.
authors.affiliation: Department of Microbiology, Research Centre of Infection and Immunology, The University of Hong Kong, Queen Mary Hospital, Pokfulam, Hong Kong.
authors.forename: Teresa K
authors.initials: TK
authors.lastname: Wang
authors.forename: Chi-Fong
authors.initials: CF
authors.lastname: Wong
authors.forename: Wing-Kuk
authors.initials: WK
authors.lastname: Au
authors.forename: Vincent C
authors.initials: VC
authors.lastname: Cheng
authors.forename: Samson S
authors.initials: SS
authors.lastname: Wong
mesh_terms: D000904:Antibiotics, Antitubercular / Q000627:therapeutic use; D001026:Coronary Artery Bypass / Q000009:adverse effects*; D003646:Debridement; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009169:Mycobacterium tuberculosis / Q000472:pathogenicity*; D010019:Osteomyelitis / Q000188:drug therapy / Q000382:microbiology* / Q000601:surgery; D013249:Sternum / Q000382:microbiology*; D013530:Surgical Wound Infection / Q000188:drug therapy / Q000382:microbiology*
chemical_list: D000904:Antibiotics, Antitubercular