title: The synchronization properties of a network of inhibitory interneurons depend on the biophysical model.
abstract: The synchronization properties of a pair of coupled fast spiking interneurons are studied by using the theory of weakly coupled oscillators. Four different biophysical models of the single fast spiking interneuron are used and the corresponding results are compared. It is shown that for a pair of identical coupled cells, the synchronization properties are model-dependent. In particular, the firing coherence of the network is strongly affected by the reversal potential, the kinetics of the inhibitory postsynaptic current and the electrical coupling; the activation properties of the sodium and potassium currents play a significant role too.
authors.affiliation: Istituto di Biofisica CNR, Sezione di Pisa, Via G. Moruzzi 1, 56124 Pisa, Italy. digarbo@ib.cnr.it
authors.forename: Angelo
authors.initials: A
authors.lastname: Di Garbo
authors.forename: Michele
authors.initials: M
authors.lastname: Barbi
authors.forename: Santi
authors.initials: S
authors.lastname: Chillemi
mesh_terms: D000200:Action Potentials; D000818:Animals; D055592:Biophysical Phenomena; D001703:Biophysics; D007395:Interneurons / Q000502:physiology*; D007700:Kinetics; D008433:Mathematics; D008959:Models, Neurological; D009415:Nerve Net / Q000502:physiology*; D013569:Synapses / Q000502:physiology; D049490:Systems Biology