title: The assessment of oral health-related quality of life by factor analysis in patients with Behcet's disease and recurrent aphthous stomatitis.
abstract: BACKGROUND
  The aim of the study was to test multidimensional properties of oral health impact profile-14 (OHIP-14) in Behcet's disease (BD) and recurrent aphthous stomatitis (RAS) patients with active oral ulcers.
  
  
  METHODS
  Ninety-six BD patients, 28 patients with RAS and 117 healthy controls (HC) were included in this study. In patients with active oral ulcers, the frequency and healing time of ulcers were recorded. Multidimensional properties of OHIP-14 were examined by factor analysis.
  
  
  RESULTS
  Factor analysis revealed three subscales and explained 66.49% of overall variance in these patients with active oral ulcers. The score of Subscale 1 was positively correlated with the recurrence of oral ulcers per month (P = 0.037). Subscale 3 scores of the patients treated with colchicine were worse than those treated with immunosuppressives (P = 0.035).
  
  
  CONCLUSIONS
  The factor structure of OHIP-14 was found to be reliable and sensitive to clinical parameters and treatment modalities in active patients.
authors.affiliation: Department of Basic Health Science, Faculty of Health Education, Marmara University, Istanbul, Turkey. goncamumcu@marmara.edu.tr
authors.forename: G
authors.initials: G
authors.lastname: Mumcu
authors.forename: O
authors.initials: O
authors.lastname: Hayran
authors.forename: D O
authors.initials: DO
authors.lastname: Ozalp
authors.forename: N
authors.initials: N
authors.lastname: Inanc
authors.forename: S
authors.initials: S
authors.lastname: Yavuz
authors.forename: T
authors.initials: T
authors.lastname: Ergun
authors.forename: H
authors.initials: H
authors.lastname: Direskeneli
mesh_terms: D000328:Adult; D000704:Analysis of Variance; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D001528:Behcet Syndrome / Q000188:drug therapy / Q000523:psychology*; D016022:Case-Control Studies; D003078:Colchicine / Q000627:therapeutic use; D005163:Factor Analysis, Statistical; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008297:Male; D025341:Principal Component Analysis; D011788:Quality of Life; D018434:Sickness Impact Profile; D013281:Stomatitis, Aphthous / Q000188:drug therapy / Q000523:psychology*; D050257:Tubulin Modulators / Q000627:therapeutic use
chemical_list: D000900:Anti-Bacterial Agents; D000893:Anti-Inflammatory Agents; D007166:Immunosuppressive Agents; D050257:Tubulin Modulators; D003078:Colchicine