Mini outbreak of Kaposi's varicelliform eruption in skin ward: a study of five cases.
BACKGROUND
Kaposis varicelliform eruption (KVE) represents widespread cutaneous herpes simplex virus (HSV) infection in patients with preexisting dermatoses. Occasionally, this infection can present as a nosocomial infection in skin wards, if adequate bed-spacing and barrier nursing methods are not followed. We are reporting five cases of KVE; four cases acquired the infection in a makeshift ward after admission of the first case in May 2005, due to the renovation work of the regular skin ward.


OBJECTIVE
The purpose of this study is to create clinical awareness about this uncommon dermatologic entity and to stress upon the importance of bed-spacing and barrier nursing in skin wards.


METHODS
Five cases of KVE, three females and two males with different primary dermatoses (pemphigus foliaceus--one, pemphigus vulgaris--two, paraneoplastic pemphigus--one and toxic epidemal necrolysis--one) were included in this study. Diagnosis was made clinically and supported with Tzanck smear and HSV serology. All the cases were treated with oral acyclovir.


RESULTS
Four out of five cases of KVE recovered with treatment, one case of extensive pemphigus vulgaris with KVE succumbed to death.


CONCLUSIONS
Mini outbreaks of KVE can occur in skin wards with inadequate bed-spacing and overcrowding of patients. Therefore adequate bed-spacing, barrier nursing and isolation of suspected cases are mandatory to prevent such life-threatening infections.
Rao
Grr
G
Department of Dermatology, Andhra Medical College, Visakhapatnam, Andhra Pradesh, India. graghurmamrao@hotmail.com
Chalam
K V
KV
Prasad
G P
GP
Sarnathan
M
M
Kumar
Hky
H
D000212:Acyclovir / Q000008:administration & dosage / Q000627:therapeutic use; D000284:Administration, Oral; D000328:Adult; D000998:Antiviral Agents / Q000008:administration & dosage / Q000627:therapeutic use; D002648:Child; D003428:Cross Infection / Q000453:epidemiology*; D003441:Crowding; D003880:Dermatology; D004196:Disease Outbreaks; D017809:Fatal Outcome; D005260:Female; D006742:Hospital Bed Capacity; D006748:Hospital Departments; D006801:Humans; D007194:India / Q000453:epidemiology; D007617:Kaposi Varicelliform Eruption / Q000150:complications / Q000188:drug therapy / Q000453:epidemiology* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D010362:Patients' Rooms; D012871:Skin Diseases / Q000150:complications; D016896:Treatment Outcome
D000998:Antiviral Agents; D000212:Acyclovir