title: Promoting helicity in carbohydrate-containing foldamers through long-range hydrogen bonds.
abstract: A sensor system to probe the propensity of carbohydrates to induce helical structures through long-range hydrogen bonds, based on a C(2)-symmetric xylylene bis(thiourea) arrangement, is reported; the formation of intermolecular complexes with benzoate anion promotes helix uncoiling, the free energy of the process being related to helix stability.
authors.affiliation: Departamento de Química Orgánica, Facultad de Química, Universidad de Sevilla, Apartado 553, E-41071 Sevilla, Spain.
authors.forename: David
authors.initials: D
authors.lastname: Rodríguez-Lucena
authors.forename: Juan M
authors.initials: JM
authors.lastname: Benito
authors.forename: Carmen Ortiz
authors.initials: CO
authors.lastname: Mellet
authors.forename: José M
authors.initials: JM
authors.lastname: García Fernández
mesh_terms: D001565:Benzoates / Q000737:chemistry; D002236:Carbohydrate Conformation; D002241:Carbohydrates / Q000737:chemistry*; D006860:Hydrogen Bonding; D007202:Indicators and Reagents; D009682:Magnetic Resonance Spectroscopy; D008958:Models, Molecular
chemical_list: D001565:Benzoates; D002241:Carbohydrates; D007202:Indicators and Reagents