Immune reconstitution sarcoidosis presenting with hypercalcaemia and renal failure in HIV infection.
An HIV-positive white man developed hypercalcaemia and renal failure 15 months after starting highly active antiretroviral therapy. Investigations showed systemic sarcoidosis affecting parotids, skin and kidneys. This presentation was thought to be a manifestation of immune reconstitution inflammatory syndrome, and the patient was successfully treated with corticosteroid therapy.
Ferrand
R A
RA
University College London Hospitals, London NW1 2BU, UK; Camden Primary Care Trust, Mortimer Market Centre, London WC1E 6AU, UK.
Cartledge
J D
JD
Connolly
J
J
Standish
R A
RA
Miller
R F
RF
D017088:AIDS-Related Opportunistic Infections / Q000150:complications* / Q000188:drug therapy / Q000276:immunology; D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D023241:Antiretroviral Therapy, Highly Active; D015658:HIV Infections / Q000150:complications / Q000188:drug therapy / Q000276:immunology*; D006801:Humans; D006934:Hypercalcemia / Q000188:drug therapy / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D051437:Renal Insufficiency / Q000188:drug therapy / Q000209:etiology*; D012507:Sarcoidosis / Q000150:complications* / Q000188:drug therapy
D000305:Adrenal Cortex Hormones