Assessment and reproducibility of anterior chamber depth measurement with anterior segment optical coherence tomography compared with immersion ultrasonography.
OBJECTIVE
To measure anterior chamber depth (ACD) with an anterior segment optical coherence tomography (AS-OCT) and a standard ultrasonic (US) axial scan (A-scan) device using an immersion technique and to assess repeatability, reproducibility, and correlations of the measurements.


METHODS
Department of Ophthalmology, Medical Health and Science Center, University of Debrecen, Debrecen, Hungary.


METHODS
Sixty healthy eyes of 41 patients were enrolled in a study. The central ACD was measured 5 times with AS-OCT (Visante, Carl Zeiss Meditec) using its chamber tool and 5 times with a US A-scan device (UltraScan Imaging System, Alcon Laboratories) using an immersion method. The measurements were performed consecutively by 2 independent observers.


RESULTS
The mean ACD measured with AS-OCT was 3.12 mm +/- 0.33 (SD) by observer 1 and 3.11 +/- 0.33 mm by observer 2 (P = .78). The repeatability was 0.8% +/- 0.4% and 1.9% +/- 1.4%, respectively. The reproducibility was 0.23%. The reliability coefficient with AS-OCT was 99.6%. The mean ACD measured with immersion US A-scan was 2.98 +/- 0.33 mm by observer 1 and 2.95 +/- 0.34 mm by observer 2 (P = .68) . The repeatability was 6.4% +/- 3.8% by observer 1 and 8.5% +/- 4.9% by observer 2. The reproducibility was 0.88%. The reliability coefficient was 87.1% for US A-scan measurements. The difference between ACD values with AS-OCT and values with US A-scan was statistically significant (P = .02). The correlation (r) between AS-OCT and US A-scan was 0.732 (P<.0001) by observer 1 and 0.802 (P<.0001) by observer 2.


CONCLUSIONS
Anterior chamber measurements were significantly deeper with AS-OCT than with US immersion A-scan. Repeatability of ACD measurements was better with AS-OCT than with immersion US, and reproducibility was equal with the 2 methods.
Nemeth
Gabor
G
Department of Ophthalmology, Medical Health and Science Center, University of Debrecen, Debrecen, Hungary. nemeth222@yahoo.com
Vajas
Attila
A
Tsorbatzoglou
Alexis
A
Kolozsvari
Bence
B
Modis
Laszlo
L
Berta
Andras
A
D000867:Anterior Chamber / Q000000981:diagnostic imaging*; D000886:Anthropometry / Q000379:methods; D001699:Biometry; D003941:Diagnostic Techniques, Ophthalmological; D006801:Humans; D008875:Middle Aged; D015203:Reproducibility of Results; D041623:Tomography, Optical Coherence / Q000379:methods*; D014463:Ultrasonography / Q000379:methods