Thiazolium-derived N-heterocyclic carbene-catalyzed cross-coupling of aldehydes with unactivated imines.
Cross-coupling of aromatic aldehydes or benzoins with unactivated imines catalyzed by an N-heterocyclic carbene (NHC) affords alpha-amino ketones smoothly.
Li
Gong-Qiang
GQ
State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 354 Fenglin Lu, Shanghai 200032, P. R. China.
Dai
Li-Xin
LX
You
Shu-Li
SL
D000447:Aldehydes / Q000138:chemical synthesis* / Q000737:chemistry*; D001573:Benzoin / Q000737:chemistry; D002384:Catalysis; D006571:Heterocyclic Compounds / Q000737:chemistry*; D007097:Imines / Q000138:chemical synthesis* / Q000737:chemistry*; D007202:Indicators and Reagents; D007659:Ketones / Q000138:chemical synthesis* / Q000737:chemistry*; D013844:Thiazoles / Q000138:chemical synthesis*
D000447:Aldehydes; D006571:Heterocyclic Compounds; D007097:Imines; D007202:Indicators and Reagents; D007659:Ketones; D013844:Thiazoles; D001573:Benzoin