[A clinical study on the diagnostic value of capsule endoscopy and multiple-detector computer tomography in obscure gastrointestinal bleeding].
OBJECTIVE
To evaluate the diagnostic value of capsule endoscopy (CE) and multiple-detector computer tomography (MDCT) in obscure gastrointestinal bleeding.


METHODS
The diagnostic value of CE was compared with that of MDCT in patients with obscure gastrointestinal bleeding. 60 patients (35 men, 25 women; mean age 53.8 years, range 17 - 84 years) with obscure gastrointestinal bleeding were enrolled in the study. All underwent gastroscopy and colonoscopy, but definite diagnosis was not made, then all of them underwent MDCT followed by CE.


RESULTS
Natural excretion of the capsule occurred in 58 (96.7%) patients. CE identified positive findings in 36 (60.0%) patients and MDCT identified positive findings in 23 (38.3%) patients, P < 0.01. One patient was found to have 2 lesions simultaneously with CE. CE combined with MDCT identified positive findings in 40 (66.7%) patients. When this result was compared with that of CE, P > 0.05; whereas, compared with MDCT, P < 0.01. 28 patients underwent operations at last; the lesions accounting for bleeding all located in small intestine (16 in jejunum, 12 in ileum).


CONCLUSIONS
Diagnostic yield of CE was higher than that of MDCT in patients of obscure gastrointestinal bleeding. Combining CE with MDCT did not increase the diagnostic yield in obscure gastrointestinal bleeding. However, MDCT showed more extraintestinal lesions, it is suggested that patients with obscure gastrointestinal bleeding be examined not only with CE but also MDCT.
Zhang
Bing-ling
BL
Department of Gastroenterology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310003, China.
Zhong
Bai-shu
BS
Li
You-ming
YM
Chen
Chun-xiao
CX
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D053704:Capsule Endoscopy; D005260:Female; D006471:Gastrointestinal Hemorrhage / Q000000981:diagnostic imaging* / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008297:Male; D008875:Middle Aged; D036542:Tomography, Spiral Computed