title: Antioxidant flavonoids and isoflavonoids from rhizomes of Iris pseudopumila.
abstract: Chromatographic separation of a methanolic extract from Iris pseudopumila rhizomes led to the isolation of two new natural compounds, irilone 4'-O-[beta-D-glucopyranosyl-(1-->6)-beta-D-glucopyranoside] and isoscutellarein 6-C-beta-D-glucopyranoside, along with 9 isoflavonoids and 4 flavonoids. Their structures were determined on the basis of spectroscopic evidence. Isolated compounds were evaluated for their antioxidant activity using the luminol-dependent chemiluminescence assay, with quercetin as a positive control. Irilone 4'-O-beta-D-glucopyranoside and kaempferol 3-O-[alpha-L-rhamnopyranosyl-(1-->6)-beta-D-glucopyranoside] showed significant antioxidant activity.
authors.affiliation: Department of Chemistry of Natural Products, University of Naples Federico II, Italy. drigano@unina.it
authors.forename: Daniela
authors.initials: D
authors.lastname: Rigano
authors.forename: Carmen
authors.initials: C
authors.lastname: Formisano
authors.forename: Armando
authors.initials: A
authors.lastname: Grassia
authors.forename: Gianluca
authors.initials: G
authors.lastname: Grassia
authors.forename: Angela
authors.initials: A
authors.lastname: Perrone
authors.forename: Sonia
authors.initials: S
authors.lastname: Piacente
authors.forename: Maria Luisa
authors.initials: ML
authors.lastname: Vuotto
authors.forename: Felice
authors.initials: F
authors.lastname: Senatore
mesh_terms: D000975:Antioxidants / Q000008:administration & dosage / Q000737:chemistry / Q000494:pharmacology* / Q000627:therapeutic use; D004305:Dose-Response Relationship, Drug; D005419:Flavonoids / Q000008:administration & dosage / Q000737:chemistry / Q000494:pharmacology / Q000627:therapeutic use; D006801:Humans; D007498:Iris; D007529:Isoflavones / Q000008:administration & dosage / Q000737:chemistry / Q000494:pharmacology / Q000627:therapeutic use; D049449:Luminescence; D008517:Phytotherapy; D010936:Plant Extracts / Q000008:administration & dosage / Q000737:chemistry / Q000494:pharmacology* / Q000627:therapeutic use; D027343:Rhizome
chemical_list: D000975:Antioxidants; D005419:Flavonoids; D007529:Isoflavones; D010936:Plant Extracts