Moderate exercise-induced energy expenditure does not alter leptin levels in sedentary obese men.
OBJECTIVE
The purpose of the study was to determine whether exercise-induced increases in energy expenditure (EE) alter circulating leptin levels in obese individuals.


METHODS
Participants were randomized to an exercise intervention group (n = 8) or nonexercising control (n = 7).


METHODS
All data were collected on an outpatient basis at the exercise physiology laboratory at the University of Central Florida.


METHODS
Fifteen healthy obese males (24.9 +/- 1.4 years old, body mass index 33.4 +/- 0.7 kg . m).


METHODS
Members of the intervention group underwent a single exercise session of moderate intensity (58.4 +/- 1.3% of VO2max) for 60 minutes.


METHODS
Postexercise, 24 hour postexercise, and 48 hour postexercise levels of leptin, insulin, and ghrelin.


RESULTS
The exercise session elicited an EE of 567 +/- 25 Kcal. No significant main effect or time-by-group interactions for leptin or ghrelin were observed immediately after the exercise bout or in the days following the intervention.


CONCLUSIONS
These preliminary data suggest that a bout of acute exercise of moderate intensity and duration does not affect leptin concentration. It is possible that a higher level of EE is required to elicit substantial changes.
Kyriazis
George A
GA
Center for Lifestyle Medicine and Department of Health Professions, University of Central Florida, 12201 Research Parkway, Orlando, FL 32826, USA.
Caplan
Jonathan D
JD
Lowndes
Joshua
J
Carpenter
Richard L
RL
Dennis
Karen E
KE
Sivo
Stephen A
SA
Angelopoulos
Theodore J
TJ
D000328:Adult; D004734:Energy Metabolism; D015444:Exercise / Q000502:physiology*; D054439:Ghrelin; D006801:Humans; D020738:Leptin / Q000097:blood / Q000502:physiology*; D008297:Male; D009043:Motor Activity / Q000502:physiology*; D009765:Obesity / Q000503:physiopathology*; D036361:Peptide Hormones / Q000097:blood; D011446:Prospective Studies; D012737:Sex Factors; D011795:Surveys and Questionnaires; D013997:Time Factors
D054439:Ghrelin; D020738:Leptin; D036361:Peptide Hormones