title: Case report: cefazolin-induced hemolytic anemia.
abstract: Antibiotic-induced hemolytic anemia is a rare complication. Prophylactic cephalosporins are widely used in patients having orthopaedic procedures. When there is a precipitous drop in hemoglobin levels, it is important for the clinician to consider the possibility of drug-induced anemia when other causes of blood loss have been excluded. We present a patient with no prior drug allergies who had antibiotic-induced hemolytic anemia develop after total knee arthroplasty.
authors.affiliation: Department of Orthopaedic Surgery, Hahnemann University Hospital, Philadelphia, PA 19102, USA.
authors.forename: Douglas L
authors.initials: DL
authors.lastname: Cerynik
authors.forename: Gwo-Chin
authors.initials: GC
authors.lastname: Lee
authors.forename: Reginald
authors.initials: R
authors.lastname: Fayssoux
authors.forename: Nirav H
authors.initials: NH
authors.lastname: Amin
mesh_terms: D000743:Anemia, Hemolytic / Q000139:chemically induced*; D000900:Anti-Bacterial Agents / Q000009:adverse effects*; D019072:Antibiotic Prophylaxis; D019645:Arthroplasty, Replacement, Knee; D002437:Cefazolin / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008875:Middle Aged
chemical_list: D000900:Anti-Bacterial Agents; D002437:Cefazolin