title: Multicomponent synthesis of dihydrobenzoxazepinones by coupling Ugi and Mitsunobu reactions.
abstract: Various dihydrobenzo[f][1,4]oxazepin-5-ones have been convergently prepared in 2-3 steps by coupling Ugi and Mitsunobu reactions. Two alternative methodologies were used: in the first one the Ugi condensation was followed by a Mitsunobu cyclization (2 steps); in the second one an intermolecular Mitsunobu reaction was followed by a deprotection step and then by an intramolecular Ugi reaction. Also a "convertible" isocyanide was used.
authors.affiliation: Department of Chemistry and Industrial Chemistry, via Dode- caneso 31, 16146, Genova, Italy. banfi@chimica.unige.it
authors.forename: Luca
authors.initials: L
authors.lastname: Banfi
authors.forename: Andrea Basso Giuseppe
authors.initials: AB
authors.lastname: Guanti
authors.forename: Paulina
authors.initials: P
authors.lastname: Lecinska
authors.forename: Renata
authors.initials: R
authors.lastname: Riva
mesh_terms: D003500:Cyclization; D015394:Molecular Structure; D010077:Oxazepines / Q000138:chemical synthesis* / Q000737:chemistry; D010078:Oxazines / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D010077:Oxazepines; D010078:Oxazines