title: [Itraconazole for treatment of fungal infections in patients undergoing allogeneic hematopoietic stem cell transplantation].
abstract: OBJECTIVE
  To investigate the effect of intravenous itraconazole on fungal infections in patients undergoing allogeneic hematopoietic stem cell transplantation.
  
  
  METHODS
  Seventy-five such patients treated with itraconazole from October, 2002 to October, 2005 were studied. The diagnosis of fungal infection was made according to the criteria recommended by Chinese workshop on invasive fungal infection (IFI). Four patients were definitely diagnosed as IFI, twenty-two patients probably and 49 patients possibly.
  
  
  RESULTS
  Fifty-seven of the 75 patients showed response to itraconazole therapy including 3 definite, 18 probable and 36 possible cases.
  
  
  CONCLUSIONS
  Fungal infections in patients undergoing allogeneic stem cell transplantation diagnosed according to the criteria recommended by Chinese workshop on IFI can be successfully treated with itraconazole.
authors.affiliation: Institute of Hematology, Peking University People's Hospital, Beijing 100044, China.
authors.forename: Jing-zhi
authors.initials: JZ
authors.lastname: Wang
authors.forename: Dai-hong
authors.initials: DH
authors.lastname: Liu
authors.forename: Lan-ping
authors.initials: LP
authors.lastname: Xu
authors.forename: Huan
authors.initials: H
authors.lastname: Chen
authors.forename: Kai-yan
authors.initials: KY
authors.lastname: Liu
authors.forename: Xiao-jun
authors.initials: XJ
authors.lastname: Huang
mesh_terms: D000293:Adolescent; D000328:Adult; D000935:Antifungal Agents / Q000627:therapeutic use*; D002648:Child; D005260:Female; D018380:Hematopoietic Stem Cell Transplantation; D006801:Humans; D017964:Itraconazole / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D009181:Mycoses / Q000188:drug therapy*; D014184:Transplantation, Homologous
chemical_list: D000935:Antifungal Agents; D017964:Itraconazole