Preliminary tests of a new reversible male contraceptive in bush dog, Speothos venaticus: open-ended vasectomy and microscopic reversal.
Open-ended vasectomies were performed on four male bush dogs (Speothos venaticus), with three having microscopic reversal surgery (vasovasostomy) between 10 and 20 mo post-vasectomy. The key to ease of reversal is leaving the distal (testicular) end open to allow leakage, resulting in a pressure-relieving granuloma. The proximal (abdominal) end is cauterized, providing an effective seal. This technique prevents the buildup of pressure in the epididymis, therefore limiting damage to the male's reproductive capacity. Described here are detailed procedures for both surgeries. One of the three males that underwent vasovasostomy has successfully impregnated his female partner. This study demonstrates that these techniques can be successfully applied to animals. With the two remaining pairs, none of the four individuals were proven breeders prior to the study, so it is not possible to eliminate the possibility of previously existing infertility. This technique may have limited application for carnivores, because vasectomy does not prevent potential adverse effects to females from prolonged, cyclic exposure to endogenous progesterone. In other taxonomic groups (e.g., primates, ungulates, marsupials, and rodents) in which multimale groupings are common, this reversible male sterilization technique could provide managers with the ability to control which males reproduce without eliminating their future reproductive capacity or social interaction.
DeMatteo
Karen
K
Saint Louis Zoo, St. Louis, Missouri 63110, USA.
Silber
Sherman
S
Porton
Ingrid
I
Lenahan
Kathy
K
Junge
Randall
R
Asa
Cheryl
C
D000818:Animals; D002335:Carnivora / Q000502:physiology / Q000601:surgery*; D008297:Male; D008866:Microsurgery / Q000379:methods / Q000662:veterinary; D011312:Pressure / Q000009:adverse effects; D013243:Sterilization Reversal / Q000379:methods / Q000662:veterinary*; D014649:Vas Deferens / Q000601:surgery; D014659:Vasectomy / Q000379:methods / Q000662:veterinary*