title: [Acute renal failure in critically ill patients].
abstract: Acute renal failure (ARF) is characterized by a sudden increase in plasma creatinine and a decrease in urine flow. ARF is caused by multiple factors of which the most important are hypovolemia, hypotension, septic mediators and nephrotoxic agents. ARF is observed in 10-23% of critically ill patients. The mortality of critically ill patients in whom ARF has developed is 50-70%. If the patient survives, the recovery of renal function is 90-95%. Non-dialytic therapy is early volume resuscitation whereas furosemid may worsen ARF. At the present time the dialytic therapy of choice in ICU patients with ARF is continuous renal replacement therapy (CRRT).
authors.affiliation: Odense Universitetshospital, Anaestesiologisk-intensiv Afdeling V, Odense C. palle.toft@ouh.fyns-amt.dk
authors.forename: Palle
authors.initials: P
authors.lastname: Toft
authors.forename: Torben
authors.initials: T
authors.lastname: Gilsaa
mesh_terms: D058186:Acute Kidney Injury / Q000209:etiology / Q000401:mortality / Q000628:therapy; D003422:Critical Care / Q000379:methods*; D016638:Critical Illness / Q000401:mortality / Q000628:therapy; D006440:Hemofiltration / Q000379:methods; D006801:Humans; D011379:Prognosis; D006435:Renal Dialysis / Q000379:methods; D017582:Renal Replacement Therapy / Q000379:methods*; D015996:Survival Rate