Supracervical hysterectomy in patients with advanced epithelial ovarian cancer.
OBJECTIVE
To assess whether supracervical hysterectomy (SCH) is a reasonable alternative to total abdominal hysterectomy in patients with advanced ovarian cancer.


METHODS
We reviewed the records of patients with advanced ovarian cancer who underwent a SCH at one institution between 1993 and 2004 and a similar cohort who underwent total abdominal hysterectomy (TAH) at the same institution during the same period. Patients without complete surgical staging done at the institution were excluded. Independent-sample t tests, Fisher exact test, and log rank tests were used for statistical analysis.


RESULTS
The study included 47 patients who underwent SCH (mean age, 59.6 years) and 190 who underwent TAH. There were no significant differences between the two groups in age (P=.51), preoperative CA 125 level (P=.55), or receipt of taxane-based and platinum-based chemotherapy (P=.84). Although limited by sample size, there were no significant differences between the two groups in rates of intraoperative complications (4 of 47 in the SCH group, or 8.5%, compared with 7 of 190 in the TAH group, or 3.7%; P=.24), vaginal or cervical recurrence (5 of 47 in the SCH group, or 10.6%, compared with 22 of 190 in the TAH group, or 11.6%; P=1.00), or in progression-free survival (SCH of 1.01 years compared with TAH of 1.19 years; P=.64) or overall survival (SCH of 3.28 years compared with TAH of 3.36 years; P=.12).


CONCLUSIONS
Supracervical hysterectomy may be a reasonable alternative to TAH in patients with advanced ovarian cancer.


METHODS
II.
Milam
Michael R
MR
Department of Gynecologic Oncology, the University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, USA.
Sood
Anil K
AK
King
Sara
S
Bassett
Roland L
RL
Lu
Karen H
KH
Slomovitz
Brian M
BM
Coleman
Robert L
RL
Ramirez
Pedro T
PT
D005260:Female; D006801:Humans; D007044:Hysterectomy / Q000379:methods* / Q000401:mortality; D007431:Intraoperative Complications / Q000453:epidemiology; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000188:drug therapy / Q000401:mortality / Q000601:surgery*; D012189:Retrospective Studies; D016019:Survival Analysis; D016896:Treatment Outcome