title: [Oral-maxillofacial malignant tumors: an initial study with in vivo single-voxel 1H MR spectroscopy].
abstract: OBJECTIVE
  To investigate the possibility of using single-voxel (1)H MR spectroscopy to evaluate malignant soft tissue tumors of oral-maxillofacial region.
  
  
  METHODS
  Forty-two patients with oral-maxillofacial malignant tumors, examined by single-voxel (1)H MR spectroscopy at a 1.5 T MR unit before treatment and confirmed by histo-pathological examination, were retrospectively studied. The localization for (1)H MR spectroscopy was used with a point-resolved spectroscopy (PRESS) at echo time of 144 ms. Choline (Cho), one of tumor's metabolites, was considered as a criterion to assess the malignant tumors.
  
  
  RESULTS
  Of 42 oral-maxillofacial malignant tumors, the Cho peak was identified in 37 lesions, including 15 of 17 squamous cell carcinomas, 9 of 12 salivary carcinomas, and 13 of 13 sarcomas and non-Hodgkin lymphomas.
  
  
  CONCLUSIONS
  Single-voxel (1)H MR spectroscopy might provide useful information for the assessment of malignant soft tissue tumors in the oral-maxillofacial region. Most malignant tumors in this study were characteristic of containing Cho metabolites. The Cho peak was more frequently recognized in the sarcomas and non-Hodgkin lymphomas than in the carcinomas.
authors.affiliation: Department of Radiology, School of Stomatology, Ninth People's Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200011, China. yuqiang6155@163.com
authors.forename: Qiang
authors.initials: Q
authors.lastname: Yu
authors.forename: Ping-zhong
authors.initials: PZ
authors.lastname: Wang
authors.forename: Hui-min
authors.initials: HM
authors.lastname: Shi
authors.forename: Ji-cheng
authors.initials: JC
authors.lastname: Luo
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002794:Choline / Q000032:analysis*; D005153:Facial Neoplasms / Q000737:chemistry / Q000175:diagnosis*; D005260:Female; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D008875:Middle Aged; D009062:Mouth Neoplasms / Q000737:chemistry / Q000175:diagnosis*; D055815:Young Adult
chemical_list: D002794:Choline