Uncertainties in determination of 131I activity in thyroid gland.
The values of the iodine 131I uptake determined from the measurements with a NaI scintillation counter might be significantly influenced by the thyroid position in the human neck. It is shown that the ratio of the counting rate in the energy peak of 364 keV to the counting rate in the Compton scattering band can be used for the determination of the effective depth of the thyroid. The uncertainties of the standard method are discussed basing on results of calibration measurements. The investigations of 95 patients with different thyroid diseases showed that the measured iodine spectrum was considerably different from the standard for about 20% of them, indicating possible high uncertainties of the standard measurements, which assume a fixed thyroid depth of 20 mm.
Ośko
Jakub
J
Institute of Atomic Energy, PL 05-400 Otwock-Swierk, Poland. j.osko@mchtr.pw.edu.pl
Golnik
Natalia
N
Pliszczynski
Tomasz
T
D000465:Algorithms; D001681:Biological Assay / Q000379:methods*; D003198:Computer Simulation; D004781:Environmental Exposure / Q000032:analysis*; D006801:Humans; D038622:Internationality; D007457:Iodine Radioisotopes / Q000032:analysis / Q000493:pharmacokinetics*; D008954:Models, Biological; D011829:Radiation Dosage; D011834:Radiation Monitoring / Q000379:methods*; D011835:Radiation Protection / Q000379:methods*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013961:Thyroid Gland / Q000378:metabolism*
D007457:Iodine Radioisotopes