title: [Status epilepticus and gatifloxacin].
abstract: BACKGROUND
  The epileptogenic potential of quinolones differs from one product to the other. The rare epileptic seizures induced by gatifloxacin were seen with the intravenous route.
  
  
  METHODS
  We report two old ladies presenting with generalized status epilepticus after being treated orally with normal doses of gatifloxacin, with a good recovery. Past medical history of convulsion was the only factor found. Brain MR imaging was unremarkable. In one patient, EEG showed continuous bilateral paroxysmal discharges, predominantly frontal.
  
  
  CONCLUSIONS
  Caution is warranted when using quinolones in elderly patients, especially those suffering from epilepsy.
authors.affiliation: Service de Neurologie, Hôpital Hôtel-Dieu de France, Université Saint-Joseph, Beyrouth, Liban. koussalam@hotmail.com
authors.forename: S
authors.initials: S
authors.lastname: Koussa
authors.forename: S
authors.initials: S
authors.lastname: Hage Chahine
authors.forename: A
authors.initials: A
authors.lastname: Zoghbi
authors.forename: P
authors.initials: P
authors.lastname: Yazbeck
mesh_terms: D000368:Aged; D000890:Anti-Infective Agents / Q000009:adverse effects*; D005260:Female; D024841:Fluoroquinolones / Q000009:adverse effects*; D000077734:Gatifloxacin; D006801:Humans; D013226:Status Epilepticus / Q000139:chemically induced*
chemical_list: D000890:Anti-Infective Agents; D024841:Fluoroquinolones; D000077734:Gatifloxacin