title: A case of common variable immunodeficiency syndrome associated with Takayasu arteritis.
abstract: BACKGROUND
  Association of common variable immunodeficiency (CVID) with Takayasu arteritis has rarely been reported.
  
  
  OBJECTIVE
  To describe a case of Takayasu arteritis in a 53-year-old Hispanic woman with CVID undergoing long-term (3-year) intravenous immunoglobulin (IVIG) treatment.
  
  
  METHODS
  The patient's serum immunoglobulin levels and antibody titers to measles, mumps, and rubella were measured. She also underwent angiography of the large vessels.
  
  
  RESULTS
  Low to undetectable serum IgA, IgM, and IgG levels and low antibody titers to mumps, measles, and rubella were consistent with the diagnosis of CVID. The angiogram showed narrowing of the proximal left subclavian artery (2-3 mm in diameter).
  
  
  CONCLUSIONS
  This patient developed Takayasu arteritis while receiving IVIG for CVID. She clinically improved after her IVIG dose was increased. To our knowledge, this is the second reported case of Takayasu arteritis associated with CVID.
authors.affiliation: Allergy/Immunology Division, Albert Einstein College of Medicine, Bronx, New York 10461, USA. ejerschow@yahoo.com
authors.forename: Elina
authors.initials: E
authors.lastname: Jerschow
authors.forename: Gabriele S
authors.initials: GS
authors.lastname: De Vos
authors.forename: Golda
authors.initials: G
authors.lastname: Hudes
authors.forename: Arye
authors.initials: A
authors.lastname: Rubinstein
authors.forename: Evan C
authors.initials: EC
authors.lastname: Lipsitz
authors.forename: David
authors.initials: D
authors.lastname: Rosenstreich
mesh_terms: D017074:Common Variable Immunodeficiency / Q000150:complications / Q000628:therapy*; D005260:Female; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use*; D008875:Middle Aged; D013625:Takayasu Arteritis / Q000150:complications / Q000628:therapy*
chemical_list: D016756:Immunoglobulins, Intravenous