title: Hg(OAc)(2).0.1Sc(OTf)(3)-catalyzed cycloisomerization of 2-(4-pentynyl)furan.
abstract: [structure: see text]. Although the Hg(OTf)2.3TMU-catalyzed Friedel-Crafts-type reaction of 3-(4-pentynyl)furan afforded the exo cyclization product, the reaction of 2-(4-pentynyl)furan furnished a very low yield. We found a 10:1 mixed reagent of Hg(OAc)2 and Sc(OTf)3 showed remarkable catalytic activity for the latter transformation. The actual reacting species is presumed to be Hg(OAc)(OTf), which is efficiently generated in situ by mixing the two reagents.
authors.affiliation: Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Tokushima, Japan.
authors.forename: Hirofumi
authors.initials: H
authors.lastname: Yamamoto
authors.forename: Ikuo
authors.initials: I
authors.lastname: Sasaki
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Imagawa
authors.forename: Mugio
authors.initials: M
authors.lastname: Nishizawa