title: [Comparison of atypical orofacial pain and temporomandibular disorders synovitis pain processing in the human brain using functional magnetic resonance imaging].
abstract: OBJECTIVE
  To compare the central nervous system processing of orofacial pain patients who might have atypical pain (group 1) after occlusal treatment with those patients who had synovitis pain of temporomandibular disorders (TMD) (group 2).
  
  
  METHODS
  Seven patients in each group were included in this study. Ten painless normal subjects (group 3) were employed as a control group. Functional magnetic resonance imaging (fMRI) was used to observe the activation of the brain evoked by clenching. The fMRI data were treated statistically as the result of each group.
  
  
  RESULTS
  The main active regions of three groups were different. The main active regions of the group 1 were bilateral thalamus and anterior cingulate cortex. The group 2 activated a quite different pain network, including postcentral gyrus, cingulate gyrus and prefrontal cortices.
  
  
  CONCLUSIONS
  The pain network is different between the two groups of pain patients and the pain network is more sensitive in atypical pain patients than in synovitis pain patients.
authors.affiliation: Department of Prosthodontics, Peking University School and Hospital of Stomatology, Beijing 100081, China. janqi@263.net
authors.forename: Ting
authors.initials: T
authors.lastname: Jiang
authors.forename: Jian
authors.initials: J
authors.lastname: Li
authors.forename: Zhen
authors.initials: Z
authors.lastname: Jin
authors.forename: Yu-wei
authors.initials: YW
authors.lastname: Wang
authors.forename: Hai-lan
authors.initials: HL
authors.lastname: Feng
authors.forename: Tatsuya
authors.initials: T
authors.lastname: Ishikawa
mesh_terms: D000328:Adult; D001921:Brain / Q000503:physiopathology*; D003793:Dental Restoration, Permanent / Q000009:adverse effects / Q000523:psychology*; D003830:Denture, Partial, Fixed / Q000009:adverse effects / Q000523:psychology*; D005157:Facial Pain / Q000209:etiology / Q000503:physiopathology*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D013705:Temporomandibular Joint Disorders / Q000209:etiology / Q000503:physiopathology*