title: Reference urodynamic values for stress incontinent women.
abstract: OBJECTIVE
  To determine reference urodynamic values for preoperative urodynamic studies in women undergoing surgery for pure or predominant stress urinary incontinence (SUI).
  
  
  METHODS
  Six hundred fifty-five women with pure or predominant SUI were enrolled in a multicenter surgical trial and were randomized to undergo a Burch or autologous fascia sling procedure as part of the Urinary Incontinence Treatment Network (UITN) Stress Incontinence Surgical Treatment Efficacy Trial (SISTEr). Preoperative free uroflowmetry, filling cystometry, and pressure flow studies were performed in all women using a standardized research protocol and standardized urodynamic interpretation guidelines. We define the normal range of urodynamic values in this population as the values that encompass 95% of the results.
  
  
  RESULTS
  In 655 women undergoing filling cystometry in the standing position, baseline vesical and abdominal pressures were between 12 and 60 cm H(2)O. The upper limit of detrusor pressure increase during bladder filling to maximum cystometric capacity was 16 cm H(2)O. Ten percent of women who qualified for stress incontinence surgery with a positive cough stress test on physical exam did not demonstrate urodynamic stress incontinence (USI) and less than 10% of subjects in this study demonstrated detrusor overactivity.
  
  
  CONCLUSIONS
  Results from a large cohort of women with SUI are now available for quantitative plausibility assessments or as reference values when interpreting urodynamic studies.
authors.affiliation: UCSD Women's Pelvic Medicine Center, La Jolla, California. cnager@ucsd.edu
authors.forename: C W
authors.initials: CW
authors.lastname: Nager
authors.forename: M E
authors.initials: ME
authors.lastname: Albo
authors.forename: M P
authors.initials: MP
authors.lastname: Fitzgerald
authors.forename: S
authors.initials: S
authors.lastname: McDermott
authors.forename: L
authors.initials: L
authors.lastname: Wruck
authors.forename: S
authors.initials: S
authors.lastname: Kraus
authors.forename: N
authors.initials: N
authors.lastname: Howden
authors.forename: P
authors.initials: P
authors.lastname: Norton
authors.forename: L
authors.initials: L
authors.lastname: Sirls
authors.forename: E
authors.initials: E
authors.lastname: Varner
authors.forename: P
authors.initials: P
authors.lastname: Zimmern
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003950:Diagnostic Techniques, Urological / Q000592:standards*; D005260:Female; D006801:Humans; D008875:Middle Aged; D017410:Practice Guidelines as Topic / Q000592:standards; D011300:Preoperative Care / Q000592:standards*; D011312:Pressure; D011786:Quality Control; D012016:Reference Values; D014550:Urinary Incontinence, Stress / Q000175:diagnosis* / Q000503:physiopathology / Q000601:surgery*; D014563:Urodynamics; D013520:Urologic Surgical Procedures / Q000379:methods*