title: Physiological MR signal variations within the brain at 3 T.
abstract: The echoplanar technique in magnetic resonance (MR) imaging allows the acquisition of a series of images from a selected slice with a temporal resolution of 10/s. Simultaneous recording of physiological information on pulse and respiration allows correlation of the MR signal intensity with physiological signals, which can be obtained for each pixel examined. Such correlations can be found within the cerebrospinal fluid (CSF) spaces and within vessels if a flow-sensitive MR measurement technique is used. The use of an MR scanner with a field strength of 3 T improves the signal/noise ratio, but there is a stronger signal decay due to local magnetic inhomogeneities. This study shows that 3-T systems can be used for correlation of MR and physiological signals and that clear differentiation between signals from CSF and from vessels can be obtained due to their strongly different signal decays.
authors.affiliation: Section for Experimental Magnetic Resonance of the Central Nervous System, Department for Neuroradiology, University Hospital Tübingen, Tübingen, Germany. uwe.klose@med.uni-tuebingen.de
authors.forename: Uwe
authors.initials: U
authors.lastname: Klose
authors.forename: Sigrid
authors.initials: S
authors.lastname: Friese
authors.forename: Michael
authors.initials: M
authors.lastname: Erb
authors.forename: Wolfgang
authors.initials: W
authors.lastname: Grodd
mesh_terms: D000465:Algorithms; D016477:Artifacts; D001921:Brain / Q000033:anatomy & histology* / Q000502:physiology*; D001931:Brain Mapping / Q000379:methods*; D017352:Echo-Planar Imaging / Q000379:methods*; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity