title: [The effectiveness of deep brain stimulation with intraoperative spatial mapping of subthalamic nucleus using intraoperative microrecording. Report of two cases].
abstract: The aims of the study were to present the surgical technique of bilateral subthalamic nucleus (STN) deep brain stimulation (DBS) and to analyze our experience with the MedtronicStealthStation Treon neuronavigation system and Framelink 4.1 software in targeting STN using single-unit extracellular action potentials (microrecording). The prospective study included 2 patients with bilateral STN DBS. The STN boundaries were mapped using microrecording, without microstimulation and recording of kinesthetic cells. For macrostimulation the longest trajectory with neuronal activity characteristic of STN was chosen. The patients were assessed using Unified Parkinson's Disease Rating Scale UPDRS version 3 and Schwab and England Scale. Postoperatively we did not notice intracerebral haemorrhage. Also there were no transient or permanent side effects. The mean number of microelectrode tracts was 4 per STN. Framelink 4.1 software is reliable to plan individual microelectrode trajectories and help avoid the intraparenchymal vessels.
authors.affiliation: Klinika Neurochirurgii, Centrum Medycznego Kształcenia Podyplomowego w Warszawie, Warszawa. mrsob@op.pl
authors.forename: Michał
authors.initials: M
authors.lastname: Sobstyl
authors.forename: Sebastian
authors.initials: S
authors.lastname: Dzierzecki
authors.forename: Mirosław
authors.initials: M
authors.lastname: Zabek
authors.forename: Henryk
authors.initials: H
authors.lastname: Koziara
authors.forename: Bartosz
authors.initials: B
authors.lastname: Kadziołka
authors.forename: Zbigniew
authors.initials: Z
authors.lastname: Mossakowski
mesh_terms: D000328:Adult; D046690:Deep Brain Stimulation / Q000379:methods*; D006801:Humans; D007430:Intraoperative Care; D008297:Male; D008875:Middle Aged; D010300:Parkinson Disease / Q000628:therapy*; D020531:Subthalamic Nucleus / Q000503:physiopathology / Q000601:surgery*; D016896:Treatment Outcome