title: Medical management of a corneal stromal abscess in a female Asian elephant (Elephas maximus).
abstract: A 47-yr-old female Asian elephant (Elephas maximus) developed a corneal stromal abscess in her right eye. The elephant was trained to open her eye for topical ophthalmic therapy, and was treated six times daily with antibiotics and an antifungal solution for almost 2 mo. Nonsteroidal anti-inflammatory drugs were used to control pain, and atropine was applied topically to dilate the pupil and provide additional comfort. Vascularization of the abscess began shortly after initiating therapy, and complete resolution was obtained by 7 wk.
authors.affiliation: Ringling Bros. and Barnum and Bailey Center for Elephant Conservation, Polk City, Florida 33868, USA.
authors.forename: Ellen B
authors.initials: EB
authors.lastname: Wiedner
authors.forename: Ramiro
authors.initials: R
authors.lastname: Isaza
authors.forename: Laurence E
authors.initials: LE
authors.lastname: Galle
authors.forename: Kathleen
authors.initials: K
authors.lastname: Barrie
authors.forename: William A
authors.initials: WA
authors.lastname: Lindsay
mesh_terms: D000038:Abscess / Q000188:drug therapy / Q000662:veterinary*; D000818:Animals; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use*; D000935:Antifungal Agents / Q000627:therapeutic use*; D003319:Corneal Stroma / Q000187:drug effects / Q000382:microbiology*; D004606:Elephants; D005260:Female; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents; D000894:Anti-Inflammatory Agents, Non-Steroidal; D000935:Antifungal Agents