Solvothermal in situ metal/ligand reactions: a new bridge between coordination chemistry and organic synthetic chemistry.
Several important solvothermal (including hydrothermal) in situ metal/ligand reactions and their mechanisms, including dehydrogenative carbon-carbon coupling, hydroxylation of aromatic rings, cycloaddition of organic nitriles with azide and ammonia, transformation of inorganic and organic sulfur, as well as the CuII to CuI reduction, are outlined in this Account. The current progress clearly demonstrates the important potential of such reactions in the crystal engineering of functional coordination compounds and one-pot synthesis of some unusual organic ligands that are inaccessible or not easily obtainable via conventional methods, thereby substantiating our expectation that a new bridge has been created between coordination chemistry and synthetic organic chemistry.
Chen
Xiao-Ming
XM
MOE Key Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry and Chemical Engineering, Sun Yat-Sen University, Guangzhou 510275, China. cxm@mail.sysu.edu.cn
Tong
Ming-Liang
ML
D000641:Ammonia / Q000737:chemistry; D001386:Azides / Q000737:chemistry; D002244:Carbon / Q000737:chemistry; D002625:Chemistry, Organic / Q000379:methods*; D003300:Copper / Q000737:chemistry; D003500:Cyclization; D006841:Hydrocarbons, Aromatic / Q000737:chemistry; D006900:Hydroxylation; D008024:Ligands; D008670:Metals / Q000737:chemistry*; D008956:Models, Chemical; D009570:Nitriles / Q000737:chemistry; D009930:Organic Chemicals / Q000138:chemical synthesis*; D009942:Organometallic Compounds / Q000737:chemistry; D010084:Oxidation-Reduction; D012997:Solvents / Q000737:chemistry*; D013455:Sulfur / Q000737:chemistry; D013696:Temperature
D001386:Azides; D006841:Hydrocarbons, Aromatic; D008024:Ligands; D008670:Metals; D009570:Nitriles; D009930:Organic Chemicals; D009942:Organometallic Compounds; D012997:Solvents; D013455:Sulfur; D002244:Carbon; D000641:Ammonia; D003300:Copper