title: Pigmentary changes and atopic dermatitis in a patient with Seckel syndrome.
abstract: Seckel syndrome is a very rare form of primordial dwarfism characterized by antenatal and postnatal growth delay, proportionate extreme short stature, a prominent beak-like nose, hypoplasia of the malar area, small chin, microcephaly, deformed ears lacking lobules, skeletal malformations, mental retardation, and developmental delay. This syndrome has been described with associated disorders of orthopedic, neurologic, hematologic, cardiac, and ocular systems; however, only a few reports mention dermatologic involvement. We describe a 5-year-old girl with classic Seckel syndrome who presented with moderately severe atopic dermatitis and diffuse hypopigmented macules and papules.
authors.affiliation: Texas Tech Health Sciences Center, Department of Dermatology, 3601 4th Street STOP 9400, Lubbock, TX 79430, USA.
authors.forename: Amy
authors.initials: A
authors.lastname: Brackeen
authors.forename: Michelle
authors.initials: M
authors.lastname: Babb-Tarbox
authors.forename: Jennifer
authors.initials: J
authors.lastname: Smith
mesh_terms: D000015:Abnormalities, Multiple; D002675:Child, Preschool; D019465:Craniofacial Abnormalities; D003876:Dermatitis, Atopic / Q000150:complications*; D004392:Dwarfism / Q000150:complications*; D005260:Female; D006801:Humans; D010859:Pigmentation Disorders / Q000150:complications*; D013577:Syndrome