The effect of diet on endothelial function.
Endothelial dysfunction is an early precursor to atherosclerosis. Lifestyle interventions, including diet, have been shown to affect endothelial function. High-fat diets have been shown to impair endothelial function, and diets such as the Mediterranean diet have been associated with improved endothelial function. This review discusses the effects of diet, dietary supplements such as folic acid, polyphenols, and antioxidant vitamins on endothelial function. We provide a summary of the current data linking diet with endothelial function and explore controversies within this field.
Davis
Nichola
N
Department of Medicine, Division of General Internal Medicine, Albert Einstein College of Medicine/Montefiore Medical Center, Bronx, NY, USA. ndavis@montefiore.org
Katz
Stuart
S
Wylie-Rosett
Judith
J
D000975:Antioxidants / Q000502:physiology; D050197:Atherosclerosis / Q000178:diet therapy / Q000517:prevention & control; D004032:Diet; D038441:Diet, Mediterranean; D004041:Dietary Fats / Q000378:metabolism; D004730:Endothelium, Vascular / Q000378:metabolism / Q000502:physiology* / Q000503:physiopathology; D005492:Folic Acid / Q000502:physiology; D005638:Fruit; D006710:Homocysteine / Q000502:physiology; D006801:Humans; D010636:Phenols / Q000378:metabolism; D012307:Risk Factors; D014675:Vegetables
D000975:Antioxidants; D004041:Dietary Fats; D010636:Phenols; D006710:Homocysteine; D005492:Folic Acid