Computing the center of mass for traveling alpha waves in the human brain.
The phenomenon of traveling waves of the brain is an intriguing area of research, and its mechanisms and neurobiological bases have been unknown since the 1950s. The present study offers a new method to compute traveling alpha waves using the center of mass algorithm. Electroencephalographic alpha waves are oscillations with a characteristic frequency range and reactivity to closed eyes. Several lines of evidence derived from qualitative observations suggest that the alpha waves represent a spreading wave process with specific trajectories in the human brain. We found that during a certain alpha wave peak recorded with 30 electrodes the trajectory starts and ends in distinct regions of the brain, mostly frontal-occipital, frontal-frontal, or occipital-frontal, but the position of the trajectory at the time in which the maximal positivity of the alpha wave occurs has a definite position near the central regions. Thus we observed that the trajectory always crossed around the central zones, traveling from one region to another region of the brain. A similar trajectory pattern was observed for different alpha wave peaks in one alpha burst, and in different subjects, with a mean velocity of 2.1+/-0.29 m/s. We found that all our results were clear and reproducible in all of the subjects. To our knowledge, the present method documents the first explicit description of a spreading wave process with a singular pattern in the human brain in terms of the center of mass algorithm.
Manjarrez
Elías
E
Instituto de Fisiología, Benemérita Universidad Autónoma de Puebla, 14 Sur 6301, Col. San Manuel, Apartado Postal 406, Puebla, Pue. CP 72570, Mexico. emanjar@siu.buap.mx
Vázquez
Montserrat
M
Flores
Amira
A
D000200:Action Potentials / Q000502:physiology; D000328:Adult; D000465:Algorithms; D000513:Alpha Rhythm / Q000295:instrumentation / Q000379:methods*; D001921:Brain / Q000033:anatomy & histology / Q000502:physiology*; D001931:Brain Mapping / Q000295:instrumentation / Q000379:methods; D002540:Cerebral Cortex / Q000033:anatomy & histology / Q000502:physiology; D003198:Computer Simulation; D004566:Electrodes / Q000592:standards; D005260:Female; D007839:Functional Laterality / Q000502:physiology; D006801:Humans; D008297:Male; D009434:Neural Pathways / Q000033:anatomy & histology / Q000502:physiology; D009474:Neurons / Q000502:physiology