title: Myasthenia gravis presenting with unusual neurogenic muscle atrophy.
abstract: We report a patient with myasthenia gravis who had neurogenic muscle atrophy in association with external ophthalmoplegia and weakness of the upper limbs. Neurogenic changes in the limb muscles were found on needle electromyography and histological studies. Symptoms improved and atrophy of the limbs diminished after intravenous immunoglobulin and oral corticosteroid therapy. We concluded that functional interruption of the neuromuscular junction caused the neurogenic muscle atrophy and that this was relieved by appropriate therapy.
authors.affiliation: Department of Neurology and Neurobiology of Aging, Kanazawa University Graduate School of Medical Science, 13-1, Takaramachi, Kanazawa, Ishikawa 920-8640, Japan. kimiharu@med.kanazawa-u.ac.jp
authors.forename: Miharu
authors.initials: M
authors.lastname: Samuraki
authors.forename: Eisuke
authors.initials: E
authors.lastname: Furui
authors.forename: Kiyonobu
authors.initials: K
authors.lastname: Komai
authors.forename: Masaharu
authors.initials: M
authors.lastname: Takamori
authors.forename: Masahito
authors.initials: M
authors.lastname: Yamada
mesh_terms: D000328:Adult; D004576:Electromyography; D006801:Humans; D008297:Male; D009133:Muscular Atrophy / Q000175:diagnosis* / Q000209:etiology / Q000473:pathology; D009157:Myasthenia Gravis / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D009886:Ophthalmoplegia / Q000175:diagnosis* / Q000209:etiology / Q000473:pathology