Image fusion-guided stereotactic iodine-125 interstitial irradiation of inoperable and recurrent gliomas.
Between 1996 and 2004, 27 patients with low grade gliomas (WHO grade I-II), 10 patients with WHO grade III gliomas and 6 patients with glioblastoma multiforme (WHO grade IV) were treated with stereotactic brachytherapy using low-dose rate iodine-125 (125I) isotope seeds at the Department of Neurosurgery, St. John's Hospital, Budapest, Hungary. In all 43 cases, brachytherapy was used for surgically inoperable gliomas: in 32 cases for recurrent gliomas and in 11 cases as a primary treatment. Results of this study suggest that 125I brachytherapy for inoperable and recurrent gliomas is an effective method and offers a chance for longer-term survival.
Julow
Jenö
J
Department of Neurosurgery, St. John's Hospital, Semmelweis University, Budapest, Hungary.
Viola
Árpád
Á
Bálint
Katalin
K
Szeifert
György T
GT
D000293:Adolescent; D000328:Adult; D000368:Aged; D001918:Brachytherapy; D001932:Brain Neoplasms / Q000401:mortality / Q000473:pathology* / Q000532:radiotherapy / Q000601:surgery*; D002648:Child; D005909:Glioblastoma / Q000401:mortality / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery; D005910:Glioma / Q000401:mortality / Q000473:pathology* / Q000532:radiotherapy / Q000601:surgery*; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D016634:Radiosurgery; D012189:Retrospective Studies; D015996:Survival Rate