title: [Effect of periodontitis on circulating C-reactive protein in type 2 diabetes patients].
abstract: OBJECTIVE
  To investigate the effect of periodontal infection on circulating C-reactive protein (CRP) in type 2 diabetes patients.
  
  
  METHODS
  32 diabetes patients with advanced periodontitis participated in this study. They were compared to a group of 32 diabetes patients without periodontal disease, who were mathed with regard to age (+/- 3 years), gender and body mass index (+/- 1 kg/m2). The concentration of CRP on circulation was measured by ELISA.
  
  
  RESULTS
  Significant difference was found in the level of CRP and the percentage of subjects with elevated CRP levels > or = 3 mg/L on circulation between the two groups(P < 0.05).
  
  
  CONCLUSIONS
  Periodontal infection results in higher circulating CRP in type 2 diabetes patients. This elevated inflammatory factor may exacerbate insulin resistance and increase the risk for great vessels complications of diabetes mellitus.
authors.affiliation: Dept. of Stomatology, The First Hospital of Hebei Medical University, Shijiazhuang 050031, China.
authors.forename: Yu-Xin
authors.initials: YX
authors.lastname: Gu
authors.forename: Qing-Xing
authors.initials: QX
authors.lastname: Li
authors.forename: Yan-Ling
authors.initials: YL
authors.lastname: You
authors.forename: Guang-Shun
authors.initials: GS
authors.lastname: Liu
authors.forename: Xu
authors.initials: X
authors.lastname: Han
mesh_terms: D000328:Adult; D002097:C-Reactive Protein; D003924:Diabetes Mellitus, Type 2; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D017622:Periodontal Attachment Loss; D010514:Periodontal Pocket; D010518:Periodontitis
chemical_list: D002097:C-Reactive Protein