Viscosity is not a parameter of postdeglutitive pharyngeal residue: quantification and analysis with scintigraphy.
The aim of this study was to explore the influence of viscosity on pharyngeal residue in normal healthy volunteers. Scintigraphy was used to measure pharyngeal residue in 11 healthy volunteers after swallowing three different substances (age = 20.2-48.3 years). The first substance was a 10-ml solution of tap water with 0.5% xanthan with a viscosity of 4500 mPa s, comparable to a yogurt drink. The second and third substances were a 0.75% xanthan and a 1.00% xanthan solution, with viscosities of 10,500 and 21,000 mPa s, comparable to low-fat yogurt and 3% fat yogurt, respectively. Tap water was used as the control substance. Mean pharyngeal residue after swallowing tap water was 2.3% (SD = 1.2) of the initial volume in the oral cavity. Pharyngeal residue after swallowing 0.5% xanthan solution was 1.8% (SD = 0.8), after swallowing 0.75% xanthan solution 2.6% (SD = 2.2), and after swallowing 1.00% xanthan solution 2.8% (SD = 1.7). No significant correlation between increase of viscosity and pharyngeal residue was found. In healthy persons viscosity does not seem to be a significant parameter for pharyngeal residue for boluses with viscosities ranging from tap water to solutions having a viscosity comparable to 3% fat yogurt.
Bogaardt
H C A
HC
Department of Otolaryngology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands. h.c.bogaardt@amc.uva.nl
Burger
J J
JJ
Fokkens
W J
WJ
Bennink
R J
RJ
D000328:Adult; D003679:Deglutition / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010614:Pharynx / Q000502:physiology*; D011135:Polysaccharides, Bacterial / Q000737:chemistry; D011446:Prospective Studies; D011877:Radionuclide Imaging; D013997:Time Factors; D014783:Viscosity; D014867:Water / Q000737:chemistry
D011135:Polysaccharides, Bacterial; D014867:Water; C002563:xanthan gum