title: Carotid duplex ultrasonography during head-up tilt in patients with orthostatic hypotension.
abstract: Orthostatic hypotension (OH) is defined by evaluating postural blood pressure (BP) change, but the correlation between postural BP decreases and OH-associated symptoms is poor. We examined carotid duplex ultrasonography during HUT in 27 patients with various neurological disorders. Nine patients were diagnosed to have OH, and 4 of them had symptoms associated with OH. Decreased end-diastolic velocity of common carotid artery in symptomatic OH patients (-24.5 +/- 4.2 cm/s) was significantly larger than that in asymptomatic OH patients (-11.0 +/- 8.0 cm/s; p = 0.0143), despite no significant differences in values and changes of BP between them. This may be useful for predicting the development of OH symptoms.
authors.affiliation: Department of Neurology and Neurobiology of Aging, Kanazawa University Graduate School of Medical Science, Kanazawa, Japan. gom56@ipch.jp
authors.forename: Tsuyoshi
authors.initials: T
authors.lastname: Hamaguchi
authors.forename: Kazuo
authors.initials: K
authors.lastname: Iwasa
authors.forename: Soichi
authors.initials: S
authors.lastname: Okino
authors.forename: Masahito
authors.initials: M
authors.lastname: Yamada
mesh_terms: D000328:Adult; D000368:Aged; D001783:Blood Flow Velocity; D001794:Blood Pressure; D017536:Carotid Artery, Common / Q000000981:diagnostic imaging*; D003971:Diastole; D005260:Female; D018475:Head-Down Tilt; D006339:Heart Rate; D006801:Humans; D007024:Hypotension, Orthostatic / Q000175:diagnosis / Q000000981:diagnostic imaging* / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D011187:Posture; D013599:Systole; D018616:Ultrasonography, Doppler, Duplex