An overview of non-cardiac cocaine toxicity.
Cocaine use in the United States continues to be a significant problem. Cocaine use is responsible for approximately 143,000 Emergency Department visits annually. The cardiac effects of cocaine are well known and much is written on this topic; this is beyond the scope of this article. Cocaine use is also responsible for a variety of non-cardiac, systemic complications, which it is our purpose to review. Multiple systemic effects of cocaine are seen with both acute and chronic use. These systems include: psychological and psychiatric, neurological, renal, pulmonary, gastrointestinal, obstetrical, and otolaryngological.
Glauser
Jonathan
J
Department of Emergency Medicine, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA.
Queen
John R
JR
D002490:Central Nervous System / Q000187:drug effects; D003042:Cocaine / Q000009:adverse effects*; D019970:Cocaine-Related Disorders / Q000503:physiopathology* / Q000523:psychology*; D018765:Dopamine Uptake Inhibitors / Q000009:adverse effects*; D005315:Fetal Diseases / Q000139:chemically induced; D006801:Humans; D008171:Lung Diseases / Q000139:chemically induced; D009300:Nasal Septum / Q000187:drug effects / Q000473:pathology; D051437:Renal Insufficiency / Q000139:chemically induced
D018765:Dopamine Uptake Inhibitors; D003042:Cocaine