title: Mitochondrial DNA population data of HVS-I and HVS-II sequences from a northeast German sample.
abstract: Mitochondrial DNA sequences of the control region's two hypervariable regions HVS-I and HVS-II were determined for 213 unrelated west Eurasian individuals from northeast Germany (Mecklenburg). A total of 174 different mtDNA haplotypes were found, 25 of which were shared by more than 1 individual. The most frequent haplotypes were 263G-309.1C-315.1C, found in seven individuals, 263G-309.1C-309.2C-315.1C, found in six individuals and 263G-315.1C, found in five individuals. These sequences are also the most common haplotypes in other published European data sets. The sequence polymorphisms consisting of 150 polymorphic nucleotide positions were compared with other European databases. The genetic diversity and random match probability were calculated. Our results corroborate certain features which are characteristic for west Eurasian mtDNA population samples.
authors.affiliation: Institute of Legal Medicine, University of Rostock, Rostock, Germany.
authors.forename: Sylvio
authors.initials: S
authors.lastname: Tetzlaff
authors.forename: Anita
authors.initials: A
authors.lastname: Brandstätter
authors.forename: Rudolf
authors.initials: R
authors.lastname: Wegener
authors.forename: Walther
authors.initials: W
authors.lastname: Parson
authors.forename: Volker
authors.initials: V
authors.lastname: Weirich
mesh_terms: D022801:Complementarity Determining Regions / Q000235:genetics*; D004272:DNA, Mitochondrial / Q000235:genetics*; D030561:Databases, Nucleic Acid; D014644:Genetic Variation; D005858:Germany; D006239:Haplotypes; D006801:Humans; D017422:Sequence Analysis, DNA
chemical_list: D022801:Complementarity Determining Regions; D004272:DNA, Mitochondrial