title: Indoor environmental influences on children's asthma.
abstract: The burden of asthma for children in the United States is substantial and has continued to rise for the past 2 decades. There is growing evidence that the indoor environment may play an important role in the pathogenesis of childhood asthma. This article first reviews the effects of indoor allergen exposure and sensitization on asthma incidence and morbidity, focusing on dust mite, cockroach, pet, and rodent allergens. It then addresses the effects of indoor air pollutants (ozone, particulate matter, nitrogen dioxide, environmental tobacco smoke, sulfur dioxide, and carbon monoxide) on asthma morbidity.
authors.affiliation: Division of Allergy and Immunology, Department of Pediatrics, Johns Hopkins University School of Medicine, 600 North Wolfe Street, CMSC 1102, Baltimore, MD 21287, USA.
authors.forename: Hemant P
authors.initials: HP
authors.lastname: Sharma
authors.forename: Nadia N
authors.initials: NN
authors.lastname: Hansel
authors.forename: Elizabeth
authors.initials: E
authors.lastname: Matsui
authors.forename: Gregory B
authors.initials: GB
authors.lastname: Diette
authors.forename: Peyton
authors.initials: P
authors.lastname: Eggleston
authors.forename: Patrick
authors.initials: P
authors.lastname: Breysse
mesh_terms: D016902:Air Pollution, Indoor / Q000009:adverse effects*; D000818:Animals; D001249:Asthma / Q000453:epidemiology / Q000209:etiology* / Q000276:immunology; D002248:Carbon Monoxide / Q000009:adverse effects; D002415:Cats / Q000276:immunology; D002648:Child; D003058:Cockroaches / Q000276:immunology; D004285:Dogs / Q000276:immunology; D018876:Environmental Illness / Q000453:epidemiology / Q000209:etiology*; D006801:Humans; D009585:Nitrogen Dioxide / Q000009:adverse effects; D039981:Pyroglyphidae / Q000276:immunology; D012377:Rodentia / Q000276:immunology; D014028:Tobacco Smoke Pollution / Q000009:adverse effects
chemical_list: D014028:Tobacco Smoke Pollution; D002248:Carbon Monoxide; D009585:Nitrogen Dioxide