Congenital erythropoietic porphyria in an African hedgehog (Atelerix albiventris).
A 6-mo-old, male African hedgehog (Atelerix albiventris) presented with a history of pink urine and demonstrating pink-colored teeth and mild hepatomegaly on examination. Urinalysis revealed no physical, chemical, or cellular abnormalities other than a pink color and fluorescence under ultraviolet light (UV). Also under UV, intense fluorescence of teeth, feet, and spines was noted. Porphyria was suspected. Spectrophotometric evaluation of urine showed extremely elevated levels of copro- and uroporphyrins. Analysis of the urine by thin-layer chromatography showed an abnormal pattern of excreted porphyrin intermediates. Urine high-performance thin-layer chromatography showed that excreted porphyrins were 90-95% of the type-I isomeric form, suggestive of congenital erythropoietic porphyria.
Wolff
Carlos
C
Departamento de Medicina Occidente, Facultad de Medicina, Universidad de Chile, Chacabuco 419, 835 0429 Santiago, Chile.
Corradini
Paulina
P
Cortés
Galaxia
G
D000818:Animals; D002851:Chromatography, High Pressure Liquid / Q000662:veterinary; D003306:Coproporphyrins / Q000378:metabolism / Q000652:urine; D006364:Hedgehogs / Q000652:urine; D008297:Male; D017092:Porphyria, Erythropoietic / Q000175:diagnosis / Q000652:urine / Q000662:veterinary*; D011166:Porphyrins / Q000378:metabolism / Q000652:urine
D003306:Coproporphyrins; D011166:Porphyrins