Tenacibactins A-D, hydroxamate siderophores from a marine-derived bacterium, Tenacibaculum sp. A4K-17.
Four new hydroxamate siderophores, tenacibactins A-D (1-4), were isolated from a culture broth of the marine-derived bacterium Tenacibaculum sp. A4K-17. The structures of these tenacibactins were determined by NMR analyses and ESIMS/MS experiments. The iron-binding (chelating) activity of 1-4 was evaluated by the chrome azurol sulfonate (CAS) assay.
Jang
Jae-Hyuk
JH
Laboratory of Applied Bioorganic Chemistry, Marine Biotechnology Institute Co., Ltd., 3-75-1 Heita, Kamaishi, Iwate 026-0001, Japan. jang.jaehyuk@mbio.jp
Kanoh
Kaneo
K
Adachi
Kyoko
K
Matsuda
Satoru
S
Shizuri
Yoshikazu
Y
D041965:Flavobacteriaceae / Q000737:chemistry*; D006877:Hydroxamic Acids / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D062385:Hydroxybenzoates / Q000494:pharmacology; D007502:Iron Chelating Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D008386:Marine Biology; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D017262:Siderophores / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
D006877:Hydroxamic Acids; D062385:Hydroxybenzoates; D007502:Iron Chelating Agents; D017262:Siderophores; C015076:chrome azurol S