Efficient methodology for selective alkylation of hydrazine derivatives.
Formation and use of a nitrogen dianion for selective hydrazine alkylation is reported. The scope and limitations of a new method were demonstrated. The novel method provides fast and easy access to substituted hydrazines, which are widely used as drugs, pesticides, and precursors for a variety of compounds in organic synthesis. [reaction: see text]
Bredihhin
Aleksei
A
Institute of Organic and Bioorganic Chemistry, University of Tartu, Jakobi 2, 51014 Tartu, Estonia.
Groth
Ulrich M
UM
Mäeorg
Uno
U
D000478:Alkylation; D006834:Hydrazines / Q000737:chemistry*; D008956:Models, Chemical; D009584:Nitrogen / Q000737:chemistry
D006834:Hydrazines; C029424:hydrazine; D009584:Nitrogen