title: Changes in bone mineral and body composition following coronary artery bypass grafting in men.
abstract: This study investigated bone mineral and body composition changes after coronary artery bypass grafting (CABG) in men. Twenty-six men 50 to 79 years of age underwent CABG for multivessel coronary disease. Dual-energy x-ray absorptiometry was performed before surgery and 3 months and 1 year after treatment to assess bone mineral content (BMC), bone mineral density (BMD), and body composition. Through 3 months after treatment, BMD decreased at the total body, arms, and pelvis. BMC of the arm decreased and losses at the total body and legs approached significance. Fat-free mass decreased in the arms and total body but not in the legs. Neither total body nor regional fat mass changed. At the 1-year follow-up visit, 15 of the initial 26 subjects returned for dual-energy x-ray absorptiometry. Compared with before treatment, BMD decreased at the total body and legs, whereas losses at the arms approached significance. Arm BMC decreased over the 1-year post-treatment period. No changes were observed in body composition. In conclusion, CABG and the ensuing convalescence period results in considerable arm bone mineral losses through 1 year after treatment.
authors.affiliation: Department of Human Nutrition, Foods and Exercise, Virginia Polytechnic Institute and State University, Virginia, USA.
authors.forename: Larry E
authors.initials: LE
authors.lastname: Miller
authors.forename: Lee M
authors.initials: LM
authors.lastname: Pierson
authors.forename: Mary E
authors.initials: ME
authors.lastname: Pierson
authors.forename: Gary M
authors.initials: GM
authors.lastname: Kiebzak
authors.forename: Warren K
authors.initials: WK
authors.lastname: Ramp
authors.forename: William G
authors.initials: WG
authors.lastname: Herbert
authors.forename: Joseph W
authors.initials: JW
authors.lastname: Cook
mesh_terms: D000368:Aged; D001823:Body Composition; D015519:Bone Density; D003289:Convalescence; D001026:Coronary Artery Bypass; D003327:Coronary Disease / Q000503:physiopathology / Q000601:surgery*; D017079:Exercise Tolerance / Q000502:physiology; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D013997:Time Factors