Cytokinesis: LET-ting the asters signal.
Cytokinesis is regulated by both astral microtubules and the midzone microtubules of the mitotic apparatus. A new study in Caenorhabditis elegans has identified the polarity factor LET-99 and its heterotrimeric G-protein regulators as components of the signaling pathway downstream of astral microtubules.
Burgess
David R
DR
Biology Department, Boston College, 140 Commonwealth Avenue, Chestnut Hill, Massachusetts 02467, USA. David.burgess@bc.edu
D000818:Animals; D017173:Caenorhabditis elegans; D029742:Caenorhabditis elegans Proteins / Q000378:metabolism*; D048749:Cytokinesis / Q000502:physiology*; D019204:GTP-Binding Proteins / Q000378:metabolism*; D008870:Microtubules / Q000378:metabolism / Q000502:physiology*; D015398:Signal Transduction / Q000502:physiology*
D029742:Caenorhabditis elegans Proteins; C467518:LET-99 protein, C elegans; D019204:GTP-Binding Proteins