Tetracycline resistance in group a streptococci: emergence on a global scale and influence on multiple-drug resistance.
A global sample of group A streptococci (GAS) revealed > or =80 separate acquisitions of tetracycline resistance. Of 244 clones, 38 and 25% displayed resistance to tetracycline and erythromycin, respectively; a relatively high proportion (15%) were resistant to both classes of drugs. tet(M) displayed a highly significant association with erm(B).
Ayer
Vanessa
V
Department of Microbiology and Immunology, New York Medical College, Valhalla, NY 10595, USA.
Tewodros
Wezenet
W
Manoharan
Anand
A
Skariah
Sini
S
Luo
Feng
F
Bessen
Debra E
DE
D024901:Drug Resistance, Multiple, Bacterial; D010802:Phylogeny; D013297:Streptococcus pyogenes / Q000187:drug effects* / Q000235:genetics; D013753:Tetracycline Resistance