title: Gametocytemia in Plasmodium vivax and Plasmodium falciparum infections.
abstract: Two expert research microscopists, each blinded to the other's reports, diagnosed single-species malaria infections in 2,141 adults presenting at outpatient malaria clinics in Tak Province, Thailand, and Iquitos, Peru, in May-August 1998, May-July 1999, and May-June 2001. Plasmodium vivax patients with gametocytemia had higher fever and higher parasitemia than those without gametocytemia; temperature correlated with parasitemia in the patients with gametocytemia. Plasmodium falciparum patients with gametocytemia had lower fever than those without gametocytemia, but similar parasitemia; temperature correlated with parasitemia in the patients without gametocytemia. Hematologic data in Thailand in 2001 showed lower platelet counts in P. vivax patients with gametocytemia than in the P. vivax patients without gametocytemia, whereas P. falciparum patients with gametocytemia had similar platelet counts but lower red blood cell counts, hemoglobin levels, hematocrit levels, and higher lymphocyte counts than patients without gametocytemia.
authors.affiliation: Fogarty International Center, National Institutes of Health, Bethesda, Maryland 20892, USA. em225k@nih.gov
authors.forename: F Ellis
authors.initials: FE
authors.lastname: Mckenzie
authors.forename: Chansuda
authors.initials: C
authors.lastname: Wongsrichanalai
authors.forename: Alan J
authors.initials: AJ
authors.lastname: Magill
authors.forename: J Russ
authors.initials: JR
authors.lastname: Forney
authors.forename: Barnyen
authors.initials: B
authors.lastname: Permpanich
authors.forename: Carmen
authors.initials: C
authors.lastname: Lucas
authors.forename: Laura M
authors.initials: LM
authors.lastname: Erhart
authors.forename: Wendy P
authors.initials: WP
authors.lastname: O'Meara
authors.forename: David L
authors.initials: DL
authors.lastname: Smith
authors.forename: Jeeraphat
authors.initials: J
authors.lastname: Sirichaisinthop
authors.forename: Robert A
authors.initials: RA
authors.lastname: Gasser
mesh_terms: D000328:Adult; D000367:Age Factors; D000818:Animals; D003430:Cross-Sectional Studies; D019353:Endemic Diseases; D004906:Erythrocyte Count; D005260:Female; D005334:Fever; D006400:Hematocrit; D006454:Hemoglobins / Q000032:analysis; D006801:Humans; D007958:Leukocyte Count; D016778:Malaria, Falciparum / Q000453:epidemiology* / Q000469:parasitology; D016780:Malaria, Vivax / Q000453:epidemiology* / Q000469:parasitology; D008297:Male; D018512:Parasitemia / Q000453:epidemiology* / Q000469:parasitology; D010568:Peru / Q000453:epidemiology; D013785:Thailand / Q000453:epidemiology
chemical_list: D006454:Hemoglobins