title: Cronkhite-Canada syndrome associated with schizophrenia.
abstract: Here, we report a case of Cronkhite-Canada syndrome in a patient with schizophrenia. A 64-year-old man, who had been diagnosed as having a schizophrenic disorder at the age of 30, presented with alopecia, atrophic nail changes, hyperpigmentation of the skin, and inflammatory polyposis of the stomach and colon. Endoscopic ultrasonography of the stomach and colon revealed diffuse mucosal thickening with small hypoechoic areas, corresponding to edema of the lamina propria. After treatment with parenteral hyperalimentation and tranexamic acid, his physical findings and polyposis gradually improved. This is the first report of Cronkhite-Canada syndrome in a patient with schizophrenia.
authors.affiliation: Department of Advanced Molecular and Cell Therapy, Kyushu University Hospital, Fukuoka, Japan.
authors.forename: Masaharu
authors.initials: M
authors.lastname: Nakayama
authors.forename: Hiromi
authors.initials: H
authors.lastname: Muta
authors.forename: Shinichi
authors.initials: S
authors.lastname: Somada
authors.forename: Toyoki
authors.initials: T
authors.lastname: Maeda
authors.forename: Toshitaka
authors.initials: T
authors.lastname: Mutoh
authors.forename: Kanako
authors.initials: K
authors.lastname: Shimizu
authors.forename: Yoko
authors.initials: Y
authors.lastname: Suehiro
authors.forename: Terumasa
authors.initials: T
authors.lastname: Hisano
authors.forename: Ryo
authors.initials: R
authors.lastname: Kurita
authors.forename: Takeshi
authors.initials: T
authors.lastname: Shiraishi
authors.forename: Masaki
authors.initials: M
authors.lastname: Mori
authors.forename: Yasuji
authors.initials: Y
authors.lastname: Yoshikawa
authors.forename: Nobuto
authors.initials: N
authors.lastname: Tsunetomi
authors.forename: Akihiro
authors.initials: A
authors.lastname: Uchida
authors.forename: Kenzaburo
authors.initials: K
authors.lastname: Tani
mesh_terms: D000505:Alopecia / Q000175:diagnosis / Q000628:therapy; D003113:Colonoscopy; D003131:Combined Modality Therapy; D003967:Diarrhea / Q000175:diagnosis / Q000628:therapy; D019160:Endosonography / Q000379:methods; D005500:Follow-Up Studies; D006801:Humans; D017495:Hyperpigmentation / Q000175:diagnosis / Q000628:therapy; D044483:Intestinal Polyposis / Q000150:complications* / Q000175:diagnosis* / Q000628:therapy; D008297:Male; D008875:Middle Aged; D018570:Risk Assessment; D012559:Schizophrenia / Q000150:complications* / Q000175:diagnosis* / Q000628:therapy