Palladium-catalyzed C-P coupling reactions between vinyl triflates and phosphine-boranes: efficient access to vinylphosphine-boranes.
Vinylphosphine-borane complexes are easily synthesized by palladium-catalyzed C-P cross-coupling of vinyl triflates with secondary phosphine-boranes. This method allows the synthesis of phosphine derivatives not always easily accessible by other approaches. The vinylphosphine derivatives are purified by chromatography on silica gel. The versatility of the method is proved by using various triflates and diaryl-, dialkyl- and alkylarylphosphine-borane precursors. Chiral enantiopure phosphine-boranes are synthesized from chiral triflates.
Julienne
Delphine
D
Laboratoire de Chimie Moléculaire et Thioorganique, UMR CNRS 6507, ENSICAEN and Université de Caen, 14050 Caen, France.
Lohier
Jean-François
JF
Delacroix
Olivier
O
Gaumont
Annie-Claude
AC