title: [Changes of the triple flash electroretinogram after 360 degrees retinotomy and macular translocation for subfoveal choroidal neovascularisation in age-related macular degeneration].
abstract: BACKGROUND
  The aim of the present study was to evaluate potential electrophysiological changes after 360 degrees retinotomy and macular translocation for subfoveal choroidal neovascularisation in patients with age-related macular degeneration.
  
  
  METHODS
  A consecutive series of 32 patients suffering from subfoveal choroidal neovascularisation secondary to age-related macular degeneration underwent 360 degrees retinotomy and macular translocation. The scotopic triple-flash ERG (TERG) served as the main parameter of the study and was recorded one day prior to the translocation surgery and no earlier than 4 weeks after the silicone oil removal.
  
  
  RESULTS
  The TERG amplitudes were significantly reduced after translocation surgery. Depending on the applied flash luminance the mean amplitude reduction of the first b-wave varied between 67 % (0.2 cds/m (2)) and 74 % (0.03 cds/m (2)). The latency of the second b-wave of the preoperative TERG proved to have predictive power with reference to the postoperative visual acuity. A statistically significant correlation between the latency of the second b-wave for a flash intensity of 0.03 and 0.1 cds/m (2) and the postoperative visual acuity was shown (p = 0,016 and p = 0,049).
  
  
  CONCLUSIONS
  In accordance with previous studies the present study indicates that a significant electrophysiological decrease is caused by surgical procedures associated with macular translocation. In future, due to predictive parameters of the TERG the preoperative selection of patients could be improved.
authors.affiliation: Zentrum für Augenheilkunde der Universität Köln, ERG-Labor Joseph-Stelzmann-Strasse 9, 50924 Köln. aia18@uni-koeln.de
authors.forename: C
authors.initials: C
authors.lastname: Lüke
authors.forename: M
authors.initials: M
authors.lastname: Lüke
authors.forename: S
authors.initials: S
authors.lastname: Aisenbrey
authors.forename: T S
authors.initials: TS
authors.lastname: Dietlein
authors.forename: K U
authors.initials: KU
authors.lastname: Bartz-Schmidt
authors.forename: B
authors.initials: B
authors.lastname: Kirchhof
authors.forename: P
authors.initials: P
authors.lastname: Walter
mesh_terms: D000368:Aged; D004596:Electroretinography; D005260:Female; D005451:Fluorescein Angiography; D005500:Follow-Up Studies; D006801:Humans; D008266:Macula Lutea / Q000503:physiopathology / Q000601:surgery*; D008268:Macular Degeneration / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D013508:Ophthalmologic Surgical Procedures; D009887:Ophthalmoscopy; D010775:Photic Stimulation; D011183:Postoperative Complications / Q000209:etiology / Q000503:physiopathology*; D011930:Reaction Time / Q000502:physiology; D012160:Retina / Q000503:physiopathology / Q000601:surgery*; D013223:Statistics as Topic; D014792:Visual Acuity / Q000502:physiology