Surgical excision of mycotic (Cladosporium sp.) granulomas from the mantle of a cuttlefish (Sepia officinalis).
An adult female European cuttlefish (Sepia officinalis) from a public aquarium presented with an eruptive skin lesion of the dorsal mantle. Radiographs, hemolymph collection, and excisional biopsy were performed using anesthesia with ethanol 1.5-3% in seawater. Elastic and freely mobile skin permitted closure with minimal tension following wide excision around the lesions, which did not appear to penetrate deep to the underlying cuttlebone. Biopsy revealed hemocyte granulomas surrounding thin, septate, infrequently branching fungal hyphae, and culture yielded Cladosporium sp. Itraconazole was administered postoperatively in food items. The cuttlefish recovered to normal feeding and activity levels with complete surgical site healing. Two months following the procedure, the animal was found dead in exhibit. Histopathologic examination revealed multisystemic fungal infection.
Harms
Craig A
CA
North Carolina State University, College of Veterinary Medicine, Department of Clinical Sciences, Center for Marine Sciences and Technology, 303 College Circle, Morehead City, North Carolina 28557, USA.
Lewbart
Gregory A
GA
McAlarney
Ryan
R
Christian
Larry S
LS
Geissler
Kyleigh
K
Lemons
Carol
C
D000818:Animals; D000935:Antifungal Agents / Q000627:therapeutic use; D002963:Cladosporium / Q000302:isolation & purification*; D049832:Decapodiformes / Q000382:microbiology*; D003881:Dermatomycoses / Q000188:drug therapy / Q000601:surgery / Q000662:veterinary*; D017809:Fatal Outcome; D006099:Granuloma / Q000188:drug therapy / Q000382:microbiology / Q000601:surgery / Q000662:veterinary*; D017964:Itraconazole / Q000627:therapeutic use
D000935:Antifungal Agents; D017964:Itraconazole