title: 3-[(3-Dehydroabietamidopropyl)dimethylammonio]-1-propane-sulfonate as a new type of chiral surfactant for enantiomer separation in micellar electrokinetic chromatography.
abstract: A new type of chiral surfactant, 3-[(3-dehydroabietamidopropyl) dimethylammonio]-1-propanesulfonate (DHAMAP) has been synthesized. The ability of this compound to perform chiral separation of D/L-amino acids derivatized with naphthalene-2, 3-dicarboxaldehyde (NDA-D/L-amino acids) has been investigated by capillary electrophoresis (CE). Enantiomeric separation of NDA-D/L-amino acids was achieved with a running buffer consisting of 50 mM borate (pH 9.75) and 25 mM DHADMP. Under the conditions selected, 6 pairs of tested amino acids enantiomers including NDA-D/L-tryptophan, NDA-D/L-phenylalanine, D/L-D/L-kynurenine, NDA-D/L-beta-phenylalanine, NDA-D/L-4-methylphenylalanine and NDA-D/L-arginine were well resolved. The resolution values were in the range of 1.56-5.40.
authors.affiliation: College of Chemistry and Chemical Engineering, Guangxi Nomal University, Guilin 541004, China. zhaoshulin001@163.com
authors.forename: Shulin
authors.initials: S
authors.lastname: Zhao
authors.forename: Hengshan
authors.initials: H
authors.lastname: Wang
authors.forename: Yingming
authors.initials: Y
authors.lastname: Pan
authors.forename: Min
authors.initials: M
authors.lastname: He
authors.forename: Zhicai
authors.initials: Z
authors.lastname: Zhao
mesh_terms: D000476:Alkanesulfonates / Q000737:chemistry*; D020374:Chromatography, Micellar Electrokinetic Capillary / Q000379:methods*; D019075:Electrophoresis, Capillary / Q000379:methods; D015394:Molecular Structure; D015203:Reproducibility of Results; D013237:Stereoisomerism; D013501:Surface-Active Agents / Q000737:chemistry*
chemical_list: D000476:Alkanesulfonates; D013501:Surface-Active Agents