title: Successful mitral valve replacement in a patient with a severe form of beta-thalassaemia.
abstract: beta-Thalassaemia is an inherited haemoglobin (Hb) disorder resulting in chronic haemolytic anaemia. The most anaemic patients require regular red blood cell (RBC) transfusions for survival but iron accumulation leads to multisystem dysfunction. Heart complications represent the leading cause of mortality in beta-thalassaemia patients. In this case report we present a successful mitral valve replacement (MVR) in a patient with a severe form of beta-thalassaemia.
authors.affiliation: Department of Cardiac Surgery, University of Bologna, Bologna, Italy.
authors.forename: Luca
authors.initials: L
authors.lastname: Botta
authors.forename: Carlo
authors.initials: C
authors.lastname: Savini
authors.forename: Sofia
authors.initials: S
authors.lastname: Martin-Suarez
authors.forename: Andrea
authors.initials: A
authors.lastname: Dell' Amore
authors.forename: Nicola
authors.initials: N
authors.lastname: Camurri
authors.forename: Giorgio
authors.initials: G
authors.lastname: Arpesella
authors.forename: Roberto
authors.initials: R
authors.lastname: Di Bartolomeo
mesh_terms: D001803:Blood Transfusion; D005500:Follow-Up Studies; D019918:Heart Valve Prosthesis Implantation / Q000379:methods*; D006801:Humans; D008297:Male; D008875:Middle Aged; D008944:Mitral Valve Insufficiency / Q000175:diagnosis / Q000209:etiology* / Q000601:surgery*; D019990:Perioperative Care / Q000379:methods; D018570:Risk Assessment; D012720:Severity of Illness Index; D016896:Treatment Outcome; D017086:beta-Thalassemia / Q000150:complications* / Q000175:diagnosis