title: Transjugular intrahepatic portosystemic shunt for the treatment of portal hypertension due to idiopathic myelofibrosis.
abstract: A 59-year-old man was diagnosed to have idiopathic myelofibrosis (IMF) in November 2001. In April 2004, massive ascites and esophageal varices were found. IMF was considered to be the cause of portal hypertension (ascites and esophageal varices). Since ascites tend to be intractable with diuretic drugs, a transjugular intrahepatic portosystemic shunt (TIPS) was inserted in May 2004. Before TIPS, his waist measured 98 cm. On day 74 after TIPS, his waist measured 68 cm as a result of the administration of diuretic drugs alone. He eventually died due to hepatic failure on day 168 after TIPS. The autopsy findings suggest that sinusoidal fibrosis caused portal hypertension.
authors.affiliation: The Division of Hematology, Saiseikai Maebashi Hospital, Maebashi.
authors.forename: Noriko
authors.initials: N
authors.lastname: Doki
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Irisawa
authors.forename: Satoru
authors.initials: S
authors.lastname: Takada
authors.forename: Tohru
authors.initials: T
authors.lastname: Sakura
authors.forename: Shuichi
authors.initials: S
authors.lastname: Miyawaki
mesh_terms: D018450:Disease Progression; D017809:Fatal Outcome; D005355:Fibrosis / Q000150:complications / Q000473:pathology; D006529:Hepatomegaly / Q000150:complications / Q000473:pathology; D006801:Humans; D006975:Hypertension, Portal / Q000209:etiology* / Q000503:physiopathology / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D019168:Portasystemic Shunt, Transjugular Intrahepatic / Q000009:adverse effects / Q000379:methods*; D055728:Primary Myelofibrosis / Q000150:complications* / Q000473:pathology; D018570:Risk Assessment