title: Antimalarial activity of 1-aryl-3,3-dialkyltriazenes.
abstract: The antimalarial activity of 1-aryl-3,3-dialkyltriazenes to Plasmodium berghei NK-65 in infected mice was evaluated at an intraperitoneal dose of 100mg/kgbw. Some of these compounds were found to possess potent antimalarial activity.
authors.affiliation: Department of Pharmaceutical Sciences, School of Pharmacy, Kinki University, 3-4-1 Kowakae, Higashiosaka, Osaka 577-8502, Japan. k-nishi@phar.kindai.ac.jp
authors.forename: Keiji
authors.initials: K
authors.lastname: Nishiwaki
authors.forename: Azusa
authors.initials: A
authors.lastname: Okamoto
authors.forename: Keizo
authors.initials: K
authors.lastname: Matsuo
authors.forename: Yosuke
authors.initials: Y
authors.lastname: Kawaguchi
authors.forename: Yoshio
authors.initials: Y
authors.lastname: Hayase
authors.forename: Katsuaki
authors.initials: K
authors.lastname: Ohba
mesh_terms: D000818:Animals; D000962:Antimalarials / Q000008:administration & dosage / Q000138:chemical synthesis* / Q000494:pharmacology*; D004912:Erythrocytes / Q000469:parasitology; D005260:Female; D007202:Indicators and Reagents; D007274:Injections, Intraperitoneal; D007279:Injections, Subcutaneous; D009682:Magnetic Resonance Spectroscopy; D008288:Malaria / Q000188:drug therapy* / Q000469:parasitology*; D051379:Mice; D008813:Mice, Inbred ICR; D010962:Plasmodium berghei / Q000187:drug effects*; D021241:Spectrometry, Mass, Electrospray Ionization; D013055:Spectrophotometry, Infrared; D016019:Survival Analysis; D014227:Triazines / Q000008:administration & dosage / Q000138:chemical synthesis* / Q000494:pharmacology*
chemical_list: D000962:Antimalarials; D007202:Indicators and Reagents; D014227:Triazines