Targeting heme-oxidized soluble guanylate cyclase: solution for all cardiorenal problems in heart failure?
Münzel
Thomas
T
Genth-Zotz
Sabine
S
Hink
Ulrich
U
D000818:Animals; D001565:Benzoates / Q000008:administration & dosage / Q000494:pharmacology; D004305:Dose-Response Relationship, Drug; D004789:Enzyme Activation; D006162:Guanylate Cyclase / Q000737:chemistry / Q000378:metabolism*; D006321:Heart / Q000503:physiopathology*; D006333:Heart Failure / Q000378:metabolism / Q000503:physiopathology*; D006418:Heme / Q000378:metabolism*; D006801:Humans; D007668:Kidney / Q000503:physiopathology*; D010084:Oxidation-Reduction; D012995:Solubility
D001565:Benzoates; C480588:BAY 58-2667; D006418:Heme; D006162:Guanylate Cyclase