[The prognostic value of admission blood glucose level in acute myocardial infarction after primary percutaneous coronary intervention].
OBJECTIVE
To evaluate the predictive value of the admission blood glucose level for in-hospital mortality and major adverse cardiac events (MACE) rate in patients with acute myocardial infarction (AMI) who underwent primary percutaneous coronary intervention (PCI).


METHODS
The cohort study comprised 312 consecutive patients with AMI who underwent primary PCI within 24 hours after the onset of chest pain, including diabetic patients and non-diabetic patients. According to the levels of the admission glucose (11 mmol/L), these patients were divided into two groups: a high admission glucose group and a normal admission glucose group.


RESULTS
There were no significant differences in age, hypertension, hyperlipidemia, LVEF, CK-MB and hypersensitive C reactive protein. PCI success rate was similar in both groups (P > 0.05). The in-hospital mortality and 180-day MACE rate were significantly higher in patients with high concentration of admission glucose than in patients with normal concentration (18.2% vs 3.0% P < 0.001, 25% vs 12.7%, P = 0.047). However, there was no significant difference in mortality and 180-day MACE rate between diabetic and non-diabetic patients. Binary logistic regression analysis indicated that high concentration of the admission glucose remained an independent predicator of the in-hospital mortality (OR 5.15, 95% CI 1.74 - 15.28, P = 0.003) and higher occurrence rate of 180-day MACE (OR 2.84, 95% CI 1.18 - 6.83, P = 0.019).


CONCLUSIONS
High concentration of admission glucose, but not the diagnosis of diabetes, was an important predictor for in-hospital mortality and 180-day MACE rate in patients with AMI who underwent primary PCI.
Li
Lei
L
Department of Cardiology, Peking University Third Hospital, Institute of Cardiovascular Research, Beijing 100083, China.
Guo
Yan-hong
YH
Gao
Wei
W
Guo
Li-jun
LJ
D000368:Aged; D015906:Angioplasty, Balloon, Coronary; D001786:Blood Glucose / Q000378:metabolism*; D015331:Cohort Studies; D048909:Diabetes Complications / Q000378:metabolism / Q000401:mortality; D005500:Follow-Up Studies; D017052:Hospital Mortality; D006801:Humans; D006943:Hyperglycemia / Q000150:complications / Q000378:metabolism / Q000401:mortality; D008875:Middle Aged; D009203:Myocardial Infarction / Q000150:complications / Q000378:metabolism* / Q000401:mortality*; D011379:Prognosis; D015996:Survival Rate
D001786:Blood Glucose