title: HIV incidence, retention rate, and baseline predictors of HIV incidence and retention in a prospective cohort study of injection drug users in Xinjiang, China.
abstract: OBJECTIVE
  To determine HIV seroincidence, study participant retention rate, and baseline predictors of HIV incidence and study retention among high-risk injection drug users (IDUs) in Xinjiang, China.
  
  
  METHODS
  A total of 508 eligible seronegative high-risk IDUs were enrolled. Study participants were tested for HIV-1 and counseled at the baseline, 6-month, and 12-month follow-up visits. Sociodemographic and behavioral data were collected during each study visit. The HIV-1 incidence rate and the retention rate were analyzed as a function of sociodemographic, behavioral, and recruitment variables.
  
  
  RESULTS
  At 12 months of follow-up, the HIV-1 incidence rate was 8.8 per 100 person-years (95% CI 6.3-12.0%) and the participant retention rate was 93%. Marital status at baseline was the only predictor of HIV incidence. No baseline variables were predictive of study retention.
  
  
  CONCLUSIONS
  HIV incidence is high among IDUs in Xinjiang, China. Baseline predictors of incidence and retention were minimal. The participant retention rate in this study is promising for the undertaking of future HIV intervention studies.
authors.affiliation: Xinjiang Center for Disease Control and Prevention, Urumqi, China.
authors.forename: Yuanzhi
authors.initials: Y
authors.lastname: Zhang
authors.forename: Hua
authors.initials: H
authors.lastname: Shan
authors.forename: Jennifer
authors.initials: J
authors.lastname: Trizzino
authors.forename: Yuhua
authors.initials: Y
authors.lastname: Ruan
authors.forename: Geetha
authors.initials: G
authors.lastname: Beauchamp
authors.forename: Benoît
authors.initials: B
authors.lastname: Mâsse
authors.forename: Jun
authors.initials: J
authors.lastname: Ma
authors.forename: Baoling
authors.initials: B
authors.lastname: Rui
authors.forename: Jun
authors.initials: J
authors.lastname: Wang
authors.forename: Minsheng
authors.initials: M
authors.lastname: Liu
authors.forename: Yunxia
authors.initials: Y
authors.lastname: Wang
authors.forename: Yixin
authors.initials: Y
authors.lastname: He
authors.forename: Katharine
authors.initials: K
authors.lastname: Poundstone
authors.forename: Yan
authors.initials: Y
authors.lastname: Jiang
authors.forename: J Brooks
authors.initials: JB
authors.lastname: Jackson
authors.forename: Yiming
authors.initials: Y
authors.lastname: Shao
mesh_terms: D000293:Adolescent; D000328:Adult; D002681:China / Q000453:epidemiology; D015331:Cohort Studies; D005260:Female; D015658:HIV Infections / Q000453:epidemiology*; D015497:HIV-1; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D015819:Substance Abuse, Intravenous / Q000453:epidemiology* / Q000821:virology*