Ligand-based drug design methodologies in drug discovery process: an overview.
Ligand-based drug design represents an important research field in the drug discovery and optimisation process. This review provides an overview about the theoretical background of the quantitative structure activity relationship (QSAR) models.
Bacilieri
Magdalena
M
Molecular Modeling Section, Dipartimento di Scienze Farmaceutiche, Università di Padova, Via Marzolo 5, I-35131 Padova, Italy.
Moro
Stefano
S
D015195:Drug Design; D008024:Ligands; D008962:Models, Theoretical; D015394:Molecular Structure; D004364:Pharmaceutical Preparations / Q000737:chemistry* / Q000378:metabolism; D021281:Quantitative Structure-Activity Relationship; D013678:Technology, Pharmaceutical / Q000379:methods
D008024:Ligands; D004364:Pharmaceutical Preparations