title: Hepatotoxicity due to a drug interaction between amodiaquine plus artesunate and efavirenz.
authors.forename: Polina
authors.initials: P
authors.lastname: German
authors.forename: Bryan
authors.initials: B
authors.lastname: Greenhouse
authors.forename: Carrie
authors.initials: C
authors.lastname: Coates
authors.forename: Grant
authors.initials: G
authors.lastname: Dorsey
authors.forename: Philip J
authors.initials: PJ
authors.lastname: Rosenthal
authors.forename: Edwin
authors.initials: E
authors.lastname: Charlebois
authors.forename: Niklas
authors.initials: N
authors.lastname: Lindegardh
authors.forename: Diane
authors.initials: D
authors.lastname: Havlir
authors.forename: Francesca T
authors.initials: FT
authors.lastname: Aweeka
mesh_terms: D000328:Adult; D000480:Alkynes; D000655:Amodiaquine / Q000009:adverse effects* / Q000627:therapeutic use; D037621:Artemisinins / Q000009:adverse effects* / Q000627:therapeutic use; D000077332:Artesunate; D048588:Benzoxazines; D056486:Chemical and Drug Induced Liver Injury; D015331:Cohort Studies; D003521:Cyclopropanes; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D004347:Drug Interactions; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D008107:Liver Diseases / Q000201:enzymology; D008111:Liver Function Tests; D008297:Male; D008875:Middle Aged; D010078:Oxazines / Q000009:adverse effects* / Q000627:therapeutic use; D012016:Reference Values; D018570:Risk Assessment; D012717:Sesquiterpenes / Q000009:adverse effects* / Q000627:therapeutic use; D000637:Transaminases / Q000097:blood
chemical_list: D000480:Alkynes; D037621:Artemisinins; D048588:Benzoxazines; D003521:Cyclopropanes; D010078:Oxazines; D012717:Sesquiterpenes; D000655:Amodiaquine; D000077332:Artesunate; D000637:Transaminases; C098320:efavirenz