Circulating tumour-derived nucleic acids in cancer patients: potential applications as tumour markers.
Tumour-associated changes have been observed in the circulating nucleic acids of cancer patients and have been proposed to be useful for the detection and monitoring of cancers. In this review, different approaches for detecting tumour-associated nucleic acids in the circulation and their potential applications as tumour markers are discussed.
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Department of Chemical Pathology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China.
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D014408:Biomarkers, Tumor / Q000097:blood*; D004273:DNA, Neoplasm / Q000097:blood*; D006801:Humans; D009369:Neoplasms / Q000097:blood* / Q000175:diagnosis* / Q000235:genetics; D009696:Nucleic Acids / Q000097:blood*
D014408:Biomarkers, Tumor; D004273:DNA, Neoplasm; D009696:Nucleic Acids