title: Karyomegalic interstitial nephritis: a pitfall in urine cytology.
abstract: A case of a 44-yr-old Maori female presenting with chronic renal failure due to karyomegalic interstitial nephritis is reported. To our knowledge, this is the first instance this disorder has been reported in a New Zealand Maori. Karyomegalic interstitial nephritis is a rare cause of progressive renal failure, which may be familial, and is frequently associated with a history of recurrent respiratory infections. The urine in this case contained large, pleomorphic cells, mimicking carcinoma. The case therefore illustrates a rare cause of chronic renal failure, and presents an important diagnostic pitfall in the practice of urine cytopathology.
authors.affiliation: Department of Cytology, Wellington Hospital and School of Medicine, Capital and Coast District Health Board, Wellington, New Zealand. david.palmer@ccdhb.org.nz
authors.forename: David
authors.initials: D
authors.lastname: Palmer
authors.forename: Sharda
authors.initials: S
authors.lastname: Lallu
authors.forename: Philip
authors.initials: P
authors.lastname: Matheson
authors.forename: Peter
authors.initials: P
authors.lastname: Bethwaite
authors.forename: Keneth
authors.initials: K
authors.lastname: Tompson
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D007668:Kidney / Q000473:pathology; D009395:Nephritis, Interstitial / Q000473:pathology* / Q000652:urine*