Application of the semi-pinacol rearrangement towards the generation of alkenyl-substituted quaternary carbon centres.
The semi-pinacol rearrangement has been carried out on 2-methyl-2,3-epoxy-cyclopentanone derivatives, generating alkenyl-substituted quaternary carbon centred aldols with a defined relative stereochemistry.
Snape
Timothy J
TJ
Manchester Interdisciplinary Biocentre, University of Manchester, 131 Princess Street, Manchester, Ml 7DN, UK. tim.snape@manchester.ac.uk
D000438:Alcohols / Q000138:chemical synthesis* / Q000737:chemistry; D000475:Alkenes / Q000737:chemistry*; D002244:Carbon / Q000737:chemistry*; D003512:Cyclohexanones / Q000138:chemical synthesis; D003517:Cyclopentanes / Q000138:chemical synthesis / Q000737:chemistry; D003521:Cyclopropanes / Q000138:chemical synthesis; D004852:Epoxy Compounds / Q000737:chemistry; D015394:Molecular Structure; D013237:Stereoisomerism
D000438:Alcohols; D000475:Alkenes; D003512:Cyclohexanones; D003517:Cyclopentanes; D003521:Cyclopropanes; D004852:Epoxy Compounds; D002244:Carbon