Tumor lysis associated with sudden onset of syndrome of inappropriate antidiuretic hormone secretion.
Syndrome of inappropriate antidiuretic hormone secretion is frequent in small-cell lung carcinomas. We report on a case of syndrome of inappropriate antidiuretic hormone secretion after each of the first 2 cycles of chemotherapy for small-cell lung cancer. The association with chemotherapy-induced tumor lysis is proposed, particularly based on the course of antidiuretic hormone levels, and a review of the literature is presented. Syndrome of inappropriate antidiuretic hormone secretion can occur during tumor lysis syndrome.
Saintigny
Pierre
P
Service d'Oncologie Medicale, Hopital Avicenne, Assistance Publique Hpôitaux de Paris, Bobigny, France. pierre.saintigny@avc.ap-hop-paris.fr
Chouahnia
Kader
K
Cohen
Régis
R
Pailler
Marie-Christine
MC
Brechot
Jeanne-Marie
JM
Morere
Jean-François
JF
Breau
Jean-Luc
JL
D018288:Carcinoma, Small Cell / Q000150:complications / Q000188:drug therapy*; D006801:Humans; D007177:Inappropriate ADH Syndrome / Q000209:etiology*; D008175:Lung Neoplasms / Q000150:complications / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D010257:Paraneoplastic Syndromes / Q000209:etiology*; D015275:Tumor Lysis Syndrome / Q000150:complications*; D014667:Vasopressins / Q000097:blood
D014667:Vasopressins