Seven new steroidal glycosides from the roots of Cynanchum forrestii.
Seven new steroidal glycosides, cynaforrosides K (1), L (2), M (3), N (4), and Q (7), based on a 13,14:14,15-disecopregnane-type aglycone, and cynaforrosides O (5) and P (6) with a 14,15-secopregnane-type aglycone, were isolated from the 95% ethanol extract of the roots of Cynanchum forrestii Schlechter. The structures of new compounds were determined on the basis of spectroscopic and chemical evidence. The sugar units of cynaforrosides K-P contained two moieties of glucoses with the mode of 1-->4 linkage and those of cynaforrosides K-O contained six moieties of sugars.
Liu
Yue
Y
Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Peking Union Medical College, Beijing 100050, People's Republic of China.
Qu
Jing
J
Yu
Shi-Shan
SS
Hu
You-Cai
YC
Huang
Xiang-Zhong
XZ
D002240:Carbohydrate Sequence; D031105:Cynanchum / Q000737:chemistry*; D006027:Glycosides / Q000737:chemistry* / Q000302:isolation & purification; D008969:Molecular Sequence Data; D015394:Molecular Structure; D018517:Plant Roots / Q000737:chemistry; D013256:Steroids / Q000737:chemistry* / Q000302:isolation & purification
D006027:Glycosides; D013256:Steroids