Fertility drugs and gynecologic cancer.
Fertility drugs (FD) are spreading worldwide fast and therefore many studies have reviewed the possible association between the use of these drugs and cancer. Since the drugs used for ovulation induction during in vitro fertilization (IVF) like hCG, hMG, rFSH increase the levels of gonadal hormones, concerns have grown regarding the risk of developing cancer in breast, ovary, endometrium, and other target organs. In this review, we discuss a number of different studies published in recent years that show no association between the use of these drugs and most cancers.
Kanakas
Nikos
N
In Vitro Fertilization Unit, Euromedica, Athens, Greece. nkanakas@hol.gr
Mantzavinos
Themis
T
D019317:Evidence-Based Medicine; D005260:Female; D005300:Fertility Agents, Female / Q000008:administration & dosage / Q000009:adverse effects; D005833:Genital Neoplasms, Female / Q000139:chemically induced; D006801:Humans; D010062:Ovulation Induction / Q000009:adverse effects*
D005300:Fertility Agents, Female