title: Zollinger Ellison syndrome, treated with lansoprazole, during pregnancy.
abstract: BACKGROUND
  Zollinger Ellison syndrome (ZES), an ulcerative disease of the upper gastrointestinal tract that involves the production of high levels of gastrin and gastric acid, is a rare, symptomatic, endocrine neoplastic disease.
  
  
  METHODS
  We report a rare case of gastrinoma that was first diagnosed during pregnancy in which the primary tumor was located in the liver. The ZES was well controlled with Zoton (Lansoprazole) following surgery. The patient had an uneventful pregnancy and delivery without significant complications.
  
  
  CONCLUSIONS
  The present case suggests that treatment with Zoton for ZES during pregnancy is safe and effective.
authors.affiliation: Department of Obstetrics and Gynecology, Faculty of Health Sciences, Soroka University Medical Center, Ben Gurion University of the Negev, P.O. Box 151, Beer-Sheva 84101, Israel. amayer@bgumail.bgu.ac.il
authors.forename: Amit
authors.initials: A
authors.lastname: Mayer
authors.forename: Eyal
authors.initials: E
authors.lastname: Sheiner
authors.forename: Gershon
authors.initials: G
authors.lastname: Holcberg
mesh_terms: D053799:2-Pyridinylmethylsulfinylbenzimidazoles / Q000627:therapeutic use*; D000328:Adult; D000897:Anti-Ulcer Agents / Q000627:therapeutic use*; D005260:Female; D015408:Gastrinoma / Q000150:complications* / Q000188:drug therapy / Q000473:pathology / Q000601:surgery; D005755:Gastrins / Q000097:blood; D006801:Humans; D007231:Infant, Newborn; D064747:Lansoprazole; D008297:Male; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000097:blood / Q000188:drug therapy* / Q000601:surgery; D011256:Pregnancy Outcome; D015043:Zollinger-Ellison Syndrome / Q000097:blood / Q000150:complications / Q000188:drug therapy* / Q000601:surgery
chemical_list: D053799:2-Pyridinylmethylsulfinylbenzimidazoles; D000897:Anti-Ulcer Agents; D005755:Gastrins; D064747:Lansoprazole