title: Successful treatment of mandibular squamous cell carcinoma in a Malayan sun bear (Helarctos malayanus).
abstract: An adult, female Malayan sun bear (Helarctos malayanus) was diagnosed with squamous cell carcinoma of the rostral mandible. Initial treatment included bilateral mandibulectomy rostral to the lingual frenulum followed by intra- and perilesional cisplatin injections. Recovery after the procedure was uneventful and the Malayan sun bear adapted well to a shortened mandible. Histopathology indicated incomplete surgical excision of the tumor; therefore, radiation therapy was instituted weekly for four treatments at 2 Gy in parallel opposed fields (total 4 Gy each treatment) with one additional cisplatin treatment. Two years after initial presentation, the animal showed no recurrence of neoplasia.
authors.affiliation: Lincoln Park Zoo, 2001 North Clark Street, Chicago, Illinois 60614, USA.
authors.forename: Natalie D
authors.initials: ND
authors.lastname: Mylniczenko
authors.forename: Ann L
authors.initials: AL
authors.lastname: Manharth
authors.forename: Leigh Ann
authors.initials: LA
authors.lastname: Clayton
authors.forename: Rhonda
authors.initials: R
authors.lastname: Feinmehl
authors.forename: Mitch
authors.initials: M
authors.lastname: Robbins
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D002294:Carcinoma, Squamous Cell / Q000188:drug therapy / Q000601:surgery / Q000662:veterinary*; D002945:Cisplatin / Q000627:therapeutic use*; D005260:Female; D008296:Malaysia; D008339:Mandibular Neoplasms / Q000188:drug therapy / Q000601:surgery / Q000662:veterinary*; D016896:Treatment Outcome; D001503:Ursidae
chemical_list: D000970:Antineoplastic Agents; D002945:Cisplatin