Poly A and symmetrical transcription of SV40 DNA.
A scheme is proposed for the maturation of SV40 message late in the infection of monkey cells: precursor viral RNA molecules are transcribed symmetrically after which poly A is added to both self-complementary transcripts. Certain sequences are then degraded to yield poly A-containing, non-complementary mature message.
Aloni
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Y
Department of Genetics, The Weizmann Institute of Science, Rehovot, Israel.
D000818:Animals; D002460:Cell Line; D002850:Chromatography, Gel; D015342:DNA Probes / Q000235:genetics; D004279:DNA, Viral / Q000235:genetics*; D005374:Filtration; D015967:Gene Expression Regulation, Viral; D000882:Haplorhini; D011061:Poly A / Q000235:genetics*; D012313:RNA / Q000138:chemical synthesis / Q000737:chemistry / Q000235:genetics / Q000378:metabolism; D012260:Ribonucleases / Q000378:metabolism; D013539:Simian virus 40 / Q000235:genetics*; D014158:Transcription, Genetic / Q000235:genetics*
D015342:DNA Probes; D004279:DNA, Viral; D011061:Poly A; D012313:RNA; D012260:Ribonucleases