[Correlation of erythrocyte immune function between normal neonates and their mothers].
OBJECTIVE
To study the correlation of erythrocyte immune function between normal neonates and their mothers and the influence of various obstetric factors on neonatal erythrocyte immune function.


METHODS
The adherent rate of complement 3b-receptor on the surface of red blood cells (RBC-C3bRR) and the immune complex adherent rate of red blood cells (RBC-ICR) were detected using the erythrocyte saccharomyces rosette test in 104 normal neonates and their mothers. The correlation of erythrocyte immune function between neonates and their mothers was evaluated by the maternal-infant paired test.


RESULTS
The levels of RBC-C3bRR (16.80 +/- 1.56% vs 16.23 +/- 1.63%; P < 0.05) and RBC-ICR (5.72 +/- 1.63% vs 5.02 +/- 1.38%; P < 0.01) in neonates were significantly higher than those in their mothers. There was a significantly positive correlation in RBC-ICR levels between neonates and their mothers (r = 0.28, P < 0.05). No correlation was found in RBC-C3bRR levels between the two groups. Neither RBC-C3bRR nor RBC-ICR levels of neonates were associated with various obstetric factors such as amniotic fluid, placenta, umbilical cord, parturient patterns, and puerperal anemia and pregnancy-induced hypertension syndrome.


CONCLUSIONS
The erythrocyte immune function in neonates has a relatively mature level and correlates with their mothers' erythrocyte immune function. Various obstetric factors have no influences on neonatal erythrocyte immune function.
Lin
Li-Xing
LX
Department of Pediatrics, First Hospital of Lanzhou University, Lanzhou 730000, China.
Zhang
Xiao-Yan
XY
He
Xiao-Qin
XQ
Tao
Zhong-Bin
ZB
D000936:Antigen-Antibody Complex / Q000276:immunology; D004912:Erythrocytes / Q000276:immunology*; D005260:Female; D005312:Fetal Blood / Q000276:immunology*; D006801:Humans; D007231:Infant, Newborn / Q000276:immunology*; D016014:Linear Models; D008297:Male; D011247:Pregnancy; D017463:Receptors, Complement 3b / Q000032:analysis; D012397:Rosette Formation
D000936:Antigen-Antibody Complex; D017463:Receptors, Complement 3b