title: Functional assessment of chronic illness therapy-fatigue scale is valid in patients with psoriatic arthritis.
abstract: BACKGROUND
  Fatigue is an important symptom in psoriatic arthritis (PsA).
  
  
  OBJECTIVE
  To determine the reliability and validity of the Functional Assessment of Chronic Illness Therapy-Fatigue (FACIT fatigue) Scale in PsA.
  
  
  METHODS
  Consecutive patients attending the PsA clinic were assessed with the FACIT fatigue Scale twice, 1 week apart. Patients were assessed clinically according to a standardised PsA clinic protocol. Internal consistency of the 13 items on the FACIT fatigue questionnaire was measured using Cronbach's alpha; test-retest reliability by the intraclass correlation coefficient (ICC), and validity by the correlation of the FACIT fatigue results with other fatigue measures and disease characteristics.
  
  
  RESULTS
  135 patients (80 men and 55 women, mean (SD) age 52 (13) years, mean (SD) disease duration 17 (10) years) participated. The mean FACIT fatigue score was 35.8 (12.4). Cronbach's alpha was 0.96. Repeat questionnaires were returned by 54% of patients. No difference in disease characteristics was observed between those who did and did not return the questionnaires. The ICC for first and repeat FACIT fatigue scores was 0.95. The correlation between the FACIT fatigue and modified Fatigue Severity Score was -0.79 (95% CI -0.85 to -0.72). FACIT fatigue scores were lower in patients with overwhelming fatigue and fibromyalgia than in those without (p<0.001). The FACIT fatigue was correlated with the actively inflamed joint count (-0.43, 95% CI -0.56 to -0.28, p<0.001), but not with the clinically damaged joint count (-0.06, 95% CI -0.23 to 0.11, p = 0.51).
  
  
  CONCLUSIONS
  The FACIT fatigue results were reproducible, and correlated with other fatigue measures as well as with disease activity in patients with PsA. Therefore, the FACIT fatigue is a reliable and valid instrument to measure fatigue in PsA.
authors.affiliation: Psoriatic Arthritis Program, University Health Network, Toronto Western Hospital, 399 Bathurst Street, 1E-410B, Toronto, Ontario, Canada M5T 2S8.
authors.forename: Vinod
authors.initials: V
authors.lastname: Chandran
authors.forename: Sita
authors.initials: S
authors.lastname: Bhella
authors.forename: Catherine
authors.initials: C
authors.lastname: Schentag
authors.forename: Dafna D
authors.initials: DD
authors.lastname: Gladman
mesh_terms: D000367:Age Factors; D015535:Arthritis, Psoriatic / Q000150:complications* / Q000473:pathology; D002908:Chronic Disease; D005221:Fatigue / Q000150:complications / Q000175:diagnosis*; D005260:Female; D006801:Humans; D007596:Joints / Q000473:pathology; D008297:Male; D008875:Middle Aged; D015203:Reproducibility of Results; D012720:Severity of Illness Index; D012737:Sex Factors; D011795:Surveys and Questionnaires