title: [Mood and emotional disorders in Multiple Sclerosis: a literature review].
abstract: BACKGROUND
  Even though mood and emotion are closely related concepts, they differ in some ways. This article aims to review the main mood and emotional disorders most often found in Multiple Sclerosis (MS).
  
  
  BACKGROUND
  Studies related to four fields are presented and discussed: assessment tools and methodological problems; prevalence, etiology and symptoms of mood as well as emotional disorders in MS; relationship between cognition and emotion. Beside these main subjects, we tackle some interesting questions which concern patients as well as clinicians, such as the risk of depression and protective factors, the relationship between depression and fatigue and the impact of beta-interferon on depression.
  
  
  CONCLUSIONS
  We focus on a new promising trend aiming to link neuroimaging data to psychological variables.
  
  
  CONCLUSIONS
  These four fields cover a large portion of the questions about mood and emotional disorders in MS. Due to their frequency as well as to their impact on quality of life, specific attention should be given to these disorders.
authors.affiliation: Laboratoire de Psychopathologie et Neuropsychologie Cliniques, Université Paris Descartes et Centre d'Investigation Clinique de l'Hôpital La Pitié-Salpêtrière. montel.s@wanadoo.fr
authors.forename: S
authors.initials: S
authors.lastname: Montel
authors.forename: C
authors.initials: C
authors.lastname: Bungener
mesh_terms: D000342:Affective Symptoms / Q000209:etiology*; D003072:Cognition Disorders / Q000209:etiology; D003863:Depression / Q000209:etiology; D006801:Humans; D019964:Mood Disorders / Q000209:etiology*; D009103:Multiple Sclerosis / Q000150:complications* / Q000523:psychology*; D013405:Suicide