title: [An epilepsy case presenting temporal aphonia and prosodic deficit with left hemiparesis].
abstract: A 53-year-old right-handed woman was admitted to a hospital with a seizure, exhibiting loss of consciousness and paroxysmal myoclonic movement. MRI showed no abnormalities of her brain. Electroencephalography revealed sporadic sharp and slow wave complexes, starting from the right central region. Cerebral perfusion SPECT revealed increased blood supply in the right hemisphere. She received diagnosis of epilepsy and was treated with phenytoin. After she regained her consciousness, she had no voice and presented with left hemiparesis which was interpreted to be Todd's palsy. She gradually recovered in using her voice, to full normalization of affective prosody in 11 days. The left hemiparesis recovered first in the upper and later in the lower extremities. Her symptoms could be interpreted to be vocal and prosodic disturbance, but not aphasia, because she could understand speach and communicate with writing. The lesions responsible for prosodic deficit are still controversial. The symptoms observed and the findings obtained may indicate that the deficiency of the affective prosody may be caused by the dysfunction of the medial surface of the non-dominant frontal lobe in this case.
authors.affiliation: Department of Neurology, Research Institute for Brain and Blood Vessels, Akita.
authors.forename: Taizen
authors.initials: T
authors.lastname: Nakase
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Maeda
authors.forename: Akifumi
authors.initials: A
authors.lastname: Suzuki
authors.forename: Ken
authors.initials: K
authors.lastname: Nagata
mesh_terms: D001044:Aphonia / Q000209:etiology*; D001921:Brain / Q000098:blood supply / Q000473:pathology; D004292:Dominance, Cerebral; D004569:Electroencephalography; D004827:Epilepsy / Q000209:etiology*; D005260:Female; D005625:Frontal Lobe / Q000503:physiopathology; D006429:Hemiplegia / Q000150:complications*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D013064:Speech Disorders / Q000209:etiology*