title: Reversible endotension associated with excessive warfarin anticoagulation.
abstract: An aortic aneurysm was successfully treated with an endovascular stent graft, with no evidence of endoleak and documented progressive aortic diameter reduction during the first 23 months. At 29 months, the patient had documented enlargement of the aneurysm sac associated with excessive anticoagulation with warfarin. No evidence of endoleak could be demonstrated with any diagnostic modality. Progressive aneurysm sac diameter regression was documented after reversal of excessive anticoagulation to therapeutic levels (international normalized ratio of 2 to 3). Strict monitoring of coagulation profile in patients after endovascular aneurysm repair requiring anticoagulation with warfarin is recommended to avoid this complication, which to our knowledge has not been previously reported.
authors.affiliation: Division of Vascular Surgery, McGill University, Montréal, Québec, Canada.
authors.forename: Vikram S
authors.initials: VS
authors.lastname: Iyer
authors.forename: Kent S
authors.initials: KS
authors.lastname: Mackenzie
authors.forename: Marc-Michel
authors.initials: MM
authors.lastname: Corriveau
authors.forename: Oren K
authors.initials: OK
authors.lastname: Steinmetz
mesh_terms: D000368:Aged; D000925:Anticoagulants / Q000009:adverse effects*; D017544:Aortic Aneurysm, Abdominal / Q000097:blood / Q000473:pathology* / Q000601:surgery; D001027:Aortography; D001777:Blood Coagulation / Q000187:drug effects; D019917:Blood Vessel Prosthesis Implantation; D006801:Humans; D019934:International Normalized Ratio; D008297:Male; D015607:Stents; D013997:Time Factors; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D014859:Warfarin / Q000009:adverse effects*
chemical_list: D000925:Anticoagulants; D014859:Warfarin