Novel human rotavirus of genotype G5P[6] identified in a stool specimen from a Chinese girl with diarrhea.
During a rotavirus surveillance conducted in Lulong County, Hebei Province, China, a total of 331 stool specimens collected in 2003 from children under 5 years old with diarrhea were screened. We identified a novel group A human rotavirus of genotype G5P[6]. Phylogenetic analysis confirmed that the VP7 protein of this newly identified strain, LL36755, was closely related to those of the G5 strains. As such, it has 95.4% homology with its counterparts in the porcine G5 strains C134 and CC117 at the amino acid sequence level. On the other hand, the VP4 protein of the LL36755 strain was 94.5% homologous to those of the porcine P[6] strains 134/04-10, 134/04-11, 221/04-7, and 221/04-13. Our findings indicate a dynamic interaction between human and porcine rotaviruses.
Duan
Zhao-Jun
ZJ
National Institute for Viral Disease Control and Prevention, Beijing, China. zhaojund@126.com
Li
Dan-Di
DD
Zhang
Qing
Q
Liu
Na
N
Huang
Can-Ping
CP
Jiang
Xi
X
Jiang
Baomin
B
Glass
Roger
R
Steele
Duncan
D
Tang
Jing-Yu
JY
Wang
Zhong-Shan
ZS
Fang
Zhao-Yin
ZY
D002681:China; D003967:Diarrhea / Q000821:virology*; D005243:Feces / Q000821:virology*; D005260:Female; D005814:Genes, Viral; D005838:Genotype; D006801:Humans; D007223:Infant; D008969:Molecular Sequence Data; D010802:Phylogeny; D011159:Population Surveillance; D012401:Rotavirus / Q000235:genetics* / Q000302:isolation & purification*