title: Mortality following liver resection in US medicare patients: does the presence of a liver transplant program affect outcome?
abstract: BACKGROUND
  Hepatic resection is a complicated procedure, at times associated with significant morbidity. Liver transplantation programs may improve outcomes following resective liver surgery at the institutional level by a number of means, including: availability of ancillary services and personnel, specialized critical care, and added surgical expertise.
  
  
  OBJECTIVE
  To determine if the presence of a liver transplant program at a center improves outcomes following hepatic resection when compared to centers without an associated liver transplant program.
  
  
  METHODS
  Using data from the national Medicare claims database, 30-day mortality following all hepatic resections performed over a 2-year period (1999, 2000) were studied. Regression techniques were used to assess the relationship between mortality at centers with an associated liver transplant program in comparison to those without, while controlling for potential confounding factors.
  
  
  RESULTS
  The proportion of patients dying within 30 days among 4,661 patients that underwent hepatic resection was 6.65%. Factors that did increase the risk of dying after hepatic resection included: urgent or emergent surgery (vs. elective), primary liver cancer (vs. metastatic), male sex, increasing comorbidity score, low hospital volume, and extent of surgery. The presence of a liver transplant program within a center was not associated with any improvement in mortality.
  
  
  CONCLUSIONS
  At an institutional level, the presence of a liver transplant program was not associated with decreased 30-day mortality following hepatic resection.
authors.affiliation: Harvard School of Public Health, Boston, Massachusetts, USA. elijah.dixon@calgaryhealthregion.ca
authors.forename: Elijah
authors.initials: E
authors.lastname: Dixon
authors.forename: Sebastian
authors.initials: S
authors.lastname: Schneeweiss
authors.forename: Janice L
authors.initials: JL
authors.lastname: Pasieka
authors.forename: Oliver F
authors.initials: OF
authors.lastname: Bathe
authors.forename: Francis
authors.initials: F
authors.lastname: Sutherland
authors.forename: Christopher
authors.initials: C
authors.lastname: Doig
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D015897:Comorbidity; D019992:Databases as Topic; D004630:Emergencies; D005260:Female; D017052:Hospital Mortality; D006761:Hospitals / Q000706:statistics & numerical data; D006801:Humans; D007902:Length of Stay; D016014:Linear Models; D008099:Liver / Q000601:surgery*; D008113:Liver Neoplasms / Q000401:mortality / Q000601:surgery; D016031:Liver Transplantation / Q000706:statistics & numerical data*; D008297:Male; D006278:Medicare; D012737:Sex Factors; D014481:United States