title: Estimating choroidal melanoma volume: comparison of methods.
abstract: OBJECTIVE
  To evaluate published methods of estimating choroidal melanoma volume.
  
  
  METHODS
  Prospective consecutive case series.
  
  
  METHODS
  Ten consecutive patients with primary choroidal melanoma.
  
  
  METHODS
  After determination of tumor dimensions (largest tumor basal diameter, basal perpendicular diameter, and height), tumor volume was calculated for each tumor by using the 5 published methods. Percent differences in tumor volume were determined for each tumor as calculated by different methods.
  
  
  METHODS
  Choroidal melanoma volume.
  
  
  RESULTS
  The mean variation in estimated tumor volume expressed as a ratio was 2.33 (range, 1.64-3.84).
  
  
  CONCLUSIONS
  Choroidal melanoma volume calculation methods are inconsistent and caution is needed when volume measures are used for prognostic classification.
authors.affiliation: Department of Ophthalmic Oncology, Cole Eye Institute, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA. singha@ccf.org
authors.forename: Arun D
authors.initials: AD
authors.lastname: Singh
authors.forename: Sam
authors.initials: S
authors.lastname: Terman
authors.forename: LuAnne
authors.initials: L
authors.lastname: Sculley
mesh_terms: D002830:Choroid Neoplasms / Q000473:pathology*; D003941:Diagnostic Techniques, Ophthalmological; D006801:Humans; D008545:Melanoma / Q000473:pathology*; D008962:Models, Theoretical; D011446:Prospective Studies