title: [Effect of preparation on the major chemical constituents of Polygonum multiflorum].
abstract: OBJECTIVE
  To study the dynamic changes of Emodin, Physcion, Emodin-8-O-beta-D-glucopyranoside, Physcion-8-O-beta-D-glucopyranoside and 2,3,5,4'-tetrahydtoxysilbene-2-O-beta-D-glucopyranoside in Polygonum multiflorum during preparation and analyze their changing laws.
  
  
  METHODS
  Five major constituents before and after preparation were determined by RP-HPLC methods.
  
  
  RESULTS
  The five ingredients decreased significantly after preparation.
  
  
  CONCLUSIONS
  The major chemical constituents of Polygonum multiflorum decrease significantly, suggesting the necessarity of prepared Polygonum multiflorum in clinical application worth studying.
authors.affiliation: Department of Pharmacy, The 88th Hospital of PLA, Tai' an 271000, China.
authors.forename: Zhi-guo
authors.initials: ZG
authors.lastname: Zhang
authors.forename: Tai-sheng
authors.initials: TS
authors.lastname: Lü
authors.forename: Qing-qiang
authors.initials: QQ
authors.lastname: Yao
mesh_terms: D000880:Anthraquinones / Q000032:analysis* / Q000302:isolation & purification; D002851:Chromatography, High Pressure Liquid / Q000379:methods; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification; D004642:Emodin / Q000031:analogs & derivatives* / Q000032:analysis* / Q000302:isolation & purification; D000431:Ethanol; D005960:Glucosides / Q000032:analysis / Q000302:isolation & purification; D006358:Hot Temperature; D035281:Plant Tubers / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry; D028502:Polygonum / Q000737:chemistry*; D013267:Stilbenes / Q000032:analysis / Q000302:isolation & purification; D013678:Technology, Pharmaceutical / Q000379:methods*; D013997:Time Factors
chemical_list: D000880:Anthraquinones; D004365:Drugs, Chinese Herbal; D005960:Glucosides; D013267:Stilbenes; D000431:Ethanol; D004642:Emodin