title: Moderate exercise-induced energy expenditure does not alter leptin levels in sedentary obese men.
abstract: OBJECTIVE
  The purpose of the study was to determine whether exercise-induced increases in energy expenditure (EE) alter circulating leptin levels in obese individuals.
  
  
  METHODS
  Participants were randomized to an exercise intervention group (n = 8) or nonexercising control (n = 7).
  
  
  METHODS
  All data were collected on an outpatient basis at the exercise physiology laboratory at the University of Central Florida.
  
  
  METHODS
  Fifteen healthy obese males (24.9 +/- 1.4 years old, body mass index 33.4 +/- 0.7 kg . m).
  
  
  METHODS
  Members of the intervention group underwent a single exercise session of moderate intensity (58.4 +/- 1.3% of VO2max) for 60 minutes.
  
  
  METHODS
  Postexercise, 24 hour postexercise, and 48 hour postexercise levels of leptin, insulin, and ghrelin.
  
  
  RESULTS
  The exercise session elicited an EE of 567 +/- 25 Kcal. No significant main effect or time-by-group interactions for leptin or ghrelin were observed immediately after the exercise bout or in the days following the intervention.
  
  
  CONCLUSIONS
  These preliminary data suggest that a bout of acute exercise of moderate intensity and duration does not affect leptin concentration. It is possible that a higher level of EE is required to elicit substantial changes.
authors.affiliation: Center for Lifestyle Medicine and Department of Health Professions, University of Central Florida, 12201 Research Parkway, Orlando, FL 32826, USA.
authors.forename: George A
authors.initials: GA
authors.lastname: Kyriazis
authors.forename: Jonathan D
authors.initials: JD
authors.lastname: Caplan
authors.forename: Joshua
authors.initials: J
authors.lastname: Lowndes
authors.forename: Richard L
authors.initials: RL
authors.lastname: Carpenter
authors.forename: Karen E
authors.initials: KE
authors.lastname: Dennis
authors.forename: Stephen A
authors.initials: SA
authors.lastname: Sivo
authors.forename: Theodore J
authors.initials: TJ
authors.lastname: Angelopoulos
mesh_terms: D000328:Adult; D004734:Energy Metabolism; D015444:Exercise / Q000502:physiology*; D054439:Ghrelin; D006801:Humans; D020738:Leptin / Q000097:blood / Q000502:physiology*; D008297:Male; D009043:Motor Activity / Q000502:physiology*; D009765:Obesity / Q000503:physiopathology*; D036361:Peptide Hormones / Q000097:blood; D011446:Prospective Studies; D012737:Sex Factors; D011795:Surveys and Questionnaires; D013997:Time Factors
chemical_list: D054439:Ghrelin; D020738:Leptin; D036361:Peptide Hormones