title: [Clinical effect of Prunellae Oral Liquid on goiter with different thyroid function].
abstract: OBJECTIVE
  To observe the clinical effects of Prunellae Oral Liquid (POL) on the size of thyroid with different states of thyroid function in patients of goiter.
  
  
  METHODS
  Fifty-six patients with hyperthyroidism, 24 with hypothyroidism and 18 with simple goiter were randomized into two groups. Group A treated by classical therapy, Group B by POL based on classical therapy. Size of thyroid of patients before and after treatment was measured by color ultrasonic Doppler and compared with the data obtained from 20 healthy subjects as control.
  
  
  RESULTS
  Size of thyroid in all patients before treatment were obviously larger than that of normal control (P<0.01), but it reduced after treatment in both groups, especially in group B, in which it differed insignificantly to that in the normal control (P > 0.05).
  
  
  CONCLUSIONS
  Combined treatment of Chinese medicine (using POL) and Western medicine is superior to Western medicine alone in treating goiter with different states of thyroid function.
authors.affiliation: Department of Endocrinology, Dongfeng Hospital Affiliated to Yunyang Medical College, Hubei. yangkun@medmail.com.cn
authors.forename: Kun
authors.initials: K
authors.lastname: Yang
authors.forename: Kun-quan
authors.initials: KQ
authors.lastname: Guo
authors.forename: Hai-yan
authors.initials: HY
authors.lastname: Wu
mesh_terms: D000328:Adult; D013956:Antithyroid Agents / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use; D005260:Female; D006042:Goiter / Q000188:drug therapy* / Q000503:physiopathology; D006801:Humans; D006980:Hyperthyroidism / Q000188:drug therapy* / Q000503:physiopathology; D007037:Hypothyroidism / Q000188:drug therapy* / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D008517:Phytotherapy; D010936:Plant Extracts / Q000627:therapeutic use; D031347:Prunella / Q000737:chemistry*; D013961:Thyroid Gland / Q000187:drug effects / Q000503:physiopathology; D016896:Treatment Outcome
chemical_list: D013956:Antithyroid Agents; D004365:Drugs, Chinese Herbal; D010936:Plant Extracts