[Histological evaluation of ischemic injury to the spinal cord. Experimental study in the rabbit].
Sometimes in clinical practice the spinal cord is subjected to a more or less prolonged period of ischemia, after which cellular lesions may occur, causing paraplegia. The purpose of this paper is to quantify morphologically the damage of the spinal cord after an induced ischemia. Seventy male adult rabbits were used. They were divided into three groups: one group was used for evaluation of spinal cord ischemia at 3 hours, the second at 12 hours and the third at 24 hours. The recovery periods ranged from 3, to 12 and 24 hours. At the end of this period, the animals were anesthetized and killed. A clinical evaluation was made using the Tarlov method and criteria. The spinal cord was subjected to a histological evaluation. The results revealed different changes according to the multiple groups of study. The authors discuss the data of the present study and compare to the reports published in the bibliography on the subject.
Vaquero
Carlos
C
Laboratorio de Investigación Quirúrgica, Hospital Clínico Universitario, Universidad de Valladolid, Santa Cruz de Tenerife, Canarias.
Arce
Nuria
N
Agudo
Javier
J
Martinez
Rafael
R
Gutiérrez
Vicente
V
Diago
Maria Victoria
MV
D000818:Animals; D011817:Rabbits; D020760:Spinal Cord Ischemia / Q000473:pathology*