[Circulating endothelial cells--markers of blood vessel lesions in patients with diffuse liver disease].
The increased level of the circulating endothelial cells (CEC) is in direct dependance with a degree of an endothelial trauma. We defined CEC in blood (cells x 104/L) of 67 adults and children with acute and chronic viral hepatitis (A and B) and healthy volontiars. The author obtained reliable results of increased CEC in all groups consisting of patients with diffuse liver deseases (17,4+/-6,5 and 19,8+/-8,4) in comparison with control groups (3,8+/-1,9 and 3,8+/-1,2) thus CEC can be of practical value as a marker of microvessel lesions of the liver. Endotheliocytemia testifies to be a factor during endothelial trauma in pathogenesis of diffuse liver disease.
Dynnik
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OB
D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D015415:Biomarkers / Q000097:blood; D002452:Cell Count; D002648:Child; D042783:Endothelial Cells / Q000166:cytology*; D005260:Female; D006506:Hepatitis A / Q000097:blood / Q000150:complications* / Q000000981:diagnostic imaging; D006509:Hepatitis B / Q000097:blood / Q000150:complications* / Q000000981:diagnostic imaging; D019694:Hepatitis B, Chronic / Q000097:blood / Q000150:complications / Q000000981:diagnostic imaging; D006801:Humans; D008111:Liver Function Tests; D008297:Male; D016491:Peripheral Vascular Diseases / Q000097:blood / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000209:etiology / Q000503:physiopathology; D013152:Splanchnic Circulation; D018616:Ultrasonography, Doppler, Duplex
D015415:Biomarkers