Chitohexose induce the yeast proliferation of Candida albicans.
Candida albicans generally grows in the hyphae form in RPMI1640 medium. Chitohexose (COS-6) induced the yeast form of C. albicans dose-dependently under this condition. When COS-6 was exposed to C. albicans, yeast proliferation was observed 6 h after starting the incubation. When we observed the growth form of C. albicans cultured with COS-6, yeast proliferation was observed at log-phase. These results showed that COS-6 was useful for the yeast form inducer of C. albicans.
Kadowaki
Osamu
O
Department of Microbiology, Tohoku Pharmaceutical University, 4-4-1, Komatsushima, Aoba-ku, Sendai 981-8558, Japan.
Ogasawara
Ayako
A
Watanabe
Toshihiko
T
Mikami
Takeshi
T
Matsumoto
Tatsuji
T
Misawa
Yoshitomo
Y
Matahira
Yoshiharu
Y
Sakai
Kazuo
K
D002176:Candida albicans / Q000166:cytology / Q000187:drug effects* / Q000254:growth & development; D002455:Cell Division / Q000187:drug effects; D015169:Colony Count, Microbial / Q000379:methods; D004305:Dose-Response Relationship, Drug; D009844:Oligosaccharides / Q000494:pharmacology*; D013997:Time Factors
D009844:Oligosaccharides; C050523:chitohexaose