[Constitutive characteristics and change trend of gynecological malignant tumors in 8009 hospitalized patients in Guangxi Zhuang Autonomous Region].
OBJECTIVE
To investigate the constitutive characteristics and the change trend of gynecologic malignant tumors in hospitalized patients in Guangxi Zhuang Autonomous Region over the recent 20 years.


METHODS
Clinical data of 8009 in-patients who suffered from gynecologic malignant tumors in 23 hospitals from 1985 to 2004 in Guangxi Zhuang Autonomous Region were analyzed, with respect to the tumor types and change trend.


RESULTS
(1) The leading 4 types of malignant tumors were cervical cancers, ovarian cancers, endometrial cancers, and malignant trophoblastic tumors according to the constitutive ratios of the tumors. The constitutive ratio of cervical cancer patients rose year by year, from 17.48% during the 1985-1989 period to 49.25% during the 2000-2004 period (P < 0.01). While the constitutive ratio of malignant trophoblastic tumors dropped year by year. The changes of ovarian cancer, endometrial cancer, vulvar and vaginal carcinomas, and sarcoma of the uterus were not obvious (P > 0.05). (2) The occurring age of cervical cancers became younger obviously, from > or = 60 years old dropped to < 40 years old. (3) Cervical cancers were found mainly in urban residents in the former 10 years, the constitutive ratio being 67.1%; while in the latter 10 years it gradually shifted to rural residents, accounting for 52.6% of the total gynecological tumors. (4) Patients were usually at stages II, III, IV when they visited a doctor for their diseases. Especially for ovarian cancer, malignant trophoblastic tumors, sarcoma of the uterus, these patients were in the intermediate or advanced stage when they were diagnosed, mainly because of lack of obvious symptoms. The constitutive ratio of these advanced patients was over 60%.


CONCLUSIONS
We should strengthen the screening program of cervical cancer, and pay more attention to prevention and control of other gynecological reproductive organ tumors at the same time. On the other hand, we should explore better tumor markers, new methods of diagnosis and treatment to improve early diagnosis and treatment of gynecologic malignant tumors.
Huang
Wei
W
Department of Gynecologic Oncology, Affiliated Cancer Hospital of Medical University of Guangxi, Nanning, China.
Li
Li
L
Yu
Dong-qing
DQ
Huang
Ying-lan
YL
Liu
Yan
Y
Chen
Xin-qiu
XQ
Tang
Bu-jian
BJ
Xu
Hong
H
Ma
Gang
G
Dong
Lin-hong
LH
Li
Lian
L
Qiu
Ying
Y
Bai
Hua
H
Nong
Wen-zheng
WZ
Li
Li
L
Zeng
Ding-yuan
DY
Jiang
Fu-yan
FY
Lan
Ying
Y
Ye
Yuan
Y
Tang
Xiong-zhi
XZ
Wang
Dan-xia
DX
Li
Hui-zhen
HZ
Pan
Yan-bo
YB
Mo
Ai-xu
AX
Wu
Xiao-yan
XY
Lei
Zhi-ying
ZY
Zhou
Guo-ping
GP
Liu
Cui
C
Su
Qing-hong
QH
D000328:Adult; D000367:Age Factors; D002681:China / Q000453:epidemiology; D016889:Endometrial Neoplasms / Q000453:epidemiology / Q000473:pathology; D005260:Female; D005833:Genital Neoplasms, Female / Q000453:epidemiology* / Q000473:pathology; D006801:Humans; D008875:Middle Aged; D009367:Neoplasm Staging; D010051:Ovarian Neoplasms / Q000453:epidemiology / Q000473:pathology; D012189:Retrospective Studies; D013997:Time Factors; D002583:Uterine Cervical Neoplasms / Q000453:epidemiology / Q000473:pathology; D014846:Vulvar Neoplasms / Q000453:epidemiology / Q000473:pathology