title: Valvular strands and ischemic stroke.
abstract: We report the case of a previously healthy 47-year-old woman suffering an acute embolic stroke in the left middle cerebral artery distribution. A filiform structure along the line of the aortic valve was first identified by transesophageal echocardiography, leading to the diagnosis of a valvular strand. These masses are thought to represent giant Lambl's excrescences, although differential diagnoses include several benign cardiac tumors, e.g. papillary fibroelastoma. Valvular strands have previously been associated with embolic events including stroke, although exact pathogenetic mechanisms and further patient management have not yet been fully established. This case report additionally provides a short overview of the currently existing literature. As a conclusion, standard recommendations for patient management and treatment cannot be derived from currently available evidence.
authors.affiliation: Department of Neurology, University of Ulm, Ulm, Germany. christian.wolf@uni-ulm.de
authors.forename: Robert Christian
authors.initials: RC
authors.lastname: Wolf
authors.forename: Jochen
authors.initials: J
authors.lastname: Spiess
authors.forename: Nenad
authors.initials: N
authors.lastname: Vasic
authors.forename: Roman
authors.initials: R
authors.lastname: Huber
mesh_terms: D001021:Aortic Valve / Q000000981:diagnostic imaging; D002545:Brain Ischemia / Q000209:etiology*; D017548:Echocardiography, Transesophageal; D005260:Female; D006349:Heart Valve Diseases / Q000150:complications* / Q000000981:diagnostic imaging; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D020521:Stroke / Q000175:diagnosis / Q000209:etiology*