Current trends in live liver donation.
The introduction of living donor liver transplantation (LDLT) has been one of the most remarkable steps in the field of liver transplantation (LT), able to significantly expand the scarce donor pool in countries in which the growing demands of organs are not met by the shortage of available cadaveric grafts. Although the benefits of this procedure are enormous, the physical and psychological sacrifice of the donors is immense, and the expectations for a good outcome for themselves, as well as for the recipients, are high. We report a current overview of the latest trends in live liver donation in its different aspects (i.e. donor's selection, evaluation, operation, morbidity, mortality, ethics and psychology). This review is based on our center's personal experience with almost 200 LDLTs and a detailed analysis of the international literature of the last 7 years about this topic. Knowing in detail how to approach to the different aspects of living liver donation may be helpful in further improve donor's safety and even recipient's outcome.
Nadalin
Silvio
S
Department of General, Visceral and Transplantation Surgery, University Hospital Essen, Essen, Germany. silvio.nadalin@uni-due.de
Malagò
Massimo
M
Radtke
Arnold
A
Erim
Yesim
Y
Saner
Fuat
F
Valentin-Gamazo
Camino
C
Schröder
Tobias
T
Schaffer
Randolph
R
Sotiropoulos
Georgios C
GC
Li
Jun
J
Frilling
Andrea
A
Broelsch
Christoph E
CE
D000293:Adolescent; D000328:Adult; D000533:Altruism; D001787:Blood Group Incompatibility / Q000517:prevention & control; D003068:Coercion; D046148:Donor Selection; D006801:Humans; D007258:Informed Consent; D007430:Intraoperative Care; D008099:Liver / Q000000981:diagnostic imaging; D017114:Liver Failure, Acute / Q000601:surgery; D016031:Liver Transplantation / Q000191:economics / Q000379:methods / Q000639:trends*; D019520:Living Donors / Q000941:ethics / Q000523:psychology; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D011183:Postoperative Complications; D014057:Tomography, X-Ray Computed