title: [Early risk predictors of sudden cardiac death after myocardial infarction: results of follow up of 881 patients].
abstract: BACKGROUND
  It has been shown that depolarization disorders, autonomic dysfunction, and systolic dysfunction of the left ventricle are associated with sudden cardiac death after myocardial infarction.
  
  
  OBJECTIVE
  The objective of study was to examine the prognostic value of the most important predictors in the first week after myocardial infarction.
  
  
  METHODS
  Study included 881 patients who were followed up from 1 to 60 months. During the first week after myocardial infarction, following examination were performed: ECG with standard leads and X, Y, Z orthogonal leads, vectorcardiogram, QT interval, late potentials, short-time spectral analysis of RR variability, nonlinear (Poincaré plot) analysis and echocardiogram.
  
  
  RESULTS
  In univariate analysis, the following parameters measured on the first day were important predictors of sudden cardiac death: lower LF/HF ratio (<1.5) (p = 0.000), T wave inversion in X lead (p = 0.000), high P wave in D2 lead (p=0.030), and diminished systolic function (p = 0.000). In multivariate analysis, the following parameters were significant risk predictors: T wave inversion in X lead, lower LF/HF ratio, positive late potentials and the left ventricle systolic dysfunction.
  
  
  CONCLUSIONS
  The parameters of the left ventricle systolic disfunction with sympathicovagal imbalance and electric instability are the key risk predictors in the first few days after myocardial infarction.
authors.forename: Branislav
authors.initials: B
authors.lastname: Milovanović
authors.forename: Mirjana
authors.initials: M
authors.lastname: Krotin
authors.forename: Dejana
authors.initials: D
authors.lastname: Vuković
authors.forename: Vesna
authors.initials: V
authors.lastname: Bisenić
authors.forename: Tijana
authors.initials: T
authors.lastname: Mirjanić
authors.forename: Slavica
authors.initials: S
authors.lastname: Nikolić
mesh_terms: D016757:Death, Sudden, Cardiac / Q000209:etiology*; D004562:Electrocardiography; D006801:Humans; D009203:Myocardial Infarction / Q000150:complications / Q000503:physiopathology*; D018487:Ventricular Dysfunction, Left / Q000209:etiology / Q000503:physiopathology