title: Tetracycline resistance in group a streptococci: emergence on a global scale and influence on multiple-drug resistance.
abstract: A global sample of group A streptococci (GAS) revealed > or =80 separate acquisitions of tetracycline resistance. Of 244 clones, 38 and 25% displayed resistance to tetracycline and erythromycin, respectively; a relatively high proportion (15%) were resistant to both classes of drugs. tet(M) displayed a highly significant association with erm(B).
authors.affiliation: Department of Microbiology and Immunology, New York Medical College, Valhalla, NY 10595, USA.
authors.forename: Vanessa
authors.initials: V
authors.lastname: Ayer
authors.forename: Wezenet
authors.initials: W
authors.lastname: Tewodros
authors.forename: Anand
authors.initials: A
authors.lastname: Manoharan
authors.forename: Sini
authors.initials: S
authors.lastname: Skariah
authors.forename: Feng
authors.initials: F
authors.lastname: Luo
authors.forename: Debra E
authors.initials: DE
authors.lastname: Bessen
mesh_terms: D024901:Drug Resistance, Multiple, Bacterial; D010802:Phylogeny; D013297:Streptococcus pyogenes / Q000187:drug effects* / Q000235:genetics; D013753:Tetracycline Resistance