Susceptibility and trailing growth of Candida albicans to fluconazole: results of a Korean multicentre study.
The work reported here is the first nationwide, multicenter surveillance study conducted in Korea to obtain data on fluconazole susceptibility of Candida albicans (C. albicans) isolates. A total of 1137 isolates of C. albicans obtained from 17 university hospitals in South Korea during the 6-month period, July through December 2004, were tested. No resistant strains were observed in any of the isolates. Only five of the 1137 isolates (0.44%) of C. albicans were found to be susceptible dose dependent, with all remaining strains (99.56%) susceptible to fluconazole. Trailing growth at 48 h was found in only four isolates (0.35%).
Lee
Mi-Kyung
MK
Kim
Hye-Ryoun
HR
Kang
Jung-Oak
JO
Kim
Mi-Na
MN
Kim
Eui-Chong
EC
Kim
Jae-Seok
JS
Kim
Jin-Ju
JJ
Park
Yeon-Joon
YJ
Song
Wonkeun
W
Shin
Jong-Hee
JH
Lee
Kyu-Man
KM
Lee
Nam-Yong
NY
Lee
Miae
M
Lee
Wee-Gyo
WG
Lee
Chang Kyu
CK
Lee
Hee-Joo
HJ
Chang
Chulhun L
CL
Choi
Tae Yeal
TY
D000935:Antifungal Agents / Q000494:pharmacology*; D002176:Candida albicans / Q000187:drug effects* / Q000254:growth & development* / Q000302:isolation & purification; D002177:Candidiasis / Q000382:microbiology*; D025141:Drug Resistance, Fungal; D015725:Fluconazole / Q000494:pharmacology*; D006785:Hospitals, University; D006801:Humans; D007723:Korea; D008826:Microbial Sensitivity Tests
D000935:Antifungal Agents; D015725:Fluconazole