title: Intralesional cisplatin chemotherapy and topical cryotherapy for the control of choanal squamous cell carcinoma in an African penguin (Spheniscus demersus).
abstract: A 3.5-yr-old, 2.5-kg female African penguin (Spheniscus demersus) was diagnosed with a choanal squamous cell carcinoma on the basis of biopsy after a history of choanal ulceration and anorexia with weight loss. Therapeutic modalities included the use of intralesional cisplatin followed by localized, topical cryotherapy with liquid nitrogen. The penguin remained free of clinical disease for a period of 9 mo, at which time a second cryotreatment was performed. The patient has remained free of all signs of choanal carcinoma for a period of 13 mo since the second cryotreatment.
authors.affiliation: Animal Health Department, Fort Worth Zoological Park, 1989 Colonial Parkway, Fort Worth, Texas 76110, USA.
authors.forename: Shannon T
authors.initials: ST
authors.lastname: Ferrell
authors.forename: Annajane B
authors.initials: AB
authors.lastname: Marlar
authors.forename: Michael
authors.initials: M
authors.lastname: Garner
authors.forename: Nancy P
authors.initials: NP
authors.lastname: Lung
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D001715:Bird Diseases / Q000188:drug therapy / Q000628:therapy*; D002294:Carcinoma, Squamous Cell / Q000188:drug therapy / Q000628:therapy / Q000662:veterinary*; D002945:Cisplatin / Q000627:therapeutic use*; D003131:Combined Modality Therapy / Q000662:veterinary; D017679:Cryotherapy / Q000379:methods / Q000662:veterinary*; D005260:Female; D009303:Nasopharyngeal Neoplasms / Q000188:drug therapy / Q000628:therapy / Q000662:veterinary*; D009364:Neoplasm Recurrence, Local / Q000662:veterinary; D046429:Spheniscidae; D016896:Treatment Outcome
chemical_list: D000970:Antineoplastic Agents; D002945:Cisplatin