The effect of steric bulk in Sonogashira coupling reactions.
The rates of Sonogashira coupling reactions using [Pd-PR(3)] complexes depend on a combination of the steric bulk of phosphines and substrates; however, below a critical cone angle of ca. 170 degrees the catalytic activity drops drastically.
an der Heiden
Markus
M
Anorganische Chemie im Zintl-Institute, TU Darmstadt, Petersenstr. 18, 64287, Darmstadt, Germany.
Plenio
Herbert
H