title: [Prognosis of the syndrome of mild cognitive impairment: the data of the biennial follow-up study].
abstract: Structure and prognostic significance of the syndrome of mild cognitive impairment (MCI) were studied in a prospective biennial study of a randomized cohort of elderly people meeting current MCI criteria. The study comprised 40 patients aged from 50 to 80 years. Clinical follow up study included psychopathological, psychometric, neuropsychological, neuroimaging and molecular genetic (ApoE genotyping) examinations were made. Psychopathological structure and psychometric characteristics of the MCI syndrome are described, and clinical and genetic factors of prognostic value are singled out.
authors.forename: S I
authors.initials: SI
authors.lastname: Gavrilova
authors.forename: Ia B
authors.initials: IaB
authors.lastname: Fedorova
authors.forename: I F
authors.initials: IF
authors.lastname: Roshchina
authors.forename: G I
authors.initials: GI
authors.lastname: Korovaĭtseva
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000483:Alleles; D053327:Apolipoprotein E4 / Q000235:genetics*; D003071:Cognition / Q000502:physiology*; D003072:Cognition Disorders / Q000175:diagnosis / Q000235:genetics / Q000523:psychology; D004247:DNA / Q000235:genetics*; D003937:Diagnosis, Differential; D005260:Female; D005500:Follow-Up Studies; D005838:Genotype; D006801:Humans; D008297:Male; D008875:Middle Aged; D016133:Polymerase Chain Reaction; D011379:Prognosis; D011446:Prospective Studies; D011594:Psychometrics / Q000379:methods*; D012720:Severity of Illness Index; D013577:Syndrome
chemical_list: D053327:Apolipoprotein E4; D004247:DNA