title: Isolated giant xanthogranuloma of the orbit.
abstract: Xanthogranuloma is an uncommon tumor in the orbit and is usually associated with systemic diseases or blood abnormalities. We report an extremely rare presentation of isolated orbital xanthogranuloma unassociated with any systemic disease, hematological or biochemical abnormalities. A 47-year-old physician presented with proptosis of the left eye of three years duration with yellowish skin plaques. The CT scan revealed a well-defined heterogeneous mass in the medial orbit. There was no evidence of systemic, serum or biochemical abnormalities. The mass was removed by a medial orbitotomy. Histopathology confirmed the diagnosis based on the presence of inflammatory infiltrates, histiocytes and Touton giant cells.
authors.affiliation: The Ocular Oncology Service, LV Prasad Eye Institute, Hyderabad, India.
authors.forename: Ramesh
authors.initials: R
authors.lastname: Murthy
authors.forename: Santosh G
authors.initials: SG
authors.lastname: Honavar
authors.forename: Geeta K
authors.initials: GK
authors.lastname: Vemuganti
authors.forename: Milind
authors.initials: M
authors.lastname: Naik
authors.forename: Sanghamitra
authors.initials: S
authors.lastname: Burman
mesh_terms: D003937:Diagnosis, Differential; D005500:Follow-Up Studies; D006099:Granuloma / Q000175:diagnosis* / Q000601:surgery; D006801:Humans; D008875:Middle Aged; D013508:Ophthalmologic Surgical Procedures / Q000379:methods; D009918:Orbital Neoplasms / Q000175:diagnosis* / Q000601:surgery; D014057:Tomography, X-Ray Computed; D014973:Xanthomatosis / Q000175:diagnosis* / Q000601:surgery