Ultra-resolution imaging of a self-assembling biomolecular system using robust carbon nanotube AFM probes.
Nanoscale structural features of a novel self-assembling DNA based nanostructure have been resolved. Image data is of sufficient resolution to allow molecular orientation and the effect of surface adsorption to be characterized. This has been achieved using AFM with probes employing carbon nanotubes attached via a thin film of plasma polymerized hexane. This presents the nanotube with a highly hydrophobic coating to which it can adsorb, increasing production success and probe robustness.
Carnally
Stewart
S
Laboratory of Biophysics and Surface Analysis, School of Pharmacy, The University of Nottingham, Nottingham, NG7 2RD, United Kingdom.
Barrow
Katharine
K
Alexander
Morgan R
MR
Hayes
Christopher J
CJ
Stolnik
Snjezana
S
Tendler
Saul J B
SJ
Williams
Philip M
PM
Roberts
Clive J
CJ
D004247:DNA / Q000737:chemistry; D018625:Microscopy, Atomic Force; D037742:Nanotubes, Carbon / Q000648:ultrastructure*
D037742:Nanotubes, Carbon; D004247:DNA