title: Does raising the glucose challenge test threshold impact birthweight in Asian gravidas?
abstract: OBJECTIVE
  Some authors suggest a glucose challenge test (GCT) threshold of 150 mg/dL in Asian gravidas. The impact of such a policy on outcomes is unknown.
  
  
  METHODS
  A retrospective cohort of 1705 Asian gravidas. Subjects (n=95) had a GCT of 140-150 mg/dL and underwent a 3-h glucose tolerance test (GTT). Matched controls (n=190) had a GCT of <140 mg/dL. Birthweight was the primary outcome and the secondary outcomes were cesarean delivery (CD) rate and macrosomia.
  
  
  RESULTS
  Eight subjects (11.9%) had gestational diabetes mellitus (GDM); none had GTT fasting values of >90 mg/dL. Mean birthweight was 3282 g in the subjects and 3238 g in the controls (P=0.39). There were no significant differences in the secondary outcomes.
  
  
  CONCLUSIONS
  Compared with controls, study patients did not deliver significantly larger infants. However, raising the GCT threshold would have missed 8 subjects (11.9%) with GDM. Raising the GCT threshold to 150 mg/dL in Asian gravidas may unacceptably lower the sensitivity of the screening test.
authors.affiliation: Department of Obstetrics and Gynecology, New York University School of Medicine, New York, NY, USA. nikki.koklanaris@carolinashealthcare.org
authors.forename: Nikki
authors.initials: N
authors.lastname: Koklanaris
authors.forename: Clarissa
authors.initials: C
authors.lastname: Bonnano
authors.forename: David
authors.initials: D
authors.lastname: Seubert
authors.forename: Yuzuru
authors.initials: Y
authors.lastname: Anzai
authors.forename: Richard
authors.initials: R
authors.lastname: Jennings
authors.forename: Men-Jean
authors.initials: MJ
authors.lastname: Lee
mesh_terms: D000328:Adult; D044466:Asian People; D001724:Birth Weight / Q000502:physiology*; D016640:Diabetes, Gestational / Q000175:diagnosis* / Q000208:ethnology* / Q000503:physiopathology; D005260:Female; D005951:Glucose Tolerance Test; D006801:Humans; D011247:Pregnancy; D012189:Retrospective Studies