Neuronal calcium sensor proteins: generating diversity in neuronal Ca2+ signalling.
In neurons, intracellular calcium signals have crucial roles in activating neurotransmitter release and in triggering alterations in neuronal function. Calmodulin has been widely studied as a Ca(2+) sensor that has several defined roles in neuronal Ca(2+) signalling, but members of the neuronal calcium sensor protein family have also begun to emerge as key components in a number of regulatory pathways and have increased the diversity of neuronal Ca(2+) signalling pathways. The differing properties of these proteins allow them to have discrete, non-redundant functions.
Burgoyne
Robert D
RD
The Physiological Laboratory, School of Biomedical Sciences, University of Liverpool, UK. burgoyne@liv.ac.uk
D000818:Animals; D001921:Brain / Q000166:cytology; D002118:Calcium / Q000378:metabolism*; D020013:Calcium Signaling / Q000502:physiology*; D006801:Humans; D008958:Models, Molecular; D008959:Models, Neurological; D051580:Neuronal Calcium-Sensor Proteins / Q000502:physiology*; D009474:Neurons / Q000502:physiology*
D051580:Neuronal Calcium-Sensor Proteins; D002118:Calcium