[Effect of preparation on the major chemical constituents of Polygonum multiflorum].
OBJECTIVE
To study the dynamic changes of Emodin, Physcion, Emodin-8-O-beta-D-glucopyranoside, Physcion-8-O-beta-D-glucopyranoside and 2,3,5,4'-tetrahydtoxysilbene-2-O-beta-D-glucopyranoside in Polygonum multiflorum during preparation and analyze their changing laws.


METHODS
Five major constituents before and after preparation were determined by RP-HPLC methods.


RESULTS
The five ingredients decreased significantly after preparation.


CONCLUSIONS
The major chemical constituents of Polygonum multiflorum decrease significantly, suggesting the necessarity of prepared Polygonum multiflorum in clinical application worth studying.
Zhang
Zhi-guo
ZG
Department of Pharmacy, The 88th Hospital of PLA, Tai' an 271000, China.
Lü
Tai-sheng
TS
Yao
Qing-qiang
QQ
D000880:Anthraquinones / Q000032:analysis* / Q000302:isolation & purification; D002851:Chromatography, High Pressure Liquid / Q000379:methods; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification; D004642:Emodin / Q000031:analogs & derivatives* / Q000032:analysis* / Q000302:isolation & purification; D000431:Ethanol; D005960:Glucosides / Q000032:analysis / Q000302:isolation & purification; D006358:Hot Temperature; D035281:Plant Tubers / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry; D028502:Polygonum / Q000737:chemistry*; D013267:Stilbenes / Q000032:analysis / Q000302:isolation & purification; D013678:Technology, Pharmaceutical / Q000379:methods*; D013997:Time Factors
D000880:Anthraquinones; D004365:Drugs, Chinese Herbal; D005960:Glucosides; D013267:Stilbenes; D000431:Ethanol; D004642:Emodin