title: Advances in hormonal therapy for breast cancer.
abstract: OBJECTIVE
  To describe recent developments in hormonal therapy for breast cancer, focusing on SERMs and AIs.
  
  
  METHODS
  Published journal articles and texts, research reports and monographs, government publications, and professional organization guidelines.
  
  
  CONCLUSIONS
  Research continues to identify the effectiveness of hormonal therapy in breast cancer, including adjuvant treatment in early and advanced stages as well as a chemopreventive measure. The individual drug profile must be evaluated for safety and efficacy, and the impact on QOL must be considered.
  
  
  CONCLUSIONS
  It is imperative that oncology nurses understand the physiology, application, risks, and benefits of hormonal therapies.
authors.affiliation: UCLA School of Nursing, Los Angeles, usa. nbush@premiereoncology.com
authors.forename: Nancy Jo
authors.initials: NJ
authors.lastname: Bush
mesh_terms: D018931:Antineoplastic Agents, Hormonal / Q000009:adverse effects / Q000627:therapeutic use*; D001943:Breast Neoplasms / Q000188:drug therapy* / Q000451:nursing; D004967:Estrogens / Q000502:physiology; D005260:Female; D006801:Humans
chemical_list: D018931:Antineoplastic Agents, Hormonal; D004967:Estrogens