Pathological findings following trigeminal neuralgia radiosurgery.
Autopsy, 3D MRI and histopathological findings are presented in a patient who had suffered from trigeminal neuralgia and was treated two times by radiosurgery. The first treatment was performed with 90 Gy at the distal part of the nerve. Because of recurrent pain, a second irradiation was carried out delivering 70 Gy at a more proximal segment of the nerve 10 months later. The patient died from a hemorrhagic stroke 26 days following the second intervention. Autopsy revealed a neurovascular conflict close to the second radiosurgery shot. Histopathology demonstrated acute and chronic stage radiation-induced lesions in the trigeminal nerve.
Szeifert
György T
GT
Centre Gamma Knife, Hôpital Académique Erasme, Université Libre de Bruxelles, Brussels, Belgium.
Salmon
Isabelle
I
Lorenzoni
José
J
Massager
Nicolas
N
Levivier
Marc
M
D001344:Autopsy; D002536:Cerebral Arteries / Q000002:abnormalities / Q000473:pathology; D005355:Fibrosis; D006801:Humans; D016634:Radiosurgery; D014277:Trigeminal Neuralgia / Q000473:pathology* / Q000601:surgery*