title: Design and synthesis of metal-free artificial ribonucleases.
abstract: The present review is aimed at giving a general overview of our results in the field of designing and synthesizing simple peptide-like molecules that mimic structural and functional aspects of natural ribonucleases, as well as designing oligonucleotide-based artificial ribonucleases.
authors.affiliation: Institute of Chemical Biology and Fundamental Medicine, Novosibirsk, Russia. koroleva@niboch.nsc.ru
authors.forename: Ludmila S
authors.initials: LS
authors.lastname: Koroleva
authors.forename: Inna Yu
authors.initials: IY
authors.lastname: Serpokrylova
authors.forename: Valentin V
authors.initials: VV
authors.lastname: Vlassov
authors.forename: Vladimir N
authors.initials: VN
authors.lastname: Silnikov
mesh_terms: D000595:Amino Acid Sequence; D001483:Base Sequence; D008670:Metals / Q000737:chemistry; D008958:Models, Molecular; D008969:Molecular Sequence Data; D009690:Nucleic Acid Conformation; D009841:Oligonucleotides / Q000737:chemistry / Q000378:metabolism; D010455:Peptides / Q000138:chemical synthesis* / Q000737:chemistry; D012313:RNA / Q000737:chemistry / Q000378:metabolism; D012260:Ribonucleases / Q000138:chemical synthesis* / Q000737:chemistry / Q000378:metabolism; D013379:Substrate Specificity
chemical_list: D008670:Metals; D009841:Oligonucleotides; D010455:Peptides; D012313:RNA; D012260:Ribonucleases