Acute upper airway obstruction from acquired angioedema.
C1 esterase inhibitor deficiency is an unusual cause of acute upper airway angioedema. This case of angioedema is secondary to acquired C1 esterase inhibitor deficiency associated with neoplastic disease and triggered by the use of angiotensin converting enzyme inhibitors. It was sufficiently severe to require emergency airway management. A guide to the evaluation and management of angioedema is presented.
Cheng
William Yc
WY
Royal Adelaide Hospital and University of Adelaide, Adelaide, South Australia, Australia.
Smith
William B
WB
Russell
W John
WJ
D000368:Aged; D000402:Airway Obstruction / Q000209:etiology* / Q000628:therapy; D000799:Angioedema / Q000139:chemically induced* / Q000150:complications*; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000009:adverse effects*; D050718:Complement C1 Inhibitor Protein / Q000378:metabolism*; D005260:Female; D006801:Humans; D007442:Intubation, Intratracheal; D017257:Ramipril / Q000009:adverse effects*; D014060:Tongue Diseases / Q000150:complications
D000806:Angiotensin-Converting Enzyme Inhibitors; D050718:Complement C1 Inhibitor Protein; D017257:Ramipril