Otological toxicity after postoperative radiotherapy for parotid tumours.
Radiotherapy is commonly used in the management of malignant parotid gland tumours that have adverse pathological risk factors after surgery. Radiation to the parotid bed is associated with predictable complications. In particular, the close proximity of the auditory apparatus, which receives a significant radiation dose, results in significant toxicity in a proportion of patients. Here we review auditory toxicity after radiation to the parotid bed.
Bhide
S A
SA
Head and Neck Unit, Institute of Cancer Research and Royal Marsden Hospital, Fulham Road, London SW3 6JJ, UK. shree.bhide@rmh.nhs.uk
Harrington
K J
KJ
Nutting
C M
CM
D000970:Antineoplastic Agents / Q000009:adverse effects; D003131:Combined Modality Therapy; D004307:Dose-Response Relationship, Radiation; D004423:Ear / Q000528:radiation effects*; D006319:Hearing Loss, Sensorineural / Q000209:etiology; D006801:Humans; D010306:Parotid Gland / Q000528:radiation effects*; D010307:Parotid Neoplasms / Q000188:drug therapy / Q000532:radiotherapy* / Q000601:surgery; D011832:Radiation Injuries / Q000209:etiology*; D011878:Radiotherapy / Q000009:adverse effects
D000970:Antineoplastic Agents