Virtually epimerization-free synthesis of peptide-alpha-thioesters.
Under slightly basic or neutral reaction conditions peptide-alpha-thioesters are photochemically synthesized from peptide-alpha-nitroindoline precursors, either in solution, or by direct photorelease from a solid support.
Hogenauer
Tyrone J
TJ
Department of Chemistry, University of Texas at El Paso, El Paso, TX 79902, USA.
Wang
Qianli
Q
Sanki
Aditya K
AK
Gammon
Amy J
AJ
Chu
Cherie H L
CH
Kaneshiro
Clyde M
CM
Kajihara
Yasuhiro
Y
Michael
Katja
K
D000596:Amino Acids / Q000737:chemistry; D002851:Chromatography, High Pressure Liquid; D004952:Esters; D005449:Fluorenes / Q000737:chemistry; D007211:Indoles / Q000737:chemistry; D015394:Molecular Structure; D010455:Peptides / Q000138:chemical synthesis* / Q000737:chemistry; D010777:Photochemistry; D013438:Sulfhydryl Compounds / Q000138:chemical synthesis* / Q000737:chemistry
D000596:Amino Acids; D004952:Esters; D005449:Fluorenes; D007211:Indoles; D010455:Peptides; D013438:Sulfhydryl Compounds