title: Depression, night terrors, and insomnia associated with long-term intrathecal clonidine therapy.
abstract: Intraspinal clonidine is an effective adjunct to intrathecal/epidural opioid administration. We report a case of neuropathic pain treated with intraspinal analgesics in which depression, insomnia, and night terrors developed in association with intraspinal clonidine.
authors.affiliation: Anesthesiology Service, Madison VAMC, Department of Anesthesiology, University of Wisconsin, Madison, Wisconsin, USA. brian.bevacqua2@med.va.gov
authors.forename: Brian K
authors.initials: BK
authors.lastname: Bevacqua
authors.forename: Maher
authors.initials: M
authors.lastname: Fattouh
authors.forename: Misha
authors.initials: M
authors.lastname: Backonja
mesh_terms: D000368:Aged; D000700:Analgesics / Q000008:administration & dosage / Q000627:therapeutic use; D017545:Aortic Aneurysm, Thoracic / Q000601:surgery*; D002404:Catheterization; D003000:Clonidine / Q000008:administration & dosage / Q000627:therapeutic use; D006801:Humans; D008297:Male; D009443:Neuritis / Q000188:drug therapy / Q000209:etiology; D010149:Postoperative Pain / Q000188:drug therapy*; D010264:Paraplegia / Q000209:etiology; D011183:Postoperative Complications; D013119:Spinal Cord Injuries / Q000503:physiopathology; D013346:Subarachnoid Space; D016896:Treatment Outcome
chemical_list: D000700:Analgesics; D003000:Clonidine