Cronkhite-Canada syndrome associated with schizophrenia.
Here, we report a case of Cronkhite-Canada syndrome in a patient with schizophrenia. A 64-year-old man, who had been diagnosed as having a schizophrenic disorder at the age of 30, presented with alopecia, atrophic nail changes, hyperpigmentation of the skin, and inflammatory polyposis of the stomach and colon. Endoscopic ultrasonography of the stomach and colon revealed diffuse mucosal thickening with small hypoechoic areas, corresponding to edema of the lamina propria. After treatment with parenteral hyperalimentation and tranexamic acid, his physical findings and polyposis gradually improved. This is the first report of Cronkhite-Canada syndrome in a patient with schizophrenia.
Nakayama
Masaharu
M
Department of Advanced Molecular and Cell Therapy, Kyushu University Hospital, Fukuoka, Japan.
Muta
Hiromi
H
Somada
Shinichi
S
Maeda
Toyoki
T
Mutoh
Toshitaka
T
Shimizu
Kanako
K
Suehiro
Yoko
Y
Hisano
Terumasa
T
Kurita
Ryo
R
Shiraishi
Takeshi
T
Mori
Masaki
M
Yoshikawa
Yasuji
Y
Tsunetomi
Nobuto
N
Uchida
Akihiro
A
Tani
Kenzaburo
K
D000505:Alopecia / Q000175:diagnosis / Q000628:therapy; D003113:Colonoscopy; D003131:Combined Modality Therapy; D003967:Diarrhea / Q000175:diagnosis / Q000628:therapy; D019160:Endosonography / Q000379:methods; D005500:Follow-Up Studies; D006801:Humans; D017495:Hyperpigmentation / Q000175:diagnosis / Q000628:therapy; D044483:Intestinal Polyposis / Q000150:complications* / Q000175:diagnosis* / Q000628:therapy; D008297:Male; D008875:Middle Aged; D018570:Risk Assessment; D012559:Schizophrenia / Q000150:complications* / Q000175:diagnosis* / Q000628:therapy