Hepatotoxicity due to a drug interaction between amodiaquine plus artesunate and efavirenz.
German
Polina
P
Greenhouse
Bryan
B
Coates
Carrie
C
Dorsey
Grant
G
Rosenthal
Philip J
PJ
Charlebois
Edwin
E
Lindegardh
Niklas
N
Havlir
Diane
D
Aweeka
Francesca T
FT
D000328:Adult; D000480:Alkynes; D000655:Amodiaquine / Q000009:adverse effects* / Q000627:therapeutic use; D037621:Artemisinins / Q000009:adverse effects* / Q000627:therapeutic use; D000077332:Artesunate; D048588:Benzoxazines; D056486:Chemical and Drug Induced Liver Injury; D015331:Cohort Studies; D003521:Cyclopropanes; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D004347:Drug Interactions; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D008107:Liver Diseases / Q000201:enzymology; D008111:Liver Function Tests; D008297:Male; D008875:Middle Aged; D010078:Oxazines / Q000009:adverse effects* / Q000627:therapeutic use; D012016:Reference Values; D018570:Risk Assessment; D012717:Sesquiterpenes / Q000009:adverse effects* / Q000627:therapeutic use; D000637:Transaminases / Q000097:blood
D000480:Alkynes; D037621:Artemisinins; D048588:Benzoxazines; D003521:Cyclopropanes; D010078:Oxazines; D012717:Sesquiterpenes; D000655:Amodiaquine; D000077332:Artesunate; D000637:Transaminases; C098320:efavirenz