title: Efficacy of treating children with anterior commissure and true vocal fold respiratory papilloma with the 585-nm pulsed-dye laser.
abstract: OBJECTIVE
  To report preliminary results regarding the safety and efficacy of the 585-nm pulsed-dye laser (PDL) for the treatment of juvenile-onset recurrent respiratory papillomatosis (JORRP) in the pediatric population.
  
  
  METHODS
  Prospective longitudinal cohort study.
  
  
  METHODS
  Two pediatric otolaryngology referral centers.
  
  
  METHODS
  Twenty-three pediatric patients ranging in age from 6 months to 17 years.
  
  
  METHODS
  The 585-nm PDL was used for at least 1 treatment on each of these patients to treat JORRP of the true vocal folds or anterior commissure.
  
  
  METHODS
  Complications from the use of the 585-nm PDL in the treatment of JORRP.
  
  
  RESULTS
  There was no evidence of anterior commissure webbing or true vocal fold scarring in this group of 23 patients followed up for 3 months to 1 year.
  
  
  CONCLUSIONS
  The 585-nm PDL seems to be a safe instrument for treatment of JORRP. There is the potential that improved voice outcomes may be apparent when compared with traditional therapies because the vocal fold epithelium seems to be unharmed when treated with this method. Furthermore, the lack of epithelial damage incurred by the 585-nm PDL should enable more aggressive surgical excision of anterior commissure disease. Further prospective longitudinal studies examining voice outcomes are needed.
authors.affiliation: Department of Otolaryngology, Massachusetts Eye and Ear Infirmary, Boston 02114, USA. Christopher_Hartnick@meei.harvard.edu
authors.forename: Christopher J
authors.initials: CJ
authors.lastname: Hartnick
authors.forename: Mark E
authors.initials: ME
authors.lastname: Boseley
authors.forename: Ramon A
authors.initials: RA
authors.lastname: Franco
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Cunningham
authors.forename: Seth
authors.initials: S
authors.lastname: Pransky
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D007822:Laryngeal Neoplasms / Q000601:surgery*; D053685:Laser Therapy / Q000009:adverse effects / Q000379:methods; D008297:Male; D010212:Papilloma / Q000601:surgery*; D011183:Postoperative Complications / Q000453:epidemiology*; D011446:Prospective Studies; D014827:Vocal Cords / Q000473:pathology* / Q000601:surgery