Successful treatment of mandibular squamous cell carcinoma in a Malayan sun bear (Helarctos malayanus).
An adult, female Malayan sun bear (Helarctos malayanus) was diagnosed with squamous cell carcinoma of the rostral mandible. Initial treatment included bilateral mandibulectomy rostral to the lingual frenulum followed by intra- and perilesional cisplatin injections. Recovery after the procedure was uneventful and the Malayan sun bear adapted well to a shortened mandible. Histopathology indicated incomplete surgical excision of the tumor; therefore, radiation therapy was instituted weekly for four treatments at 2 Gy in parallel opposed fields (total 4 Gy each treatment) with one additional cisplatin treatment. Two years after initial presentation, the animal showed no recurrence of neoplasia.
Mylniczenko
Natalie D
ND
Lincoln Park Zoo, 2001 North Clark Street, Chicago, Illinois 60614, USA.
Manharth
Ann L
AL
Clayton
Leigh Ann
LA
Feinmehl
Rhonda
R
Robbins
Mitch
M
D000818:Animals; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D002294:Carcinoma, Squamous Cell / Q000188:drug therapy / Q000601:surgery / Q000662:veterinary*; D002945:Cisplatin / Q000627:therapeutic use*; D005260:Female; D008296:Malaysia; D008339:Mandibular Neoplasms / Q000188:drug therapy / Q000601:surgery / Q000662:veterinary*; D016896:Treatment Outcome; D001503:Ursidae
D000970:Antineoplastic Agents; D002945:Cisplatin