title: Tumor lysis associated with sudden onset of syndrome of inappropriate antidiuretic hormone secretion.
abstract: Syndrome of inappropriate antidiuretic hormone secretion is frequent in small-cell lung carcinomas. We report on a case of syndrome of inappropriate antidiuretic hormone secretion after each of the first 2 cycles of chemotherapy for small-cell lung cancer. The association with chemotherapy-induced tumor lysis is proposed, particularly based on the course of antidiuretic hormone levels, and a review of the literature is presented. Syndrome of inappropriate antidiuretic hormone secretion can occur during tumor lysis syndrome.
authors.affiliation: Service d'Oncologie Medicale, Hopital Avicenne, Assistance Publique Hpôitaux de Paris, Bobigny, France. pierre.saintigny@avc.ap-hop-paris.fr
authors.forename: Pierre
authors.initials: P
authors.lastname: Saintigny
authors.forename: Kader
authors.initials: K
authors.lastname: Chouahnia
authors.forename: Régis
authors.initials: R
authors.lastname: Cohen
authors.forename: Marie-Christine
authors.initials: MC
authors.lastname: Pailler
authors.forename: Jeanne-Marie
authors.initials: JM
authors.lastname: Brechot
authors.forename: Jean-François
authors.initials: JF
authors.lastname: Morere
authors.forename: Jean-Luc
authors.initials: JL
authors.lastname: Breau
mesh_terms: D018288:Carcinoma, Small Cell / Q000150:complications / Q000188:drug therapy*; D006801:Humans; D007177:Inappropriate ADH Syndrome / Q000209:etiology*; D008175:Lung Neoplasms / Q000150:complications / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D010257:Paraneoplastic Syndromes / Q000209:etiology*; D015275:Tumor Lysis Syndrome / Q000150:complications*; D014667:Vasopressins / Q000097:blood
chemical_list: D014667:Vasopressins