title: [Impact of tobacco use on the periodontium--an update (I)--Part 1: Epidemiologic und pathogenetic aspects of tobacco-related periodontal diseases].
abstract: This literature review represents the second in a series of articles from the Swiss task force "Smoking--Intervention in the private dental office" on the topic "tobacco use and dental medicine". In this article, the epidemiological background as well as some pathogenetic processes are described and discussed critically for tobacco-related periodontal diseases. Earlier publications confirmed tobacco consumption as a risk factor for periodontal diseases. Over the last few years, oral health research has significantly contributed to the understanding of the mechanisms leading to the deterioration of the hard and soft tissues supporting the teeth. With the recording of the number of cigarettes smoked per day and the amount of years tobacco was used, a dose response relationship was established. Various, potentially significant pathogenic effects of tobacco-related substances may exist on the periodontal tissues, the immune response system or the composition of the oral flora. Moreover, there is reference that tobacco consumption may change the genetically determined susceptibility for periodontal diseases.
authors.affiliation: Klinik für Parodontologie, Endodontologie und Kariologie, Universitätskliniken für Zahnmedizin, Basel. clemens.walter@unibas.ch
authors.forename: Clemens
authors.initials: C
authors.lastname: Walter
authors.forename: Ulrich P
authors.initials: UP
authors.lastname: Saxer
authors.forename: Michael M
authors.initials: MM
authors.lastname: Bornstein
authors.forename: Karl
authors.initials: K
authors.lastname: Klingler
authors.forename: Christoph A
authors.initials: CA
authors.lastname: Ramseier
mesh_terms: D004730:Endothelium, Vascular / Q000187:drug effects; D020022:Genetic Predisposition to Disease; D006801:Humans; D009504:Neutrophils / Q000187:drug effects; D009538:Nicotine / Q000009:adverse effects; D018722:Nicotinic Agonists / Q000009:adverse effects; D010510:Periodontal Diseases / Q000209:etiology* / Q000382:microbiology; D012307:Risk Factors; D012907:Smoking / Q000009:adverse effects* / Q000453:epidemiology; D013557:Switzerland / Q000453:epidemiology; D014028:Tobacco Smoke Pollution / Q000009:adverse effects; D014026:Nicotiana
chemical_list: D018722:Nicotinic Agonists; D014028:Tobacco Smoke Pollution; D009538:Nicotine