Highly selective copper-catalyzed ring expansion of vinyl thiiranes: application to synthesis of biotin and the heterocyclic core of plavix.
Rogers
Erik
E
Department of Chemistry and Chemical Biology, Baker Laboratory, Cornell University, Ithaca, New York 14853-1301, USA.
Araki
Hiroshi
H
Batory
Lindsay A
LA
McInnis
Christine E
CE
Njardarson
Jon T
JT
D001710:Biotin / Q000138:chemical synthesis*; D002384:Catalysis; D000077144:Clopidogrel; D003300:Copper / Q000737:chemistry; D006571:Heterocyclic Compounds / Q000138:chemical synthesis*; D013440:Sulfides / Q000737:chemistry*; D013876:Thiophenes / Q000138:chemical synthesis; D013988:Ticlopidine / Q000031:analogs & derivatives* / Q000138:chemical synthesis; D014753:Vinyl Compounds / Q000737:chemistry
D006571:Heterocyclic Compounds; D013440:Sulfides; D013876:Thiophenes; D014753:Vinyl Compounds; D001710:Biotin; D003300:Copper; C013523:ethylene sulfide; D000077144:Clopidogrel; D013988:Ticlopidine