title: Synthesis and biological properties of 4-(3H)-quinazolone derivatives.
abstract: A new quinazolone series has been designed, and synthesized by the anthranilic acid and different acid derivatives. Their structures have been elucidated on the basis of elemental analyses and spectral studies (IR, (1)H NMR, FT-IR and FAB-MS). A preliminary radiolabelling study with technetium has shown a very good future prospect for further evaluation in vivo. The biological activities (antifungal, antibacterial as well as anticancerous) of the evaluated compounds are discussed in this article.
authors.affiliation: Nanotech and Stem Cell Research, Division of Radiopharmaceuticals, Institute of Nuclear Medicine and Allied Sciences, Brig. S.K. Mazumdar Road, Delhi-110054, India.
authors.forename: Anjani K
authors.initials: AK
authors.lastname: Tiwari
authors.forename: Vinay Kumar
authors.initials: VK
authors.lastname: Singh
authors.forename: Aruna
authors.initials: A
authors.lastname: Bajpai
authors.forename: Gauri
authors.initials: G
authors.lastname: Shukla
authors.forename: Sweta
authors.initials: S
authors.lastname: Singh
authors.forename: Anil K
authors.initials: AK
authors.lastname: Mishra
mesh_terms: D000900:Anti-Bacterial Agents / Q000138:chemical synthesis* / Q000494:pharmacology*; D008826:Microbial Sensitivity Tests; D011799:Quinazolines / Q000138:chemical synthesis* / Q000494:pharmacology*; D013057:Spectrum Analysis
chemical_list: D000900:Anti-Bacterial Agents; D011799:Quinazolines