Relationship between the fibroblastic behaviour and surface properties of RGD-immobilized PCL membranes.
In this study, poly-epsilon-caprolactone (PCL) membranes were modified with the cell adhesive peptide RGD by chemical immobilization technique. The roughness and hydrophilicity were increased after RGD immobilization and an improved cell attachment was observed.
Karakecili
A
A
Chemical Engineering Dept., Hacettepe University, 06532, Beytepe, Ankara, Turkey.
Satriano
C
C
Gumusderelioglu
M
M
Marletta
G
G
D000042:Absorption; D001672:Biocompatible Materials / Q000008:administration & dosage / Q000737:chemistry; D002448:Cell Adhesion / Q000187:drug effects / Q000502:physiology; D018929:Cell Culture Techniques / Q000379:methods; D002460:Cell Line; D049109:Cell Proliferation / Q000187:drug effects; D002470:Cell Survival / Q000187:drug effects; D003460:Crystallization / Q000379:methods; D005347:Fibroblasts / Q000166:cytology* / Q000187:drug effects / Q000502:physiology*; D006801:Humans; D008422:Materials Testing; D009842:Oligopeptides / Q000737:chemistry* / Q000494:pharmacology*; D011091:Polyesters / Q000737:chemistry*; D013223:Statistics as Topic; D013499:Surface Properties; D023822:Tissue Engineering / Q000379:methods*
D001672:Biocompatible Materials; D009842:Oligopeptides; D011091:Polyesters; C016240:polycaprolactone; C047981:arginyl-glycyl-aspartic acid