title: Lymph node recurrence following stage IA vulvar carcinoma: two cases and a short overview of literature.
abstract: Stage IA vulvar carcinoma is not supposed to metastasize to the lymph nodes. Therefore, it is assumed that these lesions can be safely treated by less aggressive methods than macroinvasive carcinomas. However, in this case report, two patients are described who had vulvar lesions with a depth of invasion of less than 1 mm and developed lymph node metastases in the groin despite radical wide local excision of their lesions. Both the patients underwent lymphadenectomy and received postoperative radiation therapy on the groins. Neither of the two patients died of vulvar carcinoma. Thus, we conclude that vigilance for the occurrence of lymph node metastases remains necessary after radical, local excision in stage IA vulvar cancer. However, this case report also shows that adequate treatment of groin node metastases can result in a very good long-term survival.
authors.affiliation: Department of Gynecological Surgery and Oncology, University Medical Centre Utrecht, Utrecht, The Netherlands. f.vernooij@umcutrecht.nl
authors.forename: F
authors.initials: F
authors.lastname: Vernooij
authors.forename: D M D S
authors.initials: DM
authors.lastname: Sie-Go
authors.forename: A P M
authors.initials: AP
authors.lastname: Heintz
mesh_terms: D000369:Aged, 80 and over; D002277:Carcinoma / Q000473:pathology*; D005260:Female; D006801:Humans; D008197:Lymph Node Excision; D008207:Lymphatic Metastasis; D008875:Middle Aged; D012008:Recurrence; D014846:Vulvar Neoplasms / Q000473:pathology*