Gradient magnetic-field topography for dynamic changes of epileptic discharges.
We developed gradient magnetic-field topography (GMFT) for magnetoencephalography (MEG). We plotted the Euclidean norms of gradient magnetic fields occurring at the centers of 102 sensors onto 49-point grids and projected these norms onto the MRI brain surface of a 12-year-old boy who presented with neocortical epilepsy secondary to a left temporal tumor. The peak gradient magnetic field located posterior to the tumor and correlated to MEG dipoles. The gradient magnetic field propagated to the temporo-parietal region and corresponded with spike locations on electrocorticography. GMFT revealed the location and distribution of spikes while avoiding the inverse problem.
Hashizume
Akira
A
Department of Neurosurgery, Graduate School of Biomedical Sciences, Hiroshima University, 1-2-3 Kasumi, Hiroshima, 734-8551, Japan.
Iida
Koji
K
Shirozu
Hiroshi
H
Hanaya
Ryosuke
R
Kiura
Yoshihiro
Y
Kurisu
Kaoru
K
Otsubo
Hiroshi
H
D001931:Brain Mapping; D002648:Child; D004833:Epilepsy, Temporal Lobe / Q000473:pathology / Q000503:physiopathology*; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D015225:Magnetoencephalography; D008297:Male; D017711:Nonlinear Dynamics