Transplacental passage of non-ionic contrast agents resulting in fetal bowel opacification: a mimic of pneumoperitoneum in the newborn.
Although animal studies suggest that non-ionic radiological contrast agents do not cross the placenta, case reports have documented transplacental passage of the non-ionic monomers iohexol and iopromide in humans. We report a case of presumed transplacental passage of the non-ionic monomer ioversol resulting in fetal bowel opacification and mimicking pneumoperitoneum.
Hill
Brook J
BJ
Department of Radiology, University of Miami Miller School of Medicine, Miami, FL 33136, USA.
Saigal
Gaurav
G
Patel
Sandip
S
Abdenour
George E
GE
D000328:Adult; D003287:Contrast Media / Q000009:adverse effects*; D003937:Diagnosis, Differential; D004108:Dilatation, Pathologic / Q000139:chemically induced; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007410:Intestinal Diseases / Q000139:chemically induced* / Q000000981:diagnostic imaging; D008297:Male; D008431:Maternal-Fetal Exchange; D011027:Pneumoperitoneum / Q000175:diagnosis*; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects / Q000139:chemically induced* / Q000000981:diagnostic imaging; D011655:Pulmonary Embolism / Q000000981:diagnostic imaging; D011859:Radiography; D012007:Rectum / Q000000981:diagnostic imaging; D014283:Triiodobenzoic Acids / Q000009:adverse effects*; D014839:Vomiting / Q000139:chemically induced
D003287:Contrast Media; D014283:Triiodobenzoic Acids; C054871:ioversol