title: Paraganglioma of the skull base: a case report.
abstract: Paragangliomas are rare benign neuroendocrine tumors derived from the extra-adrenal paraganglia of the autonomic nervous system. Here, we described a new case of a 75-year-old woman with paraganglioma arising in the middle and posterior cranial fossa with extended destruction of the skull base and clivus. She was admitted to our department with the complaint of severe respiratory distress due to vocal cord paralysis. We discussed its clinical, radiological, histopathological features and treatment modalities in the light of the current literature.
authors.affiliation: Mersin University School of Medicine, Department of Otolaryngology, Mersin, Turkey. munal@mersin.edu.tr
authors.forename: Murat
authors.initials: M
authors.lastname: Unal
authors.forename: Ayşe
authors.initials: A
authors.lastname: Polat
authors.forename: Yavuz Selim
authors.initials: YS
authors.lastname: Pata
authors.forename: Yusuf
authors.initials: Y
authors.lastname: Vayisoğlu
authors.forename: Altan
authors.initials: A
authors.lastname: Yildiz
authors.forename: Onur
authors.initials: O
authors.lastname: Ismi
mesh_terms: D000368:Aged; D014408:Biomarkers, Tumor / Q000032:analysis; D001706:Biopsy; D053379:Chromogranin A / Q000032:analysis; D004724:Endoscopy; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D010235:Paraganglioma / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D012131:Respiratory Insufficiency / Q000209:etiology; D009418:S100 Proteins / Q000032:analysis; D019291:Skull Base / Q000473:pathology; D019292:Skull Base Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D016708:Synaptophysin / Q000032:analysis; D014057:Tomography, X-Ray Computed; D014826:Vocal Cord Paralysis / Q000209:etiology
chemical_list: D014408:Biomarkers, Tumor; D053379:Chromogranin A; D009418:S100 Proteins; D016708:Synaptophysin