Magnifying endoscopy with narrow band imaging for diagnosis of colorectal tumors.
BACKGROUND
Narrow band imaging (NBI) uses optical filters for red-green-blue sequential illumination and narrows the bandwidth of spectral transmittance.


OBJECTIVE
This study aimed to clarify the clinical usefulness of NBI magnification in assessment of pit patterns for diagnosis of colorectal tumors.


METHODS
This was a retrospective study.


METHODS
Department of Endoscopy, Hiroshima University Hospital.


METHODS
A total of 148 colorectal lesions, 16 hyperplasias, 84 tubular adenomas, and 48 early carcinomas were examined and diagnosed histologically. Mean size of lesions was 15.6+/-7.28 mm. Lesions were observed first under NBI magnification without chromoendoscopy and then under standard magnification with chromoendoscopy, and pit patterns were recorded. Results of NBI magnification were compared with those of standard magnification with chromoendoscopy to assess the clinical usefulness of NBI magnification for diagnosing colorectal neoplasia.


RESULTS
Correspondence between the two diagnostic methods was 88% (14/16) for type II, 100% (2/2) for type IIIs, 98% (73/75) for type IIIl, 88% (7/8) for type IV, 78% (25/32) for type Vi, and 100% (3/3) for type Vn pit patterns. NBI depicted brownish change on the basis of surface capillaries in 6% (1/16) of hyperplasia and 99% (83/84) of tubular adenomas. This difference in color depiction was significant.


CONCLUSIONS
This study was performed in single center.


CONCLUSIONS
Determination of pit patterns of colorectal neoplasias by NBI magnification was nearly the same as that by standard magnification with chromoendoscopy. Furthermore, NBI can distinguish neoplastic and nonneoplastic lesions without chromoendoscopy.
Hirata
Mayuko
M
Department of Medicine and Molecular Science, Graduate School of Biomedical Science, Health Service Center, Hiroshima University, Hiroshima, Japan.
Tanaka
Shinji
S
Oka
Shiro
S
Kaneko
Iwao
I
Yoshida
Shigeto
S
Yoshihara
Masaharu
M
Chayama
Kazuaki
K
D020685:Colonoscopes; D003113:Colonoscopy / Q000379:methods*; D015179:Colorectal Neoplasms / Q000473:pathology*; D004396:Coloring Agents; D003937:Diagnosis, Differential; D004867:Equipment Design; D005336:Fiber Optic Technology / Q000295:instrumentation; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D007203:Indigo Carmine; D007413:Intestinal Mucosa / Q000473:pathology; D009361:Neoplasm Invasiveness; D015203:Reproducibility of Results; D012189:Retrospective Studies; D014741:Video Recording
D004396:Coloring Agents; D007203:Indigo Carmine