Zollinger Ellison syndrome, treated with lansoprazole, during pregnancy.
BACKGROUND
Zollinger Ellison syndrome (ZES), an ulcerative disease of the upper gastrointestinal tract that involves the production of high levels of gastrin and gastric acid, is a rare, symptomatic, endocrine neoplastic disease.


METHODS
We report a rare case of gastrinoma that was first diagnosed during pregnancy in which the primary tumor was located in the liver. The ZES was well controlled with Zoton (Lansoprazole) following surgery. The patient had an uneventful pregnancy and delivery without significant complications.


CONCLUSIONS
The present case suggests that treatment with Zoton for ZES during pregnancy is safe and effective.
Mayer
Amit
A
Department of Obstetrics and Gynecology, Faculty of Health Sciences, Soroka University Medical Center, Ben Gurion University of the Negev, P.O. Box 151, Beer-Sheva 84101, Israel. amayer@bgumail.bgu.ac.il
Sheiner
Eyal
E
Holcberg
Gershon
G
D053799:2-Pyridinylmethylsulfinylbenzimidazoles / Q000627:therapeutic use*; D000328:Adult; D000897:Anti-Ulcer Agents / Q000627:therapeutic use*; D005260:Female; D015408:Gastrinoma / Q000150:complications* / Q000188:drug therapy / Q000473:pathology / Q000601:surgery; D005755:Gastrins / Q000097:blood; D006801:Humans; D007231:Infant, Newborn; D064747:Lansoprazole; D008297:Male; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000097:blood / Q000188:drug therapy* / Q000601:surgery; D011256:Pregnancy Outcome; D015043:Zollinger-Ellison Syndrome / Q000097:blood / Q000150:complications / Q000188:drug therapy* / Q000601:surgery
D053799:2-Pyridinylmethylsulfinylbenzimidazoles; D000897:Anti-Ulcer Agents; D005755:Gastrins; D064747:Lansoprazole