title: Ligand-based drug design methodologies in drug discovery process: an overview.
abstract: Ligand-based drug design represents an important research field in the drug discovery and optimisation process. This review provides an overview about the theoretical background of the quantitative structure activity relationship (QSAR) models.
authors.affiliation: Molecular Modeling Section, Dipartimento di Scienze Farmaceutiche, Università di Padova, Via Marzolo 5, I-35131 Padova, Italy.
authors.forename: Magdalena
authors.initials: M
authors.lastname: Bacilieri
authors.forename: Stefano
authors.initials: S
authors.lastname: Moro
mesh_terms: D015195:Drug Design; D008024:Ligands; D008962:Models, Theoretical; D015394:Molecular Structure; D004364:Pharmaceutical Preparations / Q000737:chemistry* / Q000378:metabolism; D021281:Quantitative Structure-Activity Relationship; D013678:Technology, Pharmaceutical / Q000379:methods
chemical_list: D008024:Ligands; D004364:Pharmaceutical Preparations