[The spectrum of vetebrates' cell lines sensitive to highly pathogenic influenza A/tern/SA/61 (H5N3) and A/duck/Novosibirsk/56/05 (H5N1) viruses].
The reproduction of highly pathogenic avian influenza (HPAI) A/tern/SA/61 H5N3 and A/ducklNovosibirsk/56/05 H5NI viruses was comparatively studied in 16 human and animal cell lines. The strain A/duck/Novosibirsk/56/05 was shown to have a wider range of hosts. The most sensitive transplanted cell lines were found to be feline fibroblasts (CC-81), primarily trypsin-treated cells of chick embryonic fibroblasts (CEF), the kidney of dogs (MDCK), pigs (SPEV), monkeys (Vero), the human conjunctiva (1-5C-4), and, to a lesser extent, the feline kidney (CRFK). Unlike the strain A/tern/South Africa/61, that A/duck/Novosibirsk/56105 replicated in the polecat brain cells (Mpf).
Deriabin
P  G
P
L'vov
D K
DK
Isaeva
E I
EI
Danlybaeva
G A
GA
Podcherniaeva
R Ia
RIa
Shchelkanov
M Iu
MIu
D000818:Animals; D002415:Cats; D002478:Cells, Cultured; D002642:Chick Embryo; D002522:Chlorocebus aethiops; D004285:Dogs; D006801:Humans; D053124:Influenza A Virus, H5N1 Subtype / Q000254:growth & development; D009980:Influenza A virus / Q000502:physiology*; D009976:Orthomyxoviridae Infections / Q000821:virology; D013045:Species Specificity; D013552:Swine; D014709:Vero Cells; D014776:Virus Cultivation; D014779:Virus Replication