title: Spinal cord stimulation: indications and outcomes.
abstract: Spinal cord stimulation (SCS) is the most commonly used implantable neurostimulation modality for management of pain syndromes. In this paper the authors describe the current indications for SCS and its efficacy in the treatment of those diseases. Specifically, the literature on patient selection and outcomes after SCS for failed-back surgery syndrome (FBSS), refractory angina pectoris, peripheral vascular disease, and complex regional pain syndrome (CRPS) Type I was reviewed. Effective pain relief was obtained in 60 to 80% of patients with FBSS and CRPS Type I. Furthermore, these patients had significant improvements in quality of life (QOL) and a significantly greater chance of returning to work than patients who did not undergo SCS. The use of SCS in patients with inoperable angina (that is, refractory angina pectoris) resulted in significant decreases in chest pain and hospital admissions as well as increased exercise duration, with less morbidity than with open procedures that were performed for pain control only. Patients with inoperable PVD also demonstrated significant improvements in pain relief, QOL, and limb mobility. Reported complications were mostly related to hardware and were relatively minor. Review of randomized controlled studies supports the use of SCS as an effective treatment modality for pain associated with FBSS, refractory angina pectoris, peripheral vascular disease, and CRPS Type I.
authors.affiliation: Department of Neurosurgery, Wayne State University, Detroit, Michigan, USA.
authors.forename: Anthony W
authors.initials: AW
authors.lastname: Lee
authors.forename: Julie G
authors.initials: JG
authors.lastname: Pilitsis
mesh_terms: D000698:Analgesia / Q000379:methods*; D000787:Angina Pectoris / Q000628:therapy; D001416:Back Pain / Q000601:surgery / Q000628:therapy; D002908:Chronic Disease; D002985:Clinical Protocols; D004599:Electric Stimulation Therapy / Q000009:adverse effects / Q000706:statistics & numerical data; D005121:Extremities / Q000098:blood supply; D005500:Follow-Up Studies; D006801:Humans; D007511:Ischemia / Q000628:therapy; D009369:Neoplasms / Q000150:complications; D059408:Pain Management; D018579:Patient Selection; D016491:Peripheral Vascular Diseases / Q000628:therapy; D011183:Postoperative Complications / Q000628:therapy; D011446:Prospective Studies; D011581:Psychological Tests; D016032:Randomized Controlled Trials as Topic; D012008:Recurrence; D012019:Reflex Sympathetic Dystrophy / Q000628:therapy; D012189:Retrospective Studies; D016896:Treatment Outcome