title: 16 Y chromosomal STR haplotypes in Japanese.
abstract: A total of 1079 Japanese males were typed for the following 16 Y chromosomal short tandem repeat (Y-STR) markers: DYS456, DYS389I, DYS390, DYS389II, DYS458, DYS19, DYS385, DYS393, DYS391, DYS439, DYS635, DYS392, Y GATA H4, DYS437, DYS438 and DYS448 using an AmpFlSTR(R) Yfiler PCR Amplification kit (Applied Biosystems). A total of 950 haplotypes for the 16 Y-STR markers were detected and, of these, 886 haplotypes were unique. The most frequent haplotype was found in 22 Japanese males. The haplotype diversity was 0.9992, indicating a high potential for differentiating between male individuals. There were 10 haplotypes with no allele detected at the DYS448 marker. Thus, the presence of such atypical haplotypes should be noted, when DNA typing results obtained from degraded DNA samples and/or DNA mixture samples from more than one male individual are being interpreted.
authors.affiliation: Fourth Biology Section, Department of First Forensic Science, National Research Institute of Police Science, 6-3-1, Kashiwanoha, Kashiwa, Chiba 277-0882, Japan. mizuno@nrips.go.jp
authors.forename: Natsuko
authors.initials: N
authors.lastname: Mizuno
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Nakahara
authors.forename: Kazumasa
authors.initials: K
authors.lastname: Sekiguchi
authors.forename: Kanako
authors.initials: K
authors.lastname: Yoshida
authors.forename: Minoru
authors.initials: M
authors.lastname: Nakano
authors.forename: Kentaro
authors.initials: K
authors.lastname: Kasai
mesh_terms: D044466:Asian People / Q000235:genetics; D041322:Chromosomes, Human, Y; D016172:DNA Fingerprinting; D005260:Female; D005819:Genetic Markers; D005828:Genetics, Population; D006239:Haplotypes; D006801:Humans; D007564:Japan; D008297:Male; D016133:Polymerase Chain Reaction; D020080:Tandem Repeat Sequences
chemical_list: D005819:Genetic Markers