title: Video documented follow-up of liver transplantation in Wilson's disease with predominant neurological manifestation.
abstract: Wilson's disease (WD) is a rare autosomal-recessive disorder of copper metabolism with predominantly hepatic and extrapyramidal motor symptoms. Copper chelating therapy has proven to be an effective treatment for WD. Yet, if conservative treatment fails, liver transplantation (LT) often is the only remaining therapeutic option. The indication for LT especially in patients with stable liver function but severe neurological manifestation is debated controversially. In this case report, we document the follow up of neurological symptoms in WD after LT for the first time on video.
authors.affiliation: Department of Neurology, Medizinische Hochschule Hannover, Hannover, Germany. thorsten.suess@web.de
authors.forename: Thorsten
authors.initials: T
authors.lastname: Suess
authors.forename: Martin
authors.initials: M
authors.lastname: Bokemeyer
authors.forename: Georg
authors.initials: G
authors.lastname: Schomerus
authors.forename: Frank
authors.initials: F
authors.lastname: Donnerstag
authors.forename: Michael Peter
authors.initials: MP
authors.lastname: Manns
authors.forename: Juergen
authors.initials: J
authors.lastname: Klempnauer
authors.forename: Hans
authors.initials: H
authors.lastname: Kolbe
authors.forename: Karin
authors.initials: K
authors.lastname: Weissenborn
mesh_terms: D000328:Adult; D005500:Follow-Up Studies; D006527:Hepatolenticular Degeneration / Q000473:pathology / Q000503:physiopathology* / Q000601:surgery*; D006801:Humans; D016031:Liver Transplantation / Q000379:methods*; D008297:Male; D009422:Nervous System Diseases / Q000503:physiopathology* / Q000628:therapy*; D013788:Thalamus / Q000473:pathology; D014741:Video Recording / Q000379:methods