title: Microbial enzymes involved in lactone compound metabolism and their biotechnological applications.
abstract: Lactone compounds are widely distributed in nature and play important roles in organisms. These compounds are synthesized and metabolized enzymatically in vivo; however, detailed investigation of these enzymes lags behind that of other common enzymes. In this paper, recent work on the enzymes involved in the metabolism of lactone compounds will be reviewed. In particular, fundamental and application studies on lactonases and Baeyer-Villiger monooxgenases of microbial origin are described.
authors.affiliation: Division of Applied Life Sciences, Graduate School of Agriculture, Kyoto University, Sakyo-ku, Kyoto, 606-8502, Japan.
authors.forename: Michihiko
authors.initials: M
authors.lastname: Kataoka
authors.forename: Kohsuke
authors.initials: K
authors.lastname: Honda
authors.forename: Keiji
authors.initials: K
authors.lastname: Sakamoto
authors.forename: Sakayu
authors.initials: S
authors.lastname: Shimizu
mesh_terms: D016954:Acinetobacter calcoaceticus / Q000201:enzymology*; D016960:Agrobacterium tumefaciens / Q000201:enzymology*; D001709:Biotechnology / Q000379:methods*; D005670:Fusarium / Q000201:enzymology*; D007783:Lactones / Q000378:metabolism*; D006899:Mixed Function Oxygenases / Q000378:metabolism*
chemical_list: D007783:Lactones; D006899:Mixed Function Oxygenases