title: Isolated intrasellar tuberculoma mimicking pituitary adenoma.
abstract: A 37-year-old woman presenting with galactorrhea and menstrual irregularity due to an intrasellar lesion of the pituitary gland underwent transsphenoidal surgery for histopathological diagnosis and removal of the lesion. Histological findings were consistent with a tuberculoma. The post-operative course was satisfactory with resolution of galactorrhea and improved ovulatory cycle. The patient was successfully treated with a combination of surgical resection and anti-tuberculous therapy for one year, which resulted in hormonal and tuberculosis control. This patient appears unique regarding the location of the lesion and the dramatic response to surgical treatment. Although differential diagnosis of inflammatory pathologies of the intrasellar region presents difficulties, this patient demonstrates that tuberculoma should be considered.
authors.affiliation: Department of Neurosurgery, School of Medicine, Uludag University, Gorukle Kampus, Bursa 16059, Turkey. selsus@uludag.edu.tr
authors.forename: Selcuk
authors.initials: S
authors.lastname: Yilmazlar
authors.forename: Ahmet
authors.initials: A
authors.lastname: Bekar
authors.forename: Ozgur
authors.initials: O
authors.lastname: Taskapilioglu
authors.forename: Sahsene
authors.initials: S
authors.lastname: Tolunay
mesh_terms: D000328:Adult; D000995:Antitubercular Agents / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D019635:Neurosurgical Procedures; D010911:Pituitary Neoplasms / Q000175:diagnosis* / Q000188:drug therapy / Q000503:physiopathology / Q000601:surgery; D012196:Review Literature as Topic; D014375:Tuberculoma / Q000150:complications* / Q000473:pathology
chemical_list: D000995:Antitubercular Agents