Hepatic and renal plasma cell lesions in a patient with multiple myeloma in hematological remission.
Plasma cell myeloma is characterized by plasma cell infiltrations, the presence of paraprotein and mostly skeletal destruction with osteolytic lesions. Liver or kidney infiltration has been described in patients with end stage multiple myeloma (MM), while the features of this malignant dissemination is not clearly understood. An atypical form of MM relapse is presented in a patient being in bone marrow remission, with simultaneous lesions in liver, kidney and suspicion of brain involvement. This case is an interesting model of refractory MM extraosseous involvement, that a clinician should be aware of when carrying out differential diagnosis.
Galani
Zacharoula
Z
First Department of Internal Medicine, National and Kapodistrian University of Athens, Laikon General Hospital, Athens, Greece.
Viniou
Nora
N
Kyrtsonis
Marie-Christine
MC
Sachanas
Sotirios
S
Antoniou
Telemachos
T
Dimopoulou
Maria N
MN
Vassilakopoulos
Theodoros P
TP
Korkolopoulou
Penelope
P
Nakopoulou
Lydia
L
Patsouris
Efstratios
E
Pangalis
Gerassimos A
GA
D001853:Bone Marrow / Q000187:drug effects / Q000473:pathology* / Q000528:radiation effects; D003937:Diagnosis, Differential; D006801:Humans; D007668:Kidney / Q000473:pathology*; D008099:Liver / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009101:Multiple Myeloma / Q000188:drug therapy / Q000473:pathology* / Q000532:radiotherapy; D010950:Plasma Cells / Q000187:drug effects / Q000473:pathology* / Q000528:radiation effects; D012074:Remission Induction