Treatment of delusions in dementia with Lewy bodies - response to pharmacotherapy.
BACKGROUND
Delusions are clinically important symptoms in dementia with Lewy bodies (DLB). The purpose of this review is to examine the level of evidence for treatment of delusions in DLB.


METHODS
To achieve this objective Medline was searched. Studies were included in the review if they were prospective, separated delusions from hallucinations and were tested in patients with DLB.


RESULTS
The review yielded a total of six studies. Although all studies showed effectiveness, only one study using rivastigmine had an adequate patient sample size and used a randomized controlled design.


CONCLUSIONS
Further studies are required before a definitive conclusion can be reached about effective treatments.
Fischer
Corinne
C
St. Michael's Hospital, Toronto, Ont., Canada. fischerc@smh.toronto.on.ca
Bozanovic
Radenka
R
Atkins
Jana H
JH
Rourke
Sean B
SB
D014150:Antipsychotic Agents / Q000627:therapeutic use*; D002800:Cholinesterase Inhibitors / Q000627:therapeutic use*; D003702:Delusions / Q000188:drug therapy* / Q000209:etiology; D006212:Hallucinations / Q000188:drug therapy; D006801:Humans; D020961:Lewy Body Disease / Q000150:complications / Q000188:drug therapy*; D011446:Prospective Studies; D016896:Treatment Outcome
D014150:Antipsychotic Agents; D002800:Cholinesterase Inhibitors