Almond shell xylo-oligosaccharides exhibiting immunostimulatory activity.
Partially O-acetylated xylo-oligosaccharides (DXO) isolated from almond shells by autohydrolysis as well as their de-acetylated form (DeXO) were subjected to chemical, molecular, and structural analyses. They represent a mixture of neutral and acidic oligomers and low-molecular weight polymers related to (4-O-methyl-D-glucurono)-D-xylan. DXO and DeXO showed direct mitogenic activity and enhancement of the T-mitogen-induced proliferation of rat thymocytes, indicating the immunostimulatory potential of the almond shell xylo-oligosaccharides.
Nabarlatz
Debora
D
Department of Chemical Engineering, ETSEQ, Rovira i Virgili University, Avinguda dels Països Catalans 26, E-43007 Tarragona, Catalunya, Spain. deboranabarlatz@gmail.com
Montané
Daniel
D
Kardosová
Alzbeta
A
Bekesová
Slávka
S
Hríbalová
Vera
V
Ebringerová
Anna
A
D000276:Adjuvants, Immunologic / Q000737:chemistry* / Q000494:pharmacology*; D009682:Magnetic Resonance Spectroscopy; D009844:Oligosaccharides / Q000737:chemistry* / Q000494:pharmacology*; D027861:Prunus / Q000737:chemistry* / Q000276:immunology; D017550:Spectroscopy, Fourier Transform Infrared; D014990:Xylans / Q000032:analysis; D014994:Xylose
D000276:Adjuvants, Immunologic; D009844:Oligosaccharides; D014990:Xylans; D014994:Xylose