title: Performance of laser bonded glass/polyimide microjoints in cerebrospinal fluid.
abstract: In this paper, laser bonded microjoints between glass and polyimide is considered to examine their potential applicability in encapsulating neural implants. To facilitate bonding between polyimide and glass, a thin titanium film with a thickness of 2 microm was deposited on borosilicate glass plates by a physical vapor deposition (PVD) process. Titanium coated glass was then joined with polyimide by using a cw fiber laser emitting at a wavelength of 1.1 microm (1.0 W) to prepare several tensile samples. Some of the samples were exposed to artificial cerebrospinal fluid (aCSF) at 37 degrees C for two weeks to assess long-term integrity of the joints. Both the as-received and aCSF soaked samples were subjected to uniaxial tensile loads for bond strengths measurements. The bond strengths for the as-received and aCSF soaked samples were measured to be 7.31 and 5.33 N/mm, respectively. Although the long-term exposure of the microjoints to aCSF has resulted in 26% reduction of bond strength, the samples still retain considerably high strength as compared with the titanium-polyimide samples. The failed glass/polyimide samples were also analyzed using optical microscopy, and failure mechanisms are discussed. In addition, a two dimensional finite element analysis (FEA) was conducted to understand the stress distribution within the substrate materials while the samples are in tension. The FEA results match reasonably well with the experimental load-displacement curves for as-received samples. Detailed discussion on various stress contours is presented in the paper, and the failure mechanisms observed from the experiment are shown in good agreement with the FEA predicted ones.
authors.affiliation: Department of Mechanical and Industrial Eng., Montana State University, Bozeman, MT 59717. amian@me.montana.edu
authors.forename: A
authors.initials: A
authors.lastname: Mian
authors.forename: G
authors.initials: G
authors.lastname: Newaz
authors.forename: D G
authors.initials: DG
authors.lastname: Georgiev
authors.forename: N
authors.initials: N
authors.lastname: Rahman
authors.forename: L
authors.initials: L
authors.lastname: Vendra
authors.forename: G
authors.initials: G
authors.lastname: Auner
authors.forename: R
authors.initials: R
authors.lastname: Witte
authors.forename: H
authors.initials: H
authors.lastname: Herfurth
mesh_terms: D001672:Biocompatible Materials; D001698:Biomedical Engineering; D002555:Cerebrospinal Fluid; D020342:Finite Element Analysis; D005898:Glass; D066298:In Vitro Techniques; D007834:Lasers; D008422:Materials Testing; D019635:Neurosurgical Procedures; D011108:Polymers; D019736:Prostheses and Implants; D013718:Tensile Strength; D014025:Titanium
chemical_list: D001672:Biocompatible Materials; D011108:Polymers; D014025:Titanium