title: Malignant peripheral nerve sheath tumour: an elusive diagnosis.
abstract: Malignant peripheral nerve sheath tumour (MPNST) also termed as spindle cell malignancy of the peripheral nerve Schwann cells or neurogenic sarcoma, represents approximately 10% of all soft tissue sarcomas. This tumour is usually found in the lower extremities and only 10-12% of all lesions occur in the head and neck region, which makes it a rare entity. The diagnosis of MPNST has been described as one of the most difficult and elusive diagnosis in the soft tissue diseases because of its non-specific presentation both clinically and histopathologically. This was overcome by the use of immunohistochemistry. A case of MPNST of the left maxillary antrum in a 45 -year -old male patient is reported.
authors.affiliation: Department of Oral Medicine and Radiology, JSS Dental College and Hospital, Mysore (Karnataka) - 570 015, India. patilkarthik@rediffmail.com
authors.forename: Karthikeya
authors.initials: K
authors.lastname: Patil
authors.forename: V G
authors.initials: VG
authors.lastname: Mahima
authors.forename: L
authors.initials: L
authors.lastname: Ambika
mesh_terms: D018959:CD57 Antigens / Q000032:analysis; D003937:Diagnosis, Differential; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008444:Maxillary Sinus Neoplasms / Q000473:pathology*; D008875:Middle Aged; D004676:Myelin Basic Protein / Q000032:analysis; D018317:Nerve Sheath Neoplasms / Q000473:pathology*; D009418:S100 Proteins / Q000032:analysis; D014746:Vimentin / Q000032:analysis
chemical_list: D018959:CD57 Antigens; D004676:Myelin Basic Protein; D009418:S100 Proteins; D014746:Vimentin