title: Retroperitoneal lymph node dissection in testicular cancer.
abstract: With long-term survival in excess of 90% across all stages, testicular cancer has come to represent the model for successful multidisciplinary cancer care. Retroperitoneal lymph node dissection (RPLND) remains an integral component of testis cancer management strategies for both early- and advanced-stage disease. Commensurate with improvements made in clinical staging and in our understanding of the natural history of testis cancer, lymphatic spread, and neuroanatomy, considerable modifications in the technique and template of RPLND have taken place. The morbidity of primary RPLND and postchemotherapy RPLND is low when performed by experienced surgeons. This article reviews the evolution, role, and technique of RPLND in contemporary practice.
authors.affiliation: Department of Urology, Indiana University, Indiana Cancer Pavilion, 535 N Barnhill Drive, Suite 420, Indianapolis, IN 46202, USA.
authors.forename: Niels-Erik B
authors.initials: NE
authors.lastname: Jacobsen
authors.forename: Richard S
authors.initials: RS
authors.lastname: Foster
authors.forename: John P
authors.initials: JP
authors.lastname: Donohue
mesh_terms: D014408:Biomarkers, Tumor / Q000097:blood; D004542:Ejaculation; D006801:Humans; D008197:Lymph Node Excision / Q000009:adverse effects / Q000379:methods*; D008297:Male; D009362:Neoplasm Metastasis; D009367:Neoplasm Staging; D009373:Neoplasms, Germ Cell and Embryonal / Q000473:pathology / Q000601:surgery*; D009919:Orchiectomy; D011182:Postoperative Care; D012187:Retroperitoneal Space; D013736:Testicular Neoplasms / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology / Q000601:surgery*; D000509:alpha-Fetoproteins / Q000032:analysis
chemical_list: D014408:Biomarkers, Tumor; D000509:alpha-Fetoproteins