title: Pregnancy on intensified hemodialysis: fetal surveillance and perinatal outcome.
abstract: OBJECTIVE
  To evaluate the effect of intensive fetal surveillance via Doppler ultrasound and fetal non-stress test on the perinatal outcome of pregnant women undergoing an intensified hemofiltration scheme.
  
  
  METHODS
  Five consecutive pregnancies of women undergoing intensified hemodialysis were analyzed due to the following parameters: maternal background, hemodialysis schedule during pregnancy, blood pressure, occurrence of fetal complications, occurrence of obstetric complications, gestational week at delivery, mode of delivery, and newborn outcome and follow-up.
  
  
  RESULTS
  All pregnancies resulted in a live birth, mean gestational age was 32 weeks. Intrauterine growth restriction occurred in 4 fetuses, pathological umbilical artery flow velocity waveforms in 2. The mean birth weight was 1,764 g (range 1,274-2,465 g). Cesarean section was performed in 3 patients because of fetal distress. None of the patients developed severe complications like pre-eclampsia.
  
  
  CONCLUSIONS
  Although intensified dialysis enables the maintenance of stable uteroplacental and fetal perfusion, intensive fetal monitoring is mandatory to reduce perinatal morbidity and mortality in pregnant women on maintenance dialysis.
authors.affiliation: Department of Obstetrics and Gynecology, Charité University Hospital, Campus Mitte, Berlin, Germany.
authors.forename: Christian
authors.initials: C
authors.lastname: Bamberg
authors.forename: Fritz
authors.initials: F
authors.lastname: Diekmann
authors.forename: Michael
authors.initials: M
authors.lastname: Haase
authors.forename: Klemens
authors.initials: K
authors.lastname: Budde
authors.forename: Berthold
authors.initials: B
authors.lastname: Hocher
authors.forename: Horst
authors.initials: H
authors.lastname: Halle
authors.forename: John
authors.initials: J
authors.lastname: Hartung
mesh_terms: D000328:Adult; D001724:Birth Weight; D001783:Blood Flow Velocity; D015148:Cardiotocography; D002675:Child, Preschool; D005260:Female; D005316:Fetal Distress / Q000209:etiology; D005317:Fetal Growth Retardation / Q000209:etiology; D005500:Follow-Up Studies; D005865:Gestational Age; D006801:Humans; D007223:Infant; D007676:Kidney Failure, Chronic / Q000503:physiopathology / Q000628:therapy*; D017078:Laser-Doppler Flowmetry; D050498:Live Birth; D021041:Placental Circulation; D006831:Polyhydramnios / Q000209:etiology; D011247:Pregnancy; D011248:Pregnancy Complications / Q000503:physiopathology / Q000628:therapy*; D011295:Prenatal Care / Q000379:methods*; D006435:Renal Dialysis / Q000009:adverse effects*; D012189:Retrospective Studies; D013997:Time Factors; D016216:Ultrasonography, Prenatal