Dietary agents/supplements hit the clinic for prostate cancer chemoprevention.
Dietary studies of men throughout the world have identified certain foods/food-derived substances that are correlated to prostate cancer risk. While radical modification of cultural dietary habits with the goal of preventing prostate cancer remains challenging, supplementation with certain foods and/or food-derived substances identified as having potential chemopreventative properties may be a feasible approach, particularly for Western cultures. Before such chemopreventative strategies can be recommended to patients, their benefits must be rigorously demonstrated in appropriately designed clinical trials. This paper discusses several agents currently under scientific scrutiny for prostate cancer chemopreventative activities and the data available, thus far.
Bemis
Debra L
DL
Department of Urology, Columbia University Medical Center, New York, NY 10032, USA. dlb2004@columbia.edu
Buttyan
Ralph
R
D018890:Chemoprevention / Q000379:methods*; D002986:Clinical Trials as Topic; D019587:Dietary Supplements; D006801:Humans; D008297:Male; D011471:Prostatic Neoplasms / Q000517:prevention & control*