Calyciphylline D, a novel alkaloid with an unprecedented fused-pentacyclic skeleton from Daphniphyllum calycinum.
[structure: see text]. Calyciphylline D (1), a novel Daphniphyllum alkaloid with an unprecedented fused-pentacyclic skeleton containing a 8-azatricyclo[4.2.1.0.4,8]nonane ring system, has been isolated from the leaves of Daphniphyllum calycinum (Daphniphyllaceae), and the structure and relative stereochemistry were elucidated on the basis of spectroscopic data.
Saito
Shizuka
S
Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan.
Kubota
Takaaki
T
Fukushi
Eri
E
Kawabata
Jun
J
Zhang
Huiping
H
Kobayashi
Jun'ichi
J
D000470:Alkaloids / Q000737:chemistry / Q000302:isolation & purification*; D001372:Aza Compounds / Q000737:chemistry*; D006576:Heterocyclic Compounds, 4 or More Rings / Q000737:chemistry / Q000302:isolation & purification*; D009682:Magnetic Resonance Spectroscopy; D008958:Models, Molecular; D015394:Molecular Structure; D018515:Plant Leaves / Q000737:chemistry; D011083:Polycyclic Compounds / Q000737:chemistry / Q000302:isolation & purification*; D031995:Saxifragaceae / Q000737:chemistry*; D013237:Stereoisomerism
D000470:Alkaloids; D001372:Aza Compounds; D006576:Heterocyclic Compounds, 4 or More Rings; D011083:Polycyclic Compounds; C519467:calyciphylline D