[Classification signs of end-stage pigmented retinitis].
Identification of objective criteria for early-stage pigmented retinitis (PR) remains urgent today. Visual system changes reflecting retinal metabolic and structural disturbances (a change in the time and amplitude parameters of ERG, an increase in dark adaptation, changes in the color palette and the thickness of layers of photoreceptors and pigment epithelium of the retina on the OST scans) were detected in 31% of the examined relatives of patients with PR. The authors show the diagnostic value of retinal optic coherent tomography in the diagnosis of PR and the expediency of its use for objective estimation of retinal structural changes along with functional studies. The statistical studies including descriptive, regression, and discriminant analyses have provided evidence that the characteristics of the visual system in patients with end-stage PR differ from those in the controls. Studies that can determine differences in the state of the visual system of the groups under study and significantly discriminate persons with the normally functioning visual system from patients with PR have been identified.
Zhukova
S I
SI
Shchuko
A G
AG
Malyshev
V V
VV
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D003937:Diagnosis, Differential; D018450:Disease Progression; D004596:Electroretinography; D006801:Humans; D008266:Macula Lutea / Q000000981:diagnostic imaging / Q000473:pathology / Q000503:physiopathology; D033401:Microscopy, Acoustic; D009887:Ophthalmoscopy; D012174:Retinitis Pigmentosa / Q000145:classification* / Q000175:diagnosis*; D012720:Severity of Illness Index; D041623:Tomography, Optical Coherence