title: A case of naturally acquired inhalation anthrax: clinical care and analyses of anti-protective antigen immunoglobulin G and lethal factor.
abstract: This report describes the first case of naturally acquired inhalation anthrax in the United States since 1976. The patient's clinical course included adjunctive treatment with human anthrax immunoglobulin. Clinical correlation of serologic assays for the lethal factor component of lethal toxin and anti-protective antigen immunoglobulin G are also presented.
authors.affiliation: Section of Pulmonary and Critical Care Medicine, Guthrie Clinic, Sayre, PA, USA.
authors.forename: James J
authors.initials: JJ
authors.lastname: Walsh
authors.forename: Nicki
authors.initials: N
authors.lastname: Pesik
authors.forename: Conrad P
authors.initials: CP
authors.lastname: Quinn
authors.forename: Veronica
authors.initials: V
authors.lastname: Urdaneta
authors.forename: Clare A
authors.initials: CA
authors.lastname: Dykewicz
authors.forename: Anne E
authors.initials: AE
authors.lastname: Boyer
authors.forename: Jeannette
authors.initials: J
authors.lastname: Guarner
authors.forename: Patricia
authors.initials: P
authors.lastname: Wilkins
authors.forename: Kim J
authors.initials: KJ
authors.lastname: Norville
authors.forename: John R
authors.initials: JR
authors.lastname: Barr
authors.forename: Sherif R
authors.initials: SR
authors.lastname: Zaki
authors.forename: Jean B
authors.initials: JB
authors.lastname: Patel
authors.forename: Sarah P
authors.initials: SP
authors.lastname: Reagan
authors.forename: James L
authors.initials: JL
authors.lastname: Pirkle
authors.forename: Tracee A
authors.initials: TA
authors.lastname: Treadwell
authors.forename: Nancy Rosenstein
authors.initials: NR
authors.lastname: Messonnier
authors.forename: Lisa D
authors.initials: LD
authors.lastname: Rotz
authors.forename: Richard F
authors.initials: RF
authors.lastname: Meyer
authors.forename: David S
authors.initials: DS
authors.lastname: Stephens
mesh_terms: D000328:Adult; D000881:Anthrax / Q000175:diagnosis* / Q000628:therapy*; D022122:Anthrax Vaccines / Q000008:administration & dosage* / Q000276:immunology; D000942:Antigens, Bacterial / Q000276:immunology*; D001408:Bacillus anthracis / Q000302:isolation & purification; D001774:Blood Chemical Analysis; D004781:Environmental Exposure / Q000009:adverse effects; D004797:Enzyme-Linked Immunosorbent Assay; D005098:Exotoxins / Q000097:blood; D005500:Follow-Up Studies; D006801:Humans; D007074:Immunoglobulin G / Q000276:immunology* / Q000378:metabolism; D001239:Inhalation; D008297:Male; D018570:Risk Assessment; D012720:Severity of Illness Index; D014195:Travel; D014481:United States
chemical_list: D022122:Anthrax Vaccines; D000942:Antigens, Bacterial; D005098:Exotoxins; D007074:Immunoglobulin G