title: Spontaneous splenic rupture in primary cytomegalovirus infection.
abstract: BACKGROUND
  Spontaneous splenic rupture is a rare occurrence in primary cytomegalovirus infection.
  
  
  METHODS
  We report two cases of spontaneous rupture of the spleen associated with primary cytomegalovirus infection in young immunocompetent adults. One patient had iron deficiency anemia, and the other a pyruvate kinase deficiency. Nonoperative management was successful in both cases.
  
  
  CONCLUSIONS
  Nine other cases identified by a search of the medical literature are also reviewed. These cases do not show evidence of any particular risk factor.
authors.affiliation: Department of internal medicine, Hôpital Nord, Saint-Etienne, Cedex.
authors.forename: Nicolas
authors.initials: N
authors.lastname: Maillard
authors.forename: Martial
authors.initials: M
authors.lastname: Koenig
authors.forename: Sylvie
authors.initials: S
authors.lastname: Pillet
authors.forename: Muriel
authors.initials: M
authors.lastname: Cuilleron
authors.forename: Pascal
authors.initials: P
authors.lastname: Cathébras
mesh_terms: D000328:Adult; D003586:Cytomegalovirus Infections / Q000150:complications*; D005260:Female; D006801:Humans; D008297:Male; D012422:Rupture, Spontaneous; D013158:Splenic Diseases / Q000821:virology*; D013163:Splenomegaly / Q000821:virology; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome