[Cytogenetic impacts of air-argon environment on epitheliocytes of the mice cornea].
The purpose was to look into the effects of 24-hr. exposure in a normoxic air-argon environment (AAE) on the epitheliocyte proliferative system, i.e. chromosomal aberrations dynamics and cornea proliferative activity, in laboratory mice. Argon was found to significantly decrease the percentage of spontaneous mutations in cells and, probably, to induce reversible inhibition of cell division. Subsequent experiments may not only disclose the still unknown properties and advantages of argon but also shed light on cell mechanisms triggered by the noble gases in general.
Kussmaul'
A R
AR
Bogacheva
M A
MA
Shkurat
T P
TP
Pavlov
N B
NB
D000388:Air; D000818:Animals; D016587:Antimutagenic Agents / Q000494:pharmacology; D001128:Argon; D002465:Cell Movement / Q000502:physiology; D002869:Chromosome Aberrations; D003315:Cornea / Q000166:cytology* / Q000473:pathology; D003582:Cytogenetics / Q000379:methods*; D004777:Environment; D015622:Epithelioid Cells / Q000166:cytology*; D000860:Hypoxia / Q000473:pathology; D008297:Male; D051379:Mice; D008938:Mitosis / Q000187:drug effects; D013692:Telophase / Q000235:genetics*; D013997:Time Factors
D016587:Antimutagenic Agents; D001128:Argon