title: Obsessive-compulsive disorder in youth with and without a chronic tic disorder.
abstract: The goal of this study was to discriminate subtypes of pediatric obsessive-compulsive disorder (OCD) among youth with and without a comorbid tic disorder. Seventy-four youth (M(age)=9.7+/-2.3 years) with a principal diagnosis of OCD, with (n=46) or without (n=28) a comorbid tic disorder, were assessed with a semi-structured diagnostic interview and the Children's Yale Brown Obsessive-Compulsive Scale (CY-BOCS). The CY-BOCS Symptom Checklist was used to categorize obsessions and compulsions. Group differences were analyzed by t tests, chi(2), and discriminant function analyses. Results suggested that subjects without tics had significantly more contamination obsessions, sexual obsessions, and counting compulsions than youth with comorbid tics. Generally speaking, however, youth with and without tics had similar symptom presentations. These data suggest that pediatric OCD patients with and without comorbid tics may have some aspects of symptom presentation that differ, but generally have more OCD symptoms in common than different. Implications of these findings on clinical presentation and treatment efficacy are highlighted.
authors.affiliation: Department of Psychiatry, University of Florida, Gainesville, Florida 32610, USA. estorch@health.usf.edu
authors.forename: Eric A
authors.initials: EA
authors.lastname: Storch
authors.forename: David
authors.initials: D
authors.lastname: Stigge-Kaufman
authors.forename: Wendi E
authors.initials: WE
authors.lastname: Marien
authors.forename: Muhammad
authors.initials: M
authors.lastname: Sajid
authors.forename: Marni L
authors.initials: ML
authors.lastname: Jacob
authors.forename: Gary R
authors.initials: GR
authors.lastname: Geffken
authors.forename: Wayne K
authors.initials: WK
authors.lastname: Goodman
authors.forename: Tanya K
authors.initials: TK
authors.lastname: Murphy
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D002908:Chronic Disease; D005260:Female; D006801:Humans; D008297:Male; D009771:Obsessive-Compulsive Disorder / Q000175:diagnosis* / Q000453:epidemiology* / Q000523:psychology; D012720:Severity of Illness Index; D011795:Surveys and Questionnaires; D013981:Tic Disorders / Q000175:diagnosis / Q000453:epidemiology*