Leukocytospermia: relationship to sperm deoxyribonucleic acid integrity in patients evaluated for male factor infertility.
The purpose of our study was to analyze the relationship of leukocytospermia to sperm DNA damage as assessed by the DNA integrity assay. Results indicate that leukocytospermia has a significant negative effect on the standard semen parameters of concentration, motility, and morphology but at most a very weak effect on DNA integrity as measured by the DNA fragmentation assay.
Moskovtsev
Sergey I
SI
Andrology Laboratory, Department of Pathology and Laboratory Medicine, Mount Sinai Hospital, Toronto, Ontario, Canada.
Willis
Jennifer
J
White
John
J
Mullen
J Brendan M
JB
D000328:Adult; D004247:DNA / Q000235:genetics*; D006801:Humans; D007248:Infertility, Male / Q000235:genetics* / Q000473:pathology / Q000503:physiopathology; D007958:Leukocyte Count; D007962:Leukocytes / Q000473:pathology*; D008297:Male; D013094:Spermatozoa / Q000473:pathology / Q000502:physiology*
D004247:DNA