title: [Dengue: sero-epidemiological survey and virological surveillance in Campinas, São Paulo, Brazil].
abstract: The epidemiology of dengue in the municipality of Campinas, São Paulo, Brazil, was studied in 1998 using a randomized sero-epidemiological survey. Epidemiological surveillance data from 1996-2003 were also analyzed, with an emphasis on virological surveillance. 1,260 individuals participated in the survey and had blood samples drawn by finger stick on filter paper. Blood samples were tested by EIA-ICC, an enzyme immunoassay using infected cells as antigen. Dengue antibody prevalence (14.79%) was lower than in other surveys in other States of Brazil, but higher than in two other serological surveys in São Paulo State. Dengue antibody prevalence was far higher than the reported case incidence during the 1996, 1997, and 1998 epidemics. Antibody prevalence and reported case incidence in different health districts were disproportional. The article concludes by recommending further research on the significance of transmission rates during epidemics and more intensive virological surveillance, especially in years with few reported cases.
authors.affiliation: Superintendencia de Controle de Endemias, Rua Sao Carlos 546, Campinas, SP 13035-420, Brazil. virgilia@sucen.sp.gov.br
authors.forename: Virgília Luna Castor de
authors.initials: VL
authors.lastname: Lima
authors.forename: Osias
authors.initials: O
authors.lastname: Rangel
authors.forename: Valmir Roberto
authors.initials: VR
authors.lastname: Andrade
authors.forename: Naoko Yanagizawa Jardim da
authors.initials: NY
authors.lastname: Silveira
authors.forename: Susely Salviano de
authors.initials: SS
authors.lastname: Oliveira
authors.forename: Luiz Tadeu M
authors.initials: LT
authors.lastname: Figueiredo
mesh_terms: D000293:Adolescent; D000328:Adult; D000914:Antibodies, Viral / Q000097:blood*; D001938:Brazil / Q000453:epidemiology; D002648:Child; D002675:Child, Preschool; D003715:Dengue / Q000097:blood / Q000453:epidemiology* / Q000276:immunology / Q000635:transmission; D003716:Dengue Virus / Q000276:immunology* / Q000302:isolation & purification; D018563:Disease Notification; D004196:Disease Outbreaks; D005260:Female; D006801:Humans; D007124:Immunoenzyme Techniques; D007074:Immunoglobulin G / Q000097:blood / Q000276:immunology; D015994:Incidence; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008875:Middle Aged; D011159:Population Surveillance; D015995:Prevalence; D016036:Seroepidemiologic Studies; D014504:Urban Health
chemical_list: D000914:Antibodies, Viral; D007074:Immunoglobulin G