title: An approach to the antiinflammatory activity of borjatriol.
abstract: The antiinflammatory activity of borjatriol (a diterpenoid isolated from SIDERITIS MUGRONENSIS Borja) was tested using the cotton pellet-granuloma assay. The compound inhibited the granuloma weight and the serum lysozyme activity in a dose-dependently way. The determination of this enzyme has allowed us to distinguish between an irritant (carrageenan) which reduces the granuloma weight and antiinflammatory substances (phenylbutazone and borjatriol).
authors.affiliation: Departamento de Farmacognosia y Farmacodinamia, Facultad de Farmacia, Valencia, Spain.
authors.forename: A
authors.initials: A
authors.lastname: Villar
authors.forename: R
authors.initials: R
authors.lastname: Salom
authors.forename: M J
authors.initials: MJ
authors.lastname: Alcaraz