title: Chemoprofile and bioactivities of Taverniera cuneifolia (Roth) Arn.: a wild relative and possible substitute of Glycyrrhiza glabra L.
abstract: Chemoprofile of Taverniera cuneifolia (Roth) Arn. a wild relative of commercial licorice (Glycyrrhiza glabra L) is presented. Both T. cuneifolia and G. glabra L were found to be very similar phytochemically. At least eighteen chromatophores were found similar in both the plants including the sweetening principle, glycyrrhizin. The extracts of T. cuneifolia root, exhibited promising anti-inflammatory, anti-tumor, anti germ tube formation (in Candida albicans), protection from mutagen toxicity and cytotoxic activities comparable to that of G. glabra. In general, the results suggest that T. cuneifolia could be used as substitute of G. glabra.
authors.affiliation: School of Life Sciences, SRTM University, Nanded, Maharashtra, India.
authors.forename: Gajanan B
authors.initials: GB
authors.lastname: Zore
authors.forename: Umakanth B
authors.initials: UB
authors.lastname: Winston
authors.forename: Babasaheb S
authors.initials: BS
authors.lastname: Surwase
authors.forename: Nisha S
authors.initials: NS
authors.lastname: Meshram
authors.forename: V D
authors.initials: VD
authors.lastname: Sangle
authors.forename: Smita S
authors.initials: SS
authors.lastname: Kulkarni
authors.forename: S
authors.initials: S
authors.lastname: Mohan Karuppayil
mesh_terms: D000818:Animals; D019380:Anti-HIV Agents / Q000032:analysis*; D000893:Anti-Inflammatory Agents / Q000032:analysis*; D000935:Antifungal Agents / Q000032:analysis; D016587:Antimutagenic Agents / Q000032:analysis; D000970:Antineoplastic Agents / Q000032:analysis; D002176:Candida albicans; D006035:Glycyrrhiza / Q000737:chemistry*; D010936:Plant Extracts / Q000737:chemistry*; D018517:Plant Roots / Q000737:chemistry*; D051381:Rats; D017208:Rats, Wistar; D012486:Salmonella typhimurium
chemical_list: D019380:Anti-HIV Agents; D000893:Anti-Inflammatory Agents; D000935:Antifungal Agents; D016587:Antimutagenic Agents; D000970:Antineoplastic Agents; D010936:Plant Extracts