Strategies for the development of the urinary catheter.
Indwelling urinary catheters are utilized in the management of a wide range of conditions both in an acute and a chronic setting. However, utilization of this type of device is associated with a number of issues, including an increased propensity to develop bacteriuria, symptomatic infection and also encrusted deposits on the device. The development of novel biomaterials, incorporation of therapeutic agents and other strategies to minimize the issues associated with these devices are discussed in this review.
Hamill
Turlough M
TM
School of Pharmacy, Queens University Belfast, Medical Biology Centre, 97 Lisburn Road, Belfast, UK. thamill01@qub.ac.uk
Gilmore
Brendan F
BF
Jones
David S
DS
Gorman
Sean P
SP
D001424:Bacterial Infections / Q000209:etiology / Q000517:prevention & control*; D002408:Catheters, Indwelling / Q000009:adverse effects*; D004867:Equipment Design; D019544:Equipment Failure Analysis; D006801:Humans; D016459:Prosthesis-Related Infections / Q000209:etiology / Q000517:prevention & control*; D014546:Urinary Catheterization / Q000009:adverse effects* / Q000295:instrumentation* / Q000379:methods; D014552:Urinary Tract Infections / Q000209:etiology / Q000517:prevention & control*