title: Regioselective ring-opening metathesis-cross metathesis of bridgehead-substituted 7-azanorbornene.
abstract: [structure: see text]. In this paper we describe a highly regioselective ring-opening metathesis-cross metathesis (ROM-CM) process between methyl N-Boc-7-azabicyclo[2.2.1]hept-2-en-1-carboxylate, a bridgehead-substituted 7-azanorbornene system, and electron-poor olefins. The reaction opens the way to the synthesis of interesting alpha-amino diacids and pyrrolizinone derivatives that incorporate quaternary stereocenters.
authors.affiliation: Departamento de Química, Universidad de La Rioja, Grupo de Síntesis Química de La Rioja, UA-CSIC, 26006 Logroño, Spain.
authors.forename: J
authors.initials: J
authors.lastname: Carreras
authors.forename: A
authors.initials: A
authors.lastname: Avenoza
authors.forename: J H
authors.initials: JH
authors.lastname: Busto
authors.forename: J M
authors.initials: JM
authors.lastname: Peregrina