[The frequency of the occurrence of genes ermA, ermB, ermC and msrA/B among methicillin-resistant Staphylococcus aureus strains resistant to erythromycin].
The group of 50 clinical MRSA strains resistant to MLS-B was examined for the presence of ermA, ermB, ermC, msrA/B genes by using PCR. Gene ermA was found in 43 strains (86%). 20 of ermA strains demonstrated inducible whereas 23 constitutive type of expression. The gene ermC was present in 15 of examined MRSA strains (30%). The expression of the gene was inducible in the case of 9 and constitutive in the case of 6 of the strains. The msrA/B gene was present in the case of 5 strains (10%). The ermB gene was not detected among the investigated strains.
Młynarczyk
Grazyna
G
Katedra i Zakład Mikrobiologii Lekarskiej AM w Warszawie.
Młynarczyk
Andrzej
A
Szymanek
Ksenia
K
Luczak
Mirosław
M
D001426:Bacterial Proteins / Q000302:isolation & purification*; D024901:Drug Resistance, Multiple, Bacterial / Q000235:genetics; D005798:Genes, Bacterial; D006801:Humans; D008565:Membrane Proteins / Q000302:isolation & purification*; D016106:Methicillin Resistance / Q000235:genetics*; D008780:Methyltransferases / Q000302:isolation & purification*; D008826:Microbial Sensitivity Tests; D011044:Poland; D016133:Polymerase Chain Reaction; D011815:R Factors / Q000378:metabolism; D013045:Species Specificity; D013211:Staphylococcus aureus / Q000145:classification* / Q000235:genetics*
D001426:Bacterial Proteins; D008565:Membrane Proteins; C477297:MsrR protein, Staphylococcus aureus; D008780:Methyltransferases; C431709:ErmA protein, Bacteria