Nucleo-copolymers: oligonucleotide-based amphiphilic diblock copolymers.
For the first time, poly(butadiene) has been covalently linked to an oligonucleotide sequence and the resulting nucleo-copolymer exhibits amphiphilic properties in dilute aqueous solution, self-assembling into nanometer-sized vesicular structures.
Teixeira
Francisco
F
Departement Chemie, Universität Basel, Klingelbergstrasse 80, CH-4056 Basel, Switzerland.
Rigler
Per
P
Vebert-Nardin
Corinne
C
D002070:Butadienes / Q000138:chemical synthesis / Q000737:chemistry*; D003432:Cross-Linking Reagents / Q000737:chemistry; D020724:Elastomers / Q000138:chemical synthesis / Q000737:chemistry*; D018613:Microscopy, Confocal; D017348:Microscopy, Electron, Scanning Transmission; D009841:Oligonucleotides / Q000138:chemical synthesis / Q000737:chemistry*; D011066:Poly C / Q000138:chemical synthesis / Q000737:chemistry*; D011108:Polymers / Q000138:chemical synthesis / Q000737:chemistry*; D017550:Spectroscopy, Fourier Transform Infrared
D002070:Butadienes; D003432:Cross-Linking Reagents; D020724:Elastomers; D009841:Oligonucleotides; D011108:Polymers; D011066:Poly C; C028834:polybutadiene