[Cure effects of Jiangu Fufang on osteoporotic model induced by ovariectomy].
OBJECTIVE
To explore the cure effects of Jiangu Fufang on osteoporotic model induced by ovariectomy.


METHODS
Rats were ovariectomized and administered drugs for 3 monthes. Bone mineral density and biomechanics properties, histomorphometric analysis and biochemical index such as calcium, phosphorus, alkaline phosphatase were detected.


RESULTS
Jiangu Fufang could significantly increase bone density and biomechanics properties. The level of calcium, phosphorus and alkaline phosphatase were restored by Jiangu Fufang. Jiangu Fufang could significantly increase area of bone trabecula, thickness of cortical bone and bone trabecula.


CONCLUSIONS
Jiangu Fufang could cure osteoporosis through increasing bone mineral density, improving bone biomechanics properties, and effecting bone metabolism.
Deng
Ying-Xian
YX
The General Hospital, the Air Force of the Chinese People's Liberation Army, Beijing 100036, China.
Ma
Zeng-Chun
ZC
Tan
Hong-Ling
HL
Xiao
Cheng-Rong
CR
Wang
Yu-Guang
YG
Gao
Yue
Y
D000469:Alkaline Phosphatase / Q000097:blood; D000818:Animals; D001696:Biomechanical Phenomena; D015519:Bone Density / Q000187:drug effects*; D002118:Calcium / Q000097:blood; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification / Q000494:pharmacology* / Q000627:therapeutic use; D005260:Female; D005269:Femur / Q000503:physiopathology; D008159:Lumbar Vertebrae / Q000187:drug effects / Q000473:pathology / Q000503:physiopathology; D010024:Osteoporosis / Q000097:blood / Q000188:drug therapy* / Q000503:physiopathology; D010052:Ovariectomy; D010758:Phosphorus / Q000097:blood; D008517:Phytotherapy; D010946:Plants, Medicinal / Q000737:chemistry*; D011897:Random Allocation; D051381:Rats; D017207:Rats, Sprague-Dawley
D004338:Drug Combinations; D004365:Drugs, Chinese Herbal; C528308:jiangu fufang; D010758:Phosphorus; D000469:Alkaline Phosphatase; D002118:Calcium