Hypertrophic osteopathy associated with disseminated metastases of renal cell carcinoma in the dog: a case report.
A 6-year-old, mixed breed, intact male dog showed signs of left carpal joint swelling and weakness of the forelimbs one month before presentation. The symptoms gradually progressed to bilateral carpal and tarsal joint swelling and tetraparalysis. There were a number of radiographically identified lytic-proliferative bone lesions noted on the axial skeleton. Hypertrophic osteopathy of the metacarpi and all distal long bones was also evident. Because of the deteriorating quality of life and guarded prognosis, the patient was euthanized and a complete necropsy was performed. Renal cell carcinoma, with metastasis to the lung, thoracic vertebrae, ribs, and the right adrenal gland, was diagnosed. To our knowledge, renal cell carcinoma with bone metastases and hypertrophic osteopathy has not been reported in dogs.
Chiang
Yu-Ching
YC
Department of Veterinary Medicine, College of Bio-Resource and Agriculture, National Taiwan University, Taipei, Taiwan, ROC.
Liu
Chen-Hsuan
CH
Ho
Sheng-Yu
SY
Lin
Chung-Tien
CT
Yeh
Lih-Seng
LS
D000818:Animals; D001859:Bone Neoplasms / Q000556:secondary / Q000662:veterinary*; D002292:Carcinoma, Renal Cell / Q000556:secondary / Q000662:veterinary*; D004283:Dog Diseases / Q000473:pathology*; D004285:Dogs; D017809:Fatal Outcome; D007680:Kidney Neoplasms / Q000473:pathology / Q000662:veterinary*; D008297:Male