title: [Studies on using spray drying technique in preparing Ophiopogon japonicus saponin enteric microsphere by orthogonal experimental design].
abstract: OBJECTIVE
  To explore the best technique parameters on preparing ophiopogon japonicus saponin enteric microsphere by spray drying technique.
  
  
  METHODS
  The best technique parameters were investigated by orthogonal experimental design and by the target, such as surface appearances, encapsulated efficiency, etc.
  
  
  RESULTS
  The best technique parameters included the inlet temperature (90 degrees C ), the feeding speed (10 mL x min(- 1)), and the rotate speed of atomizer (50 r x min(-1)).
  
  
  CONCLUSIONS
  Ophiopogon japonicus saponin enteric microsphere accorded with the expecting demand. The main influencing factor was inlet temperature . It is suitable to industrialize in preparing Traditional Chinese Medicine microsphere.
authors.affiliation: Shanghai University of traditional Chinese medicine, Shanghai 201203, China.
authors.forename: Lan
authors.initials: L
authors.lastname: Shen
authors.forename: Yi
authors.initials: Y
authors.lastname: Feng
authors.forename: De-sheng
authors.initials: DS
authors.lastname: Xu
authors.forename: Xiao
authors.initials: X
authors.lastname: Lin
mesh_terms: D004339:Drug Compounding / Q000379:methods*; D008854:Microscopy, Electron; D008863:Microspheres; D031441:Ophiopogon / Q000737:chemistry*; D010946:Plants, Medicinal / Q000737:chemistry; D012503:Saponins / Q000737:chemistry / Q000302:isolation & purification*; D013608:Tablets, Enteric-Coated / Q000737:chemistry; D013696:Temperature
chemical_list: D012503:Saponins; D013608:Tablets, Enteric-Coated