title: Nuclear architecture--an island no more.
abstract: The eukaryotic nucleus has been the neglected child of cell biology. The "International Symposium on Functional Organization of the Nucleus" held in January on Awaji Island, Japan, highlighted recent work on nuclear organization and function. Emerging from this conference was a holistic view in which diverse chemical and physical signals link the nuclear and cytoplasmic compartments of cells.
authors.affiliation: Lawrence Berkeley National Laboratory and University of California, Berkeley, Berkeley, CA 94720, USA. afdernburg@lbl.gov
authors.forename: Abby F
authors.initials: AF
authors.lastname: Dernburg
authors.forename: Tom
authors.initials: T
authors.lastname: Misteli
mesh_terms: D021581:Active Transport, Cell Nucleus / Q000502:physiology; D000818:Animals; D002451:Cell Compartmentation / Q000502:physiology; D002454:Cell Differentiation / Q000235:genetics; D019070:Cell Lineage / Q000235:genetics; D022003:Cell Nucleus Structures / Q000235:genetics / Q000378:metabolism* / Q000648:ultrastructure*; D002843:Chromatin / Q000235:genetics / Q000378:metabolism* / Q000648:ultrastructure*; D016678:Genome / Q000235:genetics; D006801:Humans; D009154:Mutation / Q000235:genetics; D009687:Nuclear Proteins / Q000235:genetics / Q000378:metabolism*
chemical_list: D002843:Chromatin; D009687:Nuclear Proteins