Neuropathology for the neuroradiologist: fluorescence in situ hybridization.
Fluorescence in situ hybridization is a molecular cytogenetic technique that localizes segments of DNA within tumor cells by using dyes that are visible with a fluorescent microscope. The technique has proved useful in typing a variety of tumors such as oligodendrogliomas and in understanding the genetic forces driving oncogenesis.
Wippold
F J
FJ
Neuroradiology Section, Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO 63110, USA. wippoldf@wustl.edu
Perry
A
A
D005820:Genetic Testing; D006801:Humans; D017404:In Situ Hybridization, Fluorescence / Q000379:methods*; D009423:Nervous System Neoplasms / Q000175:diagnosis* / Q000235:genetics*; D009485:Neuroradiography