TNM classification system for primary cutaneous lymphomas other than mycosis fungoides and Sezary syndrome: a proposal of the International Society for Cutaneous Lymphomas (ISCL) and the Cutaneous Lymphoma Task Force of the European Organization of Research and Treatment of Cancer (EORTC).
Currently availabel staging systems for non-Hodgkin lymphomas are not useful for clinical staging classification of most primary cutaneous lymphomas. The tumor, node, metastases (TNM) system used for mycosis fungoides (MF) and Sézary syndrome (SS) is not appropriate for other primary cutaneous lymphomas. A usable, unified staging system would improve the communication about the state of disease, selection of appropriate management, standardization of enrollment/response criteria in clinical trials, and collection/analysis of prospective survival data. Toward this goal, during the recent meetings of the International Society for Cutaneous Lymphomas (ISCL) and the cutaneous lymphoma task force of the European Organization of Research and Treatment of Cancer (EORTC), the representatives have established a consensus proposal of a TNM classification system applicable for all primary cutaneous lymphomas other than MF and SS. Due to the clinical and pathologic heterogeneity of the cutaneous lymphomas, the currently proposed TNM system is meant to be primarily an anatomic documentation of disease extent and not to be used as a prognostic guide.
Kim
Youn H
YH
Department of Dermatology, Stanford Comprehensive Cancer Center, Stanford, CA 94305, USA. younkim@stanford.edu
Willemze
Rein
R
Pimpinelli
Nicola
N
Whittaker
Sean
S
Olsen
Elise A
EA
Ranki
Annamari
A
Dummer
Reinhard
R
Hoppe
Richard T
RT
D005060:Europe; D005260:Female; D006801:Humans; D016410:Lymphoma, T-Cell, Cutaneous / Q000145:classification* / Q000473:pathology*; D008297:Male; D009182:Mycosis Fungoides / Q000145:classification* / Q000473:pathology; D009367:Neoplasm Staging; D012751:Sezary Syndrome / Q000145:classification* / Q000473:pathology; D012878:Skin Neoplasms / Q000145:classification* / Q000473:pathology*; D012955:Societies, Medical