title: [Micro-epidemic due to a new Mycobacterium tuberculosis strain among the homeless in Budapest, Hungary].
abstract: In a retrospective study that included 66 homeless tuberculosis patients a local micro-epidemic was identified in the VIIIth district of Budapest with the highest tuberculosis incidence of the capital. Further molecular genetic characterization by IS 6110 fingerprinting, spoligotyping and mycobacterial inter-spread repetitive unit (MIRU) typing has shown that the observed micro-epidemic was due to a locally emerged, Budapest-specific lineage. The absence of infections with the more virulent Beijing genotype is also noteworthy. The findings indicate that tuberculosis control and prevention steps among the homeless need to be strengthened in Hungary.
authors.affiliation: ANTSZ Borsod-Abaúj-Zemplén Megyei Intézete Miskolc Meggyesalja 12, 3501. kodmoncs@borsod.antsz.hu
authors.forename: Csaba
authors.initials: C
authors.lastname: Ködmön
authors.forename: Judit
authors.initials: J
authors.lastname: Lukács
authors.forename: Niemann
authors.initials: N
authors.lastname: Stefan
authors.forename: Sándor
authors.initials: S
authors.lastname: Dávid
authors.forename: Imre
authors.initials: I
authors.lastname: Vadász
authors.forename: Akos
authors.initials: A
authors.lastname: Somoskövy
mesh_terms: D015373:Bacterial Typing Techniques / Q000379:methods; D016172:DNA Fingerprinting; D004269:DNA, Bacterial / Q000302:isolation & purification; D006703:Ill-Housed Persons / Q000706:statistics & numerical data*; D006801:Humans; D006814:Hungary / Q000453:epidemiology; D009169:Mycobacterium tuberculosis / Q000235:genetics*; D012189:Retrospective Studies; D014397:Tuberculosis, Pulmonary / Q000453:epidemiology* / Q000382:microbiology*
chemical_list: D004269:DNA, Bacterial