title: Radioimmunoassay for the quantitative determination of quinine in cultured plant tissues.
abstract: The development of a radioimmunossay for the determination of picogram amounts of quinine is described. The antiserum, raised against a conjugate of quinine and bovine serum albumin, is highly specific to the CINCHONA quinoline alkaloids having the 8S configuration and will not cross-react to any detectable extent with the 8R series. Neither will it cross-react with quininone or cinchonidinone, the common 9-keto precursors. Using this assay a number of clones of C. LEDGERIANA have been screened for their quinine content.
authors.affiliation: Agricultural and Food Research Council, Food Research Institute, Colney Lane, Norwich NR4 7UA, U.K.
authors.forename: R J
authors.initials: RJ
authors.lastname: Robins
authors.forename: A J
authors.initials: AJ
authors.lastname: Webb
authors.forename: M J
authors.initials: MJ
authors.lastname: Rhodes
authors.forename: J
authors.initials: J
authors.lastname: Payne
authors.forename: M R
authors.initials: MR
authors.lastname: Morgan