title: Prolonged postoperative altered mental status after methylene blue infusion during parathyroidectomy: a case report and review of the literature.
abstract: Methylene blue (5 mg/kg) is routinely given at our institution during parathyroidectomy. The dye stains the parathyroid glands and helps in better surgical visualisation. The technique is generally considered to be safe except for causing pseudo-cyanosis. We report a case of a patient who had confusion, agitation and altered mental status during the early postoperative course probably secondary to methylene blue infusion.
authors.affiliation: Department of Surgery, Chesterfield and North Derby Royal Hospital, Calow, Chesterfield, UK. drmaskhan@gmail.com
authors.forename: M A S
authors.initials: MA
authors.lastname: Khan
authors.forename: A P
authors.initials: AP
authors.lastname: North
authors.forename: D R
authors.initials: DR
authors.lastname: Chadwick
mesh_terms: D000368:Aged; D004396:Coloring Agents / Q000009:adverse effects*; D003221:Confusion / Q000139:chemically induced; D005260:Female; D006801:Humans; D006961:Hyperparathyroidism / Q000601:surgery; D008751:Methylene Blue / Q000009:adverse effects*; D016105:Parathyroidectomy; D011595:Psychomotor Agitation / Q000209:etiology; D011605:Psychoses, Substance-Induced / Q000209:etiology*
chemical_list: D004396:Coloring Agents; D008751:Methylene Blue