Clonal duplication of a germline PTPN11 mutation due to acquired uniparental disomy in acute lymphoblastic leukemia blasts from a patient with Noonan syndrome.
Karow
A
A
Steinemann
D
D
Göhring
G
G
Hasle
H
H
Greiner
J
J
Harila-Saari
A
A
Flotho
C
C
Zenker
M
M
Schlegelberger
B
B
Niemeyer
C M
CM
Kratz
C P
CP
D002648:Child; D002675:Child, Preschool; D018095:Germ-Line Mutation; D006801:Humans; D047908:Intracellular Signaling Peptides and Proteins / Q000235:genetics*; D009634:Noonan Syndrome / Q000235:genetics* / Q000473:pathology; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000235:genetics* / Q000473:pathology; D054592:Protein Tyrosine Phosphatase, Non-Receptor Type 11; D017027:Protein Tyrosine Phosphatases / Q000235:genetics*; D024182:Uniparental Disomy
D047908:Intracellular Signaling Peptides and Proteins; C516724:PTPN11 protein, human; D054592:Protein Tyrosine Phosphatase, Non-Receptor Type 11; D017027:Protein Tyrosine Phosphatases