title: Polarizability of G4-DNA observed by electrostatic force microscopy measurements.
abstract: G4-DNA, a quadruple helical motif of stacked guanine tetrads, is stiffer and more resistant to surface forces than double-stranded DNA (dsDNA), yet it enables self-assembly. Therefore, it is more likely to enable charge transport upon deposition on hard supports. We report clear evidence of polarizability of long G4-DNA molecules measured by electrostatic force microscopy, while coadsorbed dsDNA molecules on mica are electrically silent. This is another sign that G4-DNA is potentially better than dsDNA as a conducting molecular wire.
authors.affiliation: Physical Chemistry Department and Center for Nanoscience and Nanotechnology, The Hebrew University, Jerusalem 91904, Israel.
authors.forename: Hezy
authors.initials: H
authors.lastname: Cohen
authors.forename: Tomer
authors.initials: T
authors.lastname: Sapir
authors.forename: Natalia
authors.initials: N
authors.lastname: Borovok
authors.forename: Tatiana
authors.initials: T
authors.lastname: Molotsky
authors.forename: Rosa
authors.initials: R
authors.lastname: Di Felice
authors.forename: Alexander B
authors.initials: AB
authors.lastname: Kotlyar
authors.forename: Danny
authors.initials: D
authors.lastname: Porath
mesh_terms: D016880:Anisotropy; D004247:DNA / Q000737:chemistry*; D004553:Electric Conductivity; D054856:G-Quadruplexes; D018625:Microscopy, Atomic Force / Q000379:methods*; D008968:Molecular Conformation; D049329:Nanostructures / Q000737:chemistry*; D055672:Static Electricity
chemical_list: D004247:DNA