Antibiotics from Algae XXXIII1: Phlorotannins of the Brown Alga Himanthalia elongata2,3.
It is possible to obtain approximately 0.2% (relative to dry weight) phenols soluble in ethyl acetate from HIMANTHALIA ELONGATA. After removal of a fraction containing high-molecular weight substances, a total of 17 oligomeric phlorotannins with 2 to 8 aromatic rings can be isolated from the mixture of the acetylated phenol fraction. Apart from 2 derivatives belonging to the fucol group, diphlorethol and a tetraphlorethol not yet fully identified, all the other substances are fucophlorethols. Amongst these substances, a phenoxylated therphenyl derivative and several fucophlorethols with two-fold phenoxy-substituted biphenyl moieties were identified for the first time.
Glombitza
K W
KW
Institut für Pharmazeutische Biologie, Universität Bonn, Nußallee 6, D-5300 Bonn 1, West Germany.
Große-Damhues
J
J