A new asymmetric organocatalytic nitrocyclopropanation reaction.
Using 5-(pyrrolidin-2-yl)-1H-tetrazole as an organic catalyst, the nitrocyclopropanation of 2-cyclohexen-1-one has been achieved, proceeding in high yield and with good enantioselective control.
Hansen
Henriette M
HM
Department of Chemistry, University of Cambridge, Lensfield Rd, Cambridge, UK CB2 1EW.
Longbottom
Deborah A
DA
Ley
Steven V
SV