Susceptibility of drug-resistant clinical herpes simplex virus type 1 strains to essential oils of ginger, thyme, hyssop, and sandalwood.
Acyclovir-resistant clinical isolates of herpes simplex virus type 1 (HSV-1) were analyzed in vitro for their susceptibilities to essential oils of ginger, thyme, hyssop, and sandalwood. All essential oils exhibited high levels of virucidal activity against acyclovir-sensitive strain KOS and acyclovir-resistant HSV-1 clinical isolates and reduced plaque formation significantly.
Schnitzler
Paul
P
Hygiene Institute, Department of Virology, University of Heidelberg, Im Neuenheimer Feld 324, Heidelberg, Germany. Paul_Schnitzler@med.uni-heidelberg.de
Koch
Christine
C
Reichling
Jürgen
J
D000212:Acyclovir / Q000494:pharmacology; D024882:Drug Resistance, Viral; D020939:Zingiber officinale; D018259:Herpesvirus 1, Human; D019686:Lamiaceae; D008826:Microbial Sensitivity Tests; D009822:Oils, Volatile / Q000494:pharmacology*; D032123:Santalum; D046930:Thymus Plant
D009822:Oils, Volatile; D000212:Acyclovir