Video documented follow-up of liver transplantation in Wilson's disease with predominant neurological manifestation.
Wilson's disease (WD) is a rare autosomal-recessive disorder of copper metabolism with predominantly hepatic and extrapyramidal motor symptoms. Copper chelating therapy has proven to be an effective treatment for WD. Yet, if conservative treatment fails, liver transplantation (LT) often is the only remaining therapeutic option. The indication for LT especially in patients with stable liver function but severe neurological manifestation is debated controversially. In this case report, we document the follow up of neurological symptoms in WD after LT for the first time on video.
Suess
Thorsten
T
Department of Neurology, Medizinische Hochschule Hannover, Hannover, Germany. thorsten.suess@web.de
Bokemeyer
Martin
M
Schomerus
Georg
G
Donnerstag
Frank
F
Manns
Michael Peter
MP
Klempnauer
Juergen
J
Kolbe
Hans
H
Weissenborn
Karin
K
D000328:Adult; D005500:Follow-Up Studies; D006527:Hepatolenticular Degeneration / Q000473:pathology / Q000503:physiopathology* / Q000601:surgery*; D006801:Humans; D016031:Liver Transplantation / Q000379:methods*; D008297:Male; D009422:Nervous System Diseases / Q000503:physiopathology* / Q000628:therapy*; D013788:Thalamus / Q000473:pathology; D014741:Video Recording / Q000379:methods