title: [Preparation of inclusion complex of daidzein and hydropropyl-beta-cyclodextrin].
abstract: OBJECTIVE
  To prepare an inclusion complex of daidzein and hydropropyl-beta-cyclodextrin to enhance the solubility of daidzein.
  
  
  METHODS
  The inclusion complex of daidzein was prepared by the solution stirring method. The binary system of daidzein and HP-beta-CD was confirmed by differential thermal, thermogravimetry analysis, infrared spectroscopy and X-ray diffractometry.
  
  
  RESULTS
  The drug content in the inclusion complex was 6. 76% and the solubility was 13.68 mg x mL(-1). The identification results showed that the inclusion complex was formed.
  
  
  CONCLUSIONS
  The preparation method of the inclusion complex of daidzein and hydropropyl-beta-cyclodextrin is simple and available, with a increased solubility of daidzein.
authors.affiliation: Center of Ocean, Department of Biology Sciences and Biotechnology, Tsinghua University, Beijing 100084, China.
authors.forename: Yue-Bin
authors.initials: YB
authors.lastname: Ge
authors.forename: Da-Wei
authors.initials: DW
authors.lastname: Chen
authors.forename: Li-Ping
authors.initials: LP
authors.lastname: Xie
authors.forename: Hong-Zhong
authors.initials: HZ
authors.lastname: Wang
authors.forename: Gui-Lan
authors.initials: GL
authors.lastname: Zheng
authors.forename: Rong-Qing
authors.initials: RQ
authors.lastname: Zhang
mesh_terms: D000073738:2-Hydroxypropyl-beta-cyclodextrin; D004055:Differential Thermal Analysis; D004339:Drug Compounding / Q000379:methods*; D007529:Isoflavones / Q000737:chemistry*; D012995:Solubility; D017550:Spectroscopy, Fourier Transform Infrared; D014961:X-Ray Diffraction; D047392:beta-Cyclodextrins / Q000737:chemistry*
chemical_list: D007529:Isoflavones; D047392:beta-Cyclodextrins; D000073738:2-Hydroxypropyl-beta-cyclodextrin; C004742:daidzein