Immunohistochemical expression of COX-2 and c-kit in metastatic uveal melanoma.
METHODS
We report a case of choroidal melanoma metastatic to the liver diagnosed by fine-needle aspiration. The biopsy sample was immunostained for COX-2 and c-kit.


CONCLUSIONS
Accurate diagnosis and identification of potential therapeutic targets are important for subsequent therapy and can be achieved by radiologically guided fine-needle aspiration biopsy.
Frota
Ana C A
AC
Department of Ophthalmology, Federal University of São Paulo, Brazil. carolafrota@click21.com.br
Odashiro
Alexandre N
AN
Pereira
Patricia R
PR
Fernandes
Bruno F
BF
Godeiro
Katyanne Dantas
KD
Filho
Joao Pessoa Souza
JP
Burnier
Miguel N
MN
D000368:Aged; D001707:Biopsy, Needle; D002830:Choroid Neoplasms / Q000378:metabolism* / Q000473:pathology; D051546:Cyclooxygenase 2 / Q000378:metabolism*; D006801:Humans; D007150:Immunohistochemistry; D008113:Liver Neoplasms / Q000378:metabolism* / Q000556:secondary; D008297:Male; D008545:Melanoma / Q000378:metabolism* / Q000556:secondary; D019009:Proto-Oncogene Proteins c-kit / Q000378:metabolism*
D051546:Cyclooxygenase 2; D019009:Proto-Oncogene Proteins c-kit