Die Alkaloide von Uncaria tomentosa und ihre Phagozytose-steigernde Wirkung.
From the roots of UNCARIA TOMENTOSA six oxindol alkaloids have been isolated and identified as isopteropodin, pteropodin, mitraphyllin, isomitraphyllin, rynchophyllin and isorynchophyllin. By ion pair chromatography on HPLC a fingerprint analysis has been worked out which allowed to differentiate between various UNICARIA-species and drug preparations. With the exception of mitraphyllin and rynchophyllin all alkaloids showed a pronounced enhancement effect on phagozytosis, determined in two IN VITRO tests and the IN VIVO-carbon clearance test.
Wagner
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H
Institut für Pharmazeutische Biologie der Universität München, D-8000 München 2, Karlstraße 29.
Kreutzkamp
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B
Jurcic
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