title: Frequency of cytokine gene promoter polymorphisms in the Northern Ireland cystic fibrosis population.
abstract: It has been postulated that cytokine allele frequencies are gender and perhaps geographically-specific. Cytokine release is crucial in the regulation of the type and magnitude of the immune response. This study observed no differences in the frequency of cytokine promoter polymorphisms associated with variant levels of expression in patients with CF and a non-CF population of Northern Ireland.
authors.affiliation: Respiratory Research Group, The Queen's University of Belfast, United Kingdom. Alison.Watt@bll.n-i.nhs.uk
authors.forename: Alison P
authors.initials: AP
authors.lastname: Watt
authors.forename: Owen A
authors.initials: OA
authors.lastname: Ross
authors.forename: Julia
authors.initials: J
authors.lastname: Courtney
authors.forename: Derek
authors.initials: D
authors.lastname: Middleton
authors.forename: Madeleine
authors.initials: M
authors.lastname: Ennis
authors.forename: J Stuart
authors.initials: JS
authors.lastname: Elborn
mesh_terms: D000328:Adult; D003550:Cystic Fibrosis / Q000453:epidemiology / Q000235:genetics*; D016207:Cytokines / Q000235:genetics*; D005260:Female; D005787:Gene Frequency; D006801:Humans; D008297:Male; D008875:Middle Aged; D009660:Northern Ireland / Q000453:epidemiology; D011110:Polymorphism, Genetic; D011401:Promoter Regions, Genetic / Q000235:genetics*
chemical_list: D016207:Cytokines