title: Acromegaly presented as a cause of laryngeal dyspnea.
abstract: Acromegalic patients can develop obstructive sleep apnea syndrome or upper airflow obstruction. The development of dyspnea is unusual and the fixation of both vocal cords is exceptional. We report the case of a patient with bilateral vocal cord paralysis. Fiberoptic laryngoscopy and computed tomography (CT) of the neck showed a supra-glottic stenosis due to a swelling of the soft tissue. A tracheostomy was first performed. Thereafter, micro-laryngoscopy using laser vaporisation of the supra-glottic soft tissue was attempted but failed to remove the tracheostomy canula. Finally, blood tests and cerebral MRI revealed an acromegaly. The patient underwent a trans-sphenoidal resection of the pituitary adenoma. Fifteen months later, fiberoptic laryngoscopy showed bilateral restoration of vocal cord mobility and the tracheostomy canula was successfully removed after 18 months. Vocal cord fixation is probably due to hypopharyngeal and laryngeal soft tissue swelling and can be reversible after successful treatment of the adenoma.
authors.affiliation: Department of Otorhinolaryngology, Head and Neck Surgery, CHU Saint-Pierre, Brussels, Belgium. Sven.saussez@skynet.be
authors.forename: S
authors.initials: S
authors.lastname: Saussez
authors.forename: V
authors.initials: V
authors.lastname: Mahillon
authors.forename: G
authors.initials: G
authors.lastname: Chantrain
authors.forename: M P
authors.initials: MP
authors.lastname: Thill
authors.forename: T
authors.initials: T
authors.lastname: Lequeux
mesh_terms: D000172:Acromegaly / Q000150:complications* / Q000175:diagnosis / Q000601:surgery; D000402:Airway Obstruction / Q000175:diagnosis / Q000209:etiology* / Q000601:surgery; D003937:Diagnosis, Differential; D004417:Dyspnea / Q000209:etiology*; D049912:Growth Hormone-Secreting Pituitary Adenoma / Q000150:complications / Q000175:diagnosis / Q000601:surgery; D006801:Humans; D007016:Hypophysectomy; D007818:Laryngeal Diseases / Q000175:diagnosis / Q000209:etiology* / Q000601:surgery; D007828:Laryngoscopy; D008297:Male; D008875:Middle Aged; D010911:Pituitary Neoplasms / Q000150:complications / Q000175:diagnosis / Q000601:surgery; D014057:Tomography, X-Ray Computed; D014826:Vocal Cord Paralysis / Q000175:diagnosis / Q000209:etiology* / Q000601:surgery