title: Social support, optimism, and self-efficacy predict physical and emotional well-being after bone marrow transplantation.
abstract: This study examined whether three psychosocial variables (social support, self-efficacy, and optimism) assessed prior to bone marrow transplantation (BMT) predicted physical and emotional wellbeing one year post-BMT. Data were gathered on 87 participants enrolled in a multicenter, randomized trial examining the impact of ex-vivo T-cell depletion on disease-free survival in leukemia patients receiving allogeneic BMT. Social support, optimism, and self-efficacy significantly predicted emotional and physical well-being one year post-BMT, controlling for age, gender, maximum grade of acute GVHD, and treatment arm. Attention to psychosocial factors prior to BMT and during recovery appears critical for physical and mental well-being, especially considering the influence of psychosocial variables independent of medical risk factors.
authors.affiliation: The University of Iowa, Iowa City, IA 52242, USA.
authors.forename: Nicole
authors.initials: N
authors.lastname: Hochhausen
authors.forename: Elizabeth M
authors.initials: EM
authors.lastname: Altmaier
authors.forename: Richard
authors.initials: R
authors.lastname: McQuellon
authors.forename: Stella M
authors.initials: SM
authors.lastname: Davies
authors.forename: Esperanza
authors.initials: E
authors.lastname: Papadopolous
authors.forename: Shelly
authors.initials: S
authors.lastname: Carter
authors.forename: Jean
authors.initials: J
authors.lastname: Henslee-Downey
mesh_terms: D000293:Adolescent; D000328:Adult; D000339:Affect; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D016026:Bone Marrow Transplantation / Q000379:methods*; D016572:Cyclosporine / Q000627:therapeutic use; D005260:Female; D006086:Graft vs Host Disease / Q000517:prevention & control; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008297:Male; D008727:Methotrexate / Q000627:therapeutic use; D008875:Middle Aged; D010809:Physical Fitness; D011584:Psychology; D020377:Self Efficacy; D012944:Social Support
chemical_list: D007166:Immunosuppressive Agents; D016572:Cyclosporine; D008727:Methotrexate