title: Preservation of renal function utilizing hypothermic circulatory arrest in the treatment of distal thoracoabdominal aneurysms (types III and IV).
abstract: Although left heart bypass and hypothermia are often used in the performance of type I and type II thoracoabdominal aneurysms (TAAs), most of these more distal aneurysms are done utilizing the clamp and sew technique. Renal failure occurs between 8.6% to 39% in recent series of patients following surgery for type III and IV TAAs. The purpose of this study was to determine whether the use of hypothermic circulatory arrest in these cases would serve to protect renal function. All patients were operated on using hypothermic circulatory arrest. The kidneys were perfused with cold blood during the procedures, and renal artery bypasses were aggressively used (when stenoses greater than 50% were observed). The series describes 33 consecutive patients with type III and IV TAAs who were operated on utilizing hypothermic circulatory arrest with a core temperature of 15 degrees centigrade. All visceral and renal arteries were individually perfused; 20 patients had bypass grafts of their renal artery stenoses. Although six patients had renal failure preoperatively, only one developed postoperative renal failure. This was the patient who was operated on as an emergency for severe abdominal pain, back pain, and acidosis who was also the only hospital death. Of the remaining five patients with elevated creatinines preoperatively, four had postoperative decrease of the serum creatinine. One patient developed paraparesis and one developed a stroke. The median length of stay was 8 days. Consideration should be given to the use of hypothermic circulatory arrest in type III and IV TAAs for the preservation of renal function and improved overall results.
authors.affiliation: Methodist Hospital of Indiana, Indianapolis, IN, USA.
authors.forename: John
authors.initials: J
authors.lastname: Fehrenbacher
authors.forename: Harry
authors.initials: H
authors.lastname: Siderys
authors.forename: Ali
authors.initials: A
authors.lastname: Shahriari
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000714:Anastomosis, Surgical; D017544:Aortic Aneurysm, Abdominal / Q000150:complications / Q000503:physiopathology / Q000601:surgery*; D017545:Aortic Aneurysm, Thoracic / Q000150:complications / Q000503:physiopathology / Q000601:surgery*; D002315:Cardiopulmonary Bypass; D050792:Circulatory Arrest, Deep Hypothermia Induced; D005260:Female; D006801:Humans; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D010264:Paraplegia / Q000209:etiology / Q000517:prevention & control; D012077:Renal Artery / Q000601:surgery; D012078:Renal Artery Obstruction / Q000150:complications / Q000503:physiopathology / Q000601:surgery*; D012079:Renal Circulation; D051437:Renal Insufficiency / Q000209:etiology / Q000503:physiopathology / Q000517:prevention & control*; D012720:Severity of Illness Index; D016896:Treatment Outcome; D014656:Vascular Surgical Procedures / Q000009:adverse effects*