[Cardiac imaging in ANCA-associated vasculitis].
Churg-Strauss syndrome and Wegener granulomatosis are the two principal ANCA-associated vasculitides. Cardiac damage is frequent and prognosis poor. This damage is often subclinical initially and undetectable with standard cardiac imaging techniques (such as cardiac ultrasound or myocardial scintigraphy). Cardiac MRI permits early diagnosis of the different types of cardiac damage (myocarditis, pericarditis, and impaired myocardiac perfusion) that may occur during ANCA-associated vasculitis, even before the onset of symptoms. Early detection of this cardiac damage is crucial for it enables faster implementation of aggressive treatment, which may significantly improve disease prognosis. The widespread, even routine, practice of cardiac MRI in patients with ANCA-associated vasculitis thus seems justified, for this noninvasive examination provides essential diagnostic and prognostic information and helps guide therapeutic management.
Vignaux
Olivier
O
Service de radiologie A, Hopital Cochin, Paris, France. olivier.vignaux@cch.aphp.fr
Marmursztejn
Julien
J
Cohen
Pascal
P
Bruguière
Eric
E
Duboc
Denis
D
Guillevin
Loïc
L
Legmann
Paul
P
D019268:Antibodies, Antineutrophil Cytoplasmic; D015267:Churg-Strauss Syndrome / Q000175:diagnosis*; D003326:Coronary Circulation; D003327:Coronary Disease / Q000175:diagnosis; D004452:Echocardiography; D014890:Granulomatosis with Polyangiitis / Q000175:diagnosis*; D006331:Heart Diseases / Q000175:diagnosis*; D006349:Heart Valve Diseases / Q000175:diagnosis; D006801:Humans; D008279:Magnetic Resonance Imaging; D010490:Pericardial Effusion / Q000175:diagnosis; D011379:Prognosis; D013997:Time Factors
D019268:Antibodies, Antineutrophil Cytoplasmic