Palladium-catalyzed arylation of electron-rich heterocycles with aryl chlorides.
[reaction: see text] Palladium-catalyzed C-H activation: cheap aryl chlorides can now be used for the arylation of a wide variety of electron-rich heterocycles. The key to the success of this reaction is the use of a bulky, electron-rich phosphine ligand. No copper additives are needed.
Chiong
Hendrich A
HA
Department of Chemistry, University of Houston, Houston, Texas 77204, USA.
Daugulis
Olafs
O