title: Randomized clinical trial comparing two options for postoperative incisional care to prevent poststernotomy surgical site infections.
abstract: Surgical site infection (SSI) remains an important complication of cardiac surgery. Prevention is important, as SSI is associated with high mortality and morbidity rates. Incisional care is an important daily issue for surgeons. However, there is still scant scientific evidence on which guidelines can be based. A randomized clinical trial was performed to compare two options for postoperative incisional care. Patients undergoing sternotomy for cardiothoracic surgery were eligible. To protect an incision from exogenous contamination or direct inoculation by endogenous pathogens, the study group received an adhesive drape, impermeable to water and air. The control group was treated with a water- and air-permeable absorbent dressing. Primary outcome measure was SSI. Between March 2003 and January 2005, 1,185 patients were included. Both groups were comparable for base-line characteristics. No significant difference was found in the incidence of sternal SSI between groups (2.6 vs. 3.3%). In our study, an incisional-care program using a sterile, impermeable adhesive drape did not perform better than an absorbent dressing in reducing SSI after cardiothoracic surgery. In our view, future studies in the field of prevention of SSI should concentrate on other areas of interest.
authors.affiliation: Department of Cardiothoracic Surgery, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands. p.segers@amc.uva.nl
authors.forename: Patrique
authors.initials: P
authors.lastname: Segers
authors.forename: Antonius P
authors.initials: AP
authors.lastname: de Jong
authors.forename: Lodewijk
authors.initials: L
authors.lastname: Spanjaard
authors.forename: Dirk T
authors.initials: DT
authors.lastname: Ubbink
authors.forename: Bas A J M
authors.initials: BA
authors.lastname: de Mol
mesh_terms: D000368:Aged; D001458:Bandages; D006348:Cardiac Surgical Procedures; D001026:Coronary Artery Bypass; D005260:Female; D006349:Heart Valve Diseases / Q000601:surgery; D006801:Humans; D008297:Male; D008875:Middle Aged; D011182:Postoperative Care / Q000379:methods*; D017410:Practice Guidelines as Topic; D013249:Sternum / Q000382:microbiology / Q000601:surgery; D013530:Surgical Wound Infection / Q000517:prevention & control*; D019616:Thoracic Surgical Procedures