title: [Application of supercritical solution rapid expansion technology in preparation of fine pharmacal particles].
abstract: Rapid expansion of supercritical solution (RESS), a new technology, has been developed in the recent years. Fundamental principle of RESS technology used to prepare fine pharmacal particles was summarized in this paper. A brief review of factors which influenced the process of RESS and application of RESS technology were introduced.
authors.affiliation: Department of Pharmacy, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, China. zhang43499@sohu.com
authors.forename: Zhong-yi
authors.initials: ZY
authors.lastname: Zhang
authors.forename: Hong-lei
authors.initials: HL
authors.lastname: Li
authors.forename: Zheng-jie
authors.initials: ZJ
authors.lastname: Lei
mesh_terms: D003460:Crystallization / Q000379:methods; D003692:Delayed-Action Preparations; D049329:Nanostructures; D010316:Particle Size; D004364:Pharmaceutical Preparations / Q000737:chemistry*; D012995:Solubility; D012996:Solutions; D013678:Technology, Pharmaceutical / Q000295:instrumentation* / Q000379:methods*; D013696:Temperature
chemical_list: D003692:Delayed-Action Preparations; D004364:Pharmaceutical Preparations; D012996:Solutions