Posaconazole treatment for Apophysomyces elegans rhino-orbital zygomycosis following trauma for a male with well-controlled diabetes.
We report a case of rhino-orbital zygomycosis in a 43-year-old male with well-controlled diabetes mellitus. The patient initially received liposomal amphotericin B, but the infection continued to progress, so posaconazole treatment was begun and eventually led to the cure of his infection. The causative agent was identified as Apophysomyces elegans, an emerging cause of zygomycosis in immunocompetent hosts.
Ferguson
T D
TD
Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, USA.
Schniederjan
S D
SD
Dionne-Odom
J
J
Brandt
M E
ME
Rinaldi
M G
MG
Nolte
F S
FS
Langston
A
A
Zimmer
S M
SM
D000328:Adult; D000935:Antifungal Agents / Q000627:therapeutic use; D003881:Dermatomycoses / Q000188:drug therapy* / Q000382:microbiology* / Q000601:surgery; D003920:Diabetes Mellitus; D005658:Fungi / Q000302:isolation & purification*; D006801:Humans; D008297:Male; D014230:Triazoles / Q000627:therapeutic use*; D020096:Zygomycosis / Q000188:drug therapy* / Q000382:microbiology* / Q000601:surgery
D000935:Antifungal Agents; D014230:Triazoles; C101425:posaconazole