Follicular lymphoma with extensive gastrointestinal tract involvement: follow-up by capsule endoscopy.
Follicular lymphoma with gastrointestinal tract involvement is rare. We describe the case of a young woman with follicular lymphoma with multiple nodular lesions involving segments of the proximal jejunum and terminal ileum. The presenting symptom was chronic diarrhea. The diagnosis was made by endoscopy with histologic examination of the mucosal lesions of the proximal and distal small intestine, immunohistochemical staining, and molecular analysis. The initial spread and pattern of the small bowel involvement, as well as treatment response, were evaluated by videocapsule endoscopy. The application of molecular analysis along with immunophenotypic evaluation has made it possible to precisely diagnose follicular lymphoma. In the present case, the use of capsule endoscopy improved the evaluation of the extent of small bowel involvement prior to and following treatment.
Sapoznikov
Boris
B
Department of Gastroenterology, Rabin Medical Center, Tel Aviv University, Beilinson Campus, Petah Tiqwa 49100, Israel.
Morgenstern
Sarah
S
Raanani
Pia
P
Aviram
Adina
A
Rabizadeh
Esther
E
Prokocimer
Miron
M
Niv
Yaron
Y
D000328:Adult; D001706:Biopsy; D053704:Capsule Endoscopy; D005260:Female; D006801:Humans; D007078:Ileal Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy; D007413:Intestinal Mucosa / Q000473:pathology; D007580:Jejunal Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy; D008224:Lymphoma, Follicular / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy