title: In vitro cytotoxic activity of Brazilian plant extracts against human lung, colon and CNS solid cancers and leukemia.
abstract: The cytotoxicity of extracts obtained from plants occurring in the Amazon and Atlantic rain forests against NCI-H460, KM-12, SF-268 and RPMI-8226 cancer cell lines was investigated. Expressive activity was observed in the extracts of Toulicia cf. pulvinata, Ampirrhox sp., Macoubea sprucei, Calophyllum brasiliense, Vismia guianensis, Caryocar microcarpum, Xylopia aromatica and Distictella magnoliifolia.
authors.affiliation: Laboratório de Extração da Universidade Paulista - UNIP, São Paulo, SP, Brazil.
authors.forename: Ivana B
authors.initials: IB
authors.lastname: Suffredini
authors.forename: Mateus L B
authors.initials: ML
authors.lastname: Paciencia
authors.forename: Antonio D
authors.initials: AD
authors.lastname: Varella
authors.forename: Riad N
authors.initials: RN
authors.lastname: Younes
mesh_terms: D000972:Antineoplastic Agents, Phytogenic / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D001938:Brazil; D045744:Cell Line, Tumor / Q000187:drug effects; D006801:Humans; D008519:Medicine, Traditional; D008517:Phytotherapy; D010936:Plant Extracts / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D010946:Plants, Medicinal
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D010936:Plant Extracts