title: Step down procedure for comparing several treatments with a control based on multivariate normal response.
abstract: In this study we consider a multiple comparison of several treatments with a control based on multivariate normal response in clinical trials. Specifically we construct a step down procedure by referring to Dunnett and Tamhane (1991). Furthermore we formulate the all-pairs power by using the recursive formula derived by Hayter and Tamhane (1991) and Dunnett, Horn and Vollandt (2001). Finally we compare the step down procedure with the single step procedure proposed by Nakamura and Imada (2005) in terms of some numerical examples regarding the power of the test.
authors.affiliation: Kumamoto Liberal Arts Education, Division of Liberal Arts Education, Kyushu Tokai University, 9-1-1 Toroku, Kumamoto 862-8652, Japan. timada@ktmail.ktokai-u.ac.jp
authors.forename: Tsunehisa
authors.initials: T
authors.lastname: Imada
authors.forename: Hideyuki
authors.initials: H
authors.lastname: Douke
mesh_terms: D003627:Data Interpretation, Statistical; D015999:Multivariate Analysis; D016032:Randomized Controlled Trials as Topic / Q000706:statistics & numerical data*