Asymptomatic bacteriuria in pregnancy.
Screening for asymptomatic bacteriuria is a standard of obstetrical care and is included in most antenatal guidelines. There is good evidence that treatment of asymptomatic bacteriuria will decrease the incidence of pyelonephritis. All pregnant women should be screened for asymptomatic bacteriuria, and there are no new data that would indicate otherwise. Antibiotic treatment of asymptomatic bacteriuria is associated with a decrease in the incidence of preterm delivery or low birth weight, but the methodological quality of the studies means any conclusion about the strength of this association needs to be drawn cautiously. A better understanding of the mechanism by which treatment of asymptomatic bacteriuria could prevent preterm delivery is needed. While several rapid screening tests have been evaluated, none perform adequately to replace urine culture for detecting asymptomatic bacteriuria. Until there are data from well-designed trials that establish the optimal duration of therapy for asymptomatic bacteriuria, standard treatment courses are recommended.
Smaill
Fiona
F
Department of Pathology and Molecular Medicine, Faculty of Health Sciences, McMaster University, McMaster University Medical Centre, Hamilton, Ontario, Canada. smaill@mcmaster.ca <smaill@mcmaster.ca>
D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D001437:Bacteriuria / Q000175:diagnosis* / Q000382:microbiology / Q000628:therapy*; D005260:Female; D006801:Humans; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000175:diagnosis* / Q000382:microbiology / Q000628:therapy*; D011256:Pregnancy Outcome
D000900:Anti-Bacterial Agents