Steroid treatment in children with sickle-cell disease.
Given the controversy concerning the effects of steroids in patients with sickle cell disease (SCD), we evaluated the tolerability of long-term steroid treatment in 16 children with SCD and autoimmune and/or systemic diseases. The steroid treatment was poorly tolerated.
Couillard
Sonia
S
Benkerrou
Malika
M
Girot
Robert
R
Brousse
Valentine
V
Ferster
Alicia
A
Bader-Meunier
Brigitte
B
D000293:Adolescent; D000755:Anemia, Sickle Cell / Q000150:complications* / Q000188:drug therapy / Q000628:therapy; D001168:Arthritis / Q000150:complications / Q000188:drug therapy; D001327:Autoimmune Diseases / Q000150:complications / Q000188:drug therapy*; D001803:Blood Transfusion; D002648:Child; D002675:Child, Preschool; D003131:Combined Modality Therapy; D004198:Disease Susceptibility; D004341:Drug Evaluation; D005078:Exchange Transfusion, Whole Blood; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006918:Hydroxyurea / Q000627:therapeutic use; D007166:Immunosuppressive Agents / Q000009:adverse effects* / Q000627:therapeutic use; D007223:Infant; D007238:Infarction / Q000209:etiology; D007239:Infections / Q000209:etiology; D007668:Kidney / Q000098:blood supply; D007958:Leukocyte Count; D008297:Male; D010146:Pain / Q000209:etiology; D011241:Prednisone / Q000009:adverse effects* / Q000627:therapeutic use; D012189:Retrospective Studies; D012507:Sarcoidosis / Q000150:complications / Q000188:drug therapy; D020521:Stroke / Q000209:etiology; D016896:Treatment Outcome; D014652:Vascular Diseases / Q000209:etiology / Q000517:prevention & control
D007166:Immunosuppressive Agents; D011241:Prednisone; D006918:Hydroxyurea