[Biological premisses and therapeutic effect of immunological treatment with antilymphocytic globulin via the coeliac artery in hepatitis of immunological origin].
The morphology of organ transplant rejection indicates that the circulation biophysics of the immunocompetent cells in the transplant capillaries is one of the most aspects of immune reaction haemodynamics. In the same way, the compromise of the liver-spleen arterial circulation observed in hepatitis of immunological origin may be interpreted on the basis of the spread of cellular aggregates, primarily lymphocytes whose reduced electrophoretic mobility is due to their being immunised with respect to the hepatic antigen. An immunological treatment, consisting of the perfusion of the liver with antilymphocyte globulins and other additives via the coeliac artery with the object of modifying the complex physico-chemical changes in the disturbed immunological dynamics, was carried out in 3 cases of hepatitis. The therapeutic results and their evaluation via a number of functional parameters are discussed.
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Università di Napoli.
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D000293:Adolescent; D000328:Adult; D000961:Antilymphocyte Serum / Q000008:administration & dosage*; D002445:Celiac Artery; D019693:Hepatitis, Autoimmune / Q000188:drug therapy*; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage*; D007261:Infusions, Intra-Arterial
D000961:Antilymphocyte Serum; D007166:Immunosuppressive Agents