title: Single-stage transanal endorectal pull-through for Hirschsprung's disease: perspective from a developing country.
abstract: OBJECTIVE
  The aim of this study was to evaluate the feasibility, results, and cost-effectiveness of totally transanal endorectal pull-through (TEPT) in the management of rectosigmoid and midsigmoid Hirschsprung's disease (HD) in a low-income country.
  
  
  METHODS
  Between March 2004 and December 2005, 19 children underwent totally TEPT procedure. The patients' ages ranged from 6 days to 13 years. The primary diagnosis in all 19 patients was HD confined to the rectosigmoid region in 15 and midsigmoid in 4. None had a preoperative colostomy. Follow-up period ranged from 4 to 20 months (mean, 8 months).
  
  
  RESULTS
  Ages ranged from 0.25 to 65 months, with a mean of 16.24 months. Weights ranged from 3.4 to 13 kg, with a mean of 6.5 kg. Mean time from diagnosis to pull-through procedure was 26 days (range, 6-39 days). The mean length of rectosigmoid resection was 30 cm (range, 20-50 cm). The mean operative time was 95 minutes (range, 75-140 minutes). Mean intraoperative blood loss was 25 mL (range, 15-40 mL). There was one death unrelated to the procedure. One patient had enterocolitis 3 months postoperatively. Average frequency of defecation was 3 (range, 1-6) stools per day. TEPT was associated with a shorter operating time, less blood loss, early return to feeds, and an overall reduced cost.
  
  
  CONCLUSIONS
  The safety and cost-effective benefits of transanal endorectal pull-through in the treatment of HD are of special interest for a developing country. Our data also suggest that functional outcome following TEPT is highly satisfactory and comparable with other established procedures.
authors.affiliation: Department of Surgery, B.P. Koirala Institute of Health Sciences, Dharan, Nepal.
authors.forename: Akshay
authors.initials: A
authors.lastname: Pratap
authors.forename: Vikal Chandra
authors.initials: VC
authors.lastname: Shakya
authors.forename: Binay Kumar
authors.initials: BK
authors.lastname: Biswas
authors.forename: Arvind
authors.initials: A
authors.lastname: Sinha
authors.forename: Awadhesh
authors.initials: A
authors.lastname: Tiwari
authors.forename: Chandra Shekhar
authors.initials: CS
authors.lastname: Agrawal
authors.forename: Shailesh
authors.initials: S
authors.lastname: Adhikary
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D003362:Cost-Benefit Analysis; D003906:Developing Countries; D013505:Digestive System Surgical Procedures / Q000191:economics / Q000379:methods*; D005240:Feasibility Studies; D005260:Female; D006627:Hirschsprung Disease / Q000601:surgery*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D009390:Nepal; D011203:Poverty; D012189:Retrospective Studies