Parallel kinetic resolution of an oxazolidinone using a quasi-enantiomeric combination of [D,13C]-isotopomers of pentafluorophenyl 2-phenyl propionate.
Parallel kinetic resolution of Evans' phenylglycine derived oxazolidinone using an equimolar combination of quasi-enantiomeric active esters (derived from [D,13C]-labeled 2-phenylpropionic acid) was achieved. The levels of stereocontrol were high, leading to products with predictable configurations.
Coumbarides
Gregory S
GS
Department of Chemistry, Queen Mary, University of London, Mile End Road, London, United Kingdom.
Dingjan
Marco
M
Eames
Jason
J
Flinn
Anthony
A
Northen
Julian
J