Surgical therapies for pulmonary arterial hypertension.
Surgical therapies for the treatment of pulmonary arterial hypertension typically are reserved for patients who are deemed to be refractory to medical therapy and have evidence of progressive right-sided heart failure. Atrial septostomy, a primarily palliative procedure, may stave off hemodynamic collapse from right-sided heart failure long enough to permit a more definitive surgical treatment such as lung or combined heart-lung transplantation. This article discusses indications for and results of atrial septostomy and lung and heart-lung transplantation in patients who have pulmonary arterial hypertension.
Sager
Jeffrey S
JS
Lung Transplantation Program, Pulmonary, Allergy and Critical Care Division, University of Pennsylvania Medical Center, 828 West Gates Building, 3600 Spruce Street, Philadelphia, PA 19104, USA. sagerj@uphs.upenn.edu
Ahya
Vivek N
VN
D015150:Echocardiography, Doppler; D006084:Graft Rejection / Q000503:physiopathology; D006346:Heart Septum / Q000601:surgery; D016041:Heart-Lung Transplantation; D006801:Humans; D006976:Hypertension, Pulmonary / Q000601:surgery*; D016040:Lung Transplantation / Q000276:immunology / Q000502:physiology; D018579:Patient Selection; D011183:Postoperative Complications / Q000453:epidemiology; D011788:Quality of Life