title: DNA migration and separation on surfaces with a microscale dielectrophoretic trap array.
abstract: We studied the surface migration of DNA chains driven by a dc electric field across localized dielectrophoretic traps. By adjusting the length scale of the trap array, separation of a selected band of DNA was accomplished with a scaling exponent between mobility and number of base pairs similar to that obtained in capillary electrophoresis. We then provided a model, which predicts the trapping and extension of DNA chains at a dielectrophoretic trap responsible for the surface mobility and separation.
authors.affiliation: Harvard University, Cambridge, MA 02138, USA.
authors.forename: Eric
authors.initials: E
authors.lastname: Petersen
authors.forename: Bingquan
authors.initials: B
authors.lastname: Li
authors.forename: Xiaohua
authors.initials: X
authors.lastname: Fang
authors.forename: Haobin
authors.initials: H
authors.lastname: Luo
authors.forename: Vladimir
authors.initials: V
authors.lastname: Samuilov
authors.forename: Dilip
authors.initials: D
authors.lastname: Gersappe
authors.forename: Jonathan
authors.initials: J
authors.lastname: Sokolov
authors.forename: Benjamin
authors.initials: B
authors.lastname: Chu
authors.forename: Miriam
authors.initials: M
authors.lastname: Rafailovich
mesh_terms: D004279:DNA, Viral / Q000737:chemistry*; D004574:Electromagnetic Fields; D004586:Electrophoresis; D006046:Gold / Q000737:chemistry; D018613:Microscopy, Confocal; D009068:Movement; D012825:Silicon / Q000737:chemistry; D013499:Surface Properties
chemical_list: D004279:DNA, Viral; D006046:Gold; D012825:Silicon