Polymeric model systems for flavoenzyme activity: towards synthetic flavoenzymes.
We report the synthesis of a water-soluble flavin polymer using ATRP, whereby the oligoethylene glycol backbone provides both a local hydrophobic environment and redox tuning of the flavin moiety typical of flavoenzyme prototypes.
Jordan
Brian J
BJ
Department of Chemistry, University of Massachusetts at Amherst, Amherst, MA 01003, USA.
Cooke
Graeme
G
Garety
James F
JF
Pollier
Michael A
MA
Kryvokhyzha
Nadiya
N
Bayir
Ali
A
Rabani
Gouher
G
Rotello
Vincent M
VM
D004798:Enzymes / Q000737:chemistry*; D005415:Flavins / Q000737:chemistry*; D008958:Models, Molecular; D011487:Protein Conformation; D013056:Spectrophotometry, Ultraviolet
D004798:Enzymes; D005415:Flavins