Extragastrointestinal stromal tumor presenting as a scrotal mass: an unusual case.
We describe an unusual case of extragastrointestinal stromal tumor (EGIST) presenting as a scrotal mass. A 71-year-old man presented with a gradually enlarging scrotal mass with a 20-year duration. Physical examination revealed a huge (as large as volleyball), round, nontender mass occupying the whole scrotum, which was resected completely. Clinical and radiological findings did not comply with any other primary site disease. Under histological examination, the tumor showed a spindle cell pattern with low cellularity, absence of necrotic and mitotic features. immunohistochemical analysis revealed the tumor reactive for CD117 and CD34, while negative for smooth muscle actin, desmin and S-100 protein. To our knowledge, this is the first reported case of an EGIST involving the scrotum.
Kang
Seok-Ho
SH
Department of Urology, Korea University Hospital, Seoul 136-705, Korea.
Kim
Myung-Joon
MJ
Park
Min-Gu
MG
Park
Hong-Seok
HS
Moon
Du-Geon
DG
Sung
Deuk-Jae
DJ
Kim
Hyun-Chul
HC
Chae
Yang-Seok
YS
Cheon
Jun
J
Kim
Je-Jong
JJ
D000368:Aged; D018952:Antigens, CD34 / Q000032:analysis; D046152:Gastrointestinal Stromal Tumors / Q000175:diagnosis; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D019009:Proto-Oncogene Proteins c-kit / Q000032:analysis; D012611:Scrotum / Q000473:pathology*; D018312:Sex Cord-Gonadal Stromal Tumors / Q000737:chemistry / Q000473:pathology*
D018952:Antigens, CD34; D019009:Proto-Oncogene Proteins c-kit