[Micro-epidemic due to a new Mycobacterium tuberculosis strain among the homeless in Budapest, Hungary].
In a retrospective study that included 66 homeless tuberculosis patients a local micro-epidemic was identified in the VIIIth district of Budapest with the highest tuberculosis incidence of the capital. Further molecular genetic characterization by IS 6110 fingerprinting, spoligotyping and mycobacterial inter-spread repetitive unit (MIRU) typing has shown that the observed micro-epidemic was due to a locally emerged, Budapest-specific lineage. The absence of infections with the more virulent Beijing genotype is also noteworthy. The findings indicate that tuberculosis control and prevention steps among the homeless need to be strengthened in Hungary.
Ködmön
Csaba
C
ANTSZ Borsod-Abaúj-Zemplén Megyei Intézete Miskolc Meggyesalja 12, 3501. kodmoncs@borsod.antsz.hu
Lukács
Judit
J
Stefan
Niemann
N
Dávid
Sándor
S
Vadász
Imre
I
Somoskövy
Akos
A
D015373:Bacterial Typing Techniques / Q000379:methods; D016172:DNA Fingerprinting; D004269:DNA, Bacterial / Q000302:isolation & purification; D006703:Ill-Housed Persons / Q000706:statistics & numerical data*; D006801:Humans; D006814:Hungary / Q000453:epidemiology; D009169:Mycobacterium tuberculosis / Q000235:genetics*; D012189:Retrospective Studies; D014397:Tuberculosis, Pulmonary / Q000453:epidemiology* / Q000382:microbiology*
D004269:DNA, Bacterial