title: Performance evaluation of grid-enabled registration algorithms using bronze-standards.
abstract: Evaluating registration algorithms is difficult due to the lack of gold standard in most clinical procedures. The bronze standard is a real-data based statistical method providing an alternative registration reference through a computationally intensive image database registration procedure. We propose in this paper an efficient implementation of this method through a grid-interfaced workflow enactor enabling the concurrent processing of hundreds of image registrations in a couple of hours only. The performances of two different grid infrastructures were compared. We computed the accuracy of 4 different rigid registration algorithms on longitudinal MRI images of brain tumors. Results showed an average subvoxel accuracy of 0.4 mm and 0.15 degrees in rotation.
authors.affiliation: INRIA Sophia - Projet Asclepios, 2004 Route des Lucioles BP 93 06902 Sophia Antipolis Cedex, France. Xavier.Pennec@sophia.inria.fr
authors.forename: Tristan
authors.initials: T
authors.lastname: Glatard
authors.forename: Xavier
authors.initials: X
authors.lastname: Pennec
authors.forename: Johan
authors.initials: J
authors.lastname: Montagnat
mesh_terms: D000465:Algorithms; D001185:Artificial Intelligence; D001932:Brain Neoplasms / Q000473:pathology*; D005602:France; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D008279:Magnetic Resonance Imaging / Q000379:methods* / Q000592:standards; D010363:Pattern Recognition, Automated / Q000379:methods*; D012016:Reference Values; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013382:Subtraction Technique