title: Evaluation of a treatment manual for risperidone long-acting injectable.
abstract: We evaluated the usefulness of a treatment manual to facilitate the use of long-acting injectable risperidone in community mental health centers (CMHCs) during an open-label observational study. Perceived clinical utility and clinician adherence to the manual were evaluated. Patient adherence to treatment satisfaction, Clinical Global Impression of Severity (CGI-S) and the Schizophrenia Quality-of-Life Scale (SQLS) were assessed. Mean score for overall utility of the guidebook was 4.2 +/- .6 (scale ratings ranged from 1 = not at all to 5 = extremely). Most clinicians (89-100%) found the guidebook useful, and were adherent to key aspects of appropriate treatment use including concomitant oral risperidone use and injection and dosing parameters for long-acting risperidone. Most patients were adherent to treatment (86.7%), preferred long-acting risperidone over oral risperidone (72.6%) or other oral antipsychotics (78.4%) and were satisfied with long-acting risperidone (90.1%). The open-label observational design limits interpretation of these data. However, in this study manual-supported use of long-acting risperidone was associated with successful implementation of this pharmacologic treatment in the CMHC setting.
authors.affiliation: Comprehensive Neuroscience Inc., 21 Bloomingdale Road, White Plains, NY 10605, USA. jdocherty@cnsmail.com
authors.forename: John P
authors.initials: JP
authors.lastname: Docherty
authors.forename: Robert
authors.initials: R
authors.lastname: Jones
authors.forename: Ibrahim
authors.initials: I
authors.lastname: Turkoz
authors.forename: Robert A
authors.initials: RA
authors.lastname: Lasser
authors.forename: Mary
authors.initials: M
authors.lastname: Kujawa
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D014150:Antipsychotic Agents / Q000008:administration & dosage*; D005260:Female; D007722:Health Knowledge, Attitudes, Practice; D006801:Humans; D007267:Injections; D008297:Male; D008370:Manuals as Topic; D008875:Middle Aged; D011446:Prospective Studies; D018967:Risperidone / Q000008:administration & dosage* / Q000493:pharmacokinetics; D014481:United States
chemical_list: D014150:Antipsychotic Agents; D018967:Risperidone