Monoaminergic regulation of proliferation and differentiation of granulomonocytopoietic precursors during neuroses.
We studied the role of monoamines in the regulation of functional activity of granulocyte-macrophage precursors during neuroses. Under conditions of conflict situation and paradoxical sleep deprivation, monoamines of the central nervous system regulate proliferation and differentiation via alpha-adrenergic structures on granulomonocytopoietic precursors and cells of the hemopoiesis-inducing microenvironment.
Skurikhin
E G
EG
Institute of Pharmacology, Tomsk Research Center, Siberian Division of the Russian Academy of Medical Sciences.
Pershina
O V
OV
Minakova
M Yu
MY
Dygai
A M
AM
Gol'dberg
E D
ED
D000818:Animals; D015306:Biogenic Monoamines / Q000494:pharmacology*; D001854:Bone Marrow Cells / Q000166:cytology / Q000187:drug effects; D002454:Cell Differentiation / Q000187:drug effects* / Q000502:physiology; D049109:Cell Proliferation / Q000187:drug effects*; D002493:Central Nervous System Diseases / Q000503:physiopathology*; D003220:Conflict, Psychological; D015672:Erythroid Precursor Cells / Q000166:cytology* / Q000187:drug effects; D042381:Granulocyte Precursor Cells / Q000166:cytology* / Q000187:drug effects; D008297:Male; D051379:Mice; D008808:Mice, Inbred CBA; D012110:Reserpine / Q000494:pharmacology*; D012892:Sleep Deprivation / Q000503:physiopathology; D013234:Stem Cells; D013997:Time Factors
D015306:Biogenic Monoamines; D012110:Reserpine