title: [Cost analysis of tumor-induced osteolysis treated with intravenous zoledronic acid and pamidronate: a time-motion study].
abstract: A time-motion study was performed by evaluating time and use of medical supply resources in the administration of zoledronic acid and pamidronate as palliative care of tumor-induced osteolysis within the clinical setting of three Italian oncology day-hospital sites. The direct medical costs were similar for both treatments (Euro 226 for zoledronic acid versus Euro 231 for pamidronate). With the exclusion of the pharmacological therapy, most of the difference in costs derives from nurses' labor costs, which is related to the longer infusion time for pamidronate (1 h, 47 min versus 28 min for zoledronic acid).
authors.affiliation: Pbe Consulting, Verona. chiara.schivazappa@pbe.it
authors.forename: Chiara
authors.initials: C
authors.lastname: Schivazappa
authors.forename: Editta
authors.initials: E
authors.lastname: Baldini
authors.forename: Enrico
authors.initials: E
authors.lastname: Cortesi
authors.forename: Giuliana
authors.initials: G
authors.lastname: Dauria
authors.forename: Fausto
authors.initials: F
authors.lastname: Roila
authors.forename: Patrizia
authors.initials: P
authors.lastname: Berto
mesh_terms: D050071:Bone Density Conservation Agents / Q000008:administration & dosage* / Q000191:economics*; D003365:Costs and Cost Analysis; D004164:Diphosphonates / Q000008:administration & dosage* / Q000191:economics*; D006801:Humans; D007093:Imidazoles / Q000008:administration & dosage* / Q000191:economics*; D007262:Infusions, Intravenous; D009369:Neoplasms / Q000150:complications; D010014:Osteolysis / Q000188:drug therapy* / Q000191:economics* / Q000209:etiology; D000077268:Pamidronate; D013996:Time and Motion Studies; D000077211:Zoledronic Acid
chemical_list: D050071:Bone Density Conservation Agents; D004164:Diphosphonates; D007093:Imidazoles; D000077211:Zoledronic Acid; D000077268:Pamidronate