title: Diagnostic yield and impact of capsule endoscopy on management of patients with gastrointestinal bleeding of obscure origin.
abstract: This study assessed diagnostic yield and impact of capsule endoscopy on patient management. Seventy-five patients with obscure gastrointestinal bleeding were included. Clinical and followup information was collected by review of patient records and with personal contact with the referring physicians. All previous clinical information and interventions after capsule endoscopy and clinical outcome were noted. The indication was obscure-overt gastrointestinal bleeding in 36 patients (48%) and obscure-occult gastrointestinal bleeding in 39 patients (52%). Overall diagnostic yield was 66.7% considering relevant lesions. Followup was available in 31 patients. Capsule endoscopy changed clinical management in 61.4%. Multivariate analysis showed that patients with another potential source of bleeding and patients whose onset was hematochezia were not good candidates for capsule endoscopy. Capsule endoscopy has a high diagnostic yield and a positive influence on clinical management in a high proportion of patients with obscure gastrointestinal bleeding.
authors.affiliation: Sección de Aparato Digestivo, Unidad de Endoscopias, Hospital General, Virgen de la Luz, Cuenca, 16002, Spain. eredondoc@yahoo.es
authors.forename: Eduardo
authors.initials: E
authors.lastname: Redondo-Cerezo
authors.forename: Gracia
authors.initials: G
authors.lastname: Pérez-Vigara
authors.forename: Angel
authors.initials: A
authors.lastname: Pérez-Sola
authors.forename: Carmen J
authors.initials: CJ
authors.lastname: Gómez-Ruiz
authors.forename: Miriam Viñuelas
authors.initials: MV
authors.lastname: Chicano
authors.forename: Natividad
authors.initials: N
authors.lastname: Sánchez-Manjavacas
authors.forename: Julia
authors.initials: J
authors.lastname: Morillas
authors.forename: José I
authors.initials: JI
authors.lastname: Pérez-García
authors.forename: Jesús
authors.initials: J
authors.lastname: García-Cano
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D053704:Capsule Endoscopy; D005260:Female; D005500:Follow-Up Studies; D005767:Gastrointestinal Diseases / Q000150:complications / Q000175:diagnosis* / Q000628:therapy; D006471:Gastrointestinal Hemorrhage / Q000209:etiology*; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D009780:Occult Blood; D016017:Odds Ratio; D011237:Predictive Value of Tests; D012189:Retrospective Studies