Macro, micro and nano domains in the membrane of parasitic protozoa.
The structural organization of the plasma membrane of eukaryotic cells is briefly revised taking into consideration the organization of proteins and lipids and the concept of microdomains, lipid rafts and detergent resistant membranes. The biochemical data available concerning the presence of microdomains in parasitic protozoa is reviewed and emphasis is given on the identification of special domains recognized by morphological approaches, especially with the use of the freeze-fracture technique.
de Souza
Wanderley
W
Laboratório de Ultraestrutura Celular Hertha Meyer, Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, 21941-900, Rio de Janeiro, RJ, Brazil. wsouza@biof.ufrj.br
D000818:Animals; D002462:Cell Membrane / Q000737:chemistry* / Q000187:drug effects / Q000648:ultrastructure; D003902:Detergents / Q000494:pharmacology; D056890:Eukaryota / Q000737:chemistry / Q000648:ultrastructure*; D005614:Freeze Fracturing; D006801:Humans; D021962:Membrane Microdomains / Q000737:chemistry* / Q000648:ultrastructure; D008854:Microscopy, Electron
D003902:Detergents