STRA6, a cell-surface receptor for retinol-binding protein: the plot thickens.
How retinol (vitamin A) is taken up by cells has been an area of active research since the first report of a cell-surface receptor for retinol-binding protein (RBP) in the mid-1970s. Two recent reports, by Kawaguchi et al. (2007) and Pasutto et al. (2007), provide compelling data regarding the molecular identity and properties of a RBP receptor and open new research avenues for a better understanding of retinoid biology.
Blaner
William S
WS
Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA. wsb2@columbia.edu
D000818:Animals; D006801:Humans; D008565:Membrane Proteins / Q000235:genetics / Q000378:metabolism*; D012177:Retinol-Binding Proteins / Q000378:metabolism*; D014801:Vitamin A / Q000378:metabolism
D008565:Membrane Proteins; D012177:Retinol-Binding Proteins; C519685:STRA6 protein, human; C108001:Stra6 protein, mouse; D014801:Vitamin A