title: Antimicrobial and cytotoxic activities of Achyranthes ferruginea.
abstract: Chloroform extract (CE) of Achyranthes ferruginea and N-trans-feruloyl-4-methyldopamine (1) showed remarkable antimicrobial activities against a wide range of bacteria and fungi. Both crude extract (CE) and compound 1 showed significant cytotoxicity of LC(50) at 16.21 microg/ml and 11.70 microg/ml, respectively.
authors.affiliation: Phytochemistry Research Laboratories, Department of Pharmacy, University of Rajshahi, Rajshahi-6205, Bangladesh. mukhlesurrah@yahoo.co.uk
authors.forename: M Mukhlesur
authors.initials: MM
authors.lastname: Rahman
authors.forename: A H M Khurshid
authors.initials: AH
authors.lastname: Alam
authors.forename: Golam
authors.initials: G
authors.lastname: Sadik
authors.forename: M Robiul
authors.initials: MR
authors.lastname: Islam
authors.forename: Proma
authors.initials: P
authors.lastname: Khondkar
authors.forename: M Aslam
authors.initials: MA
authors.lastname: Hossain
authors.forename: Mohammad A
authors.initials: MA
authors.lastname: Rashid
mesh_terms: D029044:Achyranthes; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D000935:Antifungal Agents / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D006090:Gram-Negative Bacteria / Q000187:drug effects; D006094:Gram-Positive Bacteria / Q000187:drug effects; D006801:Humans; D008826:Microbial Sensitivity Tests; D003904:Mitosporic Fungi / Q000187:drug effects; D008517:Phytotherapy; D010936:Plant Extracts / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use
chemical_list: D000900:Anti-Bacterial Agents; D000935:Antifungal Agents; D010936:Plant Extracts