title: Black pigments in the liver related to gold and titanium deposits. A report of four cases.
abstract: Black pigments are rarely described in the liver. We report four patients with chronic cholestasis and black pigments described on liver histological examination. Energy-dispersive X-ray analysis identified these black pigments as gold particles in the first three patients and titanium particles in the fourth. The origin of the gold deposits was unknown in this first patient and related to gold salts therapy in the two others. Titanium deposits was associated with hepatic granulomas and related to total knee replacement.
authors.affiliation: Hepato-Gastroenterology, Hôpital St Joseph, Gilly, Belgium. r.brenard@hopitaux-gilly.be
authors.forename: R
authors.initials: R
authors.lastname: Brenard
authors.forename: P
authors.initials: P
authors.lastname: Dumortier
authors.forename: M
authors.initials: M
authors.lastname: Del Natale
authors.forename: B
authors.initials: B
authors.lastname: Honhon
authors.forename: M
authors.initials: M
authors.lastname: Van Den Berghe
authors.forename: C
authors.initials: C
authors.lastname: Bataille
authors.forename: F
authors.initials: F
authors.lastname: Rickaert
authors.forename: J
authors.initials: J
authors.lastname: Henrion
authors.forename: M O
authors.initials: MO
authors.lastname: Peny
authors.forename: J
authors.initials: J
authors.lastname: Rahier
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002779:Cholestasis / Q000000981:diagnostic imaging / Q000209:etiology / Q000473:pathology*; D002908:Chronic Disease; D005260:Female; D006046:Gold / Q000032:analysis*; D006801:Humans; D008099:Liver / Q000737:chemistry* / Q000000981:diagnostic imaging / Q000473:pathology; D008264:Macrophages / Q000737:chemistry; D008297:Male; D008875:Middle Aged; D011859:Radiography; D014025:Titanium / Q000032:analysis*
chemical_list: D006046:Gold; D014025:Titanium