Effects of synthetic conjugated estrogens A on sleep quality in postmenopausal women with nocturnal diaphoresis and/or hot flushes: a pilot study.
In a single-center, double-blind, placebo-controlled pilot study, patients who received 0.625 mg daily of synthetic conjugated estrogens A experienced a statistically significant reduction in the average number of hot flushes and galvanic skin responses. The polysomnographic change in sleep measures did not reach statistical significance, but the data suggest an overall improvement in sleep quality in the treatment group.
Scharf
Martin B
MB
Tri-State Sleep Disorders Center, The Center for Research in Sleep Disorders, Cincinnati, Ohio, USA.
Berkowitz
David V
DV
Reape
Kathleen Z
KZ
D004311:Double-Blind Method; D004966:Estrogens, Conjugated (USP) / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D010865:Pilot Projects; D010919:Placebos; D017286:Polysomnography; D017698:Postmenopause; D012890:Sleep / Q000187:drug effects / Q000502:physiology*; D012893:Sleep Wake Disorders / Q000188:drug therapy*
D004966:Estrogens, Conjugated (USP); D010919:Placebos