Assessment of airway remodeling in asthma: volumetric versus surface quantification approaches.
This paper develops a volumetric quantification approach of the airway wall in multi-detector computed tomography (MDCT), exploiting a 3D segmentation methodology based on patient-specific deformable mesh model. A comparative study carried out with respect to a reference 2D/3D surface quantification technique underlines the clinical interest of the proposed approach in assessing airway remodeling in asthmatics and in evaluating the efficiency of therapeutic protocols.
Saragaglia
Amaury
A
ARTEMIS Project Unit, INT, Groupe des Ecoles des Télécommunications, Evry Cedex, France.
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D000465:Algorithms; D001249:Asthma / Q000000981:diagnostic imaging*; D001995:Bronchography / Q000379:methods*; D006801:Humans; D021621:Imaging, Three-Dimensional / Q000379:methods*; D011856:Radiographic Image Enhancement / Q000379:methods*; D011857:Radiographic Image Interpretation, Computer-Assisted / Q000379:methods*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013499:Surface Properties; D013990:Tidal Volume; D014057:Tomography, X-Ray Computed / Q000379:methods*