Etomidate for rapid sequence intubation in the emergency department: is adrenal suppression a concern?
Etomidate has become one of the most commonly used induction agents in the United States during emergency department (ED) endotracheal intubation. While etomidate may be popular, concerns have been raised about possible adrenal suppression and subsequent adverse effects. In this paper we critically evaluate the recent literature and perspectives regarding the effect of etomidate on the adrenocortical system.
Zed
Peter J
PJ
CSU Pharmaceutical Sciences, Vancouver General Hospital, Vancouver, British Columbia, Canada.
Mabasa
Vincent H
VH
Slavik
Richard S
RS
Abu-Laban
Riyad B
RB
D000309:Adrenal Insufficiency / Q000139:chemically induced*; D004636:Emergency Service, Hospital; D005045:Etomidate / Q000008:administration & dosage* / Q000009:adverse effects*; D006801:Humans; D006993:Hypnotics and Sedatives / Q000008:administration & dosage* / Q000009:adverse effects*; D007442:Intubation, Intratracheal
D006993:Hypnotics and Sedatives; D005045:Etomidate