The active platelet: translation and protein synthesis in an anucleate cell.
Platelets are the major cellular component of the hemostatic system that controls vessel and wound repair. However, platelets also have a variety of additional functions in inflammatory responses and host defense. The function and structure of the platelet was assumed to be very simple for a long period of time. With more modern tools of investigation such as cDNA arrays and proteomics, we have discovered a cell that is becoming a more sophisticated libero that functions in the classic mechanisms of white blood cells--inflammation and immunity.
Lindemann
Stephan
S
Medizinische Klinik III, Eberhard Karls-Universität Tübingen, Tübingen, Germany. stephan.lindemann@med.uni-tuebingen.de
Gawaz
Meinrad
M
D000818:Animals; D001792:Blood Platelets / Q000276:immunology / Q000378:metabolism* / Q000502:physiology; D006801:Humans; D015539:Platelet Activation; D014176:Protein Biosynthesis; D040901:Proteomics