Scan patterns during the processing of facial identity in prosopagnosia.
The scan patterns of ocular fixations made by prosopagnosic patients while they attempt to identify faces may provide insights into how they process the information in faces. Contrasts between their scanning of upright versus inverted faces may index the presence of a hypothesized orientation-dependent expert mechanism for processing faces, while contrasts between their scanning of familiar versus novel faces may index the influence of residual facial memories on their search for meaningful facial information. We recorded the eye movements of two prosopagnosics while they viewed faces. One patient, with acquired prosopagnosia from a right occipitotemporal lesion, showed degraded orientation effects but still with a normal distribution of fixations to more salient facial features. However, the dynamics of his global scan patterns were more chaotic for novel faces, suggesting degradation of an internal facial schema, and consistent with other evidence of impaired face configuration perception in this patient. His global scan patterns for famous faces differed from novel faces, suggesting the influence of residual facial memories, as indexed previously by his relatively good imagery for famous faces. The other patient, with a developmental prosopagnosia, showed anomalous orientation effects, abnormal distribution of fixations to less salient regions, and chaotic global scan patterns, in keeping with a more severe loss of face-expert mechanisms. The effects of fame on her scanning were weaker than those in the first subject and non-existent in her global scan patterns. We conclude that scan patterns in prosopagnosia can both reflect the loss of orientation-dependent expert mechanisms and index the covert influence of residual facial memories. In these two subjects the scanning data were consistent with other results from tests of configuration perception, imagery, and covert recognition.
Barton
Jason J S
JJ
Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
Radcliffe
Nathan
N
Cherkasova
Mariya V
MV
Edelman
Jay A
JA
D000328:Adult; D001921:Brain / Q000473:pathology; D001932:Brain Neoplasms / Q000150:complications / Q000601:surgery; D002543:Cerebral Hemorrhage / Q000209:etiology / Q000523:psychology; D003627:Data Interpretation, Statistical; D004829:Epilepsy, Generalized / Q000523:psychology; D005133:Eye Movements / Q000502:physiology; D005145:Face; D005260:Female; D005403:Fixation, Ocular; D007839:Functional Laterality / Q000502:physiology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008390:Markov Chains; D008568:Memory / Q000502:physiology; D008875:Middle Aged; D009483:Neuropsychological Tests; D009837:Oligodendroglioma / Q000150:complications / Q000601:surgery; D009949:Orientation / Q000502:physiology; D020238:Prosopagnosia / Q000503:physiopathology* / Q000523:psychology*; D011597:Psychomotor Performance / Q000502:physiology; D021641:Recognition, Psychology / Q000502:physiology*; D014796:Visual Perception / Q000502:physiology