Galactosaminoglycan function and oligosaccharide structure determination.
This review will discuss the importance of sequencing long chondroitin sulfate and dermatan sulfate chains specifically derived from decorin. Decorin is a member of the small leucine-rich repeat proteoglycans and ubiquitously expressed primarily in the skin. Sequence information and diverse function of glycosaminoglycans is further influenced by variable expression through the core protein indicating the importance to analyse glycosaminoglycans from specific proteoglycans.
Seidler
Daniela G
DG
Department of Physiological Chemistry and Pathobiochemistry, UKM, University of Münster, D-48149, Münster, Germany. dgseidle@uni-muenster.de
Peter-Katalinić
Jasna
J
Zamfir
Alina D
AD
D002240:Carbohydrate Sequence; D002809:Chondroitin Sulfates / Q000737:chemistry* / Q000648:ultrastructure*; D003198:Computer Simulation; D003871:Dermatan Sulfate / Q000737:chemistry* / Q000648:ultrastructure*; D006801:Humans; D008956:Models, Chemical; D008958:Models, Molecular; D008969:Molecular Sequence Data; D017421:Sequence Analysis; D012867:Skin / Q000737:chemistry*
D003871:Dermatan Sulfate; D002809:Chondroitin Sulfates