title: Microwave assisted synthesis of triazoloquinazolinones and benzimidazoquinazolinones.
abstract: BACKGROUND
  Benzimidazoquinazolinones and related quinazolines are classes of heterocycles that are of considerable interest because of the diverse range of their biological properties. Although numerous classes of quinazolines have been conventionally synthesized, their syntheses have been suffered due to the multiple steps that sometimes have described in their preparation and also their chemical transformations that have been taken hours or even days to be completed. However, microwave energy can offer numerous benefits for performing synthesis of organic compounds including reduced pollution, increased reaction rates, yield enhancements, and cleaner chemistries.
  
  
  RESULTS
  Synthesis of a series of triazoloquinazolinones and benzimidazoquinazolinones has been achieved under microwave irradiation. The products were obtained in nearly quantitative yields within few minutes during the reaction of aromatic aldehydes with 5-amino-1(H)-1,2,4-triazole (or 2-aminobenzimidazole) and dimedone in DMF.
  
  
  CONCLUSIONS
  Microwave irradiation can be used as a facile and general method for the construction of a wide variety of triazoloquinazolinones and benzimidazoquinazolinones. The reaction involves a three component condensation (with potential for combinatorial work) being carried out with almost productive yields by microwave irradiation and considerably shortened reaction time.
authors.affiliation: Chemistry Department, Faculty of Science, El-Minia University, 61519-El-Minia, Egypt. mourad_aboulf@yahoo.com
authors.forename: Aboul-Fetouh E
authors.initials: AF
authors.lastname: Mourad
authors.forename: Ashraf A
authors.initials: AA
authors.lastname: Aly
authors.forename: Hassan H
authors.initials: HH
authors.lastname: Farag
authors.forename: Eman A
authors.initials: EA
authors.lastname: Beshr