title: Seminoma in a male phenotype 46XX true hermaphrodite.
abstract: Although true hermaphrodite is uncommon, it has been reported in more than 400 individuals. Tumours arising in the gonads of true hermaphrodite is a very rare finding and only very few cases have been reported in the literature. We report a case of a 35-year-old phenotype man with bilateral undescended testis with lump hypogastrium. On examination, he had an ovotestis on one side and pure seminoma arising in testis on the other side. The seminoma arising in the left undescended testis was successfully treated by excision and combination chemotherapy. Cytogenetic studies revealed that 46XX karyotype with primer specific for the sex-determining region of the Y chromosome was negative. The karyotypic abnormality noticed in the patient is also reviewed in the article.
authors.affiliation: Department of Surgery, PGIMS, Rohtak (Haryana), India. drrvmalik@yahoo.co.in
authors.forename: Vinod
authors.initials: V
authors.lastname: Malik
authors.forename: Dinesh
authors.initials: D
authors.lastname: Gupta
authors.forename: Meenu
authors.initials: M
authors.lastname: Gill
authors.forename: Amba Lal
authors.initials: AL
authors.lastname: Salvi
mesh_terms: D000328:Adult; D006801:Humans; D008297:Male; D050090:Ovotesticular Disorders of Sex Development / Q000150:complications* / Q000473:pathology / Q000628:therapy; D018239:Seminoma / Q000150:complications* / Q000628:therapy; D013736:Testicular Neoplasms / Q000150:complications* / Q000601:surgery