title: Management of acid- and alkali-induced esophageal strictures in 79 adults by endoscopic dilation: 8-years' experience in New Delhi.
abstract: Experience with endoscopic dilation of acid- and alkali-induced strictures of the esophagus using Savary-Gilliard (SG) and balloon dilators is limited, especially in adults. The aim of this study was to determine the safety and efficacy of endoscopic dilation in the management of corrosive esophageal strictures and to compare results with regard to acid- vs. alkali-induced strictures. The records of 230 patients who were treated by endoscopic dilation between 1997 and 2005 at our center were reviewed. This study included all the patients who had corrosive-induced esophageal strictures. SG dilators were used in most of our patients [67/79 (85%)], while only a few patients [12/79 (15%)] were treated with balloon dilators. Dilation was found to be successful after an initial course of dilation (not requiring further dilations) in 28/37 (75.67%) cases in the SG dilator group and in 9/12 (75%) in the balloon group. Strictures caused by acids required a greater mean number of dilations for initial relief of dysphagia compared with that for alkalis. Some of these patients responded to a second course of dilation, leading to final combined SG dilator and balloon dilator success rates of 24/28 (86%) in the acid group and 17/21 (81%) in the alkali group. A total of 359 sessions of dilations were performed with a complication rate of 2/359 (0.56%). Endoscopic dilation using Savary-Gilliard and balloon dilators is safe and effective in managing corrosive esophageal strictures, but it is operator-dependent and the final outcome depends largely on the technical expertise and appropriate selection of patients.
authors.affiliation: Gastroenterology Division, Department of Medicine, Maulana Azad Medical College and Lok Nayak Hospital, New Delhi, India.
authors.forename: Shashideep
authors.initials: S
authors.lastname: Singhal
authors.forename: Premashis
authors.initials: P
authors.lastname: Kar
mesh_terms: D000328:Adult; D000468:Alkalies; D002404:Catheterization; D003343:Corrosion; D003679:Deglutition; D003680:Deglutition Disorders / Q000473:pathology*; D016099:Endoscopy, Gastrointestinal; D004940:Esophageal Stenosis / Q000628:therapy*; D005260:Female; D005744:Gastric Acid; D006801:Humans; D007194:India; D008297:Male
chemical_list: D000468:Alkalies