Primary signet-ring cell carcinoma of the prostate.
We report on an uncommon case of primary prostatic signet-ring cell carcinoma (SRCC) in a 78-year-old man. His prostatic specific antigen (PSA) level at presentation was 9.8 ng/ml. Histologically the tumor had a signet-ring morphology. Detailed immunohistochemical studies confirmed the prostatic origin of this neoplasm. All mucin stains were negative. This aggressive tumor is a distinct variant of primary prostatic carcinoma which should be distinguished from artefactual vacuolation of the tumor and metastatic disease.
Klimis
T
T
Department of Pathology, 3rd Hospital of Social Security Foundation, Athens, Greece.
Margaritopoulou
A
A
Vlahos
P
P
Kokotas
N
N