title: [Development of research on liver stem cell and its future application].
abstract: OBJECTIVE
  To investigate the research development of the liver stem cell (LSC) and to predict its future application.
  
  
  METHODS
  Based on our own researches and combined with the review of the related literature at home and abroad, we analyzed and evaluated the latest development of the research on the LSC.
  
  
  RESULTS
  We knew the differentiation and proliferation of the LSC towards some kinds of specified cells were affected by many factors; and the researches on the LSC in regard to its activation, isolating culture, bolting, and evaluation still needed further improvements.
  
  
  CONCLUSIONS
  With the development of the research, the liver stem cell can become a new seed cell to cure some liver diseases.
authors.affiliation: Department of General Surgery, West China Hospital, Sichuan University, Chengdu Sichuan, 610041, P. R. China. lfg1616@163.com
authors.forename: Fugui
authors.initials: F
authors.lastname: Li
authors.forename: Lvnan
authors.initials: L
authors.lastname: Yan
mesh_terms: D000818:Animals; D001854:Bone Marrow Cells / Q000166:cytology; D018929:Cell Culture Techniques; D002454:Cell Differentiation; D049109:Cell Proliferation; D002469:Cell Separation / Q000379:methods; D002478:Cells, Cultured; D053595:Embryonic Stem Cells / Q000166:cytology; D022781:Hepatocytes / Q000166:cytology*; D006801:Humans; D008107:Liver Diseases / Q000628:therapy*; D008113:Liver Neoplasms / Q000628:therapy; D051379:Mice; D033581:Stem Cell Transplantation; D013234:Stem Cells / Q000166:cytology*; D023822:Tissue Engineering