Cutaneous leishmaniasis.
Cutaneous leishmaniasis is a widespread tropical infection caused by numerous different species of Leishmania protozoa that are transmitted by sandflies. Its clinical presentations are extremely diverse and dependent on a variety of parasite and host factors that are poorly understood. Diagnosis should aim to identify the exact species involved, but this requires laboratory investigations that are not widely available. No single ideal treatment has been identified, and those available are limited by variable success rates and toxicity. Clinical guidelines are needed to make better use of the investigations and treatments that do exist. Prevention is currently limited to bite prevention measures.
Bailey
Mark S
MS
Army Medical Directorate, Camberley GU15 4NP, UK.
Lockwood
Diana N J
DN
D000563:Amebicides / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use; D000967:Antimony Sodium Gluconate / Q000627:therapeutic use; D000981:Antiprotozoal Agents / Q000627:therapeutic use; D001558:Benzethonium / Q000031:analogs & derivatives / Q000627:therapeutic use; D017679:Cryotherapy; D003475:Curettage; D003937:Diagnosis, Differential; D006801:Humans; D006979:Hyperthermia, Induced; D016773:Leishmaniasis, Cutaneous / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy; D010303:Paromomycin / Q000627:therapeutic use
D000563:Amebicides; D000935:Antifungal Agents; D000981:Antiprotozoal Agents; D001558:Benzethonium; D010303:Paromomycin; D000967:Antimony Sodium Gluconate; C005106:methylbenzethonium chloride