title: One-day surgery for acquired forefoot deformity: sciatic nerve blockade with mepivacaine vs mepivacaine+ropivacaine: a prospective, randomized study.
abstract: OBJECTIVE
  The aim of the study was to determine the doses of ropivacaine combined with mepivacaine for sciatic nerve blockade to enable the extension of analgesia without prolonged motor blockade, for the management of very painful operations in one-day surgery.
  
  
  METHODS
  After obtaining approval by the ethics committee and written informed consent, we recruited 30 ASA I-III patients undergoing corrective orthopedic surgery of the forefoot in one-day surgery with sciatic nerve blockade. The patients were randomly divided into 3 groups: one control group, treated by 1.5% mepivacaine (300 mg), and two groups differentiated by the dose of 0.5% ropivacaine (25 and 40 mg) used in combination with 1.5% mepivacaine (225 mg). The offset data of the blockade were obtained by a self-assessment form filled in by the patients, and a direct check on discharge by a blinded observer.
  
  
  RESULTS
  There was no significant difference in the duration of the blockade among the 3 groups; the extension of analgesia was significant (P<0.003) in the group treated by mepivacaine+ropivacaine 40 mg (mean 477+/-255 min).
  
  
  CONCLUSIONS
  Adequate doses of ropivacaine added to mepivacaine for peripheral blockade produce and increase the duration of analgesia without influencing the criteria for discharge after Day Surgery.
authors.affiliation: Department of Anesthesiology, and Intensive Care IRCCS Istituti Ortopedici Rizzoli, Bologna, Italy. s.bugamelli@libero.it
authors.forename: S
authors.initials: S
authors.lastname: Bugamelli
authors.forename: E
authors.initials: E
authors.lastname: Zangheri
authors.forename: M
authors.initials: M
authors.lastname: Montebugnoli
authors.forename: B
authors.initials: B
authors.lastname: Borghi
authors.forename: A
authors.initials: A
authors.lastname: Ricci
authors.forename: N
authors.initials: N
authors.lastname: De Simone
authors.forename: M
authors.initials: M
authors.lastname: Bonfatti
authors.forename: K
authors.initials: K
authors.lastname: Elmar
authors.forename: M
authors.initials: M
authors.lastname: Luppi
authors.forename: E
authors.initials: E
authors.lastname: Pignotti
mesh_terms: D000328:Adult; D000556:Ambulatory Surgical Procedures; D000577:Amides; D000779:Anesthetics, Local; D005260:Female; D005528:Foot / Q000601:surgery*; D006801:Humans; D008297:Male; D008619:Mepivacaine; D008875:Middle Aged; D009407:Nerve Block; D019637:Orthopedic Procedures; D011446:Prospective Studies; D000077212:Ropivacaine; D012584:Sciatic Nerve
chemical_list: D000577:Amides; D000779:Anesthetics, Local; D000077212:Ropivacaine; D008619:Mepivacaine