title: [MIC and MBC of quinupristin/dalfopristin of erythromycin-resistant MRSA strains isolated from clinical specimens].
abstract: The MICs and MBCs of quinupristin/dalfopristin were determined for 22 clinical strains MRSA with inducible type of resistance to MLS-B and for 15 of their derivatives with constitutive resistance to MLS-B. For MRSA strains with inducible resistance to MLS-B the obtained results for quinupristin/ dalfopristin were: MIC50 = 0.25, MIC90 = 0.5, MBC50 = 1.0 and MBC90 = 1.0. Mutants of the same strains characterized with the following values for quinopristin/dalfopristin: MIC50 = 0.5, MIC90 = 1.5, MBC50 = 4.0 and MTC90 = 8.0.
authors.affiliation: Katedra i Zakład Mikrobiologii Lekarskiej AM w Warszawie.
authors.forename: Grazyna
authors.initials: G
authors.lastname: Młynarczyk
authors.forename: Andrzej
authors.initials: A
authors.lastname: Młynarczyk
authors.forename: Ksenia
authors.initials: K
authors.lastname: Szymanek
authors.forename: Agata
authors.initials: A
authors.lastname: Bilewska
authors.forename: Julia
authors.initials: J
authors.lastname: Pupek
authors.forename: Mirosław
authors.initials: M
authors.lastname: Luczak
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology; D024901:Drug Resistance, Multiple, Bacterial; D004917:Erythromycin / Q000494:pharmacology*; D006801:Humans; D020128:Inhibitory Concentration 50; D016106:Methicillin Resistance; D008826:Microbial Sensitivity Tests; D013045:Species Specificity; D013211:Staphylococcus aureus / Q000145:classification / Q000187:drug effects* / Q000302:isolation & purification; D014769:Virginiamycin / Q000494:pharmacology*
chemical_list: D000900:Anti-Bacterial Agents; D014769:Virginiamycin; C062940:quinupristin-dalfopristin; D004917:Erythromycin