[Correlation between syndromes of posthepatitic cirrhosis and biological parameters: a report of 355 cases].
OBJECTIVE
To investigate the pathological factors of syndrome pathomechanism through studying the correlation between syndromes of posthepatitic cirrhosis and biological parameters.


METHODS
Clinical information of three hundred and fifty-five patients with posthepatitic cirrhosis was collected and the database was established. Parameters with statistical significance were analyzed with multi-factor regression analysis to investigate the main influencing factors of the syndromes of posthepatitic cirrhosis.


RESULTS
Formulae of six syndromes, including syndrome of yin deficiency of liver and kidney, syndrome of damp heat, syndrome of stagnated heat smoldering, syndrome of yang deficiency of spleen and kidney, syndrome of stagnation of liver qi and spleen deficiency and syndrome of blood stasis due to qi deficiency, were established with stepwise regression analysis.


CONCLUSIONS
One of the pathophysiological bases of syndrome of blood stasis due to qi deficiency in cirrhosis is synthetic dysfunction of hepatocytes. The pathophysiological basis of syndrome of damp heat is inflammatory injury, which is also syndrome of stagnated heat smoldering in cirrhosis patients. The relationship between syndrome of yin deficiency of liver and kidney and stasis and damp heat may be the pathophysiological basis of the posthepatitic cirrhosis..
Zhang
Qin
Q
Shanghai Public Health Clinical Center, Fudan University, Shanghai 201508, China.
Qiu
Hong
H
Wang
Lei
L
DU
Guang-li
GL
Liu
Ping
P
D000293:Adolescent; D000328:Adult; D000368:Aged; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008103:Liver Cirrhosis / Q000097:blood / Q000175:diagnosis*; D008297:Male; D008516:Medicine, Chinese Traditional / Q000379:methods*; D008875:Middle Aged; D019413:Qi; D012044:Regression Analysis; D013577:Syndrome; D016711:Yang Deficiency / Q000097:blood / Q000175:diagnosis; D016710:Yin Deficiency / Q000097:blood / Q000175:diagnosis