title: [Bilateral optic nerve infiltration in acute lymphoblastic leukemia in remission].
abstract: METHODS
  An 18-year-old male affected by acute lymphoblastic leukemia (ALL) after having reached complete remission after chemotherapy developed bilateral optic nerve infiltration.
  
  
  CONCLUSIONS
  Infiltration of the optic nerve may appear as an isolated sign of extramedullary relapse of ALL months in advance of the hematologic relapse.
authors.affiliation: Hospital Clínico Universitario Lozano Blesa, Zaragoza, España. jmateo1999@yahoo.es
authors.forename: J
authors.initials: J
authors.lastname: Mateo
authors.forename: R
authors.initials: R
authors.lastname: Abarzuza
authors.forename: E
authors.initials: E
authors.lastname: Núñez
authors.forename: J A
authors.initials: JA
authors.lastname: Cristóbal
mesh_terms: D000293:Adolescent; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D005654:Fundus Oculi; D006801:Humans; D017254:Leukemic Infiltration; D008297:Male; D009900:Optic Nerve / Q000473:pathology*; D010211:Papilledema / Q000175:diagnosis; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000188:drug therapy / Q000401:mortality / Q000473:pathology*; D011379:Prognosis; D012008:Recurrence; D012074:Remission Induction