[Prevalence of hepatitis G virus infection (HGV) in intravenous immunoglobulin recipients in the Czech Republic].
The prevalence of hepatitis G virus (HGV) in the serum of intravenous immunoglobulin (IVIG) recipients was studied and risk related to HGV positivity was considered. Although its pathogenicity is unclear, HGV is likely to cause liver disease or lymphoproliferation. Twenty (23%) of 86 tested MG patients were HGV RNA positive. Of the HGV positive patients, three (15%) showed mild elevation of liver enzymes and one (5%) was diagnosed with chronic lymphatic leukaemia prior to the institution of MG replacement. It can be concluded that the HGV prevalence among IVIG recipients is high but is not associated with signs of either liver disease or lymphoproliferation.
Sobotková
M
M
Ustav imunologie UK 2.LF a FN Motol, Praha. marta.sobotkova@fnmotol.cz
Bartůnková
J
J
Litzman
J
J
Zachová
R
R
Jílek
D
D
Krystůfková
O
O
Nĕmecek
V
V
Vernerová
E
E
Sedivá
A
A
D018153:Czech Republic / Q000453:epidemiology; D029407:GB virus C / Q000302:isolation & purification*; D006525:Hepatitis, Viral, Human / Q000175:diagnosis* / Q000453:epidemiology / Q000821:virology; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000009:adverse effects / Q000627:therapeutic use*; D007153:Immunologic Deficiency Syndromes / Q000188:drug therapy; D015995:Prevalence; D012698:Serologic Tests
D016756:Immunoglobulins, Intravenous