Placing pain on the sensory map: classic papers by Ed Perl and colleagues.
This essay looks at two papers published by Ed Perl and co-workers that identified specifically nociceptive neurons in the periphery and superficial dorsal horn. Bessou P and Perl ER. Response of cutaneous sensory units with unmyelinated fibers to noxious stimuli. J Neurophysiol 32: 1025-1043 1969. Christensen BN and Perl ER. Spinal neurons specifically excited by noxious or thermal stimuli: marginal zone of the dorsal horn. J Neurophysiol 33: 293-307 1970.
Mason
Peggy
P
Department of Neurobiology, Pharmacology and Physiology, Committee on Neurobiology, University of Chicago, Chicago, Illinois, USA. p-mason@uchicago.edu
D000344:Afferent Pathways / Q000502:physiology*; D049672:History, 19th Century; D049673:History, 20th Century; D006801:Humans; D009412:Nerve Fibers / Q000502:physiology; D009619:Nociceptors / Q000502:physiology*; D010146:Pain / Q000266:history / Q000473:pathology / Q000503:physiopathology*