title: Subgingival chlorhexidine varnish administration as an adjunct to same-day full-mouth root planing. I. Clinical observations.
abstract: BACKGROUND
  Chemo-mechanical treatment concepts have been developed to improve the outcome of non-surgical periodontal therapy. Recently, the clinical additive value of a supersaturated chlorhexidine varnish was shown when used as an adjunct to staged scaling and root planing. The aim of this study was to investigate the clinical effects of a treatment strategy for chronic periodontitis based on a combination of same-day full-mouth root planing and subgingival chlorhexidine varnish administration.
  
  
  METHODS
  A randomized, controlled, single-blind, parallel trial was conducted on 33 non-smoking chronic periodontitis patients. The control group received oral hygiene instructions and same-day full-mouth root planing. The test group received the same instructions and treatment; however, all pockets were disinfected using a chlorhexidine varnish. Clinical response parameters were recorded at baseline and after 1, 3, and 6 months.
  
  
  RESULTS
  Both groups showed significant reductions in probing depth following therapy (P <0.001). There was no significant difference in full-mouth probing depth between the groups at any examination point. However, when a site-specific comparison was made, additive effects were found in the test group; an extra pocket reduction of 0.93 mm (P = 0.044) for initially deep pockets (>or=7 mm) was found at study termination. Additive clinical attachment gains seemed to be temporary. Impermanent extra pocket reductions and clinical attachment gains were found for initially medium-deep pockets (4 to 6 mm).
  
  
  CONCLUSIONS
  The outcome of same-day full-mouth root planing may benefit from the subgingival administration of a highly concentrated chlorhexidine varnish, at least in terms of pocket reduction in initially deep sites (>or=7 mm).
authors.affiliation: Department of Periodontology, School of Dental Medicine, Free University of Brussels, Brussels, Belgium. jan.cosyn@vub.ac.be
authors.forename: Jan
authors.initials: J
authors.lastname: Cosyn
authors.forename: Iris
authors.initials: I
authors.lastname: Wyn
authors.forename: Tim
authors.initials: T
authors.lastname: De Rouck
authors.forename: Mehran Moradi
authors.initials: MM
authors.lastname: Sabzevar
mesh_terms: D000891:Anti-Infective Agents, Local / Q000008:administration & dosage*; D002710:Chlorhexidine / Q000008:administration & dosage / Q000031:analogs & derivatives*; D002908:Chronic Disease; D003131:Combined Modality Therapy; D003774:Dental Plaque Index; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010150:Paint; D010512:Periodontal Index; D010518:Periodontitis / Q000628:therapy*; D016745:Root Planing; D016037:Single-Blind Method
chemical_list: D000891:Anti-Infective Agents, Local; C010882:chlorhexidine gluconate; D002710:Chlorhexidine