Stroke and migraine.
Young patients with migraine are at increased risk for stroke, particularly patients with an aura of focal neurologic deficits. Other causes of ischemia are often identified in patients with migraine, including patent foramen ovale, lupus anticoagulant, cervical carotid dissection, arteriovenous malformation, and hyperactivity of the clotting system. Migrainous stroke is only diagnosed when all other possible causes of stroke have been eliminated and the patient has irreversibility of the usual aura, associated with an ischemic infarct in the appropriate brain territory. Prophylactic therapy of migraine with aura may be beneficial in preventing migrainous stroke.
Weinberger
Jesse
J
Department of Neurology, Box 1052, The Mount Sinai School of Medicine, 1 Gustave Levy Place, New York, NY 10029, USA. jesse.weinberger@mssm.edu
D001158:Arteries / Q000002:abnormalities; D001777:Blood Coagulation; D001921:Brain / Q000098:blood supply; D002545:Brain Ischemia / Q000150:complications; D002560:Cerebrovascular Circulation; D006344:Heart Septal Defects, Atrial / Q000150:complications; D006801:Humans; D008881:Migraine Disorders / Q000097:blood / Q000150:complications* / Q000453:epidemiology / Q000503:physiopathology / Q000628:therapy; D012307:Risk Factors; D020521:Stroke / Q000097:blood / Q000453:epidemiology / Q000209:etiology* / Q000503:physiopathology / Q000628:therapy