title: [Endocrine disorders and the heart].
abstract: Hormonal regulation is not possible without the cardiovascular system, and thus the heart plays a special role not only in the action and synthesis, but also in the distribution of hormones. Severe endocrine disorders with cardiac involvement are often threatening for the patient. The impact of aberrant thyroid function, the sympathetic-adrenal symptoms of which predominantly affect the heart, is well known. Diabetes mellitus and the associated metabolic syndrome are major causes of cardiovascular disease and determine its morbidity and lethality rates. Acromegaly causes a complex cardiomyopathy that may result in cardiac failure refractive to conventional treatment. The excessive production of adrenal hormones in Cushing's syndrome, hyperaldosteronism and pheochromocytoma primarily harms the heart by causing severe hypertension. The same holds true for long-standing hyperparathyroidism. Recent prospective studies did not confirm the protective effect of hormone replacement therapy on cardiovascular disease.
authors.affiliation: Klinik für Endokrinologie, Zentrum für Innere Medizin, Universitätsklinikum Essen, Universität Duisburg-Essen, Hufelandstrasse 55, 45122 Essen, Deutschland. onno.janssen@uni-due.de
authors.forename: Onno E
authors.initials: OE
authors.lastname: Janssen
authors.forename: K
authors.initials: K
authors.lastname: Mann
authors.forename: R
authors.initials: R
authors.lastname: Erbel
mesh_terms: D000328:Adult; D001145:Arrhythmias, Cardiac / Q000175:diagnosis / Q000209:etiology; D009202:Cardiomyopathies / Q000175:diagnosis / Q000209:etiology; D002648:Child; D003327:Coronary Disease / Q000175:diagnosis / Q000209:etiology; D004700:Endocrine System Diseases / Q000150:complications* / Q000175:diagnosis; D006331:Heart Diseases / Q000175:diagnosis / Q000209:etiology*; D006333:Heart Failure / Q000175:diagnosis / Q000209:etiology; D006801:Humans; D006973:Hypertension / Q000175:diagnosis / Q000209:etiology; D017379:Hypertrophy, Left Ventricular / Q000175:diagnosis / Q000209:etiology; D012307:Risk Factors