[Study on interaction between hypocrellin A and hemoglobin or myoglobin using synchronous fluorescence spectra].
The effects of hypocrellin A (HA) on the conformational changes of hemoglobin and myoglobin were studied using synchronous fluorescence spectroscopy. The results indicated that HA can change the conformation of these two proteins, leading to the change in the micro-environment of tryptophane and tyrosine residues from hydrophobic environment to hydrophilic environment to different extent.
Wu
Xiao-hong
XH
Analysis and Testing Center, Nanjing Normal University, Jiangsu Engineering Research Center of Bio-Medical Function Materials, Nanjing 210097, China.
Zhou
Jia-hong
JH
Gu
Xiao-tian
XT
Wei
Shao-hua
SH
Feng
Yu-ying
YY
Lu
Tian-hong
TH
Wang
Xue-song'
XS
Zhang
Bao-wen
BW
D006454:Hemoglobins / Q000737:chemistry*; D015394:Molecular Structure; D009211:Myoglobin / Q000737:chemistry*; D010569:Perylene / Q000031:analogs & derivatives* / Q000737:chemistry; D019800:Phenol; D011809:Quinones / Q000737:chemistry*; D013050:Spectrometry, Fluorescence
D006454:Hemoglobins; D009211:Myoglobin; D011809:Quinones; D019800:Phenol; D010569:Perylene; C048388:hypocrellin A