A case of Lhermitte-Duclos disease presenting high FDG uptake on FDG-PET/CT.
Lhermitte-Duclos Disease (LDD) is a rare cerebellar lesion that has long been controversial as to whether the entity is a hamartoma, a malformation, or a neoplasm. Recent advances in metabolic imaging and molecular biology have unveiled biological features of LDD and a close relationship between LDD and Cowden disease. Adult onset LDD is now considered identical to Cowden disease in a US guideline. We present a case of LDD, in which high fluorodeoxy glucose (FDG) uptake was shown on PET/CT. We performed dual time point scans, in which a delayed scan exhibited more intense FDG uptake by the hamartomatous lesion than an early scan. We must remain aware of the possibility of LDD when intense accumulation is observed in a cerebellar lesion on FDG-PET/CT imaging.
Nakagawa
Toshio
T
Department of Radiology, Saiseikai Matsusaka General Hospital, Matsusaka, Japan.
Maeda
Masayuki
M
Kato
Mikiyoshi
M
Terada
Naohiro
N
Shimizu
Shigetoshi
S
Morooka
Yoshito
Y
Nakano
Hiroshi
H
Takeda
Kan
K
D000236:Adenoma / Q000150:complications; D000368:Aged; D002531:Cerebellum / Q000000981:diagnostic imaging* / Q000473:pathology; D019788:Fluorodeoxyglucose F18; D006223:Hamartoma Syndrome, Multiple / Q000150:complications / Q000000981:diagnostic imaging* / Q000473:pathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D049268:Positron-Emission Tomography; D019275:Radiopharmaceuticals; D013964:Thyroid Neoplasms / Q000150:complications; D014057:Tomography, X-Ray Computed
D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18