Measurement, interpretation, and implications of proteinuria and albuminuria.
Proteinuria is a common disorder in dogs and cats that can indicate the presence of chronic kidney disease (CKD) before the onset of azotemia or the presence of more severe CKD after the onset of azotemia. Although a direct pathogenetic link between glomerular disease, proteinuria, and progressive renal damage has not been established, attenuation of proteinuria has been associated with decreased renal functional decline in several studies. There is a need to continue to increase our understanding of the effects of proteinuria on the glomerulus, the tubule, and the interstitium in dogs and cats.
Grauer
Gregory F
GF
Department of Clinical Sciences, College of Veterinary Medicine, 111B Mosier Hall, Kansas State University, Manhattan, KS 66506, USA. ggrauer@vet.k-state.edu
D000419:Albuminuria / Q000175:diagnosis / Q000662:veterinary*; D000818:Animals; D002371:Cat Diseases / Q000175:diagnosis* / Q000652:urine; D002415:Cats; D003937:Diagnosis, Differential; D004283:Dog Diseases / Q000175:diagnosis* / Q000652:urine; D004285:Dogs; D007676:Kidney Failure, Chronic / Q000175:diagnosis / Q000652:urine / Q000662:veterinary; D011507:Proteinuria / Q000175:diagnosis / Q000662:veterinary*