[Electrophoretic behaviour of serum and liver proteins and of some isoenzymes in rats receiving a steatogenous, hyperlipidic, hypoprotein diet, with and without choline].
Albino rats were kept for long periods on a steatogenous, hypoproteic, hyperlipidic diets, either with or without choline. Serum protein and liver soluble protein and enzyme values showed changes that were only partly similar to those observed in human and experimental cirrhosis. The main features, in fact, were an absolute and percent decrease in albumins, an increase in serum alpha1-globulins and alpha proteins generally, and, more particularly, a constant fall in gamma-globulins and enzymes migrating to this site.
Notario
A
A
Istituto di Clinica Medica Generale e Terapia Medica dell'Università di Pavia.
Marcianò
S
S
Bobbio-Pallavicini
E
E
Bobbio-Pallavicini
F
F
Peona
C
C
D000361:Agammaglobulinemia / Q000209:etiology; D000821:Animal Feed / Q000032:analysis; D000818:Animals; D001219:Aspartate Aminotransferases / Q000032:analysis; D001797:Blood Protein Electrophoresis; D001798:Blood Proteins / Q000032:analysis*; D001835:Body Weight / Q000187:drug effects; D002794:Choline / Q000008:administration & dosage* / Q000627:therapeutic use; D002796:Choline Deficiency / Q000209:etiology / Q000378:metabolism*; D018753:Diet, Protein-Restricted / Q000009:adverse effects*; D004041:Dietary Fats / Q000008:administration & dosage / Q000633:toxicity*; D004588:Electrophoresis, Cellulose Acetate; D005260:Female; D034141:Hypoalbuminemia / Q000209:etiology; D007527:Isoenzymes / Q000032:analysis; D007770:L-Lactate Dehydrogenase / Q000032:analysis; D008099:Liver / Q000737:chemistry*; D008106:Liver Cirrhosis, Experimental / Q000209:etiology / Q000378:metabolism*; D008297:Male; D014176:Protein Biosynthesis; D011488:Protein Deficiency / Q000209:etiology / Q000378:metabolism*; D011506:Proteins / Q000032:analysis*; D051381:Rats; D017207:Rats, Sprague-Dawley; D014280:Triglycerides / Q000378:metabolism
D001798:Blood Proteins; D004041:Dietary Fats; D007527:Isoenzymes; D011506:Proteins; D014280:Triglycerides; D007770:L-Lactate Dehydrogenase; D001219:Aspartate Aminotransferases; D002794:Choline