[Occupational allergies to bromelain].
The protease bromelain originating from the pineapple fruit (Ananas comosus) finds frequent use in industry. Exposure to enzyme dusts has long been known to cause occupational allergies. The present paper reviews the results of the evaluation of literature data concerning occupational airway sensitization due to bromelain. Cases of specific airway sensitization caused by bromelain could be shown clearly by the presented studies. Since the symptoms, results of skin prick tests, detection of specific IgE antibodies and results of specific bronchoprovocation tests are consistent, an immunological mechanism can be assumed.
van Kampen
V
V
Berufsgenossenschaftliches Forschungsinstitut für Arbeitsmedizin. kampen@bgfa.de
Merget
R
R
Brüning
T
T
D000918:Antibody Specificity; D001963:Bromelains / Q000009:adverse effects* / Q000276:immunology*; D006801:Humans; D006967:Hypersensitivity / Q000175:diagnosis / Q000276:immunology*; D007074:Immunoglobulin G / Q000032:analysis; D009784:Occupational Diseases / Q000276:immunology*; D012882:Skin Tests
D007074:Immunoglobulin G; D001963:Bromelains