[Effect of Fructus Bruceae oil emulsion on cellular immune function and quality of life in patients with non-small cell lung cancer].
OBJECTIVE
To observe the effect of Fructus Bruceae oil emulsion (FBE) on cellular immune function (CIF) and quality of life (QOF) in patients with non-small cell lung cancer (NSCLC) after chemotherapy.


METHODS
One hundred and fifteen patients with mid-late stage NSCLC were randomly assigned to two groups, the 57 patients in the control group were only treated with chemotherapy of GP regimen, 58 in the treatment group with the chemotherapy of the same regimen and combined with FBE. The clinical efficacy was evaluated after two cycles of chemotherapy.


RESULTS
The effective rate was 51.8% and 47.4% in the treatment group and the control group respectively, the difference between them was insignificant (P > 0.05). CIF and QOF in the treatment group were better than those in the control group after chemotherapy respectively (P < 0.01), in the latter, CIF and QOF were desreased after chemotherapy (P < 0.05).


CONCLUSIONS
FBE combined with chemotherapy can improve the cellular immune function and quality of life in patients with mid-late stage NSCLC.
Tian
Hua-Qin
HQ
Department of Oncology, Foshan Hospital of Traditional Chinese Medicine, Guangdong. thq63@yahoo.com.cn
Yu
Shou-Yi
SY
Wang
Bin
B
D000328:Adult; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D032269:Brucea / Q000737:chemistry*; D002289:Carcinoma, Non-Small-Cell Lung / Q000188:drug therapy* / Q000276:immunology; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage; D004655:Emulsions; D005260:Female; D005638:Fruit / Q000737:chemistry; D006801:Humans; D007111:Immunity, Cellular / Q000187:drug effects; D008175:Lung Neoplasms / Q000188:drug therapy* / Q000276:immunology; D008297:Male; D008875:Middle Aged; D008517:Phytotherapy; D011788:Quality of Life; D016896:Treatment Outcome
D004365:Drugs, Chinese Herbal; D004655:Emulsions