title: Health-related quality of life among Canadians with migraine.
abstract: The objective was to determine the impact of migraine on health-related quality of life (HRQOL) among Canadians. Analysis was based on the public use microdata set of the Canadian Community Health Survey (CCHS), limited to those aged > or = 15 residing in Manitoba. HRQOL was measured using the SF-36 survey, which covers 8 health concepts. Multivariate linear regression was used to model each SF-36 scale against age, gender, education, income, migraine status and presence of mood or anxiety disorders. Of the 7236 CCHS respondents, 9.7% reported a diagnosis of migraine. Reported migraine predicted statistically significant (p<0.0001) lower HRQOL in all SF-36 domains with profound impairment of physical role, bodily pain and general health. Those reporting a mood disorder scored significantly lower in all domains with pronounced effects on emotional role, social functioning and general health. Reported anxiety disorder was associated with lower HRQOL in 6/8 domains. Canadians with migraine report significant impairment in HRQOL compared to the general population, independent of psychiatric morbidity.
authors.affiliation: IWK Health Centre, Department of Pediatrics, Division of Neurology, 5850 University Ave, Halifax, NS B3K 6R8, Canada. pbrna@hotmail.com
authors.forename: Paula
authors.initials: P
authors.lastname: Brna
authors.forename: Kevin
authors.initials: K
authors.lastname: Gordon
authors.forename: Joseph
authors.initials: J
authors.lastname: Dooley
mesh_terms: D000328:Adult; D002170:Canada / Q000453:epidemiology; D005260:Female; D006304:Health Status; D006306:Health Surveys; D006801:Humans; D008297:Male; D008875:Middle Aged; D008881:Migraine Disorders / Q000453:epidemiology* / Q000523:psychology*; D016017:Odds Ratio; D011788:Quality of Life; D012737:Sex Factors; D011795:Surveys and Questionnaires