title: Follicular lymphoma with extensive gastrointestinal tract involvement: follow-up by capsule endoscopy.
abstract: Follicular lymphoma with gastrointestinal tract involvement is rare. We describe the case of a young woman with follicular lymphoma with multiple nodular lesions involving segments of the proximal jejunum and terminal ileum. The presenting symptom was chronic diarrhea. The diagnosis was made by endoscopy with histologic examination of the mucosal lesions of the proximal and distal small intestine, immunohistochemical staining, and molecular analysis. The initial spread and pattern of the small bowel involvement, as well as treatment response, were evaluated by videocapsule endoscopy. The application of molecular analysis along with immunophenotypic evaluation has made it possible to precisely diagnose follicular lymphoma. In the present case, the use of capsule endoscopy improved the evaluation of the extent of small bowel involvement prior to and following treatment.
authors.affiliation: Department of Gastroenterology, Rabin Medical Center, Tel Aviv University, Beilinson Campus, Petah Tiqwa 49100, Israel.
authors.forename: Boris
authors.initials: B
authors.lastname: Sapoznikov
authors.forename: Sarah
authors.initials: S
authors.lastname: Morgenstern
authors.forename: Pia
authors.initials: P
authors.lastname: Raanani
authors.forename: Adina
authors.initials: A
authors.lastname: Aviram
authors.forename: Esther
authors.initials: E
authors.lastname: Rabizadeh
authors.forename: Miron
authors.initials: M
authors.lastname: Prokocimer
authors.forename: Yaron
authors.initials: Y
authors.lastname: Niv
mesh_terms: D000328:Adult; D001706:Biopsy; D053704:Capsule Endoscopy; D005260:Female; D006801:Humans; D007078:Ileal Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy; D007413:Intestinal Mucosa / Q000473:pathology; D007580:Jejunal Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy; D008224:Lymphoma, Follicular / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy