[A case of parathyroid hormone-related peptide producing gallbladder carcinoma presenting humoral hypercalcemia of malignancy].
Humoral hypercalcemia of malignancy (HHM) in neoplastic syndrome has been most commonly reported in squamous cell carcinoma. Gallbladder carcinoma with HHM is uncommon. In this report, we describe a male case of gallbladder carcinoma with marked hypercalcemia and a high level of serum parathyroid hormone-related peptide (PTHrP). An immunohistochemical examination using PTHrP was also positive.
Imoto
Yoshitaka
Y
Department of Digestive and Cardiovascular Medicine, University of Tokushima Graduate School.
Muguruma
Naoki
N
Kimura
Tetsuo
T
Kaji
Masako
M
Miyamoto
Hiroshi
H
Okamura
Seisuke
S
Ito
Susumu
S
Nakasono
Masahiko
M
Hirokawa
Mitsuyoshi
M
Sano
Toshiaki
T
D000230:Adenocarcinoma / Q000150:complications / Q000378:metabolism*; D005706:Gallbladder Neoplasms / Q000150:complications / Q000378:metabolism*; D006801:Humans; D006934:Hypercalcemia / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D044162:Parathyroid Hormone-Related Protein / Q000096:biosynthesis* / Q000097:blood
D044162:Parathyroid Hormone-Related Protein