title: Efficacy of aromatherapy (Lavandula angustifolia) as an intervention for agitated behaviours in Chinese older persons with dementia: a cross-over randomized trial.
abstract: BACKGROUND
  Agitated behaviours among persons with dementia are distressing to both patients and their caregivers. As pharmacological interventions may be limited by their potentially adverse effects, the use of complementary therapies for treatment of agitation has become more popular and aromatherapy is the fastest growing one.
  
  
  OBJECTIVE
  This study investigates the effectiveness of lavandula angustifolia (lavender) in treating agitated behaviours of demented people in Hong Kong.
  
  
  METHODS
  It was a cross-over randomized trial. Seventy Chinese older adults with dementia were recruited; half were randomly assigned to the active group (lavender inhalation) for three weeks and then switched to control group (sunflower inhalation) for another three weeks; the other half did the opposite. Clinical response was evaluated using the Chinese versions of Cohen-Mansfield Agitation Inventory (CCMAI) and Neuropsychiatric Inventory (CNPI).
  
  
  RESULTS
  The mean CCMAI total scores decreased from 24.68 to 17.77(t=10.79, df=69, p<0.001). The CNPI scores changed from 63.17 (SD=17.81) to 58.77 (SD=16.74) (t=14.59, df=69, p<0.001) after receiving Treatment A (Lavandula Angustifolia). There were no period and sequential effects noted.
  
  
  CONCLUSIONS
  In summary, lavender is effective as an adjunctive therapy in alleviating agitated behaviours in Chinese patients with dementia. In a patient population particularly vulnerable to side effects of psychotropic medications, aromatherapy using lavender may offer an alternative option.
authors.affiliation: Department of Occupational Therapy, Castle Peak Hospital, and Department of Psychiatry, Chinese University of Hong Kong, Hong Kong.
authors.forename: Pamela Wan-ki
authors.initials: PW
authors.lastname: Lin
authors.forename: Wai-chi
authors.initials: WC
authors.lastname: Chan
authors.forename: Bacon Fung-leung
authors.initials: BF
authors.lastname: Ng
authors.forename: Linda Chiu-wa
authors.initials: LC
authors.lastname: Lam
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000544:Alzheimer Disease / Q000208:ethnology / Q000523:psychology / Q000628:therapy*; D019341:Aromatherapy; D044466:Asian People / Q000523:psychology*; D000529:Complementary Therapies; D018592:Cross-Over Studies; D005260:Female; D006707:Homes for the Aged; D006723:Hong Kong; D006801:Humans; D027523:Lavandula; D008297:Male; D009735:Nursing Homes; D011595:Psychomotor Agitation / Q000208:ethnology / Q000523:psychology / Q000628:therapy*; D016896:Treatment Outcome