Modular synthesis of ChiraClick ligands: a library of P-chirogenic phosphines.
A library of novel and diverse P-chirogenic phosphine ligands containing a triazole moiety (ChiraClick ligands) were prepared in high yield in a modular fashion that allows for variation of both the phosphine and the triazole structure, as well as giving access to the two enantiomers of the ligand.
Dolhem
Franck
F
Organic Chemistry, Department of Chemical and Biological Engineering, Chalmers University of Technology, SE-41296 Göteborg, Sweden.
Johansson
Magnus J
MJ
Antonsson
Thomas
T
Kann
Nina
N
D020650:Combinatorial Chemistry Techniques / Q000379:methods*; D008024:Ligands; D015394:Molecular Structure; D010720:Phosphines / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism; D014230:Triazoles / Q000737:chemistry*
D008024:Ligands; D010720:Phosphines; D014230:Triazoles