title: [Patients' and physicians' perceptions on participation in a clinical trial: results on a survey in a French hospital].
abstract: OBJECTIVE
  We report the first survey on French physicians and patients participating to assess motivations prior enrolment and benefits and constraints perceived after participation.
  
  
  METHODS
  Twenty physicians were interviewed and 37 patients completed a questionnaire during clinical study participation.
  
  
  RESULTS
  If the main patient's motivation is altruistic, physician wish their own patient feel better. After participation, patient is satisfied with being part of a research effort and contributing to medical science. Effect of trial treatment on physical well-being seems less pronounced. Main constraint is the randomisation to placebo group. For physicians, the main benefit is getting research experience and training. Main constraints are logistical. Otherwise, perceptions on the same clinical trial depend on participant. In fact, physician usually overestimates constraints of clinical trial for patient.
  
  
  CONCLUSIONS
  The knowledge of patients and physicians perceptions of clinical trials and its taking into account should probably reduce difficulties in the recruitment in France.
authors.affiliation: Service Pharmaceutique, Hôpital de la Croix-Rousse, Lyon, France. agnes.henry@chu-lyon.fr
authors.forename: Agnès
authors.initials: A
authors.lastname: Henry
authors.forename: Stéphane
authors.initials: S
authors.lastname: Corvaisier
authors.forename: Sandrine
authors.initials: S
authors.lastname: Blanc
authors.forename: François
authors.initials: F
authors.lastname: Berthezene
authors.forename: Françoise
authors.initials: F
authors.lastname: Borson-Chazot
authors.forename: Emmanuel
authors.initials: E
authors.lastname: Broussolle
authors.forename: Philippe
authors.initials: P
authors.lastname: Ryvlin
authors.forename: Paul
authors.initials: P
authors.lastname: Touboul
mesh_terms: D000328:Adult; D000368:Aged; D001290:Attitude; D001291:Attitude of Health Personnel; D002986:Clinical Trials as Topic / Q000523:psychology*; D003625:Data Collection; D005260:Female; D005602:France; D006801:Humans; D008297:Male; D008875:Middle Aged; D010361:Patients; D010820:Physicians; D011795:Surveys and Questionnaires