[The influence of kanamycin, viomycin and ethambutol on the process of healing in experimental surgical wounds].
Experimentation of the action of kanamycin, viomycin and ethambutol in wound healing is reported. The planimetric measurement system of Carrel-Lecomte du Noüy was used to determine the development of the cicatrisation process. Prolongation of healing times in the 3rd and 4th periods is demonstrated and attributed to the general toxic action of these drugs, combined with direct toxic interference with epithelization and cicatrisation.
Emanuele
B
B
Ospedale San Luigi Gonzaga, Torino.
Andolfi
F
F
D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D004359:Drug Therapy, Combination; D004977:Ethambutol / Q000494:pharmacology*; D006168:Guinea Pigs; D007612:Kanamycin / Q000494:pharmacology*; D008432:Mathematical Computing; D023421:Models, Animal; D012038:Regeneration / Q000187:drug effects; D013530:Surgical Wound Infection / Q000188:drug therapy / Q000517:prevention & control*; D014756:Viomycin / Q000494:pharmacology*; D014945:Wound Healing / Q000187:drug effects*
D000900:Anti-Bacterial Agents; D007612:Kanamycin; D004977:Ethambutol; D014756:Viomycin