title: Viscoelasticity of isotropically cross-linked actin networks.
abstract: Despite their importance for the proper function of living cells, the physical properties of cross-linked actin networks remain poorly understood as the occurrence of heterogeneities hamper a quantitative physical description. The isotropic homogeneously cross-linked actin network presented here enables us to quantitatively relate the network response to a single filament model by determining the dominating length scale. The frequency dependence of the linear response and nonuniversal form of the nonlinear response reveal the importance of cross-linker unbinding events.
authors.affiliation: E22-Biophysics, Technische Universität München, James Franck Strasse, 85748 Garching, Germany.
authors.forename: R
authors.initials: R
authors.lastname: Tharmann
authors.forename: M M A E
authors.initials: MM
authors.lastname: Claessens
authors.forename: A R
authors.initials: AR
authors.lastname: Bausch
mesh_terms: D008841:Actin Cytoskeleton / Q000737:chemistry*; D000199:Actins / Q000737:chemistry*; D016880:Anisotropy; D003432:Cross-Linking Reagents / Q000737:chemistry; D004548:Elasticity; D008962:Models, Theoretical; D014783:Viscosity
chemical_list: D000199:Actins; D003432:Cross-Linking Reagents