title: Risk of contamination of nasal sprays in otolaryngologic practice.
abstract: BACKGROUND
  Reusable nasal-spray devices are frequently used in otolaryngologic examinations, and there is an increasing concern about the risk of cross-contamination from these devices. The aim of our study was to determine, by means of microbiologic analysis, the safety of a positive-displacement or pump-type atomizer after multiple uses.
  
  
  METHODS
  A reusable nasal spray bottle, pump, and tips were used in the nasal physical examination of 282 patients admitted to a tertiary otolaryngology clinic. The effectiveness of 2 different methods of prophylaxis against microbiologic contamination (the use of protective punched caps or rinsing the bottle tip with alcohol) was compared with that of a control procedure.
  
  
  RESULTS
  Although there was no statistically significant difference in positive culture rates among the types of nasal spray bottles tested, methicillin-resistant coagulase-negative staphylococci were isolated in 4 of 198 cultures.
  
  
  CONCLUSIONS
  Given these findings, we concluded that additional precautions (such as the use of an autoclave between sprays, disposable tips, or disposable devices) are warranted to avoid interpatient cross-contamination from a reusable nasal spray device.
authors.affiliation: Department of Otorhinolaryngology, Baskent University Faculty of Medicine, Ankara, Turkey. erdinca@baskent-ank.edu.tr
authors.forename: Erdinc
authors.initials: E
authors.lastname: Aydin
authors.forename: Evren
authors.initials: E
authors.lastname: Hizal
authors.forename: Babur
authors.initials: B
authors.lastname: Akkuzu
authors.forename: Ozlem
authors.initials: O
authors.lastname: Azap