title: [Successes and failures of ozena's medical treatment].
abstract: Ozena belongs to the primary atrophic rhinitis of unknow etiology. The incidence of this disease has markedly decrease in the last decades. We treated 4 patients with ozena between 2000-2005. The diagnosis was confirmed by physical and ENT examination, culture from the nose and CT scan of perinasal sinusis. Ciprofloxacin was aministrated orally in a dose 1,0-0,5 g daily to all patients. Also they were instructed how to clean the nose regularly with an isotonic saline solution and to moisteurse nosa by wotery spray. The treatment with ciprofloxacin was maintained for 4-6 weeks. In 3 causes the result was very good after 2-4 y observation. 1 patient, 16 y. old girl, didn't cooperate therapy propely - she stoped nasal rinsing after some improvement. The second course of treatment seems to get good result (3 months observation). Our and some other authors conclusion is: ciprofloxacin seems to be a promising drug for the treatment of ozena. For good results cleanising the nose regularly is importent as well as antibiotic.
authors.affiliation: Katedra i Klinika Otolaryngologii AM w Warszawie.
authors.forename: Irena
authors.initials: I
authors.lastname: Krzeska-Malinowska
authors.forename: Marta
authors.initials: M
authors.lastname: Held-Ziółkowska
authors.forename: G
authors.initials: G
authors.lastname: Januszek
mesh_terms: D000281:Administration, Intranasal; D000293:Adolescent; D000328:Adult; D000890:Anti-Infective Agents / Q000627:therapeutic use*; D002939:Ciprofloxacin / Q000627:therapeutic use*; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D008297:Male; D014663:Nasal Decongestants / Q000627:therapeutic use; D011044:Poland; D012189:Retrospective Studies; D012222:Rhinitis, Atrophic / Q000175:diagnosis / Q000188:drug therapy*; D016896:Treatment Outcome
chemical_list: D000890:Anti-Infective Agents; D014663:Nasal Decongestants; D002939:Ciprofloxacin