Sarcoidosis of the prostate.
A 55-year-old African-American man with clinical stage T1c prostate cancer underwent prostatectomy. Non-caseating, epithelioid granulomata adjacent to the anterior fibromuscular stroma were found incidentally. The granulomata included Langhans giant cells with rare conchoidal bodies. The distribution of the granulomata was not that of non-specific granulomatous prostatitis centred around ducts and glands. By immunohistochemistry, the epithelioid cells were positive for angiotensin-converting enzyme. The histological appearance suggested sarcoidosis, which was confirmed by the clinical history. Four years earlier, the patient had been treated for sarcoidosis.
Furusato
Bungo
B
Department of Genitourinary Pathology, Armed Forces Institute of Pathology, Washington, DC 20306-6000, USA.
Koff
Stacey
S
McLeod
David G
DG
Sesterhenn
Isabell A
IA
D000230:Adenocarcinoma / Q000150:complications; D006801:Humans; D033162:Incidental Findings; D008297:Male; D008875:Middle Aged; D011469:Prostatic Diseases / Q000150:complications / Q000473:pathology*; D011471:Prostatic Neoplasms / Q000150:complications; D012507:Sarcoidosis / Q000150:complications / Q000473:pathology*