title: Heart sensitivity to electrolyte composition of perfusion solution of rats after severe brain injury.
abstract: The in vitro model of isovolumic beating heart revealed enhanced sensitivity of the hearts from rats survived severe brain injury to concentration of Ca(2+), Na(+), and H(+) ions in the perfusion solution. Inhibition of myocardial contractile function after trauma was accompanied by destruction signs in cardiomyocyte sarcolemma and mitochondrial dysfunction.
authors.affiliation: Department of Pathophysiology with Clinical Pathophysiology Course, Omsk State Medical Academy. vvr@omsk-osma.ru
authors.forename: V V
authors.initials: VV
authors.lastname: Rusakov
authors.forename: V T
authors.initials: VT
authors.lastname: Dolgikh
mesh_terms: D000818:Animals; D001786:Blood Glucose; D001794:Blood Pressure / Q000187:drug effects*; D001930:Brain Injuries / Q000503:physiopathology*; D002118:Calcium / Q000494:pharmacology; D004573:Electrolytes / Q000494:pharmacology*; D006863:Hydrogen-Ion Concentration; D019344:Lactic Acid / Q000097:blood; D008297:Male; D009200:Myocardial Contraction / Q000187:drug effects* / Q000502:physiology; D010477:Perfusion; D051381:Rats; D017208:Rats, Wistar; D012964:Sodium / Q000494:pharmacology
chemical_list: D001786:Blood Glucose; D004573:Electrolytes; D019344:Lactic Acid; D012964:Sodium; D002118:Calcium