title: [Extraordinary manifestation of a gastric carcinoma by leptomeningeal carcinomatosis and spinal metastasis].
abstract: BACKGROUND
  Leptomeningeal carcinomatosis is a rare complication of solid tumors, e. g., breast, lung and gastrointestinal carcinomas. Clinical manifestations are variable with radicular pains with or without neurologic deficiencies as well as headache and hallucinations.
  
  
  METHODS
  The rare case of a 57-year-old patient with neurologic symptoms caused by a leptomeningeal carcinomatosis and a spinal metastasis of an asymptomatic signet-ring cell gastric carcinoma is reported. In spite of combined radiochemotherapy the patient died already 4 weeks after discharge from hospital due to an intracerebral hemorrhage.
  
  
  CONCLUSIONS
  Until today, prognosis of leptomeningeal carcinomatosis is poor with a median survival between 3-4 months independently of the primary tumor.
authors.affiliation: Klinik für Allgemeine Innere Medizin, Inselspital, Universitätsspital Bern, Bern, Schweiz.
authors.forename: Nicola
authors.initials: N
authors.lastname: Cresto
authors.forename: Alain
authors.initials: A
authors.lastname: Barth
authors.forename: Marlene
authors.initials: M
authors.lastname: Arnold
authors.forename: Rosemarie
authors.initials: R
authors.lastname: Weimann
authors.forename: Jürgen
authors.initials: J
authors.lastname: Gschossmann
authors.forename: Adrian F
authors.initials: AF
authors.lastname: Ochsenbein
authors.forename: Christos
authors.initials: C
authors.lastname: Kolotas
authors.forename: Hans-Jakob
authors.initials: HJ
authors.lastname: Peter
authors.forename: Uwe
authors.initials: U
authors.lastname: Schiemann
mesh_terms: D001706:Biopsy; D018279:Carcinoma, Signet Ring Cell / Q000175:diagnosis / Q000473:pathology / Q000556:secondary* / Q000628:therapy; D003937:Diagnosis, Differential; D018450:Disease Progression; D005773:Gastroscopy; D006801:Humans; D008159:Lumbar Vertebrae; D008207:Lymphatic Metastasis; D008279:Magnetic Resonance Imaging; D008297:Male; D008577:Meningeal Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000556:secondary* / Q000628:therapy; D008875:Middle Aged; D009367:Neoplasm Staging; D009460:Neurologic Examination; D011128:Polyradiculopathy / Q000175:diagnosis / Q000209:etiology; D012447:Sacrum; D013120:Spinal Cord Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000556:secondary* / Q000628:therapy; D013270:Stomach / Q000473:pathology; D013274:Stomach Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy