title: Effect of computer-aided detection as a second reader in multidetector-row CT colonography.
abstract: Our purpose was to assess the effect of computer-aided detection (CAD) on lesion detection as a second reader in computed tomographic colonography, and to compare the influence of CAD on the performance of readers with different levels of expertise. Fifty-two CT colonography patient data-sets (37 patients: 55 endoscopically confirmed polyps > or =0.5 cm, seven cancers; 15 patients: no abnormalities) were retrospectively reviewed by four radiologists (two expert, two nonexpert). After primary data evaluation, a second reading augmented with findings of CAD (polyp-enhanced view, Siemens) was performed. Sensitivities and reading time were calculated for each reader without CAD and supported by CAD findings. The sensitivity of expert readers was 91% each, and of nonexpert readers, 76% and 75%, respectively, for polyp detection. CAD increased the sensitivity of expert readers to 96% (P = 0.25) and 93% (P = 1), and that of nonexpert readers to 91% (P = 0.008) and 95% (P = 0.001), respectively. All four readers diagnosed 100% of cancers, but CAD alone only 43%. CAD increased reading time by 2.1 min (mean). CAD as a second reader significantly improves sensitivity for polyp detection in a high disease prevalence population for nonexpert readers. CAD causes a modest increase in reading time. CAD is of limited value in the detection of cancer.
authors.affiliation: Department of Radiology, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria. thomas.mang@meduniwien.ac.at
authors.forename: Thomas
authors.initials: T
authors.lastname: Mang
authors.forename: Philipp
authors.initials: P
authors.lastname: Peloschek
authors.forename: Christina
authors.initials: C
authors.lastname: Plank
authors.forename: Andrea
authors.initials: A
authors.lastname: Maier
authors.forename: Anno
authors.initials: A
authors.lastname: Graser
authors.forename: Michael
authors.initials: M
authors.lastname: Weber
authors.forename: Christian
authors.initials: C
authors.lastname: Herold
authors.forename: Luca
authors.initials: L
authors.lastname: Bogoni
authors.forename: Wolfgang
authors.initials: W
authors.lastname: Schima
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003110:Colonic Neoplasms / Q000000981:diagnostic imaging*; D003111:Colonic Polyps / Q000000981:diagnostic imaging*; D023881:Colonography, Computed Tomographic; D003936:Diagnosis, Computer-Assisted; D005260:Female; D006801:Humans; D021621:Imaging, Three-Dimensional; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012680:Sensitivity and Specificity