title: The current role of imaging for prostate brachytherapy.
abstract: Prostate brachytherapy is a radiotherapy technique for early stage prostate cancer that uses imaging guidance to place radioactive sources directly into the prostate gland. Transrectal ultrasound is used to facilitate a template-guided transperineal approach to the prostate and permits a highly conformal method of prostate radiotherapy with doses far higher than can be achieved with other radiation techniques. Maturing data has validated this technique as an acceptable treatment option with favourable and durable biochemical outcomes. The radiologist has a major role to play in the process: patient selection, guiding source delivery and follow-up after treatment all require close collaboration with colleagues in Radiation Oncology and Medical Physics. This review emphasises the specific contribution of imaging in the context of currently reported outcomes data.
authors.affiliation: Radiology Department, Cookridge Hospital, Leeds, LS16 6QB, UK. brendan.carey@leedsth.nhs.uk
authors.forename: Brendan
authors.initials: B
authors.lastname: Carey
authors.forename: Sarah
authors.initials: S
authors.lastname: Swift
mesh_terms: D000230:Adenocarcinoma / Q000000981:diagnostic imaging / Q000532:radiotherapy*; D014408:Biomarkers, Tumor / Q000097:blood; D001918:Brachytherapy / Q000009:adverse effects; D004343:Drug Implants; D005471:Fluoroscopy; D005500:Follow-Up Studies; D005544:Forecasting; D006801:Humans; D007457:Iodine Radioisotopes / Q000008:administration & dosage / Q000627:therapeutic use; D008279:Magnetic Resonance Imaging; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D009364:Neoplasm Recurrence, Local / Q000000981:diagnostic imaging; D009929:Organ Size; D010165:Palladium / Q000008:administration & dosage / Q000627:therapeutic use; D017430:Prostate-Specific Antigen / Q000097:blood; D011471:Prostatic Neoplasms / Q000097:blood / Q000000981:diagnostic imaging / Q000532:radiotherapy*; D011832:Radiation Injuries / Q000209:etiology; D011868:Radioisotopes / Q000008:administration & dosage / Q000627:therapeutic use; D015642:Radiology, Interventional; D019275:Radiopharmaceuticals / Q000008:administration & dosage / Q000627:therapeutic use; D011879:Radiotherapy Dosage; D047368:Tumor Burden; D014463:Ultrasonography; D036761:Ultrasound, High-Intensity Focused, Transrectal; D014555:Urination Disorders / Q000209:etiology
chemical_list: D014408:Biomarkers, Tumor; D004343:Drug Implants; D007457:Iodine Radioisotopes; D011868:Radioisotopes; D019275:Radiopharmaceuticals; D010165:Palladium; D017430:Prostate-Specific Antigen