Individual differences in cortisol levels and performance on a test of executive function in men and women.
Despite evidence for a high concentration of corticosteroid receptors in prefrontal cortex, little research has examined the relationship between cortisol and prefrontal cortical function other than working memory. We investigated the association between salivary cortisol levels and performance on the Wisconsin Card Sorting Test (WCST) of executive function and on a test of mental rotation (to test specificity of the relationship between cortisol and cognitive performance) in men and women (n=116, ages 17-22). Higher cortisol levels at the beginning of the test session were associated with more errors in women on the WCST and fewer errors in men. However, men's cortisol levels were lower than women's at this point in time. Cortisol levels were not associated with mental rotation scores. Our results suggest that individual differences in cortisol levels among participants upon arrival to a test situation influence performance on a task involving the prefrontal cortex.
McCormick
C M
CM
Neuroscience Program, Bates College, Lewiston, ME 04240, USA. cmccormi@brocku.ca
Lewis
E
E
Somley
B
B
Kahan
T A
TA
D000293:Adolescent; D000328:Adult; D005260:Female; D006801:Humans; D006854:Hydrocortisone / Q000097:blood / Q000378:metabolism*; D007092:Imagination / Q000502:physiology; D007206:Individuality; D008297:Male; D009483:Neuropsychological Tests; D017397:Prefrontal Cortex / Q000502:physiology; D011597:Psychomotor Performance / Q000502:physiology*; D012463:Saliva / Q000378:metabolism; D012727:Sex Characteristics; D013028:Space Perception / Q000502:physiology
D006854:Hydrocortisone