title: [Analysis of disturbances of oesophageal phase of swallowing in patients with amyotrophic lateral sclerosis (ALS)].
abstract: BACKGROUND
  The occurrence of the disturbances of oropharyngeal phases of swallowing in Amyotrophic Lateral Sclerosis (ALS) patients has been well documented.
  
  
  OBJECTIVE
  Assessment of the oesophageal manometry for detection of the oesophageal phase of swallowing in ALS patients.
  
  
  METHODS
  The study was carried out in 12 dysphagic ALS patients and 10 sex- and age- matched healthy volunteers.
  
  
  RESULTS
  The mean upper oesophageal contractile: amplitude, duration and velocity during the wet and dry swallows in ALS individuals were statistically differ as compared to control subjects. The abnormalities of vocal folds function was also found in the fiberoscopy examination of larynx in all ALS patients.
  
  
  CONCLUSIONS
  This study reveal the occurrence of disturbances of the oesophageal phase of swallowing in ALS patients with dysphagia.
authors.affiliation: Katedra i Klinika Otolaryngologii, Uniwersytet Jagielloński, Collegium Medicum Kraków. jtomik@poczta.fm
authors.forename: Jerzy
authors.initials: J
authors.lastname: Tomik
authors.forename: Barbara
authors.initials: B
authors.lastname: Tomik
authors.forename: Krzysztof
authors.initials: K
authors.lastname: Lorens
authors.forename: Maciej
authors.initials: M
authors.lastname: Wiatr
authors.forename: Jacek
authors.initials: J
authors.lastname: Składzień
mesh_terms: D000690:Amyotrophic Lateral Sclerosis / Q000150:complications* / Q000503:physiopathology*; D003679:Deglutition / Q000502:physiology; D003680:Deglutition Disorders / Q000209:etiology* / Q000503:physiopathology*; D004947:Esophagus / Q000502:physiology / Q000503:physiopathology; D005260:Female; D006801:Humans; D008297:Male; D008365:Manometry; D008875:Middle Aged; D010528:Peristalsis; D010609:Pharyngeal Muscles / Q000502:physiology / Q000503:physiopathology; D012016:Reference Values; D012720:Severity of Illness Index