[The use of P300 event-related potentials in the evaluation of the effectiveness of therapy of episodic exertional headaches].
Fifteen healthy individuals and 17 patients with episodic exertional headaches were examined before and after treatment with citalopram using P300 event-related potentials. Unlike healthy controls, patients with headaches before treatment displayed an increase in P300 amplitude and the loss of its habituation, which correlated with a decrease in cognitive functions. The treatment lowered the degree of pain and vegetative syndromes, normalized P300 parameters, and improved cognitive functions. The use of P300 method may be an additional criterion of the effectiveness of therapy in patients with exertional headaches.
Gordeev
S A
SA
Riabokon'
I V
IV
Tabeeva
G R
GR
Filatova
E G
EG
Posokhov
S I
SI
Golubev
V L
VL
Veĭn
A M
AM
D000161:Acoustic Stimulation; D000328:Adult; D015283:Citalopram / Q000627:therapeutic use*; D005072:Evoked Potentials, Auditory / Q000187:drug effects / Q000502:physiology*; D005260:Female; D005500:Follow-Up Studies; D051270:Headache Disorders, Primary / Q000188:drug therapy / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D017367:Selective Serotonin Reuptake Inhibitors / Q000627:therapeutic use*; D016896:Treatment Outcome
D015283:Citalopram; D017367:Selective Serotonin Reuptake Inhibitors