[Glucocorticoid induced osteoporosis].
Secondary osteoporosis is caused by various non-physiological factors. It affects 5% of all patients with osteoporosis and accounts for 20% of all osteoporotic fractures. Glucocorticoid induced osteoporosis is the most common form of secondary osteoporosis, whereas an endogenous Cushing syndrome rarely results in decreased bone mineral density. In addition, chronic inflammatory diseases which require a glucocorticoid therapy also need to be considered in the context of osteoporosis. This article presents the current data on glucocorticoid induced osteoporosis and an update of the proposed DVO (Dachverbandes Osteologie, umbrella organization of German scientific osteology-related societies) guidelines 2006.
Lange
U
U
Abt. Rheumatologie, Klinische Immunologie, Physikalische Medizin und Osteologie, Kerckhoff-Klinik, Benekestrasse 2-8, 61231 Bad Nauheim. U.Lange@kerckhoff-klinik.de
Müller-Ladner
U
U
D000893:Anti-Inflammatory Agents / Q000009:adverse effects*; D005938:Glucocorticoids / Q000009:adverse effects*; D006801:Humans; D010024:Osteoporosis / Q000139:chemically induced* / Q000517:prevention & control*; D017410:Practice Guidelines as Topic; D010818:Practice Patterns, Physicians' / Q000639:trends*
D000893:Anti-Inflammatory Agents; D005938:Glucocorticoids