title: Platelet-leukocyte interactions in inflammation and atherothrombosis.
abstract: Inflammatory processes at the vascular wall result in the development of atherosclerosis. Platelet interactions with leukocytes may play a key role in the initiation of inflammation. They trigger autocrine and paracrine activation processes, leading to leukocyte recruitment (in)to the vascular wall. This article highlights the molecular basis and the inflammatory pathways initiated by platelet-leukocyte interactions.
authors.affiliation: Medizinische Klinik III, Eberhard Karls Universität Tübingen, Tübingen, Germany. andreas.may@med.uni-tuebingen.de
authors.forename: Andreas E
authors.initials: AE
authors.lastname: May
authors.forename: Harald
authors.initials: H
authors.lastname: Langer
authors.forename: Peter
authors.initials: P
authors.lastname: Seizer
authors.forename: Boris
authors.initials: B
authors.lastname: Bigalke
authors.forename: Stephan
authors.initials: S
authors.lastname: Lindemann
authors.forename: Meinrad
authors.initials: M
authors.lastname: Gawaz
mesh_terms: D001157:Arterial Occlusive Diseases / Q000209:etiology; D001792:Blood Platelets / Q000473:pathology / Q000502:physiology; D002450:Cell Communication / Q000502:physiology*; D002634:Chemotaxis, Leukocyte; D004730:Endothelium, Vascular / Q000473:pathology; D006801:Humans; D007249:Inflammation / Q000209:etiology*; D007962:Leukocytes / Q000473:pathology / Q000502:physiology; D013927:Thrombosis / Q000209:etiology*