title: [Cure effects of Jiangu Fufang on osteoporotic model induced by ovariectomy].
abstract: OBJECTIVE
  To explore the cure effects of Jiangu Fufang on osteoporotic model induced by ovariectomy.
  
  
  METHODS
  Rats were ovariectomized and administered drugs for 3 monthes. Bone mineral density and biomechanics properties, histomorphometric analysis and biochemical index such as calcium, phosphorus, alkaline phosphatase were detected.
  
  
  RESULTS
  Jiangu Fufang could significantly increase bone density and biomechanics properties. The level of calcium, phosphorus and alkaline phosphatase were restored by Jiangu Fufang. Jiangu Fufang could significantly increase area of bone trabecula, thickness of cortical bone and bone trabecula.
  
  
  CONCLUSIONS
  Jiangu Fufang could cure osteoporosis through increasing bone mineral density, improving bone biomechanics properties, and effecting bone metabolism.
authors.affiliation: The General Hospital, the Air Force of the Chinese People's Liberation Army, Beijing 100036, China.
authors.forename: Ying-Xian
authors.initials: YX
authors.lastname: Deng
authors.forename: Zeng-Chun
authors.initials: ZC
authors.lastname: Ma
authors.forename: Hong-Ling
authors.initials: HL
authors.lastname: Tan
authors.forename: Cheng-Rong
authors.initials: CR
authors.lastname: Xiao
authors.forename: Yu-Guang
authors.initials: YG
authors.lastname: Wang
authors.forename: Yue
authors.initials: Y
authors.lastname: Gao
mesh_terms: D000469:Alkaline Phosphatase / Q000097:blood; D000818:Animals; D001696:Biomechanical Phenomena; D015519:Bone Density / Q000187:drug effects*; D002118:Calcium / Q000097:blood; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification / Q000494:pharmacology* / Q000627:therapeutic use; D005260:Female; D005269:Femur / Q000503:physiopathology; D008159:Lumbar Vertebrae / Q000187:drug effects / Q000473:pathology / Q000503:physiopathology; D010024:Osteoporosis / Q000097:blood / Q000188:drug therapy* / Q000503:physiopathology; D010052:Ovariectomy; D010758:Phosphorus / Q000097:blood; D008517:Phytotherapy; D010946:Plants, Medicinal / Q000737:chemistry*; D011897:Random Allocation; D051381:Rats; D017207:Rats, Sprague-Dawley
chemical_list: D004338:Drug Combinations; D004365:Drugs, Chinese Herbal; C528308:jiangu fufang; D010758:Phosphorus; D000469:Alkaline Phosphatase; D002118:Calcium