A case of anaphylactic reaction to praziquantel treatment.
A 35-year-old Chinese man was administered praziquantel for clonorchiasis, and 30 minutes later he experienced a sudden onset of itching urticaria over his entire body with dyspnea, palpitation, and dizziness. The patient had no recent medication history except for the praziquantel. He was diagnosed as having an anaphylactic reaction with skin eruptions induced by praziquantel. His symptoms subsided after a stomach wash and the administration of anti-anaphylactic medication in emergency department of a regional hospital in the People's Republic of China. The immediate type of hypersensitive reaction to praziquantel is plausible, and this reaction should be considered for praziquantel therapy.
Shen
Chenghua
C
Department of Parasitology and Tropical Medicine, Seoul National University College of Medicine, Republic of Korea, and Department of Internal Medicine, Heilongjiang Provincial Zhaoyuan People's Hospital, Zhaoyuan, People's Republic of China.
Choi
Min-Ho
MH
Bae
Young Mee
YM
Yu
Gui
G
Wang
Shuhua
S
Hong
Sung-Tae
ST
D000328:Adult; D000707:Anaphylaxis / Q000139:chemically induced*; D000871:Anthelmintics / Q000009:adverse effects*; D003003:Clonorchiasis / Q000188:drug therapy; D003875:Drug Eruptions / Q000209:etiology*; D006801:Humans; D008297:Male; D011223:Praziquantel / Q000009:adverse effects*
D000871:Anthelmintics; D011223:Praziquantel