title: Leukocytospermia: relationship to sperm deoxyribonucleic acid integrity in patients evaluated for male factor infertility.
abstract: The purpose of our study was to analyze the relationship of leukocytospermia to sperm DNA damage as assessed by the DNA integrity assay. Results indicate that leukocytospermia has a significant negative effect on the standard semen parameters of concentration, motility, and morphology but at most a very weak effect on DNA integrity as measured by the DNA fragmentation assay.
authors.affiliation: Andrology Laboratory, Department of Pathology and Laboratory Medicine, Mount Sinai Hospital, Toronto, Ontario, Canada.
authors.forename: Sergey I
authors.initials: SI
authors.lastname: Moskovtsev
authors.forename: Jennifer
authors.initials: J
authors.lastname: Willis
authors.forename: John
authors.initials: J
authors.lastname: White
authors.forename: J Brendan M
authors.initials: JB
authors.lastname: Mullen
mesh_terms: D000328:Adult; D004247:DNA / Q000235:genetics*; D006801:Humans; D007248:Infertility, Male / Q000235:genetics* / Q000473:pathology / Q000503:physiopathology; D007958:Leukocyte Count; D007962:Leukocytes / Q000473:pathology*; D008297:Male; D013094:Spermatozoa / Q000473:pathology / Q000502:physiology*
chemical_list: D004247:DNA