title: Preliminary feasibility and efficacy of a brief motivational intervention with psychophysiological feedback for cocaine abuse.
abstract: Motivational interviewing (MI) with personalized feedback, particularly related to biological markers of risk or harm, has been found effective for alcohol use disorders, but has not been fully investigated in cocaine use disorders. A randomized, controlled pilot study evaluating the feasibility and preliminary efficacy of a brief MI intervention using EEG/ERP graphical feedback for cocaine abusers was conducted. Treatment-seeking cocaine abusers (N = 31) were randomly assigned to a two-session MI intervention or a minimal control condition. All participants received EEG assessments at intake and post-treatment. Results indicated that the MI intervention was feasible and the subjective impact of the EEG feedback was positive. Significant group differences in percentage of cocaine positive urine screens across the study were found, favoring the MI group; 84.9% for the control group and 62.6% in the MI group, p < .05. Further research must determine the specific conditions under which MI is most appropriate and efficacious.
authors.affiliation: Department of Family & Community Medicine, Houston, TX 77030, USA. Angela.L.Stotts@uth.tmc.edu
authors.forename: Angela L
authors.initials: AL
authors.lastname: Stotts
authors.forename: Geoffrey F
authors.initials: GF
authors.lastname: Potts
authors.forename: Gina
authors.initials: G
authors.lastname: Ingersoll
authors.forename: Mary Reeni
authors.initials: MR
authors.lastname: George
authors.forename: Laura E
authors.initials: LE
authors.lastname: Martin
mesh_terms: D000328:Adult; D001288:Attention / Q000187:drug effects / Q000502:physiology; D001931:Brain Mapping; D002540:Cerebral Cortex / Q000187:drug effects / Q000503:physiopathology; D003042:Cocaine / Q000633:toxicity*; D019970:Cocaine-Related Disorders / Q000503:physiopathology / Q000523:psychology / Q000534:rehabilitation*; D004569:Electroencephalography / Q000187:drug effects*; D018913:Event-Related Potentials, P300 / Q000187:drug effects; D005240:Feasibility Studies; D030141:Feedback, Psychological; D006801:Humans; D008297:Male; D008875:Middle Aged; D009042:Motivation; D010364:Pattern Recognition, Visual / Q000187:drug effects / Q000502:physiology; D010897:Pitch Discrimination / Q000187:drug effects / Q000502:physiology; D011614:Psychotherapy, Brief; D016896:Treatment Outcome
chemical_list: D003042:Cocaine