[Ultrastructure of endocrine cells in the dog pancreas].
Electron microscopy was used to study the cellular composition of dog pancreatic islets. Four types of endocrine cells were detected: A, B, D and PP. B cells were the predominant population within the islets. Differences in cellular organization of A and B cells were shown to be caused by the phases of the process of hormone synthesis. Insulin-containing secretory granules in B cells had a crystalloid structure, similar to that in B granules of insulin-containing cells in human pancreatic islets. In the exocrine portion of the pancreas, acino-insular cells were detected that simultaneously contained B granules and zymogen granules in their cytoplasm. It is suggested, that their presence is indicative of one of possible directions of pancreatic islet regeneration.
Puzyrev
A A
AA
Ivanova
V F
VF
Kostiukevich
S V
SV
D000818:Animals; D004285:Dogs; D007515:Islets of Langerhans / Q000166:cytology / Q000648:ultrastructure*