title: Mesoporous silicon: a platform for the delivery of therapeutics.
abstract: Nanostructuring materials can radically change their properties. Two interesting examples highlighted here are nanoscale porosity inducing biodegradability, and nanoscale confinement affecting the physical form of an entrapped drug. Mesoporous silicon is under increasing study for drug-delivery applications, and is the topic of this review. The authors focus on those properties of most relevance to this application, as well as those recent studies published on small molecule and peptide/protein delivery.
authors.affiliation: University of South Australia, Ian Wark Research Institute, Australia.
authors.forename: Clive A
authors.initials: CA
authors.lastname: Prestidge
authors.forename: Timothy J
authors.initials: TJ
authors.lastname: Barnes
authors.forename: Chi-Hian
authors.initials: CH
authors.lastname: Lau
authors.forename: Christian
authors.initials: C
authors.lastname: Barnett
authors.forename: Armando
authors.initials: A
authors.lastname: Loni
authors.forename: Leigh
authors.initials: L
authors.lastname: Canham
mesh_terms: D002626:Chemistry, Pharmaceutical; D004339:Drug Compounding / Q000379:methods; D016503:Drug Delivery Systems / Q000379:methods*; D008422:Materials Testing; D049329:Nanostructures / Q000737:chemistry*; D036103:Nanotechnology / Q000379:methods*; D010455:Peptides; D004364:Pharmaceutical Preparations / Q000737:chemistry*; D016062:Porosity; D011506:Proteins; D012666:Semiconductors; D012825:Silicon / Q000737:chemistry*
chemical_list: D010455:Peptides; D004364:Pharmaceutical Preparations; D011506:Proteins; D012825:Silicon