Effect of peracetylation on the conformation of gamma-cyclodextrin.
The well-known, fourfold symmetry of the gamma-CD molecule in its solid inclusion complexes is lost on peracetylation, which yields a highly distorted host molecule in which self-inclusion of acetyl residues divides the macrocyclic cavity into two distinct sub-cavities that accommodate solvent molecules.
Caira
Mino R
MR
Department of Chemistry, University of Cape Town, Rondebosch, 7701, South Africa. Mino.Caira@uct.ac.za
Bettinetti
Giampiero
G
Sorrenti
Milena
M
Catenacci
Laura
L
Cruickshank
Dyanne
D
Davies
Kate
K
D000107:Acetylation; D002240:Carbohydrate Sequence; D008968:Molecular Conformation; D008969:Molecular Sequence Data; D014961:X-Ray Diffraction; D047408:gamma-Cyclodextrins / Q000737:chemistry*
D047408:gamma-Cyclodextrins; C023792:gamma-cyclodextrin