The relationship between cognitive dysfunction and stress sensitivity in schizophrenia: a replication study.
The aim of the current study was to replicate the finding that cognitive impairments are not or inversely associated with sensitivity to stress in a sample of 25 patients diagnosed with psychotic disorder. The results indicated that impairments in performance on the Trailmaking Test and the Stroop Color Word Test were inversely associated with sensitivity to stress in daily life, whereas impairment in a subtest of the Behavioral Assessment of Dysexecutive Syndrome (BADS) was not associated with stress-sensitivity. The data thus show that in some instances cognitive functioning is not, and in other instances is inversely associated with momentary sensitivity to stress. Cognitive impairment and affective reactivity thus appear to be independent or mutually exclusive mechanisms in psychosis, suggesting competing causal pathways.
Morrens
Manuel
M
Collaborative Antwerp Psychiatric Research Institute, Campus Drie Eiken, Antwerp, Belgium.
Krabbendam
Lydia
L
Bak
Maarten
M
Delespaul
Phillippe
P
Mengelers
Ron
R
Sabbe
Bernard
B
Hulstijn
Wouter
W
van Os
Jim
J
Myin-Germeys
Inez
I
D000328:Adult; D010054:Brief Psychiatric Rating Scale; D003072:Cognition Disorders / Q000175:diagnosis / Q000453:epidemiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D015995:Prevalence; D015203:Reproducibility of Results; D012559:Schizophrenia / Q000175:diagnosis / Q000453:epidemiology*; D012680:Sensitivity and Specificity; D013315:Stress, Psychological / Q000175:diagnosis* / Q000453:epidemiology* / Q000523:psychology