title: Ruthenium-catalyzed ring-closing metathesis to form tetrasubstituted olefins.
abstract: [structure: see text]. Increased efficiency for ring-closing metathesis to form tetrasubstituted olefins using N-heterocyclic carbene ligated ruthenium catalysts was achieved by reducing the size of the substituents at the ortho positions of the N-bound aryl rings.
authors.affiliation: The Arnold and Mabel Beckman Laboratories of Chemical Synthesis, Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA 91125, USA.
authors.forename: Jacob M
authors.initials: JM
authors.lastname: Berlin
authors.forename: Katie
authors.initials: K
authors.lastname: Campbell
authors.forename: Tobias
authors.initials: T
authors.lastname: Ritter
authors.forename: Timothy W
authors.initials: TW
authors.lastname: Funk
authors.forename: Anatoly
authors.initials: A
authors.lastname: Chlenov
authors.forename: Robert H
authors.initials: RH
authors.lastname: Grubbs