New challenges for the diagnosis of feline immunodeficiency virus infection.
Vaccination of cats against feline immunodeficiency virus (FIV) with a whole-virus vaccine results in rapid and persistent production of antibodies that are indistinguishable from those used for diagnosis of FIV infection. There are no diagnostic tests available for veterinary practitioners at the present time to resolve the diagnostic dilemma posed by use of whole-virus vaccines for protection of cats against FIV. There is a great need for development of commercially available rapid diagnostic tests that conform to differentiation of infected from vaccinated animals standards.
Crawford
P Cynda
PC
Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, 2015 SW 16th Avenue, Gainesville, FL 32610, USA. crawfordc@mail.vetmed.ufl.edu
Levy
Julie K
JK
D000818:Animals; D000914:Antibodies, Viral / Q000096:biosynthesis; D002415:Cats; D003937:Diagnosis, Differential; D016181:Feline Acquired Immunodeficiency Syndrome / Q000175:diagnosis*; D016089:Immunodeficiency Virus, Feline / Q000276:immunology* / Q000302:isolation & purification; D012680:Sensitivity and Specificity; D014765:Viral Vaccines / Q000276:immunology*
D000914:Antibodies, Viral; D014765:Viral Vaccines