title: The active platelet: translation and protein synthesis in an anucleate cell.
abstract: Platelets are the major cellular component of the hemostatic system that controls vessel and wound repair. However, platelets also have a variety of additional functions in inflammatory responses and host defense. The function and structure of the platelet was assumed to be very simple for a long period of time. With more modern tools of investigation such as cDNA arrays and proteomics, we have discovered a cell that is becoming a more sophisticated libero that functions in the classic mechanisms of white blood cells--inflammation and immunity.
authors.affiliation: Medizinische Klinik III, Eberhard Karls-Universität Tübingen, Tübingen, Germany. stephan.lindemann@med.uni-tuebingen.de
authors.forename: Stephan
authors.initials: S
authors.lastname: Lindemann
authors.forename: Meinrad
authors.initials: M
authors.lastname: Gawaz
mesh_terms: D000818:Animals; D001792:Blood Platelets / Q000276:immunology / Q000378:metabolism* / Q000502:physiology; D006801:Humans; D015539:Platelet Activation; D014176:Protein Biosynthesis; D040901:Proteomics