title: Natural history of the canine vein pouch aneurysm model.
abstract: OBJECTIVE
  The canine vein pouch aneurysm model is widely used for testing and development of devices directed at the endovascular treatment of aneurysms. Our purpose was to determine the incidence of spontaneous thrombosis and rupture of these aneurysms.
  
  
  METHODS
  A retrospective review of laboratory records of canine vein pouch aneurysms made during a 6-year period was performed. The aneurysm and parent artery dimensions as well as incidences of spontaneous thrombosis and rupture were noted.
  
  
  RESULTS
  During the interval studied, 326 vein patch aneurysms were made in 310 canines. Of these, 102 were sidewall (lateral) and 224 were bifurcation aneurysms. Spontaneous occlusion occurred in 9 of the sidewall aneurysms and in only 1 of the bifurcation aneurysms. None of the aneurysms ruptured.
  
  
  CONCLUSIONS
  Spontaneous occlusion of the sidewall canine vein patch aneurysm occurred less than 10% of the time; in the bifurcation aneurysms, it almost never occurred. These characteristics enhance the value of this model for use in testing of devices intended for the endovascular treatment of aneurysms.
authors.affiliation: Departments of Radiology, University of Wisconsin Hospital and Clinics, Madison, WI 53792, USA. as.turk@hosp.wisc.edu
authors.forename: A S
authors.initials: AS
authors.lastname: Turk
authors.forename: B
authors.initials: B
authors.lastname: Aagaard-Kienitz
authors.forename: D
authors.initials: D
authors.lastname: Niemann
authors.forename: D
authors.initials: D
authors.lastname: Consigny
authors.forename: A
authors.initials: A
authors.lastname: Rappe
authors.forename: J
authors.initials: J
authors.lastname: Grinde
authors.forename: C M
authors.initials: CM
authors.lastname: Strother
mesh_terms: D000783:Aneurysm / Q000000981:diagnostic imaging / Q000453:epidemiology* / Q000628:therapy*; D017542:Aneurysm, Ruptured / Q000453:epidemiology; D015901:Angiography, Digital Subtraction; D000818:Animals; D004195:Disease Models, Animal; D004285:Dogs; D004621:Embolization, Therapeutic; D015994:Incidence; D013927:Thrombosis / Q000453:epidemiology; D014680:Veins