Proactive interference in a semantic short-term memory deficit: role of semantic and phonological relatedness.
Previous research has indicated that patients with semantic short-term memory (STM) deficits demonstrate unusual intrusions of previously presented material during serial recall tasks (Martin and Lesch, 1996). These intrusions suggest excessive proactive interference (PI) from previous lists. Here, we explore one such patient's susceptibility to PI. Experiment 1 demonstrated patient M.L.'s extreme susceptibility to PI using a probe recognition task that manipulates the recency of negative probes (the recent negatives task). When stimuli consisted of letters, M.L. showed greatly exaggerated effects of PI, well outside of the range of healthy control participants. Experiment 2 used a variation of the recent negatives task to examine the relative contribution of semantic and phonological relatedness in PI. This task manipulated semantic and phonological relatedness of probes and recently presented list items. Relative to healthy control participants, patient M.L. showed exaggerated interference effects for both phonological and semantically related probes, both for probes related to the current list and for probes related to the previous list. These data have important implications for theories of semantic STM deficits. Specifically, these data suggest that it is not the rapid decay of semantic representations that is responsible for difficulties in short-term recall, but rather the abnormal persistence of previously presented material. We propose that this susceptibility to PI is the result of a deficit in control processes acting on STM.
Hamilton
A Cris
AC
Psychology Department, Rice University, Houston, TX 77251, USA.
Martin
Randi C
RC
D001184:Articulation Disorders / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology; D016022:Case-Control Studies; D005556:Form Perception / Q000502:physiology; D005625:Frontal Lobe / Q000502:physiology / Q000503:physiopathology; D006801:Humans; D008297:Male; D008569:Memory Disorders / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology*; D008570:Memory, Short-Term / Q000502:physiology*; D011939:Mental Recall / Q000502:physiology; D008875:Middle Aged; D010364:Pattern Recognition, Visual / Q000502:physiology*; D011334:Proactive Inhibition; D011930:Reaction Time / Q000502:physiology; D012016:Reference Values; D012660:Semantics; D012691:Serial Learning / Q000502:physiology*; D020521:Stroke / Q000150:complications / Q000503:physiopathology