Effect of chinese herbal medicine "saiko-keishi-to" on transmembrane ionic current of snail neurons.
The effect of the Chinese herbal medicine "Saiko-Keishi-To" (SK) on transmembrane ionic current was examined to elucidate the mechanism of the anticonvulsant action of SK. SK caused a decrease in tramsmembarane sodium, calcium and potassium current. SK was also found to inhibit the negative resistance characteristics in an experiment using a voltage clamp with triangular command.
Sugaya
A
A
Faculty of Pharmaceutical Sciences, Josai University Keyakidai, Sakado-shi, Saitama-ken, Japan.
Tsuda
T
T
Yasuda
K
K
Sugaya
E
E