Mycoplasma pneumoniae and atypical Stevens-Johnson syndrome: a case series.
Mycoplasma pneumoniae is a common cause of community-acquired respiratory illness in the adolescent population. Stevens-Johnson syndrome is an extrapulmonary manifestation that has been associated with M. pneumoniae infections. Three adolescent males presented within a 1-month period with M. pneumoniae respiratory illnesses and severe mucositis but without the classic rash typical of Stevens-Johnson. Diagnosis was facilitated by the use of a polymerase chain reaction-based assay. This case series highlights the potential for M. pneumoniae-associated Stevens-Johnson syndrome to occur without rash and supports the use of polymerase chain reaction for early diagnosis.
Ravin
Karen A
KA
Department of Pediatrics, Division of Infectious Diseases, Children's Hospital of Pittsburgh, 3705 Fifth Ave, Pittsburgh, PA 15213-2583, USA. karen.ravin@chp.edu
Rappaport
Lara D
LD
Zuckerbraun
Noel S
NS
Wadowsky
Robert M
RM
Wald
Ellen R
ER
Michaels
Marian M
MM
D000293:Adolescent; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002648:Child; D004269:DNA, Bacterial / Q000032:analysis; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D009061:Mouth Mucosa / Q000382:microbiology / Q000473:pathology; D052016:Mucositis / Q000188:drug therapy / Q000382:microbiology* / Q000503:physiopathology; D009177:Mycoplasma pneumoniae / Q000302:isolation & purification*; D016133:Polymerase Chain Reaction; D018570:Risk Assessment; D012494:Sampling Studies; D012720:Severity of Illness Index; D013262:Stevens-Johnson Syndrome / Q000188:drug therapy / Q000382:microbiology* / Q000503:physiopathology*; D016896:Treatment Outcome
D000900:Anti-Bacterial Agents; D004269:DNA, Bacterial