title: [Investigation of intestinal bacterial translocation in 78 patients with cirrhosis after liver transplantation].
abstract: OBJECTIVE
  To investigate the prevalence and associated risk factors of bacterial translocation (BT) in patients with cirrhosis after liver transplantation and analyze the effect of BT on bacterial infection after the surgery.
  
  
  METHODS
  Mesenteric lymph nodes (MLN), portal vein blood, and peripheral blood were collected during the liver transplantation for microbiological culture from 78 patients with cirrhosis. And meanwhile, all related clinical data were analyzed to investigate the risk factors of BT and its relationship with post-liver transplantation infections.
  
  
  RESULTS
  BT was occurred in 8 of 78 cirrhotic patients (10.3%) and positive-rate of MLN culture was 5/8. Gram-negative aerobic bacillus was the main causative bacterium of BT (5/9), followed by Gram-positive aerobic enterococcus (22.2%, 2/9). Total bilirubin level in patients with BT was significantly higher than that in patients without BT.
  
  
  CONCLUSIONS
  It suggests that hyperbilirubinemia is the only risk factor for BT, and BT is associated with an increased infectious rate after liver transplantation.
authors.affiliation: Department of Infectious Diseases, the First Affiliated Hospital, Zhejiang University, Hangzhou, China.
authors.forename: Zhong-Wen
authors.initials: ZW
authors.lastname: Wu
authors.forename: Kai-Jin
authors.initials: KJ
authors.lastname: Xu
authors.forename: Lan-Juan
authors.initials: LJ
authors.lastname: Li
authors.forename: Jian
authors.initials: J
authors.lastname: Zuo
authors.forename: Ji-Fang
authors.initials: JF
authors.lastname: Sheng
authors.forename: Shu-Sen
authors.initials: SS
authors.lastname: Zheng
authors.forename: Ting-Bo
authors.initials: TB
authors.lastname: Liang
authors.forename: Yan
authors.initials: Y
authors.lastname: Shen
authors.forename: Wei-Lin
authors.initials: WL
authors.lastname: Wang
authors.forename: Min
authors.initials: M
authors.lastname: Zhang
mesh_terms: D000328:Adult; D001424:Bacterial Infections / Q000097:blood / Q000209:etiology; D018988:Bacterial Translocation; D005260:Female; D006801:Humans; D007422:Intestines / Q000382:microbiology*; D008103:Liver Cirrhosis / Q000382:microbiology* / Q000601:surgery; D016031:Liver Transplantation / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D010538:Peritonitis / Q000209:etiology; D011183:Postoperative Complications / Q000209:etiology / Q000382:microbiology; D012307:Risk Factors