title: Towards optimization of probe placement for radio-frequency ablation.
abstract: We present a model for the optimal placement of mono- and bipolar probes in radio-frequency (RF) ablation. The model is based on a numerical computation of the probe's electric potential and of the steady state of the heat distribution during RF ablation. The optimization is performed by minimizing a temperature based objective functional under these constraining equations. The paper discusses the discretization and implementation of the approach. Finally, applications of the optimization to artificial data and a comparison to a real RF ablation are presented.
authors.affiliation: CeVis-Center for Complex Systems and Visualization, University of Bremen, Germany.
authors.forename: Inga
authors.initials: I
authors.lastname: Altrogge
authors.forename: Tim
authors.initials: T
authors.lastname: Kröger
authors.forename: Tobias
authors.initials: T
authors.lastname: Preusser
authors.forename: Christof
authors.initials: C
authors.lastname: Büskens
authors.forename: Philippe L
authors.initials: PL
authors.lastname: Pereira
authors.forename: Diethard
authors.initials: D
authors.lastname: Schmidt
authors.forename: Andreas
authors.initials: A
authors.lastname: Weihusen
authors.forename: Heinz-Otto
authors.initials: HO
authors.lastname: Peitgen
mesh_terms: D000465:Algorithms; D017115:Catheter Ablation / Q000379:methods*; D003198:Computer Simulation; D006801:Humans; D008954:Models, Biological; D009369:Neoplasms / Q000601:surgery*; D013813:Therapy, Computer-Assisted / Q000379:methods*; D013817:Thermography / Q000379:methods*