title: [Clinical experience of combined oral contraceptives of low doses in Mexico].
abstract: BACKGROUND
  The combined oral contraceptives are one of the most prescribed medicines. Across the years they have given to more than 60 million women of the whole world a suitable method for the highly reliable and effective natal control. The oral contraceptives are different from other medicines; principally they are not in use for controlling any disease and have the potential of giving advantages.
  
  
  OBJECTIVE
  To evaluate the control of the cycle, tolerability and acceptance of an oral contraceptive of ultralow dose with gestodene (60 microg) and ethinylestradiol (15 microg) in a population of healthy women from 18 to 35 years.
  
  
  METHODS
  The study included adult healthy women, all the users signed assent of informed before being included to the study and of the beginning of any procedure in agreement with the declarations of Helsinki and its amendments. Descriptive statistics was used for the demographic information and the comparison between the initial and final visits of the variables of efficiency. There was used the test (Proof) of ranges of Wilcoxon's sign for related samples.
  
  
  RESULTS
  There were included 113 women. The average of age was 26.08 years (SD = 4.43), weight of 62.02 kg (SD = 11.13) and height of 159.20 cm (SD = 6.06). The distribution in four centers was: 32 in the University Hospital (Monterrey), 21 in the Country 2000 (Guadalajara), 30 in in the Medical Center La Mora (Aguascalientes) and 30 in Perinatology National Institute (Mexico City).
  
  
  CONCLUSIONS
  The contraceptive efficiency of the combination of 15 microg of ethinylestradiol and 60 microg of gestodene has been demonstrated in previous studies. This study ratifies the international results of efficiency and tolerability.
authors.affiliation: Facultad de Medecina, Hospital Universitario Eleuterio Gonzalez, Monterrey, Neuvo, León.
authors.forename: Donato
authors.initials: D
authors.lastname: Saldívar Rodríguez
authors.forename: Juanita
authors.initials: J
authors.lastname: Vázquez
authors.forename: Roger
authors.initials: R
authors.lastname: Lara
authors.forename: Carlos
authors.initials: C
authors.lastname: Ramos
authors.forename: Josefina
authors.initials: J
authors.lastname: Lira
authors.forename: Ever
authors.initials: E
authors.lastname: Rodríguez
authors.forename: Jorge
authors.initials: J
authors.lastname: Romo
mesh_terms: D000293:Adolescent; D000328:Adult; D003277:Contraceptives, Oral, Combined / Q000008:administration & dosage* / Q000009:adverse effects; D005260:Female; D006801:Humans; D008800:Mexico
chemical_list: D003277:Contraceptives, Oral, Combined