Gyriform differentiation in medulloblastoma - a radiological predictor of histology.
Medulloblastoma with extensive nodularity (MBEN) is a variant with an apparently favorable outcome. The authors describe a 2-month-old child with MBEN who had a characteristic gyriform morphology on MR imaging preoperatively and was found to have local metastasis into the adjoining cerebellum on histopathological examination. This case illustrates that histological subtyping may be possible based on the imaging morphology in selected tumors, which may have a bearing on the management of these tumors.
Agrawal
Deepak
D
Department of Pediatric Surgery, Division of Pediatric Neurosurgery, University of British Columbia, Canada. ved@vsnl.com
Singhal
Ashutosh
A
Hendson
Glenda
G
Durity
Felix A
FA
D002471:Cell Transformation, Neoplastic / Q000473:pathology*; D002528:Cerebellar Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D002531:Cerebellum / Q000473:pathology / Q000601:surgery; D003388:Cranial Fossa, Posterior / Q000473:pathology / Q000601:surgery; D005260:Female; D006801:Humans; D006849:Hydrocephalus / Q000175:diagnosis / Q000473:pathology / Q000601:surgery; D007223:Infant; D008279:Magnetic Resonance Imaging; D008527:Medulloblastoma / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D009361:Neoplasm Invasiveness; D013346:Subarachnoid Space / Q000473:pathology / Q000601:surgery; D014057:Tomography, X-Ray Computed; D014464:Ultrasonic Therapy