title: Incidental diagnosis of a PSA-negative prostate cancer by 18FDG PET/CT in a patient with hypopharyngeal cancer.
abstract: Diagnosis of prostate cancer (PC) still remains critical as non-invasive screening with prostate specific-antigen (PSA) lacks to indicate malignancy of the prostate in some cases. Recent research has shown that clinically meaningful PC can develop in patients with a PSA value <4 ng/ml, frequently defined as upper limit of normal serum PSA levels. Furthermore, both morphological (computed tomography (CT), magnetic resonance imaging, transrectal ultrasound) and functional imaging with (18)fluorodeoxyglucose positron emission tomography (FDG-PET) are associated with several limitations for primary diagnosis of PC. We report a case of an incidentally diagnosed PSA-negative PC by (18)FDG PET/CT in a patient with a previous diagnosis of a hypopharyngeal cancer.
authors.affiliation: Department of Nuclear Medicine, University of Bonn, Sigmund-Freud-Strasse 25, Bonn 53105, Germany. jan.bucerius@ukb.uni-bonn.de
authors.forename: J
authors.initials: J
authors.lastname: Bucerius
authors.forename: H
authors.initials: H
authors.lastname: Ahmadzadehfar
authors.forename: N
authors.initials: N
authors.lastname: Hortling
authors.forename: A Y
authors.initials: AY
authors.lastname: Joe
authors.forename: H
authors.initials: H
authors.lastname: Palmedo
authors.forename: H-J
authors.initials: HJ
authors.lastname: Biersack
mesh_terms: D000230:Adenocarcinoma / Q000097:blood / Q000000981:diagnostic imaging*; D019788:Fluorodeoxyglucose F18; D006801:Humans; D007012:Hypopharyngeal Neoplasms / Q000000981:diagnostic imaging*; D033162:Incidental Findings; D008297:Male; D008875:Middle Aged; D016609:Neoplasms, Second Primary / Q000097:blood / Q000175:diagnosis*; D049268:Positron-Emission Tomography; D017430:Prostate-Specific Antigen / Q000097:blood*; D011471:Prostatic Neoplasms / Q000097:blood / Q000000981:diagnostic imaging*; D019275:Radiopharmaceuticals; D014057:Tomography, X-Ray Computed
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18; D017430:Prostate-Specific Antigen