title: Multiple gastrointestinal stromal tumors in neurofibromatosis type 1 treated with laparoscopic surgery.
abstract: Gastrointestinal stromal tumors (GISTs) have been reported to occasionally occur in patients with neurofibromatosis type 1 (NF-1), and many cases have had multiple lesions predominantly involving the small intestine. We report herein a case of multiple GISTs associated with NF-1 from whom laparoscopic surgery was beneficial. In a 79-year-old female admitted with anemia and melena, the abdominal computed tomography revealed a tumor arising from the small intestine. Laparoscopic surgery was performed, and another small tumor was revealed during laparoscopic observation. Extracorporeal partial and wedge resection of the small intestine were undertaken. Both lesions were diagnosed as typical GISTs of low risk. Laparoscopic surgery would be useful for examination and a minimally invasive approach to tumors of the small intestine, especially on cases with the possibility of multiple tumors.
authors.affiliation: Department of Surgery, Okayama Red Cross General Hospital, Okayama 700-8607, Japan. kazu.tsukuda@nifty.com
authors.forename: Kazunori
authors.initials: K
authors.lastname: Tsukuda
authors.forename: Eiji
authors.initials: E
authors.lastname: Ikeda
authors.forename: Shoji
authors.initials: S
authors.lastname: Takagi
authors.forename: Takayoshi
authors.initials: T
authors.lastname: Miyake
authors.forename: Takayuki
authors.initials: T
authors.lastname: Muraoka
authors.forename: Keitaro
authors.initials: K
authors.lastname: Watanabe
authors.forename: Ryuji
authors.initials: R
authors.lastname: Hirai
authors.forename: Shigeharu
authors.initials: S
authors.lastname: Moriyama
authors.forename: Sugato
authors.initials: S
authors.lastname: Nawa
authors.forename: Tadayoshi
authors.initials: T
authors.lastname: Kunitomo
authors.forename: Hisashi
authors.initials: H
authors.lastname: Tsuji
mesh_terms: D000368:Aged; D013505:Digestive System Surgical Procedures / Q000379:methods*; D005260:Female; D046152:Gastrointestinal Stromal Tumors / Q000150:complications / Q000175:diagnosis / Q000601:surgery*; D006801:Humans; D007078:Ileal Neoplasms / Q000150:complications / Q000175:diagnosis / Q000601:surgery*; D033162:Incidental Findings; D010535:Laparoscopy; D009456:Neurofibromatosis 1 / Q000150:complications*; D011860:Radiography, Abdominal; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome