title: Clinical efficacy of percutaneous renal revascularization with stent placement in atherosclerotic renovascular disease.
abstract: OBJECTIVE
  To evaluate the clinical efficacy of percutaneous renal revascularization with stenting to control hypertension and preserve/restore renal function in patients with atherosclerotic renovascular disease.
  
  
  METHODS
  From May/1999 to October/2003, 46 patients with atherosclerotic renal artery stenosis (ARAS) underwent revascularization with stenting. The indication for the procedure was hypertension control and/or renal function preservation/restoration. Clinical characteristics: age range: 33-84 years (median = 58.5 +/-10.7), males: 26 (56.5%), 4 (10%) patients with diabetes mellitus, 21 (46%) patients with coronary artery disease, creatinine <2.0mg/dl: 39 (64%), 6 patients (14%) with congestive heart failure, 20 (43%) patients with ostial stenosis and 15 (33%) patients with bilateral stenosis. Hypertension control was evaluated by the number of drugs used before the procedure and at follow-up (FU) and by blood pressure (BP) measurement.
  
  
  RESULTS
  The minimum follow-up was 7 months (range of 7-52, median: 23, mean: 24.2 +/- 15.2). There were no major complications. No patient experience any cardiovascular event. There was only one non-cadiac death (2%) and one technical failure in the treatment(2%). There was no serious complication in the procedure. None of the patients presented cardiovascular events. The renal function improved or stabilized in 32 patients (82%) and worsened in 4 (10%). The BP control improved in 19/44 (43,8%) patients and worsened / stabilized in 6 patients (14%).
  
  
  CONCLUSIONS
  Angioplasty with renal artery stenting for ARAS showed to be an effective treatment strategy to restore and preserve renal function and to control blood pressure.
authors.affiliation: Hospital do Rim e Hipertensão, Fundação Oswaldo Ramos, São Paulo, SP, Brazil. jan_goncalves@uol.com.br
authors.forename: Janaína Andréa Altemar
authors.initials: JA
authors.lastname: Gonçalves
authors.forename: Jorge Eduardo
authors.initials: JE
authors.lastname: Amorim
authors.forename: Milton Macedo
authors.initials: MM
authors.lastname: Soares Neto
authors.forename: Artur Beltrame
authors.initials: AB
authors.lastname: Ribeiro
authors.forename: Valter Correa
authors.initials: VC
authors.lastname: Lima
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000800:Angioplasty, Balloon; D050197:Atherosclerosis / Q000150:complications / Q000628:therapy*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006978:Hypertension, Renovascular / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012078:Renal Artery Obstruction / Q000209:etiology / Q000628:therapy*; D015607:Stents; D016896:Treatment Outcome