title: [Burden of mortality associated to physical inactivity in Bogota, Colombia].
abstract: Estimates of the burden of mortality associated to physical inactivity (PI) have not been quantified for large urban centers located in developing countries.
  
  
  OBJECTIVE
  To estimate the burden of mortality due to six chronic diseases (CDZ) associated to PI and the number of potentially preventable deaths associated to reductions in the prevalence of PI.
  
  
  METHODS
  PI exposure prevalence obtained via population surveys was linked to mortality data registered during 2002 among adult (> 45 y) Bogotá residents. The strength of association between PI and disease-specific mortality was obtained from the literature. Population attributable risk (PAR) was used to calculate the CDZ mortality attributable to PI and to estimate the number of potentially preventable deaths associated to a 30 % reduction in the prevalence of PI.
  
  
  RESULTS
  A 53,2 % PI exposure prevalence was associated to a PAR of 19,3 % for coronary artery disease, 24,2 % for stroke, 13,8 % for arterial hypertension, 21 % for Diabetes Mellitus, 17,9 % for colon cancer and 14,2 % for breast cancer. An estimated 7,6 % of all-cause mortality and 20,1 % of CDZ mortality could be attributed to PI. An estimated 5% of the CDZ mortality could be prevented if PI prevalence is reduced by 30 %.
  
  
  CONCLUSIONS
  Conservative estimates indicate that a considerable proportion of deaths due to highly prevalent CDZ could be attributed to PI. Strategies to reduce the prevalence of PI in Bogotá could lead to progressive reductions in the burden of CDZ mortality.
authors.affiliation: Departamento de Ciencias del Ejercicio, Facultad de Salud Publica, Universidad de Carolina del Sur, Columbia, SC 29208, USA. lobelo@mailbox.sc.edu
authors.forename: Felipe
authors.initials: F
authors.lastname: Lobelo
authors.forename: Rusell
authors.initials: R
authors.lastname: Pate
authors.forename: Diana
authors.initials: D
authors.lastname: Parra
authors.forename: John
authors.initials: J
authors.lastname: Duperly
authors.forename: Michael
authors.initials: M
authors.lastname: Pratt
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001161:Arteriosclerosis / Q000401:mortality; D001943:Breast Neoplasms / Q000401:mortality; D003105:Colombia; D003110:Colonic Neoplasms / Q000401:mortality; D003327:Coronary Disease / Q000401:mortality; D003920:Diabetes Mellitus / Q000401:mortality; D004198:Disease Susceptibility; D005260:Female; D006801:Humans; D006973:Hypertension / Q000401:mortality; D008019:Life Style; D008297:Male; D008875:Middle Aged; D009026:Mortality; D009043:Motor Activity; D015995:Prevalence; D040242:Risk Reduction Behavior; D020521:Stroke / Q000401:mortality; D014505:Urban Population / Q000706:statistics & numerical data