title: [The suitability of hyaluronic acid in the therapy of deep upper lid sulcus in the anophthalmic orbit].
abstract: BACKGROUND
  For correcting deep persisting upper lid sulcus in cases of enucleation or evisceration, a subperiostal implant can be used to lift the entire contents of the orbit, or dermis fat can be implanted into the lid. However, there is no optimal surgical procedure in these cases.
  
  
  METHODS
  Five patients showing a deep, persisting, upper lid sulcus were treated with hyaluronic acid. The resorption of the acid was documented by photography every 4 weeks. Four out of the five patients did well; one patient lost the acid completely after 1-2 days and showed signs of inflammation. The time for resorption to occur varied from 4.5 to 11 months. Two patients showed better moistening of the prostheses.
  
  
  CONCLUSIONS
  This pilot study shows that cross-linked hyaluronic acid can be used for the temporary treatment of the deep upper lid sulcus. Further studies should be carried out using a larger number of patients in order to obtain more detailed information.
authors.affiliation: Augenklinik des St. Josefs-Hospital, Universitätsklinik der Universität Witten/Herdecke, Hagen, Deutschland. meyer-ruesenberg@kkh-hagen.de
authors.forename: H-W
authors.initials: HW
authors.lastname: Meyer-Rüsenberg
mesh_terms: D000328:Adult; D000368:Aged; D005141:Eyelid Diseases / Q000188:drug therapy*; D005143:Eyelids / Q000002:abnormalities* / Q000187:drug effects*; D005260:Female; D006801:Humans; D006820:Hyaluronic Acid / Q000008:administration & dosage*; D008297:Male; D008875:Middle Aged; D010865:Pilot Projects; D016896:Treatment Outcome
chemical_list: D006820:Hyaluronic Acid