COP sets TRAPP for vesicles.
Intracellular transport vesicles identify their destination by a poorly understood process termed tethering. Recent work shows that in addition to its role in membrane-cargo selection, the COPII vesicle coat recruits TRAPPI, a cytosolic protein complex required for vesicle tethering.
Haas
Alexander K
AK
Department of Cell Biology, Max-Planck-Institute of Biochemistry, Martinsried 82152, Germany.
Barr
Francis A
FA
D000818:Animals; D022181:COP-Coated Vesicles / Q000378:metabolism*; D004721:Endoplasmic Reticulum / Q000378:metabolism / Q000648:ultrastructure; D006056:Golgi Apparatus / Q000378:metabolism / Q000648:ultrastructure; D006801:Humans; D007425:Intracellular Membranes / Q000378:metabolism* / Q000648:ultrastructure; D008565:Membrane Proteins / Q000378:metabolism*; D015398:Signal Transduction / Q000502:physiology; D022161:Transport Vesicles / Q000378:metabolism* / Q000648:ultrastructure; D033921:Vesicular Transport Proteins / Q000378:metabolism*; D015003:Yeasts / Q000378:metabolism; D020691:rab GTP-Binding Proteins / Q000378:metabolism*
D008565:Membrane Proteins; D033921:Vesicular Transport Proteins; C406327:transport protein particle, TRAPP; D020691:rab GTP-Binding Proteins