title: Differentiating bipolar disorder from depression in primary care.
abstract: Because patients with bipolar disorder spend more time in the depressed phase than in the manic phase, many receive an incorrect diagnosis of unipolar major depression and receive inadequate or improper treatment for it, leading to a dramatically increased risk of morbidity and suicide. Greater diagnostic accuracy is needed.
authors.affiliation: Bipolar Disorders Research Unit, Department of Psychiatry and Psychology, Cleveland Clinic, OH 44195, USA. muzinad@ccf.org
authors.forename: David J
authors.initials: DJ
authors.lastname: Muzina
authors.forename: Elisa
authors.initials: E
authors.lastname: Colangelo
authors.forename: J Sloan
authors.initials: JS
authors.lastname: Manning
authors.forename: Joseph R
authors.initials: JR
authors.lastname: Calabrese
mesh_terms: D001714:Bipolar Disorder / Q000175:diagnosis* / Q000188:drug therapy / Q000503:physiopathology; D003863:Depression / Q000175:diagnosis* / Q000188:drug therapy / Q000503:physiopathology; D003865:Major Depressive Disorder / Q000175:diagnosis*; D003937:Diagnosis, Differential; D006801:Humans; D000077213:Lamotrigine; D018020:Lithium Compounds / Q000627:therapeutic use; D010821:Physicians, Family; D011320:Primary Health Care; D014227:Triazines / Q000627:therapeutic use; D014635:Valproic Acid / Q000627:therapeutic use
chemical_list: D018020:Lithium Compounds; D014227:Triazines; D014635:Valproic Acid; D000077213:Lamotrigine