Kounis syndrome secondary to amoxicillin/clavulanic acid use.
Myocardial injury and acute coronary syndrome have been rarely associated with amoxicillin/clavulanic acid intake. The responsible pathogenetic mechanism is described by an amplified mast cell degranulation inducing coronary artery spasm and/or acute myocardial infarction in susceptible individuals which is called Kounis syndrome. We report here a case of Kounis syndrome presented with acute coronary syndrome due to amoxicillin/clavulanic acid use. All other etiologies, including ischemic reinfarction were appropriately ruled out.
Tavil
Yusuf
Y
Turfan
Murat
M
Türkoğlu
Sedat
S
Abaci
Adnan
A
D054058:Acute Coronary Syndrome / Q000139:chemically induced* / Q000175:diagnosis; D019980:Amoxicillin-Potassium Clavulanate Combination / Q000009:adverse effects*; D000787:Angina Pectoris / Q000139:chemically induced*; D017023:Coronary Angiography; D004562:Electrocardiography; D006801:Humans; D008297:Male; D008875:Middle Aged; D013577:Syndrome
D019980:Amoxicillin-Potassium Clavulanate Combination