Simvastatin intensifies heart rate depression after metoprolol and atropine administration in normocholesterolemic rats.
Owczarek
Jacek
J
Deparment of Biopharmacy, Medical University of Lódź, Poland. jacow2@tlen.pl
Jasińska
Magdalena
M
Wejman
Irena
I
Baryś
Magdalena
M
Orszulak-Michalak
Daria
D
D000818:Animals; D000924:Anticholesteremic Agents / Q000494:pharmacology; D000959:Antihypertensive Agents / Q000494:pharmacology; D001285:Atropine / Q000008:administration & dosage; D001341:Autonomic Nervous System / Q000187:drug effects; D001794:Blood Pressure / Q000187:drug effects; D002784:Cholesterol / Q000097:blood; D004359:Drug Therapy, Combination; D006339:Heart Rate / Q000187:drug effects*; D008790:Metoprolol / Q000008:administration & dosage; D051381:Rats; D019821:Simvastatin / Q000008:administration & dosage / Q000494:pharmacology*
D000924:Anticholesteremic Agents; D000959:Antihypertensive Agents; D001285:Atropine; D002784:Cholesterol; D019821:Simvastatin; D008790:Metoprolol