Investigating cortical variability using a generic gyral model.
In this paper, we present a systematic investigation of the variability of the human cortical folding using a generic gyral model (GGM). The GGM consists of a fixed number of vertices that can be registered non-linearly to an individual anatomy so that for each individual we have a clearly defined set of landmarks that is spread across the cortex. This allows us to obtain a regionalized estimation of intersubject variability. Since the GGM is stratified into different levels of depth, it also allows us to estimate variability as a function of depth. As another application of a polygonal line representation underlying the generic gyral model, we present a cortical parcellation scheme that can be used to regionalize cortical measurements.
Lohmann
Gabriele
G
Max-Planck-Institute for Human Cognitive and Brain Sciences, Leipzig, Germany.
von Cramon
D Yves
DY
Colchester
Alan C F
AC
D000465:Algorithms; D001185:Artificial Intelligence; D002540:Cerebral Cortex / Q000033:anatomy & histology*; D003198:Computer Simulation; D007089:Image Enhancement / Q000379:methods; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D021621:Imaging, Three-Dimensional / Q000379:methods*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008953:Models, Anatomic; D008954:Models, Biological; D015233:Models, Statistical; D010363:Pattern Recognition, Automated / Q000379:methods*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity