title: Donepezil in the treatment of musical hallucinations.
abstract: Musical hallucinations (MH) typically occur among elderly individuals and are associated with hearing impairment. The authors describe a patient with features of typical MH who was successfully treated with donepezil, a cholinesterase inhibitor, as a combination therapy and who has not shown any subsequent cognitive decline for approximately 5 years. The efficacy of donepezil in this patient indicates that age-dependent dysfunction of cholinergic neurons might be related to the development of MH.
authors.affiliation: Department of Psychiatry and Behavioral Science, Osaka University Graduate School of Medicine, Osaka, Japan. ukai@wakayama-med.ac.jp
authors.forename: Satoshi
authors.initials: S
authors.lastname: Ukai
authors.forename: Masakiyo
authors.initials: M
authors.lastname: Yamamoto
authors.forename: Michio
authors.initials: M
authors.lastname: Tanaka
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Shinosaki
authors.forename: Masatoshi
authors.initials: M
authors.lastname: Takeda
mesh_terms: D000369:Aged, 80 and over; D000077265:Donepezil; D004359:Drug Therapy, Combination; D005260:Female; D006212:Hallucinations / Q000188:drug therapy* / Q000523:psychology; D006311:Hearing Disorders / Q000150:complications; D006801:Humans; D007189:Indans / Q000627:therapeutic use*; D009146:Music / Q000523:psychology*; D018697:Nootropic Agents / Q000627:therapeutic use*; D010880:Piperidines / Q000627:therapeutic use*
chemical_list: D007189:Indans; D018697:Nootropic Agents; D010880:Piperidines; D000077265:Donepezil