title: Are perinatal and maternal outcomes different during expectant management of severe preeclampsia in the presence of intrauterine growth restriction?
abstract: OBJECTIVE
  The purpose of this study was to compare perinatal and maternal outcomes in women with singleton pregnancies and severe preeclampsia (SPE) expectantly managed at 24-33 weeks' gestation (wk) that resulted at birth in severe intrauterine growth restriction (SIUGR, < 5th percentile) to those without SIUGR.
  
  
  METHODS
  Two hundred thirty-nine women undelivered after antenatal steroids were expectantly managed. Perinatal and maternal outcomes were analyzed according to fetal growth status. Students t-test, chi-square test, logistic regression analysis, and odds ratio were calculated.
  
  
  RESULTS
  Fifty-eight pregnancies resulted in an SIUGR neonate. Median latency periods (5 vs 5 d) and delivery gestational ages (30.6 vs 30.3 wk) were similar in the 2 groups. Controlling for gestational age at delivery, only fetal death remained associated with SIUGR (OR: 6.4; 95% CI 1.05-39.35, P = .04). Maternal outcomes were similar in the 2 groups.
  
  
  CONCLUSIONS
  In severe preeclamptic women at 24-33 weeks, SIUGR is associated with increased risk of fetal death but does not affect maternal complications.
authors.affiliation: Department of Obstetrics and Gynecology, University of Paris XII, Créteil, Paris, France. bhaddad@chicreteil.fr
authors.forename: Bassam
authors.initials: B
authors.lastname: Haddad
authors.forename: Gilles
authors.initials: G
authors.lastname: Kayem
authors.forename: Stephanie
authors.initials: S
authors.lastname: Deis
authors.forename: Baha M
authors.initials: BM
authors.lastname: Sibai
mesh_terms: D000328:Adult; D005260:Female; D005313:Fetal Death; D005317:Fetal Growth Retardation; D006801:Humans; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000453:epidemiology; D008875:Middle Aged; D011225:Pre-Eclampsia / Q000628:therapy*; D011247:Pregnancy; D011256:Pregnancy Outcome; D012720:Severity of Illness Index