title: Comparison of six-minute walking tests conducted with and without supplemental oxygen in patients with chronic obstructive pulmonary disease and exercise-induced oxygen desaturation.
abstract: BACKGROUND
  There are contradictory reports in the literature on the effects of supplemental oxygen administered before or after exercise tests. In light of this, we compared the results of 6-minute walking tests performed in room-air conditions (A6MWT) and with supplemental oxygen (O6MWT) in patients with chronic obstructive pulmonary disease (COPD) and exercise-induced oxygen desaturation.
  
  
  METHODS
  Thirty-one patients with COPD were included in the study. The A6MWT and O6MWT were performed in randomized order on each patient. During the tests, severity of dyspnea and tiring of the leg were evaluated by the Modified Borg Scale. Heart rate and pulsed oxygen saturation and blood pressure were measured by pulse oximeter.
  
  
  RESULTS
  Walking distance was longer with the O6MWT than with the A6MWT (P=0.001). The O6MWT resulted in a smaller increase in dyspnea, leg fatigue, and heart rate and a smaller drop in pulsed saturation than the A6MWT (P<0.05). The walking distance with the O6MWT correlated with respiratory function and hemodynamic parameters (P<0.05).
  
  
  CONCLUSIONS
  The O6MWT, which produced less hemodynamic stress and was safer than the A6MWT, might provide more accurate information on exercise limitation for patients with COPD. These results suggest that the O6MWT can be used as a standard walking exercise test for patients with COPD and exercise-induced oxygen desaturation.
authors.affiliation: Doluz Eylul University, School of Physical Therapy and Rehabillitation, Izmir, Turkey. sevgi.ozalevli@deu.edu.tr
authors.forename: Sevgi
authors.initials: S
authors.lastname: Ozalevli
authors.forename: Ayse
authors.initials: A
authors.lastname: Ozden
authors.forename: Zeliha
authors.initials: Z
authors.lastname: Gocen
authors.forename: Arif Hikmet
authors.initials: AH
authors.lastname: Cimrin
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D005080:Exercise Test / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010092:Oximetry; D010100:Oxygen / Q000378:metabolism*; D010102:Oxygen Inhalation Therapy; D029424:Pulmonary Disease, Chronic Obstructive / Q000503:physiopathology / Q000628:therapy*; D016138:Walking / Q000502:physiology
chemical_list: D010100:Oxygen