[Biological effects and their applications in medicine of pulsed electric fields].
Pulsed electric fields can induce various kinds of biological effects that are essentially different from the normal electric fields, especially the interactions of Nanosecond Pulsed electric field (nsPEF) with cells. The biological effects of different pulsed electric fields on cell membranes, cytoplasmic matrixes, cell growth are introduced in this paper. Based on these effects, some applications of pulsed electric fields in cancer therapy, gene therapy, and delivery of drugs are reviewed in details.
Huang
Hua
H
Key Laboratory for Biomnechanics & Tissue Engineering of the State Ministry of Education, College of Bioengineering, Chongqing University, Chongqing 400044, China.
Song
Guanbin
G
Wang
Guixue
G
Sun
Caixin
C
D002462:Cell Membrane / Q000378:metabolism / Q000528:radiation effects*; D002468:Cell Physiological Phenomena; D004574:Electromagnetic Fields; D004594:Electrophysiology; D018274:Electroporation; D015316:Genetic Therapy / Q000379:methods; D009369:Neoplasms / Q000628:therapy*