title: The diversity of multi-drug resistance profiles in tetracycline-resistant Vibrio species isolated from coastal sediments and seawater.
abstract: In this study we examined the multi-drug resistance profiles of the tetracycline (TC) resistant genus Vibrio to determine its susceptibility to two beta-lactams, ampicillin (ABPC), and mecillinam (MPC), as well as to macrolide, erythromycin (EM). The results showed various patterns of resistance among strains that were isolated from very close geographical areas during the same year, suggesting diverse patterns of drug resistance in environmental bacteria from this area. In addition, the cross-resistance patterns suggested that the resistance determinants among Vibrio spp. are acquired differently within the sediment and seawater environments.
authors.affiliation: Center for Marine Environmental Studies (CMES), Ehime University, Matsuyama 790-8577, Japan.
authors.forename: Farzana Ashrafi
authors.initials: FA
authors.lastname: Neela
authors.forename: Lisa
authors.initials: L
authors.lastname: Nonaka
authors.forename: Satoru
authors.initials: S
authors.lastname: Suzuki
mesh_terms: D000560:Amdinocillin / Q000494:pharmacology; D000667:Ampicillin / Q000494:pharmacology; D017756:Aquaculture; D024881:Drug Resistance, Bacterial / Q000235:genetics*; D018432:Drug Resistance, Multiple; D004917:Erythromycin / Q000494:pharmacology; D019015:Geologic Sediments / Q000382:microbiology*; D007564:Japan; D008826:Microbial Sensitivity Tests; D012623:Seawater / Q000382:microbiology*; D013753:Tetracycline Resistance / Q000235:genetics*; D014733:Vibrio / Q000187:drug effects* / Q000235:genetics
chemical_list: D004917:Erythromycin; D000667:Ampicillin; D000560:Amdinocillin