Unambiguous NMR spectral assignments of salvinorin A.
The complete assignments of the (1)H and (13)C NMR spectra of the hallucinogenic neoclerodane diterpenoid salvinorin A were determined in three different NMR solvents using HSQC, HMBC and COSY. Solvent systems are described that allow the resolution of all (1)H signals. Virtual coupling was observed for the protons at C-2, C-3 and C-4 in the 600 MHz (1)H spectrum in CDCl(3). The complete assignments of the (1)H and (13)C NMR spectra of salvinorin B are also reported.
Giner
José-Luis
JL
Department of Chemistry, State University of New York ESF, Syracuse, NY 13210, USA. jlginer@syr.edu
Kiemle
David J
DJ
Kutrzeba
Lukasz
L
Zjawiony
Jordan
J
D002236:Carbohydrate Conformation; D004224:Diterpenes / Q000737:chemistry* / Q000302:isolation & purification; D045785:Diterpenes, Clerodane; D006213:Hallucinogens / Q000737:chemistry* / Q000302:isolation & purification; D019906:Nuclear Magnetic Resonance, Biomolecular; D027544:Salvia / Q000737:chemistry
D004224:Diterpenes; D045785:Diterpenes, Clerodane; D006213:Hallucinogens; C090499:salvinorin A