EuSplice: a unified resource for the analysis of splice signals and alternative splicing in eukaryotic genes.
BACKGROUND
Despite increased availability of genome annotation data, a comprehensive resource for in-depth analysis of splice signal distributions and alternative splicing (AS) patterns in eukaryote genomes is still lacking. To meet this need, we have developed EuSplice--a unique splice-centric database which provides reliable splice signal and AS information for 23 eukaryotes.


RESULTS
The EuSplice database contains 95,822 AS events and 2.1 million splice signals associated with over 270,000 protein-coding genes. The intuitive, user-friendly EuSplice web interface has powerful data mining and graphics capabilities for inter-genomic comparative analysis of splice signals, putative cryptic splice sites and AS events. Moreover, the seamless integration of splicing data to extensive gene-specific annotations, such as homolog annotations, functional information, mutations and sequence details makes EuSplice a powerful one-stop information resource for investigating the molecular mechanisms of complex splicing events, disease associations and the evolution of splicing in eukaryotes.


BACKGROUND
http://66.170.16.154/EuSplice.


BACKGROUND
Supplementary tables and figures at Bioinfo online.
Bhasi
Ashwini
A
Department of Human Genetics, Genome Technologies, Inc., 8000 Excelsior Drive, Madison, WI 53717, USA.
Pandey
Ram Vinay
RV
Utharasamy
Suriya Prabha
SP
Senapathy
Periannan
P
D017398:Alternative Splicing; D019295:Computational Biology / Q000379:methods*; D003627:Data Interpretation, Statistical; D030541:Databases, Genetic; D019143:Evolution, Molecular; D005656:Fungal Proteins / Q000235:genetics; D005800:Genes, Fungal; D016678:Genome; D023281:Genomics / Q000379:methods*; D020407:Internet; D008957:Models, Genetic; D012326:RNA Splicing; D012333:RNA, Messenger / Q000378:metabolism; D012984:Software; D014158:Transcription, Genetic
D005656:Fungal Proteins; D012333:RNA, Messenger