title: MR regional perfusion imaging: visualizing functional collateral circulation.
abstract: We applied regional perfusion imaging (RPI), a new arterial spin-labeling MR imaging method that selectively studies regions of the brain perfused by individual carotid and basilar arteries. In a patient with cerebrovascular disease, RPI showed cerebral tissue perfused by pial collateral vessels, thereby demonstrating the relationship between anatomic and functional information, which was lacking in conventional x-ray angiography. RPI may be useful to study functional collateral circulation and hence guide therapy in ischemic disease.
authors.affiliation: Department of Neuroradiology, National Neuroscience Institute, Singapore. tchoyoson_lim@nni.com.sg
authors.forename: C C T
authors.initials: CC
authors.lastname: Lim
authors.forename: E T
authors.initials: ET
authors.lastname: Petersen
authors.forename: I
authors.initials: I
authors.lastname: Ng
authors.forename: P Y K
authors.initials: PY
authors.lastname: Hwang
authors.forename: F
authors.initials: F
authors.lastname: Hui
authors.forename: X
authors.initials: X
authors.lastname: Golay
mesh_terms: D001488:Basilar Artery / Q000473:pathology; D002545:Brain Ischemia / Q000473:pathology* / Q000503:physiopathology; D002339:Carotid Arteries / Q000473:pathology; D002560:Cerebrovascular Circulation; D003097:Collateral Circulation; D038524:Diffusion Magnetic Resonance Imaging; D006801:Humans; D018810:Magnetic Resonance Angiography / Q000379:methods*; D008297:Male; D008875:Middle Aged; D010841:Pia Mater / Q000098:blood supply; D013113:Spin Labels
chemical_list: D013113:Spin Labels