title: [Terpenoid compounds isolated from Ligularia sagitta].
abstract: OBJECTIVE
  To study the chemical constituents of radix and rhizome of Ligularia sagitta.
  
  
  METHODS
  Isolation and purification were carried out on the column chromatography of silica gel and sephadex LH -20. The structures were identified by spectral analysis.
  
  
  RESULTS
  Seven terpenoid compounds were isolated from the radix and rhizome of L. sagitta. Five of them are sesquiterpenoids, the structures were determined as 7alpha-hydroxy-9(10) -ene-1, 8-dioxo-6, 7-dihydrofuranoeremophilane (1), 1p, 10P3-epoxy-6beta, 8 beta-dihydroxy-eremophil7 (11) -en-12, 8alpha-olide (2) , 1-oxo-9-desoxycacalol (3), benzofuranoeremophil-l-ene (4) and bakkenolide (5); other two compounds belong to triterpenoid. 3p, 16P3-dihydroxy-12-oleanen-28-al (6) and lupeol (7).
  
  
  CONCLUSIONS
  Compoundsl-3 and 6 were: isolated from L. sagitta for the first time, and compounds 3 and 6 were obtained from Ligularia for the first time.
authors.affiliation: Department of Pharmacognosy, China Phamraceutical University, Nanjing 210038, China.
authors.forename: Shou-jin
authors.initials: SJ
authors.lastname: Liu
authors.forename: Mian
authors.initials: M
authors.lastname: Zhang
authors.forename: Zheng-tao
authors.initials: ZT
authors.lastname: Wang
authors.forename: Jian-qun
authors.initials: JQ
authors.lastname: Liu
authors.forename: Chao-feng
authors.initials: CF
authors.lastname: Zhang
mesh_terms: D015107:4-Butyrolactone / Q000031:analogs & derivatives / Q000737:chemistry / Q000302:isolation & purification; D019659:Asteraceae / Q000737:chemistry*; D009828:Oleanolic Acid / Q000031:analogs & derivatives* / Q000737:chemistry / Q000302:isolation & purification; D018517:Plant Roots / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D027343:Rhizome / Q000737:chemistry; D012717:Sesquiterpenes / Q000737:chemistry / Q000302:isolation & purification*; D013729:Terpenes / Q000737:chemistry / Q000302:isolation & purification*
chemical_list: C528301:1-oxo-9-desoxycacalol; C528302:3beta,16beta-dihydroxy-12-oleanen-28-al; D012717:Sesquiterpenes; D013729:Terpenes; D009828:Oleanolic Acid; D015107:4-Butyrolactone; C016257:bakkenolide A