title: Point-of-care PSA testing: an evaluation of PSAwatch.
abstract: We present a new quantitative prostate-specific antigen (PSA) assay using a portable, point-of-care test (PSAwatch) and reader system (BioScan) for measuring PSA concentrations in the range from 0.5 to < or =25 microg/l. Blood samples from patients (n=199) were submitted for laboratory PSA and also evaluated using PSAwatch and the BioScan system. PSA concentrations in 188 men were < or =25 microg/l and studied. Correlation between the two methods was good (R(2)=0.88) with a standard error of 1.588. The regression line had a bias of -0.02 at the concentration of 4.00 microg/l. This is the first report of a quantitative, portable, point-of-care PSA test and reader system. PSAwatch may reduce the number of hospital visits for patients with prostate disease.
authors.affiliation: Department of Urology, Wexham Park Hospital, Wexham Street, Slough, Berkshire, UK. omer.karim@mac.com
authors.forename: O
authors.initials: O
authors.lastname: Karim
authors.forename: A
authors.initials: A
authors.lastname: Rao
authors.forename: M
authors.initials: M
authors.lastname: Emberton
authors.forename: D
authors.initials: D
authors.lastname: Cochrane
authors.forename: M
authors.initials: M
authors.lastname: Partridge
authors.forename: P
authors.initials: P
authors.lastname: Edwards
authors.forename: I
authors.initials: I
authors.lastname: Walker
authors.forename: I
authors.initials: I
authors.lastname: Davidson
mesh_terms: D006801:Humans; D008297:Male; D008403:Mass Screening / Q000295:instrumentation* / Q000379:methods*; D019095:Point-of-Care Systems; D017430:Prostate-Specific Antigen / Q000097:blood*; D011471:Prostatic Neoplasms / Q000097:blood / Q000175:diagnosis*; D012680:Sensitivity and Specificity
chemical_list: D017430:Prostate-Specific Antigen