Cat scratch disease during etanercept therapy.
Lymphadenopathy in a patient taking TNFalpha antagonist therapy may indicate lymph node tuberculosis or a hematological malignancy. Although histological evidence of granuloma suggests tuberculosis, many other infections responsible for granulomatous reactions have been reported in patients on TNFalpha antagonist therapy. We report a case of granulomatous lymphadenopathy due to Bartonella henselae in a patient taking etanercept to treat ankylosing spondylitis.
Mathieu
Sylvain
S
Clermont-Ferrand Teaching Hospital, Rheumatology Department, G. Montpied Hospital, Clermont-Ferrand, France. smathieu11@yahoo.fr <smathieu11@yahoo.fr>
Vellin
Jean-François
JF
Poujol
David
D
Ristori
Jean-Michel
JM
Soubrier
Martin
M
D000818:Animals; D000893:Anti-Inflammatory Agents / Q000009:adverse effects*; D018416:Bartonella henselae; D002372:Cat-Scratch Disease / Q000175:diagnosis / Q000382:microbiology* / Q000628:therapy; D002415:Cats; D000068800:Etanercept; D006801:Humans; D007074:Immunoglobulin G / Q000009:adverse effects*; D008206:Lymphatic Diseases / Q000139:chemically induced / Q000175:diagnosis / Q000628:therapy; D008297:Male; D008875:Middle Aged; D009333:Neck; D018124:Receptors, Tumor Necrosis Factor; D013167:Spondylitis, Ankylosing / Q000150:complications / Q000188:drug therapy*; D016896:Treatment Outcome
D000893:Anti-Inflammatory Agents; D007074:Immunoglobulin G; D018124:Receptors, Tumor Necrosis Factor; D000068800:Etanercept