title: ZD6474 induces growth arrest and apoptosis of human leukemia cells, which is enhanced by concomitant use of a novel MEK inhibitor, AZD6244.
authors.forename: C
authors.initials: C
authors.lastname: Nishioka
authors.forename: T
authors.initials: T
authors.lastname: Ikezoe
authors.forename: A
authors.initials: A
authors.lastname: Takeshita
authors.forename: J
authors.initials: J
authors.lastname: Yang
authors.forename: T
authors.initials: T
authors.lastname: Tasaka
authors.forename: Y
authors.initials: Y
authors.lastname: Yang
authors.forename: Y
authors.initials: Y
authors.lastname: Kuwayama
authors.forename: N
authors.initials: N
authors.lastname: Komatsu
authors.forename: K
authors.initials: K
authors.lastname: Togitani
authors.forename: H P
authors.initials: HP
authors.lastname: Koeffler
authors.forename: H
authors.initials: H
authors.lastname: Taguchi
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000494:pharmacology*; D017209:Apoptosis / Q000187:drug effects; D001562:Benzimidazoles / Q000494:pharmacology; D049109:Cell Proliferation / Q000187:drug effects; D004357:Drug Synergism; D006801:Humans; D007938:Leukemia / Q000188:drug therapy*; D008875:Middle Aged; D020929:Mitogen-Activated Protein Kinase Kinases / Q000037:antagonists & inhibitors*; D010880:Piperidines / Q000494:pharmacology; D011799:Quinazolines / Q000494:pharmacology; D014407:Tumor Cells, Cultured
chemical_list: C517975:AZD 6244; D001562:Benzimidazoles; D010880:Piperidines; D011799:Quinazolines; D020929:Mitogen-Activated Protein Kinase Kinases; C452423:vandetanib