title: [A case of surgically treated primary lung cancer with myasthenia gravis].
abstract: A 62-year-old woman, who had received immunosuppressive treatment for myasthenia gravis, was admitted to our hospital for the treatment of a right pulmonary tumor. In October 2003, a chest computed tomography showed a nodule-like lesion in the right lung. Two years later, the lesion was shown to have increased in size, and a right upper lobectomy was performed using video-assisted thoracic surgery. A tumor biopsy showed histological features of bronchioloalveolar carcinoma. It has been reported that malignant tumors occur more frequently in patients with myasthenia gravis with concurrent thymoma. Therefore, such patients need to be followed closely for a long period of time for any possible malignant tumor occurring in different organs. In addition, protection of the bronchial stump may be necessary to prevent a bronchial fistula, because wound healing can be delayed due to immunosuppressive treatment.
authors.affiliation: Department of Respiratory Medicine, Jikei University Kashiwa Hospital.
authors.forename: Masamichi
authors.initials: M
authors.lastname: Takagi
authors.forename: Tadashi
authors.initials: T
authors.lastname: Akiba
mesh_terms: D002282:Adenocarcinoma, Bronchiolo-Alveolar / Q000209:etiology / Q000601:surgery*; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008175:Lung Neoplasms / Q000209:etiology / Q000601:surgery*; D008875:Middle Aged; D009157:Myasthenia Gravis / Q000150:complications* / Q000188:drug therapy / Q000601:surgery; D011013:Pneumonectomy / Q000379:methods*; D011183:Postoperative Complications; D020775:Thoracic Surgery, Video-Assisted; D013934:Thymectomy
chemical_list: D007166:Immunosuppressive Agents