title: [Study on interaction between hypocrellin A and hemoglobin or myoglobin using synchronous fluorescence spectra].
abstract: The effects of hypocrellin A (HA) on the conformational changes of hemoglobin and myoglobin were studied using synchronous fluorescence spectroscopy. The results indicated that HA can change the conformation of these two proteins, leading to the change in the micro-environment of tryptophane and tyrosine residues from hydrophobic environment to hydrophilic environment to different extent.
authors.affiliation: Analysis and Testing Center, Nanjing Normal University, Jiangsu Engineering Research Center of Bio-Medical Function Materials, Nanjing 210097, China.
authors.forename: Xiao-hong
authors.initials: XH
authors.lastname: Wu
authors.forename: Jia-hong
authors.initials: JH
authors.lastname: Zhou
authors.forename: Xiao-tian
authors.initials: XT
authors.lastname: Gu
authors.forename: Shao-hua
authors.initials: SH
authors.lastname: Wei
authors.forename: Yu-ying
authors.initials: YY
authors.lastname: Feng
authors.forename: Tian-hong
authors.initials: TH
authors.lastname: Lu
authors.forename: Xue-song'
authors.initials: XS
authors.lastname: Wang
authors.forename: Bao-wen
authors.initials: BW
authors.lastname: Zhang
mesh_terms: D006454:Hemoglobins / Q000737:chemistry*; D015394:Molecular Structure; D009211:Myoglobin / Q000737:chemistry*; D010569:Perylene / Q000031:analogs & derivatives* / Q000737:chemistry; D019800:Phenol; D011809:Quinones / Q000737:chemistry*; D013050:Spectrometry, Fluorescence
chemical_list: D006454:Hemoglobins; D009211:Myoglobin; D011809:Quinones; D019800:Phenol; D010569:Perylene; C048388:hypocrellin A