[Application of supercritical solution rapid expansion technology in preparation of fine pharmacal particles].
Rapid expansion of supercritical solution (RESS), a new technology, has been developed in the recent years. Fundamental principle of RESS technology used to prepare fine pharmacal particles was summarized in this paper. A brief review of factors which influenced the process of RESS and application of RESS technology were introduced.
Zhang
Zhong-yi
ZY
Department of Pharmacy, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, China. zhang43499@sohu.com
Li
Hong-lei
HL
Lei
Zheng-jie
ZJ
D003460:Crystallization / Q000379:methods; D003692:Delayed-Action Preparations; D049329:Nanostructures; D010316:Particle Size; D004364:Pharmaceutical Preparations / Q000737:chemistry*; D012995:Solubility; D012996:Solutions; D013678:Technology, Pharmaceutical / Q000295:instrumentation* / Q000379:methods*; D013696:Temperature
D003692:Delayed-Action Preparations; D004364:Pharmaceutical Preparations; D012996:Solutions