title: Evaluation of sinus floor elevation using a composite bone graft mixture.
abstract: BACKGROUND
  The performance of implant surgery in the posterior maxilla often poses a challenge due to insufficient available bone. Sinus floor elevation was developed to increase needed vertical height to overcome this problem. The present study described and reported a simple, safe and predictable bone graft mixture for the sinus lifting procedure.
  
  
  METHODS
  Seventy patients were recruited for this study and underwent a sinus lift procedure. All sites were treated with a composite graft of cortical autogenous bone, bovine bone and platelet-rich plasma (PRP). A total of 263 implants (171 Astra Tech and 92 Microdent) were placed either simultaneously or delayed. All sites were clinically and radiographically evaluated 24 months after their prosthetic loading. Biopsy samples were taken from 16 delayed implant placement sites at the time of their implant placement.
  
  
  RESULTS
  A 100% implant success rate was found after 24 months of functioning. Only two Microdent implants failed before loading, which translates to a 99% overall implant success rate. No statistically significant differences were found between simultaneous and delayed implant placement. Image processing revealed 34+/-6.34% vital bone, 49.6+/-6.04% connective tissue and 16.4+/-3.23% remaining Bio-Oss particles. However, the histomorphometric analysis showed that the bovine bone was incorporated into new bone formation.
  
  
  CONCLUSIONS
  The results showed that a composite graft comprised of cortical autogenous bone, bovine bone and PRP mixture can be successfully used for sinus augmentation.
authors.affiliation: Oral Surgery Department, School of Dentistry, University of Granada, Granada, Spain. pgalindo@ugr.es
authors.forename: Pablo
authors.initials: P
authors.lastname: Galindo-Moreno
authors.forename: Gustavo
authors.initials: G
authors.lastname: Avila
authors.forename: Juan Emilio
authors.initials: JE
authors.lastname: Fernández-Barbero
authors.forename: Mariano
authors.initials: M
authors.lastname: Aguilar
authors.forename: Elena
authors.initials: E
authors.lastname: Sánchez-Fernández
authors.forename: Antonio
authors.initials: A
authors.lastname: Cutando
authors.forename: Hom-Lay
authors.initials: HL
authors.lastname: Wang
mesh_terms: D000818:Animals; D018786:Bone Substitutes / Q000627:therapeutic use*; D016025:Bone Transplantation / Q000379:methods*; D002417:Cattle; D003758:Dental Implantation, Endosseous / Q000379:methods; D005260:Female; D006801:Humans; D008297:Male; D008443:Maxillary Sinus / Q000000981:diagnostic imaging / Q000601:surgery*; D008903:Minerals / Q000627:therapeutic use*; D053657:Platelet-Rich Plasma; D011859:Radiography
chemical_list: C077540:Bio-Oss; D018786:Bone Substitutes; D008903:Minerals