Determination of impurities in pharmaceutical preparations containing folic acid.
In the presented study, the HPLC method was used for the determination of impurities (p-aminobenzoic acid and p-aminobenzoyl-L-glutamic acid) in single-component pharmaceutical products containing folic acid. The determination was performed using a spectrophotometric detector at lambda = 269 nm wavelength.
Kłaczkow
Gabriela
G
National Institute of Public Health, 30/34 Chelmska Str., 00-725 Warsaw, Poland.
Anuszewska
Elzbieta L
EL
D010129:4-Aminobenzoic Acid / Q000032:analysis; D002626:Chemistry, Pharmaceutical / Q000379:methods; D002851:Chromatography, High Pressure Liquid; D004340:Drug Contamination; D005492:Folic Acid / Q000627:therapeutic use*; D005971:Glutamates / Q000032:analysis; D013057:Spectrum Analysis
D005971:Glutamates; D005492:Folic Acid; D010129:4-Aminobenzoic Acid