Suspected herpes encephalitis and opercular syndrome in childhood.
Herpes simplex encephalitis is the most common form of sporadic viral encephalitis. It may occur at any age, giving rise to a syndrome with a high morbidity and mortality. Its presentation may be atypical, and the initial complementary investigations nonspecific, making early diagnosis difficult and thus worsening its prognosis. This report describes four infants with herpes encephalitis presenting with an opercular syndrome that left significant sequelae after the acute episode. The opercular syndrome is characterized clinically by a disturbance of voluntary control of the facio-linguo-glosso-pharyngeal muscles, affecting speech and swallowing. Recognition of the opercular syndrome as a form of presentation of herpes encephalitis enables early diagnosis to be made in these patients, with the rapid initiation of treatment with acyclovir, improving the clinical course.
García-Ribes
Ainhoa
A
Pediatric Neurology Unit, Hospital Cruces, Bilbao, Vizcaya, Spain. agarcia.ribes@hcru.osakidetza.net
Martínez-González
María Jesús
MJ
Prats-Viñas
Jose María
JM
D020803:Encephalitis, Herpes Simplex / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008410:Masticatory Muscles; D009069:Movement Disorders / Q000821:virology*; D013577:Syndrome