Humoral immune response after primary rubella virus infection and after vaccination.
We measured rubella virus immunoglobulin G (IgG) and IgM levels, as well as IgG avidity indexes, in serum samples taken before or after 6 months either after infection or after vaccination. The results obtained indicate that humoral immune responses are different after primary infection and after vaccination. This may have important consequences on the serological diagnosis of rubella virus infection.
Vauloup-Fellous
C
C
Service de Microbiologie-Immunologie Biologique, Hôpital Antoine Béclère, and Faculté de Médecine, Université Paris-Sud, Clamart Cedex, France. christelle.vauloup@abc.aphp.fr
Grangeot-Keros
L
L
D000914:Antibodies, Viral / Q000097:blood*; D000917:Antibody Formation / Q000276:immunology*; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D007075:Immunoglobulin M / Q000097:blood; D011247:Pregnancy; D012409:Rubella / Q000097:blood* / Q000276:immunology; D012411:Rubella Vaccine / Q000097:blood / Q000276:immunology*; D012412:Rubella virus / Q000276:immunology*; D013997:Time Factors
D000914:Antibodies, Viral; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D012411:Rubella Vaccine; C040901:rubella antibodies