[Can myelopathies secondary to arterio-venous dural fistulae be aggravated by intravenous corticosteroid therapy?].
Dural fistulas are the most common vascular malformations of the spinal cord. They are of unknown origin but constitute a recognized cause of myelopathy. Aggravation of the clinical manifestations, either spontaneously or after invasive procedures, has been described. We report the case of a patient with a four-month history of myelopathic syndrome involving the lower limbs. Intravenous corticosteroid steroid treatment (1g) given for a suspected inflammatory disorder, induced a dramatic flare-up of the neurological symptoms which were reversible within 48 hours after corticosteroid withdrawal. The causal effect of the steroid treatment is discussed.
Söderlund
M E
ME
Service de Neurologie, Centre Hospitalier Universitaire Henri-Mondor, AP/HP, Université Paris XII, Créteil.
Benisty
S
S
Gaston
A
A
Djindjian
M
M
Cesaro
P
P
Créange
A
A
D000893:Anti-Inflammatory Agents / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use; D020785:Central Nervous System Vascular Malformations / Q000150:complications* / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000601:surgery; D003248:Constipation / Q000209:etiology; D038524:Diffusion Magnetic Resonance Imaging; D006801:Humans; D007262:Infusions, Intravenous; D008297:Male; D008775:Methylprednisolone / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use; D008875:Middle Aged; D020336:Paraparesis, Spastic / Q000209:etiology*; D011859:Radiography; D020886:Somatosensory Disorders / Q000209:etiology*; D016055:Urinary Retention / Q000209:etiology; D014711:Vertebral Artery / Q000000981:diagnostic imaging
D000893:Anti-Inflammatory Agents; D008775:Methylprednisolone