title: ZHARP: three-dimensional motion tracking from a single image plane.
abstract: Three-dimensional imaging and quantification of myocardial function are essential steps in the evaluation of cardiac disease. We propose a tagged magnetic resonance imaging methodology called zHARP that encodes and automatically tracks myocardial displacement in three dimensions. Unlike other motion encoding techniques, zHARP encodes both in-plane and through-plane motion in a single image plane without affecting the acquisition speed. Postprocessing unravels this encoding in order to directly track the 3-D displacement of every point within the image plane throughout an entire image sequence. Experimental results include a phantom validation experiment, which compares zHARP to phase contrast imaging, and an in vivo study of a normal human volunteer. Results demonstrate that the simultaneous extraction of in-plane and through-plane displacements from tagged images is feasible.
authors.affiliation: Department of Electrical and Computer Engineering, Johns Hopkins University, Baltimore, MD 21218, USA. khaled@jhu.edu
authors.forename: Khaled Z
authors.initials: KZ
authors.lastname: Abd-Elmoniem
authors.forename: Matthias
authors.initials: M
authors.lastname: Stuber
authors.forename: Nael F
authors.initials: NF
authors.lastname: Osman
authors.forename: Jerry L
authors.initials: JL
authors.lastname: Prince
mesh_terms: D000328:Adult; D000465:Algorithms; D001185:Artificial Intelligence; D005240:Feasibility Studies; D006321:Heart / Q000033:anatomy & histology* / Q000502:physiology*; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D021621:Imaging, Three-Dimensional / Q000379:methods*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D009038:Motion; D009068:Movement / Q000502:physiology*; D009200:Myocardial Contraction / Q000502:physiology; D010363:Pattern Recognition, Automated / Q000379:methods*; D019047:Phantoms, Imaging; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013382:Subtraction Technique