Acute polyarthritis revealing hepatitis E.
We report a case of acute hepatitis E occurring in a 51-year-old French woman, revealed by an abrupt onset of polyarthritis involving the ankles and knees followed by the wrists and fingers. Polyarthritis lasted up to 3 months without recurrence. Our case was characterised by a 9-month prolonged viraemia with persistence of specific IgM in the serum. The hepatitis E virus belonged to genotype 3 and may have been contracted in France or during travel to hyperendemic areas. Our case shows that acute polyarthritis could be another systemic manifestation of hepatitis E virus infection.
Serratrice
Jacques
J
Service de Médecine Interne, CHU Timone, 264 rue Saint Pierre, 13385, Marseille Cedex 5, France.
Disdier
Patrick
P
Colson
Philippe
P
Ene
Nicoleta
N
de Roux
Christine Serratrice
CS
Weiller
Pierre-Jean
PJ
D000208:Acute Disease; D001168:Arthritis / Q000150:complications* / Q000175:diagnosis*; D005260:Female; D006508:Hepatitis Antibodies / Q000737:chemistry; D016751:Hepatitis E / Q000150:complications* / Q000175:diagnosis*; D016752:Hepatitis E virus / Q000235:genetics; D006801:Humans; D007075:Immunoglobulin M / Q000378:metabolism; D008875:Middle Aged; D012367:RNA, Viral / Q000235:genetics; D016896:Treatment Outcome; D014766:Viremia / Q000175:diagnosis
D006508:Hepatitis Antibodies; D007075:Immunoglobulin M; D012367:RNA, Viral