title: Die Alkaloide von Uncaria tomentosa und ihre Phagozytose-steigernde Wirkung.
abstract: From the roots of UNCARIA TOMENTOSA six oxindol alkaloids have been isolated and identified as isopteropodin, pteropodin, mitraphyllin, isomitraphyllin, rynchophyllin and isorynchophyllin. By ion pair chromatography on HPLC a fingerprint analysis has been worked out which allowed to differentiate between various UNICARIA-species and drug preparations. With the exception of mitraphyllin and rynchophyllin all alkaloids showed a pronounced enhancement effect on phagozytosis, determined in two IN VITRO tests and the IN VIVO-carbon clearance test.
authors.affiliation: Institut für Pharmazeutische Biologie der Universität München, D-8000 München 2, Karlstraße 29.
authors.forename: H
authors.initials: H
authors.lastname: Wagner
authors.forename: B
authors.initials: B
authors.lastname: Kreutzkamp
authors.forename: K
authors.initials: K
authors.lastname: Jurcic