The efficacy of linear polarized polychromatic light on burn wound healing: an experimental study on rats.
We aimed to investigate the questionable effect of linear polarized polychromatic light on burn wound healing in rats. Two deep second-degree burn wounds on the backside of each of 21 Sprague-Dawley rats were created with a standard burning procedure by applying a heated plaque. Burned regions located right dorsolaterally and classified as group I lesions were treated with linear polarized polychromatic light + open dressing + antibacterial pomade, whereas group II lesions were located left dorsolaterally and treated with only open dressing + antibacterial pomade. Macroscopic evaluation was performed for determination of the completed wound closure rate, measurement of burn wound area, and investigation of macroscopic edema, hyperemia, and epithelialization. Histopathological evaluation included monitoring of epithelialization, vascularization, origination of granulation tissue, inflammatory cell response, and total histopathological score on days 7, 14, and 21 after burn creation. Macroscopic evaluation revealed more obvious epithelialization in group I lesions between days 6 and 15. The number of completely closed wounds was higher in group I than in group II on days 16 and 21. The average area of burn wounds was lower from day 5, hyperemia was less on days 2 to 17, and edema was less from day 4 to day 13 in group I lesions. Histopathological evaluation revealed a higher rate of epithelialization on day 7 and higher vascularization occurrence on day 21 in group I lesions. Linear polarized polychromatic light seems to be effective in the treatment of burn wounds and in the promotion of healing. This may be related to linear polarized polychromatic light stimulation of epithelialization and vascularization.
Karadag
Ceyda Akci
CA
Physical Medicine and Rehabilitation Department, Trakya University Medical Faculty, Edirne, Turkey.
Birtane
Murat
M
Aygit
A Cemal
AC
Uzunca
Kaan
K
Doganay
Latife
L
D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D001458:Bandages; D002056:Burns / Q000473:pathology* / Q000628:therapy*; D003131:Combined Modality Therapy; D004487:Edema / Q000628:therapy; D004847:Epithelial Cells / Q000473:pathology; D005260:Female; D006097:Granulation Tissue / Q000473:pathology; D006940:Hyperemia / Q000628:therapy; D007249:Inflammation / Q000628:therapy; D023421:Models, Animal; D010789:Phototherapy / Q000379:methods*; D051381:Rats; D017207:Rats, Sprague-Dawley; D012867:Skin / Q000098:blood supply / Q000473:pathology; D014945:Wound Healing
D000900:Anti-Bacterial Agents