title: [Are there some clinical factors that indicate the best moment of the surgery in the congenital diaphragmatic hernia?].
abstract: OBJECTIVE
  To determine if the needs of cardiopulmonary support of neonates with congenital diaphragmatic hernia (CDH) they can be indicators for the election of the most suitable moment to the surgery.
  
  
  METHODS
  We treated 16 consecutive neonates with congenital diaphragmatic hernia (CDH) from 2004 to 2005. Mean birth weight was 2900.63 +/- 531.51 g. Patients was divided in 2 groups. Group A: newborns without adrenaline nor noradrenaline like vasoactive drugs and conventional respiratory assistant; the surgery was performed during the first 48 hours of life. Group B: newborns with adrenaline or noradrenaline like vasoactive drugs, high-frequency oscillatory ventilation or extracorporeal membrane oxygenation; surgery was delayed (10.66 +/- 8.26 days).
  
  
  RESULTS
  Four neonates died during the first 24 hours of life without surgical treatment not fulfilling criteria of support ECMO. Five patients were operated during the first 48 hours, fulfilling all of them the clinical criteria of the group A. Mortality does not exist in this group. Seven patients were operated late fulfilling the criteria of the group B. They all needed VAFO. Two patients of this group needed support ECMO. The survival rate in this group was 83.3%.
  
  
  CONCLUSIONS
  In our opinion, the patients with CDH that need initially high cardiopulmonary support, VAFO and/or ECMO would be necessary a time of wait to realize the surgery. In those patients who don't need this level of treatment the delay would not justify itself in the surgical intervention.
authors.affiliation: Servicio Cirugía Pediátrica, Hospital Infantil Gregorio Marañón, Madrid. parente80@hotmail.com
authors.forename: A
authors.initials: A
authors.lastname: Parente
authors.forename: A
authors.initials: A
authors.lastname: Cañizo
authors.forename: A
authors.initials: A
authors.lastname: Laín
authors.forename: O
authors.initials: O
authors.lastname: Sánchez
authors.forename: J
authors.initials: J
authors.lastname: Cerdá
authors.forename: E
authors.initials: E
authors.lastname: Molina
authors.forename: M A
authors.initials: MA
authors.lastname: García-Casillas
authors.forename: R
authors.initials: R
authors.lastname: Romero
authors.forename: J A
authors.initials: JA
authors.lastname: Matute
authors.forename: B
authors.initials: B
authors.lastname: Bernardo
authors.forename: M
authors.initials: M
authors.lastname: Sánchez-Luna
authors.forename: J
authors.initials: J
authors.lastname: Vázquez
mesh_terms: D015199:Extracorporeal Membrane Oxygenation; D005260:Female; D006548:Hernia, Diaphragmatic / Q000175:diagnosis / Q000601:surgery*; D006612:High-Frequency Ventilation; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D011379:Prognosis; D012189:Retrospective Studies; D012307:Risk Factors; D016896:Treatment Outcome