[Detection of cytomegalovirus antibody activity in intravenous preparations of immunoglobulins with parallel-line method].
The study demonstrated a possibility to detect specific anti-CMV antibody activity in intravenous preparations of immunoglobulins by qualitative immunoenzyme analysis using parallel-line method. Independently of production technology, specificity, and the activity level, the preparations had a dose-response curve that was parallel to that of a standard sample with five-point linearity at double-step dilution. This makes it possible to use the test system DS-ELISA-ANTI-CMV-G to detect anti-CMV antibody activity in ready-for-use preparations.
Israfilov
A G
AG
Davletbaeva
L R
LR
Magazov
R Sh
RSh
Patrakova
A Z
AZ
Tuĭgunov
M M
MM
D000914:Antibodies, Viral / Q000032:analysis*; D003587:Cytomegalovirus / Q000187:drug effects / Q000276:immunology*; D003586:Cytomegalovirus Infections / Q000188:drug therapy* / Q000821:virology; D004797:Enzyme-Linked Immunosorbent Assay; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000494:pharmacology*; D007155:Immunologic Factors / Q000494:pharmacology*
D000914:Antibodies, Viral; D016756:Immunoglobulins, Intravenous; D007155:Immunologic Factors