title: Allergy to technetium-labelled nanocolloidal albumin for sentinel node identification.
abstract: Optimal sentinel node identification requires using the combination technique with blue dye and radiocolloid. Allergic reactions to the common blue dyes in use are well recognised. In this report, we present a patient with breast carcinoma who developed a type I hypersensitivity reaction to intradermal injection of technetium-99m labelled nanocolloidal albumin. While reactions to colloids are rare, and in this case minor, operators using this radiopharmaceutical should be prepared for a potential severe anaphylactic reaction.
authors.affiliation: Department of Surgery, Royal Free and University College Medical School, University College London, London, UK.
authors.forename: Dennis W
authors.initials: DW
authors.lastname: Chicken
authors.forename: Reza
authors.initials: R
authors.lastname: Mansouri
authors.forename: Peter J
authors.initials: PJ
authors.lastname: Ell
authors.forename: Mohammed R S
authors.initials: MR
authors.lastname: Keshtgar
mesh_terms: D000369:Aged, 80 and over; D001943:Breast Neoplasms / Q000000981:diagnostic imaging; D004396:Coloring Agents / Q000009:adverse effects*; D004342:Drug Hypersensitivity / Q000209:etiology*; D005260:Female; D006801:Humans; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals / Q000009:adverse effects*; D012394:Rosaniline Dyes / Q000009:adverse effects*; D021701:Sentinel Lymph Node Biopsy; D013668:Technetium Tc 99m Aggregated Albumin / Q000009:adverse effects*
chemical_list: D004396:Coloring Agents; D019275:Radiopharmaceuticals; D012394:Rosaniline Dyes; D013668:Technetium Tc 99m Aggregated Albumin; C008769:sulfan blue