[The pharmacological treatment of abulic posttraumatic state in children-preliminary report].
The aim of the study was the evaluation of clinical condition of the children treated by Gliatilin and Dexamin for posttraumatic abulic state.


METHODS
The study included 12 children (8 boys, 4 girls) at the age range between 7-16 years (mean age 7.8 years). The evaluation of clinical condition was performed on admission to the Department, and then at 3rd, 6th and 12th month after head injury. The authors analyzed the kind of injury (posttraumatic changes in neuroimaging) and evolution of patients' clinical condition in the follow-up.


RESULTS
The most commonly observed reasons of trauma were motor vehicle accidents. The kind of pathology found on the base of neuroimaging did not affect the results of treatment. The patients were treated by Gliatilin, Dexamin or both. In spite of this treatment all children were rehabilitated and their hearing, sight and speech organ were stimulated. Six months after injury only one patient still presented abulic state and six of our patients were in good general condition. None of our patients revealed abulic state after 12 months of head trauma. In two children the Dexamin treatment was given up for seizures. We did not observe any side effects of Gliatilin.


CONCLUSIONS
The kind of trauma and posttraumatic intracranial pathology do not determine the prognosis. The evaluation of treatment should be performed after 6-12 months. Gliatilin and Dexamin treatment improves the clinical state of patients with posttraumatic abulic state.
Wojaczyńska-Stanek
Katarzyna
K
Z Kliniki Pediatrii i Neurologii Wieku Rozwojowego Katedry Pediatrii Slaskiej Akademii Medycznej w Katowicach.
Wesołek-Kamińska
Beata
B
Kopyta
Ilona
I
Marszał
Elzbieta
E
D000063:Accidents, Traffic; D000293:Adolescent; D000648:Amnesia, Retrograde / Q000188:drug therapy / Q000534:rehabilitation; D001924:Brain Concussion / Q000188:drug therapy* / Q000534:rehabilitation; D002648:Child; D020207:Coma, Post-Head Injury / Q000188:drug therapy* / Q000534:rehabilitation; D006259:Craniocerebral Trauma; D003913:Dextroamphetamine / Q000008:administration & dosage*; D005260:Female; D015600:Glasgow Coma Scale; D005997:Glycerylphosphorylcholine / Q000008:administration & dosage*; D006801:Humans; D008297:Male; D012720:Severity of Illness Index; D013566:Sympathomimetics / Q000494:pharmacology*; D016896:Treatment Outcome
D013566:Sympathomimetics; D005997:Glycerylphosphorylcholine; D003913:Dextroamphetamine