Chromium-catalyzed arylmagnesiation of alkynes.
[reaction: see text] Arylmagnesiation of unfunctionalized alkynes in the presence of catalytic amounts of chromium(II) chloride and pivalic acid proceeds with high stereoselectivity. The alkenylmagnesium intermediate reacts with various electrophiles to afford the corresponding tetrasubstituted olefins in good yields.
Murakami
Kei
K
Department of Material Chemistry, Graduate School of Engineering, Kyoto University, Kyoto-daigaku Katsura, Nishikyo-ku, Kyoto 615-8510, Japan.
Ohmiya
Hirohisa
H
Yorimitsu
Hideki
H
Oshima
Koichiro
K