Expansion cranioplasty with jackscrew distracters for craniosynostosis and intracranial hypertension in transplanted osteopetrosis.
BACKGROUND
An 11-month-old boy with autosomal recessive infantile osteopetrosis presented, 7 months after bone marrow transplantation, with normal ventricular size and life-threatening intracranial hypertension due to pansynostosis.


METHODS
The cranial vault was expanded by using jackscrew distracters to upwardly advance the upper part of the calvarium.


RESULTS
The procedure achieved a 15-mm upward expansion of the cranial vault over a 15-day period, and the volume of the cranial vault was increased by 139 ml. All clinical manifestations of intracranial hypertension resolved.


CONCLUSIONS
Cranial vault expansion with jackscrew distracters was successful in relieving intracranial hypertension in an infant with pancraniosynostosis complicating bone marrow transplanted malignant infantile osteopetrosis.
Dowlati
Dylaan
D
Department of Neurosurgery, The University of Colorado Health Sciences Center and The Children's Hospital, Denver, USA.
Winston
Ken R
KR
Ketch
Lawrence L
LL
Quinones
Ralph
R
Giller
Roger
R
Frattini
Annalisa
A
van Hove
Johan
J
D002508:Cephalometry; D002869:Chromosome Aberrations; D003398:Craniosynostoses / Q000175:diagnosis / Q000235:genetics / Q000601:surgery*; D004252:DNA Mutational Analysis; D005500:Follow-Up Studies; D005808:Genes, Recessive / Q000235:genetics; D006580:Genetic Carrier Screening; D018380:Hematopoietic Stem Cell Transplantation; D006801:Humans; D007231:Infant, Newborn; D019586:Intracranial Hypertension / Q000175:diagnosis / Q000601:surgery*; D008279:Magnetic Resonance Imaging; D008297:Male; D019857:Osteogenesis, Distraction / Q000295:instrumentation*; D010022:Osteopetrosis / Q000175:diagnosis / Q000235:genetics / Q000628:therapy*; D011183:Postoperative Complications / Q000175:diagnosis / Q000601:surgery*; D012086:Reoperation; D014057:Tomography, X-Ray Computed; D025262:Vacuolar Proton-Translocating ATPases / Q000235:genetics
C472421:TCIRG1 protein, human; D025262:Vacuolar Proton-Translocating ATPases