title: Surgical treatment of 82 patients with diabetic lower limb ischemia by distal arterial bypass.
abstract: BACKGROUND
  Diabetic lower limb ischemia is a serious complication of diabetes mellitus. This study was conducted to investigate the effectiveness of distal arterial bypass treatment in diabetic patients with lower limb ischemia.
  
  
  METHODS
  From July 2000 to July 2004, 96 lower limbs of 82 diabetic patients (type 2) with severe lower limb ischemia were treated in Xuan Wu Hospital. Arterial bypass with femoro-popliteal polytetrafluoroethylene (PTFE) and graft-tibial autologous grafts was performed on 31 limbs (32.3%). Popliteal-tibial artery bypass alone was performed on 22 limbs (22.9%). Combined iliac artery stenting, femoro-popliteal artery PTFE graft bypass, and graft-tibial artery autologous graft bypass was performed on 12 limbs (12.5%), and femoro-tibial artery graft bypass was performed on 10 limbs (10.4%). Popliteal-tibial-pedal artery graft bypass was performed on 7 limbs (7.3%).
  
  
  RESULTS
  Arterial grafts in 92 limbs of 79 patients were patent on discharge. Three patients with 4 ischemic limbs (3.7%) died of respiratory failure 12 hours, 3 days and 7 days after operation respectively. Early operation success rate was 96.3% (79/82). Graft patency rate of patients on discharge was 95.8% (92/96). The short-term total effectiveness rate was 83.3% (80/96). Foot ulcer healing rate was 35.7% (10/28). 97.4% (75/77) patients were followed up for a mean of 13.5 months. The long-term total effective rate was 80.7% (71/88). The total amputation rate was 4.5% (4/88). Mortality was 4.5%. The total graft patency rate was 90.9% (80/88).
  
  
  CONCLUSIONS
  In the treatment of diabetic foot, distal lower limb arterial bypass can help to avoid amputation or lower the amputation level, and may promote foot ulcer healing and improve patient's quality of life.
authors.affiliation: Department of Vascular Surgery, Xuan Wu Hospital, Institute of Vascular Surgery, Capital Medical University, Beijing 100053, China. gu-yq@263.net
authors.forename: Yong-quan
authors.initials: YQ
authors.lastname: Gu
authors.forename: Jian
authors.initials: J
authors.lastname: Zhang
authors.forename: Li-xing
authors.initials: LX
authors.lastname: Qi
authors.forename: Heng-xi
authors.initials: HX
authors.lastname: Yu
authors.forename: Jian-xin
authors.initials: JX
authors.lastname: Li
authors.forename: Xue-feng
authors.initials: XF
authors.lastname: Li
authors.forename: Lian-rui
authors.initials: LR
authors.lastname: Guo
authors.forename: Tao
authors.initials: T
authors.lastname: Luo
authors.forename: Shi-jun
authors.initials: SJ
authors.lastname: Cui
authors.forename: Zhong-gao
authors.initials: ZG
authors.lastname: Wang
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001166:Arteriovenous Shunt, Surgical; D003925:Diabetic Angiopathies / Q000601:surgery*; D005260:Female; D005263:Femoral Artery / Q000601:surgery*; D006801:Humans; D007511:Ischemia / Q000601:surgery*; D035002:Lower Extremity / Q000098:blood supply*; D008297:Male; D008875:Middle Aged; D011138:Polytetrafluoroethylene; D011150:Popliteal Artery / Q000601:surgery*
chemical_list: D011138:Polytetrafluoroethylene