title: Puberty moderates genetic influences on disordered eating.
abstract: BACKGROUND
  Previous research suggests that genetic influences on disordered eating may be greater in pubertal than pre-pubertal girls. Although these findings are consistent with pubertal activation of genetic influences on disordered eating, earlier studies were unable to directly test this hypothesis. The purpose of the present study therefore was to directly examine this possibility by investigating whether pubertal development moderates genetic influences on disordered eating.
  
  
  METHODS
  Participants were 510 female adolescent twins from the Minnesota Twin Family Study. Disordered eating was measured with the Total Score of the Minnesota Eating Behavior Survey, while pubertal status was assessed with the Pubertal Development Scale.
  
  
  RESULTS
  Consistent with our hypothesis, model-fitting indicated significant increases in genetic influence on disordered eating with advancing pubertal development.
  
  
  CONCLUSIONS
  These findings suggest that puberty influences the expression of genes for disordered eating.
authors.affiliation: Department of Psychology, Michigan State University, East Lansing, MI 48824-1116, USA. klump@msu.edu
authors.forename: Kelly L
authors.initials: KL
authors.lastname: Klump
authors.forename: Patrick S
authors.initials: PS
authors.lastname: Perkins
authors.forename: S
authors.initials: S
authors.lastname: Alexandra Burt
authors.forename: Matt
authors.initials: M
authors.lastname: McGue
authors.forename: William G
authors.initials: WG
authors.lastname: Iacono
mesh_terms: D000293:Adolescent; D002648:Child; D005247:Feeding Behavior; D001068:Feeding and Eating Disorders / Q000175:diagnosis / Q000453:epidemiology / Q000235:genetics*; D005260:Female; D015870:Gene Expression; D006801:Humans; D008910:Minnesota / Q000453:epidemiology; D011627:Puberty / Q000502:physiology*; D011795:Surveys and Questionnaires; D014427:Twins / Q000235:genetics / Q000523:psychology