[Hyponatraemic encephalopathy and rhabdomyolysis. Complications after preparation for colonoscopy with mannitol].
In the preparation for colonoscopy, it is necessary to drink a great deal of often hypo-osmotic fluid. Therefore, the electrolytes and intra- and extracellular water are disequilibrated. Most of the patients tolerate this without any subjective or objective symptoms. In our case, a young male patient suffered from a severe hyponatriaemia with encephalopathy for more than 48 h through the preparation for an elective ambulant colonoscopy with mannite. Furthermore, he developed a rhabdomyolysis (either through lying on the floor in coma for more than 9 h, through the hyponatriaemia itself or through compensation of the hyponatriaemia) that lasted for ca. 1 week.
Veitenhansl
M
M
Medizinische Klinik, Klinikum der Universität München, Standort Innenstadt, Ziemssenstrasse 1, 80336 Munich, Germany. Martin.Veitenhansl@med.uni-muenchen.de
Reisch
N
N
Schmauss
S
S
Wörnle
M
M
Gärtner
R
R
D000328:Adult; D001927:Brain Diseases / Q000139:chemically induced* / Q000175:diagnosis; D003113:Colonoscopy / Q000009:adverse effects* / Q000379:methods; D004234:Diuretics, Osmotic / Q000009:adverse effects; D006801:Humans; D007010:Hyponatremia / Q000139:chemically induced* / Q000175:diagnosis; D008297:Male; D008353:Mannitol / Q000009:adverse effects*; D011292:Premedication / Q000009:adverse effects* / Q000379:methods; D012206:Rhabdomyolysis / Q000139:chemically induced* / Q000175:diagnosis
D004234:Diuretics, Osmotic; D008353:Mannitol