title: Biocompatibility of diamond-like nanocomposite thin films.
abstract: Diamond-like nanocomposite (DLN) films consist of network structure of amorphous carbon and quartz like silicon. In the present work, DLN films have been synthesized on pyrex glass and subsequently, their biocompatibility have been investigated through primary and secondary cell adhesion, cytotoxicity, protein adsorption and murine peritoneal macrophage activation experiments. Variable degree of cell and protein response have been found based on variable film synthesis parameters but in overall, required biocompatibility has been established for all types of film-coating.
authors.affiliation: Department of Biotechnology, Indian Institute of Technology, Kharagpur, India.
authors.forename: T
authors.initials: T
authors.lastname: Das
authors.forename: D
authors.initials: D
authors.lastname: Ghosh
authors.forename: T K
authors.initials: TK
authors.lastname: Bhattacharyya
authors.forename: T K
authors.initials: TK
authors.lastname: Maiti
mesh_terms: D000327:Adsorption; D000818:Animals; D001672:Biocompatible Materials / Q000737:chemistry* / Q000633:toxicity; D002244:Carbon / Q000737:chemistry; D002448:Cell Adhesion / Q000187:drug effects; D002460:Cell Line; D018130:Diamond / Q000737:chemistry; D066298:In Vitro Techniques; D008262:Macrophage Activation / Q000187:drug effects; D017737:Macrophages, Peritoneal / Q000166:cytology / Q000187:drug effects; D008422:Materials Testing; D051379:Mice; D053761:Nanocomposites / Q000737:chemistry* / Q000633:toxicity
chemical_list: D001672:Biocompatible Materials; D002244:Carbon; D018130:Diamond