Leishmania (Viannia) braziliensis infection in two Colombian dogs: a note on infectivity for sand flies and response to treatment.
BACKGROUND
Although canine cutaneous leishmaniasis has been reported in several foci of South America, no published information from Colombia is available.


OBJECTIVE
We report on two cases found in the Pacific coast region of this country, which presented as a single scrotal ulcer in one dog, and two ulcers on the external surface of the ear in a second dog.


METHODS
Parasites were isolated by culture in Senekjie's culture medium and identified using monoclonal antibodies. The capacity of these dogs to transmit the parasites to sand fly vectors (Lutzomyia trapidoi, Lutzomyia gomezi, Lutzomyia longipalpis, Lutzomyia youngi) was tested by allowing the flies to feed on the lesion borders.


RESULTS
Both isolates were identified as Leishmania (Viannia) braziliensis. No infections were detected upon dissection of engorged flies. A single peri-and sub-lesional injection of 1-2 ml of pentavalent antimony in the dog with ear lesions resulted in clinical cure 6 weeks post-treatment.


CONCLUSIONS
These observations suggest that although dogs are susceptible to L. braziliensis, their reservoir competence could be low. However, if further studies indicate that canines are capable reservoir hosts of L. Viannia spp., the local treatment of lesions could become a feasible approach to diminish the risk of human infection in the peridomestic setting, without sacrificing infected dogs.
Travi
Bruno L
BL
Centro Internacional de Entrenamiento e Investigaciones Médicas, Cali, Colombia. travib@cideim.org.co
Tabares
Carlos Javier
CJ
Cadena
Horacio
H
D000818:Animals; D000981:Antiprotozoal Agents / Q000627:therapeutic use*; D003105:Colombia; D004283:Dog Diseases / Q000188:drug therapy* / Q000469:parasitology*; D004285:Dogs; D007892:Leishmania braziliensis; D016773:Leishmaniasis, Cutaneous / Q000188:drug therapy* / Q000662:veterinary*; D008536:Meglumine / Q000627:therapeutic use*; D000077485:Meglumine Antimoniate; D009942:Organometallic Compounds / Q000627:therapeutic use*; D011576:Psychodidae / Q000469:parasitology*
D000981:Antiprotozoal Agents; D009942:Organometallic Compounds; D008536:Meglumine; D000077485:Meglumine Antimoniate