Quadrivalvular marantic endocarditis (ME) mimicking acute bacterial endocarditis (ABE).
Marantic endocarditis (ME) is defined by noninfectious valvular vegetations. The most common disorders associated with ME are malignancy with or without hypercoagulable state, intercardiac instrumentation, residual vegetations from previously treated infective endocarditis (IE), renal insufficiency, and burns. Another important cause of ME is systemic lupus erythematosus when accompanied by vegetations, that is, Libman-Sacks endocarditis. ME should be differentiated from IE because they may present with similar clinical features. Both ME and IE may present with fever and a heart murmur with or without embolic phenomenon. Leukocytosis and elevated erythrocyte sedimentation rate suggest the diagnosis of IE. The hallmark of IE is a cardiac vegetation and continuous high-grade bacteremia. After exclusion of the causes of culture negative endocarditis, the absence of bacteremia clearly differentiates ME from IE. We present a case of ME mimicking acute bacterial endocarditis (ABE). The differential diagnostic features of ME versus IE are discussed. To the best of our knowledge, this is the first reported case of quadrivalvular ME with massive vegetations on all cardiac valves, as well as the aorta, atria, and pulmonary artery.
Durie
Nicole M
NM
State University of New York School of Medicine, Stony Brook, New York, USA.
Eisenstein
Lawrence E
LE
Cunha
Burke A
BA
Plummer
Maria Maratta
MM
D000208:Acute Disease; D000368:Aged; D001011:Aorta / Q000473:pathology; D003937:Diagnosis, Differential; D004696:Endocarditis / Q000175:diagnosis; D004697:Endocarditis, Bacterial / Q000175:diagnosis*; D017809:Fatal Outcome; D006325:Heart Atria / Q000473:pathology; D006349:Heart Valve Diseases / Q000175:diagnosis*; D006801:Humans; D008297:Male; D009203:Myocardial Infarction / Q000150:complications; D011651:Pulmonary Artery / Q000473:pathology; D012770:Shock, Cardiogenic / Q000209:etiology