title: [Clinical aspects of mucopolysaccharidosis type II].
abstract: OBJECTIVE
  To review the clinical and diagnostic aspects of mucopolysaccharidosis type II (Hunter syndrome).
  
  
  METHODS
  The different phenotypes are described and the multisystem clinical symptoms are considered, with special emphasis on skeletal deformities and cardiorespiratory and neurological complications.
  
  
  CONCLUSIONS
  Paediatricians and certain specialists (in neurology, ORL, rheumatology and cardiology) must be aware of the need to increase the clinical suspicion of this condition, which can nowadays be treated using enzyme replacement therapy.
authors.affiliation: Hospital de Cruces, 48903 Barakaldo, Espana. psanjurjo@hcru.osakidetza.net
authors.forename: P
authors.initials: P
authors.lastname: Sanjurjo-Crespo
mesh_terms: D006801:Humans; D016532:Mucopolysaccharidosis II / Q000175:diagnosis*