Fluorescein angiographic findings in cases with intermediate uveitis in the inactive phase.
BACKGROUND
To determine fundus fluorescein angiography (FA) findings in cases with intermediate uveitis in the inactive phase.


METHODS
This prospective study included all eligible cases with a diagnosis of intermediate uveitis that were treated at the uvea unit of Trakya University ophthalmology department between January 2002 and January 2004. Study criteria included patients in the inactive phase who had no complaints, no biomicroscopic or ophthalmoscopic inflammatory findings in the anterior and posterior segments, and no period of inflammation that had occurred within the previous 6 months. Cases receiving immunosuppressive treatment were not excluded. FA was performed in all cases, which were evaluated by 2 independent observers.


RESULTS
A total of 21 eyes from 21 cases with intermediate uveitis were included in the study. FAs of the cases were taken approximately 8.8 (SD 5.4) months (range 6-23 months) after the last activation. In these FAs, no pathological findings were identified in 5 eyes (23.8%); optic disc hyperfluorescence was observed in 14 eyes (66.7%); large vein staining was observed in 2 eyes (9.5%); peripheral venous leakage was observed in 6 eyes (28.6%); and cystoid macular edema was observed in 5 eyes (23.8%).


CONCLUSIONS
These findings indicate that retinal vascular inflammatory changes persist in cases with intermediate uveitis even if the clinical manifestations have been treated.
Gürlü
Vuslat Pelitli
VP
Department of Ophthalmology, Trakya University, Edirne, Turkey. gurluvuslat@yahoo.com
Alimgil
Murat Levent
ML
Esgin
Haluk
H
D000293:Adolescent; D000328:Adult; D002199:Capillary Permeability; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008269:Macular Edema / Q000175:diagnosis*; D008297:Male; D008875:Middle Aged; D009898:Optic Disk / Q000098:blood supply; D011446:Prospective Studies; D031300:Retinal Vasculitis / Q000175:diagnosis* / Q000188:drug therapy; D012169:Retinal Vein / Q000473:pathology*; D015867:Uveitis, Intermediate / Q000175:diagnosis* / Q000188:drug therapy
D007166:Immunosuppressive Agents