title: Supervised probabilistic segmentation of pulmonary nodules in CT scans.
abstract: An automatic method for lung nodule segmentation from computed tomography (CT) data is presented that is different from previous work in several respects. Firstly, it is supervised; it learns how to obtain a reliable segmentation from examples in a training phase. Secondly, the method provides a soft, or probabilistic segmentation, thus taking into account the uncertainty inherent in this segmentation task. The method is trained and tested on a public data set of 23 nodules for which soft labelings are available. The new method is shown to outperform a previously published conventional method. By merely changing the training data, non-solid nodules can also be segmented.
authors.affiliation: Image Sciences Institute, University Medical Center Utrecht, The Netherlands. bram@isi.uu.nl
authors.forename: Bram
authors.initials: B
authors.lastname: van Ginneken
mesh_terms: D000465:Algorithms; D001185:Artificial Intelligence; D006801:Humans; D008175:Lung Neoplasms / Q000000981:diagnostic imaging; D010363:Pattern Recognition, Automated / Q000379:methods*; D011856:Radiographic Image Enhancement / Q000379:methods*; D011857:Radiographic Image Interpretation, Computer-Assisted / Q000379:methods*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D003074:Solitary Pulmonary Nodule / Q000000981:diagnostic imaging*; D014057:Tomography, X-Ray Computed / Q000379:methods*