title: Extragastrointestinal stromal tumor presenting as a scrotal mass: an unusual case.
abstract: We describe an unusual case of extragastrointestinal stromal tumor (EGIST) presenting as a scrotal mass. A 71-year-old man presented with a gradually enlarging scrotal mass with a 20-year duration. Physical examination revealed a huge (as large as volleyball), round, nontender mass occupying the whole scrotum, which was resected completely. Clinical and radiological findings did not comply with any other primary site disease. Under histological examination, the tumor showed a spindle cell pattern with low cellularity, absence of necrotic and mitotic features. immunohistochemical analysis revealed the tumor reactive for CD117 and CD34, while negative for smooth muscle actin, desmin and S-100 protein. To our knowledge, this is the first reported case of an EGIST involving the scrotum.
authors.affiliation: Department of Urology, Korea University Hospital, Seoul 136-705, Korea.
authors.forename: Seok-Ho
authors.initials: SH
authors.lastname: Kang
authors.forename: Myung-Joon
authors.initials: MJ
authors.lastname: Kim
authors.forename: Min-Gu
authors.initials: MG
authors.lastname: Park
authors.forename: Hong-Seok
authors.initials: HS
authors.lastname: Park
authors.forename: Du-Geon
authors.initials: DG
authors.lastname: Moon
authors.forename: Deuk-Jae
authors.initials: DJ
authors.lastname: Sung
authors.forename: Hyun-Chul
authors.initials: HC
authors.lastname: Kim
authors.forename: Yang-Seok
authors.initials: YS
authors.lastname: Chae
authors.forename: Jun
authors.initials: J
authors.lastname: Cheon
authors.forename: Je-Jong
authors.initials: JJ
authors.lastname: Kim
mesh_terms: D000368:Aged; D018952:Antigens, CD34 / Q000032:analysis; D046152:Gastrointestinal Stromal Tumors / Q000175:diagnosis; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D019009:Proto-Oncogene Proteins c-kit / Q000032:analysis; D012611:Scrotum / Q000473:pathology*; D018312:Sex Cord-Gonadal Stromal Tumors / Q000737:chemistry / Q000473:pathology*
chemical_list: D018952:Antigens, CD34; D019009:Proto-Oncogene Proteins c-kit