[Distribution and metabolism of testosterone in rats].
Distribution and metabolism of testosterone were studied in male and female rats. While no differences between sexes were observed in the hormone distribution to liver, kidney, spleen, heart, adipose tissue, muscle, brain and adrenal, male liver was found to metabolize testosterone mainly to polar compounds; female liver mainly to A-ring reduced compounds.
Fonzo
D
D
Department of Medical Pathology and Clinical Methodology, University of Turin, Italy.
Lauro
R
R
Dogliotti
L
L
Veglio
V
V
De Martinis
C
C
D000273:Adipose Tissue / Q000378:metabolism; D000311:Adrenal Glands / Q000378:metabolism; D000818:Animals; D001921:Brain / Q000378:metabolism; D005260:Female; D006915:Hydroxytestosterones / Q000032:analysis; D007668:Kidney / Q000378:metabolism / Q000648:ultrastructure; D008099:Liver / Q000378:metabolism / Q000648:ultrastructure; D008297:Male; D018482:Muscle, Skeletal / Q000378:metabolism; D009206:Myocardium / Q000378:metabolism; D009928:Organ Specificity; D051381:Rats / Q000378:metabolism*; D017208:Rats, Wistar; D012727:Sex Characteristics; D013154:Spleen / Q000378:metabolism; D013347:Subcellular Fractions / Q000378:metabolism; D013739:Testosterone / Q000378:metabolism*
D006915:Hydroxytestosterones; D013739:Testosterone