title: Kidney metastasis of resected early gastric carcinoma: report of a case.
abstract: We report a rare case of kidney metastasis of resected early gastric cancer in a 67-year-old man. We performed distal gastrectomy with D2 lymph node dissection for early gastric cancer, which was histologically diagnosed as moderately differentiated adenocarcinoma (T1N0M0, stage IA). Preoperatively, his serum carcinoembryonic antigen (CEA) level was 9.5 ng/ml, and this dropped to 7.0 ng/ml postoperatively. However, 1 year 10 months after the operation, we performed partial kidney resection and the lesion was confirmed to be a metastasis of the gastric cancer. Unfortunately, 5 months later, multiple liver metastasis was found, accompanied by a further increase in the serum CEA level to 2 650.8 ng/ml. This case illustrates the poor prognosis associated with a high preoperative serum CEA level, even if early gastric cancer is resected curatively.
authors.affiliation: Department of Surgical Oncology, Research Institute for Radiation Biology and Medicine, Hiroshima University, 1-2-3 Kasumi, Hiroshima 734-8553, Japan.
authors.forename: Yoshiyuki
authors.initials: Y
authors.lastname: Wada
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Yoshida
authors.forename: Jun
authors.initials: J
authors.lastname: Hihara
authors.forename: Kazuaki
authors.initials: K
authors.lastname: Tanabe
authors.forename: Kei
authors.initials: K
authors.lastname: Ukon
mesh_terms: D000230:Adenocarcinoma / Q000097:blood / Q000556:secondary* / Q000628:therapy; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002272:Carcinoembryonic Antigen / Q000097:blood*; D017809:Fatal Outcome; D005743:Gastrectomy; D006801:Humans; D007680:Kidney Neoplasms / Q000556:secondary* / Q000601:surgery; D008113:Liver Neoplasms / Q000188:drug therapy / Q000556:secondary*; D008197:Lymph Node Excision; D008297:Male; D009392:Nephrectomy; D013274:Stomach Neoplasms / Q000097:blood / Q000473:pathology* / Q000601:surgery
chemical_list: D002272:Carcinoembryonic Antigen