title: [Effect of gamma-interferon on hepatic granuloma formation in mice infected by cysticerci of Taenia saginata asiatica].
abstract: Immunohistochemical streptavidin biotin-peroxidase complex method was used to investigate the effect of gamma-interferon (IFN-gamma) on the hepatic granuloma formation and liver fibrosis in mice infected with Taenia saginata in Duyun area of Guizhou Province. The results reveal contrary relation between the level of IFN-gamma in the liver and the degree of liver fibrosis (p<0.01). The injection of IFN-gamma considerably decreased (p<0.01) the area and size of granuloma (p<0.01).
authors.affiliation: Department of Biochemistry, Qiannan Medical College, Duyun 558003, China.
authors.forename: Pu
authors.initials: P
authors.lastname: Li
authors.forename: Huai-en
authors.initials: HE
authors.lastname: Bao
authors.forename: Ju-quan
authors.initials: JQ
authors.lastname: Rong
authors.forename: Zhen-hua
authors.initials: ZH
authors.lastname: Shen
authors.forename: Rong-min
authors.initials: RM
authors.lastname: Dang
authors.forename: Xiao-fei
authors.initials: XF
authors.lastname: He
authors.forename: Rong
authors.initials: R
authors.lastname: Wu
authors.forename: Shui
authors.initials: S
authors.lastname: Jiang
mesh_terms: D000818:Animals; D003551:Cysticercosis / Q000188:drug therapy* / Q000469:parasitology; D003552:Cysticercus / Q000187:drug effects* / Q000254:growth & development; D005260:Female; D006099:Granuloma / Q000188:drug therapy* / Q000469:parasitology; D007150:Immunohistochemistry; D007371:Interferon-gamma / Q000008:administration & dosage / Q000493:pharmacokinetics / Q000627:therapeutic use*; D008099:Liver / Q000187:drug effects / Q000378:metabolism / Q000469:parasitology; D008109:Liver Diseases, Parasitic / Q000188:drug therapy*; D008297:Male; D051379:Mice; D041202:Taenia saginata / Q000187:drug effects / Q000254:growth & development
chemical_list: D007371:Interferon-gamma