title: Enantio- and diastereo-controlled synthesis of (+)-juvabione employing organocatalytic desymmetrization and photoinduced fragmentation.
abstract: (+)-Juvabione, a natural sesquiterpene exhibiting insect juvenile hormone activity, has been synthesized from sigma-symmetric 4-(2-formyl-ethyl)cyclohexanone by employing organocatalytic asymmetric aldolization and Norrish I-type fragmentation as the key steps.
authors.affiliation: Graduate School of Pharmaceutical Sciences, Tohoku University, Aobayama, Sendai 980-8578, Japan.
authors.forename: Noriaki
authors.initials: N
authors.lastname: Itagaki
authors.forename: Yoshiharu
authors.initials: Y
authors.lastname: Iwabuchi
mesh_terms: D002384:Catalysis; D003510:Cyclohexanes / Q000138:chemical synthesis*; D003512:Cyclohexanones / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D003510:Cyclohexanes; D003512:Cyclohexanones; C414814:juvabione