title: Spin coherence transfer in chemical transformations monitored by remote detection NMR.
abstract: We demonstrate a nuclear magnetic resonance (NMR) experiment using continuous flow in a microfluidic channel for studying the transfer of spin coherence in nonequilibrium chemical processes. We use the principle of remote detection, which involves spatially separated NMR encoding and detection coils. As an example, we provide the map of chemical shift correlations for the amino acid alanine as it transitions from the zwitterionic to the anionic form. The presented method uniquely allows for tracking the migration of encoded spins during the course of any chemical transformation and can provide useful information about reaction mechanisms.
authors.affiliation: Department of Chemistry, University of California, Berkeley and Division of Materials Science, Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Building 11-D64, Berkeley, California 94720, USA. sabieh@berkeley.edu
authors.forename: M Sabieh
authors.initials: MS
authors.lastname: Anwar
authors.forename: Christian
authors.initials: C
authors.lastname: Hilty
authors.forename: Chester
authors.initials: C
authors.lastname: Chu
authors.forename: Louis-S
authors.initials: LS
authors.lastname: Bouchard
authors.forename: Kimberly L
authors.initials: KL
authors.lastname: Pierce
authors.forename: Alexander
authors.initials: A
authors.lastname: Pines