[Dengue: sero-epidemiological survey and virological surveillance in Campinas, São Paulo, Brazil].
The epidemiology of dengue in the municipality of Campinas, São Paulo, Brazil, was studied in 1998 using a randomized sero-epidemiological survey. Epidemiological surveillance data from 1996-2003 were also analyzed, with an emphasis on virological surveillance. 1,260 individuals participated in the survey and had blood samples drawn by finger stick on filter paper. Blood samples were tested by EIA-ICC, an enzyme immunoassay using infected cells as antigen. Dengue antibody prevalence (14.79%) was lower than in other surveys in other States of Brazil, but higher than in two other serological surveys in São Paulo State. Dengue antibody prevalence was far higher than the reported case incidence during the 1996, 1997, and 1998 epidemics. Antibody prevalence and reported case incidence in different health districts were disproportional. The article concludes by recommending further research on the significance of transmission rates during epidemics and more intensive virological surveillance, especially in years with few reported cases.
Lima
Virgília Luna Castor de
VL
Superintendencia de Controle de Endemias, Rua Sao Carlos 546, Campinas, SP 13035-420, Brazil. virgilia@sucen.sp.gov.br
Rangel
Osias
O
Andrade
Valmir Roberto
VR
Silveira
Naoko Yanagizawa Jardim da
NY
Oliveira
Susely Salviano de
SS
Figueiredo
Luiz Tadeu M
LT
D000293:Adolescent; D000328:Adult; D000914:Antibodies, Viral / Q000097:blood*; D001938:Brazil / Q000453:epidemiology; D002648:Child; D002675:Child, Preschool; D003715:Dengue / Q000097:blood / Q000453:epidemiology* / Q000276:immunology / Q000635:transmission; D003716:Dengue Virus / Q000276:immunology* / Q000302:isolation & purification; D018563:Disease Notification; D004196:Disease Outbreaks; D005260:Female; D006801:Humans; D007124:Immunoenzyme Techniques; D007074:Immunoglobulin G / Q000097:blood / Q000276:immunology; D015994:Incidence; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008875:Middle Aged; D011159:Population Surveillance; D015995:Prevalence; D016036:Seroepidemiologic Studies; D014504:Urban Health
D000914:Antibodies, Viral; D007074:Immunoglobulin G