Successful treatment of perianal Bowen's disease with imiquimod.
Although perianal Bowen's disease (BD) is a relatively uncommon malignancy, it is being detected with increasing frequency. It has a strong tendency for local recurrence and treatment remains controversial. The effectiveness of different treatment modalities, ranging from aggressive wide local excision with skin grafting to the application of a topical immune response modifier, remains uncertain. To our knowledge only two cases of perianal BD, successfully treated with imiquimod, have been reported. We wish to present the third case, effectively treated with imiquimod.
van Egmond
Sylvia
S
University of Melbourne Department of Medicine (Dermatology), St. Vincent's Hospital, Fitzroy, Australia.
Hoedemaker
Carlijn
C
Sinclair
Rodney
R
D000634:Aminoquinolines / Q000627:therapeutic use*; D001003:Anal Canal; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D001913:Bowen's Disease / Q000188:drug therapy*; D006801:Humans; D000077271:Imiquimod; D008297:Male; D008875:Middle Aged; D012074:Remission Induction; D012878:Skin Neoplasms / Q000188:drug therapy*
D000634:Aminoquinolines; D000970:Antineoplastic Agents; D000077271:Imiquimod