title: [Prognostic value of routine parameters and laboratory parameters after major trauma. A prospective preclinical-clinical study of air rescue patients].
abstract: In this prospective study, 273 air rescue patients with major blunt trauma were followed throughout their prehospital and clinical management. A blood sample was taken upon arrival and data acquired at three defined time points. With these data, for the first time a prognosis prediction model with prehospital and early clinical routine parameters and routine lab parameters was tested for predictive power. Coagulation test, value of base excess, Glasgow Coma Scale (GCS) value, severity of injury, and age appeared to be relevant parameters. The probability of survival after major blunt trauma decreases with increasing age and severity of injury and decreasing values in GCS, base excess, and coagulation test. These data showed that it is possible with the help of easily accessible routine parameters and routine lab parameters to predict individual survival with a high degree of accuracy of 82%.
authors.affiliation: Institut für Notfallmedizin und Medizinmanagement, Klinikum der Universität München, Schillerstr. 53, 80336, München, Germany. christian.lackner@med.uni-muenchen.de
authors.forename: C K
authors.initials: CK
authors.lastname: Lackner
authors.forename: K
authors.initials: K
authors.lastname: Burghofer
authors.forename: E
authors.initials: E
authors.lastname: Stolpe
authors.forename: T
authors.initials: T
authors.lastname: Schlechtriemen
authors.forename: W E
authors.initials: WE
authors.lastname: Mutschler
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D017732:Air Ambulances / Q000706:statistics & numerical data*; D020000:Decision Support Systems, Clinical; D003955:Diagnostic Tests, Routine / Q000706:statistics & numerical data*; D005260:Female; D005858:Germany / Q000453:epidemiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D017063:Outcome Assessment, Health Care / Q000379:methods* / Q000706:statistics & numerical data; D011379:Prognosis; D018570:Risk Assessment / Q000379:methods*; D012307:Risk Factors; D016019:Survival Analysis; D015996:Survival Rate; D014949:Wounds, Nonpenetrating / Q000175:diagnosis* / Q000453:epidemiology*