Effect of carbonates/phosphates as nucleophilic catalysts in dimethylformamide for efficient cyanosilylation of aldehydes and ketones.
Cyanosilylation of aldehydes and aliphatic ketones can be carried out in dimethylformamide even without the use of any catalyst. In the presence of nucleophilic catalysts such as carbonate and phosphate salts, the reaction rate is significantly enhanced.
Prakash
G K Surya
GK
Loker Hydrocarbon Research Institute and Department of Chemistry, University of Southern California, University Park, Los Angeles, CA 90089-1661, USA.
Vaghoo
Habiba
H
Panja
Chiradeep
C
Surampudi
Vijayalakshmi
V
Kultyshev
Roman
R
Mathew
Thomas
T
Olah
George A
GA
D000447:Aldehydes / Q000737:chemistry*; D002254:Carbonates / Q000737:chemistry*; D002384:Catalysis; D003486:Cyanides / Q000737:chemistry*; D004126:Dimethylformamide / Q000737:chemistry*; D007659:Ketones / Q000737:chemistry*; D008956:Models, Chemical; D010710:Phosphates / Q000737:chemistry*; D011188:Potassium / Q000737:chemistry; D014297:Trimethylsilyl Compounds / Q000737:chemistry*
D000447:Aldehydes; D002254:Carbonates; D003486:Cyanides; D007659:Ketones; D010710:Phosphates; D014297:Trimethylsilyl Compounds; C058010:trimethylsilyl cyanide; D004126:Dimethylformamide; C037593:potassium carbonate; D011188:Potassium