Preliminary investigation of bioactivity of nano biocomposite.
Bioactive biomaterials can form a bone-like apatite layer on their surfaces in the body, which is critical to establishing bone bonding between bioactive materials and living tissue. At present study, the bone-like apatite formation in vitro and vivo on the surface of the nano apatite/polyamide composite was studied, and the bioactive composites implanted into the femora of rabbits were also investigated. The results revealed that the bone-like apatite containing carbonate can form on the surface of the biocomposite both in SBF and dorsal muscle of rabbits, and the composite would form directly combination with the natural bone without fibrous capsule tissue between implant and host bone tissue. All of these indicated that the nano biocomposites have excellent bioactivity and can be used for bone replacement.
Jie
Wei
W
Institute of biomaterials, East China University of Science and Technology, Shanghai, PR China. nic7505@263.net
Hua
Hong
H
Lan
Wu
W
Yi
He
H
Yubao
Li
L
D000818:Animals; D001031:Apatites / Q000737:chemistry; D001672:Biocompatible Materials / Q000737:chemistry; D018786:Bone Substitutes / Q000737:chemistry; D020007:Implants, Experimental; D008422:Materials Testing; D008855:Microscopy, Electron, Scanning; D053761:Nanocomposites / Q000737:chemistry / Q000648:ultrastructure; D009757:Nylons / Q000737:chemistry; D016348:Osseointegration; D011817:Rabbits; D013055:Spectrophotometry, Infrared; D013499:Surface Properties; D014961:X-Ray Diffraction
D001031:Apatites; D001672:Biocompatible Materials; D018786:Bone Substitutes; D009757:Nylons