Do hydronephrosis and extracorporeal shock wave lithotripsy affect carbohydrate antigens?
OBJECTIVE
To investigate carbohydrate antigen (CA 19-9, CA 15-3, and CA 125) levels in the patients who had hydronephrosis with renal stones and in whom Extracorporeal shock wave lithotripsy (ESWL) was performed.


METHODS
This prospective study included 20 people with no known disease for control group and 30 patients who had hydronephrosis with renal stones and in whom ESWL was performed between January 2005 and January 2006. None of patients had urinary infection and malignancy. The blood for carbohydrate antigens was taken pre-ESWL and 30 min after ESWL in both groups. CA 19-9, CA 15-3, and CA 125 in the serum were tested with the electro-immunoassay method on the Roche E-170 apparatus with the original Roche kit.


RESULTS
The CA 19-9 and CA 125 values in the patients group were found to be statistically significant when compared with the control group but the CA 15-3 was not found to be significant. However, CA 19-9, CA 15-3, and CA 125 values of post-ESWL were not statistically significant when compared with pre-ESWL group (P > 0.05).


CONCLUSIONS
The average serum values of CA 125 and CA 19-9 in patients were found to be significantly high. However, serum values of CA 19-9, CA 15-3, and CA 125 were not affected by ESWL.
Akgül
Turgay
T
Second Urology Clinic, Ministry of Health Ankara Training and Research Hospital, Ankara, Turkey. turgayakgul@gmail.com
Nuhoğlu
Bariş
B
Ayyildiz
Ali
A
Balci
Uğur
U
Ayyildiz
Sema Nur
SN
Germiyanoğlu
Cankon
C
D000328:Adult; D000368:Aged; D015295:Antigens, Tumor-Associated, Carbohydrate / Q000097:blood*; D018394:CA-125 Antigen / Q000097:blood; D018395:CA-19-9 Antigen / Q000097:blood; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D006869:Hydronephrosis / Q000097:blood* / Q000150:complications / Q000628:therapy*; D007669:Kidney Calculi / Q000097:blood* / Q000150:complications / Q000628:therapy*; D008096:Lithotripsy; D008297:Male; D008875:Middle Aged; D018396:Mucin-1 / Q000097:blood; D011446:Prospective Studies
D015295:Antigens, Tumor-Associated, Carbohydrate; D018394:CA-125 Antigen; D018395:CA-19-9 Antigen; D018396:Mucin-1