title: Pulmonary hypertension associated with chronic respiratory disease.
abstract: Pulmonary hypertension (PH) has long been recognized as a complication of chronic respiratory disease. Recent studies have highlighted the adverse impact PH has on the clinical course of these conditions and have cast doubt on the role of hypoxia in their pathogenesis. Clinicians should carefully consider the possibility of PH during the diagnostic evaluation of chronic respiratory disorders. The usefulness of pharmacologic therapy directed toward PH remains to be determined.
authors.affiliation: Division of Pulmonary and Critical Care Medicine, Johns Hopkins University, 1830 East Monument Street, 5th Floor, Baltimore, MD 21205, USA. rgirgis@jhmi.edu
authors.forename: Reda E
authors.initials: RE
authors.lastname: Girgis
authors.forename: Stephen C
authors.initials: SC
authors.lastname: Mathai
mesh_terms: D002908:Chronic Disease; D015897:Comorbidity; D006801:Humans; D006976:Hypertension, Pulmonary / Q000175:diagnosis / Q000453:epidemiology* / Q000503:physiopathology; D017563:Lung Diseases, Interstitial / Q000453:epidemiology / Q000503:physiopathology; D020097:Natriuretic Peptide, Brain / Q000097:blood; D010102:Oxygen Inhalation Therapy; D011175:Positive-Pressure Respiration; D029424:Pulmonary Disease, Chronic Obstructive / Q000453:epidemiology; D011669:Pulmonary Wedge Pressure; D012140:Respiratory Tract Diseases / Q000453:epidemiology* / Q000503:physiopathology; D012891:Sleep Apnea Syndromes / Q000453:epidemiology / Q000503:physiopathology
chemical_list: D020097:Natriuretic Peptide, Brain