title: A successful pregnancy outcome using testicular sperm from an infertile male pretreated with HCG.
abstract: A very rare case of successful pregnancy was reported using testicular sperm from a severely infertile man given the treatment of hCG in advance. Prior to treatment, no sperm were present in the ejaculate and testicle. hCG was administrated to the patient for spermatogenesis. After a period of hCG treatment, a few immature sperm were observed in the minced testicular specimen. A successful pregnancy was established by ICSI using the sperm. Treatment by administration of hCG to generate sperm followed by ICSI for the azoospermia patients was effective and practicable.
authors.affiliation: Reproduction Center, Department of Obstetrics, The First Affiliated Hospital, Anhui Medical University, Hefei, China. zzg_100@163.com
authors.forename: Y-X
authors.initials: YX
authors.lastname: Cao
authors.forename: Z-G
authors.initials: ZG
authors.lastname: Zhang
mesh_terms: D000328:Adult; D006063:Chorionic Gonadotropin / Q000627:therapeutic use*; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D007248:Infertility, Male / Q000188:drug therapy*; D008297:Male; D011247:Pregnancy; D011256:Pregnancy Outcome; D013087:Spermatids / Q000187:drug effects / Q000502:physiology; D013094:Spermatozoa / Q000502:physiology*; D013737:Testis / Q000187:drug effects / Q000503:physiopathology
chemical_list: D006063:Chorionic Gonadotropin