MRI versus CT for the detection of coronary artery disease: current state and future promises.
CT and MR are two noninvasive imaging techniques that are capable of detecting different aspects of coronary artery disease (CAD). Both techniques can directly and noninvasively visualize the coronary artery tree, allowing detection of atherosclerotic plaques, coronary stenosis, or occlusion. In addition to direct anatomic visualization, MR also allows assessment of stress-induced ischemia. Both dobutamine stress and dipyridamole or adenosine perfusion MR can be used for this purpose with high sensitivity and specificity. Both MR and multidetector CT can also reveal the functional consequences of CAD, that is, reduced regional and global cardiac function, as well as the presence of myocardial infarction. Finally, there is promise that in the future, both techniques may predict individual risk of unstable CAD by identifying vulnerable plaques that are prone to rupture.
Gerber
Bernhard L
BL
Department of Cardiology, Cliniques Universitaires St. Luc, Université Catholique de Louvain, Avenue Hippocrate 10/2803, B-1200 Brussels, Belgium. bernhard.gerber@clin.ucl.ac.be
D002316:Cardiotonic Agents; D002986:Clinical Trials as Topic; D003324:Coronary Artery Disease / Q000000981:diagnostic imaging* / Q000473:pathology*; D004280:Dobutamine; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008279:Magnetic Resonance Imaging / Q000379:methods / Q000639:trends*; D017202:Myocardial Ischemia / Q000175:diagnosis; D011237:Predictive Value of Tests; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed / Q000379:methods / Q000639:trends*
D002316:Cardiotonic Agents; D004280:Dobutamine