Polarizability of G4-DNA observed by electrostatic force microscopy measurements.
G4-DNA, a quadruple helical motif of stacked guanine tetrads, is stiffer and more resistant to surface forces than double-stranded DNA (dsDNA), yet it enables self-assembly. Therefore, it is more likely to enable charge transport upon deposition on hard supports. We report clear evidence of polarizability of long G4-DNA molecules measured by electrostatic force microscopy, while coadsorbed dsDNA molecules on mica are electrically silent. This is another sign that G4-DNA is potentially better than dsDNA as a conducting molecular wire.
Cohen
Hezy
H
Physical Chemistry Department and Center for Nanoscience and Nanotechnology, The Hebrew University, Jerusalem 91904, Israel.
Sapir
Tomer
T
Borovok
Natalia
N
Molotsky
Tatiana
T
Di Felice
Rosa
R
Kotlyar
Alexander B
AB
Porath
Danny
D
D016880:Anisotropy; D004247:DNA / Q000737:chemistry*; D004553:Electric Conductivity; D054856:G-Quadruplexes; D018625:Microscopy, Atomic Force / Q000379:methods*; D008968:Molecular Conformation; D049329:Nanostructures / Q000737:chemistry*; D055672:Static Electricity
D004247:DNA