[Long-term prognosis value of anemia in a non-selected population with heart failure].
OBJECTIVE
Prevalence of anemia in heart failure is variable. Many studies have established a relation between anemia and prognosis in selected patients with heart failure. We have poor information anout the long-term prognosis in non- selected populations.


METHODS
We analyze the presence of anemia during 2 month in 100 consecutive patients in our hospital with a main diagnosis of heart failure (Cardiology or Internal Medicine departments). We defined anemia according to WHO criteria: hemoglobin level lower than 130 g/l (men) and 120 g/l (women). We studied the influence of anemia in long-term prognosis (follow-up of 25+/-18 m).


RESULTS
Mean age was 71.8 (9) years. 41% of patients had anemia. Values of hemoglobin were related to age and creatinine, but not with cardiovascular risk factors. Patients who died (38%) had lower hemoglobin than patients who survived (121 [22] gr/dl vs 130 [17] gr/dl; p<0.02). Mortality in the anemia group was 52.5% vs 32.1% (p<0.04). In the Cox multivariable analisis, anemia was a predictor factor of mortality in the follow-up (RR = 1,55; CI 95%, 1.05-2.47; p<0.04) and functional class (III/IV) (RR=2.52; CI 95%, 1.56-4.07; p<0.001).


CONCLUSIONS
In a non-selected population of patients with heart failure, the prevalence of anemia is high and has independiente prognostic value in long-term mortality with functional advanced class.
Domínguez Franco
Antonio
A
Servicio de Cardiología, Hospital Clínico Universitario Virgen de la Victoria, Málaga, España. antoniodominguez@secardiologia.es
Peña Hernández
José
J
Pérez Caravante
Margarita
M
Muñoz García
Antonio
A
Jiménez Navarro
Manuel
M
De Teresa Galván
Eduardo
E
D000368:Aged; D000369:Aged, 80 and over; D000740:Anemia / Q000453:epidemiology* / Q000209:etiology; D015897:Comorbidity; D003404:Creatinine / Q000097:blood; D005260:Female; D006333:Heart Failure / Q000097:blood* / Q000150:complications; D006454:Hemoglobins / Q000032:analysis; D006801:Humans; D007676:Kidney Failure, Chronic / Q000097:blood / Q000150:complications; D008297:Male; D008875:Middle Aged; D016017:Odds Ratio; D011379:Prognosis; D016016:Proportional Hazards Models; D011446:Prospective Studies; D012307:Risk Factors; D013030:Spain / Q000453:epidemiology; D016019:Survival Analysis
D006454:Hemoglobins; D003404:Creatinine