Out of Africa: what can we learn from HIV-2 about protective immunity to HIV-1?
Most people infected with human immunodeficiency virus 2 (HIV-2) do not progress to disease, even though the minority who do cannot be distinguished clinically from HIV-1-infected patients. Here we review what is known about the basis of viral control in HIV-2 infection.
Rowland-Jones
Sarah L
SL
Medical Research Council Laboratories, Fajara, the Gambia, West Africa. srowland-jones@mrc.gm
Whittle
Hilton C
HC
D000818:Animals; D016665:Cercocebus atys; D018450:Disease Progression; D006169:Guinea-Bissau; D015658:HIV Infections / Q000276:immunology* / Q000821:virology; D015497:HIV-1 / Q000276:immunology*; D015498:HIV-2 / Q000276:immunology*; D006801:Humans; D016097:Simian Acquired Immunodeficiency Syndrome / Q000276:immunology / Q000821:virology; D015302:Simian Immunodeficiency Virus / Q000276:immunology