title: Low-dose oral tri-iodothyronine does not directly increase food intake in man.
abstract: Previously, we have shown that low-dose tri-iodothyronine (T3) increases food intake in rodents. This randomised, double-blind, placebo-controlled study aimed to investigate the effects of low-dose T3 on food intake in normal body weight individuals. However, despite an elevation in fT3 comparable to our earlier studies, administration of low-dose T3 in the fasted state did not stimulate food intake in man.
authors: Department of Metabolic Medicine, Hammersmith Hospital, Imperial College London, London, UK.
authors: N M
authors: NM
authors: Martin
authors: C J
authors: CJ
authors: Small
authors: J L
authors: JL
authors: Lee
authors: S
authors: S
authors: Ellis
authors: W S
authors: WS
authors: Dhillo
authors: K L
authors: KL
authors: Smith
authors: W M
authors: WM
authors: Kong
authors: G S
authors: GS
authors: Frost
authors: S R
authors: SR
authors: Bloom
mesh_terms: D000284:Administration, Oral; D000328:Adult; D018592:Cross-Over Studies; D004311:Double-Blind Method; D004435:Eating / Q000187:drug effects* / Q000502:physiology; D002149:Energy Intake / Q000502:physiology; D004734:Energy Metabolism / Q000502:physiology; D006801:Humans; D008297:Male; D013972:Thyrotropin / Q000097:blood; D014284:Triiodothyronine / Q000008:administration & dosage* / Q000097:blood
chemical_list: D014284:Triiodothyronine; D013972:Thyrotropin