title: Paroxysmal sneezing at the onset of lateral medullary syndrome: cause or consequence?
abstract: Sneezing is known to precede lateral medullary syndrome (LMS). It is usually interpreted as the precipitating cause for a vertebral artery dissection that subsequently causes LMS. Through two case reports and a literature review, we aim to challenge the concept that sneezing at the onset of LMS implies that a dissection is the underlying cause. An 82-year-old man and a 54-year-old man both reported unprovoked explosive pathological sneezing at the onset of the LMS without any delay between sneezing and the other LMS symptoms. Both denied neck trauma or neck pain. There was no conclusive evidence for vertebral artery dissection in either case. Paroxysmal sneezing can be an initial manifestation of lateral medullary ischemia and may not necessarily indicate an underlying vertebral artery dissection as the cause.
authors: Division of Cerebrovascular Diseases, Department of Neurology, Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA.
authors: A J
authors: AJ
authors: Swenson
authors: E C
authors: EC
authors: Leira
mesh_terms: D000369:Aged, 80 and over; D006801:Humans; D014854:Lateral Medullary Syndrome / Q000150:complications* / Q000473:pathology*; D018810:Magnetic Resonance Angiography; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D012912:Sneezing; D014057:Tomography, X-Ray Computed