Distributed cortical networks for focused auditory attention and distraction.
We used behavioral measures and functional magnetic resonance imaging (fMRI) to study the effects of parametrically varied task-irrelevant pitch changes in attended sounds on loudness-discrimination performance and brain activity in cortical surface maps. Ten subjects discriminated tone loudness in sequences that also included infrequent task-irrelevant pitch changes. Consistent with results of previous studies, the task-irrelevant pitch changes impaired performance in the loudness discrimination task. Auditory stimulation, attention-enhanced processing of sounds and motor responding during the loudness discrimination task activated supratemporal (auditory cortex) and inferior parietal areas bilaterally and left-hemisphere (contralateral to the hand used for responding) motor areas. Large pitch changes were associated with right hemisphere supratemporal activations as well as widespread bilateral activations in the frontal lobe and along the intraparietal sulcus. Loudness discrimination and distracting pitch changes activated common areas in the right supratemporal gyrus, left medial frontal cortex, left precentral gyrus, and left inferior parietal cortex.
Rinne
Teemu
T
Department of Psychology, University of Helsinki, and Helsinki Medical Imaging Center, Helsinki University Central Hospital, Finland. teemu.rinne@helsinki.fi
Kirjavainen
Siiri
S
Salonen
Oili
O
Degerman
Alexander
A
Kang
Xiaojian
X
Woods
David L
DL
Alho
Kimmo
K
D000161:Acoustic Stimulation / Q000379:methods; D000328:Adult; D001288:Attention / Q000502:physiology*; D001303:Auditory Cortex / Q000098:blood supply / Q000502:physiology*; D001306:Auditory Pathways / Q000098:blood supply / Q000502:physiology*; D001931:Brain Mapping; D004292:Dominance, Cerebral / Q000502:physiology; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D011930:Reaction Time / Q000502:physiology; D013017:Sound Localization / Q000502:physiology*