[Measurement of fraction of exhaled nitric oxide with the portable NIOX-MINO monitor in healthy adults].
Measurement of the fraction of exhaled nitric oxide (FENO) provides a noninvasive way to monitor asthma treatment in clinical practice. The aim of this study was to determine FENO reference values for measurements recorded with the portable NIOX MINO monitor in a group of healthy volunteers. We also assessed the association between values recorded by the portable monitor and the N-6008 chemiluminescence analyzer used in our pulmonary function laboratory. The FENO values obtained with the portable monitor were consistently higher than those recorded by the N-6008 analyzer; the cutoff value for the portable monitor was 34 ppb (mean + 2 SD). We detected a direct correlation (r=0.92) between the FENO measurements recorded by the 2 monitors (P=.001). The following equation expresses the relationship between measurements from the 2 devices: FENO(NIOX MINO) = 10 + [1.5 FENO(N-6008)]. We did not observe statistically significant correlations between FENO measurements and age, sex, body mass index, or spirometry.
Fortuna
Ana María
AM
Unidad de Función Pulmonar, Departamento de Neumología, Hospital de la Santa Creu i Sant Pau, Facultad de Medicina, Universidad Autónoma de Barcelona, Barcelona, España.
Feixas
Teresa
T
Casan
Pere
P
D000328:Adult; D000367:Age Factors; D015992:Body Mass Index; D001944:Breath Tests / Q000295:instrumentation*; D018592:Cross-Over Studies; D005260:Female; D005541:Forced Expiratory Volume; D006801:Humans; D008163:Luminescent Measurements; D008297:Male; D008875:Middle Aged; D009569:Nitric Oxide / Q000032:analysis*; D012016:Reference Values; D015203:Reproducibility of Results; D012737:Sex Factors; D014797:Vital Capacity
D009569:Nitric Oxide