title: Asymmetric synthesis of 2H-azirine 3-carboxylates.
abstract: [reaction: see text] Dehydrochlorination of methyl 2-chloroaziridine 2-carboxylates generates the first examples of enantiopure 2-substituted 2H-azirine 3-carboxylates which undergo the aza Diels-Alder reaction with dienes to give bicyclic and tricyclic aziridines in good yields.
authors: Department of Chemistry, Temple University, Philadelphia, Pennsylvania 19122, USA. fdavis@temple.edu
authors: Franklin A
authors: FA
authors: Davis
authors: Jianghe
authors: J
authors: Deng
mesh_terms: D001389:Azirines / Q000737:chemistry*; D002264:Carboxylic Acids / Q000138:chemical synthesis / Q000737:chemistry*; D015394:Molecular Structure; D013237:Stereoisomerism
chemical_list: D001389:Azirines; D002264:Carboxylic Acids