Preliminary descriptive statistics of the Taiwanese Registry of Epilepsy and Pregnancy for the first 2 years.
OBJECTIVE
To present the descriptive statistics of the Taiwanese Registry of Epilepsy and Pregnancy (TREP) for the first 2 years.


METHODS
The pregnancies were recruited from May 2004 to January 2006 with a data format compatible with the International Registry of Antiepileptic Drugs and Pregnancy (EURAP) by referral. The data were collected from either face-to-face interview, telephone interview, or chart review by a research nurse. Five questionnaires (A-E) were required for each pregnancy. The preliminary data for the first 2 years are presented with general descriptive statistics.


RESULTS
Until January 2006, 43 pregnancies have been registered. Questionnaire A was completed in 43 cases, questionnaire B completed in 40 cases, questionnaire C completed in 34 cases, questionnaire D completed in 27 cases, and questionnaire E in eight cases. Among the 39 pregnancies known to take antiepileptic drugs (AEDs) during pregnancy, 28 pregnancies took one AED, nine pregnancies took two AEDs, and two pregnancies took three AEDs. The most commonly used drug was carbamazepine (19/39, 48.72%). Among the 27 pregnancies, who had delivered, the cesarean section rate was 44.44% (12/27), the premature birth rate was 7.41% (2/27), and the fetal malformation rate was 3.7% (1/27).


CONCLUSIONS
The preliminary data concluded the efforts of TREP for the first 2 years. Although it is still premature to project a trend out of current data, the registry is expected to provide critical information to local prenatal counseling and contribute further to the international EURAP database.
Chang
Tung-Yao
TY
Department of Obstetrics and Gynecology, Mackay Memorial Hospital, Taipei, Taiwan. mmhchangty-medicine@yahoo.com
Lai
Chi-Wan
CW
Yu
Hsiang-Yu
HY
Hsu
Jenn-Jeih
JJ
Shih
Yang-Hsin
YH
Chen
Chih-Ping
CP
D000328:Adult; D000927:Anticonvulsants / Q000627:therapeutic use; D001724:Birth Weight; D000013:Congenital Abnormalities / Q000453:epidemiology; D036861:Delivery, Obstetric / Q000706:statistics & numerical data; D004363:Drug Utilization / Q000706:statistics & numerical data; D004827:Epilepsy / Q000188:drug therapy / Q000453:epidemiology*; D005260:Female; D006801:Humans; D010298:Parity; D011247:Pregnancy; D011248:Pregnancy Complications / Q000188:drug therapy / Q000453:epidemiology*; D011256:Pregnancy Outcome; D012042:Registries; D013624:Taiwan / Q000453:epidemiology
D000927:Anticonvulsants