title: Large cell neuroendocrine carcinoma of the uterine cervix associated with adenocarcinoma.
abstract: OBJECTIVE
  Large cell neuroendocrine carcinoma (LCNEC) is a rare and aggressive cervical neoplasm. In the present study, we present a 45-year-old woman with large cell neuroendocrine uterine cervical carcinoma with coexisting adenocarcinoma.
  
  
  METHODS
  A 45-year-old G2 P0 presented with vaginal bleeding for 7 months. On pelvic examination, a polypoid mass of the cervix was discovered. Biopsy of the lesion revealed large cell neuroendocrine carcinoma of the cervix. The patient underwent a radical hysterectomy, and then received concurrent chemotherapy and radiation therapy. She has remained disease free until the time of this writing.
  
  
  CONCLUSIONS
  Patients with LCNEC of the cervix have had poor prognoses; hence aggressive multimodality treatment is recommended.
authors: Department of Obstetrics and Gynecology, Cathay General Hospital, Taipei, Taiwan.
authors: Ma-Lee
authors: ML
authors: Ko
authors: Cherng-Jye
authors: CJ
authors: Jeng
authors: Shih-Hung
authors: SH
authors: Huang
authors: Jenta
authors: J
authors: Shen
authors: Su-Chee
authors: SC
authors: Chen
authors: Chii-Ruey
authors: CR
authors: Tzeng
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis* / Q000628:therapy; D018278:Carcinoma, Neuroendocrine / Q000175:diagnosis* / Q000628:therapy; D002584:Cervix Uteri / Q000473:pathology; D005260:Female; D006801:Humans; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000175:diagnosis* / Q000628:therapy; D016896:Treatment Outcome; D002583:Uterine Cervical Neoplasms / Q000175:diagnosis* / Q000628:therapy