Carbohydrate microarrays for assaying galactosyltransferase activity.
[reaction: see text] Carbohydrate microarrays have been used recently for the rapid analysis of glycan-protein or glycan-cell interactions and for the detection of pathogens. As a demonstration of its significance and versatility, the microarray technology has been applied in this effort to assay glycosyltransferase activities. In addition, carbohydrate microarray based methods have been employed to quantitatively determine binding affinities between lectins and carbohydrates.
Park
Sungjin
S
Department of Chemistry, Yonsei University, Seoul 120-749, Korea.
Shin
Injae
I
D050260:Carbohydrate Metabolism; D002241:Carbohydrates / Q000737:chemistry; D005700:Galactosyltransferases / Q000032:analysis* / Q000378:metabolism*; D046228:Microarray Analysis / Q000379:methods*; D015394:Molecular Structure; D013379:Substrate Specificity
D002241:Carbohydrates; D005700:Galactosyltransferases