Conformational changes of coat proteins during vesicle formation.
In coated vesicle formation, coat protein recruitment needs to be spatially and temporally controlled. The coating process involves conformational changes of the coat protein complexes that activate them for interaction with cargo or machinery components and coat polymerization. Here we discuss mechanisms that have emerged recently from studies of the clathrin adaptor and the COPI systems.
Langer
Julian D
JD
Biochemie Zentrum der Universität Heidelberg, Im Neuenheimer Feld 328, 3. OG, # 309, 69120 Heidelberg, Germany.
Stoops
Emily H
EH
Béthune
Julien
J
Wieland
Felix T
FT
D000818:Animals; D036022:Capsid Proteins / Q000737:chemistry*; D018699:Coated Vesicles / Q000737:chemistry / Q000378:metabolism; D008024:Ligands; D010766:Phosphorylation; D011487:Protein Conformation
D036022:Capsid Proteins; D008024:Ligands