A new tricyclic-alpha,beta-unsaturate ketone and a new delta-hexano lactone glycoside from Adenocaulon himalaicum.
Two new compounds, a tricyclic-alpha,beta-unsaturate ketone (adenocaulone) (1) and a delta-hexanolactone glycoside (adenocaulolide) (2), along with 10 known compounds 3-12 were isolated from Adenocaulon himalaicum Edgew. Their structures were elucidated by spectroscopic methods (IR, MS, 1H, 13C and 2D NMR). In addition, the antibacterial activity of compounds 2, 3 and 4 were tested.
Wang
Xiaoxiong
X
State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou, PR China.
Zhang
Qi
Q
Jia
Zhongjian
Z
D015107:4-Butyrolactone / Q000031:analogs & derivatives* / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000494:pharmacology; D019659:Asteraceae / Q000737:chemistry*; D001412:Bacillus subtilis / Q000187:drug effects; D004926:Escherichia coli / Q000187:drug effects; D006027:Glycosides / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D007659:Ketones / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D007783:Lactones / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D010936:Plant Extracts / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D011083:Polycyclic Compounds / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D016339:Spectrometry, Mass, Fast Atom Bombardment; D013211:Staphylococcus aureus / Q000187:drug effects
D000900:Anti-Bacterial Agents; D006027:Glycosides; D007659:Ketones; D007783:Lactones; D010936:Plant Extracts; D011083:Polycyclic Compounds; C520437:adenocaulolide; C520436:adenocaulone; D015107:4-Butyrolactone