title: Progress of study on the relationship between mediators of inflammation and apoptosis in acute pancreatitis.
abstract: As an important pathological feature of acute pancreatitis, apoptosis may occur in multiple organs and relate directly to the progression of disease. It is mainly controlled by the apoptosis gene and also influenced by inflammatory mediators. We summarize here the roles of the main inflammatory mediators (e.g., NO, TNF-alpha, TGF-beta1, IL-10, NF-kappaB) during the pathologic process of acute pancreatitis.
authors: Department of General Surgery, Hangzhou First People's Hospital, Hangzhou, 310006, Zhejiang Province, China. zxp99688@vip.163.com
authors: Xi-Ping
authors: XP
authors: Zhang
authors: Qian
authors: Q
authors: Lin
authors: Yi-Feng
authors: YF
authors: Zhou
mesh_terms: D000208:Acute Disease; D000818:Animals; D017209:Apoptosis; D006801:Humans; D018836:Inflammation Mediators / Q000378:metabolism*; D016753:Interleukin-10 / Q000378:metabolism; D016328:NF-kappa B / Q000378:metabolism; D009569:Nitric Oxide / Q000378:metabolism; D010195:Pancreatitis / Q000378:metabolism* / Q000473:pathology; D053773:Transforming Growth Factor beta1 / Q000378:metabolism; D014409:Tumor Necrosis Factor-alpha / Q000378:metabolism
chemical_list: D018836:Inflammation Mediators; D016328:NF-kappa B; D053773:Transforming Growth Factor beta1; D014409:Tumor Necrosis Factor-alpha; D016753:Interleukin-10; D009569:Nitric Oxide