Peptidoglycan detection by mammals and flies.
Peptidoglycan is an essential component of bacteria. The host exploits the peptidoglycan particular composition and uniqueness to bacteria for specific bacterial recognition. Insects and mammals accomplish this via receptors such as PGRP and Nod proteins.
Chaput
Catherine
C
Department of Cellular Microbiology, Max-Planck Institute, Charitéplatz 1, D-10117 Berlin, Germany. chaput@mpiib-berlin.mpg.de
Boneca
Ivo G
IG
D000818:Animals; D016207:Cytokines / Q000502:physiology; D004331:Drosophila melanogaster / Q000276:immunology; D007113:Immunity, Innate; D047908:Intracellular Signaling Peptides and Proteins / Q000502:physiology; D008322:Mammals / Q000276:immunology; D053473:Nod2 Signaling Adaptor Protein / Q000502:physiology*; D010457:Peptidoglycan / Q000276:immunology*
D016207:Cytokines; D047908:Intracellular Signaling Peptides and Proteins; D053473:Nod2 Signaling Adaptor Protein; D010457:Peptidoglycan; C491877:Pglyrp1 protein, rat