Molecular markers of miscellaneous primary and metastatic tumors of the uterine cervix.
Miscellaneous primary tumors of the uterine cervix are rare. Markers which can be utilized to detect these tumors are very few and in most cases, have not been clinically validated. The information provided in this article will help in developing strategies to discover novel markers and initiate translational research in this ignored area. Based on the reported studies, cytokeratin markers are common in many tumors and few of these rare cancers demonstrate human papilloma-virus (HPV) and Epstein Bar virus (EBV) infection. Due to the very low prevalence of these tumors, epidemiological studies have not been conducted and the etiology of these tumors is largely unknown.
Chauhan
S C
SC
Cancer Biology Research Institute, South Dakota Health Research Foundation and Department of Obstetrics and Gynecology, USA.
Kumar
D
D
Bell
M C
MC
Koch
M D
MD
Verma
M
M
D014408:Biomarkers, Tumor / Q000378:metabolism*; D002277:Carcinoma / Q000175:diagnosis / Q000378:metabolism / Q000556:secondary*; D002471:Cell Transformation, Neoplastic / Q000378:metabolism; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D007633:Keratins / Q000378:metabolism*; D008067:Lipoma / Q000175:diagnosis / Q000378:metabolism; D008545:Melanoma / Q000175:diagnosis / Q000378:metabolism / Q000556:secondary*; D009442:Neurilemmoma / Q000175:diagnosis / Q000378:metabolism / Q000556:secondary; D035583:Rare Diseases / Q000175:diagnosis / Q000378:metabolism / Q000473:pathology; D012509:Sarcoma / Q000175:diagnosis / Q000378:metabolism / Q000556:secondary*; D002583:Uterine Cervical Neoplasms / Q000175:diagnosis* / Q000378:metabolism
D014408:Biomarkers, Tumor; D007633:Keratins