title: Two years follow-up study of the pain-relieving effect of gold bead implantation in dogs with hip-joint arthritis.
abstract: Seventy-eight dogs with pain from hip dysplasia participated in a six-month placebo-controlled, double-blinded clinical trial of gold bead implantation. In the present, non-blinded study, 73 of these dogs were followed for an additional 18 months to evaluate the long-term pain-relieving effect of gold bead implantation. The recently-published results of the six month period revealed that 30 of the 36 dogs (83%) in the gold implantation group showed significant improvement (p = 0.02), included improved mobility and reduction in the signs of pain, compared to the placebo group (60% improvement). In the long-term two-year follow-up study, 66 of the 73 dogs had gold implantation and seven dogs continued as a control group. The 32 dogs in the original placebo group had gold beads implanted and were followed for a further 18 months. A certified veterinary acupuncturist used the same procedure to insert the gold beads as in the blinded study, and the owners completed the same type of detailed questionnaires. As in the blinded study, one investigator was responsible for all the assessments of each dog. The present study revealed that the pain-relieving effect of gold bead implantation observed in the blinded study continued throughout the two-year follow-up period.
authors: Department of Companion Animal Clinical Sciences, Norwegian School of Veterinary Science, Oslo, Norway. gry.jaeger@veths.no
authors: Gry T
authors: GT
authors: Jaeger
authors: Stig
authors: S
authors: Larsen
authors: Nils
authors: N
authors: Søli
authors: Lars
authors: L
authors: Moe
mesh_terms: D000818:Animals; D001168:Arthritis / Q000209:etiology / Q000628:therapy / Q000662:veterinary*; D004283:Dog Diseases / Q000209:etiology / Q000628:therapy*; D004285:Dogs; D004311:Double-Blind Method; D005260:Female; D005500:Follow-Up Studies; D006046:Gold / Q000008:administration & dosage*; D006619:Hip Dysplasia, Canine / Q000150:complications / Q000628:therapy; D006621:Hip Joint; D007794:Lameness, Animal / Q000209:etiology / Q000628:therapy; D008297:Male; D008863:Microspheres; D010146:Pain / Q000209:etiology / Q000662:veterinary*; D059408:Pain Management; D010147:Pain Measurement / Q000662:veterinary; D010166:Palliative Care / Q000379:methods; D011788:Quality of Life; D013997:Time Factors
chemical_list: D006046:Gold