Utilization of recombinant activated factor VII in a case of spontaneous massive haemothorax in a patient with Von Recklinghausen's disease.
Spontaneous haemothorax is a rare and often lethal complication of neurofibromatosis. Two kinds of vascular involvement are described: 1) stenotic or aneurysmatic modifications of large intrathoracic vessels, mainly treated with endovascular techniques; 2) dysplastic alterations in highly vascularized mesenchymal tumors. We describe a rare case of massive intrathoracic haemorrhage due to an upper mediastinic neurofibroma, successfully controlled with recombinant activated factor VII associated with surgical treatment.
Radeschi
G
G
Anesthesia and Intensive Care Unit, San Luigi Hospital, Orbassano (Turin), Italy. g.radeschi@sanluigi.piemonte.it
Boris
E F
EF
Sega
P
P
Odetto
L
L
Venturino
S
S
D000328:Adult; D005167:Factor VII / Q000627:therapeutic use*; D005260:Female; D006491:Hemothorax / Q000188:drug therapy* / Q000209:etiology; D006801:Humans; D009456:Neurofibromatosis 1 / Q000150:complications*; D011994:Recombinant Proteins / Q000627:therapeutic use; D014057:Tomography, X-Ray Computed
D011994:Recombinant Proteins; D005167:Factor VII