Suppressive effect of resistant maltodextrin on postprandial blood triacylglycerol elevation.
BACKGROUND
As the physiological functions of soluble dietary fibre, the favourable efficacy, such as attenuating the absorption of saccharides or lipids, is expected. Resistant maltodextrin, a soluble dietary fibre, was investigated and found that it delays the glucose absorption and attenuates the postprandial rise in the blood glucose levels, however, the efficacy of resistant maltodextrin on lipid metabolism is not yet reported.


OBJECTIVE
We conducted an animal experiment and a human experiment to investigate the effect of resistant maltodextrin on postprandial blood triacylglycerol elevation.


METHODS
1. Rats were fed corn oil with or without resistant maltodextrin and the postprandial changes in triacylglycerol were examined. 2. We then conducted a dietary loading experiment on 13 healthy adult male and female subjects using a meal containing approximately 50 g fat. A beverage not containing resistant maltodextrin was used as a placebo; subjects consumed the loading meal and a beverage containing either 5 g or 10 g resistant maltodextrin; blood was periodically collected to see the changes in serum constituents.


RESULTS
1. The corn oil administration experiment using rats showed that resistant maltodextrin dose-dependently suppressed elevation of blood triacylglycerol levels after corn oil administration. 2. The dietary loading experiment on 13 healthy subjects with 5 or 10 g of resistant maltodextrin showed that; in each administration group, resistant maltodextrin significantly suppressed postprandial elevation of blood triacylglycerol, RLP-cholesterol and insulin.


CONCLUSIONS
These results indicate that resistant maltodextrin ingested with fatty meals suppresses the postprandial elevation of blood triacylglycerol levels.
Kishimoto
Yuka
Y
Research Laboratory, Matsutani Chemical Industry Co., Ltd., 5-3 Kita-Itami, Itami City, Hyogo 664-8508, Japan. yuka-kishimoto@matsutani.co.jp
Oga
Hiroshi
H
Tagami
Hiroyuki
H
Okuma
Kazuhiro
K
Gordon
Dennis T
DT
D000328:Adult; D000818:Animals; D019540:Area Under Curve; D002784:Cholesterol / Q000097:blood*; D003314:Corn Oil; D018592:Cross-Over Studies; D004043:Dietary Fiber / Q000494:pharmacology*; D004305:Dose-Response Relationship, Drug; D005260:Female; D006801:Humans; D007328:Insulin / Q000097:blood*; D008074:Lipoproteins / Q000097:blood*; D008297:Male; D011134:Polysaccharides / Q000494:pharmacology*; D019518:Postprandial Period; D051381:Rats; D017207:Rats, Sprague-Dawley; D016037:Single-Blind Method; D014280:Triglycerides / Q000097:blood*
D004043:Dietary Fiber; D007328:Insulin; D008074:Lipoproteins; D011134:Polysaccharides; D014280:Triglycerides; C112017:remnant-like particle cholesterol; C008315:maltodextrin; D003314:Corn Oil; D002784:Cholesterol