title: Quality of life after multiple trauma: the effect of early onset psychotherapy on quality of life in trauma patients.
abstract: OBJECTIVE
  The aim of this study was to improve health-related quality of life (HRQOL) related to depression, anxiety, pain, physical functioning and social aspects for severely injured trauma survivors by early onset cognitive behavioural therapy applied on the surgical ward.
  
  
  METHODS
  The study was a randomised, controlled study. Of 298 primary screened patients 171 were eligible and randomised. Ninety-two patients adhered to follow-up investigations at 6 and 12 months. Main outcome measure was a sum score according to O'Brien calculated of five different questionnaires (BDI, SF-36, STAI, SCL 90R, F-SOZU-22).
  
  
  RESULTS
  The sum score for overall HRQOL did not show significant group differences at follow-up. Effects on HRQOL sub-dimensions within groups have been found. In the dimension of depression therapy group showed significant improvement from the first measurement to discharge from hospital (p < 0.001), 6 MFU (p = 0.004) and to 12 MFU (p = 0.013). Measures of anxiety showed significant improvement for the therapy group at discharge from hospital (p = 0.001). In the control group there was only a significant reduction in depression and anxiety from surgical ward to discharge (p = 0.013/p = 0.031).
  
  
  CONCLUSIONS
  Early onset cognitive therapy is not effective in improving overall HRQOL of severely injured patients but shows promising effects on depression and anxiety up to 12 months after trauma.
authors: Institute for Research in Operative Medicine (IFOM), Faculty of Medicine, University of Witten/Herdecke, Ostmerheimer Str. 200, 51109 Cologne, Germany.
authors: Nicola
authors: N
authors: Pirente
authors: Christine
authors: C
authors: Blum
authors: Silja
authors: S
authors: Wortberg
authors: Sevgi
authors: S
authors: Bostanci
authors: Eva
authors: E
authors: Berger
authors: Rolf
authors: R
authors: Lefering
authors: Bertil
authors: B
authors: Bouillon
authors: Klaus E
authors: KE
authors: Rehm
authors: Edmund A M
authors: EA
authors: Neugebauer
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001007:Anxiety / Q000523:psychology / Q000628:therapy; D015928:Cognitive Behavioral Therapy; D003863:Depression / Q000523:psychology / Q000628:therapy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015601:Injury Severity Score; D008297:Male; D008875:Middle Aged; D009104:Multiple Trauma / Q000523:psychology* / Q000601:surgery; D010351:Patient Discharge; D011788:Quality of Life / Q000523:psychology*; D014193:Trauma Centers; D055815:Young Adult