title: Analysis and characterization of alumina particles reinforced ultra high molecular weight polyethylene composite for acetabular cup.
abstract: Composites of ultra high molecular weight polyethylene (UHMWPE) reinforced with 5, 10 and 15 percent of alumina were prepared by a technique of uniform mixing and moulding. Acetabular cups were produced by compression moulding methods. A new walk simulator was also developed in-house for testing the tribological performances of these cups. The results from walk simulator tests are encouraging. Using a human walk simulator machine we did in vitro wear testing. Characterizations were performed to analyse the microstructure, composition, phase purity and crystalline by using XRD, DSC/TGA. Biocompatibility test was done by cytotoxicity, hemocompatibility and MTT assay methods. Biocompatibility tests gave hemolysis counts with these polymer composites well within the acceptable range and the results indicate a significant improvement in biocompatibility of the polymer composites over the in parent polymers.
authors: Mechanical Engineering Department, Jadavpur University, Kolkata, India. dhananjoy@mailcity.com
authors: D
authors: D
authors: Saha
authors: P K
authors: PK
authors: Bose
authors: A K
authors: AK
authors: Banthia
authors: S
authors: S
authors: Dhabal
mesh_terms: D000077:Acetabulum; D000537:Aluminum Oxide / Q000737:chemistry / Q000633:toxicity; D001672:Biocompatible Materials / Q000737:chemistry / Q000633:toxicity*; D002478:Cells, Cultured; D006461:Hemolysis / Q000187:drug effects; D006621:Hip Joint / Q000502:physiology; D006622:Hip Prosthesis; D006801:Humans; D066298:In Vitro Techniques; D008422:Materials Testing; D011095:Polyethylenes / Q000737:chemistry / Q000633:toxicity; D013314:Stress, Mechanical; D016138:Walking
chemical_list: D001672:Biocompatible Materials; D011095:Polyethylenes; C111601:ultra-high molecular weight polyethylene; D000537:Aluminum Oxide