title: Randomized clinical trial of perioperative systemic warming in major elective abdominal surgery.
abstract: BACKGROUND
  Hypothermia is common in the operating theatre and may increase susceptibility to postoperative complications. Intraoperative systemic warming has been shown to improve outcomes of surgery. This study aimed to examine the effects of additional perioperative systemic warming on postoperative morbidity.
  
  
  METHODS
  All patients admitted for elective major abdominal surgery and fulfilling the inclusion criteria were randomized into control or warming groups. Both groups were warmed during surgery, but patients in the warming group were additionally warmed 2 h before and after surgery using a conductive carbon polymer mattress.
  
  
  RESULTS
  The trial recruited 103 patients (56 in the control group, 47 in the warming group). Both groups were well matched for age, sex and clinical state. Patients in the warming group had lower blood loss (median 200 (range 5-1000) ml versus median 400 (range 50-2300) ml in the control group; P = 0.011) and complication rates (15 (32 per cent) of 47 versus 30 (54 per cent) of 56 in the control group; P = 0.027). There were three deaths; two in the control group (P = 0.566).
  
  
  CONCLUSIONS
  Extending systemic warming to the perioperative period had additional beneficial effects, with minimal additional cost and patient discomfort.
authors: Professorial Unit of Surgery, University Hospital of North Tees, Stockton-on-Tees TS19 8PE, UK. pwong23@hotmail.com
authors: P F
authors: PF
authors: Wong
authors: S
authors: S
authors: Kumar
authors: A
authors: A
authors: Bohra
authors: D
authors: D
authors: Whetter
authors: D J
authors: DJ
authors: Leaper
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001833:Body Temperature Regulation; D004066:Digestive System Diseases / Q000401:mortality / Q000601:surgery*; D013505:Digestive System Surgical Procedures / Q000379:methods / Q000401:mortality; D005260:Female; D006801:Humans; D006979:Hyperthermia, Induced / Q000379:methods*; D007035:Hypothermia / Q000517:prevention & control*; D007430:Intraoperative Care / Q000379:methods; D008297:Male; D008875:Middle Aged; D011182:Postoperative Care / Q000379:methods; D011183:Postoperative Complications / Q000401:mortality / Q000517:prevention & control*; D011300:Preoperative Care / Q000379:methods; D016896:Treatment Outcome