[Place of dietary protein restriction in the treatment of diabetic nephropathy].
The number of individuals with diabetes is rapidly growing worldwide, and in most countries, diabetic nephropathy has become the most important cause of ESRD. Although excessive protein intake may negatively influence the progression of renal disease, diabetics are rather reluctant to restrict their protein intake. However, in diabetic patients with renal failure, dietary protein restriction seems to have a beneficial effect on the course of the nephropathy without untoward effect on nutritional status. Moreover, the reduction in protein intake improves insulin sensitivity and has beneficial influences on different steps of carbohydrate metabolism. Dietary protein restriction should be considered as a safe therapy and deserves to be associated with the most important aspects of the medical management i.e. glycemic control and blood pressure control.
Aparicio
Michel
M
aparicio.michel@wanadoo.fr
D003928:Diabetic Nephropathies / Q000178:diet therapy*; D018753:Diet, Protein-Restricted; D019587:Dietary Supplements; D006801:Humans; D012307:Risk Factors