title: Cortical reorganization for response regulation with unilateral thalamic stroke detected by functional MRI.
abstract: To understand neural reorganization of response regulation after stroke, a 54-year-old woman with a chronic left thalamic stroke performed a task requiring decisions about the directionality of an arrow during cerebral functional magnetic resonance imaging. Her performance was compared to 13 matched healthy control subjects. Her behavioral responses were slower but as accurate. Bilateral frontal activations were observed in the right medial frontal gyrus (BA 9), left superior frontal gyrus (BA 45), and left frontal rectus gyrus (BA 11). Activation in the right medial frontal gyrus, along with activity in close proximity to the anterior cingulate cortex, was observed, which may reflect reorganization of activity after the loss of function of the anterior cingulate cortex.
authors: Laboratory of Neuropsychology, Department of Psychology, The University of Hong Kong, Hong Kong.
authors: Kenneth S L
authors: KS
authors: Yuen
authors: Tatia M C
authors: TM
authors: Lee
authors: Yau-Yau
authors: YY
authors: Wai
authors: Ho-Ling
authors: HL
authors: Liu
authors: Edith N H
authors: EN
authors: Mok
authors: Leonard S W
authors: LS
authors: Li
authors: Chetwyn C H
authors: CC
authors: Chan
mesh_terms: D002540:Cerebral Cortex / Q000473:pathology* / Q000503:physiopathology*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D009043:Motor Activity / Q000502:physiology; D009473:Neuronal Plasticity / Q000502:physiology*; D020127:Recovery of Function / Q000502:physiology; D020521:Stroke / Q000473:pathology* / Q000503:physiopathology*; D013788:Thalamus