Specificity of glutamate receptors in P2 synaptosomal fraction from rat brain cortex.
Specificity of glutamate receptors in the P2 synaptosomal fraction from the cerebral cortex of newborn rats was studied by measuring (45)Ca(2+) uptake by synaptosomes in the presence of agonists of ionotropic and metabotropic glutamate receptors. It was shown that P2 synaptosomal fraction from rat cortex contains NMDA receptors, kainate receptors, and group 1 metabotropic receptors.
Petrova
L N
LN
Laboratory of Neurochemistry of Physiologically Active Substances, Institute of Physiologically Active Substances, Russian Academy of Sciences, Chernogolovka, Moscow region. petrov@icp.ac.ru
Bachurin
S O
SO
D000818:Animals; D002118:Calcium / Q000378:metabolism; D002540:Cerebral Cortex / Q000378:metabolism*; D018690:Excitatory Amino Acid Agonists / Q000378:metabolism; D051381:Rats; D017208:Rats, Wistar; D017470:Receptors, Glutamate / Q000378:metabolism*; D018092:Kainic Acid Receptors / Q000378:metabolism; D018094:Receptors, Metabotropic Glutamate / Q000378:metabolism; D016194:Receptors, N-Methyl-D-Aspartate / Q000378:metabolism; D013574:Synaptosomes / Q000378:metabolism*
D002118:Calcium; D018690:Excitatory Amino Acid Agonists; D017470:Receptors, Glutamate; D018092:Kainic Acid Receptors; D018094:Receptors, Metabotropic Glutamate; D016194:Receptors, N-Methyl-D-Aspartate