Saccharomyces cerevisiae emboli in an immunocompromised patient with relapsed acute myeloid leukaemia.
In humans, Saccharomyces cerevisiae (baker's yeast) is found infrequently as a commensal of mucosal surfaces and rarely causes infections. We describe a case of cutaneous septic emboli developing in a patient with relapsing acute myeloid leukaemia M6 who had recently been treated with clofarabine. Yeast forms were seen on skin biopsy and S. cerevisiae was isolated from her Hickman line. We are not aware of any previous case reports of cutaneous emboli associated with this organism.
Williams
J S
JS
Department of Dermatology, King's College Hospital, London, UK. juliet.williams@kingsch.nhs.uk
Mufti
G J
GJ
Powell
S
S
Salisbury
J R
JR
Higgins
E M
EM
D000227:Adenine Nucleotides / Q000627:therapeutic use; D000970:Antineoplastic Agents / Q000627:therapeutic use; D001087:Arabinonucleosides / Q000627:therapeutic use; D000077866:Clofarabine; D003881:Dermatomycoses / Q000382:microbiology*; D005260:Female; D006801:Humans; D016867:Immunocompromised Host; D015470:Leukemia, Myeloid, Acute / Q000188:drug therapy / Q000276:immunology*; D008875:Middle Aged; D009894:Opportunistic Infections / Q000382:microbiology*; D012008:Recurrence; D012441:Saccharomyces cerevisiae / Q000302:isolation & purification
D000227:Adenine Nucleotides; D000970:Antineoplastic Agents; D001087:Arabinonucleosides; D000077866:Clofarabine