title: Study of the buffering capacity, pH and salivary flow rate in type 2 well-controlled and poorly controlled diabetic patients.
abstract: OBJECTIVE
  This study measured the flow rate, pH and buffering capacity of saliva from well- and poorly metabolically controlled Type 2 diabetic patients in three cities of the southern part of Brazil, compared with healthy individuals from the same cities.
  
  
  METHODS
  Whole saliva was collected by mechanical stimulation and buffering capacity and glucose level were measured. Blood was collected after 12 hours fasting and glucose and glycosylated haemoglobin concentrations were determined. The data were analysed by one-way ANOVA and Student-Newman-Keuls (alpha= 0.05).
  
  
  RESULTS
  The flow rate was lower in the Type 2 diabetic patients, regardless of whether they were well or poorly metabolically controlled, compared with healthy individuals (p < 0.05). Salivary glucose concentration was higher in both diabetic patient groups, i.e. well and poorly metabolically controlled, than in the control (p < 0.05).
  
  
  CONCLUSIONS
  The metabolic control of hyperglycaemia was not sufficient to improve the salivary flow rate or the salivary glucose concentration.
authors: University of Oeste de Santa Catarina, Campus Joaçaba, SC, Brazil.
authors: Maria José
authors: MJ
authors: Bernardi
authors: Alessandra
authors: A
authors: Reis
authors: Alessandro Dourado
authors: AD
authors: Loguercio
authors: Ruth
authors: R
authors: Kehrig
authors: Mariana Ferreira
authors: MF
authors: Leite
authors: José
authors: J
authors: Nicolau
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001786:Blood Glucose / Q000032:analysis; D002021:Buffers; D003924:Diabetes Mellitus, Type 2 / Q000097:blood / Q000503:physiopathology* / Q000517:prevention & control; D005215:Fasting; D005260:Female; D005947:Glucose / Q000032:analysis; D006442:Glycated Hemoglobin / Q000032:analysis; D006801:Humans; D006863:Hydrogen-Ion Concentration; D006943:Hyperglycemia / Q000097:blood / Q000517:prevention & control; D008297:Male; D008875:Middle Aged; D012463:Saliva / Q000737:chemistry / Q000378:metabolism / Q000502:physiology*; D012636:Secretory Rate / Q000502:physiology; D014987:Xerostomia / Q000503:physiopathology
chemical_list: D001786:Blood Glucose; D002021:Buffers; D005947:Glucose; D006442:Glycated Hemoglobin