Neurological morbidity and the pertussis vaccine: an old story revisited.
We describe 3 children with neurological disorders that developed in association with their receipt of the whole-cell pertussis vaccine. Newer studies supported the ability of the wP vaccine to adversely affect the CNS. The possibility that it worsened their clinical course in infancy by causing additional damage should not be disregarded.
Schupper
Aviv
A
Department of Neurology, Schneider Children's Medical Centre of Israel, Petah Tiqva, Sackler Faculty of Medicine, Tel Aviv University Tel aviv, Israel. AVINOAMS@clalit.org.il
Shuper
Avinoam
A
D000293:Adolescent; D002648:Child; D015721:Diphtheria-Tetanus-Pertussis Vaccine / Q000009:adverse effects*; D004827:Epilepsy / Q000150:complications* / Q000276:immunology; D005260:Female; D006801:Humans; D007115:Immunization Schedule; D007117:Immunization, Secondary / Q000009:adverse effects*; D008297:Male; D019636:Neurodegenerative Diseases / Q000150:complications* / Q000276:immunology; D010567:Pertussis Vaccine / Q000009:adverse effects*
D015721:Diphtheria-Tetanus-Pertussis Vaccine; D010567:Pertussis Vaccine