MRI-based modeling for evaluation of in vivo contact mechanics in the human wrist during active light grasp.
Investigations of in vivo joint mechanics are important for understanding the joint function under functional loading and the mechanisms of pathology. In this study we used magnetic resonance imaging (MRI) based joint contact modeling to evaluate in vivo joint contact mechanics in the human wrist. MRI scans were performed on the wrists of four subjects while they maintained light grasp of a cylinder, and with the same wrist relaxed. 3D models of the radius, scaphoid and lunate, including cartilage surface data, were constructed from the relaxed image data. These models were transformed into the loaded configuration, as determined from the grasp image data, and contact mechanics were evaluated. The resulting contact pressures, areas and forces were then analyzed for each articulation and for each subject. Contact areas were measured directly from grasp MRI images for comparison to the model predictions. The first-ever estimates for in vivo radioscaphoid and radiolunate contact pressure agreed reasonably well with previous cadaveric studies. This investigation also produced novel in vivo scapholunate contact results that were similar to radiolunate data. The specimen-specific contact area comparison generally showed substantial variability between the models and the direct measurements from MRI. On average, the models were within about 10% of the direct MRI measurements for radioscaphoid and scapholunate contact areas, but radiolunate contact areas from the model were only within 55% of the direct measurements. Overall, the results of the study suggest that MRI-based modeling has substantial potential for evaluation of in vivo joint contact mechanics, especially as technology and methodology improve.
Pillai
Ravi R
RR
Department of Mechanical Engineering, University of Kansas, Learned Hall 1530 W. 15th St., Room 3138 Lawrence, Kansas 66045-7609, USA.
Thoomukuntla
Bhaskar
B
Ateshian
Gerard A
GA
Fischer
Kenneth J
KJ
D000328:Adult; D005260:Female; D050276:Hand Bones / Q000000981:diagnostic imaging / Q000502:physiology*; D018737:Hand Strength / Q000502:physiology*; D006801:Humans; D021621:Imaging, Three-Dimensional; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D008954:Models, Biological; D011859:Radiography; D014953:Wrist / Q000000981:diagnostic imaging / Q000502:physiology*; D014955:Wrist Joint / Q000473:pathology / Q000502:physiology*