title: [Primary tumours of the external auditory canal. Our experience in 34 patients].
abstract: OBJECTIVE
  Malignant neoplasms of the external auditory canal (EAC) and middle ear are rare but have a poor prognosis. The aim of this study is to identify the variables associated with worse prognosis.
  
  
  METHODS
  Thirty-four patients were treated in our department between 1990 and 2006 for EAC and middle ear tumours. The patients were staged according to the 1990 Pittsburgh classification. In most cases, surgery was followed by post-operative radiotherapy.
  
  
  RESULTS
  The overall disease-free survival was 49 % after 5 years. It reached 87 % in stages I and II, whereas the survival for stages III and IV was 21 % (P=.001). Pre-operative facial nerve paralysis (P=.03), lymph node metastasis (P=.01) and dural extension (P=.02) were associated with decreased survival rates.
  
  
  CONCLUSIONS
  In carcinomas of the EAC and middle ear, lymph node involvement, facial nerve palsy, and dural extension were associated with a poorer outcome. For tumours in advanced stages, new therapeutic protocols should be evaluated.
authors: Servicio de Otorrinolaringología, Hospital Universitario Central de Asturias, Oviedo, Asturias, España.
authors: David
authors: D
authors: Lobo Duro
authors: José Luis
authors: JL
authors: Llorente Pendás
authors: Carlos
authors: C
authors: Suárez Nieto
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D004424:Ear Canal; D004428:Ear Neoplasms / Q000401:mortality* / Q000601:surgery*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012189:Retrospective Studies; D015996:Survival Rate