title: [Serum IL-12 level in mice infected with Trichinella spiralis].
abstract: Kunming mice were infected by feeding 150+/-5 larvae of Trichinella spiralis, established was also a normal control group. Blood was collected from the ophthalmic venous plexus respectively on 7 d, 21 d, 35 d and 49 d after infection and IL-12 in the serum was detected by ELISA. The level of IL-12 in serum decreased in groups of 7 d, 21 d, and 35 d, with a significant difference to the control (P<0.01). However, there was no significant difference between 49d group and control (P>0.05), suggesting that the serum IL-12 of the Trichinella spiralis-infected mice significantly decreased at the earlier stage but approached to normal at a later stage.
authors: Department of Parasitology, Zunyi Medical College, Zunyi 563003, China.
authors: Qi-Hui
authors: QH
authors: Wan
authors: Jia-Li
authors: JL
authors: Wang
authors: Li-Fang
authors: LF
authors: He
authors: Hui
authors: H
authors: Liu
authors: Xi
authors: X
authors: Zhang
mesh_terms: D000818:Animals; D004797:Enzyme-Linked Immunosorbent Assay; D006790:Host-Parasite Interactions; D018664:Interleukin-12 / Q000097:blood*; D007814:Larva / Q000502:physiology; D051379:Mice; D008815:Mice, Inbred Strains; D017160:Trichinella spiralis / Q000502:physiology*; D014235:Trichinellosis / Q000097:blood* / Q000469:parasitology*
chemical_list: D018664:Interleukin-12