title: Spontaneous closure of macular holes developed after pars plana vitrectomy.
abstract: OBJECTIVE
  To report a small, retrospective, noncomparative case series (3 patients) of idiopathic macular holes with spontaneous closure in previously vitrectomized eyes.
  
  
  METHODS
  The first patient developed a macular hole 14 months after vitrectomy for penetrating ocular trauma. In the rest of the patients, the macular holes were documented ten days and two months after vitrectomies for retinal detachment.
  
  
  RESULTS
  In all cases the macular holes resolved spontaneously 2 years, 6 and 9 months after their documentation, respectively.
  
  
  CONCLUSIONS
  Despite the limitations placed by the small sample of studied patients, it seems that spontaneous closure of macular holes developed after vitrectomy can happen as part of their natural course. Both pathogenetic and repair factors involved in macular hole can act spontaneously in a vitrectomized eye.
authors: University Eye Clinic, University of Crete Medical School, Greece. tsilimb@med.uoc.gr
authors: Miltiadis K
authors: MK
authors: Tsilimbaris
authors: Stratos
authors: S
authors: Gotzaridis
authors: Spyridon K
authors: SK
authors: Charisis
authors: Georgios
authors: G
authors: Kymionis
authors: Emmanouil V
authors: EV
authors: Christodoulakis
mesh_terms: D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D033401:Microscopy, Acoustic; D008875:Middle Aged; D011183:Postoperative Complications; D012075:Remission, Spontaneous; D012163:Retinal Detachment / Q000175:diagnosis / Q000601:surgery*; D012167:Retinal Perforations / Q000000981:diagnostic imaging / Q000209:etiology / Q000473:pathology*; D012189:Retrospective Studies; D041623:Tomography, Optical Coherence; D014821:Vitrectomy / Q000009:adverse effects*