title: New insights into the subversion of the chemokine system by poxviruses.
abstract: Viruses encode immune evasion mechanisms to survive in the immunocompetent host. Chemokines mediate the migration of immune cells and their critical role in immunity is emphasized by the numerous virus-encoded strategies to modulate their activity. Evidence published in this issue of the European Journal of Immunology uncovers novel mechanisms encoded by vaccinia virus to inhibit the chemokine-mediated migration of DC, an important event in the initiation of the immune response to viral infections.
authors: Centro de Biología Molecular Severo Ochoa, Campus Universidad Autónoma, Cantoblanco, Madrid, Spain. aalcami@cbm.uam.es
authors: Antonio
authors: A
authors: Alcami
mesh_terms: D018925:Chemokines / Q000037:antagonists & inhibitors* / Q000378:metabolism*; D006801:Humans; D011212:Poxviridae / Q000472:pathogenicity / Q000502:physiology*; D011213:Poxviridae Infections / Q000276:immunology* / Q000378:metabolism / Q000821:virology*
chemical_list: D018925:Chemokines