title: Effect of feeding T-2 toxin contaminated feed on the utilisation of vitamin E in chickens.
abstract: The purpose of the present study was to investigate the effect of experimental T-2 toxin load (2.35 mg/kg of feed) and vitamin E supply in the drinking water (10.5 mg/bird/day) on vitamin E levels of the blood plasma and liver in broiler chickens in a 14-day experiment. It was found that T-2 toxin load did not influence vitamin E content of the blood plasma except at day 3 after the toxin load when a moderate increase was detected in plasma vitamin E. No significant changes were found in vitamin E content of the liver. The simultaneous use of high-dose vitamin E supplementation and T-2 toxin load caused a significantly higher plasma vitamin E content but the changes were less expressed in the group subjected to T-2 toxin load. Vitamin E supply also resulted in a marked and significant increase in vitamin E concentrations of the liver on days 3 and 7 even in the T-2 loaded group, but this concentration significantly decreased thereafter. The results show that T-2 contamination of the diet has an adverse effect on the utilisation of vitamin E in broiler chickens.
authors: Department of Nutrition, Faculty of Agricultural and Environmental Sciences, Szent István University, H-2103 Gödöllo, Páter K. u. 1, Hungary.
authors: Maria
authors: M
authors: Weber
authors: S
authors: S
authors: Stiller
authors: K
authors: K
authors: Balogh
authors: L
authors: L
authors: Wágner
authors: Márta
authors: M
authors: Erdélyi
authors: M
authors: M
authors: Mézes
mesh_terms: D000821:Animal Feed / Q000506:poisoning*; D000818:Animals; D000975:Antioxidants / Q000493:pharmacokinetics*; D002645:Chickens / Q000378:metabolism*; D019587:Dietary Supplements; D004347:Drug Interactions; D008099:Liver / Q000378:metabolism; D008297:Male; D011201:Poultry Diseases / Q000378:metabolism*; D013605:T-2 Toxin / Q000494:pharmacology*; D014810:Vitamin E / Q000097:blood / Q000493:pharmacokinetics*
chemical_list: D000975:Antioxidants; D014810:Vitamin E; D013605:T-2 Toxin