Rhinoorbital and pulmonary zygomycosis post pulmonary aspergilloma in a patient with chronic lymphocytic leukaemia.
A patient with an 18-year history of chronic lymphocytic leukaemia developed zygomycosis of the orbit, sinuses and nasal bones together with pulmonary fungal nodes due to Absidia corymbifera while on high dose steroids and four months after successful treatment of pulmonary aspergilloma with liposomal amphotericin B followed by oral voriconazole. He was treated successfully with extensive surgical debridement, intravenous liposomal amphotericin B and intravenous itraconazole.
Barr
Andrew
A
Department of Haematology, Chelsea and Westminster Hospital, London, UK.
Nolan
Marianne
M
Grant
William
W
Costello
Christine
C
Petrou
Michael A
MA
D020095:Absidia; D001228:Aspergillosis / Q000150:complications*; D006801:Humans; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000150:complications*; D008172:Lung Diseases, Fungal / Q000150:complications*; D008297:Male; D008875:Middle Aged; D009091:Mucormycosis / Q000150:complications*; D009916:Orbital Diseases / Q000209:etiology* / Q000382:microbiology* / Q000628:therapy; D010254:Paranasal Sinus Diseases / Q000209:etiology* / Q000382:microbiology* / Q000628:therapy; D020096:Zygomycosis / Q000209:etiology* / Q000628:therapy