Estimation of macular pigment optical density in the elderly: test-retest variability and effect of optical blur in pseudophakic subjects.
The reproducibility of macular pigment optical density (MPOD) estimates in the elderly was assessed in 40 subjects (age: 79.1+/-3.5). Test-retest variability was good (Pearson's r coefficient: 0.734), with an average coefficient of variation (CV) of 18.4% and an intraclass correlation coefficient (ICC) of 0.96. The effect of optical blur on MPOD estimates was investigated in 22 elderly pseudophakic subjects (age: 79.9+/-3.6) by comparing the baseline MPOD, obtained with an optimal correction, with MPODs obtained with a +/-1.00-diopter optical blur. This optical blur did not cause differences in the MPOD estimates, its accuracy, or test duration.
Gallaher
Kevin T
KT
Department of Ophthalmology, Hamilton Eye Institute, University of Tennessee Health Science Center, 930 Madison Avenue, Suite 731, Memphis, TN 38163, USA.
Mura
Marco
M
Todd
Wm Andrew
WA
Harris
Tarsha L
TL
Kenyon
Emily
E
Harris
Tamara
T
Johnson
Karen C
KC
Satterfield
Suzanne
S
Kritchevsky
Stephen B
SB
Iannaccone
Alessandro
A
D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000502:physiology*; D003941:Diagnostic Techniques, Ophthalmological; D005260:Female; D006801:Humans; D008266:Macula Lutea / Q000737:chemistry; D008297:Male; D008875:Middle Aged; D055095:Optics and Photonics; D010783:Photometry / Q000379:methods; D019591:Pseudophakia / Q000503:physiopathology*; D015203:Reproducibility of Results; D012168:Retinal Pigments / Q000032:analysis*; D014792:Visual Acuity
D012168:Retinal Pigments