Circulating serotypes and antimicrobial sensitivity of Streptococcus pyogenes isolates from children in Cyprus.
The most common T-serotypes among group A streptococci (n = 88) isolated from pharyngeal samples of children referred to a tertiary hospital in Cyprus for pharyngitis or scarlet fever during a 14-month period (2003-2004) were T28 (25%), T8/25/Imp19 (22.7%) and T12 (9.1%). All 88 isolates were sensitive to penicillin and clindamycin, but 1.1% and 18.2% of isolates were resistant to erythromycin and tetracycline, respectively. Macrolide consumption was estimated at 1.7 defined daily doses/1000 inhabitants/day. The low percentage of resistance to macrolides may have been related, at least in part, to the low consumption of macrolides.
Koliou
M
M
Infectious Diseases Research Laboratory, Department of Pediatrics, Archbishop Makarios Hospital, Nicosia, Cyprus. mkoliou@spidernet.com.cy
Ioannou
Y
Y
Efstratiou
A
A
Hannidou
N
N
Pieri
V
V
Alexandrou
M
M
Soteriades
E S
ES
D000293:Adolescent; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D002648:Child; D002675:Child, Preschool; D003535:Cyprus; D024881:Drug Resistance, Bacterial; D005260:Female; D006801:Humans; D007223:Infant; D018942:Macrolides / Q000627:therapeutic use; D008297:Male; D008826:Microbial Sensitivity Tests; D010612:Pharyngitis / Q000382:microbiology; D010614:Pharynx / Q000382:microbiology; D012541:Scarlet Fever / Q000382:microbiology; D012703:Serotyping; D013290:Streptococcal Infections / Q000382:microbiology*; D013297:Streptococcus pyogenes / Q000145:classification* / Q000187:drug effects / Q000302:isolation & purification*
D000900:Anti-Bacterial Agents; D018942:Macrolides