The heart's Da Vinci code: a Renaissance at Keystone.
At a recent Keystone symposium on "Molecular Pathways in Cardiac Development and Disease" in Colorado, significant advances in the understanding of heart development were discussed. The identification and isolation of cardiovascular progenitors, their modulation by secreted factors, and some tantalizing insights into cardiac regeneration were some of the highlights of what was characterized by some as a renaissance in cardiovascular development.
Bruneau
Benoit G
BG
Gladstone Institute of Cardiovascular Disease and Department of Pediatrics, University of California, San Francisco, CA 94158, USA. bbruneau@gladstone.ucsf.edu
Black
Brian L
BL
D000818:Animals; D002454:Cell Differentiation; D005786:Gene Expression Regulation; D006321:Heart / Q000196:embryology / Q000254:growth & development / Q000502:physiology; D006801:Humans; D035683:MicroRNAs; D039902:Multipotent Stem Cells / Q000166:cytology*; D009206:Myocardium / Q000166:cytology* / Q000378:metabolism; D032383:Myocytes, Cardiac / Q000166:cytology*; D034622:RNA Interference; D012038:Regeneration; D014158:Transcription, Genetic; D051153:Wnt Proteins / Q000378:metabolism
D035683:MicroRNAs; D051153:Wnt Proteins