title: Clinical and metabolic features of polycystic ovary syndrome.
abstract: OBJECTIVE
  To explore the clinical and metabolic features of Chinese women with polycystic ovary syndrome (PCOS).
  
  
  METHODS
  The clinical data of 273 Chinese women diagnosed as having PCOS were retrospectively studied.
  
  
  RESULTS
  Of these women 34.8% had hirsutism, 45.1% had acne, 94.1% had some menstrual abnormality, and 96.7% had typical appearances of polycystic ovaries on ultrasonographic examination. The prevalence of overweight women was 30.4%, and the prevalence of insulin resistance was 12.8% using the glucose to insulin ratio (GIR) and 21.6% using the homesostasis model assessment (HOMA). Body mass index was significantly correlated with fasting insulin level (r=0.50), GIR (r=0.37) and HOMA (r=0.53).
  
  
  CONCLUSIONS
  Menstrual abnormality and polycystic ovaries were the main clinical manifestations in this cohort of Chinese women with PCOS. The prevalence of hyperandrogenism, obesity, and insulin resistance was lower in this cohort than in women from other races with the same condition. Ethnic differences needs to be considered when studying the clinical and metabolic features of women with PCOS.
authors: Department of Obstetrics and Gynecology, Second Affiliated Hospital of Sun Yat-sen University, Guangzhou Guangdong, China.
authors: Lin
authors: L
authors: Li
authors: Dongzi
authors: D
authors: Yang
authors: Xiaoli
authors: X
authors: Chen
authors: Yaxiao
authors: Y
authors: Chen
authors: Shuying
authors: S
authors: Feng
authors: Liangan
authors: L
authors: Wang
mesh_terms: D000293:Adolescent; D000328:Adult; D001786:Blood Glucose; D015992:Body Mass Index; D002681:China / Q000453:epidemiology; D005260:Female; D006801:Humans; D017588:Hyperandrogenism / Q000453:epidemiology / Q000209:etiology; D007328:Insulin / Q000097:blood; D007333:Insulin Resistance / Q000502:physiology*; D008599:Menstruation Disturbances / Q000453:epidemiology / Q000209:etiology; D050177:Overweight; D011085:Polycystic Ovary Syndrome / Q000150:complications* / Q000503:physiopathology; D012189:Retrospective Studies
chemical_list: D001786:Blood Glucose; D007328:Insulin