title: Predictors of diffuse renal microembolization following endovascular repair of abdominal aortic aneurysms.
abstract: We evaluated the incidence, risk factors, and clinical consequences of renal microembolic events following endovascular aneurysm repair using suprarenal or infrarenal fixation. Pre- and postoperative (1 month) computed tomographic angiograms were reviewed for new renal perfusion defects. Suprarenal aortic and infrarenal neck thrombus load was classified by circumference involved and thrombus thickness. Serum creatinine was measured preoperatively, on the first postoperative day, and 1 month postoperatively. Among 136 patients, 8 (5.9%) had bilateral microembolic cortical defects. Patients with moderate or severe suprarenal thrombus were more likely to have renal microemboli than those with no or mild suprarenal thrombus (17% vs 0%; p < .001). Similarly, patients with moderate or severe infrarenal neck thrombus were more likely to have renal microemboli than those with no or mild infrarenal thrombus (9.6% vs 1.5%; p = .08). Severe infrarenal thrombus was independently predictive of microembolization (odds ratio 15.0; 95% confidence interval 1.6-142; p = .018). There was no statistically significant difference in the incidence of renal microembolization when comparing suprarenal and infrarenal fixation (8.2% vs 4.0%; p = .47). Changes in creatinine from baseline were not different in those with or without renal microemboli. Renal microembolization is an uncommon but distinct radiographic finding that is more associated with significant neck thrombus than fixation level.
authors: Division of Vascular Surgery, University of Pittsburgh Medical Center, 200 Lothrop Street, Pittsburgh, PA 15213, USA.
authors: Tamer N
authors: TN
authors: Boules
authors: Stephen F
authors: SF
authors: Stanziale
authors: Admir
authors: A
authors: Chomic
authors: Faith
authors: F
authors: Selzer
authors: Mitchell E
authors: ME
authors: Tublin
authors: Michel S
authors: MS
authors: Makaroun
mesh_terms: D000368:Aged; D017130:Angioplasty / Q000379:methods; D001012:Aorta, Abdominal / Q000601:surgery*; D017544:Aortic Aneurysm, Abdominal / Q000097:blood / Q000601:surgery*; D003404:Creatinine / Q000097:blood; D004617:Embolism / Q000097:blood / Q000000981:diagnostic imaging / Q000209:etiology*; D005260:Female; D006801:Humans; D007668:Kidney / Q000098:blood supply* / Q000000981:diagnostic imaging; D008297:Male; D011183:Postoperative Complications / Q000209:etiology*; D012307:Risk Factors; D014057:Tomography, X-Ray Computed / Q000379:methods
chemical_list: D003404:Creatinine