Molecular characterization of equine herpesvirus 1 (EHV-1) isolated from cattle indicating no specific mutations associated with the interspecies transmission.
Interspecies trasmission of equine herpesvirus 1 (EHV-1) from horse to cattle was shown by Crandell et al. (1988). Specific mutations related to the transmission were studied by comparison of five EHV-1 isolates in cattle (BH1247, 3M20-3, G118, G1753, and 9BSV4) using polymerase chain reaction and restriction fragment length polymorphism analysis with added sequencing. G118 and 3M20-3 were the genome type EHV-1 P, while G1753 was the genome type EHV-1 B. BH1247 and 9BSV4 might be other genome types. We could not identify specific mutations related to the interspecies transmission.
Pagamjav
Ochir
O
Department of Applied Veterinary Sciences, United Graduate School of Veterinary Sciences, Gifu University, Gifu, Japan.
Yamada
Souichi
S
Ibrahim
El-Sayed M
el-SM
Crandell
Robert A
RA
Matsumura
Tomio
T
Yamaguchi
Tsuyoshi
T
Fukushi
Hideto
H
D000818:Animals; D001483:Base Sequence; D002417:Cattle; D002418:Cattle Diseases / Q000635:transmission / Q000821:virology*; D006224:Cricetinae; D016172:DNA Fingerprinting; D022761:Gene Transfer, Horizontal; D006566:Herpesviridae Infections / Q000635:transmission / Q000821:virology*; D004861:Herpesvirus 1, Equid / Q000235:genetics* / Q000302:isolation & purification / Q000472:pathogenicity; D006736:Horses; D008969:Molecular Sequence Data; D009154:Mutation; D016133:Polymerase Chain Reaction / Q000379:methods; D012150:Polymorphism, Restriction Fragment Length; D014774:Virulence