Nephrotic syndrome as a complication of intravesical BCG treatment of transitional cell carcinoma of urinary bladder.
Nephrotic syndrome can be associated with various neoplasms, especially solid tumors and lymphomas. This patient presented with painless hematuria of transitional cell carcinoma of urinary bladder, underwent transurethral resection, but developed recurrence 16 months later. Repeat resection was done and intravesical Bacillus Calmette-Guerin (BCG) injections were started. After six months, the patient developed hypertension and nephrotic syndrome with a biopsy revealing membranous glomerulonephritis, though there was no radiological evidence of tumor. This is the first case of nephrotic syndrome with intravesical BCG instillation in a bladder carcinoma patient.
Singh
N P
NP
Department of Medicine, Maulana Azad Medical College & Lok Nayak Hospital, New Delhi, India.
Prakash
Anupam
A
Kubba
Samir
S
Ganguli
Anirban
A
Agarwal
S K
SK
Dinda
Amit K
AK
Aggarwal
P N
PN
D001500:BCG Vaccine / Q000009:adverse effects*; D002295:Carcinoma, Transitional Cell / Q000276:immunology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009404:Nephrotic Syndrome / Q000209:etiology*; D011239:Prednisolone / Q000627:therapeutic use; D016896:Treatment Outcome; D001749:Urinary Bladder Neoplasms / Q000276:immunology*
D001500:BCG Vaccine; D011239:Prednisolone