Antepartum transabdominal amnioinfusion.
OBJECTIVE
To determine the usefulness of antepartum transabdominal amnioinfusion (APTA) in reducing perinatal morbidity and mortality due to oligohydramnios.


METHODS
In this case-control study of 100 pregnant women with oligohydramnios, 50 received APTA and 50 were treated conservatively. These controls were matched for age, parity, and pregnancy duration with the case patients.


RESULTS
There was a mean 4.02-cm increase in amniotic fluid index (AFI) after amnioinfusion. Only 18% of case patients required cesarean sections vs. 46% of controls. The perinatal mortality rate was 18% among controls and 4% among case patients, and the difference was significant.


CONCLUSIONS
Antepartum amnioinfusion is a useful procedure to reduce complications resulting from decreased intra-amniotic volume. It is especially useful in preterm pregnancies, where the procedure allows for a better perinatal outcome by prolonging the duration of pregnancy.
Chhabra
S
S
Department of Obstetrics and Gynaecology, Mahatma Gandhi Institute of Medical Sciences, 442 102, Wardha Sewagram, Maharashtra, India. chhabra_s@rediffmail.com
Dargan
R
R
Nasare
M
M
D000650:Amnion; D000653:Amniotic Fluid / Q000187:drug effects*; D016022:Case-Control Studies; D005260:Female; D005440:Fluid Therapy; D005865:Gestational Age; D006801:Humans; D007194:India / Q000453:epidemiology; D007226:Infant Mortality; D007231:Infant, Newborn; D007267:Injections; D007552:Isotonic Solutions / Q000008:administration & dosage*; D016104:Oligohydramnios / Q000401:mortality / Q000628:therapy*; D011247:Pregnancy; D011263:Pregnancy Trimester, Third; D000077325:Ringer's Lactate; D016896:Treatment Outcome
D007552:Isotonic Solutions; D000077325:Ringer's Lactate