Fatal Staphylococcus aureus haemorrhagic pneumonia producing Panton-Valentine leucocidin.
We present 2 cases of community acquired S. aureus pneumonia carrying Panton Valentine leucocidin (PVL). These cases illustrate this clinical entity characterized by a younger and healthier population than usual staphylococcal pneumonias and complicated by a 75% mortality rate. We also discuss the diagnosis and therapeutic difficulties.
Hyvernat
Herve
H
From the Medical Intensive Care Unit, Hôpital Universitaire Archet, Nice, France. hyvernat.h@chu-nice.fr
Pulcini
Celine
C
Carles
Danielle
D
Roques
Adrien
A
Lucas
Philippe
P
Hofman
Veronique
V
Hofman
Paul
P
Bernardin
Gilles
G
D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001427:Bacterial Toxins / Q000378:metabolism*; D005098:Exotoxins / Q000378:metabolism*; D017809:Fatal Outcome; D005260:Female; D006470:Hemorrhage / Q000382:microbiology*; D006801:Humans; D007956:Leukocidins / Q000378:metabolism*; D008297:Male; D018410:Pneumonia, Bacterial / Q000150:complications / Q000188:drug therapy / Q000382:microbiology*; D013203:Staphylococcal Infections / Q000188:drug therapy / Q000382:microbiology*; D013211:Staphylococcus aureus / Q000378:metabolism*
D000900:Anti-Bacterial Agents; D001427:Bacterial Toxins; D005098:Exotoxins; D007956:Leukocidins; C078284:Panton-Valentine leukocidin