title: Isomeric enhancement of davanone from natural davana oil aided by supercritical carbon dioxide.
abstract: The chemical nature of davanone isolated from natural davana oil via packed column preparative supercritical fluid chromatography with a carbon dioxide-based mobile phase has been defined. Analyses used to characterize davanone included nuclear magnetic resonance spectroscopy, optical rotation, mass spectrometry, headspace solid-phase microextraction, enantiomeric purity via gas chromatography (GC), and GC-coupled olfactometry. For comparison, natural davana oil was subjected to the same types of measurements. The enriched davanone sample was nearly 100% optically pure. This indicates that fractionation of the davana oil with supercritical fluids at near room temperature had little effect on the optical integrity of the sample.
authors: R. J. Reynolds Tobacco Company, Winston Salem, North Carolina 27102-1487, USA.
authors: William Monroe
authors: WM
authors: Coleman
authors: Michael Frances
authors: MF
authors: Dube
authors: Mehdi
authors: M
authors: Ashraf-Khorassani
authors: Larry Thomas
authors: LT
authors: Taylor
mesh_terms: D019306:Artemisia / Q000737:chemistry*; D002849:Chromatography, Gas; D025924:Chromatography, Supercritical Fluid; D008401:Gas Chromatography-Mass Spectrometry; D007536:Isomerism; D009682:Magnetic Resonance Spectroscopy; D010938:Plant Oils / Q000737:chemistry*; D012717:Sesquiterpenes / Q000737:chemistry*; D012903:Smell; D013237:Stereoisomerism
chemical_list: D010938:Plant Oils; D012717:Sesquiterpenes; C520072:davanone