title: Use of antibiotic cement rod to treat intramedullary infection after nailing: preliminary study in 19 patients.
abstract: The treatment of intramedullary infections after nailing usually includes removal of the nail, debridement, and, in some cases, insertion of antibiotic-impregnated cement beads. We use this self-made antibiotic cement rod to treat intramedullary infections. Compared with the beads, it provides some limited mechanical support and can be preserved in the canal for a long time. We reviewed 19 infected patients who underwent removal of the nails, excision of sinus tracks, debridement of the canal and insertion of the rods. No recurrent infection occurred in 18 cases and 11 cases achieved bone healing, 6 cases achieved partial union. One patient had nonunion and one patient underwent amputation because of severe primary trauma and long-term infection. The rod was removed between 35 and 123 days after implantation. We conclude that the antibiotic cement rods could be a relatively effective, simple and inexpensive method of treating intramedullary infections after nailing.
authors: Department of Orthopaedics, Second Affiliated Hospital, Medical College, Zhejiang University, Hangzhou, PR China. zhq1967@hotmail.com
authors: Zheng
authors: Z
authors: Qiang
authors: Pan Zhi
authors: PZ
authors: Jun
authors: Xu Jian
authors: XJ
authors: Jie
authors: Li
authors: L
authors: Hang
authors: Li Jian
authors: LJ
authors: Bing
authors: Li Fang
authors: LF
authors: Cai
mesh_terms: D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000008:administration & dosage*; D001843:Bone Cements; D001858:Bone Nails; D003646:Debridement; D005260:Female; D005264:Femoral Fractures / Q000601:surgery; D005594:Fracture Fixation, Intramedullary / Q000295:instrumentation*; D017102:Fracture Healing; D006801:Humans; D008297:Male; D008875:Middle Aged; D010019:Osteomyelitis / Q000188:drug therapy*; D019904:Polymethyl Methacrylate; D011183:Postoperative Complications; D011474:Prosthesis Design; D013203:Staphylococcal Infections / Q000188:drug therapy; D013211:Staphylococcus aureus; D013978:Tibial Fractures / Q000601:surgery; D016896:Treatment Outcome; D014640:Vancomycin / Q000008:administration & dosage*
chemical_list: D000900:Anti-Bacterial Agents; D001843:Bone Cements; D014640:Vancomycin; D019904:Polymethyl Methacrylate