Neurofibromatosis 1, and Not TP53, seems to be the main target of chromosome 17 deletions in de novo acute myeloid leukemia.
Suela
Javier
J
Largo
Cristina
C
Ferreira
Bibiana
B
Alvarez
Sara
S
Robledo
Mercedes
M
González-Neira
Anna
A
Calasanz
Maria José
MJ
Cigudosa
Juan C
JC
D000208:Acute Disease; D002886:Chromosomes, Human, Pair 17; D017353:Gene Deletion; D020869:Gene Expression Profiling; D015973:Gene Expression Regulation, Leukemic; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D007951:Leukemia, Myeloid / Q000235:genetics*; D019656:Loss of Heterozygosity; D009456:Neurofibromatosis 1 / Q000235:genetics*; D020411:Oligonucleotide Array Sequence Analysis; D015203:Reproducibility of Results; D016159:Tumor Suppressor Protein p53 / Q000235:genetics*
C495901:TP53 protein, human; D016159:Tumor Suppressor Protein p53