title: Isolation and structural determination of sorbinols A and B, new triterpenes from Sorbus cashmariana, by 1D and 2D NMR spectroscopy.
abstract: Two new pentacyclic triterpenes, sorbinols A (1) and B (2) have been isolated from the ethyl acetate fraction of Sorbus cashmariana and their structures assigned from (1)H and (13)C NMR spectra, DEPT and by 2D COSY, NOE, HMQC and HMBC experiments. Both 1 and 2 showed moderate inhibitory potential against the enzyme lipoxygenase.
authors: Department of Applied Chemistry, University of Karachi, Karachi-75270, Pakistan.
authors: Mehdi Hassan
authors: MH
authors: Kazmi
authors: Ejaz
authors: E
authors: Ahmed
authors: Saira
authors: S
authors: Hameed
authors: Abdul
authors: A
authors: Malik
authors: Muhammad
authors: M
authors: Ashraf
mesh_terms: D004791:Enzyme Inhibitors / Q000737:chemistry; D008084:Lipoxygenase / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D015394:Molecular Structure; D010936:Plant Extracts / Q000737:chemistry; D031994:Sorbus / Q000737:chemistry*; D014315:Triterpenes / Q000737:chemistry*
chemical_list: D004791:Enzyme Inhibitors; D010936:Plant Extracts; D014315:Triterpenes; C521456:sorbinol A; C521457:sorbinol B; D008084:Lipoxygenase