title: Neuroprotective effects of vitamin E in cold induced cerebral injury in guinea pigs.
abstract: Significant reduction in hemorrhage (10 v/s 13), necrosis (2 v/s 4), cavitations (7 v/s 13), neuronal degeneration, perivascular and parenchymal inflammatory infiltrate (7 v/s 11) were observed in Vitamin E treated cold induced head injury in guinea pigs, evaluated post injury using the modified Benderson's scale. The results suggest that Vitamin E is highly effective in promoting clinical and histopathological recovery in cold induced head injury in guinea pigs.
authors: Department of Neurosurgery, Lokmanya Tilak Municipal Medical College & General Hospital, Sion, Mumbai 400 022, India. prernabadhe@yahoo.co.in
authors: Prerna
authors: P
authors: Badhe
authors: Jayant
authors: J
authors: Thorat
authors: Batuk D
authors: BD
authors: Diyora
authors: Ravikrishna
authors: R
authors: Mamidanna
authors: Parag
authors: P
authors: Sayal
authors: Suvarna
authors: S
authors: Badhe
authors: Alok K
authors: AK
authors: Sharma
mesh_terms: D000818:Animals; D000975:Antioxidants / Q000627:therapeutic use*; D001921:Brain / Q000473:pathology; D001930:Brain Injuries / Q000188:drug therapy* / Q000473:pathology; D003080:Cold Temperature; D005260:Female; D006168:Guinea Pigs; D008297:Male; D018696:Neuroprotective Agents / Q000627:therapeutic use*; D011897:Random Allocation; D014810:Vitamin E / Q000627:therapeutic use*
chemical_list: D000975:Antioxidants; D018696:Neuroprotective Agents; D014810:Vitamin E