Hepatoprotective and antioxidant activity of meadowsweet extract during experimental toxic hepatitis.
The extract of meadowsweet aerial parts exhibits hepatoprotective and antioxidant activity during experimental toxic CCl(4) hepatitis. This extract improved liver function. Meadowsweet extract in 70% ethanol (100 mg/kg) was most potent and exhibited low toxicity. By several parameters the effectiveness of this extract surpassed that of Carsil.
Shilova
I V
IV
Department of Biochemistry and Spectral Analysis, Central Research Laboratory, Siberian State Medical University, Tomsk. licvostok@mail.tomsknet.ru
Zhavoronok
T V
TV
Suslov
N I
NI
Krasnov
E A
EA
Novozheeva
T P
TP
Veremeev
A V
AV
Nagaev
M G
MG
Petina
G V
GV
D000818:Animals; D000975:Antioxidants / Q000494:pharmacology / Q000627:therapeutic use*; D002251:Carbon Tetrachloride / Q000633:toxicity; D056486:Chemical and Drug Induced Liver Injury / Q000188:drug therapy*; D031984:Filipendula / Q000737:chemistry*; D008099:Liver / Q000187:drug effects* / Q000503:physiopathology; D008297:Male; D008517:Phytotherapy / Q000379:methods*; D010936:Plant Extracts / Q000494:pharmacology / Q000627:therapeutic use*; D051381:Rats
D000975:Antioxidants; D010936:Plant Extracts; D002251:Carbon Tetrachloride