Smooth muscle hamartoma of the hard palate.
A small polypoid lesion was removed from the incisive papilla region of a healthy female aged 8 years. It was composed of non-cycling smooth muscle fibres that were immunoreactive for various muscle antigens, surrounded by basement membrane containing collagen IV, arranged as bundles and mixed with CD34(+) interstitial cells, mast cells, dendrocytes and nerves. The lesion could be attributed to dysgenesis affecting media of vessels emerging from the incisive foramen. Intra-oral smooth muscle hamartomas tend to favour regions featuring complex developmental events.
Zaitoun
H
H
Paediatric Dentistry, Department and School of Dental Studies, The University of Liverpool, Liverpool, UK.
Triantfyllou
A
A
D000199:Actins / Q000032:analysis; D018952:Antigens, CD34 / Q000032:analysis; D002148:Calmodulin-Binding Proteins / Q000032:analysis; D002648:Child; D024141:Collagen Type IV / Q000032:analysis; D003893:Desmin / Q000032:analysis; D005260:Female; D006222:Hamartoma / Q000473:pathology*; D006801:Humans; D007150:Immunohistochemistry; D009130:Muscle, Smooth / Q000473:pathology*; D021362:Palate, Hard / Q000473:pathology*; D009418:S100 Proteins / Q000032:analysis
D000199:Actins; D018952:Antigens, CD34; D002148:Calmodulin-Binding Proteins; D024141:Collagen Type IV; D003893:Desmin; D009418:S100 Proteins