Inhibition of myc promoter and telomerase activity and induction of delayed apoptosis by SYUIQ-5, a novel G-quadruplex interactive agent in leukemia cells.
Liu
J-N
JN
Deng
R
R
Guo
J-F
JF
Zhou
J-M
JM
Feng
G-K
GK
Huang
Z-S
ZS
Gu
L-Q
LQ
Zeng
Y-X
YX
Zhu
X-F
XF
D000970:Antineoplastic Agents / Q000494:pharmacology*; D017209:Apoptosis / Q000187:drug effects; D004247:DNA; D003959:Diamines / Q000494:pharmacology*; D054856:G-Quadruplexes; D016259:Genes, myc / Q000187:drug effects; D006801:Humans; D007938:Leukemia / Q000188:drug therapy* / Q000473:pathology*; D011401:Promoter Regions, Genetic / Q000187:drug effects; D011804:Quinolines / Q000494:pharmacology*; D019098:Telomerase / Q000187:drug effects
D000970:Antineoplastic Agents; D003959:Diamines; C521094:N'-(10H-indolo(3,2-b)quinolin-11-yl)-N,N-dimethylpropane-1,3-diamine; D011804:Quinolines; D004247:DNA; D019098:Telomerase