title: Iridoid glycosides from the stems of Pithecoctenium crucigerum (Bignoniaceae).
abstract: Sixteen crude extracts from six Panamanian plants of the family Bignoniaceae were submitted to rapid TLC tests against DPPH and acetylcholinesterase. Pithecoctenium crucigerum (L.) A.H. Gentry, which showed interesting activity against DPPH, has been studied. The chemical investigation of the methanol extract from the stems afforded the iridoid glycoside theviridoside and three derivatives (6'-O-cyclopropanoyltheviridoside, 10-O-hydroxybenzoyltheviridoside and 10-O-vanilloyltheviridoside), along with five known phenylethanoid glycosides (verbascoside, isoverbascoside, forsythoside B, jionoside D and leucosceptoside B). These last compounds were all active against DPPH. The structures were determined by means of spectrometric and chemical methods, including 1D and 2D NMR experiments and MS analysis.
authors: Laboratory of Pharmacognosy and Phytochemistry, School of Pharmaceutical Sciences, University of Geneva, University of Lausanne, Quai Ernest-Ansermet 30, CH-1211 Geneva 4, Switzerland.
authors: Frédéric
authors: F
authors: Martin
authors: Anne-Emmanuelle
authors: AE
authors: Hay
authors: Laura
authors: L
authors: Corno
authors: Mahabir P
authors: MP
authors: Gupta
authors: Kurt
authors: K
authors: Hostettmann
mesh_terms: D029402:Bignoniaceae / Q000737:chemistry*; D039823:Iridoids / Q000737:chemistry* / Q000302:isolation & purification*; D015394:Molecular Structure; D018547:Plant Stems / Q000737:chemistry*
chemical_list: D039823:Iridoids