A high-fat meal increases cardiovascular reactivity to psychological stress in healthy young adults.
The consumption of high levels of saturated fat over the course of several weeks may lead to exaggerated cardiovascular reactivity. The consumption of a single high-fat meal has been associated with a transient impairment of vascular function. In a randomized, repeated measures, crossover study we tested whether the consumption of a single high-fat meal by healthy, normotensive participants would affect cardiovascular reactivity when compared with an isocaloric, low-fat meal. Thirty healthy participants ate a high-fat (42 g) and a low-fat (1 g) meal on 2 separate occasions, and their cardiovascular response to 2 standard laboratory stressors was measured. Systolic blood pressure, diastolic blood pressure, and total peripheral resistance were greater in participants following the consumption of the high-fat meal relative to the low-fat meal. The findings of the present study are consistent with the hypothesis that even a single high-fat meal may be associated with heightened cardiovascular reactivity to stress and offer insight into the pathways through which a high-fat diet may affect cardiovascular function.
Jakulj
Fabijana
F
University of Calgary, Department of Psychology, Calgary, AB, Canada T2N 1N4.
Zernicke
Kristin
K
Bacon
Simon L
SL
van Wielingen
Laura E
LE
Key
Brenda L
BL
West
Sheila G
SG
Campbell
Tavis S
TS
D000328:Adult; D000704:Analysis of Variance; D001794:Blood Pressure / Q000187:drug effects; D002319:Cardiovascular System / Q000187:drug effects* / Q000503:physiopathology*; D018592:Cross-Over Studies; D003971:Diastole; D004041:Dietary Fats / Q000008:administration & dosage* / Q000494:pharmacology; D004305:Dose-Response Relationship, Drug; D005260:Female; D006801:Humans; D008297:Male; D013315:Stress, Psychological / Q000503:physiopathology*; D013599:Systole; D014655:Vascular Resistance / Q000187:drug effects
D004041:Dietary Fats