A left-handed supramolecular assembly around a right-handed screw axis in the crystal structure of homo-DNA.
Duplexes of homo-DNA, a hexose analogue of DNA and autonomous pairing system, exhibit unusual conformational features, and in the crystal structure create a unique double-helical supramolecular motif whose main characteristic is a handedness that is opposite to that of the underlying crystallographic symmetry.
Pallan
Pradeep S
PS
Department of Biochemistry, School of Medicine, Vanderbilt University, Nashville, TN 37232, USA.
Lubini
Paolo
P
Egli
Martin
M
D020029:Base Pairing; D003461:Crystallography; D004247:DNA / Q000737:chemistry*; D006601:Hexoses / Q000737:chemistry*; D006860:Hydrogen Bonding; D009690:Nucleic Acid Conformation
D006601:Hexoses; D004247:DNA