Cell transplantation inhibits inflammatory reaction and stimulates repair processes in burn wound.
We compared the effects of transplantation of fetal fibroblasts and fibroblast-like mesenchymal stem cells of the bone marrow on healing of deep burn wound in rats. It was found that transplantation of fetal fibroblasts and fibroblast-like mesenchymal stem cells on the burn surface reduces cell infiltration, promotes the formation of vessels and granulation tissue, which creates conditions for more rapid healing of the burn wounds.
Rasulov
M F
MF
Institute of Transplantology and Artificial Organs. krashen@rambler.ru
Vasilenko
V T
VT
Zaidenov
V A
VA
Onishchenko
N A
NA
D000818:Animals; D001706:Biopsy; D002056:Burns / Q000473:pathology* / Q000628:therapy*; D005347:Fibroblasts / Q000637:transplantation; D006652:Histological Techniques; D007249:Inflammation / Q000517:prevention & control*; D008297:Male; D045164:Mesenchymal Stem Cell Transplantation; D051381:Rats; D017208:Rats, Wistar; D014945:Wound Healing / Q000502:physiology*