Total-body irradiation of canine lymphoma.
In the continuing search for models which are potentially useful for experimental therapeutics and other radiobiological studies, spontaneous lymphoma in canines has been virtually ignored. These neoplasms closely resemble their histologic counterpart in humans with respect to anatomic sites of involvement and other features. We have examined the responsiveness of canine lymphoma to total-body irradiation, and objective remissions of disease have been observed.
Johnson
R E
RE
Radiation Branch, Cancer Chemotherapy National Service Center, and Viral Oncology Branch, National Cancer Institute, Bethesda, Maryland, USA.
Cameron
T P
TP
Kinard
R
R
D000818:Animals; D004195:Disease Models, Animal; D004285:Dogs; D005260:Female; D008223:Lymphoma / Q000175:diagnosis* / Q000532:radiotherapy*; D008297:Male; D016896:Treatment Outcome; D014916:Whole-Body Irradiation / Q000009:adverse effects / Q000379:methods*