Photochromically-controlled, reversibly-activated MRI and optical contrast agent.
The contrast agent which tethers a spiropyran group to a Gd-DO3A moiety has higher relaxivity and fluorescence intensity in the dark; the relaxivity and fluorescence intensity decrease after irradiation with visible light.
Tu
Chuqiao
C
Department of Biomedical Engineering, University of California, Davis, CA 95616, USA.
Louie
Angelique Y
AY
D003287:Contrast Media / Q000138:chemical synthesis / Q000737:chemistry*; D007536:Isomerism; D008279:Magnetic Resonance Imaging; D015394:Molecular Structure; D010777:Photochemistry
D003287:Contrast Media