title: NHC-containing chiral bidentate ligands: synthesis and evaluation in enantioselective copper-catalyzed conjugate addition.
abstract: New chiral phosphine-, thiolate-, mesylate-, and tosylate-containing N-heterocyclic carbene ligands have been synthesized in fair to excellent yield. These bidentate ligands have been evaluated in enantioselective copper-catalyzed conjugate addition to both cyclic and acyclic enones and displayed good catalytic activities and poor to good enantiomeric excesses (up to 80%).
authors: UMR CNRS 6226, Sciences Chimiques de Rennes, Ecole Nationale Supérieure de Chimie de Rennes, Av. du Général Leclerc, 35700 Rennes, France.
authors: Hervé
authors: H
authors: Clavier
authors: Jean-Claude
authors: JC
authors: Guillemin
authors: Marc
authors: M
authors: Mauduit