Preparation of ultrafine particles of azithromycin by sonochemical method.
Sonochemical method was used to prepare ultrafine Azithromycin. The morphology and size distribution of the particles prepared were characterized by scanning electron micrograph (SEM) and Zetasizer Nanoinstrument. The chemical bonding of production was examined by Fourier transform infra-red absorption spectroscopy (FT-IR). The result shows that different diameter particles of Azithromycin were prepared, and no fundamental bonding change in the Azithromycin molecule after preparation.
Pi
Zhen-bang
ZB
Faculty of Material Science and Chemistry Engineering, China University of Geosciences, Wuhan, PR China. xktian@cug.edu.cn <xktian@cug.edu.cn>
Zhao
Xiao-yu
XY
Yang
Chao
C
Fei
Jin-bo
JB
Tian
Xi-ke
XK
D000900:Anti-Bacterial Agents / Q000138:chemical synthesis*; D017963:Azithromycin / Q000138:chemical synthesis*; D000077286:Cetrimonium; D002593:Cetrimonium Compounds; D008855:Microscopy, Electron, Scanning; D053758:Nanoparticles / Q000737:chemistry; D010316:Particle Size; D017550:Spectroscopy, Fourier Transform Infrared; D014465:Ultrasonics
D000900:Anti-Bacterial Agents; D002593:Cetrimonium Compounds; D017963:Azithromycin; D000077286:Cetrimonium