title: Increased B-type natriuretic peptide levels in patients with apical ballooning syndrome - consecutive cases report.
abstract: We investigated B-type natriuretic peptide (BNP) levels in 10 consecutive patients (all women, mean age 60.4+/-7.8 years) with apical ballooning syndrome. Mean baseline plasma BNP level was 272.6+/-170.4 pg/ml and exceeded the normal range in 8 (80%) patients. When normal levels were adjusted for age and gender, all 10 patients had elevated BNP. Two patients with the highest BNP levels (630 and 423 pg/ml) presented with significant hemodynamic compromise. BNP levels correlated negatively with left ventricular ejection fraction. Increase in BNP levels in apical ballooning syndrome may support the neurohormonal etiology in these patients and requires further studies.
authors: Marcin
authors: M
authors: Grabowski
authors: Krzysztof Jerzy
authors: KJ
authors: Filipiak
authors: Lukasz Andrzej
authors: LA
authors: Malek
authors: Radoslaw
authors: R
authors: Piatkowski
authors: Piotr
authors: P
authors: Scislo
authors: Grzegorz
authors: G
authors: Karpinski
authors: Grzegorz
authors: G
authors: Opolski
mesh_terms: D015415:Biomarkers / Q000097:blood; D018450:Disease Progression; D004452:Echocardiography; D004562:Electrocardiography; D005260:Female; D006801:Humans; D008875:Middle Aged; D020097:Natriuretic Peptide, Brain / Q000097:blood*; D011379:Prognosis; D013315:Stress, Psychological / Q000097:blood / Q000150:complications*; D013577:Syndrome; D018487:Ventricular Dysfunction, Left / Q000097:blood* / Q000209:etiology / Q000503:physiopathology
chemical_list: D015415:Biomarkers; D020097:Natriuretic Peptide, Brain