Outcome of infants born to women with chronic kidney disease.
Pregnancy in women with chronic kidney disease is not uncommon and is not without risk to the mother and child. This article reviews the literature on the outcome of infants from pregnancies in women with chronic kidney disease (CKD), including those receiving dialysis and those living with a functional kidney transplant. Pregnancy in women with CKD and end-stage renal disease (ESRD) is associated with a higher rate of premature birth and small-for-gestational-age (SGA) infants, with resultant increase in neonatal mortality. Although congenital anomalies or long-term developmental issues do not appear to be a significant risk, these areas deserve further study, especially as newer immunosuppressive medications are employed in kidney transplant recipients.
Blowey
Douglas L
DL
Department of Pediatrics, Children's Mercy Hospitals & Clinics, University of Missouri at Kansas City, Kansas City, MO, USA. dblowey@cmh.edu
Warady
Bradley A
BA
D047228:Angiotensin II Type 1 Receptor Blockers / Q000008:administration & dosage / Q000009:adverse effects; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000008:administration & dosage / Q000009:adverse effects; D002657:Child Development; D002908:Chronic Disease; D000013:Congenital Abnormalities / Q000453:epidemiology; D005260:Female; D006801:Humans; D007226:Infant Mortality; D007231:Infant, Newborn; D007674:Kidney Diseases / Q000150:complications* / Q000628:therapy; D016030:Kidney Transplantation; D011247:Pregnancy; D011256:Pregnancy Outcome; D006435:Renal Dialysis
D047228:Angiotensin II Type 1 Receptor Blockers; D000806:Angiotensin-Converting Enzyme Inhibitors