Probing the effects of microwave irradiation on enzyme-catalysed organic transformations: the case of lipase-catalysed transesterification reactions.
The lipase-catalysed transesterification reaction of methyl acetoacetate in toluene as a solvent has been studied using carefully controlled conditions. Results suggest that microwave heating does not have a noticeable effect on reaction rate or product conversion.
Leadbeater
Nicholas E
NE
Department of Chemistry, University of Connecticut, 55 North Eagleville Road, Storrs, CT 06269-3060, USA. nicholas.leadbeater@uconn.edu
Stencel
Lauren M
LM
Wood
Eric C
EC
D000090:Acetoacetates / Q000737:chemistry* / Q000528:radiation effects; D000438:Alcohols / Q000737:chemistry* / Q000528:radiation effects; D002175:Candida / Q000201:enzymology; D002384:Catalysis / Q000528:radiation effects; D008049:Lipase / Q000737:chemistry* / Q000528:radiation effects; D008872:Microwaves; D012997:Solvents / Q000737:chemistry; D013696:Temperature; D013997:Time Factors
D000090:Acetoacetates; D000438:Alcohols; D012997:Solvents; C005217:methyl acetoacetate; D008049:Lipase