Prenatal diagnosis of persistent right umbilical vein using three-dimensional sonography with power Doppler.
OBJECTIVE
To investigate the incidence and the importance of isolated persistent right umbilical vein (PRUV) in our obstetric population and to determine the role of three-dimensional (3D) ultrasound in prenatal diagnosis of isolated PRUV.


METHODS
A total of 1,302 women who received regular antenatal care by a sole obstetrician at our hospital were prospectively evaluated between July 2003 and April 2005. Detailed anatomical evaluation of the fetus was performed by one sonographer. When the diagnosis of PRUV was made, it was confirmed by a senior obstetrician. 3D ultrasound with power Doppler was applied to delineate local anatomy. Echocardiography was performed in all the newborns by pediatric cardiologists to confirm the prenatal diagnosis and to evaluate for the presence of associated anomalies.


RESULTS
Six fetuses with PRUV were detected among the 1,302 study subjects. The incidence of PRUV in our population was 0.46% (1:217 live births). Vascular anatomy was easy to demonstrate using 3D power Doppler. The ductus venous (DV) was present in all six fetuses. An atrial septal defect was shown to exist in four newborns by neonatal echocardiography, but spontaneous closure had occurred in the follow-up scan.


CONCLUSIONS
PRUV is a common vascular anomaly that is easy to be overlooked. Reconstruction of the portal system in the affected fetuses using 3D ultrasound facilitated the identification of the DV. If the DV is present, and other anomalies are excluded, the fetus with PRUV has a good outcome.
Yang
Pei-Yin
PY
Department of Obstetrics and Gynecology, Changhua Christian Hospital, Changhua, Taiwan.
Wu
Joung-Liang
JL
Yeh
Guang-Perng
GP
Chou
Pan-Hsin
PH
Hsu
Jui-Chang
JC
Hsieh
Charles Tsung-Che
CT
D000328:Adult; D018376:Cardiovascular Abnormalities / Q000000981:diagnostic imaging* / Q000453:epidemiology; D005260:Female; D005865:Gestational Age; D006801:Humans; D021621:Imaging, Three-Dimensional / Q000379:methods; D015994:Incidence; D008423:Maternal Age; D011247:Pregnancy; D011446:Prospective Studies; D013624:Taiwan / Q000453:epidemiology; D018615:Ultrasonography, Doppler, Color / Q000379:methods; D016216:Ultrasonography, Prenatal / Q000295:instrumentation / Q000379:methods*; D014471:Umbilical Veins / Q000002:abnormalities* / Q000000981:diagnostic imaging*