Stevens-Johnson syndrome induced by doxycycline.
Stevens-Johnson syndrome (SJS) is an acute mucocutaneous eruption nosologically related to erythema multiforme (EM) and toxic epidermal necrolysis (TEN). Medications are the most common triggering factors for SJS, with anticonvulsants, sulfonamides, penicillins, allopurinol, and nonsteroidal anti-inflammatory drugs (NSAIDs) most commonly implicated. SJS is very rarely associated with tetracyclines. We report a case of doxycycline-induced SJS in a 46-year-old man.
Cac
Natalie N
NN
Department of Dermatology, University of Iowa, Iowa City, USA.
Messingham
Michael J
MJ
Sniezek
Patrick J
PJ
Walling
Hobart W
HW
D004318:Doxycycline / Q000009:adverse effects*; D006801:Humans; D007239:Infections / Q000188:drug therapy; D008297:Male; D008875:Middle Aged; D013262:Stevens-Johnson Syndrome / Q000139:chemically induced* / Q000473:pathology; D014076:Tooth Diseases / Q000188:drug therapy
D004318:Doxycycline