title: Acute postoperative endophthalmitis caused by Staphylococcus lugdunensis.
abstract: Acute postoperative endophthalmitis caused by Staphylococcus lugdunensis is infrequently reported in clinical studies. Five cases of acute postcataract surgery endophthalmitis caused by S. lugdunensis were taken from a multicenter prospective study conducted in four university-affiliated hospitals in France (2004 to 2005). These cases were characterized by severe ocular inflammation occurring with a mean delay of 7.6 days after cataract surgery, severe visual loss (hand motions or less in three cases), and dense infiltration of the vitreous. Each of these patients was initially treated by using a standard protocol with intravitreal (vancomycin and ceftazidime), systemic, and topical antibiotics. Given the severity of the endophthalmitis, even though bacteria were sensitive to intravitreal antibiotics, pars plana vitrectomy was needed in four cases. The final visual prognosis was complicated by severe retinal detachment in three cases. The microbiological diagnosis was reached by using conventional cultures with specific biochemical tests and eubacterial PCR amplification followed by direct sequencing.
authors: Department of Ophthalmology, CHU de Grenoble, Faculté de Médecine, Université Joseph Fourier, Grenoble, France. cchiquet@chu-grenoble.fr
authors: C
authors: C
authors: Chiquet
authors: A
authors: A
authors: Pechinot
authors: C
authors: C
authors: Creuzot-Garcher
authors: Y
authors: Y
authors: Benito
authors: J
authors: J
authors: Croize
authors: S
authors: S
authors: Boisset
authors: J P
authors: JP
authors: Romanet
authors: G
authors: G
authors: Lina
authors: F
authors: F
authors: Vandenesch
mesh_terms: D000208:Acute Disease; D000368:Aged; D000369:Aged, 80 and over; D002387:Cataract Extraction / Q000009:adverse effects*; D003470:Culture Media; D009877:Endophthalmitis / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology; D015818:Eye Infections, Bacterial / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology; D005260:Female; D005602:France; D006785:Hospitals, University; D006801:Humans; D008297:Male; D008875:Middle Aged; D016133:Polymerase Chain Reaction / Q000379:methods*; D011183:Postoperative Complications; D013203:Staphylococcal Infections / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology; D013210:Staphylococcus / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*
chemical_list: D003470:Culture Media