title: Serum ghrelin changes in thyroid dysfunction.
abstract: BACKGROUND
  Thyroid dysfunction is associated with changes in the appetite. Ghrelin can regulate feeding behavior. The aim of this study was to evaluate whether ghrelin plays a role in the appetite changes in different states of thyroid dysfunction.
  
  
  METHODS
  The serum ghrelin levels were measured in 45 newly diagnosed hyperthyroid and 45 newly diagnosed hypothyroid patients before and after medical treatment. Forty-five healthy subjects were also studied as control group.
  
  
  RESULTS
  The ghrelin levels did not change significantly in patients with hyperthyroidism or hypothyroidism before and after the treatment. The ghrelin levels were not different from those of the control group.
  
  
  CONCLUSIONS
  Ghrelin is not likely to be the primary determinant of appetite changes in thyroid dysfunction.
authors: Endocrinology and Metabolism Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
authors: Abdolsamad
authors: A
authors: Sadegholvad
authors: Mojhgan
authors: M
authors: Afkhamizadeh
authors: Gholamhossein
authors: G
authors: Ranjbar-Omrani
mesh_terms: D000328:Adult; D001066:Appetite / Q000502:physiology*; D015992:Body Mass Index; D005260:Female; D054439:Ghrelin; D006801:Humans; D006980:Hyperthyroidism / Q000097:blood*; D007037:Hypothyroidism / Q000097:blood*; D015592:Immunoradiometric Assay; D008297:Male; D008875:Middle Aged; D036361:Peptide Hormones / Q000097:blood*; D011863:Radioimmunoassay; D013963:Thyroid Hormones / Q000097:blood
chemical_list: D054439:Ghrelin; D036361:Peptide Hormones; D013963:Thyroid Hormones