Constituents of Gardenia volkensii: their brine shrimp lethality and DPPH radical scavenging properties.
The seeds and the pulp of Gardenia volkensii yielded one new iridiod, namely 4-(2N-gardenamide)n-butanoic acid, together with the known iridoids genipin and genipin gentiobioside, the pterocarpin medicarpin, coumarins, phenylpropanoids, benzenoids and triterpenes. The structures of these were determined on the basis of spectroscopic data and by comparison of obtained data with those from literature. The fruit extracts of this plant exhibited moderate radical scavenging activity against DPPH radical and moderate lethality against brine shrimps (Artemia salina).
Juma
Bernard F
BF
Department of Chemistry, University of Botswana, Private Bag UB 00704, Gaborone, Botswana.
Majinda
Runner R T
RR
D000818:Animals; D001156:Artemia / Q000187:drug effects; D001713:Biphenyl Compounds / Q000737:chemistry* / Q000494:pharmacology; D002087:Butyrates / Q000737:chemistry* / Q000494:pharmacology; D020148:Butyric Acid / Q000737:chemistry; D002855:Chromatography, Thin Layer; D004305:Dose-Response Relationship, Drug; D016166:Free Radical Scavengers / Q000737:chemistry / Q000494:pharmacology; D032062:Gardenia / Q000737:chemistry*; D006834:Hydrazines / Q000737:chemistry* / Q000494:pharmacology; D057889:Iridoid Glycosides; D039823:Iridoids / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D010851:Picrates; D010936:Plant Extracts / Q000737:chemistry* / Q000494:pharmacology; D011728:Pyridones / Q000737:chemistry* / Q000494:pharmacology; D012639:Seeds / Q000737:chemistry
C520435:4-(2N-gardenamide)-n-butanoic acid; D001713:Biphenyl Compounds; D002087:Butyrates; D016166:Free Radical Scavengers; D006834:Hydrazines; D057889:Iridoid Glycosides; D039823:Iridoids; D010851:Picrates; D010936:Plant Extracts; D011728:Pyridones; D020148:Butyric Acid; C007834:genipin; C004931:1,1-diphenyl-2-picrylhydrazyl