Synthesis of multiply substituted alkylidene silacyclohexadiene derivatives via palladium-catalyzed insertion of alkynes into alkylidene silacyclobutenes.
Palladium-catalyzed insertion of activated alkynes into silacyclobutene derivatives proceeded smoothly to afford exo-alkylidenesilacyclohexadiene derivatives of unique structure with diversified conjugation systems in high isolated yields. Interesting regioselectivity of insertion, which afforded only one regioisomer or a mixture of two or more regioisomers, was also observed.
Liu
Junhui
J
Beijing National Laboratory for Molecular Sciences (BNLMS), Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, College of Chemistry, Peking University, Beijing 100871, China.
Sun
Xiaohua
X
Miyazaki
Mikihiro
M
Liu
Lantao
L
Wang
Congyang
C
Xi
Zhenfeng
Z
D000475:Alkenes / Q000138:chemical synthesis* / Q000737:chemistry; D000480:Alkynes / Q000737:chemistry*; D002384:Catalysis; D003500:Cyclization; D053138:Cyclohexenes / Q000737:chemistry*; D015394:Molecular Structure; D010165:Palladium / Q000737:chemistry*; D013237:Stereoisomerism
D000475:Alkenes; D000480:Alkynes; D053138:Cyclohexenes; C048401:1,4-cyclohexadiene; D010165:Palladium