title: [Adverse events relating to antiretroviral prophylaxis for occupational accidents].
abstract: The objective of the study was to describe adverse events detected clinically or in the laboratory that were secondary to the use of antiretroviral agents among individuals undergoing antiretroviral prophylaxis. Evaluations were performed on 37 teaching hospital employees who underwent prophylaxis using four regimens of antiretroviral medication following occupational exposition to contaminated fluids from patients with human immunodeficiency virus infection. Thirty-two (86.5%) developed adverse events detected clinically or in the laboratory. The prophylaxis administered to two professionals (5.4%) had to be suspended because of the reactions that occurred. Adverse events relating to prophylaxis for HIV infection in health care workers who were victims of occupational accidents were frequent. However, it was rarely necessary to withdraw the antiretroviral medication.
authors: Disciplina de Doenças Infecciosas e Parasitárias, Hospital São Paulo, Universidade Federal de São Paulo, 04007-040 São Paulo, SP, Brazil. edubala@netpoint.com.br
authors: Eduardo Alexandrino Servolo
authors: EA
authors: Medeiros
authors: Elcio
authors: E
authors: Bakowski
authors: Silvia Janice Gomes
authors: SJ
authors: Sassi
authors: Alessandra Santana
authors: AS
authors: Destra
mesh_terms: D019380:Anti-HIV Agents / Q000008:administration & dosage / Q000009:adverse effects*; D015658:HIV Infections / Q000517:prevention & control* / Q000635:transmission; D006801:Humans; D017758:Infectious Disease Transmission, Patient-to-Professional / Q000517:prevention & control*; D009784:Occupational Diseases / Q000517:prevention & control*; D010564:Personnel, Hospital
chemical_list: D019380:Anti-HIV Agents