title: The 15-Country Collaborative Study of Cancer Risk among Radiation Workers in the Nuclear Industry: study of errors in dosimetry.
abstract: To provide direct estimates of cancer risk after low-dose protracted exposure to ionizing radiation, a large-scale epidemiological study of nuclear industry workers was conducted in 15 countries. As part of this study, identification and quantification of errors in historical recorded doses was conducted based on a review of dosimetric practices and technologies in participating facilities. The main sources of errors on doses from "high-energy" photons (100-3000 keV) were identified as the response of dosimeters in workplace exposure conditions and historical calibration practices. Errors related to dosimetry technology and radiation fields were quantified to derive period- and facility-specific estimates of bias and uncertainties in recorded doses. This was based on (1) an evaluation of predominant workplace radiation from measurement studies and dosimetry expert assessment and (2) an estimation of the energy and geometry response of dosimeters used historically in study facilities. Coefficients were derived to convert recorded doses to H(p) (10) and organ dose, taking into account different aspects of the calibration procedures. A parametric, lognormal error structure model was developed to describe errors in doses as a function of facility and time period. Doses from other radiation types, particularly neutrons and radionuclide intake, could not be adequately reconstructed in the framework of the 15-Country Study. Workers with substantial doses from these radiation types were therefore identified and excluded from analyses. Doses from "lower-energy" photons (<100 keV) and from "higher-energy" photons (>3 MeV) were estimated to be small.
authors: International Agency for Research on Cancer, Lyon, France.
authors: I
authors: I
authors: Thierry-Chef
authors: M
authors: M
authors: Marshall
authors: J J
authors: JJ
authors: Fix
authors: F
authors: F
authors: Bermann
authors: E S
authors: ES
authors: Gilbert
authors: C
authors: C
authors: Hacker
authors: B
authors: B
authors: Heinmiller
authors: W
authors: W
authors: Murray
authors: M S
authors: MS
authors: Pearce
authors: D
authors: D
authors: Utterback
authors: K
authors: K
authors: Bernar
authors: P
authors: P
authors: Deboodt
authors: M
authors: M
authors: Eklof
authors: B
authors: B
authors: Griciene
authors: K
authors: K
authors: Holan
authors: H
authors: H
authors: Hyvonen
authors: A
authors: A
authors: Kerekes
authors: M-C
authors: MC
authors: Lee
authors: M
authors: M
authors: Moser
authors: F
authors: F
authors: Pernicka
authors: E
authors: E
authors: Cardis
mesh_terms: D000328:Adult; D001822:Body Burden; D015331:Cohort Studies; D004651:Employment / Q000706:statistics & numerical data; D005260:Female; D006801:Humans; D007221:Industry / Q000706:statistics & numerical data; D007391:International Cooperation; D008297:Male; D009381:Neoplasms, Radiation-Induced / Q000401:mortality*; D009688:Nuclear Reactors / Q000706:statistics & numerical data*; D009784:Occupational Diseases / Q000401:mortality*; D016273:Occupational Exposure / Q000032:analysis / Q000706:statistics & numerical data*; D011829:Radiation Dosage; D011834:Radiation Monitoring / Q000706:statistics & numerical data*; D015203:Reproducibility of Results; D018570:Risk Assessment / Q000379:methods*; D012307:Risk Factors; D012680:Sensitivity and Specificity; D016019:Survival Analysis; D015996:Survival Rate; D014915:Whole-Body Counting / Q000706:statistics & numerical data*