Two-dimensional spectroscopy with parallel acquisition of 1H-X and 19F-X correlations.
Two-dimensional NMR spectra correlating both (1)H and (19)F nuclei with either (13)C or (15)N, are recorded at the same time, using a 600-MHz broadband radio frequency probe feeding independent (1)H and (19)F receiver channels. This technique, known as parallel acquisition NMR spectroscopy (PANSY), speeds up multidimensional NMR and is compatible with other fast-acquisition schemes. The method is illustrated with single-bond (HSQC) and multiple-bond (HMBC) experiments on 2-bromophenyl-3-trifluoromethyl-5-methylpyrazole, giving simultaneous (1)H-X and (19)F-X correlation spectra (X = (13) C or (15)N).
Kupce
Eriks
E
Varian Ltd., 6 Mead Road, Yarnton, Oxford, UK.
Cheatham
Steve
S
Freeman
Ray
R
D002247:Carbon Isotopes; D005461:Fluorine; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D015394:Molecular Structure; D009587:Nitrogen Isotopes; D011522:Protons; D011720:Pyrazoles / Q000737:chemistry*; D013997:Time Factors
C521451:2-bromophenyl-3-trifluoromethyl-5-methylpyrazole; D002247:Carbon Isotopes; D009587:Nitrogen Isotopes; D011522:Protons; D011720:Pyrazoles; D005461:Fluorine