[Structural-functional manifestations of cerebrovascular pathology in patients with essential hypertension].
OBJECTIVE
To study functional activity of the brain in hypertensive patients by computer EEG and topographic mapping versus MR-tomography of the brain.


METHODS
Computed EEG and MR-tomography (MRT) of the brain were made in 162 patients (age 28-56, mean age 43 +/- 2.4 years) with essential hypertension (EH) stage II.


RESULTS
Four types of maps reflecting stages of forming defects of electric activity of the brain in patients with hypertension without neurological deficiency were identified. There is evidence about correlation between spectral rhythm power of EEG and severity of structural changes of the brain in hypertensive patients.


CONCLUSIONS
Progression of vascular hypertensive encephalopathy by MRT in hypertensive patients is accompanied with changes in EEG rhythm power: alpha-rhythm index reduction, leveling of its interhemispheric differences, a rise of the low activity index in all the cerebral regions. The latter and alpha-rhythm index reduction may be regarded as markers of cerebral structural changes, primarily, disordered liquorodynamics and periventricular leukoaraiosis in relevant brain regions.
Semke
G V
GV
Mordovin
V F
VF
D000328:Adult; D001921:Brain / Q000473:pathology* / Q000503:physiopathology*; D001931:Brain Mapping / Q000379:methods*; D002561:Cerebrovascular Disorders / Q000209:etiology / Q000473:pathology / Q000503:physiopathology; D018450:Disease Progression; D004569:Electroencephalography / Q000379:methods*; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications* / Q000473:pathology / Q000503:physiopathology; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012720:Severity of Illness Index