Vertebrate gastrulation: the BMP sticker shock.
BMPs are essential regulators of cell fate during early embryonic development. Molecular genetics and in vivo imaging of cell behaviors in zebrafish now demonstrate a role for BMPs in the control of cell adhesion. The work reveals an important new mechanism governing cell movements during gastrulation.
Wallingford
John B
JB
Department of Molecular Cell and Developmental Biology and Institute for Cellular and Molecular Biology, University of Texas, Austin, Texas 78712, USA. wallingford@mail.utexas.edu <wallingford@mail.utexas.edu>
Harland
Richard M
RM
D000818:Animals; D019485:Bone Morphogenetic Proteins / Q000235:genetics / Q000378:metabolism / Q000502:physiology*; D002454:Cell Differentiation; D002465:Cell Movement; D005775:Gastrula / Q000166:cytology / Q000378:metabolism / Q000502:physiology*; D008954:Models, Biological; D014981:Xenopus; D015027:Zebrafish / Q000196:embryology* / Q000235:genetics / Q000378:metabolism
D019485:Bone Morphogenetic Proteins