Chromophobe renal cell carcinoma in a child: case report and review of the literature.
Renal cell carcinomas are rare in children but are in the differential diagnosis of renal masses in children age 5 years and older. We present a case of a chromophobe renal cell carcinoma in an 8-year-old boy that arose as a 7-cm (greatest dimension) unilateral renal mass. The tumor had eosinophilic cells, with the typical perinuclear halos and positive staining with Hale's colloidal iron that are seen in this tumor. Although papillary renal cell carcinomas are the most common variant of renal cell carcinoma in children, chromophobe renal cell carcinoma is a rarely reported variant that is not uncommon and has a relatively favorable prognosis in adults.
Katzman
Philip J
PJ
Department of Pathology and Laboratory Medicine, University of Rochester Medical Center, Rochester, NY, USA. philip_katzman@urmc.rochester.edu
Schwartz
Jeremy I
JI
D002292:Carcinoma, Renal Cell / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D002648:Child; D003937:Diagnosis, Differential; D005500:Follow-Up Studies; D006651:Histocytochemistry; D006801:Humans; D007680:Kidney Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D008297:Male; D009367:Neoplasm Staging; D013997:Time Factors; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D009396:Wilms Tumor / Q000175:diagnosis