title: Melanotic neuroectodermal tumor of infancy: report of a case with myogenic differentiation.
abstract: An 8-month-old boy presented with a 6-week history of a skull mass of the anterior fontanelle. The mass was excised, and the histopathologic features were diagnostic for melanotic neuroectodermal tumor of infancy. The tumor showed focal myogenin positivity, which has not been previously reported in this tumor. The patient has no evidence of recurrent tumor 10 months after the excision. No adjuvant therapy was given. In addition, we stained a case of melanotic neuroectodermal tumor of infancy obtained from Columbus Children's Hospital; focal myogenin positivity was present.
authors: Department of Pathology, Arkansas Children's Hospital and University of Arkansas for Medical Sciences, Little Rock, AR, USA. ellisondalea@uams.edu
authors: Dale A
authors: DA
authors: Ellison
authors: Badih
authors: B
authors: Adada
authors: Stephen J
authors: SJ
authors: Qualman
authors: David M
authors: DM
authors: Parham
mesh_terms: D000951:Antigens, Neoplasm; D005500:Follow-Up Studies; D006801:Humans; D007150:Immunohistochemistry; D007223:Infant; D007633:Keratins / Q000378:metabolism; D008297:Male; D058950:Melanoma-Specific Antigens; D018008:Myogenin / Q000378:metabolism*; D009363:Neoplasm Proteins / Q000378:metabolism; D017600:Neuroectodermal Tumor, Melanotic / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000378:metabolism / Q000473:pathology / Q000601:surgery; D010751:Phosphopyruvate Hydratase / Q000378:metabolism; D011859:Radiography; D012888:Skull Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000378:metabolism / Q000473:pathology / Q000601:surgery; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D000951:Antigens, Neoplasm; D058950:Melanoma-Specific Antigens; D018008:Myogenin; D009363:Neoplasm Proteins; D007633:Keratins; D010751:Phosphopyruvate Hydratase