title: [A case of tuberculous aneurysm of subclavian artery occurred in the course of treatment for miliary tuberculosis].
abstract: This case is a 56-year old woman. Steroids were being administered perorally after a thymectomy for myasthenia gravis. A fever of 38-39 degrees Celsius appeared during night, an abnormal shadow showed up on a chest X-ray and the patient was hospitalized. Gaffky No. 2 acid-fast bacilli were detected in the patient's sputum and the chest CT showed diffuse granular-like shadow, the patient was diagnosed as miliary tuberculosis and treatment with combined use of INH, RFP, EB, and PZA was started. Subsequently, fever started to subside and the miliary shadow on chest X-ray improved, however, six weeks after the start of treatment, hoarseness and dysphagia appeared. From the cervical CT and cervical angiography findings, the diagnosis of right subclavian artery impending ruptured aneurysm was made. Because the patient's sputum was acid-fast bacilli positive and because the patient had undergone thymectomy, it was decided that it would be difficult to treat her by a thoracotomy again. Therefore, a right subclavian artery stent insertion, right subclavian artery-right common carotid artery bypass creation operation was carried out with the objective of blocking the flow of blood to the aneurysm. The hoarseness and dysphagia improved post-operatively and the patient's progress is being monitored. Tuberculous aneurysms are a rare affection and they are mostly discovered when the autopsy is done, however, this case was diagnosed due to the manifestation of subjective symptoms. While this case was not diagnosed histopathologically, it is envisaged from the clinical progress that this was a tuberculous subclavian aneurysm complicated during the treatment for miliary tuberculosis.
authors: Department of First Internal Medicine, Hakujikai Memorial Hospital, 5-11-1 Shikahama, Adachi-ku, Tokyo 123-0864 Japan. projectk@nms.ac.jp
authors: Keitaro
authors: K
authors: Sakakibara
authors: Tetsuya
authors: T
authors: Okano
authors: Shuji
authors: S
authors: Kurane
authors: Shouji
authors: S
authors: Kudoh
mesh_terms: D000785:Aneurysm, Infected / Q000150:complications*; D005260:Female; D006801:Humans; D008875:Middle Aged; D013348:Subclavian Artery; D014376:Tuberculosis / Q000150:complications*; D014391:Tuberculosis, Miliary / Q000150:complications / Q000188:drug therapy*