title: Evaluation of vascular infiltration in resected patients for pancreatic cancer: comparison among multidetector CT, intraoperative findings and histopathology.
abstract: BACKGROUND
  To assess vascular infiltration is crucial in surgical planning of pancreatic cancer. Our aim was to assess the capability of multidetector CT in detecting vascular infiltration.
  
  
  METHODS
  We evaluated 37 patients with pancreatic tumors. The relation between tumor and vessels was classified: grade 0: no contact between lesion and vessel; grade I: focal contiguity without modification of the vessel caliber; grade II: lesion surrounding the vessel, without reduction of its lumen; grade III: cancer surrounding the vessel with reduction or obstruction of its lumen. CT grades were compared to intraoperative findings and histopathology.
  
  
  RESULTS
  We evaluated 52 critical vessels with the following CT grades: grade 0 (4 cases), grade I (13 cases), grade II (17 cases), grade III (18 cases). Vascular resection was performed in 26 patients, with a total of 31 resected vessels (3 of grade 0, 5 of grade I, 8 of grade II, 15 of grade III). Histopathology excluded vascular infiltration in 4/4 cases with grade 0 and in 10/13 cases with grade I and confirmed it in 14/17 cases with grade II and 14/18 cases with grade III.
  
  
  CONCLUSIONS
  Multidetector CT is accurate in detecting vascular involvement and provides pre-operative information to effectively plan resection.
authors: Diagnostic and Interventional Radiology, Department of Oncology, Transplants and Advanced Technologies in Medicine, University of Pisa, Pisa, Italy. smazzeo@med.unipi.it
authors: Salvatore
authors: S
authors: Mazzeo
authors: Carla
authors: C
authors: Cappelli
authors: Davide
authors: D
authors: Caramella
authors: Marco
authors: M
authors: Del Chiaro
authors: Daniela
authors: D
authors: Campani
authors: Luca
authors: L
authors: Pollina
authors: Gabriele
authors: G
authors: Caproni
authors: Valentina
authors: V
authors: Battaglia
authors: Annalisa
authors: A
authors: Belcari
authors: Niccola
authors: N
authors: Funel
authors: Giulio
authors: G
authors: Di Candio
authors: Federica
authors: F
authors: Forasassi
authors: Ugo
authors: U
authors: Boggi
authors: Generoso
authors: G
authors: Bevilacqua
authors: Franco
authors: F
authors: Mosca
authors: Carlo
authors: C
authors: Bartolozzi
mesh_terms: D000368:Aged; D001706:Biopsy; D003287:Contrast Media; D005260:Female; D006801:Humans; D007479:Iopamidol / Q000031:analogs & derivatives; D008297:Male; D060787:Neoplasm Grading; D009389:Neovascularization, Pathologic / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D010180:Pancreatectomy / Q000379:methods; D010190:Pancreatic Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D014057:Tomography, X-Ray Computed / Q000379:methods*
chemical_list: D003287:Contrast Media; C057937:iomeprol; D007479:Iopamidol