Modeling immune behavior for experimentalists.
This article outlines the requirements for useful models of biologic systems. Such models should fulfill three conditions: (i) suit the bottom-up data of the living system, not merely adhere to top-down logic; (ii) abet experimentation by stimulating new ideas for novel experiments; and (iii) engage the mind of the experimentalist with understandable, visual representations. Seven characteristics of a useful model are discussed.
Cohen
Irun R
IR
Department of Immunology, Weizmann Institute of Science, Rehovot, Israel. irun.cohen@weizmann.ac.il
D000818:Animals; D006801:Humans; D017056:Medical Laboratory Personnel; D018448:Models, Immunological; D012107:Research Design / Q000592:standards*