title: The effects of fenvalerate on different tissues of freshwater fish Cirrhinus mrigala.
abstract: The histopathological changes of fenvalerate on the gill, kidney, liver and intestine tissues of the Cirrhinus mrigala were determined by light microscopy. The fish were exposed to two sub-lethal concentrations of fenvalerate (1.5-3.0 ppb). The most common gill changes at all concentrations of fenvalerate were epithelial hyperplasia, epithelial necrosis, desquamation and lamellar fusion. Besides, epithelial lifting, oedema, swelling at the tips of secondary lamellae and curling of secondary lamellae were other histopathological changes. Necrosis of tubular epithelium, pycnotic nuclei in the hematopoietic tissue, hypertrophied epithelial cells of renal tubules, narrowing of the tubular lumen, expansion of space inside the Bowman's capsule and contraction of the glomerulus were observed in kidney tissues of fish. Hepatic lesions in the liver tissues of fish exposed to fenvalerate were characterized by congestion, cloudy swelling of hepatocytes and focal necrosis. Atrophy of epithelial cells, necrosis of epithelial cells, desquamation of mucosal epithelium and infiltration of lymphocytes into the lamina propria were detected in intestine tissues of fish after exposure to fenvalerate.
authors: Environmental Science and Biotechnology Research Unit, Department of Zoology, Loyola College, Tamil Nadu, India.
authors: Babu
authors: B
authors: Velmurugan
authors: Mariadoss
authors: M
authors: Selvanayagam
authors: Elif I
authors: EI
authors: Cengiz
authors: Erhan
authors: E
authors: Unlu
mesh_terms: D000818:Animals; D016022:Case-Control Studies; D003530:Cyprinidae; D004305:Dose-Response Relationship, Drug; D004781:Environmental Exposure / Q000009:adverse effects*; D005618:Fresh Water; D005880:Gills / Q000187:drug effects / Q000473:pathology; D007150:Immunohistochemistry / Q000662:veterinary; D007306:Insecticides / Q000633:toxicity*; D007422:Intestines / Q000187:drug effects / Q000473:pathology; D007668:Kidney / Q000187:drug effects / Q000473:pathology; D008099:Liver / Q000187:drug effects / Q000473:pathology; D009570:Nitriles / Q000633:toxicity*; D011722:Pyrethrins / Q000633:toxicity*; D013997:Time Factors; D014874:Water Pollutants, Chemical / Q000633:toxicity*
chemical_list: D007306:Insecticides; D009570:Nitriles; D011722:Pyrethrins; D014874:Water Pollutants, Chemical; C017690:fenvalerate