Cytocompatibility and electrochemical properties of Ti-Au alloys for biomedical applications.
The purpose of this study was to develop Ti-Au alloys with a higher resistant to corrosion, better biocompatibility, and better mechanical properties than the commercially pure titanium and its alloys. Ti-Au alloys were designed with a gold content that ranged from 0 to 5.0 at % in steps of 1.0 at %. Properties of the alloys including chemical composition, microstructure, phase, hardness, electrochemical properties, and the cytotoxicity were investigated. Only the alpha phase existed in the Ti-Au alloys. The addition of gold to the titanium decreased the alpha to beta transformation temperature. The acicular alpha phase became thinner and the hardness value increased with increasing gold content. In the electrochemical tests, Ti-Au alloys had a higher resistant to corrosion than had pure titanium and did not exhibit pitting corrosion in artificial saliva. The cytotoxicities of the Ti-Au alloys were similar to that of pure titanium. Therefore, Ti-Au alloys could be used as biomaterials in the medical and dental fields.
Oh
Keun-Taek
KT
Research Institute of Dental Biomaterials and Bioengineering, College of Dentistry, Yonsei University, Seoul, South Korea.
Kang
Dong-Kuk
DK
Choi
Good-Sun
GS
Kim
Kyoung-Nam
KN
D000497:Alloys / Q000737:chemistry* / Q000633:toxicity; D000818:Animals; D001672:Biocompatible Materials / Q000737:chemistry* / Q000633:toxicity; D003343:Corrosion; D004563:Electrochemistry; D005347:Fibroblasts / Q000187:drug effects; D006047:Gold Alloys / Q000737:chemistry* / Q000633:toxicity; D006244:Hardness; D008422:Materials Testing; D051379:Mice; D014025:Titanium / Q000737:chemistry* / Q000633:toxicity
D000497:Alloys; D001672:Biocompatible Materials; D006047:Gold Alloys; D014025:Titanium