title: Adherence and retention of female injection drug users in a phase III clinical trial in inner city Baltimore.
abstract: Adherence and retention of female injection drug users (IDUs) in clinical trials are not well known and were evaluated among 458 female IDUs in a clinical trial in Baltimore. Of all, 62.9% were adherent to visits (attended > or = 80% of visits). Of women with > or = 1 visit after enrollment, 76% were adherent to treatment (took > or = 80% of pills); 27.7% were lost to follow-up (missed > or = 3 consecutive visits). Women nonadherent to visits were younger and less likely to be on methadone. Women lost to follow-up were younger, more often white, not on methadone, and injecting drugs daily. Fair-moderate adherence to visits and treatment occurs among female IDUs in a clinical trial.
authors: Johns Hopkins Medical Institutions, Baltimore, Maryland 21205, USA. rdsemba@jhmi.edu
authors: Richard D
authors: RD
authors: Semba
authors: Erin P
authors: EP
authors: Ricketts
authors: Shruti F
authors: SF
authors: Mehta
authors: Gregory D
authors: GD
authors: Kirk
authors: Carl
authors: C
authors: Latkin
authors: Noya
authors: N
authors: Galai
authors: David
authors: D
authors: Vlahov
mesh_terms: D000328:Adult; D015142:Baltimore / Q000453:epidemiology; D003710:Demography; D005260:Female; D005500:Follow-Up Studies; D015658:HIV Infections / Q000453:epidemiology; D006526:Hepatitis C / Q000453:epidemiology; D006801:Humans; D008691:Methadone / Q000627:therapeutic use*; D009294:Narcotics / Q000627:therapeutic use*; D015995:Prevalence; D012153:Retention, Psychology; D015819:Substance Abuse, Intravenous / Q000453:epidemiology* / Q000534:rehabilitation*; D014505:Urban Population / Q000706:statistics & numerical data*
chemical_list: D009294:Narcotics; D008691:Methadone