The diagnosis, staging, and treatment options for mycosis fungoides.
BACKGROUND
Cutaneous T-cell lymphoma (CTCL) represents a spectrum of diseases composed of malignant T lymphocytes. The most common type is mycosis fungoides (MF). An accurate diagnosis of early MF may be difficult because of the varied clinical and histologic expressions of the disease.


METHODS
The authors review the epidemiology, possible risk factors, clinical manifestations, diagnostic techniques, staging, prognosis, and treatment options for MF.


RESULTS
The varied and often nonspecific clinical and histologic presentations of MF may delay diagnosis and staging, thus necessitating further studies such as immunophenotyping and T-cell receptor gene rearrangement analysis.


CONCLUSIONS
A multidisciplinary approach to the diagnosis, staging, and treatment of MF assists in optimizing outcomes from management of patients with this disease.
Keehn
Connie A
CA
Cutaneous Oncology Program, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL 33612, USA.
Belongie
Iriana P
IP
Shistik
Galina
G
Fenske
Neil A
NA
Glass
L Frank
LF
D000970:Antineoplastic Agents / Q000627:therapeutic use; D006801:Humans; D009182:Mycosis Fungoides / Q000175:diagnosis* / Q000453:epidemiology / Q000628:therapy; D009367:Neoplasm Staging; D010789:Phototherapy; D011379:Prognosis; D012307:Risk Factors; D012878:Skin Neoplasms / Q000175:diagnosis* / Q000188:drug therapy
D000970:Antineoplastic Agents