[Diagnosis, management and treatment of chronic Chagas' heart disease in areas where Trypanosoma cruzi infection is not endemic].
Chagas' disease, or American trypanosomiasis, is a parasitic zoonosis found only in the Americas. Under natural conditions, Trypanosoma cruzi is transmitted by insects belonging to different species of Triatoma. However, several routes of transmission that do not involve insect vectors have also been described, such as transmission via blood products or transplantation of infected organs, and vertical transmission. At present, the number of people infected with Chagas' disease worldwide is estimated to be about 10-12 million. The process of urbanization in Latin America and migratory population movements from endemic countries have led to the disease being diagnosed in non-endemic areas. It is estimated that 20-30% of individuals infected with T. cruzi will develop symptomatic heart disease at some point during their lives. The specific differential characteristics of chronic chagasic cardiopathy, lack of knowledge of the disease among many healthcare workers, and the fact that arrhythmia or sudden death is frequently the first manifestation of disease all make it essential that diagnostic and therapeutic protocols for the disease are developed and disseminated. The aim should be to improve patient care by increasing understanding of the condition by physicians and other healthcare professionals who may be involved in its detection and treatment.
Gascón
Joaquim
J
Secció Medicina Tropical-Centre Salut Internacional, IDIBAPS, Hospital Clínic, Barcelona, Spain. jgascon@clinic.ub.es
Albajar
Pedro
P
Cañas
Elías
E
Flores
María
M
Gómez i Prat
Jordi
J
Herrera
Ramón N
RN
Lafuente
Carlos A
CA
Luciardi
Héctor L
HL
Moncayo
Alvaro
A
Molina
Lluís
L
Muñoz
José
J
Puente
Sabino
S
Sanz
Ginés
G
Treviño
Begoña
B
Sergio-Salles
Xavier
X
D000818:Animals; D002598:Chagas Cardiomyopathy / Q000150:complications / Q000175:diagnosis* / Q000628:therapy*; D006801:Humans; D014349:Trypanosoma cruzi