Activity of faropenem against middle ear fluid pathogens from children with acute otitis media in Costa Rica and Israel.
Faropenem was tested against 1,188 middle ear fluid pathogens from children in Israel and Costa Rica. Against Streptococcus pneumoniae and Haemophilus influenzae, faropenem was the most active beta-lactam, with activity that was similar to or greater than of the other oral antimicrobial classes studied. Faropenem was also active against Moraxella catarrhalis and Streptococcus pyogenes.
Stone
Kimberley Clawson
KC
Replidyne Inc., 1450 Infinite Drive, Louisville, CO 80027, USA.
Dagan
Ron
R
Arguedas
Adriano
A
Leibovitz
Eugene
E
Wang
Elaine
E
Echols
Roger M
RM
Janjic
Nebojsa
N
Critchley
Ian A
IA
D000208:Acute Disease; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D002648:Child; D003364:Costa Rica; D004432:Ear, Middle / Q000382:microbiology*; D006193:Haemophilus influenzae / Q000187:drug effects*; D006801:Humans; D007557:Israel; D008826:Microbial Sensitivity Tests / Q000379:methods; D001936:Moraxella catarrhalis / Q000187:drug effects; D010034:Otitis Media with Effusion / Q000382:microbiology*; D013296:Streptococcus pneumoniae / Q000187:drug effects*; D013297:Streptococcus pyogenes / Q000187:drug effects; D047090:beta-Lactams / Q000494:pharmacology*
D000900:Anti-Bacterial Agents; D047090:beta-Lactams; C107057:fropenem