Tetraaddition of PhLi to a ketocalixarene derivative.
[reaction: see text] Reaction of a ketocalixarene with 2.2 equiv or an excess of PhLi affords diaddition and tetraaddition products, respectively. Ionic hydrogenation of the tetraalcohol 8a yields a calix[4]arene monosubstituted by phenyl groups at all four methylene bridges.
Kuno
Lev
L
Department of Organic Chemistry, The Hebrew University of Jerusalem, Jerusalem 91904, Israel.
Seri
Noa
N
Biali
Silvio E
SE