Contribution of procalcitonin to occult bacteraemia detection in children.
We conducted a prospective study in 215 children, 3 to 36 months of age, presenting with fever > or = 39 degrees C without obvious origin, in order to evaluate the diagnostic value of procalcitonin (PCT) in detection of occult bacteraemia. PCT associated with white blood cell count constitutes an efficient screening method with sensitivity 100%, specificity 61.9% and positive and negative likelihoods ratios of 2.62 and 0, respectively.
Guen
Christele Gras-Le
CG
Paediatric Intensive Care Unit, CHU Nantes, Nantes, France. christele.grasleguen@chu-nantes.fr
Delmas
Caroline
C
Launay
Elise
E
Caillon
Jocelyne
J
Loubersac
Virginie
V
Picherot
Georges
G
Roze
J Christophe
JC
D016470:Bacteremia / Q000175:diagnosis* / Q000652:urine*; D015415:Biomarkers; D002116:Calcitonin / Q000652:urine*; D015740:Calcitonin Gene-Related Peptide; D002675:Child, Preschool; D006801:Humans; D007223:Infant; D011498:Protein Precursors / Q000652:urine*
D015415:Biomarkers; C000606589:CALCA protein, human; D011498:Protein Precursors; D002116:Calcitonin; D015740:Calcitonin Gene-Related Peptide