[Long-term efficacy and safety of chondroitin sulphate (structum, France) in patients with coxarthrosis].
OBJECTIVE
To evaluate long-term therapeutic effect and safety of structum in patients with manifest coxarthrosis.


METHODS
Twenty patients with manifest coxarthrosis of degree I-III were given a 6 month structum course. Criteria of efficacy were Leken index, pain in the affected joints, nonsteroid anti-inflammatory drugs requirement, assessment of the efficacy by the patient and the doctor. Structum effects were studied with x-ray examination, CT, INC index. The assessment was made at baseline, after 3 and 6 month therapy and 6.12 and 18 months after the end of the study.


RESULTS
All the patients achieved positive results without side effects on coagulation.


CONCLUSIONS
Structum is highly effective in patients with manifest osteoarthrosis of hip joints. Is modifies symptoms, has a potential chondroprotective effect, long-term aftereffect, no significant negative action of coagulation, is well tolerated.
Shmidt
E I
EI
Bilinskaia
M A
MA
Belozerova
I V
IV
Soldatov
D G
DG
Dmitrieva
M E
ME
D000328:Adult; D000368:Aged; D001777:Blood Coagulation / Q000187:drug effects; D002809:Chondroitin Sulfates / Q000627:therapeutic use*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D015207:Osteoarthritis, Hip / Q000097:blood / Q000000981:diagnostic imaging / Q000188:drug therapy*; D013997:Time Factors; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
D002809:Chondroitin Sulfates