title: Acquisition and diffusion of bla CTX-M-9 gene by R478-IncHI2 derivative plasmids.
abstract: Escherichia coli and Salmonella enterica isolates carrying the bla(CTX-M-9) gene located on plasmids prevailed at the Hospital de la Santa Creu i Sant Pau, Barcelona, Spain in the 1996-1999 period. The bla(CTX-M-9)-carrying plasmids showed a great variability in size, suggesting the mobilization of the gene among different plasmid scaffolds. The aim of the present work was to identify and better characterize the plasmids involved in the spread of the bla(CTX-M-9) gene. Results showed that the majority of these strains carried plasmids belonging to the IncHI2 incompatibility group. The IncHI2 plasmids were further characterized, and found to be related to the reference IncHI2 plasmid R478.
authors: Servei de Microbiologia, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.
authors: Aurora
authors: A
authors: García
authors: Ferran
authors: F
authors: Navarro
authors: Elisenda
authors: E
authors: Miró
authors: Laura
authors: L
authors: Villa
authors: Beatriz
authors: B
authors: Mirelis
authors: Pere
authors: P
authors: Coll
authors: Alessandra
authors: A
authors: Carattoli
mesh_terms: D004926:Escherichia coli / Q000187:drug effects / Q000235:genetics*; D004927:Escherichia coli Infections / Q000382:microbiology*; D029968:Escherichia coli Proteins / Q000235:genetics*; D006761:Hospitals; D006801:Humans; D008969:Molecular Sequence Data; D010957:Plasmids / Q000145:classification / Q000235:genetics*; D011815:R Factors / Q000145:classification / Q000235:genetics*; D012480:Salmonella Infections / Q000382:microbiology*; D019779:Salmonella enterica / Q000187:drug effects / Q000235:genetics*; D013030:Spain; D001618:beta-Lactamases / Q000235:genetics*
chemical_list: D029968:Escherichia coli Proteins; C412613:CTX-M-9 protein, E coli; D001618:beta-Lactamases