The evolving MR imaging appearance of lissencephaly: a case report.
MR imaging of a patient with epilepsy and psychomotor retardation at 5 months revealed parieto-occipital pachygyria with almost normal cortical appearance and thickness in the frontal region; this appearance evolved into diffuse pachygyria at 7 years. The change of the MR imaging findings may have resulted from myelination in the intracortical and subcortical fibers. It is important for clinicians to be aware of the longitudinal changes of the cerebral cortex in lissencephaly.
Takanashi
Jun-ichi
J
Department of Pediatrics, Kameda Medical Center, 929 Higashi-cho, Kamogawa-shi, Chiba 296-8602, Japan. jtaka@kameda.jp
Tada
Hiroko
H
Fujii
Katsunori
K
Barkovich
A James
AJ
D001921:Brain / Q000002:abnormalities* / Q000473:pathology*; D001927:Brain Diseases / Q000151:congenital* / Q000473:pathology*; D002648:Child; D002675:Child, Preschool; D004827:Epilepsy / Q000209:etiology / Q000473:pathology; D005260:Female; D006801:Humans; D007223:Infant; D008279:Magnetic Resonance Imaging; D011596:Psychomotor Disorders / Q000209:etiology / Q000473:pathology