title: [Squamous-cell carcinoma and osteomyelitis: three cases and a review of the literature].
abstract: Chronic osteitis and squamous-cell carcinoma is a rare but classically described association. We report three cases of chronic tibial osteitis which developed open leg trauma. During the surveillance, after a latency period of several years, local signs developed leading to biopsy which provided the diagnosis of degenerative carcinomatosis. Search for locoregional extension or metastatic dissemination was negative. All three patients underwent amputation with good results. This small series, together with a review of the literature, enabled us to describe the principle epidemiological and diagnostic features, focusing on early signs. The appropriate management scheme remains to be determined although amputation, which some may consider as a failure, should not be postponed indefinitely.
authors: Service de Chirurgie Orthopédique et Traumatologique, CHU de Rangueil, 1, avenue Jean-Poulhès, TSA 50032, 31059 Toulouse Cedex 9. jean-michel.laffosse@wanadoo.fr
authors: J-M
authors: JM
authors: Laffosse
authors: H
authors: H
authors: Bensafi
authors: F
authors: F
authors: Accadbled
authors: F
authors: F
authors: Fabié
authors: J-L
authors: JL
authors: Tricoire
authors: J
authors: J
authors: Puget
mesh_terms: D000062:Accidents, Occupational; D000368:Aged; D000671:Amputation, Surgical; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001859:Bone Neoplasms / Q000209:etiology* / Q000473:pathology; D002294:Carcinoma, Squamous Cell / Q000209:etiology* / Q000473:pathology; D002471:Cell Transformation, Neoplastic / Q000473:pathology; D002908:Chronic Disease; D017577:Cutaneous Fistula / Q000209:etiology; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D010019:Osteomyelitis / Q000150:complications*; D013977:Tibia / Q000473:pathology*; D013978:Tibial Fractures / Q000150:complications; D014948:Wounds, Gunshot / Q000150:complications
chemical_list: D000900:Anti-Bacterial Agents