title: Immune changes: 2 h of continuous vs. intermittent cycling.
abstract: Immune changes following 2 h of intensive cycling with or without rest intervals were measured in trained cyclists (n = 12) who functioned as their own controls during two test sessions that were separated by two weeks. Subjects cycled for 2.0 h at approximately 64 % Watts(max) continuously (C) or with 3-min rest intervals (R) interspersed every 10 min (2.6 h total time), with the order of the sessions randomized. Blood samples were collected 30-min pre-exercise, and immediately and 1-h postexercise, and assayed for blood leukocyte subset counts, plasma IL-6, IL-10, IL-1ra, IL-8, PHA-induced lymphocyte proliferation, and natural killer cell activity (NKCA). Significant time effects were measured for all immune measures, but no significant differences in the pattern of change were found between C and R exercise trials. In conclusion, immune changes induced by 2 h of intense and prolonged exercise paralleled those measured when athletes rested 3 min every 10 min of exercise.
authors: Department of HLES, Appalachian State University, Boone, NC, USA. niemandc@appstate.edu
authors: D
authors: D
authors: Nieman
authors: D
authors: D
authors: Henson
authors: G
authors: G
authors: Gojanovich
authors: J M
authors: JM
authors: Davis
authors: C
authors: C
authors: Dumke
authors: A
authors: A
authors: Utter
authors: A
authors: A
authors: Murphy
authors: S
authors: S
authors: Pearce
authors: S
authors: S
authors: McAnulty
authors: L
authors: L
authors: McAnulty
mesh_terms: D000328:Adult; D001642:Bicycling / Q000502:physiology; D016207:Cytokines / Q000097:blood / Q000276:immunology; D005080:Exercise Test / Q000379:methods; D006801:Humans; D007107:Immune System / Q000502:physiology*; D007694:Killer Cells, Natural / Q000276:immunology; D008214:Lymphocytes / Q000097:blood / Q000276:immunology; D008297:Male; D005082:Physical Exertion / Q000502:physiology*; D014481:United States
chemical_list: D016207:Cytokines