title: Small RNAs controlling outer membrane porins.
abstract: Gene regulation by small non-coding RNAs has been recognized as an important post-transcriptional regulatory mechanism for several years. In Gram-negative bacteria such as Escherichia coli and Salmonella, these RNAs control stress response and translation of outer membrane proteins and therefore are key regulators of environmental stress. Recent work has revealed an intimate interplay between small RNA regulation of outer membrane proteins and the stress-induced sigmaE-signalling system, which has an essential role in the maintenance of the integrity of the outer membrane.
authors: Department of Biochemistry and Molecular Biology, University of Southern Denmark, DK-5230 Odense M, Denmark. valentin@bmb.sdu.dk
authors: Poul
authors: P
authors: Valentin-Hansen
authors: Jesper
authors: J
authors: Johansen
authors: Anders A
authors: AA
authors: Rasmussen
mesh_terms: D001426:Bacterial Proteins / Q000235:genetics*; D015964:Gene Expression Regulation, Bacterial; D006090:Gram-Negative Bacteria / Q000378:metabolism*; D018272:Porins / Q000235:genetics*; D012329:RNA, Bacterial / Q000378:metabolism*; D022661:RNA, Untranslated / Q000378:metabolism*; D012808:Sigma Factor / Q000378:metabolism; D014157:Transcription Factors / Q000378:metabolism
chemical_list: D001426:Bacterial Proteins; D018272:Porins; D012329:RNA, Bacterial; D022661:RNA, Untranslated; D012808:Sigma Factor; D014157:Transcription Factors; C063202:sporulation-specific sigma factors