Molecular epidemiology of the sil streptococcal invasive locus in group A streptococci causing invasive infections in French children.
We found 31 different emm-toxin genotypes among 74 group A streptococcal isolates causing invasive infections in French children. The predominant emm types were emm1 (25%), emm3 (8%), emm4 (8%), emm6 (7%), and emm89 (9%). Sixteen percent of isolates harbored the streptococcal invasive locus, half of them belonging to emm4.
Bidet
Philippe
P
Université Paris VII, UFR Médicale; EA 3105, Laboratoire d'Etudes de Génétique Bactérienne dans les Infections de l'Enfant; Assistance Publique-Hôpitaux de Paris (AP-HP), Service de Microbiologie, Hôpital Robert Debré, Paris, France.
Courroux
Céline
C
Salgueiro
Christophe
C
Carol
Agnès
A
Mariani-Kurkdjian
Patricia
P
Bonacorsi
Stéphane
S
Bingen
Edouard
E
D000293:Adolescent; D000942:Antigens, Bacterial / Q000145:classification / Q000235:genetics; D001425:Bacterial Outer Membrane Proteins / Q000145:classification / Q000235:genetics; D001426:Bacterial Proteins / Q000235:genetics*; D002352:Carrier Proteins / Q000145:classification / Q000235:genetics; D002648:Child; D002675:Child, Preschool; D004269:DNA, Bacterial / Q000032:analysis / Q000235:genetics / Q000302:isolation & purification; D005602:France / Q000453:epidemiology; D006801:Humans; D007223:Infant; D017720:Molecular Epidemiology; D016133:Polymerase Chain Reaction; D013290:Streptococcal Infections / Q000453:epidemiology* / Q000382:microbiology; D013297:Streptococcus pyogenes / Q000145:classification / Q000235:genetics* / Q000472:pathogenicity*; D014774:Virulence
D000942:Antigens, Bacterial; D001425:Bacterial Outer Membrane Proteins; D001426:Bacterial Proteins; D002352:Carrier Proteins; D004269:DNA, Bacterial; C014689:streptococcal M protein