title: [Corneal endothelial cell density following strabismus surgery].
abstract: BACKGROUND
  The short-term impact of eye muscle surgery on the blood-aqueous barrier has been described by iris fluoresceinangiography and laser tyndallometry. The aim of this study was to investigate the long-term effects of eye muscle surgery on the oxygen supply of the anterior segment of the eye by determination of the corneal endothelial cell density.
  
  
  METHODS
  We investigated the corneal endothelial cell density of 32 patients with unilateral rectus muscle surgery pre- and postoperatively (24 cases of primary surgery on 2 horizontal muscles, 4 revision surgeries on 2 horizontal muscles, and 4 primary eye muscle surgeries on the 2 vertical recti including: 3 transpositions of the lateral halves of the vertical recti additional to recession of the medial rectus and one complete transposition of the two vertical recti). Exclusion criteria were previous intraocular surgery and retinal detachment surgery. Mean age at surgery was 37.5 +/- 16.3 (14.5 to 79.9) years. Mean follow-up time was 5.0 +/- 2.2 (1.9 to 10.1) months. The corneal endothelial cell density (CECD) was quantified by means of a specular microscope (EM-1000, Tomey).
  
  
  RESULTS
  The intraocular difference in CECD was not statistically significant either pre- or postoperatively. Mean values were 84 +/- 297 (731 to 700) vs. 52 +/- 357 (600 to 800), p = 0.64. In the subgroups of patients with revision surgery and those with primary eye muscle surgery involving the vertical recti, there was also no significant intraocular difference of CECD.
  
  
  CONCLUSIONS
  Based on the corneal endothelial cell density, there was no evidence of a chronically decreased oxygen supply of the anterior segment even after complex eye muscle surgery.
authors: Augenklinik mit Poliklinik der Universität Erlangen-Nürnberg, Erlangen. Gabriele.Gusek-Schneider@augen.med.uni-erlangen.de
authors: G-C
authors: GC
authors: Gusek-Schneider
authors: R
authors: R
authors: Kamoun
authors: D
authors: D
authors: Klaas
authors: B
authors: B
authors: Seitz
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D004728:Endothelium, Corneal / Q000098:blood supply / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009801:Oculomotor Muscles / Q000473:pathology* / Q000601:surgery*; D013508:Ophthalmologic Surgical Procedures; D010100:Oxygen / Q000378:metabolism; D013285:Strabismus / Q000473:pathology* / Q000601:surgery*; D016896:Treatment Outcome
chemical_list: D010100:Oxygen