title: Drug-eluting stent-induced left anterior descending coronary artery aneurysm: repair by pericardial patch--where are we headed?
abstract: Deployment of drug-eluting stents has been associated with late thrombosis and restenosis on withdrawal of antiplatelet agents. We report a complication of inflammation and localized coronary artery aneurysms immediately adjacent to the stent after 4 years of implantation. Late chronic inflammatory responses may evolve for up to 4 years after sirolimus-eluting stent implantation and can cause weakening, erosion, and aneurysms of the coronary arteries.
authors: Department of Cardiothoracic Surgery, Royal Melbourne Hospital, University of Melbourne, Australia. suviteshluthra@yahoo.com
authors: Suvitesh
authors: S
authors: Luthra
authors: James
authors: J
authors: Tatoulis
authors: Roderic J
authors: RJ
authors: Warren
mesh_terms: D015906:Angioplasty, Balloon, Coronary / Q000009:adverse effects* / Q000379:methods; D003323:Coronary Aneurysm / Q000000981:diagnostic imaging / Q000209:etiology* / Q000601:surgery*; D017023:Coronary Angiography; D023903:Coronary Restenosis / Q000000981:diagnostic imaging / Q000601:surgery; D023921:Coronary Stenosis / Q000000981:diagnostic imaging / Q000628:therapy; D016503:Drug Delivery Systems; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D010496:Pericardium / Q000637:transplantation*; D011475:Prosthesis Failure; D018570:Risk Assessment; D012720:Severity of Illness Index; D020123:Sirolimus / Q000627:therapeutic use; D015607:Stents / Q000009:adverse effects*; D013524:Surgical Flaps; D016896:Treatment Outcome; D014656:Vascular Surgical Procedures / Q000379:methods
chemical_list: D020123:Sirolimus