title: Significant delay of lethal outcome in cancer patients due to peroral administration of Bacillus oligonitrophilus KU-1.
abstract: Treatment of cancer patients remains a serious medical problem and the development of alternative treatment strategies is therefore of great importance. In this connection, we developed a new bacterial-based, anticancer method. Ten cancer patients (three males, seven females) were involved in this study. Bacterial suspension of stationary phase Bacillus oligonitrophilus KU-1 was used as a remedy for peroral administration. In five patients, side effects (sicchasia, slight blood, and intracranial pressure gain) were detected, but all patients showed significant delay of lethal outcome without serious side effects. In conclusion, the suggested method was, in our opinion, a good alternative to conventional chemo- and radiotherapy techniques. In order to evaluate its efficiency for various tumors, a double-blind, placebo-controlled, multicenter study is needed.
authors: Kazan State University, Department of Genetics, Kazan, Russia.
authors: Sergey V
authors: SV
authors: Malkov
authors: Vladimir V
authors: VV
authors: Markelov
authors: Gleb Y
authors: GY
authors: Polozov
authors: Boris I
authors: BI
authors: Barabanschikov
authors: Alexander Y
authors: AY
authors: Kozhevnikov
authors: Maxim V
authors: MV
authors: Trushin
mesh_terms: D000284:Administration, Oral; D000328:Adult; D000368:Aged; D000970:Antineoplastic Agents / Q000008:administration & dosage* / Q000627:therapeutic use; D001407:Bacillus; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000382:microbiology / Q000401:mortality* / Q000628:therapy*; D019936:Probiotics / Q000008:administration & dosage* / Q000627:therapeutic use; D015996:Survival Rate; D013997:Time Factors
chemical_list: D000970:Antineoplastic Agents