Assessment of inflammation in idiopathic orbital myositis with fat-suppressed T2-weighted magnetic resonance imaging.
OBJECTIVE
To evaluate the inflammation in idiopathic orbital myositis by fat-suppressed T2-weighted magnetic resonance imaging (MRI).


METHODS
Observational case series.


METHODS
The inflammation in nine patients with orbital myositis was evaluated with fat-suppressed T2-weighted MRI within three weeks of onset. Patients were mainly treated with steroid pulse therapy and followed to the acute improvement or chronic ocular motility restriction phases.


RESULTS
Each patient was found to have localized inflammations in the extraocular muscles or associated fascial structures. Of the five patients with acute improvement, none had inflammation of the extraocular muscles, whereas the four patients with chronic ocular motility restriction had inflammation of the extraocular muscles.


CONCLUSIONS
These results suggest that acute or chronic pattern in orbital myositis is correlated with the localized inflammation. The inflammation in the extraocular muscles may be one of the factors that lead to the chronic ocular motility restriction.
Kubota
Toshinobu
T
Department of Ophthalmology, National Hospital Organization, Nagoya Medical Center, Naka-ku, Nagoya-shi, Aichi-ken, Japan. ganiky@nnh.hosp.go.jp <ganiky@nnh.hosp.go.jp>
Kano
Hiroshi
H
D000208:Acute Disease; D000328:Adult; D000368:Aged; D002908:Chronic Disease; D005260:Female; D005938:Glucocorticoids / Q000008:administration & dosage; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008775:Methylprednisolone / Q000008:administration & dosage; D008875:Middle Aged; D009220:Myositis / Q000175:diagnosis* / Q000188:drug therapy; D009801:Oculomotor Muscles / Q000473:pathology*; D009915:Orbit / Q000473:pathology*; D016727:Orbital Pseudotumor / Q000175:diagnosis* / Q000188:drug therapy; D020551:Pulse Therapy, Drug; D014057:Tomography, X-Ray Computed
D005938:Glucocorticoids; D008775:Methylprednisolone