title: Dissemination of a capsular and antibiotype variant of the England-9 pneumococcal clone in the Czech Republic.
abstract: Forty-one clinical isolates of serotype 19F Streptococcus pneumoniae resistant to chloramphenicol and/or tetracycline, isolated in the Czech Republic between 1996 and 2005, were analysed by pulsed-field gel electrophoresis and multilocus sequence typing. All but two isolates belonged to a single cluster represented by sequence type 423, a double-locus variant of clone England(14)-9. Interestingly, these two isolates differed from the dominant clone in capsular type as well as antibiotic susceptibility profile.
authors: National Institute of Public Health, Prague, Czech Republic. hzemlickova@szu.cz
authors: H
authors: H
authors: Zemlicková
authors: V
authors: V
authors: Jakubů
authors: P
authors: P
authors: Urbásková
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D015373:Bacterial Typing Techniques; D016000:Cluster Analysis; D018153:Czech Republic / Q000453:epidemiology; D004269:DNA, Bacterial / Q000737:chemistry / Q000235:genetics; D024881:Drug Resistance, Bacterial; D016521:Electrophoresis, Gel, Pulsed-Field; D006801:Humans; D008826:Microbial Sensitivity Tests; D017720:Molecular Epidemiology; D011008:Pneumococcal Infections / Q000453:epidemiology / Q000382:microbiology*; D017422:Sequence Analysis, DNA; D013296:Streptococcus pneumoniae / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification*
chemical_list: D000900:Anti-Bacterial Agents; D004269:DNA, Bacterial