title: How reliable are current docking approaches for structure-based drug design? Lessons from aldose reductase.
authors: Department of Pharmaceutical Chemistry, Philipps-University Marburg, Marbacher Weg 6, 35032 Marburg, Germany.
authors: Matthias
authors: M
authors: Zentgraf
authors: Holger
authors: H
authors: Steuber
authors: Cornelia
authors: C
authors: Koch
authors: Concettina
authors: C
authors: La Motta
authors: Stefania
authors: S
authors: Sartini
authors: Christoph A
authors: CA
authors: Sotriffer
authors: Gerhard
authors: G
authors: Klebe
mesh_terms: D000449:Aldehyde Reductase / Q000037:antagonists & inhibitors* / Q000378:metabolism; D001665:Binding Sites; D003198:Computer Simulation; D018360:Crystallography, X-Ray; D016208:Databases, Factual; D015195:Drug Design; D004791:Enzyme Inhibitors / Q000138:chemical synthesis* / Q000494:pharmacology*; D008024:Ligands; D013329:Structure-Activity Relationship
chemical_list: D004791:Enzyme Inhibitors; D008024:Ligands; D000449:Aldehyde Reductase