[A case of Edwards' syndrome in pregnancy complicated by serologic incompatibility and preeclampsia].
A case of Edwards' syndrome (trisomy 18) diagnosed in the third pregnancy trimester is described. The diagnosis was based on sonographic examination and cytogenetic amniocentesis. Lethal genetic fetal malformation determined the medical indication to preterm delivery. Additionally, serologic incompatibility during pregnancy was observed, as well as pregnancy induced hypertension turning into preeclampsia after the labour action was evoked. A caesarean section due to obstetric indications was done. Phenotype and lethal congenital malformations in the newborn have confirmed of the chromosome aberration prenatally diagnosed.
Murawski
Marek
M
I Katedra i Klinika Ginekologii i Połoznictwa Akademii Medycznej we Wrocławiu. marmurawski@yahoo.co.uk
Gryboś
Marian
M
Zalewska
Dominika
D
Symonowicz
Krzysztof
K
D000015:Abnormalities, Multiple / Q000175:diagnosis*; D000328:Adult; D001787:Blood Group Incompatibility / Q000175:diagnosis*; D002887:Chromosomes, Human, Pair 18; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D011225:Pre-Eclampsia / Q000175:diagnosis*; D011247:Pregnancy; D011263:Pregnancy Trimester, Third; D011296:Prenatal Diagnosis; D013577:Syndrome; D014314:Trisomy / Q000175:diagnosis*