title: A strong association between human earwax-type and apocrine colostrum secretion from the mammary gland.
abstract: Here we provided the first genetic evidence for an association between the degree of apocrine colostrum secretion and human earwax type. Genotyping at the earwax-type locus, rs17822931 within the ABCC11 gene, revealed that 155 of 225 Japanese women were dry-type and 70 wet-type. Frequency of women without colostrum among dry-type women was significantly higher than that among wet-type women (P<0.0002), and the measurable colostrum volume in dry-type women was significantly smaller than in wet-type women (P=0.0341).
authors: Department of Obstetrics and Gynaecology, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki 852-8501, Japan. kiyonori@nagasaki-u.ac.jp
authors: Kiyonori
authors: K
authors: Miura
authors: Koh-ichiro
authors: K
authors: Yoshiura
authors: Shoko
authors: S
authors: Miura
authors: Takako
authors: T
authors: Shimada
authors: Kentaro
authors: K
authors: Yamasaki
authors: Atsushi
authors: A
authors: Yoshida
authors: Daisuke
authors: D
authors: Nakayama
authors: Yoshisada
authors: Y
authors: Shibata
authors: Norio
authors: N
authors: Niikawa
authors: Hideaki
authors: H
authors: Masuzaki
mesh_terms: D018528:ATP-Binding Cassette Transporters / Q000235:genetics; D044466:Asian People; D002571:Cerumen / Q000378:metabolism*; D003126:Colostrum / Q000378:metabolism*; D005260:Female; D006801:Humans; D011110:Polymorphism, Genetic
chemical_list: C435500:ABCC11 protein, human; D018528:ATP-Binding Cassette Transporters