Antithrombotic activity of Russian antithrombin III preparation on the model of induced venous thrombosis.
Antithrombotic activity of Russian preparation Antithrombin III was studied on rat model of induced venous thrombosis. Optimal doses of antithrombin and heparin preventing thrombus growth were determined.
Drozd
N N
NN
Laboratory of Pathology and Pharmacology of Hemostasis, Laboratory for Fractionation of Plasma Proteins, Hematology Research Center, Russian Academy of Medical Sciences, Moscow. nndrozd@mail.ru
Makarov
V A
VA
Miftakhova
N T
NT
Dereza
T L
TL
Azhigirova
M A
MA
D000818:Animals; D000990:Antithrombin III / Q000627:therapeutic use*; D004305:Dose-Response Relationship, Drug; D006493:Heparin / Q000627:therapeutic use; D008297:Male; D051381:Rats; D017208:Rats, Wistar; D012426:Russia; D020246:Venous Thrombosis / Q000188:drug therapy* / Q000473:pathology / Q000517:prevention & control
D000990:Antithrombin III; D006493:Heparin