[Expression of calponin and P63 in human submandibular glands].
OBJECTIVE
To observe the expression of new myoepithelial cell markers calponin and P63 in human submandibular glands.


METHODS
Calponin and P63 antigen in routinely processed human submandibular gland tissues were immunohistochemically demonstrated by monoclonal antibodies to calponin and P63.


RESULTS
Calponin expressed around all acinus and intercalated ducts as linear or punctuate pattern. Positive staining was also noted in peripheral area of some thin striated ducts that connect to intercalated ducts. Subulate or trigonal calponin expression was sometimes seen between the duct dells of striated ducts. P63 expressed mainly in the nucleus of the basal cells of excretory duct.


CONCLUSIONS
Calponin is an ideal gland. P63 labels mainly the basal cells of excretory duct. marker for myoepithelial cells of human submandibular
Lu
Yu-he
YH
Dept. of Oral Pathology, Peking University School of Stomatology, Beijing 100081, China.
Gao
Yan
Y
D000911:Antibodies, Monoclonal; D002135:Calcium-Binding Proteins; D004847:Epithelial Cells; D006801:Humans; D008840:Microfilament Proteins; D013363:Submandibular Gland; D000096985:Calponins
D000911:Antibodies, Monoclonal; D002135:Calcium-Binding Proteins; D008840:Microfilament Proteins; D000096985:Calponins