Identification of a novel HLA-B*58 allele, B*5813, by sequence-based typing of DNA from Korean baby cord blood.
The novel HLA-B*5813 allele was identified in the cord blood of a Korean baby by sequence-based typing. This allele shows a sequence identical to that of HLA-B*5801, except for a nucleotide substitution that changes GAG to AAG at codon 128, resulting in an amino acid change from glutamic acid to lysine in the protein.
Yoon
S
S
School of Life Science and Biotechnology, Pochon CHA University, Kyunggi-do 463-836, Korea.
Baek
J-Y
JY
Hur
S-S
SS
Kwon
O-J
OJ
Kwack
K
K
D044466:Asian People; D001483:Base Sequence; D005312:Fetal Blood / Q000378:metabolism*; D014644:Genetic Variation; D015235:HLA-B Antigens / Q000235:genetics*; D006650:Histocompatibility Testing; D006801:Humans; D007231:Infant, Newborn; D007438:Introns; D007723:Korea; D008969:Molecular Sequence Data; D011110:Polymorphism, Genetic; D017422:Sequence Analysis, DNA / Q000379:methods*; D012689:Sequence Homology, Nucleic Acid
D015235:HLA-B Antigens; C520563:HLA-B*58:13 antigen