Late-onset mania with psychosis associated with hypothyroidism in an elderly Chinese lady.
Late-onset bipolar disorder is rare and can be precipitated by organic brain disorders. While the association between hyperthyroidism and mania is well described, mania or hypomania precipitated by hypothyroidism is rare. The authors present late-onset bipolar disorder in a 72-year-old woman presenting with mania and psychosis, which appear to have been precipitated by autoimmune hypothyroidism. This case shows the importance of ascertaining the thyroid status in patients with mood and psychotic disorders, especially in elderly patients and in patients lacking prominent signs of thyroid disease.
Tor
P C
PC
Department of Psychological Medicine, National University Hospital, 5 Lower Kent Ridge Road, Singapore 119074. torphernchern@gmail.com
Lee
H Y
HY
Fones
C S L
CS
D000368:Aged; D014150:Antipsychotic Agents / Q000009:adverse effects; D001714:Bipolar Disorder / Q000209:etiology*; D003987:Dibenzothiazepines / Q000009:adverse effects; D005260:Female; D006801:Humans; D007037:Hypothyroidism / Q000139:chemically induced / Q000188:drug therapy / Q000523:psychology*; D011618:Psychotic Disorders / Q000209:etiology*; D000069348:Quetiapine Fumarate; D013974:Thyroxine / Q000627:therapeutic use
D014150:Antipsychotic Agents; D003987:Dibenzothiazepines; D000069348:Quetiapine Fumarate; D013974:Thyroxine