title: Linking the epigenetic 'language' of covalent histone modifications to cancer.
abstract: Covalent modifications of histones, such as acetylation, methylation, and phosphorylation, and other epigenetic modulations of the chromatin, such as methylation of DNA and ATP-dependent chromatin reorganisation, can play a major part in the multistep process of carcinogenesis, with far-reaching implications for human biology and human health. This review focuses on how aberrant covalent histone modifications may contribute to the development of a variety of human cancers, and discusses the recent findings with regard to potential therapies.
authors: Laboratory of Chromatin Biology, The Rockefeller University, New York, NY 10021, USA
authors: S B
authors: SB
authors: Hake
authors: A
authors: A
authors: Xiao
authors: C D
authors: CD
authors: Allis