Short-column CE coupled with inductively coupled plasma MS for high-throughput speciation analysis of chromium.
A method was developed for high-throughput speciation analysis of chromium by on-line coupling of short-column capillary electrophoresis (SC-CE) and inductively coupled plasma mass spectrometry (ICP-MS). Baseline separation of Cr(III) and Cr(VI) was achieved within 1 min by SC-CE in a 15 cm x 75 microm id fused-silica capillary at 6 kV using 15 mM HNO(3) as running electrolyte. The precisions (RSD, n = 5) of migration time and peak area for Cr(III) and Cr(VI) were in the range of 1.8-2.4% and 2.2-5.7%, respectively. The limits of detection (3sigma) of Cr(III) and Cr(VI) were 1.8 and 1.9 microg/L, respectively. The synthesized samples containing Cr(III) and Cr(VI) species were determined by the developed SC-CE-ICP-MS hyphenated technique, and the recoveries of Cr(III) and Cr(VI) in the synthesized samples were in the range of 103-110% and 90-108%, respectively.
Li
Bao-Hui
BH
Key Laboratory of Functional Polymer Materials, Ministry of Education, Research Center for Analytical Sciences, College of Chemistry, Nankai University, Tianjin, P. R. China.
Yan
Xiu-Ping
XP
D002857:Chromium / Q000737:chemistry / Q000302:isolation & purification*; D019075:Electrophoresis, Capillary / Q000295:instrumentation* / Q000379:methods; D004867:Equipment Design / Q000379:methods; D017022:Flow Injection Analysis / Q000379:methods; D013058:Mass Spectrometry / Q000379:methods*; D008904:Miniaturization; D009330:Nebulizers and Vaporizers; D017942:Nitric Acid / Q000737:chemistry; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity
D002857:Chromium; D017942:Nitric Acid