Association between periodontal disease and acute coronary syndrome.
OBJECTIVE
To evaluate the relationship between PD and ACS and the association of PD and periodontitis in ACS patients.


METHODS
Fifty-eight ACS patients and 57 controls with no history of coronary artery disease (CAD) were included in the study.


METHODS
arterial hypertension, diabetes, dyslipidemia, obesity, history of CAD, cigarette smoking, and interleukin-1beta gene polymorphism.


RESULTS
One hundred and fifteen subjects were enrolled in the study. In the ACS group, 58 patients were evaluated, 32 of whom (55.2%) were male and 26 (44.8%), female. In the control group, 57 subjects were evaluated, 32 (56.1%) of whom were male and 25 (43.9%), female. Periodontal disease was diagnosed in 26 (44.8%) ACS patients and 15 (26.6%) control patients (beta2 = 4.43, p = 0.04). In a logistic regression analysis, the odds ratio for association between PD and ACS was 1.8 (95% CI: 1.0-5.0); p = 0.24. The odds ratio for association of periodontitis with ACS was 4.5 (95% CI: 1.3-15.6); p = 0.019.


CONCLUSIONS
No independent association was found between PD and ACS. There was an independent association between periodontitis and ACS.
Rech
Rafael Luiz
RL
Hospital São Lucas, Faculdade de Odontologia, PUC-RS, Porto Alegre, RS, Brazil.
Nurkin
Natálio
N
da Cruz
Ivana
I
Sostizzo
Fabiano
F
Baião
Carolina
C
Perrone
José Antônio
JA
Wainstein
Rodrigo
R
Pretto
Daniela
D
Manenti
Euler Roberto Fernandes
ER
Bodanese
Luiz Carlos
LC
D000368:Aged; D000789:Angina, Unstable / Q000150:complications*; D016022:Case-Control Studies; D004562:Electrocardiography; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D009203:Myocardial Infarction / Q000150:complications*; D010510:Periodontal Diseases / Q000150:complications*; D010512:Periodontal Index; D012307:Risk Factors