Ellagic acid glycosides from Turpinia ternata.
Bioassay-guided fractionation of the methanolic extract of Turpinia ternata stems, has led to the isolation of the new ellagic acid derivative 3,4'-di-O-methylellagic acid-4-O-alpha-L-arabinofuranoside (1), and the known compounds ellagic acid (2), 3-O-methyl ellagic acid (3), 3-O-methylellagic acid-3'-O-alpha-L-rhamnopyranoside (4), and 3,3'-di-O-methylellagic acid-4'-O-alpha-D-glucopyranoside (5). Their structures were elucidated by extensive spectroscopic methods. Compounds 1, 3, and 4 showed moderate antioxidant activity against DPPH free radical, whereas compound 1 was found to be moderately cytotoxic against Artemia salina larvae.
Matthew
Susan
S
CQFB/REQUIMTE, FCT-UNL, Caparica, Portugal. susmatt111@yahoo.com
Kao
Kuo-Chin
KC
Chang
Yuan-Shiun
YS
Abreu
Pedro
P
D000818:Animals; D001156:Artemia; D001578:Benzopyrans / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D001713:Biphenyl Compounds / Q000378:metabolism; D003603:Cytotoxins / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D004610:Ellagic Acid / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D016166:Free Radical Scavengers / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D006834:Hydrazines / Q000378:metabolism; D019906:Nuclear Magnetic Resonance, Biomolecular; D009904:Optical Rotation; D010851:Picrates; D018515:Plant Leaves / Q000737:chemistry; D016339:Spectrometry, Mass, Fast Atom Bombardment; D013056:Spectrophotometry, Ultraviolet; D017550:Spectroscopy, Fourier Transform Infrared; D053719:Tandem Mass Spectrometry; D014197:Trees / Q000737:chemistry*
D001578:Benzopyrans; D001713:Biphenyl Compounds; D003603:Cytotoxins; D016166:Free Radical Scavengers; D006027:Glycosides; D006834:Hydrazines; D010851:Picrates; D004610:Ellagic Acid; C004931:1,1-diphenyl-2-picrylhydrazyl