title: New developments in surgery: Natural Orifice Transluminal Endoscopic Surgery (NOTES).
abstract: Natural orifice transluminal endoscopic surgery refers to the method of accessing the abdominal cavity through a natural orifice under endoscopic visualization. Since its introduction in 2004, numerous reports have been published describing different surgical interventions. Recently, a group of expert laparoscopic surgeons and endoscopists outlined the limitations of this approach and issued recommendations for progress toward human trials. Herein we review the published data and propose a series of questions to be considered for future investigations. We also address the controversy involved in the incorporation of this new technology into surgical practice.
authors: Duke Endosurgery Center, Departments of Surgery and Anesthesiology, Duke University Medical Center, Durham, NC 27710, USA. sebastian.delafuente@duke.edu
authors: Sebastian G
authors: SG
authors: de la Fuente
authors: Eric J
authors: EJ
authors: Demaria
authors: James D
authors: JD
authors: Reynolds
authors: Dana D
authors: DD
authors: Portenier
authors: Aurora D
authors: AD
authors: Pryor
mesh_terms: D000818:Animals; D019723:Endoscopes / Q000639:trends*; D016145:Endoscopy, Digestive System / Q000639:trends*; D006801:Humans; D012955:Societies, Medical; D014481:United States