Nevus type in dermoscopy is related to skin type in white persons.
BACKGROUND
Dermoscopic classification of acquired melanocytic nevi (AMN) is based on the evaluation of 3 main criteria-global pattern, pigment distribution, and color.


OBJECTIVE
To determine whether these features are different in AMN in white people with different skin types (STs) according to the Fitzpatrick classification.


METHODS
Digital dermoscopic images of AMN were evaluated, and the correlation of the 3 main dermoscopic criteria with patient ST was analyzed.


METHODS
Consecutive patients were recruited from 7 pigmented lesion clinics between June 1, 2004, and June 30, 2005. Patients For each patient, the ST (I [always burns, never tans] to IV [rarely burns, tans with ease]) was scored, and 1 representative AMN (defined as the AMN showing a dermoscopic typology that is repeatedly seen in the same patient) was selected and photographed.


METHODS
The distribution of the dermoscopic criteria of AMN in patients with different STs was calculated by univariate analysis. Differences in prevalence were tested using the chi(2) test. The correlation between dermoscopic criteria and ST, adjusted for age, sex, and enrolling center, was evaluated by calculating odds ratios and 95% confidence intervals by logistic regression analysis.


RESULTS
Of 680 included patients, dermoscopic analysis revealed significant differences in the prevalent nevus pattern in the 4 ST groups. Light brown AMN with central hypopigmentation were associated with ST I, and ST IV was associated with the so-called black nevus (P<.001), typified by reticular pattern, central hyperpigmentation, and dark brown coloration. A significant association was also found between multifocal pattern and ST II and ST III.


CONCLUSIONS
The dermoscopic nevus type varies according to different ST in white people. This knowledge may have an effect on obtaining for biopsy lesions that exhibit unusual dermoscopic patterns when patient ST is considered.
Zalaudek
Iris
I
Department of Dermatology, Medical University of Graz, Graz, Austria. iris.zaludek@meduni-graz.at
Argenziano
Giuseppe
G
Mordente
Ines
I
Moscarella
Elvira
E
Corona
Rosamaria
R
Sera
Francesco
F
Blum
Andreas
A
Cabo
Horacio
H
Di Stefani
Alessandro
A
Hofmann-Wellenhof
Rainer
R
Johr
Robert
R
Langford
David
D
Malvehy
Josep
J
Kolm
Isabel
I
Sgambato
Anna
A
Puig
Susana
S
Soyer
H Peter
HP
Kerl
Helmut
H
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D046169:Dermoscopy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009508:Nevus, Pigmented / Q000145:classification* / Q000473:pathology*; D012878:Skin Neoplasms / Q000145:classification* / Q000473:pathology*; D044465:White People