title: Consumer exposure to substances in plastic packaging. I. Assessment of the contribution of styrene from yogurt pots.
abstract: A generic methodology for the assessment of consumer exposure to substances migrating from packaging materials into foodstuffs during storage is presented. Consumer exposure at the level of individual households is derived from the probabilistic modeling of the contamination of all packed food product units (e.g. yogurt pot, milk bottle, etc.) consumed by a given household over 1 year. Exposure of a given population is estimated by gathering the exposure distributions of individual households to suitable weights (conveniently, household sizes). Calculations are made by combining (i) an efficient resolution of migration models and (ii) a methodology utilizing different sources of uncertainty and variability. The full procedure was applied to the assessment of consumer exposure to styrene from yogurt pots based on yearly purchase data of more than 5400 households in France (about 2 million yogurt pots) and an initial concentration c0 of styrene in yogurt pot walls, which is assumed to be normally distributed with an average value of 500 mg kg-1 and a standard deviation of 150 mg kg-1. Results are discussed regarding both sensitivity of the migration model to boundary conditions and household practices. By assuming a partition coefficient of 1 and a Biot number of 100, the estimated median household exposure to styrene ranged between 1 and 35 microg day-1 person-1 (5th and 95th percentiles) with a likely value of 12 microg day-1 person-1 (50th percentile). It was found that exposure does not vary independently with the average consumption rate and contact times. Thus, falsely assuming a uniform contact time equal to the sell-by-date for all yogurts overestimates significantly the daily exposure (5th and 95th percentiles of 2 and 110 microg day-1 person-1, respectively) since high consumers showed quicker turnover of stock.
authors: UMR Fractionnement des Agro-Ressources et Emballage, INRA 614, Moulin de la Housse, 51687 Reims Cedex 2, France. olivier.vitrac@reims.inra.fr
authors: Olivier
authors: O
authors: Vitrac
authors: Jean-Charles
authors: JC
authors: Leblanc
mesh_terms: D000328:Adult; D002648:Child; D005260:Female; D005504:Food Analysis / Q000379:methods*; D005506:Food Contamination / Q000032:analysis*; D018857:Food Packaging; D005602:France; D006801:Humans; D008297:Male; D008956:Models, Chemical; D018570:Risk Assessment; D020058:Styrene / Q000032:analysis* / Q000633:toxicity; D015014:Yogurt / Q000032:analysis*
chemical_list: D020058:Styrene