title: The diagnosis, staging, and treatment options for mycosis fungoides.
abstract: BACKGROUND
  Cutaneous T-cell lymphoma (CTCL) represents a spectrum of diseases composed of malignant T lymphocytes. The most common type is mycosis fungoides (MF). An accurate diagnosis of early MF may be difficult because of the varied clinical and histologic expressions of the disease.
  
  
  METHODS
  The authors review the epidemiology, possible risk factors, clinical manifestations, diagnostic techniques, staging, prognosis, and treatment options for MF.
  
  
  RESULTS
  The varied and often nonspecific clinical and histologic presentations of MF may delay diagnosis and staging, thus necessitating further studies such as immunophenotyping and T-cell receptor gene rearrangement analysis.
  
  
  CONCLUSIONS
  A multidisciplinary approach to the diagnosis, staging, and treatment of MF assists in optimizing outcomes from management of patients with this disease.
authors: Cutaneous Oncology Program, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL 33612, USA.
authors: Connie A
authors: CA
authors: Keehn
authors: Iriana P
authors: IP
authors: Belongie
authors: Galina
authors: G
authors: Shistik
authors: Neil A
authors: NA
authors: Fenske
authors: L Frank
authors: LF
authors: Glass
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use; D006801:Humans; D009182:Mycosis Fungoides / Q000175:diagnosis* / Q000453:epidemiology / Q000628:therapy; D009367:Neoplasm Staging; D010789:Phototherapy; D011379:Prognosis; D012307:Risk Factors; D012878:Skin Neoplasms / Q000175:diagnosis* / Q000188:drug therapy
chemical_list: D000970:Antineoplastic Agents