title: Estimated intake of intense sweeteners from non-alcoholic beverages in Denmark.
abstract: In 1999, 116 samples of non-alcoholic beverages were analysed for the intense sweeteners cyclamate, acesulfame-K, aspartame and saccharin. High contents of cyclamate close to the maximum permitted level in 1999 of 400 mg l(-1) were found in many soft drinks. The estimated intake of the sweeteners was calculated using the Danish Dietary Survey based on 3098 persons aged 1-80 years. The estimated intake with 90th percentiles of 0.7, 4.0 and 0.2 mg kg(-1) body weight (bw) day(-1) for acesulfame-K, aspartame and saccharin, respectively, was much lower than the acceptable daily intake (ADI) values of 15, 40 and 2.5 mg kg(-1) bw day(-1) for acesulfame-K, aspartame and saccharin, respectively. However, the 90th percentile of the estimated cyclamate intake in 1-3 year olds was close to the ADI value of 7 mg kg(-1) bw day(-1); and the 99th percentile in the 1-10 year olds far exceeded the ADI value. Boys aged 7-10 years had a significantly higher estimated intake of cyclamate than girls. The 90th percentile for the whole population was 1.8 mg kg(-1) bw day(-1). After the reduction in the maximum permitted level in the European Union in 2004 from 400 to 250 mg cyclamate l-1, the exposure in Denmark can also be expected to be reduced. A new investigation in 2007 should demonstrate whether the problem with high cyclamate intake is now solved.
authors: Danish Institute for Food and Veterinary Research, Torben Mørkhøj Bygade 19, Søborg DK-2860, Denmark. tol@dfvf.dk
authors: T
authors: T
authors: Leth
authors: N
authors: N
authors: Fabricius
authors: S
authors: S
authors: Fagt
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D001218:Aspartame / Q000008:administration & dosage / Q000032:analysis; D001628:Beverages / Q000032:analysis*; D002253:Carbonated Beverages / Q000032:analysis; D002648:Child; D002675:Child, Preschool; D002851:Chromatography, High Pressure Liquid / Q000379:methods; D003494:Cyclamates / Q000008:administration & dosage / Q000032:analysis; D003718:Denmark; D004034:Diet Surveys; D005504:Food Analysis / Q000379:methods; D006801:Humans; D007223:Infant; D008452:Maximum Allowable Concentration; D008875:Middle Aged; D012439:Saccharin / Q000008:administration & dosage / Q000032:analysis; D013549:Sweetening Agents / Q000008:administration & dosage* / Q000032:analysis; D013843:Thiazines / Q000008:administration & dosage / Q000032:analysis
chemical_list: D003494:Cyclamates; D013549:Sweetening Agents; D013843:Thiazines; D012439:Saccharin; C006362:acetosulfame; D001218:Aspartame