title: On-chip erythrocyte deformability test under optical pressure.
abstract: This paper presents a novel method for an on-chip erythrocyte deformability test under optical pressure, especially to enhance the level of sensitivity with respect to the detection of cancerous diseases. To demonstrate the performance and sensitivity of the combined method, we introduce the concept of transit velocity, a modified elongation index, and shape recovery time of individual erythrocytes in a strictly confined region (2 microm deep, 4 microm wide, and 100 microm long). Finally, we investigate a synergy or convergence effect due to the combination of these parameters for in situ detection of cancerous diseases under optical pressure.
authors: School of Mechanical and Aerospace Engineering, Seoul National University, San 56-1 Shinlim, Kwanak, Seoul 151-742, South Korea.
authors: Won Gu
authors: WG
authors: Lee
authors: Hyunwoo
authors: H
authors: Bang
authors: Hoyoung
authors: H
authors: Yun
authors: Joonmo
authors: J
authors: Lee
authors: Junha
authors: J
authors: Park
authors: Jung Kyung
authors: JK
authors: Kim
authors: Seok
authors: S
authors: Chung
authors: Keunchang
authors: K
authors: Cho
authors: Chanil
authors: C
authors: Chung
authors: Dong-Chul
authors: DC
authors: Han
authors: Jun Keun
authors: JK
authors: Chang
mesh_terms: D000328:Adult; D004548:Elasticity; D004903:Erythrocyte Aggregation; D004907:Erythrocyte Deformability; D004912:Erythrocytes / Q000166:cytology*; D006801:Humans; D009369:Neoplasms / Q000097:blood / Q000175:diagnosis; D055095:Optics and Photonics; D011312:Pressure; D012680:Sensitivity and Specificity; D013997:Time Factors