Olmsted syndrome in an Iranian family: report of two new cases.
Olmsted syndrome is a rare congenital entity characterized by combination of symmetrical, sharply-defined palmoplantar keratoderma with flexion deformities of the digits, periorificial keratosis, perianal involvement, onychodystrophy, and variable leukokeratosis. Herein, we report two new related male patients--the third familial cases of Olmsted syndrome--one with the full-blown spectrum of the syndrome, and the other with early signs and symptoms of the disorder.
Yaghoobi
Reza
R
Department of Dermatology, Jondi Shapour University of Medical Sciences, Ahwaz, Iran. yaghoobi_rz@yahoo.com
Omidian
Mohammad
M
Sina
Niloofar
N
Abtahian
Seyyed-Arash
SA
Panahi-Bazaz
Mahmoud-Reza
MR
D000328:Adult; D002648:Child; D018450:Disease Progression; D006801:Humans; D007492:Iran; D007645:Keratoderma, Palmoplantar / Q000175:diagnosis*; D008297:Male; D013577:Syndrome