title: [Prevalence of tannerella forsythensis in subgingival microflora of Chinese chronic periodontitis patients].
abstract: OBJECTIVE
  The aim of this study was to investigate the prevalence of T. forsythensis in Chinese chronic periodontitis patients, and correlate it with clinical parameters.
  
  
  METHODS
  108 chronic periodontitis patients were selected according to clinical criteria. In each patient, subgingival plaque samples were collected from two of the periodontitis involved molar sites with the deepest periodontal pocket depth(diseased sites) and one healthy gingival sulcus (healthy sites). T. forsythensis was detected by 16S rRNA polymerase chain reaction. Clinical assessments including probing depth, clinical attachment loss and bleeding on probing, were made at sampling sites.
  
  
  RESULTS
  The prevalence of Tforsythensis in diseased sites and healthy sites was 59.72% and 3.70% respectively (P < 0.001). The prevalence of T. forsythensis was significantly higher in deeper pockets and more serious clinical attachment loss, Spearman rank correlation coefficient was 0.48 and 0.51 respectively. The prevalence of T. forsythensis in BOP (+)sites was 61.31%, and in BOP(-) sites was 8.80% (P < 0.001).
  
  
  CONCLUSIONS
  The prevalence of T. forsythensis was significantly correlated with clinical parameters, suggesting that T. forsythensis is closely related to chronic periodontitis in the Chinese population.
authors: Key Laboratory of Oral Biomedical Engineering of Ministry of Education, Sichuan University, Chengdu 610041, China.
authors: He
authors: H
authors: Yang
authors: Ya-fei
authors: YF
authors: Wu
authors: Lei
authors: L
authors: Zhao
authors: Shu
authors: S
authors: Meng
mesh_terms: D000328:Adult; D001419:Bacteria; D055113:Chronic Periodontitis; D003773:Dental Plaque; D005260:Female; D005881:Gingiva; D006801:Humans; D008297:Male; D008875:Middle Aged; D010514:Periodontal Pocket; D010518:Periodontitis; D016133:Polymerase Chain Reaction; D015995:Prevalence; D012336:RNA, Ribosomal, 16S
chemical_list: D012336:RNA, Ribosomal, 16S