The synthesis and initial characterization of an immobilized purinergic receptor (P2Y1) liquid chromatography stationary phase for online screening.
Moaddel
Ruin
R
Gerontology Research Center, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224, USA. moaddelru@grc.nia.nih.gov
Calleri
Enrica
E
Massolini
Gabriella
G
Frazier
Chester R
CR
Wainer
Irving W
IW
D000244:Adenosine Diphosphate / Q000031:analogs & derivatives* / Q000737:chemistry; D001254:Astrocytoma / Q000737:chemistry*; D001665:Binding Sites; D001667:Binding, Competitive; D002846:Chromatography, Affinity / Q000379:methods*; D003838:Deoxyadenine Nucleotides / Q000737:chemistry; D006801:Humans; D008567:Membranes, Artificial; D058910:Purinergic P2 Receptor Agonists; D058919:Purinergic P2 Receptor Antagonists; D018048:Receptors, Purinergic P2 / Q000096:biosynthesis / Q000737:chemistry*; D058472:Receptors, Purinergic P2Y1; D012680:Sensitivity and Specificity; D013873:Thionucleotides / Q000737:chemistry*; D014162:Transfection; D014407:Tumor Cells, Cultured / Q000737:chemistry*
C465253:2-chloro-N6-methyl-(N)-methanocarba-2'-deoxyadenosine-3',5'-bisphosphate; C495475:2-iodo-N(6)-methyl-(N)-methanocarba-2'-deoxyadenosine-3',5'-bisphosphate; D003838:Deoxyadenine Nucleotides; D008567:Membranes, Artificial; C546382:P2RY1 protein, human; D058910:Purinergic P2 Receptor Agonists; D058919:Purinergic P2 Receptor Antagonists; D018048:Receptors, Purinergic P2; D058472:Receptors, Purinergic P2Y1; D013873:Thionucleotides; C002480:methylthio-ADP; D000244:Adenosine Diphosphate