One-pot synthesis of substituted 2-aminobenzo[b]thiophenes.
Reaction of 1-(2-chloro-5-nitrophenyl)ethanone 1, via Willgerodt-Kindler routes, using the primary and secondary amines 2a-k resulted in a simple, efficient three-component one-pot synthesis of 2-aminobenzo[b]thiophenes 3a-k.
Solovyev
Andrey Y
AY
Center for Photochemical Sciences, Bowling Green State University, Bowling Green, Ohio 43403, USA.
Androsov
Dmitry A
DA
Neckers
Douglas C
DC