AmBisome treatment of pulmonary aspergillosis in a patient with tuberculosis.
This case report describes the history of a patient with pulmonary tuberculosis. As part of the diagnostic work-up a transthoracic biopsy was performed which resulted in a lung collapse. After one month of standard therapy for tuberculosis, the patient was admitted to our hospital for a clinical and surgical re-evaluation. Microbiological examination showed the presence of Aspergillus niger and Pseudomonas aeruginosa. Treatment with AmBisome, ciprofloxacin and imipenem was started: the patient responded well with good clinical improvement. After 5 months of anti-tuberculous therapy, culture of pleural fluid was negative; the right lung remained collapsed but sterilization of the pleura will allow future surgery.
Viggiani
Pietro
P
Unit of Thisiology, Department of Respiratory Disease, Sondalo Hospital, Italy.
Besozzi
Giorgio
G
D000368:Aged; D000666:Amphotericin B / Q000627:therapeutic use*; D000935:Antifungal Agents / Q000627:therapeutic use*; D001228:Aspergillosis / Q000150:complications* / Q000188:drug therapy*; D006801:Humans; D008172:Lung Diseases, Fungal / Q000150:complications* / Q000188:drug therapy*; D008297:Male; D014397:Tuberculosis, Pulmonary / Q000150:complications*
D000935:Antifungal Agents; C068538:liposomal amphotericin B; D000666:Amphotericin B