Novel antipseudomonal treatment approaches.
Preventing and treating adequately Pseudomonas aeruginosa infection in the context of cystic fibrosis remains one of the most challenging topics of basic and clinical research in 2005. This state of the art review of antipseudomonal treatments describes some of the novel therapeutic approaches under development: active and passive immunisation, prevention of Pseudomonas aeruginosa adherence to cell surfaces, antibiofilm strategies, novel antimicrobial agents and inhaled dry powder antibiotics.
Davies
J C
JC
Dept of Gene Therapy, National Heart and Lung Institute, Imperial College, Emmanuel Kaye Building, Manresa Rd, London SW3 6LR. j.c.davies@imperial.ac.uk
D002648:Child; D003550:Cystic Fibrosis / Q000150:complications; D006801:Humans; D011552:Pseudomonas Infections / Q000188:drug therapy* / Q000209:etiology