title: Wound therapy with autologous bone marrow stem cells in diabetic patients with ischaemia-induced tissue ulcers affecting the lower limbs.
abstract: Previous studies suggest that autologous transplantation of bone marrow mononuclear cells is safe and effective in inducing therapeutic angiogenesis in patients with peripheral arterial occlusive disease (PAOD). Here we discuss a multidisciplinary approach to treating PAOD with a focus on the use of angiological diagnostic tools. We conclude that our autologous stem cell therapy is working in this patient and it is a potential new therapeutic option for diabetic patients with chronic foot ulcers induced by critical limb ischaemia.
authors: S
authors: S
authors: Kirana
authors: B
authors: B
authors: Stratmann
authors: D
authors: D
authors: Lammers
authors: M
authors: M
authors: Negrean
authors: A
authors: A
authors: Stirban
authors: P
authors: P
authors: Minartz
authors: H
authors: H
authors: Koerperich
authors: M H
authors: MH
authors: Gastens
authors: C
authors: C
authors: Götting
authors: W
authors: W
authors: Prohaska
authors: K
authors: K
authors: Kleesiek
authors: D
authors: D
authors: Tschoepe
mesh_terms: D003924:Diabetes Mellitus, Type 2 / Q000150:complications; D017719:Diabetic Foot / Q000628:therapy*; D006801:Humans; D007511:Ischemia / Q000150:complications*; D007866:Leg / Q000098:blood supply*; D008297:Male; D008875:Middle Aged; D033581:Stem Cell Transplantation / Q000379:methods*; D016896:Treatment Outcome