Integration of a nanoporous platinum thin film into a microfluidic system for non-enzymatic electrochemical glucose sensing.
In this paper, we describe an amperometric-type enzymeless glucose sensing system based on a nanoporous platinum (Pt) electrode embedded in a microfluidic chip. This microchip system is comprised of a microfluidic transport channel network and a miniaturized electrochemical cell for nonenzymatic glucose sensing. Sample and buffer solutions were transferred to the cell by programmed electroosmotic flow (EOF). A nanoporous Pt electrode with the roughness factor of 200.6 was utilized to determine glucose concentrations in phosphate buffered saline (PBS) by the direct oxidation of glucose, without any separation process. The sensitivity of the developed system is 1.65 microA cm-2 mM-1 in the glucose concentration range from 1-10 mM in PBS.
Joo
Segyeong
S
Interdisciplinary Program-Biomedical Engineering Major, Seoul National University, Korea.
Park
Sejin
S
Chung
Taek Dong
TD
Kim
Hee Chan
HC
D004563:Electrochemistry; D004798:Enzymes; D005947:Glucose / Q000032:analysis*; D046210:Microfluidic Analytical Techniques / Q000295:instrumentation*; D036103:Nanotechnology / Q000295:instrumentation*; D010984:Platinum / Q000737:chemistry*; D016062:Porosity
D004798:Enzymes; D010984:Platinum; D005947:Glucose