Resolution of Chiari I malformation following acetazolamide therapy.
A 25-year-old obese woman developed headaches and visual blurring. Examination showed papilledema and cranial MRI showed a large Chiari I malformation. Acetazolamide was initiated and a repeat cranial MRI surprisingly showed resolution of the Chiari I malformation. Chiari I malformation associated with papilledema has never been shown to resolve with acetazolamide therapy.
Vaphiades
Michael S
MS
Department of Ophthalmology, University of Alabama at Birmingham, AL 35233, USA. vaphiades@uab.edu
Braswell
Ronald
R
D000086:Acetazolamide / Q000627:therapeutic use*; D000328:Adult; D001139:Arnold-Chiari Malformation / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy*; D004232:Diuretics / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007427:Intracranial Pressure; D007429:Intraocular Pressure; D008279:Magnetic Resonance Imaging; D010211:Papilledema / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology
D004232:Diuretics; D000086:Acetazolamide