title: Quality of life (QOL) in menopause.
abstract: Quality of life (QOL) is generally not precisely defined or measured. This has resulted in confusing and often misleading conclusions in multiple publications, including those coming from both the HERS and the WHI writing groups. Health-related QOL and global QOL are accurately defined, and current instruments for measuring them are available. In the continuing effort to determine the true risks and benefits of postmenopausal hormone usage, it is critical that the full spectrum of effects be measured. There is no excuse for future studies on hormone use not to include well-validated instruments for measuring QOL and for not reporting those effects as part of the rest of the study. Questionnaire instruments can often provide more information than many of the invasive tests that are part of contemporary trials. They also add little cost, yet can be invaluable in the analysis of real cost-effectiveness of interventions in contemporary women's health care. Beyond safety and efficacy evaluation of drug therapies, there is an absolute need to know about the real impact of these therapies on overall quality of life.
authors: Consultant in Women's Health, The Cleveland Clinic, Professor Emeritus, Case Western Reserve University, Cleveland, OH, United States. Utian@menopause.org
authors: Wulf H
authors: WH
authors: Utian
mesh_terms: D005260:Female; D020249:Hormone Replacement Therapy / Q000379:methods / Q000523:psychology*; D006801:Humans; D047648:Perimenopause / Q000523:psychology*; D011788:Quality of Life; D016032:Randomized Controlled Trials as Topic; D011795:Surveys and Questionnaires; D009626:Terminology as Topic