title: Visceral sensory inputs to the endocrine hypothalamus.
abstract: Interoceptive feedback signals from the body are transmitted to hypothalamic neurons that control pituitary hormone release. This review article describes the organization of central neural pathways that convey ascending visceral sensory signals to endocrine neurons in the paraventricular (PVN) and supraoptic nuclei (SON) of the hypothalamus in rats. A special emphasis is placed on viscerosensory inputs to corticotropin releasing factor (CRF)-containing PVN neurons that drive the hypothalamic-pituitary-adrenal axis, and on inputs to magnocellular PVN and SON neurons that release vasopressin (AVP) or oxytocin (OT) from the posterior pituitary. The postnatal development of these ascending pathways also is considered.
authors: Department of Neuroscience, University of Pittsburgh, Pittsburgh, PA 15260, USA. rinaman@pitt.edu
authors: Linda
authors: L
authors: Rinaman
mesh_terms: D000818:Animals; D007031:Hypothalamus / Q000033:anatomy & histology*; D009474:Neurons / Q000166:cytology / Q000378:metabolism; D009475:Neurons, Afferent / Q000166:cytology / Q000502:physiology*; D009479:Neuropeptides / Q000378:metabolism; D010902:Pituitary Gland / Q000294:innervation / Q000502:physiology; D014781:Viscera / Q000294:innervation*
chemical_list: D009479:Neuropeptides