title: [Two cases of Pseudomonas aeruginosa neonatal meningitis treated by ciprofloxacine].
abstract: Two cases of Pseudomonas aeruginosa neonatal meningitis are reported. Case 1 occurred on day 6 of life, at home, in a full term newborn. Favourable outcome was obtained with a treatment associating ceftazidime, 21 days, gentamicin, 10 days and ciprofloxacin, 10 days. Case no 2 was a nosocomial meningitis in a 32 weeks and 4 days gestational age premature newborn. Despite in vitro effective antibiotherapy with ceftazidime, netilmicine and ciprofloxacine, six cerebral abscesses were observed during the second week of treatment. Ceftazidime was stopped after 6 weeks and ciprofloxacine prolonged until neuroradiological cure of cerebral lesions at one year of age. Normal outcome was observed at 3 and 4 and half year of age. Therapeutic indications and clinical tolerance of ciprofloxacine in neonatal meningitis are discussed.
authors: Service de néonatologie et de réanimation néonatale, hôpital Robert-Debré, 48, boulevard Serurier, 75010 Paris, France.
authors: D
authors: D
authors: Tanase-Derkaoui
authors: P
authors: P
authors: le Huidoux
authors: C
authors: C
authors: Farnoux
authors: F
authors: F
authors: El-Moussawi
authors: P
authors: P
authors: Mariani-Kurkdjian
authors: E
authors: E
authors: Bingen
authors: O
authors: O
authors: Baud
authors: Y
authors: Y
authors: Aujard
mesh_terms: D000890:Anti-Infective Agents / Q000627:therapeutic use*; D002939:Ciprofloxacin / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D016920:Meningitis, Bacterial / Q000188:drug therapy*; D011552:Pseudomonas Infections / Q000188:drug therapy*
chemical_list: D000890:Anti-Infective Agents; D002939:Ciprofloxacin