Application of an in-situ thermo-polymerized porous polymer: creation of an on-column frit for a packed capillary HPLC column.
A 3-mm length of a porous monolithic polymer was prepared in a 0.32-mm inner-diameter fused-silica capillary by an in-situ thermo-polymerization method and used as an on-column frit for a packed capillary HPLC column. The on-column frit can resist high pressure up to 400 bar. A 5-microm packing material was packed in the capillary with the on-column frit by a slurry method. At pressure driving mode, separation of samples was performed using the capillary HPLC column. The in-situ frit preparation method has the advantages of easy preparation, easy control of the location of the frit and a mild preparing reaction condition.
Ma
Jiping
J
Institute of Environment & Municipal Engineering, Qingdao Technological University, P. R. China. majiping2001@yahoo.com
Ding
Mingyu
M
Xu
Yan
Y
Chen
Lingxin
L