title: [Diffuse primary fat replacement of the pancreas: an unusual cause of steatorrhea].
abstract: Diffuse and primitive fat replacement of the exocrine pancreas is a rare cause of exocrine pancreatic insufficiency in adults. We report two adult patients with chronic diarrhoea and steatorrhea whose morphologic abnormalities revealed diffuse fat replacement of the pancreas. Tomodensitometry detected diffuse characteristic abnormalities with fat intermixed with normal pancreatic lobules or a "vanishing pancreas". In one patient, magnetic resonance imaging and echo-endoscopy suggested abnormalities. Administration of pancreatic extracts improved symptoms.
authors: Service de Gastroentérologie, Hôpital Saint-Louis, 75010 Paris. alainjean.aubert@wanadoo.fr
authors: Alain
authors: A
authors: Aubert
authors: Jean-Marc
authors: JM
authors: Gornet
authors: Pascal
authors: P
authors: Hammel
authors: Philippe
authors: P
authors: Lévy
authors: Dermot
authors: D
authors: O'Toole
authors: Philippe
authors: P
authors: Ruszniewski
authors: Robert
authors: R
authors: Modigliani
authors: Marc
authors: M
authors: Lémann
mesh_terms: D000273:Adipose Tissue / Q000473:pathology; D000328:Adult; D000368:Aged; D003937:Diagnosis, Differential; D019160:Endosonography; D010188:Exocrine Pancreatic Insufficiency / Q000209:etiology; D005260:Female; D006801:Humans; D008068:Lipomatosis / Q000150:complications; D008279:Magnetic Resonance Imaging; D008297:Male; D010182:Pancreatic Diseases / Q000150:complications*; D045602:Steatorrhea / Q000209:etiology*; D014057:Tomography, X-Ray Computed