[Hepatitis c virus and type 2 diabetes mellitus].
OBJECTIVE
In literature there are many reports on hepatitis C virus (HCV) and type 2 diabetes mellitus association. However, many authors have proved this association in anti-HCV positive patients affected by cirrhosis. Thus, type 2 diabetes mellitus has been associated to cirrhosis rather than to HCV.


METHODS
We wanted to verify the type 2 diabetes mellitus prevalence in 3 606 anti-HCV positive patients both cirrhotic and noncirrhotic. The results obtained have been compared with those of 1 053 HBsAg positive patients. All the patients were hospitalised for the first time in our institute between January 1991 and December 2003.


RESULTS
Type 2 diabetes mellitus is more frequently associated to cirrhotic rather than to noncirrhotic patients, but between the 2 groups of patients (anti-HCV and HBsAg positive) HCV increases type 2 diabetes mellitus association significantly.


CONCLUSIONS
Hepatic cirrhosis and HCV make easier the onset of type 2 diabetes mellitus.
Guglielmi
V
V
Unità Operativa Complessa di Gastroenterologia ed Endoscopia Digestiva, IRCCS S. De Bellis, Castellana Grotte, BA, Italy. vitantonioguglielmi@tiscali.it
Tutino
M
M
Guerra
V
V
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016009:Chi-Square Distribution; D003924:Diabetes Mellitus, Type 2 / Q000453:epidemiology / Q000821:virology*; D005260:Female; D006509:Hepatitis B / Q000150:complications*; D006514:Hepatitis B Surface Antigens / Q000097:blood; D006526:Hepatitis C / Q000150:complications*; D006801:Humans; D008103:Liver Cirrhosis / Q000150:complications*; D008297:Male; D008875:Middle Aged; D015995:Prevalence
D006514:Hepatitis B Surface Antigens