title: Study of the oral microbial flora in patients with renal disease.
abstract: OBJECTIVE
  The aim of this study is to bacteriologically investigate the oral environment in patients with renal disease and thereby reveal their influence on both caries and periodontal diseases.
  
  
  METHODS
  The authors compared oral microbial flora between patients with renal disease (non-haemodialysis: n = 40, haemodialysis: n = 41) and healthy people (n = 62), and also between haemodialysis patients and non-haemodialysis patients in the disease group. Cariogenic bacteria were identified according to Dentocult System, whereas periodontal bacteria were identified using the polymerase chain reaction method.
  
  
  RESULTS
  When comparing between patients with renal disease and healthy people, the detected number of cariogenic bacteria and the detection rates of the periodontal bacteria in the patients with renal disease were significantly higher than in healthy people (P < 0.05). When comparing the patients on haemodialysis with those not receiving it, no significant differences in the detected number of cariogenic bacteria were observed. However, the detection rates of periodontal bacteria were lower in patients on haemodialysis (P < 0.05).
  
  
  CONCLUSIONS
  The findings suggest that patients with renal disease tend to have a high risk of dental caries and periodontal disease than the control.
authors: Sections of Dentistry for Persons with Disabilities, Tokyo Medical and Dental University, Tokyo 113-8549, Japan. yohedpd@tmd.ac.jp
authors: Yohei
authors: Y
authors: Takeuchi
authors: Hiroyuki
authors: H
authors: Ishikawa
authors: Minoru
authors: M
authors: Inada
authors: Osamu
authors: O
authors: Shinozuka
authors: Makoto
authors: M
authors: Umeda
authors: Tsuneyoshi
authors: T
authors: Yamazaki
authors: Momono
authors: M
authors: Yoshikawa
authors: Sei
authors: S
authors: Sasaki
mesh_terms: D000328:Adult; D000368:Aged; D003731:Dental Caries / Q000382:microbiology* / Q000503:physiopathology; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007674:Kidney Diseases / Q000382:microbiology* / Q000503:physiopathology / Q000628:therapy; D008875:Middle Aged; D009055:Mouth / Q000382:microbiology*; D010510:Periodontal Diseases / Q000382:microbiology* / Q000503:physiopathology; D006435:Renal Dialysis; D018570:Risk Assessment; D012463:Saliva / Q000737:chemistry; D012472:Salivation