title: Bis(diphenylphosphino)acetonitrile: synthesis, ligand properties and application in catalytic carbon-carbon coupling.
abstract: Treatment of acetonitrile (1 equiv.) with n-butyllithium (0.95 equiv.) followed by chlorodiphenylphosphine (0.95 equiv.) under optimised reaction conditions gave a ca. 60% yield of bis(diphenylphosphino)acetonitrile (dppmCN, 1). The bidentate ligand was employed in the synthesis of the four-membered chelate metal complexes (dppmCN)MCl(2) [M = Pd (6a), Pt (6b)] and (dppmCN)RuCp*(Cl) (7). A very active catalyst for bromobenzene/phenylboronic acid Suzuki-Miyaura coupling was in situ generated by treatment of Pd(OAc)(2) with bis(diphenylphosphino)acetonitrile [TOF (1 h) >600000].
authors: Organisch-Chemisches Institut der Universität Münster, Corrensstrasse 40, 48149, Münster, Germany.
authors: Leonie
authors: L
authors: Braun
authors: Patrick
authors: P
authors: Liptau
authors: Gerald
authors: G
authors: Kehr
authors: Juri
authors: J
authors: Ugolotti
authors: Roland
authors: R
authors: Fröhlich
authors: Gerhard
authors: G
authors: Erker