The use of a [4 + 2] cycloaddition reaction for the preparation of a series of 'tethered' Ru(II)-diamine and aminoalcohol complexes.
A series of catalysts have been prepared for use in the asymmetric transfer hydrogenation of ketones. The complexes were prepared using a [4 + 2] cycloaddition reaction at a key step in the reaction sequence. This provides a means for the synthesis of catalysts with modifications at specific sites.
Cheung
Fung Kei
FK
The Department of Chemistry, The University of Warwick, Coventry, UKCV4 7AL. m.wills@warwick.ac.uk.
Hayes
Aidan M
AM
Morris
David J
DJ
Wills
Martin
M
D000605:Amino Alcohols / Q000737:chemistry*; D002384:Catalysis; D003500:Cyclization; D003959:Diamines / Q000737:chemistry*; D006865:Hydrogenation; D007659:Ketones / Q000138:chemical synthesis / Q000737:chemistry; D008968:Molecular Conformation; D009942:Organometallic Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D012428:Ruthenium / Q000737:chemistry*; D013237:Stereoisomerism
D000605:Amino Alcohols; D003959:Diamines; D007659:Ketones; D009942:Organometallic Compounds; D012428:Ruthenium