[Serum serotonin level in patients with depression and panic attacks].
Serum serotonin level (SSL) was studied using ELISA method in 21 patients with depression associated with panic attacks (PA) and 15 non-depressed patients (8--with PA, 7--with the autonomous nervous system dysfunction). The authors found significant positive correlation between increased SSL and severity of depression, according to BDI (r = 0.82, r < 0.05). There was no correlation with other signs of the disease (anxiety, autonomous nervous system parameters). SSL in control group was about 72.6 +/- 10.06 ng/ml, in mild depressed patients--203.41 +/- 26.47 ng/ml, in severe depressed patients--438.58 +/- 36.31 ng/ml (P(1-2) < 0.001; P(2-3) < 0.001). It was proposed to use SSL for verification the depression severity.
Levada
O A
OA
Cherednichenko
N V
NV
Rybak
I R
IR
D000328:Adult; D003863:Depression / Q000097:blood* / Q000150:complications / Q000523:psychology; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D008297:Male; D009483:Neuropsychological Tests; D016584:Panic Disorder / Q000097:blood* / Q000150:complications / Q000523:psychology; D012701:Serotonin / Q000097:blood*
D012701:Serotonin