title: Copper-catalyzed highly efficient multicomponent reactions: synthesis of 2-(sulfonylimino)-4-(alkylimino)azetidine derivatives.
abstract: [reaction: see text] Under very mild conditions, functionalized 2-(sulfonylimino)-4-(alkylimino)azetidine derivatives were prepared in good to excellent yields via a copper-catalyzed multicomponent reaction of readily available terminal alkynes, sulfonyl azides, and carbodiimides without the assistance of a base. The mechanism may be through a [2 + 2] cycloaddition.
authors: College of Chemical Engineering and Materials Science and College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou 310014, People's Republic of China. xuxiaoliang@zjut.edu.cn
authors: Xiaoliang
authors: X
authors: Xu
authors: Dongping
authors: D
authors: Cheng
authors: Jinghua
authors: J
authors: Li
authors: Hongyun
authors: H
authors: Guo
authors: Jie
authors: J
authors: Yan
mesh_terms: D001384:Azetidines / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D018360:Crystallography, X-Ray; D007097:Imines / Q000138:chemical synthesis* / Q000737:chemistry; D007454:Iodides / Q000737:chemistry; D008958:Models, Molecular; D015394:Molecular Structure
chemical_list: D001384:Azetidines; D007097:Imines; D007454:Iodides; D003300:Copper; C073870:cuprous iodide