[Serum IL-12 level in mice infected with Trichinella spiralis].
Kunming mice were infected by feeding 150+/-5 larvae of Trichinella spiralis, established was also a normal control group. Blood was collected from the ophthalmic venous plexus respectively on 7 d, 21 d, 35 d and 49 d after infection and IL-12 in the serum was detected by ELISA. The level of IL-12 in serum decreased in groups of 7 d, 21 d, and 35 d, with a significant difference to the control (P<0.01). However, there was no significant difference between 49d group and control (P>0.05), suggesting that the serum IL-12 of the Trichinella spiralis-infected mice significantly decreased at the earlier stage but approached to normal at a later stage.
Wan
Qi-Hui
QH
Department of Parasitology, Zunyi Medical College, Zunyi 563003, China.
Wang
Jia-Li
JL
He
Li-Fang
LF
Liu
Hui
H
Zhang
Xi
X
D000818:Animals; D004797:Enzyme-Linked Immunosorbent Assay; D006790:Host-Parasite Interactions; D018664:Interleukin-12 / Q000097:blood*; D007814:Larva / Q000502:physiology; D051379:Mice; D008815:Mice, Inbred Strains; D017160:Trichinella spiralis / Q000502:physiology*; D014235:Trichinellosis / Q000097:blood* / Q000469:parasitology*
D018664:Interleukin-12