Deep brain stimulation and the role of the neuropsychologist.
Deep brain stimulation (DBS) now plays an important role in the treatment of Parkinson's disease, tremor, and dystonia. DBS may also have a role in the treatment of other disorders such as obsessive-compulsive disorder, Tourette's syndrome, and depression. The neuropsychologist plays a crucial role in patient selection, follow-up, and management of intra-operative and post-operative effects (Pillon, 2002; Saint-Cyr & Trepanier, 2000). There is now emerging evidence that DBS can induce mood, cognitive, and behavioral changes. These changes can have dramatic effects on patient outcome. There have been methodological problems with many of the studies of DBS on mood, cognition, and behavior. The neuropsychologist needs to be aware of these issues when following up patients, and constructing future studies. Additionally, this article will review all aspects of the DBS procedure that can result in mood, cognitive, and behavioral effects and what role(s) the neuropsychologist should play in screening and follow-up.
Okun
Michael S
MS
Department of Neurology, Movement Disorders Center, University of Florida, Gainesville, FL 32610, USA. okun@neurology.ufl.edu
Rodriguez
Ramon L
RL
Mikos
Ania
A
Miller
Kimberly
K
Kellison
Ida
I
Kirsch-Darrow
Lindsey
L
Wint
Dylan P
DP
Springer
Utaka
U
Fernandez
Hubert H
HH
Foote
Kelly D
KD
Crucian
Gregory
G
Bowers
Dawn
D
D001921:Brain / Q000503:physiopathology; D046690:Deep Brain Stimulation / Q000295:instrumentation*; D004421:Dystonia / Q000503:physiopathology / Q000628:therapy*; D004567:Electrodes, Implanted; D020329:Essential Tremor / Q000523:psychology / Q000628:therapy*; D006801:Humans; D009483:Neuropsychological Tests; D009484:Neuropsychology; D017063:Outcome Assessment, Health Care; D010300:Parkinson Disease / Q000523:psychology / Q000628:therapy*; D010348:Patient Care Team; D018579:Patient Selection; D013686:Telemetry / Q000295:instrumentation