Pernicious anemia.
Pernicious anemia is severe anemia most often affecting older adults, caused by failure of the stomach to absorb vitamin B12 and characterized by abnormally large red blood cells, gastrointestinal disturbances, and lesions of the spinal cord. Pernicious anemia is caused by a lack of intrinsic factor and could be an autoimmune disorder. The identification of various autoantibodies helps in the confirmation of the diagnosis and hence towards the patient management. In such patients, oral supplements or intramuscular injections of vitamin B12 are indicated.
Kumar
Vijay
V
IMMLO Diagnostics Inc., USA.
D000752:Anemia, Pernicious / Q000175:diagnosis* / Q000276:immunology / Q000503:physiopathology; D001323:Autoantibodies / Q000032:analysis*; D006801:Humans; D014481:United States
D001323:Autoantibodies