title: Aiolos: an ungrateful member of the Ikaros family.
abstract: Ikaros family members play an important role in hematopoietic development. Thompson et al. (2007) show that pre-BCR signaling induces Aiolos expression, which in turn suppresses the expression of the pre-BCR component lambda5 and eliminates the very structure that signaled its appearance.
authors: Division of Molecular Immunology, Medical Research Council National Institute for Medical Research, The Ridgeway, London NW7 1AA, UK. dkiouss@nimr.mrc.ac.uk
authors: Dimitris
authors: D
authors: Kioussis
mesh_terms: D000818:Animals; D001402:B-Lymphocytes / Q000276:immunology*; D051740:Ikaros Transcription Factor / Q000502:physiology*; D008213:Lymphocyte Activation / Q000235:genetics*; D051379:Mice; D015534:Trans-Activators / Q000235:genetics*
chemical_list: C491396:Ikzf3 protein, mouse; D015534:Trans-Activators; D051740:Ikaros Transcription Factor