A microwave enhanced cross-metathesis approach to peptidomimetics.
Functionalization of amino acid C- and N-termini with appropriate olefinic moieties allows for the generation of a peptidomimetic via a stereoselective cross-metathesis.
Morris
Thomas
T
University College London, Department of Chemistry, Christopher Ingold Laboratories, 20 Gordon Street, London, UK.
Sandham
David
D
Caddick
Stephen
S
D000475:Alkenes / Q000737:chemistry / Q000528:radiation effects*; D000596:Amino Acids / Q000138:chemical synthesis* / Q000737:chemistry / Q000528:radiation effects*; D008872:Microwaves; D008968:Molecular Conformation; D010455:Peptides / Q000138:chemical synthesis* / Q000737:chemistry / Q000528:radiation effects*; D013237:Stereoisomerism
D000475:Alkenes; D000596:Amino Acids; D010455:Peptides