Asymmetric hydrogenation of aryl ketones mediated by a copper catalyst.
[reaction: see text] A novel asymmetric hydrogenation protocol using a copper catalyst is reported. A Cu(I) complex in the presence of nonracemic BDPP hydrogenates aryl ketones with moderate to high enantioselectivity.
Shimizu
Hideo
H
Takasago International Corporation, Corporate Research and Development Division 1-4-11, Nishi-yawata, Hiratsuka City, Kanagawa 254-0073, Japan. hideo_shimizu@takasago.com
Igarashi
Daisuke
D
Kuriyama
Wataru
W
Yusa
Yukinori
Y
Sayo
Noboru
N
Saito
Takao
T