The effect of cinnamon on A1C among adolescents with type 1 diabetes.
OBJECTIVE
The purpose of this study was to determine the effect of cinnamon on glycemic control in adolescents with type 1 diabetes.


METHODS
Using a prospective, double-blind, placebo-controlled design, 72 adolescent type 1 diabetic subjects were treated in an outpatient setting with cinnamon (1 g/day) or an equivalent-appearing placebo for 90 days. A1C, total daily insulin intake, and adverse events were recorded and compared between groups.


RESULTS
There were no significant differences in final A1C (8.8 vs. 8.7, P = 0.88), change in A1C (0.3 vs. 0.0, P = 0.13), total daily insulin intake, or number of hypoglycemic episodes between the cinnamon and placebo arms.


CONCLUSIONS
Cinnamon is not effective for improving glycemic control in adolescents with type 1 diabetes.
Altschuler
Justin A
JA
Department of Biological Sciences, Dartmouth College, Hanover, New Hampshire, USA.
Casella
Samuel J
SJ
MacKenzie
Todd A
TA
Curtis
Kevin M
KM
D000293:Adolescent; D002935:Cinnamomum zeylanicum; D003922:Diabetes Mellitus, Type 1 / Q000097:blood* / Q000188:drug therapy; D004311:Double-Blind Method; D005260:Female; D006442:Glycated Hemoglobin / Q000378:metabolism*; D006801:Humans; D007004:Hypoglycemic Agents / Q000627:therapeutic use; D007328:Insulin / Q000627:therapeutic use; D007332:Insulin Infusion Systems; D008297:Male; D008517:Phytotherapy; D011446:Prospective Studies
D006442:Glycated Hemoglobin; D007004:Hypoglycemic Agents; D007328:Insulin