Management of vestibular schwannomas in young patients-comparison of clinical features and outcome with adult patients.
OBJECTIVE
Vestibular schwannomas (VS) in young patients are rare. They are regarded to have different biological characteristics. Our objective is to analyze a series of such patients, with respect to their clinical presentation, treatment, and outcome and to compare the results to a matched series of adult patients.


METHODS
Retrospective analysis of 20 patients under 21 years of age. All patients underwent surgery via the retrosigmoid approach. The analysis included: age, gender, tumor size, clinical, and neurological pre- and postoperative status including cochlear and facial nerve function, and complications. Statistical comparison of the young patient's data with a series of 200 adult patients previously published by the authors.


CONCLUSIONS
The current study demonstrates that the outcome after surgical management in patients harboring VS does not show any significant difference between young and adult patients.
Mirzayan
M Javad
MJ
Department of Neurosurgery, Medizinische Hchschule Hannover, Hannover, Germany.
Gerganov
Venelin M
VM
Lüdemann
Wolf
W
Oi
Shizuo
S
Samii
Madjid
M
Samii
Amir
A
D000293:Adolescent; D000328:Adult; D003056:Cochlear Nerve / Q000502:physiology; D004428:Ear Neoplasms / Q000473:pathology / Q000601:surgery*; D004594:Electrophysiology; D005154:Facial Nerve / Q000502:physiology; D005158:Facial Paralysis / Q000209:etiology / Q000503:physiopathology; D005260:Female; D034381:Hearing Loss / Q000209:etiology; D006801:Humans; D007223:Infant; D017567:Karnofsky Performance Status; D008279:Magnetic Resonance Imaging; D008297:Male; D009464:Neuroma, Acoustic / Q000473:pathology / Q000601:surgery*; D019635:Neurosurgical Procedures; D011183:Postoperative Complications / Q000453:epidemiology / Q000503:physiopathology; D016896:Treatment Outcome; D014722:Vestibule, Labyrinth