title: Large primary meningeal melanoma in an adult patient with neurocutaneous melanosis.
abstract: Neurocutaneous melanosis is often associated with melanoma of the central nervous system. Due to the inconspicuously looking cutaneous melanosis additional examinations are often not performed. We describe a patient with cutaneous melanosis who presented with neurological symptoms due to a large primary meningeal melanoma. The diagnosis of neurocutaneous melanosis was made. This case is an illustration of melanoma development in the central nervous system in a patient with cutaneous melanosis. This phenomenon should be kept in mind when observing patients with such skin lesions, even if they are of minor extent.
authors: Department of Dermatology and Allergy, Skin Cancer Center, Charité-Universitätsmedizin Berlin, Charitéplatz 1, 10117 Berlin, Germany.
authors: Felix
authors: F
authors: Kiecker
authors: Maja A
authors: MA
authors: Hofmann
authors: Heike
authors: H
authors: Audring
authors: Aeilke
authors: A
authors: Brenner
authors: Christine
authors: C
authors: Labitzke
authors: Wolfram
authors: W
authors: Sterry
authors: Uwe
authors: U
authors: Trefzer
mesh_terms: D000328:Adult; D001929:Brain Edema / Q000175:diagnosis; D003713:Dendritic Cells / Q000473:pathology; D020405:Dermis / Q000473:pathology; D004388:Dura Mater / Q000473:pathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008545:Melanoma / Q000175:diagnosis* / Q000473:pathology; D008548:Melanosis / Q000175:diagnosis* / Q000473:pathology; D008577:Meningeal Neoplasms / Q000175:diagnosis* / Q000473:pathology; D020752:Neurocutaneous Syndromes / Q000175:diagnosis* / Q000473:pathology; D009460:Neurologic Examination; D014057:Tomography, X-Ray Computed