title: Atypical masticatory muscle myositis in three cavalier King Charles spaniel littermates.
abstract: This case report describes a novel manifestation of the immune-mediated disease, masticatory muscle myositis. Clinical signs, including difficulty in opening the mouth (trismus), were seen in three of four 12-week-old cavalier King Charles spaniel littermates. Diagnosis was established by 2M immunohistochemistry, supported by characteristic histopathological changes in affected temporal muscle. Treatment using corticosteroids at immune-modifying doses resulted in resolution of clinical signs in all the affected animals. Masticatory muscle myositis should be considered as a differential diagnosis in groups of young dogs with clinical signs of myositis localised to the head.
authors: Taverham Veterinary Practice, Fakenham Road, Taverham, Norfolk NR8 6QW, UK.
authors: G D C
authors: GD
authors: Pitcher
authors: C N
authors: CN
authors: Hahn
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use*; D000818:Animals; D003937:Diagnosis, Differential; D004283:Dog Diseases / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D004285:Dogs; D007150:Immunohistochemistry / Q000662:veterinary; D008297:Male; D008410:Masticatory Muscles / Q000473:pathology*; D009220:Myositis / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology / Q000662:veterinary*; D016896:Treatment Outcome; D014313:Trismus / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology / Q000662:veterinary*
chemical_list: D000305:Adrenal Cortex Hormones