Study of the buffering capacity, pH and salivary flow rate in type 2 well-controlled and poorly controlled diabetic patients.
OBJECTIVE
This study measured the flow rate, pH and buffering capacity of saliva from well- and poorly metabolically controlled Type 2 diabetic patients in three cities of the southern part of Brazil, compared with healthy individuals from the same cities.


METHODS
Whole saliva was collected by mechanical stimulation and buffering capacity and glucose level were measured. Blood was collected after 12 hours fasting and glucose and glycosylated haemoglobin concentrations were determined. The data were analysed by one-way ANOVA and Student-Newman-Keuls (alpha= 0.05).


RESULTS
The flow rate was lower in the Type 2 diabetic patients, regardless of whether they were well or poorly metabolically controlled, compared with healthy individuals (p < 0.05). Salivary glucose concentration was higher in both diabetic patient groups, i.e. well and poorly metabolically controlled, than in the control (p < 0.05).


CONCLUSIONS
The metabolic control of hyperglycaemia was not sufficient to improve the salivary flow rate or the salivary glucose concentration.
Bernardi
Maria José
MJ
University of Oeste de Santa Catarina, Campus Joaçaba, SC, Brazil.
Reis
Alessandra
A
Loguercio
Alessandro Dourado
AD
Kehrig
Ruth
R
Leite
Mariana Ferreira
MF
Nicolau
José
J
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001786:Blood Glucose / Q000032:analysis; D002021:Buffers; D003924:Diabetes Mellitus, Type 2 / Q000097:blood / Q000503:physiopathology* / Q000517:prevention & control; D005215:Fasting; D005260:Female; D005947:Glucose / Q000032:analysis; D006442:Glycated Hemoglobin / Q000032:analysis; D006801:Humans; D006863:Hydrogen-Ion Concentration; D006943:Hyperglycemia / Q000097:blood / Q000517:prevention & control; D008297:Male; D008875:Middle Aged; D012463:Saliva / Q000737:chemistry / Q000378:metabolism / Q000502:physiology*; D012636:Secretory Rate / Q000502:physiology; D014987:Xerostomia / Q000503:physiopathology
D001786:Blood Glucose; D002021:Buffers; D005947:Glucose; D006442:Glycated Hemoglobin