Hereditary spastic paraplegia with a thin corpus callosum.
We report a 15-year-old boy with autosomal recessive complicated hereditary spastic paraplegia with a thin corpus callosum (HSP-TCC). The involvement of the corpus callosum was characteristic with the genu and body predominantly affected with relative sparing of the splenium. HSP-TCC is being increasingly recognized over a wider geographical area than earlier believed. We now report a case of HSP-TCC from the Indian subcontinent.
Somasundaram
Sivaraman
S
Department of Imaging Sciences and Interventional Radiology, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum, India.
Raghavendra
Seetharam
S
Singh
Atampreet
A
Kesavadas
Chandrasekharan
C
Nair
Muraleedharan
M
D000293:Adolescent; D061085:Agenesis of Corpus Callosum; D003241:Consanguinity; D003337:Corpus Callosum / Q000473:pathology; D005808:Genes, Recessive; D006801:Humans; D007194:India; D008607:Intellectual Disability / Q000150:complications; D008279:Magnetic Resonance Imaging; D008297:Male; D009421:Nervous System Malformations / Q000150:complications / Q000175:diagnosis*; D015419:Spastic Paraplegia, Hereditary / Q000150:complications / Q000175:diagnosis*