title: Mineral deficiency in patients who have undergone gastrectomy.
abstract: OBJECTIVE
  We investigated the nature of nutritional deficiencies that arose in gastrectomy patients by comparing mineral absorption in patients with total and subtotal gastrectomies before and after operation.
  
  
  METHODS
  Levels of nutritional, micro, and toxic minerals were measured in a subject group of 20 patients with gastric cancer. Patients were grouped according to total versus subtotal gastrectomy. Hair tissue was collected 3 mo before and after operation from each patient. Tissue was analyzed by atomic absorption spectroscopy for levels of various minerals. Mineral ratios were computed to display changes in mineral levels, and results were statistically analyzed with SPSS 10.0 to obtain a measurement distribution. The t test was used to determine any significant difference between patients before and after operation.
  
  
  RESULTS
  In the preoperation test, sodium, potassium and iron levels were higher than normal, whereas boron and molybdenum levels were lower than normal. Although sodium levels decreased significantly after surgery, molybdenum, cadmium, and lead levels increased significantly. Potassium decreased slightly in the subtotal gastrectomy group, but increased significantly in the total gastrectomy group. However, there was no change between before and after surgery for most minerals.
  
  
  CONCLUSIONS
  In the short term, gastrectomy does not seem to affect the levels of most minerals in the body. However, changes in sodium levels indicate that gastrectomy affects sodium absorbency in gastric cancer patients. Potassium levels increased significantly in patients who received total gastrectomies; this may also be an area that nutritional treatment should focus on.
authors: Department of Surgery, Yonsei University, College of Medicine, Seoul, Republic of Korea.
authors: Irene
authors: I
authors: Kang
authors: Yu Suk
authors: YS
authors: Kim
authors: Choongbai
authors: C
authors: Kim
mesh_terms: D000328:Adult; D000368:Aged; D001895:Boron / Q000032:analysis / Q000493:pharmacokinetics; D002118:Calcium / Q000032:analysis / Q000493:pharmacokinetics; D003677:Deficiency Diseases / Q000453:epidemiology* / Q000209:etiology / Q000517:prevention & control; D005260:Female; D005743:Gastrectomy / Q000009:adverse effects*; D006197:Hair / Q000737:chemistry*; D006801:Humans; D007408:Intestinal Absorption; D007501:Iron / Q000032:analysis / Q000493:pharmacokinetics; D007854:Lead / Q000032:analysis / Q000493:pharmacokinetics; D008297:Male; D008875:Middle Aged; D008903:Minerals / Q000032:analysis* / Q000493:pharmacokinetics*; D008982:Molybdenum / Q000032:analysis / Q000493:pharmacokinetics; D009752:Nutritional Status; D018529:Nutritional Support; D011188:Potassium / Q000032:analysis / Q000493:pharmacokinetics; D012964:Sodium / Q000032:analysis / Q000493:pharmacokinetics; D013274:Stomach Neoplasms / Q000378:metabolism / Q000601:surgery*
chemical_list: D008903:Minerals; D007854:Lead; D008982:Molybdenum; D012964:Sodium; D007501:Iron; D001895:Boron; D011188:Potassium; D002118:Calcium