A novel approach to central venous catheter thrombosis in a patient with cystic fibrosis.
Catheter directed thrombolysis has been described as a treatment for large pulmonary emboli resistant to systemic therapy [Kelly P, Carroll N, Grant C, Barrett C, Kocka V. Successful treatment of massive pulmonary embolism with prolonged catheter-directed thrombolysis. Heart Vessels 2006;21:124?6]. We now describe a case in which local catheter directed thrombolysis, via a peripherally inserted central catheter (PICC), was used to treat a large thrombus surrounding the tip of an indwelling central venous line that was causing superior vena cava obstruction (SVCO), in a patient with cystic fibrosis.
Hull
J H K
JH
Knight Centre for Cystic Fibrosis, Frimley Park Hospital NHS Foundation Trust, Camberley, Surrey GU16 7UJ, UK.
Tucker
W
W
Hatrick
A G
AG
Knight
R K
RK
Ho
T B L
TB
D000328:Adult; D002405:Catheterization, Central Venous / Q000009:adverse effects*; D003550:Cystic Fibrosis / Q000150:complications*; D005260:Female; D005343:Fibrinolytic Agents / Q000627:therapeutic use; D006493:Heparin / Q000627:therapeutic use; D006801:Humans; D015912:Thrombolytic Therapy / Q000379:methods*; D013927:Thrombosis / Q000188:drug therapy* / Q000209:etiology*; D010959:Tissue Plasminogen Activator / Q000627:therapeutic use
D005343:Fibrinolytic Agents; D006493:Heparin; D010959:Tissue Plasminogen Activator