title: Ciliary ultrastructure in two sisters with Kartagener's syndrome.
abstract: Kartagener's syndrome (KS) is a clinical variant of primary ciliary dyskinesia involving situs inversus associated with chronic airway infections. We studied two sisters; the elder one had dextrocardia and scoliosis, and the younger one had situs inversus of the lung, liver, and stomach as well as dextrocardia. Both patients had chronic sinusitis and chronic bronchitis with bronchiectasis. In both cases, the ciliary defect associated with this syndrome is the absence of inner dynein arms.
authors: Division of Morphological Science, Biomedical Research Center, Saitama Medical University, 38 Moroyama, Iruma-gun, Saitama 350-0495, Japan.
authors: Kayoko
authors: K
authors: Tanaka
authors: Akihisa
authors: A
authors: Sutani
authors: Yuka
authors: Y
authors: Uchida
authors: Yoshihiko
authors: Y
authors: Shimizu
authors: Michio
authors: M
authors: Shimizu
authors: Masumi
authors: M
authors: Akita
mesh_terms: D000328:Adult; D001987:Bronchiectasis / Q000473:pathology; D029481:Bronchitis, Chronic / Q000473:pathology; D002923:Cilia / Q000648:ultrastructure*; D003914:Dextrocardia / Q000473:pathology; D005260:Female; D006801:Humans; D007619:Kartagener Syndrome / Q000473:pathology*; D008099:Liver / Q000473:pathology; D008168:Lung / Q000473:pathology / Q000648:ultrastructure; D046529:Microscopy, Electron, Transmission; D020545:Respiratory Mucosa / Q000473:pathology / Q000648:ultrastructure*; D012600:Scoliosis / Q000473:pathology; D035781:Siblings; D012852:Sinusitis / Q000473:pathology; D012857:Situs Inversus / Q000473:pathology; D013270:Stomach / Q000473:pathology