Acanthamoeba keratitis related to orthokeratology.
OBJECTIVE
To report four cases of Acanthamoeba keratitis related to the overnight wearing of orthokeratology lenses.


METHODS
Four patients had histories of overnight wearing of orthokeratology lenses when they presented with corneal ulcers. They had used a contact lens care system irregularly with tap water.


RESULTS
The organism isolated by corneal scraping was Acanthamoeba. The patients were treated with polyhexamethylene biguanide (PHMB) and chlorhexidine, resulting in a resolution of ocular inflammation.


CONCLUSIONS
The risk of Acanthamoeba keratitis as a potential complication of overnight orthokeratology should be considered, especially in patients with over one-year duration of contact lens wearing. Careful contact lens management is needed and tap-water rinsing should be eliminated from the lens care regimen.
Lee
Ji-Eun
JE
Department of Ophthalmology, College of Medicine, Pusan National University, 1-10, Ami-Dong, Seo-Ku, Pusan 602-739, Korea.
Hahn
Tae Won
TW
Oum
Boo Sup
BS
Choi
Hee Young
HY
Yu
Hak Sun
HS
Lee
Jong Soo
JS
D015823:Acanthamoeba Keratitis / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology / Q000503:physiopathology; D000293:Adolescent; D000891:Anti-Infective Agents, Local / Q000627:therapeutic use; D001645:Biguanides / Q000627:therapeutic use; D002710:Chlorhexidine / Q000627:therapeutic use; D002940:Circadian Rhythm; D003261:Contact Lenses / Q000009:adverse effects*; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D008297:Male; D014792:Visual Acuity
D000891:Anti-Infective Agents, Local; D001645:Biguanides; C031233:polihexanide; D002710:Chlorhexidine