title: [Cytomegalovirus and cryptogenic inflammatory bowel disease].
abstract: CMV infection has been reported in association with some flares of IBD. Its prevalence varies with the method of diagnosis and the severity of IBD. Although the link between CMV and IBD is not clear, the immunomodulator properties of the virus may play a role in the evolution of IBD. Besides the necessity of immunosuppression to treat IBD, inflammation per se can maintain in situ viral replication. Antiviral treatment can be useful in some situations. New molecular methods will permit earlier and more sensitive diagnosis of CMV infection and a better evaluation of treatment efficacy.
authors: Département d'Hépato-Gastroentérologie, CHU de Grenoble, Cedex. JPofelski@chu-grenoble.fr
authors: Joanna
authors: J
authors: Pofelski
authors: Frédéric
authors: F
authors: Heluwaert
authors: Xavier
authors: X
authors: Roblin
authors: Patrice
authors: P
authors: Morand
authors: Bénédicte
authors: B
authors: Gratacap
authors: Emmanuel
authors: E
authors: Germain
authors: Jean-Paul
authors: JP
authors: Brion
authors: Caroline
authors: C
authors: Salon
authors: Bruno
authors: B
authors: Bonaz
mesh_terms: D000998:Antiviral Agents / Q000627:therapeutic use; D003587:Cytomegalovirus / Q000276:immunology; D003586:Cytomegalovirus Infections / Q000175:diagnosis* / Q000188:drug therapy; D006801:Humans; D007155:Immunologic Factors / Q000276:immunology; D015212:Inflammatory Bowel Diseases / Q000188:drug therapy / Q000821:virology*; D014779:Virus Replication / Q000502:physiology
chemical_list: D000998:Antiviral Agents; D007155:Immunologic Factors