title: Long-term evaluation of erythema and pigmentation induced by ultraviolet radiations of different wavelengths.
abstract: OBJECTIVE
  Although multiple studies have been reported about the biological effects of ultraviolet (UV) radiations, the comparative and long-term reactions of human skin by several different UV-wavebands were not reported. The aim of this study was to investigate a time course of erythema and pigmentation induced by UVA 1, broad-band UVA (BBUVA), narrow-band UVB (NBUVB) and broad-band UVB (BBUVB).
  
  
  METHODS
  Ten volunteers participated in this study for 6 months. Four skin areas, from the back of each subject, were irradiated with two minimal erythema dose (MED) of four different UV wavelengths corresponding to UVA 1, BBUVA, NBUVB and BBUVB. Skin color changes were evaluated by visual scoring and values were converted into the L*a*b color system.
  
  
  RESULTS
  For both UVA 1 and BBUVA, erythema and pigmentation were most pronounced immediately and 1 h after exposure. Thereafter, erythema rapidly diminished but pigmentation persisted throughout the study. For both NBUVB and BBUVB, test areas reacted with erythema of maximum intensity at 1 and 2 days, respectively. A maximum tanning was reached at 3-6 days for NBUVB and 4-7 days for BBUVB, and the return toward the original color point was at 1 and 3 months, respectively. No significant difference was found in visual and colorimetric evaluation for the time course of skin color changes.
  
  
  CONCLUSIONS
  Two MED of UVA produced far prolonged erythema and pigmentation than UVB. For UVA, UVA 1 and BBUVA showed similar intensity and time course of skin reaction. For UVB, erythema and pigmentation produced by NBUVB were milder in intensity and shorter in time course than those by BBUVB. These results would provide standard data on time courses and intensity of skin color changes by different UV wavelengths.
authors: Department of Dermatology, Kosin University College of Medicine, Busan, South Korea.
authors: K-S
authors: KS
authors: Suh
authors: H-J
authors: HJ
authors: Roh
authors: S-Y
authors: SY
authors: Choi
authors: Y-S
authors: YS
authors: Jeon
authors: K-S
authors: KS
authors: Doh
authors: J-H
authors: JH
authors: Bae
authors: S-T
authors: ST
authors: Kim
mesh_terms: D000328:Adult; D003124:Colorimetry; D004307:Dose-Response Relationship, Radiation; D004890:Erythema / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology*; D006801:Humans; D008297:Male; D011829:Radiation Dosage; D011832:Radiation Injuries / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology*; D012867:Skin / Q000503:physiopathology* / Q000528:radiation effects*; D012880:Skin Pigmentation / Q000528:radiation effects*; D013471:Sunburn / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology*; D014466:Ultraviolet Rays / Q000009:adverse effects*