Localization, quantification, and characterization of tuftelin in soft tissues.
Tuftelin was initially found in the developing and mature extracellular enamel. Here we describe our novel discovery of tuftelin cellular distribution (protein and mRNA) in six soft tissues. The expression levels of tuftelin mRNA were significantly higher in mouse kidney and testis, in which oxygen levels are hovering closely to hypoxia under normal conditions.
Leiser
Yoav
Y
Dental Research Laboratory, Institute of Dental Sciences, Hebrew University-Hadassah Faculty of Dental Medicine, Jerusalem, Israel.
Blumenfeld
Anat
A
Haze
Amir
A
Dafni
Leah
L
Taylor
Angela L
AL
Rosenfeld
Eli
E
Fermon
Eran
E
Gruenbaum-Cohen
Yael
Y
Shay
Boaz
B
Deutsch
Dan
D
D000818:Animals; D015153:Blotting, Western; D001923:Brain Chemistry; D015687:Cell Hypoxia; D003746:Dental Enamel Proteins / Q000032:analysis* / Q000235:genetics; D005123:Eye / Q000737:chemistry; D015870:Gene Expression; D007150:Immunohistochemistry; D017403:In Situ Hybridization; D007668:Kidney / Q000737:chemistry* / Q000502:physiology; D008099:Liver / Q000737:chemistry; D008168:Lung / Q000737:chemistry; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D018613:Microscopy, Confocal; D012333:RNA, Messenger / Q000032:analysis; D020133:Reverse Transcriptase Polymerase Chain Reaction; D013737:Testis / Q000737:chemistry* / Q000502:physiology; D015854:Up-Regulation
D003746:Dental Enamel Proteins; D012333:RNA, Messenger; C038456:tuftelin