[The advancement on mitochondrion of cryptosporidium].
Cryptosporidiosis is an important apicomplexan disease with medical and veterinary significance. There is still no effective drug for its control. Mitochondrion is an organelle which contains most protein and enzyme in eukaryotes, so the mitochondrion of Cryptosporidium may be a potential target of drugs. Recent studies provided evidence for a mitochondrial derived compartment in this parasite. But the organelle has some difference to that of other apicomplexan parasites. This organelle appears to lack its genome, and thus must be entirely dependent on nuclear-encoded proteins. This article reviews the evidence for the organelle in Cryptosporidium and its probable function.
Wang
Jin-Chan
JC
College of Animal Science and Veterinary Medicine, Henan Agricultural University, Zhengzhou 450002, China.
Zhang
Long-Xian
LX
Ning
Chang-Shen
CS
Jian
Fu-Chun
FC
Shao
Zhao-Xia
ZX
Shi
Tuan-Yuan
TY
D000818:Animals; D003458:Cryptosporidium / Q000378:metabolism / Q000502:physiology*; D008928:Mitochondria / Q000378:metabolism / Q000502:physiology*