title: Treatment of a patient with epidermodysplasia verruciformis carrying a novel EVER2 mutation with imiquimod.
abstract: Epidermodysplasia verruciformis (EV) is a rare disorder characterized by widespread human papillomavirus infection and malignant transformation. EV may be caused by mutations of the genes EVER1 or EVER2, which are located on the EV1 locus, 17q25. We describe a patient with EV and a novel homozygous gene mutation of EVER2 gene who was treated successfully with topical imiquimod.
authors: Medical School, University of Texas Southwestern Medical Center at Dallas, USA.
authors: Cindy
authors: C
authors: Berthelot
authors: Mary C
authors: MC
authors: Dickerson
authors: Peter
authors: P
authors: Rady
authors: Qin
authors: Q
authors: He
authors: Farhad
authors: F
authors: Niroomand
authors: Stephen K
authors: SK
authors: Tyring
authors: Amit G
authors: AG
authors: Pandya
mesh_terms: D000287:Administration, Topical; D000328:Adult; D000634:Aminoquinolines / Q000008:administration & dosage*; D000970:Antineoplastic Agents / Q000008:administration & dosage*; D002280:Basal Cell Carcinoma / Q000209:etiology / Q000473:pathology / Q000628:therapy; D002294:Carcinoma, Squamous Cell / Q000209:etiology / Q000473:pathology / Q000628:therapy; D004819:Epidermodysplasia Verruciformis / Q000150:complications / Q000235:genetics* / Q000628:therapy*; D006801:Humans; D000077271:Imiquimod; D008297:Male; D008565:Membrane Proteins / Q000235:genetics*; D009154:Mutation; D012878:Skin Neoplasms / Q000209:etiology* / Q000473:pathology / Q000628:therapy
chemical_list: D000634:Aminoquinolines; D000970:Antineoplastic Agents; D008565:Membrane Proteins; C470315:TMC8 protein, human; D000077271:Imiquimod