Massarilactones E-G, new metabolites from the endophytic fungus Coniothyrium sp., associated with the plant Artimisia maritima.
Three new massarilactones E-G (1-3) and the massarilactone acetonide (4) were isolated from the ethyl acetate extract of the endophytic fungus Coniothyrium sp., associated with the plant Artimisia maritima. Their structures were determined by analysis of the 1D and 2D NMR and mass spectroscopic data. The structure of massarilactones E (1) was confirmed by X-ray diffraction analysis, and its absolute configuration determined by the solid-state CD/TDDFT method.
Krohn
Karsten
K
Department of Chemistry, Universität Paderborn, 100 33098 Paderborn, Germany. k.krohn@uni-paderborn.de
Hussain
Hidayat
H
Flörke
Ulrich
U
Schulz
Barbara
B
Draeger
Siegfried
S
Pescitelli
Gennaro
G
Salvadori
Piero
P
Antus
Sándor
S
Kurtán
Tibor
T
D002626:Chemistry, Pharmaceutical / Q000379:methods*; D002855:Chromatography, Thin Layer; D004224:Diterpenes / Q000737:chemistry* / Q000302:isolation & purification; D005658:Fungi / Q000378:metabolism*; D007783:Lactones / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D009682:Magnetic Resonance Spectroscopy; D008956:Models, Chemical; D015394:Molecular Structure; D010944:Plants / Q000382:microbiology*; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet; D014961:X-Ray Diffraction
D004224:Diterpenes; D007783:Lactones; C522455:massarilactone E; C522456:massarilactone F; C522457:massarilactone G