Effect of insulin-glucose infusion on mortality following acute myocardial infarction in patients with diabetes: the diabetes and insulin-glucose infusion in acute myocardial infarction studies.
People with type 2 diabetes and other glucose abnormalities are very common among today's patients with acute coronary syndrome (ACS) and recent studies indicate that they still have an unfavorable prognosis compared to patients with normal glucose metabolism. In fact, they account for a substantial proportion of the residual morbidity and mortality in the ACS population. The common denominator seems to be an elevated blood glucose during the acute event and current evidence indicates that acute and long-term tight glucose control will improve the prognosis for this rapid growing patient population.
Malmberg
Klas
K
Karolinska Institutet, Stockholm, Sweden. klas.malmberg@ki.se
Rydén
Lars
L
D001786:Blood Glucose / Q000187:drug effects* / Q000378:metabolism; D003327:Coronary Disease / Q000097:blood / Q000401:mortality; D003924:Diabetes Mellitus, Type 2 / Q000097:blood / Q000188:drug therapy*; D005947:Glucose / Q000008:administration & dosage*; D006801:Humans; D007004:Hypoglycemic Agents / Q000008:administration & dosage*; D007262:Infusions, Intravenous; D007328:Insulin / Q000008:administration & dosage*; D009203:Myocardial Infarction / Q000097:blood / Q000401:mortality*; D016032:Randomized Controlled Trials as Topic
D001786:Blood Glucose; D007004:Hypoglycemic Agents; D007328:Insulin; D005947:Glucose