title: Callus of Securinega suffruticosa, a cell line accumulates dextro Securinega alkaloids.
abstract: Investigations on callus cultures of Securinega suffruticosa indicated that the cell line of S. suffruticosa callus was able to accumulate four known Securinega alkaloids with dextro rotation but not levo rotation as reported before: virosecurinine (1), viroallosecurinine (2), 14,15-dihydrovirosecurinine (3) and ent-phyllanthidine (4). Time course studies on the growth of callus cultures were carried out. The effects of different plant growth regulators, sucrose concentrations on callus growth and virosecurinine production were also reported.
authors: Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, China.
authors: Wei
authors: W
authors: Yuan
authors: Ping
authors: P
authors: Zhu
authors: Kedi
authors: K
authors: Cheng
authors: Chao
authors: C
authors: Meng
authors: Lin
authors: L
authors: Ma
authors: Feng
authors: F
authors: Wu
authors: Huixin
authors: H
authors: Zhu
mesh_terms: D000470:Alkaloids / Q000032:analysis / Q000096:biosynthesis / Q000737:chemistry / Q000378:metabolism*; D001381:Azepines / Q000032:analysis; D002455:Cell Division / Q000502:physiology; D002460:Cell Line; D002851:Chromatography, High Pressure Liquid; D003470:Culture Media; D003583:Cytokinins / Q000494:pharmacology; D019665:Euphorbiaceae / Q000737:chemistry* / Q000166:cytology / Q000378:metabolism*; D006576:Heterocyclic Compounds, 4 or More Rings / Q000032:analysis; D006572:Heterocyclic Compounds, Bridged-Ring; D007210:Indoleacetic Acids / Q000494:pharmacology; D007783:Lactones / Q000032:analysis; D009682:Magnetic Resonance Spectroscopy; D010880:Piperidines / Q000032:analysis; D018547:Plant Stems / Q000166:cytology / Q000378:metabolism; D013237:Stereoisomerism
chemical_list: D000470:Alkaloids; D001381:Azepines; D003470:Culture Media; D003583:Cytokinins; D006576:Heterocyclic Compounds, 4 or More Rings; D006572:Heterocyclic Compounds, Bridged-Ring; D007210:Indoleacetic Acids; D007783:Lactones; D010880:Piperidines; C012607:virosecurinine; C000785:securinine