Volume-targeted ventilation of newborns.
Traditional management of neonatal respiratory failure has been accomplished with mechanical ventilation delivered by time-cycled, pressure-limited techniques. Although easy to use, this modality results in the delivery of tidal volumes that vary according to pulmonary compliance. In contrast, volume-targeted ventilation delivers a selected tidal volume at variable peak inspiratory pressure, resulting in consistent tidal volume delivery, even in the face of changing compliance. This article reviews salient features of volume-targeted ventilation and a review of the evidence base.
Singh
Jaideep
J
James Cook University Hospital, Marton Road, Middlesbrough, TS4 3BW, UK.
Sinha
Sunil K
SK
Donn
Steven M
SM
D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D008170:Lung Compliance; D012123:Pulmonary Ventilation / Q000502:physiology*; D012121:Respiration, Artificial / Q000379:methods*; D012127:Respiratory Distress Syndrome, Newborn / Q000628:therapy*