title: Primary duodenal neoplasms: a retrospective clinico-pathological analysis.
abstract: OBJECTIVE
  To analyze the clinico-pathological spectrum of primary duodenal neoplasms.
  
  
  METHODS
  A total of 55 primary duodenal neoplasms reported in the last 10 years after excluding ampullary and periampullary tumors were included in the study. Clinical details were noted and routine hematoxylin and eosin stained paraffin sections were studied for histological subtyping of the tumors.
  
  
  RESULTS
  On histopathological examination primary duodenal neoplasms were categorized as: epithelial tumor in 27 cases (49.0%) including 10 cases of adenoma, 15 cases of adenocarcinoma, and 2 cases of Brunner gland adenoma; mesenchymal tumor in 9 cases (16.3%) consisting of 4 cases of gastrointestinal stromal tumor, 4 cases of smooth muscle tumor and I case of neurofibroma; lymphoproliferative tumor in 12 cases (21.8%), and neuroendocrine tumor in 7 cases (12.7%).
  
  
  CONCLUSIONS
  Although non-ampullary/periampullary duodenal adenocarcinomas are rare, they constitute the largest group. Histopathological examination of primary duodenal tumors is important for correct histological subtyping.
authors: Department of Histopathology, Post Graduate Institute of Medical Sciences and Research, Chandigarh 160012, India. docaman5@hotmail.com
authors: Amanjit
authors: A
authors: Bal
authors: Kusum
authors: K
authors: Joshi
authors: Kim
authors: K
authors: Vaiphei
authors: J D
authors: JD
authors: Wig
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis / Q000473:pathology; D000236:Adenoma / Q000175:diagnosis / Q000473:pathology; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D004379:Duodenal Neoplasms / Q000175:diagnosis / Q000473:pathology*; D005260:Female; D005770:Gastrointestinal Neoplasms / Q000175:diagnosis / Q000473:pathology; D046152:Gastrointestinal Stromal Tumors / Q000175:diagnosis / Q000473:pathology*; D006801:Humans; D008228:Lymphoma, Non-Hodgkin / Q000175:diagnosis / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009375:Neoplasms, Glandular and Epithelial / Q000175:diagnosis / Q000473:pathology*; D018358:Neuroendocrine Tumors / Q000175:diagnosis / Q000473:pathology*; D009455:Neurofibroma / Q000175:diagnosis / Q000473:pathology; D012189:Retrospective Studies; D018235:Smooth Muscle Tumor / Q000175:diagnosis / Q000473:pathology