title: Trajectories of change in adolescent substance use and symptomatology: impact of paternal and maternal substance use disorders.
abstract: The effects of paternal and maternal substance use disorders (SUDs) on trajectories of change in adolescent offspring nicotine, alcohol, and drug use and symptomatology were investigated in a population-based sample of adolescent twins (N = 1,514). Adolescent and parental substance phenotypes were assessed when most adolescents were 11 years old, with 2 assessments of adolescents approximately every 3 years thereafter. Growth curves were fit using hierarchical linear modeling. Results indicated acceleration of substance involvement during adolescence, particularly for boys. Paternal and maternal SUD were each associated with more extreme trajectories. There was evidence for an additive, rather than interactive, combined parental effect. Findings help clarify the impact of paternal and maternal SUD on the development of substance involvement during adolescence.
authors: Department of Psychology, University of Minnesota, Twin Cities Campus, Minneapolis, MN 55455, USA.
authors: Brent
authors: B
authors: Walden
authors: William G
authors: WG
authors: Iacono
authors: Matt
authors: M
authors: McGue
mesh_terms: D000293:Adolescent; D000428:Alcohol Drinking / Q000639:trends*; D000437:Alcoholism; D002648:Child; D016241:Child of Impaired Parents / Q000523:psychology* / Q000706:statistics & numerical data*; D005260:Female; D006801:Humans; D008297:Male; D010290:Parents / Q000523:psychology*; D010641:Phenotype; D019966:Substance-Related Disorders / Q000175:diagnosis / Q000453:epidemiology / Q000523:psychology; D014427:Twins / Q000523:psychology*