Treatment of focal hyperhidrosis.
BACKGROUND
Focal hyperhidrosis is not rare, affecting over 2.5% of the population. This condition is often socially and professionally debilitating, leading to significant quality of life impairment. It most commonly involves the axillae, palms, soles, and face.


OBJECTIVE
To review hyperhidrosis and discuss and compare the treatment options currently available.


CONCLUSIONS
Topical or systemic therapies may be helpful for patients with mild disease. Invasive surgical options, although often effective, are limited by complications. More recently, botulinum toxin injection has proven to be a safe and successful treatment for hyperhidrosis and results in high patient satisfaction. Botulinum toxin A (Botox, Allergan Inc., Irvine, CA) is currently approved in the United States, Canada, the United Kingdom, and many other countries for the treatment of axillary hyperhidrosis and is routinely used off-label for other anatomic sites.
Murray
Christian A
CA
Division of Dermatology, University of Toronto, Women's College Hospital, Toronto, ON, Canada. christian.murray@sw.ca
Cohen
Joel L
JL
Solish
Nowell
N
D001365:Axilla; D019274:Botulinum Toxins, Type A / Q000008:administration & dosage / Q000627:therapeutic use; D018680:Cholinergic Antagonists / Q000627:therapeutic use; D006225:Hand; D006801:Humans; D006945:Hyperhidrosis / Q000175:diagnosis / Q000188:drug therapy / Q000503:physiopathology / Q000628:therapy*; D007271:Injections, Intradermal; D007478:Iontophoresis; D015187:Lipectomy; D009465:Neuromuscular Agents / Q000008:administration & dosage / Q000627:therapeutic use; D013562:Sympathectomy
D018680:Cholinergic Antagonists; D009465:Neuromuscular Agents; D019274:Botulinum Toxins, Type A