Acute lower limb ischemia due to thrombo-embolic arterial occlusions in two previously healthy men with markedly elevated Lp(a).
Lipoprotein (a) (Lp(a)) is a well-documented risk factor for atherosclerotic cardiovascular disease. Its role in acute thrombo-embolic occlusions of peripheral arteries is not known. We describe two cases of multiple, acute, peripheral arterial occlusions in two previously healthy men with markedly elevated Lp(a). Both cases had unsatisfactory results after percutaneous and surgical revascularization procedures. Experience yielded in these two cases suggests that when an unfavorable outcome occurs in a peripheral artery disease patient in the absence of the regular risk factors, Lp(a) should be determined and its role investigated.
Bedarida
Gabriella V
GV
Division of Vascular Medicine, Ludwig-Maximilians University Hospital, Munich, Germany.
Hoffmann
Ulrich
U
Tatò
Federico
F
D015901:Angiography, Digital Subtraction; D001157:Arterial Occlusive Diseases / Q000097:blood / Q000150:complications* / Q000000981:diagnostic imaging; D005263:Femoral Artery; D006801:Humans; D007083:Iliac Artery; D007511:Ischemia / Q000097:blood / Q000209:etiology*; D017270:Lipoprotein(a) / Q000097:blood*; D035002:Lower Extremity / Q000098:blood supply*; D008297:Male; D008875:Middle Aged; D011150:Popliteal Artery; D013923:Thromboembolism / Q000097:blood / Q000150:complications* / Q000000981:diagnostic imaging
D017270:Lipoprotein(a)