A case of Kaposi's sarcoma following treatment of membranoproliferative glomerulonephritis and a review of the literature.
Kaposi's sarcoma (KS) is an unusual tumor principally affecting the skin of the lower extremities. Although the association between KS and renal transplant has been well documented, there are a few KS cases in the literature associated with membranoproliferative glomerulonephritis or other glomerular diseases. This report presents a patient with membranoproliferative glomerulonephritis (MPGN) who developed KS following treatment with long-term medium dose glucocorticoid and short-term additional immunosuppressives. The KS cases associated with glomerulonephritis are also reviewed. KS is a rare complication in glomerular diseases that may (or may not) be related to immunosuppression. Hence, immunosuppression treatment should be carefully planned in glomerulonephritis treatment and avoided if they are not essentially necessary.
Agbaht
Kemal
K
Departmant of Internal Medicine Ankara, Hacettepe University, Hacettepe Medical School, Turkey.
Pepedil
Funda
F
Kirkpantur
Alper
A
Yilmaz
Rahmi
R
Arici
Mustafa
M
Turgan
Cetin
C
D005260:Female; D015432:Glomerulonephritis, Membranoproliferative / Q000150:complications* / Q000188:drug therapy; D005938:Glucocorticoids / Q000008:administration & dosage; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage / Q000009:adverse effects*; D008875:Middle Aged; D011239:Prednisolone / Q000008:administration & dosage; D012514:Sarcoma, Kaposi / Q000209:etiology*; D012878:Skin Neoplasms / Q000209:etiology*
D005938:Glucocorticoids; D007166:Immunosuppressive Agents; D011239:Prednisolone