Reactivity to challenge with carbon dioxide as a prospective predictor of panic attacks.
Fear responding induced by carbon dioxide was prospectively evaluated as a risk factor for the development of anxiety pathology in a nonclinical sample (N=404) followed for 2 years. Baseline response to a CO(2) challenge was a very strong predictor of future panic attacks (though not for panic disorder or other anxiety disorders).
Schmidt
Norman B
NB
Department of Psychology, Florida State University, Tallahassee, FL 32306, United States. schmidt@psy.fsu.edu
Maner
Jon K
JK
Zvolensky
Michael J
MJ
D000280:Administration, Inhalation; D000293:Adolescent; D000328:Adult; D001008:Anxiety Disorders / Q000175:diagnosis / Q000235:genetics / Q000523:psychology; D002245:Carbon Dioxide; D005239:Fear / Q000187:drug effects; D005260:Female; D020022:Genetic Predisposition to Disease / Q000235:genetics; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D010200:Panic / Q000187:drug effects*; D016584:Panic Disorder / Q000175:diagnosis* / Q000235:genetics / Q000523:psychology; D010555:Personality Inventory; D011237:Predictive Value of Tests; D011446:Prospective Studies; D018570:Risk Assessment
D002245:Carbon Dioxide