title: Human papillomavirus subtypes are not uncommon.
abstract: While both variants and types of human papillomavirus (HPV) are common, subtypes (2-10% sequence divergence in the L1 gene) have been considered to be rare. We searched GenBank and in-house databases using a 440 nt L1 fragment and identified 7, 30 and 10 subtypes/putative subtypes in the HPV genera Alpha, Beta and Gamma, respectively. The number of types/putative types in each genus was 54, 58 and 103. Thus, there appears to exist at least 47 different subtypes/putative subtypes of HPV and they seem to be particularly common in the genus Beta-papillomavirus.
authors: Department of Laboratory Medicine, Division of Medical Microbiology, Lund University, University Hospital, Malmö, S-205 02 Malmö, Sweden.
authors: Kristina
authors: K
authors: Hazard
authors: Kristin
authors: K
authors: Andersson
authors: Joakim
authors: J
authors: Dillner
authors: Ola
authors: O
authors: Forslund
mesh_terms: D036022:Capsid Proteins / Q000235:genetics; D019295:Computational Biology; D030541:Databases, Genetic; D005838:Genotype; D006801:Humans; D009856:Oncogene Proteins, Viral / Q000235:genetics; D027383:Papillomaviridae / Q000145:classification* / Q000235:genetics; D030361:Papillomavirus Infections / Q000821:virology*; D017385:Sequence Homology
chemical_list: D036022:Capsid Proteins; C114580:HPV L1 protein, Human papillomavirus; D009856:Oncogene Proteins, Viral