Mechanism-based inactivation of benzoylformate decarboxylase, a thiamin diphosphate-dependent enzyme.
Bera
Asim K
AK
Department of Biological Sciences, Purdue University, West Lafayette, Indiana 47907, USA.
Polovnikova
Lena S
LS
Roestamadji
Juliatek
J
Widlanski
Theodore S
TS
Kenyon
George L
GL
McLeish
Michael J
MJ
Hasson
Miriam S
MS
D001665:Binding Sites / Q000187:drug effects; D002262:Carboxy-Lyases / Q000037:antagonists & inhibitors* / Q000737:chemistry / Q000378:metabolism*; D004789:Enzyme Activation; D004791:Enzyme Inhibitors / Q000737:chemistry* / Q000494:pharmacology*; D008958:Models, Molecular; D015394:Molecular Structure; D016958:Pseudomonas putida / Q000201:enzymology; D013835:Thiamine Pyrophosphate / Q000378:metabolism*
D004791:Enzyme Inhibitors; D002262:Carboxy-Lyases; C019778:benzoylformate decarboxylase; D013835:Thiamine Pyrophosphate