title: Depression and the causal role of specific memory system degenerations: link may be supported by reported therapeutic benefits of Omega 3 fatty acids.
abstract: It is well documented that depressed patients, as a result of their illness, often experience some difficulties with their memory. This hypothesis suggests a vice-versa; that it is a gradual impairment and ultimate failure of specific memory systems that may underpin the onset and continuation of a depressive illness. So particular memory systems of the brain may have a greater role to play in clinical depression and associated anxiety than is generally recognised. A common feature of electroconvulsive therapy (ECT) is that it affects patients' short-term memory adversely. However, in line with the hypothesis, it is suggested that the mechanism of action of successful ECT treatment is that it facilitates the repair and reactivation of particular memory systems. One link that has some bearing on this hypothesis is that of Omega 3 fish oil. It has in some cases been observed to aid recovery of depression and possibly prevent relapse. It has been shown to improve memory.
authors: University of Leeds, 9 Sandhill Oval, Leeds, United Kingdom. afrais@tiscali.co.uk
authors: Anthony T
authors: AT
authors: Frais
mesh_terms: D003863:Depression / Q000150:complications* / Q000628:therapy*; D004565:Electroconvulsive Therapy / Q000379:methods*; D015525:Fatty Acids, Omega-3 / Q000008:administration & dosage*; D006801:Humans; D008568:Memory / Q000187:drug effects*; D008569:Memory Disorders / Q000209:etiology* / Q000517:prevention & control*; D008959:Models, Neurological
chemical_list: D015525:Fatty Acids, Omega-3