Use of intraoperative monitoring of somatosensory evoked potentials to prevent ischaemic stroke after surgical exclusion of middle cerebral artery aneurysms.
OBJECTIVE
The aim of this study was to assess the value of monitoring somatosensory evoked potentials (SEP) in the prevention of ischaemic stroke occurring during surgical exclusion of middle cerebral artery aneurysms.


METHODS
SEP monitoring was performed during the surgical exclusion of 131 aneurysms in 122 patients. All SEP variations over 30% were notified to the surgeon and those over 50% were considered as highly significant. If this happened, and in concert with the conduct of the operation, a return to the basal level was systematically sought.


RESULTS
Post-operative ischemic stroke was observed after 15 (11.4%) operations, leading to a permanent neurological deficit in 12 (9.2%). During nine (6.9%) operations there was a highly significant SEP change that persisted, or was only partially reversed, after corrective procedure. Nine of these patients had a post-operative ischaemic stroke. In 25 (19%), operations there was a highly significant SEP change followed by complete recovery. Of these 25 patients, 2 suffered a post-operative ischemic stroke. Following 49 operations (37.4%) with less significant SEP modifications, 4 patients suffered a post-operative stroke (8%). A stroke did not occur in the 48 (36.6%) operations during which there was not a variation in SEP. The strokes were related to temporary clipping in 9 patients to definitive clipping in 3 to sylvian fissure opening in 1 to brain retraction in and to dissection of the aneurysm in 1 (1 case).


CONCLUSIONS
Changes in the SEP correlated well with the occurrence of post-operative stroke. This early detection of ischemia directs attention to the need for measures such as withdrawal of temporary clipping or identification of another factor (e.g. release of brain retraction or repositioning of an occlusive clip) so that the risk of post-operative is reduced.
Penchet
G
G
Service de Neurochirurgie, Centre Hospitalier Pellegrin, Université Victor Segalen Bordeaux 2, Bordeaux, France. guillaume.penchet@chu-bordeaux.fr
Arné
P
P
Cuny
E
E
Monteil
P
P
Loiseau
H
H
Castel
J-P
JP
D000328:Adult; D000344:Afferent Pathways / Q000503:physiopathology; D000368:Aged; D002545:Brain Ischemia / Q000175:diagnosis* / Q000209:etiology / Q000517:prevention & control; D004558:Electric Stimulation; D004568:Electrodiagnosis / Q000379:methods; D005073:Evoked Potentials, Somatosensory / Q000502:physiology*; D006801:Humans; D002532:Intracranial Aneurysm / Q000601:surgery*; D008875:Middle Aged; D020768:Middle Cerebral Artery / Q000503:physiopathology / Q000601:surgery; D016343:Monitoring, Intraoperative / Q000379:methods*; D009431:Neural Conduction / Q000502:physiology; D019635:Neurosurgical Procedures / Q000009:adverse effects; D011183:Postoperative Complications / Q000175:diagnosis* / Q000209:etiology / Q000517:prevention & control; D012189:Retrospective Studies; D013003:Somatosensory Cortex / Q000503:physiopathology; D020521:Stroke / Q000175:diagnosis* / Q000209:etiology / Q000517:prevention & control; D013525:Surgical Instruments / Q000009:adverse effects