Efficiency of trekrezan in experimental bronchopneumonia in rats.
Trekrezan in a dose of 25 mg/kg normalized the lymphocyte immune status and produced an energy-stabilizing effect, which manifested in decreased levels of lactate, ADP, and AMP and increased content of pyruvate and ATP in blood lymphocytes and lung tissue of rats with experimental acute bronchopneumonia.
Zarubina
I V
IV
Department of Pharmacology, S. M. Kirov Military and Medical Academy, St. Petersburg.
Bolekhan
A V
AV
Shabanov
P D
PD
D000085:Acetates / Q000494:pharmacology / Q000627:therapeutic use*; D000244:Adenosine Diphosphate / Q000378:metabolism; D000249:Adenosine Monophosphate / Q000378:metabolism; D000818:Animals; D001996:Bronchopneumonia / Q000188:drug therapy*; D004338:Drug Combinations; D004734:Energy Metabolism / Q000187:drug effects*; D004983:Ethanolamines / Q000494:pharmacology / Q000627:therapeutic use*; D019344:Lactic Acid / Q000378:metabolism; D008168:Lung / Q000378:metabolism; D008214:Lymphocytes / Q000187:drug effects / Q000276:immunology; D019289:Pyruvic Acid / Q000378:metabolism; D051381:Rats
D000085:Acetates; D004338:Drug Combinations; D004983:Ethanolamines; D019344:Lactic Acid; D000249:Adenosine Monophosphate; C047413:crezacin; D000244:Adenosine Diphosphate; D019289:Pyruvic Acid