title: Parkinson's disease and antidepressant drug treatment: a case-register study.
abstract: We estimated the nationwide prevalence rate of antidepressant drug treatment in Parkinson's disease (PD) patients.
  
  
  BACKGROUND
  Very few studies exist on the frequency of antidepressant drug treatment in patients with PD.
  
  
  METHODS
  Patients with a PD diagnosis at first hospital contact were identified and followed for up to 6 years. The subsequent probability of antidepressant drug treatment was estimated and compared to a control group of patients with osteoarthritis.
  
  
  RESULTS
  The probability of antidepressant drug treatment was 3.98 [95% CI: 3.23-4.91) times higher for PD patients than for controls.
  
  
  CONCLUSIONS
  Patients with PD have higher rates of actual antidepressant drug treatment than a control group with osteoarthritis. Still, however, undertreatment of depressive states may be the case.
authors: Department of Psychiatry, University Hospital of Copenhagen Rigshospitalet, Denmark. mette.brandt@rh.dk
authors: Mette
authors: M
authors: Brandt-Christensen
authors: Ana
authors: A
authors: Garcia Lopez
authors: Flemming
authors: F
authors: Mørkeberg Nilsson
authors: Per
authors: P
authors: Kragh Andersen
authors: Lars
authors: L
authors: Vedel Kessing
mesh_terms: D000368:Aged; D000928:Antidepressive Agents / Q000627:therapeutic use*; D015331:Cohort Studies; D003718:Denmark / Q000453:epidemiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010003:Osteoarthritis / Q000188:drug therapy; D010300:Parkinson Disease / Q000188:drug therapy* / Q000453:epidemiology*; D012042:Registries; D012720:Severity of Illness Index
chemical_list: D000928:Antidepressive Agents