Verbal learning and memory deficits in Mild Cognitive Impairment.
Criteria for amnestic MCI rely on the use of delayed recall tasks to establish the presence of memory impairment. This study applied the California Verbal Learning Test to detail memory performance in MCI patients (n=70), as compared to control subjects (n=92) and AD patients (n=21). Learning across the 5 trials was different among the 3 groups. Learning strategy was also different, the MCI group showing less semantic clustering than the control group. However, both MCI patients and controls could benefit from semantic cueing. This study showed that beyond consolidation deficits, MCI patients have marked difficulties in acquisition and recall strategies.
Ribeiro
F
F
Dementia Clinics, Laboratory of Language, Neurology Department, Institute of Molecular Medicine and Faculty of Medicine of Lisbon, Portugal. piparibeiro@mail.telepac.pt
Guerreiro
M
M
De Mendonça
A
A
D000203:Activities of Daily Living; D000368:Aged; D000369:Aged, 80 and over; D000544:Alzheimer Disease / Q000523:psychology; D003072:Cognition Disorders / Q000150:complications* / Q000523:psychology*; D005260:Female; D006801:Humans; D007859:Learning Disabilities / Q000209:etiology* / Q000523:psychology*; D008297:Male; D008569:Memory Disorders / Q000209:etiology* / Q000523:psychology*; D011939:Mental Recall / Q000502:physiology; D008875:Middle Aged; D009483:Neuropsychological Tests; D011569:Psychiatric Status Rating Scales; D011597:Psychomotor Performance / Q000502:physiology; D021641:Recognition, Psychology / Q000502:physiology; D012660:Semantics; D014706:Verbal Learning / Q000502:physiology*