title: [A case of Edwards' syndrome in pregnancy complicated by serologic incompatibility and preeclampsia].
abstract: A case of Edwards' syndrome (trisomy 18) diagnosed in the third pregnancy trimester is described. The diagnosis was based on sonographic examination and cytogenetic amniocentesis. Lethal genetic fetal malformation determined the medical indication to preterm delivery. Additionally, serologic incompatibility during pregnancy was observed, as well as pregnancy induced hypertension turning into preeclampsia after the labour action was evoked. A caesarean section due to obstetric indications was done. Phenotype and lethal congenital malformations in the newborn have confirmed of the chromosome aberration prenatally diagnosed.
authors: I Katedra i Klinika Ginekologii i Połoznictwa Akademii Medycznej we Wrocławiu. marmurawski@yahoo.co.uk
authors: Marek
authors: M
authors: Murawski
authors: Marian
authors: M
authors: Gryboś
authors: Dominika
authors: D
authors: Zalewska
authors: Krzysztof
authors: K
authors: Symonowicz
mesh_terms: D000015:Abnormalities, Multiple / Q000175:diagnosis*; D000328:Adult; D001787:Blood Group Incompatibility / Q000175:diagnosis*; D002887:Chromosomes, Human, Pair 18; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D011225:Pre-Eclampsia / Q000175:diagnosis*; D011247:Pregnancy; D011263:Pregnancy Trimester, Third; D011296:Prenatal Diagnosis; D013577:Syndrome; D014314:Trisomy / Q000175:diagnosis*