Tigliane diterpenoids from the stem bark of Neoboutonia macrocalyx.
Neoboutonia macrocalyx is a plant used by traditional healers among the Meru community in Kenya. Chromatographic fractionation of the petroleum ether and dichloromethane extracts of this plant yielded one known (1) and three new tigliane-type diterpenoids (2-4). The chemical structures of the isolated compounds were established through spectroscopic data interpretation.
Kirira
Peter G
PG
Department of Chemistry, School of Pure and Applied Sciences, Kenyatta University, P.O. Box 43844, Nairobi 00100, Kenya.
Rukunga
Geoffrey M
GM
Wanyonyi
Alphonse W
AW
Muthaura
Charles N
CN
Mungai
Geoffrey M
GM
Machocho
Alex K
AK
Ndiege
Isaiah O
IO
D000818:Animals; D004224:Diterpenes / Q000737:chemistry* / Q000302:isolation & purification* / Q000494:pharmacology; D019665:Euphorbiaceae / Q000737:chemistry*; D007630:Kenya; D016488:Medicine, African Traditional; D015394:Molecular Structure; D024301:Plant Bark / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D010963:Plasmodium falciparum / Q000187:drug effects
D004224:Diterpenes