Comparison of Ligasure, SurgRx, and suture techniques in intra-abdominal adhesions that occur after liver resection in rats: an experimental study.
Mechanical trauma, thermal injury, tissue ischemia during the operation, postoperative infections, and foreign body reactions are important factors for adhesion formation. Bleeding and bile leakage after liver resections can also cause intra-abdominal adhesions. We aimed to evaluate the intra-abdominal adhesions after liver resection in rats using Ligasure and SurgRx. Twenty-seven Sprague-Dawley rats were used in the study. Three random groups were formed. Two liver lobes were resected from the middle using sutures in group A, Ligasure in group B, and SurgRx in group C. Relaparotomy was performed at postoperative day 7 to evaluate intra-abdominal adhesion formation. Adhesion formation was significantly lower in the SurgRx group compared with the suture and Ligasure groups. SurgRx and Ligasure provide effective hemostasis in liver resection without leaving foreign bodies such as clips and knots behind. SurgRx was superior to suture and Ligasure techniques in terms of adhesion formation in our model.
Sahin
Dursun Ali
DA
Department of General Surgery, Afyon Kocatepe University, School of Medicine, Afyonkarahisar, Turkey. dursunalisahin@yahoo.com
Kusaslan
Ramazan
R
Sahin
Onder
O
Akbulut
Gokhan
G
Ozen
Oguz Aslan
OA
Dilek
Osman Nuri
ON
D000005:Abdomen; D000818:Animals; D006498:Hepatectomy; D008297:Male; D051381:Rats; D017207:Rats, Sprague-Dawley; D013536:Suture Techniques / Q000009:adverse effects; D000267:Tissue Adhesions / Q000209:etiology / Q000503:physiopathology