Large primary meningeal melanoma in an adult patient with neurocutaneous melanosis.
Neurocutaneous melanosis is often associated with melanoma of the central nervous system. Due to the inconspicuously looking cutaneous melanosis additional examinations are often not performed. We describe a patient with cutaneous melanosis who presented with neurological symptoms due to a large primary meningeal melanoma. The diagnosis of neurocutaneous melanosis was made. This case is an illustration of melanoma development in the central nervous system in a patient with cutaneous melanosis. This phenomenon should be kept in mind when observing patients with such skin lesions, even if they are of minor extent.
Kiecker
Felix
F
Department of Dermatology and Allergy, Skin Cancer Center, Charité-Universitätsmedizin Berlin, Charitéplatz 1, 10117 Berlin, Germany.
Hofmann
Maja A
MA
Audring
Heike
H
Brenner
Aeilke
A
Labitzke
Christine
C
Sterry
Wolfram
W
Trefzer
Uwe
U
D000328:Adult; D001929:Brain Edema / Q000175:diagnosis; D003713:Dendritic Cells / Q000473:pathology; D020405:Dermis / Q000473:pathology; D004388:Dura Mater / Q000473:pathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008545:Melanoma / Q000175:diagnosis* / Q000473:pathology; D008548:Melanosis / Q000175:diagnosis* / Q000473:pathology; D008577:Meningeal Neoplasms / Q000175:diagnosis* / Q000473:pathology; D020752:Neurocutaneous Syndromes / Q000175:diagnosis* / Q000473:pathology; D009460:Neurologic Examination; D014057:Tomography, X-Ray Computed