title: Sub-optimal function of the auditory brainstem in term infants with transient low Apgar scores.
abstract: OBJECTIVE
  To assess functional integrity of the auditory brainstem in neonates with transient low Apgar scores.
  
  
  METHODS
  Forty-two term infants were studied with brainstem auditory evoked response (BAER) using the maximum length sequence during the first month of life. All had transient low Apgar scores but no clinical signs of hypoxic-ischaemic encephalopathy (HIE).
  
  
  RESULTS
  The latencies of BAER waves I and III in these infants were similar to those of age-matched normal controls at all click rates (91/s, 227/s, 455/s and 910/s) during the period studied. Wave V latency was increased at 910/s on day 1 (P<0.01), but did not differ from that in the controls on any other days. I-V interval was increased significantly at 455/s and 910/s on day 1 (P<0.01 and 0.001) and day 3 (P<0.05 and 0.01). On days 5 and 7, BAER wave latencies and intervals were similar to those in the controls. On day 30, all latencies and intervals reached the values in the controls. No abnormalities were seen in BAER wave amplitude variables on any days.
  
  
  CONCLUSIONS
  Neonates with transient low Apgar scores but without HIE had a significant increase in I-V interval at very high click rates on the first three days of life.
  
  
  CONCLUSIONS
  Brainstem auditory function is sub-optimal during the first few days in neonates with transient low Apgar scores.
authors: Children's Hospital, Fudan University, Shanghai, China. zedong.jiang@paediatrics.ox.ac.uk
authors: Ze D
authors: ZD
authors: Jiang
authors: Xu
authors: X
authors: Xiu
authors: Dorothea M
authors: DM
authors: Brosi
authors: Xiao M
authors: XM
authors: Shao
authors: Andrew R
authors: AR
authors: Wilkinson
mesh_terms: D000161:Acoustic Stimulation; D000375:Aging / Q000502:physiology; D001034:Apgar Score; D003627:Data Interpretation, Statistical; D004569:Electroencephalography; D016057:Evoked Potentials, Auditory, Brain Stem / Q000502:physiology*; D005260:Female; D006801:Humans; D002534:Hypoxia, Brain / Q000503:physiopathology; D007231:Infant, Newborn; D008297:Male; D011247:Pregnancy; D011256:Pregnancy Outcome