title: Impact of preload alterations by haemodialysis on the Tei index: comparison between pulsed flow and tissue Doppler analyses.
abstract: OBJECTIVE
  The aim of this study is to evaluate and compare the impact of preload alterations by haemodialysis (HD) on the Tei index obtained by pulsed Doppler echocardiography (PDE-Tei index) and tissue Doppler echocardiography (TDE-Tei index).
  
  
  RESULTS
  Thirty-eight uraemic patients underwent echocardiography 1 hour before and 1 hour after HD was studied. Before HD, PDE- and TDE-Tei indices had a weak correlation (r = 0.439, P = 0.006). After HD, the correlation became stronger (r = 0.794, P < 0.001). After HD, body weight (P < 0.001), early transmitral filling wave peak velocity (E) (P < 0.00 1), early diastolic mitral annular velocity (Em) (P < 0.00 1), and E/Em (P = 0.00 1) decreased and PDE- (P < 0.00 1) and TDE-Tei indices (P = 0.022) increased significantly. In addition, after HD, body weight reduction had a significant correlation with E decrease and PDE- and TDE-Tei index increase (P < 0.00 1, P = 0.005, and P = 0.016, respectively). A subgroup comparison showed that in patients with body weight reduction < 3 kg, the PDE-Tei index (P = 0.003) increased significantly but TDE-Tei index (P = 0.209) did not change after HD. In patients with body weight reduction > or = 3 kg, both the PDE- and TDE-Tei indices (P = 0.003 and 0.042, respectively) increased significantly after HD.
  
  
  CONCLUSIONS
  Both the PDE- and TDE-Tei indices are preload-dependent indicators. However, TDE-Tei index is less preload-dependent and is more accurate in assessing global left ventricular function in patients with body weight reduction < 3 kg after HD.
authors: Division of Cardiology, Department of Internal Medicine, Kaohsiung Medical University Chung-Ho Memorial Hospital Kaohsiung, Taiwan.
authors: Ho-Ming
authors: HM
authors: Su
authors: Tsung-Hsien
authors: TH
authors: Lin
authors: Wen-Chol
authors: WC
authors: Voon
authors: Hung-Chun
authors: HC
authors: Chen
authors: Feng-Hsien
authors: FH
authors: Lin
authors: Mei-Chuan
authors: MC
authors: Kuo
authors: Kun-Tai
authors: KT
authors: Lee
authors: Chih-Sheng
authors: CS
authors: Chu
authors: Wen-Ter
authors: WT
authors: Lai
authors: Sheng-Hsiung
authors: SH
authors: Sheu
mesh_terms: D003935:Diagnostic Techniques, Cardiovascular; D003971:Diastole; D006339:Heart Rate; D006352:Heart Ventricles / Q000000981:diagnostic imaging*; D006801:Humans; D008875:Middle Aged; D008943:Mitral Valve; D011379:Prognosis; D011674:Pulse; D006435:Renal Dialysis; D013318:Stroke Volume; D013997:Time Factors; D018608:Ultrasonography, Doppler; D014511:Uremia / Q000000981:diagnostic imaging; D018487:Ventricular Dysfunction, Left / Q000000981:diagnostic imaging*