A child with 18p- syndrome: a case report.
18p- syndrome is caused by the deletion of all or a portion of genetic material on the short (p) arm of chromosome 18. It was first described in 1963 and since then there have been a variety of clinical characteristics associated with this syndrome. The patient described presented with learning difficulties, epilepsy, a characteristic round face and anti-mongoloid slant to the eyes. Orally he had a single maxillary central incisor and a high caries rate which necessitated comprehensive dental treatment under general anesthesia.
Naudi
Antoniella Busuttil
AB
Department of Paediatric Dentistry, Royal Hospital for Sick Children, Glasgow, Scotland.
Fung
Diane E
DE
D002648:Child; D002872:Chromosome Deletion; D025063:Chromosome Disorders / Q000473:pathology*; D002887:Chromosomes, Human, Pair 18 / Q000235:genetics*; D019465:Craniofacial Abnormalities / Q000473:pathology*; D003730:Dental Care for Persons with Disabilities; D004827:Epilepsy; D019066:Facies; D006801:Humans; D007180:Incisor / Q000002:abnormalities*; D008607:Intellectual Disability; D008297:Male; D013577:Syndrome; D014071:Tooth Abnormalities / Q000473:pathology