title: Factors associated with one step surgery in case of non-palpable breast cancer.
abstract: OBJECTIVE
  To examine factors associated with one step surgery in case of non-palpable breast cancer.
  
  
  METHODS
  Clinical data of 152 consecutively diagnosed patients with breast cancer were analyzed retrospectively. Preoperative diagnostic findings were divided in subgroups: mammographically visible mass/microcalcifications/sonographically visible mass/sonographically visible architectural distortion. Correlation between tumor-size, radiologic tumor morphology, quality of localization and number of operation was evulated. For localization exact wire position was defined less than 3mm apart from the lesion.
  
  
  RESULTS
  One hundred and thirty-six patients attempted breast conservation and underwent preoperative tumor localization. Fourteen of 16 patients had mastectomy without preoperative localization. Average tumor size was 12mm for one-operation, and 17mm for re-operation. Significant correlation (p<0.001) was found between one operation and masses visible in mammograms (55/62 (89%) patients) or sonography (53/64 (83%) patients). Significant correlation was found (p<0.001) between more re-operation and microcalcifications in mammograms (33/89 (37% patients). In 123/138 (89%) cases wire position was central, in 15/138 (11%) cases distance was maximally 10mm. No significant correlation was found between number of operation and wire position. Re-operation was required in 38 cases.
  
  
  CONCLUSIONS
  Mammographically or sonographically visible mass, small size of tumors, preoperative percutaneous biopsy and exact preoperative localization are important for a single step procedure for definite surgical treatment, that we found in 74% of the patients.
authors: Breast Care Center, University Hospital Schleswig-Holstein Campus Kiel, Michaelisstr. 16, 24105 Kiel, Germany. fschaefer@email.uni-kiel.de
authors: Fritz K
authors: FK
authors: Schaefer
authors: I
authors: I
authors: Eden
authors: P J
authors: PJ
authors: Schaefer
authors: D
authors: D
authors: Peter
authors: W
authors: W
authors: Jonat
authors: M
authors: M
authors: Heller
authors: I
authors: I
authors: Schreer
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001706:Biopsy / Q000379:methods; D001943:Breast Neoplasms / Q000000981:diagnostic imaging / Q000601:surgery*; D002114:Calcinosis / Q000000981:diagnostic imaging; D002278:Carcinoma in Situ / Q000000981:diagnostic imaging / Q000601:surgery; D018270:Carcinoma, Ductal, Breast / Q000000981:diagnostic imaging / Q000601:surgery; D005260:Female; D006801:Humans; D008197:Lymph Node Excision; D008327:Mammography / Q000379:methods; D008408:Mastectomy; D015412:Mastectomy, Segmental; D008875:Middle Aged; D010173:Palpation; D015641:Radiography, Interventional; D012086:Reoperation; D012189:Retrospective Studies; D021701:Sentinel Lymph Node Biopsy; D013238:Stereotaxic Techniques; D018084:Ultrasonography, Interventional; D016217:Ultrasonography, Mammary / Q000379:methods