Neoplasms of the fallopian tube and broad ligament: a selective survey including historical perspective and emphasising recent developments.
Recent contributions on selected aspects of the pathology of tubal and paratubal neoplasms are reviewed after a brief historical perspective. The most important, considering both frequency and clinical importance, are those pertaining to tubal carcinoma. These can be grouped as follows: (1) recognition that endometrioid carcinoma is the second most common carcinoma of the tube, after serous, and other variants of müllerian carcinoma are rare; (2) expansion of knowledge about the morphological spectrum of tubal endometrioid carcinoma; (3) modifications of the FIGO staging system; (4) heightened appreciation of the occasional origin of tubal carcinomas from the tubal fimbriae; (5) increased awareness of early carcinoma arising in patients with the BRCA mutation; (6) greater recognition of the propensity for non-tuberculous salpingitis with reactive atypia to mimic carcinoma. Brief consideration then follows of certain other tubal and paratubal neoplasms including those of the broad ligament, emphasising issues in differential diagnosis.
Young
Robert H
RH
James Homer Wright Pathology Laboratories, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA. rhyoung@partners.org
D001956:Broad Ligament / Q000473:pathology*; D005185:Fallopian Tube Neoplasms / Q000266:history* / Q000473:pathology*; D005260:Female; D049669:History, 16th Century; D049672:History, 19th Century; D049673:History, 20th Century; D049674:History, 21st Century; D006801:Humans