title: A 3D trajectory for undersampling k-space in MRSI applications.
abstract: Magnetic resonance spectroscopic imaging (MRSI) is a noninvasive technique for producing spatially localized spectra. MRSI presents the important challenge of reducing the scan time while maintaining the spatial resolution. The preferred approach for this is to use time-varying readout gradients to collect the spatial and chemical-shift information. Fast, three-dimensional (3D) spatial encoded methods also reduce the scan time. Despite the existence of several new and faster 3D encoded methods, or k-space trajectories, for magnetic resonance imaging (MRI), only stack of spirals and echo planar have been studied in 3D MRSI. A novel formulation for designing fast, 3D k-space trajectory applicable to 3D MRSI is presented. This approach is simple and consists of rays expanding from the origin of k-space into a revolving sphere, collecting spectral data of all 3D spatial k-space at different times in the same scan. This article describes this new method and presents some results of its application to 3D MRSI. This technique allows some degree of undersampling; hence, it is possible to reconstruct high-quality undersampled spectroscopic imaging in order to recognize different compounds in short scan times. Additionally, the method is tested in regular 3D MRI. This proposed method can also be used for dynamic undersampled imaging.
authors: Department of Electrical Engineering, Pontificia Universidad Católica de Chile, Casilla 306-22, Santiago, Chile.
authors: Sergio
authors: S
authors: Uribe
authors: Andrés
authors: A
authors: Guesalaga
authors: Roberto
authors: R
authors: Mir
authors: Marcelo
authors: M
authors: Guarini
authors: Pablo
authors: P
authors: Irarrázaval
mesh_terms: D000465:Algorithms; D003198:Computer Simulation; D007089:Image Enhancement / Q000379:methods*; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D021621:Imaging, Three-Dimensional / Q000379:methods*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D008954:Models, Biological; D009716:Numerical Analysis, Computer-Assisted; D015203:Reproducibility of Results; D018401:Sample Size; D012680:Sensitivity and Specificity; D012815:Signal Processing, Computer-Assisted