title: Evaluation of bilayer disks as plant cell membrane models in partition studies.
abstract: We have studied the partitioning of a set of phenolic compounds used as lignin precursor models into lipid bilayer disks and liposomes. The bilayer disks are open bilayer structures stabilized by polyethylene glycol-conjugated lipids. Our results indicate that disks generate more accurate partition data than do liposomes. Furthermore, we show that the partitioning into the membrane phase is reduced slightly if disks composed of 1,2-distearoyl-sn-glycero-3-phosphocholine and cholesterol are exchanged for disks with a lipid composition mimicking that of the root tissue of Zea mays L.
authors: Department of Biochemistry and Organic Chemistry, Biomedical Center, Uppsala University, SE-751 23 Uppsala, Sweden.
authors: Elisabet
authors: E
authors: Boija
authors: Anna
authors: A
authors: Lundquist
authors: Katarina
authors: K
authors: Edwards
authors: Gunnar
authors: G
authors: Johansson
mesh_terms: D002462:Cell Membrane / Q000737:chemistry*; D002474:Cell-Free System / Q000737:chemistry; D002627:Chemistry, Physical / Q000379:methods; D002784:Cholesterol / Q000737:chemistry; D008051:Lipid Bilayers / Q000737:chemistry*; D008081:Liposomes / Q000737:chemistry*; D008567:Membranes, Artificial; D008954:Models, Biological; D008956:Models, Chemical; D015394:Molecular Structure; D059828:Plant Cells; D011092:Polyethylene Glycols / Q000737:chemistry; D013499:Surface Properties / Q000187:drug effects; D013816:Thermodynamics
chemical_list: D008051:Lipid Bilayers; D008081:Liposomes; D008567:Membranes, Artificial; D011092:Polyethylene Glycols; D002784:Cholesterol