Nonequilibrium hollow-fiber liquid-phase microextraction with in situ derivatization for the measurement of triclosan in aqueous samples by gas chromatography-mass spectrometry.
Hollow-fiber liquid-phase microextraction (HF-LPME), a relatively new sample preparation technique, has attracted much interest in the field of environmental analysis. In the current study, a novel method based on hollow-fiber liquid-phase microextraction with in situ derivatization and gas chromatography-mass spectrometry for the measurement of triclosan in aqueous samples is described. Hollow-fiber liquid-phase microextraction conditions such as the type of extraction solvent, the stirring rate, the volume of derivatizing reagent, and the extraction time were investigated. When the conditions had been optimized, the linear range was found to be 0.05-100 microg l(-1) for triclosan, and the limit of detection to be 0.02 microg l(-1). Tap water and surface water samples collected from our laboratory and Wohushan reservoir, respectively, were successfully analyzed using the proposed method. The recoveries from the spiked water samples were 83.6 and 114.1%, respectively; and the relative standard deviation (RSD) at the 1.0 microg l(-1) level was 6.9%.
Zhao
Ru-Song
RS
Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology, Ministry of Education, Department of Chemistry, Tsinghua University, Beijing 100084, China. zrswangx@yahoo.com.cn
Yuan
Jin-Peng
JP
Li
Hai-Fang
HF
Wang
Xu
X
Jiang
Ting
T
Lin
Jin-Ming
JM
D000891:Anti-Infective Agents, Local / Q000032:analysis*; D008401:Gas Chromatography-Mass Spectrometry / Q000379:methods*; D012680:Sensitivity and Specificity; D014260:Triclosan / Q000032:analysis*; D014874:Water Pollutants, Chemical / Q000032:analysis*
D000891:Anti-Infective Agents, Local; D014874:Water Pollutants, Chemical; D014260:Triclosan