title: Studies of interactions between platinum(II) complexes and some biologically relevant molecules.
abstract: The reactions of Pt(II) complexes, cis-[Pt(NH3)2Cl2], [Pt(terpy)Cl]+, [Pt(terpy)(S-cys)]2+, and [Pt(terpy)(N7-guo)]2+, where terpy=2,2':6',2''-terpyridine, S-cys=L-cysteine, and N7-guo=guanosine, with some biologically relevant ligands such as guanosine-5'-monophosphate (5'-GMP), L-cysteine, glutathione (GSH) and some strong sulfur-containing nucleophiles such as diethyldithiocarbamate (dedtc), thiosulfate (sts), and thiourea (tu), were studied in aqueous 0.1 M Hepes at pH of 7.4 using UV-vis, stopped-flow spectrophotometry, and 1H NMR spectroscopy.
authors.affiliation: University of Kragujevac, Faculty of Medicine, S. Markovića 69, 34000 Kragujevac, Serbia.
authors.forename: Dejan
authors.initials: D
authors.lastname: Petrović
authors.forename: Biljana
authors.initials: B
authors.lastname: Stojimirović
authors.forename: Biljana
authors.initials: B
authors.lastname: Petrović
authors.forename: Zorica M
authors.initials: ZM
authors.lastname: Bugarcić
authors.forename: Zivadin D
authors.initials: ZD
authors.lastname: Bugarcić
mesh_terms: D007700:Kinetics; D009682:Magnetic Resonance Spectroscopy; D017671:Platinum Compounds / Q000737:chemistry*; D013056:Spectrophotometry, Ultraviolet
chemical_list: D017671:Platinum Compounds