Six-minute walk test in Chagas cardiomyopathy.
We studied systematically, for the first time, the utility of the six-minute walk test (6MWT) in Chagas disease. The walked distance at 6MWT correlated negatively with the increased circulating levels of monocyte chemoattractant protein (MCP-1, r=-0.358, p=0.04) and natriuretic peptide type B (BNP, r=-0.349, p=0.04), as well as positively with ejection fraction deterioration (r=0.451, p=0.004), indicating that submaximal functional capacity of chagasic patients is related to the severity of the cardiopathy. 6MWT may constitute an auxiliary tool in the evaluation of the clinical status of Chagas disease patients.
Sousa
Lidiane
L
Botoni
Fernando Antônio
FA
Britto
Raquel R
RR
Rocha
Manoel Otávio da Costa
MO
Teixeira
Antonio Lúcio
AL
Teixeira
Mauro Martins
MM
Reis
Adelina M
AM
Oliveira
Bráulio Muzzi R
BM
Ribeiro
Antonio L
AL
D002598:Chagas Cardiomyopathy / Q000097:blood* / Q000503:physiopathology*; D018932:Chemokine CCL2 / Q000097:blood*; D005080:Exercise Test; D017079:Exercise Tolerance; D005260:Female; D006801:Humans; D007249:Inflammation; D008297:Male; D008875:Middle Aged; D020097:Natriuretic Peptide, Brain / Q000097:blood*; D010865:Pilot Projects; D013318:Stroke Volume; D013997:Time Factors
D018932:Chemokine CCL2; D020097:Natriuretic Peptide, Brain