Combining immune cell and viral therapy for the treatment of cancer.
A variety of viral-based and immune cell therapies have been proposed for use in the treatment of cancer. One possible approach to improve the effectiveness of these biological agents may be to combine them such that we can take advantage of natural immune cell-pathogen relationships. Here we discuss these potential approaches with particular emphasis on the use of immune cells as carrier vehicles to deliver viral therapies to the tumor.
Thorne
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Bio-X program, Molecular Imaging Program at Stanford (MIPS) and Department of Pediatrics, Stanford University, Stanford, CA, USA. sthorne@stanford.edu
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D000818:Animals; D003131:Combined Modality Therapy; D016219:Immunotherapy, Adoptive; D009369:Neoplasms / Q000628:therapy*; D050130:Oncolytic Virotherapy