Temporal dynamics of visuo-tactile extinction within and between hemispaces.
The ability to detect left-sided stimuli (visual or tactile) was studied in visual and tactile extinction (RBD) patients and in healthy (C) subjects. Stimuli were single or double; double stimuli were always cross-modal and could be released across the 2 hemispaces or within the same hemispace. Moreover, the stimuli could be either simultaneous or separated by 1 of 3 different asynchronies (105, 505, 905 ms). C subjects were perfect in all conditions. RBD patients omitted the contralesional tactile stimulus in bilateral trials (across space, classical extinction). They also omitted the tactile stimulus in unilateral left trials (within hemispace). Both effects showed the same temporal modulation with lower extinction rates at longer stimulus onset asynchronies. Results suggest that attentional processing of a visual stimulus inhibits processing of a tactile one, even if both are delivered in the same contralesional hemispace.
Costantini
Marcello
M
Dipartimento di Scienze Cliniche e Bioimmagini, Universita G. D'Annunzio, Chieti, Italy. marcello.costantini@unich.it
Bueti
Domenica
D
Pazzaglia
Mariella
M
Aglioti
Salvatore M
SM
D000368:Aged; D000704:Analysis of Variance; D001931:Brain Mapping; D005108:Extinction, Psychological; D005260:Female; D007839:Functional Laterality; D006801:Humans; D007600:Judgment / Q000502:physiology; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D010468:Perceptual Disorders / Q000473:pathology / Q000503:physiopathology*; D010812:Physical Stimulation / Q000379:methods; D011930:Reaction Time / Q000502:physiology; D013028:Space Perception / Q000502:physiology*; D014110:Touch / Q000502:physiology*