Selective anterograde amnesia with thalamus and hippocampal lesions in neuro-Behcet's disease.
Anterograde amnesia and minimal retrograde amnesia with thalamic and hippocampal lesions in neuro-Behcet's disease is rare. A 50-year-old man presented with forgetfulness and severe memory disturbance after suffering multiple oral and genital aphthous ulcers with erythema nodosum. A neurological examination and a neuropsychological assessment revealed prominent anterograde memory impairment without focal neurological deficits. On brain MRI there were high signal intensity lesions involving right anterior thalamus, left posterior basal ganglia, and left hippocampus. This is a quite selective anterogrde memory deficit in a case of neuro-Behcet's disease caused by parenchymal lesions in the thalamus and hippocampus.
Park
Kyung Won
KW
Department of Neurology, Dong-A University College of Medicine, Seo-gu, Busan 602-715, Republic of Korea. neuropark@dau.ac.kr
Seo
Jung Hwa
JH
Yoon
Go-Un
GU
D020324:Amnesia, Anterograde / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D001479:Basal Ganglia / Q000473:pathology; D001528:Behcet Syndrome / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D001706:Biopsy; D001927:Brain Diseases / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D004292:Dominance, Cerebral / Q000502:physiology; D005500:Follow-Up Studies; D006624:Hippocampus / Q000473:pathology; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D011239:Prednisolone / Q000008:administration & dosage; D012867:Skin / Q000473:pathology; D013786:Thalamic Diseases / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D013788:Thalamus / Q000473:pathology
D007166:Immunosuppressive Agents; D011239:Prednisolone