title: Diastereomeric recognition of chiral foldamer receptors for chiral glucoses.
abstract: [reaction: see text] Three chiral aromatic hydrazide foldamers have been designed and synthesized, in which two R- or S-proline units were incorporated at the terminals of their backbones. The 1H NMR, circular dichroism (CD), and fluorescent experiments and molecular dynamics simulations revealed that the foldamers adopted a chiral helical conformation and complexed alkylated glucoses in chloroform with a good diastereomeric selectivity.
authors.affiliation: State Key Laboratory of Bio-Organic and Natural Products Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 354 Fenglin Lu, Shanghai 200032, China.
authors.forename: Chuang
authors.initials: C
authors.lastname: Li
authors.forename: Gui-Tao
authors.initials: GT
authors.lastname: Wang
authors.forename: Hui-Ping
authors.initials: HP
authors.lastname: Yi
authors.forename: Xi-Kui
authors.initials: XK
authors.lastname: Jiang
authors.forename: Zhan-Ting
authors.initials: ZT
authors.lastname: Li
authors.forename: Ren-Xiao
authors.initials: RX
authors.lastname: Wang
mesh_terms: D002942:Circular Dichroism; D005947:Glucose / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D012996:Solutions; D013237:Stereoisomerism
chemical_list: D012996:Solutions; D005947:Glucose