title: A case of inherited erythromelalgia.
abstract: BACKGROUND
  A 15-year-old boy presented with recurrent episodes of erythema and burning pain in the distal extremities, which he had experienced since early childhood. The episodes were triggered by heat or exertion. His medical history revealed an extensive six-generation family history of similar symptoms.
  
  
  METHODS
  Neurological examination, MRI brain scan, electromyography, skin biopsy, laboratory blood testing, and DNA analysis.
  
  
  METHODS
  Juvenile onset primary erythromelalgia.
  
  
  RESULTS
  Genetic counseling, and symptomatic management of neuropathic pain.
authors.affiliation: Department of Neurology, Yale University School of Medicine, New Haven, CT 06520-8018, USA.
authors.forename: Steven P
authors.initials: SP
authors.lastname: Novella
authors.forename: Fuki M
authors.initials: FM
authors.lastname: Hisama
authors.forename: Sulayman D
authors.initials: SD
authors.lastname: Dib-Hajj
authors.forename: Stephen G
authors.initials: SG
authors.lastname: Waxman
mesh_terms: D000200:Action Potentials / Q000235:genetics; D000293:Adolescent; D004576:Electromyography / Q000379:methods; D004916:Erythromelalgia / Q000150:complications / Q000235:genetics* / Q000473:pathology; D005192:Family Health; D005727:Ganglia, Spinal / Q000473:pathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009154:Mutation; D062556:NAV1.7 Voltage-Gated Sodium Channel; D009437:Neuralgia / Q000209:etiology / Q000235:genetics*; D009474:Neurons / Q000502:physiology; D010649:Phenylalanine / Q000235:genetics; D015222:Sodium Channels / Q000235:genetics*; D014633:Valine / Q000235:genetics
chemical_list: D062556:NAV1.7 Voltage-Gated Sodium Channel; C486866:SCN9A protein, human; D015222:Sodium Channels; D010649:Phenylalanine; D014633:Valine