Solid organ transplantation at the National Institutes of Health: development of a research-based transplantation practice.
The National Institutes of Health has established a clinical transplant research program focusing on translational research in kidney transplantation. The program has been developed with a multidisciplinary approach under a common administrative structure that integrates transplant physicians and surgeons with clinical laboratory and data analysis support personnel. The program has achieved excellent clinical outcomes despite focusing exclusively on investigational methods and serving a diverse and medically complex patient population. Novel approaches toward consenting, computer integration, and tissue acquisition have been layered over interventional and observational studies to serve the scientific mission while delivering quality transplant care.
Kirk
Allan D
AD
The Transplantation Branch, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) and The Laboratory of Pathology, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
Hale
Douglas A
DA
Ford
Elizabeth
E
Kleiner
David E
DE
Kampen
Robert L
RL
Elster
Eric A
EA
Swanson
S John
SJ
Cendales
Linda C
LC
Cropper
Tracy
T
Hale
Liz
L
Jordan
Susan
S
Koussis
Trish
T
Peretti
Julie
J
Sloane
Anne
A
Salaita
Christine
C
Ring
Michael
M
Chamberlain
Christine
C
Mannon
Roslyn B
RB
D005260:Female; D006801:Humans; D007165:Immunosuppression Therapy; D016030:Kidney Transplantation / Q000276:immunology / Q000706:statistics & numerical data; D008297:Male; D008991:Monitoring, Physiologic; D009316:National Institutes of Health (U.S.); D016377:Organ Transplantation / Q000523:psychology / Q000706:statistics & numerical data*; D018579:Patient Selection; D011184:Postoperative Period; D044469:Racial Groups; D012984:Software; D009927:Tissue and Organ Procurement / Q000458:organization & administration; D014481:United States