title: [Acute myocardial infarction associated to the Sildenafil consumption. A case report and review of the literature].
abstract: Erectile dysfunction affects more than 30 million men in The United States. Since the FDA approved the use of Sildenafil, prescription of this medication has been raising. Adverse events of Sildenafil includes: fatigue, dyspnea, and hypotension. Reported adverse cardiac events associated with the medication use include myocardial infarction, ventricular tachycardia, angina and death, raising concerns about the safety of this agent in patients with coronary artery disease. Published guidelines regarding the management of cardiac patients with erectile dysfunction suggest that Sildenafil may be hazardous in patients with ischemic heart disease. In patients using Sildenafil, myocardial infarctions have been reported to the Food and Drug Administration. Now, we report a patient with myocardial infarction after taking 100 mg of Sildenafil without sexual activity.
authors.affiliation: Servicio de Urologia Hospital Pablo Tobón Uribe y Universidad CES. juangvl@gmail.com
authors.forename: J G
authors.initials: JG
authors.lastname: Velásquez López
authors.forename: C A
authors.initials: CA
authors.lastname: Agudelo Restrepo
authors.forename: D
authors.initials: D
authors.lastname: Yepes Gómez
authors.forename: C A
authors.initials: CA
authors.lastname: Uribe Trujillo
mesh_terms: D000368:Aged; D007172:Erectile Dysfunction / Q000188:drug therapy; D006801:Humans; D008297:Male; D009203:Myocardial Infarction / Q000139:chemically induced*; D010726:Phosphodiesterase Inhibitors / Q000009:adverse effects*; D010879:Piperazines / Q000009:adverse effects*; D011687:Purines / Q000009:adverse effects; D000068677:Sildenafil Citrate; D013450:Sulfones / Q000009:adverse effects*
chemical_list: D010726:Phosphodiesterase Inhibitors; D010879:Piperazines; D011687:Purines; D013450:Sulfones; D000068677:Sildenafil Citrate