title: Mass spectrometry-based strategies for characterization of histones and their post-translational modifications.
abstract: Due to the intimate interactions between histones and DNA, the characterization of histones has become the focus of great attention. A series of mass spectrometry-based technologies have been dedicated to the characterization and quantitation of different histone forms. This review focuses on the discussion of mass spectrometry-based strategies used for the characterization of histones and their post-translational modifications.
authors.affiliation: The Ohio State Unviersity, Department of Molecular Virology Immunology & Medical Genetics, Human Cancer Genetics, Columbus, OH, USA.
authors.forename: Xiaodan
authors.initials: X
authors.lastname: Su
authors.forename: Chen
authors.initials: C
authors.lastname: Ren
authors.forename: Michael A
authors.initials: MA
authors.lastname: Freitas
mesh_terms: D006657:Histones / Q000032:analysis* / Q000737:chemistry; D013058:Mass Spectrometry / Q000379:methods*; D011499:Protein Processing, Post-Translational; D040901:Proteomics / Q000379:methods
chemical_list: D006657:Histones