title: Late stent thrombosis associated with coronary aneurysm formation after sirolimus-eluting stent implantation.
abstract: Stent thrombosis is a rare but potentially fatal complication of coronary stent implantation. Its occurrence late after drug-eluting stent (DES) deployment has led to concerns regarding their long-term safety. We report a case of late stent thrombosis 26 months after sirolimus-eluting stent (SES) (Cypher, Cordis Corp., Miami, Florida) implantation. This was associated with marked positive vessel remodeling and coronary aneurysm formation involving the stented segment of the coronary artery. The patient was on dual antiplatelet therapy at the time.
authors.affiliation: Department of Cardiology, Royal Blackburn Hospital, Blackburn, United Kingdom. saziz1@btinternet.com
authors.forename: Shahid
authors.initials: S
authors.lastname: Aziz
authors.forename: John L
authors.initials: JL
authors.lastname: Morris
authors.forename: Raphael A
authors.initials: RA
authors.lastname: Perry
mesh_terms: D000368:Aged; D015906:Angioplasty, Balloon, Coronary; D003323:Coronary Aneurysm / Q000209:etiology* / Q000503:physiopathology; D017023:Coronary Angiography; D003328:Coronary Thrombosis / Q000209:etiology* / Q000503:physiopathology; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage; D009203:Myocardial Infarction / Q000209:etiology / Q000628:therapy; D012008:Recurrence; D019233:Retreatment; D020123:Sirolimus / Q000008:administration & dosage; D015607:Stents / Q000009:adverse effects*; D013997:Time Factors
chemical_list: D007166:Immunosuppressive Agents; D020123:Sirolimus