title: Facts and controversies about radiation exposure, part 2: low-level exposures and cancer risk.
abstract: In this 2-part article, the authors address the need to put in perspective the risks of radiation exposure in the rapidly changing field of radiology, considering the current state of knowledge of effects at low levels. The article is based on the content of the refresher course RC 516 presented at the Radiological Society of North America's 2005 annual meeting. In part 1, the authors presented a brief review of epidemiologic studies, a discussion of typical radiation doses experienced in medicine by both patients and professionals, and the description of practical approaches to reduce unnecessary exposures. Part 2 addresses a special concern for the unborn and discusses advisory and regulatory cancer risk estimates based mainly on epidemiologic studies. The limitations of epidemiologic studies at low-level exposures and recent new findings in radiobiology, some of which are summarized, challenge the notion that any amount of radiation causes adverse effects.
authors.affiliation: Department of Radiology, University of Colorado at Denver Health Sciences Center, Denver, CO, USA.
authors.forename: Jadwiga Jodi
authors.initials: JJ
authors.lastname: Strzelczyk
authors.forename: John
authors.initials: J
authors.lastname: Damilakis
authors.forename: M Victoria
authors.initials: MV
authors.lastname: Marx
authors.forename: Katarzyna J
authors.initials: KJ
authors.lastname: Macura
mesh_terms: D000016:Abnormalities, Radiation-Induced / Q000453:epidemiology / Q000517:prevention & control*; D003952:Diagnostic Imaging / Q000009:adverse effects* / Q000379:methods; D004307:Dose-Response Relationship, Radiation; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D008297:Male; D009381:Neoplasms, Radiation-Induced / Q000453:epidemiology / Q000517:prevention & control*; D016272:Occupational Health; D011247:Pregnancy; D011829:Radiation Dosage; D011832:Radiation Injuries / Q000517:prevention & control*; D011834:Radiation Monitoring; D011835:Radiation Protection / Q000379:methods*; D011853:Radiobiology; D011878:Radiotherapy / Q000009:adverse effects / Q000379:methods; D018570:Risk Assessment