Myxoinflammatory fibroblastic sarcoma: report of a case with fine needle aspiration cytology.
BACKGROUND
Myxoinflammatory fibroblastic sarcoma (MFS) is a distinct neoplasm that usually arises in the acral zones of distalextremities. We report, for the first time, the preoperative fine needle a,spiration cytology (FNAC) findings of an MFS case that was confirmed after surgical excision.


METHODS
An 81-year-old woman presented with a multinodular tumor in the distal right extremity that had been present for 1 year. FNA C of the lesion was performed and followed by local excision. The fine needle aspiration smears contained 2 of the 3 types of neoplastic cells that have been observed in MFS: spindled and ganglionlike cells. The background was myxoid, with a prominent inflammatory infiltrate. Histopathologic examination of the surgical specimen confirmed the diagnosis of MFS.


CONCLUSIONS
Although the cytologic diagnosis was "pleomorphic sarcoma," MFS was considered and local excision recommended, given the reported low grade nature of this entity. However, the need for extreme caution in the diagnosis of soft tissue lesions on cytologic grounds alone cannot be overemphasized.
García-García
Elena
E
Department of Pathology, 12 de Octubre University Hospital, Madrid, Spain.
Rodríguez-Gil
Yolanda
Y
Suárez-Gauthier
Ana
A
Martínez-Tello
Francisco José
FJ
López-Ríos
Fernando
F
Ballestín
Claudio
C
D000369:Aged, 80 and over; D015703:Antigens, CD / Q000032:analysis / Q000378:metabolism; D015214:Antigens, Differentiation, Myelomonocytic / Q000032:analysis / Q000378:metabolism; D014408:Biomarkers, Tumor / Q000032:analysis / Q000378:metabolism; D044963:Biopsy, Fine-Needle; D017675:CREST Syndrome / Q000150:complications; D002467:Cell Nucleus / Q000473:pathology; D003593:Cytoplasm / Q000473:pathology; D003937:Diagnosis, Differential; D005260:Female; D005347:Fibroblasts / Q000473:pathology*; D006801:Humans; D007866:Leg / Q000473:pathology* / Q000503:physiopathology / Q000601:surgery; D009236:Myxosarcoma / Q000473:pathology* / Q000503:physiopathology / Q000601:surgery; D009361:Neoplasm Invasiveness / Q000503:physiopathology; D009362:Neoplasm Metastasis / Q000503:physiopathology; D019637:Orthopedic Procedures; D011237:Predictive Value of Tests; D012509:Sarcoma / Q000473:pathology* / Q000503:physiopathology / Q000601:surgery; D016896:Treatment Outcome; D014746:Vimentin / Q000032:analysis / Q000378:metabolism; D000097382:CD68 Molecule
D015703:Antigens, CD; D015214:Antigens, Differentiation, Myelomonocytic; D014408:Biomarkers, Tumor; D014746:Vimentin; C067980:CD68 antigen, human; D000097382:CD68 Molecule