Biosynthesis of rutacridone: the N-methylation step.
The N-methylation of rutacridone was investigated. This dihydrofuroacridone derivative ist the main alkaloid in cell suspension cultures of RUTA GRAVEOLENS, strain R-20. The N-methyl group is provided by L-methionine. N-methylanthranilic acid serves as excellent precursor of rutacridone. Furthermore this particular precursor could be trapped after feeding anthranilic acid in short term experiments.
Baumert
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Institut für Biochemie der Pflanzen, Akademie der Wissenschaften der DDR, Halle (Saale), DDR.
Kuzovkina
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IN
Hieke
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M
Gröger
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D