Pneumocystis pneumonia in a patient with non-small cell lung cancer (NSCLC) treated with pemetrexed containing regimen.
Pneumocystis pneumonia is typically life-threatening in immunocompromised patients. It is relatively uncommon in patients with lung cancer. We report a case of pneumocystis pneumonia in a patient with advanced stage non-small cell lung cancer (NSCLC) following treatment with concurrent chemoradiation with a pemetrexed containing regimen. To our knowledge, this is the first report on pneumocystis pneumonia following administration of pemetrexed containing regimen.
Velcheti
Vamsidhar
V
Department of Medicine, Washington University School of Medicine, St. Louis, MO, United States.
Govindan
Ramaswamy
R
D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000964:Antimetabolites, Antineoplastic / Q000627:therapeutic use*; D001999:Bronchoscopy; D002289:Carcinoma, Non-Small-Cell Lung / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000532:radiotherapy; D017809:Fatal Outcome; D005971:Glutamates / Q000627:therapeutic use*; D006147:Guanine / Q000031:analogs & derivatives* / Q000627:therapeutic use; D006801:Humans; D007770:L-Lactate Dehydrogenase / Q000097:blood; D008175:Lung Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000532:radiotherapy; D008297:Male; D000068437:Pemetrexed; D011020:Pneumonia, Pneumocystis / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy / Q000601:surgery; D011859:Radiography
D000900:Anti-Bacterial Agents; D000964:Antimetabolites, Antineoplastic; D005971:Glutamates; D000068437:Pemetrexed; D006147:Guanine; D007770:L-Lactate Dehydrogenase