Decreased human milk concentration of epidermal growth factor after preterm delivery of intrauterine growth-restricted newborns.
OBJECTIVE
The aim of the study was to compare epidermal growth factor (EGF) concentration in 81 colostrum samples collected from mothers of newborns in the following growth categories: preterm appropriate for gestational age (AGA), preterm small for gestational age (SGA), and full term (FT).


RESULTS
Significantly higher concentrations of EGF were found in the colostrum of mothers who delivered premature AGA infants at less than 32 weeks of gestation compared with mothers who delivered premature SGA babies at the same gestational age.


CONCLUSIONS
We concluded that the maternal compensatory mechanism accelerating the development of immature breast-fed infants may be disturbed when gestation is complicated by intrauterine growth retardation.
Oslislo
Anna
A
Department of Perinatology and Gynecology, Medical University of Silesia, Zabrze, Poland. aoslislo@o2.pl
Czuba
Zenon
Z
Sławska
Helena
H
Kaźmierczak
Wojciech
W
Król
Wojciech
W
D001724:Birth Weight; D003126:Colostrum / Q000737:chemistry*; D004815:Epidermal Growth Factor / Q000032:analysis*; D005260:Female; D005317:Fetal Growth Retardation; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D007236:Infant, Small for Gestational Age; D008895:Milk, Human / Q000737:chemistry*; D011247:Pregnancy; D047928:Premature Birth; D047929:Term Birth
D004815:Epidermal Growth Factor