title: Research and events leading to facial transplantation.
abstract: Facial transplantation has long captured the interest and imagination of scientists, the media, and the lay public. Facial transplantation could provide an excellent alternative to current treatments for facial disfigurement caused by burns, trauma, cancer extirpation, or congenital birth defects. This article discusses the major technical, immunologic, psychosocial and ethical hurdles that have been overcome to bring facial transplantation from an idea to a clinical reality by providing the reader with a chronologic overview of the research and events that have led this exciting new treatment into the clinical arena.
authors.affiliation: Department of Surgery, 511 South Floyd Street, 320 MDR Building, University of Louisville, Louisville, KY 40202, USA. jhbark01@louisville.edu
authors.forename: John H
authors.initials: JH
authors.lastname: Barker
authors.forename: Niki
authors.initials: N
authors.lastname: Stamos
authors.forename: Allen
authors.initials: A
authors.lastname: Furr
authors.forename: Sean
authors.initials: S
authors.lastname: McGuire
authors.forename: Michael
authors.initials: M
authors.lastname: Cunningham
authors.forename: Osborne
authors.initials: O
authors.lastname: Wiggins
authors.forename: Charles S
authors.initials: CS
authors.lastname: Brown
authors.forename: Brian
authors.initials: B
authors.lastname: Gander
authors.forename: Claudio
authors.initials: C
authors.lastname: Maldonado
authors.forename: Joseph C
authors.initials: JC
authors.lastname: Banis
mesh_terms: D000208:Acute Disease; D026690:Ethics, Clinical; D005151:Facial Injuries / Q000601:surgery*; D006084:Graft Rejection / Q000517:prevention & control; D049673:History, 20th Century; D049674:History, 21st Century; D006789:Host vs Graft Reaction; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D019651:Plastic Surgery Procedures / Q000266:history* / Q000379:methods*; D014184:Transplantation, Homologous / Q000266:history* / Q000379:methods*
chemical_list: D007166:Immunosuppressive Agents