title: Epigenetics and microRNAs.
abstract: MicroRNAs (miRNAs) regulate protein-coding genes post transcriptionally in higher eukaryotes. Argonaute proteins are important in miRNA regulation and are also implicated in epigenetic mechanisms such as histone modifications and DNA methylation. Here, we review miRNA regulation and outline its connections to epigenetics.
authors.affiliation: Division of Molecular Biology, Beckman Research Institute of the City of Hope, Duarte, CA 91010, USA.
authors.forename: Pål
authors.initials: P
authors.lastname: Saetrom
authors.forename: Ola
authors.initials: O
authors.lastname: Snøve
authors.forename: John J
authors.initials: JJ
authors.lastname: Rossi
mesh_terms: D000818:Animals; D044127:Epigenesis, Genetic; D005786:Gene Expression Regulation; D006801:Humans; D035683:MicroRNAs / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D009690:Nucleic Acid Conformation; D016601:RNA-Binding Proteins / Q000235:genetics / Q000378:metabolism
chemical_list: D035683:MicroRNAs; D016601:RNA-Binding Proteins