Phenalenone-type compounds from Musa acuminata var. "Yangambi km 5" (AAA) and their activity against Mycosphaerella fijiensis.
Two perinaphthenone-type compounds (1 and 2) were isolated together with four known phenylphenalenones (3-6) from the rhizomes of Musa acuminata var. "Yangambi km 5". The structures of the new phenalenones were assigned as 2-hydroxy-1H-phenalen-1-one (1) and 2-methoxy-1H-phenalen-1-one (2) on the basis of their spectroscopic data and were confirmed by synthesis. Compounds 1 and 2 displayed significantly enhanced activity against Mycosphaerella fijiensis in comparison with other phenylphenalenones.
Otálvaro
Felipe
F
Departamento de Ingeniería, Universidad Nacional de Colombia sede Palmira, Carrera 32 Chapinero vía Candelaria, A.A 237, Palmira-Valle del Cauca, Colombia. lfotalvarot@palmira.unal.edu.co
Nanclares
Juliana
J
Vásquez
Luz Estella
LE
Quiñones
Winston
W
Echeverri
Fernando
F
Arango
Rafael
R
Schneider
Bernd
B
D000935:Antifungal Agents / Q000737:chemistry* / Q000494:pharmacology*; D001203:Ascomycota / Q000187:drug effects*; D015394:Molecular Structure; D028521:Musa / Q000737:chemistry*; D043803:Phenalenes / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology*; D010946:Plants, Medicinal / Q000737:chemistry*; D027343:Rhizome / Q000737:chemistry
D000935:Antifungal Agents; D043803:Phenalenes; C038036:phenalen-1-one