title: Solid organ transplantation at the National Institutes of Health: development of a research-based transplantation practice.
abstract: The National Institutes of Health has established a clinical transplant research program focusing on translational research in kidney transplantation. The program has been developed with a multidisciplinary approach under a common administrative structure that integrates transplant physicians and surgeons with clinical laboratory and data analysis support personnel. The program has achieved excellent clinical outcomes despite focusing exclusively on investigational methods and serving a diverse and medically complex patient population. Novel approaches toward consenting, computer integration, and tissue acquisition have been layered over interventional and observational studies to serve the scientific mission while delivering quality transplant care.
authors.affiliation: The Transplantation Branch, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) and The Laboratory of Pathology, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
authors.forename: Allan D
authors.initials: AD
authors.lastname: Kirk
authors.forename: Douglas A
authors.initials: DA
authors.lastname: Hale
authors.forename: Elizabeth
authors.initials: E
authors.lastname: Ford
authors.forename: David E
authors.initials: DE
authors.lastname: Kleiner
authors.forename: Robert L
authors.initials: RL
authors.lastname: Kampen
authors.forename: Eric A
authors.initials: EA
authors.lastname: Elster
authors.forename: S John
authors.initials: SJ
authors.lastname: Swanson
authors.forename: Linda C
authors.initials: LC
authors.lastname: Cendales
authors.forename: Tracy
authors.initials: T
authors.lastname: Cropper
authors.forename: Liz
authors.initials: L
authors.lastname: Hale
authors.forename: Susan
authors.initials: S
authors.lastname: Jordan
authors.forename: Trish
authors.initials: T
authors.lastname: Koussis
authors.forename: Julie
authors.initials: J
authors.lastname: Peretti
authors.forename: Anne
authors.initials: A
authors.lastname: Sloane
authors.forename: Christine
authors.initials: C
authors.lastname: Salaita
authors.forename: Michael
authors.initials: M
authors.lastname: Ring
authors.forename: Christine
authors.initials: C
authors.lastname: Chamberlain
authors.forename: Roslyn B
authors.initials: RB
authors.lastname: Mannon
mesh_terms: D005260:Female; D006801:Humans; D007165:Immunosuppression Therapy; D016030:Kidney Transplantation / Q000276:immunology / Q000706:statistics & numerical data; D008297:Male; D008991:Monitoring, Physiologic; D009316:National Institutes of Health (U.S.); D016377:Organ Transplantation / Q000523:psychology / Q000706:statistics & numerical data*; D018579:Patient Selection; D011184:Postoperative Period; D044469:Racial Groups; D012984:Software; D009927:Tissue and Organ Procurement / Q000458:organization & administration; D014481:United States