title: Frequency domain analysis of human subdural recordings.
abstract: It is possible to localize many aspects of cortical function and dysfunction without the use of direct electrical stimulation of cortex. This study explores the degree to which information can be obtained about functional cortical organization relative to epileptogenic regions through analysis of electrocorticographic recordings in the frequency domain. Information about the extent of seizure regions and the location of the normal sensory and motor homunculus and some higher language and memory related areas can be obtained through the analysis of task-related power spectrum changes and changes in lateral interelectrode coherence patterns calculated from interictal and ictal recordings.
authors.affiliation: Department of Neurology, The University of Chicago, Chicago, Illinois 60637, USA. vtowle@neurology.bsd.uchicago.edu
authors.forename: Vernon L
authors.initials: VL
authors.lastname: Towle
authors.forename: John D
authors.initials: JD
authors.lastname: Hunter
authors.forename: J Christopher
authors.initials: JC
authors.lastname: Edgar
authors.forename: Sozari A
authors.initials: SA
authors.lastname: Chkhenkeli
authors.forename: Michael C
authors.initials: MC
authors.lastname: Castelle
authors.forename: David M
authors.initials: DM
authors.lastname: Frim
authors.forename: Michael
authors.initials: M
authors.lastname: Kohrman
authors.forename: Kurt E
authors.initials: KE
authors.lastname: Hecox
mesh_terms: D000293:Adolescent; D000328:Adult; D001931:Brain Mapping; D002648:Child; D004566:Electrodes; D004569:Electroencephalography / Q000379:methods; D004827:Epilepsy / Q000473:pathology* / Q000503:physiopathology*; D006801:Humans; D021621:Imaging, Three-Dimensional; D008279:Magnetic Resonance Imaging / Q000379:methods; D013057:Spectrum Analysis; D013355:Subdural Space / Q000503:physiopathology*; D013997:Time Factors