title: Consumption of herbal remedies and dietary supplements amongst patients hospitalized in medical wards.
abstract: OBJECTIVE
  Herbal remedies may have adverse effects and potentially serious interactions with some commonly prescribed conventional medications. Little is known about consumption of herbal remedies and dietary supplements by hospitalized patients. The aim was to evaluate the rate of consumption and characterize the patients hospitalized in internal medicine departments who consume herbal remedies and dietary supplements. Also, to assess the medical teams' awareness and assess the percentage of patients with possible drug-herb interactions.
  
  
  METHODS
  Patients hospitalized in the medical wards of two hospitals in Israel were interviewed about their use of herbal remedies or dietary supplements. The medical records were searched for evidence that the medical team had knowledge of the use of herbal remedies or dietary supplements.
  
  
  RESULTS
  Two hundred and ninety-nine hospitalized medical patients were interviewed. Of the participants, 26.8% were herbal or dietary supplement consumers (HC). On multivariate analysis the only variates associated with herbal or dietary supplement consumption were the hospital [odds ratio (OR) 2.97, 95% confidence interval (CI) 1.29, 6.52], income (OR 0.39, 95% CI 0.15, 1.05), smoking habits (OR 0.17, 95% CI 0.05, 0.55) and benign prostatic hypertrophy (OR 4.64, 95% CI 1.3, 16.5). Ninety-four percent of the patients had not been asked specifically of herbal consumption by the medical team. Only 23% of the hospital's medical files of the HC patients had any record of the use of herbal or dietary supplements. Seven possible drug-herbal interactions were encountered (7.1%). The most serious was an interaction between camomile tea and ciclosporin.
  
  
  CONCLUSIONS
  Herbal remedy consumption is common amongst patients hospitalized in internal medicine wards and is often overlooked by the medical team. Patients and doctors should be more aware of the possible adverse effects and of the potential of herb-drug interactions.
authors.affiliation: Clinical Pharmacology and Toxicology Unit, Assaf Harofeh Medical Centre, Zerrifin, Affiliated to the Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel. leeg@asaf.health.gov.il
authors.forename: Lee H
authors.initials: LH
authors.lastname: Goldstein
authors.forename: Mazen
authors.initials: M
authors.lastname: Elias
authors.forename: Gilat
authors.initials: G
authors.lastname: Ron-Avraham
authors.forename: Ben Zion
authors.initials: BZ
authors.lastname: Biniaurishvili
authors.forename: Magali
authors.initials: M
authors.lastname: Madjar
authors.forename: Irena
authors.initials: I
authors.lastname: Kamargash
authors.forename: Rony
authors.initials: R
authors.lastname: Braunstein
authors.forename: Matitiahu
authors.initials: M
authors.lastname: Berkovitch
authors.forename: Ahuva
authors.initials: A
authors.lastname: Golik
mesh_terms: D001291:Attitude of Health Personnel; D019587:Dietary Supplements / Q000706:statistics & numerical data*; D036262:Empirical Research; D005260:Female; D041743:Herb-Drug Interactions; D006801:Humans; D007297:Inpatients / Q000523:psychology*; D007388:Internal Medicine; D007557:Israel; D008297:Male; D008875:Middle Aged; D008517:Phytotherapy / Q000706:statistics & numerical data*