Abnormal sudomotor skin responses to temperature and pain stimuli in syringomyelia.
Thermoalgesic sensory deficits in patients with syringomyelia may escape objective documentation with conventional electrophysiological techniques. We examined six patients with radiologically proven centrospinal cavities and patchy thermoalgesic sensory deficits by recording the evoked potentials and the sympathetic sudomotor skin responses (SSR) to laser stimuli. While electrical stimuli to the affected areas induced evoked potentials and SSRs of normal latency and amplitude, CO2 laser stimulation induced absent or abnormally reduced evoked potentials. Also, warmth and heat pain stimulation with a Peltier thermode induced absent or abnormal SSRs when applied over the affected areas but well defined SSRs when applied to the corresponding contralateral areas. Our results reveal the utility of recording the SSR to pain and temperature stimuli over specific body sites to demonstrate impairment of pain and temperature pathways in patients with syringomyelia. Comparison of electrical versus laser and temperature induced SSRs is an objective means to evaluate the selective thermoalgesic sensory deficit in these patients.
Veciana
M
M
Dept. of Neurology, Hospital de St Boi, Barcelona, Spain.
Valls-Solé
J
J
Schestatsky
P
P
Montero
J
J
Casado
V
V
D000328:Adult; D000368:Aged; D005071:Evoked Potentials / Q000502:physiology / Q000528:radiation effects; D005073:Evoked Potentials, Somatosensory / Q000502:physiology / Q000528:radiation effects; D005260:Female; D007839:Functional Laterality; D006801:Humans; D007834:Lasers / Q000009:adverse effects; D008297:Male; D008875:Middle Aged; D010146:Pain; D010147:Pain Measurement; D011930:Reaction Time / Q000502:physiology; D012867:Skin / Q000294:innervation* / Q000503:physiopathology; D018709:Statistics, Nonparametric; D013595:Syringomyelia / Q000503:physiopathology*; D013697:Thermosensing / Q000502:physiology*