title: [Sweet's syndrome: a propos of 8 cases].
abstract: BACKGROUND
  Sweet's syndrome is a dermatosis classically determined by painful erythematous plaques or nodules associated with fever, neutrophilia and dense neutrophilic dermal infiltrate. In most cases, Sweet's syndrome may occur in the absence of other diseases. However, it can be associated with an inflammatory disease and essentially with malignant conditions in 20% of cases requiring a careful investigation.
  
  
  OBJECTIVE
  We report herein, the epidemiological, clinical, therapeutic and evolutive features of a hospital serie.
  
  
  METHODS
  We retrospectively reviewed all the files of patients conforming with the diagnosis of SS, seen at the dermatology departement of Habib Thameur hospital during a 7-year period (from 1997 to 2003). All patients fulfilled at least two major criteria and two minor criteria of Su et Liu's diagnostic criteria modified by Von Den Driesch.
  
  
  RESULTS
  8 cases of .Sweet's syndrome were diagnosed. All patients were females. The mean age was 51.62 years. The lesions occurred on the upper limbs in 7/8 cases. SS was isolated in 6 cases and para-inflammatory in one case corresponding to an associated Sjogren's syndrome. Besides the standard therapy using oral corticosteroids (3 patients), non steroidal inflammatory agents has been efficient in 4 cases.
  
  
  CONCLUSIONS
  In our serie, we report an exclusive female involvement and a lower frequency of associated diseases compared with the relevant literature. Association of SS and Sjogren's syndrome is exceptional. To our knowledge, only 6 cases have already been reported.
authors.affiliation: Service de Dermatologie, Hôpital Habib Thameur, Tunis, Tunisie.
authors.forename: Amel
authors.initials: A
authors.lastname: Souissi
authors.forename: Rym
authors.initials: R
authors.lastname: Benmously
authors.forename: Sami
authors.initials: S
authors.lastname: Fenniche
authors.forename: Mohamed
authors.initials: M
authors.lastname: Zarrouk
authors.forename: Hayet
authors.initials: H
authors.lastname: Marrek
authors.forename: Achraf
authors.initials: A
authors.lastname: Debbiche
authors.forename: Mohamed Ben
authors.initials: MB
authors.lastname: Ayed
authors.forename: Inçaf
authors.initials: I
authors.lastname: Mokhtar
mesh_terms: D000284:Administration, Oral; D000305:Adrenal Cortex Hormones / Q000008:administration & dosage / Q000627:therapeutic use; D000328:Adult; D000367:Age Factors; D000368:Aged; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage / Q000627:therapeutic use; D001706:Biopsy; D005260:Female; D006801:Humans; D007213:Indomethacin / Q000008:administration & dosage / Q000627:therapeutic use; D008875:Middle Aged; D009544:Niflumic Acid / Q000008:administration & dosage / Q000627:therapeutic use; D012189:Retrospective Studies; D012737:Sex Factors; D012859:Sjogren's Syndrome / Q000150:complications; D012867:Skin / Q000473:pathology; D016463:Sweet Syndrome / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology / Q000473:pathology; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D000305:Adrenal Cortex Hormones; D000894:Anti-Inflammatory Agents, Non-Steroidal; D009544:Niflumic Acid; D007213:Indomethacin