title: Screening preferences of patients at familial risk of colorectal cancer.
abstract: Our primary objective was to assess the screening preferences of patients at familial risk of colorectal cancer. Asymptomatic subjects aged 18-75 with a single first-degree relative diagnosed with colorectal cancer (n = 48) or polyps (n = 52) were asked to identify a preferred screening strategy, test features influencing their choice, and level of interest in decision-making after reviewing a decision aid describing the pros and cons of currently recommended screening tests. Although both groups preferred colonoscopy, 40% of subjects with a family history of colorectal cancer and 48% of those with a family history of polyps preferred alternative strategies. Accuracy was the most commonly identified test feature influencing test preference. Most subjects (66%) felt that selection of screening test should be a patient dominant or shared process. We conclude that patients at familial risk of colorectal cancer have distinct screening preferences that often vary from current recommendations.
authors.affiliation: Department of Medicine, Boston University School of Medicine, Boston, MA, USA. paul.schroy@bmc.org
authors.forename: Paul C
authors.initials: PC
authors.lastname: Schroy Iii
authors.forename: Julie T
authors.initials: JT
authors.lastname: Glick
authors.forename: Patricia A
authors.initials: PA
authors.lastname: Robinson
authors.forename: Timothy
authors.initials: T
authors.lastname: Heeren
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D003113:Colonoscopy / Q000379:methods*; D015179:Colorectal Neoplasms / Q000175:diagnosis* / Q000453:epidemiology / Q000235:genetics; D003430:Cross-Sectional Studies; D005260:Female; D020022:Genetic Predisposition to Disease; D006801:Humans; D008297:Male; D008403:Mass Screening / Q000379:methods*; D008404:Massachusetts / Q000453:epidemiology; D008875:Middle Aged; D016017:Odds Ratio; D017060:Patient Satisfaction; D015995:Prevalence; D012307:Risk Factors