title: Systemic metastasis following hyphema drainage in an unsuspected retinoblastoma.
abstract: A 6-year-old girl had total hyphema and elevated left intraocular pressure following trivial trauma. B-scan with vector A-scan revealed vitreous opacities consistent with hemorrhage. The drained hyphema did not recur. A left vascular conjunctival mass and massive cervical lymphadenopathy occurred 7 months later. Biopsy revealed extraocular retinoblastoma and lymph node metastasis. Computed tomography showed an intraocular mass with intracranial extension. She died of metastatic disease despite intensive chemotherapy. Retinoblastoma should be suspected in a child with hyphema following trivial trauma.
authors.affiliation: Ocular Oncology Service, LVPrasad Eye Institute, Hyderabad, India.
authors.forename: Ramesh
authors.initials: R
authors.lastname: Murthy
authors.forename: Santosh G
authors.initials: SG
authors.lastname: Honavar
authors.forename: Geeta K
authors.initials: GK
authors.lastname: Vemuganti
authors.forename: Milind N
authors.initials: MN
authors.lastname: Naik
authors.forename: Vijayanand P
authors.initials: VP
authors.lastname: Reddy
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001932:Brain Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary*; D002114:Calcinosis / Q000000981:diagnostic imaging / Q000209:etiology; D002648:Child; D003230:Conjunctival Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary*; D004322:Drainage; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D006988:Hyphema / Q000601:surgery*; D007429:Intraocular Pressure; D008207:Lymphatic Metastasis; D019572:Retinal Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D012175:Retinoblastoma / Q000000981:diagnostic imaging / Q000556:secondary*; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography