Evidence for the rapid conversion of stephacidin B into the electrophilic monomer avrainvillamide in cell culture.
Wulff
Jeremy E
JE
Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts 02138, USA.
Herzon
Seth B
SB
Siegrist
Romain
R
Myers
Andrew G
AG
D049109:Cell Proliferation / Q000187:drug effects*; D003545:Cysteine / Q000032:analysis; D006801:Humans; D026121:Indole Alkaloids / Q000737:chemistry / Q000378:metabolism* / Q000494:pharmacology*; D007211:Indoles / Q000737:chemistry / Q000378:metabolism* / Q000494:pharmacology*; D009363:Neoplasm Proteins / Q000378:metabolism; D009369:Neoplasms / Q000378:metabolism; D014407:Tumor Cells, Cultured
D026121:Indole Alkaloids; D007211:Indoles; D009363:Neoplasm Proteins; C480558:avrainvillamide; C470894:stephacidin B; D003545:Cysteine