title: Decrease in prevalence of peptic ulcer and gastric adenocarcinoma at the Policlínico Peruano Japones, Lima, Peru, between the years 1985 and 2002. Analysis of 31,446 patients.
abstract: OBJECTIVE
  To determine the prevalence of peptic ulcer and gastric adenocarcinoma in a population of middle and high socio-economic status in Lima, Peru, between 1985 and 2002.
  
  
  METHODS
  The prevalence of gastroduodenal ulcer and gastric adenocarcinoma was determined after studying by esophagogastroduodenoscopy 31,446 patients at the Policlínico Peruano Japonds (PPJ) between 1985 and 2002. All patients had chronic upper gastrointestinal symptoms and had endoscopically proven diagnosis of active peptic ulcer or histological diagnosis of gastric adenocarcinoma.
  
  
  RESULTS
  Analysis of PPJ population identified a decrease in the prevalence of gastric ulcer and duodenal ulcer from 3.15% and 5.05% respectively in 1985, to 1.62% and 2.00% respectively in 2002. Gastric adenocarcinoma prevalence also decreased from 3.19% in 1988 to 0.92% in 2002. The prevalences of gastric ulcer (OR = 1.49, 95% IC 1.26-1.77, p < 0.001), duodenal ulcer (OR = 1.32, 95% IC 1.15-1.51, p < 0.001) and gastric adenocarcinoma (OR = 1.53, 95% IC 1.25-1.86, p < 0.001), decreased in the last eight years.
  
  
  CONCLUSIONS
  Over the study period, there was a significant decrease in the prevalence of peptic ulcer and gastric adenocarcinoma at the Policlinico Peruano Japonés, where patients from middle and high socio economic status are attended.
authors.affiliation: Universidad Peruana Cayetano Heredia, Lima, Perú. ramirezramosicaza@yahoo.com
authors.forename: Alberto
authors.initials: A
authors.lastname: Ramírez-Ramos
authors.forename: José
authors.initials: J
authors.lastname: Watanabe-Yamamoto
authors.forename: Juan
authors.initials: J
authors.lastname: Takano-Morón
authors.forename: Robert H
authors.initials: RH
authors.lastname: Gilman
authors.forename: Sixto
authors.initials: S
authors.lastname: Recavarren Arce
authors.forename: Javier
authors.initials: J
authors.lastname: Arias-Stella
authors.forename: Elena
authors.initials: E
authors.lastname: Yoshiwara-Wakabayashi
authors.forename: Carlos
authors.initials: C
authors.lastname: Rodríguez-Ulloa
authors.forename: Juan
authors.initials: J
authors.lastname: Miyagui-Maeda
authors.forename: Erick
authors.initials: E
authors.lastname: Chinga-Alayo
authors.forename: Daniel
authors.initials: D
authors.lastname: Mendoza-Requena
authors.forename: Julio
authors.initials: J
authors.lastname: Leey-Casella
authors.forename: Angel
authors.initials: A
authors.lastname: Rosas-Aguirre
authors.forename: Billie
authors.initials: B
authors.lastname: Velapatiño-Cochachi
authors.forename: Daniel
authors.initials: D
authors.lastname: Guerra Valencia
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis / Q000453:epidemiology*; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003430:Cross-Sectional Studies; D004381:Duodenal Ulcer / Q000453:epidemiology; D016145:Endoscopy, Digestive System; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010437:Peptic Ulcer / Q000175:diagnosis / Q000453:epidemiology*; D010568:Peru / Q000453:epidemiology; D015995:Prevalence; D017678:Sex Distribution; D012923:Social Class; D013274:Stomach Neoplasms / Q000175:diagnosis / Q000453:epidemiology*; D013276:Stomach Ulcer / Q000175:diagnosis / Q000453:epidemiology