Oxidants and ocular tumors.
Serum superoxide dismutase and catalase assays were performed using spectrophotometry in 60 adults and children with benign or malignant tumors and in controls. There was a statistically significant difference in the antioxidative status of children with intraocular tumors (primary retinoblastoma) compared with children without tumors. The difference was not significant in adults. These enzymes may be of value in the early diagnosis of malignant intraocular tumor, especially retinoblastoma.
Singh
Rajendra
R
Department of Opthalmology, Institute of Medical Sciences, Banaras Hindu University, India. RJFugomd@fugoblade.com
Chattopadhyay
Abhijit
A
Agarwal
Alka
A
Bhattacharya
S K
SK
Bhattacharya
A K
AK
D000328:Adult; D000367:Age Factors; D002374:Catalase / Q000097:blood; D002648:Child; D005134:Eye Neoplasms / Q000201:enzymology / Q000209:etiology* / Q000378:metabolism; D005260:Female; D006801:Humans; D008297:Male; D016877:Oxidants / Q000378:metabolism*; D018384:Oxidative Stress; D012175:Retinoblastoma / Q000201:enzymology / Q000209:etiology* / Q000378:metabolism; D013482:Superoxide Dismutase / Q000097:blood
D016877:Oxidants; D002374:Catalase; D013482:Superoxide Dismutase