Solitary intracranial Castleman's disease, plasma cell variant: a case report.
OBJECTIVE
We report a case of plasma cell variant of Castleman's disease confined to the meninges.


METHODS
A 53-year-old woman presented with severe headache lasting a few months, which was insidious in onset but followed a progressive course with associated vomiting, blurring of vision and diplopia. Investigations revealed a dural-based mass that was considered both radiologically and intraoperatively as a meningioma. Total surgical excision of the mass was performed. Histologically, it was a plasma cell variant of Castleman's disease with kappa light chain restriction. Laboratory investigations and whole body computerized tomography scan showed no significant abnormality. A short course of local radiotherapy was given. The patient is well 2 years after treatment.


CONCLUSIONS
This report highlights the rarity of solitary intracranial Castleman's disease and the difficulty in radiological and intraoperative diagnosis.
Mallik
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Department of Pathology, Al-Sabah Hospital, Safat, Kuwait. anupamamallik@yahoo.co.in
Katchy
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KC
Clotan
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D005871:Castleman Disease / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D003131:Combined Modality Therapy; D003287:Contrast Media; D003937:Diagnosis, Differential; D004388:Dura Mater / Q000473:pathology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D014057:Tomography, X-Ray Computed
D003287:Contrast Media