title: [The surgical treatment and prognosis of bilateral sporadic renal tumors].
abstract: OBJECTIVE
  To evaluate the surgical management and prognostic characteristics of bilateral sporadic renal tumors (BSRTs).
  
  
  METHODS
  Twenty-three cases of BSRTs were identified and retrospectively reviewed. The presenting clinical findings, surgical treatment, and prognosis were evaluated.
  
  
  RESULTS
  Twelve patients had synchronous tumors and 11 had asynchronous tumors. BSRTs comprised 1.8% of all RCC cases with a male-to-female ratio of 6.67:1 in the same term. The mean age of patients was 56 years. Seventeen patients were preformed bilateral operation (10 had synchronous and 7 had asynchronous tumors), 4 patients were preformed unilateral operation (1 had synchronous and 3 had asynchronous tumors), and 2 patients were not performed operation (asynchronous tumors). Twenty-one patients were followed up (11 had synchronous tumors and 10 had asynchronous tumors, mean 27 months). One and 5-years cancer specific survival rate of BSRTs were 84.6% and 33.5% respectively. The rate of renal failure of synchronous BSRTs (18%) was lower than that of asynchronous BSRTs (70%) after operation (P=0.030).
  
  
  CONCLUSIONS
  Prognosis of BSRTs is poor. The key in the treatment of BSRTs is to detect and resect tumor earlier. Our results indicate that nephron sparing surgery should be performed in order to obtain optimal functional preservation of the renal remnant with complete local excision of tumor.
authors.affiliation: Department of Urology, the First Hospital of Peking University, Institute of Urology, Peking University, Beijing 100034, China.
authors.forename: Ning
authors.initials: N
authors.lastname: Zhang
authors.forename: Kan
authors.initials: K
authors.lastname: Gong
authors.forename: Li-qun
authors.initials: LQ
authors.lastname: Zhou
authors.forename: Yong
authors.initials: Y
authors.lastname: Yang
authors.forename: Yan-qun
authors.initials: YQ
authors.lastname: Na
mesh_terms: D000328:Adult; D000368:Aged; D002292:Carcinoma, Renal Cell / Q000473:pathology / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D053208:Kaplan-Meier Estimate; D007668:Kidney / Q000473:pathology / Q000601:surgery; D007680:Kidney Neoplasms / Q000473:pathology / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D009392:Nephrectomy / Q000379:methods*; D011379:Prognosis; D012189:Retrospective Studies; D016896:Treatment Outcome