title: Syntheses and structures of pyrazolylmethane complexes of rhenium(III), (IV) and (V).
abstract: Reaction of [ReOCl3(PPh3)(2)] with HCpz(3) (pz = pyrazole) in dichloromethane leads to the formation of a new Re(iv) complex [ReCl3(HCpz3)]X (X=Cl, [ReO4]) with loss of the rhenium-oxo group. We also report a convenient, high-yield synthetic route to complexes of the type [ReOXn(L)](3-n)+ (X=Cl, Br, n = 2, 3) by the reaction of bis(pyrazolylmethane) and bis(pyrazolylacetate) ligands with [ReOCl3(PPh3)2]. Dinuclear complexes containing the O=Re-O-Re=O group were also isolated and structurally characterised. We have also investigated the reactions of these ligands with diazenide precursors and isolated and characterised complexes of the type [ReClx(N2Ph) (L)(PPh3)] (x = 1,2). The potential applications of these complexes as radiopharmaeuticals is discussed.
authors.affiliation: Central Chemistry Department, University of Oxford, 12 Mansfield Road, Oxford, UK.
authors.forename: Andrew R
authors.initials: AR
authors.lastname: Cowley
authors.forename: Jonathan R
authors.initials: JR
authors.lastname: Dilworth
authors.forename: Maria
authors.initials: M
authors.lastname: Salichou
mesh_terms: D002627:Chemistry, Physical / Q000379:methods*; D002851:Chromatography, High Pressure Liquid; D018360:Crystallography, X-Ray; D019281:Dimerization; D004563:Electrochemistry / Q000379:methods; D008024:Ligands; D008697:Methane / Q000737:chemistry*; D008968:Molecular Conformation; D009942:Organometallic Compounds / Q000737:chemistry; D010100:Oxygen / Q000737:chemistry; D011720:Pyrazoles / Q000138:chemical synthesis / Q000737:chemistry*; D019275:Radiopharmaceuticals; D012211:Rhenium / Q000737:chemistry*; D013056:Spectrophotometry, Ultraviolet; D013997:Time Factors
chemical_list: D008024:Ligands; D009942:Organometallic Compounds; D011720:Pyrazoles; D019275:Radiopharmaceuticals; D012211:Rhenium; D008697:Methane; D010100:Oxygen