title: An unusual case of late bioprosthetic mitral valve thrombosis successfully managed with anticoagulation.
abstract: In this report, we present the case of a patient with hemodynamically significant thrombosis of a mitral bioprosthesis occurring 11 years after valve replacement. The diagnosis was suspected on the basis of a subacute increase in the transvalvular gradient seen on transthoracic echocardiography and was con- firmed by transesophageal echocardiography which disclosed unusual features. A hypercoagulable work up showed raised plasma factor VIII levels. The patient was successfully managed with oral anticoagulation.
authors.affiliation: Division of Cardiology, Tivoli University Hospital, Max Buset Avenue 34, 7100 La Louvière, Belgium. adaminian@hotmail.com
authors.forename: Adel
authors.initials: A
authors.lastname: Aminian
authors.forename: Pascal
authors.initials: P
authors.lastname: Lefebvre
authors.forename: Philippe
authors.initials: P
authors.lastname: Delmotte
authors.forename: Alain
authors.initials: A
authors.lastname: Friart
mesh_terms: D000368:Aged; D000925:Anticoagulants / Q000627:therapeutic use*; D001705:Bioprosthesis / Q000009:adverse effects*; D005260:Female; D006350:Heart Valve Prosthesis / Q000009:adverse effects*; D006801:Humans; D008943:Mitral Valve; D013927:Thrombosis / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000209:etiology; D014463:Ultrasonography
chemical_list: D000925:Anticoagulants