title: MR findings of ovarian tumors with hormonal activity, with emphasis on tumors other than sex cord-stromal tumors.
abstract: Sex cord-stromal tumors including granulosa cell tumor, thecoma, Sertoli stromal cell tumor and steroid cell tumor are noted for their hormonal activity. However, there are many kinds of ovarian tumors other than sex cord-stromal tumors and tumor-like conditions with endocrine manifestations. Cross-sectional imaging, especially MR, can provide precise features of ovarian tumors and uterine morphological change even in a clinically latent excess of estrogen. In this article, we demonstrate typical imaging findings of ovarian tumors with hormonal activity. We also shortly explain the mechanism of the virilization and hyperestrogenism caused by ovarian tumors and tumor-like conditions.
authors.affiliation: Department of Radiology, Graduate School of Comprehensive Human Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan. ytanaka@md.tsukuba.ac.jp
authors.forename: Yumiko Oishi
authors.initials: YO
authors.lastname: Tanaka
authors.forename: Tsukasa Sasaki
authors.initials: TS
authors.lastname: Saida
authors.forename: Rie
authors.initials: R
authors.lastname: Minami
authors.forename: Takako
authors.initials: T
authors.lastname: Yagi
authors.forename: Hajime
authors.initials: H
authors.lastname: Tsunoda
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Yoshikawa
authors.forename: Manabu
authors.initials: M
authors.lastname: Minami
mesh_terms: D000728:Androgens / Q000096:biosynthesis*; D004967:Estrogens / Q000096:biosynthesis*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D009373:Neoplasms, Germ Cell and Embryonal / Q000175:diagnosis* / Q000378:metabolism; D009375:Neoplasms, Glandular and Epithelial / Q000175:diagnosis* / Q000378:metabolism; D010049:Ovarian Diseases / Q000175:diagnosis / Q000378:metabolism; D010051:Ovarian Neoplasms / Q000175:diagnosis* / Q000378:metabolism / Q000473:pathology; D010053:Ovary / Q000473:pathology*; D018312:Sex Cord-Gonadal Stromal Tumors
chemical_list: D000728:Androgens; D004967:Estrogens