Fly MARCM and mouse MADM: genetic methods of labeling and manipulating single neurons.
The Golgi staining method has served neuroscience well for more than a century. In this assay I review recent progresses using genetic methods to recapitulate and extend the Golgi staining method. These methods enable new discoveries on organization and development of neuronal circuits in the fly and mouse brains.
Luo
Liqun
L
Department of Biological Sciences and Howard Hughes Medical Institute, Stanford University, Stanford, CA 94305, USA. lluo@stanford.edu
D000818:Animals; D019070:Cell Lineage; D004175:Diptera; D005819:Genetic Markers / Q000235:genetics; D005821:Genetic Techniques; D051379:Mice; D009030:Mosaicism; D009474:Neurons / Q000502:physiology* / Q000648:ultrastructure*; D009833:Olfactory Pathways / Q000166:cytology / Q000378:metabolism; D016622:Silver Staining
D005819:Genetic Markers