title: Osteolysis after the use of a silicon-stabilized tricalcium phosphate-based bone substitute in a radius fracture: a case report.
abstract: Skelite, a silicon-stabilized tricalcium phosphate-based bone substitute, is a synthetic alternative to the autogenous bone graft. We present a foreign body inflammatory reaction resulting in extensive osteolysis that occurred after use of Skelite as a void filler in the surgical reconstruction of a distal radius fracture.
authors.affiliation: University of Toronto Hand Program and Toronto Western Hospital, University Health Network, Toronto, Canada.
authors.forename: Timothy
authors.initials: T
authors.lastname: Leroux
authors.forename: Bayardo
authors.initials: B
authors.lastname: Perez-Ordonez
authors.forename: Herbert P
authors.initials: HP
authors.lastname: von Schroeder
mesh_terms: D018786:Bone Substitutes / Q000009:adverse effects*; D002130:Calcium Phosphates / Q000009:adverse effects*; D005260:Female; D005593:Fracture Fixation, Internal; D006801:Humans; D008875:Middle Aged; D010014:Osteolysis / Q000139:chemically induced*; D011885:Radius Fractures / Q000601:surgery*; D012825:Silicon / Q000009:adverse effects*
chemical_list: D018786:Bone Substitutes; D002130:Calcium Phosphates; C018392:tricalcium phosphate; D012825:Silicon