title: Oxidants and ocular tumors.
abstract: Serum superoxide dismutase and catalase assays were performed using spectrophotometry in 60 adults and children with benign or malignant tumors and in controls. There was a statistically significant difference in the antioxidative status of children with intraocular tumors (primary retinoblastoma) compared with children without tumors. The difference was not significant in adults. These enzymes may be of value in the early diagnosis of malignant intraocular tumor, especially retinoblastoma.
authors.affiliation: Department of Opthalmology, Institute of Medical Sciences, Banaras Hindu University, India. RJFugomd@fugoblade.com
authors.forename: Rajendra
authors.initials: R
authors.lastname: Singh
authors.forename: Abhijit
authors.initials: A
authors.lastname: Chattopadhyay
authors.forename: Alka
authors.initials: A
authors.lastname: Agarwal
authors.forename: S K
authors.initials: SK
authors.lastname: Bhattacharya
authors.forename: A K
authors.initials: AK
authors.lastname: Bhattacharya
mesh_terms: D000328:Adult; D000367:Age Factors; D002374:Catalase / Q000097:blood; D002648:Child; D005134:Eye Neoplasms / Q000201:enzymology / Q000209:etiology* / Q000378:metabolism; D005260:Female; D006801:Humans; D008297:Male; D016877:Oxidants / Q000378:metabolism*; D018384:Oxidative Stress; D012175:Retinoblastoma / Q000201:enzymology / Q000209:etiology* / Q000378:metabolism; D013482:Superoxide Dismutase / Q000097:blood
chemical_list: D016877:Oxidants; D002374:Catalase; D013482:Superoxide Dismutase