Induction of cell death by photodynamic therapy with water-soluble lipid-membrane-incorporated [60]fullerene.
Intracellular uptake of a lipid-membrane-incorporated C(60) with a cationic surface into HeLa cells was found to induce cell death under visible light irradiation in high efficiency.
Ikeda
Atsushi
A
Graduate School of Materials Science, Nara Institute of Science and Technology, Ikoma, Nara 630-0192, Japan. aikeda@ms.naist.jp
Doi
Yuki
Y
Nishiguchi
Koji
K
Kitamura
Keiko
K
Hashizume
Mineo
M
Kikuchi
Jun-Ichi
J
Yogo
Keiichiro
K
Ogawa
Takuya
T
Takeya
Tatsuo
T
D017209:Apoptosis / Q000187:drug effects; D016923:Cell Death / Q000187:drug effects / Q000528:radiation effects; D005260:Female; D037741:Fullerenes / Q000737:chemistry / Q000493:pharmacokinetics / Q000494:pharmacology*; D006367:HeLa Cells; D006801:Humans; D008027:Light; D008081:Liposomes / Q000138:chemical synthesis / Q000737:chemistry; D008567:Membranes, Artificial; D015394:Molecular Structure; D010778:Photochemotherapy / Q000379:methods*; D012995:Solubility; D013329:Structure-Activity Relationship; D013499:Surface Properties; D002583:Uterine Cervical Neoplasms / Q000188:drug therapy* / Q000378:metabolism; D014867:Water / Q000737:chemistry
D037741:Fullerenes; D008081:Liposomes; D008567:Membranes, Artificial; D014867:Water; C069837:fullerene C60