Tricalysiamides A-D, diterpenoid alkaloids from Tricalysia dubia.
Four rearranged ent-kaurane diterpenoid alkaloids, tricalysiamides A-D (1-4), having a cafestol-type carbon framework were isolated from the wood of Tricalysia dubia. Their absolute structures were determined on the basis of 2D NMR spectroscopy, X-ray crystallographic analysis, and chemical methods.
Nishimura
Koichi
K
School of Pharmacy, Tokyo University of Pharmacy and Life Science, 1432-1 Horinouchi, Hachioji, Tokyo 192-0392, Japan.
Hitotsuyanagi
Yukio
Y
Sugeta
Noriko
N
Fukaya
Haruhiko
H
Aoyagi
Yutaka
Y
Hasuda
Tomoyo
T
Kinoshita
Takeshi
T
Takeya
Koichi
K
D000470:Alkaloids / Q000737:chemistry / Q000302:isolation & purification*; D018360:Crystallography, X-Ray; D045786:Diterpenes, Kaurane / Q000737:chemistry / Q000302:isolation & purification*; D007564:Japan; D008968:Molecular Conformation; D015394:Molecular Structure; D010946:Plants, Medicinal / Q000737:chemistry*; D019666:Rubiaceae / Q000737:chemistry*
D000470:Alkaloids; D045786:Diterpenes, Kaurane