Evaluation of moxalactam with the BD phoenix system for detection of methicillin resistance in coagulase-negative staphylococci.
The performance of moxalactam with the BD Phoenix system for the detection of methicillin resistance in coagulase-negative staphylococci was evaluated by use of a collection of 186 strains. Moxalactam was a better drug as an indicator of methicillin resistance for mecA-positive strains than oxacillin and cefoxitin were. For strains other than Staphylococcus saprophyticus, a moxalactam MIC >16 microg/ml was indicative of methicillin resistance.
Pupin
H
H
CHU de Bordeaux, Hôpital Pellegrin, Laboratoire de Bactériologie, Place Amélie Raba Léon, 33076 Bordeaux, France.
Renaudin
H
H
Join-Lambert
O
O
Bébéar
C
C
Mégraud
F
F
Lehours
P
P
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001426:Bacterial Proteins / Q000235:genetics; D003030:Coagulase / Q000378:metabolism*; D006801:Humans; D016106:Methicillin Resistance / Q000235:genetics; D008826:Microbial Sensitivity Tests / Q000379:methods / Q000592:standards; D009070:Moxalactam / Q000494:pharmacology*; D046915:Penicillin-Binding Proteins; D011933:Reagent Kits, Diagnostic; D013210:Staphylococcus / Q000145:classification / Q000187:drug effects* / Q000201:enzymology / Q000235:genetics
D000900:Anti-Bacterial Agents; D001426:Bacterial Proteins; D003030:Coagulase; D046915:Penicillin-Binding Proteins; D011933:Reagent Kits, Diagnostic; C487789:mecA protein, Staphylococcus aureus; D009070:Moxalactam