title: Fungal endophthalmitis complicating subconjunctival injection of triamcinolone acetonide in anterior scleritis.
abstract: Fungal endophthalmitis following subconjunctival triamcinolone acetonide in anterior scleritis is a rare complication. Two patients with anterior scleritis, who received subconjunctival injection of triamcinolone developed fungal endophthalmitis. Both patients were positive by smear and polymerase chain reaction for 28S ribosomal RNA gene for fungus. Colletotrichum dematium was identified in one patient. Both patients responded well to pars plana vitrectomy and antifungal therapy.
authors.affiliation: Department of Ophthalmology, Postgraduate Institute of Medical Education and Research Postgraduate Institute of Medical Education and Research, Chandigarh, India.
authors.forename: Ramandeep
authors.initials: R
authors.lastname: Singh
authors.forename: Vishali
authors.initials: V
authors.lastname: Gupta
authors.forename: Arunaloke
authors.initials: A
authors.lastname: Chakarborty
authors.forename: Raje
authors.initials: R
authors.lastname: Nijhawan
authors.forename: Sunil
authors.initials: S
authors.lastname: Arora
authors.forename: Amod
authors.initials: A
authors.lastname: Gupta
mesh_terms: D000328:Adult; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage* / Q000009:adverse effects* / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use; D020231:Colletotrichum / Q000302:isolation & purification; D003228:Conjunctiva; D009877:Endophthalmitis / Q000175:diagnosis / Q000382:microbiology* / Q000601:surgery; D006801:Humans; D007267:Injections; D008297:Male; D033401:Microscopy, Acoustic; D008875:Middle Aged; D009181:Mycoses / Q000139:chemically induced* / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology; D012339:RNA, Ribosomal, 28S / Q000032:analysis; D015423:Scleritis / Q000188:drug therapy*; D014222:Triamcinolone Acetonide / Q000008:administration & dosage* / Q000009:adverse effects* / Q000627:therapeutic use; D014821:Vitrectomy
chemical_list: D000893:Anti-Inflammatory Agents; D000935:Antifungal Agents; D012339:RNA, Ribosomal, 28S; D014222:Triamcinolone Acetonide