title: Haemodynamic significance of an anomalous right coronary with inter-arterial course assessed with intracoronary pressure measurements during dobutamine challenge.
abstract: Autopsy studies have associated congenital coronary anomalies with the risk of sudden cardiac death. However, not all patients with anomalous coronary arteries die suddenly. A means of assessing the potential for ischaemia and thus predicting the risk of sudden death in these patients may be necessary for directing treatment. We present the case of a patient with an anomalous right coronary artery originating from the aortic wall above the left sinus of Valsalva, with an anterior inter-arterial course. The haemodynamic significance of this anomaly was assessed using intracoronary pressure-wire measurements at rest and during dobutamine stress. This technique could be a valid means for assessing stress-induced ischaemia and, therefore, by inference, the risk of sudden cardiac death in these patients.
authors.forename: Konstantinos
authors.initials: K
authors.lastname: Dimopoulos
authors.forename: Carlo
authors.initials: C
authors.lastname: Di Mario
authors.forename: Peter
authors.initials: P
authors.lastname: Barlis
authors.forename: Dudley
authors.initials: D
authors.lastname: Pennell
authors.forename: Omer
authors.initials: O
authors.lastname: Goktekin
authors.forename: Sam
authors.initials: S
authors.lastname: Kaddoura
authors.forename: Michael A
authors.initials: MA
authors.lastname: Gatzoulis
mesh_terms: D002408:Catheters, Indwelling; D017023:Coronary Angiography / Q000379:methods; D003330:Coronary Vessel Anomalies / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000503:physiopathology; D003331:Coronary Vessels / Q000187:drug effects / Q000502:physiology; D004280:Dobutamine / Q000494:pharmacology; D005260:Female; D006439:Hemodynamics / Q000187:drug effects / Q000502:physiology*; D006801:Humans; D008875:Middle Aged
chemical_list: D004280:Dobutamine