title: Early unreamed intramedullary nailing of femoral fractures is safe in patients with severe thoracic trauma.
abstract: BACKGROUND
  The timing of fixation of femoral fractures in multiply injured patients with severe thoracic trauma is discussed controversially. Some authors recommend damage control surgery, whereas other authors prefer early definitive treatment. The aim of our study was to investigate the effect of early definitive fixation of femoral fractures on outcomes in multiply injured patients with severe thoracic trauma.
  
  
  METHODS
  Between May 1, 1998 and December 31, 2004, 578 severely injured patients were admitted to our institution. Forty-five patients met the inclusion criteria for the study cohort (severe thoracic trauma and femoral fracture stabilized with unreamed intramedullary nailing [IMN] within the first 24 hours) and 107 patients were selected for the control cohort (severe thoracic trauma without any lower extremity fracture). Inclusion criteria for both cohorts were age 15 to 55 years with blunt trauma (e.g. motor vehicle collisions, falls) including severe thoracic trauma (Abbreviated Injury Scale [AIS] score >or=3) and Injury Severity Score (ISS) >or=18. For comparison between the cohorts data on patients status (Glasgow Coma Scale score at arrival, Revised Trauma Score, Trauma and Injury Severity Score survival prognosis, Simplified Acute Physiology Score II score), treatment (intubation rate, thoracic drainage, surgery), and outcomes (duration of intensive care unit stay and ventilation, rate of adult respiratory distress syndrome [ARDS], multiple organ failure syndrome [MOFS], and mortality) were selected from hospital databases. Dichotomous data were analyzed by chi test; continuous data were analyzed by Student's t test. Any values of p < 0.05 were considered significant for any test.
  
  
  RESULTS
  Both cohorts were comparable with regard to demographic data, ISS, AIS score in the thoracic region, and incidence and severity of brain injury. There was no difference in dependent parameters in both cohorts. Rates of ARDS, MOFS, and mortality were not negatively influenced by early unreamed IMN.
  
  
  CONCLUSIONS
  Early unreamed IMN of femoral fractures in multiply injured patients with severe thoracic trauma is a safe procedure and seems to be justified to achieve early definitive care.
authors.affiliation: Department of Trauma Surgery, Trauma Hospital Lorenz Boehler, Austria. weninger@auva.at
authors.forename: Patrick
authors.initials: P
authors.lastname: Weninger
authors.forename: Markus
authors.initials: M
authors.lastname: Figl
authors.forename: Ralf
authors.initials: R
authors.lastname: Spitaler
authors.forename: Walter
authors.initials: W
authors.lastname: Mauritz
authors.forename: Harald
authors.initials: H
authors.lastname: Hertz
mesh_terms: D015998:Abbreviated Injury Scale; D000293:Adolescent; D000328:Adult; D005260:Female; D005264:Femoral Fractures / Q000150:complications / Q000601:surgery*; D005594:Fracture Fixation, Intramedullary; D006801:Humans; D015601:Injury Severity Score; D008297:Male; D008875:Middle Aged; D009104:Multiple Trauma / Q000150:complications; D011379:Prognosis; D013898:Thoracic Injuries / Q000150:complications* / Q000473:pathology; D014949:Wounds, Nonpenetrating