title: Novel aminoethylbiphenyls as 5-HT7 receptor ligands.
abstract: The synthesis of a series of aminoethylbiphenyls as novel 5-HT(7) receptor ligands is described. The novel derivatives exhibit high affinity for the 5-HT(7) receptor with selectivity toward 5-HT(1A) receptor.
authors.affiliation: Centre d'Etudes et de Recherche sur le Médicament de Normandie EA3915, Université de Caen, UFR des Sciences Pharmaceutiques, 5, rue Vaubénard 14032 Caen Cedex, France.
authors.forename: Magalie
authors.initials: M
authors.lastname: Paillet-Loilier
authors.forename: Frédéric
authors.initials: F
authors.lastname: Fabis
authors.forename: Alban
authors.initials: A
authors.lastname: Lepailleur
authors.forename: Ronan
authors.initials: R
authors.lastname: Bureau
authors.forename: Sabrina
authors.initials: S
authors.lastname: Butt-Gueulle
authors.forename: François
authors.initials: F
authors.lastname: Dauphin
authors.forename: Aurélien
authors.initials: A
authors.lastname: Lesnard
authors.forename: Catherine
authors.initials: C
authors.lastname: Delarue
authors.forename: Hubert
authors.initials: H
authors.lastname: Vaudry
authors.forename: Sylvain
authors.initials: S
authors.lastname: Rault
mesh_terms: D000611:Aminobiphenyl Compounds / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D000818:Animals; D006801:Humans; D008024:Ligands; D051381:Rats; D011985:Receptors, Serotonin / Q000737:chemistry* / Q000187:drug effects
chemical_list: D000611:Aminobiphenyl Compounds; D008024:Ligands; D011985:Receptors, Serotonin; C104425:serotonin 7 receptor