title: Adaptive effects of dexamethasone in stress exposure.
abstract: Disorders in the compensatory adaptive processes underlie the development of many somatic diseases. The neuroimmunoendocrine complex and one of its main components, the hypothalamic-pituitary-adrenal system, play the leading role in the maintenance of the adaptation reserve. Treatment with a synthetic analog of hydrocortisone (final effector of this system) in low doses modulates its function by inducing positive changes in the adaptive mechanisms under conditions of stress exposure.
authors.affiliation: Institute of Pharmacology, Tomsk Research Center, Siberian Division of Russian Academy of medical Sciences. evbor@hotbox.ru
authors.forename: V V
authors.initials: VV
authors.lastname: Udut
authors.forename: G A
authors.initials: GA
authors.lastname: Popova
authors.forename: E V
authors.initials: EV
authors.lastname: Borodulina
mesh_terms: D000222:Adaptation, Physiological; D000324:Adrenocorticotropic Hormone / Q000097:blood; D000328:Adult; D002940:Circadian Rhythm; D003907:Dexamethasone / Q000494:pharmacology*; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D007328:Insulin / Q000097:blood; D008297:Male; D013312:Stress, Physiological / Q000097:blood*
chemical_list: D007328:Insulin; D003907:Dexamethasone; D000324:Adrenocorticotropic Hormone; D006854:Hydrocortisone