title: Cardiac angiosarcoma: report of a case diagnosed by echocardiographic-guided fine-needle aspiration.
abstract: The authors present a case of cardiac angiosarcoma diagnosed by fine-needle aspiration (FNA) in a 33-year-old male. A percutaneous right atrial mass biopsy was performed via a right internal jugular venous approach and under echocardiographic guidance. FNA showed pleomorphic spindle-shaped cells present singly and in small clusters in a background of hemorrhage. Occasional pseudo-acini or microacinar structures were observed, that are lined with abnormal spindly to polygonal cells, indicative of vasoformative structures. Immunostain for CD31 was strongly positive. A diagnosis of cardiac angiosarcoma was made, following which, the patient underwent treatment with chemotherapy.
authors.affiliation: Department of Pathology and Laboratory Medicine, Emory University, School of Medicine, Atlanta, GA, USA.
authors.forename: Ritu
authors.initials: R
authors.lastname: Bhalla
authors.forename: Aziza
authors.initials: A
authors.lastname: Nassar
mesh_terms: D000328:Adult; D044963:Biopsy, Fine-Needle; D004452:Echocardiography; D006338:Heart Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology*; D006394:Hemangiosarcoma / Q000000981:diagnostic imaging* / Q000473:pathology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male