title: Building blocks.
abstract: This contribution illustrates the versatility of fundamental approaches in industrial biotransformations. The applicability of biotechnology in organic synthesis on an industrial scale is discussed, followed by an overview of historical development and future progress. This chapter depicts three different approaches for the use of biocatalysts in production processes: non-chiral synthesis, asymmetric synthesis, and racemic and dynamic resolution. Applications for whole cells and isolated enzymes as catalysts are introduced. Finally, critical but optimistic conclusions are given.
authors.affiliation: Institute for Technical Biocatalysis, Hamburg University of Technology, Denickestr. 15, 21073 Hamburg, Germany.
authors.forename: Lutz
authors.initials: L
authors.lastname: Hilterhaus
authors.forename: Andreas
authors.initials: A
authors.lastname: Liese
mesh_terms: D001709:Biotechnology / Q000379:methods*; D001711:Biotransformation; D002384:Catalysis; D002617:Chemical Industry / Q000379:methods; D015394:Molecular Structure; D009930:Organic Chemicals / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D009930:Organic Chemicals