title: Efficacy of Tonimer gel spray on postoperative nasal care after endonasal surgery.
abstract: OBJECTIVE
  To investigate the effect of the addition of Tonimer gel spray into nasal mucosa care on nasal mucosal findings and patient comfort in the postoperative period of endonasal surgery.
  
  
  METHODS
  40 patients who underwent endonasal surgery were included in the study. For the postoperative nasal care, isotonic saline was applied to both nasal cavities, and subsequently, Tonimer nasal gel spray was additionally applied to the right nasal cavity. Patients were examined on the 2nd, 7th, and 15th postoperative days. The findings of the examinations were scored with respect to crusting and the patient nasal comfort was assessed using the visual analog scale (VAS).
  
  
  RESULTS
  The VAS values which measure patient comfort and crusting were significantly lower on the Tonimer side compared to control (p < 0.01).
  
  
  CONCLUSIONS
  Tonimer and saline combination was found to be superior to saline per se in decreasing crusting and improving patient nasal comfort in the postoperative period.
authors.affiliation: Department of Otorhinolaryngology - Head and Neck Surgery, Sisli Etfal Research and Education Hospital, Istanbul, Turkey. i_ercan@yahoo.com
authors.forename: Ibrahim
authors.initials: I
authors.lastname: Ercan
authors.forename: Burak Omur
authors.initials: BO
authors.lastname: Cakir
authors.forename: Muge
authors.initials: M
authors.lastname: Ozcelik
authors.forename: Suat
authors.initials: S
authors.lastname: Turgut
mesh_terms: D000281:Administration, Intranasal; D000328:Adult; D004724:Endoscopy / Q000379:methods*; D005260:Female; D005782:Gels; D006801:Humans; D006820:Hyaluronic Acid / Q000627:therapeutic use; D007552:Isotonic Solutions / Q000627:therapeutic use*; D008297:Male; D009079:Mucociliary Clearance / Q000187:drug effects; D009297:Nasal Mucosa / Q000187:drug effects; D009298:Nasal Polyps / Q000601:surgery*; D009330:Nebulizers and Vaporizers; D013517:Otorhinolaryngologic Surgical Procedures / Q000379:methods*; D010149:Postoperative Pain / Q000188:drug therapy*; D010205:Pantothenic Acid / Q000031:analogs & derivatives / Q000627:therapeutic use; D011182:Postoperative Care; D012221:Rhinitis, Allergic, Perennial / Q000601:surgery*; D014020:Tissue Extracts / Q000627:therapeutic use
chemical_list: D005782:Gels; D007552:Isotonic Solutions; D014020:Tissue Extracts; D010205:Pantothenic Acid; C007288:dexpanthenol; D006820:Hyaluronic Acid