title: Eccrine porocarcinoma: a case with an obscure primary tumor diagnosed from lymph node metastasis.
abstract: Eccrine porocarcinoma (EPC), a rare malignant epidermal appendage tumor, is mainly seen in elderly patients. A long history is one of its main characteristics. Two types of EPC are known: juxtaepidermal and dermal. The juxtaepidermal type usually has a more aggressive behavior. Lymph node metastasis and high mitotic activity are associated with poor prognosis. A case of EPC with a long-standing but indolent primary site diagnosed from lymph node metastasis is presented here. There was also accompanying chronic dermatitis as a paraneoplastic syndrome. Diagnosing EPC prior to the regional lymph node involvement is the most valuable factor for a successful treatment. Persistent examinations and attempts to find the primary site(s) have to be made in such cases.
authors.affiliation: Department of Pathology, Gülhane Military Medical Academy and Medical Faculty. ogunhan@gata.edu.tr
authors.forename: Omer
authors.initials: O
authors.lastname: Günhan
authors.forename: Yildirim
authors.initials: Y
authors.lastname: Karslioğlu
authors.forename: Melih
authors.initials: M
authors.lastname: Alömeroğlu
authors.forename: Uğur
authors.initials: U
authors.lastname: Berberoğlu
mesh_terms: D018280:Carcinoma, Skin Appendage / Q000150:complications / Q000175:diagnosis / Q000276:immunology / Q000473:pathology*; D049109:Cell Proliferation; D002908:Chronic Disease; D003872:Dermatitis / Q000209:etiology* / Q000473:pathology; D004439:Eccrine Glands / Q000276:immunology / Q000473:pathology*; D005260:Female; D006801:Humans; D019394:Ki-67 Antigen / Q000032:analysis; D008198:Lymph Nodes / Q000473:pathology*; D008207:Lymphatic Metastasis; D008875:Middle Aged; D010257:Paraneoplastic Syndromes / Q000209:etiology* / Q000473:pathology; D011379:Prognosis; D013544:Sweat Gland Neoplasms / Q000150:complications / Q000175:diagnosis / Q000276:immunology / Q000473:pathology*
chemical_list: D019394:Ki-67 Antigen