title: Aspergillus endocarditis of the mitral valve in a lung-transplant patient.
abstract: A 57-year-old man underwent bilateral lung transplantation at our hospital. On histopathology, aspergillomas were identified in the upper lobes of the explanted lungs. After being treated and discharged from the hospital, he returned 4 months later with ischemic chest pain, which was due to a myocardial infarction complicated by cardiogenic shock. He also had a large vegetation on the anterior mitral leaflet. Herein, we describe the patient's symptoms, complications, treatment, and recovery. To the best of our knowledge, ours is only the 2nd report of a patient who developed Aspergillus endocarditis after lung transplantation and the 1st such patient to have undergone successful mitral valve replacement.
authors.affiliation: Department of Cardiac Surgery, The Prince Charles Hospital, Chermside, Queensland 4032, Australia. drpankajsaxena@hotmail.com
authors.forename: Pankaj
authors.initials: P
authors.lastname: Saxena
authors.forename: Belinda
authors.initials: B
authors.lastname: Clarke
authors.forename: John
authors.initials: J
authors.lastname: Dunning
mesh_terms: D015906:Angioplasty, Balloon, Coronary; D000935:Antifungal Agents / Q000627:therapeutic use; D001228:Aspergillosis / Q000150:complications* / Q000188:drug therapy / Q000382:microbiology; D001232:Aspergillus fumigatus; D023921:Coronary Stenosis / Q000150:complications / Q000628:therapy; D004696:Endocarditis / Q000188:drug therapy / Q000209:etiology* / Q000382:microbiology; D019918:Heart Valve Prosthesis Implantation; D006801:Humans; D008172:Lung Diseases, Fungal / Q000150:complications* / Q000188:drug therapy / Q000382:microbiology; D016040:Lung Transplantation / Q000009:adverse effects; D008297:Male; D008875:Middle Aged; D008944:Mitral Valve Insufficiency / Q000209:etiology* / Q000382:microbiology / Q000628:therapy; D009203:Myocardial Infarction / Q000209:etiology; D012770:Shock, Cardiogenic / Q000209:etiology
chemical_list: D000935:Antifungal Agents