Cutaneous epithelioid angioleiomyoma with clear-cell change.
Epithelioid angioleiomyoma is rare in the skin and subcutis. We report here an unusual case of epithelioid angioleiomyoma with prominent clear-cell change. Smooth-muscle differentiation was confirmed by immunostains. The extensive clear-cell change in epithelial cells and the marked hyalinization and calcification made the histologic differential diagnosis challenging. Epithelioid angioleiomyoma shares some histologic characteristics with glomus tumors and seems to be an intermediate entity between angioleiomyomas and glomus tumors.
Liu
Jian Ying
JY
Department of Pathology, Health Science Center of Peking University, Beijing, China. liujianying@hsc.pku.edu.cn
Liao
Song Lin
SL
Zheng
Jie
J
D000199:Actins / Q000032:analysis; D000328:Adult; D018229:Angiomyoma / Q000737:chemistry / Q000175:diagnosis* / Q000473:pathology; D002114:Calcinosis / Q000175:diagnosis; D002454:Cell Differentiation; D003893:Desmin / Q000032:analysis; D003937:Diagnosis, Differential; D004817:Epidermis / Q000737:chemistry / Q000473:pathology*; D015622:Epithelioid Cells / Q000737:chemistry / Q000473:pathology*; D005260:Female; D005918:Glomus Tumor / Q000737:chemistry / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D006818:Hyalin / Q000378:metabolism; D007150:Immunohistochemistry; D032389:Myocytes, Smooth Muscle / Q000473:pathology; D012155:Reticulin / Q000032:analysis; D009418:S100 Proteins / Q000032:analysis; D012878:Skin Neoplasms / Q000737:chemistry / Q000175:diagnosis* / Q000473:pathology; D014617:Vacuoles / Q000473:pathology
D000199:Actins; D003893:Desmin; D012155:Reticulin; D009418:S100 Proteins