Membrane trafficking: three steps to fusion.
Membrane fusion involves the action of members of the SNARE protein family as well as Sec1/Munc18 (SM) proteins, which have been found to interact with SNAREs in three distinct ways. Recent work has established that Munc18-1 directly stimulates fusion and possibly uses all three modes of SNARE interaction.
Burgoyne
Robert D
RD
The Physiological Laboratory, School of Biomedical Sciences, University of Liverpool, Crown Street, Liverpool, UK. burgoyne@liverpool.ac.uk
Morgan
Alan
A
D000818:Animals; D008561:Membrane Fusion; D008566:Membranes / Q000378:metabolism*; D008958:Models, Molecular; D051938:Munc18 Proteins / Q000378:metabolism*; D050600:SNARE Proteins / Q000378:metabolism*; D015003:Yeasts / Q000378:metabolism
D051938:Munc18 Proteins; D050600:SNARE Proteins