Effect of hypobaric hypoxia on the development of long-term posttetanic potentiation in slices of rat olfactory cortex: correction with hypoxic preconditioning.
We studied the effect of in vivo hypobaric hypoxia on the development (after 3 h) of in vitro long-term posttetanic potentiation in Wistar rats. Severe hypoxia suppressed induction of posttetanic potentiation in slices of the olfactory cortex. Preconditioning exposure (moderate hypobaric hypoxia) prevented inhibition of posttetanic potentiation induced by severe hypoxia.
Lyubimov
Ya E
YE
I. P. Pavlov Institute of Physiology, Russian Academy of Sciences, St. Petersburg.
Tyulkova
E I
EI
Samoilov
M O
MO
D000818:Animals; D000860:Hypoxia; D019194:Ischemic Preconditioning; D017774:Long-Term Potentiation / Q000502:physiology*; D008297:Male; D009833:Olfactory Pathways / Q000503:physiopathology*; D051381:Rats; D017208:Rats, Wistar; D013746:Tetany / Q000503:physiopathology*