title: A reconstruction algorithm for breast cancer imaging with electrical impedance tomography in mammography geometry.
abstract: The conductivity and permittivity of breast tumors are known to differ significantly from those of normal breast tissues, and electrical impedance tomography (EIT) is being studied as a modality for breast cancer imaging to exploit these differences. At present, X-ray mammography is the primary standard imaging modality used for breast cancer screening in clinical practice, so it is desirable to study EIT in the geometry of mammography. This paper presents a forward model of a simplified mammography geometry and a reconstruction algorithm for breast tumor imaging using EIT techniques. The mammography geometry is modeled as a rectangular box with electrode arrays on the top and bottom planes. A forward model for the electrical impedance imaging problem is derived for a homogeneous conductivity distribution and is validated by experiment using a phantom tank. A reconstruction algorithm for breast tumor imaging based on a linearization approach and the proposed forward model is presented. It is found that the proposed reconstruction algorithm performs well in the phantom experiment, and that the locations of a 5-mm-cube metal target and a 6-mm-cube agar target could be recovered at a target depth of 15 mm using a 32 electrode system.
authors.affiliation: Department of Electrical and Electronics Engineering, Kangwon National University, 192-1, Hyoza 2 dong, Chunchon, Kangwondo, Korea. mhchoi@kangwon.ac.kr
authors.forename: Myoung Hwan
authors.initials: MH
authors.lastname: Choi
authors.forename: Tzu-Jen
authors.initials: TJ
authors.lastname: Kao
authors.forename: David
authors.initials: D
authors.lastname: Isaacson
authors.forename: Gary J
authors.initials: GJ
authors.lastname: Saulnier
authors.forename: Jonathan C
authors.initials: JC
authors.lastname: Newell
mesh_terms: D000465:Algorithms; D001943:Breast Neoplasms / Q000175:diagnosis* / Q000503:physiopathology*; D003952:Diagnostic Imaging / Q000379:methods*; D017097:Electric Impedance; D006801:Humans; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D008327:Mammography / Q000379:methods; D010992:Plethysmography, Impedance / Q000379:methods*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D014054:Tomography / Q000379:methods