title: Efficient quantification of the left ventricular volume using 3-dimensional echocardiography: the minimal number of equiangular long-axis images for accurate quantification of the left ventricular volume.
abstract: For quantification of the left ventricular volume from 3-dimensional echocardiograms a number of cross-sectional images are used. The goal of this study was to determine the minimum number of long-axis images necessary for accurate quantification of the left ventricular volume. A strong correlation was observed between volumes obtained from magnetic resonance imaging and 3-dimensional echocardiography using 16 equiangular images (r = 0.99; y = 0.95x + 3.3 mL; standard error of the estimate = 7.0 mL; N = 30). Comparison of these results with random subsets showed a significant difference for volumes obtained with 4 and 2 equiangular images (P < .005). However, when the subsets were selected to target the eccentric region of the endocardial border this was only the case for subsets of two images (P < .001). This study demonstrates that accurate left ventricular volume quantification can be performed with as little as 8 equiangular long-axis images. By selecting the correctly oriented image set, this number can even be brought down to 4, which will further reduce the analysis time.
authors.affiliation: Interuniversity Cardiology Institute of the Netherlands, Utrecht, The Netherlands. m.voormolen@erasmusmc.nl <m.voormolen@erasmusmc.nl>
authors.forename: Marco M
authors.initials: MM
authors.lastname: Voormolen
authors.forename: Boudewijn J
authors.initials: BJ
authors.lastname: Krenning
authors.forename: Robert-Jan
authors.initials: RJ
authors.lastname: van Geuns
authors.forename: Jerome
authors.initials: J
authors.lastname: Borsboom
authors.forename: Charles T
authors.initials: CT
authors.lastname: Lancée
authors.forename: Folkert J
authors.initials: FJ
authors.lastname: ten Cate
authors.forename: Jos R T C
authors.initials: JR
authors.lastname: Roelandt
authors.forename: Anton F W
authors.initials: AF
authors.lastname: van der Steen
authors.forename: Nico
authors.initials: N
authors.lastname: de Jong
mesh_terms: D000328:Adult; D000368:Aged; D002306:Cardiac Volume; D002311:Cardiomyopathy, Dilated / Q000000981:diagnostic imaging / Q000473:pathology / Q000503:physiopathology; D019560:Echocardiography, Three-Dimensional / Q000379:methods*; D006339:Heart Rate / Q000502:physiology; D006352:Heart Ventricles / Q000000981:diagnostic imaging* / Q000473:pathology / Q000503:physiopathology; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000000981:diagnostic imaging / Q000473:pathology / Q000503:physiopathology; D011379:Prognosis; D015203:Reproducibility of Results; D012720:Severity of Illness Index; D016277:Ventricular Function, Left / Q000502:physiology*