Oxidative stress detection: what for? Part II.
Oxygen-free radicals, more generally known as reactive oxygen species (ROS) along with nitrogen species (RNS) are well recognised for playing a dual role both deleterious and beneficial species. The cumulative generation of ROS/RNS through either endogenous or exogenous insults is termed oxidative stress and is common for many types of diseases that are linked with altered redox regulation of cellular signalling pathways.
Palmieri
B
B
Department of General Surgery and Surgical Specialties, University of Modena and Reggio Emilia Medical School, Surgical Clinic, Modena, Italy. palmieri@unimo.it
Sblendorio
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V
D000818:Animals; D000975:Antioxidants / Q000494:pharmacology / Q000627:therapeutic use*; D006801:Humans; D010084:Oxidation-Reduction / Q000187:drug effects; D018384:Oxidative Stress / Q000187:drug effects* / Q000502:physiology; D026361:Reactive Nitrogen Species / Q000037:antagonists & inhibitors / Q000378:metabolism; D017382:Reactive Oxygen Species / Q000037:antagonists & inhibitors / Q000378:metabolism; D015398:Signal Transduction / Q000187:drug effects / Q000502:physiology
D000975:Antioxidants; D026361:Reactive Nitrogen Species; D017382:Reactive Oxygen Species