Current role of cardiac computed tomography.
The introduction of recent generations of multidetector computed tomography scanners has brought about substantial improvements in spatial and especially temporal resolution which have made imaging of the heart and, under certain conditions, visualization of the coronary arteries possible. Non-enhanced scans allow visualization of cardiac and coronary artery calcification. After intravenous injection of contrast agent, it is possible to visualize cardiac chambers and to analyze the coronary artery lumen. Morphological imaging of the heart, for example in the context of congenital heart disease, is possible by computed tomography (CT) and can, in some very selected cases, be clinically useful as an adjunct to echocardiography or magnetic resonance imaging. Functional imaging allows to analyze left and right ventricular function by CT.CT plays a more prominent clinical role in the context of coronary artery visualization. Coronary calcifications are indicative of coronary atherosclerosis and the presence and amount of coronary artery calcium have a strong predictive value concerning future cardiovascular events, even in asymptomatic individuals. It can potentially be used for refined risk stratification. Contrast-enhanced "CT coronary angiography" has become quite reliable under certain conditions (e.g., a low heart rate). The negative predictive value to rule out coronary artery stenoses has been found to be high in several studies. Therefore, clinical utility to rule out significant coronary artery stenoses in patients who are symptomatic, but have a low to intermediate pretest likelihood of disease is assumed. Ideally, "negative" coronary angiograms would be avoided by using coronary CT angiography. Large-scale trials that would pinpoint specific patient groups to benefit from "CT coronary angiography" are currently lacking.
Achenbach
Stephan
S
Department of Medicine 2, University Hospital Erlangen, Germany. stephan.achenbach@med2.med.uni-erlangen.de
Daniel
Werner G
WG
D009202:Cardiomyopathies / Q000000981:diagnostic imaging*; D006331:Heart Diseases / Q000000981:diagnostic imaging*; D006801:Humans; D017410:Practice Guidelines as Topic; D010818:Practice Patterns, Physicians'; D011856:Radiographic Image Enhancement / Q000295:instrumentation / Q000379:methods* / Q000639:trends*; D014057:Tomography, X-Ray Computed / Q000295:instrumentation / Q000379:methods* / Q000639:trends*