title: UV-light induced radiation recall dermatitis after a chemoradiotherapy organ preservation protocol.
abstract: This case report documents a UV-light-induced recall phenomenon and reviews the medical literature. In this patient, we observed a severe recall phenomenon precipitated by an extensive sunlight exposure after a chemoradiotherapy organ preservation protocol. Radiation recall phenomenon is a rare but well-described phenomenon, without clear radiation or drug-specific characteristics. In the medical literature, radiation recall following UV-sunlight exposure seems to be an exceptional event. The etiology remains unknown but could involve local hypersensitivity through a non-immune activation of inflammatory pathways. Due to the increasing number of patients with head and neck malignancies managed with induction chemotherapy and/or chemoradiation organ preservation protocols, the otorhinolaryngologist--head and neck surgeons as well as the radiation therapist should become aware and familiar with this phenomenon.
authors.affiliation: Department of Radiation Oncology, Université Paris V-René Descartes, Hôpital Européen Georges Pompidou, AP-HP, Paris, France.
authors.forename: Romuald
authors.initials: R
authors.lastname: Le Scodan
authors.forename: Benjamin
authors.initials: B
authors.lastname: Wyplosz
authors.forename: Sophie
authors.initials: S
authors.lastname: Couchon
authors.forename: Martin
authors.initials: M
authors.lastname: Housset
authors.forename: Ollivier
authors.initials: O
authors.lastname: Laccourreye
mesh_terms: D000970:Antineoplastic Agents / Q000494:pharmacology*; D003872:Dermatitis / Q000209:etiology*; D006258:Head and Neck Neoplasms / Q000188:drug therapy / Q000532:radiotherapy; D006801:Humans; D007249:Inflammation; D008297:Male; D008875:Middle Aged; D019188:Organ Preservation Solutions / Q000627:therapeutic use*; D011838:Radiation-Sensitizing Agents / Q000009:adverse effects; D011855:Radiodermatitis / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D013472:Sunlight; D013997:Time Factors; D014466:Ultraviolet Rays
chemical_list: D000970:Antineoplastic Agents; D019188:Organ Preservation Solutions; D011838:Radiation-Sensitizing Agents