title: Nasofacial phycomycosis: persistence pays.
abstract: Nasofacial phycomycosis caused by Conidiobolus is a rare fungal infection most often encountered in the developing world in conditions of poverty. A clinical presentation of the natural history of this condition observed over a period of 6 years by a visiting volunteer surgical team demonstrates the role of multimodality surgical and antifungal drug treatment in producing a successful outcome. The particular sensitivity of this infection to the new generation antifungal Voriconazole is noted.
authors.affiliation: Royal Australasian College of Surgeons Specialist Surgical Project, East Timor. mhmoore@internode.net.au
authors.forename: Mark Harold
authors.initials: MH
authors.lastname: Moore
authors.forename: Dan
authors.initials: D
authors.lastname: Murphy
authors.forename: Craig
authors.initials: C
authors.lastname: James
mesh_terms: D000328:Adult; D000935:Antifungal Agents / Q000494:pharmacology / Q000627:therapeutic use*; D020092:Conidiobolus / Q000187:drug effects* / Q000302:isolation & purification; D025141:Drug Resistance, Fungal; D005148:Facial Dermatoses / Q000188:drug therapy* / Q000601:surgery; D005260:Female; D006801:Humans; D017964:Itraconazole / Q000494:pharmacology / Q000627:therapeutic use; D011743:Pyrimidines / Q000494:pharmacology / Q000627:therapeutic use*; D049648:Timor-Leste; D014230:Triazoles / Q000494:pharmacology / Q000627:therapeutic use*; D065819:Voriconazole; D020096:Zygomycosis / Q000188:drug therapy* / Q000601:surgery
chemical_list: D000935:Antifungal Agents; D011743:Pyrimidines; D014230:Triazoles; D017964:Itraconazole; D065819:Voriconazole