title: The role of intragenomic recombination rate in the evolution of population's genetic pool.
abstract: In a simple computer model of population evolution, we have shown that frequency of recombination between haplotypes during the gamete production influences the effectiveness of the reproduction strategy. High recombination rates keeps the fraction of defective alleles low while low recombination rate or uneven distributed recombination spots change the strategy of genomes' evolution and result in the accumulation of heterozygous loci in the genomes. Even short fragment of chromosome with restricted recombination influences the genetic structure of neighboring regions.
authors.affiliation: Department of Genomics, Wrocław University, ul. Przybyszewskiego 63/77, 51-148 Wrocław, Poland.
authors.forename: Marta
authors.initials: M
authors.lastname: Zawierta
authors.forename: Przemysław
authors.initials: P
authors.lastname: Biecek
authors.forename: Wojciech
authors.initials: W
authors.lastname: Waga
authors.forename: Stanisław
authors.initials: S
authors.lastname: Cebrat
mesh_terms: D005075:Biological Evolution; D003198:Computer Simulation; D005260:Female; D014644:Genetic Variation; D005828:Genetics, Population / Q000379:methods*; D006239:Haplotypes; D006801:Humans; D008297:Male; D008957:Models, Genetic; D009010:Monte Carlo Method; D011995:Recombination, Genetic