title: Adjuvant therapy with sorafenib in bone metastases bilateral renal carcinoma: a case report.
abstract: A 69-yr-old man with bilateral and metastatic renal cell carcinoma developed progressive disease after interleukin-2 and interferon therapy. He was submitted to radical left nephrectomy, right nephron-sparing surgery, and bone metastasis removal, followed by therapy with sorafenib. At 12-mo follow-up there was a significant improvement in patient performance status and no evidence of clinical progression.
authors.affiliation: Department of Urology, University of Rome, Italy. sciarrajr@hotmail.com
authors.forename: Alessandro
authors.initials: A
authors.lastname: Sciarra
authors.forename: Ana Maria
authors.initials: AM
authors.lastname: Autran Gomez
authors.forename: Alessandro
authors.initials: A
authors.lastname: Gentilucci
authors.forename: Ulderico
authors.initials: U
authors.lastname: Parente
authors.forename: Stefano
authors.initials: S
authors.lastname: Salciccia
authors.forename: Vincenzo
authors.initials: V
authors.lastname: Gentile
authors.forename: Franco
authors.initials: F
authors.lastname: Di Silverio
mesh_terms: D000368:Aged; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D001557:Benzenesulfonates / Q000627:therapeutic use*; D001859:Bone Neoplasms / Q000188:drug therapy* / Q000556:secondary* / Q000601:surgery; D002292:Carcinoma, Renal Cell / Q000188:drug therapy* / Q000556:secondary* / Q000601:surgery; D003131:Combined Modality Therapy; D006801:Humans; D007680:Kidney Neoplasms / Q000473:pathology* / Q000601:surgery; D008297:Male; D009536:Niacinamide / Q000031:analogs & derivatives; D010671:Phenylurea Compounds; D011725:Pyridines / Q000627:therapeutic use*; D000077157:Sorafenib
chemical_list: D000970:Antineoplastic Agents; D001557:Benzenesulfonates; D010671:Phenylurea Compounds; D011725:Pyridines; D009536:Niacinamide; D000077157:Sorafenib