Molecular networks of brain and immunity.
Exciting complexity of natural phenomena can be based on rather simple biophysical principles. For example, the genetic code is based on a double-helix of DNA formed by planar geometry of weak hydrogen bounds. On the examples of cytokine networks, immune synapse, psychoneuroimmunology and systems biology, this review paper attempts to show how molecular networks both in brain and immunity can be studied using common principles of protein-protein interactions.
Goncharova
Larisa B
LB
Institute Pasteur of St. Petersburg, ul. Mira 14, St. Petersburg 197101, Russia.
Tarakanov
Alexander O
AO
D000818:Animals; D001921:Brain / Q000276:immunology*; D006801:Humans; D007109:Immunity / Q000235:genetics*; D008959:Models, Neurological; D009415:Nerve Net / Q000276:immunology / Q000378:metabolism; D015213:Neuroimmunomodulation / Q000502:physiology; D049490:Systems Biology / Q000379:methods