title: [Histopathological features of joint destruction in rheumatoid arthritis (RA)].
abstract: Recent technologies proceed the remarkable development of genetical and protein analysis. However, we are apt to lose opportunities to observe about the disease as a whole feature. In this article, we describe the inflammatory process from synovial inflammation to cartilage and bone destruction. We notice that there are many problems to be solved in rheumatoid arthritis (RA) from the point of inflammatory process. It is often needed for us to stand still and look over the whole features of disease.
authors.affiliation: Iwate Medical University, School of Medicine, Department of Pathology.
authors.forename: Miwa
authors.initials: M
authors.lastname: Uzuki
authors.forename: Takashi
authors.initials: T
authors.lastname: Sawai
authors.forename: Yoshiko
authors.initials: Y
authors.lastname: Sasaki
mesh_terms: D000818:Animals; D017209:Apoptosis; D001172:Arthritis, Rheumatoid / Q000209:etiology / Q000473:pathology*; D001842:Bone and Bones / Q000473:pathology*; D002358:Cartilage, Articular / Q000473:pathology*; D053222:Fas Ligand Protein; D006801:Humans; D007596:Joints / Q000473:pathology*; D020782:Matrix Metalloproteinases; D009569:Nitric Oxide; D053245:RANK Ligand; D013583:Synovial Membrane / Q000473:pathology; D014409:Tumor Necrosis Factor-alpha
chemical_list: D053222:Fas Ligand Protein; D053245:RANK Ligand; D014409:Tumor Necrosis Factor-alpha; D009569:Nitric Oxide; D020782:Matrix Metalloproteinases