title: Ecdysteroids from Serratula wolffii roots.
abstract: Two new natural ecdysteroids, 20,22-didehydrotaxisterone (1) and 1-hydroxy-20,22-didehydrotaxisterone (2), were isolated from the roots of Serratula wolffii. Their structures were elucidated by 1D and 2D NMR spectroscopy and mass spectrometry. The biological activities of these compounds were determined via oral aphid (Acyrthosiphon pisum (Harris)) tests. Compound 1 was inactive and compound 2 exhibited very low toxicity in the oral aphid test. The activities of these two ecdysteroids were in agreement with those of other 22-deoxyecdysteroids.
authors.affiliation: Department of Pharmacognosy, University of Szeged, Szeged, Eötvös utca 6, H-6720, Hungary.
authors.forename: Erika
authors.initials: E
authors.lastname: Liktor-Busa
authors.forename: András
authors.initials: A
authors.lastname: Simon
authors.forename: Gábor
authors.initials: G
authors.lastname: Tóth
authors.forename: Gabor
authors.initials: G
authors.lastname: Fekete
authors.forename: Zoltán
authors.initials: Z
authors.lastname: Kele
authors.forename: Mária
authors.initials: M
authors.lastname: Báthori
mesh_terms: D000818:Animals; D001042:Aphids / Q000187:drug effects; D019659:Asteraceae / Q000737:chemistry*; D026461:Ecdysteroids / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D006814:Hungary; D007814:Larva / Q000187:drug effects; D015394:Molecular Structure; D018517:Plant Roots / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*
chemical_list: C521038:1-hydroxy-20,22-didehydrotaxisterone; C521037:20,22-didehydrotaxisterone; D026461:Ecdysteroids