title: Multidrug-resistant tuberculous meningitis in an HIV-positive patient: a challenging disease.
abstract: We report two cases of disseminated multidrug-resistant tuberculosis with meningitis in HIV-positive patients, who were both recent emigrants from sub-Saharan Africa. Our two cases highlight new challenges in the care of HIV and tuberculosis coinfection including early diagnosis and treatment of multidrug-resistant tuberculosis that is spreading.
authors.affiliation: Service des Maladies Infectieuses et Tropicales A, Paris, France. agnes.meybeck@caramail.com
authors.forename: A
authors.initials: A
authors.lastname: Meybeck
authors.forename: J
authors.initials: J
authors.lastname: Calbet
authors.forename: R
authors.initials: R
authors.lastname: Ruimy
authors.forename: K
authors.initials: K
authors.lastname: Mashri
authors.forename: M
authors.initials: M
authors.lastname: Jachym
authors.forename: V
authors.initials: V
authors.lastname: Joly
authors.forename: P
authors.initials: P
authors.lastname: Yeni
mesh_terms: D000328:Adult; D000995:Antitubercular Agents / Q000627:therapeutic use; D002163:Cameroon / Q000208:ethnology; D024901:Drug Resistance, Multiple, Bacterial; D004641:Emigration and Immigration; D005260:Female; D005602:France; D005869:Ghana / Q000208:ethnology; D006679:HIV Seropositivity / Q000150:complications*; D006801:Humans; D014390:Tuberculosis, Meningeal / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy*; D018088:Tuberculosis, Multidrug-Resistant / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy*
chemical_list: D000995:Antitubercular Agents