title: Optical coherence tomography following photodynamic therapy with verteporfin for subfoveal predominantly classic choroidal neovascularization.
abstract: We characterized the changes in optical coherence tomography following photodynamic therapy (PDT) for subfoveal predominantly classic choroidal neovascularization (CNV) in 26 eyes before, 1 week after, and 3 months after treatment. There appears to be a temporal decrease in central retinal thickness, increase in central retinal pigment epithelium/CNV complex thickness, and decrease in subretinal fluid following PDT, making it a useful adjunct in the management of CNV due to of age-related macular degeneration.
authors.affiliation: Wills Eye Hospital, Philadelphia, PA, USA.
authors.forename: Carl H
authors.initials: CH
authors.lastname: Park
authors.forename: Bradley T
authors.initials: BT
authors.lastname: Smith
authors.forename: Mila
authors.initials: M
authors.lastname: Oh
authors.forename: Sharon
authors.initials: S
authors.lastname: Fekrat
mesh_terms: D000368:Aged; D020256:Choroidal Neovascularization / Q000175:diagnosis* / Q000188:drug therapy* / Q000209:etiology / Q000503:physiopathology; D005122:Exudates and Transudates / Q000378:metabolism; D005584:Fovea Centralis; D006801:Humans; D008268:Macular Degeneration / Q000150:complications; D008269:Macular Edema / Q000175:diagnosis / Q000209:etiology; D010778:Photochemotherapy; D017319:Photosensitizing Agents / Q000627:therapeutic use*; D010857:Pigment Epithelium of Eye / Q000473:pathology; D011166:Porphyrins / Q000627:therapeutic use*; D012160:Retina / Q000378:metabolism / Q000473:pathology; D013997:Time Factors; D041623:Tomography, Optical Coherence; D016896:Treatment Outcome; D000077362:Verteporfin; D014792:Visual Acuity
chemical_list: D017319:Photosensitizing Agents; D011166:Porphyrins; D000077362:Verteporfin