title: [Research advance of role of inhibitor of differentiation 2 in skeletal muscle regeneration].
abstract: OBJECTIVE
  To review researches of the role of inhibitor of differentiation 2(Id2) in skeletal muscle regeneration.
  
  
  METHODS
  The latest original literature concerning Id2 and its role in skeletal muscle regeneration was extensively reviewed.
  
  
  RESULTS
  Id2 could form heterodimers by combining with E protein to prevent myogenic regulatory factors (MRFs) forming heterodimers by combining with E protein, to inhibit the transcription activity of MRFs and differentiation of skeletal muscle cell.
  
  
  CONCLUSIONS
  Id2 plays an important role in skeletal muscle regeneration.
authors.affiliation: Department of Anatomy, Southern Medical University, Guangdong Provincial Key Laboratory of Tissue Construction and Inspection, Guangzhou Guangdong, 510515, PR China. lai7890@sohu.com
authors.forename: Guihua
authors.initials: G
authors.lastname: Lai
authors.forename: Xiaozhong
authors.initials: X
authors.lastname: Qiu
authors.forename: Jun
authors.initials: J
authors.lastname: Ouyang
mesh_terms: D000818:Animals; D002454:Cell Differentiation; D049109:Cell Proliferation; D006801:Humans; D051797:Inhibitor of Differentiation Protein 2 / Q000502:physiology*; D051379:Mice; D018482:Muscle, Skeletal / Q000166:cytology / Q000293:injuries / Q000502:physiology*; D032446:Myoblasts / Q000166:cytology / Q000502:physiology; D018006:Myogenic Regulatory Factors / Q000037:antagonists & inhibitors*; D012038:Regeneration
chemical_list: D051797:Inhibitor of Differentiation Protein 2; D018006:Myogenic Regulatory Factors