The phosphotransferase system formed by PtsP, PtsO, and PtsN proteins controls production of polyhydroxyalkanoates in Pseudomonas putida.
The genome of Pseudomonas putida KT2440 encodes five proteins of the phosphoenolpyruvate-carbohydrate phosphotransferase system. Two of these (FruA and FruB) form a dedicated system for fructose intake, while enzyme I(Ntr) (EI(Ntr); encoded by ptsP), NPr (ptsO), and EII(Ntr) (ptsN) act in concert to control the intracellular accumulation of polyhydroxyalkanoates, a typical product of carbon overflow.
Velázquez
Francisco
F
Centro Nacional de Biotecnología-CSIC, Campus UAM-Cantoblanco, Madrid 28049, Spain.
Pflüger
Katharina
K
Cases
Ildefonso
I
De Eugenio
Laura I
LI
de Lorenzo
Víctor
V
D001426:Bacterial Proteins / Q000235:genetics / Q000378:metabolism*; D002264:Carboxylic Acids / Q000378:metabolism*; D017353:Gene Deletion; D016254:Mutagenesis, Insertional; D010731:Phosphoenolpyruvate Sugar Phosphotransferase System / Q000235:genetics / Q000378:metabolism; D016958:Pseudomonas putida / Q000235:genetics / Q000254:growth & development / Q000378:metabolism*
D001426:Bacterial Proteins; D002264:Carboxylic Acids; C423631:PtsN protein, Pseudomonas putida; D010731:Phosphoenolpyruvate Sugar Phosphotransferase System