title: Non-Hodgkin's lymphoma of the knee diagnosed by arthroscopy.
abstract: We report a case of non-Hodgkin's lymphoma of the knee diagnosed by arthroscopy in an otherwise healthy, active 31-year-old woman. Plain radiographs were unremarkable and magnetic resonance imaging findings indicated the presence of a posterior horn medial meniscal tear. The patient underwent arthroscopy for a planned partial medial meniscectomy. However, on joint visualization, hyperemic hypertrophic synovitis was found. Tissue samples were collected and sent for histopathologic testing that revealed diffuse large B cells. The patient was referred to the oncology department where 2 lesions on her lung were also found. Malignant disease should be in the mindset of the orthopaedic surgeon when a patient presents with constant pain, an unusual history, atypical response to conventional treatment, or a diagnostic dilemma.
authors.affiliation: Department of Orthopaedic Surgery, Riverside Methodist Hospital, Columbus, Ohio, USA.
authors.forename: Joseph
authors.initials: J
authors.lastname: Mileti
authors.forename: Linda
authors.initials: L
authors.lastname: Mileti
authors.forename: Christopher
authors.initials: C
authors.lastname: Kaeding
mesh_terms: D000328:Adult; D001182:Arthroscopy / Q000379:methods*; D001707:Biopsy, Needle; D003937:Diagnosis, Differential; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007150:Immunohistochemistry; D007719:Knee Joint; D008228:Lymphoma, Non-Hodgkin / Q000175:diagnosis* / Q000628:therapy; D008279:Magnetic Resonance Imaging; D018570:Risk Assessment; D013585:Synovitis / Q000175:diagnosis*; D014057:Tomography, X-Ray Computed