title: [Study on human case of avian influenza in Guangzhou 2006 without causing human-to-human transmission among close contacts].
abstract: Study on human case of avian influenza in Guangzhou 2006 without causing human-to-human transmission
  
  
  OBJECTIVE
  To explore the possibility of transmission from a human case of avian influenza to his close contacts.
  
  
  METHODS
  Close contacts of the human case of avian influenza in Guangzhou 2006 were found out according to the definition and methods publicized by the Ministry of Health, People's Republic of China. Epidemiological investigation and medical observation were carried out. Serum antibodies were tested in some of the close contacts.
  
  
  RESULTS
  The avian influenza patient had never left Guangzhou in the month prior to disease onset. No contact history with dead or diseased poultry was found. A total of 56 close contacts, including his girl friend, relatives, friends and medical staff who had taken care of him, were brought under medical observation for 7 days but none of them showed signs of infection.
  
  
  CONCLUSIONS
  Unlike SARS, direct contact with patient contracted with avian influenza at the end of incubation period and in the stage of illness through flying droplets, saliva, mucous membrane and skin injuries will not lead to human-to-human transmission, indicating the virus' ability to pass from human to human is limited.
authors.affiliation: Guangzhou Center for Disease Control and Prevention, Guangzhou 510080, China.
authors.forename: Yu-Lin
authors.initials: YL
authors.lastname: Wang
authors.forename: Peng-Zhe
authors.initials: PZ
authors.lastname: Qin
authors.forename: Yu-Fei
authors.initials: YF
authors.lastname: Liu
authors.forename: Xin-Wei
authors.initials: XW
authors.lastname: Wu
authors.forename: Yang
authors.initials: Y
authors.lastname: Liu
authors.forename: Jian-Wen
authors.initials: JW
authors.lastname: Fan
authors.forename: Liu-Hua
authors.initials: LH
authors.lastname: Zhan
authors.forename: Ju-Xuan
authors.initials: JX
authors.lastname: Guo
authors.forename: Xiao-Shuang
authors.initials: XS
authors.lastname: Chen
authors.forename: Li-Yun
authors.initials: LY
authors.lastname: Jiang
authors.forename: Duan-Hua
authors.initials: DH
authors.lastname: Zhou
authors.forename: Biao
authors.initials: B
authors.lastname: Di
authors.forename: Ming
authors.initials: M
authors.lastname: Wang
mesh_terms: D000818:Animals; D002681:China; D016358:Contact Tracing; D005260:Female; D006801:Humans; D007251:Influenza, Human / Q000635:transmission*; D008297:Male