title: Spread in an Italian hospital of a clonal Acinetobacter baumannii strain producing the TEM-92 extended-spectrum beta-lactamase.
abstract: Clinical isolates of Acinetobacter baumannii (n = 470) were collected during a 7-year period and investigated for the genetic determinants of resistance to expanded-spectrum beta-lactams. Thirty-one isolates produced the TEM-92 extended-spectrum beta-lactamase (ESBL) and were clonally related. This is the first report of A. baumannii producing a TEM-type ESBL.
authors.affiliation: Laboratorio di Microbiologia, Ospedale di Circolo and Università dell'Insubria, Viale Borri 57, 21100 Varese, Italy. aendimiani@tin.it
authors.forename: Andrea
authors.initials: A
authors.lastname: Endimiani
authors.forename: Francesco
authors.initials: F
authors.lastname: Luzzaro
authors.forename: Roberta
authors.initials: R
authors.lastname: Migliavacca
authors.forename: Elisabetta
authors.initials: E
authors.lastname: Mantengoli
authors.forename: Andrea M
authors.initials: AM
authors.lastname: Hujer
authors.forename: Kristine M
authors.initials: KM
authors.lastname: Hujer
authors.forename: Laura
authors.initials: L
authors.lastname: Pagani
authors.forename: Robert A
authors.initials: RA
authors.lastname: Bonomo
authors.forename: Gian Maria
authors.initials: GM
authors.lastname: Rossolini
authors.forename: Antonio
authors.initials: A
authors.lastname: Toniolo
mesh_terms: D000151:Acinetobacter Infections / Q000453:epidemiology / Q000382:microbiology / Q000635:transmission; D040981:Acinetobacter baumannii / Q000145:classification / Q000187:drug effects / Q000201:enzymology / Q000235:genetics*; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D003428:Cross Infection / Q000453:epidemiology / Q000382:microbiology / Q000635:transmission; D006801:Humans; D007558:Italy / Q000453:epidemiology; D008826:Microbial Sensitivity Tests; D018440:beta-Lactam Resistance / Q000235:genetics; D001618:beta-Lactamases / Q000096:biosynthesis* / Q000737:chemistry / Q000145:classification / Q000235:genetics*; D047090:beta-Lactams / Q000494:pharmacology
chemical_list: D000900:Anti-Bacterial Agents; D047090:beta-Lactams; D001618:beta-Lactamases