title: Using multiple cause-of-death data to investigate associations and causality between conditions listed on the death certificate.
abstract: Death rarely results from only one cause, and it can be caused by a variety of factors. Multiple cause-of-death data files can list as many as 20 contributing causes of death in addition to the reported underlying cause of death. Analysis of multiple cause-of-death data can provide information on associations between causes of death, revealing common combinations of events or conditions which lead to death. Additionally, physicians report the causal train of events through which they believe that different conditions or events may have led to each other and ultimately caused death. In this paper, the authors discuss methods used in studying associations between reported causes of death and in investigating commonly reported causal pathways between events or conditions listed on the death certificate.
authors.affiliation: Data Collection and Analysis Unit, Los Angeles County Department of Public Health, Los Angeles, CA 90012, USA. mredelings@ph.lacounty.gov
authors.forename: Matthew D
authors.initials: MD
authors.lastname: Redelings
authors.forename: Matthew
authors.initials: M
authors.lastname: Wise
authors.forename: Frank
authors.initials: F
authors.lastname: Sorvillo
mesh_terms: D016022:Case-Control Studies; D015984:Causality; D002423:Cause of Death; D015897:Comorbidity; D003644:Death Certificates; D006801:Humans; D038801:International Classification of Diseases; D003668:Pressure Ulcer / Q000150:complications / Q000401:mortality; D018805:Sepsis / Q000150:complications / Q000401:mortality; D014481:United States