title: Asymmetric addition of 1-ethynylcyclohexene to both aromatic and heteroaromatic ketones catalyzed by a chiral Schiff base-zinc complex.
abstract: The evaluation of a chiral Schiff base ligand in the zinc-catalyzed asymmetric addition of 1-ethynylcyclohexene to both aromatic and heteroaromatic ketones is reported (with up to 83% enantioselectivity and up to 88% isolated yield).
authors.affiliation: Department of Biochemistry and Molecular Biology, School of Life Sciences, and State key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou, Gansu 730000, China.
authors.forename: Quan
authors.initials: Q
authors.lastname: Wang
authors.forename: Bangzhi
authors.initials: B
authors.lastname: Zhang
authors.forename: Guowen
authors.initials: G
authors.lastname: Hu
authors.forename: Chao
authors.initials: C
authors.lastname: Chen
authors.forename: Qinyang
authors.initials: Q
authors.lastname: Zhao
authors.forename: Rui
authors.initials: R
authors.lastname: Wang
mesh_terms: D000438:Alcohols / Q000138:chemical synthesis* / Q000737:chemistry; D000480:Alkynes / Q000737:chemistry*; D002384:Catalysis; D003510:Cyclohexanes / Q000737:chemistry*; D007659:Ketones / Q000737:chemistry*; D008024:Ligands; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D013237:Stereoisomerism; D015032:Zinc / Q000737:chemistry*
chemical_list: D000438:Alcohols; D000480:Alkynes; D003510:Cyclohexanes; D007659:Ketones; D008024:Ligands; D009942:Organometallic Compounds; C522558:1-ethynylcyclohexene; D015032:Zinc