Convergent chemical synthesis and crystal structure of a 203 amino acid "covalent dimer" HIV-1 protease enzyme molecule.
Torbeev
Vladimir Yu
VY
Department of Chemistry, Institute for Biophysical Dynamics, Gordon Center for Integrative Science, The University of Chicago, 929 East 57th Street, Chicago, IL 60637, USA.
Kent
Stephen B H
SB
D000596:Amino Acids / Q000737:chemistry*; D018360:Crystallography, X-Ray; D019281:Dimerization; D016333:HIV Protease / Q000138:chemical synthesis* / Q000737:chemistry*; D017320:HIV Protease Inhibitors / Q000737:chemistry; D009842:Oligopeptides / Q000737:chemistry; D011487:Protein Conformation; D017434:Protein Structure, Tertiary; D013329:Structure-Activity Relationship; D013997:Time Factors
D000596:Amino Acids; D017320:HIV Protease Inhibitors; D009842:Oligopeptides; C061946:MVT 101; D016333:HIV Protease