title: Aminocaproic-acid seal to reduce or prevent bleeding after liver biopsy.
abstract: This study investigates the efficacy of an aminocaproic-acid seal to prevent or reduce the risk of bleeding attendant to liver biopsies. The simple technique of occluding the biopsy tract by injecting 1-2 mL of aminocaproic acid, a fibrinolysis inhibitor, while withdrawing the biopsy sheath appears to reduce substantially the risk of delayed bleeding. The technique may be most useful if large core biopsy needles must be used to provide an adequate specimen.
authors.affiliation: Department of Radiology and Transplant Surgery, Tulane Health Science Center, USA.
authors.forename: Erich K
authors.initials: EK
authors.lastname: Lang
authors.forename: Leann
authors.initials: L
authors.lastname: Myers
authors.forename: Douglas
authors.initials: D
authors.lastname: Slakey
authors.forename: Brian
authors.initials: B
authors.lastname: Rogers
authors.forename: Melissa
authors.initials: M
authors.lastname: Brammer
authors.forename: F
authors.initials: F
authors.lastname: Regenstein
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000614:Aminocaproates / Q000008:administration & dosage*; D000933:Antifibrinolytic Agents / Q000008:administration & dosage*; D001706:Biopsy / Q000009:adverse effects* / Q000295:instrumentation*; D002648:Child; D002675:Child, Preschool; D002908:Chronic Disease; D004867:Equipment Design; D005260:Female; D006489:Hemostatic Techniques; D006801:Humans; D008099:Liver / Q000473:pathology; D008107:Liver Diseases / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D019106:Postoperative Hemorrhage / Q000209:etiology / Q000517:prevention & control*; D012189:Retrospective Studies
chemical_list: D000614:Aminocaproates; D000933:Antifibrinolytic Agents