title: Effects of implant design parameters on fluid convection, potentiating third-body debris ingress into the bearing surface during THA impingement/subluxation.
abstract: Aseptic loosening from polyethylene wear debris is the leading cause of failure for metal-on-polyethylene total hip implants. Third-body debris ingress to the bearing space results in femoral head roughening and acceleration of polyethylene wear. How third-body particles manage to enter the bearing space between the closely conforming articulating surfaces of the joint is not well understood. We hypothesize that one such mechanism is from convective fluid transport during subluxation of the total hip joint. To test this hypothesis, a three-dimensional (3D) computational fluid dynamics (CFD) model was developed and validated, to quantify fluid ingress into the bearing space during a leg-cross subluxation event. The results indicated that extra-articular joint fluid could be drawn nearly to the pole of the cup with even very small separations of the femoral head (<0.60mm). Debris suspended near the equator of the cup at the site of maximum fluid velocity just before the subluxation began could be transported to within 11 degrees from the cup pole. Larger head diameters resulted in increased fluid velocity at all sites around the entrance to the gap compared to smaller head sizes, with fluid velocity being greatest along the anterosuperolateral cup edge, for all head sizes. Fluid pathlines indicated that suspended debris would reach similar angular positions in the bearing space regardless of head size. Increased inset of the femoral head into the acetabular cup resulted both in higher fluid velocity and in transport of third-body debris further into the bearing space.
authors.affiliation: Department of Orthopaedics and Rehabilitation, University of Iowa, Iowa City, IA 52242, USA.
authors.forename: Hannah J
authors.initials: HJ
authors.lastname: Lundberg
authors.forename: Douglas R
authors.initials: DR
authors.lastname: Pedersen
authors.forename: Thomas E
authors.initials: TE
authors.lastname: Baer
authors.forename: Marian
authors.initials: M
authors.lastname: Muste
authors.forename: John J
authors.initials: JJ
authors.lastname: Callaghan
authors.forename: Thomas D
authors.initials: TD
authors.lastname: Brown
mesh_terms: D000077:Acetabulum / Q000503:physiopathology; D003198:Computer Simulation; D017076:Computer-Aided Design; D004867:Equipment Design; D019544:Equipment Failure Analysis; D005270:Femur Head / Q000503:physiopathology; D005548:Foreign-Body Migration / Q000209:etiology* / Q000503:physiopathology*; D006617:Hip Dislocation / Q000209:etiology* / Q000503:physiopathology*; D006621:Hip Joint / Q000503:physiopathology*; D006622:Hip Prosthesis / Q000009:adverse effects*; D006801:Humans; D008954:Models, Biological; D013499:Surface Properties; D013582:Synovial Fluid