Role of malondialdehyde and superoxide dismutase in cataractogenesis.
Malondialdehyde (MDA) and superoxide dismutase (SOD) in lens and plasma of patients with age-related and myopic cataract were assessed. Higher levels of lens MDA in myopic patients showed a greater lipid peroxidation process than in patients with age-related cataract indicating higher oxidative stress in myopic lens. The difference in plasma MDA of myopic cataract and age-related cataract patients was not significant. The SOD level was lower in myopic patients than in patients with age-related cataract.
Bhatia
R P
RP
Institute of Medical Sciences, Banaras Hindu University, Varanasi, India. sri_rashmi@gawab.co
Rai
Ruchi
R
Rao
G R K
GR
D000375:Aging; D016022:Case-Control Studies; D002386:Cataract / Q000097:blood / Q000150:complications / Q000209:etiology* / Q000378:metabolism*; D006801:Humans; D007908:Lens, Crystalline / Q000378:metabolism*; D015227:Lipid Peroxidation; D008315:Malondialdehyde / Q000097:blood / Q000378:metabolism*; D009216:Myopia / Q000150:complications / Q000378:metabolism; D018384:Oxidative Stress; D013482:Superoxide Dismutase / Q000097:blood / Q000378:metabolism*
D008315:Malondialdehyde; D013482:Superoxide Dismutase