Primary spindle cell sarcoma of the vagina treated with neoadjuvant radiation and pelvic exenteration.
OBJECTIVE
Malignant neoplasms of the vagina are rare gynecologic tumors. Primary vaginal sarcomas are even more unusual lesions, representing fewer than 2% of malignant vaginal lesions.


METHODS
We present a case of a primary vaginal spindle cell sarcoma, treated with neoadjuvant radiation followed by total pelvic exenteration. The patient remains without evidence of disease 2 years after surgery.


CONCLUSIONS
The mainstay of treatment of vaginal sarcomas is surgical. Neoadjuvant radiation treatment may decrease surgical morbidity and lead to long-term cure.
Temkin
Sarah Madhu
SM
Department of Obstetrics and Gynecology, SUNY Downstate, Brooklyn, NY 11203, USA. sarah.temkin@gmail.com
Hellmann
Mira
M
Lee
Yi-Chun
YC
Abulafia
Ovadia
O
D005260:Female; D006470:Hemorrhage / Q000209:etiology* / Q000532:radiotherapy / Q000601:surgery; D006801:Humans; D008875:Middle Aged; D020360:Neoadjuvant Therapy / Q000379:methods*; D010385:Pelvic Exenteration; D018714:Radiotherapy, Adjuvant; D012509:Sarcoma / Q000150:complications / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery*; D016896:Treatment Outcome; D014625:Vaginal Neoplasms / Q000150:complications / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery*