title: Selective anterograde amnesia with thalamus and hippocampal lesions in neuro-Behcet's disease.
abstract: Anterograde amnesia and minimal retrograde amnesia with thalamic and hippocampal lesions in neuro-Behcet's disease is rare. A 50-year-old man presented with forgetfulness and severe memory disturbance after suffering multiple oral and genital aphthous ulcers with erythema nodosum. A neurological examination and a neuropsychological assessment revealed prominent anterograde memory impairment without focal neurological deficits. On brain MRI there were high signal intensity lesions involving right anterior thalamus, left posterior basal ganglia, and left hippocampus. This is a quite selective anterogrde memory deficit in a case of neuro-Behcet's disease caused by parenchymal lesions in the thalamus and hippocampus.
authors.affiliation: Department of Neurology, Dong-A University College of Medicine, Seo-gu, Busan 602-715, Republic of Korea. neuropark@dau.ac.kr
authors.forename: Kyung Won
authors.initials: KW
authors.lastname: Park
authors.forename: Jung Hwa
authors.initials: JH
authors.lastname: Seo
authors.forename: Go-Un
authors.initials: GU
authors.lastname: Yoon
mesh_terms: D020324:Amnesia, Anterograde / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D001479:Basal Ganglia / Q000473:pathology; D001528:Behcet Syndrome / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D001706:Biopsy; D001927:Brain Diseases / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D004292:Dominance, Cerebral / Q000502:physiology; D005500:Follow-Up Studies; D006624:Hippocampus / Q000473:pathology; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D011239:Prednisolone / Q000008:administration & dosage; D012867:Skin / Q000473:pathology; D013786:Thalamic Diseases / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D013788:Thalamus / Q000473:pathology
chemical_list: D007166:Immunosuppressive Agents; D011239:Prednisolone