title: A practical Buchwald-Hartwig amination of 2-bromopyridines with volatile amines.
abstract: A practical Buchwald-Hartwig amination of 2-bromopyridines with volatile amines is developed in sealed tubes. The method provides an expedient entry to a variety of secondary and tertiary aminopyridines that are otherwise not readily synthesized.
authors.affiliation: Department of Chemistry, Michigan Laboratories, Pfizer Global Research & Development, Ann Arbor, Michigan 48105, USA. jack.li@pfizer.com
authors.forename: Jie Jack
authors.initials: JJ
authors.lastname: Li
authors.forename: Zhi
authors.initials: Z
authors.lastname: Wang
authors.forename: Lorna H
authors.initials: LH
authors.lastname: Mitchell
mesh_terms: D000588:Amines / Q000737:chemistry*; D002625:Chemistry, Organic / Q000379:methods*; D011725:Pyridines / Q000737:chemistry; D014835:Volatilization
chemical_list: D000588:Amines; D011725:Pyridines; C023666:pyridine