title: The comparison of Montgomery and Asberg Depression Rating Scale (MADRS thai) to diagnostic and statistical manual of mental disorders (DSM) and to Hamilton Rating Scale for Depression (HRSD): validity and reliability.
abstract: OBJECTIVE
  To assess the validity and reliability of the Montgomery and Asberg Depression Rating Scale (MADRS Thai) by comparing DSM-IV TR criteria and Hamilton Rating Scale for Depression (HRSD).
  
  
  METHODS
  Descriptive study. Subjects were recruited from the psychiatric out-patient clinic Siriraj Hospital. Subjects were assessed by MADRS Thai version and clinical interview.
  
  
  RESULTS
  Opinion from psychiatric and social science experts, evaluating 13 study cases and 2 7 control cases, compared to the Global Assessment Scale (GAS) and to the changed scale of HRSD.
  Inter-rater and Intra-rater reliability and Internal consistency.
  
  
  RESULTS
  Content validity is above 0.5 except the item oflnner tension, Lassitude and Inablilty to feel. Criterion validity when compared to DSM-IV TR or HRSD, the sensitivity, specificity, PPV and NPV were all 100%. Pearson correlation coefficients sensitive to change were -0. 49 (p -value = 0. 11) and 0. 679 (p-value = 0. 025) when compared to 1) DSM-IV TR and 2) HRSD, respectively. ICC oflnter-rater and Intra-rater reliability were both 0.99 when compared to either 1) DSM-IV TR or 2) HRSD. Cronbach 's alpha of Internal consistency was 0. 96 and 0. 92 when compared to 1) DSM-IV TR and 2) HRSD, respectively.
  
  
  CONCLUSIONS
  The result suggested that the Thai version of the Montgomery and Asberg Depression Rating Scale had a very good validity and reliability. Therefore, it can be used as a diagnostic test in Thai depressed patients.
authors.affiliation: Division of Psychiatry, Saraburi Hospital, Saraburi 18000, Thailand. Sirisatt@yahoo.com
authors.forename: Sirina
authors.initials: S
authors.lastname: Satthapisit
authors.forename: Naiyana
authors.initials: N
authors.lastname: Posayaanuwat
authors.forename: Chadapim
authors.initials: C
authors.lastname: Sasaluksananont
authors.forename: Titawee
authors.initials: T
authors.lastname: Kaewpornsawan
authors.forename: Supachoke
authors.initials: S
authors.lastname: Singhakun
mesh_terms: D000368:Aged; D003863:Depression / Q000175:diagnosis*; D039721:Diagnostic and Statistical Manual of Mental Disorders; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015588:Observer Variation; D011581:Psychological Tests; D015203:Reproducibility of Results; D013785:Thailand