title: [Discoid lupus erythematosus with eyelid involvement. A series of nine patients].
abstract: BACKGROUND
  Discoid lupus erythematosus (DLE) is a chronic autoimmune skin disease that usually affects the sun-exposed skin. Palpebral involvement occurs uncommonly.
  
  
  METHODS
  The goal of our study was to present the clinical and therapeutic features of a series of nine patients with discoid lupus erythematosus with eyelid involvement.
  
  
  RESULTS
  Lesions of discoid lupus were more frequent in the lower eyelids (seven cases). The palpebral location was the only manifestation of the disease in a 34-year-old woman. In the other cases, cutaneous lesions of typical discoid lupus were noted. Seven patients responded to therapy with antimalarial drugs associated with local corticosteroids and photoprotection.
  
  
  CONCLUSIONS
  Eyelid lesions of discoid lupus erythematosus are rare. Involvement of the lower eyelids is more common. It is important to diagnose discoid lupus of the eyelids because misdiagnosis (isolated form) can delay treatment and cause deformities. The treatment is systemic antimalarial drugs, which have an excellent clinical response.
authors.affiliation: Service de Dermatologie, Sfax, Tunisie. madiha.mseddi@laposte.net
authors.forename: M
authors.initials: M
authors.lastname: Mseddi
authors.forename: S
authors.initials: S
authors.lastname: Marrekchi
authors.forename: T J
authors.initials: TJ
authors.lastname: Meziou
authors.forename: D
authors.initials: D
authors.lastname: Sellami
authors.forename: B
authors.initials: B
authors.lastname: Kammoun
authors.forename: J
authors.initials: J
authors.lastname: Feki
authors.forename: A
authors.initials: A
authors.lastname: Zahaf
authors.forename: H
authors.initials: H
authors.lastname: Turki
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D000962:Antimalarials / Q000627:therapeutic use; D001762:Blepharitis / Q000188:drug therapy / Q000209:etiology / Q000473:pathology / Q000628:therapy; D005135:Eye Protective Devices; D005141:Eyelid Diseases / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology / Q000628:therapy; D005143:Eyelids / Q000473:pathology*; D005260:Female; D006801:Humans; D008179:Lupus Erythematosus, Discoid / Q000188:drug therapy / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D013792:Thalidomide / Q000627:therapeutic use
chemical_list: D000305:Adrenal Cortex Hormones; D000962:Antimalarials; D013792:Thalidomide