Mitochondrial myopathy complicated by eating disorder: a case report highlighting the potential interaction of genetic, metabolic, and psychodynamic factors.
A case is presented of a 56-year-old woman with a history of an eating disorder that preceded recognition of a mitochondrial myopathy. The possibility exists that her eating disorder was causally related to a more fundamental defect in mitochondrial oxidative metabolism. This case report highlights the phenotypic variability of mitochondrial myopathies. An increased risk of eating disorder may be associated with drugs that interfere with mitochondrial oxidative respiration.
Deutsch
Stephen I
SI
Mental Health Service Line (116A), Department of Veterans Affairs Medical Center, Washington, DC 20422, USA. stephen.deutsch@med.va.gov
Rosse
Richard B
RB
Yaseen
Mohammad
M
Schulman
Howard M
HM
Abraham
Samathanam
S
D001066:Appetite / Q000235:genetics; D052018:Bulimia Nervosa / Q000150:complications* / Q000235:genetics / Q000523:psychology; D004272:DNA, Mitochondrial / Q000235:genetics; D003937:Diagnosis, Differential; D004040:Dietary Carbohydrates / Q000008:administration & dosage; D005260:Female; D020022:Genetic Predisposition to Disease / Q000235:genetics; D006801:Humans; D017243:MERRF Syndrome / Q000150:complications* / Q000235:genetics / Q000523:psychology; D008875:Middle Aged; D010641:Phenotype
D004272:DNA, Mitochondrial; D004040:Dietary Carbohydrates