title: Effects of L-, D-, and DL-carnitine on morphometric parameters of skeletal muscle and exercise performance of laboratory animals receiving carnitine-deficient diet.
abstract: Serum concentration of L-carnitine, the mean thickness of the skeletal muscle fiber, and exercise performance in the forced swimming test decreased in rats receiving a carnitine-deficient diet. Treatment with L-carnitine compensated for carnitine deficiency, while racemate and D-stereoisomer did not increase its level. L-Carnitine, but not racemate and D-stereoisomer, promoted recovery of the skeletal muscle fiber thickness and exercise performance of rats.
authors.affiliation: Institute of Pharmacology, Volgograd State Medical University. farm@interdacom.ru
authors.forename: A A
authors.initials: AA
authors.lastname: Spasov
authors.forename: I N
authors.initials: IN
authors.lastname: Iezhitsa
authors.forename: M S
authors.initials: MS
authors.lastname: Kravchenko
authors.forename: V B
authors.initials: VB
authors.lastname: Pisarev
authors.forename: G L
authors.initials: GL
authors.lastname: Snigur
mesh_terms: D000818:Animals; D002331:Carnitine / Q000172:deficiency* / Q000494:pharmacology*; D008297:Male; D023421:Models, Animal; D018482:Muscle, Skeletal / Q000187:drug effects / Q000502:physiology*; D010805:Physical Conditioning, Animal; D051381:Rats; D013237:Stereoisomerism; D013550:Swimming
chemical_list: D002331:Carnitine