title: A multicenter reliability study of extremity-magnetic resonance imaging in the longitudinal evaluation of rheumatoid arthritis.
abstract: There are limited data on the reliability of extremity magnetic resonance imaging (E-MRI) in the longitudinal evaluation of rheumatoid arthritis (RA). Our aim was to assess the interreader reliability of the OMERACT RA MRI score in the assessment of change in disease activity and bone erosion scores using 0.2 T E-MRI hand and wrist images from 2 timepoints, evaluated by 3 readers at different international centers. The intraclass correlation coefficients and smallest detectable difference results for the change scores were generally good for erosions and synovitis, but were not acceptable for bone edema. Overall, E-MRI demonstrated ability to detect change comparable to that reported for high-field MRI for erosion and synovitis.
authors.affiliation: Academic Unit of Musculoskeletal Disease, University of Leeds, Leeds, UK. p.conaghan@leeds.ac.uk
authors.forename: Philip G
authors.initials: PG
authors.lastname: Conaghan
authors.forename: Bo
authors.initials: B
authors.lastname: Ejbjerg
authors.forename: Marissa
authors.initials: M
authors.lastname: Lassere
authors.forename: Paul
authors.initials: P
authors.lastname: Bird
authors.forename: Charles
authors.initials: C
authors.lastname: Peterfy
authors.forename: Paul
authors.initials: P
authors.lastname: Emery
authors.forename: Fiona
authors.initials: F
authors.lastname: McQueen
authors.forename: Espen
authors.initials: E
authors.lastname: Haavardsholm
authors.forename: Philip
authors.initials: P
authors.lastname: O'Connor
authors.forename: John
authors.initials: J
authors.lastname: Edmonds
authors.forename: Harry
authors.initials: H
authors.lastname: Genant
authors.forename: Mikkel
authors.initials: M
authors.lastname: Østergaard
mesh_terms: D000251:Adenosine Triphosphatases; D000328:Adult; D000368:Aged; D001172:Arthritis, Rheumatoid / Q000175:diagnosis / Q000473:pathology*; D004265:DNA Helicases; D006801:Humans; D008137:Longitudinal Studies; D008279:Magnetic Resonance Imaging / Q000295:instrumentation / Q000379:methods*; D008662:Metacarpophalangeal Joint / Q000473:pathology*; D008875:Middle Aged; D015588:Observer Variation; D015203:Reproducibility of Results; D012720:Severity of Illness Index; D013585:Synovitis / Q000175:diagnosis / Q000473:pathology*; D014955:Wrist Joint / Q000473:pathology*
chemical_list: D000251:Adenosine Triphosphatases; C484263:HELB protein, human; D004265:DNA Helicases