title: Adenoviral pneumonia during etanercept treatment in a patient with rheumatoid arthritis.
abstract: Inhibitors of tumor necrosis factor-alpha (TNF-alpha) have been approved for treating rheumatoid arthritis. As one of the biological response modifiers, etanercept has also been used in the treatment of psoriatic arthritis and inflammatory bowel disease. While etanercept is effective, certain infectious complications, such as tuberculosis, fungus, and cytomegalovirus, have been reported. We report the first Korean case of adenoviral pneumonia in a 55-year-old female who developed disseminated adenoviral infection following etanercept treatment, which resolved after anti-TNF-alpha discontinuation.
authors.affiliation: Department of Internal Medicine, College of Medicine, Ewha Womans University, Seoul, Korea.
authors.forename: Min-Jung
authors.initials: MJ
authors.lastname: Kang
authors.forename: Myung-Sin
authors.initials: MS
authors.lastname: Kim
authors.forename: Eun-Hwa
authors.initials: EH
authors.lastname: Choi
authors.forename: Kyoung-Eun
authors.initials: KE
authors.lastname: Lee
authors.forename: You-Kyoung
authors.initials: YK
authors.lastname: Kim
authors.forename: Hee-Jung
authors.initials: HJ
authors.lastname: Choi
mesh_terms: D000258:Adenovirus Infections, Human / Q000209:etiology* / Q000276:immunology; D000911:Antibodies, Monoclonal / Q000009:adverse effects* / Q000276:immunology; D018501:Antirheumatic Agents / Q000009:adverse effects* / Q000276:immunology; D001172:Arthritis, Rheumatoid / Q000188:drug therapy*; D000068800:Etanercept; D005260:Female; D006801:Humans; D016867:Immunocompromised Host / Q000187:drug effects; D007074:Immunoglobulin G / Q000009:adverse effects* / Q000276:immunology; D008875:Middle Aged; D018124:Receptors, Tumor Necrosis Factor / Q000276:immunology; D011993:Recombinant Fusion Proteins / Q000276:immunology; D012307:Risk Factors
chemical_list: D000911:Antibodies, Monoclonal; D018501:Antirheumatic Agents; D007074:Immunoglobulin G; D018124:Receptors, Tumor Necrosis Factor; D011993:Recombinant Fusion Proteins; D000068800:Etanercept