Peptide based malaria vaccine development: personal considerations.
A brief historical account of synthetic peptide approach to malaria vaccine discovery and development, and recent accomplishments is presented. Application of this approach to high-throughput antigen discovery using the genome information is described. The need of a truly global effort and cooperation to defeat malaria is also discussed.
Corradin
Giampietro
G
Biochemistry Department, University of Lausanne, Chemin des Boveresses 155, 1066 Epalinges, Switzerland. giampietro.corradin@unil.ch
D000818:Animals; D015195:Drug Design; D006801:Humans; D008288:Malaria / Q000517:prevention & control*; D017780:Malaria Vaccines; D010455:Peptides / Q000138:chemical synthesis / Q000276:immunology*; D010961:Plasmodium / Q000276:immunology*; D015800:Protozoan Proteins / Q000276:immunology*; D014614:Vaccines, Synthetic
D017780:Malaria Vaccines; D010455:Peptides; D015800:Protozoan Proteins; D014614:Vaccines, Synthetic