title: A preliminary fMRI study of the effects on cortical activation of the treatment of refractory auditory hallucinations with rTMS.
abstract: Three patients underwent fMRI during a word generation task before and after successful treatment of auditory hallucinations with rTMS and were compared to four control subjects. There was a significant increase and more normal task related brain activation in brain areas involved in language processing including left temporoparietal cortex after rTMS treatment.
authors.affiliation: Alfred Psychiatry Research Centre, The Alfred and Monash University Department of Psychological Medicine, Commercial Rd, Melbourne, Victoria 3004, Australia. paul.fitzgerald@med.monash.edu.au
authors.forename: Paul B
authors.initials: PB
authors.lastname: Fitzgerald
authors.forename: Anusha
authors.initials: A
authors.lastname: Sritharan
authors.forename: Jessica
authors.initials: J
authors.lastname: Benitez
authors.forename: Z Jeff
authors.initials: ZJ
authors.lastname: Daskalakis
authors.forename: Graeme
authors.initials: G
authors.lastname: Jackson
authors.forename: Jayashri
authors.initials: J
authors.lastname: Kulkarni
authors.forename: Gary F
authors.initials: GF
authors.lastname: Egan
mesh_terms: D000328:Adult; D000077582:Amisulpride; D014150:Antipsychotic Agents / Q000627:therapeutic use; D003024:Clozapine / Q000627:therapeutic use; D003131:Combined Modality Therapy; D005260:Female; D007839:Functional Laterality / Q000502:physiology; D006212:Hallucinations / Q000378:metabolism / Q000503:physiopathology / Q000628:therapy; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D010296:Parietal Lobe / Q000378:metabolism* / Q000503:physiopathology*; D011930:Reaction Time; D012559:Schizophrenia / Q000378:metabolism / Q000503:physiopathology / Q000628:therapy; D013469:Sulpiride / Q000031:analogs & derivatives / Q000627:therapeutic use; D013702:Temporal Lobe / Q000378:metabolism* / Q000503:physiopathology*; D050781:Transcranial Magnetic Stimulation / Q000379:methods*; D016896:Treatment Outcome
chemical_list: D014150:Antipsychotic Agents; D013469:Sulpiride; D000077582:Amisulpride; D003024:Clozapine