Nd:YAG laser iridotomy in the management of secondary glaucoma associated with Behçet's disease.
OBJECTIVE
To report the outcome of Nd:YAG laser iridotomy in the management of secondary glaucoma associated with Behçet's disease (BD).


METHODS
In this prospective study, Nd:YAG laser iridotomy was performed on eyes with secondary angle-closure and pupillary block glaucoma associated with BD. The pretreatment and post-treatment intraocular pressures (IOP) and the number of antiglaucoma medications were compared by Mann-Whitney U test.


RESULTS
The study consisted of 16 eyes of 11 patients (2 female, 9 male, mean age 39.2+/-8.9 years). Post-treatment follow-up ranged from 6 to 36 months (mean 13.8+/-8.9). The mean IOP was 21.6+/-2.5 mmHg on 2.5+/-0.6 medications before iridotomy. IOP reduced to 17.7+/-2.5 mmHg on 1+/-0.6 medications at the first month and 17.1+/-3.2 mmHg on 1.7+/-0.9 medications at the sixth month of treatment. The differences between IOP and number of antiglaucoma medications at baseline and at the sixth month of the treatment was statistically significant (p<0.00001). For four eyes trabeculectomy with mitomycin C and for one eye Ahmed valve implantation were performed in the follow-up period.


CONCLUSIONS
Nd:YAG laser iridotomy can provide reduction of IOP and the number of antiglaucoma medications in selected cases with secondary glaucoma associated with Behcet's disease.
Elgin
U
U
Ankara Ulucanlar Eye Research Hospital, 06490 Bahcelievler, Ankara, Turkey. ufukelgin@superonline.com
Berker
N
N
Batman
A
A
Soykan
E
E
D000328:Adult; D000959:Antihypertensive Agents / Q000627:therapeutic use; D001528:Behcet Syndrome / Q000150:complications*; D005260:Female; D005500:Follow-Up Studies; D020327:Glaucoma Drainage Implants; D015812:Glaucoma, Angle-Closure / Q000188:drug therapy / Q000209:etiology / Q000601:surgery*; D006801:Humans; D007429:Intraocular Pressure; D032801:Iridectomy / Q000379:methods*; D007498:Iris / Q000601:surgery*; D053685:Laser Therapy; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D014065:Tonometry, Ocular; D014130:Trabeculectomy; D016896:Treatment Outcome
D000959:Antihypertensive Agents