[Inhibition of radiographic progression in rheumatoid arthritis by anti-rheumatic drugs (DMARDs)].
From the results of recent randomized controlled clinical trials of disease modifying antirheumatic drugs (DMARDs), slowing radiographic progression has been documented with the use of methotrexate, leflunomide, salazusulfapyridine, IM gold, and cyclosporine. Although the effects of DMARDs is inferior to that of anti-tumor necrosis factor (TNF) agents, DMARDs can stop the progression of joint damage with the achievement of remission or good response.
Suzuki
Yasuo
Y
Tokai University School of Medicine, Department of Internal Medicine, Division of Rheumatology.
Wakabayashi
Takayuki
T
Saito
Eiko
E
Suwa
Akira
A
D018501:Antirheumatic Agents / Q000627:therapeutic use*; D001172:Arthritis, Rheumatoid / Q000000981:diagnostic imaging* / Q000188:drug therapy* / Q000473:pathology; D002986:Clinical Trials as Topic; D016572:Cyclosporine / Q000627:therapeutic use; D018450:Disease Progression; D006801:Humans; D007555:Isoxazoles; D007596:Joints / Q000473:pathology; D000077339:Leflunomide; D008727:Methotrexate / Q000627:therapeutic use; D011859:Radiography; D012074:Remission Induction; D012460:Sulfasalazine / Q000627:therapeutic use
D018501:Antirheumatic Agents; D007555:Isoxazoles; D012460:Sulfasalazine; D016572:Cyclosporine; D000077339:Leflunomide; D008727:Methotrexate