title: [Effect of long-term microgravity on the vestibular function].
abstract: Comprehensive computerized oculomotor testing was used to investigate the vestibular function in 9 Russian members of ISS crews 3-9 on days 1 (2), 4 (5) and 8 (9) of return from long-term stay in microgravity (126 to 195 days). The vestibular function was assessed by the static otolith-cervical-ocular reflex, dynamic otolith-cervical-ocular reactions, vestibular reactivity, and spontaneous oculomotor activity. The postflight investigations revealed functional disorders in the peripheral (an increased vestibular reactivity, absent or damped otolith-cervical-ocular reflex), and central (spontaneous typical and atypical nystagmus, gaze nystagmus) vestibular analyzer. The pattern and extent of vestibular disorders after long-term exposure in microgravity were individual by character; however, some of the vestibular reactions, including disappearance or considerable damping of the static otolith-cervical-ocular reflex, exaggerated vestibular reactivity and spontaneous eye movements, displayed consistency.
authors.forename: L N
authors.initials: LN
authors.lastname: Kornilova
authors.forename: V V
authors.initials: VV
authors.lastname: Temnikova
authors.forename: M I
authors.initials: MI
authors.lastname: Alekhina
authors.forename: I A
authors.initials: IA
authors.lastname: Naumov
authors.forename: V P
authors.initials: VP
authors.lastname: Borovikova
authors.forename: A G
authors.initials: AG
authors.lastname: Iakushev
authors.forename: E A
authors.initials: EA
authors.lastname: Muratova
authors.forename: A V
authors.initials: AV
authors.lastname: Vasin
mesh_terms: D000221:Adaptation, Ocular / Q000502:physiology*; D000328:Adult; D000337:Aerospace Medicine; D003198:Computer Simulation; D005500:Follow-Up Studies; D006801:Humans; D008875:Middle Aged; D009760:Nystagmus, Physiologic / Q000502:physiology*; D016273:Occupational Exposure; D012016:Reference Values; D013026:Space Flight; D013997:Time Factors; D014722:Vestibule, Labyrinth / Q000502:physiology*; D014893:Weightlessness