title: Kumkum-induced dermatitis: an analysis of 46 cases.
abstract: Kumkum is a commonly used cosmetic in India, traditionally based on turmeric powder, and its ingredients can cause various types of dermatosis. We undertook a study to characterize kumkum-induced dermatitis clinically and to identify by patch testing the allergens involved. In total, 46 patients with kumkum-induced dermatitis (mean age of these cases 46.5 years; female : male ratio 1.8 : 1) were investigated. The forehead was the most commonly involved site (31/46), followed by the glabellar area (16/46), hair parting (6/46), abdomen (5/46), and neck (3/46). Pigmented contact dermatitis was seen in 35 patients (76.1%), and allergic contact dermatitis in 11 patients (23.9%). In total, 25 patients were patch tested. The commonest positive allergic reaction was to thimerosal (18/25, 72%), followed by gallate mix (12/25, 48%). Para-phenylenediamine, Kathon CG, benzotriazol, tert-butyl hydroquinone and parabens gave a reaction for one patient each (1/25, 4%). Patch testing with kumkum was positive in 7 of 13 patients tested.
authors.affiliation: Department of Dermatology and Sexually Transmitted Diseases, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Pondicherry, India.
authors.forename: A K
authors.initials: AK
authors.lastname: Nath
authors.forename: D M
authors.initials: DM
authors.lastname: Thappa
mesh_terms: D000328:Adult; D000368:Aged; D004396:Coloring Agents / Q000009:adverse effects*; D030024:Curcuma / Q000009:adverse effects*; D017449:Dermatitis, Allergic Contact / Q000175:diagnosis*; D005260:Female; D006801:Humans; D007194:India; D008297:Male; D008875:Middle Aged; D010328:Patch Tests
chemical_list: D004396:Coloring Agents