title: Hypocitraturia despite potassium citrate tablet supplementation.
abstract: Citrate supplementation is widely used in the prevention of recurrent nephrolithiasis with hypocitraturia. Potassium citrate is the most commonly used citrate agent for this indication. In patients with chronic diarrheal syndromes, the absorption of potassium citrate can be affected. We describe a patient who presented with recurrent nephrolithiasis and chronic diarrhea and was found to have severe hypocitraturia despite citrate supplementation with potassium citrate tablets, likely due to inadequate gastrointestinal absorption of citrate from the slow-release wax-matrix tablets.
authors.affiliation: Department of Internal Medicine, Guthrie/Robert Packer Hospital, Sayre, Pennsylvania, USA. chetan_shenoy@yahoo.com
authors.forename: Chetan
authors.initials: C
authors.lastname: Shenoy
mesh_terms: D000328:Adult; D002951:Citrates / Q000652:urine*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D053040:Nephrolithiasis / Q000188:drug therapy* / Q000378:metabolism / Q000652:urine*; D019357:Potassium Citrate / Q000008:administration & dosage* / Q000627:therapeutic use; D019233:Retreatment; D012996:Solutions; D013607:Tablets / Q000009:adverse effects
chemical_list: D002951:Citrates; D012996:Solutions; D013607:Tablets; D019357:Potassium Citrate