title: Renal complications associated with human parvovirus B19 infection in early childhood.
abstract: A previously healthy two-year-old girl presented with proteinuria and macroscopic haematuria. Laboratory findings included haemolytic anaemia with thrombocytopenia. Interestingly, continuing reticulocytopenia was noted. Therefore an acute parvovirus B19 infection was suspected, which could be confirmed by serological and molecularbiological evidence. This case report underlines renal complications of parvovirus B19 infection in early childhood including haemolytic-uraemic syndrome (HUS)-like episodes, and potential pathogenetic mechanisms are discussed.
authors.affiliation: Department of Pediatrics of Medical Microbiology at University of Lübeck. haertel@paedia.ukl.mu-luebeck.de
authors.forename: C
authors.initials: C
authors.lastname: Härtel
authors.forename: A
authors.initials: A
authors.lastname: Herz
authors.forename: S
authors.initials: S
authors.lastname: Vieth
authors.forename: C
authors.initials: C
authors.lastname: Lensing
authors.forename: C
authors.initials: C
authors.lastname: Schultz
mesh_terms: D002675:Child, Preschool; D003937:Diagnosis, Differential; D004232:Diuretics / Q000008:administration & dosage; D005260:Female; D005440:Fluid Therapy; D005665:Furosemide / Q000008:administration & dosage; D005921:Glomerulonephritis / Q000175:diagnosis / Q000628:therapy / Q000821:virology*; D006417:Hematuria / Q000821:virology; D006463:Hemolytic-Uremic Syndrome / Q000175:diagnosis / Q000628:therapy / Q000821:virology*; D006801:Humans; D010322:Parvoviridae Infections / Q000175:diagnosis / Q000628:therapy / Q000821:virology*; D016732:Parvovirus B19, Human / Q000235:genetics / Q000472:pathogenicity*; D016133:Polymerase Chain Reaction; D011507:Proteinuria / Q000821:virology; D014774:Virulence
chemical_list: D004232:Diuretics; D005665:Furosemide