title: Muscular pseudohypertrophy (steatosis) in a bovine fetus.
abstract: Muscular pseudohypertrophy was diagnosed in the cervical musculature of a full-term crossbred Simmental fetus delivered by fetotomy. Only head and cervical regions were submitted for pathologic examination; the rest of the fetal body was reportedly normal. The neck musculature of the fetus was markedly deformed by 23 cm and 18 cm in diameter, firm, spherical masses that consisted of enlarged and pale left splenius and right serratus ventralis cervicis muscle, respectively, covered by intact skin. Additionally, lipomatous masses were present within the cervical vertebral canal, compressing the spinal cord. Microscopically, the prominent muscular enlargement was due to massive adipose and fibrous connective tissue replacement of atrophic muscle. Focal myelodysplasia and astrocytosis affecting the grey matter was detected in the mid-cervical region of the spinal cord, accompanied by degeneration in the ascending and descending tracts of the remaining cord segments. Abnormal spinal cord development as a result of severe spinal cord compression by the lipomatous masses within the spinal canal leading to replacement of muscle by fat and fibrous tissue was considered to be the cause of the muscular malformation in this fetus.
authors.affiliation: Animal Disease Diagnostic Laboratory , School of Veterinary Medicine, Purdue University, West Lafayette, IN 47907, USA. ilangohr@purdue.edu
authors.forename: Ingeborg M
authors.initials: IM
authors.lastname: Langohr
authors.forename: Gregory W
authors.initials: GW
authors.lastname: Stevenson
authors.forename: Beth A
authors.initials: BA
authors.lastname: Valentine
mesh_terms: D000818:Animals; D002417:Cattle; D002418:Cattle Diseases / Q000196:embryology / Q000473:pathology*; D005260:Female; D007315:Insemination, Artificial / Q000662:veterinary; D018482:Muscle, Skeletal / Q000196:embryology* / Q000473:pathology*; D009133:Muscular Atrophy / Q000196:embryology / Q000473:pathology / Q000662:veterinary*; D011247:Pregnancy; D013116:Spinal Cord / Q000196:embryology / Q000473:pathology