Psoriasis--a possible candidate for vaccination.
The clinical association of streptococcal infections and psoriasis is well established. The recent finding that the T cells in psoriasis skin respond to streptococcal peptidoglycan now suggests a pathway for an adaptive immune response to the streptococcal organism. These observations may allow for possible vaccines to be developed for psoriasis.
Fry
Lionel
L
Faculty of Medicine, Imperial College, London W2 1PG, United Kingdom. l.fry@imperial.ac.uk
Baker
Barbara S
BS
Powles
Anne V
AV
D015395:Histocompatibility Antigens Class I / Q000378:metabolism; D006801:Humans; D011565:Psoriasis / Q000235:genetics / Q000276:immunology / Q000473:pathology / Q000628:therapy*; D013290:Streptococcal Infections / Q000150:complications / Q000276:immunology; D014611:Vaccination
D015395:Histocompatibility Antigens Class I