title: Hypertrophic cardiomyopathy complicated by left ventricular apical necrosis and aneurysm in a young man: FDG-PET findings.
abstract: A 29-year old male was transferred to our hospital with an abnormal chest X-ray finding diagnosed as hypertrophic cardiomyopathy with apical necrosis and aneurysm formation. Four years after the initial hospitalization, we confirmed the aneurysm and necrosis using both integrated positron emission tomography (PET) and computed tomography (CT) scanning. The F-18 2-fluoro-2-deoxy-D-glucose (FDG) PET/CT enabled precise localization of the aneurysm, which was found to be composed of semi-lunar calcification of non-metabolic myocardium. A contrast-enhanced CT angiography showed an hour-glass appearance of the left ventricular cavity. The integrated PET/CT fusion scanner is a novel multimodality technology that allows for a comprehensive analysis of the anatomical and functional status of complex heart disease. Based on these findings, long standing mechanical and physiologic abnormalities may have led to chronic ischemia in the hypertrophied myocardium, induced necrosis and calcification at the cardiac apex.
authors.affiliation: Division of Cardiology, Department of Internal Medicine, Yeungnam University Hospital, Daegu, Korea.
authors.forename: Jong-Seon
authors.initials: JS
authors.lastname: Park
authors.forename: Ihn-Ho
authors.initials: IH
authors.lastname: Cho
authors.forename: Dong-Gu
authors.initials: DG
authors.lastname: Shin
authors.forename: Young-Jo
authors.initials: YJ
authors.lastname: Kim
authors.forename: Gu-Ru
authors.initials: GR
authors.lastname: Hong
authors.forename: Bong-Sup
authors.initials: BS
authors.lastname: Shim
mesh_terms: D000328:Adult; D015901:Angiography, Digital Subtraction; D002312:Cardiomyopathy, Hypertrophic / Q000150:complications / Q000175:diagnosis*; D003287:Contrast Media; D019788:Fluorodeoxyglucose F18; D006322:Heart Aneurysm / Q000150:complications / Q000175:diagnosis*; D006352:Heart Ventricles / Q000473:pathology*; D006801:Humans; D008297:Male; D009336:Necrosis / Q000150:complications / Q000175:diagnosis*; D049268:Positron-Emission Tomography; D014057:Tomography, X-Ray Computed
chemical_list: D003287:Contrast Media; D019788:Fluorodeoxyglucose F18