title: Prognostic value of human chorionic gonadotropin changes after methotrexate injection for ectopic pregnancy.
abstract: Because early prediction of clinical outcome (one or more injections or surgery) of methotrexate treatment of ectopic pregnancy could ease the intensity of follow-up and patient compliance required, we studied the relationship between the change in hCG levels after methotrexate injection and outcome in 129 consecutive patients. A 20% decline in hCG levels between days 1 and 4 during methotrexate treatment has a positive predictive value of 97%.
authors.affiliation: Service de Gynécologie Obstétrique, Hôpital La Conception, Marseille, France. aagostini@mail.ap-hm.fr <aagostini@mail.ap-hm.fr>
authors.forename: Aubert
authors.initials: A
authors.lastname: Agostini
authors.forename: Karina
authors.initials: K
authors.lastname: Blanc
authors.forename: Isabelle
authors.initials: I
authors.lastname: Ronda
authors.forename: Fanny
authors.initials: F
authors.lastname: Romain
authors.forename: Mariane
authors.initials: M
authors.lastname: Capelle
authors.forename: Bernard
authors.initials: B
authors.lastname: Blanc
mesh_terms: D000020:Abortifacient Agents, Nonsteroidal / Q000008:administration & dosage; D006063:Chorionic Gonadotropin / Q000097:blood*; D005260:Female; D006801:Humans; D007267:Injections; D008727:Methotrexate / Q000008:administration & dosage*; D011237:Predictive Value of Tests; D011247:Pregnancy; D011258:Pregnancy Tests; D011271:Pregnancy, Ectopic / Q000097:blood / Q000175:diagnosis* / Q000188:drug therapy*; D011379:Prognosis; D012680:Sensitivity and Specificity
chemical_list: D000020:Abortifacient Agents, Nonsteroidal; D006063:Chorionic Gonadotropin; D008727:Methotrexate