[Current status of islet transplantation].
Due to the numerous advances in islet transplantation in the last few years, clinical outcomes following this procedure are continually improving. Novel immunosuppression protocols, improved donor and recipient selection, and careful attention to the process of organ extraction, preservation and islet isolation have contributed to long-term success. The present article reviews the results of clinical islet transplantation and their relationship with the different advances introduced. The use of new islet sources such as living and non-heart-beating donors, as well as recent advances in our knowledge of the mechanisms of rejection and its prevention, are also reviewed.
Balibrea del Castillo
José María
JM
Departamento de Cirugía, Facultad de Medicina, Universidad Complutense de Madrid, Madrid, España. jose_balibrea@yahoo.es
Vara Ameigeiras
Elena
E
Arias-Díaz
Javier
J
García Martín
M Cruz
MC
García-Pérez
Juan Carlos
JC
Balibrea Cantero
José Luis
JL
D006084:Graft Rejection / Q000517:prevention & control; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D016381:Islets of Langerhans Transplantation / Q000379:methods* / Q000592:standards*; D019520:Living Donors; D013030:Spain
D007166:Immunosuppressive Agents