title: Paragangliomas of the head and neck.
abstract: OBJECTIVE
  The purpose of this study was to determine the clinical characteristics of carotid body tumors and to analyze the benefits of different treatment modalities.
  
  
  METHODS
  The clinical records of 13 patients with paragangliomas treated during the period of 1995-2005 were reviewed for age at diagnosis, sex, initial symptoms, duration of symptoms, evidence of secretory function, family history, radiographic studies, pre- and posttreatment cranial nerve deficits, multicentric tumors, angiography, operative procedures and findings, and complications. The diagnoses were established by computerized tomography and magnetic resonance imaging scanning. Angiography was performed on 3 patients with carotid body tumor.
  
  
  RESULTS
  All of the patients were followed up for a duration ranging from 16 months to 9 years. The median follow-up was 5 years. Of all 18 head and neck tumors confirmed in 13 patients, 16 were in the carotid body, 1 in the vagus nerve and 1 in the middle ear cleft. Four patients had multiple paragangliomas, 2 bilateral synchronous and 1 bilateral asynchronous paragangliomas. The remaining patient had 3 asynchronous paragangliomas, i.e. left jugulotympanic, right carotid body and left vagal paraganglioma. All patients underwent successful surgical resection of the tumor after appropriate preoperative investigation.
  
  
  CONCLUSIONS
  This study shows that surgical treatment is acceptably safe and effective in treating these neoplasms.
authors.affiliation: Department of Otolaryngology, Karadeniz Technique University, Trabzon, Turkey.
authors.forename: A Cemal Umit
authors.initials: AC
authors.lastname: Işik
authors.forename: Mehmet
authors.initials: M
authors.lastname: Imamoğlu
authors.forename: Cihangir
authors.initials: C
authors.lastname: Erem
authors.forename: Ahmet
authors.initials: A
authors.lastname: Sari
mesh_terms: D000328:Adult; D015901:Angiography, Digital Subtraction; D005260:Female; D005500:Follow-Up Studies; D006258:Head and Neck Neoplasms / Q000175:diagnosis* / Q000601:surgery*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D010235:Paraganglioma / Q000175:diagnosis* / Q000601:surgery*; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome