title: In vitro characteristics of a bioabsorbable suspension screw and suture system for endoscopic brow lift surgery.
abstract: The time requirement for endoscopic subperiosteal brow lift fixation is as little as 10-14 days. Many types of bioabsorbable fixation have been applied to this procedure, including bioabsorbable suture coupled with a bioabsorbable bone anchor, with excellent outcomes. Typically, the anchor and suture materials differ, each having their own hydrolytic strength loss profile. The dynamic relationship between the instantaneous state of degradation of the bone anchor and the suture components can affect fixation strength and failure mode, a poorly understood phenomenon. We examined the use of 2x5 mm PLLA-PGA (82:18) copolymer screws containing a suture eyelet in the head, paired with one of four types of bioabsorbable suture (2-0 and 3-0 Vicryl and 2-0 and 3-0 PDS-II), in a model system designed to mimic brow lift fixation. Constructs were inserted into a synthetic bone substrate and incubated in pH 7.4 buffer at 37 degrees C for up to 3 weeks, then loaded to failure. Initial failure loads were dependent upon suture size but not suture material, with 2-0 suture constructs (63-70N) failing at twice the load of the 3-0 suture constructs (30-35N). The following 3 week strength retentions were obtained: 40-55% for 2-0 and 3-0 Vicryl suture, 100% for 3-0 PDS-II suture, and 58% for 2-0 PDS-II suture constructs. The predominant failure mode was suture breakage at the knot, with the later intervals utilizing 2-0 PDS-II suture including some screw head failures. This suspension screw, when coupled with an appropriate suture, appears to have suitable mechanical properties for endoscopic brow lift fixation.
authors.affiliation: Department of Bioengineering, University of Illinois at Chicago, Chicago, IL, USA. billsp@uic.edu
authors.forename: William S
authors.initials: WS
authors.lastname: Pietrzak
authors.forename: Barry L
authors.initials: BL
authors.lastname: Eppley
mesh_terms: D020341:Absorbable Implants; D001863:Bone Screws; D004724:Endoscopy; D005546:Forehead / Q000601:surgery*; D019344:Lactic Acid; D008422:Materials Testing; D016687:Polydioxanone; D011098:Polyglactin 910; D011100:Polyglycolic Acid; D000077182:Polylactic Acid-Polyglycolic Acid Copolymer; D011108:Polymers; D019651:Plastic Surgery Procedures / Q000295:instrumentation*; D013314:Stress, Mechanical; D053441:Suture Anchors; D013537:Sutures; D013718:Tensile Strength
chemical_list: D011108:Polymers; D000077182:Polylactic Acid-Polyglycolic Acid Copolymer; D011100:Polyglycolic Acid; D016687:Polydioxanone; D019344:Lactic Acid; D011098:Polyglactin 910