title: Value of computed tomography in the diagnosis of the cause of nontraumatic gastrointestinal tract perforation.
abstract: OBJECTIVE
  To identify computed tomographic features with a high predictive value to differentiate gastroduodenal ulcer perforations from other causes of perforations in patients with a non-traumatic-free pneumoperitoneum.
  
  
  METHODS
  Computed tomographic scans of 81 patients with a non-traumatic-free pneumoperitoneum were reviewed for direct visualization of the perforation site and indirect findings of the perforation, including the presence, amount, and localization of air and ascites in the peritoneal cavity, mural thickness of the gastrointestinal tract, perigastrointestinal fat stranding, intestinal ischemia, fecal peritonitis, abscess, and portomesenteric venous gas.
  
  
  RESULTS
  The perforation site was directly visualized in 16 (41%) of 39 patients with gastroduodenal ulcer perforation and in 5 (12%) of 42 patients with other causes of perforation. The findings with a positive predictive value of more than 90% for gastroduodenal ulcer perforation were the presence of local fluid between the duodenum and the pancreatic head and the combination of local gastroduodenal wall thickening and fat stranding. The presence of abscess in the peritoneal cavity or fecal peritonitis, portomesenteric gas, or bowel ischemia findings had a positive predictive value of 100% for the diagnosis of other perforations.
  
  
  CONCLUSIONS
  Indirect computed tomographic findings are helpful for differentiating gastroduodenal ulcer perforation from other causes of perforations.
authors.affiliation: Department of Radiology, Centre Hospitalier Universitaire Lapeyronie, Montpellier, France.
authors.forename: Olivier
authors.initials: O
authors.lastname: Ghekiere
authors.forename: Alvian
authors.initials: A
authors.lastname: Lesnik
authors.forename: Denis
authors.initials: D
authors.lastname: Hoa
authors.forename: Guillaume
authors.initials: G
authors.lastname: Laffargue
authors.forename: Claire
authors.initials: C
authors.lastname: Uriot
authors.forename: Patrice
authors.initials: P
authors.lastname: Taourel
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003287:Contrast Media / Q000008:administration & dosage; D003937:Diagnosis, Differential; D005260:Female; D041981:Gastrointestinal Tract / Q000000981:diagnostic imaging*; D006801:Humans; D007416:Intestinal Perforation / Q000175:diagnosis*; D008297:Male; D008875:Middle Aged; D010437:Peptic Ulcer / Q000175:diagnosis*; D011027:Pneumoperitoneum / Q000209:etiology; D011237:Predictive Value of Tests; D011856:Radiographic Image Enhancement / Q000379:methods; D015203:Reproducibility of Results; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D036542:Tomography, Spiral Computed / Q000379:methods*
chemical_list: D003287:Contrast Media