title: [Clinical polymorphism of cutaneous leishmaniasis in centre and south of Tunisia].
abstract: The cutaneous leishmaniasis (CL) is an affection which is quite well known in Tunisia. The zoonotic cutaneous leishmaniasis caused by Leishmania major by far the more frequent, is endemo-epidemic in the centre and south of the country. It is characterized by clinical polymorphism. The aim of our study is to precise the different clinical aspects of the CL in our region through a prospective study of 102 cases. The average age was 37.8 years old (from 4 to 78 years old) with a slight female predominance. All of our cases lived or stayed in an endemic zone. Various clinical forms were noted in our series. The ulcerated and crusted form was predominant: 54,9% of the cases, the lupoid form was noted in 15.7% of the cases and the sporotrichoid form was observed in 18.6% of the cases. Other rare forms were noted (papular erysipeloid, verrucous, vegetant, erythematous, ulcerated, necrotic and linear) were noted in 25.5% of the cases. Our series is characterized by the multiplicity of clinical forms. Besides, the classical form (ulcerated and crusted form), other clinical form can be individualised: lupoid, loco regional spreading (sporotrichoid form, satellite papules). Some atypical forms can be found which are due to variation of host immune responses and to the strain of the parasites involved.
authors.affiliation: Service de dermatologie, EPS Hedi-Chaker, 3029 Sfax, Tunisie. masmoudiabd@yahoo.fr
authors.forename: A
authors.initials: A
authors.lastname: Masmoudi
authors.forename: N
authors.initials: N
authors.lastname: Ayadi
authors.forename: S
authors.initials: S
authors.lastname: Boudaya
authors.forename: T J
authors.initials: TJ
authors.lastname: Meziou
authors.forename: M
authors.initials: M
authors.lastname: Mseddi
authors.forename: S
authors.initials: S
authors.lastname: Marrekchi
authors.forename: S
authors.initials: S
authors.lastname: Bouassida
authors.forename: H
authors.initials: H
authors.lastname: Turki
authors.forename: A
authors.initials: A
authors.lastname: Zahaf
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D019353:Endemic Diseases; D005148:Facial Dermatoses / Q000453:epidemiology / Q000276:immunology / Q000469:parasitology / Q000473:pathology; D005260:Female; D006229:Hand Dermatoses / Q000453:epidemiology / Q000276:immunology / Q000469:parasitology / Q000473:pathology; D006801:Humans; D016773:Leishmaniasis, Cutaneous / Q000453:epidemiology / Q000276:immunology / Q000473:pathology*; D008297:Male; D010641:Phenotype; D011446:Prospective Studies; D012424:Rural Population; D012883:Skin Ulcer / Q000453:epidemiology / Q000276:immunology / Q000469:parasitology / Q000473:pathology*; D014416:Tunisia / Q000453:epidemiology