Repairing the myofilaments to heal the heart.
Frazier
Aisha
A
Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Murphy
Anne M
AM
D008841:Actin Cytoskeleton / Q000187:drug effects / Q000378:metabolism*; D000818:Animals; D002118:Calcium / Q000378:metabolism*; D024741:Cardiomyopathy, Hypertrophic, Familial / Q000235:genetics / Q000378:metabolism / Q000473:pathology / Q000503:physiopathology / Q000628:therapy*; D004195:Disease Models, Animal; D018014:Gene Transfer Techniques; D015316:Genetic Therapy / Q000379:methods*; D005838:Genotype; D051379:Mice; D008822:Mice, Transgenic; D009154:Mutation; D009200:Myocardial Contraction / Q000187:drug effects; D009206:Myocardium / Q000378:metabolism* / Q000473:pathology; D010641:Phenotype; D012333:RNA, Messenger / Q000378:metabolism; D011993:Recombinant Fusion Proteins / Q000378:metabolism; D012720:Severity of Illness Index; D014335:Tropomyosin / Q000235:genetics / Q000378:metabolism*
D012333:RNA, Messenger; D011993:Recombinant Fusion Proteins; C490774:Tpm1 protein, mouse; D014335:Tropomyosin; D002118:Calcium