title: Structural and mechanical evaluations of a topology optimized titanium interbody fusion cage fabricated by selective laser melting process.
abstract: A topology optimized lumbar interbody fusion cage was made of Ti-Al6-V4 alloy by the rapid prototyping process of selective laser melting (SLM) to reproduce designed microstructure features. Radiographic characterizations and the mechanical properties were investigated to determine how the structural characteristics of the fabricated cage were reproduced from design characteristics using micro-computed tomography scanning. The mechanical modulus of the designed cage was also measured to compare with tantalum, a widely used porous metal. The designed microstructures can be clearly seen in the micrographs of the micro-CT and scanning electron microscopy examinations, showing the SLM process can reproduce intricate microscopic features from the original designs. No imaging artifacts from micro-CT were found. The average compressive modulus of the tested caged was 2.97+/-0.90 GPa, which is comparable with the reported porous tantalum modulus of 3 GPa and falls between that of cortical bone (15 GPa) and trabecular bone (0.1-0.5 GPa). The new porous Ti-6Al-4V optimal-structure cage fabricated by SLM process gave consistent mechanical properties without artifactual distortion in the imaging modalities and thus it can be a promising alternative as a porous implant for spine fusion.
authors.affiliation: Spine Research Laboratory, Department of Neurosurgery, The University of Michigan, Ann Arbor, Michigan, USA. lincy@umich.edu
authors.forename: Chia-Ying
authors.initials: CY
authors.lastname: Lin
authors.forename: Tobias
authors.initials: T
authors.lastname: Wirtz
authors.forename: Frank
authors.initials: F
authors.lastname: LaMarca
authors.forename: Scott J
authors.initials: SJ
authors.lastname: Hollister
mesh_terms: D000497:Alloys; D001672:Biocompatible Materials / Q000378:metabolism*; D001696:Biomechanical Phenomena; D007834:Lasers; D008422:Materials Testing / Q000379:methods*; D008855:Microscopy, Electron, Scanning; D013123:Spinal Fusion / Q000379:methods*; D014025:Titanium / Q000378:metabolism*; D014057:Tomography, X-Ray Computed
chemical_list: D000497:Alloys; D001672:Biocompatible Materials; D014025:Titanium