Response of HIV-associated proteinuria to antiretroviral therapy in HIV-1-infected children.
HIV-associated nephropathy has been found in children with HIV-1 infection as a late manifestation of this disease; it is associated with nephrotic syndrome with focal segmental glomerulosclerosis and/or mesangial hyperplasia with microcystic tubular dilatation. This is quite rare in children and no cases have been reported from India. Several mechanisms have been hypothesized for the HIV-induced renal damage. We report on two HIV-infected children with HIV-associated proteinuria and dramatic response to antiretroviral therapy.
Shah
Ira
I
Department of Perinatal and Pediatric HIV Clinic, B J Wadia Hospital for Children Parel, Mumbai, India. irashah@pediatriconcall.com
D016263:AIDS-Associated Nephropathy / Q000175:diagnosis / Q000188:drug therapy*; D019380:Anti-HIV Agents / Q000009:adverse effects / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D005260:Female; D015497:HIV-1; D006801:Humans; D008297:Male; D011507:Proteinuria / Q000175:diagnosis* / Q000188:drug therapy
D019380:Anti-HIV Agents