title: Copper-mediated synthesis of tertiary diaryl squaramides.
abstract: Tertiary aryl squaramides were synthesized by using copper catalyzed C-N bond-formation with L-proline as the ligand. Symmetrical diaryl squaramides could be prepared in a one-pot reaction by using excess aryl bromide with varying yields. Unsymmetrical derivatives were prepared by sequential arylation. Yields of the diarylated products were highly sensitive to steric effects.
authors.affiliation: Department of Chemistry and Biochemistry, Queens College and the Graduate Center of the City University of New York, Flushing, New York 11367-1597, USA.
authors.forename: Vijayakumar
authors.initials: V
authors.lastname: Ramalingam
authors.forename: Niala
authors.initials: N
authors.lastname: Bhagirath
authors.forename: Rajeev S
authors.initials: RS
authors.lastname: Muthyala
mesh_terms: D000577:Amides / Q000737:chemistry*; D003300:Copper / Q000737:chemistry*; D008024:Ligands; D015394:Molecular Structure
chemical_list: D000577:Amides; D008024:Ligands; D003300:Copper