Positron emission tomography for predicting malignancy of sinonasal inverted papilloma.
BACKGROUND
Sinonasal inverted papilloma (IP) is an uncommon nasal tumor. It is known for being locally invasive and recurrent, with a high probability of malignant transformation. Accurate initial staging and close surveillance are critical in the management of the disease.


RESULTS
Fluorine-18 fluorodeoxyglucose positron emission tomography (FDG PET) was performed in 5 patients with IP. High FDG uptake (maximum standardized uptake (SUVmax) value >3.0) was observed in all patients, and 2 patients with IP associated with squamous cell carcinoma (SCC) exhibited higher SUVmax values.


CONCLUSIONS
The SUVmax value of a sinonasal tumor can warn the surgeon of the probability of an associated malignancy, even when preoperative biopsy demonstrates a purely benign papilloma.
Shojaku
Hideo
H
Department of Otolaryngology, University of Toyama, Toyama, Japan. hshojaku@med.u-toyama.ac.jp
Fujisaka
Michiro
M
Yasumura
Satsuki
S
Ishida
Masayuki
M
Tsubota
Masahito
M
Nishida
Hiroshi
H
Watanabe
Yukio
Y
Kawano
Masaya
M
Shimizu
Masashi
M
Fukuoka
Jyunya
J
D000368:Aged; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008297:Male; D008875:Middle Aged; D018308:Papilloma, Inverted / Q000000981:diagnostic imaging*; D010255:Paranasal Sinus Neoplasms / Q000000981:diagnostic imaging*; D049268:Positron-Emission Tomography / Q000379:methods*; D011379:Prognosis; D019275:Radiopharmaceuticals; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity
D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18