title: Outbreak of fungemia among neonates caused by Candida haemulonii resistant to amphotericin B, itraconazole, and fluconazole.
abstract: The first outbreak of Candida haemulonii fungemia is described. The seven isolates from the blood of four neonates were identified by DNA sequencing of the ribosomal DNA. They were all resistant to amphotericin B, fluconazole, and itraconazole. This report highlights the emergence of C. haemulonii as an opportunistic pathogen in immunocompromised patients.
authors.affiliation: Department of Microbiology, Faculty of Medicine, Kuwait University, Safat 13110, Kuwait. ziauddin@hsc.edu.kw
authors.forename: Zia U
authors.initials: ZU
authors.lastname: Khan
authors.forename: Noura A
authors.initials: NA
authors.lastname: Al-Sweih
authors.forename: Suhail
authors.initials: S
authors.lastname: Ahmad
authors.forename: Nawal
authors.initials: N
authors.lastname: Al-Kazemi
authors.forename: Seema
authors.initials: S
authors.lastname: Khan
authors.forename: Leena
authors.initials: L
authors.lastname: Joseph
authors.forename: Rachel
authors.initials: R
authors.lastname: Chandy
mesh_terms: D000666:Amphotericin B / Q000494:pharmacology; D000935:Antifungal Agents / Q000494:pharmacology*; D002175:Candida / Q000145:classification / Q000187:drug effects*; D002177:Candidiasis / Q000453:epidemiology / Q000382:microbiology; D004196:Disease Outbreaks; D025141:Drug Resistance, Fungal; D005260:Female; D015725:Fluconazole / Q000494:pharmacology; D016469:Fungemia / Q000453:epidemiology* / Q000382:microbiology; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D007235:Infant, Premature, Diseases / Q000453:epidemiology* / Q000382:microbiology; D017964:Itraconazole / Q000494:pharmacology; D008297:Male; D008826:Microbial Sensitivity Tests; D008969:Molecular Sequence Data; D017422:Sequence Analysis, DNA
chemical_list: D000935:Antifungal Agents; D017964:Itraconazole; D000666:Amphotericin B; D015725:Fluconazole