title: Primary spindle cell sarcoma of the vagina treated with neoadjuvant radiation and pelvic exenteration.
abstract: OBJECTIVE
  Malignant neoplasms of the vagina are rare gynecologic tumors. Primary vaginal sarcomas are even more unusual lesions, representing fewer than 2% of malignant vaginal lesions.
  
  
  METHODS
  We present a case of a primary vaginal spindle cell sarcoma, treated with neoadjuvant radiation followed by total pelvic exenteration. The patient remains without evidence of disease 2 years after surgery.
  
  
  CONCLUSIONS
  The mainstay of treatment of vaginal sarcomas is surgical. Neoadjuvant radiation treatment may decrease surgical morbidity and lead to long-term cure.
authors.affiliation: Department of Obstetrics and Gynecology, SUNY Downstate, Brooklyn, NY 11203, USA. sarah.temkin@gmail.com
authors.forename: Sarah Madhu
authors.initials: SM
authors.lastname: Temkin
authors.forename: Mira
authors.initials: M
authors.lastname: Hellmann
authors.forename: Yi-Chun
authors.initials: YC
authors.lastname: Lee
authors.forename: Ovadia
authors.initials: O
authors.lastname: Abulafia
mesh_terms: D005260:Female; D006470:Hemorrhage / Q000209:etiology* / Q000532:radiotherapy / Q000601:surgery; D006801:Humans; D008875:Middle Aged; D020360:Neoadjuvant Therapy / Q000379:methods*; D010385:Pelvic Exenteration; D018714:Radiotherapy, Adjuvant; D012509:Sarcoma / Q000150:complications / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery*; D016896:Treatment Outcome; D014625:Vaginal Neoplasms / Q000150:complications / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery*