Anti-tumour effects of the sesquiterpene Lactone parthenin.
The anti-tumour effects of the sesquiterpene lactone, parthenin was studied both in vivo and in vitro. Parthenin showed marked cytotoxic activity to P815 mastocytoma, L1210 leukemia, and M-1 rhabdomyosarcoma cells in vitro. In vivo studies showed intraperitoneal drug administration could either cure mice or increase their survival time after intraperitoneal of subcutaneous injection with tumour cells.
Mew
D
D
Department of Microbiology, University of British Columbia Vancouver, British Columbia, Canada.
Balza
F
F
Towers
G H
GH
Levy
J G
JG