title: Preliminary evidence of a sensitive period for olfactory learning by human newborns.
abstract: OBJECTIVE
  To test the hypothesis that a brief window of time immediately after delivery may be a particularly sensitive period for olfactory learning by human neonates.
  
  
  METHODS
  Fifty-five vaginally delivered newborns were exposed to an odorant for 30 min beginning 4-37 min after birth (Early exposure) or 12-h post-partum (Late exposure). Several days later, newborns' head orientation responses to the exposure odour versus an unfamiliar odour or an odourless control stimulus were tested.
  
  
  RESULTS
  Infants in the Early exposure group spent significantly more time oriented towards the familiar scent rather than a novel odour (Z = 2.869; n = 28; p < 0.01), or an odourless stimulus (Z = 2.550; n = 28; p < 0.01). Infants in the Late exposure condition did not respond differentially to the exposure odour versus a novel odour (Z = 1.105; n = 27, p = 0.27), and spent more time oriented towards an odourless stimulus than to the exposure odour (Z = 2.042; n = 27, p < 0.05).
  
  
  CONCLUSIONS
  Infants in the Early exposure group, but not in the Late exposure group, became familiar with the exposure odour and retained a memory trace of it during the test trials.
authors.affiliation: Department of Paediatrics, University of Tartu, Tartu, Estonia. olga.romantshik@kliinikum.ee
authors.forename: O
authors.initials: O
authors.lastname: Romantshik
authors.forename: R H
authors.initials: RH
authors.lastname: Porter
authors.forename: V
authors.initials: V
authors.lastname: Tillmann
authors.forename: H
authors.initials: H
authors.lastname: Varendi
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D007231:Infant, Newborn / Q000502:physiology*; D007858:Learning; D008297:Male; D009812:Odorants; D012903:Smell / Q000502:physiology*