Lack of an association between Helicobacter infection and autoimmune hepatitis in children.
An association between Helicobacter infection and autoimmune hepatitis (AIH) in children was investigated. The prevalence of antibodies to H. pylori did not differ between the AIH and the control group, (22% versus 14%), and antibodies to non-gastric Helicobacter were not detected in either group. H. pylori DNA was found in two AIH liver tissues, but Helicobacter was not cultured from any sample.
Dzierzanowska-Fangrat
Katarzyna
K
Department of Clinical Microbiology and Immunology, Children's Memorial Health Institute, Warsaw, Poland. fangrat@supermedia.pl
Nilsson
Ingrid
I
Wozniak
Małgorzata
M
Jozwiak
Paulina
P
Rozynek
Elzbieta
E
Woynarowski
Marek
M
Socha
Jerzy
J
Ljungh
Asa
A
Wadström
Torkel
T
D000293:Adolescent; D000907:Antibodies, Bacterial / Q000032:analysis; D001706:Biopsy; D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D005260:Female; D016481:Helicobacter Infections / Q000276:immunology*; D016480:Helicobacter pylori / Q000235:genetics / Q000276:immunology* / Q000472:pathogenicity; D019693:Hepatitis, Autoimmune / Q000276:immunology* / Q000382:microbiology*; D006801:Humans; D008297:Male
D000907:Antibodies, Bacterial