title: The detection of myocardial ischemia in end-stage renal disease.
abstract: The outcome of acute coronary syndromes is usually poor in patients with end-stage renal disease (ESRD), and the early detection of myocardial ischemia is therefore essential in this group. However, the diagnosis of ischemina is often problematic in patients with ESRD, as cardiac symptoms and electrocardiography are not reliable predictors in this context. Silent ischemia is common and resting ECG is often abnormal in patients with ESRD. Therefore, alternatives to these predictors have been sought, and this review explores the role of myocardial perfusion imaging, dobutamine stress echocardiography and biochemical markers for use in the diagnosis of ischemia and risk stratification in patients with ESRD.
authors.affiliation: Ealing Hospital NHS Trust, Uxbridge Road. Southal, Middlesex UB1 3HW UK. rajdoc.sharma@tiscali.co.uk
authors.forename: Rajan
authors.initials: R
authors.lastname: Sharma
authors.forename: Denis
authors.initials: D
authors.lastname: Pellerin
authors.forename: Stephen J D
authors.initials: SJ
authors.lastname: Brecker
mesh_terms: D015415:Biomarkers / Q000097:blood; D025401:Echocardiography, Stress / Q000379:methods; D006801:Humans; D007676:Kidney Failure, Chronic / Q000150:complications*; D017202:Myocardial Ischemia / Q000150:complications / Q000175:diagnosis* / Q000503:physiopathology; D011877:Radionuclide Imaging / Q000379:methods
chemical_list: D015415:Biomarkers