Primary splenic marginal zone lymphoma with florid granulomatous reaction--a case report and review of literature.
Splenic marginal zone lymphomas (SMZL) constitute about 20% of primary splenic NHLs. We report a case of primary SMZL with a florid granulomatous reaction which obscured the underlying lymphoma. Although granulomas have been described in splenic non-Hodgkin lymphoma, it can be extensive and mask the underlying lymphoma. A careful search for the cytoarchitectural features of SMZL is warranted in such a case.
Manipadam
M T
MT
Department of General Pathology, Christian Medical College, Vellore 632004, Tamil Nadu, India. mtm2005@cmcvellore.ac.in
Viswabandya
A
A
Srivastava
A
A
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000744:Anemia, Hemolytic, Autoimmune / Q000150:complications / Q000188:drug therapy; D004791:Enzyme Inhibitors / Q000627:therapeutic use; D006099:Granuloma / Q000473:pathology*; D006801:Humans; D007150:Immunohistochemistry; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008228:Lymphoma, Non-Hodgkin / Q000473:pathology* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D009173:Mycophenolic Acid / Q000627:therapeutic use; D013156:Splenectomy; D013160:Splenic Neoplasms / Q000473:pathology* / Q000601:surgery
D000305:Adrenal Cortex Hormones; D004791:Enzyme Inhibitors; D007166:Immunosuppressive Agents; D009173:Mycophenolic Acid