title: [Contribution of liver biopsy in intensive care unit. (180/2004)].
abstract: OBJECTIVE
  Our aim was to evaluate the indications and contribution of liver biopsy (LB) in intensive care (ICU) and to compare them to those of LB in gastroenterology.
  
  
  METHODS
  We included retrospectively 37 successive LB achieved in ICU and 38 successive LB achieved in gastroenterology. All data were reviewed by three intensivists and three gastroenterologists to determine the contribution of the LB.
  
  
  RESULTS
  The indications of LB were different in the two units. The most frequent indications were cirrhosis (36.8%), isolated biological hepatic disruptions (26.3%) and histological classification of viral hepatitis (18.4%) in gastroenterology and isolated biological hepatic disruptions (48.6%), hepatopathy during pregnancy (27%) and fever of unknown origin (10.8%) in intensive care unit. According to the six reviewers, LB was enough contributive in the two units, (78.4% in ICU and 71.1% in gastroenterology -p=0.46-). It allowed to eliminate, to confirm, or to change a diagnosis in more than 70% of cases and allowed to modify the course of therapy in 21.6% of cases in ICU and in 26.3% of cases in gastroenterology (p-0.6).
  
  
  CONCLUSIONS
  The LB is a feasible technique in ICU and can be as contributive as it is in gastroenterology.
authors.affiliation: Service de Réanimation Médicale, CHU Habib Bourguiba, Sfax, Tunisie.
authors.forename: Hatem
authors.initials: H
authors.lastname: Kallel
authors.forename: Nadia Khlaf
authors.initials: NK
authors.lastname: Bouaziz
authors.forename: Anis
authors.initials: A
authors.lastname: Chaari
authors.forename: Mabrouk
authors.initials: M
authors.lastname: Bahloul
authors.forename: Mohamed Salah
authors.initials: MS
authors.lastname: Krichène
authors.forename: Mounir
authors.initials: M
authors.lastname: Bouaziz
mesh_terms: D000328:Adult; D000368:Aged; D001707:Biopsy, Needle; D002648:Child; D003627:Data Interpretation, Statistical; D005240:Feasibility Studies; D005260:Female; D005335:Fever of Unknown Origin / Q000473:pathology; D005762:Gastroenterology; D006525:Hepatitis, Viral, Human / Q000473:pathology; D006748:Hospital Departments; D006801:Humans; D007362:Intensive Care Units; D008099:Liver / Q000473:pathology*; D008103:Liver Cirrhosis / Q000473:pathology; D008107:Liver Diseases / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D011247:Pregnancy; D011248:Pregnancy Complications / Q000473:pathology; D012189:Retrospective Studies