Prime time for polycystic kidney disease: does one shot of roscovitine bring the cure?
Kuehn
E Wolfgang
EW
Renal Division, University Hospital Freiburg, Hugstetter Strasse 55, 79104 Freiburg, Germany.
Walz
Gerd
G
D000818:Animals; D065092:Antidiuretic Hormone Receptor Antagonists; D002986:Clinical Trials as Topic; D004195:Disease Models, Animal; D005799:Genes, Dominant; D006801:Humans; D051379:Mice; D008954:Models, Biological; D007690:Polycystic Kidney Diseases / Q000188:drug therapy* / Q000235:genetics; D047428:Protein Kinase Inhibitors / Q000627:therapeutic use; D011494:Protein Kinases / Q000378:metabolism; D011687:Purines / Q000494:pharmacology*; D000077546:Roscovitine; D058570:TOR Serine-Threonine Kinases
D065092:Antidiuretic Hormone Receptor Antagonists; D047428:Protein Kinase Inhibitors; D011687:Purines; D000077546:Roscovitine; D011494:Protein Kinases; C546842:MTOR protein, human; C546843:mTOR protein, mouse; D058570:TOR Serine-Threonine Kinases