Bio-guided isolation of antioxidants from the stems of Dendrobium aurantiacum var. denneanum.
Bio-guided fractionation of the stems of Dendrobium aurantiacum var. denneanum using a 1,1-diphenyl-2-picryl-hydrazyl (DPPH) radical scavenging assay, led to the isolation of three 2-glucosyloxycinnamic acid derivates, namely, cis-melilotoside, trans-melilotoside and dihydromelilotoside, respectively. Their structures were elucidated through the analysis of uni- and bi-dimensional NMR, UV, IR and MS data. All these three compounds were first reported from the genus Dendrobium and exhibited potent antioxidant activities.
Yang
Li
L
Key Laboratory of Standardization of Chinese Medicines of Ministry of Education, Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, 201203 Shanghai, PR China.
Han
Haofeng
H
Nakamura
Norio
N
Hattori
Masao
M
Wang
Zhengtao
Z
Xu
Luoshan
L
D000975:Antioxidants / Q000737:chemistry*; D001713:Biphenyl Compounds; D031667:Dendrobium; D006801:Humans; D008517:Phytotherapy; D010851:Picrates / Q000737:chemistry; D010936:Plant Extracts / Q000737:chemistry*; D018547:Plant Stems; D013329:Structure-Activity Relationship
D000975:Antioxidants; D001713:Biphenyl Compounds; D010851:Picrates; D010936:Plant Extracts; C004931:1,1-diphenyl-2-picrylhydrazyl