Scoparone inhibits ultraviolet radiation-induced lipid peroxidation.
Antioxidant capabilities of scoparone, the component of Artemisia scoparia and other medicinal plants, against lipid peroxidation induced by ultraviolet radiation or Fenton reaction have been analyzed. Lipid peroxidation was monitored by measuring the absorption spectra of the conjugated dienes and quantified by the Klein oxidation index. Obtained results imply that scoparone is a very efficient inhibitor of ultraviolet radiation-induced lipid peroxidation and damage.
Sourivong
Paul
P
Department of Radiation Oncology, Willis-Knighton Cancer Center, 2600 Kings Highway, Shreveport, Louisiana 71103, USA.
Schronerová
Kristina
K
Babincová
Melánia
M
D019306:Artemisia / Q000737:chemistry; D003374:Coumarins / Q000302:isolation & purification / Q000494:pharmacology*; D006861:Hydrogen Peroxide; D007501:Iron; D015227:Lipid Peroxidation / Q000187:drug effects* / Q000528:radiation effects*; D010713:Phosphatidylcholines / Q000737:chemistry / Q000528:radiation effects; D014466:Ultraviolet Rays
D003374:Coumarins; C045076:Fenton's reagent; D010713:Phosphatidylcholines; D006861:Hydrogen Peroxide; D007501:Iron; C018145:scoparone