title: YhdJ, a nonessential CcrM-like DNA methyltransferase of Escherichia coli and Salmonella enterica.
abstract: The Caulobacter crescentus DNA adenine methyltransferase CcrM and its homologs in the alpha-Proteobacteria are essential for viability. CcrM is 34% identical to the yhdJ gene products of Escherichia coli and Salmonella enterica. This study provides evidence that the E. coli yhdJ gene encodes a DNA adenine methyltransferase. In contrast to an earlier report, however, we show that yhdJ is not an essential gene in either E. coli or S. enterica.
authors.affiliation: Department of Biology, IIU, Area 12, University of York, P.O. Box 373, York Y010 5YW, England.
authors.forename: Sarah E
authors.initials: SE
authors.lastname: Broadbent
authors.forename: Roberto
authors.initials: R
authors.lastname: Balbontin
authors.forename: Josep
authors.initials: J
authors.lastname: Casadesus
authors.forename: Martin G
authors.initials: MG
authors.lastname: Marinus
authors.forename: Marjan
authors.initials: M
authors.lastname: van der Woude
mesh_terms: D001426:Bacterial Proteins / Q000235:genetics / Q000378:metabolism; D001483:Base Sequence; D001665:Binding Sites / Q000235:genetics; D020134:Catalytic Domain / Q000235:genetics; D019175:DNA Methylation; D015254:DNA Modification Methylases / Q000235:genetics / Q000378:metabolism*; D015252:Deoxyribonucleases, Type II Site-Specific / Q000235:genetics / Q000378:metabolism; D004926:Escherichia coli / Q000201:enzymology* / Q000235:genetics; D029968:Escherichia coli Proteins / Q000235:genetics / Q000378:metabolism*; D010957:Plasmids / Q000235:genetics / Q000378:metabolism; D019779:Salmonella enterica / Q000201:enzymology* / Q000235:genetics; D015265:Site-Specific DNA-Methyltransferase (Adenine-Specific) / Q000235:genetics / Q000378:metabolism*
chemical_list: D001426:Bacterial Proteins; D029968:Escherichia coli Proteins; D015254:DNA Modification Methylases; D015265:Site-Specific DNA-Methyltransferase (Adenine-Specific); C522508:YhdJ protein, E coli; C048503:ATGCAT-specific type II deoxyribonucleases; D015252:Deoxyribonucleases, Type II Site-Specific