[Blood plasma proteins following long-duration space flight].
Protein composition of blood plasma was an object of investigation in 29 Russian cosmonauts flown on the MIR station from 125 to 366 days. Protein fractions were analyzed using acetate cellulose electrophoresis. Concentration of total protein was determined with the help of the biuret reaction on an automated analyzer. On the second day post flight, mean concentration of total protein and percentage of the protein fractions were equal to baseline values. In the interval between days 7 and 14 post flight, total protein was statistically reduced, alphal- N alpha2-globulins increased and y-globulin reduced, whereas albumin and beta-globulins were unchanged in the average. These results may point to development of an acute reaction in the early period of readaptation to the return from long-duration space flight.
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D000222:Adaptation, Physiological / Q000502:physiology*; D000510:Alpha-Globulins / Q000378:metabolism*; D001609:Beta-Globulins / Q000378:metabolism*; D015415:Biomarkers / Q000097:blood; D004588:Electrophoresis, Cellulose Acetate; D005500:Follow-Up Studies; D005914:Globins / Q000378:metabolism*; D006801:Humans; D011379:Prognosis; D012709:Serum Albumin / Q000378:metabolism; D013026:Space Flight; D013997:Time Factors; D014893:Weightlessness; D005719:gamma-Globulins / Q000378:metabolism*
D000510:Alpha-Globulins; D001609:Beta-Globulins; D015415:Biomarkers; D012709:Serum Albumin; D005719:gamma-Globulins; D005914:Globins