title: Formation of a reliable capsular flap in a rat model.
abstract: Prefabrication can be used to produce capsular flaps; other researchers have confirmed the feasibility of such flaps. Before the possibilities of capsular flaps can be explored, a reliable method to create these flaps has to be established first.
  
  
  METHODS
  To produce capsular flaps in a rat model, the femoral vascular bundle was sandwiched between two silicone sheets. Three different methods were used and described. The capsule that formed between the two silicone sheets receives its main blood supply from that vascular pedicle. In this way pedicled capsular flaps were created. These flaps were used as a carrier for a skin graft, thus pre-laminating them, to test their ability for reconstructive surgery. The results of the three different methods of creating capsular flaps in a rat model were described and their results were evaluated. Especially the amount of capsule formation and the viability of the skin grafts was observed and compared. The feasibility of pre-laminated capsular flaps is confirmed and the most reliable method of creating them is described.
authors.affiliation: Department of Plastic Surgery, Radboud University Nijmegen Medical Center, University of Nijmegen, Reinier Postlaan 4, PO Box 9101, Nijmegen 6500 HB, The Netherlands. schuringa@nvpc.nl
authors.forename: M C
authors.initials: MC
authors.lastname: Schuringa
authors.forename: E H M
authors.initials: EH
authors.lastname: Hartman
authors.forename: P Q
authors.initials: PQ
authors.lastname: Ruhé
authors.forename: J A
authors.initials: JA
authors.lastname: Jansen
authors.forename: P H M
authors.initials: PH
authors.lastname: Spauwen
mesh_terms: D000818:Animals; D005263:Femoral Artery / Q000601:surgery; D005268:Femoral Vein / Q000601:surgery; D023421:Models, Animal; D051381:Rats; D017208:Rats, Wistar; D012828:Silicones; D016038:Skin Transplantation; D013524:Surgical Flaps / Q000473:pathology; D015626:Tissue Expansion
chemical_list: D012828:Silicones