Justicisaponin-I, a new triterpenoid saponin from Justicia simplex.
A new triterpenoid saponin, named justicisaponin-I, has been isolated from Justicia simplex D. Don. (Acanthaceae). It has been assigned oleanolic acid-3-O-beta-D-glucopyranosyl-4'-O-ferulate structure (1) on the basis of chemical transformation and comprehensive spectral evidence. Justicisaponin-I has produced significant sperm acrosomal membrane stabilizing action and may prove to be a potent antifertility agent.
Ghosal
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Department of Pharmaceutics, Banaras Hindu University, Varanasi-5.
Srivastava
A K
AK
Srivastava
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RS
Chattopadhyay
S
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Maitra
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M