title: Cultivation of Tripterygium wilfordii Tissue Cultures for the Production of the Cytotoxic Diterpene Tripdiolide.
abstract: The production of the cytotoxic agent tripdiolide employing plant tissue cultures of TRIPTERYGIUM WILFORDII is demonstrated. Detailed investigations of a developed cell line of T. WILFORDII in terms of tripdiolide production versus variations in growth conditions, for example media composition, are presented. Also the age and size of the inoculum and the incubation period with respect to tripdiolide formation are evaluated.
authors.affiliation: Department of Chemistry, University of British Columbia, Vancouver, Canada.
authors.forename: J P
authors.initials: JP
authors.lastname: Kutney
authors.forename: L S
authors.initials: LS
authors.lastname: Choi
authors.forename: R
authors.initials: R
authors.lastname: Duffin
authors.forename: G
authors.initials: G
authors.lastname: Hewitt
authors.forename: N
authors.initials: N
authors.lastname: Kawamura
authors.forename: T
authors.initials: T
authors.lastname: Kurihara
authors.forename: P
authors.initials: P
authors.lastname: Salisbury
authors.forename: R
authors.initials: R
authors.lastname: Sindelar
authors.forename: K L
authors.initials: KL
authors.lastname: Stuart
authors.forename: P M
authors.initials: PM
authors.lastname: Townsley
authors.forename: W T
authors.initials: WT
authors.lastname: Chalmers
authors.forename: F
authors.initials: F
authors.lastname: Webster
authors.forename: G G
authors.initials: GG
authors.lastname: Jacoli