title: Enabling technologies: fermentation and downstream processing.
abstract: Efficient parallel tools for bioprocess design, consequent application of the concepts for metabolic process analysis as well as innovative downstream processing techniques are enabling technologies for new industrial bioprocesses from an engineering point of view. Basic principles, state-of-the-art techniques and cutting-edge technologies are briefly reviewed. Emphasis is on parallel bioreactors for bioprocess design, biochemical systems characterization and metabolic control analysis, as well as on preparative chromatography, affinity filtration and protein crystallization on a process scale.
authors.affiliation: Lehrsthul für Bioverfahrenstechnik, Technischen Universität München, Boltzmannstr. 15, 85748 Garching, Germany. d.weuster-botz@lrz.tum.de
authors.forename: Dirk
authors.initials: D
authors.lastname: Weuster-Botz
authors.forename: Dariusch
authors.initials: D
authors.lastname: Hekmat
authors.forename: Robert
authors.initials: R
authors.lastname: Puskeiler
authors.forename: Ezequiel
authors.initials: E
authors.lastname: Franco-Lara
mesh_terms: D019149:Bioreactors; D001709:Biotechnology / Q000295:instrumentation / Q000379:methods*; D002845:Chromatography; D005285:Fermentation