title: [Early stage pulmonary alveolar proteinosis detected by chest CT scan in a medical examination].
abstract: We report a case of pulmonary proteinosis detected at an early stage and followed up on chest CT. A 49-year-old man underwent detailed examinations because of abnormal shadows on chest CT taken on a routine medical examination. The chest CT revealed almost symmetrical ground glass opacities (GGOs) in both lungs with thickened alveolar septa. We could not make a definitive diagnosis even with bronchoalveolar lavage and transbronchial lung biopsy, but after about half a year, the GGOs increased. VATS-biopsy demonstrated alveoli filled with PAS-positive granular materials, and we made a diagnosis of pulmonary alveolar proteinosis. This case was found at an early stage and we were then able to follow up the disease.
authors.affiliation: The Division of Respiratory Medicine, Kanazawa Municipal Hospital.
authors.forename: Hazuki
authors.initials: H
authors.lastname: Takato
authors.forename: Yasuto
authors.initials: Y
authors.lastname: Nakatsumi
authors.forename: Kanako
authors.initials: K
authors.lastname: Inuzuka
authors.forename: Toshio
authors.initials: T
authors.lastname: Abe
authors.forename: Masahide
authors.initials: M
authors.lastname: Yasui
authors.forename: Yukari
authors.initials: Y
authors.lastname: Ichikawa
authors.forename: Tomoyuki
authors.initials: T
authors.lastname: Araya
authors.forename: Masaki
authors.initials: M
authors.lastname: Fujimura
mesh_terms: D001706:Biopsy; D006801:Humans; D008297:Male; D008875:Middle Aged; D009098:Multiphasic Screening; D011649:Pulmonary Alveolar Proteinosis / Q000000981:diagnostic imaging* / Q000473:pathology; D011650:Pulmonary Alveoli / Q000473:pathology*; D013902:Radiography, Thoracic; D020775:Thoracic Surgery, Video-Assisted; D014057:Tomography, X-Ray Computed