title: Fertility-sparing radical abdominal trachelectomy for clear cell adenocarcinoma of the upper vagina: a case report.
abstract: BACKGROUND
  Clear cell adenocarcinoma (CCA) of the vagina is traditionally treated with radical surgical resection with tailored postoperative radiation when indicated. Due to a bimodal distribution, women of reproductive age are frequently affected and could benefit from radical trachelectomy to preserve fertility.
  
  
  METHODS
  A 22 year old female was diagnosed with clinical stage I vaginal clear cell adenocarcinoma in the left fornix abutting the cervix. The patient desired future fertility; therefore, she underwent radical abdominal trachelectomy and upper vaginectomy. Twenty-eight months after initial surgery, she has no evidence of recurrence with regular menstrual cycles.
  
  
  CONCLUSIONS
  For patients with CCA of the upper vagina, where removal of the cervix is necessary, a radical trachelectomy with upper vaginectomy should be considered to conserve fertility.
authors.affiliation: Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, University of Alabama at Birmingham, Birmingham, AL 35249-7333, USA. kellie.matthews@obgyn.uab.edu
authors.forename: Kellie S
authors.initials: KS
authors.lastname: Matthews
authors.forename: T Michael
authors.initials: TM
authors.lastname: Numnum
authors.forename: Michael G
authors.initials: MG
authors.lastname: Conner
authors.forename: Mack
authors.initials: M
authors.lastname: Barnes
mesh_terms: D018262:Adenocarcinoma, Clear Cell / Q000473:pathology / Q000601:surgery*; D000328:Adult; D005260:Female; D005298:Fertility; D013509:Gynecologic Surgical Procedures / Q000379:methods; D006801:Humans; D009367:Neoplasm Staging; D014625:Vaginal Neoplasms / Q000473:pathology / Q000601:surgery*