Transient ischaemic attacks and minor strokes (analyses and clinically significant comparisons).
The transient ischaemic attacks (TIA) and minor strokes are independent predictors of disabling strokes with a high medical and social value.


OBJECTIVE
Analysis and comparison of the data from the clinical monitoring of TIA and minor stroke patients in correlation with the different duration of the transient neurological deficit.


METHODS
234 patients were monitored clinically in the Clinic of Cerebrovascular Diseases, University Hospital "St. George"-Plovdiv between 2002 and 2004. Clinical data were collected for 79 patients who met the clinical criteria for TIA and 155 patients who met the clinical criteria for minor stroke. Our protocol included medical history, cardiac and neurological examinations, assessment of cerebrovascular risk factors and laboratory tests. The instrumental assessment included CT scan, MRI and Doppler examination. The data were processed using descriptive statistics, non-parametric methods and charts.


RESULTS
The comparative analysis between the TIA and minor stroke patients shows a significant difference only in the number of registered conductive disturbances, which are more frequent in the TIA patients. In the TIA group the significantly more frequent features are acute onset of the neurological deficit, significantly more frequent normal CT scan images or lacunar infarctions findings. In the minor stroke group the significantly more frequent features are the subacute onset, more frequent CT findings of vascular encephalopathy or CT scans revealing one large ischaemic zone.


CONCLUSIONS
The differences may be explained with the dominant pathogenetic mechanisms in each of the conditions: microembolisation of extracranial vascular origin in TIA and local thrombosis or cardioembolisation in minor stroke. Previous vascular damage in minor stroke patients is more evident.
Atanassova
Penka A
PA
Department of Neurology, Medical University, Plovdiv, Bulgaria.
Semerdjieva
Maria A
MA
Naydenov
Valcho I
VI
Dzhurkova
Albena G
AG
Traykova
Nikoleta I
NI
Chalakova
Nedka T
NT
D003937:Diagnosis, Differential; D003952:Diagnostic Imaging; D005260:Female; D006801:Humans; D002546:Ischemic Attack, Transient / Q000145:classification* / Q000175:diagnosis; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D018709:Statistics, Nonparametric; D020521:Stroke / Q000145:classification* / Q000175:diagnosis