Fine needle aspiration of pulmonary adiaspiromycosis: a case report.
BACKGROUND
Pulmonary adiaspiromycosis is a common disease of many species of wild rodents and occasionally of humans, caused by the inhalation of spores of the fungus Chrysosporium parvum var crescens (Emmonsia crescens).


METHODS
A 74-year-old female with pulmonary adiaspiromycosis was diagnosed by radiologically guided lung fine needle aspiration (FNA). The specimen showed intracellular and extracellular 100-300 microm conidia with a distinct thick, trilaminar wall, which was positive for Gomori-methenamine silver and periodic acid-Schiff stain. The background consisted of a granulomatous process.


CONCLUSIONS
FNA is an effective method of diagnosing pulmonary adiaspiromycosis, and pathologists need to be aware of the characteristic features of this unusual opportunistic fungal infection.
Sun
Yanyu
Y
Division of Cytopathology, Department of Pathology, Long Island Jewish Medical Center, Long Island Campus for Albert Einstein College of Medicine, New Hyde Park, New York 11040, USA.
Bhuiya
Tawfiqul
T
Wasil
Tarun
T
Macias
Antonio
A
Wasserman
Patricia G
PG
D000368:Aged; D044963:Biopsy, Fine-Needle; D002912:Chrysosporium / Q000166:cytology; D003937:Diagnosis, Differential; D005260:Female; D015726:Giant Cells / Q000473:pathology; D006644:Histiocytes / Q000473:pathology; D006801:Humans; D008168:Lung / Q000000981:diagnostic imaging / Q000382:microbiology / Q000473:pathology; D008172:Lung Diseases, Fungal / Q000382:microbiology* / Q000473:pathology* / Q000503:physiopathology; D009181:Mycoses / Q000382:microbiology* / Q000473:pathology* / Q000503:physiopathology; D011237:Predictive Value of Tests; D013194:Staining and Labeling / Q000379:methods; D014057:Tomography, X-Ray Computed