Development of malaria blood-stage vaccines: learning from mosquitoes.
If current methods of vaccine development for malaria continue to result in vaccines with only relatively limited degrees of protection, what is the alternative? Here, a totally different approach to blood-stage vaccine research is suggested, focusing on malarial immunity as it develops in macaque monkeys, but using methodology already well established in mosquito research.
Butcher
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GA
Division of Cell and Molecular Biology, Imperial College London, Sir Alexander Fleming Building, London SW7 2AZ, UK. geoffrey.butcher@virgin.net
D000818:Animals; D006801:Humans; D008018:Life Cycle Stages; D008251:Macaca; D008288:Malaria / Q000517:prevention & control*; D017780:Malaria Vaccines
D017780:Malaria Vaccines