Von Willebrand disease presenting as recurrent hemorrhage after transvaginal oocyte retrieval.
A 34-year-old nulligravid woman experienced hemorrhage after each of 2 oocyte retrievals. Initial coagulopathy screening was negative. Treatments used during in vitro fertilization likely interfered with assay performance. Reevaluation remote from medications confirmed the diagnosis of von Willebrand disease. Treatments used during in vitro fertilization may increase bleeding risk and confound coagulopathy evaluation.
Moayeri
Sharon E
SE
Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology and Infertility, Stanford Hospital, Stanford, CA, USA.
Coutre
Steven E
SE
Ramirez
Edward J
EJ
Westphal
Lynn M
LM
D000328:Adult; D003937:Diagnosis, Differential; D005260:Female; D005307:Fertilization in Vitro / Q000009:adverse effects* / Q000379:methods; D005500:Follow-Up Studies; D006801:Humans; D015907:Hysteroscopy / Q000379:methods; D007247:Infertility, Female / Q000150:complications* / Q000175:diagnosis / Q000628:therapy*; D010062:Ovulation Induction / Q000009:adverse effects* / Q000379:methods; D012008:Recurrence; D018570:Risk Assessment; D012720:Severity of Illness Index; D014592:Uterine Hemorrhage / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D014842:von Willebrand Diseases / Q000150:complications* / Q000175:diagnosis* / Q000628:therapy; D014841:von Willebrand Factor / Q000032:analysis
D014841:von Willebrand Factor