Spontaneous complete remission of a non-small cell lung cancer associated with anti-Hu antibody syndrome.
Anti-Hu antibodies are directed against lung cancer cell antigens. The anti-tumor effect of anti-Hu antibodies has been suggested by several studies demonstrating that patients presenting with anti-Hu antibodies have a longer survival. In this case report, we suggest that the immunology of HuAb paraneplastic syndrome by itself could induce tumor response.
Pujol
Jean-Louis
JL
Hôpital Universitaire Arnaud de Villeneuve, Montpellier, France. jl-pujol@chu-montpellier.fr
Godard
Anne-Laure
AL
Jacot
William
W
Labauge
Pierre
P
D000368:Aged; D000951:Antigens, Neoplasm / Q000276:immunology*; D001323:Autoantibodies / Q000276:immunology*; D002289:Carcinoma, Non-Small-Cell Lung / Q000276:immunology; D002294:Carcinoma, Squamous Cell / Q000276:immunology*; D051959:ELAV Proteins / Q000276:immunology*; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000276:immunology*; D009365:Neoplasm Regression, Spontaneous
D000951:Antigens, Neoplasm; D001323:Autoantibodies; D051959:ELAV Proteins