title: Why do the numbers of laboratory animal procedures conducted continue to rise? An analysis of the Home Office Statistics of Scientific Procedures on Living Animals: Great Britain 2005.
abstract: The publication of the Statistics of Scientific Procedures on Living Animals: Great Britain 2005 once again provides evidence that the levels of animal experimentation in Great Britain are rising, the underlying reason for this being the continued and increasing reliance on genetically modified animals as model systems. There has been a gradual increase in fundamental research, as applied toxicological studies have declined. Of particular concern is the impact that the forthcoming REACH legislation will have and the apparent lack of urgency in facing up to this challenge. The major issues arising from the Statistics are discussed, including the increases in rabbit and primate procedures. The potential of newly validated and emerging techniques to counteract these worrying trends are also considered.
authors.affiliation: FRAME, Russell & Burch House, 96-98 North Sherwood Street, Nottingham, NG1 4EE, UK. michelle@frame.org.uk
authors.forename: Michelle
authors.initials: M
authors.lastname: Hudson
mesh_terms: D032761:Animal Experimentation / Q000706:statistics & numerical data*; D000826:Animal Testing Alternatives; D000818:Animals; D030801:Animals, Genetically Modified; D000830:Animals, Laboratory; D004353:Drug Evaluation, Preclinical / Q000706:statistics & numerical data* / Q000639:trends; D018675:Toxicity Tests / Q000706:statistics & numerical data* / Q000639:trends; D006113:United Kingdom