title: [Surgical management of obstructive sleep apnea].
abstract: BACKGROUND
  Obstructive sleep apnea (OSA) is a common disorder in adults, however it also occurs in neonates with severe mandibular hypoplasia. The clinical significance of OSA results from hypoxemia and sleep fragmentation due to a collapse of the upper airway. Recently OSA has received much attention due to its potentially serious consequences on cardiac function. Besides daytime sleepiness and fatigue life expectancy is significantly shortened by a higher risk for apoplectic insults and heart failures. This paper reviews common surgical procedures with an emphasis on jaw advancement procedures.
  
  
  METHODS
  In six adults (mean age 46,9 ys; 2 female, 4 male; BMI averaged 28kg/m(2)) suffering from OSA with a history of a long-lasting unsuccessful continuous positive airway pressure (CPAP) therapy a bimaxillary advancement was performed. The respiratory disturbance was preoperatively evaluated by polysomnography; daytime sleepiness was recorded according to the 'Epworth Sleepiness Scale'. Controls were performed six months after therapy. All patients had a regular intermaxillary relation. Bimaxillary advancement was planned and performed according to the principles of cranio-maxillofacial corrective surgery. To widen the posterior airway space much attention was focused on the advancement of the mandible by 10mm.
  
  
  RESULTS
  The apnea/hypopnea index decreased from preoperatively 37/h to 4/h after treatment. The minimal peripheral oxygen saturation increased from 78% to 89%, whereas the average oxygen saturation raised from 92 to 95%. The arousal index decreased from 24/h to 9/h. Periods of snoring were reduced from 29,5% to 6,9%. According to the 'Epworth Sleepiness Scale' the patients' estimation improved from a level of 11 to 4. Sleep had a recuperating effect. All surgical procedures were uneventful.
  
  
  CONCLUSIONS
  Standard treatment of OSA is the CPAP-therapy. In some patients, however, CPAP-therapy cannot be applied, fails or is not well accepted. A great variety of surgical procedures for the treatment of OSA have been described. Bimaxillary advancement in adults and osteodistraction in neonates are safe and successful surgical techniques for an immediate improvement in OSA. Osteodistraction treatment can help to avoid tracheotomy in neonates.
authors.affiliation: Friedrich-Alexander-Universität, Mund-, Erlangen-Nürnberg, Mund-, Kiefer- und Gesichtschirurgische Klinik, Glückstrasse 11, 91054 Erlangen, Germany. peter.kessler@mkg.imed.uni-erlangen.de
authors.forename: P
authors.initials: P
authors.lastname: Kessler
authors.forename: F
authors.initials: F
authors.lastname: Ruberg
authors.forename: H
authors.initials: H
authors.lastname: Obbarius
authors.forename: H
authors.initials: H
authors.lastname: Iro
authors.forename: F W
authors.initials: FW
authors.lastname: Neukam
mesh_terms: D000328:Adult; D045422:Continuous Positive Airway Pressure; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008437:Maxilla / Q000601:surgery*; D008875:Middle Aged; D019647:Oral Surgical Procedures; D017286:Polysomnography; D011183:Postoperative Complications / Q000209:etiology; D012189:Retrospective Studies; D020181:Sleep Apnea, Obstructive / Q000175:diagnosis / Q000209:etiology / Q000601:surgery*; D016896:Treatment Outcome