title: Secondary transport of amino acids in prokaryotes.
abstract: Amino acid transport is a ubiquitous phenomenon and serves a variety of functions in prokaryotes, including supply of carbon and nitrogen for catabolic and anabolic processes, pH homeostasis, osmoprotection, virulence, detoxification, signal transduction and generation of electrochemical ion gradients. Many of the participating proteins have eukaryotic relatives and are successfully used as model systems for exploration of transporter structure and function. Distribution, physiological roles, functional properties, and structure-function relationships of prokaryotic alpha-amino acid transporters are discussed.
authors.affiliation: Bereich Mikrobiologie, Department Biologie I, Ludwig-Maximilians-Universität München, D-80638, München, Germany. heinrich.jung@lrz.uni-muenchen.de
authors.forename: H
authors.initials: H
authors.lastname: Jung
authors.forename: T
authors.initials: T
authors.lastname: Pirch
authors.forename: D
authors.initials: D
authors.lastname: Hilger
mesh_terms: D026905:Amino Acid Transport Systems / Q000737:chemistry / Q000145:classification / Q000378:metabolism; D000596:Amino Acids / Q000378:metabolism*; D019843:Archaeal Proteins / Q000737:chemistry / Q000378:metabolism; D001426:Bacterial Proteins / Q000737:chemistry / Q000378:metabolism; D001665:Binding Sites; D001693:Biological Transport, Active; D008954:Models, Biological; D008958:Models, Molecular; D015394:Molecular Structure; D010802:Phylogeny; D011387:Prokaryotic Cells; D011487:Protein Conformation
chemical_list: D026905:Amino Acid Transport Systems; D000596:Amino Acids; D019843:Archaeal Proteins; D001426:Bacterial Proteins