title: Intraoral granulocytic sarcoma presenting as multiple maxillary and mandibular masses: a case report and literature review.
abstract: Granulocytic sarcoma (GS) is an unusual localized tumor composed of immature granulocytic precursor cells that occurs in extramedullary sites. However, GS involving the oral cavity is rare. We report a case of intraoral GS with an unusual clinical presentation, including a history of chronic myelogenous leukemia in remission, multiple maxillary and mandibular gingival masses mimicking acute inflammation that developed over a short period, complete remission after 1 week of treatment with imatinib mesylate (Gleevec), and no bone marrow or peripheral blood involvement over a 6-month follow-up period. To our knowledge, this is the first report of treatment of intraoral GS with Gleevec resulting in a complete remission.
authors.affiliation: Department of Oral and Maxillofacial Surgery, Affiliated Stomatological Hospital, Zhejiang University School of Medicine, Hangzhou, China. xzj66@zju.edu.cn
authors.forename: Zhijian
authors.initials: Z
authors.lastname: Xie
authors.forename: Feng
authors.initials: F
authors.lastname: Zhang
authors.forename: En
authors.initials: E
authors.lastname: Song
authors.forename: Weili
authors.initials: W
authors.lastname: Ge
authors.forename: Fudong
authors.initials: F
authors.lastname: Zhu
authors.forename: Ji'an
authors.initials: J
authors.lastname: Hu
mesh_terms: D000328:Adult; D000970:Antineoplastic Agents / Q000627:therapeutic use; D001549:Benzamides; D005260:Female; D006801:Humans; D000068877:Imatinib Mesylate; D007573:Jaw Neoplasms / Q000188:drug therapy / Q000473:pathology*; D010879:Piperazines / Q000627:therapeutic use; D011743:Pyrimidines / Q000627:therapeutic use; D012074:Remission Induction; D023981:Sarcoma, Myeloid / Q000188:drug therapy / Q000473:pathology*
chemical_list: D000970:Antineoplastic Agents; D001549:Benzamides; D010879:Piperazines; D011743:Pyrimidines; D000068877:Imatinib Mesylate