title: Food chromium content, dietary chromium intake and related biological variables in French free-living elderly.
abstract: Trivalent chromium (Cr3+) is an essential trace element involved in insulin function. Cr deficiencies result in decreased insulin sensitivity, glucose intolerance and an increased risk of diabetes. Cr status decreases with age suggesting that the elderly may be at high risk of Cr deficiency. This study aimed to provide information about the Cr content of foods in France and the Cr intake in French free-living elderly. We measured the food Cr content and daily Cr intake of freely chosen diets for 3 d in twelve French free-living elderly people and their Cr excretion and plasma hormonal related variables, leptin, insulin and cortisol. Considering the relationship between insulin resistance and oxidative stress, we also determined plasma thiobarbituric acid reactive substance, thiol groups and total and reduced glutathione. Although these subjects had well-balanced diets, their daily Cr intakes did not reach the French recommendations. The low Cr intakes were due to the low Cr density of the foods. We found a negative correlation between Cr intakes and insulin, BMI and leptin.
authors.affiliation: Laboratoire NVMC, EA 3746 - Université Joseph Fourier, 38700, Grenoble, France. Anne-Marie.Roussel@ujf-grenoble.fr
authors.forename: Anne-Marie
authors.initials: AM
authors.lastname: Roussel
authors.forename: Maud
authors.initials: M
authors.lastname: Andriollo-Sanchez
authors.forename: Monique
authors.initials: M
authors.lastname: Ferry
authors.forename: Noella A
authors.initials: NA
authors.lastname: Bryden
authors.forename: Richard A
authors.initials: RA
authors.lastname: Anderson
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000378:metabolism; D001628:Beverages / Q000032:analysis; D002857:Chromium / Q000008:administration & dosage* / Q000032:analysis / Q000652:urine; D004032:Diet; D002149:Energy Intake; D005260:Female; D005504:Food Analysis / Q000379:methods*; D005602:France; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D007328:Insulin / Q000097:blood; D020738:Leptin / Q000097:blood; D008297:Male; D018384:Oxidative Stress / Q000502:physiology
chemical_list: D007328:Insulin; D020738:Leptin; D002857:Chromium; D006854:Hydrocortisone