title: Cutaneous epithelioid angioleiomyoma with clear-cell change.
abstract: Epithelioid angioleiomyoma is rare in the skin and subcutis. We report here an unusual case of epithelioid angioleiomyoma with prominent clear-cell change. Smooth-muscle differentiation was confirmed by immunostains. The extensive clear-cell change in epithelial cells and the marked hyalinization and calcification made the histologic differential diagnosis challenging. Epithelioid angioleiomyoma shares some histologic characteristics with glomus tumors and seems to be an intermediate entity between angioleiomyomas and glomus tumors.
authors.affiliation: Department of Pathology, Health Science Center of Peking University, Beijing, China. liujianying@hsc.pku.edu.cn
authors.forename: Jian Ying
authors.initials: JY
authors.lastname: Liu
authors.forename: Song Lin
authors.initials: SL
authors.lastname: Liao
authors.forename: Jie
authors.initials: J
authors.lastname: Zheng
mesh_terms: D000199:Actins / Q000032:analysis; D000328:Adult; D018229:Angiomyoma / Q000737:chemistry / Q000175:diagnosis* / Q000473:pathology; D002114:Calcinosis / Q000175:diagnosis; D002454:Cell Differentiation; D003893:Desmin / Q000032:analysis; D003937:Diagnosis, Differential; D004817:Epidermis / Q000737:chemistry / Q000473:pathology*; D015622:Epithelioid Cells / Q000737:chemistry / Q000473:pathology*; D005260:Female; D005918:Glomus Tumor / Q000737:chemistry / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D006818:Hyalin / Q000378:metabolism; D007150:Immunohistochemistry; D032389:Myocytes, Smooth Muscle / Q000473:pathology; D012155:Reticulin / Q000032:analysis; D009418:S100 Proteins / Q000032:analysis; D012878:Skin Neoplasms / Q000737:chemistry / Q000175:diagnosis* / Q000473:pathology; D014617:Vacuoles / Q000473:pathology
chemical_list: D000199:Actins; D003893:Desmin; D012155:Reticulin; D009418:S100 Proteins