[Efficacy of surgical and therapeutic methods of repeated carotid ischemic stroke prophylaxis].
Comparative efficacy of surgical and therapeutic methods of repeated ischemic stroke prophylaxis at the patients with clinical symptoms of acute brain ischemia and carotid stenosis less 70% was analyzed. Three-year period of follow-up demonstrated that at the patients who have undergone carotid endarterectomy the repeated ischemic events were seen only at 4 (3.9%), and in the group of therapeutic prophylaxis--at 57 (52.7%). Carotid endarterectomy permits to reduce relative risk of repeated ischemic stroke from 0.77 in therapeutic prophylaxis to 0.07 in surgical treatment. Antiaggregant therapy after surgery is mandatory. Prolonged administration of Clopidogrel permits to reduce restenosis and thrombotic complication rate.
Akhmetov
V V
VV
Lemenev
V A
VA
Alekseeva
G S
GS
Stakhovskaia
L V
LV
Skvortsova
V I
VI
D000368:Aged; D001921:Brain / Q000098:blood supply* / Q000601:surgery*; D002545:Brain Ischemia / Q000517:prevention & control* / Q000601:surgery*; D016893:Carotid Stenosis / Q000517:prevention & control* / Q000601:surgery*; D002560:Cerebrovascular Circulation / Q000502:physiology; D003131:Combined Modality Therapy; D016894:Endarterectomy, Carotid / Q000379:methods* / Q000706:statistics & numerical data*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010507:Periodicity; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use*
D010975:Platelet Aggregation Inhibitors