title: [Study on the socio-economic risk factors on birth defects in Lvliang district of Shanxi province].
abstract: OBJECTIVE
  To study the risk factors in high prevalence district of birth defects (BD) to provide evidence for intervention development.
  
  
  METHODS
  Quantitative analysis had been carried out based on the investigation at three counties in Shanxi province. 491 useable questionnaires had been collected with a response rate as 94.6%. Binary logistic regression was performed to analyze the risk factors of BD.
  
  
  RESULTS
  Data from logistic regression analyses revealed that factors as: the status of family income, knowledge on healthy birth and rearing, behavior and illness during pregnancy were influencing the occurrence of BD, with OR values as 0.535, 3.265, 0.403 and 1.379 respectively. Better family income and knowledge on BD were negatively (P values are 0.000 and 0.001 respectively), while illness during pregnancy and alcohol intake of the husbands were positively correlated (P values are 0.005 and 0.012 respectively) to the occurrence of BD.
  
  
  CONCLUSIONS
  Measures as accelerating the development of local economy, providing education on BD knowledge to the couples, changing negative life style and improving the health status would reduce the risk of BD. Preconceptional-periconceptional care seemed to be the new idea for healthy pregnancy and healthy baby.
authors.affiliation: Institute of Population Research, Peking University, Beijing 100871, China.
authors.forename: Ju-Fen
authors.initials: JF
authors.lastname: Liu
authors.forename: Gong
authors.initials: G
authors.lastname: Chen
authors.forename: Lei
authors.initials: L
authors.lastname: Zhang
authors.forename: Xiang-Hua
authors.initials: XH
authors.lastname: Fan
authors.forename: Xiao-Ying
authors.initials: XY
authors.lastname: Zheng
mesh_terms: D002681:China / Q000453:epidemiology; D000013:Congenital Abnormalities / Q000191:economics / Q000453:epidemiology*; D005260:Female; D015438:Health Behavior; D006801:Humans; D007182:Income; D008297:Male; D011247:Pregnancy; D011248:Pregnancy Complications / Q000453:epidemiology; D012307:Risk Factors; D012923:Social Class