title: Modifying surfaces and interfaces for improved biomaterial performance.
abstract: Greater understanding of the fundamental processes that drive a body's response to an implant material is leading to new approaches in biomaterial surface engineering. Some recent work is reported. The discussion looks, respectively, at the important roles of the surface water layer and microscopic molecular domains, the new emphasis on conducting polymers and future developments.
authors.affiliation: IRC in Biomedical Materials, Queen Mary, University of London, UK. p.vadgama@qmul.ac.uk
authors.forename: P
authors.initials: P
authors.lastname: Vadgama
mesh_terms: D002448:Cell Adhesion; D020099:Coated Materials, Biocompatible / Q000737:chemistry*; D006046:Gold / Q000737:chemistry; D006493:Heparin / Q000737:chemistry; D016023:Integrins / Q000737:chemistry; D015603:Keratinocytes / Q000502:physiology; D010767:Phosphorylcholine / Q000737:chemistry; D011108:Polymers / Q000737:chemistry*; D011134:Polysaccharides / Q000737:chemistry; D011758:Pyrroles / Q000737:chemistry; D013499:Surface Properties; D014867:Water / Q000737:chemistry*
chemical_list: D020099:Coated Materials, Biocompatible; D016023:Integrins; D011108:Polymers; D011134:Polysaccharides; D011758:Pyrroles; D014867:Water; D010767:Phosphorylcholine; C067635:polypyrrole; D006046:Gold; D006493:Heparin