title: Nodular gastritis: an endoscopic indicator of Helicobacter Pylori infection.
abstract: We prospectively assessed the relationship between nodular gastritis and Helicobacter pylori infection. Of 1409 adults who underwent endoscopy for persistent dyspepsia between June 2004 and August 2005, 41 (2.9%) patients were diagnosed with nodular gastritis (11 [27%] men and 30 [73%] women). The mean age was 45.9 years. A control group of 65 patients without nodular gastritis was also evaluated. The prevalence of H. pylori infection was higher in patients with nodular gastritis than in controls (38/41 [93%] vs. 33/65 [51%]). Of 21 patients treated to eradicate H. pylori, the nodular gastritis pattern resolved or improved in 16 patients on subsequent endoscopy. This study suggests that a nodular pattern of the gastric mucosa on endocscopy is a good indicator for H. pylori infection in adults, with the high positive predictive value of 92.7%.
authors.affiliation: Department of Internal Medicine, Division of Gastroenterology, Mackay Memorial Hospital, No. 92, Sec. 2, Chungshan North Road, Taipei, Taiwan. mingjen.ch@msa.hinet.net
authors.forename: Ming-Jen
authors.initials: MJ
authors.lastname: Chen
authors.forename: Tsang-En
authors.initials: TE
authors.lastname: Wang
authors.forename: Wen-Hsiung
authors.initials: WH
authors.lastname: Chang
authors.forename: Ta-Chuan
authors.initials: TC
authors.lastname: Liao
authors.forename: Ching-Chung
authors.initials: CC
authors.lastname: Lin
authors.forename: Shou-Chuan
authors.initials: SC
authors.lastname: Shih
mesh_terms: D000328:Adult; D000368:Aged; D003937:Diagnosis, Differential; D005260:Female; D005500:Follow-Up Studies; D005753:Gastric Mucosa / Q000382:microbiology / Q000473:pathology; D005756:Gastritis / Q000175:diagnosis / Q000382:microbiology*; D005773:Gastroscopy; D016481:Helicobacter Infections / Q000150:complications* / Q000175:diagnosis / Q000453:epidemiology; D016480:Helicobacter pylori / Q000302:isolation & purification*; D006801:Humans; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D011379:Prognosis; D011446:Prospective Studies