Ionic-liquid-promoted palladium-catalyzed multicomponent cyclocarbonylation of o-iodoanilines and allenes to form methylene-2,3-dihydro-1H-quinolin-4-ones.
The palladium-catalyzed cyclocarbonylation reaction of o-iodoanilines with allenes and CO in 1-butyl-3-methylimidazolium hexafluorophosphate afforded 3-methylene-2,3-dihydro-1H-quinolin-4-ones in moderate to excellent yields under a low pressure (5 atm) of CO. The ionic liquid, as the solvent and promoter, enhances the efficiency of the cyclocarbonylation reaction. The recyclability of the system of ionic liquid/catalyst/ligand was also demonstrated.
Ye
Fangguo
F
Centre for Catalysis Research and Innovation, Department of Chemistry, University of Ottawa, 10 Marie Curie, Ottawa, Ontario K1N 6N5, Canada.
Alper
Howard
H
D000466:Alkadienes / Q000737:chemistry; D000814:Aniline Compounds / Q000737:chemistry*; D002384:Catalysis; D002625:Chemistry, Organic / Q000379:methods*; D052578:Ionic Liquids / Q000737:chemistry; D010165:Palladium / Q000737:chemistry*; D011804:Quinolines / Q000737:chemistry*
D000466:Alkadienes; D000814:Aniline Compounds; D052578:Ionic Liquids; D011804:Quinolines; C025947:propadiene; D010165:Palladium; C075715:3-iodoaniline