title: Evaluation of moxalactam with the BD phoenix system for detection of methicillin resistance in coagulase-negative staphylococci.
abstract: The performance of moxalactam with the BD Phoenix system for the detection of methicillin resistance in coagulase-negative staphylococci was evaluated by use of a collection of 186 strains. Moxalactam was a better drug as an indicator of methicillin resistance for mecA-positive strains than oxacillin and cefoxitin were. For strains other than Staphylococcus saprophyticus, a moxalactam MIC >16 microg/ml was indicative of methicillin resistance.
authors.affiliation: CHU de Bordeaux, Hôpital Pellegrin, Laboratoire de Bactériologie, Place Amélie Raba Léon, 33076 Bordeaux, France.
authors.forename: H
authors.initials: H
authors.lastname: Pupin
authors.forename: H
authors.initials: H
authors.lastname: Renaudin
authors.forename: O
authors.initials: O
authors.lastname: Join-Lambert
authors.forename: C
authors.initials: C
authors.lastname: Bébéar
authors.forename: F
authors.initials: F
authors.lastname: Mégraud
authors.forename: P
authors.initials: P
authors.lastname: Lehours
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001426:Bacterial Proteins / Q000235:genetics; D003030:Coagulase / Q000378:metabolism*; D006801:Humans; D016106:Methicillin Resistance / Q000235:genetics; D008826:Microbial Sensitivity Tests / Q000379:methods / Q000592:standards; D009070:Moxalactam / Q000494:pharmacology*; D046915:Penicillin-Binding Proteins; D011933:Reagent Kits, Diagnostic; D013210:Staphylococcus / Q000145:classification / Q000187:drug effects* / Q000201:enzymology / Q000235:genetics
chemical_list: D000900:Anti-Bacterial Agents; D001426:Bacterial Proteins; D003030:Coagulase; D046915:Penicillin-Binding Proteins; D011933:Reagent Kits, Diagnostic; C487789:mecA protein, Staphylococcus aureus; D009070:Moxalactam