title: Biotin responsive limb weakness.
abstract: We report acute onset quadriplegia in a ten year old boy associated with basal ganglia lesions due to biotin deficiency. Prolonged raw egg consumption was identified as predisposing factor for biotin deficiency. Treatment with biotin resulted in remarkable recovery.
authors.affiliation: Department of Pediatrics, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Pondicherry 605 006, India. adhisivam1975@yahoo.co.uk
authors.forename: B
authors.initials: B
authors.lastname: Adhisivam
authors.forename: Deonath
authors.initials: D
authors.lastname: Mahto
authors.forename: S
authors.initials: S
authors.lastname: Mahadevan
mesh_terms: D001480:Basal Ganglia Diseases / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D001710:Biotin / Q000172:deficiency*; D002648:Child; D004531:Eggs / Q000009:adverse effects*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D011782:Quadriplegia / Q000188:drug therapy / Q000209:etiology*; D014804:Vitamin B Deficiency / Q000175:diagnosis / Q000188:drug therapy*
chemical_list: D001710:Biotin