Endometrial carcinoma first presenting as paraneoplastic cerebellar degeneration.
BACKGROUND
Paraneoplastic degeneration (PCD) is an immune-mediated disorder affecting the cerebellum, characterized by subacute onset of cerebellar dysfunction progressing to severe disability, and is associated with an underlying malignancy. Ovarian carcinoma and breast carcinoma are commonly implicated.


METHODS
We report a rare case PCD in an elderly woman, later diagnosed with endometrial carcinoma.


CONCLUSIONS
PCD is an unusual and rare manifestation of gynecological malignancies, including endometrial carcinoma, and a high degree of suspicion is required in these cases in order to make the correct diagnosis.
Erez
Yair
Y
Department of Obstetrics and Gynecology, Hadassah Medical Center, Ein-Kerem, Jerusalem, IL POB 12000, Israel. erezyair@gmail.com
Rojansky
Nathan
N
Shveiky
David
D
Ben-Meir
Assaf
A
Benshushan
Avi
A
D000368:Aged; D016889:Endometrial Neoplasms / Q000175:diagnosis* / Q000276:immunology; D005260:Female; D006801:Humans; D020362:Paraneoplastic Cerebellar Degeneration / Q000175:diagnosis* / Q000276:immunology