title: Sonographic findings in a model of ischemia-induced necrotizing enterocolitis with pathological correlations.
abstract: OBJECTIVE
  To evaluate sonographic findings in ischemic enterocolitis (IEC) and correlate with pathologic findings in an experimental study.
  
  
  METHODS
  Ischemic enterocolitis was induced with ligation of the superior mesenteric artery in 20 rabbits. Plain radiography and ultrasonography (US) were performed. US was done hourly after the ligation using 10 MHz linear probe. US findings were categorized into 2 groups according to the bowel wall echogenicity; the echogenic dots (ED) group and the circumferential granular echogenicity (CGE) group. US findings were compared with the specimen radiography and the histopathology.
  
  
  RESULTS
  On US, ED were seen in the bowel of all rabbits after SMA ligation (2.2 +/- 1.3 hours [standard deviation]) and CGE in 16 rabbits (4.1 +/- 0.9 hours). On the specimen radiographs, multiple radiolucent air bubbles were present. Comparing the ED and CGE group, histopathological findings revealed the CGE group had severer injury of the bowel wall than the ED group. On plain radiography, there was progressive bowel distention, but pneumatosis intestinalis (PI) was not evident.
  
  
  CONCLUSIONS
  ED or CGE are the sonographic findings of ischemic enterocolitis, and bowel wall echogenicity might reflect the degree of ischemic injury.
authors.affiliation: Department of Radiology, CHA Hospital, College of Medicine, Pochon CHA University, Korea.
authors.forename: Wha-Young
authors.initials: WY
authors.lastname: Kim
authors.forename: In-One
authors.initials: IO
authors.lastname: Kim
authors.forename: Woo Sun
authors.initials: WS
authors.lastname: Kim
authors.forename: Kyung Mo
authors.initials: KM
authors.lastname: Yeon
authors.forename: Gwang Il
authors.initials: GI
authors.lastname: Kim
authors.forename: Sun Wha
authors.initials: SW
authors.lastname: Lee
authors.forename: Jeong Soo
authors.initials: JS
authors.lastname: Suh
authors.forename: Hye-Young
authors.initials: HY
authors.lastname: Choi
authors.forename: Kyu-Jin
authors.initials: KJ
authors.lastname: Chang
mesh_terms: D000818:Animals; D020345:Enterocolitis, Necrotizing / Q000000981:diagnostic imaging* / Q000209:etiology / Q000473:pathology*; D007422:Intestines / Q000000981:diagnostic imaging / Q000473:pathology; D007511:Ischemia / Q000000981:diagnostic imaging / Q000473:pathology; D008026:Ligation; D017538:Mesenteric Artery, Superior; D023421:Models, Animal; D011817:Rabbits; D011859:Radiography; D014463:Ultrasonography