title: [Total mastectomy and axillary dissection with conservation of the nipple-areola complex, and immediate reconstruction with artificial prosthesis in the treatment of early breast cancer].
abstract: OBJECTIVE
  To study the feasibility of total mastectomy and axillary dissection with conservation of the nipple-areola complex, and immediate reconstruction with artificial prosthesis in the treatment of early breast cancer.
  
  
  METHODS
  The 20 patients with breast cancer (TNM stage I, 6 patients; stage II, 14 patients) underwent the total mastectomy axillary dissection with conservation of the nipple-areola complex, and immediate reconstruction with artificial prosthesis. Post-operation they were given chemotherapy, radiotherapy, endocrine therapy.
  
  
  RESULTS
  The mean follow-up for the entire group of 20 patients was 52.3 months, eighteen patients were more than 36 months. All patients were still alive, without local or regional recurrences. One patient suffered from multiple metastasis of liver and bone nine months after the operation, who has living five years now.
  
  
  CONCLUSIONS
  Total mastectomy and axillary dissection with conservation of the nipple-areola complex, and immediate reconstruction with artificial prosthesis on selected patients with breast cancer is an oncologically acceptable procedure with superior cosmetic results, without increasing the risk of local recurrences, complications and influencing the effects of postoperative adjuvant treatment.
authors.affiliation: Bethune-Laval Oncology Unit, First Hospital, Jilin University, Changchun 130021, China.
authors.forename: Zhi-Min
authors.initials: ZM
authors.lastname: Fan
authors.forename: Dong
authors.initials: D
authors.lastname: Song
authors.forename: Lei
authors.initials: L
authors.lastname: Wang
authors.forename: Tong
authors.initials: T
authors.lastname: Fu
authors.forename: Ming
authors.initials: M
authors.lastname: Yang
authors.forename: Gou-Jin
authors.initials: GJ
authors.lastname: Liu
mesh_terms: D000328:Adult; D019928:Breast Implantation; D001943:Breast Neoplasms / Q000473:pathology / Q000601:surgery*; D005240:Feasibility Studies; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015411:Mastectomy, Modified Radical / Q000379:methods*; D009367:Neoplasm Staging; D009558:Nipples / Q000601:surgery