title: [Current status of islet transplantation].
abstract: Due to the numerous advances in islet transplantation in the last few years, clinical outcomes following this procedure are continually improving. Novel immunosuppression protocols, improved donor and recipient selection, and careful attention to the process of organ extraction, preservation and islet isolation have contributed to long-term success. The present article reviews the results of clinical islet transplantation and their relationship with the different advances introduced. The use of new islet sources such as living and non-heart-beating donors, as well as recent advances in our knowledge of the mechanisms of rejection and its prevention, are also reviewed.
authors.affiliation: Departamento de Cirugía, Facultad de Medicina, Universidad Complutense de Madrid, Madrid, España. jose_balibrea@yahoo.es
authors.forename: José María
authors.initials: JM
authors.lastname: Balibrea del Castillo
authors.forename: Elena
authors.initials: E
authors.lastname: Vara Ameigeiras
authors.forename: Javier
authors.initials: J
authors.lastname: Arias-Díaz
authors.forename: M Cruz
authors.initials: MC
authors.lastname: García Martín
authors.forename: Juan Carlos
authors.initials: JC
authors.lastname: García-Pérez
authors.forename: José Luis
authors.initials: JL
authors.lastname: Balibrea Cantero
mesh_terms: D006084:Graft Rejection / Q000517:prevention & control; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D016381:Islets of Langerhans Transplantation / Q000379:methods* / Q000592:standards*; D019520:Living Donors; D013030:Spain
chemical_list: D007166:Immunosuppressive Agents