title: [A case of hepatocellar carcinoma associated with mixed connective tissue disease].
abstract: A 79-year-old woman, who had been treated because of mixed connective tissue disease (MCTD), was admitted to the hospital for the intensive examination of a hepatic tumor that was unexpectedly found on computed tomography. The hepatic tumor was approximately 40 mm in diameter. Her transaminase levels were slightly elevated but hepatic virus markers were negative. However, a liver aspiration biopsy revealed moderately differentiated hepatocellular carcinoma (HCC). In the surrounding non-tumor area, nonspecific reactive hepatitis was detected. MCTD associated with HCC has not yet been reported in the past. This case appears to be very interesting in terms of the etiology of HCC.
authors.affiliation: Second Department of Internal Medicine, Fukushima Medical University School of Medicine.
authors.forename: Kyoko
authors.initials: K
authors.lastname: Monoe
authors.forename: Yukiko
authors.initials: Y
authors.lastname: Kanno
authors.forename: Hironobu
authors.initials: H
authors.lastname: Saito
authors.forename: Kazumichi
authors.initials: K
authors.lastname: Abe
authors.forename: Atsushi
authors.initials: A
authors.lastname: Takahashi
authors.forename: Junko
authors.initials: J
authors.lastname: Takiguchi
authors.forename: Tsuyoshi
authors.initials: T
authors.lastname: Rai
authors.forename: Takuto
authors.initials: T
authors.lastname: Hikichi
authors.forename: Hiromasa
authors.initials: H
authors.lastname: Ohira
mesh_terms: D000368:Aged; D006528:Carcinoma, Hepatocellular / Q000209:etiology*; D005260:Female; D006801:Humans; D008113:Liver Neoplasms / Q000209:etiology*; D008947:Mixed Connective Tissue Disease / Q000150:complications*