title: [Course and prognosis of a case of central pontine myelinolysis in eating behavior disorder].
abstract: Central pontine myelinolysis (CPM) is a serious disorder that has been described in multiple diseases, generally involving important metabolic and hydroelectrolyte alterations. Although initially, its prognosis was usually fatal, there are a growing number of cases where the clinical symptoms begin abruptly and end after a short period, albeit with a persistence of the neuroimaging lesions. The case of a 22 year-old woman with a 6 year history of serious eating disorder with important physical deterioration and neurological and psychiatric symptoms suggestive of CPM is described. Despite the confirmation of the brain lesions through magnetic resonance imaging, neurological and psychiatric symptoms fully disappeared within a few weeks while the typical lesions of CPM remained. Although the risk of appearance of CPM exists during the course of an eating disorder, its prognosis does not seem to be as fatal as it was previously thought. Close monitoring of the clinical symptoms and neuroimaging findings should be carried out in these patients during the first months.
authors.affiliation: Servicio de Psiquiatría, Hospital San Rafael, P. Valle Hebron 107-117, 08025 Barcelona. 32698nrn@comb.es
authors.forename: N
authors.initials: N
authors.lastname: Ramírez
authors.forename: B
authors.initials: B
authors.lastname: Arranz
authors.forename: C
authors.initials: C
authors.lastname: Martín
authors.forename: L
authors.initials: L
authors.lastname: San
mesh_terms: D000328:Adult; D000856:Anorexia Nervosa / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D018450:Disease Progression; D005260:Female; D006801:Humans; D017590:Myelinolysis, Central Pontine / Q000150:complications* / Q000188:drug therapy* / Q000473:pathology; D010288:Parenteral Nutrition
chemical_list: D000900:Anti-Bacterial Agents