Nasofacial phycomycosis: persistence pays.
Nasofacial phycomycosis caused by Conidiobolus is a rare fungal infection most often encountered in the developing world in conditions of poverty. A clinical presentation of the natural history of this condition observed over a period of 6 years by a visiting volunteer surgical team demonstrates the role of multimodality surgical and antifungal drug treatment in producing a successful outcome. The particular sensitivity of this infection to the new generation antifungal Voriconazole is noted.
Moore
Mark Harold
MH
Royal Australasian College of Surgeons Specialist Surgical Project, East Timor. mhmoore@internode.net.au
Murphy
Dan
D
James
Craig
C
D000328:Adult; D000935:Antifungal Agents / Q000494:pharmacology / Q000627:therapeutic use*; D020092:Conidiobolus / Q000187:drug effects* / Q000302:isolation & purification; D025141:Drug Resistance, Fungal; D005148:Facial Dermatoses / Q000188:drug therapy* / Q000601:surgery; D005260:Female; D006801:Humans; D017964:Itraconazole / Q000494:pharmacology / Q000627:therapeutic use; D011743:Pyrimidines / Q000494:pharmacology / Q000627:therapeutic use*; D049648:Timor-Leste; D014230:Triazoles / Q000494:pharmacology / Q000627:therapeutic use*; D065819:Voriconazole; D020096:Zygomycosis / Q000188:drug therapy* / Q000601:surgery
D000935:Antifungal Agents; D011743:Pyrimidines; D014230:Triazoles; D017964:Itraconazole; D065819:Voriconazole