Microtubule organization: cell shape is destiny.
A simple self-assembly pathway generates cytoplasmic microtubule bundles that can locate the cell center and guide spindle assembly in fission yeast. The cylindrical cell shape automatically corrects spindle orientation errors, rendering a checkpoint unnecessary.
Haase
Steven B
SB
Biology Department, Duke University, Durham, NC 27710, USA. shaase@duke.edu
Lew
Daniel J
DJ
D000818:Animals; D048430:Cell Shape; D008870:Microtubules / Q000378:metabolism*; D059828:Plant Cells; D012568:Schizosaccharomyces / Q000166:cytology / Q000378:metabolism; D008941:Spindle Apparatus / Q000378:metabolism