Two new triterpenoids and a steroidal glycoside from the aerial parts of Ocimum basilicum.
Studies on the chemical constituents of the aerial parts of Ocimum basilicum have led to the isolation of three new compounds, basilol (1), ocimol (2), and basilimoside (3), along with two known constituents betulinic acid and oleanolic acid. The structures of the new constituents have been elucidated through spectral studies including 2D-NMR experiments (HMQC, HMBC, COSY, NOESY, and J-resolved) and chemical transformation, as p-formylphenyl 3beta-hydroxyolean-12-en-28-oate (1), 2-methoxy-4-carbomethoxyphenyl 3beta-hydroxy-lup-20(29)-en-28-oate (2), and (22E)-24xi-ethyl-25-methylcholesta-5,22-diene-3beta-ol-3-O-D-glucopyranoside (3).
Siddiqui
Bina Shaheen
BS
International Center for Chemical Sciences, HEJ Research Institute of Chemistry, University of Karachi, Pakistan. bina@khi.comsats.net.pk
Aslam
Huma
H
Ali
Syed Tariq
ST
Begum
Sabira
S
Khatoon
Nasima
N
D006027:Glycosides / Q000032:analysis* / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D018649:Ocimum basilicum / Q000737:chemistry*; D021241:Spectrometry, Mass, Electrospray Ionization; D016339:Spectrometry, Mass, Fast Atom Bombardment; D013056:Spectrophotometry, Ultraviolet; D014315:Triterpenes / Q000032:analysis* / Q000737:chemistry
D006027:Glycosides; D014315:Triterpenes