title: Positron emission tomography for predicting malignancy of sinonasal inverted papilloma.
abstract: BACKGROUND
  Sinonasal inverted papilloma (IP) is an uncommon nasal tumor. It is known for being locally invasive and recurrent, with a high probability of malignant transformation. Accurate initial staging and close surveillance are critical in the management of the disease.
  
  
  RESULTS
  Fluorine-18 fluorodeoxyglucose positron emission tomography (FDG PET) was performed in 5 patients with IP. High FDG uptake (maximum standardized uptake (SUVmax) value >3.0) was observed in all patients, and 2 patients with IP associated with squamous cell carcinoma (SCC) exhibited higher SUVmax values.
  
  
  CONCLUSIONS
  The SUVmax value of a sinonasal tumor can warn the surgeon of the probability of an associated malignancy, even when preoperative biopsy demonstrates a purely benign papilloma.
authors.affiliation: Department of Otolaryngology, University of Toyama, Toyama, Japan. hshojaku@med.u-toyama.ac.jp
authors.forename: Hideo
authors.initials: H
authors.lastname: Shojaku
authors.forename: Michiro
authors.initials: M
authors.lastname: Fujisaka
authors.forename: Satsuki
authors.initials: S
authors.lastname: Yasumura
authors.forename: Masayuki
authors.initials: M
authors.lastname: Ishida
authors.forename: Masahito
authors.initials: M
authors.lastname: Tsubota
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Nishida
authors.forename: Yukio
authors.initials: Y
authors.lastname: Watanabe
authors.forename: Masaya
authors.initials: M
authors.lastname: Kawano
authors.forename: Masashi
authors.initials: M
authors.lastname: Shimizu
authors.forename: Jyunya
authors.initials: J
authors.lastname: Fukuoka
mesh_terms: D000368:Aged; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008297:Male; D008875:Middle Aged; D018308:Papilloma, Inverted / Q000000981:diagnostic imaging*; D010255:Paranasal Sinus Neoplasms / Q000000981:diagnostic imaging*; D049268:Positron-Emission Tomography / Q000379:methods*; D011379:Prognosis; D019275:Radiopharmaceuticals; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18