[Regulatory network of transcription factors: their key role in the development and function of pancreas].
Recent molecular biological studies of the pancreatic development have shed new light on the cause of MODY and diabetes mellitus type 2. The identification of transcription factors participating in the regulatory networks cooperating in the development and in adult exocrine and endocrine pancreas enabled the better understanding of the genetic background and subsequent phenotypic features of diabetes.
Lukásová
P
P
Endokrinologický ústav, Praha. plukasova@endo.cz
Vcelák
J
J
Vanková
M
M
Vejrazková
D
D
Bendlová
B
B
D000818:Animals; D003924:Diabetes Mellitus, Type 2 / Q000235:genetics* / Q000378:metabolism; D006801:Humans; D009154:Mutation; D010179:Pancreas / Q000196:embryology / Q000254:growth & development / Q000378:metabolism / Q000502:physiology*; D014157:Transcription Factors / Q000235:genetics / Q000502:physiology*
D014157:Transcription Factors