title: Chemometric analysis of complex hyphenated data. Improvements of the component detection algorithm.
abstract: Component detection algorithm (CODA) is a method to quickly extract the high-quality mass chromatograms from complex liquid chromatography/electrospray ionization mass spectrometry (LC/MS) data sets, saving operators hours of analysis time. It appeared, however, that mass chromatograms with a limited baseline problem were ignored. This paper describes several methods to increase the tolerance for mass chromatograms with a baseline.
authors.affiliation: Eigenvector Research, Inc., 3905 West Eaglerock Drive, Wenatchee, WA 98801, USA. windig@eigenvector.com
authors.forename: W
authors.initials: W
authors.lastname: Windig
authors.forename: W F
authors.initials: WF
authors.lastname: Smith
mesh_terms: D000465:Algorithms; D002853:Chromatography, Liquid / Q000379:methods*; D021241:Spectrometry, Mass, Electrospray Ionization / Q000379:methods*