title: False positivity of FDG-PET/CT in a child with Hodgkin disease.
abstract: Role of Positron Emission Tomography (PET) with F-18-2-fluoro-2-deoxy-D-glucose (FDG) in staging of Hodgkin disease is well established despite several controversies. We report a Stage III Hodgkin lymphoma patient with false positive FDG-PET/CT results. Seven-year-old male with Hodgkin lymphoma was in remission at end of chemotherapy. At third and fourth month of postchemotherapy follow-up, increased Gallium uptake and positive FDG-PET/CT in right lower quadrant of abdomen was observed. Open biopsy revealed lymphoid hyperplasia. He has been followed for 21 months without any evidence of disease. Despite its documented benefit, we believe that results of FDG-PET/CT should be interpreted with great caution in order to avoid unnecessary interventions.
authors.affiliation: Pediatric Hematology-Oncology, Marmara University Medical Center, Altunizade, Istanbul, Turkey.
authors.forename: Dildar Bahar
authors.initials: DB
authors.lastname: Beker
authors.forename: Su Gulsun
authors.initials: SG
authors.lastname: Berrak
authors.forename: Cengiz
authors.initials: C
authors.lastname: Canpolat
authors.forename: Halil
authors.initials: H
authors.lastname: Tugtepe
authors.forename: Tunc
authors.initials: T
authors.lastname: Ones
authors.forename: Tulay
authors.initials: T
authors.lastname: Tecimer
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002648:Child; D005189:False Positive Reactions; D005708:Gallium; D019298:Glucose-6-Phosphate / Q000031:analogs & derivatives*; D006689:Hodgkin Disease / Q000175:diagnosis* / Q000188:drug therapy; D006801:Humans; D008297:Male; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis*; D009367:Neoplasm Staging; D049268:Positron-Emission Tomography; D019275:Radiopharmaceuticals; D014057:Tomography, X-Ray Computed
chemical_list: D019275:Radiopharmaceuticals; C047515:2-fluoro-2-deoxyglucose-6-phosphate; D019298:Glucose-6-Phosphate; D005708:Gallium