title: Randomized, double-blind, sham-controlled evaluation of the effect of functional continuous magnetic stimulation in patients with urgency incontinence.
abstract: OBJECTIVE
  To evaluate the effect of functional continuous magnetic stimulation (FCMS) on urgency incontinence in randomized, sham-controlled manner.
  
  
  METHODS
  Thirty-nine patients with urgency incontinence, 16 males and 23 females (aged 66.0 +/- 16.5 years), who were refractory to pelvic floor muscle training (PFMT), were randomly assigned either to the treatment schedule performing 10-week active treatment, followed by 4-week non-treatment interval and then by 10-week sham treatment (A-S, n = 20) or to that performing the sham treatment first followed by 10-week active treatment (S-A, n = 19).
  
  
  RESULTS
  At 10 weeks, the number of leaks/week, the total score of the International Consultation on Incontinence-Questionnaire: Short Form (ICIQ-SF), and maximum cystometric capacity (MCC) were significantly improved as compared with the initial levels (P < 0.001, P < 0.001, and P = 0.003, respectively) in the former group, but not in the latter group. Four (20.0%) patients were cured in the A-S group, while no patient was cured in the S-A group. At the end of the A-S schedule (24 weeks of study), the effect of the active treatment was still maintained at a significantly improved level, as compared with the initial level. At the end of the S-A schedule, the number of leaks/week was significantly improved as compared with the initial level and with its 10-week level (P < 0.001 and P = 0.049, respectively), as well as ICIQ-SF total score (P = 0.001 and P = 0.006, respectively). MCC significantly increased from its initial level (P = 0.030).
  
  
  CONCLUSIONS
  Magnetic stimulation was effective on urgency incontinence in comparison to sham stimulation in this small patient group.
authors.affiliation: Department of Urology, Koshigaya Hospital, Dokkyo Medical University, Saitama, Japan.
authors.forename: Tsuneki
authors.initials: T
authors.lastname: Suzuki
authors.forename: Kosaku
authors.initials: K
authors.lastname: Yasuda
authors.forename: Tomonori
authors.initials: T
authors.lastname: Yamanishi
authors.forename: Satoshi
authors.initials: S
authors.lastname: Kitahara
authors.forename: Hideo
authors.initials: H
authors.lastname: Nakai
authors.forename: Shin
authors.initials: S
authors.lastname: Suda
authors.forename: Hiromi
authors.initials: H
authors.lastname: Ohkawa
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D004311:Double-Blind Method; D004599:Electric Stimulation Therapy; D005260:Female; D006801:Humans; D008280:Magnetics / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D010812:Physical Stimulation; D016896:Treatment Outcome; D014550:Urinary Incontinence, Stress / Q000628:therapy*; D014563:Urodynamics / Q000502:physiology