title: Novel substrates.
abstract: Enteral and parenteral feeds need at least to contain adequate amounts of water, energy, protein, electrolytes, vitamins and trace elements. Ready-manufactured parenteral feeds for example are incomplete because of shelf-life constraints and require the addition of vitamins (especially) and trace elements. Acute vitamin deficiencies, notably thiamine deficiency, can be precipitated if this is not adhered to. An increasing interest, however, exists in the use of feeds containing substrates, which are intended to improve patient outcome in particular clinical circumstances. The purpose of this article is to examine as to what is available and make recommendations on their use. It deals with artificial feeds only - disease-specific diets are outside our remit.
authors.affiliation: Barts and the London, Queen Mary's School of Medicine and Dentistry, London, UK.
authors.forename: Mahmood
authors.initials: M
authors.lastname: Wahed
authors.forename: Michael
authors.initials: M
authors.lastname: Geoghegan
authors.forename: Jeremy
authors.initials: J
authors.lastname: Powell-Tuck
mesh_terms: D000596:Amino Acids / Q000627:therapeutic use; D004750:Enteral Nutrition / Q000379:methods*; D006801:Humans; D018977:Micronutrients / Q000627:therapeutic use*; D008903:Minerals / Q000627:therapeutic use; D009844:Oligosaccharides / Q000627:therapeutic use; D010288:Parenteral Nutrition / Q000379:methods*; D014815:Vitamins / Q000627:therapeutic use
chemical_list: D000596:Amino Acids; D018977:Micronutrients; D008903:Minerals; D009844:Oligosaccharides; D014815:Vitamins; C116580:fructooligosaccharide