[Mo(Tm(Me))(O)2Cl]: an alternative functional model of sulfite oxidase.
The hydrotris(methimazolyl)borate anion (TmMe) has been used to synthesize an alternative functional model ([Mo(TmMe)(O)2Cl]) of the metalloenzyme sulfite oxidase. It has been shown that the complex undergoes oxygen atom transfer chemistry and that it performs the primary function of the enzyme, sulfite oxidation. A method using ion chromatography has been developed to definitively prove that sulfite is oxidized to sulfate. Employment of a soft tripodal ligand has allowed us to tune the redox potentials of our complex so that they are significantly closer to those reported for sulfite oxidase.
Wallace
Dawn
D
Department of Pure & Applied Chemistry, University of Strathclyde, 295 Cathedral Street, Glasgow G1 1XL, UK. dawn.wallace.100@strath.ac.uk
Gibson
Lorraine T
LT
Reglinski
John
J
Spicer
Mark D
MD