title: Expression of adhesion molecules during normal pregnancy.
abstract: We review the available information regarding the role of adhesive molecules as potential participants in the complex events of fertilization, embryogenesis, implantation and placentation. Studies that specifically relate to the expression and modulation of adhesive molecules in fertilization, embryogenesis, and implantation have been identified in the literature and by Medline searches. Cell-cell and cell-extracellular matrix interactions play a critical role in various developmental processes and in the cascade of events that lead to implantation and to the normal development of the fetus during pregnancy. Adhesion molecules influence, directly or indirectly, numerous aspects of cell behaviour, cell migration, cell growth, cell survival, cell proliferation, angiogenesis, invasion and metastasis.
authors.affiliation: Department of Obstetrics and Gynaecology, City Hospital, Birmingham, UK.
authors.forename: J
authors.initials: J
authors.lastname: Pafilis
authors.forename: A
authors.initials: A
authors.lastname: Batistatou
authors.forename: A
authors.initials: A
authors.lastname: Iliopoulou
authors.forename: E
authors.initials: E
authors.lastname: Tsanou
authors.forename: A
authors.initials: A
authors.lastname: Bakogiannis
authors.forename: G
authors.initials: G
authors.lastname: Dassopoulos
authors.forename: K
authors.initials: K
authors.lastname: Charalabopoulos
mesh_terms: D000818:Animals; D015815:Cell Adhesion Molecules / Q000096:biosynthesis*; D002465:Cell Movement / Q000502:physiology; D049109:Cell Proliferation; D002470:Cell Survival / Q000502:physiology; D010064:Embryo Implantation / Q000502:physiology; D005260:Female; D047109:Fetal Development / Q000502:physiology; D005786:Gene Expression Regulation / Q000502:physiology*; D006801:Humans; D018919:Neovascularization, Physiologic / Q000502:physiology; D010929:Placentation / Q000502:physiology; D011247:Pregnancy / Q000378:metabolism*
chemical_list: D015815:Cell Adhesion Molecules