title: Metabolism of parthenin by Beauveria bassiana ATCC 7159.
abstract: Two new metabolites were isolated from the biotransformation reaction of parthenin by Beauveria bassiana ATCC 7159 along with the known naturally occurring sesquiterpene lactones hymenolin and dihydrocoronopilin. The new metabolites: are 3beta,4beta,6beta-trihydroxy-10alphaH,11alpha-methyl-ambrosa-1 -en-12-oic acid-gamma-lactone and 3alpha,6beta-dihydroxy-4beta-hydroperoxy-10alphaH, 11alpha-methyl-ambrosa-1-en-12-oic acid-gamma-lactone. The structure elucidation of these compounds was achieved by different spectroscopic methods.
authors.affiliation: Department of Pharmacognosy, Faculty of Pharmacy, University of Mansoura, Mansoura, Egypt.
authors.forename: O B
authors.initials: OB
authors.lastname: Abdel Halim
authors.forename: G T
authors.initials: GT
authors.lastname: Maatooq
authors.forename: A M
authors.initials: AM
authors.lastname: Marzouk
mesh_terms: D052982:Beauveria / Q000378:metabolism*; D005285:Fermentation; D017665:Hydroxyl Radical / Q000378:metabolism; D009682:Magnetic Resonance Spectroscopy; D008968:Molecular Conformation; D012717:Sesquiterpenes / Q000032:analysis* / Q000378:metabolism; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet
chemical_list: C519216:3alpha,6beta-dihydroxy-4beta-hydroperoxy-10alphaH,11alpha-methyl-ambrosa-1-en-12-oic acid-gamma-lactone; C519215:3beta,4beta,6beta-trihydroxy-10alphaH,11alpha-methyl-ambrosa-1 -en-12-oic acid-gamma-lactone; D012717:Sesquiterpenes; D017665:Hydroxyl Radical; C022097:parthenin