Pulmonary sarcoidosis in a patient with ankylosing spondylitis treated with infliximab.
We present a case of a 34 year-old male diagnosed with ankylosing spondylitis. After two years of treatment with infliximab, the patient developed a clinical picture compatible with stage II thoracic sarcoidosis. These findings resulted in the interruption of infliximab therapy. The patient was not administered new treatment since respiratory function testing did not confirm harmful repercussions. After a follow-up of 1 year, the patient is asymptomatic and radiologic tests show complete resolution of pulmonary infiltrates and mediastinal and bilateral hilar lymphad- enopathy.
Almodóvar
R
R
Rheumatology Unit, Alcorcón Hospital Foundation, Madrid, Spain. ralmodovar@fhalcorcon.es
Izquierdo
M
M
Zarco
P
P
Javier Quirós
F
F
Mazzucchelli
R
R
Steen
B
B
D000328:Adult; D000911:Antibodies, Monoclonal / Q000009:adverse effects*; D018501:Antirheumatic Agents / Q000009:adverse effects*; D006099:Granuloma / Q000473:pathology; D006801:Humans; D000069285:Infliximab; D008297:Male; D017565:Sarcoidosis, Pulmonary / Q000139:chemically induced* / Q000473:pathology / Q000628:therapy; D013167:Spondylitis, Ankylosing / Q000188:drug therapy; D036542:Tomography, Spiral Computed
D000911:Antibodies, Monoclonal; D018501:Antirheumatic Agents; D000069285:Infliximab