Copper-mediated synthesis of tertiary diaryl squaramides.
Tertiary aryl squaramides were synthesized by using copper catalyzed C-N bond-formation with L-proline as the ligand. Symmetrical diaryl squaramides could be prepared in a one-pot reaction by using excess aryl bromide with varying yields. Unsymmetrical derivatives were prepared by sequential arylation. Yields of the diarylated products were highly sensitive to steric effects.
Ramalingam
Vijayakumar
V
Department of Chemistry and Biochemistry, Queens College and the Graduate Center of the City University of New York, Flushing, New York 11367-1597, USA.
Bhagirath
Niala
N
Muthyala
Rajeev S
RS
D000577:Amides / Q000737:chemistry*; D003300:Copper / Q000737:chemistry*; D008024:Ligands; D015394:Molecular Structure
D000577:Amides; D008024:Ligands; D003300:Copper