title: Does having insurance affect differences in clinical presentation between Hispanic and non-Hispanic white women with breast cancer?
abstract: BACKGROUND
  Hispanic women with breast cancer present differently than do non-Hispanic white (NHW) women. Lack of access to care has been offered as an explanation for these differences. In this study breast cancer presentation was examined in Hispanic women in a comprehensive, equal-access health care system.
  
  
  METHODS
  Hispanic and NHW breast cancer cases registered between 1995 and 2004 in the Kaiser Permanente of Colorado Tumor Registry were compared by age at diagnosis, stage, tumor grade, size, and receptor status. Multivariate logistic regression was performed to generate age-adjusted odds ratios by ethnicity and each tumor characteristic.
  
  
  RESULTS
  A total of 139 Hispanic women and 2118 NHW women with breast cancer were identified. Hispanic women had a mean average age at diagnosis of 56 years compared with 61 years for NHW women (P < .0001). Use of mammographic screening services in the prior 2 years was similar by ethnicity. Relative to NHW women, Hispanic women had age-adjusted odds ratios of 2.70 (95% confidence interval [CI]: 1.26-5.77) for having stage IV disease, 2.25 (95% CI: 1.39-3.67) for having poorly differentiated tumors, 2.16 (95% CI: 1.26-3.69) for having a tumor greater than 5 cm, and 1.88 (95% CI: 1.24-2.81) for having estrogen receptor-negative tumors.
  
  
  CONCLUSIONS
  Despite equal access to health care services, differences persist in the size, stage, and grade of breast cancer for Hispanic women compared with NHW women. The results of the study suggest a biologic/genetic basis for these differences.
authors.affiliation: Department of Preventive Medicine and Biometrics, University of Colorado Health Sciences Center, Denver, Colorado, USA.
authors.forename: A Tyler
authors.initials: AT
authors.lastname: Watlington
authors.forename: Tim
authors.initials: T
authors.lastname: Byers
authors.forename: Judy
authors.initials: J
authors.lastname: Mouchawar
authors.forename: Angela
authors.initials: A
authors.lastname: Sauaia
authors.forename: Jenn
authors.initials: J
authors.lastname: Ellis
mesh_terms: D000328:Adult; D001943:Breast Neoplasms / Q000175:diagnosis / Q000208:ethnology* / Q000473:pathology; D003120:Colorado; D005260:Female; D006297:Health Services Accessibility; D006801:Humans; D007348:Insurance, Health; D017058:Mexican Americans; D008875:Middle Aged; D012959:Socioeconomic Factors; D044465:White People