Mass spectrometry-based strategies for characterization of histones and their post-translational modifications.
Due to the intimate interactions between histones and DNA, the characterization of histones has become the focus of great attention. A series of mass spectrometry-based technologies have been dedicated to the characterization and quantitation of different histone forms. This review focuses on the discussion of mass spectrometry-based strategies used for the characterization of histones and their post-translational modifications.
Su
Xiaodan
X
The Ohio State Unviersity, Department of Molecular Virology Immunology & Medical Genetics, Human Cancer Genetics, Columbus, OH, USA.
Ren
Chen
C
Freitas
Michael A
MA
D006657:Histones / Q000032:analysis* / Q000737:chemistry; D013058:Mass Spectrometry / Q000379:methods*; D011499:Protein Processing, Post-Translational; D040901:Proteomics / Q000379:methods
D006657:Histones