Chemometric analysis of complex hyphenated data. Improvements of the component detection algorithm.
Component detection algorithm (CODA) is a method to quickly extract the high-quality mass chromatograms from complex liquid chromatography/electrospray ionization mass spectrometry (LC/MS) data sets, saving operators hours of analysis time. It appeared, however, that mass chromatograms with a limited baseline problem were ignored. This paper describes several methods to increase the tolerance for mass chromatograms with a baseline.
Windig
W
W
Eigenvector Research, Inc., 3905 West Eaglerock Drive, Wenatchee, WA 98801, USA. windig@eigenvector.com
Smith
W F
WF
D000465:Algorithms; D002853:Chromatography, Liquid / Q000379:methods*; D021241:Spectrometry, Mass, Electrospray Ionization / Q000379:methods*