title: Pain reduction in patients with painful vertebral compression fractures undergoing percutaneous vertebroplasty.
abstract: BACKGROUND
  Vertebral compression fracture (VCF) is the most common complication of osteoporosis. It results in significant mortality and morbidity. Percutaneous vertebroplasty (PVP) is a procedure that injects percutaneously bone cement into a collapsed vertebra.
  
  
  OBJECTIVE
  To determine the results of PVP in pain reduction from osteoporosis VCF and its complications.
  
  
  METHODS
  Thirty-five patients (34 women, 1 man, 48-98 years) with persistent back pain due to VCF underwent 66 percutaneous injection of polymethylmethacrylate (PMMA) into the vertebrae (27 thoracic levels, 39 lumbar levels) under fluoroscopic guidance between December 2003 and July 2005. Severity of back pain was assessed by using visual analog scale (VAS) before and after the operation.
  
  
  RESULTS
  Thirty-two patients (91%) reported significant pain relief the mean VAS of 35 patients, before PVP and after an 8-week period, post-operatively, were 6.9 +/-1.8 and 2.0+/-1.8 (p = 0.001). There was only one minor complication. Two patients experienced intermittent sciatic shooting pain. This improved and disappeared within three months.
  
  
  CONCLUSIONS
  P VP is a minimally invasive procedure providing safe, immediate, and sustained pain reduction in patients with refractory pain and disability caused by painful VCF
authors.affiliation: Orthopedic Division, Charoenkrung Pracharak Hospital, 8 Thanon Tok, Bangkoaleam, Bangkok 10120, Thailand. buntoengp@rcost.or.th
authors.forename: Buntoeng
authors.initials: B
authors.lastname: Pongsoipetch
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001843:Bone Cements; D005260:Female; D050815:Fractures, Compression / Q000150:complications* / Q000209:etiology / Q000628:therapy*; D006801:Humans; D007267:Injections; D008297:Male; D008875:Middle Aged; D010024:Osteoporosis / Q000150:complications; D010146:Pain / Q000209:etiology* / Q000517:prevention & control*; D019904:Polymethyl Methacrylate / Q000008:administration & dosage*; D012189:Retrospective Studies; D016103:Spinal Fractures / Q000150:complications* / Q000209:etiology / Q000628:therapy*
chemical_list: D001843:Bone Cements; D019904:Polymethyl Methacrylate