Model for spiral columns and stationary phase retention in synchronous coil planet centrifuges.
Stationary phase retention in a synchronous coil planet centrifuge or high-speed counter-current chromatography (CCC) relies on the interplay of hydrostatic (tangential and normal centrifugal) and hydrodynamic (Archimedean screw and mobile phase drag) forces. By offering a set of quantitative or semi-quantitative theoretical frameworks, this work has resolved fundamental questions such as "in the absence of mobile phase flow, how is the distribution of the two phases in a CCC column determined?" and "for Type-J CCC, do the helical and the spiral columns lead to similar performance?"
Guan
Y H
YH
Brunel Institute for Bioengineering, Brunel University West London, Uxbridge, Middlesex UB8 3PH, UK. hugh.guan@brunel.ac.uk
Fisher
D
D
Sutherland
I A
IA
D003377:Countercurrent Distribution / Q000295:instrumentation* / Q000379:methods*; D008962:Models, Theoretical