title: Rheumatoid course of humoral (vascular) rejection after heart allotransplantation.
abstract: Analysis of planned endomyocardial biopsy specimens of heart allotransplants from 22 recipients revealed signs of humoral type rejection (slight, medium, and severe) presenting as fixation of IgG, IgM, and complement components (C3, C4d) in 61 of 63 sections. Permanent presence of rejection signs attests to rheumatoid course of this process.
authors.affiliation: Institute of Transplantology and Artificial Organs, Russian Ministry of Health, Moscow.
authors.forename: L V
authors.initials: LV
authors.lastname: Beletskaya
authors.forename: A G
authors.initials: AG
authors.lastname: Kupriyanova
authors.forename: A Ya
authors.initials: AY
authors.lastname: Kormer
authors.forename: B L
authors.initials: BL
authors.lastname: Mironkov
authors.forename: E N
authors.initials: EN
authors.lastname: Kazakov
authors.forename: V I
authors.initials: VI
authors.lastname: Shumakov
mesh_terms: D000328:Adult; D001706:Biopsy; D002196:Capillaries / Q000737:chemistry / Q000276:immunology; D003176:Complement C3 / Q000276:immunology; D015935:Complement C4b / Q000276:immunology; D003331:Coronary Vessels / Q000737:chemistry / Q000276:immunology; D005260:Female; D016650:Fluorescein-5-isothiocyanate; D019085:Fluorescent Antibody Technique, Direct; D005456:Fluorescent Dyes; D006084:Graft Rejection / Q000276:immunology* / Q000473:pathology; D016027:Heart Transplantation / Q000276:immunology* / Q000473:pathology; D006801:Humans; D007074:Immunoglobulin G / Q000276:immunology; D007075:Immunoglobulin M / Q000276:immunology; D007150:Immunohistochemistry; D008297:Male; D009206:Myocardium / Q000276:immunology; D010446:Peptide Fragments / Q000276:immunology; D014184:Transplantation, Homologous
chemical_list: D003176:Complement C3; D005456:Fluorescent Dyes; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D010446:Peptide Fragments; D015935:Complement C4b; C032261:complement C4d; D016650:Fluorescein-5-isothiocyanate