A dynamically changing intracellular water network serves as a universal regulator of the cell: the water-governed cycle.
The functioning of enzymes and protein folding are well known to be assisted by the surrounding chaperoning water molecules, which are connected to the protein via non-covalent, dynamically changing chemical bonds. A molecular intracellular network of weak non-covalent connections may be presumed to exist in living cells. The roles of such non-covalent networks are examined in terms of a molecular model which postulates a universal enzyme and biochemical mechanism regulating the maintenance of chemical stability in living cells.
Szolnoki
Zoltán
Z
Department of Neurology and Neurophysiology, Pándy Kálmán County Hospital, H-5600 Békéscsaba, Pipacs köz 9, Hungary. szolnoki99@hotmail.com
D000255:Adenosine Triphosphate / Q000378:metabolism*; D000818:Animals; D001834:Body Water / Q000378:metabolism*; D002468:Cell Physiological Phenomena; D005246:Feedback / Q000502:physiology; D006706:Homeostasis / Q000502:physiology*; D006801:Humans; D008954:Models, Biological; D009097:Multienzyme Complexes / Q000378:metabolism*; D011506:Proteins / Q000378:metabolism*; D014882:Water-Electrolyte Balance / Q000502:physiology*
D009097:Multienzyme Complexes; D011506:Proteins; D000255:Adenosine Triphosphate