title: [Effect of a global intervention in the integral control of multiple risk factors in patients at high or very high cardiovascular risk. CIFARC 2 project].
abstract: OBJECTIVE
  To analyze the effect of a global approach on patients with high cardiovascular risk for the integral control of cardiovascular risk factors.
  
  
  METHODS
  Multicentric prospective study of patients with high vascular risk, followed-up for one year in internal medicine consultations. We measured the grade of control over major cardiovascular risk factors (hypertension, dyslipidemia, diabetes mellitus, tobacco, obesity) before and after the one-year follow-up period.
  
  
  RESULTS
  We studied 456 patients (56% males; age: 66.1, standard deviation: 11.5 years); 54.4% were diabetics, 58.0% had target organ damage and 46.2% had cardiovascular disease. Blood pressure control varied from 50.5 to 60.6; LDL-cholesterol control from 44.7 to 58.1%; diabetes control from 56.5 to 56.6%; tobacco control from 63.0 to 87.5% and obesity control from 60.0 to 55.4%. Integral control of all cardiovascular risk factors varied from 10.7 to 23.2% of patients. Factors independently associated to lack of integral control were: diabetes (Odds Ratio [OR]: 4.42; 95% confidence interval [95%CI]: 2.75-7.14), basal systolic blood pressure (OR: 1.03; 95%CI 1.02-1.05) and basal body mass index (OR: 1.08; 95%CI: 1.02-1.14). Lack of integral control was independently associated to the incidence of cardiovascular events (OR: 2.00; 95%CI: 1.09-5.35).
  
  
  CONCLUSIONS
  A global approach on the patient with high cardiovascular risk duplicated the integral control of the five main risk factors. Diabetes and obesity were factors which made integral control difficult. Lack of integral control increased two times the risk of cardiovascular events.
authors.affiliation: Hospital Son Llàtzer, Palma de Mallorca, España. adelapen@hsll.es
authors.forename: A
authors.initials: A
authors.lastname: de la Peña Fernández
authors.forename: B
authors.initials: B
authors.lastname: Roca Villanueva
authors.forename: I
authors.initials: I
authors.lastname: Cuende Melero
authors.forename: J R
authors.initials: JR
authors.lastname: Calabuig Alborch
authors.forename: J
authors.initials: J
authors.lastname: Montes Santiago
authors.forename: M
authors.initials: M
authors.lastname: Muñoz Rodríguez
authors.forename: M
authors.initials: M
authors.lastname: Piedracausa Selfa
authors.forename: C
authors.initials: C
authors.lastname: Suárez Fernández
mesh_terms: D000368:Aged; D002317:Cardiovascular Agents / Q000627:therapeutic use; D002318:Cardiovascular Diseases / Q000188:drug therapy / Q000453:epidemiology*; D015331:Cohort Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012307:Risk Factors; D013030:Spain / Q000453:epidemiology; D016896:Treatment Outcome
chemical_list: D002317:Cardiovascular Agents