Efficient synthesis of brussalexin A, a remarkable phytoalexin from Brussels sprouts.
The synthesis of brussalexin A, the first phytoalexin containing an allyl thiolcarbamate group, and its selective inhibitory activity against fungal plant pathogens is described.
Pedras
M Soledade C
MS
Department of Chemistry, University of Saskatchewan, 110 Science Place, Saskatoon, SK S7N 5C9, Canada. s.pedras@usask.ca
Zheng
Qing-An
QA
Sarwar
Mohammed G
MG
D000935:Antifungal Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D001937:Brassica / Q000737:chemistry*; D005658:Fungi / Q000187:drug effects / Q000254:growth & development / Q000472:pathogenicity; D007211:Indoles / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D012717:Sesquiterpenes; D013237:Stereoisomerism; D013329:Structure-Activity Relationship; D013729:Terpenes / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D013859:Thiocarbamates / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D000094162:Phytoalexins
D000935:Antifungal Agents; D007211:Indoles; D012717:Sesquiterpenes; D013729:Terpenes; D013859:Thiocarbamates; C522561:brussalexin A; D000094162:Phytoalexins