title: Flat panel detector-based volumetric computed tomography (fpVCT): performance evaluation of volumetric methods by using different phantoms in comparison to 64-multislice computed tomography.
abstract: OBJECTIVE
  Evaluation of a silicon-based flat panel volumetric computed tomography (fpVCT) and multislice CT in terms of volumetry of phantoms with different algorithms. Furthermore, to compare the different volumetric analysis methods themselves.
  
  
  METHODS
  Four phantoms of different materials have been scanned with fpVCT (GE prototype with circular gantry with 2 aSi/CsI flat panel detector) and a 64-slice spiral CT (MSCT: LightSpeed VCT). Three spherical phantoms of different materials and 1 phantom with an irregular shape were evaluated. True volumes were calculated in dependence from the diameter or by water displacement method. Imaging parameters (80 kVp, 100 mA) and the position of the phantoms were identical in both techniques. After reconstruction of the images different algorithms have been used 4 times for each phantom. These analysis methods have been performed: Region growing, threshold method, planimetry, 3-dimensional volumetry measurement by using the equation of an ellipsoid (ellipse) and an advanced lung analysis modus [single advanced lung analysis (ALA)]. The mean values and the standard deviations have been evaluated and compared with the true volumes.
  
  
  RESULTS
  In all phantoms fpVCT showed better results with lower deviations from the true values than in MSCT, especially for small volumes of the phantoms. However, the results of the ALA single method demonstrated no significant difference between the fpVCT and MSCT. The comparison of the different analysis methods revealed that 3-dimensional measurement with the ellipse method was the worst method for volume estimation, especially for the irregularly formed phantom.
  
  
  CONCLUSIONS
  fpVCT was superior to MSCT in the volumetry of small objects. The ellipse method has been shown to be the worst for volumetry with the highest relative deviations from the true volume value. The single ALA method shows the lowest standard deviation thereby revealing a reproducible volumetric method for small nodules. However, further future developments of volumetric analysis methods are necessary to use them accurately in daily routine. Due to the truly isotropic volume data set with high spatial resolution fpVCT is a powerful tool for the volumetry of small nodules.
authors.affiliation: Department of Radiology, Georg-August-University, Göttingen, Germany. soben@med.uni-goettingen.de
authors.forename: Silvia
authors.initials: S
authors.lastname: Obenauer
authors.forename: Christian
authors.initials: C
authors.lastname: Dullin
authors.forename: Markus
authors.initials: M
authors.lastname: Heuser
mesh_terms: D004867:Equipment Design; D005069:Evaluation Studies as Topic; D021621:Imaging, Three-Dimensional; D019047:Phantoms, Imaging; D011857:Radiographic Image Interpretation, Computer-Assisted / Q000295:instrumentation / Q000379:methods*; D015203:Reproducibility of Results; D036542:Tomography, Spiral Computed / Q000295:instrumentation / Q000379:methods*; D014963:X-Ray Intensifying Screens