Fungal endophthalmitis complicating subconjunctival injection of triamcinolone acetonide in anterior scleritis.
Fungal endophthalmitis following subconjunctival triamcinolone acetonide in anterior scleritis is a rare complication. Two patients with anterior scleritis, who received subconjunctival injection of triamcinolone developed fungal endophthalmitis. Both patients were positive by smear and polymerase chain reaction for 28S ribosomal RNA gene for fungus. Colletotrichum dematium was identified in one patient. Both patients responded well to pars plana vitrectomy and antifungal therapy.
Singh
Ramandeep
R
Department of Ophthalmology, Postgraduate Institute of Medical Education and Research Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Gupta
Vishali
V
Chakarborty
Arunaloke
A
Nijhawan
Raje
R
Arora
Sunil
S
Gupta
Amod
A
D000328:Adult; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage* / Q000009:adverse effects* / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use; D020231:Colletotrichum / Q000302:isolation & purification; D003228:Conjunctiva; D009877:Endophthalmitis / Q000175:diagnosis / Q000382:microbiology* / Q000601:surgery; D006801:Humans; D007267:Injections; D008297:Male; D033401:Microscopy, Acoustic; D008875:Middle Aged; D009181:Mycoses / Q000139:chemically induced* / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology; D012339:RNA, Ribosomal, 28S / Q000032:analysis; D015423:Scleritis / Q000188:drug therapy*; D014222:Triamcinolone Acetonide / Q000008:administration & dosage* / Q000009:adverse effects* / Q000627:therapeutic use; D014821:Vitrectomy
D000893:Anti-Inflammatory Agents; D000935:Antifungal Agents; D012339:RNA, Ribosomal, 28S; D014222:Triamcinolone Acetonide