title: Distortion product otoacoustic emission findings in Behçet's disease and rheumatoid arthritis.
abstract: OBJECTIVE
  This study aimed to assess cochlear functions in Behçet's disease and rheumatoid arthritis (RA) using otoacoustic emission testing (OAE), which objectively assesses outer hair cells in the cochlea.
  
  
  METHODS
  Patients with Behçet's disease (n = 16) and RA (n = 11) as well as 20 controls were tested using pure tone audiometry and transiently evoked (TEOAEs) and distortion product OAEs (DPOAEs).
  
  
  RESULTS
  Pure tone results in the Behçet's group were not significantly different from controls (p > 0.05). Pure tone results in the RA group were significantly different than in controls at 250, 500 and 6,000 Hz (p < 0.05). TEOAEs could be obtained in all participants. DPOAE amplitudes in the RA group and controls were similar (p > 0.05). DPOAE amplitudes were significantly higher in the Behçet's group than in controls at 1 and 2 kHz (p < 0.05).
  
  
  CONCLUSIONS
  A subtle deterioration in hearing can be seen at low and high frequencies in RA, which is not related to outer hair cell dysfunction as detected by DPOAE testing. In the patients with Behçet's disease who have hearing thresholds within the normal limits, outer hair cell functions seem spared with an increased activity in the apical regions of the cochlea.
authors.affiliation: Department of Otolaryngology, Faculty of Medicine, Gazi University, Ankara, Turkey. bayazity@yahoo.com
authors.forename: Yildirim A
authors.initials: YA
authors.lastname: Bayazit
authors.forename: Metin
authors.initials: M
authors.lastname: Yilmaz
authors.forename: Bulent
authors.initials: B
authors.lastname: Gunduz
authors.forename: Senay
authors.initials: S
authors.lastname: Altinyay
authors.forename: Yusuf K
authors.initials: YK
authors.lastname: Kemaloglu
authors.forename: Meltem
authors.initials: M
authors.lastname: Onder
authors.forename: Mehmet Ali
authors.initials: MA
authors.lastname: Gurer
mesh_terms: D000161:Acoustic Stimulation / Q000295:instrumentation; D000328:Adult; D001172:Arthritis, Rheumatoid / Q000453:epidemiology*; D001301:Audiometry, Pure-Tone; D001528:Behcet Syndrome / Q000453:epidemiology* / Q000503:physiopathology*; D003051:Cochlea / Q000503:physiopathology*; D005260:Female; D018072:Hair Cells, Auditory, Outer / Q000502:physiology*; D006319:Hearing Loss, Sensorineural / Q000175:diagnosis / Q000453:epidemiology / Q000503:physiopathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D017084:Otoacoustic Emissions, Spontaneous / Q000502:physiology*