title: Stability of the central visual field after modern trabeculectomy techniques in eyes with advanced glaucoma.
abstract: OBJECTIVE
  To review the surgical results and complications of trabeculectomy techniques in patients with advanced glaucoma and threatened fixation.
  
  
  METHODS
  Trabeculectomy had been carried out on 49 advanced glaucoma patients (49 eyes) using mitomycin C and postoperative laser suture lysis. The clinical records prior to and 2 months after surgery were reviewed, and the long-term surgical outcomes were determined.
  
  
  RESULTS
  Two months after surgery there were no eyes with fixation loss. Intraocular pressure (IOP) levels were reduced from 22.8 +/- 6.0 to 11.7 +/- 4.7 mmHg. Kaplan-Meier survival analysis showed that the success rate in achieving IOPs of 15 mmHg or lower 5 years after surgery was 70%. The chance of visual acuity remaining within two lines of the preoperative level was 75%. In 29 of the 49 eyes, visual acuities remained at their preoperative level at the time of the final visit, but had decreased to less than 0.1 in three eyes (cataract progression, n = 2; fixation loss, n = 1).
  
  
  CONCLUSIONS
  The results suggest that laser suture lysis and stepwise management of IOP levels, which are performed as part of the modern postoperative management of trabeculectomy, decrease the frequency of fixation loss during the early postsurgical phase.
authors.affiliation: Department of Ophthalmology and Visual Science, Kumamoto University Graduate School of Medical Sciences, Kumamoto, Japan. hirotakeawai@adelphia.net
authors.forename: Maiko
authors.initials: M
authors.lastname: Awai
authors.forename: Takahisa
authors.initials: T
authors.lastname: Koga
authors.forename: Masaru
authors.initials: M
authors.lastname: Inatani
authors.forename: Toshihiro
authors.initials: T
authors.lastname: Inoue
authors.forename: Hidenobu
authors.initials: H
authors.lastname: Tanihara
mesh_terms: D000368:Aged; D000477:Alkylating Agents / Q000008:administration & dosage*; D005260:Female; D005901:Glaucoma / Q000188:drug therapy* / Q000503:physiopathology / Q000601:surgery*; D006801:Humans; D007429:Intraocular Pressure; D008297:Male; D016685:Mitomycin / Q000008:administration & dosage*; D011183:Postoperative Complications; D011379:Prognosis; D012189:Retrospective Studies; D014130:Trabeculectomy / Q000379:methods*; D014792:Visual Acuity / Q000502:physiology; D058609:Visual Field Tests; D014794:Visual Fields / Q000502:physiology*
chemical_list: D000477:Alkylating Agents; D016685:Mitomycin