An efficient oxidative lactonization of 1,4-diols catalyzed by Cp*Ru(PN) complexes.
[reaction: see text] An efficient oxidative lactonization of 1,4-diols in acetone is accomplished by the well-defined ruthenium catalyst, whose bifunctional nature underlies the high efficiency as well as unique chemo- and regioselectivity of the reaction which provides a rapid access to gamma-butyrolactones including flavor lactones hinokinin, and muricatacin.
Ito
Masato
M
Department of Applied Chemistry, Graduate School of Science and Engineering, Tokyo Institute of Technology, 2-12-1 O-okayama, Meguro-ku, Tokyo 152-8552, Japan.
Osaku
Akihide
A
Shiibashi
Akira
A
Ikariya
Takao
T
D002384:Catalysis; D007783:Lactones / Q000737:chemistry*; D008024:Ligands; D015394:Molecular Structure; D010084:Oxidation-Reduction; D012428:Ruthenium / Q000737:chemistry*
D007783:Lactones; D008024:Ligands; D012428:Ruthenium