Acute myocardial infarction following sildenafil intake in a nitrate-free patient without previous history of coronary artery disease.
OBJECTIVE
To report the occurrence of acute myocardial infarction (MI) associated with the intake of oral sildenafil (Viagra) in a nitrate-free patient without previous history of coronary artery disease.


METHODS
A 50-year-old manual laborer was admitted to the hospital with acute inferoposterior wall MI occurring approximately 30 min after taking oral sildenafil 50 mg. This occurred before any attempted sexual activity. Subsequent angiography showed a 70% stenotic lesion in the midsegment of the dominant circumflex artery. The Naranjo scale indicated that sildenafil was a probable cause of MI.


CONCLUSIONS
This report shows a rare sildenafil-associated MI in a nitrate-free patient without a previous history of coronary artery disease.
Hayat
S
S
Department of Medicine, Mubarak Al-Kabeer Hospital, Kuwait. ht_sawsan@hotmail.com
Al-Mutairy
M
M
Zubaid
M
M
Suresh
C
C
D004562:Electrocardiography; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000139:chemically induced*; D010726:Phosphodiesterase Inhibitors / Q000009:adverse effects*; D010879:Piperazines / Q000009:adverse effects*; D011687:Purines / Q000009:adverse effects; D000068677:Sildenafil Citrate; D013450:Sulfones / Q000009:adverse effects*
D010726:Phosphodiesterase Inhibitors; D010879:Piperazines; D011687:Purines; D013450:Sulfones; D000068677:Sildenafil Citrate