title: Erosive arthropathy: clinical variance in lupus erythematosus and association with anti-CCP case series and review of the literature.
abstract: OBJECTIVE
  To describe the occurrence of erosive arthropathy in systemic lupus erythematosus (SLE) and its relationship to anti-CCP antibodies.
  
  
  METHODS
  Retrospective medical record review of a case series of five female patients with SLE and erosive arthropathies.
  
  
  RESULTS
  The initial disease presentation in all patients was a polyarthritis. Anti-CCP antibodies were detected in 4 out of 5 (80%) patients, 2 of whom had a positive rheumatoid factor.
  
  
  CONCLUSIONS
  Erosive arthritis was strongly associated with the presence of anti-CCP antibodies in these patients with SLE, who presented with polyarthritis. Anti-CCP in patients with SLE may be a marker of a more severe joint disease.
authors.affiliation: Internal Medicine and Rheumatology, National University of Colombia, Bogota, Colombia.
authors.forename: J B
authors.initials: JB
authors.lastname: Martinez
authors.forename: J S
authors.initials: JS
authors.lastname: Valero
authors.forename: A J
authors.initials: AJ
authors.lastname: Bautista
authors.forename: J F
authors.initials: JF
authors.lastname: Restrepo
authors.forename: E L
authors.initials: EL
authors.lastname: Matteson
authors.forename: F
authors.initials: F
authors.lastname: Rondon
authors.forename: A
authors.initials: A
authors.lastname: Iglesias-Gamarra
mesh_terms: D000328:Adult; D001172:Arthritis, Rheumatoid / Q000150:complications* / Q000276:immunology; D005260:Female; D050823:Hand Joints / Q000473:pathology*; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications* / Q000276:immunology; D008875:Middle Aged; D010456:Peptides, Cyclic / Q000276:immunology*; D010996:Pleural Effusion / Q000209:etiology; D012217:Rheumatoid Factor / Q000097:blood
chemical_list: D010456:Peptides, Cyclic; C487763:cyclic citrullinated peptide; D012217:Rheumatoid Factor