The role of donor and recipient in tissue implantation.
The relationships between embryonic stem and cambial cells in the ontogeny were evaluated on the basis of our data on organ embryogenesis and in vivo implantation of epithelial tissues and published data. We demonstrated the role of recipient tissues in the implantation process. Aseptic inflammation developing in response to the implant activates proliferation of the adjacent donor tissues. Proliferation and differentiation of the implanted donor tissues correspond to inflammation phases in the focus of implantation, are regulated by factors of the recipient organism, and are histogenetically determined.
Khlystova
Z S
ZS
Laboratory of Embryonic Histogenesis, Institute of Human Morphology, Russian Academy of Medial Sciences, Moscow.
Shmeleva
S P
SP
D018929:Cell Culture Techniques; D004847:Epithelial Cells / Q000166:cytology / Q000502:physiology; D006801:Humans; D007249:Inflammation / Q000473:pathology; D014019:Tissue Donors; D016378:Tissue Transplantation / Q000473:pathology / Q000502:physiology*; D014184:Transplantation, Homologous / Q000502:physiology*