title: [Malignant neoplasm of nose and paranasal sinuses in Lower Silesia in years 1992-2001].
abstract: Malignant neoplasms of the nose and paranasal sinuses occur rarely but due to late diagnosis and poor treatment effects still remain a serious problem. The aim of the study was the analysis of all nose and paranasal sinus neoplasms treated at Lower Silesia in the years 1992-2001.
  
  
  METHODS
  In the years 1992-2001 in Lower Silesia region there were 182 patients treated for malignant nose and paranasal sinus tumors. Males outnumbered females significantly with male : female ratio was 1.9:1. Principal management was combined therapy--surgery with radiotherapy in 84% of the cases. Radiotherapy alone was performed in 8.8% and chemotherapy as palliative treatment in 7.1%. Fifteen patients (8.2%) underwent radical neck dissection followed by radiotherapy.
  
  
  RESULTS
  The analysed group constituted 79.6% patients with epithelial tumors and 20.4% with nonepithelial tumors. Cases T3-T4 predominated in the material in amount of 77.9% (113). There were 15 T2 cases (10.4%) and none of T1. Most of the tumors (57%) arose from middle segment of ethmomaxillary sinuses. Upper segment tumors constituted 18.6% of cases and lower segment--10.4%. Enlarged lymph nodes were diagnosed in 8.2%. Survival rate analysis in patient treated in the years 1992-2001 revealed 37.9% (69) of 3-year survival and 30.2% (55) of 5-year survival.
  
  
  CONCLUSIONS
  Unsatisfactory results of treatment are an effect of a high advanced stage of the tumor while diagnosed. Its direct causes are: asymptomatic course of the disease, localization in complex anatomical structure, not enough experience among medical staff dealing with the disease very rarely.
authors.affiliation: Katedry i Kliniki Otolaryngologii, Akademii Medycznej we Wrocławiu.
authors.forename: Krzysztof
authors.initials: K
authors.lastname: Preś
authors.forename: Lucyna
authors.initials: L
authors.lastname: Pośpiech
authors.forename: Tomasz
authors.initials: T
authors.lastname: Krecicki
authors.forename: Beata
authors.initials: B
authors.lastname: Nadolska
authors.forename: Marzena
authors.initials: M
authors.lastname: Kubacka
authors.forename: Tomasz
authors.initials: T
authors.lastname: Zatoński
authors.forename: Agnieszka
authors.initials: A
authors.lastname: Jabłonka
authors.forename: Dorota
authors.initials: D
authors.lastname: Piechnik-Resler
authors.forename: Alina
authors.initials: A
authors.lastname: Jankowska-Konsur
mesh_terms: D002294:Carcinoma, Squamous Cell / Q000453:epidemiology* / Q000473:pathology / Q000556:secondary / Q000628:therapy*; D018572:Disease-Free Survival; D005260:Female; D006801:Humans; D008207:Lymphatic Metastasis; D008297:Male; D009367:Neoplasm Staging / Q000145:classification; D009666:Nose; D009669:Nose Neoplasms / Q000453:epidemiology* / Q000473:pathology / Q000628:therapy*; D010255:Paranasal Sinus Neoplasms / Q000453:epidemiology* / Q000473:pathology / Q000628:therapy*; D011044:Poland / Q000453:epidemiology; D018714:Radiotherapy, Adjuvant; D012189:Retrospective Studies; D017678:Sex Distribution; D015996:Survival Rate