title: Lawsonia intracellularis proliferative enteropathy in a foal.
abstract: A weanling foal was diagnosed with proliferative enteropathy caused by Lawsonia intracellularis based on history, clinical findings of depression, anorexia, weight loss, colic, diarrhea, and ventral edema, and a combination of serology and fecal PCR. An epidemiological investigation on the premises revealed that many of the other foals and adult horses were seropositive for L. intracellularis, despite being clinically normal, and identified a dog as a potential carrier and source of infection for the foal. The foal was successfully treated with a combination of azithromycin and rifampin.
authors.affiliation: Veterinary Medical Teaching Hospital, School of Veterinary Medicine, University of California, Davis, CA, USA.
authors.forename: D J
authors.initials: DJ
authors.lastname: Feary
authors.forename: C J
authors.initials: CJ
authors.lastname: Gebhart
authors.forename: N
authors.initials: N
authors.lastname: Pusterla
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D017963:Azithromycin / Q000008:administration & dosage; D002140:California / Q000453:epidemiology; D002417:Cattle; D045824:Desulfovibrionaceae Infections / Q000175:diagnosis / Q000453:epidemiology / Q000503:physiopathology / Q000662:veterinary*; D004285:Dogs; D005243:Feces / Q000382:microbiology; D005260:Female; D006734:Horse Diseases / Q000175:diagnosis* / Q000188:drug therapy / Q000453:epidemiology / Q000503:physiopathology; D006736:Horses; D020639:Lawsonia Bacteria / Q000302:isolation & purification* / Q000472:pathogenicity; D016133:Polymerase Chain Reaction / Q000662:veterinary; D012293:Rifampin / Q000008:administration & dosage; D013552:Swine; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents; D017963:Azithromycin; D012293:Rifampin