Brief report: sleep in children with sickle cell disease: an analysis of daily diaries utilizing multilevel models.
OBJECTIVE
To investigate the pain-sleep relationship in children with sickle cell disease (SCD) and the influence of stress and pain medication use on this relationship.


METHODS
Children with SCD (n = 20; aged 8-12 years) completed daily diaries assessing sleep, pain, stress, and pain medication use for up to 2 months. Data analyzed using multilevel modeling.


RESULTS
High daily pain was related to poor sleep quality that night and poor sleep quality was related to high pain the following day. High stress was related to less sleep. High same-day pain and pain medication attenuated the impact of pain on sleep quality.


CONCLUSIONS
Results highlight the importance of sleep in addressing functioning in children with chronic pain, knowledge which may help patients and their families better manage the child's pain. Behavioral pain interventions may be improved by the inclusion of strategies to encourage proper sleep hygiene and address sleep issues.
Valrie
Cecelia R
CR
The University of North Carolina at Chapel Hill, NC, USA. valriec@ecu.edu
Gil
Karen M
KM
Redding-Lallinger
Rupa
R
Daeschner
Charles
C
D000700:Analgesics / Q000627:therapeutic use; D000755:Anemia, Sickle Cell / Q000453:epidemiology* / Q000523:psychology*; D002648:Child; D004282:Documentation / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D010146:Pain / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology*; D010147:Pain Measurement; D012720:Severity of Illness Index; D012893:Sleep Wake Disorders / Q000453:epidemiology*; D011795:Surveys and Questionnaires; D013997:Time Factors
D000700:Analgesics