title: [Comparative study of maintenance of patency of triple lumen central venous catheter].
abstract: OBJECTIVE
  Establish an action protocol for the maintenance of patency of the three lumen central venous catheters (CVC) when any of them are not used. The main variable of interest was evaluate it 24 hours.
  
  
  METHODS
  This is a blind, randomized clinical trial. Phase 1: Comparison of efficacy, for maintenance of patency of the lumen at 24 hours and on discharge of the patient, of sodium heparin 500 IU (control 1), versus sodium heparin 100 IU (study 1). Phase 2: Once efficacy of sodium heparin 100 IU (control 2) was confirmed, we compared it with saline solution (SS) (study 2).
  
  
  METHODS
  multiple diseased patients admitted to eight critical care unit who were carriers of 3 lumen CVC without previous coagulation disorders.
  
  
  METHODS
  quantitative variables with mean (SD) analyzed with Student's t test and qualitative ones with -2.
  
  
  METHODS
  SPSS 12.0 program.
  
  
  RESULTS
  Phase 1: 128 catheters (control 1: 49, study 1: 79). Mean days of permanency with CVC: 5.4 (SD 6). At 24h, 100% of the CVC of both groups were patent. On discharge of the patient (n = 107) were not patent and 4.9% of the control group and 4.5% of the study group 1. Phase 2: 95 catheters (control 2: 38, study 2: 57) Mean days of permanency: 4.87 (SD 5). At 24h (n = 95), at 72 h (n = 66) and on discharge (n = 43), 100% of the CVC of both groups were patent. No significant difference was established in the two study phases between the groups studied with days of permanence, laboratory values and anticoagulant treatment.
  
  
  CONCLUSIONS
  SS is as effective as 100 or 500 IU of heparin for maintenance of patency of CVC.
authors.affiliation: Departamento de Enfermería, Universidad de Girona, España. concepcio.fuentes@udg.es
authors.forename: C
authors.initials: C
authors.lastname: Fuentes i Pumarola
authors.forename: R
authors.initials: R
authors.lastname: Casademont Mercader
authors.forename: M
authors.initials: M
authors.lastname: Colomer Plana
authors.forename: C
authors.initials: C
authors.lastname: Cordón Bueno
authors.forename: S
authors.initials: S
authors.lastname: Sabench Casellas
authors.forename: M
authors.initials: M
authors.lastname: Félez Vidal
authors.forename: E
authors.initials: E
authors.lastname: Rodríguez Plazas
mesh_terms: D000925:Anticoagulants / Q000008:administration & dosage*; D002405:Catheterization, Central Venous / Q000592:standards; D002985:Clinical Protocols; D003422:Critical Care; D003627:Data Interpretation, Statistical; D006493:Heparin / Q000008:administration & dosage*; D006801:Humans; D007362:Intensive Care Units; D012965:Sodium Chloride / Q000008:administration & dosage; D013997:Time Factors
chemical_list: D000925:Anticoagulants; D012965:Sodium Chloride; D006493:Heparin