title: Postoperative complications and functional results after subtotal gastrectomy with Billroth II reconstruction for primary gastric cancer.
abstract: Subtotal gastrectomy is considered the preferred treatment for gastric cancer with antral location. The aim of this study was to assess the incidence of early postoperative complications and late functional results in patients who underwent subtotal gastrectomy with Billroth II reconstruction for primary gastric adenocarcinoma. The results of 310 patients were analyzed with regard to postoperative complications and death rates. Functional results as they relate to the gastric resection were evaluated in 195 disease-free patients. Of the 310 patients, 77 developed postoperative general and surgical complications (24.8%) and 13 consequently died (in-hospital mortality: 4.2%). Although infrequent (6 cases, 1.9%), anastomotic leak was the most serious complication (4 cases died during the postoperative phase). Considering functional results, weight loss continued for the first trimester after surgery, after which it stabilized. Loss of appetite was rarely observed; early after the operation the majority of patients were consuming a normal diet and regularly consumed less than five meals per day (83.6%). Dumping syndrome was uncommon and usually resolved within one year (12.3% at three months, 9.5% after one year, 5.2% after two years). On the other hand, postprandial abdominal fullness was frequently observed (43.1% at three months, 36.1% after one year, 21.3% after three years, and 16.5% after five years). Billroth II reconstruction after subtotal gastrectomy is associated with a limited risk of anastomotic complications. Anastomotic leak, although infrequent, is a life-threatening complaint and requires prompt recognition and aggressive surgical treatment. The incidence of late complications was low and the majority of patients recovered from them within one year after surgery, although the occurrence of postprandial abdominal fullness was not completely irrelevant.
authors.affiliation: Department of Human Pathology and Oncology, Unit of Surgical Oncology, University of Siena, Siena, Italy.
authors.forename: Corrado
authors.initials: C
authors.lastname: Pedrazzani
authors.forename: Daniele
authors.initials: D
authors.lastname: Marrelli
authors.forename: Bernardino
authors.initials: B
authors.lastname: Rampone
authors.forename: Alfonso
authors.initials: A
authors.lastname: De Stefano
authors.forename: Giovanni
authors.initials: G
authors.lastname: Corso
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Fotia
authors.forename: Enrico
authors.initials: E
authors.lastname: Pinto
authors.forename: Franco
authors.initials: F
authors.lastname: Roviello
mesh_terms: D000230:Adenocarcinoma / Q000401:mortality / Q000601:surgery*; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001066:Appetite; D004377:Dumping Syndrome / Q000209:etiology; D005260:Female; D005743:Gastrectomy; D005763:Gastroenterostomy; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D013274:Stomach Neoplasms / Q000401:mortality / Q000601:surgery*