Performance of a rapid assay (Binax NOW) for detection of respiratory syncytial virus at a children's hospital over a 3-year period.
A rapid assay, Binax NOW RSV, was compared to viral culture for 14,756 pediatric respiratory specimens obtained from 2003 to 2006. There were 794 viral culture-confirmed respiratory syncytial virus infections. Sensitivity was 81%, and specificity was 93.2%. Sensitivity was greatest for neonates (91.1% versus 80.7% [P < 0.01]).
Cruz
Andrea T
AT
Section of Emergency Medicine, Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA. atcruz@texaschildrenshospital.org
Cazacu
Andreea C
AC
Greer
Jewel M
JM
Demmler
Gail J
GJ
D000293:Adolescent; D000328:Adult; D000956:Antigens, Viral / Q000032:analysis*; D002460:Cell Line; D002648:Child; D002675:Child, Preschool; D002845:Chromatography / Q000379:methods; D006776:Hospitals, Pediatric; D006801:Humans; D007159:Immunologic Tests / Q000379:methods; D007223:Infant; D007231:Infant, Newborn; D011933:Reagent Kits, Diagnostic; D018357:Respiratory Syncytial Virus Infections / Q000175:diagnosis* / Q000821:virology; D018113:Respiratory Syncytial Virus, Human / Q000276:immunology / Q000302:isolation & purification*; D012137:Respiratory System / Q000821:virology; D012680:Sensitivity and Specificity; D013997:Time Factors; D014776:Virus Cultivation
D000956:Antigens, Viral; D011933:Reagent Kits, Diagnostic