title: The effect of the plasma needle on tumoral cell lines apoptosis.
abstract: In this paper, we present the effect of the plasma needle on tumor cell surface. The plasma is generated at the tip of a metal needle by using a radio-frequency generator of 13.56 MHz, 100's V amplitude. In our study we investigated the interaction of non-thermal plasma (plasma needle) with living monolayer tumour cells in culture medium. We applied short needle to sample distance (1 mm) at temperature of 25 degrees C, 30 degrees C and 37 degrees C, respectively. Our data sugest that the plasma needle reduces the viability and induces apoptosis of tumour cells. These activities may be very useful in dermatology, where a part of the tissue must be removed with high-precision, without damage to the adjacent cells and without inflammatory reaction.
authors.affiliation: N.I.R.D.M.I. "Cantacuzino", Immunomodulation Department, Bucharest, Romania.
authors.forename: Ana
authors.initials: A
authors.lastname: Calugaru
authors.forename: Lidia
authors.initials: L
authors.lastname: Cremer
authors.forename: Aurora
authors.initials: A
authors.lastname: Herold
authors.forename: Andreea
authors.initials: A
authors.lastname: Lupu
authors.forename: G
authors.initials: G
authors.lastname: Szegli
authors.forename: C
authors.initials: C
authors.lastname: Lungu
authors.forename: Ana
authors.initials: A
authors.lastname: Lungu
authors.forename: N
authors.initials: N
authors.lastname: Georgescu
mesh_terms: D000818:Animals; D017209:Apoptosis; D045744:Cell Line, Tumor; D002470:Cell Survival; D003880:Dermatology / Q000379:methods; D005740:Gases; D006801:Humans; D009339:Needles
chemical_list: D005740:Gases