Supramolecular polymers based on the quadruplex formation of ditopic guanosine macromonomers in nonaqueous media.
The formation of supramolecular polymeric aggregates with a molecular mass of 100 kDa in a nonaqueous solution from a telechelic dimer of isopropylidene guanosine in the presence of K(+) ions is reported. The possible structure of macromonomers resulting from the development of G4 quartets was deduced from DOSY NMR, circular dichroism spectra, and dynamic light scattering measurements.
Pintér
Gabor
G
Department of Pharmaceutical Chemistry, University of Debrecen and Research Group for Chemistry of Antibiotics of the Hungarian Academy of Sciences, Debrecen, Hungary.
Batta
Gyula
G
Horvath
Pal
P
Löki
Istvan
I
Kurtan
Tibor
T
Antus
Sandor
S
Kéki
Sandor
S
Zsuga
Miklós
M
Nagy
Gabor
G
Aradi
Janos
J
Gunda
Tamas
T
Herczegh
Pal
P
D006151:Guanosine / Q000031:analogs & derivatives* / Q000737:chemistry; D015394:Molecular Structure; D008970:Molecular Weight; D011108:Polymers / Q000737:chemistry*; D011188:Potassium / Q000737:chemistry*
C427043:2',3'-isopropylideneguanosine; D011108:Polymers; D006151:Guanosine; D011188:Potassium