Decrease in prevalence of peptic ulcer and gastric adenocarcinoma at the Policlínico Peruano Japones, Lima, Peru, between the years 1985 and 2002. Analysis of 31,446 patients.
OBJECTIVE
To determine the prevalence of peptic ulcer and gastric adenocarcinoma in a population of middle and high socio-economic status in Lima, Peru, between 1985 and 2002.


METHODS
The prevalence of gastroduodenal ulcer and gastric adenocarcinoma was determined after studying by esophagogastroduodenoscopy 31,446 patients at the Policlínico Peruano Japonds (PPJ) between 1985 and 2002. All patients had chronic upper gastrointestinal symptoms and had endoscopically proven diagnosis of active peptic ulcer or histological diagnosis of gastric adenocarcinoma.


RESULTS
Analysis of PPJ population identified a decrease in the prevalence of gastric ulcer and duodenal ulcer from 3.15% and 5.05% respectively in 1985, to 1.62% and 2.00% respectively in 2002. Gastric adenocarcinoma prevalence also decreased from 3.19% in 1988 to 0.92% in 2002. The prevalences of gastric ulcer (OR = 1.49, 95% IC 1.26-1.77, p < 0.001), duodenal ulcer (OR = 1.32, 95% IC 1.15-1.51, p < 0.001) and gastric adenocarcinoma (OR = 1.53, 95% IC 1.25-1.86, p < 0.001), decreased in the last eight years.


CONCLUSIONS
Over the study period, there was a significant decrease in the prevalence of peptic ulcer and gastric adenocarcinoma at the Policlinico Peruano Japonés, where patients from middle and high socio economic status are attended.
Ramírez-Ramos
Alberto
A
Universidad Peruana Cayetano Heredia, Lima, Perú. ramirezramosicaza@yahoo.com
Watanabe-Yamamoto
José
J
Takano-Morón
Juan
J
Gilman
Robert H
RH
Recavarren Arce
Sixto
S
Arias-Stella
Javier
J
Yoshiwara-Wakabayashi
Elena
E
Rodríguez-Ulloa
Carlos
C
Miyagui-Maeda
Juan
J
Chinga-Alayo
Erick
E
Mendoza-Requena
Daniel
D
Leey-Casella
Julio
J
Rosas-Aguirre
Angel
A
Velapatiño-Cochachi
Billie
B
Guerra Valencia
Daniel
D
D000230:Adenocarcinoma / Q000175:diagnosis / Q000453:epidemiology*; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003430:Cross-Sectional Studies; D004381:Duodenal Ulcer / Q000453:epidemiology; D016145:Endoscopy, Digestive System; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010437:Peptic Ulcer / Q000175:diagnosis / Q000453:epidemiology*; D010568:Peru / Q000453:epidemiology; D015995:Prevalence; D017678:Sex Distribution; D012923:Social Class; D013274:Stomach Neoplasms / Q000175:diagnosis / Q000453:epidemiology*; D013276:Stomach Ulcer / Q000175:diagnosis / Q000453:epidemiology