Oxidative stress and bovine liver diseases: role of glutathione peroxidase and glucose 6-phosphate dehydrogenase.
This article summarizes the different types of free radicals, antioxidants and the effect of oxidative stress on the activities of glutathione peroxidase and glucose 6-phosphate dehydrogenase in bovine liver diseases. A growing body of evidence suggests that the formation of reactive oxygen species is a common occurrence associated with most if not all disease processes. The overall importance of reactive oxygen species to the progression and severity of various disease states varies greatly depending on the conditions and whether the disease is acute or chronic. Free radical researches in animals are in progress and further investigations are needed to establish the involvement of reactive oxygen species in diseases affecting different animal species and the pathology they produce.
Abd Ellah
Mahmoud Rushdi
MR
Department of Veterinary Medicine, Veterinary Teaching Hospital, Faculty of Agriculture, Iwate University, Ueda 3-18-8, Morioka 020-8550, Japan.
Okada
Keiji
K
Yasuda
Jun
J
D000818:Animals; D002417:Cattle; D002418:Cattle Diseases / Q000201:enzymology*; D005954:Glucosephosphate Dehydrogenase / Q000378:metabolism*; D005979:Glutathione Peroxidase / Q000378:metabolism*; D008107:Liver Diseases / Q000201:enzymology* / Q000662:veterinary*; D018384:Oxidative Stress; D010088:Oxidoreductases / Q000378:metabolism; D017382:Reactive Oxygen Species / Q000378:metabolism
D017382:Reactive Oxygen Species; D010088:Oxidoreductases; D005954:Glucosephosphate Dehydrogenase; D005979:Glutathione Peroxidase; C064258:free radical reductase