Rheumatoid course of humoral (vascular) rejection after heart allotransplantation.
Analysis of planned endomyocardial biopsy specimens of heart allotransplants from 22 recipients revealed signs of humoral type rejection (slight, medium, and severe) presenting as fixation of IgG, IgM, and complement components (C3, C4d) in 61 of 63 sections. Permanent presence of rejection signs attests to rheumatoid course of this process.
Beletskaya
L V
LV
Institute of Transplantology and Artificial Organs, Russian Ministry of Health, Moscow.
Kupriyanova
A G
AG
Kormer
A Ya
AY
Mironkov
B L
BL
Kazakov
E N
EN
Shumakov
V I
VI
D000328:Adult; D001706:Biopsy; D002196:Capillaries / Q000737:chemistry / Q000276:immunology; D003176:Complement C3 / Q000276:immunology; D015935:Complement C4b / Q000276:immunology; D003331:Coronary Vessels / Q000737:chemistry / Q000276:immunology; D005260:Female; D016650:Fluorescein-5-isothiocyanate; D019085:Fluorescent Antibody Technique, Direct; D005456:Fluorescent Dyes; D006084:Graft Rejection / Q000276:immunology* / Q000473:pathology; D016027:Heart Transplantation / Q000276:immunology* / Q000473:pathology; D006801:Humans; D007074:Immunoglobulin G / Q000276:immunology; D007075:Immunoglobulin M / Q000276:immunology; D007150:Immunohistochemistry; D008297:Male; D009206:Myocardium / Q000276:immunology; D010446:Peptide Fragments / Q000276:immunology; D014184:Transplantation, Homologous
D003176:Complement C3; D005456:Fluorescent Dyes; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D010446:Peptide Fragments; D015935:Complement C4b; C032261:complement C4d; D016650:Fluorescein-5-isothiocyanate