title: Wall-eyed bilateral internuclear ophthalmoplegia from lesions at different levels in the brainstem.
abstract: Wall-eyed bilateral internuclear ophthalmoplegia (WEBINO) is a rarely reported syndrome. There is dispute about whether WEBINO is caused by a pontine or a midbrain lesion and whether the medial rectus subnuclei are implicated. In a study of the clinical and imaging features of four patients with WEBINO, we found that that three of four lesions involved the midbrain but not necessarily the medial rectus subnuclei.
authors.affiliation: Section of Neurology, Department of Internal Medicine, Feng Yuan Hospital, Department of Health, Executive Yuan, Taiwan, Republic of China. jmchen@mail.fyh.doh.gov.tw
authors.forename: Chien-Ming
authors.initials: CM
authors.lastname: Chen
authors.forename: Sung-Hsiung
authors.initials: SH
authors.lastname: Lin
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002545:Brain Ischemia / Q000150:complications* / Q000175:diagnosis; D001933:Brain Stem; D003937:Diagnosis, Differential; D005133:Eye Movements; D017809:Fatal Outcome; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D015835:Ocular Motility Disorders / Q000175:diagnosis / Q000209:etiology* / Q000503:physiopathology; D009801:Oculomotor Muscles / Q000503:physiopathology; D014057:Tomography, X-Ray Computed