Adaptation of a quantitative trait to a moving optimum.
We investigate adaptive evolution of a quantitative trait under stabilizing selection with a moving optimum. We characterize three regimes, depending on whether (1) the beneficial mutation rate, (2) the fixation time, or (3) the rate of environmental change is the limiting factor for adaptation. If the environment is rate limiting, mutations with a small phenotypic effect are preferred over large mutations, in contrast to standard theory.
Kopp
Michael
M
Section of Evolutionary Biology, Department Biology II, Ludwig-Maximilian-University, Munich, Germany. kopp@zi.biologie.uni-muenchen.de
Hermisson
Joachim
J
D000483:Alleles; D000818:Animals; D005075:Biological Evolution; D003198:Computer Simulation; D008957:Models, Genetic; D016296:Mutagenesis / Q000235:genetics; D019655:Quantitative Trait, Heritable; D012641:Selection, Genetic