title: Focale: study of systolic and diastolic heart failure in a French elderly population.
abstract: BACKGROUND
  The epidemic of heart failure (HF) in France has not been fully investigated and data on both the systolic and diastolic forms are limited.
  
  
  OBJECTIVE
  To determine the prevalence, aetiology and treatments of both forms in French patients over 65 with HF (NYHA grade II-IV).
  
  
  METHODS
  Cross-sectional study of 446 patients with HF recruited by 273 randomly selected cardiologists in France, with echocardiography and ECG available for central reading.
  
  
  METHODS
  Prevalence of diastolic (DHF) and systolic (SHF) HF using the left ventricular ejection fraction (LVEF).
  
  
  RESULTS
  DHF, with a mean LVEF of 57.6+/-8.0%, was reported for 245 (54.9%) patients and SHF, with a mean LVEF of 33.33+/-8.0% was reported for 201 (45.1%) patients. Men were more prone to suffer SHF than DHF whereas for women the reverse was true. As compared to SHF, DHF endsystolic and enddiastolic volumes were smaller, the thickness/radius ratio was greater, with a longer E-wave deceleration time and a shorter peak filling rate. Aetiology and treatments were similar in both types of HF, except for ACE inhibitors and aldosterone antagonists, which were more frequently prescribed in SHF.
  
  
  CONCLUSIONS
  This observational study provides further knowledge of SHF and DHF in outpatients.
authors.affiliation: Hôpital Ambroise Paré, AP-HP Boulogne-Billancourt, Université de Versailles-Saint Quentin en Yvelines, France. olivier.dubourg@apr.aphp.fr
authors.forename: Olivier
authors.initials: O
authors.lastname: Dubourg
authors.forename: Pascal
authors.initials: P
authors.lastname: Gueret
authors.forename: Alain
authors.initials: A
authors.lastname: Beauchet
authors.forename: Sophie
authors.initials: S
authors.lastname: Nisse-Durgeat
authors.forename: Alain
authors.initials: A
authors.lastname: Ducardonnet
mesh_terms: D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D002316:Cardiotonic Agents / Q000627:therapeutic use; D003430:Cross-Sectional Studies; D003971:Diastole; D015150:Echocardiography, Doppler; D004562:Electrocardiography; D005260:Female; D005602:France / Q000453:epidemiology; D015577:Geriatric Assessment; D006333:Heart Failure / Q000175:diagnosis* / Q000188:drug therapy / Q000453:epidemiology*; D006801:Humans; D008297:Male; D011336:Probability; D011379:Prognosis; D018570:Risk Assessment; D012720:Severity of Illness Index; D017678:Sex Distribution; D018709:Statistics, Nonparametric; D013318:Stroke Volume; D016019:Survival Analysis; D013599:Systole; D018487:Ventricular Dysfunction, Left / Q000175:diagnosis* / Q000188:drug therapy / Q000453:epidemiology*
chemical_list: D002316:Cardiotonic Agents