Thirty years of kidney transplantation in two Chinese centers.
Since the first kidney transplantation was performed in 1976, 4,306 renal transplantations have been performed at Shanghai No. 1 People's Hospital and Fujian Oriental Hospital. Nearly all (99%) of the grafts were from deceased donors. Graft survival rates in the era of modern immunosuppression and HLA-based organ allocation have improved substantially. The one-, 5- and 10-year graft survival rates for 2,575 transplants performed during 1995-2004 were 93.9%, 71.8% and 53.9%, respectively. Chronic rejection accounted for 54.3% of graft failures and 54.2% of patient deaths resulted from graft failure. We performed 48 combined liver-kidney transplants since 2001 and the first simultaneous human islet-kidney transplantation last year.
Tan
Jianming
J
Renal Transplant Center, Shanghai No. 1 People's Hospital, Shanghai, PR China.
Qiu
Jianxin
J
Lu
Tieming
T
Liu
Zhihong
Z
Guo
Yifeng
Y
Zhang
Shanzhong
S
Tang
Xiaoda
X
D002102:Cadaver; D002423:Cause of Death; D002681:China; D006801:Humans; D007674:Kidney Diseases / Q000145:classification / Q000601:surgery; D016030:Kidney Transplantation / Q000276:immunology / Q000401:mortality / Q000706:statistics & numerical data*; D016031:Liver Transplantation / Q000706:statistics & numerical data; D019520:Living Donors / Q000706:statistics & numerical data; D016019:Survival Analysis; D014019:Tissue Donors / Q000706:statistics & numerical data; D017211:Treatment Failure