[Mammographic findings in microcalcifications associated with breast cancer after neoadjuvant chemotherapy].
OBJECTIVE
To evaluate the mammographic findings in microcalcifications associated with breast cancer after neoadjuvant chemotherapy.


METHODS
From January 2000 to May 2005, a total of 99 breast cancer patients underwent neoadjuvant chemotherapy. Ten patients had microcalcifications on mammograms prior to treatment. We evaluated the evolution of the tumor and of the microcalcifications, correlating the imaging findings with the clinical and histological manifestations.


RESULTS
Four different patterns of evolution were observed for the microcalcifications: the number of particles increased in two cases, remained stable in three, decreased in four, and in one patient the microcalcifications disappeared. The size of the tumor decreased in all cases.


CONCLUSIONS
After neoadjuvant chemotherapy microcalcifications can evolve unpredictably and independently of tumor response.
Noguera
J J
JJ
Servicio de Radiodiagnóstico, Clínica Universitaria de Navarra, Universidad de Navarra, Pamplona, España. jnoguera@unav.es
de Luis
E
E
Alonso-Burgos
A
A
Viteri
S
S
Zornoza
G
G
Pina
L
L
D000328:Adult; D000368:Aged; D001941:Breast Diseases / Q000000981:diagnostic imaging* / Q000209:etiology; D001943:Breast Neoplasms / Q000150:complications / Q000188:drug therapy*; D002114:Calcinosis / Q000000981:diagnostic imaging* / Q000209:etiology; D017024:Chemotherapy, Adjuvant; D005260:Female; D006801:Humans; D008327:Mammography; D008875:Middle Aged; D020360:Neoadjuvant Therapy; D012189:Retrospective Studies