title: Effectiveness of a honey dressing for healing pressure ulcers.
abstract: OBJECTIVE
  To compare the effect of a honey dressing vs an ethoxy-diaminoacridine plus nitrofurazone dressing in patients with pressure ulcers.
  
  
  METHODS
  This 5-week randomized clinical trial evaluated the effect of a honey dressing on pressure ulcer healing.
  
  
  METHODS
  Thirty-six patients with a total of 68 stage II or III pressure ulcers referred from a university hospital in Izmir were enrolled in the study. Twenty-six subjects completed the trial.
  
  
  METHODS
  Ulcers were measured with acetate tracings and Pressure Ulcer Scale for Healing (PUSH) evaluations.
  
  
  METHODS
  Fifteen patients with 25 pressure ulcers were treated with honey dressings, and 11 patients with 25 pressure ulcers were treated with ethoxy-diaminoacridine plus nitrofurazone dressings. Wound healing was assessed weekly using the PUSH tool, version 3.0. The primary outcome measure was the change in PUSH tool scores in each group at 5 weeks.
  
  
  RESULTS
  The two groups were statistically similar with regard to baseline and wound characteristics. After 5 weeks of treatment, patients who were treated by honey dressing had significantly better PUSH tool scores than subjects treated with the ethoxy-diaminoacridine plus nitrofurazone dressing (6.55 +/- 2.14 vs 12.62 +/- 2.15, P < .001).
  
  
  CONCLUSIONS
  By week 5, PUSH tool scores showed that healing among subjects using a honey dressing was approximately 4 times the rate of healing in the comparison group. The use of a honey dressing is effective and practical.
authors.affiliation: Ege University School of Nursing, Izmir/Turkey. ulku.gunes@ege.edu.tr
authors.forename: Ulkü
authors.initials: U
authors.lastname: Yapucu Güneş
authors.forename: Ismet
authors.initials: I
authors.lastname: Eşer
mesh_terms: D000368:Aged; D000585:Aminacrine / Q000627:therapeutic use; D000891:Anti-Infective Agents, Local / Q000627:therapeutic use; D001458:Bandages / Q000592:standards*; D015400:Clinical Nursing Research; D005260:Female; D006722:Honey / Q000592:standards*; D006785:Hospitals, University; D006801:Humans; D008297:Male; D008875:Middle Aged; D009583:Nitrofurazone / Q000627:therapeutic use; D009730:Nursing Assessment / Q000379:methods; D003668:Pressure Ulcer / Q000145:classification / Q000175:diagnosis / Q000517:prevention & control*; D012720:Severity of Illness Index; D017592:Skin Care / Q000379:methods* / Q000451:nursing; D016896:Treatment Outcome; D014421:Turkey; D014945:Wound Healing
chemical_list: D000891:Anti-Infective Agents, Local; D000585:Aminacrine; D009583:Nitrofurazone