title: Solitary intracranial Castleman's disease, plasma cell variant: a case report.
abstract: OBJECTIVE
  We report a case of plasma cell variant of Castleman's disease confined to the meninges.
  
  
  METHODS
  A 53-year-old woman presented with severe headache lasting a few months, which was insidious in onset but followed a progressive course with associated vomiting, blurring of vision and diplopia. Investigations revealed a dural-based mass that was considered both radiologically and intraoperatively as a meningioma. Total surgical excision of the mass was performed. Histologically, it was a plasma cell variant of Castleman's disease with kappa light chain restriction. Laboratory investigations and whole body computerized tomography scan showed no significant abnormality. A short course of local radiotherapy was given. The patient is well 2 years after treatment.
  
  
  CONCLUSIONS
  This report highlights the rarity of solitary intracranial Castleman's disease and the difficulty in radiological and intraoperative diagnosis.
authors.affiliation: Department of Pathology, Al-Sabah Hospital, Safat, Kuwait. anupamamallik@yahoo.co.in
authors.forename: A A
authors.initials: AA
authors.lastname: Mallik
authors.forename: K C
authors.initials: KC
authors.lastname: Katchy
authors.forename: N
authors.initials: N
authors.lastname: Clotan
mesh_terms: D005871:Castleman Disease / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D003131:Combined Modality Therapy; D003287:Contrast Media; D003937:Diagnosis, Differential; D004388:Dura Mater / Q000473:pathology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D014057:Tomography, X-Ray Computed
chemical_list: D003287:Contrast Media