Critical evaluation of esophageal dilation in nonobstructive dysphagia with and without esophageal rings.
OBJECTIVE
To evaluate the therapeutic efficacy of esophageal dilation compared with medical treatment in patients with nonobstructive dysphagia (NOD).


BACKGROUND
Clinical studies evaluating the role of esophageal dilation in patients with NOD have reported conflicting results. In addition, studies suggesting beneficial effects of esophageal dilation in this group of patients have not compared it with medical treatment.


METHODS
We conducted a retrospective study in 107 patients with NOD and divided these patients into 2 groups. Group 1 included patients who received esophageal dilation with a polyvinyl bougie along with adjunctive medical treatment, and group 2 included patients who received medical treatment alone.


RESULTS
Complete resolution of symptoms occurred in 41 of the 60 patients (68.3%) who received esophageal dilation. In the group that received medical treatment alone (n=47), 28 patients (59.5%) had complete resolution of symptoms. There was no statistically significant difference in symptom resolution between the 2 groups. In addition, among 22 patients with esophageal rings, 17 patients (77%) had complete symptomatic relief with dilation, as compared with 63% patients without esophageal rings. Although there was a trend towards higher frequency of dysphagia resolution with esophageal dilation in patients with NOD and esophageal rings, the difference failed to reach statistical significance.


CONCLUSIONS
Esophageal dilation and medical therapy are equally efficacious (60% to 70% of cases) in resolving symptoms of dysphagia in patients with NOD. Patients with NOD and esophageal rings may represent the subgroup of patients who are more likely to benefit from esophageal dilation.
Naini
Pranitha
P
Division of Gastroenterology, Department of Medicine, Sinai Hospital of Baltimore, Baltimore, MD 21215, USA.
Dutta
Sudhir K
SK
Karhadkar
Arati S
AS
Rengen
Mohan
M
Nanavati
Shardul
S
Arora
Manish
M
Merchant
Nipun
N
D002985:Clinical Protocols; D003680:Deglutition Disorders / Q000188:drug therapy / Q000628:therapy*; D004106:Dilatation / Q000295:instrumentation / Q000379:methods*; D005500:Follow-Up Studies; D006801:Humans; D012189:Retrospective Studies; D016896:Treatment Outcome