title: Acute renal failure due to bilateral uric acid lithiasis in infants.
abstract: Acute renal failure (ARF) is one of the complications of urolithiasis, but the role of medical treatment to relieve urinary obstruction in children with ARF is uncertain. We report on infants with acute obstructive uric acid lithiasis. We describe presentation features as well as diagnosis methods and medical treatment in five infants who were admitted to our institution with ARF due to uric acid lithiasis. The medical treatments for all patients were fluid liberalization, urine alkalinization, and oral allopurinol. Two children underwent urinary diversion. Within 8 h, urine output improved in all patients, and the stones passed spontaneously. All obstructed kidneys were relieved with medical treatment, and no renal sequel remained. So this series has showed a role of medical therapy in acute obstructive uric acid lithiasis.
authors.affiliation: Department of Pediatric Surgery, Harran University School of Medicine, Sanliurfa, Turkey. kayamete@yahoo.com
authors.forename: Mete
authors.initials: M
authors.lastname: Kaya
authors.forename: M Emin
authors.initials: ME
authors.lastname: Boleken
authors.forename: Mustafa
authors.initials: M
authors.lastname: Soran
authors.forename: Turan
authors.initials: T
authors.lastname: Kanmaz
authors.forename: Selçuk
authors.initials: S
authors.lastname: Yücesan
mesh_terms: D058186:Acute Kidney Injury / Q000175:diagnosis / Q000209:etiology*; D000493:Allopurinol / Q000627:therapeutic use; D000963:Antimetabolites / Q000627:therapeutic use; D005260:Female; D005440:Fluid Therapy / Q000379:methods; D006801:Humans; D007223:Infant; D008297:Male; D011446:Prospective Studies; D016896:Treatment Outcome; D014547:Urinary Diversion / Q000379:methods; D052878:Urolithiasis / Q000150:complications* / Q000175:diagnosis / Q000628:therapy
chemical_list: D000963:Antimetabolites; D000493:Allopurinol