title: Serum adiponectin and leptin in a patient with Cushing's syndrome before and after adrenalectomy.
abstract: We measured the serum adiponectin and leptin concentrations before and after successful removal of a left adrenal adenoma in a 46-year-old woman with Cushing's syndrome. The serum adiponectin level was 6.0 microg/ml before the operation and rose to 8.1 microg/ml after adrenalectomy. However, the serum leptin level was markedly high (24.8 ng/ml) before the operation and decreased to within the normal range (6.0 ng/ml) 6 months after adrenalectomy, concomitant with weight reduction and normalization of the serum cortisol level.
authors.affiliation: Division of Cardiovascular Medicine, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan.
authors.forename: Naoto
authors.initials: N
authors.lastname: Ashizawa
authors.forename: Mayuko
authors.initials: M
authors.lastname: Takagi
authors.forename: Shinji
authors.initials: S
authors.lastname: Seto
authors.forename: Shin
authors.initials: S
authors.lastname: Suzuki
authors.forename: Katsusuke
authors.initials: K
authors.lastname: Yano
mesh_terms: D000236:Adenoma / Q000097:blood / Q000175:diagnosis / Q000601:surgery*; D052242:Adiponectin / Q000097:blood*; D000310:Adrenal Gland Neoplasms / Q000097:blood / Q000175:diagnosis / Q000601:surgery*; D000315:Adrenalectomy / Q000379:methods; D015415:Biomarkers / Q000097:blood; D001774:Blood Chemical Analysis; D003480:Cushing Syndrome / Q000097:blood / Q000175:diagnosis / Q000601:surgery*; D005260:Female; D006801:Humans; D020738:Leptin / Q000097:blood*; D008875:Middle Aged; D011184:Postoperative Period; D011300:Preoperative Care; D012680:Sensitivity and Specificity; D016896:Treatment Outcome
chemical_list: D052242:Adiponectin; D015415:Biomarkers; D020738:Leptin