[The analysis of lipidogram parameters and the parameters of coagulation and fibrynolysis systems as risk factors in overweight and obese children and adolescents].
Since artherosclerosis processes were proved to have their origins as early as in one's childhood, attempts have been made to find the risk factors in the population of the developmental age.


OBJECTIVE
The aim of this work was the analysis of lipidogram parameters and the parameters of coagulation and fibrynolysis systems in overweight and obese children and adolescents.


METHODS
101 children and adolescents aged 4-19 were examined, including 30 overweight and 34 obese ones, with the control group comprising 37 patients with normal body weight.


RESULTS
No significant differences in the studied groups were noticed in the total cholesterol level, LDL, fibrinogen and in alpha2-antiplasmin activity. The HDL cholesterol level was actually lower in the group with obese patients, while the PAI-1 level was actually higher.


CONCLUSIONS
Overweight and obese children and adolescents comprise a group threatened by premature development of atherosclerosis and need to be monitored for risk factors.
Kuczyńska
Renata
R
Department of Children Diseases, Allergology and Gastroenterology, Nicolaus Copernicus University in Toruń, Collegium Medicum of Bydgoszcz, Poland. klped@cm.ukm.pl
Sieluzycka
Aurelia
A
Gasiorowska
Joanna
J
Grabarczyk
Ewa
E
Góralczyk
Barbara
B
Czerwionka-Szaflarska
Mieczysława
M
D000293:Adolescent; D000328:Adult; D015415:Biomarkers / Q000097:blood; D001779:Blood Coagulation Factors / Q000032:analysis*; D015992:Body Mass Index; D002648:Child; D002675:Child, Preschool; D002784:Cholesterol; D008076:Cholesterol, HDL / Q000097:blood; D008078:Cholesterol, LDL / Q000097:blood; D005260:Female; D005340:Fibrinogen; D005343:Fibrinolytic Agents / Q000097:blood*; D006801:Humans; D008055:Lipids / Q000097:blood*; D008297:Male; D009765:Obesity / Q000503:physiopathology*; D050177:Overweight / Q000502:physiology; D017395:Plasminogen Activator Inhibitor 1; D012016:Reference Values; D012044:Regression Analysis; D012307:Risk Factors; D014280:Triglycerides / Q000097:blood; D000979:alpha-2-Antiplasmin
D015415:Biomarkers; D001779:Blood Coagulation Factors; D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D005343:Fibrinolytic Agents; D008055:Lipids; D017395:Plasminogen Activator Inhibitor 1; D014280:Triglycerides; D000979:alpha-2-Antiplasmin; D005340:Fibrinogen; D002784:Cholesterol