Shp2, a novel oncogenic tyrosine phosphatase and potential therapeutic target for human leukemia.
Xu
Rongzhen
R
Department of Hematology, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, China. xurongzhen@hzcnc.com
D000970:Antineoplastic Agents / Q000627:therapeutic use; D002453:Cell Cycle; D002454:Cell Differentiation; D045744:Cell Line, Tumor; D049109:Cell Proliferation; D004789:Enzyme Activation; D006412:Hematopoietic Stem Cells / Q000502:physiology; D006801:Humans; D047908:Intracellular Signaling Peptides and Proteins / Q000037:antagonists & inhibitors / Q000235:genetics; D007938:Leukemia / Q000188:drug therapy / Q000235:genetics / Q000378:metabolism*; D009154:Mutation; D010766:Phosphorylation; D054592:Protein Tyrosine Phosphatase, Non-Receptor Type 11; D017027:Protein Tyrosine Phosphatases / Q000037:antagonists & inhibitors / Q000096:biosynthesis* / Q000235:genetics
D000970:Antineoplastic Agents; D047908:Intracellular Signaling Peptides and Proteins; C516724:PTPN11 protein, human; D054592:Protein Tyrosine Phosphatase, Non-Receptor Type 11; D017027:Protein Tyrosine Phosphatases