title: Effect of radiofrequency catheter ablation on Doppler echocardiographic parameters in patients with Wolff-Parkinson-White syndrome.
abstract: The aim of this study was to compare the conventional Doppler echocardiographic parameters before and after accessory pathway ablation in patients with Wolff-Parkinson-White (WPW) syndrome. Thirty patients (19 males, 11 females) aged 35.5 +/- 14.4 years were enrolled in the study. All patients underwent successful radiofrequency catheter ablation (RFCA). Echocardiograhic examination was performed before and after RFCA. Aortic and pulmonary flows, diastolic early (E) and late (A) transmitral filling velocities, their velocity time integrals (VTI), mitral diastolic filling time (DFT), deceleration time (DT), isovolumic relaxation time (IVRT), aortic ejection time, and aortic VTI were assessed before and after RFCA. We found that the pulmonary valve opened earlier than the aortic valve when the accessory pathway was located on the right ventricular side (P = 0.02). Otherwise, if the accessory pathway was located on the left ventricular side, the aortic valve opened earlier (P < 0.01). Intervals between the onsets of aortic and pulmonary flows were shortened after RFCA (P = 0.01). We also observed prolongation of DFT (P < 0.001), increases in A velocity (P < 0.05) and its VTI (P < 0.01), as well as a decrease in the E/A ratio (P < 0.01) and shortening of aortic ejection time (P = 0.01) with restoration of AV conduction. We conclude that Doppler echocardiographic examination can provide clues about accessory pathway location and RFCA causes some significant changes in Doppler echocardiographic time intervals. These changes confirm that cardiac synchrony is restored after RFCA.
authors.affiliation: Department of Cardiology, Siyami Ersek Thoracic and Cardiovascular Surgery Training and Research Center, Istanbul, Turkey.
authors.forename: Nazmiye
authors.initials: N
authors.lastname: Cakmak
authors.forename: Mahmut
authors.initials: M
authors.lastname: Cakmak
authors.forename: Ahmet
authors.initials: A
authors.lastname: Akyol
authors.forename: Enis
authors.initials: E
authors.lastname: Oguz
authors.forename: Nurten
authors.initials: N
authors.lastname: Sayar
authors.forename: Abdurrahman
authors.initials: A
authors.lastname: Eksik
authors.forename: Ahmet
authors.initials: A
authors.lastname: Alper
authors.forename: Hakan
authors.initials: H
authors.lastname: Hasdemir
authors.forename: Hale
authors.initials: H
authors.lastname: Yilmaz
authors.forename: Izzet
authors.initials: I
authors.lastname: Erdinler
authors.forename: Kadir
authors.initials: K
authors.lastname: Gurkan
mesh_terms: D000328:Adult; D001021:Aortic Valve / Q000000981:diagnostic imaging / Q000503:physiopathology; D001783:Blood Flow Velocity / Q000502:physiology; D017115:Catheter Ablation; D015331:Cohort Studies; D003326:Coronary Circulation / Q000502:physiology; D015150:Echocardiography, Doppler; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011664:Pulmonary Valve / Q000000981:diagnostic imaging / Q000503:physiopathology; D014927:Wolff-Parkinson-White Syndrome / Q000000981:diagnostic imaging* / Q000503:physiopathology / Q000601:surgery*