title: The incidence of motor nueron disease in Scotland.
abstract: Between 1989 and 1998, 1226 cases of ALS/MND were identified in Scotland, with mean age of onset 65.2 (SD 11.9) years for men and 67.2 (SD 11.0) for women. Annual standardized incidence was 2.40 per 100,000 (95% CI 2.22-2.58). Using capture recapture methods we confirm a high level of case ascertainment for each year of study. Incidence and ascertainment of ALS has remained stable in a large population over a prolonged period of time. Large population-based databases can be used to test aetiological hypotheses.
authors.affiliation: Department of Neurology, Ninewells Hospital and Medical School, Dundee, DD1 9SY Scotland UK.
authors.forename: Raeburn B
authors.initials: RB
authors.lastname: Forbes
authors.forename: Shuna
authors.initials: S
authors.lastname: Colville
authors.forename: John
authors.initials: J
authors.lastname: Parratt
authors.forename: Robert J
authors.initials: RJ
authors.lastname: Swingler
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D000690:Amyotrophic Lateral Sclerosis / Q000453:epidemiology; D002648:Child; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D016472:Motor Neuron Disease / Q000453:epidemiology*; D012016:Reference Values; D012606:Scotland / Q000453:epidemiology