title: Antibiotic susceptibility of bacterial isolates from corneal ulcers of dogs in Taiwan.
abstract: OBJECTIVE
  To analyse antibiotic susceptibility of bacteria associated with ulcerative keratitis in dogs.
  
  
  METHODS
  Bacteria isolated from 190 eyes with ulcerative keratitis were identified, and the antibiotic susceptibility of isolates was studied.
  
  
  RESULTS
  In total, 258 species of bacteria were isolated from the 190 eyes. Of the isolates, 78 per cent were Gram-positive and 28 per cent were Gram-negative bacteria. The most commonly isolated Gram-positive bacteria in dogs were Staphylococcus spp (49 per cent), Streptococcus spp (7 per cent) and Corynebacterium spp (7 per cent); while Pseudomonas aeruginosa (7.6 per cent) and Escherichia coli (5.8 per cent) were the commonest Gram-negative pathogens. Resistance to commonly used ophthalmic antibiotics was seen in Staphylococcus, Streptococcus, Corynebacterium, Pseudomonas and Escherichia species isolates.
  
  
  CONCLUSIONS
  Isolates from dogs with corneal ulcers in Taiwan may be resistant to several commonly used ophthalmic preparations. Ciprofloxacin showed good action against most isolates, with the notable exception of Streptococcus species. Chloramphenicol or cephalothin had the best in vitro action against the Streptococcus species isolates.
authors.affiliation: Division of Ophthalmology, Department of Veterinary Medicine, College of Bio-Resources and Agriculture, National Taiwan University, No. 1, Section 4, Roosevelt Road,Taipei 106, Taiwan.
authors.forename: C-T
authors.initials: CT
authors.lastname: Lin
authors.forename: S M
authors.initials: SM
authors.lastname: Petersen-Jones
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D015169:Colony Count, Microbial / Q000662:veterinary; D003320:Corneal Ulcer / Q000188:drug therapy / Q000382:microbiology / Q000662:veterinary*; D004283:Dog Diseases / Q000188:drug therapy / Q000382:microbiology*; D004285:Dogs; D004305:Dose-Response Relationship, Drug; D024881:Drug Resistance, Bacterial; D005260:Female; D006090:Gram-Negative Bacteria / Q000187:drug effects*; D006094:Gram-Positive Bacteria / Q000187:drug effects*; D008297:Male; D008826:Microbial Sensitivity Tests / Q000662:veterinary; D013624:Taiwan
chemical_list: D000900:Anti-Bacterial Agents