Introduction of Haemophilus influenzae type B conjugate vaccine into routine immunization in Ghana and its impact on bacterial meningitis in children younger than five years.
This report shows the impact of a pentavalent vaccine that includes Haemophilus influenzae type b (Hib) conjugate vaccine on bacterial meningitis in children younger than 5 years in Ghana. A review of the first 3 years of a pediatric bacterial meningitis surveillance program, started in August 2001 in Accra, Ghana, was undertaken. There was a significant reduction, P = 0.042 and 0.017, in percentage of purulent meningitis in children younger than 1 year, comparing the first year when the vaccine was introduced, to the second and third years, respectively.
Renner
Lorna Awo
LA
Department of Child Health, University of Ghana Medical School, Accra, Ghana. lornarenner@africaonline.com.gh
Newman
Mercy J
MJ
Ahadzie
Lawson
L
Antwi-Agyei
Kwadwo Odei
KO
Eshetu
Messeret
M
D002675:Child, Preschool; D005869:Ghana / Q000453:epidemiology; D018073:Haemophilus Vaccines / Q000008:administration & dosage* / Q000276:immunology; D019741:Haemophilus influenzae type b / Q000276:immunology* / Q000302:isolation & purification; D006801:Humans; D017589:Immunization Programs; D015994:Incidence; D007223:Infant; D016920:Meningitis, Bacterial / Q000453:epidemiology* / Q000382:microbiology / Q000517:prevention & control*; D008583:Meningitis, Haemophilus / Q000453:epidemiology / Q000382:microbiology / Q000517:prevention & control; D009345:Neisseria meningitidis / Q000302:isolation & purification; D013296:Streptococcus pneumoniae / Q000302:isolation & purification; D018074:Vaccines, Conjugate / Q000008:administration & dosage* / Q000276:immunology
D018073:Haemophilus Vaccines; D018074:Vaccines, Conjugate