Incidence of large-for-gestational age newborn: a comparison between pregnant women with abnormal and normal screening test for gestational diabetes.
OBJECTIVE
To evaluate the incidence of large-for-gestational age (LGA) newborn between pregnant women with abnormal and normal glucose challenge test (GCT).


METHODS
Retrospective cohort study.


METHODS
Two hundred and sixty pregnant women, who were at risk for gestational diabetes mellitus (GDM), received screening following practice guideline. The women were divided into two groups. The study group comprised of 130 women whose screening test results of 50-g 1-hour GCT were abnormal but had not been diagnosed with GDM (normal oral glucose tolerance test). The control group comprised of 130 women whose GCT results were normal. Comparison of various maternal and neonatal characteristics as well as the incidence of LGA between the groups was made.


RESULTS
There were no significant differences in age, gestational age at first antenatal care, body mass index, and risk of GDM between the two groups. The study group had a significantly higher number of parity and number of risk factors of GDM than the control group. There was no significant difference in the incidence of LGA newborn between the two groups (8.5% in the study group and 10.8% in the control group, p = 0.528). There were also no significant differences in gestational age at delivery, pre-eclampsia, pre-term delivery, hyperbillirubinemia of the newborn between the two groups. There were no cases of maternal acute postpartum hemorrhage, and birth asphyxia.


CONCLUSIONS
The incidence ofLGA newborn was similar between non-GDMwomen with abnormal and normal screening GCT results in Siriraj Hospital.
Luengmettakul
Jiraporn
J
Department of Obstetrics and Gynecology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkoknoi, Bangkok 10700, Thailand. nidnhoi_l@hotmail.com
Boriboonhirunsam
Dittakarn
D
Sutantawibul
Anuwat
A
Sunsaneevithayakul
Prasert
P
D000328:Adult; D015331:Cohort Studies; D016640:Diabetes, Gestational; D005260:Female; D005320:Fetal Macrosomia / Q000453:epidemiology*; D005865:Gestational Age; D006801:Humans; D015994:Incidence; D007231:Infant, Newborn; D011247:Pregnancy; D012189:Retrospective Studies