Malaria transmission-blocking vaccines: the bonus of effective malaria control.
Reduction of transmission is important for effective malaria control. Standard microscopic detection grossly underestimates the human transmission reservoir. Malaria transmission intensity is defined by local and focal conditions. Transmission-blocking vaccines may be effective by directly targeting identified hot spots of transmission.
Sauerwein
Robert W
RW
Department of Medical Microbiology, Radboud University Nijmegen Medical Centre, MMB 268, PO Box 9101, 6500 HB Nijmegen, The Netherlands. r.sauerwein@mmb.umcn.nl
D000818:Animals; D002353:Carrier State / Q000469:parasitology; D004197:Disease Reservoirs / Q000469:parasitology; D018562:Disease Transmission, Infectious / Q000517:prevention & control*; D006801:Humans; D008288:Malaria / Q000517:prevention & control* / Q000635:transmission; D017780:Malaria Vaccines; D010961:Plasmodium / Q000254:growth & development / Q000276:immunology*
D017780:Malaria Vaccines