title: Protective effect of energy metabolism regulators in alteration of gravitation load under experimental conditions.
abstract: Mitochondrial substrate-based preparations corrected disorders, caused by long-term exposure to abnormal gravitation vector in head-down tilt (hanging) test in rats. The preparations produced systemic and polyorgan protective effects consisting in correction of the blood prooxidant/antioxidant balance, energy metabolism in musculus soleus, and minimization of morphological changes in the liver and kidneys.
authors.affiliation: Institute of Biomedical Problems, Russian Academy of Sciences, Moscow.
authors.forename: N K
authors.initials: NK
authors.lastname: Mazina
authors.forename: I M
authors.initials: IM
authors.lastname: Larina
authors.forename: V A
authors.initials: VA
authors.lastname: Khazanov
authors.forename: B S
authors.initials: BS
authors.lastname: Shenkman
authors.forename: P I
authors.initials: PI
authors.lastname: Tsapok
authors.forename: V B
authors.initials: VB
authors.lastname: Zaitsev
authors.forename: V G
authors.initials: VG
authors.lastname: Khorobrykh
authors.forename: O M
authors.initials: OM
authors.lastname: Veselova
authors.forename: V S
authors.initials: VS
authors.lastname: Tret'yakov
mesh_terms: D000818:Animals; D000975:Antioxidants / Q000378:metabolism; D004734:Energy Metabolism / Q000187:drug effects; D006112:Gravitation; D018475:Head-Down Tilt; D008293:Malates / Q000494:pharmacology; D008297:Male; D008928:Mitochondria / Q000378:metabolism*; D016877:Oxidants / Q000097:blood; D051381:Rats; D017208:Rats, Wistar; D019802:Succinic Acid / Q000494:pharmacology
chemical_list: D000975:Antioxidants; D008293:Malates; D016877:Oxidants; C030298:malic acid; D019802:Succinic Acid