title: [Perforation risk in esophageal endoscopic mucosal resection with ligation: an experimental study with two ligator models].
abstract: OBJECTIVE
  endoscopic mucosal resection with ligation (EMRL) is considered an efficient, safe method for the treatment of some esophageal, gastric and colorectal tumors. We conducted this study using a porcine model in order to compare the safety of esophageal EMRL with two multiband ligation systems, since many centers only use these ligator models in EMRL (commercialized for varix ligation).
  
  
  METHODS
  eight pigs were used, which were submitted to 23 esophageal resections without previous injection. Ten resections were conducted using the Six Shooter Saeed model, and 13 resections used the Speedband Superview Super 7 model. The technique was also compared by making random cuts either above or below the band.
  
  
  RESULTS
  five perforations occurred, all of them using the Speedband model. This represents 38.5% of total in the Speedband model group. No perforation occurred when using the Six Shooter model (p = 0.046). On the contrary, no significant differences were found regarding frequency of perforation when cutting above or below the band.
  
  
  CONCLUSIONS
  esophageal EMRL using the Speedband model without previous injection leads to perforation in a high percentage of cases in an experimental animal model. Further studies are required to find out whether a previous injection may increase the safety of this technique with this ligator model.
authors.affiliation: Servicio de Aparato Digestivo, Complejo Hospitalario Universitario Juan Canalejo, La Coruña. manitos@telefonica.net
authors.forename: J L
authors.initials: JL
authors.lastname: Vázquez-Iglesias
authors.forename: P A
authors.initials: PA
authors.lastname: Alonso-Aguirre
authors.forename: A
authors.initials: A
authors.lastname: Centeno
authors.forename: E
authors.initials: E
authors.lastname: López
authors.forename: T
authors.initials: T
authors.lastname: Rodríguez
authors.forename: S
authors.initials: S
authors.lastname: Blanco
mesh_terms: D000818:Animals; D004724:Endoscopy; D004939:Esophageal Perforation / Q000209:etiology* / Q000517:prevention & control; D004947:Esophagus / Q000601:surgery*; D007431:Intraoperative Complications / Q000209:etiology* / Q000517:prevention & control; D008026:Ligation / Q000295:instrumentation; D009092:Mucous Membrane / Q000601:surgery; D012307:Risk Factors; D012449:Safety; D013552:Swine