title: Treating tobacco dependence: review of the best and latest treatment options.
abstract: Globally, an estimated 85% of lung cancer in men and 47% of lung cancer in women is attributable to tobacco smoking. Tobacco dependence treatment remains the most cost-effective way to prevent morbidity and mortality from lung cancer. Several effective pharmacotherapies are available to treat tobacco dependence. However, the long-term effectiveness of these treatments has been limited because the majority of smokers who attempt to stop smoking eventually relapse. Approaching the treatment of tobacco use and dependence as a chronic disease and the development of innovative drug therapies offer new hope for the treatment of tobacco-dependent patients. The diagnosis of lung cancer provides a teachable moment to motivate patients to attempt tobacco abstinence on which clinicians should capitalize. We review the currently available pharmacologic approaches to the treatment of tobacco dependence.
authors.affiliation: Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA. ebbert.jon@mayo.edu
authors.forename: Jon O
authors.initials: JO
authors.lastname: Ebbert
authors.forename: Amit
authors.initials: A
authors.lastname: Sood
authors.forename: J Taylor
authors.initials: JT
authors.lastname: Hays
authors.forename: Lowell C
authors.initials: LC
authors.lastname: Dale
authors.forename: Richard D
authors.initials: RD
authors.lastname: Hurt
mesh_terms: D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000209:etiology / Q000628:therapy; D008297:Male; D012907:Smoking / Q000009:adverse effects*; D016540:Smoking Cessation / Q000379:methods*; D014029:Tobacco Use Disorder / Q000188:drug therapy*