title: Voronoi analysis uncovers relationship between mosaics of normally placed and displaced amacrine cells in the thraira retina.
abstract: Although neuronal dynamics is to a high extent a function of synapse strength, the spatial distribution of neurons is also known to play an important role, which is evidenced by the topographical organization of the main stations of the visual system: retina, lateral geniculate nucleus, and cortex. The coexisting systems of normally placed and displaced amacrine cells in the vertebrate retina provide interesting examples of retinotopic spatial organization. However, it is not clear whether these two systems are spatially interrelated or not. The current work applies two mathematical-computational methods-a new method involving Voronoi diagrams for local density quantification and a more traditional approach, the Ripley K function-in order to characterize the mosaics of normally placed and displaced amacrine cells in the retina of Hoplias malabaricus and search for possible spatial relationships between these two types of mosaics. The results obtained by the Voronoi local density analysis suggest that the two systems of amacrine cells are spatially interrelated through nearly constant local density ratios.
authors.affiliation: Instituto de Física de São Carlos, Universidade de São Paulo, Caixa Postal 369, São Carlos, SP, 13560-970 Brazil. luciano@if.sc.usp.br
authors.forename: Luciano Da Fontoura
authors.initials: Lda F
authors.lastname: Costa
authors.forename: Daniela Maria Oliveira
authors.initials: DM
authors.lastname: Bonci
authors.forename: Cézar Akiyoshi
authors.initials: CA
authors.lastname: Saito
authors.forename: Fernando Allan De Farias
authors.initials: FA
authors.lastname: Rocha
authors.forename: Luiz Carlos De Lima
authors.initials: LC
authors.lastname: Silveira
authors.forename: Dora Fix
authors.initials: DF
authors.lastname: Ventura
mesh_terms: D025042:Amacrine Cells / Q000166:cytology*; D000818:Animals; D002450:Cell Communication / Q000502:physiology*; D005399:Fishes; D008432:Mathematical Computing; D012160:Retina / Q000166:cytology*; D012984:Software; D013569:Synapses / Q000502:physiology*; D014795:Visual Pathways / Q000033:anatomy & histology / Q000502:physiology