title: Cell microvesicles during experimental endotoxemia.
abstract: The dynamics of microvesicle formation in arterial blood in generalized Schwartzman phenomenon was studied. Successive (with 24-h interval) intravenous injections of endotoxin to rabbits in a dose of 1 mg/kg and 3 mg/kg caused an increase in the content of microvesicles in the blood, some of them containing ecto-5'-nucleotidase. Biphasic changes in arterial blood clotting time and erythrocyte hemolysis were observed.
authors.affiliation: Department of Biochemistry, Kazan State Medical University. dilja2001@mail.ru
authors.forename: L D
authors.initials: LD
authors.lastname: Zubairova
authors.forename: D M
authors.initials: DM
authors.lastname: Zubairov
authors.forename: I A
authors.initials: IA
authors.lastname: Andrushko
authors.forename: G Yu
authors.initials: GY
authors.lastname: Svintenok
authors.forename: I G
authors.initials: IG
authors.lastname: Mustafin
mesh_terms: D015720:5'-Nucleotidase / Q000097:blood; D000818:Animals; D019446:Endotoxemia / Q000473:pathology*; D004731:Endotoxins; D008070:Lipopolysaccharides; D008297:Male; D021962:Membrane Microdomains / Q000187:drug effects / Q000378:metabolism*; D011817:Rabbits; D012790:Shwartzman Phenomenon
chemical_list: D004731:Endotoxins; D008070:Lipopolysaccharides; D015720:5'-Nucleotidase