title: Enantioselective organocatalytic intramolecular ring-closing Friedel-Crafts-type alkylation of indoles.
abstract: An enantioselective organocatalytic intramolecular ring-closing Friedel-Crafts-type alkylation of indolyl alpha,beta-unsaturated aldehydes has been developed. This powerful new strategy allows enantioselective access to THPIs and THBCs in a straightforward and atom-economical manner.
authors.affiliation: Key Laboratory of Pesticide & Chemical Biology, Ministry of Education, College of Chemistry, Central China Normal University, Wuhan, Hubei, China.
authors.forename: Chang-Feng
authors.initials: CF
authors.lastname: Li
authors.forename: Hiu
authors.initials: H
authors.lastname: Liu
authors.forename: Jie
authors.initials: J
authors.lastname: Liao
authors.forename: Yi-Ju
authors.initials: YJ
authors.lastname: Cao
authors.forename: Xiao-Peng
authors.initials: XP
authors.lastname: Liu
authors.forename: Wen-Jing
authors.initials: WJ
authors.lastname: Xiao
mesh_terms: D000447:Aldehydes / Q000737:chemistry; D000478:Alkylation; D002384:Catalysis; D018360:Crystallography, X-Ray; D003500:Cyclization; D007211:Indoles / Q000138:chemical synthesis / Q000737:chemistry*; D008958:Models, Molecular; D015394:Molecular Structure; D013237:Stereoisomerism
chemical_list: D000447:Aldehydes; D007211:Indoles