Recent immunologic considerations regarding the itch and treatment of scabies.
Scabies continues to be a major public health problem. Recent findings reveal that these mites produce substances that modulate the host's immune response resulting in the latency period prior to symptoms. In terms of treatment, two cases of ivermectin resistance have come to fore in Australia in patients treated over fifty times with the agent. Additionally, work in the development of vaccination of hosts with antigenic midgut proteins of mites to control ectoparasitic infestations continues.
Burkhart
Craig G
CG
Medical University of Ohio at Toledo, USA. cgbakb@aol.com
D000818:Animals; D000977:Antiparasitic Agents / Q000627:therapeutic use; D004351:Drug Resistance; D006801:Humans; D007559:Ivermectin / Q000627:therapeutic use; D011537:Pruritus / Q000276:immunology*; D012520:Sarcoptes scabiei / Q000276:immunology*; D012532:Scabies / Q000150:complications / Q000188:drug therapy / Q000276:immunology* / Q000517:prevention & control; D014612:Vaccines
D000977:Antiparasitic Agents; D014612:Vaccines; D007559:Ivermectin