title: Video-capsule endoscopy gastric and small bowel transit time and completeness of the examination in patients with diabetes mellitus.
abstract: BACKGROUND
  Small intestine video-capsule endoscopy examination in patients with diabetes mellitus may be incomplete due to delayed gastric emptying.
  
  
  OBJECTIVE
  To measure video-capsule endoscopy gastric and small bowel transit time and to assess the completeness of the examination in diabetes mellitus patients.
  
  
  METHODS
  In this retrospective, case-control study, we examined capsule endoscopy videos from 29 consecutive diabetes mellitus patients. Fifty-eight matched for sex, type of preparation, age and reason for referral non-diabetic controls were selected from our video-capsule endoscopy database. Two independent experienced investigators measured transit times and assessed examinations' completeness.
  
  
  RESULTS
  Video-capsule endoscopy gastric transit time was significantly longer in diabetes mellitus (87, 1-478 min) compared to non-diabetic patients (24, 4-108 min, p<0.001). The caecum was visualized in 20/29 (69%) diabetes mellitus and 52/58 (89.6%) non-diabetic controls (p=0.02). In 16 diabetes mellitus patients that video-capsule endoscopy reached the caecum, small bowel transit time was significantly shorter (261.2+/-55.5 min) compared to their 32 non-diabetic matched controls (302+/-62.7 min, p=0.03).
  
  
  CONCLUSIONS
  Patients with type 2 diabetes mellitus have prolonged video-capsule endoscopy gastric transit time compared to non-diabetic patients. Prospective studies are required to complete our understanding of video-capsule endoscopy transit times in the setting of diabetes mellitus.
authors: Hepato-Gastroenterology Unit, 2nd Department of Internal Medicine, Medical School, Athens University, Attikon University General Hospital, 124 62 Haidari, Athens, Greece. ktriant@med.uoa.gr
authors: K
authors: K
authors: Triantafyllou
authors: C
authors: C
authors: Kalantzis
authors: A A
authors: AA
authors: Papadopoulos
authors: P
authors: P
authors: Apostolopoulos
authors: T
authors: T
authors: Rokkas
authors: N
authors: N
authors: Kalantzis
authors: S D
authors: SD
authors: Ladas
mesh_terms: D053704:Capsule Endoscopy; D016022:Case-Control Studies; D003920:Diabetes Mellitus / Q000503:physiopathology*; D005260:Female; D005772:Gastrointestinal Transit / Q000502:physiology*; D006801:Humans; D007421:Intestine, Small / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D015588:Observer Variation; D010808:Physical Examination