title: Protein S100B after cardiac surgery: an indicator of long-term anxiety?
abstract: OBJECTIVE
  The aim of the study was to assess long-term state and trait anxiety in cardiac surgical risk patients.
  
  
  METHODS
  Thirty two patients with serum S100B>0.3 microg/l 48 hours after cardiac surgery with cardiopulmonary bypass were matched according to age, gender, type, date and length of surgery with 35 operated patients without elevated S100B. They completed Spielberger's Anxiety Inventory (STAI).
  
  
  RESULTS
  Patients with elevated S100B reported more state anxiety and trait anxiety. S100B was an independent predictor of both state and trait anxiety when controlling for perioperative variables.
  
  
  CONCLUSIONS
  Patients with elevated S100B reported more anxiety 3-6 years after cardiac surgery. A postoperative blood sample can identify risk patients and facilitate appropriate follow-up.
authors: Department of Psychology, Lund University, Lund, Sweden. cecilia.dautovic_bergh@psychology.lu.se
authors: Cecilia Dautovic
authors: CD
authors: Bergh
authors: Martin
authors: M
authors: Bäckström
authors: Katarina
authors: K
authors: Axelsson
authors: Henrik
authors: H
authors: Jönsson
authors: Per
authors: P
authors: Johnsson
mesh_terms: D000368:Aged; D001007:Anxiety / Q000209:etiology* / Q000503:physiopathology; D015415:Biomarkers / Q000097:blood; D006348:Cardiac Surgical Procedures / Q000009:adverse effects / Q000523:psychology*; D004644:Emotions; D005260:Female; D006801:Humans; D008297:Male; D009414:Nerve Growth Factors / Q000097:blood*; D010555:Personality Inventory; D011183:Postoperative Complications / Q000523:psychology*; D012189:Retrospective Studies; D018570:Risk Assessment; D012307:Risk Factors; D064568:S100 Calcium Binding Protein beta Subunit; D009418:S100 Proteins / Q000097:blood*; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D015415:Biomarkers; D009414:Nerve Growth Factors; D064568:S100 Calcium Binding Protein beta Subunit; D009418:S100 Proteins; C579160:S100B protein, human