title: Interventional trials involving patients cannot be performed safely without a control group treated with the standard of care.
authors: Herwig-Ulf
authors: HU
authors: Meier-Kriesche
authors: Jesse D
authors: JD
authors: Schold
authors: Henrik
authors: H
authors: Ekberg
mesh_terms: D002986:Clinical Trials as Topic / Q000379:methods* / Q000592:standards*; D035061:Control Groups; D018849:Controlled Clinical Trials as Topic / Q000379:methods / Q000592:standards; D006801:Humans; D005791:Patient Care / Q000592:standards*