title: Stimulated whole salivary flow rate and composition in menopausal women with oral dryness feeling.
abstract: The aim of this study was to compare stimulated whole saliva flow rate and composition of menopausal women with/without oral dryness (OD) feeling. A case-control study was carried out in 42 selected menopausal women aged 52-73 years with or without OD feeling (21 as case and 21 as control) conducted at the Clinic of Oral Medicine, Tehran University of Medical Sciences. Paraffin-stimulated saliva samples were obtained by expectoration. The stimulated whole saliva composition was measured by a spectrophotometer [magnesium (Mg(+2)), calcium (Ca(+2)), chloride (Cl(-)), inorganic phosphate (Pi) and total protein], flame-photometry [sodium (Na(+))] and ion selective electrode (ISE) [potassium (K(+))] methods. No significant differences were found in stimulated whole saliva flow rate, Mg(+2), Cl(-), Pi, Na(+), K(+) and total protein concentrations between the two groups, but the mean calcium concentration was significantly higher in cases than in controls (P = 0.003). It seems that the level of salivary calcium concentration may be higher in menopausal women with OD feeling than in the control group.
authors: Department of Oral Medicine, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran. aghahose@sina.tums.ac.ir
authors: F
authors: F
authors: Agha-Hosseini
authors: I
authors: I
authors: Mirzaii-Dizgah
authors: P P
authors: PP
authors: Moghaddam
authors: Z T
authors: ZT
authors: Akrad
mesh_terms: D000368:Aged; D002118:Calcium / Q000032:analysis; D016022:Case-Control Studies; D002712:Chlorides / Q000032:analysis; D005260:Female; D006801:Humans; D008274:Magnesium / Q000032:analysis; D008875:Middle Aged; D010710:Phosphates / Q000032:analysis; D017698:Postmenopause / Q000502:physiology*; D011188:Potassium / Q000032:analysis; D012463:Saliva / Q000737:chemistry* / Q000378:metabolism*; D012471:Salivary Proteins and Peptides / Q000032:analysis; D012636:Secretory Rate; D012964:Sodium / Q000032:analysis; D011795:Surveys and Questionnaires; D014987:Xerostomia / Q000503:physiopathology*
chemical_list: D002712:Chlorides; D010710:Phosphates; D012471:Salivary Proteins and Peptides; D012964:Sodium; D008274:Magnesium; D011188:Potassium; D002118:Calcium