title: Mid-term survival after abdominal aortic aneurysm surgery predicted by cardiopulmonary exercise testing.
abstract: BACKGROUND
  Cardiopulmonary exercise (CPX) testing measures how efficiently subjects meet increased metabolic demand. This study aimed to determine whether preoperative CPX testing predicted postoperative survival following elective abdominal aortic aneurysm (AAA) repair.
  
  
  METHODS
  Some 130 patients had CPX testing before elective open AAA repair. Additional preoperative, operative and postoperative variables were recorded prospectively. Median follow-up was 35 months. The correlation of variables with survival was assessed by single and multiple regression analyses.
  
  
  RESULTS
  CPX testing identified 30 of 130 patients who had been unfit before surgery. Two years after surgery the Kaplan-Meier survival estimate was 55 per cent for the 30 unfit patients, compared with 97 per cent for the 100 fit patients. The absolute difference in survival between these two groups at 2 years was 42 (95 per cent confidence interval 18 to 65) per cent (P < 0.001).
  
  
  CONCLUSIONS
  Preoperative CPX testing, combined with simple co-morbidity scoring, identified patients unlikely to survive in the mid-term, even after successful AAA repair.
authors: Department of Anaesthesia and Critical Care Medicine, Torbay Hospital, Torquay TQ2 7AA, UK. john.carlisle@nhs.net
authors: J
authors: J
authors: Carlisle
authors: M
authors: M
authors: Swart
mesh_terms: D000704:Analysis of Variance; D017544:Aortic Aneurysm, Abdominal / Q000401:mortality / Q000503:physiopathology / Q000601:surgery*; D002245:Carbon Dioxide / Q000378:metabolism; D017558:Elective Surgical Procedures; D005080:Exercise Test; D006801:Humans; D008449:Maximal Expiratory Flow-Volume Curves / Q000502:physiology; D010101:Oxygen Consumption; D010809:Physical Fitness; D011183:Postoperative Complications / Q000401:mortality* / Q000503:physiopathology; D011300:Preoperative Care / Q000379:methods; D018570:Risk Assessment; D016019:Survival Analysis
chemical_list: D002245:Carbon Dioxide