[On the way to understand the mechanism of immune tolerance].
This introductory paper deals with mechanisms playing important role in the development of immunological tolerance. Discusses the problems of "immunological self" and "non-self", the importance of the roles of AIRE gene products, as well as the role of dendritic cells and regulatory T-cells (T-reg cells) in immune tolerance and autoimmunity.
Gergely
János
J
Eötvös Loránd Tudományegyetem, Immunológiai Tanszék, Budapest. janos.gergely@freemail.hu
D000818:Animals; D003713:Dendritic Cells / Q000276:immunology*; D006801:Humans; D007108:Immune Tolerance / Q000235:genetics / Q000276:immunology / Q000502:physiology; D050378:T-Lymphocytes, Regulatory / Q000276:immunology*; D014157:Transcription Factors / Q000235:genetics*; D000096927:AIRE Protein
D014157:Transcription Factors; D000096927:AIRE Protein