Hold on, the monocytes are coming!
The role that monocyte-derived dendritic cells play in vivo remains enigmatic. León et al. (2007) now show that these cells develop "on demand" at a site of Leishmania infection to promote a life-saving T helper 1 immune response.
Villadangos
Jose A
JA
Immunology Division, The Walter and Eliza Hall Institute, 1G Royal Parade Parkville, Victoria 3050, Australia. villadangos@wehi.edu.au
D000818:Animals; D016773:Leishmaniasis, Cutaneous / Q000276:immunology*; D051379:Mice; D009000:Monocytes / Q000276:immunology*; D018417:Th1 Cells / Q000276:immunology*