Future of infertility treatment.
The development of techniques to prolong the window of fertility for women has the ability to meet the needs of future populations and their delay in childbearing. With current techniques of cryopreservation of embryos, oocytes, or ovarian tissue, prolongation of fertility with varying success is feasible. In the future, rejuvenation of aging oocytes will offer the opportunity for the aging women to achieve pregnancy with their own genetic offspring. Production of germ cells from embryonic stem cells is another alternative for patient with poor or depleted germ cells. Better understanding of the cause of infertility can be achieved with new techniques to evaluate the oocytes, spermatozoa, and embryos on molecular and genetic levels. With improved understanding of the etiology of infertility, treatment will be more effective. With the advance of new drugs and surgical equipment, treatment of infertility will become more convenient and effective.
Manipalviratn
Somjate
S
Department of Obstetrics and Gynecology, David Geffen School of Medicine, University of California, Los Angeles, California 90095, USA.
Huang
Andy
A
Decherney
Alan H
AH
D000818:Animals; D002454:Cell Differentiation; D015925:Cryopreservation; D053938:DNA Fragmentation; D053595:Embryonic Stem Cells / Q000502:physiology; D005260:Female; D006801:Humans; D020287:In Situ Nick-End Labeling; D007247:Infertility, Female / Q000628:therapy*; D008297:Male; D012099:Reproductive Techniques / Q000639:trends*; D012371:Robotics; D013094:Spermatozoa / Q000502:physiology; D019098:Telomerase / Q000378:metabolism
D019098:Telomerase