title: Systemic sclerosis sine scleroderma associated with Wolff-Parkinson-White syndrome.
abstract: The term "systemic sclerosis sine scleroderma" (ssSSc) has been used to designate a rare progressive systemic sclerosis of visceral organs without skin manifestations. A variety of visceral organs, including the gastrointestinal tract, lung, heart, and kidney, can be involved. We describe a case of 59-year-old female patient with both Wolff-Parkinson-White (WPW) syndrome and ssSSc. She was diagnosed as having ssSSc with Raynaud's phenomenon, anti-nuclear antibody (ANA) and anti-topoisomerase antibody positivity, interstitial pulmonary infiltrates, suspected pulmonary hypertension, subclinical oesophageal dysmotility but no skin thickening. She had a history of paroxysmal tachycardia together with Raynaud's phenomenon and exercise-induced dyspnoea. Electrophysiological study confirmed WPW syndrome with left posterior bypass tract. This case highlights cardiac arrhythmia caused by WPW syndrome as a clinical manifestation of the heart in ssSSc.
authors: Department of Rheumatology, Chonnam National University Medical School, University Hospital, 8 Hak-Dong, Dong-Ku, Gwangju 501-757, Republic of Korea. ppaarrkkyw@empal.com
authors: Y-W
authors: YW
authors: Park
authors: H
authors: H
authors: Woo
authors: H-J
authors: HJ
authors: Yoon
authors: H-W
authors: HW
authors: Park
authors: J-G
authors: JG
authors: Cho
authors: S-S
authors: SS
authors: Shin
authors: S-S
authors: SS
authors: Lee
mesh_terms: D005260:Female; D006801:Humans; D008875:Middle Aged; D012595:Scleroderma, Systemic / Q000150:complications* / Q000175:diagnosis; D014927:Wolff-Parkinson-White Syndrome / Q000150:complications* / Q000175:diagnosis