[Updates in practical neurology--I. The principles of modern levodopa therapy in Parkinson's disease].
Despite the levodopa is used for the treatment of Parkinson's disease for a long time, recently many questions raised about its clinical use. New issues emerged based on the clinical trials, on latest neuroimaging data and on better understanding the pathomechanism of motor complications. These observations have changed the routine clinical use of levodopa. In this review we summarize the evidences and practical implications of levodopa therapy.
Klivényi
Péter
P
Neurológiai Klinika, Szeged. klivenyi@nepsy.szote.u-szeged.hu
Vécsei
László
L
D000978:Antiparkinson Agents / Q000009:adverse effects / Q000627:therapeutic use*; D004298:Dopamine / Q000378:metabolism*; D015259:Dopamine Agents / Q000009:adverse effects / Q000627:therapeutic use*; D019317:Evidence-Based Medicine; D006801:Humans; D007980:Levodopa / Q000009:adverse effects / Q000627:therapeutic use*; D010300:Parkinson Disease / Q000188:drug therapy* / Q000378:metabolism
D000978:Antiparkinson Agents; D015259:Dopamine Agents; D007980:Levodopa; D004298:Dopamine