title: Simultaneously acute hepatitis B virus and C virus coinfection and subsequent chronic hepatitis C.
abstract: Hepatitis C virus (HCV) and hepatitis B virus (HBV) share similar transmission routes, but concurrent acute HCV and HBV infection was rarely reported. Little is known about viral interaction and hepatic biochemical features of acute HBV and HCV coinfection. We report an intravenous drug abuser with simultaneous acute HBV and HCV infections presenting as biphasic elevation of both alanine aminotransferase (ALT) and total bilirubin levels. HCV infection is the major cause of continuing hepatitis after termination of HBsAg antigenemia.
authors: Liver Research Unit, Department of Pathology, Chang-Gung Memorial Hospital and Institute of Technology, Keelung, Taiwan.
authors: Shuo-Wei
authors: SW
authors: Chen
authors: Tsung-Shih
authors: TS
authors: Lee
authors: Ching-Chih
authors: CC
authors: Hu
authors: Liang-Che
authors: LC
authors: Chang
authors: Rong-Nan
authors: RN
authors: Chien
mesh_terms: D000328:Adult; D000410:Alanine Transaminase / Q000097:blood; D001663:Bilirubin / Q000097:blood; D006509:Hepatitis B / Q000097:blood / Q000150:complications* / Q000276:immunology; D006510:Hepatitis B Antibodies / Q000097:blood; D006513:Hepatitis B e Antigens / Q000097:blood; D006526:Hepatitis C / Q000097:blood / Q000150:complications* / Q000276:immunology; D018937:Hepatitis C Antibodies / Q000097:blood; D019698:Hepatitis C, Chronic / Q000209:etiology* / Q000276:immunology; D006801:Humans; D008297:Male; D015819:Substance Abuse, Intravenous / Q000821:virology*
chemical_list: D006510:Hepatitis B Antibodies; D006513:Hepatitis B e Antigens; D018937:Hepatitis C Antibodies; D000410:Alanine Transaminase; D001663:Bilirubin