title: Early versus late intravitreal triamcinolone acetonide for macular edema associated with branch retinal vein occlusion.
abstract: OBJECTIVE
  To compare the effect of early versus late intravitreal injection of triamcinolone in patients with macular edema due to branch retinal vein occlusion (BRVO).
  
  
  METHODS
  Twenty eyes of 20 patients with macular edema from BRVO, including 10 with duration after onset of or <or= 3 months and 10 with duration of 3 months, were treated using a single intravitreal triamcinolone injection (4 mg/0.1 ml). Best-corrected visual acuity and foveal thickness by optical coherence tomography were measured 1, 3, and 6 months post-injection.
  
  
  RESULTS
  In patients that received treatment after a disease duration of <or= 3 months, visual acuity and foveal thickness significantly improved from baseline over 6 months of follow-up. However, in those with a duration of >3 months, improvements in visual acuity and foveal thickness, though apparent at 1 month, were not maintained at 3 and 6 months post-triamcinolone.
  
  
  CONCLUSIONS
  Intravitreal triamcinolone is more effective in patients with BRVO who are treated earlier.
authors: Department of Ophthalmology, Seoul National University College of Medicine, Chongno-gu, Seoul, Korea.
authors: Joo Youn
authors: JY
authors: Oh
authors: Je Hyun
authors: JH
authors: Seo
authors: Jae Kyoun
authors: JK
authors: Ahn
authors: Jang Won
authors: JW
authors: Heo
authors: Hum
authors: H
authors: Chung
mesh_terms: D004334:Drug Administration Schedule; D005260:Female; D005584:Fovea Centralis / Q000187:drug effects; D005938:Glucocorticoids / Q000008:administration & dosage* / Q000627:therapeutic use; D006801:Humans; D008269:Macular Edema / Q000139:chemically induced / Q000188:drug therapy* / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D012170:Retinal Vein Occlusion / Q000150:complications*; D041623:Tomography, Optical Coherence; D016896:Treatment Outcome; D014222:Triamcinolone Acetonide / Q000008:administration & dosage* / Q000627:therapeutic use; D014792:Visual Acuity / Q000187:drug effects
chemical_list: D005938:Glucocorticoids; D014222:Triamcinolone Acetonide