Heart fatty acid binding protein is upregulated during porcine adipocyte development.
Heart fatty acid binding protein (H-FABP) has been associated with intramuscular fat content in pigs. In the current study, we showed that expression of H-FABP mRNA in adipose tissue of adult pigs was 8.5% of that in heart and 30% of that in skeletal muscle, and that H-FABP mRNA level was more than 10% of that of adipocyte fatty acid binding protein mRNA in adipose tissue. Levels of H-FABP mRNA reached a maximum in adipose tissue from 7-d neonates, with no further increase in the adult. Also, H-FABP mRNA was induced during adipogenic differentiation of stromal-vascular cells derived from adipose tissue and skeletal muscle. In conclusion, H-FABP may play a role in adipose tissue development and function in the pig.
Li
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B
Department of Animal Sciences, Ohio State University, Columbus, OH 43210, USA.
Zerby
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HN
Lee
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K
D000273:Adipose Tissue / Q000378:metabolism*; D000367:Age Factors; D000375:Aging / Q000378:metabolism / Q000502:physiology; D000818:Animals; D001823:Body Composition; D050556:Fatty Acid-Binding Proteins / Q000378:metabolism*; D018482:Muscle, Skeletal / Q000378:metabolism*; D009206:Myocardium / Q000378:metabolism*; D012333:RNA, Messenger / Q000378:metabolism*; D013552:Swine / Q000254:growth & development / Q000378:metabolism*; D015854:Up-Regulation
D050556:Fatty Acid-Binding Proteins; D012333:RNA, Messenger