title: Sero-prevalence of brucellosis in occupationally exposed people in Addis Ababa, Ethiopia.
abstract: OBJECTIVE
  Brucellosis is a Zoonosis, recognized worldwide as a serious public health hazard and economically significant disease. The etiologic agent of this disease is a bacterial species of the genus Brucella that causes undulant fever, sterility and other systemic illnesses in human. Thus, the aim of this study was to undertake seroepidemiological study of brucellosis on occupationally exposed persons in Addis Ababa abattoirs enterprise and different dairy farms.
  
  
  METHODS
  Three hundred thirty six human individuals were screened using Rose Bengal Plate Test (RBPT) and the sera were further subjected to 2- Mercapto Ethanol Test (2-MET). Simultaneously, survey was conducted in farms and slaughterhouse to investigate epidemiological factors.
  
  
  RESULTS
  An overall seroprevalence rate of 4.8% (16/336) was determined by taking RBPT+/2MET+ as confirmatory test (P < 0.05). Some of the risk factors contributing to the occurrence of the disease include occupation, gender, and unsafe handling of infected materials. Raw milk and meat consumption, lack of awareness and use of detergents were also found as important factors.
  
  
  CONCLUSIONS
  The seroprevalence of brucellosis is expected to be more in other areas of the Region, where there is high human-animal contact and high number of cattle population with a respective traditional system of animal rearing.
authors: Infectious and Other Diseases Research Department, Ethiopian Health and Nutrition Research Institute, P.O. Box 1242, Addis Ababa, Ethiopia.
authors: Jiksa
authors: J
authors: Kassahun
authors: Eshetu
authors: E
authors: Yimer
authors: Abera
authors: A
authors: Geyid
authors: Paulos
authors: P
authors: Abebe
authors: Bethlehem
authors: B
authors: Newayeselassie
authors: Badeg
authors: B
authors: Zewdie
authors: Mekoro
authors: M
authors: Beyene
authors: Abebe
authors: A
authors: Bekele
mesh_terms: D000003:Abattoirs; D000328:Adult; D000383:Agriculture; D000818:Animals; D002006:Brucellosis / Q000097:blood / Q000175:diagnosis / Q000453:epidemiology*; D003430:Cross-Sectional Studies; D003612:Dairying; D005002:Ethiopia / Q000453:epidemiology; D005260:Female; D006801:Humans; D008297:Male; D016273:Occupational Exposure / Q000009:adverse effects* / Q000032:analysis / Q000706:statistics & numerical data; D012307:Risk Factors; D016036:Seroepidemiologic Studies; D015047:Zoonoses