Luminescent lanthanide bimetallic triple-stranded helicates as potential cellular imaging probes.
Water-soluble triple-stranded [Ln(2)(L)(3)] helicates have been successfully tested as imaging probes in human cervical adenocarcinoma cells (HeLa), the complex being not toxic and clearly staining their cytoplasm in a concentration-dependent manner.
Vandevyver
Caroline D B
CD
Laboratory of Lanthanide Supramolecular Chemistry, Ecole Polytechnique Fédérale de Lausanne (EPFL), BCH 1405, 1015 Lausanne, Switzerland. caroline.vandevyver@epfl.ch
Chauvin
Anne-Sophie
AS
Comby
Steve
S
Bünzli
Jean-Claude G
JC
D049109:Cell Proliferation / Q000187:drug effects; D006367:HeLa Cells; D006801:Humans; D028581:Lanthanoid Series Elements / Q000737:chemistry* / Q000494:pharmacology; D008024:Ligands; D008163:Luminescent Measurements; D015394:Molecular Structure
D028581:Lanthanoid Series Elements; D008024:Ligands