title: Evaluation of 13C-urea breath test and fecal antigen immunoassay to detect Helicobacter pylori infection in Gambian infants.
abstract: Helicobacter pylori colonization was measured by [13C]-urea breath test in 198 Gambian infants and by fecal enzyme-linked immunosorbent assay in 52 of the 198 at ages 2, 5, and 12 months. By 12 months there was good concordance between tests; 33 of 44 (75%) test results were positive by enzyme-linked immunosorbent assay, and 29 of 44 (66%) test results were positive by urea breath test. H. pylori colonization is common among Gambian infants, and noninvasive tests can provide a reliable means of diagnosis.
authors: University of Newcastle, School of Clinical Medical Sciences, Newcastle-upon-Tyne, UK.
authors: Rhys T
authors: RT
authors: Jones
authors: Momodou K
authors: MK
authors: Darboe
authors: Conor P
authors: CP
authors: Doherty
authors: William G
authors: WG
authors: MacKay
authors: Lawrence T
authors: LT
authors: Weaver
authors: David I
authors: DI
authors: Campbell
authors: Julian E
authors: JE
authors: Thomas
mesh_terms: D000942:Antigens, Bacterial / Q000302:isolation & purification; D001944:Breath Tests / Q000379:methods*; D004797:Enzyme-Linked Immunosorbent Assay; D005243:Feces / Q000382:microbiology*; D005714:Gambia; D016481:Helicobacter Infections / Q000175:diagnosis*; D016480:Helicobacter pylori / Q000302:isolation & purification*; D006801:Humans; D007223:Infant; D011446:Prospective Studies
chemical_list: D000942:Antigens, Bacterial