title: Enhanced iturin A production by Bacillus subtilis and its effect on suppression of the plant pathogen Rhizoctonia solani.
abstract: Enhanced production of the antibiotic iturin A by Bacillus subtilis RB14-CS reached 4.4 g L(-1) in SM medium containing soybean meal and maltose, which was 16-fold and 2.2-fold higher than that in original and modified number 3S media, respectively. When various volumes of RB14-CS cultures grown in SM medium were applied to pot tests of tomato damping-off caused by Rhizoctonia solani, damping-off was dose-dependently suppressed by the cultures. Suppression by SM-grown cultures was significantly more effective than that by cultures grown in original or modified number 3S media. The iturin A concentrations in soil decreased to undetectable levels after 17 days of cultivation in pot tests, indicating that iturin A has a low persistence in soil.
authors: Chemical Resources Laboratory, Tokyo Institute of Technology, R1-29-4259 Nagatsuta, Midori-ku, Yokohama 226-8503, Japan.
authors: S
authors: S
authors: Mizumoto
authors: M
authors: M
authors: Hirai
authors: M
authors: M
authors: Shoda
mesh_terms: D000935:Antifungal Agents / Q000096:biosynthesis* / Q000494:pharmacology; D001412:Bacillus subtilis / Q000378:metabolism*; D018929:Cell Culture Techniques; D010456:Peptides, Cyclic / Q000096:biosynthesis* / Q000494:pharmacology; D012232:Rhizoctonia / Q000187:drug effects*
chemical_list: D000935:Antifungal Agents; D010456:Peptides, Cyclic; C013579:iturin A