Solid cystic papillary tumor of pancreas in eight children.
OBJECTIVE
To estimate the clinical and pathological features of pancreatic solid cystic papillary tumor (SCPT) in children.


METHODS
From 2000 to 2005, 8 cases with SCPT of the pancreas were analyzed retrospectively. All cases but one were females. Average age was 12.8 years. By case review, we discussed the clinical and pathological features of SCPT in children.


RESULTS
The chief complains were abdominal pain and palpable mass. There were 3 cases in the head, 1 case in the body, and 4 cases in the tail of pancreas. The procedures employed included local resection (1 case), distal pancreatectomy (5 cases), pancreaticoduodenectomy (1 case), and biopsy (1 case). Histological examination showed solid with cystic areas and papillary protrusions in the 8 cases; as for immunohistochemical examinations, the positive rate was 100% for alpha-antitrypsin (AACT), 87.5% for vinmentin, and 62.5% for neuron-specific enolase (NSE). The patients were followed up for 2 months to 4 years but one was lost by follow-up and all were alive postoperatively. SCPT in 2 cases relapsed.


CONCLUSIONS
Occurring predominantly in young females, SCPT is usually curable by surgical resection with a favorable prognosis.
Zhang
Ke-Ren
KR
Department of Pediatric Surgery, Second Affiliated Hospital, China Medical University, Shenyang 110004. zkr425@yahoo.com
Jia
Hui-Min
HM
Shu
Hong
H
Li
Xin-Yuan
XY
D000293:Adolescent; D002648:Child; D018292:Cystadenoma, Papillary / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D004386:Duodenum / Q000601:surgery; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D010180:Pancreatectomy; D010190:Pancreatic Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D011379:Prognosis; D012189:Retrospective Studies; D013156:Splenectomy; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome