title: Optimizing the laser-pulse configuration for coherent Raman spectroscopy.
abstract: We introduce a hybrid technique that combines the robustness of frequency-resolved coherent anti-Stokes Raman scattering (CARS) with the advantages of time-resolved CARS spectroscopy. Instantaneous coherent broadband excitation of several characteristic molecular vibrations and the subsequent probing of these vibrations by an optimally shaped time-delayed narrowband laser pulse help to suppress the nonresonant background and to retrieve the species-specific signal. We used this technique for coherent Raman spectroscopy of sodium dipicolinate powder, which is similar to calcium dipicolinate (a marker molecule for bacterial endospores, such as Bacillus subtilis and Bacillus anthracis), and we demonstrated a rapid and highly specific detection scheme that works even in the presence of multiple scattering.
authors: Institute for Quantum Studies and Departments of Physics and Chemical Engineering, Texas A&M University, College Station, TX 77843, USA. dmip@neo.tamu.edu
authors: Dmitry
authors: D
authors: Pestov
authors: Robert K
authors: RK
authors: Murawski
authors: Gombojav O
authors: GO
authors: Ariunbold
authors: Xi
authors: X
authors: Wang
authors: Miaochan
authors: M
authors: Zhi
authors: Alexei V
authors: AV
authors: Sokolov
authors: Vladimir A
authors: VA
authors: Sautenkov
authors: Yuri V
authors: YV
authors: Rostovtsev
authors: Arthur
authors: A
authors: Dogariu
authors: Yu
authors: Y
authors: Huang
authors: Marlan O
authors: MO
authors: Scully
mesh_terms: D001412:Bacillus subtilis / Q000302:isolation & purification; D007834:Lasers; D010848:Picolinic Acids / Q000032:analysis; D013059:Spectrum Analysis, Raman / Q000379:methods*; D013171:Spores, Bacterial / Q000302:isolation & purification
chemical_list: D010848:Picolinic Acids; C004860:dipicolinic acid