title: A novel endovascular adjustable polytetrafluoroethylene-covered stent for the management of hepatic encephalopathy after transjugular intrahepatic portosystemic shunt.
abstract: Transjugular intrahepatic portosystemic shunt (TIPS) is frequently complicated by hepatic encephalopathy. When medical therapy fails, TIPS narrowing and resultant increase in the portosystemic pressure gradient and blood flow to the liver is performed in order to reverse the encephalopathy. We present a method for reducing the TIPS using a polytetrafluoroethylene-covered balloon expandable stent placed over a self-expanding stent. This results in a narrowed TIPS that not only rapidly increases the portosystemic gradient but also can be adjusted by dilating the balloon expandable stent. This method was successful in narrowing the patient's TIPS, acutely increasing the portosystemic gradient and reversing the hepatic encephalopathy.
authors: Mount Sinai School of Medicine, One Gustave L. Levy Place, New York, NY 10029, USA. Joshua.Weintraub@mountsinai.org
authors: Joshua L
authors: JL
authors: Weintraub
authors: David G
authors: DG
authors: Mobley
authors: Michael E
authors: ME
authors: Weiss
authors: Eli
authors: E
authors: Swanson
authors: Nishita
authors: N
authors: Kothary
mesh_terms: D000368:Aged; D000800:Angioplasty, Balloon; D017809:Fatal Outcome; D005260:Female; D006501:Hepatic Encephalopathy / Q000000981:diagnostic imaging / Q000209:etiology / Q000503:physiopathology / Q000628:therapy*; D006801:Humans; D006975:Hypertension, Portal / Q000503:physiopathology / Q000601:surgery*; D008102:Liver Circulation; D011138:Polytetrafluoroethylene; D017082:Portal Pressure; D019168:Portasystemic Shunt, Transjugular Intrahepatic / Q000009:adverse effects*; D011172:Portography; D011474:Prosthesis Design; D012189:Retrospective Studies; D015607:Stents
chemical_list: D011138:Polytetrafluoroethylene