title: Zfx: at the crossroads of survival and self-renewal.
abstract: As the molecular mechanisms that govern stem cell fate are beginning to be unraveled, Galan-Caridad et al. (2007) report in this issue of Cell a common role for the transcription factor Zfx in the self-renewal/maintenance of both embryonic stem cells and hematopoietic stem cells. Their work suggests that a regulator of self-renewal can be shared between two different cell types.
authors: Laboratory of Molecular Genetics of Stem Cells, Institute for Research in Immunology and Cancer (IRIC), C.P. 6128 succursale Centre-Ville, Montréal, Québec H3C 3J7, Canada.
authors: Sonia
authors: S
authors: Cellot
authors: Guy
authors: G
authors: Sauvageau
mesh_terms: D000818:Animals; D002454:Cell Differentiation; D002470:Cell Survival; D053595:Embryonic Stem Cells / Q000166:cytology* / Q000378:metabolism; D006412:Hematopoietic Stem Cells / Q000166:cytology* / Q000378:metabolism; D051741:Kruppel-Like Transcription Factors / Q000378:metabolism*; D051379:Mice
chemical_list: D051741:Kruppel-Like Transcription Factors; C062076:zinc finger protein, X-linked