Azathioprine-induced squamous cell carcinoma of the kidney.
Immunosuppressive therapy with azathioprine has been documented to cause squamous cell carcinoma (SCC) at various sites. We report possibly the first case of SCC of the kidney in a young male who received azathioprine for a long time. Discontinuation of azathioprine post-radical nephrectomy probably increased the patient's metastatic disease-free survival.
Nair
Balagopal
B
Department of Urology, Amrita Institute of Medical Sciences and Research Centre, Kochi, Kerala, India. urology@aims.amrita.edu
Sukumar
Sudhir
S
Poolari
Ginil Kumar
GK
Appu
Thomas
T
D000328:Adult; D001379:Azathioprine / Q000009:adverse effects*; D002294:Carcinoma, Squamous Cell / Q000139:chemically induced*; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects*; D007680:Kidney Neoplasms / Q000139:chemically induced*; D008297:Male
D007166:Immunosuppressive Agents; D001379:Azathioprine