title: Structures of pahayokolides A and B, cyclic peptides from a Lyngbya sp.
abstract: The isolation and structure elucidation of two cyclic peptides, pahayokolides A (1) and B (2), is described. Structural features determined for these compounds include a pendent N-acetyl-N-methyl leucine, both E- and Z-dehydrobutyrines, a homophenylalanine, and an unusual polyhydroxy amino acid that is most likely of mixed polyketide synthase/nonribosomal peptide synthase origin. These peptides were purified from a new species of cyanobacteria of the genus Lyngbya, which was isolated from a periphyton mat from the Florida Everglades.
authors: Department of Chemistry and Biochemistry, Florida International University, Miami, Florida 33199, USA.
authors: Tianying
authors: T
authors: An
authors: Thallapuranam Krishnaswamy Suresh
authors: TK
authors: Kumar
authors: Minglei
authors: M
authors: Wang
authors: Li
authors: L
authors: Liu
authors: Jackson O
authors: JO
authors: Lay
authors: Rohana
authors: R
authors: Liyanage
authors: John
authors: J
authors: Berry
authors: Miroslav
authors: M
authors: Gantar
authors: Vered
authors: V
authors: Marks
authors: Robert E
authors: RE
authors: Gawley
authors: Kathleen S
authors: KS
authors: Rein
mesh_terms: D000458:Cyanobacteria / Q000737:chemistry*; D005431:Florida; D005618:Fresh Water; D008235:Lyngbya Toxins / Q000737:chemistry*; D015394:Molecular Structure; D010456:Peptides, Cyclic / Q000737:chemistry*
chemical_list: D008235:Lyngbya Toxins; D010456:Peptides, Cyclic; C509972:pahayokolide A; C520504:pahayokolide B