Frequency-selective quantitation of short-echo time 1H magnetic resonance spectra.
Accurate and efficient filtering techniques are required to suppress large nuisance components present in short-echo time magnetic resonance (MR) spectra. This paper discusses two powerful filtering techniques used in long-echo time MR spectral quantitation, the maximum-phase FIR filter (MP-FIR) and the Hankel-Lanczos Singular Value Decomposition with Partial ReOrthogonalization (HLSVD-PRO), and shows that they can be applied to their more complex short-echo time spectral counterparts. Both filters are validated and compared through extensive simulations. Their properties are discussed. In particular, the capability of MP-FIR for dealing with macromolecular components is emphasized. Although this property does not make a large difference for long-echo time MR spectra, it can be important when quantifying short-echo time spectra.
Poullet
Jean-Baptiste
JB
Department of Electrical Engineering, SCD-SISTA, Katholieke Universiteit Leuven, Kasteelpark Arenberg 10, 3001 Leuven, Belgium. jean-baptiste.poullet@esat.kuleuven.be
Sima
Diana M
DM
Van Huffel
Sabine
S
Van Hecke
Paul
P
D000818:Animals; D016477:Artifacts; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D013997:Time Factors; D014867:Water
D014867:Water