[Observation on acupuncture at "Neitinggong" for antagonisting ototoxicity caused by gentamicin].
OBJECTIVE
To explore the effect of acupuncture at "Neitinggong" drug-induced deafness.


METHODS
Guinea pig deafness model was prepared by injection of gentamicin (GM). Acupuncture was respectively given at the points "Neitinggong" "Tinggong" (SI 19) and non-acupoints on the auricle in the experimental animals in different groups and the effects of different points on the auditory brainstem response and cochlear hair cells were observed.


RESULTS
There was a significant difference between GM group and Neitinggong group, and between GM group and Tinggong group. There was no significant difference between GM group and the auricle group, and between Neitinggong group and Tinggong group.


CONCLUSIONS
Acupuncture at "Neitinggong" can strength the function of the internal ear, and relieve the injury of cochlear hair cells caused by gentamicin, which is an effective acupoint for treatment of drug-induced deafness.
Ma
Wei-jun
WJ
ENT Department of Second Hospital of Xian Jiaotong University, Shaanxi, China.
Xu
Min
M
Zhang
Xiao-tong
XT
Liu
Hui
H
Li
Hong-yue
HY
Zhou
Xiao-hong
XH
D015669:Acupuncture Points; D015670:Acupuncture Therapy; D000818:Animals; D000900:Anti-Bacterial Agents / Q000633:toxicity*; D003051:Cochlea / Q000187:drug effects / Q000473:pathology; D003638:Deafness / Q000139:chemically induced* / Q000517:prevention & control; D016057:Evoked Potentials, Auditory, Brain Stem / Q000187:drug effects; D005260:Female; D005839:Gentamicins / Q000633:toxicity*; D006168:Guinea Pigs; D006198:Hair Cells, Auditory / Q000187:drug effects / Q000473:pathology; D008297:Male
D000900:Anti-Bacterial Agents; D005839:Gentamicins