Aniline-induced methaemoglobinaemia in a glucose-6-phosphate dehydrogenase enzyme deficient patient.
A case of methaemoglobinaemia following ingestion of an aniline-containing material is described. The detrimental effect of methylene blue, the classical antidote of methaemoglobinaemia, in a patient with glucose-6-phosphate dehydrogenase deficiency is highlighted.
Mullick
P
P
Intensive Care Unit, Department of Anaesthesia and Intensive Care, Deen Dayal Upadhyay Hospital, New Delhi, India.
Kumar
A
A
Dayal
M
M
Babbar
S
S
Kumar
A
A
D000328:Adult; D000814:Aniline Compounds / Q000009:adverse effects*; D001784:Blood Gas Analysis / Q000379:methods; D001803:Blood Transfusion / Q000379:methods; D004791:Enzyme Inhibitors / Q000008:administration & dosage; D005260:Female; D005751:Gastric Lavage / Q000379:methods; D005955:Glucosephosphate Dehydrogenase Deficiency / Q000150:complications*; D006461:Hemolysis; D006801:Humans; D007385:Intermittent Positive-Pressure Ventilation / Q000379:methods; D007442:Intubation, Intratracheal / Q000379:methods; D008708:Methemoglobinemia / Q000139:chemically induced* / Q000150:complications / Q000628:therapy; D008751:Methylene Blue / Q000008:administration & dosage; D010092:Oximetry / Q000379:methods; D010100:Oxygen / Q000008:administration & dosage / Q000097:blood
D000814:Aniline Compounds; D004791:Enzyme Inhibitors; D010100:Oxygen; C023650:aniline; D008751:Methylene Blue