title: [Clinical evaluation after an introduction of our manual for antibiotic use during perioperative period and a notification policy of use of the antibiotics for MRSA].
abstract: Abuse of antibiotics results in unfavorable consequences in healthcare associated infection control, such as emergence of multiple-resistant bacteria, and increased medical cost and nosocomial infection. In 2003, we had an outbreak of Methicillin-resistant Staphylococcus aureus (MRSA) in a surgical ward of Akita University Hospital. With the aim of preventing inappropriate use of antibiotics during perioperative period, a guideline for usage of antibiotics, which is made by surgeons themselves, was introduced, and a notification policy of the antibiotic use for MRSA was also applied in 2004. In this study, we evaluated the influence of the antibiotic restriction on changes in antibiotics consumption, prevalence of multiple-drug-resistant pathogens, and their susceptibility to antibiotics. The notification policy reduced the cost and amount of antibiotics and the prevalence of multiple-drug-resistant pathogens, such as MRSA and Pseudomonas aeruginosa. The susceptibility of bacteria, such as Staphylococcus aureus, MRSA, Serratia marcescens and Pseudomonas aeruginosa, to antibiotics showed a remarkable improvement. The introduction of notification policy for usage of antibiotics has a favorable influence on the infection control in hospitals and re education of doctors.
authors: Infection Control Team, Akita University Hospital, Akita.
authors: Wataru
authors: W
authors: Ito
authors: Noriko
authors: N
authors: Kobayashi
authors: Hiroyuki
authors: H
authors: Kayaba
authors: Tomoe
authors: T
authors: Takahashi
authors: Masahide
authors: M
authors: Takeda
authors: Takahito
authors: T
authors: Chiba
authors: Kazutoshi
authors: K
authors: Yamaguchi
authors: Ryouzou
authors: R
authors: Fukui
authors: Noriko
authors: N
authors: Tomita
authors: Junichi
authors: J
authors: Chihara
mesh_terms: D000900:Anti-Bacterial Agents; D003428:Cross Infection / Q000453:epidemiology / Q000517:prevention & control*; D004196:Disease Outbreaks; D017723:Drug Utilization Review / Q000379:methods*; D006801:Humans; D017053:Infection Control / Q000379:methods*; D007564:Japan / Q000453:epidemiology; D008370:Manuals as Topic; D016106:Methicillin Resistance; D019990:Perioperative Care; D017410:Practice Guidelines as Topic; D015995:Prevalence; D013203:Staphylococcal Infections / Q000453:epidemiology / Q000517:prevention & control*; D013211:Staphylococcus aureus; D013997:Time Factors
chemical_list: D000900:Anti-Bacterial Agents