title: Ruthenium-catalyzed sequential reactions: deracemization of secondary benzylic alcohols.
abstract: The deracemization of secondary benzylic alcohols proceeds successfully by a two-step process with the appropriate combination of two different ruthenium complexes for catalysis in the first oxidation and second reduction steps. The sequential catalytic system provides a novel approach to obtaining optically active alcohols, including diols, in high yields with excellent enantioselectivity (up to 95% ee), in contrast to the conventional kinetic resolution of racemic alcohols.
authors: Institute of Engineering Innovation, The University of Tokyo, Yayoi, Bunkyo-ku, Tokyo, 113-8656, Japan.
authors: Yusuke
authors: Y
authors: Shimada
authors: Yoshihiro
authors: Y
authors: Miyake
authors: Hiroshi
authors: H
authors: Matsuzawa
authors: Yoshiaki
authors: Y
authors: Nishibayashi