[The obstetrical and fetal prognosis after metrorrhagia in the first trimester of pregnancy: with reference to 187 cases].
The authors followed 187 pregnancies in which metrorrhagia had occurred in the first trimester, but which had not resulted in abortion. In these patients, the authors studied particularly changes in hormone levels in the urine and the relation between these levels and fetal prognosis. If hormonal deficit is related to fetal prognosis, the relationship does not appear to be a direct one: estrogen deficiency is discovered more often than luteal deficiency; the more serious the estrogen deficiency the more often is it associated with severe progesterone deficiency; The number of fetal malformations did not seem to be any higher in patients who had presented metrorrhagia in first trimester than in patients whose pregnancy was normal. Any higher in patients who had presented metrorrhagia in the pregnancy on one hormone analysis, whether or not it is abnormal. The examinations should be repeated so that the evolution may be followed carefully.
Gellé
P
P
Service de Gynécologie-Obstétrique, Centre Hospitelier, 59100 Roubaix, France.
Crépin
G
G
Delahousse
G
G
Decocq
J
J
Lottin-Marin
C
C
D000328:Adult; D000013:Congenital Abnormalities / Q000145:classification; D004967:Estrogens / Q000172:deficiency / Q000652:urine; D005260:Female; D047109:Fetal Development / Q000502:physiology; D005500:Follow-Up Studies; D005865:Gestational Age; D006801:Humans; D007743:Labor, Obstetric; D007986:Luteinizing Hormone / Q000172:deficiency / Q000652:urine; D008796:Metrorrhagia / Q000150:complications*; D011247:Pregnancy; D011248:Pregnancy Complications; D011256:Pregnancy Outcome; D011261:Pregnancy Trimester, First; D011374:Progesterone / Q000172:deficiency / Q000652:urine; D011379:Prognosis; D012189:Retrospective Studies
D004967:Estrogens; D011374:Progesterone; D007986:Luteinizing Hormone