Oral appliances and functional orthopaedic appliances for obstructive sleep apnoea in children.
BACKGROUND
Apnoea is a breathing disorder marked by the absence of airflow at the nose or mouth. In children, risk factors include adenotonsillar hypertrophy, obesity, neuromuscular disorders and craniofacial anomalies. The most common treatment for obstructive sleep apnoea syndrome (OSAS) in childhood is adenotonsillectomy. This approach is limited by its surgical risks, mostly in children with comorbities and, in some patients, by recurrence that can be associated with craniofacial problems. Oral appliances and functional orthopaedic appliances have been used for patients who have OSAS and craniofacial anomalies because they change the mandible posture forwards and potentially enlarge the upper airway and increase the upper airspace, improving the respiratory function.


OBJECTIVE
To assess the effectiveness of oral appliances or functional orthopaedic appliances for OSAS in children.


METHODS
A sensitive search was developed for the Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library 2005, Issue 3); PubMed (January 1966 to September 2005); EMBASE (1980 to September 2005); Lilacs (1982 to September 2005); BBO-Bibliografia Brasileira de Odontologia (1986 to September 2005); and SciELO (1997 to September 2005). There was no restriction of language or source of information.


METHODS
All randomised or quasi-randomised controlled trials comparing all types of oral and functional orthopaedic appliances with placebo or no treatment, in children 15 years old or younger.


METHODS
reduction of apnoea to less than one episode per hour.


RESULTS
dental and skeletal relationship, sleep parameters improvement, cognitive and phonoaudiologic function, behavioural problems, drop outs and withdrawals, quality of life, side effects (tolerability), economic evaluation.


METHODS
Data were independently extracted by two review authors. Authors were contacted for additional information. Risk ratios with 95% confidence intervals were calculated for all important dichotomous outcomes.


RESULTS
The initial search identified 384 trials. One of them, reporting results from a total of 23 patients, was suitable for inclusion in the review. Data provided in the published report did not answer all the questions from this review, but some of them were, and the presented results favour treatment.


CONCLUSIONS
At present there is no sufficient evidence to state that oral appliances or functional orthopaedic appliances are effective in the treatment of OSAS in children. Oral appliances or functional orthopaedic appliances may be helpful in the treatment of children with craniofacial anomalies which are risk factors for apnoea.
Carvalho
F R
FR
Universidade Federal de São Paulo, Internal Medicine Department, Rua Padre Damaso, 314, Osasco, Centro, Brazil, 06016-010. frcarv@bn.com.br
Lentini-Oliveira
D
D
Machado
M A C
MA
Prado
G F
GF
Prado
L B F
LB
Saconato
H
H
D000293:Adolescent; D002648:Child; D006801:Humans; D017289:Orthodontic Appliances, Functional; D009968:Orthodontic Appliances, Removable; D020181:Sleep Apnea, Obstructive / Q000628:therapy*