Myeloid sarcoma presenting with bilateral proptosis and kidney infiltration.
The authors describe a male infant with a history of transient pancytopenia who developed progressive bilateral proptosis associated with diffuse infiltration of the kidney and normal bone marrow. The histopathological examination of the kidney revealed diffuse infiltration of cells of myeloid origin with monocytic differentiation. Although orbital involvement by myeloid sarcoma, with or without concurrent acute myeloid leukemia, is well known, there are distinctive features in this patient that are not reported in the literature, namely bilateral proptosis and simultaneous presence of bilateral kidney infiltration, which enabled diagnosis.
Janic
Dragana
D
University Children's Hospital, Belgrade, Serbia.
Jovanovic
Nada
N
Dokmanovic
Lidija
L
Brasanac
Dimitrije
D
Smoljanic
Zeljko
Z
Lazic
Jelena
J
Rodic
Predrag
P
D000208:Acute Disease; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D003937:Diagnosis, Differential; D005094:Exophthalmos / Q000175:diagnosis* / Q000188:drug therapy; D006801:Humans; D007223:Infant; D007680:Kidney Neoplasms / Q000175:diagnosis* / Q000188:drug therapy; D007951:Leukemia, Myeloid / Q000175:diagnosis* / Q000188:drug therapy; D017254:Leukemic Infiltration; D008297:Male; D009918:Orbital Neoplasms / Q000175:diagnosis* / Q000188:drug therapy; D014057:Tomography, X-Ray Computed