In my opinion... opioid tolerance.
A commentary on the problem of tolerance to opioids is presented from the perspective of a person with chronic nonmalignant pain. The writer challenges the position of many clinicians and professional societies that tolerance to opioid analgesia usually is not a barrier to effective pain management. Implications for clinicians are presented.
Collen
Mark
M
mark@painexhbit.com
D000701:Analgesics, Opioid / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use; D001291:Attitude of Health Personnel; D004361:Drug Tolerance; D006801:Humans; D009369:Neoplasms; D010146:Pain / Q000188:drug therapy* / Q000209:etiology
D000701:Analgesics, Opioid