title: [Neonatal sepsis in the era of antenatal antibiotic prophylaxis].
abstract: The aim of this study was to compare incidence, bacteriology and associated mortality of neonatal sepsis in a neonatal unit, after (2001-2004) and before (1995-1996) implementation of universal screening for prevention of Group B Streptococcus diseases. Early onset sepsis incidence decreased from 2.5 to 1 per 1000 live births (p=0.03), with a decrease in the proportion of Group B Streptococcus cases from a 54% to 11% (p<0.01). In late onset sepsis, coagulase-negative Staphylococci continued to be the predominant pathogen (49% of cases), and Candida albicans emerged as the second etiologic agent in the postscreening period. Sepsis associated mortality was low in both periods (2.2%).
authors: Unidad de Neonatología, Departamento de Pediatría, Hospital Clínico, Pontificia Universidad Católica de Chile, Santiago, Chile. jlta@med.puc.cl
authors: José Luis
authors: JL
authors: Tapia I
authors: Cristina
authors: C
authors: Reichhard T
authors: M Isabel
authors: MI
authors: Saldías R
authors: Fernando
authors: F
authors: Abarzúa C
authors: M Eugenia
authors: ME
authors: Pérez A
authors: Alvaro
authors: A
authors: González M
authors: Alessandra
authors: A
authors: Gederlini G
mesh_terms: D019072:Antibiotic Prophylaxis; D002677:Chile / Q000453:epidemiology; D005260:Female; D006801:Humans; D015994:Incidence; D007231:Infant, Newborn; D018445:Infectious Disease Transmission, Vertical / Q000517:prevention & control* / Q000706:statistics & numerical data; D007363:Intensive Care Units, Neonatal / Q000706:statistics & numerical data*; D008297:Male; D018805:Sepsis / Q000382:microbiology / Q000401:mortality / Q000517:prevention & control*