[Advances in studies on Platycodon grandiflorum].
Platycodon grandiflorum, as the traditional Chinese medicine, has been employed for dispersing the lung and resolving phlegm soothing the throat, and promoting pus discharge in ancient days. Triterpenoids are its main effective constituents which have dominant activities on antitussive, expectorant, antitumor, antioxidant and immune enhancement. This paper has mainly reviewed the progress of P. grandiflorum on the processing in planting area, chemical constituents, quality standard, pharmacological effects and clinical application in recent ten years, which has provided the important references for its further study, exploitation and application.
Guo
Li
L
Institute of Chinese Materia Medica, China Academy of Chinese Medicial Sciences, Beijing 100700, China.
Zhang
Cun
C
Li
Li
L
Xiao
Yong-qing
YQ
D000818:Animals; D003371:Cough / Q000188:drug therapy; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification* / Q000627:therapeutic use; D006801:Humans; D015394:Molecular Structure; D010612:Pharyngitis / Q000188:drug therapy; D008517:Phytotherapy / Q000379:methods / Q000639:trends; D031238:Platycodon / Q000737:chemistry*; D012503:Saponins / Q000737:chemistry / Q000302:isolation & purification / Q000627:therapeutic use; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000627:therapeutic use
D004365:Drugs, Chinese Herbal; D012503:Saponins; D014315:Triterpenes; C108953:platycodin D