Iris cavernous hemangioma associated with multiple cavernous hemangiomas in the kidney, brain, and skin.
OBJECTIVE
To document the relationship of iris cavernous hemangiomas with multiorgan hemangiomas in a child.


METHODS
A 7-year-old girl with kidney hemangiomas, brain hemangiomas, and skin hemangiomas developed blurred vision and darkening of the right iris. She had undergone 6 previous brain surgeries and multiple revisions of a ventriculoperitoneal shunt for hydrocephalus beginning at age 3 months.


RESULTS
Examination revealed visual acuity of 20/30 in the right eye and 20/20 in the left eye. There was a reddish-purple lobulated cystic mass along the superior iris pupillary margin measuring 2 mm in greatest diameter confirmed by ultrasound biomicroscopy. The remainder of the ocular examination was unremarkable. The diagnosis was iris cavernous hemangioma in a patient with multiorgan cavernous hemangiomatosis. By 1-year follow-up, the iris hemangioma deflated, leaving a fibrotic, involuted scar.


CONCLUSIONS
Iris cavernous hemangioma can be associated with multiorgan hemangiomas that can be life threatening.
Thangappan
Archana
A
Ocular Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, PA, USA.
Shields
Carol L
CL
Dinowitz
Marc
M
Shields
Jerry A
JA
D001932:Brain Neoplasms / Q000473:pathology*; D002648:Child; D005260:Female; D006392:Hemangioma, Cavernous / Q000000981:diagnostic imaging / Q000473:pathology*; D006801:Humans; D015811:Iris Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D007680:Kidney Neoplasms / Q000473:pathology*; D008279:Magnetic Resonance Imaging; D033401:Microscopy, Acoustic; D009378:Neoplasms, Multiple Primary / Q000473:pathology*; D012878:Skin Neoplasms / Q000473:pathology*