[Upper aerodigestive tract carcinoma: therapeutic management].
Cancers of the upper aerodigestive tract cover the solid tumors of the oral cavity, pharynx and larynx. The principal risk factors identified are smoking and alcohol. Moreover, the combination of alcohol and smoking increases the relative risk by more than simple multiplication. The pretreatment work-up represents the starting point in the natural history of the patient's disease and conditions recovery and time course; it must be both specific and exhaustive. It leads to a TNM classification or staging that is a major prognostic factor and essential to determination of the appropriate therapy. Patients with cancer of the upper aerodigestive tract must receive cooperative multidisciplinary treatment. Conservative treatment strategies must be favored. Treatment is essentially surgical and radiological. Prognosis for survival is poor. For all stages and sites together, 5-year survival remains between 30 and 40%.
Poissonnet
Gilles
G
Institut universitaire de la face et du cou de Nice et Centre Antoine-Lacassagne, Nice. gilles.poissonnet@cal.nice.fnclcc.fr
Benezery
Karen
K
Peyrade
Frédéric
F
Bozec
Alexandre
A
Bensadoun
René-Jean
RJ
Marcy
Pierre Yves
PY
Santini
José
J
Dassonville
Olivier
O
D006801:Humans; D007822:Laryngeal Neoplasms / Q000188:drug therapy / Q000532:radiotherapy / Q000601:surgery / Q000628:therapy*; D009062:Mouth Neoplasms / Q000188:drug therapy / Q000532:radiotherapy / Q000601:surgery / Q000628:therapy*; D010610:Pharyngeal Neoplasms / Q000188:drug therapy / Q000532:radiotherapy / Q000601:surgery / Q000628:therapy*