Non-pressure-related effects of dietary sodium.
After the demonstration of a positive correlation between sodium intake and arterial pressure in large population studies, the effect of short-term reduction in sodium intake demonstrated the efficacy of this nonpharmacological therapy. In addition, a positive relation between urinary sodium (the most reliable estimate of salt intake) and left ventricular hypertrophy was found; and in recent years it was shown that cardiovascular morbidity clearly progressed with increasing sodium intake, despite one contradictory study. The role of non-pressure-related effects of dietary sodium is discussed in order to bring more arguments for a large-scale attempt to reduce sodium intake by 30% to 50%.
Cailar
Guilhem du
Gd
Department of Internal Medicine, Hôpital Lapeyronie, Montpellier Cedex 5, France.
Mimran
Albert
A
D000818:Animals; D001794:Blood Pressure / Q000187:drug effects*; D002319:Cardiovascular System / Q000187:drug effects / Q000503:physiopathology*; D004039:Diet, Sodium-Restricted; D006801:Humans; D006973:Hypertension / Q000178:diet therapy / Q000378:metabolism / Q000503:physiopathology; D012307:Risk Factors; D012982:Sodium, Dietary / Q000378:metabolism / Q000494:pharmacology*; D014655:Vascular Resistance / Q000187:drug effects
D012982:Sodium, Dietary