Unilateral lacrimal gland atrophy in a patient with hereditary angioedema.
OBJECTIVE
To report a case of unilateral lacrimal gland atrophy in a patient with hereditary angioedema (HAE).


METHODS
Observational case report with literature review.


RESULTS
A 32-year-old woman with HAE presented with dryness and irritation of the left eye (OS). Investigations revealed features of unilateral severe dry OS with atrophy of the ipsilateral lacrimal gland confirmed by magnetic resonance imaging (MRI).


CONCLUSIONS
Dry eye should be included in the ocular manifestations of HAE. Recurrent mucosal and soft-tissue inflammation secondary to HAE may lead to lacrimal gland atrophy. MRI is a useful, noninvasive tool in diagnosing lacrimal gland atrophy.
Dollin
Michael
M
Faculty of Medicine, University of Toronto, Toronto, Canada.
Srinivasan
Sathish
S
Leith
Eric
E
Slomovic
Allan
A
D000328:Adult; D000799:Angioedema / Q000235:genetics*; D001284:Atrophy; D015352:Dry Eye Syndromes / Q000209:etiology*; D005260:Female; D006801:Humans; D007765:Lacrimal Apparatus / Q000473:pathology*