[Effect of Shenfu injection in postoperative recovery after abdominal surgery].
OBJECTIVE
To investigate the effect of Shenfu injection (SF) in postoperative recovery after abdominal surgery.


METHODS
150 patients were randomly divided into control group (75) and SF group (75). The efficacy were evaluated with the time of passage of gas by anus, information of wound healing, blood routine, blood coagulaton function, liver function. Changes recovery factor, immune index and hemorheological index were detected too.


RESULTS
The time of passage of gas by anus in SF group was significantly shorter than that in control group. Blood routine, blood coagulaton function, liver function showed no significant difference in the two group of preoperative and postoperative. Whole blood viscosity, blood reduced viscosity and plasma fibrinogen viscosity in SF group were significantly lower than that in control group after operation. IgG and IgA in SF group was significantly higher than that in control group after operation. IgG and CD4+/CD8+ in control group was significantly higher after operation than that in before operation. Among tissue damage plerosis correlation factor, the blood levels of superoxide dismutase (SOD) in SF group and control group is significantly lower than that in preoperation (P < 0.05), SOD in SF group was significantly higher than that in control group after operation. The blood levels of malondialdehyde (MDA) in SF group and control group is significantly higher than that in preoperation (P < 0.05). MDA in SF group was significantly lower than that in control group after operation. Whole blood viscosity, blood reduced viscosity and plasma fibrinogen viscosity in control group after operation were significantly higher than that before operation.


CONCLUSIONS
SF can stimulate the immune system and reduce the blood viscosity. It is contribute to the patients' rehabilitation.
Zhou
Qi
Q
The 1st Affiliated Hospital of Zhongshan University, Guangzhou 510080, China. hnzhouqi@163.com
Liang
Li-Jian
LJ
Zhang
Liang
L
Zhen
Yu-Yang
YY
Su
Cai-Kun
CK
D031841:Aconitum / Q000737:chemistry; D000328:Adult; D000368:Aged; D015703:Antigens, CD / Q000097:blood; D001809:Blood Viscosity / Q000187:drug effects; D002763:Cholecystectomy; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage / Q000627:therapeutic use*; D005260:Female; D006498:Hepatectomy / Q000379:methods; D006801:Humans; D007262:Infusions, Intravenous; D008297:Male; D008315:Malondialdehyde / Q000097:blood; D008875:Middle Aged; D005894:Panax / Q000737:chemistry; D008517:Phytotherapy; D010946:Plants, Medicinal / Q000737:chemistry*; D011182:Postoperative Care; D020127:Recovery of Function / Q000187:drug effects*; D013482:Superoxide Dismutase / Q000097:blood
D015703:Antigens, CD; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal; C492793:Shen-Fu; D008315:Malondialdehyde; D013482:Superoxide Dismutase