Kluver-Bucy syndrome--a rare complication of herpes simplex encephalitis.
A twelve-year-old female was admitted with history of high fever, recurrent vomiting and repeated convulsion for 2 days and altered consciousness for one day. Cranial CT scan showed intraparenchymal haemorrhage involving both temporal lobes and right basal ganglia region without mass effect. Serology was reactive against IGM HSV1. Injection acyclovir was started at a dose of 10 mg/kg 8 hourly intravenously. Patient regained consciousness on fourth day but speech was altered. Abnormal behavioural symptoms were noticed. EEG showed generalised spike and slow waves and sharp and slow wave discharge more in the temporal region. The patient was given clonidine and carbamazepine. She also received behavioural therapy and parental counselling. She was followed up for six months and maintaining well.
Begum
Hosenara
H
Department of Paediatrics, Medical College, Kolkata.
Nayek
Kaustav
K
Khuntdar
Bidyut Kr
BK
D000212:Acyclovir / Q000627:therapeutic use; D000998:Antiviral Agents / Q000627:therapeutic use; D002220:Carbamazepine / Q000627:therapeutic use; D002648:Child; D003000:Clonidine / Q000627:therapeutic use; D020803:Encephalitis, Herpes Simplex / Q000150:complications*; D005260:Female; D006801:Humans; D020232:Kluver-Bucy Syndrome / Q000188:drug therapy / Q000209:etiology*; D012307:Risk Factors
D000998:Antiviral Agents; D002220:Carbamazepine; D003000:Clonidine; D000212:Acyclovir