title: Multiple gangliogliomas of the optic pathway.
abstract: We report a case of multiple gangliogliomas of the optic pathway in an 18-year-old boy. He presented with visual disturbance mainly in his left eye, non-specific headaches, and episodes of sensory disturbance in his left arm. Visual acuity was 6/9 and 6/24 in his right and left eye respectively. He did not have any Lisch nodules. Optic atrophy was noted in his left eye. MRI scan revealed multiple enhancing lesions involving the optic chiasm, left optic tract, right lateral geniculate body, and right optic radiation in the temporal lobe. Stereotactic biopsy of the temporal tumour confirmed ganglioglioma. Multiple gangliogliomas of the optic pathway has not been hitherto described.
authors: Department of Neurosurgery, Wessex Neurological Centre, Southampton General Hospital, Southampton, UK.
authors: G V
authors: GV
authors: Vajramani
authors: S
authors: S
authors: Dambatta
authors: M
authors: M
authors: Walker
authors: P L
authors: PL
authors: Grundy
mesh_terms: D000293:Adolescent; D018906:Antineoplastic Agents, Alkylating / Q000627:therapeutic use; D001932:Brain Neoplasms / Q000175:diagnosis* / Q000628:therapy; D003606:Dacarbazine / Q000031:analogs & derivatives / Q000627:therapeutic use; D018303:Ganglioglioma / Q000175:diagnosis* / Q000628:therapy; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D019574:Optic Nerve Neoplasms / Q000175:diagnosis* / Q000628:therapy; D000077204:Temozolomide; D016896:Treatment Outcome; D014786:Vision Disorders / Q000209:etiology*
chemical_list: D018906:Antineoplastic Agents, Alkylating; D003606:Dacarbazine; D000077204:Temozolomide