Anterior segment optical coherence tomography imaging of trabeculectomy blebs before and after laser suture lysis.
OBJECTIVE
To image trabeculectomy blebs before and after laser suture lysis (LSL) using anterior segment optical coherence tomography (AS-OCT).


METHODS
Prospective observational study.


METHODS
Blebs were imaged with a prototype of the AS-OCT (Carl Zeiss Meditec, Inc, Dublin, California, USA) before and after LSL. Blebs were assessed for bleb height, bleb wall thickness, apposition of the scleral flap to sclera, and patency of the internal ostium.


RESULTS
Seven blebs in eyes of seven patients were imaged. Pre-LSL, five blebs were low and two were of moderate height. After LSL, six of seven eyes (85.7%) showed an increase in total bleb height, with increased bleb wall thickness and separation of the scleral flap from sclera. In one eye, there was no discernible change in bleb height, cavity height, or wall thickness.


CONCLUSIONS
AS-OCT was able to demonstrate features of bleb morphology that changed after LSL.
Singh
Mandeep
M
National University Hospital, Singapore.
Aung
Tin
T
Friedman
David S
DS
Zheng
Ce
C
Foster
Paul J
PJ
Nolan
Winifred P
WP
See
Jovina L
JL
Smith
Scott D
SD
Chew
Paul T K
PT
D000368:Aged; D000869:Anterior Eye Segment / Q000473:pathology*; D001768:Blister / Q000175:diagnosis*; D015812:Glaucoma, Angle-Closure / Q000601:surgery; D005902:Glaucoma, Open-Angle / Q000601:surgery; D006801:Humans; D007429:Intraocular Pressure; D053685:Laser Therapy; D011446:Prospective Studies; D012590:Sclera / Q000601:surgery; D013524:Surgical Flaps; D013536:Suture Techniques; D041623:Tomography, Optical Coherence; D014130:Trabeculectomy