Molecular epidemiology and clinical manifestations of viral gastroenteritis in hospitalized pediatric patients in Northern Taiwan.
By reverse transcription-PCR or PCR, among 257 children with nonbacterial acute gastroenteritis (AGE), rotavirus, norovirus, astrovirus, enteric adenovirus, and multiple viruses were identified in 78 (30.4%), 21 (8.2%), 7 (2.7%), 51 (19.8%), and 53 (20.6%) patients, respectively. Higher disease severity was found for AGE caused by multiple viruses and by rotavirus alone. The majority of rotaviruses isolated from 2004 to 2006 belonged to genotypes G1 (20.4%), G2 (16.5%), G3 (27.2%), and G9 (21.4%).
Chen
Shih-Yen
SY
Division of Pediatric Gastroenterology, Chang Gung University College of Medicine, Kweishan 333, Taoyuan, Taiwan.
Chang
Yu-Chung
YC
Lee
Yun-Shien
YS
Chao
Hsun-Chin
HC
Tsao
Kuo-Chien
KC
Lin
Tzou-Yien
TY
Ko
Tzu-Yin
TY
Tsai
Chi-Neu
CN
Chiu
Cheng-Hsun
CH
D002675:Child, Preschool; D005243:Feces / Q000821:virology; D005260:Female; D005759:Gastroenteritis / Q000453:epidemiology / Q000503:physiopathology / Q000821:virology; D006760:Hospitalization; D006801:Humans; D007223:Infant; D008297:Male; D017720:Molecular Epidemiology; D012401:Rotavirus / Q000145:classification / Q000235:genetics / Q000302:isolation & purification; D012400:Rotavirus Infections / Q000453:epidemiology / Q000503:physiopathology / Q000821:virology; D012621:Seasons; D012720:Severity of Illness Index; D013624:Taiwan / Q000453:epidemiology; D014777:Virus Diseases / Q000453:epidemiology / Q000503:physiopathology / Q000821:virology; D014780:Viruses / Q000145:classification / Q000235:genetics / Q000302:isolation & purification