title: Effects of juvenile hormone and 20-hydroxyecdysone on alkaline phosphatase activity in Drosophila under normal and heat stress conditions.
abstract: The effect of 20-hydroxyecdysone (20E) and the juvenile hormone (JH) on the activity of the alkaline phosphatase (ALP) has been studied in young females of wild-type Drosophila virilis and Drosophila melanogaster under normal conditions and under heat stress (38 degrees C). Both 20E feeding of the flies and JH application led to a substantial rise in ALP activity. ALP activity was also measured in young females of a JH-deficient strain of D. melanogaster, apterous(56f). A decrease in the enzyme activity was observed in the mutant females as compared to wild type. A rise in JH and 20E levels was found not to prevent the response of ALP to heat stress, but to change its stress-reactivity. Mechanisms of regulation of dopamine (DA) level by gonadotropins in Drosophila are discussed.
authors: Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences, Novosibirsk 630090, Russia. irauschen@bionet.nsc.ru
authors: I Yu
authors: IY
authors: Rauschenbach
authors: E V
authors: EV
authors: Bogomolova
authors: N E
authors: NE
authors: Gruntenko
authors: N V
authors: NV
authors: Adonyeva
authors: N A
authors: NA
authors: Chentsova
mesh_terms: D000469:Alkaline Phosphatase / Q000378:metabolism*; D000818:Animals; D004298:Dopamine / Q000378:metabolism; D004331:Drosophila melanogaster / Q000187:drug effects* / Q000201:enzymology* / Q000378:metabolism; D004441:Ecdysterone / Q000494:pharmacology*; D005260:Female; D006358:Hot Temperature; D007605:Juvenile Hormones / Q000494:pharmacology*
chemical_list: D007605:Juvenile Hormones; D004441:Ecdysterone; D000469:Alkaline Phosphatase; D004298:Dopamine