Microbiaeratin, a new natural indole alkaloid from a Microbispora aerata strain, isolated from Livingston Island, Antarctica.
A new sulphur-containing natural alkaloid named microbiaeratin (1a) was isolated, together with the known microbiaeratinin (2, bacillamide) from the culture filtrate of Microbispora aerata strain IMBAS-11A. The organism was isolated from penguin excrements collected on the Antarctic Livingston Island. The structure was elucidated by one- and two-dimensional NMR experiments and mass spectrometric investigations.
Ivanova
Veneta
V
The Stephan Angeloff Institute of Microbiology, Bulgarian Academy of Sciences, Sofia, Bulgaria. venibiva@microbio.bas.bg
Kolarova
Mariana
M
Aleksieva
Krasja
K
Gräfe
Udo
U
Dahse
Hans-Martin
HM
Laatsch
Hartmut
H
D000192:Actinomycetales / Q000737:chemistry* / Q000235:genetics / Q000502:physiology; D000818:Animals; D000864:Antarctic Regions; D001419:Bacteria / Q000187:drug effects* / Q000254:growth & development; D045744:Cell Line, Tumor / Q000187:drug effects; D002851:Chromatography, High Pressure Liquid; D005243:Feces / Q000737:chemistry / Q000382:microbiology; D005347:Fibroblasts / Q000166:cytology / Q000187:drug effects*; D006801:Humans; D026121:Indole Alkaloids / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D051379:Mice; D015394:Molecular Structure; D013057:Spectrum Analysis; D046429:Spheniscidae; D013455:Sulfur / Q000737:chemistry
D026121:Indole Alkaloids; C521080:microbiaeratin; D013455:Sulfur