Atypical neurothekeoma: a new case and review of the literature.
BACKGROUND
Neurothekeoma is a rare neoplasm ascribed into the broad category of benign peripheral nerve sheath tumors. The atypical cellular variant of this neoplasm, showing a peculiar histological pattern, has been very rarely reported in literature.


METHODS
The clinical, histopathological and immunohistochemical profile of a new case of atypical cellular neurothekeoma in a 32-year-old woman is reported.


RESULTS
The described neoplasm showed the histological features of atypical variant of cellular neurothekeoma with high-rate mitotic activity and deep penetration into subcutaneous fat.


CONCLUSIONS
Because only few cases of atypical neurothekeoma have been reported in literature, clinical and morphological available data on this neoplasm are very few, and its prognosis remains uncertain; anyway, dermatologists should be aware of histological features of this neoplasm for which a complete surgical excision is recommended.
Campanati
Anna
A
Dermatological Department, Marche Polytechnic University, Ancona, Italy. a.campanati@ao-umbertoprimo.marche.it
Brandozzi
Giuliano
G
Sisti
Stefano
S
Bernardini
Maria Luisa
ML
Offidani
Anna Maria
AM
D000328:Adult; D002680:Chin / Q000473:pathology*; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D018321:Neurothekeoma / Q000378:metabolism / Q000473:pathology*; D012983:Soft Tissue Neoplasms / Q000378:metabolism / Q000473:pathology*