Preparation of chitosan nanofiber tube by electrospinning.
Water-insoluble chitosan nanofiber sheets and tubes coated with chitosan-cast film were prepared by electrospinning. When as-spun chitosan nanofiber sheets and tubes were immersed in 28% ammonium aqueous solution, they became insoluble in water and showed nanofiber structures confirmed by SEM micrography. Mechanical properties of chitosan nanofiber sheets and tubes were improved by coating with chitosan-cast film, which gave them a compressive strength higher than that of crab-tendon chitosan, demonstrating that chitosan nanofiber tubes coated with chitosan-cast film are usable as nerve-regenerative guide tubes.
Matsuda
Atsushi
A
Creative Research Initiative "Sousei," Hokkaido University, Sapporo, Hokkaido 001-0021, Japan.
Kagata
Go
G
Kino
Rikako
R
Tanaka
Junzo
J
D000818:Animals; D001696:Biomechanical Phenomena; D048271:Chitosan / Q000737:chemistry*; D020099:Coated Materials, Biocompatible / Q000737:chemistry; D019245:Compressive Strength; D004563:Electrochemistry; D008422:Materials Testing; D008855:Microscopy, Electron, Scanning; D036103:Nanotechnology; D043942:Nanotubes / Q000737:chemistry* / Q000648:ultrastructure; D009416:Nerve Regeneration; D012995:Solubility; D023822:Tissue Engineering; D014867:Water
D020099:Coated Materials, Biocompatible; D014867:Water; D048271:Chitosan