title: Evaluation of hypertensive cardiac abnormalities using the Cornell product.
abstract: BACKGROUND
  The Cornell product (CP) improved identification of left ventricular hypertrophy (LVH) in the LIFE study, although its clinical significance is still unknown in Japanese hypertensive (HT) patients.
  
  
  RESULTS
  A standard 12-lead ECG was recorded in 265 HT and 363 normotensive cases (N). All ECGs were digitized, and a simple product was calculated by multiplying the Cornell voltage (CV) by the QRS duration. In 147 of the 265 HT cases, the standard 12-lead ECG and transthoracic Doppler echocardiography were examined in the same period. The mean value of CP increased in the following order: 1,426+/-673 mm x ms in N, 1,989+/-900 mm x ms in HT with treatment, 2,137+/-976 mm x ms in HT without treatment. The correlation with left ventricular mass index (LVMI) measured by echocardiography was improved by CP with the simple CV. With use of a partition of 2,440 mm x ms in CP, LVMI and relative wall thickness were significantly higher in HT with > or =2,440 mm x ms of CP compared with <2,440 mm x ms. Early diastolic wave in tissue Doppler imaging was significantly lower in HT with > or =2,440 mm x ms of CP compared with <2,440 mm x ms.
  
  
  CONCLUSIONS
  The Cornell product is a useful ECG marker, reflecting not only left ventricular (LV) mass but also LV geometry and diastolic function in Japanese HT patients.
authors: Cardiovascular Disease Center, Tokyo Metropolitan Police Hospital, Chiyoda-ku, Tokyo, Japan. shirai@keisatsubyoin.or.jp
authors: Tetsuro
authors: T
authors: Shirai
authors: Masashi
authors: M
authors: Kasao
authors: Miho
authors: M
authors: Nozaki
authors: Syuuya
authors: S
authors: Nitta
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D044466:Asian People; D004452:Echocardiography / Q000592:standards; D015150:Echocardiography, Doppler / Q000592:standards; D004562:Electrocardiography / Q000379:methods* / Q000592:standards*; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications*; D017379:Hypertrophy, Left Ventricular / Q000175:diagnosis* / Q000208:ethnology / Q000209:etiology*; D008297:Male; D008875:Middle Aged