title: Effects of reconcile (fluoxetine) chewable tablets plus behavior management for canine separation anxiety.
abstract: Canine separation anxiety is a common behavioral problem presented to veterinarians. Associated behaviors are distressing to both dog and owner, have the potential to disrupt the human-companion animal bond, and may lead to euthanasia. The results of this study demonstrate the clinical efficacy and safety of Reconcile (fluoxetine, 1 to 2 mg/kg/day [0.45 to 0.91 mg/lb/day]), in conjunction with behavior management, for the treatment of canine separation anxiety. The beef flavored chewable formulation was palatable to treated dogs and easy to administer. This study provides to veterinarians and owners valuable information about an effective separation anxiety treatment plan that combines use of Reconcile with behavior modification.
authors: Veterinary Behavior Clinic, Southern Pines, NC 28387, USA.
authors: Barbara Sherman
authors: BS
authors: Simpson
authors: Gary M
authors: GM
authors: Landsberg
authors: Ilana R
authors: IR
authors: Reisner
authors: John J
authors: JJ
authors: Ciribassi
authors: Debra
authors: D
authors: Horwitz
authors: Katherine A
authors: KA
authors: Houpt
authors: Tracy L
authors: TL
authors: Kroll
authors: Andrew
authors: A
authors: Luescher
authors: Kelly S
authors: KS
authors: Moffat
authors: Genefer
authors: G
authors: Douglass
authors: Carol
authors: C
authors: Robertson-Plouch
authors: Melissa F
authors: MF
authors: Veenhuizen
authors: Alan
authors: A
authors: Zimmerman
authors: Terrence P
authors: TP
authors: Clark
mesh_terms: D000284:Administration, Oral; D000818:Animals; D018687:Antidepressive Agents, Second-Generation / Q000008:administration & dosage*; D001010:Anxiety, Separation / Q000188:drug therapy* / Q000523:psychology; D001522:Behavior, Animal; D002170:Canada; D004283:Dog Diseases / Q000188:drug therapy* / Q000523:psychology; D004285:Dogs; D004311:Double-Blind Method; D005473:Fluoxetine / Q000008:administration & dosage*; D001841:Human-Animal Bond; D006801:Humans; D017367:Selective Serotonin Reuptake Inhibitors / Q000008:administration & dosage*; D016896:Treatment Outcome; D014481:United States
chemical_list: D018687:Antidepressive Agents, Second-Generation; D005473:Fluoxetine; D017367:Selective Serotonin Reuptake Inhibitors