Laryngopharyngeal reflux and chronic sinusitis.
In patients with chronic and recurrent sinusitis, laryngopharyngeal reflux disease may play a significant role. Laryngopharyngeal reflux disease differs from gastroesophageal reflux disease in the extent of reflux (into the hypopharynx and above) as well as timing (occurring more often when the patient is upright). Most patients are unaware of the extent of their symptoms, and diagnostic tools such as pH probe, multichannel intraluminal impedance, and manometry are required for adequate diagnosis. Although therapy with lifestyle modification and acid-suppressive agents may improve reflux in the majority of patients, for many with persistent symptoms, endoscopic or surgical intervention is required to reduce reflux successfully.
Weldon
David
D
Scott and White Clinic, 1600 University Drive East, College Station, TX 77845, USA. dweldon@swmail.sw.org
D000863:Antacids / Q000627:therapeutic use; D000897:Anti-Ulcer Agents / Q000627:therapeutic use; D002648:Child; D002908:Chronic Disease; D005745:Gastric Acidity Determination; D005764:Gastroesophageal Reflux / Q000150:complications / Q000503:physiopathology / Q000628:therapy; D006635:Histamine H2 Antagonists / Q000627:therapeutic use; D006801:Humans; D007818:Laryngeal Diseases / Q000150:complications / Q000503:physiopathology / Q000628:therapy; D010608:Pharyngeal Diseases / Q000150:complications / Q000503:physiopathology / Q000628:therapy; D012852:Sinusitis / Q000150:complications / Q000503:physiopathology
D000863:Antacids; D000897:Anti-Ulcer Agents; D006635:Histamine H2 Antagonists