title: Cucurbitane triterpenoids from Momordica charantia.
abstract: Three new cucurbitane-type triterpenoid saponins, 23-O-beta-D-allopyranosyl-5beta,19-epoxycucurbita-6,24-diene-3beta,22(S),23(S)-triol-3-O-beta-D-glucopyranoside (1), 23-O-beta-D-allopyranosyl-5beta,19-epoxycucurbita-6,24-diene-3beta,22(S),23(S)-triol-3-O-beta-D-allopyranoside (2), and 23-O-beta-D-allopyranosyl-5beta,19-epoxycucurbita-6,24-diene-3beta,19(R), 22(S),23(S)-tetraol-3-O-beta-D-allopyranoside (3), named momordicoside M, N, and O, respectively, along with one known saponin momordicoside L (4), were isolated from the fresh fruits of Momordica charantia. The structures of these saponins were elucidated on the basis of chemical properties and spectral data.
authors: Department of Natural Medicine, School of Pharmaceutical Sciences, Peking University Health Science Center, No. 38 Xueyuan Road, Beijing 100083, PR China.
authors: Qing-Yan
authors: QY
authors: Li
authors: Hu-Biao
authors: HB
authors: Chen
authors: Zhen-Ming
authors: ZM
authors: Liu
authors: Bin
authors: B
authors: Wang
authors: Yu-Ying
authors: YY
authors: Zhao
mesh_terms: D002247:Carbon Isotopes; D000431:Ethanol / Q000737:chemistry; D005638:Fruit / Q000737:chemistry*; D006027:Glycosides / Q000737:chemistry*; D006859:Hydrogen; D007004:Hypoglycemic Agents / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D008958:Models, Molecular; D008968:Molecular Conformation; D015394:Molecular Structure; D029777:Momordica charantia / Q000737:chemistry*; D012503:Saponins / Q000737:chemistry*; D012997:Solvents / Q000737:chemistry; D014315:Triterpenes / Q000737:chemistry*
chemical_list: D002247:Carbon Isotopes; D006027:Glycosides; D007004:Hypoglycemic Agents; D012503:Saponins; D012997:Solvents; D014315:Triterpenes; C514277:cucurbitane; C522769:momordicoside L; C522111:momordicoside M; C522110:momordicoside N; C522112:momordicoside O; D000431:Ethanol; D006859:Hydrogen