The proton inventory technique in a dual mechanistic system: the spontaneous hydrolysis of ethyl formate.
Ethyl formate undergoes spontaneous hydrolysis through two parallel mechanistic pathways: water catalysis and specific hydrogen-ion catalysis. The proton inventory of the water reaction at 37.0 ( degrees )C was determined from the overall conversion curves, in H(2)O/D(2)O mixtures of deuterium atom fraction n, resulting in k(1)(n)=(2.1+/-0.1)x10(-5) s(-1) (1-n+0.42 n) (1-n+0.83 n)(2), in agreement with the results of six other cases of carboxylic acid derivatives. This result contributes to the validation of the accuracy of the proton inventory technique.
Mata-Segreda
Julio F
JF
Laboratory of Bio-organic Chemistry, School of Chemistry, University of Costa Rica. jmata@cariari.ucr.ac.cr
D002384:Catalysis; D002627:Chemistry, Physical / Q000379:methods*; D003903:Deuterium; D005563:Formic Acid Esters / Q000737:chemistry*; D006868:Hydrolysis; D007554:Isotopes; D007700:Kinetics; D011522:Protons; D014867:Water / Q000737:chemistry
D005563:Formic Acid Esters; D007554:Isotopes; D011522:Protons; D014867:Water; C510888:ethyl formate; D003903:Deuterium