First total synthesis and assignment of the stereochemistry of crispatenine.
The first racemic and enantioselective synthesis of crispatenine 1 has been achieved, which involved a few steps, enabling the assignment of the absolute and relative configurations.
Bourdron
Julien
J
UMR-CNRS 6178 SymBio, équipe Synthèse par voie Organométallique, Université Paul Cézanne (Aix-Marseille III), Avenue Escadrille Normandie Niemen, service 532, 13397 Marseille cedex 20, France.
Commeiras
Laurent
L
Audran
Gérard
G
Vanthuyne
Nicolas
N
Hubaud
J C
JC
Parrain
Jean-Luc
JL
D001688:Biological Products / Q000737:chemistry; D002070:Butadienes / Q000138:chemical synthesis* / Q000737:chemistry; D018360:Crystallography, X-Ray; D003510:Cyclohexanes / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D009930:Organic Chemicals / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
D001688:Biological Products; D002070:Butadienes; D003510:Cyclohexanes; D009930:Organic Chemicals; C520706:crispatenine