title: Clinical and laboratory features of neuromyelitis optica with oligoclonal IgG bands.
abstract: Of 23 neuromyelitis optica (NMO) cases, we found two cases with oligoclonal IgG bands (OBs). Both patients were positive for NMO-IgG. Their common features were long disease duration and co-existing autoimmune diseases (myasthenia gravis and sicca syndrome). Although OBs are mostly negative in NMO, which distinguishes it from multiple sclerosis (MS), they can be positive by long-standing autoimmunity, which may not be directly related to NMO.
authors: Department of Neurology, Tohoku University School of Medicine, Aoba-ku, Sendai 980-8574, Japan. mnakamura@em.neurol.med.tohoku.ac.jp
authors: M
authors: M
authors: Nakamura
authors: I
authors: I
authors: Nakashima
authors: S
authors: S
authors: Sato
authors: I
authors: I
authors: Miyazawa
authors: K
authors: K
authors: Fujihara
authors: Y
authors: Y
authors: Itoyama
mesh_terms: D000368:Aged; D001327:Autoimmune Diseases / Q000276:immunology; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis* / Q000097:blood*; D008279:Magnetic Resonance Imaging; D009471:Neuromyelitis Optica / Q000276:immunology*; D012189:Retrospective Studies; D013116:Spinal Cord / Q000473:pathology
chemical_list: D007074:Immunoglobulin G