title: Sulfonylurea-responsive diabetes in childhood.
abstract: We describe a family in which 3/6 siblings had transient, relapsing neonatal diabetes. The father and another sibling had diabetes diagnosed at 20 and 9 years old, respectively. All affected individuals carried the same KCNJ11 gene mutation. In all, sulfonylurea treatment permitted cessation of insulin treatment, with improved glycemic control.
authors: Diabetes Unit, E. Wolfson Medical Center, Holon, Israel.
authors: Zohar
authors: Z
authors: Landau
authors: Julio
authors: J
authors: Wainstein
authors: Aaron
authors: A
authors: Hanukoglu
authors: Myriam
authors: M
authors: Tuval
authors: Judith
authors: J
authors: Lavie
authors: Benjamin
authors: B
authors: Glaser
mesh_terms: D000328:Adult; D002648:Child; D003920:Diabetes Mellitus / Q000188:drug therapy* / Q000235:genetics; D005260:Female; D005905:Glyburide / Q000627:therapeutic use*; D006801:Humans; D007004:Hypoglycemic Agents / Q000627:therapeutic use*; D007231:Infant, Newborn; D008297:Male; D009154:Mutation; D010375:Pedigree; D024661:Potassium Channels, Inwardly Rectifying / Q000235:genetics; D013453:Sulfonylurea Compounds / Q000627:therapeutic use; D000099161:Kcnj11 Channel
chemical_list: D005905:Glyburide; D007004:Hypoglycemic Agents; D024661:Potassium Channels, Inwardly Rectifying; D013453:Sulfonylurea Compounds; D000099161:Kcnj11 Channel