The effects of superoxide dismutase on H2O2 formation.
Numerous reports of the effects of overproduction of SODs have been explained on the basis of increased H2O2 production by the catalyzed dismutation of O2-. In this review we consider the effects of increasing [SOD] on H2O2 formation and question this explanation.
Liochev
Stefan I
SI
Department of Biochemistry, Duke University Medical Center, Durham, NC 27710, USA.
Fridovich
Irwin
I
D006861:Hydrogen Peroxide / Q000378:metabolism*; D013482:Superoxide Dismutase / Q000378:metabolism*
D006861:Hydrogen Peroxide; D013482:Superoxide Dismutase