Simultaneously acute hepatitis B virus and C virus coinfection and subsequent chronic hepatitis C.
Hepatitis C virus (HCV) and hepatitis B virus (HBV) share similar transmission routes, but concurrent acute HCV and HBV infection was rarely reported. Little is known about viral interaction and hepatic biochemical features of acute HBV and HCV coinfection. We report an intravenous drug abuser with simultaneous acute HBV and HCV infections presenting as biphasic elevation of both alanine aminotransferase (ALT) and total bilirubin levels. HCV infection is the major cause of continuing hepatitis after termination of HBsAg antigenemia.
Chen
Shuo-Wei
SW
Liver Research Unit, Department of Pathology, Chang-Gung Memorial Hospital and Institute of Technology, Keelung, Taiwan.
Lee
Tsung-Shih
TS
Hu
Ching-Chih
CC
Chang
Liang-Che
LC
Chien
Rong-Nan
RN
D000328:Adult; D000410:Alanine Transaminase / Q000097:blood; D001663:Bilirubin / Q000097:blood; D006509:Hepatitis B / Q000097:blood / Q000150:complications* / Q000276:immunology; D006510:Hepatitis B Antibodies / Q000097:blood; D006513:Hepatitis B e Antigens / Q000097:blood; D006526:Hepatitis C / Q000097:blood / Q000150:complications* / Q000276:immunology; D018937:Hepatitis C Antibodies / Q000097:blood; D019698:Hepatitis C, Chronic / Q000209:etiology* / Q000276:immunology; D006801:Humans; D008297:Male; D015819:Substance Abuse, Intravenous / Q000821:virology*
D006510:Hepatitis B Antibodies; D006513:Hepatitis B e Antigens; D018937:Hepatitis C Antibodies; D000410:Alanine Transaminase; D001663:Bilirubin