[Hepatitis E virus infection in population of non-remunerate blood donors in Shaoxing].
OBJECTIVE
To investigate the incidence of HEV infection in population of non-remunerate blood donors in Shaoxing.


METHODS
Blood specimens from 3701 non-remunerate blood donors were collected, ELISA were used to study anti-HEV IgG and IgM antibodies, RT-PCR were further used to study HEV RNA in samples from donors whose anti-HEV IgM was positive.


RESULTS
Anti-HEV IgG positive rate was 29.19% (1107/3701), anti-HEV IgM positive rate was 1.35% (50/3701) among non-remunerate blood donors in Shaoxin. Six cases were positive for HEV RNA. The positive rate was 0.16% (6/3701), and all the 6 cases belonged to HEV genotype 1. Different seasons showed no interference on the positive rate of IgG and IgM.


CONCLUSIONS
The detecting and studying of HEV infection among donors was important to ensure the safety of blood products and blood transfusion.
Sang
Lie-yong
LY
Shaoxing Blood Center, Shaoxing 312041, China.
Zhuang
Pei-fen
PF
Fu
Li-qiang
LQ
Liu
Yi
Y
Ge
Sheng-xiang
SX
Zhang
Jun
J
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D001782:Blood Donors; D002681:China / Q000453:epidemiology; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D016751:Hepatitis E / Q000097:blood* / Q000453:epidemiology / Q000821:virology; D016752:Hepatitis E virus / Q000145:classification / Q000235:genetics* / Q000276:immunology; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D007075:Immunoglobulin M / Q000097:blood; D008297:Male; D008875:Middle Aged; D010802:Phylogeny; D012367:RNA, Viral / Q000097:blood / Q000235:genetics; D020133:Reverse Transcriptase Polymerase Chain Reaction; D055815:Young Adult
D007074:Immunoglobulin G; D007075:Immunoglobulin M; D012367:RNA, Viral