title: Lack of differences of motorcortical excitability in the morning as compared to the evening in juvenile myoclonic epilepsy--a study using transcranial magnetic stimulation.
abstract: We used transcranial magnetic stimulation (TMS) in patients with juvenile myoclonic epilepsy (JME) and healthy controls to characterise motorcortical excitability in the morning as compared to the evening. Intra- and interindividual comparisons in JME-patients and controls showed no significant differences of any TMS parameter. The expected rise of the resting motor thresholds (RMT) in JME-patients taking anticonvulsants could not be detected which may indicate a decreased RMT in JME-patients.
authors: Interdisciplinary Epilepsy Center, Department of Neurology, Philipps-University Marburg, Marburg, Germany. pfuetze@med.uni-marburg.de
authors: Martin
authors: M
authors: Pfütze
authors: Janine
authors: J
authors: Reis
authors: Anja
authors: A
authors: Haag
authors: Daniel
authors: D
authors: John
authors: Katja
authors: K
authors: Hattemer
authors: Wolfgang H
authors: WH
authors: Oertel
authors: Felix
authors: F
authors: Rosenow
authors: Hajo M
authors: HM
authors: Hamer
mesh_terms: D000293:Adolescent; D000328:Adult; D000927:Anticonvulsants / Q000627:therapeutic use; D002940:Circadian Rhythm / Q000502:physiology*; D004569:Electroencephalography; D004832:Epilepsy, Absence / Q000503:physiopathology; D004830:Epilepsy, Tonic-Clonic / Q000503:physiopathology; D005260:Female; D006801:Humans; D008297:Male; D009044:Motor Cortex / Q000503:physiopathology*; D020190:Myoclonic Epilepsy, Juvenile / Q000503:physiopathology*; D050781:Transcranial Magnetic Stimulation
chemical_list: D000927:Anticonvulsants