Birth after intracytoplasmic sperm injection with use of testicular sperm from men with Kartagener or immotile cilia syndrome.
OBJECTIVE
To describe a case of intracytoplasmic sperm injection (ICSI) with testicular sperm in men with immotile cilia syndrome and to discuss the role of micromanipulation in the treatment of these patients.


METHODS
Case report.


METHODS
Private infertility clinic and assisted reproduction unit.


METHODS
Couple with male factor infertility due to Kartagener's/immotile cilia syndrome.


METHODS
The patient's partner underwent ICSI with testicular sperm.


METHODS
Semen characteristics, sperm viability, fertilization and cleavage rate, pregnancy, and birth after ICSI.


RESULTS
With testicular sperm, the two pronuclear fertilization rates were 53%. ICSI was successful in the first cycle. The uncomplicated pregnancy resulted in the birth of two healthy children, male/female twins.


CONCLUSIONS
With testicular sperm, successful oocyte fertilization after ICSI in couples with male Kartagener or immotile cilia syndrome is possible with nonprogressive motile sperm resulting in clinically healthy offsprings.
Kaushal
Manila
M
Department of Obstetrics & Gynecology, Disha Fertility & Surgical Center, Indore, India. dr_manila@yahoo.co.in <dr_manila@yahoo.co.in>
Baxi
Asha
A
D000328:Adult; D002925:Ciliary Motility Disorders / Q000473:pathology*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007619:Kartagener Syndrome / Q000473:pathology*; D008297:Male; D036801:Parturition; D011247:Pregnancy; D011272:Pregnancy, Multiple; D020554:Sperm Injections, Intracytoplasmic; D013094:Spermatozoa / Q000473:pathology*; D014427:Twins