Validity of the Dutch version of the Amyotrophic Lateral Sclerosis Assessment Questionnaire, ALSAQ-40, ALSAQ-5.
The objective was to validate the Dutch translation of the 40-item and 5-item Amyotrophic Lateral Sclerosis Assessment Questionnaire (ALSAQ-40, ALSAQ-5). Eighty-one ALS patients participated in this cross-sectional study. The measures used were the ALSAQ-40, the ALSAQ-5, MOS Short-Form-36 (SF-36) and Revised ALS Functional Rating Scale (ALSFRS-R). The Dutch ALSAQ-40 was sensitive to differences in disease severity (all scales Kruskal-Wallis, p<0.05), had no floor and few ceiling effects (Communication, Eating and Drinking scales), had excellent internal consistency reliability (all scales Cronbach's alpha >0.90, all item to subscale correlations above 0.40) and showed good construct validity as it correlated as expected with SF-36 and ALSFRS-R scores. The total and item scores of the ALSAQ-5 were strongly correlated with the corresponding total and subscale scores of the ALSAQ-40 (Spearman's rho >0.80). The ALSAQ-5 and ALSAQ-40 showed comparable correlations with the subscales of the SF-36 and the ALSFRS-R, except for Activities Daily Living and Independence (ADL). All other results of the Dutch ALSAQ-40 and ALSAQ-5 were comparable to those of the original UK questionnaires. It is concluded that the psychometric properties of the Dutch version of the ALSAQ-40 and the ALSAQ-5 are good and similar to those of the original English version.
Maessen
Maud
M
Department of Neurology UMC Utrecht, Netherlands. mmaessen@umcutrcht.nl
Post
Marcel W
MW
Maillé
Rianne
R
Lindeman
Eline
E
Mooij
Rob
R
Veldink
Jan H
JH
van den Berg
Leonard H
LH
D000203:Activities of Daily Living; D000465:Algorithms; D000690:Amyotrophic Lateral Sclerosis / Q000175:diagnosis* / Q000453:epidemiology*; D003627:Data Interpretation, Statistical; D019317:Evidence-Based Medicine / Q000379:methods; D005260:Female; D006305:Health Status Indicators; D006801:Humans; D016013:Likelihood Functions; D008297:Male; D008875:Middle Aged; D009426:Netherlands / Q000453:epidemiology; D011788:Quality of Life; D015203:Reproducibility of Results; D018401:Sample Size; D012680:Sensitivity and Specificity; D011795:Surveys and Questionnaires