title: Intracranial dissemination of primary spinal cord anaplastic oligodendroglioma.
abstract: We report the first case of a 22-year-old man, with a previously neurosurgically treated intramedullary anaplastic oligodendroglioma (World Health Organization grade III), who developed 19 months later two histologically proven intracranial metastases. We support a hypothesis whereby the anaplastic parts of tumors have spread along the spinal cord and brainstem via the cerebrospinal fluid pathways, a process that could be promoted by surgical manipulation, although the relative contribution of the two factors remains speculative.
authors: Neurosurgery Department, R. Salengro Hospital, Lille University Medical Center, Lille, France. caroleramirez@free.fr
authors: C
authors: C
authors: Ramirez
authors: O
authors: O
authors: Delrieu
authors: J-F
authors: JF
authors: Mineo
authors: G
authors: G
authors: Paradot
authors: M
authors: M
authors: Allaoui
authors: F
authors: F
authors: Dubois
authors: S
authors: S
authors: Blond
mesh_terms: D000328:Adult; D001932:Brain Neoplasms / Q000175:diagnosis / Q000556:secondary*; D002528:Cerebellar Neoplasms / Q000556:secondary; D017809:Fatal Outcome; D006801:Humans; D006849:Hydrocephalus / Q000209:etiology / Q000503:physiopathology / Q000628:therapy; D020547:Lateral Ventricles / Q000473:pathology / Q000503:physiopathology; D008297:Male; D009362:Neoplasm Metastasis / Q000473:pathology / Q000503:physiopathology*; D019635:Neurosurgical Procedures / Q000009:adverse effects; D009837:Oligodendroglioma / Q000175:diagnosis / Q000556:secondary*; D013120:Spinal Cord Neoplasms / Q000473:pathology* / Q000532:radiotherapy / Q000601:surgery; D013346:Subarachnoid Space / Q000473:pathology / Q000503:physiopathology*