Cervical radiculopathy secondary to Hodgkin's lymphoma.
BACKGROUND
Spinal cord/root compression is a rare complication of HL and usually seen in the setting of progressive, advanced disease. It is extremely rare to occur as an initial presentation of HL. We report a case of HL presented with bilateral cervical radiculopathy.


METHODS
A case report of a 42-year-old woman who presented with C8 cervical radiculopathy and paraspinal mass with extradural extension in C7-T1. Biopsy revealed HL. This case report represents a case of HL presenting with epidural disease, with nerve root compression as the only apparent site of clinical involvement. A review of the literature of patients with HL presenting with spinal cord/root compression is presented.


RESULTS
Our patient received chemotherapy and external beam radiation therapy. She achieved good recovery of her symptoms and complete response by radiologic criteria. Based on a review of the literature, Hodgkin's disease involving the spinal epidural space is very responsive to chemoradiotherapy with good prognosis for both functional recovery and complete response.


CONCLUSIONS
Chemoradiotherapy is a successful treatment for Hodgkin's disease presenting with spinal root compression. Surgery should be reserved for urgent decompression, if needed; palliation; and maintenance of function and stability.
Al-Khayat
Haitham
H
Department of Surgery, Saad Specialist Hospital, Al-Khobar 31952, Saudi Arabia. halkhayat@yahoo.com <halkhayat@yahoo.com>
Al-Khayat
Hisham
H
Al-Baker
Osama
O
Groof
Ala'
A
Sadeq
Adnan
A
Hayati
Hussein
H
Zarka
Zaki A
ZA
D000328:Adult; D002574:Cervical Vertebrae / Q000473:pathology; D004358:Drug Therapy; D004824:Epidural Space / Q000473:pathology / Q000503:physiopathology; D005260:Female; D006689:Hodgkin Disease / Q000150:complications* / Q000473:pathology* / Q000503:physiopathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D019547:Neck Pain / Q000209:etiology / Q000473:pathology / Q000503:physiopathology; D010292:Paresthesia / Q000209:etiology / Q000473:pathology / Q000503:physiopathology; D011843:Radiculopathy / Q000209:etiology* / Q000473:pathology* / Q000503:physiopathology; D011878:Radiotherapy; D013115:Spinal Canal / Q000473:pathology / Q000503:physiopathology; D013126:Spinal Nerve Roots / Q000473:pathology* / Q000503:physiopathology; D016896:Treatment Outcome