title: Nucleotide sequence diversity of the bexA gene in serotypeable Haemophilus influenzae strains recovered from invasive disease patients in Canada.
abstract: The bexA genes of 36 Haemophilus influenzae isolates were sequenced to reveal their nucleotide sequence diversity, which divided them into two groups, similar to clonal divisions I and II. This sequence diversity may lead to false-negative PCR results for H. influenzae infections if bexA is the chosen gene target.
authors: Vaccine Preventable Bacteria Diseases, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Manitoba, Canada R3E 32R2.
authors: Jianwei
authors: J
authors: Zhou
authors: Dennis K S
authors: DK
authors: Law
authors: Michelle L
authors: ML
authors: Sill
authors: Raymond S W
authors: RS
authors: Tsang
mesh_terms: D018528:ATP-Binding Cassette Transporters / Q000235:genetics*; D001426:Bacterial Proteins / Q000235:genetics*; D001483:Base Sequence; D002170:Canada; D005188:False Negative Reactions; D014644:Genetic Variation; D006192:Haemophilus Infections / Q000382:microbiology*; D006193:Haemophilus influenzae / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification; D006801:Humans; D008969:Molecular Sequence Data; D010802:Phylogeny; D016133:Polymerase Chain Reaction / Q000379:methods; D017422:Sequence Analysis, DNA; D012703:Serotyping
chemical_list: D018528:ATP-Binding Cassette Transporters; D001426:Bacterial Proteins; C068101:bexA protein, Haemophilus influenzae