title: An anterior or posterior approach to partial fundoplication? Long-term results of a randomized trial.
abstract: BACKGROUND
  Partial fundoplications have been popularized by their lower risk of mechanical side effects. The question then emerges whether a similar partial wrap should be done posterior or anterior to the distal esophagus? We therefore conducted a study to compare the long-term outcome of laparoscopic partial fundoplications constructed either as anterior (AF) or posterior (PF) repairs.
  
  
  METHODS
  Ninety-five patients were enrolled in a randomized clinical trial. After a mean follow up of 65 months, 43 AF and 45 PF patients remained in the study. The levels of reflux control and postfundoplication complaints were assessed by use of validated instruments.
  
  
  RESULTS
  A posterior fundoplication was found to provide significantly better control of reflux related symptoms (heartburn p < 0.0001, acid regurgitation p < 0.0001). This was also reflected in a significantly lower number of reoperations and need for antisecretory drug therapy. The earlier postoperative difference in postfundoplication symptoms had disappeared.
  
  
  CONCLUSIONS
  A laparoscopic posterior partial fundoplication offers a high and durable level of disease control with few side effects. The current anterior type of repair cannot be recommended due to insufficient reflux control.
authors: Department of Surgery, Sahlgrenska University Hospital Göteborg, Stockholm, Sweden. cecilia.engstrom@surgery.gu.se
authors: C
authors: C
authors: Engström
authors: H
authors: H
authors: Lönroth
authors: J
authors: J
authors: Mardani
authors: L
authors: L
authors: Lundell
mesh_terms: D000328:Adult; D050782:Esophageal pH Monitoring; D004945:Esophagoscopy; D005260:Female; D005500:Follow-Up Studies; D018662:Fundoplication / Q000379:methods*; D005745:Gastric Acidity Determination; D005764:Gastroesophageal Reflux / Q000175:diagnosis / Q000601:surgery*; D006801:Humans; D010535:Laparoscopy / Q000379:methods*; D008297:Male; D008365:Manometry; D008875:Middle Aged; D011183:Postoperative Complications / Q000175:diagnosis / Q000209:etiology*