title: Uptake of pneumococcal polysaccharide vaccine in at-risk populations in England and Wales 1999-2005.
abstract: The UK has had a pneumococcal polysaccharide vaccination (PPV) programme for groups at higher risk of invasive disease since 1992. This paper presents data from a sample of primary-care practices (Q-RESEARCH) of PPV uptake in patients according to their risk status. Of 2.9 million registered patients in 2005, 2.1% were vaccinated with PPV in the preceding 12 months and 6.5% in the preceding 5 years. Twenty-nine per cent of the registered population fell into one or more risk groups. The proportion of each risk group vaccinated in the previous 5 years ranged from 69% (cochlear implants), 53.4% (splenic dysfunction), 36.5% (chronic heart disease), 34.7% (diabetes), 22.9% (immunosuppressed), 28.7% (chronic renal disease), 15.9% (sickle cell disease) to 12.6% (chronic respiratory disease). Uptake was lower in areas where the non-white proportion of population was >10%. In conclusion, there remain large gaps in the uptake of PPV in several high-risk populations in the United Kingdom. Effective strategies need to be developed to address these deficiencies.
authors: HPA Centre for Infections, London, UK. Richard.Pebody@hpa.org.uk
authors: R G
authors: RG
authors: Pebody
authors: J
authors: J
authors: Hippisley-Cox
authors: S
authors: S
authors: Harcourt
authors: M
authors: M
authors: Pringle
authors: M
authors: M
authors: Painter
authors: G
authors: G
authors: Smith
mesh_terms: D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D002675:Child, Preschool; D004739:England / Q000453:epidemiology; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D011008:Pneumococcal Infections / Q000453:epidemiology* / Q000209:etiology / Q000517:prevention & control*; D022242:Pneumococcal Vaccines / Q000008:administration & dosage*; D015995:Prevalence; D018570:Risk Assessment; D013296:Streptococcus pneumoniae / Q000276:immunology*; D014611:Vaccination; D014852:Wales / Q000453:epidemiology
chemical_list: D022242:Pneumococcal Vaccines