title: [Observation on acupuncture at "Neitinggong" for antagonisting ototoxicity caused by gentamicin].
abstract: OBJECTIVE
  To explore the effect of acupuncture at "Neitinggong" drug-induced deafness.
  
  
  METHODS
  Guinea pig deafness model was prepared by injection of gentamicin (GM). Acupuncture was respectively given at the points "Neitinggong" "Tinggong" (SI 19) and non-acupoints on the auricle in the experimental animals in different groups and the effects of different points on the auditory brainstem response and cochlear hair cells were observed.
  
  
  RESULTS
  There was a significant difference between GM group and Neitinggong group, and between GM group and Tinggong group. There was no significant difference between GM group and the auricle group, and between Neitinggong group and Tinggong group.
  
  
  CONCLUSIONS
  Acupuncture at "Neitinggong" can strength the function of the internal ear, and relieve the injury of cochlear hair cells caused by gentamicin, which is an effective acupoint for treatment of drug-induced deafness.
authors: ENT Department of Second Hospital of Xian Jiaotong University, Shaanxi, China.
authors: Wei-jun
authors: WJ
authors: Ma
authors: Min
authors: M
authors: Xu
authors: Xiao-tong
authors: XT
authors: Zhang
authors: Hui
authors: H
authors: Liu
authors: Hong-yue
authors: HY
authors: Li
authors: Xiao-hong
authors: XH
authors: Zhou
mesh_terms: D015669:Acupuncture Points; D015670:Acupuncture Therapy; D000818:Animals; D000900:Anti-Bacterial Agents / Q000633:toxicity*; D003051:Cochlea / Q000187:drug effects / Q000473:pathology; D003638:Deafness / Q000139:chemically induced* / Q000517:prevention & control; D016057:Evoked Potentials, Auditory, Brain Stem / Q000187:drug effects; D005260:Female; D005839:Gentamicins / Q000633:toxicity*; D006168:Guinea Pigs; D006198:Hair Cells, Auditory / Q000187:drug effects / Q000473:pathology; D008297:Male
chemical_list: D000900:Anti-Bacterial Agents; D005839:Gentamicins