[Case report: diabetes flatbush - from ketoacidosis to non pharmacological treatment].
A subgroup of patients presents diabetic ketoacidosis at the onset of diabetes mellitus (DM) but later is classified as type 2 DM based on the clinical follow-up. These individuals, most commonly obese of African or Hispanic origin, have negative auto-antibodies associated with type 1 DM, but frequently HLA class II DRB1*03 and/or DRB1*04 are detected. This peculiar subtype of DM is commonly referred to as diabetes flatbush. Here we report the case of a Caucasian patient that exhibited the described evolution and in whom it was possible to withdraw insulin therapy. The possible factors associated with this favorable development are also discussed.
Rodacki
Melanie
M
Serviço de Nutrologia, Hospital Universitário Clementino Fraga Filho, Universidade Federal do Rio de Janeiro, RJ. mrodacki@hucff.ufrj.br
Zajdenverg
Lenita
L
Lima
Giovana Aparecida B
GA
Cavalcante Nunes
Reinaldo
R
Milech
Adolpho
A
de Oliveira
José Egídio Paulo
JE
D000328:Adult; D001323:Autoantibodies / Q000097:blood; D001786:Blood Glucose; D003920:Diabetes Mellitus / Q000175:diagnosis* / Q000178:diet therapy / Q000188:drug therapy; D003924:Diabetes Mellitus, Type 2 / Q000097:blood / Q000175:diagnosis / Q000178:diet therapy; D016883:Diabetic Ketoacidosis / Q000097:blood / Q000209:etiology*; D005260:Female; D006684:HLA-DR Antigens / Q000097:blood; D059811:HLA-DRB1 Chains; D006801:Humans; D007004:Hypoglycemic Agents / Q000008:administration & dosage; D007328:Insulin / Q000008:administration & dosage; D011247:Pregnancy; D011254:Pregnancy in Diabetics / Q000097:blood / Q000178:diet therapy; D044465:White People / Q000208:ethnology
D001323:Autoantibodies; D001786:Blood Glucose; D006684:HLA-DR Antigens; D059811:HLA-DRB1 Chains; D007004:Hypoglycemic Agents; D007328:Insulin