title: Relative contribution of body composition to bone mineral density at different sites in men and women of South Korea.
abstract: We examined the relative contribution of body composition to bone mineral density (BMD) at various sites in 1406 Korean rural men and women, aged 19-80 years, from July to August 2004. The BMD was measured at peripheral (distal forearm and calcaneus) and central (lumbar spine at L1-L4, femoral neck, trochanter, and Ward's triangle) using dual-energy X-ray absorptiometry. In multivariate analyses, the linear regression models were adjusted for relevant covariates. In premenopausal women, only lean mass had a significant positive correlation with BMD at all sites. In postmenopausal women, fat mass was significantly positively correlated with BMD at all sites, except the Ward's triangle; fat mass was the only determinant of BMD at the lumbar, distal forearm, and calcaneus sites, whereas both lean and fat mass contributed to BMD at the hip, with the effect of lean mass being slightly greater than that of fat mass. In younger men, lean mass had a significant positive contribution to BMD at all sites, whereas fat mass appeared to contribute negatively to BMD at all sites, except the calcaneus. In older men, lean mass made a significant positive contribution to the BMD at all sites; fat mass also made a significant positive contribution to the BMD at the forearm and calcaneus. These data indicate that in the Korean rural population, lean mass may be an important determinant of the BMD, whereas fat mass may contribute positively to BMD only in postmenopausal women and older men.
authors: Department of Preventive Medicine, Chonnam National University Medical School, 5, Hak 1-dong, Dong-gu, Gwangju 501-746, South Korea.
authors: Lian-Hua
authors: LH
authors: Cui
authors: Min-Ho
authors: MH
authors: Shin
authors: Sun-Seog
authors: SS
authors: Kweon
authors: Kyeong-Soo
authors: KS
authors: Park
authors: Young-Hoon
authors: YH
authors: Lee
authors: Eun-Kyung
authors: EK
authors: Chung
authors: Hae-Sung
authors: HS
authors: Nam
authors: Jin-Su
authors: JS
authors: Choi
mesh_terms: D000328:Adult; D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D001823:Body Composition / Q000502:physiology*; D015519:Bone Density / Q000502:physiology*; D001842:Bone and Bones / Q000502:physiology*; D005260:Female; D006801:Humans; D007723:Korea; D008297:Male; D008875:Middle Aged; D009928:Organ Specificity; D012044:Regression Analysis; D012727:Sex Characteristics