Detection and prediction of periodic patterns by the retina.
A fundamental task of the brain is detecting patterns in the environment that enable predictions about the future. Here, we show that the salamander and mouse retinas can recognize a wide class of periodic temporal patterns, such that a subset of ganglion cells fire strongly and specifically in response to a violation of the periodicity. This sophisticated retinal processing may provide a substrate for hierarchical pattern detection in subsequent circuits.
Schwartz
Greg
G
Department of Molecular Biology, Princeton University, Princeton, New Jersey 08544, USA.
Harris
Rob
R
Shrom
David
D
Berry
Michael J
MJ
D000200:Action Potentials / Q000502:physiology / Q000528:radiation effects; D000818:Animals; D004307:Dose-Response Relationship, Radiation; D066298:In Vitro Techniques; D007814:Larva; D051379:Mice; D008810:Mice, Inbred C57BL; D010507:Periodicity; D010775:Photic Stimulation / Q000379:methods; D012160:Retina / Q000166:cytology / Q000502:physiology*; D012165:Retinal Ganglion Cells / Q000502:physiology / Q000528:radiation effects; D013997:Time Factors; D014562:Caudata; D014794:Visual Fields / Q000502:physiology*; D014795:Visual Pathways / Q000502:physiology*