Segmental neurofibromatosis in association with a large congenital nevus and malignant melanoma.
We describe a patient with segmental neurofibromatosis and a large congenital nevus who developed malignant melanoma in the same anatomic distribution. The overlapping presentation suggests a common etiologic link between neurofibromatosis and large congenital nevi and the possibility that neurofibromatosis increases the risk of melanoma with large congenital nevi.
Doherty
Sean D
SD
Baylor College of Medicine, Houston, TX, USA.
George
Saira
S
Prieto
Victor G
VG
Gershenwald
Jeffrey E
JE
Duvic
Madeleine
M
D006801:Humans; D008297:Male; D008545:Melanoma / Q000150:complications / Q000473:pathology*; D008875:Middle Aged; D017253:Neurofibromatoses / Q000150:complications / Q000473:pathology*; D009506:Nevus / Q000150:complications / Q000473:pathology*; D012878:Skin Neoplasms / Q000150:complications / Q000473:pathology*