Viral load in blood is correlated with disease severity of neonatal coxsackievirus B3 infection: early diagnosis and predicting disease severity is possible in severe neonatal enterovirus infection.
We conducted a study during an outbreak of coxsackievirus B3 infection in 2005 and found that viral RNA could be detected in patients' blood specimens soon after the onset of fever, and the level of viral RNA was positively correlated with disease severity. Timely diagnosis is possible in severe neonatal enterovirus infection.
Yen
Meng-Hsiu
MH
Department of Pediatrics, Chang Gung Children's Hospital, Taoyuan, Taiwan.
Tsao
Kuo-Chien
KC
Huang
Yhu-Chering
YC
Huang
Chung-Guei
CG
Huang
Ya-Ling
YL
Lin
Reyin
R
Chang
Mei-Ling
ML
Huang
Chi-Chia
CC
Yan
Dah-Chin
DC
Lin
Tzou-Yien
TY
D003384:Coxsackievirus Infections / Q000097:blood / Q000453:epidemiology / Q000821:virology*; D004196:Disease Outbreaks; D029822:Enterovirus B, Human / Q000235:genetics / Q000254:growth & development*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D012367:RNA, Viral / Q000097:blood; D020133:Reverse Transcriptase Polymerase Chain Reaction / Q000379:methods; D012720:Severity of Illness Index; D013624:Taiwan / Q000453:epidemiology
D012367:RNA, Viral