Subclinical hyperthyroidism as a potential factor for dysfunctional uterine bleeding.
OBJECTIVE
To evaluate the functional status of the thyroid gland in apparently euthyroid women with dysfunctional uterine bleeding.


METHODS
Forty apparently euthyroid women with menorrhagia and no pathologic lesion in the genital tract were compared with 20 women having normal menstrual cycles as controls. All women underwent hormonal evaluation: serum total and free triiodothyronine (T3), thyroxine (T4), thyroid-stimulating hormone (TSH) and serum prolactin.


RESULTS
Statistically significant differences were observed in the values of TSH, total T3, free T3, free T4 and total T4 between the menorrhagia and the control group. Prolactin was increased significantly in the menorrhagia group.


CONCLUSIONS
Subclinical hyperthyroidism can be a potential risk factor for dysfunctional uterine bleeding. Other studies are needed to confirm our findings.
Attia
Abdel Hamid
AH
Department of Obstetrics and Gynecology, Department of Chemical Pathology, Cairo University, Cairo, Egypt.
Youssef
Dalia
D
Hassan
Neamat
N
El-Meligui
Mohamed
M
Kamal
Manal
M
Al-Inany
Hesham
H
D005260:Female; D006801:Humans; D006980:Hyperthyroidism / Q000150:complications*; D008183:Luteal Phase / Q000097:blood* / Q000502:physiology; D016555:Matched-Pair Analysis; D008595:Menorrhagia / Q000209:etiology*; D011388:Prolactin / Q000097:blood; D013972:Thyrotropin / Q000097:blood; D013974:Thyroxine / Q000097:blood; D014284:Triiodothyronine / Q000097:blood
D014284:Triiodothyronine; D011388:Prolactin; D013972:Thyrotropin; D013974:Thyroxine