title: Characteristics and impact of drug detailing for gabapentin.
abstract: BACKGROUND
  Sales visits by pharmaceutical representatives ("drug detailing") are common, but little is known about the content of these visits or about the impact of visit characteristics on prescribing behavior. In this study, we evaluated the content and impact of detail visits for gabapentin by analyzing market research forms completed by physicians after receiving a detail visit for this drug.
  
  
  RESULTS
  Market research forms that describe detail visits for gabapentin became available through litigation that alleged that gabapentin was promoted for "off-label" uses. Forms were available for 97 physicians reporting on 116 detail visits between 1995 and 1999. Three-quarters of recorded visits (91/116) occurred in 1996. Two-thirds of visits (72/107) were 5 minutes or less in duration, 65% (73/113) were rated of high informational value, and 39% (42/107) were accompanied by the delivery or promise of samples. During the period of this study, gabapentin was approved by the US Food and Drug Administration only for the adjunctive treatment of partial seizures, but in 38% of visits (44/115) the "main message" of the visit involved at least one off-label use. After receiving the detail visit, 46% (50/108) of physicians reported the intention to increase their prescribing or recommending of gabapentin in the future. In multivariable analysis, intent to increase future use or recommendation of gabapentin was associated with receiving the detail in a small group (versus one-on-one) setting and with low or absent baseline use of the drug, but not with other factors such as visit duration, discussion of "on-label" versus "off-label" content, and the perceived informational value of the presentation.
  
  
  CONCLUSIONS
  Detail visits for gabapentin were of high perceived informational value and often involved messages about unapproved uses. Despite their short duration, detail visits were frequently followed by physician intentions to increase their future recommending or prescribing of the drug.
authors: Affairs Medical Center, San Francisco, California, United States of America. mike.steinman@ucsf.edu
authors: Michael A
authors: MA
authors: Steinman
authors: G Michael
authors: GM
authors: Harper
authors: Mary-Margaret
authors: MM
authors: Chren
authors: C Seth
authors: CS
authors: Landefeld
authors: Lisa A
authors: LA
authors: Bero
mesh_terms: D000588:Amines / Q000191:economics; D003509:Cyclohexanecarboxylic Acids / Q000191:economics; D004345:Drug Industry / Q000191:economics / Q000379:methods*; D000077206:Gabapentin; D006801:Humans; D040541:Marketing / Q000191:economics / Q000379:methods*; D010820:Physicians / Q000191:economics; D005680:gamma-Aminobutyric Acid / Q000191:economics
chemical_list: D000588:Amines; D003509:Cyclohexanecarboxylic Acids; D005680:gamma-Aminobutyric Acid; D000077206:Gabapentin