[Botulinum toxin A injection for treatment-refractory giggle incontinence].
A 20-year-old woman reported about giggle incontinence despite antimuscarinic therapy. Therefore we injected botulinum toxin A into the detrusor muscle. The effect of botulinum toxin A appeared about 1 week after injection and no more leakage was observed even during vigorous laughter. A control uroflowmetry showed a good voiding rate without any residual volume. Botulinum toxin A might be an alternative for patients with giggle incontinence after unsuccessful antimuscarinic treatment.
Wefer
B
B
Klinik für Urologie und Kinderurologie, Universitätsklinikum Schleswig-Holstein, Campus Kiel, 24105, Kiel. bwefer@urology.uni-kiel.de
Seif
C
C
van der Horst
C
C
Jünemann
K P
KP
Braun
P M
PM
D000328:Adult; D019274:Botulinum Toxins, Type A / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D007273:Injections, Intramuscular; D007845:Laughter; D018727:Muscarinic Antagonists / Q000008:administration & dosage*; D017211:Treatment Failure; D016896:Treatment Outcome; D014549:Urinary Incontinence / Q000188:drug therapy*
D018727:Muscarinic Antagonists; D019274:Botulinum Toxins, Type A