Putting evidence into practice: evidence-based interventions to prevent, manage, and treat chemotherapy-induced nausea and vomiting.
Chemotherapy-induced nausea and vomiting (CINV) continues to have a considerable effect on the physical and psychological well-being of patients with cancer, despite significant advances in antiemetic drugs since the 1990s. This article reviews and summarizes past and current empirical evidence related to interventions for CINV. A resource that summarizes evidence-based interventions for CINV is critical for effective management of this distressing symptom. Pharmacologic and nonpharmacologic interventions are appraised. Finally, gaps in the literature and opportunities for research, education, and practice changes are discussed.
Tipton
Janelle M
JM
University of Toledo Medical Center, Ohio, USA. Janelle.Tipton@utoledo.edu
McDaniel
Roxanne W
RW
Barbour
Laurel
L
Johnston
Mary Pat
MP
Kayne
Marilyn
M
LeRoy
Patricia
P
Ripple
Marita L
ML
D000932:Antiemetics / Q000627:therapeutic use; D000970:Antineoplastic Agents / Q000009:adverse effects*; D019985:Benchmarking; D019317:Evidence-Based Medicine / Q000458:organization & administration*; D006301:Health Services Needs and Demand; D006801:Humans; D009325:Nausea / Q000139:chemically induced / Q000517:prevention & control; D024802:Nurse's Role; D015399:Nursing Research / Q000458:organization & administration*; D009859:Oncology Nursing / Q000458:organization & administration*; D017063:Outcome Assessment, Health Care; D010347:Patient Care Planning; D010353:Patient Education as Topic / Q000458:organization & administration; D017410:Practice Guidelines as Topic; D011322:Primary Prevention; D012064:Relaxation Therapy; D012702:Serotonin Antagonists; D014839:Vomiting / Q000139:chemically induced / Q000517:prevention & control
D000932:Antiemetics; D000970:Antineoplastic Agents; D012702:Serotonin Antagonists