title: Micronized, particulate dermal matrix to manage a non-healing pressure ulcer with undermined wound edges: a case report.
abstract: Pressure ulcers with undermined edges are generally hard to treat and may require surgical debridement and flap coverage. A woman with a 5-month history of a non-healing, undermined, sacro-coccygeal pressure ulcer presented for care at the author's wound care center. Because traditional wound care had failed and surgical debridement and repair was contraindicated due to her overall poor general health and malnutrition, an injectable dermal filler was applied inside the wound. The matrix filler was covered with secondary and tertiary dressings and the wound healed after 8 weeks with no adverse effects or infection. The results of this and previously published case studies suggest that injectable dermal matrix may be a viable option for non-surgical treatment of difficult-to-heal pressure ulcers with undermining. Additional safety, efficacy, and cost-effectiveness studies seem warranted.
authors: Morton Plant Hospital Wound Care Center, Clearwater, Fla., USA. rallam1@hotmail.com
authors: Reynald C
authors: RC
authors: Allam
mesh_terms: D001458:Bandages; D003094:Collagen / Q000737:chemistry / Q000494:pharmacology / Q000627:therapeutic use*; D003646:Debridement; D005260:Female; D006801:Humans; D007267:Injections; D008875:Middle Aged; D018579:Patient Selection; D003668:Pressure Ulcer / Q000473:pathology / Q000628:therapy*; D012447:Sacrum; D017592:Skin Care / Q000379:methods; D013524:Surgical Flaps; D016896:Treatment Outcome; D014945:Wound Healing / Q000187:drug effects
chemical_list: C471832:Cymetra; D003094:Collagen