[Myocardial infarction at the age under 50: influence of occupational xenobiotics (analysis of chemical elements in hair of patients)].
X-ray and fluorescence analysis covered elemental composition of hair in 39 patients with myocardial infarction and 23 healthy individuals. The highest "chemical pollution" was seen in myocardial infarction patients whose occupations are associated with xenobiotics exposure. Hair of those patients contain reliably high amounts of iron, copper, manganese, chromium, cadmium, lead, strontium, rubidium, potassium, bromium and clorine. Nearly two thirds of those patients had potassium and strontium levels considerably exceeding maximally allowable values. Reliably higher levels of some chemical elements in myocardial infarction patients vs. controls could be a proof of direct cause-effect relationships between xenobiotics influence and coronary affection in individuals aged under 50, especially subjected to regular risk factors.
Zerbino
D D
DD
Solomenchuk
T N
TN
D000328:Adult; D015415:Biomarkers / Q000032:analysis; D005260:Female; D006197:Hair / Q000737:chemistry*; D006219:Halogens / Q000032:analysis*; D006801:Humans; D008297:Male; D019216:Metals, Heavy / Q000032:analysis*; D008875:Middle Aged; D009203:Myocardial Infarction / Q000139:chemically induced / Q000378:metabolism*; D016273:Occupational Exposure / Q000009:adverse effects*; D011379:Prognosis; D012016:Reference Values; D012307:Risk Factors; D013050:Spectrometry, Fluorescence; D015262:Xenobiotics / Q000009:adverse effects*
D015415:Biomarkers; D006219:Halogens; D019216:Metals, Heavy; D015262:Xenobiotics