title: [Clinical, morphological, and microbiological characteristics of the Mallory-Weiss syndrome].
abstract: The profound clinico-morphological and immunological analysis was performed in patients suffering Mallory-Weiss syndrome (MWS). Doing endoscopic and morphological investigations the most dangerous foci of the affection were revealed and there links with the disease course severity and the recurrences rate established. The signs of unstable haemostasis were revealed according to the endoscopic investigation data. Morphological changes of gastric mucosa in patients suffering MWS are similar to those in duodenal ulcer disease. Polymorphism of mucosal microorganisms with E. coli, Streptococcus beta-haemoliticus, Klebsiella pneumoniae, Candida albicans predominance, which severe the disease course and cause the haemorrhage recurrence, was characteristic for MWS in 85% of observations. These causing agents are sensitive to II-III generation cephalosporins and fluoroquinolons in 75% of observations. The complex of conservative treatment must include, besides restorational, untiulcer, antihelicobacter and antibacterial therapy.
authors: V P
authors: VP
authors: Kryshen'
authors: M V
authors: MV
authors: Trofimov
authors: T V
authors: TV
authors: Novikova
authors: O I
authors: OI
authors: Novikov
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000627:therapeutic use; D000897:Anti-Ulcer Agents / Q000008:administration & dosage / Q000627:therapeutic use; D005260:Female; D005753:Gastric Mucosa / Q000187:drug effects / Q000276:immunology / Q000382:microbiology / Q000473:pathology; D006471:Gastrointestinal Hemorrhage / Q000209:etiology / Q000473:pathology / Q000517:prevention & control; D006801:Humans; D008297:Male; D008309:Mallory-Weiss Syndrome / Q000150:complications / Q000188:drug therapy / Q000276:immunology / Q000382:microbiology / Q000473:pathology; D008875:Middle Aged; D055502:Secondary Prevention
chemical_list: D000900:Anti-Bacterial Agents; D000897:Anti-Ulcer Agents