A prospective investigation of the prevalence and prognostic significance of weight loss and changes in body condition in feline cancer patients.
The objectives of this study were to prospectively identify and characterize weight loss and changes in body condition in feline cancer patients and to investigate the prognostic significance of these findings. Fifty-seven cats with neoplasia were evaluated. Body condition was assessed with a nine-point scoring system (BCS) and multiple sites were assessed for muscle and fat mass using four-point scoring systems. Feline cancer patients had a mean BCS of 4.4+/-2.1 kg (1=cachectic, 5=optimal, 9=obese). Fat mass was reduced in both sites assessed in 60% of the patients. Muscle mass was reduced at all three sites assessed in 91% of the patients. Feline cancer patients having a BCS <5 had a median survival time (MST) of 3.3 months compared to that of 16.7 months for cats with a BCS of > or = 5 (P=0.008).
Baez
Jennifer L
JL
Department of Clinical Studies-Philadelphia, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104-6010, USA.
Michel
Kathryn E
KE
Sorenmo
Karin
K
Shofer
Frances S
FS
D000818:Animals; D002100:Cachexia / Q000209:etiology / Q000473:pathology / Q000662:veterinary*; D002371:Cat Diseases / Q000175:diagnosis* / Q000453:epidemiology* / Q000209:etiology / Q000401:mortality; D002415:Cats; D005260:Female; D008297:Male; D009369:Neoplasms / Q000150:complications / Q000175:diagnosis / Q000453:epidemiology / Q000662:veterinary*; D010414:Pennsylvania / Q000453:epidemiology; D011237:Predictive Value of Tests; D015995:Prevalence; D011446:Prospective Studies; D012720:Severity of Illness Index; D016019:Survival Analysis