title: ESR imaging investigations of two-phase systems.
abstract: The possibilities of electron spin resonance (ESR) and electron spin resonance imaging (ESRI) for investigating the properties of the spin probes TEMPO and TEMPOL in two-phase systems have been examined in the systems water/n-octanol, Miglyol/Miglyol, and Precirol/Miglyol. Phases and regions of the phase boundary could be mapped successfully by means of the isotropic hyperfine coupling constants, and, moreover, the quantification of rotational and lateral diffusion of the spin probes was possible. For the quantitative treatment of the micropolarity, a simplified empirical model was established on the basis of the Nernst distribution and the experimentally determined isotropic hyperfine coupling constants. The model does not only describe the summarized micropolarities of coexisting phases, but also the region of the phase boundary, where solvent molecules of different polarities and tendencies to form hydrogen bonds compete to interact with the NO group of the spin probe.
authors: Department of Pharmacy, Free University of Berlin, Kelchstrasse 31, D-12169 Berlin, Germany. wfh@zedat.fu-berlin.de
authors: Werner
authors: W
authors: Herrmann
authors: Reinhard
authors: R
authors: Stösser
authors: Hans-Hubert
authors: HH
authors: Borchert
mesh_terms: D003497:Cyclic N-Oxides / Q000737:chemistry; D004578:Electron Spin Resonance Spectroscopy / Q000379:methods*; D006860:Hydrogen Bonding; D008956:Models, Chemical; D044367:Phase Transition; D012997:Solvents / Q000737:chemistry; D013113:Spin Labels
chemical_list: D003497:Cyclic N-Oxides; D012997:Solvents; D013113:Spin Labels; C001803:tempol; C003959:TEMPO