title: Fatal and widespread skeletal myopathy confirmed morphologically years after initiation of simvastatin therapy.
abstract: A patient is described in whom fatal myopathy occurred, and its cause appears to be the consequence of simvastatin therapy.
authors: Department of Internal Medicine, Baylor University Medical Center, Dallas, Texas 75205, USA.
authors: David Demitry
authors: DD
authors: Boltan
authors: Whitney
authors: W
authors: Lachar
authors: Anita
authors: A
authors: Khetan
authors: John-Paul
authors: JP
authors: Bouffard
authors: William Clifford
authors: WC
authors: Roberts
mesh_terms: D002114:Calcinosis / Q000473:pathology; D003680:Deglutition Disorders / Q000139:chemically induced; D004401:Dysarthria / Q000139:chemically induced; D004417:Dyspnea / Q000139:chemically induced; D017809:Fatal Outcome; D005355:Fibrosis; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000009:adverse effects*; D000960:Hypolipidemic Agents / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D018485:Muscle Fibers, Skeletal / Q000473:pathology; D018908:Muscle Weakness / Q000139:chemically induced; D009135:Muscular Diseases / Q000139:chemically induced* / Q000473:pathology; D009336:Necrosis; D019821:Simvastatin / Q000009:adverse effects*
chemical_list: D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D000960:Hypolipidemic Agents; D019821:Simvastatin