title: Cystic echinococcosis in Central Saudi Arabia: a 5-year experience.
abstract: OBJECTIVE
  In this series of patients we aim to describe aspects of presentation, diagnosis and management of patients suffering from Echinococcosis in an endemic region.
  
  
  METHODS
  This is an observational study done at Riyadh Medical Complex, Saudi Arabia from 1999 to 2004. All adult patients admitted with the primary or incidental diagnosis of echinococcosis were included. These patients were followed up for 6 months. Data relating to patients' demographic characteristics, mode and duration of presentation, investigations, complications and treatment offered was collected. This data was then analyzed using SPSS 11.0.
  
  
  RESULTS
  117 patients with a mean age of 40.9+/-20.7 years were admitted, male to female ratio being 1.7:1. 114 (97.4%) originated from Middle East which is an endemic area. Pain right upper quadrant (RUQ), followed by cough were the commonest symptoms. Nine patients presented with jaundice +/- choleangitis: 3 patients had intrabiliary rupture of the hydatid cyst, while 6 had extrinsic compression. Six patients had infected cyst. Fourteen patients had intrabronchial rupture diagnosed on bronchoscopy. Twenty five (21.4%) patients presented with recurrent disease. The Haemagglutination Inhibition test gave a sensitivity of 78.6. All cysts were visualized using USG, CXR and CT scan. Endocystectomy was the most frequent procedure. Post op 8 patients had biliary leakage and 3 had bronchopleural fistula a majority of whom settled conservatively while two required ERCP and one patient with bronchopleural fistula required surgery. Fifteen patients had infection related complications. During our follow up period no recurrences were recorded. All patients undergoing surgery also received medical treatment. Twenty five patients (21.4%) were unable to undergo operative treatment due to multiple reasons. They were medically treated.
  
  
  CONCLUSIONS
  Cystic Echinococcosis is a disease of the middle aged. Ultrasonogram combined with a serological assay is the best diagnostic tool available for abdominal echinococcosis allowing diagnosis and staging, while chest X ray is the best screen for the pulmonary disease. The recommended treatment is endocystectomy with antihelmenthic therapy. But the problem of early detection of echinococcosis in endemic areas needs attention by workers as this approach can potentially prevent the devastating complications due to this disease.
authors: Department of Surgery, King Saud University, College of Medicine, University Unit, RMC, Riyadh, Kingdom of Saudi Arabia.
authors: Fraz
authors: F
authors: Fahim
authors: Saleh Mohammad
authors: SM
authors: Al Salamah
mesh_terms: D015746:Abdominal Pain / Q000209:etiology; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015766:Albendazole / Q000627:therapeutic use; D000981:Antiprotozoal Agents / Q000627:therapeutic use; D003371:Cough / Q000209:etiology; D004443:Echinococcosis / Q000453:epidemiology* / Q000628:therapy; D019353:Endemic Diseases; D004802:Eosinophilia / Q000453:epidemiology; D005260:Female; D005334:Fever / Q000209:etiology; D006385:Hemagglutination Inhibition Tests; D006801:Humans; D007565:Jaundice / Q000209:etiology; D007964:Leukocytosis / Q000209:etiology; D008297:Male; D008463:Mebendazole / Q000627:therapeutic use; D008875:Middle Aged; D012421:Rupture; D012529:Saudi Arabia / Q000453:epidemiology; D055815:Young Adult
chemical_list: D000981:Antiprotozoal Agents; D008463:Mebendazole; D015766:Albendazole