A case of hypertrophic pachymeningitis with prolonged headache, attributable to Epstein-Barr virus.
Hypertrophic pachymeningitis is a condition characterized by significant chronic inflammatory thickening of the cranial dura mater, frequently presenting with symptoms such as headache and cranial neuropathy. In this report, we describe a very rare case of hypertrophic pachymeningitis, considered to be attributable to Epstein-Barr virus (EBV), which was diagnosed in a patient who visited our hospital with a complaint of ongoing severe headaches. The diagnosis was based on positive specific serum EBV antibody titers, with VCA-IgM levels of less than 1:10, VCA-IgG levels of 1:160, and EBNA levels of 1:40, as well as on the results of magnetic resonance imaging of the head with contrast media.
Okuma
Hirohisa
H
Department of Neurology, Tokai University Tokyo Hospital, Tokyo, Japan.
Kobori
Satoko
S
Shinohara
Yukito
Y
Takagi
Shigeharu
S
D000328:Adult; D004388:Dura Mater / Q000473:pathology*; D006261:Headache / Q000150:complications / Q000473:pathology / Q000821:virology*; D004854:Herpesvirus 4, Human / Q000302:isolation & purification*; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D008581:Meningitis / Q000150:complications / Q000473:pathology / Q000821:virology*