title: A novel cytotoxic lignan from Seseli annuum L.
abstract: A new tetrahydrofuranoid lignan named seselinone was isolated from the aerial parts of Seseli annuum, together with three known lignans (eudesmin, magnone A and hernone) and prenylated coumarin umbelliprenin. Seselinone and eudesmin showed cytotoxic activity against C6 rat glioma cell cultures.
authors: Institute for Chemistry, Technology and Metallurgy, Njegoseva 12, 11000 Belgrade, Serbia.
authors: Ivan
authors: I
authors: Vucković
authors: Vladimir
authors: V
authors: Trajković
authors: Slobodan
authors: S
authors: Macura
authors: Vele
authors: V
authors: Tesević
authors: Peda
authors: P
authors: Janaćković
authors: Slobodan
authors: S
authors: Milosavljević
mesh_terms: D000818:Animals; D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry* / Q000633:toxicity*; D019661:Apiaceae / Q000737:chemistry*; D045744:Cell Line, Tumor; D005910:Glioma / Q000473:pathology*; D017705:Lignans / Q000737:chemistry / Q000633:toxicity*; D035261:Plant Components, Aerial / Q000737:chemistry; D051381:Rats
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D017705:Lignans; C523277:seselinone