Interoceptive basis to craving.
Awareness of one's physiology is an important component of emotion. How might these processes be related to addiction? In a recent issue of Science, Naqvi et al. demonstrated that smoking addiction is disrupted by damage to the insula cortex. This suggests that brain circuits mediating interoception also contribute to craving states.
Gray
Marcus A
MA
Brighton and Sussex Medical School, University of Sussex Falmer Campus, Brighton BN1 6PX, United Kingdom. m.a.gray@bsms.ac.uk
Critchley
Hugo D
HD
D001921:Brain / Q000503:physiopathology*; D002540:Cerebral Cortex / Q000503:physiopathology; D006801:Humans; D009042:Motivation; D009434:Neural Pathways; D012907:Smoking / Q000503:physiopathology; D016540:Smoking Cessation; D019966:Substance-Related Disorders / Q000503:physiopathology* / Q000523:psychology*