Current applications of the intraoperative parathyroid hormone assay in parathyroid surgery.
Parathyroid hormone measurement using a two-site immunochemiluminometric assay has allowed for a rapid and accurate technique that has found its way into the operative armamentarium of some parathyroid surgeons. It can be used to assess the completeness of parathyroid gland resection and allow for a minimally invasive parathyroidectomy. This operative approach has become a popular marketing tool, providing patients with confidence in their surgical outcome. The purpose of this review is to provide the surgeon with the practical points and pitfalls of the use of intraoperative parathyroid hormone in the treatment of parathyroid disease.
Richards
Melanie L
ML
Mayo Clinic, Department of Surgery, 200 First Street SW, Rochester, MN 55905, USA.
Grant
Clive S
CS
D000236:Adenoma / Q000097:blood / Q000601:surgery; D006801:Humans; D006961:Hyperparathyroidism / Q000097:blood / Q000235:genetics / Q000601:surgery; D006962:Hyperparathyroidism, Secondary / Q000097:blood / Q000601:surgery; D008163:Luminescent Measurements / Q000379:methods*; D019060:Minimally Invasive Surgical Procedures; D016343:Monitoring, Intraoperative / Q000379:methods*; D009377:Multiple Endocrine Neoplasia / Q000097:blood / Q000601:surgery; D010281:Parathyroid Hormone / Q000097:blood*; D010282:Parathyroid Neoplasms / Q000097:blood / Q000601:surgery; D016105:Parathyroidectomy / Q000379:methods; D012086:Reoperation
D010281:Parathyroid Hormone