title: [Hepatitis E virus infection in population of non-remunerate blood donors in Shaoxing].
abstract: OBJECTIVE
  To investigate the incidence of HEV infection in population of non-remunerate blood donors in Shaoxing.
  
  
  METHODS
  Blood specimens from 3701 non-remunerate blood donors were collected, ELISA were used to study anti-HEV IgG and IgM antibodies, RT-PCR were further used to study HEV RNA in samples from donors whose anti-HEV IgM was positive.
  
  
  RESULTS
  Anti-HEV IgG positive rate was 29.19% (1107/3701), anti-HEV IgM positive rate was 1.35% (50/3701) among non-remunerate blood donors in Shaoxin. Six cases were positive for HEV RNA. The positive rate was 0.16% (6/3701), and all the 6 cases belonged to HEV genotype 1. Different seasons showed no interference on the positive rate of IgG and IgM.
  
  
  CONCLUSIONS
  The detecting and studying of HEV infection among donors was important to ensure the safety of blood products and blood transfusion.
authors: Shaoxing Blood Center, Shaoxing 312041, China.
authors: Lie-yong
authors: LY
authors: Sang
authors: Pei-fen
authors: PF
authors: Zhuang
authors: Li-qiang
authors: LQ
authors: Fu
authors: Yi
authors: Y
authors: Liu
authors: Sheng-xiang
authors: SX
authors: Ge
authors: Jun
authors: J
authors: Zhang
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D001782:Blood Donors; D002681:China / Q000453:epidemiology; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D016751:Hepatitis E / Q000097:blood* / Q000453:epidemiology / Q000821:virology; D016752:Hepatitis E virus / Q000145:classification / Q000235:genetics* / Q000276:immunology; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D007075:Immunoglobulin M / Q000097:blood; D008297:Male; D008875:Middle Aged; D010802:Phylogeny; D012367:RNA, Viral / Q000097:blood / Q000235:genetics; D020133:Reverse Transcriptase Polymerase Chain Reaction; D055815:Young Adult
chemical_list: D007074:Immunoglobulin G; D007075:Immunoglobulin M; D012367:RNA, Viral