Tritium labelling of several potent fluorinated antipsychotic drugs at high specific activity.
Methods are presented to synthesize and characterize [methylene-3H] haloperidol 2 and [N-methyl-3H]trifluoperazine 6.
Ahern
David G
DG
PerkinElmer Life and Analytical Sciences, Inc., 549 Albany St., Boston, MA 02118, USA.
Laseter
Anne G
AG
Filer
Crist N
CN
D014150:Antipsychotic Agents / Q000138:chemical synthesis*; D006220:Haloperidol / Q000031:analogs & derivatives / Q000138:chemical synthesis*; D009682:Magnetic Resonance Spectroscopy; D014268:Trifluoperazine / Q000138:chemical synthesis*; D014316:Tritium / Q000737:chemistry*
D014150:Antipsychotic Agents; D014316:Tritium; D014268:Trifluoperazine; D006220:Haloperidol