title: Treatment outcome cohort analysis in an integrated DOTS and DOTS-Plus TB program in Latvia.
abstract: International guidelines for treatment outcome analysis of tuberculosis cases have been published and are widely used. They do not, however, fully address the incorporation of multidrug-resistant tuberculosis (MDR-TB) cases. Here we present an approach to cohort analysis of treatment outcomes for all registered TB cases, including MDR-TB cases. We analyzed all new pulmonary smear- and/or culture-positive cases registered in Latvia during 2002. Analysis of treatment outcomes at 24 months after initial case registration showed overall treatment success at 84%. This approach to outcome analysis is possible only for settings where MDR-TB treatment is established.
authors: State Agency for Tuberculosis and Lung Diseases, Riga, Latvia. vija@tuberculosis.lv
authors: V
authors: V
authors: Riekstina
authors: V
authors: V
authors: Leimane
authors: T H
authors: TH
authors: Holtz
authors: J
authors: J
authors: Leimans
authors: C D
authors: CD
authors: Wells
mesh_terms: D000995:Antitubercular Agents / Q000008:administration & dosage*; D015331:Cohort Studies; D023801:Directly Observed Therapy / Q000379:methods*; D006801:Humans; D007844:Latvia; D015397:Program Evaluation; D016896:Treatment Outcome; D014376:Tuberculosis / Q000188:drug therapy* / Q000401:mortality; D018088:Tuberculosis, Multidrug-Resistant / Q000188:drug therapy* / Q000401:mortality
chemical_list: D000995:Antitubercular Agents