title: piRNAs in the germ line.
abstract: Small noncoding RNAs have emerged as potent regulators of gene expression at both transcriptional and posttranscriptional levels. Recently, a class of small RNAs that interact with Piwi proteins has been discovered in the mammalian germ line and Drosophila. These Piwi-interacting RNAs (piRNAs) represent a distinct small RNA pathway.
authors: Yale Stem Cell Center, Yale University School of Medicine, New Haven, CT 06510, USA. haifan.lin@yale.edu
authors: Haifan
authors: H
authors: Lin
mesh_terms: D000818:Animals; D060565:Argonaute Proteins; D004330:Drosophila; D029721:Drosophila Proteins / Q000378:metabolism; D044127:Epigenesis, Genetic; D018507:Gene Expression Regulation, Developmental; D005854:Germ Cells / Q000166:cytology / Q000378:metabolism*; D051379:Mice; D010448:Peptide Initiation Factors / Q000378:metabolism; D014176:Protein Biosynthesis; D011506:Proteins / Q000378:metabolism*; D020871:RNA Stability; D022661:RNA, Untranslated / Q000235:genetics / Q000378:metabolism*; D034743:RNA-Induced Silencing Complex
chemical_list: C518392:AGO3 protein, Drosophila; D060565:Argonaute Proteins; D029721:Drosophila Proteins; D010448:Peptide Initiation Factors; C448522:Piwil1 protein, mouse; D011506:Proteins; D022661:RNA, Untranslated; D034743:RNA-Induced Silencing Complex; C436124:aub protein, Drosophila; C116498:piwi protein, Drosophila