Vascular reconstruction with the superficial femoral vein following major oncologic resection.
BACKGROUND
Involvement of critical vascular structures has historically been considered a contraindication to tumor resection. This study describes outcomes following radical oncologic resection with concomitant resection of critical vascular structures and reconstruction with the superficial femoral vein (SFV).


METHODS
All patients undergoing radical oncologic resection requiring resection of major vascular structures and concomitant reconstruction using the SFV as conduit were retrospectively reviewed. Primary outcomes were surgical morbidity and mortality; secondary measures included long-term patency and oncologic outcomes.


RESULTS
Seven patients were included. There were three retroperitoneal and two groin sarcomas, and two squamous cell carcinomas metastatic to groin lymph nodes. No perioperative mortality occurred. Five patients experienced minor morbidity. One vein graft in a patient with pre-existing chronic deep venous thrombosis (DVT) occluded post-operatively. No subsequent long-term venous or arterial graft occlusions occurred (median 20.2 months, range 9.0-49.7). Two patients died of tumor recurrence during follow-up.


CONCLUSIONS
Resection of tumors involving critical vascular structures is feasible. The SFV conduit is a versatile option for major vascular reconstruction, providing good long-term patency rates with acceptable morbidity and mortality. Vascular resection and reconstruction with the SFV offers another technique to provide limb-sparing surgery in patients traditionally offered only amputation, while providing favorable oncologic outcomes.
McKay
Andrew
A
Department of Surgery, Division of Surgical Oncology, University of Calgary, Calgary, Alberta, Canada. andrewmc@cancerboard.ab.ca
Motamedi
Mona
M
Temple
Walley
W
Mack
Lloyd
L
Moore
Randy
R
D001807:Blood Vessel Prosthesis; D019917:Blood Vessel Prosthesis Implantation; D002294:Carcinoma, Squamous Cell / Q000098:blood supply / Q000401:mortality / Q000601:surgery; D018572:Disease-Free Survival; D005268:Femoral Vein / Q000601:surgery*; D006801:Humans; D023821:Limb Salvage; D018714:Radiotherapy, Adjuvant; D012186:Retroperitoneal Neoplasms / Q000098:blood supply / Q000401:mortality / Q000601:surgery*; D012189:Retrospective Studies; D012501:Saphenous Vein; D012509:Sarcoma / Q000098:blood supply / Q000401:mortality / Q000601:surgery*; D012983:Soft Tissue Neoplasms / Q000098:blood supply / Q000401:mortality / Q000601:surgery*; D016896:Treatment Outcome; D014654:Vascular Patency; D014656:Vascular Surgical Procedures / Q000379:methods*; D020246:Venous Thrombosis / Q000150:complications / Q000378:metabolism