Apolipoprotein E gene epsilon2/epsilon3/epsilon4 polymorphism and myocardial infarction: case-control study in a large population sample.
It has not been clearly established yet whether the epsilon2/epsilon3/epsilon4 polymorphism of the gene encoding apolipoprotein E is associated with myocardial infarction. We addressed this issue in a large case-control sample and found no statistically significant relationship between the epsilon2/epsilon3/epsilon4 polymorphism and myocardial infarction. The epsilon2 allele and epsilon2epsilon3 genotype showed trends towards lower risks of myocardial infarction than the epsilon3epsilon3 genotype.
Koch
Werner
W
Hoppmann
Petra
P
Schömig
Albert
A
Kastrati
Adnan
A
D053329:Apolipoprotein E2 / Q000235:genetics; D053318:Apolipoprotein E3 / Q000235:genetics; D053327:Apolipoprotein E4 / Q000235:genetics; D001057:Apolipoproteins E / Q000235:genetics*; D016022:Case-Control Studies; D005838:Genotype; D006801:Humans; D009203:Myocardial Infarction / Q000235:genetics*; D011110:Polymorphism, Genetic; D012307:Risk Factors
D053329:Apolipoprotein E2; D053318:Apolipoprotein E3; D053327:Apolipoprotein E4; D001057:Apolipoproteins E