Risk assessment in haematopoietic stem cell transplantation: viral status.
Viral infections have been important complications in the transplant procedure from the early days of stem-cell transplantation, causing significant morbidity and mortality. It is important for the management of patients to assess the risk for viral infections that might develop after the stem-cell transplantation. This can be exemplified by cytomegalovirus (CMV) and other herpesviruses, but risk assessment is also important for other viral infections. The aim of this review is to describe current knowledge regarding recipient and donor serological status for viral infections.
Ljungman
Per
P
Hematology Center, Karolinska University Hospital, Karolinska Institute, SE-14186 Stockholm, Sweden. per.ljungman@ki.se
D000163:Acquired Immunodeficiency Syndrome / Q000276:immunology; D000818:Animals; D000914:Antibodies, Viral / Q000032:analysis; D003586:Cytomegalovirus Infections / Q000209:etiology / Q000276:immunology; D017977:Deltaretrovirus / Q000276:immunology; D006086:Graft vs Host Disease / Q000276:immunology / Q000517:prevention & control / Q000821:virology; D018380:Hematopoietic Stem Cell Transplantation / Q000009:adverse effects; D006561:Herpes Simplex / Q000276:immunology; D014645:Herpesvirus 3, Human / Q000276:immunology; D004854:Herpesvirus 4, Human / Q000276:immunology; D006801:Humans; D012136:Respiratory Syncytial Viruses / Q000276:immunology; D018570:Risk Assessment; D014019:Tissue Donors; D014777:Virus Diseases / Q000209:etiology / Q000276:immunology*; D014902:West Nile virus / Q000276:immunology
D000914:Antibodies, Viral