[Multipotential differentiation and potential applications of adipose-derived stem cells].
Adipose tissue contains a population of multipotent cells called adipose-derived stem cells (ADSCs). With the similar properties of marrow-derived mesenchymal stem cells, ADSCs have the ability to differentiate differentiate towards adipogenic, osteogenic, chondrogenic, myogenic, endothelial, hematopoietic, hepatic, islet, and neurogenic cell lineages. As adipose tissue in harvested in large amounts with minimal morbidity, it can be widely used in tissue engineering, organ repair and gene therapy. This paper focused on the plasticity of ADSCs and reviewed the new advances of this field. Finally, the problems and prospect for application was also discussed.
Han
Zheng-Bin
ZB
Institute of Biotechnology, Academy of Military Medical Sciences, Beijing 100071, China. hanzhengbin@yahoo.com.cn
Chen
Hong-Xing
HX
Deng
Ji-Xian
JX
D000273:Adipose Tissue / Q000166:cytology* / Q000378:metabolism; D000818:Animals; D015703:Antigens, CD / Q000378:metabolism; D018929:Cell Culture Techniques; D002454:Cell Differentiation; D015316:Genetic Therapy; D006801:Humans; D039902:Multipotent Stem Cells / Q000166:cytology* / Q000378:metabolism; D013234:Stem Cells / Q000166:cytology* / Q000378:metabolism; D023822:Tissue Engineering
D015703:Antigens, CD