An adrenal gland nodule presenting as an early sign of metastatic spread from colorectal cancer: report of two cases.
The presence of an adrenal gland nodule may be an early or late sign of metastatic spread from colorectal cancer. It usually appears when the internal malignancy is widely disseminated and has been previously diagnosed. Adrenal insufficiency can be compatible with bilateral and diffuse involvement of this uncommon site of disease. Although a surgical approach can be proposed in some circumstances, chemotherapy is usually the only therapeutic option. We present 2 cases that document examples of both events, so as to illustrate the most relevant aspects of this condition.
Rosati
Gerardo
G
Medical Oncology Unit, S. Carlo Hospital, Potenza, Italy. rosatiger@yahoo.com
Tramutola
Giuseppe
G
D'Alessandro
Nicola
N
Chiacchio
Rosistella
R
Vita
Giulia
G
Scutari
Franco
F
Manzione
Luigi
L
D000230:Adenocarcinoma / Q000150:complications / Q000556:secondary*; D000310:Adrenal Gland Neoplasms / Q000150:complications / Q000556:secondary*; D000368:Aged; D015179:Colorectal Neoplasms / Q000150:complications / Q000473:pathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009392:Nephrectomy; D053040:Nephrolithiasis / Q000150:complications / Q000601:surgery; D049268:Positron-Emission Tomography; D014057:Tomography, X-Ray Computed