[Tuberculosis after organ transplantation: clinical analysis and literature review].
OBJECTIVE
To describe the clinical features, diagnosis and treatment of tuberculosis after organ transplantation.


METHODS
The clinical data of 25 cases of tuberculosis after organ transplantation were retrospectively analyzed.


RESULTS
Sixty-eight percent of the patients presented only mild symptoms. Fever, cough, malaise and chest tightness were among the most common manifestations. Pulmonary tuberculosis, pleurisy, miliary lesions, lymph node disease, and kidney tuberculosis were common. Involvement of two organs were present in 72% (18/25) of the patients. Radiology showed soft lesions, miliary nodules, pleural effusion, hilar and mediastinal lymphadenopathy. Bacteriology and histology were used to confirm the diagnosis in most cases. The average time from presentation to diagnosis was 38 d. The effective rate of therapy was 76% (19/25).


CONCLUSIONS
More attention should be paid to tuberculosis after organ transplantation and immunosuppression. Prompt diagnosis and treatment are important measures to reduce the mortality.
Wang
Wei
W
Research Institute of Tuberculosis of Secondary Affiliated Hospital, PLA General Hospital, Beijing 100091, China.
Wang
An-sheng
AS
Wang
Zhong-yuan
ZY
Wang
Jin-he
JH
Lin
Ming-gui
MG
Zhang
Tao
T
Li
Jing
J
An
Hui-ru
HR
Li
Yan-feng
YF
D000328:Adult; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects; D008297:Male; D008875:Middle Aged; D016377:Organ Transplantation; D012189:Retrospective Studies; D014376:Tuberculosis / Q000209:etiology*
D007166:Immunosuppressive Agents