[Studies on chemical constituents from the fruiting bodies of Ganoderma sinense Zhao, Xu et Zhang].
OBJECTIVE
To study the chemical constituents from the fruiting bodies of Ganoderma sinense Zhao, Xu et Zhang.


METHODS
To isolated the compounds by silica gel and sephadex LH -20 column chromatography and their structures were elucidate by means of spectral analysis.


RESULTS
Six sterols, one fatty acid and one of diketopiperazines were obtained from CHCl3 fraction of EtOH extract and identified as ergosta-7, 22-dien-3beta-ol (1), ergosterol (2), 6, 9-epidioxyergosta-7, 22-dien-3beta-ol (3), 5, 8-epidioxiergosta-6, 22-dien-3beta-ol (4), ergosta-7, 22-dien-3-one (5), beta-sitosterol (6), alpha-Hydroxytetracosanoic acid (7), cyclo (D-Pro-D-Val) (8).


CONCLUSIONS
Componds 1-8 are isolated from G. sinense Zhao, Xu et Zhang for the first time.
Liu
Chao
C
Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Beijing 100050, China.
Wang
Hong-qing
HQ
Li
Bao-ming
BM
Chen
Ruo-yun
RY
D002850:Chromatography, Gel / Q000379:methods; D004875:Ergosterol / Q000031:analogs & derivatives* / Q000737:chemistry / Q000302:isolation & purification*; D048690:Fruiting Bodies, Fungal / Q000737:chemistry*; D032902:Ganoderma / Q000737:chemistry*; D012855:Sitosterols / Q000737:chemistry / Q000302:isolation & purification; D013057:Spectrum Analysis / Q000379:methods
D012855:Sitosterols; C417570:ergosta-7,22-dien-3-one; C025473:gamma-sitosterol; D004875:Ergosterol