Pulmonary and cutaneous nocardiosis in a patient treated with corticosteroids.
Nocardiosis is a localized or disseminated infection caused by gram-positive bacteria of the genus Nocardia. The infection most commonly affects the lungs, skin and central nervous system. Nocardiosis principally occurs in individuals with cellular immunodeficiency and should be considered in the differential diagnosis when such individuals present respiratory, cutaneous or neurological alterations. Herein, we report a case of pulmonary and cutaneous nocardiosis in a patient receiving oral corticosteroids to treat bronchiolitis obliterans accompanied by organizing pneumonia of unknown origin. After long-term treatment with sulfamethoxazole-trimethoprim, the clinical and radiological profile improved.
Baldi
Bruno Guedes
BG
Pulmonology Department, Faculdade de Medicina, Universidade de São Paulo, SaoPaulo, Brazil. bruno.guedes2@terra.com.br
Santana
Alfredo Nicodemos Cruz
AN
Takagaki
Teresa Yae
TY
D000890:Anti-Infective Agents / Q000627:therapeutic use; D001989:Bronchiolitis Obliterans / Q000188:drug therapy; D005938:Glucocorticoids / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D016867:Immunocompromised Host; D008171:Lung Diseases / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology; D008297:Male; D008875:Middle Aged; D009617:Nocardia Infections / Q000175:diagnosis* / Q000188:drug therapy / Q000276:immunology; D009616:Nocardia asteroides / Q000302:isolation & purification; D011241:Prednisone / Q000009:adverse effects* / Q000627:therapeutic use; D017192:Skin Diseases, Bacterial / Q000175:diagnosis* / Q000188:drug therapy / Q000276:immunology; D015662:Trimethoprim, Sulfamethoxazole Drug Combination / Q000627:therapeutic use
D000890:Anti-Infective Agents; D005938:Glucocorticoids; D015662:Trimethoprim, Sulfamethoxazole Drug Combination; D011241:Prednisone