title: Ameloblastomas: a regional Latin-American multicentric study.
abstract: OBJECTIVE
  To classify 163 ameloblastoma cases according to the new WHO Classification of Odontogenic Tumours (2005) and analyse their clinical and microscopic features.
  
  
  METHODS
  We studied the clinico-pathological features of 163 ameloblastoma cases from nine regional Latin-American institutions from Mexico and Guatemala.
  
  
  RESULTS
  Ameloblastomas comprised 22.7% of all odontogenic tumours. The mean age was 41.4 years for solid ameloblastoma (SA) and 26.3 years for unicystic ameloblastoma (UA) (P < 0.001) and both sexes were almost equally affected. The mandible was mainly affected for both UA and SA. The mean size was 6.2 cm for SA and 6.3 cm for UA cases. The recurrence rate was 21.7% for SA and 12.6% for UA. UA was twice as more frequent than the solid variant.
  
  
  CONCLUSIONS
  In this study we found that UA was frequently misdiagnosed as SA; however, there are enough clinical and microscopic features that allow for an accurate differentiation between both types of ameloblastoma that should be recognized for surgical and prognostic purposes. In this study, SA was not found in patients younger than 20 years, UA had a constant myxoid stroma while mature connective tissue was more frequently associated with the solid type.
authors: Oral Pathology Laboratory, Facultad de Odontología, Universidad Nacional Autónoma de México, México, DF México. cledezma@servidor.unam.mx
authors: C
authors: C
authors: Ledesma-Montes
authors: A
authors: A
authors: Mosqueda-Taylor
authors: R
authors: R
authors: Carlos-Bregni
authors: E Romero
authors: ER
authors: de León
authors: J M
authors: JM
authors: Palma-Guzmán
authors: C
authors: C
authors: Páez-Valencia
authors: A
authors: A
authors: Meneses-García
mesh_terms: D000328:Adult; D000367:Age Factors; D000564:Ameloblastoma / Q000145:classification* / Q000473:pathology*; D005260:Female; D006166:Guatemala; D006801:Humans; D007573:Jaw Neoplasms / Q000145:classification* / Q000473:pathology*; D008297:Male; D008800:Mexico; D009364:Neoplasm Recurrence, Local; D012189:Retrospective Studies