[Neuroimaging and clinical predictors of hematoma enlargement in spontaneous intracerebral hemorrhage].
OBJECTIVE
To study the clinical and neuroimaging predictors of hematoma enlargement in spontaneous intracerebral hemorrhage (ICH).


METHODS
Ninety-eight patients with ICH within 4 hours of onset, 60 males and 38 females, aged 56+/-16, underwent the first CT examination at admission and the second CT examination 24 hours later to evaluate the occurrence of hematoma enlargement. Multivariate analysis was performed to assess the possible predictors.


RESULTS
Twenty-six of the 98 ICH patients (26.5%) developed hematoma enlargement. Multivariate analysis revealed that the following 4 factors were independently associated with hematoma enlargement: interval between first CT and onset, aniso-density hematoma, consciousness level at admission, and the history of cerebral infarction. A characteristic feature indicating the hematoma enlargement- "hematoma enlargement border" was found and named.


CONCLUSIONS
Hematoma enlargement after ICH has some clinical and neuroimaging predictors. The concepts and diagnostic criteria of aniso-density hematoma and hematoma enlargement border have been defined for the first time.
Lu
Jing-jing
JJ
Department of Neurosurgery, Tiantan Hospital, Beijing 100050, China.
Ji
Nan
N
Zhao
Yuan-li
YL
Wang
Shuo
S
Zhao
Ji-zong
JZ
D000328:Adult; D000368:Aged; D002543:Cerebral Hemorrhage / Q000150:complications / Q000000981:diagnostic imaging*; D005260:Female; D006406:Hematoma / Q000175:diagnosis / Q000000981:diagnostic imaging* / Q000209:etiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D012307:Risk Factors; D014057:Tomography, X-Ray Computed / Q000379:methods*