title: Synthesis and glycogen phosphorylase inhibitor activity of 2,3-dihydrobenzo[1,4]dioxin derivatives.
abstract: Novel 5-benzyl and 5-benzylidene-thiazolidine-2,4-diones carrying 2,3-dihydrobenzo[1,4]dioxin pharmacophore were synthesized and their glycogen phosphorylase inhibitor activity was also studied.
authors: Department of Organic Chemistry, University of Debrecen, H-4010, Debrecen, Hungary. juhaszl@delfin.unideb.hu
authors: László
authors: L
authors: Juhász
authors: Tibor
authors: T
authors: Docsa
authors: Attila
authors: A
authors: Brunyászki
authors: Pál
authors: P
authors: Gergely
authors: Sándor
authors: S
authors: Antus
mesh_terms: D004147:Dioxins / Q000138:chemical synthesis* / Q000494:pharmacology*; D004791:Enzyme Inhibitors / Q000138:chemical synthesis* / Q000494:pharmacology*; D024981:Glycogen Phosphorylase / Q000037:antagonists & inhibitors*; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry
chemical_list: C521468:2,3-dihydrobenzo(1,4)dioxin; D004147:Dioxins; D004791:Enzyme Inhibitors; D024981:Glycogen Phosphorylase