title: [Gabapentin (GBP) in panic disorders--case report].
abstract: Gabapentin is an anticonvulsant structurally similar to gamma - amino- butyric acid considered as the central acting GABA- analogue. It is used mostly as an antiepileptic agent. A constantly growing number of studies refer to its efficacy in the treatment of psychiatric disorders.
  
  
  OBJECTIVE
  To audit the effectiveness of the gabapentin used as adjunctive treatment of intensified panic disorder.
  
  
  METHODS
  6 patients (5 women, 1 man, of mean age 44.2 years) treated with gabapentin in combined therapy of a mean dose 300 mg/d, lasting on average 196 days.
  
  
  METHODS
  Patients were diagnosed using research criteria based on the ICD-10 and M.I.N.I.5.0.0.
  
  
  CONCLUSIONS
  Adverse events were not observed and an addition of gabapentin into treatment brings improvement of the clinical condition. Complete amelioration was detected in 4 of the 6 patients. In one single year of observation panic disorder relapses were not observed even though there was a discontinuation of treatment. The presented case reports show a possibility of successful treatment with gabapentin in severe panic disorders.
authors: Katedra i Klinka Psychiatrii AM w Lublinie, Głuska.
authors: Boiena
authors: B
authors: Spila
authors: Agnieszka
authors: A
authors: Szumiłło
mesh_terms: D000328:Adult; D000588:Amines / Q000008:administration & dosage*; D014151:Anti-Anxiety Agents / Q000008:administration & dosage*; D014150:Antipsychotic Agents / Q000008:administration & dosage*; D003509:Cyclohexanecarboxylic Acids / Q000008:administration & dosage*; D004359:Drug Therapy, Combination; D005260:Female; D000077206:Gabapentin; D006801:Humans; D008297:Male; D008875:Middle Aged; D016584:Panic Disorder / Q000188:drug therapy*; D012720:Severity of Illness Index; D016896:Treatment Outcome; D005680:gamma-Aminobutyric Acid / Q000008:administration & dosage*
chemical_list: D000588:Amines; D014151:Anti-Anxiety Agents; D014150:Antipsychotic Agents; D003509:Cyclohexanecarboxylic Acids; D005680:gamma-Aminobutyric Acid; D000077206:Gabapentin