title: Oral lesions in HIV-positive dental patients--one more argument for tobacco smoking cessation.
abstract: OBJECTIVE
  To determine the prevalence of oral lesions associated with human immunodeficiency virus (HIV) in a population of dental patients and analyze its association with psycho-social variables and biological markers.
  
  
  METHODS
  The dental charts of 415 dental patients consecutively treated between May and July 2005 in a dedicated HIV dental clinic were reviewed. Oral soft tissue examinations, psycho-social and medical variables were extracted and recorded for each patient. Ethnicity, gender, HIV treatment, peripheral CD(4) counts and tobacco usage were analyzed in correlation with oral lesions associated with HIV.
  
  
  RESULTS
  Fifty-five percent of all subjects had at least one oral lesion associated with HIV, with oral candidiasis, salivary gland enlargement and oral hairy leukoplakia being the most commonly observed conditions. Gender and ethnicity did not correlate with a higher prevalence in lesions. However, tobacco smoking correlated significantly with a higher prevalence of oral lesions, independent of CD(4) counts.
  
  
  CONCLUSIONS
  These findings suggest that oral lesions remain commonly observed morbidities among HIV-infected dental patients independent of gender and ethnicity and that tobacco usage is a major and often underestimated risk factor for those lesions.
authors: Department of Oral Medicine and Diagnostic Sciences, College of Dentistry, University of Illinois, Chicago, IL 60612-7213, USA. sroussih@uic.edu
authors: H Y
authors: HY
authors: Sroussi
authors: D
authors: D
authors: Villines
authors: J
authors: J
authors: Epstein
authors: M C F
authors: MC
authors: Alves
authors: M E A F
authors: ME
authors: Alves
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D023241:Antiretroviral Therapy, Highly Active; D002180:Candidiasis, Oral / Q000150:complications* / Q000209:etiology; D002648:Child; D005006:Ethnicity; D005260:Female; D015658:HIV Infections / Q000150:complications* / Q000188:drug therapy; D006801:Humans; D007972:Leukoplakia, Oral / Q000150:complications* / Q000209:etiology; D008297:Male; D008875:Middle Aged; D009062:Mouth Neoplasms / Q000150:complications* / Q000209:etiology; D012189:Retrospective Studies; D012307:Risk Factors; D012466:Salivary Gland Diseases / Q000150:complications* / Q000209:etiology; D012907:Smoking / Q000009:adverse effects; D012959:Socioeconomic Factors