The expanding spectrum of Galli-Galli disease.
Galli-Galli disease (GGD), a rare genodermatosis in the spectrum of reticulate hyperpigmentation, is regarded as an acantholytic variant of Dowling-Degos disease. We herein report two patients with GGD exhibiting erythematous scaly plaques and lentigo-like macules on the trunk and lower extremities, rather than the characteristic reticulate hyperpigmented macules of large body folds. Digitate elongations of rete ridges coupled with foci of acantholysis were the clues to the diagnosis. A high index of suspicion is needed to diagnose GGD that lacks the characteristic reticulate hyperpigmentation of large body folds.
El Shabrawi-Caelen
Laila
L
Department of Dermatology, University of Graz, Austria. laila.elshabrawicaelen@meduni-graz.at
Rütten
Arno
A
Kerl
Helmut
H
D000051:Acantholysis / Q000209:etiology / Q000473:pathology; D000368:Aged; D002881:Chromosomes, Human, Pair 12; D003937:Diagnosis, Differential; D005260:Female; D005799:Genes, Dominant; D006801:Humans; D053555:Keratin-5 / Q000235:genetics*; D009154:Mutation; D010859:Pigmentation Disorders / Q000150:complications / Q000175:diagnosis* / Q000235:genetics* / Q000473:pathology; D012867:Skin / Q000473:pathology
D053555:Keratin-5