[Surgery of residual masses after chemotherapy in patients with testicular cancer].
Advanced non seminomatous germ cell tumours are rare diseases affecting young men. Advanced disease is curable in 80% of the cases. The primary site of metastases is the retroperitoneal lymph nodes. Secondary metastatic sites are the lungs and mediastinal lymph nodes. Cisplatin-based chemotherapy has dramatically improved the prognosis of germ cell tumours, but surgery, when applicable, remains a central part of treatment. Forty five per cent and 10% of residual masses contain teratoma or active disease respectively. Residual masses of pure seminoma are removed only when postoperative pet-scan evaluation is positive or when they have grown during the follow-up period. All surgical procedures must be performed in a reference center.
Fléchon
Aude
A
Département de cancérologie médicale, Centre Léon-Bérard, Lyon. flechon@lyon.fnclcc.fr
Rivoire
Michel
M
Berger
Nicole
N
D000328:Adult; D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D001932:Brain Neoplasms / Q000188:drug therapy / Q000532:radiotherapy / Q000556:secondary / Q000601:surgery; D002945:Cisplatin / Q000008:administration & dosage / Q000627:therapeutic use*; D003131:Combined Modality Therapy; D018849:Controlled Clinical Trials as Topic; D005500:Follow-Up Studies; D006801:Humans; D008113:Liver Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary / Q000601:surgery; D008175:Lung Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary / Q000601:surgery; D008207:Lymphatic Metastasis; D008297:Male; D018365:Neoplasm, Residual / Q000601:surgery*; D009373:Neoplasms, Germ Cell and Embryonal / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000532:radiotherapy / Q000556:secondary* / Q000601:surgery*; D049268:Positron-Emission Tomography; D011183:Postoperative Complications; D011379:Prognosis; D011446:Prospective Studies; D011859:Radiography; D011879:Radiotherapy Dosage; D012187:Retroperitoneal Space; D018239:Seminoma / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000601:surgery; D013724:Teratoma / Q000601:surgery; D013736:Testicular Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000532:radiotherapy / Q000601:surgery*; D013997:Time Factors; D016896:Treatment Outcome
D000970:Antineoplastic Agents; D002945:Cisplatin