title: Multiple Aspergillus brain abscesses in immuno-competent patient with severe cranio-facial trauma.
abstract: Aspergillosis of the central nervous system (CNS) is a rare, but well described disease in immuno-competent patients. We present a 65-year-old patient who developed neuro-aspergillosis 10 months after severe cranio-facial trauma (Le Fort III). He was treated successfully with surgery including stereotactic drainage and, with Amphotericin B, Liposomal Amphotericin B, and Itraconazol.
authors: Department of Neurosurgery, University Hospital Dubrava, Zagreb, Croatia.
authors: T
authors: T
authors: Marinovic
authors: J
authors: J
authors: Skrlin
authors: M
authors: M
authors: Vilendecic
authors: K
authors: K
authors: Rotim
authors: G
authors: G
authors: Grahovac
mesh_terms: D000368:Aged; D000666:Amphotericin B / Q000008:administration & dosage; D000935:Antifungal Agents / Q000008:administration & dosage; D001922:Brain Abscess / Q000175:diagnosis / Q000188:drug therapy / Q000276:immunology* / Q000601:surgery; D002552:Cerebral Ventricles / Q000601:surgery; D002557:Cerebrospinal Fluid Shunts; D003131:Combined Modality Therapy; D004334:Drug Administration Schedule; D005151:Facial Injuries / Q000601:surgery*; D006801:Humans; D006849:Hydrocephalus / Q000601:surgery; D007121:Immunocompetence / Q000276:immunology*; D017964:Itraconazole / Q000008:administration & dosage; D008297:Male; D008440:Maxillary Fractures / Q000601:surgery*; D016921:Meningitis, Fungal / Q000175:diagnosis / Q000188:drug therapy / Q000276:immunology* / Q000601:surgery; D008866:Microsurgery; D009044:Motor Cortex / Q000601:surgery; D020953:Neuroaspergillosis / Q000175:diagnosis / Q000188:drug therapy / Q000276:immunology* / Q000601:surgery; D038361:Neuronavigation; D019340:Osteotomy, Le Fort; D011183:Postoperative Complications / Q000175:diagnosis / Q000188:drug therapy / Q000276:immunology* / Q000601:surgery; D012086:Reoperation; D012887:Skull Fractures / Q000601:surgery*; D014057:Tomography, X-Ray Computed
chemical_list: D000935:Antifungal Agents; D017964:Itraconazole; D000666:Amphotericin B