title: QTL modulating ear size and erectness in pigs.
abstract: Ear size and erectness are important conformation measurements in pigs. An F(2) population established by crossing European Large White (small, erect ears) with Chinese Meishan (large, flop ears) was used to study the genetic influence of the two ear traits for the first time. A linkage map incorporating 152 markers on 18 autosomal chromosomes was utilised in a genome scan for QTL. Significant QTL were found on SSC1, 5, 7, 9 and 12 for the two traits. The QTL on SSC5 and SSC7 had major effects and were significant at the genome-wide level (P < 0.01). The QTL on SSC1 for ear erectness also had a major effect and was genome-wide significant (P < 0.01). The 95% confidence interval (CI) of the ear size QTL on SSC5 spanned only 4 cM. The QTL on SSC7 for the two ear traits each had a CI of <20 cM, and their positions overlapped with those of the major QTL affecting subcutaneous fat depths on the same chromosome. This study provides insights on the complex genetic influences underlying pig ear traits and will facilitate positional candidate gene analysis to identify causative DNA variants.
authors: Roslin Institute (Edinburgh), Roslin, Midlothian EH25 9PS, Scotland, UK. wenhua.wei@bbsrc.ac.uk
authors: W H
authors: WH
authors: Wei
authors: D J
authors: DJ
authors: de Koning
authors: J C
authors: JC
authors: Penman
authors: H A
authors: HA
authors: Finlayson
authors: A L
authors: AL
authors: Archibald
authors: C S
authors: CS
authors: Haley
mesh_terms: D000818:Animals; D002874:Chromosome Mapping; D003433:Crosses, Genetic; D004423:Ear / Q000033:anatomy & histology* / Q000502:physiology; D023281:Genomics / Q000379:methods; D009929:Organ Size; D040641:Quantitative Trait Loci; D034421:Sus scrofa / Q000235:genetics*