title: [Early detection of ischemic lesions in the super-acute phase of ischemic cerebrovascular diseases by imaging].
abstract: A thrombolytic agent, recombinant tissue plasminogen activator (rt-PA), was recently approved in Japan for use on patients within 3 hrs of the onset of cerebral infarction. In order to salvage cerebral tissue after an ischemic insult, it is crucial to detect the ischemic lesion before it becomes irreversible and to detect the core and penumbra areas of the lesion for guidance in selecting the suitable therapy. In this symposium we discuss the detection of ischemic lesions using plain CT, perfusion CT, and MRI. In the section on plain CT, we present a typical case with early CT signs. In the section on perfusion CT, we report on the feasibility and limitation of the technique for the diagnosis of acute cerebral infarction. In the section on MRI, we study the usefulness of DWI for the early and highly reliable detection of ischemic stroke.
authors: Division of Neurology, Nephrology and Rheumatology, Internal Medicine, Nippon Medical School.
authors: Yasuo
authors: Y
authors: Katayama
authors: Hironaka
authors: H
authors: Igarashi
authors: Yuichi
authors: Y
authors: Komaba
authors: Tatsuo
authors: T
authors: Ohtori
authors: Hidenori
authors: H
authors: Nakamura
authors: Hiroshi
authors: H
authors: Hagiwara
mesh_terms: D002544:Cerebral Infarction / Q000175:diagnosis*; D006801:Humans; D008279:Magnetic Resonance Imaging; D014057:Tomography, X-Ray Computed