title: [Cotrimoxazole Pneumocystis jiroveci pneumonia treatment failure: co-infection cytomegalovirus role?].
abstract: Pneumocystis jiroveci pneumonia is a classic opportunist infection affecting AIDS patients. However it is less frequent since systematic prophylaxis and antiretroviral therapies. Treatment resistance is rare in France. We report the case of a severe Pneumocystis jiroveci pneumonia with treatment resistance to standard treatment and fatal outcome. The different causes of treatment resistance, notably the role of CMV co-infection, were reviewed and discussed.
authors: Service d'anesthésie et de réanimation, CHU Jean-Verdier, APHP, Bondy, France.
authors: J
authors: J
authors: Scemama
authors: R
authors: R
authors: Amathieu
authors: L
authors: L
authors: Tual
authors: C
authors: C
authors: Fessenmeyer
authors: J
authors: J
authors: Stirnemann
authors: G
authors: G
authors: Dhonneur
mesh_terms: D000890:Anti-Infective Agents / Q000494:pharmacology*; D003586:Cytomegalovirus Infections / Q000150:complications*; D024881:Drug Resistance, Bacterial; D017809:Fatal Outcome; D006801:Humans; D008297:Male; D008875:Middle Aged; D045363:Pneumocystis carinii; D011020:Pneumonia, Pneumocystis / Q000188:drug therapy* / Q000821:virology*; D015662:Trimethoprim, Sulfamethoxazole Drug Combination / Q000494:pharmacology*
chemical_list: D000890:Anti-Infective Agents; D015662:Trimethoprim, Sulfamethoxazole Drug Combination