Unilateral hypopyon in a child as a first and sole presentation in relapsing acute lymphoblastic leukemia.
Ocular manifestations form a part of the spectrum of varied clinical presentations in leukemias. Most of the ophthalmic manifestations are related to central nervous system leukemia and bone marrow relapse. We report a case of acute unilateral hypopyon uveitis as an initial presenting feature of relapsing acute lymphoblastic leukemia (ALL) in a pediatric patient. Anterior chamber paracentesis was performed in a four-year-old male child presenting with unilateral treatment-resistant hypopyon after remission of ALL. Examination of aqueous humor aspirate revealed presence of malignant cells. Atypical hypopyon, even unilateral can be an indication of relapsing ALL in a child.
Wadhwa
Neeraj
N
Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India. drneerajwadhwa@rediffmail.com
Vohra
Rajpal
R
Shrey
Dinesh
D
Iyer
V K
VK
Garg
Satpal
S
D000867:Anterior Chamber; D002675:Child, Preschool; D006801:Humans; D008297:Male; D019152:Paracentesis; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000150:complications* / Q000175:diagnosis / Q000473:pathology; D012008:Recurrence; D013492:Suppuration / Q000175:diagnosis / Q000473:pathology; D014605:Uveitis / Q000209:etiology*