title: HTS, chemical hybridization, and drug design identify a chemically unique antituberculosis agent-coupling serendipity and rational approaches to drug discovery.
authors: Institute for Tuberculosis Research, College of Pharmacy, University of Illinois at Chicago, 833 South Wood Street, Chicago IL 60612, USA.
authors: Jialin
authors: J
authors: Mao
authors: Baojie
authors: B
authors: Wan
authors: Yuehong
authors: Y
authors: Wang
authors: Scott G
authors: SG
authors: Franzblau
authors: Alan P
authors: AP
authors: Kozikowski
mesh_terms: D000818:Animals; D000995:Antitubercular Agents / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D002460:Cell Line; D002522:Chlorocebus aethiops; D016503:Drug Delivery Systems; D015195:Drug Design; D007555:Isoxazoles / Q000737:chemistry; D007930:Leucine / Q000031:analogs & derivatives / Q000138:chemical synthesis; D015767:Mefloquine / Q000737:chemistry; D051379:Mice; D008826:Microbial Sensitivity Tests; D009169:Mycobacterium tuberculosis / Q000187:drug effects*; D054852:Small Molecule Libraries / Q000737:chemistry / Q000494:pharmacology; D014709:Vero Cells
chemical_list: D000995:Antitubercular Agents; D007555:Isoxazoles; D054852:Small Molecule Libraries; D007930:Leucine; C013086:leucinamide; D015767:Mefloquine