title: Mimicking methylated histones.
abstract: Histones with specific patterns of lysine methylation help to define how their associated DNA is used. A recent semisynthetic strategy for generating histone proteins that contain methyl-lysine analogues at specific sites will provide researchers with the materials to further elucidate the role of these modifications.
authors: Department of Biochemistry, Biophysics, and Molecular Biology, Iowa State University, 4214 Molecular Biology Building, Ames, Iowa 50011, USA. knaak@iastate.edu
authors: Michael A
authors: MA
authors: Shogren-Knaak
mesh_terms: D000595:Amino Acid Sequence; D006657:Histones / Q000502:physiology*; D008239:Lysine / Q000378:metabolism*; D008745:Methylation
chemical_list: D006657:Histones; D008239:Lysine