Urine proteomics--prospects for future diagnostics.
This brief overview of the potential diagnostic, prognostic and pathophysiological value of studies into the urine proteome describes hypothesis-driven investigations of individual proteins and proteome-wide search for urinary biomarkers of various diseases and their progression. It is intended to illustrate the recent progress in the area of urine proteomics and proselytize for the promise of this centuries-old technique of uroscopy, yet to reveal its secrets, using modem approaches.
O'Riordan
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Department of Medicine and Renal Research Institute, New York Medical College, BSB C-23, Valhalla, NY 10595, USA.
Addabbo
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Goligorsky
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D000818:Animals; D051399:Aquaporin 2 / Q000652:urine; D015415:Biomarkers / Q000652:urine*; D006801:Humans; D007674:Kidney Diseases / Q000652:urine; D007680:Kidney Neoplasms / Q000652:urine; D016030:Kidney Transplantation / Q000502:physiology; D011507:Proteinuria / Q000652:urine*; D040901:Proteomics; D014511:Uremia / Q000652:urine; D014883:Water-Electrolyte Imbalance / Q000652:urine
D051399:Aquaporin 2; D015415:Biomarkers