title: Are we complying with NICE guidelines on the use of prostaglandin E2 for induction of labour? A survey of obstetric units in the UK.
abstract: To determine whether obstetric units in the UK comply with the recommendations by the National Institute for Clinical Excellence (NICE) on the maximum doses of intravaginal prostaglandin for induction of labour, a cross-sectional telephone survey of all obstetric units in the UK listed on Dr Foster's website was undertaken. The maximum doses recommended by NICE were exceeded by 86.4% (76/88) and 61.1% (55/90) of units that use intravaginal prostaglandin tablet and intravaginal prostaglandin gel, respectively. Units that use prostaglandin tablets were four times more likely to exceed the recommended maximum dose (OR = 4.03, 95% CI, 1.9 - 8.4), six times more likely to use 50% or more of the recommended maximum dose for nulliparous women (OR = 5.9, 95% CI, 3.1 - 11.0), and six times more likely to use 50% or more of the recommended maximum dose for multiparous women (OR = 6.5, 95% CI, 3.0 - 13.9). A majority of obstetric units in the UK exceed the maximum doses of intravaginal prostaglandin recommended by NICE for induction of labour.
authors: Women's Health Division, Barnet and Chase Farm Hospitals NHS Trust, Chase Farm Hospital, The Ridgeway, Enfield, UK. dseloojeme@aol.com
authors: D
authors: D
authors: Selo-Ojeme
authors: P
authors: P
authors: Pisal
authors: O
authors: O
authors: Barigye
authors: R
authors: R
authors: Yasmin
authors: A
authors: A
authors: Jackson
mesh_terms: D015232:Dinoprostone; D005260:Female; D019983:Guideline Adherence; D019538:Health Care Surveys; D006801:Humans; D007751:Labor, Induced / Q000592:standards*; D010120:Oxytocics; D017410:Practice Guidelines as Topic; D011247:Pregnancy; D006113:United Kingdom
chemical_list: D010120:Oxytocics; D015232:Dinoprostone