14th International HLA and Immunogenetics Workshop: report on non-classical class I genes.
Non-classical class I genes are encoding for cell surface proteins that have largely yet unknown functions. Although some of these proteins (human leukocyte antigens E, F and G) have been shown to present peptides, their polymorphism is very restricted at the peptide-binding region. In the present Workshop, several papers were presented addressing detection, evolutive and functional issues of these proteins. The general inhibitory immunological function of these proteins is put forward.
Arnaiz-Villena
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Departamento de Inmunologia, Facultad de Medicina, Universidad Complutense, Madrid, Spain. aarnaiz@med.ucm.es
D005805:Genes, MHC Class I; D006680:HLA Antigens / Q000235:genetics*; D006801:Humans; D007125:Immunogenetics
D006680:HLA Antigens