title: [Automatic auditory information management in panic disorder patients: an event-related potentials study].
abstract: OBJECTIVE
  To investigate the characteristics of automatic auditory information management in sufferers of panic disorder (PD).
  
  
  METHODS
  Mismatch negativity (MMN), as a component of event-related potentials, was recorded from 15 PD patients, 8 males and 7 females, aged 40 +/- 12, and 15 sex, and aged-matched controls. Repeated measures ANOVA was used on 4 representative electrodes: T3, T4, F3, and F4.
  
  
  RESULTS
  Compared with the normal controls, the PD patients showed significant enlargement of MMN amplitude in 60 - 210 ms latency windows (60 - 110 ms: F(1, 28) = 11.413, P = 0.02; 110 - 160 ms: F(1, 28) = 6.639, P = 0.016; 160 - 210 ms: F(1, 28) = 5.758, P = 0.023), and exhibited early (60 - 160 ms) left encephalic region predominant effect.
  
  
  CONCLUSIONS
  PD patients may deal excessive automatic processing of the auditory information changes which may assist in offering new objective evidence to understand the etiology of PD.
authors: Department of Neurology, First Affiliated Hospital of Dalian Medical University, Dalian 116011, China.
authors: Qing-dong
authors: QD
authors: Li
authors: Jing
authors: J
authors: Xu
authors: Lun
authors: L
authors: Zhao
authors: Xiao-wei
authors: XW
authors: Liu
authors: Bing-wei
authors: BW
authors: Zhang
mesh_terms: D000328:Adult; D000704:Analysis of Variance; D005072:Evoked Potentials, Auditory / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D016584:Panic Disorder / Q000503:physiopathology* / Q000523:psychology