Two new antifungal alkaloids produced by Streptoverticillium morookaense.
A new carbazole alkaloid, streptoverticillin, and a new 2-azetidinone, streptoverticillinone, along with three known cyclodipeptides were isolated from the mycelial solid culture of Streptoverticillium morookaense. Their structures were elucidated by analysis of 1D and 2D NMR, mass spectra and optical rotation data. Two new compounds exhibited antifungal activity against Peronophythora litchii.
Feng
Na
N
South China Botanical Garden, Chinese Academy of Sciences, Tianhe District, Guangzhou, China.
Ye
Wanhui
W
Wu
Ping
P
Huang
Yicun
Y
Xie
Haihui
H
Wei
Xiaoyi
X
D000470:Alkaloids / Q000096:biosynthesis* / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D000935:Antifungal Agents / Q000737:chemistry / Q000302:isolation & purification / Q000378:metabolism* / Q000494:pharmacology*; D002227:Carbazoles / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D005658:Fungi / Q000187:drug effects*; D032125:Litchi / Q000382:microbiology; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry / Q000379:methods; D008826:Microbial Sensitivity Tests; D009904:Optical Rotation; D010935:Plant Diseases / Q000382:microbiology; D011759:Pyrrolidines / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D013302:Streptomyces / Q000254:growth & development / Q000378:metabolism*
D000470:Alkaloids; D000935:Antifungal Agents; D002227:Carbazoles; D011759:Pyrrolidines; C520913:streptoverticillin; C520914:streptoverticillinone