Neuroregulator RET initiates Peyer's-patch tissue genesis.
The tyrosine kinase receptor RET regulates the intestinal nervous system. A recent paper by Veiga-Fernandes et al. (2007) demonstrates that RET is also involved in the intestinal immune system through the initiation of Peyer's-patch tissue genesis.
Fukuyama
Satoshi
S
Division of Mucosal Immunology, Department of Microbiology and Immunology, The Institute of Medical Science, The University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo, 108-8639, Japan.
Kiyono
Hiroshi
H
D000818:Animals; D007422:Intestines / Q000276:immunology* / Q000294:innervation; D008297:Male; D010581:Peyer's Patches / Q000254:growth & development*; D051096:Proto-Oncogene Proteins c-ret / Q000235:genetics / Q000502:physiology*
D051096:Proto-Oncogene Proteins c-ret; C494999:Ret protein, mouse