title: Effect of population aging on the international organ donation rates and the effectiveness of the donation process.
abstract: This study analyzed the effect of population aging on organ donation for transplants in 43 countries and on the effectiveness of the donation process by comparing the results between Spain and the United States. The percentage of the population aged 65 or over accounted for 33% of the difference in the donation rates between the countries and for 91% of the variation in the rates after age adjustment. However, the level of aging of the Spanish (16.5%) and American (12.3%) populations failed to account for the percentages of deceased donors 65 or over (28% vs. 10%), due to the different age-specific donation rates, much higher in Spain above 50 years. These differences lead to a higher effectiveness of the process in the United States (3.1 transplanted organs per donor vs. 2.5 in Spain), though at lower rates of transplant per million population (73 vs. 87). We conclude that older populations have a greater donation potential as donation rates are strongly associated with population aging. It should therefore be mandatory to adjust donation rates for age before making comparisons. Additionally, effectiveness decreases with older donors, so age should be considered when establishing standards relating to organ donation and effectiveness of the process.
authors: Andalusian Transplant Coordination Office, Seville, Spain. natividad.cuende.sspa@juntadeandalucia.es
authors: N
authors: N
authors: Cuende
authors: J I
authors: JI
authors: Cuende
authors: J
authors: J
authors: Fajardo
authors: J
authors: J
authors: Huet
authors: M
authors: M
authors: Alonso
mesh_terms: D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000502:physiology*; D002102:Cadaver; D002648:Child; D006801:Humans; D019520:Living Donors / Q000706:statistics & numerical data*; D008875:Middle Aged; D016377:Organ Transplantation / Q000401:mortality / Q000706:statistics & numerical data*; D011157:Population Dynamics; D014019:Tissue Donors / Q000706:statistics & numerical data*; D009927:Tissue and Organ Procurement / Q000379:methods*