[Discrimination of heterozygote currency of ataxia-telangiectasia by indirect immunofluorescent analysis].
The qualitative differences in P53 protein stabilization after ionizing irradiation in different doses were found in cells of members of ataxia-telangiectasia (AT) family--proband AT6SP, her sister AT(S)6SP and father AT(F)6SP. The method of indirect immunofluorescence with confocal microscopy was used.
Spivak
I M
IM
Smirnova
N V
NV
Pleskach
N M
NM
Ledashcheva
T A
TA
Mikhel'son
V M
VM
D000293:Adolescent; D000328:Adult; D001260:Ataxia Telangiectasia / Q000235:genetics* / Q000378:metabolism; D002478:Cells, Cultured; D002648:Child; D004307:Dose-Response Relationship, Radiation; D005260:Female; D005455:Fluorescent Antibody Technique; D005720:Gamma Rays; D006579:Heterozygote; D006801:Humans; D008297:Male; D008875:Middle Aged; D016159:Tumor Suppressor Protein p53 / Q000032:analysis / Q000378:metabolism / Q000528:radiation effects
D016159:Tumor Suppressor Protein p53