A novel cytotoxic lignan from Seseli annuum L.
A new tetrahydrofuranoid lignan named seselinone was isolated from the aerial parts of Seseli annuum, together with three known lignans (eudesmin, magnone A and hernone) and prenylated coumarin umbelliprenin. Seselinone and eudesmin showed cytotoxic activity against C6 rat glioma cell cultures.
Vucković
Ivan
I
Institute for Chemistry, Technology and Metallurgy, Njegoseva 12, 11000 Belgrade, Serbia.
Trajković
Vladimir
V
Macura
Slobodan
S
Tesević
Vele
V
Janaćković
Peda
P
Milosavljević
Slobodan
S
D000818:Animals; D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry* / Q000633:toxicity*; D019661:Apiaceae / Q000737:chemistry*; D045744:Cell Line, Tumor; D005910:Glioma / Q000473:pathology*; D017705:Lignans / Q000737:chemistry / Q000633:toxicity*; D035261:Plant Components, Aerial / Q000737:chemistry; D051381:Rats
D000972:Antineoplastic Agents, Phytogenic; D017705:Lignans; C523277:seselinone