A woman with Cushing's syndrome after use of an Indonesian herb: a case report.
A 69-year-old woman developed Cushing's syndrome after long-term use of Sinatren, an Indonesian over the-counter drug, which was pharmacologically analysed three times before the correct content was discovered. After discontinuation she developed adrenal insufficiency, for which she needed substitution of steroids. Physicians should be aware of the presence of corticosteroids in over-the-counter products, that are not mentioned on the instruction leaflet.
Oldenburg-Ligtenberg
P C
PC
Department of Internal Medicine, Meander Medical Centre, Amersfoort, The Netherlands. pc.oldenburg@meandermc.nl
van der Westerlaken
M M L
MM
D000305:Adrenal Cortex Hormones / Q000009:adverse effects*; D000309:Adrenal Insufficiency / Q000139:chemically induced* / Q000175:diagnosis; D000368:Aged; D003480:Cushing Syndrome / Q000139:chemically induced* / Q000175:diagnosis; D004485:Eczema / Q000188:drug therapy*; D005260:Female; D006801:Humans; D007214:Indonesia; D008487:Medical History Taking; D004366:Nonprescription Drugs / Q000009:adverse effects / Q000737:chemistry*; D008517:Phytotherapy / Q000009:adverse effects*; D010936:Plant Extracts / Q000009:adverse effects / Q000737:chemistry*; D012651:Self Medication
D000305:Adrenal Cortex Hormones; D004366:Nonprescription Drugs; D010936:Plant Extracts