[Progresses of prospects for hypoxic preconditioning].
Hypoxic preconditioning (HPC), a strategy of intrinsic cytoprotection developed in biological evolution, is designed to be motivated by repetitive exposure of organism, organ, tissue and cell to condition of hypoxia. The effect of HPC is broadened remotely to protect different organ-tissues in other regions ( remote/ectopic HPC, r/e HPC ) and crossly to resist a variety of stresses other than hypoxia ( cross/ pluripotential HPC, c/pHPC ) from protection of original local in situ organ-tissue repeatedly exposed to hypoxia (local/in situ HPC, l/Ii HPC). More spaces for development of feasibility and applicability in the research on HPC would be expected based on the progresses recently available.
Lu
Guo-Wei
GW
Institute for Hypoxia Medicine, Capital Medical University, Beijing 100069, China.
D000818:Animals; D015687:Cell Hypoxia; D019610:Cytoprotection; D002534:Hypoxia, Brain / Q000503:physiopathology*; D019194:Ischemic Preconditioning; D051379:Mice