title: Postinfectious bronchiolitis obliterans accompanied by pulmonary hemosiderosis in childhood.
abstract: In the present report, we describe an unusual presentation of post-infectious bronchiolitis obliterans accompanied by pulmonary hemosiderosis in a nine-year-old boy with persistent respiratory symptoms subsequent to an episode of acute bronchiolitis occurring at the age of seven months. After the episode, the persistent respiratory symptoms worsened significantly, and, by the age of seven, the patient began to have difficulty breathing after minimal exertion. Computed tomography of the chest presented findings consistent with bronchiolitis obliterans. Open lung biopsy revealed numerous hemosiderin-laden macrophages, as well as other findings consistent with bronchiolitis obliterans. Pulmonary hemosiderosis can occasionally be accompanied by bronchiolitis obliterans in children with severe sequelae after an episode of viral infection.
authors: Department of Pediatrics, Pediatric Pulmonology Sector, Pontifícia Universidade Católica do Rio Grande doSul, Hospital São Lucas, Porto Alegre, Brazil.
authors: Leonardo Araújo
authors: LA
authors: Pinto
authors: Anick
authors: A
authors: Oliveira
authors: Sintia
authors: S
authors: Collaziol
authors: Paulo Márcio
authors: PM
authors: Pitrez
authors: Marcus
authors: M
authors: Jones
authors: João Carlos
authors: JC
authors: Prolla
authors: Marisa
authors: M
authors: Dolhnikoff
authors: Renato T
authors: RT
authors: Stein
mesh_terms: D000208:Acute Disease; D000402:Airway Obstruction / Q000209:etiology* / Q000628:therapy; D001706:Biopsy; D001989:Bronchiolitis Obliterans / Q000150:complications* / Q000175:diagnosis / Q000473:pathology; D002648:Child; D006486:Hemosiderosis / Q000150:complications* / Q000175:diagnosis / Q000473:pathology; D006801:Humans; D008171:Lung Diseases / Q000150:complications / Q000175:diagnosis / Q000473:pathology; D008297:Male; D010102:Oxygen Inhalation Therapy; D012129:Respiratory Function Tests; D014057:Tomography, X-Ray Computed