title: Severe oligoasthenoteratozoospermias, secretory and obstructive azoospermias: motility as a criterion of sperm viability.
abstract: OBJECTIVE
  Comparison of pregnancy rates in cases of Secretory Azoospermias (SA), Obstructive Azoospermias (OA) and severe Oligoasthenoteratozoospermias (OATZ). Evaluation of sperm motility as a quality criterion.
  
  
  METHODS
  In SA cases (n = 35), 9 samples were cryopreserved. In OA cases (epididymal aspiration: n = 91; testicular biopsy: n = 206), all samples were cryopreserved. 596 OATZ ejaculates were included.
  
  
  RESULTS
  In SA cases, 2 pregnancies were achieved from 9 ICSI cycles. In OA, motile sperm rates were higher in testicular biopsies. After thawing sperm motility was not different between testicular and epididymal origin. 2 pregnancies were achieved with immotile testicular sperm after thawing, but none with immotile epididymal sperm. In OATZ cases, one pregnancy was obtained from the 9 cryopreserved ejaculates and 35.3% with fresh motile sperm.
  
  
  CONCLUSIONS
  In SA cases, the use of donor sperm is recommended due to the lower pregnancy rate achieved. Motility, before and after cryopreservation, as a criterion of sperm viability is discussed and its use should be reconsidered in some cases.
authors: Human Assisted Reproduction Unit, La Fe University Hospital of Valencia, Valencia, Spain. molina_inmbot@gva.es
authors: I
authors: I
authors: Molina
authors: J
authors: J
authors: Alfonso
authors: C C
authors: CC
authors: Duque
authors: L
authors: L
authors: García-Reboll
authors: M
authors: M
authors: Pérez-Camps
authors: A
authors: A
authors: Romeu
mesh_terms: D053713:Azoospermia / Q000473:pathology / Q000503:physiopathology*; D001706:Biopsy; D002470:Cell Survival; D015925:Cryopreservation; D004542:Ejaculation; D004822:Epididymis / Q000473:pathology; D005260:Female; D006801:Humans; D008297:Male; D009845:Oligospermia / Q000473:pathology / Q000503:physiopathology*; D011247:Pregnancy; D011256:Pregnancy Outcome; D020554:Sperm Injections, Intracytoplasmic; D013081:Sperm Motility; D013094:Spermatozoa / Q000166:cytology*; D013737:Testis / Q000473:pathology