[Functional significance of monoamine- and aminoacidergic mechanisms of dorsal pallidum in anxiety of different aversive genesis].
Microinjections of serotonin and glutamine acid into the globus pallidus reveal antiaversive properties of these subsrances in the test with avoiding "threatening situation" but not "illuminated site" test under conditions of rats' free choice between light and dark sites. Dopamine and GABA injected locally into this formation of basal ganglia do not affect the mechanisms of voluntary movement, but counteract the conditions of anxiety in both models of behavior. The results testify to unequal involvement of neurotransmitter systems of the dorsal pallidum into operative regulation of behavior with changes of aversive stimulus modality.
Talalaenko
A N
AN
Krivobok
G K
GK
Bulgakova
N P
NP
Pankrat'ev
D V
DV
D000596:Amino Acids / Q000494:pharmacology / Q000502:physiology; D000818:Animals; D001007:Anxiety / Q000209:etiology / Q000503:physiopathology* / Q000523:psychology; D001522:Behavior, Animal; D015306:Biogenic Monoamines / Q000494:pharmacology / Q000502:physiology*; D004924:Escape Reaction / Q000187:drug effects; D005917:Globus Pallidus / Q000187:drug effects / Q000502:physiology / Q000503:physiopathology*; D018698:Glutamic Acid / Q000494:pharmacology / Q000502:physiology*; D008297:Male; D051381:Rats; D012701:Serotonin / Q000494:pharmacology
D000596:Amino Acids; D015306:Biogenic Monoamines; D012701:Serotonin; D018698:Glutamic Acid