[Transient sick sinus syndrome by oral intake of high dose dehydrocodeine for postherpetic neuralgia].
An 88-year-old man was admitted to the intensive care unit after the ingestion of 150 mg of dehydrocodeine. The ECG showed severe brodycardia and he was diagnosed as sick sinus syndrome. The recovering of sinus node function took 5 days after the ingestion. The complication observed suggests that transient hypoxia induced by ingestion of high dose DHC had affected sinus node.
Ariyama
Jun
J
Department of Anesthesiology and Pain Clinic, Tonami General Hospital, Tonami.
Shibata
Keizo
K
Saito
Shinsuke
S
Sugimoto
Yuji
Y
Imanishi
Hirokazu
H
Tooyama
Yoshiko
Y
D000369:Aged, 80 and over; D000701:Analgesics, Opioid / Q000008:administration & dosage / Q000009:adverse effects*; D003061:Codeine / Q000008:administration & dosage / Q000009:adverse effects / Q000031:analogs & derivatives*; D004562:Electrocardiography; D006801:Humans; D008297:Male; D051474:Neuralgia, Postherpetic / Q000188:drug therapy*; D012804:Sick Sinus Syndrome / Q000139:chemically induced* / Q000175:diagnosis / Q000628:therapy
D000701:Analgesics, Opioid; C014481:dihydrocodeine; D003061:Codeine