Antigen to the node: B cells go native.
The participation of B and T cells in an immune response requires their separate activation by different forms of the target antigen. In this issue of Immunity, Pape et al. (2007) describe antigen entry into the B cell areas in the lymph node without degradation or cellular assistance.
Tarlinton
David
D
The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville 3050, Australia. tarlinton@wehi.edu.au
Lew
Andrew
A
D000818:Animals; D000941:Antigens / Q000276:immunology*; D001402:B-Lymphocytes / Q000276:immunology*; D006801:Humans; D008198:Lymph Nodes / Q000166:cytology / Q000276:immunology*; D008213:Lymphocyte Activation
D000941:Antigens