Vaccine-associated paralytic poliomyelitis: a case report of flaccid monoparesis after oral polio vaccine.
This report describes a case of acute flaccid paralysis after administration of oral polio vaccine (OPV). A 4 month-old male patient with the decreased movement of left lower extremity for 1 month was transferred to the Department of Pediatrics. He received OPV with DTaP at 2 months of age. Flaccid paralysis was detected 4 weeks after OPV immunization. Attempts to isolate Sabin-like viruses in the two stool and CSF samples failed because those specimens were collected more than 2 month after the onset of paralysis. Hypotonic monoparesis (GIV/V), hypotonia and atrophy on the left lower extremity, and ipsilateral claw foot persisted for more than 18 months, while we followed him with rehabilitation therapy. This is the first case of officially approved, recipient vaccine-associated paralytic poliomyelitis in Korea.
Kim
Sun Jun
SJ
Department of Pediatrics, Chonbuk National University, Medical School, Jeonju, Korea. sunjun@chonbuk.ac.kr
Kim
Sung Han
SH
Jee
Young Mee
YM
Kim
Jung Soo
JS
D006801:Humans; D007223:Infant; D008297:Male; D010264:Paraplegia / Q000139:chemically induced* / Q000175:diagnosis / Q000534:rehabilitation; D011051:Poliomyelitis / Q000139:chemically induced* / Q000175:diagnosis / Q000534:rehabilitation; D011055:Poliovirus Vaccine, Oral / Q000009:adverse effects*
D011055:Poliovirus Vaccine, Oral