title: [Purpura fulminans due to pneumococcal pneumonia in a healthy adult: a case report].
abstract: We report a case of infectious purpura fulminans due to pneumococcal pneumonia in a 61-year-old man presenting multiple organ failure and pneumococcal bacteremia secondary to pneumonia on admission. His lower limbs showed rapidly progressive purpura and symmetrical dry gangrene. He had no history of or apparent immunodeficiency, including asplenia, in abdominal ultrasonography. Despite of therapy, he died on day 15 after admission. Infectious purpura fulminans involves skin lesions with severe infection often accompanied by disseminated intravascular coagulation and septic shock. Although it occurs mainly in childhood, especially as a complication of Neisseria meningitis or Varicella virus infection, it has also been reported in adult, as a rare complication of invasive pneumococcal infection. Most had immunodeficiency such as asplenia or postsplenectomy. Purpura fulminans in a previously healthy adult is very rare and this is insofar as we know, the first report in Japan detailing the development from pneumococcal pneumonia.
authors: Department of Respiratory medicine and Allergy, Komaki Municipal Hospital.
authors: Kazuto
authors: K
authors: Takada
authors: Shuuichi
authors: S
authors: Matsumoto
authors: Tetsuo
authors: T
authors: Hiramatsu
authors: Eiji
authors: E
authors: Kojima
authors: Hiroaki
authors: H
authors: Watanabe
mesh_terms: D006801:Humans; D011695:IgA Vasculitis / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D009102:Multiple Organ Failure; D011018:Pneumonia, Pneumococcal / Q000150:complications*