[The product specificity evolution of cyclodextrin glucanotransferase: problems and challenges].
Cyclodextrin glucanotransferase, the essential enzyme for the production of cyclodextrins, has become the focus of scientific research nowadays. Although many related enzyme properties are well known, the crucial factors in product specificity determination remain to be answered. Here, the recent research progresses of cyclodextrin glucanotransferase, especially those about the evolution of product specificity, were reviewed, and the scientific problems were discussed.
Zhao
Xin-Shuai
XS
Life Science School, Shandong University, Jinan 250100, China.
Wang
Zhan-Kun
ZK
Qi
Qing-Sheng
QS
D019843:Archaeal Proteins / Q000235:genetics / Q000378:metabolism*; D001407:Bacillus / Q000201:enzymology / Q000235:genetics; D001426:Bacterial Proteins / Q000235:genetics / Q000378:metabolism*; D055162:Biocatalysis; D003505:Cyclodextrins / Q000378:metabolism*; D019143:Evolution, Molecular; D005964:Glucosyltransferases / Q000145:classification / Q000235:genetics / Q000378:metabolism*; D009154:Mutation; D046950:Thermoanaerobacterium / Q000201:enzymology / Q000235:genetics; D019712:Thermococcus
D019843:Archaeal Proteins; D001426:Bacterial Proteins; D003505:Cyclodextrins; D005964:Glucosyltransferases; C019963:cyclomaltodextrin glucanotransferase