title: Shedding of Escherichia coli O157:H7 in calves is reduced by prior colonization with the homologous strain.
abstract: Enterohemorrhagic Escherichia coli O157:H7 has a natural reservoir in the intestinal tracts of cattle. Colonization is asymptomatic and transient, but it is not clear if protective immunity is induced. This study demonstrates that prior colonization induces humoral immune responses to bacterial antigens and reduces bacterial shedding after experimental challenge with the homologous strain.
authors: Animal Health Group, Scottish Agricultural College, Edinburgh EH9 3JG, UK. stuart.naylor@sac.ac.uk
authors: Stuart W
authors: SW
authors: Naylor
authors: Allen
authors: A
authors: Flockhart
authors: Pablo
authors: P
authors: Nart
authors: David G E
authors: DG
authors: Smith
authors: John
authors: J
authors: Huntley
authors: David L
authors: DL
authors: Gally
authors: J Christopher
authors: JC
authors: Low
mesh_terms: D000818:Animals; D000907:Antibodies, Bacterial / Q000097:blood; D002417:Cattle; D002418:Cattle Diseases / Q000276:immunology / Q000382:microbiology*; D004797:Enzyme-Linked Immunosorbent Assay; D004927:Escherichia coli Infections / Q000276:immunology / Q000382:microbiology / Q000662:veterinary*; D019453:Escherichia coli O157 / Q000276:immunology* / Q000302:isolation & purification*; D005243:Feces / Q000382:microbiology*; D007070:Immunoglobulin A / Q000097:blood; D007074:Immunoglobulin G / Q000097:blood
chemical_list: D000907:Antibodies, Bacterial; D007070:Immunoglobulin A; D007074:Immunoglobulin G