title: Is bacterial colonisation of the tonsillar fossa a factor in post-tonsillectomy haemorrhage?
abstract: OBJECTIVE
  To identify if there is a link between bacterial colonisation of the tonsillar fossa and post-tonsillectomy haemorrhage.
  
  
  METHODS
  Prospective non-interventional study of 105 patients who underwent tonsillectomy during a seven-month period. The study took place in a secondary care centre, the West Middlesex University Hospital.
  
  
  METHODS
  The participants were 105 patients who consecutively underwent tonsillectomy. The exclusion criteria were any patients with suspected or known malignancy, or known bleeding dyscrasias. The participants underwent microbiological sampling of the tonsil pre-operatively.
  
  
  METHODS
  The outcome measures were primary or secondary bleeding, defined as any evidence of haemorrhage in the tonsillar fossae.
  
  
  RESULTS
  Twenty-four per cent of patients undergoing tonsillectomy had positive cultures from their tonsils pre-operatively. Patients with bacterial colonisation of the tonsillar fossa pre-operatively had an increased rate of post-tonsillectomy haemorrhage (odds ratio: 3.8, 1.1-12.1, 95 per cent confidence intervals, p = 0.04).
  
  
  CONCLUSIONS
  This prospective study has found a relationship between bacterial colonisation of the tonsillar fossa and post-tonsillectomy haemorrhage. This suggests that there may be an argument for the use of antibiotics in those cases with positive pre-operative cultures. In view of the types of pathogens isolated, we feel that the management of a post-tonsillectomy bleed should include a beta lactamase inhibiting antibiotic.
authors: Department of ENT, Charing Cross Hospital, London, UK. jstephens@doctors.org.uk
authors: J C
authors: JC
authors: Stephens
authors: C
authors: C
authors: Georgalas
authors: M
authors: M
authors: Kyi
authors: K
authors: K
authors: Ghufoor
mesh_terms: D000293:Adolescent; D000328:Adult; D001419:Bacteria / Q000145:classification / Q000302:isolation & purification; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008297:Male; D014066:Palatine Tonsil / Q000382:microbiology*; D019106:Postoperative Hemorrhage / Q000209:etiology* / Q000382:microbiology; D011184:Postoperative Period; D011446:Prospective Studies; D012307:Risk Factors; D014068:Tonsillectomy / Q000009:adverse effects*