[Advances in cardiovascular system endocrine].
Bioactive substances secreted from various cells of heart and vessels play a very important role in functional homeostasis of cardiovascular system. Discoveries of new bioactive peptides not only boost the cognition of the diseases, but also have extensive clinically prospectives in preventing and treating cardiovascular diseases. Bioactive peptides secreted from cardiovascular system have both multiple forms and diverse functions. The functional complexities of peptides correlated with receptor, distribution and expression of receptor subtype, and splicing of gene. In additon, the multifunctions of peptides are concerned with other fragments of the same peptide precursor, and with the choices of the same ligend for multiple receptors.
Tang
Chao-Shu
CS
Department of Physiology and Pathophysiology, Peking University Health Science Center, Beijing 100083, China.
Qi
Yong-Fen
YF
D000818:Animals; D001685:Biological Factors / Q000378:metabolism; D002320:Cardiovascular Physiological Phenomena; D002319:Cardiovascular System / Q000378:metabolism*; D006801:Humans; D036341:Intercellular Signaling Peptides and Proteins / Q000502:physiology*; D036361:Peptide Hormones / Q000378:metabolism / Q000502:physiology*; D018000:Receptors, Peptide / Q000502:physiology*
D001685:Biological Factors; D036341:Intercellular Signaling Peptides and Proteins; D036361:Peptide Hormones; D018000:Receptors, Peptide