Studies directed to understanding the structure of chitosan-metal complexes: investigations of mono- and disaccharide models with platinum(II) group metals.
X-ray and NMR experiments were performed with simple chitosan models based on glucosamine monosaccharides and disaccharides to understand the binding properties and structures of the complexes formed between this polysaccharide and platinum(II) metals. Subjection of the glucosamine derivatives with [PdCl2(PhCN)2] provided trans-diamine complexes which upon further treatment with excess (NH4)PF6 generated complexes possessing two 5-membered chelate rings involving the C2-amine and the C3-hydroxyl group of the two individual glucosamine units.
Johannesen
Sine A
SA
Department of Chemistry and Interdisciplinary Nanoscience Center, University of Aarhus, Langelandsgade 140, 8000 Aarhus C, Denmark.
Petersen
Bent O
BO
Duus
Jens O
JO
Skrydstrup
Troels
T
D002240:Carbohydrate Sequence; D048271:Chitosan / Q000737:chemistry*; D018360:Crystallography, X-Ray; D004187:Disaccharides / Q000138:chemical synthesis* / Q000737:chemistry*; D007202:Indicators and Reagents; D009682:Magnetic Resonance Spectroscopy; D008670:Metals / Q000737:chemistry*; D008969:Molecular Sequence Data; D009005:Monosaccharides / Q000138:chemical synthesis* / Q000737:chemistry*; D009844:Oligosaccharides / Q000138:chemical synthesis / Q000737:chemistry; D017671:Platinum Compounds / Q000138:chemical synthesis* / Q000737:chemistry*
D004187:Disaccharides; D007202:Indicators and Reagents; D008670:Metals; D009005:Monosaccharides; D009844:Oligosaccharides; D017671:Platinum Compounds; D048271:Chitosan