Microwave assisted medicinal chemistry.
Microwave irradiation has been used to enhance organic reactions since the mid 80's, its use within the field of medicinal chemistry is not so widely evident in the literature. The present review highlights the use of microwave chemistry as an important tool for the fast development of structure activity relationship in several programs related to various therapeutic areas.
Alcázar
Jesús
J
Johnson and Johnson Pharmaceutical Research and Development, Division of Janssen-Cilag, S.A. Jarama s/n. 45007 Toledo, Spain. jalcazar@prdes.jnj.com
Diels
Gaston
G
Schoentjes
Bruno
B
D002626:Chemistry, Pharmaceutical; D008872:Microwaves; D004364:Pharmaceutical Preparations / Q000145:classification; D013329:Structure-Activity Relationship
D004364:Pharmaceutical Preparations