title: Leg bone pain syndrome in a patient with ulcerative colitis treated with cyclosporin.
abstract: BACKGROUND
  Leg bone pain syndrome is an unusual condition associated with the use of calcineurin antagonists, initially described in patients receiving allograft transplantation.
  
  
  OBJECTIVE
  To describe the first known reported case of leg bone pain syndrome in a patient with ulcerative colitis receiving cyclosporin.
  
  
  RESULTS
  Investigations revealed no diagnostic features. Calcium channel blocker was used successfully in the treatment of this condition.
  
  
  CONCLUSIONS
  In the absence of diagnostic investigations, a high index of clinical suspicion is needed to diagnose and successfully manage leg bone pain syndrome. This may prevent further complications such as osteonecrosis that may arise.
authors: Department of Gastroenterology, Beaumont Hospital, Beaumont, Dublin, Ireland. hizwani@yahoo.co.uk
authors: A H Abdul
authors: AH
authors: Rahman
authors: C
authors: C
authors: O'Brien
authors: S E
authors: SE
authors: Patchett
mesh_terms: D000328:Adult; D002121:Calcium Channel Blockers / Q000627:therapeutic use; D003093:Colitis, Ulcerative / Q000188:drug therapy*; D016572:Cyclosporine / Q000009:adverse effects*; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects*; D007867:Leg Bones; D009543:Nifedipine / Q000627:therapeutic use; D010146:Pain / Q000139:chemically induced* / Q000188:drug therapy; D011247:Pregnancy; D011248:Pregnancy Complications / Q000188:drug therapy*; D013577:Syndrome
chemical_list: D002121:Calcium Channel Blockers; D007166:Immunosuppressive Agents; D016572:Cyclosporine; D009543:Nifedipine