title: Interventions to reduce harm associated with adolescent substance use.
abstract: A major proportion of the disease burden and deaths for young people in developed nations is attributable to misuse of alcohol and illicit drugs. Patterns of substance use established in adolescence are quite stable and predict chronic patterns of use, mortality, and morbidity later in life. We integrated findings of systematic reviews to summarise evidence for interventions aimed at prevention and reduction of harms related to adolescent substance use. Evidence of efficacy was available for developmental prevention interventions that aim to prevent onset of harmful patterns in settings such as vulnerable families, schools, and communities, and universal strategies to reduce attractiveness of substance use. Regulatory interventions aim to increase perceived costs and reduce availability and accessibility of substances. Increasing price, restricting settings of use, and raising legal purchase age are effective in reducing use of alcohol and tobacco and related harms. Screening and brief intervention are efficacious, but efficacy of a range of treatment approaches has not been reliably established. Harm-reduction interventions are effective in young people involved in risky and injecting substance use.
authors: Centre for Adolescent Health, Murdoch Childrens Research Institute and School of Psychology, Deakin University, Victoria, Australia.
authors: J W
authors: JW
authors: Toumbourou
authors: Centre for Addictions Research of British Colombia, University of Victoria, PO Box 1700 STN CSC Victoria, BC V8W 2Y2, Canada; National Drug Research Institute, Curtin University, Perth, Australia. Electronic address: timstock@uvic.ca.
authors: T
authors: T
authors: Stockwell
authors: Department of Psychiatry and Behavioral Sciences, School of Medicine, University of Washington, Seattle, USA.
authors: C
authors: C
authors: Neighbors
authors: Department of Psychiatry and Behavioral Sciences, School of Medicine, University of Washington, Seattle, USA.
authors: G A
authors: GA
authors: Marlatt
authors: Centre for Addictions Research of British Colombia, University of Victoria, PO Box 1700 STN CSC Victoria, BC V8W 2Y2, Canada.
authors: J
authors: J
authors: Sturge
authors: Centre for Addictions and Mental Health, Toronto, Ontario, Canada.
authors: J
authors: J
authors: Rehm
mesh_terms: D000293:Adolescent; D000294:Adolescent Behavior; D000328:Adult; D001521:Behavior Therapy; D019049:Developed Countries; D003906:Developing Countries; D005260:Female; D006801:Humans; D008297:Male; D012307:Risk Factors; D019966:Substance-Related Disorders / Q000453:epidemiology / Q000401:mortality / Q000517:prevention & control