title: Comparison of salivary fluoride levels following use of dentifrices containing different concentrations of fluoride.
abstract: Many industrialized countries have reported a decline in caries prevalence over the past few decades. These reductions have been related to the regular use of fluoride dentifrices. Fluoride dentifrices are the most cost-effective and efficient means of caries prevention. However, there have been concerns regarding the risk of fluorosis in children due to the ingestion of dentifrices. This has led to the use of dentifrices with low concentration of fluoride. Salivary fluoride levels after tooth-brushing have been shown to be related to the anticaries efficacy of fluoride dentifrices. The present study was designed to evaluate the effect of the concentration of fluoride in the dentifrice, on the salivary fluoride level in children. Twenty children in the age group of five to six years were randomly selected and divided into two groups using, either 500ppm or 1000ppm fluoride dentifrice (sodium monofluorophosphate). Salivary fluoride levels at 0, 15, 30, 45, 60, minutes after brushing were estimated. The data collected was statistically evaluated using the unpaired t-test. The results showed that salivary fluoride levels following use of 500ppm fluoride dentifrice were significantly lower than 1000ppm fluoride dentifrice. The low salivary fluoride levels may thereby reduce the anticaries efficacy. Hence, the pros and cons of recommending a low fluoride concentration dentifrice must be judiciously considered.
authors: Department of Pediatric and Preventive Dentistry, Nair Hospital Dental College, Mumbai, India.
authors: D I
authors: DI
authors: Nagpal
authors: S G
authors: SG
authors: Damle
mesh_terms: D002327:Cariostatic Agents / Q000008:administration & dosage* / Q000009:adverse effects / Q000032:analysis; D002648:Child; D002675:Child, Preschool; D003731:Dental Caries / Q000517:prevention & control; D003802:Dentifrices / Q000008:administration & dosage / Q000009:adverse effects / Q000737:chemistry*; D005260:Female; D005459:Fluorides / Q000008:administration & dosage* / Q000009:adverse effects / Q000032:analysis; D009050:Fluorosis, Dental / Q000209:etiology / Q000517:prevention & control; D006801:Humans; D008297:Male; D012463:Saliva / Q000737:chemistry*
chemical_list: D002327:Cariostatic Agents; D003802:Dentifrices; D005459:Fluorides