Use of clopidogrel in coronary artery disease.
Clopidogrel has an established and important role in the management of patients with coronary artery disease after an acute event. It is generally a well-tolerated drug. The major common problem associated with its use is the increased incidence of bleeding complications during or after coronary artery bypass graft surgery when clopidogrel is used within five days before surgery. For this reason, it is recommended to stop clopidogrel at least five days, and preferably one week before surgery.
Sureddi
Ravi K
RK
Department of Medicine, Central Arkansas Veterans Healthcare System, University of Arkansas for Medical Sciences, USA.
D000077144:Clopidogrel; D003327:Coronary Disease / Q000188:drug therapy* / Q000503:physiopathology; D004562:Electrocardiography / Q000187:drug effects; D006801:Humans; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use*; D013988:Ticlopidine / Q000031:analogs & derivatives* / Q000627:therapeutic use; D016896:Treatment Outcome
D010975:Platelet Aggregation Inhibitors; D000077144:Clopidogrel; D013988:Ticlopidine