title: Acute otitis media in schoolchildren: allergic diseases and skin prick test positivity.
abstract: CONCLUSIONS
  Single and repeated episodes of acute otitis media (AOM) in 10-year-old children were associated with reported allergic disease. Further, skin prick test (SPT)-negative children with reported asthma and allergic rhinoconjunctivitis had increased risk of AOM. We suggest that optimal treatment of allergic symptoms may have an effect on AOM in school children.
  
  
  OBJECTIVE
  The objective of the study was to estimate associations between AOM, allergic diseases and SPT positivity in 10-year-old children.
  
  
  METHODS
  Population-based cross-sectional study of 3406 10-year-old children living in Oslo. Main outcome measures were questionnaire-based information on AOM and reported physician-diagnosed allergic diseases with symptoms during the last year. In addition, 2657 children were skin prick tested. Logistic regression analyses were performed to estimate associations and control for potential confounders.
  
  
  RESULTS
  One or more episodes of AOM were present in 13.8% (n=470) of the children; 9.7% (n=331) had single episodes, while 4.1% (n=139) had two or more infections. We found a statistically significant association between AOM and reported allergic diseases, strongest for AOM and asthma with odds ratio 2.7 (95% confidence interval 1.8-4.0) and 2.3 (95% confidence interval 1.3-4.3) for single and two or more episodes of AOM, respectively. The risk for AOM was increased in asthmatic SPT-negative children compared with asthmatic SPT-positive children, the odds ratios were 3.0 (1.7-5.4) and 1.5 (0.8-2.8), respectively. The same tendency was found for allergic rhinoconjunctivitis.
authors: Department of Otorhinolaryngology, Faculty Division of Akershus University Hospital, University of Oslo, Sykehusvagen 27, 1478 Lørenskog, Norway. y.e.bentdal@medisin.uio.no
authors: Yngvild E
authors: YE
authors: Bentdal
authors: Per
authors: P
authors: Nafstad
authors: Gunnhild
authors: G
authors: Karevold
authors: Kari J
authors: KJ
authors: Kvaerner
mesh_terms: D000208:Acute Disease; D001249:Asthma / Q000175:diagnosis / Q000453:epidemiology; D002648:Child; D015897:Comorbidity; D003233:Conjunctivitis, Allergic / Q000175:diagnosis / Q000453:epidemiology; D003430:Cross-Sectional Studies; D003876:Dermatitis, Atopic / Q000175:diagnosis / Q000453:epidemiology; D005260:Female; D006801:Humans; D006967:Hypersensitivity / Q000175:diagnosis / Q000453:epidemiology*; D007428:Intradermal Tests; D008297:Male; D008403:Mass Screening; D010033:Otitis Media / Q000175:diagnosis / Q000453:epidemiology*; D012008:Recurrence; D012141:Respiratory Tract Infections / Q000175:diagnosis / Q000453:epidemiology; D013223:Statistics as Topic; D011795:Surveys and Questionnaires