title: Age has no effect on de novo constitutional t(11;22) translocation frequency in sperm.
abstract: We analyzed de novo constitutional t(11;22) translocation frequency in sperm derived from normal healthy males as a function of the age of the sperm donors (from 25 to 51). Translocation-specific polymerase chain reaction demonstrated no age-dependent increment in the frequency of the rearrangements.
authors: Division of Molecular Genetics, Institute for Comprehensive Medical Science, Fujita Health University, Toyoake, Japan.
authors: Takema
authors: T
authors: Kato
authors: Kouji
authors: K
authors: Yamada
authors: Hidehito
authors: H
authors: Inagaki
authors: Hiroshi
authors: H
authors: Kogo
authors: Tamae
authors: T
authors: Ohye
authors: Beverly S
authors: BS
authors: Emanuel
authors: Hiroki
authors: H
authors: Kurahashi
mesh_terms: D000328:Adult; D000375:Aging / Q000235:genetics*; D006801:Humans; D008297:Male; D008875:Middle Aged; D013094:Spermatozoa / Q000502:physiology*; D014178:Translocation, Genetic / Q000235:genetics*