title: Polymorphism of heart fatty acid-binding protein gene associatied with fatness traits in the chicken.
abstract: Fatty acid-binding proteins (FABP) belong to a superfamily of lipid binding proteins that exhibit a high affinity for long chain fatty acids and appear to function in metabolism and intracellular transportation of lipids. The current study was designed to investigate the effects of heart (H)-FABP gene on chicken growth and body composition traits. The Northeast Agricultural University divergent broiler lines for abdominal fat and a broiler X silkie F2 population were used in this study. Body weight and body composition traits were measured in the populations. Primers were designed according to the chicken H-FABP gene sequence. Polymorphisms between parental lines were detected by DNA sequencing. PCR-RFLP and PCR-fragment length polymorphism methods were developed to genotype the populations. The results showed that the H-FABP gene polymorphisms in the two populations were associated with abdominal fat percentage. It implied that H-FABP gene can be a candidate locus or linked to a major gene(s) that affects abdominal fat content in the chicken.
authors: College of Animal Science and Technology, Northeast Agricultural University, Harbin, China.
authors: Qigui
authors: Q
authors: Wang
authors: Hui
authors: H
authors: Li
authors: Li
authors: L
authors: Leng
authors: Yuxiang
authors: Y
authors: Wang
authors: Zhiquan
authors: Z
authors: Tang
authors: Ning
authors: N
authors: Li
authors: Fuchun
authors: F
authors: Zhang
mesh_terms: D000273:Adipose Tissue / Q000254:growth & development* / Q000502:physiology; D000818:Animals; D001835:Body Weight / Q000235:genetics / Q000502:physiology; D002645:Chickens / Q000235:genetics* / Q000254:growth & development*; D004247:DNA / Q000737:chemistry / Q000235:genetics; D050556:Fatty Acid-Binding Proteins / Q000235:genetics*; D005260:Female; D006239:Haplotypes / Q000235:genetics / Q000502:physiology; D016018:Least-Squares Analysis; D008297:Male; D010641:Phenotype; D016133:Polymerase Chain Reaction / Q000662:veterinary; D011110:Polymorphism, Genetic; D012150:Polymorphism, Restriction Fragment Length; D012641:Selection, Genetic
chemical_list: D050556:Fatty Acid-Binding Proteins; D004247:DNA