Infection with Echinococcus granulosus (Batsch, 1786) and expression of superoxide dismutase gene at mRNA level in hepatocytes.
Superoxide dismutase (SOD) plays an important role in detoxication of the organism. Its function is to protect the organism against the cytotoxic action of free radicals. The highest expression of superoxide dismutase was observed in the hepatocytes adjacent to the hydatid cyst. The expression of this gene in the hepatocytes of infected livers 5 cm apart from the infection site was slightly lower.
Kozłowska-Łój
Jolanta
J
Chair and Department of Biology and Genetics, Skubiszewski Medical University of Lublin, Staszica 6, 20-081 Lublin, Poland.
Rzymowska
Jolanta
J
D000818:Animals; D004443:Echinococcosis / Q000201:enzymology*; D048209:Echinococcus granulosus / Q000502:physiology; D015870:Gene Expression; D005786:Gene Expression Regulation; D022781:Hepatocytes / Q000201:enzymology*; D006801:Humans; D017403:In Situ Hybridization; D012333:RNA, Messenger / Q000096:biosynthesis; D017382:Reactive Oxygen Species / Q000378:metabolism; D013482:Superoxide Dismutase / Q000235:genetics*
D012333:RNA, Messenger; D017382:Reactive Oxygen Species; D013482:Superoxide Dismutase