A case of thyroid hormone resistance: Prospective follow-up during pregnancy and obstetric outcome.
We describe the case of a patient with resistance to thyroid hormone (R243W substitution) and her obstetric outcome. The patient gave birth to a healthy girl, unaffected by the R243W mutation. Two years later, following an uneventful pregnancy, a baby boy was born at term; he presented the same thyroid hormone receptor mutation as his mother. Follow-up of gestational thyroid hormone levels is reported during both pregnancies and related to obstetric outcome.
Massaad
Dany
D
Academic Hospital, Free University of Brussels, 101 Laarbeeklaan, 1090 Jette, Belgium.
Poppe
Kris
K
Lissens
Willy
W
Velkeniers
Brigitte
B