title: Topical tacrolimus is effective against eczema in Wiskott-Aldrich syndrome (WAS).
abstract: The Wiskott-Aldrich syndrome is a rare X-linked immunodeficiency characterized by microplatelet thrombocytopenia and eczema. Eczema may be severe and facilitate entry of microorganism into the host.
  
  
  CONCLUSIONS
  We report for the first time that eczema in infants with WAS can be effectively treated with topical ttacrolimus.
authors: Department of Pediatric Oncology, Haematology and immunology, Children's Hospital, UKD, Heinrich Heine University, Moorenstr. 5, 40225 Düsseldorf, Germany.
authors: Klaus
authors: K
authors: Bienemann
authors: Sonja
authors: S
authors: Gudowius
authors: Tim
authors: T
authors: Niehues
mesh_terms: D000279:Administration, Cutaneous; D004485:Eczema / Q000188:drug therapy* / Q000235:genetics* / Q000473:pathology; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage*; D007223:Infant; D008297:Male; D016559:Tacrolimus / Q000008:administration & dosage*; D016896:Treatment Outcome; D014923:Wiskott-Aldrich Syndrome / Q000150:complications*
chemical_list: D007166:Immunosuppressive Agents; D016559:Tacrolimus