Total synthesis of the potent antitumor macrolides pladienolide B and D.
Kanada
Regina M
RM
Discovery Research Laboratories II, Eisai Co., Ltd. 5-1-3 Tokodai, Tsukuba, Ibaraki, 300-2635, Japan.
Itoh
Daisuke
D
Nagai
Mitsuo
M
Niijima
Jun
J
Asai
Naoki
N
Mizui
Yoshiharu
Y
Abe
Shinya
S
Kotake
Yoshihiko
Y
D000903:Antibiotics, Antineoplastic / Q000138:chemical synthesis* / Q000737:chemistry; D004852:Epoxy Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D018942:Macrolides / Q000138:chemical synthesis* / Q000737:chemistry; D008968:Molecular Conformation; D013237:Stereoisomerism
D000903:Antibiotics, Antineoplastic; D004852:Epoxy Compounds; D018942:Macrolides; C522342:pladienolide B; C522343:pladienolide D