title: Cadaveric renal transplantation: our experience at the Institute of Kidney Diseases & Research Centre, Institute of Transplantation Sciences, Ahmedabad.
abstract: In a developing country such as India, cadaveric renal transplantation accounts for only less than 1% of total renal transplantations. The reasons for such a low rate of cadaveric transplantation are many, ranging from lack of awareness to socioeconomic reasons. Our institute conducted a statewide public awareness program and initiated an intercity organ harvesting program. This doubled the cadaveric renal transplantations in the last 2 years. We performed 38 cadaveric transplantations among 190 renal transplantations in the last year (August 2005 to July 2006). We retrieved kidneys from 21 donors, of whom 9 were outside our city. From 21 donors we transplanted 38 recipients; out of whom 3 received dual kidneys and one kidney was discarded. The Mean age of the donors was 41.4 +/- 18.2 years with a mean cold ischemia time of 6.9 +/- 3.8 hours. Sixty-eight percent had delayed graft function. At the last follow-up, which was 190 +/- 98 days, patient survival rate was 90%: 4 patients died, including 2 due to bacterial sepsis and 2 due to cytomegalovirus (CMV) disease. The Graft survival rate was 85%, and the death-censored graft survival rate was 90%. Mean serum creatinine value at the last follow-up was 1.2 +/- 0.3 mg%. There were 5 episodes of acute rejection in 31 patients during first 3 months (16% acute rejection rate). The increase in cadaveric transplantations was associated with satisfactory patient and graft survival despite the high incidence of delayed graft function.
authors: Department of Nephrology and Transplantation Medicine, Dr H L Trivedi Institute Of Transplantation Sciences, Ahmedabad, Gujarat, India. ikdrcad1@sancharnet.in
authors: A
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authors: Feroz
authors: M
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authors: Dabhi
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authors: M
authors: Gumber
authors: S
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authors: Gupta
authors: P R
authors: PR
authors: Shah
authors: S J
authors: SJ
authors: Rizvi
authors: P R
authors: PR
authors: Modi
authors: S A
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authors: Shah
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authors: Khemchandani
authors: N S
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authors: Bhandari
authors: G P
authors: GP
authors: Bhosale
authors: V R
authors: VR
authors: Shah
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authors: VB
authors: Trivedi
authors: A P
authors: AP
authors: Dave
authors: J M
authors: JM
authors: Dave
authors: H L
authors: HL
authors: Trivedi
mesh_terms: D000328:Adult; D002102:Cadaver; D003906:Developing Countries; D006801:Humans; D007194:India; D016030:Kidney Transplantation / Q000706:statistics & numerical data*; D008875:Middle Aged; D014019:Tissue Donors; D020858:Tissue and Organ Harvesting / Q000379:methods