Urinary tract infections revisited.
Urinary tract infections (UTIs) remain a significant clinical problem, despite antibiotic treatment and surgical correction of reflux and malformations. Here we propose that novel molecular tools may be applied to modernize and individualize the diagnosis and therapy of UTI. Determinants of bacterial virulence and host resistance are relatively well understood at the molecular level, and technology for their detection is within reach.
Godaly
G
G
Institute of Laboratory Medicine, Department of Microbiology, Immunology and Glycobiology, Lund University, Lund, Sweden.
Svanborg
C
C
D004926:Escherichia coli / Q000472:pathogenicity*; D004927:Escherichia coli Infections / Q000175:diagnosis / Q000382:microbiology* / Q000628:therapy; D006801:Humans; D014552:Urinary Tract Infections / Q000175:diagnosis / Q000382:microbiology* / Q000628:therapy; D014774:Virulence