Information integration of protein-protein interactions as essential tools for immunomics.
After a brief introduction to point out the necessity to advance for a global understanding of the macromolecular interactions occurring during the immune system development and responses, Section 2 will be devoted to analyse the current tools for an automatic location of information on these protein-protein interactions in the web. In the next section (Section 3), we will point out different action lines to improve these tools and, consequently, to increase the efficiency to establish (to understand) the "protein network skeleton" that controls our immune responses. Finally, we will briefly present our current strategy and work to advance towards this goal.
Montañez
Raúl
R
Department of Molecular Biology and Biochemistry, Centre for Biomedical Research on Rare Diseases, University of Malaga, E-29071 Malaga, Spain.
Navas-Delgado
Ismael
I
Medina
Miguel Angel
MA
Aldana-Montes
José F
JF
Sánchez-Jiménez
Francisca
F
D019295:Computational Biology; D019992:Databases as Topic; D007107:Immune System / Q000276:immunology / Q000502:physiology*; D025941:Protein Interaction Mapping; D049490:Systems Biology / Q000379:methods*