Too much of a good thing, is it bad? Adrenaline on trial.
Adrenaline is vital in the treatment of severe allergic reactions (anaphylaxis), however it is often underutilised or inappropriately administered. Adrenaline treatment is not without risk and most adverse reactions to adrenaline occur when it is given in overdose or as an intravenous bolus. We report a case of myocardial injury and hypotension following inappropriate administration of adrenaline.
Sood
Jai-deep
JD
Auckland City Hospital, Auckland.
Empson
Marianne
M
Fitzharris
Penny
P
Stewart
Jim
J
D000082:Acetaminophen / Q000009:adverse effects; D000328:Adult; D000799:Angioedema / Q000139:chemically induced / Q000188:drug therapy; D001145:Arrhythmias, Cardiac / Q000139:chemically induced / Q000175:diagnosis / Q000628:therapy; D004305:Dose-Response Relationship, Drug; D004338:Drug Combinations; D004342:Drug Hypersensitivity / Q000188:drug therapy*; D004837:Epinephrine / Q000008:administration & dosage / Q000009:adverse effects*; D006801:Humans; D007275:Injections, Intravenous; D007279:Injections, Subcutaneous; D008297:Male; D008508:Medication Errors; D008787:Metoclopramide / Q000009:adverse effects; D011654:Pulmonary Edema / Q000139:chemically induced / Q000175:diagnosis / Q000628:therapy; D014060:Tongue Diseases / Q000139:chemically induced / Q000188:drug therapy; D016896:Treatment Outcome; D018487:Ventricular Dysfunction, Left / Q000139:chemically induced / Q000175:diagnosis / Q000628:therapy
D004338:Drug Combinations; D000082:Acetaminophen; C036504:Paramax; D008787:Metoclopramide; D004837:Epinephrine