[Cotrimoxazole Pneumocystis jiroveci pneumonia treatment failure: co-infection cytomegalovirus role?].
Pneumocystis jiroveci pneumonia is a classic opportunist infection affecting AIDS patients. However it is less frequent since systematic prophylaxis and antiretroviral therapies. Treatment resistance is rare in France. We report the case of a severe Pneumocystis jiroveci pneumonia with treatment resistance to standard treatment and fatal outcome. The different causes of treatment resistance, notably the role of CMV co-infection, were reviewed and discussed.
Scemama
J
J
Service d'anesthésie et de réanimation, CHU Jean-Verdier, APHP, Bondy, France.
Amathieu
R
R
Tual
L
L
Fessenmeyer
C
C
Stirnemann
J
J
Dhonneur
G
G
D000890:Anti-Infective Agents / Q000494:pharmacology*; D003586:Cytomegalovirus Infections / Q000150:complications*; D024881:Drug Resistance, Bacterial; D017809:Fatal Outcome; D006801:Humans; D008297:Male; D008875:Middle Aged; D045363:Pneumocystis carinii; D011020:Pneumonia, Pneumocystis / Q000188:drug therapy* / Q000821:virology*; D015662:Trimethoprim, Sulfamethoxazole Drug Combination / Q000494:pharmacology*
D000890:Anti-Infective Agents; D015662:Trimethoprim, Sulfamethoxazole Drug Combination