Angioplasty for non-arteriosclerotic renal artery stenosis: the efficacy of cutting balloon angioplasty versus conventional angioplasty.
OBJECTIVE
We examined the efficacy of conventional balloon angioplasty and cutting balloon angioplasty (CBA) for the treatment of non-arteriosclerotic renal artery stenosis (RAS).


METHODS
From 1993 to 2005, 20 patients underwent 27 percutaneous transluminal renalangioplasty (PTRA) for non-arteriosclerotic RAS (men: 8, women: 12, 25.5 +/- 2 years old; 16 fibromuscular dysplasia (FMD), 4 Takayasu disease). We evaluated the efficacy of CBA by comparing the rate of initial technical success and surgical conversion.


RESULTS
Before the clinical authorization of CBA, three of twelve patients (25 %) underwent surgical bypass due to the failure of PTRA due to the hardness of the lesion. After the approval of cutting balloon, we performed CBA in four cases (2 FMD,2 Takayasu disease) to dilate hard lesions, within which a properly sized balloon could not dilate due to their hardness, or to reduce the risk of local dissection. Initial successes were obtained in all patients (8/8, 100%) and none of the patients underwent surgical conversion. Despite of the good initial result, restenosis was observed in three cases within 6 month (3/4, 75%). Additional interventions were performed in all patients, then, the severity of the restenotic lesion was found not to be exceeded comparing with the initial lesion.


CONCLUSIONS
The cutting balloon angioplasty may be safe and useful procedure for hard lesions of RAS caused by non-arteriosclerotic disease? especially fibromuscular dysplasia. The cutting balloon may provide the initial success, but the effect on long-term patency is still controversial.
Tanaka
Ryoichi
R
Department of Radiology, Iwate Medical University, 19-1 Uchimaru Morioka, Iwate, Japan. rtanaka@iwate-med.ac.jp
Higashi
Masahiro
M
Naito
Hiroaki
H
D000293:Adolescent; D000328:Adult; D000792:Angiography; D000800:Angioplasty, Balloon / Q000295:instrumentation*; D004867:Equipment Design; D005260:Female; D005352:Fibromuscular Dysplasia / Q000175:diagnosis / Q000628:therapy*; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D012008:Recurrence; D012078:Renal Artery Obstruction / Q000175:diagnosis / Q000628:therapy*; D019233:Retreatment; D015607:Stents; D013625:Takayasu Arteritis / Q000175:diagnosis / Q000628:therapy*; D016896:Treatment Outcome; D018608:Ultrasonography, Doppler