title: Diabetic myonecrosis in an orthotopic heart transplant recipient.
abstract: Diabetic myonecrosis or muscle infarction (DMI) is a rare cause of lower extremity pain that usually occurs in patients with poorly controlled diabetes. Although most patients recover with opiate analgesics and anti-inflammatory medications, this type of myonecrosis is associated with the presence of serious vascular disease. Consideration of this diagnosis and use of soft-tissue imaging are especially important in diabetic organ transplant recipients to prevent erroneous treatment for presumed infection. We describe what we believe is the first reported case of diabetic myonecrosis occurring in a patient with iatrogenically induced diabetes after orthotopic heart transplantation.
authors: Department of Medicine, Health Sciences Center, University of Florida College of Medicine, Gainesville, Florida 32610-0277, USA.
authors: Joanne A
authors: JA
authors: Byars
authors: Eric I
authors: EI
authors: Rosenberg
mesh_terms: D000328:Adult; D001707:Biopsy, Needle; D048909:Diabetes Complications / Q000139:chemically induced* / Q000473:pathology; D003924:Diabetes Mellitus, Type 2 / Q000139:chemically induced* / Q000503:physiopathology; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D004359:Drug Therapy, Combination; D005260:Female; D005500:Follow-Up Studies; D016027:Heart Transplantation / Q000276:immunology / Q000379:methods*; D006801:Humans; D007150:Immunohistochemistry; D007166:Immunosuppressive Agents / Q000009:adverse effects* / Q000627:therapeutic use; D018482:Muscle, Skeletal / Q000473:pathology*; D009336:Necrosis / Q000139:chemically induced / Q000473:pathology; D011241:Prednisone / Q000009:adverse effects* / Q000627:therapeutic use; D018570:Risk Assessment; D014184:Transplantation, Homologous
chemical_list: D007166:Immunosuppressive Agents; D011241:Prednisone