title: Effects of four rice herbicides on some metabolic and toxicology parameters of teleost fish (Leporinus obtusidens).
abstract: Effects of different herbicides on acetylcholinesterase (AChE), catalase and TBARS formation in teleost fish (Leporinus obtusidens) were studied. Fish were exposed during 30 days at concentrations of herbicides used in rice field. AChE activity in the brain decreased significantly after exposure to the herbicides clomazone and quinclorac. However, AChE activity increased significantly in muscle tissue after exposure to clomazone, propanil and metsulfuron methyl. Fish exposed to quinclorac, propanil and metsulfuron methyl showed TBARS decreased levels in brain and muscle tissues. However, TBARS and catalase activity increased in liver tissue after clomazone and propanil exposure. This study pointed out long-term effects on AChE activity, oxidative stress and antioxidant enzyme catalase in tissues of L. obtusidens after exposure to environmentally relevant concentrations of rice field herbicides. These parameters have been used to monitor fish toxicity in rice field system.
authors: Departamento de Química - Laboratório de Bioquímica Adaptativa, Universidade Federal de Santa Maria (UFSM), 97105-900 Santa Maria, RS, Brazil.
authors: Bibiana Silveira
authors: BS
authors: Moraes
authors: Vania Lúcia
authors: VL
authors: Loro
authors: Lissandra
authors: L
authors: Glusczak
authors: Alexandra
authors: A
authors: Pretto
authors: Charlene
authors: C
authors: Menezes
authors: Enio
authors: E
authors: Marchezan
authors: Sérgio
authors: S
authors: de Oliveira Machado
mesh_terms: D000110:Acetylcholinesterase / Q000378:metabolism; D000818:Animals; D001921:Brain / Q000187:drug effects / Q000201:enzymology / Q000378:metabolism; D002374:Catalase / Q000378:metabolism; D004305:Dose-Response Relationship, Drug; D005260:Female; D005399:Fishes / Q000378:metabolism*; D006540:Herbicides / Q000633:toxicity*; D015227:Lipid Peroxidation; D008099:Liver / Q000187:drug effects / Q000201:enzymology / Q000378:metabolism; D008297:Male; D009132:Muscles / Q000187:drug effects / Q000201:enzymology / Q000378:metabolism; D012275:Oryza / Q000254:growth & development*; D017392:Thiobarbituric Acid Reactive Substances / Q000378:metabolism; D014874:Water Pollutants, Chemical / Q000633:toxicity*
chemical_list: D006540:Herbicides; D017392:Thiobarbituric Acid Reactive Substances; D014874:Water Pollutants, Chemical; D002374:Catalase; D000110:Acetylcholinesterase