title: Pulmonary and cutaneous nocardiosis in a patient treated with corticosteroids.
abstract: Nocardiosis is a localized or disseminated infection caused by gram-positive bacteria of the genus Nocardia. The infection most commonly affects the lungs, skin and central nervous system. Nocardiosis principally occurs in individuals with cellular immunodeficiency and should be considered in the differential diagnosis when such individuals present respiratory, cutaneous or neurological alterations. Herein, we report a case of pulmonary and cutaneous nocardiosis in a patient receiving oral corticosteroids to treat bronchiolitis obliterans accompanied by organizing pneumonia of unknown origin. After long-term treatment with sulfamethoxazole-trimethoprim, the clinical and radiological profile improved.
authors: Pulmonology Department, Faculdade de Medicina, Universidade de São Paulo, SaoPaulo, Brazil. bruno.guedes2@terra.com.br
authors: Bruno Guedes
authors: BG
authors: Baldi
authors: Alfredo Nicodemos Cruz
authors: AN
authors: Santana
authors: Teresa Yae
authors: TY
authors: Takagaki
mesh_terms: D000890:Anti-Infective Agents / Q000627:therapeutic use; D001989:Bronchiolitis Obliterans / Q000188:drug therapy; D005938:Glucocorticoids / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D016867:Immunocompromised Host; D008171:Lung Diseases / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology; D008297:Male; D008875:Middle Aged; D009617:Nocardia Infections / Q000175:diagnosis* / Q000188:drug therapy / Q000276:immunology; D009616:Nocardia asteroides / Q000302:isolation & purification; D011241:Prednisone / Q000009:adverse effects* / Q000627:therapeutic use; D017192:Skin Diseases, Bacterial / Q000175:diagnosis* / Q000188:drug therapy / Q000276:immunology; D015662:Trimethoprim, Sulfamethoxazole Drug Combination / Q000627:therapeutic use
chemical_list: D000890:Anti-Infective Agents; D005938:Glucocorticoids; D015662:Trimethoprim, Sulfamethoxazole Drug Combination; D011241:Prednisone