title: Prevention of influenza episodes with colostrum compared with vaccination in healthy and high-risk cardiovascular subjects: the epidemiologic study in San Valentino.
abstract: The efficacy of a 2-month treatment with oral colostrum in the prevention of flu episodes compared with antiinfluenza vaccination was evaluated. Groups included healthy subjects without prophylaxis and those receiving both vaccination and colostrum. After 3 months of follow-up, the number of days with flu was 3 times higher in the non-colostrum subjects. The colostrum group had 13 episodes versus 14 in the colostrum + vaccination group, 41 in the group without prophylaxis, and 57 in nontreated subjects. Part 2 of the study had a similar protocol with 65 very high-risk cardiovascular subjects, all of whom had prophylaxis. The incidence of complications and hospital admission was higher in the group that received only a vaccination compared with the colostrum groups. Colostrum, both in healthy subjects and high-risk cardiovascular patients, is at least 3 times more effective than vaccination to prevent flu and is very cost-effective.
authors: San Valentino-Spoltore Vascular Screening Project, Department of Biomedical Sciences, G D'annunzio University, Chieti, Pescara, Italy.
authors: Maria Rosaria
authors: MR
authors: Cesarone
authors: Gianni
authors: G
authors: Belcaro
authors: Andrea
authors: A
authors: Di Renzo
authors: Mark
authors: M
authors: Dugall
authors: Marisa
authors: M
authors: Cacchio
authors: Irma
authors: I
authors: Ruffini
authors: Luciano
authors: L
authors: Pellegrini
authors: Gilberto
authors: G
authors: Del Boccio
authors: Filiberto
authors: F
authors: Fano
authors: Andrea
authors: A
authors: Ledda
authors: Angelica
authors: A
authors: Bottari
authors: Andrea
authors: A
authors: Ricci
authors: Stefano
authors: S
authors: Stuard
authors: Giulia
authors: G
authors: Vinciguerra
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002318:Cardiovascular Diseases / Q000453:epidemiology* / Q000276:immunology* / Q000473:pathology; D003126:Colostrum / Q000276:immunology*; D005260:Female; D006262:Health; D006801:Humans; D007108:Immune Tolerance / Q000276:immunology; D007252:Influenza Vaccines / Q000191:economics / Q000276:immunology*; D007251:Influenza, Human / Q000453:epidemiology / Q000276:immunology* / Q000473:pathology / Q000517:prevention & control*; D007558:Italy / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D012307:Risk Factors
chemical_list: D007252:Influenza Vaccines