Episodic muscle pain, stiffness, and weakness associated with tubular aggregates and myoedema.
We report a 28-year-old man who suffered from episodic muscle pain, stiffness and weakness. His serum creatine kinase (CK) levels were found to be elevated. He presented with slight proximal muscle weakness and calf hypertrophy. Muscle biopsy revealed fiber size variation and tubular aggregates (TA). Muscle magnetic resonance imaging showed areas of edema. Other muscle pathologies known to be associated with TAs or myoedema were ruled out.
Mahjneh
I
I
Department of Neurology, University of Oulu, Oulu, Finland. ibrahim.mahjneh@mhso.fi
Lamminen
A
A
Tuominen
H
H
D000328:Adult; D001706:Biopsy; D004487:Edema / Q000209:etiology*; D005387:Finland; D006801:Humans; D002479:Inclusion Bodies / Q000473:pathology; D008279:Magnetic Resonance Imaging; D008297:Male; D046529:Microscopy, Electron, Transmission; D018485:Muscle Fibers, Skeletal / Q000473:pathology; D018908:Muscle Weakness / Q000209:etiology*; D018482:Muscle, Skeletal / Q000473:pathology* / Q000503:physiopathology; D009135:Muscular Diseases / Q000473:pathology* / Q000503:physiopathology; D010146:Pain / Q000209:etiology*; D012519:Sarcoplasmic Reticulum / Q000473:pathology