Postinfectious bronchiolitis obliterans accompanied by pulmonary hemosiderosis in childhood.
In the present report, we describe an unusual presentation of post-infectious bronchiolitis obliterans accompanied by pulmonary hemosiderosis in a nine-year-old boy with persistent respiratory symptoms subsequent to an episode of acute bronchiolitis occurring at the age of seven months. After the episode, the persistent respiratory symptoms worsened significantly, and, by the age of seven, the patient began to have difficulty breathing after minimal exertion. Computed tomography of the chest presented findings consistent with bronchiolitis obliterans. Open lung biopsy revealed numerous hemosiderin-laden macrophages, as well as other findings consistent with bronchiolitis obliterans. Pulmonary hemosiderosis can occasionally be accompanied by bronchiolitis obliterans in children with severe sequelae after an episode of viral infection.
Pinto
Leonardo Araújo
LA
Department of Pediatrics, Pediatric Pulmonology Sector, Pontifícia Universidade Católica do Rio Grande doSul, Hospital São Lucas, Porto Alegre, Brazil.
Oliveira
Anick
A
Collaziol
Sintia
S
Pitrez
Paulo Márcio
PM
Jones
Marcus
M
Prolla
João Carlos
JC
Dolhnikoff
Marisa
M
Stein
Renato T
RT
D000208:Acute Disease; D000402:Airway Obstruction / Q000209:etiology* / Q000628:therapy; D001706:Biopsy; D001989:Bronchiolitis Obliterans / Q000150:complications* / Q000175:diagnosis / Q000473:pathology; D002648:Child; D006486:Hemosiderosis / Q000150:complications* / Q000175:diagnosis / Q000473:pathology; D006801:Humans; D008171:Lung Diseases / Q000150:complications / Q000175:diagnosis / Q000473:pathology; D008297:Male; D010102:Oxygen Inhalation Therapy; D012129:Respiratory Function Tests; D014057:Tomography, X-Ray Computed