Relationship between periodontal findings and Behçet's disease: a controlled study.
BACKGROUND
Behçet's disease (BD) is a chronic, relapsing, systemic vasculitis of unknown aetiology. The involvement of oral mucosal surfaces represents the onset feature of the disease in the majority of patients.


OBJECTIVE
The aim of this study was to evaluate the periodontal status of BD patients and then compare with recurrent aphthous stomatitis (RAS) patients and healthy controls. We also determined the relationship between the periodontal condition and the clinical severity of the disease in BD patients.


METHODS
Eighty-six patients with BD, 63 patients with RAS and 82 healthy subjects were included in the study. The periodontal status of all subjects was evaluated according to the community periodontal index of treatment needs (CPITN). BD patients were also assessed for clinical severity score (CSS) as described previously.


RESULTS
The mean CPITN were observed to be higher in BD patients (1.79 +/- 0.96) compared with RAS patients (1.22 +/- 0.87) and healthy controls (1.18 +/- 0.98) (p<0.001). There was a positive association between CSS and CPITN (p=0.017) in BD patients.


CONCLUSIONS
Our results showed that periodondal status is worse in BD patients and associated with disease severity. We can speculate that periodontitis may induce a systemic inflammatory process that may contribute to the development and/or progression of BD.
Akman
Ayse
A
Department of Dermatology and Venerology, Akdeniz University School of Medicine, Antalya, Turkey. aakman@akdeniz.edu.tr
Kacaroglu
Hasan
H
Donmez
Levent
L
Bacanli
Ali
A
Alpsoy
Erkan
E
D000328:Adult; D001528:Behcet Syndrome / Q000145:classification / Q000150:complications* / Q000503:physiopathology; D003731:Dental Caries / Q000150:complications; D017266:Dental Prosthesis; D005260:Female; D006801:Humans; D008297:Male; D010510:Periodontal Diseases / Q000145:classification / Q000150:complications; D010512:Periodontal Index; D012008:Recurrence; D012720:Severity of Illness Index; D013281:Stomatitis, Aphthous / Q000145:classification / Q000150:complications*; D014099:Toothbrushing