[Hypocomplementemic urticarial vasculitis syndrome. Successful therapy with intravenous immunoglobulins].
Autoimmune diseases can initially present as chronic urticaria. We describe the course of a patient with hypocomplementemic urticarial vasculitis syndrome (HUVS) as well as his successful treatment with high-dose intravenous immunoglobulins (IVIG). HUVS was diagnosed clinically and confirmed by histology and laboratory studies. After only one cycle with IVIG (2 g/kg) all HUVS symptoms were significantly decreased.
Staubach-Renz
P
P
Universitäts-Hautklinik Mainz, Langenbeckstrasse 1, 55101 Mainz, Deutschland. staubach@hautklinik.klinik.uni-mainz.de
von Stebut
E
E
Bräuninger
W
W
Maurer
M
M
Steinbrink
K
K
D000328:Adult; D000799:Angioedema / Q000175:diagnosis / Q000188:drug therapy* / Q000276:immunology / Q000473:pathology; D001327:Autoimmune Diseases / Q000175:diagnosis / Q000188:drug therapy* / Q000276:immunology / Q000473:pathology; D001706:Biopsy; D015922:Complement C1q / Q000172:deficiency*; D003176:Complement C3 / Q000172:deficiency*; D003181:Complement C4 / Q000172:deficiency*; D003937:Diagnosis, Differential; D005500:Follow-Up Studies; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000008:administration & dosage*; D007262:Infusions, Intravenous; D008180:Lupus Erythematosus, Systemic / Q000175:diagnosis / Q000188:drug therapy* / Q000276:immunology / Q000473:pathology; D008297:Male; D012867:Skin / Q000473:pathology; D018366:Vasculitis, Leukocytoclastic, Cutaneous / Q000175:diagnosis / Q000188:drug therapy* / Q000276:immunology / Q000473:pathology
D003176:Complement C3; D003181:Complement C4; D016756:Immunoglobulins, Intravenous; D015922:Complement C1q