title: Impact of local and systemic factors on the incidence of oral implant failures, up to abutment connection.
abstract: OBJECTIVE
  The aim of this retrospective study was to assess the influence of systemic and local bone and intra-oral factors on the occurrence of early implant failures, i.e. up to the abutment connection.
  
  
  METHODS
  The surgical records of 2004 consecutive patients from the total patient population who had been treated in the period 1982-2003 (with a total of 6946 Brånemark system implants) at the Department of Periodontology of the Catholic University Leuven were evaluated. For each patient the medical history was carefully checked. Data collection and analysis mainly focused on endogenous factors such as hypertension, coagulation problems, osteoporosis, hypo-hyperthyroidy, chemotherapy, diabetes type I or II, Crohn's disease, some local factors [e.g. bone quality and quantity, implant (length, diameter, location), type of edentulism, Periotest value at implant insertion, radiotherapy], smoking habits and breach of sterility during surgery.
  
  
  RESULTS
  A global failure rate of 3.6% was recorded. Osteoporosis, Crohn's disease, smoking habits, implant (length, diameter and location) and vicinity with the natural dentition were all significantly associated with early implant failures (p<0.05).
  
  
  CONCLUSIONS
  The indication for the use of oral implants should sometimes be reconsidered when alternative prosthetic treatments are available in the presence of possibly interfering systemic or local factors.
authors: Department of Periodontology, Faculty of Medicine, School of Dentistry, Oral Pathology and Maxillofacial Surgery, Catholic University of Leuven, Leuven, Belgium.
authors: Ghada
authors: G
authors: Alsaadi
authors: Marc
authors: M
authors: Quirynen
authors: Arnost
authors: A
authors: Komárek
authors: Daniel
authors: D
authors: van Steenberghe
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use; D001778:Blood Coagulation Disorders / Q000150:complications; D015519:Bone Density / Q000502:physiology; D003424:Crohn Disease / Q000150:complications; D000044:Dental Abutments; D003758:Dental Implantation, Endosseous / Q000009:adverse effects; D015921:Dental Implants / Q000706:statistics & numerical data; D017267:Dental Prosthesis Design; D019232:Dental Restoration Failure; D003922:Diabetes Mellitus, Type 1 / Q000150:complications; D003924:Diabetes Mellitus, Type 2 / Q000150:complications; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications; D006980:Hyperthyroidism / Q000150:complications; D007037:Hypothyroidism / Q000150:complications; D007575:Jaw, Edentulous / Q000145:classification; D007576:Jaw, Edentulous, Partially / Q000145:classification; D008297:Male; D016348:Osseointegration / Q000502:physiology; D010024:Osteoporosis / Q000150:complications; D011878:Radiotherapy; D012189:Retrospective Studies; D012307:Risk Factors; D012907:Smoking
chemical_list: D000970:Antineoplastic Agents; D015921:Dental Implants