Topical tacrolimus is effective against eczema in Wiskott-Aldrich syndrome (WAS).
The Wiskott-Aldrich syndrome is a rare X-linked immunodeficiency characterized by microplatelet thrombocytopenia and eczema. Eczema may be severe and facilitate entry of microorganism into the host.


CONCLUSIONS
We report for the first time that eczema in infants with WAS can be effectively treated with topical ttacrolimus.
Bienemann
Klaus
K
Department of Pediatric Oncology, Haematology and immunology, Children's Hospital, UKD, Heinrich Heine University, Moorenstr. 5, 40225 Düsseldorf, Germany.
Gudowius
Sonja
S
Niehues
Tim
T
D000279:Administration, Cutaneous; D004485:Eczema / Q000188:drug therapy* / Q000235:genetics* / Q000473:pathology; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage*; D007223:Infant; D008297:Male; D016559:Tacrolimus / Q000008:administration & dosage*; D016896:Treatment Outcome; D014923:Wiskott-Aldrich Syndrome / Q000150:complications*
D007166:Immunosuppressive Agents; D016559:Tacrolimus