title: Divided café-au-lait macule of the mouth.
abstract: We describe a 4-year-old, otherwise healthy boy with a congenital history of a perioral and labial segmental café-au-lait macule, who was noted to have unilateral localized gingival hyperpigmentation that aligned with the café-au-lait macule. This case is highly illustrative of the embryologic timing of the genetic event locally, which leads to café-au-lait type hyperpigmentation. Because the facial features and the ectoderm overlying the facial muscles develop around the third to fourth week of gestation, the distribution of this café-au-lait macule suggests development at the same time.
authors: Department of Dermatology, St Luke's-Roosevelt Hospital Center, New York, New York 10025, USA.
authors: Amanda
authors: A
authors: Sergay
authors: Nanette B
authors: NB
authors: Silverberg
mesh_terms: D019080:Cafe-au-Lait Spots / Q000151:congenital / Q000473:pathology*; D002610:Cheek / Q000473:pathology; D002675:Child, Preschool; D005881:Gingiva / Q000473:pathology; D006801:Humans; D008046:Lip / Q000473:pathology; D008297:Male; D009059:Mouth Diseases / Q000151:congenital / Q000473:pathology*