title: Effect of reading additional safety information on planned use of over-the-counter analgesics.
abstract: OBJECTIVE
  This study was used to test the effect on planned safe use of over-the-counter (OTC) analgesics of adding information about the potential for nonsteroidal anti-inflammatory drug (NSAID) interaction with antihypertensive medications, the potential for interaction of alcohol and acetaminophen, and NSAID ceiling effects to the Federal Drug Administration's (FDA's) OTC analgesics pamphlet.
  
  
  METHODS
  A randomized posttest-only double-blind experimental design was used to test an intervention with a comparison group reading the FDA pamphlet, and treatment group reading the pamphlet with added information.
  
  
  METHODS
  Participants included 137 adults.
  
  
  METHODS
  Participants read the treatment or the comparison pamphlet.
  
  
  RESULTS
  Both groups responded with similar planned use of OTC analgesics. The majority were likely to read the label before taking an OTC analgesic, but were unlikely to give acetaminophen to a family member using antihypertensive medication.
  
  
  CONCLUSIONS
  Reading additional information about OTC analgesics resulted in no greater intention to safely use analgesics. Responses indicated reluctance to use OTC analgesics, and the potential need for increased health teaching regarding use of OTC analgesics with antihypertensive medication. Public health teaching should include the importance of treating pain and selecting the safest OTC analgesics for the clinical situation.
authors: University of Connecticut School of Nursing, Storrs, Connecticut 06269-9026, USA. deborah.mcdonald@uconn.edu
authors: Deborah Dillon
authors: DD
authors: McDonald
authors: Mary Grace
authors: MG
authors: Amendola
authors: Elsa
authors: E
authors: Interlandi
authors: Karen
authors: K
authors: Wall
authors: Brent
authors: B
authors: Lewchik
authors: Lissy
authors: L
authors: Polouse
authors: Noreen
authors: N
authors: Pace
authors: Susada
authors: S
authors: Inthavong
authors: Ling
authors: L
authors: Li
mesh_terms: D000082:Acetaminophen / Q000009:adverse effects; D000328:Adult; D000428:Alcohol Drinking / Q000009:adverse effects; D000700:Analgesics / Q000009:adverse effects*; D000704:Analysis of Variance; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects; D000959:Antihypertensive Agents / Q000009:adverse effects; D001294:Attitude to Health; D016009:Chi-Square Distribution; D032882:Comprehension; D004311:Double-Blind Method; D004347:Drug Interactions; D005260:Female; D007722:Health Knowledge, Attitudes, Practice; D006801:Humans; D008297:Male; D004366:Nonprescription Drugs / Q000009:adverse effects*; D010174:Pamphlets; D010353:Patient Education as Topic / Q000379:methods*; D017751:Safety Management / Q000379:methods; D012651:Self Medication / Q000009:adverse effects / Q000379:methods / Q000523:psychology; D011795:Surveys and Questionnaires; D014481:United States; D014486:United States Food and Drug Administration
chemical_list: D000700:Analgesics; D000894:Anti-Inflammatory Agents, Non-Steroidal; D000959:Antihypertensive Agents; D004366:Nonprescription Drugs; D000082:Acetaminophen