Embolization of accessory left gastric artery to prevent acute gastric mucosal lesions in patients undergoing repeated hepatic arterial infusion chemotherapy.
OBJECTIVE
To retrospectively evaluate results of selective embolization of the accessory left gastric artery prior to repeated hepatic arterial infusion chemotherapy using a port-catheter system.


METHODS
Of 22 patients with unresectable advanced liver cancer who underwent percutaneous implantation of a port-catheter system, an accessory left gastric artery was revealed by arteriography in 16 patients before and in six patients after port-catheter implantation. The right gastric artery was embolized to prevent gastric mucosal lesions in all 22 patients. In addition, the accessory left gastric artery was selectively embolized for the same purpose using from one to six microcoils, which were from 3 to 5 mm in diameter. Within 10 days after implantation, arteriography was performed while contrast material was infused via the port.


RESULTS
Selective embolization of the accessory left gastric artery was successful in all 22 patients. No complication related to embolization of this artery occurred in any patient. A gastrointestinal mucosal lesion developed in only one case during hepatic arterial infusion chemotherapy, but was unrelated to the accessory left gastric artery.


CONCLUSIONS
Prophylactic embolization of the accessory left gastric artery is useful to avoid development of a gastrointestinal mucosal lesion resulting from hepatic arterial infusion chemotherapy.
Yamagami
T
T
Department of Radiology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan. yamagami@koto.kpu-m.ac.jp
Kato
T
T
Hirota
T
T
Yoshimatsu
R
R
Matsumoto
T
T
Nishimura
T
T
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000792:Angiography; D000970:Antineoplastic Agents / Q000008:administration & dosage* / Q000009:adverse effects; D002408:Catheters, Indwelling; D004621:Embolization, Therapeutic / Q000379:methods*; D005260:Female; D005753:Gastric Mucosa / Q000473:pathology; D006499:Hepatic Artery / Q000000981:diagnostic imaging; D006801:Humans; D007261:Infusions, Intra-Arterial; D008113:Liver Neoplasms / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D013270:Stomach / Q000098:blood supply*
D000970:Antineoplastic Agents