Localization of PcsB of Streptococcus pneumoniae and its differential expression in response to stress.
PcsB of Streptococcus pneumoniae is an essential hydrolase involved in the separation of dividing cells. In this study, it was found that PcsB localizes to the plasma membrane and is released into the growth environment, yet it is detectable on the pneumococcal surface by flow cytometry analysis. High temperature and osmolarity led to upregulation of pcsB expression.
Mills
Megumi F
MF
Department of Microbiology, University of Mississippi Medical Center, 2500 North State Street, Jackson, MS 39216, USA.
Marquart
Mary E
ME
McDaniel
Larry S
LS
D001426:Bacterial Proteins / Q000096:biosynthesis / Q000378:metabolism*; D018797:Cell Cycle Proteins / Q000096:biosynthesis / Q000378:metabolism*; D002462:Cell Membrane / Q000737:chemistry; D005434:Flow Cytometry; D015964:Gene Expression Regulation, Bacterial; D006358:Hot Temperature; D006867:Hydrolases / Q000096:biosynthesis* / Q000378:metabolism* / Q000502:physiology; D008565:Membrane Proteins / Q000096:biosynthesis* / Q000378:metabolism*; D009997:Osmotic Pressure; D013296:Streptococcus pneumoniae / Q000378:metabolism*; D015854:Up-Regulation
D001426:Bacterial Proteins; D018797:Cell Cycle Proteins; D008565:Membrane Proteins; D006867:Hydrolases