title: Ventricular tachycardia in non-compaction of left ventricle: is this a frequent complication?
abstract: BACKGROUND
  Isolated left ventricular non-compaction is the result of incomplete myocardial morphogenesis, leading to persistence of the embryonic myocardium. The condition is recognized by an excessively prominent trabecular meshwork and deep intertrabecular recesses of the left ventricle. Whether these intertrabecular recesses are a favorable substrate for ventricular arrhythmias is unclear. Some reports have found that the fatal ventricular arrhythmias may occur in approximately half of the patients. In this report we investigated about this association.
  
  
  RESULTS
  In total we evaluated a continuous series of 238 patients affected by non-compaction. Periodic Holter monitoring was performed every 6 months for 4 years. Only 11 patients had documented ventricular tachycardia, which was sustained in two cases and non-sustained in nine. In no cases we observed ventricular fibrillation.
  
  
  CONCLUSIONS
  Non-compaction alone does not seem to be a risk factor for malignant ventricular arrhythmias.
authors: Division of Cardiology, Casa del Sole Hospital, Palermo, Italy. Giovanni.fazio-aaaa@poste.it
authors: Giovanni
authors: G
authors: Fazio
authors: Giovanni
authors: G
authors: Corrado
authors: Elisabetta
authors: E
authors: Zachara
authors: Carlo
authors: C
authors: Rapezzi
authors: Ali K
authors: AK
authors: Sulafa
authors: Loredana
authors: L
authors: Sutera
authors: Caterina
authors: C
authors: Pizzuto
authors: Claudia
authors: C
authors: Stollberger
authors: Luca
authors: L
authors: Sormani
authors: Joseph
authors: J
authors: Finsterer
authors: Abraham
authors: A
authors: Benatar
authors: Gabriele
authors: G
authors: Di Gesaro
authors: Caterina
authors: C
authors: Cascio
authors: Debora
authors: D
authors: Cangemi
authors: Yuksel
authors: Y
authors: Cavusoglu
authors: Magnus
authors: M
authors: Baumhakel
authors: Fabrizio
authors: F
authors: Drago
authors: Scipione
authors: S
authors: Carerj
authors: Salvatore
authors: S
authors: Pipitone
authors: Salvatore
authors: S
authors: Novo
mesh_terms: D000328:Adult; D002675:Child, Preschool; D004562:Electrocardiography; D005260:Female; D006330:Heart Defects, Congenital / Q000150:complications*; D006801:Humans; D007558:Italy / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D012042:Registries; D012189:Retrospective Studies; D012307:Risk Factors; D017180:Tachycardia, Ventricular / Q000453:epidemiology / Q000209:etiology*