title: Catalytic asymmetric formation of beta-sultams.
abstract: beta-Sultams, highly strained sulfonyl analogues of beta-lactams, were prepared enantio- and diastereoselectively by tertiary amine catalyzed [2 + 2] cycloaddition reactions. The title compounds are practical precursors of highly enantioenriched biologically interesting beta-aminosulfonyl derivatives.
authors: Laboratory of Organic Chemistry, ETH Zürich, Wolfgang-Pauli-Strasse 10, Hönggerberg HCI E 111, Zürich, Switzerland.
authors: Marian
authors: M
authors: Zajac
authors: René
authors: R
authors: Peters
mesh_terms: D002384:Catalysis; D018360:Crystallography, X-Ray; D008958:Models, Molecular; D015394:Molecular Structure; D013237:Stereoisomerism; D013441:Sulfinic Acids / Q000737:chemistry; D013449:Sulfonamides / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D013441:Sulfinic Acids; D013449:Sulfonamides; C480101:beta-sultam; C044255:sulfonyl chloride