title: White matter changes in Leber's hereditary optic neuropathy: MRI findings.
abstract: Leber's hereditary optic neuropathy is a mitochondrial disorder causing bilateral optic nerve degeneration. It is sometimes associated with clinical signs of multiple sclerosis. We report MRI findings in two patients with LHON-MS and comment on possible distinguishing features of this disease entity.
authors: Department of Neuroradiology, The Radcliffe Infirmary, Oxford, UK. Wilhelm.Kuker@ndm.ox.ac.uk
authors: W
authors: W
authors: Küker
authors: A
authors: A
authors: Weir
authors: G
authors: G
authors: Quaghebeur
authors: J
authors: J
authors: Palace
mesh_terms: D000328:Adult; D001921:Brain / Q000473:pathology* / Q000503:physiopathology; D003937:Diagnosis, Differential; D018450:Disease Progression; D042241:Early Diagnosis; D005260:Female; D020233:Gait Disorders, Neurologic / Q000209:etiology / Q000473:pathology / Q000503:physiopathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000473:pathology / Q000503:physiopathology; D009413:Nerve Fibers, Myelinated / Q000473:pathology*; D029242:Optic Atrophy, Hereditary, Leber / Q000175:diagnosis* / Q000473:pathology / Q000503:physiopathology; D009900:Optic Nerve / Q000473:pathology* / Q000503:physiopathology; D011237:Predictive Value of Tests; D012678:Sensation Disorders / Q000209:etiology / Q000473:pathology / Q000503:physiopathology; D015354:Vision, Low / Q000209:etiology / Q000473:pathology / Q000503:physiopathology