Down syndrome and esophageal cancer.
We present two cases of Down syndrome with inoperable esophageal cancer at a relatively young age. The first patient had a locally advanced squamous cell carcinoma of the distal esophagus. The second had a short circular adenocarcinoma of the distal esophagus with peritoneal and liver metastases. The cases are discussed with regard to the current literature on Down syndrome and esophageal cancer.
Moreels
T G
TG
Department of Gastroenterology & Hepatology, Erasmus MC-University Medical Center, Rotterdam, The Netherlands.
van Vliet
E P M
EP
Tilanus
H W
HW
Tran
T C K
TC
Kuipers
E J
EJ
Siersema
P D
PD
D000230:Adenocarcinoma / Q000150:complications* / Q000175:diagnosis; D000328:Adult; D002294:Carcinoma, Squamous Cell / Q000150:complications* / Q000175:diagnosis; D003680:Deglutition Disorders / Q000209:etiology; D004314:Down Syndrome / Q000150:complications*; D016145:Endoscopy, Digestive System; D004938:Esophageal Neoplasms / Q000150:complications* / Q000175:diagnosis; D006801:Humans; D008113:Liver Neoplasms / Q000175:diagnosis / Q000556:secondary; D008297:Male; D010534:Peritoneal Neoplasms / Q000175:diagnosis / Q000556:secondary