[Relationship between pulse pressure, pulse pressure index and prevalence of stroke among rural population in China].
OBJECTIVE
To investigate the association between pulse pressure (PP), pulse pressure index (PPI), and stroke in rural areas.


METHODS
29970 people>or=35 years old in rural areas of Fuxin City, Liaoning Province, were selected by cluster multistage sampling. Blood pressure was measured. History of stroke was taken. SPSS11.5 statistical software was used for data analysis.


RESULTS
(1) The prevalence of stroke was 2.48%. (2) The PP level of the stroke group was 65 mm Hg+/-19 mm Hg in men and 70 mm Hg+/-21 mm Hg in women; while the PP level of the non-stroke group was 52 mm Hg+/-14 mm Hg in men and 53 mm Hg+/-17 mm Hg in women. The PPI level of the stroke group was 0.40+/-0.08 in men and 0.42+/-0.08 in women; while the PPI of the non-stroke was 0.38+/-0.07 in men and 0.39+/-0.07 in women. The PP and PPI levels of the stroke group were significantly higher than those of the non-stroke group (both P<0.01). (2) The prevalence of stroke increased along with the increase of PP and PPI in both genders (both P<0.01). (3) Receiver operating characteristic (ROC) curve analysis showed that the areas of PP and PPI under ROC curve was 0.720 (95% CI, 0.694-0.746) and 0.581 (95% CI, 0.553-0.610) in men when the optional cutoff was selected; and were 0.755 (95% CI, 0.727-0.784) and 0.681 (95% CI, 0.583-0.650) in women. The sensitivity in prediction of stroke of PP was higher than that of PPI; and the specificity in prediction of stroke of PP was lightly lower than that of PPI in men and was higher than that of PP in women. The area of PP under ROC curve was significantly larger than that of PPI (P<0.01).


CONCLUSIONS
As risk factors of stroke, PP and PPI are associated with the prevalence of stroke. PP is superior to PPI in predicting the prevalence of stroke.
Zhang
Xin-gang
XG
Department of Cardiology, Shengjing Hospital of China Medical University, Shenyang 110004, China.
Sun
Zhao-qing
ZQ
Zheng
Li-qiang
LQ
Li
Jue
J
Zhang
Xin-zhong
XZ
Liu
Shuang-shuang
SS
Hu
Da-yi
DY
Sun
Ying-xian
YX
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001794:Blood Pressure; D002681:China / Q000453:epidemiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012307:Risk Factors; D012424:Rural Population / Q000706:statistics & numerical data*; D020521:Stroke / Q000453:epidemiology* / Q000503:physiopathology; D011795:Surveys and Questionnaires