title: New-onset priapism associated with ingestion of terazosin in an otherwise healthy man.
abstract: BACKGROUND
  Priapism has been reported as a rare effect of the commonly used alpha 1-antagonists through direct inhibition of the sympathetic input necessary for detumescence. Although previously reported as an adverse event in a patient with spinal cord injury, to the best of our knowledge, terazosin-induced priapism in an otherwise healthy man has not been previously described.
  
  
  OBJECTIVE
  We describe an otherwise healthy man with lower urinary symptoms who developed priapism after ingestion of the commonly prescribed alpha-blocker terazosin.
  
  
  RESULTS
  The priapism resolved after a combination of cavernosal aspiration and alpha-agonist administration.
  
  
  CONCLUSIONS
  Priapism is an extremely rare side effect of alpha-blocker therapy and has previously been described in association with other alpha-blockers, as well as with terazosin, in a spinal cord-injured patient. We report a case of priapism specifically associated with terazosin prescribed for lower urinary tract symptoms in an otherwise healthy man.
authors: UMDNJ New Jersey Medical School--Surgery, Division of Urology, Newark, NJ 07103-2714, USA. hossein@ix.netcom.com
authors: Hossein
authors: H
authors: Sadeghi-Nejad
authors: Imani
authors: I
authors: Jackson
mesh_terms: D000317:Adrenergic alpha-Antagonists / Q000008:administration & dosage / Q000009:adverse effects*; D000328:Adult; D006304:Health Status; D006801:Humans; D008297:Male; D011224:Prazosin / Q000008:administration & dosage / Q000009:adverse effects / Q000031:analogs & derivatives*; D011317:Priapism / Q000139:chemically induced*; D001745:Urinary Bladder Diseases / Q000188:drug therapy
chemical_list: D000317:Adrenergic alpha-Antagonists; C041226:Terazosin; D011224:Prazosin