[Antiparasitic vaccines: where are we now?].
In more than one way, the development of antiparasitic vaccines is challenging, but major efforts have been made. A large number of clinical trials have been carried out and a few antigens have been tested in the endemic zone, especially against malaria. So far, no vaccine candidate has shown a sufficient and long-lasting effectiveness that would be useful for public health. However, the trials have shown without ambiguity that a certain level of clinical immunity against paludism, schistosomiasis or leishmaniasis could be induced by vaccination, in the experimental setting or in the field.
Rogier
Christophe
C
Unité de recherche en biologie et épidémiologie parasitaires, Institut de médecine tropicale du service de santé des Armies, le Pharo, BP 46, 13998 Marseille-Armées. christophe.rogier@wanadoo.fr
Moukoko
Carole Else Eboumbou
CE
Orlandi-Pradines
Eve
E
Briolant
Sébastien
S
D006801:Humans; D007896:Leishmaniasis / Q000517:prevention & control; D008288:Malaria / Q000517:prevention & control; D010272:Parasitic Diseases / Q000517:prevention & control*; D016052:Protozoan Vaccines; D014612:Vaccines
D016052:Protozoan Vaccines; D014612:Vaccines