Diastereoselective reductive amination of aryl trifluoromethyl ketones and alpha-amino esters.
Hughes
Greg
G
Merck Frosst, Process Research, 16711 Trans Canada Highway, Kirkland H9H 3L1, Canada. greg_hughes@merck.com
Devine
Paul N
PN
Naber
John R
JR
O'shea
Paul D
PD
Foster
Bruce S
BS
McKay
Daniel J
DJ
Volante
R P
RP
D017607:Aluminum Compounds; D000588:Amines / Q000737:chemistry*; D000596:Amino Acids / Q000737:chemistry*; D002851:Chromatography, High Pressure Liquid; D004952:Esters / Q000138:chemical synthesis*; D007202:Indicators and Reagents; D007659:Ketones / Q000737:chemistry*; D018020:Lithium Compounds; D009682:Magnetic Resonance Spectroscopy; D008958:Models, Molecular; D010084:Oxidation-Reduction; D013237:Stereoisomerism
D017607:Aluminum Compounds; D000588:Amines; D000596:Amino Acids; D004952:Esters; D007202:Indicators and Reagents; D007659:Ketones; D018020:Lithium Compounds; C042073:lithium aluminum hydride