title: [Comparative evaluation of Hebei HIV-1 p24 kit for the detection of human immunodeficiency virus].
abstract: OBJECTIVE
  To probe into the feasibility of screening anti-HIV compounds by using HIV-1 p24 detection kit made by Hebei Medical University.
  
  
  METHODS
  The sensitivity, reproducibility and efficacy of the Hebei p24 kit were evaluated compared with the commercially available Vironostika HIV-1 Antigen Microelisa System (Biomerieux).
  
  
  RESULTS
  Hebei p24 kit had high sensitivity and good reproducibility. In vitro screening demonstrated that there was no statistically significant difference (P greater than 0.05) between these two kits in assessing anti-HIV compounds.
  
  
  CONCLUSIONS
  Hebei p24 kit could be used as an easily affordable alternative method for detection of HIV-1 in screening anti-HIV compounds.
authors: College of Life Science and Bio-engineering, Beijing University of Technology, Beijing 100022, China.
authors: Yi-shu
authors: YS
authors: Yang
authors: Run-tian
authors: RT
authors: Wang
authors: Xiao-guang
authors: XG
authors: Zhang
authors: Hong-zhong
authors: HZ
authors: Zhang
authors: Hui-fen
authors: HF
authors: Wang
authors: Ze-lin
authors: ZL
authors: Li
authors: Yi
authors: Y
authors: Zeng
mesh_terms: D019380:Anti-HIV Agents / Q000302:isolation & purification / Q000494:pharmacology*; D002460:Cell Line; D004353:Drug Evaluation, Preclinical / Q000295:instrumentation / Q000379:methods; D005240:Feasibility Studies; D016655:HIV Core Protein p24 / Q000032:analysis*; D015497:HIV-1 / Q000187:drug effects* / Q000254:growth & development / Q000276:immunology; D006801:Humans; D011933:Reagent Kits, Diagnostic / Q000592:standards*; D015203:Reproducibility of Results
chemical_list: D019380:Anti-HIV Agents; D016655:HIV Core Protein p24; D011933:Reagent Kits, Diagnostic