1-Benzotriazol-1-yl-3,3,3-trifluoro-2-methoxy-2- phenylpropan-1-ones: Mosher-Bt reagents.
Benzotriazole derivatives of 3,3,3-trifluoro-2-methoxy-2-phenylpropionic acid react with water-soluble amino acids and peptides in an acetonitrile/water (2:1) mixture to give the corresponding amides in quantitative yield.
Katritzky
Alan R
AR
Center for Heterocyclic Compounds, Department of Chemistry, University of Florida, Gainesville, Florida 32611-7200, USA. katritzky@chem.ufl.edu
Mohapatra
Prabhu P
PP
Fedoseyenko
Dmytro
D
Duncton
Matthew
M
Steel
Peter J
PJ