title: Pt(II)-catalyzed synthesis of 1,2-dihydropyridines from aziridinyl propargylic esters.
abstract: Pt(II)-catalyzed cycloisomerization of aziridinyl propargylic esters affords 1,2-dihydropyridines with regiodefined installation of substituents. A mild conversion of the 1,2-dihydropyridines to the corresponding substituted pyridines as well as chirality retention from the aziridinyl propargylic ester substrates have been demonstrated.
authors: Department of Chemistry, University of California, Berkeley, California 94720, USA.
authors: Massoud
authors: M
authors: Motamed
authors: Eric M
authors: EM
authors: Bunnelle
authors: Surendra W
authors: SW
authors: Singaram
authors: Richmond
authors: R
authors: Sarpong
mesh_terms: D002384:Catalysis; D004095:Dihydropyridines / Q000138:chemical synthesis*; D008958:Models, Molecular; D015394:Molecular Structure; D010984:Platinum / Q000737:chemistry*
chemical_list: D004095:Dihydropyridines; D010984:Platinum