[Can bariatric surgery cure metabolic syndrome?].
OBJECTIVE
To evaluate the impact of bariatric surgery on the metabolic syndrome (MS) and what are the criteria that contribute the most for its exclusion after surgery. The progress of leucometry was also analyzed.


METHODS
47 obese women with MS were evaluated. All patients were operated with the Roux-en-Y vertical gastric bypass technique, with the insertion of a contention ring on the gastro-jejune anastomosis (Fobi-Capella). Patients were evaluated before and on the first year post-surgery.


RESULTS
Fasting glucose presented a relevant decrease at 3 months after surgery. After 12 months, all 20 patients who had DM2 or altered fasting glucose presented normal levels of fasting glucose and glicated hemoglobin, and none of them was using any anti-diabetic drug. Triglycerides levels were reduced by 49.2%, whereas HDL-cholesterol increased by 27.2%. Systolic and diastolic blood pressures were reduced by an average of 28.7 and 20.8 mmHg, respectively. Leucocytes counting fell from 7671/microL to 6156/microL. Fasting glucose, triglycerides, DBP, SBP and HDL-cholesterol were the variables that contributed most for the reduction of MS. At the end of the first year, elimination of MS occurred in 80.9% of the patients.


CONCLUSIONS
Bariatric surgery reduces resistance to insulin and consequently the cardiovascular risk factors.
Carvalho
Perseu Seixas de
PS
Serviço de Endocrinologia, Hospital Universitário Cassiano Antônio Moraes. perseu@npd.ufes.br
Moreira
Cora Lavigne de C B
CL
Barelli
Melina da Costa
Mda C
Oliveira
Flávia Heringer de
FH
Guzzo
Mariana Furieri
MF
Miguel
Gustavo P Soares
GP
Zandonade
Eliana
E
D000328:Adult; D015415:Biomarkers / Q000097:blood; D001786:Blood Glucose / Q000502:physiology; D015992:Body Mass Index; D008076:Cholesterol, HDL / Q000097:blood; D005260:Female; D015390:Gastric Bypass / Q000379:methods; D006801:Humans; D007333:Insulin Resistance / Q000502:physiology; D024821:Metabolic Syndrome / Q000601:surgery*; D009767:Obesity, Morbid / Q000145:classification / Q000601:surgery*; D011182:Postoperative Care; D011300:Preoperative Care; D013997:Time Factors; D016896:Treatment Outcome; D014280:Triglycerides / Q000097:blood; D049629:Waist-Hip Ratio
D015415:Biomarkers; D001786:Blood Glucose; D008076:Cholesterol, HDL; D014280:Triglycerides