Lack of electrocardiographic changes in women with polycystic ovary syndrome.
OBJECTIVE
The aim of the present study was to investigate the potential alterations in electrocardiographic (ECG) pattern in patients with polycystic ovary syndrome (PCOS).


METHODS
Fifty PCOS patients and 50 age- and body mass index-matched healthy women were studied.


METHODS
We assessed hormonal and metabolic pattern, and performed ECG analysis for evaluating PQ interval, QRS duration, minimum and maximum QT interval corrected for heart rate (QT(c)min and QT(c)max, respectively), corrected QT dispersion (QT(c)d), corrected J point/T-wave interval (JTend(c)), corrected JTmax interval (JTmax(c)), and corrected Tmax-end interval (Tmax-end(c)).


RESULTS
QT(c)min (399 +/- 21 vs. 396 +/- 25 ms, P = 0.51); QT(c) max (445 +/- 25 vs. 443 +/- 27 ms, P = 0.70); and QT(c)d (46 +/- 13 vs. 47 +/- 15 ms, P = 0.72); JTend(c) (337 +/- 14 vs. 336 +/- 16 ms(1/2), P = 0.74); and JTmax(c) (256 +/- 22 vs. 258 +/- 21 ms(1/2), P = 0.64); Tmax-end(c) (81 +/- 18 vs. 78 +/- 19 ms(1/2), P = 0.42) were not significantly different between PCOS and healthy women.


CONCLUSIONS
Despite profound differences in hormonal and metabolic pattern, our data demonstrate no significant difference in ECG pattern in PCOS compared to healthy controls.
Orio
Francesco
F
Department of Molecular & Clinical Endocrinology and Oncology, University Federico II of Naples, Naples, Italy. francescoorio@virgilio.it
Palomba
Stefano
S
Cascella
Teresa
T
Manguso
Francesco
F
Vuolo
Laura
L
Tafuri
Domenico
D
Vigorito
Carlo
C
Lombardi
Gaetano
G
Liguori
Vincenzo
V
Colao
Annamaria
A
Giallauria
Francesco
F
D000328:Adult; D016022:Case-Control Studies; D004562:Electrocardiography; D005260:Female; D006321:Heart / Q000502:physiology*; D006339:Heart Rate; D006801:Humans; D008875:Middle Aged; D011085:Polycystic Ovary Syndrome / Q000503:physiopathology*