title: Cortical sources of awake scalp EEG in eating disorders.
abstract: OBJECTIVE
  To investigate quantitative EEG (qEEG) in anorexia nervosa (AN) and bulimia nervosa (BN) in comparison with healthy controls.
  
  
  METHODS
  Resting EEG was recorded in 30 healthy females (age: 27.1+/-5.5), 16-AN females (age: 26.4+/-9.5) and 12-BN females (age: 27.0+/-6.3). Cortical EEG sources (delta, theta, alpha 1, alpha 2, beta 1, beta 2) were modeled by LORETA solutions. The statistical analysis was performed considering the factors Group, power Band, and region of interest (central, frontal, parietal, occipital, temporal, limbic).
  
  
  RESULTS
  Alpha 1 sources in central, parietal, occipital and limbic areas showed a greater amplitude in Controls versus AN and BN groups. Alpha 2 sources in parietal, occipital and limbic areas showed a greater amplitude in Controls than in both AN and BN groups. Alpha 1 sources in temporal area showed a greater amplitude in Controls compared to both the BN and AN groups as well as in the BN group compared to AN group. Central alpha 1 source correlated significantly with BMI in patients.
  
  
  CONCLUSIONS
  These results support the hypothesis that eating disorders are related to altered mechanisms of cortical neural synchronization, especially in rolandic alpha rhythms.
  
  
  CONCLUSIONS
  To our knowledge this is the first study by LORETA able to detect modifications of cortical EEG activity in eating disorders.
authors: Section of Clinical Neurophysiology (DISEM), Department of Endocrinological and Metabolic Sciences, University of Genoa, Genoa, Italy. guido@unige.it
authors: Guido
authors: G
authors: Rodriguez
authors: Claudio
authors: C
authors: Babiloni
authors: Andrea
authors: A
authors: Brugnolo
authors: Claudio
authors: C
authors: Del Percio
authors: Fabrizio
authors: F
authors: Cerro
authors: Filippo
authors: F
authors: Gabrielli
authors: Nicola
authors: N
authors: Girtler
authors: Flavio
authors: F
authors: Nobili
authors: Giovanni
authors: G
authors: Murialdo
authors: Paolo M
authors: PM
authors: Rossini
authors: Davide Sebastiano
authors: DS
authors: Rossi
authors: Chiara
authors: C
authors: Baruzzi
authors: Antonio Maria
authors: AM
authors: Ferro
mesh_terms: D000293:Adolescent; D000328:Adult; D000704:Analysis of Variance; D000856:Anorexia Nervosa / Q000503:physiopathology*; D001931:Brain Mapping; D052018:Bulimia Nervosa / Q000503:physiopathology*; D002540:Cerebral Cortex / Q000503:physiopathology*; D002648:Child; D004569:Electroencephalography; D005260:Female; D006801:Humans; D012535:Scalp; D013057:Spectrum Analysis; D018709:Statistics, Nonparametric; D014054:Tomography / Q000379:methods