title: Photoisomerization mechanism of rhodopsin and 9-cis-rhodopsin revealed by x-ray crystallography.
abstract: The primary photochemical process of the visual function has been investigated using the three crystallographic models, 11-cis-rhodopsin, all-trans-bathorhodopsin, and the artificial isomeric 9-cis-rhodopsin. Detailed examination of the atomic displacements and dihedral angle changes of the retinal chromophore involved in the interconversion among these isomers suggests the mechanism of isomerization efficiency.
authors: Biological Information Research Center, National Institute of Advanced Industrial Science and Technology, Tokyo, Japan.
authors: Hitoshi
authors: H
authors: Nakamichi
authors: Volker
authors: V
authors: Buss
authors: Tetsuji
authors: T
authors: Okada
mesh_terms: D003198:Computer Simulation; D018360:Crystallography, X-Ray / Q000379:methods*; D007536:Isomerism; D008956:Models, Chemical; D008958:Models, Molecular; D010777:Photochemistry / Q000379:methods*; D011487:Protein Conformation / Q000528:radiation effects; D012243:Rhodopsin / Q000737:chemistry* / Q000528:radiation effects / Q000648:ultrastructure*
chemical_list: D012243:Rhodopsin