title: Conversion of flavodoxin from holoenzyme to apoprotein during growth phase changes in Helicobacter pylori.
abstract: The catabolic pathway for flavodoxin has yet to be clarified for any bacterial species. In this study, we found that the flavin mononucleotide in the flavodoxin of Helicobacter pylori is degraded to riboflavin via the phosphomonoesterase activity of class C acid phosphatase. The result is a conversion of holoflavodoxin to apoflavodoxin.
authors: Division of Bacteriology, Department of Infection and Immunity, Jichi Medical University, 3311-1 Yakushiji, Shimotsuke-shi, Tochigi 329-0498, Japan. shimo@jichi.ac.jp
authors: Hirofumi
authors: H
authors: Shimomura
authors: Shunji
authors: S
authors: Hayashi
authors: Kenji
authors: K
authors: Yokota
authors: Keiji
authors: K
authors: Oguma
authors: Yoshikazu
authors: Y
authors: Hirai
mesh_terms: D001059:Apoproteins / Q000737:chemistry / Q000378:metabolism*; D001426:Bacterial Proteins / Q000737:chemistry / Q000378:metabolism; D005486:Flavin Mononucleotide / Q000737:chemistry / Q000378:metabolism; D005418:Flavodoxin / Q000737:chemistry / Q000378:metabolism*; D016480:Helicobacter pylori / Q000254:growth & development / Q000378:metabolism*; D020035:Holoenzymes / Q000737:chemistry / Q000378:metabolism*; D010766:Phosphorylation; D012256:Riboflavin / Q000737:chemistry / Q000378:metabolism; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
chemical_list: D001059:Apoproteins; D001426:Bacterial Proteins; D005418:Flavodoxin; D020035:Holoenzymes; C026932:apoflavodoxin; D005486:Flavin Mononucleotide; D012256:Riboflavin