title: Hernia repair with porcine small-intestinal submucosa.
abstract: OBJECTIVE
  Although at present nonabsorbable meshes are the preferred material for tension-free hernioplasty, some problems with their use have yet to be addressed (i.e., chronic pain and infections). In order to address these disadvantages, a collagen-based material, the porcine small-intestinal submucosa mesh (Surgisis Inguinal Hernia Matrix, Cook Surgical, Bloomington, IN, USA), has recently been developed for hernia repair.
  
  
  METHODS
  With the aim of investigating the clinical safety and effectiveness of Surgisis IHM inguinal hernia repair, we report our experience of 45 consecutive hernioplasties with a medium-term follow-up. The surgical technique for the use of this material in hernioplasty is described in detail.
  
  
  RESULTS
  Although some local (i.e., seromas) and general (i.e., hyperpyrexia), complications appeared in the immediate postoperative period (all of them disappeared spontaneously), no rejection or infection was observed after operations. At the 2-year follow-up, a low degree of pain and discomfort and no recurrences were observed.
  
  
  CONCLUSIONS
  We conclude that the Surgisis IHM hernioplasty is feasible with promising results and, from a clinical perspective, seems safe and effective.
authors: Unit of General, Transplant and Emergency Surgery, St. Orsola-Malpighi University Hospital, Via Massarenti 9, 40138 Bologna, Italy. lansaloni@aosp.bo.it
authors: L
authors: L
authors: Ansaloni
authors: F
authors: F
authors: Catena
authors: S
authors: S
authors: Gagliardi
authors: F
authors: F
authors: Gazzotti
authors: L
authors: L
authors: D'Alessandro
authors: A D
authors: AD
authors: Pinna
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001705:Bioprosthesis; D005240:Feasibility Studies; D005260:Female; D005500:Follow-Up Studies; D006552:Hernia, Inguinal / Q000601:surgery*; D006801:Humans; D007413:Intestinal Mucosa / Q000637:transplantation*; D007421:Intestine, Small; D008297:Male; D008875:Middle Aged; D011474:Prosthesis Design; D019919:Prosthesis Implantation / Q000379:methods*; D016896:Treatment Outcome