title: The use of Surgisis for abdominal wall reconstruction in the separation of omphalopagus conjoined twins.
abstract: Abdominal wall reconstruction in omphalopagus twins poses a difficult reconstructive challenge, as separation often results in a large abdominal wall defect. A number of options are available for closure, including tissue flaps, expanders and patches made of foreign material. Surgisis is a new biodegradable small intestine scaffolding substrate that permits tissue in-growth and results in a permanent durable scar. We describe its use in abdominal wall reconstruction after separation of a set of conjoined twins. A set of omphalopagus conjoined twins shared liver and abdominal wall. After separation at 6 months of age, Twin A's abdomen could be closed primarily, but Twin B could not. A 4-ply Surgisis mesh was used in the upper abdominal closure, and a skin flap was created, to completely cover the patch. Both twins survived the operation. A small portion of the skin flap over the Surgisis broke down, healing by secondary intention. In follow up of over 18 months post procedure, there have been no wound infections and the abdominal wall is intact with no evidence of a hernia. Surgisis can be successfully used for the reconstruction of complex abdominal wall defects in the pediatric patient, including reconstruction after separation of conjoined twins.
authors: Division of Pediatric General Surgery, Hospital for Sick Children, Toronto, ON, Canada. roshni.dasgupta@cchmc.org
authors: Roshni
authors: R
authors: Dasgupta
authors: Paul W
authors: PW
authors: Wales
authors: Ronald M
authors: RM
authors: Zuker
authors: David M
authors: DM
authors: Fisher
authors: Jacob C
authors: JC
authors: Langer
mesh_terms: D034861:Abdominal Wall / Q000002:abnormalities / Q000601:surgery*; D001672:Biocompatible Materials; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D007421:Intestine, Small / Q000601:surgery; D008099:Liver / Q000002:abnormalities / Q000601:surgery; D008297:Male; D019651:Plastic Surgery Procedures / Q000379:methods*; D013526:Surgical Mesh; D014428:Twins, Conjoined / Q000601:surgery*
chemical_list: D001672:Biocompatible Materials