title: Validation of metal oxide semiconductor field effect transistor technology for organ dose assessment during CT: comparison with thermoluminescent dosimetry.
abstract: OBJECTIVE
  The purposes of this study were to apply near-real-time dose-measurement technology with metal oxide semiconductor field effect transistors (MOSFETs) to the assessment of organ dose during CT and to validate the method in comparison with the thermoluminescent dosimeter (TLD) method.
  
  
  METHODS
  Dosimetry measurements were performed in two ways, one with TLDs and the other with MOSFETs. Twenty organ locations were selected in an adult anthropomorphic female phantom. High-sensitivity MOSFET dosimeters were used. For the reference standard, TLDs were placed in the same organ locations as the MOSFETs. Both MOSFET and TLD detectors were calibrated with an X-ray beam equivalent in quality to that of a commercial CT scanner (half-value layer, approximately 7 mm Al at 120 kVp). Organ dose was determined with a scan protocol for pulmonary embolus studies on a 4-MDCT scanner.
  
  
  RESULTS
  Measurements for selected organ doses and the percentage difference for TLDs and MOSFETs, respectively, were as follows: thyroid (0.34 cGy, 0.31 cGy, -8%), middle lobe of lung (2.4 cGy, 3.0 cGy, +26%), bone marrow of thoracic spine (2.2 cGy, 2.5 cGy, +11%), stomach (1.0 cGy, 0.93 cGy, -6%), liver (2.5 cGy, 2.6 cGy, +6%), and left breast (3.0 cGy, 2.9 cGy, -1%). Bland-Altman analysis showed that the MOSFET results agreed with the TLD results (bias, 0.042).
  
  
  CONCLUSIONS
  We found good agreement between the results with the MOSFET and TLD methods. Near-real-time CT organ dose assessment not previously feasible with TLDs was achieved with MOSFETs. MOSFET technology can be used for protocol development in the rapidly changing MDCT scanner environment, in which organ dose data are extremely limited.
authors: Department of Radiology, Duke University Medical Center, Box 3155, Durham, NC 27710, USA. yoshi003@mc.duke.edu
authors: Terry T
authors: TT
authors: Yoshizumi
authors: Philip C
authors: PC
authors: Goodman
authors: Donald P
authors: DP
authors: Frush
authors: Giao
authors: G
authors: Nguyen
authors: Greta
authors: G
authors: Toncheva
authors: Maksudur
authors: M
authors: Sarder
authors: Lottie
authors: L
authors: Barnes
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D019047:Phantoms, Imaging; D011829:Radiation Dosage; D011874:Radiometry / Q000379:methods*; D012666:Semiconductors; D013819:Thermoluminescent Dosimetry; D014057:Tomography, X-Ray Computed; D014173:Transistors, Electronic