[Microarray and research of Chinese medications: pharmcogenomics of Chinese medications].
The mechanism of Chinese medications have some characteristic such as multi-pathway, multi-components, multi-targets and so on, which decide the direction of systems research. In the recent years, microarrays be concerned with the relative field of Chinese medications for its superiority of highthough, parallel and high-density. This paper mainly generalize the approach of these methods in the recent three years, such as finding effective target of Chinese medications, effective part of Chinese medications, checkup of Chinese medications, screening new drugs and so on. We suggest the concept of Pharmacogenomics of Chinese medications with the guidance of the theory of Chinese medications for further development of Chinese medications.
Jing
Zhi-Wei
ZW
Institute of Clinical Fundational Chinese Medicine, China Academy of Chinese Medicine Science, Beijing 100700, China.
Wang
Zhong
Z
Gao
Si-Hua
SH
Wang
Yong-Yan
YY
D000818:Animals; D004353:Drug Evaluation, Preclinical; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology; D020869:Gene Expression Profiling; D023281:Genomics / Q000379:methods*; D006801:Humans; D008962:Models, Theoretical; D020411:Oligonucleotide Array Sequence Analysis; D010597:Pharmacogenetics / Q000379:methods; D010946:Plants, Medicinal / Q000737:chemistry / Q000235:genetics* / Q000378:metabolism
D004365:Drugs, Chinese Herbal