title: Pulmonary cryptococcosis presenting as endobronchial lesions in a patient under corticosteroid treatment.
abstract: We report a case of pulmonary cryptococcosis in an immunocompromised patient who had focal endobronchial lesions. When we first examined her, she complained of a productive cough that had lasted for two months. Seventeen months prior to this examination, she had been diagnosed with Sjogren syndrome and Sweet syndrome. Since that diagnosis, her condition had been maintained with low-dose prednisolone. We performed a chest CT scan, which revealed a mass, 3 cm in diameter, in the upper lobe of her left lung. A bronchoscopic examination revealed 3 white, elevated lesions in the upper lobe bronchus of her left lung. After 40 days of treatment with fluconazole, the shadow of her lung mass decreased in size to that of a scarred lesion and her white, elevated bronchial lesions disappeared.
authors: Department of Internal Medicine, Isahaya Insurance General Hospital, Nagasaki. naika02@hospital-isahayasougou.jp
authors: Yuichi
authors: Y
authors: Inoue
authors: Yoshitsugu
authors: Y
authors: Miyazaki
authors: Kohichi
authors: K
authors: Izumikawa
authors: Katsunori
authors: K
authors: Yanagihara
authors: Hiroshi
authors: H
authors: Kakeya
authors: Toyomitsu
authors: T
authors: Sawai
authors: Yoichi
authors: Y
authors: Hirakata
authors: Shigeru
authors: S
authors: Kohno
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use*; D000935:Antifungal Agents / Q000627:therapeutic use; D001980:Bronchi / Q000382:microbiology / Q000473:pathology*; D003453:Cryptococcosis / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000188:drug therapy; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D016867:Immunocompromised Host / Q000187:drug effects; D008172:Lung Diseases, Fungal / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000188:drug therapy; D008875:Middle Aged; D011859:Radiography
chemical_list: D000305:Adrenal Cortex Hormones; D000935:Antifungal Agents