Rhizopus microsporus var. rhizopodiformis sinus-orbital zygomycosis in an immunosuppressed patient: successful treatment with posaconazole after a complicated clinical course.
A case of sinus-orbital Rhizopus microsporus var. rhizopodiformis infection in a patient with graft versus host disease following allogeneic blood stem cell transplantation is reported. Commercially available pea straw compost used for gardening was suspected to be the source of the infection. After an initial relapse, treatment with surgical debridement, liposomal amphotericin B and posaconazole was successful.
Stark
D
D
Department of Microbiology, St Vincent's Hospital, Sydney, Australia.
Milliken
S
S
Department of Haematology, St Vincent's Hospital, Sydney, Australia.
Marriott
D
D
Department of Microbiology, St Vincent's Hospital, Sydney, Australia.
Harkness
J
J
Department of Microbiology, St Vincent's Hospital, Sydney, Australia.
D000328:Adult; D000666:Amphotericin B / Q000627:therapeutic use; D015821:Eye Infections, Fungal / Q000188:drug therapy / Q000382:microbiology*; D006402:Hematologic Diseases / Q000150:complications; D018380:Hematopoietic Stem Cell Transplantation; D006801:Humans; D016867:Immunocompromised Host; D008297:Male; D009916:Orbital Diseases / Q000188:drug therapy / Q000382:microbiology*; D010254:Paranasal Sinus Diseases / Q000188:drug therapy / Q000382:microbiology*; D012233:Rhizopus / Q000187:drug effects / Q000302:isolation & purification*; D012987:Soil; D012988:Soil Microbiology; D014184:Transplantation, Homologous; D014230:Triazoles / Q000627:therapeutic use*; D020096:Zygomycosis / Q000188:drug therapy* / Q000382:microbiology* / Q000601:surgery
D012987:Soil; D014230:Triazoles; C068538:liposomal amphotericin B; C101425:posaconazole; D000666:Amphotericin B