Reaction of 2,3-allenoates with TsNBr2 in the presence of base: a facile highly stereoselective synthesis of (1E,2E)-3-bromo-4-oxo-N'-tosyl-2-alkenoxylimidic acid ethyl esters.
A novel reaction pathway of 2,3-allenoates with an electrophile (TsNBr2) in the presence of K2CO3 to produce (1E,2E)-3-bromo-4-oxo-N'-tosyl-2-alkenoxylimidic acid ethyl esters is reported. The reaction proceeds in a highly stereoselective fashion. A plausible mechanism to rationalize this reaction is also proposed.
Shen
Ruwei
R
Department of Chemistry, Zhejiang University (Xixi Campus), Hangzhou 310028, People's Republic of China.
Huang
Xian
X