title: Quorum sensing enhances the stress response in Vibrio cholerae.
abstract: Vibrio cholerae lives in aquatic environments and causes cholera. Here, we show that quorum sensing enhances V. cholerae viability under certain stress conditions by upregulating the expression of RpoS, and this regulation acts through HapR, suggesting that a quorum-sensing-enhanced stress response plays a role in V. cholerae environmental survival.
authors: Department of Microbiology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.
authors: Adam
authors: A
authors: Joelsson
authors: Biao
authors: B
authors: Kan
authors: Jun
authors: J
authors: Zhu
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology; D019677:Artificial Gene Fusion; D001426:Bacterial Proteins / Q000096:biosynthesis / Q000502:physiology; D015964:Gene Expression Regulation, Bacterial; D017930:Genes, Reporter; D006861:Hydrogen Peroxide / Q000494:pharmacology; D050296:Microbial Viability; D018384:Oxidative Stress; D053038:Quorum Sensing / Q000502:physiology*; D012808:Sigma Factor / Q000096:biosynthesis / Q000502:physiology; D015854:Up-Regulation; D014734:Vibrio cholerae / Q000235:genetics / Q000502:physiology*; D001616:beta-Galactosidase / Q000032:analysis / Q000235:genetics
chemical_list: D000900:Anti-Bacterial Agents; D001426:Bacterial Proteins; D012808:Sigma Factor; C069567:sigma factor KatF protein, Bacteria; D006861:Hydrogen Peroxide; D001616:beta-Galactosidase