Update on the clinical management of childhood lead poisoning.
Childhood lead poisoning is still an enormous public health issue in the United States, affecting thousands of children and their families. New evidence suggests that even very low blood lead levels, less than 10 microg/dL, can be associated with neurologic injury. This article discusses characteristics of children at high risk for lead poisoning, unusual sources of lead contamination, and new aspects of lead's pathophysiology. It includes current thinking on the clinical management and prevention of childhood lead poisoning.
Woolf
Alan D
AD
Harvard Medical School, 25 Shattuck Street, Boston, MA 02115, USA. alan.woolf@childrens.harvard.edu
Goldman
Rose
R
Bellinger
David C
DC
D002614:Chelating Agents / Q000627:therapeutic use; D002648:Child; D002669:Child Welfare / Q000706:statistics & numerical data; D017281:Cost of Illness; D002658:Developmental Disabilities / Q000139:chemically induced; D004781:Environmental Exposure / Q000009:adverse effects / Q000517:prevention & control* / Q000706:statistics & numerical data; D004782:Environmental Health / Q000379:methods* / Q000706:statistics & numerical data; D005506:Food Contamination / Q000517:prevention & control; D006077:Government Agencies; D006801:Humans; D007855:Lead Poisoning / Q000097:blood / Q000150:complications / Q000453:epidemiology / Q000628:therapy*; D008403:Mass Screening; D009483:Neuropsychological Tests; D009749:Nutrition Surveys; D010150:Paint / Q000633:toxicity; D010353:Patient Education as Topic; D010372:Pediatrics / Q000379:methods*; D011322:Primary Prevention; D011634:Public Health / Q000706:statistics & numerical data; D018570:Risk Assessment; D012307:Risk Factors; D014481:United States / Q000453:epidemiology; D014837:Voluntary Health Agencies
D002614:Chelating Agents