Usefulness of cardiovascular investigations in stroke management: clinical relevance and economic implications.
OBJECTIVE
There are no prospective randomized studies assessing the clinical relevance of routine cardiovascular investigations in stroke patients. The objective of this study was to evaluate the utilization, relevance, and economics of cardiovascular investigations in an ambulatory stroke clinic.


METHODS
The outcome of cardiovascular investigations in 200 patients with stroke/transient ischemic attack diagnosed in a stroke prevention clinic was assessed. Transthoracic echocardiography (TTE) was assessed for detection of thrombus or mass, poor left ventricle function, and other structural abnormalities. ECG and Holter monitor were felt to be relevant if they showed atrial fibrillation/flutter. Investigations were deemed to be clinically pertinent if they brought about a shift treatment paradigm.


RESULTS
TTE and Holter were performed in >70% of cases and accounted for approximately 94% of total cardiovascular cost. Relevant TTE findings were identified in 6 (4%) patients, which did not alter antithrombotic therapy. Only 2 new cases of atrial fibrillation were identified by both ECG and Holter.


CONCLUSIONS
TTE and Holter appear to be costly low-yield procedures in this clinical setting. Prospective analyses may help to provide cost effective criteria for selection of appropriate cardiovascular studies in stroke management.
Douen
Andre
A
Pageau
Nicole
N
Medic
Sejla
S
D000553:Ambulatory Care / Q000191:economics; D002318:Cardiovascular Diseases / Q000191:economics / Q000453:epidemiology / Q000628:therapy; D019468:Disease Management; D006801:Humans; D020521:Stroke / Q000191:economics* / Q000453:epidemiology / Q000628:therapy*