[The role of parental translocations in cases of repeated miscarriages].
In families in which spontaneous miscarriages are very frequent, a systematic search for parental translocations must be made. An examination of the karyotype appears to be justified in patients with three or more miscarriages (probabilily of detecting a translocation equal to or greater than 1 percent). The results of cytogenetic analysis will indicate in many cases the prognosis for subsequent pregnancies and will to a large extent determine the procedure to be followed.
Sinet
P M
PM
Institut de Progénèse, 15, rue de l'Ecole de Médecine, 75006 Paris, France.
Dutrillaux
B
B
Prieur
M
M
Lejeune
J
J
D000026:Abortion, Habitual / Q000235:genetics*; D005260:Female; D006801:Humans; D007621:Karyotyping; D011247:Pregnancy; D011379:Prognosis; D014178:Translocation, Genetic