Mitomycin C and conjunctival autograft for recurrent pterygium.
OBJECTIVE
To observe the efficiency of intraoperative low-dose Mitomycin-C combined with conjunctival autograft in the treatment of recurrent pterygium.


METHODS
Fifteen eyes with recurrent pterygium were included in this study. The mean age of the patients was 51.6 +/- 11.4 (9 men, 6 women). All patients underwent excision of the pterygium tissue and subconjunctival fibrous tissue with a no cautery approach. 0.2 mg/ml Mitomycin-C (0.02%) was applied for 3 min. Conjunctival autograft was obtained from the superotemporal bulbar conjunctiva of the same eye. Eyes were followed for a mean period of 21.0 +/- 9.1 months.


RESULTS
Recurrence was seen in two eyes (13.3%) during the follow-up period. The only complication seen was graft edema (two eyes; 13.3%) which healed after pressure patching. Graft necrosis, scleral melting or failure of revascularization was not noted.


CONCLUSIONS
Intraoperative application of 0.2 mg/ml Mitomycin-C combined with conjunctival autograft reduces recurrence in recurrent pterygium cases, with minimal complications.
Altiparmak
Uğur E
UE
Department of Ophthalmology, Ankara Training and Research Hospital, Ankara, Turkey. ealtiparmak@hotmail.com
Katircioğlu
Yasemin Aslan
YA
Yağci
Ramazan
R
Yalniz
Züleyha
Z
Duman
Sunay
S
D000328:Adult; D000368:Aged; D000477:Alkylating Agents / Q000008:administration & dosage*; D003131:Combined Modality Therapy; D003228:Conjunctiva / Q000637:transplantation*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D016685:Mitomycin / Q000008:administration & dosage*; D011625:Pterygium / Q000188:drug therapy* / Q000601:surgery*; D012008:Recurrence; D014182:Transplantation, Autologous
D000477:Alkylating Agents; D016685:Mitomycin