title: Guidelines on the treatment of ABRS in adults.
abstract: Acute bacterial rhinosinusitis (ABRS) is a common reason for healthcare visits, and one of the more common reasons for the use of antibiotics. In an effort to improve the diagnosis and appropriate therapy of ABRS, several guidelines have been developed. Current guidelines recommend extended-spectrum cephalosporins as one of the first-line options for the treatment of this condition. In addition, most cephalosporins recommended by recent guidelines (e.g. cefuroxime axetil, cefpodoxime proxetil and cefdinir) are unlikely to be associated with cross-reactivity with penicillins, and may be considered effective alternatives to amoxicillin in adults who are allergic to penicillin.
authors.affiliation: Henry Ford Health System, Detroit, MI 48202, USA. mbenning@hfhs.org
authors.forename: M
authors.initials: M
authors.lastname: Benninger
mesh_terms: D000208:Acute Disease; D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D001424:Bacterial Infections / Q000188:drug therapy*; D002511:Cephalosporins / Q000627:therapeutic use*; D004342:Drug Hypersensitivity / Q000209:etiology; D006801:Humans; D010406:Penicillins / Q000009:adverse effects; D017410:Practice Guidelines as Topic; D012852:Sinusitis / Q000188:drug therapy*
chemical_list: D000900:Anti-Bacterial Agents; D002511:Cephalosporins; D010406:Penicillins