title: Neuronal vacuolation in an adult ferret.
abstract: The brain of a ferret showing abnormal neurologic signs was evaluated by histopathologic, histochemical, immunohistochemical, and ultrastructural examinations. Extensive neuronal vacuolation was observed. Since the brain was negative for protease-resistant protein prion (PrP'"), it was concluded that this was not a case of transmissible spongiform encephalopathy.
authors.affiliation: National Animal Disease Center, ARS, USDA, 2300 Dayton Road, P.O. Box 70, Ames, Iowa 50010, USA. ahamir@nadc.ars.usda.gov
authors.forename: Amir N
authors.initials: AN
authors.lastname: Hamir
authors.forename: Janice M
authors.initials: JM
authors.lastname: Miller
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Yaeger
mesh_terms: D000818:Animals; D001927:Brain Diseases / Q000175:diagnosis / Q000473:pathology / Q000662:veterinary*; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D005260:Female; D005289:Ferrets; D007150:Immunohistochemistry / Q000662:veterinary; D009474:Neurons / Q000473:pathology* / Q000648:ultrastructure; D014617:Vacuoles / Q000473:pathology* / Q000648:ultrastructure