Nutrition and lung disease in cystic fibrosis.
Among patients who have cystic fibrosis (CF), lung disease is a significant contributor to morbidity. From a clinical perspective, the link between malnutrition and lung dysfunction in CF is well established; however, the causal relationship remains unclear. Nutritional intervention for CF patients is predicated on the hypothesis that improved nutritional status improves pulmonary function. Which interventions will be of most value and have sustained gains is not completely clear from the available data. Taking into account that several factors condition the deficits that lead to malnutrition in CF, multidisciplinary interventions are likely to give the best results. More research is needed to better dissect the nutritional factors involved in lung disease and to identify effective and safe interventions through systematic controlled trials.
Milla
Carlos E
CE
Department of Pediatrics, Center for Excellence in Pulmonary Biology, Stanford University, 770 Welch Road, Palo Alto, CA 94304, USA. cmilla@stanford.edu
D000818:Animals; D015992:Body Mass Index; D003550:Cystic Fibrosis / Q000150:complications* / Q000503:physiopathology; D006801:Humans; D008171:Lung Diseases / Q000150:complications* / Q000503:physiopathology; D009748:Nutrition Disorders / Q000209:etiology* / Q000503:physiopathology / Q000517:prevention & control*; D018529:Nutritional Support / Q000379:methods*