Role of surgery in pediatric epilepsy.
Twenty five percent of patients with intractable epilepsy have surgically remediable epilepsy syndromes. This article reviews the treatment paradigm for pediatric epilepsy and also the indications, methods, and surgical options for the subgroup of patients with surgically remediable epileptic disorders based on our experience in the management of these children. The article also discusses the rationale for offering surgery and the timing of surgery in these patients. The study of surgically remediable epilepsy can best be divided into focal, sub hemispheric, hemispheric and multifocal epileptic syndromes. These syndromes have both acquired and congenital etiologies and can be treated by resective or disconnective surgery. The surgical management of these conditions (with the exception of multifocal epilepsy) provides Engel's Class 1 outcome(complete seizure freedom) in approximately 80% of children. The consequences of seizure freedom leads to a marked improvement in the quality of life of these children. The benefits to society, of allowing a child to grow to adulthood with normal cognition to earn a livelihood and contribute actively to society, cannot be understated.
Daniel
Roy Thomas
RT
Department of Neurological Sciences, Christian Medical College, Vellore, Tamil Nadu, India. roy@cmcvellore.ac.in
Thomas
Santhosh George
SG
Thomas
Maya
M
D002648:Child; D002675:Child, Preschool; D004827:Epilepsy / Q000503:physiopathology / Q000601:surgery*; D038421:Hemispherectomy; D006801:Humans; D010372:Pediatrics; D011788:Quality of Life; D012008:Recurrence; D013997:Time Factors; D016896:Treatment Outcome