Thyrotoxic periodic paralysis in a Polynesian male following highly active antiretroviral therapy for HIV infection.
Hyperthyroidism has been described after highly active antiretroviral therapy for AIDS and has been attributed to late onset immune reconstitution. The team reports a young Polynesian man with AIDS who responded to highly active antiretroviraltherapy. However, 15 months after initiation of antiretroviral therapy, he was hospitalized for hypokalemic thyrotoxic periodic paralysis, an unusual manifestation of hyperthyroidism which typically occurs in young Asian males.
Brown
Joel D
JD
Department of Medicine, The Queens Medical Center, Honolulu, HI 96813, USA. jbrown@queens.org
Kangwanprasert
Monsicha
M
Tice
Alan
A
Melish
John
J
D000163:Acquired Immunodeficiency Syndrome / Q000150:complications* / Q000188:drug therapy; D000328:Adult; D023241:Antiretroviral Therapy, Highly Active / Q000009:adverse effects*; D015551:Autoimmunity / Q000187:drug effects*; D003967:Diarrhea / Q000209:etiology; D004338:Drug Combinations; D020022:Genetic Predisposition to Disease; D006111:Graves Disease / Q000139:chemically induced* / Q000150:complications / Q000532:radiotherapy; D006254:Hawaii; D006801:Humans; D020514:Hypokalemic Periodic Paralysis / Q000175:diagnosis / Q000209:etiology*; D007457:Iodine Radioisotopes / Q000627:therapeutic use; D019259:Lamivudine / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use; D061466:Lopinavir; D008297:Male; D044468:Native Hawaiian or Pacific Islander; D011114:Polynesia / Q000208:ethnology; D011744:Pyrimidinones / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use; D013971:Thyrotoxicosis / Q000139:chemically induced / Q000150:complications*; D015215:Zidovudine / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use
D004338:Drug Combinations; D007457:Iodine Radioisotopes; D011744:Pyrimidinones; C109078:lamivudine, zidovudine drug combination; D061466:Lopinavir; D019259:Lamivudine; D015215:Zidovudine