Gold-catalyzed efficient preparation of linear alpha-iodoenones from propargylic acetates.
Only 2 mol % of Au(PPh3)NTf2 is needed to convert readily accessible propargylic acetates into versatile linear alpha-iodoenones in good to excellent yields. This reaction is easy to execute and has broad substrate scope. Good to excellent Z-selectivities are observed in the cases of aliphatic propargylic acetates derived from aldehydes.
Yu
Meng
M
Department of Chemistry, University of Nevada, Reno, Nevada 89557, USA.
Zhang
Guozhu
G
Zhang
Liming
L