A single episode of neonatal seizures permanently alters glutamatergic synapses.
Holmes
Gregory L
GL
Ben-Ari
Yehezkel
Y
D000818:Animals; D000831:Animals, Newborn; D001921:Brain / Q000254:growth & development; D000076122:Disks Large Homolog 4 Protein; D004594:Electrophysiology; D018698:Glutamic Acid / Q000502:physiology*; D006801:Humans; D007231:Infant, Newborn; D047908:Intracellular Signaling Peptides and Proteins / Q000378:metabolism; D008565:Membrane Proteins / Q000378:metabolism; D051381:Rats; D018091:Receptors, AMPA / Q000187:drug effects / Q000502:physiology; D016194:Receptors, N-Methyl-D-Aspartate / Q000187:drug effects / Q000502:physiology; D012640:Seizures / Q000378:metabolism / Q000473:pathology*; D013569:Synapses / Q000378:metabolism / Q000473:pathology*
D000076122:Disks Large Homolog 4 Protein; C501449:Dlg4 protein, rat; D047908:Intracellular Signaling Peptides and Proteins; D008565:Membrane Proteins; D018091:Receptors, AMPA; D016194:Receptors, N-Methyl-D-Aspartate; D018698:Glutamic Acid