title: Progressive ORF virus infection in a patient with lymphoma: successful treatment using imiquimod.
abstract: Orf virus is a parapoxvirus that infects small ruminants worldwide. We present the case report of a 73-year-old woman with non-Hodgkins lymphoma who developed progressive orf virus lesions that were unresponsive to surgical debridement and to cidofovir therapy. The patient's orf virus infection was successfully treated with topical imiquimod despite progression of her malignancy.
authors.affiliation: Division of Viral and Rickettsial Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA. dvk9@cdc.gov
authors.forename: Edith R
authors.initials: ER
authors.lastname: Lederman
authors.forename: Gary M
authors.initials: GM
authors.lastname: Green
authors.forename: Henry E
authors.initials: HE
authors.lastname: DeGroot
authors.forename: Patricia
authors.initials: P
authors.lastname: Dahl
authors.forename: Erinn
authors.initials: E
authors.lastname: Goldman
authors.forename: Patricia W
authors.initials: PW
authors.lastname: Greer
authors.forename: Yu
authors.initials: Y
authors.lastname: Li
authors.forename: Hui
authors.initials: H
authors.lastname: Zhao
authors.forename: Christopher D
authors.initials: CD
authors.lastname: Paddock
authors.forename: Inger K
authors.initials: IK
authors.lastname: Damon
mesh_terms: D000276:Adjuvants, Immunologic / Q000627:therapeutic use*; D000368:Aged; D000634:Aminoquinolines / Q000627:therapeutic use*; D004474:Ecthyma, Contagious / Q000150:complications / Q000188:drug therapy* / Q000473:pathology; D005260:Female; D006801:Humans; D000077271:Imiquimod; D008228:Lymphoma, Non-Hodgkin / Q000150:complications*
chemical_list: D000276:Adjuvants, Immunologic; D000634:Aminoquinolines; D000077271:Imiquimod