title: Aspergillus oryzae peritonitis in CAPD: case report and review of the literature.
abstract: Fungal peritonitis is a rare, but serious, complication of continuous ambulatory peritoneal dialysis (CAPD). We report a case of peritonitis caused by Aspergillus oryzae in a man on CAPD therapy who was treated successfully with amphotericin B and caspofungin, followed by itraconazole and removal of the peritoneal catheter. A oryzae was identified by using sequence analysis of the ribosomal DNA genes. Of 10 reported cases since 2003, the mortality rate was 30%. Removal of the CAPD catheter and systemic antimycotic therapy are essential to achieve clinical cure in patients with fungal CAPD-related peritonitis.
authors.affiliation: Department of Pulmonology, Division of Infectious Diseases, Medical University of Graz, Austria.
authors.forename: Ines
authors.initials: I
authors.lastname: Schwetz
authors.forename: Jörg
authors.initials: J
authors.lastname: Horina
authors.forename: Walter
authors.initials: W
authors.lastname: Buzina
authors.forename: Johannes
authors.initials: J
authors.lastname: Roob
authors.forename: Horst
authors.initials: H
authors.lastname: Olschewski
authors.forename: Robert
authors.initials: R
authors.lastname: Krause
mesh_terms: D000368:Aged; D000935:Antifungal Agents / Q000627:therapeutic use; D001228:Aspergillosis / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology; D001236:Aspergillus oryzae / Q000187:drug effects / Q000235:genetics / Q000254:growth & development / Q000302:isolation & purification*; D006801:Humans; D008297:Male; D010531:Peritoneal Dialysis, Continuous Ambulatory / Q000009:adverse effects*; D010538:Peritonitis / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology*
chemical_list: D000935:Antifungal Agents