title: [Bronchial asthma attack with lactic acidosis and hypokalemia in a case receiving high dose inhalation of procaterol hydrochloride].
abstract: We report a case of bronchial asthma attack with lactic acidosis and hypokalemia in a patient receiving high-dose inhalation of procaterol hydrochloride. A 28-year-old man was transferred to our hospital because of adynamia, nausea and dyspnea. He had used inhaled procaterol hydrochloride with a pressurized metered dose inhaler about 20 times before admission. On admission, there were no signs of shock state or hypoxemia and laboratory data showed hypokalemia, hyperglycemia and metabolic acidosis with elevated anion gap. Lactic acidosis was identified as the reason for the metabolic acidosis with elevated anion gap. Lactic acidosis improved after 12 hours. Lactic acidosis due to high dose inhalation of procaterol hydrochloride was suggested.
authors.affiliation: Division of Respiratory Medicine, Respirology and Stress Care Center, Kagoshima University Hospital.
authors.forename: Satoshi
authors.initials: S
authors.lastname: Noma
authors.forename: Shingo
authors.initials: S
authors.lastname: Kubota
authors.forename: Kazuya
authors.initials: K
authors.lastname: Matsukizono
authors.forename: Asako
authors.initials: A
authors.lastname: Tanoue
authors.forename: Tomohiro
authors.initials: T
authors.lastname: Kumamoto
authors.forename: Tetsuhiko
authors.initials: T
authors.lastname: Taira
authors.forename: Hideo
authors.initials: H
authors.lastname: Mitsuyama
authors.forename: Toshihumi
authors.initials: T
authors.lastname: Kawabata
authors.forename: Takayuki
authors.initials: T
authors.lastname: Suetsugu
authors.forename: Jun
authors.initials: J
authors.lastname: Iwakaw
authors.forename: Yoshimizu
authors.initials: Y
authors.lastname: Koreed
authors.forename: Wataru
authors.initials: W
authors.lastname: Matsuyama
authors.forename: Keiko
authors.initials: K
authors.lastname: Mizuno
authors.forename: Ikkou
authors.initials: I
authors.lastname: Higashimoto
authors.forename: Mitsuhiro
authors.initials: M
authors.lastname: Osame
authors.forename: Kimiyoshi
authors.initials: K
authors.lastname: Arimura
mesh_terms: D000140:Acidosis, Lactic / Q000139:chemically induced*; D000280:Administration, Inhalation; D000318:Adrenergic beta-Agonists / Q000008:administration & dosage / Q000009:adverse effects*; D000328:Adult; D001249:Asthma / Q000188:drug therapy*; D006801:Humans; D007008:Hypokalemia / Q000139:chemically induced*; D008297:Male; D017265:Procaterol / Q000008:administration & dosage / Q000009:adverse effects*
chemical_list: D000318:Adrenergic beta-Agonists; D017265:Procaterol