Hermaphroditism in a Sprague-Dawley rat.
A spontaneous case of unilateral true hermaphroditism was observed during the routine necropsy of a 9-week-old presumed female Sprague-Dawley rat on a repeat-dose toxicity study. There were no drug-related effects observed. True hermaphroditism is rare in rats, and despite the large numbers of rats examined annually, few cases are reported in the literature.
Diters
R W
RW
Bristol-Myers Squibb Company, PO Box 4755, Syracuse, NY 13221, USA. richard.diters@bms.com
Funk
K A
KA
Fang
H
H
Durham
S K
SK
Mense
M G
MG
D000818:Animals; D005260:Female; D050090:Ovotesticular Disorders of Sex Development / Q000175:diagnosis / Q000473:pathology / Q000662:veterinary*; D051381:Rats; D017207:Rats, Sprague-Dawley; D012376:Rodent Diseases / Q000175:diagnosis / Q000473:pathology*