Localization of the structural genes for hexokinase-1 and inorganic pyrophosphatase on region (pter-->q24) of human chromosome 10.
Concordant expression of human hexokinase-1 and inorganic pyrophosphatase was established in somatic cell hybrids between thymidine kinase-deficient Chinese hamster cells and human fibroblasts carrying a translocation of the distal third of the long arm of chromosome 10 to chromosome 17. Neither human hexokinase-1 nor human inorganic pyrophosphatase expression segregated concordantly with human cytoplasmic glutamic-oxaloacetic transaminase expression.
Chern
C J
CJ
The Wistar Institute of Anatomy and Biology, Philadelphia, PA 19104, USA.
D000818:Animals; D001219:Aspartate Aminotransferases / Q000235:genetics; D002478:Cells, Cultured; D002874:Chromosome Mapping; D020090:Chromosome Segregation; D002879:Chromosomes, Human, Pair 10; D002886:Chromosomes, Human, Pair 17; D006224:Cricetinae; D003412:Cricetulus; D006593:Hexokinase / Q000235:genetics*; D006801:Humans; D006822:Hybrid Cells; D043564:Inorganic Pyrophosphatase / Q000235:genetics*; D014178:Translocation, Genetic
D001219:Aspartate Aminotransferases; C472074:HK1 protein, human; D006593:Hexokinase; D043564:Inorganic Pyrophosphatase