title: Leucine-rich repeat proteins of synapses.
abstract: Leucine-rich repeats (LRRs) are 20-29-aa motifs that mediate protein-protein interactions and are present in a variety of membrane and cytoplasmic proteins. Many LRR proteins with neuronal functions have been reported. Here, we summarize an emerging group of synaptic LRR proteins, which includes densin-180, Erbin, NGL, SALM, and LGI1. These proteins have been implicated in the formation, differentiation, maintenance, and plasticity of neuronal synapses.
authors.affiliation: National Creative Research Initiative Center for Synaptogenesis and Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Yuseong-Ku, Kuseong-Dong, Daejeon, Korea.
authors.forename: Jaewon
authors.initials: J
authors.lastname: Ko
authors.forename: Eunjoon
authors.initials: E
authors.lastname: Kim
mesh_terms: D000818:Animals; D000090263:Leucine-Rich Repeat Proteins; D011506:Proteins / Q000378:metabolism*; D013569:Synapses / Q000502:physiology*
chemical_list: D000090263:Leucine-Rich Repeat Proteins; D011506:Proteins