Community-acquired methicillin-resistant Staphylococcus aureus carrying Panton-Valentine leukocidin genes: a lethal cause of pneumonia in an adult immunocompetent patient.
Necrotizing pneumonia and fatal septic shock were caused by Panton-Valentine leukocidin-positive, community-acquired, methicillin-resistant Staphylococcus aureus (CA-MRSA) in a previously healthy, 61-y-old female. This patient did not belong to any high-risk group (e.g. homosexuals, military recruits, sports team members, etc.). CA-MRSA infection should be suspected in any adult with severe pneumonia/sepsis.
Magira
Eleni E
EE
Department of Intensive Care Medicine, University of Athens Medical School, Evaggelismos General Hospital, Athens, Greece. elmagira@yahoo.com
Zervakis
Dimitrios
D
Routsi
Christina
C
Kontogiorgi
Marina
M
Roussos
Charis
C
Nanas
Serafim
S
Mentzelopoulos
Spyros
S
D001427:Bacterial Toxins / Q000235:genetics*; D017714:Community-Acquired Infections / Q000382:microbiology; D005098:Exotoxins / Q000235:genetics*; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007121:Immunocompetence; D007956:Leukocidins / Q000235:genetics*; D016106:Methicillin Resistance / Q000187:drug effects*; D008875:Middle Aged; D009336:Necrosis; D018410:Pneumonia, Bacterial / Q000382:microbiology*; D012772:Shock, Septic / Q000382:microbiology*; D013203:Staphylococcal Infections / Q000150:complications* / Q000188:drug therapy; D013211:Staphylococcus aureus / Q000187:drug effects / Q000235:genetics / Q000472:pathogenicity*
D001427:Bacterial Toxins; D005098:Exotoxins; D007956:Leukocidins; C078284:Panton-Valentine leukocidin