A practical synthesis of 2,4(5)-diarylimidazoles from simple building blocks.
A simple and efficient approach to selectively obtain 2,4(5)-diarylimidazoles suppressing formation of 2-aroyl-4(5)-arylimidazoles is described. The yield of each of the two products strongly depends on the reaction conditions employed. This reaction provides a simple method to prepare small libraries of biologically active compounds by parallel synthesis.
Zuliani
Valentina
V
Dipartimento Farmaceutico, UniversitA degli Studi di Parma, V. le G.P. Usberti, 27/A, I-43100 Parma, Italy.
Cocconcelli
Giuseppe
G
Fantini
Marco
M
Ghiron
Chiara
C
Rivara
Mirko
M
D001555:Benzene Derivatives / Q000138:chemical synthesis*; D007093:Imidazoles / Q000138:chemical synthesis*
D001555:Benzene Derivatives; D007093:Imidazoles