title: Training or EPT in perimenopause on balance and flushes.
abstract: With advancing age, the postural balance function deteriorates as a consequence of decreased functional capacity. Deteriorating balance is a risk factor for bone fractures due to increased risks of falls. It has been suggested that the loss of estrogen, which occurs in relation to the menopause, may be associated with loss of balance. Regular physical exercise without balance training has, in some studies, been shown to have positive effects on the postural balance. The aim of the present study was to examine balance function during the perimenopausal period, and evaluate the effect of estrogen plus progesterone therapy (EPT) or aerobic training on balance. Sixty perimenopausal women were recruited to the study. The subjects were then randomised to either physical training (n=20), EPT (n=20), or to a control group (n=20). The study period was 18 months. Postural stability was measured every third month using a custom-made force platform. The women using EPT achieved better results in 3 of 6 parameters, after 18 months.
authors.affiliation: Center for Endocrinology, Metabolism and Diabetes, Karolinska Institutet at Karolinska University Hospital, Huddinge, Stockholm, Sweden. ingrid.b.bergstrom@karolinska.se
authors.forename: Ingrid
authors.initials: I
authors.lastname: Bergström
authors.forename: Britt-Marie
authors.initials: BM
authors.lastname: Landgren
authors.forename: Illmari
authors.initials: I
authors.lastname: Pyykkö
mesh_terms: D000058:Accidental Falls / Q000517:prevention & control; D000328:Adult; D000375:Aging / Q000502:physiology; D015914:Estrogen Replacement Therapy; D004967:Estrogens / Q000008:administration & dosage / Q000097:blood*; D015444:Exercise / Q000502:physiology*; D005260:Female; D019584:Hot Flashes / Q000188:drug therapy / Q000453:epidemiology; D006801:Humans; D008137:Longitudinal Studies; D008875:Middle Aged; D047648:Perimenopause / Q000097:blood / Q000187:drug effects / Q000502:physiology; D004856:Postural Balance / Q000187:drug effects / Q000502:physiology*; D011187:Posture; D011374:Progesterone / Q000008:administration & dosage / Q000097:blood*; D013546:Sweating / Q000187:drug effects
chemical_list: D004967:Estrogens; D011374:Progesterone