title: [Pharmacological mechanisms of Doxorubicin activity (DOX) - current state of knowledge].
abstract: Doxorubicin (DOX) belongs to the anthracycline antibiotics, widely used in the treatment of various types of malignancies. This review presents recent data about mechanisms of the drug action.
authors.affiliation: Katedra Termobiologii, Instytut Biofizyki, Uniwersytet Łódzki.
authors.forename: Dorota
authors.initials: D
authors.lastname: Łubgan
authors.forename: Agnieszka
authors.initials: A
authors.lastname: Marczak
authors.forename: Mateusz
authors.initials: M
authors.lastname: Walczak
authors.forename: Luitpold
authors.initials: L
authors.lastname: Distel
authors.forename: Zofia
authors.initials: Z
authors.lastname: Jóźwiak
mesh_terms: D000818:Animals; D000903:Antibiotics, Antineoplastic / Q000494:pharmacology*; D017209:Apoptosis / Q000187:drug effects*; D002467:Cell Nucleus / Q000187:drug effects; D004260:DNA Repair; D004317:Doxorubicin / Q000494:pharmacology*; D006801:Humans; D015394:Molecular Structure; D017382:Reactive Oxygen Species / Q000378:metabolism; D014407:Tumor Cells, Cultured / Q000187:drug effects*
chemical_list: D000903:Antibiotics, Antineoplastic; D017382:Reactive Oxygen Species; D004317:Doxorubicin