title: Isolated systolic hypertension in an elderly Danish population. Prevalence and daytime ambulatory blood pressure.
abstract: Isolated systolic hypertension (ISH) is a major risk factor for cardiovascular complications. Nevertheless, data on the prevalence in a representative population do not seem to be available. The prevalence of ISH and the white coat effect was thus studied in a cross-sectional survey of 2806 inhabitants aged 70-80 years. In untreated subjects, the prevalence of ISH was 17.4% (95% CI 14.9-20.2) in women and 13.5% (95% CI 11.3-15.9) in men using clinic blood pressure at first visit. The prevalence increased significantly with age. The prevalence was reduced to 10.4% when using the average of all-visits clinic blood pressures. By a simulation model, it was demonstrated that his reduction mainly resulted from a regression towards the mean. Average all-visits clinic blood pressure was 172.6 +/- 10.4/81.1 +/- 6.0 mmHg. Less than one-third of those with all-visit ISH had sustained ISH. Identifying subjects with sustained ISH requires measurements in more than three visits.
authors.affiliation: Holbaek, University of Copenhagen, Denmark. talleruphuus@dadlnet.dk
authors.forename: Ulrik
authors.initials: U
authors.lastname: Talleruphuus
authors.forename: Lia Evi
authors.initials: LE
authors.lastname: Bang
authors.forename: Niels
authors.initials: N
authors.lastname: Wiinberg
authors.forename: Jesper
authors.initials: J
authors.lastname: Mehlsen
authors.forename: Tage Lysbo
authors.initials: TL
authors.lastname: Svendsen
authors.forename: Michael Weis
authors.initials: MW
authors.lastname: Bentzon
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D018660:Blood Pressure Monitoring, Ambulatory / Q000706:statistics & numerical data*; D002940:Circadian Rhythm; D015331:Cohort Studies; D003198:Computer Simulation; D003718:Denmark / Q000453:epidemiology; D003971:Diastole; D005260:Female; D006801:Humans; D006973:Hypertension / Q000453:epidemiology*; D008297:Male; D008955:Models, Cardiovascular; D015995:Prevalence; D012424:Rural Population; D012494:Sampling Studies; D013599:Systole; D014505:Urban Population