title: Troponin repercussion of defibrillation at the end of cardiopulmonary bypass.
abstract: OBJECTIVE
  Cardiopulmonary bypass (CPB) is a relatively common procedure in cardiac surgery. At the end, the heart is electrically defibrillated if not already beating. External and internal cardioversion by specific catheters do not raise plasma troponin concentration, but the possible repercussion on troponin of the direct cardioversion of the heart has not been documented.
  
  
  METHODS
  Prospective comparative trial in a surgical intensive care unit in a university hospital was conducted. The study sample comprised 364 consecutive patients undergoing cardiac surgery with CPB and without perioperative myocardial infarction.
  
  
  RESULTS
  The number of cardioversions applied was recorded and three groups were obtained: A/no cardioversion; B/one or two cardioversions; and C/more than two cardioversions. Serum troponin I and CK-MB were determined at admission and after 6, 12, 24, and 48 hours. Significant differences were found between group C and groups A and B for troponin I and creatine kinase (CK-MB) curves, being higher for both variables in group C.
  
  
  CONCLUSIONS
  With more than two cardioversions post-CPB, both troponin I and CK-MB may present an additional increase.
authors.affiliation: Department of Intensive Care, Hospital Universitari de Bellvitge, Barcelona, Spain. 28136drc@comb.es
authors.forename: David
authors.initials: D
authors.lastname: Rodriguez-Castro
authors.forename: Elisabet
authors.initials: E
authors.lastname: Farrero
authors.forename: Casimiro
authors.initials: C
authors.lastname: Javierre
authors.forename: Maria L
authors.initials: ML
authors.lastname: Carrio
authors.forename: Antonio
authors.initials: A
authors.lastname: Diaz-Prieto
authors.forename: Jose
authors.initials: J
authors.lastname: Valero
authors.forename: Carles
authors.initials: C
authors.lastname: Fontanillas
authors.forename: Eduard
authors.initials: E
authors.lastname: Castells
authors.forename: Josep L
authors.initials: JL
authors.lastname: Ventura
mesh_terms: D000368:Aged; D002315:Cardiopulmonary Bypass; D052279:Creatine Kinase, MB Form / Q000097:blood*; D004554:Electric Countershock; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000097:blood / Q000175:diagnosis; D011446:Prospective Studies; D019210:Troponin I / Q000097:blood*
chemical_list: D019210:Troponin I; D052279:Creatine Kinase, MB Form