title: Plasma electrophoretogram in feline immunodeficiency virus (FIV) and/or feline leukaemia virus (FeLV) infections.
abstract: The electrophoretogram of 89 cats, including those infected by feline immunodeficiency virus (FIV+), feline leukaemia virus (FeLV+) and non-infected, showed statistically significant differences in several of the fractions. FIV+ cats had very high protein values (mean, 8.10 g/dl), mostly because of hypergammaglobulinemia (mean, 2.81 g/dl) as compared with non-infected animals and FeLV+. In addition, in these FIV+ animals, the albumin/globulins ratio (A/G) was very low (mean, 0.72). Statistically significant differences in A/G and alpha2-globulin fraction were observed in FeLV+ group (A/G mean, 0.88 +/- 0.08; alpha2-globulin, mean, 0.84 +/- 0.07 g/dl) when compared with non-infected group (A/G mean, 1.06 +/- 0.08; alpha2-globulin mean, 0.68 +/- 0.04 g/dl). The alpha1-globulin fraction was higher in double infected animals (FIV and FeLV positive, F-F) (3.55 g/dl), than in FeLV+ or FIV+ cats (3.10 and 3.07 g/dl respectively), but no statistical conclusions may be drawn from this fact because of the low number of F-F animals. This technique may help to assess the initial clinical status of retrovirus-infected cats, and the clinical course of these chronic diseases, specifically during and after suitable therapy.
authors.affiliation: Departamento de Sanidad Animal, Facultad de Veterinaria, Universidad Complutense, Madrid, Spain.
authors.forename: G
authors.initials: G
authors.lastname: Miró
authors.forename: A
authors.initials: A
authors.lastname: Doménech
authors.forename: E
authors.initials: E
authors.lastname: Escolar
authors.forename: V M
authors.initials: VM
authors.lastname: Collado
authors.forename: G
authors.initials: G
authors.lastname: Tejerizo
authors.forename: A
authors.initials: A
authors.lastname: De Las Heras
authors.forename: E
authors.initials: E
authors.lastname: Gómez-Lucía
mesh_terms: D000818:Animals; D015415:Biomarkers / Q000097:blood; D001797:Blood Protein Electrophoresis / Q000379:methods / Q000592:standards / Q000662:veterinary*; D016022:Case-Control Studies; D002415:Cats; D003937:Diagnosis, Differential; D016181:Feline Acquired Immunodeficiency Syndrome / Q000097:blood*; D005260:Female; D016089:Immunodeficiency Virus, Feline; D005256:Leukemia Virus, Feline; D016582:Leukemia, Feline / Q000097:blood*; D008297:Male; D012016:Reference Values
chemical_list: D015415:Biomarkers