Magnetic resonance spectroscopy as a diagnostic modality for carcinoma thyroid.
OBJECTIVE
The aim of this study was to observe the findings of magnetic resonance spectroscopy of solitary thyroid nodules and its correlation with histopathology.


METHODS
In this study, magnetic resonance spectroscopy was carried out on 26 patients having solitary thyroid nodules. Magnetic resonance spectroscopy (MRS) was performed on a 1.5T super conductive system with gradient strength of 33mTs. Fine needle aspiration cytology was done after MRS. All 26 patients underwent surgery either because of cytopathologically proven malignancy or because of cosmetic reasons. Findings of magnetic resonance spectroscopy were compared with histopathology of thyroid specimens.


CONCLUSIONS
It was seen that presence or absence of choline peak correlates very well with presence or absence of malignant foci with in the nodule (sensitivity=100%; specificity=88.88%). These results indicate that magnetic resonance spectroscopy may prove to be an useful diagnostic modality for carcinoma thyroid.
Gupta
Nikhil
N
Department of Surgery, Maulana Azad Medical College, Lok Nayak Hospital, New Delhi, India. nikhil_ms26@yahoo.co.in
Kakar
Arun K
AK
Chowdhury
Veena
V
Gulati
Praveen
P
Shankar
L Ravi
LR
Vindal
Anubhav
A
D018263:Adenocarcinoma, Follicular / Q000175:diagnosis / Q000473:pathology; D002288:Adenocarcinoma, Mucinous / Q000175:diagnosis / Q000473:pathology; D000236:Adenoma / Q000175:diagnosis / Q000473:pathology; D000293:Adolescent; D000328:Adult; D044963:Biopsy, Fine-Needle; D002277:Carcinoma / Q000175:diagnosis* / Q000473:pathology; D002291:Carcinoma, Papillary / Q000175:diagnosis / Q000473:pathology; D002648:Child; D002794:Choline / Q000032:analysis; D003560:Cysts / Q000175:diagnosis / Q000473:pathology; D005260:Female; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D008875:Middle Aged; D012680:Sensitivity and Specificity; D013959:Thyroid Diseases / Q000175:diagnosis / Q000473:pathology; D013964:Thyroid Neoplasms / Q000175:diagnosis* / Q000473:pathology; D016606:Thyroid Nodule / Q000175:diagnosis* / Q000473:pathology; D013967:Thyroiditis, Autoimmune / Q000175:diagnosis / Q000473:pathology
D002794:Choline