Steroidal glycosides from Hoodia gordonii.
Ten new C21-steroidal derivatives, namely gordonosides A-L (1-10) were isolated from a chloroform extract of the aerial parts of Hoodia gordonii, a plant widely used in the nutraceutical market as an ingredient of weight loss supplements. Compounds (2-10) are based on 3beta,14beta-dihydroxy-pregn-5-en-17-betaone aglycone (1). Their structures were characterized on the basis of HR-MS spectrometry and both 1D and 2D NMR techniques.
Dall'Acqua
Stefano
S
Department of Pharmaceutical Sciences, University of Padova, Via F. Marzolo 5, 35131 Padova, Italy.
Innocenti
Gabbriella
G
D029062:Apocynaceae / Q000737:chemistry*; D002851:Chromatography, High Pressure Liquid; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification*; D009682:Magnetic Resonance Spectroscopy
D006027:Glycosides