title: The palladium-catalyzed addition of aryl- and heteroarylboronic acids to aldehydes.
abstract: Reaction of aryl- or heteroarylboronic acids with aldehydes, in the presence of PdCl2 and P(1-Nap)3, afforded carbinol derivatives in good to excellent yields. The efficiency of this reaction was demonstrated by the compatibility with nitro, cyano, acetamido, acetoxy, acetyl, carboxyl, trifluoromethyl, fluoro, and chloro groups and the possibility of involving aliphatic aldehyde or hindered substrates. Moreover, the rigorous exclusion of air/moisture is not required in these transformations.
authors.affiliation: College of Chemistry and Materials Engineering, Wenzhou University, Wenzhou 325027, People's Republic of China.
authors.forename: Changming
authors.initials: C
authors.lastname: Qin
authors.forename: Huayue
authors.initials: H
authors.lastname: Wu
authors.forename: Jiang
authors.initials: J
authors.lastname: Cheng
authors.forename: Xi'an
authors.initials: X
authors.lastname: Chen
authors.forename: Miaochang
authors.initials: M
authors.lastname: Liu
authors.forename: Weiwei
authors.initials: W
authors.lastname: Zhang
authors.forename: Weike
authors.initials: W
authors.lastname: Su
authors.forename: Jinchang
authors.initials: J
authors.lastname: Ding