The radiological manifestations of sickle cell disease.
Sickle cell disease (SCD) is an inherited abnormality of the beta-globin chain, which causes a spectrum of haemolytic anaemias. Clinical manifestations in SCD include anaemia, jaundice, recurrent vaso-occlusive crises, and infections (particularly by encapsulated bacteria) due to functional asplenia and cerebrovascular accidents. Radiological investigations play a critical role both in the diagnosis and in the primary prevention of the complications of SCD.
Madani
G
G
Department of Radiology, Royal Free Hospital NHS Trust, London, UK. gittamadani@yahoo.com
Papadopoulou
A M
AM
Holloway
B
B
Robins
A
A
Davis
J
J
Murray
D
D
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