Management of highly sensitized patients--deceased donor.
The article reviews recent advances in management of highly sensitized patients. Possessing allo-antibodies leads to limited access to organs and increased risk of acute humoral rejection. Administration of IVIG decreased anti-HLA titers and seems efficient and safe desensitization approach.
Durlik
Magdalena
M
Department of Transplantation Medicine and Nephrology, Transplantation Institute, The Warsaw Medical University, Warsaw, Poland. mdurlik@am.edu.pl
D002102:Cadaver; D006085:Graft Survival; D006650:Histocompatibility Testing; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use; D007155:Immunologic Factors / Q000627:therapeutic use; D007518:Isoantibodies / Q000276:immunology; D016030:Kidney Transplantation / Q000276:immunology*; D012042:Registries; D012189:Retrospective Studies; D014019:Tissue Donors; D014181:Transplantation Immunology; D014184:Transplantation, Homologous / Q000276:immunology*
D016756:Immunoglobulins, Intravenous; D007155:Immunologic Factors; D007518:Isoantibodies