Application of correlation techniques in the analysis of corpus cavernosum electromyographic signals.
OBJECTIVE
To establish an objective, easy-to-use and comprehensive method to analyze corpus cavernosum electromyographic signals (CC-potentials).


METHODS
CC-potentials were recorded during flaccidity in 23 young healthy volunteers, with surface electrodes placed on the penile shaft bilaterally. Based on the correlation function of Matlab software, an application program for the analysis of CC-potentials was developed. Individual CC-potentials and their autocorrelation function were evaluated, yielding parameters amplitude (A), duration (D), and dominant frequency (DF). The cross-correlation function of both longitudinal and bilateral pairs of adjacent electrodes was calculated to assess the similarity and mutual delay of CC-potentials recorded simultaneously from different parts of the CC. The parameters derived were squared maximum cross-correlation coefficient (Rmax) and delay (tau). Based on the absolute value of tau and the corresponding inter-electrode distance, propagation velocity (PV) was calculated.


RESULTS
The values of the parameters were determined automatically. No significant difference related to the locations of the electrodes for parameters A, D, and DF was detected. The cross-correlation showed that both longitudinal and bilateral CC-potential pairs had highly similar waveforms (the absolute values of Rmax were 0.80 +/- 0.05 and 0.87 +/- 0.06, respectively). PV of longitudinal pairs was estimated as 6.15 +/- 3.98 cm/s.


CONCLUSIONS
The application program for correlation analysis of CC-potentials is a comprehensive and versatile method to analyze corpus cavernosum electromyographic recordings. Its objectiveness makes multi-center application possible.
Jiang
Xiao-Gang
XG
Department of Urology, Radboud University Nijmegen Medical Centre, 6500 HB Nijmegen, the Netherlands.
Holsheimer
Jan
J
Manola
Ljubomir
L
Wagner
Gorm
G
Wijkstra
Hessel
H
Knipscheer
Ben
B
Meuleman
Eric J H
EJ
D004576:Electromyography / Q000379:methods; D007172:Erectile Dysfunction / Q000175:diagnosis / Q000503:physiopathology; D006801:Humans; D008297:Male; D009130:Muscle, Smooth / Q000502:physiology*; D010413:Penis / Q000502:physiology*; D013223:Statistics as Topic / Q000379:methods*; D013564:Sympathetic Nervous System / Q000502:physiology