title: [Evaluation of blood and breath alcohol measurement in patients with hepatocellular carcinoma during procedures in intubated patients with percutaneous ethanol instillation].
abstract: The accuracy of breath alcohol measurements in intubated patients with assisted ventilation was evaluated. The breath alcohol concentration was measured in 24 patients undergoing percutaneous alcohol injection therapy for hepatocellular carcinoma with Alcotest 7410 med, from Dräger, Germany. The blood ethanol concentrations (BACs) were determined in each blood serum applying the German forensic criteria standard, namely, two alcohol dehydrogenase (ADH) and two gas chromatography (GC) measurements. The blood alcohol concentrations were between 0.07 and 1.51 per thousand in the central venous samples and 0.02-1.66 per thousand in the arterial samples. An excellent correlation between both the venous and arterial blood alcohol concentrations (r2=0.94), as well as between the breath alcohol concentrations and the venous (r2=0.84) or arterial alcohol concentration (r2=0.89), p<0.01 for both parameters was revealed. Determination of breath alcohol concentration using the Alcotest in intubated patients is reliable and reflects the blood alcohol values.
authors.affiliation: St.Josef-Hospital Kloppenburg, Department of Anesthesiology, Germany.
authors.forename: C
authors.initials: C
authors.lastname: Weilbach
authors.forename: G
authors.initials: G
authors.lastname: Kedia
authors.forename: K
authors.initials: K
authors.lastname: Albrecht
authors.forename: J
authors.initials: J
authors.lastname: Heine
authors.forename: S
authors.initials: S
authors.lastname: Piepenbrock
authors.forename: U
authors.initials: U
authors.lastname: Jonas
authors.forename: D
authors.initials: D
authors.lastname: Breitmeier
mesh_terms: D000279:Administration, Cutaneous; D000368:Aged; D000435:Alcoholic Intoxication / Q000175:diagnosis*; D001944:Breath Tests; D006528:Carcinoma, Hepatocellular / Q000628:therapy*; D002492:Central Nervous System Depressants / Q000008:administration & dosage / Q000097:blood* / Q000627:therapeutic use*; D000431:Ethanol / Q000008:administration & dosage / Q000097:blood* / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007322:Instillation, Drug; D008113:Liver Neoplasms / Q000628:therapy*; D008297:Male; D012121:Respiration, Artificial
chemical_list: D002492:Central Nervous System Depressants; D000431:Ethanol