Retinopathy in a multiple sclerosis patient undergoing interferon-therapy.
A 30-year old male developed retinopathy, with flame-shaped retinal hemorrhages and soft exudates in both eyes, while receiving interferon-beta injections as a preventive therapy for multiple sclerosis (MS). After discontinuing interferon injections upon presentation of the retinopathy, the retinopathy subsided without specific therapy. Visual acuity remained stable throughout the course of observation. Though assumed to be related to interferon therapy, the ocular findings of retinopathy disappeared without specific treatment. This clinical course of retinopathy is very similar to the interferon-induced retinopathy observed in type C hepatitis patients, but there are far fewer reports on MS-related interferon retinopathy.
Saito
Hitomi
H
Department of Ophthalmology, University of Tokyo, Graduate School of Medicine, Tokyo, Japan. hitomi8678@yahoo.co.jp
Suzuki
Mariko
M
Asakawa
Takehiro
T
Kato
Satoshi
S
D000328:Adult; D006801:Humans; D007155:Immunologic Factors / Q000009:adverse effects*; D016899:Interferon-beta / Q000009:adverse effects*; D008297:Male; D009103:Multiple Sclerosis / Q000188:drug therapy*; D009887:Ophthalmoscopy; D012164:Retinal Diseases / Q000139:chemically induced* / Q000175:diagnosis
D007155:Immunologic Factors; D016899:Interferon-beta