Quality of life in dementia.
There is a growing consensus that quality of life (QOL) is an important outcome for assessing the effectiveness of interventions for dementia, but there is no agreement about how to best measure it. Various approaches to QOL assessment have been employed to measure the QOL of persons with dementia, including patient self-report, caregiver proxy report and observational assessment by trained observers. Furthermore, several dementia-specific measures of QOL have been developed, and several generic measures of QOL have been used to assess QOL in dementia. However, to date, QOL has rarely been included as an outcome measure in clinical trials of pharmacotherapy for dementia. This manuscript reviews the current state of knowledge about QOL assessment in dementia.
Naglie
Gary
G
Division of General Internal Medicine, University Health Network, Canada.
D017028:Caregivers / Q000592:standards; D002986:Clinical Trials as Topic / Q000379:methods* / Q000592:standards; D003704:Dementia / Q000175:diagnosis* / Q000523:psychology*; D004185:Disability Evaluation; D006801:Humans; D009483:Neuropsychological Tests / Q000592:standards*; D010043:Outcome and Process Assessment, Health Care / Q000379:methods* / Q000592:standards; D011237:Predictive Value of Tests; D011788:Quality of Life / Q000523:psychology*; D018434:Sickness Impact Profile; D016896:Treatment Outcome