[Selective karyotyping in repeated miscarriage].
Maternal age, history of miscarriage and family history relating to early pregnancy losses, are important risk factors for the development of new miscarriages. These factors may be considered in offering chromosome analysis to couples with > 3 miscarriages. Selective chromosome analysis would result in a more efficient care. However, the way to implement selective chromosome analysis remains a subject for debate.
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Universitair Medisch Centrum St Radboud, afd. Verloskunde en Gynacologie, Postbus 9101, 6500 HB Nijmegen. w.nelen@obgyn.umcn.nl
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D000026:Abortion, Habitual / Q000235:genetics*; D000328:Adult; D002869:Chromosome Aberrations; D005260:Female; D020022:Genetic Predisposition to Disease; D005820:Genetic Testing; D006801:Humans; D007621:Karyotyping; D008297:Male; D008423:Maternal Age; D018579:Patient Selection; D011247:Pregnancy; D018570:Risk Assessment; D012307:Risk Factors