title: Analysis and evaluation of environmental tobacco smoke exposure as a risk factor for chronic cough.
abstract: Exposure to environmental tobacco smoke (ETS) and active tobacco smoking has been shown to increase symptoms of bronchial asthma such as bronchoconstriction but effects on other respiratory symptoms remain poorly assessed. Current levels of exposure to tobacco smoke may also be responsible for the development of chronic cough in both children and adults. The present study analyses the effects of tobacco smoke exposure as potential causes of chronic cough. A panel of PubMed-based searches was performed relating the symptom of cough to various forms of tobacco smoke exposure. It was found that especially prenatal and postnatal exposures to ETS have an important influence on children's respiratory health including the symptom of cough. These effects may be prevented if children and pregnant women are protected from exposure to ETS. Whereas the total number of studies addressing the relationship between cough and ETS exposure is relatively small, the present study demonstrated that there is a critical amount of data pointing to a causative role of environmental ETS exposure for the respiratory symptom of cough. Since research efforts have only targeted this effect to a minor extent, future epidemiological and experimental studies are needed to further unravel the relation between ETS and cough.
authors.affiliation: Division of Allergy Research, Charité-Universitätsmedizin Berlin, Free University and Humboldt-University, D-13353 Berlin, Germany. beatrix.groneberg-kloft@charite.de
authors.forename: Beatrix
authors.initials: B
authors.lastname: Groneberg-Kloft
authors.forename: Wojciech
authors.initials: W
authors.lastname: Feleszko
authors.forename: Quoc Thai
authors.initials: QT
authors.lastname: Dinh
authors.forename: Anke
authors.initials: A
authors.lastname: van Mark
authors.forename: Elke
authors.initials: E
authors.lastname: Brinkmann
authors.forename: Dirk
authors.initials: D
authors.lastname: Pleimes
authors.forename: Axel
authors.initials: A
authors.lastname: Fischer