title: The hair collar sign as a marker for neural tube defects.
abstract: The hair collar sign has been described as a marker of cranial dysraphism, including encephaloceles, meningoceles, and heterotropic brain tissue. This report describes a male born with a hair collar sign who subsequently was found to have a Klippel-Feil anomaly, diastematomyelia, multiple segmental spine and rib anomalies, and a translocation between chromosomes 1 and 4; t(1;4) (q44;q10). While not previously documented, spine abnormalities may be an associated abnormality with the hair collar sign. Physicians should consider radiographic evaluation of the spine in all newborns with a hair collar sign, as well as genetic screening.
authors.affiliation: Southern Colorado Family Medicine Residency Program, St. Mary Corwin Medical Center, Pueblo, Colorado, USA. brilorharrington@comcast.net
authors.forename: Brian C
authors.initials: BC
authors.lastname: Harrington
mesh_terms: D006801:Humans; D007231:Infant, Newborn; D007714:Klippel-Feil Syndrome / Q000175:diagnosis* / Q000235:genetics; D008297:Male; D009436:Neural Tube Defects / Q000150:complications* / Q000235:genetics; D019339:Port-Wine Stain / Q000209:etiology*; D014178:Translocation, Genetic