[HPV vaccines. Prophylactic vaccines from virus-like particles].
The new prophylactic HPV vaccines consist of virus-like particles self-assembled from recombinantly expressed L1 major capsid protein. Due to the absence of potentially oncogenic viral DNA, they have been proven safe and well tolerated in thousands of vaccinated individuals. Prophylactic HPV vaccination has demonstrated 100% efficacy in preventing type-specific persistent infections and associated genital dysplasias.
Kirnbauer
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Abteilung für Immundermatologie und Infektiöse Hautkrankheiten, Klinik für Dermatologie, Medizinische Universität Wien, Währinger Gürtel 18-20, 1090, Wien, Osterreich. reinhard.kirnbauer@meduniwien.ac.at
D015195:Drug Design; D005260:Female; D006801:Humans; D007114:Immunization / Q000379:methods* / Q000639:trends; D030361:Papillomavirus Infections / Q000188:drug therapy / Q000517:prevention & control*; D053918:Papillomavirus Vaccines / Q000627:therapeutic use*; D017410:Practice Guidelines as Topic; D010818:Practice Patterns, Physicians' / Q000639:trends; D002583:Uterine Cervical Neoplasms / Q000188:drug therapy / Q000517:prevention & control*; D014771:Virion
D053918:Papillomavirus Vaccines