title: Mitomycin C and conjunctival autograft for recurrent pterygium.
abstract: OBJECTIVE
  To observe the efficiency of intraoperative low-dose Mitomycin-C combined with conjunctival autograft in the treatment of recurrent pterygium.
  
  
  METHODS
  Fifteen eyes with recurrent pterygium were included in this study. The mean age of the patients was 51.6 +/- 11.4 (9 men, 6 women). All patients underwent excision of the pterygium tissue and subconjunctival fibrous tissue with a no cautery approach. 0.2 mg/ml Mitomycin-C (0.02%) was applied for 3 min. Conjunctival autograft was obtained from the superotemporal bulbar conjunctiva of the same eye. Eyes were followed for a mean period of 21.0 +/- 9.1 months.
  
  
  RESULTS
  Recurrence was seen in two eyes (13.3%) during the follow-up period. The only complication seen was graft edema (two eyes; 13.3%) which healed after pressure patching. Graft necrosis, scleral melting or failure of revascularization was not noted.
  
  
  CONCLUSIONS
  Intraoperative application of 0.2 mg/ml Mitomycin-C combined with conjunctival autograft reduces recurrence in recurrent pterygium cases, with minimal complications.
authors.affiliation: Department of Ophthalmology, Ankara Training and Research Hospital, Ankara, Turkey. ealtiparmak@hotmail.com
authors.forename: Uğur E
authors.initials: UE
authors.lastname: Altiparmak
authors.forename: Yasemin Aslan
authors.initials: YA
authors.lastname: Katircioğlu
authors.forename: Ramazan
authors.initials: R
authors.lastname: Yağci
authors.forename: Züleyha
authors.initials: Z
authors.lastname: Yalniz
authors.forename: Sunay
authors.initials: S
authors.lastname: Duman
mesh_terms: D000328:Adult; D000368:Aged; D000477:Alkylating Agents / Q000008:administration & dosage*; D003131:Combined Modality Therapy; D003228:Conjunctiva / Q000637:transplantation*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D016685:Mitomycin / Q000008:administration & dosage*; D011625:Pterygium / Q000188:drug therapy* / Q000601:surgery*; D012008:Recurrence; D014182:Transplantation, Autologous
chemical_list: D000477:Alkylating Agents; D016685:Mitomycin