[Peritoneal mesothelium--the role in fibrin transformations].
Peritoneum is a serous membrane with a significant fibrinolytic potential, playing an important role in the abdominal response to trauma. Peritoneum takes part in the formation and degradation of postoperative adhesions. The sequence of changes during the adhesion formation is indispensable in the healing of peritoneal trauma. Presented paper describes the short historical update of mesothelial research and review of contemporary knowledge over the peritoneal function with special regard to its fibrinolytic activity. The factors influencing the fibrinolytic capacity of peritoneum were discussed, as well as present pathways of research on the prevention of postoperative adhesion formation.
Winckiewicz
Marek
M
Klinika Chirurgii Ogólnej i Naczyń II Katedry Chirurgii Akademii Medycznej im. Karola Marcinkowskiego w Poznaniu. marwin_pl@poczta.onet.pl
Staniszewski
Ryszard
R
Połubińska
Alicja
A
Breborowicz
Andrzej
A
D000818:Animals; D001202:Ascitic Fluid / Q000378:metabolism; D004848:Epithelium / Q000378:metabolism; D005337:Fibrin / Q000378:metabolism*; D005338:Fibrin Fibrinogen Degradation Products / Q000378:metabolism*; D005342:Fibrinolysis / Q000502:physiology*; D006801:Humans; D010537:Peritoneum / Q000503:physiopathology* / Q000601:surgery; D017395:Plasminogen Activator Inhibitor 1 / Q000378:metabolism; D011183:Postoperative Complications / Q000503:physiopathology / Q000517:prevention & control; D051381:Rats; D000267:Tissue Adhesions / Q000378:metabolism / Q000503:physiopathology* / Q000517:prevention & control; D010959:Tissue Plasminogen Activator / Q000378:metabolism*; D014945:Wound Healing / Q000502:physiology
D005338:Fibrin Fibrinogen Degradation Products; D017395:Plasminogen Activator Inhibitor 1; D005337:Fibrin; D010959:Tissue Plasminogen Activator