title: [Short-term fluoride release from conseal F fissure sealant in some media--an in vitro study].
abstract: BACKGROUND
  Low fluoride concentrations constantly maintained in the oral cavity are important for caries prevention. Application of fissure sealants containing fluoride improves protection and reinforces caries prophylaxis. The aim of this study was to assess the level of fluoride release from Conseal F fissure sealant in different media.
  
  
  METHODS
  Sealant samples were placed in (a) artificial saliva without calcium ions (C++) at pH of 4.5, 5.5, 6.0, 7.0, and 7.5, (b) artificial saliva with calcium ions (Ca") at pH 4.5, and 5.5, (c) saline, and (d) deionized water. Fluoride concentration in solution was measured after 1, 3, 24, 48, 72, and 168 hours from the start of the experiment.
  
  
  RESULTS
  The highest cumulative fluoride concentration was found in saline (9.39 +/- 2.17 microg F/mm(2)), the lowest in artificial saliva at pH of 7.0 (0.45+/-0.14 microg F/mm(2)). The highest fluoride emission was observed during the first three hours which then decreased to a low but relatively stable level.
  
  
  CONCLUSIONS
  The level of fluoride release from Conseal F fissure sealant depends on composition and pH of the medium. Decrease in pH increased fluoride release. This property is essential for patients with low salivary pH and high risk of caries.
authors.affiliation: Zaklad Propedeutyki Stomatologicznej Akademii Medycznej we Wrocławiu
authors.forename: Piotr
authors.initials: P
authors.lastname: Kosior
authors.forename: Urszula
authors.initials: U
authors.lastname: Kaczmarek
mesh_terms: D002118:Calcium / Q000737:chemistry; D002327:Cariostatic Agents / Q000737:chemistry; D020099:Coated Materials, Biocompatible; D005459:Fluorides / Q000032:analysis* / Q000737:chemistry; D006801:Humans; D006863:Hydrogen-Ion Concentration; D017736:Ion-Selective Electrodes; D008422:Materials Testing; D010895:Pit and Fissure Sealants / Q000032:analysis* / Q000737:chemistry*; D012464:Saliva, Artificial / Q000737:chemistry*; D013997:Time Factors
chemical_list: D002327:Cariostatic Agents; D020099:Coated Materials, Biocompatible; D010895:Pit and Fissure Sealants; D012464:Saliva, Artificial; D005459:Fluorides; D002118:Calcium