Laser-modified titanium implants for improved cell adhesion.
Concerning dental implant systems, a main problem is the adhesion of peri-implant mucosa in the cervical region. The aim of the present study was to use a laser for modifying titanium implants to promote mucosal adhesion, which is indispensable as a biological barrier against bacterial infection. By the use of a KrF excimer laser, it was possible to induce a holey structure on the polished area of the implant surface, which was analysed by a scanning electron microscope. In addition, the attachment of fibroblast cells to the created structures was investigated with the aid of an environmental scanning electron microscope. It turned out that the cells preferentially attach to the holey structure. Thereby, the cells form bridges inside, leading to a complete covering of the hole. In this way, a more effective biological barrier against bacteria can be created.
Heinrich
Andreas
A
Lehrstuhl für Experimentalphysik IV, Universität Augsburg, Universitätsstr. 1, 86135, Augsburg, Germany. Andreas.Heinrich@physik.uni-augsburg.de
Dengler
Katrin
K
Koerner
Timo
T
Haczek
Cornelia
C
Deppe
Herbert
H
Stritzker
Bernd
B
D002448:Cell Adhesion; D003758:Dental Implantation, Endosseous; D015921:Dental Implants; D006801:Humans; D007834:Lasers; D016348:Osseointegration; D011474:Prosthesis Design; D011829:Radiation Dosage; D013499:Surface Properties; D014025:Titanium
D015921:Dental Implants; D014025:Titanium