title: Seroprevalence of HIV infection in hospitalized paediatric patients at a tertiary care centre in western India.
abstract: The prevalence of HIV infection in children in India is not known. In this study, a total of 270 children admitted to paediatric wards in Mumbai were screened for HIV infection by enzyme-linked immunosorbent assay (ELISA). Eight patients (2.96%) had a positive HIV ELISA. Of these two patients (25%) were less than 15 months of old and hence HIV infection in them could not be confirmed. The prevalence of HIV was 2.3%. Three out of 11 patients with tuberculosis (27.3%) and four out of 15 patients with nutritional anaemia (26.7%) had HIV infection (P<0.0001 in each case). Vertical transmission was the cause in all children, suggesting that implementation of Prevention of Parent to Child Transmission of HIV (PPTCT) is required to reduce the rate of paediatric HIV infection.
authors.affiliation: Department of Pediatric HIV, B. J. Wadia Hospital for Children, Parel, Mumbai, India. irashah@pediatriconcall.com
authors.forename: I
authors.initials: I
authors.lastname: Shah
authors.forename: B
authors.initials: B
authors.lastname: Katira
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D003430:Cross-Sectional Studies; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006678:HIV / Q000302:isolation & purification*; D015483:HIV Antibodies / Q000097:blood*; D015658:HIV Infections / Q000453:epidemiology* / Q000635:transmission; D006679:HIV Seropositivity; D006801:Humans; D007194:India / Q000453:epidemiology; D007223:Infant; D018445:Infectious Disease Transmission, Vertical; D008297:Male; D010361:Patients; D016036:Seroepidemiologic Studies; D014505:Urban Population
chemical_list: D015483:HIV Antibodies