title: Pimelea trichostachya poisoning (St George disease) in horses.
abstract: A dense population of Pimelea trichostachya plants (Family Thymelaeaceae) in pasture poisoned a horse herd in southern inland Queensland in October-November 2005. Plant density was 2 to 45 g wet weight/m(2) (mean 16 g/m(2)) from 5 to 69 plants/m(2) (mean 38 plants/m(2)) representing 3 to 20% (mean 9%) of the volume of pasture on offer. Ten of 35 mares, fillies and geldings were affected. Clinical signs were loss of body weight, profound lethargy, serous nasal discharge, severe watery diarrhoea and subcutaneous oedema of the intermandibular space, chest and ventral midline. Pathological findings were anaemia, leucocytopenia, hypoproteinaemia, dilatation of the right ventricle of the heart, dilated hepatic portal veins and periportal hepatic sinusoids (peliosis hepatis), alimentary mucosal hyperaemia and oedema of mesenteric lymph nodes. Cattle grazing the same pasture were affected by Pimelea poisoning simultaneously. Removal of the horses to Pimelea-free pasture initiated recovery. The one other incident of this syndrome, previously only recognised in cattle in Australia, occurred in horses, in South Australia in 2002, with access to a dense Pimelea simplex population.
authors.affiliation: Department of Primary Industries and Fisheries, Queensland, Australia. sarah-jane.wilson@dpi.qld.gov.au
authors.forename: S-J
authors.initials: SJ
authors.lastname: Wilson
authors.forename: J  D
authors.initials: J
authors.lastname: Taylor
authors.forename: J  A
authors.initials: J
authors.lastname: Gibson
authors.forename: R  A
authors.initials: R
authors.lastname: McKenzie
mesh_terms: D000818:Animals; D001798:Blood Proteins / Q000032:analysis; D004196:Disease Outbreaks / Q000662:veterinary; D005260:Female; D006734:Horse Diseases / Q000097:blood / Q000453:epidemiology* / Q000473:pathology; D006736:Horses; D008297:Male; D010939:Plant Poisoning / Q000097:blood / Q000453:epidemiology / Q000473:pathology / Q000662:veterinary*; D011793:Queensland / Q000453:epidemiology; D015431:Weight Loss
chemical_list: D001798:Blood Proteins