New dammarane triterpenes from Maytenus macrocarpa.
Two new dammarane triterpenes have been isolated from the stem bark exudates of Maytenus macrocarpa. Their structures were determined by extensive 1D and 2D NMR spectroscopic studies as 24(Z)-3-oxodammara-20(21),24-dien-27-oic acid (1) and octa-nor-13-hydroxydammara-1-en-3,17-dione (2). These compounds were tested for antitumoral activity.
Torpocco
Virginia
V
Instituto Universitario de Bio-Orgánica Antonio González, Avda, Astrofísico Francisco Sánchez No2, La Laguna, 38206 Tenerife, Spain.
Chávez
Haydee
H
Estévez-Braun
Ana
A
Ravelo
Angel Gutiérrez
AG
D018744:DNA, Plant / Q000737:chemistry / Q000235:genetics; D009682:Magnetic Resonance Spectroscopy; D029755:Maytenus / Q000737:chemistry*; D012441:Saccharomyces cerevisiae / Q000378:metabolism; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet; D014315:Triterpenes / Q000737:chemistry* / Q000302:isolation & purification; D000097669:Dammaranes
D018744:DNA, Plant; D014315:Triterpenes; D000097669:Dammaranes; C520870:3-oxodammara-20(21),24-dien-27-oic acid; C520869:octa-nor-13-hydroxydammara-1-en-3,17-dione