title: Stimulation of the biosynthesis of the antibiotics lambertellols by the mycoparasitic fungus Lambertella corni-maris under the acidic conditions produced by its host fungus in vitro.
abstract: The filamentous fungus, Lambertella corni-maris (L. corni-maris), a mycoparasite on Monilinia fructigena, produces the antibiotics, lambertellols A (1), B (2), and lambertellin (3), in a substantial amounts under acidic conditions, whereas these antibiotics were hardly detected when the fungus was cultured on a potato-sucrose (PS) medium without added acids. Our investigations also revealed that the host, M. fructigena, changed its surroundings into acidic conditions, suggesting that the acidic conditions acted as kairomones that stimulated the production of 1-3.
authors.affiliation: Faculty of Agriculture and Life Science, Hirosaki University, Hirosaki, Japan.
authors.forename: Takanori
authors.initials: T
authors.lastname: Murakami
authors.forename: Noboru
authors.initials: N
authors.lastname: Takada
authors.forename: Yukio
authors.initials: Y
authors.lastname: Harada
authors.forename: Toshikatsu
authors.initials: T
authors.lastname: Okuno
authors.forename: Masaru
authors.initials: M
authors.lastname: Hashimoto
mesh_terms: D000900:Anti-Bacterial Agents / Q000096:biosynthesis*; D001203:Ascomycota / Q000737:chemistry* / Q000187:drug effects* / Q000502:physiology; D002851:Chromatography, High Pressure Liquid; D006790:Host-Parasite Interactions; D006863:Hydrogen-Ion Concentration; D066298:In Vitro Techniques; D015394:Molecular Structure; D009281:Naphthalenes / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology*; D013050:Spectrometry, Fluorescence; D013141:Spiro Compounds / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology*
chemical_list: D000900:Anti-Bacterial Agents; D009281:Naphthalenes; D013141:Spiro Compounds