title: Cerebellar cortical abiotrophy in Lagotto Romagnolo dogs.
abstract: This case report documents two pathological variations of potentially inherited, cerebellar cortical abiotrophy in two unrelated Lagotto Romagnolo breed dogs. The first dog had an atypical lesion in the cerebellar cortex with depletion of cerebellar granular cell layer and sparing of the Purkinje cell layer. The second case had degenerative changes in both Purkinje and granular cell layers. The clinical picture was similar in both cases presented, although the severity of the signs of cerebellar dysfunction varied.
authors.affiliation: Department of Clinical Veterinary Sciences, University of Helsinki, PO Box 57, 00014 Helsinki, Finland.
authors.forename: T S
authors.initials: TS
authors.lastname: Jokinen
authors.forename: C
authors.initials: C
authors.lastname: Rusbridge
authors.forename: F
authors.initials: F
authors.lastname: Steffen
authors.forename: R
authors.initials: R
authors.lastname: Viitmaa
authors.forename: P
authors.initials: P
authors.lastname: Syrjä
authors.forename: A
authors.initials: A
authors.lastname: De Lahunta
authors.forename: M
authors.initials: M
authors.lastname: Snellman
authors.forename: S
authors.initials: S
authors.lastname: Cizinauskas
mesh_terms: D000818:Animals; D001284:Atrophy / Q000473:pathology / Q000662:veterinary; D002526:Cerebellar Diseases / Q000175:diagnosis / Q000662:veterinary*; D003937:Diagnosis, Differential; D004283:Dog Diseases / Q000175:diagnosis* / Q000473:pathology; D004285:Dogs; D005260:Female; D009460:Neurologic Examination / Q000662:veterinary; D010375:Pedigree; D011689:Purkinje Cells / Q000473:pathology