title: Synthesis and characterization of a dehydrogenation product arising from the oxidation of aminoethylcysteine ketimine decarboxylated dimer.
abstract: While investigating the antioxidant properties of aminoethylcysteine ketimine decarboxylated dimer (1) (a natural substance occurring in biological fluids such as human urine and plasma and in bovine cerebellum), a previously unreported oxidation product was obtained. This compound was identified and characterized through comparison with an authentic sample prepared via Pd-catalyzed dehydrogenation of 1. This molecule is an example of an alternative oxidation pathway involving 1.
authors.affiliation: Department of Biochemical Sciences A. Rossi-Fanelli and National Research Council Institute of Molecular Biology and Pathology, University of Rome La Sapienza, Piazzale Aldo Moro 5, 00185 Rome, Italy.
authors.forename: Alberto
authors.initials: A
authors.lastname: Macone
authors.forename: Aldo
authors.initials: A
authors.lastname: Caiazzo
authors.forename: Antonio
authors.initials: A
authors.lastname: Antonucci
authors.forename: Igor
authors.initials: I
authors.lastname: Fochi
authors.forename: Mirella
authors.initials: M
authors.lastname: Nardini
authors.forename: Silvestro
authors.initials: S
authors.lastname: Duprè
authors.forename: Rosa Marina
authors.initials: RM
authors.lastname: Matarese
mesh_terms: D000818:Animals; D000975:Antioxidants / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D002417:Cattle; D002531:Cerebellum / Q000737:chemistry; D006801:Humans; D015394:Molecular Structure; D009025:Morpholines / Q000097:blood / Q000138:chemical synthesis* / Q000737:chemistry / Q000652:urine; D010084:Oxidation-Reduction; D010165:Palladium / Q000737:chemistry
chemical_list: C086349:5,9a-dihydro-5-oxopyrrolo(2,1-c-3,4-b')dithiomorpholine; D000975:Antioxidants; D009025:Morpholines; D010165:Palladium