The neural basis of processing anomalous information.
This study explored the neural basis of the processing of anomalous information (the N400 effect) in an arithmetic task. Twenty healthy undergraduate students were scanned while they performed a number-matching task. Relative to matched numbers, unmatched numbers elicited significantly greater activation at left inferior and superior parietal cortex, left inferior frontal gyrus, and left fusiform and lingual gyri. Combining these results and those of previous studies on semantic anomaly, we proposed that the parietal region is the source of the arithmetic N400 component and the left inferior frontal gyrus is involved in domain-general processing of anomalous information.
Chen
Chunhui
C
State Key Laboratory of Cognitive Neuroscience and Learning, Beijing Normal University, Beijing, China.
Zhou
Xinlin
X
Chen
Chuansheng
C
Dong
Qi
Q
Zang
Yufeng
Y
Qiao
Sibing
S
Yang
Tao
T
Gong
Qiyong
Q
D000293:Adolescent; D000328:Adult; D001931:Brain Mapping; D004569:Electroencephalography / Q000379:methods; D005071:Evoked Potentials / Q000502:physiology*; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D008433:Mathematics; D008606:Mental Processes / Q000502:physiology*; D009483:Neuropsychological Tests; D010100:Oxygen / Q000097:blood; D010296:Parietal Lobe / Q000098:blood supply / Q000502:physiology*; D011930:Reaction Time / Q000502:physiology
D010100:Oxygen