title: Caffey's disease: an unusual cause for concern.
abstract: BACKGROUND
  Caffey's disease or infantile cortical hyperostosis is a rare cause of irritability, bone pain, soft tissue swelling and fever in the infant.
  
  
  OBJECTIVE
  To review the presentation and diagnosis of an 8-week old infant with focal tenderness of the tibia.
  
  
  METHODS
  The symptoms, signs, laboratory work-up and radiology are reviewed.
  
  
  RESULTS
  The child presented with focal bony tenderness and pyrexia. Laboratory work-up was inconclusive. The diagnosis of Caffey's disease was made following a skeletal survey to outrule non-accidental injury, which showed similar changes of cortical thickening in the mandible as well as the affected tibia.
  
  
  CONCLUSIONS
  With our increasing immigrant population, an increasing number of differential diagnoses must be considered when evaluating patients presenting to our emergency rooms. Caffey's disease is an unusual cause of bone pain in the infant. Symptoms and signs are subtle and the diagnosis is generally made with plain X-rays.
authors.affiliation: Department of Orthopaedic Surgery, Our Ladys' Hospital for Sick Children, Crumlin, Dublin 12, Ireland. fjshannon@gmail.com
authors.forename: F J
authors.initials: FJ
authors.lastname: Shannon
authors.forename: M
authors.initials: M
authors.lastname: Murphy
authors.forename: I
authors.initials: I
authors.lastname: Atchia
authors.forename: E
authors.initials: E
authors.lastname: Phelan
authors.forename: E E
authors.initials: EE
authors.lastname: Fogarty
mesh_terms: D005260:Female; D006801:Humans; D006811:Humerus / Q000000981:diagnostic imaging; D006958:Hyperostosis, Cortical, Congenital / Q000175:diagnosis* / Q000000981:diagnostic imaging; D007223:Infant; D008336:Mandibular Diseases / Q000175:diagnosis; D011859:Radiography; D013977:Tibia / Q000000981:diagnostic imaging; D014457:Ulna / Q000000981:diagnostic imaging