[Disorders of bone and mineral metabolism in CKD: CKD-MBD as a new entity].
Since vascular calcification due to mineral disorder has been revealed a chief cause of decreasing life expectancy of chronic kidney disease (CKD) patients in recent years, the term "renal osteodystrophy" can no longer express the pathophysiology of entire bone and mineral disorder in CKD. This is the reason why new disease entity "CKD-bone mineral disorden (MBD)" was introduced by the GBMI (Global Bone and Mineral Initiative) (one of the workgroups of KDIGO [Kidney Disease Improving Global Outcome]). GBMI has also produced new pathological classification of renal osteodystrophy (ROD) as TMV (turnover, mineralization, volume) classification and LBC (laboratory abnormalities, bone abnormalities, extra osseous calcification) classification for CKD-MBD.
Tsukamoto
Yusuke
Y
Shuwa General Hospital, Division of Nephrology, Japan.
D015519:Bone Density; D001847:Bone Diseases / Q000145:classification / Q000209:etiology*; D012080:Chronic Kidney Disease-Mineral and Bone Disorder / Q000378:metabolism; D006801:Humans; D007676:Kidney Failure, Chronic / Q000145:classification / Q000378:metabolism*