title: Treating delusional disorder: a comparison of cognitive-behavioural therapy and attention placebo control.
abstract: OBJECTIVE
  Cognitive-behavioural therapy (CBT) has proved effective in treating delusions, both in schizophrenia and delusional disorder (DD). Clinical trials of DD have mostly compared CBT with either treatment as usual, no treatment, or a wait-list control. This current study aimed to assess patients with DD who received CBT, compared with an attention placebo control (APC) group.
  
  
  METHODS
  Twenty-four individuals with DD were randomly allocated into either CBT or APC groups for a 24-week treatment period. Patients were diagnosed on the basis of structured clinical interviews for mental disorders and the Maudsley Assessment of Delusion Schedule (MADS).
  
  
  RESULTS
  Completers in both groups (n = 11 for CBT; n = 6 for APC) showed clinical improvement on the MADS dimensions of Strength of Conviction, Insight, Preoccupation, Systematization, Affect Relating to Belief, Belief Maintenance Factors, and Idiosyncrasy of Belief.
  
  
  CONCLUSIONS
  When compared with APC, CBT produced more impact on the MADS dimensions for Affect Relating to Belief, Strength of Conviction, and Positive Actions on Beliefs.
authors.affiliation: Fernand-Seguin Research Centre, Montreal, Quebec. kieron.oconnor@umontreal.ca
authors.forename: Kieron
authors.initials: K
authors.lastname: O'Connor
authors.forename: Emmanuel
authors.initials: E
authors.lastname: Stip
authors.forename: Marie-Claude
authors.initials: MC
authors.lastname: Pélissier
authors.forename: Frederick
authors.initials: F
authors.lastname: Aardema
authors.forename: Stéphane
authors.initials: S
authors.lastname: Guay
authors.forename: Gilles
authors.initials: G
authors.lastname: Gaudette
authors.forename: Ian
authors.initials: I
authors.lastname: Van Haaster
authors.forename: Sophie
authors.initials: S
authors.lastname: Robillard
authors.forename: Sébastien
authors.initials: S
authors.lastname: Grenier
authors.forename: Yves
authors.initials: Y
authors.lastname: Careau
authors.forename: Pascale
authors.initials: P
authors.lastname: Doucet
authors.forename: Vicky
authors.initials: V
authors.lastname: Leblanc
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D014150:Antipsychotic Agents / Q000627:therapeutic use*; D001288:Attention; D015928:Cognitive Behavioral Therapy / Q000379:methods*; D003702:Delusions / Q000175:diagnosis / Q000188:drug therapy / Q000628:therapy*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010868:Pimozide / Q000627:therapeutic use*; D018967:Risperidone / Q000627:therapeutic use*; D011795:Surveys and Questionnaires; D016896:Treatment Outcome
chemical_list: D014150:Antipsychotic Agents; D010868:Pimozide; D018967:Risperidone