Primary diffuse large B-cell lymphoma of the testis: a case-report.
We report a case of a primary non-Hodgkin lymphoma of the testis in a 74-year-old man presented with a 1-month history of testicular swelling. The patient was submitted to right inguinal orchidectomy for the definitive diagnosis. Light microscopy demonstrated sheets of lymphoma cells involving epididymis and rete testis, but mainly extended into testicular parenchyma. The malignant cells were large with scant cytoplasm and large vesicular nuclei, the classic appearance of a diffuse large B-cell lymphoma. The immunohistochemical study was carried out, with the tumour cells being intensively positive for CD45, CD20 and Ki67 nuclear proliferative antigen. Clinical and pathological features of this non-Hodgkin lymphoma are described and discussed.
Lamendola
Maria Gaetana
MG
Istituto di Anatomia Patologica, Seconda Università degli Studi, Napoli, Italy.
Ferraraccio
Franca
F
Pane
Umberto
U
De Luca
Giovanni
G
D'Armiento
Massimino
M
Autorino
Riccardo
R
D000368:Aged; D018951:Antigens, CD20 / Q000032:analysis; D014408:Biomarkers, Tumor / Q000032:analysis; D006801:Humans; D007150:Immunohistochemistry; D019394:Ki-67 Antigen / Q000032:analysis; D017493:Leukocyte Common Antigens / Q000032:analysis; D016403:Lymphoma, Large B-Cell, Diffuse / Q000737:chemistry / Q000276:immunology / Q000473:pathology / Q000601:surgery; D008297:Male; D009919:Orchiectomy; D013736:Testicular Neoplasms / Q000737:chemistry / Q000276:immunology / Q000473:pathology / Q000601:surgery; D016896:Treatment Outcome
D018951:Antigens, CD20; D014408:Biomarkers, Tumor; D019394:Ki-67 Antigen; D017493:Leukocyte Common Antigens; C516769:PTPRC protein, human