A primer on aldosterone for gynecologists/obstetricians.
An historical perspective on the role of aldosterone in the pathophysiology of hypertension and heart disease, and data supporting the advantages of blocking the mineralocorticoid receptor with anti-aldosterone agents.
Pitt
Bertram
B
Department of Internal Medicine, University of Michigan, Ann Arbor, USA. bpitt@umich.edu
D000450:Aldosterone / Q000502:physiology*; D005260:Female; D006176:Gynecology; D006333:Heart Failure / Q000503:physiopathology*; D006801:Humans; D006973:Hypertension / Q000503:physiopathology*; D000451:Mineralocorticoid Receptor Antagonists; D009774:Obstetrics; D017698:Postmenopause / Q000502:physiology; D018161:Receptors, Mineralocorticoid / Q000502:physiology; D012084:Renin-Angiotensin System / Q000502:physiology
D000451:Mineralocorticoid Receptor Antagonists; D018161:Receptors, Mineralocorticoid; D000450:Aldosterone