title: Imported and indigenous BSE cases in Germany.
abstract: Bovine spongiform encephalopathy (BSE) is a transmissible fatal neurodegenerative disease in cattle with an average incubation time of five years. The first BSE case in an indigenous cow was detected in Germany in November 2000. This was almost eight years after the huge BSE epidemic in the United Kingdom had peaked, and several years after many EU member states had seen their first BSE case. In the 1990s, BSE had been diagnosed in six imported animals in Germany. However, after the implementation of an active surveillance programme using BSE rapid testing systems, 399 indigenous German BSE cases have been found up to the end of July 2006. The birth cohorts of 1995-1997 contribute to the vast majority of the first 250 German cases that were diagnosed between 2000 and 2003. However, the most recent German BSE cases belong primarily to the birth cohorts 1998-2000 which is indicative of a recycling of BSE infectivity at that time. Moreover, there were two BSE cases in cattle born in spring 2001, i.e. after the meat and bone meal feed ban had come into effect on 2nd December 2000. In this article, we describe the dynamics of the German BSE epidemic and compare these data with those of other countries that observed larger numbers of cases.
authors.affiliation: Friedrich-Loeffler-Institut (FLI), Institute for Novel and Emerging Infectious Diseases, Boddenblick 5a, 17493 Greifswald, Insel Riems, Germany.
authors.forename: Anne
authors.initials: A
authors.lastname: Buschmann
authors.forename: Franz J
authors.initials: FJ
authors.lastname: Conraths
authors.forename: Thomas
authors.initials: T
authors.lastname: Selhorst
authors.forename: Julia
authors.initials: J
authors.lastname: Schultz
authors.forename: Matthias
authors.initials: M
authors.lastname: Kramer
authors.forename: Martin H
authors.initials: MH
authors.lastname: Groschup
mesh_terms: D000821:Animal Feed / Q000009:adverse effects; D000818:Animals; D002417:Cattle; D003132:Commerce; D004196:Disease Outbreaks / Q000662:veterinary*; D016643:Encephalopathy, Bovine Spongiform / Q000453:epidemiology* / Q000209:etiology; D005858:Germany / Q000453:epidemiology; D018571:Sentinel Surveillance / Q000662:veterinary