title: Fluorous synthesis of sclerotigenin-type benzodiazepine-quinazolinones.
abstract: A new synthetic protocol for sclerotigenin-type benzodiazepine-quinazolinone library scaffold is introduced. A fluorous benzyl protecting group is used for synthesis of 4-benzodiazepine-2,5-dione intermediate and also as a phase tag for fluorous solid-phase extraction (F-SPE).
authors.affiliation: Fluorous Technologies, Inc., University of Pittsburgh Applied Research Center, 970 William Pitt Way, Pittsburgh, PA 15238, USA.
authors.forename: Wei
authors.initials: W
authors.lastname: Zhang
authors.forename: John P
authors.initials: JP
authors.lastname: Williams
authors.forename: Yimin
authors.initials: Y
authors.lastname: Lu
authors.forename: Tadamichi
authors.initials: T
authors.lastname: Nagashima
authors.forename: Qainli
authors.initials: Q
authors.lastname: Chu