Dinuclear ruthenium(II) triple-stranded helicates: luminescent supramolecular cylinders that bind and coil DNA and exhibit activity against cancer cell lines.
Pascu
Gabriel I
GI
School of Chemistry, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK.
Hotze
Anna C G
AC
Sanchez-Cano
Carlos
C
Kariuki
Benson M
BM
Hannon
Michael J
MJ
D000970:Antineoplastic Agents / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D001665:Binding Sites; D045744:Cell Line, Tumor; D018360:Crystallography, X-Ray; D004247:DNA / Q000737:chemistry* / Q000187:drug effects; D004354:Drug Screening Assays, Antitumor; D006801:Humans; D008024:Ligands; D049449:Luminescence; D046911:Macromolecular Substances / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D008958:Models, Molecular; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D012428:Ruthenium / Q000737:chemistry*; D013329:Structure-Activity Relationship
D000970:Antineoplastic Agents; D008024:Ligands; D046911:Macromolecular Substances; D009942:Organometallic Compounds; D012428:Ruthenium; D004247:DNA