title: [Fluoride levels in saliva after tooth-brushing using fluoride toothpastes with and without rinsing of oral cavity].
abstract: OBJECTIVE
  The aim of the study was to determine salivary fluoride concentrations after tooth-brushing with fluoride toothpastes with and without rinsing of oral cavity.
  
  
  METHODS
  Fluoride levels in the supernatant of unstimulated mixed saliva were measured after tooth-brushing with Elmex (amine fluoride, 0.125% F) and Meridol (amine fluoride, stannous(II) fluoride, 0.14% F) toothpaste with and without rinsing. Fluoride concentration was measured using a fluoride ion-specific electrode (Orion 96 09BN) connected to a CPI-551 computer. The study was done in 120 subjects from whom salivary samples were taken before and after 15 and 30 min. from tooth-brushing with and without rinsing.
  
  
  RESULTS
  Fluoride levels in saliva correlated with time from tooth-brushing and with oral cavity rinsing. Toothbrushing with rinsing led to similar increase/decrease in fluoride level in saliva for both toothpastes. The use of toothpaste without rinsing vs rinsing produced a two-fold increase in the level of salivary fluoride in the case of Elmex and a three-fold increase in the case of Meridol toothpaste. Fluoride content in saliva 30 minutes after brushing was higher than baseline.
  
  
  CONCLUSIONS
  Significantly higher fluoride levels in saliva after tooth-brushing with fluoride toothpastes were noted when tooth-brushing was not followed by oral cavity rinsing.
authors.affiliation: Katedra i Zaklad Stomatologii Zachowawczej i Dzieciqcej Akademii Medycznej we Wrocławiu ul. Krakowska 26, 50-425 Wrocław.
authors.forename: Urszula
authors.initials: U
authors.lastname: Kaczmarek
authors.forename: Beata
authors.initials: B
authors.lastname: Pregiel
authors.forename: Alina
authors.initials: A
authors.lastname: Wrzyszcz-Kowalczyk
authors.forename: Iwona
authors.initials: I
authors.lastname: Grzesiak
authors.forename: Katarzyna
authors.initials: K
authors.lastname: Fita
mesh_terms: D000328:Adult; D000588:Amines / Q000008:administration & dosage* / Q000493:pharmacokinetics; D001682:Biological Availability; D003959:Diamines; D004338:Drug Combinations; D005260:Female; D005459:Fluorides / Q000008:administration & dosage / Q000032:analysis* / Q000493:pharmacokinetics; D005460:Fluorides, Topical / Q000008:administration & dosage / Q000493:pharmacokinetics; D006801:Humans; D017736:Ion-Selective Electrodes; D008297:Male; D009055:Mouth / Q000737:chemistry*; D009067:Mouthwashes; D012463:Saliva / Q000737:chemistry* / Q000378:metabolism; D014002:Tin Fluorides / Q000008:administration & dosage* / Q000493:pharmacokinetics; D014099:Toothbrushing
chemical_list: D000588:Amines; D003959:Diamines; D004338:Drug Combinations; D005460:Fluorides, Topical; D009067:Mouthwashes; D014002:Tin Fluorides; C059813:Meridol; C075174:amine fluoride gel; C495399:Olaflur; D005459:Fluorides