title: Acute isodense intracerebral haematoma due to coagulopathy associated with prostate cancer.
abstract: Prostate cancer can be complicated by spontaneous intracranial haematoma. In the acute setting, an intracranial haematoma can appear isodense on CT scanning, especially if a coagulopathy is present. Diffuse intravascular coagulation (DIC) can be the underlying pathophysiological mechanism that leads to spontaneous bleeding. It is important to recognize the possibility of DIC in cancer patients, since it has important therapeutical implications that may be life saving.
authors.affiliation: Department of Neurology, Canisius-Wilhelmina Hospital, Nijmegen, The Netherlands.
authors.forename: Franka
authors.initials: F
authors.lastname: Claes
authors.forename: Caroline V M
authors.initials: CV
authors.lastname: Verhagen
authors.forename: Wim I M
authors.initials: WI
authors.lastname: Verhagen
authors.forename: Ewout
authors.initials: E
authors.lastname: Schaafsma
authors.forename: Rob J
authors.initials: RJ
authors.lastname: Rongen
mesh_terms: D000368:Aged; D001859:Bone Neoplasms / Q000150:complications / Q000473:pathology / Q000556:secondary*; D001921:Brain / Q000473:pathology; D002543:Cerebral Hemorrhage / Q000209:etiology* / Q000473:pathology; D003937:Diagnosis, Differential; D004211:Disseminated Intravascular Coagulation / Q000150:complications* / Q000473:pathology; D004292:Dominance, Cerebral / Q000502:physiology; D005158:Facial Paralysis / Q000209:etiology / Q000473:pathology; D017809:Fatal Outcome; D006406:Hematoma / Q000209:etiology* / Q000473:pathology; D006429:Hemiplegia / Q000209:etiology / Q000473:pathology; D006801:Humans; D008297:Male; D009460:Neurologic Examination; D011471:Prostatic Neoplasms / Q000150:complications* / Q000473:pathology; D014057:Tomography, X-Ray Computed