title: Supercritical carbon dioxide: putting the fizz into biomaterials.
abstract: This paper describes recent progress made in the use of high pressure or supercritical fluids to process polymers into three-dimensional tissue engineering scaffolds. Three current examples are highlighted: foaming of acrylates for use in cartilage tissue engineering; plasticization and encapsulation of bioactive species into biodegradable polyesters for bone tissue engineering; and a novel laser sintering process used to fabricate three-dimensional biodegradable polyester structures from particles prepared via a supercritical route.
authors.affiliation: Tissue Engineering Group, School of Pharmacy, The University of Nottingham, University Park, Nottingham NG7 2RD, UK.
authors.forename: John J A
authors.initials: JJ
authors.lastname: Barry
authors.forename: Marta M C G
authors.initials: MM
authors.lastname: Silva
authors.forename: Vladimir K
authors.initials: VK
authors.lastname: Popov
authors.forename: Kevin M
authors.initials: KM
authors.lastname: Shakesheff
authors.forename: Steven M
authors.initials: SM
authors.lastname: Howdle
mesh_terms: D001672:Biocompatible Materials / Q000737:chemistry*; D002245:Carbon Dioxide / Q000737:chemistry*; D025924:Chromatography, Supercritical Fluid / Q000379:methods*; D008968:Molecular Conformation; D049329:Nanostructures / Q000737:chemistry* / Q000648:ultrastructure*; D011108:Polymers / Q000737:chemistry*; D011312:Pressure
chemical_list: D001672:Biocompatible Materials; D011108:Polymers; D002245:Carbon Dioxide