Diabetes mellitus is a multivariate independent prognostic factor in endometrial carcinoma: a clinicopathologic study on 313 patients.
OBJECTIVE
The aim of this study was to analyse the influence of diabetes mellitus as a prognostic factor for overall survival in endometrial cancer.


METHODS
Charts were reviewed from patients with endometrial carcinoma from 1985 to 2003. Data on clinicopathologic variables, adjuvant treatment, site of recurrence and survival were collected. The chi-square test was used to examine associations between variables. The Kaplan-Meier method was used for survival analysis and Cox's proportional hazards model for multiple regression analysis.


RESULTS
Multivariate analysis revealed that diabetes mellitus, FIGO stage and depth of myometrial invasion were significantly associated with overall survival.
Steiner
E
E
Department of Obsterics and Gynaecology , Johannes Gutenberg-University, Mainz, Germany.
Plata
K
K
Interthal
C
C
Schmidt
M
M
Faldum
A
A
Hengstler
J G
JG
Sakuragi
N
N
Watari
H
H
Yamamoto
R
R
Kölbl
H
H
D000328:Adult; D000368:Aged; D015897:Comorbidity; D003920:Diabetes Mellitus / Q000453:epidemiology*; D016889:Endometrial Neoplasms / Q000453:epidemiology* / Q000473:pathology*; D005260:Female; D005858:Germany / Q000453:epidemiology; D006801:Humans; D008875:Middle Aged; D015999:Multivariate Analysis; D009361:Neoplasm Invasiveness; D009367:Neoplasm Staging; D011379:Prognosis; D016016:Proportional Hazards Models; D012189:Retrospective Studies; D016019:Survival Analysis; D016387:Women's Health