Central airway obstruction caused by a peripheral hamartoma.
We report the first case of a hamartoma, arising from peripheral lung tissue, which extended proximally over several decades to occlude the large airways. The patient's symptoms were originally attributed to asthma and the correct diagnosis was only made when she developed life-threatening airway obstruction. The endobronchial component of the hamartoma was debulked with urgent laser therapy, while the peripheral base of the tumour was resected by elective right middle lobectomy.
Goodman
Anna
A
Wellcome Trust Centre for Human Genetics, Roosevelt Drive, Oxford OX3 7BN, United Kingdom. goodmana@well.ox.ac.uk
Falzon
Mary
M
Gelder
Colin
C
George
Jeremy
J
D000402:Airway Obstruction / Q000175:diagnosis* / Q000209:etiology; D005260:Female; D006222:Hamartoma / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D008175:Lung Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D008875:Middle Aged