title: Standardisation of parameters during endovenous laser therapy of truncal varicose veins--experimental ex-vivo study.
abstract: BACKGROUND
  Vein shrinkage is a surrogate marker for successful laser treatment of varicose veins. However, many controversies still remain concerning the best laser parameters to use. The aim of this study was standardisation of intraoperative energy dosages and pull-back rates to achieve optimal clinical results.
  
  
  METHODS
  Ex-vivo study in surgically removed saphenous trunks.
  
  
  METHODS
  Great saphenous veins were removed by Babcock stripping and irradiated with laser energy delivered by a laser diode emitting at 980 nm. In total, 279 vein segments (5 cm long) were treated using powers from 5-15 W. Vein segments were opened longitudinally and the circumference measured in the treated and untreated regions to assess thermal shrinkage.
  
  
  RESULTS
  The greatest shrinkage and minimum number of perforations was achieved using lower or medium power (8 to 12 W) with longer exposure to administer laser energy. The median percentage vein shrinkage was 50% (power 5 W), 45% (8 W), 40% (10 W), 45% (12 W) and 59% (15 W). When a higher power was used (15 W), the perforations were more frequent and carbonisation was marked.
  
  
  CONCLUSIONS
  Our data suggests that similar efficacy with fewer vein perforations may be obtained with low or medium power settings and increased exposure when undertaking laser obliteration of saphenous trunks. This may result in fewer adverse events such as ecchymosis following treatment in patients.
authors.affiliation: Institute of Medical Studies, University of Pardubice, Pardubice, Czech Republic. kaspar@flebocentrum.cz
authors.forename: S
authors.initials: S
authors.lastname: Kaspar
authors.forename: J
authors.initials: J
authors.lastname: Siller
authors.forename: Z
authors.initials: Z
authors.lastname: Cervinkova
authors.forename: T
authors.initials: T
authors.lastname: Danek
mesh_terms: D006801:Humans; D053685:Laser Therapy / Q000009:adverse effects / Q000379:methods / Q000592:standards*; D017410:Practice Guidelines as Topic; D012501:Saphenous Vein / Q000473:pathology / Q000601:surgery*; D014648:Varicose Veins / Q000473:pathology / Q000601:surgery*