Azelaic acid (15% gel) in the treatment of acne rosacea.
In December of 2002, the FDA approved azelaic acid 15% gel for the topical treatment of inflammatory papules and pustules of mild to moderate rosacea. Azelaic acid is a saturated dicarboxylic acid, which is naturally occurring and has been used in the treatment of rosacea, acne, and melasma. The 15% gel has a high efficacy and is generally well tolerated, with the local irritation (burning, stinging, itching, and scaling) being typically mild and transient. Azelaic acid 15% gel is considered effective and safe as a therapy for inflammatory papulo-pustular rosacea and is suitable for use on all skin types.
Gupta
Aditya K
AK
Division of Dermatology, Department of Medicine, Sunnybrook and Women's College Health Sciences Center, University of Toronto, Toronto, Ontario, Canada. gupta@execulink.com
Gover
Melissa D
MD
D003879:Dermatologic Agents / Q000009:adverse effects / Q000627:therapeutic use*; D003998:Dicarboxylic Acids / Q000009:adverse effects / Q000627:therapeutic use*; D005782:Gels; D006801:Humans; D009824:Ointments; D016032:Randomized Controlled Trials as Topic; D012393:Rosacea / Q000188:drug therapy*; D016896:Treatment Outcome
D003879:Dermatologic Agents; D003998:Dicarboxylic Acids; D005782:Gels; D009824:Ointments; C010038:azelaic acid