title: [Use of anti-thrombotic agents--monotherapy or combination and risk of upper gastrointestinal bleedings: a population-based case-control study. Secondary publication].
abstract: The clinical use of anti-thrombotic agents has shifted towards more aggressive therapy and towards regimes with more than one drug. Data on the risk of upper gastrointestinal bleedings (UGB) with combined anti-thrombotic therapy are scarce. In the period 2000 through 2004, 1,443 cases of serious UGB and 57,720 control subjects were identified in Funen County. Anti-thrombotic therapy is becoming increasingly aggressive. Combined anti-thrombotic therapy confers particular risk and is associated with high incidence rates of GI bleeding.
authors.affiliation: Syddansk Universitet, Afdelingen for Klinisk Farmakologi, IST, Forskningsenheden for almen medicin, Odense. jhallas@health.sdu.dk
authors.forename: Jesper
authors.initials: J
authors.lastname: Hallas
authors.forename: Michael
authors.initials: M
authors.lastname: Dall
authors.forename: Alin
authors.initials: A
authors.lastname: Andries
authors.forename: Birthe Søgaard
authors.initials: BS
authors.lastname: Andersen
authors.forename: Claus
authors.initials: C
authors.lastname: Aalykke
authors.forename: Jane Møller
authors.initials: JM
authors.lastname: Hansen
authors.forename: Morten
authors.initials: M
authors.lastname: Andersen
authors.forename: Annmarie Touborg
authors.initials: AT
authors.lastname: Lassen