title: Surgical outcomes of partial nephrectomy for renal cell carcinoma: a joint study by the Japanese Society of Renal Cancer.
abstract: OBJECTIVE
  A joint study was undertaken by the Japanese Society of Renal Cancer to investigate the present status of partial nephrectomy in Japan and to speculate about what may be the indications for partial nephrectomy in patients with renal cell carcinoma.
  
  
  METHODS
  Data were tabulated for 469 patients from participating medical institutions and various clinical factors were investigated with regard to disease progression (local recurrence and distant metastasis).
  
  
  RESULTS
  Disease progression was observed in 21 patients (4.5%). No significant relation to disease progression was observed for sex, laterality, tumor histology, grade and tumor size. Although patients with solitary tumors displayed excellent prognosis irrespective of tumor diameter, patients with multiple tumors displayed a high likelihood of disease progression. Patients older than 77 years old and patients with imperative indication were found to have a poorer prognosis.
  
  
  CONCLUSIONS
  In patients with solitary tumors, partial nephrectomy can be actively performed, even if the patient displays elective indications and the tumor is >4 cm in diameter. In patients displaying multiple tumors with imperative indications, the decision whether to perform partial nephrectomy should be made by the patients and their physicians after considering the impact on curability and the quality of life.
authors.affiliation: Department of Urology, Chigasaki Municipal Hospital, Kanagawa, Japan. uro@cg.netlaputa.ne.jp
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Senga
authors.forename: Seiichiro
authors.initials: S
authors.lastname: Ozono
authors.forename: Hayakazu
authors.initials: H
authors.lastname: Nakazawa
authors.forename: Satoshi
authors.initials: S
authors.lastname: Nagamori
authors.forename: Ken
authors.initials: K
authors.lastname: Marumo
authors.forename: Shigeo
authors.initials: S
authors.lastname: Horie
authors.forename: Tetsuro
authors.initials: T
authors.lastname: Onishi
authors.forename: Noriomi
authors.initials: N
authors.lastname: Miyao
authors.forename: Masahiro
authors.initials: M
authors.lastname: Nakao
authors.forename: Tatsuo
authors.initials: T
authors.lastname: Igarashi
authors.forename: Tomoyasu
authors.initials: T
authors.lastname: Tsushima
authors.forename: Michihiko
authors.initials: M
authors.lastname: Hasegawa
authors.forename: Masaru
authors.initials: M
authors.lastname: Murai
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002292:Carcinoma, Renal Cell / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D018572:Disease-Free Survival; D005260:Female; D005500:Follow-Up Studies; D019538:Health Care Surveys; D006801:Humans; D007564:Japan; D007680:Kidney Neoplasms / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D009392:Nephrectomy; D018579:Patient Selection; D016896:Treatment Outcome