O2 and N2O activation by Bi-, Tri-, and tetranuclear Cu clusters in biology.
Copper-cluster sites in biology exhibit unique spectroscopic features reflecting exchange coupling between oxidized Cu's and e (-) delocalization in mixed valent sites. These novel electronic structures play critical roles in O 2 binding and activation for electrophilic aromatic attack and H-atom abstraction, the 4e (-)/4H (+) reduction of O 2 to H 2O, and in the 2e (-)/2H (+) reduction of N 2O. These electronic structure/reactivity correlations are summarized below.
Solomon
Edward I
EI
Department of Chemistry, Stanford University, Stanford, California 94305, USA. Edward.Solomon@stanford.edu
Sarangi
Ritimukta
R
Woertink
Julia S
JS
Augustine
Anthony J
AJ
Yoon
Jungjoo
J
Ghosh
Somdatta
S
D001665:Binding Sites; D004156:Catechol Oxidase / Q000737:chemistry*; D003300:Copper / Q000737:chemistry*; D018360:Crystallography, X-Ray; D004578:Electron Spin Resonance Spectroscopy; D006433:Hemocyanins / Q000737:chemistry*; D008958:Models, Molecular; D014442:Monophenol Monooxygenase / Q000737:chemistry*; D009609:Nitrous Oxide / Q000737:chemistry*; D010084:Oxidation-Reduction; D010088:Oxidoreductases / Q000737:chemistry; D010100:Oxygen / Q000737:chemistry*; D013440:Sulfides / Q000737:chemistry
D013440:Sulfides; D003300:Copper; D006433:Hemocyanins; D010088:Oxidoreductases; D004156:Catechol Oxidase; D014442:Monophenol Monooxygenase; C022763:nitrous oxide reductase; D009609:Nitrous Oxide; D010100:Oxygen