title: Direct enantiomeric separations of tris(2-phenylpyridine) iridium (III) complexes on polysaccharide derivative-based chiral stationary phases.
abstract: A convenient method is presented for the first time for the direct separation of enantiomers of a tris(2-phenylpyridine) iridium (III) and an analog substituted with long alkoxy chains on polysaccharide derivative-based chiral stationary phases by HPLC. Tris(2-phenylpyridine) iridium (III) was separated on the immobilized amylose 3,5-dimethylphenylcarbamate (Chiralpak IA) using hexane/CHCl3/CH2Cl2 (75:20:5) as an eluent, and the analog could be separated on the coated cellulose 3,5-dimethyl-phenylcarbamate (Chiralcel OD) and cellulose 4-methylbenzoate (Chiralcel OJ) using hexane/2-propanol (96:4) as the eluent. CD spectra of the eluted HPLC fractions were also recorded, and the observed mirror image patterns confirm their enantioseparations.
authors.affiliation: EcoTopia Science Institute, Nagoya University, Furo-cho, Chikusa-ku, Nagoya, Japan.
authors.forename: Xiaoming
authors.initials: X
authors.lastname: Chen
authors.forename: Yoshio
authors.initials: Y
authors.lastname: Okamoto
authors.forename: Tomohiro
authors.initials: T
authors.lastname: Yano
authors.forename: Joe
authors.initials: J
authors.lastname: Otsuki
mesh_terms: D002851:Chromatography, High Pressure Liquid / Q000295:instrumentation* / Q000379:methods; D002942:Circular Dichroism; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry* / Q000302:isolation & purification*; D011134:Polysaccharides / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D009942:Organometallic Compounds; D011134:Polysaccharides; C520414:tris(2-phenylpyridine)iridium(III)