Preparation, molecular weight determination and structural studies of (polyvinylpyrrolidone)-oximate silico-benzoyl glycine copolymer with IR spectroscopy.
Polyvinylpyrrolidone (PVP)-oximate silico-benzoyl glycine (POSBG), a glycine copolymer, has been prepared with PVP-oxime and benzoyl glycine in 1 : 1 ratio, w/w, in ethanol medium.The ethanolic solution with silicic acid [Si(OH)4] as binder in same ratio was refluxed for 2-3 h resulting in a colloidal solution, which was further refluxed for 2 h and cooled to 37 degrees C for 15 min. After this a whitish solid material settled, which was separated by vacuum filtration followed by washing several times with aqueous ethanol at ordinary conditions. The average viscosity molecular weights Mv of PVP-oxime and the copolymer were determined with their respective dilute aqueous solutions. Primarily the calibration curves between the intrinsic viscosity (eta) data and their respective molecular weights of polyvinyl alcohol (PVOH) (marker)have been obtained to determine the Mv of oxime. Similarly the Mv of the copolymer was determined with the (eta) data of lysozyme (molecular weight=24,000 g mol(-1)), egg albumin(40,000 g mol (-1)) and BSA (65,000 g mol (-1)). The IR spectra of the PVP-oxime and copolymer were recorded in Nujol, which do not depict band frequency of -OH group of the binder. The 1602, 1688, 1182 and 1127 cm-1 stretching vibration frequencies noted in the spectra infer the presence of -C=N, -C=O, -Si-O-Si- and -Si-O-C- functional groups, respectively, in the copolymer.
Singh
Man
M
Chemistry Research Lab, Deshbandhu College, University of Delhi, New Delhi, India. mansingh50@hotmail.com
Chauhan
Sushila
S
D002850:Chromatography, Gel; D005998:Glycine / Q000737:chemistry*; D015394:Molecular Structure; D008970:Molecular Weight; D011108:Polymers / Q000138:chemical synthesis / Q000737:chemistry*; D011205:Povidone / Q000737:chemistry*; D013055:Spectrophotometry, Infrared / Q000379:methods*
D011108:Polymers; D011205:Povidone; D005998:Glycine