title: Intrarenal pure yolk sac tumor: an extremely rare entity.
abstract: Yolk sac tumor (endodermal sinus tumor) is a malignant germ cell tumor that usually arises in the gonads. Extragonadal germ cell tumors are rare and have been described in case reports. We report a pure intrarenal yolk sac tumor in a 1-year-old boy who presented with a huge abdominal mass and was operated for suspected Wilms tumor. The tumor exhibited histopathologic and immunohistochemical features identical to those of an endodermal sinus tumor of gonadal origin. The purpose of this report is to add a rare tumor to the differential diagnosis of pediatric renal neoplasms.
authors.affiliation: Department of Histopathology, Postgraduate Institute of Medical Education and Research, Chandigarh, India. yashwantk74@yahoo.com
authors.forename: Yashwant
authors.initials: Y
authors.lastname: Kumar
authors.forename: Alka
authors.initials: A
authors.lastname: Bhatia
authors.forename: Vijay
authors.initials: V
authors.lastname: Kumar
authors.forename: Kim
authors.initials: K
authors.lastname: Vaiphei
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D014408:Biomarkers, Tumor / Q000032:analysis; D001761:Bleomycin / Q000008:administration & dosage; D002945:Cisplatin / Q000008:administration & dosage; D003131:Combined Modality Therapy; D003937:Diagnosis, Differential; D018572:Disease-Free Survival; D018240:Endodermal Sinus Tumor / Q000737:chemistry / Q000473:pathology* / Q000628:therapy; D005047:Etoposide / Q000008:administration & dosage; D006801:Humans; D007223:Infant; D007680:Kidney Neoplasms / Q000737:chemistry / Q000473:pathology* / Q000628:therapy; D008297:Male; D010503:Periodic Acid-Schiff Reaction; D016896:Treatment Outcome; D009396:Wilms Tumor / Q000175:diagnosis
chemical_list: D014408:Biomarkers, Tumor; D001761:Bleomycin; D005047:Etoposide; D002945:Cisplatin