title: Normal percentage of CD56bright natural killer cells in young patients with a history of repeated unexplained implantation failure after in vitro fertilization cycles.
abstract: Changes in endometrial leukocyte subpopulations and most of all in the percentage of uterine natural-killer cells (uNK), during the menstrual cycles, may have a pivotal role in the implantation process. An increase of activated NK cells (CD56dim CD16+ CD69+) in the peripheral blood of patients with a reduced rate of embryo implantation in IVF treatment has been reported elsewhere, but we found, by using flow cytometry, normal endometrial lymphocyte subpopulations in young patients with a history of repeated unexplained implantation failure who were undergoing IVF cycles for idiopathic infertility.
authors.affiliation: Operative Unit of Obstetrics and Gynecology, Department of Surgical Sciences, University of Foggia, Foggia, Italy. m.matteo@unifg.it
authors.forename: Maria G
authors.initials: MG
authors.lastname: Matteo
authors.forename: Pantaleo
authors.initials: P
authors.lastname: Greco
authors.forename: Piergiorgio
authors.initials: P
authors.lastname: Rosenberg
authors.forename: Anna
authors.initials: A
authors.lastname: Mestice
authors.forename: Domenico
authors.initials: D
authors.lastname: Baldini
authors.forename: Teresa
authors.initials: T
authors.lastname: Falagario
authors.forename: Vincenzo
authors.initials: V
authors.lastname: Martino
authors.forename: Michele
authors.initials: M
authors.lastname: Santodirocco
authors.forename: Francesca
authors.initials: F
authors.lastname: Massenzio
authors.forename: Laura
authors.initials: L
authors.lastname: Castellana
authors.forename: Giorgina
authors.initials: G
authors.lastname: Specchia
authors.forename: Arcangelo
authors.initials: A
authors.lastname: Liso
mesh_terms: D000328:Adult; D019002:CD56 Antigen / Q000032:analysis*; D010064:Embryo Implantation; D004624:Embryo Transfer; D005260:Female; D005307:Fertilization in Vitro; D005434:Flow Cytometry; D006801:Humans; D007694:Killer Cells, Natural / Q000276:immunology*; D014599:Uterus / Q000166:cytology
chemical_list: D019002:CD56 Antigen