[Effect of probiotic lactic acid bacteria strains on virus infection].
The effect of probiotic lactic acid bacteria strains on viral infection was studied in experiments in vivo. It was shown that in investigations microbial substance based on living cells of L. plantarum and S. salivarius subsp. thermophilus strains manifested antiinfluenzal activity under administration of 0.3 ml of cultural medium per os at a dose of 3 x 10(8)/CFU mouse and antiherpetic activity at a dose of 0.3 x 10(9)/CFU mouse. The probiotic effectiveness was shown on the model of genital herpes of guinea-pigs at concentration of 1 x 10(9) cells/g.p. It was statistically established, that the lactic acid bacteria inhibited reproduction of HIV at a dose of cells of 0.1 x 10(9)/CFU ml.
Liaskovs'kyĭ
T M
TM
Rybalko
S L
SL
Pidhors'kyĭ
V S
VS
Kovalenko
N K
NK
Oleshchenko
L T
LT
D000818:Animals; D045744:Cell Line, Tumor; D002642:Chick Embryo; D003588:Cytopathogenic Effect, Viral; D004195:Disease Models, Animal; D005832:Genital Diseases, Male / Q000628:therapy / Q000821:virology; D006168:Guinea Pigs; D015497:HIV-1 / Q000187:drug effects; D006558:Herpes Genitalis / Q000628:therapy / Q000821:virology; D006561:Herpes Simplex / Q000628:therapy* / Q000821:virology; D018259:Herpesvirus 1, Human / Q000187:drug effects; D018258:Herpesvirus 2, Human / Q000187:drug effects; D006801:Humans; D053118:Influenza A Virus, H1N1 Subtype / Q000187:drug effects; D048191:Lactiplantibacillus plantarum / Q000145:classification / Q000254:growth & development*; D008297:Male; D051379:Mice; D009976:Orthomyxoviridae Infections / Q000628:therapy* / Q000821:virology; D019936:Probiotics / Q000008:administration & dosage / Q000627:therapeutic use*; D048249:Streptococcus thermophilus / Q000145:classification / Q000254:growth & development*