title: New dammarane triterpenes from Maytenus macrocarpa.
abstract: Two new dammarane triterpenes have been isolated from the stem bark exudates of Maytenus macrocarpa. Their structures were determined by extensive 1D and 2D NMR spectroscopic studies as 24(Z)-3-oxodammara-20(21),24-dien-27-oic acid (1) and octa-nor-13-hydroxydammara-1-en-3,17-dione (2). These compounds were tested for antitumoral activity.
authors.affiliation: Instituto Universitario de Bio-Orgánica Antonio González, Avda, Astrofísico Francisco Sánchez No2, La Laguna, 38206 Tenerife, Spain.
authors.forename: Virginia
authors.initials: V
authors.lastname: Torpocco
authors.forename: Haydee
authors.initials: H
authors.lastname: Chávez
authors.forename: Ana
authors.initials: A
authors.lastname: Estévez-Braun
authors.forename: Angel Gutiérrez
authors.initials: AG
authors.lastname: Ravelo
mesh_terms: D018744:DNA, Plant / Q000737:chemistry / Q000235:genetics; D009682:Magnetic Resonance Spectroscopy; D029755:Maytenus / Q000737:chemistry*; D012441:Saccharomyces cerevisiae / Q000378:metabolism; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet; D014315:Triterpenes / Q000737:chemistry* / Q000302:isolation & purification; D000097669:Dammaranes
chemical_list: D018744:DNA, Plant; D014315:Triterpenes; D000097669:Dammaranes; C520870:3-oxodammara-20(21),24-dien-27-oic acid; C520869:octa-nor-13-hydroxydammara-1-en-3,17-dione