title: Thalidomide therapy for the treatment of hypertrophic herpes simplex virus-related genitalis in HIV-infected individuals.
abstract: Hypertrophic genital herpes is a disfiguring manifestation of a common infection seen in immunocompromised hosts that can be clinically mistaken for malignancy. We review the literature and describe hypertrophic genital herpes in a human immunodeficiency virus-positive patient receiving antiretroviral therapy. Treatment with valacyclovir, cidofovir, and foscarnet failed, but thalidomide treatment was successful.
authors.affiliation: Department of Infectious Diseases, University of Texas Health Sciences Center at Houston, Houston, TX 77030, USA. andrea.m.e.holmes@uth.tmc.edu
authors.forename: Andrea
authors.initials: A
authors.lastname: Holmes
authors.forename: Mairín
authors.initials: M
authors.lastname: McMenamin
authors.forename: Fiona
authors.initials: F
authors.lastname: Mulcahy
authors.forename: Colm
authors.initials: C
authors.lastname: Bergin
mesh_terms: D000328:Adult; D005837:Genitalia, Male / Q000473:pathology; D015658:HIV Infections / Q000150:complications*; D006558:Herpes Genitalis / Q000150:complications / Q000188:drug therapy* / Q000473:pathology; D006801:Humans; D006984:Hypertrophy; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D008297:Male; D013792:Thalidomide / Q000627:therapeutic use*
chemical_list: D007166:Immunosuppressive Agents; D013792:Thalidomide