Thalidomide therapy for the treatment of hypertrophic herpes simplex virus-related genitalis in HIV-infected individuals.
Hypertrophic genital herpes is a disfiguring manifestation of a common infection seen in immunocompromised hosts that can be clinically mistaken for malignancy. We review the literature and describe hypertrophic genital herpes in a human immunodeficiency virus-positive patient receiving antiretroviral therapy. Treatment with valacyclovir, cidofovir, and foscarnet failed, but thalidomide treatment was successful.
Holmes
Andrea
A
Department of Infectious Diseases, University of Texas Health Sciences Center at Houston, Houston, TX 77030, USA. andrea.m.e.holmes@uth.tmc.edu
McMenamin
Mairín
M
Mulcahy
Fiona
F
Bergin
Colm
C
D000328:Adult; D005837:Genitalia, Male / Q000473:pathology; D015658:HIV Infections / Q000150:complications*; D006558:Herpes Genitalis / Q000150:complications / Q000188:drug therapy* / Q000473:pathology; D006801:Humans; D006984:Hypertrophy; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D008297:Male; D013792:Thalidomide / Q000627:therapeutic use*
D007166:Immunosuppressive Agents; D013792:Thalidomide