title: Expression of betaE and gamma-globin genes in infants heterozygous for hemoglobin E and double heterozygous for hemoglobin E and alpha-thalassemia.
abstract: This study described the expression of betaE-globin in newborns heterozygous for HbE. Despite the lower level of HbE, the pattern of betaE-globin gene expression was similar to betaA-globin because the increase in HbE and HbA reached the peak level at the same time. A delayed decline of HbF was observed.
authors.forename: Pranee
authors.initials: P
authors.lastname: Winichagoon
authors.forename: Saovaros
authors.initials: S
authors.lastname: Svasti
authors.forename: Pattanee
authors.initials: P
authors.lastname: Winichagoon
authors.forename: Chureeporn
authors.initials: C
authors.lastname: Chitchumroonchokchai
authors.forename: Suthat
authors.initials: S
authors.lastname: Fucharoen
mesh_terms: D000367:Age Factors; D002851:Chromatography, High Pressure Liquid; D005260:Female; D005312:Fetal Blood / Q000737:chemistry; D005319:Fetal Hemoglobin / Q000032:analysis; D005500:Follow-Up Studies; D005786:Gene Expression Regulation; D005914:Globins / Q000096:biosynthesis / Q000235:genetics*; D006441:Hemoglobin A / Q000032:analysis; D006446:Hemoglobin E / Q000032:analysis / Q000096:biosynthesis / Q000235:genetics*; D006455:Hemoglobins, Abnormal / Q000032:analysis / Q000235:genetics; D006456:Hemoglobinuria / Q000235:genetics*; D006579:Heterozygote; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D013785:Thailand / Q000453:epidemiology; D017085:alpha-Thalassemia / Q000235:genetics*
chemical_list: D006455:Hemoglobins, Abnormal; D005914:Globins; D006441:Hemoglobin A; D006446:Hemoglobin E; D005319:Fetal Hemoglobin; C030448:hemoglobin Bart's