title: Common carotid arterial thrombosis associated with ulcerative colitis.
abstract: A 26-year-old woman with ulcerative colitis was transferred to our hospital with left hemiparesis due to cerebral infarction. Cervical ultrasonography and magnetic resonance imaging angiography revealed thrombosis at the right common carotid artery and the right internal carotid artery. Antithrombotic and anticoagulant therapies were commenced. After about 2 wk of the treatment, the frequency of her diarrhea increased. She underwent emergency subtotal colectomy, but 10 d later an abundant hemorrhage from the remnant rectum occurred, so the remnant rectum was resected and an ileal pouch anal anastomosis was performed. Antithrombotic and anticoagulant therapies were continued, but neither her neurological status nor magnetic resonance imaging angiography findings showed subsequent changes. She was discharged 3 mon after operation. This is a rare case of common carotid arterial thrombosis occurring as a complication of ulcerative colitis, in which antithrombotic and anticoagulant therapies are considered to provoke a deterioration of the patient's bowel disease.
authors.affiliation: Division of Digestive and General Surgery, Department of Surgery, Niigata University, School of Medicine, Asahimachidouri1-757 Niigata, 951-8510, Japan. h-nogami@med.niigata-u.ac.jp
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Nogami
authors.forename: Tsuneo
authors.initials: T
authors.lastname: Iiai
authors.forename: Satoshi
authors.initials: S
authors.lastname: Maruyama
authors.forename: Tatsuo
authors.initials: T
authors.lastname: Tani
authors.forename: Katsuyoshi
authors.initials: K
authors.lastname: Hatakeyama
mesh_terms: D000328:Adult; D000925:Anticoagulants / Q000009:adverse effects / Q000627:therapeutic use; D002341:Carotid Artery Thrombosis / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology*; D017536:Carotid Artery, Common / Q000000981:diagnostic imaging / Q000473:pathology; D003093:Colitis, Ulcerative / Q000150:complications* / Q000601:surgery; D005260:Female; D006801:Humans; D018810:Magnetic Resonance Angiography; D016737:Proctocolectomy, Restorative; D014463:Ultrasonography
chemical_list: D000925:Anticoagulants