title: Cancer of the vulva in a 25-year-old woman with VIN III and high-grade cervical SIL--case report.
abstract: Human papillomavirus (HPV) infection is associated with an increase in intraepithelial lesions of the genital tract which are often multicentric. Following is a presentation of a case of vulvar cancer in a young woman (25 years of age) with multiple vulvar intraepithelial neoplasia (VIN III) lesions, a high-grade squamous intraepithelial cervical lesion, and a HPV type 16 infection at high risk of oncogenic transformation. This case offers an opportunity to discuss the risk factors that may favor the appearance of these lesions in young women, and their clinical management, diagnosis, and treatment.
authors.affiliation: Department of Obstetrics and Gynecolog, Hospital Sant Joan de Diu, University of Barcelona, Barcelona, Spain.
authors.forename: E
authors.initials: E
authors.lastname: González-Bosquet
authors.forename: M
authors.initials: M
authors.lastname: Sunol
authors.forename: A
authors.initials: A
authors.lastname: Hernandez
authors.forename: J
authors.initials: J
authors.lastname: Callejo
authors.forename: J M
authors.initials: JM
authors.lastname: Lailla
mesh_terms: D000328:Adult; D005260:Female; D052163:Human papillomavirus 6 / Q000302:isolation & purification*; D006801:Humans; D009361:Neoplasm Invasiveness; D009367:Neoplasm Staging; D030361:Papillomavirus Infections / Q000150:complications* / Q000175:diagnosis; D012307:Risk Factors; D014846:Vulvar Neoplasms / Q000473:pathology* / Q000821:virology*; D002578:Uterine Cervical Dysplasia / Q000821:virology*