Primary isolated extramedullary plasmacytoma of colon.
BACKGROUND
Extramedullary plasmacytoma is an uncommon entity that most commonly involves nasopharynx or upper respiratory tract. Involvement of the gastrointestinal tract occurs in approximated 10% of cases. Isolated primary plasmacytoma of colon is rare and only 7 well documented cases have been reported in the literature.


METHODS
We present a case of 42 year male who presented with diarrhea. Multiple colonic strictures were found on investigation. Colonoscopic biopsy was not helpful in making any specific diagnosis. Patient underwent subtotal colectomy. Isolated primary colonic plasmacytoma was found on histopathological examination.


CONCLUSIONS
Plasmacytoma is known to occur in extra osseous sites. Primary colonic plasmacytoma, however, is a rare clinical entity. Primary colonic plasmacytoma may have varying clinical presentations including multiple colonic strictures that may mimic colonic tuberculosis or inflammatory bowel disease. Although these cases are rare, treating physician as well as radiologist, and pathologist should be aware of this entity.
Gupta
Vishal
V
Department of Gastrointestinal Surgery, Gobind Ballabh Pant Hospital and Maulana Azad Medical College, New Delhi, India. drvg77@rediffmail.com
Nahak
Brindaban
B
Sakhuja
Puja
P
Agarwal
Anil K
AK
Kumar
Nirmal
N
Mishra
Pramod K
PK
D000328:Adult; D001707:Biopsy, Needle; D017024:Chemotherapy, Adjuvant; D003082:Colectomy / Q000379:methods; D003110:Colonic Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy*; D003113:Colonoscopy / Q000379:methods; D005500:Follow-Up Studies; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D010954:Plasmacytoma / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy*; D035583:Rare Diseases; D018570:Risk Assessment; D012812:Sigmoidoscopy / Q000379:methods; D016896:Treatment Outcome