Understanding the role of proteases and pH in wound healing.
Recent research into chronic and non-healing wounds has helped increase our knowledge and understanding of the destructive processes that occur in wounds. Advanced dressings, such as protease-modulating dressings, have been developed to reduce the effects of these processes and re-establish a molecular balance in the wound bed. To use these dressings accurately, nurses need to understand the events that occur at a molecular level in the wound bed and the phases of wound healing so that they can act appropriately if a wound becomes 'stuck' in one of these phases.
Rushton
I
I
Priory Fields Surgery, Huntingdon, Cambridgeshire.
D001458:Bandages; D002908:Chronic Disease; D019317:Evidence-Based Medicine; D006801:Humans; D006863:Hydrogen-Ion Concentration; D017053:Infection Control / Q000379:methods; D061965:Matrix Metalloproteinase Inhibitors; D020782:Matrix Metalloproteinases / Q000187:drug effects / Q000502:physiology*; D024802:Nurse's Role; D012307:Risk Factors; D017592:Skin Care / Q000379:methods* / Q000451:nursing; D014945:Wound Healing / Q000502:physiology*; D014946:Wound Infection / Q000150:complications / Q000517:prevention & control; D014947:Wounds and Injuries / Q000503:physiopathology / Q000517:prevention & control
D061965:Matrix Metalloproteinase Inhibitors; D020782:Matrix Metalloproteinases