Efficacy and tolerability of liposomal heparin spraygel as an add-on treatment in the management of superficial venous thrombosis.
Superficial venous thrombosis usually resolves spontaneously in a few weeks. In most cases, treatment includes peroral analgesics or nonsteroidal anti-inflammatory drugs accompanied by the recommendation to wear elastic stockings and perform regular mild ambulation. In contrast to this "standard treatment," a recent ACCP guideline has recommended that patients affected by spontaneous superficial thrombophlebitis be treated with intermediate doses of unfractionated or low-molecular-weight heparin. This study was designed to assess the efficacy of topically applied heparin spraygel in terms of reduction of local symptoms and signs of superficial venous thrombosis.
Katzenschlager
Reinhold
R
Department of Angiology, Hanuschkrankenhaus, Vienna, Austria. Reinhold.katzenschlager@wgkk.sozvers.at
Ugurlouglu
Ara
A
Sipos
Gyula
G
Bihari
Imre
I
Anyova
Eva B
EB
Hirschl
Mirko
M
Maruszynski
Marek
M
Noszczyk
Wojciech
W
Rybak
Zbigniew
Z
Cencora
Andrzej
A
D000287:Administration, Topical; D000328:Adult; D000925:Anticoagulants / Q000008:administration & dosage* / Q000009:adverse effects; D005260:Female; D005782:Gels; D006493:Heparin / Q000008:administration & dosage* / Q000009:adverse effects; D006801:Humans; D008081:Liposomes; D008297:Male; D008875:Middle Aged; D016896:Treatment Outcome; D020246:Venous Thrombosis / Q000188:drug therapy*
D000925:Anticoagulants; D005782:Gels; D008081:Liposomes; D006493:Heparin