title: Clostridium difficile-associated diarrhea after living donor liver transplantation.
abstract: OBJECTIVE
  To assess the incidence and analyze the risk factors for Clostridium difficile-associated diarrhea (CDAD) after living donor liver transplantation (LDLT) in adult.
  
  
  METHODS
  The microbiological data and medical records of 242 adult recipients that underwent LDLT at the Tokyo University Hospital were analyzed retrospectively. The independent risk factors for postoperative CDAD were identified.
  
  
  RESULTS
  Postoperative CDAD occurred in 11 (5%) patients. Median onset of CDAD was postoperative d 19 (range, 5-54). In the multivariate analyses, male gender (odds ratio, 4.56) and serum creatinine (>or= 1.5 mg/dL, odds ratio, 16.0) independently predicted postoperative CDAD.
  
  
  CONCLUSIONS
  CDAD should be considered in the differential diagnosis of patients with postoperative diarrhea after LDLT.
authors.affiliation: Artificial Organ and Transplantation Division, Department of Surgery, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan.
authors.forename: Masao
authors.initials: M
authors.lastname: Hashimoto
authors.forename: Yasuhiko
authors.initials: Y
authors.lastname: Sugawara
authors.forename: Sumihito
authors.initials: S
authors.lastname: Tamura
authors.forename: Junichi
authors.initials: J
authors.lastname: Kaneko
authors.forename: Yuichi
authors.initials: Y
authors.lastname: Matsui
authors.forename: Junichi
authors.initials: J
authors.lastname: Togashi
authors.forename: Masatoshi
authors.initials: M
authors.lastname: Makuuch
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D016360:Clostridioides difficile; D003404:Creatinine / Q000097:blood; D003967:Diarrhea / Q000382:microbiology*; D004761:Enterocolitis, Pseudomembranous / Q000150:complications* / Q000209:etiology; D005260:Female; D006801:Humans; D015994:Incidence; D016031:Liver Transplantation / Q000009:adverse effects*; D019520:Living Donors; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D051437:Renal Insufficiency / Q000097:blood / Q000150:complications; D012189:Retrospective Studies; D012307:Risk Factors; D012737:Sex Factors
chemical_list: D003404:Creatinine