title: The solution conformation of C-glycosyl analogues of the sialyl-Tn antigen.
abstract: The conformational behavior of two C-glycosyl analogues of the sialyl-Tn antigen has been determined by a combination of NMR methods and molecular mechanics calculations. Both compounds show a major solution conformation that is drastically different from the major one of the natural compound.
authors.affiliation: Centro de Investigaciones Biológicas, CSIC, Ramiro de Maeztu 9, 28040 Madrid, Spain.
authors.forename: Víctor
authors.initials: V
authors.lastname: García-Aparicio
authors.forename: Adeline
authors.initials: A
authors.lastname: Malapelle
authors.forename: Zouleika
authors.initials: Z
authors.lastname: Abdallah
authors.forename: Gilles
authors.initials: G
authors.lastname: Doisneau
authors.forename: José Ignacio
authors.initials: JI
authors.lastname: Santos
authors.forename: Juan Luis
authors.initials: JL
authors.lastname: Asensio
authors.forename: Francisco Javier
authors.initials: FJ
authors.lastname: Cañada
authors.forename: Jean Marie
authors.initials: JM
authors.lastname: Beau
authors.forename: Jesús
authors.initials: J
authors.lastname: Jiménez-Barbero
mesh_terms: D015295:Antigens, Tumor-Associated, Carbohydrate / Q000737:chemistry*; D002236:Carbohydrate Conformation; D004187:Disaccharides / Q000737:chemistry; D006031:Glycosylation; D009682:Magnetic Resonance Spectroscopy; D008958:Models, Molecular; D008968:Molecular Conformation; D019158:N-Acetylneuraminic Acid / Q000737:chemistry*; D012996:Solutions
chemical_list: D015295:Antigens, Tumor-Associated, Carbohydrate; D004187:Disaccharides; D012996:Solutions; C040286:Tn antigen; D019158:N-Acetylneuraminic Acid