title: Dysgerminoma of the ovary with precocious puberty: a case report.
abstract: Ovarian dysgerminoma is usually hormonally inert, but when it contains syncytiotrophoblastic giant cells or undergoes malignant transformation, the level of estradiol might be elevated. A 6-year-old girl contracted ovarian dysgerminoma with precocious puberty, and her levels of beta-human chorionic gondaotropin, alpha-fetoprotein and estradiol were high. After resection of the tumor, levels of tumor markers became normal and precocious puberty disappeared. We report this unusual type of dysgerminoma with a brief review of the literature.
authors.affiliation: Department of Obstetrics and Gynecology, Inha University School of Medicine, Incheon, South Korea.
authors.forename: Eun-Seop
authors.initials: ES
authors.lastname: Song
authors.forename: Jung-Pil
authors.initials: JP
authors.lastname: Lee
authors.forename: Jae-Ho
authors.initials: JH
authors.lastname: Han
authors.forename: Ho-Yeon
authors.initials: HY
authors.lastname: Kim
authors.forename: Se-Hee
authors.initials: SH
authors.lastname: Mun
authors.forename: Hee-Sug
authors.initials: HS
authors.lastname: Ryu
authors.forename: Ki-Hong
authors.initials: KH
authors.lastname: Chang
mesh_terms: D002648:Child; D003937:Diagnosis, Differential; D004407:Dysgerminoma / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D005260:Female; D006801:Humans; D007813:Laparotomy; D010051:Ovarian Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D011629:Puberty, Precocious; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography