title: Effective integration of systems biology, biomarkers, biosimulation, and modeling in streamlining drug development.
authors.affiliation: Merck Research Laboratories, Merck & Co, Inc, 126 East Lincoln Avenue, Rahway, NJ 07065, USA. rajesh_krishna@merck.com
authors.forename: Rajesh
authors.initials: R
authors.lastname: Krishna
authors.forename: Hans Guenter
authors.initials: HG
authors.lastname: Schaefer
authors.forename: Ole J
authors.initials: OJ
authors.lastname: Bjerrum
mesh_terms: D015415:Biomarkers; D035843:Biomedical Research / Q000458:organization & administration*; D003198:Computer Simulation; D004341:Drug Evaluation; D004353:Drug Evaluation, Preclinical; D004345:Drug Industry / Q000458:organization & administration*; D006801:Humans; D033183:Interdisciplinary Communication; D007880:Legislation, Drug; D008954:Models, Biological; D049490:Systems Biology
chemical_list: D015415:Biomarkers