Acute pancreatitis associated with ifosfamide.
Acute pancreatitis is a rare complication during chemotherapy for pediatric patients with solid tumors. We report a 9-year-old boy with osteosarcoma who experienced 2 episodes of pancreatitis 1 day and 48 days after infusion of ifosfamide (IFOS), respectively. From a MEDLINE search, this is the 3rd reported case and 2nd reported pediatric case of IFOS-induced pancreatitis, and only this case experienced late-onset pancreatitis.
Hung
Miao-Chiu
MC
Department of Pediatrics, Taipei Veterans General Hospital, and National Yang-Ming University School of Medicine, Taipei, Taiwan, R.O.C.
Hung
Giun-Yi
GY
Lin
Pei-Chin
PC
Tiu
Chui-Mei
CM
Tien
Yi-Ching
YC
D000208:Acute Disease; D018906:Antineoplastic Agents, Alkylating / Q000009:adverse effects*; D001859:Bone Neoplasms / Q000188:drug therapy; D002648:Child; D006801:Humans; D007069:Ifosfamide / Q000009:adverse effects*; D008297:Male; D012516:Osteosarcoma / Q000188:drug therapy; D010195:Pancreatitis / Q000139:chemically induced*
D018906:Antineoplastic Agents, Alkylating; D007069:Ifosfamide