[Oral ferric ammonium citrate solution in MRCP for diagnosing low-level obstructive jaundice].
OBJECTIVE
To evaluate the value of oral ferric ammonium citrate solution as a gastrointestinal contrast agent in diagnosing low-level obstructive jaundice.


METHODS
Thirty-six patients who were suspected of low-level obstructive jaundice were performed with magnetic resonance cholangiopancreatography (MRCP) and conventional MRI before and after the administration of oral ferric ammonium citrate solution. The diagnostic accuracy for evaluating the site and the cause of obstruction was compared with other diagnostic modalities.


RESULTS
The image qualities of single-slice and multi-slice MRCP were improved markedly. The accuracy of MRCP for evaluating the site of obstruction was 97.22%, which was superior to US (P<0.05). There were no significant differences among the MRCP, CT, and ERCP.


CONCLUSIONS
Oral ferric ammonium citrate solution can significantly improve the image quality of MRCP. FAC-MRCP is a simple, safe, and noninvasive technique with excellent accuracy in the diagnosis of low-level obstructive jaundice.
Yang
Pu
P
Hepatobiliary & Enteric Surgery Research Center, Central South University, Changsha, China.
Zhang
Yang-de
YD
Li
Nian-Feng
NF
Li
Wen-Zheng
WZ
Zhou
Gao-Feng
GF
D000284:Administration, Oral; D000328:Adult; D000368:Aged; D049448:Cholangiopancreatography, Magnetic Resonance / Q000379:methods*; D042883:Choledocholithiasis / Q000175:diagnosis; D003287:Contrast Media; D005260:Female; D005290:Ferric Compounds / Q000008:administration & dosage; D006801:Humans; D041781:Jaundice, Obstructive / Q000175:diagnosis*; D008297:Male; D008875:Middle Aged; D000644:Quaternary Ammonium Compounds / Q000008:administration & dosage; D012680:Sensitivity and Specificity
D003287:Contrast Media; D005290:Ferric Compounds; D000644:Quaternary Ammonium Compounds; C013531:ferric ammonium citrate