title: Accuracy of leukocyte alkaline phosphatase score to predict JAK2 V617F mutation.
abstract: Granulocyte activation parameters have been described in patients with myeloproliferative disorders (MPD). We have evaluated the accuracy of leukocyte alkaline phosphatase (LAP) score to predict JAK2 V617F mutation. LAP score was obtained using a cytochemical reaction in granulocytes of patients' peripheral blood with MPD.
authors.forename: Ana L
authors.initials: AL
authors.lastname: Basquiera
authors.forename: Fernanda
authors.initials: F
authors.lastname: Fassetta
authors.forename: Néstor
authors.initials: N
authors.lastname: Soria
authors.forename: José Moreno
authors.initials: JM
authors.lastname: Barral
authors.forename: Brenda
authors.initials: B
authors.lastname: Ricchi
authors.forename: Juan J
authors.initials: JJ
authors.lastname: García
mesh_terms: D000328:Adult; D000368:Aged; D000469:Alkaline Phosphatase / Q000097:blood*; D019943:Amino Acid Substitution; D019540:Area Under Curve; D005260:Female; D006801:Humans; D053614:Janus Kinase 2 / Q000235:genetics*; D007962:Leukocytes / Q000201:enzymology*; D008297:Male; D008875:Middle Aged; D020125:Mutation, Missense; D009196:Myeloproliferative Disorders / Q000097:blood* / Q000201:enzymology; D018375:Neutrophil Activation; D017354:Point Mutation; D011237:Predictive Value of Tests; D016037:Single-Blind Method
chemical_list: C507924:JAK2 protein, human; D053614:Janus Kinase 2; D000469:Alkaline Phosphatase