title: [Usefulness of interleukin 18 determination in clinical diagnostics].
abstract: Interleukin-18 (IL-18) is a proinflammatory pleiotropic cytokine playing a major role in the inflammatory cascade. It was written up for the first time in 1995 as a factor inducing interferon gamma in Kupffer cells, macrophages as well as T and B cells. Authors are presenting actual publications concerning usefulness in interleukin 18 determination in clinical diagnostics.
authors.affiliation: Zakład Diagnostyki, Katedra Biochemii Klinicznej, Collegium Medicum Uniwersytet Jagielloński w Krakowie. mbkusnie@cyf-kr.edu.pl
authors.forename: Beata
authors.initials: B
authors.lastname: Kuśnierz-Cabala
authors.forename: Danuta
authors.initials: D
authors.lastname: Galicka-Latała
authors.forename: Jerzy W
authors.initials: JW
authors.lastname: Naskalski
authors.forename: Jacek
authors.initials: J
authors.lastname: Sieradzki
mesh_terms: D050197:Atherosclerosis / Q000175:diagnosis / Q000378:metabolism; D015415:Biomarkers / Q000097:blood; D003920:Diabetes Mellitus / Q000175:diagnosis / Q000378:metabolism; D006801:Humans; D007249:Inflammation / Q000175:diagnosis / Q000378:metabolism; D007371:Interferon-gamma / Q000378:metabolism; D020382:Interleukin-18 / Q000032:analysis* / Q000037:antagonists & inhibitors / Q000378:metabolism*; D008107:Liver Diseases / Q000175:diagnosis / Q000378:metabolism; D009103:Multiple Sclerosis / Q000175:diagnosis / Q000378:metabolism; D009369:Neoplasms / Q000175:diagnosis / Q000378:metabolism; D016377:Organ Transplantation; D010195:Pancreatitis / Q000175:diagnosis / Q000378:metabolism; D011565:Psoriasis / Q000175:diagnosis / Q000378:metabolism; D053724:Receptors, Interleukin-18 / Q000032:analysis / Q000378:metabolism*
chemical_list: D015415:Biomarkers; D020382:Interleukin-18; D053724:Receptors, Interleukin-18; D007371:Interferon-gamma