title: Utilization of human cadaveric acellular dermis for abdominal hernia reconstruction.
abstract: BACKGROUND
  Incisional hernias with history of recurrence or infection remain a challenge, with high postoperative morbidity and recurrence rates. The purpose of this study is to evaluate outcomes of patients treated with human cadaveric acellular dermis as an adjunct to abdominal wall reconstruction.
  
  
  METHODS
  We retrospectively reviewed 39 abdominal wall reconstructions with human cadaveric acellular dermis performed in 37 patients and compared them with 39 randomly selected cases.
  
  
  RESULTS
  There is a significant decrease in recurrence rates when human cadaveric acellular dermis is added as an overlay to primary closure plus rectus muscle advancement and imbrication in patients with medium-sized hernias. No differences were observed when adding human cadaveric acellular dermis as an overlay to patients with large-size hernias treated with underlay mesh. The use of human cadaveric acellular dermis did not increase postoperative morbidity rates.
  
  
  CONCLUSIONS
  Improved results with human cadaveric acellular dermis are obtained by achieving tension-free repairs.
authors.affiliation: Division of Plastic Surgery, University of Alabama at Birmingham, Birmingham, AL, USA.
authors.forename: Antonio
authors.initials: A
authors.lastname: Espinosa-de-los-Monteros
authors.forename: Jorge I
authors.initials: JI
authors.lastname: de la Torre
authors.forename: Ian
authors.initials: I
authors.lastname: Marrero
authors.forename: Patricio
authors.initials: P
authors.lastname: Andrades
authors.forename: Michael R
authors.initials: MR
authors.lastname: Davis
authors.forename: Luis O
authors.initials: LO
authors.lastname: Vásconez
mesh_terms: D034861:Abdominal Wall / Q000601:surgery; D000293:Adolescent; D000328:Adult; D000368:Aged; D002102:Cadaver; D003094:Collagen; D020405:Dermis / Q000637:transplantation*; D005260:Female; D046449:Hernia, Abdominal / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies
chemical_list: C440568:Alloderm; D003094:Collagen