title: Relation of optical coherence tomography and unusual angiographic leakage patterns in central serous chorioretinopathy.
abstract: OBJECTIVE
  To investigate the anatomic basis of atypical angiographic leaks in central serous chorioretinopathy (CSC) with optical coherence tomography (OCT).
  
  
  METHODS
  Fluorescein angiography (FA) and OCT were performed in three eyes of three patients (two men, one woman) with CSC. The angiographic leaks were treated with transpupillary thermotherapy (TTT) in two patients with long-standing CSC. The investigations were repeated in the treated patients during follow-up visits.
  
  
  RESULTS
  Clinically, all patients demonstrated typical CSC; the female patient had subretinal fibrin under the detachment. FA showed unusual leakage patterns and OCT revealed bridging tissue connecting the pigment epithelial detachment (PED) to the overlying detached retina in all patients. CSC resolved completely in the two patients who underwent TTT along with normalization of the OCT findings. In one patient re-evaluated before complete resolution of CSC, OCT showed a flattened PED with disappearance of the bridging tissue and persistent serous detachment. FA demonstrated conversion of the previously atypical leak into a classic 'smokestack' configuration. Over the next month, leakage resolved completely. CSC and the anatomical findings persisted in the untreated patient.
  
  
  CONCLUSIONS
  OCT identified a potential anatomic basis for unusual angiographic leakage pattern in all three cases of CSC evaluated.
authors.affiliation: Retina-Vitreous Service, Aravind Eye Hospital and Postgraduate Institute of Ophthalmology, Madurai, Tamil Nadu, India. daksh@aravind.org
authors.forename: D
authors.initials: D
authors.lastname: Shukla
authors.forename: L P
authors.initials: LP
authors.lastname: Aiello
authors.forename: C
authors.initials: C
authors.lastname: Kolluru
authors.forename: S
authors.initials: S
authors.lastname: Baddela
authors.forename: R D
authors.initials: RD
authors.lastname: Jager
authors.forename: R
authors.initials: R
authors.lastname: Kim
mesh_terms: D000328:Adult; D015862:Choroid Diseases / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D005119:Extravasation of Diagnostic and Therapeutic Materials / Q000473:pathology; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D008297:Male; D012164:Retinal Diseases / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D041623:Tomography, Optical Coherence