title: The impact of recurrent abdominal pain: predictors of outcome in a large population cohort.
abstract: OBJECTIVE
  Recurrent abdominal pain is one of the commonest complaints of childhood, affecting approximately 10% of children at any one time. This study aims to describe the outcome of recurrent abdominal pain amongst 6-year-old children, and to identify risk factors (in both the children and their parents), which predict these outcomes.
  
  
  METHODS
  7128 6-year-old children in the Avon Longitudinal Study of Parents and Children (ALSPAC) were followed up for 1 year. The principle outcomes were abdominal pain, number of days missed from school in the preceding year and psychiatric diagnoses.
  
  
  RESULTS
  Children with recurrent abdominal pain at age 6 years had higher rates of further abdominal pain [odds ratio 4.88 (95% CI: 4.01, 5.95)], school absence (10 or more days off school in a year) [OR 1.89 (1.53, 2.33)] and anxiety disorders [OR 2.36 (1.68, 3.32)] at age 7 years. Maternal anxiety was the most consistent predictor of subsequent adverse outcomes for these children.
  
  
  CONCLUSIONS
  Children with recurrent abdominal pain are at significant and continuing risk of adverse functioning. It is important for clinicians to take a whole family perspective, and particularly to consider parental anxiety, when a child with recurrent abdominal pain presents to them.
authors.affiliation: Department of Psychiatry, Oxford University, Oxford, UK. paul.ramchandani@psych.ox.ac.uk
authors.forename: Paul G
authors.initials: PG
authors.lastname: Ramchandani
authors.forename: Mina
authors.initials: M
authors.lastname: Fazel
authors.forename: Alan
authors.initials: A
authors.lastname: Stein
authors.forename: Nicola
authors.initials: N
authors.lastname: Wiles
authors.forename: Matthew
authors.initials: M
authors.lastname: Hotopf
mesh_terms: D015746:Abdominal Pain / Q000523:psychology; D001007:Anxiety / Q000209:etiology; D002648:Child; D005192:Family Health; D005260:Female; D006801:Humans; D016015:Logistic Models; D008297:Male; D009035:Mothers / Q000523:psychology; D011379:Prognosis; D012008:Recurrence; D012307:Risk Factors