title: An agent approach for protein function analysis in a grid infrastructure.
abstract: Many tasks in bioinformatics can be faced only using a combination of computational tools. In particular, functional annotation of gene products can be a very expensive task that may require the application of many analysis together with a manual intervention of biologists. In this area, the phylogenomics inference is one of the most accurate analysis methodologies for functional annotation that is not yet widely used due to the computational cost of some steps in its protocol. This paper discusses the implementation and deployment of such analysis protocol in a distributed grid environment using an agent architecture in order to simplify the interaction between users and the grid.
authors.affiliation: Institute for Biomedical Technologies - Italian National Research Council, Via Fratelli Cervi 93, I-20090 Segrate (MI) - Italy. alessandro.orro@itb.cnr.it
authors.forename: Alessandro
authors.initials: A
authors.lastname: Orro
authors.forename: Luciano
authors.initials: L
authors.lastname: Milanesi
mesh_terms: D019295:Computational Biology; D006801:Humans; D007558:Italy; D008490:Medical Informatics / Q000458:organization & administration*; D010802:Phylogeny; D011506:Proteins / Q000032:analysis* / Q000235:genetics / Q000378:metabolism
chemical_list: D011506:Proteins