title: First Spanish case of onychomycosis caused by Chaetomium globosum.
abstract: Members of the fungal genus Chaetomium usually colonize cellulose-containing plant remains but on rare occasions may cause opportunistic mycoses and cutaneous infection in otherwise healthy individuals. To our knowledge, there have been only five credible descriptions of onychomycosis caused by members of this genus and only two of these contained information on therapy. We describe the first case of Chaetomium globosum onychomycosis recorded in Spain. The etiologic significance of the fungus was confirmed by its repeated isolation at different times, to the exclusion of dermatophytes. Clinically, the affected nails showed an excellent response to terbinafine and complete cure appeared to have been attained.
authors.affiliation: Microbiología, Hospital Royo Villanova, Zaragoza, Spain. caspiroz@ya.com
authors.forename: Carmen
authors.initials: C
authors.lastname: Aspiroz
authors.forename: Josepa
authors.initials: J
authors.lastname: Gené
authors.forename: Antonio
authors.initials: A
authors.lastname: Rezusta
authors.forename: Luis
authors.initials: L
authors.lastname: Charlez
authors.forename: Richard C
authors.initials: RC
authors.lastname: Summerbell
mesh_terms: D000328:Adult; D000935:Antifungal Agents / Q000627:therapeutic use; D002597:Chaetomium / Q000166:cytology / Q000302:isolation & purification*; D005533:Foot Dermatoses / Q000188:drug therapy / Q000382:microbiology* / Q000473:pathology; D006801:Humans; D008297:Male; D009281:Naphthalenes / Q000627:therapeutic use; D014009:Onychomycosis / Q000188:drug therapy / Q000382:microbiology* / Q000473:pathology; D013030:Spain; D000077291:Terbinafine
chemical_list: D000935:Antifungal Agents; D009281:Naphthalenes; D000077291:Terbinafine