title: [Contribution of nasal methicillin-resistant Staphylococcus aureus colonization to percutaneous endoscopic gastrostomy site infection and risk factors of wound infection].
abstract: OBJECTIVE
  Peristomal infection is the most common complication of percutaneous endoscopic gastrostomy (PEG) insertion. Methicillin-resistant Staphylococcus aureus (MRSA) is the most commonly implicated organism of peristomal infection. The aims of this study were to determine the contribution of nasal MRSA to wound infection in PEG and the predictors of wound infection.
  
  
  METHODS
  A prospective study was conducted on patients undergoing PEG between September 2003 and July 2005. All patients received antibiotics prior to PEG insertion. Nasal swabs were taken from a consecutive series of patients prior to PEG insertion. Wound status of the peristomal site were prospectively evaluated at day 1, 3, and 7 following the insertion of PEG.
  
  
  RESULTS
  Thirty-one patients underwent PEG insertion (mean age, 66+/-16 years). Ten patients (32.3%) had MRSA-positive nasal swabs. Peristomal infection did not have any relationship with nasal MRSA colonization (p>0.05). Peristomal infection occurred in 4 (12.9%) cases. The rate of peristomal infections was significantly higher in patients with diabetes mellitus (p<0.05).
  
  
  CONCLUSIONS
  Nasal MRSA colonization is not associated with the risk of peristomal infections in patients receiving antibiotics prior to PEG insertion. Diabetes mellitus might be the risk factor for peristomal infection after PEG insertion.
authors.affiliation: Department of Internal Medicine, Ewha Medical Research Institute, Ewha Womans University College of Medicine, Seoul, Korea.
authors.forename: Hee Jung
authors.initials: HJ
authors.lastname: Oh
authors.forename: Ki-Nam
authors.initials: KN
authors.lastname: Shim
authors.forename: Hee Jung
authors.initials: HJ
authors.lastname: Choi
authors.forename: Jong-Soo
authors.initials: JS
authors.lastname: Lee
authors.forename: Hyun Joo
authors.initials: HJ
authors.lastname: Song
authors.forename: Kum Hei
authors.initials: KH
authors.lastname: Ryu
authors.forename: Tae Hun
authors.initials: TH
authors.lastname: Kim
authors.forename: Sung-Ae
authors.initials: SA
authors.lastname: Jung
authors.forename: Kwon
authors.initials: K
authors.lastname: Yoo
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D048909:Diabetes Complications / Q000453:epidemiology; D005260:Female; D005773:Gastroscopy; D005774:Gastrostomy; D006801:Humans; D008297:Male; D008712:Methicillin / Q000494:pharmacology; D016106:Methicillin Resistance; D008875:Middle Aged; D009666:Nose / Q000382:microbiology; D012307:Risk Factors; D013203:Staphylococcal Infections / Q000453:epidemiology / Q000209:etiology / Q000382:microbiology*; D013211:Staphylococcus aureus / Q000187:drug effects / Q000302:isolation & purification*; D013530:Surgical Wound Infection / Q000453:epidemiology / Q000209:etiology / Q000382:microbiology*
chemical_list: D000900:Anti-Bacterial Agents; D008712:Methicillin