title: The anabolic and catabolic responses in bone repair.
abstract: The literature on fracture repair has been reviewed. The traditional concepts of delayed and nonunion have been examined in terms of the phased and balanced anabolic and catabolic responses in bone repair. The role of medical manipulation of these inter-related responses in the fracture healing have been considered.
authors.affiliation: The Children's Hospital at Westmead, Locked Bag 4001, Westmead, New South Wales 2145, Australia. DavidL3@chw.edu.au
authors.forename: D G
authors.initials: DG
authors.lastname: Little
authors.forename: M
authors.initials: M
authors.lastname: Ramachandran
authors.forename: A
authors.initials: A
authors.lastname: Schindeler
mesh_terms: D045930:Anabolic Agents / Q000627:therapeutic use; D019485:Bone Morphogenetic Proteins / Q000627:therapeutic use; D017102:Fracture Healing / Q000502:physiology*; D050723:Fractures, Bone / Q000378:metabolism*; D005599:Fractures, Ununited / Q000188:drug therapy / Q000378:metabolism / Q000503:physiopathology; D006801:Humans; D008954:Models, Biological
chemical_list: D045930:Anabolic Agents; D019485:Bone Morphogenetic Proteins