title: Prolapse severity, symptoms and impact on quality of life among women planning sacrocolpopexy.
abstract: OBJECTIVE
  To explore the relationship between severity of pelvic organ prolapse (POP), symptoms of pelvic dysfunction and quality of life using validated measures.
  
  
  METHODS
  Baseline data from 314 participants in the Colpopexy And Urinary Reduction Efforts (CARE) trial were analyzed. Pelvic symptoms and impact were assessed using the Pelvic Floor Distress Inventory (PFDI) and the Pelvic Floor Impact Questionnaire (PFIQ). PFDI and PFIQ scores were compared by prolapse stage and history of incontinence or POP surgery. Regression analyses were performed to identify other predictors of symptoms and impact.
  
  
  RESULTS
  Women were predominantly (90%) Caucasian and had mean age of 61 years. Women with stage II POP, especially those with prior surgery, reported more symptoms and impact than women with more advanced POP. There were no other significant predictors of symptoms or life impact.
  
  
  CONCLUSIONS
  Women planning sacrocolpopexy with stage II prolapse and prior pelvic surgery reported more symptoms and quality of life impact than those with more advanced prolapse.
authors.affiliation: Loyola University Medical Center, Maywood, IL, USA. Mfitzg8@lumc.edu
authors.forename: M P
authors.initials: MP
authors.lastname: Fitzgerald
authors.forename: N K
authors.initials: NK
authors.lastname: Janz
authors.forename: P A
authors.initials: PA
authors.lastname: Wren
authors.forename: J T
authors.initials: JT
authors.lastname: Wei
authors.forename: A M
authors.initials: AM
authors.lastname: Weber
authors.forename: C
authors.initials: C
authors.lastname: Ghetti
authors.forename: G W
authors.initials: GW
authors.lastname: Cundiff
mesh_terms: D000368:Aged; D005260:Female; D013509:Gynecologic Surgical Procedures; D006801:Humans; D008875:Middle Aged; D017773:Pelvic Floor; D011594:Psychometrics; D011788:Quality of Life; D012044:Regression Analysis; D012720:Severity of Illness Index; D014596:Uterine Prolapse / Q000503:physiopathology* / Q000523:psychology / Q000601:surgery