title: AgOTf-catalyzed three-component reactions of 2-alkynylbenzaldehydes, amines, and diethylphosphite. An efficient route to 2,3-disubstituted-1,2-dihydroisoquinolin-1-ylphosphonates.
abstract: AgOTf was discovered as a highly efficient catalyst in reactions of 2-alkynylbenzaldehydes, amines, and diethylphosphite, which provided a facile and efficient pathway for the synthesis of 2,3-disubstituted-1,2-dihydroisoquinolin-1-ylphosphonates.
authors.affiliation: Department of Chemistry, Fudan University, 220 Handan Road, Shanghai, 200433, P. R. China.
authors.forename: Wei
authors.initials: W
authors.lastname: Sun
authors.forename: Qiuping
authors.initials: Q
authors.lastname: Ding
authors.forename: Xiaoyu
authors.initials: X
authors.lastname: Sun
authors.forename: Renhua
authors.initials: R
authors.lastname: Fan
authors.forename: Jie
authors.initials: J
authors.lastname: Wu
mesh_terms: D000478:Alkylation; D000588:Amines / Q000737:chemistry*; D001547:Benzaldehydes / Q000737:chemistry*; D002384:Catalysis; D006859:Hydrogen / Q000737:chemistry*; D007546:Isoquinolines / Q000737:chemistry*; D008698:Mesylates / Q000737:chemistry*; D015394:Molecular Structure; D063065:Organophosphonates / Q000138:chemical synthesis / Q000737:chemistry*; D017905:Phosphites / Q000737:chemistry*
chemical_list: D000588:Amines; D001547:Benzaldehydes; D007546:Isoquinolines; D008698:Mesylates; D063065:Organophosphonates; D017905:Phosphites; D006859:Hydrogen; C012077:trifluoromethanesulfonic acid