title: Comparison between powdered gloves, powder-free gloves and hyaluronate/carboxymethylcellulose membrane on adhesion formation in a rat caecal serosal abrasion model.
abstract: OBJECTIVE
  Intraabdominal adhesion formation and prevention is one of the major conflicts of modern surgery. We aimed to determine the effects of powdered gloves versus powder-free gloves and hyaluronate/carboxymethylcellulose membrane (H/CMCm) in a rat caecal serosal abrasion model.
  
  
  METHODS
  Sixty wistar albino rats were subjected to a standardized lesion by caecal abrasion model. In group 1, the procedure was performed with sterile powdered gloves. In group 2, the procedure was performed with powder-free sterile gloves. The H/CMCm was applied directly to the abraded caecum in group 3. Formation of adhesions were determined on one half of the animals from each group on the 7th postoperative day, and on the other half on the 15th postoperative day.
  
  
  RESULTS
  There was a statistically significant difference between the adhesion scores on day 7 and 15 in groups 1 and 2 (p = 0.005, p = 0.007). There was no significant difference in adhesion scores on day 7 and 15 in group 3 (p = 0.145). The mean adhesion score was significantly higher in group 1 (powdered glove group) than group 2 (powder-free glove group) and group 3 (powder-free glove plus H/CMCm) on postoperative day 7 (p = 0.001). However, no significant difference was found between groups regarding adhesion scores on postoperative day 15 (p = 0.607). The comparisons of group 2 versus group 3, both on postoperative day 7 (p = 0.051) was not statistically significant, whereas a significant difference was detected between group 1 versus group 2 and group 3 on postoperative day 7 (p = 0.013, p = 0.001).
  
  
  CONCLUSIONS
  Our experiment shows that the use of powder-free gloves may be as beneficial as Seprafilm in preventing postoperative adhesion formation.
authors.affiliation: Department of Pediatric Surgery, Medical Faculty of Zonguldak Karaelmas University, Zonguldak, Turkey.
authors.forename: Varim
authors.initials: V
authors.lastname: Numanoğlu
authors.forename: Alper
authors.initials: A
authors.lastname: Cihan
authors.forename: Bülent
authors.initials: B
authors.lastname: Salman
authors.forename: Bülent Hamdi
authors.initials: BH
authors.lastname: Uçan
authors.forename: Guldeniz Karadeniz
authors.initials: GK
authors.lastname: Cakmak
authors.forename: Ali
authors.initials: A
authors.lastname: Cesur
authors.forename: Hakan
authors.initials: H
authors.lastname: Balbaloğlu
authors.forename: Mustafa N
authors.initials: MN
authors.lastname: Ilhan
mesh_terms: D000818:Animals; D002432:Cecum / Q000601:surgery*; D004195:Disease Models, Animal; D005932:Gloves, Surgical; D006820:Hyaluronic Acid; D008297:Male; D010532:Peritoneal Diseases / Q000209:etiology / Q000517:prevention & control*; D011183:Postoperative Complications; D011208:Powders; D051381:Rats; D017208:Rats, Wistar; D013213:Starch; D000267:Tissue Adhesions / Q000209:etiology / Q000517:prevention & control
chemical_list: D011208:Powders; C118198:Seprafilm; D006820:Hyaluronic Acid; D013213:Starch