Fundamentals of oxygen delivery.
Oxygen is vital to life. A series of steps are needed to transport oxygen from the lungs to the mitochondrion where the bulk of it is used for generation of energy. Understanding this pathway, which still remains to be properly characterized, will greatly aid both diagnosis and management of the hypoxic patient.
Yassin
James
J
Bloomsbury Institute of Intensive Care Medicine, University College London, London, UK.
Singer
Mervyn
M
D001692:Biological Transport / Q000502:physiology; D004734:Energy Metabolism / Q000502:physiology; D006801:Humans; D000860:Hypoxia / Q000175:diagnosis / Q000378:metabolism / Q000503:physiopathology* / Q000628:therapy; D019344:Lactic Acid / Q000378:metabolism; D008168:Lung / Q000378:metabolism*; D008928:Mitochondria / Q000378:metabolism*; D010100:Oxygen / Q000378:metabolism*
D019344:Lactic Acid; D010100:Oxygen