[Bronchial asthma attack with lactic acidosis and hypokalemia in a case receiving high dose inhalation of procaterol hydrochloride].
We report a case of bronchial asthma attack with lactic acidosis and hypokalemia in a patient receiving high-dose inhalation of procaterol hydrochloride. A 28-year-old man was transferred to our hospital because of adynamia, nausea and dyspnea. He had used inhaled procaterol hydrochloride with a pressurized metered dose inhaler about 20 times before admission. On admission, there were no signs of shock state or hypoxemia and laboratory data showed hypokalemia, hyperglycemia and metabolic acidosis with elevated anion gap. Lactic acidosis was identified as the reason for the metabolic acidosis with elevated anion gap. Lactic acidosis improved after 12 hours. Lactic acidosis due to high dose inhalation of procaterol hydrochloride was suggested.
Noma
Satoshi
S
Division of Respiratory Medicine, Respirology and Stress Care Center, Kagoshima University Hospital.
Kubota
Shingo
S
Matsukizono
Kazuya
K
Tanoue
Asako
A
Kumamoto
Tomohiro
T
Taira
Tetsuhiko
T
Mitsuyama
Hideo
H
Kawabata
Toshihumi
T
Suetsugu
Takayuki
T
Iwakaw
Jun
J
Koreed
Yoshimizu
Y
Matsuyama
Wataru
W
Mizuno
Keiko
K
Higashimoto
Ikkou
I
Osame
Mitsuhiro
M
Arimura
Kimiyoshi
K
D000140:Acidosis, Lactic / Q000139:chemically induced*; D000280:Administration, Inhalation; D000318:Adrenergic beta-Agonists / Q000008:administration & dosage / Q000009:adverse effects*; D000328:Adult; D001249:Asthma / Q000188:drug therapy*; D006801:Humans; D007008:Hypokalemia / Q000139:chemically induced*; D008297:Male; D017265:Procaterol / Q000008:administration & dosage / Q000009:adverse effects*
D000318:Adrenergic beta-Agonists; D017265:Procaterol