KIR2DL1 allelic diversity: four new alleles characterized in a bone marrow transplant population and three families.
Sequencing of PCR amplified genomic DNA including most of the coding region was used to identify killer cell immunoglobulin-like receptor 2DL1 alleles from three families and 77 bone marrow transplant patients and donors. Alleles 2DL1*00302 and *002 were frequently observed in addition to two other known alleles and four new alleles, 2DL1*00402, 2DL1*007, 2DL1*008, and 2DL1*009.
Hou
L H
LH
Department of Pediatrics, CW Bill Young Marrow Donor Recruitment and Research Program, Georgetown University Medical Center, Washington, DC 20057, USA.
Steiner
N K
NK
Chen
M
M
Belle
I
I
Ng
J
J
Hurley
C K
CK
D000483:Alleles; D016026:Bone Marrow Transplantation; D005190:Family; D005260:Female; D006801:Humans; D019520:Living Donors; D008297:Male; D011110:Polymorphism, Genetic; D011971:Receptors, Immunologic / Q000235:genetics*; D054342:Receptors, KIR2DL1; D014184:Transplantation, Homologous
C093100:KIR2DL1 protein, human; D011971:Receptors, Immunologic; D054342:Receptors, KIR2DL1