Psychotic disorder in a patient with central and extrapontine myelinolysis.
Central pontine and extrapontine myelinolysis (CPEM) are rare conditions usually associated with rapid correction of hyponatremia. Neurologic complications are the usual sequelae although neuropsychiatric features are rare. Described herein are unusual psychotic symptoms following CPEM and discussion of the likely pathogenesis and implications for treatment.
Lim
Leslie
L
Singapore General Hospital, Singapore. gdmlec@sgh.com.sg
Krystal
Andrew
A
D018687:Antidepressive Agents, Second-Generation / Q000627:therapeutic use; D000978:Antiparkinson Agents / Q000627:therapeutic use; D014150:Antipsychotic Agents / Q000627:therapeutic use; D001418:Baclofen / Q000627:therapeutic use; D005260:Female; D016666:Fluvoxamine / Q000627:therapeutic use; D018755:GABA Agonists / Q000627:therapeutic use; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D009069:Movement Disorders / Q000209:etiology; D017590:Myelinolysis, Central Pontine / Q000150:complications* / Q000473:pathology / Q000523:psychology*; D011618:Psychotic Disorders / Q000209:etiology* / Q000473:pathology / Q000523:psychology*; D011782:Quadriplegia / Q000209:etiology; D018967:Risperidone / Q000627:therapeutic use; D014282:Trihexyphenidyl / Q000627:therapeutic use
D018687:Antidepressive Agents, Second-Generation; D000978:Antiparkinson Agents; D014150:Antipsychotic Agents; D018755:GABA Agonists; D014282:Trihexyphenidyl; D001418:Baclofen; D018967:Risperidone; D016666:Fluvoxamine