title: [Clinical course and therapy of lymphomatoid papulosis. Experience with 17 cases and literature review].
abstract: Lymphomatoid papulosis is a rare disease with a worldwide incidence of 1.2 to 1.9 per 1 million. It affects all age groups with a peak incidence between 30 and 40 years and an apparent male predominance. Occurrence in childhood has also been described. Both the etiology and pathogenesis of the disease are unknown. The clinical presentation is extremely variable and frequently uncharacteristic. A papulonodular eruption, characterized by self-healing skin lesions appearing in crops can often be seen, particularly on extremities. We report on 17 patients, including 2 children. By detailing 6 cases we point out the variable morphologic manifestations, the different courses of disease and therapeutic options.
authors.affiliation: Hautklinik des Universitätsklinikums Düsseldorf, Moorenstrasse 5, 40225, Düsseldorf, Germany. korpusik@med.uni-duesseldorf.de
authors.forename: D
authors.initials: D
authors.lastname: Korpusik
authors.forename: T
authors.initials: T
authors.lastname: Ruzicka
mesh_terms: D000368:Aged; D001706:Biopsy; D002471:Cell Transformation, Neoplastic / Q000473:pathology; D002648:Child; D002675:Child, Preschool; D003937:Diagnosis, Differential; D004804:Eosinophils / Q000473:pathology; D005260:Female; D005500:Follow-Up Studies; D006644:Histiocytes / Q000473:pathology; D006801:Humans; D017730:Ki-1 Antigen / Q000032:analysis; D008214:Lymphocytes / Q000473:pathology; D017728:Lymphoma, Large-Cell, Anaplastic / Q000145:classification / Q000175:diagnosis / Q000473:pathology / Q000628:therapy; D017731:Lymphomatoid Papulosis / Q000145:classification / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D008297:Male; D008875:Middle Aged; D008938:Mitosis / Q000502:physiology; D009504:Neutrophils / Q000473:pathology; D012867:Skin / Q000473:pathology
chemical_list: D017730:Ki-1 Antigen