title: Novel 7- and 8-endo 2-indolylacyl radical cyclizations: efficient construction of azepino- and azocinoindoles.
abstract: Regioselective 7- and 8-endo cyclizations of selenoester derived 2-indolylacyl radicals upon amino tethered alkenes have been used to synthesize azepino[3,2-b]- and azocino[4,3-b]indoles, which are tricyclic subunits present in the indole alkaloids mersicarpine and apparicine, respectively.
authors.affiliation: Laboratory of Organic Chemistry, Faculty of Pharmacy, University of Barcelona, Barcelona 08028, Spain. bennasar@ub.edu
authors.forename: M-Lluïsa
authors.initials: ML
authors.lastname: Bennasar
authors.forename: Tomàs
authors.initials: T
authors.lastname: Roca
authors.forename: Davinia
authors.initials: D
authors.lastname: García-Díaz
mesh_terms: D001381:Azepines / Q000138:chemical synthesis*; D001392:Azocines / Q000138:chemical synthesis*; D003500:Cyclization; D007211:Indoles / Q000138:chemical synthesis*
chemical_list: D001381:Azepines; D001392:Azocines; D007211:Indoles