[Use of anti-thrombotic agents--monotherapy or combination and risk of upper gastrointestinal bleedings: a population-based case-control study. Secondary publication].
The clinical use of anti-thrombotic agents has shifted towards more aggressive therapy and towards regimes with more than one drug. Data on the risk of upper gastrointestinal bleedings (UGB) with combined anti-thrombotic therapy are scarce. In the period 2000 through 2004, 1,443 cases of serious UGB and 57,720 control subjects were identified in Funen County. Anti-thrombotic therapy is becoming increasingly aggressive. Combined anti-thrombotic therapy confers particular risk and is associated with high incidence rates of GI bleeding.
Hallas
Jesper
J
Syddansk Universitet, Afdelingen for Klinisk Farmakologi, IST, Forskningsenheden for almen medicin, Odense. jhallas@health.sdu.dk
Dall
Michael
M
Andries
Alin
A
Andersen
Birthe Søgaard
BS
Aalykke
Claus
C
Hansen
Jane Møller
JM
Andersen
Morten
M
Lassen
Annmarie Touborg
AT