Adverse events following immunization: perception and evidence.
OBJECTIVE
The aim of this article is to highlight the evidence on new and ongoing vaccine safety concerns in the light of several vaccines recently licensed and others made available and recommended more widely.


RESULTS
There is increasingly convincing epidemiologic and laboratory evidence against a causal relation of several alleged adverse events following immunization. The scientific framework to detect and investigate adverse events following immunization is increasingly robust.


CONCLUSIONS
Currently available vaccines are safe in immunocompetent individuals and there is no evidence to deviate from current immunization schedules.
Bonhoeffer
Jan
J
University Children's Hospital, Basel, Switzerland. jan.bonhoeffer@ukbb.ch
Heininger
Ulrich
U
D006801:Humans; D032541:Mass Vaccination / Q000009:adverse effects*; D016017:Odds Ratio; D011639:Public Opinion; D014611:Vaccination / Q000009:adverse effects*; D014612:Vaccines / Q000009:adverse effects*
D014612:Vaccines