Polyphenotypic peripheral neuroepithelioma occuring in the foot: a case report.
Peripheral neuroepithelioma of the soft tissues is an uncommon member of primitive neuroectodermal tumors. Divergent differentiation and polyphenotypia is known in peripheral neuroepithelioma. We report one such recurrent peripheral neuroepithelioma in an infant which was detected at one month of age, in the foot. Microscopically, it showed tumor cells in nests and lobules with abundant Homer-Wright rosettes. Immunohistochemically, tumor cells were immunoreactive for neural markers but also displayed an aberrant myoid phenotype. The prognostic implications of this anomalous phenotype are unclear as of now, but documentation of this is necessary for possible future references.
Bharadwaj
Reena
R
Department of Pathology, Armed Forces Medical College, Pune. prashantbharadwaj@hotmaiil.com
Pradhudesai
Shilpa
S
Patkar
Nikhil
N
Badhwar
Rajesh
R
Jambhekar
N A
NA
D015415:Biomarkers; D005528:Foot / Q000473:pathology; D005534:Foot Diseases / Q000175:diagnosis* / Q000473:pathology; D006651:Histocytochemistry; D006801:Humans; D007150:Immunohistochemistry; D007223:Infant; D018241:Neuroectodermal Tumors, Primitive, Peripheral / Q000175:diagnosis* / Q000473:pathology; D011379:Prognosis
D015415:Biomarkers