title: BCG pyelonephritis following intravesical therapy for transitional cell carcinoma.
abstract: Bacillus Calmette-Guerin (BCG) is a common intravesical agent utilized for superficial transitional cell carcinoma of the bladder. The potential for side effects and complications does exist secondary to the utilization of live attenuated bacteria. We present the case of a 70-year old male that developed BCG pyelonephritis and associated renal mass following the fifth of six weekly intravesical BCG therapies. The patient improved clinically and renal mass resolved following 3 months of isoniazid monotherapy without renal biopsy.
authors.affiliation: Department of Urology, Mayo Clinic Jacksonville, Jacksonville, Florida 32224, USA.
authors.forename: Jorge E
authors.initials: JE
authors.lastname: Garcia
authors.forename: David D
authors.initials: DD
authors.lastname: Thiel
authors.forename: Gregory A
authors.initials: GA
authors.lastname: Broderick
mesh_terms: D000283:Administration, Intravesical; D000368:Aged; D001500:BCG Vaccine / Q000008:administration & dosage / Q000009:adverse effects*; D002295:Carcinoma, Transitional Cell / Q000188:drug therapy*; D006801:Humans; D008297:Male; D009163:Mycobacterium bovis; D011704:Pyelonephritis / Q000209:etiology* / Q000382:microbiology; D014376:Tuberculosis / Q000209:etiology* / Q000382:microbiology; D001749:Urinary Bladder Neoplasms / Q000188:drug therapy*
chemical_list: D001500:BCG Vaccine