title: Recurrent central giant cell granuloma in the mandible: surgical treatment and dental implant restoration.
abstract: Central giant cell granuloma is an uncommon benign intraosseus lesion of jaws. Traditional treatment has been local curettage, although aggressive sub-types have a high tendency to recur. This patient report describes a recurrent central giant cell granuloma involving the body of the mandible in a 48-year-old-woman. Initial treatment of lesion consisted of curettage and peripheral ostectomy. When recurrence was detected one year later, an en bloc resection and defect regeneration with a composite bone graft of autogenous bone, xenograft, and autologous platelet-rich plasma was carried out. Adequate new bone formation was observed during follow-up of 24 months. Two dental implants were placed, and implant-supported prosthesis was constructed, providing a satisfactory dental restoration.
authors.affiliation: Faculty of Dentistry, Department of Oral and Maxillofacial Surgery, Virgen del Rocio University Hospital, University of Seville, Spain. pinfante@us.es
authors.forename: Pedro
authors.initials: P
authors.lastname: Infante Cossío
authors.forename: Rafael
authors.initials: R
authors.lastname: Martínez de Fuentes
authors.forename: Andrés
authors.initials: A
authors.lastname: Carranza Carranza
authors.forename: Daniel
authors.initials: D
authors.lastname: Torres Lagares
authors.forename: José Luis
authors.initials: JL
authors.lastname: Gutiérrez Pérez
mesh_terms: D005260:Female; D006101:Granuloma, Giant Cell / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D006801:Humans; D008336:Mandibular Diseases / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D008875:Middle Aged; D011859:Radiography