ACE Inhibitor in the treatment of cutaneous and lymphatic sarcoidosis.
Angiotensin-converting enzyme is used as a marker for sarcoid activity. We describe a case of remission of cutaneous and lymphatic sarcoidosis in a patient treated with an ACE inhibitor for congestive heart failure and hypertension; the remission has continued over 4 years of follow-up. Because this is a report of only one case, there is a possibility of sampling error. Whether the patient's remission in this case was a serendipitous spontaneous remission that happened to occur during ACE inhibitor therapy or whether ACE inhibitor therapy can play a role in the treatment of sarcoidosis needs to be determined in a large clinical trial.
Kaura
Vinod
V
Department of Medicine, Community Hospital of San Bernardino, San Bernardino, California 92411, USA. Clouds@aol.com
Kaura
Samantha H
SH
Kaura
Claire S
CS
D000806:Angiotensin-Converting Enzyme Inhibitors / Q000627:therapeutic use*; D001552:Benzazepines / Q000627:therapeutic use*; D002311:Cardiomyopathy, Dilated / Q000150:complications / Q000188:drug therapy; D005260:Female; D006801:Humans; D008875:Middle Aged; D012074:Remission Induction; D012075:Remission, Spontaneous; D012507:Sarcoidosis / Q000150:complications / Q000188:drug therapy*; D012871:Skin Diseases / Q000150:complications / Q000188:drug therapy*
D000806:Angiotensin-Converting Enzyme Inhibitors; D001552:Benzazepines; C044946:benazepril