Effects of dietary administration of plant-derived anthocyanin-rich colors to spontaneously hypertensive rats.
Anthocyanins have beneficial effects such as free radical scavenging activity. We investigated the effects of continuous administration of colors from purple corn (PCC), purple sweet potato (PSC) and red radish (RRC) to spontaneously hypertensive rats (SHR). These are rich in anthocyanins. Animals were fed with diets containing PCC, PSC or RRC (1 mass% of diets) for 15 wk. While the body weight and the daily food intake of administered rats were not different from those of the non-administered control rats through the experimental period, the blood pressure and the heart rate of SHR administered each color decreased as compared to the control group from the early stage of administration. These results suggest that plant-derived colors containing anthocyanins have anti-hypertensive effects on hypertensive animals.
Shindo
Makoto
M
Department of Animal Science, Faculty of Agriculture, Okayama University, Okayama 700-8530, Japan.
Kasai
Toshikazu
T
Abe
Asaki
A
Kondo
Yasuhiro
Y
D000704:Analysis of Variance; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000494:pharmacology; D000818:Animals; D000872:Anthocyanins / Q000494:pharmacology*; D001794:Blood Pressure / Q000187:drug effects; D001835:Body Weight / Q000187:drug effects; D003116:Color; D004195:Disease Models, Animal; D004435:Eating; D018682:GABA Agents / Q000494:pharmacology; D006339:Heart Rate / Q000187:drug effects; D006973:Hypertension / Q000503:physiopathology / Q000517:prevention & control*; D027723:Ipomoea batatas; D008297:Male; D031224:Raphanus; D051381:Rats; D011918:Rats, Inbred SHR; D003313:Zea mays; D005680:gamma-Aminobutyric Acid / Q000494:pharmacology
D000806:Angiotensin-Converting Enzyme Inhibitors; D000872:Anthocyanins; D018682:GABA Agents; D005680:gamma-Aminobutyric Acid