Design, synthesis, and structural studies on potent biaryl inhibitors of type II dehydroquinases.
Payne
Richard J
RJ
Department of Chemistry, University of Cambridge, Lensfield Road, CB2 1EW, Cambridge, UK.
Riboldi-Tunnicliffe
Alan
A
Kerbarh
Olivier
O
Abell
Andrew D
AD
Lapthorn
Adrian J
AJ
Abell
Chris
C
D001665:Binding Sites; D001643:Bridged Bicyclo Compounds / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D015195:Drug Design; D004791:Enzyme Inhibitors / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D016480:Helicobacter pylori / Q000201:enzymology; D006836:Hydro-Lyases; D008958:Models, Molecular; D015394:Molecular Structure; D009169:Mycobacterium tuberculosis / Q000201:enzymology; D048372:Streptomyces coelicolor / Q000201:enzymology
D001643:Bridged Bicyclo Compounds; D004791:Enzyme Inhibitors; D006836:Hydro-Lyases; C020000:3-dehydroquinate dehydratase