Medication adherence in heart failure.
Non-adherence with medical regimens in heart failure is a significant challenge and serves as a major reason that favorable outcomes associated with various therapies evaluated in clinical trials have not translated to the so-called real-world setting. Non-adherence has complex influences and is clearly associated with poorer outcomes. The approaches that are used or have been proposed to improve drug-taking behavior, such as in-hospital initiation of therapy, simplification of dosing regimens through adoption of combination and long-acting formulations, and improvements in provider-patient communication, are reviewed.
Hauptman
Paul J
PJ
Division of Cardiology, Saint Louis University School of Medicine, St. Louis, Missouri, USA. hauptmpj@slu.edu
D002317:Cardiovascular Agents / Q000627:therapeutic use*; D004334:Drug Administration Schedule; D004338:Drug Combinations; D006333:Heart Failure / Q000188:drug therapy* / Q000523:psychology*; D006801:Humans; D010349:Patient Compliance; D010817:Physician-Patient Relations; D016896:Treatment Outcome
D002317:Cardiovascular Agents; D004338:Drug Combinations