title: Alterations of blood glucose homeostasis in critically ill children - hyperglycemia.
abstract: Hyperglycemia is common in critically ill children. It does not appear to be associated with a particular diagnostic category but is significantly associated with the severity of illness. Severe hyperglycemia may be associated with complications, this in turn could result in end-organ dysfunction. A prospective, randomized trial of strict glycemic control in this subset of critically ill children who are at high risk of mortality is both warranted and feasible. Continuous insulin infusion can rapidly and safely improve intravenous glucose tolerance.
authors.affiliation: Upper Silesia Mother and Child Health Center, Katowice. em.buczkowski@pro.onet.pl
authors.forename: Ewa
authors.initials: E
authors.lastname: Otto-Buczkowska
authors.forename: Tomasz
authors.initials: T
authors.lastname: Dworzecki
authors.forename: Urszula
authors.initials: U
authors.lastname: Mazur
mesh_terms: D001786:Blood Glucose / Q000378:metabolism*; D002648:Child; D015897:Comorbidity; D003422:Critical Care; D016638:Critical Illness / Q000401:mortality / Q000628:therapy*; D006706:Homeostasis / Q000187:drug effects* / Q000502:physiology; D006801:Humans; D006943:Hyperglycemia / Q000188:drug therapy / Q000453:epidemiology / Q000503:physiopathology*; D007004:Hypoglycemic Agents / Q000627:therapeutic use*; D007328:Insulin / Q000008:administration & dosage / Q000627:therapeutic use*; D007333:Insulin Resistance; D015278:Intensive Care Units, Pediatric; D017063:Outcome Assessment, Health Care; D016032:Randomized Controlled Trials as Topic; D012307:Risk Factors; D012720:Severity of Illness Index; D013312:Stress, Physiological / Q000378:metabolism
chemical_list: D001786:Blood Glucose; D007004:Hypoglycemic Agents; D007328:Insulin