title: Articaine and paresthesia: epidemiological studies.
abstract: Permanent paresthesia following a local anesthetic injection is a possible adverse event. Epidemiological studies have suggested that the 4% solutions used in dentistry, namely prilocaine and articaine, are more highly associated with this occurrence. This article reviews the epidemiological evidence regarding articaine and paresthesia.
authors.affiliation: Faculty of Dentistry, Department of Pharmacology, University of Toronto. daniel.haas@utoronto.ca
authors.forename: Daniel A
authors.initials: DA
authors.lastname: Haas
mesh_terms: D000766:Anesthesia, Dental / Q000009:adverse effects* / Q000379:methods; D000779:Anesthetics, Local / Q000009:adverse effects*; D002355:Carticaine / Q000009:adverse effects*; D004305:Dose-Response Relationship, Drug; D020220:Facial Nerve Injuries / Q000139:chemically induced; D006801:Humans; D010292:Paresthesia / Q000139:chemically induced*; D012996:Solutions; D013997:Time Factors
chemical_list: D000779:Anesthetics, Local; D012996:Solutions; D002355:Carticaine