[Prevalence of Helicobacter pylori CaGa strains and peptic ulcer in the population of Eastern Siberia].
OBJECTIVE
To study prevalence of Helicobacter pylori (Hp) CagA strains and ulcer disease in native population of eastern Siberia and migrants.


METHODS
Epidemiological screening of Hp CagA strains and ulcer disease was performed by cross-sectional method in population of Evenkia, Khakassia, Tuva. Fibrogastroduodenoscopy was made in 3602 examinees; IgG of CagA Hp was detected in the sera of 2472 patients with entyme immunoassay.


RESULTS
Prevalence of ulcer was higher in Europeans than in Mongoloids. Detectability of CagA Hp was 36.5% among khakas population, 43.8% among evenks, 60.1% among tyvin population, 59.8% among European population. In khakas and tyva population with ulcer CagA Hp incidence was higher than in healthy subjects. CONCLUSION. CagA HP is associated with ulcer in mongoloid population. This was not confirmed for European populatioin of the Eastern Siberia.
Tsukanov
V V
VV
Barkalov
S V
SV
Tonkikh
Iu L
IuL
Shtygasheva
O V
OV
Barmakov
A E
AE
Bronnikova
E P
EP
Amel'chugova
O S
OS
D000328:Adult; D005260:Female; D014943:Global Health; D016481:Helicobacter Infections / Q000453:epidemiology / Q000276:immunology / Q000382:microbiology; D016480:Helicobacter pylori / Q000145:classification* / Q000302:isolation & purification*; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood / Q000276:immunology*; D015994:Incidence; D008297:Male; D011159:Population Surveillance / Q000379:methods; D015995:Prevalence; D012800:Siberia / Q000453:epidemiology
D007074:Immunoglobulin G