title: Postoperative complications and mortality in older patients having non-cardiac surgery at three Melbourne teaching hospitals.
abstract: OBJECTIVE
  To determine the incidence of postoperative complications, including 30-day mortality rate, and need for intensive care unit (ICU) admission in older patients after non-cardiac surgery.
  
  
  METHODS
  Prospective observational study of all patients aged 70 years or older having elective and non-elective, non-cardiac surgery, and staying at least 1 night after surgery in one of three Melbourne teaching hospitals, June to September 2004.
  
  
  METHODS
  Postoperative complications and 30-day mortality rate.
  
  
  RESULTS
  1102 consecutive patients were audited in mid 2004; 70% had pre-existing comorbidities. The 30-day mortality rate was 6%; 19% had postoperative complications; and 20% of patients spent at least 1 night in ICU. On multivariate analysis, preoperative factors associated with 30-day mortality included age (odds ratio [OR], 1.09 per year over 70 years; 95% CI, 1.04-1.13; P < 0.001); increasing severity of systemic disease (American Society of Anesthesiologists physical status classification) (OR, 2.53; 95% CI, 1.65-3.86; P < 0.001); and albumin level < 30 g/L (OR, 2.23; 95% CI, 1.09-4.57; P = 0.03). Postoperative factors associated with 30-day mortality were unplanned ICU admission (OR, 3.95; 95% CI, 1.63-9.55; P = 0.003); sepsis (OR, 2.75; 95% CI, 1.17-6.47; P = 0.02); and acute renal impairment (OR, 2.40; 95% CI, 1.06-5.41; P = 0.04). Thoracic surgery was the only surgical specialty significantly associated with mortality (OR, 3.96; 95% CI, 1.44-9.10; P = 0.008) in the multivariate analysis.
  
  
  CONCLUSIONS
  Older patients having surgery had high rates of comorbidities and postoperative complications, placing considerable demands on critical care services. Patient factors were often stronger predictors of mortality than the type of surgery.
authors.affiliation: Austin Health, Melbourne, Victoria, Australia.
authors.forename: Larry
authors.initials: L
authors.lastname: McNicol
authors.forename: David A
authors.initials: DA
authors.lastname: Story
authors.forename: Kate
authors.initials: K
authors.lastname: Leslie
authors.forename: Paul S
authors.initials: PS
authors.lastname: Myles
authors.forename: Michael
authors.initials: M
authors.lastname: Fink
authors.forename: Andrew C
authors.initials: AC
authors.lastname: Shelton
authors.forename: Ornella
authors.initials: O
authors.lastname: Clavisi
authors.forename: Stephanie J
authors.initials: SJ
authors.lastname: Poustie
mesh_terms: D058186:Acute Kidney Injury / Q000401:mortality; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D001315:Australia / Q000453:epidemiology; D005260:Female; D017052:Hospital Mortality; D006784:Hospitals, Teaching; D006801:Humans; D007362:Intensive Care Units / Q000706:statistics & numerical data; D008297:Male; D015999:Multivariate Analysis; D011183:Postoperative Complications / Q000453:epidemiology*; D011446:Prospective Studies; D018805:Sepsis / Q000401:mortality; D012709:Serum Albumin / Q000032:analysis; D012720:Severity of Illness Index; D013514:Surgical Procedures, Operative / Q000401:mortality*
chemical_list: D012709:Serum Albumin