title: An efficient synthesis of pyrido[2,3-d]pyrimidine derivatives and related compounds under ultrasound irradiation without catalyst.
abstract: A series of pyrido[2,3-d]pyrimidine derivatives and related compounds were synthesized via the condensation reaction of an aldehyde, 2,6-diaminopyrimidine-4(3H)-one and either tetronic acid or 1,3-indanedione under ultrasonic irradiation without catalyst. This protocol has the advantages of higher yields, lower cost and convenient procedure.
authors.affiliation: Department of Chemistry, Xuzhou Normal University, Key Laboratory of Biotechnology for Medicinal Plant, Xuzhou, Jiangsu 221116, PR China. laotu2001@263.net
authors.forename: Shujiang
authors.initials: S
authors.lastname: Tu
authors.forename: Longji
authors.initials: L
authors.lastname: Cao
authors.forename: Yan
authors.initials: Y
authors.lastname: Zhang
authors.forename: Qingqing
authors.initials: Q
authors.lastname: Shao
authors.forename: Dianxiang
authors.initials: D
authors.lastname: Zhou
authors.forename: Chunmei
authors.initials: C
authors.lastname: Li
mesh_terms: D000447:Aldehydes / Q000737:chemistry; D002384:Catalysis; D015195:Drug Design; D004791:Enzyme Inhibitors; D019855:Ethylene Glycol / Q000737:chemistry; D005663:Furans / Q000737:chemistry; D007189:Indans / Q000737:chemistry; D008956:Models, Chemical; D015394:Molecular Structure; D011728:Pyridones; D011743:Pyrimidines / Q000138:chemical synthesis* / Q000737:chemistry*; D012997:Solvents / Q000737:chemistry; D014465:Ultrasonics
chemical_list: C413384:1,2-indanedione; D000447:Aldehydes; D004791:Enzyme Inhibitors; D005663:Furans; D007189:Indans; C115711:PD 173074; D011728:Pyridones; D011743:Pyrimidines; D012997:Solvents; D019855:Ethylene Glycol; C003422:tetronic acid