Libaffy: software for processing Affymetrix GeneChip data.
CONCLUSIONS
Affymetrix GeneChip microarrays are increasingly used in gene expression studies and in greater number. A software library was developed that supports Affymetrix file formats and implements two popular summary algorithms (MAS5.0 and RMA). The library is modular in design for integration into larger systems and processing pipelines. Additionally, a graphical interface (GENE) was developed to allow end-user access to the functionality within the library.


BACKGROUND
libaffy is free to use under the GNU GPL license. The source code and Windows binaries can be freely accessed from the website http://src.moffitt.usf.edu/libaffy. Additional API documentation and user manual are available.
Eschrich
Steven A
SA
H. Lee Moffitt Cancer Center and Research Institute, University of South Florida, Tampa, FL 33612, USA. Steven.Eschrich@moffitt.org
Hoerter
Andrew M
AM
D000465:Algorithms; D019295:Computational Biology / Q000379:methods*; D020869:Gene Expression Profiling / Q000379:methods; D020411:Oligonucleotide Array Sequence Analysis / Q000379:methods*; D012984:Software; D014584:User-Computer Interface