title: Effect of uvulopalatopharyngoplasty on work of breathing during wakefulness in obstructive sleep apnea syndrome.
abstract: OBJECTIVE
  We evaluated the effects of uvulopalatopharyngoplasty (UPPP) on the work of breathing (WOB) in obstructive sleep apnea syndrome (OSAS).
  
  
  METHODS
  Fifteen healthy subjects and 30 subjects with OSAS who desired UPPP were prospectively enrolled. All underwent measurement of WOB while awake as well as in a sleep study. These studies were repeated 3 months after UPPP in the patients with OSAS.
  
  
  RESULTS
  In OSAS before UPPP, the WOB while supine was increased above that of normal subjects. After UPPP, the WOB while supine remained elevated in those whose OSAS did not respond to surgery, and it returned to normal levels in patients whose OSAS improved after UPPP.
  
  
  CONCLUSIONS
  Abnormal WOB in patients with OSAS returns to normal if UPPP results in amelioration of OSAS.
authors.affiliation: Chest Division, Department of Internal Medicine, Mackay Memorial Hospital, Taipei, Taiwan.
authors.forename: Ching-Chi
authors.initials: CC
authors.lastname: Lin
authors.forename: Kuo-Sheng
authors.initials: KS
authors.lastname: Lee
authors.forename: Ying-Piao
authors.initials: YP
authors.lastname: Wang
authors.forename: Wen-Yeh
authors.initials: WY
authors.lastname: Hsieh
authors.forename: Sheng-Yeh
authors.initials: SY
authors.lastname: Shen
authors.forename: Chung-Hsin
authors.initials: CH
authors.lastname: Chiu
authors.forename: Shwu-Fang
authors.initials: SF
authors.lastname: Liaw
mesh_terms: D000328:Adult; D004585:Electrooculography; D005260:Female; D006801:Humans; D008297:Male; D013517:Otorhinolaryngologic Surgical Procedures / Q000379:methods*; D010614:Pharynx / Q000601:surgery*; D010991:Plethysmography; D017286:Polysomnography; D019651:Plastic Surgery Procedures / Q000379:methods*; D012720:Severity of Illness Index; D020181:Sleep Apnea, Obstructive / Q000503:physiopathology / Q000601:surgery*; D016896:Treatment Outcome; D014609:Uvula / Q000601:surgery*; D014851:Wakefulness / Q000502:physiology*; D014939:Work of Breathing / Q000502:physiology*