title: Complexations of Hg(CN)(2) with imidazolidine-2-thione and its derivatives: solid state, solution NMR and antimicrobial activity studies.
abstract: The preparation and characterization of new mercuric complexes of formula L(2)Hg(CN)(2) with L being imidazolidine-2-thione (Imt) and its substituted derivatives, 1,3-diazinane-2-thione (Diaz), 1,3-diazipane-2-thione (Diap), are described. The solution and solid-state (13)C NMR show a significant shift of the CS carbon resonance of the ligands, while the other resonances are relatively unaffected, indicating that most likely the solid-state structure is maintained in solution as well. The principal components of the (199)Hg shielding tensors were determined from solid-state NMR data. Antimicrobial activity studies of the free ligands and their complexes show that ligands exhibit substantial antibacterial activities compare to their Hg(II) complexes.
authors.affiliation: Department of Chemistry, King Fahd University of Petroleum and Minerals, Dhahran, Saudi Arabia. miwazeer@kfupm.edu.sa
authors.forename: Mohamed I M
authors.initials: MI
authors.lastname: Wazeer
authors.forename: Anvarhusein A
authors.initials: AA
authors.lastname: Isab
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects; D002247:Carbon Isotopes; D003486:Cyanides / Q000737:chemistry*; D005031:Ethylenethiourea; D048289:Imidazolidines / Q000737:chemistry* / Q000494:pharmacology*; D008024:Ligands; D009682:Magnetic Resonance Spectroscopy; D017669:Mercury Compounds / Q000737:chemistry*; D008826:Microbial Sensitivity Tests; D011522:Protons; D012996:Solutions; D013055:Spectrophotometry, Infrared; D013871:Thiones / Q000737:chemistry* / Q000494:pharmacology*
chemical_list: D000900:Anti-Bacterial Agents; D002247:Carbon Isotopes; D003486:Cyanides; D048289:Imidazolidines; D008024:Ligands; D017669:Mercury Compounds; D011522:Protons; D012996:Solutions; D013871:Thiones; D005031:Ethylenethiourea; C040189:mercuric cyanide