title: Polyphenotypic peripheral neuroepithelioma occuring in the foot: a case report.
abstract: Peripheral neuroepithelioma of the soft tissues is an uncommon member of primitive neuroectodermal tumors. Divergent differentiation and polyphenotypia is known in peripheral neuroepithelioma. We report one such recurrent peripheral neuroepithelioma in an infant which was detected at one month of age, in the foot. Microscopically, it showed tumor cells in nests and lobules with abundant Homer-Wright rosettes. Immunohistochemically, tumor cells were immunoreactive for neural markers but also displayed an aberrant myoid phenotype. The prognostic implications of this anomalous phenotype are unclear as of now, but documentation of this is necessary for possible future references.
authors.affiliation: Department of Pathology, Armed Forces Medical College, Pune. prashantbharadwaj@hotmaiil.com
authors.forename: Reena
authors.initials: R
authors.lastname: Bharadwaj
authors.forename: Shilpa
authors.initials: S
authors.lastname: Pradhudesai
authors.forename: Nikhil
authors.initials: N
authors.lastname: Patkar
authors.forename: Rajesh
authors.initials: R
authors.lastname: Badhwar
authors.forename: N A
authors.initials: NA
authors.lastname: Jambhekar
mesh_terms: D015415:Biomarkers; D005528:Foot / Q000473:pathology; D005534:Foot Diseases / Q000175:diagnosis* / Q000473:pathology; D006651:Histocytochemistry; D006801:Humans; D007150:Immunohistochemistry; D007223:Infant; D018241:Neuroectodermal Tumors, Primitive, Peripheral / Q000175:diagnosis* / Q000473:pathology; D011379:Prognosis
chemical_list: D015415:Biomarkers