Isolation and characterization of biogenetically related highly oxygenated nortriterpenoids from Schisandra chinensis.
Pre-schisanartanin (1) and schindilactones A-C (2-4) were isolated from Schisandra chinensis. Among them, compound 1 had an unprecedented carbon skeleton. More importantly, the structure features of this compound provided new insight into the biosynthesis of triterpenoids with schisanartane skeleton. Their structures were determined by extensive spectroscopic analysis, single-crystal X-ray diffraction, and on the basis of the absolute structure of one related nortriterpenoid (5), which was determined for the first time by a modified Mosher method.
Huang
Sheng-Xiong
SX
State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, People's Republic of China.
Li
Rong-Tao
RT
Liu
Jing-Ping
JP
Lu
Yang
Y
Chang
Ying
Y
Lei
Chun
C
Xiao
Wei-Lie
WL
Yang
Li-Bin
LB
Zheng
Qi-Tai
QT
Sun
Han-Dong
HD
D008958:Models, Molecular; D015394:Molecular Structure; D010100:Oxygen / Q000032:analysis / Q000737:chemistry*; D032141:Schisandra / Q000737:chemistry*; D014315:Triterpenes / Q000737:chemistry*
D014315:Triterpenes; D010100:Oxygen