title: Efficacy and safety of hormonal treatment of cryptorchidism: current state of the art.
abstract: Meta-analyses of randomised trials using hCG or GnRH for treatment on testicular descent show in most studies overall efficacy of about 20%, less if retractile testes were excluded. In recent years a number of potentially serious side effects have been reported.
  
  
  CONCLUSIONS
  Considering the efficacy and the possible side effects of the hormonal treatment, the general use of hCG and GnRH in the treatment of cryptorchidism cannot be further recommended.
authors.affiliation: Children's Medical Center, Landspitali University Hospital, 101 Reykjavik, Iceland. arniv@landspitali.is
authors.forename: Arni V
authors.initials: AV
authors.lastname: Thorsson
authors.forename: Peter
authors.initials: P
authors.lastname: Christiansen
authors.forename: Martin
authors.initials: M
authors.lastname: Ritzén
mesh_terms: D006063:Chorionic Gonadotropin / Q000009:adverse effects / Q000627:therapeutic use; D003456:Cryptorchidism / Q000188:drug therapy*; D006801:Humans; D008297:Male; D015201:Meta-Analysis as Topic; D016032:Randomized Controlled Trials as Topic
chemical_list: D006063:Chorionic Gonadotropin