title: The structural basis of glycosidase inhibition by five-membered iminocyclitols: the clan a glycoside hydrolase endoglycoceramidase as a model system.
authors.affiliation: Department of Biochemistry and Molecular Biology, University of British Columbia, 2350 Health Sciences Mall, Vancouver, BC V6T 1Z3, Canada.
authors.forename: Matthew E C
authors.initials: ME
authors.lastname: Caines
authors.forename: Susan M
authors.initials: SM
authors.lastname: Hancock
authors.forename: Chris A
authors.initials: CA
authors.lastname: Tarling
authors.forename: Tanja M
authors.initials: TM
authors.lastname: Wrodnigg
authors.forename: Robert V
authors.initials: RV
authors.lastname: Stick
authors.forename: Arnold E
authors.initials: AE
authors.lastname: Stütz
authors.forename: Andrea
authors.initials: A
authors.lastname: Vasella
authors.forename: Stephen G
authors.initials: SG
authors.lastname: Withers
authors.forename: Natalie C J
authors.initials: NC
authors.lastname: Strynadka
mesh_terms: D004791:Enzyme Inhibitors / Q000737:chemistry; D006026:Glycoside Hydrolases / Q000037:antagonists & inhibitors*; D050111:Imino Sugars / Q000737:chemistry / Q000494:pharmacology*; D011485:Protein Binding; D055672:Static Electricity; D013329:Structure-Activity Relationship; D014867:Water
chemical_list: D004791:Enzyme Inhibitors; D050111:Imino Sugars; D014867:Water; D006026:Glycoside Hydrolases; C050427:endoglycoceramidase