title: Severe systemic adverse reaction to proton pump inhibitors in an infant.
abstract: Episodes of respiratory distress with chest retraction and wheezing, sometimes associated with facial edema, were noted after administering the proton pump inhibitors omeprazole and esomeprazole in an infant with gastroesophageal reflux. The disturbances relieved dramatically after withdrawing the proton pump inhibitor.
authors.affiliation: Division of Pediatric Surgery, Ospedale San Giovanni, Bellinzona, Switzerland.
authors.forename: Emanuele
authors.initials: E
authors.lastname: Baldassarre
authors.forename: Mario Mendoza
authors.initials: MM
authors.lastname: Sagaon
authors.forename: Alessandra
authors.initials: A
authors.lastname: Ferrarini
authors.forename: Mario G
authors.initials: MG
authors.lastname: Bianchetti
mesh_terms: D004791:Enzyme Inhibitors / Q000009:adverse effects*; D064098:Esomeprazole; D005260:Female; D005764:Gastroesophageal Reflux / Q000188:drug therapy / Q000601:surgery; D006801:Humans; D007223:Infant; D008171:Lung Diseases / Q000139:chemically induced* / Q000175:diagnosis; D009853:Omeprazole / Q000009:adverse effects*; D054328:Proton Pump Inhibitors; D012135:Respiratory Sounds / Q000209:etiology
chemical_list: D004791:Enzyme Inhibitors; D054328:Proton Pump Inhibitors; D009853:Omeprazole; D064098:Esomeprazole