Antioxidant responses in the nereidid Laeonereis acuta (Annelida, Polychaeta) after cadmium exposure.
The objective of this study was to evaluate the effects of the exposure to cadmium on the antioxidant responses in the polychaeta Laeonereis acuta. The worms were submitted to 0, 5, and 100 microg of Cd/L during a period of test of 7 days. Cadmium was significantly (p<0.05) accumulated in L. acuta in both concentrations assayed, but the concentration of reactive oxygen and nitrogen species (RONS) increased (p<0.05) only in the group submitted to the highest concentration of cadmium (100 microg/L). At this concentration, a decrease in the activity of the superoxide dismutase and an increase of glutathione-S-transferase activity (p<0.05) was observed. The levels of both lipid peroxides and the activities of catalase and glutathione peroxidase were not affected (p>0.05) by the exposition to cadmium. Thus, cadmium can augment RONS levels and can interfere with the antioxidant defense system of the polychaete L. acuta, although cadmium does not directly induce oxidative stress unlike copper and iron.
Sandrini
Juliana Zomer
JZ
Programa de Pós-Graduação em Ciências Fisiológicas-Fisiologia Animal Comparada-PPGCF-FAC, FURG, Brazil.
Lima
Juliane Ventura
JV
Regoli
Francesco
F
Fattorini
Daniele
D
Notti
Alessandra
A
Marins
Luis Fernando
LF
Monserrat
José María
JM
D000818:Animals; D000975:Antioxidants / Q000378:metabolism*; D002104:Cadmium / Q000633:toxicity*; D002374:Catalase / Q000378:metabolism; D004785:Environmental Pollutants / Q000633:toxicity*; D005979:Glutathione Peroxidase / Q000378:metabolism; D005982:Glutathione Transferase / Q000378:metabolism; D008054:Lipid Peroxides / Q000378:metabolism; D011077:Polychaeta / Q000187:drug effects* / Q000378:metabolism; D026361:Reactive Nitrogen Species / Q000378:metabolism; D017382:Reactive Oxygen Species / Q000378:metabolism; D013482:Superoxide Dismutase / Q000378:metabolism
D000975:Antioxidants; D004785:Environmental Pollutants; D008054:Lipid Peroxides; D026361:Reactive Nitrogen Species; D017382:Reactive Oxygen Species; D002104:Cadmium; D002374:Catalase; D005979:Glutathione Peroxidase; D013482:Superoxide Dismutase; D005982:Glutathione Transferase