Color Doppler sonographic analysis of uterine and ovarian artery blood flow in women with polycystic ovary syndrome.
OBJECTIVE
To study the blood flow patterns of utero-ovarian circulation in polycystic ovary syndrome (PCOS) and to assess their relationship with clinical, metabolic, and hormonal data.


METHODS
Forty-three women with PCOS and 43 age-matched healthy controls underwent Doppler examination of the utero-ovarian circulation in the follicular phase. Demographic, hormonal, and metabolic parameters were determined. Student's t-test, chi(2)-test, and Spearman correlation test were used for statistical analysis.


RESULTS
The ovarian artery pulsatility index (PI), resistance index (RI), and SD ratios were significantly lower in PCOS than in controls on the right side (p < 0.001, p = 0.02, p = 0.001, respectively) as well as on the left side (p < 0.001, p < 0.001, p < 0.001, respectively). The uterine artery systolic/diastolic (S/D) ratio was higher on both sides (p = 0.01) and the PI was higher on the left side (p = 0.02) in PCOS than in controls. The right uterine artery PI was positively correlated with luteinizing hormone and hemoglobin (r = 0.417, p = 0.043; r = 0.427, p = 0.033, respectively), the right uterine artery S/D was positively correlated with body mass index (r = 0.479, p = 0.015), and the left uterine artery PI was positively correlated with insulin (r = 0.458, p = 0.021).


CONCLUSIONS
Doppler sonography of the utero-ovarian circulation may contribute to the evaluation of PCOS patients and a better understanding of the pathophysiology of this syndrome.
Ozkan
Sebiha
S
Department of Obstetrics and Gynecology, Kocaeli University School of Medicine, Tüpraş Sitesi, Güney Mahallesi, 7 Sokak, No. 20, Kat. 2, 41780, Körfez, Kocaeli, Turkey.
Vural
Birol
B
Calişkan
Eray
E
Bodur
Harika
H
Türköz
Erkan
E
Vural
Füsun
F
D000328:Adult; D001158:Arteries / Q000000981:diagnostic imaging; D001794:Blood Pressure / Q000502:physiology; D015992:Body Mass Index; D016022:Case-Control Studies; D005260:Female; D005498:Follicular Phase / Q000502:physiology; D006454:Hemoglobins / Q000032:analysis; D006801:Humans; D007328:Insulin / Q000097:blood; D007986:Luteinizing Hormone / Q000097:blood; D010053:Ovary / Q000098:blood supply* / Q000000981:diagnostic imaging; D011085:Polycystic Ovary Syndrome / Q000000981:diagnostic imaging* / Q000503:physiopathology; D011446:Prospective Studies; D011673:Pulsatile Flow / Q000502:physiology; D012039:Regional Blood Flow / Q000502:physiology; D012738:Sex Hormone-Binding Globulin / Q000032:analysis; D018615:Ultrasonography, Doppler, Color; D018616:Ultrasonography, Doppler, Duplex; D014599:Uterus / Q000098:blood supply* / Q000000981:diagnostic imaging; D014655:Vascular Resistance / Q000502:physiology
D006454:Hemoglobins; D007328:Insulin; D012738:Sex Hormone-Binding Globulin; D007986:Luteinizing Hormone