Smart nanomaterials inspired by biology: dynamic assembly of error-free nanomaterials in response to multiple chemical and biological stimuli.
Three-dimensional functional nanoscale assembly requires not only self-assembly of individual nanomaterials responsive to external stimuli, such as temperature, light, and concentrations, but also directed assembly of many different nanomaterials in one-pot responsive to multiple internal stimuli signaling the needs for such materials at a specific location and a particular time. The use of functional DNA (DNAzymes, aptamers, and aptazymes) to meet these challenges is reviewed. In addition, a biology-inspired proof-reading and error correction method is introduced to cope with errors in nanomaterials assembly.
Lu
Yi
Y
Department of Chemistry and Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana--Champaign, Urbana, Illinois 61801, USA. yi-lu@uiuc.edu
Liu
Juewen
J
D052157:Aptamers, Nucleotide / Q000737:chemistry; D001483:Base Sequence; D032701:Biomimetics / Q000379:methods*; D001709:Biotechnology / Q000379:methods*; D004247:DNA / Q000737:chemistry*; D021881:DNA, Catalytic / Q000737:chemistry; D004789:Enzyme Activation; D008027:Light; D049329:Nanostructures / Q000737:chemistry*; D013696:Temperature; D013997:Time Factors
D052157:Aptamers, Nucleotide; D021881:DNA, Catalytic; D004247:DNA