title: Breast malignant phyllodes tumour metastasising to soft tissues of oral cavity.
abstract: Metastases from infraclavicular neoplasms to the oral cavity are rare, and the anatomical structures most frequently affected are the maxillae. The primary sites that develop metastases to head and neck include lung, breast, liver, thyroid gland, kidney and melanomas, among others. The breast is one of the usual primary regions that can present them. In the literature, most metastases to these regions correspond to squamous cell carcinomas and adenocarcinomas; few studies report other type of neoplasms such as phyllodes tumour (PT) that present this behaviour. The importance of identifying metastatic disease to the oral cavity, be it as the first manifestation of a neoplasm from unknown origin or as a development in the course of the disease, is that it allows determination of adequate treatment, which has an effect on the patient's prognosis. The usual behaviour of PT is frequent recurrence and, when metastases are present, these are to lungs and bone. Two cases of malignant PT metastasising to tongue and lip are presented, as well as a review of the literature.
authors.affiliation: Division of Pathology, National Institute of Cancerology, Tlalpan, México, D.F.
authors.forename: M de Lourdes
authors.initials: Mde L
authors.lastname: Suárez Roa
authors.forename: L M
authors.initials: LM
authors.lastname: Ruiz Godoy Rivera
authors.forename: T
authors.initials: T
authors.lastname: Vela Chávez
authors.forename: M
authors.initials: M
authors.lastname: Pérez Sánchez
authors.forename: A
authors.initials: A
authors.lastname: Meneses García
mesh_terms: D000328:Adult; D001943:Breast Neoplasms / Q000175:diagnosis / Q000188:drug therapy / Q000401:mortality / Q000473:pathology / Q000601:surgery; D003131:Combined Modality Therapy; D018450:Disease Progression; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008046:Lip / Q000473:pathology; D008048:Lip Neoplasms / Q000175:diagnosis / Q000401:mortality / Q000473:pathology / Q000556:secondary*; D015411:Mastectomy, Modified Radical; D015412:Mastectomy, Segmental; D008875:Middle Aged; D009362:Neoplasm Metastasis; D003557:Phyllodes Tumor / Q000175:diagnosis / Q000188:drug therapy / Q000401:mortality / Q000473:pathology / Q000556:secondary / Q000601:surgery; D014059:Tongue / Q000473:pathology; D014062:Tongue Neoplasms / Q000175:diagnosis / Q000401:mortality / Q000473:pathology / Q000556:secondary*