title: Treatment of pediatric Ogilvie's syndrome with low-dose erythromycin: a case report.
abstract: Acute colonic pseudo-obstruction is a poorly understood syndrome, characterized by the signs, symptoms and radiological pattern of a large bowel obstruction without evidence for a mechanical obstruction. We report a case of a 2-year old boy who presented with progressive abdominal distention, vomiting and abdominal pain on postoperative d 3. Plain abdominal z-ray showed markedly dilated large bowel. Mechanical colonic obstruction was ruled out with hypaque enema. Ogilvie's syndrome was suspected. The patient received treatment with oral erythromycin which had an immediate beneficial effect. During the 6 mo follow-up, no recurrences of symptoms were observed. We provide a safe and effective therapy for Ogilvie's syndrome in pediatric individuals.
authors.affiliation: Department of Pediatric Surgery, Second Affiliated Hospital of Harbin Medical University, #246 Xuefu Road, Harbin 150086, Heilongjiang Province, China. jdp509@163.com
authors.forename: Da-Peng
authors.initials: DP
authors.lastname: Jiang
authors.forename: Zhao-Zhu
authors.initials: ZZ
authors.lastname: Li
authors.forename: Sheng-Yang
authors.initials: SY
authors.lastname: Guan
authors.forename: Yu-Bo
authors.initials: YB
authors.lastname: Zhang
mesh_terms: D002675:Child, Preschool; D003112:Colonic Pseudo-Obstruction / Q000175:diagnosis / Q000188:drug therapy*; D004305:Dose-Response Relationship, Drug; D004917:Erythromycin / Q000009:adverse effects / Q000627:therapeutic use*; D005765:Gastrointestinal Agents / Q000009:adverse effects / Q000627:therapeutic use*; D006801:Humans; D008297:Male
chemical_list: D005765:Gastrointestinal Agents; D004917:Erythromycin