title: Unusual variants of non-Langerhans cell histiocytoses.
abstract: Histiocytic syndromes represent a large, heterogeneous group of diseases resulting from proliferation of histiocytes. In addition to the classic variants, the subset of non-Langerhans cell histiocytoses comprises rare entities that have more recently been described. These last include both forms that affect only the skin or the skin and mucous membranes, and usually show a benign clinical behavior, and forms involving also internal organs, which may follow an aggressive course. The goal of this review is to outline the clinical, histologic, and ultrastructural features and the course, prognosis, and management of these unusual histiocytic syndromes.
authors.affiliation: Institute of Dermatological Sciences, University of Milan-Fondazione IRCCS Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, Milan, Italy.
authors.forename: Ruggero
authors.initials: R
authors.lastname: Caputo
authors.forename: Angelo Valerio
authors.initials: AV
authors.lastname: Marzano
authors.forename: Emanuela
authors.initials: E
authors.lastname: Passoni
authors.forename: Emilio
authors.initials: E
authors.lastname: Berti
mesh_terms: D000328:Adult; D002648:Child; D003937:Diagnosis, Differential; D015616:Histiocytosis, Non-Langerhans-Cell / Q000145:classification / Q000175:diagnosis / Q000473:pathology / Q000628:therapy; D006801:Humans