Emergency department management of the salicylate-poisoned patient.
Salicylate toxicity continues to be encountered commonly in emergency medicine. This article portrays the signs and symptoms of salicylate toxicity, reviews the erratic absorption and elimination kinetics, describes the devastating physiologic effects of overdose, and illustrates the potentially subtle manifestations of chronic aspirin toxicity.
O'Malley
Gerald F
GF
Division of Toxicology, Albert Einstein Medical Center, Philadelphia, PA 19141, USA. omalleyg@einstein.edu
D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000097:blood / Q000493:pharmacokinetics / Q000506:poisoning*; D001241:Aspirin / Q000097:blood / Q000493:pharmacokinetics / Q000506:poisoning; D062787:Drug Overdose / Q000175:diagnosis / Q000503:physiopathology; D004636:Emergency Service, Hospital; D006801:Humans; D006435:Renal Dialysis; D012151:Resuscitation / Q000379:methods*; D012459:Salicylates / Q000097:blood / Q000493:pharmacokinetics / Q000506:poisoning*
D000894:Anti-Inflammatory Agents, Non-Steroidal; D012459:Salicylates; D001241:Aspirin