Pulmonary sclerosing hemangioma detected by fluorodeoxyglucose positron emission tomography in familial adenomatous polyposis: report of a case.
We present a 53-year-old female suffering from familial adenomatous polyposis, who was found to have a positive nodus, lateral to the hilus of the left lung, on routine FDG-PET scan. This lesion was found to be a sclerosing hemangioma. We found an aberrant beta-catenin expression on immunohistochemical staining, suggesting that sclerosing hemangioma and familial adenomatous polyposis share the same pathophysiology. It is important to be aware of the association of familial adenomatous polyposis and sclerosing hemangioma.
de Koning
Daan B
DB
Department of Medicine, Division of Gastroenterology and Hepatology, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands.
Drenth
Joost P H
JP
Oyen
Wim J G
WJ
Wagenaar
Michiel
M
Aliredjo
Riena P
RP
Nagengast
Fokko M
FM
D011125:Adenomatous Polyposis Coli / Q000453:epidemiology* / Q000503:physiopathology; D015897:Comorbidity; D005260:Female; D019298:Glucose-6-Phosphate / Q000031:analogs & derivatives; D006801:Humans; D007150:Immunohistochemistry; D008875:Middle Aged; D049268:Positron-Emission Tomography; D047868:Pulmonary Sclerosing Hemangioma / Q000453:epidemiology* / Q000378:metabolism / Q000473:pathology / Q000503:physiopathology; D051176:beta Catenin / Q000378:metabolism
D051176:beta Catenin; C047515:2-fluoro-2-deoxyglucose-6-phosphate; D019298:Glucose-6-Phosphate