title: Metastatic melanoma to the kidney presenting with renal vein tumor thrombus.
abstract: We report on a patient with metastatic melanoma to the kidney who presented with a renal vein thrombus to the inferior vena cava. Three years after his initial lesion of the scalp, a 34-year-old Egyptian man was found to have two brain metastases and an 11-cm left renal metastasis with a tumor thrombus in the renal vein. After resection of the brain metastases, with no evidence of additional metastases, the patient underwent left radical nephrectomy and tumor venous thrombectomy. The patient later had tumor recurrence at multiple sites. He did not respond to systemic treatment and died 5 months later.
authors.affiliation: Department of Urology, University of California-Los Angeles, David Geffen School of Medicine, Los Angeles, California 90095-1738, USA.
authors.forename: Tobias
authors.initials: T
authors.lastname: Klatte
authors.forename: Jian Yu
authors.initials: JY
authors.lastname: Rao
authors.forename: Antoni
authors.initials: A
authors.lastname: Ribas
authors.forename: Allan J
authors.initials: AJ
authors.lastname: Pantuck
mesh_terms: D000328:Adult; D001707:Biopsy, Needle; D003937:Diagnosis, Differential; D018450:Disease Progression; D017809:Fatal Outcome; D006801:Humans; D007150:Immunohistochemistry; D007680:Kidney Neoplasms / Q000175:diagnosis / Q000556:secondary* / Q000601:surgery; D008297:Male; D008545:Melanoma / Q000473:pathology / Q000556:secondary* / Q000601:surgery; D009367:Neoplasm Staging; D009360:Neoplastic Cells, Circulating / Q000473:pathology*; D009392:Nephrectomy / Q000379:methods; D012082:Renal Veins; D012878:Skin Neoplasms / Q000473:pathology* / Q000601:surgery; D020246:Venous Thrombosis / Q000473:pathology*