Safety and efficacy of overnight orthokeratology in myopic children.
BACKGROUND
This prospective case series was conducted to describe the safety and efficacy of orthokeratology with the Emerald Contact Lens for Overnight Orthokeratology (Oprifocon A; Euclid Systems Corporation, Herndon, Virginia) among young myopes.


METHODS
Twenty subjects (ages 10 to 16) were enrolled in the 6-month pilot study. Subjects were fit empirically with overnight orthokeratology lenses and evaluated at 1 day, 1 week, 1 month, 2 months, 3 months, and 6 months.


RESULTS
Sixteen subjects completed the study. The mean baseline spherical equivalent refraction (SER) was -2.06 diopters (D) (+/-0.75). The mean SER at 6 months was -0.16 D (+/-0.38). The mean baseline uncorrected acuity was 0.78 (+/-0.28) logarithmic minimum angle of resolution (logMAR) equivalent (20/100 Snellen). The mean logMAR equivalent at 6 months was -0.03 +/- 0.12 (<20/20 Snellen). On average, 40% of eyes showed some type of corneal staining between the 1-week and 6-month visits. No serious adverse events occurred during the study.


CONCLUSIONS
In contrast to previously published studies that reported maximum results at 2 weeks, subjects reached maximum reduction in myopia at the 1-week visit and, on average, obtained a 92.2% reduction in spherical equivalent refractive error at 6 months. This pilot study lends to a growing body of evidence that short-term correction of mild to moderate myopia with overnight orthokeratology is safe and efficacious in children and adolescents.
Mika
Renée
R
Michigan College of Optometry, Ferris State University, Big Rapids, Michigan 49307, USA. mikar@ferris.edu <mikar@ferris.edu>
Morgan
Bruce
B
Cron
Michael
M
Lotoczky
Josh
J
Pole
John
J
D000293:Adolescent; D002648:Child; D002940:Circadian Rhythm; D003261:Contact Lenses / Q000009:adverse effects*; D003315:Cornea / Q000473:pathology; D006801:Humans; D009216:Myopia / Q000473:pathology / Q000628:therapy*; D010865:Pilot Projects; D013194:Staining and Labeling; D016896:Treatment Outcome