title: Fluid force predictions and experimental measurements for a magnetically levitated pediatric ventricular assist device.
abstract: The latest generation of artificial blood pumps incorporates the use of magnetic bearings to levitate the rotating component of the pump, the impeller. A magnetic suspension prevents the rotating impeller from contacting the internal surfaces of the pump and reduces regions of stagnant and high shear flow that surround fluid or mechanical bearings. Applying this third-generation technology, the Virginia Artificial Heart Institute has developed a ventricular assist device (VAD) to support infants and children. In consideration of the suspension design, the axial and radial fluid forces exerted on the rotor of the pediatric VAD were estimated using computational fluid dynamics (CFD) such that fluid perturbations would be counterbalanced. In addition, a prototype was built for experimental measurements of the axial fluid forces and estimations of the radial fluid forces during operation using a blood analog mixture. The axial fluid forces for a centered impeller position were found to range from 0.5 +/- 0.01 to 1 +/- 0.02 N in magnitude for 0.5 +/- 0.095 to 3.5 +/- 0.164 Lpm over rotational speeds of 6110 +/- 0.39 to 8030 +/- 0.57% rpm. The CFD predictions for the axial forces deviated from the experimental data by approximately 8.5% with a maximum difference of 18% at higher flow rates. Similarly for the off-centered impeller conditions, the maximum radial fluid force along the y-axis was found to be -0.57 +/- 0.17 N. The maximum cross-coupling force in the x direction was found to be larger with a maximum value of 0.74 +/- 0.22 N. This resulted in a 25-35% overestimate of the radial fluid force as compared to the CFD predictions; this overestimation will lead to a far more robust magnetic suspension design. The axial and radial forces estimated from the computational results are well within a range over which a compact magnetic suspension can compensate for flow perturbations. This study also serves as an effective and novel design methodology for blood pump developers employing magnetic suspensions. Following a final design evaluation, a magnetically suspended pediatric VAD will be constructed for extensive hydraulic and animal testing as well as additional validation of this design methodology.
authors.affiliation: Biomedical Engineering Department, Virginia Artificial Heart Institute, University of Virginia, Charlottesville, VA 22908, USA. alt2c@virginia.edu
authors.forename: Amy L
authors.initials: AL
authors.lastname: Throckmorton
authors.forename: Alexandrina
authors.initials: A
authors.lastname: Untaroiu
authors.forename: D Scott
authors.initials: DS
authors.lastname: Lim
authors.forename: Houston G
authors.initials: HG
authors.lastname: Wood
authors.forename: Paul E
authors.initials: PE
authors.lastname: Allaire
mesh_terms: D002648:Child; D004867:Equipment Design / Q000295:instrumentation*; D005544:Forecasting; D006353:Heart-Assist Devices; D018056:Hemorheology; D006801:Humans; D008280:Magnetics / Q000295:instrumentation*; D019563:Mechanics