title: [EVADEF registry, main data].
abstract: The EVADEF registry enrolled 2296 patients implanted with a defibrillator between june 2001 and june 2003 and followed up 24 months. Their main characteristics were the following: their mean age was 60+/-15S years, they were male in 86 %. Their left ventricular ejection fraction was 38.9 +/- 15.9 %. They were in NYHA class I or II for 83.8% of them, in class Ill for 14.7% and in class IV for only 1.5%. Secondary prevention indications concerned 82.1%, primary prevention 18.3%. Underlying cardiopathies were coronary artery disease in 61.3%, dilated cardiomyopathies in 15.9%. In a group of 7.1% there was no underlying heart disease. The implanted devices were VVI in 48.3%, DDD in 42.9%, biventricular pacemaker with defibrillator in 8.3% and dual defibrillator in 0.5%. Periprocedure complications concerned 13.8%. The most frequently reported was the presence of an haematoma. Periprocedure mortality concerned 8 patients, i.e. 0.3% of the total cohort. Mortality was 7.2% at 1 year and 11.3% at 2 years. Among the 274 deaths, a majority was due to heart failure (42%), arrhythmic storms represented only 6.2% of deaths. Hopefully it is likely that in the future association of cardiac resynchronization therapy to defibrillator will be able to decrease this death rate due to heart failure.
mesh_terms: D000368:Aged; D001145:Arrhythmias, Cardiac / Q000401:mortality / Q000628:therapy*; D002311:Cardiomyopathy, Dilated / Q000453:epidemiology; D003324:Coronary Artery Disease / Q000453:epidemiology; D017147:Defibrillators, Implantable / Q000009:adverse effects / Q000706:statistics & numerical data*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012042:Registries / Q000706:statistics & numerical data*; D016277:Ventricular Function, Left