A dinuclear Ni(mu-H)Ru complex derived from H2.
Models of the active site in [NiFe]hydrogenase enzymes have proven challenging to prepare. We isolated a paramagnetic dinuclear nickel-ruthenium complex with a bridging hydrido ligand from the heterolytic cleavage of H2 by a dinuclear NiRu aqua complex in water under ambient conditions (20 degrees C and 1 atmosphere pressure). The structure of the hexacoordinate Ni(mu-H)Ru complex was unequivocally determined by neutron diffraction analysis, and it comes closest to an effective analog for the core structure of the proposed active form of the enzyme.
Ogo
Seiji
S
Center for Future Chemistry, Kyushu University, Fukuoka 819-0395, Japan. ogo-tcm@mbox.nc.kyushu-u.ac.jp
Kabe
Ryota
R
Uehara
Keiji
K
Kure
Bunsho
B
Nishimura
Takashi
T
Menon
Saija C
SC
Harada
Ryosuke
R
Fukuzumi
Shunichi
S
Higuchi
Yoshiki
Y
Ohhara
Takashi
T
Tamada
Taro
T
Kuroki
Ryota
R
D001665:Binding Sites; D032701:Biomimetics; D002384:Catalysis; D003460:Crystallization; D018360:Crystallography, X-Ray; D006859:Hydrogen / Q000737:chemistry*; D006864:Hydrogenase / Q000737:chemistry* / Q000378:metabolism; D007501:Iron / Q000737:chemistry*; D008024:Ligands; D009682:Magnetic Resonance Spectroscopy; D018716:Molecular Mimicry; D033363:Neutron Diffraction; D009532:Nickel / Q000737:chemistry*; D009942:Organometallic Compounds / Q000138:chemical synthesis / Q000737:chemistry*; D012428:Ruthenium / Q000737:chemistry*; D021241:Spectrometry, Mass, Electrospray Ionization; D013055:Spectrophotometry, Infrared
C519603:(NiIIL)(H2O)(H)RuII(6-C6Me6))(NO3)((2)(NO3); D008024:Ligands; D009942:Organometallic Compounds; D009532:Nickel; D012428:Ruthenium; D006859:Hydrogen; D007501:Iron; D006864:Hydrogenase