[Psychopathology in female carriers of the fragile X mutation].
Fragile X syndrome is, after Down's syndrome, the most common form of mental retardation. Women are potential carriers and can have the defective gene on one of their two X chromosomes without developing the complete syndrome. In this paper we examine which psychiatric disturbances may appear or develop in women because they are carriers of the fragile X mutation. Carriers have been found to have a higher frequency of anxiety disorders, affective disorders and schizotypal features.
Hageman
S
S
Universitair Ziekenhuis Antwerpen, Belgium. hageman.s@belgacom.net
Van Den Eede
F
F
Vandendriessche
F
F
Claes
S
S
D000341:Affective Disorders, Psychotic / Q000453:epidemiology* / Q000235:genetics; D001008:Anxiety Disorders / Q000453:epidemiology* / Q000235:genetics; D005260:Female; D051860:Fragile X Messenger Ribonucleoprotein 1 / Q000235:genetics*; D005600:Fragile X Syndrome / Q000150:complications / Q000235:genetics* / Q000523:psychology; D006579:Heterozygote; D006801:Humans; D008297:Male; D009154:Mutation; D012569:Schizotypal Personality Disorder / Q000453:epidemiology* / Q000235:genetics
D051860:Fragile X Messenger Ribonucleoprotein 1