title: Efficacy and tolerability of liposomal heparin spraygel as an add-on treatment in the management of superficial venous thrombosis.
abstract: Superficial venous thrombosis usually resolves spontaneously in a few weeks. In most cases, treatment includes peroral analgesics or nonsteroidal anti-inflammatory drugs accompanied by the recommendation to wear elastic stockings and perform regular mild ambulation. In contrast to this "standard treatment," a recent ACCP guideline has recommended that patients affected by spontaneous superficial thrombophlebitis be treated with intermediate doses of unfractionated or low-molecular-weight heparin. This study was designed to assess the efficacy of topically applied heparin spraygel in terms of reduction of local symptoms and signs of superficial venous thrombosis.
authors.affiliation: Department of Angiology, Hanuschkrankenhaus, Vienna, Austria. Reinhold.katzenschlager@wgkk.sozvers.at
authors.forename: Reinhold
authors.initials: R
authors.lastname: Katzenschlager
authors.forename: Ara
authors.initials: A
authors.lastname: Ugurlouglu
authors.forename: Gyula
authors.initials: G
authors.lastname: Sipos
authors.forename: Imre
authors.initials: I
authors.lastname: Bihari
authors.forename: Eva B
authors.initials: EB
authors.lastname: Anyova
authors.forename: Mirko
authors.initials: M
authors.lastname: Hirschl
authors.forename: Marek
authors.initials: M
authors.lastname: Maruszynski
authors.forename: Wojciech
authors.initials: W
authors.lastname: Noszczyk
authors.forename: Zbigniew
authors.initials: Z
authors.lastname: Rybak
authors.forename: Andrzej
authors.initials: A
authors.lastname: Cencora
mesh_terms: D000287:Administration, Topical; D000328:Adult; D000925:Anticoagulants / Q000008:administration & dosage* / Q000009:adverse effects; D005260:Female; D005782:Gels; D006493:Heparin / Q000008:administration & dosage* / Q000009:adverse effects; D006801:Humans; D008081:Liposomes; D008297:Male; D008875:Middle Aged; D016896:Treatment Outcome; D020246:Venous Thrombosis / Q000188:drug therapy*
chemical_list: D000925:Anticoagulants; D005782:Gels; D008081:Liposomes; D006493:Heparin