title: Alkaloids from Galanthus nivalis.
abstract: Phytochemical studies on Galanthus nivalis of Bulgarian origin resulted in the isolation of five compounds: 11-O-(3'-hydroxybutanoyl)hamayne, 3,11-O-(3',3''-dihydroxybutanoyl)hamayne, 3-O-(2''-butenoyl)-11-O-(3'-hydroxybutanoyl)hamayne, 3,11,3''-O-(3',3'',3'''-trihydroxybutanoyl)hamayne, and 2-O-(3'-acetoxybutanoyl)lycorine, together with five known alkaloids: ungeremine, lycorine, tazettine, hamayne, and ismine. Their structures were determined by (1)H and (13)C NMR spectroscopy and two-dimensional (1)H-(1)H and (1)H-(13)C chemical shift correlation experiments.
authors.affiliation: Departament de Productes Naturals, Biologia Vegetal i Edafologia, Facultat de Farmàcia, Universitat de Barcelona, Av. Joan XXIII s/n, 08028 Barcelona, Spain.
authors.forename: Strahil
authors.initials: S
authors.lastname: Berkov
authors.forename: Carles
authors.initials: C
authors.lastname: Codina
authors.forename: Francesc
authors.initials: F
authors.lastname: Viladomat
authors.forename: Jaume
authors.initials: J
authors.lastname: Bastida
mesh_terms: D000470:Alkaloids / Q000737:chemistry* / Q000302:isolation & purification; D027801:Galanthus / Q000737:chemistry*; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular
chemical_list: D000470:Alkaloids