title: Aphasia: associated disturbances in affect, behavior, and cognition in the setting of speech and language difficulties.
abstract: Patients with disturbances in affect, behavior, and cognition present a variety of challenges to healthcare providers; their evaluation and treatment becomes especially problematic in the setting of speech and language difficulties. The authors present the case of a man who sustained a left-side cerebrovascular accident with aphasia and discuss the approach to his diagnosis and treatment. Moreover, since a variety of speech and language problems can arise after stroke and since patients and their treaters can become frustrated by impaired communication and diagnostic uncertainties, authors review the clinical manifestations, timing, and treatment of such conditions so that treatment can be improved.
authors.affiliation: Dept. of Neurology and Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA. SBullain@Partners.org
authors.forename: Szofia S
authors.initials: SS
authors.lastname: Bullain
authors.forename: Lyvia S
authors.initials: LS
authors.lastname: Chriki
authors.forename: Theodore A
authors.initials: TA
authors.lastname: Stern
mesh_terms: D000928:Antidepressive Agents / Q000008:administration & dosage; D001037:Aphasia / Q000209:etiology / Q000523:psychology*; D001794:Blood Pressure; D001921:Brain / Q000000981:diagnostic imaging; D003072:Cognition Disorders / Q000209:etiology / Q000523:psychology*; D003865:Major Depressive Disorder / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy; D005343:Fibrinolytic Agents / Q000008:administration & dosage; D006339:Heart Rate; D006801:Humans; D007806:Language Disorders / Q000209:etiology / Q000523:psychology*; D008297:Male; D001523:Mental Disorders / Q000209:etiology / Q000523:psychology*; D008875:Middle Aged; D019964:Mood Disorders / Q000209:etiology / Q000523:psychology*; D017367:Selective Serotonin Reuptake Inhibitors / Q000008:administration & dosage; D013064:Speech Disorders / Q000209:etiology / Q000523:psychology*; D020521:Stroke / Q000150:complications / Q000175:diagnosis / Q000523:psychology; D010959:Tissue Plasminogen Activator / Q000008:administration & dosage; D014057:Tomography, X-Ray Computed / Q000379:methods
chemical_list: D000928:Antidepressive Agents; D005343:Fibrinolytic Agents; D017367:Selective Serotonin Reuptake Inhibitors; D010959:Tissue Plasminogen Activator