title: Daytime, home and office blood pressures in treated hypertensive patients according to accretion of cardiovascular risk.
abstract: The relative accuracy of office, home and ambulatory blood pressure (BP) measurements has not been established in patients with metabolic syndrome (MS+). We set out to compare BP values obtained using different measurement modalities and their relationship to MS intensity in hypertensive outpatients. Office, ambulatory and home BPs and risk profile were ascertained. MS was defined according to ATPIII criteria. The study included a cohort of 104 men and 132 women with a mean age of 51.8 +/- 14.2 years; 40.3% had metabolic syndrome (MS+). The MS+ patients had higher home SBP (150 vs 142 mmHg, p < 0.01), were treated with more drugs (3.9 vs 3.0, p < 0.001) and had a poorer BP control on home measurements (11.6 vs 24.8%, p = 0.01). However, the clinical BP control rates were overall higher, and did not differ between two groups when daytime ambulatory (34.7 vs 27%) or office (26.7 vs 22.3%) values were employed. The deviation of home measurements was associated in a dose-dependent fashion with intensity of MS. Thus, in MS+ patients, the well standardized measurement protocols and equipment should be used to assess the antihypertensive efficacy. This is especially true for patients with high body mass index.
authors.affiliation: Hypertension Unit, Department of Hypertension and Diabetes, Medical University of Gdańsk, Poland. jerzy.gasowski@wp.pl
authors.forename: Jerzy
authors.initials: J
authors.lastname: Gasowski
authors.forename: Anna
authors.initials: A
authors.lastname: Szyndler
authors.forename: Angelina
authors.initials: A
authors.lastname: Dubiela
authors.forename: Katarzyna
authors.initials: K
authors.lastname: Smiałek
authors.forename: Marzena
authors.initials: M
authors.lastname: Chrostowska
authors.forename: Radosław
authors.initials: R
authors.lastname: Szczech
authors.forename: Leszek
authors.initials: L
authors.lastname: Bieniaszewski
authors.forename: Tomasz
authors.initials: T
authors.lastname: Grodzicki
authors.forename: Krzysztof
authors.initials: K
authors.lastname: Narkiewicz
mesh_terms: D000328:Adult; D000368:Aged; D000886:Anthropometry; D000959:Antihypertensive Agents / Q000627:therapeutic use; D001786:Blood Glucose / Q000032:analysis; D018660:Blood Pressure Monitoring, Ambulatory; D002318:Cardiovascular Diseases / Q000453:epidemiology*; D002784:Cholesterol / Q000097:blood; D008076:Cholesterol, HDL / Q000097:blood; D008078:Cholesterol, LDL / Q000097:blood; D002940:Circadian Rhythm; D004777:Environment; D005260:Female; D006801:Humans; D006949:Hyperlipidemias / Q000453:epidemiology; D006973:Hypertension / Q000188:drug therapy / Q000453:epidemiology / Q000503:physiopathology* / Q000523:psychology; D008297:Male; D024821:Metabolic Syndrome / Q000453:epidemiology / Q000503:physiopathology*; D008875:Middle Aged; D011044:Poland / Q000453:epidemiology; D011237:Predictive Value of Tests; D012111:Residence Characteristics; D012307:Risk Factors; D012907:Smoking / Q000453:epidemiology; D014280:Triglycerides / Q000097:blood; D017132:Workplace
chemical_list: D000959:Antihypertensive Agents; D001786:Blood Glucose; D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D014280:Triglycerides; D002784:Cholesterol