title: Signal changes of superior cerebellar peduncle on fluid-attenuated inversion recovery in progressive supranuclear palsy.
abstract: Pathological changes of the superior cerebellar peduncle (SCP) can occur in PSP. We assessed the clinical history and signal changes in the SCP on fluid-attenuated inversion recovery (FLAIR) images of 12 patients with clinically probable PSP. Three control groups were studied: Parkinson's disease (PD), multiple system atrophy with predominant parkinsonian features (MSA-P), and healthy controls. Three patients who had clinically probable PSP showed increased FLAIR signals within the SCP. No subject with PD or MSA-P showed any signal changes of the SCP. The signal changes in the SCP on FLAIR may be one indicator for differentiating PSP from other parkinsonian diseases.
authors.affiliation: Department of Neurology, Nara Medical University, 840 Shijo-cho, Kashihara, Nara 634-8522, Japan. hk55@naramed-u.ac.jp
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Kataoka
authors.forename: Yasuyo
authors.initials: Y
authors.lastname: Tonomura
authors.forename: Toshiaki
authors.initials: T
authors.lastname: Taoka
authors.forename: Satoshi
authors.initials: S
authors.lastname: Ueno
mesh_terms: D000368:Aged; D002531:Cerebellum / Q000473:pathology*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D013494:Supranuclear Palsy, Progressive / Q000473:pathology*