Rapid synthesis of the A-E fragment of ciguatoxin CTX3C.
The A-E fragment of the marine natural product CTX3C has been prepared in an efficient manner by using a strategy in which two-directional and iterative ring-closing metathesis (RCM) reactions were employed for ring construction.
Clark
J Stephen
JS
WestCHEM, Department of Chemistry, Joseph Black Building, University of Glasgow, University Avenue, Glasgow G12 8QQ, UK. stephenc@chem.gla.ac.uk
Conroy
Joanne
J
Blake
Alexander J
AJ
D000818:Animals; D001688:Biological Products / Q000737:chemistry; D002922:Ciguatoxins / Q000138:chemical synthesis* / Q000737:chemistry* / Q000378:metabolism; D004141:Dinoflagellida / Q000737:chemistry; D015394:Molecular Structure
D001688:Biological Products; D002922:Ciguatoxins