title: Antibacterial activity of ciprofloxacin against clinical strains of Vibrio cholerae O139 recently isolated from India.
abstract: We determined the in vitro antibacterial activity of ciprofloxacin against Vibrio cholerae O139 recently isolated from cholera patients in India. Ciprofloxacin showed excellent antibacterial activity against the O139 strains, and ciprofloxacin-resistant O139 strains were not observed. The lack of incidence of ciprofloxacin resistance in O139 strains may be because O139 strains appeared comparatively recently and have not been extensively treated with antibacterial agents including fluoroquinolones.
authors.affiliation: New Product Research Laboratories I, Daiichi Pharmaceutical Co. Ltd., Tokyo, Japan. okudaj@hiroshima-u.ac.jp
authors.forename: Jun
authors.initials: J
authors.lastname: Okuda
authors.forename: Thandavarayan
authors.initials: T
authors.lastname: Ramamurthy
authors.forename: Shinji
authors.initials: S
authors.lastname: Yamasaki
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology* / Q000627:therapeutic use; D002771:Cholera / Q000188:drug therapy / Q000382:microbiology*; D002939:Ciprofloxacin / Q000494:pharmacology* / Q000627:therapeutic use; D024881:Drug Resistance, Bacterial; D006801:Humans; D007194:India; D041242:Vibrio cholerae O139 / Q000187:drug effects* / Q000302:isolation & purification
chemical_list: D000900:Anti-Bacterial Agents; D002939:Ciprofloxacin