Ca2+ channel alpha2-delta ligands for the treatment of neuropathic pain.
Field
Mark J
MJ
Pfizer Global Research and Development, Sandwich Laboratories, Sandwich, Kent CT13 9NJ, UK.
Li
Zheng
Z
Schwarz
Jacob B
JB
D000588:Amines / Q000737:chemistry / Q000494:pharmacology / Q000627:therapeutic use; D000700:Analgesics / Q000737:chemistry / Q000494:pharmacology* / Q000627:therapeutic use; D000818:Animals; D000927:Anticonvulsants / Q000737:chemistry / Q000494:pharmacology / Q000627:therapeutic use; D015220:Calcium Channels / Q000235:genetics / Q000378:metabolism / Q000502:physiology*; D002264:Carboxylic Acids / Q000737:chemistry / Q000494:pharmacology / Q000627:therapeutic use; D003509:Cyclohexanecarboxylic Acids / Q000737:chemistry / Q000494:pharmacology / Q000627:therapeutic use; D000077206:Gabapentin; D006801:Humans; D008024:Ligands; D051379:Mice; D008817:Mice, Mutant Strains; D010146:Pain / Q000188:drug therapy* / Q000378:metabolism; D010523:Peripheral Nervous System Diseases / Q000188:drug therapy* / Q000378:metabolism / Q000503:physiopathology; D000069583:Pregabalin; D011355:Prodrugs / Q000737:chemistry / Q000494:pharmacology / Q000627:therapeutic use; D005680:gamma-Aminobutyric Acid / Q000031:analogs & derivatives / Q000737:chemistry / Q000494:pharmacology / Q000627:therapeutic use
D000588:Amines; D000700:Analgesics; D000927:Anticonvulsants; D015220:Calcium Channels; D002264:Carboxylic Acids; D003509:Cyclohexanecarboxylic Acids; D008024:Ligands; D011355:Prodrugs; C494035:voltage gated calcium channel subunit Ca alpha2delta-1, human; D000069583:Pregabalin; D005680:gamma-Aminobutyric Acid; D000077206:Gabapentin