title: Sulfur-containing spiroketal glycosides from Breynia fruticosa.
abstract: Phytochemical investigation of the chemical constituents of the aerial parts of Breynia fruticosa afforded 10 sulfur-containing spiroketal glycosides, including eight new compounds (1-8) and two known compounds, epibreynin B (9) and breynin B (10). Epibreynin B (9) was previously reported as a semisynthetic oxidation product of breynin A and is now reported from a natural source for the first time. The structures of 1-10 were determined on the basis of spectroscopic and chemical methods.
authors.affiliation: Shanghai Institute of Materia Medica, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 201203, People's Republic of China.
authors.forename: Dahai
authors.initials: D
authors.lastname: Meng
authors.forename: Wenliang
authors.initials: W
authors.lastname: Chen
authors.forename: Weimin
authors.initials: W
authors.lastname: Zhao
mesh_terms: D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D019665:Euphorbiaceae / Q000737:chemistry*; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D015394:Molecular Structure; D010946:Plants, Medicinal / Q000737:chemistry*; D013141:Spiro Compounds / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D013457:Sulfur Compounds / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
chemical_list: D004365:Drugs, Chinese Herbal; D006027:Glycosides; D013141:Spiro Compounds; D013457:Sulfur Compounds