[Short and mid-term effects of percutaneous transcatheter closure of ventricular septal defects on the cardiac remodeling].
OBJECTIVE
To evaluate the short and mid-term changes of the cardiac morphology after percutaneous transcatheter closure of ventricular septal defects (VSD) with transthoracic echocardiography (TTE).


METHODS
The left ventricular end-diastolic diameter (LVEDD), left ventricular end-diastolic volume (LVEDV), left atrial diameter (LAd), and right ventricular diameter (RVd) in 30 VSD patients were measured before the VSD closure,and on the 3rd day, 3rd month, and 6th month after the VSD closure by TTE.


RESULTS
LVEDD and LVEDV significantly decreased on the 3rd day after the VSD closure compared with pre-VSD closure. LVEDD and LVEDV continuously decreased on the 3rd month and 6th month after the VSD closure. LAd was smaller on the 3rd month and 6th month after the VSD closure, but there was not significant difference between the 3rd and 6th month. RVd increased on the 3rd day after the VSD closure, while no significant difference was found among the 3rd month and 6th month before and after VSD closure.


CONCLUSIONS
Percutaneous transcatheter VSD closure may effectively improve the cardiac remodeling in VSD patients in the short and mid-term follow-up.
Zheng
Zhao-Fen
ZF
Department of Cardiology, Xiangya Hospital, Central South University, Changsha, China. xyxnzzf@126.com
Pu
Xiao-Qun
XQ
Yang
Tian-Lun
TL
Chen
Xiao-Bin
XB
Li
Chuan-Chang
CC
Mo
Long
L
Zhang
Li-Hui
LH
Xie
Wei
W
Deng
Jin-Hua
JH
D000293:Adolescent; D000328:Adult; D006328:Cardiac Catheterization / Q000379:methods*; D002648:Child; D002675:Child, Preschool; D004452:Echocardiography; D005260:Female; D005500:Follow-Up Studies; D006345:Heart Septal Defects, Ventricular / Q000000981:diagnostic imaging / Q000628:therapy*; D006801:Humans; D008297:Male; D019919:Prosthesis Implantation / Q000379:methods*; D013997:Time Factors; D020257:Ventricular Remodeling