Gynura root induces hepatic veno-occlusive disease: a case report and review of the literature.
Gynura root has been used extensively in Chinese folk medicine and plays a role in promoting microcirculation and relieving pain. However, its hepatic toxicity should not be neglected. Recently, we admitted a 62-year old female who developed hepatic veno-occlusive disease (HVOD) after ingestion of Gynura root. Only a few articles on HVOD induced by Gynura root have been reported in the literature. It is suspected that pyrrolizidine alkaloids in Gynura root might be responsible for HVOD. In this paper, we report a case of HVOD and review the literature.
Dai
Ning
N
Department of Hepato-gastroenterology, Sir Run Run Shaw Affiliated Hospital of Medical College of Zhejiang University, Hangzhou 310016, Zhejiang Province, China. ndaicn@yahoo.com
Yu
Ying-Cong
YC
Ren
Tian-Hua
TH
Wu
Jia-Guo
JG
Jiang
Yuan
Y
Shen
Lai-Gen
LG
Zhang
Jing
J
D019659:Asteraceae / Q000009:adverse effects*; D004365:Drugs, Chinese Herbal / Q000009:adverse effects* / Q000627:therapeutic use; D005260:Female; D006504:Hepatic Veno-Occlusive Disease / Q000175:diagnosis / Q000209:etiology*; D006801:Humans; D008875:Middle Aged; D019547:Neck Pain / Q000188:drug therapy; D008517:Phytotherapy / Q000009:adverse effects*; D018517:Plant Roots / Q000009:adverse effects*
D004365:Drugs, Chinese Herbal