title: Alcohol intake and breast cancer risk among young women.
abstract: BACKGROUND
  Alcohol intake has been consistently associated with breast cancer risk, but the importance of timing of intake and the impact of beverage type are unclear.
  
  
  METHODS
  We evaluated whether early, lifetime or recent alcohol intake was associated with breast cancer risk, and whether risk varied by type of alcoholic drinks in 1,728 newly diagnosed population-based breast cancer patients and 435 control subjects aged 20-49 years. We used multivariable logistic regression models to estimate odds ratios (OR) and 95% confidence intervals (CI) as measures of the relative risk of breast cancer associated with intake of alcoholic drinks.
  
  
  RESULTS
  Intake of alcoholic drinks during the recent five year period before the breast cancer diagnosis was associated with increased breast cancer risk (P (trend) = 0.04). Intake of two or more alcoholic drinks per day during this five year period was associated with an 82% increase in breast cancer risk relative to never drinkers (OR = 1.82, 95% CI = 1.01-3.28). No risk increase was observed for alcohol intake at ages 15-20 years or for lifetime alcohol intake. Risk did not vary by type of alcohol consumed.
  
  
  CONCLUSIONS
  Our results suggest that recent alcohol consumption may be associated with increased breast cancer risk in young women.
authors.affiliation: Institute of Basic Medical Sciences, Department of Nutrition, University of Oslo, Oslo, Norway.
authors.forename: Paula
authors.initials: P
authors.lastname: Berstad
authors.forename: Huiyan
authors.initials: H
authors.lastname: Ma
authors.forename: Leslie
authors.initials: L
authors.lastname: Bernstein
authors.forename: Giske
authors.initials: G
authors.lastname: Ursin
mesh_terms: D000293:Adolescent; D000328:Adult; D000428:Alcohol Drinking / Q000009:adverse effects*; D001515:Beer / Q000009:adverse effects; D001943:Breast Neoplasms / Q000139:chemically induced*; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D008875:Middle Aged; D012307:Risk Factors; D014920:Wine / Q000009:adverse effects