Progressive ORF virus infection in a patient with lymphoma: successful treatment using imiquimod.
Orf virus is a parapoxvirus that infects small ruminants worldwide. We present the case report of a 73-year-old woman with non-Hodgkins lymphoma who developed progressive orf virus lesions that were unresponsive to surgical debridement and to cidofovir therapy. The patient's orf virus infection was successfully treated with topical imiquimod despite progression of her malignancy.
Lederman
Edith R
ER
Division of Viral and Rickettsial Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA. dvk9@cdc.gov
Green
Gary M
GM
DeGroot
Henry E
HE
Dahl
Patricia
P
Goldman
Erinn
E
Greer
Patricia W
PW
Li
Yu
Y
Zhao
Hui
H
Paddock
Christopher D
CD
Damon
Inger K
IK
D000276:Adjuvants, Immunologic / Q000627:therapeutic use*; D000368:Aged; D000634:Aminoquinolines / Q000627:therapeutic use*; D004474:Ecthyma, Contagious / Q000150:complications / Q000188:drug therapy* / Q000473:pathology; D005260:Female; D006801:Humans; D000077271:Imiquimod; D008228:Lymphoma, Non-Hodgkin / Q000150:complications*
D000276:Adjuvants, Immunologic; D000634:Aminoquinolines; D000077271:Imiquimod