title: (S)-3-(Ammoniomethyl)-5-methylhexanoate (pregabalin).
abstract: The title compound, C(8)H(17)NO(2), exists as a zwitterion, adopting a propeller conformation. Molecules self-assemble to form a hydrogen-bonded layer parallel to the ab crystallographic plane connected by N+-H...O- and C-H...O- hydrogen bonds. These layers are stacked along the c axis and are stabilized by van der Waals interactions.
authors.affiliation: Centre for Excellence in Polymorphism, Dr Reddy's Laboratories Ltd, Bollaram, Hyderabad, India.
authors.forename: Nalivela
authors.initials: N
authors.lastname: Venu
authors.forename: Peddy
authors.initials: P
authors.lastname: Vishweshwar
authors.forename: Thaimattam
authors.initials: T
authors.lastname: Ram
authors.forename: Devarakonda
authors.initials: D
authors.lastname: Surya
authors.forename: Bhattacharya
authors.initials: B
authors.lastname: Apurba
mesh_terms: D000700:Analgesics / Q000737:chemistry; D014151:Anti-Anxiety Agents / Q000737:chemistry; D018360:Crystallography, X-Ray; D006860:Hydrogen Bonding; D008958:Models, Molecular; D008968:Molecular Conformation; D015394:Molecular Structure; D000069583:Pregabalin; D005680:gamma-Aminobutyric Acid / Q000031:analogs & derivatives* / Q000737:chemistry
chemical_list: D000700:Analgesics; D014151:Anti-Anxiety Agents; D000069583:Pregabalin; D005680:gamma-Aminobutyric Acid