title: Severe serotonin toxicity and manic switch induced by combined use of tramadol and paroxetine.
authors.forename: Alexander Panickacheril
authors.initials: AP
authors.lastname: John
authors.forename: Radhakrishan
authors.initials: R
authors.lastname: Koloth
mesh_terms: D000701:Analgesics, Opioid / Q000008:administration & dosage / Q000009:adverse effects*; D001714:Bipolar Disorder / Q000188:drug therapy* / Q000523:psychology*; D003865:Major Depressive Disorder / Q000150:complications / Q000188:drug therapy; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D008875:Middle Aged; D010146:Pain / Q000150:complications; D017374:Paroxetine / Q000008:administration & dosage / Q000009:adverse effects*; D020230:Serotonin Syndrome / Q000139:chemically induced*; D017367:Selective Serotonin Reuptake Inhibitors / Q000008:administration & dosage / Q000009:adverse effects*; D014147:Tramadol / Q000008:administration & dosage / Q000009:adverse effects*
chemical_list: D000701:Analgesics, Opioid; D017374:Paroxetine; D017367:Selective Serotonin Reuptake Inhibitors; D014147:Tramadol