title: [Primary cardiac sarcoma. Description of a case].
abstract: Primary cardiac tumors are rare events. We describe here a case of undifferentiated pleomorphic sarcoma (so-called pleomorphic malignant fibrous histiocytoma) obliterating mostly the left side and the anterior wall of pericardium in a 84-year-old man admitted for mild dyspnea at rest. The diagnosis was suspected after excluding the lung origin of the mass (observed by plain chest radiography) by thorax computed tomography but it was confirmed only by cardiac-gated magnetic resonance imaging and transthoracic biopsy. Considering both patient's age and comorbidity, and local extension of the lesion, after counseling with cardiac surgeons and oncologists, the patient was treated only by conservative medical therapy. The patient died 6 months after the diagnosis due to a superior vena cava syndrome as an effect of infiltration and obstruction of superior vena cava by the tumor at the site of vein entry in the right atrium. This case is an example of a primary cardiac tumor that causes relative myocardial sufferance both by infiltration and by limitation of normal heart diastolic function.
authors.affiliation: Divisione di Medicina Interna II, Dipartimento di Medicine e Specialità Mediche, Università degli Studi di Modena e Reggio Emilia, Modena.
authors.forename: Silvia
authors.initials: S
authors.lastname: Tremosini
authors.forename: Alberto
authors.initials: A
authors.lastname: Vegetti
authors.forename: Dimitriy
authors.initials: D
authors.lastname: Arioli
authors.forename: Paolo
authors.initials: P
authors.lastname: Ventura
authors.forename: Giulio
authors.initials: G
authors.lastname: Rossi
authors.forename: Maria Grazia
authors.initials: MG
authors.lastname: Modena
authors.forename: Maria Luisa
authors.initials: ML
authors.lastname: Zeneroli
mesh_terms: D000230:Adenocarcinoma; D000369:Aged, 80 and over; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000627:therapeutic use; D001706:Biopsy; D001803:Blood Transfusion; D004232:Diuretics / Q000627:therapeutic use; D004417:Dyspnea / Q000209:etiology; D017809:Fatal Outcome; D006338:Heart Neoplasms / Q000150:complications / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy; D051677:Histiocytoma, Malignant Fibrous / Q000150:complications / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D009378:Neoplasms, Multiple Primary; D010166:Palliative Care; D011471:Prostatic Neoplasms; D013479:Superior Vena Cava Syndrome / Q000209:etiology; D014057:Tomography, X-Ray Computed
chemical_list: D000806:Angiotensin-Converting Enzyme Inhibitors; D004232:Diuretics