title: Retroperitoneal ganglioneuroma with lymphnode metastasis: a case report.
abstract: Ganglioneuroma is a benign, most differentiated tumor of neural crest origin. These tumors though benign, can very rarely metastasize to regional lymphnodes or to distant sites. We report a case of a 52 year old lady who presented to the surgical OPD with dyspeptic symptoms of 2 months duration. Ultrasonography and CT scan of the abdomen showed a homogenous mass in the region of the right adrenal gland, extending between the inferior vena cava and the aorta. A clinical and radiological diagnosis of an adrenal tumor was made. Microscopically, the tumor histology was that of a ganglioneuroma (schwannian stroma-dominant) mature type. The lymph node attached to the tumor showed metastasis, the metastatic foci having the same morphology as the primary tumor. The right adrenal gland was free of tumor. The case is illustrative due to its clinical presentation mimicking an adrenal incidentaloma, and a rare phenomenon of a benign tumor exhibiting completely differentiated lymph node metastasis.
authors.affiliation: Department of Pathology, Kasturba Medical College, Manipal, Karnataka. srirang72@yahoo.com
authors.forename: R
authors.initials: R
authors.lastname: Srinivasan
authors.forename: K Sreedharan V
authors.initials: KS
authors.lastname: Koliyadan
authors.forename: Geetha
authors.initials: G
authors.lastname: Krishnand
authors.forename: Sudha S
authors.initials: SS
authors.lastname: Bhat
mesh_terms: D000005:Abdomen / Q000000981:diagnostic imaging; D000310:Adrenal Gland Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000503:physiopathology; D003937:Diagnosis, Differential; D005260:Female; D005729:Ganglioneuroma / Q000175:diagnosis* / Q000473:pathology / Q000503:physiopathology; D006651:Histocytochemistry; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology; D008207:Lymphatic Metastasis; D008875:Middle Aged; D009362:Neoplasm Metastasis / Q000473:pathology; D011860:Radiography, Abdominal; D012186:Retroperitoneal Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000503:physiopathology; D014463:Ultrasonography