title: [Three case reports of effective home palliative chemotherapy with an infuser pump].
abstract: We report three cases of home palliative chemotherapy with an infuser pump (IP) for continuous infusion of anticancer drugs, which is as effective as being treated at the hospital. Cases are: A 74-year-old man with intraperitoneal metastasis after rectal operation, a 43-year-old woman with pelvis metastasis after a uterus cervical operation and a 70-year-old man with gastric cancer and massive metastases of the liver. Their performance status (PS) ranged from 3-4. All cases underwent continuous infusion of cisplatin 20-30 mg/w with IP and CPT-11:10-40 mg/w in 1 hour. For case 1/2, 5-FU 1,750 mg/w was carried out continuously, and TS-1 80 mg/day/body was administered for case 3. After 4 courses of chemotherapy, all cases indicated effective changes such as decrease of pain, reduction of metastatic tumor size, decrease of tumor bleeding and tumor makers. Their quality of life (QOL) improved. Palliative chemotherapy to improve QOL can be performed at home if used with IP for poor PS patients.
authors.affiliation: Dept of Surgery, Koto Hospital.
authors.forename: Haruhiro
authors.initials: H
authors.lastname: Nishina
authors.forename: Toru
authors.initials: T
authors.lastname: Honda
authors.forename: Tomotake
authors.initials: T
authors.lastname: Koizumi
authors.forename: Noriyuki
authors.initials: N
authors.lastname: Murai
authors.forename: Hirohisa
authors.initials: H
authors.lastname: Kato
mesh_terms: D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D004334:Drug Administration Schedule; D005260:Female; D018718:Home Infusion Therapy; D006801:Humans; D008113:Liver Neoplasms / Q000556:secondary; D008175:Lung Neoplasms / Q000556:secondary; D008297:Male; D008875:Middle Aged; D010166:Palliative Care; D010386:Pelvic Neoplasms / Q000188:drug therapy* / Q000556:secondary; D011788:Quality of Life; D012004:Rectal Neoplasms / Q000188:drug therapy* / Q000473:pathology; D013274:Stomach Neoplasms / Q000188:drug therapy* / Q000473:pathology