Lymphoid polyps of the palatine tonsil.
Tonsillar lymphoid polyps are uncommon lesions that have rarely been studied. The authors describe the clinical, histopathologic, and immunohistochemical features of 6 tonsillar polyps in which lymphoid tissue represented more than 80% of the lesion. Presenting symptoms were tonsillar mass and/or dysphagia. No predisposing factor was detected. Microscopically, all polyps contained follicles with germinal centers, crypts lined by lymphoepithelium, and a small amount of fibrous tissue in the center of the lesion. B cells (CD20+), T cells (CD45RO+), plasma cells (kappa+ and lambda+) and vessels (lymphatic, D2-40+; blood, CD34+) presented distribution and architectural patterns as expected for lymphoid tissue of a palatine tonsil. Tonsillar lymphoid polyps are possibly hamartomas characterized by overgrowth of lymphoid elements, which maintain an architectural pattern and cellular composition similar to those of the palatine tonsil.
Barreto
Icleia
I
Department of Pathology, School of Medicine, University of Campinas, Campinas, Brazil.
Juliano
Priscila
P
Chagas
Cristiano
C
Altemani
Albina
A
D000293:Adolescent; D000328:Adult; D015703:Antigens, CD / Q000378:metabolism; D015415:Biomarkers / Q000378:metabolism; D002648:Child; D005260:Female; D006222:Hamartoma / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D006801:Humans; D007150:Immunohistochemistry; D008221:Lymphoid Tissue / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D014066:Palatine Tonsil / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D010608:Pharyngeal Diseases / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D011127:Polyps / Q000378:metabolism / Q000473:pathology* / Q000601:surgery
D015703:Antigens, CD; D015415:Biomarkers