Two Dutch brothers with Borrone dermato-cardio-skeletal syndrome.
In 1993, Borrone et al. described two Italian brothers affected by a syndrome of severe acne, mitral valve prolapse, dysmorphic facies, and Scheuermann-like changes of the vertebral column. Since then, no further cases have been reported. Here, we report on two Dutch brothers with many features suggestive of this rare syndrome.
van Steensel
M A M
MA
Department of Dermatology, University Hospital Maastricht, Maastricht, The Netherlands. mvst@sder.azm.nl
Ceulen
R P M
RP
Delhaas
T
T
de Die-Smulders
C
C
D000015:Abnormalities, Multiple / Q000473:pathology*; D000293:Adolescent; D000328:Adult; D001699:Biometry; D006225:Hand / Q000000981:diagnostic imaging; D006801:Humans; D008297:Male; D009426:Netherlands; D010641:Phenotype; D011859:Radiography; D035781:Siblings; D012886:Skull / Q000000981:diagnostic imaging; D013577:Syndrome; D044465:White People