title: Gold-catalyzed cyclization of allene-substituted malonate esters: synthesis of beta,gamma-unsaturated delta-lactones.
abstract: An efficient method for the preparation of beta,gamma-unsaturated delta-lactones has been developed. The starting materials for the synthesis of these compounds are allene-substituted malonates which undergo gold-catalyzed cyclization by means of nucleophilic attack of the ester moiety on the allene. It is worth mentioning that this is the first example where an ester group attacks as a nucleophile in a gold-catalyzed transformation of allenes.
authors.affiliation: Department of Organic Chemistry, Arrhenius Laboratory, Stockholm University, SE-106 91 Stockholm, Sweden. jp@organ.su.se
authors.forename: Julio
authors.initials: J
authors.lastname: Piera
authors.forename: Patrik
authors.initials: P
authors.lastname: Krumlinde
authors.forename: Dirk
authors.initials: D
authors.lastname: Strübing
authors.forename: Jan-E
authors.initials: JE
authors.lastname: Bäckvall