title: Effectiveness of intrauterine insemination in subfertile couples with an isolated cervical factor: a randomized clinical trial.
abstract: After randomization of subfertile couples with an isolated cervical factor to intrauterine insemination for 6 months or expectant management for 6 months, 26 women (51%) vs. 16 women (33%) conceived, respectively. Of these pregnancies, 22 (43%) vs. 13 (27%) were ongoing (relative risk, 1.6; 95% confidence interval, 0.91 to 2.8). There was one multiple pregnancy in the group that was allocated to intrauterine insemination. This trial suggests a beneficial effect of IUI in couples with an isolated cervical factor.
authors.affiliation: Department of Obstetrics and Gynecology, Vrije Universiteit Medical Center, Amsterdam, the Netherlands. pn.steures@amc.uva.nl
authors.forename: Pieternel
authors.initials: P
authors.lastname: Steures
authors.forename: Jan Willem
authors.initials: JW
authors.lastname: van der Steeg
authors.forename: Peter G A
authors.initials: PG
authors.lastname: Hompes
authors.forename: Patrick M M
authors.initials: PM
authors.lastname: Bossuyt
authors.forename: J Dik F
authors.initials: JD
authors.lastname: Habbema
authors.forename: Marinus J C
authors.initials: MJ
authors.lastname: Eijkemans
authors.forename: Willem A
authors.initials: WA
authors.lastname: Schöls
authors.forename: Jan M
authors.initials: JM
authors.lastname: Burggraaff
authors.forename: Fulco
authors.initials: F
authors.lastname: van der Veen
authors.forename: Ben W J
authors.initials: BW
authors.lastname: Mol
mesh_terms: D000328:Adult; D000465:Algorithms; D002584:Cervix Uteri / Q000473:pathology; D005191:Family Characteristics; D005260:Female; D006801:Humans; D007247:Infertility, Female / Q000175:diagnosis / Q000628:therapy*; D007315:Insemination, Artificial / Q000379:methods*; D008297:Male; D011379:Prognosis; D016896:Treatment Outcome