title: Variation in clinical, manometric and endosonographic findings in anterior chronic anal fissure: a prospective study.
abstract: Nearly all chronic anal fissures occur in the posterior midline of the anal canal. However, some of them are in the anterior midline and are rarely double or in the lateral anal walls. The aim of this study was to determine if the clinical, manometric and endosonographic characteristics in patients with chronic anal fissure varied according to topography of the fissure. The patients included in this prospective study were divided according to a fissure site in posterior midline location (Group A, n = 84) and anterior midline location (Group B, n = 30). No differences were found regarding clinical data except that anterior fissures were more common in females. Mean maximal anal resting pressure and internal anal sphincter thickness was higher in Group A. However, these differences were not statistically significant. We found correlation between mean maximal anal resting pressure and internal anal sphincter thickness in patients suffering from anterior chronic anal fissure.
authors.affiliation: Colorectal Surgery Unit, Department of Surgery, Hospital del Mar, Passeig Marítim 25-29, 08003, Barcelona, Spain.
authors.forename: Marta
authors.initials: M
authors.lastname: Pascual
authors.forename: David
authors.initials: D
authors.lastname: Parés
authors.forename: Miguel
authors.initials: M
authors.lastname: Pera
authors.forename: Ricard
authors.initials: R
authors.lastname: Courtier
authors.forename: Maria José
authors.initials: MJ
authors.lastname: Gil
authors.forename: Sonia
authors.initials: S
authors.lastname: Puig
authors.forename: Alejandro
authors.initials: A
authors.lastname: Serrano
authors.forename: Montserrat
authors.initials: M
authors.lastname: Andreu
authors.forename: Luis
authors.initials: L
authors.lastname: Grande
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002908:Chronic Disease; D019160:Endosonography / Q000379:methods*; D005260:Female; D005401:Fissure in Ano / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000503:physiopathology*; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008365:Manometry / Q000379:methods*; D008875:Middle Aged; D005996:Nitroglycerin / Q000008:administration & dosage; D009824:Ointments; D011312:Pressure; D011379:Prognosis; D011446:Prospective Studies; D012720:Severity of Illness Index; D014665:Vasodilator Agents / Q000008:administration & dosage
chemical_list: D009824:Ointments; D014665:Vasodilator Agents; D005996:Nitroglycerin