Dysgerminoma of the ovary with precocious puberty: a case report.
Ovarian dysgerminoma is usually hormonally inert, but when it contains syncytiotrophoblastic giant cells or undergoes malignant transformation, the level of estradiol might be elevated. A 6-year-old girl contracted ovarian dysgerminoma with precocious puberty, and her levels of beta-human chorionic gondaotropin, alpha-fetoprotein and estradiol were high. After resection of the tumor, levels of tumor markers became normal and precocious puberty disappeared. We report this unusual type of dysgerminoma with a brief review of the literature.
Song
Eun-Seop
ES
Department of Obstetrics and Gynecology, Inha University School of Medicine, Incheon, South Korea.
Lee
Jung-Pil
JP
Han
Jae-Ho
JH
Kim
Ho-Yeon
HY
Mun
Se-Hee
SH
Ryu
Hee-Sug
HS
Chang
Ki-Hong
KH
D002648:Child; D003937:Diagnosis, Differential; D004407:Dysgerminoma / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D005260:Female; D006801:Humans; D007813:Laparotomy; D010051:Ovarian Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D011629:Puberty, Precocious; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography