Lamotrigine-induced manic switches have already been reported.
Selek
Salih
S
Savas
Haluk A
HA
D018692:Antimanic Agents / Q000008:administration & dosage / Q000009:adverse effects*; D001714:Bipolar Disorder / Q000139:chemically induced* / Q000175:diagnosis / Q000523:psychology; D003865:Major Depressive Disorder / Q000188:drug therapy*; D006801:Humans; D000077213:Lamotrigine; D014227:Triazines / Q000008:administration & dosage / Q000009:adverse effects*
D018692:Antimanic Agents; D014227:Triazines; D000077213:Lamotrigine