title: Design, synthesis, and structural studies on potent biaryl inhibitors of type II dehydroquinases.
authors.affiliation: Department of Chemistry, University of Cambridge, Lensfield Road, CB2 1EW, Cambridge, UK.
authors.forename: Richard J
authors.initials: RJ
authors.lastname: Payne
authors.forename: Alan
authors.initials: A
authors.lastname: Riboldi-Tunnicliffe
authors.forename: Olivier
authors.initials: O
authors.lastname: Kerbarh
authors.forename: Andrew D
authors.initials: AD
authors.lastname: Abell
authors.forename: Adrian J
authors.initials: AJ
authors.lastname: Lapthorn
authors.forename: Chris
authors.initials: C
authors.lastname: Abell
mesh_terms: D001665:Binding Sites; D001643:Bridged Bicyclo Compounds / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D015195:Drug Design; D004791:Enzyme Inhibitors / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D016480:Helicobacter pylori / Q000201:enzymology; D006836:Hydro-Lyases; D008958:Models, Molecular; D015394:Molecular Structure; D009169:Mycobacterium tuberculosis / Q000201:enzymology; D048372:Streptomyces coelicolor / Q000201:enzymology
chemical_list: D001643:Bridged Bicyclo Compounds; D004791:Enzyme Inhibitors; D006836:Hydro-Lyases; C020000:3-dehydroquinate dehydratase