title: The role of complement and Toll-like receptors in organ transplantation.
abstract: The innate immune system not only participates in host defence but also contributes to the control of adaptive immune responses. Complement and Toll-like receptors (TLR) are key components of innate immunity. Emerging evidence suggests their activation is involved in all major aspects of transplantation. This paper reviews the current understanding of how the complement and TLR on impact transplant injury.
authors.affiliation: Department of Nephrology and Transplantation, King's College London School of Medicine at Guy's, King's College and St Thomas' Hospitals, London, UK.
authors.forename: Tao
authors.initials: T
authors.lastname: Lin
authors.forename: Wuding
authors.initials: W
authors.lastname: Zhou
authors.forename: Steven H
authors.initials: SH
authors.lastname: Sacks
mesh_terms: D003165:Complement System Proteins / Q000276:immunology*; D006801:Humans; D007113:Immunity, Innate; D015427:Reperfusion Injury / Q000276:immunology; D051193:Toll-Like Receptors / Q000276:immunology*; D014180:Transplantation; D014181:Transplantation Immunology; D014184:Transplantation, Homologous / Q000276:immunology
chemical_list: D051193:Toll-Like Receptors; D003165:Complement System Proteins