title: Emergency department management of the salicylate-poisoned patient.
abstract: Salicylate toxicity continues to be encountered commonly in emergency medicine. This article portrays the signs and symptoms of salicylate toxicity, reviews the erratic absorption and elimination kinetics, describes the devastating physiologic effects of overdose, and illustrates the potentially subtle manifestations of chronic aspirin toxicity.
authors.affiliation: Division of Toxicology, Albert Einstein Medical Center, Philadelphia, PA 19141, USA. omalleyg@einstein.edu
authors.forename: Gerald F
authors.initials: GF
authors.lastname: O'Malley
mesh_terms: D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000097:blood / Q000493:pharmacokinetics / Q000506:poisoning*; D001241:Aspirin / Q000097:blood / Q000493:pharmacokinetics / Q000506:poisoning; D062787:Drug Overdose / Q000175:diagnosis / Q000503:physiopathology; D004636:Emergency Service, Hospital; D006801:Humans; D006435:Renal Dialysis; D012151:Resuscitation / Q000379:methods*; D012459:Salicylates / Q000097:blood / Q000493:pharmacokinetics / Q000506:poisoning*
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D012459:Salicylates; D001241:Aspirin