Fluorous 2-Chloropyridinium Salt (Mukaiyama Condensation Reagent) for Amide Formation Reactions.
A new fluorous 2-chloropyridinium hexafluorophosphate was prepared as a modified Mukaiyama condensation reagent, and it was applied in amide formation reactions. Good to excellent purities of amides were obtained after fluorous solid-phase extraction of reaction mixtures without additional chromatography.
Nagashima
Tadamichi
T
Fluorous Technologies Inc., University of Pittsburgh Applied Research Center, 970 William Pitt Way, Pittsburgh, PA 15238, USA.
Lu
Yimin
Y
Petro
Michael J
MJ
Zhang
Wei
W