Recoverable PEG-supported copper catalyst for highly stereocontrolled nitroaldol condensation.
A new poly(ethylene glycol)-modified DAT2-Cu(OAc)2 complex smoothly catalyzes a base-free nitroaldol condensation in a highly enantioselective manner (ee up to 93%) also in reagent-grade solvent and in the presence of air. Effective recovery and recycling (up to five runs) of supported catalysts are documented.
Bandini
Marco
M
Dipartimento di Chimica G. Ciamician, Università di Bologna, via Selmi 2, 40126 Bologna, Italy. marco.bandini@unibo.it
Benaglia
Maurizio
M
Sinisi
Riccardo
R
Tommasi
Simona
S
Umani-Ronchi
Achille
A