title: Experience-dependent rescaling of entorhinal grids.
abstract: The firing pattern of entorhinal 'grid cells' is thought to provide an intrinsic metric for space. We report a strong experience-dependent environmental influence: the spatial scales of the grids (which are aligned and have fixed relative sizes within each animal) vary parametrically with changes to a familiar environment's size and shape. Thus grid scale reflects an interaction between intrinsic, path-integrative calculation of location and learned associations to the external environment.
authors.affiliation: Institute of Cognitive Neuroscience, University College London, 17 Queen Square, London WC1N 3AR, UK.
authors.forename: Caswell
authors.initials: C
authors.lastname: Barry
authors.forename: Robin
authors.initials: R
authors.lastname: Hayman
authors.forename: Neil
authors.initials: N
authors.lastname: Burgess
authors.forename: Kathryn J
authors.initials: KJ
authors.lastname: Jeffery
mesh_terms: D000200:Action Potentials / Q000502:physiology; D000818:Animals; D001522:Behavior, Animal; D001931:Brain Mapping; D018728:Entorhinal Cortex / Q000166:cytology*; D008297:Male; D008568:Memory / Q000502:physiology*; D008959:Models, Neurological; D009474:Neurons / Q000502:physiology*; D009949:Orientation; D010775:Photic Stimulation; D051381:Rats; D013028:Space Perception / Q000502:physiology*