Severe systemic adverse reaction to proton pump inhibitors in an infant.
Episodes of respiratory distress with chest retraction and wheezing, sometimes associated with facial edema, were noted after administering the proton pump inhibitors omeprazole and esomeprazole in an infant with gastroesophageal reflux. The disturbances relieved dramatically after withdrawing the proton pump inhibitor.
Baldassarre
Emanuele
E
Division of Pediatric Surgery, Ospedale San Giovanni, Bellinzona, Switzerland.
Sagaon
Mario Mendoza
MM
Ferrarini
Alessandra
A
Bianchetti
Mario G
MG
D004791:Enzyme Inhibitors / Q000009:adverse effects*; D064098:Esomeprazole; D005260:Female; D005764:Gastroesophageal Reflux / Q000188:drug therapy / Q000601:surgery; D006801:Humans; D007223:Infant; D008171:Lung Diseases / Q000139:chemically induced* / Q000175:diagnosis; D009853:Omeprazole / Q000009:adverse effects*; D054328:Proton Pump Inhibitors; D012135:Respiratory Sounds / Q000209:etiology
D004791:Enzyme Inhibitors; D054328:Proton Pump Inhibitors; D009853:Omeprazole; D064098:Esomeprazole