Unusual clinical presentation of amyloidosis: bilateral stenosis of the external auditory canal, hoarseness and a rapid course of cutaneous lesions.
We report a patient with multiple myeloma associated with primary systemic amyloidosis who had a rapid evolution and a very unusual form of presentation. The association of amyloidosis in patients with multiple myeloma is 15%, and clinically evident mucocutaneous involvement occurs in up to 40% of patients.
Alvarez-Ruiz
S B
SB
Department of Dermatology, Hospital Universitario La Princesa Diego de León 62, Madrid, Spain
Pérez-Gala
S
S
Aragüés
M
M
Fraga
J
J
García-Díez
A
A
D000686:Amyloidosis / Q000150:complications* / Q000175:diagnosis; D003251:Constriction, Pathologic / Q000209:etiology; D003937:Diagnosis, Differential; D004424:Ear Canal / Q000002:abnormalities*; D004426:Ear Deformities, Acquired / Q000209:etiology; D005260:Female; D006685:Hoarseness / Q000209:etiology*; D006801:Humans; D008875:Middle Aged; D009101:Multiple Myeloma / Q000150:complications / Q000175:diagnosis; D012871:Skin Diseases / Q000209:etiology*