title: Xp11 translocation carcinoma of the kidney presenting with multilocular cystic renal cell carcinoma-like features.
abstract: Reported is the case of a 17-year-old girl with a multicystic tumor in the middle of the right kidney. Partial nephrectomy revealed an epithelial neoplasm with multilocular cystic renal cell carcinoma pattern. The cells exhibited strong nuclear reactivity for TFE3 protein and supported the diagnosis of Xp11 translocation carcinoma of the kidney. A similar case has not been found in the literature. The example emphasizes the high index of suspicion needed for an accurate diagnosis of renal carcinomas.
authors.affiliation: Laborclin Lab, School of Medicine, São José do Rio Preto, SP, Brazil. larpac@riopreto.com.br
authors.forename: Sueli
authors.initials: S
authors.lastname: Suzigan
authors.forename: Ricardo
authors.initials: R
authors.lastname: Drut
authors.forename: Paulo
authors.initials: P
authors.lastname: Faria
authors.forename: Pedram
authors.initials: P
authors.lastname: Argani
authors.forename: Angelo M
authors.initials: AM
authors.lastname: De Marzo
authors.forename: Rui Nogueira
authors.initials: RN
authors.lastname: Barbosa
authors.forename: Eliseu Roberto
authors.initials: ER
authors.lastname: Mello Denadai
authors.forename: Júlio
authors.initials: J
authors.lastname: Martins-Filho
authors.forename: Rubens Carlos
authors.initials: RC
authors.lastname: Martucci
authors.forename: Tufik
authors.initials: T
authors.lastname: Bauab
mesh_terms: D000293:Adolescent; D051778:Basic Helix-Loop-Helix Leucine Zipper Transcription Factors / Q000378:metabolism; D002292:Carcinoma, Renal Cell / Q000235:genetics* / Q000378:metabolism / Q000473:pathology; D002467:Cell Nucleus / Q000378:metabolism / Q000473:pathology; D002878:Chromosomes, Human, Pair 1; D041321:Chromosomes, Human, X; D005260:Female; D006801:Humans; D007680:Kidney Neoplasms / Q000235:genetics* / Q000378:metabolism / Q000473:pathology; D009392:Nephrectomy; D014178:Translocation, Genetic
chemical_list: D051778:Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; C069203:TFE3 protein, human