title: Spontaneous neoplasia in the baboon (Papio spp.).
abstract: BACKGROUND
  There are several comprehensive reviews of spontaneous neoplasia in non-human primates that compile individual cases or small numbers of cases, but do not provide statistical analysis of tumor incidence, demographics, or epidemiology.
  
  
  METHODS
  This paper reports all spontaneous neoplasms (n = 363) diagnosed over a 15-year period in a baboon colony with an average annual colony population of 4000.
  
  
  RESULTS
  A total of 363 spontaneous neoplasms were diagnosed in 313 baboons: 77 cases were males (25%) and 236 were females (75%); ages ranged from 1 month to 33 years (mean 16.5, median 17).
  
  
  CONCLUSIONS
  The organ systems affected in descending order of number of neoplasms were hematopoietic organs (n = 101, 28%), urogenital tract (n = 78, 21%), integument (n = 43, 12%), alimentary tract (n = 43, 12%), endocrine organs (n = 40, 11%), nervous system (n = 33, 9%), musculoskeletal system (n = 5, 1%), and respiratory system (n = 4, 1%). Malignant cases numbered 171 (47%); 192 (53%) cases were benign.
authors.affiliation: Southwest National Primate Research Center at Southwest Foundation for Biomedical Research, San Antonio, TX, USA.
authors.forename: Rachel E
authors.initials: RE
authors.lastname: Cianciolo
authors.forename: Stephanie D
authors.initials: SD
authors.lastname: Butler
authors.forename: Jeffery S
authors.initials: JS
authors.lastname: Eggers
authors.forename: Edward J
authors.initials: EJ
authors.lastname: Dick
authors.forename: M Michelle
authors.initials: MM
authors.lastname: Leland
authors.forename: Melissa
authors.initials: M
authors.lastname: de la Garza
authors.forename: Kathleen M
authors.initials: KM
authors.lastname: Brasky
authors.forename: Larry B
authors.initials: LB
authors.lastname: Cummins
authors.forename: Gene B
authors.initials: GB
authors.lastname: Hubbard
mesh_terms: D000818:Animals; D000830:Animals, Laboratory; D005260:Female; D015994:Incidence; D008297:Male; D008992:Monkey Diseases / Q000453:epidemiology*; D009369:Neoplasms / Q000453:epidemiology / Q000662:veterinary*; D010215:Papio; D013781:Texas / Q000453:epidemiology