title: Fat graft myringoplasty after unsuccessful tympanic membrane repair.
abstract: The objective of the present study was to evaluate the efficacy of fat graft myringoplasty in repairing residual or recurrent tympanic membrane perforation. A retrospective analysis was performed on 31 patients, aged 25-57 years (mean 43.3), submitted to myringoplasty revision using fat graft. Fourteen were males and 17 females. Perforation size ranged from 1 to 5 mm. Follow-up time ranged from 4 to 62 months (mean 26 months). Fat graft myringoplasty was performed under local anesthesia, using ear lobe fat in 26 patients and abdominal fat in five patients closure of tympanic membrane perforation was achieved in 87.1% of ears. No modification of the hearing level was evidenced at the statistical analysis. Fat graft myringoplasty is a safe, effective and minimally invasive procedure, suitable to repair small residual/recurrent perforations of the tympanic membrane. The angiogenic properties of the fat are ideal to overcome the poor vascular supply in the vicinity of the tympanic membrane perforation.
authors.affiliation: Department of Otolaryngology, Civil Hospital Borgo Trento, Verona, Italy. franco.fiorino@virgilio.it
authors.forename: Francesco
authors.initials: F
authors.lastname: Fiorino
authors.forename: Franco
authors.initials: F
authors.lastname: Barbieri
mesh_terms: D000273:Adipose Tissue / Q000637:transplantation*; D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009225:Myringoplasty / Q000379:methods*; D013517:Otorhinolaryngologic Surgical Procedures; D011183:Postoperative Complications / Q000601:surgery*; D012086:Reoperation; D017211:Treatment Failure; D018058:Tympanic Membrane Perforation / Q000601:surgery*