[Genetic structure of X-STR loci of Ewenki nationality and its affinity with other nationalities].
OBJECTIVE
To determine the genetic diversity of X-TR loci, and to evaluate the genetic structure X chromosome's of Ewenki nationality and its affinity with other nationalities.


METHODS
We chose 9 X-TR (DXS6804, DXS7133, DXS101, DXS6789, DXS6799, DXS7423, HPRTB, DXS8378, DXS7132) as genetic markers from 99 irrelative individules to determine the genetic diversity of Ewenki in Inner Mongolian. Cluster analysis and phylogenic trees was applied to show the genetic distance among the nationalities.


RESULTS
We got 51 alleles in the studied population, with the frequency diverse between 0.0109 and 0.6863. Genotype frequency was from 0.0217 to 0.3778. Heterozygosity(H),the power of discrimination(PD) and the polymorphism information conten (PIC) were consistent with the forensic application. Cluster analysis and phylogenic trees revealed that Ewenki nationality had estrangement genetic affinity with the other 3 major nationalities in inner mongolia and Han nationality in Xi'an.


CONCLUSIONS
The genetic information demonstrates that the 9 chosen gene makers were highly informative loci and are suitable for population genetics research and forensic application.
Hou
Qiao-Fang
QF
Medical College of Xi'an Jiaotong University, Key Laboratory of National Ministry of Health for Forensic Sciences, Xi'an, China.
Li
Xiao-Zhong
XZ
Tong
Mu-Er
ME
Rong
Liao-Jiang
LJ
Zhang
Ran
R
Wang
Xu-Jun
XJ
Li
Sheng-Bin
SB
D002681:China; D041321:Chromosomes, Human, X / Q000235:genetics*; D016000:Cluster Analysis; D005006:Ethnicity / Q000145:classification / Q000235:genetics; D005260:Female; D005787:Gene Frequency; D005819:Genetic Markers / Q000235:genetics*; D014644:Genetic Variation; D005838:Genotype; D006801:Humans; D008297:Male; D018895:Microsatellite Repeats / Q000235:genetics*; D010802:Phylogeny; D011110:Polymorphism, Genetic
D005819:Genetic Markers