[Ventilation-perfusion distributions in the lungs. A novel technique for rapid measurement].
The multiple inert gas elimination technique (MIGET) represents the gold standard for analysis of ventilation and perfusion distributions in the lung. Modification of this technique allows a much simpler sample processing and hence permits routine clinical application of this technique. MIGET using micropore membrane inlet mass spectrometry (MMIMS) might, therefore, facilitate early diagnosis of lung diseases and monitoring of therapeutic interventions in the future.
Dünges
B
B
Klinik für Anästhesiologie, Johannes-Gutenberg-Universität, Langenbeckstr. 1, 55131 Mainz. duenges@anaesthesie.klinik.uni-mainz.de
Karmrodt
J
J
Baumgardner
J E
JE
Markstaller
K
K
D000818:Animals; D006801:Humans; D008168:Lung / Q000503:physiopathology*; D008171:Lung Diseases / Q000175:diagnosis / Q000503:physiopathology; D013058:Mass Spectrometry; D008851:Micropore Filters; D005741:Noble Gases; D011652:Pulmonary Circulation / Q000502:physiology*; D015203:Reproducibility of Results; D012129:Respiratory Function Tests
D005741:Noble Gases