title: Maternal derivative chromosome 9 and recurrent pregnancy loss.
abstract: OBJECTIVE
  To disclose the relationship between a derivative chromosome 9 and recurrent pregnancy loss.
  
  
  METHODS
  Case report.
  
  
  METHODS
  Referral from primary clinical care to tertiary hospital for further intervention.
  
  
  METHODS
  A 31-year-old woman who had four recurrent early spontaneous abortions.
  
  
  METHODS
  Cytogenetic and fluorescence in situ hybridization analyses of the chromosome harvested from peripheral blood sample.
  
  
  METHODS
  Karyotype of the patient.
  
  
  RESULTS
  The patient has a unique derivative chromosome 9, der(9)(9qter-->9p24::9p24-->9p11::9p13-->9qter). ish der(9) (CEP9x1,43N6x1,D9Z3x1).
  
  
  CONCLUSIONS
  Maternal derivative chromosome 9 may cause recurrent pregnancy loss.
authors.affiliation: Department of Obstetrics and Gynecology, National Cheng Kung University, College of Medicine, Tainan, Taiwan. lckuan@kgh.com.tw
authors.forename: Ling-Wei
authors.initials: LW
authors.lastname: Chang
authors.forename: I-Wen
authors.initials: IW
authors.lastname: Lee
authors.forename: Pao-Lin
authors.initials: PL
authors.lastname: Kuo
authors.forename: Long-Ching
authors.initials: LC
authors.lastname: Kuan
mesh_terms: D000026:Abortion, Habitual / Q000235:genetics*; D000328:Adult; D002869:Chromosome Aberrations; D002899:Chromosomes, Human, Pair 9; D005260:Female; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D007621:Karyotyping; D011247:Pregnancy