title: A new expiratory support system for resolving air trapping in lungs during mechanical ventilation: a lung model study.
abstract: The aim of the study was to assess a new expiratory support (ES) system in resolving air trapping in the lungs during mechanical ventilation. The ES system consisted of a cylinder and two valves that were connected to the ventilatory circuit. The movements of them were synchronized with the ventilator. The cylinder aspirated gas during expiration. We compared the effects of the ES on air trapping between a narrower and an ordinary size endotracheal tube (ETT) (internal diameter (ID): 5 and 8 mm). In addition, we compared the effects of the ES on air trapping between normal and high airway resistance of the lungs (5 and 20 cm H(2)O/L/s). The ventilatory settings were as follows: volume controlled ventilation with constant inspiratory flow rate; tidal volume, 0.5 L; inspiratory time, 1.0 s; expiratory time, 1.0, 1.5, or 2.0 s; and PEEP, 0 cm H(2)O. The ES normalized the end-expiratory alveolar pressure of the 5 mm ID ETT at a level similar to that of the 8 mm ID ETT. The ES also resolved the air trapping induced by the high airway resistance of the lungs. In conclusion, the ES system resolved the air trapping associated with a narrow endotracheal tube and high airway resistance of the lungs.
authors.affiliation: Osaka University Hospital Intensive Care Unit, Osaka, Japan. auchiyama@hp-icu.med.oska-u.ac.jp
authors.forename: Akinori
authors.initials: A
authors.lastname: Uchiyama
authors.forename: Masaji
authors.initials: M
authors.lastname: Nishimura
authors.forename: Mitsuyuki
authors.initials: M
authors.lastname: Amata
authors.forename: Takashi
authors.initials: T
authors.lastname: Mashimo
authors.forename: Yuji
authors.initials: Y
authors.lastname: Fujino
mesh_terms: D000388:Air; D000465:Algorithms; D045853:Exhalation / Q000502:physiology*; D006801:Humans; D007442:Intubation, Intratracheal / Q000295:instrumentation; D007564:Japan; D008168:Lung / Q000502:physiology*; D008954:Models, Biological; D012121:Respiration, Artificial / Q000295:instrumentation*; D013673:Technology Assessment, Biomedical