title: Laparoscopic partial adrenalectomy for bilateral cortisol-secreting adenomas.
abstract: Bilateral cortisol-secreting adenomas are a rare cause of Cushing's syndrome. We report a case of a 35-year-old woman who presented with ACTH-independent Cushing's syndrome and bilateral adrenal adenomas. Adrenal venous sampling confirmed both adenomas to be hyper-secreting cortisol. She underwent bilateral laparoscopic adrenalectomy; total right and partial left adrenalectomies. At 2-year follow-up, she is maintained on low-dose fludrocortisone and hydrocortisone, and without recurrence of hypercorticolism. Laparoscopic partial adrenalectomy is a feasible option for this rare condition; however, long-term follow-up is needed to determine her total independence from steroid usage.
authors.affiliation: Endocrine Surgery Service, Department of Surgery, National University Hospital, Singapore.
authors.forename: Jeffrey P
authors.initials: JP
authors.lastname: Domino
authors.forename: Siok Bee
authors.initials: SB
authors.lastname: Chionh
authors.forename: Davide
authors.initials: D
authors.lastname: Lomanto
authors.forename: Avinash N
authors.initials: AN
authors.lastname: Katara
authors.forename: Abu
authors.initials: A
authors.lastname: Rauff
authors.forename: Wei-Keat
authors.initials: WK
authors.lastname: Cheah
mesh_terms: D049913:ACTH-Secreting Pituitary Adenoma / Q000378:metabolism / Q000601:surgery*; D000310:Adrenal Gland Neoplasms / Q000378:metabolism / Q000601:surgery*; D000315:Adrenalectomy; D000328:Adult; D005260:Female; D006801:Humans; D006854:Hydrocortisone / Q000378:metabolism; D010535:Laparoscopy
chemical_list: D006854:Hydrocortisone