title: [Prevalence of Helicobacter pylori CaGa strains and peptic ulcer in the population of Eastern Siberia].
abstract: OBJECTIVE
  To study prevalence of Helicobacter pylori (Hp) CagA strains and ulcer disease in native population of eastern Siberia and migrants.
  
  
  METHODS
  Epidemiological screening of Hp CagA strains and ulcer disease was performed by cross-sectional method in population of Evenkia, Khakassia, Tuva. Fibrogastroduodenoscopy was made in 3602 examinees; IgG of CagA Hp was detected in the sera of 2472 patients with entyme immunoassay.
  
  
  RESULTS
  Prevalence of ulcer was higher in Europeans than in Mongoloids. Detectability of CagA Hp was 36.5% among khakas population, 43.8% among evenks, 60.1% among tyvin population, 59.8% among European population. In khakas and tyva population with ulcer CagA Hp incidence was higher than in healthy subjects. CONCLUSION. CagA HP is associated with ulcer in mongoloid population. This was not confirmed for European populatioin of the Eastern Siberia.
authors.forename: V V
authors.initials: VV
authors.lastname: Tsukanov
authors.forename: S V
authors.initials: SV
authors.lastname: Barkalov
authors.forename: Iu L
authors.initials: IuL
authors.lastname: Tonkikh
authors.forename: O V
authors.initials: OV
authors.lastname: Shtygasheva
authors.forename: A E
authors.initials: AE
authors.lastname: Barmakov
authors.forename: E P
authors.initials: EP
authors.lastname: Bronnikova
authors.forename: O S
authors.initials: OS
authors.lastname: Amel'chugova
mesh_terms: D000328:Adult; D005260:Female; D014943:Global Health; D016481:Helicobacter Infections / Q000453:epidemiology / Q000276:immunology / Q000382:microbiology; D016480:Helicobacter pylori / Q000145:classification* / Q000302:isolation & purification*; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood / Q000276:immunology*; D015994:Incidence; D008297:Male; D011159:Population Surveillance / Q000379:methods; D015995:Prevalence; D012800:Siberia / Q000453:epidemiology
chemical_list: D007074:Immunoglobulin G