title: Lymphoid polyps of the palatine tonsil.
abstract: Tonsillar lymphoid polyps are uncommon lesions that have rarely been studied. The authors describe the clinical, histopathologic, and immunohistochemical features of 6 tonsillar polyps in which lymphoid tissue represented more than 80% of the lesion. Presenting symptoms were tonsillar mass and/or dysphagia. No predisposing factor was detected. Microscopically, all polyps contained follicles with germinal centers, crypts lined by lymphoepithelium, and a small amount of fibrous tissue in the center of the lesion. B cells (CD20+), T cells (CD45RO+), plasma cells (kappa+ and lambda+) and vessels (lymphatic, D2-40+; blood, CD34+) presented distribution and architectural patterns as expected for lymphoid tissue of a palatine tonsil. Tonsillar lymphoid polyps are possibly hamartomas characterized by overgrowth of lymphoid elements, which maintain an architectural pattern and cellular composition similar to those of the palatine tonsil.
authors.affiliation: Department of Pathology, School of Medicine, University of Campinas, Campinas, Brazil.
authors.forename: Icleia
authors.initials: I
authors.lastname: Barreto
authors.forename: Priscila
authors.initials: P
authors.lastname: Juliano
authors.forename: Cristiano
authors.initials: C
authors.lastname: Chagas
authors.forename: Albina
authors.initials: A
authors.lastname: Altemani
mesh_terms: D000293:Adolescent; D000328:Adult; D015703:Antigens, CD / Q000378:metabolism; D015415:Biomarkers / Q000378:metabolism; D002648:Child; D005260:Female; D006222:Hamartoma / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D006801:Humans; D007150:Immunohistochemistry; D008221:Lymphoid Tissue / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D014066:Palatine Tonsil / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D010608:Pharyngeal Diseases / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D011127:Polyps / Q000378:metabolism / Q000473:pathology* / Q000601:surgery
chemical_list: D015703:Antigens, CD; D015415:Biomarkers