The CD95 receptor: apoptosis revisited.
CD95 is the quintessential death receptor and, when it is bound by ligand, cells undergo apoptosis. Recent evidence suggests, however, that CD95 mediates not only apoptosis but also diverse nonapoptotic functions depending on the tissue and the conditions.
Peter
Marcus E
ME
Ben May Department for Cancer Research, University of Chicago, Chicago, IL 60637, USA. mpeter@uchicago.edu <mpeter@uchicago.edu>
Budd
Ralph C
RC
Desbarats
Julie
J
Hedrick
Stephen M
SM
Hueber
Anne-Odile
AO
Newell
M Karen
MK
Owen
Laurie B
LB
Pope
Richard M
RM
Tschopp
Juerg
J
Wajant
Harald
H
Wallach
David
D
Wiltrout
Robert H
RH
Zörnig
Martin
M
Lynch
David H
DH
D000818:Animals; D017209:Apoptosis; D053222:Fas Ligand Protein / Q000378:metabolism; D006801:Humans; D051379:Mice; D009369:Neoplasms / Q000276:immunology / Q000378:metabolism; D015398:Signal Transduction; D019014:fas Receptor / Q000378:metabolism*
D053222:Fas Ligand Protein; D019014:fas Receptor