A concise synthesis of eupomatilones 4, 6, and 7 by rhodium-catalyzed enantioselective desymmetrization of cyclic meso anhydrides with organozinc reagents generated in situ.
Johnson
Jeffrey B
JB
Department of Chemistry, Colorado State University, Fort Collins, CO 80523, USA.
Bercot
Eric A
EA
Williams
Catherine M
CM
Rovis
Tomislav
T
D000812:Anhydrides / Q000737:chemistry*; D001572:Benzofurans / Q000138:chemical synthesis*; D001688:Biological Products / Q000138:chemical synthesis; D002384:Catalysis; D017705:Lignans / Q000138:chemical synthesis*; D009942:Organometallic Compounds / Q000737:chemistry; D010936:Plant Extracts / Q000138:chemical synthesis; D012238:Rhodium / Q000737:chemistry*; D013237:Stereoisomerism; D015032:Zinc / Q000737:chemistry
D000812:Anhydrides; D001572:Benzofurans; D001688:Biological Products; D017705:Lignans; D009942:Organometallic Compounds; D010936:Plant Extracts; C502383:eupomatilone 4; C522861:eupomatilone 7; C485126:eupomatilone-6; D012238:Rhodium; D015032:Zinc