title: An evaluation of the effects of renal artery stenting in renovascular hypertension.
abstract: Renal artery stenosis is a common cause (1-6%) of secondary hypertension. Renal artery stenting has recently been employed as an adjunct to antihypertensive medication. We evaluated 92 patients who underwent renal angiography of whom 30 were stented. There was a reduction (p < 0.01) in blood pressure immediately post renal artery stenting--systolic BP from 157 +/- 20 to 140 +/- 21 mmHg and diastolic BP from 81 +/- 13 to 72 +/- 12 mmHg was sustained at 6 months follow up (148 +/- 20/76 +/- 12 mmHg) in the outpatients' clinic. The amount of antihypertensive medication did not differ post stenting--2.7 +/- 1.2 pre vs 2.7 +/- 1.2 drugs post procedure. Renal artery stenting did not provide a 'cure' for any patient with atherosclerotic renovascular hypertension and until the results of randomized studies are known we believe use should be restricted.
authors.affiliation: Department of Pharmacology and Therapeutics, St James's Hospital, Dublin. drgeorgemak@yahoo.com
authors.forename: G
authors.initials: G
authors.lastname: Mak
authors.forename: C Y
authors.initials: CY
authors.lastname: Tan
authors.forename: O
authors.initials: O
authors.lastname: Ben Khiaron
authors.forename: N
authors.initials: N
authors.lastname: McEniff
authors.forename: J
authors.initials: J
authors.lastname: Feely
mesh_terms: D000368:Aged; D001794:Blood Pressure; D019917:Blood Vessel Prosthesis Implantation; D018450:Disease Progression; D005260:Female; D006760:Hospitalization; D006801:Humans; D006978:Hypertension, Renovascular / Q000209:etiology / Q000601:surgery*; D007494:Ireland; D008297:Male; D008875:Middle Aged; D017063:Outcome Assessment, Health Care; D012077:Renal Artery / Q000473:pathology / Q000601:surgery; D012078:Renal Artery Obstruction / Q000150:complications / Q000601:surgery*; D015607:Stents