Mosaic chromosome 6 trisomy in an epidermal nevus.
We report a 2-year-old boy with a linear epidermal nevus. Mosaicism for chromosome 6 in skin fibroblasts of affected skin was discovered. Trisomy 6 has not been previously implicated as an isolated finding in epidermal nevi or cutaneous mosaicism.
Sobey
Glenda J
GJ
Skin Genetics Clinic, Sheffield Genetic Services, Sheffield Children's Hospital, Sheffield, UK. glenda.sobey@sch.nhs.uk
Quarrell
Oliver W
OW
Williams
Steven
S
McGrath
Helen M
HM
D002675:Child, Preschool; D002896:Chromosomes, Human, Pair 6 / Q000235:genetics*; D006801:Humans; D008297:Male; D009030:Mosaicism; D009506:Nevus / Q000235:genetics* / Q000473:pathology; D012878:Skin Neoplasms / Q000235:genetics* / Q000473:pathology; D014314:Trisomy / Q000175:diagnosis*