Anti-ganglioside antibodies-mediated leptospiral meningomyeloencephalopolyneuritis.
A case of leptospirosis complicated with meningo-myelo-encephalo-polyneuritis and nephrotic syndrome is presented. Anti-ganglioside antibodies were detected for the first time in a patient with neurological complications of leptospirosis. Possible pathogenic mechanisms and treatment options of these rare manifestations are discussed.
Lepur
Dragan
D
Department of Neuroinfections and Intensive Care Medicine, University Hospital for Infectious Diseases 'Dr. Fran Mihaljevic', Mirogojska, Zagreb. Croatia. lepurix@inet.hr
Himbele
Josip
J
Klinar
Igor
I
Vranjican
Zoran
Z
Barsic
Bruno
B
D000368:Aged; D000906:Antibodies / Q000097:blood; D005732:Gangliosides / Q000276:immunology*; D006801:Humans; D007919:Leptospira / Q000472:pathogenicity*; D007922:Leptospirosis / Q000150:complications*; D008297:Male; D008590:Meningoencephalitis / Q000276:immunology* / Q000382:microbiology; D009404:Nephrotic Syndrome / Q000382:microbiology; D009443:Neuritis / Q000276:immunology* / Q000382:microbiology
D000906:Antibodies; D005732:Gangliosides