title: [En bloc transplantation of pediatric donor kidneys to adult receptors].
abstract: OBJECTIVE
  Analysis of all pediatric donor en bloc transplants to adult receptors performed in our department.
  
  
  METHODS
  Retrospective analysis of 73 en bloc kidney transplants and 497 adult transplants performed in our centre from 1990 to 2004. Mean follow-up was 50.23 months (10.18-89.05 months). All patients received the same immunosuppression, although it evolved with time.
  
  
  RESULTS
  There were significant differences in terms of nonfunctioning kidneys and delayed graft function, more frequent in pediatric en bloc and adult transplants, respectively. Pediatric kidneys provided better renal function and less proteinuria. Patient and graft survivals were similar in both groups. One and five-year graft survivals were 83.56% and 8 1.47% for pediatric donor kidneys, and 91.50% and 86.99% for adult donor kidneys. Vascular complications were the most frequent cause of graft loss for the en bloc transplants.
  
  
  CONCLUSIONS
  Pediatric donor en bloc transplants have an excellent survival and function in the middle and long-term. Vascular complications are the main cause of pediatric donor graft loss. The adoption of a pediatric donor en bloc transplant program increases the transplant activity.
authors.affiliation: Servicios de Urología y Cirugia General, Hospital Clinico San Carlos, Madrid, España. dr_emilio_hernandez@hotmail.com
authors.forename: José Emilio
authors.initials: JE
authors.lastname: Hernández Sánchez
authors.forename: Angel
authors.initials: A
authors.lastname: Gómez Vegas
authors.forename: Jesús
authors.initials: J
authors.lastname: Blázquez Izquierdo
authors.forename: Juan
authors.initials: J
authors.lastname: Grimalt Alvarez
authors.forename: María Jesús
authors.initials: MJ
authors.lastname: Pérez Contín
authors.forename: Manuel
authors.initials: M
authors.lastname: Rabadán Marina
authors.forename: Luis
authors.initials: L
authors.lastname: San José Manso
authors.forename: Miguel
authors.initials: M
authors.lastname: Alonso Prieto
authors.forename: Natalia
authors.initials: N
authors.lastname: Pérez Romero
authors.forename: Angel
authors.initials: A
authors.lastname: Silmi Moyano
mesh_terms: D000328:Adult; D000367:Age Factors; D002648:Child; D002675:Child, Preschool; D005260:Female; D006085:Graft Survival; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D007223:Infant; D053208:Kaplan-Meier Estimate; D016030:Kidney Transplantation / Q000379:methods*; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000453:epidemiology; D012189:Retrospective Studies; D013030:Spain; D016019:Survival Analysis; D014019:Tissue Donors; D009927:Tissue and Organ Procurement; D016896:Treatment Outcome
chemical_list: D007166:Immunosuppressive Agents