The role of mitochondria in stem cell biology.
This mini-review summarizes the current literature on the role of mitochondrial DNA mutations and mitochondrial metabolism in stem cell biology. The possible uses of stem cells as a therapeutic tool in mitochondrial disorders are also reported.
Nesti
Claudia
C
CUCCS (Center for the Clinical Use of Stem Cells) and Department of Neurosciences, Section of Neurology, University of Pisa, Via Roma 67, Pisa, 56126, Italy. cla_nesti@yahoo.it
Pasquali
Livia
L
Vaglini
Francesca
F
Siciliano
Gabriele
G
Murri
Luigi
L
D004272:DNA, Mitochondrial / Q000235:genetics; D006801:Humans; D008928:Mitochondria / Q000502:physiology*; D028361:Mitochondrial Diseases / Q000235:genetics / Q000628:therapy; D009154:Mutation; D033581:Stem Cell Transplantation; D013234:Stem Cells / Q000166:cytology / Q000378:metabolism / Q000502:physiology*
D004272:DNA, Mitochondrial