title: Idiopathic transverse myelitis: corticosteroids, plasma exchange, or cyclophosphamide.
abstract: Transverse myelitis is a focal disorder of the spinal cord in which an immune-mediated process results in neural injury. In this large retrospective study, we compare patients who received one of four treatments to identify the most effective therapies. We identified subsets of patients who received clinical benefit from plasma exchange or cyclophosphamide being included in their treatment regimen.
authors.affiliation: Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21287-5371, USA. bgreenb7@jhmi.edu
authors.forename: B M
authors.initials: BM
authors.lastname: Greenberg
authors.forename: K P
authors.initials: KP
authors.lastname: Thomas
authors.forename: C
authors.initials: C
authors.lastname: Krishnan
authors.forename: A I
authors.initials: AI
authors.lastname: Kaplin
authors.forename: P A
authors.initials: PA
authors.lastname: Calabresi
authors.forename: D A
authors.initials: DA
authors.lastname: Kerr
mesh_terms: D000305:Adrenal Cortex Hormones / Q000008:administration & dosage*; D000328:Adult; D001327:Autoimmune Diseases / Q000150:complications / Q000276:immunology; D015984:Causality; D003520:Cyclophosphamide / Q000008:administration & dosage*; D004185:Disability Evaluation; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage; D007275:Injections, Intravenous; D008297:Male; D008875:Middle Aged; D009188:Myelitis, Transverse / Q000188:drug therapy* / Q000276:immunology / Q000503:physiopathology; D010956:Plasmapheresis / Q000592:standards* / Q000706:statistics & numerical data; D012189:Retrospective Studies; D013116:Spinal Cord / Q000187:drug effects* / Q000276:immunology / Q000503:physiopathology; D016896:Treatment Outcome
chemical_list: D000305:Adrenal Cortex Hormones; D007166:Immunosuppressive Agents; D003520:Cyclophosphamide