Aspergillus oryzae peritonitis in CAPD: case report and review of the literature.
Fungal peritonitis is a rare, but serious, complication of continuous ambulatory peritoneal dialysis (CAPD). We report a case of peritonitis caused by Aspergillus oryzae in a man on CAPD therapy who was treated successfully with amphotericin B and caspofungin, followed by itraconazole and removal of the peritoneal catheter. A oryzae was identified by using sequence analysis of the ribosomal DNA genes. Of 10 reported cases since 2003, the mortality rate was 30%. Removal of the CAPD catheter and systemic antimycotic therapy are essential to achieve clinical cure in patients with fungal CAPD-related peritonitis.
Schwetz
Ines
I
Department of Pulmonology, Division of Infectious Diseases, Medical University of Graz, Austria.
Horina
Jörg
J
Buzina
Walter
W
Roob
Johannes
J
Olschewski
Horst
H
Krause
Robert
R
D000368:Aged; D000935:Antifungal Agents / Q000627:therapeutic use; D001228:Aspergillosis / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology; D001236:Aspergillus oryzae / Q000187:drug effects / Q000235:genetics / Q000254:growth & development / Q000302:isolation & purification*; D006801:Humans; D008297:Male; D010531:Peritoneal Dialysis, Continuous Ambulatory / Q000009:adverse effects*; D010538:Peritonitis / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology*
D000935:Antifungal Agents