Monofunctionalization of dendrimers with use of microwave-assisted 1,3-dipolar cycloadditions.
Monofunctionalized polyamide-based dendrimers containing either a terminal azide or alkyne moiety have been designed and synthesized via a convergent synthetic approach. The monofunctionalization allows for the single attachment of a functional moiety in quantitative yields by using 1,3-dipolar cycloadditions, thereby opening the possibility for targeted dendrimer functionalization.
Yoon
Kunsang
K
School of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, Georgia 30332-0400, USA. marcus.weck@chemistry.gatech.edu
Goyal
Poorva
P
Weck
Marcus
M
D050091:Dendrimers / Q000737:chemistry*; D008872:Microwaves; D015394:Molecular Structure; D009757:Nylons / Q000737:chemistry
D050091:Dendrimers; D009757:Nylons