title: [Oral ferric ammonium citrate solution in MRCP for diagnosing low-level obstructive jaundice].
abstract: OBJECTIVE
  To evaluate the value of oral ferric ammonium citrate solution as a gastrointestinal contrast agent in diagnosing low-level obstructive jaundice.
  
  
  METHODS
  Thirty-six patients who were suspected of low-level obstructive jaundice were performed with magnetic resonance cholangiopancreatography (MRCP) and conventional MRI before and after the administration of oral ferric ammonium citrate solution. The diagnostic accuracy for evaluating the site and the cause of obstruction was compared with other diagnostic modalities.
  
  
  RESULTS
  The image qualities of single-slice and multi-slice MRCP were improved markedly. The accuracy of MRCP for evaluating the site of obstruction was 97.22%, which was superior to US (P<0.05). There were no significant differences among the MRCP, CT, and ERCP.
  
  
  CONCLUSIONS
  Oral ferric ammonium citrate solution can significantly improve the image quality of MRCP. FAC-MRCP is a simple, safe, and noninvasive technique with excellent accuracy in the diagnosis of low-level obstructive jaundice.
authors.affiliation: Hepatobiliary & Enteric Surgery Research Center, Central South University, Changsha, China.
authors.forename: Pu
authors.initials: P
authors.lastname: Yang
authors.forename: Yang-de
authors.initials: YD
authors.lastname: Zhang
authors.forename: Nian-Feng
authors.initials: NF
authors.lastname: Li
authors.forename: Wen-Zheng
authors.initials: WZ
authors.lastname: Li
authors.forename: Gao-Feng
authors.initials: GF
authors.lastname: Zhou
mesh_terms: D000284:Administration, Oral; D000328:Adult; D000368:Aged; D049448:Cholangiopancreatography, Magnetic Resonance / Q000379:methods*; D042883:Choledocholithiasis / Q000175:diagnosis; D003287:Contrast Media; D005260:Female; D005290:Ferric Compounds / Q000008:administration & dosage; D006801:Humans; D041781:Jaundice, Obstructive / Q000175:diagnosis*; D008297:Male; D008875:Middle Aged; D000644:Quaternary Ammonium Compounds / Q000008:administration & dosage; D012680:Sensitivity and Specificity
chemical_list: D003287:Contrast Media; D005290:Ferric Compounds; D000644:Quaternary Ammonium Compounds; C013531:ferric ammonium citrate