title: [Amatoxin poisoning due to soup from personally picked deathcap mushrooms (Amanita phalloides)].
abstract: Two patients, a 54-year-old man and a 51-year-old woman, presented with abdominal pain, vomiting and diarrhoea; these symptoms developed 9 and 15 hours, respectively, after consumption of soup from mushrooms that they had picked themselves. As a result of these events, a third patient, a 55-year-old woman with diarrhoea who had also eaten the soup, also presented herself. The first patient recognised deathcap or death angel mushrooms (Amanita phalloides) on a photograph. All three patients were treated for amatoxin poisoning with a combination of high-dose penicillin G, silibinin and acetylcysteine intravenously. The poisoning was later confirmed by the results of urinalysis. The patients were discharged in good condition 8 days later.
authors.affiliation: Erasmus MC-Centrum, 's-Gravendijkwal 230, 3015 CE Rotterdam. s.jans@erasmusmc.nl
authors.forename: S A M
authors.initials: SA
authors.lastname: Ennecker-Jans
authors.forename: P L A
authors.initials: PL
authors.lastname: van Daele
authors.forename: M I
authors.initials: MI
authors.lastname: Blonk
authors.forename: D S E
authors.initials: DS
authors.lastname: Varin
authors.forename: J A M
authors.initials: JA
authors.lastname: van Laar
mesh_terms: D000111:Acetylcysteine / Q000627:therapeutic use; D000545:Amanita; D000546:Amanitins / Q000506:poisoning*; D000975:Antioxidants / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009145:Mushroom Poisoning / Q000175:diagnosis* / Q000188:drug therapy; D010400:Penicillin G / Q000627:therapeutic use; D000077385:Silybin; D012838:Silymarin / Q000627:therapeutic use; D016896:Treatment Outcome; D016482:Urinalysis
chemical_list: D000546:Amanitins; D000975:Antioxidants; D012838:Silymarin; D000077385:Silybin; C018207:amatoxin; D010400:Penicillin G; D000111:Acetylcysteine