title: Palladium-catalyzed conjugate reduction of enones into alpha,beta-dideuterioketones with hexamethyldisilane and deuterium oxide.
abstract: Conjugated enones are reduced by readily available Me(3)SiSiMe(3) and D(2)O in the presence of a catalytic amount of [PdCl(eta(3)-C(3)H(5))](2)-PPh(3) to give alpha,beta-dideuterioketones.
authors.affiliation: Department of Chemistry, Graduate School of Science, Kyoto University, Sakyo, Kyoto 606-8502, Japan.
authors.forename: Hidehito
authors.initials: H
authors.lastname: Otsuka
authors.forename: Eiji
authors.initials: E
authors.lastname: Shirakawa
authors.forename: Tamio
authors.initials: T
authors.lastname: Hayashi
mesh_terms: D002384:Catalysis; D017666:Deuterium Oxide / Q000737:chemistry*; D007553:Isotope Labeling; D007659:Ketones / Q000737:chemistry*; D010084:Oxidation-Reduction; D010165:Palladium / Q000737:chemistry*; D012821:Silanes / Q000737:chemistry*
chemical_list: D007659:Ketones; D012821:Silanes; C520781:hexamethyldisilane; D010165:Palladium; D017666:Deuterium Oxide