title: Selection of local anesthetics in dentistry: clinical impression versus scientific assessment.
abstract: Since its introduction to in the United States about six years ago, 4% articaine with 1:200,000 epinephrine has been used by dentists as a local anesthetic agent. This article reviews three claims that have been advanced regarding articaine: high diffusibility, reduced incidence of failure in block injections, and effectiveness in achieving anesthesia when used in cases involving irreversible pulpitis.
authors.affiliation: Department of Restorative Dentistry and Biomaterials University of Texas Dental Branch-Houston, USA. Arthur.h.jeske@uth.tmc.edu
authors.forename: Arthur J
authors.initials: AJ
authors.lastname: Jeske
authors.forename: Patricia L
authors.initials: PL
authors.lastname: Blanton
mesh_terms: D000766:Anesthesia, Dental / Q000379:methods*; D000779:Anesthetics, Local / Q000493:pharmacokinetics / Q000627:therapeutic use*; D002355:Carticaine / Q000493:pharmacokinetics / Q000627:therapeutic use*; D006801:Humans; D014098:Toothache / Q000188:drug therapy
chemical_list: D000779:Anesthetics, Local; D002355:Carticaine