title: Interleukin-12: a master regulator.
abstract: Early resistance to pathogens requires a swift response from NK cells. In 1989, Giorgio Trinchieri identified an NK growth factor and activator, later called interleukin-12 (IL-12). This discovery helped reveal the regulatory link between innate and adaptive immunity.
authors.forename: Hema
authors.initials: H
authors.lastname: Bashyam
mesh_terms: D056704:Adaptive Immunity; D000818:Animals; D006801:Humans; D007113:Immunity, Innate; D018664:Interleukin-12 / Q000502:physiology*; D007694:Killer Cells, Natural / Q000166:cytology* / Q000276:immunology; D051379:Mice; D015398:Signal Transduction
chemical_list: D018664:Interleukin-12