Evaluation of a new turbidimetric assay for von Willebrand factor activity useful in the general screening of von Willebrand disease.
We evaluated a new assay (HemosIL VWF Activity on ACL-Futura) in the screening of VWD. Samples from healthy donors and previously diagnosed VWD patients were blindly analyzed by this new activity assay and standard VWF:RCo. Results agreed and both assays showed a similar sensitivity for the screening of VWD.
Piñol
Montse
M
Sales
Miquel
M
Costa
Marta
M
Tosetto
Alberto
A
Canciani
Maria Teresa
MT
Federici
Augusto B
AB
D000911:Antibodies, Monoclonal / Q000276:immunology; D001331:Automation; D006801:Humans; D007841:Latex Fixation Tests; D009391:Nephelometry and Turbidimetry / Q000379:methods*; D019038:Platelet Glycoprotein GPIb-IX Complex / Q000378:metabolism; D012680:Sensitivity and Specificity; D016037:Single-Blind Method; D014842:von Willebrand Diseases / Q000097:blood* / Q000145:classification; D014841:von Willebrand Factor / Q000032:analysis*
D000911:Antibodies, Monoclonal; D019038:Platelet Glycoprotein GPIb-IX Complex; D014841:von Willebrand Factor