title: Coronary artery disease cannot be reliably evaluated by 16-slice multidetector spiral computed tomography.
abstract: OBJECTIVE
  Angiography by selective catheterization is the standard method for coronary artery imaging but carries a risk of rare, but serious complications. We investigated whether 16-slice multidetector spiral computed tomography (MDCT) could substitute for selective angiography for evaluation of coronary artery disease in surgically revascularized patients.
  
  
  METHODS
  In a setting closely resembling routine clinical practice, 45 patients who had been operated with coronary artery bypass grafting 508-1135 (mean 811) days before were examined with MDCT and conventional selective angiography on the same day. The interpreters were blinded to the results of the parallel imaging modality.
  
  
  RESULTS
  Significant pathology (stenosis >/=50% or occlusion) in the larger coronary artery segments was detected by MDCT with a sensitivity of 70-98% (mean 87%) and a specificity of 0-37% (mean 21%). MDCT failed to identify three of ten left main stem stenoses.
  
  
  CONCLUSIONS
  Sixteen-slice MDCT cannot routinely replace selective angiography for evaluation of coronary artery disease.
authors.affiliation: Department of Cardiothoracic and Vascular Surgery, University Hospital North Norway, Tromsø, Norway. kristian.bartnes@unn.no
authors.forename: Kristian
authors.initials: K
authors.lastname: Bartnes
authors.forename: Trude
authors.initials: T
authors.lastname: Sildnes
authors.forename: Amjid
authors.initials: A
authors.lastname: Iqbal
authors.forename: Oystein
authors.initials: O
authors.lastname: Dahl-Eriksen
authors.forename: Thor
authors.initials: T
authors.lastname: Trovik
authors.forename: Terje Kristian
authors.initials: TK
authors.lastname: Steigen
authors.forename: Rica
authors.initials: R
authors.lastname: Mortensen
authors.forename: Jan Torbjørn
authors.initials: JT
authors.lastname: Mannsverk
authors.forename: Dag Glen
authors.initials: DG
authors.lastname: Sørlie
authors.forename: Truls
authors.initials: T
authors.lastname: Myrmel
mesh_terms: D017023:Coronary Angiography / Q000379:methods*; D001026:Coronary Artery Bypass; D023921:Coronary Stenosis / Q000000981:diagnostic imaging* / Q000503:physiopathology / Q000601:surgery; D005240:Feasibility Studies; D006801:Humans; D011237:Predictive Value of Tests; D017534:Radial Artery / Q000637:transplantation; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D036542:Tomography, Spiral Computed; D016896:Treatment Outcome; D014654:Vascular Patency