title: [Interaction of chaotropically modified immunoglobulins with protein and glicolipid antigens].
abstract: The features of interaction of native and chaotropically modified immunoglobulins with proteins (ovalbumin) and glicolipids (lipopolysaccharides, LPS) enterobacteria Escherichia coli K235, Salmonella minnesota and Salmonella enteritidis have been investigated. It has been established, that after processing of native antibodies with 3.5 M KSCN their ability to contact to the specified antigenes repeatedly grows. Besides the intensity of interaction of modified immunoglobulins with the mentioned above antigenes was various, that is determined by the presence of structural distinctions between antigen determinants of proteins and glycolipid antigens, and also between O-polysaccharide chains of LPS in different species of enterobacteria.
authors.forename: A I
authors.initials: AI
authors.lastname: Gordienko
authors.forename: N V
authors.initials: NV
authors.lastname: Khimich
mesh_terms: D000915:Antibody Affinity; D000942:Antigens, Bacterial / Q000276:immunology*; D001426:Bacterial Proteins / Q000276:immunology*; D001666:Binding Sites, Antibody; D004591:Electrophoresis, Polyacrylamide Gel; D004755:Enterobacteriaceae / Q000276:immunology*; D004926:Escherichia coli / Q000276:immunology; D006801:Humans; D007124:Immunoenzyme Techniques; D007136:Immunoglobulins / Q000097:blood / Q000276:immunology*; D007163:Immunosorbent Techniques; D008070:Lipopolysaccharides / Q000276:immunology*; D010047:Ovalbumin / Q000276:immunology; D010504:Periodic Acid / Q000494:pharmacology; D012477:Salmonella enteritidis / Q000276:immunology; D013861:Thiocyanates / Q000494:pharmacology
chemical_list: D000942:Antigens, Bacterial; D001426:Bacterial Proteins; D007136:Immunoglobulins; D008070:Lipopolysaccharides; D013861:Thiocyanates; D010504:Periodic Acid; D010047:Ovalbumin; C009288:metaperiodate; C009941:potassium thiocyanate