Pneumocystis pneumonia in HIV-positive adults, Malawi.
In a prospective study of 660 HIV-positive Malawian adults, we diagnosed Pneumocystis jirovecii pneumonia (PcP) using clinical features, induced sputum for immunofluorescent staining, real-time PCR, and posttreatment follow-up. PcP incidence was highest in patients with the lowest CD4 counts, but PcP is uncommon compared with incidences of pulmonary tuberculosis and bacterial pneumonia.
van Oosterhout
Joep J G
JJ
University of Malawi College of Medicine, Blantyre, Malawi.
Laufer
Miriam K
MK
Perez
M Arantza
MA
Graham
Stephen M
SM
Chimbiya
Nelson
N
Thesing
Phillip C
PC
Alvarez-Martinez
Miriam J
MJ
Wilson
Paul E
PE
Chagomerana
Maganizo
M
Zijlstra
Eduard E
EE
Taylor
Terrie E
TE
Plowe
Christopher V
CV
Meshnick
Steven R
SR
D017088:AIDS-Related Opportunistic Infections / Q000175:diagnosis / Q000453:epidemiology; D000293:Adolescent; D000328:Adult; D005260:Female; D015658:HIV Infections / Q000150:complications* / Q000453:epidemiology; D006801:Humans; D015994:Incidence; D008295:Malawi / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D011020:Pneumonia, Pneumocystis / Q000150:complications* / Q000453:epidemiology*