ChromatinDB: a database of genome-wide histone modification patterns for Saccharomyces cerevisiae.
Covalent modifications to histone proteins play a critical role in regulating gene transcription. Previous studies have used chromatin immunoprecipitation (ChIP) based microarray assays to profile genomic regions that are enriched or depleted for a particular histone modification. Such studies have been conducted extensively in the yeast Saccharomyces cerevisiae, but currently no comprehensive data repositories or analysis tools are available for these data sets. For this reason, we have developed the ChromatinDB database, which contains genome-wide ChIP data for 22 different histones or histone modifications in S. cerevisiae. ChromatinDB provides novel tools to facilitate the visualization and statistical analysis of chromatin features for user-selected gene sets.


BACKGROUND
http://www.bioinformatics2.wsu.edu/ChromatinDB.


BACKGROUND
Supplementary data are available at Bioinformatics online.
O'Connor
Timothy R
TR
School of Molecular Biosciences and Center for Reproductive Biology, Washington State University, Pullman, WA, USA.
Wyrick
John J
JJ
D002843:Chromatin / Q000737:chemistry*; D047369:Chromatin Immunoprecipitation; D019295:Computational Biology / Q000379:methods*; D003196:Computer Graphics; D016208:Databases, Factual; D016681:Genome, Fungal; D051548:Histone Acetyltransferases / Q000378:metabolism; D006657:Histones / Q000378:metabolism*; D008957:Models, Genetic; D015233:Models, Statistical; D016366:Open Reading Frames; D011401:Promoter Regions, Genetic; D012441:Saccharomyces cerevisiae / Q000235:genetics* / Q000378:metabolism*; D029701:Saccharomyces cerevisiae Proteins / Q000378:metabolism; D000099224:p300-CBP-Associated Factor
D002843:Chromatin; D051548:Histone Acetyltransferases; D006657:Histones; D029701:Saccharomyces cerevisiae Proteins; C501392:GCN5 protein, S cerevisiae; D000099224:p300-CBP-Associated Factor