Neuronal vacuolation in an adult ferret.
The brain of a ferret showing abnormal neurologic signs was evaluated by histopathologic, histochemical, immunohistochemical, and ultrastructural examinations. Extensive neuronal vacuolation was observed. Since the brain was negative for protease-resistant protein prion (PrP'"), it was concluded that this was not a case of transmissible spongiform encephalopathy.
Hamir
Amir N
AN
National Animal Disease Center, ARS, USDA, 2300 Dayton Road, P.O. Box 70, Ames, Iowa 50010, USA. ahamir@nadc.ars.usda.gov
Miller
Janice M
JM
Yaeger
Michael J
MJ
D000818:Animals; D001927:Brain Diseases / Q000175:diagnosis / Q000473:pathology / Q000662:veterinary*; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D005260:Female; D005289:Ferrets; D007150:Immunohistochemistry / Q000662:veterinary; D009474:Neurons / Q000473:pathology* / Q000648:ultrastructure; D014617:Vacuoles / Q000473:pathology* / Q000648:ultrastructure