title: Geographical distribution and accumulation features of PBDEs in human breast milk from Indonesia.
abstract: The present study reports concentrations of polybrominated diphenyl ethers (PBDEs) and organochlorines (OCs) in human breast milk from Indonesia covering urban, suburban and rural areas. PBDEs were detected in all the samples of the present study with total concentrations ranging from 0.49 to 13 ng/g lipid wt. Geographical distribution showed that concentrations of PBDEs were relatively uniform (p>0.05) and the levels were in the same order as those in Japan and some European countries, but were one or two order lower than North America. When compared to OCs, the level of total PBDEs was lower. The congener pattern was in accordance with other studies on human matrices, in which BDE-47 was the most abundant congener. Variations of PBDE congeners in human breast milk were further discussed to elucidate the potential exposure source(s) and pathways.
authors.affiliation: Center for Marine Environmental Studies (CMES), Ehime University, Bunkyo-cho 2-5, Matsuyama 790-8577, Japan.
authors.forename: Agus
authors.initials: A
authors.lastname: Sudaryanto
authors.forename: Natsuko
authors.initials: N
authors.lastname: Kajiwara
authors.forename: Shin
authors.initials: S
authors.lastname: Takahashi
authors.lastname: Muawanah
authors.forename: Shinsuke
authors.initials: S
authors.lastname: Tanabe
mesh_terms: D000328:Adult; D004781:Environmental Exposure; D004784:Environmental Monitoring / Q000379:methods; D004785:Environmental Pollutants / Q000032:analysis*; D005260:Female; D005411:Flame Retardants / Q000032:analysis*; D055768:Halogenated Diphenyl Ethers; D006801:Humans; D006843:Hydrocarbons, Chlorinated / Q000032:analysis; D007214:Indonesia; D008895:Milk, Human / Q000737:chemistry*; D010647:Phenyl Ethers / Q000032:analysis*; D011075:Polybrominated Biphenyls / Q000032:analysis*; D011247:Pregnancy; D018570:Risk Assessment / Q000379:methods
chemical_list: D004785:Environmental Pollutants; D005411:Flame Retardants; D055768:Halogenated Diphenyl Ethers; D006843:Hydrocarbons, Chlorinated; D010647:Phenyl Ethers; D011075:Polybrominated Biphenyls; C517828:hexabrominated diphenyl ether 153; C511295:2,2',4,4'-tetrabromodiphenyl ether; C086401:pentabromodiphenyl ether; C010902:decabromobiphenyl ether