title: Recombinant human activated protein C sentenced to the death of a thousand cuts?
authors.forename: James M
authors.initials: JM
authors.lastname: O'Brien
mesh_terms: D018806:APACHE; D000890:Anti-Infective Agents / Q000009:adverse effects / Q000627:therapeutic use*; D006801:Humans; D011486:Protein C / Q000009:adverse effects / Q000627:therapeutic use*; D011994:Recombinant Proteins / Q000009:adverse effects / Q000627:therapeutic use; D012107:Research Design; D018805:Sepsis / Q000188:drug therapy* / Q000401:mortality; D016019:Survival Analysis
chemical_list: D000890:Anti-Infective Agents; D011486:Protein C; D011994:Recombinant Proteins; C421124:drotrecogin alfa activated