Treatment of chronic fatigue and orthostatic intolerance with propranolol.
We describe the effect of propranolol in an adolescent with chronic fatigue syndrome and orthostatic intolerance. Our observations suggest that the head-up tilt-test and beta-blocker treatment might be considered in patients with chronic fatigue syndrome and that enhanced sympathetic nervous activity might be part of the underlying pathophysiology.
Wyller
Vegard Bruun
VB
Department of Pediatrics, Rikshospitalet-Radiumhospitalet Medical Centre, Oslo, Norway. brwylle@online.no
Thaulow
Erik
E
Amlie
Jan P
JP
D000293:Adolescent; D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use*; D015673:Fatigue Syndrome, Chronic / Q000188:drug therapy* / Q000503:physiopathology; D006801:Humans; D007024:Hypotension, Orthostatic / Q000188:drug therapy* / Q000503:physiopathology; D008297:Male; D011433:Propranolol / Q000627:therapeutic use*
D000319:Adrenergic beta-Antagonists; D011433:Propranolol