[A clinicopathological analysis of liver retransplantation in 22 cases].
OBJECTIVE
To analyze the clinical and pathological features of patients with liver retransplantation.


METHODS
The clinical and pathological data of 22 patients who had liver retransplantation at our center from October 2003 to June 2006 were retrospectively analyzed.


RESULTS
Among the 523 patients who underwent liver transplantation, 22 (4.4%) had liver retransplantation. The causes of liver retransplantation were biliary tract complications (13/22), hepatic artery thrombosis (3/22), recurrence of hepatocellular carcinoma (5/22) and nonfunctional primary graft (1/22). The pathological changes in the livers of patients with biliary complications were intrahepatic cholestasis, primary bile duct hyperplasia and neutrophil infiltrations.


CONCLUSIONS
Biliary tract complications are the main cause of liver retransplantation. Differential diagnosis of various complications through early liver puncture biopsy and imaging examination will contribute to guide clinical treatment and may help in avoiding liver retransplantation.
Shao
Chun-kui
CK
Department of Pathology, Organ Transplantation Center, Third Affiliated Hospital, Sun Yat-sen University, Guangzhou 510630, China. shaock2001@yahoo.com
Zhou
Jing
J
Feng
Zhi-ying
ZY
Chen
Gui-hua
GH
D000328:Adult; D000368:Aged; D005260:Female; D006085:Graft Survival; D006801:Humans; D008099:Liver / Q000473:pathology*; D016031:Liver Transplantation; D008297:Male; D008875:Middle Aged; D012086:Reoperation; D012189:Retrospective Studies; D019737:Transplants