title: High levels of CA125 (over 1,000 IU/ml) in patients with gynecologic disease and no malignant conditions: three cases and literature review.
abstract: OBJECTIVE
  To report the very high serum levels of CA125 in patients with benign gynecologic disease which manifests as pelvic mass.
  
  
  METHODS
  Clinical data of three cases with high levels of CA125 over 1,000 IU/ml and benign gynecologic conditions were gathered. in Vali-Asr hospital.
  
  
  RESULTS
  Three patients were scheduled for laparatomy as ovarian cancer and leiomyosarcoma. Histologic results after laparatomy showed uterine myoma in two patients and endometrioma in a third patient.
  
  
  CONCLUSIONS
  High levels of CA125 over 1,000 IU/ml, may be showed in other gynecologic conditions with no malignancy. So, other clinical and imaging data could be helpful for differential diagnosis of these patients.
authors.affiliation: Gynecologic Oncology Department, Vali-e-Asr Hospital, Tehran University of Medical Sciences, Imam Khomeini Hospital Complex, Tehran 14194, Iran.
authors.forename: Fatemeh
authors.initials: F
authors.lastname: Ghaemmaghami
authors.forename: Mojgan
authors.initials: M
authors.lastname: Karimi Zarchi
authors.forename: Bahareh
authors.initials: B
authors.lastname: Hamedi
mesh_terms: D000328:Adult; D018394:CA-125 Antigen / Q000097:blood*; D003937:Diagnosis, Differential; D016889:Endometrial Neoplasms / Q000097:blood / Q000175:diagnosis* / Q000601:surgery; D004715:Endometriosis / Q000097:blood / Q000175:diagnosis* / Q000601:surgery; D005260:Female; D006801:Humans; D007889:Leiomyoma / Q000097:blood / Q000175:diagnosis* / Q000601:surgery; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000175:diagnosis; D014594:Uterine Neoplasms / Q000097:blood / Q000175:diagnosis* / Q000601:surgery
chemical_list: D018394:CA-125 Antigen