Dermoscopic findings in Laugier-Hunziker syndrome.
BACKGROUND
Laugier-Hunziker syndrome (LHS) is a rare, acquired mucocutaneous hyperpigmentation often associated with longitudinal melanonychia. The clinical behavior of mucocutaneous pigmented lesions ranges from benign to highly malignant. Therefore, in most cases, the clinical diagnosis should be confirmed by further diagnostic methods. Dermoscopy is a noninvasive technique that has been used to make more accurate diagnoses of pigmented skin lesions. Nevertheless, to our knowledge, the dermoscopic features of the pigmented lesions in LHS have not been described previously. Herein, we report a case of LHS together with its dermoscopic features.


METHODS
The clinical examination revealed macular hyperpigmentation on the oral and genital mucosa, conjunctiva, and palmoplantar region together with longitudinal melanonychia. Dermoscopic examination of mucosal lesions on the patient's lips and vulva revealed a parallel pattern. Longitudinal homogeneous pigmentation was observed on the toenails. The pigmented macules on the palms and the sole showed a parallel furrow pattern. A skin biopsy sample taken from the labial lesion was compatible with a diagnosis of mucosal melanosis.


CONCLUSIONS
By means of this case report, the dermoscopic features of the pigmented lesions in LHS are described for the first time, which facilitates diagnosis with a noninvasive technique. Future reports highlighting the dermoscopic features of this syndrome may simplify the diagnosis of LHS, which is thought to be underdiagnosed.
Gencoglan
Gulsum
G
Department of Dermatology, Ege University, Izmir, Turkey.
Gerceker-Turk
Bengu
B
Kilinc-Karaarslan
Isil
I
Akalin
Taner
T
Ozdemir
Fezal
F
D000328:Adult; D046169:Dermoscopy; D005260:Female; D006801:Humans; D017495:Hyperpigmentation / Q000473:pathology*; D009061:Mouth Mucosa / Q000473:pathology; D009260:Nail Diseases / Q000473:pathology*; D013577:Syndrome; D014844:Vulva / Q000473:pathology