title: [Infection of a total knee prosthesis with Brucella spp].
abstract: Brucellosis, an "anthropophitic" disease of worldwide distribution can involve several organs and tissues but the osteoarticular disease is the most common complication. It can occur as sacroiliitis, bursitis, tenosynovitis or osteomyelitis. Prosthetic joint infection is a serious complication of total joint arthroplasty, with coagulase negative staphylococci and Staphylococcus aureus accounting for 50% of cases. Treatment of prosthetic infections remains complex. Prosthetic infections caused by Brucella spp are rarely described in the literature. We report a patient with a prosthetic joint infection due to Brucella spp, documented by a polymerase chain reaction. The patient has been cured after two-stage exchange of the prosthesis and long-term antimicrobial therapy.
authors.affiliation: Service d'orthopédie et de traumatologie de l'appareil moteur, Hôpital du Chablais, 1870 Monthey. francesco.marbach@fhv.ch
authors.forename: F
authors.initials: F
authors.lastname: Marbach
authors.forename: L
authors.initials: L
authors.lastname: Saiah
authors.forename: J F
authors.initials: JF
authors.lastname: Fischer
authors.forename: J
authors.initials: J
authors.lastname: Huismans
authors.forename: A
authors.initials: A
authors.lastname: Cometta
mesh_terms: D000368:Aged; D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D019645:Arthroplasty, Replacement, Knee / Q000009:adverse effects*; D002002:Brucella / Q000302:isolation & purification*; D002006:Brucellosis / Q000188:drug therapy / Q000382:microbiology* / Q000601:surgery; D004318:Doxycycline / Q000008:administration & dosage; D004334:Drug Administration Schedule; D004359:Drug Therapy, Combination; D006801:Humans; D008297:Male; D016459:Prosthesis-Related Infections / Q000188:drug therapy / Q000382:microbiology* / Q000601:surgery; D012086:Reoperation; D012293:Rifampin / Q000008:administration & dosage; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents; D004318:Doxycycline; D012293:Rifampin