Fawcettimine-related alkaloids from Lycopodium serratum.
Five new Lycopodium alkaloids (1-5) having the fawcettimine skeleton were isolated from Lycopodium serratum. The structures of the alkaloids were elucidated on the basis of spectroscopic analysis. Some alkaloids isolated in this and previous studies (1, 2, 5, and 10) were assayed for acetylcholine esterase (AChE) inhibitory activity.
Katakawa
Kazuaki
K
Graduate School of Pharmaceutical Sciences, Chiba University, 1-33 Yayoi-cho, Inage-ku, Chiba 263-8522, Japan.
Nozoe
Akiko
A
Kogure
Noriyuki
N
Kitajima
Mariko
M
Hosokawa
Masakiyo
M
Takayama
Hiromitsu
H
D000470:Alkaloids / Q000737:chemistry* / Q000302:isolation & purification* / Q000494:pharmacology; D002800:Cholinesterase Inhibitors / Q000737:chemistry* / Q000302:isolation & purification* / Q000494:pharmacology; D006576:Heterocyclic Compounds, 4 or More Rings / Q000737:chemistry* / Q000302:isolation & purification* / Q000494:pharmacology; D007564:Japan; D032502:Lycopodium / Q000737:chemistry*; D015394:Molecular Structure; D010946:Plants, Medicinal / Q000737:chemistry*
D000470:Alkaloids; D002800:Cholinesterase Inhibitors; D006576:Heterocyclic Compounds, 4 or More Rings