title: Detection of the virulent Marek's disease virus genome from feather tips of wild geese in Japan and the Far East region of Russia.
abstract: Marek's disease (MD) virus (MDV) is known to cause malignant lymphomas in chickens. In 2001, we first reported an MD case in a white-fronted goose (Anser albifrons) in Japan. Therefore, the prevalence of MDV in the wild geese was surveyed by nested PCR using feather-tip samples in Japan and the Far East region of Russia, breeding habitats of geese migrating to Japan. MDV was detected in about 30% of analyzed white-fronted geese. Furthermore, by nucleotide sequence analysis, we confirmed that this MDV shows high homology to very virulent MDV, suggesting that highly virulent MDV is widespread in white-fronted geese migrating between Japan and Far East region of Russia.
authors.affiliation: Department of Disease Control, Graduate School of Veterinary Medicine, Hokkaido University, Sapporo, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Murata
authors.forename: K-S
authors.initials: KS
authors.lastname: Chang
authors.forename: Y
authors.initials: Y
authors.lastname: Yamamoto
authors.forename: T
authors.initials: T
authors.lastname: Okada
authors.forename: S-I
authors.initials: SI
authors.lastname: Lee
authors.forename: S
authors.initials: S
authors.lastname: Konnai
authors.forename: M
authors.initials: M
authors.lastname: Onuma
authors.forename: Y
authors.initials: Y
authors.lastname: Osa
authors.forename: M
authors.initials: M
authors.lastname: Asakawa
authors.forename: K
authors.initials: K
authors.lastname: Ohashi
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D000835:Animals, Wild / Q000821:virology*; D001715:Bird Diseases / Q000453:epidemiology* / Q000821:virology; D005241:Feathers / Q000821:virology*; D005777:Geese / Q000821:virology*; D016679:Genome, Viral; D008381:Herpesvirus 2, Gallid / Q000235:genetics / Q000302:isolation & purification* / Q000472:pathogenicity; D007564:Japan / Q000453:epidemiology; D008380:Marek Disease / Q000453:epidemiology* / Q000821:virology; D008969:Molecular Sequence Data; D009856:Oncogene Proteins, Viral / Q000737:chemistry / Q000235:genetics; D015995:Prevalence; D012426:Russia / Q000453:epidemiology; D014774:Virulence
chemical_list: C100369:Eco-Q protein, Gallid herpesvirus 2; D009856:Oncogene Proteins, Viral