title: Joint-specific hand symptoms and self-reported and performance-based functional status in African Americans and Caucasians: The Johnston County Osteoarthritis Project.
abstract: OBJECTIVE
  To assess associations between joint-specific hand symptoms and self-reported and performance-based functional status.
  
  
  METHODS
  Participants were from the population-based Johnston County Osteoarthritis Project. Symptoms in the distal interphalangeal (DIP), proximal interphalangeal (PIP), first carpometacarpal (CMC), and metacarpophalangeal (MCP) joints were assessed on a 30-joint diagram of both hands. Self-reported function was assessed by Health Assessment Questionnaire (HAQ) and performance-based function by timed repeated chair stands and 8-foot walk time. Separate multiple logistic regression models examined associations between symptoms in specific hand joint groups, symptoms in >/=2 hand joint groups and number of symptomatic hand joints, and functional status measures, controlling for age, race/ethnicity, sex, body mass index, radiographic knee and hip OA, knee and hip symptoms and depressive symptoms.
  
  
  RESULTS
  Those with symptomatic hand joint groups were more likely than those without these complaints to report more difficulty and require longer times for performance measures. Those with 2 or more symptomatic hand joint groups were more likely to have higher HAQ scores (OR = 1.97 (1.53 to 2.53)) and require more time to complete 5 chair stands (OR = 1.98 (1.23 to 3.18)) and the 8 foot walk test (OR = 1.49 (1.12 to 1.99)).
  
  
  CONCLUSIONS
  Joint-specific hand symptoms are associated with difficulty performing upper- or lower-extremity tasks, independent of knee and hip OA and symptoms, suggesting that studies examining functional status in OA should not ignore symptomatic joints beyond the joint site of interest, even when functional measures appear to be specific for the joint site under study.
authors.affiliation: Thurston Arthritis Research Center, University of North Carolina at Chapel Hill School of Medicine, Division of Rheumatology, Allergy, and Immunology, 3300 Thurston Building, CB#7280, Chapel Hill, NC 27599-7280, USA.
authors.forename: A L
authors.initials: AL
authors.lastname: Elliott
authors.forename: V B
authors.initials: VB
authors.lastname: Kraus
authors.forename: F
authors.initials: F
authors.lastname: Fang
authors.forename: J B
authors.initials: JB
authors.lastname: Renner
authors.forename: T A
authors.initials: TA
authors.lastname: Schwartz
authors.forename: A
authors.initials: A
authors.lastname: Salazar
authors.forename: T
authors.initials: T
authors.lastname: Huguenin
authors.forename: M C
authors.initials: MC
authors.lastname: Hochberg
authors.forename: C G
authors.initials: CG
authors.lastname: Helmick
authors.forename: J M
authors.initials: JM
authors.lastname: Jordan
mesh_terms: D000203:Activities of Daily Living; D000328:Adult; D001741:Black or African American; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D000704:Analysis of Variance; D001175:Arthrography; D005260:Female; D050823:Hand Joints / Q000503:physiopathology*; D006621:Hip Joint / Q000503:physiopathology; D006801:Humans; D007719:Knee Joint / Q000503:physiopathology; D016014:Linear Models; D008297:Male; D008875:Middle Aged; D010003:Osteoarthritis / Q000000981:diagnostic imaging / Q000208:ethnology / Q000503:physiopathology*; D015207:Osteoarthritis, Hip / Q000000981:diagnostic imaging / Q000208:ethnology / Q000503:physiopathology; D020370:Osteoarthritis, Knee / Q000000981:diagnostic imaging / Q000208:ethnology / Q000503:physiopathology; D016059:Range of Motion, Articular; D012737:Sex Factors; D044465:White People