Adipose-derived stem cells for regenerative medicine.
The emerging field of regenerative medicine will require a reliable source of stem cells in addition to biomaterial scaffolds and cytokine growth factors. Adipose tissue represents an abundant and accessible source of adult stem cells with the ability to differentiate along multiple lineage pathways. The isolation, characterization, and preclinical and clinical application of adipose-derived stem cells (ASCs) are reviewed in this article.
Gimble
Jeffrey M
JM
Stem Cell Biology Laboratory and Clinical Nutrition Research Unit, Pennington Biomedical Research Center, Louisiana State University System, Baton Rouge, LA 70808, USA. gimblejm@pbrc.edu
Katz
Adam J
AJ
Bunnell
Bruce A
BA
D050156:Adipogenesis; D000273:Adipose Tissue / Q000166:cytology*; D053687:Adult Stem Cells / Q000166:cytology*; D002454:Cell Differentiation; D019070:Cell Lineage; D049109:Cell Proliferation; D002469:Cell Separation / Q000379:methods; D006801:Humans; D016130:Immunophenotyping; D008067:Lipoma / Q000473:pathology; D008080:Liposarcoma / Q000473:pathology; D009765:Obesity / Q000473:pathology; D020543:Proteome; D009626:Terminology as Topic; D023822:Tissue Engineering
D020543:Proteome