title: Peroxisome proliferator-activated receptor gamma coactivator-1 (PGC-1) regulatory cascade in cardiac physiology and disease.
authors.affiliation: Center for Human Nutrition, Washington University School of Medicine, St. Louis, MO 63110, USA.
authors.forename: Brian N
authors.initials: BN
authors.lastname: Finck
authors.forename: Daniel P
authors.initials: DP
authors.lastname: Kelly
mesh_terms: D002001:Adipose Tissue, Brown / Q000378:metabolism; D000818:Animals; D006332:Cardiomegaly / Q000378:metabolism / Q000503:physiopathology; D009202:Cardiomyopathies / Q000378:metabolism / Q000503:physiopathology*; D004272:DNA, Mitochondrial / Q000235:genetics; D004734:Energy Metabolism / Q000502:physiology; D005227:Fatty Acids / Q000378:metabolism; D005786:Gene Expression Regulation / Q000502:physiology; D005947:Glucose / Q000378:metabolism; D006333:Heart Failure / Q000378:metabolism / Q000503:physiopathology; D006360:Heat-Shock Proteins / Q000502:physiology*; D006801:Humans; D051379:Mice; D018345:Mice, Knockout; D008929:Mitochondria, Heart / Q000378:metabolism / Q000502:physiology*; D023421:Models, Animal; D008954:Models, Biological; D051266:Nuclear Respiratory Factor 1 / Q000502:physiology; D010084:Oxidation-Reduction; D000071248:Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; D047492:Peroxisome Proliferator-Activated Receptors / Q000502:physiology; D011960:Receptors, Estrogen / Q000502:physiology; D015534:Trans-Activators / Q000502:physiology*; D014157:Transcription Factors / Q000502:physiology*; D014158:Transcription, Genetic; D000097983:ERRalpha Estrogen-Related Receptor
chemical_list: D004272:DNA, Mitochondrial; D005227:Fatty Acids; D005947:Glucose; D006360:Heat-Shock Proteins; D051266:Nuclear Respiratory Factor 1; D000071248:Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; D047492:Peroxisome Proliferator-Activated Receptors; D011960:Receptors, Estrogen; D015534:Trans-Activators; D014157:Transcription Factors; D000097983:ERRalpha Estrogen-Related Receptor; C495633:NRF1 protein, human; C495634:Nrf1 protein, mouse; C486497:PPARGC1A protein, human; C485290:Ppargc1a protein, mouse