title: A computational model of activities performance decrease in Alzheimer's disease.
abstract: This article presents a computational model and a simulation of the decrease of performance in daily living activities due to Alzheimer's disease. The framework offered by the cognitive architecture ACT-R is used to develop the model. Typical errors committed in performing tasks by Alzheimer patients are modelled thanks to different parametrisable memory mechanisms of ACT-R and the disease evolution is represented by the increase of errors in the execution of the task. The model is applied to a cooking activity. Simulation of 100 subjects shows results similar to those realised in a standardized assessment with human subjects. We conclude on the need to introduce executive mechanisms in the modelling of behaviours associated to people with cognitive deficits.
authors.affiliation: TIMC-IMAG UMR CNRS 5525 Laboratory, Grenoble, France. Audrey.Serna@imag.fr
authors.forename: Audrey
authors.initials: A
authors.lastname: Serna
authors.forename: Hélène
authors.initials: H
authors.lastname: Pigot
authors.forename: Vincent
authors.initials: V
authors.lastname: Rialle
mesh_terms: D000203:Activities of Daily Living; D000544:Alzheimer Disease / Q000503:physiopathology; D003071:Cognition; D003198:Computer Simulation; D006801:Humans; D013647:Task Performance and Analysis