[Intestinal endotoxin in the pathogenesis of ocular inflammatory diseases and the antiendoxin constituent of its treatment].
Blood was studied in 119 patients with ocular inflammatory lesions: endophthalmitis (n = 10), iridocyclitis of viral (n = 47) and unknown (n = 62) genesis, by using the procedures developed by the authors to determine the integral values of the concentration of endotoxin in systemic blood flow and the activity of antiendotoxin immunity. Intestinal endotoxin aggression was found to be involved in the pathogenesis of ocular inflammatory diseases. The use of drugs and procedures, which could diminish the entry of intestinal endotoxin into the blood stream and intensify the processes of its binding and release from systemic blood circulation, substantially enhanced the efficiency of a therapeutic process.
Vyshegurov
Ia Kh
IaKh
Anikhovskaia
I A
IA
Batmanov
Iu E
IuE
Iakovlev
M Iu
MIu
D000328:Adult; D000368:Aged; D009877:Endophthalmitis / Q000097:blood / Q000209:etiology / Q000628:therapy; D004731:Endotoxins / Q000097:blood* / Q000633:toxicity; D015817:Eye Infections / Q000097:blood / Q000209:etiology* / Q000628:therapy*; D005839:Gentamicins / Q000627:therapeutic use; D006801:Humans; D007410:Intestinal Diseases / Q000382:microbiology; D015863:Iridocyclitis / Q000097:blood / Q000209:etiology / Q000628:therapy; D008070:Lipopolysaccharides / Q000097:blood; D008165:Luminol / Q000031:analogs & derivatives; D008875:Middle Aged; D010793:Phthalazines / Q000627:therapeutic use; D016896:Treatment Outcome; D014605:Uveitis / Q000097:blood / Q000209:etiology* / Q000628:therapy
D004731:Endotoxins; D005839:Gentamicins; D008070:Lipopolysaccharides; D010793:Phthalazines; D008165:Luminol; C511308:sodium luminolate