Quantitative magnetic resonance imaging of articular cartilage in osteoarthritis.
Magnetic resonance imaging of articular cartilage has recently been recognized as a tool for the characterization of cartilage morphology, biochemistry and function. In this paper advancements in cartilage imaging, computation of cartilage volume and thickness, and measurement of relaxation times (T2 and T1Rho) are presented. In addition, the delayed uptake of Gadolinium DTPA as a marker of proteoglycan depletion is also reviewed. The cross-sectional and longitudinal studies using these imaging techniques show promise for cartilage assessment and for the study of osteoarthritis.
Blumenkrantz
G
G
Musculoskeletal and Quantitative Imaging Research Group, Department of Radiology, University of California, San Francisco, San Francisco, CA, USA.
Majumdar
S
S
D002358:Cartilage, Articular / Q000000981:diagnostic imaging / Q000473:pathology*; D019786:Gadolinium DTPA / Q000378:metabolism; D006801:Humans; D007719:Knee Joint / Q000000981:diagnostic imaging; D008279:Magnetic Resonance Imaging / Q000379:methods*; D010003:Osteoarthritis / Q000175:diagnosis* / Q000000981:diagnostic imaging; D020370:Osteoarthritis, Knee / Q000175:diagnosis / Q000000981:diagnostic imaging; D011859:Radiography
D019786:Gadolinium DTPA