Comparison of the extent of delayed-enhancement cardiac magnetic resonance imaging with and without phase-sensitive reconstruction at 3.0 T.
OBJECTIVE
To evaluate phase-sensitive reconstructed images versus magnitude images generated by an inversion recovery pulse sequence for the determination of myocardial infarct size in delayed-enhancement cardiac magnetic resonance (DE-CMR) at 3 T.


METHODS
Thirty patients were examined at 3 T and DE images were obtained 10 minutes after contrast agent administration using a phase-sensitive breath-hold segmented inversion recovery gradient echo sequence. From magnitude and phase images, the percentage of hyperenhanced myocardium was expressed. Contrast-to-noise ratio (CNR) measurements were performed in hyperenhanced and normal myocardium.


RESULTS
We observed excellent correlation and concordance between hyperenhanced myocardium determined on phase-sensitive reconstructed and magnitude images. The mean CNR values were significantly higher in phase-sensitive reconstructed images compared with magnitude images (10.5 +/- 5.4 vs. 6.1 +/- 4.8; P < 0.001).


CONCLUSIONS
DE-CMR with phase-sensitive reconstruction at 3.0 T provides similar results to magnitude images, but with a significantly greater CNR between infarcted and normal myocardium.
Cochet
Alexandre
A
Unité d'IRM et LE2I (CNRS UMR 5158), CHU Hôpital d'enfants, Dijon, France. alexandre.cochet@neuf.fr
Lalande
Alain
A
Walker
Paul M
PM
Boichot
Christophe
C
Ciappuccini
Renaud
R
Cottin
Yves
Y
Wolf
Jean-Eric
JE
Brunotte
François
F
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002311:Cardiomyopathy, Dilated / Q000473:pathology*; D003287:Contrast Media; D005260:Female; D019786:Gadolinium DTPA; D006801:Humans; D007091:Image Processing, Computer-Assisted; D016014:Linear Models; D019028:Magnetic Resonance Imaging, Cine / Q000379:methods*; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000473:pathology*
D003287:Contrast Media; D019786:Gadolinium DTPA