title: [Experimental investigation of general toxiology of antioxidant eyedrops davicol].
abstract: Authors examined the toxicity of antioxidant eye drops--davikoli. Antioxidants play important role in protecting the body from the formation of very dangerous substances referred to as free radicals. On the basis of honey an eye drops with high antioxidant activity--davicoli has been developed. The ocular effects of eye drops have been measured in a placebo-controlled double-blind study in 44 mice, 44 rats, 40 sea pigs and 20 chinchilla rabbits. Preclinical study revealed that eye drops davikoli are safe and non-toxic. During the investigation anti-inflammation features of eye drops davicoli was discovered.
authors.forename: D G
authors.initials: DG
authors.lastname: Shengeliia
authors.forename: A D
authors.initials: AD
authors.lastname: Bakuridze
authors.forename: N A
authors.initials: NA
authors.lastname: Karanadze
authors.forename: G A
authors.initials: GA
authors.lastname: Mikaia
authors.forename: V S
authors.initials: VS
authors.lastname: Baliashvili
mesh_terms: D000287:Administration, Topical; D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000494:pharmacology; D000975:Antioxidants / Q000009:adverse effects / Q000494:pharmacology*; D045424:Complex Mixtures / Q000627:therapeutic use; D051379:Mice; D009883:Ophthalmic Solutions; D051381:Rats
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D000975:Antioxidants; D045424:Complex Mixtures; D009883:Ophthalmic Solutions