title: Propriospinal myoclonus: utility of magnetic resonance diffusion tensor imaging and fiber tracking.
abstract: Propriospinal myoclonus (PSM) is a rare movement disorder characterized by involuntary spinal-generated muscular jerks that spread rostrally and caudally to other spinally innervated muscles. Most patients have no clear etiology, and conventional MRI of the spinal cord is generally normal. Here we report the use of magnetic resonance diffusion tensor imaging (DTI) and fiber tracking to detect tract-specific abnormalities in a patient with propriospinal myoclonus. As the patient had the fragile-X premutation and antithyroid antibodies, spinal cord DTI abnormalities may be related to these conditions. Tract-specific analysis may provide new insights into the pathophysiology of propriospinal myoclonus.
authors.affiliation: Department of Neurology, Saint-Antoine Hospital, AP-HP, Paris, France.|CNRS UMR 7102, Paris VI University, Paris, France.
authors.forename: Emmanuel
authors.initials: E
authors.lastname: Roze
authors.affiliation: Department of Neurophysiology, Saint Antoine Hospital, AP-HP, Paris, France.|INSERM U732, Paris VI University, Paris, France.
authors.forename: Emmanuelle
authors.initials: E
authors.lastname: Apartis
authors.affiliation: Department of Neurology, Saint-Antoine Hospital, AP-HP, Paris, France.|INSERM U679, Paris, France.
authors.forename: Marie
authors.initials: M
authors.lastname: Vidailhet
authors.affiliation: Department of Neurology, Saint-Antoine Hospital, AP-HP, Paris, France.|INSERM U679, Paris, France.
authors.forename: Valérie
authors.initials: V
authors.lastname: Cochen
authors.affiliation: Department of Neurophysiology, Saint Antoine Hospital, AP-HP, Paris, France.|Department of Neurophysiology, Henri Mondor Hospital, AP-HP, Creteil, France.
authors.forename: Yara
authors.initials: Y
authors.lastname: Beaugendre
authors.affiliation: Department of Neurology, Saint-Antoine Hospital, AP-HP, Paris, France.|Department of Neurophysiology, Saint Antoine Hospital, AP-HP, Paris, France.|INSERM U732, Paris VI University, Paris, France.
authors.forename: Jean-Marc
authors.initials: JM
authors.lastname: Trocello
authors.affiliation: Department of Neuroradiology, Bicêtre Hospital, AP-HP, Paris, France.
authors.forename: Pierre
authors.initials: P
authors.lastname: Lasjaunias
authors.affiliation: Department of Neuroradiology, Bicêtre Hospital, AP-HP, Paris, France.
authors.forename: Denis
authors.initials: D
authors.lastname: Ducreux
mesh_terms: D038524:Diffusion Magnetic Resonance Imaging / Q000379:methods; D006801:Humans; D008297:Male; D008875:Middle Aged; D009207:Myoclonus / Q000175:diagnosis* / Q000503:physiopathology*; D009412:Nerve Fibers / Q000473:pathology*; D013116:Spinal Cord / Q000473:pathology* / Q000503:physiopathology*