Histoplasma phimosis: an uncommon presentation of a not uncommon pathogen.
Infection from Histoplasma capsulatum is usually subclinical, but it also can be disseminated in patients with a compromised immune status. Involvement of the external genitalia is a rare finding, occurring by direct contact or hematogenous spread. We present a case of histoplasma posthitis in a 71-year-old man, manifesting with the extremely unusual presentation of phimosis. The diagnosis was confirmed using an immunohistochemical stain.
Ariyanayagam-Baksh
Shashi M
SM
Department of Pathology, Lancaster General Hospital, Lancaster, PA 17604-3555, USA. smariyan@lancastergeneral.org
Baksh
Fabien K
FK
Cartun
Richard W
RW
Sieber
Paul R
PR
D000368:Aged; D000935:Antifungal Agents / Q000627:therapeutic use; D015415:Biomarkers / Q000378:metabolism; D002944:Circumcision, Male; D052816:Foreskin / Q000378:metabolism / Q000473:pathology; D006658:Histoplasma / Q000302:isolation & purification / Q000472:pathogenicity*; D006660:Histoplasmosis / Q000378:metabolism / Q000473:pathology* / Q000628:therapy; D006801:Humans; D007124:Immunoenzyme Techniques; D017964:Itraconazole / Q000627:therapeutic use; D008297:Male; D010688:Phimosis / Q000382:microbiology / Q000473:pathology* / Q000628:therapy; D016896:Treatment Outcome
D000935:Antifungal Agents; D015415:Biomarkers; D017964:Itraconazole