title: Easy access to new heterocyclic systems: 1,4-oxazine and substituted 1,4-oxazines.
abstract: In the course of our investigations on the synthesis of new nitrogen heterocyclic derivatives, we were interested in the synthesis and study of new 1,4-oxazine rings. To this aim, the desired bisvinylphosphate was prepared from N-Boc morpholine-3,5-dione and was then engaged in palladium-catalyzed reactions (reduction, Suzuki, and Stille cross-coupling reactions). The 1,4-oxazine and its corresponding 3,5-disubstituted derivatives were obtained in fair to good yields and were then functionalized under anionic conditions.
authors.affiliation: ICOA, UMR 6005, Université d'Orléans, BP 6759, 45067 Orléans cedex 2, France.
authors.forename: Elise
authors.initials: E
authors.lastname: Claveau
authors.forename: Isabelle
authors.initials: I
authors.lastname: Gillaizeau
authors.forename: Jérome
authors.initials: J
authors.lastname: Blu
authors.forename: Amélie
authors.initials: A
authors.lastname: Bruel
authors.forename: Gérard
authors.initials: G
authors.lastname: Coudert
mesh_terms: D002384:Catalysis; D015394:Molecular Structure; D063065:Organophosphonates / Q000737:chemistry; D010078:Oxazines / Q000737:chemistry*; D014753:Vinyl Compounds / Q000737:chemistry
chemical_list: D063065:Organophosphonates; D010078:Oxazines; D014753:Vinyl Compounds; C433467:vinylphosphonic acid