title: Health-related quality of life during the first year after severe brain trauma with and without polytrauma.
abstract: OBJECTIVE
  The increasing number of patients surviving severe traumatic brain injury (sTBI) but with significant sensorimotor and neuropsychological deficits is a challenge to rehabilitation medicine. So far, most research initiatives have focused on mortality rates, physiological or economic parameters to estimate therapeutic effects of rehabilitation strategies. Investigations on health-related quality of life (HRQoL) after TBI with and without concomitant polytrauma are rare compared to other disorders.
  
  
  METHODS
  A prospective study was conducted to investigate HRQoL using the SF-36 questionnaire in 49 patients with sTBI (Glasgow Coma Scale < 9 for more than 24 hours) with and without concomitant polytrauma 6 and 12 months after injury.
  
  
  RESULTS
  The SF-36 score profiles 6 and 12 months after trauma were similar. Scores 12 months after trauma, however, were higher in 7/8 dimensions indicating an improvement over time. Similar observations were made for physical and mental sum scores. There was no difference in the SF-36 scoring pattern between the patients with isolated TBI and the patients with concomitant polytrauma, except for physical functioning after 12 months.
  
  
  CONCLUSIONS
  While there is significant overall improvement of HRQoL over time, sTBI appears to bear major influence on post-traumatic HRQoL and outcome.
authors.affiliation: Department of Neurosurgery, University of Cologne, Cologne, Germany. marcela.lippert.gruener@medizin.uni-koeln.de
authors.forename: Marcela
authors.initials: M
authors.lastname: Lippert-Grüner
authors.forename: Marc
authors.initials: M
authors.lastname: Maegele
authors.forename: Heinz
authors.initials: H
authors.lastname: Haverkamp
authors.forename: Norfrid
authors.initials: N
authors.lastname: Klug
authors.forename: Christoph
authors.initials: C
authors.lastname: Wedekind
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001930:Brain Injuries / Q000150:complications* / Q000175:diagnosis / Q000534:rehabilitation; D016022:Case-Control Studies; D015331:Cohort Studies; D005260:Female; D015600:Glasgow Coma Scale; D006304:Health Status; D006306:Health Surveys; D006801:Humans; D015601:Injury Severity Score; D008297:Male; D008875:Middle Aged; D009104:Multiple Trauma / Q000150:complications* / Q000175:diagnosis / Q000534:rehabilitation; D011379:Prognosis; D011788:Quality of Life; D013997:Time Factors