Metal-enhanced singlet oxygen generation: a consequence of plasmon enhanced triplet yields.
In this Rapid Communication, we report the first observation of Metal-Enhanced singlet oxygen generation (ME(1)O(2)). Rose Bengal in close proximity to Silver Island Films (SiFs) can generate more singlet oxygen, a three-fold increase observed, as compared to an identical glass control sample but containing no silver. The enhanced absorption of the photo-sensitizer, due to coupling to silver surface plasmons, facilitates enhanced singlet oxygen generation. The singlet oxygen yield can potentially be adjusted by modifying the choice of MEF (Metal-Enhanced Fluorescence) & MEP (Metal Enhance Phosphorescence) parameters, such as distance dependence for plasmon coupling and wavelength emission of the coupling fluorophore. This is a most helpful observation in understanding the interactions between plasmons and lumophores, and this approach may well be of significance for singlet oxygen based clinical therapy.
Zhang
Yongxia
Y
Institute of Fluorescence, Laboratory for Advanced Medical Plasmonics, Medical Biotechnology Center, University of Maryland Biotechnology Institute, 725 West Lombard St, Baltimore, MD 21201, USA.
Aslan
Kadir
K
Previte
Michael J R
MJ
Geddes
Chris D
CD
D005453:Fluorescence; D005456:Fluorescent Dyes; D008163:Luminescent Measurements; D008670:Metals / Q000737:chemistry*; D010777:Photochemistry; D010778:Photochemotherapy; D012395:Rose Bengal; D012834:Silver / Q000737:chemistry; D026082:Singlet Oxygen / Q000737:chemistry*; D020349:Surface Plasmon Resonance
D005456:Fluorescent Dyes; D008670:Metals; D026082:Singlet Oxygen; D012395:Rose Bengal; D012834:Silver