title: [Effects of the long-term tamponade with Densiron on the lens].
abstract: BACKGROUND
  This study aims to analyse the long-term effect of Densiron on the crystalline lens.
  
  
  METHODS
  Eleven patients (53-77 years old) underwent macular surgery with pars plana vitrectomy and intraocular tamponade with Densiron. After 2-4 months the Densiron was removed. The lens was extracted by phacoemulsification and an intraocular lens was implanted. Visual acuity, slit-lamp examination and fundus ophthalmoscopy were performed pre- and postoperatively. During surgery the anterior chamber, the lens und the posterior capsule of the lens were photographed and analysed.
  
  
  RESULTS
  All patients (mean age: 68 +/- 7 years) developed a nuclear cataract combined with a posterior capsule opacification. Four patients demonstrated vacuoles within the lens cortex and in five patients a pseudohypopyon consisting of emulsified Densiron was found. Mean visual acuity was 0.1 before removal of Densiron and 0.1 postoperatively.
  
  
  CONCLUSIONS
  Long-term tamponade with Densiron was complicated by early cataract formation in patients aged 68 years on average. The additional posterior capsule opacification showed a distinct pattern and localisation when compared to the use of 5000 mPas-silicone oil as tamponade.
authors.affiliation: Zentrum für Augenheilkunde der Universität zu Köln. alappas2000@yahoo.com
authors.forename: A
authors.initials: A
authors.lastname: Lappas
authors.forename: B
authors.initials: B
authors.lastname: Kirchhof
authors.forename: W
authors.initials: W
authors.lastname: Konen
mesh_terms: D000368:Aged; D002386:Cataract / Q000139:chemically induced* / Q000175:diagnosis*; D005260:Female; D005901:Glaucoma / Q000139:chemically induced* / Q000175:diagnosis*; D006801:Humans; D007908:Lens, Crystalline / Q000187:drug effects*; D008297:Male; D008875:Middle Aged; D012827:Silicone Oils / Q000009:adverse effects*; D016896:Treatment Outcome
chemical_list: D012827:Silicone Oils; C515608:densiron