Clomiphene citrate-induced follicular development in the presence of an ovarian ectopic pregnancy.
OBJECTIVE
To describe a case of a patient who had multiple follicular growth in the presence of an undiagnosed ectopic pregnancy (EP).


METHODS
Case report.


METHODS
In vitro fertilization unit at a university hospital.


METHODS
A 34-year-old patient with secondary infertility.


METHODS
Superovulation with clomiphene citrate (CC) and IUI.


METHODS
Follicular development with CC stimulation documented by transvaginal ultrasound and beta-hCG levels.


RESULTS
Two co-dominant follicles were observed with mean diameters of 22 mm and 24 mm. The patient had unexpectedly high levels of beta-hCG at the time of missed menses and was subsequently diagnosed with an ovarian EP.


CONCLUSIONS
Multiple follicular growths can occur in response to CC in spite of the presence of an ovarian EP.
Bayrak
Aykut
A
Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology and Infertility, University of Southern California-Keck School of Medicine, Los Angeles, California, USA. Aykutb@aol.com
Fogle
Robin H
RH
Paulson
Richard J
RJ
D000328:Adult; D002996:Clomiphene / Q000009:adverse effects / Q000494:pharmacology*; D005260:Female; D005300:Fertility Agents, Female / Q000009:adverse effects / Q000494:pharmacology; D005307:Fertilization in Vitro / Q000009:adverse effects; D006801:Humans; D033162:Incidental Findings; D006080:Ovarian Follicle / Q000187:drug effects* / Q000254:growth & development*; D010062:Ovulation Induction / Q000379:methods; D011247:Pregnancy; D011271:Pregnancy, Ectopic / Q000175:diagnosis*
D005300:Fertility Agents, Female; D002996:Clomiphene