title: Antiphospholipid syndrome in pregnancy.
abstract: Antiphospholipid syndrome (APS) is frequently associated with complications during pregnancy. Miscarriage and maternal thrombosis are the most common problems, but prematurity, intrauterine growth retardation, pregnancy-induced hypertensive disorders, and pulmonary hypertension can complicate pregnancy as well. The correct treatment of these women requires an accurate preconceptual counseling and a close collaboration between obstetricians and physicians. Doppler studies of the umbilical and uterine arteries play an important role in predicting APS-related complications during pregnancy.
authors.affiliation: Department of Internal Medicine, Hospital de Cruces, University of the Basque Country, 48903-Bizkaia, Spain.
authors.forename: Guillermo
authors.initials: G
authors.lastname: Ruiz-Irastorza
authors.forename: Munther A
authors.initials: MA
authors.lastname: Khamashta
mesh_terms: D000022:Abortion, Spontaneous / Q000453:epidemiology; D000925:Anticoagulants / Q000627:therapeutic use; D016736:Antiphospholipid Syndrome / Q000175:diagnosis* / Q000453:epidemiology; D005260:Female; D006493:Heparin / Q000627:therapeutic use; D006801:Humans; D006976:Hypertension, Pulmonary / Q000175:diagnosis / Q000503:physiopathology; D010024:Osteoporosis / Q000503:physiopathology; D011247:Pregnancy; D011248:Pregnancy Complications / Q000175:diagnosis* / Q000453:epidemiology / Q000503:physiopathology; D011256:Pregnancy Outcome; D018566:Pregnancy, High-Risk; D013927:Thrombosis / Q000517:prevention & control
chemical_list: D000925:Anticoagulants; D006493:Heparin