title: Proliferating trichilemmal cyst of the eyelid.
abstract: OBJECTIVE
  To report a case of proliferating trichilemmal cyst in a 55-year-old woman.
  
  
  METHODS
  Observational case report.
  
  
  METHODS
  A 55-year-old woman sought treatment for a mass in the right upper eyelid. The lesion was excised twice previously, and recurred. The mass was reexcised and examined histopathologically.
  
  
  RESULTS
  Light microscopy showed a cystic lesion lined by stratified squamous epithelium with a compact layer of eosinophilic keratin without granular cell layer. There was no atypia, mitosis, or stromal invasion.
  
  
  CONCLUSIONS
  Although proliferating trichilemmal cyst shows benign histopathologic features, clinical manifestations may mimic those of more aggressive tumors with local recurrences or distant metastasis. Wide excision of the lesion and close long-term follow-up is recommended.
authors.affiliation: Department of Ophthalmology, Emory University School of Medicine, Atlanta, Georgia, USA.
authors.forename: Shin J
authors.initials: SJ
authors.lastname: Kang
authors.forename: Ted H
authors.initials: TH
authors.lastname: Wojno
authors.forename: Hans E
authors.initials: HE
authors.lastname: Grossniklaus
mesh_terms: D049109:Cell Proliferation; D004804:Eosinophils / Q000473:pathology; D004814:Epidermal Cyst / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D005141:Eyelid Diseases / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D005260:Female; D006801:Humans; D007633:Keratins / Q000378:metabolism; D008875:Middle Aged; D008938:Mitosis; D012871:Skin Diseases / Q000378:metabolism / Q000473:pathology* / Q000601:surgery
chemical_list: D007633:Keratins