title: Tilescope: online analysis pipeline for high-density tiling microarray data.
abstract: We developed Tilescope, a fully integrated data processing pipeline for analyzing high-density tiling-array data http://tilescope.gersteinlab.org. In a completely automated fashion, Tilescope will normalize signals between channels and across arrays, combine replicate experiments, score each array element, and identify genomic features. The program is designed with a modular, three-tiered architecture, facilitating parallelism, and a graphic user-friendly interface, presenting results in an organized web page, downloadable for further analysis.
authors.affiliation: Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06520, USA. zhengdong.zhang@yale.edu
authors.forename: Zhengdong D
authors.initials: ZD
authors.lastname: Zhang
authors.forename: Joel
authors.initials: J
authors.lastname: Rozowsky
authors.forename: Hugo Y K
authors.initials: HY
authors.lastname: Lam
authors.forename: Jiang
authors.initials: J
authors.lastname: Du
authors.forename: Michael
authors.initials: M
authors.lastname: Snyder
authors.forename: Mark
authors.initials: M
authors.lastname: Gerstein
mesh_terms: D003196:Computer Graphics; D003627:Data Interpretation, Statistical; D020869:Gene Expression Profiling / Q000592:standards / Q000706:statistics & numerical data; D015233:Models, Statistical; D020411:Oligonucleotide Array Sequence Analysis / Q000592:standards* / Q000706:statistics & numerical data; D012015:Reference Standards; D012984:Software