Long-term outcome in ocular intractable surface disease with Seoul-type keratoprosthesis.
OBJECTIVE
To evaluate the long-term clinical efficacy of the Seoul-type keratoprosthesis (S-KPro).


METHODS
S-KPros were implanted into 4 unsighted and 5 sighted eyes in 9 patients: 6 patients were diagnosed with Stevens-Johnson syndrome, 2 had chemical burns, and 1 suffered from ocular pemphigoid. The preoperative visual acuity ranged from light perception to hand motion. The average follow-up period was 62.8 months. We evaluated several clinical factors, including visual acuity, visual field, number of additional grafting procedures, number of capsulotomy procedures, and the interval between retinal detachment and skirt exposure.


RESULTS
The S-KPro showed anatomic success for an average of 62.8 months in 66.7% of the eyes. The average visual acuity preservation time was 31.6 months. Localized glaucomatous visual field defect was not found in any of the sighted patients; however, diffuse visual field constriction was observed after long-term follow-up. Average time of skirt exposure and mean number of additional grafting procedures were 12.9 months and 2.44, respectively. Retinal detachments were developed in all the patients at a mean time interval of 2 months after S-KPro exchange.


CONCLUSIONS
S-KPro achieved visual rehabilitation for an average of 31.6 months with long-term anatomic stability in patients with severe intractable ocular surface disease.
Kim
Mee Kum
MK
Department of Ophthalmology, Seoul National University Hospital, Seoul, Korea.
Lee
Sang Mok
SM
Lee
Jae Lim
JL
Chung
Tae Young
TY
Kim
Young Ha
YH
Wee
Won Ryang
WR
Lee
Jin Hak
JH
D000328:Adult; D001187:Artificial Organs; D002057:Burns, Chemical / Q000601:surgery; D003315:Cornea; D003316:Corneal Diseases / Q000503:physiopathology / Q000601:surgery*; D005126:Eye Burns / Q000139:chemically induced; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D010390:Pemphigoid, Benign Mucous Membrane / Q000601:surgery; D019919:Prosthesis Implantation; D013262:Stevens-Johnson Syndrome / Q000601:surgery; D016896:Treatment Outcome; D014786:Vision Disorders / Q000503:physiopathology / Q000534:rehabilitation*; D014792:Visual Acuity / Q000502:physiology; D014794:Visual Fields / Q000502:physiology