[Depression as a side effect of alpha-interferon: mechanisms of development and criteria for experimental evaluation].
Possible mechanisms of the development of depression as a side effect of the a-interferon are reviewed. Methods used for the characterization of depressive states in experiment are considered.
Madzhumder
I S
IS
Kalenikova
E I
EI
Gorodetskaia
E A
EA
Siutkin
V E
VE
D000818:Animals; D016207:Cytokines / Q000378:metabolism; D003866:Depressive Disorder / Q000139:chemically induced* / Q000378:metabolism / Q000503:physiopathology; D005227:Fatty Acids / Q000378:metabolism; D006801:Humans; D016898:Interferon-alpha / Q000009:adverse effects* / Q000627:therapeutic use; D012701:Serotonin / Q000378:metabolism
D016207:Cytokines; D005227:Fatty Acids; D016898:Interferon-alpha; D012701:Serotonin