Lupus anticoagulant and thrombosis following Henoch-Schonlein purpura.
A male adolescent developed a sinovenous thrombosis 4 weeks following a Henoch-Schonlein purpura episode. A hypercoagulation evaluation revealed a positive lupus anticoagulant. This suggests an association between Henoch-Schonlein purpura and antiphospholipid antibody syndrome and is the first report of sinovenous thrombosis after Henoch-Schonlein purpura that was likely due to elevated antiphospholipids. Children who develop Henoch-Schonlein purpura with neurologic features including headache should be evaluated for sinovenous thrombosis and a hypercoagulable state.
Abend
Nicholas S
NS
Division of Neurology, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA. abend@email.chop.edu
Licht
Daniel J
DJ
Spencer
Charles H
CH
D000293:Adolescent; D006801:Humans; D011695:IgA Vasculitis / Q000097:blood* / Q000150:complications*; D016682:Lupus Coagulation Inhibitor / Q000097:blood*; D008297:Male; D012851:Sinus Thrombosis, Intracranial / Q000097:blood* / Q000175:diagnosis / Q000209:etiology*
D016682:Lupus Coagulation Inhibitor