[Primary cutaneous aspergillosis in a leukemic child].
Primary cutaneous aspergillosis is a rare cutaneous disease that usually affects immunodepressed patients of any age. The most common associated disorders in children are leukemias and lymphomas although it can also occur in neonates and preterms due to their intrinsic immunological immaturity. We report the case of a 4-year-old boy diagnosed of acute lymphoblastic leukemia that, during chemotherapy, developed an ulceronecrotic inflammatory cutaneous lesion in the venopuncture area of the left forearm, and whose microbiological culture was positive for Aspergillus flavus.
Torrelo
A
A
Servicios de Dermatología, Hospital del Niño Jesús, Madrid, España. atorrelo@aedv.es
Hernández-Martín
A
A
Scaglione
C
C
Madero
L
L
Colmenero
I
I
Zambrano
A
A
D000666:Amphotericin B / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects / Q000627:therapeutic use; D001228:Aspergillosis / Q000209:etiology*; D001231:Aspergillus flavus / Q000302:isolation & purification*; D002675:Child, Preschool; D003881:Dermatomycoses / Q000209:etiology*; D006801:Humans; D016867:Immunocompromised Host; D008297:Male; D009503:Neutropenia / Q000139:chemically induced / Q000150:complications; D009894:Opportunistic Infections / Q000209:etiology* / Q000382:microbiology; D018962:Phlebotomy / Q000009:adverse effects*; D015452:Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / Q000150:complications* / Q000188:drug therapy; D012883:Skin Ulcer / Q000209:etiology / Q000382:microbiology; D014946:Wound Infection / Q000209:etiology* / Q000382:microbiology
D000935:Antifungal Agents; C068538:liposomal amphotericin B; D000666:Amphotericin B