[Evaluation of the degree of respiratory failure in patients with chronic obstructive pulmonary disease].
Thirty practically healthy individuals and 111 patients suffering from chronic obstructive pulmonary disease (COPD) with I to III degree chronic respiratory failure (CRF) were examined. The study established a negative correlation between partial oxygen pressure in arterial blood (AB), the degree of bronchial obstruction, hemoglobin saturation, and the degree of CRF. It was found that the degree of CRF was in a significant correlation with the degree of pulmonary physiological (alveolar) shunt and the degree of hypercapnia. The author proposes an algorithm for precise determination of the degree of CRF that includes calculation of alveolar shunt as an integral parameter reflecting the degree of AB gas changes.
Gnoevykh
V V
VV
D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D029424:Pulmonary Disease, Chronic Obstructive / Q000453:epidemiology*; D012131:Respiratory Insufficiency / Q000175:diagnosis* / Q000453:epidemiology*; D012720:Severity of Illness Index