[Eruptive pseudoangiomatosis: study of 7 cases].
BACKGROUND
Eruptive pseudoangiomatosis consists in the acute development of small vascular lesions in the face and extremities that resolve in several weeks without scarring. Lesions are described as 3-4 mm asymptomatic macules and papules with peripheral whitish halo that blanch upon pressure. Initially it was considered a disease limited to children but it has also been described in adults. It overlaps with the entity known in Japan as <<erythema punctatum Higuchi>>, possibly caused by an insect named Culex pipiens pallens.


METHODS
We report a serie of 7 patients that consulted for lesions compatible with eruptive pseudoangiomatosis. We performed a detailed clinical history and histological, microbiological and serological studies. Follow-up time was up to 4 years.


RESULTS
Eighty-five percent of patients were women and the mean age was 62 years. All cases appeared in spring/summer and 71 % relapsed. Lesions predominated in the face and extremities and the outbreak lasted 2-4 weeks. The anamnesis did not disclose any specific etiologic agent in any of the cases. Complete laboratory tests including serologies and cultures were negative or within normal limits. Histological study revealed vascular dilatation in all cases with endothelial cell protrusion and a peripheral lymphohistiocytic infiltrate.


CONCLUSIONS
Currently, the etiology of this entity is not well established although it probably represents a reactive disorder to different etiologic processes.
Pérez-Barrio
S
S
Servicio de Dermatología, Hospital de Cruces, Baracaldo, Vizcaya, España. spbarrio@hotmail.com
Gardeazábal
J
J
Acebo
E
E
Martínez de Lagrán
Z
Z
Díaz-Pérez
J L
JL
D000328:Adult; D000368:Aged; D000818:Animals; D001706:Biopsy; D003465:Culex; D003937:Diagnosis, Differential; D004890:Erythema / Q000175:diagnosis* / Q000209:etiology / Q000473:pathology; D005121:Extremities; D005148:Facial Dermatoses / Q000175:diagnosis / Q000209:etiology / Q000473:pathology; D005500:Follow-Up Studies; D006391:Hemangioma / Q000175:diagnosis; D006801:Humans; D007299:Insect Bites and Stings / Q000175:diagnosis; D008297:Male; D008875:Middle Aged; D012878:Skin Neoplasms / Q000175:diagnosis