[Training after percutaneous coronary intervention- an undervalued treatment option?].
BACKGROUND
Even though regular exercise training after myocardial infarction reduces morbidity and mortality, training after percutaneous coronary intervention (PCI) is still not part of the standard treatment. This article reviews the documentation on exercise training with coronary artery disease and examines the effect on pathophysiological mechanisms that play an important role in the progression of coronary artery disease and restenosis after PCI with stent implantation.


METHODS
The article is based on a search in PubMed and the Cochcrane database.


CONCLUSIONS
The effect of regular exercise training on morbitity and mortality in coronary artery disease without myocardial infarction is not well documented. But the data indicate that training has an antiinflammatory effect in the vessel wall. Regular exercise training in these patients increases the bioavailibility of nitric oxide and is a non-pharmacological option to improve the endothelial function. Prospective, randomised, controlled trials are needed to evaluate whether there is a beneficial clinical effect of training after PCI treatment.
Munk
Peter Scott
PS
Hjerteavdelingen Stavanger universitetsjukehus, 4068 Stavanger. smpe@sus.no
Larsen
Alf Inge
AI
D015906:Angioplasty, Balloon, Coronary / Q000009:adverse effects / Q000401:mortality / Q000534:rehabilitation*; D015415:Biomarkers / Q000097:blood; D003327:Coronary Disease / Q000401:mortality / Q000503:physiopathology / Q000628:therapy*; D023903:Coronary Restenosis / Q000517:prevention & control; D018450:Disease Progression; D004730:Endothelium, Vascular / Q000503:physiopathology; D005081:Exercise Therapy; D006801:Humans; D018836:Inflammation Mediators / Q000097:blood; D015607:Stents; D016896:Treatment Outcome
D015415:Biomarkers; D018836:Inflammation Mediators