Localized retinal nerve fiber layer defects and visual field abnormalities by humphrey matrix frequency doubling technology perimetry.
OBJECTIVE
To investigate the ability of frequency doubling technology (FDT) perimetry to identify eyes with a localized retinal nerve fiber layer (RNFL) defect and normal Humphrey C30-2 SITA-Standard visual field (HVF).


METHODS
Retrospective case-control study.


METHODS
Fifty-four eyes were divided into two groups, an abnormal (n = 29) and a normal (n = 25) FDT perimetry group. Approximation of the RNFL defect to the macula (angle alpha) and width of the defect (angle beta) were measured by RNFL photograph and compared between two groups.


RESULTS
Angle alpha and angle beta were significantly different between two groups (P < .001 by Mann-Whitney U test, respectively). A multivariate logistic regression analysis demonstrated that only angle beta was significantly associated with FDT perimetry abnormalities (P = .002).


CONCLUSIONS
Only 53.7% of the eyes with a localized RNFL defect and normal HVF had visual field abnormalities identified by FDT perimetry. Width of the RNFL defect was more strongly associated with FDT perimetry abnormalities than location of the defect.
Lee
Min Joung
MJ
Department of Ophthalmology, Seoul National University Hospital, Seoul, Korea.
Kim
Dong Myung
DM
Jeoung
Jin Wook
JW
Hwang
Seung-Sik
SS
Kim
Tae Woo
TW
Park
Ki Ho
KH
D000328:Adult; D000368:Aged; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009412:Nerve Fibers / Q000473:pathology*; D009901:Optic Nerve Diseases / Q000175:diagnosis*; D012165:Retinal Ganglion Cells / Q000473:pathology*; D012189:Retrospective Studies; D014786:Vision Disorders / Q000175:diagnosis*; D058609:Visual Field Tests / Q000379:methods*; D014794:Visual Fields