title: Weight gain prevention among women.
abstract: OBJECTIVE
  Women 25 to 45 years old are at risk for weight gain and future obesity. This trial was designed to evaluate the efficacy of two interventions relative to a control group in preventing weight gain among normal or overweight women and to identify demographic, behavioral, and psychosocial factors related to weight gain prevention.
  
  
  METHODS
  Healthy women (N = 284), ages 25 to 44, with BMI < 30 were randomized to one of three intervention conditions: a clinic-based group, a correspondence course, or an information-only control. Intervention was provided over 2 years, with a follow-up at Year 3. BMI and factors related to eating and weight were assessed yearly.
  
  
  RESULTS
  Over the 3-year study period, 40% (n = 114) of the women remained at or below baseline body weight (+/-2 lbs), and 60% gained weight (>2 lbs). Intervention had no effect on weight over time. Independently of intervention, women who were older, not actively dieting to lose weight, and who reported less perceived hunger at baseline were more likely to be successful at weight maintenance. Weight maintenance also was associated with increasing dietary restraint (conscious thoughts and purposeful behaviors to control calorie intake) and decreasing dietary disinhibition (the tendency to lose control over eating) over time.
  
  
  CONCLUSIONS
  This study raises concern about the feasibility and efficacy of weight gain prevention interventions because most women were interested in weight loss, rather than weight gain prevention, and the interventions had no effect on weight stability. Novel approaches to the prevention of weight gain are needed.
authors.affiliation: Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, 3811 O'Hara Street, Pittsburgh, PA 15213, USA.
authors.forename: Michele D
authors.initials: MD
authors.lastname: Levine
authors.forename: Mary Lou
authors.initials: ML
authors.lastname: Klem
authors.forename: Melissa A
authors.initials: MA
authors.lastname: Kalarchian
authors.forename: Rena R
authors.initials: RR
authors.lastname: Wing
authors.forename: Lisa
authors.initials: L
authors.lastname: Weissfeld
authors.forename: Li
authors.initials: L
authors.lastname: Qin
authors.forename: Marsha D
authors.initials: MD
authors.lastname: Marcus
mesh_terms: D000328:Adult; D015992:Body Mass Index; D005260:Female; D006801:Humans; D008875:Middle Aged; D009765:Obesity / Q000453:epidemiology / Q000517:prevention & control* / Q000534:rehabilitation; D010353:Patient Education as Topic / Q000379:methods; D015995:Prevalence; D014481:United States / Q000453:epidemiology; D015430:Weight Gain / Q000502:physiology*; D015431:Weight Loss / Q000502:physiology*