[Comparative action of melatonin and bilobil on light perception and psychophysiological indices in patients with cerebral trauma anamnesis].
Pineal hormone melatonin (melaxen preparation) and a typical cognitive enhancer Ginkgo biloba (bilobil preparation) decreased the retinal light sensitivity thresholds upon two-week administration in young (aged 19-23) patients with cerebral trauma anamnesis. This effect was more significant in evening than in the morning hours. Both drugs also attenuated the reactive anxiety (bilobil was slightly superior to melaxen in this respect) and insignificantly increased the volume of acoustic memory. The observed similarity of the psychotropic effect of two preparations allows melatonin to be classified into nootropic agents.
Arushanian
E B
EB
Ovanesov
K B
KB
Ovanesova
I M
IM
D000328:Adult; D001007:Anxiety / Q000188:drug therapy / Q000209:etiology; D001930:Brain Injuries / Q000150:complications* / Q000503:physiopathology / Q000523:psychology; D002940:Circadian Rhythm; D005260:Female; D020441:Ginkgo biloba / Q000737:chemistry*; D006801:Humans; D008297:Male; D008550:Melatonin / Q000627:therapeutic use*; D008568:Memory / Q000187:drug effects; D018697:Nootropic Agents / Q000627:therapeutic use*; D010775:Photic Stimulation; D020795:Photophobia / Q000209:etiology / Q000503:physiopathology; D010936:Plant Extracts / Q000627:therapeutic use; D012160:Retina / Q000187:drug effects / Q000503:physiopathology; D014796:Visual Perception / Q000187:drug effects*
D018697:Nootropic Agents; D010936:Plant Extracts; D008550:Melatonin