title: Does l-carnitine have any effect on cold preservation injury of non-fatty liver in the University of Wisconsin solution?
abstract: OBJECTIVE
  To evaluate the protective effect of l-carnitine on liver tissue preserved in University of Wisconsin (UW) solution.
  
  
  METHODS
  Twenty Wistar Albino rats were divided into two groups, a control (UW) group and a UW plus l-carnitine group. Retrieved liver grafts were preserved in UW and UW plus l-carnitine solutions at +4 degrees C. Preservation solution samples were assessed at 2, 24, 36, and 48 h to measure alanine aminotransferase and acid phosphatase activity. Tissue injury was scored on paraffin sections.
  
  
  RESULTS
  No micro or macrovacuolar fat droplets were observed in the tissue slices. l-Carnitine effectively decreased enzyme release when added to UW solution (P < 0.05).
  
  
  CONCLUSIONS
  In addition to fatty liver, l-carnitine might be a metabolic adjunct in preservation solutions for non-fatty liver within UW solution.
authors.affiliation: Department of Clinical Biochemistry, School of Medicine, Duzce University, Duzce, Turkey.
authors.forename: Abdurrahman
authors.initials: A
authors.lastname: Coskun
authors.forename: Omer
authors.initials: O
authors.lastname: Gunal
authors.forename: Ibrahim
authors.initials: I
authors.lastname: Sahin
authors.forename: Arif
authors.initials: A
authors.lastname: Aslaner
authors.forename: Umran
authors.initials: U
authors.lastname: Yildirim
authors.forename: Ozlem
authors.initials: O
authors.lastname: Yavuz