title: Oscillatory potentials of the slow-sequence multifocal ERG in primates extracted using the Matching Pursuit method.
abstract: This study used the Matching Pursuit (MP) method, a time-frequency analysis, to identify and characterize oscillatory potentials (OPs) in the primate electroretinogram (ERG). When the slow-sequence mfERG from the macular region of the retina was matched with Gabor functions, OPs were identified in two distinct bands: a high-frequency band peaking around 150 Hz that contributes to early OPs, and a low-frequency band peaking around 80 Hz that contributes to both early and late OPs. Pharmacological blockade and experimental glaucoma studies showed that the high-frequency OPs depend upon sodium-dependent spiking activity of retinal ganglion cells, whereas the low-frequency OPs depend primarily upon non-spiking activity of amacrine cells, and more distal retinal activity.
authors.affiliation: College of Optometry, University of Houston, Houston, TX, USA. franch9@hotmail.com
authors.forename: Wei
authors.initials: W
authors.lastname: Zhou
authors.forename: Nalini
authors.initials: N
authors.lastname: Rangaswamy
authors.forename: Periklis
authors.initials: P
authors.lastname: Ktonas
authors.forename: Laura J
authors.initials: LJ
authors.lastname: Frishman
mesh_terms: D000818:Animals; D004195:Disease Models, Animal; D004596:Electroretinography; D005901:Glaucoma / Q000503:physiopathology; D008251:Macaca; D016202:N-Methylaspartate; D010775:Photic Stimulation / Q000379:methods; D010875:Pipecolic Acids; D012160:Retina / Q000502:physiology* / Q000503:physiopathology; D012165:Retinal Ganglion Cells / Q000502:physiology; D012815:Signal Processing, Computer-Assisted; D013779:Tetrodotoxin; D005680:gamma-Aminobutyric Acid
chemical_list: D010875:Pipecolic Acids; D013779:Tetrodotoxin; C029262:2,3-piperidinedicarboxylic acid; D005680:gamma-Aminobutyric Acid; D016202:N-Methylaspartate