Headache and spontaneous low cerebrospinal fluid pressure syndrome.
We examined 59 consecutive patients presenting between 1993 and 2006 at our centre diagnosed with headache associated with spontaneous intracranial hypotension syndrome (SIH). Thirty-six (61%) patients were women; the mean age was 47 years (range 20-68). Cerebral MRI with contrast confirmed SIH in all patients. Headache characteristics were obtained by direct semistructured interview; in a minority of cases information was completed retrospectively through a phone call. All SIH patients suffered from headache. Early recognition of SIH may avoid dangerous worsening due to delayed diagnosis. Orthostatic headache, the main symptom, suggests the diagnosis.
Mea
E
E
Istituto Neurologico Carlo Besta, Via Celoria 11, I-20133, Milan, Italy.
Savoiardo
M
M
Chiapparini
L
L
Casucci
G
G
Bonavita
V
V
Bussone
G
G
Leone
M
M
D000328:Adult; D000368:Aged; D001921:Brain / Q000473:pathology / Q000503:physiopathology; D002550:Cerebral Veins / Q000473:pathology / Q000503:physiopathology; D015170:Cerebrospinal Fluid Pressure / Q000502:physiology; D003937:Diagnosis, Differential; D003951:Diagnostic Errors / Q000517:prevention & control*; D004388:Dura Mater / Q000473:pathology / Q000503:physiopathology; D005260:Female; D020773:Headache Disorders / Q000175:diagnosis* / Q000209:etiology* / Q000503:physiopathology; D006801:Humans; D019585:Intracranial Hypotension / Q000150:complications* / Q000175:diagnosis* / Q000503:physiopathology; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D008881:Migraine Disorders / Q000175:diagnosis; D011237:Predictive Value of Tests; D012189:Retrospective Studies; D013353:Subdural Effusion / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology; D013355:Subdural Space / Q000473:pathology / Q000503:physiopathology; D018781:Tension-Type Headache / Q000175:diagnosis