title: Three new sesquiterpenoids from the aerial parts of Homalomena occulta.
abstract: Three new eudesmane-type sesquiterpenoids, compounds 1-3, and eight known constituents, including mucrolidin (4), 1beta,4beta,7alpha-trihydroxyeudesmane (5), 1beta,4beta,6beta,11-tetrahydroxyeudesmane (6), oplodiol (7), bullatantriol (8), acetylbullatantriol (9), homalomenol (10), and maristeminol (11), were isolated from the aerial parts of Homalomena occulta. Their structures were determined by interpretation of spectroscopic and mass-spectrometric data, and their antimicrobial activities toward six different bacterial strains were tested. Most of the compounds showed weak antibacterial activities in an agar-diffusion assay.
authors.affiliation: State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, PR China.
authors.forename: Yi-Fen
authors.initials: YF
authors.lastname: Wang
authors.forename: Xian-You
authors.initials: XY
authors.lastname: Wang
authors.forename: Guo-Fang
authors.initials: GF
authors.lastname: Lai
authors.forename: Chun-Hua
authors.initials: CH
authors.lastname: Lu
authors.forename: Shi-De
authors.initials: SD
authors.lastname: Luo
mesh_terms: D000900:Anti-Bacterial Agents / Q000302:isolation & purification / Q000494:pharmacology*; D029064:Araceae / Q000737:chemistry*; D001562:Benzimidazoles / Q000302:isolation & purification / Q000494:pharmacology; D002681:China; D003517:Cyclopentanes / Q000302:isolation & purification / Q000494:pharmacology; D009284:Naphthols / Q000302:isolation & purification / Q000494:pharmacology; D012717:Sesquiterpenes / Q000302:isolation & purification / Q000494:pharmacology*
chemical_list: C436284:2-cyclopentyl-5-(5-isoquinolylsulfonyl)-6-nitro-1H-benzo(D)imidazole; D000900:Anti-Bacterial Agents; D001562:Benzimidazoles; D003517:Cyclopentanes; D009284:Naphthols; D012717:Sesquiterpenes; C487643:oplodiol