title: Gait parameters of treadmill versus overground locomotion in mouse.
abstract: Many studies of interest in motor behaviour and motor impairment in mice use equally treadmill or track as a routine test. However, the literature in mammals shows a wide difference of results between the kinematics of treadmill and overground locomotion. To study these discrepancies, we analyzed the locomotion of adult SWISS-OF1 mice over a large range of velocities using treadmill and overground track. The use of a high-speed video camera combined with cinefluoroscopic equipment allowed us to quantify in detail the various space and time parameters of limb kinematics. The results show that mice maintain the same gait pattern in both conditions. However, they also demonstrate that during treadmill exercise mice always exhibit higher stride frequency and consequently lower stride length. The relationship of the stance time and the swing time against the stride frequency are still the same in both conditions. We conclude that the conflict related to the discrepancy between the proprioceptive, vestibular, and visual inputs contribute to an increase in the stride frequency during the treadmill locomotion.
authors.affiliation: U.S.M. 0302, CNRS, MNHN, Univ. Paris 6, Collège de France, Paris Cedex 05, France. herbin@mnhn.fr
authors.forename: Marc
authors.initials: M
authors.lastname: Herbin
authors.forename: Rémi
authors.initials: R
authors.lastname: Hackert
authors.forename: Jean-Pierre
authors.initials: JP
authors.lastname: Gasc
authors.forename: Sabine
authors.initials: S
authors.lastname: Renous
mesh_terms: D000222:Adaptation, Physiological; D000818:Animals; D001696:Biomechanical Phenomena; D004777:Environment; D004867:Equipment Design; D005260:Female; D005684:Gait / Q000502:physiology*; D008124:Locomotion / Q000502:physiology*; D051379:Mice; D011434:Proprioception / Q000502:physiology*; D012044:Regression Analysis; D013499:Surface Properties; D014741:Video Recording