A systematic comparative and structural analysis of protein phosphorylation sites based on the mtcPTM database.
mtcPTM is an online repository of human and mouse phosphosites in which data are hierarchically organized to preserve biologically relevant experimental information, thus allowing straightforward comparisons of phosphorylation patterns found under different conditions. The database also contains the largest available collection of atomic models of phosphorylatable proteins. Detailed analysis of this structural dataset reveals that phosphorylation sites are found in a heterogeneous range of structural and sequence contexts. mtcPTM is available on the web http://www.mitocheck.org/cgi-bin/mtcPTM/search.
Jiménez
José L
JL
Wellcome Trust Sanger Institute, Genome Campus, Hinxton, Cambridge, CB10 1SA, UK. j_l_jimenez71@yahoo.es
Hegemann
Björn
B
Hutchins
James R A
JR
Peters
Jan-Michael
JM
Durbin
Richard
R
D000595:Amino Acid Sequence; D000818:Animals; D001665:Binding Sites; D030562:Databases, Protein; D006801:Humans; D051379:Mice; D010750:Phosphoproteins / Q000737:chemistry*; D010766:Phosphorylation; D011487:Protein Conformation; D011506:Proteins / Q000737:chemistry*; D040901:Proteomics / Q000379:methods
D010750:Phosphoproteins; D011506:Proteins