title: Imaging the addicted human brain.
abstract: Modern imaging techniques enable researchers to observe drug actions and consequences as they occur and persist in the brains of abusing and addicted individuals. This article presents the five most commonly used techniques, explains how each produces images, and describes how researchers interpret them. The authors give examples of key findings illustrating how each technique has extended and deepened our knowledge of the neurobiological bases of drug abuse and addiction, and they address potential clinical and therapeutic applications.
authors.affiliation: Medical Department, Brookhaven National Laboratory, Upton, NY 11973, USA. fowler@bnl.gov
authors.forename: Joanna S
authors.initials: JS
authors.lastname: Fowler
authors.forename: Nora D
authors.initials: ND
authors.lastname: Volkow
authors.forename: Cheryl A
authors.initials: CA
authors.lastname: Kassed
authors.forename: Linda
authors.initials: L
authors.lastname: Chang
mesh_terms: D019969:Amphetamine-Related Disorders / Q000503:physiopathology; D016739:Behavior, Addictive / Q000188:drug therapy / Q000503:physiopathology; D001921:Brain / Q000503:physiopathology*; D004298:Dopamine / Q000378:metabolism; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D011954:Receptors, Dopamine / Q000378:metabolism; D019966:Substance-Related Disorders / Q000188:drug therapy / Q000503:physiopathology*; D014054:Tomography
chemical_list: D011954:Receptors, Dopamine; D004298:Dopamine