title: Tonometer pHi monitoring of free jejunal grafts following pharyngolaryngoesophagectomy for hypopharyngeal or cervical esophageal cancer.
abstract: OBJECTIVE
  Graft failure is a critical complication associated with vascular occlusion in esophageal reconstruction with a free jejunal graft following pharyngolaryngoesophagectomy. In this study, we evaluated the usefulness of intramucosal pH (pHi) measurement using a tonometer to assess the graft viability.
  
  
  METHODS
  Two consecutive studies, the early phase study and the late phase study, were performed. Nineteen patients who underwent free jejunal transfer were enrolled in the early phase study before 1999 to determine the critical pHi value. In the late phase study after 2000 (n=16), anticoagulant treatment to prevent graft necrosis was performed in the patients having a pHi value under the critical level.
  
  
  RESULTS
  In the early phase study, vascular obstruction was not seen in 16 patients with pHi>7.10. Of 3 patients with pHi<7.10, 2 underwent regrafting because of jejunal graft necrosis by vascular obstruction. In the late phase study, reoperation was not required in 3 of 4 patients with pHi<7.10. Intraoperative vascular occlusion was found in 1 patient with a decline in pHi value and anticoagulant treatment was effective in 2 others.
  
  
  CONCLUSIONS
  The pHi measurement using a tonometer is useful for finding vascular problems in free jejunal grafts.
authors.affiliation: Second Department of Surgery, Hamamatsu University School of Medicine, Hamamatsu, Japan. kamikin@hama-med.ac.jp
authors.forename: Kinji
authors.initials: K
authors.lastname: Kamiya
authors.forename: Shohachi
authors.initials: S
authors.lastname: Suzuki
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Mineta
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Konno
mesh_terms: D000368:Aged; D004938:Esophageal Neoplasms / Q000601:surgery; D016629:Esophagectomy; D005260:Female; D006085:Graft Survival; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007012:Hypopharyngeal Neoplasms / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D007013:Hypopharynx / Q000473:pathology; D007583:Jejunum / Q000737:chemistry / Q000637:transplantation*; D007825:Laryngectomy; D008297:Male; D008875:Middle Aged; D037981:Neck Dissection; D009367:Neoplasm Staging; D010611:Pharyngectomy; D013997:Time Factors