title: [Round window catheter placement with dexamethasone perfusion for intractable sudden sensorineural hearing loss].
abstract: OBJECTIVE
  To investigate the efficacy of round window catheter placement with dexamethasone perfusion for 13 patients with intractable sudden sensorineural hearing loss (SSNHL).
  
  
  METHODS
  Dexamethasone (2.5 mg) was perfused transtympanically through round window catheter by Micro-infusion pump. The perfusion was taken twice a day and continued for an hour each time, for a total of 7 days.
  
  
  RESULTS
  Thirteen patients have been followed up for 1 month. Five of them (38.5%) were demonstrated a 17-54 dB improvement in pure-tone threshold average (PTA). The other 8 patients (61.5%) had no effect.
  
  
  CONCLUSIONS
  Round window catheter placement with dexamethasone perfusion is a cost-effective and useful treatment for SSNHL patients who had no effect through conventional therapy, although hearing thresholds of these patients had hardly improved to normal levels.
authors.affiliation: Department of Otolaryngology, the Second Hospital of Xiangya Medical College, Central South University, Changsha, 410011, China.
authors.forename: Xialing
authors.initials: X
authors.lastname: Sun
authors.forename: Jihao
authors.initials: J
authors.lastname: Ren
authors.forename: Yongde
authors.initials: Y
authors.lastname: Lu
authors.forename: Tuanfang
authors.initials: T
authors.lastname: Yin
authors.forename: Weijing
authors.initials: W
authors.lastname: Wu
authors.forename: Yueying
authors.initials: Y
authors.lastname: Tang
authors.forename: Binya
authors.initials: B
authors.lastname: Hu
mesh_terms: D000328:Adult; D000368:Aged; D002404:Catheterization; D003907:Dexamethasone / Q000008:administration & dosage* / Q000627:therapeutic use; D005260:Female; D006319:Hearing Loss, Sensorineural / Q000188:drug therapy*; D003639:Hearing Loss, Sudden / Q000188:drug therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012405:Round Window, Ear
chemical_list: D003907:Dexamethasone