An outbreak of HIV-1 subtype G among Italian injecting drug users.
We describe an outbreak of subtype G among injecting drug users (IDU) in northern Italy newly infected with HIV. We analysed pol gene sequences from samples of 139 individuals from different risk groups. Non-B subtypes were more frequently detected among IDU than in homosexual or heterosexual contacts. All G subtypes but one were found among IDU. The phylogenetic analysis indicated that the outbreak was of monophyletic origin and was caused by HIV-1 strains similar to those from western Africa.
Ciccozzi
Massimo
M
Epidemiology Unit, Department of Infectious, Parasite and Immune-mediated Diseases, Istituto Superiore di Sanità, Rome, Italy.
Montieri
Stefania
S
Salemi
Marco
M
De Oliveira
Tulio
T
Dorrucci
Maria
M
Sinicco
Alessandro
A
De Luca
Andrea
A
Giuliani
Massimo
M
Balotta
Claudia
C
Rezza
Giovanni
G
D001483:Base Sequence; D004196:Disease Outbreaks; D005260:Female; D015751:Genes, pol / Q000235:genetics; D015658:HIV Infections / Q000150:complications / Q000453:epidemiology* / Q000235:genetics; D015497:HIV-1 / Q000145:classification / Q000235:genetics*; D006801:Humans; D007558:Italy / Q000453:epidemiology; D008297:Male; D010802:Phylogeny; D011446:Prospective Studies; D019529:Sexuality; D015819:Substance Abuse, Intravenous / Q000150:complications / Q000453:epidemiology* / Q000235:genetics