[Sporotrichoid cutaneous infection by Mycobacterium haemophilum in an AIDS patient].
We report a case of primary cutaneous infection by Mycobacterium haemophilum after the bite of an aquarium fish in a severely immunodepressed AIDS patient. Clinical features consisted in nodular and ulcerative lesions that followed a sporotrichoid pattern. Histological study of nodular lesions showed a granulomatous dermatitis with numerous acid-fast bacilli. The mycobacterium was identified 3 months later by genetic hybridization from a cultive in solid medium. Combined therapy with isoniazid, rifampin, clarithromycin, ethambutol, amikacin and ciprofloxacin resulted in complete resolution of the lesions. Infection by Mycobacterium haemophilum is a rare mycobacteriosis that usually affects immunodepressed patients. The most common clinical manifestations are cutaneous lesions but the development of sporotrichoid nodular lymphangitis is exceptional.
Cameselle
D
D
Servicio de Dermatología, Hospital Universitario Insular, Las Palmas de Gran Canaria, España. dani.camel@hotmail.com
Hernández
J
J
Francès
A
A
Montenegro
T
T
Cañas
F
F
Borrego
L
L
D017088:AIDS-Related Opportunistic Infections / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology / Q000382:microbiology / Q000473:pathology; D000328:Adult; D000818:Animals; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000995:Antitubercular Agents / Q000627:therapeutic use; D001132:Arm; D001170:Arthritis, Infectious / Q000209:etiology; D001733:Bites and Stings / Q000150:complications; D023681:Cichlids; D024881:Drug Resistance, Bacterial; D004359:Drug Therapy, Combination; D005383:Finger Injuries / Q000150:complications*; D006099:Granuloma / Q000175:diagnosis / Q000209:etiology / Q000382:microbiology / Q000473:pathology; D006229:Hand Dermatoses / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology / Q000382:microbiology / Q000473:pathology; D006801:Humans; D016867:Immunocompromised Host; D007866:Leg; D008297:Male; D009164:Mycobacterium Infections / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology / Q000382:microbiology / Q000473:pathology; D018393:Mycobacterium haemophilum / Q000187:drug effects / Q000302:isolation & purification*; D012883:Skin Ulcer / Q000209:etiology; D014946:Wound Infection / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology / Q000382:microbiology
D000900:Anti-Bacterial Agents; D000995:Antitubercular Agents