title: Magnetic resonance imaging findings of adult-onset glutaric aciduria type I.
abstract: Glutaric aciduria or glutaric acidemia type I, an autosomal recessive disease, usually presents with an acute encephalopathic crisis in young children. We report the magnetic resonance (MR) and proton MR spectroscopy (MRS) imaging findings of a previously healthy 20-year-old man who presented with recurrent headaches. Organic acids from the patient's urine contained large amounts of adipate, glutarate, and 3-hydroxyglutarate consistent with glutaric aciduria type I.
authors.affiliation: Department of Radiology, GATA Haydarpasa Teaching Hospital, Istanbul, Turkey.
authors.forename: G
authors.initials: G
authors.lastname: Sonmez
authors.forename: H
authors.initials: H
authors.lastname: Mutlu
authors.forename: E
authors.initials: E
authors.lastname: Ozturk
authors.forename: H O
authors.initials: HO
authors.lastname: Sildiroglu
authors.forename: A T
authors.initials: AT
authors.lastname: Keskin
authors.forename: C C
authors.initials: CC
authors.lastname: Basekim
authors.forename: E
authors.initials: E
authors.lastname: Kizilkaya
mesh_terms: D000272:Adipates / Q000652:urine; D000328:Adult; D000592:Amino Acid Metabolism, Inborn Errors / Q000175:diagnosis*; D005977:Glutarates / Q000378:metabolism* / Q000652:urine; D050770:Glutaryl-CoA Dehydrogenase / Q000172:deficiency*; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D008297:Male
chemical_list: C108959:3-hydroxyglutaric acid; D000272:Adipates; D005977:Glutarates; C029900:adipic acid; D050770:Glutaryl-CoA Dehydrogenase; C035736:glutaric acid