title: [A case of ulcerative colitis relapsed by influenza vaccination].
abstract: Although a large number of studies have reported the causes of the exacerbation of ulcerative colitis (UC), the effect of influenza vaccination on the relapse of UC has not been reported. We experienced a case of prompt exacerbation of quiescent UC due to influenza vaccination. A 39-year-old woman was diagnosed as UC 4-years ago and was well controlled with oral mesalazine. She experienced abdominal pain and frequent bowel movements with hematochezia 3 days after the vaccination. On admission, laboratory findings showed elevated erythrocyte sedimentation rate and C-reactive protein. Sigmoidoscopy showed marked edematous mucosa on rectum and sigmoid colon with fine ulceration and spontaneous bleeding. She recovered from the exacerbation of UC after steroid treatment. Vaccination should be administered to the patients with inflammatory bowel disease with the caution of its possible side effects.
authors.affiliation: Department of Internal Medicine, Eulji University College of Medicine, Eulji Medical Center, Seoul, Korea.
authors.forename: Oh Sung
authors.initials: OS
authors.lastname: Kwon
authors.forename: Young Sook
authors.initials: YS
authors.lastname: Park
authors.forename: Jung Ho
authors.initials: JH
authors.lastname: Choi
authors.forename: Seong Hwan
authors.initials: SH
authors.lastname: Kim
authors.forename: Moon Hee
authors.initials: MH
authors.lastname: Song
authors.forename: Han Hyo
authors.initials: HH
authors.lastname: Lee
authors.forename: Dae Won
authors.initials: DW
authors.lastname: Jeon
authors.forename: Nam In
authors.initials: NI
authors.lastname: Kim
mesh_terms: D000328:Adult; D001799:Blood Sedimentation; D002097:C-Reactive Protein / Q000032:analysis; D003093:Colitis, Ulcerative / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000209:etiology*; D005260:Female; D006801:Humans; D007252:Influenza Vaccines / Q000008:administration & dosage / Q000009:adverse effects*; D012008:Recurrence; D012812:Sigmoidoscopy; D014057:Tomography, X-Ray Computed
chemical_list: D007252:Influenza Vaccines; D002097:C-Reactive Protein