Ileal malignant melanoma causing intussusception: report of a case.
Cutaneous malignant melanoma (MM) often metastasizes to the gastrointestinal (GI) tract; however, primary MM of the small intestine is a controversial diagnosis. We report the case of a 76-year-old woman found to have a primary MM in the ileum. After clinical evaluation, the radiological workup, which included magnetic resonance enteroclysis (MRE), revealed a large polypoid intraluminal tumor. She underwent laparotomy and the lesion was excised. Histological examination of the resected specimen revealed morphological and immunohistochemical characteristics of MM and a detailed postoperative examination failed to identify a primary lesion on the skin, anus, oculus, or any other site. The patient died of brain metastasis 6 months after surgery. According to our review of the literature, this is the first case of primary MM of the small intestine diagnosed with the help of MRE.
Karmiris
Konstantinos
K
Department of Gastroenterology, University Hospital, P.O. Box 1352, 71110, Heraklion, Crete, Greece.
Roussomoustakaki
Maria
M
Tzardi
Maria
M
Romanos
John
J
Grammatikakis
John
J
Papadakis
Manolis
M
Polychronaki
Maria
M
Kouroumalis
Elias A
EA
D000368:Aged; D001932:Brain Neoplasms / Q000556:secondary; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007078:Ileal Neoplasms / Q000150:complications* / Q000473:pathology; D007443:Intussusception / Q000209:etiology*; D008545:Melanoma / Q000150:complications* / Q000473:pathology / Q000556:secondary