title: Survival analysis after surgical treatment of gastric cancer: review of 121 cases.
abstract: OBJECTIVE
  This study was performed to evaluate major morbidity, early mortality and to analyze survival in our patients that underwent surgical treatment for gastric cancer.
  
  
  METHODS
  Records of 121 patients with gastric adenocarcinoma that underwent surgery between 1997 and 2004 were reviewed retrospectively. Age, gender, tumor site, presence of local invasion, depth of tumor invasion, lymph node metastases, stage of the disease, distant metastases, histological differentiation, type of surgery, and blood transfusions were evaluated in relation to survival. Survival curves were estimated using the Kaplan-Meier method and the differences in survival were compared by the log-rank test.
  
  
  RESULTS
  Forty-two cases (34.7%) underwent total gastrectomy, 34 (28.1%) had subtotal gastrectomy, and 45 (37.2%) received palliative surgery. The majority of the patients (61.2%) had stage IV gastric cancer. Total morbidity and mortality were 26.4% and 17.3%, respectively. The factors that influence survival were type of surgery, adjacent organ invasion, existence of metastases, lymph node status, blood transfusions, and stage of the disease in this study. Among the significant prognostic factors in the univariate analysis, only one factor, R0 resection proved to be independently significant in the multivariate analysis.
  
  
  CONCLUSIONS
  R0 resection was found to have a significant favorable effect on survival in our study.
authors.affiliation: Third Surgical Clinic, Atatürk Training and Research Hospital, Izmir, Turkey. okaynazli@hotmail.com
authors.forename: Okay
authors.initials: O
authors.lastname: Nazli
authors.forename: Hayrullah
authors.initials: H
authors.lastname: Derici
authors.forename: Tugrul
authors.initials: T
authors.lastname: Tansug
authors.forename: Ismail
authors.initials: I
authors.lastname: Yaman
authors.forename: Ali Dogan
authors.initials: AD
authors.lastname: Bozdag
authors.forename: Ali Serdar
authors.initials: AS
authors.lastname: Isgüder
authors.forename: Hakan
authors.initials: H
authors.lastname: Bölükbasi
mesh_terms: D000230:Adenocarcinoma / Q000401:mortality* / Q000473:pathology / Q000601:surgery*; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001803:Blood Transfusion; D002423:Cause of Death; D005260:Female; D017052:Hospital Mortality; D006801:Humans; D007902:Length of Stay; D008207:Lymphatic Metastasis / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness / Q000473:pathology; D009367:Neoplasm Staging; D011183:Postoperative Complications / Q000401:mortality*; D011379:Prognosis; D012189:Retrospective Studies; D012307:Risk Factors; D013274:Stomach Neoplasms / Q000401:mortality* / Q000473:pathology / Q000601:surgery*; D016019:Survival Analysis; D014421:Turkey