title: [Relevance of the toxoplasma IgG avidity test in the serological surveillance of pregnant women].
abstract: In addition to the serological systematic screening tests, kits to measure the avidity of toxoplasma IgG antibodies are currently available. Since high-avidity IgG toxoplasma antibodies have been shown to exclude recent infection, IgG avidity determination is especially useful in ruling out acute infection having occurred in the 3-4 prior months of pregnancy. We therefore compared the efficacy of two toxoplasma IgG avidity ELISA kits: SFRI (SFRI Laboratoire) and VIDAS Toxo-IgG avidity kit (bioMérieux). The agreement of the results from the 2 commercial assays were analysed using 55 serum samples, in terms of global mother-child Toxoplasma results and outcome, specially with light of the results of Toxoplasma antenatal, postnatal assays and of clinical follow up of children.
authors.affiliation: Service de parasitologie-mycologie, CHRU de Lille - Faculté de Médecine, Université de Lille 2, and Clinique de gynécologie et obstétrique, Hôpital Jeanne de Flandre, France.
authors.forename: F
authors.initials: F
authors.lastname: Soula
authors.forename: E
authors.initials: E
authors.lastname: Fréalle
authors.forename: I
authors.initials: I
authors.lastname: Durand-Joly
authors.forename: E
authors.initials: E
authors.lastname: Dutoit
authors.forename: V
authors.initials: V
authors.lastname: Rouland
authors.forename: E
authors.initials: E
authors.lastname: Renard
authors.forename: V
authors.initials: V
authors.lastname: Houfflin-Debarge
authors.forename: D
authors.initials: D
authors.lastname: Subtil
authors.forename: D
authors.initials: D
authors.lastname: Camus
authors.forename: E
authors.initials: E
authors.lastname: Dei-Cas
authors.forename: L
authors.initials: L
authors.lastname: Delhaes
mesh_terms: D000818:Animals; D000913:Antibodies, Protozoan / Q000276:immunology*; D000915:Antibody Affinity; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000276:immunology*; D011159:Population Surveillance; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000097:blood*; D011933:Reagent Kits, Diagnostic; D012189:Retrospective Studies; D012698:Serologic Tests / Q000379:methods; D014122:Toxoplasma / Q000276:immunology*; D014123:Toxoplasmosis / Q000097:blood*
chemical_list: D000913:Antibodies, Protozoan; D007074:Immunoglobulin G; D011933:Reagent Kits, Diagnostic