title: Treatment of Morton's neuroma with alcohol injection under sonographic guidance: follow-up of 101 cases.
abstract: OBJECTIVE
  Morton's neuroma is a common cause of forefoot pain. For this study, we assessed the efficacy of a series of sonographically guided alcohol injections into the lesion.
  
  
  METHODS
  One hundred one consecutive patients with Morton's neuroma were included in this prospective series. An average of 4.1 treatments per person were administered, and follow-up images were obtained at a mean of 21.1 months after the last treatment (range, 13-34 months).
  
  
  RESULTS
  Technical success was 100%. Partial or total symptom improvement was reported by 94% of the patients, with 84% becoming totally pain-free. The median visual assessed pain score decreased from 8 before treatment to 0 after treatment (p < 0.001). Transitory increased local pain occurred in 17 cases (16.8%). There were no major complications. Thirty patients underwent sonography at 6 months after the last injection and showed a 30% decrease in the size of the neuroma.
  
  
  CONCLUSIONS
  We conclude that alcohol injection of Morton's neuroma has a high success rate and is well tolerated. The results are at least comparable to surgery, but alcohol injection is associated with less morbidity and surgical management may be reserved for nonresponders.
authors.affiliation: Department of Radiology, Royal National Orthopaedic Hospital and Kingston Hospital NHS Trust, Brockley Hill, Stanmore, Middlesex HA7 4LP, United Kingdom.
authors.forename: Richard J
authors.initials: RJ
authors.lastname: Hughes
authors.forename: Kaline
authors.initials: K
authors.lastname: Ali
authors.forename: Hugh
authors.initials: H
authors.lastname: Jones
authors.forename: Sue
authors.initials: S
authors.lastname: Kendall
authors.forename: David A
authors.initials: DA
authors.lastname: Connell
mesh_terms: D000328:Adult; D000368:Aged; D000431:Ethanol / Q000008:administration & dosage*; D005260:Female; D005500:Follow-Up Studies; D005534:Foot Diseases / Q000000981:diagnostic imaging* / Q000188:drug therapy*; D006801:Humans; D015552:Injections, Intralesional / Q000379:methods; D008297:Male; D008875:Middle Aged; D009463:Neuroma / Q000000981:diagnostic imaging* / Q000188:drug therapy*; D010524:Peripheral Nervous System Neoplasms / Q000000981:diagnostic imaging* / Q000188:drug therapy*; D016896:Treatment Outcome; D014463:Ultrasonography
chemical_list: D000431:Ethanol