title: [Clinical study on 100 cases of severe acute pancreatitis in aged patients].
abstract: OBJECTIVE
  To analyze the clinical features of severe acute pancreatitis (SAP) in aged patients, and to explore the measures of its diagnosis and treatment.
  
  
  METHODS
  The clinical data of 100 aged patients (55-85 years old) with SAP admitted from January 2003 to December 2005 were reviewed and compared with those of 221 non-aged SAP patients (11-54 years old) admitted at the same period.
  
  
  RESULTS
  Totally 112 times of onset occurred in 100 aged patients, and the main causes for senile SAP were biliary diseases and hyperlipemia. Both acute physiology and chronic health evaluation II (APACHE II) and Ranson scores of the aged patients with SAP were higher than those of the control group (P<0.05); while there was no significant difference in Balthazar score between the two groups(P>0.05). The incidences of low serum calcium, low albumin and high aspartate aminotransferase (P<0.05), liver, kidney or brain impairment as well as the mortality were higher in the senile SAP group than those in the control group (P<0.05).
  
  
  CONCLUSIONS
  Biliary disease and hyperlipemia are the main causes of senile SAP, which lacks characteristic clinical symptoms and is often associated with multiple complications such as infection and lung, gastrointestinal tract, liver, kidney, and brain impairment. Individualized differential treatment with integrated traditional Chinese and Western medicine based on stage classification is an effective approach.
authors.affiliation: Department of Integrated Traditional Chinese and Western Medicine, West China Hospital, Sichuan University, Chengdu, Sichuan Province 610041, China.
authors.forename: Wei
authors.initials: W
authors.lastname: Huang
authors.forename: Ping
authors.initials: P
authors.lastname: Xue
authors.forename: Ting-ting
authors.initials: TT
authors.lastname: Liu
authors.forename: Lei
authors.initials: L
authors.lastname: Huang
authors.forename: Da-kai
authors.initials: DK
authors.lastname: Xiang
authors.forename: Lei
authors.initials: L
authors.lastname: Wang
authors.forename: Qing
authors.initials: Q
authors.lastname: Xia
mesh_terms: D018806:APACHE; D000368:Aged; D000369:Aged, 80 and over; D001660:Biliary Tract Diseases / Q000150:complications; D004358:Drug Therapy / Q000379:methods*; D004359:Drug Therapy, Combination; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D006949:Hyperlipidemias / Q000150:complications; D008297:Male; D008875:Middle Aged; D019283:Pancreatitis, Acute Necrotizing / Q000188:drug therapy* / Q000209:etiology; D008517:Phytotherapy / Q000379:methods*; D016896:Treatment Outcome
chemical_list: D004365:Drugs, Chinese Herbal