title: Thirty days complication rate following surgery performed for deep-brain-stimulation.
abstract: Serious adverse events (SAEs) during the first 30 postoperative days after stereotactic surgery for Deep-Brain-Stimulation performed in 1,183 patients were retrospectively collected from five German stereotactic centers. The mortality rate was 0.4% and causes for death were pneumonia, pulmonary embolism, hepatopathy, and a case of complicated multiple sclerosis. The permanent surgical morbidity rate was 1%. The most frequently observed SAEs were intracranial hemorrhage (2.2%) and pneumonia (0.6%). Skin infection occurred in 5 of 1,183 patients (0.4%). Surgical complications caused secondary AEs (e.g. pneumonia) preferentially in older patients and in patients treated for Parkinson's disease (PD). Complication rates did not differ among the five centers.
authors.affiliation: Departments of Neurology and Stereotactic and Functional Neurology, Albertus-Magnus University, Köln, Germany.
authors.forename: Jürgen
authors.initials: J
authors.lastname: Voges
authors.affiliation: Departments of Neurology and Stereotactic and Functional Neurology, Albertus-Magnus University, Köln, Germany.
authors.forename: Rüdiger
authors.initials: R
authors.lastname: Hilker
authors.affiliation: Departments of Neurology and Neurosurgery, Ludwig-Maximilian-University, München, Germany.
authors.forename: Kai
authors.initials: K
authors.lastname: Bötzel
authors.affiliation: Departments of Neurology and Neurosurgery, Ruprecht-Karls University Heidelberg, Germany.
authors.forename: Karl L
authors.initials: KL
authors.lastname: Kiening
authors.affiliation: Departments of Neurology and Neurosurgery, Ruprecht-Karls University Heidelberg, Germany.
authors.forename: Manja
authors.initials: M
authors.lastname: Kloss
authors.affiliation: Departments of Neurology and Neurosurgery, Charite Hospital, Humboldt University Berlin, Germany.
authors.forename: Andreas
authors.initials: A
authors.lastname: Kupsch
authors.affiliation: Department of Neurology, Heinrich-Heine University, Düsseldorf, Germany.
authors.forename: Alfons
authors.initials: A
authors.lastname: Schnitzler
authors.affiliation: Departments of Neurology and Neurosurgery, Charite Hospital, Humboldt University Berlin, Germany.
authors.forename: Gerd-Helge
authors.initials: GH
authors.lastname: Schneider
authors.affiliation: Departments of Neurology and Neurosurgery, Ludwig-Maximilian-University, München, Germany.
authors.forename: Ulrich
authors.initials: U
authors.lastname: Steude
authors.affiliation: Departments of Neurology and Neurosurgery, Christian Albrechts University Kiel, Germany.
authors.forename: Günther
authors.initials: G
authors.lastname: Deuschl
authors.affiliation: Departments of Neurology and Neurosurgery, Christian Albrechts University Kiel, Germany.
authors.forename: Markus O
authors.initials: MO
authors.lastname: Pinsker
mesh_terms: D046690:Deep Brain Stimulation / Q000009:adverse effects*; D004421:Dystonia / Q000601:surgery; D005260:Female; D006801:Humans; D020300:Intracranial Hemorrhages / Q000209:etiology; D008137:Longitudinal Studies; D008297:Male; D011183:Postoperative Complications / Q000209:etiology* / Q000401:mortality / Q000473:pathology / Q000503:physiopathology; D012189:Retrospective Studies; D013997:Time Factors