title: Are large nonfunctional kidneys risk factors for posttransplantation urinary tract infection in patients with end-stage renal disease due to autosomal dominant polycystic kidney disease?
abstract: OBJECTIVE
  The objective of this study was to evaluate the effect of bilateral nephrectomy on posttransplantation urinary tract infection (UTI) among patients with end-stage renal disease (ESRD) due to autosomal dominant polycystic kidney disease (ADPKD).
  
  
  METHODS
  In a retrospective case-control design, 62 patients with ESRD with ADPKD were divided into 2 groups: (A) 24 patients who underwent bilateral nephrectomies, and (B) 38 patients in whom bilateral nephrectomies had not been done. Pretransplantation and posttransplantation urine cultures were evaluated for UTI.
  
  
  RESULTS
  Sixty-two patients with ESRD with ADPKD were enrolled in this study. The average age was 42 years (range, 6-60 years). Forty patients (64.5%) were male and 22 (35.5%) were female. The mean duration of hemodialysis was 24 months (range, 2-120 months), which was the same for both groups. Bilateral nephrectomies were done for 24 participants (38.7%). There were 38 patients (61.3%) in group B who did not have the operation. UTI occurred in 23 patients (37.1%): 6 patients (25%) in group A and 17 patients (44.7%) in group B. The incidence of UTI was not statistically different between the 2 groups (P>.05). Furthermore, no relationship was found between age, gender, blood group, and UTI in patients with ADPKD (P>.05).
  
  
  CONCLUSIONS
  According to our study, the presence of large nonfunctional kidneys is not a risk factor for posttransplantation UTI in patients with ADPKD and ESRD.
authors.affiliation: Shiraz Transplant Center, Nemazee Hospital, Shiraz University of Medical Sciences, Shiraz, Iran. transpln@sums.ac.ir
authors.forename: M
authors.initials: M
authors.lastname: Salehipour
authors.forename: H
authors.initials: H
authors.lastname: Jalaeian
authors.forename: H
authors.initials: H
authors.lastname: Salahi
authors.forename: A
authors.initials: A
authors.lastname: Bahador
authors.forename: H R
authors.initials: HR
authors.lastname: Davari
authors.forename: S
authors.initials: S
authors.lastname: Nikeghbalian
authors.forename: M M
authors.initials: MM
authors.lastname: Sagheb
authors.forename: G A
authors.initials: GA
authors.lastname: Raiss-Jalali
authors.forename: J
authors.initials: J
authors.lastname: Roozbeh
authors.forename: S
authors.initials: S
authors.lastname: Behzadi
authors.forename: P
authors.initials: P
authors.lastname: Janghorban
authors.forename: H N
authors.initials: HN
authors.lastname: Sepas
authors.forename: S A
authors.initials: SA
authors.lastname: Malek-Hosseini
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000209:etiology / Q000601:surgery*; D016030:Kidney Transplantation / Q000009:adverse effects* / Q000592:standards; D008297:Male; D008875:Middle Aged; D016891:Polycystic Kidney, Autosomal Dominant / Q000150:complications; D011183:Postoperative Complications / Q000453:epidemiology; D012307:Risk Factors; D014552:Urinary Tract Infections / Q000453:epidemiology*