[Efficacy of postoperation and the change of red blood cell/hemoglobin in patients with obstructive sleep apnea-hypopnea syndrome].
OBJECTIVE
In order to investigate the effect of UPPP in patients with OSAHS, the range of the soft palate excision and impersonality standard for improving low oxygen after UPPP.


METHODS
A prospective study was designed to evaluate 34 adult patients with OSAHS and 27 adult ear patients who were not OSAHS. Blood routine and palatopharyngeal data in two groups were measured before operation and 15-20 days after operation. And follow up 6 months. The data before and after operation were analysed in statistical method (t test).


RESULTS
Length of soft palate, distance of pharynx, distance of palate pharynx, red blood cell (RBC), hemoglobin (HGB), and hematocrit (HCT) were significantly different in normal and OSAHS group (independent t test, P<0.01). Their indexes were significantly different in OSAHS group before and after operation (paired-sample t test, P<0.01). Only HGB and the lowest SaO2 were negative correlation before operation in OSAHS group. The value is bigger for HGB and smaller for SaO2 (t test, P<0.01). Result of follow up 6 months (31 cases): The effective ratio of subjective improving was 74.2%, and the total effective ratio was 96.8%. One case had reflux of nasopharynx.


CONCLUSIONS
Severe OSAHS patients should be underwent synthesized treatment. It is daytime sleepiness that was improved the most obviously. Soft palate excision scope can't exceed 1.5 cm. HGB can be an impersonality index to assess hypoxemia and improvement of SaO2 after operation for OSAHS.
Wang
Yujing
Y
Department of Otolaryngology, the First Affiliated Hospital of Chinese Medical College, Shenyang, 110001, China. Yujing224109@163.com
Guo
Xing
X
Wang
Yu
Y
Sun
Zhongwu
Z
Hui
Lian
L
D000293:Adolescent; D000328:Adult; D000368:Aged; D016022:Case-Control Studies; D004906:Erythrocyte Count; D004912:Erythrocytes / Q000737:chemistry*; D006454:Hemoglobins / Q000032:analysis*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010160:Palate, Soft / Q000601:surgery; D010614:Pharynx / Q000601:surgery; D011446:Prospective Studies; D020181:Sleep Apnea, Obstructive / Q000097:blood* / Q000601:surgery; D014609:Uvula / Q000601:surgery; D055815:Young Adult
D006454:Hemoglobins