Thirty days complication rate following surgery performed for deep-brain-stimulation.
Serious adverse events (SAEs) during the first 30 postoperative days after stereotactic surgery for Deep-Brain-Stimulation performed in 1,183 patients were retrospectively collected from five German stereotactic centers. The mortality rate was 0.4% and causes for death were pneumonia, pulmonary embolism, hepatopathy, and a case of complicated multiple sclerosis. The permanent surgical morbidity rate was 1%. The most frequently observed SAEs were intracranial hemorrhage (2.2%) and pneumonia (0.6%). Skin infection occurred in 5 of 1,183 patients (0.4%). Surgical complications caused secondary AEs (e.g. pneumonia) preferentially in older patients and in patients treated for Parkinson's disease (PD). Complication rates did not differ among the five centers.
Voges
Jürgen
J
Departments of Neurology and Stereotactic and Functional Neurology, Albertus-Magnus University, Köln, Germany.
Hilker
Rüdiger
R
Departments of Neurology and Stereotactic and Functional Neurology, Albertus-Magnus University, Köln, Germany.
Bötzel
Kai
K
Departments of Neurology and Neurosurgery, Ludwig-Maximilian-University, München, Germany.
Kiening
Karl L
KL
Departments of Neurology and Neurosurgery, Ruprecht-Karls University Heidelberg, Germany.
Kloss
Manja
M
Departments of Neurology and Neurosurgery, Ruprecht-Karls University Heidelberg, Germany.
Kupsch
Andreas
A
Departments of Neurology and Neurosurgery, Charite Hospital, Humboldt University Berlin, Germany.
Schnitzler
Alfons
A
Department of Neurology, Heinrich-Heine University, Düsseldorf, Germany.
Schneider
Gerd-Helge
GH
Departments of Neurology and Neurosurgery, Charite Hospital, Humboldt University Berlin, Germany.
Steude
Ulrich
U
Departments of Neurology and Neurosurgery, Ludwig-Maximilian-University, München, Germany.
Deuschl
Günther
G
Departments of Neurology and Neurosurgery, Christian Albrechts University Kiel, Germany.
Pinsker
Markus O
MO
Departments of Neurology and Neurosurgery, Christian Albrechts University Kiel, Germany.
D046690:Deep Brain Stimulation / Q000009:adverse effects*; D004421:Dystonia / Q000601:surgery; D005260:Female; D006801:Humans; D020300:Intracranial Hemorrhages / Q000209:etiology; D008137:Longitudinal Studies; D008297:Male; D011183:Postoperative Complications / Q000209:etiology* / Q000401:mortality / Q000473:pathology / Q000503:physiopathology; D012189:Retrospective Studies; D013997:Time Factors