title: [A case of successful endoscopic injection sclerotherapy with N-butyl-2-cyanoacrylate for ruptured duodenal varices].
abstract: Duodenal varix is a rare cause of hemorrhage in patients with portal hypertension, however their rupture is serious and often life threatening. Treatments for duodenal variceal bleeding include endoscopic procedures, surgery, or interventional radiologic procedures. We report a case of duodenal varices rupture in a 45-year-old man with alcoholic liver cirrhosis who presented with melena and dizziness. Emergent upper endoscopy revealed large nodular varices with a ruptured erosion on the top in the distal second portion of duodenum. Two consecutive injections with 1.0 mL of n-butyl-2-cyanoacrylate (Histoacryl; Braun-Melsungen, Germany) mixed with 1.0 mL of lipiodol (Laboratoire-Guerbet, France) were performed intravariceally and achieved successful hemostasis. This suggests that endoscopic injection sclerotherapy with histoacryl may be an effective therapeutic option for the control of ruptured duodenal variceal bleeding.
authors.affiliation: Department of Internal Medicine, Hanyang University College of Medicine, Seoul, Korea.
authors.forename: Byoung Kwan
authors.initials: BK
authors.lastname: Son
authors.forename: Joo Hyun
authors.initials: JH
authors.lastname: Sohn
authors.forename: Myung Hee
authors.initials: MH
authors.lastname: Chang
authors.forename: Yoon Kyung
authors.initials: YK
authors.lastname: Park
authors.forename: Tae Yeob
authors.initials: TY
authors.lastname: Kim
authors.forename: Yong Cheol
authors.initials: YC
authors.lastname: Jeon
mesh_terms: D004378:Duodenal Diseases / Q000209:etiology / Q000628:therapy*; D004384:Duodenoscopy; D004386:Duodenum / Q000098:blood supply*; D004659:Enbucrilate / Q000031:analogs & derivatives* / Q000737:chemistry / Q000627:therapeutic use; D006471:Gastrointestinal Hemorrhage / Q000209:etiology / Q000628:therapy*; D006801:Humans; D008104:Liver Cirrhosis, Alcoholic / Q000150:complications; D008297:Male; D008875:Middle Aged; D012421:Rupture; D012597:Sclerosing Solutions / Q000627:therapeutic use*; D015911:Sclerotherapy; D014014:Tissue Adhesives / Q000627:therapeutic use; D014057:Tomography, X-Ray Computed; D014648:Varicose Veins / Q000150:complications / Q000628:therapy*
chemical_list: D012597:Sclerosing Solutions; D014014:Tissue Adhesives; D004659:Enbucrilate