Are patients with hereditary spastic paraplegia different from patients with spastic diplegia during walking? Gait evaluation using 3D gait analysis.
Patients with hereditary spastic paraplegia (HSP) often resemble patients with mild spastic diplegia (SD), although their motor limitations differ. The aim of this study was to analyse quantitatively the gait of HSP and SD subjects in order to define the gait pattern in HSP and the differences between the two conditions. Fifteen subjects with HSP, 40 patients with SD and 20 healthy subjects underwent gait analysis (GA). The spatio-temporal and kinematic parameters at the proximal joints were found to be similar in HSP and SD, whereas the most significant differences were found at the knee and ankle joints. Both groups displayed a tendency for knee hyperextension in the midstance phase, but the duration of this hyperextension was longer in the HSP patients. This study shows that GA complements traditional clinical evaluations, making it possible to distinguish, clearly, between motor ability in HSP and in SD patients; the duration of the knee hyperextension during midstance was found to discriminate between the two gait patterns.
Cimolin
Veronica
V
Department of Bioengineering, Polytechnic of Milan, Italy. veronica.cimolin@polimi.it
Piccinini
Luigi
L
D'Angelo
Maria Grazia
MG
Turconi
Anna Carla
AC
Berti
Matteo
M
Crivellini
Marcello
M
Albertini
Giorgio
G
Galli
Manuela
M
D000293:Adolescent; D000704:Analysis of Variance; D001696:Biomechanical Phenomena / Q000379:methods*; D016022:Case-Control Studies; D002547:Cerebral Palsy / Q000150:complications / Q000175:diagnosis* / Q000503:physiopathology; D002648:Child; D002675:Child, Preschool; D003937:Diagnosis, Differential; D004185:Disability Evaluation; D005684:Gait; D020233:Gait Disorders, Neurologic / Q000145:classification / Q000175:diagnosis* / Q000209:etiology; D006801:Humans; D021621:Imaging, Three-Dimensional / Q000379:methods; D009460:Neurologic Examination; D015419:Spastic Paraplegia, Hereditary / Q000150:complications / Q000175:diagnosis* / Q000503:physiopathology; D016138:Walking