Management of melanoma during pregnancy.
There is no conclusive evidence that pregnancy adversely affects overall survival in patients with melanoma. Clinicians caring for pregnant patients should be as suspicious of changes in melanocytic nevi in these patients as they are for nonpregnant patients. Treatment of early-stage melanoma is the same irrespective of whether or not the patient is pregnant. Chemotherapeutic regimens for metastatic disease administered during pregnancy have not demonstrated significant efficacy.
Leachman
Sancy A
SA
University of Utah Health Sciences Center, Department of Dermatology, and Huntsman Cancer Institute Melanoma Program, University of Utah, Salt Lake City, UT, USA.
Jackson
Ryan
R
Eliason
Mark J
MJ
Larson
April A
AA
Bolognia
Jean L
JL
D000328:Adult; D017677:Age Distribution; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D015984:Causality; D005260:Female; D006801:Humans; D015994:Incidence; D008423:Maternal Age; D008545:Melanoma / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy; D008875:Middle Aged; D009367:Neoplasm Staging / Q000379:methods; D011181:Postnatal Care; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy; D011256:Pregnancy Outcome; D011295:Prenatal Care; D011379:Prognosis; D011446:Prospective Studies; D012189:Retrospective Studies; D012878:Skin Neoplasms / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy; D015996:Survival Rate; D014481:United States / Q000453:epidemiology