[Long QT syndrome induced by cordaron and quinidine].
The article presents an observation of a 63-year-old female patient suffering from arterial hypertension, coronary artery disease complicated by a persistent form of atrial fibrillation during 1.5 months, and hereditary Minkowski-Chauffard hemolytic anemia. Treatment with cordaron proved to be ineffective, while oral administration of quinidin in a dose of 1 gr (0.2 gr five times a day) led to restoration of sinus rhythm. However, long QT interval syndrome complicated by ventricular tachycardic paroxysms of torsade de pointes type developed; later it transformed into ventricular fibrillation.
Mironchik
E V
EV
Dolgosheĭ
T S
TS
Liskovich
T G
TG
Madeshkina
G A
GA
Kokhkovski
A B
AB
Tyshchenko
A D
AD
D000638:Amiodarone / Q000009:adverse effects / Q000627:therapeutic use*; D000743:Anemia, Hemolytic / Q000150:complications; D000889:Anti-Arrhythmia Agents / Q000009:adverse effects*; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000188:drug therapy; D008133:Long QT Syndrome / Q000139:chemically induced* / Q000503:physiopathology; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000150:complications / Q000188:drug therapy; D011802:Quinidine / Q000009:adverse effects*; D016171:Torsades de Pointes / Q000139:chemically induced* / Q000503:physiopathology; D014693:Ventricular Fibrillation / Q000139:chemically induced* / Q000503:physiopathology
D000889:Anti-Arrhythmia Agents; D011802:Quinidine; D000638:Amiodarone