Back to the future--defining NK cells and T cells.
In this issue of the European Journal of Immunology (EJI), Stewart et al. report about a population of gammadelta-T cells expressing an extensive repertoire of NK cell receptors, and the presence of non-rearranged germline TCRdelta transcripts in conventional NK cells. These findings and other recent studies highlight the similarities of NK cells and T cells and the problems in discriminating between these two lineages.
Lanier
Lewis L
LL
Department of Microbiology and Immunology and the Cancer Research Institute, University of California San Francisco, San Francisco, CA 94143-0414, USA. lewis.lanier@ucsf.edu
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