title: [Clinical analysis of 42 extranodal non-Hodgkin's lymphoma originated on head and neck].
abstract: OBJECTIVE
  To analyze clinical features and pathologic classification of extranodal non-Hodgkin's lymphoma (NHL) originated on head and neck and to afford experience in early diagnosis.
  
  
  METHODS
  Retrospective study of clinical material of 42 NHI originated on head and neck, which were proved by pathologic diagnosis.
  
  
  RESULTS
  To divide all the patients into 3 groups according to the position of the disease. There is significant difference of definite diagnosis time between pathological changes in tonsil and nasal cavity (P<0.05). The same result takes place between tonsil and nasal sinuses (P<0.05). There is no significant difference of definite diagnosis time between affection in nasal sinuses and nasal cavity (P>0.05); To divide all the patients into 2 groups according to with or without systematic syndromes, there is no significant difference between the 2 groups (P>0.05).
  
  
  CONCLUSIONS
  The symptoms of extranodal NHL originated in head and neck have no specificity, meanwhile their malignant degree is high. The diagnosis time of affection in tonsil is shorter than that in nasal cavities and nasal sinuses. But with or without systematic syndromes is not related to diagnosis time. Pay attention to unilateral disease in head and neck is important and biopsy is crucial.
authors.affiliation: Department of Otolaryngology, the Third Hospital of Beijing University, Beijing, 100083, China.
authors.forename: Yan
authors.initials: Y
authors.lastname: Yan
authors.forename: Furong
authors.initials: F
authors.lastname: Ma
authors.forename: Li
authors.initials: L
authors.lastname: Wang
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006258:Head and Neck Neoplasms / Q000473:pathology*; D006801:Humans; D008228:Lymphoma, Non-Hodgkin / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D055815:Young Adult