title: Computational protein design: structure, function and combinatorial diversity.
abstract: Computational protein design has blossomed with the development of methods for addressing the complexities involved in specifying the structure, sequence and function of proteins. Recent applications include the design of novel functional membrane and soluble proteins, proteins incorporating non-biological components and protein combinatorial libraries.
authors.affiliation: Department of Chemistry, University of Pennsylvania, 231 South 34th Street, Philadelphia, PA 19104, USA.
authors.forename: Seung-gu
authors.initials: SG
authors.lastname: Kang
authors.forename: Jeffery G
authors.initials: JG
authors.lastname: Saven
mesh_terms: D020650:Combinatorial Chemistry Techniques; D008958:Models, Molecular; D011487:Protein Conformation; D015202:Protein Engineering; D011506:Proteins / Q000737:chemistry* / Q000502:physiology
chemical_list: D011506:Proteins