title: Hypoglycemic activity of Nymphaea stellata leaves ethanolic extract in alloxan induced diabetic rats.
abstract: The ethanolic extract of leaves of Nymphaea stellata given by oral route to diabetic rats at dose of 100 and 200 mg/kg/day for seven days reduced significantly by 31.6 and 42.6 % the plasma glucose level increased by intraperitoneal injection of 120 mg/day of alloxan. Moreover, the treatment significantly affected the plasma level of cholesterol and triglyceride.
authors.affiliation: Department of Pharmacognosy and Pharmacology, J. S. S. College of Pharmacy, Ootacamund, Tamilnadu, India. dhanskanaksahil@rediffmail.com
authors.forename: S P
authors.initials: SP
authors.lastname: Dhanabal
authors.forename: M K Mohan Maruga
authors.initials: MK
authors.lastname: Raja
authors.forename: M
authors.initials: M
authors.lastname: Ramanathan
authors.forename: B
authors.initials: B
authors.lastname: Suresh
mesh_terms: D000284:Administration, Oral; D000496:Alloxan; D000818:Animals; D001786:Blood Glucose / Q000187:drug effects*; D002784:Cholesterol / Q000378:metabolism; D003921:Diabetes Mellitus, Experimental / Q000139:chemically induced / Q000188:drug therapy*; D004305:Dose-Response Relationship, Drug; D007004:Hypoglycemic Agents / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D030721:Nymphaea; D008517:Phytotherapy; D010936:Plant Extracts / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D018515:Plant Leaves; D051381:Rats; D017208:Rats, Wistar; D014280:Triglycerides / Q000378:metabolism
chemical_list: D001786:Blood Glucose; D007004:Hypoglycemic Agents; D010936:Plant Extracts; D014280:Triglycerides; D000496:Alloxan; D002784:Cholesterol