title: Acquired immunodeficiency syndrome related Kaposi's sarcoma eroding the maxillary bone.
abstract: BACKGROUND
  Oral involvement is a common manifestation of acquired immunodeficiency syndrome related Kaposi's sarcoma, and it occurs in approximately one-third of afflicted patients.
  
  
  METHODS
  We report an unusual case of Kaposi's sarcoma of the hard palate which invaded the underlying maxillary bone.
  
  
  RESULTS
  The patient underwent excisional biopsy and was subsequently treated with localised radiation and systemic chemotherapy including liposomal doxorubicin.
  
  
  CONCLUSIONS
  The presentation, differential diagnosis, radiographic appearance and management of this serious complication are discussed. Our case highlights the need for a multidisciplinary approach, consisting of ENT, oncology and infectious disease consultation, to ensure appropriate management of maxillofacial, intraosseous, acquired immunodeficiency syndrome related Kaposi's sarcoma.
authors.affiliation: Division of Hematology Oncology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA.
authors.forename: P A
authors.initials: PA
authors.lastname: Konstantinopoulos
authors.forename: H
authors.initials: H
authors.lastname: Goldsztein
authors.forename: B J
authors.initials: BJ
authors.lastname: Dezube
authors.forename: L
authors.initials: L
authors.lastname: Pantanowitz
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000150:complications*; D006801:Humans; D008297:Male; D008437:Maxilla / Q000473:pathology*; D008875:Middle Aged; D010157:Palatal Neoplasms / Q000473:pathology*; D021362:Palate, Hard / Q000473:pathology*; D012514:Sarcoma, Kaposi / Q000473:pathology*