title: Text mining and protein annotations: the construction and use of protein description sentences.
abstract: Existing biological knowledge stored as structured database records has been extracted manually by database curators analyzing the scientific literature. Most of this information was derived from sentences which describe biologically relevant aspects of genes and gene products. We introduce the Protein description sentence (Prodisen) corpus, a useful resource for the automatic identification and construction of text-based protein and gene description records using information extraction and text classification techniques. Basic guidelines and criteria relevant for the construction of a text corpus of functional descriptions of genes and proteins are proposed. The steps used for the corpus construction and its features are presented. Moreover, some of the potential applications of the Prodisen corpus for biomedical text mining purposes are explored and the obtained results are presented.
authors.affiliation: Dep. Struct. Comp. Biology Spanish National Cancer Centre (CNIO), Melchor Fernández Almagro, 3, E-28029 Madrid, Spain. mkrallinger@cnio.es
authors.forename: Martin
authors.initials: M
authors.lastname: Krallinger
authors.forename: Rainer
authors.initials: R
authors.lastname: Malik
authors.forename: Alfonso
authors.initials: A
authors.lastname: Valencia
mesh_terms: D000043:Abstracting and Indexing; D019295:Computational Biology / Q000379:methods* / Q000592:standards; D003628:Database Management Systems; D030541:Databases, Genetic / Q000145:classification / Q000592:standards*; D016247:Information Storage and Retrieval; D009323:Natural Language Processing; D010363:Pattern Recognition, Automated / Q000379:methods*; D011506:Proteins / Q000737:chemistry / Q000145:classification / Q000235:genetics*
chemical_list: D011506:Proteins