title: Regional cerebral blood flow after recovery from anorexia or bulimia nervosa.
abstract: OBJECTIVE
  Abnormalities of regional cerebral blood flow (rCBF) have been found in individuals who are ill with anorexia (AN) or bulimia nervosa (BN). Little is known about whether rCBF normalizes after recovery from AN and BN.
  
  
  METHODS
  Eighteen control women (CW), 10 recovered restricting type AN, 8 recovered AN with a binging history, and 9 recovered BN participants without a history of AN were studied using positron emission tomography and [(15)O]water in order to assess rCBF.
  
  
  RESULTS
  Partial volume corrected rCBF values in cortical and subcortical brain regions were similar between groups. Neither current body mass index nor age correlated with rCBF values.
  
  
  CONCLUSIONS
  The results from this study indicate that rCBF normalizes with long-term recovery. Thus, altered rCBF is unlikely to confound functional imaging studies in AN or BN after recovery.
authors.affiliation: Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA.
authors.forename: Guido K
authors.initials: GK
authors.lastname: Frank
authors.forename: Ursula F
authors.initials: UF
authors.lastname: Bailer
authors.forename: Carolyn C
authors.initials: CC
authors.lastname: Meltzer
authors.forename: Julie C
authors.initials: JC
authors.lastname: Price
authors.forename: Chester A
authors.initials: CA
authors.lastname: Mathis
authors.forename: Angela
authors.initials: A
authors.lastname: Wagner
authors.forename: Carl
authors.initials: C
authors.lastname: Becker
authors.forename: Walter H
authors.initials: WH
authors.lastname: Kaye
mesh_terms: D000328:Adult; D000855:Anorexia / Q000503:physiopathology* / Q000628:therapy*; D015992:Body Mass Index; D001921:Brain / Q000033:anatomy & histology / Q000098:blood supply* / Q000503:physiopathology*; D052018:Bulimia Nervosa / Q000503:physiopathology* / Q000628:therapy*; D002560:Cerebrovascular Circulation / Q000502:physiology; D006801:Humans; D008279:Magnetic Resonance Imaging; D049268:Positron-Emission Tomography; D020127:Recovery of Function