Functional characterization of Streptomyces coelicolor FtsY.
This study indicated that the N-terminus was dispensable for FtsY GTPase activity, and that the N-domain plays an essential role in the GTPase activity of the NG domain. In addition, the S.scoelicolor FtsY was able to restore function in an E. coli mutant. However, its NG domain was unable to play any roles.
Dong
Hui-Jun
HJ
Zhejiang University College of Life Science, Hangzhou, PR China.
Shen
Xue-Ling
XL
Li
Yu-Dong
YD
Li
Yong-Quan
YQ
D001426:Bacterial Proteins / Q000737:chemistry* / Q000378:metabolism; D004926:Escherichia coli / Q000378:metabolism; D020558:GTP Phosphohydrolases / Q000378:metabolism*; D006863:Hydrogen-Ion Concentration; D057927:Hydrophobic and Hydrophilic Interactions; D008274:Magnesium / Q000494:pharmacology; D017434:Protein Structure, Tertiary; D018160:Receptors, Cytoplasmic and Nuclear / Q000737:chemistry* / Q000378:metabolism; D048372:Streptomyces coelicolor / Q000737:chemistry*; D013696:Temperature
D001426:Bacterial Proteins; C087406:FtsY protein, Bacteria; D018160:Receptors, Cytoplasmic and Nuclear; D020558:GTP Phosphohydrolases; D008274:Magnesium