The value of serum tau protein for the diagnosis of intracranial injury in minor head trauma.
OBJECTIVE
Tau protein localizes in the axons of neuron cells, and it is released secondarily from the central nervous system because of hypoxia and trauma. In the present study, it was aimed to investigate the value of serum tau protein levels in diagnosing intracranial pathologies in minor head trauma.


METHODS
Patients were categorized into 2 groups: those without intracranial lesions in head CTs (group 1) and those with lesions in head CTs (group 2). Serum tau protein levels were determined.


RESULTS
Group 1 (n = 55) median serum tau protein level was 16.29 pg/mL (2.12-215.97 pg/mL) and group 2 (n = 33) median serum tau protein level was 18.39 pg/mL (2.19-714.47 pg/mL). Statistical analysis revealed no significant difference between the 2 groups for tau protein values, sex, age, mechanism of trauma, and Glasgow Coma Scale score.


CONCLUSIONS
It is suggested that serum tau protein has limited value in minor head trauma.
Kavalci
Cemil
C
Department of Emergency Medicine, Firat University Faculty of Medicine, Elaziğ, Turkey.
Pekdemir
Murat
M
Durukan
Polat
P
Ilhan
Necip
N
Yildiz
Mustafa
M
Serhatlioglu
Selami
S
Seckin
Dilara
D
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D015415:Biomarkers / Q000097:blood; D002648:Child; D002675:Child, Preschool; D006259:Craniocerebral Trauma / Q000097:blood* / Q000175:diagnosis*; D003430:Cross-Sectional Studies; D005260:Female; D015600:Glasgow Coma Scale; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012044:Regression Analysis; D012680:Sensitivity and Specificity; D012737:Sex Factors; D016875:tau Proteins / Q000097:blood*
D015415:Biomarkers; D016875:tau Proteins