title: Catalytic enantioselective Friedel-Crafts alkylations of indoles with alpha'-phosphoric enones.
abstract: The C2-symmetric bis(oxazoline) copper(II) complex proves to be an excellent catalyst in the Friedel-Crafts alkylation of indoles with alpha'-phosphoric enones. The enantioselectivities of this reaction are obtained in up to 98% ee.
authors.affiliation: Center for Molecular Design & Synthesis and Department of Chemistry, School of Molecular Science, Korea Advanced Institute of Science and Technology, Daejeon 305-701, Korea.
authors.forename: Hyeyeon
authors.initials: H
authors.lastname: Yang
authors.forename: Young-Taek
authors.initials: YT
authors.lastname: Hong
authors.forename: Sunggak
authors.initials: S
authors.lastname: Kim
mesh_terms: D000478:Alkylation; D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D007211:Indoles / Q000138:chemical synthesis* / Q000737:chemistry*; D007659:Ketones / Q000737:chemistry*; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D063065:Organophosphonates / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D007211:Indoles; D007659:Ketones; D009942:Organometallic Compounds; D063065:Organophosphonates; D003300:Copper