Angiotensin-converting enzyme inhibition by Brazilian plants.
The potential antihypertensive activity of Brazilian plants was evaluated in vitro by its ability to inhibit the angiotensin-converting enzyme (ACE). Forty-four plants belonging to 30 families were investigated. Plants were selected based on their popular use as antihypertensive and/or diuretics. The following plants presented significant ACE inhibition rates: Calophyllum brasiliense, Combretum fruticosum, Leea rubra, Phoenix roebelinii and Terminalia catappa.
Braga
Fernão C
FC
Faculdade de Farmácia, Universidade Federal de Minas Gerais, Av. Antônio Carlos, Belo Horizonte, Brazil. fernao@netuno.lcc.ufmg.br
Serra
Carla P
CP
Viana
Nilton S
NS
Oliveira
Alaíde B
AB
Côrtes
Steyner F
SF
Lombardi
Júlio A
JA
D000806:Angiotensin-Converting Enzyme Inhibitors / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D001938:Brazil; D029759:Calophyllum; D029765:Combretum; D006801:Humans; D008519:Medicine, Traditional; D008517:Phytotherapy; D035261:Plant Components, Aerial; D010936:Plant Extracts / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D018515:Plant Leaves; D018547:Plant Stems; D010946:Plants, Medicinal; D029766:Terminalia
D000806:Angiotensin-Converting Enzyme Inhibitors; D010936:Plant Extracts