Exuberant molluscum contagiosum as a manifestation of the immune reconstitution inflammatory syndrome.
Immune reconstitution inflammatory syndrome (IRIS) is a recently described entity in which severely immunodepressed HIV patients, after being started on HAART, develop inflammatory reactions to several pathogens. We present a patient who developed extensive Molluscum Contagiosum (MC) lesions shortly after being started on HAART. With the progression of immunoreconstitution, the lesions healed spontaneously. Molluscum contagiosum lesions are presumably common in IRIS but underreported. We point out this case for its striking clinical picture and well-documented relation to immunoreconstitution to draw attention to this IRIS manifestation.
Pereira
Bárbara
B
Hospital de Curry Cabral, Dermatology Department, Lisbon, Portugal. barbararosa@hotmail.com
Fernandes
Cândida
C
Nachiambo
Ermelinda
E
Catarino
Ma Carmo
MC
Rodrigues
Ana
A
Cardoso
Jorge
J
D000368:Aged; D023241:Antiretroviral Therapy, Highly Active / Q000009:adverse effects* / Q000379:methods; D005500:Follow-Up Studies; D015658:HIV Infections / Q000175:diagnosis / Q000188:drug therapy* / Q000276:immunology; D006681:HLA-D Antigens / Q000276:immunology*; D006801:Humans; D007108:Immune Tolerance; D016867:Immunocompromised Host; D007249:Inflammation / Q000276:immunology* / Q000503:physiopathology / Q000628:therapy; D008297:Male; D008976:Molluscum Contagiosum / Q000139:chemically induced / Q000276:immunology* / Q000628:therapy; D018570:Risk Assessment; D012720:Severity of Illness Index; D013577:Syndrome; D019562:Viral Load
D006681:HLA-D Antigens