title: Zinc intoxication in dogs: 19 cases (1991-2003).
abstract: OBJECTIVE
  To determine physical examination findings, clinicopathologic changes, and prognosis in dogs with zinc toxicosis.
  
  
  METHODS
  Retrospective case series.
  
  
  METHODS
  19 dogs with zinc toxicosis.
  
  
  METHODS
  Medical records from 1991 through 2003 were searched for animals with a diagnosis of zinc toxicosis. Information concerning signalment, body weight, historical findings, initial owner complaints, physical examination findings, clinicopathologic findings, blood zinc concentrations, source of zinc, treatments given, duration of hospital stay, and outcome was collected.
  
  
  RESULTS
  Records of 19 dogs with zinc toxicosis were reviewed. The most common historical findings were vomiting (n = 14) and pigmenturia (12). The most common clinicopathologic findings were anemia (n = 19) and hyperbilirubinemia (12). Median age was 1.3 years, and median weight was 5.6 kg (12.3 lb). The prognosis was favorable, with 17 dogs surviving after a median hospital stay of 2 days.
  
  
  CONCLUSIONS
  Hemolytic anemia as a result of zinc toxicosis appeared to affect young small-breed dogs more frequently than older large-breed dogs. The prognosis with treatment is good, and most affected dogs had a short hospital stay.
authors.affiliation: Matthew J. Ryan Veterinary Hospital, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104-5438, USA.
authors.forename: Carolyn M
authors.initials: CM
authors.lastname: Gurnee
authors.forename: Kenneth J
authors.initials: KJ
authors.lastname: Drobatz
mesh_terms: D000367:Age Factors; D000743:Anemia, Hemolytic / Q000139:chemically induced / Q000453:epidemiology / Q000662:veterinary*; D000818:Animals; D004283:Dog Diseases / Q000139:chemically induced* / Q000453:epidemiology / Q000601:surgery; D004285:Dogs; D005260:Female; D005547:Foreign Bodies / Q000662:veterinary; D006932:Hyperbilirubinemia / Q000139:chemically induced / Q000662:veterinary; D007902:Length of Stay; D008297:Male; D011041:Poisoning / Q000453:epidemiology / Q000601:surgery / Q000662:veterinary*; D011379:Prognosis; D012189:Retrospective Studies; D014131:Trace Elements / Q000506:poisoning*; D016896:Treatment Outcome; D014481:United States; D014839:Vomiting / Q000139:chemically induced / Q000662:veterinary; D015032:Zinc / Q000506:poisoning*
chemical_list: D014131:Trace Elements; D015032:Zinc