Temporal lobe dual pathology in malignant migrating partial seizures in infancy.
A child had the characteristic clinical and EEG pattern of migrating partial seizures in infancy with left temporal lobe atrophy, hippocampal sclerosis and cortical-subcortical blurring. Seizures were drug-resistant, with recurring episodes of status epilepticus. The child developed microcephaly with arrest of psychomotor development. Focal brain lesions, in the context of migrating partial seizures, have not been previously reported.[Published with video sequences].
Coppola
Giangennaro
G
Clinic of Child and Adolescent Psychiatry, Second University of Naples. giangennaro.coppola@unina2.it
Operto
Francesca Felicia
FF
Auricchio
Gianfranca
G
D'Amico
Alessandra
A
Fortunato
Delia
D
Pascotto
Antonio
A
D001284:Atrophy / Q000473:pathology; D001927:Brain Diseases / Q000175:diagnosis* / Q000453:epidemiology; D002675:Child, Preschool; D015897:Comorbidity; D004569:Electroencephalography / Q000706:statistics & numerical data; D004828:Epilepsies, Partial / Q000175:diagnosis* / Q000453:epidemiology; D004833:Epilepsy, Temporal Lobe / Q000453:epidemiology / Q000473:pathology; D005260:Female; D007839:Functional Laterality; D006624:Hippocampus / Q000473:pathology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008831:Microcephaly / Q000453:epidemiology*; D011596:Psychomotor Disorders / Q000453:epidemiology / Q000473:pathology; D012598:Sclerosis / Q000473:pathology; D013226:Status Epilepticus / Q000175:diagnosis / Q000453:epidemiology; D013702:Temporal Lobe / Q000473:pathology*