title: A FAScinating receptor in self-tolerance.
abstract: In this issue of Immunity,Stranges et al. (2007) ablate expression of the death receptor Fas in T cells, B cells, and DC. Fas deficiency in any of these lineages is sufficient to break self-tolerance.
authors.affiliation: Immunoregulation Unit, Autoimmunity Branch, NIAMS, National Institutes of Health, Bethesda, MD 20892, USA.
authors.forename: Madhu
authors.initials: M
authors.lastname: Ramaswamy
authors.forename: Richard M
authors.initials: RM
authors.lastname: Siegel
mesh_terms: D000818:Animals; D017951:Antigen Presentation / Q000276:immunology; D016923:Cell Death; D006801:Humans; D017634:Self Tolerance / Q000276:immunology*; D019014:fas Receptor / Q000276:immunology*
chemical_list: D019014:fas Receptor