title: Fawcettimine-related alkaloids from Lycopodium serratum.
abstract: Five new Lycopodium alkaloids (1-5) having the fawcettimine skeleton were isolated from Lycopodium serratum. The structures of the alkaloids were elucidated on the basis of spectroscopic analysis. Some alkaloids isolated in this and previous studies (1, 2, 5, and 10) were assayed for acetylcholine esterase (AChE) inhibitory activity.
authors.affiliation: Graduate School of Pharmaceutical Sciences, Chiba University, 1-33 Yayoi-cho, Inage-ku, Chiba 263-8522, Japan.
authors.forename: Kazuaki
authors.initials: K
authors.lastname: Katakawa
authors.forename: Akiko
authors.initials: A
authors.lastname: Nozoe
authors.forename: Noriyuki
authors.initials: N
authors.lastname: Kogure
authors.forename: Mariko
authors.initials: M
authors.lastname: Kitajima
authors.forename: Masakiyo
authors.initials: M
authors.lastname: Hosokawa
authors.forename: Hiromitsu
authors.initials: H
authors.lastname: Takayama
mesh_terms: D000470:Alkaloids / Q000737:chemistry* / Q000302:isolation & purification* / Q000494:pharmacology; D002800:Cholinesterase Inhibitors / Q000737:chemistry* / Q000302:isolation & purification* / Q000494:pharmacology; D006576:Heterocyclic Compounds, 4 or More Rings / Q000737:chemistry* / Q000302:isolation & purification* / Q000494:pharmacology; D007564:Japan; D032502:Lycopodium / Q000737:chemistry*; D015394:Molecular Structure; D010946:Plants, Medicinal / Q000737:chemistry*
chemical_list: D000470:Alkaloids; D002800:Cholinesterase Inhibitors; D006576:Heterocyclic Compounds, 4 or More Rings