Novel complex class 1 integron bearing an ISCR1 element in an Escherichia coli isolate carrying the blaCTX-M-14 gene.
This work identifies an ISCR1-related bla(CTX-M-14) gene, which has never been reported before, from a clinical isolate of Escherichia coli. The bla(CTX-M-14) gene was preceded by an ISCR1 element that was followed by a class 1 integron containing three different insert gene cassettes, i.e., dfrA12, orfF, and aadA2.
Bae
Il Kwon
IK
Research Institute for Antimicrobial Resistance and Department of Laboratory Medicine, Kosin University College of Medicine, 34 Amnam-Dong, Suh-Gu, Busan, Republic of Korea.
Lee
You-Nae
YN
Lee
Wee Gyo
WG
Lee
Sang Hee
SH
Jeong
Seok Hoon
SH
D000328:Adult; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D001483:Base Sequence; D004251:DNA Transposable Elements / Q000235:genetics*; D024881:Drug Resistance, Bacterial / Q000235:genetics*; D004926:Escherichia coli / Q000187:drug effects / Q000201:enzymology* / Q000235:genetics / Q000302:isolation & purification; D004927:Escherichia coli Infections / Q000382:microbiology; D029968:Escherichia coli Proteins / Q000235:genetics / Q000378:metabolism; D006801:Humans; D032023:Integrons / Q000235:genetics*; D008297:Male; D008826:Microbial Sensitivity Tests; D008969:Molecular Sequence Data; D018410:Pneumonia, Bacterial / Q000382:microbiology; D017422:Sequence Analysis, DNA; D001618:beta-Lactamases / Q000235:genetics / Q000378:metabolism
D000900:Anti-Bacterial Agents; D004251:DNA Transposable Elements; D029968:Escherichia coli Proteins; C456080:beta-lactamase CTX-M-14; D001618:beta-Lactamases