title: Tetrodotoxin and its analogue 6-epitetrodotoxin in newts (Triturus spp.; Urodela, Salamandridae) from southern Germany.
abstract: Tetrodotoxin (TTX) and its analogue 6-epitetrodotoxin (6-epiTTX) were quantitatively assayed in 59 newts representing four Triturus species (Triturus alpestris, Triturus cristatus, Triturus helveticus, Triturus vulgaris) from southern Germany by a post-column fluorescent-HPLC system. Both toxins were detected in only 15 specimens of the four species. The toxins levels varied considerably among individuals (TTX: 0.11-9.0microg/g; 6-epiTTX: 0.05-17.0microg/g). 6-epiTTX was found to be the major component.
authors.affiliation: Graduate School of Agricultural Science, Tohoku University, 1-1 Tsutsumidori-Amamiyamachi, Aoba-ku, Sendai 981-8555, Japan.
authors.forename: Mari
authors.initials: M
authors.lastname: Yotsu-Yamashita
authors.forename: Dietrich
authors.initials: D
authors.lastname: Mebs
authors.forename: Axel
authors.initials: A
authors.lastname: Kwet
authors.forename: Michael
authors.initials: M
authors.lastname: Schneider
mesh_terms: D000818:Animals; D002851:Chromatography, High Pressure Liquid; D005858:Germany; D013045:Species Specificity; D013779:Tetrodotoxin / Q000032:analysis* / Q000633:toxicity; D014562:Caudata / Q000378:metabolism*
chemical_list: C076431:6-epitetrodotoxin; D013779:Tetrodotoxin