title: Percentage non-caeruloplasmin bound copper.
abstract: OBJECTIVE
  To compare percentage non-caeruloplasmin bound copper (%NCC) to generally accepted values.
  
  
  METHODS
  Using data for 338 normal individual patients, we calculated the %NCC.
  
  
  RESULTS
  The %NCC ranged (median) from -59.75% to 51.98% (8.75%) respectively. The non-parametric reference interval was -23.44% to 22.99% with 43.8% of the %NCC values >10%.
  
  
  CONCLUSIONS
  We found the %NCC to be higher than generally accepted. This may be due to uncertainty from precision, bias and specificity.
authors.affiliation: Department of Clinical Biochemistry, The Ipswich Hospital, Heath Road, Ipswich IP4 5PD, UK. patrick.twomey@ipswichhospital.nhs.uk
authors.forename: Patrick J
authors.initials: PJ
authors.lastname: Twomey
authors.forename: Anthony S
authors.initials: AS
authors.lastname: Wierzbicki
authors.forename: Ivan M
authors.initials: IM
authors.lastname: House
authors.forename: Adie
authors.initials: A
authors.lastname: Viljoen
authors.forename: Timothy M
authors.initials: TM
authors.lastname: Reynolds
mesh_terms: D002570:Ceruloplasmin / Q000032:analysis*; D003300:Copper / Q000097:blood*; D006801:Humans; D011485:Protein Binding; D012016:Reference Values
chemical_list: D003300:Copper; D002570:Ceruloplasmin