Putting the fizz into chemistry: applications of supercritical carbon dioxide in tissue engineering, drug delivery and synthesis of novel block copolymers.
This paper describes the recent progress at Nottingham towards the exploitation of the unique properties of scCO(2) (supercritical carbon dioxide) for the preparation of polymeric scaffolds for tissue engineering applications and new devices for controlled drug delivery, as well as the synthesis of novel block copolymers by the combination of eROP (enzymatic ring opening polymerization) and controlled polymerization methods for the potential use as drug carriers.
Tai
H
H
Clean Technology Group, School of Chemistry, University of Nottingham, University Park, Nottingham NG 7 2RD, UK.
Popov
V K
VK
Shakesheff
K M
KM
Howdle
S M
SM
D000818:Animals; D001672:Biocompatible Materials / Q000138:chemical synthesis; D002245:Carbon Dioxide / Q000737:chemistry*; D002460:Cell Line; D016503:Drug Delivery Systems; D008422:Materials Testing; D051379:Mice; D011108:Polymers / Q000138:chemical synthesis*; D011312:Pressure; D013696:Temperature; D023822:Tissue Engineering / Q000379:methods*
D001672:Biocompatible Materials; D011108:Polymers; D002245:Carbon Dioxide