title: Infectious crystalline keratopathy caused by Gemella haemolysans.
abstract: OBJECTIVE
  To report a novel case of infectious crystalline keratopathy after penetrating keratoplasty caused by Gemella haemolysans.
  
  
  METHODS
  Observational case report. Patient notes and literature review.
  
  
  RESULTS
  A 51-year-old woman presented with the clinical picture of infectious crystalline keratopathy 18 months after a second penetrating keratoplasty was performed for corneal decompensation secondary to recurrent herpes simplex infection. Corneal biopsy yielded a heavy growth of G. haemolysans. Initial treatment was made up of frequent topical vancomycin 0.5% and was later changed to topical cefuroxime 5% and ofloxacin 0.3%. Snellen visual acuity after complete resolution of the keratitis was 6/60 as a result of a residual corneal scar.
  
  
  CONCLUSIONS
  Gemella haemolysans may be an etiologic agent in infectious crystalline keratopathy. A corneal biopsy may be diagnostic but may also promote healing by allowing direct access of antibiotics to deep-seated infected tissue and by altering the growth environment of the organism.
authors.affiliation: Southampton University Hospitals Trust, Southampton, Hampshire, UK.
authors.forename: Anusha
authors.initials: A
authors.lastname: Kailasanathan
authors.forename: David F
authors.initials: DF
authors.lastname: Anderson
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002444:Cefuroxime / Q000627:therapeutic use; D015169:Colony Count, Microbial; D003316:Corneal Diseases / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D004359:Drug Therapy, Combination; D015818:Eye Infections, Bacterial / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D005260:Female; D016908:Gram-Positive Bacterial Infections / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D006801:Humans; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D015242:Ofloxacin / Q000627:therapeutic use; D040141:Staphylococcaceae / Q000187:drug effects / Q000302:isolation & purification*
chemical_list: D000900:Anti-Bacterial Agents; D015242:Ofloxacin; D002444:Cefuroxime