[The correlation between ultrastructure of lymphatic capillary and neck lymph node metastasis laryngeal carcinoma].
OBJECTIVE
To study the correlation between ultrastructure of lymphatic capillary in pericancerous tissue and neck lymph node metastasis in laryngeal carcinoma.


METHODS
Transmission electronic microscope was applied to observe and compare ultrastructure of lymphatic capillary in 8 normal laryngeal epithelial tissue and 12 pericancerous tissue of laryngeal cancer.


RESULTS
Lymphatic capillary of pericancerous tissue was significantly dilated compared with normal laryngeal tissue. A large amount of endothelial cell junction was open and devoid of basement membrane. Some endothelial cells of lymphatic capillary were destroyed or broken completely.


CONCLUSIONS
Ultrastructure of lymphatic capillary in pericancerous tissue is an important factor of laryngeal cancer metastasis through lymphatic system. This research offers theoretic basis for laryngeal carcinoma metastasis mechanism and prevention.
Li
Ye
Y
Department of Otorhinolaryngology, the Second Hospital of Jilin University, Changchun, China.
Xin
Ding
D
Wen
Lianji
L
Jin
Chunshun
C
D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000473:pathology*; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D007820:Laryngeal Mucosa / Q000473:pathology; D007822:Laryngeal Neoplasms / Q000473:pathology*; D008198:Lymph Nodes / Q000473:pathology; D008207:Lymphatic Metastasis; D042601:Lymphatic Vessels / Q000473:pathology* / Q000648:ultrastructure*; D008297:Male; D046529:Microscopy, Electron, Transmission; D008875:Middle Aged; D009333:Neck; D009367:Neoplasm Staging