title: Managing multiple and extensively drug-resistant tuberculosis and HIV.
abstract: Global increases in multi-drug-resistant and extensively drug-resistant tuberculosis (TB), are threatening both TB and HIV treatment programs worldwide. Together, they raise concerns of a global epidemic of untreatable TB. In the developing world, the directly observed treatment, short course (DOTS) strategy is proving ineffective as available resources are being outstripped by the large number of patients needing treatment. Thus, TB treatment and outcomes are sub-optimal, and multi-drug resistant and extensively drug-resistant TB are on the rise.
authors.forename: Nesri
authors.initials: N
authors.lastname: Padayatchi
authors.forename: Gerald
authors.initials: G
authors.lastname: Friedland
mesh_terms: D019380:Anti-HIV Agents / Q000627:therapeutic use; D000995:Antitubercular Agents / Q000627:therapeutic use*; D003906:Developing Countries; D023801:Directly Observed Therapy; D004196:Disease Outbreaks; D024881:Drug Resistance, Bacterial; D018432:Drug Resistance, Multiple; D014943:Global Health; D015658:HIV Infections / Q000150:complications / Q000188:drug therapy* / Q000453:epidemiology; D006282:Health Personnel; D006801:Humans; D015995:Prevalence; D016896:Treatment Outcome; D018088:Tuberculosis, Multidrug-Resistant / Q000150:complications / Q000188:drug therapy* / Q000453:epidemiology
chemical_list: D019380:Anti-HIV Agents; D000995:Antitubercular Agents