Epidermotropic metastatic prostate carcinoma presenting as an umbilical nodule-Sister Mary Joseph nodule.
Carcinoma of the prostate accounts for fewer than 1% of all skin metastases. Cutaneous metastases from prostate carcinoma most often involve the penis, the anterior aspect of the thighs, the suprapubic area, and the perineum, but they also have been reported in the scalp, the chest, the back, and even the face. We report an unusual case of metastatic prostate adenocarcinoma that presented as an umbilical nodule (Sister Mary Joseph nodule) and demonstrated significant epidermotropism histologically. A review of the literature has found only one documented case of prostatic carcinoma metastasizing to the umbilicus, and one other documented case of epidermotropic metastatic prostate carcinoma.
Stanko
Christine
C
Department of Dermatology, Drexel University College of Medicine, Philadelphia, PA, USA. cstanko123@hotmail.com
Grandinetti
Lisa
L
Baldassano
Marisa
M
Mahmoodi
Mandana
M
Kantor
Gary R
GR
D000230:Adenocarcinoma / Q000556:secondary*; D000369:Aged, 80 and over; D006801:Humans; D008297:Male; D011471:Prostatic Neoplasms / Q000473:pathology*; D012878:Skin Neoplasms / Q000556:secondary*; D014472:Umbilicus / Q000473:pathology*