title: The implications of ISAT and ISUIA for the management of cerebral aneurysms during pregnancy.
abstract: Both the International Subarachnoid Aneurysm Trial (ISAT) and the International Study on Unruptured Intracranial Aneurysms (ISUIA) have been widely extrapolated to influence the management of actual or anticipated aneurysmal subarachnoid hemorrhage (SAH). However, it remains possible that sub-groups exist for which such extrapolation might subsequently prove premature. In this review, we discuss the implications that such extrapolation may potentially have for one such SAH sub-group: the clinically rare scenario of SAH in pregnancy.
authors.affiliation: Departments of Neurosurgery, Oldchurch Hospital, Waterloo Rd Romford, Essex, RM7 0BE, UK. l.a.g.marshman@btinternet.com
authors.forename: Laurence A G
authors.initials: LA
authors.lastname: Marshman
authors.forename: A Robert
authors.initials: AR
authors.lastname: Aspoas
authors.forename: Manjit S
authors.initials: MS
authors.lastname: Rai
authors.forename: Sanjiv J
authors.initials: SJ
authors.lastname: Chawda
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D002532:Intracranial Aneurysm / Q000601:surgery / Q000628:therapy*; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000601:surgery / Q000628:therapy*; D016634:Radiosurgery; D013345:Subarachnoid Hemorrhage / Q000601:surgery / Q000628:therapy*