The impact of uterine artery embolization on fertility and pregnancy outcome.
OBJECTIVE
Uterine artery embolization for management of symptomatic fibroids is an effective and increasingly popular treatment option. There are several studies evaluating the effects of uterine artery embolization on later pregnancies; however, the effects on fertility are still largely uncertain. This paper reviews the current literature on the effects of this technique on fertility and pregnancy outcome.


RESULTS
Two recent studies have reported pregnancy rates following uterine artery embolization in women seeking pregnancy. A small, third study reported preliminary results in a randomized controlled trial comparing uterine artery embolization with myomectomy in women wishing to preserve fertility.


CONCLUSIONS
The body of medical literature supports use of uterine artery embolization as an effective treatment for symptoms of vaginal bleeding and pelvic pressure from uterine fibroids. Patient selection is critical in determining the appropriateness of this treatment option. Myomectomy remains the standard of care for women with symptomatic fibroids seeking fertility preservation.
Usadi
Rebecca S
RS
Division of Reproductive Endocrinology and Infertility, Carolinas Medical Center, Charlotte, North Carolina 28232-2861, USA. rebecca.usadi@carolinashealthcare.org
Marshburn
Paul B
PB
D000792:Angiography; D001158:Arteries; D004621:Embolization, Therapeutic / Q000009:adverse effects / Q000379:methods*; D004624:Embryo Transfer; D005260:Female; D005298:Fertility; D006801:Humans; D007889:Leiomyoma / Q000150:complications / Q000628:therapy*; D011247:Pregnancy; D011256:Pregnancy Outcome; D011379:Prognosis; D012307:Risk Factors; D014599:Uterus / Q000098:blood supply*