Prosthetic valve endocarditis due to Neisseria elongata subsp. elongata in a patient with Klinefelter's syndrome.
A case is reported of prosthetic valve endocarditis due to Neisseria elongata subsp. elongata in a patient with Klinefelter's syndrome. This is believed to be only the third case of endocarditis reported due to this subspecies. N. elongata is difficult to identify, and is morphologically and biochemically similar to Kingella spp. Sequencing of the 16S rRNA gene is useful for identification. The patient was successfully treated with amoxicillin and gentamicin, followed by ceftriaxone.
Evans
Morgan
M
Department of Clinical Microbiology, Nottingham University Hospitals NHS Trust, Queen's Medical Centre, Nottingham NG7 2UH, UK.
Yazdani
Farah
F
Department of Clinical Microbiology, Nottingham University Hospitals NHS Trust, Queen's Medical Centre, Nottingham NG7 2UH, UK.
Malnick
Henry
H
Laboratory of HealthCare Associated Infection, Centre for Infections, Health Protection Agency, Colindale, London, UK.
Shah
Jayesh J
JJ
Laboratory of HealthCare Associated Infection, Centre for Infections, Health Protection Agency, Colindale, London, UK.
Turner
David P J
DPJ
Institute of Infections, Immunity and Inflammation, School of Molecular Medical Sciences, Centre for Biomolecular Sciences, University of Nottingham, Nottingham, UK.|Department of Clinical Microbiology, Nottingham University Hospitals NHS Trust, Queen's Medical Centre, Nottingham NG7 2UH, UK.
D000368:Aged; D000658:Amoxicillin / Q000008:administration & dosage; D002443:Ceftriaxone / Q000008:administration & dosage; D004269:DNA, Bacterial / Q000737:chemistry / Q000235:genetics; D004275:DNA, Ribosomal / Q000737:chemistry / Q000235:genetics; D003937:Diagnosis, Differential; D004697:Endocarditis, Bacterial / Q000188:drug therapy / Q000382:microbiology*; D005839:Gentamicins / Q000008:administration & dosage; D006350:Heart Valve Prosthesis / Q000382:microbiology*; D006801:Humans; D017881:Kingella / Q000145:classification; D007713:Klinefelter Syndrome / Q000150:complications*; D008297:Male; D008969:Molecular Sequence Data; D042805:Neisseria elongata / Q000145:classification / Q000302:isolation & purification*; D016870:Neisseriaceae Infections / Q000188:drug therapy / Q000382:microbiology*; D016459:Prosthesis-Related Infections / Q000188:drug therapy / Q000382:microbiology*; D012336:RNA, Ribosomal, 16S / Q000235:genetics; D017422:Sequence Analysis, DNA
D004269:DNA, Bacterial; D004275:DNA, Ribosomal; D005839:Gentamicins; D012336:RNA, Ribosomal, 16S; D002443:Ceftriaxone; D000658:Amoxicillin