title: Prosthetic valve endocarditis due to Neisseria elongata subsp. elongata in a patient with Klinefelter's syndrome.
abstract: A case is reported of prosthetic valve endocarditis due to Neisseria elongata subsp. elongata in a patient with Klinefelter's syndrome. This is believed to be only the third case of endocarditis reported due to this subspecies. N. elongata is difficult to identify, and is morphologically and biochemically similar to Kingella spp. Sequencing of the 16S rRNA gene is useful for identification. The patient was successfully treated with amoxicillin and gentamicin, followed by ceftriaxone.
authors.affiliation: Department of Clinical Microbiology, Nottingham University Hospitals NHS Trust, Queen's Medical Centre, Nottingham NG7 2UH, UK.
authors.forename: Morgan
authors.initials: M
authors.lastname: Evans
authors.affiliation: Department of Clinical Microbiology, Nottingham University Hospitals NHS Trust, Queen's Medical Centre, Nottingham NG7 2UH, UK.
authors.forename: Farah
authors.initials: F
authors.lastname: Yazdani
authors.affiliation: Laboratory of HealthCare Associated Infection, Centre for Infections, Health Protection Agency, Colindale, London, UK.
authors.forename: Henry
authors.initials: H
authors.lastname: Malnick
authors.affiliation: Laboratory of HealthCare Associated Infection, Centre for Infections, Health Protection Agency, Colindale, London, UK.
authors.forename: Jayesh J
authors.initials: JJ
authors.lastname: Shah
authors.affiliation: Institute of Infections, Immunity and Inflammation, School of Molecular Medical Sciences, Centre for Biomolecular Sciences, University of Nottingham, Nottingham, UK.|Department of Clinical Microbiology, Nottingham University Hospitals NHS Trust, Queen's Medical Centre, Nottingham NG7 2UH, UK.
authors.forename: David P J
authors.initials: DPJ
authors.lastname: Turner
mesh_terms: D000368:Aged; D000658:Amoxicillin / Q000008:administration & dosage; D002443:Ceftriaxone / Q000008:administration & dosage; D004269:DNA, Bacterial / Q000737:chemistry / Q000235:genetics; D004275:DNA, Ribosomal / Q000737:chemistry / Q000235:genetics; D003937:Diagnosis, Differential; D004697:Endocarditis, Bacterial / Q000188:drug therapy / Q000382:microbiology*; D005839:Gentamicins / Q000008:administration & dosage; D006350:Heart Valve Prosthesis / Q000382:microbiology*; D006801:Humans; D017881:Kingella / Q000145:classification; D007713:Klinefelter Syndrome / Q000150:complications*; D008297:Male; D008969:Molecular Sequence Data; D042805:Neisseria elongata / Q000145:classification / Q000302:isolation & purification*; D016870:Neisseriaceae Infections / Q000188:drug therapy / Q000382:microbiology*; D016459:Prosthesis-Related Infections / Q000188:drug therapy / Q000382:microbiology*; D012336:RNA, Ribosomal, 16S / Q000235:genetics; D017422:Sequence Analysis, DNA
chemical_list: D004269:DNA, Bacterial; D004275:DNA, Ribosomal; D005839:Gentamicins; D012336:RNA, Ribosomal, 16S; D002443:Ceftriaxone; D000658:Amoxicillin