title: Treatment-related symptom clusters.
abstract: OBJECTIVE
  To provide a clinical overview of treatment-related symptom clusters.
  
  
  METHODS
  Journal articles, research reports, state of the science papers, and clinical practice experience.
  
  
  CONCLUSIONS
  Although understanding the etiology and interaction of symptoms may lead to targeted interventions, the nurse must often manage symptoms in which the cause or causes cannot be changed or in which there are multiple overlapping etiologies that lead to complex and challenging clinical presentations. Systematic and ongoing evaluation of symptoms, their treatment-related trajectory, and their response to interventions is essential.
  
  
  CONCLUSIONS
  Systematic assessment of symptoms and symptom cluster presence, severity, and distress can guide the practitioner to intervene using evidence-based practice. Individualized care and evaluation of response is needed.
authors.affiliation: AOS Foundation, Phoenix, AZ 85013, USA. Norissa@azoncology.com
authors.forename: Norissa
authors.initials: N
authors.lastname: Honea
authors.forename: Jeannine
authors.initials: J
authors.lastname: Brant
authors.forename: Susan L
authors.initials: SL
authors.lastname: Beck
mesh_terms: D000328:Adult; D000970:Antineoplastic Agents / Q000009:adverse effects / Q000627:therapeutic use; D016000:Cluster Analysis; D005260:Female; D006801:Humans; D009369:Neoplasms / Q000175:diagnosis / Q000188:drug therapy / Q000451:nursing / Q000503:physiopathology* / Q000532:radiotherapy
chemical_list: D000970:Antineoplastic Agents