Killer cell Ig-like receptors CD158a and CD158b display a coactivatory function, involving the c-Jun NH2-terminal protein kinase signaling pathway, when expressed on malignant CD4+ T cells from a patient with Sezary syndrome.
Marie-Cardine
Anne
A
Huet
Delphine
D
Ortonne
Nicolas
N
Remtoula
Natacha
N
Le Gouvello
Sabine
S
Bagot
Martine
M
Bensussan
Armand
A
D017252:CD3 Complex / Q000096:biosynthesis; D015496:CD4-Positive T-Lymphocytes / Q000276:immunology*; D049109:Cell Proliferation; D005786:Gene Expression Regulation; D006801:Humans; D007136:Immunoglobulins / Q000737:chemistry; D048031:JNK Mitogen-Activated Protein Kinases / Q000737:chemistry*; D007694:Killer Cells, Natural / Q000378:metabolism; D007963:Leukocytes, Mononuclear / Q000166:cytology / Q000378:metabolism; D011971:Receptors, Immunologic / Q000096:biosynthesis*; D054340:Receptors, KIR; D054342:Receptors, KIR2DL1; D054344:Receptors, KIR2DL3; D012751:Sezary Syndrome / Q000097:blood* / Q000276:immunology*; D015398:Signal Transduction
D017252:CD3 Complex; D007136:Immunoglobulins; D011971:Receptors, Immunologic; D054340:Receptors, KIR; D054342:Receptors, KIR2DL1; D054344:Receptors, KIR2DL3; D048031:JNK Mitogen-Activated Protein Kinases