The effect of the structure of the nitrogen-containing heterocycle on reversible anticholinesterase effect of heterocyclic thionephosphonates of different hydrophobicity.
Rozengart
E V
EV
Sechenov Institute of Evolutionary Physiology and Biochemistry, Russian Academy of Sciences, pr. Morisa Toreza 44, St. Petersburg 194223, Russia.
Basova
N E
NE
D000110:Acetylcholinesterase / Q000378:metabolism; D000818:Animals; D002091:Butyrylcholinesterase / Q000378:metabolism; D002800:Cholinesterase Inhibitors / Q000737:chemistry* / Q000494:pharmacology*; D004912:Erythrocytes / Q000201:enzymology; D006736:Horses; D006801:Humans; D057927:Hydrophobic and Hydrophilic Interactions; D015394:Molecular Structure; D009584:Nitrogen / Q000737:chemistry*; D063065:Organophosphonates / Q000737:chemistry* / Q000494:pharmacology*; D044967:Serum / Q000201:enzymology; D013329:Structure-Activity Relationship
D002800:Cholinesterase Inhibitors; D063065:Organophosphonates; D000110:Acetylcholinesterase; D002091:Butyrylcholinesterase; D009584:Nitrogen