title: Distribution of phenolic compounds in Middleeuropean taxa of the Achillea millefolium L. aggregate.
abstract: Achillea millefolium L. s.l. is a cytogenetically, morphologically, and chemically polymorphic aggregate. Besides the sesquiterpenes that possess chemotaxonomic relevance and mediate the antiphlogistic activity, the plant contains phenolic compounds such as dicaffeoylquinic acids and flavonoids causing choleretic and spasmolytic effects. To evaluate their contribution to the chemotaxonomy of European taxa of the A. millefolium group, we developed a SPE-HPLC/UV method that allows quantification of the phenolic constituents in the different taxa. The investigated species displayed differences in the quantitative and qualitative composition of phenolic acids and flavonoids. Hence, they seem to be of chemotaxonomic significance, especially for the distinction of the diploid taxa. Combining the obtained results with the data of the sesquiterpene analyses gives a comprehensive insight into the distribution of those pharmacologically relevant plant constituents in the A. millefolium group.
authors.affiliation: Department of Pharmacognosy, University of Vienna, Vienna.
authors.forename: Birgit
authors.initials: B
authors.lastname: Benedek
authors.forename: Noela
authors.initials: N
authors.lastname: Gjoncaj
authors.forename: Johannes
authors.initials: J
authors.lastname: Saukel
authors.forename: Brigitte
authors.initials: B
authors.lastname: Kopp
mesh_terms: D031162:Achillea / Q000737:chemistry* / Q000145:classification*; D002726:Chlorogenic Acid / Q000378:metabolism; D005060:Europe; D005419:Flavonoids / Q000378:metabolism; D010636:Phenols / Q000378:metabolism*; D011801:Quinic Acid / Q000031:analogs & derivatives / Q000378:metabolism; D013045:Species Specificity
chemical_list: D005419:Flavonoids; D010636:Phenols; C472707:caffeoylquinic acid; D011801:Quinic Acid; D002726:Chlorogenic Acid