Chronic hypoxia, physical exercise and PSA: correlation during high-altitude trekking (2004 K2 expedition).
The aim of the present study was to identify the effects of physical exercise on PSA serum levels and the diagnostic validity of PSA in the screening of prostate cancer in subjects undergoing physical exercise during chronic hypoxia. The study was performed during trekking between 3,200 and 5,600 meters of altitude on K2 mountain for 26 days. Mean serum PSA values before and after exposure did not show significant difference due to physical exercise. These data indicate that physical exercise or mountain hypoxia do not affect the diagnostic validity of PSA.
Verratti
Vittore
V
Clinica Urologica, Dipartimento di Scienze dell'Invecchiamento, Università 'G. d'Annunzio', Chieti, Italia. vittorelibero@hotmail.it
Di Giulio
Camillo
C
Di Francesco
Simona
S
Berardinelli
Francesco
F
Pellicciotta
Mario
M
Gidaro
Stefano
S
Zezza
Andrea
A
Tenaglia
Raffaele
R
D000328:Adult; D000368:Aged; D000532:Altitude Sickness / Q000097:blood*; D002908:Chronic Disease; D015444:Exercise; D006801:Humans; D008297:Male; D008875:Middle Aged; D017430:Prostate-Specific Antigen / Q000097:blood*; D011471:Prostatic Neoplasms / Q000097:blood / Q000175:diagnosis*; D015203:Reproducibility of Results
D017430:Prostate-Specific Antigen