Controlled natural cycle IVF: a novel approach for a dominant follicle during an in-vitro maturation cycle.
The objective of this retrospective analysis is to evaluate whether patients developing a dominant follicle in an in-vitro maturation (IVM) programme can be included in a natural cycle IVF (nIVF) programme. In a university teaching hospital, a total of 38 patients with polycystic ovarian syndrome were treated by metformin before undergoing an IVM cycle. Controlled nIVF was performed on seven patients with a dominant follicle. This paper reports three ongoing pregnancies from five embryo transfers in the latter group. Hence, nIVF can be a novel approach for women developing a dominant follicle during an IVM cycle.
Kadoch
Isaac Jacques
IJ
Department of Obstetrics and Gynecology, Antoine Béclère Hospital (AP-HP), 157 rue de la Porte de Trivaux, 92140 Clamart Cedex. ij.kadoch@umontreal.ca
Fanchin
Renato
R
Frydman
Nelly
N
Le Du
Anne
A
Frydman
René
R
D000328:Adult; D005260:Female; D006801:Humans; D007004:Hypoglycemic Agents / Q000494:pharmacology* / Q000627:therapeutic use; D007247:Infertility, Female / Q000188:drug therapy; D008687:Metformin / Q000494:pharmacology* / Q000627:therapeutic use; D006080:Ovarian Follicle / Q000187:drug effects*; D011085:Polycystic Ovary Syndrome / Q000188:drug therapy; D011247:Pregnancy; D027724:Reproductive Techniques, Assisted; D012189:Retrospective Studies
D007004:Hypoglycemic Agents; D008687:Metformin