title: [The evaluation of hemodialysis adequacy during the use of different dialysis membranes].
abstract: BACKGROUND
  Hemodialysis efficacy that significantly influences morbidity and mortality of patients can be evaluated by different widely used indices of adequacy.
  
  
  OBJECTIVE
  The aim of the study was to evaluate the adequacy of hemodialysis in the group of patients on maintenance hemodialysis and to examine the influence of different dialysis membranes on the indices of adequacy and frequency of symptoms and complications developing during dialysis treatment.
  
  
  METHODS
  The study involved 14 patients dialyzed in three successive months with three different types of dialyzers: E3 (Hemomed)--cuprophane membrane, 1.3 m2, F6 (Hemomed)--polysulfone membrane, 1.3 m2, CM23 (Zdravlje)--cuprophane membrane, 1.25 m2. Each type of dialyzers was used during one month, meaning during 12 successive 4-hour hemodialyses.
  
  
  RESULTS
  Mean value of Kt/V index was 1.39 +/- 0.21 for E3 dialyzer, 1.18 +/- 0.24 for F6 dialyzer and 1.44 +/- 0.25 for CM23 dialyzer. The difference between the indices was statistically significant (p < 0.05). Mean protein catabolic rate (PCRn) ranged between 1.6 and 1.7 and no significant difference was found between the dialyzers used. The frequency of hypertension episodes was similar during the hemodialysis with different dialyzers, but the incidence of different symptoms and hypotension episodes was significantly lower during hemodialysis with polysulfone membrane.
  
  
  CONCLUSIONS
  Hemodialysis with three examined types of dialyzers enabled acceptable dialysis adequacy. Dialyzers with cuprophane membrane enabled significantly higher Kt/V index, but the incidence of symptoms and hypotension was significantly lower during hemodialysis with polysulfone membrane.
authors.forename: Zvonimir
authors.initials: Z
authors.lastname: Stasević
authors.forename: Gordana
authors.initials: G
authors.lastname: Subarić-Gorgieva
authors.forename: Jelica
authors.initials: J
authors.lastname: Krcmarević
authors.forename: Radoica
authors.initials: R
authors.lastname: Stolić
authors.forename: Goran
authors.initials: G
authors.lastname: Trajković
mesh_terms: D001672:Biocompatible Materials; D002482:Cellulose / Q000031:analogs & derivatives; D005260:Female; D006801:Humans; D008297:Male; D008567:Membranes, Artificial; D011108:Polymers; D006435:Renal Dialysis / Q000009:adverse effects; D013450:Sulfones; D014508:Urea / Q000378:metabolism
chemical_list: D001672:Biocompatible Materials; D008567:Membranes, Artificial; D011108:Polymers; D013450:Sulfones; C017662:polysulfone P 1700; D014508:Urea; D002482:Cellulose; C009865:cuprammonium cellulose