title: Comparison of the extent of delayed-enhancement cardiac magnetic resonance imaging with and without phase-sensitive reconstruction at 3.0 T.
abstract: OBJECTIVE
  To evaluate phase-sensitive reconstructed images versus magnitude images generated by an inversion recovery pulse sequence for the determination of myocardial infarct size in delayed-enhancement cardiac magnetic resonance (DE-CMR) at 3 T.
  
  
  METHODS
  Thirty patients were examined at 3 T and DE images were obtained 10 minutes after contrast agent administration using a phase-sensitive breath-hold segmented inversion recovery gradient echo sequence. From magnitude and phase images, the percentage of hyperenhanced myocardium was expressed. Contrast-to-noise ratio (CNR) measurements were performed in hyperenhanced and normal myocardium.
  
  
  RESULTS
  We observed excellent correlation and concordance between hyperenhanced myocardium determined on phase-sensitive reconstructed and magnitude images. The mean CNR values were significantly higher in phase-sensitive reconstructed images compared with magnitude images (10.5 +/- 5.4 vs. 6.1 +/- 4.8; P < 0.001).
  
  
  CONCLUSIONS
  DE-CMR with phase-sensitive reconstruction at 3.0 T provides similar results to magnitude images, but with a significantly greater CNR between infarcted and normal myocardium.
authors.affiliation: Unité d'IRM et LE2I (CNRS UMR 5158), CHU Hôpital d'enfants, Dijon, France. alexandre.cochet@neuf.fr
authors.forename: Alexandre
authors.initials: A
authors.lastname: Cochet
authors.forename: Alain
authors.initials: A
authors.lastname: Lalande
authors.forename: Paul M
authors.initials: PM
authors.lastname: Walker
authors.forename: Christophe
authors.initials: C
authors.lastname: Boichot
authors.forename: Renaud
authors.initials: R
authors.lastname: Ciappuccini
authors.forename: Yves
authors.initials: Y
authors.lastname: Cottin
authors.forename: Jean-Eric
authors.initials: JE
authors.lastname: Wolf
authors.forename: François
authors.initials: F
authors.lastname: Brunotte
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002311:Cardiomyopathy, Dilated / Q000473:pathology*; D003287:Contrast Media; D005260:Female; D019786:Gadolinium DTPA; D006801:Humans; D007091:Image Processing, Computer-Assisted; D016014:Linear Models; D019028:Magnetic Resonance Imaging, Cine / Q000379:methods*; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000473:pathology*
chemical_list: D003287:Contrast Media; D019786:Gadolinium DTPA