title: Early embryo cleavage and day 2 mononucleation after intracytoplasmatic sperm injection for predicting embryo implantation potential in single embryo transfer cycles.
abstract: In this study we analyzed the outcome of 275 fresh single embryo transfer cycles of day 2, mononucleate four-cell preembryos that had either cleaved early (n = 175) or not cleaved early (n = 100) 25 to 28 hours after intracytoplasmatic sperm injection. Neither the implantation rate nor the delivery rate showed any difference between the two groups, indicating that when a top-quality preembryo (mononucleate four-cell preembryo on day 2) is transferred, the presence of early cleavage seems to add no additional advantage in predicting the implantation potential of the preembryo.
authors.affiliation: IVF kliniken CURA, Malmö, Sweden. per.sundstrom@curakliniken.se
authors.forename: Per
authors.initials: P
authors.lastname: Sundström
authors.forename: Pia
authors.initials: P
authors.lastname: Saldeen
mesh_terms: D000328:Adult; D001755:Blastocyst / Q000166:cytology*; D002467:Cell Nucleus / Q000502:physiology; D002970:Cleavage Stage, Ovum / Q000502:physiology*; D010064:Embryo Implantation / Q000502:physiology*; D004624:Embryo Transfer; D005260:Female; D006801:Humans; D007247:Infertility, Female / Q000175:diagnosis / Q000628:therapy; D008938:Mitosis / Q000502:physiology; D011247:Pregnancy; D011256:Pregnancy Outcome; D018873:Pregnancy Rate; D020554:Sperm Injections, Intracytoplasmic; D013997:Time Factors