title: Stem cells and their niche: an inseparable relationship.
abstract: A recent Keystone symposium on 'Stem Cell Interactions with their Microenvironmental Niche' was organized by David T. Scadden and Allan C. Spradling. The meeting was held in conjunction with another Keystone symposium, 'Stem Cells and Cancer', at Keystone, Colorado. Among the work that was presented at this meeting, scientists presented data that advances our understanding of the contribution that the niche makes to stem cell maintenance. Novel types of stem cells and niches were also reported and new findings that clarify our understanding of the molecular mechanisms that regulate and maintain stem cells were presented.
authors.affiliation: Stowers Institute for Medical Research, 1000 East 50th Street, Kansas City, MO 64110, USA. tgx@stowers-institute.org
authors.forename: Ting
authors.initials: T
authors.lastname: Xie
authors.forename: Linheng
authors.initials: L
authors.lastname: Li
mesh_terms: D054278:Embryonal Carcinoma Stem Cells; D005109:Extracellular Matrix / Q000378:metabolism; D005854:Germ Cells / Q000502:physiology*; D006412:Hematopoietic Stem Cells / Q000502:physiology*; D014411:Neoplastic Stem Cells / Q000502:physiology*; D009474:Neurons / Q000502:physiology*; D015398:Signal Transduction / Q000502:physiology*