[Round window catheter placement with dexamethasone perfusion for intractable sudden sensorineural hearing loss].
OBJECTIVE
To investigate the efficacy of round window catheter placement with dexamethasone perfusion for 13 patients with intractable sudden sensorineural hearing loss (SSNHL).


METHODS
Dexamethasone (2.5 mg) was perfused transtympanically through round window catheter by Micro-infusion pump. The perfusion was taken twice a day and continued for an hour each time, for a total of 7 days.


RESULTS
Thirteen patients have been followed up for 1 month. Five of them (38.5%) were demonstrated a 17-54 dB improvement in pure-tone threshold average (PTA). The other 8 patients (61.5%) had no effect.


CONCLUSIONS
Round window catheter placement with dexamethasone perfusion is a cost-effective and useful treatment for SSNHL patients who had no effect through conventional therapy, although hearing thresholds of these patients had hardly improved to normal levels.
Sun
Xialing
X
Department of Otolaryngology, the Second Hospital of Xiangya Medical College, Central South University, Changsha, 410011, China.
Ren
Jihao
J
Lu
Yongde
Y
Yin
Tuanfang
T
Wu
Weijing
W
Tang
Yueying
Y
Hu
Binya
B
D000328:Adult; D000368:Aged; D002404:Catheterization; D003907:Dexamethasone / Q000008:administration & dosage* / Q000627:therapeutic use; D005260:Female; D006319:Hearing Loss, Sensorineural / Q000188:drug therapy*; D003639:Hearing Loss, Sudden / Q000188:drug therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012405:Round Window, Ear
D003907:Dexamethasone