[Laparoscopic lymphadenectomy as treatment of endometrial cancer].
OBJECTIVE
This study compares the effects of laparoscopic lymphadenectomy versus those of abdominal lymphadenectomy in patients with endometrial cancer.


METHODS
A prospective randomized study was performed among 80 patients randomly assigned to laparoscopic lymphadenectomy and to abdominal lymphadenectomy in the treatment of endometrial cancer. Clinical outcomes and complications were compared for 1 year of follow-up.


RESULTS
Forty patients were assigned to laparoscopic lymphadenectomy and 40 patients to abdominal lymphadenectomy. The laparoscopic approach was associated with a longer operative time (234.1 min vs 137.3 min) but was less painful (VAS 5.3 vs 7.9; P<0.000) and resulted in a shorter hospital stay (4.4+/-1 vs 7.9+/-1.2 days; P<0.000). At 6 weeks the quality of life was better in patients who had laparoscopic lymphadenectomy (SF-12).


CONCLUSIONS
Laparoscopic lymphadenectomy was associated with a significantly lower rate of major and minor postoperative complications and a better short term quality of life.
Morelli
M
M
Dipartimento di Medicina Sperimentale e Clinica Facoltà di Medicina e Chirurgia, Cattedra di Ginecologia e Ostetricia, Università degli Studi di Catanzaro Magna Graecia, Catanzaro, Italy. morelli.mi@libero.it
Noia
R
R
Costantino
A
A
Chiodo
D
D
Mocciaro
R
R
Caruso
M
M
Cosco
C
C
Lucia
E
E
Curcio
B
B
Gullì
G
G
Amendola
G
G
Zullo
F
F
D000328:Adult; D000368:Aged; D016889:Endometrial Neoplasms / Q000601:surgery*; D005260:Female; D006801:Humans; D010535:Laparoscopy; D008197:Lymph Node Excision / Q000379:methods*; D008875:Middle Aged; D011446:Prospective Studies