title: Novel complex class 1 integron bearing an ISCR1 element in an Escherichia coli isolate carrying the blaCTX-M-14 gene.
abstract: This work identifies an ISCR1-related bla(CTX-M-14) gene, which has never been reported before, from a clinical isolate of Escherichia coli. The bla(CTX-M-14) gene was preceded by an ISCR1 element that was followed by a class 1 integron containing three different insert gene cassettes, i.e., dfrA12, orfF, and aadA2.
authors.affiliation: Research Institute for Antimicrobial Resistance and Department of Laboratory Medicine, Kosin University College of Medicine, 34 Amnam-Dong, Suh-Gu, Busan, Republic of Korea.
authors.forename: Il Kwon
authors.initials: IK
authors.lastname: Bae
authors.forename: You-Nae
authors.initials: YN
authors.lastname: Lee
authors.forename: Wee Gyo
authors.initials: WG
authors.lastname: Lee
authors.forename: Sang Hee
authors.initials: SH
authors.lastname: Lee
authors.forename: Seok Hoon
authors.initials: SH
authors.lastname: Jeong
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D001483:Base Sequence; D004251:DNA Transposable Elements / Q000235:genetics*; D024881:Drug Resistance, Bacterial / Q000235:genetics*; D004926:Escherichia coli / Q000187:drug effects / Q000201:enzymology* / Q000235:genetics / Q000302:isolation & purification; D004927:Escherichia coli Infections / Q000382:microbiology; D029968:Escherichia coli Proteins / Q000235:genetics / Q000378:metabolism; D006801:Humans; D032023:Integrons / Q000235:genetics*; D008297:Male; D008826:Microbial Sensitivity Tests; D008969:Molecular Sequence Data; D018410:Pneumonia, Bacterial / Q000382:microbiology; D017422:Sequence Analysis, DNA; D001618:beta-Lactamases / Q000235:genetics / Q000378:metabolism
chemical_list: D000900:Anti-Bacterial Agents; D004251:DNA Transposable Elements; D029968:Escherichia coli Proteins; C456080:beta-lactamase CTX-M-14; D001618:beta-Lactamases