title: Urological emergency in neonates with congenital hydronephrosis.
abstract: OBJECTIVE
  It is well described that unilateral pelviureteric junction obstruction (PUJO) is a benign condition, because the dilatation resolves spontaneously and the function does not decrease in most of the kidneys. However, there is exceptional PUJO that requires emergent treatment in neonatal periods. The aim of this article is to report the urological emergency and management in neonates with PUJO.
  
  
  METHODS
  Nine children (seven boys and two girls) with PUJO who underwent neonatal emergent treatment during the last 13 years were reviewed. Renal function was evaluated according to decay curve of serum creatinine (SCr) levels corresponding to gestational age (GA) at delivery. Physical examination, ultrasonographic monitoring, and chest and abdominal plain radiographs were repeated in each neonate.
  
  
  RESULTS
  Eight patients were detected prenatally. In five patients, multicystic dysplastic kidney (MCDK) was demonstrated on the contralateral side. Three patients underwent percutaneous puncture of fetal hydronephrosis. Decrease of amniotic fluid was evident in three fetuses. Indications for emergent treatment included mass effect from hydronephrosis in three patients, renal dysfunction in five, and severe urinary tract infection in one. During neonatal periods, a percutaneous nephrostomy tube was placed in seven, and open nephrostomy in one with anorectal malformation. Repeated punctures of the dilated renal pelvis were done in one patient. Renal function after pyeloplasty was stable in eight patients, while it was moderately decreased in one who was associated with oligohydramnios in utero.
  
  
  CONCLUSIONS
  Indications for emergent treatment in neonates with PUJO included mass effect from giant hydronephrosis, renal dysfunction and severe urinary tract infection. At birth, respiratory and circulatory conditions must first be stabilized. In neonates with hydronephrosis of the solitary kidney or severe bilateral PUJO, serial SCr should be monitored to evaluate renal function. Decrease of amniotic fluid suggested renal functional compromise that would not recover after urological management.
authors.affiliation: Department of Urology, Osaka Medical Center and Research Institute for Maternal and Child Health, Osaka, Japan. shimada@mch.pref.osaka.jp
authors.forename: Kenji
authors.initials: K
authors.lastname: Shimada
authors.forename: Fumi
authors.initials: F
authors.lastname: Matsumoto
authors.forename: Mari
authors.initials: M
authors.lastname: Kawagoe
authors.forename: Futoshi
authors.initials: F
authors.lastname: Matsui
mesh_terms: D004630:Emergencies; D004638:Emergency Treatment; D005260:Female; D006801:Humans; D006869:Hydronephrosis / Q000151:congenital* / Q000175:diagnosis / Q000628:therapy; D007231:Infant, Newborn; D008297:Male