[A case of ulcerative colitis relapsed by influenza vaccination].
Although a large number of studies have reported the causes of the exacerbation of ulcerative colitis (UC), the effect of influenza vaccination on the relapse of UC has not been reported. We experienced a case of prompt exacerbation of quiescent UC due to influenza vaccination. A 39-year-old woman was diagnosed as UC 4-years ago and was well controlled with oral mesalazine. She experienced abdominal pain and frequent bowel movements with hematochezia 3 days after the vaccination. On admission, laboratory findings showed elevated erythrocyte sedimentation rate and C-reactive protein. Sigmoidoscopy showed marked edematous mucosa on rectum and sigmoid colon with fine ulceration and spontaneous bleeding. She recovered from the exacerbation of UC after steroid treatment. Vaccination should be administered to the patients with inflammatory bowel disease with the caution of its possible side effects.
Kwon
Oh Sung
OS
Department of Internal Medicine, Eulji University College of Medicine, Eulji Medical Center, Seoul, Korea.
Park
Young Sook
YS
Choi
Jung Ho
JH
Kim
Seong Hwan
SH
Song
Moon Hee
MH
Lee
Han Hyo
HH
Jeon
Dae Won
DW
Kim
Nam In
NI
D000328:Adult; D001799:Blood Sedimentation; D002097:C-Reactive Protein / Q000032:analysis; D003093:Colitis, Ulcerative / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000209:etiology*; D005260:Female; D006801:Humans; D007252:Influenza Vaccines / Q000008:administration & dosage / Q000009:adverse effects*; D012008:Recurrence; D012812:Sigmoidoscopy; D014057:Tomography, X-Ray Computed
D007252:Influenza Vaccines; D002097:C-Reactive Protein