title: Papillary thyroid carcinoma in a patient with sarcoidosis treated with minocycline.
abstract: Long-term treatment with minocycline is occasionally associated with the development of black thyroid syndrome in which thyroid cancer is frequently found. Here, we report a patient with cutaneous, pulmonary and thyroid sarcoidosis who developed papillary thyroid carcinoma in the presence of a black thyroid syndrome after being treated with minocycline for 2.5 years.
authors.affiliation: Department of General Internal Medicine and Endocrinology, Leiden University Medical Centre, Leiden, the Netherlands.
authors.forename: N A
authors.initials: NA
authors.lastname: Bruins
authors.forename: J E
authors.initials: JE
authors.lastname: Oswald
authors.forename: H
authors.initials: H
authors.lastname: Morreau
authors.forename: J
authors.initials: J
authors.lastname: Kievit
authors.forename: S
authors.initials: S
authors.lastname: Pavel
authors.forename: A H M
authors.initials: AH
authors.lastname: Smelt
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000009:adverse effects*; D002291:Carcinoma, Papillary / Q000139:chemically induced* / Q000473:pathology / Q000601:surgery; D005260:Female; D006801:Humans; D008911:Minocycline / Q000009:adverse effects*; D010858:Pigmentation / Q000187:drug effects; D012507:Sarcoidosis / Q000188:drug therapy*; D013964:Thyroid Neoplasms / Q000139:chemically induced* / Q000473:pathology / Q000601:surgery; D013965:Thyroidectomy
chemical_list: D000900:Anti-Bacterial Agents; D008911:Minocycline