title: Injection therapies for soft-tissue lesions.
abstract: Local injection therapies, used in the management of a variety of musculoskeletal pain syndromes, include the local infiltration of substances such as corticosteroid, anaesthetic, sclerosants and botulinum toxin, as well as dry needling alone and neural blockade. In this chapter, a number of injection therapies for soft-tissue-mediated pain are described. The reasoning for their use, potential mechanisms of action and unwanted effects are discussed. The literature relating to their effects is critically reviewed. Practical suggestions for their utilisation in the management of soft-tissue conditions are given and proposals are made for future research in this important area.
authors.affiliation: Addenbrookes Hospital, Hills Road, Cambridge CB2 2QQ, UK. cathy.speed@btinternet.com
authors.forename: Cathy A
authors.initials: CA
authors.lastname: Speed
mesh_terms: D000779:Anesthetics, Local / Q000008:administration & dosage / Q000627:therapeutic use; D001769:Blood; D001905:Botulinum Toxins / Q000008:administration & dosage / Q000627:therapeutic use; D002349:Carpal Tunnel Syndrome / Q000188:drug therapy; D006801:Humans; D015552:Injections, Intralesional; D009140:Musculoskeletal Diseases / Q000188:drug therapy*; D009407:Nerve Block; D010146:Pain / Q000188:drug therapy*; D010525:Peripheral Nerves; D012597:Sclerosing Solutions / Q000008:administration & dosage / Q000627:therapeutic use
chemical_list: D000779:Anesthetics, Local; D012597:Sclerosing Solutions; D001905:Botulinum Toxins