title: Sarcomatous hepatocellular carcinoma without previous anticancer therapy.
abstract: Sarcomatous hepatocellular carcinoma is a rare neoplasm of the liver. A 79-year-old man with a liver tumor was admitted to our hospital. Enhanced computed tomography and magnetic resonance imaging revealed a cystlike lesion, whereas abdominal ultrasonography revealed a solid tumor. The patient underwent medial segmentectomy of the liver for the presumptive diagnosis of atypical hepatocellular carcinoma. Microscopically, the tumor was diagnosed as hepatocellular carcinoma with sarcomatous change. Although anticancer therapy is presumed to be a cause of sarcomatous change in hepatocellular carcinoma, some cases in which patients had not previously undergone anticancer therapy have been reported. Here we report a case of sarcomatous hepatocellular carcinoma without previous anticancer therapy and present a review of the literature.
authors.affiliation: Department of Surgery, Chiba Cancer Center Hospital, 666-2 Nitonachou, Chiba 260-8717, Japan.
authors.forename: Jissei
authors.initials: J
authors.lastname: Yokomizo
authors.forename: Akihiro
authors.initials: A
authors.lastname: Cho
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Yamamoto
authors.forename: Matsuo
authors.initials: M
authors.lastname: Nagata
authors.forename: Nobuhiro
authors.initials: N
authors.lastname: Takiguchi
authors.forename: Osamu
authors.initials: O
authors.lastname: Kainuma
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Soda
authors.forename: Mikito
authors.initials: M
authors.lastname: Mori
authors.forename: Souichi
authors.initials: S
authors.lastname: Narumoto
authors.forename: Takehide
authors.initials: T
authors.lastname: Asano
authors.forename: Munemasa
authors.initials: M
authors.lastname: Ryu
authors.forename: Fukuo
authors.initials: F
authors.lastname: Kondo
mesh_terms: D000368:Aged; D006528:Carcinoma, Hepatocellular / Q000175:diagnosis* / Q000601:surgery; D003937:Diagnosis, Differential; D006498:Hepatectomy / Q000379:methods; D006801:Humans; D008113:Liver Neoplasms / Q000175:diagnosis* / Q000601:surgery; D008279:Magnetic Resonance Imaging; D008297:Male; D012509:Sarcoma / Q000175:diagnosis* / Q000601:surgery; D014057:Tomography, X-Ray Computed