title: Analytical interferences of drugs in the chemical examination of urinary protein.
abstract: OBJECTIVE
  To evaluate the potential analytical interference of 24 drugs in the urinary protein.
  
  
  METHODS
  The analysis was done using Multistix 10SG and comparing the results of controls with urine samples supplemented with drugs.
  
  
  RESULTS
  Positive interferences occurred with ciprofloxacin, quinine and chloroquine in supratherapeutical concentrations, while chloroquine interfered also in therapeutical concentration.
  
  
  CONCLUSIONS
  False proteinuria in test-strips can lead to erroneous interpretations with repercussion in clinical procedures and higher costs to the health system.
authors.affiliation: Laboratório de Análises Clínicas, Hospital Universitário, Universidade Federal de Santa Catarina, Campus Universitário Trindade, 88.040-970 Florianópolis, Santa Catarina, Brazil.
authors.forename: Adriana
authors.initials: A
authors.lastname: Scotti da Silva-Colombeli
authors.forename: Miriam
authors.initials: M
authors.lastname: Falkenberg
mesh_terms: D002738:Chloroquine / Q000032:analysis; D002939:Ciprofloxacin / Q000032:analysis; D019411:Clinical Laboratory Techniques / Q000295:instrumentation / Q000379:methods; D006801:Humans; D004364:Pharmaceutical Preparations / Q000032:analysis*; D011507:Proteinuria / Q000175:diagnosis* / Q000652:urine*; D011803:Quinine / Q000032:analysis; D011934:Reagent Strips; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity
chemical_list: D004364:Pharmaceutical Preparations; D011934:Reagent Strips; D002939:Ciprofloxacin; D002738:Chloroquine; D011803:Quinine