title: Two giant renal aneurysms and renal arteriovenous fistula associated with cardiac insufficiency and a sustained elevation of atrial natriuretic peptide and brain natriuretic peptide.
abstract: A 64-year-old man presented with chief complaints of exertional dyspnea and palpitation. He had previously undergone left nephrolithotomies twice. A chest roentgenogram showed pleural effusion on both sides with cardiac dilation, and electrocardiography showed a frequent occurrence of ventricular premature contractions. An echocardiogram showed diffuse hypokinesis of the left ventricular wall motion (ejection fraction, 45%) and dilation of the left ventricle (left ventricular end-diastolic dimension, 61 mm). We administered diuretics, ACE inhibitors and a beta-adrenergic blocking agent after making a diagnosis of cardiac insufficiency. Because coronary angiography showed 90% stenosis of the left anterior descending coronary artery (No. 7), we performed coronary angioplasty in this locus. Though both the left ventricular wall motion and ejection fraction improved, and the clinical symptoms disappeared, the left ventricular end-diastolic dimension, and arrhythmia did not improve. Furthermore, the brain natriuretic peptide increased despite these treatments. Thereafter, a left renal artery aneurysm (extrarenal aneurysm measuring 5 cm in diameter and an intrarenal aneurysm measuring 3 cm in diameter) and a left renal arteriovenous fistula were discovered when abdominal echography was performed because of epigastric discomfort. As a result, a left total nephrectomy was performed. Subsequently, the left ventricular end-diastolic dimension and arrhythmia improved, and the brain natriuretic peptide returned to a normal value. We herein report a case that developed cardiac insufficiency due to a renal aneurysm and renal arteriovenous fistula after undergoing left nephrolithotomies twice.
authors.affiliation: Department of Internal Medicine, Division of Coronary Heart Disease, Hyogo College of Medicine, Nishinomiya-City, Hyogo, Japan. sakoda@msd.biglobe.ne.jp
authors.forename: Tsuyoshi
authors.initials: T
authors.lastname: Sakoda
authors.forename: Arisa
authors.initials: A
authors.lastname: Nishimukai
authors.forename: Takeshi
authors.initials: T
authors.lastname: Tsujino
authors.forename: Tohru
authors.initials: T
authors.lastname: Masuyama
authors.forename: Yuji
authors.initials: Y
authors.lastname: Miyamoto
authors.forename: Mitsumasa
authors.initials: M
authors.lastname: Oyanagi
mesh_terms: D000368:Aged; D000783:Aneurysm / Q000175:diagnosis / Q000473:pathology*; D001164:Arteriovenous Fistula / Q000175:diagnosis / Q000473:pathology*; D009320:Atrial Natriuretic Factor / Q000097:blood*; D002303:Cardiac Output, Low; D006801:Humans; D007668:Kidney / Q000098:blood supply / Q000473:pathology; D007674:Kidney Diseases / Q000175:diagnosis / Q000378:metabolism / Q000473:pathology; D008297:Male; D020097:Natriuretic Peptide, Brain / Q000097:blood*; D012077:Renal Artery / Q000473:pathology*
chemical_list: D020097:Natriuretic Peptide, Brain; D009320:Atrial Natriuretic Factor