title: An annotation infrastructure for the analysis and interpretation of Affymetrix exon array data.
abstract: Affymetrix exon arrays contain probesets intended to target every known and predicted exon in the entire genome, posing significant challenges for high-throughput genome-wide data analysis. X:MAP http://xmap.picr.man.ac.uk, an annotation database, and exonmap http://www.bioconductor.org/packages/2.0/bioc/html/exonmap.html, a BioConductor/R package, are designed to support fine-grained analysis of exon array data. The system supports the application of standard statistical techniques, prior to the use of genome scale annotation to provide gene-, transcript- and exon-level summaries and visualization tools.
authors.affiliation: Bioinformatics Group, Cancer Research UK, Paterson Institute for Cancer Research, The University of Manchester, Christie Hospital Site, Wilmslow Road, Manchester M20 4BX, UK. mokoniewski@picr.man.ac.uk
authors.forename: Michał J
authors.initials: MJ
authors.lastname: Okoniewski
authors.forename: Tim
authors.initials: T
authors.lastname: Yates
authors.forename: Siân
authors.initials: S
authors.lastname: Dibben
authors.forename: Crispin J
authors.initials: CJ
authors.lastname: Miller
mesh_terms: D003196:Computer Graphics; D015342:DNA Probes; D030561:Databases, Nucleic Acid; D005091:Exons; D015894:Genome, Human / Q000235:genetics*; D006801:Humans; D015233:Models, Statistical; D012984:Software
chemical_list: D015342:DNA Probes