title: Effect of pulsed magnetic field therapy on pain reported by human volunteers in a laboratory model of acute pain.
abstract: BACKGROUND
  Pulsed magnetic field therapy (PMFT) is a non-invasive, simple technique used extensively for the treatment of muscle pain. However, evidence to support its use from well-designed, clinical, or experimental studies is sparse.
  
  
  METHODS
  We have utilized an acute pain model to perform a randomized, double-blinded, placebo-controlled, crossover-study on 10 male (18-40 yr) volunteers. Pain was elicited by infusion of hypertonic saline 5% into the brachioradialis muscle of the non-dominant arm on two occasions, at least 1 week apart. Subjects received active or sham PMFT for 30 min in a randomized order delivered by two identical, commercially available machines (PulsePack 6000, Quantum Techniks). The active machine delivered a M-wave magnetic pulse (1.25 Hz, 3 ms width, 600 Gauss); the sham device was deactivated and delivered no magnetic energy. Pain was assessed at 15-s intervals, and area under the visual analogue score (VAS) pain curve (AUCp) was calculated using the trapezoid method.
  
  
  RESULTS
  There were no significant differences in mean VAS pain scores between the two machines at any time. In addition, there were no significant differences with respect to mean (sem) maximum pain score [sham 60 (8), active 63 (9) mm; P = 0.66, 95% CI -18 to 12 mm] or AUCp [sham 463 (50), active 499 (90); P = 0.64, 95% CI -201 to 129].
  
  
  CONCLUSIONS
  We conclude that, using the electromagnetic characteristics of the machine in this study, the PMFT had no effect on pain in our experimental model. More work is required to provide an evidence base in support of the use of this technique for pain.
authors.affiliation: University Hospitals Coventry and Warwickshire NHS Trust, Clifford Bridge Road, Coventry CV2 2DX, UK.
authors.forename: M I
authors.initials: MI
authors.lastname: Fernandez
authors.forename: P J
authors.initials: PJ
authors.lastname: Watson
authors.forename: D J
authors.initials: DJ
authors.lastname: Rowbotham
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D018592:Cross-Over Studies; D004311:Double-Blind Method; D004574:Electromagnetic Fields; D006801:Humans; D008280:Magnetics / Q000627:therapeutic use*; D008297:Male; D010146:Pain / Q000209:etiology; D059408:Pain Management; D010147:Pain Measurement / Q000379:methods; D012462:Saline Solution, Hypertonic
chemical_list: D012462:Saline Solution, Hypertonic