Three new sesquiterpenoids from the aerial parts of Homalomena occulta.
Three new eudesmane-type sesquiterpenoids, compounds 1-3, and eight known constituents, including mucrolidin (4), 1beta,4beta,7alpha-trihydroxyeudesmane (5), 1beta,4beta,6beta,11-tetrahydroxyeudesmane (6), oplodiol (7), bullatantriol (8), acetylbullatantriol (9), homalomenol (10), and maristeminol (11), were isolated from the aerial parts of Homalomena occulta. Their structures were determined by interpretation of spectroscopic and mass-spectrometric data, and their antimicrobial activities toward six different bacterial strains were tested. Most of the compounds showed weak antibacterial activities in an agar-diffusion assay.
Wang
Yi-Fen
YF
State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, PR China.
Wang
Xian-You
XY
Lai
Guo-Fang
GF
Lu
Chun-Hua
CH
Luo
Shi-De
SD
D000900:Anti-Bacterial Agents / Q000302:isolation & purification / Q000494:pharmacology*; D029064:Araceae / Q000737:chemistry*; D001562:Benzimidazoles / Q000302:isolation & purification / Q000494:pharmacology; D002681:China; D003517:Cyclopentanes / Q000302:isolation & purification / Q000494:pharmacology; D009284:Naphthols / Q000302:isolation & purification / Q000494:pharmacology; D012717:Sesquiterpenes / Q000302:isolation & purification / Q000494:pharmacology*
C436284:2-cyclopentyl-5-(5-isoquinolylsulfonyl)-6-nitro-1H-benzo(D)imidazole; D000900:Anti-Bacterial Agents; D001562:Benzimidazoles; D003517:Cyclopentanes; D009284:Naphthols; D012717:Sesquiterpenes; C487643:oplodiol