title: Late corneal hydrops after penetrating keratoplasty for keratoconus.
abstract: OBJECTIVE
  To report 2 cases of corneal hydrops occurring in eyes with previously healthy corneal grafts.
  
  
  METHODS
  Retrospective case series. A report of 2 presenting cases. Both patients underwent a full ophthalmic clinical examination and anterior segment optical coherence tomography (OCT).
  
  
  RESULTS
  Two patients with longstanding corneal grafts for keratoconus presented with an acute painful red eye and reduced vision. They were found to have acute hydrops with breaks in and detachments of Descemet membrane.
  
  
  CONCLUSIONS
  Keratoconic patients with longstanding corneal grafts who present acutely with corneal edema must be carefully examined not only for signs of graft rejection or failure but also for acute hydrops. Important differentiating signs may be a Descemet break or detachment and the presence of stromal edema across the donor-host corneal interface.
authors.affiliation: Cornea and External Disease Service, Moorfields Eye Hospital, London, United Kingdom. Daniel_Ezra@hotmail.com
authors.forename: Daniel G
authors.initials: DG
authors.lastname: Ezra
authors.forename: Jodhbir S
authors.initials: JS
authors.lastname: Mehta
authors.forename: Bruce D
authors.initials: BD
authors.lastname: Allan
mesh_terms: D000328:Adult; D015715:Corneal Edema / Q000188:drug therapy / Q000209:etiology*; D003886:Descemet Membrane / Q000473:pathology; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D007640:Keratoconus / Q000601:surgery*; D015948:Keratoplasty, Penetrating; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D012189:Retrospective Studies; D012422:Rupture, Spontaneous; D041623:Tomography, Optical Coherence
chemical_list: D005938:Glucocorticoids