Heartening news for head muscle development.
Branchiomeric craniofacial muscles differ from all other skeletal muscles with respect to embryological origin, motor innervation and upstream activators of myogenesis. A series of recent studies has revealed a striking juxtaposition and overlapping genetic program of craniofacial skeletal muscle progenitor cells with a population of cells giving rise to cardiac muscle. The divergent myogenic fates of adjacent progenitor cells revealed by these data provide a new framework for the study of craniofacial myogenesis.
Grifone
Raphaëlle
R
Developmental Biology Institute of Marseilles - Luminy, Inserm Avenir Group, UMR 6216 CNRS-Université de la Méditerranée, Campus de Luminy Case 907, 13288 Marseilles Cedex 9, France.
Kelly
Robert G
RG
D000818:Animals; D001934:Branchial Region / Q000196:embryology* / Q000378:metabolism; D018507:Gene Expression Regulation, Developmental; D006257:Head / Q000196:embryology* / Q000502:physiology; D006321:Heart / Q000196:embryology; D006801:Humans; D008954:Models, Biological; D024510:Muscle Development / Q000235:genetics; D018482:Muscle, Skeletal / Q000196:embryology*; D009206:Myocardium / Q000378:metabolism; D015398:Signal Transduction