title: A case of hippocampal laminar necrosis following complex partial status epilepticus.
abstract: Cortical laminar necrosis (CLN) is a metabolic injury pattern usually observed after cerebral hypoxia, hypoglycemia, or ischemia. We report serial magnetic resonance imaging findings in a patient with complex partial status epilepticus (SE) developing a band-like, T1-hyperintense lesion consistent with CLN along the surface of the left hippocampus without concurrent other causes of CLN. This observation suggests a direct pathogenetic link between SE and CLN involving combined damage to neurons and glia.
authors.affiliation: Department of Neurology, University of Greifswald, Greifswald, Germany. alexander.heinrich@bkh-guenzburg.de
authors.forename: A
authors.initials: A
authors.lastname: Heinrich
authors.forename: U
authors.initials: U
authors.lastname: Runge
authors.forename: M
authors.initials: M
authors.lastname: Kirsch
authors.forename: A V
authors.initials: AV
authors.lastname: Khaw
mesh_terms: D000369:Aged, 80 and over; D001925:Brain Damage, Chronic / Q000209:etiology / Q000473:pathology* / Q000503:physiopathology; D004827:Epilepsy / Q000150:complications / Q000473:pathology* / Q000503:physiopathology; D005911:Gliosis / Q000209:etiology / Q000473:pathology / Q000503:physiopathology; D006624:Hippocampus / Q000473:pathology* / Q000503:physiopathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009336:Necrosis / Q000209:etiology / Q000473:pathology / Q000503:physiopathology; D009410:Nerve Degeneration / Q000209:etiology / Q000473:pathology / Q000503:physiopathology; D013226:Status Epilepticus / Q000150:complications / Q000473:pathology* / Q000503:physiopathology