title: Ethambutol toxicity manifesting as acute onset psychosis.
abstract: Ethambutol is commonly used for the treatment of tuberculous and atypical mycobacterial infection. Central nervous system (CNS) toxicity other than optic neuropathy is not widely reported. A 40-year-old man with advanced HIV infection and Mycobacterium avium complex infection experienced rapid cognitive decline after commencement of ethambutol, and symptoms fully resolved with cessation.
authors.affiliation: Canberra Sexual Health Centre, The Canberra Hospital, Canberra, ACT, Australia. sarah.martin@act.gov.au
authors.forename: S J
authors.initials: SJ
authors.lastname: Martin
authors.forename: F J
authors.initials: FJ
authors.lastname: Bowden
mesh_terms: D000328:Adult; D000995:Antitubercular Agents / Q000009:adverse effects*; D004359:Drug Therapy, Combination; D004977:Ethambutol / Q000009:adverse effects*; D006801:Humans; D008297:Male; D015270:Mycobacterium avium-intracellulare Infection / Q000188:drug therapy*; D011605:Psychoses, Substance-Induced / Q000209:etiology*
chemical_list: D000995:Antitubercular Agents; D004977:Ethambutol