title: A review of depleted uranium biological effects: in vitro and in vivo studies.
abstract: The use of depleted uranium in armor-penetrating munitions remains a source of controversy because of the numerous unanswered questions about its long-term health effects. Although no conclusive epidemiologic data have correlated DU exposure to specific health effects, studies using cultured cells and laboratory rodents continue to suggest the possibility of leukemogenic, genetic, reproductive, and neurological effects from chronic exposure. Until issues of concern are resolved with further research, the use of depleted uranium by the military will continue to be controversial.
authors.affiliation: Uniformed Services University of the Health Sciences, Armed Forces Radiobiology Research Institute, 8901 Wisconsin Avenue, Building 42, Bethesda, MD 20889-5603, USA. millera@afrri.usuhs.mil
authors.forename: Alexandra C
authors.initials: AC
authors.lastname: Miller
authors.forename: David
authors.initials: D
authors.lastname: McClain
mesh_terms: D000818:Animals; D004781:Environmental Exposure; D006801:Humans; D008889:Military Personnel; D009381:Neoplasms, Radiation-Induced; D011848:Radioactive Pollutants / Q000493:pharmacokinetics; D051381:Rats; D017207:Rats, Sprague-Dawley; D014501:Uranium / Q000009:adverse effects* / Q000493:pharmacokinetics; D014857:Warfare
chemical_list: D011848:Radioactive Pollutants; D014501:Uranium