title: Influence of z overscanning on normalized effective doses calculated for pediatric patients undergoing multidetector CT examinations.
abstract: The purpose of this study was to evaluate the effect of z overscanning on normalized effective dose for pediatric patients undergoing multidetector-computed tomography (CT) examinations. Five commercially available mathematical anthropomorphic phantoms representing newborn, 1-, 5-, 10-, and 15-year-old patients and the Monte Carlo N-Particle (MCNP, version 4C2) radiation transport code were employed in the current study to simulate pediatric CT exposures. For all phantoms, axial and helical examinations at 120 kV tube voltage were simulated. Scans performed at 80 kV were also simulated. Sex-specific normalized effective doses were estimated for four standard CT examinations i.e., head-neck, chest, abdomen-pelvis, and trunk, for all pediatric phantoms. Data for both axial and helical mode acquisition were obtained. In the helical mode, z overscanning was taken into account. The validity of the Monte Carlo results was verified by comparison with dose data obtained using thermoluminescence dosimetry and a physical pediatric anthropomorphic phantom simulating a 10-year-old child. In all cases normalized effective dose values were found to increase with increasing z overscanning. The percentage differences in normalized data between axial and helical scans may reach 43%, 70%, 36%, and 26% for head-neck, chest, abdomen-pelvis, and trunk studies, respectively. Normalized data for female pediatric patients was in general higher compared to male patients for all ages, examined regions, and z overscanning values. For both male and female children, the normalized effective dose values were reduced as the age was increased. For the same typical exposure conditions, dose values decreased when lower tube voltage was used; for a 1-year-old child, for example, the effective dose was 3.8 times lower when 80 kV instead of 120 kV was used. Normalized data for the estimation of effective dose to pediatric patients undergoing standard axial and helical CT examinations on an multidetector CT system were calculated. This data was found to depend strongly on CT acquisition mode and exposure parameters as well as patient age and sex. The effective dose from a pediatric CT scan performed in axial mode was always considerably lower compared to the corresponding scan performed in helical mode, due to the additional tissue regions exposed to the primary beam in helical examinations as a result of z overscanning.
authors.affiliation: Department of Medical Physics, Faculty of Medicine, University of Crete, P.O. Box 2208, Iraklion 71003, Crete, Greece.
authors.forename: Antonis
authors.initials: A
authors.lastname: Tzedakis
authors.forename: John
authors.initials: J
authors.lastname: Damilakis
authors.forename: Kostas
authors.initials: K
authors.lastname: Perisinakis
authors.forename: Apostolos
authors.initials: A
authors.lastname: Karantanas
authors.forename: Spiros
authors.initials: S
authors.lastname: Karabekios
authors.forename: Nicholas
authors.initials: N
authors.lastname: Gourtsoyiannis
mesh_terms: D000293:Adolescent; D001822:Body Burden; D002648:Child; D002675:Child, Preschool; D003198:Computer Simulation; D004735:Energy Transfer; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008954:Models, Biological; D009010:Monte Carlo Method; D011829:Radiation Dosage; D011874:Radiometry / Q000379:methods*; D012062:Relative Biological Effectiveness; D018570:Risk Assessment / Q000379:methods*; D012307:Risk Factors; D014057:Tomography, X-Ray Computed; D051598:Whole Body Imaging