title: Herpes simplex keratitis after intravitreal triamcinolone acetonide.
abstract: OBJECTIVE
  To report a case of recurrent herpes simplex virus (HSV) epithelial keratitis after intravitreal triamcinolone acetonide injection for the treatment of diabetic macular edema.
  
  
  METHODS
  Case report.
  
  
  RESULTS
  We describe a case of a 59-year-old woman with a history of ocular HSV disease and severe proliferative diabetic retinopathy. She received an intravitreal injection of triamcinolone acetonide for macular edema in the right eye. One week later, she developed foreign body sensation, redness, and photophobia in the same eye. Slit-lamp examination revealed a corneal epithelial dendritic lesion. She was diagnosed with a recurrence of HSV epithelial keratitis and was treated with oral acyclovir 400 mg, 5 times a day, with good resolution of HSV signs and symptoms.
  
  
  CONCLUSIONS
  Intravitreal triamcinolone acetonide injection may result in reactivation of HSV keratitis.
authors.affiliation: Department of Ophthalmology and Visual Sciences, University of Michigan, W.K. Kellogg Eye Center, Ann Arbor, MI, USA.
authors.forename: Roni M
authors.initials: RM
authors.lastname: Shtein
authors.forename: Roslyn M
authors.initials: RM
authors.lastname: Stahl
authors.forename: Stephen J
authors.initials: SJ
authors.lastname: Saxe
authors.forename: Shahzad I
authors.initials: SI
authors.lastname: Mian
mesh_terms: D000212:Acyclovir / Q000627:therapeutic use; D000998:Antiviral Agents / Q000627:therapeutic use; D003930:Diabetic Retinopathy / Q000188:drug therapy; D005260:Female; D005938:Glucocorticoids / Q000009:adverse effects*; D018259:Herpesvirus 1, Human / Q000502:physiology; D006801:Humans; D007267:Injections; D016849:Keratitis, Herpetic / Q000188:drug therapy / Q000209:etiology*; D008269:Macular Edema / Q000188:drug therapy; D008875:Middle Aged; D012008:Recurrence; D014222:Triamcinolone Acetonide / Q000009:adverse effects*; D014775:Virus Activation / Q000187:drug effects*; D014822:Vitreous Body
chemical_list: D000998:Antiviral Agents; D005938:Glucocorticoids; D014222:Triamcinolone Acetonide; D000212:Acyclovir