title: Whole-liver graft without the retrohepatic inferior vena cava for sequential (domino) living donor liver transplantation.
abstract: Grafts used in Domino liver transplantation (LT) obtained from living donor liver transplantation (LDLT) for familial amyloid polyneuropathy (FAP) patients have been mainly used as reduced grafts. Because of small-for-size problems seen in LDLT, using whole liver grafts could improve post-LT outcome. Eight consecutive Domino LDLT using whole livers without retrohepatic inferior vena cava (IVC) from FAP patients were retrospectively analyzed. The graft weight/recipient's body weight ratio (GWRW) in the domino recipients ranged from 1.28% to 2.4% (mean: 1.52). Multiple vascular reconstructions in the whole-liver domino LT resulted in longer than usual warm ischemia time (mean: 64 min); however immediate post-operative recovery of hepatic function was uneventful. At 8-40 months after the transplant, all the FAP patients are well and all of the domino recipients are alive. Domino LT using a whole FAP liver from a LDLT for a FAP patient presents satisfactory results, even though the transplant procedure is technically complicated.
authors.affiliation: Department of Pediatric Surgery and Transplantation, Faculty of Medical and Pharmaceutical Sciences, Kumamoto University, Kumamoto, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Inomata
authors.forename: M E
authors.initials: ME
authors.lastname: Zeledón
authors.forename: K
authors.initials: K
authors.lastname: Asonuma
authors.forename: H
authors.initials: H
authors.lastname: Okajima
authors.forename: T
authors.initials: T
authors.lastname: Takeichi
authors.forename: T
authors.initials: T
authors.lastname: Ishiko
authors.forename: Y
authors.initials: Y
authors.lastname: Ando
mesh_terms: D000293:Adolescent; D000328:Adult; D028227:Amyloid Neuropathies, Familial / Q000601:surgery*; D006801:Humans; D016031:Liver Transplantation / Q000379:methods*; D019520:Living Donors / Q000706:statistics & numerical data; D008875:Middle Aged; D012189:Retrospective Studies; D016896:Treatment Outcome; D014682:Vena Cava, Inferior / Q000601:surgery*