title: A study evaluating the safety and efficacy of the VelaSmooth system in the treatment of cellulite.
abstract: BACKGROUND
  Most cellulite treatments are limited in their effectiveness. A combination of radiofrequency energy, infrared light and mechanical manipulation of the skin and fat merits further examination.
  
  
  OBJECTIVE
  Subjects were treated with a device combining these energies to evaluate its safety and efficacy.
  
  
  METHODS
  Sixteen subjects with cellulite were treated twice weekly for 6 weeks with the VelaSmooth system. One thigh was treated while the other served as a control. Treatment efficacy was measured through circumferential measurements of both thighs and by having the investigator and an independent evaluator grade visual improvement during follow-up visits. Five patients provided blood specimens for assessment of lipid and hormone levels and liver function. Two subjects provided three biopsies each in order to monitor the level of estrogen and progesterone receptors.
  
  
  RESULTS
  The overall thigh circumference decreased in 71.87% of the treated legs. The mean decrease was 0.44 cm of the lower thigh and 0.53 cm of the upper thigh. There was significant visual improvement in cellulite and skin texture. At the final follow-up visit, 50% of subjects had greater than 25% improvement (good be very good).
  
  
  CONCLUSIONS
  This study showed positive results. Future studies employing higher energy levels and additional treatments will likely augment the results of the present study.
authors.affiliation: Weill Medical College of Cornell University, New York, NY, USA. nssderm@sadickdermatology.com
authors.forename: Neil
authors.initials: N
authors.lastname: Sadick
authors.forename: Cynthia
authors.initials: C
authors.lastname: Magro
mesh_terms: D000328:Adult; D002081:Buttocks; D003357:Cosmetic Techniques; D005260:Female; D006801:Humans; D007259:Infrared Rays / Q000627:therapeutic use; D028022:Low-Level Light Therapy / Q000379:methods*; D008405:Massage; D008875:Middle Aged; D000078702:Radiofrequency Therapy; D050151:Subcutaneous Fat / Q000528:radiation effects; D013396:Suction