title: [Hypocalcemic cardiomyopathy secondary to hypoparathyroidism after a thyroidectomy: report of one case].
abstract: Calcium plays a central role in ventricular function. We report a 37 year-old woman with chronic hypoparathyroidism and hypocalcemia secondary to a thyroidectomy performed when she was 18 years old, as treatment for a Graves Basedow's disease. She did not have previous cardiac symptoms and rapid progressive congestive heart failure developed after the beginning of levothyroxin supplementation for post operative hypothyroidism. Echocardiography revealed severe systolic and diastolic left ventricular dysfunction, mitral and tricuspid valve insufficiency, systolic pulmonary hypertension, left atrial enlargement and pericardial effusion. Calcium supplementation in addition to diuretics, captopril and digoxin were followed by rapid clinical improvement. Follow up until 18 months showed persistent left ventricular dilatation and systolic dysfunction, with improvement of all the other echocardiographic findings.
authors.affiliation: Servicio de Medicina, Hospital Regional de Talca, Talca, Chile. joslam@mixmail.com
authors.forename: José
authors.initials: J
authors.lastname: Lam
authors.forename: Patricio
authors.initials: P
authors.lastname: Maragaño
authors.forename: Bárbara
authors.initials: B
authors.lastname: Lépez
authors.forename: Loreto
authors.initials: L
authors.lastname: Vásquez
mesh_terms: D000328:Adult; D002118:Calcium / Q000627:therapeutic use; D002908:Chronic Disease; D003937:Diagnosis, Differential; D005260:Female; D006333:Heart Failure / Q000209:etiology* / Q000473:pathology; D006801:Humans; D006996:Hypocalcemia / Q000150:complications* / Q000188:drug therapy; D007011:Hypoparathyroidism / Q000150:complications*; D013965:Thyroidectomy / Q000009:adverse effects*; D013974:Thyroxine / Q000009:adverse effects / Q000627:therapeutic use; D016277:Ventricular Function, Left / Q000187:drug effects
chemical_list: D013974:Thyroxine; D002118:Calcium