Familial multiple angiolipomatosis.
An 80-year-old man presented with a 50-year history of asymptomatic, subcutaneous masses on the arms, trunk, and legs. His father and maternal grandmother had had similar lesions. Histopathologic examination showed a benign angiolipoma; the same diagnosis has been made on several previous biopsy specimens. This patient's history and physical examination support the diagnosis of familial angiolipomatosis, which is a benign, autosomal-dominant condition that may be regarded as a subtype of familial multiple lipomatosis (FML) or as a distinct entity. Management of this condition may include liposuction or surgery to reduce the tumor burden.
Abbasi
Naheed R
NR
New York University Department of Dermatology, USA.
Brownell
Isaac
I
Fangman
William
W
D000369:Aged, 80 and over; D000798:Angiomatosis / Q000235:genetics* / Q000473:pathology; D003937:Diagnosis, Differential; D006801:Humans; D008069:Lipomatosis, Multiple Symmetrical / Q000235:genetics* / Q000473:pathology; D008297:Male; D012720:Severity of Illness Index; D012867:Skin / Q000473:pathology