title: No ecological effect modification of the association between negative life experiences and later psychopathology in adolescence: A longitudinal community study in adolescents.
abstract: BACKGROUND
  The aim of the study was to examine the potential contribution of exposure to bullying and adverse life events to the development of psychopathology in adolescents, and possible effect modification by neighbourhood social capital.
  
  
  METHODS
  Two waves of routine, longitudinal, standard health examinations at local community paediatric health services, pertaining to 749 adolescents living in Maastricht (The Netherlands) who were attending second grade of secondary school (age 13/14 years) and approximately 2 years later going to the fourth grade (age 15/16 years), were analysed. A self-report questionnaire was used, including measures of psychopathology and two measures of negative life experiences, exposure to bullying and adverse life events, that were available for both age groups and subjected to (multilevel) regression analysis.
  
  
  RESULTS
  Exposure to bullying in the past school-year as well as the experience of adverse life events over a 12 month period, at the age of 13/14 years, predicted an increase in psychopathology at follow-up. Exposure to bullying was associated with the development of hyperactivity and emotional problems, while the experience of adverse life events predicted the development of conduct problems. Family-related adverse events had greatest effect sizes. Effects of bullying and adverse life events were not moderated by neighbourhood social capital.
  
  
  CONCLUSIONS
  Negative life experiences impact on liability to psychopathology in adolescents independent of the wider social environment.
authors.affiliation: Department of Psychiatry and Neuropsychology, South Limburg Mental Health Research and Teaching Network, EURON, Maastricht University, 6200 MD Maastricht, The Netherlands. n.gunther@sp.unimaas.nl
authors.forename: Nicole
authors.initials: N
authors.lastname: Gunther
authors.forename: Marjan
authors.initials: M
authors.lastname: Drukker
authors.forename: Frans
authors.initials: F
authors.lastname: Feron
authors.forename: Jim
authors.initials: J
authors.lastname: van Os
mesh_terms: D000293:Adolescent; D000342:Affective Symptoms / Q000175:diagnosis / Q000523:psychology; D000374:Aggression / Q000523:psychology*; D001289:Attention Deficit Disorder with Hyperactivity / Q000175:diagnosis / Q000523:psychology; D019955:Conduct Disorder / Q000175:diagnosis / Q000523:psychology; D004291:Dominance-Subordination; D005195:Family Relations; D005260:Female; D006801:Humans; D008016:Life Change Events; D008137:Longitudinal Studies; D008297:Male; D008403:Mass Screening; D001523:Mental Disorders / Q000175:diagnosis / Q000523:psychology*; D009426:Netherlands; D011599:Psychopathology; D012307:Risk Factors; D012931:Social Environment; D012959:Socioeconomic Factors; D011795:Surveys and Questionnaires