title: [Liver pathology in idiopathic portal hypertension].
abstract: OBJECTIVE
  To study the histopathological changes of livers in idiopathic portal hypertension (IPH).
  
  
  METHODS
  Liver specimens from 29 cases with idiopathic portal hypertension were studied. Histological preparations of the livers were stained with haematoxylin eosin and Masson's trichrome; reticular fibers in the liver tissues were demonstrated. The slides were also stained using some immunohistochemistry methods, and the pathological changes of the livers were analyzed.
  
  
  RESULTS
  The characteristic changes found in these IPH livers were dense portal fibrosis; obliteration, with or without phlebitis, of the branches of the portal vein; dilatation of the sinusoids; atrophy and nodular hyperplasia of liver cells.
  
  
  CONCLUSIONS
  Histopathological changes of the livers in IPH are dense portal fibrosis, portal vein branch obliteration and nodular hyperplasia of liver cells. These are the main features for a histopathological diagnosis of IPH.
authors.affiliation: Department of Pathology, China-Japan Friendship Hospital, Beijing, 100029, China.
authors.forename: Xia
authors.initials: X
authors.lastname: Liu
authors.forename: Tai-ling
authors.initials: TL
authors.lastname: Wang
authors.forename: Can-hong
authors.initials: CH
authors.lastname: Xiang
authors.forename: Xiang-xin
authors.initials: XX
authors.lastname: Peng
authors.forename: Yue
authors.initials: Y
authors.lastname: Wang
authors.forename: Nian
authors.initials: N
authors.lastname: Chen
authors.forename: Min
authors.initials: M
authors.lastname: Zhang
mesh_terms: D000293:Adolescent; D000328:Adult; D005260:Female; D005355:Fibrosis / Q000473:pathology; D006801:Humans; D006975:Hypertension, Portal / Q000473:pathology*; D008099:Liver / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D055815:Young Adult