title: Insulin resistance in children with Helicobacter pylori infection.
abstract: We aimed at investigating insulin resistance in children with Helicobacter pylori (H. pylori) infection. Fasting serum insulin and glucose levels were determined in 31 children with H. pylori (+) (H. pylori-infected group, 20 girls and 11 boys, median age 12 yr, range 6-17) and 29 H. pylori (-) (control group, 18 girls and 11 boys, median age 13 yr, range 5-16). Insulin resistance was assessed using homeostasis model assessment of insulin resistance (HOMA-IR) score. Fasting serum glucose levels did not differ significantly between H. pylori (+) and (-) children. Both HOMA-IR score and serum insulin levels were significantly higher in H. pylori-infected compared to control children. The findings of the present study suggested that there is a certain relation between H. pylori infection and insulin resistance in children.
authors.affiliation: Central Laboratory Clinical Biochemistry Unit, Medical Faculty, Akdeniz University, Antalya, Turkey. ozdem@akdeniz.edu.tr
authors.forename: S
authors.initials: S
authors.lastname: Ozdem
authors.forename: M
authors.initials: M
authors.lastname: Akcam
authors.forename: A
authors.initials: A
authors.lastname: Yilmaz
authors.forename: R
authors.initials: R
authors.lastname: Artan
mesh_terms: D000293:Adolescent; D001786:Blood Glucose / Q000378:metabolism; D002648:Child; D002675:Child, Preschool; D005260:Female; D016481:Helicobacter Infections / Q000097:blood* / Q000175:diagnosis; D016480:Helicobacter pylori; D006801:Humans; D007333:Insulin Resistance / Q000502:physiology*; D008297:Male
chemical_list: D001786:Blood Glucose