title: [Hiccup treated by administration of intranasal vinegar].
abstract: A three-year old girl, who had severe cerebral palsy, severe mental retardation, and symptomatic epilepsy, was suffering from intractable hiccup that lasted for more than an hour since she was 2 years and 10 months old when she undertook tracheotomy and laryngotracheal separation. Sometimes this intractable hiccup was followed by respiratory arrest. Although the hiccup was resistant to conventional medications, the nose drops of small amount of vinegar showed a favorable effect on the hiccup. Intranasal vinegar might stimulate dorsal wall of nasopharynx where the pharyngeal branch of the glossopharyngeal nerve, which is thought as an afferent of the reflex arch of hiccup, is distributed. The administration of intranasal vinegar is a safe and handy method to stimulate dorsal wall of nasopharynx. We believe that intranasal vinegar administration could be a useful nonpharmacologic therapy to cease intractable hiccup.
authors.affiliation: Department of Pediatrics, Ibaraki Prefectural University of Health Science, Inashiki, Ibaraki. iwasakin@ipu.ac.jp
authors.forename: Nobuaki
authors.initials: N
authors.lastname: Iwasaki
authors.forename: Hideyo
authors.initials: H
authors.lastname: Kinugasa
authors.forename: Akimitsu
authors.initials: A
authors.lastname: Watanabe
authors.forename: Tomoko
authors.initials: T
authors.lastname: Katagiri
authors.forename: Ryuta
authors.initials: R
authors.lastname: Tanaka
authors.forename: Kenji
authors.initials: K
authors.lastname: Shin
authors.forename: Hideo
authors.initials: H
authors.lastname: Satoh
mesh_terms: D019342:Acetic Acid / Q000008:administration & dosage*; D000281:Administration, Intranasal; D002547:Cerebral Palsy; D002675:Child, Preschool; D004569:Electroencephalography; D005260:Female; D006606:Hiccup / Q000209:etiology* / Q000628:therapy*; D006801:Humans; D008607:Intellectual Disability
chemical_list: D019342:Acetic Acid