title: [Morphological characteristic of labyrinthine zone of rat allantoic placenta after exposure to vibration of industrial frequency].
abstract: The labyrinthine zone of allantoic placenta was studied after dosated exposure to vibration. The study was carried out in pregnant female Wistar rats (n=68). Rats were subjected to short-term vibration from Day 9 to Day 13 and long-term vibration from the Day 9 to Day 18 of pregnancy (taking into account embryogenesis periodization and the development period of extraembryonic organs). Vibration table with fixed parameters (frequency of 32 Hz and acceleration of 50 m/s2) was used. Placental and fetal mass were measured, labyrinthine zone components were evaluated using the morphometric methods, while labyrinthine cord and fetal vessels along Duval's sinus were studied ultrastructurally. Labyrinth was analyzed from the point of view of rapprochement of maternal and fetal bloodstreams. It was found that the exposure to vibration together with the development of compensatory adaptive mechanisms led to chronic placental insufficiency. Experimental group with short-term vibration exposure (Days 9-13) is of particular interest since chronic placental insufficiency in this group should be considered as decompensated.
authors.forename: Iu I
authors.initials: IuI
authors.lastname: Sklianov
authors.forename: T V
authors.initials: TV
authors.lastname: Savel'eva
authors.forename: G M
authors.initials: GM
authors.lastname: Vakulin
mesh_terms: D000482:Allantois / Q000098:blood supply / Q000648:ultrastructure; D000818:Animals; D002908:Chronic Disease; D005260:Female; D008297:Male; D010920:Placenta / Q000098:blood supply / Q000648:ultrastructure*; D021041:Placental Circulation; D010927:Placental Insufficiency / Q000209:etiology / Q000473:pathology; D011247:Pregnancy; D051381:Rats; D017208:Rats, Wistar; D014327:Trophoblasts / Q000648:ultrastructure*; D014732:Vibration / Q000009:adverse effects*