Hyperthyroidism with fibrous dysplasia: an unusual presentation of McCune-Albright syndrome.
McCune-Albright Syndrome (MAS) is a sporadic disorder characterized by a triad of poly/monostotic fibrous dysplasia, café-au-lait macules, and hyperfunctioning endocrinopathies. Hyperthyroidism as a manifestation of endocrine hyperfunction in MAS is uncommon. We report a patient who had polyostotic fibrous dysplasia with multiple pathological fractures and hyperthyroidism. She underwent surgery for hyperthyroidism and received pamidronate therapy with remarkable relief in bone pains and without any new fractures during her subsequent follow up of 3 years.
Bhat
M H
MH
Department of Endocrinology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Bhadada
S
S
Dutta
P
P
Bhansali
A
A
Mittal
B R
BR
D000328:Adult; D019080:Cafe-au-Lait Spots / Q000209:etiology; D005260:Female; D005265:Femoral Neck Fractures / Q000000981:diagnostic imaging / Q000209:etiology; D005358:Fibrous Dysplasia, Monostotic / Q000150:complications / Q000000981:diagnostic imaging; D005359:Fibrous Dysplasia, Polyostotic / Q000150:complications* / Q000000981:diagnostic imaging; D006801:Humans; D006980:Hyperthyroidism / Q000000981:diagnostic imaging / Q000209:etiology*; D011629:Puberty, Precocious / Q000209:etiology; D011877:Radionuclide Imaging; D014463:Ultrasonography