title: Visual vector inversion in the posterior parietal cortex.
abstract: In the antisaccade task, a saccade must be triggered towards the mirror location of a visual target. The neural basis required for this visual vector inversion remains unclear, although neuronal activities reflecting this process have been recorded in the monkey lateral intraparietal area. We examined a patient with a small, right-sided, posterior parietal stroke who complained of difficulty in manipulating visual information. Antisaccades were markedly hypometric rightwards but normal leftwards. Largely unaffected performances in other saccade tasks revealed that visual and motor processing were not significantly affected. Antisaccade inaccuracy could therefore be ascribed to the impairment of visual vector inversion, a processing specifically required in this task. These findings provide the first evidence in humans that visual vector inversion could be an intrinsic property of the posterior parietal cortex.
authors.affiliation: National Institute of Health and Medical Research, Pitie-Salpetriere Hospital, Paris, France.
authors.forename: Thomas
authors.initials: T
authors.lastname: Nyffeler
authors.forename: Sophie
authors.initials: S
authors.lastname: Rivaud-Pechoux
authors.forename: Charles
authors.initials: C
authors.lastname: Pierrot-Deseilligny
authors.forename: Ramata
authors.initials: R
authors.lastname: Diallo
authors.forename: Bertrand
authors.initials: B
authors.lastname: Gaymard
mesh_terms: D000328:Adult; D005133:Eye Movements / Q000502:physiology; D005260:Female; D007839:Functional Laterality / Q000502:physiology; D006801:Humans; D007092:Imagination / Q000502:physiology; D008279:Magnetic Resonance Imaging; D008297:Male; D008568:Memory / Q000502:physiology; D008875:Middle Aged; D010296:Parietal Lobe / Q000503:physiopathology*; D010775:Photic Stimulation; D011597:Psychomotor Performance / Q000502:physiology; D012438:Saccades / Q000502:physiology; D020521:Stroke / Q000503:physiopathology*; D014796:Visual Perception / Q000502:physiology*