title: [The second stage revision for infected total hip arthroplasty using antibiotic-loaded cement prosthesis].
abstract: OBJECTIVE
  To investigate the effect of two-stage revision for infected total hip arthroplasty (THA) using antibiotic-loaded cement prosthesis.
  
  
  METHODS
  From June 1999 to October 2004, 14 patients who admitted for infected primary total hip arthroplasty surgeries were performed revision surgery with antibiotic-loaded cement prosthesis in two-stage. The mean Harris score of pre-operation was 23. In the first stage operation, the following steps were performed, complete debridement, removal of infected prosthesis, implantation of cement spacer with antibiotics, treatment involved concomitant administration of 3 weeks of intravenous (IV) and 1 month of oral. After 6 months, antibiotic-loaded prosthesis was implanted in the second stage.
  
  
  RESULTS
  The mean follow-up was 18 months (7 - 26 months), no recurrent infection occurred in all 14 patients. The mean post-operation Harris score was 70.
  
  
  CONCLUSIONS
  The success of the protocol to control the delayed infection after THA are complete debridement, enough interval and using antibiotic-loaded cement prosthesis in two stage revision.
authors.affiliation: Arthritis Clinic and Research Center, Beijing University People's Hospital, Beijing 100044, China.
authors.forename: Wei
authors.initials: W
authors.lastname: Wei
authors.forename: Bo-Long
authors.initials: BL
authors.lastname: Kou
authors.forename: Rong-Sen
authors.initials: RS
authors.lastname: Ju
authors.forename: Hou-Shan
authors.initials: HS
authors.lastname: Lü
mesh_terms: D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D019644:Arthroplasty, Replacement, Hip / Q000009:adverse effects; D001843:Bone Cements; D005260:Female; D005500:Follow-Up Studies; D006622:Hip Prosthesis; D006801:Humans; D008297:Male; D008875:Middle Aged; D016459:Prosthesis-Related Infections / Q000175:diagnosis / Q000209:etiology / Q000601:surgery*; D012086:Reoperation
chemical_list: D000900:Anti-Bacterial Agents; D001843:Bone Cements