title: Hans von Bülow: creativity and neurological disease in a famous pianist and conductor.
abstract: Hans von Bülow (1830-1894) was a conductor and pianist of worldwide reputation and founder of many stylistic interpretations of classic and romantic symphonies. The close friendship with Richard Wagner, but not the enthusiastic admiration of his dramatic musical opus, ended abruptly when Hans von Bülow became aware of the betrayal of his wife Cosima and Richard Wagner. Hans von Bülow reported symptoms and signs of neurological disease in many letters that were kept and edited by his second wife Marie. For decades he suffered from chronic neuralgiforme headaches, which were caused by a tumor of the cervical radicular nerves. At the age of 45 years, he suddenly developed a motorsensory deficit in the right arm and hand and a contralateral facial deficit, suggestive of brainstem infarction. He recovered and celebrated even greater successes as a musician, although phases of major depression also interfered with his professional life. In the last, phase of his life, he experienced the consequences of generalized atherosclerosis and cerebral microangiopathy. It was a second cerebrovascular accident of the brainstem that caused his death, only 10 months after his last concert performance. Although his death occurred in Egypt, an autopsy was performed by Professor Ludwig Edinger and the results will be presented.
authors.affiliation: Department of Neurology, Katholisches Klinikum, Koblenz,Germany.
authors.forename: Johannes C
authors.initials: JC
authors.lastname: Wöhrle
authors.forename: Frithjof
authors.initials: F
authors.lastname: Haas
mesh_terms: D000223:Adaptation, Psychological; D020526:Brain Stem Infarctions / Q000266:history*; D003405:Creativity; D005858:Germany; D020773:Headache Disorders / Q000266:history; D049672:History, 19th Century; D006801:Humans; D002537:Intracranial Arteriosclerosis / Q000266:history; D008297:Male; D009146:Music / Q000266:history* / Q000523:psychology; D010291:Paresis / Q000266:history; D013315:Stress, Psychological / Q000266:history