title: Methicillin-resistant Staphylococcus aureus osteomyelitis and septic arthritis in neonates: diagnosis and management.
abstract: Acute osteomyelitis (AO) in neonates, although rare, represents a diagnostic and therapeutic challenge. A high index of suspicion is necessary to make an early diagnosis, and the observation of clinical signs is crucial. The increasing prevalence of methicillin-resistant Staphylococcus aureus (MRSA) is an emerging problem in pediatrics. In neonates, MRSA infections can cause a wide spectrum of diseases including bone and joint infections. We report two cases of AO in full-term neonates, with no risk factors, due to MRSA.
authors.affiliation: Department of Neonatology, University of Crete, Heraklin, Greece.
authors.forename: Eftichia
authors.initials: E
authors.lastname: Korakaki
authors.forename: Agisilaos
authors.initials: A
authors.lastname: Aligizakis
authors.forename: Antonia
authors.initials: A
authors.lastname: Manoura
authors.forename: Eleftheria
authors.initials: E
authors.lastname: Hatzidaki
authors.forename: Emmanuel
authors.initials: E
authors.lastname: Saitakis
authors.forename: Maria
authors.initials: M
authors.lastname: Anatoliotaki
authors.forename: Emmanuel
authors.initials: E
authors.lastname: Velivasakis
authors.forename: Sofia
authors.initials: S
authors.lastname: Maraki
authors.forename: Christina
authors.initials: C
authors.lastname: Giannakopoulou
mesh_terms: D000208:Acute Disease; D001170:Arthritis, Infectious / Q000175:diagnosis / Q000382:microbiology* / Q000473:pathology; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007717:Knee / Q000473:pathology; D008297:Male; D016106:Methicillin Resistance; D010019:Osteomyelitis / Q000150:complications* / Q000175:diagnosis / Q000382:microbiology* / Q000473:pathology; D013203:Staphylococcal Infections / Q000175:diagnosis / Q000382:microbiology / Q000473:pathology; D013211:Staphylococcus aureus / Q000187:drug effects*; D013977:Tibia / Q000473:pathology