title: Minimal model of self-replicating nanocells: a physically embodied information-free scenario.
abstract: The building of minimal self-reproducing systems with a physical embodiment (generically called protocells) is a great challenge, with implications for both theory and applied sciences. Although the classical view of a living protocell assumes that it includes information-carrying molecules as an essential ingredient, a dividing cell-like structure can be built from a metabolism-container coupled system only. An example of such a system, modelled with dissipative particle dynamics, is presented here. This article demonstrates how a simple coupling between a precursor molecule and surfactant molecules forming micelles can experience a growth-division cycle in a predictable manner, and analyses the influence of crucial parameters on this replication cycle. Implications of these results for origins of cellular life and living technology are outlined.
authors.affiliation: ICREA-Complex Systems Lab, Universitat Pompeu Fabra (GRIB), Dr Aiguader 80, 08003 Barcelona, Spain.
authors.forename: Harold
authors.initials: H
authors.lastname: Fellermann
authors.forename: Ricard V
authors.initials: RV
authors.lastname: Solé
mesh_terms: D002468:Cell Physiological Phenomena; D003198:Computer Simulation; D008954:Models, Biological; D036103:Nanotechnology