Granular cell tumor of the urethra.
A 38-year-old woman was referred for urethral tumor treatment. Needle biopsy of the tumor was performed. Histologically, the tumor was composed of large polygonal cells with eosinophilic and periodic acid-Schiff (PAS)-positive granular cytoplasm, indistinct cell margins and small round central nuclei. Immunohistochemical staining for S100 protein, vimentin, and neuron-specific enolase (NSE) was positive, indicating that it was a granular cell tumor. Excision of the tumor including the urethra and appendicovesicostomy using the Mitrofanoff principle were performed. There has been no tumor recurrence in the 8 months after the operation.
Yokoyama
Hitoshi
H
Department of Urology, National Matsumoto University, Matsumoto City, Nagano, Japan. h-yokoyama0608@ych.pref.yamanashi.jp
Kontani
Kazuhiko
K
Komiyama
Itsuki
I
Yoneyama
Takehisa
T
Nakazawa
Kou
K
D000328:Adult; D005260:Female; D016586:Granular Cell Tumor / Q000175:diagnosis*; D006801:Humans; D014523:Urethral Neoplasms / Q000175:diagnosis*