Dicamba resistance: enlarging and preserving biotechnology-based weed management strategies.
The advent of biotechnology-derived, herbicide-resistant crops has revolutionized farming practices in many countries. Facile, highly effective, environmentally sound, and profitable weed control methods have been rapidly adopted by crop producers who value the benefits associated with biotechnology-derived weed management traits. But a rapid rise in the populations of several troublesome weeds that are tolerant or resistant to herbicides currently used in conjunction with herbicide-resistant crops may signify that the useful lifetime of these economically important weed management traits will be cut short. We describe the development of soybean and other broadleaf plant species resistant to dicamba, a widely used, inexpensive, and environmentally safe herbicide. The dicamba resistance technology will augment current herbicide resistance technologies and extend their effective lifetime. Attributes of both nuclear- and chloroplast-encoded dicamba resistance genes that affect the potency and expected durability of the herbicide resistance trait are examined.
Behrens
Mark R
MR
Department of Biochemistry, University of Nebraska, Lincoln, NE 68588, USA.
Mutlu
Nedim
N
Chakraborty
Sarbani
S
Dumitru
Razvan
R
Jiang
Wen Zhi
WZ
Lavallee
Bradley J
BJ
Herman
Patricia L
PL
Clemente
Thomas E
TE
Weeks
Donald P
DP
D000383:Agriculture; D017360:Arabidopsis / Q000187:drug effects / Q000235:genetics; D002736:Chloroplasts / Q000235:genetics; D003996:Dicamba / Q000494:pharmacology*; D004351:Drug Resistance / Q000235:genetics; D005818:Genetic Engineering; D005822:Genetic Vectors; D006540:Herbicides / Q000494:pharmacology*; D018551:Solanum lycopersicum / Q000187:drug effects / Q000235:genetics; D006899:Mixed Function Oxygenases / Q000235:genetics* / Q000378:metabolism; D008969:Molecular Sequence Data; D010090:Oxidoreductases, O-Demethylating / Q000378:metabolism; D030821:Plants, Genetically Modified / Q000187:drug effects / Q000235:genetics; D011549:Pseudomonas / Q000201:enzymology / Q000235:genetics; D013025:Glycine max / Q000187:drug effects* / Q000235:genetics; D014026:Nicotiana / Q000187:drug effects / Q000235:genetics
D006540:Herbicides; D006899:Mixed Function Oxygenases; D010090:Oxidoreductases, O-Demethylating; C502811:dicamba O-demethylase; D003996:Dicamba