Composition and alpha-amylase inhibitory effect of essential oils from Cedrus libani.
The inhibitory activity of alpha-amylase and the phytochemical composition of Cedrus libani essential oils obtained from wood, leaves and cones were investigated. The C. libani woods oil exhibit an IC(50) value of 0.14 mg/ml, whereas the leaves and cones oils were devoid of any significant activity.
Loizzo
M R
MR
Department of Pharmaceutical Sciences, University of Calabria, I-87036 Rende (CS), Italy. mr.loizzo@unical.it
Saab
A M
AM
Statti
G A
GA
Menichini
F
F
D028203:Cedrus; D004791:Enzyme Inhibitors / Q000008:administration & dosage / Q000737:chemistry / Q000494:pharmacology* / Q000627:therapeutic use; D006801:Humans; D008517:Phytotherapy; D018515:Plant Leaves; D010938:Plant Oils / Q000008:administration & dosage / Q000737:chemistry / Q000494:pharmacology* / Q000627:therapeutic use; D014934:Wood; D000516:alpha-Amylases / Q000037:antagonists & inhibitors* / Q000187:drug effects*
D004791:Enzyme Inhibitors; D010938:Plant Oils; D000516:alpha-Amylases