title: [Histopathological diagnosis in gastroesophageal reflux disease].
abstract: We reviewed the histopathological features for the diagnosis of gastroesophageal reflux disease (GERD). The presence of infiltration inflammatory cells, thickened basal cell layer, increased papillary height was histopathologically evaluated in GERD patients. It is often difficult to diagnose GERD symptoms when there were few endoscopic findings, such as lack of hiatal hernia and erosive esophagitis. At that time, we might be able to diagnose GERD by the histopathological examination except the pH monitor was performed. We showed that the histopathological esophagitis correlated with reflux symptoms and laryngopharyngeal symptoms. These indicated that the histopathological esophagitis may be diagnosed as not only typical GERD but also atypical GERD.
authors.affiliation: Departments of Internal Medicine and Bioregulation, Nagoya City University Graduate School of Medical Sciences.
authors.forename: Tsuneya
authors.initials: T
authors.lastname: Wada
authors.forename: Makoto
authors.initials: M
authors.lastname: Sasaki
authors.forename: Hiromi
authors.initials: H
authors.lastname: Kataoka
authors.forename: Takeshi
authors.initials: T
authors.lastname: Kamiya
authors.forename: Takasi
authors.initials: T
authors.lastname: Joh
mesh_terms: D001706:Biopsy; D004945:Esophagoscopy; D004947:Esophagus / Q000473:pathology*; D005764:Gastroesophageal Reflux / Q000175:diagnosis* / Q000473:pathology*; D006801:Humans