title: [Cutaneous adverse reaction to Bio-Alcamid implant].
abstract: In the last years new and numerous materials for the correction of defects and wrinkles have been developed. One of these materials is Bio-Alcamid, a non reabsorbable gel polymer constituted by meshes of poly-alkyl-imide, without known adverse effects. We report a 34-year-old woman that had Bio-Alcamid implants for acne scars and several months after presented nodular lesions together with a painful inflammatory nodule. The nodule was drained and culture of the purulent material yielded Streptococcus viridans. A cytology and a cellular block of that material showed a granulomatous inflammatory reaction together with a foreign body. The different types of reactions to implants and their pathogenic mechanism are discussed. It is important to know these possible reactions to filler materials given their increasing use and the potential medico-legal consequences.
authors.affiliation: Unidades de Dermatología, Fundación Hospital Alcorcón, Madrid, España. egomezf@fhalcorcon.es
authors.forename: E
authors.initials: E
authors.lastname: Gómez-de la Fuente
authors.forename: J G
authors.initials: JG
authors.lastname: Alvarez-Fernández
authors.forename: F
authors.initials: F
authors.lastname: Pinedo
authors.forename: E
authors.initials: E
authors.lastname: Naz
authors.forename: R
authors.initials: R
authors.lastname: Gamo
authors.forename: F J
authors.initials: FJ
authors.lastname: Vicente-Martín
authors.forename: J L
authors.initials: JL
authors.lastname: López-Estebaranz
mesh_terms: D000152:Acne Vulgaris / Q000601:surgery; D000180:Acrylic Resins / Q000008:administration & dosage / Q000009:adverse effects*; D000328:Adult; D001672:Biocompatible Materials / Q000008:administration & dosage / Q000009:adverse effects*; D002921:Cicatrix / Q000601:surgery; D005148:Facial Dermatoses / Q000209:etiology*; D005260:Female; D005549:Foreign-Body Reaction / Q000209:etiology*; D006099:Granuloma / Q000209:etiology*; D006801:Humans; D007279:Injections, Subcutaneous; D019736:Prostheses and Implants / Q000009:adverse effects*; D016459:Prosthesis-Related Infections / Q000209:etiology / Q000382:microbiology; D017192:Skin Diseases, Bacterial / Q000209:etiology; D013290:Streptococcal Infections / Q000209:etiology; D034363:Viridans Streptococci / Q000302:isolation & purification
chemical_list: D000180:Acrylic Resins; C470344:Bio-Alcamid; D001672:Biocompatible Materials