title: Integrating partial breast irradiation into surgical practice and clinical trials.
abstract: The use of accelerated partial breast irradiation (APBI) in place of whole-breast irradiation (WBI) for breast-conservation therapy (BCT) is an area of intensive clinical investigation. This article describes evolving methods of APBI in comparison to WBI and in the setting of ongoing clinical trials.
authors.affiliation: The University of Texas M.D. Anderson Cancer Center, Department of Surgical Oncology-Unit#444, 1400 Holcombe Boulevard, #FC.12.3000, Houston, TX 77030, USA.
authors.forename: Regina M
authors.initials: RM
authors.lastname: Fearmonti
authors.forename: Frank A
authors.initials: FA
authors.lastname: Vicini
authors.forename: Timothy M
authors.initials: TM
authors.lastname: Pawlik
authors.forename: Henry M
authors.initials: HM
authors.lastname: Kuerer
mesh_terms: D001918:Brachytherapy / Q000295:instrumentation / Q000379:methods; D001940:Breast / Q000528:radiation effects*; D001943:Breast Neoplasms / Q000532:radiotherapy* / Q000601:surgery; D005260:Female; D006801:Humans; D021621:Imaging, Three-Dimensional; D007430:Intraoperative Care; D015412:Mastectomy, Segmental; D020360:Neoadjuvant Therapy; D020266:Radiotherapy, Conformal / Q000295:instrumentation / Q000379:methods