title: DoriC: a database of oriC regions in bacterial genomes.
abstract: Replication origins (oriCs) of bacterial genomes currently available in GenBank have been predicted by using a systematic method comprising the Z-curve analysis for nucleotide distribution asymmetry, DnaA box distribution, genes adjacent to candidate oriCs and phylogenetic relationships. These oriCs are organized into a MySQL database, DoriC, which provides extensive information and graphical views of the oriC regions. In addition, users can Blast a query sequence or even a whole genome against DoriC to find a homologous one. DoriC will be updated timely and the latest version is DoriC 1.8, in which oriCs of 425 genomes (468 chromosomes) are identified.
  
  
  BACKGROUND
  DoriC can be accessed from http://tubic.tju.edu.cn/doric/.
  
  
  BACKGROUND
  Supplementary data are available at http://tubic.tju.edu.cn/doric/supplementary.htm.
authors.affiliation: Department of Physics, Tianjin University, Tianjin 300072, China.
authors.forename: Feng
authors.initials: F
authors.lastname: Gao
authors.forename: Chun-Ting
authors.initials: CT
authors.lastname: Zhang
mesh_terms: D000465:Algorithms; D001482:Base Composition; D002874:Chromosome Mapping; D002876:Chromosomes, Bacterial; D019295:Computational Biology / Q000379:methods*; D030541:Databases, Genetic; D030561:Databases, Nucleic Acid; D016680:Genome, Bacterial; D020407:Internet; D010802:Phylogeny; D011381:Programming Languages; D018741:Replication Origin; D012984:Software; D048229:Sulfolobus solfataricus / Q000235:genetics