title: Characterization of invasive Haemophilus influenzae disease in Manitoba, Canada, 2000-2006: invasive disease due to non-type b strains.
abstract: In addition to the proportional increase in cases of non-type b Haemophilus influenzae disease in the post-H. influenzae type b vaccine era, the incidence of invasive H. influenzae disease was found to be approaching the rates of H. influenzae type b disease that were documented in the prevaccine period. Fifty-six percent of invasive disease now occurs in individuals aged >10 years.
authors.affiliation: Vaccine Preventable Bacterial Diseases, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Manitoba, Canada. raymond_tsang@phac-aspc.gc.ca
authors.forename: Raymond S W
authors.initials: RS
authors.lastname: Tsang
authors.forename: Michelle L
authors.initials: ML
authors.lastname: Sill
authors.forename: Stuart J
authors.initials: SJ
authors.lastname: Skinner
authors.forename: Dennis K S
authors.initials: DK
authors.lastname: Law
authors.forename: Jianwei
authors.initials: J
authors.lastname: Zhou
authors.forename: John
authors.initials: J
authors.lastname: Wylie
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D002648:Child; D002675:Child, Preschool; D021821:Communicable Diseases, Emerging / Q000145:classification / Q000453:epidemiology; D016021:Epidemiologic Studies; D005260:Female; D006192:Haemophilus Infections / Q000453:epidemiology*; D018073:Haemophilus Vaccines / Q000276:immunology / Q000627:therapeutic use*; D006193:Haemophilus influenzae / Q000145:classification* / Q000472:pathogenicity; D019741:Haemophilus influenzae type b / Q000472:pathogenicity*; D006801:Humans; D015994:Incidence; D007223:Infant; D008297:Male; D008350:Manitoba / Q000453:epidemiology; D008875:Middle Aged; D010865:Pilot Projects; D015995:Prevalence; D012189:Retrospective Studies; D018571:Sentinel Surveillance
chemical_list: D018073:Haemophilus Vaccines