Molecular simulations of rhodopsin tetrameter.
Di/oligomerization of G-protein coupled receptors (GPCRs) is well established, however very little is known regarding the interaction details. Current paper presents results of molecular dynamics simulations of theoretical model of rhodopsin tetramer with transducine (Gt) in lipid bilayer. Ligand-protein and receptor-receptor interactions have been proposed.
Witt
M
M
Faculty of Chemistry, University of Gdansk, ul. Sobieskiego 18, Gdańsk, Poland. ruda@chem.univ.gda.pl
Ciarkowski
J
J
Czaplewski
C
C
D003198:Computer Simulation; D008051:Lipid Bilayers / Q000737:chemistry; D008958:Models, Molecular; D020836:Protein Structure, Quaternary; D012243:Rhodopsin / Q000737:chemistry*; D015293:Transducin / Q000737:chemistry*
D008051:Lipid Bilayers; D012243:Rhodopsin; D015293:Transducin