High levels of CA125 (over 1,000 IU/ml) in patients with gynecologic disease and no malignant conditions: three cases and literature review.
OBJECTIVE
To report the very high serum levels of CA125 in patients with benign gynecologic disease which manifests as pelvic mass.


METHODS
Clinical data of three cases with high levels of CA125 over 1,000 IU/ml and benign gynecologic conditions were gathered. in Vali-Asr hospital.


RESULTS
Three patients were scheduled for laparatomy as ovarian cancer and leiomyosarcoma. Histologic results after laparatomy showed uterine myoma in two patients and endometrioma in a third patient.


CONCLUSIONS
High levels of CA125 over 1,000 IU/ml, may be showed in other gynecologic conditions with no malignancy. So, other clinical and imaging data could be helpful for differential diagnosis of these patients.
Ghaemmaghami
Fatemeh
F
Gynecologic Oncology Department, Vali-e-Asr Hospital, Tehran University of Medical Sciences, Imam Khomeini Hospital Complex, Tehran 14194, Iran.
Karimi Zarchi
Mojgan
M
Hamedi
Bahareh
B
D000328:Adult; D018394:CA-125 Antigen / Q000097:blood*; D003937:Diagnosis, Differential; D016889:Endometrial Neoplasms / Q000097:blood / Q000175:diagnosis* / Q000601:surgery; D004715:Endometriosis / Q000097:blood / Q000175:diagnosis* / Q000601:surgery; D005260:Female; D006801:Humans; D007889:Leiomyoma / Q000097:blood / Q000175:diagnosis* / Q000601:surgery; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000175:diagnosis; D014594:Uterine Neoplasms / Q000097:blood / Q000175:diagnosis* / Q000601:surgery
D018394:CA-125 Antigen