title: Ileal malignant melanoma causing intussusception: report of a case.
abstract: Cutaneous malignant melanoma (MM) often metastasizes to the gastrointestinal (GI) tract; however, primary MM of the small intestine is a controversial diagnosis. We report the case of a 76-year-old woman found to have a primary MM in the ileum. After clinical evaluation, the radiological workup, which included magnetic resonance enteroclysis (MRE), revealed a large polypoid intraluminal tumor. She underwent laparotomy and the lesion was excised. Histological examination of the resected specimen revealed morphological and immunohistochemical characteristics of MM and a detailed postoperative examination failed to identify a primary lesion on the skin, anus, oculus, or any other site. The patient died of brain metastasis 6 months after surgery. According to our review of the literature, this is the first case of primary MM of the small intestine diagnosed with the help of MRE.
authors.affiliation: Department of Gastroenterology, University Hospital, P.O. Box 1352, 71110, Heraklion, Crete, Greece.
authors.forename: Konstantinos
authors.initials: K
authors.lastname: Karmiris
authors.forename: Maria
authors.initials: M
authors.lastname: Roussomoustakaki
authors.forename: Maria
authors.initials: M
authors.lastname: Tzardi
authors.forename: John
authors.initials: J
authors.lastname: Romanos
authors.forename: John
authors.initials: J
authors.lastname: Grammatikakis
authors.forename: Manolis
authors.initials: M
authors.lastname: Papadakis
authors.forename: Maria
authors.initials: M
authors.lastname: Polychronaki
authors.forename: Elias A
authors.initials: EA
authors.lastname: Kouroumalis
mesh_terms: D000368:Aged; D001932:Brain Neoplasms / Q000556:secondary; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007078:Ileal Neoplasms / Q000150:complications* / Q000473:pathology; D007443:Intussusception / Q000209:etiology*; D008545:Melanoma / Q000150:complications* / Q000473:pathology / Q000556:secondary