Positive natural selection has driven the evolution of the Hsp70s in Diguetia spiders.
Hsp70s are a ubiquitous family of highly conserved proteins. Hsp70s are chaperones and have important roles in both protein folding and thermotolerance. It has been widely assumed that Hsp70 sequence evolution is governed by the strong functional constraints imposed by its crucial cellular functions. In this study of cytosolic heat-inducible Hsp70s from three spider families, we have found clear evidence of positive natural selection altering Hsp70s in desert-dwelling and heat-loving Diguetidae spiders. These spiders are a small family restricted to deserts. They display heat-tolerant behaviours not seen in their closest relatives, the Pholcidae and Plectreuridae.
Starrett
James
J
Department of Biology, San Diego State University, San Diego, CA 92182, USA.
Waters
Elizabeth R
ER
D000595:Amino Acid Sequence; D000818:Animals; D003889:Desert Climate; D019143:Evolution, Molecular; D018840:HSP70 Heat-Shock Proteins / Q000235:genetics*; D006358:Hot Temperature; D010802:Phylogeny; D012641:Selection, Genetic; D016415:Sequence Alignment; D017422:Sequence Analysis, DNA; D013112:Spiders / Q000145:classification / Q000235:genetics*
D018840:HSP70 Heat-Shock Proteins