GIRK channels as a target for SSRIs. Focus on "reduced 5-HT1A- and GABAB receptor function in dorsal raphe neurons upon chronic fluoxetine treatment of socially stressed rats".
McGehee
Daniel S
DS
D000818:Animals; D005473:Fluoxetine / Q000627:therapeutic use*; D051676:G Protein-Coupled Inwardly-Rectifying Potassium Channels / Q000502:physiology*; D011903:Raphe Nuclei / Q000187:drug effects* / Q000503:physiopathology; D051381:Rats; D044282:Receptor, Serotonin, 5-HT1A / Q000502:physiology*; D018080:Receptors, GABA-B / Q000502:physiology*; D017367:Selective Serotonin Reuptake Inhibitors / Q000627:therapeutic use*; D013312:Stress, Physiological / Q000188:drug therapy*
D005473:Fluoxetine; D051676:G Protein-Coupled Inwardly-Rectifying Potassium Channels; D044282:Receptor, Serotonin, 5-HT1A; D018080:Receptors, GABA-B; D017367:Selective Serotonin Reuptake Inhibitors