title: A comparison of the activity of tigecycline against multiresistant clinical isolates of Staphylococcus aureus and Streptococcus agalactiae.
abstract: We evaluated the activity of several antibiotics against 225 clinical isolates of Staphylococcus aureus and 252 isolates of Streptococcus agalactiae. Only tigecycline, glycopeptides, and linezolid were active against all the isolates of S. aureus, whereas the beta-lactams were also active against S. agalactiae. Tigecycline could be a good alternative to ampicillin in the treatment of group B Streptococcus infections in patients allergic to beta-lactam.
authors.affiliation: Department of Microbiology, School of Medicine, University of Granada, and San Cecilio University Hospital, Granada, Spain.
authors.forename: Antonio
authors.initials: A
authors.lastname: Sorlozano
authors.forename: Jose
authors.initials: J
authors.lastname: Gutierrez
authors.forename: Eva
authors.initials: E
authors.lastname: Roman
authors.forename: Juan
authors.initials: J
authors.lastname: de Dios Luna
authors.forename: Juan
authors.initials: J
authors.lastname: Roman
authors.forename: Jose
authors.initials: J
authors.lastname: Liebana
authors.forename: Gonzalo
authors.initials: G
authors.lastname: Piedrola
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D024901:Drug Resistance, Multiple, Bacterial; D006801:Humans; D008826:Microbial Sensitivity Tests; D008911:Minocycline / Q000031:analogs & derivatives* / Q000494:pharmacology; D013203:Staphylococcal Infections / Q000382:microbiology; D013211:Staphylococcus aureus / Q000187:drug effects* / Q000302:isolation & purification; D013290:Streptococcal Infections / Q000382:microbiology; D013292:Streptococcus agalactiae / Q000187:drug effects* / Q000302:isolation & purification; D000078304:Tigecycline
chemical_list: D000900:Anti-Bacterial Agents; D000078304:Tigecycline; D008911:Minocycline