title: [Effect of eleutherococcus on hemostasis in immobilized rats].
abstract: The influence of a chronic (30 days) administration of an eleutherococcus extract on the haemostatic system state was studied in immobilized rats. A 3-h immobilization of untreated animals is accompanied by hypercoagulation and thrombinemia signs on the background of downregulation of the anticoagulant and fibrinolytic activity, which leads to a risk of thrombosis. Preliminary 30-day course of eleutherococcus uptake prevents the immobilization-induced thrombosis in rats.
authors.forename: I I
authors.initials: II
authors.lastname: Shakhmatov
authors.forename: Iu A
authors.initials: IuA
authors.lastname: Bondarchuk
authors.forename: V M
authors.initials: VM
authors.lastname: Vdovin
authors.forename: O V
authors.initials: OV
authors.lastname: Alekseeva
authors.forename: V I
authors.initials: VI
authors.lastname: Kiselev
mesh_terms: D000818:Animals; D028001:Eleutherococcus / Q000737:chemistry*; D006487:Hemostasis / Q000187:drug effects*; D007103:Immobilization / Q000009:adverse effects*; D010936:Plant Extracts / Q000627:therapeutic use; D010974:Platelet Aggregation / Q000187:drug effects*; D051381:Rats; D017208:Rats, Wistar; D019851:Thrombophilia / Q000188:drug therapy* / Q000209:etiology
chemical_list: D010936:Plant Extracts