The effects of an individualized exercise intervention on body composition in breast cancer patients undergoing treatment.
OBJECTIVE
Changes in metabolism have been reported in the majority of patients undergoing cancer treatment, and these are usually characterized by progressive change in body composition. The effects of aerobic exercise programs to combat the cancer and cancer treatment-related side effects, which include the negative changes in body composition, have been extensively reported in the literature. However, few resistance exercise intervention studies have hypothesized that breast cancer patients might benefit from this type of exercise. The purpose of this study was to determine whether exercise protocols that emphasize resistance training would change body composition and strength in breast cancer patients undergoing treatment.


METHODS
Randomized controlled trial, at the Campus Recreation Center and Rocky Mountain Cancer Rehabilitation Institute of the University of Northern Colorado, and the North Colorado Medical Center.


METHODS
Twenty inactive breast cancer patients were randomly assigned to a 21-week exercise group (n = 10) or a control group (n = 10). The exercise group trained at low to moderate intensity for 60 minutes on two days/week. The primary outcome measurements included body composition (skinfold method) and muscle strength (one repetition maximum).


RESULTS
Significant differences in lean body mass, body fat and strength (p = 0.004, p = 0.004, p = 0.025, respectively) were observed between the groups at the end of the study.


CONCLUSIONS
The results suggest that exercise emphasizing resistance training promotes positive changes in body composition and strength in breast cancer patients undergoing treatment.
Battaglini
Claudio
C
Department of Exercise and Sport Science, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA. claudio@email.unc.edu
Bottaro
Martim
M
Dennehy
Carolyn
C
Rae
Logan
L
Shields
Edgar
E
Kirk
David
D
Hackney
Anthony Carl
AC
Hackney
Anthony
A
D000273:Adipose Tissue / Q000378:metabolism; D000704:Analysis of Variance; D001823:Body Composition; D001835:Body Weight / Q000502:physiology; D001943:Breast Neoplasms / Q000378:metabolism / Q000534:rehabilitation* / Q000628:therapy; D015444:Exercise / Q000502:physiology*; D005080:Exercise Test / Q000379:methods; D005221:Fatigue / Q000534:rehabilitation; D005260:Female; D006801:Humans; D008875:Middle Aged; D053580:Muscle Strength; D010101:Oxygen Consumption; D011184:Postoperative Period; D012885:Skinfold Thickness; D016896:Treatment Outcome