Atorvastatin is 10-fold more active in vitro than other statins against Plasmodium falciparum.
Pradines
Bruno
B
Torrentino-Madamet
Marylin
M
Fontaine
Albin
A
Henry
Maud
M
Baret
Eric
E
Mosnier
Joel
J
Briolant
Sébastien
S
Fusai
Thierry
T
Rogier
Christophe
C
D000818:Animals; D000962:Antimalarials / Q000494:pharmacology*; D000069059:Atorvastatin; D004305:Dose-Response Relationship, Drug; D006538:Heptanoic Acids / Q000494:pharmacology*; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000494:pharmacology*; D066298:In Vitro Techniques; D020128:Inhibitory Concentration 50; D016778:Malaria, Falciparum / Q000188:drug therapy; D008826:Microbial Sensitivity Tests; D010963:Plasmodium falciparum / Q000187:drug effects* / Q000235:genetics; D011758:Pyrroles / Q000494:pharmacology*; D013329:Structure-Activity Relationship
D000962:Antimalarials; D006538:Heptanoic Acids; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D011758:Pyrroles; D000069059:Atorvastatin