[Relevance of the toxoplasma IgG avidity test in the serological surveillance of pregnant women].
In addition to the serological systematic screening tests, kits to measure the avidity of toxoplasma IgG antibodies are currently available. Since high-avidity IgG toxoplasma antibodies have been shown to exclude recent infection, IgG avidity determination is especially useful in ruling out acute infection having occurred in the 3-4 prior months of pregnancy. We therefore compared the efficacy of two toxoplasma IgG avidity ELISA kits: SFRI (SFRI Laboratoire) and VIDAS Toxo-IgG avidity kit (bioMérieux). The agreement of the results from the 2 commercial assays were analysed using 55 serum samples, in terms of global mother-child Toxoplasma results and outcome, specially with light of the results of Toxoplasma antenatal, postnatal assays and of clinical follow up of children.
Soula
F
F
Service de parasitologie-mycologie, CHRU de Lille - Faculté de Médecine, Université de Lille 2, and Clinique de gynécologie et obstétrique, Hôpital Jeanne de Flandre, France.
Fréalle
E
E
Durand-Joly
I
I
Dutoit
E
E
Rouland
V
V
Renard
E
E
Houfflin-Debarge
V
V
Subtil
D
D
Camus
D
D
Dei-Cas
E
E
Delhaes
L
L
D000818:Animals; D000913:Antibodies, Protozoan / Q000276:immunology*; D000915:Antibody Affinity; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000276:immunology*; D011159:Population Surveillance; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000097:blood*; D011933:Reagent Kits, Diagnostic; D012189:Retrospective Studies; D012698:Serologic Tests / Q000379:methods; D014122:Toxoplasma / Q000276:immunology*; D014123:Toxoplasmosis / Q000097:blood*
D000913:Antibodies, Protozoan; D007074:Immunoglobulin G; D011933:Reagent Kits, Diagnostic