Ocular drug delivery: molecules, cells, and genes.
Recent advances in molecular cell biology have led to the exploration of new therapies based on molecules, cells, and genes to treat a variety of ocular disorders. In this review, we present the current state of knowledge pertaining to the development of different delivery systems to mediate safe and long-lived therapies, with an emphasis on gene therapy. The advantages and limitations of these delivery and therapeutic methods are also discussed.
Liu
Xuyang
X
Department of Ophthalmology and Visual Sciences, University of Wisconsin, Madison 53705-3611, USA.
Brandt
Curtis R
CR
Rasmussen
Carol A
CA
Kaufman
Paul L
PL
D017690:Cell Transplantation / Q000379:methods*; D005128:Eye Diseases / Q000628:therapy*; D018014:Gene Transfer Techniques; D015316:Genetic Therapy / Q000379:methods*; D006801:Humans; D033581:Stem Cell Transplantation / Q000379:methods*