Assessing quality of life in patients with colorectal cancer: an update of the EORTC quality of life questionnaire.
The European Organisation for Research and Treatment of Cancer (EORTC) has a portfolio of questionnaire modules to supplement the QLQ-C30 to assess patient reported outcomes in cancer clinical trials. This study updated the module for colorectal cancer. A review of the literature identified 20 articles that used the EORTC colorectal module. Eight papers did not report data from scales addressing sexual function and 8 added additional scales to assess ano-rectal function. Interviews with patients (n=79) and professionals (n=11) informed item selection, reduction and modification. A new 29 item module was devised and further patient interviews (n=120) examined its format and content validity. Patients found the new module acceptable with relevant content. The new module, the EORTC QLQ-CR29, is hypothesised as containing 6 scales and 11 single items. An international study examining its clinical and psychometric validity will be performed.
Gujral
S
S
United Bristol Healthcare Trust, Clinical Sciences, South Bristol, Level 7, Bristol Royal Infirmary, Marlborough Street, Bristol BS2 8HW, UK.
Conroy
T
T
Fleissner
C
C
Sezer
O
O
King
P M
PM
Avery
K N L
KN
Sylvester
P
P
Koller
M
M
Sprangers
M A G
MA
Blazeby
J M
JM
D000328:Adult; D000368:Aged; D015179:Colorectal Neoplasms / Q000150:complications / Q000523:psychology*; D005260:Female; D006801:Humans; D008297:Male; D017533:Marital Status; D008875:Middle Aged; D010146:Pain / Q000209:etiology; D017060:Patient Satisfaction; D011788:Quality of Life; D012735:Sexual Dysfunction, Physiological / Q000209:etiology; D011795:Surveys and Questionnaires / Q000592:standards*