title: Exuberant molluscum contagiosum as a manifestation of the immune reconstitution inflammatory syndrome.
abstract: Immune reconstitution inflammatory syndrome (IRIS) is a recently described entity in which severely immunodepressed HIV patients, after being started on HAART, develop inflammatory reactions to several pathogens. We present a patient who developed extensive Molluscum Contagiosum (MC) lesions shortly after being started on HAART. With the progression of immunoreconstitution, the lesions healed spontaneously. Molluscum contagiosum lesions are presumably common in IRIS but underreported. We point out this case for its striking clinical picture and well-documented relation to immunoreconstitution to draw attention to this IRIS manifestation.
authors.affiliation: Hospital de Curry Cabral, Dermatology Department, Lisbon, Portugal. barbararosa@hotmail.com
authors.forename: Bárbara
authors.initials: B
authors.lastname: Pereira
authors.forename: Cândida
authors.initials: C
authors.lastname: Fernandes
authors.forename: Ermelinda
authors.initials: E
authors.lastname: Nachiambo
authors.forename: Ma Carmo
authors.initials: MC
authors.lastname: Catarino
authors.forename: Ana
authors.initials: A
authors.lastname: Rodrigues
authors.forename: Jorge
authors.initials: J
authors.lastname: Cardoso
mesh_terms: D000368:Aged; D023241:Antiretroviral Therapy, Highly Active / Q000009:adverse effects* / Q000379:methods; D005500:Follow-Up Studies; D015658:HIV Infections / Q000175:diagnosis / Q000188:drug therapy* / Q000276:immunology; D006681:HLA-D Antigens / Q000276:immunology*; D006801:Humans; D007108:Immune Tolerance; D016867:Immunocompromised Host; D007249:Inflammation / Q000276:immunology* / Q000503:physiopathology / Q000628:therapy; D008297:Male; D008976:Molluscum Contagiosum / Q000139:chemically induced / Q000276:immunology* / Q000628:therapy; D018570:Risk Assessment; D012720:Severity of Illness Index; D013577:Syndrome; D019562:Viral Load
chemical_list: D006681:HLA-D Antigens