Complement hyperactivation may cause atypical haemolytic uraemic syndrome--gain-of-function mutations in factor B.
Caprioli
Jessica
J
Mario Negri Institute for Pharmacological Research, Clinical Research Center for Rare Diseases, Bergamo, Italy. caprioli@marionegri.it
Remuzzi
Giuseppe
G
D003167:Complement Activation / Q000276:immunology*; D011415:Complement Factor B / Q000235:genetics*; D003170:Complement Pathway, Alternative / Q000276:immunology; D006463:Hemolytic-Uremic Syndrome / Q000235:genetics* / Q000276:immunology* / Q000473:pathology; D006801:Humans; D009154:Mutation / Q000235:genetics*
D011415:Complement Factor B