Synthesis of 1,3,4-trisubstituted isoquinolines by iodine-mediated electrophilic cyclization of 2-alkynyl benzyl azides.
Fischer
Dirk
D
Department of Chemistry, Graduate School of Science, Tohoku University, Sendai 980-8578, Japan.
Tomeba
Hisamitsu
H
Pahadi
Nirmal K
NK
Patil
Nitin T
NT
Yamamoto
Yoshinori
Y
D000480:Alkynes / Q000737:chemistry*; D001386:Azides / Q000737:chemistry*; D001554:Benzene / Q000737:chemistry*; D003500:Cyclization; D007455:Iodine / Q000737:chemistry*; D007546:Isoquinolines / Q000138:chemical synthesis* / Q000737:chemistry*; D015394:Molecular Structure
D000480:Alkynes; D001386:Azides; D007546:Isoquinolines; D007455:Iodine; D001554:Benzene