Should I stay or should I go? Nucleocytoplasmic trafficking in plant innate immunity.
Communication between the cytoplasm and the nucleus is a fundamental feature of eukaryotic cells. Bidirectional transport of macromolecules across the nuclear envelope is typically mediated by receptors and occurs exclusively through nuclear pore complexes (NPCs). The components and molecular mechanisms regulating nucleocytoplasmic trafficking and signalling processes are well studied in animals and yeast but are poorly understood in plants. Current work shows that components of the NPC and the nuclear import and export machinery play essential roles in plant innate immunity. Translocation of defence regulators and Resistance (R) proteins between the cytoplasm and the nucleus are recently uncovered aspects of plant defence responses against pathogens. Future studies will reveal more details on the spatial and temporal dynamics and regulation of this process.
Wiermer
Marcel
M
Michael Smith Laboratories, Room 301, 2185 East Mall, University of British Columbia, Vancouver, BC V6T 1Z4, Canada.
Palma
Kristoffer
K
Zhang
Yuelin
Y
Li
Xin
X
D021581:Active Transport, Cell Nucleus; D002467:Cell Nucleus / Q000378:metabolism*; D003593:Cytoplasm / Q000378:metabolism*; D007113:Immunity, Innate; D009685:Nuclear Envelope; D022022:Nuclear Pore / Q000378:metabolism; D009687:Nuclear Proteins / Q000378:metabolism; D010940:Plant Proteins / Q000378:metabolism; D010944:Plants / Q000276:immunology* / Q000378:metabolism / Q000382:microbiology; D015398:Signal Transduction
D009687:Nuclear Proteins; D010940:Plant Proteins