title: A highly alpha-regioselective AgOTf-catalyzed nucleophilic substitution of the Baylis-Hillman acetates with indoles.
abstract: An efficient method for highly alpha-regioselective nucleophilic substitution of the Baylis-Hillman acetates with indoles catalyzed by AgOTf in high yields (72-99%) has been developed. Reductive cyclization of the substitution products furnished the azepinoindole derivatives in good yields (up to 93%).
authors.affiliation: Beijing National Laboratory for Molecular Sciences (BNLMS), Laboratory for Chemical Biology, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100080, China.
authors.forename: Zahid
authors.initials: Z
authors.lastname: Shafiq
authors.forename: Li
authors.initials: L
authors.lastname: Liu
authors.forename: Zhe
authors.initials: Z
authors.lastname: Liu
authors.forename: Dong
authors.initials: D
authors.lastname: Wang
authors.forename: Yong-Jun
authors.initials: YJ
authors.lastname: Chen