title: Cyathusals A, B, and C, antioxidants from the fermented mushroom Cyathus stercoreus.
abstract: Three new polyketide-type antioxidative compounds, cyathusals A (1), B (2), and C (3), and the known pulvinatal (4) were obtained from the fermented mushroom Cyathus stercoreus. The structures of the compounds were characterized on the basis of NMR and mass spectroscopic data. Cyathusals A, B, and C and pulvinatal showed free radical scavenging activities on the 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical with EC50 values of 41.6, 46.0, 26.6, and 28.6 microM, respectively, and on the 2,2'-azinobis(3-ethylbenzothiazoline-6-sulfonate) (ABTS) cation radical with EC50 values of 7.9, 11.1, 9.1, and 8.4 microM, respectively.
authors.affiliation: KRIBB, 52 Eoeun-dong, Yuseong, Daejeon 305-806, Korea.
authors.forename: Hahk-Soo
authors.initials: HS
authors.lastname: Kang
authors.forename: Eun-Mi
authors.initials: EM
authors.lastname: Jun
authors.forename: Soon-Hye
authors.initials: SH
authors.lastname: Park
authors.forename: Soo-Jin
authors.initials: SJ
authors.lastname: Heo
authors.forename: Tae-Soo
authors.initials: TS
authors.lastname: Lee
authors.forename: Ick-Dong
authors.initials: ID
authors.lastname: Yoo
authors.forename: Jong-Pyung
authors.initials: JP
authors.lastname: Kim
mesh_terms: D000363:Agaricales / Q000737:chemistry*; D000975:Antioxidants / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D001713:Biphenyl Compounds; D005285:Fermentation; D016166:Free Radical Scavengers / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D006575:Heterocyclic Compounds, 3-Ring / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D007723:Korea; D019906:Nuclear Magnetic Resonance, Biomolecular; D010851:Picrates / Q000494:pharmacology
chemical_list: D000975:Antioxidants; D001713:Biphenyl Compounds; D016166:Free Radical Scavengers; D006575:Heterocyclic Compounds, 3-Ring; D010851:Picrates; C521648:cyathusal B; C004931:1,1-diphenyl-2-picrylhydrazyl; C521647:cyathusal C; C521646:cyathusal A