title: Treatment consideration and manifest complexity in comorbid neuropsychiatric disorders.
abstract: Psychiatric disorders may co-occur in the same individual. These include, for example, substance abuse or obsessive-compulsive disorder with schizophrenia, and movement disorders or epilepsy with affective dysfunctional states. Medications may produce iatrogenic effects, for example cognitive impairments that co-occur with the residual symptoms of the primary disorder being treated. The observation of comorbid disorders in some cases may reflect diagnostic overlap. Impulsivity, impulsiveness or impulsive behaviour is implicated in a range of diagnostic conditions including substance abuse, affective disorder and obsessive-compulsive disorder. These observations suggest a need to re-evaluate established diagnostic criteria and disorder definitions, focusing instead on symptoms and symptom-profiles.
authors.affiliation: Psychiatry Service, 12 de Octubre, University Hospital, Madrid 28041, Spain.
authors.forename: Tomas
authors.initials: T
authors.lastname: Palomo
authors.forename: Richard M
authors.initials: RM
authors.lastname: Kostrzewa
authors.forename: Richard J
authors.initials: RJ
authors.lastname: Beninger
authors.forename: Trevor
authors.initials: T
authors.lastname: Archer
mesh_terms: D015897:Comorbidity; D006801:Humans; D007049:Iatrogenic Disease; D007175:Impulsive Behavior / Q000453:epidemiology; D001523:Mental Disorders / Q000453:epidemiology* / Q000628:therapy*; D009069:Movement Disorders / Q000453:epidemiology* / Q000628:therapy; D009422:Nervous System Diseases / Q000453:epidemiology* / Q000628:therapy*; D009771:Obsessive-Compulsive Disorder / Q000453:epidemiology; D010551:Personality; D015995:Prevalence; D012559:Schizophrenia / Q000453:epidemiology