title: Disseminated toxoplasmosis presenting as sepsis in two AIDS patients.
abstract: This report describes two patients who presented acute disseminated and severe toxoplasmosis as the first opportunistic disease related to acquired immunodeficiency syndrome. At admission, clinical and laboratory findings were similar to sepsis or septic shock and a fast evolutive course to death occurred in both cases. At necropsy, an inflammatory reaction and presence of a great number of Toxoplasma gondii cysts and tachyzoites were observed in most organs examined.
authors.affiliation: Disciplina de Doenças Infecciosas e Parasitárias, Universidade Federal do Triângulo Mineiro, Uberaba, MG, Brazil.
authors.forename: Carlos José Dornas Gonçalves
authors.initials: CJ
authors.lastname: Barbosa
authors.forename: Rodrigo Juliano
authors.initials: RJ
authors.lastname: Molina
authors.forename: Murilo Barcelos
authors.initials: MB
authors.lastname: de Souza
authors.forename: Ana Cristina A
authors.initials: AC
authors.lastname: Silva
authors.forename: Adilha Rua
authors.initials: AR
authors.lastname: Micheletti
authors.forename: Marlene Antonia
authors.initials: MA
authors.lastname: dos Reis
authors.forename: Vicente
authors.initials: V
authors.lastname: de Paula Antunes Teixeira
authors.forename: Mario León
authors.initials: ML
authors.lastname: Silva-Vergara
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000175:diagnosis* / Q000469:parasitology / Q000473:pathology; D000208:Acute Disease; D000328:Adult; D000818:Animals; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D018805:Sepsis / Q000175:diagnosis* / Q000473:pathology; D012720:Severity of Illness Index; D014122:Toxoplasma / Q000302:isolation & purification; D014123:Toxoplasmosis / Q000175:diagnosis* / Q000473:pathology