title: [Oral involvement in lymphomatoid papulosis].
abstract: Lymphomatoid papulosis is a cutaneous lymphoma with an indolent clinical behaviour characterized by chronic development of recurrent, self-limited lesions appearing as necrotic papules and with a pathology compatible with T cell lymphoma. Mucosal involvement by lymphomatoid papulosis is very rare but has been reported in the literature. It usually appears as ulcers in patients previously diagnosed of lymphomatoid papulosis. From a histological perspective it is characterized by an infiltrate of CD 30 positive atypical lymphocytes together with a mixed inflammatory infiltrate of eosinophils, neutrophils, histiocytes and plasma cells. We report the case of a man previously diagnosed of lymphomatoid papulosis that developed two ulcerated lesions in the tongue whose biopsy confirmed the diagnosis of oral involvement by lymphomatoid papulosis.
authors.affiliation: Servicio de Dermatología, Instituto Valenciano de Oncología, Valencia, España. cserraguillen@hotmail.com
authors.forename: C
authors.initials: C
authors.lastname: Serra-Guillén
authors.forename: C
authors.initials: C
authors.lastname: Requena
authors.forename: A
authors.initials: A
authors.lastname: Alfaro
authors.forename: L
authors.initials: L
authors.lastname: Hueso
authors.forename: O
authors.initials: O
authors.lastname: Sanmartín
authors.forename: B
authors.initials: B
authors.lastname: Llombart
authors.forename: E
authors.initials: E
authors.lastname: Nagore
authors.forename: R
authors.initials: R
authors.lastname: Botella-Estrada
authors.forename: A
authors.initials: A
authors.lastname: Martorell-Calatayud
authors.forename: C
authors.initials: C
authors.lastname: Guillén
mesh_terms: D000368:Aged; D002990:Clobetasol / Q000627:therapeutic use; D004802:Eosinophilia / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology; D006801:Humans; D017731:Lymphomatoid Papulosis / Q000188:drug therapy / Q000473:pathology*; D008297:Male; D008727:Methotrexate / Q000627:therapeutic use; D009061:Mouth Mucosa / Q000473:pathology*; D011241:Prednisone / Q000627:therapeutic use; D014060:Tongue Diseases / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology; D014456:Ulcer / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology
chemical_list: D002990:Clobetasol; D011241:Prednisone; D008727:Methotrexate