BioMoby web services to support clustering of co-regulated genes based on similarity of promoter configurations.
Here we present a computational protocol to analyze the promoter regions of a given set of co-expressed genes, and its implementation through the use of Web services technologies. This protocol aims to cluster a set of co-regulated genes in subsets of genes showing similar configurations of transcription factor binding sites. All the steps of this protocol have been developed as web services that are compliant with BioMoby specifications.


BACKGROUND
{http://genome.imim.es/cgi-bin/moby/GeneClustering_DataSubmission.cgi}.


BACKGROUND
Supplementary data are available at {http://genome.imim.es/webservices/}
Kerhornou
Arnaud
A
Centre de Regulacio Genomica, Institut Municipal d'Investigació Mèdica and Universitat Pompeu Fabra, Pg. Maritim de la Barceloneta, 08003 Barcelona, Catalonia, Spain. arnaud.kerhornou@crg.es
Guigó
Roderic
R
D000465:Algorithms; D001331:Automation; D001665:Binding Sites; D016000:Cluster Analysis; D019295:Computational Biology / Q000379:methods*; D030541:Databases, Genetic; D020869:Gene Expression Profiling; D005786:Gene Expression Regulation; D020407:Internet; D008957:Models, Genetic; D011401:Promoter Regions, Genetic; D012984:Software; D014157:Transcription Factors / Q000378:metabolism
D014157:Transcription Factors