title: Patch repair of ileoanal pouch-vaginal fistula with Permacol collagen implant.
abstract: Though uncommon, ileoanal pouch-vaginal fistulas after restorative proctocolectomy present quite a challenge. Multiple salvage procedures, including endoanal, transabdominal, and trans-vaginal, have been used. Because of high recurrence rates, multiple operations are not uncommon, and ultimate pouch failure rates have been reported as high as 45 per cent. The Permacol Collagen Implant is a surgical implant that has been used successfully in a variety of operations ranging from urological to maxillofacial. Its properties allow fibroblast infiltration and revascularization so that it gradually becomes permanently incorporated into the surrounding tissue, providing strength and inhibiting scarring and contraction. We report the first documented case of Permacol use in repair of ileoanal pouch-vaginal fistula and we feel that it warrants further investigation as an option in the treatment of these fistulas.
authors.affiliation: Department of Surgery, Medical College of Georgia, Augusta, Georgia 30912, USA.
authors.forename: Maurice
authors.initials: M
authors.lastname: Smith
authors.forename: Vendie H
authors.initials: VH
authors.lastname: Hooks
authors.forename: Barry
authors.initials: B
authors.lastname: Jenkins
mesh_terms: D000328:Adult; D001672:Biocompatible Materials / Q000627:therapeutic use*; D003094:Collagen / Q000627:therapeutic use*; D039021:Colonic Pouches; D005260:Female; D006801:Humans; D016737:Proctocolectomy, Restorative / Q000009:adverse effects*; D013536:Suture Techniques; D014624:Vaginal Fistula / Q000209:etiology* / Q000628:therapy*
chemical_list: D001672:Biocompatible Materials; C422414:Permacol; D003094:Collagen