Tuberous sclerosis.
A 46-year-old woman presented with multiple, skin-colored, hyperpigmented, dome-shaped facial papules. Histopathologic examination was consistent with angiofibromas. Clinical history and examination were consistent with tuberous sclerosis. The clinical manifestations, pathogenesis, evaluation, and treatment of tuberous sclerosis are discussed.
Wee
Sue Ann
SA
New York University Department of Dermatology, USA.
Fangman
Bill
B
D001706:Biopsy; D003937:Diagnosis, Differential; D005260:Female; D005624:Frontal Bone / Q000000981:diagnostic imaging; D020022:Genetic Predisposition to Disease; D006801:Humans; D007765:Lacrimal Apparatus / Q000473:pathology; D008875:Middle Aged; D012867:Skin / Q000473:pathology; D014057:Tomography, X-Ray Computed; D014402:Tuberous Sclerosis / Q000175:diagnosis* / Q000235:genetics