title: Cardiovascular fitness and vascular inflammatory markers after acute aerobic exercise.
abstract: Inflammatory markers such as C-reactive protein (CRP), fibrinogen, and white-blood-cell (WBC) count are strongly associated with cardiovascular disease. The authors' purpose was to compare the inflammatory response to a single aerobic-exercise session between individuals of high and moderate fitness. Ten apparently healthy highly fit and 11 moderately fit men expended 500 kcal at 70% of VO2peak. Fasting blood samples were obtained on 2 consecutive days before and again at 24, 72, and 120 h postexercise. Blood samples were analyzed for CRP, fibrinogen, and WBC count. CRP was 76% lower at baseline in the highly fit group than in the moderately fit group (P = 0.03). CRP, fibrinogen, and WBC count remained unaltered, however, in the days after exercise (P > 0.05 for all). These findings suggest that markers of inflammation are stable in the days after a single session of moderate-intensity aerobic exercise in apparently healthy men of at least average fitness.
authors.affiliation: Dept of Health and Human Performance, Auburn University, Auburn, AL 36849, USA.
authors.forename: Eric P
authors.initials: EP
authors.lastname: Plaisance
authors.forename: J Kyle
authors.initials: JK
authors.lastname: Taylor
authors.forename: Sofiya
authors.initials: S
authors.lastname: Alhassan
authors.forename: Asheber
authors.initials: A
authors.lastname: Abebe
authors.forename: Michael L
authors.initials: ML
authors.lastname: Mestek
authors.forename: Peter W
authors.initials: PW
authors.lastname: Grandjean
mesh_terms: D000328:Adult; D015415:Biomarkers / Q000097:blood; D002097:C-Reactive Protein / Q000032:analysis / Q000378:metabolism*; D002318:Cardiovascular Diseases / Q000097:blood / Q000209:etiology; D015444:Exercise / Q000502:physiology*; D005340:Fibrinogen / Q000032:analysis / Q000378:metabolism*; D006304:Health Status; D006801:Humans; D007249:Inflammation / Q000097:blood*; D007958:Leukocyte Count; D008297:Male; D008875:Middle Aged; D010101:Oxygen Consumption; D010809:Physical Fitness / Q000502:physiology*; D012307:Risk Factors; D013997:Time Factors
chemical_list: D015415:Biomarkers; D005340:Fibrinogen; D002097:C-Reactive Protein