[Properties of lung surfactant during changes in capsaicin-sensitive vagal afferents under conditions of emotional stress].
In this work, we investigated surface active properties and biochemical composition of pulmonary surfactant under emotional stress in condition of neuropeptides pool exhaustion in capsaicin-sensitive afferents of the vagus nerve. It is shown that stress is accompanied by decrease of lung surface active properties and increase of total phospholipids content as result of phosphatidylcholine and lysophospholipid fraction rise. After capsaicin application on the cervical part of the right vagus nerve stress-induced alterations in ipsilateral lung become less considerable, whereas all spectra of changes in contralateral lung is remained.
Bryndina
I G
IG
Isaeva
V L
VL
Zorina
M V
MV
D000818:Animals; D002211:Capsaicin / Q000494:pharmacology*; D008168:Lung / Q000294:innervation; D008246:Lysophospholipids / Q000032:analysis; D008297:Male; D009475:Neurons, Afferent / Q000737:chemistry / Q000187:drug effects / Q000378:metabolism*; D009479:Neuropeptides / Q000378:metabolism*; D010713:Phosphatidylcholines / Q000032:analysis; D011663:Pulmonary Surfactants / Q000737:chemistry* / Q000378:metabolism; D051381:Rats; D013315:Stress, Psychological / Q000378:metabolism*; D013499:Surface Properties; D014630:Vagus Nerve / Q000737:chemistry / Q000187:drug effects / Q000378:metabolism*
D008246:Lysophospholipids; D009479:Neuropeptides; D010713:Phosphatidylcholines; D011663:Pulmonary Surfactants; D002211:Capsaicin