[The prognosis and risk factors of cardiovascular complications in patients with chronic glomerulonephritis].
The authors evaluated 10-year prognosis according to SCORE scale and risk factors of fatal cardiovascular diseases in 90 Eropoids aged 53.9+/-0.6 years with a valid diagnosis of chronic glomerulonephritis (CGN) and normal renal function or at the pre-dialysis stage of chronic renal failure. The study found that 34.4% of CGN patients were at high risk of severe complications of atherosclerosis with unfavorable prognosis (myocardial infarctions, cerebral stroke etc.) The leading risk factors of fatal cardiovascular complications in middle-age and elderly CGN patients were male sex, age more than 55 years, smoking, and severe systolic and diastolic arterial hypertension. Patients with IIb phenotype hyperlipidemia and those with selective decrease in high density lipoprotein cholesterol are at significantly higher risk of cardiovascular events.
Mukasheva
S B
SB
Movchan
E A
EA
D002318:Cardiovascular Diseases / Q000209:etiology* / Q000401:mortality; D005260:Female; D005921:Glomerulonephritis / Q000150:complications*; D006801:Humans; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D011379:Prognosis; D012307:Risk Factors