title: The conservation relevance of epidemiological research into carnivore viral diseases in the serengeti.
abstract: Recent outbreaks of rabies and canine distemper in wildlife populations of the Serengeti show that infectious disease constitutes a significant cause of mortality that can result in regional extirpation of endangered species even within large, well-protected areas. Nevertheless, effective management of an infectious disease depends critically on understanding the epidemiological dynamics of the causative pathogen. Pathogens with short infection cycles cannot persist in small populations in the absence of a more permanent reservoir of infection. Development of appropriate interventions requires detailed data on transmission pathways between reservoirs and wildlife populations of conservation concern. Relevant data can be derived from long-term population monitoring, epidemic and case-surveillance patterns, genetic analyses of rapidly evolving pathogens, serological surveys, and intervention studies. We examined studies of carnivore diseases in the Serengeti. Epidemiological research contributes to wildlife conservation policy in terms of management of endangered populations and the integration of wildlife conservation with public health interventions. Long-term, integrative, cross-species research is essential for formulation of effective policy for disease control and optimization of ecosystem health.
authors.affiliation: Wildlife and Emerging Diseases Section, Centre for Tropical Veterinary Medicine, Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush, Roslin, Midlothian, EH25 9RG, United Kingdom. sarah.cleaveland@ed.ac.uk
authors.forename: Sarah
authors.initials: S
authors.lastname: Cleaveland
authors.forename: Titus
authors.initials: T
authors.lastname: Mlengeya
authors.forename: Magai
authors.initials: M
authors.lastname: Kaare
authors.forename: Dan
authors.initials: D
authors.lastname: Haydon
authors.forename: Tiziana
authors.initials: T
authors.lastname: Lembo
authors.forename: M Karen
authors.initials: MK
authors.lastname: Laurenson
authors.forename: Craig
authors.initials: C
authors.lastname: Packer
mesh_terms: D000818:Animals; D000835:Animals, Wild / Q000821:virology*; D003247:Conservation of Natural Resources; D004216:Distemper / Q000453:epidemiology / Q000517:prevention & control / Q000635:transmission* / Q000821:virology; D004285:Dogs / Q000821:virology*; D005260:Female; D008045:Lions / Q000821:virology*; D008297:Male; D011818:Rabies / Q000453:epidemiology / Q000517:prevention & control / Q000635:transmission* / Q000662:veterinary; D013636:Tanzania / Q000453:epidemiology; D014611:Vaccination