Serologic evidence for regional differences in pediatric cryptococcal infection.
Cryptococcus neoformans is present in areas contaminated with pigeon droppings. Unrecognized infections are hypothesized to occur commonly among immunocompetent individuals. We used serology to estimate prevalence of cryptococcal infection in immunocompetent children from 3 regions. Our results indicate unrecognized cryptococcal infections are extremely common in Bronx children, but uncommon in children from Dutchess County, NY and the Philippines.
Davis
Jennifer
J
Department of Pediatrics, Childrens Hospital at Montefiore, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
Zheng
Wang Yong
WY
Glatman-Freedman
Aharona
A
Ng
Josephine Anne Navoa
JA
Pagcatipunan
Marimel R
MR
Lessin
Herschel
H
Casadevall
Arturo
A
Goldman
David L
DL
D000293:Adolescent; D000328:Adult; D000908:Antibodies, Fungal / Q000097:blood; D002648:Child; D002675:Child, Preschool; D003453:Cryptococcosis / Q000453:epidemiology* / Q000276:immunology / Q000473:pathology; D003454:Cryptococcus / Q000276:immunology; D005260:Female; D006801:Humans; D015151:Immunoblotting; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D009518:New York / Q000453:epidemiology; D010679:Philippines / Q000453:epidemiology; D015995:Prevalence; D016036:Seroepidemiologic Studies
D000908:Antibodies, Fungal