Two new dialkoxycarbonylated nucleosides obtained through a regioselective enzymatic alcoholysis.
Two new compounds, 2',3'-di-O-ethoxycarbonyluridine and 2',3'-di-O-ethoxycarbonylinosine, were obtained through a Candida antarctica lipase B catalysed regioselective ethanolysis of the corresponding trialcoxycarbonylated nucleosides with benzyl alcohol in 1,4-dioxane at 30 degrees C.
Capello
Mariana
M
Universidad Nacional de Quilmes, Roque Sáenz Peña 352, 1876, Bernal, The Province of Buenos Aires, Argentina.
Imanishi
Leandro
L
Iglesias
Luis E
LE
Iribarren
Adolfo M
AM
D000438:Alcohols / Q000737:chemistry*; D002175:Candida / Q000201:enzymology*; D002384:Catalysis; D019295:Computational Biology / Q000379:methods*; D004146:Dioxanes / Q000737:chemistry; D004798:Enzymes / Q000737:chemistry; D005656:Fungal Proteins; D008049:Lipase / Q000737:chemistry; D008956:Models, Chemical; D009705:Nucleosides / Q000737:chemistry*; D013237:Stereoisomerism; D013379:Substrate Specificity; D013696:Temperature
D000438:Alcohols; D004146:Dioxanes; D004798:Enzymes; D005656:Fungal Proteins; D009705:Nucleosides; D008049:Lipase; C431349:lipase B, Candida antarctica; C025223:1,4-dioxane