Structural identification of trace level enol tautomer impurity by on-line hydrogen/deuterium exchange HR-LC/MS in a LTQ-Orbitrap hybrid mass spectrometer.
Chen
Guodong
G
Khusid
Anatoliy
A
Daaro
Ibrahim
I
Irish
Patrick
P
Pramanik
Birendra N
BN
D002138:Calibration; D002851:Chromatography, High Pressure Liquid; D003903:Deuterium / Q000737:chemistry; D004340:Drug Contamination; D006859:Hydrogen / Q000737:chemistry; D013058:Mass Spectrometry; D009862:Online Systems; D004364:Pharmaceutical Preparations / Q000032:analysis*; D013056:Spectrophotometry, Ultraviolet; D017550:Spectroscopy, Fourier Transform Infrared
D004364:Pharmaceutical Preparations; D006859:Hydrogen; D003903:Deuterium