Genetic counseling and presenilin-1 Alzheimer's disease: "Research Family" members share some thoughts.
Genetic counseling is a 2-way street between counselor and the counseled. In this article, both share experiences gained through more than 25 years of searching for the gene, finding the presenilin-1 Alzheimer's disease gene, and waiting for a cure. "Research Families" made research models a reality. Few family members requested presymptomatic testing.
Nee
Linda E
LE
Family Studies Unit, National Institute of Neurological Disorders and Stroke, Bethesda, MD 20892, USA. neel@mail.nih.gov
D000328:Adult; D000368:Aged; D000544:Alzheimer Disease / Q000235:genetics* / Q000473:pathology; D001921:Brain / Q000473:pathology; D005260:Female; D005817:Genetic Counseling; D005820:Genetic Testing; D006801:Humans; D008875:Middle Aged; D009154:Mutation; D010375:Pedigree; D053764:Presenilin-1 / Q000235:genetics*
C508853:PSEN1 protein, human; D053764:Presenilin-1