[Detection of Helicobacter pylori in oral cavity of patients with recurrent aphthous ulcer].
OBJECTIVE
To investigate the association of recurrent aphthous ulcer (RAU) with Helicobacter pylori (Hp) infection and digestive diseases.


METHODS
Saliva samples were collected from 82 patients with RAU and 74 healthy volunteers for Hp detection with PCR.


RESULTS
The positivity rates of HP differed significantly between RAU patients and healthy volunteers (43.9% vs 16.2%, P<0.001). In the 82 RAU patients, 22 (26.82%) were identified to have gastritis and peptic ulcer, whereas only 7 out of the 74 healthy volunteers (10.45%) had such digestive diseases, showing significant difference between them (P<0.01).


CONCLUSIONS
Hp might in some way associate with RAU, which in turn is associated with an increased incidence of digestive diseases.
Long
Bao-jun
BJ
Department of Stomatology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
Chen
Ke
K
Wu
Bu-ling
BL
Duan
Jian-min
JM
D000328:Adult; D016022:Case-Control Studies; D005260:Female; D005756:Gastritis / Q000382:microbiology; D016481:Helicobacter Infections / Q000175:diagnosis*; D016480:Helicobacter pylori / Q000302:isolation & purification*; D006801:Humans; D008297:Male; D009055:Mouth / Q000382:microbiology*; D010437:Peptic Ulcer / Q000382:microbiology; D016133:Polymerase Chain Reaction; D012008:Recurrence; D012463:Saliva / Q000382:microbiology; D013281:Stomatitis, Aphthous / Q000382:microbiology*