title: Peratrial closure of atrial septal defects without cardiopulmonary bypass.
abstract: The objective of this study was to introduce a new technique for occlusion of an atrial septal defect without cardiopulmonary bypass, using a modified Amplatzer device. Between October 2004 and November 2005, 96 secundum atrial septal defects in 83 patients were occluded by this method. A 3-cm incision in the right 4(th) intercostal space and a minithoracotomy were performed. Via this incision, the right atrium was exposed and the septal closure device was deployed under transesophageal echocardiographic guidance. The sizes of the defects ranged from 10 to 39 mm. The mean device size was 34.1 +/- 9 mm (12-46 mm). There was no operative mortality and no major morbidity on follow-up of 3-15 months. This new minimally invasive method of secundum atrial septal defect closure is safe and cosmetically superior to conventional surgery. Avoidance of cardiopulmonary bypass can reduce recovery time and complications. The indications are more extensive than percutaneous transcatheter closure, and the results are encouraging.
authors.affiliation: Wuhan Asia Heart Hospital, Wuhan, China. zengxiangjun@sohu.com
authors.forename: Xiang-Jun
authors.initials: XJ
authors.lastname: Zeng
authors.forename: Xu-Fa
authors.initials: XF
authors.lastname: Chen
authors.forename: Duan
authors.initials: D
authors.lastname: Cheng
authors.forename: Xiao-Jing
authors.initials: XJ
authors.lastname: Ma
authors.forename: Xue-Song
authors.initials: XS
authors.lastname: Hu
authors.forename: Liang
authors.initials: L
authors.lastname: Tao
mesh_terms: D000293:Adolescent; D000328:Adult; D006348:Cardiac Surgical Procedures / Q000009:adverse effects / Q000295:instrumentation; D002315:Cardiopulmonary Bypass / Q000009:adverse effects; D002648:Child; D002675:Child, Preschool; D017548:Echocardiography, Transesophageal; D004867:Equipment Design; D005260:Female; D005500:Follow-Up Studies; D006344:Heart Septal Defects, Atrial / Q000000981:diagnostic imaging / Q000401:mortality / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D019060:Minimally Invasive Surgical Procedures; D013908:Thoracotomy / Q000379:methods; D013997:Time Factors; D016896:Treatment Outcome; D018084:Ultrasonography, Interventional