Primary paraspinal leiomyosarcoma invading the cervical spinal canal successfully treated with surgery, radiotherapy, and chemotherapy. Case report.
A primary paraspinal leiomyosarcoma invading the spine is an exceedingly rare neoplasm that may clinically mimic a schwannoma. The authors report a case involving a 45-year-old man with a primary leiomyosarcoma of the cervical paraspinal musculature that invaded the spinal canal at C1-2 and subsequently metastasized to the lungs and pancreas. Aggressive treatment consisting of resection of the primary tumor, adjunctive radiation therapy and chemotherapy, and surgical debulking of metastatic disease resulted in local tumor control at the primary site and long-term survival of the patient.
Lehman
Norman L
NL
Department of Pathology, Stanford University Medical Center, Stanford, California 94305, USA. nlehman@stanford.edu
Jacobs
Charlotte D
CD
Holsten
Phillip A
PA
Jaikumar
Sivakumar
S
Lehman
Trang D
TD
Gibbs
Iris C
IC
Shuer
Lawrence M
LM
D002574:Cervical Vertebrae / Q000473:pathology; D003131:Combined Modality Therapy; D006801:Humans; D007890:Leiomyosarcoma / Q000473:pathology / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D013115:Spinal Canal / Q000473:pathology; D013125:Spinal Neoplasms / Q000473:pathology / Q000628:therapy*