title: Treatment of canine pediatric Neospora caninum myositis following immunohistochemical identification of tachyzoites in muscle biopsies.
abstract: A 7-week-old Irish wolfhound was evaluated for an abnormal hind limb gait. Quadriceps muscle atrophy was pronounced and patellar reflexes were absent bilaterally. Neospora caninum myositis was diagnosed by histopathologic and serologic examination and immunohistochemical staining of muscle. Substantial clinical improvement was noted after 18 weeks of treatment with clindamycin.
authors.affiliation: Western College of Veterinary Medicine, University of Saskatchewan, 52 Campus Drive, Saskatoon, Saskatchewan S7N 5B4.
authors.forename: Jennifer L
authors.initials: JL
authors.lastname: Crookshanks
authors.forename: Susan M
authors.initials: SM
authors.lastname: Taylor
authors.forename: Deborah M
authors.initials: DM
authors.lastname: Haines
authors.forename: G Diane
authors.initials: GD
authors.lastname: Shelton
mesh_terms: D000818:Animals; D000831:Animals, Newborn; D002981:Clindamycin / Q000627:therapeutic use*; D003048:Coccidiosis / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology / Q000662:veterinary*; D003049:Coccidiostats / Q000627:therapeutic use*; D004283:Dog Diseases / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology*; D004285:Dogs; D005260:Female; D007794:Lameness, Animal / Q000209:etiology; D018482:Muscle, Skeletal / Q000469:parasitology; D009220:Myositis / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology / Q000662:veterinary*; D018688:Neospora / Q000302:isolation & purification; D016896:Treatment Outcome
chemical_list: D003049:Coccidiostats; D002981:Clindamycin