title: Major elective surgery for vascular disease in patients aged 80 or more: perioperative (30-day) outcomes.
abstract: Although major vascular surgery is performed with increasing frequency in elderly people, the impact of age on outcomes is uncertain. We evaluated the perioperative (30-day) outcomes for patients who underwent major elective vascular operations under general or peripheral anesthesia in their eighties and nineties in a 14-year period. Data for all consecutive 3,060 patients (456 of them > or years old) who underwent 3,314 elective vascular surgery procedures were prospectively entered into a computerized vascular registry. Detailed information was collected on patients' preoperative status, type of procedure and anesthesia, perioperative outcomes, and predictors of perioperative outcomes. The end points of the study were perioperative death and main surgical complications. Perioperative all-cause mortality rates varied across operations and were higher in elderly than in younger patients (1.4% vs. 0.2%, P = 0.014) after abdominal surgery (2.4% vs. 0.1%, P = 0.006) and especially after abdominal aortic aneurysm repair (2.8% vs. 0%, P = 0.035). In the elderly cohort, the mortality rate was <1% for almost 60% of all operations. In logistic regression analysis, only preoperative hypertension (odds ratio [OR] = 72.5, 95% confidence interval [CI] 9.4-557.6), congestive heart failure (OR = 16.5, 95% CI 2.3-115.9), and perioperative cardiac (OR = 20.7, 95% CI 1.6-273.8) and pulmonary (OR = 41.7, 95% CI 7.9-218.9) complications were associated with a higher 30-day death risk. In this series, perioperative outcomes were not influenced by the type of elective surgical procedure. Though overall mortality after major vascular surgery was higher in patients > or 80 years old, age per se was not an independent factor of a higher perioperative mortality risk or fatal and nonfatal complications.
authors.affiliation: Department of Surgical and Gastroenterological Sciences, University of Padua, School of Medicine, Padua, Italy. enzo.ballotta@unipd.it
authors.forename: Enzo
authors.initials: E
authors.lastname: Ballotta
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Da Giau
authors.forename: Carmelo
authors.initials: C
authors.lastname: Militello
authors.forename: Oreste
authors.initials: O
authors.lastname: Terranova
authors.forename: Antonio
authors.initials: A
authors.lastname: Piccoli
mesh_terms: D000367:Age Factors; D000369:Aged, 80 and over; D000375:Aging; D017544:Aortic Aneurysm, Abdominal / Q000401:mortality / Q000601:surgery; D002318:Cardiovascular Diseases / Q000401:mortality / Q000601:surgery*; D017558:Elective Surgical Procedures / Q000009:adverse effects; D005260:Female; D006331:Heart Diseases / Q000209:etiology* / Q000401:mortality; D006333:Heart Failure / Q000150:complications / Q000401:mortality; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000401:mortality; D016015:Logistic Models; D008171:Lung Diseases / Q000209:etiology* / Q000401:mortality; D008297:Male; D016017:Odds Ratio; D012042:Registries; D012189:Retrospective Studies; D018570:Risk Assessment; D012307:Risk Factors; D013997:Time Factors; D016896:Treatment Outcome; D014656:Vascular Surgical Procedures / Q000009:adverse effects* / Q000401:mortality