title: Comparing neuropsychological function before and during haemodialysis: a habituating selective deficit for prose recall.
abstract: This study was based on the clinical observation that patients receiving haemodialysis(HD) showed poor retention for complex verbal information. To investigate this hypothesis, 45 patients with endstage renal disease were administered a neuropsychological (NP) test battery, including a test of prose recall on two occasions, 7 days apart (pre-dialysis and whilst dialysing). A range of demographic, biochemical and mood variables were also assessed. Results revealed a selective deficit for prose recall whilst dialysing compared to pre-dialysis performance, which habituated in the long-term. Possible physiological and psychological bases of these effects in HD patients are discussed.
authors.affiliation: Clinical Neuropsychology Department, National Hospital for Neurology and Neurosurgery, Queen's Square, London, UK. karen.oaksford@uclh.nhs.uk
authors.forename: Karen
authors.initials: K
authors.lastname: Oaksford
authors.forename: Mike
authors.initials: M
authors.lastname: Oaksford
authors.forename: Mohammad
authors.initials: M
authors.lastname: Ashraf
authors.forename: Gillian
authors.initials: G
authors.lastname: Fitzgibbon
mesh_terms: D000339:Affect; D003072:Cognition Disorders / Q000175:diagnosis / Q000453:epidemiology*; D005260:Female; D006185:Habituation, Psychophysiologic; D006801:Humans; D008091:Literature; D008297:Male; D011939:Mental Recall; D008875:Middle Aged; D009483:Neuropsychological Tests; D006435:Renal Dialysis / Q000706:statistics & numerical data*; D012720:Severity of Illness Index