Effectiveness of pneumococcal conjugate vaccine in Greater Vancouver, Canada: 2004-2005.
Active, population-based surveillance for invasive pneumococcal infections in Greater Vancouver (population 473,000 children) demonstrated a rapid, substantial decrease in incidence rates for children 6-23 months old with routine infant vaccination. In the subpopulation with best case ascertainment disease rates for 6-23 month olds decreased 84.6% (92.5% for vaccine serotypes).
Bjornson
Gordean
G
Vaccine Evaluation Center, BC Children's Hospital, Vancouver, B.C., Canada.
Scheifele
David W
DW
Bettinger
Julie
J
Patrick
David M
DM
Gustafson
Larry
L
Daly
Patricia
P
Tyrrell
Gregory J
GJ
D000293:Adolescent; D002170:Canada / Q000453:epidemiology; D002648:Child; D002675:Child, Preschool; D000069443:Heptavalent Pneumococcal Conjugate Vaccine; D006801:Humans; D015994:Incidence; D007223:Infant; D007231:Infant, Newborn; D022401:Meningococcal Vaccines / Q000276:immunology*; D011008:Pneumococcal Infections / Q000453:epidemiology* / Q000517:prevention & control*; D022242:Pneumococcal Vaccines / Q000276:immunology*
D000069443:Heptavalent Pneumococcal Conjugate Vaccine; D022401:Meningococcal Vaccines; D022242:Pneumococcal Vaccines