Daphlongeranines A and B, two novel alkaloids possessing unprecedented skeletons from Daphniphyllum longeracemosum.
Two novel alkaloids, daphlongeranines A (1) and B (2), with an unprecedented ring system, were isolated from the fruits of Daphniphyllum longeracemosum. Their unique structures and relative stereochemistries were established on the basis of spectroscopic and single-crystal diffraction analysis. The proposed biosynthetic pathway was also discussed. Compounds 1 and 2 showed weak inhibition on platelet aggregation.
Li
Chun-Shun
CS
State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, Yunnan, PRC.
Di
Ying-Tong
YT
He
Hong-Ping
HP
Gao
Suo
S
Wang
Yue-Hu
YH
Lu
Yang
Y
Zhong
Jia-Liang
JL
Hao
Xiao-Jiang
XJ
D000470:Alkaloids / Q000737:chemistry*; D008958:Models, Molecular; D015394:Molecular Structure; D031995:Saxifragaceae / Q000737:chemistry*
D000470:Alkaloids; C522225:daphlongeranine A; C522226:daphlongeranine B