[Thiazide induced acute pulmonary edema: report of one case].
Acute pulmonary edema caused by thiazides is uncommon and of difficult diagnosis. It is considered an idiosyncratic reaction and the physiopathology or cardiac function changes are not well known. We report a 60 year-old female with a thiazide induced acute pulmonary edema who was followed with serial measurements of type B n-terminal natriuretic peptide fraction as marker for cardiac dysfunction. There was a significant elevation of the peptide, not associated to evidences of ventricular dysfunction. Its normalization paralleled the resolution of the clinical picture.
Andresen
Max
M
Programa de Medicina Intensiva, Unidad de Tratamiento Intensivo Médico, Hospital Clínico, Pontificia Universidad Católica de Chile, Chile. andresen@med.puc.cl
González
Alejandro
A
Espino
Alberto
A
Mercado
Marcelo
M
Regueira
Tomas
T
Dougnac
Alberto
A
D000208:Acute Disease; D000959:Antihypertensive Agents / Q000009:adverse effects*; D015415:Biomarkers / Q000097:blood; D005260:Female; D006801:Humans; D006852:Hydrochlorothiazide / Q000009:adverse effects*; D008875:Middle Aged; D020097:Natriuretic Peptide, Brain / Q000097:blood; D011654:Pulmonary Edema / Q000097:blood / Q000139:chemically induced*
D000959:Antihypertensive Agents; D015415:Biomarkers; D006852:Hydrochlorothiazide; D020097:Natriuretic Peptide, Brain