New sesquiterpenes and calebin derivatives from Curcuma longa.
One novel sesquiterpene with new skeleton, (6S)-2-methyl-6-(4-hydroxyphenyl-3-methyl)-2-hepten-4-one (1), two new bisabolane sesquiterpenes, (6S)-2-methyl-6-(4-hydroxyphenyl)-2-hepten-4-one (2), (6S)-2-methyl-6-(4-formylphenyl)-2-hepten-4-one (3), and two calebin derivatives, 4''-(4'''-hydroxyphenyl-3'''-methoxy)-2''-oxo-3''-butenyl-3-(4'-hydroxyphenyl)-propenoate (4) and 4''-(4'''-hydroxyphenyl)-2''-oxo-3''-butenyl-3-(4'-hydroxyphenyl-3'-methoxy)-propenoate (5) were isolated along with five known bisabolane sesquiterpenes from Curcuma longa. 1-4 were new compounds and 5 was a new natural product. Their structures were established by spectral methods.
Zeng
YongChi
Y
Department of Natural Products Chemistry 81#, Shenyang Pharmaceutical University, Shenyang, PR China.
Qiu
Feng
F
Takahashi
Kyoko
K
Liang
JianMu
J
Qu
GeXia
G
Yao
XinSheng
X
D002934:Cinnamates; D030024:Curcuma / Q000737:chemistry*; D003474:Curcumin / Q000031:analogs & derivatives* / Q000737:chemistry / Q000302:isolation & purification; D009682:Magnetic Resonance Spectroscopy; D039821:Monoterpenes; D012717:Sesquiterpenes / Q000737:chemistry / Q000302:isolation & purification*; D021241:Spectrometry, Mass, Electrospray Ionization
D002934:Cinnamates; D039821:Monoterpenes; D012717:Sesquiterpenes; C448819:calebin-A; D003474:Curcumin