Unusual manifestation of histoplasmosis in connective tissue diseases.
This report describes the coexistence of three patients with rheumatic diseases (systemic lupus erythematosus, rheumatoid arthritis, and dermatomyositis) and infections because of Histoplasma capsulatum. Connective tissue diseases and histoplasmosis share several clinical findings. Therefore, histoplasmosis could be misdiagnosed as connective tissue disease or a flare of these diseases. Such cases highlight the importance of awareness of histoplasmosis in immunocompromised patients, particularly in those originating from endemic areas.
Ceccato
F
F
Rheumatology Section, Department of Internal Medicine, Hospital J.M. Cullen, Santa Fe, Argentina.
Gongora
V
V
Zunino
A
A
Roverano
S
S
Paira
S
S
D000328:Adult; D001327:Autoimmune Diseases / Q000188:drug therapy; D001691:Biological Therapy; D003240:Connective Tissue Diseases / Q000150:complications* / Q000175:diagnosis*; D005260:Female; D006658:Histoplasma / Q000378:metabolism; D006660:Histoplasmosis / Q000150:complications* / Q000175:diagnosis*; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008875:Middle Aged; D015434:Panniculitis / Q000378:metabolism; D012216:Rheumatic Diseases / Q000378:metabolism; D012306:Risk
D007166:Immunosuppressive Agents