title: [One-stage single balloon multiple expansions percutaneous kyphoplasty: report of 18 cases].
abstract: OBJECTIVE
  To observe the effect and safety of one-stage single balloon multiple expansions percutaneous kyphoplasty (PKP) in treatment of osteoporotic vertebral compressive fracture (OVCF) and spinal tumor.
  
  
  METHODS
  One-stage single balloon multiple expansions PKP was performed on 18 patients, 5 males and 13 females, aged 68.77 (44 - 80), with 45 vertebrae, including 11 case of OVCF (with 29 diseased vertebrae), 11 cases of multiple vertebral fracture (with 19 diseased vertebrae), 5 cases of multiple myeloma (with 12 diseased vertebrae), and 2 case of spinal metastatic tumor (with 4 diseased vertebrae), the vital signs were record during operation. Pain relief and functional recovery were evaluated with visual analogue pain scale (VAS) and Oswestry disability index (ODI) scaling, and restoration of vertebral height and Cobb angle were evaluated by X-ray examination. Follow-up was conducted by telephone survey or clinic consults for 12.3 months (6 - 18 months).
  
  
  RESULTS
  Operation was successfully performed on all patients with an operative time of 29.3 min (55 - 127 min) per vertebra. The average pressure of the balloon expansion was 165 Psi (87 - 210 Psi), and the average balloon expanded volume was 3.25 ml (1.5 - 4 ml). A balloon was expanded 2 approximately 5 times in one operation with the average of 2.94 expanded times. The bone cement volume injected was 3.95 ml (2 - 8.5 ml) per vertebra. Epidural cement leakage was seen in 1 vertebra in 1 case and paraspinal leakage was seen in two vertebrae in 1 case. The VAS and ODI scoring of these patients were both decreased significantly after operation. Both the anterior height and midline height of vertebrae were significantly improved. The pain relief and functional recovery were substantial and maintained to the last follow-up without any re-collapse or adjacent level fracture.
  
  
  CONCLUSIONS
  one-stage single balloon multiple expansions PKP is effective, economic and safe in treatment of multi-level OVCF and spinal tumor.
authors.affiliation: Department of Spine Surgery, First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, China.
authors.forename: Zhao-Min
authors.initials: ZM
authors.lastname: Zheng
authors.forename: Guan-Ming
authors.initials: GM
authors.lastname: Kuang
authors.forename: Zhi-Yong
authors.initials: ZY
authors.lastname: Dong
authors.forename: Fo-Bao
authors.initials: FB
authors.lastname: Li
authors.forename: You
authors.initials: Y
authors.lastname: Lü
authors.forename: Hui
authors.initials: H
authors.lastname: Chen
authors.forename: Hui
authors.initials: H
authors.lastname: Liu
authors.forename: Kui-Bo
authors.initials: KB
authors.lastname: Zhang
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001178:Arthroplasty / Q000379:methods*; D002404:Catheterization; D005260:Female; D006801:Humans; D007738:Kyphosis / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D016103:Spinal Fractures / Q000601:surgery; D016896:Treatment Outcome