title: Hypoplasminogenemia with ligneous periodontitis: a failed local therapeutic approach.
abstract: BACKGROUND
  Hypoplasminogenemia is a rare condition that is associated with ligneous conjunctivitis, a form of chronic conjunctivitis characterized by firm, fibrin-rich, pseudomembranous lesions on the tarsal conjunctivae and oral lesions. Pseudomembranes may develop on the gingivae, and there may be periodontal involvement.
  
  
  METHODS
  Several therapeutic approaches have been developed to treat such patients, but they have had limited effect. We used gingivectomies, topical heparin, and corticosteroids to treat periodontal lesions in an 18-year-old girl.
  
  
  RESULTS
  This approach had no benefit.
  
  
  CONCLUSIONS
  The question remains about how best to manage patients with hypoplasminogenemia.
authors.affiliation: Department of Periodontology, Faculty of Dentistry, Istanbul University, Istanbul, Turkey. idil_kurtulus@yahoo.com
authors.forename: Idil
authors.initials: I
authors.lastname: Kurtulus
authors.forename: Aslan
authors.initials: A
authors.lastname: Gokbuget
authors.forename: Ahmet
authors.initials: A
authors.lastname: Efeoglu
authors.forename: Serdar
authors.initials: S
authors.lastname: Cintan
authors.forename: Katrin
authors.initials: K
authors.lastname: Tefs
authors.forename: Volker
authors.initials: V
authors.lastname: Schuster
authors.forename: Crispian
authors.initials: C
authors.lastname: Scully
mesh_terms: D000293:Adolescent; D000305:Adrenal Cortex Hormones / Q000008:administration & dosage; D005260:Female; D005343:Fibrinolytic Agents / Q000008:administration & dosage; D005881:Gingiva / Q000473:pathology / Q000601:surgery; D019214:Gingival Overgrowth / Q000188:drug therapy / Q000601:surgery*; D005890:Gingivectomy / Q000379:methods*; D006402:Hematologic Diseases / Q000188:drug therapy / Q000235:genetics / Q000601:surgery*; D006493:Heparin / Q000008:administration & dosage; D006801:Humans; D010518:Periodontitis; D010958:Plasminogen / Q000172:deficiency*; D012008:Recurrence; D017211:Treatment Failure
chemical_list: D000305:Adrenal Cortex Hormones; D005343:Fibrinolytic Agents; D010958:Plasminogen; D006493:Heparin