title: Exploiting ligand conformation in selective inhibition of non-ribosomal peptide synthetase amino acid adenylation with designed macrocyclic small molecules.
authors.affiliation: Tri-Institutional Training Program in Chemical Biology, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, Box 422, New York, New York 10021, USA.
authors.forename: Justin S
authors.initials: JS
authors.lastname: Cisar
authors.forename: Julian A
authors.initials: JA
authors.lastname: Ferreras
authors.forename: Rajesh K
authors.initials: RK
authors.lastname: Soni
authors.forename: Luis E N
authors.initials: LE
authors.lastname: Quadri
authors.forename: Derek S
authors.initials: DS
authors.lastname: Tan
mesh_terms: D000596:Amino Acids / Q000737:chemistry* / Q000378:metabolism*; D008024:Ligands; D047028:Macrocyclic Compounds / Q000737:chemistry* / Q000378:metabolism*; D015394:Molecular Structure; D010453:Peptide Synthases / Q000037:antagonists & inhibitors* / Q000737:chemistry / Q000378:metabolism; D017434:Protein Structure, Tertiary
chemical_list: D000596:Amino Acids; D008024:Ligands; D047028:Macrocyclic Compounds; D010453:Peptide Synthases