title: High-altitude illness and muscle physiology.
abstract: High-altitude illness is a growing concern in sports medicine that affects persons shortly after they have climbed to a new high-altitude level to which their body is not acclimatized. With the increasing popularity of extreme sports, such as high-altitude mountaineering, skiing, and snowboarding, the incidence of complications arising from sports activities at high altitudes is increasing. High-altitude pulmonary edema and high-altitude cerebral edema are potentially fatal conditions. The study of high-altitude muscle physiology has broad ramifications in creating training programs for elite endurance athletes. A thorough understanding of the pathophysiology, presentation, treatment, and prevention of high-altitude illness is necessary for the treatment of these patients.
authors.affiliation: NYU Hospital for Joint Diseases, Department of Orthopaedic Surgery, New York, New York, USA.
authors.forename: Wayne M
authors.initials: WM
authors.lastname: Weil
authors.forename: Philip J
authors.initials: PJ
authors.lastname: Glassner
authors.forename: Joseph A
authors.initials: JA
authors.lastname: Bosco
mesh_terms: D000531:Altitude; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D001929:Brain Edema / Q000209:etiology / Q000503:physiopathology / Q000628:therapy; D002121:Calcium Channel Blockers / Q000627:therapeutic use; D003907:Dexamethasone / Q000627:therapeutic use; D006801:Humans; D009543:Nifedipine / Q000627:therapeutic use; D010100:Oxygen / Q000097:blood; D011654:Pulmonary Edema / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology / Q000628:therapy; D012307:Risk Factors
chemical_list: D000893:Anti-Inflammatory Agents; D002121:Calcium Channel Blockers; D003907:Dexamethasone; D009543:Nifedipine; D010100:Oxygen