Polymer carriers for drug delivery in tissue engineering.
Growing demand for tissues and organs for transplantation and the inability to meet this need using by autogeneic (from the host) or allogeneic (from the same species) sources has led to the rapid development of tissue engineering as an alternative. Tissue engineering aims to replace or facilitate the regrowth of damaged or diseased tissue by applying a combination of biomaterials, cells and bioactive molecules. This review focuses on synthetic polymers that have been used for tissue growth scaffold fabrication and their applications in both cell and extracellular matrix support and controlling the release of cell growth and differentiation supporting drugs.
Sokolsky-Papkov
Marina
M
Department of Medicinal Chemistry and Natural Products, School of Pharmacy, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel.
Agashi
Kapil
K
Olaye
Andrew
A
Shakesheff
Kevin
K
Domb
Abraham J
AJ
D004337:Drug Carriers / Q000737:chemistry* / Q000145:classification; D016503:Drug Delivery Systems / Q000379:methods*; D006801:Humans; D036341:Intercellular Signaling Peptides and Proteins / Q000008:administration & dosage*; D011108:Polymers / Q000737:chemistry* / Q000145:classification; D023822:Tissue Engineering / Q000379:methods* / Q000639:trends
D004337:Drug Carriers; D036341:Intercellular Signaling Peptides and Proteins; D011108:Polymers