title: Finite element model of stresses in the anterior lens capsule of the eye.
abstract: Continuum biomechanics continues to aid in the design of clinical procedures and biomedical devices. Such design requires detailed information on the biomechanical properties of the tissues of interest as well as appropriate methods of analysis. In this paper, we use a fully nonlinear, virtual work based finite element method to study the normal stress field in the anterior lens capsule of the porcine eye. The analysis shows that recently measured regional variations in material symmetry may combine with regional variations in membrane thickness to yield a nearly uniform and equibiaxial stress field in normalcy. These findings are discussed in terms of potential implications to the underlying mechanobiology and in particular, in terms of perturbations in stress that result from cataract surgery, the most commonly performed surgical procedure in North America.
authors.affiliation: Department of Biomedical Engineering, Texas A&M University, Texas, TX, USA.
authors.forename: G
authors.initials: G
authors.lastname: David
authors.forename: J D
authors.initials: JD
authors.lastname: Humphrey
mesh_terms: D016880:Anisotropy; D003198:Computer Simulation; D004548:Elasticity; D020342:Finite Element Analysis; D006801:Humans; D007903:Lens Capsule, Crystalline / Q000502:physiology*; D008954:Models, Biological; D013314:Stress, Mechanical