title: 6450 nm wavelength tissue ablation using a nanosecond laser based on difference frequency mixing and stimulated Raman scattering.
abstract: A four-stage laser system was developed, emitting at a wavelength of 6450 nm with a 3-5 ns pulse duration, < or = 2 mJ pulse energy, and 1/2 Hz pulse repetition rate. The laser system successfully ablated rat brain tissue, where both the collateral damage and the ablation rate compare favorably with that previously observed with a Mark-III Free-Electron Laser.
authors.affiliation: Free-Electron Laser Laboratory, Duke University, Durham, North Carolina 27708, USA. edwards@fel.duke.edu
authors.forename: G S
authors.initials: GS
authors.lastname: Edwards
authors.forename: R D
authors.initials: RD
authors.lastname: Pearlstein
authors.forename: M L
authors.initials: ML
authors.lastname: Copeland
authors.forename: M S
authors.initials: MS
authors.lastname: Hutson
authors.forename: K
authors.initials: K
authors.lastname: Latone
authors.forename: A
authors.initials: A
authors.lastname: Spiro
authors.forename: G
authors.initials: G
authors.lastname: Pasmanik
mesh_terms: D000818:Animals; D001921:Brain / Q000378:metabolism / Q000473:pathology; D004583:Electrons; D004867:Equipment Design; D007834:Lasers; D055095:Optics and Photonics; D009991:Oscillometry; D051381:Rats; D017207:Rats, Sprague-Dawley; D012542:Scattering, Radiation; D013059:Spectrum Analysis, Raman / Q000379:methods*; D013997:Time Factors