title: Prevalence of asymptomatic intracranial atherosclerosis in high-risk patients.
abstract: We used transcranial Doppler to screen 3,057 patients who had at least one vascular risk factor of hypertension, diabetes, or hyperlipidemia and found 385 (12.6%) had middle cerebral artery stenosis. Elderly, hypertension, diabetes, and hyperlipidemia were associated factors. The prevalence escalated quadratically with increasing number of associated factors: from 7.2% for one, to 29.6% for four associated factors. Asymptomatic middle cerebral artery stenosis is common in patients with vascular risk factors.
authors.affiliation: Department of Medicine & Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong. ks-wong@cuhk.edu.hk
authors.forename: K S
authors.initials: KS
authors.lastname: Wong
authors.forename: P W
authors.initials: PW
authors.lastname: Ng
authors.forename: A
authors.initials: A
authors.lastname: Tang
authors.forename: R
authors.initials: R
authors.lastname: Liu
authors.forename: V
authors.initials: V
authors.lastname: Yeung
authors.forename: B
authors.initials: B
authors.lastname: Tomlinson
mesh_terms: D017677:Age Distribution; D000368:Aged; D015897:Comorbidity; D003430:Cross-Sectional Studies; D048909:Diabetes Complications / Q000453:epidemiology* / Q000503:physiopathology; D005260:Female; D006723:Hong Kong / Q000453:epidemiology; D006801:Humans; D006949:Hyperlipidemias / Q000453:epidemiology / Q000503:physiopathology; D006973:Hypertension / Q000453:epidemiology* / Q000503:physiopathology; D002537:Intracranial Arteriosclerosis / Q000000981:diagnostic imaging / Q000453:epidemiology* / Q000503:physiopathology; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D020768:Middle Cerebral Artery / Q000000981:diagnostic imaging / Q000473:pathology* / Q000503:physiopathology; D015995:Prevalence; D012307:Risk Factors; D017678:Sex Distribution; D014463:Ultrasonography