The effectiveness of vitamin "E" in the treatment of oral mucositis in children receiving chemotherapy.
The aim of this study was to study the effect of vitamin "E" in the treatment of oral mucositis. 80 patients with oral mucositis were randomly distributed into 2 groups: group A, topically applied vitamin "E" and group B, vitamin "E" was given systemically. The 2 groups were evaluated for 5 days. Results showed that in group A grades of oral mucositis improved significantly, while in group B no significant improvement was noticed. It is concluded that topical application of 100 mg vitamin "E" twice daily is an effective measure for the treatment of chemotherapy-induced oral mucositis.
El-Housseiny
Azza A
AA
Pediatric and Community Dentistry Department, Faculty of Dentistry, University of Alexandria, El-Ibrahimia, Alexandria, Egypt. ahussini@hotmail.com
Saleh
Susan M
SM
El-Masry
Ashraf A
AA
Allam
Amany A
AA
D000284:Administration, Oral; D000287:Administration, Topical; D000970:Antineoplastic Agents / Q000009:adverse effects*; D000975:Antioxidants / Q000008:administration & dosage*; D002648:Child; D006801:Humans; D052016:Mucositis / Q000139:chemically induced / Q000188:drug therapy*; D013280:Stomatitis / Q000139:chemically induced / Q000188:drug therapy*; D014810:Vitamin E / Q000008:administration & dosage*; D014815:Vitamins / Q000008:administration & dosage*
D000970:Antineoplastic Agents; D000975:Antioxidants; D014815:Vitamins; D014810:Vitamin E