Capillary electrophoresis-high resolution sector field inductively coupled plasma mass spectrometry.
The background and applications of high resolution sector field inductively coupled plasma mass spectrometry (HR-ICP-MS) as a detector for capillary (CE) and gel electrophoretic separations are reviewed. Notable progress has been made in the fields of bioinorganic and environmental (geo-) chemistry. Metallomics, the study of metal species interactions and functions in biological systems, puts substantial technical demands on speciation analysis. The combination of high species resolving power (CE) and high sensitivity-high mass resolving power (HR-ICP-MS) provides a solid base to meet such demands.
Sonke
Jeroen E
JE
Laboratoire des Mécanismes et Transferts en Géologie, CNRS/IRD/Université Paul Sabatier Toulouse III, 14 avenue Edouard Bélin, 31400 Toulouse, France. sonke@lmtg.obs-mip.fr
Salters
Vincent J M
VJ
D003198:Computer Simulation; D019075:Electrophoresis, Capillary / Q000379:methods*; D007554:Isotopes / Q000032:analysis; D008668:Metallothionein / Q000032:analysis; D008670:Metals / Q000032:analysis; D010758:Phosphorus / Q000032:analysis; D012643:Selenium; D012680:Sensitivity and Specificity; D021241:Spectrometry, Mass, Electrospray Ionization / Q000295:instrumentation / Q000379:methods*; D013056:Spectrophotometry, Ultraviolet; D014131:Trace Elements / Q000032:analysis
D007554:Isotopes; D008670:Metals; D014131:Trace Elements; D010758:Phosphorus; D008668:Metallothionein; D012643:Selenium