title: [Wavefront aberrations and subjective quality of vision after wavefront-guided LASIK: first results].
abstract: OBJECTIVE
  To investigate the clinical impact of the postoperative ocular wavefront error (WFE) on subjective quality of vision (SQV) after LASIK.
  
  
  METHODS
  Forty-one myopic eyes of 21 patients underwent uneventful LASIK (median -4.63 D). Preoperatively and 1 month postoperatively, WFE measurements were performed and overall SQV was assessed for two lighting conditions (photopic and mesopic) with a questionnaire. Three different WFE representations were computed for a pupil diameter of 6 mm: (1) the visual quality metric VSOTF (visual Strehl ratio based on the optical transfer function), (2) RMS (root mean square) values of the Zernike orders 2-5, and (3) individual Zernike coefficient for orders 2-5. The impact of the postoperative WFE on SQV was calculated using linear regression analysis.
  
  
  RESULTS
  For photopic conditions R(2) was 0.24 for model 1 (VSOTF), 0.31 for model 2 (RMS values), and 0.29 for model 3 (Zernike coefficients). Second-and fifth-order aberrations had significant influence on SQV. For mesopic conditions, results were similar.
  
  
  CONCLUSIONS
  Subjective quality of vision after wavefront-guided LASIK could be explained partially by the ocular WFE.
authors.affiliation: Klinik für Augenheilkunde, Johann-Wolfgang-Goethe-Universität, Theodor-Stern-Kai 7, 60590, Frankfurt am Main, Deutschland.
authors.forename: J
authors.initials: J
authors.lastname: Bühren
authors.forename: A
authors.initials: A
authors.lastname: Strenger
authors.forename: T
authors.initials: T
authors.lastname: Martin
authors.forename: T
authors.initials: T
authors.lastname: Kohnen
mesh_terms: D005260:Female; D006801:Humans; D020731:Keratomileusis, Laser In Situ / Q000009:adverse effects* / Q000379:methods*; D008297:Male; D009216:Myopia / Q000150:complications / Q000175:diagnosis / Q000601:surgery; D010865:Pilot Projects; D012030:Refractive Errors / Q000175:diagnosis* / Q000209:etiology*; D014786:Vision Disorders / Q000175:diagnosis* / Q000209:etiology*; D014787:Vision Tests