title: Maturation of the auditory system: 1. Transient otoacoustic emissions as an index of inner ear maturation.
abstract: The transiently evoked otoacoustic emission amplitude of 42 preterm babies (84 ears; post-conceptional age [PCA] 30-36 weeks) was compared with the TEOAE amplitude of 39 full-term babies (78 ears; PCA 37-45 weeks) in order to trace the inner ear maturation characteristics. An ILO-92 otoacoustic emission recording system was used with linear clicks of 70 dB peak equivalent SPL. The results obtained indicated: (1) There was no statistically significant difference between preterm and full-term ears; (2) There was no significant difference between males and females; (3) There was a significant difference between left and right ear TEOAE amplitude; (4) The interaction of ear with age in relation to TEOAE amplitude was statistically significant; (5) Noise and stimulus parameters did not reveal any significant differences between right and left ears; (6) A positive correlation existed between birthweight and TEOAE amplitude; and (7) A negative correlation existed between aminoglycoside treatment and TEOAE amplitude. The results indicate subtle changes in TEOAE amplitude over time, showing a natural development of the inner ear function during the process of maturation.
authors.affiliation: 1st Department of Otorhinolaryngology, University of Athens, Hippokration Hospital of Athens, Greece. zoilen@hotmail.com
authors.forename: Eleni
authors.initials: E
authors.lastname: Gkoritsa
authors.forename: Stavros
authors.initials: S
authors.lastname: Korres
authors.forename: Ioannis
authors.initials: I
authors.lastname: Psarommatis
authors.forename: Michael
authors.initials: M
authors.lastname: Tsakanikos
authors.forename: Nikolaos
authors.initials: N
authors.lastname: Apostolopoulos
authors.forename: Eleftherios
authors.initials: E
authors.lastname: Ferekidis
mesh_terms: D000367:Age Factors; D007758:Ear, Inner / Q000254:growth & development* / Q000502:physiology; D005260:Female; D005865:Gestational Age; D006309:Hearing / Q000502:physiology*; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D008297:Male; D017084:Otoacoustic Emissions, Spontaneous / Q000502:physiology*