[HPCE determination of matrine in matrine liposome].
OBJECTIVE
To establish an HPCE method for the determination of matrine in Matrine Liposome.


METHODS
HPCE was used. The best condition was achieved with a fused silica capillary tube( 150 cm x 75 microm), 0.25 mol/L phosphate buffer (pH 6.8), at constant voltage of 20 kV and temperature at 25 degrees C. The UV detection wavelength was 206 nm.


RESULTS
The calibration curve was linear in the range of 0.3-6.025 mg/ml for matrine (0.9995). The average recovery of matrine was 97.3%.


CONCLUSIONS
This methods is simple, quick, accurate and suitable for the quality control for Matrine Liposome.
Zhang
Xiu-ming
XM
Central Station of Chinese Medicinal Materials Information, Station Food and Drug Administration, Guangzhou 510080, China.
Liu
Xiao-ping
XP
Li
Hui
H
D000470:Alkaloids / Q000032:analysis*; D004337:Drug Carriers; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification; D019075:Electrophoresis, Capillary / Q000379:methods*; D007887:Fabaceae / Q000737:chemistry; D006863:Hydrogen-Ion Concentration; D008081:Liposomes; D010946:Plants, Medicinal / Q000737:chemistry*; D011807:Quinolizines / Q000032:analysis*; D015203:Reproducibility of Results; D000093842:Matrines
D000470:Alkaloids; D004337:Drug Carriers; D004365:Drugs, Chinese Herbal; D008081:Liposomes; D011807:Quinolizines; D000093842:Matrines