Long-term support with milrinone prior to cardiac transplantation in a neonate with left ventricular noncompaction cardiomyopathy.
A 2-week-old female infant presented with acute decompensated left ventricular failure. Echocardiography diagnosed left ventricular noncompaction cardiomyopathy with dilated phenotype and a left ventricular shortening fraction <10%. The infant was mechanically ventilated for 2 weeks and then successfully extubated. She was maintained on intravenous milrinone for 6 months until she underwent successful orthotopic heart transplantation. Young children can be supported with inotropes for prolonged periods while awaiting heart transplantation.
McMahon
C J
CJ
Department of Paediatric Cardiology, Heart Failure Unit, Our Lady's Hospital for Sick Children, Crumlin, Dublin 12, Ireland. cmcmahon992004@yahoo.com
Murchan
H
H
Prendiville
T
T
Burch
M
M
D009202:Cardiomyopathies / Q000188:drug therapy* / Q000601:surgery; D002316:Cardiotonic Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D003131:Combined Modality Therapy; D005260:Female; D016027:Heart Transplantation; D006801:Humans; D007231:Infant, Newborn; D007262:Infusions, Intravenous; D020105:Milrinone / Q000008:administration & dosage / Q000627:therapeutic use*; D012121:Respiration, Artificial; D018487:Ventricular Dysfunction, Left / Q000188:drug therapy / Q000209:etiology
D002316:Cardiotonic Agents; D020105:Milrinone