title: [Seven kinds of new SCCmec type in Methicillin-resistant Staphyloccus aureus and their susceptibility to the antibiotics].
abstract: In order to explore the resistance and the staphylococcal chromosome cassette mec (SCCmec) types of Methicillin-resistant S. aureus (MRSA) in the area of Haikou, 686 strains of MRSA had been distinguished from 1174 strains of S. aureus using PBP2a testing. The resistance to the seven deputies of seven kinds antibiotics which in common use in clinic, including Oxacillin, Vancomycin, Doxycyclin, Amikacin, Erythromycin, Chloramphenicol, Ciprofloxacin, and SCCmec type of 58 strains had been tested using the K-B Agar diffuse, E-test and multiplex PCR strategy, and seven kinds of new SCCmec types were found in 17 strains. Their specialties of structure are: type-new3 possess four loci of A, F, H, M; New4 possess three loci of F, H, M; New5 possess three loci of D, B, M; New6 possess three loci of A, B, M; New7 possess four loci of H, E, C, M; New8 possess two loci of A, M; New9 possess three loci of A, C, M. All of them are different from the types reported. The strains carrying new SCC mec types are different from that carrying old SCC mec types in the epidemical distribution and resistance to the antibiotics: they were mostly isolated from the out-patients and have high level and wider range of resistance to antibiotics and deserve to pay more attention.
authors.affiliation: State Key Laboratory of Tropical Crop Biotechnology, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, China. hnnkoyfx@yahoo.com.cn
authors.forename: Fan-xian
authors.initials: FX
authors.lastname: Ouyang
authors.forename: Ping-feng
authors.initials: PF
authors.lastname: Bu
authors.forename: Hui-qin
authors.initials: HQ
authors.lastname: Huang
authors.forename: Shi-xiang
authors.initials: SX
authors.lastname: Bao
mesh_terms: D001426:Bacterial Proteins / Q000235:genetics*; D002876:Chromosomes, Bacterial; D024881:Drug Resistance, Bacterial; D055624:Methicillin-Resistant Staphylococcus aureus / Q000145:classification* / Q000187:drug effects / Q000235:genetics; D008826:Microbial Sensitivity Tests; D046915:Penicillin-Binding Proteins; D016133:Polymerase Chain Reaction
chemical_list: D001426:Bacterial Proteins; D046915:Penicillin-Binding Proteins; C487789:mecA protein, Staphylococcus aureus