Oxaaza cyclophanes in the recognition of nucleotides. The role of oxygen and electron-rich aromatic rings.
Dioxapolyaza cyclophanes derived from resorcinol and different polyamine chains have been studied in aqueous solution as abiotic receptors for nucleotides. The presence of the additional ethyleneoxy subunits is reflected in a higher basicity and in a significant increase in the log K values for the interaction with nucleotides relative to that of related polyazacyclophanes.
Burguete
M I
MI
Department of Inorganic and Organic Chemistry, UAMOA. University Jaume I/CSIC, Castellón, Spain.
García-España
E
E
López-Diago
L
L
Luis
S V
SV
Miravet
J
J
Sroczynski
D
D
D003198:Computer Simulation; D043844:Crown Ethers / Q000737:chemistry*; D004583:Electrons; D006841:Hydrocarbons, Aromatic / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D008958:Models, Molecular; D009711:Nucleotides / Q000737:chemistry*; D010100:Oxygen / Q000737:chemistry*; D011199:Potentiometry
D043844:Crown Ethers; D006841:Hydrocarbons, Aromatic; D009711:Nucleotides; D010100:Oxygen