Adiponectin and renal disease progression: another epidemiologic conundrum?
In an analysis based on the Mild to Moderate Kidney Disease (MMKD) study, adiponectin, a pleiotropic, insulin-sensitizing, anti-inflammatory and vasculo-protective cytokine, was directly related to renal disease progression. The precise definition of this apparently paradoxical association now requires that the research focus be moved from the study database to the experimental laboratory.
Zoccali
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Dialisi e Trapianto Renale Ospedali Riuniti, Epidemiologia Clinica e Fisiopatologia delle Malattie Renali e dell'Ipertensione Arteriosa, Reggio Calabria, Italy. carmine.zoccali@ibim.cnr.it
Mallamaci
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F
D052242:Adiponectin / Q000378:metabolism*; D018450:Disease Progression; D005260:Female; D006801:Humans; D007674:Kidney Diseases / Q000453:epidemiology* / Q000209:etiology*; D008297:Male
D052242:Adiponectin