title: Successfully treated acute lymphoblastic leukemia associated with craniopharyngioma.
abstract: The authors report a 2-year-old boy with acute lymphoblastic leukemia (ALL) associated with craniopharyngioma. To our knowledge, this is the first such report. Magnetic resonance imaging showed a suprasellar tumor, an apparent cystic lesion, whereas cerebral computed tomography confirmed that the tumor exhibited calcification. Without surgical intervention for the suprasellar tumor, we initiated chemotherapy for ALL. After 1 year of chemotherapy, complete remission was achieved, and partial resection and radiation therapy were performed on the suprasellar tumor. At 4 years after completing leukemia chemotherapy, the patient remains in complete ALL remission and has had no recurrence of craniopharyngioma.
authors.affiliation: Department of Pediatrics, Dokkyo Medical University, Tochigi, Japan. hidekuro@dokkyomed.ac.jp
authors.forename: Hidemitsu
authors.initials: H
authors.lastname: Kurosawa
authors.forename: Takayuki
authors.initials: T
authors.lastname: Matsunaga
authors.forename: Naoto
authors.initials: N
authors.lastname: Shimura
authors.forename: Daisuke
authors.initials: D
authors.lastname: Nakajima
authors.forename: Susumu
authors.initials: S
authors.lastname: Hagisawa
authors.forename: Keitaro
authors.initials: K
authors.lastname: Fukushima
authors.forename: Kenichi
authors.initials: K
authors.lastname: Sugita
authors.forename: Kim
authors.initials: K
authors.lastname: Phyo
authors.forename: Osamu
authors.initials: O
authors.lastname: Arisaka
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001491:Basophils / Q000473:pathology; D001854:Bone Marrow Cells / Q000473:pathology; D002675:Child, Preschool; D003397:Craniopharyngioma / Q000150:complications / Q000188:drug therapy*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D010911:Pituitary Neoplasms / Q000150:complications / Q000188:drug therapy*; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000188:drug therapy* / Q000473:pathology