title: Polymer carriers for drug delivery in tissue engineering.
abstract: Growing demand for tissues and organs for transplantation and the inability to meet this need using by autogeneic (from the host) or allogeneic (from the same species) sources has led to the rapid development of tissue engineering as an alternative. Tissue engineering aims to replace or facilitate the regrowth of damaged or diseased tissue by applying a combination of biomaterials, cells and bioactive molecules. This review focuses on synthetic polymers that have been used for tissue growth scaffold fabrication and their applications in both cell and extracellular matrix support and controlling the release of cell growth and differentiation supporting drugs.
authors.affiliation: Department of Medicinal Chemistry and Natural Products, School of Pharmacy, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel.
authors.forename: Marina
authors.initials: M
authors.lastname: Sokolsky-Papkov
authors.forename: Kapil
authors.initials: K
authors.lastname: Agashi
authors.forename: Andrew
authors.initials: A
authors.lastname: Olaye
authors.forename: Kevin
authors.initials: K
authors.lastname: Shakesheff
authors.forename: Abraham J
authors.initials: AJ
authors.lastname: Domb
mesh_terms: D004337:Drug Carriers / Q000737:chemistry* / Q000145:classification; D016503:Drug Delivery Systems / Q000379:methods*; D006801:Humans; D036341:Intercellular Signaling Peptides and Proteins / Q000008:administration & dosage*; D011108:Polymers / Q000737:chemistry* / Q000145:classification; D023822:Tissue Engineering / Q000379:methods* / Q000639:trends
chemical_list: D004337:Drug Carriers; D036341:Intercellular Signaling Peptides and Proteins; D011108:Polymers