title: Effects of individual components of multiple behavior changes: the PREMIER trial.
abstract: OBJECTIVE
  To assess contributions of individual lifestyle changes on systolic blood pressure (SBP) changes.
  
  
  METHODS
  We examined associations between lifestyle behavior changes and SBP after 6 and 18 months in 782 PREMIER trial participants.
  
  
  RESULTS
  In multivariate models omitting weight, predicted SBP reductions ranged from (1)/2 to 1(1)/2 mm Hg for reduced urinary sodium, improved fitness, and adherence to the DASH diet (except sodium at 18 months). With weight included, only fitness change additionally predicted SBP at 18 months.
  
  
  CONCLUSIONS
  Several lifestyle behavior changes are important for BP lowering, but are difficult to detect when weight is included in multivariate models.
authors.affiliation: National Heart, Lung, and Blood Institute, Bethesda, MD 20892-7936, USA. obarzane@nhlbi.nih.gov
authors.forename: Eva
authors.initials: E
authors.lastname: Obarzanek
authors.forename: William M
authors.initials: WM
authors.lastname: Vollmer
authors.forename: Pao-Hwa
authors.initials: PH
authors.lastname: Lin
authors.forename: Lawton S
authors.initials: LS
authors.lastname: Cooper
authors.forename: Deborah R
authors.initials: DR
authors.lastname: Young
authors.forename: Jamy D
authors.initials: JD
authors.lastname: Ard
authors.forename: Victor J
authors.initials: VJ
authors.lastname: Stevens
authors.forename: Denise G
authors.initials: DG
authors.lastname: Simons-Morton
authors.forename: Laura P
authors.initials: LP
authors.lastname: Svetkey
authors.forename: David W
authors.initials: DW
authors.lastname: Harsha
authors.forename: Patricia J
authors.initials: PJ
authors.lastname: Elmer
authors.forename: Lawrence J
authors.initials: LJ
authors.lastname: Appel
mesh_terms: D000328:Adult; D000428:Alcohol Drinking / Q000517:prevention & control; D001521:Behavior Therapy; D001794:Blood Pressure; D015992:Body Mass Index; D001835:Body Weight; D003131:Combined Modality Therapy; D018752:Diet, Fat-Restricted; D004039:Diet, Sodium-Restricted; D002149:Energy Intake; D015444:Exercise; D005260:Female; D005500:Follow-Up Studies; D015438:Health Behavior; D006339:Heart Rate; D006801:Humans; D006973:Hypertension / Q000628:therapy*; D008019:Life Style; D008297:Male; D015999:Multivariate Analysis; D010809:Physical Fitness; D012964:Sodium / Q000652:urine; D015431:Weight Loss
chemical_list: D012964:Sodium