title: In vitro evaluation of the effectiveness of acidic fluoride dentifrices.
abstract: This study evaluated the effectiveness of acidic low-fluoride dentifrices compared to conventional neutral dentifrices. Enamel blocks were submitted to pH cycling and treatment with slurries of dentifrices containing 0, 275, 412, 550 and 1,100 microg F/g (pH 4.5 or 7.0), and also a commercial dentifrice (1,100 microg F/g) and a commercial children's dentifrice (500 mug F/g). Variations in surface microhardness and in the mineral content in enamel after pH cycling were calculated. Enamel blocks treated with acidic dentifrices exhibited less mineral loss compared to neutral dentifrices (ANOVA; p < 0.05). The acidic dentifrices with 412 and 550 microg F/g had the same effectiveness as the neutral 1,100-microg F/g dentifrice and commercial 1,100-microg F/g dentifrice.
authors.affiliation: Araçatuba Dental School, UNESP-São Paulo State University, Araçatuba, SP, Brazil.
authors.forename: K M R P
authors.initials: KM
authors.lastname: Alves
authors.forename: J P
authors.initials: JP
authors.lastname: Pessan
authors.forename: F L
authors.initials: FL
authors.lastname: Brighenti
authors.forename: K S
authors.initials: KS
authors.lastname: Franco
authors.forename: F A L
authors.initials: FA
authors.lastname: Oliveira
authors.forename: M A R
authors.initials: MA
authors.lastname: Buzalaf
authors.forename: K T
authors.initials: KT
authors.lastname: Sassaki
authors.forename: A C B
authors.initials: AC
authors.lastname: Delbem
mesh_terms: D000818:Animals; D002118:Calcium / Q000032:analysis; D002327:Cariostatic Agents / Q000627:therapeutic use*; D002417:Cattle; D003743:Dental Enamel / Q000737:chemistry / Q000187:drug effects*; D003802:Dentifrices / Q000737:chemistry / Q000627:therapeutic use*; D004305:Dose-Response Relationship, Drug; D005459:Fluorides / Q000032:analysis / Q000627:therapeutic use*; D006244:Hardness / Q000187:drug effects; D006863:Hydrogen-Ion Concentration; D010758:Phosphorus / Q000032:analysis; D013499:Surface Properties / Q000187:drug effects
chemical_list: D002327:Cariostatic Agents; D003802:Dentifrices; D010758:Phosphorus; D005459:Fluorides; D002118:Calcium