title: Nematicidal activity of 5-hydroxymethyl-2-furoic acid against plant-parasitic nematodes.
abstract: A nematicide, 5-hydroxymethyl-2-furoic acid (1), was isolated from cultures of the fungus Aspergillus sp. and its structure was identified by spectroscopic analysis. Compound 1 showed effective nematicidal activities against the pine wood nematode Bursaphelenchus xylophilus and the free-living nematode Caenorhabditis elegans without inhibitory activity against plant growth, but 1 did not show any effective nematicidal activity against Pratylenchus penetrans.
authors.affiliation: Department of Biological and Environmental Chemistry, Faculty of Agriculture, Tottori University, Koyama, Tottori, Tottori 680-8553, Japan.
authors.forename: Yasuo
authors.initials: Y
authors.lastname: Kimura
authors.forename: Satoko
authors.initials: S
authors.lastname: Tani
authors.forename: Asami
authors.initials: A
authors.lastname: Hayashi
authors.forename: Kouhei
authors.initials: K
authors.lastname: Ohtani
authors.forename: Shozo
authors.initials: S
authors.lastname: Fujioka
authors.forename: Tsuyoshi
authors.initials: T
authors.lastname: Kawano
authors.forename: Atsumi
authors.initials: A
authors.lastname: Shimada
mesh_terms: D000818:Animals; D000969:Antinematodal Agents / Q000494:pharmacology*; D017173:Caenorhabditis elegans / Q000187:drug effects; D018552:Daucus carota / Q000254:growth & development; D005663:Furans / Q000737:chemistry / Q000494:pharmacology*; D018545:Lactuca / Q000254:growth & development; D009682:Magnetic Resonance Spectroscopy; D008958:Models, Molecular; D015394:Molecular Structure; D009348:Nematoda / Q000187:drug effects*; D028223:Pinus / Q000254:growth & development / Q000469:parasitology*; D010935:Plant Diseases / Q000469:parasitology; D031224:Raphanus / Q000254:growth & development; D036226:Seedlings / Q000254:growth & development; D014934:Wood / Q000469:parasitology
chemical_list: D000969:Antinematodal Agents; D005663:Furans