Reduction of bacterial adhesion on ion-implanted stainless steel surfaces.
The high incidence of infections caused by the use of biomedical devices has a severe impact on human health. An approach to reduce the complications is to modify the surface properties of biomedical devices. In this paper, stainless steel disks were implanted with N(+), O(+) and SiF(3)(+), respectively, by an ion implantation technique. The surface properties of the ion-implanted surfaces were characterized, including their surface chemical composition, roughness, topography, wettability and surface energy. Bacterial adhesion of Staphylococcus epidermidis and Staphylococcus aureus, which frequently cause medical device-associated infections was evaluated. The experimental results showed that these implanted stainless steels, particularly SiF(3)(+) implanted stainless steel performed much better than untreated stainless steel control on reducing bacterial attachment.
Zhao
Q
Q
Department of Mechanical Engineering, University of Dundee, Dundee, UK. q.zhao@dundee.ac.uk
Liu
Y
Y
Wang
C
C
Wang
S
S
Peng
N
N
Jeynes
C
C
D000327:Adsorption; D001422:Bacterial Adhesion / Q000187:drug effects*; D018441:Biofilms / Q000187:drug effects; D002412:Cations / Q000737:chemistry / Q000494:pharmacology*; D004203:Disinfection / Q000379:methods; D004586:Electrophoresis; D004869:Equipment Safety / Q000379:methods; D005459:Fluorides / Q000737:chemistry / Q000494:pharmacology; D006801:Humans; D009584:Nitrogen / Q000737:chemistry / Q000494:pharmacology; D010100:Oxygen / Q000737:chemistry / Q000494:pharmacology; D017655:Silicon Compounds / Q000737:chemistry / Q000494:pharmacology; D013193:Stainless Steel / Q000737:chemistry*; D013211:Staphylococcus aureus / Q000166:cytology / Q000187:drug effects; D013212:Staphylococcus epidermidis / Q000166:cytology / Q000187:drug effects; D013499:Surface Properties
D002412:Cations; D017655:Silicon Compounds; D013193:Stainless Steel; C054375:silicon fluoride; D009584:Nitrogen; D005459:Fluorides; D010100:Oxygen