title: Operative management of adult high-grade lumbosacral spondylolisthesis.
abstract: The surgical management of high-grade spondylolisthesis in adults remains challenging and controversial. Symptomatic patients often present with severe pain, neurologic deficits, or deformity. Although there are several surgical options, the decision to proceed with decompression and fusion depends on the patient's presenting symptoms and degree of instability. Posterolateral pedicle screw-rod fixation has improved rates of arthrodesis compared with traditional in situ fusions. Nevertheless, complications with operative management of high-grade spondylolisthesis can be severe.
authors.affiliation: Department of Neurological Surgery, University of California, San Francisco, San Francisco, CA 94143, USA. acostaf@neurosurg.ucsf.edu <acostaf@neurosurg.ucsf.edu>
authors.forename: Frank L
authors.initials: FL
authors.lastname: Acosta
authors.forename: Christopher P
authors.initials: CP
authors.lastname: Ames
authors.forename: Dean
authors.initials: D
authors.lastname: Chou
mesh_terms: D000328:Adult; D006801:Humans; D008159:Lumbar Vertebrae; D019635:Neurosurgical Procedures / Q000009:adverse effects*; D012307:Risk Factors; D012447:Sacrum; D013168:Spondylolisthesis / Q000145:classification / Q000601:surgery*