title: Clinical without histopathological manifestations of inflammation in a patient with primary intraorbital optic nerve sheath meningioma.
abstract: A 28-year-old man with a biopsy-proven benign intraorbital optic nerve sheath meningioma developed recurrent clinical manifestations of ipsilateral retrobulbar inflammation 9 years after undergoing postoperative radiation therapy. Debulking of the tumor 11 years after the original surgery again revealed no pathologic signs of inflammation. Whether growth of tumor, surgery, radiation, or edema triggered the inflammatory manifestations is unclear. Our case affirms that primary optic nerve meningiomas may rarely cause episodic manifestations resembling those of idiopathic orbital inflammation that resolve with corticosteroid treatment.
authors.affiliation: Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Boston, USA. simmons_lessell@meei.harvard.edu
authors.forename: Simmons
authors.initials: S
authors.lastname: Lessell
authors.forename: Jonathan W
authors.initials: JW
authors.lastname: Kim
authors.forename: Mark P
authors.initials: MP
authors.lastname: Hatton
authors.forename: Anat
authors.initials: A
authors.lastname: Stemmer-Rachamimov
authors.forename: Sureka
authors.initials: S
authors.lastname: Thiagalingham
authors.forename: Peter A D
authors.initials: PA
authors.lastname: Rubin
mesh_terms: D000328:Adult; D006801:Humans; D007249:Inflammation / Q000150:complications* / Q000473:pathology; D008137:Longitudinal Studies; D008297:Male; D008577:Meningeal Neoplasms / Q000150:complications* / Q000473:pathology / Q000601:surgery; D008579:Meningioma / Q000150:complications* / Q000473:pathology / Q000601:surgery; D019574:Optic Nerve Neoplasms / Q000150:complications* / Q000473:pathology / Q000601:surgery