Preparation of DL-2,3,4-trihydroxybutylarsonic acid and dl-2,3-dihydroxybutane-1,4-bis(arsonic acid): starting compounds for novel arsonolipids.
The reaction of DL-1,3-butadiene diepoxide and of DL-1,4-dibromo-2,3-butanediol with aqueous alkaline sodium arsenite, "Na(3)AsO(3)", gave mixtures of the title arsonic acids which can be separated by anion exchange resin. Characterization of by-products leads to a better understanding of these reactions. These compounds are valuable intermediates for the preparation of novel arsonic acids and bis(arsonic acids).
Tsivgoulis
Gerasimos M
GM
Department of Chemistry, University of Patras, Patras, Greece.
Lala
Maria A
MA
Ioannou
Panayiotis V
PV
D001152:Arsenicals / Q000138:chemical synthesis / Q000737:chemistry*; D018053:Arsenites / Q000737:chemistry; D002072:Butylene Glycols / Q000737:chemistry*; D007475:Ion Exchange Resins; D008055:Lipids / Q000737:chemistry*; D008956:Models, Chemical; D017670:Sodium Compounds / Q000737:chemistry; D013237:Stereoisomerism; D014867:Water / Q000737:chemistry
C523361:2,3,4-trihydroxybutylarsonic acid; C523362:2,3-dihydroxybutane-1,4-bis(arsonic acid); D001152:Arsenicals; D018053:Arsenites; D002072:Butylene Glycols; D007475:Ion Exchange Resins; D008055:Lipids; D017670:Sodium Compounds; D014867:Water; C017947:sodium arsenite