title: Early stages of development of the Taenia solium metacestode in pigs.
abstract: In order to identify the early stages of Taenia solium metacestodes, 12 pigs were each fed 100,000 viable eggs and later killed and necropsied at different times after infection. Hematoxylin-eosin (HE) and immunohistochemical techniques (IHCs) were used to identify onchospheres and cysticerci in different tissues. At 2 days postinfection (dpi) structures compatible with onchospheres were found in the lumen of the small intestine, and in the mesenteric blood vessels and lymph nodes. At 4 dpi, these same structures were observed in the small intestine, the liver, and skeletal muscles. Between 6 and 39 dpi, they were found only in skeletal muscles. Between 2 and 6 dpi the postonchospheres were circular and oval shaped and measured between 6 and 34 x 27 microm. From 14 to 39 dpi, well-developed metacestodes 550 x 750 microm were observed. IHCs support the identification of early stages of T. solium.
authors.affiliation: Department of Pathology, Faculty of Veterinary Medicine, National Autonomous University of Mexico, Circuito Exterior S/N, Ciudad Universitaria, Mexico, D.F.
authors.forename: Gerardo Salas
authors.initials: GS
authors.lastname: Garrido
authors.forename: Aline S
authors.initials: AS
authors.lastname: de Aluja
authors.forename: Fernando Constantino
authors.initials: FC
authors.lastname: Casas
mesh_terms: D000818:Animals; D005260:Female; D006801:Humans; D007421:Intestine, Small / Q000469:parasitology / Q000473:pathology; D008099:Liver / Q000469:parasitology / Q000473:pathology; D008198:Lymph Nodes / Q000469:parasitology / Q000473:pathology; D008297:Male; D008638:Mesenteric Arteries / Q000469:parasitology / Q000473:pathology; D008642:Mesenteric Veins / Q000469:parasitology / Q000473:pathology; D018482:Muscle, Skeletal / Q000469:parasitology / Q000473:pathology; D013552:Swine; D013553:Swine Diseases / Q000469:parasitology* / Q000473:pathology; D041201:Taenia solium / Q000254:growth & development*; D013622:Taeniasis / Q000469:parasitology / Q000473:pathology / Q000662:veterinary*