title: Extremely elevated serum CA-125 level as a result of unruptured unilateral endometrioma: the highest value reported.
abstract: OBJECTIVE
  To present a case of a unilateral endometrioma with extremely elevated serum CA-125 levels.
  
  
  METHODS
  Case report.
  
  
  METHODS
  University hospital.
  
  
  METHODS
  A 25-year-old woman with left adnexal mass and extremely elevated serum CA-125 level, 7,900 U/mL, underwent laparoscopy. There were unilateral endometrioma and stage IV endometriosis.
  
  
  METHODS
  Laparoscopic excision of the endometrioma, unilateral salpingectomy, adhesiolysis, ablation of endometriotic foci, and partial omentectomy were performed, and histopathologic results confirmed the diagnosis of endometriosis.
  
  
  METHODS
  Extremely elevated serum CA-125 levels and unruptured ovarian endometrioma.
  
  
  RESULTS
  On the second, sixth, and 13th days of the menstrual period, serum CA-125 levels were 7,900 U/mL, 1,577 U/mL, and 627 U/mL, respectively. On the third postoperative day serum CA-125 level was 56 U/mL.
  
  
  CONCLUSIONS
  Ovarian endometrioma and advanced endometriosis may be associated with extremely elevated serum CA-125 levels. For this reason ovarian endometrioma should be considered with respect to differential diagnosis of reproductive-age women presenting with an ovarian mass even if it resembles an ovarian malignancy.
authors.affiliation: Department of Obstetrics and Gynecology, Ankara University School of Medicine, Ankara, Turkey. korhankahraman@hotmail.com
authors.forename: Korhan
authors.initials: K
authors.lastname: Kahraman
authors.forename: Irem
authors.initials: I
authors.lastname: Ozguven
authors.forename: Mete
authors.initials: M
authors.lastname: Gungor
authors.forename: Cem Somer
authors.initials: CS
authors.lastname: Atabekoglu
mesh_terms: D000328:Adult; D018394:CA-125 Antigen / Q000097:blood*; D004715:Endometriosis / Q000097:blood* / Q000276:immunology / Q000473:pathology / Q000601:surgery; D005260:Female; D006801:Humans; D008598:Menstruation / Q000097:blood
chemical_list: D018394:CA-125 Antigen