title: Pseudoxanthoma elasticum with cerebrovascular accident.
abstract: A 65-year-old male presented with right hemiparesis and skin lesions. On examination, the patient had multiple, discrete, skin-colored papules on the neck and upper chest with wrinkling of the skin. The lateral part of the trunk and medial aspect of both upper arms showed atrophic plaques. A computerized tomography scan of the head showed dilatation of the basilar artery with a frontoparietal infarct. Funduscopic examination showed characteristic angioid streaks. Skin biopsy of the papule and atrophic plaques showed epidermal atrophy, calcium deposits in the mid-dermis and basophilic clumped and fragmented elastic fibers in the mid- and lower dermis, all findings consistent with pseudoxanthoma elasticum. We are reporting here a case of pseudoxanthoma elasticum with cerebrovascular accident.
authors.affiliation: Department of Pathology, Medical College Hospital, Trivandrum, Kerala, India. drnandakumar_g@yahoo.co.in
authors.forename: G Nanda
authors.initials: GN
authors.lastname: Kumar
authors.forename: K V
authors.initials: KV
authors.lastname: Ragi
authors.forename: Pradeep S
authors.initials: PS
authors.lastname: Nair
mesh_terms: D000368:Aged; D006801:Humans; D008297:Male; D011561:Pseudoxanthoma Elasticum / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D020521:Stroke / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy