Ortho-azo substituted phenylboronic acids for colorimetric sugar sensors.
The phenylboronic acids substituted with an azo group on the ortho-position show a significant change in UV-vis spectra upon sugar binding. A new mechanism for the spectral change of the dyes is proposed based on the formation and cleavage of B-N dative bond between boronic acid group and azo group.
Egawa
Yuya
Y
Graduate School of Pharmaceutical Sciences, Tohoku University, Aramaki, Aoba-ku, Sendai 980-8578, Japan. egawa@neutron.pharm.thoku.ac.jp <egawa@neutron.pharm.thoku.ac.jp>
Gotoh
Ryota
R
Niina
Satoshi
S
Anzai
Jun-ichi
J
D001895:Boron / Q000737:chemistry; D001897:Boronic Acids / Q000737:chemistry*; D002241:Carbohydrates / Q000737:chemistry*; D002626:Chemistry, Pharmaceutical / Q000379:methods*; D003124:Colorimetry / Q000379:methods*; D004396:Coloring Agents / Q000737:chemistry / Q000494:pharmacology*; D015195:Drug Design; D006863:Hydrogen-Ion Concentration; D007700:Kinetics; D009682:Magnetic Resonance Spectroscopy; D000432:Methanol / Q000737:chemistry; D008956:Models, Chemical; D015394:Molecular Structure; D009584:Nitrogen / Q000737:chemistry; D013056:Spectrophotometry, Ultraviolet / Q000295:instrumentation
D001897:Boronic Acids; D002241:Carbohydrates; D004396:Coloring Agents; C010686:benzeneboronic acid; D009584:Nitrogen; D001895:Boron; D000432:Methanol