title: Focal myometrial defect and partial placenta accreta in a pregnancy following bilateral uterine artery embolization.
abstract: A 29-year-old nulliparous patient was treated with uterine artery embolization (UAE) for a large symptomatic uterine fibroid, resulting in a marked reduction of the tumor volume. She subsequently conceived and progressed through pregnancy uneventfully. At cesarean section for breech presentation at term, a large fundal myometrial defect was encountered. In addition, the patient presented with unexpected partial placenta accreta, which resulted in massive atonic uterine bleeding. It is suggested that UAE was implicated in the pathogenesis of myometrial damage and abnormal placentation. It is proposed that the antenatal care of pregnancies after UAE include careful imaging of the placenta, its vasculature, and the thickness of overlying uterine wall so peripartum management can be appropriately planned.
authors.affiliation: Department of Obstetrics and Gynecology, Tayside University Hospitals, Perth PH1 1NX, UK. elmiligy@btinternet.com
authors.forename: Magdy
authors.initials: M
authors.lastname: El-Miligy
authors.forename: Adam
authors.initials: A
authors.lastname: Gordon
authors.forename: Graeme
authors.initials: G
authors.lastname: Houston
mesh_terms: D000328:Adult; D001158:Arteries; D001946:Breech Presentation; D002585:Cesarean Section; D004621:Embolization, Therapeutic / Q000009:adverse effects*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007889:Leiomyoma / Q000098:blood supply / Q000473:pathology / Q000628:therapy*; D050498:Live Birth; D008279:Magnetic Resonance Imaging; D008297:Male; D009215:Myometrium / Q000293:injuries*; D010921:Placenta Accreta / Q000209:etiology*; D006473:Postpartum Hemorrhage / Q000209:etiology; D011247:Pregnancy; D014594:Uterine Neoplasms / Q000098:blood supply / Q000473:pathology / Q000628:therapy*; D014599:Uterus / Q000098:blood supply* / Q000473:pathology; D014947:Wounds and Injuries / Q000209:etiology*