title: [Prevalence of vitamin D deficiency, insufficiency and secondary hyperparathyroidism in the elderly inpatients and living in the community of the city of São Paulo, Brazil].
abstract: The occurrence of osteoporotic fractures in the elderly is associated with reduced levels of vitamin D and resulting secondary hyperparathyroidism, and inpatients are the ones at a higher risk. In Brazil, given its high level of insolation, the populations large amount of vitamin D is inferred to be adequate. In this study we aimed to assess the serum levels of 25-hydroxivitamin D (25OHD), parathormone (PTH) and ionized calcium (Cai), as well as to analyze the prevalence of both hypovitaminosis D and secondary hyperparathyroidism in the elderly living in the city of São Paulo. We studied 177 inpatients (125 women and 52 men) with mean age (SD) 76.6 (9.0) years, and 243 outpatients (168 women and 75 men) aged 79.1 (5.9) years. In this assessment 71.2% in the inpatients group and 43.8% in the outpatients group had 25OHD levels below the minimum recommended (50 nmol/l), with the women presenting with levels considerably lower than the men. Secondary hyperparathyroidism occurred in 61.7% of the inpatients and in 54% of the outpatients. Considering the results achieved, we recommend vitamin D supplementation in effective doses for the Brazilian elderly population, in addition to suggesting a discussion for the implementation of vitamin D-enhanced food policies, particularly oriented to the ones at a greater risk.
authors.affiliation: Departamento de Endocrinologia, Escola Paulista de Medicina, Universidade Federal de São Paulo. gabrielasaraiva@uol.com.br
authors.forename: Gabriela Luporini
authors.initials: GL
authors.lastname: Saraiva
authors.forename: Maysa Seabra
authors.initials: MS
authors.lastname: Cendoroglo
authors.forename: Luiz Roberto
authors.initials: LR
authors.lastname: Ramos
authors.forename: Lara Miguel Quirino
authors.initials: LM
authors.lastname: Araújo
authors.forename: José Gilberto H
authors.initials: JG
authors.lastname: Vieira
authors.forename: Sérgio Setsuo
authors.initials: SS
authors.lastname: Maeda
authors.forename: Victória Z C
authors.initials: VZ
authors.lastname: Borba
authors.forename: Ilda
authors.initials: I
authors.lastname: Kunii
authors.forename: Lillian F
authors.initials: LF
authors.lastname: Hayashi
authors.forename: Marise
authors.initials: M
authors.lastname: Lazaretti-Castro
mesh_terms: D000328:Adult; D000368:Aged; D015415:Biomarkers / Q000097:blood; D001938:Brazil / Q000453:epidemiology; D002118:Calcium / Q000097:blood; D016022:Case-Control Studies; D005260:Female; D006707:Homes for the Aged / Q000706:statistics & numerical data; D006801:Humans; D006887:Hydroxycholecalciferols / Q000097:blood; D006962:Hyperparathyroidism, Secondary / Q000453:epidemiology* / Q000209:etiology; D007326:Institutionalization; D008297:Male; D010281:Parathyroid Hormone / Q000097:blood; D015995:Prevalence; D012737:Sex Factors; D014807:Vitamin D / Q000097:blood*; D014808:Vitamin D Deficiency / Q000097:blood / Q000150:complications / Q000453:epidemiology*
chemical_list: D015415:Biomarkers; D006887:Hydroxycholecalciferols; D010281:Parathyroid Hormone; D014807:Vitamin D; D002118:Calcium