title: Hirsutism and hyperandrogenism associated with hyperreactio luteinalis in a singleton pregnancy: a case report.
abstract: The incidence of hyperandrogenism during pregnancy is low, although the incidence of some of the ovarian diseases that can cause it is higher. Hyperreactio luteinalis is a rare benign condition that may mimic ovarian and trophoblastic malignancies. A 23-year-old woman at 20 weeks' gestational age presenting with severe hirsutism and ovarian masses was treated conservatively and subsequently gave birth to a healthy female neonate. Final diagnosis was hyperreactio luteinalis. Conservative management with close monitoring of patients with hyperreactio luteinalis represents the best approach in such rare cases. Counseling should be provided to reassure the patient as to the transient effects of hyperandrogenism on the mother and the fetus.
authors.affiliation: Division of Gynecology, Obstetrics and Pathophysiology of Human Reproduction, Department of Surgery, Maternal-Fetal Medicine, and Imaging, University of Cagliari, Cagliari, Italy. sangioni@yahoo.it
authors.forename: Stefano
authors.initials: S
authors.lastname: Angioni
authors.forename: Elaine
authors.initials: E
authors.lastname: Portoghese
authors.forename: Francesca
authors.initials: F
authors.lastname: Milano
authors.forename: Gian Benedetto
authors.initials: GB
authors.lastname: Melis
authors.forename: Anna Maria
authors.initials: AM
authors.lastname: Fulghesu
mesh_terms: D000328:Adult; D005260:Female; D006628:Hirsutism / Q000209:etiology*; D006801:Humans; D017588:Hyperandrogenism / Q000209:etiology*; D010049:Ovarian Diseases / Q000150:complications* / Q000473:pathology; D010053:Ovary / Q000473:pathology; D011247:Pregnancy; D011248:Pregnancy Complications / Q000473:pathology