title: Use of topical corticosteroids on chronic leg ulcers.
abstract: OBJECTIVE
  Topical corticosteroids are widely used in the management of chronic wounds, yet there is little evidence to support this. This pilot study aimed to identify current practice by three specialist nurses and to assess the efficacy of topical corticosteroids.
  
  
  METHODS
  Data on healing, pain relief, exudate reduction and control of hypergranulation tissue were collected on 34 patients whose wounds were treated with topical corticosteroids prospectively in three centres over a three-month period.
  
  
  RESULTS
  Twenty-seven patients (79%) benefited from the application of topical corticosteroid either in terms of healing, pain relief, exudate reduction or the control of hypergranulation tissue. Two wounds deteriorated and treatment was immediately withdrawn.
  
  
  CONCLUSIONS
  Suppression of inflammation plays an important role in healing and pain relief. Applying topical corticosteroids to the wound can accelerate healing and reduce pain in certain cases. However, careful monitoring is essential as there is a risk of sensitisation with prolonged use as well as a potential increased risk of infection.
authors.affiliation: Leg Ulcer Clinic, Department of Dermatology, Churchill Hospital, Oxford, UK. deborah.hofman@orh.nhs.uk
authors.forename: D
authors.initials: D
authors.lastname: Hofman
authors.forename: K
authors.initials: K
authors.lastname: Moore
authors.forename: R
authors.initials: R
authors.lastname: Cooper
authors.forename: M
authors.initials: M
authors.lastname: Eagle
authors.forename: S
authors.initials: S
authors.lastname: Cooper
mesh_terms: D000287:Administration, Topical; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002908:Chronic Disease; D005260:Female; D005938:Glucocorticoids / Q000008:administration & dosage*; D006801:Humans; D007871:Leg Ulcer / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D010865:Pilot Projects; D011446:Prospective Studies; D014647:Varicose Ulcer / Q000188:drug therapy; D014945:Wound Healing / Q000187:drug effects
chemical_list: D005938:Glucocorticoids