title: Calcium intake and the outcome of short-term weight management.
abstract: Experimental and epidemiological studies suggest that calcium intake is inversely related to weight gain. Calcium of dairy origin has been shown to be more effective in promoting weight loss. However, clinical studies yielded controversial results concerning the role of calcium intake in weight change. The aim of this study was to ascertain whether the addition of calcium can affect the outcome of 3-week weight management (WM) with a hypocaloric diet characterized by a decreased calcium intake. Overweight/ obese women (n=67; BMI 32.2+/-4.1 kg/m(2); age 49.1+/-12.1 years) underwent a 4-week comprehensive WM program. WM included a 7 MJ/day diet resulting in a stable weight during the first week and a 4.5 MJ/day diet with mean daily calcium intake 350 mg during the second to fourth week. Participants were divided into three age- and BMI-matched groups who received placebo or calcium (500 mg/day). Calcium was administered either as carbonate or calcium of dairy origin (Lactoval). There was no significant difference in weight loss in response to WM between the placebo-treated and calcium-treated groups. However, addition of calcium to the diet resulted in a lower hunger score in the Eating Inventory as well as a decrease in plasma resistin levels. Body composition measured by bioimpedance demonstrated that added calcium leads to preservation of fat-free mass. Nevertheless, a greater loss of fat-free mass in the placebo group might be partly due to a greater loss of water.
authors.affiliation: Institute of Endocrinology, Obesity Management Centre, Prague, Czech Republic.
authors.forename: K
authors.initials: K
authors.lastname: Kabrnová-Hlavatá
authors.forename: V
authors.initials: V
authors.lastname: Hainer
authors.forename: M
authors.initials: M
authors.lastname: Gojová
authors.forename: P
authors.initials: P
authors.lastname: Hlavatý
authors.forename: V
authors.initials: V
authors.lastname: Kopský
authors.forename: J
authors.initials: J
authors.lastname: Nedvídková
authors.forename: M
authors.initials: M
authors.lastname: Kunešová
authors.forename: J
authors.initials: J
authors.lastname: Pařízková
authors.forename: M
authors.initials: M
authors.lastname: Wagenknecht
authors.forename: M
authors.initials: M
authors.lastname: Hill
authors.forename: J
authors.initials: J
authors.lastname: Drbohlav
mesh_terms: D000328:Adult; D000704:Analysis of Variance; D002136:Calcium, Dietary / Q000008:administration & dosage*; D004038:Diet, Reducing; D019587:Dietary Supplements; D005260:Female; D006801:Humans; D006815:Hunger / Q000187:drug effects; D016555:Matched-Pair Analysis; D008875:Middle Aged; D009765:Obesity / Q000188:drug therapy*; D018709:Statistics, Nonparametric; D013997:Time Factors; D016896:Treatment Outcome; D015431:Weight Loss / Q000187:drug effects / Q000502:physiology*
chemical_list: D002136:Calcium, Dietary