title: Review on uraemic solutes II--variability in reported concentrations: causes and consequences.
abstract: The aim of this manuscript is to initiate a constructive discussion about deviations in measured concentrations of uraemic solutes; these deviations, if not perceived or handled appropriately, may lead to incorrect interpretations of the pathophysiological role of uraemic solutes and/or to erroneous therapeutic decisions. To come to an objective approach towards this problem, variability analysis of reported concentrations may be of help. Striking outliers should either be discarded or considered together with other values which are more consistent with the majority of reported data.
authors.forename: Raymond
authors.initials: R
authors.lastname: Vanholder
authors.forename: Nathalie
authors.initials: N
authors.lastname: Meert
authors.forename: Eva
authors.initials: E
authors.lastname: Schepers
authors.forename: Griet
authors.initials: G
authors.lastname: Glorieux
authors.forename: Angel
authors.initials: A
authors.lastname: Argiles
authors.forename: Philippe
authors.initials: P
authors.lastname: Brunet
authors.forename: Gerald
authors.initials: G
authors.lastname: Cohen
authors.forename: Tilman
authors.initials: T
authors.lastname: Drüeke
authors.forename: Harald
authors.initials: H
authors.lastname: Mischak
authors.forename: Goce
authors.initials: G
authors.lastname: Spasovski
authors.forename: Ziad
authors.initials: Z
authors.lastname: Massy
authors.forename: Joachim
authors.initials: J
authors.lastname: Jankowski
mesh_terms: D006801:Humans; D007676:Kidney Failure, Chronic / Q000503:physiopathology*; D014118:Toxins, Biological / Q000378:metabolism*; D014511:Uremia / Q000209:etiology / Q000503:physiopathology*
chemical_list: D014118:Toxins, Biological