title: Ineffectiveness of oral iron hydroxide polymaltose in iron-deficiency anemia.
abstract: Two hundred and forty one patients with iron deficiency anemia (IDA) were identified in a single institution over a 24-year period; of these, 75 individuals were studied as the result of persistent IDA despite the administration of oral iron hydroxide polymatose (IP). The levels of hemoglobin when the patients were referred for study after being given oral IP had a median of 10.3 g/dl; after administration of oral iron fumarate during periods ranging from 1 to 14 months, the levels of hemoglobin rose to a median of 12.5 g/dl (p>0.01). Our data support previous observations made in other countries about the ineffectiveness of oral IP in the treatment of individuals with IDA and should alert the clinician to avoid unnecessary consultations and misdiagnosis.
authors.affiliation: Centro de Hematología y Medicina Interna de Puebla, Puebla, PUE, Mexico. gruiz1@clinicaruiz.com
authors.forename: Guillermo J
authors.initials: GJ
authors.lastname: Ruiz-Argüelles
authors.forename: Angeles
authors.initials: A
authors.lastname: Díaz-Hernández
authors.forename: Carlos
authors.initials: C
authors.lastname: Manzano
authors.forename: Guillermo J
authors.initials: GJ
authors.lastname: Ruiz-Delgado
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D018798:Anemia, Iron-Deficiency / Q000188:drug therapy*; D002648:Child; D002675:Child, Preschool; D004341:Drug Evaluation; D005260:Female; D005290:Ferric Compounds / Q000008:administration & dosage / Q000627:therapeutic use*; D006454:Hemoglobins / Q000032:analysis; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D017211:Treatment Failure
chemical_list: D005290:Ferric Compounds; D006454:Hemoglobins; C013276:teferrol