title: Sequential treatment of depression in primary care.
abstract: BACKGROUND
  In the past decade, in clinical psychiatry several investigations suggested the usefulness of a sequential way of integrating pharmacotherapy and psychotherapy in mood disorders. The aim of this paper was to illustrate the practical implications of sequential treatment strategy for depression in primary care, with particular reference to the increasingly common problem of recurrent depression.
  
  
  METHODS
  The Authors tried to integrate the evidence which derives from meta-analyses and comprehensive general reviews with the insights which derive from controlled studies concerned with specific populations.
  
  
  CONCLUSIONS
  The sequential treatment of mood disorders is an intensive, two-stage approach, which derives from the awareness that one course of treatment with a specific tool (whether pharmacotherapy or psychotherapy) is unlikely to entail solution to the affective disturbances of patients, both in research and in clinical practice settings. The aim of the sequential approach is to add therapeutic ingredients as long as they are needed. In this sense, it introduces a conceptual shift in clinical practice.
authors.affiliation: Department of Psychology, University of Bologna, Bologna, Italy. chiara.rafanelli@unibo.it
authors.forename: C
authors.initials: C
authors.lastname: Rafanelli
authors.forename: G A
authors.initials: GA
authors.lastname: Fava
authors.forename: N
authors.initials: N
authors.lastname: Sonino
mesh_terms: D000928:Antidepressive Agents / Q000627:therapeutic use*; D015928:Cognitive Behavioral Therapy / Q000379:methods*; D003131:Combined Modality Therapy; D003865:Major Depressive Disorder / Q000209:etiology / Q000628:therapy*; D005194:Family Practice; D005260:Female; D006801:Humans; D008019:Life Style; D008297:Male; D012307:Risk Factors; D055502:Secondary Prevention; D016896:Treatment Outcome
chemical_list: D000928:Antidepressive Agents