eFSH in clinical equine practice.
Equine follicle stimulating hormone (eFSH) has been used to induce follicular development in transitional mares and problem acyclic mares, as well as superovulate cycling mares. The most efficacious protocol is to administer 12.5 mg eFSH, intramuscularly, twice daily beginning 5 to 7 days after ovulation when the diameter of the largest follicle is 20 to 25 mm. Prostaglandins are to be administered on the second day of eFSH therapy. Treatment with eFSH is continued for 3 to 5 days until follicle(s) are >or=35 mm in diameter. The mare is subsequently allowed to 'coast' for 36 h, after which human chorionic gonadotropin is administered to induce ovulation.
McCue
P M
PM
Colorado State University, Ft. Collins, CO 80523, and Rood and Riddle Equine Hospital, Lexington, KY 40580, United States. pmccue@colostate.edu
LeBlanc
M M
MM
Squires
E L
EL
D000818:Animals; D006063:Chorionic Gonadotropin / Q000494:pharmacology; D005260:Female; D005640:Follicle Stimulating Hormone / Q000494:pharmacology*; D006064:Gonadotropins, Equine / Q000494:pharmacology* / Q000627:therapeutic use; D006734:Horse Diseases / Q000188:drug therapy; D006736:Horses / Q000502:physiology*; D006801:Humans; D007247:Infertility, Female / Q000188:drug therapy / Q000662:veterinary; D006080:Ovarian Follicle / Q000166:cytology / Q000187:drug effects; D010062:Ovulation Induction / Q000662:veterinary*; D027724:Reproductive Techniques, Assisted / Q000662:veterinary; D013480:Superovulation / Q000187:drug effects
D006063:Chorionic Gonadotropin; D006064:Gonadotropins, Equine; D005640:Follicle Stimulating Hormone