title: Two new sesquiterpenes from Alisma orientalis.
abstract: Two new sesquiterpenoids named alismorientols A (1) and B (2) were isolated from the rhizomes of Alisma orientalis collected in Sichuan province, People's Republic of China. Their structures were elucidated based on spectroscopic analyses (1D and 2D NMR data including HSQC, HMBC, COSY, and ROESY) and X-ray crystallographic analysis. Anti-hepatitis B virus (HBV) bioassay revealed that compound 1 showed moderate anti-HBV activity in vitro with IC50 for HBsAg: 1.1 microM, for HBeAg: 14.7 microM.
authors.affiliation: State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Yunnan, PR China.
authors.forename: Zhi-Yong
authors.initials: ZY
authors.lastname: Jiang
authors.forename: Xue-Mei
authors.initials: XM
authors.lastname: Zhang
authors.forename: Jun
authors.initials: J
authors.lastname: Zhou
authors.forename: Feng-Xue
authors.initials: FX
authors.lastname: Zhang
authors.forename: Ji-Jun
authors.initials: JJ
authors.lastname: Chen
authors.forename: Yang
authors.initials: Y
authors.lastname: Lü
authors.forename: Li
authors.initials: L
authors.lastname: Wu
authors.forename: Qi-Tai
authors.initials: QT
authors.lastname: Zheng
mesh_terms: D034902:Alisma / Q000737:chemistry*; D018360:Crystallography, X-Ray; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D012717:Sesquiterpenes / Q000737:chemistry / Q000302:isolation & purification*; D013055:Spectrophotometry, Infrared
chemical_list: D012717:Sesquiterpenes