Considering an infectious etiology of sarcoidosis.
Sarcoidosis is a systemic granulomatous disease of unknown cause. An infectious etiology of sarcoidosis has long been suspected, but only recently has scientific evidence provided a strong link between infectious agents and sarcoidosis. Moreover, recent advances in our understanding of the relationships between sarcoidosis phenotype and host genetic factors may further illuminate the mechanisms linking infection and sarcoidosis.
Ezzie
Michael E
ME
Division of Pulmonary, Critical Care, and Sleep Medicine, The Ohio State University Medical Center, Columbus, OH 43210-1252, USA.
Crouser
Elliott D
ED
D001419:Bacteria / Q000145:classification; D001424:Bacterial Infections / Q000150:complications; D006105:Granulomatous Disease, Chronic / Q000235:genetics; D006801:Humans; D007239:Infections / Q000150:complications*; D007249:Inflammation / Q000503:physiopathology; D010641:Phenotype; D012507:Sarcoidosis / Q000209:etiology* / Q000235:genetics