Conjunctival involvement in Churg-Strauss syndrome.
OBJECTIVE
To describe an unusual case of Churg-Strauss syndrome (CSS) that presented with a conjunctival nodule and was successfully treated with oral corticosteroids.


METHODS
Case report.


RESULTS
A 30-year-old woman with a history of adult-onset asthma, seasonal allergies, and a lung mass presented with a nodular elevation of the conjunctiva. Excisional biopsy demonstrated necrotizing eosinophilic granulomas. Systemic evaluation revealed peripheral eosinophilia and elevated IgE, consistent with Churg-Strauss syndrome. The patient's symptoms and eosinophilia resolved after an increase in the dose of oral corticosteroids.


CONCLUSIONS
This case describes a unique presentation of conjunctival involvement in CSS that differs from prior case reports by having a small, well-demarcated nodule and lacking signs of active inflammation.
Margolis
Ron
R
Cole Eye Institute, Cleveland Clinic Foundation, Cleveland, OH 44195, USA.
Kosmorsky
Gregory S
GS
Lowder
Careen Y
CY
Schoenfield
Lynn
L
D000328:Adult; D001706:Biopsy; D015267:Churg-Strauss Syndrome / Q000097:blood / Q000150:complications* / Q000188:drug therapy; D003228:Conjunctiva / Q000473:pathology*; D003229:Conjunctival Diseases / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology; D003937:Diagnosis, Differential; D005260:Female; D005500:Follow-Up Studies; D005938:Glucocorticoids / Q000008:administration & dosage / Q000627:therapeutic use; D006801:Humans; D007073:Immunoglobulin E / Q000097:blood
D005938:Glucocorticoids; D007073:Immunoglobulin E