title: Fatal disseminated Acanthamoeba lenticulata infection in a heart transplant patient.
abstract: We report a fatal case of disseminated acanthamebiasis caused by Acanthamoeba lenticulata (genotype T5) in a 39-year-old heart transplant recipient. The diagnosis was based on skin histopathologic results and confirmed by isolation of the ameba from involved skin and molecular analysis of a partial 18S rRNA gene sequence (DF3).
authors.affiliation: Department of Dermatology and Allergy, Hôpital Tenon, Assistance Publique Hôpitaux de Paris, France. stephane.barete@psl.aphp.fr
authors.forename: Stéphane
authors.initials: S
authors.lastname: Barete
authors.forename: Alain
authors.initials: A
authors.lastname: Combes
authors.forename: Johan F
authors.initials: JF
authors.lastname: de Jonckheere
authors.forename: Annick
authors.initials: A
authors.lastname: Datry
authors.forename: Shaïda
authors.initials: S
authors.lastname: Varnous
authors.forename: Valérie
authors.initials: V
authors.lastname: Martinez
authors.forename: Sara García
authors.initials: SG
authors.lastname: Ptacek
authors.forename: Eric
authors.initials: E
authors.lastname: Caumes
authors.forename: Frédérique
authors.initials: F
authors.lastname: Capron
authors.forename: Camille
authors.initials: C
authors.lastname: Francès
authors.forename: Claude
authors.initials: C
authors.lastname: Gibert
authors.forename: Olivier
authors.initials: O
authors.lastname: Chosidow
mesh_terms: D000048:Acanthamoeba / Q000145:classification / Q000235:genetics / Q000472:pathogenicity*; D000328:Adult; D000562:Amebiasis / Q000175:diagnosis / Q000276:immunology / Q000473:pathology; D000818:Animals; D004275:DNA, Ribosomal; D017809:Fatal Outcome; D016027:Heart Transplantation / Q000276:immunology*; D006801:Humans; D016867:Immunocompromised Host; D008297:Male; D008969:Molecular Sequence Data; D012876:Skin Diseases, Parasitic / Q000175:diagnosis / Q000235:genetics / Q000473:pathology*
chemical_list: D004275:DNA, Ribosomal