Macular hole and intravitreal injection of triamcinolone acetonide for macular edema due to central retinal vein occlusion.
OBJECTIVE
To report a case of macular hole progression after intravitreal injection of triamcinolone acetonide (IVTA) for chronic macular edema secondary to nonischemic central retinal vein occlusion (CRVO).


METHODS
A 33-year-old woman with massive macular edema after CRVO underwent IVTA. Optical coherence tomography (OCT) and fluorescein angiography were performed before and after the procedure.


RESULTS
At the 1-week IVTA injection control, the patient's best-corrected visual acuity improved from 20/400 to 20/200 and OCT detected a progression of macular hole stage.


CONCLUSIONS
IVTA steroid injection may provide a significant improvement in macular edema, but injection-related complications may occur such as this uncommon macular reaction resulting in permanent visual loss.
Lattanzio
R
R
Department of Ophthalmology, San Raffaele Scientific Institute, Milano, Italy. lattanzio.rosangela@hsr.it
Ramoni
A
A
Scotti
F
F
Introini
U
U
D000328:Adult; D018450:Disease Progression; D005260:Female; D005451:Fluorescein Angiography; D005938:Glucocorticoids / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D007267:Injections; D008269:Macular Edema / Q000188:drug therapy* / Q000209:etiology; D033401:Microscopy, Acoustic; D012167:Retinal Perforations / Q000139:chemically induced* / Q000175:diagnosis / Q000503:physiopathology; D012170:Retinal Vein Occlusion / Q000150:complications*; D041623:Tomography, Optical Coherence; D014222:Triamcinolone Acetonide / Q000009:adverse effects* / Q000627:therapeutic use; D014792:Visual Acuity; D014822:Vitreous Body
D005938:Glucocorticoids; D014222:Triamcinolone Acetonide