Two new xanthones isolated from the stem bark of Garcinia lancilimba.
Two new xanthones, 1,5,6-trihydroxy-6',6'-dimethyl-2H-pyrano(2',3':3,4)-2-(3-methylbut-2-enyl)xanthone (1) and 1,6,7-trihydroxy-6',6'-dimethyl-2H-pyrano(2',3':3,2)-4-(3-methylbut-2-enyl)xanthone (2), have been isolated from the stem bark of Garcinia lancilimba (Guttiferae), together with six known xanthones. Their structures were identified on the basis of extensive spectral evidence including detailed 2D NMR and HR-MS data. Two new compounds showed moderate inhibitory effect on human breast cancer MDA-MB-435S cell line.
Yang
Nian-Yun
NY
Chinese Medicine Laboratory, Hong Kong Jockey Club Institute of Chinese Medicine, Hong-Kong, PR China.
Han
Quan-Bin
QB
Cao
Xin-Wei
XW
Qiao
Chun-Feng
CF
Song
Jing-Zheng
JZ
Chen
Shi-Lin
SL
Yang
Da-Jian
DJ
Yiu
Hillary
H
Xu
Hong-Xi
HX
D045744:Cell Line, Tumor; D029760:Garcinia / Q000737:chemistry*; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D018547:Plant Stems / Q000737:chemistry*; D021241:Spectrometry, Mass, Electrospray Ionization; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet; D044004:Xanthones / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
D044004:Xanthones