title: [Clinical study of preoperative analgesia for liposuction].
abstract: OBJECTIVE
  To observe the effect of the preoperative analgesia with Oxycodone/Acetaminophen for liposuction.
  
  
  METHODS
  In the double-blind, placebo-controlled clinical trial, 40 patients undergoing the liposuction were randomly assigned into two groups which were received a single oral dose of Oxycodone/Acetaminophen or calcium gluconate respectively before the operation. The degrees of pain were evaluated by visual analogue scale (VAS) at the beginning and the end of the operation. Adverse effects and the overall satisfaction on analgesic therapy were assessed when operation finished.
  
  
  RESULTS
  The VAS scores of the experimental group were significantly lower than the control group at the beginning and the end of operation (P < 0.05). There were no significant differences between the two groups in side effects (P > 0.05).
  
  
  CONCLUSIONS
  Oxycodone/Acetaminophen could produce preemptive effect. Preoperative oral administration of Oxycodone/ Acetaminophen may provide patients with good analgesia in plastic and cosmetic operation.
authors.affiliation: Department of Plastic Surgery of Peking Union Medical College Hospital, Chinese Academy of Medical Science, Beijing 100032, China.
authors.forename: Zhi-Fei
authors.initials: ZF
authors.lastname: Liu
authors.forename: Xiao-Jun
authors.initials: XJ
authors.lastname: Wang
authors.forename: Xian-Cheng
authors.initials: XC
authors.lastname: Wang
authors.forename: Lin
authors.initials: L
authors.lastname: Zhu
authors.forename: Qun
authors.initials: Q
authors.lastname: Qiao
mesh_terms: D000328:Adult; D000698:Analgesia / Q000379:methods*; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D015187:Lipectomy / Q000379:methods*; D008875:Middle Aged; D055815:Young Adult