title: The asymmetric vinylogous Mannich reaction of dicyanoalkylidenes with alpha-amido sulfones under phase-transfer conditions.
abstract: The stereoselective vinylogous Mannich reaction of dicyanoalkylidenes under phase-transfer catalytic conditions utilizing stable alpha-amido sulfones as imine precursors is presented; a rigid pyrrolidinium salt acts as the phase-transfer catalyst, giving access to the amino alkylated products in generally good yield and up to 95% ee.
authors.affiliation: Danish National Research Foundation: Center for Catalysis, Department of Chemistry, Aarhus University, Aarhus C, DK-8000, Denmark.
authors.forename: Barbara
authors.initials: B
authors.lastname: Niess
authors.forename: Karl Anker
authors.initials: KA
authors.lastname: Jørgensen