Synthesis of chinensines A-E.
Short and efficient syntheses of coronarin E (4) and chinensines A-E (5-9) have been accomplished. The use of two different types of reaction of singlet oxygen ((1)O(2)) lies at the heart of the synthetic strategy. The syntheses have facilitated the clarification of certain previously unknown, or unconfirmed, stereochemical details (the relativity stereochemistries of chinensines D and E and the absolute stereochemistries for all the synthesized family members).
Margaros
Ioannis
I
Department of Chemistry, University of Crete, Vasilika Vouton, 71003 Iraklion, Crete, Greece.
Vassilikogiannakis
Georgios
G
D001688:Biological Products / Q000138:chemical synthesis* / Q000737:chemistry; D004224:Diterpenes / Q000138:chemical synthesis / Q000737:chemistry; D007783:Lactones / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D009281:Naphthalenes / Q000138:chemical synthesis* / Q000737:chemistry; D010100:Oxygen / Q000737:chemistry
D001688:Biological Products; D004224:Diterpenes; D007783:Lactones; D009281:Naphthalenes; C482830:coronarin E; D010100:Oxygen