title: [Detection of Helicobacter pylori in oral cavity of patients with recurrent aphthous ulcer].
abstract: OBJECTIVE
  To investigate the association of recurrent aphthous ulcer (RAU) with Helicobacter pylori (Hp) infection and digestive diseases.
  
  
  METHODS
  Saliva samples were collected from 82 patients with RAU and 74 healthy volunteers for Hp detection with PCR.
  
  
  RESULTS
  The positivity rates of HP differed significantly between RAU patients and healthy volunteers (43.9% vs 16.2%, P<0.001). In the 82 RAU patients, 22 (26.82%) were identified to have gastritis and peptic ulcer, whereas only 7 out of the 74 healthy volunteers (10.45%) had such digestive diseases, showing significant difference between them (P<0.01).
  
  
  CONCLUSIONS
  Hp might in some way associate with RAU, which in turn is associated with an increased incidence of digestive diseases.
authors.affiliation: Department of Stomatology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
authors.forename: Bao-jun
authors.initials: BJ
authors.lastname: Long
authors.forename: Ke
authors.initials: K
authors.lastname: Chen
authors.forename: Bu-ling
authors.initials: BL
authors.lastname: Wu
authors.forename: Jian-min
authors.initials: JM
authors.lastname: Duan
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D005260:Female; D005756:Gastritis / Q000382:microbiology; D016481:Helicobacter Infections / Q000175:diagnosis*; D016480:Helicobacter pylori / Q000302:isolation & purification*; D006801:Humans; D008297:Male; D009055:Mouth / Q000382:microbiology*; D010437:Peptic Ulcer / Q000382:microbiology; D016133:Polymerase Chain Reaction; D012008:Recurrence; D012463:Saliva / Q000382:microbiology; D013281:Stomatitis, Aphthous / Q000382:microbiology*