title: Pulmonary computed tomography findings of visceral larva migrans caused by Ascaris suum.
abstract: OBJECTIVE
  To retrospectively evaluate the computed tomography (CT) findings of pulmonary involvement in patients with visceral larva migrans caused by Ascaris suum.
  
  
  METHODS
  Institutional review board approval was obtained, and informed consent was waived. Chest CT scans obtained between January 1994 and November 2005 in 32 patients infected with A. suum were retrospectively evaluated by 3 chest radiologists. In 4 patients who underwent surgical or transbronchial biopsy, comparisons of the CT images with the actual specimens were performed.
  
  
  RESULTS
  On CT scans, abnormal findings were seen in 28 patients. The most common abnormality consisted of nodules (n = 19) in which the majority had a halo of ground-glass attenuation (n = 17), followed by ground-glass attenuation (n = 18), and interlobular septal thickening (n = 14). These abnormalities were predominantly seen in the peripheral lung (n = 25). Of the 7 patients who underwent follow-up CT scans, nodules (n = 6) and ground-glass attenuation (n = 5) had migrated in 4 patients. Pathologically, these findings corresponded to marked eosinophilic infiltration into the interstitium.
  
  
  CONCLUSIONS
  These CT findings are considered to be suggestive of thoracic involvement in patients with visceral larva migrans caused by A. suum.
authors.affiliation: Department of Diagnostic and Interventional Radiology, Oita University Faculty of Medicine, Oita, Japan. fumitook@med.oita-u.ac.jp
authors.forename: Fumito
authors.initials: F
authors.lastname: Okada
authors.forename: Asami
authors.initials: A
authors.lastname: Ono
authors.forename: Yumiko
authors.initials: Y
authors.lastname: Ando
authors.forename: Shinji
authors.initials: S
authors.lastname: Yotsumoto
authors.forename: Sachie
authors.initials: S
authors.lastname: Yotsumoto
authors.forename: Shuichi
authors.initials: S
authors.lastname: Tanoue
authors.forename: Shunro
authors.initials: S
authors.lastname: Matsumoto
authors.forename: Masaki
authors.initials: M
authors.lastname: Wakisaka
authors.forename: Hiromu
authors.initials: H
authors.lastname: Mori
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000818:Animals; D017165:Ascaris suum; D003287:Contrast Media; D005260:Female; D006801:Humans; D007816:Larva Migrans, Visceral / Q000000981:diagnostic imaging* / Q000473:pathology; D008174:Lung Diseases, Parasitic / Q000000981:diagnostic imaging* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed / Q000379:methods*
chemical_list: D003287:Contrast Media