title: Perioperative management of patients with coronary stents.
abstract: Perioperative coronary stent thrombosis is a catastrophic complication that can occur in patients receiving both bare-metal and drug-eluting stents. Noncardiac surgery appears to increase the risk that recently-placed stents thrombose, especially when surgery is performed early after stenting, and particularly if dual antiplatelet therapy is discontinued. We reviewed the existing data about the frequency of stent thrombosis after noncardiac surgery and explored the impact of delay from surgery and discontinuation of antiplatelet therapy. We also reviewed the data about the impact of preoperative revascularization in patients known to require noncardiac surgery. Based on these published data, we offer recommendations that can be used to guide the treatment of patients who require noncardiac surgery after having received a stent.
authors.affiliation: Division of Cardiovascular Diseases, University of Texas Southwestern Medical Center, and Dallas VA Medical Center, Dallas, Texas 75216, USA. emmanouil.brilakis@utsouthwestern.edu
authors.forename: Emmanouil S
authors.initials: ES
authors.lastname: Brilakis
authors.forename: Subhash
authors.initials: S
authors.lastname: Banerjee
authors.forename: Peter B
authors.initials: PB
authors.lastname: Berger
mesh_terms: D003328:Coronary Thrombosis / Q000188:drug therapy / Q000517:prevention & control*; D006801:Humans; D009204:Myocardial Revascularization / Q000379:methods; D019990:Perioperative Care / Q000379:methods*; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use; D017410:Practice Guidelines as Topic; D015607:Stents / Q000009:adverse effects*
chemical_list: D010975:Platelet Aggregation Inhibitors