title: Inherited renal acidoses.
abstract: Inherited acidosis may result from a primary renal defect in acid-base handling, emphasizing the central role of the kidney in control of body pH; as a secondary phenomenon resulting from abnormal renal electrolyte handling; or from excess production of acid elsewhere in the body. Here, we review our current understanding of the inherited renal acidoses at a genetic and molecular level.
authors.affiliation: Department of Medical Genetics and Division of Renal Medicine, University of Cambridge, Cambridge Institute for Medical Research, UK.
authors.forename: Andrew C
authors.initials: AC
authors.lastname: Fry
authors.forename: Fiona E
authors.initials: FE
authors.lastname: Karet
mesh_terms: D000137:Acid-Base Imbalance / Q000235:genetics* / Q000378:metabolism*; D000141:Acidosis, Renal Tubular / Q000235:genetics* / Q000378:metabolism*; D000818:Animals; D006801:Humans; D007684:Kidney Tubules / Q000378:metabolism*