title: Granulomatous jellyfish dermatitis.
abstract: The induction of a granulomatous inflammation by jellyfish toxins is rare. More typically, acute toxic and urticarial reactions are seen. An 11-year-old boy developed a striated urticarial erythema on the left cheek after contact with a gelatinous mass while swimming in the sea in Croatia. After initial erosion, a striated induration developed in the area of contact. Histological examination revealed a granulomatous inflammation with some eosinophils. While topical steroid-based antiinflammatory and antibacterial therapy over several weeks was not effective, topical therapy with tacrolimus 0.1% for two two-week treatment periods led to healing of the skin changes with a slight scar. There was no clinical recurrence after 5 month of follow-up.
authors.affiliation: Department of Dermatology, University of Regensburg, Germany. heidi.ulrich@klinik.uni-regensburg.de
authors.forename: Heidi
authors.initials: H
authors.lastname: Ulrich
authors.forename: Michael
authors.initials: M
authors.lastname: Landthaler
authors.forename: Thomas
authors.initials: T
authors.lastname: Vogt
mesh_terms: D000818:Animals; D001733:Bites and Stings / Q000150:complications*; D002648:Child; D003064:Cnidarian Venoms / Q000633:toxicity*; D003877:Dermatitis, Contact / Q000188:drug therapy* / Q000209:etiology*; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008297:Male; D037401:Scyphozoa; D016559:Tacrolimus / Q000627:therapeutic use*; D016896:Treatment Outcome
chemical_list: D003064:Cnidarian Venoms; D007166:Immunosuppressive Agents; D016559:Tacrolimus