title: Mucocutaneous nasal histoplasmosis in an immunocompetent young adult.
abstract: A case of mucocutaneous nasal histoplasmosis in an immunocompetent host is described below. A 30-year-old male had a broadened nose with swelling and repeated blockage of nasal passages for the past six months. Diagnosis was made on the basis of histological demonstration of characteristic yeast cells of Histoplasma capsulatum var. capsulatum occurring within histiocytes and extracellularly in stained smears of fine needle aspirates and biopsy from the lesions in ala of the nose and perioral region. The patient showed appreciable regression of lesions after three weeks of itraconazole therapy but was not available for re-assessment.
authors.affiliation: Department of Pathology and Dermatology, Deen Dayal Upadhayay Hospital, Hari Nagar, New Delhi, India.
authors.forename: Neelam
authors.initials: N
authors.lastname: Sood
authors.forename: Harish C
authors.initials: HC
authors.lastname: Gugnani
authors.forename: Rashmi
authors.initials: R
authors.lastname: Batra
authors.forename: V
authors.initials: V
authors.lastname: Ramesh
authors.forename: Arvind A
authors.initials: AA
authors.lastname: Padhye
mesh_terms: D000328:Adult; D003881:Dermatomycoses / Q000276:immunology / Q000473:pathology*; D006660:Histoplasmosis / Q000276:immunology / Q000473:pathology*; D006801:Humans; D007121:Immunocompetence; D008297:Male; D009297:Nasal Mucosa; D009668:Nose Diseases / Q000276:immunology / Q000382:microbiology* / Q000473:pathology*