Merodrimanes and other constituents from Talaromyces thailandiasis.
Chemical study of a previously undescribed fungus, Talaromyces thailandiasis, furnished the two new merodrimanes thailandolides A (1) and B (2), an O-methylated derivative (3) of the aromatic fragment incorporated in thailandolide B, and three known closely related 1(3H)-isobenzofuran derivatives, penisimplicissin (4a), vermistatin (4b), and hydroxydihydrovermistatin (4c). Structures were established by spectroscopic measurements and confirmed by X-ray analyses of compounds 1 and 4b. The unusual peptide analogue N-benzoylphenylalanyl-N-benzoylphenyl alaninate (5) isolated earlier from a higher plant was also found.
Dethoup
Tida
T
Department of Plant Pathology, Faculty of Agriculture, Kasetsart University, Bangkok, Thailand.
Manoch
Leka
L
Kijjoa
Anake
A
Pinto
Madalena
M
Gales
Luis
L
Damas
Ana Margarida
AM
Silva
Artur M S
AM
Eaton
Graham
G
Herz
Werner
W
D018360:Crystallography, X-Ray; D008968:Molecular Conformation; D015394:Molecular Structure; D012717:Sesquiterpenes / Q000737:chemistry / Q000302:isolation & purification*; D032901:Talaromyces / Q000737:chemistry*; D013785:Thailand
D012717:Sesquiterpenes; C522150:thailandolide A; C522151:thailandolide B