[Very late intrastent thrombosis--at 27 months!].
Interrupting platelet antiaggregant therapy in coronary patients treated by stenting exposes them to the risk of cardiac complications. The risk of acute thrombosis of the stent is well known but late intrastent thrombosis is less common and mainly observed with drug eluting stents. The authors report the case of a 54 year old man who had thrombosis of an ordinary stent implanted 27 months previously which occurred in the immediate post-operative period after repair of an inguinal hernia. The interruption of platelet antiaggregant therapy was relayed by flurbiprofen in accordance with recommendations of scientific societies. After a review of the literature, the authors discuss late stent thrombosis and interruption of platelet aggregant therapy in coronary patients before non-cardiac surgery.
Digne
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F
Unlté de cardiologie interventionnelle, Clinique Ambroise Paré, 25-27 boulevard Victor Hugo, 92200 Neuilly-sur-Seine.
Gérardin
B
B
Pillière
R
R
Estagnasié
P
P
Dib
J C
JC
Terdjman
M
M
Grinda
J M
JM
Dubois
C
C
D001241:Aspirin / Q000008:administration & dosage / Q000627:therapeutic use; D000077144:Clopidogrel; D003328:Coronary Thrombosis / Q000209:etiology*; D017809:Fatal Outcome; D005480:Flurbiprofen / Q000008:administration & dosage / Q000627:therapeutic use; D005500:Follow-Up Studies; D006552:Hernia, Inguinal / Q000601:surgery*; D006801:Humans; D010535:Laparoscopy; D008297:Male; D008875:Middle Aged; D010975:Platelet Aggregation Inhibitors / Q000008:administration & dosage / Q000627:therapeutic use; D011183:Postoperative Complications; D015607:Stents; D013988:Ticlopidine / Q000008:administration & dosage / Q000031:analogs & derivatives / Q000627:therapeutic use
D010975:Platelet Aggregation Inhibitors; D005480:Flurbiprofen; D000077144:Clopidogrel; D013988:Ticlopidine; D001241:Aspirin