title: Infective endocarditis at a tertiary care centre in Saudi Arabia: review of 47 cases over 10 years.
abstract: To describe the pattern of infective endocarditis in a tertiary hospital in Riyadh, Saudi Arabia, a retrospective review was made of all cases admitted between 1993 and 2003. Of 47 patients, a native valve was involved in 37 (78.7%) and a prosthetic valve in 10 (21.3%). Predisposing cardiac conditions were present in 27 patients: rheumatic and congenital heart disease were the most common. Blood cultures were positive in 76.4% of patients: the most commonly isolated organisms were Staphylococcus spp. in 20 patients (12 Sta. aureus and 8 coagulase-negative staphylococci) and Enterococcus spp. (6 patients). The complication rate was 78.7% and hospital mortality rate was 8.5%.
authors.affiliation: Division of Infectious Diseases, Department of Medicine, King Abdulaziz Medical City, Riyadh, Saudi Arabia.
authors.forename: A
authors.initials: A
authors.lastname: Nashmi
authors.forename: Z A
authors.initials: ZA
authors.lastname: Memish
mesh_terms: D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000368:Aged; D000900:Anti-Bacterial Agents; D015984:Causality; D002648:Child; D002675:Child, Preschool; D017548:Echocardiography, Transesophageal; D004617:Embolism / Q000382:microbiology; D004697:Endocarditis, Bacterial / Q000175:diagnosis / Q000453:epidemiology* / Q000209:etiology / Q000628:therapy; D005260:Female; D006333:Heart Failure / Q000382:microbiology; D019918:Heart Valve Prosthesis Implantation; D017052:Hospital Mortality; D006772:Hospitals, Military; D006801:Humans; D007223:Infant; D017053:Infection Control; D008297:Male; D008875:Middle Aged; D011159:Population Surveillance; D051437:Renal Insufficiency / Q000382:microbiology; D012189:Retrospective Studies; D012529:Saudi Arabia / Q000453:epidemiology; D017678:Sex Distribution
chemical_list: D000900:Anti-Bacterial Agents