title: In vivo dosimeters for HDR brachytherapy: a comparison of a diamond detector, MOSFET, TLD, and scintillation detector.
abstract: The large dose gradients in brachytherapy necessitate a detector with a small active volume for accurate dosimetry. The dosimetric performance of a novel scintillation detector (BrachyFOD) is evaluated and compared to three commercially available detectors, a diamond detector, a MOSFET, and LiF TLDs. An 192Ir HDR brachytherapy source is used to measure the depth dependence, angular dependence, and temperature dependence of the detectors. Of the commercially available detectors, the diamond detector was found to be the most accurate, but has a large physical size. The TLDs cannot provide real time readings and have depth dependent sensitivity. The MOSFET used in this study was accurate to within 5% for distances of 20 to 50 mm from the 192Ir source in water but gave errors of 30%-40% for distances greater than 50 mm from the source. The BrachyFOD was found to be accurate to within 3% for distances of 10 to 100 mm from an HDR 192Ir brachytherapy source in water. It has an angular dependence of less than 2% and the background signal created by Cerenkov radiation and fluorescence of the plastic optical fiber is insignificant compared to the signal generated in the scintillator. Of the four detectors compared in this study the BrachyFOD has the most favorable combination of characteristics for dosimetry in HDR brachytherapy.
authors.affiliation: School of Physics, The University of Sydney, NSW 2006 Australia. jlambert@Physics.usyd.edu.au
authors.forename: Jamil
authors.initials: J
authors.lastname: Lambert
authors.forename: Tatsuya
authors.initials: T
authors.lastname: Nakano
authors.forename: Sue
authors.initials: S
authors.lastname: Law
authors.forename: Justin
authors.initials: J
authors.lastname: Elsey
authors.forename: David R
authors.initials: DR
authors.lastname: McKenzie
authors.forename: Natalka
authors.initials: N
authors.lastname: Suchowerska
mesh_terms: D016880:Anisotropy; D001918:Brachytherapy / Q000379:methods*; D006801:Humans; D007496:Iridium Radioisotopes / Q000627:therapeutic use*; D019047:Phantoms, Imaging; D011874:Radiometry; D019275:Radiopharmaceuticals / Q000627:therapeutic use; D013696:Temperature
chemical_list: D007496:Iridium Radioisotopes; D019275:Radiopharmaceuticals