Informal caregiving burden in advanced non-small cell lung cancer: the HABIT study.
BACKGROUND
This study's aim was to assess economic data regarding the home assistance burden for advanced non-small cell lung cancer (NSCLC) patients in Italy.


METHODS
One hundred four NSCLC patients in second-line chemotherapy (2LC) or in supportive therapy (ST) were enrolled in 18 Italian oncology departments and were observed for 3 months. The main caregiver's workload was assessed monthly by a task scale; other caregivers' activities were also registered. Eastern Cooperative Oncology Group performance status was assessed by physicians, and patients completed the Lung Cancer Symptoms (LCS) subscale. Formal caregiving time was valued according to market prices; informal caregiving hours were valued using the wage rate for an equivalent service. Covariance analysis was performed to check for influential factors in assistance costs.


RESULTS
The mean age of the total sample was 65.5 years, and prevalence of males was over 80%. In over 70% of cases, the principal caregiver was patient's spouse, living with the patient and not working. Principal caregiver support was the main cost item: 2.368 euros in 2LC and 2.805 euros in ST, representing 74% of total trimonthly assistance costs. Regression analysis showed a positive correlation between the severity of symptoms and the costs of assistance. The caregiving burden was higher in patients with bone and/or cerebral metastases; other metastasis sites seemed to have no impact on assistance costs.


CONCLUSIONS
Considering quality of life as the ultimate health outcome, clinicians are challenged to contribute to a research and policy agenda that holds burden of care in due consideration.
Gridelli
Cesare
C
Division of Medical Oncology, S.G. Moscati Hospital, Avellino, Italy. cgridelli@libero.it
Ferrara
Carmine
C
Guerriero
Ciro
C
Palazzo
Salvatore
S
Grasso
Giuseppe
G
Pavese
Ida
I
Satta
Francesco
F
Bajetta
Emilio
E
Cortinovis
Diego
D
Barbieri
Fausto
F
Gebbia
Vittorio
V
Grossi
Francesco
F
Novello
Silvia
S
Baldini
Editta
E
Gasparini
Giampietro
G
Latino
Walter
W
Durante
Emilia
E
Giustini
Lucio
L
Negrini
Cristina
C
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000970:Antineoplastic Agents / Q000627:therapeutic use; D002289:Carcinoma, Non-Small-Cell Lung / Q000188:drug therapy / Q000191:economics* / Q000453:epidemiology; D017028:Caregivers / Q000191:economics* / Q000523:psychology; D017281:Cost of Illness; D003365:Costs and Cost Analysis; D005260:Female; D017048:Health Care Costs; D006701:Home Nursing / Q000191:economics*; D006801:Humans; D007558:Italy / Q000453:epidemiology; D008175:Lung Neoplasms / Q000188:drug therapy / Q000191:economics* / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D011788:Quality of Life; D012944:Social Support; D012959:Socioeconomic Factors
D000970:Antineoplastic Agents