Genetic maps of the proximal half of chromosome arm 2L of Drosophila melanogaster.
Drosophila mutants have played an important role in elucidating the physiologic function of genes. Large-scale projects have succeeded in producing mutations in a large proportion of Drosophila genes. Many mutant fly lines have also been produced through the efforts of individual laboratories over the past century. In an effort to make some of these mutants more useful to the research community, we systematically mapped a large number of mutations affecting genes in the proximal half of chromosome arm 2L to more precisely defined regions, defined by deficiency intervals, and, when possible, by individual complementation groups. To further analyze regions 36 and 39-40, we produced 11 new deficiencies with gamma irradiation, and we constructed 6 new deficiencies in region 30-33, using the DrosDel system. trans-heterozygous combinations of deficiencies revealed 5 additional functions, essential for viability or fertility.
Levine
Sylvia Glen
SG
Dept. of Biology, McGill University, 1205 Avenue Docteur Penfield, Montreal, Quebec, H3A 1B1, Canada.
Sunday
Suchot
S
Dörig
Ruth E
RE
Suter
Beat
B
Lasko
Paul
P
D000818:Animals; D001665:Binding Sites; D002874:Chromosome Mapping; D003433:Crosses, Genetic; D004252:DNA Mutational Analysis; D004331:Drosophila melanogaster / Q000235:genetics*; D005260:Female; D005298:Fertility; D017344:Genes, Insect; D008297:Male; D008957:Models, Genetic; D009154:Mutation; D010641:Phenotype; D013696:Temperature