title: Occurrence of "J waves" in 12-lead ECG as a marker of acute ischemia and their cellular basis.
abstract: The "J wave" (also referred to as "the Osborn wave,""the J deflection," or "the camel's hump") is a distinctive deflection occurring at the QRS-ST junction. In 1953, Dr. John Osborn described the "J wave" as an "injury current" resulting in ventricular fibrillation during experimental hypothermia. Although "J Wave" is supposed to be pathognomonic of hypothermia, it is seen in a host of other conditions such as hypercalcemia, brain injury, subarachnoid hemorrhage, cardiopulmonary arrest from over sedation, the Brugada syndrome, vasospastic angina, and idiopathic ventricular fibrillation. However, there is paucity of literature data as regards to ischemic etiology of "J Wave." In this article, we present a case where "J waves" were probably induced by ischemia. We also discuss the mechanism of ischemia-induced "J wave" accentuation and its prognostic implications.
authors.affiliation: Department of Cardiology, Grant Medical Foundation, Ruby Hall Clinic, Pune, Maharashtra 411001, India.
authors.forename: Rituparna
authors.initials: R
authors.lastname: Shinde
authors.forename: Shinde
authors.initials: S
authors.lastname: Rituparna
authors.forename: Suresh
authors.initials: S
authors.lastname: Shinde
authors.forename: Shinde
authors.initials: S
authors.lastname: Suresh
authors.forename: Chandrashekhar
authors.initials: C
authors.lastname: Makhale
authors.forename: Makhale
authors.initials: M
authors.lastname: Chandrashekhar
authors.forename: Purvez
authors.initials: P
authors.lastname: Grant
authors.forename: Grant
authors.initials: G
authors.lastname: Purvez
authors.forename: Sunil
authors.initials: S
authors.lastname: Sathe
authors.forename: Sathe
authors.initials: S
authors.lastname: Sunil
authors.forename: Manuel
authors.initials: M
authors.lastname: Durairaj
authors.forename: M
authors.initials: M
authors.lastname: Durairaj
authors.forename: Yash
authors.initials: Y
authors.lastname: Lokhandwala
authors.forename: Lokhandwala
authors.initials: L
authors.lastname: Yash
authors.forename: Jose
authors.initials: J
authors.lastname: Di Diego
authors.forename: J M
authors.initials: JM
authors.lastname: DI Diego
authors.forename: Charles
authors.initials: C
authors.lastname: Antzelevitch
authors.forename: Antzelevitch
authors.initials: A
authors.lastname: Charles
mesh_terms: D000208:Acute Disease; D000328:Adult; D004562:Electrocardiography; D006801:Humans; D008297:Male; D017202:Myocardial Ischemia / Q000473:pathology / Q000503:physiopathology*