title: Exercise effect on weight and body fat in men and women.
abstract: OBJECTIVE
  The effect of national exercise recommendations on adiposity is unknown and may differ by sex. We examined long-term effects of aerobic exercise on adiposity in women and men.
  
  
  METHODS
  This was a 12-month randomized, controlled clinical trial testing exercise effect on weight and body composition in men (N = 102) and women (N = 100). Sedentary/unfit persons, 40 to 75 years old, were recruited through physician practices and media. The intervention was facility- and home-based moderate-to-vigorous intensity aerobic activity, 60 min/d, 6 days/wk vs. controls (no intervention).
  
  
  RESULTS
  Exercisers exercised a mean 370 min/wk (men) and 295 min/wk (women), and seven dropped the intervention. Exercisers lost weight (women, -1.4 vs. +0.7 kg in controls, p = 0.008; men, -1.8 vs. -0.1 kg in controls, p = 0.03), BMI (women, -0.6 vs. +0.3 kg/m(2) in controls, p = 0.006; men, -0.5 kg/m(2) vs. no change in controls, p = 0.03), waist circumference (women, -1.4 vs. +2.2 cm in controls, p < 0.001; men, -3.3 vs. -0.4 cm in controls, p = 0.003), and total fat mass (women, -1.9 vs. +0.2 kg in controls, p = 0.001; men, -3.0 vs. +0.2 kg in controls, p < 0.001). Exercisers with greater increases in pedometer-measured steps per day had greater decreases in weight, BMI, body fat, and intra-abdominal fat (all p trend < 0.05 in both men and women). Similar trends were observed for increased minutes per day of exercise and for increases in maximal oxygen consumption.
  
  
  CONCLUSIONS
  These data support the U.S. Department of Agriculture and Institute of Medicine guidelines of 60 min/d of moderate-to-vigorous physical activity.
authors.affiliation: Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue N, M4-B402, Seattle, WA 98109-1024, USA. amctiern@fhcrc.org
authors.forename: Anne
authors.initials: A
authors.lastname: McTiernan
authors.forename: Bess
authors.initials: B
authors.lastname: Sorensen
authors.forename: Melinda L
authors.initials: ML
authors.lastname: Irwin
authors.forename: Angela
authors.initials: A
authors.lastname: Morgan
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Yasui
authors.forename: Rebecca E
authors.initials: RE
authors.lastname: Rudolph
authors.forename: Christina
authors.initials: C
authors.lastname: Surawicz
authors.forename: Johanna W
authors.initials: JW
authors.lastname: Lampe
authors.forename: Paul D
authors.initials: PD
authors.lastname: Lampe
authors.forename: Kamran
authors.initials: K
authors.lastname: Ayub
authors.forename: John D
authors.initials: JD
authors.lastname: Potter
mesh_terms: D000273:Adipose Tissue; D000328:Adult; D000367:Age Factors; D000368:Aged; D000465:Algorithms; D001823:Body Composition; D050218:Body Fat Distribution; D015992:Body Mass Index; D001835:Body Weight; D015444:Exercise / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010349:Patient Compliance; D012727:Sex Characteristics; D016037:Single-Blind Method