title: Insecticide resistance in disease vectors of public health importance.
abstract: Vector-borne diseases are a global problem--a trend that may only increase if global temperature rises and demographic trends continue--and their economic and social impact are enormous. Insecticides play a vital role in the fight against these diseases by controlling the vectors themselves in order to improve public health; however, resistance to commonly used insecticides is on the rise. This perspective outlines the major classes of disease vector control agents and the mechanisms of resistance that have evolved, arguing that effective resistance management strategies must carefully monitor resistance in field populations and use combinations of the limited modes of action available to best effect. Moreover, the development of novel insecticide classes for control of adult mosquitoes and other vectors becomes increasingly important.
authors.affiliation: Bayer CropScience AG, Research, Biology Insecticides, Alfred Nobel Str. 50, D-40789 Monheim, Germany. ralf.nauen@bayercropscience.com
authors.forename: Ralf
authors.initials: R
authors.lastname: Nauen
mesh_terms: D000818:Animals; D009033:Culicidae / Q000502:physiology*; D007303:Insect Vectors / Q000502:physiology*; D007305:Insecticide Resistance / Q000502:physiology*; D007306:Insecticides; D009032:Mosquito Control / Q000379:methods
chemical_list: D007306:Insecticides