Botulinum toxin for the treatment of spasticity in children: attainment of treatment goals.
Forty patients (mean age 5 years) with a spastic disorder treated by botulinum injections (53 sessions) were evaluated for functional outcome in terms of achievement of their individual predetermined goals of treatment, rated on a modified Goal Attainment Scale from 1 (worsening function) to 4 (improved gross motor function). At the 2-week follow-up, 40% had a score of 1, 33% a score of 2, and 13% a score of 3; 12% showed no functional change. Botulinum treatments failed to significantly improve the gross motor function in this patient group. Treatment goals and expectations should clearly be established beforehand.
Weigl
Daniel M
DM
Pediatric Orthopedic Unit, Schneider Children's Medical Center of Israel, Petah Tiqwa, Israel. dweigl@bezeqint.net
Arbel
Nili
N
Katz
Kalman
K
Becker
Tali
T
Bar-On
Elhanan
E
D000293:Adolescent; D019274:Botulinum Toxins, Type A / Q000627:therapeutic use*; D002547:Cerebral Palsy / Q000145:classification / Q000188:drug therapy* / Q000503:physiopathology; D002648:Child; D002675:Child, Preschool; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D035002:Lower Extremity / Q000503:physiopathology; D008297:Male; D009128:Muscle Spasticity / Q000188:drug therapy / Q000503:physiopathology; D009465:Neuromuscular Agents / Q000627:therapeutic use*; D016896:Treatment Outcome
D009465:Neuromuscular Agents; D019274:Botulinum Toxins, Type A