title: The discovery of basic fibroblast growth factor/fibroblast growth factor-2 and its role in haematological malignancies.
abstract: Basic fibroblast growth factor/fibroblast growth factor-2 is one of the best characterized of the pro-angiogenic cytokines. This review describes its history, as well as its role in tumor angiogenesis associated with haematological malignancies, as traced by the main contributions to the international medical literature.
authors.affiliation: Department of Human Anatomy and Histology, University of Bari Medical School, Bari, Italy. ribatti@anatomia.uniba.it
authors.forename: Domenico
authors.initials: D
authors.lastname: Ribatti
authors.forename: Angelo
authors.initials: A
authors.lastname: Vacca
authors.forename: Marco
authors.initials: M
authors.lastname: Rusnati
authors.forename: Marco
authors.initials: M
authors.lastname: Presta
mesh_terms: D000818:Animals; D045744:Cell Line, Tumor; D016222:Fibroblast Growth Factor 2 / Q000378:metabolism* / Q000502:physiology*; D015972:Gene Expression Regulation, Neoplastic; D019337:Hematologic Neoplasms / Q000378:metabolism*; D006801:Humans; D008223:Lymphoma / Q000378:metabolism; D008954:Models, Biological; D009389:Neovascularization, Pathologic; D017468:Receptors, Fibroblast Growth Factor / Q000378:metabolism
chemical_list: D017468:Receptors, Fibroblast Growth Factor; D016222:Fibroblast Growth Factor 2