title: [Diagnosis and management of deep venous thrombosis].
abstract: Deep-vein thrombosis (DVT) is a common condition that can lead to complications such as postphlebitic syndrome, pulmonary embolism and death. Currently, an algorithm strategy combining pretest probability, D-dimer testing and compression ultrasonography imaging allows for safe and convenient estimation of suspected lower-limb thrombosis. The mainstay of treatment is anticoagulation therapy. The use of low-molecular-weight heparin or pentasaccharide (fondaparinux) allows for outpatient management of most patients with DVT. The duration of anticoagulation depends on whether the primary event was idiopathic or secondary to a transient risk factor. Interventions such as thrombolysis and placement of inferior vena cava filter are reserved for special situations.
authors.affiliation: Servicio de Hematología, Clínica Universitaria, Facultad de Medicina, Universidad de Navarra, España. japaramo@unav.es
authors.forename: J A
authors.initials: JA
authors.lastname: Páramo
authors.forename: E Ruiz
authors.initials: ER
authors.lastname: de Gaona
authors.forename: R
authors.initials: R
authors.lastname: García
authors.forename: P
authors.initials: P
authors.lastname: Rodríguez
authors.forename: R
authors.initials: R
authors.lastname: Lecumberri
mesh_terms: D000465:Algorithms; D005338:Fibrin Fibrinogen Degradation Products / Q000032:analysis; D005343:Fibrinolytic Agents / Q000627:therapeutic use; D000077425:Fondaparinux; D006495:Heparin, Low-Molecular-Weight / Q000627:therapeutic use; D006801:Humans; D011134:Polysaccharides / Q000627:therapeutic use; D011655:Pulmonary Embolism / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology / Q000517:prevention & control; D012008:Recurrence; D015912:Thrombolytic Therapy; D019851:Thrombophilia / Q000188:drug therapy / Q000209:etiology; D013924:Thrombophlebitis / Q000150:complications / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000601:surgery; D018608:Ultrasonography, Doppler; D016306:Vena Cava Filters; D020246:Venous Thrombosis / Q000175:diagnosis* / Q000188:drug therapy* / Q000517:prevention & control / Q000601:surgery
chemical_list: D005338:Fibrin Fibrinogen Degradation Products; D005343:Fibrinolytic Agents; D006495:Heparin, Low-Molecular-Weight; D011134:Polysaccharides; C036309:fibrin fragment D; D000077425:Fondaparinux