title: Excision of the tricuspid valve in a baby with Candida endocarditis.
abstract: We report on the management of Candida endocarditis in a 5-month old infant. The orifice of the tricuspid valve was totally obstructed, and the tension apparatus of the valve destroyed. Excision of the valve led to severe failure of the right heart. The combined use of anti-failure treatment, and reduction of right ventricular afterload with oxygen, nitric oxide and sildenafil, proved successful.
authors.affiliation: Department of Paediatric Cardiology, Erasmus Medical Centre, Sophia Children's Hospital, Rotterdam, The Netherlands. f.duplessis@erasmusmc.nl
authors.forename: Frederik A
authors.initials: FA
authors.lastname: du Plessis
authors.forename: Willem A
authors.initials: WA
authors.lastname: Helbing
authors.forename: Ad J J C
authors.initials: AJ
authors.lastname: Bogers
mesh_terms: D000935:Antifungal Agents / Q000627:therapeutic use; D002177:Candidiasis / Q000601:surgery*; D004696:Endocarditis / Q000601:surgery*; D005260:Female; D015725:Fluconazole / Q000627:therapeutic use; D006333:Heart Failure / Q000209:etiology; D006801:Humans; D007223:Infant; D009569:Nitric Oxide / Q000627:therapeutic use; D010102:Oxygen Inhalation Therapy; D010879:Piperazines / Q000627:therapeutic use; D011183:Postoperative Complications; D011687:Purines / Q000627:therapeutic use; D000068677:Sildenafil Citrate; D013450:Sulfones / Q000627:therapeutic use; D014261:Tricuspid Valve / Q000601:surgery*; D014665:Vasodilator Agents / Q000627:therapeutic use
chemical_list: D000935:Antifungal Agents; D010879:Piperazines; D011687:Purines; D013450:Sulfones; D014665:Vasodilator Agents; D009569:Nitric Oxide; D015725:Fluconazole; D000068677:Sildenafil Citrate