title: Pulmonary congenital cystic adenomatoid malformation, type I, presenting as a single cyst of the middle lobe in an adult: case report.
abstract: BACKGROUND
  Congenital cystic adenomatoid malformation (CCAM) of the lung is an uncommon fetal development anomaly of the terminal respiratory structures. The large cyst type usually occurs in stillborn infants or newborn infants with respiratory distress. Cases of CCAM have been previously described in adulthood, more often type I with multiloculated cystic lesions.
  
  
  METHODS
  We report a case of type I CCAM presenting as a single, expansive cystic mass in the middle pulmonary lobe in a 38-year-old man, revealed by persistent cough and haemoptysis. Computed tomographic scan showed a single cyst with air fluid level, occupying the lateral segment of the lobe. When the type I CCAM is a single cyst, other cystic pulmonary lesions must be excluded. The intrapulmonary localization and the absence of cartilage in the cyst wall are conclusive findings of CCAM. The pathogenesis, management and differential diagnosis with other lung malformations are discussed along with a review of the literature.
  
  
  CONCLUSIONS
  The literature data confirm that surgical resection is the treatment of choice in all cases of CCAM and in the cases of cystic pulmonary lesions with uncertain radiological findings, in order to perform a histological examination of the lesion and to prevent infection and the potential neoplastic transformation.
authors.affiliation: Department of Pathology, S. Maria del Carmine Hospital, Rovereto, TN, Italy. luca.morelli@apss.tn.it
authors.forename: Luca
authors.initials: L
authors.lastname: Morelli
authors.forename: Irene
authors.initials: I
authors.lastname: Piscioli
authors.forename: Stefano
authors.initials: S
authors.lastname: Licci
authors.forename: Salvatore
authors.initials: S
authors.lastname: Donato
authors.forename: Alessia
authors.initials: A
authors.lastname: Catalucci
authors.forename: Franca
authors.initials: F
authors.lastname: Del Nonno