title: The long-term outcome of children managed with extracorporeal life support: an institutional experience.
abstract: OBJECTIVE
  To evaluate the long-term functional status and quality of life of infants and children who have received extracorporeal life support (ECLS), and to determine how and when death occurred.
  
  
  METHODS
  Long-term, prospective follow-up study.
  
  
  METHODS
  16-bed paediatric intensive care unit in a university teaching hospital.
  
  
  METHODS
  All children who received ECLS in the period April 1988 to October 2000 in the paediatric ICU at the Royal Children's Hospital, Melbourne, VIC.
  
  
  METHODS
  The records of all 224 children who had received ECLS were reviewed, and functional status and quality of life were assessed through interview with each child's parent or guardian for those who had survived.
  
  
  RESULTS
  Follow-up information was available for 211 children at a median of 7.2 years (range, 3.9 months to 12.6 years) after admission to the paediatric ICU. Sixty-nine children were alive at follow-up, 96% of whom were likely to lead an independent existence. Of the 142 deaths, 123 occurred in the paediatric ICU: 74 were due to elective withdrawal of therapy for poor prognosis, and eight for brain death; 30 were disease-related; seven were ECLSrelated; and four were due to sepsis.
  
  
  CONCLUSIONS
  ECLS is a complex therapy which has been used in Australian children for 18 years; a third of children survived long term, and 96% of these had a favourable outcome.
authors.affiliation: Intensive Care Unit, Royal Children's Hospital, Melbourne, VIC, Australia.
authors.forename: Anna K
authors.initials: AK
authors.lastname: Taylor
authors.forename: Rachel
authors.initials: R
authors.lastname: Cousins
authors.forename: Warwick W
authors.initials: WW
authors.lastname: Butt
mesh_terms: D000203:Activities of Daily Living; D002648:Child; D002675:Child, Preschool; D015199:Extracorporeal Membrane Oxygenation / Q000706:statistics & numerical data*; D005500:Follow-Up Studies; D017052:Hospital Mortality; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D015278:Intensive Care Units, Pediatric / Q000706:statistics & numerical data*; D011788:Quality of Life; D012720:Severity of Illness Index; D011795:Surveys and Questionnaires; D014739:Victoria