Manic symptoms and quality of life in bipolar disorder.
This study evaluates the influence of manic symptoms on quality of life in a sample of adult bipolar disorder (BD) patients. This was a cross-sectional study including 125 BD outpatients from a university-based program. All patients were diagnosed using the Structured Clinical Interview for DSM-IV for BD. Manic symptoms and quality of life were assessed using the Young Mania Rating Scale (YMRS) and the World Health Organization Quality of Life Instrument-Short Version (WHOQOL-BREF), respectively. In the unadjusted analysis using linear regression, the score of manic symptoms was inversely associated with scores of quality of life within the social domain of the WHOQOL. In the adjusted analysis, the score of manic symptoms was inversely associated with the social, physical, and psychological domains of the WHOQOL. In a separate analysis at the YMRS items, items 4 (irritability) and 5 (sleep) were associated with lower quality of life.
Gazalle
Fernando Kratz
FK
Psychiatric Research Unit, Post-Graduate Psychiatry Program, Federal University of Rio Grande do Sul, Porto Alegre, RS, Brazil.
Hallal
Pedro Curi
PC
Andreazza
Ana Cristina
AC
Frey
Benício Noronha
BN
Kauer-Sant'Anna
Márcia
M
Weyne
Fernanda
F
da Costa
Sabrina Corrêa
SC
Santin
Aida
A
Kapczinski
Flávio
F
D000203:Activities of Daily Living / Q000523:psychology; D000223:Adaptation, Psychological; D000328:Adult; D000553:Ambulatory Care; D001294:Attitude to Health; D001714:Bipolar Disorder / Q000175:diagnosis / Q000523:psychology*; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011569:Psychiatric Status Rating Scales; D011788:Quality of Life / Q000523:psychology*; D012919:Social Behavior; D012931:Social Environment