Analysis of intracranial pressure during acute intracranial hypertension using Lempel-Ziv complexity: further evidence.
We analyzed intracranial pressure (ICP) signals during periods of acute intracranial hypertension (ICH) using the Lempel-Ziv (LZ) complexity measure. Our results indicate the LZ complexity of ICP decreases during periods of ICH. The mean LZ complexity before ICH was 0.20+/-0.04, while the mean LZ complexity during ICH was 0.16+/-0.03 (p<0.05). The mean decrease of the LZ complexity values during the ICH episodes was 19.5%. Additionally, we present preliminary evidence suggesting that periods of ICH may be detectable from non-invasive signals coupled with ICP, such as pulse oximetry (SpO2).
Hornero
Roberto
R
Biomedical Engineering Group, E.T.S. Ingenieros de Telecomunicación, University of Valladolid, Camino del Cementerio s/n, 47011, Valladolid, Spain. robhor@tel.uva.es
Aboy
Mateo
M
Abásolo
Daniel
D
D001930:Brain Injuries / Q000503:physiopathology; D019277:Entropy; D006801:Humans; D019586:Intracranial Hypertension / Q000503:physiopathology*; D007427:Intracranial Pressure / Q000502:physiology*; D008959:Models, Neurological; D008991:Monitoring, Physiologic; D010363:Pattern Recognition, Automated / Q000379:methods; D012815:Signal Processing, Computer-Assisted