title: Huge primary myxoma of skull base: a report of an uncommon case.
abstract: We report a 27-year-old male who presented with paroxysmal headache, stuffy nose, epistaxis and impairment of vision in each eye. A huge chondrosarcoma, arising from the skull base with extension into the middle cranial fossa and nasal cavity was suspected. The patient underwent craniotomy and endoscope-assisted transnasal resection and a satisfactory removal was achieved. Postoperative immunohistochemical examination confirmed the diagnosis of myxoma rather than chondrosarcoma. The patient remained neurologically intact except for poor vision in the left eye at six-month follow-up. The relevant literature was reviewed and discussed. The main treatment of myxomas of cranial base is by surgery.
authors.affiliation: Department of Neurosurgery, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
authors.forename: H
authors.initials: H
authors.lastname: Yin
authors.forename: B-W
authors.initials: BW
authors.lastname: Cai
authors.forename: H-M
authors.initials: HM
authors.lastname: An
authors.forename: C
authors.initials: C
authors.lastname: You
mesh_terms: D000328:Adult; D002813:Chondrosarcoma / Q000175:diagnosis; D035301:Cranial Fossa, Middle / Q000473:pathology / Q000503:physiopathology / Q000601:surgery; D003399:Craniotomy; D003937:Diagnosis, Differential; D004724:Endoscopy; D006801:Humans; D008297:Male; D009232:Myxoma / Q000473:pathology* / Q000503:physiopathology / Q000601:surgery; D009296:Nasal Cavity / Q000473:pathology / Q000503:physiopathology / Q000601:surgery; D019635:Neurosurgical Procedures; D009901:Optic Nerve Diseases / Q000209:etiology / Q000473:pathology / Q000503:physiopathology; D009915:Orbit / Q000473:pathology / Q000503:physiopathology; D010256:Paranasal Sinuses / Q000473:pathology / Q000503:physiopathology; D011183:Postoperative Complications / Q000209:etiology / Q000503:physiopathology; D019291:Skull Base / Q000473:pathology* / Q000503:physiopathology / Q000601:surgery; D019292:Skull Base Neoplasms / Q000473:pathology* / Q000503:physiopathology / Q000601:surgery; D016896:Treatment Outcome; D015354:Vision, Low / Q000209:etiology / Q000503:physiopathology