Preliminary analysis of the G178A polymorphism of insulin-like factor 3 in male infertility.
We investigated the association of nonsynonymous insulin-like factor 3 (INSL3) G178A polymorphism with nonobstructive male infertility. The common INSL3 G178A polymorphism was not statistically significantly associated with male infertility (P>.05), even though INSL3 is essential for the occurrence of bilateral cryptorchidism.
Yun
Yeo-Jin
YJ
Functional Genomics Lab, CHA Research Institute, Bundang Campus, College of Medicine, Pochon CHA University, Sungnam City, Kyunggi-Do, Korea.
Lee
Han-Chul
HC
Kim
Jee-Eun
JE
Song
Seung-Hun
SH
Lee
Suman
S
D000483:Alleles; D016022:Case-Control Studies; D004252:DNA Mutational Analysis; D008040:Genetic Linkage; D005820:Genetic Testing; D006801:Humans; D007248:Infertility, Male / Q000235:genetics*; D007328:Insulin / Q000235:genetics*; D008297:Male; D020641:Polymorphism, Single Nucleotide; D011506:Proteins / Q000235:genetics*
D007328:Insulin; C084797:Leydig insulin-like protein; D011506:Proteins