title: Skeletal absorbed fractions for electrons in the adult male: considerations of a revised 50-microm definition of the bone endosteum.
abstract: In 1995, the International Commission on Radiological Protection (ICRP) issued ICRP Publication 70 which provided an extensive update to the physiological and anatomical reference data for the skeleton of adults and children originally issued in ICRP Publication 23. Although ICRP Publication 70 has been a valuable document in the development of reference voxel computational phantoms, additional guidance is needed for dose assessment in the skeletal tissues beyond that given in ICRP Publication 30. In this study, a computed tomography (CT) and micro-CT-based model of the skeletal tissues is presented, which considers (1) a 50-microm depth in marrow for the osteoprogenitor cells, (2) electron escape from trabecular spongiosa to the surrounding cortical bone, (3) cortical bone to trabecular spongiosa cross-fire for electrons and (4) variations in specific absorbed fraction with changes in bone marrow cellularity for electrons. A representative data set is given for electron dosimetry in the craniofacial bones of the adult male.
authors.affiliation: Advanced Laboratory for Radiation Dosimetry Studies (ALRADS), Department of Nuclear and Radiological Engineering, University of Florida, Gainesville, FL 32611-8300, USA. wbolch@ufl.edu
authors.forename: W E
authors.initials: WE
authors.lastname: Bolch
authors.forename: A P
authors.initials: AP
authors.lastname: Shah
authors.forename: C J
authors.initials: CJ
authors.lastname: Watchman
authors.forename: D W
authors.initials: DW
authors.lastname: Jokisch
authors.forename: P W
authors.initials: PW
authors.lastname: Patton
authors.forename: D A
authors.initials: DA
authors.lastname: Rajon
authors.forename: M
authors.initials: M
authors.lastname: Zankl
authors.forename: N
authors.initials: N
authors.lastname: Petoussi-Henss
authors.forename: K F
authors.initials: KF
authors.lastname: Eckerman
mesh_terms: D001681:Biological Assay / Q000379:methods*; D003198:Computer Simulation; D004583:Electrons; D005147:Facial Bones / Q000502:physiology*; D008954:Models, Biological; D011829:Radiation Dosage; D011874:Radiometry / Q000379:methods*; D012062:Relative Biological Effectiveness; D012680:Sensitivity and Specificity; D013045:Species Specificity; D014018:Tissue Distribution