title: Relationship between depression score and acid-base status in Japanese Black calves with diarrhea.
abstract: We evaluated the relationship between depression score and acid-base status in 84 purebred and crossbred Japanese Black calves. The bicarbonate (p<0.001) and base excess concentrations (p<0.001) were significantly and negatively correlated with the depression scores of the calves. The proposed diagnostic cutoff point for a depression score that indicates severe metabolic acidosis (BE < -10 mM) is 6.5 based on analysis of the ROC curve. The sensitivity and specificity were 88.4% and 81.2%, respectively. The depression scoring system is a useful tool for evaluation of the acid-base status of purebred and crossbred Japanese Black calves. In addition, a depression score of 6.5 suggests severe metabolic acidosis and that intravenous infusion of sodium bicarbonate solution is necessary.
authors.affiliation: Veterinary Clinical Center, Hokushin, Agricultural Mutual Aid Association, Kishima, Liyama, Nagano, Japan.
authors.forename: Mitsuhide
authors.initials: M
authors.lastname: Nakagawa
authors.forename: Kazuyuki
authors.initials: K
authors.lastname: Suzuki
authors.forename: Kiyoshi
authors.initials: K
authors.lastname: Taguchi
mesh_terms: D000136:Acid-Base Equilibrium / Q000502:physiology*; D000818:Animals; D001639:Bicarbonates / Q000097:blood; D001784:Blood Gas Analysis / Q000662:veterinary; D002417:Cattle; D002418:Cattle Diseases / Q000503:physiopathology*; D003681:Dehydration / Q000209:etiology / Q000503:physiopathology*; D003967:Diarrhea / Q000150:complications / Q000503:physiopathology / Q000662:veterinary*; D007564:Japan; D012372:ROC Curve; D012018:Reflex / Q000502:physiology
chemical_list: D001639:Bicarbonates