title: Antibacterial activity of red and white wine against oral streptococci.
abstract: Wine contains a number of biologically active compounds with beneficial effects on human health. The antibacterial action of commercial red and white wines against oral streptococci responsible for caries development and against S. pyogenes responsible for pharyngitis was studied. Its postcontact effect against S. mutans was also studied. Both wines displayed activity. The compounds responsible for such activities were succinic, malic, lactic, tartaric, citric, and acetic acid. The synthetic mixtures of the organic acids tested at the concentrations found in wine had greater antibacterial activity than the beverages, indicating that in wine they are inhibited by other components. Wine polyphenols displayed no activity against oral streptococci or S. pyogenes. Findings show that wine is active against oral streptococci and S. pyogenes and suggest that it enhances oral health.
authors.affiliation: Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Pavia, Pavia, Italy.
authors.forename: Maria
authors.initials: M
authors.lastname: Daglia
authors.forename: Adele
authors.initials: A
authors.lastname: Papetti
authors.forename: Pietro
authors.initials: P
authors.lastname: Grisoli
authors.forename: Camilla
authors.initials: C
authors.lastname: Aceti
authors.forename: Cesare
authors.initials: C
authors.lastname: Dacarro
authors.forename: Gabriella
authors.initials: G
authors.lastname: Gazzani
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D002264:Carboxylic Acids / Q000494:pharmacology; D003731:Dental Caries / Q000382:microbiology / Q000517:prevention & control; D009055:Mouth / Q000382:microbiology*; D013291:Streptococcus / Q000187:drug effects*; D014920:Wine / Q000032:analysis*
chemical_list: D000900:Anti-Bacterial Agents; D002264:Carboxylic Acids