Effects of individual components of multiple behavior changes: the PREMIER trial.
OBJECTIVE
To assess contributions of individual lifestyle changes on systolic blood pressure (SBP) changes.


METHODS
We examined associations between lifestyle behavior changes and SBP after 6 and 18 months in 782 PREMIER trial participants.


RESULTS
In multivariate models omitting weight, predicted SBP reductions ranged from (1)/2 to 1(1)/2 mm Hg for reduced urinary sodium, improved fitness, and adherence to the DASH diet (except sodium at 18 months). With weight included, only fitness change additionally predicted SBP at 18 months.


CONCLUSIONS
Several lifestyle behavior changes are important for BP lowering, but are difficult to detect when weight is included in multivariate models.
Obarzanek
Eva
E
National Heart, Lung, and Blood Institute, Bethesda, MD 20892-7936, USA. obarzane@nhlbi.nih.gov
Vollmer
William M
WM
Lin
Pao-Hwa
PH
Cooper
Lawton S
LS
Young
Deborah R
DR
Ard
Jamy D
JD
Stevens
Victor J
VJ
Simons-Morton
Denise G
DG
Svetkey
Laura P
LP
Harsha
David W
DW
Elmer
Patricia J
PJ
Appel
Lawrence J
LJ
D000328:Adult; D000428:Alcohol Drinking / Q000517:prevention & control; D001521:Behavior Therapy; D001794:Blood Pressure; D015992:Body Mass Index; D001835:Body Weight; D003131:Combined Modality Therapy; D018752:Diet, Fat-Restricted; D004039:Diet, Sodium-Restricted; D002149:Energy Intake; D015444:Exercise; D005260:Female; D005500:Follow-Up Studies; D015438:Health Behavior; D006339:Heart Rate; D006801:Humans; D006973:Hypertension / Q000628:therapy*; D008019:Life Style; D008297:Male; D015999:Multivariate Analysis; D010809:Physical Fitness; D012964:Sodium / Q000652:urine; D015431:Weight Loss
D012964:Sodium