Giant sarcoid tumor of the iris and ciliary body.
OBJECTIVE
To report the occurrence of a giant iridociliary sarcoid tumor.


METHODS
The patient was evaluated by medical history, ophthalmoscopic examination (including photography and ultrasonography) as well as systemic, hematologic, and radiographic examinations. Tumor biopsies allowed for cytopathologic, histopathologic, and immunohistochemical analysis.


RESULTS
The 39-year-old black male was found to have a right iris and ciliary body tumor. Ultrasonography revealed a 10 x 12-mm base, 5.6-mm height, low internal reflectivity, and vitreous debris. Radiographic imaging revealed mediastinal and bilateral hilar lymphadenopathy. A purified protein derivative (PPD) and a hematologic survey were negative. Pathology evaluations of the surgical specimens revealed features of non-caseating granulomata consistent with sarcoidosis. A combination of topical and systemic steroid therapy was locally curative.


CONCLUSIONS
We describe a giant iridociliary sarcoid tumor in a patient with no lacrimal gland enlargement, conjunctival nodules, or skin lesions. A biopsy was required to establish the diagnosis.
Finger
Paul T
PT
The New York Eye Cancer Center and the Ocular Tumor and Uveitis Services, The New York Eye and Ear Infirmary, New York City, NY 10065, USA. pfinger@eyecancer.com
Narayana
Kannan
K
Iacob
Codrin E
CE
Samson
C Michael
CM
Latkany
Paul
P
D000328:Adult; D001706:Biopsy; D002924:Ciliary Body; D003937:Diagnosis, Differential; D005500:Follow-Up Studies; D006801:Humans; D015811:Iris Neoplasms / Q000175:diagnosis* / Q000601:surgery; D008297:Male; D013508:Ophthalmologic Surgical Procedures; D012509:Sarcoma / Q000175:diagnosis* / Q000601:surgery; D014604:Uveal Neoplasms / Q000175:diagnosis / Q000601:surgery