title: Do cerebrovascular risk factors confer risk for suicide in later life? A case-control study.
abstract: OBJECTIVE
  Cerebrovascular pathologies have been implicated as a cause of depressive disorders. This study aims to examine the role of cerebrovascular risk factors in late-life suicide.
  
  
  METHODS
  The authors calculated cerebrovascular risk factor (CVRF) score, based on the American Heart Association Criteria, for each case and comparison subject from a psychological autopsy study of suicide among community-dwelling adults over age 50 years.
  
  
  RESULTS
  CVRF scores were significantly higher in suicide cases than community-dwelling comparison subjects after accounting for age, sex, depression diagnosis, and functional status.
  
  
  CONCLUSIONS
  Cerebrovascular disease may predispose to suicide in older adults by a variety of psychopathological means.
authors.affiliation: Department of Psychiatry, The Chinese University of Hong Kong, Hong Kong, China. schan@cuhk.edu.hk
authors.forename: Sandra S
authors.initials: SS
authors.lastname: Chan
authors.forename: Jeffrey M
authors.initials: JM
authors.lastname: Lyness
authors.forename: Yeates
authors.initials: Y
authors.lastname: Conwell
mesh_terms: D000368:Aged; D016022:Case-Control Studies; D002561:Cerebrovascular Disorders / Q000453:epidemiology* / Q000523:psychology*; D006801:Humans; D008875:Middle Aged; D012307:Risk Factors; D013405:Suicide / Q000706:statistics & numerical data*