Reactivity patterns of cytochrome P450 enzymes: multifunctionality of the active species, and the two states-two oxidants conundrum.
Shaik
Sason
S
Department of Organic Chemistry and The Lise Meitner-Minerva Center for Computational Quantum Chemistry, The Hebrew University of Jerusalem, Givat Ram, 91904 Jerusalem, Israel. sason@yfaat.ch.huji.ac.il
Hirao
Hajime
H
Kumar
Devesh
D
D003577:Cytochrome P-450 Enzyme System / Q000737:chemistry* / Q000378:metabolism*; D007501:Iron / Q000737:chemistry / Q000378:metabolism; D008665:Metalloporphyrins / Q000737:chemistry / Q000378:metabolism; D008956:Models, Chemical; D009942:Organometallic Compounds / Q000737:chemistry / Q000378:metabolism; D016877:Oxidants / Q000737:chemistry* / Q000378:metabolism
D008665:Metalloporphyrins; D009942:Organometallic Compounds; D016877:Oxidants; D003577:Cytochrome P-450 Enzyme System; D007501:Iron