[Salivary involvement in IgG4-related multifocal fibrosclerosing disease].
OBJECTIVE
To report a case of IgG4-related multifocal fibrosclerosis, revealed by a multifocal salivary involvement.


METHODS
A 59-year-old man, with chronic pancreatitis, was managed for fibrotic involvement of the 2 submaxillary glands and the 2 parotids. Clinical, radiological, and histologic features were retrospectively studied.


RESULTS
Pathological features of submandibular gland revealed a chronic sclerosing sialadenitis. Retroperitoneal fibrosis in computed tomography and high rate of IgG4 are objectived. The diagnosis of IgG4-related multifocal fibrosclerosis is evoked. The patient's state improved with corticosteroid therapy.


CONCLUSIONS
Salivary involvement in IgG4-related multifocal fibrosclerosis must be recognized in salivary medical pathology.
Montalban
A
A
Service d'ORL et de chirurgie cervicofaciale, hôpital Gabriel-Montpied, CHU de Clermont-Ferrand, rue Montalembert, 63000 Clermont-Ferrand, France.
Vellin
J-F
JF
Andre
M
M
Palat
S
S
Nohra
O
O
Kemeny
J-L
JL
Aumaitre
O
O
Gilain
L
L
D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D006801:Humans; D007074:Immunoglobulin G / Q000276:immunology*; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D010179:Pancreas / Q000000981:diagnostic imaging / Q000473:pathology; D019283:Pancreatitis, Acute Necrotizing / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D012469:Salivary Glands / Q000276:immunology / Q000473:pathology; D012793:Sialadenitis / Q000175:diagnosis* / Q000188:drug therapy / Q000276:immunology*; D014057:Tomography, X-Ray Computed
D000893:Anti-Inflammatory Agents; D007074:Immunoglobulin G