An efficient synthesis of nitroalkenes by alkene cross metathesis: facile access to small ring systems.
A synthesis of highly functionalized nitroalkenes is reported that utilizes a cross metathesis (CM) reaction between simple aliphatic nitro compounds and a range of substituted alkenes. This chemistry offers a simple and attractive route to nitroalkenes that would otherwise be difficult to prepare, and that have a very useful application as precursors to a variety of heterocyclic entities.
Marsh
Graham P
GP
Department of Chemistry, School of Life Sciences, University of Sussex, Falmer, Brighton, United Kingdom.
Parsons
Philip J
PJ
McCarthy
Clive
C
Corniquet
Xavier G
XG
D000475:Alkenes / Q000138:chemical synthesis* / Q000737:chemistry; D003500:Cyclization; D003517:Cyclopentanes / Q000138:chemical synthesis / Q000737:chemistry; D007202:Indicators and Reagents; D007555:Isoxazoles / Q000138:chemical synthesis / Q000737:chemistry; D009574:Nitro Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D010880:Piperidines / Q000138:chemical synthesis
D000475:Alkenes; D003517:Cyclopentanes; D007202:Indicators and Reagents; D007555:Isoxazoles; D009574:Nitro Compounds; D010880:Piperidines; C032727:piperidine