title: Prevalence of nasal colonization with methicillin-resistant Staphylococcus aureus (MRSA) in children a multicenter cross-sectional study.
abstract: In this cross-sectional multicenter study, we determined the rate of nasal carriage of methicillin-resistant Staphylococcus aureus (MRSA) in children admitted to 9 training hospitals in Switzerland during 1 month. From 1337 patients, 1363 nasal swabs were obtained (mean age 6.1 years, median 4.7 years, interquartile range 1.3-10.4 years) and 562 (41.3%) grew S. aureus. Only one isolate was MRSA (0.18%) which encoded mecA and femA genes as well as SCCmec type IV, whereas Panton-Valentine leukocidin (PVL) was absent.
authors.affiliation: University Children's Hospital, Basel, Switzerland. ulrich.heininger@ukbb.ch
authors.forename: Ulrich
authors.initials: U
authors.lastname: Heininger
authors.forename: Florence
authors.initials: F
authors.lastname: Datta
authors.forename: Alain
authors.initials: A
authors.lastname: Gervaix
authors.forename: Urs B
authors.initials: UB
authors.lastname: Schaad
authors.forename: Christoph
authors.initials: C
authors.lastname: Berger
authors.forename: Bernard
authors.initials: B
authors.lastname: Vaudaux
authors.forename: Christoph
authors.initials: C
authors.lastname: Aebi
authors.forename: Michael
authors.initials: M
authors.lastname: Hitzler
authors.forename: Christian
authors.initials: C
authors.lastname: Kind
authors.forename: Hanspeter E
authors.initials: HE
authors.lastname: Gnehm
authors.forename: Reno
authors.initials: R
authors.lastname: Frei
mesh_terms: D000293:Adolescent; D001426:Bacterial Proteins / Q000235:genetics; D001427:Bacterial Toxins / Q000235:genetics; D002353:Carrier State / Q000453:epidemiology* / Q000382:microbiology*; D002648:Child; D002675:Child, Preschool; D003430:Cross-Sectional Studies; D004269:DNA, Bacterial / Q000235:genetics; D005098:Exotoxins / Q000235:genetics; D005260:Female; D006760:Hospitalization; D006784:Hospitals, Teaching; D006801:Humans; D007223:Infant; D007956:Leukocidins / Q000235:genetics; D008297:Male; D016106:Methicillin Resistance; D009296:Nasal Cavity / Q000382:microbiology*; D046915:Penicillin-Binding Proteins; D015995:Prevalence; D013203:Staphylococcal Infections / Q000453:epidemiology* / Q000382:microbiology*; D013211:Staphylococcus aureus / Q000187:drug effects* / Q000302:isolation & purification*; D013557:Switzerland / Q000453:epidemiology
chemical_list: D001426:Bacterial Proteins; D001427:Bacterial Toxins; D004269:DNA, Bacterial; D005098:Exotoxins; C096686:FemA protein, Bacteria; D007956:Leukocidins; C078284:Panton-Valentine leukocidin; D046915:Penicillin-Binding Proteins; C487789:mecA protein, Staphylococcus aureus