[Clinical research of isatis root eyedrops on the acute bacterial conjunctivitis].
OBJECTIVE
To evaluate the efficacy and safety of isatis root eyedrops on the acute bacterial conjunctivitis.


METHODS
A randomized, double-blind and parallel study was conducted on 200 cases. Isatis root eyedrops and Hailun eyedrops (levofloxacin eyedrops), six times each day, were administered in test and control groups respectively. All patients have been observed for 7 days. The clinical effectiveness and reaction to drug after administration were assessed as the observation indexes.


RESULTS
The efficacy rates in test and control group were 90% and 93%, repectively, the difference between the two groups had no statistic significance (P > 0.05). There have been two cases with side effects among the test and control groups respectively.


CONCLUSIONS
Isatis root eyedrops have an excellent efficacy and safety on the acute bacterial conjunctivitis.
Qi
Chao-Xiu
CX
The Ophthalmology Department of the Third Affiliated Hospital, Sun Yat-Sen University, Guangzhou 510630, China.
Wu
Xiao-mei
XM
Wang
Xiao-li
XL
D000293:Adolescent; D000328:Adult; D000368:Aged; D000890:Anti-Infective Agents / Q000627:therapeutic use*; D003234:Conjunctivitis, Bacterial / Q000188:drug therapy*; D004311:Double-Blind Method; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D006801:Humans; D031219:Isatis / Q000737:chemistry*; D064704:Levofloxacin; D008875:Middle Aged; D015242:Ofloxacin / Q000627:therapeutic use; D009883:Ophthalmic Solutions; D008517:Phytotherapy; D018517:Plant Roots / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry; D016896:Treatment Outcome
D000890:Anti-Infective Agents; D004365:Drugs, Chinese Herbal; D009883:Ophthalmic Solutions; D064704:Levofloxacin; D015242:Ofloxacin