title: Ewing's sarcoma of the third metatarsal: a case report and review of the literature.
abstract: We report a rare case of Ewing's sarcoma involving the third metatarsal bone and spreading into adjacent bone in a 23-year-old man, with special emphasis on imaging characteristics. On radiographs the tumor presented as a permeative lytic lesion with aggressive periosteal reaction and cortical destruction. Computed tomography and magnetic resonance imaging delineated the osseous and soft tissue extent of the tumor. A large soft-tissue mass around the involved bone was highly indicative of Ewing's sarcoma. Cortical invasion of the neighboring second metatarsal was seen only on magnetic resonance imaging. Increased up-take of technetium 99m methylene diphosphonate was noticed on bone scintigraphy. An early diagnosis of Ewing's sarcoma, even when it occurs in unusual locations, is necessary for adequate treatment and is of particular importance in terms of prognosis. The optimal imaging modality for the diagnosis of Ewing's sarcoma is magnetic resonance imaging since it allows accurate analysis of the soft-tissue component and visualization of possible local invasion of adjacent structures.
authors.affiliation: University of Zagreb, School of Medicine, Zagreb, Croatia.
authors.forename: Kristina
authors.initials: K
authors.lastname: Potocki
authors.forename: Maja
authors.initials: M
authors.lastname: Prutki
authors.forename: Marko
authors.initials: M
authors.lastname: Kralik
authors.forename: Maja
authors.initials: M
authors.lastname: Hrabak
authors.forename: Ranka Stern
authors.initials: RS
authors.lastname: Padovan
mesh_terms: D000328:Adult; D003952:Diagnostic Imaging / Q000379:methods* / Q000592:standards; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008682:Metatarsal Bones / Q000473:pathology*; D009361:Neoplasm Invasiveness; D011859:Radiography; D012512:Sarcoma, Ewing / Q000175:diagnosis / Q000473:pathology*; D014057:Tomography, X-Ray Computed