Tailored quartz pins for high-density microsensor array fabrication.
We report on a quartz pin that can be interfaced easily to existing pin printers. The new pin surface can be reversibly derivatized using silanization chemistry, allowing one to reliably print a wide variety of liquid solutions. Feature sizes as small as 9 microm can be produced with the new pin, allowing one to readily create microarrays with a feature density approaching 10(6) spots/cm2.
Tehan
Elizabeth C
EC
Department of Chemistry, Natural Sciences Complex, University at Buffalo, The State University of New York, Buffalo, New York 14260-3000, USA.
Higbee
Daniel J
DJ
Wood
Troy D
TD
Bright
Frank V
FV
D017438:Bisphenol A-Glycidyl Methacrylate / Q000737:chemistry; D004867:Equipment Design; D046228:Microarray Analysis / Q000295:instrumentation*; D011327:Printing; D011791:Quartz / Q000737:chemistry*; D012996:Solutions / Q000737:chemistry; D013499:Surface Properties
D012996:Solutions; D011791:Quartz; D017438:Bisphenol A-Glycidyl Methacrylate; C033930:Silar (3M)