title: Absence of endometrium as a cause of primary amenorrhea.
abstract: OBJECTIVE
  To describe congenital endometrial absence.
  
  
  METHODS
  Case report.
  
  
  METHODS
  University hospital.
  
  
  METHODS
  A 32-year-old woman presented with primary amenorrhea and infertility. Hormone analysis, physical and gynecologic examinations, transvaginal ultrasonography, and karyotype analysis were normal.
  
  
  METHODS
  Progesterone challenge test, laparoscopy, hysteroscopy were performed, and hysteroscopic biopsies were obtained from the uterine cavity.
  
  
  METHODS
  Presence of endometrium, menstruation.
  
  
  RESULTS
  The progesterone challenge test was negative. Laparoscopy revealed normal pelvic structures. Evaluation of biopsies from uterine cavity revealed absence of endometrium.
  
  
  CONCLUSIONS
  Endometrial absence is a differential diagnosis for primary amenorrhea; assessment of the uterine cavity and obtaining biopsy samples may help in diagnosis of suspected cases before they undergo assisted reproduction and can avoid unnecessary treatment.
authors.affiliation: Department of Obstetrics and Gynecology, Ankara University Faculty of Medicine, Ankara, Turkey.
authors.forename: Bulent
authors.initials: B
authors.lastname: Berker
authors.forename: Salih
authors.initials: S
authors.lastname: Taşkin
authors.forename: Elif Aylin
authors.initials: EA
authors.lastname: Taşkin
mesh_terms: D000328:Adult; D000568:Amenorrhea / Q000209:etiology* / Q000235:genetics / Q000473:pathology / Q000628:therapy; D003937:Diagnosis, Differential; D003940:Diagnostic Techniques, Endocrine; D004717:Endometrium / Q000002:abnormalities* / Q000473:pathology; D005260:Female; D006801:Humans; D015907:Hysteroscopy; D007247:Infertility, Female / Q000209:etiology* / Q000235:genetics / Q000473:pathology / Q000628:therapy; D007621:Karyotyping; D010535:Laparoscopy; D011374:Progesterone; D014463:Ultrasonography / Q000379:methods; D019564:Unnecessary Procedures; D014591:Uterine Diseases / Q000150:complications / Q000151:congenital / Q000175:diagnosis* / Q000235:genetics / Q000473:pathology
chemical_list: D011374:Progesterone