title: Magnifying chromoscopy, a novel and useful technique for colonoscopy in ulcerative colitis.
abstract: Ulcerative colitis (UC) is a chronic inflammatory bowel disorder characterized by exacerbations and remissions. The degree of inflammation as assessed by conventional colonoscopy is a reliable parameter of disease activity. However, even when conventional colonoscopy suggests remission and normal mucosal findings, microscopic abnormalities may persist, and relapse may occur later. Patients with long-standing, extensive ulcerative colitis have an increased risk of developing colorectal cancer. Ulcerative colitis-associated colorectal cancer is characterized by an early age at onset, poorly differentiated tumor cells, mucinous carcinoma, and multiple lesions. Early detection of dysplasia and colitic cancer is thus a prerequisite for survival. A relatively new method, magnifying chromoscopy, is thought to be useful for the early detection and diagnosis of dysplasia and colitic cancer, as well as the prediction of relapse.
authors.affiliation: Department of Gastroenterology, Nagoya University Graduate School of Medicine, Nagoya, Japan. takafumia-gi@umin.ac.jp
authors.forename: Takafumi
authors.initials: T
authors.lastname: Ando
authors.forename: Hironao
authors.initials: H
authors.lastname: Takahashi
authors.forename: Osamu
authors.initials: O
authors.lastname: Watanabe
authors.forename: Osamu
authors.initials: O
authors.lastname: Maeda
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Ishiguro
authors.forename: Daisuke
authors.initials: D
authors.lastname: Ishikawa
authors.forename: Motofusa
authors.initials: M
authors.lastname: Hasegawa
authors.forename: Naoki
authors.initials: N
authors.lastname: Ohmiya
authors.forename: Yasumasa
authors.initials: Y
authors.lastname: Niwa
authors.forename: Hidemi
authors.initials: H
authors.lastname: Goto
mesh_terms: D003093:Colitis, Ulcerative / Q000473:pathology*; D020685:Colonoscopes; D003113:Colonoscopy / Q000379:methods*; D042241:Early Diagnosis; D006801:Humans; D012008:Recurrence