K+ -dependent Na+/Ca2+ exchangers: key contributors to Ca2+ signaling.
An elevation in cytosolic Ca2+ is a universal signaling mechanism that controls a vast array of physiological processes. K+ -dependent Na+/Ca2+ exchangers are a newly identified family of Ca2+ efflux transporters that play important and diverse roles in cellular Ca2+ homeostasis.
Visser
Frank
F
Department of Biochemistry and Molecular Biology, Libin Cardiovascular Institute of Alberta and the Hotchkiss Brain Institute, University of Calgary, Calgary, Alberta, Canada.
Lytton
Jonathan
J
D000818:Animals; D002118:Calcium / Q000378:metabolism*; D020013:Calcium Signaling / Q000502:physiology*; D006706:Homeostasis / Q000502:physiology; D006801:Humans; D019831:Sodium-Calcium Exchanger / Q000737:chemistry / Q000378:metabolism*
D019831:Sodium-Calcium Exchanger; C074530:potassium-dependent sodium-calcium exchanger; D002118:Calcium