Prevalence of nasal colonization with methicillin-resistant Staphylococcus aureus (MRSA) in children a multicenter cross-sectional study.
In this cross-sectional multicenter study, we determined the rate of nasal carriage of methicillin-resistant Staphylococcus aureus (MRSA) in children admitted to 9 training hospitals in Switzerland during 1 month. From 1337 patients, 1363 nasal swabs were obtained (mean age 6.1 years, median 4.7 years, interquartile range 1.3-10.4 years) and 562 (41.3%) grew S. aureus. Only one isolate was MRSA (0.18%) which encoded mecA and femA genes as well as SCCmec type IV, whereas Panton-Valentine leukocidin (PVL) was absent.
Heininger
Ulrich
U
University Children's Hospital, Basel, Switzerland. ulrich.heininger@ukbb.ch
Datta
Florence
F
Gervaix
Alain
A
Schaad
Urs B
UB
Berger
Christoph
C
Vaudaux
Bernard
B
Aebi
Christoph
C
Hitzler
Michael
M
Kind
Christian
C
Gnehm
Hanspeter E
HE
Frei
Reno
R
D000293:Adolescent; D001426:Bacterial Proteins / Q000235:genetics; D001427:Bacterial Toxins / Q000235:genetics; D002353:Carrier State / Q000453:epidemiology* / Q000382:microbiology*; D002648:Child; D002675:Child, Preschool; D003430:Cross-Sectional Studies; D004269:DNA, Bacterial / Q000235:genetics; D005098:Exotoxins / Q000235:genetics; D005260:Female; D006760:Hospitalization; D006784:Hospitals, Teaching; D006801:Humans; D007223:Infant; D007956:Leukocidins / Q000235:genetics; D008297:Male; D016106:Methicillin Resistance; D009296:Nasal Cavity / Q000382:microbiology*; D046915:Penicillin-Binding Proteins; D015995:Prevalence; D013203:Staphylococcal Infections / Q000453:epidemiology* / Q000382:microbiology*; D013211:Staphylococcus aureus / Q000187:drug effects* / Q000302:isolation & purification*; D013557:Switzerland / Q000453:epidemiology
D001426:Bacterial Proteins; D001427:Bacterial Toxins; D004269:DNA, Bacterial; D005098:Exotoxins; C096686:FemA protein, Bacteria; D007956:Leukocidins; C078284:Panton-Valentine leukocidin; D046915:Penicillin-Binding Proteins; C487789:mecA protein, Staphylococcus aureus