Extremely elevated serum CA-125 level as a result of unruptured unilateral endometrioma: the highest value reported.
OBJECTIVE
To present a case of a unilateral endometrioma with extremely elevated serum CA-125 levels.


METHODS
Case report.


METHODS
University hospital.


METHODS
A 25-year-old woman with left adnexal mass and extremely elevated serum CA-125 level, 7,900 U/mL, underwent laparoscopy. There were unilateral endometrioma and stage IV endometriosis.


METHODS
Laparoscopic excision of the endometrioma, unilateral salpingectomy, adhesiolysis, ablation of endometriotic foci, and partial omentectomy were performed, and histopathologic results confirmed the diagnosis of endometriosis.


METHODS
Extremely elevated serum CA-125 levels and unruptured ovarian endometrioma.


RESULTS
On the second, sixth, and 13th days of the menstrual period, serum CA-125 levels were 7,900 U/mL, 1,577 U/mL, and 627 U/mL, respectively. On the third postoperative day serum CA-125 level was 56 U/mL.


CONCLUSIONS
Ovarian endometrioma and advanced endometriosis may be associated with extremely elevated serum CA-125 levels. For this reason ovarian endometrioma should be considered with respect to differential diagnosis of reproductive-age women presenting with an ovarian mass even if it resembles an ovarian malignancy.
Kahraman
Korhan
K
Department of Obstetrics and Gynecology, Ankara University School of Medicine, Ankara, Turkey. korhankahraman@hotmail.com
Ozguven
Irem
I
Gungor
Mete
M
Atabekoglu
Cem Somer
CS
D000328:Adult; D018394:CA-125 Antigen / Q000097:blood*; D004715:Endometriosis / Q000097:blood* / Q000276:immunology / Q000473:pathology / Q000601:surgery; D005260:Female; D006801:Humans; D008598:Menstruation / Q000097:blood
D018394:CA-125 Antigen