Risk for infection with highly pathogenic influenza A virus (H5N1) in chickens, Hong Kong, 2002.
We used epidemiologic evaluation, molecular epidemiology, and a case-control study to identify possible risk factors for the spread of highly pathogenic avian influenza A virus (subtype H5N1) in chicken farms during the first quarter of 2002 in Hong Kong. Farm profiles, including stock sources, farm management, and biosecurity measures, were collected from 16 case and 46 control chicken farms by using a pretested questionnaire and personal interviews. The risk for influenza A (H5N1) infection was assessed by using adjusted odds ratios based on multivariate logistic regression analysis. Retail marketing of live poultry was implicated as the main source of exposure to infection on chicken farms in Hong Kong during this period. Infection control measures should be reviewed and upgraded as necessary to reduce the spread of influenza A (H5N1) related to live poultry markets, which are commonplace across Asia.
Kung
Nina Y
NY
Massey University, Palmerston North, New Zealand. kungn@agriquality.com
Morris
Roger S
RS
Perkins
Nigel R
NR
Sims
Les D
LD
Ellis
Trevor M
TM
Bissett
Lucy
L
Chow
Mary
M
Shortridge
Ken F
KF
Guan
Yi
Y
Peiris
Malik J S
MJ
D000822:Animal Husbandry; D000818:Animals; D016022:Case-Control Studies; D002645:Chickens; D004196:Disease Outbreaks; D006723:Hong Kong / Q000453:epidemiology; D053124:Influenza A Virus, H5N1 Subtype / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*; D005585:Influenza in Birds / Q000453:epidemiology*; D017720:Molecular Epidemiology; D015999:Multivariate Analysis; D016017:Odds Ratio; D011201:Poultry Diseases / Q000453:epidemiology*; D012367:RNA, Viral / Q000235:genetics; D012044:Regression Analysis; D012307:Risk Factors; D013045:Species Specificity; D011795:Surveys and Questionnaires
D012367:RNA, Viral