title: [Expression of aquaporins 1, 3, 8, 9 mRNA in human fetal membranes].
abstract: OBJECTIVE
  To investigate the expression of aquaporin (AQP)-1, 3, 8, 9 in human fetal membrane and their role in the human amniotic fluid circulation.
  
  
  METHODS
  RT-PCR was employed for detection of the expressions of AQP-1, 3, 8, 9 mRNA in human amnion and chorion from 20 women with normal term pregnancy.
  
  
  RESULTS
  AQP-1, 3, 8, 9 mRNA expression was detected in both human amnion and chorion, and no significant difference was found in their expression levels or between the amnion and chorion (P>0.05).
  
  
  CONCLUSIONS
  AQP-1, 3, 8, 9 can be associated with intramembranous transport and volume regulation of amniotic fluid.
authors.affiliation: Department of Obstetrics and Gynecology, Second Affiliated Hospital of Sun Yat-sen University, Guangzhou 510120, China.
authors.forename: Rui
authors.initials: R
authors.lastname: Zhang
authors.forename: Dong-Zi
authors.initials: DZ
authors.lastname: Yang
authors.forename: Ying-Lin
authors.initials: YL
authors.lastname: Liu
authors.forename: Chen-Yu
authors.initials: CY
authors.lastname: Gou
authors.forename: Jian-Ping
authors.initials: JP
authors.lastname: Zhang
authors.forename: Yun-Hui
authors.initials: YH
authors.lastname: Wang
mesh_terms: D000328:Adult; D000650:Amnion / Q000196:embryology / Q000378:metabolism; D051398:Aquaporin 1 / Q000235:genetics; D051400:Aquaporin 3 / Q000235:genetics; D020346:Aquaporins / Q000235:genetics*; D002823:Chorion / Q000196:embryology / Q000378:metabolism; D004587:Electrophoresis, Agar Gel; D005321:Extraembryonic Membranes / Q000196:embryology / Q000378:metabolism*; D005260:Female; D018507:Gene Expression Regulation, Developmental; D006801:Humans; D011247:Pregnancy; D020133:Reverse Transcriptase Polymerase Chain Reaction
chemical_list: C109669:AQP9 protein, human; D020346:Aquaporins; C108330:aquaporin 8; D051398:Aquaporin 1; D051400:Aquaporin 3