Osteogenesis imperfecta and holoprosencephaly.
A 17-week female fetus had severe osteogenesis imperfecta and gross holoprosencephaly. This unusual combination has not previously been documented. No obvious environmental or genetic determinants were present.
Wainwright
Helen
H
Division of Anatomical Pathology Division of Human Genetics, Faculty of Health Sciences, University of Cape Town, South Africa.
Beighton
Peter
P
D005260:Female; D005313:Fetal Death; D005333:Fetus / Q000000981:diagnostic imaging; D016142:Holoprosencephaly / Q000150:complications*; D006801:Humans; D008297:Male; D010013:Osteogenesis Imperfecta / Q000150:complications*; D011247:Pregnancy; D011859:Radiography