Refractory hiccup: successful treatment with gabapentin.
OBJECTIVE
To report a patient with intractable hiccup which improved with gabapentin.


METHODS
A 69-year-old woman diagnosed with refractory hiccup that started 50 years before improved dramatically after a trial of gabapentin for essential tremor. Gabapentin withdrawal led to reappearance of hiccup, which improved again after its reintroduction.


CONCLUSIONS
Gabapentin should be considered as a possible therapy for refractory hiccup.
Alonso-Navarro
Hortensia
H
Sección de Neurología, Hospital Virgen de la Concha, Zamora, Spain.
Rubio
Lluisa
L
Jiménez-Jiménez
Félix Javier
FJ
D000368:Aged; D000588:Amines / Q000627:therapeutic use*; D000927:Anticonvulsants / Q000627:therapeutic use*; D003509:Cyclohexanecarboxylic Acids / Q000627:therapeutic use*; D005260:Female; D000077206:Gabapentin; D006606:Hiccup / Q000188:drug therapy*; D006801:Humans; D005680:gamma-Aminobutyric Acid / Q000627:therapeutic use*
D000588:Amines; D000927:Anticonvulsants; D003509:Cyclohexanecarboxylic Acids; D005680:gamma-Aminobutyric Acid; D000077206:Gabapentin