Two children with invasive gastrointestinal aspergillosis.
We report two immunocompromised infants aged six and four months with invasive gastrointestinal aspergillosis. Both patients presented with weight loss and diarrhea. The underlying disorders were combined immunodeficiency and transient hypogammaglobulinemia of infancy. The diagnosis of gastrointestinal aspergillosis was established by gastrointestinal endoscopy and histopathological examination of the tissue specimens. Both children responded well to Amphotericin B.
Kayiran
Petek
P
Department of Pediatrics and Department of Pathology, Sisli Etfal Education and Research Hospital, Istanbul, Turkey.
Urganci
Nafiye
N
Cetinkaya
Feyzullah
F
Tanik
Canan
C
D000361:Agammaglobulinemia / Q000150:complications*; D000666:Amphotericin B / Q000627:therapeutic use; D001228:Aspergillosis / Q000175:diagnosis* / Q000276:immunology / Q000382:microbiology; D005767:Gastrointestinal Diseases / Q000175:diagnosis* / Q000276:immunology / Q000382:microbiology; D041981:Gastrointestinal Tract / Q000276:immunology / Q000382:microbiology*; D006801:Humans; D016867:Immunocompromised Host; D007223:Infant; D008297:Male; D012307:Risk Factors
D000666:Amphotericin B