The value of 99mTc-MDP bone scintigraphy in staging primary lymphoma of bone.
OBJECTIVE
To assess the value of (99m)Tc-MDP bone scintigraphy in the staging of primary bone lymphoma.


METHODS
Thirteen staging scintigrams of patients with biopsy proven primary bone lymphoma were reviewed. The number and location of involved sites of disease were documented in each case.


RESULTS
Seven out of 13 scintigrams (54%) demonstrated a single site of bone involvement. Six cases (46%) showed multifocal disease, including clinically silent weight-bearing sites.


CONCLUSIONS
Bone scintigraphy is a valuable tool in the staging of primary bone lymphoma. It detects multifocal involvement which alters prognosis and possibly treatment. Clinically silent involvement of weight-bearing sites may be detected allowing prophylactic treatment if required.
O'Connor
Angus R
AR
Departments of Radiology, Nottingham City Hospital, Hucknall Road, Nottingham, UK. angusoconnor@hotmail.com
Birchall
James D
JD
O'Connor
Simon R
SR
Bessell
Eric
E
D000368:Aged; D000369:Aged, 80 and over; D001859:Bone Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology*; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D008223:Lymphoma / Q000000981:diagnostic imaging* / Q000473:pathology*; D008297:Male; D009367:Neoplasm Staging / Q000379:methods*; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals; D013669:Technetium Tc 99m Medronate
D019275:Radiopharmaceuticals; D013669:Technetium Tc 99m Medronate