title: Pet rodents and fatal lymphocytic choriomeningitis in transplant patients.
abstract: In April 2005, 4 transplant recipients became ill after receiving organs infected with lymphocytic choriomeningitis virus (LCMV); 3 subsequently died. All organs came from a donor who had been exposed to a hamster infected with LCMV. The hamster was traced back through a Rhode Island pet store to a distribution center in Ohio, and more LCMV-infected hamsters were discovered in both. Rodents from the Ohio facility and its parent facility in Arkansas were tested for the same LCMV strain as the 1 involved in the transplant-associated deaths. Phylogenetic analysis of virus sequences linked the rodents from the Ohio facility to the Rhode Island pet store, the index hamster, and the transplant recipients. This report details the animal traceback and the supporting laboratory investigations.
authors.affiliation: Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA. bamman@cdc.gov
authors.forename: Brian R
authors.initials: BR
authors.lastname: Amman
authors.forename: Boris I
authors.initials: BI
authors.lastname: Pavlin
authors.forename: Cesar G
authors.initials: CG
authors.lastname: Albariño
authors.forename: James A
authors.initials: JA
authors.lastname: Comer
authors.forename: Bobbie R
authors.initials: BR
authors.lastname: Erickson
authors.forename: Jennifer B
authors.initials: JB
authors.lastname: Oliver
authors.forename: Tara K
authors.initials: TK
authors.lastname: Sealy
authors.forename: Martin J
authors.initials: MJ
authors.lastname: Vincent
authors.forename: Stuart T
authors.initials: ST
authors.lastname: Nichol
authors.forename: Christopher D
authors.initials: CD
authors.lastname: Paddock
authors.forename: Abbigail J
authors.initials: AJ
authors.lastname: Tumpey
authors.forename: Kent D
authors.initials: KD
authors.lastname: Wagoner
authors.forename: R David
authors.initials: RD
authors.lastname: Glauer
authors.forename: Kathleen A
authors.initials: KA
authors.lastname: Smith
authors.forename: Kim A
authors.initials: KA
authors.lastname: Winpisinger
authors.forename: Melody S
authors.initials: MS
authors.lastname: Parsely
authors.forename: Phil
authors.initials: P
authors.lastname: Wyrick
authors.forename: Christopher H
authors.initials: CH
authors.lastname: Hannafin
authors.forename: Utpala
authors.initials: U
authors.lastname: Bandy
authors.forename: Sherif
authors.initials: S
authors.lastname: Zaki
authors.forename: Pierre E
authors.initials: PE
authors.lastname: Rollin
authors.forename: Thomas G
authors.initials: TG
authors.lastname: Ksiazek
mesh_terms: D000818:Animals; D000829:Animals, Domestic / Q000821:virology*; D016358:Contact Tracing; D006168:Guinea Pigs; D006801:Humans; D016867:Immunocompromised Host; D008216:Lymphocytic Choriomeningitis / Q000635:transmission*; D008217:Lymphocytic choriomeningitis virus / Q000145:classification / Q000235:genetics; D051379:Mice; D010802:Phylogeny; D051381:Rats; D012377:Rodentia / Q000821:virology*; D019737:Transplants / Q000009:adverse effects; D014481:United States / Q000453:epidemiology; D015047:Zoonoses / Q000635:transmission / Q000821:virology