Life-threatening hobbies in the youth? Two autoptic cases suggesting arrhythmogenic right ventricular cardiomyopathy.
Determining the cause for the sudden death in young adults tends to be complex and difficult. Two cases of death of young people were autoptically investigated who died suddenly while carrying out their hobbies (a 22-year-old male musician and a 20-year-old female dancer). In both cases neither the police investigation, the autopsy, nor the toxicological investigations gave any relevant results. However, when investigating the histology fatty and fibrotic tissue in the right ventricle of the myocardium were found, whereas the myocytes proved to be degenerated--typical for arrhythmogenic right ventricular cardiomyopathy (ARVC). It is important to consider the possibility of heart rhythm failure if a clear reason for sudden death in young adults cannot be detected. Heart rhythm failure often involves the genetic background of the case, which suggests that genetic analysis should be carried out as a supportive means of diagnostics.
Wingenfeld
Lisa
L
Institute of Legal Medicine, University Hospital Essen, University of Duisburg-Essen, Hufelandstrasse 55, 45122 Essen, Germany.
Freislederer
Andreas
A
Schulze-Bahr
Eric
E
Paul
Matthias
M
Bajanowski
Thomas
T
D000328:Adult; D019571:Arrhythmogenic Right Ventricular Dysplasia / Q000473:pathology*; D003615:Dancing; D003645:Death, Sudden / Q000209:etiology*; D005260:Female; D005355:Fibrosis / Q000473:pathology; D049429:Forensic Pathology; D006352:Heart Ventricles / Q000473:pathology*; D006801:Humans; D006984:Hypertrophy / Q000473:pathology; D008297:Male; D009146:Music; D009206:Myocardium / Q000473:pathology; D032383:Myocytes, Cardiac / Q000473:pathology