title: Microbial tannases: advances and perspectives.
abstract: In the last years, tannase has been the subject of a lot of studies due to its commercial importance and complexity as catalytic molecule. Tannases are capable of hydrolyzing complex tannins, which represent the main chemical group of natural anti-microbials occurring in the plants. The general outline of this work includes information of the substrates, the enzyme, and the applications. This review considers in its introduction the concepts and history of tannase and explores scientific and technological aspects. The "advances" trace the route from the general, molecular, catalytic, and functional information obtained under close to optimal conditions for microbial production through purification, description of the enzyme properties, and the commercial applications to the "perspectives" including expression studies, regulation, and potential uses; aspects related to the progress in our understanding of tannin biodegradation are also included.
authors.affiliation: Food Research Department, School of Chemistry, Universidad Autónoma de Coahuila, Blvd. Venustiano Carranza and J. Cardenas s/n, Col. Republica Oriente, 25280, Saltillo, Mexico. cag13761@mail.uadec.mx
authors.forename: Cristóbal N
authors.initials: CN
authors.lastname: Aguilar
authors.forename: Raúl
authors.initials: R
authors.lastname: Rodríguez
authors.forename: Gerardo
authors.initials: G
authors.lastname: Gutiérrez-Sánchez
authors.forename: Christopher
authors.initials: C
authors.lastname: Augur
authors.forename: Ernesto
authors.initials: E
authors.lastname: Favela-Torres
authors.forename: Lilia A
authors.initials: LA
authors.lastname: Prado-Barragan
authors.forename: Ascensión
authors.initials: A
authors.lastname: Ramírez-Coronel
authors.forename: Juan C
authors.initials: JC
authors.lastname: Contreras-Esquivel
mesh_terms: D000595:Amino Acid Sequence; D001419:Bacteria / Q000201:enzymology; D001483:Base Sequence; D002265:Carboxylic Ester Hydrolases / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D003358:Cosmetics; D019649:Food Industry; D005658:Fungi / Q000201:enzymology; D005800:Genes, Fungal / Q000235:genetics; D006868:Hydrolysis; D008969:Molecular Sequence Data; D016415:Sequence Alignment; D013379:Substrate Specificity; D013634:Tannins / Q000737:chemistry / Q000378:metabolism
chemical_list: D003358:Cosmetics; D013634:Tannins; D002265:Carboxylic Ester Hydrolases; C022711:tannase