title: Squamous cell carcinoma in situ in a female urethral diverticulum.
abstract: There have been less than 100 reported cases of carcinoma in a female urethral diverticulum, with only 10 of these cases being squamous cell carcinoma (SCC). The course of this disease is frequently aggressive, despite multimodality treatment, and most patients die within 2 to 3 years. To our knowledge, carcinoma in situ of the female urethral diverticulum has not been reported to date, and thus, optimal treatment is not well defined. A 41-year-old woman was found to have SCC in situ without evidence of invasive carcinoma after diverticulectomy. She elected close observation and remains disease-free at 2 years. A brief overview is given of the presentation, management, and outcomes of urethral diverticular carcinoma.
authors.affiliation: Department of Urology, Louisiana State University Health Sciences Center, 1501 Kings Highway, Shreveport, LA 71130, USA.
authors.forename: Diane
authors.initials: D
authors.lastname: Young
authors.forename: Seth
authors.initials: S
authors.lastname: Bilello
authors.forename: Alex
authors.initials: A
authors.lastname: Gomelsky
mesh_terms: D000328:Adult; D002294:Carcinoma, Squamous Cell / Q000473:pathology* / Q000601:surgery; D004240:Diverticulum / Q000473:pathology* / Q000601:surgery; D005260:Female; D006801:Humans; D014523:Urethral Neoplasms / Q000473:pathology* / Q000601:surgery