[The analysis method and progress in the study of codon bias].
Codon bias refers to the nonrandom usage of synonymous codons for encoding amino acids in organisms. As it is related to the carrier molecular of genetic information (DNA) and functional molecular (protein) of life, this phenomenon implicates important biological sense. In this review, we summarize the basic theories and analysis methods about codon bias; and present the softwares and websites which are usually used for codon usage analysis. The related fields about codon bias and the research progress are also introduced.
Wu
Xian-Ming
XM
College of biological science and technology, Shenyang agriculture university, Shenyang 110161, China.
Wu
Song-Feng
SF
Ren
Da-Ming
DM
Zhu
Yun-Ping
YP
He
Fu-Chu
FC
D000596:Amino Acids / Q000235:genetics; D000818:Animals; D015982:Bias; D003062:Codon / Q000235:genetics*; D020224:Expressed Sequence Tags; D005815:Genetic Code / Q000502:physiology*; D006801:Humans; D008957:Models, Genetic; D014176:Protein Biosynthesis / Q000502:physiology; D012106:Research; D012641:Selection, Genetic
D000596:Amino Acids; D003062:Codon