[The clinical application of acellular urinary bladder submucosa to reconstructive the urethral duct of hypospadias patients].
OBJECTIVE
Attended to apply the acellular urinary bladder submucosa in the operation of the urethral duct reconstruction of penile hypospadias.


METHODS
In 2 cases, the urethral ducts were reconstructed by using the acellular urinary bladder submucosa as dorsal half of the urethra, while the preputial island flap as ventral side. In the other patient, the urethral plate was incised, similar to Snodgrass operation, the matrix was fixed to the corpora cavernosa beneath.


RESULTS
Uroflowmetry and the urethroscopy were been performed in the one year follow up. A bell-shaped flow curve was obtained in the patient after urethroplasty using matrix graft combined with a local flap, and no fistula, stricture was found after a year or half a year follow-up.


CONCLUSIONS
The freeze-dried acellular urinary bladder submucosa had three-dimensional network structure, and the acellular urinary bladder submucosa graft combined with preputial flap for hypospadias repair provided satisfactory functional results.
Wu
Yi-Guang
YG
Plastic Surgery Hospital , Chinese Academy of Medical Science, Beijing 100041, China.
Li
Sen-Kai
SK
Wang
Yong-Qian
YQ
Xin
Zhong-Cheng
ZC
Li
Yang-Qun
YQ
Yang
Ming-Yong
MY
Li
Qiang
Q
D002675:Child, Preschool; D005612:Freeze Drying; D006801:Humans; D007021:Hypospadias / Q000601:surgery*; D008297:Male; D009092:Mucous Membrane / Q000637:transplantation*; D014184:Transplantation, Homologous; D001743:Urinary Bladder / Q000637:transplantation*