title: The yield of head CT in syncope: a pilot study.
abstract: Although head CT is often routinely performed in emergency department (ED) patients with syncope, few studies have assessed its value.
  
  
  OBJECTIVE
  To determine the yield of routine head CT in ED patients with syncope and analyse the factors associated with a positive CT.
  
  
  METHODS
  Prospective, observational, cohort study of consecutive patients presenting with syncope to an urban tertiary-care ED (48,000 annual visits).
  
  
  METHODS
  age >or=18 and loss of consciousness (LOC). Exclusion criteria included persistent altered mental status, drug-related or post-trauma LOC, seizure or hypoglycaemia. Primary outcome was abnormal head CT including subarachnoid, subdural or parenchymal haemorrhage, infarction, signs of acute stroke and newly diagnosed brain mass.
  
  
  RESULTS
  Of 293 eligible patients, 113 (39%) underwent head CT and comprise the study cohort. Ninety-five patients (84%) were admitted to the hospital. Five patients, 5% (95% CI=0.8%-8%), had an abnormal head CT: 2 subarachnoid haemorrhage, 2 cerebral haemorrhage and 1 stroke. Post hoc examination of patients with an abnormal head CT revealed focal neurologic findings in 2 and a new headache in 1. The remaining 2 patients had no new neurologic findings but physical findings of trauma (head lacerations with periorbital ecchymoses suggestive of orbital fractures). All patients with positive findings on CT were >65 years of age. Of the 108 remaining patients who had head CT, 45 (32%-51%) had signs or symptoms of neurologic disease including headache, trauma above the clavicles or took coumadin. Limiting head CT to this population would potentially reduce scans by 56% (47%-65%). If age >60 were an additional criteria, scans would be reduced by 24% (16%-32%). Of the patients who did not have head CT, none were found to have new neurologic disease during hospitalisation or 30-day follow-up.
  
  
  CONCLUSIONS
  Our data suggest that the derivation of a prospectively derived decision rule has the potential to decrease the routine use of head CT in patients presenting to the ED with syncope.
authors.affiliation: Department of Emergency Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, WCC2, One Deaconess Road, Boston, MA 02115, USA. sgrossma@caregroup.harvard.edu
authors.forename: S A
authors.initials: SA
authors.lastname: Grossman
authors.forename: C
authors.initials: C
authors.lastname: Fischer
authors.forename: J L
authors.initials: JL
authors.lastname: Bar
authors.forename: L A
authors.initials: LA
authors.lastname: Lipsitz
authors.forename: L
authors.initials: L
authors.lastname: Mottley
authors.forename: K
authors.initials: K
authors.lastname: Sands
authors.forename: S
authors.initials: S
authors.lastname: Thompson
authors.forename: P
authors.initials: P
authors.lastname: Zimetbaum
authors.forename: N I
authors.initials: NI
authors.lastname: Shapiro
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001921:Brain / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D008297:Male; D010865:Pilot Projects; D011446:Prospective Studies; D011996:Records; D013575:Syncope / Q000000981:diagnostic imaging*; D014057:Tomography, X-Ray Computed