Fungal neuroinfections: rare disease but unacceptably high mortality.
Within last 25 years we have observed 20 cases of fungal meningitis and/or cerebral abscesses. Commonest etiologic agens was Candida spp. (C. albicans 9 of 20). Molds were responsible for 4 cases of brain abscess. Mortality was 50% what seems to be very high. Extremely high mortality is caused by delayed onset of therapy, severe underlying disease and multiresistant fungal organisms such as Mucorales, Fusarium solani and Aureobasidium.
Njambi
S
S
Tropical programmes of St. Elizabeth College of Health and Social Sciences in Eldovel, Kenya and Jiima, Ethiopia.
Huttova
M
M
Kovac
M
M
Freybergh
P F
PF
Bauer
F
F
Muli
J M
JM
D000163:Acquired Immunodeficiency Syndrome / Q000150:complications / Q000382:microbiology; D000935:Antifungal Agents / Q000627:therapeutic use; D001922:Brain Abscess / Q000150:complications / Q000188:drug therapy / Q000382:microbiology* / Q000401:mortality; D002177:Candidiasis / Q000188:drug therapy / Q000401:mortality*; D002648:Child; D002675:Child, Preschool; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D016919:Meningitis, Cryptococcal / Q000150:complications / Q000188:drug therapy / Q000401:mortality; D016921:Meningitis, Fungal / Q000150:complications / Q000188:drug therapy / Q000382:microbiology / Q000401:mortality*; D035583:Rare Diseases; D012189:Retrospective Studies
D000935:Antifungal Agents