Transient migratory osteoporosis: rapid response to pamidronate treatment.
Transient migratory osteoporosis is characterized by the acute onset of migratory pain at weight-bearing joints. The diagnosis is based on clinical findings together with characteristic abnormalities on MRI or bone scan. Each attack is generally self-limiting but may take several months to resolve. We describe 2 cases of transient migratory osteoporosis to highlight their rapid response to pamidronate therapy; in addition, 1 of these cases affected the sacrum, a site not reported to be involved in this condition.
Carty
Sara
S
Department of Rheumatology, University Hospital Wales, Cardiff, Wales, United Kingdom. saracarty@hotmail.com
Herdman
Gareth
G
Williams
Frank
F
Srinivasan
Usha
U
D000328:Adult; D000368:Aged; D018771:Arthralgia / Q000188:drug therapy* / Q000209:etiology; D050071:Bone Density Conservation Agents / Q000627:therapeutic use*; D004164:Diphosphonates / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007262:Infusions, Intravenous; D007719:Knee Joint / Q000473:pathology; D008279:Magnetic Resonance Imaging; D008297:Male; D010024:Osteoporosis / Q000150:complications / Q000188:drug therapy*; D000077268:Pamidronate; D012446:Sacroiliac Joint / Q000473:pathology; D016474:Weight-Bearing
D050071:Bone Density Conservation Agents; D004164:Diphosphonates; D000077268:Pamidronate