The relationship between retrobulbar and choroidal hemodynamics in non-neovascular age-related macular degeneration.
To evaluate the relationship between retrobulbar and choroidal hemodynamics in non-neovascular age-related macular degeneration.



Thirteen patients with age-related macular degeneration were assessed by both color Doppler imaging and scanning laser ophthalmoscope indocyanine green (ICG) angiography. Color Doppler imaging was used to measure peak systolic and end diastolic velocity (from which the resistance index, a measure of the resistance to flow downstream, was calculated) in the retrobulbar vessels. Scanning laser ophthalmoscope ICG angiograms were analyzed by area dilution analysis for quantitative choroidal fluorescence intensity assessment. Color Doppler imaging parameters were correlated with scanning laser ophthalmoscope ICG area dilution analysis parameters.



A good correlation was found between the posterior ciliary arteries resistance index and scanning laser ophthalmoscope ICG area dilution analysis fluorescence duration.



Scanning laser ophthalmoscope ICG area dilution analysis "duration" may serve as an alternative to color Doppler imaging in assessing the resistance to blood flow in the posterior ciliary arteries.
Rechtman
Ehud
E
Goldschleger Eye Institute, Tel-Hashomer, Israel.
Harris
Alon
A
Siesky
Brent
B
Kagemann
Larry
L
Danis
Ronald P
RP
Sines
Dan
D
Ciulla
Thomas A
TA
D000368:Aged; D001783:Blood Flow Velocity; D002829:Choroid / Q000098:blood supply*; D019842:Ciliary Arteries / Q000000981:diagnostic imaging / Q000502:physiology*; D004396:Coloring Agents; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D007208:Indocyanine Green; D008268:Macular Degeneration / Q000000981:diagnostic imaging / Q000503:physiopathology*; D008297:Male; D009880:Ophthalmic Artery / Q000000981:diagnostic imaging / Q000502:physiology*; D009887:Ophthalmoscopy; D009915:Orbit / Q000098:blood supply*; D012039:Regional Blood Flow; D012161:Retinal Artery / Q000000981:diagnostic imaging / Q000502:physiology*; D018615:Ultrasonography, Doppler, Color
D004396:Coloring Agents; D007208:Indocyanine Green