title: Controlled formation and mixing of two-dimensional fluids.
abstract: We introduce a novel technique for the controlled spreading and mixing of lipid monolayers from multilamellar precursors on surfaces covered by the hydrophobic epoxy resin SU-8. The lipid spreads as a monolayer as a result of the high surface tension between SU-8 and the aqueous environment. A micropatterned device with SU-8 lanes, injection pads, and mixing regions, surrounded by hydrophilic Au, was constructed to allow handling of lipid films and to achieve their mixing at controlled stoichiometry. Our findings offer a new approach to dynamic surface functionalization and decoration as well as surface-based catalysis and self-assembly.
authors.affiliation: Department of Chemical and Biological Engineering, Chalmers University of Technology, 412 96 Göteborg, Sweden.
authors.forename: Ilja
authors.initials: I
authors.lastname: Czolkos
authors.forename: Yavuz
authors.initials: Y
authors.lastname: Erkan
authors.forename: Paul
authors.initials: P
authors.lastname: Dommersnes
authors.forename: Aldo
authors.initials: A
authors.lastname: Jesorka
authors.forename: Owe
authors.initials: O
authors.lastname: Orwar
mesh_terms: D000327:Adsorption; D004852:Epoxy Compounds; D005229:Fatty Acids, Monounsaturated / Q000737:chemistry* / Q000493:pharmacokinetics; D010936:Plant Extracts / Q000737:chemistry* / Q000493:pharmacokinetics; D011108:Polymers; D000644:Quaternary Ammonium Compounds / Q000737:chemistry* / Q000493:pharmacokinetics; D013025:Glycine max
chemical_list: D004852:Epoxy Compounds; D005229:Fatty Acids, Monounsaturated; D010936:Plant Extracts; D011108:Polymers; D000644:Quaternary Ammonium Compounds; C520895:SU-8 compound; C070046:1,2-dioleoyloxy-3-(trimethylammonium)propane