[Effect of Galla Chinesis on the demineralization of dental root tissue in pH cycling model].
OBJECTIVE
To evaluate the anti-demineralization efficacy of Galla Chinesis in pH cycling model for elucidating the anti-root caries mechanism.


METHODS
Anti-demineralization efficacy evaluation of the natural medicine in the pH-cycling models was used . Sound human root blocks were pH-cycled through the treatment solution, acidic buffer and neutral buffer. The cycling times for demineralization study were 12 times, 2 times per day. The acidic buffers were retained for calcium analysis by atomic adsorption spectroscopy. The sections of blocks were analysed after pH-cycling by CLSM. Treatments were 4 g x L(-1). Galla Chinesis, 1 g x L(-1) NaF solution and distilled water.


RESULTS
Galla Chinesis was found to inhibit the demineralization in the pH cycling model. Although the effect was not as good as fluoride, there was no significant difference between the two groups.


CONCLUSIONS
These data suggest that Galla Chinesis could modulate the mineralisation behaviour of root tissue in a defined chemical circumstance. These findings support the proposition that Galla Chinesis may be a promising anticaries natural medicine in the future.
Zhu
Bing
B
Beijing Stomatological Hospital Capital Medical University, Beijing 100050, China.
Li
Ji-Yao
JY
Zhou
Xue-Dong
XD
D000818:Animals; D002118:Calcium / Q000378:metabolism*; D003481:Cuspid / Q000187:drug effects / Q000473:pathology; D003731:Dental Caries / Q000517:prevention & control; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007313:Insecta / Q000737:chemistry; D008419:Materia Medica / Q000302:isolation & purification / Q000494:pharmacology*; D018613:Microscopy, Confocal; D012969:Sodium Fluoride / Q000494:pharmacology; D017001:Tooth Demineralization / Q000378:metabolism / Q000473:pathology / Q000517:prevention & control*; D014089:Tooth Remineralization; D014092:Tooth Root / Q000187:drug effects* / Q000378:metabolism / Q000473:pathology
D008419:Materia Medica; D012969:Sodium Fluoride; D002118:Calcium