title: Outcome of endoscopic treatment of adult postintubation tracheal stenosis.
abstract: OBJECTIVE
  To assess the results of primary endoscopic treatment of adult postintubation tracheal stenosis, to identify predictors of a successful outcome, and better define the scope and limitations of minimally-invasive surgery for this condition.
  
  
  METHODS
  Sixty-two consecutive patients treated between April 2003 and 2006 with initial endoscopic surgery were prospectively studied. Patient and lesion characteristics, treatment details, complications, decannulation, and open surgery rates were recorded. Actuarial analysis and Cox regression were used to identify predictors of decannulation and freedom from external surgery.
  
  
  RESULTS
  There were 34 male patients and the average age was 45 +/- 16 years. The average stenosis height was 18 mm (range: 5-55 mm), and 82% of lesions were Myer-Cotton grades III or IV. Lesion height and intubation-to-treatment latency independently predicted success of endoscopic surgery. Ninety-six percent of patients with lesions <30 mm in height were treated endoscopically, but the success rate fell to 20% for lesions longer than 30 mm. Patients with recalcitrant lesions underwent airway augmentation (n = 11) or resection (n = 3), with a 79% success rate. All patients were decannulated, but some, predominantly morbidly obese patients, required long-term stents for dynamic airway compromise. Ninety-eight percent of re-interventions occurred within 6 months.
  
  
  CONCLUSIONS
  Minimally invasive treatment is effective in postintubation airway stenosis and obviates the need for open cervicomediastinal surgery in most patients. Patients with old and long lesions are less likely to be cured endoscopically. For most patients in this subgroup, endoscopic surgery makes airway augmentation a viable, less invasive alternative to resection. Patients were unlikely to require further therapy after 6 months of symptom-free follow-up.
authors.affiliation: Department of Otolaryngology, Charing Cross Hospital, London, UK. RN@cantab.net
authors.forename: S A Reza
authors.initials: SA
authors.lastname: Nouraei
authors.forename: Khalid
authors.initials: K
authors.lastname: Ghufoor
authors.forename: Anil
authors.initials: A
authors.lastname: Patel
authors.forename: Tina
authors.initials: T
authors.lastname: Ferguson
authors.forename: David J
authors.initials: DJ
authors.lastname: Howard
authors.forename: Guri S
authors.initials: GS
authors.lastname: Sandhu
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000402:Airway Obstruction / Q000453:epidemiology; D004724:Endoscopy / Q000379:methods; D006801:Humans; D007442:Intubation, Intratracheal; D007828:Laryngoscopy; D008297:Male; D008875:Middle Aged; D019060:Minimally Invasive Surgical Procedures / Q000379:methods; D009765:Obesity / Q000453:epidemiology; D011183:Postoperative Complications; D012086:Reoperation / Q000706:statistics & numerical data; D013997:Time Factors; D014135:Tracheal Stenosis / Q000453:epidemiology / Q000209:etiology* / Q000601:surgery*; D016896:Treatment Outcome