title: A simple method for detection of major phenotypic abnormalities in myelodysplastic syndromes: expression of CD56 in CMML.
abstract: Using a very simple flow cytometry protocol, we found that CD36 and CD117 on granulocytes and CD56 on monocytes were the major bone marrow phenotypic aberrations in patients with myelodysplasia, including CMML. CD56 on monocytes was associated with CMML. Importantly, phenotypic aberrations were lost on blood cells, except for CD56.
authors.forename: Charlotte
authors.initials: C
authors.lastname: Lacronique-Gazaille
authors.forename: Marie-Pierre
authors.initials: MP
authors.lastname: Chaury
authors.forename: Alexandre
authors.initials: A
authors.lastname: Le Guyader
authors.forename: Jean-Luc
authors.initials: JL
authors.lastname: Faucher
authors.forename: Dominique
authors.initials: D
authors.lastname: Bordessoule
authors.forename: Jean
authors.initials: J
authors.lastname: Feuillard
mesh_terms: D019002:CD56 Antigen / Q000032:analysis*; D005434:Flow Cytometry / Q000379:methods; D006801:Humans; D016130:Immunophenotyping / Q000379:methods; D015477:Leukemia, Myelomonocytic, Chronic / Q000175:diagnosis*; D008722:Methods; D009000:Monocytes / Q000737:chemistry / Q000276:immunology; D009190:Myelodysplastic Syndromes / Q000175:diagnosis
chemical_list: D019002:CD56 Antigen