Cytoprotective effect of Panax ginseng on gallic acid-induced toxicity in TM3 mouse Leydig cells.
Our previous study had demonstrated cytotoxicity of gallic acid on testicular cells with increasing the intracellular production of hydrogen peroxide. In the present study, the Panax ginseng root aqueous extract showed the cytoprotective effect on gallic acid-induced toxicity in TM3 mouse Leydig cells with decreasing the intracellular production of hydrogen peroxide.
Park
Wansu H
WH
College of Oriental Medicine, Kyungwon University, Seongnam 461-701, South Korea. hangl98@naver.com
Chang
Mun Seog
MS
Yang
Woong Mo
WM
Bae
Hyunsu
H
Kim
Nam Il
NI
Park
Seong Kyu
SK
D000818:Animals; D002478:Cells, Cultured; D004305:Dose-Response Relationship, Drug; D005707:Gallic Acid; D006861:Hydrogen Peroxide / Q000378:metabolism; D007985:Leydig Cells / Q000187:drug effects / Q000378:metabolism; D008297:Male; D051379:Mice; D005894:Panax; D008517:Phytotherapy; D010936:Plant Extracts / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D018517:Plant Roots; D020011:Protective Agents / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use
D010936:Plant Extracts; D020011:Protective Agents; D005707:Gallic Acid; D006861:Hydrogen Peroxide