title: [Neumopathies in patients with primary immunodeficiencies in treatment with intravenous gammaglobulin].
abstract: BACKGROUND
  The primary immunodeficiency diseases cause a deficit in the production of antibodies. The chronic sinopulmonary disease is common and their clinic symptoms are diverse (pneumonia, bronchiectasis).
  
  
  OBJECTIVE
  To know the frequency and type of pulmonary abnormalities in patients with primary immunodeficiency in treatment with intravenous immunoglobulin.
  
  
  METHODS
  24 files of patients with primary immunodeficiency were selected. Age, sex, primary immunodeficiency type, time of immunoglobulin treatment, chest X-ray finding, pulmonary computed tomography of high resolution (HRCT) and pulmonary function tests were registered. Measures of central tendency were calculated.
  
  
  RESULTS
  There was no predominance of gender; the average age was 14 years old. The common variable immunodeficiency and the Bruton's hypogammaglobulinemia represented 91% of the patients. The X-ray of thorax was abnormal in 33%, although there were not bronchiectasis. The high-resolution computed tomography scan (HRCT) was abnormal in 67%, and 75% had bronchiectasis.
  
  
  CONCLUSIONS
  The pulmonary complications are common despite therapy with intravenous immunoglobulin. The HRCT is better than X-ray in these patients.
authors.affiliation: Servicio de alergia e inmunologia clinica, Hospital de Especialidades. dmogica@aol.com
authors.forename: María Dolores
authors.initials: MD
authors.lastname: Mogica Martínez
authors.forename: Sergio
authors.initials: S
authors.lastname: García Lara
authors.forename: Rosalia
authors.initials: R
authors.lastname: Silva Vera
authors.forename: Beatriz
authors.initials: B
authors.lastname: Montaño Velázquez
authors.forename: Aarón
authors.initials: A
authors.lastname: Cruz Mérida
authors.forename: Julio
authors.initials: J
authors.lastname: Santibáñez Bustamante
authors.forename: Juan Manuel
authors.initials: JM
authors.lastname: Moreno Martínez
mesh_terms: D000293:Adolescent; D000328:Adult; D000361:Agammaglobulinemia / Q000150:complications / Q000628:therapy; D001987:Bronchiectasis / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000276:immunology / Q000503:physiopathology; D002648:Child; D002675:Child, Preschool; D017074:Common Variable Immunodeficiency / Q000150:complications / Q000628:therapy; D004198:Disease Susceptibility; D005260:Female; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use*; D007153:Immunologic Deficiency Syndromes / Q000150:complications* / Q000628:therapy; D008171:Lung Diseases / Q000000981:diagnostic imaging / Q000453:epidemiology* / Q000276:immunology / Q000503:physiopathology / Q000517:prevention & control; D008297:Male; D015995:Prevalence; D012129:Respiratory Function Tests; D014057:Tomography, X-Ray Computed; D053632:X-Linked Combined Immunodeficiency Diseases / Q000150:complications / Q000628:therapy
chemical_list: D016756:Immunoglobulins, Intravenous