title: Refractory hiccup: successful treatment with gabapentin.
abstract: OBJECTIVE
  To report a patient with intractable hiccup which improved with gabapentin.
  
  
  METHODS
  A 69-year-old woman diagnosed with refractory hiccup that started 50 years before improved dramatically after a trial of gabapentin for essential tremor. Gabapentin withdrawal led to reappearance of hiccup, which improved again after its reintroduction.
  
  
  CONCLUSIONS
  Gabapentin should be considered as a possible therapy for refractory hiccup.
authors.affiliation: Sección de Neurología, Hospital Virgen de la Concha, Zamora, Spain.
authors.forename: Hortensia
authors.initials: H
authors.lastname: Alonso-Navarro
authors.forename: Lluisa
authors.initials: L
authors.lastname: Rubio
authors.forename: Félix Javier
authors.initials: FJ
authors.lastname: Jiménez-Jiménez
mesh_terms: D000368:Aged; D000588:Amines / Q000627:therapeutic use*; D000927:Anticonvulsants / Q000627:therapeutic use*; D003509:Cyclohexanecarboxylic Acids / Q000627:therapeutic use*; D005260:Female; D000077206:Gabapentin; D006606:Hiccup / Q000188:drug therapy*; D006801:Humans; D005680:gamma-Aminobutyric Acid / Q000627:therapeutic use*
chemical_list: D000588:Amines; D000927:Anticonvulsants; D003509:Cyclohexanecarboxylic Acids; D005680:gamma-Aminobutyric Acid; D000077206:Gabapentin