gem-Difluoro-carbasugars, the cases of mannopyranose and galactopyranose.
5a-Difluoro-5a-carbamannopyranose (gem-difluoro-carbamannopyranose) and 5a-difluoro-5a-carbagalactopyranose (gem-difluoro-carbagalactopyranose), close congeners of their respective natural sugars, in which the endocyclic oxygen atom has been replaced by a gem-difluoromethylene group, were synthesized from D-mannose and D-galactose, using a rearrangement strategy.
Sardinha
João
J
Université Pierre et Marie Curie-Paris 6, Institut de Chimie Moléculaire (FR 2769), ENS, UMR CNRS 8642, 75005 Paris, France.
Guieu
Samuel
S
Deleuze
Aurélie
A
Fernández-Alonso
M Carmen
MC
Rauter
Amelia Pilar
AP
Sinaÿ
Pierre
P
Marrot
Jérôme
J
Jiménez-Barbero
Jesús
J
Sollogoub
Matthieu
M
D002236:Carbohydrate Conformation; D005461:Fluorine / Q000737:chemistry*; D005690:Galactose / Q000031:analogs & derivatives / Q000737:chemistry*; D007202:Indicators and Reagents; D008358:Mannose / Q000031:analogs & derivatives / Q000737:chemistry*; D008958:Models, Molecular
D007202:Indicators and Reagents; D005461:Fluorine; D008358:Mannose; D005690:Galactose