Successfully treated acute lymphoblastic leukemia associated with craniopharyngioma.
The authors report a 2-year-old boy with acute lymphoblastic leukemia (ALL) associated with craniopharyngioma. To our knowledge, this is the first such report. Magnetic resonance imaging showed a suprasellar tumor, an apparent cystic lesion, whereas cerebral computed tomography confirmed that the tumor exhibited calcification. Without surgical intervention for the suprasellar tumor, we initiated chemotherapy for ALL. After 1 year of chemotherapy, complete remission was achieved, and partial resection and radiation therapy were performed on the suprasellar tumor. At 4 years after completing leukemia chemotherapy, the patient remains in complete ALL remission and has had no recurrence of craniopharyngioma.
Kurosawa
Hidemitsu
H
Department of Pediatrics, Dokkyo Medical University, Tochigi, Japan. hidekuro@dokkyomed.ac.jp
Matsunaga
Takayuki
T
Shimura
Naoto
N
Nakajima
Daisuke
D
Hagisawa
Susumu
S
Fukushima
Keitaro
K
Sugita
Kenichi
K
Phyo
Kim
K
Arisaka
Osamu
O
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001491:Basophils / Q000473:pathology; D001854:Bone Marrow Cells / Q000473:pathology; D002675:Child, Preschool; D003397:Craniopharyngioma / Q000150:complications / Q000188:drug therapy*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D010911:Pituitary Neoplasms / Q000150:complications / Q000188:drug therapy*; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000188:drug therapy* / Q000473:pathology