title: Neovascularization associated with large retinal pigment epithelial detachment in elderly Korean patients: subdivision according to indocyanine green angiographic features.
abstract: OBJECTIVE
  In Korean patients, to subdivide the neovascular forms of age-related macular degeneration (AMD) associated with large retinal pigment epithelial detachment (PED), according to the indocyanine green angiographic features.
  
  
  METHODS
  Indocyanine green angiograms (ICGA) of 67 elderly patients (72 eyes) who presented with a PED of at least 1 disc diameter were evaluated retrospectively.
  
  
  RESULTS
  Polypoidal choroidal vasculopathy (PCV) and typical choroidal neovascularization (CNV)-associated PEDs were identified in 18 eyes (25%) and 19 eyes (26%), respectively. In ten eyes (13.9%), the exact type of neovascularization, whether PCV or CNV, could not be determined. Pure serous PEDs were identified in seven eyes (10%). The remaining 18 eyes (25%) were classified as having retinal angiomatous proliferation (RAP)-associated PED based upon the angiographic findings of vascular connections between the retinal vasculature and the neovascular complex.
  
  
  CONCLUSIONS
  Three subset groups of PCV, CNV, and RAP were present with similar frequency in neovascularized AMD with a large PED in these Korean patients. In particular, RAP, previously thought to be rare in Asian patients, was found to be present with considerable frequency.
authors.affiliation: Department of Ophthalmology, Kangnam St. Mary's Hospital, Catholic University of Korea, Seoul, Korea. wklee@catholic.ac.kr
authors.forename: Won Ki
authors.initials: WK
authors.lastname: Lee
authors.forename: Young Hoon
authors.initials: YH
authors.lastname: Park
authors.forename: Phil Young
authors.initials: PY
authors.lastname: Lee
mesh_terms: D000368:Aged; D020256:Choroidal Neovascularization / Q000453:epidemiology / Q000209:etiology* / Q000473:pathology; D004396:Coloring Agents; D003937:Diagnosis, Differential; D005260:Female; D005451:Fluorescein Angiography; D005500:Follow-Up Studies; D005654:Fundus Oculi; D006801:Humans; D015994:Incidence; D007208:Indocyanine Green; D007723:Korea / Q000453:epidemiology; D008297:Male; D010857:Pigment Epithelium of Eye / Q000473:pathology*; D012163:Retinal Detachment / Q000150:complications* / Q000453:epidemiology / Q000473:pathology; D012189:Retrospective Studies; D012720:Severity of Illness Index
chemical_list: D004396:Coloring Agents; D007208:Indocyanine Green