Post-varicella myasthenia gravis.
Myasthenia gravis is an autoimmune disease of neuromuscular junctions. We report a three-year-old boy with post-varicella myasthenia gravis. This patient, to the best of our knowledge, is the youngest in age and second reported case of the condition. The patient presented with drooping of both eyelids which increased as the day progressed, two weeks after varicella infection. Repetitive nerve stimulation tests showed decremental response in action potential, and the child responded dramatically to test doses of neostigmine. A diagnosis of post-varicella myasthenia gravis was made and the patient was started on oral pyridostigmine. He is doing well at follow-up and there is no recurrence of symptoms to date.
Saha
A
A
Department of Paediatrics, Mahatma Gandhi Institute of Medical Sciences, Sevagram, Wardha, Maharashtra, India.
Batra
P
P
Vilhekar
K Y
KY
Chaturvedi
P
P
D002644:Chickenpox / Q000150:complications*; D002675:Child, Preschool; D002800:Cholinesterase Inhibitors / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D009157:Myasthenia Gravis / Q000188:drug therapy / Q000821:virology*; D009388:Neostigmine / Q000627:therapeutic use*; D011729:Pyridostigmine Bromide / Q000627:therapeutic use
D002800:Cholinesterase Inhibitors; D009388:Neostigmine; D011729:Pyridostigmine Bromide