title: Bleomycin induced hyperpigmentation with yolk sac tumor.
abstract: Hyperpigmentation is one of the cutaneous side effects of chemotherapautic agents, but it is usually accepted as a cosmetic problem. We report a child with yolk sac tumor who developed localized pigmentation after the first course of chemotherapy regimen that included cisplatin, etoposide and bleomycin. The hyperpigmentation was diffuse scattered, flagellate like and linear streaking which was thought to be mainly related to the skin toxicity of bleomycin.
authors.affiliation: Department of Pediatric Oncology, Faculty of Medicine, Trabzon, Turkey.
authors.forename: Nilgun
authors.initials: N
authors.lastname: Yaris
authors.forename: Murat
authors.initials: M
authors.lastname: Cakir
authors.forename: Mukaddes
authors.initials: M
authors.lastname: Kalyoncu
authors.forename: Aysenur
authors.initials: A
authors.lastname: Okten
mesh_terms: D000903:Antibiotics, Antineoplastic / Q000009:adverse effects*; D001761:Bleomycin / Q000009:adverse effects*; D002675:Child, Preschool; D018240:Endodermal Sinus Tumor / Q000188:drug therapy*; D005260:Female; D006801:Humans; D017495:Hyperpigmentation / Q000139:chemically induced*; D013997:Time Factors
chemical_list: D000903:Antibiotics, Antineoplastic; D001761:Bleomycin