title: A case of clear renal cell cancer associated to meningioma and verrucous carcinoma of frontal region in an old patient.
abstract: Here we report the concomitant development in an 82 year-old patient of three different neoplasms with different histology, degree of differentiation and clinical aggressiveness. In fact, the patient presented a verrucous carcinoma with unusual location at her head frontal region and a concomitant calcified meningioma of the frontal region of the brain. At the moment of the examination also a clear renal cell carcinoma, that was the cause of patient decease, was discovered. At our knowledge, this is the first case of concomitant presentation of these three tumours. Even if the present case was not correlated with any hereditary feature the presence of a genetic predisposition common to all the three tumours can not be excluded, but the casual co-existence of different both genetic and environmental factors can be also suggested.
authors.affiliation: Internal Medicine Unit, S. Giovanni di Dio Hospital, ASL NA3, Frattaminore, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Vetrano
authors.forename: R
authors.initials: R
authors.lastname: Addeo
authors.forename: I
authors.initials: I
authors.lastname: Russo
authors.forename: G
authors.initials: G
authors.lastname: Meo
authors.forename: G
authors.initials: G
authors.lastname: De Rosa
authors.forename: F
authors.initials: F
authors.lastname: D'Anna
authors.forename: M
authors.initials: M
authors.lastname: Caraglia
mesh_terms: D000369:Aged, 80 and over; D002114:Calcinosis / Q000473:pathology*; D002292:Carcinoma, Renal Cell / Q000473:pathology*; D018289:Carcinoma, Verrucous / Q000473:pathology*; D002454:Cell Differentiation; D017809:Fatal Outcome; D005260:Female; D006258:Head and Neck Neoplasms / Q000473:pathology*; D006801:Humans; D007680:Kidney Neoplasms / Q000473:pathology*; D008577:Meningeal Neoplasms / Q000473:pathology*; D008579:Meningioma / Q000473:pathology*; D009361:Neoplasm Invasiveness; D009378:Neoplasms, Multiple Primary / Q000473:pathology*; D014057:Tomography, X-Ray Computed