The effects of fine-needle biopsy on thyroid hormone levels.
OBJECTIVE
Our study aim was to investigate the effects of fine-needle biopsy used for thyroid nodules on serum thyroid hormone levels.


METHODS
A total of 25 patients who had solid nodules of the thyroid gland and normal thyroid hormone levels underwent diagnostic fine-needle biopsy for a nodule of the thyroid gland.


METHODS
Venous blood samples were drawn from the cases for measurement of serum total T(3) and T(4), free T(3) and T(4), thyroid-stimulating hormone, and thyroglobulin levels before, immediately after, and 30 minutes after the initial biopsy.


RESULTS
Total T(3) and thyroglobulin levels were found to be significantly higher immediately and 30 minutes following fine-needle aspiration biopsy, compared to the baseline levels (P<0.05).


CONCLUSIONS
Preliminary data suggest that thyroid hormone levels show a mean increase of about 20% immediately after fine-needle aspiration.


CONCLUSIONS
The implication of this finding on patient care should be determined on an individual basis.
Alpay
H Cengiz
HC
Firat University Medical Faculty, Otorhinolaryngology Department, Elaziğ, Turkey. hayrettincengizalpay@yahoo.com
Kalidag
Turgut
T
Keles
Erol
E
Kaygusuz
Irfan
I
Yalcin
Sinasi
S
Kapusuz
Zeliha
Z
D000328:Adult; D000368:Aged; D044963:Biopsy, Fine-Needle; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012016:Reference Values; D013954:Thyroglobulin / Q000097:blood; D013961:Thyroid Gland / Q000473:pathology; D013963:Thyroid Hormones / Q000097:blood*; D016606:Thyroid Nodule / Q000473:pathology*; D013972:Thyrotropin / Q000097:blood; D013974:Thyroxine / Q000097:blood; D014284:Triiodothyronine / Q000097:blood
D013963:Thyroid Hormones; D014284:Triiodothyronine; D013972:Thyrotropin; D013954:Thyroglobulin; D013974:Thyroxine