Effects of breast milk and milk formula diets on synthesized speech sound-induced event-related potentials in 3- and 6-month-old infants.
Effects of breast milk and milk formula supplemented with docosahexaenoic acid and arachidonic acid on speech processing were investigated by recording event-related potentials (ERPs) to synthesized /pa/ and /ba/ (oddball paradigm, 80%:20%) at 3 and 6 months of age. Behavioral assessment was also obtained. A major positive component (P200) was elicited by both types of sounds. It had a maximal scalp distribution in the fronto-central areas in both groups of infants. The mean latencies did not differ between the groups or between the stimulus types. However, the latencies decreased across age in both groups. The mean P200 amplitude in the formula-fed infants was lower than that in the breast-fed infants, but the difference was not significant. The between-stimulus differences in frontal P200 amplitudes were positively correlated with the behavioral scores of Bayley Index of Infant Development. These data suggest that the processing of the present speech stimuli is not affected by the investigated diets in the early infancy.
Jing
Hongkui
H
Arkansas Children's Nutrition Center, Department of Neurology, University of Arkansas for Medical Sciences, Little Rock, AR 72202, USA. JingHongkui@uams.edu
Pivik
R T
RT
Dykman
Roscoe A
RA
Gilchrist
Janet M
JM
Badger
Thomas M
TM
D000367:Age Factors; D000704:Analysis of Variance; D001931:Brain Mapping; D001942:Breast Feeding; D002657:Child Development; D004569:Electroencephalography / Q000379:methods; D005072:Evoked Potentials, Auditory / Q000502:physiology*; D005260:Female; D007839:Functional Laterality; D006801:Humans; D007223:Infant; D041943:Infant Formula / Q000008:administration & dosage*; D007227:Infant Nutritional Physiological Phenomena; D008297:Male; D008895:Milk, Human; D010700:Phonetics; D011930:Reaction Time