title: [Frequency, etiology, and outcomes of acute renal failure (data of Kaunas University of Medicine Hospital in 1995-2006)].
abstract: The aim of this study was to determine the frequency, etiology, and outcomes of acute renal failure. We retrospectively collected data on all patients (n=1653) who received renal replacement therapy for acute renal failure at the Kaunas University of Medicine Hospital during 1995-2006. The number of patients with acute renal failure increased nine times during the 11-year period. The mean age of patients was 59.76+/-17.52 years and increased from 44.97+/-17.1 years in 1995 to 62.84+/-16.49 years in 2006. The most common causes of acute renal failure were renal (n=646, 39%), prerenal (n=380, 23%), and obstructive (n=145, 9%). The renal replacement therapy was discontinued because of recovery of renal function in 49.9% of cases. The overall hospital mortality rate was 45.1%. Renal function did not recover in 6.7% of patients. The mortality rate over the 11-year period varied from 37.8 to 57.5%. The highest mortality rate was in the neurosurgical (62.3%) and cardiac surgical (61.8%) intensive care units. High mortality rate (more than 50%) was in the groups of patients with acute renal failure that was caused by hepatorenal syndrome, shock, sepsis, and reduced cardiac output.
authors.affiliation: Department of Nephrology, Kaunas University of Medicine, Kaunas, Lithuania. i.skarupskiene@mikrovisata.net
authors.forename: Inga
authors.initials: I
authors.lastname: Skarupskiene
authors.forename: Vytautas
authors.initials: V
authors.lastname: Kuzminskis
authors.forename: Edita
authors.initials: E
authors.lastname: Ziginskiene
mesh_terms: D058186:Acute Kidney Injury / Q000453:epidemiology / Q000209:etiology / Q000401:mortality / Q000628:therapy; D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D002303:Cardiac Output, Low; D002648:Child; D002675:Child, Preschool; D003627:Data Interpretation, Statistical; D005260:Female; D006530:Hepatorenal Syndrome / Q000150:complications; D017052:Hospital Mortality; D006801:Humans; D007223:Infant; D007362:Intensive Care Units; D008097:Lithuania / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D017582:Renal Replacement Therapy; D012189:Retrospective Studies; D018805:Sepsis / Q000150:complications; D012737:Sex Factors; D012769:Shock / Q000150:complications; D016896:Treatment Outcome