Progressive perianeurysmal edema induced after endovascular coil embolization. Report of three cases and review of the literature.
The authors report three cases of progressive vasogenic brain edema surrounding a cerebral aneurysm after endovascular coil embolization. In all three cases embolization was incomplete due to the aneurysms' large sizes and wide necks. Follow-up magnetic resonance imaging revealed de novo vasogenic brain edema surrounding the aneurysms 3 to 6 months after the initial treatment. The edema progressed in parallel with regrowth of the aneurysms. All three aneurysms were deep in the brain parenchyma and showed intramural enhancement, suggesting hemorrhage or inflammation. Each patient underwent a second embolization for the aneurysm regrowth, which resulted in improvement of the edema. Based on the findings in these cases and review of the literature, it is suggested that incomplete occlusion of larger aneurysms that are deep within the brain may lead to a disorganized intraluminal thrombosis, aneurysm pulsing, and intramural hemorrhage or inflammation, all of which are associated with brain edema following aneurysm recanalization and regrowth. It should be kept in mind that incomplete embolization of larger aneurysms may cause such malignant change and that this complication may occur after endovascular treatment.
Horie
Nobutaka
N
Department of Neurosurgery, Nagasaki University School of Medicine, Nagasaki, Japan. nhorienagasaki@yahoo.co.jp
Kitagawa
Naoki
N
Morikawa
Minoru
M
Tsutsumi
Keisuke
K
Kaminogo
Makio
M
Nagata
Izumi
I
D000368:Aged; D015901:Angiography, Digital Subtraction; D001929:Brain Edema / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D002340:Carotid Artery Diseases / Q000175:diagnosis / Q000628:therapy*; D002343:Carotid Artery, Internal; D002533:Cerebral Angiography; D004621:Embolization, Therapeutic / Q000009:adverse effects*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D002532:Intracranial Aneurysm / Q000175:diagnosis / Q000628:therapy*; D018810:Magnetic Resonance Angiography; D008297:Male; D012008:Recurrence; D019233:Retreatment