title: Review of non-FDA-approved fillers.
abstract: The number of commercially available injectable soft tissue fillers has increased dramatically worldwide over the past decade. In the United States, a variety of temporary non-collagen-based fillers have been approved. However, no permanent soft tissue injectable fillers are currently approved by the US Food and Drug Administration. This article discusses some of the more popular soft tissue fillers, such as Restylane Fine Line, Restylane SQ, Perlane, Artecoll, Dermalive, Dermadeep, Bioalcamid, Bioplastique, Evolution, Outline, Argiform, and Aquamid, which are all available outside of the United States.
authors.affiliation: Department of Otolaryngology-Head & Neck Surgery, University of Toronto, Toronto, Ontario, Canada. ellis2106@gmail.com
authors.forename: David A F
authors.initials: DA
authors.lastname: Ellis
authors.forename: Lorne
authors.initials: L
authors.lastname: Segall
mesh_terms: D006801:Humans; D006820:Hyaluronic Acid / Q000031:analogs & derivatives* / Q000627:therapeutic use*; D007267:Injections; D015595:Skin Aging; D013518:Surgery, Plastic / Q000379:methods*; D014481:United States; D014486:United States Food and Drug Administration / Q000331:legislation & jurisprudence*
chemical_list: D006820:Hyaluronic Acid