title: Sympathetic hyperactivity--a hidden enemy in chronic kidney disease patients.
abstract: Chronic kidney disease is often characterized by the presence of sympathetic hyperactivity. The aim of this brief review is to summarize available knowledge on the pathogenesis of sympathetic hyperactivity and to discuss its clinical relevance, the consequences of this knowledge for the choice of treatment, and the yet unresolved issues.
authors.affiliation: Department of Nephrology, University Medical Center, Utrecht, Netherlands. P.J.Blankestijn@umcutrecht.nl
authors.forename: Peter J
authors.initials: PJ
authors.lastname: Blankestijn
mesh_terms: D000818:Animals; D006801:Humans; D006977:Hypertension, Renal / Q000209:etiology / Q000503:physiopathology / Q000628:therapy; D007676:Kidney Failure, Chronic / Q000503:physiopathology* / Q000628:therapy; D006435:Renal Dialysis; D013564:Sympathetic Nervous System / Q000503:physiopathology*