title: Nosocomial meningitis in neonates caused by Streptococcus agalactiae.
abstract: Streptococcus agalactiae is a rare cause of neonatal meningitis in the era of peripartum prophylaxis with prophylaxis with ampicillin in colonized/infected mothers. However 5 cases of meningitis among 171 cases of pediatric nosocomial meningitis database within last 15 years occurred. All 5 children were neonates (one VLBW and early gestation newborn), 2 after neurosurgery. All 5 cases were successfully cured with a combination of cefotaxim (or ceftazidim) plus aminoglycosides, in one case also with addition of vancomycin or ampicillin. However 3 of 5 cured patients had neurologic sequellae, two of them reversible hydrocephalus and in speech retardation.
authors.affiliation: John Paul School of Missiology and Tropical Health, Bratislava, Slovakia.
authors.forename: B
authors.initials: B
authors.lastname: Rudinsky
authors.forename: A
authors.initials: A
authors.lastname: Ondrusova
authors.forename: F
authors.initials: F
authors.lastname: Bauer
authors.forename: J
authors.initials: J
authors.lastname: Benca
authors.forename: M
authors.initials: M
authors.lastname: Huttova
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D003428:Cross Infection / Q000188:drug therapy / Q000209:etiology / Q000382:microbiology*; D006801:Humans; D006849:Hydrocephalus / Q000209:etiology; D007231:Infant, Newborn; D007805:Language Development Disorders / Q000209:etiology; D016920:Meningitis, Bacterial / Q000188:drug therapy / Q000209:etiology / Q000382:microbiology*; D035583:Rare Diseases; D012189:Retrospective Studies; D013290:Streptococcal Infections / Q000150:complications* / Q000188:drug therapy; D013292:Streptococcus agalactiae / Q000472:pathogenicity*
chemical_list: D000900:Anti-Bacterial Agents