title: Post automatic implantable cardioverter defibrillator implant therapies: drugs and ablative techniques.
abstract: The aim of this article is to report the evidences about the use of drugs and ablation after implantation of a cardioverter defibrillator. Drugs can be utilized to prevent appropriate and inappropriate shocks, can influence positively or negatively defibrillation threshold, can be useful for the treatment of electrical storm. Ablation can be performed for direct cure of coexisting atrial and ventricular tachyarrhythmias or for AV node modulation. In particular, previous data demonstrate that rescue ventricular tachycardia ablation of drug-refractory electrical storm is possible by a substrate-orientated ablation approach even in patients with complex chronic infarction and various ventricular tachycardias. At the end of this article it is described how remote monitoring, a new very promising technical improvement, can be utilized for deciding, almost in real time, the use of both these therapies or for controlling their efficacy.
authors.affiliation: Department of Heart and Vessels, University of Florence, Florence, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Colella
authors.forename: P
authors.initials: P
authors.lastname: Pieragnoli
authors.forename: G
authors.initials: G
authors.lastname: Ricciardi
authors.forename: M
authors.initials: M
authors.lastname: Giaccardi
authors.forename: L
authors.initials: L
authors.lastname: Padeletti
authors.forename: A
authors.initials: A
authors.lastname: Michelucci
mesh_terms: D000889:Anti-Arrhythmia Agents / Q000627:therapeutic use*; D001145:Arrhythmias, Cardiac / Q000188:drug therapy / Q000601:surgery / Q000628:therapy*; D001281:Atrial Fibrillation / Q000628:therapy; D017115:Catheter Ablation; D017147:Defibrillators, Implantable; D006801:Humans; D017180:Tachycardia, Ventricular / Q000628:therapy; D016896:Treatment Outcome; D014693:Ventricular Fibrillation / Q000628:therapy
chemical_list: D000889:Anti-Arrhythmia Agents