title: The effectiveness of vitamin "E" in the treatment of oral mucositis in children receiving chemotherapy.
abstract: The aim of this study was to study the effect of vitamin "E" in the treatment of oral mucositis. 80 patients with oral mucositis were randomly distributed into 2 groups: group A, topically applied vitamin "E" and group B, vitamin "E" was given systemically. The 2 groups were evaluated for 5 days. Results showed that in group A grades of oral mucositis improved significantly, while in group B no significant improvement was noticed. It is concluded that topical application of 100 mg vitamin "E" twice daily is an effective measure for the treatment of chemotherapy-induced oral mucositis.
authors.affiliation: Pediatric and Community Dentistry Department, Faculty of Dentistry, University of Alexandria, El-Ibrahimia, Alexandria, Egypt. ahussini@hotmail.com
authors.forename: Azza A
authors.initials: AA
authors.lastname: El-Housseiny
authors.forename: Susan M
authors.initials: SM
authors.lastname: Saleh
authors.forename: Ashraf A
authors.initials: AA
authors.lastname: El-Masry
authors.forename: Amany A
authors.initials: AA
authors.lastname: Allam
mesh_terms: D000284:Administration, Oral; D000287:Administration, Topical; D000970:Antineoplastic Agents / Q000009:adverse effects*; D000975:Antioxidants / Q000008:administration & dosage*; D002648:Child; D006801:Humans; D052016:Mucositis / Q000139:chemically induced / Q000188:drug therapy*; D013280:Stomatitis / Q000139:chemically induced / Q000188:drug therapy*; D014810:Vitamin E / Q000008:administration & dosage*; D014815:Vitamins / Q000008:administration & dosage*
chemical_list: D000970:Antineoplastic Agents; D000975:Antioxidants; D014815:Vitamins; D014810:Vitamin E