Invasive nosocomial aspergillosis associated with heart failure and complete heart block following recovery from dengue shock syndrome.
OBJECTIVE
To report a case of invasive aspergillosis, associated with complete heart block and heart failure, in an immunocompetent child recovering from dengue shock syndrome.


METHODS
Case report and literature review.


METHODS
Pediatric intensive care unit in a tertiary care center.


RESULTS
A 9-yr-old boy was admitted to our pediatric intensive care unit with dengue shock syndrome, for which he was successfully managed. During the recovery phase, the child developed recurrence of fever and signs of congestive heart failure. Thereafter, he developed complete heart block and died. Myocardial biopsy revealed myocarditis and invading fungal elements with branching septate hyphae suggestive of Aspergillus. A renal biopsy specimen also showed glomerular invasion with Aspergillus and patchy necrosis. This suggested the diagnosis of invasive aspergillosis.


CONCLUSIONS
This case highlights an unusual manifestation of invasive aspergillosis in a critically ill immunocompetent child.
Kohli
Utkarsh
U
Department of Pediatrics, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India.
Sahu
Jitendra
J
Lodha
Rakesh
R
Agarwal
Nidhi
N
Ray
Ruma
R
D001228:Aspergillosis / Q000150:complications*; D002648:Child; D003428:Cross Infection / Q000150:complications*; D017809:Fatal Outcome; D006327:Heart Block / Q000209:etiology*; D006333:Heart Failure / Q000209:etiology*; D006801:Humans; D008297:Male; D019595:Severe Dengue / Q000150:complications