Lupus anticoagulant and off-pump coronary bypass: dilemma of anticoagulation.
Confronted with a persistently elevated activated partial thromboplastin time due to circulating lupus anticoagulant in a patient undergoing emergency off-pump coronary artery bypass surgery, the dilemma of providing adequate anticoagulation for a short cardiac surgical procedure is highlighted.
Maddali
Madan M
MM
Department of Anesthesia, Royal Hospital, PB No: 1331, PC: 111, Seeb, Muscat, Sultanate of Oman. madan@omantel.net.om
Albahrani
Maher J
MJ
D000328:Adult; D000925:Anticoagulants / Q000009:adverse effects / Q000627:therapeutic use*; D016736:Antiphospholipid Syndrome / Q000097:blood / Q000150:complications* / Q000188:drug therapy; D000990:Antithrombin III / Q000032:analysis; D001777:Blood Coagulation / Q000187:drug effects*; D047549:Coronary Artery Bypass, Off-Pump; D023921:Coronary Stenosis / Q000097:blood / Q000150:complications / Q000188:drug therapy / Q000601:surgery*; D004632:Emergency Medical Services; D006493:Heparin / Q000009:adverse effects / Q000627:therapeutic use*; D006801:Humans; D016682:Lupus Coagulation Inhibitor / Q000097:blood*; D008297:Male; D010314:Partial Thromboplastin Time; D018579:Patient Selection; D016896:Treatment Outcome
D000925:Anticoagulants; D016682:Lupus Coagulation Inhibitor; D000990:Antithrombin III; D006493:Heparin