Absence of endometrium as a cause of primary amenorrhea.
OBJECTIVE
To describe congenital endometrial absence.


METHODS
Case report.


METHODS
University hospital.


METHODS
A 32-year-old woman presented with primary amenorrhea and infertility. Hormone analysis, physical and gynecologic examinations, transvaginal ultrasonography, and karyotype analysis were normal.


METHODS
Progesterone challenge test, laparoscopy, hysteroscopy were performed, and hysteroscopic biopsies were obtained from the uterine cavity.


METHODS
Presence of endometrium, menstruation.


RESULTS
The progesterone challenge test was negative. Laparoscopy revealed normal pelvic structures. Evaluation of biopsies from uterine cavity revealed absence of endometrium.


CONCLUSIONS
Endometrial absence is a differential diagnosis for primary amenorrhea; assessment of the uterine cavity and obtaining biopsy samples may help in diagnosis of suspected cases before they undergo assisted reproduction and can avoid unnecessary treatment.
Berker
Bulent
B
Department of Obstetrics and Gynecology, Ankara University Faculty of Medicine, Ankara, Turkey.
Taşkin
Salih
S
Taşkin
Elif Aylin
EA
D000328:Adult; D000568:Amenorrhea / Q000209:etiology* / Q000235:genetics / Q000473:pathology / Q000628:therapy; D003937:Diagnosis, Differential; D003940:Diagnostic Techniques, Endocrine; D004717:Endometrium / Q000002:abnormalities* / Q000473:pathology; D005260:Female; D006801:Humans; D015907:Hysteroscopy; D007247:Infertility, Female / Q000209:etiology* / Q000235:genetics / Q000473:pathology / Q000628:therapy; D007621:Karyotyping; D010535:Laparoscopy; D011374:Progesterone; D014463:Ultrasonography / Q000379:methods; D019564:Unnecessary Procedures; D014591:Uterine Diseases / Q000150:complications / Q000151:congenital / Q000175:diagnosis* / Q000235:genetics / Q000473:pathology
D011374:Progesterone