title: Long-term support with milrinone prior to cardiac transplantation in a neonate with left ventricular noncompaction cardiomyopathy.
abstract: A 2-week-old female infant presented with acute decompensated left ventricular failure. Echocardiography diagnosed left ventricular noncompaction cardiomyopathy with dilated phenotype and a left ventricular shortening fraction <10%. The infant was mechanically ventilated for 2 weeks and then successfully extubated. She was maintained on intravenous milrinone for 6 months until she underwent successful orthotopic heart transplantation. Young children can be supported with inotropes for prolonged periods while awaiting heart transplantation.
authors.affiliation: Department of Paediatric Cardiology, Heart Failure Unit, Our Lady's Hospital for Sick Children, Crumlin, Dublin 12, Ireland. cmcmahon992004@yahoo.com
authors.forename: C J
authors.initials: CJ
authors.lastname: McMahon
authors.forename: H
authors.initials: H
authors.lastname: Murchan
authors.forename: T
authors.initials: T
authors.lastname: Prendiville
authors.forename: M
authors.initials: M
authors.lastname: Burch
mesh_terms: D009202:Cardiomyopathies / Q000188:drug therapy* / Q000601:surgery; D002316:Cardiotonic Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D003131:Combined Modality Therapy; D005260:Female; D016027:Heart Transplantation; D006801:Humans; D007231:Infant, Newborn; D007262:Infusions, Intravenous; D020105:Milrinone / Q000008:administration & dosage / Q000627:therapeutic use*; D012121:Respiration, Artificial; D018487:Ventricular Dysfunction, Left / Q000188:drug therapy / Q000209:etiology
chemical_list: D002316:Cardiotonic Agents; D020105:Milrinone