title: Ageing and vascular adrenoceptor desensitization: too little, too late?
authors.affiliation: Dept of Integrative Physiology, University of Colorado at Boulder, Boulder, CO 80309-0354 USA. donatoa@colorado.edu
authors.forename: Anthony J
authors.initials: AJ
authors.lastname: Donato
mesh_terms: D058646:Adrenergic alpha-1 Receptor Agonists; D058647:Adrenergic alpha-2 Receptor Agonists; D000316:Adrenergic alpha-Agonists / Q000494:pharmacology; D000328:Adult; D000368:Aged; D000375:Aging / Q000378:metabolism / Q000502:physiology*; D001783:Blood Flow Velocity / Q000187:drug effects; D020927:Dexmedetomidine / Q000494:pharmacology; D005263:Femoral Artery / Q000187:drug effects / Q000294:innervation / Q000378:metabolism*; D006801:Humans; D007866:Leg / Q000098:blood supply*; D008297:Male; D008875:Middle Aged; D009638:Norepinephrine / Q000378:metabolism; D010656:Phenylephrine / Q000494:pharmacology; D018340:Receptors, Adrenergic, alpha-1 / Q000378:metabolism*; D018341:Receptors, Adrenergic, alpha-2 / Q000378:metabolism*; D012016:Reference Values; D013564:Sympathetic Nervous System / Q000187:drug effects / Q000378:metabolism*; D014439:Tyramine / Q000494:pharmacology; D014661:Vasoconstriction / Q000187:drug effects; D014662:Vasoconstrictor Agents / Q000494:pharmacology
chemical_list: D058646:Adrenergic alpha-1 Receptor Agonists; D058647:Adrenergic alpha-2 Receptor Agonists; D000316:Adrenergic alpha-Agonists; D018340:Receptors, Adrenergic, alpha-1; D018341:Receptors, Adrenergic, alpha-2; D014662:Vasoconstrictor Agents; D010656:Phenylephrine; D020927:Dexmedetomidine; D009638:Norepinephrine; D014439:Tyramine