Hypoplasminogenemia with ligneous periodontitis: a failed local therapeutic approach.
BACKGROUND
Hypoplasminogenemia is a rare condition that is associated with ligneous conjunctivitis, a form of chronic conjunctivitis characterized by firm, fibrin-rich, pseudomembranous lesions on the tarsal conjunctivae and oral lesions. Pseudomembranes may develop on the gingivae, and there may be periodontal involvement.


METHODS
Several therapeutic approaches have been developed to treat such patients, but they have had limited effect. We used gingivectomies, topical heparin, and corticosteroids to treat periodontal lesions in an 18-year-old girl.


RESULTS
This approach had no benefit.


CONCLUSIONS
The question remains about how best to manage patients with hypoplasminogenemia.
Kurtulus
Idil
I
Department of Periodontology, Faculty of Dentistry, Istanbul University, Istanbul, Turkey. idil_kurtulus@yahoo.com
Gokbuget
Aslan
A
Efeoglu
Ahmet
A
Cintan
Serdar
S
Tefs
Katrin
K
Schuster
Volker
V
Scully
Crispian
C
D000293:Adolescent; D000305:Adrenal Cortex Hormones / Q000008:administration & dosage; D005260:Female; D005343:Fibrinolytic Agents / Q000008:administration & dosage; D005881:Gingiva / Q000473:pathology / Q000601:surgery; D019214:Gingival Overgrowth / Q000188:drug therapy / Q000601:surgery*; D005890:Gingivectomy / Q000379:methods*; D006402:Hematologic Diseases / Q000188:drug therapy / Q000235:genetics / Q000601:surgery*; D006493:Heparin / Q000008:administration & dosage; D006801:Humans; D010518:Periodontitis; D010958:Plasminogen / Q000172:deficiency*; D012008:Recurrence; D017211:Treatment Failure
D000305:Adrenal Cortex Hormones; D005343:Fibrinolytic Agents; D010958:Plasminogen; D006493:Heparin