title: Quantification of 1,3-beta-D-glucan levels in children: preliminary data for diagnostic use of the beta-glucan assay in a pediatric setting.
abstract: 1,3-Beta-D-Glucan serum levels have demonstrated good diagnostic sensitivity and specificity for the diagnosis of candidiasis in adult patients, but normal levels for children have not been established. We found higher 1,3-beta-D-glucan levels in children than those previously reported in adults.
authors.affiliation: Department of Pediatrics, Division of Pediatric Infectious Diseases, Duke University Medical Center, Durham, North Carolina 27710, USA.
authors.forename: P Brian
authors.initials: PB
authors.lastname: Smith
authors.forename: Daniel K
authors.initials: DK
authors.lastname: Benjamin
authors.forename: Barbara D
authors.initials: BD
authors.lastname: Alexander
authors.forename: Melissa D
authors.initials: MD
authors.lastname: Johnson
authors.forename: Malcolm A
authors.initials: MA
authors.lastname: Finkelman
authors.forename: William J
authors.initials: WJ
authors.lastname: Steinbach
mesh_terms: D000293:Adolescent; D000367:Age Factors; D015415:Biomarkers / Q000097:blood*; D002177:Candidiasis / Q000097:blood* / Q000175:diagnosis*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008828:Microbiological Techniques; D012680:Sensitivity and Specificity; D047071:beta-Glucans / Q000097:blood*
chemical_list: D015415:Biomarkers; D047071:beta-Glucans; C033363:beta-1,3-glucan