title: Nail psoriasis improvement in a patient treated with fumaric acid esters.
abstract: Nail psoriasis is common in adult psoriatic patients and it causes serious psychological and physical distress. Topical treatments such as corticosteroids, calcipotriol, retinoids, and 5-fluorouracil have limited efficacy and are not without side effects. Relative effective systemic treatments are ciclosporin, methotrexate and acitretin, all of which have a serious toxicity potential. Biologics in the treatment of nail psoriasis have been the subject of recent research, but their cost-effectiveness is questionable. We present a case of psoriatic nail disease which improved greatly on treatment with fumaric acid esters (FAE).
authors.affiliation: Department of Dermatology, University Hospitals of Coventry and Warwickshire NHS Trust, Coventry, UK. christinavlachou@hotmail.com
authors.forename: Christina
authors.initials: C
authors.lastname: Vlachou
authors.forename: John
authors.initials: J
authors.lastname: Berth-Jones
mesh_terms: D000328:Adult; D003879:Dermatologic Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D005650:Fumarates / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D009260:Nail Diseases / Q000188:drug therapy* / Q000473:pathology; D011565:Psoriasis / Q000188:drug therapy* / Q000473:pathology
chemical_list: D003879:Dermatologic Agents; D005650:Fumarates