title: Giant sarcoid tumor of the iris and ciliary body.
abstract: OBJECTIVE
  To report the occurrence of a giant iridociliary sarcoid tumor.
  
  
  METHODS
  The patient was evaluated by medical history, ophthalmoscopic examination (including photography and ultrasonography) as well as systemic, hematologic, and radiographic examinations. Tumor biopsies allowed for cytopathologic, histopathologic, and immunohistochemical analysis.
  
  
  RESULTS
  The 39-year-old black male was found to have a right iris and ciliary body tumor. Ultrasonography revealed a 10 x 12-mm base, 5.6-mm height, low internal reflectivity, and vitreous debris. Radiographic imaging revealed mediastinal and bilateral hilar lymphadenopathy. A purified protein derivative (PPD) and a hematologic survey were negative. Pathology evaluations of the surgical specimens revealed features of non-caseating granulomata consistent with sarcoidosis. A combination of topical and systemic steroid therapy was locally curative.
  
  
  CONCLUSIONS
  We describe a giant iridociliary sarcoid tumor in a patient with no lacrimal gland enlargement, conjunctival nodules, or skin lesions. A biopsy was required to establish the diagnosis.
authors.affiliation: The New York Eye Cancer Center and the Ocular Tumor and Uveitis Services, The New York Eye and Ear Infirmary, New York City, NY 10065, USA. pfinger@eyecancer.com
authors.forename: Paul T
authors.initials: PT
authors.lastname: Finger
authors.forename: Kannan
authors.initials: K
authors.lastname: Narayana
authors.forename: Codrin E
authors.initials: CE
authors.lastname: Iacob
authors.forename: C Michael
authors.initials: CM
authors.lastname: Samson
authors.forename: Paul
authors.initials: P
authors.lastname: Latkany
mesh_terms: D000328:Adult; D001706:Biopsy; D002924:Ciliary Body; D003937:Diagnosis, Differential; D005500:Follow-Up Studies; D006801:Humans; D015811:Iris Neoplasms / Q000175:diagnosis* / Q000601:surgery; D008297:Male; D013508:Ophthalmologic Surgical Procedures; D012509:Sarcoma / Q000175:diagnosis* / Q000601:surgery; D014604:Uveal Neoplasms / Q000175:diagnosis / Q000601:surgery