Inherited renal acidoses.
Inherited acidosis may result from a primary renal defect in acid-base handling, emphasizing the central role of the kidney in control of body pH; as a secondary phenomenon resulting from abnormal renal electrolyte handling; or from excess production of acid elsewhere in the body. Here, we review our current understanding of the inherited renal acidoses at a genetic and molecular level.
Fry
Andrew C
AC
Department of Medical Genetics and Division of Renal Medicine, University of Cambridge, Cambridge Institute for Medical Research, UK.
Karet
Fiona E
FE
D000137:Acid-Base Imbalance / Q000235:genetics* / Q000378:metabolism*; D000141:Acidosis, Renal Tubular / Q000235:genetics* / Q000378:metabolism*; D000818:Animals; D006801:Humans; D007684:Kidney Tubules / Q000378:metabolism*