Oxygen as a neonatal health hazard: call for détente in clinical practice.
Education in oxygenation and in how oxygen is given to newborns needs to increase. Treatment with oxygen should no longer be considered proverbial and customary, regardless of our 'past experience' or consensus recommendations in clinical guidelines, since oxygen may lead to acute or chronic health effects.


CONCLUSIONS
Inappropriate oxygen use is a neonatal health hazard associated with aging, DNA damage and cancer, retinopathy of prematurity, injury to the developing brain, infection and others. Neonatal exposure to pure O2, even if brief, or to pulse oximetry >95% when breathing supplemental O2 must be avoided as much as possible.
Sola
Augusto
A
Mid Atlantic Neonatology Associates and Morristown Memorial Hospital, Morristown, NJ, USA. augustosolaneo@gmail.com
Rogido
Marta R
MR
Deulofeut
Richard
R
D000375:Aging; D000818:Animals; D001921:Brain / Q000187:drug effects / Q000254:growth & development; D001997:Bronchopulmonary Dysplasia / Q000139:chemically induced; D004249:DNA Damage; D005260:Female; D006454:Hemoglobins / Q000378:metabolism; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D008297:Male; D018384:Oxidative Stress; D010100:Oxygen / Q000009:adverse effects* / Q000378:metabolism; D010101:Oxygen Consumption / Q000502:physiology; D010102:Oxygen Inhalation Therapy / Q000009:adverse effects*; D012151:Resuscitation / Q000379:methods; D012178:Retinopathy of Prematurity / Q000139:chemically induced; D018805:Sepsis / Q000150:complications / Q000378:metabolism; D012737:Sex Factors
D006454:Hemoglobins; D010100:Oxygen