Treatment of gingival overgrowth in a child with Bardet-Biedl syndrome.
BACKGROUND
Bardet-Biedl syndrome (BBS) is a rare, heterogeneous, autosomal recessive condition, primarily characterized by polydactyly, obesity, mental retardation, hypogonadism, retinopathy, and renal failure. Dental anomalies, regarded as secondary manifestations, include hypodontia, microdontia, short roots, and deep palate. Few reports in the literature have described the oral manifestations of BBS. This article reports a case of BBS in a boy who presented some typical oral manifestations added to a generalized gingival overgrowth, an anomaly that had not been reported previously in patients with this syndrome.


METHODS
A 12-year-old white male presented with a diagnosis of BBS and chief complaint of gingival enlargement in the anterior segment of both arcades. The treatment plan included surgical removal of the overgrown gingiva followed by orthodontic therapy. The excised tissues were submitted to histologic analysis.


RESULTS
There was no sign of recurrence 1 year after gingivectomy. Histopathology revealed a dense connective tissue with a mild inflammatory infiltrate, irregularly arranged fiber bundles, and epithelial acanthosis, which is characteristic of gingival overgrowth.


CONCLUSIONS
The gingival overgrowth was treated successfully by gingivectomy. The periodontal surgery minimized the functional, social, and emotional consequences of the oral manifestation associated with the syndrome.
Drugowick
Rayen Millanao
RM
Department of Pediatric Dentistry and Orthodontics, School of Dentistry, Federal University of Rio de Janeiro, RJ, Brazil.
Da Rós Gonçalves
Lorena
L
Barrôso
Aurea Simone
AS
Feres-Filho
Eduardo Jorge
EJ
Maia
Lucianne Cople
LC
D020788:Bardet-Biedl Syndrome / Q000150:complications*; D002648:Child; D003241:Consanguinity; D017742:Dental Care for Chronically Ill / Q000379:methods*; D005881:Gingiva / Q000473:pathology; D019214:Gingival Overgrowth / Q000209:etiology / Q000523:psychology / Q000601:surgery*; D005890:Gingivectomy / Q000379:methods*; D006801:Humans; D008297:Male