Acute insomnia following surgery of the ventralis intermedius nucleus of the thalamus for tremor.
Stereotactic surgery with lesioning or deep brain stimulation directed to the ventralis intermedius nucleus of the thalamus is a well-recognized treatment for medically intractable tremor. A patient developed the rare complication of severe insomnia, easy awakening, and lack of slow-wave sleep after thalamotomy/deep brain stimulation implantation. This complication underscores the role of thalamic regulation on initiation and maintenance of sleep.
Quigg
Mark
M
Department of Neurology, University of Virginia, Charlottesville, VA 22908, USA. quigg@virginia.edu
Frysinger
Robert C
RC
Harrison
Madaline
M
Elias
W Jeffrey
WJ
D000208:Acute Disease; D000368:Aged; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D020644:Midline Thalamic Nuclei / Q000033:anatomy & histology* / Q000601:surgery*; D019635:Neurosurgical Procedures / Q000379:methods; D017286:Polysomnography; D011183:Postoperative Complications; D007319:Sleep Initiation and Maintenance Disorders / Q000175:diagnosis / Q000209:etiology*; D012894:Sleep Stages / Q000502:physiology; D014202:Tremor / Q000175:diagnosis / Q000503:physiopathology* / Q000601:surgery*; D020651:Ventral Thalamic Nuclei / Q000033:anatomy & histology* / Q000601:surgery*