title: [Advances of sustained/controlled release pellets in traditional Chinese medicine].
abstract: Pellets are multiple-unit drug delivery system, which have good fluidity, release stability and uniformity. With preparation techniques and excipient materials gradually established, pellets play an important part in the development of sustained/controlled release drug delivery system. The recent advances in pellets including the release mechanism, preparation methods, excipients and the characteristics in vivo for the sustained/controlled release pellets in traditional Chinese medicine (TCM) were reviewed in order to provide the strategies and rational methods for further investigations and applications.
authors.affiliation: Center of Science and Technology, Shanghai University of Treditional Chinese Medicine, Shanghai 201203, China.
authors.forename: Li-Hua
authors.initials: LH
authors.lastname: Chen
authors.forename: Yi
authors.initials: Y
authors.lastname: Feng
authors.forename: De-Sheng
authors.initials: DS
authors.lastname: Xu
mesh_terms: D000818:Animals; D002214:Capsules; D003692:Delayed-Action Preparations / Q000737:chemistry*; D016503:Drug Delivery Systems; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage / Q000737:chemistry* / Q000302:isolation & purification; D006801:Humans; D008863:Microspheres; D010946:Plants, Medicinal / Q000737:chemistry*; D011092:Polyethylene Glycols / Q000737:chemistry; D013678:Technology, Pharmaceutical / Q000379:methods*
chemical_list: D002214:Capsules; D003692:Delayed-Action Preparations; D004365:Drugs, Chinese Herbal; D011092:Polyethylene Glycols