Nosocomial meningitis in neonates caused by Streptococcus agalactiae.
Streptococcus agalactiae is a rare cause of neonatal meningitis in the era of peripartum prophylaxis with prophylaxis with ampicillin in colonized/infected mothers. However 5 cases of meningitis among 171 cases of pediatric nosocomial meningitis database within last 15 years occurred. All 5 children were neonates (one VLBW and early gestation newborn), 2 after neurosurgery. All 5 cases were successfully cured with a combination of cefotaxim (or ceftazidim) plus aminoglycosides, in one case also with addition of vancomycin or ampicillin. However 3 of 5 cured patients had neurologic sequellae, two of them reversible hydrocephalus and in speech retardation.
Rudinsky
B
B
John Paul School of Missiology and Tropical Health, Bratislava, Slovakia.
Ondrusova
A
A
Bauer
F
F
Benca
J
J
Huttova
M
M
D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D003428:Cross Infection / Q000188:drug therapy / Q000209:etiology / Q000382:microbiology*; D006801:Humans; D006849:Hydrocephalus / Q000209:etiology; D007231:Infant, Newborn; D007805:Language Development Disorders / Q000209:etiology; D016920:Meningitis, Bacterial / Q000188:drug therapy / Q000209:etiology / Q000382:microbiology*; D035583:Rare Diseases; D012189:Retrospective Studies; D013290:Streptococcal Infections / Q000150:complications* / Q000188:drug therapy; D013292:Streptococcus agalactiae / Q000472:pathogenicity*
D000900:Anti-Bacterial Agents