Deprotection of a silyl group with mesoporous silica.
The triethylsilyl (TES) group of silyl ethers of several types is selectively and easily removed in the presence of a t-butyldimethylsilyl (TBDMS) group with a mesoporous silica MCM-41/MeOH heterogeneous system. Comparison of the efficiency was carried out among several solvents, and among such promoters as common zeolites and ion-exchange resins. Furthermore, FSM-16, another mesoporous silica, was examined for the possibility of recycling by re-calcination at 400 degrees C after the reaction.
Itoh
Akichika
A
Gifu Pharmaceutical University, Gifu, Japan. itoha@gifu-pu.ac.jp
Kodama
Tomohiro
T
Masaki
Yukio
Y
D007475:Ion Exchange Resins; D012822:Silicon Dioxide / Q000737:chemistry*; D021241:Spectrometry, Mass, Electrospray Ionization
D007475:Ion Exchange Resins; D012822:Silicon Dioxide