Gender differences in ventricular volumes and left ventricle ejection fraction estimated by myocardial perfusion imaging: comparison of Quantitative Gated SPECT (QGS) and Segami software programs.
OBJECTIVE
To test for gender differences in the measurements obtained by Segami and Quantitative Gated SPECT (QGS) software programs.


METHODS
181 asymptomatic individuals without heart disease were submitted to myocardial perfusion imaging. End-diastolic volumes (EDV), end-systolic volumes (ESV) and left ventricular ejection fraction (LVEF) were measured by QGS and Segami software programs to evaluate the influence of gender, age, weight, height, heart rate, systolic blood pressure, diastolic blood pressure, body mass index and body surface area.


RESULTS
The means in the QGS method were: EDV (women= 68 ml; men= 95 ml; p<0.001), LVEF (women= 66.24%; men= 58, 7%) and Segami: EDV (women= 137 ml; men= 174 ml), LVEF (women= 62.67%; men= 58, 52%). There were significant differences between men and women in the EDV (p<0.001), ESV (p<0.001) and LVEF (p=0.001) that persisted after adjusting for body surface area.


CONCLUSIONS
Ventricular volumes were significantly lower and LVEF was significantly higher in women, estimated by QGS or Segami software programs.
Yamada
Alice Tatsuko
AT
Instituto do Coração, Hospital das Clínicas, FM, USP, São Paulo, SP, Brazil. alice.yamada@incor.usp.br
Campos Neto
Guilherme de Carvalho
Gde C
Soares
José
J
Giorgi
Maria Clementina P
MC
Araújo
Fernando
F
Meneghetti
José Claudio
JC
Mansur
Alfredo José
AJ
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000465:Algorithms; D000704:Analysis of Variance; D001830:Body Surface Area; D003430:Cross-Sectional Studies; D005260:Female; D015637:Gated Blood-Pool Imaging / Q000379:methods*; D006352:Heart Ventricles / Q000000981:diagnostic imaging; D006801:Humans; D008297:Male; D008875:Middle Aged; D012737:Sex Factors; D012984:Software; D013318:Stroke Volume; D015899:Tomography, Emission-Computed, Single-Photon / Q000379:methods*; D016277:Ventricular Function, Left / Q000502:physiology*