title: Novel ebselen-porphyrin conjugates: synthesis and nucleic acid interaction study.
abstract: Novel porphyrins bearing ebselen (2-phenyl-1,2-benzisoselenazol-3[2H]-one) moiety were synthesized and characterized. Their interactions with herring sperm DNA were studied by means of UV-visible, fluorescence, circular dichroism spectroscopy, and gel electrophoresis.
authors.affiliation: Department of Chemistry, Wuhan University, Wuhan 430072, PR China.
authors.forename: Zhi
authors.initials: Z
authors.lastname: Xue
authors.forename: An-Xin
authors.initials: AX
authors.lastname: Hou
authors.forename: Daniel Wei-Jing
authors.initials: DW
authors.lastname: Kwong
authors.forename: Wai-Kwok
authors.initials: WK
authors.lastname: Wong
mesh_terms: D001393:Azoles / Q000737:chemistry*; D002942:Circular Dichroism; D054833:Isoindoles; D009696:Nucleic Acids / Q000737:chemistry*; D016566:Organoselenium Compounds / Q000737:chemistry*; D011166:Porphyrins / Q000737:chemistry*; D013050:Spectrometry, Fluorescence; D013056:Spectrophotometry, Ultraviolet
chemical_list: D001393:Azoles; D054833:Isoindoles; D009696:Nucleic Acids; D016566:Organoselenium Compounds; D011166:Porphyrins; C042986:ebselen