title: Pseudoaneurysm following laparoscopic cholecystectomy.
abstract: BACKGROUND
  Laparoscopic cholecystectomy (LC) is the operation of choice for removal of the gallbladder. Unrecognized bile duct injuries present with biliary peritonitis and systemic sepsis. Bile has been shown to cause damage to the vascular wall and therefore delay the healing of injured arteries leading to pseudoaneurysm formation. Failure to deal with bile leak and secondary infection may result in pseudoaneurysm formation. This study was to report the incidence and outcomes of pseudoaneurysm in patients with bile leak following LC referred to our hospital.
  
  
  METHODS
  A retrospective analysis of our prospectively maintained liver database using key words pseudoaneurysm, bile leak and bile duct injury following laparoscopic cholecystectomy from January 2000 to December 2005 was performed.
  
  
  RESULTS
  A total of 86 cases were referred with bile duct injury and bile leak following LC and of these, 4 patients (4.5%) developed hepatic artery pseudoaneurysm (HAP) presenting with haemobilia in 3 and massive intra-abdominal bleed in 1. Selective visceral angiography confirmed pseudoaneurysm of the right hepatic artery in 2 cases, cystic artery stump in one and an intact but ectatic hepatic artery with surgical clips closely applied to the right hepatic artery at the origin of the cystic artery in the fourth case. Effective hemostasis was achieved in 3 patients with coil embolization and the fourth patient required emergency laparotomy for severe bleeding and hemodynamic instability due to a ruptured right hepatic artery. Of the 3 patients treated with coil embolization, 2 developed late strictures of the common hepatic duct (CHD) requiring hepatico-jejunostomy and one developed a stricture of left hepatic duct. All the 4 patients are alive at a median follow up of 17 months (range 1 to 65) with normal liver function tests.
  
  
  CONCLUSIONS
  HAP is a rare and potentially life-threatening complication of LC. Biloma and subsequent infection are reported to be associated with pseudoaneurysm formation. Late duct stricture is common either due to unrecognized injury at LC or secondary to ischemia after embolization.
authors.affiliation: Institute of Liver Studies, Kings College Hospital, Denmark Hill, London SE5 9RS, UK.
authors.forename: Mansoor Ahmed
authors.initials: MA
authors.lastname: Madanur
authors.forename: Narendra
authors.initials: N
authors.lastname: Battula
authors.forename: Harsheet
authors.initials: H
authors.lastname: Sethi
authors.forename: Rahul
authors.initials: R
authors.lastname: Deshpande
authors.forename: Nigel
authors.initials: N
authors.lastname: Heaton
authors.forename: Mohamed
authors.initials: M
authors.lastname: Rela
mesh_terms: D017541:Aneurysm, False / Q000209:etiology* / Q000628:therapy; D017081:Cholecystectomy, Laparoscopic / Q000009:adverse effects*; D005260:Female; D006431:Hemobilia / Q000209:etiology; D006499:Hepatic Artery; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies