Central precocious puberty due to hypothalamic hamartoma in a 7-month-old infant girl.
Hypothalamic hamartomas (HH) are rare congenital lesions of the tuber cinereum presenting with the classic triad of gelastic epilepsy, central precocious puberty (CPP) and developmental delay. In light of the important and diverse consequences of precocious puberty for affected children and their families, a correct diagnosis without delay is imperative. We present here a rare case of a 7-month-old infant girl with CPP and HH who was successfully treated with depot gonadotropin-releasing hormone (GnRH) analogue is presented.
Rousso
I H
IH
2nd Department of Pediatrics, Aristotle University of Thessaloniki, Thessaloniki, Greece. roussoi@med.auth.gr
Kourti
M
M
Papandreou
D
D
Tragiannidis
A
A
Athanasiadou
F
F
D003692:Delayed-Action Preparations; D004958:Estradiol / Q000097:blood; D005260:Female; D005500:Follow-Up Studies; D007987:Gonadotropin-Releasing Hormone / Q000031:analogs & derivatives; D006222:Hamartoma / Q000150:complications* / Q000175:diagnosis; D006801:Humans; D007027:Hypothalamic Diseases / Q000150:complications* / Q000175:diagnosis; D007223:Infant; D007273:Injections, Intramuscular; D007986:Luteinizing Hormone / Q000097:blood; D008186:Luteolytic Agents / Q000008:administration & dosage; D008279:Magnetic Resonance Imaging; D011629:Puberty, Precocious / Q000097:blood / Q000188:drug therapy / Q000209:etiology*; D017329:Triptorelin Pamoate / Q000008:administration & dosage
D003692:Delayed-Action Preparations; D008186:Luteolytic Agents; D017329:Triptorelin Pamoate; D007987:Gonadotropin-Releasing Hormone; D004958:Estradiol; D007986:Luteinizing Hormone