title: Thrombin injection for acute hemorrhage following angiography.
abstract: Femoral arterial puncture is the main access for diagnostic and therapeutic intervention in vascular disease. Significant complications are unusual and include uncontrolled bleeding which usually requires surgery. We report the use of ultrasound-guided thrombin injection that prevented any immediate need for surgery in 2 cases of uncontrolled bleeding following femoral arteriography. Clinical presentations and treatment are reported, together with a review of the literature.
authors.affiliation: Nuffield Department of Surgery, John Radcliffe Hospital, Headington, Oxford, OX3 9DY, UK. tobyrichards@btinternet.com
authors.forename: T
authors.initials: T
authors.lastname: Richards
authors.forename: F J
authors.initials: FJ
authors.lastname: Mussai
authors.forename: J
authors.initials: J
authors.lastname: Phillips-Hughes
authors.forename: R
authors.initials: R
authors.lastname: Uberoi
authors.forename: P
authors.initials: P
authors.lastname: Boardman
mesh_terms: D000208:Acute Disease; D000368:Aged; D000369:Aged, 80 and over; D000792:Angiography; D015901:Angiography, Digital Subtraction; D000800:Angioplasty, Balloon; D005260:Female; D005263:Femoral Artery / Q000601:surgery*; D006801:Humans; D007267:Injections; D007511:Ischemia / Q000000981:diagnostic imaging / Q000628:therapy; D007866:Leg / Q000098:blood supply; D019106:Postoperative Hemorrhage / Q000175:diagnosis / Q000188:drug therapy*; D011677:Punctures; D013917:Thrombin / Q000008:administration & dosage*; D014057:Tomography, X-Ray Computed; D018616:Ultrasonography, Doppler, Duplex
chemical_list: D013917:Thrombin