title: [Effect of intestinal electrical stimulation on small bowel transit: experiment with healthy volunteers].
abstract: OBJECTIVE
  To investigate the effect of intestinal electrical stimulation (IES) on small bowel transit.
  
  
  METHODS
  Twelve healthy volunteers, 6 males and 6 females, aged 22 - 23, underwent IES. A nasal-gastric tube with 2 ring electrodes on the tip was incubated into the duodenum via endoscope. 100 ml 1m Ci (99)Tc(m) mixed non-absorbable liquid was infused via the tube. During the course continuous real IES was conducted or the electrodes were connected to the stimulator but not with the power source (sham IES). Scanning with gamma-video-camera was conducted every 10 seconds. The time for the isotope to enter the ileocecum first was measured so as to indicate the small bowel transit. Dyspeptic symptoms were scored by the subjects themselves.
  
  
  RESULTS
  (1) The time for the isotopes to enter the ileocecum in real IES session was (28 +/- 10) min, significantly lower than that in sham IES session [(39 +/- 17) min, P < 0.05]. (2) The dyspeptic symptom score during the real IES was 1.5, not significantly different from that before IES (1.0, P > 0.05), and the dyspeptic symptom score during the sham IES was 0.5, also not significantly different from that during real IES (P > 0.05).
  
  
  CONCLUSIONS
  IES is capable of accelerating small bowel transit with no effect on dyspeptic symptoms, which suggests that IES may be a potential therapeutic method on intestinal motility disorders.
authors.affiliation: Division of Gastroenterology, Union Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
authors.forename: Jin-Song
authors.initials: JS
authors.lastname: Liu
authors.forename: Xiao-Hua
authors.initials: XH
authors.lastname: Hou
authors.forename: J D Z
authors.initials: JD
authors.lastname: Chen
mesh_terms: D000328:Adult; D004386:Duodenum / Q000502:physiology; D004558:Electric Stimulation / Q000295:instrumentation / Q000379:methods; D005260:Female; D005769:Gastrointestinal Motility / Q000502:physiology; D005772:Gastrointestinal Transit / Q000502:physiology*; D006801:Humans; D007421:Intestine, Small / Q000502:physiology*; D008297:Male