title: Psychosis and EEG abnormalities as manifestations of Hashimoto encephalopathy.
abstract: Hashimoto encephalopathy (HE) is a distinct form of encephalopathy, which can manifest itself with purely psychiatric symptoms. A 38-year-old female with history of rheumatoid arthritis was treated with psychotropic drugs for a couple of years in psychiatric structures because of the onset of depressive symptoms, psychoticlike manifestations, and impairment of cognitive functions. The electroencephalography (EEG) was characterized by general slowing with high voltage (2 to 3 Hz) delta biphasic and triphasic waves. Once a firm diagnosis of HE was made, corticosteroid treatment resulted in resolution of her psychiatric symptoms, marked EEG improvement, and partial improvement in her cognitive functions. HE should be suspected in young females with history of autoimmune disorders and EEG abnormalities.
authors.affiliation: University Department of Neurology, Zagreb School of Medicine and University Hospital Center, Zagreb, Croatia.
authors.forename: Davor
authors.initials: D
authors.lastname: Sporis
authors.forename: Mario
authors.initials: M
authors.lastname: Habek
authors.forename: Zdenko
authors.initials: Z
authors.lastname: Mubrin
authors.forename: Zdravka
authors.initials: Z
authors.lastname: Poljaković
authors.forename: Sanja
authors.initials: S
authors.lastname: Hajnsek
authors.forename: Zdenka
authors.initials: Z
authors.lastname: Bence-Zigman
mesh_terms: D000328:Adult; D000928:Antidepressive Agents / Q000627:therapeutic use; D014150:Antipsychotic Agents / Q000627:therapeutic use; D001928:Brain Diseases, Metabolic / Q000175:diagnosis* / Q000209:etiology; D004569:Electroencephalography; D005260:Female; D050031:Hashimoto Disease / Q000150:complications / Q000175:diagnosis* / Q000523:psychology*; D006801:Humans; D011618:Psychotic Disorders / Q000175:diagnosis* / Q000209:etiology / Q000628:therapy
chemical_list: D000928:Antidepressive Agents; D014150:Antipsychotic Agents