title: Cytoprotective effect of Panax ginseng on gallic acid-induced toxicity in TM3 mouse Leydig cells.
abstract: Our previous study had demonstrated cytotoxicity of gallic acid on testicular cells with increasing the intracellular production of hydrogen peroxide. In the present study, the Panax ginseng root aqueous extract showed the cytoprotective effect on gallic acid-induced toxicity in TM3 mouse Leydig cells with decreasing the intracellular production of hydrogen peroxide.
authors.affiliation: College of Oriental Medicine, Kyungwon University, Seongnam 461-701, South Korea. hangl98@naver.com
authors.forename: Wansu H
authors.initials: WH
authors.lastname: Park
authors.forename: Mun Seog
authors.initials: MS
authors.lastname: Chang
authors.forename: Woong Mo
authors.initials: WM
authors.lastname: Yang
authors.forename: Hyunsu
authors.initials: H
authors.lastname: Bae
authors.forename: Nam Il
authors.initials: NI
authors.lastname: Kim
authors.forename: Seong Kyu
authors.initials: SK
authors.lastname: Park
mesh_terms: D000818:Animals; D002478:Cells, Cultured; D004305:Dose-Response Relationship, Drug; D005707:Gallic Acid; D006861:Hydrogen Peroxide / Q000378:metabolism; D007985:Leydig Cells / Q000187:drug effects / Q000378:metabolism; D008297:Male; D051379:Mice; D005894:Panax; D008517:Phytotherapy; D010936:Plant Extracts / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D018517:Plant Roots; D020011:Protective Agents / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use
chemical_list: D010936:Plant Extracts; D020011:Protective Agents; D005707:Gallic Acid; D006861:Hydrogen Peroxide