Transfusion-transmitted infections.
Although the risk of transfusion-transmitted infections today is lower than ever, the supply of safe blood products remains subject to contamination with known and yet to be identified human pathogens. Only continuous improvement and implementation of donor selection, sensitive screening tests and effective inactivation procedures can ensure the elimination, or at least reduction, of the risk of acquiring transfusion transmitted infections. In addition, ongoing education and up-to-date information regarding infectious agents that are potentially transmitted via blood components is necessary to promote the reporting of adverse events, an important component of transfusion transmitted disease surveillance. Thus, the collaboration of all parties involved in transfusion medicine, including national haemovigilance systems, is crucial for protecting a secure blood product supply from known and emerging blood-borne pathogens.
Bihl
Florian
F
Partners AIDS Research Center, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA. f.bihl@mac.com
Castelli
Damiano
D
Marincola
Francesco
F
Dodd
Roger Y
RY
Brander
Christian
C
D001424:Bacterial Infections / Q000209:etiology / Q000517:prevention & control; D018562:Disease Transmission, Infectious / Q000517:prevention & control*; D006801:Humans; D017096:Prion Diseases / Q000209:etiology / Q000517:prevention & control; D011528:Protozoan Infections / Q000209:etiology / Q000517:prevention & control; D065227:Transfusion Reaction; D014777:Virus Diseases / Q000209:etiology / Q000517:prevention & control