title: Enhanced category tuning revealed by intracranial electroencephalograms in high-order human visual areas.
abstract: The functional organization of human sensory cortex was studied by comparing intracranial EEG (iEEG) recordings of local field potentials in neurosurgical patients with functional magnetic resonance imaging (fMRI) obtained in healthy subjects. Using naturalistic movie stimuli, we found a tight correlation between these two measures throughout the human sensory cortex. Importantly, the correlation between the iEEG and fMRI signals was site-specific, exhibiting neuroanatomically specific coupling. In several cortical sites the iEEG activity was confined strictly to one object category. This site selectivity was not limited to faces but included other object categories such as houses and tools. The selectivity of the iEEG signals to images of different object categories was remarkably higher when compared with the selectivity of the corresponding fMRI signals. A plausible interpretation of the fMRI and iEEG results concerns cortical organization in which object categories are organized in a mosaic of narrowly tuned object-selective clusters.
authors.affiliation: School of Computer Science, Sackler Faculty of Exact Sciences, Tel Aviv University, Tel Aviv 69978, Israel.
authors.forename: Eran
authors.initials: E
authors.lastname: Privman
authors.forename: Yuval
authors.initials: Y
authors.lastname: Nir
authors.forename: Uri
authors.initials: U
authors.lastname: Kramer
authors.forename: Svetlana
authors.initials: S
authors.lastname: Kipervasser
authors.forename: Fani
authors.initials: F
authors.lastname: Andelman
authors.forename: Miri Y
authors.initials: MY
authors.lastname: Neufeld
authors.forename: Roy
authors.initials: R
authors.lastname: Mukamel
authors.forename: Yehezkel
authors.initials: Y
authors.lastname: Yeshurun
authors.forename: Itzhak
authors.initials: I
authors.lastname: Fried
authors.forename: Rafael
authors.initials: R
authors.lastname: Malach
mesh_terms: D004567:Electrodes, Implanted; D004569:Electroencephalography / Q000295:instrumentation / Q000379:methods*; D005074:Evoked Potentials, Visual / Q000502:physiology; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D010364:Pattern Recognition, Visual / Q000145:classification* / Q000502:physiology*; D010775:Photic Stimulation / Q000379:methods*; D014793:Visual Cortex / Q000502:physiology*