title: Long-term outcome, colonic motility, and sphincter performance after Swenson's procedure for Hirschsprung's disease: a single-center 2-decade experience with 346 cases.
abstract: BACKGROUND
  The aim of this study is to explore the long-term outcome and the colon and sphincter function in children undergoing the Swenson's operation for Hirschsprung's disease (HD).
  
  
  METHODS
  Three hundred forty-six children (266 males and 80 females) undergoing Swenson's operation for HD for 8 to 20 years were followed up. Barium enema and defecography, total and segmental colonic transit time with the simplified radioopaque markers, and the anorectal vector manometry were used.
  
  
  RESULTS
  Stooling patterns were fair in most patients, and the functional examinations were abnormal in few cases.
  
  
  CONCLUSIONS
  The long-term outcome is satisfactory in most of the children undergoing the Swenson's operation for HD, but it is still not as good as what the surgeons have expected. This is probably because of the abnormal colonic motility and/or the dysfunctions of the internal anal sphincter.
authors.affiliation: Department of Pediatric Surgery, The Second Affiliated Hospital, China Medical University, No. 36 Sanhao Street, Heping District, Shenyang, China 110004.
authors.forename: Shu-Cheng
authors.initials: SC
authors.lastname: Zhang
authors.forename: Yu-Zuo
authors.initials: YZ
authors.lastname: Bai
authors.forename: Wei
authors.initials: W
authors.lastname: Wang
authors.forename: Wei-Lin
authors.initials: WL
authors.lastname: Wang
mesh_terms: D001003:Anal Canal / Q000503:physiopathology; D002648:Child; D002675:Child, Preschool; D003672:Defecation; D005260:Female; D005500:Follow-Up Studies; D005769:Gastrointestinal Motility; D006627:Hirschsprung Disease / Q000503:physiopathology* / Q000601:surgery*; D006801:Humans; D007223:Infant; D008297:Male; D008365:Manometry; D020127:Recovery of Function; D012189:Retrospective Studies; D016896:Treatment Outcome