Modelling the geometric features and investigating electrical properties of dendrites in a fish thalamic neuron.
A certain pacific fish has a thalamic nerve cell with a unique dendritic geometry. Instead of the cell having a branching dendritic structure, the large cell of the corpus glomerulosum has, generally, a single dendritic stalk with a large bulbous tip. We formulate a cable-theory model that incorporates the geometry, and then, we solve the problem for a single, localized synaptic current source at the bulb. From the solution representation, we numerically examine the characteristics of the postsynaptic potential due to the presence of the bulbous tip.
Krzyzanski
Wojciech
W
Department of Pharamaceutical Sciences, University of Buffalo, State University of New York, Buffalo, NY 14260, USA. wk@buffalo.edu
Bell
Jonathan
J
D000465:Algorithms; D000818:Animals; D003712:Dendrites / Q000502:physiology*; D025802:Electric Capacitance; D017097:Electric Impedance; D004594:Electrophysiology; D019706:Excitatory Postsynaptic Potentials / Q000502:physiology; D008564:Membrane Potentials / Q000502:physiology; D008954:Models, Biological; D009474:Neurons / Q000502:physiology*; D013570:Synaptic Membranes / Q000502:physiology; D023721:Tetraodontiformes / Q000502:physiology*; D013787:Thalamic Nuclei / Q000166:cytology