title: Cystic adventitial disease of the popliteal artery: an argument for the developmental theory.
abstract: Cystic adventitial disease is a rare non-atheromatous cause of popliteal artery disease. We report a case of a 54-year-old patient with claudication of the right calf caused by cystic adventitial disease. Intra-operatively, a communication between the adventitia and the knee joint was identified. Connections between the adventitial cyst and the nearby joint have been reported in the literature that support the developmental theory. This theory suggests that cystic adventitial disease is a developmental manifestation of mucin-secreting cells derived from the mesenchyme of the adjacent joint. This case is the first, to our knowledge, in which a communication between joint and adventitia has been clearly documented by operative findings.
authors.affiliation: Chirurgische Klinik/Gefässmedizin, Franziskus-Krankenhaus, Akademisches Lehrkrankenhaus der Charité-Universitätsmedizin, Berlin, Germany.
authors.forename: Nikolaos
authors.initials: N
authors.lastname: Tsilimparis
authors.forename: Ulrich
authors.initials: U
authors.lastname: Hanack
authors.forename: Sharom
authors.initials: S
authors.lastname: Yousefi
authors.forename: Pavlos
authors.initials: P
authors.lastname: Alevizakos
authors.forename: Ralph I
authors.initials: RI
authors.lastname: Rückert
mesh_terms: D001157:Arterial Occlusive Diseases / Q000150:complications* / Q000209:etiology / Q000473:pathology; D003238:Connective Tissue / Q000473:pathology* / Q000601:surgery; D006801:Humans; D007383:Intermittent Claudication / Q000209:etiology* / Q000473:pathology; D007719:Knee Joint / Q000473:pathology; D008297:Male; D008875:Middle Aged; D011150:Popliteal Artery / Q000473:pathology* / Q000601:surgery; D011151:Popliteal Cyst / Q000150:complications / Q000175:diagnosis* / Q000209:etiology / Q000473:pathology / Q000601:surgery; D012501:Saphenous Vein / Q000637:transplantation; D016896:Treatment Outcome; D014656:Vascular Surgical Procedures