Remission of progressive multifocal leukoencephalopathy and primary central nervous system lymphoma in an HIV-infected patient.
The coexistence of progressive multifocal leukoencephalopathy (PML) and primary central nervous system lymphoma (PCNSL) is a rare event, usually associated with a fatal outcome. We report the case of a human immunodeficiency virus (HIV)-infected individual presenting with both PML and PCNSL who made a remarkable recovery after highly active anti retroviral therapy (HAART) and radiation therapy, and discuss diagnostic and therapeutic aspects of both conditions.
Lima
M A
MA
Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.
Katz-Brull
R
R
Lenkinski
R E
RE
Nunez
R
R
Feinrider
D
D
Koralnik
I J
IJ
D000328:Adult; D016543:Central Nervous System Neoplasms / Q000209:etiology* / Q000821:virology; D018450:Disease Progression; D015658:HIV Infections / Q000150:complications*; D006801:Humans; D007968:Leukoencephalopathy, Progressive Multifocal / Q000209:etiology* / Q000821:virology; D008223:Lymphoma / Q000209:etiology* / Q000821:virology; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male