title: Osteobiologics.
abstract: Osteobiologic adjuvants that aid in bone grafting have recently been popularized. Current osteobiologic technologies can be organized into 3 main categories: osteoconductive, osteogenic, and osteoinductive. Appropriate use of osteobiologic agents mimics autograft. Compared with autograft , synthetic adjuvants minimize donor morbidity. Understanding how synthetic agents can enhance bone formation and their appropriate use can aid the orthopedic surgeon in delivering optimal care in these difficult cases. The understanding of how synthetic grafts can enhance the normal bone healing cascade defines their role and use in treating fracture gaps.
authors.affiliation: St. Anthony's Central Hospital, Panorama Orthopedic Clinic and Spine Center, Denver, Colorado, USA.
authors.forename: Bharat M
authors.initials: BM
authors.lastname: Desai
mesh_terms: D001672:Biocompatible Materials; D001843:Bone Cements; D001854:Bone Marrow Cells; D018786:Bone Substitutes / Q000627:therapeutic use*; D005260:Female; D005592:Fracture Fixation / Q000379:methods*; D017759:Fractures, Malunited; D006801:Humans; D008297:Male; D019637:Orthopedic Procedures; D010012:Osteogenesis
chemical_list: D001672:Biocompatible Materials; D001843:Bone Cements; D018786:Bone Substitutes