title: [Infertility and testicular seminoma].
abstract: BACKGROUND
  Infertility in men may be associated with an elevated risk of testicular cancer. The authors report a case of testicular seminoma discovered fortuitously during a workup for infertility.
  
  
  METHODS
  A 30 year-old male was seen for infertility. Physical examination and testicular ultrasonography were normal. The sperm count found oligoasthenospermia related to the excretory ducts. The patient underwent testicular biopsies for infertility, which showed an intratubular germ cell tumor. Tumor markers (beta HCG, alpha FP, LDH) were normal. Computed tomography was normal for the thorax, abdomen, and pelvis. We performed an inguinal orchiectomy. The pathology examination found seminoma, at a pT1 stage. One course of chemotherapy followed.
  
  
  CONCLUSIONS
  The incidence of testicular cancer is increasing throughout the world. Recent studies show a strong relation between infertility and an increased risk of testicular cancer, and some authors even suggest a causal relation.
authors.affiliation: Service d'urologie, Hôpital Tenon, Paris. aminlakmich@yahoo.com
authors.forename: Mohamed Amine
authors.initials: MA
authors.lastname: Lakmichi
authors.forename: Lamine
authors.initials: L
authors.lastname: Niang
authors.forename: Mohamed
authors.initials: M
authors.lastname: Tligui
authors.forename: Olivier
authors.initials: O
authors.lastname: Traxer
authors.forename: Olivier
authors.initials: O
authors.lastname: Cussenot
authors.forename: Bernard
authors.initials: B
authors.lastname: Gattegno
authors.forename: Philippe
authors.initials: P
authors.lastname: Thibault
authors.forename: Philippe
authors.initials: P
authors.lastname: Sebe
mesh_terms: D000328:Adult; D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000627:therapeutic use; D001706:Biopsy; D016190:Carboplatin / Q000008:administration & dosage / Q000627:therapeutic use; D006801:Humans; D007248:Infertility, Male / Q000175:diagnosis* / Q000209:etiology; D008297:Male; D009367:Neoplasm Staging; D009919:Orchiectomy; D018239:Seminoma / Q000188:drug therapy / Q000473:pathology / Q000601:surgery; D013076:Sperm Count; D013736:Testicular Neoplasms / Q000188:drug therapy / Q000473:pathology / Q000601:surgery; D013737:Testis / Q000473:pathology
chemical_list: D000970:Antineoplastic Agents; D016190:Carboplatin