title: Enantioselective synthesis of trifluoromethyl-substituted cyclopropanes.
abstract: The reaction of 1-aryl-2,2,2-trifluorodiazoethanes with alkenes, catalyzed by the adamantylglycine-derived dirhodium complex Rh2(R-PTAD)4, generates trifluoromethyl-substituted cyclopropanes with high diastereoselectivity (>94%) and enantioselectivity (88->98%).
authors.affiliation: Department of Chemistry, University at Buffalo, The State University of New York, Buffalo, NY 14260-3000, USA.
authors.forename: Justin R
authors.initials: JR
authors.lastname: Denton
authors.forename: Dinesh
authors.initials: D
authors.lastname: Sukumaran
authors.forename: Huw M L
authors.initials: HM
authors.lastname: Davies