title: Chromoblastomycosis in Nepal: a study of 13 cases.
abstract: BACKGROUND
  Chromoblastomycosis is a chronic fungal infection caused by several pigmented fungi commonly seen in tropical and subtropical climates.
  
  
  OBJECTIVE
  To evaluate the epidemiologic, clinical and pathological characteristics of chromoblastomycosis in our patients.
  
  
  METHODS
  This retrospective and prospective study was conducted at the Manipal Teaching Hospital, Pokhara, Nepal. Clinical features and histopathology of all the cases diagnosed as chromoblastomycosis during the last eight years were studied.
  
  
  RESULTS
  A total of 13 cases of chromoblastomycosis were diagnosed during the period of 1999-2006. The disease was seen predominantly in middle-aged male farmers and those from rural areas. The lesions commonly involved the lower extremity and were single or multiple in number. They clinically presented as verrucous or nodular growths. Out of these 13 cases, three were diagnosed clinically as squamous cell carcinoma and one as psoriasis. The histopathological features included sclerotic bodies in 12 cases (92%), microabscess formation in 10 cases (76.9%), pseudoepitheliomatous hyperplasia in nine cases (69.2%) and granuloma in eight cases (61.5%).
  
  
  CONCLUSIONS
  Farming is the commonest occupation in patients with chromoblastomycosis. Early histological diagnosis helps in effective management of the condition.
authors.affiliation: Department of Pathology, Manipal College of Medical Science and Manipal Teaching Hospital, Pokhara, Nepal. pradhanseema30@yahoo.com
authors.forename: Seema V
authors.initials: SV
authors.lastname: Pradhan
authors.forename: O P
authors.initials: OP
authors.lastname: Talwar
authors.forename: Arnab
authors.initials: A
authors.lastname: Ghosh
authors.forename: Ravi M
authors.initials: RM
authors.lastname: Swami
authors.forename: K C
authors.initials: KC
authors.lastname: Shiva Raj
authors.forename: Sanjeev
authors.initials: S
authors.lastname: Gupta
mesh_terms: D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000368:Aged; D001132:Arm; D002862:Chromoblastomycosis / Q000453:epidemiology* / Q000473:pathology* / Q000628:therapy; D005145:Face; D005260:Female; D006784:Hospitals, Teaching; D006801:Humans; D007866:Leg; D008297:Male; D008875:Middle Aged; D009390:Nepal; D012307:Risk Factors; D012423:Rural Health; D017678:Sex Distribution