title: Microsurgical treatment of symptomatic sacral perineurial cysts.
abstract: OBJECTIVE
  The aim of this study was to investigate the microsurgical results of symptomatic sacral perineurial cysts of 11 patients and to discuss the treatment options of the past 10 years.
  
  
  METHODS
  We retrospectively reviewed the records of 11 patients with symptomatic sacral perineurial cysts who underwent microsurgical treatment at Tongji Hospital, Huazhong University of Science and Technology from 1993 through 2006. The philosophy was to perform total or partial cyst wall removal, to imbricate the remaining nerve sheath if possible, and to repair local defect with muscle, Gelfoam (Pharmacia & Upjohn, Kalamazoo, MI), and fibrin glue. Patient outcomes were assessed by comparing the preoperative and postoperative examination results. The average follow-up time obtained from return visits to the neurosurgery clinic or by telephone questionnaires ranged from 2 months to 13 years. A literature search and analysis of current treatment options were performed.
  
  
  RESULTS
  Nine of the 11 patients (82%) experienced complete or substantial relief of their preoperative symptoms. One patient (Patient 4) experienced worsening of bladder dysfunction after surgery and recovered slowly to subnormal function during the subsequent 2 months. The symptoms of Patient 9 did not resolve, and magnetic resonance imaging showed that the cyst had reoccurred. The patient underwent reoperation 3 months later without any improvement. One patient (Patient 11) experience a cerebrospinal fluid leakage complication. Neither new postoperative neurological defects nor infection were observed in our series. In the literature, there are six different treatment options under debate and controversially discussed.
  
  
  CONCLUSIONS
  Microsurgical treatment yielded the best long-term resolution of patient symptoms to date and should be recommended to appropriately selected patients.
authors.affiliation: Department of Neurosurgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. guodongsheng@yahoo.com
authors.forename: Dongsheng
authors.initials: D
authors.lastname: Guo
authors.forename: Kai
authors.initials: K
authors.lastname: Shu
authors.forename: Rudong
authors.initials: R
authors.lastname: Chen
authors.forename: Changshu
authors.initials: C
authors.lastname: Ke
authors.forename: Yanchang
authors.initials: Y
authors.lastname: Zhu
authors.forename: Ting
authors.initials: T
authors.lastname: Lei
mesh_terms: D000328:Adult; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008866:Microsurgery; D020127:Recovery of Function; D012189:Retrospective Studies; D012445:Sacrococcygeal Region; D052958:Tarlov Cysts / Q000150:complications / Q000473:pathology / Q000601:surgery*; D016896:Treatment Outcome