[Treatment of asthma and rhinitis during pregnancy and breast feeding].
Inhaled therapies are preferred to systemic ones during pregnancy and breast feeding. A real paradox exists however between the necessity to ensure an optimal treatment for pregnant women with asthma, in order to prevent fetal hypoxia, and the precaution linked to any drug prescription during pregnancy. Thus, the use of topical corticosteroids remains the first choice for asthma as well as rhinitis. Inhaled beta2-agonists are also recommended. Systemic corticosteroids may however be prescribed without hesitation when their use is required for asthma treatment. It is also interesting to note that oral second-generation antihistamines are currently allowed during pregnancy and breast feeding. This type of antihistamines is indeed to be preferred to first-generation ones that generate more side-effects and generally are thus not to be prescribed during breast feeding.
Leimgruber
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Service d'immunologie et d'allergie CHUV, 1011 Lausanne. Annette.Leimgruber@chuv.ch
D001249:Asthma / Q000188:drug therapy*; D000075202:Contraindications; D005260:Female; D006801:Humans; D007167:Immunotherapy; D011247:Pregnancy; D011248:Pregnancy Complications / Q000188:drug therapy*; D012220:Rhinitis / Q000188:drug therapy*