title: Rotavirus associated acute encephalitis/encephalopathy and concurrent cerebellitis: report of two cases.
abstract: It is known that rotavirus gastroenteritis can accompany some neurological manifestations, including encephalitis/encephalopathy or seizures. However, the detailed pathogenesis involved has not been fully understood. To date, acute cerebellitis associated rotavirus gastroenteritis has not been previously reported, except for one case. Herein, we describe two cases of acute encephalitis/encephalopathy and concurrent cerebellitis, associated rotavirus gastroenteritis. Following vomiting and diarrhea, case 1 experienced convulsions and consciousness disturbance and case 2, transient loss of consciousness with eye deviation. After these symptoms subsided, cerebellar signs became evident and a brain MRI showed cerebellar involvement in both cases. Both cases showed speech disturbances, such as mutism, slow speech and dysarthria. In this report, we will discuss the possible pathogenesis of rotavirus associated acute encephalitis/encephalopathy and concurrent cerebellitis.
authors.affiliation: Department of Neurology, Gunma Children's Medical Center, 779 Shimohakoda, Hokkitsu-machi, Shibukawa, Gunma 377-8577, Japan. shiihara-ind@umin.net
authors.forename: Takashi
authors.initials: T
authors.lastname: Shiihara
authors.forename: Mio
authors.initials: M
authors.lastname: Watanabe
authors.forename: Ayako
authors.initials: A
authors.lastname: Honma
authors.forename: Masahiko
authors.initials: M
authors.lastname: Kato
authors.forename: Yukio
authors.initials: Y
authors.lastname: Morita
authors.forename: Takashi
authors.initials: T
authors.lastname: Ichiyama
authors.forename: Kenichi
authors.initials: K
authors.lastname: Maruyama
mesh_terms: D002526:Cerebellar Diseases / Q000209:etiology / Q000473:pathology / Q000821:virology*; D002675:Child, Preschool; D004660:Encephalitis / Q000209:etiology / Q000473:pathology / Q000821:virology*; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D012401:Rotavirus / Q000472:pathogenicity*; D012400:Rotavirus Infections / Q000150:complications* / Q000473:pathology