title: Macular hole and intravitreal injection of triamcinolone acetonide for macular edema due to central retinal vein occlusion.
abstract: OBJECTIVE
  To report a case of macular hole progression after intravitreal injection of triamcinolone acetonide (IVTA) for chronic macular edema secondary to nonischemic central retinal vein occlusion (CRVO).
  
  
  METHODS
  A 33-year-old woman with massive macular edema after CRVO underwent IVTA. Optical coherence tomography (OCT) and fluorescein angiography were performed before and after the procedure.
  
  
  RESULTS
  At the 1-week IVTA injection control, the patient's best-corrected visual acuity improved from 20/400 to 20/200 and OCT detected a progression of macular hole stage.
  
  
  CONCLUSIONS
  IVTA steroid injection may provide a significant improvement in macular edema, but injection-related complications may occur such as this uncommon macular reaction resulting in permanent visual loss.
authors.affiliation: Department of Ophthalmology, San Raffaele Scientific Institute, Milano, Italy. lattanzio.rosangela@hsr.it
authors.forename: R
authors.initials: R
authors.lastname: Lattanzio
authors.forename: A
authors.initials: A
authors.lastname: Ramoni
authors.forename: F
authors.initials: F
authors.lastname: Scotti
authors.forename: U
authors.initials: U
authors.lastname: Introini
mesh_terms: D000328:Adult; D018450:Disease Progression; D005260:Female; D005451:Fluorescein Angiography; D005938:Glucocorticoids / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D007267:Injections; D008269:Macular Edema / Q000188:drug therapy* / Q000209:etiology; D033401:Microscopy, Acoustic; D012167:Retinal Perforations / Q000139:chemically induced* / Q000175:diagnosis / Q000503:physiopathology; D012170:Retinal Vein Occlusion / Q000150:complications*; D041623:Tomography, Optical Coherence; D014222:Triamcinolone Acetonide / Q000009:adverse effects* / Q000627:therapeutic use; D014792:Visual Acuity; D014822:Vitreous Body
chemical_list: D005938:Glucocorticoids; D014222:Triamcinolone Acetonide