Urachal duct remnant-like umbilical clear cell acanthoma in an infant: an unusual presentation and pitfall in clinical practice.
BACKGROUND
Although an umbilical nodule is common in neonates and young infants, an umbilical nodule of poor therapeutic response will increase the likelihood of other uncommon etiology. Clear cell acanthoma (CCA) has never been described as an oozing umbilical nodule on infants.


METHODS
To present a case of CCA which occurred on an 8-month-old female infant presenting with one weeping nodule on the umbilicus since early neonate. The lesion underwent skin biopsy and subsequent hematoxylin-eosin and periodic acid-Schiff staining.


RESULTS
Three courses of liquid nitrogen cryosurgery were performed after the diagnosis of CCA was confirmed. The lesion resolved rapidly.


CONCLUSIONS
This report presents the first and youngest case of umbilical CCA in the English literature. This case supports the inflammatory dermatosic nature of CCA.
Hsu
Hsiu-cheng
HC
Department of Dermatology, Chang Gung Memorial Hospital, Taipei, Taiwan.
Yang
Chih-Hsun
CH
Kuo
Tseng-tong
TT
Shih
I-Hsin
IH
Hong
Hong-Shang
HS
D049309:Acanthoma / Q000473:pathology* / Q000628:therapy; D000013:Congenital Abnormalities; D003937:Diagnosis, Differential; D005122:Exudates and Transudates; D005260:Female; D006801:Humans; D007223:Infant; D012878:Skin Neoplasms / Q000473:pathology* / Q000628:therapy; D014472:Umbilicus / Q000002:abnormalities / Q000473:pathology*