Antiepileptic drugs and visual function.
Antiepileptic drugs are known to result in visual disturbances. A number of antiepileptic drugs have recently been reported to result in various abnormalities of vision, particularly deficiencies in visual fields and color vision. Moreover, there has been a marked improvement in the diagnosis and understanding of the pathophysiology of visual disturbance. This review collects evidence for visual adverse effects induced by the older antiepileptic drugs (barbiturates, benzodiazepine, carbamazepine, valproic acid, ethosuximide, and phenytoin) and the newer ones (vigabatrin, topiramate, tiagabine, levetiracetam, lamotrigine, gabapentin, felbamate, and oxcarbazepine).
Verrotti
Alberto
A
Department of Pediatrics, University of Chieti, Chieti, Italy. averrott@unich.it
Manco
Rossella
R
Matricardi
Sara
S
Franzoni
Emilio
E
Chiarelli
Francesco
F
D000927:Anticonvulsants / Q000009:adverse effects*; D002648:Child; D004827:Epilepsy / Q000188:drug therapy*; D006801:Humans; D014786:Vision Disorders / Q000139:chemically induced* / Q000503:physiopathology
D000927:Anticonvulsants