Recent developments in asymmetric transfer hydrogenation with Hantzsch esters: a biomimetic approach.
By utilizing Hantzsch esters as the hydrogen source, asymmetric transfer hydrogenation of C=C, C=N, and C=O is realized in the presence of an organocatalyst or a metal-ligand complex, thus affording versatile chiral building blocks in high yields with excellent enantioselectivities under mild conditions. A detailed discussion of recent findings and an assessment of this biomimetic approach are presented in this review.
You
Shu-Li
SL
State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 354 Fenglin Lu, Shanghai 200032, China. slyou@mail.sioc.ac.cn
D002384:Catalysis; D004952:Esters; D006859:Hydrogen / Q000737:chemistry*; D018716:Molecular Mimicry; D013237:Stereoisomerism
D004952:Esters; D006859:Hydrogen