Novel base catalysed rearrangement of sultone oximes to 1,2-benzisoxazole-3-methane sulfonate derivatives.
A new process for the preparation of 1,2-benzisoxazole-3-methanesulfonates and 4-oximino-2,3-dihydrobenzoxathiin-2,2-dioxides (sultone oximes) is described. These compounds are important intermediates for the preparation of zonisamide, an anti-convulsant drug.
Arava
Veera Reddy
VR
Research and Development Laboratories, Suven Life Sciences Ltd,, # 18, Phase - III, Jeedimetla, Hyderabad - 500055, India. reddyvenis@rediffmail.com
Siripalli
Udaya Bhaskara Rao
UB
Nadkarni
Vaishali
V
Chinnapillai
Rajendiran
R