Tree Gibbs Sampler: identifying conserved motifs without aligning orthologous sequences.
CONCLUSIONS
Tree Gibbs Sampler is a software for identifying motifs by simultaneously using the motif overrepresentation property and the motif evolutionary conservation property. It identifies motifs without depending on pre-aligned orthologous sequences, which makes it useful for the extraction of regulatory elements in multiple genomes of both closely related and distant species.


BACKGROUND
The Tree Gibbs Sampler software is freely downloadable at https://compbio.iupui.edu/xiaomanli/LiSoftware/retrieve.php?ID=tgs
Cai
Xiaohui
X
Division of Biostatistics, School of Medicine, Indiana University, Indianapolis, IN 46202, USA.
Hu
Haiyan
H
Li
Xiaoman Shawn
XS
D000465:Algorithms; D020816:Amino Acid Motifs / Q000235:genetics*; D017124:Conserved Sequence / Q000235:genetics*; D019143:Evolution, Molecular; D011506:Proteins / Q000235:genetics*; D016415:Sequence Alignment / Q000379:methods; D017422:Sequence Analysis, DNA / Q000379:methods*; D012689:Sequence Homology, Nucleic Acid; D012984:Software
D011506:Proteins