title: What influences clinicians' operative preferences for women with breast cancer? An application of the discrete choice experiment.
abstract: BACKGROUND
  Little is known regarding cancer clinicians' treatment preferences.
  
  
  OBJECTIVE
  Determine the impact of pre-operative variables over specialist breast clinicians' operative preferences using discrete choice experiment methodology.
  
  
  METHODS
  Cross-sectional survey of operative preferences to hypothetical scenarios based on: patient age, bra cup size, cancer size, site and focality.
  
  
  RESULTS
  73% response rate (68/93). Multinomial logistic regression across scenarios (n=1695) with allowance for response clustering, comparing equal preference for mastectomy and breast conservation surgery (BCS) with preference for mastectomy or BCS. Increasing patient age, cancer size, central site, multi-focality and reducing cup size, all associated with preference for mastectomy, over equal preference, over BCS (p<0.001). Doctors preferred specific treatments, females and nurses avoided mastectomy (p=0.015 and p<0.001 respectively).
  
  
  CONCLUSIONS
  Clinician preferences were predominantly treatment guideline congruent, but significantly influenced by patient age, clinician gender and occupation. This methodology is capable of elucidating treatment preferences and could be applied elsewhere where treatment options and practice variability exist.
authors.affiliation: Academic Surgical Oncology Unit, The University of Sheffield, Floor K, Royal Hallamshire Hospital, Sheffield S10 2JF, UK. l.caldon@sheffield.ac.uk
authors.forename: Lisa J M
authors.initials: LJ
authors.lastname: Caldon
authors.forename: Stephen J
authors.initials: SJ
authors.lastname: Walters
authors.forename: Julie
authors.initials: J
authors.lastname: Ratcliffe
authors.forename: Malcolm W R
authors.initials: MW
authors.lastname: Reed
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001943:Breast Neoplasms / Q000601:surgery*; D002755:Choice Behavior; D003430:Cross-Sectional Studies; D004739:England; D005260:Female; D006801:Humans; D008297:Male; D008408:Mastectomy / Q000379:methods; D008505:Medical Staff, Hospital / Q000592:standards*; D008875:Middle Aged; D011364:Professional Practice; D012044:Regression Analysis; D011795:Surveys and Questionnaires