Highly selective synthesis of oxabicycloalkanes by indium tribromide-mediated cyclization reactions of epoxyalkenes.
The cyclization of epoxyalkenes to oxabicycloalkanes is catalyzed by stoichiometric quantities of indium tribromide which exhibits excellent selectivity giving the oxabicyclic product in high yield in preference to other cyclized or rearrangement products.
Smith
Brendan M
BM
Department of Chemistry, University of Wales Swansea, Swansea, UK.
Skellam
Elizabeth J
EJ
Oxley
Samantha J
SJ
Graham
Andrew E
AE