Surgical treatment for obesity and its impact on non-alcoholic steatohepatitis.
Non-alcoholic steatohepatitis (NASH) in obese and severely obese populations is associated with the metabolic syndrome, with features of the syndrome predicting those who will have NASH rather than simple steatosis, a more benign form of non-alcoholic fatty liver disease. Substantial weight loss is proving the most effective therapy for obesity-related conditions. Improvements have seen the development of less invasive procedures. There is growing evidence that laparoscopic adjustable gastric banding and roux-en-Y gastric bypass provide effective therapy.
Dixon
John B
JB
Australian Centre for Obesity Research and Education, Monash University, Alfred Hospital, Melbourne, Victoria, Australia. john.dixon@med.monash.edu.au
D050110:Bariatric Surgery; D005234:Fatty Liver / Q000209:etiology / Q000503:physiopathology / Q000517:prevention & control*; D006505:Hepatitis / Q000209:etiology / Q000503:physiopathology / Q000517:prevention & control*; D006801:Humans; D009765:Obesity / Q000150:complications* / Q000503:physiopathology / Q000601:surgery*; D015431:Weight Loss / Q000502:physiology