title: Development of a validation protocol to determine the ability of screw-top containers to be watertight and to withstand impact damage from accidental dropping.
abstract: Polypropylene screw-top containers are used to collect, transport and store a variety of tissues within tissue banks. These containers are validated for use by tissue banks but no standard validation protocol is used. We present here a protocol for testing screw-top containers for leakage, evaporation and the ability to withstand accidental impact damage. Three different containers were tested, MedFor S072, MedFor S277 and MacoPharma PROT0483. The validation can detect differences between different manufacturer's containers and this protocol will be used in future validations of screw-top containers within National Blood Service Tissue Services.
authors.affiliation: Tissue Development Laboratory, National Health Service Blood and Transplant, National Blood Service Tissue Services, Estuary Banks, Speke, Liverpool L24 8RB, UK. mark.eagle@nbs.nhs.uk
authors.forename: M J
authors.initials: MJ
authors.lastname: Eagle
authors.forename: P
authors.initials: P
authors.lastname: Rooney
authors.forename: J N
authors.initials: JN
authors.lastname: Kearney
mesh_terms: D002985:Clinical Protocols; D008422:Materials Testing; D011126:Polypropylenes; D019064:Product Packaging; D013048:Specimen Handling / Q000295:instrumentation* / Q000379:methods; D014015:Tissue Banks
chemical_list: D011126:Polypropylenes