Stereoselective construction of fluorinated indanone derivatives via a triple cascade Lewis acid-catalyzed reaction.
A one-pot three-component cascade reaction proceeds by way of a Lewis acid-catalyzed Knoevenagel condensation/Nazarov cyclization/electrophilic fluorination sequence to afford fluorinated 1-indanone derivatives in moderate to good yields with high diastereoselectivities.
Cui
Han-Feng
HF
Department of Chemistry, Tianjin University, Tianjin, 300072, China.
Dong
Ke-Yan
KY
Zhang
Guang-Wu
GW
Wang
Lian
L
Ma
Jun-An
JA