Endoscopic mucosal resection of Barrett's oesophagus containing dysplasia or intramucosal cancer.
Barrett's oesophagus is premalignant. Oesophagectomy is traditionally regarded as the standard treatment option in the presence of high grade intraepithelial neoplasia or intramucosal cancer. However, oesophagectomy is associated with high rates of mortality and morbidity. Endoscopic ablative therapies are limited by the lack of tissue for histological assessment, and the ablation may be incomplete. Endoscopic mucosal resection is an alternative to surgery in the management of high grade intraepithelial neoplasia and intramucosal cancer. It is less invasive than surgery and, unlike ablative treatments, provides tissue for histological assessment. This review will cover the indications, techniques and results of endoscopic mucosal resection.
Seewald
S
S
Department of Interdisciplinary Endoscopy, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. seewald@uke.uni-hamburg.de
Ang
T L
TL
Soehendra
N
N
D001471:Barrett Esophagus / Q000473:pathology / Q000601:surgery*; D016099:Endoscopy, Gastrointestinal / Q000379:methods*; D004938:Esophageal Neoplasms / Q000473:pathology / Q000601:surgery*; D016629:Esophagectomy / Q000379:methods*; D004947:Esophagus / Q000473:pathology; D006801:Humans; D007413:Intestinal Mucosa / Q000601:surgery; D017075:Laser Coagulation / Q000379:methods; D011230:Precancerous Conditions / Q000601:surgery*