title: Sentinel lymph node biopsy and non-sentinel node involvement in special type breast carcinomas with a good prognosis.
abstract: This study aimed at identifying factors related to sentinel lymph node (SLN) involvement in patients with tubular, cribriform, mucinous or papillary breast carcinoma and those related to non-SLN metastases if an SLN was positive. Multivariate analyses involved logistic and stepwise regressions. The SLNs harboured metastases in 85 of 572 cases, 78 of whom underwent axillary dissection; 19 presented non-SLN positive disease. Lack of lymphovascular invasion, a tumour size < or = 10 mm and a single SLN removed were the factors predicting an SLN metastasis rate <10%, and patients with these features could be candidates for no surgical axillary staging. A positive SLN proportion of < or = 50% and no lymphovascular invasion were associated with a <10% rate of non-SLN invasion; patients with a positive SLN and these features could be candidates for the omission of completion axillary dissection. The opposite presentation of these factors would mandate SLN biopsy and axillary dissection, respectively.
authors.affiliation: Department of Pathology, Bács-Kiskun County Teaching Hospital, Nyiri út 38, H-6000 Kecskemét, Hungary. cserni@freemail.hu
authors.forename: Gábor
authors.initials: G
authors.lastname: Cserni
authors.forename: Simonetta
authors.initials: S
authors.lastname: Bianchi
authors.forename: Vania
authors.initials: V
authors.lastname: Vezzosi
authors.forename: Riccardo
authors.initials: R
authors.lastname: Arisio
authors.forename: Rita
authors.initials: R
authors.lastname: Bori
authors.forename: Johannes L
authors.initials: JL
authors.lastname: Peterse
authors.forename: Anna
authors.initials: A
authors.lastname: Sapino
authors.forename: Maria
authors.initials: M
authors.lastname: Drijkoningen
authors.forename: Janina
authors.initials: J
authors.lastname: Kulka
authors.forename: Vincenzo
authors.initials: V
authors.lastname: Eusebi
authors.forename: Maria Pia
authors.initials: MP
authors.lastname: Foschini
authors.forename: Jean-Pierre
authors.initials: JP
authors.lastname: Bellocq
authors.forename: Cristi
authors.initials: C
authors.lastname: Marin
authors.forename: Sten
authors.initials: S
authors.lastname: Thorstenson
authors.forename: Isabel
authors.initials: I
authors.lastname: Amendoeira
authors.forename: Angelika
authors.initials: A
authors.lastname: Reiner-Concin
authors.forename: Thomas
authors.initials: T
authors.lastname: Decker
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001940:Breast / Q000473:pathology*; D001943:Breast Neoplasms / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008197:Lymph Node Excision / Q000379:methods; D008207:Lymphatic Metastasis; D008875:Middle Aged; D011379:Prognosis; D012044:Regression Analysis; D021701:Sentinel Lymph Node Biopsy / Q000379:methods