Effects of cucurbit[7]uril on enzymatic activity.
The macrocyclic host cucurbit[7]uril exhibits highly specific inhibitory effects on the activity of proteases, which can be analyzed by a host-substrate complexation model.
Hennig
Andreas
A
School of Engineering and Science, Jacobs University Bremen, Campus Ring 1, D-28759, Bremen, Germany.
Ghale
Garima
G
Nau
Werner M
WM
D001952:Bridged-Ring Compounds / Q000737:chemistry* / Q000494:pharmacology*; D007093:Imidazoles / Q000737:chemistry* / Q000494:pharmacology*; D007700:Kinetics; D015394:Molecular Structure; D010447:Peptide Hydrolases / Q000737:chemistry*; D011480:Protease Inhibitors / Q000737:chemistry* / Q000494:pharmacology*; D047028:Macrocyclic Compounds; D000099246:Cucurbit(n)urils
D001952:Bridged-Ring Compounds; D007093:Imidazoles; D010447:Peptide Hydrolases; D011480:Protease Inhibitors; C456276:cucurbit(7)uril; D047028:Macrocyclic Compounds; D000099246:Cucurbit(n)urils