Metabolic syndrome in patients undergoing coronary artery bypass graft: prevalence and a marker of morbidity/mortality during hospitalization and 30 days after hospital discharge.
OBJECTIVE
To compare the morbidity and mortality of patients with and without metabolic syndrome (MS) (according to the First Brazilian Guidelines for Diagnosis and Treatment of MS) undergoing coronary artery bypass graft (CABG) during hospitalization and after 30 days.


METHODS
A total of 107 patients who underwent CABG with no associated procedures were assessed between August and October 2005; 74 (69.2%) of them had MS. Criteria of in-hospital outcome were: acute atrial fibrillation (AF), prolonged mechanical ventilation (MV), need for transfusion of blood products, number of hours spent in the ICU, length of hospital stay (days), respiratory and surgical wound infection, and death. For 30 days, the combination of events such as the need for readmission to hospital, surgical wound infection and death was assessed.


RESULTS
The mean age was 60.6 +/- 9.7 years, and the group with MS presented a higher body mass index and body surface, and a higher prevalence of diabetes. No statistically significant difference was observed in the occurrence of in-hospital events such as AF (15.2% vs. 16.2%), MV (3.0% vs. 2.7%), number of units of blood products used (3.2 +/- 2.7 vs. 2.6 +/- 2.9), length of ICU stay (53.7 +/- 27.3 vs. 58.9 +/- 56.5), length of hospital stay (9.2 +/- 8.7 x 8.5 +/- 8.5), respiratory infection (6.1% vs. 2.7%), surgical wound infection (3.0% vs. 5.4%), and mortality rate (3.0% vs. 0.0%). The occurrence of combined events in 30 days was similar in both groups (12.2% vs. 20.3%, p = NS).


CONCLUSIONS
Patients with MS did not have increased morbidity and mortality when undergoing CABG, however they had a higher trend of occurrence of surgical wound infection.
Pimenta
Eduardo
E
Division of Arterial Hypertension and Nephrology, Instituto Dante Pazzanese de Cardiologia de São Paulo, São Paulo, SP, Brazil. espimenta@cardiol.br
Passarelli
Oswaldo
O
Borelli
Flávio
F
Sousa
Márcio G
MG
Gun
Carlos
C
Amato
Vivian
V
Amodeo
Celso
C
Piegas
Leopoldo Soares
LS
D001026:Coronary Artery Bypass / Q000009:adverse effects / Q000401:mortality*; D005260:Female; D006801:Humans; D007902:Length of Stay; D008297:Male; D024821:Metabolic Syndrome / Q000150:complications* / Q000453:epidemiology; D008875:Middle Aged; D015999:Multivariate Analysis; D015995:Prevalence; D011446:Prospective Studies; D013997:Time Factors