title: The work of the CONRAD task group 5.2: research studies on biokinetic models.
abstract: The objective of this Task Group is the coordination of research studies on biokinetic models and the evaluation of the implications of new biokinetic models on dose assessment and safety standards. For this the new ICRP models, which will be used for a revision of ICRP Publications 30, 54, 68 and 78, are implemented into six different computer codes in five European countries and quality assured by intercomparison procedures. The work has started with the implementation of the new ICRP Alimentary Tract Model. New systemic models and the new NCRP wound model will follow. The work also includes the evaluation of experimental results in terms of formulation by the new model structures and a quality assurance of model formulation.
authors.affiliation: Federal Office for Radiation Protection, Department of Radiation Protection and Health, 85762 Oberschleissheim, Germany. dnosske@bfs.de
authors.forename: D
authors.initials: D
authors.lastname: Nosske
authors.forename: V
authors.initials: V
authors.lastname: Berkovski
authors.forename: A
authors.initials: A
authors.lastname: Birchall
authors.forename: E
authors.initials: E
authors.lastname: Blanchardon
authors.forename: M C
authors.initials: MC
authors.lastname: Cantone
authors.forename: K
authors.initials: K
authors.lastname: Davis
authors.forename: A
authors.initials: A
authors.lastname: Giussani
authors.forename: A
authors.initials: A
authors.lastname: Luciani
authors.forename: J
authors.initials: J
authors.lastname: Marsh
authors.forename: U
authors.initials: U
authors.lastname: Oeh
authors.forename: H
authors.initials: H
authors.lastname: Ratia
authors.forename: M A
authors.initials: MA
authors.lastname: Lopez
mesh_terms: D001822:Body Burden; D003198:Computer Simulation; D005547:Foreign Bodies / Q000150:complications / Q000503:physiopathology*; D006801:Humans; D007700:Kinetics; D008657:Metabolic Clearance Rate; D008954:Models, Biological; D011832:Radiation Injuries / Q000209:etiology / Q000503:physiopathology*; D011868:Radioisotopes / Q000493:pharmacokinetics* / Q000633:toxicity*; D011874:Radiometry / Q000379:methods*; D012062:Relative Biological Effectiveness; D014950:Wounds, Penetrating / Q000209:etiology / Q000503:physiopathology*
chemical_list: D011868:Radioisotopes