Quantification of 1,3-beta-D-glucan levels in children: preliminary data for diagnostic use of the beta-glucan assay in a pediatric setting.
1,3-Beta-D-Glucan serum levels have demonstrated good diagnostic sensitivity and specificity for the diagnosis of candidiasis in adult patients, but normal levels for children have not been established. We found higher 1,3-beta-D-glucan levels in children than those previously reported in adults.
Smith
P Brian
PB
Department of Pediatrics, Division of Pediatric Infectious Diseases, Duke University Medical Center, Durham, North Carolina 27710, USA.
Benjamin
Daniel K
DK
Alexander
Barbara D
BD
Johnson
Melissa D
MD
Finkelman
Malcolm A
MA
Steinbach
William J
WJ
D000293:Adolescent; D000367:Age Factors; D015415:Biomarkers / Q000097:blood*; D002177:Candidiasis / Q000097:blood* / Q000175:diagnosis*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008828:Microbiological Techniques; D012680:Sensitivity and Specificity; D047071:beta-Glucans / Q000097:blood*
D015415:Biomarkers; D047071:beta-Glucans; C033363:beta-1,3-glucan