title: Development of a catalytic aromatic decarboxylation reaction.
abstract: A palladium-catalyzed aromatic decarboxylation reaction has been developed. With electron-rich aromatic acids, the reaction proceeds efficiently under fairly mild conditions in good yields. The method was useful with complex functionalized substrates containing hindered carboxylic acids.
authors.affiliation: Department of Chemistry, Roy and Diana Vagelos Laboratories, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.
authors.forename: Joshua S
authors.initials: JS
authors.lastname: Dickstein
authors.forename: Carol A
authors.initials: CA
authors.lastname: Mulrooney
authors.forename: Erin M
authors.initials: EM
authors.lastname: O'Brien
authors.forename: Barbara J
authors.initials: BJ
authors.lastname: Morgan
authors.forename: Marisa C
authors.initials: MC
authors.lastname: Kozlowski
mesh_terms: D002384:Catalysis; D003653:Decarboxylation; D006841:Hydrocarbons, Aromatic / Q000737:chemistry*; D015394:Molecular Structure; D010165:Palladium / Q000737:chemistry
chemical_list: D006841:Hydrocarbons, Aromatic; D010165:Palladium