A systematic study of carboxylic acids in negative ion mode electrospray ionisation mass spectrometry providing a structural model for ion suppression.
We report a systematic investigation of the effects and structural requirements for ion suppression in negative ion mode electrospray ionisation mass spectrometry of a series of carboxylic acids and present a structural model rationalising ion suppression effects.
Clifford
Mike N
MN
School of Biomedical and Molecular Sciences, The University of Surrey, Guildford, Surrey GU2 7XH, UK.
Lopez
Violeta
V
Poquet
Laure
L
Williamson
Gary
G
Kuhnert
Nikolai
N
D019342:Acetic Acid / Q000737:chemistry; D002264:Carboxylic Acids / Q000032:analysis* / Q000737:chemistry; D007477:Ions; D000432:Methanol / Q000737:chemistry; D015394:Molecular Structure; D012996:Solutions / Q000737:chemistry; D021241:Spectrometry, Mass, Electrospray Ionization / Q000379:methods*; D014867:Water / Q000737:chemistry
D002264:Carboxylic Acids; D007477:Ions; D012996:Solutions; D014867:Water; D019342:Acetic Acid; D000432:Methanol