title: Information about cancer clinical trials: an analysis of Internet resources.
abstract: OBJECTIVE
  Clinical trials are critical to improving patient outcomes, but participation in cancer clinical trials is low. Patient understanding of clinical trial process is also limited. Patients are increasingly using the Internet as a source of information. It is critical that such Internet-based information is relevant, current, balanced, and easy to access and navigate. We critically reviewed seven international online resources that provide information for patients/consumers regarding cancer clinical trials.
  
  
  METHODS
  Seven international websites from North America, Europe and Australia were selected based on profile/usage. Sites were evaluated with respect to their content, readability and appropriateness using a suite of standard assessment tools.
  
  
  RESULTS
  No sites performed well in terms of all assessment criteria. There was substantial variation between sites regarding information provided, content, design and readability. All sites required high literacy levels and assessment using the Standard Assessment of Means tool showed consistent deficiencies.
  
  
  CONCLUSIONS
  Although there are numerous websites providing information about cancer clinical trials to patients/consumers, all evaluated sites have several shortcomings. Attention to the content of information, its presentation and the design of Internet resources has an ethical imperative, and is likely to lead to improved patient satisfaction.
authors.affiliation: Department of Clinical Haematology and Medical Oncology, Royal Melbourne Hospital, Parkville, Victoria, Australia. craig.carden@mh.org.au
authors.forename: Craig P
authors.initials: CP
authors.lastname: Carden
authors.forename: Michael
authors.initials: M
authors.lastname: Jefford
authors.forename: Mark A
authors.initials: MA
authors.lastname: Rosenthal
mesh_terms: D002986:Clinical Trials as Topic; D006801:Humans; D020407:Internet / Q000592:standards*; D008490:Medical Informatics / Q000592:standards*; D009369:Neoplasms / Q000628:therapy*; D010353:Patient Education as Topic / Q000592:standards