Chemical medicine: novel 10-substituted cytisine derivatives with increased selectivity for alpha4beta2 nicotinic acetylcholine receptors.
Kozikowski
Alan P
AP
Drug Discovery Program, Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago, 833 South Wood Street, Chicago, Illinois 60612, USA. kozikowa@uic.edu
Chellappan
Sheela K
SK
Xiao
Yingxian
Y
Bajjuri
Krishna Mohan
KM
Yuan
Hongbin
H
Kellar
Kenneth J
KJ
Petukhov
Pavel A
PA
D000470:Alkaloids / Q000737:chemistry / Q000494:pharmacology*; D001392:Azocines / Q000737:chemistry / Q000494:pharmacology; D001665:Binding Sites; D006801:Humans; D008024:Ligands; D011807:Quinolizines / Q000737:chemistry / Q000494:pharmacology; D011978:Receptors, Nicotinic / Q000737:chemistry / Q000187:drug effects*; D000093843:Quinolizidine Alkaloids
D000470:Alkaloids; D001392:Azocines; D008024:Ligands; D011807:Quinolizines; D011978:Receptors, Nicotinic; C403531:nicotinic receptor alpha4beta2; C004712:cytisine; D000093843:Quinolizidine Alkaloids