Lipid reserve dynamics and magnification of persistent organic pollutants in spawning sockeye salmon (Oncorhynchus nerka) from the Fraser River, British Columbia.
Pacific sockeye salmon (Oncorhynchus nerka) can travel several hundred kilometers to reach native spawning grounds and fulfill semelparous reproduction. The dramatic changes in lipid reserves during upstream migration can greatly affect internal toxicokinetics of persistent organic pollutants (POPs) such as PCBs, PCDDs, and PCDFs. We measured lipid content changes and contaminant concentrations in tissues (liver, muscle, roe/gonads) and biomarker responses (ethoxyresorufin O-deethylase or EROD activity and CYP1A levels) in two Pacific sockeye salmon stocks sampled at several locations along their spawning migration in the Fraser River, British Columbia. Muscle lipid contents declined significantly with increasing upstream migration distance and corresponded to elevated lipid normalized concentrations of PCBs and PCDD/Fs in spawning sockeye. Post-migration magnification factors (MFs) in spawning sockeye ranged between 3 and 12 and were comparable to model-predicted MFs. sigmaPCBs(150-500 ng x g(-1) lipid), sigmaPCDD/Fs (1-1000 pg x g(-1) lipid) and 2,3,7,8-TCDD toxic equivalent or TEQ levels (0.1-15 pg x g(-1) lipid) in spawning sockeye were relatively low and did not affect hepatic EROD activity/CYP1A induction. Despite a 3-fold magnification, TEQ levels in eggs of spawning Fraser River sockeye did not exceed 0.3 pg x g(-1) wet wt, a threshold level associated with 30% egg mortality in salmonids. PCBs in Fraser River sockeye are comparable to previous levels in Pacific sockeye. In contrast to Pacific sockeye from more remote coastal locations, PCDDs and PCDFs in Fraser River sockeye were generally minor components (<25%) of TEQ levels, compared to dioxin like PCB contributions (>75%). The data suggest that (i) the Fraser River is not a major contamination source of PCBs or PCDD/Fs and (ii) marine contaminant distribution, food-chain dynamics, and ocean-migration pathway are likely important factors controlling levels and patterns of POPs in returning Pacific sockeye. We estimate an annual chemical flux entering the Fraser River of up to 150 g for sigmaPCBs and 40 mg for sigmaPCDD/ Fs via returning sockeye. The results indicate that historical concentrations of PCBs and PCDD/Fs remain a potential threat to organism and ecosystem health on the west coast of Canada.
Kelly
Barry C
BC
Contaminant Sciences, Institute of Ocean Sciences, Fisheries and Oceans Canada (DFO), 9860 West Saanich Road, Sidney, British Columbia, Canada.
Gray
Samantha L
SL
Ikonomou
Michael G
MG
Macdonald
J Steve
JS
Bandiera
Stelvio M
SM
Hrycay
Eugene G
EG
D000818:Animals; D001572:Benzofurans / Q000378:metabolism*; D001955:British Columbia; D019363:Cytochrome P-450 CYP1A1 / Q000378:metabolism; D000072338:Dibenzofurans, Polychlorinated; D004784:Environmental Monitoring; D005260:Female; D006066:Gonads / Q000378:metabolism; D008055:Lipids / Q000737:chemistry; D008099:Liver / Q000378:metabolism; D008297:Male; D008862:Microsomes, Liver / Q000201:enzymology; D009132:Muscles / Q000378:metabolism; D010063:Ovum / Q000378:metabolism; D011078:Polychlorinated Biphenyls / Q000378:metabolism*; D000072317:Polychlorinated Dibenzodioxins / Q000031:analogs & derivatives* / Q000378:metabolism; D045483:Rivers; D012474:Salmon / Q000378:metabolism*; D014874:Water Pollutants, Chemical / Q000378:metabolism*
D001572:Benzofurans; D000072338:Dibenzofurans, Polychlorinated; D008055:Lipids; D000072317:Polychlorinated Dibenzodioxins; D014874:Water Pollutants, Chemical; D011078:Polychlorinated Biphenyls; D019363:Cytochrome P-450 CYP1A1