A revised nomenclature for the human and rodent alpha-tubulin gene family.
An essential component of microtubules, alpha-tubulin is also a multigene family in many species. An orthology-based nomenclature for this gene family has previously been difficult to assign due to incomplete genome builds and the high degree of sequence similarity between members of this family. Using the current genome builds, sequence analysis of human, mouse, and rat alpha-tubulin genes has enabled an updated nomenclature to be generated. This revised nomenclature provides a unified language for the discussion of these genes in mammalian species; it has been approved by the gene nomenclature committees of the three species and is supported by researchers in the field.
Khodiyar
Varsha K
VK
HUGO Gene Nomenclature Committee, Department of Biology, University College London, Wolfson House, 4 Stephenson Way, London NW1 2HE, UK. nome@galton.ucl.ac.uk
Maltais
Lois J
LJ
Ruef
Barbara J
BJ
Sneddon
Katherine M B
KM
Smith
Jennifer R
JR
Shimoyama
Mary
M
Cabral
Fernando
F
Dumontet
Charles
C
Dutcher
Susan K
SK
Harvey
Robert J
RJ
Lafanechère
Laurence
L
Murray
John M
JM
Nogales
Eva
E
Piquemal
David
D
Stanchi
Fabio
F
Povey
Sue
S
Lovering
Ruth C
RC
D000818:Animals; D018076:DNA, Complementary / Q000378:metabolism; D006801:Humans; D051379:Mice / Q000235:genetics*; D005810:Multigene Family; D010802:Phylogeny; D051381:Rats / Q000235:genetics*; D009626:Terminology as Topic; D014404:Tubulin / Q000235:genetics*
D018076:DNA, Complementary; D014404:Tubulin