title: Coexisting pseudoxanthoma elasticum and lupus erythematosus: report of two cases.
abstract: Pseudoxanthoma elasticum (PXE) is a heritable connective tissue disorder affecting the elastic structures in the body, manifesting with cutaneous, ophthalmologic and cardiovascular findings. The association of PXE and systemic disease is rare, as only six cases have been reported in the literature. We describe herein two cases of coexisting PXE and cutaneous lupus and discuss a possible association. Although a fortuitous association cannot be excluded, the calculated prevalence of the association in our area was much less than in our observation. Given the ocular and vascular complications of PXE, clinicians who treat patients with lupus should be aware of this possible association.
authors.affiliation: Department of Internal Medicine, Hotel Dieu, Lyon, France.
authors.forename: Julie
authors.initials: J
authors.lastname: Le Scanff
authors.forename: Pascal
authors.initials: P
authors.lastname: Sève
authors.forename: Stephane
authors.initials: S
authors.lastname: Dalle
authors.forename: Laurent
authors.initials: L
authors.lastname: Kodjikian
authors.forename: Luc
authors.initials: L
authors.lastname: Thomas
authors.forename: Christiane
authors.initials: C
authors.lastname: Broussolle
mesh_terms: D000368:Aged; D000793:Angioid Streaks; D004547:Elastic Tissue / Q000473:pathology; D005260:Female; D006801:Humans; D008178:Lupus Erythematosus, Cutaneous / Q000150:complications* / Q000473:pathology; D008179:Lupus Erythematosus, Discoid / Q000150:complications* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D011561:Pseudoxanthoma Elasticum / Q000150:complications* / Q000235:genetics / Q000473:pathology; D012867:Skin / Q000473:pathology*