title: [Serious Staphylococcus aureus skin infections that are Panton-Valentine leukocidin positive: a new challenge].
abstract: The growing emergency of infections with community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) secreting the Panton-Valentine toxin (PVL) has become a serious health problem with epidemic proportions. These bacteria are responsible of severe skin and soft tissue infections, with frequently necrotic lesions, and severe necrotizing pneumonias. CA-MRSA, the spreading of which is particularly observed in certain risk populations (such as schoolchildren, prison inmates, exposure to healthcare establishment) is now also implicated in nosocomial infections. Besides adequate antibiotic treatment, surgical drainage and incision of the skin lesions are important. It is therefore essential to respect elementary hygiene rules in order to prevent the acquisition and transmission of CA-MRSA.
authors.affiliation: Service de dermatologie, HUG, 1211 Genéve 14. gionata.marazza@hcuge.ch
authors.forename: G
authors.initials: G
authors.lastname: Marazza
authors.forename: S
authors.initials: S
authors.lastname: Harbarth
authors.forename: L
authors.initials: L
authors.lastname: Borradori
mesh_terms: D000368:Aged; D001427:Bacterial Toxins / Q000378:metabolism*; D005098:Exotoxins / Q000378:metabolism*; D005260:Female; D006801:Humans; D007956:Leukocidins / Q000378:metabolism*; D008297:Male; D016106:Methicillin Resistance; D008875:Middle Aged; D013203:Staphylococcal Infections / Q000378:metabolism* / Q000628:therapy*; D013211:Staphylococcus aureus
chemical_list: D001427:Bacterial Toxins; D005098:Exotoxins; D007956:Leukocidins; C078284:Panton-Valentine leukocidin