title: Multiple juvenile xanthogranulomas in a 13-year-old.
abstract: A 13-year-old Caucasian girl presented with a 1(1/2) month history of multiple, asymptomatic, discrete, orange-yellow to skin-colored, dome-shaped, smooth, 3 to 6 mm papules on the arms, legs, trunk, and buttock. Pathology showed a dermal infiltrate of Touton-type giant cells, scattered lymphocytes, and macrophages. The patient was diagnosed with juvenile xanthogranuloma. We present this patient because of the uncommon presentation of multiple juvenile xanthogranulomas in a 13-year-old. Although juvenile xanthogranuloma generally occurs in infancy, it must be included in the differential diagnosis for an older child. This entity can less frequently occur in adults and typically a solitary lesion is found. Multiple juvenile xanthogranuloma is rare in older children and adults. Work-up should include a thorough review of systems, physical examination, and ophthalmology examination. Pediatricians and dermatologists should be aware that juvenile xanthogranulomas might occur in older children.
authors.affiliation: Department of Dermatology, College of Medicine, University of Cincinnati, Cincinnati, Ohio, USA.
authors.forename: Kelley Pagliai
authors.initials: KP
authors.lastname: Redbord
authors.forename: Anita P
authors.initials: AP
authors.lastname: Sheth
mesh_terms: D000293:Adolescent; D001706:Biopsy; D005260:Female; D015726:Giant Cells / Q000473:pathology; D006801:Humans; D008214:Lymphocytes / Q000473:pathology; D008264:Macrophages / Q000473:pathology; D012867:Skin / Q000473:pathology; D014972:Xanthogranuloma, Juvenile / Q000473:pathology*