title: Merodrimanes and other constituents from Talaromyces thailandiasis.
abstract: Chemical study of a previously undescribed fungus, Talaromyces thailandiasis, furnished the two new merodrimanes thailandolides A (1) and B (2), an O-methylated derivative (3) of the aromatic fragment incorporated in thailandolide B, and three known closely related 1(3H)-isobenzofuran derivatives, penisimplicissin (4a), vermistatin (4b), and hydroxydihydrovermistatin (4c). Structures were established by spectroscopic measurements and confirmed by X-ray analyses of compounds 1 and 4b. The unusual peptide analogue N-benzoylphenylalanyl-N-benzoylphenyl alaninate (5) isolated earlier from a higher plant was also found.
authors.affiliation: Department of Plant Pathology, Faculty of Agriculture, Kasetsart University, Bangkok, Thailand.
authors.forename: Tida
authors.initials: T
authors.lastname: Dethoup
authors.forename: Leka
authors.initials: L
authors.lastname: Manoch
authors.forename: Anake
authors.initials: A
authors.lastname: Kijjoa
authors.forename: Madalena
authors.initials: M
authors.lastname: Pinto
authors.forename: Luis
authors.initials: L
authors.lastname: Gales
authors.forename: Ana Margarida
authors.initials: AM
authors.lastname: Damas
authors.forename: Artur M S
authors.initials: AM
authors.lastname: Silva
authors.forename: Graham
authors.initials: G
authors.lastname: Eaton
authors.forename: Werner
authors.initials: W
authors.lastname: Herz
mesh_terms: D018360:Crystallography, X-Ray; D008968:Molecular Conformation; D015394:Molecular Structure; D012717:Sesquiterpenes / Q000737:chemistry / Q000302:isolation & purification*; D032901:Talaromyces / Q000737:chemistry*; D013785:Thailand
chemical_list: D012717:Sesquiterpenes; C522150:thailandolide A; C522151:thailandolide B