title: Gender differences in ventricular volumes and left ventricle ejection fraction estimated by myocardial perfusion imaging: comparison of Quantitative Gated SPECT (QGS) and Segami software programs.
abstract: OBJECTIVE
  To test for gender differences in the measurements obtained by Segami and Quantitative Gated SPECT (QGS) software programs.
  
  
  METHODS
  181 asymptomatic individuals without heart disease were submitted to myocardial perfusion imaging. End-diastolic volumes (EDV), end-systolic volumes (ESV) and left ventricular ejection fraction (LVEF) were measured by QGS and Segami software programs to evaluate the influence of gender, age, weight, height, heart rate, systolic blood pressure, diastolic blood pressure, body mass index and body surface area.
  
  
  RESULTS
  The means in the QGS method were: EDV (women= 68 ml; men= 95 ml; p<0.001), LVEF (women= 66.24%; men= 58, 7%) and Segami: EDV (women= 137 ml; men= 174 ml), LVEF (women= 62.67%; men= 58, 52%). There were significant differences between men and women in the EDV (p<0.001), ESV (p<0.001) and LVEF (p=0.001) that persisted after adjusting for body surface area.
  
  
  CONCLUSIONS
  Ventricular volumes were significantly lower and LVEF was significantly higher in women, estimated by QGS or Segami software programs.
authors.affiliation: Instituto do Coração, Hospital das Clínicas, FM, USP, São Paulo, SP, Brazil. alice.yamada@incor.usp.br
authors.forename: Alice Tatsuko
authors.initials: AT
authors.lastname: Yamada
authors.forename: Guilherme de Carvalho
authors.initials: Gde C
authors.lastname: Campos Neto
authors.forename: José
authors.initials: J
authors.lastname: Soares
authors.forename: Maria Clementina P
authors.initials: MC
authors.lastname: Giorgi
authors.forename: Fernando
authors.initials: F
authors.lastname: Araújo
authors.forename: José Claudio
authors.initials: JC
authors.lastname: Meneghetti
authors.forename: Alfredo José
authors.initials: AJ
authors.lastname: Mansur
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000465:Algorithms; D000704:Analysis of Variance; D001830:Body Surface Area; D003430:Cross-Sectional Studies; D005260:Female; D015637:Gated Blood-Pool Imaging / Q000379:methods*; D006352:Heart Ventricles / Q000000981:diagnostic imaging; D006801:Humans; D008297:Male; D008875:Middle Aged; D012737:Sex Factors; D012984:Software; D013318:Stroke Volume; D015899:Tomography, Emission-Computed, Single-Photon / Q000379:methods*; D016277:Ventricular Function, Left / Q000502:physiology*