title: Dehydroepiandrosterone behavior and lipid profile in non-obese women undergoing abdominoplasty.
abstract: BACKGROUND
  The aim of this study was to determine any change in dehydroepiandrosterone (DHEA) and lipid profile in non-obese women after abdominoplasty.
  
  
  METHODS
  An auto-controlled clinical trial was carried out. 9 women aged 35 to 40 years with BMI 22-25 kg/m2 were studied. Basal lipid profile and DHEA were performed and repeated 1 month postoperatively. Statistical analysis used Wilcoxon signed-ranks test (two-tailed).
  
  
  RESULTS
  Weight of resected specimen was 606.11 +/- 143.4 grams. No significant changes were observed in high-density cholesterol (48.0 +/- 9.6 vs 48.8 +/- 11.0 mg/dl; P=0.106) or in triglycerides (119.2 +/- 50.9 vs 148.4 +/- 45.8 mg/dl; P = 0.139). Significant increases were obtained in DHEA (3.69 +/- 3.05 vs 11.09 +/- 6.3 ng/ml; P<0.008), low-density cholesterol (LDL) (87.4 +/- 23.5 vs 108.5 +/- 28.3 mg/dl; P<0.008 and total cholesterol (155.1 +/- 30.6 vs 186.6 +/- 33.1 mg/dl; P<0.008).
  
  
  CONCLUSIONS
  Excision of subcutaneous abdominal fat in studies 1 month later increased DHEA, whose role is controversial in visceral fat distribution, and increased LDL cholesterol and total cholesterol, both risk markers for cardiovascular illness.
authors.affiliation: Medical Research Unit in Clinical Epidemiology, Medical Unit of High Specialty, Mexican Institute of Social Security, Guadalajara, Mexico. durun@megared.net.mx
authors.forename: José Antonio
authors.initials: JA
authors.lastname: Robles-Cervantes
authors.forename: Manuel
authors.initials: M
authors.lastname: Espaillat-Pavonessa
authors.forename: Lázaro
authors.initials: L
authors.lastname: Cárdenas-Camarena
authors.forename: Esperanza
authors.initials: E
authors.lastname: Martínez-Abundis
authors.forename: Manuel
authors.initials: M
authors.lastname: González-Ortiz
mesh_terms: D050153:Abdominal Fat / Q000601:surgery*; D000328:Adult; D008076:Cholesterol, HDL / Q000097:blood; D008078:Cholesterol, LDL / Q000097:blood; D003687:Dehydroepiandrosterone / Q000097:blood*; D005260:Female; D006801:Humans; D015187:Lipectomy; D008055:Lipids / Q000097:blood*; D011184:Postoperative Period; D014280:Triglycerides / Q000097:blood
chemical_list: D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D008055:Lipids; D014280:Triglycerides; D003687:Dehydroepiandrosterone