title: Nucleophilic aromatic substitution using Et3SiH/cat. t-Bu-P4 as a system for nucleophile activation.
abstract: A novel type of deprotonative arylation of nucleophiles was conducted using Et(3)SiH/cat. t-Bu-P4 and the powerful S(N)Ar reactions of aryl fluorides were accomplished using alcohols and malonates as nucleophiles.
authors.affiliation: Graduate School of Pharmaceutical Sciences, Tohoku University, Aramaki Aza Aoba 6-3, Sendai, 980-8578, Japan.
authors.forename: Masahiro
authors.initials: M
authors.lastname: Ueno
authors.forename: Misato
authors.initials: M
authors.lastname: Yonemoto
authors.forename: Masahiro
authors.initials: M
authors.lastname: Hashimoto
authors.forename: Andrew E H
authors.initials: AE
authors.lastname: Wheatley
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Naka
authors.forename: Yoshinori
authors.initials: Y
authors.lastname: Kondo
mesh_terms: D000438:Alcohols / Q000737:chemistry; D002073:Butanes / Q000737:chemistry*; D002384:Catalysis; D006841:Hydrocarbons, Aromatic / Q000737:chemistry*; D006845:Hydrocarbons, Fluorinated / Q000737:chemistry*; D008314:Malonates / Q000737:chemistry; D008956:Models, Chemical; D009943:Organophosphorus Compounds / Q000737:chemistry*; D011522:Protons; D012821:Silanes / Q000737:chemistry*
chemical_list: D000438:Alcohols; D002073:Butanes; D006841:Hydrocarbons, Aromatic; D006845:Hydrocarbons, Fluorinated; D008314:Malonates; D009943:Organophosphorus Compounds; D011522:Protons; D012821:Silanes; C521797:tert-butyl-P4; C512918:triethylsilane