Brooke-Spiegler syndrome - report of four families: treatment with CO2 laser.
BACKGROUND
Brooke-Spiegler syndrome is a well known but rare cutaneous disorder characterized by the presence of multiple trichoepitheliomas and cylindromas.


METHODS
Four families with Brooke-Spiegler syndrome are described.


RESULTS
Spiradenomas developed on the back in two patients. A CO(2) laser was used to treat facial trichoepitheliomas in two patients with good results.


CONCLUSIONS
The large number of facial lesions in this syndrome often produce a significant emotional impact. We believe that it is important to provide patients with a good therapeutic option. CO(2) laser therapy may fill this role.
Retamar
Roberto Adrián
RA
Department of Dermatology, Hospital Cosme Argerich and CHOUELA DERMATOLOGIA Center, Buenos Aires, Argentina. aretamar@intramed.net.ar
Stengel
F
F
Saadi
M E
ME
Kien
M C
MC
Della Giovana
P
P
Cabrera
H
H
Chouela
E N
EN
D006607:Adenoma, Sweat Gland / Q000473:pathology / Q000601:surgery*; D000328:Adult; D000368:Aged; D003528:Carcinoma, Adenoid Cystic / Q000473:pathology / Q000601:surgery*; D002648:Child; D005145:Face / Q000473:pathology; D005260:Female; D006801:Humans; D053685:Laser Therapy; D008297:Male; D008875:Middle Aged; D018294:Neoplasms, Adnexal and Skin Appendage / Q000473:pathology / Q000601:surgery*; D009378:Neoplasms, Multiple Primary / Q000473:pathology / Q000601:surgery*; D009386:Neoplastic Syndromes, Hereditary / Q000473:pathology / Q000601:surgery*; D012535:Scalp / Q000473:pathology; D012878:Skin Neoplasms / Q000473:pathology / Q000601:surgery*