title: Time trends in the incidence of peptic ulcers and oesophagitis between 1994 and 2003.
abstract: This study examined time trends in the incidence of peptic ulcers and oesophagitis, and the prescription of acid-inhibiting drugs in the period 1994-2003. Data were retrieved from records in general practices in Flanders, Belgium. The incidence of duodenal ulcers decreased by two-thirds and the incidence of gastric ulcers halved, the incidence of oesophagitis initially increased and decreased slowly later on. In 10 years the proportion of patients taking proton-pump inhibitors rose sixfold while the proportion taking H(2) antagonists remained stable.
authors.affiliation: Department of General Practice, Katholieke Universiteit Leuven, Belgium. bartholomeeusen.stefaan@med.kuleuven.be
authors.forename: Stefaan
authors.initials: S
authors.lastname: Bartholomeeusen
authors.forename: Jan
authors.initials: J
authors.lastname: Vandenbroucke
authors.forename: Carla
authors.initials: C
authors.lastname: Truyers
authors.forename: Carl
authors.initials: C
authors.lastname: Truyers
authors.forename: Frank
authors.initials: F
authors.lastname: Buntinx
mesh_terms: D000328:Adult; D000368:Aged; D000897:Anti-Ulcer Agents / Q000627:therapeutic use*; D001530:Belgium / Q000453:epidemiology; D004941:Esophagitis / Q000188:drug therapy / Q000453:epidemiology*; D006801:Humans; D015994:Incidence; D008875:Middle Aged; D010437:Peptic Ulcer / Q000188:drug therapy / Q000453:epidemiology*; D054328:Proton Pump Inhibitors; D013997:Time Factors
chemical_list: D000897:Anti-Ulcer Agents; D054328:Proton Pump Inhibitors