title: Genital porokeratosis: treatment with diclofenac topical gel.
abstract: Genital porokeratosis (PK) is a rare and probably underestimated subset of PK that mostly affects middle-aged men. As in other clinical variants of PK, management can be difficult. Surgery and CO(2) laser vaporization may be efficient on individual lesions but topical treatment can be considered when the elements are more scattered and/or more numerous. We report the case of a 68-year-old man with a disseminated PK following a 20-year history of lesions restricted to the genitalia for whom 3% diclofenac gel succeeded in stabilizing their evolution and achieving symptomatic relief. In conclusion, topical diclofenac could be worth considering in the management of genital PK with numerous lesions.
authors.affiliation: University of Montpellier I, Department of Dermatology, Hôpital Saint-Eloi, Montpellier, France.
authors.forename: Nicolas
authors.initials: N
authors.lastname: Kluger
authors.forename: Olivier
authors.initials: O
authors.lastname: Dereure
authors.forename: Jean-Jacques
authors.initials: JJ
authors.lastname: Guilhou
authors.forename: Bernard
authors.initials: B
authors.lastname: Guillot
mesh_terms: D000279:Administration, Cutaneous; D000368:Aged; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage / Q000627:therapeutic use*; D003937:Diagnosis, Differential; D004008:Diclofenac / Q000008:administration & dosage / Q000627:therapeutic use*; D005782:Gels; D006801:Humans; D008297:Male; D017499:Porokeratosis / Q000175:diagnosis* / Q000188:drug therapy* / Q000473:pathology; D012611:Scrotum / Q000473:pathology*
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D005782:Gels; D004008:Diclofenac