title: Transoral laser microsurgery for carcinoma of the supraglottic larynx.
abstract: OBJECTIVE
  The study goal was to report the oncologic outcomes of transoral laser microsurgery (TLM) in the treatment of squamous cell carcinoma of the supraglottic larynx.
  
  
  METHODS
  A two-center prospective case series analysis.
  
  
  RESULTS
  Thirty-eight patients underwent TLM for previously untreated carcinoma of the supraglottic larynx between 1997 and 2005. Pathological T stages were T1 in 8 (21%), T2 in 14 (37%), T3 in 8 (21%), and T4 in 8 (21%). Twenty-six patients (68%) had neck dissections. Thirteen patients (34%) received adjuvant radiotherapy. The mean follow-up for all patients was 31 months. The 2-year Kaplan-Meier estimates for local control were 97%; locoregional control, 94%; disease-specific survival, 80%; and overall survival, 85%. The overall functional laryngeal preservation rate was 79% (19 of 24).
  
  
  CONCLUSIONS
  TLM is a safe and effective treatment for cancer of the supraglottic larynx.
  
  
  CONCLUSIONS
  TLM is an emerging strategy in the management of laryngeal cancer.
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, Mayo Clinic, Jacksonville, FL 32224, USA. grant.david@mayo.edu
authors.forename: David G
authors.initials: DG
authors.lastname: Grant
authors.forename: John R
authors.initials: JR
authors.lastname: Salassa
authors.forename: Michael L
authors.initials: ML
authors.lastname: Hinni
authors.forename: Bruce W
authors.initials: BW
authors.lastname: Pearson
authors.forename: Richard E
authors.initials: RE
authors.lastname: Hayden
authors.forename: William C
authors.initials: WC
authors.lastname: Perry
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002294:Carcinoma, Squamous Cell / Q000473:pathology / Q000601:surgery*; D018450:Disease Progression; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007822:Laryngeal Neoplasms / Q000473:pathology / Q000601:surgery*; D007828:Laryngoscopy / Q000379:methods*; D053685:Laser Therapy / Q000379:methods*; D008297:Male; D008866:Microsurgery / Q000379:methods*; D008875:Middle Aged; D037981:Neck Dissection; D009367:Neoplasm Staging; D011446:Prospective Studies