title: Occurrence of both bladder and prostate cancer in five cancer registries in Belgium, The Netherlands and the United Kingdom.
abstract: OBJECTIVE
  To assess the occurrence of both bladder and prostate tumours in five well defined cancer registries.
  
  
  METHODS
  Anonymous data were provided from each cancer registry on all male bladder and prostate cancers (invasive and non-invasive). Poisson regression was used to model the rate of developing the second primary tumour and generated incidence rate ratios (RRs) with 95% confidence intervals.
  
  
  RESULTS
  For bladder cancer and prostate cancer as first diagnosis, there was an excess risk to develop the second neoplasm. The RR decreased with increasing age of the patients. No effect of the initial treatment of the first neoplasm was found.
  
  
  CONCLUSIONS
  This analysis found an excess risk to develop prostate cancer in bladder cancer patients younger than 70 years and the first year of follow-up after the diagnosis of bladder cancer. This may be due to detection bias, although a common aetiology may also be present.
authors.affiliation: Department of General Practice, Katholieke Universiteit Leuven - Comprehensive Cancer Institute Limburg, Belgium. Eliane.Kellen@med.kuleuven.be
authors.forename: Eliane
authors.initials: E
authors.lastname: Kellen
authors.forename: Maurice P
authors.initials: MP
authors.lastname: Zeegers
authors.forename: Miranda
authors.initials: M
authors.lastname: Dirx
authors.forename: Saskia
authors.initials: S
authors.lastname: Houterman
authors.forename: Jos
authors.initials: J
authors.lastname: Droste
authors.forename: Gill
authors.initials: G
authors.lastname: Lawrence
authors.forename: Carla
authors.initials: C
authors.lastname: Truyers
authors.forename: Liesbeth
authors.initials: L
authors.lastname: Bruckers
authors.forename: Geert
authors.initials: G
authors.lastname: Molenberghs
authors.forename: Steven
authors.initials: S
authors.lastname: Joniau
authors.forename: Frank
authors.initials: F
authors.lastname: Buntinx
mesh_terms: D000328:Adult; D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D001530:Belgium / Q000453:epidemiology; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D016609:Neoplasms, Second Primary / Q000453:epidemiology* / Q000628:therapy; D009426:Netherlands / Q000453:epidemiology; D011471:Prostatic Neoplasms / Q000453:epidemiology* / Q000628:therapy; D012042:Registries; D012307:Risk Factors; D006113:United Kingdom / Q000453:epidemiology; D001749:Urinary Bladder Neoplasms / Q000453:epidemiology* / Q000628:therapy