title: In vitro susceptibility to posaconazole of 1,903 yeast isolates recovered in France from 2003 to 2006 and tested by the method of the European committee on antimicrobial susceptibility testing.
abstract: The posaconazole MIC(90) for 1,903 yeast isolates from France was 1 microg/ml (range, < or =0.015 to 8 microg/ml). Ninety percent of isolates with fluconazole MICs of > or =8 microg/ml (n = 509) and 90% of those with voriconazole MICs of > or =2 microg/ml (n = 80) were inhibited by 2 and 8 microg/ml of posaconazole, respectively.
authors.affiliation: Centre National de Référence Mycologie et Antifongiques, Unité de Mycologie Moléculaire, CNRS URA3012, Institut Pasteur, 25 rue du Dr. Roux, 75724 Paris Cedex 15, France. olortho@pasteur.fr
authors.forename: Olivier
authors.initials: O
authors.lastname: Lortholary
authors.forename: Eric
authors.initials: E
authors.lastname: Dannaoui
authors.forename: Dorothée
authors.initials: D
authors.lastname: Raoux
authors.forename: Damien
authors.initials: D
authors.lastname: Hoinard
authors.forename: Annick
authors.initials: A
authors.lastname: Datry
authors.forename: André
authors.initials: A
authors.lastname: Paugam
authors.forename: Jean-Louis
authors.initials: JL
authors.lastname: Poirot
authors.forename: Claire
authors.initials: C
authors.lastname: Lacroix
authors.forename: Françoise
authors.initials: F
authors.lastname: Dromer
mesh_terms: D000935:Antifungal Agents / Q000494:pharmacology*; D015725:Fluconazole / Q000494:pharmacology; D005602:France / Q000453:epidemiology; D006801:Humans; D008826:Microbial Sensitivity Tests; D009181:Mycoses / Q000453:epidemiology* / Q000235:genetics*; D011743:Pyrimidines / Q000494:pharmacology; D014230:Triazoles / Q000494:pharmacology*; D065819:Voriconazole; D015003:Yeasts / Q000187:drug effects*
chemical_list: D000935:Antifungal Agents; D011743:Pyrimidines; D014230:Triazoles; C101425:posaconazole; D015725:Fluconazole; D065819:Voriconazole