title: [Two cases of renal cell carcinoma with diabetes mellitus that was healed after nephrectomy].
abstract: Two cases of renal cell carcinoma presenting with uncontrolled diabetes mellitus are reported. A 61 and 64-year-old women with hyperglycemia were incidentally found to have a right renal tumor. Laboratory investigation of both cases revealed glucose of 324 mg/dl and 357 mg/dl, HbAlc of 9.3% and 8.9%, respectively. Hyperglycemia had been controlled by administration of 25 and 58 units of insulin, respectively. In both cases, after a radical nephrectomy, the diabetic state completely resolved without insulin administration. Immunohistological study revealed the tumor cells positive in one case and negative in the other case for interleukin (IL) 6.
authors.affiliation: The Department of Urology, Chigasaki Municipal Hospital.
authors.forename: Yasushi
authors.initials: Y
authors.lastname: Yumura
authors.forename: Yuzo
authors.initials: Y
authors.lastname: Yamashita
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Senga
authors.forename: Shinichiro
authors.initials: S
authors.lastname: Jinza
authors.forename: Akihiko
authors.initials: A
authors.lastname: Goro
mesh_terms: D002292:Carcinoma, Renal Cell / Q000000981:diagnostic imaging / Q000601:surgery*; D048909:Diabetes Complications / Q000503:physiopathology*; D003924:Diabetes Mellitus, Type 2 / Q000503:physiopathology; D005260:Female; D006801:Humans; D007680:Kidney Neoplasms / Q000000981:diagnostic imaging / Q000601:surgery*; D008875:Middle Aged; D009392:Nephrectomy; D012074:Remission Induction; D014057:Tomography, X-Ray Computed