Fabrication of a novel temperature sensitive poly(N-isopropyl-3-butenamide) hydrogel.
To investigate the temperature sensitive mechanism and develop temperature sensitive materials, a novel poly(N-isopropyl-3-butenamide) (PNIPBAm) hydrogel was designed and synthesized. The maximum swelling ratio, temperature dependence of swelling ratio and deswelling/reswelling kinetics of the resulted PNIPBAm hydrogel were characterized. The data obtained exhibited that the temperature sensitivity of the PNIPBAm hydrogel depended on the amount of crosslinker, i.e. the temperature sensitivity decreased with the increasing content of crosslinker. This novel temperature sensitive hydrogel would have the potential applications in bioengineering and biotechnology fields.
Xu
Xiao-Ding
XD
Key Laboratory of Biomedical Polymers of Ministry of Education & Department of Chemistry, Wuhan University, Wuhan 430072, PR China.
Zhang
Xian-Zheng
XZ
Wang
Bo
B
Cheng
Si-Xue
SX
Zhuo
Ren-Xi
RX
Wang
Zong-Chun
ZC
D000178:Acrylamides / Q000737:chemistry; D000180:Acrylic Resins; D000577:Amides / Q000737:chemistry*; D002087:Butyrates / Q000737:chemistry; D020100:Hydrogels / Q000138:chemical synthesis* / Q000737:chemistry; D006885:Hydroxybutyrates / Q000737:chemistry; D011108:Polymers / Q000138:chemical synthesis* / Q000737:chemistry; D013696:Temperature
D000178:Acrylamides; D000180:Acrylic Resins; D000577:Amides; D002087:Butyrates; D020100:Hydrogels; D006885:Hydroxybutyrates; D011108:Polymers; C052970:poly-N-isopropylacrylamide; C479121:3-butenoic acid; C002574:dopastin