title: Iatrogenic seeding of a giant cell tumor of the patella to the proximal tibia.
abstract: Iatrogenic transplantation of tumor is a rare but avoidable complication, often resulting in additional morbidity or even mortality. We present a case of a 22-year-old woman with a giant cell tumor of the patella initially treated by curettage and bone grafting from the ipsilateral proximal tibia. Local recurrence and tumor growth in the proximal tibia required extensive surgeries. We will discuss the risk of iatrogenic metastasis by direct implantation, often attributable to inadequate surgical planning or poor surgical techniques. The cause and prevention of implantation metastasis are discussed and the basic principles of musculoskeletal tumor management emphasized.
authors.affiliation: Department of Orthopedics, Lutfi Kirdar Research Hospital, Istanbul, Turkey. oofluoglu@gmail.com
authors.forename: Onder
authors.initials: O
authors.lastname: Ofluoglu
authors.forename: Rakesh
authors.initials: R
authors.lastname: Donthineni
mesh_terms: D000328:Adult; D019645:Arthroplasty, Replacement, Knee; D001859:Bone Neoplasms / Q000556:secondary / Q000601:surgery*; D016025:Bone Transplantation / Q000009:adverse effects*; D002983:Clinical Competence; D003475:Curettage / Q000009:adverse effects; D005260:Female; D018212:Giant Cell Tumor of Bone / Q000473:pathology / Q000556:secondary / Q000601:surgery*; D006801:Humans; D007049:Iatrogenic Disease / Q000517:prevention & control; D008279:Magnetic Resonance Imaging; D009364:Neoplasm Recurrence, Local / Q000473:pathology* / Q000601:surgery; D009366:Neoplasm Seeding; D010329:Patella / Q000473:pathology / Q000503:physiopathology / Q000601:surgery*; D020127:Recovery of Function; D013977:Tibia / Q000473:pathology / Q000503:physiopathology / Q000637:transplantation*; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome