Membrane protein structure: prediction versus reality.
Since high-resolution structural data are still scarce, different kinds of theoretical structure prediction algorithms are of major importance in membrane protein biochemistry. But how well do the current prediction methods perform? Which structural features can be predicted and which cannot? And what can we expect in the next few years?
Elofsson
Arne
A
Center for Biomembrane Research, Stockholm Bioinformatics Center, Department of Biochemistry and Biophysics, Stockholm University, SE-106 91 Stockholm, Sweden. arne@bioinfo.se
von Heijne
Gunnar
G
D000465:Algorithms; D000595:Amino Acid Sequence; D019295:Computational Biology; D008565:Membrane Proteins / Q000737:chemistry* / Q000145:classification / Q000235:genetics / Q000378:metabolism*; D008958:Models, Molecular; D008969:Molecular Sequence Data; D011485:Protein Binding; D011487:Protein Conformation; D017510:Protein Folding
D008565:Membrane Proteins