Synthesis and characterisation of core-shell structures for orthopaedic surgery.
This paperwork deals with the obtaining and characterisation of new acrylic cements for bone surgery. The final mixture of cement contains derivatives of methacryloyloxyethyl phosphate, methacrylic acid or 2-acrylamido-2-methyl-1-propane sulphonic acid. The idea of using these monomers is sustained by their ability to form ionic bonds with barium, which is responsible for X-ray reflection and by the biocompatibility of these structures. The strategy consists in the obtaining of core-shell structures through heterogeneous polymerisation, which are used for final cement's manufacture. The orthopaedic cements were characterised by SEM, EDX, compression resistance and cytotoxicity assays.
Rusen
Edina
E
Department of Macromolecular Compounds, University Politehnica of Bucharest, 010072 Bucharest, Romania.
Zaharia
Cătălin
C
Zecheru
Teodora
T
Mărculescu
Bogdan
B
Filmon
Robert
R
Chappard
Daniel
D
Bădulescu
Roxana
R
Cincu
Corneliu
C
D000180:Acrylic Resins; D000818:Animals; D002460:Cell Line; D002470:Cell Survival / Q000187:drug effects; D008689:Methacrylates / Q000737:chemistry / Q000633:toxicity; D051379:Mice; D008855:Microscopy, Electron, Scanning; D015394:Molecular Structure; D009985:Orthopedics / Q000379:methods*; D013314:Stress, Mechanical
D000180:Acrylic Resins; D008689:Methacrylates; C026575:2-hydroxyethyl methacrylate phosphate