[Detection of fungal metabolites showing toxic activity through Artemia salina bioassay].
The aim of this study was to detect toxic metabolites from fungi contaminating food and medicinal herbs by applying the toxicity assay to Artemia salina. According to toxicity percentages, the extracts were classified as nontoxic (NT), slightly toxic (ST), toxic (T) and highly toxic (HT). Those classified as T and HT were assayed for mycotoxins. Only 6 out of 71 strains were found to be T (8.5%) for A. salina. Penicillium brevicompactum Dierckx, isolated from sausages, was found to be HT, mainly due to the presence of ochratoxin A and two other unidentified metabolites.
González
Ana María
AM
Cátedra de Microbiología General, Facultad de Bioquímica y Ciencias Biológicas. Universidad Nacional del Litoral, Ciudad Universitaria, Paraje El Pozo, Santa Fe, Argentina. amgpodio@fbcb.unl.edu.ar
Presa
Maximiliano
M
Latorre
María Gabriela
MG
Lurá
María Cristina
MC
D000818:Animals; D001156:Artemia / Q000187:drug effects*; D031175:Baccharis / Q000382:microbiology; D001681:Biological Assay / Q000379:methods*; D004340:Drug Contamination; D005504:Food Analysis / Q000379:methods; D005506:Food Contamination; D005516:Food Microbiology; D005658:Fungi / Q000302:isolation & purification* / Q000378:metabolism; D030019:Ilex paraguariensis / Q000382:microbiology; D032411:Lippia / Q000382:microbiology; D028501:Malva / Q000382:microbiology; D008461:Meat Products / Q000382:microbiology; D036142:Mentha piperita / Q000382:microbiology; D003904:Mitosporic Fungi / Q000302:isolation & purification / Q000378:metabolism; D009183:Mycotoxins / Q000032:analysis* / Q000494:pharmacology; D010946:Plants, Medicinal / Q000382:microbiology*; D013025:Glycine max / Q000382:microbiology; D014116:Toxicology / Q000379:methods*; D003313:Zea mays / Q000382:microbiology
D009183:Mycotoxins