title: LongSAGE profiling of nine human embryonic stem cell lines.
abstract: To facilitate discovery of novel human embryonic stem cell (ESC) transcripts, we generated 2.5 million LongSAGE tags from 9 human ESC lines. Analysis of this data revealed that ESCs express proportionately more RNA binding proteins compared with terminally differentiated cells, and identified novel ESC transcripts, at least one of which may represent a marker of the pluripotent state.
authors.affiliation: Genome Sciences Centre, British Columbia Cancer Agency, Vancouver, British Columbia, Canada, V5Z 1L3.
authors.forename: Martin
authors.initials: M
authors.lastname: Hirst
authors.forename: Allen
authors.initials: A
authors.lastname: Delaney
authors.forename: Sean A
authors.initials: SA
authors.lastname: Rogers
authors.forename: Angelique
authors.initials: A
authors.lastname: Schnerch
authors.forename: Deryck R
authors.initials: DR
authors.lastname: Persaud
authors.forename: Michael D
authors.initials: MD
authors.lastname: O'Connor
authors.forename: Thomas
authors.initials: T
authors.lastname: Zeng
authors.forename: Michelle
authors.initials: M
authors.lastname: Moksa
authors.forename: Keith
authors.initials: K
authors.lastname: Fichter
authors.forename: Diana
authors.initials: D
authors.lastname: Mah
authors.forename: Anne
authors.initials: A
authors.lastname: Go
authors.forename: Ryan D
authors.initials: RD
authors.lastname: Morin
authors.forename: Agnes
authors.initials: A
authors.lastname: Baross
authors.forename: Yongjun
authors.initials: Y
authors.lastname: Zhao
authors.forename: Jaswinder
authors.initials: J
authors.lastname: Khattra
authors.forename: Anna-Liisa
authors.initials: AL
authors.lastname: Prabhu
authors.forename: Pawan
authors.initials: P
authors.lastname: Pandoh
authors.forename: Helen
authors.initials: H
authors.lastname: McDonald
authors.forename: Jennifer
authors.initials: J
authors.lastname: Asano
authors.forename: Noreen
authors.initials: N
authors.lastname: Dhalla
authors.forename: Kevin
authors.initials: K
authors.lastname: Ma
authors.forename: Stephanie
authors.initials: S
authors.lastname: Lee
authors.forename: Adrian
authors.initials: A
authors.lastname: Ally
authors.forename: Neil
authors.initials: N
authors.lastname: Chahal
authors.forename: Stephanie
authors.initials: S
authors.lastname: Menzies
authors.forename: Asim
authors.initials: A
authors.lastname: Siddiqui
authors.forename: Robert
authors.initials: R
authors.lastname: Holt
authors.forename: Steven
authors.initials: S
authors.lastname: Jones
authors.forename: Daniela S
authors.initials: DS
authors.lastname: Gerhard
authors.forename: James A
authors.initials: JA
authors.lastname: Thomson
authors.forename: Connie J
authors.initials: CJ
authors.lastname: Eaves
authors.forename: Marco A
authors.initials: MA
authors.lastname: Marra
mesh_terms: D001483:Base Sequence; D002460:Cell Line; D053595:Embryonic Stem Cells / Q000378:metabolism*; D020869:Gene Expression Profiling; D006801:Humans; D039904:Pluripotent Stem Cells / Q000378:metabolism*; D016601:RNA-Binding Proteins / Q000235:genetics; D016415:Sequence Alignment
chemical_list: D016601:RNA-Binding Proteins