LongSAGE profiling of nine human embryonic stem cell lines.
To facilitate discovery of novel human embryonic stem cell (ESC) transcripts, we generated 2.5 million LongSAGE tags from 9 human ESC lines. Analysis of this data revealed that ESCs express proportionately more RNA binding proteins compared with terminally differentiated cells, and identified novel ESC transcripts, at least one of which may represent a marker of the pluripotent state.
Hirst
Martin
M
Genome Sciences Centre, British Columbia Cancer Agency, Vancouver, British Columbia, Canada, V5Z 1L3.
Delaney
Allen
A
Rogers
Sean A
SA
Schnerch
Angelique
A
Persaud
Deryck R
DR
O'Connor
Michael D
MD
Zeng
Thomas
T
Moksa
Michelle
M
Fichter
Keith
K
Mah
Diana
D
Go
Anne
A
Morin
Ryan D
RD
Baross
Agnes
A
Zhao
Yongjun
Y
Khattra
Jaswinder
J
Prabhu
Anna-Liisa
AL
Pandoh
Pawan
P
McDonald
Helen
H
Asano
Jennifer
J
Dhalla
Noreen
N
Ma
Kevin
K
Lee
Stephanie
S
Ally
Adrian
A
Chahal
Neil
N
Menzies
Stephanie
S
Siddiqui
Asim
A
Holt
Robert
R
Jones
Steven
S
Gerhard
Daniela S
DS
Thomson
James A
JA
Eaves
Connie J
CJ
Marra
Marco A
MA
D001483:Base Sequence; D002460:Cell Line; D053595:Embryonic Stem Cells / Q000378:metabolism*; D020869:Gene Expression Profiling; D006801:Humans; D039904:Pluripotent Stem Cells / Q000378:metabolism*; D016601:RNA-Binding Proteins / Q000235:genetics; D016415:Sequence Alignment
D016601:RNA-Binding Proteins