Electrolyte changes during craniotomy caused by administration of hypertonic mannitol.
We report a 31-year-old woman scheduled for a right frontal craniotomy and debulking of a recurrent grade 3 astrocytoma. Mannitol was given at the request of the surgeons. Peaked T waves were noted on electrocardiography, and electrolyte analysis showed hyperkalemia and hyponatremia.
Hassan
Zaki-Udin
ZU
Department of Anesthesiology, University of Kentucky School of Medicine, Lexington, KY, USA.
Kruer
Justin J
JJ
Fuhrman
Thomas M
TM
D000328:Adult; D001254:Astrocytoma / Q000601:surgery; D001932:Brain Neoplasms / Q000601:surgery; D003399:Craniotomy; D004562:Electrocardiography; D005260:Female; D006801:Humans; D006947:Hyperkalemia / Q000139:chemically induced*; D006982:Hypertonic Solutions / Q000009:adverse effects*; D007010:Hyponatremia / Q000139:chemically induced*; D007431:Intraoperative Complications / Q000139:chemically induced*; D008353:Mannitol / Q000009:adverse effects*
D006982:Hypertonic Solutions; D008353:Mannitol