title: Missing the bull's eye.
abstract: We report a patient with a long history of hydroxychloroquine use. Clinical examinations had been performed according to American Academy of Ophthalmology guidelines with no abnormalities. A multifocal electroretinogram (mfERG) was performed to further assess macular function. Multifocal ERG may detect macular dysfunction earlier than the currently recommended screening guidelines in patients with potential for macular toxicity from hydroxychloroquine.
authors.affiliation: Neuro-ophthalmology Service, Wills Eye Institute, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA.
authors.forename: Molly E
authors.initials: ME
authors.lastname: Gilbert
authors.forename: Peter J
authors.initials: PJ
authors.lastname: Savino
mesh_terms: D018501:Antirheumatic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D001172:Arthritis, Rheumatoid / Q000188:drug therapy*; D004596:Electroretinography; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006886:Hydroxychloroquine / Q000009:adverse effects* / Q000627:therapeutic use; D008266:Macula Lutea; D008875:Middle Aged; D012164:Retinal Diseases / Q000139:chemically induced* / Q000175:diagnosis / Q000503:physiopathology; D012307:Risk Factors; D013997:Time Factors
chemical_list: D018501:Antirheumatic Agents; D006886:Hydroxychloroquine