title: Fabrication of a novel temperature sensitive poly(N-isopropyl-3-butenamide) hydrogel.
abstract: To investigate the temperature sensitive mechanism and develop temperature sensitive materials, a novel poly(N-isopropyl-3-butenamide) (PNIPBAm) hydrogel was designed and synthesized. The maximum swelling ratio, temperature dependence of swelling ratio and deswelling/reswelling kinetics of the resulted PNIPBAm hydrogel were characterized. The data obtained exhibited that the temperature sensitivity of the PNIPBAm hydrogel depended on the amount of crosslinker, i.e. the temperature sensitivity decreased with the increasing content of crosslinker. This novel temperature sensitive hydrogel would have the potential applications in bioengineering and biotechnology fields.
authors.affiliation: Key Laboratory of Biomedical Polymers of Ministry of Education & Department of Chemistry, Wuhan University, Wuhan 430072, PR China.
authors.forename: Xiao-Ding
authors.initials: XD
authors.lastname: Xu
authors.forename: Xian-Zheng
authors.initials: XZ
authors.lastname: Zhang
authors.forename: Bo
authors.initials: B
authors.lastname: Wang
authors.forename: Si-Xue
authors.initials: SX
authors.lastname: Cheng
authors.forename: Ren-Xi
authors.initials: RX
authors.lastname: Zhuo
authors.forename: Zong-Chun
authors.initials: ZC
authors.lastname: Wang
mesh_terms: D000178:Acrylamides / Q000737:chemistry; D000180:Acrylic Resins; D000577:Amides / Q000737:chemistry*; D002087:Butyrates / Q000737:chemistry; D020100:Hydrogels / Q000138:chemical synthesis* / Q000737:chemistry; D006885:Hydroxybutyrates / Q000737:chemistry; D011108:Polymers / Q000138:chemical synthesis* / Q000737:chemistry; D013696:Temperature
chemical_list: D000178:Acrylamides; D000180:Acrylic Resins; D000577:Amides; D002087:Butyrates; D020100:Hydrogels; D006885:Hydroxybutyrates; D011108:Polymers; C052970:poly-N-isopropylacrylamide; C479121:3-butenoic acid; C002574:dopastin