[Acute Addisonian crisis in a patient with systemic lupus erythematosus and secondary antiphospholipid syndrome].
This article describes a 57-year-old woman with SLE and positive antiphospholipid and lupus anticoagulant antibodies (Ig type M) who developed an acute Addisonian crisis due to bilateral adrenal haemorrhage. It is important to recognise that bilateral adrenal haemorrhage can be part of the thrombo-embolic complications that are seen in both the primary and the secondary APS. Since there have been a number of similar cases, we suggest that APS with adrenal haemorrhage should be taken into consideration in SLE patients with abdominal pain, fever, nausea, hypotension and hyponatremia.
Jakobsen
Anna Svarre
AS
Nordsjaellands Hospital i Hillerød, Endokrinologisk Klinik E, Medicinsk Funktionsenhed 1. annasvarre@stud.ku.dk
Cvitanich
Veronica Basile
VB
Kirkegaard
Bent Carsten
BC
D000208:Acute Disease; D000224:Addison Disease / Q000175:diagnosis / Q000209:etiology*; D000307:Adrenal Gland Diseases / Q000175:diagnosis / Q000209:etiology*; D016736:Antiphospholipid Syndrome / Q000150:complications*; D005260:Female; D006470:Hemorrhage / Q000175:diagnosis / Q000209:etiology*; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications*; D008875:Middle Aged; D014057:Tomography, X-Ray Computed