title: [Investigating the diagnostic value of MHC-I expression in polymyositis].
abstract: OBJECTIVE
  To investigate the diagnostic value of MHC-I expression in PM.
  
  
  METHODS
  Analyzing the results of clinical and pathological findings and the immunohistochemical findings of MHC-I expression of 54 cases.
  
  
  RESULTS
  Among the 16 patients with PM, 63 percent patients showed inflammatory infiltration, 94 percent showed MHC-I expression; Among 19 patients with progressive muscular dystrophy, 9 percent patients showed inflammatory infiltration, 11 percent showed MHC-I expression. The other 19 patients showed no inflammatory infiltration and MHC-I expression.
  
  
  CONCLUSIONS
  MHC-I expression as a diagnostic index of PM was appropriate, which had ideal sensitivity, specificity and negative likelihood ratio.
authors.affiliation: Department of Neurology, General Hospital of People's Liberation Army, Beijing 100853, China.
authors.forename: Shun-Chang
authors.initials: SC
authors.lastname: Han
authors.forename: Chuan-Qiang
authors.initials: CQ
authors.lastname: Pu
authors.forename: Sen-Yang
authors.initials: SY
authors.lastname: Lang
authors.forename: Wei-Ping
authors.initials: WP
authors.lastname: Wu
authors.forename: Xu-Sheng
authors.initials: XS
authors.lastname: Huang
mesh_terms: D000328:Adult; D005260:Female; D015395:Histocompatibility Antigens Class I / Q000096:biosynthesis*; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D017285:Polymyositis / Q000175:diagnosis* / Q000378:metabolism* / Q000473:pathology; D011237:Predictive Value of Tests
chemical_list: D015395:Histocompatibility Antigens Class I