title: [Blind source separation for fMRI signals using a new independent component analysis algorithm and principal component analysis].
abstract: The application of independent component analysis (ICA) to the functional magnetic resonance imaging (fMRI) data can separate many independent sources. But in the processing there are two difficulties: (1) the data of the fMRI is usually on a large scale, so the computing is time-consuming; (2) we cannot avoid the errors for too heavy computational load, this brings many troubles. Thus we think of reducing the data. In this article we used the standard information theoretic methods to estimate the number of the sources and used the principal component analysis (PCA) to reduce the data. By this process, we estimated the number of the sources and reduced the data successfully; Then we applied the ICA algorithm to the reduced fMRI data; this method raised the speed of operation. After application of the new ICA algorithm and another algorithm (FastICA) to the fMRI data, a comparison was made. The results show that the new algorithm can separate the fMRI data fast and effectively and it is superior to the FastICA on the accuracy of estimating the temporal dynamics of activations.
authors.affiliation: Institute of Computational Biology and Bioinformatics, Dalian University of Technology, Dalian 116023, China.
authors.forename: Weiwei
authors.initials: W
authors.lastname: Zhang
authors.forename: Zhenwei
authors.initials: Z
authors.lastname: Shi
authors.forename: Huanwen
authors.initials: H
authors.lastname: Tang
authors.forename: Yiyuan
authors.initials: Y
authors.lastname: Tang
mesh_terms: D000465:Algorithms; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008279:Magnetic Resonance Imaging / Q000379:methods* / Q000706:statistics & numerical data; D008297:Male; D025341:Principal Component Analysis; D012815:Signal Processing, Computer-Assisted; D012984:Software; D055815:Young Adult