Acral arteriovenous tumor (cirsoid aneurysm): clinical and histopathological analysis of 6 cases.
OBJECTIVE
The aim of this study is to have a further insight into this vascular tumor both clinically and histopathologically.


METHODS
We examined 6 cases of acral arteriovenous tumor. Histochemically Masson trichrom, elastic van Gieson and immunohistochemically Desmin, Factor VIII, S100 and Mast cell tryptase were applied to the paraffin sections to evaluate the content of the vessels and mast cell distribution within the lesion.


RESULTS
Vessels had smooth muscle and laminae elastica in most of the lesions. Arteriovenous anastomosis and glomus cells were not detected in any of the lesions. Mast cell count in the lesion was 215.17+/-42.2 whereas in control cases it was 89.16+/- 28.44. (p<0.001)


CONCLUSIONS
We suggest that acral arteriovenous tumor is an arterial and venous originated neoplasm, not an embryonic remnant or an aneurysm.
Gurbuz
Yesim
Y
Kocaeli University Medical School Department of Pathology Kocaeli, Turkey.
Muezzinoglu
Bahar
B
Apaydin
Rebiay
R
Yumbul
A Zuhal
AZ
D000293:Adolescent; D000328:Adult; D001164:Arteriovenous Fistula / Q000378:metabolism / Q000473:pathology*; D003893:Desmin / Q000378:metabolism; D005169:Factor VIII / Q000378:metabolism; D005260:Female; D006391:Hemangioma / Q000378:metabolism / Q000473:pathology*; D006801:Humans; D008297:Male; D008407:Mast Cells; D008875:Middle Aged; D009383:Neoplasms, Vascular Tissue / Q000378:metabolism / Q000473:pathology*; D009418:S100 Proteins / Q000378:metabolism; D053802:Tryptases / Q000378:metabolism
D003893:Desmin; D009418:S100 Proteins; D005169:Factor VIII; D053802:Tryptases