title: Coxiella burnetii and acute exacerbations/infections in patients with chronic lung disease.
abstract: The aim of the present study was to determine the incidence of Q fever in patients with an acute exacerbation of a chronic lower respiratory tract infection. Eighty patients treated for acute exacerbation of chronic lower respiratory tract infections during a 30-month period were studied. Q fever was diagnosed by ELISA. Two elderly woman with pre-existing bronchiectasis (2.5%) were diagnosed as having an acute infection by Coxiella burnetii. The acute illness was considered to be a result of mixed infection with Pseudomonas aeruginosa and Haemophilus influenzae with C. burnetii. Co-infection with C. burnetii can occur during a bacterial exacerbation of a chronic lower respiratory tract infection.
authors.affiliation: Center of Respiratory Diseases, Kawasaki Medical School Kawasaki Hospital, Okayama, Japan. n.okimoto@kawasaki-hp.jp
authors.forename: Niro
authors.initials: N
authors.lastname: Okimoto
authors.forename: Takashi
authors.initials: T
authors.lastname: Kibayashi
authors.forename: Kimihiro
authors.initials: K
authors.lastname: Mimura
authors.forename: Kenji
authors.initials: K
authors.lastname: Yamato
authors.forename: Takeyuki
authors.initials: T
authors.lastname: Kurihara
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Honda
authors.forename: Kohichi
authors.initials: K
authors.lastname: Osaki
authors.forename: Naoko
authors.initials: N
authors.lastname: Asaoka
authors.forename: Hideo
authors.initials: H
authors.lastname: Ohba
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001987:Bronchiectasis / Q000453:epidemiology*; D002908:Chronic Disease; D015897:Comorbidity; D005260:Female; D006192:Haemophilus Infections / Q000453:epidemiology; D006193:Haemophilus influenzae; D006801:Humans; D015994:Incidence; D011552:Pseudomonas Infections / Q000453:epidemiology; D029424:Pulmonary Disease, Chronic Obstructive / Q000453:epidemiology; D011658:Pulmonary Fibrosis / Q000453:epidemiology; D011778:Q Fever / Q000453:epidemiology*; D014397:Tuberculosis, Pulmonary / Q000453:epidemiology