Serotypes, antimicrobial susceptibility, and gyr A gene mutation of Campylobacter jejuni isolates from humans and chickens in Thailand.
In Thailand, 51% (36/70) Campylobacter jejuni isolates from humans and 68% (47/69) isolates from poultry were classified into 10 Penner serotypes (serotype B, C, R, E, G, A, K, D, I, and L) and 9 serotypes (serotype A, C, I, K, B, E, S, D, and L), respectively. The rate of antimicrobial drug resistance to nalidixic acid, ciprofloxacin, ampicillin, tetracycline, and erythromycin shown by human isolates were 96%, 96%, 29%, 57%, and 14%, while that shown by poultry isolates were 77%, 77%, 22%, 26%, and 17%, respectively. All quinolone-resistant strains contained a mutation in the gyrA gene (T(86)-->I(86)), suggesting that the strains were already widespread in Thailand.
Boonmar
Sumalee
S
Faculty of Veterinary Medicine, Kasetsart University, Bangkok 10900, Thailand.
Morita
Yukio
Y
Fujita
Masahiro
M
Sangsuk
Leelaowadee
L
Suthivarakom
Karun
K
Padungtod
Pawin
P
Maruyama
Soichi
S
Kabeya
Hidenori
H
Kato
Masahiko
M
Kozawa
Kunihisa
K
Yamamoto
Shigeki
S
Kimura
Hirokazu
H
D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D002169:Campylobacter Infections / Q000382:microbiology*; D016123:Campylobacter jejuni / Q000187:drug effects* / Q000201:enzymology / Q000235:genetics* / Q000302:isolation & purification; D002645:Chickens / Q000382:microbiology*; D027081:DNA Gyrase / Q000235:genetics*; D004271:DNA, Fungal / Q000235:genetics; D024881:Drug Resistance, Bacterial; D006801:Humans; D008826:Microbial Sensitivity Tests; D017354:Point Mutation; D016133:Polymerase Chain Reaction; D011201:Poultry Diseases / Q000382:microbiology*; D012703:Serotyping; D013785:Thailand
D000900:Anti-Bacterial Agents; D004271:DNA, Fungal; D027081:DNA Gyrase