[Floppy-iris syndrome associated with tamsulosin. A prospective case-control study].
OBJECTIVE
The main objectives of this study were: To assess the incidence of the intraoperative floppy-iris syndrome associated with tamsulosin and to analyse the incidence of intraoperative and postoperative complications as compared to a control group. Secondary objectives were: to describe the pupillary modifications associated with tamsulosin and to quantify the endothelial cell loss.


METHODS
A prospective review of 38 eyes of 38 patients was performed. Patients were assigned to two different groups. Group 1 (cases) included 19 eyes of 19 male patients taking tamsulosin, and group 2 (controls) included 19 eyes of 19 male patients not taking tamsulosin.


RESULTS
Only two patients (10%) of our study had the complete triad seen in floppy-iris syndrome; 9 patients (47%) showed 2 of the 3 main features of the syndrome and only 2 patients showed iris billowing during phacoemulsification. None of the patients in group 2 showed any of the characteristic intraoperative features. The complication rate was similar in both groups.


CONCLUSIONS
Intraoperative floppy-iris syndrome occurred in 67% of the patients treated with tamsulosin. The only postoperative secondary effect was a lower pupil reactivity in patients taking tamsulosin.
Bidaguren
A
A
Hospital Donostia, San Sebastián, Guipúzcoa, España. aritzbidaguren@kaixo.com
Irigoyen
C
C
Mendicute
J
J
Gutiérrez
E
E
Gibelalde
A
A
Ubeda
M
M
D000317:Adrenergic alpha-Antagonists / Q000009:adverse effects*; D000368:Aged; D016022:Case-Control Studies; D002387:Cataract Extraction; D006801:Humans; D015994:Incidence; D007431:Intraoperative Complications / Q000139:chemically induced* / Q000453:epidemiology; D007499:Iris Diseases / Q000139:chemically induced* / Q000453:epidemiology; D008297:Male; D011446:Prospective Studies; D013449:Sulfonamides / Q000009:adverse effects*; D013577:Syndrome; D000077409:Tamsulosin
D000317:Adrenergic alpha-Antagonists; D013449:Sulfonamides; D000077409:Tamsulosin