Rapid progression of mild to moderate aortic stenosis in patients older than 80 years.
OBJECTIVE
The purpose of this study was to evaluate the rate of progression of mild and moderate aortic stenosis in patients aged 80 years and older.


METHODS
In all, 41 patients with mild and moderate aortic stenosis were included and divided into two groups by age: 19 patients aged 80 years and older (mean 84 +/- 4 years), and 21 patients younger than 80 years (mean 66 +/- 6 years).


RESULTS
The rate of degression of aortic valve area was more rapid in the 80 years and older age group than that in the younger than 80 years age group (-0.05 +/- 0.06 and -0.10 +/- 0.08 cm2/y, P = .014). Univariate and multivariate analysis of the rate of degression of aortic valve area were performed, and age was the only independent predictor of the rate of degression of aortic valve area.


CONCLUSIONS
Progression of mild and moderate aortic stenosis in patients aged 80 years and older was more rapid than that in those aged younger than 80 years.
Kume
Teruyoshi
T
Department of Cardiology, Kawasaki Medical School, Kurashiki, Japan. tteru@med.kawasaki-m.ac.jp <tteru@med.kawasaki-m.ac.jp>
Kawamoto
Takahiro
T
Okura
Hiroyuki
H
Watanabe
Nozomi
N
Toyota
Eiji
E
Neishi
Yoji
Y
Okahashi
Noriko
N
Yamada
Ryotaro
R
Yoshida
Kiyoshi
K
D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D000375:Aging; D001024:Aortic Valve Stenosis / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D018450:Disease Progression; D005260:Female; D006801:Humans; D008297:Male; D014463:Ultrasonography