title: Active renal secretion of NXY-059, a novel neuroprotectant, is mediated via an organic acid transporter.
authors.affiliation: AstraZeneca R&D, SE-151 85 Södertälje, Sweden.
authors.forename: Yi-Fang
authors.initials: YF
authors.lastname: Cheng
authors.forename: Stig
authors.initials: S
authors.lastname: Strid
authors.forename: Olof
authors.initials: O
authors.lastname: Borgå
authors.forename: Dag
authors.initials: D
authors.lastname: Nilsson
authors.forename: Johan
authors.initials: J
authors.lastname: Wemer
mesh_terms: D000328:Adult; D001557:Benzenesulfonates / Q000009:adverse effects / Q000097:blood / Q000493:pharmacokinetics* / Q000652:urine; D002927:Cimetidine / Q000494:pharmacology; D004347:Drug Interactions; D005260:Female; D005919:Glomerular Filtration Rate; D006801:Humans; D007444:Inulin; D007677:Kidney Function Tests; D008297:Male; D008875:Middle Aged; D018696:Neuroprotective Agents / Q000009:adverse effects / Q000097:blood / Q000493:pharmacokinetics* / Q000652:urine; D027361:Organic Anion Transporters / Q000037:antagonists & inhibitors / Q000502:physiology*; D011339:Probenecid / Q000494:pharmacology
chemical_list: D001557:Benzenesulfonates; D018696:Neuroprotective Agents; D027361:Organic Anion Transporters; C120851:disufenton sodium; D002927:Cimetidine; D007444:Inulin; D011339:Probenecid