Formation of five-membered carbocycles by intramolecular palladium-catalyzed ring opening of tert-cyclobutanols.
We report herein stereoselective formation of a functionalized five-membered carbocycle bearing a quaternary center by intramolecular palladium-catalyzed ring-opening of o-bromophenyl-tethered tert-cyclobutanols.
Ethirajan
Manivannan
M
Department of Chemistry, Wayne State University, 5101 Cass Avenue, Detroit, MI 48202, USA.
Oh
Heong-Sub
HS
Cha
Jin Kun
JK
D002384:Catalysis; D018360:Crystallography, X-Ray; D003500:Cyclization; D003503:Cyclobutanes / Q000138:chemical synthesis*; D009682:Magnetic Resonance Spectroscopy; D010165:Palladium / Q000737:chemistry*; D013237:Stereoisomerism
D003503:Cyclobutanes; D010165:Palladium