title: [ALK-negative primary gastric anaplastic large cell lymphoma].
abstract: A 56-year-old Japanese woman was admitted to our hospital with upper abdominal pain. Gastroendoscopy revealed a Borrmann III type tumor which was diagnosed from the biopsied specimen as an anaplastic large cell lymphoma (ALCL). CT scan revealed para-aortic and left-supra clavicular lymph node swelling, so her clinical stage was defined as IIIE according to the Ann Arbor classification. The patient first of all received CHOP therapy, however her lymphoma lesions increased in size. Therefore she underwent salvage chemotherapy regimens and autologous peripheral blood stem cell transplantation (APBSCT). She has remained in complete clinical remission (CCR) for eleven months after the APBSCT.
authors.affiliation: Division of Clinical Rheumatology and Haematology, Department of Medicine, Sapporo City General Hospital.
authors.forename: Kazuki
authors.initials: K
authors.lastname: Koizumi
authors.forename: Kouichiro
authors.initials: K
authors.lastname: Minauchi
authors.forename: Toshio
authors.initials: T
authors.lastname: Odani
authors.forename: Makoto
authors.initials: M
authors.lastname: Kondo
authors.forename: Akio
authors.initials: A
authors.lastname: Takada
authors.forename: Masaya
authors.initials: M
authors.lastname: Mukai
mesh_terms: D000077548:Anaplastic Lymphoma Kinase; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage / Q000627:therapeutic use; D014408:Biomarkers, Tumor / Q000032:analysis*; D002945:Cisplatin / Q000008:administration & dosage; D003131:Combined Modality Therapy; D015251:Epirubicin / Q000008:administration & dosage; D005047:Etoposide / Q000008:administration & dosage; D005260:Female; D006801:Humans; D007069:Ifosfamide / Q000008:administration & dosage; D016403:Lymphoma, Large B-Cell, Diffuse / Q000175:diagnosis / Q000473:pathology / Q000628:therapy*; D008875:Middle Aged; D036102:Peripheral Blood Stem Cell Transplantation; D011505:Protein-Tyrosine Kinases / Q000032:analysis*; D020794:Receptor Protein-Tyrosine Kinases; D012074:Remission Induction; D016879:Salvage Therapy; D013274:Stomach Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000628:therapy*; D014182:Transplantation, Autologous
chemical_list: D014408:Biomarkers, Tumor; D015251:Epirubicin; D005047:Etoposide; C000626173:ALK protein, human; D000077548:Anaplastic Lymphoma Kinase; D011505:Protein-Tyrosine Kinases; D020794:Receptor Protein-Tyrosine Kinases; D002945:Cisplatin; D007069:Ifosfamide