Insulin analogues in the treatment of diabetes in pregnancy.
This review reports the literature on the safety and efficacy of insulin analogues in pregnancy and thereby enables the clinician to choose the optimal insulin treatment protocol to achieve and maintain normoglycemia throughout pregnancies complicated by diabetes. This article also reviews the literature on the insulin analog during pregnancy and presents the authors' opinion as to the safety and efficacy of insulin analog treatment for the pregnant diabetic woman.
Singh
Charanpal
C
Sansum Diabetes Research Institute, 2219 Bath Street, Santa Barbara, CA 93105, USA.
Jovanovic
Lois
L
D016640:Diabetes, Gestational / Q000188:drug therapy*; D005260:Female; D006801:Humans; D007004:Hypoglycemic Agents / Q000627:therapeutic use*; D007328:Insulin / Q000031:analogs & derivatives / Q000378:metabolism / Q000627:therapeutic use; D061267:Insulin Aspart; D000069057:Insulin Detemir; D000069036:Insulin Glargine; D061268:Insulin Lispro; D049528:Insulin, Long-Acting; D011247:Pregnancy / Q000378:metabolism; D011254:Pregnancy in Diabetics / Q000188:drug therapy*; D017526:Receptor, IGF Type 1 / Q000502:physiology
D007004:Hypoglycemic Agents; D007328:Insulin; D061268:Insulin Lispro; D049528:Insulin, Long-Acting; D000069036:Insulin Glargine; D000069057:Insulin Detemir; C479079:insulin glulisine; D061267:Insulin Aspart; D017526:Receptor, IGF Type 1