Increased splenic fluorodeoxyglucose uptake in a patient with granulomatous angitis.
Although utility of 18F-fluoro-2-deoxy-D-glucose positron emission tomography (FDG-PET) has been rehearsed in large vessel vasculitides, it is not known if small vessel vasculitides are also associated with increased FDG uptake. Hereby described is a 64-year-old female patient with prolonged fever and splenomegaly, which was depicted as a hot area in FDG-PET. Splenectomy disclosed microaneurysms, giant cell granuloma, perivascular leukocytic infiltration with fibrinoid necrosis, consistent with granulomatous angitis. Serum myeloperoxidase-antineutrophil cytoplasmic antibody was positive. The present case illustrates that vasculitides affecting small vessels present increased FDG uptake as do those affecting large vessels.
Maruoka
Hiroshi
H
Department of Internal Medicine, Kurume University School of Medicine. maruoka@med.kurume-u.ac.jp
Koga
Takeharu
T
Takeo
Masaaki
M
Honda
Seiyo
S
Yuge
Kentaro
K
Fukuda
Takaaki
T
Aizawa
Hisamichi
H
D005260:Female; D019788:Fluorodeoxyglucose F18 / Q000493:pharmacokinetics*; D006801:Humans; D008875:Middle Aged; D049268:Positron-Emission Tomography / Q000295:instrumentation; D011859:Radiography; D019275:Radiopharmaceuticals / Q000493:pharmacokinetics*; D013154:Spleen / Q000378:metabolism*; D013163:Splenomegaly / Q000000981:diagnostic imaging / Q000209:etiology / Q000473:pathology; D016896:Treatment Outcome; D020293:Vasculitis, Central Nervous System / Q000150:complications / Q000378:metabolism* / Q000473:pathology / Q000628:therapy
D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18