Tandem Knoevenagel-Michael addition of aryl sulfonimines with diethyl malonate for synthesis of arylidene dimalonates.
A highly efficient, one-flask tandem Knoevenagel-Michael addition reaction of sulfonimines with diethyl malonate in the presence of a catalytic amount of base affords the corresponding arylidene dimalonates in good to excellent yields.
Fan
Renhua
R
Department of Chemistry, Fudan University, 220 Handan Road, Shanghai 200433, China. rhfan@fudan.edu.cn
Wang
Weizi
W
Pu
Dongming
D
Wu
Jie
J
D007097:Imines / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D008314:Malonates / Q000138:chemical synthesis* / Q000737:chemistry*
D007097:Imines; D008314:Malonates; C498810:diethyl malonate; C030290:malonic acid