title: [Central nervous system abnormalities namely secondary brain tumors].
abstract: A 22 year-old-man with acute lymphoblastic leukaemia had received prophylactic cranial irradiation and intrathecal chemotherapy. Eighteen years later a cerebellar glioblastoma multiforme was diagnosed. The authors speculate about the possibility that this tumor may have been radiation and/or chemotherapy induced. Improvement in neuroimaging techniques, in particular magnetic resonance imaging, has helped characterize Central Nervous System abnormalities, namely secondary brain tumours.
authors.affiliation: Serviço de Neurorradiologia, Hospital Garcia de Orta, Almada.
authors.forename: A
authors.initials: A
authors.lastname: Vieira Santos
authors.forename: Pedro
authors.initials: P
authors.lastname: Vilela
authors.forename: Luís
authors.initials: L
authors.lastname: Mateus
authors.forename: Paulo F
authors.initials: PF
authors.lastname: Saraiva
authors.forename: Augusto
authors.initials: A
authors.lastname: Goulão
mesh_terms: D000328:Adult; D001932:Brain Neoplasms / Q000175:diagnosis* / Q000209:etiology; D017809:Fatal Outcome; D005909:Glioblastoma / Q000175:diagnosis* / Q000209:etiology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D016609:Neoplasms, Second Primary / Q000175:diagnosis* / Q000209:etiology; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000532:radiotherapy*; D014057:Tomography, X-Ray Computed