Membrane curvature: the power of bananas, zeppelins and boomerangs.
New work on the ability of IRSp53/MIM domains to induce negative membrane curvature sheds light on the mechanisms used to generate actin-rich cell protrusions.
Cory
Giles O C
GO
Henry Wellcome Integrated Signalling Laboratories, Department of Biochemistry, School of Medical Sciences, University of Bristol, Bristol BS8 1TD, UK. giles.cory@bristol.ac.uk
Cullen
Peter J
PJ
D000199:Actins / Q000378:metabolism*; D000818:Animals; D002462:Cell Membrane / Q000378:metabolism / Q000648:ultrastructure*; D019281:Dimerization; D004705:Endocytosis / Q000502:physiology*; D006801:Humans; D008958:Models, Molecular; D009419:Nerve Tissue Proteins / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D011554:Pseudopodia / Q000378:metabolism* / Q000648:ultrastructure
D000199:Actins; C119539:BAIAP2 protein, human; D009419:Nerve Tissue Proteins