Isotope effects as probe of constrictive and intrinsic binding in hemicarceplexes.
Kinetic isotope effects (KIE) of hemicarceplex dissociation for naphthalene and p-xylene hemicarceplexes with partially and fully deuterated guests have been measured. The KIEs are consistent with the absence of steric effects in the transition states of hemicarceplex dissociation, which supports an earlier interpretation of constrictive binding energy in hemicarceplexes as being primarily controlled by different forms of gating.
Liu
Yong
Y
Department of Chemistry and Chemical Biology, Rutgers-The State University of New Jersey, Piscataway, New Jersey 08854, USA.
Warmuth
Ralf
R