title: Malignant melanoma of the sinonasal mucosa: two case reports and a review.
abstract: Malignant melanoma of the sinonasal cavity is an uncommon disease, and therefore a limited amount of data exists regarding its optimal treatment. The course of the disease is highly variable. Individual survival is also highly variable, but the overall prognosis is poor; probably because patients generally present at a late stage and because the disease has a proclivity for distant dissemination. We describe 2 recent cases of primary malignant melanoma of the sinonasal mucosa, and we review the literature.
authors.affiliation: Department of Otolaryngology, Naval Medical Center, San Diego, CA 92134-1005, USA. arsanderson@nmcsd.med.navy.mil
authors.forename: Alicia R
authors.initials: AR
authors.lastname: Sanderson
authors.forename: Brendan
authors.initials: B
authors.lastname: Gaylis
mesh_terms: D000368:Aged; D000951:Antigens, Neoplasm; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D008297:Male; D008543:Melanins / Q000378:metabolism; D008545:Melanoma / Q000175:diagnosis* / Q000378:metabolism / Q000601:surgery; D058950:Melanoma-Specific Antigens; D009363:Neoplasm Proteins / Q000378:metabolism; D009364:Neoplasm Recurrence, Local / Q000601:surgery; D009669:Nose Neoplasms / Q000175:diagnosis* / Q000378:metabolism / Q000601:surgery; D010255:Paranasal Sinus Neoplasms / Q000175:diagnosis* / Q000378:metabolism / Q000601:surgery; D011859:Radiography; D020545:Respiratory Mucosa / Q000000981:diagnostic imaging / Q000378:metabolism / Q000473:pathology / Q000601:surgery; D009418:S100 Proteins / Q000378:metabolism
chemical_list: D000951:Antigens, Neoplasm; D008543:Melanins; D058950:Melanoma-Specific Antigens; D009363:Neoplasm Proteins; D009418:S100 Proteins