title: Severe hypernatremia and hyperosmolality exacerbated by an herbal preparation in a patient with diabetic ketoacidosis.
abstract: This article reports a case of severe reversible hypernatremia exacerbated by an herbal agent "goldenseal" (Hydrastis canadensis) in an 11-year-old girl with new onset type I diabetes mellitus presented with diabetic ketoacidosis. A literature review is presented and possible mechanism of hypernatremia caused by this herbal preparation is discussed.
authors.affiliation: Division of Pediatric Endocrinology, University of South Alabama Medical Center, Mobile, Alabama 36617-2297, USA. sbhowmick@usouthal.edu
authors.forename: Samar K
authors.initials: SK
authors.lastname: Bhowmick
authors.forename: Olivette T
authors.initials: OT
authors.lastname: Hundley
authors.forename: Kenneth R
authors.initials: KR
authors.lastname: Rettig
mesh_terms: D002648:Child; D016883:Diabetic Ketoacidosis / Q000150:complications / Q000209:etiology / Q000503:physiopathology*; D005260:Female; D006801:Humans; D039321:Hydrastis / Q000009:adverse effects; D006955:Hypernatremia / Q000150:complications / Q000503:physiopathology*