title: Immunohistochemical study on the distribution of canonical transient receptor potential channels in rat basal ganglia.
abstract: In the present study, we examined the localizations of canonical transient receptor potential channels (TRPCs) in rat basal ganglia. The dot-like staining pattern of TRPC5 was observed through the globus pallidus (GP) and caudate-putamen. TRPC7 had a strikingly high level of expression in the neuropil in the GP. In the subthalamic nucleus, strong staining for TRPC5 was observed in the cell bodies, while moderate to high immunoreactivies for TRPC1, TRPC3, TRPC4 and TRPC7 were found in the cell bodies and surrounding neuropil. In the substantia nigra, immunoreactivities for TRPC3 and TRPC7 were prominent in the cell bodies and several processes in the pars compacta and pars reticulata. TRPC6 was expressed in the neuropil, not in the cell bodies. This study may provide useful data for the future investigations on the structural and functional properties of TRPCs.
authors.affiliation: Department of Anatomy, College of Medicine, Chung-Ang University, 221 Heukseok-Dong, Dongjak-Gu, Seoul 156-756, South Korea.
authors.forename: Yoon Hee
authors.initials: YH
authors.lastname: Chung
authors.forename: Daejin
authors.initials: D
authors.lastname: Kim
authors.forename: Nam Joo
authors.initials: NJ
authors.lastname: Moon
authors.forename: Chang Seok
authors.initials: CS
authors.lastname: Oh
authors.forename: Eunju
authors.initials: E
authors.lastname: Lee
authors.forename: Dong Hoon
authors.initials: DH
authors.lastname: Shin
authors.forename: Sung Su
authors.initials: SS
authors.lastname: Kim
authors.forename: Won Bok
authors.initials: WB
authors.lastname: Lee
authors.forename: Jun-Young
authors.initials: JY
authors.lastname: Lee
authors.forename: Choong Ik
authors.initials: CI
authors.lastname: Cha
mesh_terms: D000818:Animals; D001479:Basal Ganglia / Q000166:cytology / Q000378:metabolism*; D005455:Fluorescent Antibody Technique; D007150:Immunohistochemistry; D009474:Neurons / Q000378:metabolism; D019581:Neuropil / Q000378:metabolism; D051381:Rats; D017207:Rats, Sprague-Dawley; D050051:Transient Receptor Potential Channels / Q000502:physiology*
chemical_list: D050051:Transient Receptor Potential Channels