Sequential bilateral solitary extramedullary plasmacytoma of the ciliary body.
OBJECTIVE
To report bilateral plasmacytoma of the ciliary body in a healthy patient.


METHODS
Clinicopathologic report.


RESULTS
A 55-year-old woman with iritis developed an iridociliary mass in the left eye. Systemic evaluation was normal. Fine-needle aspiration (FNAB) of the mass revealed atypical, binucleate plasmacytoid cells with positive leukocyte common antigen staining, suggestive of plasmacytoma. The tumor was treated with 4000 cGy by using custom-designed plaque radiotherapy. The tumor completely resolved. Two years later, a similar iridociliary mass was noted in the right eye, and FNAB confirmed plasmacytoma. Plaque radiotherapy of 4000 cGy was delivered. At the 3-year follow-up, there has been no local recurrence or evidence of systemic multiple myeloma or monoclonal gammopathy.


CONCLUSIONS
Extramedullary plasmacytoma can involve the uvea and rarely manifest multiplicity. Long-term monitoring for systemic plasma cell dyscrasia is warranted.
Shields
Carol L
CL
Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, PA 19107, USA. carol.shields@shieldsoncology.com
Chong
William H
WH
Ehya
Hormoz
H
Shields
Jerry A
JA
D014408:Biomarkers, Tumor / Q000032:analysis; D044963:Biopsy, Fine-Needle; D001918:Brachytherapy; D002924:Ciliary Body / Q000000981:diagnostic imaging / Q000473:pathology* / Q000528:radiation effects; D005260:Female; D006801:Humans; D033401:Microscopy, Acoustic; D008875:Middle Aged; D010954:Plasmacytoma / Q000737:chemistry / Q000000981:diagnostic imaging / Q000473:pathology* / Q000532:radiotherapy; D014604:Uveal Neoplasms / Q000737:chemistry / Q000000981:diagnostic imaging / Q000473:pathology* / Q000532:radiotherapy
D014408:Biomarkers, Tumor