Stem cell self-renewal: centrosomes on the move.
Three recent studies show that centrosome asymmetry correlates with self-renewal of Drosophila neural and germline stem cells and that equalizing centrosomes disrupts asymmetric cell division.
Cabernard
Clemens
C
Institute of Neuroscience, HHMI, University of Oregon, Eugene, Oregon 97403, USA.
Doe
Chris Q
CQ
D000818:Animals; D002454:Cell Differentiation; D002455:Cell Division; D018385:Centrosome / Q000502:physiology*; D004330:Drosophila / Q000166:cytology* / Q000254:growth & development / Q000502:physiology; D005854:Germ Cells / Q000166:cytology / Q000648:ultrastructure; D007814:Larva / Q000166:cytology / Q000502:physiology; D008297:Male; D009474:Neurons / Q000166:cytology / Q000648:ultrastructure; D013234:Stem Cells / Q000166:cytology* / Q000648:ultrastructure*