[Solitary intracerebral langerhans cell histiocytosis: report of one case and literature review].
BACKGROUND
Langerhans cell histiocytosis is a multivisceral pathology. Neurological manifestations are rare.


METHODS
We report the case of a 31 year old man hospitalized for left partial motor seizure revealing a right frontal tumor with criteria for histiocytosis X. The histological and biological examination found criteria for Langerhans cell histiocytosis (CD1a and S100 reactivity). The check-up for extracerebral localisations of the disease was negative. The outcome was favourable after a total surgical resection. The review of the literature and a discussion on neurological manifestations of this disease were carried out.


CONCLUSIONS
A neurological manifestation can be the first and only symptom of a Langerhans cell histiocytosis.
Mathis
S
S
Clinique neurologique, université de Poitiers, CHU de Poitiers, 2, rue de la Milétrie, 86021 Poitiers cedex 05, France. s.mathis@chu-poitiers.fr
Levillain
P
P
Vandermarcq
P
P
Gil
R
R
Auche
V
V
Ciron
J
J
Neau
J-P
JP
D000328:Adult; D018949:Antigens, CD1 / Q000032:analysis; D001927:Brain Diseases / Q000473:pathology*; D006646:Histiocytosis, Langerhans-Cell / Q000473:pathology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D012640:Seizures / Q000209:etiology*
D018949:Antigens, CD1; C419393:CD1a antigen