title: Tc-99m ciprofloxacin imaging in acute cholecystitis.
abstract: OBJECTIVE
  To evaluate the efficacy of a new nuclear imaging Infecton (Tc-99m ciprofloxacin) for the diagnosis of acute cholecystitis.
  
  
  METHODS
  Sixteen patients thought to have acute cholecystitis were included in this study. The diagnosis of acute cholecystitis was made based on clinical symptoms and ultrasonographic and pathologic findings.
  
  
  RESULTS
  The 16 patients were composed of 12 acute and 4 chronic cholecystitis patients. Twelve patients with acute cholecystitis were image-positive, including one false-positive. Four patients with chronic cholecystitis were image-negative, of whom three were true-negative. This nuclear imaging had a sensitivity of 91.7%, a specificity of 75%, a positive-predictive value of 91.7%, and a negative-predictive value of 75%.
  
  
  CONCLUSIONS
  Tc-99m ciprofloxacin imaging is easy to perform and applicable for the diagnosis of acute cholecystitis.
authors.affiliation: Department of Surgery, Inha University Hospital, 7-206, 3 Ga Shinheung-dong, Jung-Gu, Incheon 400-711, South Korea.
authors.forename: Yun-Mee
authors.initials: YM
authors.lastname: Choe
authors.forename: Wonsick
authors.initials: W
authors.lastname: Choe
authors.forename: Keon-Young
authors.initials: KY
authors.lastname: Lee
authors.forename: Seung-Ik
authors.initials: SI
authors.lastname: Ahn
authors.forename: Kwang
authors.initials: K
authors.lastname: Kim
authors.forename: Young Up
authors.initials: YU
authors.lastname: Cho
authors.forename: Sun Keun
authors.initials: SK
authors.lastname: Choi
authors.forename: Yoon-Seok
authors.initials: YS
authors.lastname: Hur
authors.forename: Sei-Joong
authors.initials: SJ
authors.lastname: Kim
authors.forename: Kee-Chun
authors.initials: KC
authors.lastname: Hong
authors.forename: Seok-Hwan
authors.initials: SH
authors.lastname: Shin
authors.forename: Kyung-Rae
authors.initials: KR
authors.lastname: Kim
authors.forename: Ze-Hong
authors.initials: ZH
authors.lastname: Woo
mesh_terms: D000208:Acute Disease; D000328:Adult; D000368:Aged; D002764:Cholecystitis / Q000000981:diagnostic imaging*; D002939:Ciprofloxacin / Q000031:analogs & derivatives*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015609:Organotechnetium Compounds; D011877:Radionuclide Imaging; D012680:Sensitivity and Specificity
chemical_list: D015609:Organotechnetium Compounds; C431804:Technetium Tc 99m ciprofloxacin; D002939:Ciprofloxacin