Hepatoprotective activity of the Leucas lavandulaefolia on D(+)galactosamine-induced hepatic injury in rats.
The chloroform extract of Leucas lavandulaefolia at an oral dose of 200 mg/kg and 400 mg/kg exhibited a significant protection on D(+)galactosamine induced liver damage in rats. Silymarin (25 mg/kg), a known hepatoprotective drug used as a standard also exhibited a significant activity.
Chandrashekar
K S
KS
Department of Pharmacognosy, NGSM Institute of Pharmaceutical Sciences, Nanthoor, Mangalore, India. cksbhat@yahoo.co.in
Prasanna
K S
KS
Joshi
A B
AB
D000284:Administration, Oral; D000818:Animals; D056486:Chemical and Drug Induced Liver Injury / Q000209:etiology / Q000517:prevention & control*; D005688:Galactosamine; D019686:Lamiaceae; D008297:Male; D008517:Phytotherapy; D010936:Plant Extracts / Q000008:administration & dosage / Q000627:therapeutic use*; D020011:Protective Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D051381:Rats; D017208:Rats, Wistar
D010936:Plant Extracts; D020011:Protective Agents; D005688:Galactosamine