[Hla-B27 gene: polymorphism, evolution, distribution, and association with spondyloartopathies].
The association between HLA-B27 and ankylosing spondylitis is well established more than thirty years. In spite of numerous studies in this field, a lot of unknown is still present. In this review, polymorphism, evolution, distribution and current pathogenetic hypotheses are presented.
Grubić
Zorana
Z
Klinika za urologiju, Klinicki bolnicki centar Zagreb, Kispatićeva 12, 10000 Zagreb. zgrubic@kbc-zagreb.hr
D000818:Animals; D005787:Gene Frequency; D015796:HLA-B27 Antigen / Q000235:genetics* / Q000276:immunology; D006801:Humans; D011110:Polymorphism, Genetic; D025242:Spondylarthropathies / Q000235:genetics* / Q000276:immunology
D015796:HLA-B27 Antigen