title: Ultrasound-guided percutaneous cholecystostomy for acute neonatal biliary obstruction.
abstract: Use of a percutaneously-inserted cholecystostomy drainage tube is an effective therapeutic option for acute hyperbilirubinemia in severely-ill adult patients, but to our knowledge has not been previously reported in infants. We describe an infant who developed acute extrahepatic biliary tract obstruction with marked conjugated (direct) hyperbilirubinemia, and who was determined to be an unsuitable surgical candidate. Ultrasound-guided percutaneous cholecystostomy was performed and resulted in prompt, significant, and sustained decline in serum bilirubin levels. Potential risks and benefits, as well as suggested indications for the procedure are discussed.
authors.affiliation: Department of Pediatrics, University of Illinois Medical Center, Chicago, IL 60612, USA. rhelin1@uic.edu
authors.forename: Radley
authors.initials: R
authors.lastname: Helin
authors.forename: Rama
authors.initials: R
authors.lastname: Bhat
authors.forename: Bhaskara
authors.initials: B
authors.lastname: Rao
mesh_terms: D001663:Bilirubin / Q000097:blood; D002763:Cholecystectomy / Q000379:methods*; D001651:Cholestasis, Extrahepatic / Q000601:surgery*; D006554:Hernia, Umbilical; D006801:Humans; D007231:Infant, Newborn; D041781:Jaundice, Obstructive / Q000601:surgery*; D016343:Monitoring, Intraoperative; D016896:Treatment Outcome
chemical_list: D001663:Bilirubin