title: Percutaneous transhepatic portography for the treatment of early portal vein thrombosis after surgery.
abstract: We treated three cases of early portal vein thrombosis (PVT) by minimally invasive percutaneous transhepatic portography. All patients developed PVT within 30 days of major hepatic surgery (one case each of orthotopic liver transplantation, splenectomy in a previous liver transplant recipient, and right extended hepatectomy with resection and reconstruction of the left branch of the portal vein for tumor infiltration). In all cases minimally invasive percutaneous transhepatic portography was adopted to treat this complication by mechanical fragmentation and pharmacological lysis of the thrombus. A vascular stent was also positioned in the two cases in which the thrombosis was related to a surgical technical problem. Mechanical fragmentation of the thrombus with contemporaneous local urokinase administration resulted in complete removal of the clot and allowed restoration of normal blood flow to the liver after a median follow-up of 37 months. PVT is an uncommon but severe complication after major surgery or liver transplantation. Surgical thrombectomy, with or without reconstruction of the portal vein, and retransplantation are characterized by important surgical morbidity and mortality. Based on our experience, minimally invasive percutaneous transhepatic portography should be considered an option toward successful recanalization of early PVT after major liver surgery including transplantation. Balloon dilatation and placement of a vascular stent could help to decrease the risk of recurrent thrombosis when a defective surgical technique is the reason for the thrombosis.
authors.affiliation: Department of Surgery & Transplantation, University Hospital of Udine, Via Colugna 50, 33100 Udine, Italy. adanigl@hotmail.com
authors.forename: Gian Luigi
authors.initials: GL
authors.lastname: Adani
authors.forename: Umberto
authors.initials: U
authors.lastname: Baccarani
authors.forename: Andrea
authors.initials: A
authors.lastname: Risaliti
authors.forename: Massimo
authors.initials: M
authors.lastname: Sponza
authors.forename: Daniele
authors.initials: D
authors.lastname: Gasparini
authors.forename: Fabrizio
authors.initials: F
authors.lastname: Bresadola
authors.forename: Dino
authors.initials: D
authors.lastname: de Anna
authors.forename: Vittorio
authors.initials: V
authors.lastname: Bresadola
mesh_terms: D000800:Angioplasty, Balloon / Q000379:methods*; D005260:Female; D006498:Hepatectomy; D006801:Humans; D016031:Liver Transplantation; D008297:Male; D008875:Middle Aged; D011169:Portal Vein; D011172:Portography / Q000379:methods*; D011183:Postoperative Complications / Q000175:diagnosis / Q000628:therapy*; D015607:Stents; D015912:Thrombolytic Therapy; D013927:Thrombosis / Q000175:diagnosis / Q000628:therapy*