Antiphospholipid syndrome: a predisposing factor for early onset HELLP syndrome.
Hemolysis elevated liver enzymes low platelets syndrome (HELLP) is a relatively rare pregnancy-related thrombotic microangiopathic disorder, usually observed during the third trimester. Its incidence seems to be increased in patients with antiphospholipid syndrome (APS). In this report, we describe a 33-year-old pregnant woman with previously known primary APS who developed early onset HELLP syndrome during the 15th week of gestation. We also review the literature about this interesting relationship between APS and HELLP.
Tsirigotis
Panagiotis
P
2nd Department of Internal Medicine, Propaudeutic, University of Athens, ATTIKON General University Hospital, Athens, Greece. tsiris1@otenet.gr
Mantzios
George
G
Pappa
Vassiliki
V
Girkas
Konstantinos
K
Salamalekis
George
G
Koutras
Angellos
A
Giannopoulou
Vassiliki
V
Spirou
Konstantina
K
Balanika
Alexia
A
Papageorgiou
Sotirios
S
Travlou
Anthi
A
Dervenoulas
John
J
D000028:Abortion, Induced; D000328:Adult; D016736:Antiphospholipid Syndrome / Q000150:complications*; D005260:Female; D020022:Genetic Predisposition to Disease; D005865:Gestational Age; D017359:HELLP Syndrome / Q000209:etiology*; D006801:Humans; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000209:etiology*; D011256:Pregnancy Outcome; D011262:Pregnancy Trimester, Second