Cationic Pd(II)-catalyzed enantioselective cyclization of aroylmethyl 2-alkynoates initiated by carbopalladation of alkynes with arylboronic acids.
A cationic palladium(II)-catalyzed enantioselective intramolecular addition of vinylpalladium species to ketones initiated by the carbopalladation of alkynoates under mild conditions without a Pd(II)/Pd(0) redox system was developed with high yield and enantioselectivity. This cascade reaction provides an efficient method for the construction of optically active hydroxylactones.
Song
Juan
J
Department of Chemistry and Chemical Engineering, Suzhou University, Suzhou, China.
Shen
Qi
Q
Xu
Fan
F
Lu
Xiyan
X