title: Intravitreous vascular endothelial growth factor (VEGF) inhibitor therapy for tamoxifen induced macular edema.
abstract: A 59-year-old male patient with tamoxifen induced macular edema in both eyes was treated with intravitreous sodium pegaptanib. Follow-up clinical examination, OCT, and FA demonstrated reduced edema and leakage with improvement in visual acuity.
authors.affiliation: Jules Stein Eye Institute, Department of Ophthalmology, University of California, Los Angeles, CA 90095, USA. bourla@jsei.ucla.edu
authors.forename: Dan H
authors.initials: DH
authors.lastname: Bourla
authors.forename: Christine R
authors.initials: CR
authors.lastname: Gonzales
authors.forename: Charles W
authors.initials: CW
authors.lastname: Mango
authors.forename: Joel N
authors.initials: JN
authors.lastname: Moral
authors.forename: Robert S
authors.initials: RS
authors.lastname: Wirthlin
authors.forename: Steven D
authors.initials: SD
authors.lastname: Schwartz
mesh_terms: D018931:Antineoplastic Agents, Hormonal / Q000009:adverse effects* / Q000627:therapeutic use; D052157:Aptamers, Nucleotide / Q000008:administration & dosage* / Q000627:therapeutic use; D001254:Astrocytoma / Q000188:drug therapy; D001932:Brain Neoplasms / Q000188:drug therapy; D006801:Humans; D007267:Injections; D008269:Macular Edema / Q000139:chemically induced* / Q000188:drug therapy* / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D013629:Tamoxifen / Q000009:adverse effects* / Q000627:therapeutic use; D016896:Treatment Outcome; D042461:Vascular Endothelial Growth Factor A / Q000037:antagonists & inhibitors*; D014792:Visual Acuity / Q000187:drug effects; D014822:Vitreous Body
chemical_list: D018931:Antineoplastic Agents, Hormonal; D052157:Aptamers, Nucleotide; D042461:Vascular Endothelial Growth Factor A; D013629:Tamoxifen; C495058:pegaptanib