title: [Application of proteomics to diagnosis and treatment of lung cancer].
abstract: With the completion of human genome sequence project (HGP), the application of two-dimensional gel electrophoresis (2-DE), mass spectrometry (MS), and bioinformatics, more achievements have been made in proteomics research. From the new point of view, looking for tumor-specific proteins with proteomics research strategy may help to elucidate the correlation of the change of protein expression to oncogenesis, and may play a vital role in the early detection of cancer and anticancer therapy including drug exploitation. This article briefly reviewed the relevant techniques, strategies, and application of proteomics research on lung cancer.
authors.affiliation: Center of Oncology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong 510515, P. R. China.
authors.forename: Ming
authors.initials: M
authors.lastname: Dai
authors.forename: Rong-Cheng
authors.initials: RC
authors.lastname: Luo
mesh_terms: D014408:Biomarkers, Tumor / Q000378:metabolism; D016503:Drug Delivery Systems; D015180:Electrophoresis, Gel, Two-Dimensional; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis / Q000378:metabolism / Q000628:therapy; D020543:Proteome / Q000378:metabolism*; D040901:Proteomics / Q000379:methods*; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
chemical_list: D014408:Biomarkers, Tumor; D020543:Proteome