Synthesis and antihypertensive effects of new methylthiomorpholinphenol derivatives.
We present in this work the synthesis and cardiovascular effects of new methylthiomorpholine compounds and they were compared with cardiovascular drugs such as captopril, losartan and omapatrilat.
Velázquez
A Ma
AM
División de Ciencias Químico Biológicas, Facultad de Estudios Superiores Cuautitlán, Universidad Nacional Autónoma de México, 54740 Cuautitlán Izcalli, Estado de México, Mexico.
Martínez
L
L
Abrego
V
V
Balboa
M A
MA
Torres
L A
LA
Camacho
B
B
Díaz-Barriga
S
S
Romero
A
A
López-Castañares
R
R
Angeles
E
E
D000818:Animals; D000959:Antihypertensive Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D001794:Blood Pressure / Q000187:drug effects; D004305:Dose-Response Relationship, Drug; D015195:Drug Design; D006339:Heart Rate / Q000187:drug effects; D009025:Morpholines / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D010636:Phenols / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D051381:Rats
D000959:Antihypertensive Agents; D009025:Morpholines; D010636:Phenols