[The reevaluation of neoangiogenesis indices in cutaneous melanoma].
The melanoma today represents one of more diffuse malignant neoplasm and known, object of numerous studies and you debate yourself, topic more and more puts into effect them, observed and estimated under more it varies aspects to you. Our study has been lead taking in consideration the process of neoangiogenesis, fundamental stage in the progression graduates them of the malignant melanoma, than it comes true through the release of VEGF and many other angiogenic molecules from part of the same neoplastic cells. The evolution of such process represents a critical moment for the development of whichever neoplasm, but in particular way in the melanoma it is in charge of the transition from the phase of horizontal increase to that one of vertical increase. We have therefore place the attention on the appraisal of objective indices of the vascularization as factor I prognosticate of the melanoma; particularly way we have correlated the indices of vascularisation in 54 cases of melanomas, all to III the level of Clark, and have obtained of turns out to you that confirm the possibility to insert between the prognostic factors determinants also those.
Marasà
S
S
U.O. Anatomia Patologica ARNAS Civico G. Di Cristina-M. Ascoli, Palermo.
Sciancalepore
G
G
Marasà
L
L
D006801:Humans; D008545:Melanoma / Q000098:blood supply* / Q000401:mortality*; D009389:Neovascularization, Pathologic; D012878:Skin Neoplasms / Q000098:blood supply* / Q000401:mortality*; D015996:Survival Rate