Kaletra single agent HAART after intolerance of NRTI- and NNRTI-containing regimens following kidney transplantation.
We report on a patient who received a diagnosis of HIV infection following kidney transplantation some years earlier. As a result of intolerance and failure of nucleoside and non-nucleoside reverse transcriptase inhibitor (NRTI and NNRTI)-containing regimens, he was started on Kaletra single agent HAART. Kaletra was well tolerated and resulted in sustained viral load suppression below the limit of detection for at least 36 months.
Schürmann
D
D
Dept. of Infectious Diseases and Respiratory Medicine, Charité, Universitätsmedizin Berlin, Augustenburger Platz, Berlin, Germany. dirk.schuermann@charite.de
Wesselmann
H
H
Kurowski
M
M
Suttorp
N
N
Reinke
P
P
D000328:Adult; D023241:Antiretroviral Therapy, Highly Active; D015658:HIV Infections / Q000150:complications / Q000188:drug therapy*; D017320:HIV Protease Inhibitors / Q000627:therapeutic use*; D006801:Humans; D016030:Kidney Transplantation / Q000009:adverse effects; D061466:Lopinavir; D008297:Male; D011744:Pyrimidinones / Q000627:therapeutic use*; D018894:Reverse Transcriptase Inhibitors / Q000009:adverse effects
D017320:HIV Protease Inhibitors; D011744:Pyrimidinones; D018894:Reverse Transcriptase Inhibitors; D061466:Lopinavir