title: Effective monoallylation of anilines catalyzed by supported KF.
abstract: A mild and straightforward monoallylation procedure for different anilines is described using the efficient, inexpensive, noncorrosive, and environmentally friendly reagent KF-Celite. By using only a 1/1.2 stoichiometric ratio of electrophilic reagent to aniline, in very short reaction times, the monoallylated products are obtained in high isolated yields via this procedure, which works very effectively regardless of the electronic nature of the substituent on the ring, although electron withdrawing groups make the reactions go even faster.
authors.affiliation: Organic and Pharmaceutical Chemistry Department, Pharmacy Faculty, Complutense University, 28040-Madrid, Spain.
authors.forename: Vittorio
authors.initials: V
authors.lastname: Pace
authors.forename: Fernando
authors.initials: F
authors.lastname: Martínez
authors.forename: María
authors.initials: M
authors.lastname: Fernández
authors.forename: Jose V
authors.initials: JV
authors.lastname: Sinisterra
authors.forename: Andrés R
authors.initials: AR
authors.lastname: Alcántara
mesh_terms: D000498:Allyl Compounds / Q000138:chemical synthesis*; D000814:Aniline Compounds / Q000138:chemical synthesis*; D002384:Catalysis; D007692:Diatomaceous Earth / Q000737:chemistry*; D007202:Indicators and Reagents; D007700:Kinetics; D012997:Solvents; D013237:Stereoisomerism; D013696:Temperature
chemical_list: D000498:Allyl Compounds; D000814:Aniline Compounds; D007202:Indicators and Reagents; D012997:Solvents; D007692:Diatomaceous Earth