title: ProSight PTM 2.0: improved protein identification and characterization for top down mass spectrometry.
abstract: ProSight PTM 2.0 (http://prosightptm2.scs.uiuc.edu) is the next generation of the ProSight PTM web-based system for the identification and characterization of proteins using top down tandem mass spectrometry. It introduces an entirely new data-driven interface, integrated Sequence Gazer for protein characterization, support for fixed modifications, terminal modifications and improved support for multiple precursor ions (multiplexing). Furthermore, it supports data import and export for local analysis and collaboration.
authors.affiliation: Department of Chemistry, University of Illinois, Urbana, IL 61801, USA.
authors.forename: Leonid
authors.initials: L
authors.lastname: Zamdborg
authors.forename: Richard D
authors.initials: RD
authors.lastname: LeDuc
authors.forename: Kevin J
authors.initials: KJ
authors.lastname: Glowacz
authors.forename: Yong-Bin
authors.initials: YB
authors.lastname: Kim
authors.forename: Vinayak
authors.initials: V
authors.lastname: Viswanathan
authors.forename: Ian T
authors.initials: IT
authors.lastname: Spaulding
authors.forename: Bryan P
authors.initials: BP
authors.lastname: Early
authors.forename: Eric J
authors.initials: EJ
authors.lastname: Bluhm
authors.forename: Shannee
authors.initials: S
authors.lastname: Babai
authors.forename: Neil L
authors.initials: NL
authors.lastname: Kelleher
mesh_terms: D019295:Computational Biology / Q000379:methods*; D030562:Databases, Protein; D001330:Electronic Data Processing; D006801:Humans; D020407:Internet; D013058:Mass Spectrometry / Q000379:methods*; D011110:Polymorphism, Genetic; D011381:Programming Languages; D011499:Protein Processing, Post-Translational; D011506:Proteins / Q000032:analysis / Q000737:chemistry* / Q000235:genetics; D020539:Sequence Analysis, Protein; D016324:Sequence Tagged Sites; D012984:Software; D014584:User-Computer Interface
chemical_list: D011506:Proteins