title: Dual action-based approaches to antibacterial agents.
abstract: This review collates and analyses recent work done on dual action approaches to tackling the mounting health problem of resistance by human pathogenic bacteria to antibacterial agents. In particular the areas reviewed include the use of two drugs in combination, dual action prodrugs, and dual action drugs (or hybrid drugs).
authors.affiliation: Department of Chemistry, University of Wollongong, Wollongong, NSW, 2522, Australia. john_bremner@uow.edu.au
authors.forename: John B
authors.initials: JB
authors.lastname: Bremner
authors.forename: Joseph I
authors.initials: JI
authors.lastname: Ambrus
authors.forename: Siritron
authors.initials: S
authors.lastname: Samosorn
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000493:pharmacokinetics / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects; D008958:Models, Molecular; D011355:Prodrugs; D013329:Structure-Activity Relationship
chemical_list: D000900:Anti-Bacterial Agents; D011355:Prodrugs