Motor outcome according to diffusion tensor tractography findings in the early stage of intracerebral hemorrhage.
We tried to investigate the motor outcome according to diffusion tensor tractography (DTT) findings for the corticospinal tract (CST) in the early stage for hemiparetic patients with intracerebral hemorrhage (ICH). Forty patients with severe paralysis of the affected side were enrolled. DTT was obtained in the early stage of the stroke (7-30 days) and was classified into four groups: type A, the CST originating from primary motor cortex was preserved around the hematoma; type B, the CST was similar to type A except the fiber originated from the adjacent areas to the primary motor cortex; type C, the CST was interrupted at or around the hematoma; and type D, the CST did not reach the hematoma due to degeneration (Fig. 1). Six months after onset, motor function was measured and the statistical influence of the DTT type was tested. Initially, none of the motor function scales of the affected side differed among the four DTT types. Six months after the onset of ICH, motor functions of the same side were significantly different according to DTT type (p<0.05). All motor scales were highest in the DTT type A group, and were lowest in the DTT type D group (p<0.0003). The early DTT findings for CST may be used to predict the motor outcome of the affected extremities in hemiparetic patients with ICH.
Cho
Sang-Hyun
SH
Department of Physical Therapy, Institute of Health Science, Yonsei University College of Health Science, Daemyungdong, Namku, Taegu 705-717, Republic of Korea.
Kim
Seong Ho
SH
Choi
Byung Yun
BY
Cho
Soo Ho
SH
Kang
Jae Hoon
JH
Lee
Chu-Hee
CH
Byun
Woo Mok
WM
Jang
Sung Ho
SH
D000328:Adult; D001931:Brain Mapping; D002543:Cerebral Hemorrhage / Q000473:pathology* / Q000503:physiopathology*; D016009:Chi-Square Distribution; D038524:Diffusion Magnetic Resonance Imaging; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008297:Male; D008875:Middle Aged; D009043:Motor Activity / Q000502:physiology*; D011597:Psychomotor Performance; D011712:Pyramidal Tracts / Q000473:pathology*; D020127:Recovery of Function