title: Evaluating the optic disc and retinal nerve fiber layer in glaucoma. I: Clinical examination and photographic methods.
abstract: Glaucoma is a leading cause of blindness worldwide and is characterized in part by specific changes in the optic disc and retinal nerve fiber layer. Currently, subjective clinical examination and fundus photography are the most common ways of detecting structural change in glaucoma and monitoring its progression. In the first part of this two-part article, the authors overview structural changes of the optic disc and retinal nerve fiber layer in glaucoma and describe and evaluate photographic methods for observing these changes. In the second part of this article (this issue), recent developments in computer-based optical imaging techniques that allow objective evaluation of the optic disc and retinal nerve fiber layer are described.
authors.affiliation: Department of Ophthalmology, Glaucoma Center and Diagnostic Imaging Laboratory, University of California at San Diego, La Jolla, CA 92093-0946, USA.
authors.forename: C
authors.initials: C
authors.lastname: Bowd
authors.forename: R N
authors.initials: RN
authors.lastname: Weinreb
authors.forename: L M
authors.initials: LM
authors.lastname: Zangwill
mesh_terms: D003941:Diagnostic Techniques, Ophthalmological; D005901:Glaucoma / Q000175:diagnosis*; D006801:Humans; D009412:Nerve Fibers / Q000473:pathology*; D009898:Optic Disk / Q000473:pathology*; D009901:Optic Nerve Diseases / Q000175:diagnosis*; D010781:Photography / Q000379:methods*; D012165:Retinal Ganglion Cells / Q000473:pathology*