title: Chronic daily headache in hereditary hemochromatosis treated by venesection.
abstract: Coincidence or causality between iron overload and headaches (e.g., daily headache, migraine, and cluster headache) is still under discussion. Herein we report a patient suffering from hereditary hemochromatosis (homozygous C282Y mutation; OMIM: 235220, Locus 6p21.3) and daily headache fulfilling the IHSD-2 criteria of chronic migraine. Three treatments by venesection improved the headache substantially in frequency, intensity, and duration of attacks. We suggest treatment by venesection for iron depletion in patients suffering from hemochromatois and headache.
authors.forename: Charly
authors.initials: C
authors.lastname: Gaul
authors.forename: Patrick
authors.initials: P
authors.lastname: Krummernerl
authors.forename: Beate
authors.initials: B
authors.lastname: Tamke
authors.forename: Malte
authors.initials: M
authors.lastname: Kornhuber
mesh_terms: D000328:Adult; D005260:Female; D020773:Headache Disorders / Q000150:complications* / Q000628:therapy*; D006432:Hemochromatosis / Q000150:complications* / Q000628:therapy*; D006801:Humans; D018962:Phlebotomy