Chronic intestinal pseudo-obstruction: manifestations, natural history and management.
Chronic intestinal pseudo-obstruction (CIPO) is a rare pathological condition characterized by a marked derangement of gut propulsive motility mimicking mechanical obstruction, in the absence of any lesion occluding the gut lumen. This disease is often associated with a disabling and potentially life-threatening complications and is still too often unrecognized even in referral centres. As a result, patients receive neither appropriate care nor recognition of their severe health condition. Medical and surgical therapies are often unsatisfactory and long-term outcome turns out to be poor in the vast majority of cases. This article focuses on the main clinical features, the management and long-term outcome of patients affected by CIPO, with particular emphasis on those aspects which remain a matter of debate.
Stanghellini
V
V
Department of Internal Medicine and Gastroenterology, University of Bologna, Bologna, Italy. v.stanghellini@unibo.it
Cogliandro
R F
RF
de Giorgio
R
R
Barbara
G
G
Salvioli
B
B
Corinaldesi
R
R
D002908:Chronic Disease; D013505:Digestive System Surgical Procedures; D016145:Endoscopy, Digestive System; D005765:Gastrointestinal Agents / Q000627:therapeutic use; D005769:Gastrointestinal Motility; D006801:Humans; D007418:Intestinal Pseudo-Obstruction / Q000175:diagnosis* / Q000628:therapy*; D008365:Manometry
D005765:Gastrointestinal Agents