Vaterite deposition on biodegradable polymer foam scaffolds for inducing bone-like hydroxycarbonate apatite coatings.
Hydroxycarbonate apatite (HCA) coatings on the surface of bioresorbable materials for bone tissue engineering scaffolds were produced using macroporous poly(DL-lactide) (PDLLA) foams impregnated by calcium carbonate in vaterite crystalline form. Stable and homogeneous vaterite deposition on PDLLA foams was achieved using a slurry dipping technique. In vitro studies in simulated body fluid (SBF) were performed to induce formation of (HCA) on the surface of vaterite/PDLLA composite foams. HCA was detected after immersion of foams in SBF for 7 days. Hence, depositing vaterite on materials followed by immersion in SBF is confirmed to induce HCA coatings on the surface of the material. The HCA coated, bioactive and resorbable PDLLA foams are intended for use as bone tissue engineering scaffolds.
Maeda
H
H
Department of Materials Science and Engineering, Graduate School of Engineering, Nagoya Institute of Technology, Nagoya 466-8555, Japan.
Maquet
V
V
Kasuga
T
T
Chen
Q Z
QZ
Roether
J A
JA
Boccaccini
A R
AR
D020341:Absorbable Implants; D001031:Apatites / Q000737:chemistry*; D018786:Bone Substitutes / Q000138:chemical synthesis* / Q000737:chemistry; D002119:Calcium Carbonate / Q000737:chemistry*; D002254:Carbonates / Q000737:chemistry*; D011232:Chemical Precipitation; D020099:Coated Materials, Biocompatible / Q000138:chemical synthesis* / Q000737:chemistry; D008855:Microscopy, Electron, Scanning; D011091:Polyesters / Q000737:chemistry; D011108:Polymers / Q000737:chemistry; D016062:Porosity; D023822:Tissue Engineering; D054457:Tissue Scaffolds; D014961:X-Ray Diffraction
D001031:Apatites; D018786:Bone Substitutes; D002254:Carbonates; D020099:Coated Materials, Biocompatible; D011091:Polyesters; D011108:Polymers; C413465:hydroxycarbonate apatite; C033616:poly(lactide); D002119:Calcium Carbonate