title: Cutaneous vasculitis as a paraneoplastic syndrome in childhood.
abstract: BACKGROUND
  In children, vasculitis as a paraneoplastic syndrome has never been reported before. In this work we report a vasculitis syndrome as a neoplasm onset manifestation in a child and we discuss our case regarding the data from literature.
  
  
  METHODS
  A 7-year-old girl presented with hand and foot ulceration, fixed cyanosis and pallor. During investigation, a central nervous system (CNS) rhabdomyosarcoma with metastasis on multiple sites was diagnosed.
  
  
  CONCLUSIONS
  Rhabdomyosarcomas represent 5 to 8% of child neoplasms, although the CNS seldom is the primary site. In the indexed English language literature there were no published cases of vasculitis associated with rhabdomyosarcoma as a paraneoplastic syndrome in childhood, which suggests that the described report is the first being published. Awareness of this possible coexistence could allow to an earlier diagnosis of neoplasms expressed by vasculitis, leading to an earlier treatment and a longer survival.
authors.affiliation: Medica Pediatra, Especializacao em Reumatologia Pediatrica, Instituto de Puericultura e Pediatria Martagao Gesteira, Universidade Federal do Rio de Janeiro, Brasil. chrispelajo@oi.com.br
authors.forename: Christina Feitosa
authors.initials: CF
authors.lastname: Pelajo
authors.forename: Sheila Knupp Feitosa
authors.initials: SK
authors.lastname: de Oliveira
authors.forename: Marta Cristine
authors.initials: MC
authors.lastname: Rodrigues
authors.forename: Juliana Maia
authors.initials: JM
authors.lastname: Torres
mesh_terms: D001932:Brain Neoplasms / Q000150:complications* / Q000175:diagnosis*; D002648:Child; D005260:Female; D006801:Humans; D010257:Paraneoplastic Syndromes / Q000175:diagnosis*; D012208:Rhabdomyosarcoma / Q000150:complications* / Q000175:diagnosis*; D012867:Skin / Q000098:blood supply*; D014657:Vasculitis / Q000209:etiology*