title: [Bartonella infection in hematological practice].
abstract: OBJECTIVE
  To characterize the clinical and histological features of Bartonella infection in patients asking for hematological advice and to assess the significance of serological and molecular methods for the diagnosis of this infection.
  
  
  METHODS
  The case histories of 747 patients asking for advice at the Hematology Research Cancer, Russian Academy of Medical Sciences, for lymphadenopaphy were retrospectively studied. The study included 10 patients in whom Bartonella infection could be suspected. For verification of the diagnosis, the authors conducted a serological study of the patients' sera and a molecular study of archival paraffined lymph node biopsy specimens.
  
  
  RESULTS
  The study showed it possible to make a retrospective diagnosis of cat-scratch disease (CSD) by polymerase chain reaction (PCR) used in the study of archival lymph node biopsy specimens and stained preparations.
  
  
  CONCLUSIONS
  CSD should be suspected when a patient has sustained lymphadenopathy and a respective epidemiological history (feline contact). Bartonella infection should be diagnosed on the basis of a dynamic serological study and, if possible, PCR of cells from biopsy specimens of lymph nodes or the lesion developed at the site of Bartonella penetration into the human body (primary affect).
authors.forename: A L
authors.initials: AL
authors.lastname: Melikian
authors.forename: O Iu
authors.initials: OIu
authors.lastname: Mediannikov
authors.forename: I B
authors.initials: IB
authors.lastname: Kaplanskaia
authors.forename: A I
authors.initials: AI
authors.lastname: Komarova
authors.forename: I V
authors.initials: IV
authors.lastname: Tarasevich
mesh_terms: D000293:Adolescent; D000328:Adult; D000907:Antibodies, Bacterial / Q000097:blood; D001474:Bartonella Infections / Q000097:blood / Q000175:diagnosis / Q000473:pathology; D018416:Bartonella henselae / Q000235:genetics / Q000276:immunology / Q000302:isolation & purification*; D018413:Bartonella quintana / Q000235:genetics / Q000276:immunology / Q000302:isolation & purification*; D004269:DNA, Bacterial / Q000235:genetics; D003937:Diagnosis, Differential; D005260:Female; D006405:Hematology; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology; D008297:Male; D008875:Middle Aged; D016133:Polymerase Chain Reaction; D012189:Retrospective Studies; D014205:Trench Fever / Q000097:blood / Q000175:diagnosis / Q000473:pathology
chemical_list: D000907:Antibodies, Bacterial; D004269:DNA, Bacterial