Mesenteric vein thrombosis associated with primary cytomegalovirus infection: a case report.
In the past few years several studies have supported an interplay between cytomegalovirus infections and a prothrombotic state. We describe a case of primary cytomegalovirus infection in an immunocompetent adult that was complicated with mesenteric vein thrombosis. Transient protein C deficiency, lupus anticoagulant and activated protein C resistance were found, in combination with a heterozygous prothrombin G20210A mutation. We discuss the possible mechanisms of cytomegalovirus-related venous thrombosis.
Lijfering
Willem M
WM
Division of Haemostasis, Thrombosis and Rheology, University Medical Center Groningen, Groningen, The Netherlands. w.lijfering@int.umcg.nl
Sprenger
Herman G
HG
van Son
Willem J
WJ
van der Meer
Jan
J
D020016:Activated Protein C Resistance / Q000097:blood / Q000209:etiology* / Q000235:genetics; D000328:Adult; D019943:Amino Acid Substitution; D003586:Cytomegalovirus Infections / Q000097:blood / Q000150:complications* / Q000235:genetics; D005260:Female; D006801:Humans; D016682:Lupus Coagulation Inhibitor / Q000097:blood; D008642:Mesenteric Veins / Q000821:virology; D020125:Mutation, Missense; D020151:Protein C Deficiency / Q000097:blood / Q000209:etiology* / Q000235:genetics; D011516:Prothrombin / Q000032:analysis / Q000235:genetics; D020246:Venous Thrombosis / Q000097:blood / Q000209:etiology* / Q000235:genetics
D016682:Lupus Coagulation Inhibitor; D011516:Prothrombin