title: Complete genome sequence of the fish pathogen Flavobacterium psychrophilum.
abstract: We report here the complete genome sequence of the virulent strain JIP02/86 (ATCC 49511) of Flavobacterium psychrophilum, a widely distributed pathogen of wild and cultured salmonid fish. The genome consists of a 2,861,988-base pair (bp) circular chromosome with 2,432 predicted protein-coding genes. Among these predicted proteins, stress response mediators, gliding motility proteins, adhesins and many putative secreted proteases are probably involved in colonization, invasion and destruction of the host tissues. The genome sequence provides the basis for explaining the relationships of the pathogen to the host and opens new perspectives for the development of more efficient disease control strategies. It also allows for a better understanding of the physiology and evolution of a significant representative of the family Flavobacteriaceae, whose members are associated with an interesting diversity of lifestyles and habitats.
authors.affiliation: INRA, Unité Virologie et Immunologie Moléculaires UR892, F-78350 Jouy-en-Josas, France. eric.duchaud@jouy.inra.fr
authors.forename: Eric
authors.initials: E
authors.lastname: Duchaud
authors.forename: Mekki
authors.initials: M
authors.lastname: Boussaha
authors.forename: Valentin
authors.initials: V
authors.lastname: Loux
authors.forename: Jean-François
authors.initials: JF
authors.lastname: Bernardet
authors.forename: Christian
authors.initials: C
authors.lastname: Michel
authors.forename: Brigitte
authors.initials: B
authors.lastname: Kerouault
authors.forename: Stanislas
authors.initials: S
authors.lastname: Mondot
authors.forename: Pierre
authors.initials: P
authors.lastname: Nicolas
authors.forename: Robert
authors.initials: R
authors.lastname: Bossy
authors.forename: Christophe
authors.initials: C
authors.lastname: Caron
authors.forename: Philippe
authors.initials: P
authors.lastname: Bessières
authors.forename: Jean-François
authors.initials: JF
authors.lastname: Gibrat
authors.forename: Stéphane
authors.initials: S
authors.lastname: Claverol
authors.forename: Fabien
authors.initials: F
authors.lastname: Dumetz
authors.forename: Michel
authors.initials: M
authors.lastname: Le Hénaff
authors.forename: Abdenour
authors.initials: A
authors.lastname: Benmansour
mesh_terms: D000818:Animals; D018441:Biofilms; D001709:Biotechnology / Q000379:methods*; D002448:Cell Adhesion; D002462:Cell Membrane / Q000378:metabolism; D005399:Fishes / Q000382:microbiology*; D045826:Flavobacteriaceae Infections / Q000378:metabolism; D005417:Flavobacterium / Q000378:metabolism*; D016678:Genome; D016680:Genome, Bacterial; D008954:Models, Biological; D016366:Open Reading Frames; D010271:Parasites