title: Pathogenesis of Parkinson's disease: oxidative stress, environmental impact factors and inflammatory processes.
abstract: Current hypothesis of neuronal degeneration in Parkinson's disease (PD) have been proposed, including formation of free radicals and oxidative stress, mitochondrial dysfunction, excitotoxicity, trophic factor deficiency, inflammatory processes, genetic factors, environmental impact factors, toxic action of nitric oxide, apoptosis, and so on. This review mainly discussed oxidative stress, environmental impact factors, and inflammatory processes in PD.
authors.affiliation: Department of Integrated Traditional Chinese and Western Medicine, the General Hospital of Chinese People's Armed Police Forces, Beijing 100039, China. hongyuan6@yahoo.com
authors.forename: Hong
authors.initials: H
authors.lastname: Yuan
authors.forename: Jing-Chen
authors.initials: JC
authors.lastname: Zheng
authors.forename: Ping
authors.initials: P
authors.lastname: Liu
authors.forename: Shao-Feng
authors.initials: SF
authors.lastname: Zhang
authors.forename: Jian-Yang
authors.initials: JY
authors.lastname: Xu
authors.forename: Li-Min
authors.initials: LM
authors.lastname: Bai
mesh_terms: D000818:Animals; D004785:Environmental Pollutants / Q000009:adverse effects*; D006801:Humans; D007249:Inflammation / Q000276:immunology; D018384:Oxidative Stress / Q000276:immunology*; D010300:Parkinson Disease / Q000276:immunology* / Q000503:physiopathology
chemical_list: D004785:Environmental Pollutants