Peptide YY producing strumal carcinoid of the ovary as the cause of severe constipation with contralateral epithelial ovarian cancer.
Primary ovarian carcinoid tumors are rare. It has been reported that constipation was a presenting symptom in some patients with ovarian carcinoid. A case of strumal carcinoid of the ovary with contralateral clear cell adenocarcinoma of the ovary discovered with a complaint of constipation is described. Constipation was dramatically improved by resectioning the tumor. The tumor cells were positive for peptide YY (PYY) in the carcinoid component, but not in any other components. The present case could provide evidence of the correlation between constipation and PYY that has been reported elsewhere. Interestingly, the constipation caused by PYY also helped in discovering epithelial ovarian cancer.
Kawano
Kouichiro
K
Department of Obstetrics and Gynecology, Kurume University, School of Medicine, Kurume, Fukuoka, Japan. kkawano@mbp.ocn.ne.jp
Ushijima
Kimio
K
Fujimoto
Takefumi
T
Komai
Kan
K
Kamura
Toshiharu
T
D018262:Adenocarcinoma, Clear Cell / Q000150:complications* / Q000473:pathology; D002276:Carcinoid Tumor / Q000150:complications / Q000378:metabolism* / Q000473:pathology; D003248:Constipation / Q000209:etiology* / Q000378:metabolism; D005260:Female; D006801:Humans; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000150:complications / Q000378:metabolism / Q000473:pathology; D010051:Ovarian Neoplasms / Q000150:complications / Q000378:metabolism* / Q000473:pathology; D010053:Ovary / Q000473:pathology; D019894:Peptide YY / Q000378:metabolism*
D019894:Peptide YY