Double resistance to imatinib and AMG 706 caused by multiple acquired KIT exon 17 mutations in a gastrointestinal stromal tumour.
Grabellus
Florian
F
Ebeling
Peter
P
Worm
Karl
K
Sheu
Sien-Yi
SY
Antoch
Gerald
G
Frilling
Andrea
A
Schmid
Kurt W
KW
D001483:Base Sequence; D001549:Benzamides; D018432:Drug Resistance, Multiple / Q000235:genetics; D019008:Drug Resistance, Neoplasm / Q000235:genetics; D005260:Female; D046152:Gastrointestinal Stromal Tumors / Q000188:drug therapy*; D006801:Humans; D000068877:Imatinib Mesylate; D007211:Indoles / Q000627:therapeutic use*; D008875:Middle Aged; D009536:Niacinamide / Q000031:analogs & derivatives* / Q000627:therapeutic use; D009841:Oligonucleotides; D010879:Piperazines / Q000627:therapeutic use*; D017354:Point Mutation; D019009:Proto-Oncogene Proteins c-kit / Q000235:genetics*; D011743:Pyrimidines / Q000627:therapeutic use*
D001549:Benzamides; D007211:Indoles; D009841:Oligonucleotides; D010879:Piperazines; D011743:Pyrimidines; D009536:Niacinamide; D000068877:Imatinib Mesylate; D019009:Proto-Oncogene Proteins c-kit; C519562:imetelstat