title: [Comparison of safety and sensitivity in diagnosis of liver lesion between ultrasound-guided 16 gauges and 18 gauges core needle biopsy].
abstract: OBJECTIVE
  To compare safety and sensitivity in diagnosis of liver lesion between ultrasound-guided 16 gauges (G) and 18 G core needle biopsy.
  
  
  METHODS
  Ultrasound-guided 16 G needle biopsy was performed in 141 patients, 77 males and 64e females, aged 51.2, and ultrasound-guided 18 G needle biopsy was performed in 105 patients, 54 males and 51 females, aged 60.1. The final diagnosis was based on the post-operative pathological examination and/or the results of 6-month follow-up.
  
  
  RESULTS
  In the In the ultrasound-guided 16 G needle biopsy, 171 passes were performed with an average of 1.21 pass, a sensitivity rate of 95.9%, and a specificity rate of 100%, and abdominal pain occurred in 51 cases, and bleeding occurred in 3 cases. In the ultrasound-guided 18 G needle biopsy, 161 passes were performed with an average of 1.53 passes, a sensitivity rate of 83.8%, and a specificity rate of 100%, and abdominal pain occurred in 37 cases, and bleeding occurred in 2 cases. The number of pass of the 16 G was significantly less then that of the 128 G group (P = 0.000). The sensitivity rate of the 16 G needle biopsy was significantly higher than that of the 18 G group (P = 0.46).
  
  
  CONCLUSIONS
  Ultrasound-guided 16 gauges core needle biopsy is safe for the diagnosis of hepatic disease and more sensitive than the 18 G biopsy.
authors.affiliation: Department of Diagnostic Ultrasound, Peking University First Hospital, Beijing 100034, China.
authors.forename: Fei
authors.initials: F
authors.lastname: Chen
authors.forename: Bin
authors.initials: B
authors.lastname: Wang
authors.forename: Lu-zeng
authors.initials: LZ
authors.lastname: Chen
mesh_terms: D015746:Abdominal Pain / Q000209:etiology; D001707:Biopsy, Needle / Q000009:adverse effects / Q000295:instrumentation / Q000379:methods; D005260:Female; D006470:Hemorrhage / Q000209:etiology; D006801:Humans; D008099:Liver / Q000000981:diagnostic imaging / Q000473:pathology; D008113:Liver Neoplasms / Q000175:diagnosis* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D018084:Ultrasonography, Interventional / Q000009:adverse effects / Q000379:methods*