Slit diaphragm junctional complex and regulation of the cytoskeleton.
In recent years, identification of proteins found at the slit diaphragm has greatly improved our understanding of the molecular mechanisms responsible for forming and maintaining the glomerular filtration barrier. This review examines the function of proteins identified at the podocyte intercellular junction in coordinating podocyte intercellular junction dynamics or cytoskeletal dynamics.
Garg
Puneet
P
Division of Nephrology, University of Michigan Medical School, Ann Arbor, MI 48109-0676, USA.
Verma
Rakesh
R
Holzman
Lawrence B
LB
D000818:Animals; D003598:Cytoskeletal Proteins / Q000378:metabolism*; D003599:Cytoskeleton / Q000378:metabolism*; D004847:Epithelial Cells / Q000378:metabolism*; D050533:Glomerular Basement Membrane / Q000378:metabolism*; D006801:Humans; D007365:Intercellular Junctions / Q000378:metabolism*; D008565:Membrane Proteins / Q000378:metabolism*; D050199:Podocytes / Q000378:metabolism*
D003598:Cytoskeletal Proteins; D008565:Membrane Proteins