title: One-pot amidation of olefins through Pd-catalyzed coupling of alkylboranes and carbamoyl chlorides.
abstract: A one-pot synthesis of C1-elongated amides starting from olefins and carbamoyl chlorides has been developed. Alkylboranes, generated by hydroboration of terminal olefins with 9-BBN-H, underwent smooth coupling with carbamoyl chlorides in the presence of palladium catalyst and Cs2CO3.
authors.affiliation: Graduate School of Pharmaceutical Sciences, Kyoto University, Yoshida, Sakyo-ku, Kyoto 606-8501, Japan.
authors.forename: Yoshizumi
authors.initials: Y
authors.lastname: Yasui
authors.forename: Sayo
authors.initials: S
authors.lastname: Tsuchida
authors.forename: Hideto
authors.initials: H
authors.lastname: Miyabe
authors.forename: Yoshiji
authors.initials: Y
authors.lastname: Takemoto
mesh_terms: D000475:Alkenes / Q000737:chemistry*; D000577:Amides / Q000737:chemistry*; D001880:Boranes / Q000737:chemistry*; D002384:Catalysis; D002712:Chlorides / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry*
chemical_list: D000475:Alkenes; D000577:Amides; D001880:Boranes; D002712:Chlorides; D010165:Palladium