title: Acral arteriovenous tumor (cirsoid aneurysm): clinical and histopathological analysis of 6 cases.
abstract: OBJECTIVE
  The aim of this study is to have a further insight into this vascular tumor both clinically and histopathologically.
  
  
  METHODS
  We examined 6 cases of acral arteriovenous tumor. Histochemically Masson trichrom, elastic van Gieson and immunohistochemically Desmin, Factor VIII, S100 and Mast cell tryptase were applied to the paraffin sections to evaluate the content of the vessels and mast cell distribution within the lesion.
  
  
  RESULTS
  Vessels had smooth muscle and laminae elastica in most of the lesions. Arteriovenous anastomosis and glomus cells were not detected in any of the lesions. Mast cell count in the lesion was 215.17+/-42.2 whereas in control cases it was 89.16+/- 28.44. (p<0.001)
  
  
  CONCLUSIONS
  We suggest that acral arteriovenous tumor is an arterial and venous originated neoplasm, not an embryonic remnant or an aneurysm.
authors.affiliation: Kocaeli University Medical School Department of Pathology Kocaeli, Turkey.
authors.forename: Yesim
authors.initials: Y
authors.lastname: Gurbuz
authors.forename: Bahar
authors.initials: B
authors.lastname: Muezzinoglu
authors.forename: Rebiay
authors.initials: R
authors.lastname: Apaydin
authors.forename: A Zuhal
authors.initials: AZ
authors.lastname: Yumbul
mesh_terms: D000293:Adolescent; D000328:Adult; D001164:Arteriovenous Fistula / Q000378:metabolism / Q000473:pathology*; D003893:Desmin / Q000378:metabolism; D005169:Factor VIII / Q000378:metabolism; D005260:Female; D006391:Hemangioma / Q000378:metabolism / Q000473:pathology*; D006801:Humans; D008297:Male; D008407:Mast Cells; D008875:Middle Aged; D009383:Neoplasms, Vascular Tissue / Q000378:metabolism / Q000473:pathology*; D009418:S100 Proteins / Q000378:metabolism; D053802:Tryptases / Q000378:metabolism
chemical_list: D003893:Desmin; D009418:S100 Proteins; D005169:Factor VIII; D053802:Tryptases