title: [Rocky Mountain spotted fever in children: clinical and epidemiological features].
abstract: OBJECTIVE
  To report the clinical features of the Rocky Mountain spotted fever (RMSF) in children of southern Sonora, Mexico.
  
  
  METHODS
  Nine cases were studied at the Sonora State Children's Hospital. One case was defined by clinical features and positive serological tests (indirect immunofluorescence assay or reaction to Proteus OX 19). Demographic and clinical characteristics of the patients were registered.
  
  
  RESULTS
  The study subjects were children from two to twelve years ofage. All patients have had contact with tick-infested dogs and had fever, as well as petechial rash. Laboratory findings included high levels of hepatic aminotransferase, hyponatremia and thrombocytopenia. Therapy with chloramphenicol and doxyciclyne was administered after the first seven days of the onset of illness. The mortality rate was 22%.
  
  
  CONCLUSIONS
  This study supports the presence of RMSF in the state of Sonora, Mexico, which should be considered as a public health hazard, requiring immediate actions for prevention and control.
authors.affiliation: Servicio de Urgencias y Consulta Externa, Hospital Infantil del Estado de Sonora, Hermosillo, Son., México.
authors.forename: Miguel Angel
authors.initials: MA
authors.lastname: Martínez-Medina
authors.forename: Gerardo
authors.initials: G
authors.lastname: Alvarez-Hernández
authors.forename: José Guillermo
authors.initials: JG
authors.lastname: Padilla-Zamudioa
authors.forename: Maria Guadalupe
authors.initials: MG
authors.lastname: Rojas-Guerra
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001733:Bites and Stings / Q000150:complications; D002648:Child; D002675:Child, Preschool; D002701:Chloramphenicol / Q000627:therapeutic use; D004285:Dogs / Q000469:parasitology; D004318:Doxycycline / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008297:Male; D008800:Mexico / Q000453:epidemiology; D012373:Rocky Mountain Spotted Fever / Q000175:diagnosis* / Q000188:drug therapy / Q000401:mortality; D013987:Ticks
chemical_list: D000900:Anti-Bacterial Agents; D002701:Chloramphenicol; D004318:Doxycycline