title: [Acral myxoinflammatory fibroblastic sarcoma: a report of two cases].
abstract: Acral myxoinflammatory fibroblastic sarcoma is a rare low-grade malignant soft tissue tumor, usually observed in the extremities of middle-aged adults. We report two cases which occurred in the thumb and knee of middle-aged women. Both tumors showed a multinodular architecture, with cellular areas, occasional foci of hyalinized fibrosis, and hypocellular areas with a myxoid background. Various neoplastic cells were identified including spindled or rounded epithelioid cells and occasional bizarre giant cells, morphologically mimicking Reed-Sternberg cells or ganglion cells. Tumor cells were strongly immunoreactive for vimentin, and variably positive for CD68 and CD34. Both tumors were completely resected and patients were free of disease without any further treatment after a mean follow-up of 14 months.
authors.affiliation: Service d'Anatomie Pathologique, Centre Hospitalier Universitaire, 4, rue Larrey, 49993 Angers Cedex 9. maud.brousseau@gmail.com
authors.forename: Maud
authors.initials: M
authors.lastname: Brousseau
authors.forename: Gérard
authors.initials: G
authors.lastname: Bertrand
authors.forename: Eric
authors.initials: E
authors.lastname: Lavoine
authors.forename: Sami
authors.initials: S
authors.lastname: Kettani
authors.forename: Fabrice
authors.initials: F
authors.lastname: Rabarin
authors.forename: Yann
authors.initials: Y
authors.lastname: Saint-Cast
authors.forename: Philippe
authors.initials: P
authors.lastname: Massin
authors.forename: Marie-Christine
authors.initials: MC
authors.lastname: Rousselet
mesh_terms: D015703:Antigens, CD / Q000032:analysis; D018952:Antigens, CD34 / Q000032:analysis; D015214:Antigens, Differentiation, Myelomonocytic / Q000032:analysis; D005260:Female; D006801:Humans; D007249:Inflammation; D018208:Liposarcoma, Myxoid / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D000097382:CD68 Molecule
chemical_list: D015703:Antigens, CD; D018952:Antigens, CD34; D015214:Antigens, Differentiation, Myelomonocytic; C067980:CD68 antigen, human; D000097382:CD68 Molecule