title: [Urine specific gravity during general anesthesia].
abstract: BACKGROUND
  The urine volume and urine specific gravity per unit time during a short operation under volume loading were examined to explore the possibility of urine specific gravity as an indirect index of fluid therapy.
  
  
  METHODS
  After introducing anesthesia, under volume loading with acetic acid Ringer solution 10 ml x kg(-1) x hr(-1), urine volume and specific gravity per unit time at 30 min intervals from urination to 90 min later and the correlation between the urine volume and urine specific gravity were examined. A chronological increase of urine specific gravity was also confirmed. Therefore, the values of urine specific gravity of each 30 minute intervals were compared using Student's t-test.
  
  
  RESULTS
  The urine volume and urine specific gravity per unit time showed no significant negative correlation until after 90 min. Increasing urine specific gravity even under volume loading became significant 90 min after urination.
  
  
  CONCLUSIONS
  There is a possibility of employing urine specific gravity as an indirect index of fluid therapy.
authors.affiliation: Department of Anesthesiology, Tokyo Women's Medical University, Tokyo.
authors.forename: Maho
authors.initials: M
authors.lastname: Kinoshita
authors.forename: Nobutada
authors.initials: N
authors.lastname: Morioka
authors.forename: Chisato
authors.initials: C
authors.lastname: Nozaki
authors.forename: Mikiko
authors.initials: M
authors.lastname: Abe
authors.forename: Arata
authors.initials: A
authors.lastname: Yamada
authors.forename: Makoto
authors.initials: M
authors.lastname: Ozaki
mesh_terms: D000328:Adult; D000368:Aged; D000768:Anesthesia, General; D005260:Female; D005440:Fluid Therapy; D006801:Humans; D007552:Isotonic Solutions / Q000008:administration & dosage; D008297:Male; D008875:Middle Aged; D016343:Monitoring, Intraoperative; D013046:Specific Gravity; D014556:Urine
chemical_list: D007552:Isotonic Solutions; C028570:Ringer's acetate