Current role of capillary electrophoretic/electrokinetic techniques in forensic toxicology.
The current application of capillary electrophoresis in forensic toxicology has been critically reviewed with special focus on the areas where this technique has shown real advantages over chromatographic methods. For example, capillary electrophoresis has been most successfully applied to the chiral analysis of some drugs of forensic interest, including amphetamines and their congeners. Another typical application field of capillary electrophoresis is represented by protein analysis. Recently, special interest has been paid to carbohydrate deficient transferrin (CDT), the most important biological marker of chronic alcohol abuse. Other specific applications of capillary electrophoresis of potential forensic toxicological concern are also discussed. The review includes 62 references.
Tagliaro
Franco
F
Department of Medicine and Public Health, Section of Forensic Medicine, University of Verona, Policlinico G.B. Rossi, P.le L.A. Scuro, 37134 Verona, Italy. franco.tagliaro@univr.it
Bortolotti
Federica
F
Pascali
Jennifer P
JP
D019075:Electrophoresis, Capillary; D053593:Forensic Toxicology / Q000295:instrumentation / Q000379:methods*; D006801:Humans; D004364:Pharmaceutical Preparations / Q000032:analysis; D011506:Proteins / Q000032:analysis; D013237:Stereoisomerism; D014168:Transferrin / Q000031:analogs & derivatives / Q000032:analysis
D004364:Pharmaceutical Preparations; D011506:Proteins; D014168:Transferrin; C056759:carbohydrate-deficient transferrin