title: Rapid progression of mild to moderate aortic stenosis in patients older than 80 years.
abstract: OBJECTIVE
  The purpose of this study was to evaluate the rate of progression of mild and moderate aortic stenosis in patients aged 80 years and older.
  
  
  METHODS
  In all, 41 patients with mild and moderate aortic stenosis were included and divided into two groups by age: 19 patients aged 80 years and older (mean 84 +/- 4 years), and 21 patients younger than 80 years (mean 66 +/- 6 years).
  
  
  RESULTS
  The rate of degression of aortic valve area was more rapid in the 80 years and older age group than that in the younger than 80 years age group (-0.05 +/- 0.06 and -0.10 +/- 0.08 cm2/y, P = .014). Univariate and multivariate analysis of the rate of degression of aortic valve area were performed, and age was the only independent predictor of the rate of degression of aortic valve area.
  
  
  CONCLUSIONS
  Progression of mild and moderate aortic stenosis in patients aged 80 years and older was more rapid than that in those aged younger than 80 years.
authors.affiliation: Department of Cardiology, Kawasaki Medical School, Kurashiki, Japan. tteru@med.kawasaki-m.ac.jp <tteru@med.kawasaki-m.ac.jp>
authors.forename: Teruyoshi
authors.initials: T
authors.lastname: Kume
authors.forename: Takahiro
authors.initials: T
authors.lastname: Kawamoto
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Okura
authors.forename: Nozomi
authors.initials: N
authors.lastname: Watanabe
authors.forename: Eiji
authors.initials: E
authors.lastname: Toyota
authors.forename: Yoji
authors.initials: Y
authors.lastname: Neishi
authors.forename: Noriko
authors.initials: N
authors.lastname: Okahashi
authors.forename: Ryotaro
authors.initials: R
authors.lastname: Yamada
authors.forename: Kiyoshi
authors.initials: K
authors.lastname: Yoshida
mesh_terms: D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D000375:Aging; D001024:Aortic Valve Stenosis / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D018450:Disease Progression; D005260:Female; D006801:Humans; D008297:Male; D014463:Ultrasonography