title: Comparison of carotid Doppler ultrasound and computerised tomographic angiography in the evaluation of carotid artery stenosis.
abstract: OBJECTIVE
  To compare results of carotid Doppler ultrasound (CDUS) and spiral computerised tomographic angiography (CTA) in patients with suspected carotid artery stenosis and to evaluate their combined effect on decision making for carotid endarterectomy (CEA).
  
  
  METHODS
  A total of 107 patients were studied. All of the patients had CDUS followed by CTA as a standard method of investigation. Data included the indications for investigation, stenosis degree measured in both modalities, in addition to difficulties and limitations faced while doing them.
  
  
  RESULTS
  Out of the 214 carotid scans performed, 187 scans were included in the comparison, while 27 scans were excluded due to inadequate data or imaging difficulties. The overall concordance between both CDUS and CTA was 79.1% (148/187) (95% CI 0.72-0.83). CDUS under-estimated and over-estimated the degree of stenosis in 26/187 (14%, 95% CI 0.09-0.19) and 13/187 (7%, 95% CI 0.04-0.12), respectively. When CTA was considered in conjunction with CDUS, the decision regarding operative treatment was changed in 29/187 cases (16%) (95% CI 0.11-0.21).
  
  
  CONCLUSIONS
  CDUS remains the first line non-invasive imaging for carotid artery stenosis. However, in cases where it is inconclusive, CTA is an excellent, reliable, minimally invasive, and outpatient alternative for patient selection for CEA.
authors.affiliation: Vascular Department, Burnley General Hospital, East Lancashire Hospitals NHS Trust, UK.
authors.forename: M
authors.initials: M
authors.lastname: Titi
authors.forename: C
authors.initials: C
authors.lastname: George
authors.forename: D
authors.initials: D
authors.lastname: Bhattacharya
authors.forename: A
authors.initials: A
authors.lastname: Rahi
authors.forename: P M
authors.initials: PM
authors.lastname: Woodhead
authors.forename: W J
authors.initials: WJ
authors.lastname: Stevenson
authors.forename: A
authors.initials: A
authors.lastname: Pillai
authors.forename: H
authors.initials: H
authors.lastname: Al-Khaffaf
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000792:Angiography; D017536:Carotid Artery, Common / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D016893:Carotid Stenosis / Q000000981:diagnostic imaging* / Q000601:surgery; D003657:Decision Making; D016894:Endarterectomy, Carotid; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012107:Research Design; D012720:Severity of Illness Index; D036542:Tomography, Spiral Computed; D018615:Ultrasonography, Doppler, Color