Tc-99m ciprofloxacin imaging in acute cholecystitis.
OBJECTIVE
To evaluate the efficacy of a new nuclear imaging Infecton (Tc-99m ciprofloxacin) for the diagnosis of acute cholecystitis.


METHODS
Sixteen patients thought to have acute cholecystitis were included in this study. The diagnosis of acute cholecystitis was made based on clinical symptoms and ultrasonographic and pathologic findings.


RESULTS
The 16 patients were composed of 12 acute and 4 chronic cholecystitis patients. Twelve patients with acute cholecystitis were image-positive, including one false-positive. Four patients with chronic cholecystitis were image-negative, of whom three were true-negative. This nuclear imaging had a sensitivity of 91.7%, a specificity of 75%, a positive-predictive value of 91.7%, and a negative-predictive value of 75%.


CONCLUSIONS
Tc-99m ciprofloxacin imaging is easy to perform and applicable for the diagnosis of acute cholecystitis.
Choe
Yun-Mee
YM
Department of Surgery, Inha University Hospital, 7-206, 3 Ga Shinheung-dong, Jung-Gu, Incheon 400-711, South Korea.
Choe
Wonsick
W
Lee
Keon-Young
KY
Ahn
Seung-Ik
SI
Kim
Kwang
K
Cho
Young Up
YU
Choi
Sun Keun
SK
Hur
Yoon-Seok
YS
Kim
Sei-Joong
SJ
Hong
Kee-Chun
KC
Shin
Seok-Hwan
SH
Kim
Kyung-Rae
KR
Woo
Ze-Hong
ZH
D000208:Acute Disease; D000328:Adult; D000368:Aged; D002764:Cholecystitis / Q000000981:diagnostic imaging*; D002939:Ciprofloxacin / Q000031:analogs & derivatives*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015609:Organotechnetium Compounds; D011877:Radionuclide Imaging; D012680:Sensitivity and Specificity
D015609:Organotechnetium Compounds; C431804:Technetium Tc 99m ciprofloxacin; D002939:Ciprofloxacin