title: Synchronous male breast cancer and carcinoma of prostate in 90-year-old male, presented with spinal cord compression and multiple spine lytic lesions.
abstract: Male breast cancer and prostate cancer are similar in many ways, including the potential role of steroid hormones in their pathogenesis. We describe a 90-year-old male patient, who came with synchronous male breast cancer and carcinoma of the prostate. The first presentation was spinal cord compression with multiple lytic lesions in the thoracic and lumbar vertebrae on computed tomography. Serum tumor marker tests revealed an elevated serum PSA level of 104 ng/dL (normal <4 ng/dL) and a low free PSA of 11.6%. A histological examination of a specimen from a lytic lesion of the spine was consistent with metastatic breast cancer and a needle biopsy of the prostate showed adenocarcinoma, Gleason score 3 + 4.
authors.affiliation: Department of Oncology, Hadassah University Hospital, Jerusalem, Israel. talgrenader65@hotmail.com
authors.forename: Tal
authors.initials: T
authors.lastname: Grenader
authors.forename: Linda
authors.initials: L
authors.lastname: Shavit
mesh_terms: D000230:Adenocarcinoma / Q000097:blood / Q000188:drug therapy / Q000556:secondary*; D000369:Aged, 80 and over; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D018567:Breast Neoplasms, Male / Q000188:drug therapy / Q000473:pathology*; D017809:Fatal Outcome; D006801:Humans; D008297:Male; D009361:Neoplasm Invasiveness; D009378:Neoplasms, Multiple Primary; D010166:Palliative Care; D020335:Paraparesis / Q000209:etiology; D017430:Prostate-Specific Antigen / Q000097:blood; D011471:Prostatic Neoplasms / Q000097:blood / Q000188:drug therapy / Q000473:pathology*; D012983:Soft Tissue Neoplasms / Q000150:complications* / Q000473:pathology / Q000556:secondary*; D013115:Spinal Canal / Q000473:pathology; D013117:Spinal Cord Compression / Q000150:complications / Q000209:etiology*; D013125:Spinal Neoplasms / Q000532:radiotherapy / Q000556:secondary*
chemical_list: D017430:Prostate-Specific Antigen