Relationship of the serum procalcitonin level with the severity of acute pancreatitis.
The procalcitonin (PCT) level in the blood was determined in cases of acute pancreatitis. The PCT level was found to show a significant correlation with the severity of acute pancreatitis. Furthermore, the PCT level was significantly higher in the cases which developed MODS than in those which did not. The PCT level was significantly higher in the patients who eventually died than in those who survived. A significant correlation was observed between the serum PCT level and the serum tumor necrosis factor alpha level. Thus, PCT level was found to be a reliable indicator of the severity of acute pancreatitis.
Sato
Nobuhiro
N
Department of Critical Care Medicine, Iwate Medical University, 19-1 Uchimaru, Morioka 020- 8505, Japan.
Endo
Shigeatsu
S
Kasai
Takeshi
T
Inoue
Yoshihiro
Y
Fujino
Yasuhisa
Y
Onodera
Makoto
M
Imai
Satoko
S
Takahashi
Gaku
G
Miyata
Michiko
M
Kitamura
Michihiko
M
Wakabayashi
Go
G
D000208:Acute Disease; D000328:Adult; D015415:Biomarkers / Q000097:blood; D002116:Calcitonin / Q000097:blood*; D015740:Calcitonin Gene-Related Peptide; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009102:Multiple Organ Failure / Q000150:complications; D010195:Pancreatitis / Q000097:blood*; D011498:Protein Precursors / Q000097:blood*; D012720:Severity of Illness Index; D014409:Tumor Necrosis Factor-alpha / Q000097:blood
D015415:Biomarkers; C000606589:CALCA protein, human; D011498:Protein Precursors; D014409:Tumor Necrosis Factor-alpha; D002116:Calcitonin; D015740:Calcitonin Gene-Related Peptide