title: Feasibility of a reflexology and guided imagery intervention during chemotherapy: results of a quasi-experimental study.
abstract: OBJECTIVE
  To evaluate patient characteristics to predict selection and maintenance of a complementary therapy and the feasibility of a randomized clinical trial (RCT) of complementary therapies.
  
  
  METHODS
  Quasi-experimental, exploratory study, unblinded and nonrandomized.
  
  
  METHODS
  A comprehensive cancer center in Michigan.
  
  
  METHODS
  96 patients undergoing chemotherapy, predominantly Caucasian women.
  
  
  METHODS
  Consenting patients with caregivers could choose a reflexology, guided imagery, guided imagery plus reflexology, or interview-only group. Patients without caregivers were restricted to guided imagery or interview-only groups. Data on demographics, depression, anxiety, and functional status were collected using established instruments.
  
  
  METHODS
  Quality of life (QOL) and patient characteristics in relation to complementary therapy choice.
  
  
  RESULTS
  Patients who chose a complementary therapy rather than an interview only tended to be older and in worse health and had higher percentages of lung cancer, late-stage cancers, higher anxiety, depressive symptoms, and physical limitations at baseline. Patients lost from the guided imagery and guided imagery plus reflexology groups had greater symptom severity, depressive symptoms and anxiety, and worse physical and emotional well-being than those lost from the reflexology group.
  
  
  CONCLUSIONS
  Patient characteristics influence choice of complementary therapies, highlighting the need for RCTs to evaluate the true effect of complementary therapies on the QOL of patients with cancer. Further research on complementary therapies can help healthcare providers identify patients who are likely to benefit most by addressing nursing-sensitive outcomes.
  
  
  CONCLUSIONS
  An RCT of reflexology as a single therapy for females with breast cancer is most feasible compared to other complementary therapies.
authors.affiliation: The College of Nursing, Michigan State University, East Lansing, MI, USA. gwyatt@msu.edu
authors.forename: Gwen
authors.initials: G
authors.lastname: Wyatt
authors.forename: Alla
authors.initials: A
authors.lastname: Sikorskii
authors.forename: Azfar
authors.initials: A
authors.lastname: Siddiqi
authors.forename: Charles W
authors.initials: CW
authors.lastname: Given
mesh_terms: D000328:Adult; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D003131:Combined Modality Therapy / Q000379:methods; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D019018:Imagery, Psychotherapy; D007407:Interviews as Topic; D008297:Male; D008405:Massage; D009369:Neoplasms / Q000628:therapy*; D016896:Treatment Outcome
chemical_list: D000970:Antineoplastic Agents