Interactome of signaling networks in wheat: the protein-protein interaction between TaRAR1 and TaSGT1.
RAR1 and SGT1 are required for development and disease resistance in plants. In many cases, RAR1 and SGT1 regulate the resistance (R)-gene-mediated defense signaling pathways. Lr21 is the first identified NBS-LRR-type R protein in wheat and is required for resistance to the leaf rust pathogen. The Lr21-mediated signaling pathways require the wheat homologs of RAR1, SGT1, and HSP90. However, the molecular mechanisms of the Lr21-mediated signaling networks remain unknown. Here I present the DNA and protein sequences of TaRAR1 and TaSGT1, and demonstrate for the first time a direct protein-protein interaction between them.
Tai
Yin-Shan
YS
Cereal Crops Research Unit, U.S. Department of Agriculture-Agricultural Research Service, Fargo, ND 58105-5677, USA. yinshantai@gmail.com
D000595:Amino Acid Sequence; D002352:Carrier Proteins / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D017124:Conserved Sequence; D005964:Glucosyltransferases / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D008969:Molecular Sequence Data; D010940:Plant Proteins; D011485:Protein Binding; D016415:Sequence Alignment; D015398:Signal Transduction; D014908:Triticum / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*
D002352:Carrier Proteins; D010940:Plant Proteins; D005964:Glucosyltransferases