title: Characterization of a catalase-negative methicillin-resistant Staphylococcus aureus strain.
abstract: We describe an unusual clinical strain of catalase-negative methicillin-resistant Staphylococcus aureus sensu stricto. Sequence analysis of its catalase gene showed 99.60% identities to the catalase genes of the reference strains. A 5-base deletion, however, led to a shift of the nucleotide reading frame and a loss of the enzymatic activity.
authors.affiliation: Institute of Medical Microbiology, Johannes Gutenberg University, D-55101 Mainz, Germany.
authors.forename: B M
authors.initials: BM
authors.lastname: Grüner
authors.forename: S-R
authors.initials: SR
authors.lastname: Han
authors.forename: H-G
authors.initials: HG
authors.lastname: Meyer
authors.forename: U
authors.initials: U
authors.lastname: Wulf
authors.forename: S
authors.initials: S
authors.lastname: Bhakdi
authors.forename: E K
authors.initials: EK
authors.lastname: Siegel
mesh_terms: D000368:Aged; D002374:Catalase / Q000235:genetics* / Q000378:metabolism*; D004269:DNA, Bacterial / Q000737:chemistry / Q000235:genetics; D006801:Humans; D008297:Male; D016106:Methicillin Resistance; D008969:Molecular Sequence Data; D017422:Sequence Analysis, DNA; D013203:Staphylococcal Infections / Q000382:microbiology*; D013211:Staphylococcus aureus / Q000187:drug effects* / Q000201:enzymology* / Q000302:isolation & purification
chemical_list: D004269:DNA, Bacterial; D002374:Catalase