title: Interpretive criteria to differentiate low- and high-level mupirocin resistance in Staphylococcus aureus.
abstract: Meticillin-resistant Staphylococcus aureus isolates were classified into three mupirocin susceptibility groups by the disc diffusion method using 5 and 200 microg mupirocin discs. The zone diameter observed for a 5 microg disc distinguished Mup(S) from the resistant strains (either Mup(RL) or Mup(RH)). On the other hand, a 200 microg disc distinguished the high-resistance Mup(RH) strains from the other two (Mup(S) or Mup(RL)). Thus, the concomitant use of 5 and 200 microg mupirocin discs allowed the clear distinction among the three mupirocin susceptibility groups, Mup(S), Mup(RL) or Mup(RH).
authors.affiliation: Instituto de Microbiologia Prof. Paulo de Góes, Universidade Federal do Rio de Janeiro, RJ, Brazil.
authors.forename: Naira Elane
authors.initials: NE
authors.lastname: Moreira de Oliveira
authors.affiliation: Instituto de Microbiologia Prof. Paulo de Góes, Universidade Federal do Rio de Janeiro, RJ, Brazil.
authors.forename: Ana Paula Couto Marques
authors.initials: APCM
authors.lastname: Cardozo
authors.affiliation: Faculdade de Ciências Medicas, Universidade do Estado do Rio de Janeiro, RJ, Brazil.
authors.forename: Elizabeth de Andrade
authors.initials: EA
authors.lastname: Marques
authors.affiliation: Instituto de Microbiologia Prof. Paulo de Góes, Universidade Federal do Rio de Janeiro, RJ, Brazil.
authors.forename: Kátia Regina
authors.initials: KR
authors.lastname: Netto Dos Santos
authors.affiliation: Instituto de Microbiologia Prof. Paulo de Góes, Universidade Federal do Rio de Janeiro, RJ, Brazil.
authors.forename: Marcia Giambiagi
authors.initials: MG
authors.lastname: deMarval
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D024881:Drug Resistance, Bacterial; D006801:Humans; D016106:Methicillin Resistance; D008826:Microbial Sensitivity Tests / Q000379:methods / Q000592:standards*; D016712:Mupirocin / Q000494:pharmacology*; D013203:Staphylococcal Infections / Q000382:microbiology; D013211:Staphylococcus aureus / Q000187:drug effects*
chemical_list: D000900:Anti-Bacterial Agents; D016712:Mupirocin