Cytotype regulation by telomeric P elements in Drosophila melanogaster: interactions with P elements from M' strains.
P strains of Drosophila are distinguished from M strains by having P elements in their genomes and also by having the P cytotype, a maternally inherited condition that strongly represses P-element-induced hybrid dysgenesis. The P cytotype is associated with P elements inserted near the left telomere of the X chromosome. Repression by the telomeric P elements TP5 and TP6 is significantly enhanced when these elements are crossed into M' strains, which, like P strains, carry P elements, but have little or no ability to repress dysgenesis. The telomeric and M' P elements must coexist in females for this enhanced repression ability to develop. However, once established, it is transmitted maternally to the immediate offspring independently of the telomeric P elements themselves. Females that carry a telomeric P element but that do not carry M' P elements may also transmit an ability to repress dysgenesis to their offspring independently of the telomeric P element. Cytotype regulation therefore involves a maternally transmissible product of telomeric P elements that can interact synergistically with products from paternally inherited M' P elements. This synergism between TP and M' P elements also appears to persist for at least one generation after the TP has been removed from the genotype.
Simmons
Michael J
MJ
Department of Genetics, Cell Biology, and Development, 250 BioScience Center, University of Minnesota, 1445 Gortner Avenue, St. Paul, MN 55108-1095, USA. simmo004@umn.edu
Niemi
Jarad B
JB
Ryzek
Don-Felix
DF
Lamour
Cecile
C
Goodman
Joseph W
JW
Kraszkiewicz
Wojciech
W
Wolff
Ryan
R
D000818:Animals; D003433:Crosses, Genetic; D004251:DNA Transposable Elements; D004331:Drosophila melanogaster / Q000235:genetics*; D005260:Female; D017344:Genes, Insect; D050172:Genes, X-Linked; D006059:Gonadal Dysgenesis / Q000235:genetics; D008297:Male; D016615:Telomere / Q000235:genetics
D004251:DNA Transposable Elements