Variation in resistance to benzimidizole in different biocontrol agents based on protein sequence homology.
Benzimidazole resistance in thirty isolates of the biocontrol agents was studied with reference to specific mutations in the beta-tubulin genes. Our results suggest that apart from the correlation between specific mutations in the beta-tubulin gene and variation in resistance, the overall ratio of polar and non-polar amino-acids may also play a vital role in conferring benzimidazole resistance to these fungi.
Jarullah
B M S
BM
BRD School of Biosciences, Sardar Patel University, Vallabh Vidyanagar- 388120, Gujarat, India. bjarullah@yahoo.com
Subramanian
R B
RB
Jummanah
M J
MJ
D001203:Ascomycota / Q000187:drug effects / Q000235:genetics; D052982:Beauveria / Q000187:drug effects / Q000235:genetics; D001562:Benzimidazoles / Q000494:pharmacology*; D002219:Carbamates / Q000494:pharmacology; D025141:Drug Resistance, Fungal / Q000235:genetics; D010143:Paecilomyces / Q000187:drug effects / Q000235:genetics; D017386:Sequence Homology, Amino Acid; D014404:Tubulin / Q000235:genetics
D001562:Benzimidazoles; D002219:Carbamates; D014404:Tubulin; C031000:benzimidazole; C006698:carbendazim