[Gene doping: gene transfer and possible molecular detection].
The use of illegal substances in sports to enhance athletic performance during competition has caused international sports organizations such as the COI and WADA to take anti doping measures. A new doping method know as gene doping is defined as "the non-therapeutic use of genes, genetic elements and/or cells that have the capacity to enhance athletic performance". However, gene doping in sports is not easily identified and can cause serious consequences. Molecular biology techniques are needed in order to distinguish the difference between a "normal" and an "altered" genome. Further, we need to develop new analytic methods and biological molecular techniques in anti-doping laboratories, and design programs that avoid the non therapeutic use of genes.
Argüelles
Carlos Francisco
CF
Departamento de Farmacología del Deporte, Instituto Nacional de Rehabilitación, México, D.F., México. cfarguelles@prodygy.net.mx
Hernández-Zamora
Edgar
E
D004300:Doping in Sports / Q000379:methods*; D018014:Gene Transfer Techniques; D006801:Humans; D018482:Muscle, Skeletal / Q000254:growth & development