title: [3 + 2] Cycloaddition of acetylenes with azides to give 1,4-disubstituted 1,2,3-triazoles in a modular flow reactor.
abstract: The cycloaddition of acetylenes with azides to give the corresponding 1,4-disubstituted 1,2,3-triazoles is reported using immobilised reagents and scavengers in pre-packed glass tubes in a modular flow reactor.
authors.affiliation: Innovative Technology Centre (ACS), Department of Chemistry, Lensfield Road, Cambridge, CB2 1EW, UK.
authors.forename: Christopher D
authors.initials: CD
authors.lastname: Smith
authors.forename: Ian R
authors.initials: IR
authors.lastname: Baxendale
authors.forename: Steve
authors.initials: S
authors.lastname: Lanners
authors.forename: John J
authors.initials: JJ
authors.lastname: Hayward
authors.forename: Stephen C
authors.initials: SC
authors.lastname: Smith
authors.forename: Steven V
authors.initials: SV
authors.lastname: Ley
mesh_terms: D000480:Alkynes / Q000737:chemistry*; D001386:Azides / Q000737:chemistry*; D002384:Catalysis; D002626:Chemistry, Pharmaceutical / Q000295:instrumentation / Q000379:methods; D003300:Copper / Q000737:chemistry; D004867:Equipment Design; D009682:Magnetic Resonance Spectroscopy; D008956:Models, Chemical; D010455:Peptides / Q000737:chemistry; D014230:Triazoles / Q000737:chemistry*
chemical_list: D000480:Alkynes; D001386:Azides; D010455:Peptides; D014230:Triazoles; D003300:Copper