[Estimation of fatigue state in patient with CFS using actigraph and R-R interval power spectrum analysis].
OBJECTIVE
In this study, we try to estimate the fatigue state using actigraphy and R-R interval power spectrum analysis.


RESULTS
Actigraphy analysis showed that mean awake activity was decreased and duration of sleep was prolonged in patients with chronic fatigue syndrome (CFS), significantly (p < 0.001). Both of sleep episodes in wake period and wake episodes in sleep period were significantly increased in CFS patients in comparison with healthy volunteers (p < 0.001) In autonomic nerve analysis, sleep/awake ratio of high frequency component was significantly decreased in patients with CFS (p < 0.05).


CONCLUSIONS
The quality of sleep in patients with CFS was decreased because of increase of wake episodes in sleep period. Also the lack of parasympathetic activation during sleep period might be associated with the deterioration of sleep quality in patients with CFS.
Tajima
Seiki
S
Fatigue Clinical Center, Osaka City University Graduate School of Medicine.
Kuratsune
Hirohiko
H
Yamaguti
Kouzi
K
Takahashi
Ayumi
A
Takashima
Shoko
S
Watanabe
Yasuyoshi
Y
Nishizawa
Yoshiki
Y
D000328:Adult; D001341:Autonomic Nervous System / Q000503:physiopathology; D005221:Fatigue / Q000175:diagnosis* / Q000503:physiopathology; D015673:Fatigue Syndrome, Chronic / Q000175:diagnosis* / Q000503:physiopathology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D008991:Monitoring, Physiologic / Q000295:instrumentation / Q000379:methods*; D012890:Sleep / Q000502:physiology; D013057:Spectrum Analysis / Q000295:instrumentation / Q000379:methods*; D014851:Wakefulness / Q000502:physiology