title: [Detection of fungal metabolites showing toxic activity through Artemia salina bioassay].
abstract: The aim of this study was to detect toxic metabolites from fungi contaminating food and medicinal herbs by applying the toxicity assay to Artemia salina. According to toxicity percentages, the extracts were classified as nontoxic (NT), slightly toxic (ST), toxic (T) and highly toxic (HT). Those classified as T and HT were assayed for mycotoxins. Only 6 out of 71 strains were found to be T (8.5%) for A. salina. Penicillium brevicompactum Dierckx, isolated from sausages, was found to be HT, mainly due to the presence of ochratoxin A and two other unidentified metabolites.
authors.affiliation: Cátedra de Microbiología General, Facultad de Bioquímica y Ciencias Biológicas. Universidad Nacional del Litoral, Ciudad Universitaria, Paraje El Pozo, Santa Fe, Argentina. amgpodio@fbcb.unl.edu.ar
authors.forename: Ana María
authors.initials: AM
authors.lastname: González
authors.forename: Maximiliano
authors.initials: M
authors.lastname: Presa
authors.forename: María Gabriela
authors.initials: MG
authors.lastname: Latorre
authors.forename: María Cristina
authors.initials: MC
authors.lastname: Lurá
mesh_terms: D000818:Animals; D001156:Artemia / Q000187:drug effects*; D031175:Baccharis / Q000382:microbiology; D001681:Biological Assay / Q000379:methods*; D004340:Drug Contamination; D005504:Food Analysis / Q000379:methods; D005506:Food Contamination; D005516:Food Microbiology; D005658:Fungi / Q000302:isolation & purification* / Q000378:metabolism; D030019:Ilex paraguariensis / Q000382:microbiology; D032411:Lippia / Q000382:microbiology; D028501:Malva / Q000382:microbiology; D008461:Meat Products / Q000382:microbiology; D036142:Mentha piperita / Q000382:microbiology; D003904:Mitosporic Fungi / Q000302:isolation & purification / Q000378:metabolism; D009183:Mycotoxins / Q000032:analysis* / Q000494:pharmacology; D010946:Plants, Medicinal / Q000382:microbiology*; D013025:Glycine max / Q000382:microbiology; D014116:Toxicology / Q000379:methods*; D003313:Zea mays / Q000382:microbiology
chemical_list: D009183:Mycotoxins