Experimental design for regression analysis when the responses are subject to censoring.
Experimental design issues are investigated for regression models with possibly censored responses, arising typically from pharmacokinetic or virus dynamic experiments. Examples are provided for both locally and Bayesian optimal designs. A case study in pharmacokinetics is provided.
Han
Cong
C
TAP Pharmaceutical Products Inc., 675 North Field Drive, Lake Forest, IL 60045, United States. cong.han@tap.com
D000465:Algorithms; D016477:Artifacts; D003198:Computer Simulation; D008954:Models, Biological; D015233:Models, Statistical; D010599:Pharmacokinetics; D012044:Regression Analysis; D012107:Research Design