title: FGF: a web tool for Fishing Gene Family in a whole genome database.
abstract: Gene duplication is an important process in evolution. The availability of genome sequences of a number of organisms has made it possible to conduct comprehensive searches for duplicated genes enabling informative studies of their evolution. We have established the FGF (Fishing Gene Family) program to efficiently search for and identify gene families. The FGF output displays the results as visual phylogenetic trees including information on gene structure, chromosome position, duplication fate and selective pressure. It is particularly useful to identify pseudogenes and detect changes in gene structure. FGF is freely available on a web server at http://fgf.genomics.org.cn/
authors.affiliation: Beijing Institute of Genomics of Chinese Academy of Sciences, Beijing Genomics Institute, Beijing 101300, China.
authors.forename: Hongkun
authors.initials: H
authors.lastname: Zheng
authors.forename: Junjie
authors.initials: J
authors.lastname: Shi
authors.forename: Xiaodong
authors.initials: X
authors.lastname: Fang
authors.forename: Yuan
authors.initials: Y
authors.lastname: Li
authors.forename: Søren
authors.initials: S
authors.lastname: Vang
authors.forename: Wei
authors.initials: W
authors.lastname: Fan
authors.forename: Junyi
authors.initials: J
authors.lastname: Wang
authors.forename: Zhang
authors.initials: Z
authors.lastname: Zhang
authors.forename: Wen
authors.initials: W
authors.lastname: Wang
authors.forename: Karsten
authors.initials: K
authors.lastname: Kristiansen
authors.forename: Jun
authors.initials: J
authors.lastname: Wang
mesh_terms: D000465:Algorithms; D000818:Animals; D002874:Chromosome Mapping; D002875:Chromosomes / Q000648:ultrastructure; D019295:Computational Biology / Q000379:methods*; D019143:Evolution, Molecular; D020440:Gene Duplication; D016678:Genome; D006801:Humans; D016247:Information Storage and Retrieval; D020407:Internet; D008957:Models, Genetic; D010802:Phylogeny; D012984:Software; D014584:User-Computer Interface