title: Antiphospholipid syndrome: a predisposing factor for early onset HELLP syndrome.
abstract: Hemolysis elevated liver enzymes low platelets syndrome (HELLP) is a relatively rare pregnancy-related thrombotic microangiopathic disorder, usually observed during the third trimester. Its incidence seems to be increased in patients with antiphospholipid syndrome (APS). In this report, we describe a 33-year-old pregnant woman with previously known primary APS who developed early onset HELLP syndrome during the 15th week of gestation. We also review the literature about this interesting relationship between APS and HELLP.
authors.affiliation: 2nd Department of Internal Medicine, Propaudeutic, University of Athens, ATTIKON General University Hospital, Athens, Greece. tsiris1@otenet.gr
authors.forename: Panagiotis
authors.initials: P
authors.lastname: Tsirigotis
authors.forename: George
authors.initials: G
authors.lastname: Mantzios
authors.forename: Vassiliki
authors.initials: V
authors.lastname: Pappa
authors.forename: Konstantinos
authors.initials: K
authors.lastname: Girkas
authors.forename: George
authors.initials: G
authors.lastname: Salamalekis
authors.forename: Angellos
authors.initials: A
authors.lastname: Koutras
authors.forename: Vassiliki
authors.initials: V
authors.lastname: Giannopoulou
authors.forename: Konstantina
authors.initials: K
authors.lastname: Spirou
authors.forename: Alexia
authors.initials: A
authors.lastname: Balanika
authors.forename: Sotirios
authors.initials: S
authors.lastname: Papageorgiou
authors.forename: Anthi
authors.initials: A
authors.lastname: Travlou
authors.forename: John
authors.initials: J
authors.lastname: Dervenoulas
mesh_terms: D000028:Abortion, Induced; D000328:Adult; D016736:Antiphospholipid Syndrome / Q000150:complications*; D005260:Female; D020022:Genetic Predisposition to Disease; D005865:Gestational Age; D017359:HELLP Syndrome / Q000209:etiology*; D006801:Humans; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000209:etiology*; D011256:Pregnancy Outcome; D011262:Pregnancy Trimester, Second