title: Ghrelin is present in teeth.
abstract: Ghrelin belongs to the family of a gut-brain hormone that promotes food intake and controls energy balance. Recently, it has also been shown to regulate bone formation directly. Dental tissue shares several functional, developmental and anatomical similarities with bone, and in the present study we have investigated the presence of ghrelin in 44 human teeth using immunocytochemistry and radioimmunoassay. Both methods showed that the hormone is present in canines and molars, mainly in the odontoblasts but also in the pulp. Ghrelin could potentially play interesting physiological roles in teeth.
authors.affiliation: Department of Biochemistry and Clinical Biochemistry, Firat University, Medical School (Firat Medical Center), 23119 Elazig, Turkey. saydin1@hotmail.com
authors.forename: Suleyman
authors.initials: S
authors.lastname: Aydin
authors.forename: Ibrahim Hanefi
authors.initials: IH
authors.lastname: Ozercan
authors.forename: Hikmet
authors.initials: H
authors.lastname: Geckil
authors.forename: Ferda
authors.initials: F
authors.lastname: Dagli
authors.forename: Suna
authors.initials: S
authors.lastname: Aydin
authors.forename: Sinem
authors.initials: S
authors.lastname: Kumru
authors.forename: Nermin
authors.initials: N
authors.lastname: Kilic
authors.forename: Ibrahim
authors.initials: I
authors.lastname: Sahin
authors.forename: Mehmet Resat
authors.initials: MR
authors.lastname: Ozercan
mesh_terms: D003481:Cuspid / Q000737:chemistry; D054439:Ghrelin; D006801:Humans; D007150:Immunohistochemistry; D008963:Molar / Q000737:chemistry; D036361:Peptide Hormones / Q000032:analysis*; D011863:Radioimmunoassay; D014070:Tooth / Q000737:chemistry*
chemical_list: D054439:Ghrelin; D036361:Peptide Hormones