title: Modulation of neuronal interactions through neuronal synchronization.
abstract: Brain processing depends on the interactions between neuronal groups. Those interactions are governed by the pattern of anatomical connections and by yet unknown mechanisms that modulate the effective strength of a given connection. We found that the mutual influence among neuronal groups depends on the phase relation between rhythmic activities within the groups. Phase relations supporting interactions between the groups preceded those interactions by a few milliseconds, consistent with a mechanistic role. These effects were specific in time, frequency, and space, and we therefore propose that the pattern of synchronization flexibly determines the pattern of neuronal interactions.
authors.affiliation: F. C. Donders Centre for Cognitive Neuroimaging, Radboud University Nijmegen, 6525 EN Nijmegen, Netherlands. thilo.womelsdorf@fcdonders.ru.nl
authors.forename: Thilo
authors.initials: T
authors.lastname: Womelsdorf
authors.forename: Jan-Mathijs
authors.initials: JM
authors.lastname: Schoffelen
authors.forename: Robert
authors.initials: R
authors.lastname: Oostenveld
authors.forename: Wolf
authors.initials: W
authors.lastname: Singer
authors.forename: Robert
authors.initials: R
authors.lastname: Desimone
authors.forename: Andreas K
authors.initials: AK
authors.lastname: Engel
authors.forename: Pascal
authors.initials: P
authors.lastname: Fries
mesh_terms: D000200:Action Potentials; D000818:Animals; D002415:Cats; D004567:Electrodes, Implanted; D004594:Electrophysiology; D008254:Macaca nemestrina; D008297:Male; D009415:Nerve Net / Q000502:physiology; D009474:Neurons / Q000502:physiology*; D010296:Parietal Lobe / Q000033:anatomy & histology / Q000502:physiology*; D013702:Temporal Lobe / Q000033:anatomy & histology / Q000502:physiology*; D014795:Visual Pathways