[Advances of mesenchymal stem cells transplantation for treating intervertebral disc degeneration].
OBJECTIVE
To introduce the research of mesenchymal stem cells(MSCs) transplantation for treating intervertebral disc degeneration.


METHODS
The recent original articles about the MSCs transplantation for treating intervertebral disc degeneration were extensively reviewed.


RESULTS
Transplanted MSCs in intervertebral disc can express chrondcyte-like phenotype in certain conditions, increase matrix synthesis and release intervertebral disc degeneration.


CONCLUSIONS
MSCs transplantation for treating intervertebral disc degeneration may be a future approach.
Liang
Tao
T
Department of Orthopeadics, West China Hospital, Sichuan Universtiy, Chengdu Sichuan, 610041, P. R. China. LiangTao1234@sina.com
Liu
Hao
H
D018929:Cell Culture Techniques / Q000379:methods; D002454:Cell Differentiation; D002478:Cells, Cultured; D006801:Humans; D007403:Intervertebral Disc / Q000166:cytology / Q000473:pathology / Q000601:surgery*; D045164:Mesenchymal Stem Cell Transplantation / Q000379:methods; D059630:Mesenchymal Stem Cells / Q000166:cytology*; D012038:Regeneration / Q000502:physiology; D012189:Retrospective Studies; D013122:Spinal Diseases / Q000473:pathology / Q000601:surgery*; D023822:Tissue Engineering