title: [Dysfunctionnal uterin bleedings].
abstract: Dysfunctionnal uterine bleeding (DUB) is a significant health problem in premenopausal women. First line therapy is traditionally medical therapy but often ineffective. Hysterectomy is obviously effective in stopping bleeding but is associated with morbidity and is most costly. Endometrial ablation technique is becoming the first conservative line in the management of DUB. In 2007, the Cochrane Data Base, and the NICE published the new guidelines for DUB treatment. Pharmaceutical treatments should be considered in the following order: levonorgestrel-releasing intra uterine system and if hormonal treatment is not acceptable, tranexamic acid can be used. This is the exclusive line of treatment for women who desire to be pregnant, and the first step for the others one. The rapid development of second generation technique of endometrial destruction suggests that these techniques are becoming "the gold standart" for the patients without desire of future pregnancy. These techniques are easier that endometrial resection/ablation by hysteroscopy without major complications. In France, the National Health Insurance must find a codification CCAM for giving an exact price to the procedure. This new tarification could include the device cost and could avoid either inefficient procedure like datation and curetage or morbide procedure like hysterectomy.
authors.affiliation: Service de gynécologie-obstétrique et médecine de la reproduction, hôpital Antoine-Béclère, APHP, 157, rue de la Porte-de-Trivaux, 92140 Clamart cedex, France. herve.fernandez@abc.aphp.fr
authors.forename: H
authors.initials: H
authors.lastname: Fernandez
authors.forename: A
authors.initials: A
authors.lastname: Gervaise
mesh_terms: D004717:Endometrium / Q000601:surgery; D005260:Female; D006801:Humans; D015907:Hysteroscopy; D016912:Levonorgestrel / Q000008:administration & dosage; D011247:Pregnancy; D017697:Premenopause; D014148:Tranexamic Acid / Q000008:administration & dosage; D014592:Uterine Hemorrhage / Q000188:drug therapy / Q000601:surgery / Q000628:therapy*
chemical_list: D016912:Levonorgestrel; D014148:Tranexamic Acid