title: [A case of acute hepatitis a complicated by Guillain-Barré syndrome].
abstract: We report here a case of acute hepatitis A, which was complicated by Guillain-Barré syndrome (GBS). A 32-year old male admitted to our hospital with the symptoms of acute hepatitis and was diagnosed to have acute hepatitis A with positive IgM anti hepatitis A virus antibody. On 9th day after the onset of jaundice, acute progressive, ascending, symmetric motor paralysis were developed and eventually respiratory failure ensued. Cerebrospinal fluid analysis showed albumino-cytologic dissociation and nerve conduction velocity test suggested a polyradiculopathy. He was diagnosed to have GBS and treated with intravenous immunoglobulin and required a ventilatory support. After 90 hospital days, he recovered in ambulatory condition with the aid of crutches. The clinical course, prognosis and the outcome of neuropathic symptoms of GBS following acute hepatitis A were relatively poor in our case.
authors.affiliation: Department of Internal Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
authors.forename: Yun Jeong
authors.initials: YJ
authors.lastname: Bae
authors.forename: Kang Mo
authors.initials: KM
authors.lastname: Kim
authors.forename: Kwang Kuk
authors.initials: KK
authors.lastname: Kim
authors.forename: Jae Hyung
authors.initials: JH
authors.lastname: Rho
authors.forename: Hyun Ki
authors.initials: HK
authors.lastname: Lee
authors.forename: Yung Sang
authors.initials: YS
authors.lastname: Lee
authors.forename: Dong Jin
authors.initials: DJ
authors.lastname: Suh
mesh_terms: D000208:Acute Disease; D000328:Adult; D020275:Guillain-Barre Syndrome / Q000175:diagnosis* / Q000209:etiology / Q000628:therapy; D006506:Hepatitis A / Q000150:complications / Q000175:diagnosis*; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use; D008297:Male
chemical_list: D016756:Immunoglobulins, Intravenous