title: [Role of antibiotherapy in acute exacerbation of chronic obstructive pulmonary disease].
abstract: Two thirds of the exacerbations of chronic obstructive pulmonary disease (COPD) are caused by infections of the respiratory tract. The causative microorganisms differ according to the degree of COPD severity, previous antibiotic therapy and prior bacterial infections. Antibiotics and intensification of bronchodilator therapy are the cornerstones of the management of moderate and severe exacerbations of COPD. Prompt therapy of COPD exacerbations has been shown to reduce the likelihood of hospitalisation and improve the quality of life. In this article, we have reviewed current recommendations regarding the use of antibiotics in the treatment of COPD exacerbations.
authors.affiliation: Service des maladies infectieuses, Département de médecine, CHUV, 101I Lausanne. matthias.cavassini@chuv.ch
authors.forename: M
authors.initials: M
authors.lastname: Cavassini
authors.forename: T
authors.initials: T
authors.lastname: Calandra
authors.forename: P O
authors.initials: PO
authors.lastname: Bridevaux
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D006801:Humans; D029424:Pulmonary Disease, Chronic Obstructive / Q000188:drug therapy* / Q000209:etiology; D012141:Respiratory Tract Infections / Q000150:complications* / Q000188:drug therapy*
chemical_list: D000900:Anti-Bacterial Agents