Pheohyphomycotic soft tissue disease caused by Alternaria alternata in a kidney transplant patient: a case report and literature review.
A 61-year-old Italian man, who underwent a renal transplantation 8 years ago, receiving azathioprine, prednisone, and cyclosporine for immunosuppressive therapy, presented with a large reddish indurated plaque with a central ulcer, which was slowly enlarged, on the right knee. From the diseased tissue biopsy, a dematiaceous fungus matching Alternaria alternata in all essential characters was isolated in pure culture. This is an uncommon fungal complication in a kidney transplant patient. A detailed morphological description of the isolate is provided as well as review of the literature.
Farina
C
C
Microbiology Institute, Azienda Ospedaliera Ospedali Riuniti di Bergamo, Bergamo, Italy. Farina.Claudio@sancarlo.mi.it
Gotti
E
E
Parma
A
A
Naldi
L
L
Goglio
A
A
D000328:Adult; D000368:Aged; D000528:Alternaria; D005260:Female; D006801:Humans; D016030:Kidney Transplantation / Q000009:adverse effects* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009181:Mycoses / Q000209:etiology* / Q000473:pathology; D011183:Postoperative Complications / Q000382:microbiology / Q000473:pathology