title: Three cases of cytomegalovirus infection following pancreatic islet transplantation.
abstract: Transmission of cytomegalovirus (CMV) is uncommon in patients transplanted with CMV-mismatched pancreatic islets, and CMV-seropositive recipients rarely experience reactivation of the virus or reinfection from a CMV-positive graft. This study describes three cases of CMV infection following islet transplantation for type 1 diabetes despite prophylaxis with valganciclovir. Further studies are needed to evaluate risk factors for CMV transmission and reactivation in this patient population.
authors.affiliation: Division of Endocrinology, University of British Columbia, Vancouver, Canada.
authors.forename: N
authors.initials: N
authors.lastname: Yakubovich
authors.forename: M A
authors.initials: MA
authors.lastname: Fung
authors.forename: D M
authors.initials: DM
authors.lastname: Thompson
mesh_terms: D000998:Antiviral Agents / Q000627:therapeutic use; D003586:Cytomegalovirus Infections / Q000175:diagnosis* / Q000188:drug therapy / Q000517:prevention & control / Q000635:transmission; D015774:Ganciclovir / Q000627:therapeutic use; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use; D016381:Islets of Langerhans Transplantation / Q000009:adverse effects*; D012008:Recurrence
chemical_list: D000998:Antiviral Agents; D016756:Immunoglobulins, Intravenous; D015774:Ganciclovir