title: Hand eczema is common and multifactorial.
abstract: Clinicians agree that hand eczema is multifactorial, although there are many uncertainties regarding causative factors. Atopic dermatitis is assumed to be a major risk factor, whereas the role of allergies is overestimated. Twin studies may shed light on the contribution of other endogenous, possibly genetic factors versus the role of exposure to environmental agents, with the latter being amenable to prevention and intervention.
authors.affiliation: Dermatology Department, University Medical Centre Groningen, University of Groningen, Groningen, The Netherlands. p.j.coenraads@med.umcg.nl
authors.forename: Pieter-Jan
authors.initials: PJ
authors.lastname: Coenraads
mesh_terms: D003876:Dermatitis, Atopic / Q000150:complications; D004485:Eczema / Q000453:epidemiology* / Q000209:etiology* / Q000235:genetics; D004781:Environmental Exposure / Q000009:adverse effects / Q000517:prevention & control; D020022:Genetic Predisposition to Disease; D006225:Hand / Q000473:pathology*; D006306:Health Surveys; D006801:Humans; D006967:Hypersensitivity / Q000150:complications; D015994:Incidence; D011788:Quality of Life; D012307:Risk Factors; D018433:Twin Studies as Topic