title: Comparative assessment of ECG dynamics in myocardial infarction according to reperfusion therapy approach (primary and facilitated coronary angioplasty) and timing of the procedure.
abstract: OBJECTIVE
  The aim of this study was to compare electrocardiogram (ECG)-12 dynamics depending on the methods of facilitated and primary angioplasty in patients with acute coronary syndrome. The ECG changes in 81 patients - 73 patients with acute myocardial infarction and 8 patients with unstable angina pectoris - were studied.
  
  
  METHODS
  The ECG analysis before reperfusion therapy and after angioplasty included: dynamics of summary elevation (Sigma ST+) and depression (Sigma ST-) of ST segment and changes of summary value of R waves (Sigma R) in 12 leads. The results were estimated with consideration for the length of the period from the beginning of pain syndrome till treatment and topics of the infraction-related artery.
  
  
  RESULTS
  According to our data, there was no difference between facilitated and primary transluminal coronary angioplasty in their effect on focal myocardial variation dynamics and the size of peri-infarction zone.
  
  
  CONCLUSIONS
  A reliable decrease in elevation and depression of ST segment was observed in reperfusion therapy not later than 6 hours after the beginning of pain syndrome. When reperfusion therapy is begun later, dynamics of summary values of ST segment elevation and depression before and after treatment are not reliable.
authors.affiliation: Russian Cardiology Research Center, Moscow, Russia. anrogoza@cardio.ru
authors.forename: G V
authors.initials: GV
authors.lastname: Ryabykina
authors.forename: A V
authors.initials: AV
authors.lastname: Sozykin
authors.forename: S V
authors.initials: SV
authors.lastname: Dobrovolskaya
mesh_terms: D000368:Aged; D015906:Angioplasty, Balloon, Coronary / Q000706:statistics & numerical data*; D004562:Electrocardiography; D006801:Humans; D008875:Middle Aged; D009203:Myocardial Infarction / Q000453:epidemiology / Q000503:physiopathology / Q000628:therapy*; D017063:Outcome Assessment, Health Care; D012426:Russia / Q000453:epidemiology; D015912:Thrombolytic Therapy / Q000706:statistics & numerical data*; D013997:Time Factors