Back to basics: Sox genes.
Sox genes are indispensable for multiple aspects of development. This primer briefly describes shared properties of the Sox gene family, and five well-characterized examples of vertebrate developmental mechanisms governed by Sox gene subgroups: testis development, central nervous system neurogenesis, oligodendrocyte development, chondrogenesis, and neural crest cell development. Also featured is an interview about current issues in the field with experts Jonas Muhr, Ph.D. and Robert Kelsh, Ph.D.
Kiefer
Julie C
JC
Department of Neurobiology and Anatomy, University of Utah, Salt Lake City, Utah 84132, USA. jkiefer@neuro.utah.edu
D000818:Animals; D002454:Cell Differentiation / Q000235:genetics; D004268:DNA-Binding Proteins / Q000235:genetics; D047108:Embryonic Development / Q000235:genetics; D006609:High Mobility Group Proteins / Q000235:genetics*; D008297:Male; D051379:Mice; D055748:SOXB1 Transcription Factors; D051876:Sex-Determining Region Y Protein / Q000235:genetics
D004268:DNA-Binding Proteins; D006609:High Mobility Group Proteins; D055748:SOXB1 Transcription Factors; D051876:Sex-Determining Region Y Protein; C098693:Sox1 protein, mouse