title: Comparison between genes of Alzheimer's disease and brain tissue of others.
abstract: We have examined samples from 14 donors that were prepared from 44 different anatomical regions of the brain. These samples were prepared both as frozen formalin-fixed, paraffin embedded. There were 310 frozen samples and 367 fixed samples. A total of 265 of the frozen samples were tested for RNA quality. A very high quality was obtained with 122 of these frozen samples (44%). The sample numbers were not large enough to draw conclusions about RNA quality for individual brain regions. Silver staining was performed on some samples and 5 of 7 samples tested from one donor diagnosed with Alzheimer's like dementia showed evidence of Alzheimer's disease by this method.
authors.affiliation: National Institute of Neurology and Psychiatry, Budapest, Hungary.
authors.forename: Péter
authors.initials: P
authors.lastname: Gaszner
authors.forename: László
authors.initials: L
authors.lastname: Havas
mesh_terms: D000544:Alzheimer Disease / Q000473:pathology*; D001344:Autopsy; D001923:Brain Chemistry; D002544:Cerebral Infarction / Q000150:complications / Q000473:pathology; D003704:Dementia / Q000209:etiology / Q000473:pathology; D005629:Frozen Sections; D006801:Humans; D012313:RNA / Q000032:analysis*; D012563:Schizophrenia, Paranoid / Q000150:complications / Q000473:pathology
chemical_list: D012313:RNA