Endoscopy-related infections and toxic reactions: an international comparison.
This article is an analysis of the characteristics of exogenous endoscopy-related infections, pseudoinfections, and toxic reactions that have occurred worldwide during the period 1974 - 2004. A systematic review of the scientific literature published between 1966 and 2004 was conducted in Medline and the Food and Drug Administration Reports database, using a prospective protocol developed by the authors. The literature review identified 140 outbreaks, reported in 134 scientific articles. More than 94 % of the outbreaks identified could have been prevented by improved decontamination processes. Proper decontamination practices and the improvement of surveillance systems could reduce the clinical burden associated with exogenous endoscopy-related events.
Seoane-Vazquez
E
E
College of Pharmacy, The Ohio State University, Columbus, Ohio 43210, USA. pharmacoeconomics@osu.edu
Rodriguez-Monguio
R
R
Visaria
J
J
Carlson
A
A
D001424:Bacterial Infections / Q000453:epidemiology* / Q000209:etiology*; D003428:Cross Infection / Q000453:epidemiology* / Q000382:microbiology; D004196:Disease Outbreaks; D004203:Disinfection / Q000379:methods; D004724:Endoscopy / Q000009:adverse effects* / Q000379:methods; D004866:Equipment Contamination / Q000706:statistics & numerical data*; D005260:Female; D006801:Humans; D015994:Incidence; D017053:Infection Control / Q000379:methods; D007391:International Cooperation; D008297:Male; D014481:United States / Q000453:epidemiology