A translational approach to studying preterm labour.
Preterm labour continues to be a major contributor to neonatal and infant morbidity. Recent data from the USA indicate that the number of preterm deliveries (including those associated with preterm labour) has risen in the last 20 years by 30%. This increase is despite considerable efforts to introduce new therapies for the prevention and treatment of preterm labour and highlights the need to assess research in this area from a fresh perspective. In this paper we discuss i) the limitations of our knowledge concerning prediction, prevention and treatment of preterm labour and ii) future multidisciplinary strategies for improving our approach.
Tribe
Rachel Marie
RM
Maternal and Fetal Research Unit, Division of Reproduction and Endocrinology, King's College London, St, Thomas' Hospital Campus, London, UK. rachel.tribe@kcl.ac.uk
D016207:Cytokines / Q000378:metabolism; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000517:prevention & control; D007378:Interleukins / Q000378:metabolism; D008429:Maternal Welfare; D008967:Molecular Biology / Q000379:methods; D007752:Obstetric Labor, Premature / Q000276:immunology / Q000517:prevention & control*; D011247:Pregnancy; D015149:Tocolytic Agents / Q000627:therapeutic use
D016207:Cytokines; D007378:Interleukins; D015149:Tocolytic Agents