title: Double resistance to imatinib and AMG 706 caused by multiple acquired KIT exon 17 mutations in a gastrointestinal stromal tumour.
authors.forename: Florian
authors.initials: F
authors.lastname: Grabellus
authors.forename: Peter
authors.initials: P
authors.lastname: Ebeling
authors.forename: Karl
authors.initials: K
authors.lastname: Worm
authors.forename: Sien-Yi
authors.initials: SY
authors.lastname: Sheu
authors.forename: Gerald
authors.initials: G
authors.lastname: Antoch
authors.forename: Andrea
authors.initials: A
authors.lastname: Frilling
authors.forename: Kurt W
authors.initials: KW
authors.lastname: Schmid
mesh_terms: D001483:Base Sequence; D001549:Benzamides; D018432:Drug Resistance, Multiple / Q000235:genetics; D019008:Drug Resistance, Neoplasm / Q000235:genetics; D005260:Female; D046152:Gastrointestinal Stromal Tumors / Q000188:drug therapy*; D006801:Humans; D000068877:Imatinib Mesylate; D007211:Indoles / Q000627:therapeutic use*; D008875:Middle Aged; D009536:Niacinamide / Q000031:analogs & derivatives* / Q000627:therapeutic use; D009841:Oligonucleotides; D010879:Piperazines / Q000627:therapeutic use*; D017354:Point Mutation; D019009:Proto-Oncogene Proteins c-kit / Q000235:genetics*; D011743:Pyrimidines / Q000627:therapeutic use*
chemical_list: D001549:Benzamides; D007211:Indoles; D009841:Oligonucleotides; D010879:Piperazines; D011743:Pyrimidines; D009536:Niacinamide; D000068877:Imatinib Mesylate; D019009:Proto-Oncogene Proteins c-kit; C519562:imetelstat