Hepatocellular carcinoma with direct invasion to the stomach.
A 71-year-old man was admitted to our hospital with abdominal pain. Hepatocellular carcinoma (HCC) had been diagnosed 2 years earlier and he had undergone 7 courses of intra-hepato-arterial chemotherapy (IHAC). We performed gastrointestinal fiberscopy and identified a massive protrusion on the lesser curvature. Abdominal contrast-enhanced computed tomography revealed multiple hepatic masses and an extrahepatic enlarged mass with invasion to the pancreas and stomach. A specimen for endoscopic biopsy revealed adenocarcinoma that stained positive for alpha-fetoprotein. Gastrointestinal bleeding resulting from direct invasion of HCC is unusual.
Inoue
Hiromu
H
Division of Gastroenterology and Department of Integrated Medicine I, Omiya Medical Center, Jichi Medical School, Saitama. hiromuinoue-gi@umin.ac.jp
Sawada
Yukihisa
Y
Ochiai
Kaori
K
Honda
Hideaki
H
Murayama
Junko
J
Kudo
Yasutaka
Y
Nakashima
Yoshiyuki
Y
Sagihara
Noriyoshi
N
Miyatani
Hiroyuki
H
Nakamura
Ikuo
I
Yoshida
Yukio
Y
D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage; D006528:Carcinoma, Hepatocellular / Q000473:pathology* / Q000628:therapy; D006801:Humans; D007261:Infusions, Intra-Arterial; D008113:Liver Neoplasms / Q000473:pathology* / Q000628:therapy; D008297:Male; D009361:Neoplasm Invasiveness; D011859:Radiography; D013274:Stomach Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000628:therapy; D016896:Treatment Outcome