Bromination of deactivated aromatics: a simple and efficient method.
Highly deactivated aromatic compounds were smoothly monobrominated by treatment with N-bromosuccinimide (NBS) in concentrated H2SO4 medium affording the corresponding bromo derivatives in good yields. Mild reaction conditions and simple workup provides a practical and commercially viable route for the synthesis of bromo compounds of deactivated aromatics.
Rajesh
K
K
Shasun Research Centre, No. 27 Vandaloor-Kelambakkam Road, Keelakottaiyur, Chennai-600 048, India.
Somasundaram
M
M
Saiganesh
R
R
Balasubramanian
K K
KK
D001966:Bromine / Q000737:chemistry*; D009930:Organic Chemicals / Q000737:chemistry*
D009930:Organic Chemicals; D001966:Bromine