title: [Advances of mesenchymal stem cells transplantation for treating intervertebral disc degeneration].
abstract: OBJECTIVE
  To introduce the research of mesenchymal stem cells(MSCs) transplantation for treating intervertebral disc degeneration.
  
  
  METHODS
  The recent original articles about the MSCs transplantation for treating intervertebral disc degeneration were extensively reviewed.
  
  
  RESULTS
  Transplanted MSCs in intervertebral disc can express chrondcyte-like phenotype in certain conditions, increase matrix synthesis and release intervertebral disc degeneration.
  
  
  CONCLUSIONS
  MSCs transplantation for treating intervertebral disc degeneration may be a future approach.
authors.affiliation: Department of Orthopeadics, West China Hospital, Sichuan Universtiy, Chengdu Sichuan, 610041, P. R. China. LiangTao1234@sina.com
authors.forename: Tao
authors.initials: T
authors.lastname: Liang
authors.forename: Hao
authors.initials: H
authors.lastname: Liu
mesh_terms: D018929:Cell Culture Techniques / Q000379:methods; D002454:Cell Differentiation; D002478:Cells, Cultured; D006801:Humans; D007403:Intervertebral Disc / Q000166:cytology / Q000473:pathology / Q000601:surgery*; D045164:Mesenchymal Stem Cell Transplantation / Q000379:methods; D059630:Mesenchymal Stem Cells / Q000166:cytology*; D012038:Regeneration / Q000502:physiology; D012189:Retrospective Studies; D013122:Spinal Diseases / Q000473:pathology / Q000601:surgery*; D023822:Tissue Engineering