Treatment of cyclophosphamide-induced intractable hemorrhagic cystitis.
We report the successful use of prostaglandin F2 alpha continous bladder irrigation in two patients for the treatment of intractable cyclophosphamide-induced hemorrhagic cystitis which was resistant to conventional therapy in two patients. A 0.7 mg% solution of prostaglandin F2 alpha was used for continuous bladder irrigation at a rate of 150 to 200 cc/hr for four days. The response was complete in both patients and no side effects were noted.
Bazarbashi
M S
MS
Department of Oncology, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia, and Division of Hematology, Henry Ford Hospital, Detroit, and Division of Hematology/Oncology, Wayne State University, Detroit, Michigan, USA.
Shurafa
M S
MS
Karanes
C
C