title: Radiotherapy for Erdheim-Chester disease.
abstract: A 42-year-old woman suffered from pain in both legs, and fever. She was diagnosed with Erdheim-Chester disease (ECD), based upon bone biopsy. Initially, she received steroid therapy, which led to temporary improvement. However, bone pain in the right femur was so progressive that, as a trial course of radiation therapy, she was given a total dose of 18 Gy in ten fractions to the right distal femur. She showed a gradual response, and the local pain became controllable. Erdheim-Chester disease (ECD) is an uncommon, non-Langerhans form of histiocytosis, which is characterized by radiological and pathological findings, but its treatment is still controversial. We here present a representative case report of radiotherapy for ECD.
authors.affiliation: Department of Radiology, Maizuru Municipal Hospital, Kyoto, Japan. k-matsui@hospital.toyooka.hyogo.jp
authors.forename: Katsunori
authors.initials: K
authors.lastname: Matsui
authors.forename: Yasushi
authors.initials: Y
authors.lastname: Nagata
authors.forename: Masahiro
authors.initials: M
authors.lastname: Hiraoka
mesh_terms: D000328:Adult; D019583:Dose Fractionation, Radiation; D031249:Erdheim-Chester Disease / Q000150:complications / Q000473:pathology / Q000532:radiotherapy*; D005260:Female; D006801:Humans; D010148:Intractable Pain / Q000209:etiology / Q000532:radiotherapy*