Sarcoid myositis with muscle weakness as a presenting symptom.
A 54-year-old woman complaining of muscle weakness and weight loss was admitted to our hospital with suspected polymyositis. Muscle biopsy revealed Langhans-type giant cells and noncaseating granulomas. Therefore, sarcoid myositis was diagnosed. The patient was treated with prednisolone, and the symptoms improved gradually. Generally, sarcoidosis is identified clinically in patients with foggy vision or mediastinal lymphadenopathy, but muscular weakness may be an infrequently observed initial symptom. Sarcoidosis should be considered in the differential diagnosis of polymyositis.
Yamada
Hideyasu
H
Clinical Immunology, Advanced Biomedical Applications, Graduate School of Comprehensive Human Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8575, Japan.
Ishii
Wataru
W
Ito
Satoshi
S
Iwanami
Keiichi
K
Ogishima
Hiroshi
H
Suzuki
Takeshi
T
Mamura
Mizuko
M
Goto
Daisuke
D
Matsumoto
Isao
I
Tsutsumi
Akito
A
Sumida
Takayuki
T
D000893:Anti-Inflammatory Agents; D005260:Female; D006801:Humans; D008875:Middle Aged; D018908:Muscle Weakness / Q000209:etiology*; D017285:Polymyositis / Q000188:drug therapy / Q000209:etiology*; D011239:Prednisolone / Q000627:therapeutic use; D012507:Sarcoidosis / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy
D000893:Anti-Inflammatory Agents; D011239:Prednisolone