title: Pregabalin: new indication. Generalised anxiety: better to use benzodiazepine.
abstract: Seven placebo-controlled trials have shown that pregabalin has a modest effect on generalised anxiety in the short term. Pregabalin has not been shown to be as effective as a benzodiazepine or better tolerated.
mesh_terms: D000328:Adult; D014151:Anti-Anxiety Agents / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D000927:Anticonvulsants / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D001007:Anxiety / Q000188:drug therapy*; D001569:Benzodiazepines / Q000627:therapeutic use; D002986:Clinical Trials as Topic; D017277:Drug Approval; D005260:Female; D005602:France; D006801:Humans; D008297:Male; D010698:Phobic Disorders / Q000188:drug therapy; D010919:Placebos; D016896:Treatment Outcome; D005680:gamma-Aminobutyric Acid / Q000008:administration & dosage / Q000009:adverse effects / Q000031:analogs & derivatives / Q000627:therapeutic use*
chemical_list: D014151:Anti-Anxiety Agents; D000927:Anticonvulsants; D010919:Placebos; D001569:Benzodiazepines; D005680:gamma-Aminobutyric Acid