title: Dammarane-type glycosides from Gynostemma pubescens.
abstract: Triterpene saponins 1-8 were isolated from the aerial parts of Gynostemma pubescens. Among them, compounds 1-4, 8 possess carboxylic groups at both C-21 and C-29, 5 contains a carboxylic group at C-21 and an aldehyde function at C-29, whereas 6 and 7 contain carboxylic groups at C-21 and hydroxymethylene groups at C-29. Their structural elucidation was accomplished by extensive spectroscopic methods including application of 1D (1H, (13)C, (13)C DEPT) and 2D NMR experiments (HMQC, HMBC, HSQC), HRESIMS analysis, as well as by chemical degradation.
authors.affiliation: Shanghai Research Center for Modernization of Traditional Chinese Medicine, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 199 Guoshoujing Road, Shanghai 201203, PR China.
authors.forename: Zhengyi
authors.initials: Z
authors.lastname: Yang
authors.forename: Qiuqun
authors.initials: Q
authors.lastname: Chen
authors.forename: Lihong
authors.initials: L
authors.lastname: Hu
mesh_terms: D029774:Gynostemma / Q000737:chemistry*; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D010936:Plant Extracts / Q000737:chemistry; D012503:Saponins / Q000737:chemistry* / Q000302:isolation & purification; D014315:Triterpenes / Q000737:chemistry* / Q000302:isolation & purification
chemical_list: D010936:Plant Extracts; D012503:Saponins; D014315:Triterpenes