Morbidity due to Schistosoma mansoni--Entamoeba histolytica coinfection in hamsters (Mesocricetus auratus).
Data on Schistosoma mansoni-Entamoeba histolytica coinfection are scarce in the literature. In the present study, hamsters that had been infected for 70 days with Schistosoma mansoni (LE strain) were inoculated via the portal vein with two strains of trophozoites of Entamoeba histolytica: ICB-EGG (highly virulent) and ICB-RPS (non-virulent). The most evident result of coinfection was increased morbidity and mortality, in comparison with either of the infections alone. Histologically, there were no evident signs of interaction between these two infections. The morphological findings of schistosomal granuloma and amoebic abscesses in the liver were similar to those seen in the respective single-infection controls. However, there was severe wasting of the animals with both infections and greater numbers of amoebic lesions in their livers. The results obtained indicated that schistosomiasis aggravates the course of amoebiasis in hamsters.
Dolabella
Silvio Santana
SS
Laboratório de Amebíase, Departamento de Parasitologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, MG.
Coelho
Paulo Marcos Zech
PM
Borçari
Izabela Torquetti
IT
Mello
Nelson Azevedo Santos Teixeira
NA
Andrade
Zilton de Araújo
Zde A
Silva
Edward Felix
EF
D000818:Animals; D006224:Cricetinae; D004748:Entamoeba histolytica / Q000472:pathogenicity*; D005260:Female; D008101:Liver Abscess, Amebic / Q000150:complications* / Q000401:mortality / Q000473:pathology; D008297:Male; D008647:Mesocricetus; D012550:Schistosoma mansoni / Q000472:pathogenicity*; D012555:Schistosomiasis mansoni / Q000150:complications* / Q000401:mortality / Q000473:pathology; D012720:Severity of Illness Index