Familial ankyloglossia (tongue-tie).
Ankyloglossia (tongue-tie) is a congenital anomaly with a prevalence of 4-5% and characterized by an abnormally short lingual frenulum. For unknown reasons the abnormality seems to be more common in males. The pathogenesis of ankyloglossia is not known. The author reports a family with isolated ankyloglossia inherited as an autosomal dominant trait. The identification of the defective gene(s) causing ankyloglossia might reveal novel information on the craniofacial embryogenesis and its disorders.
Klockars
Tuomas
T
Department of Otorhinolaryngology, Kymenlaakso Central Hospital, Kotkantie 41, 48210 Kotka, Finland. tuomas.klockars@fimnet.fi
D006801:Humans; D008035:Lingual Frenum / Q000002:abnormalities* / Q000601:surgery*; D010375:Pedigree; D014060:Tongue Diseases / Q000235:genetics*