[Determination of the content of water in dry preparations of the vaccine strain Francisella tularensis by NMR-relaxation technique].
Frozen-dried preparations were studied for the impact of moisture content of the nuclear magnetic resonance parameter that was a ratio of the amplitudes of a slow component and a rapid one of a free induction signal from the protons of samples. It was found that there was a linear correlation between this parameter and the moisture content of biological materials, by using bovine serum albumin (BSA) as examples, with lactose and biomass of Francisella tularensis. Formulas were derived for calculating the moisture content of the test preparations.
Fediukina
G N
GN
Volkov
V Ia
VIa
D000818:Animals; D001428:Bacterial Vaccines / Q000737:chemistry*; D018533:Biomass; D002417:Cattle; D005604:Francisella tularensis; D007785:Lactose / Q000032:analysis; D009682:Magnetic Resonance Spectroscopy; D012710:Serum Albumin, Bovine / Q000032:analysis; D014867:Water / Q000032:analysis*
D001428:Bacterial Vaccines; D014867:Water; D012710:Serum Albumin, Bovine; D007785:Lactose