Comparison of the effects on cardiopulmonary function of ultrathin transnasal versus normal diameter transoral esophagogastroduodenoscopy in Japan.
OBJECTIVE
Transnasal esophagogastroduodenoscopy (EGD) is reported to be more pleasant than conventional transoral EGD. In this study, we compared the hemodynamic effects of transnasal and transoral EGD.


METHODS
The subjects were 120 patients with upper gastrointestinal conditions. Transnasal and transoral EGD were performed on 60 subjects each. Oxygen saturation, heart rate and blood pressure were monitored. Subjects were also asked for their condition with each EGD.


RESULTS
VAS scores for discomfort at the insertion, and for trouble breathing and nausea during the procedure, were significantly lower for transnasal than for transoral EGD. A significant increase in the heart rate and significant decrease in oxygen saturation were seen only in the transoral group during EGD. The double product (heart rate x systolic blood pressure) was also significantly increased only in the transoral group. No significant changes were seen in the transnasal EGD.


CONCLUSIONS
Double product has been reported to correlate with myocardial oxygen consumption. Transnasal EGD is a safe technique, and is not only less stressful to patients, but also has fewer hemodynamic effects than the transoral method.
Kawai
Takashi
T
Endoscopy Center, Tokyo Medical University Hospital, 6-7-1 Nishi-Shinjuku, Shinjuku-ku, Tokyo 160-0023, Japan. t-kawai@tokyo-med.ac.jp
Miyazaki
Ikuko
I
Yagi
Kenji
K
Kataoka
Mikinori
M
Kawakami
Kohei
K
Yamagishi
Tetsuya
T
Sofuni
Atsushi
A
Itoi
Takao
T
Moriyasu
Fuminori
F
Osaka
Yoshiaki
Y
Takagi
Yuu
Y
Aoki
Tatsuya
T
D000368:Aged; D001794:Blood Pressure; D016145:Endoscopy, Digestive System / Q000009:adverse effects* / Q000379:methods*; D005260:Female; D006321:Heart / Q000502:physiology*; D006339:Heart Rate; D006801:Humans; D007564:Japan; D008168:Lung / Q000502:physiology*; D008297:Male; D008875:Middle Aged; D009055:Mouth; D009666:Nose