title: [The experimental study of lipo-sodium morrhuate promoting apoptosis of ECV-304 cells].
abstract: OBJECTIVE
  To evaluate the effect of lipo-sodium morrhuate on ECV-304 cell line.
  
  
  METHODS
  The effect lipo-sodium morrhuate was evaluated by toxicology trial (MTT), electron microscope, DNA electrophoresis and flow cytometer.
  
  
  RESULTS
  The toxicology results showed, that the number of vital cells in lipo-sodium morrhuate group decreased slowly. The electron microscope exhibited apoptosis in the lipo-sodium morrhuate group. And there were typical DNA ladder in DNA electrophoresis and typical apoptosis peak in flow cytometer. The apoptosis rate was 22.23%.
  
  
  CONCLUSIONS
  Unlike the normal preparation of sodium morrhuate, lipo-sodium morrhuate could induce apoptosis of ECV-304 cell line.
authors.affiliation: Department of Oral and Maxillofacial Surgery, School of Stomatology, Xi'an Jiao Tong University, Xi'an 710004, China. yzhqun@mail.xjtu.edu.cn
authors.forename: Zhuang-qun
authors.initials: ZQ
authors.lastname: Yang
authors.forename: Hai-long
authors.initials: HL
authors.lastname: Lan
authors.forename: Jun-bo
authors.initials: JB
authors.lastname: Tu
authors.forename: Yong
authors.initials: Y
authors.lastname: Song
authors.forename: Tie-liang
authors.initials: TL
authors.lastname: Zhang
authors.forename: Zhe
authors.initials: Z
authors.lastname: Xing
mesh_terms: D017209:Apoptosis / Q000187:drug effects; D049109:Cell Proliferation / Q000187:drug effects; D002478:Cells, Cultured; D042783:Endothelial Cells / Q000473:pathology*; D006801:Humans; D008081:Liposomes; D012976:Sodium Morrhuate / Q000494:pharmacology*; D014471:Umbilical Veins / Q000166:cytology*
chemical_list: D008081:Liposomes; D012976:Sodium Morrhuate