title: [Preparation and studies of the adsorbent double cross-linked agar beads entrapped attapulgite clay].
abstract: A method for preparing the double cross-linked agar beads entrapped attapulgite clay for hemopurification is reported. Attapulgite clay was coated with agar and cross-linked by epichlorohydrin. After the process of "drying-out", the cross-linked agar beads entrapped attapulgite clay (CAA) was cross-linked again by 10% toluene 2,4,-diisocyanate in acetone at 35 degrees C for 3 h and 30 min. The products withstood autoclaving at 121 degrees C for 30 min. The performance tests showed that the adsorption of the double cross-linked agar beads entrapped attapulgite clay (DCAA) on methylene blue was about 4 times the adsorption of CAA on methylene blue. The intensity of DCAA was raised 6 times, and the appearance of DCAA was denser. Investigation on the blood being in contact with DCAA showed: at 1 h of contact, the loss of leucocyte was <1%, of erythrocyte <5%, and of blood platelets <8%; at 2h of contact, the loss of leucocyte was <2%, of erythrocyte <10%, and of blood platelets <20%.
authors.affiliation: Department of Chemistry, Chongqing Jiaotong University, Chongqing 400074, China. mayu-he@sina.com
authors.forename: Yu
authors.initials: Y
authors.lastname: Ma
authors.forename: Xiaolan
authors.initials: X
authors.lastname: Yang
authors.forename: Wei
authors.initials: W
authors.lastname: Huang
mesh_terms: D000327:Adsorption; D000362:Agar; D000818:Animals; D001672:Biocompatible Materials; D004811:Epichlorohydrin / Q000737:chemistry*; D006464:Hemoperfusion / Q000295:instrumentation*; D017616:Magnesium Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D008422:Materials Testing; D051381:Rats; D017655:Silicon Compounds / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D001672:Biocompatible Materials; D017616:Magnesium Compounds; D017655:Silicon Compounds; D004811:Epichlorohydrin; D000362:Agar; C026325:attapulgite