title: Long-term survival of a pulmonary artery sarcoma produced by aggressive surgical resection and adjuvant chemoradiotherapy.
abstract: Malignant pulmonary artery tumors represented by sarcomas are rare, but fatal. Early diagnosis and radical surgical resection offer the only chance for survival. However, surgical intervention has some challenging aspects, and prognosis is poor even after tumor resection. We report a case of a pulmonary artery sarcoma between the right ventricular outflow tract and the pulmonary artery branches. The tumor was aggressively extracted with reconstruction using a cryopreserved pulmonary valved allograft, followed by adjuvant chemoradiotherapy. At 56 months after surgery, the patient is well without any evidence of recurrence, demonstrating that aggressive surgical resection with adjuvant chemoradiotherapy can prolong survival.
authors.affiliation: Department of Cardiovascular Surgery, National Cardiovascular Center, Osaka, Japan.
authors.forename: Atsushi
authors.initials: A
authors.lastname: Nakahira
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Ogino
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Sasaki
authors.forename: Nobuyuki
authors.initials: N
authors.lastname: Katakami
mesh_terms: D000328:Adult; D000970:Antineoplastic Agents / Q000627:therapeutic use; D000972:Antineoplastic Agents, Phytogenic / Q000627:therapeutic use; D016190:Carboplatin / Q000627:therapeutic use; D017024:Chemotherapy, Adjuvant / Q000379:methods; D006801:Humans; D008297:Male; D017239:Paclitaxel / Q000627:therapeutic use; D011651:Pulmonary Artery / Q000601:surgery*; D018714:Radiotherapy, Adjuvant / Q000379:methods; D012509:Sarcoma / Q000601:surgery / Q000628:therapy*; D016896:Treatment Outcome; D019043:Vascular Neoplasms / Q000601:surgery / Q000628:therapy*
chemical_list: D000970:Antineoplastic Agents; D000972:Antineoplastic Agents, Phytogenic; D016190:Carboplatin; D017239:Paclitaxel