title: Progressive localized retinal nerve fiber layer loss following a retinal cotton wool spot.
abstract: Localized retinal nerve fiber layer (RNFL) defects can be an early sign of glaucomatous damage. However, their presence is not pathognomonic of the disease. We report a case of a localized RNFL defect developing after a retinal cotton-wool spot in a patient with diabetes mellitus and systemic hypertension.
authors.affiliation: Hamilton Glaucoma Center and Department of Ophthalmology, University of California, San Diego, CA, USA.
authors.forename: Luciana M
authors.initials: LM
authors.lastname: Alencar
authors.forename: Felipe A
authors.initials: FA
authors.lastname: Medeiros
authors.forename: Robert
authors.initials: R
authors.lastname: Weinreb
mesh_terms: D000368:Aged; D003924:Diabetes Mellitus, Type 2 / Q000150:complications; D005902:Glaucoma, Open-Angle / Q000150:complications* / Q000473:pathology / Q000503:physiopathology; D006801:Humans; D006973:Hypertension / Q000150:complications; D008297:Male; D009412:Nerve Fibers / Q000473:pathology*; D009898:Optic Disk / Q000473:pathology; D012160:Retina / Q000473:pathology*; D012164:Retinal Diseases / Q000209:etiology* / Q000473:pathology*; D014794:Visual Fields