title: Sequential bilateral solitary extramedullary plasmacytoma of the ciliary body.
abstract: OBJECTIVE
  To report bilateral plasmacytoma of the ciliary body in a healthy patient.
  
  
  METHODS
  Clinicopathologic report.
  
  
  RESULTS
  A 55-year-old woman with iritis developed an iridociliary mass in the left eye. Systemic evaluation was normal. Fine-needle aspiration (FNAB) of the mass revealed atypical, binucleate plasmacytoid cells with positive leukocyte common antigen staining, suggestive of plasmacytoma. The tumor was treated with 4000 cGy by using custom-designed plaque radiotherapy. The tumor completely resolved. Two years later, a similar iridociliary mass was noted in the right eye, and FNAB confirmed plasmacytoma. Plaque radiotherapy of 4000 cGy was delivered. At the 3-year follow-up, there has been no local recurrence or evidence of systemic multiple myeloma or monoclonal gammopathy.
  
  
  CONCLUSIONS
  Extramedullary plasmacytoma can involve the uvea and rarely manifest multiplicity. Long-term monitoring for systemic plasma cell dyscrasia is warranted.
authors.affiliation: Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, PA 19107, USA. carol.shields@shieldsoncology.com
authors.forename: Carol L
authors.initials: CL
authors.lastname: Shields
authors.forename: William H
authors.initials: WH
authors.lastname: Chong
authors.forename: Hormoz
authors.initials: H
authors.lastname: Ehya
authors.forename: Jerry A
authors.initials: JA
authors.lastname: Shields
mesh_terms: D014408:Biomarkers, Tumor / Q000032:analysis; D044963:Biopsy, Fine-Needle; D001918:Brachytherapy; D002924:Ciliary Body / Q000000981:diagnostic imaging / Q000473:pathology* / Q000528:radiation effects; D005260:Female; D006801:Humans; D033401:Microscopy, Acoustic; D008875:Middle Aged; D010954:Plasmacytoma / Q000737:chemistry / Q000000981:diagnostic imaging / Q000473:pathology* / Q000532:radiotherapy; D014604:Uveal Neoplasms / Q000737:chemistry / Q000000981:diagnostic imaging / Q000473:pathology* / Q000532:radiotherapy
chemical_list: D014408:Biomarkers, Tumor