title: [Clinical features of spontaneous spinal epidural hematoma and influential factors of its prognosis].
abstract: OBJECTIVE
  To explore the clinical features of spontaneous spinal epidural hematoma (SSEH) and to find out factors influencing its prognosis.
  
  
  METHODS
  From September 1998 to October 2006, 23 patients with SSEH (10 males and 13 females) were treated. Their ages ranged from 10 to 69 years. The primary neurological status were classified as grade A in 7 patients, B in 2 patients, C in 4 patients, D in 9 patients and E in 1 patients according to ASIA grading system. The progressive intervals of their symptoms were divided as four period: less than 12 hours (12 patients), 12 to 24 hours (2 patients), 24 to 48 hours (3 patients) and more than 48 hours (6 patients). SSEH was diagnosed by MRI or by histopathological examination. The cases history, laboratory examination, radiological image, treatment, pathological result and prognosis were recorded and analyzed after 3 month.
  
  
  RESULTS
  In 23 patients, there were 1 case of deterioration, 8 cases of no change, 9 cases of improvement and 5 cases of complete recovery. The gender had no correlation with prognosis (P>0.05). In the patients who had shorter progressive interval and more severe edema of spinal cord, the prognosis was worse (P<0.05). In the patients who had mild neurological deficit, the prognosis was good (P<0.01). In 17 patients undergoing surgery, the scores for prognosis was 1 point in 1 case, 2 points in 5 cases, 3 points in 6 cases and 4 points in 5 cases; the operation time had no correlation with prognosis (r = 0.056, P>0.05). In 6 patients undergoing conservative treatment, the scores for prognosis were 2 points and 3 points in 3 cases respectively.
  
  
  CONCLUSIONS
  Prognosis of patient with SSEH is influenced by his primary neurological status, progressive interval, spinal edema and size of hematoma. The major treatment is surgical evacuation of hematoma as early as possible to break the aggravation of spinal function. Conservative treatment is not considered unless the neurological defects recovered in the early period.
authors.affiliation: Department of Neurosurgery, West China Hospital, Sichuan University, Chengdu Sichuan, 610041, P. R. China.
authors.forename: Zhan
authors.initials: Z
authors.lastname: Liu
authors.forename: Qingfang
authors.initials: Q
authors.lastname: Jiao
authors.forename: Xiang
authors.initials: X
authors.lastname: Wang
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D005260:Female; D046748:Hematoma, Epidural, Spinal / Q000175:diagnosis* / Q000188:drug therapy / Q000503:physiopathology / Q000601:surgery*; D006801:Humans; D007796:Laminectomy; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D011239:Prednisolone / Q000627:therapeutic use; D011379:Prognosis; D012189:Retrospective Studies; D012307:Risk Factors; D012720:Severity of Illness Index; D013116:Spinal Cord / Q000473:pathology / Q000601:surgery*; D013117:Spinal Cord Compression / Q000175:diagnosis / Q000209:etiology / Q000601:surgery; D055815:Young Adult
chemical_list: D011239:Prednisolone