title: Power Doppler ultrasonography of the feeding arteries of the prostate gland: a novel approach to the diagnosis of prostate cancer?
abstract: OBJECTIVE
  The purpose of this study was to assess the role of spectral Doppler ultrasonographic parameters of the feeding arteries of the prostate for the detection of prostate cancer.
  
  
  METHODS
  A total of 55 patients referred for prostate biopsy with a mean age of 66.4 years (range, 46-82 years) were included. In each patient, Doppler indices from bilateral capsular and urethral arteries were obtained. The indices were compared with regard to malignant (group A) and benign (group B) subgroups of histopathologic outcomes of transrectal ultrasonographically guided prostate biopsy for each side (n = 19 and n = 91 for groups A and B, respectively) and to assess whether the indices were significantly altered on the side with cancer compared with the contralateral side.
  
  
  RESULTS
  The mean pulsatility index value for the capsular artery of group A (1.49 +/- 0.57) was significantly lower than that of group B (1.71 +/- 0.52; P = .048). The mean resistive index and systolic/diastolic ratio for the capsular artery of group A (0.78 +/- 0.10 and 5.40 +/- 2.74, respectively) were lower than those of group B (0.82 +/- 0.08 and 7.40 +/- 4.91) despite being statistically insignificant (P = .075 and .119, respectively).
  
  
  CONCLUSIONS
  Spectral waveform measurements by power Doppler transrectal ultrasonography may be useful in differentiating prostate cancer from benign hypertrophy. Further research is needed to elucidate the potential of spectral Doppler indices of the capsular and urethral arteries.
authors.affiliation: Department of Radiology, Ankara Training and Research Hospital, Ankara, Turkey. ahmettuncayturgut@yahoo.com
authors.forename: Ahmet Tuncay
authors.initials: AT
authors.lastname: Turgut
authors.forename: Esin
authors.initials: E
authors.lastname: Olçücüoglu
authors.forename: Pinar
authors.initials: P
authors.lastname: Koşar
authors.forename: Pinar Ozdemir
authors.initials: PO
authors.lastname: Geyik
authors.forename: Ugur
authors.initials: U
authors.lastname: Koşar
authors.forename: Vikram
authors.initials: V
authors.lastname: Dogra
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001158:Arteries / Q000000981:diagnostic imaging; D001707:Biopsy, Needle; D001794:Blood Pressure / Q000502:physiology; D003937:Diagnosis, Differential; D006801:Humans; D008297:Male; D008875:Middle Aged; D009929:Organ Size; D011467:Prostate / Q000098:blood supply* / Q000000981:diagnostic imaging; D017430:Prostate-Specific Antigen / Q000032:analysis; D011470:Prostatic Hyperplasia / Q000175:diagnosis / Q000473:pathology; D019048:Prostatic Intraepithelial Neoplasia / Q000175:diagnosis / Q000473:pathology; D011471:Prostatic Neoplasms / Q000175:diagnosis* / Q000473:pathology; D011472:Prostatitis / Q000175:diagnosis / Q000473:pathology; D011673:Pulsatile Flow / Q000502:physiology; D018608:Ultrasonography, Doppler; D018615:Ultrasonography, Doppler, Color; D018084:Ultrasonography, Interventional; D014521:Urethra / Q000098:blood supply; D014655:Vascular Resistance / Q000502:physiology
chemical_list: D017430:Prostate-Specific Antigen