Efficacy of bupropion in the treatment of pemoline dependence.
We present the case of a woman who requested psychiatric evaluation because she had been taking pemoline for six months at a dose between 100-150 mg/day, and was finding it difficult to discontinue taking this substance. Initiation of 300 mg/day of bupropion solved the patient's dependence problem. We propose using antidepressants such as bupropion for the treatment of addictive behaviors due to central nervous system stimulants.
Martín Morgado
B
B
Psychiatry Department, Hospital Universitario Infanta Cristina, Badajoz, Spain. bemar_5@hotmail.com
Vaz Leal
F J
FJ
Bolívar Perálvarez
M
M
Guisado Macías
J A
JA
D016642:Bupropion / Q000627:therapeutic use*; D000697:Central Nervous System Stimulants / Q000008:administration & dosage; D018765:Dopamine Uptake Inhibitors / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008875:Middle Aged; D010389:Pemoline / Q000008:administration & dosage; D019966:Substance-Related Disorders / Q000188:drug therapy*; D016896:Treatment Outcome
D000697:Central Nervous System Stimulants; D018765:Dopamine Uptake Inhibitors; D016642:Bupropion; D010389:Pemoline