title: Genetic profile of two Tibetan populations from China by analysis of 15 STR loci.
abstract: Allele frequency data for the STR systems D3S1358, TH01, D21S11, D18S51, PENTAE, D5S818, D13S317, D7S820, D16S539, CSF1PO, PENTAD, VWA, D8S1179, TPOX, and FGA were determined in two population samples of unrelated, healthy Tibetan individuals. All loci met Hardy-Weinberg expectations, and there was no evidence of association of alleles among the 15 loci. These findings suggest that these STR loci could be particularly powerful tools in forensic medicine and could provide the necessary fundamental population genetic data for the reconstruction of recent human evolutionary history.
authors.affiliation: Department of Respiratory Medicine and National Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu 610041, Sichuan, People's Republic of China.
authors.forename: Binwu
authors.initials: B
authors.lastname: Ying
authors.forename: Tingting
authors.initials: T
authors.lastname: Liu
authors.forename: Guo
authors.initials: G
authors.lastname: Chen
authors.forename: Zhihe
authors.initials: Z
authors.lastname: Zhao
authors.forename: Hong
authors.initials: H
authors.lastname: Fan
authors.forename: Fuqiang
authors.initials: F
authors.lastname: Wen
mesh_terms: D000483:Alleles; D044466:Asian People / Q000208:ethnology / Q000235:genetics*; D002681:China; D003469:Culture; D005787:Gene Frequency; D005819:Genetic Markers; D005828:Genetics, Population; D005838:Genotype; D005843:Geography; D006454:Hemoglobins / Q000235:genetics*; D006801:Humans; D018895:Microsatellite Repeats / Q000235:genetics*; D011110:Polymorphism, Genetic / Q000235:genetics*; D040641:Quantitative Trait Loci / Q000235:genetics; D018609:Tibet / Q000208:ethnology
chemical_list: D005819:Genetic Markers; D006454:Hemoglobins