title: Self-sorting chiral subcomponent rearrangement during crystallization.
abstract: The incorporation of enantiopure 1-amino-2,3-propanediol as a subcomponent into a dicopper double helicate resulted in perfect chiral induction of the helicate's twist. DFT calculations allowed the determination of the helicity of the complex in solution. The same helical induction, in which S amines induced a Lambda helical twist, was observed in the solid state by X-ray crystallography. Electronic structure calculations also revealed that the unusual deep green color of this class of complexes was due to a metal-to-ligand charge transfer excitation, in which the excited state possesses a valence delocalized Cu2(3+) core. The use of a racemic amine subcomponent resulted in the formation of a dynamic library of six diastereomeric pairs of enantiomers. Surprisingly, this library converted into a single pair of enantiomers during crystallization. We were able to observe this process reverse upon redissolution, as initial ligand exchange was followed by covalent imine metathesis.
authors.affiliation: Department of Organic Chemistry, University of Geneva, 30 Quai Ernest Ansermet, 1211 Genève 4, Switzerland.
authors.forename: Marie
authors.initials: M
authors.lastname: Hutin
authors.forename: Christopher J
authors.initials: CJ
authors.lastname: Cramer
authors.forename: Laura
authors.initials: L
authors.lastname: Gagliardi
authors.forename: Abdul Rehaman Moughal
authors.initials: AR
authors.lastname: Shahi
authors.forename: Gérald
authors.initials: G
authors.lastname: Bernardinelli
authors.forename: Radovan
authors.initials: R
authors.lastname: Cerny
authors.forename: Jonathan R
authors.initials: JR
authors.lastname: Nitschke