title: [Predictive factors of failure extubation among preterm infants].
abstract: OBJECTIVE
  To determine the factors that lead to extubation failure among preterm newborns (PTN).
  
  
  METHODS
  Failure was determined when patients had to be reintubated during the first 72 hours. Critically-ill preterm newborns needing mechanical assisted ventilation at least during 24 hours were studied prospectively. Two groups were included: Group A, who failed in extubation for the first time and Group B, a control group who did not fail. Significance was set a p <0.05.
  
  
  RESULTS
  Gestational age and birth weight showed significant differences in Group B (control group). Significant factors in the multivariate analysis were gestational age < 32 weeks, caloric intake < or = 100 calories/kg/day and mean airway pressure (MAP) > or = [corrected] 4.5 cm H2O.
  
  
  CONCLUSIONS
  According to our results, an extubation should be planned whenever a patient is a PTN, has a gestational age of <32 weeks, a caloric intake >100 cal/kg/day, and its ventilator MAP is <4.5 cm H2O.
authors.affiliation: Servicio de Neonatología de la Unidad Médica de Alta Especialidad Hospital General Dr. Gaudencio González Garza, Centro Médico Nacional La Raza, Instituto Mexicano del Seguro Social, México, D.F., México. tapiachar@yahoo.com.mx
authors.forename: Carlos Antonio
authors.initials: CA
authors.lastname: Tapia-Rombo
authors.forename: Angel Melquíades
authors.initials: AM
authors.lastname: Galindo-Alvarado
authors.forename: Víctor Joel
authors.initials: VJ
authors.lastname: Saucedo-Zavala
authors.forename: Maria Luisa
authors.initials: ML
authors.lastname: Cuevas-Urióstegui
mesh_terms: D001724:Birth Weight; D016022:Case-Control Studies; D016638:Critical Illness / Q000628:therapy; D005260:Female; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D008297:Male; D015999:Multivariate Analysis; D011446:Prospective Studies; D012121:Respiration, Artificial; D019233:Retreatment