In vivo evaluation of titanium implants coated with bioactive glass by pulsed laser deposition.
During the past years, different techniques, like chemical treatment, plasma spraying, sputtering, enamelling or sol-gel; and materials, like metals, hydroxylapatite, calcium phosphates, among others, have been applied in different combinations to improve the performance of prostheses. Among the techniques, Pulsed Laser Deposition (PLD) is very promising to produce coatings of bioactive glass on any metal alloy used as implant. In this work the biocompatibility of PLD coatings deposited on titanium substrates was examined by implantation in vivo. Different coating compositions were checked to find the most bioactive that was then applied on titanium and implanted into paravertebral muscle of rabbit.
Borrajo
Jacinto P
JP
Departamento de Física Aplicada, ETSE Industriais e Minas, Lagoas-Marcosende, Universidade de Vigo, Vigo 36200, Spain. jpb@uvigo.es
Serra
Julia
J
González
Pío
P
León
Betty
B
Muñoz
Fernando M
FM
López
M
M
D000497:Alloys; D000818:Animals; D020099:Coated Materials, Biocompatible / Q000009:adverse effects / Q000138:chemical synthesis* / Q000737:chemistry*; D004595:Electroplating / Q000379:methods*; D005260:Female; D005898:Glass / Q000737:chemistry*; D007834:Lasers; D008422:Materials Testing; D019736:Prostheses and Implants / Q000009:adverse effects; D011817:Rabbits; D012822:Silicon Dioxide / Q000737:chemistry; D014025:Titanium / Q000009:adverse effects / Q000737:chemistry
D000497:Alloys; D020099:Coated Materials, Biocompatible; C031462:titanium alloy (TiAl6V4); D012822:Silicon Dioxide; D014025:Titanium