title: Ruptured cerebral aneurysm complicated with rebleeding following thrombolysis during endovascular embolization: two case reports.
abstract: A 68-year-old woman and a 42-year-old woman presented with subarachnoid hemorrhage due to rupture of cerebral aneurysm. Both patients were treated with endovascular coil embolization. Thromboembolic complications occurred during the procedure and local thrombolysis was performed for recanalization. One patient developed massive rebleeding immediately after the procedure and the other suffered minor hemorrhage adjacent to the embolized aneurysm 2 days later. Local thrombolysis during treatment of ruptured aneurysm by coil embolization carries a significant risk of rebleeding. Prevention of thromboembolic complication by adequate heparinization is important.
authors.affiliation: Department of Neurosurgery, Nagasaki University School of Medicine, Nagasaki, Japan.
authors.forename: Kentaro
authors.initials: K
authors.lastname: Hayashi
authors.forename: Hideaki
authors.initials: H
authors.lastname: Takahata
authors.forename: Naoki
authors.initials: N
authors.lastname: Kitagawa
mesh_terms: D000328:Adult; D000368:Aged; D001921:Brain / Q000000981:diagnostic imaging / Q000473:pathology / Q000503:physiopathology; D002533:Cerebral Angiography; D002536:Cerebral Arteries / Q000000981:diagnostic imaging / Q000473:pathology / Q000503:physiopathology; D004621:Embolization, Therapeutic / Q000009:adverse effects* / Q000295:instrumentation / Q000401:mortality; D017809:Fatal Outcome; D005260:Female; D005343:Fibrinolytic Agents / Q000009:adverse effects*; D006801:Humans; D002532:Intracranial Aneurysm / Q000628:therapy*; D019106:Postoperative Hemorrhage / Q000139:chemically induced / Q000503:physiopathology; D019736:Prostheses and Implants / Q000009:adverse effects; D012008:Recurrence; D013345:Subarachnoid Hemorrhage / Q000139:chemically induced / Q000503:physiopathology / Q000628:therapy*; D013346:Subarachnoid Space / Q000000981:diagnostic imaging / Q000473:pathology / Q000503:physiopathology; D013923:Thromboembolism / Q000150:complications* / Q000188:drug therapy / Q000503:physiopathology; D014057:Tomography, X-Ray Computed
chemical_list: D005343:Fibrinolytic Agents