title: Histologic comparison of light emitting diode phototherapy-treated hydroxyapatite-grafted extraction sockets: a same-mouth case study.
abstract: BACKGROUND
  The stimulating effect of red and near-infrared (NIR) laser phototherapy on bone regeneration and growth has been shown in a number of in vitro and animal studies. However, the effect of NIR phototherapy on the bone regeneration of hydroxyapatite (HA) -treated extraction sockets has not been previously demonstrated.
  
  
  METHODS
  An investigational Biolux extraoral light emitting diode phototherapy device was used daily for 21 days postextraction and socket grafting with HA (Osteograf LD300) unilaterally. Bone regeneration of the phototherapy-treated and nontreated side was compared in same-mouth extraction sockets.
  
  
  RESULTS
  Histologic evaluations showed enhanced bone formation and faster particle resorption associated with the phototherapy-treated socket graft compared with the non-phototherapy-treated socket.
  
  
  CONCLUSIONS
  The accelerated bone healing in the phototherapy-treated HA socket graft may provide faster implant placement compared to non-phototherapy-treated socket grafts.
authors.affiliation: 343 Railway Street, Vancouver, British Columbia, Canada. brawn_peter@yahoo.ca
authors.forename: Peter R
authors.initials: PR
authors.lastname: Brawn
authors.forename: Alan
authors.initials: A
authors.lastname: Kwong-Hing
mesh_terms: D020341:Absorbable Implants; D001861:Bone Regeneration / Q000528:radiation effects; D018786:Bone Substitutes / Q000528:radiation effects / Q000627:therapeutic use*; D017886:Durapatite / Q000528:radiation effects / Q000627:therapeutic use*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D028022:Low-Level Light Therapy / Q000379:methods*; D008334:Mandible / Q000601:surgery; D008875:Middle Aged; D008963:Molar / Q000601:surgery; D010012:Osteogenesis / Q000528:radiation effects; D011879:Radiotherapy Dosage; D014081:Tooth Extraction; D020390:Tooth Socket / Q000528:radiation effects / Q000601:surgery*; D014945:Wound Healing / Q000528:radiation effects
chemical_list: D018786:Bone Substitutes; D017886:Durapatite