[Budd-Chiari syndrome and severe thrombocytopenia in a patient with Systemic Lupus Erythematosus and Secondary Antiphospholipid Syndrome].
Systemic Lupus Erythematosus (SLE) is a rheumatic autoimmune disease characterized by multisystemic involvement with a variable prognosis. The association with Antiphospholipid Syndrome (APS) occurs in about 36% of the patients, raising additional problems with treatment and monitoring of these patients. The authors report a clinical case of a girl with SLE and APS who represented Budd-Chiari Syndrome and severe thrombocytopenia. The patient had severe thrombotic event and simultaneously a high hemorrhagic risk due to thrombocytopenia. Long-term resolution of the thrombocytopenia was achieved with mycophenolate mofetil. Long-term anticoagulation for thrombosis prophylaxis is required.
Duarte
Cátia
C
Interno Complementar de Reumatologia dos Hospitais da Universidade de Coimbra. catiamduarte@mail.com
Couto
Maura
M
Inês
Luís
L
Malcata
Armando
A
D000293:Adolescent; D016736:Antiphospholipid Syndrome / Q000209:etiology*; D006502:Budd-Chiari Syndrome / Q000209:etiology*; D005260:Female; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications*; D012720:Severity of Illness Index; D013921:Thrombocytopenia / Q000209:etiology*