title: Percutaneous left ventricular assist devices in acute myocardial infarction complicated by cardiogenic shock.
abstract: Cardiogenic shock (CS) remains the most common cause of death in patients with acute myocardial infarction (AMI). In addition to percutaneous coronary intervention, inotropes, and fluids, intraaortic balloon pumping (IABP) is most widely used for initial haemodynamic stabilization. However, the main limitation of IABP is the lack of active circulatory support and the requirement of a certain level of left ventricular (LV) function. In many patients with severe depression of LV function, haemodynamic support and LV unloading derived from IABP is insufficient to reverse CS. The use of percutaneous LV assist devices (LVAD) with active circulatory support might be beneficial in CS patients not responding to standard treatment including IABP support. This review reports the current experience of percutaneous LVAD in CS complicating AMI.
authors.affiliation: Department of Internal Medicine/Cardiology, University of Leipzig--Heart Center, Strümpellstr. 39, 04289 Leipzig, Germany. thielh@medizin.uni-leipzig.de
authors.forename: Holger
authors.initials: H
authors.lastname: Thiele
authors.forename: Richard W
authors.initials: RW
authors.lastname: Smalling
authors.forename: Gerhard C
authors.initials: GC
authors.lastname: Schuler
mesh_terms: D002315:Cardiopulmonary Bypass / Q000379:methods*; D006353:Heart-Assist Devices; D006801:Humans; D009203:Myocardial Infarction / Q000150:complications / Q000628:therapy*; D012770:Shock, Cardiogenic / Q000150:complications / Q000628:therapy*