Fluoride ion-catalyzed 1,2-desilylative defluorination: syntheses of 1-substituted 2,2-difluorostyrenes.
1-(3'-Chlorophenyl)-1-trimethylsilyl-1,2,2,2-tetrafluoroethane has been prepared in an excellent yield by the Mg-promoted defluorinative silylation of 3-chloropentafluoroethylbenzene and transformed to a series of 1-substituted 2,2-difluorostyrenes by fluoride ion-catalyzed 1,2-desilylative defluorination.
Nakamura
Yutaka
Y
Department of Applied Chemistry, Faculty of Engineering, Okayama University, Okayama 700-8530, Japan.
Uneyama
Kenji
K