title: Emergence of panniculitis and haemophagocytic syndrome in a patient with chronic systemic lupus erythematosus.
abstract: Panniculitis rarely occurs in the course of systemic lupus erythematosus (SLE). When it occurs, it is thought to be mainly lupus erythematosus panniculitis (LEP). Here we describe a 32-year old Japanese woman with chronic SLE, who simultaneously presented facial lymphocytic lobular panniculitis and pancytopenia due to haemophagocytic syndrome. She showed several auto-antibodies against trilineage haematopoetic cells, an anti-cardiolipin antibody, and no evidence of viral infection, indicating that her haemophagocytic syndrome might be autoimmune-associated haemophagocytic syndrome. The panniculitis and haemophagocytic syndrome presented simultaneously, and these manifestations were dramatically improved with corticosteroid therapy; therefore, the lymphocytic lobular panniculitis could be linked to autoimmune-associated haemophagocytic syndrome in this case.
authors.affiliation: The Department of Medicine, Shiga University of Medical Science, Seta, Otsu, Japan.
authors.forename: N
authors.initials: N
authors.lastname: Deji
authors.forename: T
authors.initials: T
authors.lastname: Sugimoto
authors.forename: T
authors.initials: T
authors.lastname: Fujimoto
authors.forename: M
authors.initials: M
authors.lastname: Aoyama
authors.forename: N
authors.initials: N
authors.lastname: Takeda
authors.forename: M
authors.initials: M
authors.lastname: Sakaguchi
authors.forename: T
authors.initials: T
authors.lastname: Uzu
authors.forename: A
authors.initials: A
authors.lastname: Kashiwagi
mesh_terms: D000328:Adult; D001706:Biopsy; D002908:Chronic Disease; D004630:Emergencies; D005260:Female; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications* / Q000473:pathology* / Q000601:surgery; D015435:Panniculitis, Lupus Erythematosus / Q000150:complications* / Q000473:pathology* / Q000601:surgery