title: [Diagnosis and treatment of pulmonary histoplasmoma: report of 3 cases].
abstract: OBJECTIVE
  To investigate the diagnosis and treatment of pulmonary histoplasmoma.
  
  
  METHODS
  The clinical data of 3 patients with pulmonary histoplasmoma. 2 males, both 49-years-old, and 1 female, 27-years-old, were analyzed.
  
  
  RESULTS
  Nodules in the lung, regardless solitary or multiple, with clear border and calcification, were the first radiological finding. All 3 patients were misdiagnosed as with tuberculosis or primary or metastatic lung neoplasm and underwent operation. The diagnosis was confirmed after surgery. Pathological examination showed caseous necrosis and a great amount of histoplasma in the multinuclear cells. Follow-up lasting 1, 2, and 3 years respectively showed no recurrence.
  
  
  CONCLUSIONS
  Pulmonary nodule, regardless solitary or multiple, with clear border and calcification, is the first radiological finding of pulmonary histoplasmoma Autopsy is necessary for diagnosis of pulmonary histoplasmoma, difficult to diagnose, however, with a good prognosis.
authors.affiliation: Department of Thoracic Surgery, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, China.
authors.forename: Gang
authors.initials: G
authors.lastname: Shen
authors.forename: Ying
authors.initials: Y
authors.lastname: Chai
authors.forename: Guo-Fei
authors.initials: GF
authors.lastname: Zhang
authors.forename: Hong-Quan
authors.initials: HQ
authors.lastname: Wei
authors.forename: Lan
authors.initials: L
authors.lastname: Yue
mesh_terms: D000328:Adult; D005260:Female; D005500:Follow-Up Studies; D006658:Histoplasma; D006660:Histoplasmosis / Q000175:diagnosis* / Q000382:microbiology; D006801:Humans; D008168:Lung / Q000382:microbiology / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies