title: [Rational treatment of first-degree burns].
abstract: First-degree burns are the most common type of burn, but are often inadequately treated. The methods of treatment and the course of healing are poorly documented owing to the fact that first-degree burns are generally not considered to be a serious injury. First-degree burns can be caused by thermal injury or UV irradiation (sunburn). The pathophysiology and the therapeutic approach are similar, although the damage follows a different time course for each injury--immediate damage after contact with hot objects, liquids or fire, delayed damage after sun exposure. After initial cooling with water, aqueous emulsions with small amounts of well-tolerated lipids (O/W emulsions) are best suited for treating first-degree burns or sunburn. Water evaporates producing cooling and reducing inflammation; the lipids accelerate the repair of the damaged skin barrier and reduce drying. Foam sprays and lotions are ideal because they are easy and painless to apply. The use of topical corticosteroids is not recommended, as superiority to the vehicle has not been shown.
authors.affiliation: Universitäts-Hautklinik, Schittenhelmstrasse 7, 24105 Kiel, Germany. eproksch@dermatology.uni-kiel.de
authors.forename: E
authors.initials: E
authors.lastname: Proksch
authors.forename: J-M
authors.initials: JM
authors.lastname: Jensen
authors.forename: A
authors.initials: A
authors.lastname: Crichton-Smith
authors.forename: A
authors.initials: A
authors.lastname: Fowler
authors.forename: J
authors.initials: J
authors.lastname: Clitherow
mesh_terms: D000305:Adrenal Cortex Hormones / Q000008:administration & dosage; D000328:Adult; D000700:Analgesics / Q000008:administration & dosage; D002056:Burns / Q000628:therapy*; D002675:Child, Preschool; D003080:Cold Temperature; D006633:Histamine Antagonists / Q000627:therapeutic use; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D009824:Ointments; D010936:Plant Extracts / Q000627:therapeutic use; D012867:Skin / Q000473:pathology; D013471:Sunburn / Q000145:classification / Q000188:drug therapy / Q000209:etiology / Q000473:pathology / Q000503:physiopathology / Q000628:therapy*; D013997:Time Factors; D014466:Ultraviolet Rays / Q000009:adverse effects; D014945:Wound Healing
chemical_list: D000305:Adrenal Cortex Hormones; D000700:Analgesics; D006633:Histamine Antagonists; D009824:Ointments; D010936:Plant Extracts