Role of Krüppel-like transcription factors in endothelial biology.
Krüppel-like factors are members of the zinc finger family of transcription factors that have been implicated as playing key roles in regulating cellular differentiation and tissue development. Studies over the past several years support an important role for this family of factors in vascular biology. This review summarizes the role of Krüppel-like factors in endothelial cell biology.
Atkins
G Brandon
GB
Cardiovascular Research Institute, Case Western Reserve University, Cleveland, OH 44106, USA.
Jain
Mukesh K
MK
D000818:Animals; D002454:Cell Differentiation / Q000502:physiology; D002465:Cell Movement / Q000502:physiology; D049109:Cell Proliferation; D004730:Endothelium, Vascular / Q000502:physiology*; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000494:pharmacology; D000090062:Kruppel-Like Factor 4; D000075723:Kruppel-Like Factor 6; D051741:Kruppel-Like Transcription Factors / Q000502:physiology*; D051379:Mice; D018345:Mice, Knockout; D009389:Neovascularization, Pathologic / Q000503:physiopathology; D011518:Proto-Oncogene Proteins / Q000502:physiology
D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; C096161:KLF2 protein, human; C105465:KLF6 protein, human; C498314:Klf2 protein, mouse; D000090062:Kruppel-Like Factor 4; D000075723:Kruppel-Like Factor 6; D051741:Kruppel-Like Transcription Factors; D011518:Proto-Oncogene Proteins