Analysis of bovine immunoglobulin G in milk, colostrum and dietary supplements: a review.
The immunoprotective properties of bovine milk immunoglobulin G (IgG) have led to a recent proliferation of nutritional products incorporating this protein. It has therefore become critical that reliable analytical techniques for the measurement of the IgG content in such products are available. This literature review surveys current methods of analysis for IgG, including separation-based or immuno-based concentration analysis. The review also discusses nutraceutical applications, regulatory issues, stability of IgG and the significance of primary reference material in IgG analysis.
Gapper
Leyton W
LW
Fonterra Research Centre, Dairy Farm Road, Private Bag 11029, Palmerston North, New Zealand.
Copestake
David E J
DE
Otter
Don E
DE
Indyk
Harvey E
HE
D000818:Animals; D003126:Colostrum / Q000737:chemistry*; D019587:Dietary Supplements / Q000032:analysis*; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis* / Q000276:immunology; D008892:Milk / Q000737:chemistry*
D007074:Immunoglobulin G