[Predictive factors of failure extubation among preterm infants].
OBJECTIVE
To determine the factors that lead to extubation failure among preterm newborns (PTN).


METHODS
Failure was determined when patients had to be reintubated during the first 72 hours. Critically-ill preterm newborns needing mechanical assisted ventilation at least during 24 hours were studied prospectively. Two groups were included: Group A, who failed in extubation for the first time and Group B, a control group who did not fail. Significance was set a p <0.05.


RESULTS
Gestational age and birth weight showed significant differences in Group B (control group). Significant factors in the multivariate analysis were gestational age < 32 weeks, caloric intake < or = 100 calories/kg/day and mean airway pressure (MAP) > or = [corrected] 4.5 cm H2O.


CONCLUSIONS
According to our results, an extubation should be planned whenever a patient is a PTN, has a gestational age of <32 weeks, a caloric intake >100 cal/kg/day, and its ventilator MAP is <4.5 cm H2O.
Tapia-Rombo
Carlos Antonio
CA
Servicio de Neonatología de la Unidad Médica de Alta Especialidad Hospital General Dr. Gaudencio González Garza, Centro Médico Nacional La Raza, Instituto Mexicano del Seguro Social, México, D.F., México. tapiachar@yahoo.com.mx
Galindo-Alvarado
Angel Melquíades
AM
Saucedo-Zavala
Víctor Joel
VJ
Cuevas-Urióstegui
Maria Luisa
ML
D001724:Birth Weight; D016022:Case-Control Studies; D016638:Critical Illness / Q000628:therapy; D005260:Female; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D008297:Male; D015999:Multivariate Analysis; D011446:Prospective Studies; D012121:Respiration, Artificial; D019233:Retreatment