title: Giant gastrointestinal stromal tumor of the stomach in an elderly patient.
abstract: We report a case of giant gastrointestinal stromal tumor (GIST) of the stomach of 17 cm in diameter detected in an 88-year-old Caucasian female. An en-block resection of the mass requiring gastric and transverse colon resection was carried out. Pathological examination evidenced a smooth multicystic giant gastric GIST measuring 17 x 13 x 9 and weighing 1,630 g. At immunohistochemistry, the specimen was c-kit positive, CD34-positive, SMA-negative S100-negative, desmin-negative, CD31-negative, HMB45-negative, and calponin-negative. It was diagnosed as an uncommitted GIST at high risk for malignancy.
authors.affiliation: Department of General Surgery, ASO S. Croce e Carle, Cuneo, Italy.
authors.forename: Herbert Maria
authors.initials: HM
authors.lastname: Dal Corso
authors.forename: Mario
authors.initials: M
authors.lastname: Solej
authors.forename: Mario
authors.initials: M
authors.lastname: Nano
mesh_terms: D000369:Aged, 80 and over; D018952:Antigens, CD34; D005260:Female; D046152:Gastrointestinal Stromal Tumors / Q000098:blood supply / Q000175:diagnosis* / Q000601:surgery; D006801:Humans; D007150:Immunohistochemistry; D019009:Proto-Oncogene Proteins c-kit; D013274:Stomach Neoplasms / Q000098:blood supply / Q000175:diagnosis* / Q000601:surgery
chemical_list: D018952:Antigens, CD34; D019009:Proto-Oncogene Proteins c-kit