Cerebral palsy due to nonlethal maternal carbon monoxide intoxication.
BACKGROUND
Carbon monoxide (CO) poisoning in pregnancy is a relatively rare occurrence, but it can result in fetal mortality and neurologic complications in fetuses who survive to term.


METHODS
We describe the course of an infant who was acutely exposed to CO at 20 weeks of gestation.


CONCLUSIONS
We conclude that despite maternal well-being, CO intoxication at critical periods of human brain development can lead to hypoxic-ischemic lesions in the globus pallidus and that dystonic cerebral palsy may develop in the infant during long-term follow-up.
Alehan
Füsun
F
Department of Pediatrics, Neurology Division, Baskent University Faculty of Medicine, Ankara, Turkey.
Erol
Ilknur
I
Onay
Ozge Sürmeli
OS
D000014:Abnormalities, Drug-Induced / Q000209:etiology*; D000328:Adult; D001921:Brain / Q000473:pathology; D002248:Carbon Monoxide / Q000009:adverse effects*; D002249:Carbon Monoxide Poisoning; D002547:Cerebral Palsy / Q000139:chemically induced* / Q000473:pathology; D005260:Female; D047109:Fetal Development / Q000187:drug effects*; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D019570:Inhalation Exposure; D008279:Magnetic Resonance Imaging; D008297:Male; D018811:Maternal Exposure; D008431:Maternal-Fetal Exchange; D011247:Pregnancy
D002248:Carbon Monoxide