title: Tagged phosphine reagents to assist reaction work-up by phase-switched scavenging using a modular flow reactor.
abstract: The use of three orthogonally tagged phosphine reagents to assist chemical work-up via phase-switch scavenging in conjunction with a modular flow reactor is described. These techniques (acidic, basic and Click chemistry) are used to prepare various amides and tri-substituted guanidines from in situ generated iminophosphoranes.
authors.affiliation: Innovative Technology Centre (ACS), Department of Chemistry, Lensfield Road, Cambridge, UKCB2 1EW.
authors.forename: Christopher D
authors.initials: CD
authors.lastname: Smith
authors.forename: Ian R
authors.initials: IR
authors.lastname: Baxendale
authors.forename: Geoffrey K
authors.initials: GK
authors.lastname: Tranmer
authors.forename: Marcus
authors.initials: M
authors.lastname: Baumann
authors.forename: Stephen C
authors.initials: SC
authors.lastname: Smith
authors.forename: Russell A
authors.initials: RA
authors.lastname: Lewthwaite
authors.forename: Steven V
authors.initials: SV
authors.lastname: Ley