title: [Comparative analisys of localization NR1 and NR2 subunits of NMDA-receptor in the brain structures in honeybee (Apis mellifera L.) and Drosophila (Drosophila melanogaster, wild type canton-S)].
abstract: Localization NR1 and NR2 subunits of NMDA-receptor was studied in brain structures of the honeybee and Drosophila by immunohistochemistry. The Western-blotting and NR1 subunit antisense-knockdown confirmed specificity of antibodies to NR1 and NR2 subunits. The data obtained demonstrated similar distribution of NR1 and NR2 subunits of NMDA-receptor in the insect brain (cranial ganglion). The brain regions with the highest expression NR1 and NR2 were different in the honeybee and Drosophila. This can be associated with behavioral repertoire peculiarities in these insects.
authors.forename: T G
authors.initials: TG
authors.lastname: Zachepilo
authors.forename: Iu F
authors.initials: IuF
authors.lastname: Il'inykh
authors.forename: N G
authors.initials: NG
authors.lastname: Lopatina
authors.forename: D A
authors.initials: DA
authors.lastname: Molotkov
authors.forename: A V
authors.initials: AV
authors.lastname: Popov
authors.forename: E V
authors.initials: EV
authors.lastname: Savateeva-Popova
authors.forename: A I
authors.initials: AI
authors.lastname: Vaĭdo
authors.forename: E G
authors.initials: EG
authors.lastname: Chesnokova
mesh_terms: D000818:Animals; D001516:Bees / Q000033:anatomy & histology / Q000737:chemistry*; D001921:Brain / Q000648:ultrastructure; D001923:Brain Chemistry; D004331:Drosophila melanogaster / Q000033:anatomy & histology / Q000737:chemistry*; D005260:Female; D007150:Immunohistochemistry; D008297:Male; D016372:RNA, Antisense / Q000494:pharmacology; D016194:Receptors, N-Methyl-D-Aspartate / Q000032:analysis* / Q000037:antagonists & inhibitors / Q000235:genetics
chemical_list: C409466:NR1 NMDA receptor; D016372:RNA, Antisense; D016194:Receptors, N-Methyl-D-Aspartate