Mucin (qniumucin), a glycoprotein from jellyfish, and determination of its main chain structure.
We extracted a novel glycoprotein, a member of the mucin family, from five species of jellyfish with high yields (1%-3% dry weight, 0.02%-0.1% wet weight) and determined its main chain structure and molecular mass. The glycoprotein contains unique tandem repeats of eight amino acids, of which two threonine residues are probably glycosylated by N-acetyl-d-galactosamine (GalNAc). We named this substance, which is common in jellyfish and similar to the human mucin MUC5AC, "qniumucin" and suggested the utilization of this compound as a new marine resource.
Masuda
Akiko
A
Riken (The Institute of Physical and Chemical Research), 2-1 Hirosawa, Wako, Saitama 351-0198, Japan.
Baba
Takayuki
T
Dohmae
Naoshi
N
Yamamura
Masahiro
M
Wada
Hiroo
H
Ushida
Kiminori
K
D000595:Amino Acid Sequence; D000818:Animals; D006801:Humans; D008386:Marine Biology; D055271:Mucin 5AC; D009077:Mucins / Q000737:chemistry / Q000302:isolation & purification*; D037401:Scyphozoa / Q000737:chemistry*
C524678:MUC5AC protein, human; D055271:Mucin 5AC; D009077:Mucins; C522139:qniumucin