Hand eczema is common and multifactorial.
Clinicians agree that hand eczema is multifactorial, although there are many uncertainties regarding causative factors. Atopic dermatitis is assumed to be a major risk factor, whereas the role of allergies is overestimated. Twin studies may shed light on the contribution of other endogenous, possibly genetic factors versus the role of exposure to environmental agents, with the latter being amenable to prevention and intervention.
Coenraads
Pieter-Jan
PJ
Dermatology Department, University Medical Centre Groningen, University of Groningen, Groningen, The Netherlands. p.j.coenraads@med.umcg.nl
D003876:Dermatitis, Atopic / Q000150:complications; D004485:Eczema / Q000453:epidemiology* / Q000209:etiology* / Q000235:genetics; D004781:Environmental Exposure / Q000009:adverse effects / Q000517:prevention & control; D020022:Genetic Predisposition to Disease; D006225:Hand / Q000473:pathology*; D006306:Health Surveys; D006801:Humans; D006967:Hypersensitivity / Q000150:complications; D015994:Incidence; D011788:Quality of Life; D012307:Risk Factors; D018433:Twin Studies as Topic