title: Human parvovirus 4 in the bone marrow of Italian patients with AIDS.
abstract: Human parvovirus 4 (PARV4) is a recently discovered member of the Parvoviridae. We investigated the presence of this virus in bone-marrow aspirates of 35 Italian patients with AIDS. Viral DNA was detected by polymerase chain reaction in over 40% of patients (16/35). The infection was most prevalent in injection drug users (IDU; 12/18; 66.7%) as opposed to non-IDU (4/17; 23.5%). PARV4 infection is widespread in Italian patients with AIDS.
authors.affiliation: Department of Infectious Diseases, Luigi Sacco Hospital, Milan, Italy.
authors.forename: Erika
authors.initials: E
authors.lastname: Longhi
authors.forename: Giovanna
authors.initials: G
authors.lastname: Bestetti
authors.forename: Veronica
authors.initials: V
authors.lastname: Acquaviva
authors.forename: Antonella
authors.initials: A
authors.lastname: Foschi
authors.forename: Roberta
authors.initials: R
authors.lastname: Piolini
authors.forename: Luca
authors.initials: L
authors.lastname: Meroni
authors.forename: Carlo
authors.initials: C
authors.lastname: Magni
authors.forename: Spinello
authors.initials: S
authors.lastname: Antinori
authors.forename: Carlo
authors.initials: C
authors.lastname: Parravicini
authors.forename: Mario
authors.initials: M
authors.lastname: Corbellino
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000821:virology*; D000328:Adult; D001853:Bone Marrow / Q000821:virology*; D004279:DNA, Viral / Q000032:analysis*; D005260:Female; D005838:Genotype; D015497:HIV-1; D016174:Hepacivirus / Q000235:genetics; D006526:Hepatitis C / Q000821:virology; D006801:Humans; D007558:Italy / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D010321:Parvoviridae / Q000235:genetics*; D010322:Parvoviridae Infections / Q000821:virology*; D015995:Prevalence; D015819:Substance Abuse, Intravenous / Q000821:virology; D019562:Viral Load
chemical_list: D004279:DNA, Viral