Spongian diterpenoids from the sponge Spongia (Heterofibria) sp.
Five new (1, 2, 4-6) and one known (3) diterpenoid were isolated from the keratose sponge Spongia (Heterofibria) sp. Structures of these compounds and their absolute configurations were proposed on the basis of X-ray analysis of 1, its CD spectrum, and NMR and MS spectroscopic studies of 1-6. One of the new diterpenoids was shown to be 2(R),3(S),4(S)-3,18-methylene-2-acetoxyspongia-13(16),14-diene (6), possessing a novel carbon skeleton system.
Ponomarenko
Ludmila P
LP
Pacific Institute of Bioorganic Chemistry, Far East Branch of the Russian Academy of Sciences, Prospect 100 let Vladivostoku, 159, Vladivostok 690022, Russian Federation.
Kalinovsky
Anatoly I
AI
Afiyatullov
Shamil Sh
SSh
Pushilin
Michail A
MA
Gerasimenko
Andrey V
AV
Krasokhin
Vladimir B
VB
Stonik
Valentin A
VA
D000818:Animals; D018360:Crystallography, X-Ray; D004224:Diterpenes / Q000737:chemistry* / Q000302:isolation & purification*; D008968:Molecular Conformation; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D011161:Porifera / Q000737:chemistry*
D004224:Diterpenes