Surface modification of resorcinarene based self-assembled solid lipid nanoparticles for drug targeting.
Prolyl-bearing amphiphilic resorcinarenes, e.g. tetrakis(N-methylprolyl)tetraundecylcalix[4]resorcinarene, self-assemble as stable solid lipid nanoparticles; these fully characterized systems could be further functionalized at their surface with proteins, and interact with specific antibodies bound on a sensor surface.
Ehrler
Stefan
S
University of Applied Sciences Northwestern Switzerland, School of Life Sciences, Institute of Chemistry and Bioanalytics, Gründenstrasse 40, 4132 Muttenz, Switzerland.
Pieles
Uwe
U
Wirth-Heller
Amina
A
Shahgaldian
Patrick
P
D047250:Calixarenes / Q000737:chemistry*; D016503:Drug Delivery Systems; D018625:Microscopy, Atomic Force; D008855:Microscopy, Electron, Scanning; D053758:Nanoparticles / Q000737:chemistry*; D010316:Particle Size; D010649:Phenylalanine / Q000031:analogs & derivatives* / Q000737:chemistry; D012710:Serum Albumin, Bovine / Q000737:chemistry
C466160:resorcinarene; D047250:Calixarenes; D012710:Serum Albumin, Bovine; D010649:Phenylalanine