title: [The effect of cyrstal water on determining content of baicalin].
abstract: OBJECTIVE
  To explore the effect of crystal water on deteriming content of baicalin.
  
  
  METHODS
  Baicalin samples containing different amount of crystal water were determined by HPLC.
  
  
  RESULTS
  The determining results of baicalin were accurate and stable on condition that the samples contain some crystal water or some impurities, and the determining results of baicalin were reduced remarkably on condition that the samples are anhydrous and pure.
  
  
  CONCLUSIONS
  The determining results of baicalin contents were accurate and stable only if the oxygen in 1 place forms hydrogen bond, and the determining results of baicalin contents were reduced remarkably on condition that the oxygen in 1 place forms protonated ether of form positive carbonic.
authors.affiliation: College of Pharmacy, Shandong University, Jinan 250012, China.
authors.forename: Hou-quan
authors.initials: HQ
authors.lastname: Wang
authors.forename: Gang
authors.initials: G
authors.lastname: Ni
authors.forename: Hui-xia
authors.initials: HX
authors.lastname: Ren
mesh_terms: D002851:Chromatography, High Pressure Liquid; D004365:Drugs, Chinese Herbal / Q000737:chemistry* / Q000592:standards; D005419:Flavonoids / Q000032:analysis* / Q000737:chemistry; D006860:Hydrogen Bonding; D015394:Molecular Structure; D010946:Plants, Medicinal / Q000737:chemistry*; D011786:Quality Control; D031364:Scutellaria baicalensis / Q000737:chemistry*; D014867:Water
chemical_list: D004365:Drugs, Chinese Herbal; D005419:Flavonoids; D014867:Water; C038044:baicalin