Membrane protein chaperones: a new twist in the tail?
The integration of tail-anchored membrane proteins at the endoplasmic reticulum occurs via a specialised ATP-dependent pathway, but the cytosolic factors involved have proven elusive. A novel ATPase that mediates this process has now been identified.
Rabu
Catherine
C
Faculty of Life Sciences, University of Manchester, Manchester M13 9PT, UK.
High
Stephen
S
D000251:Adenosine Triphosphatases / Q000378:metabolism; D000255:Adenosine Triphosphate / Q000378:metabolism*; D001692:Biological Transport; D003600:Cytosol / Q000378:metabolism; D004721:Endoplasmic Reticulum / Q000378:metabolism* / Q000648:ultrastructure; D015966:Gene Expression Regulation, Fungal; D008565:Membrane Proteins / Q000378:metabolism*; D011499:Protein Processing, Post-Translational; D012441:Saccharomyces cerevisiae / Q000235:genetics / Q000378:metabolism* / Q000648:ultrastructure; D029701:Saccharomyces cerevisiae Proteins / Q000235:genetics / Q000378:metabolism*; D015398:Signal Transduction
D008565:Membrane Proteins; D029701:Saccharomyces cerevisiae Proteins; D000255:Adenosine Triphosphate; D000251:Adenosine Triphosphatases