title: Seroreactivity to Pf 155/RESA in two malaria endemic ecological zones in Southern Ghana.
abstract: Seroepidemiological data are becoming important tools in determining transmission patterns of malaria. We have undertaken a study in 2 different ecological zones in southern Ghana during both the dry and wet seasons. Virtually all the subjects studied were positive to the crude parasite antigen (92%), with majority showing high titres in both areas. Whilst there was a statistical difference in Geometrical Mean Titre (GMT) between the two areas, seasonal variation was not seen. Antibody levels to the Pfl55/RESA and its repeat pepetide (EENV)6 increased progres notsively with age in endemic areas. These findings have relevance in determining malaria transmission in endemic areas.
authors.affiliation: 'Noguchi Memorial Institute for Medical Research, Box 25, Legon Ghana. Telephone: (233) 21 500374; Fax: (233) 21 502 182; Email: noguchi@ncs.com.gh.
authors.forename: B A
authors.initials: BA
authors.lastname: Gyan
authors.forename: E
authors.initials: E
authors.lastname: Afari
authors.forename: F
authors.initials: F
authors.lastname: Nkrumah
authors.forename: S
authors.initials: S
authors.lastname: Dunyoh
authors.forename: H
authors.initials: H
authors.lastname: Perlmann