A new nonadride derivative from mangrove fungus (strain No. k38).
A new nonadride derivative, ( - )-1-hydroxybyssochlamic acid (1) and the known ( - )-byssochlamic acid (2) were isolated from mangrove fungus (strain No. k38) collected from the South China Sea coast. The structure and relative configuration of 1 were elucidated by spectral data and X-ray diffraction analysis. Primary bioassays showed that 2 had medium cytotoxic activity against HEp-2 and HepG2 Cells, and 1 exhibited weak activity.
Li
C-Y
CY
School of Chemistry and Chemical Engineering, Zhongshan University, 510275 Guangzhou, China.
Yang
R-Y
RY
Lin
Y-C
YC
She
Z-G
ZG
Zhou
S-N
SN
D000970:Antineoplastic Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D045744:Cell Line, Tumor; D005658:Fungi / Q000737:chemistry*; D005663:Furans / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D006575:Heterocyclic Compounds, 3-Ring / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D008299:Maleic Anhydrides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D014961:X-Ray Diffraction
C525296:1-hydroxybyssochlamic acid; D000970:Antineoplastic Agents; D005663:Furans; D006575:Heterocyclic Compounds, 3-Ring; D008299:Maleic Anhydrides; C010875:byssochlamic acid