Bone formation in elastase-induced rabbit aneurysms embolized with platinum coils: report of 2 cases.
Histologic findings in 71 elastase-induced rabbit aneurysms embolized with platinum coils were retrospectively reviewed. Mature bone formation was found in 2 aneurysms, one with coils implanted for 3 months and the other with coils implanted for 1 year. We present the histologic findings and offer potential explanations for these observations. These findings may be relevant in understanding mechanisms of aneurysm healing after coil embolization.
Dai
D
D
Neuroradiology Research Laboratory, Department of Radiology, Mayo Clinic, Rochester, MN 55905, USA.
Ding
Y H
YH
Kadirvel
R
R
Lewis
D A
DA
Cloft
H J
HJ
Kallmes
D F
DF
D000818:Animals; D001842:Bone and Bones / Q000473:pathology*; D002828:Choristoma / Q000175:diagnosis / Q000209:etiology*; D004621:Embolization, Therapeutic / Q000009:adverse effects* / Q000379:methods; D002532:Intracranial Aneurysm / Q000139:chemically induced* / Q000150:complications / Q000628:therapy*; D008679:Metaplasia / Q000175:diagnosis / Q000209:etiology; D010196:Pancreatic Elastase; D011817:Rabbits
D010196:Pancreatic Elastase