title: Recurrent neonatal group B streptococcal disease associated with infected breast milk.
abstract: Group B streptococcus (GBS) is a major cause of severe systemic infections among the newborn. Both recurrent and maternal mastitis-associated, group B streptococcus diseases are uncommon. Persistence of GBS colonization of infants' mucous membrane is postulated to influence the pathogeneses of recurrent GBS infection. The authors describe a term infant who was treated for GBS sepsis and meningitis and then later developed recurrent GBS sepsis, without meningitis, due to feeding of infected breast milk. Randomly amplified polymorphic DNA polymerase chain reaction assay was performed to demonstrate that the GBS isolates from the first and second episode of infection and the maternal milk are identical. The authors conclude that transmission of GBS through breast milk should be considered in cases of recurrent neonatal GBS infection and bacterial culture of breast milk should be routinely performed in such cases.
authors.affiliation: Department of Pediatrics, Chi-Mei Foundation Medical Center, Tainan, Taiwan.
authors.forename: Lin-Yu
authors.initials: LY
authors.lastname: Wang
authors.forename: Chun-Ta
authors.initials: CT
authors.lastname: Chen
authors.forename: Won-Hsiung
authors.initials: WH
authors.lastname: Liu
authors.forename: Yin-Hsuan
authors.initials: YH
authors.lastname: Wang
mesh_terms: D000667:Ampicillin / Q000627:therapeutic use; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001942:Breast Feeding; D002675:Child, Preschool; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D018445:Infectious Disease Transmission, Vertical; D008895:Milk, Human / Q000382:microbiology; D016133:Polymerase Chain Reaction; D012008:Recurrence; D013290:Streptococcal Infections / Q000188:drug therapy / Q000635:transmission*; D013292:Streptococcus agalactiae
chemical_list: D000900:Anti-Bacterial Agents; D000667:Ampicillin