A facile Er(OTf)3-catalyzed synthesis of 2,3-unsaturated O- and S-glycosides.
Er(OTf)(3) is a useful catalyst for the Ferrier rearrangement furnishing high yields of O- and S-glycosides. The transformation has wide applicability, cleaner reaction profiles, mild reaction conditions, and high stereoselectivity and the catalyst, which is also commercially available, can be recovered and reused.
Procopio
Antonio
A
Dipartimento Farmacobioiologiche, Università degli Studi della Magna Graecia Complesso Ninì Barbieri, 88021, Roccelletta di Borgia (CZ), Italy. procopio@unicz.it
Dalpozzo
Renato
R
De Nino
Antonio
A
Maiuolo
Loredana
L
Nardi
Monica
M
Oliverio
Manuela
M
Russo
Beatrice
B
D002384:Catalysis; D006027:Glycosides / Q000138:chemical synthesis*; D013865:Thioglycosides / Q000138:chemical synthesis
D006027:Glycosides; D013865:Thioglycosides