title: Spongian diterpenoids from the sponge Spongia (Heterofibria) sp.
abstract: Five new (1, 2, 4-6) and one known (3) diterpenoid were isolated from the keratose sponge Spongia (Heterofibria) sp. Structures of these compounds and their absolute configurations were proposed on the basis of X-ray analysis of 1, its CD spectrum, and NMR and MS spectroscopic studies of 1-6. One of the new diterpenoids was shown to be 2(R),3(S),4(S)-3,18-methylene-2-acetoxyspongia-13(16),14-diene (6), possessing a novel carbon skeleton system.
authors.affiliation: Pacific Institute of Bioorganic Chemistry, Far East Branch of the Russian Academy of Sciences, Prospect 100 let Vladivostoku, 159, Vladivostok 690022, Russian Federation.
authors.forename: Ludmila P
authors.initials: LP
authors.lastname: Ponomarenko
authors.forename: Anatoly I
authors.initials: AI
authors.lastname: Kalinovsky
authors.forename: Shamil Sh
authors.initials: SSh
authors.lastname: Afiyatullov
authors.forename: Michail A
authors.initials: MA
authors.lastname: Pushilin
authors.forename: Andrey V
authors.initials: AV
authors.lastname: Gerasimenko
authors.forename: Vladimir B
authors.initials: VB
authors.lastname: Krasokhin
authors.forename: Valentin A
authors.initials: VA
authors.lastname: Stonik
mesh_terms: D000818:Animals; D018360:Crystallography, X-Ray; D004224:Diterpenes / Q000737:chemistry* / Q000302:isolation & purification*; D008968:Molecular Conformation; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D011161:Porifera / Q000737:chemistry*
chemical_list: D004224:Diterpenes