title: Quality of life, sexual function and decisional regret at 1 year after surgical treatment for localized prostate cancer.
abstract: OBJECTIVE
  To examine the effect of changes in quality of life (QoL) and levels of sexual function on decisional regret after surgical treatment of localized prostate cancer.
  
  
  METHODS
  Patients who decided to have a radical prostatectomy (RP) were assessed for health-related QoL using the general European Organization for Research and Treatment of Cancer C30 instrument and disease-specific prostate cancer module, and sexual function using the abbreviated International Index of Erectile Function-5 before and 1 year after RP. Decision control was measured before RP, and decisional regret 1 year afterward, using measures mailed to participants 1 year after treatment.
  
  
  RESULTS
  Of 130 respondents (mean age 62 years), 4% expressed regret over their decision to have surgery. Physical and social functioning, and finances, were compromised, while emotional functioning and treatment-related symptoms improved by 1 year. Higher levels of decisional regret were correlated with decreases in role and social functioning, increased pain and financial difficulty (all P < 0.01). Sexual function was decreased (P < 0.001) after treatment. Men reported feeling less masculine, having less sexual enjoyment, difficulty in getting and maintaining an erection, and discomfort when being sexually intimate after surgery. Mean scores of decisional regret were similar among patients who reported assuming either active (84%) or collaborative (11%) roles in treatment decision-making. Men who assumed a passive role reported the most variability and highest scores on decision regret.
  
  
  CONCLUSIONS
  Few men regretted having RP at 1 year after treatment, even though some QoL functions and domains were significantly affected. Ongoing assessment of the effect of surgical treatment on sexual function, sexuality and masculinity certainly deserves further exploration with this group of cancer survivors.
authors.affiliation: Department of Urologic Sciences, University of British Columbia, Vancouver, BC, Canada.
authors.forename: B Joyce
authors.initials: BJ
authors.lastname: Davison
authors.forename: Alan I
authors.initials: AI
authors.lastname: So
authors.forename: S Larry
authors.initials: SL
authors.lastname: Goldenberg
mesh_terms: D000368:Aged; D002755:Choice Behavior; D003657:Decision Making; D007172:Erectile Dysfunction / Q000209:etiology / Q000523:psychology; D006801:Humans; D008297:Male; D008875:Middle Aged; D010358:Patient Participation / Q000523:psychology; D011468:Prostatectomy / Q000009:adverse effects / Q000523:psychology*; D011471:Prostatic Neoplasms / Q000523:psychology / Q000601:surgery*; D011788:Quality of Life; D011795:Surveys and Questionnaires