Use of Artemisinin (Qinghaosu) derivatives in the treatment of malaria.
Derivatives of the Chinese herbal remedy ginghaosu (artemisinin) are useful in the treatment of multiple-drug resistant malaria. This review covers the discovery, development, clinical pharmacology and toxicology of these compounds, with emphasis on those derivatives currently in use in parts of Africa.
Kokwaro
G O
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Department of Pharmaceutics & Pharmacy Practice, Faculty of Pharmacy, College of Health Sciences, University of Nairobi, P.O. Box 19676, Nairobi, Kenya.