title: Synthesis and antiviral evaluation of AZT analogues with A spacer arm between glucidic and base moieties. Part II.
abstract: This article describes the synthesis of a series of AZT analogues bearing an acyclic chain between the sugar and the base moieties is described. These new compounds were readily obtained using microwave irradiation. The compounds were characterized by (1)H NMR and IR spectroscopy. Antiviral (HIV-1) properties of these compounds were examined.
authors.affiliation: Université de Limoges, Laboratoire de Chimie des Substances Naturelles, Faculté des Sciences et Techniques, Limoges, France.
authors.forename: Vincent
authors.initials: V
authors.lastname: Roy
authors.forename: Rachida
authors.initials: R
authors.lastname: Zerrouki
authors.forename: Pierre
authors.initials: P
authors.lastname: Krausz
authors.forename: Géraldine
authors.initials: G
authors.lastname: Laumond
authors.forename: Anne Marie
authors.initials: AM
authors.lastname: Aubertin
mesh_terms: D000998:Antiviral Agents / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D002461:Cell Line, Transformed; D002470:Cell Survival / Q000187:drug effects; D015497:HIV-1 / Q000187:drug effects; D006801:Humans; D008956:Models, Chemical; D015394:Molecular Structure; D009705:Nucleosides / Q000737:chemistry*; D015215:Zidovudine / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology
chemical_list: D000998:Antiviral Agents; D009705:Nucleosides; D015215:Zidovudine