title: Method to perform IV injections on mice using the facial vein.
abstract: A novel technique for gaining IV access in a mouse model is presented. Using a cut-down approach, the facial vein is identified through an incision from anterior to the external auditory meatus to posterior to the lateral ispilateral canthus. A small gage needle (30gauge) may be inserted to inject medications. A high success rate (93%) as determined by direct visualization is achieved. The technique would prove especially useful for animals slated for kinematic testing as the incision does not interfere with the animal's ventral surface.
authors.affiliation: Department of Neurosurgery, Temple University School of Medicine, United States.
authors.forename: H B
authors.initials: HB
authors.lastname: Levene
authors.forename: M
authors.initials: M
authors.lastname: Zhang
authors.forename: C J
authors.initials: CJ
authors.lastname: Erb
authors.forename: J I
authors.initials: JI
authors.lastname: Jallo
authors.forename: C M
authors.initials: CM
authors.lastname: Loftus
authors.forename: R F
authors.initials: RF
authors.lastname: Tuma
mesh_terms: D000818:Animals; D005145:Face; D005260:Female; D007839:Functional Laterality; D007275:Injections, Intravenous / Q000379:methods*; D051379:Mice; D008810:Mice, Inbred C57BL; D014680:Veins / Q000502:physiology*