Distant skeletal muscle metastasis from intrahepatic cholangiocarcinoma presenting as Budd-Chiari syndrome.
Intrahepatic cholangiocarcinoma is a malignant neoplasm arising from the biliary epithelium, which frequently invades adjacent organs or metastasizes to other visceral organs such as the lungs, bones, adrenals, and brain. However, distant skeletal muscle metastasis of cholangiocarcinoma has never been described before to the best of our knowledge and, furthermore, Budd-Chiari syndrome secondary to intrahepatic cholangiocarcinoma is also extremely rare. Here we present the first case overall of distant muscle metastasis from intrahepatic cholangiocarcinoma presenting as Budd-Chiari syndrome. A 44-year-old man admitted to the hospital with complaints of abdominal distension, edema of both legs, back pain and anorexia of 30 d' duration. Computed tomography and ultrasonography-guided percutaneous muscle biopsy established intrahepatic cholangiocarcinoma with disseminated thrombosis from inferior vena cava to bilateral iliac and femoral veins, and multiple skeletal muscle metastases in bilateral buttock and erector spinal muscle.
Kwon
Oh-Sung
OS
Department of Internal Medicine, Eulji University Hospital, Seoul, Korea.
Jun
Dae-Won
DW
Kim
Sang-Heum
SH
Chung
Mee-Yeon
MY
Kim
Nam-In
NI
Song
Moon-Hee
MH
Lee
Han-Hyo
HH
Kim
Seung-Hwan
SH
Jo
Yoon-Ju
YJ
Park
Young-Sook
YS
Joo
Jong-Eun
JE
D000328:Adult; D001650:Bile Duct Neoplasms / Q000473:pathology*; D001653:Bile Ducts, Intrahepatic; D001706:Biopsy; D006502:Budd-Chiari Syndrome / Q000175:diagnosis* / Q000473:pathology; D018281:Cholangiocarcinoma / Q000175:diagnosis* / Q000556:secondary*; D003937:Diagnosis, Differential; D005268:Femoral Vein / Q000473:pathology; D006801:Humans; D007084:Iliac Vein / Q000473:pathology; D008297:Male; D019042:Muscle Neoplasms / Q000175:diagnosis* / Q000556:secondary*; D018482:Muscle, Skeletal / Q000473:pathology; D013927:Thrombosis / Q000473:pathology