title: Serotypes, antimicrobial susceptibility, and gyr A gene mutation of Campylobacter jejuni isolates from humans and chickens in Thailand.
abstract: In Thailand, 51% (36/70) Campylobacter jejuni isolates from humans and 68% (47/69) isolates from poultry were classified into 10 Penner serotypes (serotype B, C, R, E, G, A, K, D, I, and L) and 9 serotypes (serotype A, C, I, K, B, E, S, D, and L), respectively. The rate of antimicrobial drug resistance to nalidixic acid, ciprofloxacin, ampicillin, tetracycline, and erythromycin shown by human isolates were 96%, 96%, 29%, 57%, and 14%, while that shown by poultry isolates were 77%, 77%, 22%, 26%, and 17%, respectively. All quinolone-resistant strains contained a mutation in the gyrA gene (T(86)-->I(86)), suggesting that the strains were already widespread in Thailand.
authors.affiliation: Faculty of Veterinary Medicine, Kasetsart University, Bangkok 10900, Thailand.
authors.forename: Sumalee
authors.initials: S
authors.lastname: Boonmar
authors.forename: Yukio
authors.initials: Y
authors.lastname: Morita
authors.forename: Masahiro
authors.initials: M
authors.lastname: Fujita
authors.forename: Leelaowadee
authors.initials: L
authors.lastname: Sangsuk
authors.forename: Karun
authors.initials: K
authors.lastname: Suthivarakom
authors.forename: Pawin
authors.initials: P
authors.lastname: Padungtod
authors.forename: Soichi
authors.initials: S
authors.lastname: Maruyama
authors.forename: Hidenori
authors.initials: H
authors.lastname: Kabeya
authors.forename: Masahiko
authors.initials: M
authors.lastname: Kato
authors.forename: Kunihisa
authors.initials: K
authors.lastname: Kozawa
authors.forename: Shigeki
authors.initials: S
authors.lastname: Yamamoto
authors.forename: Hirokazu
authors.initials: H
authors.lastname: Kimura
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D002169:Campylobacter Infections / Q000382:microbiology*; D016123:Campylobacter jejuni / Q000187:drug effects* / Q000201:enzymology / Q000235:genetics* / Q000302:isolation & purification; D002645:Chickens / Q000382:microbiology*; D027081:DNA Gyrase / Q000235:genetics*; D004271:DNA, Fungal / Q000235:genetics; D024881:Drug Resistance, Bacterial; D006801:Humans; D008826:Microbial Sensitivity Tests; D017354:Point Mutation; D016133:Polymerase Chain Reaction; D011201:Poultry Diseases / Q000382:microbiology*; D012703:Serotyping; D013785:Thailand
chemical_list: D000900:Anti-Bacterial Agents; D004271:DNA, Fungal; D027081:DNA Gyrase