title: Wildlife ecological screening levels for inhalation of volatile organic chemicals.
abstract: For most chemicals, evaluation of ecological risk typically does not address inhalation because ingestion dominates exposure. However, burrowing ecological receptors have an increased exposure potential from inhalation at sites contaminated with volatile chemicals in the subsurface. Evaluation of ecological risk from contaminants like volatile organic chemicals (VOCs) is constrained by a lack of relevant ecological screening levels (ESLs). To address this need, inhalation ESLs were developed for 16 VOCs: Acetone, benzene, carbon tetrachloride, chloroform, chloromethane, dichlorodifluoromethane, 1,1-dichloroethane, 1,2-dichloroethane, 1,1-dichloroethene, methylene chloride, tetrachloroethene, toluene, 1,1,1-trichloroethane, trichloroethene, trichlorofluoromethane, and total xylene. These ESLs are based on Botta's pocket gopher (Thomomys bottae) as a representative fossorial receptor. The ESLs are presented with an emphasis on the process for developing inhalation toxicity reference values to illustrate the selection of suitable toxicity data and effect levels from the literature. The resulting ESLs provide a quantitative method for evaluating ecological risk of VOCs through comparison to relevant exposure data such as direct burrow-air measurements. The toxicity reference value development and ESL calculation processes and assumptions detailed here are provided as bases from which risk assessors can use or refine to suit site-specific needs with respect to toxicity and exposure inputs.
authors.affiliation: Neptune and Company, 1505 15th Street, Suite B, Los Alamos, New Mexico 87544, USA. patricia@neptuneinc.org
authors.forename: Patricia
authors.initials: P
authors.lastname: Gallegos
authors.forename: Jill
authors.initials: J
authors.lastname: Lutz
authors.forename: James
authors.initials: J
authors.lastname: Markwiese
authors.forename: Randall
authors.initials: R
authors.lastname: Ryti
authors.forename: Rich
authors.initials: R
authors.lastname: Mirenda
mesh_terms: D000818:Animals; D000835:Animals, Wild; D004463:Ecology; D046348:Gophers; D019570:Inhalation Exposure; D009930:Organic Chemicals / Q000008:administration & dosage / Q000633:toxicity*; D018570:Risk Assessment; D014835:Volatilization
chemical_list: D009930:Organic Chemicals