title: A case report of dengue virus infection and acalculous cholecystitis in a pregnant returning traveler.
abstract: Dengue viral infections present a significant risk during pregnancy to both mother and fetus. A young woman at 13 weeks' gestation presented with fever and abdominal pain following a diarrheal illness after returning from Puerto Rico. Over the course of 5 days, she developed nausea, petechiae, severe thrombocytopenia, and acalculous cholecystitis. After a serologic diagnosis of acute infection with dengue virus, she was provided supportive care. An uncomplicated pregnancy led to delivery of a healthy infant at 40 weeks gestation. Travel during pregnancy to dengue-endemic areas poses a risk to both mother and fetus. Pregnancies complicated by dengue infection require close monitoring for potential maternal and fetal complications.
authors.affiliation: Department of Medicine, Division of Allergy and Infectious Disease, University of Washington, Seattle, WA 98195, USA. berring@u.washington.edu
authors.forename: William R
authors.initials: WR
authors.lastname: Berrington
authors.forename: Jane
authors.initials: J
authors.lastname: Hitti
authors.forename: Corey
authors.initials: C
authors.lastname: Casper
mesh_terms: D042101:Acalculous Cholecystitis / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D000328:Adult; D003715:Dengue / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D011247:Pregnancy; D011248:Pregnancy Complications / Q000175:diagnosis* / Q000473:pathology; D011251:Pregnancy Complications, Infectious / Q000175:diagnosis / Q000473:pathology; D011261:Pregnancy Trimester, First; D011295:Prenatal Care; D011296:Prenatal Diagnosis; D014195:Travel