C-C bond-forming reactions via Pd-mediated decarboxylative alpha-imino anion generation.
Alpha-imino anions are generated under neutral reaction conditions via a Pd-mediated decarboxylation of allyl diphenylglycinate imines with concomitant formation of a pi-allylpalladium species. The resulting delocalized anion can attack the pi-allyl-Pd(II) species or be intercepted by aldehydes to afford homoallylic amines or protected 1,2-amino alcohols, respectively.
Yeagley
Andrew A
AA
Department of Chemistry, University of Virginia, Charlottesville, Virginia 22904-4319, USA.
Chruma
Jason J
JJ