title: Uterine fibroid embolization: the utility of aortography in detecting ovarian artery collateral supply.
abstract: OBJECTIVE
  To retrospectively determine the sensitivity of ovarian artery (OA) visualization at aortography performed after uterine fibroid embolization (UFE) and, using OA arteriography as the reference standard, compare the extent of arterial flow to the uterus at aortography with selective ovarian arteriography, to establish the utility of aortography and ovarian arteriography in the routine practice of UFE.
  
  
  METHODS
  This study received institutional review board approval with waiver of informed consent and was HIPAA compliant. Retrospective review of 1129 consecutive UFE patients (1072 with aortograms, 57 excluded; mean age, 44 years; range, 21-60 years) was performed to identify all visible OAs. Visible OAs were independently graded by two interventional radiologists according to extent of pelvic arterial flow. If selective arteriography was performed, a second grade was assigned based on assessment of the selective study. Descriptive and summary statistics were used for assessment by the senior observer, and interobserver variability was determined.
  
  
  RESULTS
  Of 1072 UFE patients, 184 (17.2%) had at least one visible OA. Ten (0.8%) patients were identified at aortography with collateral OA supply to more than 10% of the uterus. In total, 251 OAs were visualized, and 157 of these were further evaluated with selective study. Sixty-two (5.8%) patients were identified at selective arteriography as having collateral OA supply. The sensitivity of aortography was approximately 18%. Interobserver concordance was high (kappa values of 0.81 and 0.90 for aortography and selective study, respectively), but not perfect.
  
  
  CONCLUSIONS
  Aortography rarely helps identify patients with substantial residual OA supply to the uterus and is a poor predictor of the extent of that supply, and thus may be of limited utility in routine UFE.
authors.affiliation: Department of Radiology, Georgetown University Hospital, 3800 Reservoir Rd NW, CG 201, Washington, DC 20007-2113, USA.
authors.forename: Amy M
authors.initials: AM
authors.lastname: White
authors.forename: Filip
authors.initials: F
authors.lastname: Banovac
authors.forename: Shadi
authors.initials: S
authors.lastname: Yousefi
authors.forename: Rebecca S
authors.initials: RS
authors.lastname: Slack
authors.forename: James B
authors.initials: JB
authors.lastname: Spies
mesh_terms: D000328:Adult; D001027:Aortography / Q000379:methods*; D001783:Blood Flow Velocity; D003097:Collateral Circulation; D004621:Embolization, Therapeutic / Q000379:methods*; D005260:Female; D006801:Humans; D007889:Leiomyoma / Q000098:blood supply* / Q000000981:diagnostic imaging* / Q000628:therapy*; D008875:Middle Aged; D010053:Ovary / Q000098:blood supply* / Q000000981:diagnostic imaging*; D011857:Radiographic Image Interpretation, Computer-Assisted; D019233:Retreatment; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D014594:Uterine Neoplasms / Q000000981:diagnostic imaging* / Q000628:therapy*