title: Economic burden of expected epidemiological changes in diseases related to tobacco, Mexico.
abstract: OBJECTIVE
  To determine health care costs and economic burden of epidemiological changes in diseases related to tobacco consumption.
  
  
  METHODS
  A time-series analysis in Mexico (1994-2005) was carried out on seven health interventions: chronic obstructive pulmonary diseases, lung cancer with and without surgical intervention, asthma in smokers and non-smokers, full treatment course with nicotine gum, and full treatment course with nicotine patch. According with Box-Jenkins methodology, probabilistic models were developed to forecast the expected changes in the epidemiologic profile and the expected changes in health care services required for selected interventions. Health care costs were estimated following the instrumentation methods and validated with consensus technique.
  
  
  RESULTS
  A comparison of the economic impact in 2006 vs. 2008 showed 20-90% increase in expected cases depending on the disease (p<0.05), and 25-93% increase in financial requirements (p<0.01). The study data suggest that changes in the demand for health services for patients with respiratory diseases related to tobacco consumption will continue showing an increasing trend.
  
  
  CONCLUSIONS
  In economic terms, the growing number of cases expected during the study period indicates a process of internal competition and adds an element of intrinsic competition in the management of preventive and curative interventions. The study results support the assumption that if preventive programs remain unchanged, the increasing demands for curative health care may cause great financial and management challenges to the health care system of middle-income countries like Mexico.
authors.affiliation: Health Services Unit, Research Center on Health Systems, Cuernavaca, Mexico. aarredon@insp.mx
authors.forename: Armando
authors.initials: A
authors.lastname: Arredondo
authors.forename: Carlos
authors.initials: C
authors.lastname: Carrillo
authors.forename: Alexis
authors.initials: A
authors.lastname: Zuñiga
mesh_terms: D001249:Asthma / Q000191:economics* / Q000453:epidemiology / Q000209:etiology; D017048:Health Care Costs / Q000706:statistics & numerical data*; D005102:Health Expenditures / Q000706:statistics & numerical data*; D006801:Humans; D008175:Lung Neoplasms / Q000191:economics* / Q000453:epidemiology / Q000209:etiology; D008800:Mexico / Q000453:epidemiology; D029424:Pulmonary Disease, Chronic Obstructive / Q000191:economics* / Q000453:epidemiology / Q000209:etiology; D014029:Tobacco Use Disorder / Q000150:complications / Q000191:economics* / Q000453:epidemiology