Continuous monitoring of ScvO(2) by a new fibre-optic technology compared with blood gas oximetry in critically ill patients: a multicentre study.
OBJECTIVE
The aim of this study was to compare the accuracy of the CeVOX monitor measuring continuous central venous saturation (ScvO(2)) with laboratory blood gas oximetry under clinical circumstances.


METHODS
Prospective, multicentre, observational study.


METHODS
Five adult general intensive care units.


METHODS
Fifty-three critically ill patients.


METHODS
The fibre-optic probe was inserted into an ordinary central venous catheter's distal lumen. Blood samples were taken from this line via a Y-adapter every 8 h and ScvO(2) was measured with a laboratory co-oximeter. Patients were observed for a maximum of 5 days. Results were compared using linear regression and the Bland and Altman plots.


RESULTS
The 526 matched pairs of ScvO(2) showed a significant correlation between the two methods (r = 0.79, p< 0.001). Bland-Altman plots showed an overall mean bias of -0.3% and moderate agreement (lower and upper levels of agreement: -13.2% and 12.5%). Correlation for the first time point, and for differences between the first two time points for each method revealed good correlation: (n = 53): r = 0.79, p< 0.001; (n = 50): r = 0.58, p< 0.001, respectively.


CONCLUSIONS
These results in a heterogeneous group of critically ill patients show that continuous ScvO(2) monitoring by the CeVOX technology yielded results comparable with those obtained by laboratory co-oximetry and therefore can be relied on in everyday clinical practice.
Molnar
Zsolt
Z
Department of Anaesthesia and Intensive Therapy, University of Pécs, 13 Ifjusag St., 7624, Pécs, Hungary. zsoltmolna@gmail.com
Umgelter
Andreas
A
Toth
Ildiko
I
Livingstone
David
D
Weyland
Andreas
A
Sakka
Samir G
SG
Meier-Hellmann
Andreas
A
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001784:Blood Gas Analysis / Q000295:instrumentation / Q000379:methods*; D003422:Critical Care / Q000379:methods*; D016638:Critical Illness; D005260:Female; D005336:Fiber Optic Technology; D006801:Humans; D008297:Male; D008875:Middle Aged; D008991:Monitoring, Physiologic / Q000295:instrumentation / Q000379:methods; D010092:Oximetry; D010100:Oxygen / Q000097:blood*
D010100:Oxygen