title: Variation in resistance to benzimidizole in different biocontrol agents based on protein sequence homology.
abstract: Benzimidazole resistance in thirty isolates of the biocontrol agents was studied with reference to specific mutations in the beta-tubulin genes. Our results suggest that apart from the correlation between specific mutations in the beta-tubulin gene and variation in resistance, the overall ratio of polar and non-polar amino-acids may also play a vital role in conferring benzimidazole resistance to these fungi.
authors.affiliation: BRD School of Biosciences, Sardar Patel University, Vallabh Vidyanagar- 388120, Gujarat, India. bjarullah@yahoo.com
authors.forename: B M S
authors.initials: BM
authors.lastname: Jarullah
authors.forename: R B
authors.initials: RB
authors.lastname: Subramanian
authors.forename: M J
authors.initials: MJ
authors.lastname: Jummanah
mesh_terms: D001203:Ascomycota / Q000187:drug effects / Q000235:genetics; D052982:Beauveria / Q000187:drug effects / Q000235:genetics; D001562:Benzimidazoles / Q000494:pharmacology*; D002219:Carbamates / Q000494:pharmacology; D025141:Drug Resistance, Fungal / Q000235:genetics; D010143:Paecilomyces / Q000187:drug effects / Q000235:genetics; D017386:Sequence Homology, Amino Acid; D014404:Tubulin / Q000235:genetics
chemical_list: D001562:Benzimidazoles; D002219:Carbamates; D014404:Tubulin; C031000:benzimidazole; C006698:carbendazim