title: [Solitary intracerebral langerhans cell histiocytosis: report of one case and literature review].
abstract: BACKGROUND
  Langerhans cell histiocytosis is a multivisceral pathology. Neurological manifestations are rare.
  
  
  METHODS
  We report the case of a 31 year old man hospitalized for left partial motor seizure revealing a right frontal tumor with criteria for histiocytosis X. The histological and biological examination found criteria for Langerhans cell histiocytosis (CD1a and S100 reactivity). The check-up for extracerebral localisations of the disease was negative. The outcome was favourable after a total surgical resection. The review of the literature and a discussion on neurological manifestations of this disease were carried out.
  
  
  CONCLUSIONS
  A neurological manifestation can be the first and only symptom of a Langerhans cell histiocytosis.
authors.affiliation: Clinique neurologique, université de Poitiers, CHU de Poitiers, 2, rue de la Milétrie, 86021 Poitiers cedex 05, France. s.mathis@chu-poitiers.fr
authors.forename: S
authors.initials: S
authors.lastname: Mathis
authors.forename: P
authors.initials: P
authors.lastname: Levillain
authors.forename: P
authors.initials: P
authors.lastname: Vandermarcq
authors.forename: R
authors.initials: R
authors.lastname: Gil
authors.forename: V
authors.initials: V
authors.lastname: Auche
authors.forename: J
authors.initials: J
authors.lastname: Ciron
authors.forename: J-P
authors.initials: JP
authors.lastname: Neau
mesh_terms: D000328:Adult; D018949:Antigens, CD1 / Q000032:analysis; D001927:Brain Diseases / Q000473:pathology*; D006646:Histiocytosis, Langerhans-Cell / Q000473:pathology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D012640:Seizures / Q000209:etiology*
chemical_list: D018949:Antigens, CD1; C419393:CD1a antigen