title: A novel solid phase for selective separation of flavonoid compounds.
abstract: A novel straightforward approach to selective separation for flavonoid compounds was reported. The solid phase material was prepared by copolymerization using allyl-bromide-modified chitosan as macromonomer, and ethylene glycol dimethacrylate as cross-linker. The material was evaluated by chromatographic analysis; it exhibited high selectivity separation for quercetin and its structural analogues using different mobile phases. The material could directly trap a specific class of compounds including quercetin and kaempferol from the hydrolyzate of Ginkgo biloba extract. These results demonstrated the possibility of direct extraction of certain constituents from herb using this material.
authors.affiliation: Key Laboratory of Functional Polymer Materials, Ministry of Education, Institute of Polymer Chemistry, Nankai University, Tianjin, China.
authors.forename: Yong-Qing
authors.initials: YQ
authors.lastname: Xia
authors.forename: Tian-Ying
authors.initials: TY
authors.lastname: Guo
authors.forename: Hai-Li
authors.initials: HL
authors.lastname: Zhao
authors.forename: Mou-Dao
authors.initials: MD
authors.lastname: Song
authors.forename: Bang-Hua
authors.initials: BH
authors.lastname: Zhang
authors.forename: Bao-Long
authors.initials: BL
authors.lastname: Zhang
mesh_terms: D000327:Adsorption; D048271:Chitosan / Q000737:chemistry; D002851:Chromatography, High Pressure Liquid / Q000295:instrumentation; D005240:Feasibility Studies; D005419:Flavonoids / Q000737:chemistry / Q000302:isolation & purification*; D020441:Ginkgo biloba / Q000737:chemistry; D006868:Hydrolysis; D008689:Methacrylates / Q000737:chemistry; D010936:Plant Extracts / Q000032:analysis / Q000737:chemistry
chemical_list: D005419:Flavonoids; D008689:Methacrylates; D010936:Plant Extracts; C004919:ethylene dimethacrylate; D048271:Chitosan