[Clinical distribution and antibiotic resistance of non-fermentative Gram-negative bacilli infection after liver transplantation].
OBJECTIVE
To investigate the epidemiology of non-fermentative Gram-negative bacilli infections after liver transplantation, and to analyze the antibiotic susceptibility to major pathogens.


METHODS
A retrospective survey was conducted to 292 patients who underwent liver transplantation in the period of January 2004 and September 2006. With MicroScan Walkaway- 40 Automatic System, the non-fermentative Gram-negative bacilli infection was analyzed for the identification of pathogens and susceptibility to drugs.


RESULTS
Non-fermentative Gram-negative bacilli infection was identified in 33. 9% of 292 patients after liver transplantation. A total of 99 non-duplicate strains were isolated. The infection was frequently identified from respiratory tract, biliary tract, blood stream and intra-abdominal cavity. The top 3 pathogens were Acinetobacter baumannii, Pseudomonas aeruginosa and Stenotrophomonas maltophilia. Those non-fermentative Gram-negative bacilli were usually resistant to multiple antimicrobial agents.


CONCLUSIONS
The non-fermentative Gram-negative bacilli of postoperative infections in liver transplantation recipients are mostly multi-drug resistant. The microbiological surveillance is important for guiding clinical therapy.
Li
Jin
J
Center of Liver Transplantation, West China Hospital, Sichuan University, Chengdu 610041, China.
Yang
Jia-yin
JY
Yan
Lü-nan
LN
Wang
Wen-tao
WT
Xu
Ming-qing
MQ
Wu
Hong
H
D000293:Adolescent; D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D002648:Child; D002675:Child, Preschool; D024881:Drug Resistance, Bacterial; D005260:Female; D005285:Fermentation; D006090:Gram-Negative Bacteria / Q000187:drug effects* / Q000378:metabolism / Q000502:physiology*; D016905:Gram-Negative Bacterial Infections / Q000188:drug therapy / Q000453:epidemiology*; D006801:Humans; D016031:Liver Transplantation / Q000009:adverse effects; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000188:drug therapy / Q000453:epidemiology*; D055815:Young Adult
D000900:Anti-Bacterial Agents