title: Crimean-Congo hemorrhagic fever: five patients with hemophagocytic syndrome.
abstract: Three pediatric and two adult Turkish patients with Crimean Congo Hemorrhagic Fever (CCHF) induced hemophagocytic syndrome (HPS) were admitted to Ondokuz Mayis University Hospital, which is in the Middle Black Sea Region of Turkey. All of them had remarkable hemophagocytosis in the bone marrow with severe bleeding symptoms along with the other known clinical and laboratory findings of CCHF. We would like to present these patients and to discuss the pathophysiology and the effect of acquired HPS on the severity of the disease.
authors.affiliation: Department of Clinical Microbiology and Infectious Disease, Ondokuz Mayis University, Medical School, Samsun, Turkey. nuriyetf@omu.edu.tr
authors.forename: Nuriye
authors.initials: N
authors.lastname: Tasdelen Fisgin
authors.forename: Tunc
authors.initials: T
authors.lastname: Fisgin
authors.forename: Esra
authors.initials: E
authors.lastname: Tanyel
authors.forename: Levent
authors.initials: L
authors.lastname: Doganci
authors.forename: Necla
authors.initials: N
authors.lastname: Tulek
authors.forename: Nil
authors.initials: N
authors.lastname: Guler
authors.forename: Feride
authors.initials: F
authors.lastname: Duru
mesh_terms: D000293:Adolescent; D000368:Aged; D001853:Bone Marrow / Q000473:pathology; D002675:Child, Preschool; D005260:Female; D006479:Hemorrhagic Fever, Crimean / Q000473:pathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010586:Phagocytes / Q000473:pathology*; D013577:Syndrome