[Juvenile idiopathic arthritis and uveitis: epidemiology including data from a national database].
Uveitis is a potentially vision-threatening extra-articular manifestation of juvenile idiopathic arthritis (JIA) that manifests in approximately 13 % of all patients. According to the national ophthalmological and paediatric rheumatological database, one out of four children with JIA and uveitis develops ocular complications such as synechiae, band keratopathy, cataract, glaucoma and macula oedema. Independent risk factors of uveitis include the presence of a certain JIA subgroup, of antinuclear antibodies and age at onset. A late diagnosis, however, seems to be the relevant risk factor for uveitis complications in the course of the disease. The diagnosis of uveitis as early as possible is therefore the most important factor for a reduction of the morbidity of uveitis. Due to the usual lack of symptoms the diagnosis of uveitis requires, however, an examination by an ophthalmologist. This should be done immediately after the diagnosis of JIA and repeated in a risk-adapted manner during the follow-up.
Minden
K
K
Deutsches Rheuma-Forschungszentrum Berlin, Charitéplatz 1, Berlin. Minden@drfz.de
Mingels
A
A
Niewerth
M
M
Heiligenhaus
A
A
Ganser
G
G
D001171:Arthritis, Juvenile / Q000175:diagnosis* / Q000453:epidemiology*; D002648:Child; D015897:Comorbidity; D016208:Databases, Factual; D005858:Germany / Q000453:epidemiology; D006801:Humans; D015995:Prevalence; D012042:Registries; D018570:Risk Assessment / Q000379:methods*; D012307:Risk Factors; D014605:Uveitis / Q000175:diagnosis* / Q000453:epidemiology*