title: Chemical interaction between titanium implant surface and amino acids.
abstract: The purpose of this study was to investigate the chemical interaction between titanium implant surface and amino acids. Pure titanium disks were pretreated with 10 N HCl and ultrapure water at room temperature for 30 minutes each. Disks were then modified with one of the three amino acids--L-aspartic acid, L-serine, or L-threonine--at 37 degrees C for 12 hours. Modification with oxalic acid was used as a control. By means of X-ray photoelectron spectroscopy (XPS), amino acid powders and the modified surfaces without or with ultrasonic water rinsing were chemically analyzed. It was revealed that the N 1s peak which originated from amino acids was not or hardly detected in the wide scan spectra of amino acid-modified surfaces. Moreover, the COO- peak which originated from oxalic acid could hardly be detected in the narrow scan spectrum of the C is region of oxalic acid-modified surface with ultrasonic water rinsing. Based on the results of this study, it was concluded that amino acids could not chemically bond to the titanium surface.
authors.affiliation: Department of Advanced Prosthodontics, Division of Cervico-Gnathostomatology, Graduate School of Biomedical Sciences, Hiroshima University, 1-2-3, Kasumi, Minami-ku, Hiroshima 734-8553, Japan.
authors.forename: Kyou
authors.initials: K
authors.lastname: Hiasa
authors.forename: Yasuhiko
authors.initials: Y
authors.lastname: Abe
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Yoshida
authors.forename: Tsuyoshi
authors.initials: T
authors.lastname: Taji
authors.forename: Kazuomi
authors.initials: K
authors.lastname: Suzuki
authors.forename: Yasumasa
authors.initials: Y
authors.lastname: Akagawa
mesh_terms: D000596:Amino Acids / Q000737:chemistry*; D001224:Aspartic Acid / Q000737:chemistry; D002245:Carbon Dioxide / Q000737:chemistry; D015921:Dental Implants; D004577:Electron Probe Microanalysis; D008422:Materials Testing; D015394:Molecular Structure; D009584:Nitrogen / Q000032:analysis; D012694:Serine / Q000737:chemistry; D013499:Surface Properties; D013912:Threonine / Q000737:chemistry; D014025:Titanium / Q000737:chemistry*
chemical_list: D000596:Amino Acids; D015921:Dental Implants; D002245:Carbon Dioxide; C041069:carboxyl radical; D013912:Threonine; D001224:Aspartic Acid; D012694:Serine; D014025:Titanium; D009584:Nitrogen