A review of the management by hysterectomy of 25 cases of gestational trophoblastic tumours from March 1993 to January 2006.
We reviewed 25 cases of gestational trophoblastic tumours referred for surgical management from Charing Cross Hospital (the London centre for gestational trophoblastic disease [GTD]) over a 13-year period. The operation performed was total abdominal hysterectomy, with lymph node sampling in 9/25 (36%) women and bilateral salpingo-oophorectomy in 11/25 (44%) women. Radical hysterectomy and unilateral parametrectomy was required in 3/25 (12%) women. Three of 25 (12%) women failed to survive, i.e. the overall rate of survival was 88%. Management by hysterectomy of primary drug-resistant and relapse cases of GTD is a useful and safe adjunct to chemotherapy.
Doumplis
D
D
West London Gynaecological Cancer Centre, Hammersmith Hospital NHS Trust, London, UK.
Al-Khatib
K
K
Sieunarine
K
K
Lindsay
I
I
Seckl
M
M
Bridges
J
J
Smith
J R
JR
D000328:Adult; D005260:Female; D031901:Gestational Trophoblastic Disease / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D006801:Humans; D007044:Hysterectomy / Q000379:methods*; D008113:Liver Neoplasms / Q000401:mortality / Q000556:secondary; D008175:Lung Neoplasms / Q000401:mortality / Q000556:secondary; D008197:Lymph Node Excision / Q000379:methods; D008207:Lymphatic Metastasis; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000401:mortality / Q000473:pathology; D009367:Neoplasm Staging; D011247:Pregnancy