title: Experimental study of sensitivity enhancement in surface plasmon resonance biosensors by use of periodic metallic nanowires.
abstract: We have experimentally confirmed sensitivity enhancement of a nanowire-based surface plasmon resonance (SPR) sensor structure. Gold nanowires with periods of 200 and 500 nm were fabricated, respectively, by electron-beam and interference lithography on a gold/SF10 substrate. Sensitivity enhancement was measured to be 44% compared with a conventional thin-film-based SPR structure for nanowires of 200 nm period and 31% for 500 nm when evaluated using ethanol at a varied concentration. This result is consistent with numerical data. Surface roughness is responsible for sensitivity reduction by more than 10%. More significant sensitivity improvement can be achieved by inducing strong localized plasmon coupling with finer nanowires.
authors.affiliation: School of Electrical Engineering and Computer Science, Seoul National University, Seoul 151-742, Korea.
authors.forename: Kyung Min
authors.initials: KM
authors.lastname: Byun
authors.forename: Soon Joon
authors.initials: SJ
authors.lastname: Yoon
authors.forename: Donghyun
authors.initials: D
authors.lastname: Kim
authors.forename: Sung June
authors.initials: SJ
authors.lastname: Kim
mesh_terms: D015374:Biosensing Techniques / Q000295:instrumentation / Q000379:methods*; D000431:Ethanol / Q000737:chemistry*; D006046:Gold / Q000737:chemistry*; D053770:Nanowires / Q000737:chemistry*; D020349:Surface Plasmon Resonance / Q000295:instrumentation / Q000379:methods*
chemical_list: D000431:Ethanol; D006046:Gold