Necrospermia, antisperm antibodies, and vasectomy.
OBJECTIVE
To present a case of necrospermia and antisperm antibodies after vasectomy reversal and in which motile sperm, subsequently used in intracytoplasmic sperm injection (ICSI) treatment, was found after testicular sperm retrieval.


METHODS
Case report and literature review.


METHODS
Reproductive medicine unit based in a women's hospital in the United Kingdom.


METHODS
A 36-year-old man with secondary infertility who presented with necrospermia and antisperm antibodies after vasectomy reversal.


METHODS
Testicular sperm retrieval and IVF with ICSI.


METHODS
Presence of motile sperm in testicular sperm extraction biopsies.


RESULTS
Motile sperm found after testicular sperm retrieval successfully fertilized oocytes in an ICSI cycle.


CONCLUSIONS
It appears difficult to dissociate the presence of antisperm antibodies from the necrospermia in our patient. Testicular sperm retrieval appeared to partially overcome the effect of the antisperm antibodies by retrieving sperm before they reach seminal plasma, where they would be exposed to the antibodies.
Chavez-Badiola
Alejandro
A
Hewitt Centre for Reproductive Medicine, Liverpool Women's Hospital, Liverpool, Merseyside, United Kingdom. alejandro_bad@yahoo.it
Drakeley
Andrew John
AJ
Finney
Victoria
V
Sajjad
Yasmin
Y
Lewis-Jones
David Iwan
DI
D000328:Adult; D001323:Autoantibodies / Q000097:blood*; D004624:Embryo Transfer; D005260:Female; D006801:Humans; D007248:Infertility, Male / Q000276:immunology / Q000473:pathology / Q000503:physiopathology / Q000628:therapy*; D008297:Male; D010062:Ovulation Induction; D011247:Pregnancy; D012661:Semen / Q000276:immunology; D020554:Sperm Injections, Intracytoplasmic; D013081:Sperm Motility; D053625:Sperm Retrieval; D013094:Spermatozoa / Q000276:immunology* / Q000473:pathology; D017211:Treatment Failure; D014659:Vasectomy; D014669:Vasovasostomy
D001323:Autoantibodies