Sequence of GDF 8 (myostatin) gene in Bubalus bubalis.
The sequence of myostatin gene (growth differentiation factor 8 [GDF 8]) in Indian riverine buffalo (Bubalus bubalis) is reported. The genomic DNA as well as mRNA were sequenced. The sequence is conserved across all the livestock species. Five nonsynonymous changes as compared to cattle were found in this study and were also confirmed by mRNA sequence. Two intronic single nucleotide polymorphisms (SNPs) were identified in buffalo.
Tantia
M S
MS
National Bureau of Animal Genetic Resources, Karnal, Haryana, India. mstantia@yahoo.com
Vijh
R K
RK
Mishra
B
B
Kumar
S T Bharani
ST
D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D002020:Buffaloes / Q000235:genetics*; D004247:DNA / Q000737:chemistry / Q000235:genetics; D008969:Molecular Sequence Data; D018482:Muscle, Skeletal / Q000502:physiology; D055435:Myostatin; D016133:Polymerase Chain Reaction / Q000662:veterinary; D012150:Polymorphism, Restriction Fragment Length; D020641:Polymorphism, Single Nucleotide; D016415:Sequence Alignment; D016212:Transforming Growth Factor beta / Q000235:genetics*
D055435:Myostatin; D016212:Transforming Growth Factor beta; D004247:DNA