Palladium-catalysed regioselective addition reaction of ethyl phenylphosphinate with terminal acetylenes: ligand- and solvent-dependent regioselectivity.
Palladium-1,2-bis(diphenylphosphino)ethane complex catalyses regioselective Markovnikov addition of ethyl phenylphosphinate to terminal alkynes in toluene, while the use of tri-tert-butylphosphine as the ligand or ethanol as the solvent leads to regioselectivity reversal.
Kumar Nune
Satish
S
Chemical Resources Laboratory, Tokyo Institute of Technology, 4259-R1-13 Nagatsuta, Midori-ku, Yokohama 226-8503, Japan.
Tanaka
Masato
M