Liver transplantation for metabolic liver diseases.
Liver transplantation has become an accepted treatment for several metabolic liver diseases. With advances in organ transplantation and immunosuppressive strategies, survival rates following liver transplantation are generally excellent. When the primary metabolic defect is hepatic in origin, liver transplantation not only replaces the dysfunctional organ but also cures the underlying metabolic defect. For conditions in which the primary metabolic defect is extrahepatic, liver transplantation is usually performed for hepatic complications, although disease recurrence may occur. This article reviews common metabolic liver diseases treated with liver transplantation in the adult population.
Zhang
Kristine Y
KY
Division of Gastroenterology and Hepatology, University of Washington School of Medicine, 1959 NE Pacific Street, Box 356424, Seattle, WA 98195, USA.
Tung
Bruce Y
BY
Kowdley
Kris V
KV
D028227:Amyloid Neuropathies, Familial / Q000150:complications; D003550:Cystic Fibrosis / Q000150:complications; D006432:Hemochromatosis / Q000150:complications; D006527:Hepatolenticular Degeneration / Q000601:surgery*; D006801:Humans; D008107:Liver Diseases / Q000209:etiology* / Q000601:surgery*; D016031:Liver Transplantation; D019896:alpha 1-Antitrypsin Deficiency / Q000150:complications