title: Modern screening in cervical cancer. Perspectives of HPV prophylactic vaccines.
abstract: Despite the tremendous progress made along several different lines of research, cervical cancer has not has been overcome. The presence or the absence of the HR-HPV infection defines new possible approaches to screen and prevent cervical cancer. The aim of this review is to summarize the mechanisms that contribute to HPV-mediated cervical carcinogenesis, to present the modern screening in cervical cancer (liquid-based cytology, liquid-based hybridization, PCR-based assays) and also the beginning of the HPV vaccine era.
authors.affiliation: Obstetrics and Gynecology Department, Elias Univesitary Emergency Hospital, Bucucureşti.
authors.forename: R
authors.initials: R
authors.lastname: Vlădăreanu
authors.forename: Cr
authors.initials: C
authors.lastname: Andrei
mesh_terms: D005260:Female; D052162:Human papillomavirus 16 / Q000235:genetics / Q000472:pathogenicity; D052161:Human papillomavirus 18 / Q000235:genetics / Q000472:pathogenicity; D006801:Humans; D017403:In Situ Hybridization; D008403:Mass Screening / Q000379:methods*; D030361:Papillomavirus Infections / Q000517:prevention & control* / Q000821:virology; D053918:Papillomavirus Vaccines / Q000276:immunology / Q000627:therapeutic use*; D016133:Polymerase Chain Reaction; D002583:Uterine Cervical Neoplasms / Q000175:diagnosis* / Q000517:prevention & control* / Q000821:virology; D014626:Vaginal Smears
chemical_list: D053918:Papillomavirus Vaccines