title: Is diagnostic tonsillectomy indicated in all children with asymmetrically enlarged tonsils?
abstract: OBJECTIVE
  The aims of the study were: (i) to determine the necessity for diagnostic tonsillectomy in children with asymmetrically enlarged tonsils; (ii) to determine the accuracy of clinical assessment of tonsillar asymmetry; and (iii) to determine how to manage children with clinical tonsillar asymmetry in a developing-world practice.
  
  
  METHODS
  A prospective study was carried out at Red Cross War Memorial Children's Hospital in Cape Town, over an 8-month period. All children undergoing tonsillectomy or adenotonsillectomy had a clinical assessment of tonsil symmetry done, and all tonsil and adenoid specimens were examined histologically. The maximum diameter and volume of the resected tonsils were measured. A comparison was done of true tonsil asymmetry in patients with asymmetrical tonsils and a subgroup of matched controls with symmetrical tonsils.
  
  
  RESULTS
  A total of 344 tonsils were analysed (172 patients). The 13 patients (7.6%) diagnosed as having clinically asymmetrically enlarged tonsils had no significant pathological diagnosis. In the patients with symmetrical tonsils there were 2 abnormal pathological findings (tuberculosis of the adenoids and T-cell lymphoma of the tonsils and adenoids). In the clinically asymmetrical tonsil group, true tonsillar asymmetry was 3 mm (maximum diameter), and 2.2 cm(3) (volume), compared with 1.9 mm and 1.5 cm(3) in the symmetrical tonsil group. When patients with clinical tonsillar asymmetry and symmetry were compared, the difference in maximum diameter (p = 0.62) and volume (p = 0.73) was not significantly different.
  
  
  CONCLUSIONS
  Clinical tonsillar asymmetry is usually apparent rather than real. The incidence of significant pathology in children with asymptomatic, asymmetrical tonsils is low. Diagnostic tonsillectomy is indicated in children with asymmetrically enlarged tonsils associated with constitutional symptoms, cervical lymphadenopathy, rapid tonsil enlargement or significant tonsillar asymmetry.
authors.affiliation: Division of Otorlaryngology, University of Cape Town, South Africa. antonv1@worldonline.co.za
authors.forename: Anton C
authors.initials: AC
authors.lastname: van Lierop
authors.forename: C A J
authors.initials: CA
authors.lastname: Prescott
authors.forename: Johannes J
authors.initials: JJ
authors.lastname: Fagan
authors.forename: Colin C
authors.initials: CC
authors.lastname: Sinclair-Smith
mesh_terms: D000234:Adenoids / Q000473:pathology / Q000601:surgery; D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D006984:Hypertrophy; D007223:Infant; D008297:Male; D014066:Palatine Tonsil / Q000473:pathology* / Q000601:surgery; D011446:Prospective Studies; D014068:Tonsillectomy