title: Cryptosporidium parvum-associated sclerosing cholangitis in a liver transplant patient.
abstract: Cryptosporidium parvum causes severe long-standing diarrhea in immunocompromised patients. Sclerosing cholangitis caused by C. parvum is a rare complication in transplant recipients. We report herein the presentation of Cryptosporidium-associated cholangitis in an adult liver transplant patient diagnosed by liver biopsy. The patient improved on treatment with azithromycin and paromomycin.
authors.affiliation: Beth Israel Deaconess Medical Center, Harvard University, Boston, Massachusetts 02215, USA. cdenking@bidmc.harvard.edu
authors.forename: C M
authors.initials: CM
authors.lastname: Denkinger
authors.forename: P
authors.initials: P
authors.lastname: Harigopal
authors.forename: P
authors.initials: P
authors.lastname: Ruiz
authors.forename: L M
authors.initials: LM
authors.lastname: Dowdy
mesh_terms: D000818:Animals; D017963:Azithromycin / Q000627:therapeutic use; D015209:Cholangitis, Sclerosing / Q000188:drug therapy / Q000469:parasitology*; D003457:Cryptosporidiosis / Q000150:complications*; D016785:Cryptosporidium parvum / Q000472:pathogenicity*; D006801:Humans; D016867:Immunocompromised Host; D016031:Liver Transplantation / Q000009:adverse effects / Q000276:immunology*; D008297:Male; D008875:Middle Aged; D010303:Paromomycin / Q000627:therapeutic use; D016896:Treatment Outcome
chemical_list: D010303:Paromomycin; D017963:Azithromycin