[Clinical research of effect of Yishen Yangnao capsule on vascular dementia].
OBJECTIVE
To find a good way to diagnose VD, value the effect of Yishen Yangnao capsule on VD and try to find some rules of changes in Chinese medicine syndromes.


METHODS
Patients were randomly divided into treating group and western medicine comparison group. It's the phase III clinical research of Rishen Yangnao capsule curing VD, judging the validity and security of it, using dukexi slice as comparison drug. Some of the patients did the examination of P300.


RESULTS
The total validity of Yishen Yangnao capsule is 56.3% (contract team is 60.0%). The improve rate of ADL is 0.1069% (contract team is 0.1134%). The scores of Chinese medicine syndrome descend.


CONCLUSIONS
Yishen Yangnao capsule has the same effect as dukexi slice in curing VD at the side of intelligence situation and life ability.
Xu
Wen-jie
WJ
Internal Medicine of Nerve of Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100700, China.
Li
Zong-heng
ZH
Shi
Yong-mei
YM
Zou
Yi-huai
YH
D000203:Activities of Daily Living; D000368:Aged; D015765:Almitrine / Q000627:therapeutic use; D002214:Capsules; D015140:Dementia, Vascular / Q000188:drug therapy* / Q000503:physiopathology; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification / Q000627:therapeutic use*; D018913:Event-Related Potentials, P300; D005260:Female; D006801:Humans; D008297:Male; D008516:Medicine, Chinese Traditional / Q000379:methods; D008875:Middle Aged; D018696:Neuroprotective Agents / Q000302:isolation & purification / Q000627:therapeutic use*; D008517:Phytotherapy; D016896:Treatment Outcome; D015016:Yohimbine / Q000627:therapeutic use
D002214:Capsules; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal; D018696:Neuroprotective Agents; C528936:yishen yangnao; D015016:Yohimbine; C037558:almitrine, raubasine drug combination; D015765:Almitrine