title: Comparative study of the specificities of needling acupoints DU20, DU26 and HT7 in intervening vascular dementia in different areas in the brain on the basis of scale assessment and cerebral functional imaging.
abstract: OBJECTIVE
  Using methods of clinical scale assessment and cerebral functional imaging to compare the relative specificity of needling acupoints Baihui (DU20), Shuigou (DU26) and Shenmen (HT7) in intervening vascular dementia (VD) in different areas in the brain.
  
  
  METHODS
  Fifty patients with VD were randomized into 5 groups. Needling on conventionally used acupoints of hand and foot three Yang-meridians aiming at hemiplegia was applied to the patients in Group A, and needling on DU20 to Group B, on DU26 to Group C, on HT7 to Group D and on all the three to Group E was applied additionally. Assessments of Mini Mental State Examination (MMSE), Activities of Daily Living (ADL) and Family Attitude Questionnaire (FAQ) were made. And the positron emission computerized tomography (PET) and single photon emission computerized tomography (SPECT) examinations were conducted in 5 selected patients from each group before and after treatment.
  
  
  RESULTS
  Needling on conventional acupoints plus DU20 could effect the inner temporal system, thalamencephalon system and prefrontal cortical system to improve memory and executive capacity of VD patients; conventional acupoints plus DU26 could effect more to the prefrontal cortical system to obviously elevate the executive capacity; that plus HT7 would reveal an effect similar to but rather weaker than plus DU20, and effect more to memory; and that plus all the three simultaneously could effect rather roundly multiple aspects of the nervous system related to intellectual activities, to elevate the recognition and enhance the executive capacity.
  
  
  CONCLUSIONS
  Needling on various acupoints like DU20, DU26 and HT7 have effects on different brain areas.
authors.affiliation: TCM College of Nanfang Medical University, Guangzhou, 510515, China.
authors.forename: Yong
authors.initials: Y
authors.lastname: Huang
authors.forename: Xin-sheng
authors.initials: XS
authors.lastname: Lai
authors.forename: An-wu
authors.initials: AW
authors.lastname: Tang
mesh_terms: D000203:Activities of Daily Living; D015669:Acupuncture Points; D015670:Acupuncture Therapy / Q000379:methods*; D000368:Aged; D001921:Brain / Q000000981:diagnostic imaging / Q000503:physiopathology*; D002560:Cerebrovascular Circulation; D015140:Dementia, Vascular / Q000503:physiopathology / Q000628:therapy*; D005260:Female; D005947:Glucose / Q000378:metabolism; D006801:Humans; D008297:Male; D008875:Middle Aged; D011877:Radionuclide Imaging
chemical_list: D005947:Glucose