title: Surgical treatment of childhood recurrent pancreatitis.
abstract: OBJECTIVE
  Surgical intervention that improves pancreatic ductal drainage is a reasonable treatment strategy for recurrent pancreatitis in children.
  
  
  METHODS
  This study was approved by the Committee on Human Research (San Francisco, CA). A retrospective chart review was performed on children aged 0 to 17 years given the International Classification of Diseases, Ninth Revision coding diagnosis of chronic pancreatitis who underwent surgical intervention from 1981 to 2005.
  
  
  RESULTS
  From 1981 to 2005, 32 children were treated for the diagnosis of chronic pancreatitis. The etiologies were obstructive (n = 13), idiopathic (n = 10), hereditary (n = 6), medications (n = 2), and infection (n = 1). Fifteen patients underwent 17 operations for chronic pancreatitis, including Puestow (n = 9), cystenterostomy (n = 2), Whipple (n = 1), distal pancreatectomy (n = 1), Frey (n = 1), DuVal (n = 1), excision of enteric duplication cyst (n = 1), and pancreatic ductal dilation (n = 1). The mean age at presentation of patients undergoing surgery was 6.0 +/- 4.1 years (mean +/- SD). The mean time from presentation to operation was 3.3 +/- 3.3 years. There were no deaths after surgical intervention. Of 15 patients, 2 (13%) required rehospitalization within 90 days of surgery, one for bowel obstruction, the other for splenic infarction. The median length of stay postoperatively was 8 days (range, 5-66 days).
  
  
  CONCLUSIONS
  Chronic pancreatitis in children differs markedly in etiology when compared with adults. In most cases seen in our institution, chronic pancreatitis resulted from ineffective ductal drainage. These disorders are amenable to surgical decompression, which, ultimately, can prevent disease recurrence.
authors.affiliation: Division of Pediatric Surgery, Department of Surgery, University of California San Francisco, Box 0570, San Francisco, CA 94143-0570, USA.
authors.forename: Matthew S
authors.initials: MS
authors.lastname: Clifton
authors.forename: Juan C
authors.initials: JC
authors.lastname: Pelayo
authors.forename: Raul A
authors.initials: RA
authors.lastname: Cortes
authors.forename: Erich J
authors.initials: EJ
authors.lastname: Grethel
authors.forename: Amy J
authors.initials: AJ
authors.lastname: Wagner
authors.forename: Hanmin
authors.initials: H
authors.lastname: Lee
authors.forename: Michael R
authors.initials: MR
authors.lastname: Harrison
authors.forename: Diana L
authors.initials: DL
authors.lastname: Farmer
authors.forename: Kerilyn K
authors.initials: KK
authors.lastname: Nobuhara
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D050500:Pancreatitis, Chronic / Q000209:etiology / Q000601:surgery*; D012008:Recurrence; D012189:Retrospective Studies; D016896:Treatment Outcome