Indomethacin for recurrent cutaneous necrotizing eosinophilic vasculitis.
Recurrent cutaneous necrotizing eosinophilic vasculitis (RCNEV) is a rare disease characterized by clinical features of pruritic purpuric papules and angioedema. Skin biopsies revealed the eosinophil-predominate necrotizing vasculitis affecting small dermal vessels. Systemic corticosteroid is a very effective treatment. There are many side effects associated with systemic corticosteroid therapy. The authors report a case of RCNEVsuccessfully treated with indomethacin. To the authors'knowledge, there has been no reported case of RCNEV treated with indomethacin.
Tanglertsampan
Chuchai
C
Skin Center, Bum- rungrad International Hospital, 33 Sukhumvit 3, Wattana, Bangkok 10110, Thailand. drchuchait@yahoo.com
Tantikun
Niyom
N
Noppakun
Nopadon
N
Pinyopornpanit
Virat
V
D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use*; D004802:Eosinophilia / Q000188:drug therapy / Q000473:pathology*; D004804:Eosinophils; D006801:Humans; D007213:Indomethacin / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D009336:Necrosis / Q000188:drug therapy* / Q000473:pathology; D012008:Recurrence; D017445:Skin Diseases, Vascular / Q000188:drug therapy* / Q000473:pathology; D014657:Vasculitis / Q000188:drug therapy* / Q000473:pathology
D000894:Anti-Inflammatory Agents, Non-Steroidal; D007213:Indomethacin