Castleman disease presenting with jaundice: a case with the multicentric hyaline vascular variant.
Castleman disease (CD) is a rare lymphoproliferative disorder of unknown etiology with different clinical manifestations. A previous healthy 50 year-old man was hospitalized for right upper quadrant (RUQ) abdominal pain. He had jaundice and a 1 cm-sized lymph node in the right supraclavicular area. Pancreas and biliary computed tomography (CT) showed masses at the right renal hilum and peripancreatic areas. Positron emission tomography (PET) showed widespread systemic lymphadenopathy. Excisional biopsy of the right supraclavicular node revealed a hyaline vascular variant of CD. Corticosteroid therapy was started and the extent of disease decreased. We here report a case of multicentric CD, the hyaline vascular variant, presenting with jaundice, diagnosed by excisional biopsy and successfully treated with corticosteroids.
Park
Jun Bean
JB
Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.
Hwang
Jin Hyeok
JH
Kim
Haeryoung
H
Choe
Hyung Sim
HS
Kim
Yu Kyeong
YK
Kim
Hong Bin
HB
Bang
Soo-Mee
SM
D015746:Abdominal Pain / Q000209:etiology; D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D001706:Biopsy; D005871:Castleman Disease / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D006801:Humans; D007565:Jaundice / Q000150:complications*; D008297:Male; D008875:Middle Aged; D049268:Positron-Emission Tomography; D014057:Tomography, X-Ray Computed; D014652:Vascular Diseases / Q000175:diagnosis* / Q000473:pathology
D000305:Adrenal Cortex Hormones