Cutaneous and meningeal sporotrichosis in a HIV patient.
A male patient with HIV and past history of tuberculosis and suspected neurotoxoplasmosis was admitted to the hospital with vomiting and small nodules through all his body. Few of the nodules were found forming chains of enlarged lymphatic vessels, especially on lesions located on the limbs. Some of the nodules were ulcerated with a serosanguineous discharge. Collected samples from ulcerated and the nodular lesions showed the presence of Sporothrix schenckii in culture. Although all hemocultures were negative, a spinal fluid collected from this patient and cultures from the cutaneous lesions were both positive for S. schenckii. The patient showed improvement after treatment with Amphotericin B. Sadly, he later died of complications not related to the S. schenckii infection. This case of disseminated sporotrichosis is a remainder that in patients with immunological disorders exotic forms of this fungal clinical entity could be expected.
Vilela
Raquel
R
Hospital Eduardo de Menezes, Medical Mycology Laboratory, Belo Horizonte, Brazil.
Souza
Guenael F
GF
Fernandes Cota
Gláucia
G
Mendoza
Leonel
L
D017088:AIDS-Related Opportunistic Infections / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D000328:Adult; D000666:Amphotericin B / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use; D002180:Candidiasis, Oral / Q000150:complications; D002555:Cerebrospinal Fluid / Q000382:microbiology; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D006801:Humans; D008297:Male; D016921:Meningitis, Fungal / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D012867:Skin / Q000382:microbiology; D013174:Sporotrichosis / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D016781:Toxoplasmosis, Cerebral / Q000175:diagnosis
D000935:Antifungal Agents; D000666:Amphotericin B