Dengue hemorrhagic shock and disseminated candidiasis.
Dengue fever, one of the common endemic viral fevers, often presents with fever, rash, and mild liver dysfunction. However, plasma leakage induced by dengue virus infection can lead to dengue hemorrhagic fever and dengue shock syndrome, and it can cause severe complications including liver failure and encephalopathy. Infection of dengue virus with other pathogens is an unusual but serious complication. We report a case of dengue shock syndrome with liver failure and impaired consciousness. The patient developed a disseminated Candida tropicalis infection, which may have been due to translocation of the fungus from the intestine damaged by the dengue virus.
Suzuki
Satoshi
S
Department of Infectious Diseases, Graduate School of Medicine, The University of Tokyo.
Kitazawa
Takatoshi
T
Ota
Yasuo
Y
Okugawa
Shu
S
Tsukada
Kunihisa
K
Nukui
Yoko
Y
Hatakeyama
Shuji
S
Yamaguchi
Daisuke
D
Matsuse
Shinji
S
Ishii
Takeshi
T
Matsubara
Takehiro
T
Yamauchi
Chisako
C
Ota
Satoshi
S
Yahagi
Naoki
N
Fukayama
Masashi
M
Koike
Kazuhiko
K
D001707:Biopsy, Needle; D001774:Blood Chemical Analysis; D002177:Candidiasis / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D003131:Combined Modality Therapy; D018450:Disease Progression; D017809:Fatal Outcome; D016469:Fungemia / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D006801:Humans; D007150:Immunohistochemistry; D007564:Japan; D017093:Liver Failure / Q000150:complications / Q000175:diagnosis* / Q000628:therapy; D008297:Male; D008875:Middle Aged; D019595:Severe Dengue / Q000150:complications / Q000175:diagnosis* / Q000628:therapy; D012720:Severity of Illness Index; D012771:Shock, Hemorrhagic / Q000150:complications / Q000175:diagnosis* / Q000628:therapy; D014057:Tomography, X-Ray Computed