World's longest surviving liver-pancreas recipient.
In July 1988, the liver and pancreas of a cadaveric donor were transplanted separately into a man with type 1 diabetes with end-stage chronic hepatitis B virus. Two features of the operation may help explain the patient's current status as the longest-lived liver-pancreas recipient. One was enteric drainage of pancreatic exocrine secretions. The other was delivery of the pancreas venous effluent to the host portal system and then directly to the hepatic allograft.
Harary
Albert M
AM
New York University School of Medicine and Lenox Hill Hospital, New York, NY, USA.
Abu-Elmagd
Kareem
K
Thai
Ngoc
N
Shapiro
Ron
R
Todo
Satoru
S
Fung
John J
JJ
Starzl
Thomas E
TE
D000293:Adolescent; D003922:Diabetes Mellitus, Type 1 / Q000150:complications / Q000601:surgery*; D019694:Hepatitis B, Chronic / Q000150:complications / Q000601:surgery*; D006801:Humans; D016031:Liver Transplantation / Q000379:methods / Q000502:physiology*; D008297:Male; D016035:Pancreas Transplantation / Q000379:methods / Q000502:physiology*; D017741:Survivors; D013997:Time Factors; D016896:Treatment Outcome