Synthesis of 2,3-dihydro-10bh-oxazolo[2,3-a]isoquinolines from ortho-lithiated phenyloxazolinyloxiranes.
A general method for the synthesis of 2,3-dihydro-10bH-oxazolo[2,3-a]isoquinolines from the reaction of (R*,R*)-configured ortho-bromophenyloxazolinyloxiranes and organolithiums is described.
Capriati
Vito
V
Dipartimento Farmaco-Chimico, Università di Bari, C.N.R., Istituto di Chimica dei Composti OrganoMetallici, Sezione di Bari, Via E. Orabona 4, I-70125 Bari, Italy.
Florio
Saverio
S
Luisi
Renzo
R
Perna
Filippo Maria
FM
D000473:Alkanes / Q000737:chemistry; D002625:Chemistry, Organic / Q000379:methods*; D005027:Ethylene Oxide / Q000138:chemical synthesis* / Q000737:chemistry*; D007546:Isoquinolines / Q000138:chemical synthesis* / Q000737:chemistry*; D008094:Lithium / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D008956:Models, Chemical; D010080:Oxazoles / Q000138:chemical synthesis* / Q000737:chemistry*
D000473:Alkanes; D007546:Isoquinolines; D010080:Oxazoles; D008094:Lithium; D005027:Ethylene Oxide