Women who experience detrusor overactive at lower bladder volumes report greater bother.
OBJECTIVE
To explore the relationship of cystometric volume at the time of first detection of detrusor overactive incontinence (DOI) to condition-specific quality of life (QOL).


METHODS
We reviewed consecutive charts of women diagnosed with pure DOI during urodynamic testing. DOI volume was defined as the cystometric volume at the first detection of DOI. Responses to the Urine Distress Inventory (UDI6) and Incontinence Impact Questionnaire (IIQ7) were recorded. Spearman correlations were used to compare independent groups with respect to continuous variables.


RESULTS
Eighty-nine women were included in this analysis. DOI volume was inversely correlated with UDI6 and IIQ7 scores (Spearman's rho = -0.514, P < 0.001 and Spearman's rho = -0.611, P < 0.001). Maximal cystometric capacity was also inversely correlated with UDI6 and IIQ7 scores (rho = -0.458, P < 0.0001 and Spearman's rho = -0.43, P < 0.0001).


CONCLUSIONS
Women who experience DOI at lower volumes during urodynamics report greater bother and QOL impact from incontinence than women who leak at higher volumes.
Lowenstein
Lior
L
Department of Obstetrics and Gynecology, Division of Female Pelvic Medicine and Reconstructive Surgery, Loyola University Medical Center, Maywood, Illinois 60153, USA. llowenstein@lumc.edu.
Kenton
Kimberly
K
Dooley
Yashika
Y
R Mueller
Elizabeth
E
Brubaker
Linda
L
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D016014:Linear Models; D008875:Middle Aged; D011788:Quality of Life; D012189:Retrospective Studies; D012720:Severity of Illness Index; D001743:Urinary Bladder / Q000473:pathology* / Q000503:physiopathology; D053201:Urinary Bladder, Overactive / Q000503:physiopathology*; D014550:Urinary Incontinence, Stress / Q000503:physiopathology*; D014563:Urodynamics / Q000502:physiology