title: Self-reported medical conditions in perfluorooctanesulfonyl fluoride manufacturing workers.
abstract: OBJECTIVE
  To evaluate whether some cancers, other conditions, and pregnancy outcomes were related to occupational perfluorooctane sulfonate (PFOS) exposure.
  
  
  METHODS
  We surveyed current and former employees of a perfluorooctanesulfonyl fluoride production facility, using a self-administered questionnaire to ascertain several cancers and health conditions. Female cohort members also completed a brief pregnancy history. We requested medical records to validate reported melanoma, breast, prostate, and colon cancers. PFOS exposure was estimated based on a job exposure matrix up to the year of the diagnosis of the condition.
  
  
  RESULTS
  Of the 1,895 eligible participants, 1,400 questionnaires were returned. No association was observed between working in a PFOS-exposed job and the risk of any of the surveyed conditions.
  
  
  CONCLUSIONS
  We observed no association between working in a PFOS-exposed job and several cancers, common health conditions, and birth weight.
authors.affiliation: University of Minnesota, School of Public Health, Division of Environmental Health Sciences, Minneapolis, Minnesota 55455, USA.
authors.forename: Mira M
authors.initials: MM
authors.lastname: Grice
authors.forename: Bruce H
authors.initials: BH
authors.lastname: Alexander
authors.forename: Richard
authors.initials: R
authors.lastname: Hoffbeck
authors.forename: Diane M
authors.initials: DM
authors.lastname: Kampa
mesh_terms: D000328:Adult; D000368:Aged; D017738:Alkanesulfonic Acids / Q000506:poisoning*; D005260:Female; D005466:Fluorocarbons / Q000506:poisoning*; D006304:Health Status; D006306:Health Surveys; D006801:Humans; D008297:Male; D008875:Middle Aged; D008910:Minnesota; D016273:Occupational Exposure / Q000009:adverse effects*; D012650:Self Disclosure
chemical_list: D017738:Alkanesulfonic Acids; D005466:Fluorocarbons; C076994:perfluorooctane sulfonic acid