title: Prevention of catheter-related blood stream infection.
abstract: OBJECTIVE
  Catheter-related blood stream infections are a morbid complication of central venous catheters. This review will highlight a comprehensive approach demonstrated to prevent catheter-related blood stream infections.
  
  
  RESULTS
  Elements of prevention important to inserting a central venous catheter include proper hand hygiene, use of full barrier precautions, appropriate skin preparation with 2% chlorhexidine, and using the subclavian vein as the preferred anatomic site. Rigorous attention needs to be given to dressing care, and there should be daily assessment of the need for central venous catheters, with prompt removal as soon as is practicable. Healthcare workers should be educated routinely on methods to prevent catheter-related blood stream infections. If rates remain higher than benchmark levels despite proper bedside practice, antiseptic or antibiotic-impregnated catheters can also prevent infections effectively. A recent program utilizing these practices in 103 ICUs in Michigan resulted in a 66% decrease in infection rates.
  
  
  CONCLUSIONS
  There is increasing recognition that a comprehensive strategy to prevent catheter-related blood stream infections can prevent most infections, if not all. This suggests that thousands of infections can potentially be averted if the simple practices outlined herein are followed.
authors.affiliation: Department of Surgery, Washington University School of Medicine, St. Louis, Missouri, USA.
authors.forename: Matthew C
authors.initials: MC
authors.lastname: Byrnes
authors.forename: Craig M
authors.initials: CM
authors.lastname: Coopersmith
mesh_terms: D001769:Blood / Q000276:immunology*; D002404:Catheterization / Q000009:adverse effects*; D006801:Humans; D017053:Infection Control / Q000379:methods*; D014481:United States