title: [Clinical distribution and antibiotic resistance of non-fermentative Gram-negative bacilli infection after liver transplantation].
abstract: OBJECTIVE
  To investigate the epidemiology of non-fermentative Gram-negative bacilli infections after liver transplantation, and to analyze the antibiotic susceptibility to major pathogens.
  
  
  METHODS
  A retrospective survey was conducted to 292 patients who underwent liver transplantation in the period of January 2004 and September 2006. With MicroScan Walkaway- 40 Automatic System, the non-fermentative Gram-negative bacilli infection was analyzed for the identification of pathogens and susceptibility to drugs.
  
  
  RESULTS
  Non-fermentative Gram-negative bacilli infection was identified in 33. 9% of 292 patients after liver transplantation. A total of 99 non-duplicate strains were isolated. The infection was frequently identified from respiratory tract, biliary tract, blood stream and intra-abdominal cavity. The top 3 pathogens were Acinetobacter baumannii, Pseudomonas aeruginosa and Stenotrophomonas maltophilia. Those non-fermentative Gram-negative bacilli were usually resistant to multiple antimicrobial agents.
  
  
  CONCLUSIONS
  The non-fermentative Gram-negative bacilli of postoperative infections in liver transplantation recipients are mostly multi-drug resistant. The microbiological surveillance is important for guiding clinical therapy.
authors.affiliation: Center of Liver Transplantation, West China Hospital, Sichuan University, Chengdu 610041, China.
authors.forename: Jin
authors.initials: J
authors.lastname: Li
authors.forename: Jia-yin
authors.initials: JY
authors.lastname: Yang
authors.forename: Lü-nan
authors.initials: LN
authors.lastname: Yan
authors.forename: Wen-tao
authors.initials: WT
authors.lastname: Wang
authors.forename: Ming-qing
authors.initials: MQ
authors.lastname: Xu
authors.forename: Hong
authors.initials: H
authors.lastname: Wu
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D002648:Child; D002675:Child, Preschool; D024881:Drug Resistance, Bacterial; D005260:Female; D005285:Fermentation; D006090:Gram-Negative Bacteria / Q000187:drug effects* / Q000378:metabolism / Q000502:physiology*; D016905:Gram-Negative Bacterial Infections / Q000188:drug therapy / Q000453:epidemiology*; D006801:Humans; D016031:Liver Transplantation / Q000009:adverse effects; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000188:drug therapy / Q000453:epidemiology*; D055815:Young Adult
chemical_list: D000900:Anti-Bacterial Agents