Palladium-catalyzed selective cross-addition of triisopropylsilylacetylene to internal and terminal unactivated alkynes.
Dinuclear and mononuclear palladium complexes having N,N'-bis[2-(diphenylphosphino)phenyl]amidinate (DPFAM) as a ligand catalyzed the cross-addition of triisopropylsilylacetylene (TIPSA) to unactivated internal alkynes, giving enynes selectively. When palladium catalysts having PPh3, TDMPP, dppe, or dppf were used, dimers of TIPSA were obtained as major products. The reactions of TIPSA with several terminal alkynes also gave cross-adducts selectively, although the yields were moderate.
Tsukada
Naofumi
N
Graduate School of Engineering, Tohoku University, Sendai 980-8579, Japan. tsukada@aporg.che.tohoku.ac.jp
Ninomiya
Satoshi
S
Aoyama
Yoshimi
Y
Inoue
Yoshio
Y