Effect of vagotomy on dynamics of mesenteric lymphatic vessels in the rat.
The functional modulation of lymphatic vessels may be closely associated with intact structures of the vagus nerve. In the present study, the vagotomy was done in Wistar rat to investigate the effect of vagus nerves on dynamic changes of mesenteric lymphatic vessels. After denervation, the mesenteric lymphatics showed significant decreases in contraction rate, diameter in the static state and overall contractile activity under a microscopic observation. The lymphatic contraction rhythm and valve movement became irregular and inconsistent. These findings indicated that the lymphatic innervation might be an important factor for active lymph formation and transportation.
Fang
Yunhai
Y
Department of Anatomy, Shandong University School of Medicine, Jinan 250012, Shandong, PR China.
Ding
Zhaoxi
Z
Bi
Yushun
Y
Gong
Nianming
N
Liu
Yanli
Y
Wei
Luwan
L
Liu
Zhiyu
Z
D000818:Animals; D042601:Lymphatic Vessels / Q000033:anatomy & histology / Q000294:innervation* / Q000502:physiology; D008643:Mesentery / Q000294:innervation* / Q000502:physiology; D009119:Muscle Contraction / Q000502:physiology; D009131:Muscle, Smooth, Vascular / Q000294:innervation / Q000502:physiology; D051381:Rats; D017208:Rats, Wistar; D014628:Vagotomy; D014630:Vagus Nerve / Q000502:physiology* / Q000601:surgery; D014661:Vasoconstriction / Q000502:physiology