Heterotopic parathyroid inclusion in a cervical lymph node.
BACKGROUND
During the pathologic examination of neck dissection specimens, unexpected findings within the lymph nodes may be discovered. Such findings may include benign epithelial inclusions, a second primary tumor, or chronic inflammatory diseases.


METHODS
We report a case of a 59-year-old man who underwent a laryngectomy and bilateral neck dissection for a right transglottic squamous carcinoma of the larynx. During the procedure, a large lymph node measuring 2.5 x 2.2 x 0.8 cm was found at the right level IV.


RESULTS
Histologic examination of the neck dissection specimen revealed benign parathyroid inclusions in the enlarged lymph node. The heterotopic cells expressed parathyroid hormone. This case represents a unique example of heterotopic parathyroid inclusions in a cervical lymph node.


CONCLUSIONS
Parathyroid tissue should be included in the differential diagnosis of cervical intranodal epithelial inclusions.
Veras
Emanuela
E
Department of Pathology and Laboratory Medicine, The University of Texas Medical School at Houston, Texas, USA.
Sturgis
Erich M
EM
Luna
Mario A
MA
D002294:Carcinoma, Squamous Cell / Q000473:pathology / Q000601:surgery; D006801:Humans; D002479:Inclusion Bodies / Q000648:ultrastructure*; D007822:Laryngeal Neoplasms / Q000473:pathology / Q000601:surgery; D007825:Laryngectomy; D008198:Lymph Nodes / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D037981:Neck Dissection; D010280:Parathyroid Glands / Q000648:ultrastructure*