title: Microbial transformation of curcumol by Cunninghamella blakesleana.
abstract: Microbial transformation of curcumol (1) by Cunninghamella blakesleana (AS 3.970) yielded six metabolites. On the basis of spectral data, their structures were elucidated as 14-hydroxy-9E curcumol (2), 10R,14-dihydroxy curcumol (3), 10S,14-epoxy curcumol (4), 10R,14-epoxy curcumol (5), 10S,14-epoxy-7,11-dehydrocurcumol (6), 10R,14-epoxy-7,11-dehydrocurcumol (7), respectively. Among them 2, 3, 6 and 7 are new compounds; 4 and 5, 6 and 7 are two pairs of epimers.
authors.affiliation: Department of Natural Products Chemistry, Shenyang Pharmaceutical University, Shenyang 110016, China.
authors.forename: H
authors.initials: H
authors.lastname: Zhang
authors.forename: F
authors.initials: F
authors.lastname: Qiu
authors.forename: X-S
authors.initials: XS
authors.lastname: Yao
authors.forename: G-X
authors.initials: GX
authors.lastname: Qu
mesh_terms: D001711:Biotransformation; D020093:Cunninghamella / Q000378:metabolism*; D012717:Sesquiterpenes / Q000378:metabolism*
chemical_list: D012717:Sesquiterpenes; C022801:curcumol