title: The differential diagnosis of Axis I psychopathology presenting to a university-based multiple sclerosis clinic.
abstract: Patients carrying a presumptive diagnosis of multiple sclerosis (MS) sometimes present with non-specific clinical signs and symptoms that may be, at least in part, somatic manifestations of psychiatric conditions. This retrospective study was undertaken to identify psychiatric diagnoses among 63 patients whose initial clinical evaluations suggested a primary psychiatric, rather than a primary neurological, etiology for their symptoms. Some 92% of patients met Diagnostic and Statistical Manual of Mental Disorders Fourth Edition Text Revision (DSM-IV-TR) criteria for one or more primary psychiatric disorders, most often including somatoform, mood, and anxiety disorders. Accurate identification and diagnosis of psychiatric conditions producing pseudoneurological or non-specific somatic symptoms is necessary for both treatment and medico-economic reasons.
authors.affiliation: VISN 19 MIRECC (Mental Illness Research Educational Clinical Center), Veteran's Affairs Medical Center, Denver, CO 80220, USA. kristin.brousseau@uchsc.edu
authors.forename: K M
authors.initials: KM
authors.lastname: Brousseau
authors.forename: D B
authors.initials: DB
authors.lastname: Arciniegas
authors.forename: M J
authors.initials: MJ
authors.lastname: Carmosino
authors.forename: J R
authors.initials: JR
authors.lastname: Corboy
mesh_terms: D000328:Adult; D000339:Affect; D000368:Aged; D003937:Diagnosis, Differential; D006801:Humans; D001523:Mental Disorders / Q000175:diagnosis* / Q000209:etiology; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000175:diagnosis* / Q000523:psychology*; D010146:Pain; D012189:Retrospective Studies