title: Pulmonary complications of sickle cell disease in adults.
abstract: Acute and chronic pulmonary complications are a very important cause of morbidity and mortality in sickle cell disease. The Acute Chest Syndrome (ACS) is the most common form of acute pulmonary disease and will be reviewed in this article. Early recognition and aggressive treatment of ACS are important for successful management. The development of pulmonary hypertension is a very important cause of chronic pulmonary disease and contributes to mortality. Because of the increased numbers of sickle cell patients living to adulthood, it is important for primary care providers to become familiar with these complications.
authors.affiliation: University of Missouri-Kansas City and Truman Medical Center, USA. ardilest@umkc.edu
authors.forename: Thomas
authors.initials: T
authors.lastname: Ardiles
authors.forename: Diana
authors.initials: D
authors.lastname: Dark
mesh_terms: D000328:Adult; D000755:Anemia, Sickle Cell / Q000150:complications* / Q000503:physiopathology; D002199:Capillary Permeability / Q000528:radiation effects; D004730:Endothelium, Vascular / Q000503:physiopathology; D017707:Erythrocyte Transfusion; D006801:Humans; D006976:Hypertension, Pulmonary / Q000209:etiology; D008171:Lung Diseases / Q000175:diagnosis / Q000209:etiology*; D011654:Pulmonary Edema / Q000503:physiopathology; D013577:Syndrome