Specific cross-reactivity in sera from cystic echinococcosis patients in an enzyme-linked immunoelectrotransfer blot for cysticercosis diagnostics.
A commercially available enzyme-linked immunoelectrotransfer blot originally intended for diagnosis of cysticercosis was evaluated for echinococcosis diagnosis, because a characteristic band pattern--different from the specific cysticercosis pattern--was observed in sera from patients with echinococcosis. This band pattern was observed in 29 (78%) of 37 parasitologically proven cystic echinococcosis patients. Specificity of these bands was 100% for echinococcosis, when tested with 75 control sera.
van Doorn
H Rogier
HR
Section of Parasitology, Department of Medical Microbiology, Academic Medical Center, Room L1-245, University of Amsterdam, P.O. Box 22660, 1100DD Amsterdam, The Netherlands. h.r.vandoorn@amc.nl
Wentink-Bonnema
Ellen
E
Rentenaar
Rob J
RJ
van Gool
Tom
T
D000947:Antigens, Helminth / Q000097:blood / Q000276:immunology*; D003429:Cross Reactions / Q000276:immunology; D003551:Cysticercosis / Q000175:diagnosis* / Q000276:immunology; D004443:Echinococcosis / Q000175:diagnosis* / Q000276:immunology; D004797:Enzyme-Linked Immunosorbent Assay / Q000379:methods; D006801:Humans
D000947:Antigens, Helminth