[A case of alpha-fetoprotein-producing minute mucosal gastric cancer].
The endoscopic examination of a 63-year-old man revealed a IIc lesion, 5 mm in diameter, in the lesser curvature of the gastric body. His serum alpha-fetoprotein (AFP) level was high at 14.3 ng/ml. Immunohistological studies on the biopsy specimens showed a positive reaction for AFP. Endoscopic ultrasonography revealed that the tumor was limited to the second layer of the gastric wall and this tumor was diagnosed as mucosal cancer. The final diagnosis was AFP-producing mucosal gastric cancer (AFPMGC). Cases of AFPMGC are rarely encountered. The present case suggested that even minute mucosal gastric cancer could produce AFP.
Hirasaki
Shoji
S
Second Department of Internal Medicine, Sumitomo Besshi Hospital.
Kataoka
Junro
J
Nasu
Junichirou
J
Matsubara
Minoru
M
Ikeda
Fusao
F
Suzuki
Seiyuu
S
D000230:Adenocarcinoma / Q000378:metabolism* / Q000473:pathology; D005753:Gastric Mucosa / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D013274:Stomach Neoplasms / Q000378:metabolism* / Q000473:pathology; D000509:alpha-Fetoproteins / Q000096:biosynthesis*
D000509:alpha-Fetoproteins