title: [Hypertrophic pachymeningitis, glomerulonephritis and P-ANCA associated small vessel vasculitis].
abstract: Hypertrophic pachymeningitis is a very unusual disease, the main characteristic of which is thickening of the dura mater. We describe a patient who started this illness showing chronic headache and pauciimmune necrotizing extracapillary perinuclear antineutrophil cytoplasmic antibody (P-ANCA) associated glomerulonephritis. The diagnosis was made by brain magnetic resonance image. She received immunosuppressant therapy with prednisonel and cyclophosphamide with clinical improvement.
authors.affiliation: 5 Cátedra, Departamento de Medicina, Hospital de Clínicas José de San Martin, Facultad de Medicina, Universidad de Buenos Aires. omazzocchi@uolsinectis.com.ar
authors.forename: Octavio
authors.initials: O
authors.lastname: Mazzocchi
authors.forename: Jorge A
authors.initials: JA
authors.lastname: Risso
authors.forename: Florencia
authors.initials: F
authors.lastname: Viozzi
authors.forename: Natalia P
authors.initials: NP
authors.lastname: Apa
authors.forename: Marina C
authors.initials: MC
authors.lastname: Peralba
authors.forename: Miguel A
authors.initials: MA
authors.lastname: Nadal
authors.forename: Graciela E
authors.initials: GE
authors.lastname: De Rosa
mesh_terms: D000328:Adult; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D019268:Antibodies, Antineutrophil Cytoplasmic / Q000097:blood*; D003520:Cyclophosphamide / Q000627:therapeutic use; D005260:Female; D005921:Glomerulonephritis / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D006261:Headache / Q000209:etiology; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008279:Magnetic Resonance Imaging; D008581:Meningitis / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D011239:Prednisolone / Q000627:therapeutic use; D014657:Vasculitis / Q000150:complications* / Q000188:drug therapy / Q000276:immunology
chemical_list: D000893:Anti-Inflammatory Agents; D019268:Antibodies, Antineutrophil Cytoplasmic; D007166:Immunosuppressive Agents; D003520:Cyclophosphamide; D011239:Prednisolone