Real-time functional brain mapping using electrocorticography.
We demonstrate the feasibility of real-time cortical mapping from arrays of subdural electrodes using the electrocorticographic signal power in the higher spectral frequencies (76-200 Hz, or "chi-index"). Hand area was mapped offline in eight individuals using brief baseline and hand-movement measurements. In one patient, hand sensorimotor cortex was identified online during a handshake. We propose that this high-frequency component of the electrocorticogram provides a generic, reliable, clinically useful correlate of local cortical function.
Miller
Kai J
KJ
University of Washington, Department of Physics, Box 351560, Seattle, WA 98195-1560, USA. kjmiller@gmail.com
denNijs
Marcel
M
Shenoy
Pradeep
P
Miller
John W
JW
Rao
Rajesh P N
RP
Ojemann
Jeffrey G
JG
D000293:Adolescent; D000328:Adult; D001921:Brain / Q000502:physiology*; D001931:Brain Mapping / Q000379:methods*; D004569:Electroencephalography / Q000379:methods*; D005260:Female; D006225:Hand / Q000294:innervation; D006801:Humans; D008297:Male; D008875:Middle Aged; D009048:Motor Skills / Q000502:physiology