Tick acquisition of Ehrlichia canis from dogs treated with doxycycline hyclate.
Doxycycline generally alleviates clinical monocytic ehrlichiosis, but its efficacy in the control of monocytotropic ehrlichial pathogens requires further investigation. In this study, Ehrlichia canis was detected in dogs treated with doxycycline for 14 days and in ticks fed on these dogs, suggesting that treated dogs can remain reservoirs for E. canis.
Schaefer
John J
JJ
Department of Veterinary Preventive Medicine, The Ohio State University, Columbus, Ohio 43210, USA.
Needham
Glen R
GR
Bremer
William G
WG
Rikihisa
Yasuko
Y
Ewing
S A
SA
Stich
R W
RW
D000818:Animals; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D001096:Arachnid Vectors; D004283:Dog Diseases / Q000188:drug therapy* / Q000382:microbiology; D004285:Dogs; D004318:Doxycycline / Q000031:analogs & derivatives* / Q000627:therapeutic use; D041061:Ehrlichia canis; D016873:Ehrlichiosis / Q000188:drug therapy* / Q000382:microbiology / Q000662:veterinary*; D020133:Reverse Transcriptase Polymerase Chain Reaction; D048508:Rhipicephalus sanguineus / Q000254:growth & development / Q000382:microbiology*
D000900:Anti-Bacterial Agents; D004318:Doxycycline