title: Immunochromatographic strip test for rapid detection of nevirapine in plasma samples from human immunodeficiency virus-infected patients.
abstract: We report a novel one-step immunochromatographic strip test for the rapid, qualitative detection of nevirapine in plasma samples from human immunodeficiency virus-infected patients. The sensitivity was 100% (95% confidence interval [95% CI], 97.8 to 100%), and the specificity was 99.5% (95% CI, 97.2 to 99.9%). The limit of detection was 25 ng/ml. Immunochromatographic strip tests are simple, rapid, and cheap assays that could greatly facilitate drug level monitoring in resource-limited settings.
authors.affiliation: Harvard School of Public Health, Harvard University, Boston, MA, USA.
authors.forename: Tim R
authors.initials: TR
authors.lastname: Cressey
authors.forename: Sawitree
authors.initials: S
authors.lastname: Nangola
authors.forename: Yardpiroon
authors.initials: Y
authors.lastname: Tawon
authors.forename: Mookda
authors.initials: M
authors.lastname: Pattarawarapan
authors.forename: Marc
authors.initials: M
authors.lastname: Lallemant
authors.forename: Chatchai
authors.initials: C
authors.lastname: Tayapiwatana
mesh_terms: D000328:Adult; D019380:Anti-HIV Agents / Q000097:blood*; D002845:Chromatography; D002851:Chromatography, High Pressure Liquid; D016903:Drug Monitoring / Q000191:economics / Q000379:methods; D005260:Female; D015658:HIV Infections / Q000097:blood*; D006801:Humans; D007120:Immunochemistry; D019829:Nevirapine / Q000097:blood*
chemical_list: D019380:Anti-HIV Agents; D019829:Nevirapine