title: Anti-anxiety effect of ovary lipid extracted from Skipjack tuna (Katsuwonus pelamis) in rats.
abstract: Using an elevated plus-maze test, we evaluated anxiety level in rats given ovary lipid extracted from Skipjack tuna (Katsuwonus pelamis; OLS). The percentage of open time was significantly higher in rats given OLS than in rats in the control group, but lower than in rats given diazepam (1.0 mg/kg body weight). Based on this fact and findings about other indicators, this study showed that OLS does not have as fast-acting and strong an anti-anxiety effect as diazepam but that continuous ingestion of OLS causes an anti-anxiety effect in animals.
authors.affiliation: Industrial Research Institute of Shizuoka Prefecture, Aoi, Shizuoka, Japan.
authors.forename: Katumasa
authors.initials: K
authors.lastname: Ookawa
authors.forename: Kazuo
authors.initials: K
authors.lastname: Mochizuki
authors.forename: Eiji
authors.initials: E
authors.lastname: Shida
authors.forename: Toshihiro
authors.initials: T
authors.lastname: Suzuki
authors.forename: Toshihiro
authors.initials: T
authors.lastname: Suzuki
authors.forename: Tomoko
authors.initials: T
authors.lastname: Ooba
authors.forename: Toru
authors.initials: T
authors.lastname: Matumoto
authors.forename: Yoshinori
authors.initials: Y
authors.lastname: Hokari
authors.forename: Masayuki
authors.initials: M
authors.lastname: Hashidume
authors.forename: Hidehiko
authors.initials: H
authors.lastname: Yokogoshi
mesh_terms: D000818:Animals; D014151:Anti-Anxiety Agents / Q000302:isolation & purification* / Q000627:therapeutic use*; D001007:Anxiety / Q000188:drug therapy*; D003975:Diazepam / Q000627:therapeutic use; D005260:Female; D008055:Lipids / Q000627:therapeutic use*; D010053:Ovary / Q000737:chemistry*; D051381:Rats; D013997:Time Factors; D014413:Tuna
chemical_list: D014151:Anti-Anxiety Agents; D008055:Lipids; D003975:Diazepam