title: Complex partial status epilepticus as a manifestation of Hashimoto's encephalopathy.
abstract: Epileptic seizures are a frequent manifestation of Hashimoto's encephalopathy. However, status epilepticus associated with Hashimoto's encephalopathy are not well characterized in medical literature. We described here a 16-year-old girl who presented with complex partial status epilepticus associated with elevated anti-thyroid antibodies. Ictal EEG showed lateralized high amplitude rhythmic delta waves over the right hemisphere and ictal single-photon emission computed tomography revealed regional hyperperfusion of the right parietal and temporal lobes. The patient was unresponsive to antiepileptic drug therapy but responded to intravenous steroid treatment. Screening of serum anti-thyroid antibodies for unexplained encephalopathy with epileptic seizures is suggested, as early recognition and prompt steroid treatment may lead to a favorable prognosis.
authors.affiliation: Department of Neurology, Chang Gung Memorial Hospital, Kaohsiung Medical Center, Chang Gung University College of Medicine, Kaohsiung 833, Taiwan.
authors.forename: Meng-Han
authors.initials: MH
authors.lastname: Tsai
authors.forename: Lien-Hui
authors.initials: LH
authors.lastname: Lee
authors.forename: Shan-Der
authors.initials: SD
authors.lastname: Chen
authors.forename: Cheng-Hisen
authors.initials: CH
authors.lastname: Lu
authors.forename: Ming-Tsung
authors.initials: MT
authors.lastname: Chen
authors.forename: Yao-Chung
authors.initials: YC
authors.lastname: Chuang
mesh_terms: D000293:Adolescent; D004569:Electroencephalography / Q000379:methods; D004660:Encephalitis / Q000150:complications* / Q000175:diagnosis; D005260:Female; D006801:Humans; D013226:Status Epilepticus / Q000150:complications* / Q000175:diagnosis; D013967:Thyroiditis, Autoimmune / Q000150:complications* / Q000175:diagnosis; D015899:Tomography, Emission-Computed, Single-Photon / Q000379:methods