title: MR-guided vacuum-assisted breast biopsy with a handheld biopsy system: clinical experience and results in postinterventional MR mammography after 24 h.
abstract: This prospective study evaluates the feasibility of the magnetic resonance (MR)-guided vacuum-assisted breast biopsy with a handheld vacuum-biopsy system and documents the biopsy results with MR mammography 24 h after the procedure. MR-guided biopsy was undertaken in 33 patients with 34 lesions on dynamic MR mammography. The interventions were performed with the handheld 10-gauge Vacora vacuum-biopsy system. In all cases, dynamic MR mammography was performed 24 h after the procedure to determine the extent of the lesion removal and to identify the lesions that were missed. In 5/34 (14.7%) lesions, biopsy was not performed because no suspicious lesion was identified on the day of biopsy. In 25/29 (86.2%) lesions, the biopsy was successfully performed with a complete removal in 4/29 (13.8%) and a partial removal of 21/29 (72.4%) lesions. In 4/29 (13.8%) interventions the lesion was missed with the biopsy. In one case, histopathology after surgical excision revealed ductal carcinoma in situ. Histopathology revealed 9/29 (31%) malignant and 20/29 (68.9%) benign lesions. MR-guided vacuum-assisted breast biopsy with the handheld Vacora vacuum-biopsy system is technically feasible in most cases. MR mammography 24 h after the biopsy should be performed in those cases in which the biopsy success is unclear immediately after the procedure.
authors.affiliation: Department of Diagnostic and Interventional, Radiology and Neuroradiology, University Hospital Essen, Hufelandstr. 55, 45122 Essen, Germany. elke.hauth@uk-essen.de
authors.forename: E A
authors.initials: EA
authors.lastname: Hauth
authors.forename: H J
authors.initials: HJ
authors.lastname: Jaeger
authors.forename: J
authors.initials: J
authors.lastname: Lubnau
authors.forename: S
authors.initials: S
authors.lastname: Maderwald
authors.forename: F
authors.initials: F
authors.lastname: Otterbach
authors.forename: R
authors.initials: R
authors.lastname: Kimmig
authors.forename: M
authors.initials: M
authors.lastname: Forsting
mesh_terms: D000328:Adult; D000368:Aged; D001706:Biopsy / Q000295:instrumentation*; D001943:Breast Neoplasms / Q000473:pathology*; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted; D053783:Magnetic Resonance Imaging, Interventional / Q000379:methods*; D008875:Middle Aged; D011446:Prospective Studies; D013997:Time Factors; D014618:Vacuum