title: Surgical management of stress urinary incontinence.
abstract: BACKGROUND
  This review evaluates the most recent knowledge regarding surgical management of stress urinary incontinence.
  
  
  METHODS
  A comprehensive MEDLINE search was performed, limited to those articles published from 1995 to 2005. In total, 470 articles were reviewed-the most relevant of which were considered, and additional ones were selected by reviewing these studies' bibliographies. Overall, 53 articles were selected and used in this study.
  
  
  RESULTS
  Few randomized controlled trials have been performed. The best results of retropubic procedures are seen when the intrinsic urethral sphincter is competent and its effectiveness is sustained in the long term. A laparoscopic approach, although less popular and with a lower short-term cure rate, is an alternative. Sling surgeries can be the first-line treatment for all types of stress urinary incontinence. Autologous grafts are still considered the gold standard, but synthetic materials such as tension-free tape have comparable results with standard open retropubic procedures. Still, long-term cure and complication rates have not yet been elucidated. Using urethral bulking agents is the least invasive approach, applicable in both intrinsic sphincter deficiency and urethral hypermobility. However, it has a poor long-term outcome and necessitates repeat injections.
  
  
  CONCLUSIONS
  Long-term data suggest that Burch colposuspension and sling procedures produce similar objective cure rates. New synthetic suburethral slings such as tension-free vaginal tape have gained popularity in recent years. Complications of traditional and newer suburethral slings are declining but still occur and often are associated with serious morbidity. New therapies must be studied in randomized clinical trials.
authors.affiliation: Department of Urology, Shaheed Labbafinejad Hospital, Shaheed Beheshti University of Medical Sciences, Tehran, Iran. fsharifiaghdas@yahoo.com
authors.forename: Farzaneh
authors.initials: F
authors.lastname: Sharifi-Aghdas