Trousseau syndrome due to pleural mesothelioma.
BACKGROUND
Thrombosis involving a brain infarction frequently occurs in patients with a malignant tumor. Although nearly all types of tumor have been reported in association with a hypercoagulable state, pleural mesothelioma-associated Trousseau syndrome is extremely rare.


CONCLUSIONS
A 69-year-old female was admitted to our hospital with cough, sputum, and breathing difficulties. She was diagnosed as having a mesothelioma from a percutaneous pleural biopsy. Although there were no risk factors for atherosclerosis, brain infarctions showed frequent relapses, even under anticoagulant therapy, and there was a marked hypercoagulable state.


CONCLUSIONS
Attention should be paid to this syndrome when unexplained brain infarctions occur in patients with pleural mesothelioma.
Matsui
Hideaki
H
Department of Neurology, Sumitomo Hospital, Osaka, Japan. matsui-hideaki@sumitomo-hp.or.jp
Nishinaka
Kazuto
K
Oda
Masaya
M
Kubori
Tamotsu
T
Udaka
Fukashi
F
D000368:Aged; D020520:Brain Infarction; D018450:Disease Progression; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D008654:Mesothelioma / Q000150:complications*; D010997:Pleural Neoplasms / Q000150:complications*; D020246:Venous Thrombosis / Q000209:etiology* / Q000473:pathology