title: Poly(3,4-ethylenedioxythiophene-co-(5-amino-2-naphthalenesulfonic acid)) (PEDOT-PANS) film modified glassy carbon electrode for selective detection of dopamine in the presence of ascorbic acid and uric acid.
abstract: Poly(3,4-ethylenedioxythiophene-co-(5-amino-2-naphthalenesulfonic acid)) (PEDOT-PANS) film modified glassy carbon electrode was prepared by electrochemical polymerization technique. The properties of modified electrode was studied. It was found that the electrochemical properties of modified electrode was very much dependent on the experimental conditions, such as monomer oxidation potential and pH. The modified electrode surface was characterized by scanning electron microscopy (SEM). The PEDOT-PANS film modified electrode shows electrocatalytic activity toward oxidation of dopamine (DA) in acetate buffer solution (pH 5.0) and results in a marked enhancement of the current response. The linear sweep voltammetric (LSV) peak heights are linear with DA concentration from 2x10(-6) to 1x10(-5) M. The detection limit is 5x10(-7) M. More over, the interferences of ascorbic acid (AA) and uric acid (UA) were effectively diminished. This work provides a simple and easy approach for selective determination of dopamine in the presence of ascorbic acid and uric acid.
authors.affiliation: Electroanalysis and Bioelectrochemistry Lab, Department of Chemical Engineering and Biotechnology, National Taipei University of Technology, No. 1, Section 3, Chung-Hsiao East Road, Taipei 106, Taiwan, ROC.
authors.forename: A
authors.initials: A
authors.lastname: Balamurugan
authors.forename: Shen-Ming
authors.initials: SM
authors.lastname: Chen
mesh_terms: D001205:Ascorbic Acid / Q000032:analysis; D002244:Carbon / Q000737:chemistry; D002384:Catalysis; D004298:Dopamine / Q000032:analysis*; D004566:Electrodes; D005898:Glass / Q000737:chemistry; D009282:Naphthalenesulfonates / Q000737:chemistry*; D010084:Oxidation-Reduction; D011199:Potentiometry / Q000379:methods*; D012680:Sensitivity and Specificity; D013876:Thiophenes / Q000737:chemistry*; D014527:Uric Acid / Q000032:analysis
chemical_list: D009282:Naphthalenesulfonates; D013876:Thiophenes; C522429:poly(3,4-ethylenedioxythiophene-co-(5-amino-2-naphthalenesulfonic acid)); D014527:Uric Acid; D002244:Carbon; D001205:Ascorbic Acid; D004298:Dopamine