Unusual bronchopulmonary foregut malformation associated with pericardial defect: bronchogenic cyst communicating with tubular esophageal duplication.
We report a case of unusual bronchopulmonary foregut malformation composed of a mediastinal bronchogenic cyst with sequestrated lung tissue and communicating tubular esophageal duplication associated with complete pericardial defect. A 18-yr. old man, who had suffered from dry cough and mild dyspnea, was admitted because of an incidentally detected chest mass. A computed tomography scan demonstrated a cystic mass with an air fluid level connected with esophagus in the middle mediastinum. The surgically resected mass was a pleural invested accessory lobe of the lung (8.0 x 7.0 x 4.5 cm) connected with the esophageal wall by a tubular structure (3.0 cm in length and 2.0 cm in diameter). A complete left pericardial defect was also identified. Histologically, the cystic wall was composed of fibrovascular connective tissue with a smooth muscle layer, mixed seromucous glands and cartilage, and the inner surface of the cyst was lined by ciliated pseudostratified columnar epithelium. The inner surface of the tubular structure was lined by non-keratinizing or keratinizing squamous epithelium, and the wall contained submucosal mucous glands, muscularis mucosa, and duplicated muscularis propria. This case is important in understanding the embryological pathogenesis of the variable spectrum of the bronchopulmonary foregut malformation.
Eom
Dae-Woon
DW
Departments of Pathology, University of Ulsan College of Medicine, Gangneung Asan Hospital, 415 Bandong-ri, Sacheon-myeon, Gangneung, Korea. edwjyh@gnah.co.kr
Kang
Gil Hyun
GH
Kim
Jong Wook
JW
Ryu
Dae Shick
DS
D000293:Adolescent; D001994:Bronchogenic Cyst / Q000150:complications* / Q000175:diagnosis*; D004064:Digestive System / Q000473:pathology; D004934:Esophageal Cyst / Q000175:diagnosis / Q000473:pathology; D004935:Esophageal Diseases / Q000150:complications* / Q000175:diagnosis*; D004947:Esophagus / Q000002:abnormalities / Q000473:pathology*; D006801:Humans; D008168:Lung / Q000002:abnormalities / Q000473:pathology; D008297:Male; D010496:Pericardium / Q000473:pathology; D014057:Tomography, X-Ray Computed