title: Isolation of steroidal glycosides from Solanum xanthocarpum and studies on their antifungal activities.
abstract: Isolation of the methanol extract of Solanum xanthocarpum resulted in the isolation and characterization of carpesterol (1) and four steroidal glycosides (2, 3, 4, and 5). The structures of these compounds were established by spectroscopic analysis. The antifungal activity of the steroidal compounds extracted from the fruits of S. xanthocarpum was investigated against Aspergillus niger and Trichoderma viride. The isolated compounds 1, 2, 3, 4, and 5 exhibited inhibitory effects on the radial growth of A. niger and Trichoderma viride.
authors.affiliation: Department of Chemistry, Manipur University, Canchipur 795003, India. ok_mukherjee@yahoo.co.in
authors.forename: Okram M
authors.initials: OM
authors.lastname: Singh
authors.forename: K
authors.initials: K
authors.lastname: Subharani
authors.forename: N I
authors.initials: NI
authors.lastname: Singh
authors.forename: N Babita
authors.initials: NB
authors.lastname: Devi
authors.forename: L
authors.initials: L
authors.lastname: Nevidita
mesh_terms: D000935:Antifungal Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D001234:Aspergillus niger / Q000187:drug effects; D005638:Fruit / Q000737:chemistry; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D019906:Nuclear Magnetic Resonance, Biomolecular; D009904:Optical Rotation; D010840:Phytosterols / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D010946:Plants, Medicinal / Q000737:chemistry; D032322:Solanum / Q000737:chemistry*; D021241:Spectrometry, Mass, Electrospray Ionization; D013055:Spectrophotometry, Infrared; D014242:Trichoderma / Q000187:drug effects
chemical_list: D000935:Antifungal Agents; D006027:Glycosides; D010840:Phytosterols