title: Optical coherence tomography and multifocal electroretinogram findings in chronic solar retinopathy.
abstract: OBJECTIVE
  To correlate the structural and functional retinal defects, which are induced photochemically in chronic solar retinopathy.
  
  
  METHODS
  Observational case report.
  
  
  METHODS
  Four emmetropic eyes of two patients, previously diagnosed with chronic solar retinopathy, were evaluated by optical coherence tomography (OCT), multifocal electroretinography, and fluorescein angiography.
  
  
  RESULTS
  Visual acuity ranged from 20/80 to 20/50 and all subjects had central and steady fixation. In all eyes, OCT demonstrated a hyporeflective space at the level of outer retinal and retinal pigment epithelium (RPE) layers, which was limited to the fovea. The foveal contour was preserved with normal vitreoretinal interface. Multifocal electroretinogram (mfERG) trace array of the first-order kernel demonstrated attenuated responses extending to a larger area, the para- and perifovea. A foveal RPE window defect was angiographically evident in all cases.
  
  
  CONCLUSIONS
  A model of centrifugal neuronal damage is proposed for chronic solar retinopathy, with more functional than structural neuroretinal defects.
authors.affiliation: Division of Ophthalmology, Department of Clinical Neurosciences, University Hospitals of Geneva, Geneva, Switzerland.
authors.forename: Alexandros N
authors.initials: AN
authors.lastname: Stangos
authors.forename: Ioannis K
authors.initials: IK
authors.lastname: Petropoulos
authors.forename: Jean-Antoine C
authors.initials: JA
authors.lastname: Pournaras
authors.forename: Marc
authors.initials: M
authors.lastname: Zaninetti
authors.forename: François-Xavier
authors.initials: FX
authors.lastname: Borruat
authors.forename: Constantin J
authors.initials: CJ
authors.lastname: Pournaras
mesh_terms: D002908:Chronic Disease; D004596:Electroretinography; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D008875:Middle Aged; D011832:Radiation Injuries / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology*; D012160:Retina / Q000503:physiopathology / Q000528:radiation effects*; D012164:Retinal Diseases / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology*; D013472:Sunlight / Q000009:adverse effects*; D041623:Tomography, Optical Coherence; D014792:Visual Acuity