title: Brain abscess caused by paradoxical embolization in Ebstein's anomaly.
abstract: A 25-year-old woman presented with Streptococcus milleri brain abscess. Previous cardiac history was unremarkable. In search for a source of embolism echocardiography was performed and revealed a previous undiagnosed Ebstein's anomaly of moderate severity with apical displacement of the septal leaflet of the tricuspid valve and a secundum atrial septal defect (ASD) with left to right shunt. The combination of increased right atrial pressure caused by Ebstein's and an ASD with possibility of transient right to left shunt predispose for paradoxical embolization. The most likely reason for development of a brain abscess in this patient is septic embolization from an infectious focus outside the heart. Ebstein's anomaly can remain undiagnosed until adulthood if the right ventricle, in spite of the smaller size, is haemodynamically well functioning.
authors.affiliation: Department of Heart Disease, Haukeland University Hospital, 5021 Bergen, Norway. mai.tone.lonnebakken@helse-bergen.no
authors.forename: M T
authors.initials: MT
authors.lastname: Lønnebakken
authors.forename: G
authors.initials: G
authors.lastname: Greve
authors.forename: E
authors.initials: E
authors.lastname: Leirgul
authors.forename: E
authors.initials: E
authors.lastname: Gerdts
mesh_terms: D000328:Adult; D001922:Brain Abscess / Q000382:microbiology*; D004437:Ebstein Anomaly / Q000150:complications* / Q000000981:diagnostic imaging; D004452:Echocardiography; D019320:Embolism, Paradoxical / Q000382:microbiology*; D005260:Female; D006344:Heart Septal Defects, Atrial / Q000150:complications* / Q000000981:diagnostic imaging; D006801:Humans; D013290:Streptococcal Infections / Q000150:complications*; D034364:Streptococcus milleri Group