title: Yolk sac tumor of the vagina.
abstract: Malignant germ-cell tumors GCT are rare tumors of childhood accounting for less than 3% of pediatric malignancies. Endodermal sinus tumors EST form the most common histologic subtype of malignant GCT. The vagina is an extremely rare site for GCTs. An 8-month-old female was admitted with a short history of vaginal bleeding, and a mass protruding from the vagina. A mass was palpable anteriorly on rectal examination. Computed tomography showed a tumor mass posterior to the bladder. A biopsy revealed a vaginal EST. The serum alpha-fetoprotein was elevated. Vaginohysterectomy was carried out. She was subsequently referred to the oncologist for further management.
authors.affiliation: Department of Pathology, Alzahra Hospital, Isfahan University of Medical Sciences, Isfahan, Iran.
authors.forename: Parvin
authors.initials: P
authors.lastname: Mahzouni
authors.forename: Shervin
authors.initials: S
authors.lastname: Pejhan
authors.forename: Mahmoud
authors.initials: M
authors.lastname: Ashrafi
mesh_terms: D018240:Endodermal Sinus Tumor / Q000473:pathology*; D005260:Female; D006801:Humans; D007223:Infant; D014625:Vaginal Neoplasms / Q000473:pathology*