[Using synthetic analogues of somatostatin in the complex treatment of bleedings from varicose esophagus and stomach veins in patients with liver cirrhosis].
Bleedings from varicose veins of the esophagus and stomach belong to the most serious complications of hepatic cirrhosis and 30% of such patients suffer from them. The article features a review of the literature on the application of somatostatin synthetic analogues in a complex treatment of bleedings from varicose esophagus and stomach veins. Hemostasis can be achieved in 84% of patients by means of ocreatide monotherapy. Hemostasis becomes efficient in 97% of cases when ocreatide is used in a complex therapy with ligation.
Vasnev
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Kozlov
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D004359:Drug Therapy, Combination; D004947:Esophagus / Q000098:blood supply*; D006470:Hemorrhage / Q000188:drug therapy* / Q000209:etiology; D006801:Humans; D008103:Liver Cirrhosis / Q000150:complications*; D015282:Octreotide / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D013004:Somatostatin / Q000031:analogs & derivatives*; D013270:Stomach / Q000098:blood supply*; D014648:Varicose Veins / Q000150:complications*; D014662:Vasoconstrictor Agents / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*
D014662:Vasoconstrictor Agents; D013004:Somatostatin; D015282:Octreotide