title: Magnesium as a preventive treatment for paediatric episodic tension-type headache: results at 1-year follow-up.
abstract: The objective was to confirm the long-term utility of magnesium salts treatment on a group of young patients suffering from episodic tension-type headache (ETTH). The study was carried out at the Outpatient Headache Center at the National Neurological Institute "C. Besta," Milan, Italy, with 45 children/adolescents with ETTH reporting consecutively for treatment. Magnesium pidolate (2.25 g) was given twice per day for three months. Medication was not administered during the year of follow-up. No other treatment was provided at any time. Patients showed significant symptom reduction. Headache days decreased by 69.9%, whereas analgesics consumption was reduced by 65.4%. Overall disability levels improved by the greatest percent - 75.7%. MIDAS subscores improved as well (question A=58.0%; question B=22.5%). Although uncontrolled, these findings are encouraging and suggest that further, better controlled research investigations are warranted.
authors.affiliation: Headache Center, National Neurological Institute C. Besta, Via Celoria 11, I-20133, Milan, Italy. liciagrazzi@mac.com
authors.forename: L
authors.initials: L
authors.lastname: Grazzi
authors.forename: F
authors.initials: F
authors.lastname: Andrasik
authors.forename: S
authors.initials: S
authors.lastname: Usai
authors.forename: G
authors.initials: G
authors.lastname: Bussone
mesh_terms: D000293:Adolescent; D002648:Child; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007558:Italy; D008297:Male; D011761:Pyrrolidonecarboxylic Acid / Q000627:therapeutic use*; D018781:Tension-Type Headache / Q000517:prevention & control*; D016896:Treatment Outcome
chemical_list: D011761:Pyrrolidonecarboxylic Acid