title: Postterm closure of the cavum septi pellucidi and developmental outcome in premature infants.
abstract: The authors report the natural history of closure of the cavum Septi pellucidi in premature infants 26 to 27 weeks postconception at birth and compare the developmental outcome in these infants who had closure by 42 weeks postconception to those who still had a cavum septum pellucidi visualized on ultrasound at approximately term (35-42 weeks). Of 72 patients, 35 patients still had a cavum septum pellucidi visualized on the last ultrasound done between 35 and 42 weeks postconception, and the developmental outcome of these patients was no different from those with earlier closure. The authors conclude that persistence of a cavum septi pellucidi through term is not an independent risk factor for developmental delay.
authors.affiliation: Munroe-Meyer Institute for Genetics and Rehabilitation, University of Nebraska Medical Center, Omaha, NE 68198-5440, USA. hneedelm@unmc.edu
authors.forename: Howard
authors.initials: H
authors.lastname: Needelman
authors.forename: Bruce
authors.initials: B
authors.lastname: Schroeder
authors.forename: Matthew
authors.initials: M
authors.lastname: Sweeney
authors.forename: John
authors.initials: J
authors.lastname: Schmidt
authors.forename: John B
authors.initials: JB
authors.lastname: Bodensteiner
authors.forename: G B
authors.initials: GB
authors.lastname: Schaefer
mesh_terms: D002552:Cerebral Ventricles / Q000254:growth & development*; D002657:Child Development; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007234:Infant, Premature / Q000254:growth & development*; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D012688:Septum Pellucidum / Q000254:growth & development*; D014057:Tomography, X-Ray Computed / Q000379:methods