Diagnosis of Chiari III malformation by second trimester fetal MRI with postnatal MRI and CT correlation.
We report a case of Chiari III malformation diagnosed by fetal MRI. Ultrasound (US) performed at a gestational age of 18 weeks demonstrated a posterior skull base cyst. Repeat US at 19 weeks demonstrated neural tissue in the cyst, consistent with an encephalocele. MR imaging at 23 weeks confirmed the presence of an occipital encephalocele, demonstrated additional bony defect in the upper cervical spine, and identified abnormal morphology and position of the brainstem consistent with the diagnosis of Chiari III. Postnatal MRI and CT confirmed the fetal MRI findings and demonstrate the utility of fetal MRI in the early evaluation of songraphically detected posterior fossa abnormalities.
Smith
Alice B
AB
Department of Radiology, University of California, San Francisco, San Francisco, CA, USA. absmith@pobox.com
Gupta
Nalin
N
Otto
Carl
C
Glenn
Orit A
OA
D000328:Adult; D001139:Arnold-Chiari Malformation / Q000175:diagnosis*; D003937:Diagnosis, Differential; D005260:Female; D005333:Fetus / Q000000981:diagnostic imaging* / Q000473:pathology*; D006801:Humans; D007231:Infant, Newborn; D008279:Magnetic Resonance Imaging; D011247:Pregnancy; D011262:Pregnancy Trimester, Second; D013223:Statistics as Topic; D014057:Tomography, X-Ray Computed