Strategy for encoding and comparison of gene expression signatures.
EXALT (EXpression signature AnaLysis Tool) is a computational system enabling comparisons of microarray data across experimental platforms and different laboratories http://seq.mc.vanderbilt.edu/exalt/. An essential feature of EXALT is a database holding thousands of gene expression signatures extracted from the Gene Expression Omnibus, and encoded in a searchable format. This novel approach to performing global comparisons of shared microarray data may have enormous value when coupled directly with a shared data repository.
Yi
Yajun
Y
Department of Medicine, Vanderbilt University, Nashville, Tennessee 37232-0275, USA.
Li
Chun
C
Miller
Clay
C
George
Alfred L
AL
D000818:Animals; D045744:Cell Line, Tumor; D019295:Computational Biology / Q000379:methods*; D020869:Gene Expression Profiling / Q000379:methods*; D006801:Humans; D012984:Software