[Postoperative safety of liver donors with positive anti-hepatitis B core antibodies for adult to adult living donor liver transplantation].
OBJECTIVE
To evaluate the safety of liver donors with positive anti-HBc for adult to adult living-donor liver transplantation.


METHODS
Between March 2003 and July 2005, 52 donors underwent hepatectomy for living-donor liver transplantation at the West China Hospital. Among them, four were anti-HBc-positive, 48 were anti-HBc-negative. The perioperative clinical profiles of the two groups were compared which included the Hepatitis B indicators, liver functions and growth of liver after operation.


RESULTS
No significant differences were found between the two groups of donors in liver function, hepatitis B indicators, comorbidity, regeneration of remnant livers, and length of stay in hospitals.


CONCLUSIONS
Anti-HBc-positive donors do not have higher risks than anti-HBc-negative donors for liver transplantation.
Yang
Jia-yin
JY
Center for Liver Transplantation, West China Hospital, Sichuan University, Chengdu 610041, China.
Yan
Lü-nan
LN
Li
Bo
B
Zeng
Yong
Y
Wen
Tian-fu
TF
Zhao
Ji-chun
JC
Wang
Wen-tao
WT
Xu
Ming-qing
MQ
Ma
Yu-kui
YK
Chen
Zhe-yu
ZY
Wu
Hong
H
D000328:Adult; D000368:Aged; D015415:Biomarkers / Q000378:metabolism; D005260:Female; D006510:Hepatitis B Antibodies / Q000276:immunology / Q000378:metabolism*; D006515:Hepatitis B virus / Q000276:immunology*; D006801:Humans; D008099:Liver / Q000378:metabolism / Q000502:physiology / Q000821:virology; D016031:Liver Transplantation; D019520:Living Donors; D008297:Male; D008875:Middle Aged; D011184:Postoperative Period; D012449:Safety; D055815:Young Adult
D015415:Biomarkers; D006510:Hepatitis B Antibodies