Pleuropulmonary blastoma: transition from type I (cystic) to type III (solid).
Pleuropulmonary blastoma is a unique dysontogenetic neoplasm of childhood that appears as a pulmonary and/or pleural-based mass, and is characterised histologically by a primitive, variably mixed blastematic and sarcomatous appearance. We report a 12-month-old female child who was operated for a lung cyst at the age of six months and postoperative histopathology was suggestive of type I pleuropulmonary blastoma (PPB). She presented to us at the age of twelve months with a huge mass over the left chest wall and axilla, histopathological examination of which was type III PPB. Partial removal of the lung cyst led to transition from type I to type III PPB in a short span of a few months. Complete surgical removal followed by adjuvant chemotherapy is needed for a better outcome in type I PPB.
Shivastava
R
R
Department of Radiotherapy, Mahatma Gandhi Institute of Medical Sciences, Sevagram, Wardha 442102, Maharashtra, India. drabhijeetsaha@yahoo.com
Saha
A
A
Mehera
B
B
Batra
P
P
Gagane
N M
NM
D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007223:Infant; D008175:Lung Neoplasms / Q000145:classification / Q000473:pathology* / Q000601:surgery; D018202:Pulmonary Blastoma / Q000145:classification / Q000473:pathology* / Q000601:surgery