title: Electrocardiographic abnormalities associated with poisoning.
abstract: This article will review the cardiovascular toxicities of various medications, stressing the electrocardiographic presentation--both rhythm and morphological issues--and emphasizing recognition and management issues. Cardiovascular toxins are grouped into categories causing similar electrocardiographic effects, including the potassium efflux blockers, sodium channel blockers, sodium-potassium adenosine triphosphatase blockers (ie, digitalis compounds), calcium channel blockers, and beta-adrenergic blockers. This article reviews the various electrocardiographic abnormalities associated with these 5 classes of agents, ranging from morphological abnormalities and conduction blocks to brady- and tachyarrhythmias.
authors.affiliation: Department of Emergency Medicine, University of Virginia, Charlottesville, VA 22911, USA. ch2xf@virginia.edu
authors.forename: Christopher
authors.initials: C
authors.lastname: Delk
authors.forename: Christopher P
authors.initials: CP
authors.lastname: Holstege
authors.forename: William J
authors.initials: WJ
authors.lastname: Brady
mesh_terms: D000319:Adrenergic beta-Antagonists / Q000494:pharmacology / Q000506:poisoning; D000328:Adult; D000368:Aged; D001145:Arrhythmias, Cardiac / Q000139:chemically induced* / Q000175:diagnosis; D002121:Calcium Channel Blockers / Q000494:pharmacology / Q000506:poisoning; D004071:Digitalis Glycosides / Q000494:pharmacology / Q000506:poisoning; D004562:Electrocardiography / Q000187:drug effects*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011041:Poisoning / Q000503:physiopathology*; D026902:Potassium Channel Blockers / Q000494:pharmacology / Q000506:poisoning; D026941:Sodium Channel Blockers / Q000494:pharmacology / Q000506:poisoning
chemical_list: D000319:Adrenergic beta-Antagonists; D002121:Calcium Channel Blockers; D004071:Digitalis Glycosides; D026902:Potassium Channel Blockers; D026941:Sodium Channel Blockers