Considerations on intervention goal and efficacy evaluation of traditional Chinese medicine in the treatment of neurological diseases.
In the last several years, traditional Chinese medicine (TCM) has made much progress in the treatment of neurological diseases. The living space of TCM in neurological diseases lies in refractory diseases, aging and chronic diseases caused by multiple factors as well as sub-health state and chronic fatigue state. The effect model of TCM mainly consists of whole effect, self-organization, self-stable model, holographic effect and butterfly effect. The effective point of TCM in neurological diseases lies mainly in end-points and health-related events. Moreover, TCM has advantages in the evaluation of symptoms, syndrome and quality of life (QOL). Some key indexes should be included when evaluating the efficacy of TCM in neurological diseases. Meanwhile, the advantages of TCM such as end-points, health-related events and QOL should be highlighted. Multi-subject researching methods could be adopted to make a comprehensive evaluation of subjective and objective indexes. The clinical evidence on the TCM efficacy evaluation may come from RCTs, and other types of designs can also be considered.
Xie
Ren-ming
RM
Neurological Researching Centre, Guangdong Province Hospital, Guangzhou, 510120, China. xrm77@hotmail.com
Du
Bao-xin
BX
Huang
Yan
Y
Zhou
Dao-you
DY
Wang
Yong-yan
YY
Huang
Pei-xin
PX
D000375:Aging; D006801:Humans; D008516:Medicine, Chinese Traditional; D009422:Nervous System Diseases / Q000188:drug therapy* / Q000523:psychology; D011788:Quality of Life