title: [Bullae and blisters--differential diagnosis].
abstract: Circumscribed collections of fluid in the skin are termed blisters or blebs (roughly up to 1 cm) or bullae (roughly upwards of 1 cm). They may be subcorneal (e.g. impetigo contagiosa, pemphigus foliaceus), intra-epidermal (e.g. pemphigus vulgaris, epidermolysis bullosa simplex), junctional (e.g. bullous pemphigoid) or subepidermal (epidermolysis bullosa dystrophica). Puss-filled vesicles are termed pustules. Impetigo contagiosa is by far the most common vesicle-forming disease seen in children. As a rule,the diagnosis and treatment are unproblematic. At the latest when suitable therapy fails to elicit a response and/or in the absence of pyogens, the less common differential diagnoses must be considered.
authors.affiliation: Klinik und Poliklinik für Dermatologie am Biederstein TU München. nina.schnopp@lrz.tu-muenchen.de
authors.forename: C
authors.initials: C
authors.lastname: Schnopp
mesh_terms: D002648:Child; D002675:Child, Preschool; D003937:Diagnosis, Differential; D004820:Epidermolysis Bullosa / Q000175:diagnosis / Q000628:therapy; D005194:Family Practice; D006801:Humans; D007169:Impetigo / Q000175:diagnosis / Q000628:therapy; D007223:Infant; D008415:Mastocytosis / Q000175:diagnosis; D012872:Skin Diseases, Vesiculobullous / Q000175:diagnosis* / Q000209:etiology / Q000628:therapy