In vitro hypoglycemic activity of methanolic extract of some indigenous plants.
Pakistan is rich in medicinally important plants and has ancient herbal treatment methods. Present work is based on the study of six indigenous plants Eugenia jambolana, Lawsonia inermis, Momordica charantia, Morus alba, Nigella sativa and Trigonella foenum graecum which show the inhibitory effect of glucose utilization, and are in use as hypoglycemic agents of varying degree in traditional system of medicine. The glucose uptake activity of (methanolic extracts) of these plants was tested in vitro and glucose was estimated by glucose oxidase method. The results in three different media revealed that, hypoglycemic activity is more prominent in neutral and basic media as compared to acidic medium.
Arayne
M Saeed
MS
Department of Chemistry, University of Karachi, Karachi-75270, Pakistan. msarayne@gmail.com
Sultana
Najma
N
Mirza
Agha Zeeshan
AZ
Zuberi
M Hashim
MH
Siddiqui
Farhan Ahmed
FA
D005947:Glucose / Q000737:chemistry; D006863:Hydrogen-Ion Concentration; D007004:Hypoglycemic Agents / Q000737:chemistry / Q000302:isolation & purification*; D031564:Lawsonia Plant / Q000737:chemistry; D000432:Methanol; D029777:Momordica charantia / Q000737:chemistry; D031625:Morus / Q000737:chemistry; D031881:Nigella sativa / Q000737:chemistry; D010936:Plant Extracts / Q000737:chemistry / Q000302:isolation & purification*; D010946:Plants, Medicinal / Q000737:chemistry*; D027842:Syzygium / Q000737:chemistry; D029910:Trigonella / Q000737:chemistry
D007004:Hypoglycemic Agents; D010936:Plant Extracts; D005947:Glucose; D000432:Methanol