title: [A case of aortitis syndrome diagnosed with 18F-fluorodeoxyglucose-positron tomography (18F-FDG-PET) in the early pre-pulseless phase].
abstract: A 14-year-old girl with aortitis syndrome in the early pre-pulseless phase was admitted to our hospital because of slight fever, neck bruit, asymmetrical blood pressure, stenosis or dilatation of the main branch arteries in aorta on chest computed tomography. Laboratory examination revealed a high level of C-reactive protein and an elevated erythrocyte sedimentation rate, as well as hypergammaglobulinemia, and 18F-FDG-PET revealed an accumulation of 18 fluorodeoxyglucose in the great vessels. She was first given pulse therapy with a combination of methylprednisolone and intravenous cyclophosphamide, and then maintenance therapy with oral prednisolone and azathioprine. All the abnormal laboratory parameters improved to normal levels within a month. We suggest that early diagnosis of aortitis syndrome may permit early treatment in the early pre-pulseless phase and could possibly prevent progression to the occlusive phase.
authors.affiliation: Department of Pediatrics, Yokohama City University.
authors.forename: Jumpei
authors.initials: J
authors.lastname: Kinoshita
authors.forename: Yasuo
authors.initials: Y
authors.lastname: Nakagishi
authors.forename: Remi
authors.initials: R
authors.lastname: Ozawa
authors.forename: Rumiko
authors.initials: R
authors.lastname: Kurosawa
authors.forename: Tomoyuki
authors.initials: T
authors.lastname: Imagawa
authors.forename: Masaaki
authors.initials: M
authors.lastname: Mori
authors.forename: Toshihiro
authors.initials: T
authors.lastname: Mitsuda
authors.forename: Yuko
authors.initials: Y
authors.lastname: Aihara
authors.forename: Kunio
authors.initials: K
authors.lastname: Hashimoto
authors.forename: Noriko
authors.initials: N
authors.lastname: Mukoyama
authors.forename: Shumpei
authors.initials: S
authors.lastname: Yokota
mesh_terms: D000293:Adolescent; D001015:Aortic Arch Syndromes / Q000000981:diagnostic imaging*; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D049268:Positron-Emission Tomography
chemical_list: D019788:Fluorodeoxyglucose F18