title: Frequent hemodialysis in children.
abstract: Frequent hemodialysis is currently conducted in a limited number of pediatric dialysis centers. However, the preliminary experience with children who have undergone procedures such as "daily" intensive hemodiafiltration and nocturnal hemodialysis has been positive, with the allowance for unrestricted diets and fluid intake, the lack of need for phosphate binders, excellent metabolic and blood pressure control, and, in the case of hemodiafiltration, excellent growth. The provision of frequent daily hemodialysis with the NxStage System has also recently been introduced to pediatrics. An overview about what is currently understood regarding the technical and clinical application of these approaches to therapy for children with end-stage renal disease form the basis for this article and highlight the impact of the procedures to date and the need for additional experience and collaborative data collection.
authors.affiliation: The Children's Mercy Hospital, Kansas City, MO 64108, USA. bwarady@cmh.edu
authors.forename: Bradley A
authors.initials: BA
authors.lastname: Warady
authors.forename: Michel
authors.initials: M
authors.lastname: Fischbach
authors.forename: Denis
authors.initials: D
authors.lastname: Geary
authors.forename: Stuart L
authors.initials: SL
authors.lastname: Goldstein
mesh_terms: D000367:Age Factors; D002648:Child; D002675:Child, Preschool; D005260:Female; D017583:Hemodiafiltration / Q000009:adverse effects / Q000379:methods / Q000706:statistics & numerical data; D015312:Hemodialysis Solutions / Q000493:pharmacokinetics* / Q000627:therapeutic use; D006801:Humans; D015994:Incidence; D007676:Kidney Failure, Chronic / Q000175:diagnosis / Q000401:mortality / Q000628:therapy*; D008297:Male; D009551:Night Care / Q000379:methods; D011379:Prognosis; D006435:Renal Dialysis / Q000009:adverse effects / Q000379:methods* / Q000706:statistics & numerical data*; D018570:Risk Assessment; D016896:Treatment Outcome
chemical_list: D015312:Hemodialysis Solutions