title: Primary ventriculitis caused by Streptococcus intermedius.
abstract: Streptococcus intermedius is increasingly being recognised as an aetiological agent in central nervous system infections. Primary ventriculitis caused by this organism has not been reported so far. We present a case of primary ventriculitis, which resulted in adhesions and multiloculated hydrocephalus, necessitating numerous surgical procedures to control it. No predisposing factor(s) could be identified. Although the organism could not be cultured from CSF, as he was already on antibiotic treatment, it could, however, be identified by 16S rDNA polymerase chain reaction on the CSF sample. It appears important to recognise this condition and to treat it aggressively to prevent complications such as adhesions and multiloculated hydrocephalus.
authors.affiliation: Department of Neurosurgery, Southampton General Hospital, Southampton, UK.
authors.forename: G V
authors.initials: GV
authors.lastname: Vajramani
authors.forename: H
authors.initials: H
authors.lastname: Akrawi
authors.forename: G
authors.initials: G
authors.lastname: Jones
authors.forename: O C E
authors.initials: OC
authors.lastname: Sparrow
mesh_terms: D000890:Anti-Infective Agents / Q000627:therapeutic use*; D002439:Cefotaxime / Q000627:therapeutic use; D002552:Cerebral Ventricles / Q000601:surgery; D004660:Encephalitis / Q000150:complications / Q000382:microbiology* / Q000628:therapy; D004724:Endoscopy; D015600:Glasgow Coma Scale; D006801:Humans; D006849:Hydrocephalus / Q000209:etiology* / Q000628:therapy; D008297:Male; D008795:Metronidazole / Q000627:therapeutic use; D008875:Middle Aged; D012293:Rifampin / Q000627:therapeutic use; D013290:Streptococcal Infections / Q000175:diagnosis / Q000188:drug therapy; D034367:Streptococcus intermedius / Q000302:isolation & purification; D014057:Tomography, X-Ray Computed
chemical_list: D000890:Anti-Infective Agents; D008795:Metronidazole; D002439:Cefotaxime; D012293:Rifampin