title: High-performance liquid chromatography with atmospheric pressure chemical ionization and electrospray ionization mass spectrometry for analysis of Angelica sinensis.
abstract: An HPLC-PAD-API/MS method for analysing the chemical constituents of Angelica sinensis (A. sinensis) has been developed. ESI and APCI spectra, in both positive ion (PI) and negative ion (NI) modes, provided very useful information concerning the molecular weights of detected compounds. By comparing the retention times, UV spectra, mass spectra and molecular weights of detected compounds with those published in literature, 15 constituents of A. sinensis could be tentatively identified. This technique involving combined MS information may provide an objective, reliable and rapid analytical method for the quality control and database research of traditional Chinese medicines.
authors.affiliation: Research Center of Modernization of Chinese Herbal Medicines, Central South University, Changsha 410083, People's Republic of China.
authors.forename: Ya-Li
authors.initials: YL
authors.lastname: Wang
authors.forename: Yi-Zeng
authors.initials: YZ
authors.lastname: Liang
authors.forename: Ben-Mei
authors.initials: BM
authors.lastname: Chen
mesh_terms: D029971:Angelica sinensis / Q000737:chemistry*; D001274:Atmospheric Pressure; D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D015394:Molecular Structure; D008970:Molecular Weight; D021241:Spectrometry, Mass, Electrospray Ionization / Q000379:methods*