title: Biomimetically synthesized polymer-hydroxyapatite sheet like nano-composite.
abstract: Biomimetic internal architecture is proving valuable for multi-tissue and structural tissue interface engineering. A biomimetic method developed for the in situ synthesis of hydroxyapatite in poly (vinyl) alcohol, produces nanocomposites in the form of fabric-like sheets, when subjected to lyophilisation. The surface reactive hydroxyl groups of poly (vinyl) alcohol encourage site-specific coupling of hydroxyapatite. This results in improved mechanical properties, which may be better for biomedical applications when compared to a mere blend of the above two.
authors.affiliation: Materials Science and Technology Division, National Metallurgical Laboratory, Burmamines, Jamshedpur 831007 Jharkhand, India. nayar@nmlindia.org
authors.forename: Suprabha
authors.initials: S
authors.lastname: Nayar
authors.forename: Ashit Kumar
authors.initials: AK
authors.lastname: Pramanick
authors.forename: Binay K
authors.initials: BK
authors.lastname: Sharma
authors.forename: Gautam
authors.initials: G
authors.lastname: Das
authors.forename: B
authors.initials: B
authors.lastname: Ravi Kumar
authors.forename: Arvind
authors.initials: A
authors.lastname: Sinha
mesh_terms: D001672:Biocompatible Materials / Q000737:chemistry; D001698:Biomedical Engineering / Q000379:methods; D032701:Biomimetics; D017886:Durapatite / Q000737:chemistry*; D005612:Freeze Drying; D008422:Materials Testing; D018625:Microscopy, Atomic Force; D008855:Microscopy, Electron, Scanning; D046529:Microscopy, Electron, Transmission; D053761:Nanocomposites / Q000737:chemistry*; D011108:Polymers / Q000737:chemistry*; D011142:Polyvinyl Alcohol / Q000737:chemistry; D017550:Spectroscopy, Fourier Transform Infrared; D013499:Surface Properties; D023822:Tissue Engineering / Q000379:methods
chemical_list: D001672:Biocompatible Materials; D011108:Polymers; D011142:Polyvinyl Alcohol; D017886:Durapatite