The relationship between antioxidant nutrient intake and cataracts in older people.
This study investigated the relationship between the intake of antioxidant nutrients and the suffering of cataracts in 177 institutionalized elderly people (61 men and 116 women) aged > or = 65 years. Dietary intake was monitored for 7 consecutive days using a "precise individual weighing" method. Subjects, who during their earlier years were exposed by their work to sunlight, had a greater risk of suffering cataracts (OR = 3.2; CI: 1.1-9.3, P < 0.05) than those who worked indoors. A relationship was found between increased vitamin C intake and a reduced prevalence of cataracts (i.e., when comparing those above P95 for vitamin C intake with those below P5; (OR = 0.08; CI: 0.01-0.75, P 0.05). Among subjects with cataracts, 12.1% had vitamin C intakes of < 61 mg/day (P10) and only 2.2% had intakes of > 183 mg/day (P95) (p < 0.01). Subjects who consumed > 3290 microg/day (P95) of lutein were less likely to have cataracts (OR = 0.086; CI: 0.007-1.084; p < 0.05) than those whose consumption was < 256 microg/day (P5). In men, high intakes of zeaxanthin seemed to provide a protective effect against the problem (OR = 0.96; CI: 0.91-0.99; p < 0.05). The results suggest an association exists between exposure to sunlight and the development of cataracts, and that vitamin C, lutein, and zeaxanthin offer some protection against this disorder.
Rodríguez-Rodríguez
Elena
E
Departamento de Nutrición, Facultad de Farmacia, Universidad Complutense, 28040-Madrid, Spain.
Ortega
Rosa M
RM
López-Sobaler
Ana M
AM
Aparicio
Aranzazu
A
Bermejo
L M
LM
Marín-Arias
Lilliam I
LI
D000368:Aged; D000369:Aged, 80 and over; D000375:Aging; D000975:Antioxidants / Q000008:administration & dosage*; D001205:Ascorbic Acid / Q000008:administration & dosage; D002386:Cataract / Q000453:epidemiology*; D004032:Diet / Q000706:statistics & numerical data*; D004034:Diet Surveys; D005260:Female; D015577:Geriatric Assessment / Q000379:methods; D006801:Humans; D014975:Lutein / Q000008:administration & dosage; D008297:Male; D016017:Odds Ratio; D017678:Sex Distribution; D013030:Spain / Q000453:epidemiology; D013472:Sunlight / Q000009:adverse effects; D024341:Xanthophylls / Q000008:administration & dosage; D065146:Zeaxanthins
D000975:Antioxidants; D024341:Xanthophylls; D065146:Zeaxanthins; D001205:Ascorbic Acid; D014975:Lutein