title: Measurement of visco-elastic properties of breast-tissue mimicking materials using diffusing wave spectroscopy.
abstract: Diffusing wave spectroscopy (DWS), without the use of tracer particles, has been used to study the internal dynamics of polyvinyl alcohol (PVA) phantoms, which mimic the properties of normal and malignant breast tissues. From the measured intensity autocorrelations, the mean square displacement (MSD) of phantom meshing is estimated, leading to the storage and loss moduli of the medium covering frequencies up to 10 KHz. These are verified with independent measurements from a dynamic mechanical analyzer (DMA) at low frequencies. We thus prove the usefulness of DWS to extract visco-elastic properties of the phantom and its possible application in detecting malignancy in soft tissues.
authors.affiliation: Indian Institute of Science, Department of Instrumentation, Bangalore 560 012, India.
authors.forename: C Usha
authors.initials: CU
authors.lastname: Devi
authors.forename: R Sreekumari
authors.initials: RS
authors.lastname: Bharat Chandran
authors.forename: R Mohan
authors.initials: RM
authors.lastname: Vasu
authors.forename: Ajay K
authors.initials: AK
authors.lastname: Sood
mesh_terms: D000465:Algorithms; D001940:Breast / Q000473:pathology / Q000503:physiopathology*; D001943:Breast Neoplasms / Q000175:diagnosis* / Q000503:physiopathology*; D003936:Diagnosis, Computer-Assisted / Q000379:methods*; D004548:Elasticity; D006801:Humans; D019047:Phantoms, Imaging; D013057:Spectrum Analysis / Q000295:instrumentation / Q000379:methods*; D014783:Viscosity