Crimean-Congo hemorrhagic fever: five patients with hemophagocytic syndrome.
Three pediatric and two adult Turkish patients with Crimean Congo Hemorrhagic Fever (CCHF) induced hemophagocytic syndrome (HPS) were admitted to Ondokuz Mayis University Hospital, which is in the Middle Black Sea Region of Turkey. All of them had remarkable hemophagocytosis in the bone marrow with severe bleeding symptoms along with the other known clinical and laboratory findings of CCHF. We would like to present these patients and to discuss the pathophysiology and the effect of acquired HPS on the severity of the disease.
Tasdelen Fisgin
Nuriye
N
Department of Clinical Microbiology and Infectious Disease, Ondokuz Mayis University, Medical School, Samsun, Turkey. nuriyetf@omu.edu.tr
Fisgin
Tunc
T
Tanyel
Esra
E
Doganci
Levent
L
Tulek
Necla
N
Guler
Nil
N
Duru
Feride
F
D000293:Adolescent; D000368:Aged; D001853:Bone Marrow / Q000473:pathology; D002675:Child, Preschool; D005260:Female; D006479:Hemorrhagic Fever, Crimean / Q000473:pathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010586:Phagocytes / Q000473:pathology*; D013577:Syndrome