title: [Effect of tobacco consumption on the spermatogenesis in males with idiopathic infertility].
abstract: OBJECTIVE
  Our objective was to relate the tobacco with seminal spermatogenic parameters such as sperm morphology, concentration of spermatozoids and germinal cells in samples of semen from men with idiopatic infertility.
  
  
  METHODS
  A prospective study was carried out on a population of 131 men with idiopatic infertility that attended the Reproduction Service of Centenario Hospital in Rosario from may 2004 to june 2006. Sperm study according to WHO was carried out evaluating germinal cells and sperm morphology with Papannicolaou. The concentration of spermatozoids was determined by means of a subjective method with Neubauer camera. The studied population was divided in the three groups: G1: smokers more of 20 cigarettes/day, G2: smokers under 20 cigarettes/day, G3 non smokers. The smokers had had the habit for over a year.
  
  
  RESULTS
  Results were analyzed with the student's t-test. Statistically significant differences between G1 vs G3 (p<0.001) and G2 vs G3 (p<0.005) were found for the three variables. No significant difference was found between the groups of smokers G1 vs G2 (p>0.1).
  
  
  CONCLUSIONS
  The results show that tobacco alters sperm concentration and morphology with an increase of immature forms, demonstrating an altered spermatogenesis process. The consumption of tobacco should be evaluated to carry out the integral study of infertile man.
authors.affiliation: Departamento de Bioquímica Clínica, Facultad de Ciencias Bioquímicas y Farmacéuticas, Facultad de Ciencias Médicas, Universidad Nacional Rosario, Rosario, Argentina. beatrizbouvet@infovia.com.ar
authors.forename: Beatriz
authors.initials: B
authors.lastname: Reina Bouvet
authors.forename: Cecilia
authors.initials: C
authors.lastname: Vicenta Paparella
authors.forename: Rodolfo
authors.initials: R
authors.lastname: Nestor Feldman
mesh_terms: D002452:Cell Count; D005854:Germ Cells; D006801:Humans; D007248:Infertility, Male / Q000209:etiology* / Q000473:pathology; D008297:Male; D011446:Prospective Studies; D012907:Smoking / Q000009:adverse effects*; D013076:Sperm Count; D013091:Spermatogenesis; D013094:Spermatozoa / Q000166:cytology