title: Generalized alternating stimulation: a novel method to reduce stimulus artifact in electrically evoked compound action potentials.
abstract: Stimulus artifact is one of the main limitations when considering electrically evoked compound action potential for clinical applications. Alternating stimulation (average of recordings obtained with anodic-cathodic and cathodic-anodic bipolar stimulation pulses) is an effective method to reduce stimulus artifact when evoked potentials are recorded. In this paper we extend the concept of alternating stimulation by combining anodic-cathodic and cathodic-anodic recordings with a weight in general different to 0.5. We also provide an automatic method to obtain an estimation of the optimal weights. Comparison with conventional alternating, triphasic stimulation and masker-probe paradigm shows that the generalized alternating method improves the quality of electrically evoked compound action potential responses.
authors.affiliation: Department of Signal Theory, Telematics and Communications, University of Granada, Spain. atv@ugr.es
authors.forename: Isaac
authors.initials: I
authors.lastname: Alvarez
authors.forename: Angel
authors.initials: A
authors.lastname: de la Torre
authors.forename: Manuel
authors.initials: M
authors.lastname: Sainz
authors.forename: Cristina
authors.initials: C
authors.lastname: Roldan
authors.forename: Hansjoerg
authors.initials: H
authors.lastname: Schoesser
authors.forename: Philipp
authors.initials: P
authors.lastname: Spitzer
mesh_terms: D000200:Action Potentials / Q000502:physiology*; D016477:Artifacts; D003054:Cochlear Implants; D003055:Cochlear Microphonic Potentials / Q000502:physiology*; D004558:Electric Stimulation; D004594:Electrophysiology / Q000379:methods*; D008962:Models, Theoretical