An isolated pituitary metastasis as presentation of a differentiated hepatocellular carcinoma mimicking a nonfunctioning macroadenoma.
The differential diagnosis of sellar masses may be complex. Metastatic disease constitutes 1% of all pituitary lesions and sometimes mimics the clinical-radiological presentation of pituitary adenoma. The definitive diagnosis usually relies on histology, but occasionally even histological features of pituitary metastasis may resemble those of adenomas. We present a patient initially diagnosed with pituitary adenoma, but whose clinical course finally revealed pituitary metastasis of a hepatocellular carcinoma. The existing literature on this topic is reviewed.
Moreno-Perez
O
O
Department of Endocrinology and Nutrition, Alicante University General Hospital, Alicante, Spain. oscarmorenop76@hotmail.com
Peiró
F M
FM
López
P
P
Boix
E
E
Meoro
A
A
Serna-Candel
C
C
Aranda
F I
FI
Picó
A M
AM
D000236:Adenoma / Q000473:pathology*; D000368:Aged; D006528:Carcinoma, Hepatocellular / Q000556:secondary*; D003937:Diagnosis, Differential; D006801:Humans; D008113:Liver Neoplasms / Q000473:pathology*; D008279:Magnetic Resonance Imaging; D008297:Male; D010911:Pituitary Neoplasms / Q000556:secondary*