Differences in lectin-binding properties between the common mucosal epithelium and follicle-associated epithelium in the rabbit small intestine.
Differences in sugar distribution between the villous epithelium and follicle-associated epithelium (FAE) were compared using lectins in the rabbit small intestine. In every portion, villous columnar epithelial cells primarily exhibited a positive reaction to the GalNAc, GlcNAc, galactose, and oligosaccharide. In the ileal Peyer's patch (PP), whereas microvillous epithelial cells exhibited positive reactions, M cells tended to be negative. The villous epithelial reaction to the fucose group was negative, but M cells and microvillous epithelial cells showed a positive to the fucose. No epithelium had a positive reaction to the mannose and glucose. The variety of lectin-binding properties of villous epithelial cells and M cells may reflect specificity for the recognizing luminal substances such as antigenic molecules and bacterial elements.
Takeuchi
Takashi
T
Department of Molecular Pathology, Ehime University School of Medicine, Toh-on, Ehime, Japan.
Fujibuchi
Taketsugu
T
Imai
Yoshinori
Y
Kamei
Yoshiaki
Y
Murase
Ryuichi
R
Kito
Katsumi
K
Abe
Yasuhito
Y
Ueda
Norifumi
N
D000818:Animals; D015415:Biomarkers; D002241:Carbohydrates; D007413:Intestinal Mucosa / Q000166:cytology / Q000378:metabolism*; D007421:Intestine, Small / Q000033:anatomy & histology / Q000378:metabolism*; D037102:Lectins / Q000378:metabolism*; D008297:Male; D011485:Protein Binding; D011817:Rabbits
D015415:Biomarkers; D002241:Carbohydrates; D037102:Lectins