title: Rare C-6 vertebral involvement in a child with histiocytosis X: case report.
abstract: The authors present a rare case of C-6 vertebral involvement in a 12-year-old boy with histiocytosis X. The patient presented with limitation in movements of neck and upper extremities. Computed tomography (CT) and magnetic resonance (MRI) imaging were used in the preoperative workup. Surgery was performed via an anterior cervical approach along with stabilization using a fibula strut graft and plate fixation. Pathological assessment showed infiltration of Langerhans cells accompanied by a mixture of many eosinophils, giant cells, neutrophils and foamy cells. The patient went on to make a full recovery with complete resolution of his motor weakness. In an extensive review of the literature there are very few cases of cervical histiocytosis X reported. In addition, surgical management of this type of lesion has rarely been discussed.
authors.affiliation: Pediatric Neurosurgery, Children's Hospital, 1600 7th Avenue South ACC 400, Birmingham, AL 35233, USA.
authors.forename: Firouz
authors.initials: F
authors.lastname: Salehpour
authors.forename: R Shane
authors.initials: RS
authors.lastname: Tubbs
authors.forename: Sina
authors.initials: S
authors.lastname: Zarrintan
authors.forename: Ali
authors.initials: A
authors.lastname: Meshkini
authors.forename: Shahram
authors.initials: S
authors.lastname: Hadidchi
authors.forename: Hojjat
authors.initials: H
authors.lastname: Pourfathi
authors.forename: Ramin
authors.initials: R
authors.lastname: Azhough
authors.forename: Asharf
authors.initials: A
authors.lastname: Fakhrjou
authors.forename: James T
authors.initials: JT
authors.lastname: Goodrich
authors.forename: Amir Afshin
authors.initials: AA
authors.lastname: Khaki
mesh_terms: D002574:Cervical Vertebrae / Q000473:pathology* / Q000601:surgery; D002648:Child; D006646:Histiocytosis, Langerhans-Cell / Q000473:pathology* / Q000503:physiopathology* / Q000601:surgery; D006801:Humans; D008297:Male; D018908:Muscle Weakness / Q000209:etiology; D019635:Neurosurgical Procedures; D013117:Spinal Cord Compression / Q000209:etiology / Q000601:surgery; D013122:Spinal Diseases / Q000473:pathology* / Q000601:surgery