title: Neurodevelopment in very low birth weight premature infants with postnatal subependymal cysts.
abstract: The aim of this study was to investigate the neurodevelopmental outcome in very low birth weight infants with postnatal subependymal cysts. During a 3-year period, postnatal subependymal cysts were diagnosed by serial cranial ultrasound in 21 very low birth weight infants born prior to 33 weeks' gestation. These infants and 116 healthy very low birth weight controls were evaluated with the Bayley Scales of Infant Development at 2 years of age. Preterm infants with postnatal subependymal cysts had a significantly lower Psychomotor Development Index (P = .034) and were more likely than the normal group to have motor developmental delay (Psychomotor Development Index <70) (P = .013). The findings indicate that postnatal subependymal cyst is a significant risk factor for impaired motor development in very low birth weight infants (odds ratio 5.73, 95% confidence interval 1.57-20.97).
authors.affiliation: Department of Physical Medicine and Rehabilitation, Mackay Memorial Hospital, Taipei, Taiwan. pmrchia@yahoo.com
authors.forename: Yao-Chia
authors.initials: YC
authors.lastname: Chuang
authors.forename: Chia
authors.initials: C
authors.lastname: Lee
authors.forename: Nan-Chang
authors.initials: NC
authors.lastname: Chiu
authors.forename: Chyong-Hsin
authors.initials: CH
authors.lastname: Shu
authors.forename: Han-Yang
authors.initials: HY
authors.lastname: Hung
authors.forename: Hsin-An
authors.initials: HA
authors.lastname: Kao
authors.forename: Jui-Hsing
authors.initials: JH
authors.lastname: Chang
mesh_terms: D001927:Brain Diseases / Q000000981:diagnostic imaging / Q000503:physiopathology*; D016001:Confidence Intervals; D003560:Cysts / Q000000981:diagnostic imaging / Q000473:pathology / Q000503:physiopathology*; D002658:Developmental Disabilities / Q000000981:diagnostic imaging / Q000503:physiopathology*; D004805:Ependyma / Q000000981:diagnostic imaging / Q000473:pathology*; D005260:Female; D005865:Gestational Age; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007234:Infant, Premature; D007235:Infant, Premature, Diseases; D019102:Infant, Very Low Birth Weight; D008137:Longitudinal Studies; D008297:Male; D016017:Odds Ratio; D012307:Risk Factors; D012720:Severity of Illness Index; D014463:Ultrasonography