title: Alternative surgical treatment for giant-cell reparative granuloma in the metacarpal, using phenol and ethanol adjuvant therapy.
abstract: Giant-cell reparative granuloma (GCRG) or a solid variant of an aneurysmal bone cyst (ABC) is an uncommon benign reactive lesion with a predilection for the small tubular bones of the hands and feet. Treatment usually involves wide resection or amputation because of unacceptable high recurrence rates after curettage. Adjuvant therapy usually is applied to reduce the recurrence of locally aggressive bone tumors. We report 2 cases of GCRG that were treated successfully with curettage, adjuvant phenol and ethanol, and autogenous bone grafting.
authors.affiliation: Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
authors.forename: Tatsuya
authors.initials: T
authors.lastname: Yoshida
authors.forename: Akio
authors.initials: A
authors.lastname: Sakamoto
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Tanaka
authors.forename: Shuichi
authors.initials: S
authors.lastname: Matsuda
authors.forename: Yoshinao
authors.initials: Y
authors.lastname: Oda
authors.forename: Yukihide
authors.initials: Y
authors.lastname: Iwamoto
mesh_terms: D000328:Adult; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D001847:Bone Diseases / Q000473:pathology / Q000628:therapy*; D017024:Chemotherapy, Adjuvant; D002648:Child; D003475:Curettage; D000431:Ethanol / Q000627:therapeutic use*; D005260:Female; D006101:Granuloma, Giant Cell / Q000473:pathology / Q000628:therapy*; D006801:Humans; D007085:Ilium / Q000637:transplantation; D008297:Male; D050279:Metacarpal Bones / Q000473:pathology / Q000601:surgery*; D009364:Neoplasm Recurrence, Local / Q000517:prevention & control; D019800:Phenol / Q000627:therapeutic use*
chemical_list: D000970:Antineoplastic Agents; D019800:Phenol; D000431:Ethanol