title: Effectiveness of recombinant activated factor VII (rFVII a) for controlling intractable postpartum bleeding: report of two cases and literature review.
abstract: BACKGROUND
  Recombinant activated factor VII is used for the treatment in patients with inherited or acquired hemophilia with inhibitors and congenital factor VII deficiencies.
  
  
  OBJECTIVE
  Using recombinant activated factor VII in primary postpartum hemorrhage.
  
  
  METHODS
  Two cases of women who had postpartum hemorrhage and were treated with recombinant activated factor VII after all conventional treatment failed.
  
  
  RESULTS
  The intractable hemorrhage stopped after treatment with recombinant activated factor VII CONCLUSION: The present report showed that massive postpartum hemorrhage that failed to all procedures was controlled successfully by recombinant activated factor VII.
authors.affiliation: Department of Obstetrics and Gynecology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University Rama VI Rd, Bangkok 10400, Thailand. ramjy@mahidol.ac.th
authors.forename: Mayuree
authors.initials: M
authors.lastname: Jirapinyo
authors.forename: Jittima
authors.initials: J
authors.lastname: Manonai
authors.forename: Yongyoth
authors.initials: Y
authors.lastname: Herabutya
authors.forename: Suporn
authors.initials: S
authors.lastname: Chuncharunee
mesh_terms: D000328:Adult; D015942:Factor VIIa / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D006473:Postpartum Hemorrhage / Q000188:drug therapy* / Q000517:prevention & control; D011247:Pregnancy; D011994:Recombinant Proteins / Q000627:therapeutic use*; D017211:Treatment Failure; D016896:Treatment Outcome
chemical_list: D011994:Recombinant Proteins; D015942:Factor VIIa