[Studies on chemical constituents in root of Isatis indigotica].
OBJECTIVE
To study the chemical constituents in the root of Isatis indigotica.


METHODS
The constituents root were separated through various chromatographic techniques and their structures were elucidated by means of physicochemical properties and the analysis of their spectral data.


RESULTS
Eleven compounds were isolated and identified as (+) -isolariciresinol (1), lariciresinol (2), lariciresinol-9-O-beta-D-glucopyranoside (3), lariciresinol-4'-O-beta-D-glucopyranoside (4), lariciresinol-4,4'-bis-O-beta-D-glucopyranoside (5), 3-formylindole (6), 1-methoxy-3-indolecarbaldehyde (7), 1-methoxy-3-indoleacetonitrile (8), deoxyvasicinone (9), epigoitrin (10), adenosine (11).


CONCLUSIONS
Compounds 4-8 were isolated from I. indigotica for the first time.
Zuo
Li
L
Institute of Materia Medica, CAMS & PUMC, Beijing 100050, China.
Li
Jian-bei
JB
Xu
Jing
J
Yang
Jing-zhi
JZ
Zhang
Dong-ming
DM
Tong
Yong-ling
YL
D005663:Furans / Q000032:analysis / Q000737:chemistry / Q000302:isolation & purification; D005960:Glucosides / Q000032:analysis / Q000737:chemistry / Q000302:isolation & purification; D007211:Indoles / Q000032:analysis / Q000737:chemistry / Q000302:isolation & purification; D031219:Isatis / Q000737:chemistry*; D017705:Lignans / Q000032:analysis / Q000737:chemistry / Q000302:isolation & purification; D008031:Lignin / Q000032:analysis / Q000737:chemistry / Q000302:isolation & purification; D009284:Naphthols / Q000032:analysis / Q000737:chemistry / Q000302:isolation & purification; D010936:Plant Extracts / Q000032:analysis* / Q000737:chemistry / Q000302:isolation & purification; D018517:Plant Roots / Q000737:chemistry*; D010946:Plants, Medicinal / Q000737:chemistry; D021241:Spectrometry, Mass, Electrospray Ionization
C528934:3-formylindole; D005663:Furans; D005960:Glucosides; D007211:Indoles; D017705:Lignans; D009284:Naphthols; D010936:Plant Extracts; C528933:lariciresinol-4'-O-glucopyranoside; C060284:isolariciresinol; C060282:lariciresinol; D008031:Lignin