Androgenic juvenile granulosa cell tumor of the ovary with cystic presentation: a case report.
Granulosa cell tumors account for approximately 1-2% of all ovarian tumors. There are two types: adult granulosa cell tumor and juvenile granulosa cell tumor. Juvenile granulosa cell tumors constitute 5% of this histological subtype, and the prognosis is good because the majority present as Stage I tumors. The treatment can consist of conservative surgery. Androgen production is rare and produces virilization in women. These tumors are usually solid or predominantly solid. We describe the case of a 13-year-old girl with androgenic manifestations and increased abdominal size. Her plasma testosterone level was elevated. A left adnexal cyst (14.4 x 9.1 x 9.7 cm) was revealed at pelvic ultrasonography. The patient underwent an exploratory laparotomy, revealing a left ovarian cystic tumor. Diagnosis was juvenile granulosa cell tumor.
Nomelini
R S
RS
Research Institute of Oncology (IPON)/Discipline of Gynecology and Obstetrics, Federal University of Triângulo Mineiro (UFTM), Uberaba-MG, Brazil.
Micheletti
A M R
AM
Adad
S J
SJ
Murta
E F C
EF
D019326:17-alpha-Hydroxyprogesterone / Q000097:blood; D000293:Adolescent; D005260:Female; D006106:Granulosa Cell Tumor / Q000097:blood / Q000473:pathology* / Q000601:surgery*; D006801:Humans; D010051:Ovarian Neoplasms / Q000097:blood / Q000473:pathology* / Q000601:surgery*; D013739:Testosterone / Q000097:blood
D013739:Testosterone; D019326:17-alpha-Hydroxyprogesterone