Triterpenoid prosapogenols and prosapogenins from the husks of Xanthoceras sorbifolia.
Two new prosapogenins, 16-O-acetyl-21-O-(4-angeloyl)-alpha-l-rhamnopyranosyl barringtogenol C (1), 28-O-beta-d-glucopyranosyl 16-deoxybarringtogenol C (2), were isolated from the acid hydrolyzate of the crude saponin obtained from the husks of Xanthoceras sorbifolia Bunge, along with six known triterpenoids. These structures were established on the basis of chemical and detailed spectral evidences. Compounds 1 and 2 showed cytotoxic activity against human cell lines (A375-S2, HeLa).
Li
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ZL
Research Department of Natural Medicines, Shenyang Pharmaceutical University, Shenyang 110016, China.
Li
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Meng
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Sha
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D000972:Antineoplastic Agents, Phytogenic / Q000302:isolation & purification*; D045744:Cell Line, Tumor; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D029631:Sapindaceae / Q000737:chemistry*; D012503:Saponins / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
C525314:16-O-acetyl-21-O-(4-O-angeloyl)rhamnopyranosyl barringtogenol C; C525315:28-O-glucopyranosyl 16-deoxybarringtogenol C; D000972:Antineoplastic Agents, Phytogenic; D012503:Saponins; D014315:Triterpenes; C026473:prosapogenin