The synaptic Wnt signaling hypothesis.
The role of Wnt signaling in the formation of neural circuits has been well established. Here, I wish to propose a Wnt signaling cascade at the mature central synapse. The synaptic Wnt signaling may have important implications in regulation of brain functions.
Tang
Shao-Jun
SJ
Department of Neurobiology and Behavior, Center for Neurobiology of Learning and Memory, University of California, Irvine, California 92697-3800, USA. stang@uci.edu
D000818:Animals; D008954:Models, Biological; D015398:Signal Transduction / Q000502:physiology*; D013569:Synapses / Q000502:physiology*; D051153:Wnt Proteins / Q000502:physiology*
D051153:Wnt Proteins