Prenatal development of the bovine oviduct.
In this study the development of the bovine Fallopian tube was investigated using light microscopic methods. Formation and differentiation of the Müllerian duct were studied in mesonephroi of 16 embryos and fetuses with a crown-rump lengths (CRL) of 0.9-8.4 cm. The funnel field, the rostral beginning of the Müllerian duct was first observed at a CRL of 0.9 cm. It appears as a thickening of the mesothelium on the craniolateral side of the mesonephros. During later development the Müllerian duct emerges by caudal outgrowth from the funnel field. Formation of a common basal lamina surrounding the caudal tips of Müllerian and Wolffian ducts could be observed at all stages up to CRL of 2.7 cm. The mesothelium and the epithelium of the Wolffian duct adjacent to the Müllerian duct showed a modification of epithelium height in all examined stages. Probably the Wolffian duct influences the growth of Müllerian duct by epithelio-mesenchymal interactions. Fetuses from a CRL of 12.0 to 94.0 cm were used for investigation of the prenatal differentiation of the oviductal mucosa. Folding of the oviductal mucosa started at a CRL of 29.0 cm and continued until birth. Individual primary, secondary and tertiary folds are formed in special proliferation zones and epithelium-folding buds. The cellular differentiation of the oviductal epithelium involves the formation of ciliated and secretory cells during different times of prenatal development. Ciliogenesis was first detected at a CRL of 33.0 cm. Active secretory cells could be observed in the oviductal epithelium from a CRL of 64.0 cm onwards.
Kenngott
R A-M
RA
Institute of Veterinary Anatomy II, University of Munich, Veterinärstrasse 13, D-80539 Munich, Germany. r.kenngott@anat.vetmed.uni-muenchen.de
Sinowatz
F
F
D000818:Animals; D002417:Cattle / Q000033:anatomy & histology* / Q000196:embryology*; D005187:Fallopian Tubes / Q000033:anatomy & histology / Q000196:embryology* / Q000502:physiology; D005260:Female; D008297:Male; D009095:Mullerian Ducts / Q000033:anatomy & histology / Q000196:embryology / Q000502:physiology; D014928:Wolffian Ducts / Q000033:anatomy & histology / Q000196:embryology / Q000502:physiology