title: Bufadienolides from Drimia macrocentra and Urginea riparia (Hyacinthaceae: Urgineoideae).
abstract: The bufadienolides, rubellin and riparianin were isolated from the bulbs of Drimia macrocentra and Urginea riparia (Hyacinthaceae) respectively. Rubellin and riparianin contain a carbohydrate moiety doubly linked to the bufadienolide aglycone at the C-2 and C-3 positions. Riparianin showed moderate activity when tested against MCF7 (breast), TK10 (renal) and UACC62 (melanoma) cell lines.
authors.affiliation: School of Chemistry, University of KwaZulu-Natal, Howard College Campus, Durban 4041, South Africa.
authors.forename: Nivan
authors.initials: N
authors.lastname: Moodley
authors.forename: Neil R
authors.initials: NR
authors.lastname: Crouch
authors.forename: Dulcie A
authors.initials: DA
authors.lastname: Mulholland
mesh_terms: D002018:Bufanolides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D045744:Cell Line, Tumor; D004354:Drug Screening Assays, Antitumor; D006801:Humans; D019668:Liliaceae / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D021241:Spectrometry, Mass, Electrospray Ionization
chemical_list: D002018:Bufanolides; C525201:riparianin; C525200:rubellin