title: Laser Doppler skin perfusion pressure in the diagnosis of limb ischemia in patients with diabetes mellitus and/or hemodialysis.
abstract: OBJECTIVE
  We investigated whether measurement of skin perfusion pressure (SPP), as measured by laser Doppler, can be used to evaluate the severity of limb ischemia in diabetes mellitus (DM) and/or hemodialysis (HD) patients.
  
  
  METHODS
  From April 2004 to March 2005, the ankle brachial pressure index (ABPI) and SPP were evaluated in 44 consecutive lower limbs with peripheral artery disease (PAD) and in 24 patients (21 males and 3 females, aged from 45 to 84 years, with a mean age of 69.3 years) with DM and/or HD. Twelve limbs were categorized as Fontaine stage II, 19 as Fontaine stage III and 24 as Fontaine stage IV.
  
  
  RESULTS
  The SPP did not differ significantly between limbs at Fontaine stage II and those at Fontaine stage III, but it was significantly lower in limbs at Fontaine stage IV than in those at Fontaine stage II or III. The ABPI did not differ significantly among limbs at Fontaine stages II, III and IV.
  
  
  CONCLUSIONS
  The SPP, as measured by the laser Doppler technique, may be used as a standard for classifying the severity of PAD in patients with DM and/or HD.
authors.affiliation: Division of Cardiovascular Surgery, Department of Surgery, Fujita Health University, Toyoake, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Kondo
authors.forename: A
authors.initials: A
authors.lastname: Muto
authors.forename: A
authors.initials: A
authors.lastname: Dardik
authors.forename: M
authors.initials: M
authors.lastname: Nishibe
authors.forename: T
authors.initials: T
authors.lastname: Nishibe
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001916:Brachial Artery / Q000000981:diagnostic imaging / Q000503:physiopathology; D003920:Diabetes Mellitus / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000628:therapy*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007511:Ischemia / Q000150:complications / Q000000981:diagnostic imaging / Q000503:physiopathology*; D017078:Laser-Doppler Flowmetry / Q000379:methods*; D007866:Leg / Q000098:blood supply*; D008297:Male; D008833:Microcirculation / Q000502:physiology*; D008875:Middle Aged; D011379:Prognosis; D006435:Renal Dialysis / Q000379:methods*; D012189:Retrospective Studies; D012720:Severity of Illness Index; D012867:Skin / Q000098:blood supply*; D016909:Tibial Arteries / Q000000981:diagnostic imaging / Q000503:physiopathology; D018616:Ultrasonography, Doppler, Duplex