Glycosylation of tocopherols by cultured cells of Eucalyptus perriniana.
Cultured suspension cells of Eucalyptus perriniana converted exogenously administered alpha-tocopherol into alpha-tocopheryl 6-O-beta-d-glucopyranoside (46mug/gfr. wt of cells) and two biotransformation products: alpha-tocopheryl 6-O-(6-O-beta-d-glucopyranosyl)-beta-d-glucopyranoside (19mug/gfr. wt of cells) and alpha-tocopheryl 6-O-(6-O-alpha-l-rhamnopyranosyl)-beta-d-glucopyranoside (6mug/gfr. wt of cells). On the other hand, two other compounds, i.e., delta-tocopheryl 6-O-(6-O-beta-d-glucopyranosyl)-beta-d-glucopyranoside (27mug/g fr. wt of cells) and delta-tocopheryl 6-O-(6-O-alpha-l-rhamnopyranosyl)-beta-d-glucopyranoside (12mug/g fr. wt of cells), together with delta-tocopheryl 6-O-beta-d-glucopyranoside (63mug/g fr. wt of cells) were isolated from suspension cells following the administration of delta-tocopherol.
Shimoda
Kei
K
Department of Pharmacology and Therapeutics, Faculty of Medicine, Oita University, 1-1 Hasama-machi, Oita 879-5593, Japan.
Kondo
Yoko
Y
Akagi
Masaaki
M
Abe
Koichi
K
Hamada
Hatsuyuki
H
Hamada
Hiroki
H
D001711:Biotransformation; D002478:Cells, Cultured; D005052:Eucalyptus / Q000166:cytology / Q000187:drug effects / Q000378:metabolism*; D005960:Glucosides / Q000096:biosynthesis / Q000737:chemistry* / Q000378:metabolism; D006031:Glycosylation; D015394:Molecular Structure; D018514:Plant Structures / Q000166:cytology; D024505:Tocopherols / Q000378:metabolism* / Q000494:pharmacology
D005960:Glucosides; D024505:Tocopherols