A novel solid phase for selective separation of flavonoid compounds.
A novel straightforward approach to selective separation for flavonoid compounds was reported. The solid phase material was prepared by copolymerization using allyl-bromide-modified chitosan as macromonomer, and ethylene glycol dimethacrylate as cross-linker. The material was evaluated by chromatographic analysis; it exhibited high selectivity separation for quercetin and its structural analogues using different mobile phases. The material could directly trap a specific class of compounds including quercetin and kaempferol from the hydrolyzate of Ginkgo biloba extract. These results demonstrated the possibility of direct extraction of certain constituents from herb using this material.
Xia
Yong-Qing
YQ
Key Laboratory of Functional Polymer Materials, Ministry of Education, Institute of Polymer Chemistry, Nankai University, Tianjin, China.
Guo
Tian-Ying
TY
Zhao
Hai-Li
HL
Song
Mou-Dao
MD
Zhang
Bang-Hua
BH
Zhang
Bao-Long
BL
D000327:Adsorption; D048271:Chitosan / Q000737:chemistry; D002851:Chromatography, High Pressure Liquid / Q000295:instrumentation; D005240:Feasibility Studies; D005419:Flavonoids / Q000737:chemistry / Q000302:isolation & purification*; D020441:Ginkgo biloba / Q000737:chemistry; D006868:Hydrolysis; D008689:Methacrylates / Q000737:chemistry; D010936:Plant Extracts / Q000032:analysis / Q000737:chemistry
D005419:Flavonoids; D008689:Methacrylates; D010936:Plant Extracts; C004919:ethylene dimethacrylate; D048271:Chitosan