title: [Clinical features of oral allergy syndrome to plant foods allergens in Kanto regions].
abstract: BACKGROUND
  Recently, it is recognized that the patients of oral allergy syndrome (OAS) to fruits are increasing. However, there are little knowledges of the background, character, and seriousness about these patients in Kanto regions.
  
  
  OBJECTIVE
  We aimed to investigate the clinical features of OAS patients to plant origin foods in Kanto regions.
  
  
  METHODS
  The patient, who visited Sagamihara National Hospital from 2000 to 2005 and developed some allergic symptoms to plant origin foods, were studied by a questionary survey.
  
  
  RESULTS
  As for the 42 subjects, average age are 36 years old, male:female=8:34, merger of other allergic disease is 35 allergic rhinitis of 42 subjects (83%), 34 of asthma (81%), 14 of atopic dermatitis (33%). The causes of OAS symptoms are 32 rose-family fruits, 34 non-rose family fruits, 14 vegetables, 11 nuts, 2 grains subjects. As for the symptom, only in the oral and pharynx symptoms are found in 12, the systemic symptoms is 29, anaphylaxis is 11 subjects. Allergic rhinitis preceded on the 90% subjects with pollinosis, very high rate. On the other hand, the 20% of all subjects have no symptoms of allergic rhinitis.
  
  
  CONCLUSIONS
  A nasal catarrh symptoms went ahead in most of the OAS subjects in Kanto regions. In addition, considering from some patients have no black alder pollinosis and/or are allergic to many non-rose-family fruits at high frequency, there might be a broad cross-reactivity between many pollens other than alder and plant origin foods.
authors.affiliation: Clinical Research Center for Allergy and Rheumatology, Sagamihara National Hospital, Japan. e-ono@sagamihara-hosp.gr.jp
authors.forename: Emiko
authors.initials: E
authors.lastname: Ono
authors.forename: Yuji
authors.initials: Y
authors.lastname: Maeda
authors.forename: Hidenori
authors.initials: H
authors.lastname: Tanimoto
authors.forename: Yuma
authors.initials: Y
authors.lastname: Fukutomi
authors.forename: Chiyako
authors.initials: C
authors.lastname: Oshikata
authors.forename: Kiyoshi
authors.initials: K
authors.lastname: Sekiya
authors.forename: Takahiro
authors.initials: T
authors.lastname: Tuburai
authors.forename: Naomi
authors.initials: N
authors.lastname: Turikisawa
authors.forename: Mamoru
authors.initials: M
authors.lastname: Otomo
authors.forename: Masami
authors.initials: M
authors.lastname: Taniguchi
authors.forename: Houta
authors.initials: H
authors.lastname: Ishii
authors.forename: Akihiko
authors.initials: A
authors.lastname: Asahina
authors.forename: Eishi
authors.initials: E
authors.lastname: Miyazaki
authors.forename: Tosihide
authors.initials: T
authors.lastname: Kumamoto
authors.forename: Kazuo
authors.initials: K
authors.lastname: Akiyama
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D005512:Food Hypersensitivity / Q000150:complications / Q000453:epidemiology*; D005638:Fruit / Q000009:adverse effects; D006801:Humans; D007564:Japan / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D006255:Rhinitis, Allergic, Seasonal / Q000150:complications / Q000453:epidemiology*; D014675:Vegetables / Q000009:adverse effects