Three new triterpenoid saponins from the rhizomes of Impatiens pritzellii var. hupehensis.
Three new triterpenoid saponins, impatiprins A-C (1-3), together with a known triterpenoid (4) and two known triterpenoid saponins (5, 6), were isolated from the rhizomes of Impatiens pritzellii Hook. f. var. hupehensis Hook. f. The structures of 1-3 were determined by 1D and 2D NMR, FAB-MS techniques and chemical methods. Compounds 1 and 2 showed weak cytotoxicities against S-180, HeLa and HepG2 cell lines.
Zhou
X-F
XF
Faculty of Pharmaceutical Sciences, Tongji Medical College of Huazhong University of Science and Technology, Wuhan 430030, China.
Zhao
X-Y
XY
Tang
L
L
Ruan
H-L
HL
Zhang
Y-H
YH
Pi
H-F
HF
Xiao
W-L
WL
Sun
H-D
HD
Wu
J-Z
JZ
D000818:Animals; D000972:Antineoplastic Agents, Phytogenic / Q000302:isolation & purification*; D006801:Humans; D029069:Impatiens / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D051379:Mice; D008807:Mice, Inbred BALB C; D027343:Rhizome / Q000737:chemistry*; D012503:Saponins / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
C525311:3-O-((6-O-ethyl)glucuronopyranosyl)echinocystic acid; C525313:3-O-((6-O-n-butyl)glucuronopyranosyl)-28-O-(xylopyranosyl-1-4-rhamnopyranosyl-1-2-xylopyranosyl)echinocystic acid; C525312:3-O-((6-O-n-butyl)glucuronopyranosyl)echinocystic acid; D000972:Antineoplastic Agents, Phytogenic; D012503:Saponins; D014315:Triterpenes