[The methods of establishing rhinogenic model of acute sinusitis in the rabbit].
OBJECTIVE
To create a rhinogenic model of acute sinusitis in the rabbits.


METHODS
Thirty-two New Zealand white rabbits were divided into four groups: A group (nasal cavity-implanted with synthetic sponge), B group (nasal cavity-implanted with synthetic sponge and bacteria inoculation), C group (bacteria inoculation group), D group (control). The animals were examined by the methods of endoscope, histology and bacteriology after two weeks.


RESULTS
The success rate of model were 60% (A group), 100% (B group) and 0% (C,D group). Both maxillary sinus and ethmoid sinus had developed inflammation.


CONCLUSIONS
A rhinogenic model of acute sinusitis can be created by inserting synthetic sponge instilled with pathogenic bacteria into nasal cavity. This is a simple method and has the potential to be valuable to study on FESS.
Wnag
Pengju
P
wangpju@sohu.com
Shen
Yin
Y
D000208:Acute Disease; D000818:Animals; D004195:Disease Models, Animal; D007249:Inflammation; D011817:Rabbits; D012852:Sinusitis