C-C bond formation via double C-H functionalization: aerobic oxidative coupling as a method for synthesizing heterocoupled biaryls.
The aerobic oxidative coupling of arenes such as benzofuran and N-substituted indoles with benzene and derivatives thereof is described. The reaction is shown to take place in both inter- and intramolecular scenarios.
Dwight
Timothy A
TA
Department of Chemistry, University of Rhode Island, Kingston, Rhode Island 02881, USA.
Rue
Nicholas R
NR
Charyk
Dagmara
D
Josselyn
Ryan
R
DeBoef
Brenton
B
D001572:Benzofurans / Q000138:chemical synthesis / Q000737:chemistry*; D020650:Combinatorial Chemistry Techniques; D006571:Heterocyclic Compounds / Q000138:chemical synthesis* / Q000737:chemistry*; D007211:Indoles / Q000737:chemistry*; D015394:Molecular Structure; D010084:Oxidation-Reduction
D001572:Benzofurans; D006571:Heterocyclic Compounds; D007211:Indoles