title: Trust and experience as predictors of HPV vaccine acceptance.
abstract: BACKGROUND
  Awareness of factors associated with uptake of new childhood vaccinations could help physicians focus attention on parents who are most likely to decline to help and ensure that they are fully informed before making a vaccination decision.
  
  
  OBJECTIVE
  To examine the association between general vaccine attitudes, trust in doctors and the government, past experience with vaccination, and acceptance of HPV vaccination.
  
  
  METHODS
  School-based survey.
  
  
  METHODS
  Questionnaires were sent through 10 schools in England.
  
  
  METHODS
  Questionnaires were sent to 1205 mothers of 8-14 year old girls. Responses from 684 mothers were included in analyses.
  
  
  METHODS
  Intended acceptance of prophylactic HPV vaccination.
  
  
  RESULTS
  Mothers who had high trust in doctors or the government were more likely to accept the vaccine (OR = 1.35, CI: 1.22-1.50), as were those who believed their own doctor would take their vaccine concerns seriously (OR = 1.70, CI: 1.23-2.36). Mothers who had delayed (OR = 0.31, CI: 0.19-0.51), refused (OR = 0.33, CI: 0.18-0.59), or regretted (OR = 0.43, CI: 0.19-0.99) a previous paediatric vaccination were less likely to accept the HPV vaccine. The child having experienced adverse effects from a previous vaccination was not significantly associated with acceptance (OR = 0.48, CI: 0.21-1.10).
  
  
  CONCLUSIONS
  Past experience and trust in doctors and government were associated with differential acceptance of a new vaccine. These results suggest that doctors should listen to parents' worries about vaccination, especially parents who have previously delayed or refused vaccines. It may also be beneficial for health information to emphasize the general importance of vaccination as an effective disease prevention strategy.
authors.affiliation: Cancer Research UK Health Behaviour Unit, Department of Epidemiology and Public Health, UCL, London, UK.
authors.forename: Laura A V
authors.initials: LA
authors.lastname: Marlow
authors.forename: Jo
authors.initials: J
authors.lastname: Waller
authors.forename: Jane
authors.initials: J
authors.lastname: Wardle
mesh_terms: D000293:Adolescent; D000328:Adult; D001294:Attitude to Health; D002648:Child; D004739:England; D005260:Female; D019538:Health Care Surveys; D007722:Health Knowledge, Attitudes, Practice; D006801:Humans; D009035:Mothers / Q000523:psychology; D053918:Papillomavirus Vaccines; D011368:Professional-Family Relations; D011795:Surveys and Questionnaires; D014611:Vaccination / Q000523:psychology*
chemical_list: D053918:Papillomavirus Vaccines