title: [Investigation of the germicidal effect of usnic acid, betadine, savlosol, and desderman on the protoscolexes of lung hydatid cysts].
abstract: Injecting scolicidal agents into the intact hydatid cyst and packing the operative field with sponges soaked in scolicidal agents have been used to avoid dissemination of the parasite into the pleural cavity and bronchial system during surgery. The aim of this study was to determine the scolicidal property of different concentrations and exposure times of various agents on the protoscolexes. For this reason, usnic acid, betadine (%10 povidine iodine), savlosol (15% cetrimide-1.5% chlorhexidine), and desderman (96% ethanol and 2-biphenylol) and their various dilutions were used. Protoscolexes were obtained from lungs containing cysts of the naturally infected sheep and viability was determined by dye-uptake (0.1% Eosin). It was found that usnic acid did not completely kill the scolexes in 15 minutes. Betadine, savlosol, and desderman was strongly germicidal in 15 minutes. Savlosol was found to have a germicidal effect at the lowest concentration among the agents studied.
authors.affiliation: Afyon Kocatepe Universitesi Tip Fakültesi Göğüs Cerrahisi Anabilim Dali, Afyon, Turkey. hesme@aku.edu.tr
authors.forename: Hidir
authors.initials: H
authors.lastname: Esme
authors.forename: Ihsan Hakki
authors.initials: IH
authors.lastname: Ciftçi
authors.forename: Okan
authors.initials: O
authors.lastname: Solak
authors.forename: Osman Nuri
authors.initials: ON
authors.lastname: Dilek
mesh_terms: D000818:Animals; D000890:Anti-Infective Agents / Q000494:pharmacology*; D001572:Benzofurans / Q000494:pharmacology; D000077286:Cetrimonium; D002593:Cetrimonium Compounds / Q000494:pharmacology; D002710:Chlorhexidine / Q000494:pharmacology; D004443:Echinococcosis / Q000469:parasitology / Q000517:prevention & control; D004446:Echinococcus / Q000187:drug effects*; D006801:Humans; D008168:Lung / Q000469:parasitology; D011206:Povidone-Iodine / Q000494:pharmacology
chemical_list: D000890:Anti-Infective Agents; D001572:Benzofurans; D002593:Cetrimonium Compounds; C073339:usnic acid; D011206:Povidone-Iodine; D002710:Chlorhexidine; D000077286:Cetrimonium