title: Dietary intake and urinary excretion of selenium in the Japanese adult population: the INTERMAP Study Japan.
abstract: OBJECTIVE
  This study is to examine the relationship between dietary selenium intake and 24-h urinary selenium excretion in Japanese population samples participating in the INTERMAP Study.
  
  
  METHODS
  Using highly standardized methods, we assessed individual dietary selenium intake from four 24-h dietary recalls and measured urinary selenium excretion in two timed 24-h urine collections in 1145 Japanese participants (574 men and 571 women) ages 40-59 years in four areas of Japan.
  
  
  RESULTS
  The medians of dietary selenium intake were 177.5 microg/day in men and 139.8 microg/day in women; the medians of 24-h urinary selenium excretion were 127.9 microg/day in men and 109.4 microg/day in women, that is, urinary excretion was estimated to be 73% of dietary intake in men and 77% in women. Dietary selenium intake was significantly correlated with 24-h urinary selenium excretion (r=0.24 in men, r=0.18 in women; P<0.001). With dietary selenium intake and urinary selenium excretion expressed per kg of body weight, values were similar for men and women (dietary intake, 2.7 microg/kg body weight in men and 2.5 microg/kg body weight in women; urinary excretion, 2.0 microg/kg body weight in men and 2.0 microg/kg body weight in women).
  
  
  CONCLUSIONS
  Dietary intake and 24-h urinary excretion of selenium are related in the Japanese adult population.
authors.affiliation: Department of Epidemiology and Public Health, Kanazawa Medical University, Ishikawa, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Yoneyama
authors.forename: K
authors.initials: K
authors.lastname: Miura
authors.forename: K
authors.initials: K
authors.lastname: Itai
authors.forename: K
authors.initials: K
authors.lastname: Yoshita
authors.forename: H
authors.initials: H
authors.lastname: Nakagawa
authors.forename: T
authors.initials: T
authors.lastname: Shimmura
authors.forename: A
authors.initials: A
authors.lastname: Okayama
authors.forename: K
authors.initials: K
authors.lastname: Sakata
authors.forename: S
authors.initials: S
authors.lastname: Saitoh
authors.forename: H
authors.initials: H
authors.lastname: Ueshima
authors.forename: P
authors.initials: P
authors.lastname: Elliott
authors.forename: J
authors.initials: J
authors.lastname: Stamler
mesh_terms: D000328:Adult; D015415:Biomarkers / Q000652:urine; D003430:Cross-Sectional Studies; D004032:Diet; D005260:Female; D006801:Humans; D007564:Japan / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D009749:Nutrition Surveys; D011159:Population Surveillance; D012643:Selenium / Q000008:administration & dosage* / Q000652:urine*; D017678:Sex Distribution; D013997:Time Factors
chemical_list: D015415:Biomarkers; D012643:Selenium