Redox-modulated recognition of tetrazines using thioureas.
Reduced 1,2,4,5-tetrazines serve as two-point hydrogen-bonding acceptors for thiourea. This host-guest system does not exhibit significant binding in the neutral state, making the complex an electrochemical "on/off" switch.
Jordan
Brian J
BJ
Department of Chemistry, University of Massachusetts, Amherst, Massachusetts 01003, USA. rotello@chem.umass.edu
Pollier
Michael A
MA
Miller
Luke A
LA
Tiernan
Christopher
C
Clavier
Gilles
G
Audebert
Pierre
P
Rotello
Vincent M
VM