title: Moxibustion, an alternative therapy, ameliorated disturbed circadian rhythm of plasma arginine vasopressin and urine output in multiple system atrophy.
abstract: Previously no alternative therapy approach has been made to ameliorate disturbed circadian arginine vasopressin rhythm (C-AVP-R) in multiple system atrophy (MSA). A 65-year-old man with MSA showed loss of C-AVP-R and nocturnal polyuria. We performed moxibustion at specific acupuncture points on the bladder and inside the feet, once a day, 3 times a week, for 6 months. After the treatment, his C-AVP-R appeared to be normal, and the nocturnal urine output decreased to 75% (p<0.01). Together with the previous studies, it seems possible that somatic warm stimulation by moxibustion in specific points might have facilitated AVP secretion in this patient.
authors.affiliation: Department of Neurology, Chiba University. sakakibara@faculty.chiba-u.jp
authors.forename: Ryuji
authors.initials: R
authors.lastname: Sakakibara
authors.forename: Eiko
authors.initials: E
authors.lastname: Murakami
authors.forename: Akira
authors.initials: A
authors.lastname: Katagiri
authors.forename: Sei
authors.initials: S
authors.lastname: Hayakawa
authors.forename: Tomoyuki
authors.initials: T
authors.lastname: Uchiyama
authors.forename: Tatsuya
authors.initials: T
authors.lastname: Yamamoto
authors.forename: Takamichi
authors.initials: T
authors.lastname: Hattori
mesh_terms: D000368:Aged; D001127:Arginine Vasopressin / Q000097:blood* / Q000378:metabolism; D002940:Circadian Rhythm; D000529:Complementary Therapies / Q000379:methods*; D005500:Follow-Up Studies; D006801:Humans; D007564:Japan; D008297:Male; D009071:Moxibustion / Q000379:methods*; D019578:Multiple System Atrophy / Q000175:diagnosis / Q000628:therapy*; D053206:Nocturnal Enuresis / Q000175:diagnosis / Q000628:therapy; D011141:Polyuria / Q000175:diagnosis / Q000628:therapy*; D018570:Risk Assessment; D016896:Treatment Outcome
chemical_list: D001127:Arginine Vasopressin