Amphidinolactone B, a new 26-membered macrolide from dinoflagellate Amphidinium sp.
A new 26-membered macrolide, amphidinolactone B, has been isolated from a marine dinoflagellate Amphidinium sp., and the structure and relative stereochemistry were elucidated on the basis of spectroscopic data. Amphidinolactone B (1) showed modest cytotoxicity.
Takahashi
Yohei
Y
Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan.
Kubota
Takaaki
T
Kobayashi
Jun'ichi
J
D000818:Animals; D000970:Antineoplastic Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D004141:Dinoflagellida / Q000737:chemistry*; D004354:Drug Screening Assays, Antitumor; D018942:Macrolides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D008968:Molecular Conformation; D019906:Nuclear Magnetic Resonance, Biomolecular; D021241:Spectrometry, Mass, Electrospray Ionization; D013055:Spectrophotometry, Infrared
D000970:Antineoplastic Agents; D018942:Macrolides