[Collective poliomyelitis immunity in the adult population and its impact on eradication of this infection].
Collective poliomyelitis immunity was studied in 6339 donors from 19 towns and cities of Russia. Its stress substantially varied in different towns and cities. Studies of strain-specific antibodies to vaccine and wild viruses of poliomyelitis in donors from 4 towns established that the immune persons were more in the town where wild polioviruses had previously circulated than in those where the circulation of wild polioviruses had been limited and immunity resulted from vaccination. Circulation of vaccine viruses and reversion of their neurovirulent properties should be expected in the town where there are low collective poliomyelitis immunity rates. It is concluded that it is impossible to eradicate poliomyelitis as infection today; it is possible only to eliminate the disease if further vaccination of children is performed with live poliomyelitis vaccine.
Seĭbil'
V B
VB
Malyshkina
L P
LP
Lavrova
I K
IK
Efimova
V F
VF
D000293:Adolescent; D000328:Adult; D000368:Aged; D000914:Antibodies, Viral / Q000097:blood* / Q000276:immunology; D000918:Antibody Specificity; D005260:Female; D006801:Humans; D017589:Immunization Programs; D008297:Male; D008875:Middle Aged; D011051:Poliomyelitis / Q000097:blood / Q000209:etiology / Q000517:prevention & control*; D017955:Poliovirus / Q000276:immunology*; D011055:Poliovirus Vaccine, Oral / Q000008:administration & dosage / Q000276:immunology*; D023321:Poliovirus Vaccines / Q000009:adverse effects / Q000276:immunology*; D012307:Risk Factors; D012426:Russia / Q000453:epidemiology; D016036:Seroepidemiologic Studies; D014019:Tissue Donors; D014505:Urban Population; D014611:Vaccination / Q000009:adverse effects / Q000379:methods
D000914:Antibodies, Viral; D011055:Poliovirus Vaccine, Oral; D023321:Poliovirus Vaccines