Chemical constituents of the leaves of Diospyros kaki and their cytotoxic effects.
Isolation and structure elucidation of two new compounds, kakispyrone (1) and kakisaponin A (2), together with 11 known compounds, from the leaves of Diospyros kaki L. are described. Their cytotoxic effects against several cancer cell lines (A549, HepG2 and HT29) are also reported.
Chen
G
G
Department of Biological Science and Biotechnology, Beijing University of Chemical Technology, Beijing 100029, China. chenguang@mail.buct.edu.cn
Xue
J
J
Xu
S-X
SX
Zhang
R-Q
RQ
D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D001577:Benzophenones / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D045744:Cell Line, Tumor; D029788:Diospyros / Q000737:chemistry*; D005960:Glucosides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D018515:Plant Leaves / Q000737:chemistry*; D012503:Saponins / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
C525307:4,6-dihydroxy-2-O-glucopyranosylbenzophenone; D000972:Antineoplastic Agents, Phytogenic; D001577:Benzophenones; D005960:Glucosides; D012503:Saponins; C525308:kakisaponin A