title: Syringomyelia and chronic respiratory failure in a term infant delivered by Caesarean section.
abstract: The case of a term, male neonate (birthweight 3785g) with cephalic presentation, Caesarean-section (C-section) delivery, and failure to thrive is reported. The infant presented with generalized hypotonia and respiratory failure immediately following birth. An initial diagnosis of hypoxic-ischemic encephalopathy was made. However, ventilator dependency and slow recovery of generalized tonus over the following weeks could not be explained. Late cervical magnetic resonance imaging showed extensive syringomyelia from C2 to C7. To the authors' knowledge, this is the first report of syringomyelia after a C-section delivery following cephalic presentation without any associated abnormalities. Follow-up at 2 years of age revealed no improvement on neurological examination: poor head control, difficulty swallowing, flaccid paralysis of upper limbs, and spasticity of lower limbs with exacerbated deep reflexes and spontaneous clonus. Difficulties in establishing the diagnosis and managing the case are discussed.
authors.affiliation: McMaster Children's Hospital, 1200 Main Street West, Hamilton, Ontario, Canada. santang@mcmaster.ca
authors.forename: G M
authors.initials: GM
authors.lastname: Sant'Anna
authors.forename: C T
authors.initials: CT
authors.lastname: Azevedo
authors.forename: A
authors.initials: A
authors.lastname: Simas
authors.forename: B P
authors.initials: BP
authors.lastname: Castro
authors.forename: C A
authors.initials: CA
authors.lastname: Bhering
mesh_terms: D002585:Cesarean Section / Q000009:adverse effects*; D002675:Child, Preschool; D005500:Follow-Up Studies; D006801:Humans; D007231:Infant, Newborn; D008279:Magnetic Resonance Imaging; D008297:Male; D012131:Respiratory Insufficiency / Q000209:etiology*; D013595:Syringomyelia / Q000209:etiology* / Q000473:pathology