title: Developmental expression of amphioxus RACK1.
abstract: Vertebrate RACK1 plays a key role in embryonic development. This paper described the cloning, phylogenetic analysis and developmental expression of AmphiRACK1, the RACK1 homologous gene in amphioxus. Phylogenetic analysis indicated that amphioxus RACK1 was located at the base of vertebrate clade. AmphiRACK1 expression in lithium-treated embryos was also examined. During embryonic development, AmphiRACK1 was expressed strongly in cerebral vesicles, neural tubes and somites. In lithium-treated embryos, the segmental expression of AmphiRACK1 in somites became blurry and decreased. Its expression in cerebral vesicles and neural tubes was also weaker or disappeared. In the adult animal, AmphiRACK1 transcripts were detected in the epithelium of midgut diverticulus and gut, wheel organ, gill blood vessels and testis.
authors.affiliation: Institute of Developmental Biology, College of Life Science, China.
authors.forename: XiangWei
authors.initials: X
authors.lastname: Huang
authors.forename: Wei
authors.initials: W
authors.lastname: Zhang
authors.forename: XinYi
authors.initials: X
authors.lastname: Li
authors.forename: XiaoHui
authors.initials: X
authors.lastname: Zhang
authors.forename: BaoJun
authors.initials: B
authors.lastname: Li
authors.forename: BingYu
authors.initials: B
authors.lastname: Mao
authors.forename: HongWei
authors.initials: H
authors.lastname: Zhang
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D002816:Chordata, Nonvertebrate / Q000145:classification / Q000201:enzymology* / Q000235:genetics / Q000254:growth & development; D017124:Conserved Sequence; D018507:Gene Expression Regulation, Developmental; D015971:Gene Expression Regulation, Enzymologic; D006801:Humans; D007814:Larva / Q000201:enzymology; D008969:Molecular Sequence Data; D010802:Phylogeny; D000075370:Receptors for Activated C Kinase; D011956:Receptors, Cell Surface / Q000235:genetics*; D016415:Sequence Alignment; D017386:Sequence Homology, Amino Acid; D014714:Vertebrates
chemical_list: D000075370:Receptors for Activated C Kinase; D011956:Receptors, Cell Surface