Diastereo- and enantioselective synthesis of alpha,beta-epoxyketones using aqueous NaOCl in conjunction with dihydrocinchonidine derived phase-transfer catalysis at room temperature. Scope and limitations.
In this paper we present studies into the scope and limitations of asymmetric PTC epoxidation of enones and the oxidation-epoxidation of allylic alcohols using aqueous NaOCl in conjunction with a dihydrocinchonidine derived quaternary ammonium salt catalyst.
Lygo
Barry
B
School of Chemistry, University of Nottingham, Nottingham, UK NG7 2RD.
Gardiner
Stuart D
SD
McLeod
Michael C
MC
To
Daniel C M
DC