Retroperitoneal liposarcoma associated with small plaque parapsoriasis.
BACKGROUND
Extremely rare cases of paraneoplastic syndromes or ectopic production of proteins associated with liposarcoma are reported in literature. Production of Granulocyte-Colony Stimulating Factor, alpha-fetoprotein, paraneoplastic pemphigus and leucocytosis, Acrokeratosis paraneoplastica (Bazex's syndrome) are reported. The present report describes a case of retroperitoneal liposarcoma associated with small plaque parapsoriasis. Our search in the English literature of such a kind of association did not reveal any case reported.


METHODS
A 74 year male patient was admitted to our hospital because of the presence of an abdominal mass in right iliac fossa. He also complained of a two-year history of psoriasiform eruptions. The CT scan showed a retroperitoneal pelvic mass. Therefore surgical resection of the tumor was performed. After surgery, the skin eruptions disappeared completely in seven days and so a diagnosis of parapsoriasis syndrome was done.


CONCLUSIONS
Parallel disappearing of skin eruptions after surgery, typical clinical picture and not specific histology of the cutaneous lesions suggest the diagnosis of small plaque parapsoriasis. Therefore we propose to add Small Plaque Parapsoriasis to the list of paraneoplastic syndromes associated to liposarcoma.
Tartaglia
Francesco
F
Department of Surgical Sciences, La Sapienza University, viale Regina Elena 324, 00161 Rome, Italy. francesco.tartaglia@uniroma1.it
Blasi
Sara
S
Sgueglia
Monica
M
Polichetti
Paolo
P
Tromba
Luciana
L
Berni
Alberto
A
D000368:Aged; D006801:Humans; D008080:Liposarcoma / Q000150:complications* / Q000473:pathology / Q000601:surgery; D008297:Male; D010257:Paraneoplastic Syndromes / Q000150:complications* / Q000473:pathology; D010267:Parapsoriasis / Q000150:complications* / Q000473:pathology; D012186:Retroperitoneal Neoplasms / Q000150:complications* / Q000473:pathology / Q000601:surgery