[Chemicotoxicological evaluation of doxylamine].
The conditions of doxilamine isolation from biological fluids are studied. The method of its extraction with a mixture of organic solvents in pH 9 is proposed. Identification of doxilamine with techniques of thin layer chromatography, UV-, IR-spectroscopy, chromato-mass-spectrometry, densitometry, gas-liquid chromatography is described. UV-spectrometry, gas chromatography and densitometry can be used for quantitation of doxilamine.
Kireeva
A V
AV
Vozheva
A B
AB
Bakhtina
S M
SM
Volchenko
S V
SV
Kuklin
V N
VN
D000818:Animals; D004319:Doxylamine / Q000032:analysis* / Q000097:blood / Q000652:urine; D053593:Forensic Toxicology / Q000379:methods*; D006801:Humans; D006993:Hypnotics and Sedatives / Q000032:analysis* / Q000097:blood / Q000652:urine; D051379:Mice; D004364:Pharmaceutical Preparations / Q000737:chemistry / Q000592:standards; D051381:Rats; D012997:Solvents / Q000737:chemistry; D015813:Substance Abuse Detection / Q000379:methods*; D013607:Tablets
D006993:Hypnotics and Sedatives; D004364:Pharmaceutical Preparations; D012997:Solvents; D013607:Tablets; D004319:Doxylamine