title: Alterations in the physiology of growth of cattle with growth-enhancing compounds.
abstract: Commonly used growth promotants such as steroidal implants and beta-adrenergic agonists have recently been implicated in the reduction of marbling scores in beef cattle. These compounds are effective at improving lean tissue deposition in cattle, thus significantly improving feed efficiency. This article discusses skeletal muscle growth and development in cattle, the process of transdifferentiation between two cell types, and how growth promotants may push a nondifferentiated cell to become a certain lineage of cells. Increased understanding of how these agents affect cellular aspects of growth and development of skeletal muscle and adipose tissue will allow cattle feeders, consultants, and researchers to instigate intervention strategies to ameliorate the reduced marbling scores. Successful strategies would allow maximal lean tissue growth and result in carcasses with optimal quality.
authors.affiliation: Nutritional Growth and Development, Department of Animal Sciences and Industry, Kansas State University, Manhattan, KS 66506-1600, USA. bjohnson@ksu.edu
authors.forename: Bradley J
authors.initials: BJ
authors.lastname: Johnson
authors.forename: Ki Yong
authors.initials: KY
authors.lastname: Chung
mesh_terms: D045930:Anabolic Agents / Q000008:administration & dosage* / Q000009:adverse effects; D000822:Animal Husbandry / Q000379:methods*; D000818:Animals; D001823:Body Composition / Q000187:drug effects; D002417:Cattle / Q000254:growth & development*; D004343:Drug Implants / Q000008:administration & dosage* / Q000009:adverse effects; D006801:Humans; D008460:Meat / Q000592:standards*; D018482:Muscle, Skeletal / Q000187:drug effects / Q000254:growth & development / Q000378:metabolism; D011786:Quality Control
chemical_list: D045930:Anabolic Agents; D004343:Drug Implants