Nine acetylenic alcohols isolated from the Okinawan marine sponge of the genus Petrosia (Strongylophora).
Nine new acetylenic alcohols 1-9 were isolated from a marine sponge belonging to the genus Petrosia (Strongylophora). The structures were elucidated mainly based on the analysis of one-and two-dimensional NMR spectral data. To determine the position of the central double bonds in 1-8, each compound was cleaved with OsO(4) and HIO(4), and the resulting aldehyde was converted to the corresponding 2,4-dinitrophenylhydrazone. Analysis of the high-resolution mass and (13)C NMR spectral data of each 2,4-dinitrophenylhydrazone clarified the position of the central double bonds in 1-8.
Watanabe
Kinzo
K
School of Life Sciences, Tokyo University of Pharmacy and Life Science, Tokyo 192-0392, Japan. kinzo@ls.toyaku.ac.jp
Mori
Go
G
Iguchi
Kazuo
K
Suzuki
Motoya
M
Van Soest
Rob W M
RW
D000438:Alcohols / Q000737:chemistry / Q000302:isolation & purification*; D000818:Animals; D007564:Japan; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D009993:Osmium Tetroxide / Q000737:chemistry; D010504:Periodic Acid / Q000737:chemistry; D047130:Petrosia / Q000737:chemistry*; D010659:Phenylhydrazines / Q000737:chemistry; D053279:Polyynes / Q000737:chemistry / Q000302:isolation & purification*; D021241:Spectrometry, Mass, Electrospray Ionization; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet
D000438:Alcohols; D010659:Phenylhydrazines; D010504:Periodic Acid; C004787:2,4-dinitrophenylhydrazine; D053279:Polyynes; D009993:Osmium Tetroxide