title: Estimation of predictive accuracy in survival analysis using R and S-PLUS.
abstract: When the purpose of a survival regression model is to predict future outcomes, the predictive accuracy of the model needs to be evaluated before practical application. Various measures of predictive accuracy have been proposed for survival data, none of which has been adopted as a standard, and their inclusion in statistical software is disregarded. We developed the surev library for R and S-PLUS, which includes functions for evaluating the predictive accuracy measures proposed by Schemper and Henderson. The library evaluates the predictive accuracy of parametric regression models and of Cox models. The predictive accuracy of the Cox model can be obtained also when time-dependent covariates are included because of non-proportional hazards or when using Bayesian model averaging. The use of the library is illustrated with examples based on a real data set.
authors.affiliation: Department of Experimental Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Italy. lara.lusa@ifom-ieo-campus.it
authors.forename: Lara
authors.initials: L
authors.lastname: Lusa
authors.forename: Rosalba
authors.initials: R
authors.lastname: Miceli
authors.forename: Luigi
authors.initials: L
authors.lastname: Mariani
mesh_terms: D003627:Data Interpretation, Statistical; D011381:Programming Languages; D016016:Proportional Hazards Models; D015203:Reproducibility of Results; D018570:Risk Assessment / Q000379:methods*; D012307:Risk Factors; D012680:Sensitivity and Specificity; D012984:Software; D016019:Survival Analysis