title: Missed opportunities for prevention of mother-to-child transmission of human immunodeficiency virus type 1 in Latin America and the Caribbean: the NISDI perinatal study.
abstract: Cases of mother-to-child transmission (MTCT) of human immunodeficiency virus type 1 (HIV-1) in a prospective cohort study in Latin America and the Caribbean were analyzed. Eight of 820 eligible infants became infected [transmission rate, 0.98% (95% CI = 0.45-1.96%)]. Five cases (62%) represented missed opportunities for prevention of MTCT of HIV-1, suggesting the need for ongoing training and education of clinicians regarding prevention of MTCT of HIV-1.
authors.affiliation: Hospital dos Servidores do Estado, Rio de Janeiro, Brazil.
authors.forename: Marcos
authors.initials: M
authors.lastname: D'Ippolito
authors.forename: Jennifer S
authors.initials: JS
authors.lastname: Read
authors.forename: James
authors.initials: J
authors.lastname: Korelitz
authors.forename: Esau Custódio
authors.initials: EC
authors.lastname: João
authors.forename: Marisa
authors.initials: M
authors.lastname: Mussi-Pinhata
authors.forename: Neiva
authors.initials: N
authors.lastname: Rocha
mesh_terms: D000328:Adult; D019380:Anti-HIV Agents / Q000008:administration & dosage* / Q000627:therapeutic use*; D017691:Caribbean Region / Q000453:epidemiology; D015331:Cohort Studies; D005260:Female; D015658:HIV Infections / Q000635:transmission*; D015497:HIV-1; D006801:Humans; D007231:Infant, Newborn; D018445:Infectious Disease Transmission, Vertical / Q000517:prevention & control*; D007843:Latin America / Q000453:epidemiology; D011247:Pregnancy
chemical_list: D019380:Anti-HIV Agents