title: [Postmortem changes of liver phosphofructokinase-2 level in rats following different causes of death].
abstract: OBJECTIVE
  To study the changes of liver phosphofructokinase-2 (PFK-2) level at different postmortem intervals as well as due to different causes of death.
  
  
  METHODS
  One hundred and five rats were randomly divided into 3 groups and the rats were sacrificed by either bleeding, suffocating, and neck breaking, respectively. The content of liver PFK-2 at 0, 1, 2, 4, 8, 12 and 24 hours following death were studied using immunohistochemishtry and image analysis.
  
  
  RESULTS
  PFK-2 content of the rat's liver in all 3 groups showed a linear decrease at different postmortem intervals with no significant statistical differences found between the different groups.
  
  
  CONCLUSIONS
  PFK-2 level in rat liver appears to decrease linearly in correlation with prolonged PMI.
authors.affiliation: West China School of Preclinical and Forensic Medicine, Sichuan University, Chengdu 610041, China.
authors.forename: Ju
authors.initials: J
authors.lastname: Jin
authors.forename: Bin
authors.initials: B
authors.lastname: Li
authors.forename: Bai-Guang
authors.initials: BG
authors.lastname: Jiao
authors.forename: Jia
authors.initials: J
authors.lastname: Fu
authors.forename: Hong
authors.initials: H
authors.lastname: Huang
authors.forename: Yu
authors.initials: Y
authors.lastname: Song
authors.forename: Qi-Yi
authors.initials: QY
authors.lastname: Peng
authors.forename: Zhi-Gang
authors.initials: ZG
authors.lastname: Liao
mesh_terms: D000818:Animals; D001237:Asphyxia / Q000378:metabolism; D002423:Cause of Death; D002574:Cervical Vertebrae / Q000293:injuries; D005260:Female; D007150:Immunohistochemistry; D008099:Liver / Q000201:enzymology*; D008297:Male; D025481:Phosphofructokinase-2 / Q000378:metabolism*; D011180:Postmortem Changes; D011897:Random Allocation; D051381:Rats; D017207:Rats, Sprague-Dawley; D012771:Shock, Hemorrhagic / Q000378:metabolism; D013194:Staining and Labeling; D013997:Time Factors
chemical_list: D025481:Phosphofructokinase-2