title: Assessment of global left ventricular functional parameters: analysis of every second short-axis Magnetic Resonance Imaging slices is as accurate as analysis of consecutive slices.
abstract: The purpose of this study was to assess whether accurate global left-ventricular (LV) functional parameters can be obtained by analyzing every second short-axis magnetic resonance imaging cine series instead of consecutive slices, in order to reduce post-processing time. Forty patients, were scanned on a 1.5 T MRI-system (Magnetom Sonata, Siemens Medical Systems, Erlangen, Germany) using a steady-state free precession (SSFP) sequence. A stack of short-axis cine series from above the mitral valve through the apex was acquired. Post-processing was started at the most basal slice of the left ventricle, in which at least 50% of the circumference was myocardium. End-diastolic volume (EDV), end-systolic volume (ESV), stroke volume (SV), ejection fraction (EF) and LV mass (LVM), were calculated. Data analysis was repeated, but now only every second slice was analyzed. Bland-Altman analysis showed slightly lower values for all LV parameters when only every second slice was analyzed, ranging from 1.7% difference for EF (limits of agreement -3.5 to 5.0) to 4.6% for SV (limits of agreement -7.2 to 15.0). Analysis of every second slice for quantification of global LV function is time-saving and as accurate as analysis of consecutive slices.
authors.affiliation: Department of Radiology, University Medical Center Groningen, University of Groningen, Hanzeplein 1, 9700 RB, Groningen, The Netherlands. d.d.lubbers@rad.umcg.nl
authors.forename: Daniel D
authors.initials: DD
authors.lastname: Lubbers
authors.forename: Tineke P
authors.initials: TP
authors.lastname: Willems
authors.forename: Pieter A
authors.initials: PA
authors.lastname: van der Vleuten
authors.forename: Jelle
authors.initials: J
authors.lastname: Overbosch
authors.forename: Marco J W
authors.initials: MJ
authors.lastname: Götte
authors.forename: Dirk J
authors.initials: DJ
authors.lastname: van Veldhuisen
authors.forename: Matthijs
authors.initials: M
authors.lastname: Oudkerk
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D007090:Image Interpretation, Computer-Assisted; D019028:Magnetic Resonance Imaging, Cine / Q000379:methods*; D008297:Male; D008875:Middle Aged; D018487:Ventricular Dysfunction, Left / Q000175:diagnosis*