title: Acute bacterial meningitis in HIV, patients in southern Brazil: Curitiba, Paraná, Brazil.
abstract: Acute communitarian bacterial meningitis and AIDS are prevalent infectious disease in Brazil. The objective of this study was to evaluate the frequency of acute communitarian bacterial meningitis in AIDS patients, the clinical and cerebrospinal fluid (CSF) characteristics. It was reviewed the Health Department data from city of Curitiba, Southern Brazil, from 1996 to 2002. During this period, 32 patients with AIDS fulfilled criteria for acute bacterial meningitis, representing 0.84% of the AIDS cases and 1.85% of the cases of bacterial meningitis. S. pneumoniae was the most frequent bacteria isolated. The number of white blood cells and the percentage of neutrophils were higher and CSF glucose was lower in the group with no HIV co-infection (p 0.12; 0.008; 0.04 respectively). Bacteria not so common causing meningitis can occur among HIV infected patients. The high mortality rate among pneumococcus meningitis patients makes pneumococcus vaccination important.
authors.affiliation: Virology Unit, Clinical Analysis Laboratory, Hospital de Clínicas, Federal University of Paraná, Brazil. sergio.ma@pop.com.br
authors.forename: Sérgio M de
authors.initials: SM
authors.lastname: Almeida
authors.forename: Jorge A
authors.initials: JA
authors.lastname: Zavala
authors.forename: George
authors.initials: G
authors.lastname: Savalla
authors.forename: Betina Mendez A
authors.initials: BM
authors.lastname: Gabardo
authors.forename: Clea Elisa
authors.initials: CE
authors.lastname: Ribeiro
authors.forename: Andrea M
authors.initials: AM
authors.lastname: Rossoni
authors.forename: Josiane M R
authors.initials: JM
authors.lastname: Araújo
mesh_terms: D000208:Acute Disease; D000328:Adult; D001938:Brazil / Q000453:epidemiology; D017714:Community-Acquired Infections / Q000382:microbiology; D005260:Female; D015658:HIV Infections / Q000453:epidemiology / Q000382:microbiology*; D018023:HIV Seronegativity; D006801:Humans; D008297:Male; D016920:Meningitis, Bacterial / Q000134:cerebrospinal fluid / Q000150:complications* / Q000401:mortality; D008586:Meningitis, Pneumococcal / Q000401:mortality; D022242:Pneumococcal Vaccines / Q000627:therapeutic use; D012189:Retrospective Studies; D012307:Risk Factors; D018709:Statistics, Nonparametric; D013296:Streptococcus pneumoniae / Q000302:isolation & purification
chemical_list: D022242:Pneumococcal Vaccines