title: The short PET in pediatrics.
abstract: BACKGROUND
  The peritoneal equilibration test (PET) is a 4-hour procedure that is recommended to be performed in children receiving peritoneal dialysis to assist in prescription management. While a shortened version of the PET has been used in adults and reliably characterizes peritoneal membrane transport capacity, no similar experience with children has been reported.
  
  
  METHODS
  Retrospective evaluation of 2-hour and 4-hour PET data obtained from 20 children receiving chronic peritoneal dialysis in a single center. Characterization of membrane transport capacity was based on evaluation of serum and dialysate samples used to determine the dialysate-to-plasma ratio (D/P) of creatinine and the ratio of dialysate glucose to baseline dialysate glucose (D/D(0)). Patient values were compared to pediatric reference data.
  
  
  RESULTS
  In all 20 patients, characterization of peritoneal membrane transport capacity using 2-hour D/P and D/D(0) results was identical to that determined using 4-hour data for the same solute. While the creatinine- and glucose-based characterization was discrepant in 14 of 20 patients, in only 1 case was the discrepancy of more than a single transport category.
  
  
  CONCLUSIONS
  These results support the accuracy of a short PET in children, a procedure that should prove beneficial in terms of patient and staff time.
authors.affiliation: Children's Mercy Hospitals and Clinics, Kansas City, Missouri 64108, USA. bwarady@cmh.edu
authors.forename: Bradley A
authors.initials: BA
authors.lastname: Warady
authors.forename: Janelle
authors.initials: J
authors.lastname: Jennings
mesh_terms: D000293:Adolescent; D001693:Biological Transport, Active / Q000502:physiology; D002648:Child; D002675:Child, Preschool; D003404:Creatinine / Q000097:blood; D015314:Dialysis Solutions / Q000493:pharmacokinetics*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D007676:Kidney Failure, Chronic / Q000378:metabolism / Q000628:therapy*; D008297:Male; D010530:Peritoneal Dialysis / Q000379:methods*; D010537:Peritoneum / Q000378:metabolism*; D011379:Prognosis; D012189:Retrospective Studies; D013997:Time Factors
chemical_list: D015314:Dialysis Solutions; D003404:Creatinine