title: Serum prolidase activity in patients with hypertension and its relation with left ventricular hypertrophy.
abstract: OBJECTIVE
  The purpose of this study was to determine serum prolidase activity in patients with hypertension and its relation with left ventricular hypertrophy.
  
  
  METHODS
  Serum prolidase activity was measured spectrophotometrically in hypertensive patients with (Group II, n=30) and without left ventricular hypertrophy (Group III, n=30) and in control group (Group I, n=30).
  
  
  RESULTS
  Prolidase activity was significantly lower in Group I than in Groups II and III (44.64+/-6.42 U/L vs. 54.14+/-6.30 U/L and 54.25+/-7.14 U/L, respectively; ANOVA, p<0.001). We revealed significant correlation between prolidase activity and presence and duration of hypertension (both of p<0.05) but not left ventricular mass index. Multivariate analysis shown that prolidase activity was significantly associated with age (beta=0.481, p<0.001) and duration of hypertension (beta=0.396, p<0.001).
  
  
  CONCLUSIONS
  Our data show that serum prolidase activity is associated with the presence hypertension independent of left ventricular hypertrophy.
authors.affiliation: Department of Cardiology, Medical Faculty, Harran University, Sanliurfa, Turkiye, P.K: 112, Sanliurfa, Turkey. rdemirbag@yahoo.com
authors.forename: Recep
authors.initials: R
authors.lastname: Demirbag
authors.forename: Ali
authors.initials: A
authors.lastname: Yildiz
authors.forename: Mustafa
authors.initials: M
authors.lastname: Gur
authors.forename: Remzi
authors.initials: R
authors.lastname: Yilmaz
authors.forename: Kevser
authors.initials: K
authors.lastname: Elçi
authors.forename: Nurten
authors.initials: N
authors.lastname: Aksoy
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D004150:Dipeptidases / Q000097:blood* / Q000378:metabolism; D005260:Female; D006801:Humans; D006973:Hypertension / Q000097:blood* / Q000378:metabolism; D017379:Hypertrophy, Left Ventricular / Q000097:blood* / Q000378:metabolism; D008297:Male; D008875:Middle Aged; D013053:Spectrophotometry
chemical_list: D004150:Dipeptidases; C022449:proline dipeptidase