title: Unusual abdominal findings of all-trans-retinoic acid syndrome: role of diagnostic imaging.
abstract: The standard therapy for patients affected by acute promyelocytic leukemia is based on all-trans-retinoic acid (ATRA), whose rare complication is a syndrome known as retinoic acid syndrome. We describe for the first time the computed tomography findings of a case of ATRA syndrome with typical pulmonary findings, along with the involvement of the upper abdomen organs (liver and spleen) as a further complication of the pathology.
authors.affiliation: Istituto di Radiologia, Università di Pavia, Fondazione IRCCS Policlinico S. Matteo, Pavia, Italy. a.lafianza@smatteo.pv.it
authors.forename: Alfredo
authors.initials: A
authors.lastname: La Fianza
authors.forename: Maurizio
authors.initials: M
authors.lastname: Bonfichi
authors.forename: Maria Sole Prevedoni
authors.initials: MS
authors.lastname: Gorone
authors.forename: Anna
authors.initials: A
authors.lastname: Gallotti
authors.forename: Lorella
authors.initials: L
authors.lastname: Torretta
mesh_terms: D000005:Abdomen / Q000000981:diagnostic imaging* / Q000473:pathology*; D000208:Acute Disease; D000328:Adult; D017809:Fatal Outcome; D006801:Humans; D015473:Leukemia, Promyelocytic, Acute / Q000150:complications* / Q000188:drug therapy*; D008297:Male; D013577:Syndrome; D014212:Tretinoin / Q000009:adverse effects* / Q000627:therapeutic use*; D014463:Ultrasonography
chemical_list: D014212:Tretinoin