title: [Comparison of angiofluorography and Heidelberg II retinal tomography of the head of the optic nerve in patients with primary open-angle glaucoma].
abstract: OBJECTIVE
  This prospective study aims to evaluate how the vascular involvement of the optic disc, emphasised by angiofluorography (AFG), correlates with morphologic lesions observed by Heidelberg retinal tomography (HRT) II.
  
  
  METHODS
  AFG (Visucam Zeiss) and HRT II (with Moorfields regression and keratometry) have been performed on the study group -50 pts. with POAG- and in the control group -25 healthy subjects. Correlations have been calculated with Student (t) and Fisher tests. The value of p<0,05 was considered statistically significant.
  
  
  CONCLUSIONS
  The number and size of hypo-fluorescent areas are significantly bigger in POAG pts. than in healthy subjects. They correlate with the involvement of retinal nerve fibers and C/D value. In POAG pts., areas of hypo-fluorescence are located mainly on the excavation's walls and the neuroretinal ring. Localization on the excavation's floor is not pathological, since it was also observed in the control group. The vascular involvement shown by angiofluorography significantly correlates with morphologic lesions observed by HRT II.
authors.affiliation: Spitalul Clinic Universitar de Urgentţă Bucureşti, Clinica de Oftalmologie Sector 5 Bucureşti.
authors.forename: Liliana
authors.initials: L
authors.lastname: Voinea
authors.forename: Daniela Adriana
authors.initials: DA
authors.lastname: Ion
authors.forename: Ana Maria
authors.initials: AM
authors.lastname: Dascălu
authors.forename: Emil
authors.initials: E
authors.lastname: Ungureanu
authors.forename: Aida
authors.initials: A
authors.lastname: Panca
authors.forename: Răzvan Daniel
authors.initials: RD
authors.lastname: Chivu
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003941:Diagnostic Techniques, Ophthalmological; D005260:Female; D005451:Fluorescein Angiography; D005902:Glaucoma, Open-Angle / Q000175:diagnosis*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009898:Optic Disk / Q000473:pathology*; D011446:Prospective Studies; D012680:Sensitivity and Specificity; D012720:Severity of Illness Index; D014054:Tomography