title: Uncomplicated outcome after an accidental overdose of nevirapine in a newborn.
abstract: We report the first case of a massive accidental overdose of nevirapine in a 1-week newborn, due to confusion between nevirapine (Viramune) and nelfinavir (Viracept). The drug was eliminated spontaneously and quickly. We only observed mild neutropenia and hyperlactatemia, which regressed on its own without any clinical complication. Despite the good evolution of this massive overdose, physicians should be aware of confusion risks between some antiretroviral drugs.
authors.affiliation: Assistance Publique-Hôpitaux de Paris, Hôpital Robert-Debré, Pediatric Intensive Care Unit, 48, boulevard Sérurier, 75019 Paris, France.
authors.forename: Jean-François
authors.initials: JF
authors.lastname: Brasme
authors.forename: Frédéric
authors.initials: F
authors.lastname: Mille
authors.forename: Mounir
authors.initials: M
authors.lastname: Benhayoun
authors.forename: Françoise
authors.initials: F
authors.lastname: Bavoux
authors.forename: Albert
authors.initials: A
authors.lastname: Faye
authors.forename: Natacha
authors.initials: N
authors.lastname: Teissier
authors.forename: Eric
authors.initials: E
authors.lastname: Lachassinne
authors.forename: Stéphane
authors.initials: S
authors.lastname: Dauger
mesh_terms: D019380:Anti-HIV Agents / Q000506:poisoning*; D062787:Drug Overdose; D005260:Female; D015658:HIV Infections / Q000188:drug therapy*; D017320:HIV Protease Inhibitors / Q000627:therapeutic use; D006801:Humans; D007231:Infant, Newborn; D008508:Medication Errors; D019888:Nelfinavir / Q000627:therapeutic use; D019829:Nevirapine / Q000506:poisoning*
chemical_list: D019380:Anti-HIV Agents; D017320:HIV Protease Inhibitors; D019829:Nevirapine; D019888:Nelfinavir