Moxibustion, an alternative therapy, ameliorated disturbed circadian rhythm of plasma arginine vasopressin and urine output in multiple system atrophy.
Previously no alternative therapy approach has been made to ameliorate disturbed circadian arginine vasopressin rhythm (C-AVP-R) in multiple system atrophy (MSA). A 65-year-old man with MSA showed loss of C-AVP-R and nocturnal polyuria. We performed moxibustion at specific acupuncture points on the bladder and inside the feet, once a day, 3 times a week, for 6 months. After the treatment, his C-AVP-R appeared to be normal, and the nocturnal urine output decreased to 75% (p<0.01). Together with the previous studies, it seems possible that somatic warm stimulation by moxibustion in specific points might have facilitated AVP secretion in this patient.
Sakakibara
Ryuji
R
Department of Neurology, Chiba University. sakakibara@faculty.chiba-u.jp
Murakami
Eiko
E
Katagiri
Akira
A
Hayakawa
Sei
S
Uchiyama
Tomoyuki
T
Yamamoto
Tatsuya
T
Hattori
Takamichi
T
D000368:Aged; D001127:Arginine Vasopressin / Q000097:blood* / Q000378:metabolism; D002940:Circadian Rhythm; D000529:Complementary Therapies / Q000379:methods*; D005500:Follow-Up Studies; D006801:Humans; D007564:Japan; D008297:Male; D009071:Moxibustion / Q000379:methods*; D019578:Multiple System Atrophy / Q000175:diagnosis / Q000628:therapy*; D053206:Nocturnal Enuresis / Q000175:diagnosis / Q000628:therapy; D011141:Polyuria / Q000175:diagnosis / Q000628:therapy*; D018570:Risk Assessment; D016896:Treatment Outcome
D001127:Arginine Vasopressin