title: Palladium-catalyzed stereoselective formation of alpha-O-glycosides.
abstract: A novel method for palladium-catalyzed stereoselective formation of alpha-O-glycosides has been developed. This strategy relies on the palladium-biaryl phosphine catalyst-glycal donor complexation to control the anomeric selectivity. It does not depend on the nature of the protecting groups on the substrates, thus eliminating the need for cumbersome protecting group manipulations.
authors.affiliation: Department of Chemistry and Biochemistry, Montana State University, Bozeman, Montana 59717, USA.
authors.forename: Brandon P
authors.initials: BP
authors.lastname: Schuff
authors.forename: Gregory J
authors.initials: GJ
authors.lastname: Mercer
authors.forename: Hien M
authors.initials: HM
authors.lastname: Nguyen
mesh_terms: D002384:Catalysis; D006027:Glycosides / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D010165:Palladium / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D006027:Glycosides; D010165:Palladium