title: Is there an alternative to increasing the sample size in microarray studies?
abstract: Our answer to the question posed in the title is negative. This intentionally provocative note discusses the issue of sample size in microarray studies from several angles. We suggest that the current view of microarrays as no more than a screening tool be changed and small sample studies no longer be considered appropriate.
authors.affiliation: Department of Biostatistics and Computational Biology, University of Rochester, 601 Elmwood Avenue, Box 630, Rochester, New York 14642, USA.
authors.forename: Lev
authors.initials: L
authors.lastname: Klebanov
authors.forename: Andrei
authors.initials: A
authors.lastname: Yakovlev