title: Differences in lectin-binding properties between the common mucosal epithelium and follicle-associated epithelium in the rabbit small intestine.
abstract: Differences in sugar distribution between the villous epithelium and follicle-associated epithelium (FAE) were compared using lectins in the rabbit small intestine. In every portion, villous columnar epithelial cells primarily exhibited a positive reaction to the GalNAc, GlcNAc, galactose, and oligosaccharide. In the ileal Peyer's patch (PP), whereas microvillous epithelial cells exhibited positive reactions, M cells tended to be negative. The villous epithelial reaction to the fucose group was negative, but M cells and microvillous epithelial cells showed a positive to the fucose. No epithelium had a positive reaction to the mannose and glucose. The variety of lectin-binding properties of villous epithelial cells and M cells may reflect specificity for the recognizing luminal substances such as antigenic molecules and bacterial elements.
authors.affiliation: Department of Molecular Pathology, Ehime University School of Medicine, Toh-on, Ehime, Japan.
authors.forename: Takashi
authors.initials: T
authors.lastname: Takeuchi
authors.forename: Taketsugu
authors.initials: T
authors.lastname: Fujibuchi
authors.forename: Yoshinori
authors.initials: Y
authors.lastname: Imai
authors.forename: Yoshiaki
authors.initials: Y
authors.lastname: Kamei
authors.forename: Ryuichi
authors.initials: R
authors.lastname: Murase
authors.forename: Katsumi
authors.initials: K
authors.lastname: Kito
authors.forename: Yasuhito
authors.initials: Y
authors.lastname: Abe
authors.forename: Norifumi
authors.initials: N
authors.lastname: Ueda
mesh_terms: D000818:Animals; D015415:Biomarkers; D002241:Carbohydrates; D007413:Intestinal Mucosa / Q000166:cytology / Q000378:metabolism*; D007421:Intestine, Small / Q000033:anatomy & histology / Q000378:metabolism*; D037102:Lectins / Q000378:metabolism*; D008297:Male; D011485:Protein Binding; D011817:Rabbits
chemical_list: D015415:Biomarkers; D002241:Carbohydrates; D037102:Lectins