Evidence-based (S3) guidelines for the treatment of psoriasis vulgaris.
Psoriasis vulgaris is a common and often chronic inflammatory skin disease. The incidence of psoriasis in Western industrialized countries ranges from 1 to 2%. Patients afflicted with severe psoriasis vulgaris may experience a significant reduction in quality of life. Despite the large variety of treatment options available, patient surveys have revealed lack of satisfaction with the efficacy of available treatments and a high rate of non-compliance. To optimize the treatment of psoriasis in Germany, the Deutsche Dermatologische Gesellschaft (DDG) and the Berufsverband Deutscher Dermatologen (BVDD) initiated a project to develop evidence-based guidelines for the management of psoriasis. These resulting Guidelines focus on induction therapy in cases of mild, moderate, and severe plaquetype psoriasis in adults. The Guidelines include evidence-based evaluation of the efficacy of all currently available therapeutic options in Germany. In addition, they offer detailed information on how best to administer the various treatments and give information on contraindications, adverse drug reactions, and drug interactions as well as estimates of practicability and cost. The Guidelines were developed following the recommendations of the Arbeitsgemeinschaft wissenschaftlicher medizinischer Fachgesellschaften (AWMF). The therapeutic recommendations were developed by an expert group and finalized during interdisciplinary consensus conferences.
Nast
Alexander
A
Division of Evidence Based Medicine (dEBM), Klinik für Dermatologie, Venerologie und Allergologie, Charité-Universitätsmedizin Berlin, Germany.
Kopp
Ina B
IB
Augustin
Matthias
M
Banditt
Kirstin-Benita
KB
Boehncke
Wolf-Henning
WH
Follmann
Markus
M
Friedrich
Markus
M
Huber
Matthias
M
Kahl
Christina
C
Klaus
Joachim
J
Koza
Joachim
J
Kreiselmaier
Inga
I
Mohr
Johannes
J
Mrowietz
Ulrich
U
Ockenfels
Hans-Michael
HM
Orzechowski
Hans-Dieter
HD
Prinz
Jörg
J
Reich
Kristian
K
Rosenbach
Thomas
T
Rosumeck
Stefanie
S
Schlaeger
Martin
M
Schmid-Ott
Gerhard
G
Sebastian
Michael
M
Streit
Volker
V
Weberschock
Tobias
T
Rzany
Berthold
B
D003879:Dermatologic Agents / Q000592:standards* / Q000627:therapeutic use*; D003880:Dermatology / Q000592:standards*; D005858:Germany; D019983:Guideline Adherence; D006801:Humans; D010818:Practice Patterns, Physicians' / Q000592:standards*; D011565:Psoriasis / Q000188:drug therapy*
D003879:Dermatologic Agents