Intra-arterial thrombolysis in a 2-year-old with cardioembolic stroke.
Recombinant tissue plasminogen activator, although the standard of care for the management of acute ischemic stroke in adults, is used infrequently in children. The authors describe the use of intra-arterial recombinant tissue plasminogen activator in a young child with embolic stroke. Thrombolysis restored flow to the affected middle cerebral artery and appeared to limit the extent of the infarction and the severity of the subsequent neurologic deficits.
Benedict
Susan L
SL
Department of Pediatrics, University of Utah, Primary Children's Medical Center, Salt Lake City, Utah 84158, USA. susan.benedict@hsc.utah.edu
Ni
Oliver K
OK
Schloesser
Peter
P
White
Keith S
KS
Bale
James F
JF
D002675:Child, Preschool; D005260:Female; D005343:Fibrinolytic Agents / Q000627:therapeutic use*; D006801:Humans; D020244:Infarction, Middle Cerebral Artery; D007269:Injections, Intra-Arterial / Q000379:methods; D010960:Plasminogen Activators / Q000627:therapeutic use*; D020521:Stroke / Q000188:drug therapy*; D015912:Thrombolytic Therapy
D005343:Fibrinolytic Agents; D010960:Plasminogen Activators