title: Treatment of invasive cervical cancer: Rijeka experience.
abstract: The aim of this retrospective analysis was to evaluate the survival rate in 661 patients with cervical cancer regarding two time periods 1990-1996 and 1997-2003 and the specific stage related risk factors. The respective five-year survival was 71.7% and 80.0%. Analyzing the risk factors in the univariate and multivariate regression modalities ultimately only two parameters, the two time periods and FIGO staging were found to be independent prognostic factors. The observed total improvement in the survival rate of the second time period is followed by an increase in conservative surgery in stage TIA1, a reduction in the use of adjuvant radiotherapy among operable stages Tlbl, Tlb2 and T2A, while the treatment of locally advanced cervical cancer did not differ significantly.
authors.affiliation: Department of Obstetrics and Gynecology, Clinical Hospital Center Rijeka, University of Rijeka School of Medicine, Rijeka, Croatia. herman.haller@ri.t-com.hr
authors.forename: Herman
authors.initials: H
authors.lastname: Haller
authors.forename: Stanislav
authors.initials: S
authors.lastname: Rupcić
authors.forename: Maja
authors.initials: M
authors.lastname: Kratević
authors.forename: Ruzica
authors.initials: R
authors.lastname: Begonia
authors.forename: Miroslav
authors.initials: M
authors.lastname: Stamatović
authors.forename: Ozren
authors.initials: O
authors.lastname: Mamula
mesh_terms: D017523:Croatia; D005260:Female; D006801:Humans; D008499:Medical Records; D008875:Middle Aged; D016016:Proportional Hazards Models; D012189:Retrospective Studies; D016019:Survival Analysis; D002583:Uterine Cervical Neoplasms / Q000401:mortality* / Q000473:pathology / Q000601:surgery*