Adiponectin: starving for attention.
Maintaining energy balance involves the dynamic control of appetite and energy expenditure. A new study from the Kadowaki laboratory (Kubota et al., 2007) shows that the adipocyte-derived hormone adiponectin increases appetite and reduces energy expenditure by stimulating AMPK in the hypothalamus.
Steinberg
Gregory R
GR
St. Vincent's Institute, Department of Medicine, University of Melbourne, 41 Victoria Parade, Fitzroy, Victoria 3065, Australia. gsteinberg@svi.edu.au
Kemp
Bruce E
BE
D055372:AMP-Activated Protein Kinases; D052242:Adiponectin / Q000134:cerebrospinal fluid / Q000235:genetics / Q000502:physiology*; D000818:Animals; D004435:Eating; D004734:Energy Metabolism; D007031:Hypothalamus / Q000201:enzymology* / Q000473:pathology; D009097:Multienzyme Complexes / Q000235:genetics / Q000378:metabolism*; D017346:Protein Serine-Threonine Kinases / Q000235:genetics / Q000378:metabolism*
D052242:Adiponectin; D009097:Multienzyme Complexes; D017346:Protein Serine-Threonine Kinases; D055372:AMP-Activated Protein Kinases