Community-acquired methicillin-resistant Staphylococcus aureus causes severe disseminated infection and deep venous thrombosis in children: literature review and recommendations for management.
Community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) infection in children is increasingly common and can be associated with dissemination and life-threatening complications. Empiric therapy for presumed severe Staphylococcus aureus infection should be reviewed. Four children with severe invasive CA-MRSA infection causing osteomyelitis and pneumonia complicated by pulmonary embolus and deep venous thrombosis are described. The literature is reviewed and recommendations for management are provided.
Nourse
Clare
C
Mater Children's Hospital, Stanley Street, South Brisbane, QLD 4101, Australia. clare.nourse@mater.org.au
Starr
Mike
M
Munckhof
Wendy
W
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D017714:Community-Acquired Infections / Q000150:complications*; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D016106:Methicillin Resistance; D010019:Osteomyelitis / Q000000981:diagnostic imaging / Q000209:etiology* / Q000628:therapy; D011655:Pulmonary Embolism / Q000150:complications*; D013203:Staphylococcal Infections / Q000150:complications* / Q000188:drug therapy; D014463:Ultrasonography; D020246:Venous Thrombosis / Q000209:etiology* / Q000628:therapy