The coexistence of thymic carcinoma and multiple granulomas in a Turkish child.
Thymic carcinoma, which is a thymic epithelial neoplasm with obvious cytologic atypia, is a rare neoplasm. The authors report on a 10-year-old boy who presented with respiratory distress due to bulky anterior mediastinal mass. Histological and immunohistochemical studies confirmed a lymphoepithelioma-like pattern thymic carcinoma. In addition, evaluation of the specimen showed foci of caseation and multiple granulomas with extensive central necrosis within the thymic tissue. The child received chemotherapy, followed by surgery and radiotherapy. To rule out difficulties of tuberculosis he also received antituberculosis therapy. Two years after cessation of treatment, he is still in remission for thymic carcinoma.
Tacyildiz
Nurdan
N
Department of Pediatric Oncology, Ankara University Medical School, Ankara, Turkey. nurdantacyildiz@yahoo.com
Ugur
Handan
H
Yavuz
Gulsan
G
Unal
Emel
E
Comba
Atakan
A
Okten
Ilker
I
Ciftci
Ergin
E
Dogru
Ulker
U
Heper
Aylin Okcu
AO
Sak
Serpil Dizbay
SD
D002648:Child; D003131:Combined Modality Therapy; D006099:Granuloma / Q000150:complications* / Q000473:pathology / Q000628:therapy; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D012074:Remission Induction / Q000379:methods; D012131:Respiratory Insufficiency; D013945:Thymoma / Q000150:complications* / Q000473:pathology / Q000628:therapy; D014421:Turkey