New P,N-ferrocenyl ligands for the asymmetric Ir-catalyzed hydrogenation of imines.
The Ir-catalyzed enantioselective hydrogenation of various N-(3,5-dimethyl-4-methoxy)phenylimines was performed under mild conditions in the presence of new P,N-ferrocenyl iridium complexes leading to (R)-N-(3,5-dimethyl-4-methoxy)phenylamines in high yields and enantioselectivities (up to 99%). These chiral aryl amines can be readily deprotected using Ce(NH4)2(NO3)6.
Cheemala
Murthy N
MN
Department Chemie und Biochemie, Ludwig-Maximilians-Universität, Butenandtstrasse 5-13, 81377 München, Germany.
Knochel
Paul
P
D000588:Amines / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D005296:Ferrous Compounds / Q000737:chemistry*; D006865:Hydrogenation; D007097:Imines / Q000737:chemistry*; D007495:Iridium / Q000737:chemistry*; D008024:Ligands; D015394:Molecular Structure
D000588:Amines; D005296:Ferrous Compounds; D007097:Imines; D008024:Ligands; D007495:Iridium