title: Primary epithelioid sarcoma of the oesophagus.
abstract: Epithelioid sarcoma is a rare soft tissue tumour presenting two main variants: the 'classical' distal type and the more recently described proximal type. The latter is distinguished from the former by occurrence in elderly patients, more axial and deep location, prominent atypical and pleomorphic appearance and eventually aggressive clinical behaviour with poor outcome. To date, only few perivisceral epithelioid sarcomas have been described, and they are mainly related to the colon and bladder in pelvic and perineal sites. We report a hitherto undescribed epithelioid sarcoma of the distal oesophagus and discuss the relevance of molecular cytogenetics.
authors.affiliation: Medicina Sperimentale, Università La Sapienza Roma, Rome, Italy.
authors.forename: Francesca
authors.initials: F
authors.lastname: Maggiani
authors.forename: Maria
authors.initials: M
authors.lastname: Debiec-Rychter
authors.forename: Nadine
authors.initials: N
authors.lastname: Ectors
authors.forename: Antoon
authors.initials: A
authors.lastname: Lerut
authors.forename: Raf
authors.initials: R
authors.lastname: Sciot
mesh_terms: D020732:Cytogenetic Analysis; D004273:DNA, Neoplasm / Q000235:genetics; D004938:Esophageal Neoplasms / Q000175:diagnosis* / Q000235:genetics / Q000473:pathology; D004947:Esophagus / Q000378:metabolism / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D012509:Sarcoma / Q000175:diagnosis* / Q000235:genetics / Q000473:pathology; D051176:beta Catenin / Q000378:metabolism
chemical_list: D004273:DNA, Neoplasm; D051176:beta Catenin