Oncogenic osteomalacia.
A 59-year-old gentleman presented with symptoms of progressively worsening low back pain associated with difficulty in rising from a squat over a period of two years. Biochemical tests confirmed the initial clinical diagnosis of osteomalacia. Blood pool scanning revealed a focal hot spot on the site of the clinically visible swelling close to the metacarpo-phalangeal joint of the left index finger. The biopsy of the specimen obtained by excision was reported to be consistent with a phosphaturic mesenchymal tumour. The patient had complete resolution of symptoms six months following excision of the lesion.
Jacob
J J
JJ
Department of Endocrinology, Christian Medical College, Vellore, India.
Finny
P
P
Thomas
Meera
M
Thomas
N
N
John
M
M
D000469:Alkaline Phosphatase / Q000097:blood; D002118:Calcium / Q000097:blood; D006801:Humans; D017116:Low Back Pain / Q000209:etiology; D008297:Male; D008637:Mesenchymoma / Q000175:diagnosis*; D008662:Metacarpophalangeal Joint; D008875:Middle Aged; D010018:Osteomalacia / Q000209:etiology*; D010710:Phosphates / Q000097:blood; D012983:Soft Tissue Neoplasms / Q000175:diagnosis*
D010710:Phosphates; D000469:Alkaline Phosphatase; D002118:Calcium