title: Primary non-Hodgkin's lymphoma of the rectum.
abstract: BACKGROUND
  Primary rectal lymphoma is a very uncommon disease, therefore, it has received little attention in the literature. Because of their rarity, rectal lymphomas are generally included in the group of large intestine lymphomas.
  
  
  METHODS
  We report here a case of primary rectal B-cell lymphoma in a 67-year-old woman. The tumor was originally located in the rectum without evidence of any other lymphoma-involved organ. Histological findings revealed diffuse large B-cell lymphoma. The clinical stage was IE according to the Ann Arbor system. International prognostic index (IPI) was I (low-intermediate risk). We preferred a non-surgical, organ-sparing treatment which started with chemotherapy followed by radiation. 12 months after the end of therapy, there is no sign of tumor recurrence in our patient.
  
  
  CONCLUSIONS
  We suggest that histology-specific multidrug chemotherapy followed by radiotherapy seems to be a therapeutic approach that is appropriate fort this rare tumor.
authors.affiliation: Department of Medical Oncology, Institute of Oncology, Istanbul University, Turkey.
authors.forename: Nese
authors.initials: N
authors.lastname: Guney
authors.forename: Mert
authors.initials: M
authors.lastname: Basaran
authors.forename: Nihan
authors.initials: N
authors.lastname: Aksakalli
authors.forename: Sevil
authors.initials: S
authors.lastname: Bavbek
authors.forename: Gülçin
authors.initials: G
authors.lastname: Erseven
mesh_terms: D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001706:Biopsy; D003131:Combined Modality Therapy; D019583:Dose Fractionation, Radiation; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D016393:Lymphoma, B-Cell / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology / Q000532:radiotherapy; D016403:Lymphoma, Large B-Cell, Diffuse / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology / Q000532:radiotherapy; D009367:Neoplasm Staging; D018714:Radiotherapy, Adjuvant; D012004:Rectal Neoplasms / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology / Q000532:radiotherapy; D012007:Rectum / Q000473:pathology; D012812:Sigmoidoscopy