title: Indomethacin for recurrent cutaneous necrotizing eosinophilic vasculitis.
abstract: Recurrent cutaneous necrotizing eosinophilic vasculitis (RCNEV) is a rare disease characterized by clinical features of pruritic purpuric papules and angioedema. Skin biopsies revealed the eosinophil-predominate necrotizing vasculitis affecting small dermal vessels. Systemic corticosteroid is a very effective treatment. There are many side effects associated with systemic corticosteroid therapy. The authors report a case of RCNEVsuccessfully treated with indomethacin. To the authors'knowledge, there has been no reported case of RCNEV treated with indomethacin.
authors.affiliation: Skin Center, Bum- rungrad International Hospital, 33 Sukhumvit 3, Wattana, Bangkok 10110, Thailand. drchuchait@yahoo.com
authors.forename: Chuchai
authors.initials: C
authors.lastname: Tanglertsampan
authors.forename: Niyom
authors.initials: N
authors.lastname: Tantikun
authors.forename: Nopadon
authors.initials: N
authors.lastname: Noppakun
authors.forename: Virat
authors.initials: V
authors.lastname: Pinyopornpanit
mesh_terms: D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use*; D004802:Eosinophilia / Q000188:drug therapy / Q000473:pathology*; D004804:Eosinophils; D006801:Humans; D007213:Indomethacin / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D009336:Necrosis / Q000188:drug therapy* / Q000473:pathology; D012008:Recurrence; D017445:Skin Diseases, Vascular / Q000188:drug therapy* / Q000473:pathology; D014657:Vasculitis / Q000188:drug therapy* / Q000473:pathology
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D007213:Indomethacin