title: A dog with myelodysplastic syndrome: chronic myelomonocytic leukemia.
abstract: An eleven-year-old female pug was referred to Yamaguchi University Animal Hospital for evaluation of anemia and thrombocytopenia. The cytological examination of the peripheral blood showed some giant monocytic lineage blast cells. A few granulocytes and platelets had dysplastic features. On day 7, in addition to increasing the monocytic lineage cells, the dysplastic features of the blood had also increased compared to the initial examination. We performed bone marrow aspiration upon her death. The bone marrow revealed dysplastic features in all three hematopoietic cell lines, and an increase in the monocytic cell line. Based on the features of the bone marrow and the peripheral blood, this case was confirmed to be myelodysplastic syndrome--Chronic myelomonocytic leukaemia (MDS-CMML).
authors.affiliation: Laboratory of Veterinary Internal Medicine, Faculty of Agriculture, Yamaguchi University, Yoshida, Yamaguchi, Japan.
authors.forename: Hiroko
authors.initials: H
authors.lastname: Hiraoka
authors.forename: Masaharu
authors.initials: M
authors.lastname: Hisasue
authors.forename: Naho
authors.initials: N
authors.lastname: Nagashima
authors.forename: Takako
authors.initials: T
authors.lastname: Miyama
authors.forename: Takashi
authors.initials: T
authors.lastname: Tanimoto
authors.forename: Malaika
authors.initials: M
authors.lastname: Watanabe
authors.forename: Kazuhito
authors.initials: K
authors.lastname: Itamoto
authors.forename: Takuya
authors.initials: T
authors.lastname: Mizuno
authors.forename: Hisashi
authors.initials: H
authors.lastname: Inokuma
authors.forename: Masaru
authors.initials: M
authors.lastname: Okuda
mesh_terms: D000818:Animals; D016572:Cyclosporine / Q000627:therapeutic use; D004283:Dog Diseases / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D004285:Dogs; D005260:Female; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D015477:Leukemia, Myelomonocytic, Chronic / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology / Q000662:veterinary*
chemical_list: D007166:Immunosuppressive Agents; D016572:Cyclosporine