Multicentric reticulohistiocytosis with positive anticyclic citrullinated antibodies.
This is a case report of a woman with multicentric reticulohistiocytosis with positive anticyclic citrullinated antibodies. This patient had been misdiagnosed with rheumatoid arthritis for many years. Recently, she presented with symmetric distal interphalangeal joint destruction and papules along her nail beds. Her clinical presentation, laboratory data, radiographic and histologic findings were all consistent with multicentric reticulohistiocytosis, not rheumatoid arthritis. This is the first case report of a patient with multicentric reticulohistiocytosis that tested positive for anticyclic citrullinated antibodies.
Chauhan
Anupama
A
Division of Immunology/Rheumatology, William Davis Medical Research Center, The Ohio State University College of Medicine and Public Health, Columbus 43210-1228, USA. anupama.chauhan@osumc.edu
Mikulik
Zhanna
Z
Hackshaw
Kevin V
KV
D000368:Aged; D000974:Antibodies, Antinuclear / Q000097:blood*; D001172:Arthritis, Rheumatoid / Q000175:diagnosis; D015415:Biomarkers / Q000097:blood; D003951:Diagnostic Errors; D000068800:Etanercept; D005260:Female; D005384:Finger Joint / Q000473:pathology*; D015616:Histiocytosis, Non-Langerhans-Cell / Q000175:diagnosis* / Q000188:drug therapy / Q000276:immunology; D006801:Humans; D007074:Immunoglobulin G / Q000627:therapeutic use; D009262:Nails / Q000473:pathology; D010456:Peptides, Cyclic / Q000097:blood*; D018124:Receptors, Tumor Necrosis Factor / Q000627:therapeutic use
D000974:Antibodies, Antinuclear; D015415:Biomarkers; D007074:Immunoglobulin G; D010456:Peptides, Cyclic; D018124:Receptors, Tumor Necrosis Factor; C487763:cyclic citrullinated peptide; D000068800:Etanercept