title: [Transurethral resection of bladder tumors and prostate enlargement in physiological saline solution (TURIS). A prospective study].
abstract: BACKGROUND
  Transurethral resection in a conductive irrigant medium is a new procedure in the surgical therapy of bladder tumors and prostate enlargement. In this prospective randomized trial we compared conventional TUR with TUR in saline regarding safety and efficiency.
  
  
  METHODS
  Between November 2004 and February 2005 a total number of 128 patients were included in this study. After randomization 58 patients were treated by conventional TUR and 70 patients by TURIS (Olympus, SurgMasterSystem). We evaluated resection time, weight of resected tissue, complications, blood loss, changes in serum sodium, and duration of catheterization.
  
  
  RESULTS
  Among the tested procedures no statistically significant difference could be observed concerning blood loss, change of serum sodium, and complications. The mean weight of resected tissue of the prostate per time was 0.9 g/min with the TUR procedure and 0.8 g/min with the TURIS procedure. Severe complications like TUR syndrome or perforation of the bladder were not observed at all. In the TURIS group time until catheter removal was longer but also the mean weight of resected tissue of the prostate was higher in the TURIS group (42 g) than in the conventional TUR group (31 g).
  
  
  CONCLUSIONS
  Transurethral resection in a conductive irrigant medium (TURIS) can be considered as a safe and effective surgical procedure in the treatment of BPH and superficial urothelial carcinoma. Moreover the risk of TUR syndrome and perforation of the bladder due to nerve stimulation is reduced.
authors.affiliation: Urologische Klinik, Universitätsklinikum, Hufelandstrasse 55, 45122 Essen. roseachim@web.de
authors.forename: A
authors.initials: A
authors.lastname: Rose
authors.forename: S
authors.initials: S
authors.lastname: Suttor
authors.forename: P J
authors.initials: PJ
authors.lastname: Goebell
authors.forename: R
authors.initials: R
authors.lastname: Rossi
authors.forename: H
authors.initials: H
authors.lastname: Rübben
mesh_terms: D016063:Blood Loss, Surgical; D002295:Carcinoma, Transitional Cell / Q000473:pathology / Q000601:surgery*; D020684:Cystoscopes; D004598:Electrosurgery / Q000295:instrumentation*; D005260:Female; D006417:Hematuria / Q000209:etiology; D006801:Humans; D008297:Male; D011183:Postoperative Complications / Q000209:etiology; D011446:Prospective Studies; D011470:Prostatic Hyperplasia / Q000473:pathology / Q000601:surgery*; D012965:Sodium Chloride; D007507:Therapeutic Irrigation / Q000295:instrumentation*; D020728:Transurethral Resection of Prostate / Q000295:instrumentation*; D001749:Urinary Bladder Neoplasms / Q000473:pathology / Q000601:surgery*
chemical_list: D012965:Sodium Chloride