title: Life threatening hemorrhage from osteoradionecrosis of the ribs and clavicle.
abstract: Osteoradionecrosis (ORN) is a familiar complication of radiotherapy. ORN of the clavicle and ribs is well documented after radiation therapy for breast and pulmonary malignancy. ORN of the clavicle after radiation therapy to the neck is very rare. We report the first case in which both clavicles and first ribs underwent ORN 14 years after neck irradiation and surgery for laryngeal malignancy. The presentation was atypical; erosion of the right internal mammary artery causing life-threatening hemorrhage. Otolaryngologists should be aware that ORN can occur at an unusual site and can have an atypical presentation.
authors.affiliation: Department of Otolaryngology, Royal Alexandra Hospital, Paisley, United Kingdom. iqbalms@hotmail.com
authors.forename: Mohammed Iqbal
authors.initials: MI
authors.lastname: Syed
authors.forename: Louise J
authors.initials: LJ
authors.lastname: Clark
authors.forename: Calum
authors.initials: C
authors.lastname: Adams
mesh_terms: D000368:Aged; D001847:Bone Diseases / Q000150:complications* / Q000000981:diagnostic imaging; D002968:Clavicle; D006470:Hemorrhage / Q000175:diagnosis / Q000209:etiology*; D006801:Humans; D007822:Laryngeal Neoplasms / Q000532:radiotherapy* / Q000601:surgery; D008297:Male; D008323:Mammary Arteries / Q000293:injuries*; D010025:Osteoradionecrosis / Q000150:complications* / Q000000981:diagnostic imaging; D012272:Ribs; D013997:Time Factors; D014057:Tomography, X-Ray Computed