Tuberculosis infection control in resource-limited settings in the era of expanding HIV care and treatment.
The opportunities for human immunodeficiency virus (HIV) care and treatment created by new treatment initiatives promoting universal access are also creating unprecedented opportunities for persons with HIV-associated immunosuppression to be exposed to patients with infectious tuberculosis (TB) within health care facilities, with the attendant risks of acquiring TB infection and developing TB disease. Infection control measures can reduce the risk of Mycobacterium tuberculosis transmission even in settings with limited resources, on the basis of a 3-level hierarchy of controls, including administrative or work practice, environmental controls, and respiratory protection. Further research is needed to define the most efficient interventions. The importance of preventing transmission of M. tuberculosis in the era of expanding HIV care and treatment in resource-limited settings must be recognized and addressed.
Bock
Naomi N
NN
Global AIDS Program, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA. neb2@cdc.gov
Jensen
Paul A
PA
Miller
Bess
B
Nardell
Edward
E
D003428:Cross Infection / Q000517:prevention & control; D003906:Developing Countries; D018562:Disease Transmission, Infectious / Q000517:prevention & control; D015658:HIV Infections / Q000150:complications / Q000188:drug therapy* / Q000517:prevention & control*; D006801:Humans; D017053:Infection Control; D009169:Mycobacterium tuberculosis; D014376:Tuberculosis / Q000175:diagnosis / Q000517:prevention & control* / Q000635:transmission