title: The coexistence of thymic carcinoma and multiple granulomas in a Turkish child.
abstract: Thymic carcinoma, which is a thymic epithelial neoplasm with obvious cytologic atypia, is a rare neoplasm. The authors report on a 10-year-old boy who presented with respiratory distress due to bulky anterior mediastinal mass. Histological and immunohistochemical studies confirmed a lymphoepithelioma-like pattern thymic carcinoma. In addition, evaluation of the specimen showed foci of caseation and multiple granulomas with extensive central necrosis within the thymic tissue. The child received chemotherapy, followed by surgery and radiotherapy. To rule out difficulties of tuberculosis he also received antituberculosis therapy. Two years after cessation of treatment, he is still in remission for thymic carcinoma.
authors.affiliation: Department of Pediatric Oncology, Ankara University Medical School, Ankara, Turkey. nurdantacyildiz@yahoo.com
authors.forename: Nurdan
authors.initials: N
authors.lastname: Tacyildiz
authors.forename: Handan
authors.initials: H
authors.lastname: Ugur
authors.forename: Gulsan
authors.initials: G
authors.lastname: Yavuz
authors.forename: Emel
authors.initials: E
authors.lastname: Unal
authors.forename: Atakan
authors.initials: A
authors.lastname: Comba
authors.forename: Ilker
authors.initials: I
authors.lastname: Okten
authors.forename: Ergin
authors.initials: E
authors.lastname: Ciftci
authors.forename: Ulker
authors.initials: U
authors.lastname: Dogru
authors.forename: Aylin Okcu
authors.initials: AO
authors.lastname: Heper
authors.forename: Serpil Dizbay
authors.initials: SD
authors.lastname: Sak
mesh_terms: D002648:Child; D003131:Combined Modality Therapy; D006099:Granuloma / Q000150:complications* / Q000473:pathology / Q000628:therapy; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D012074:Remission Induction / Q000379:methods; D012131:Respiratory Insufficiency; D013945:Thymoma / Q000150:complications* / Q000473:pathology / Q000628:therapy; D014421:Turkey