title: Abyssomicins G and H and atrop-abyssomicin C from the marine Verrucosispora strain AB-18-032.
abstract: Abyssomicin C is a complex polyketide-type antibiotic and the first natural inhibitor of the p-aminobenzoate biosynthesis produced by the marine Verrucosispora strain AB-18-032. We have now isolated three novel naturally produced abyssomicins, among them the even more active atrop-abyssomicin C. The chemical structures were elucidated by mass spectrometry and NMR spectroscopy.
authors.affiliation: Institut für Chemie, FG Organische Chemie, Technische Universität Berlin, Germany.
authors.forename: Simone
authors.initials: S
authors.lastname: Keller
authors.forename: Graeme
authors.initials: G
authors.lastname: Nicholson
authors.forename: Carmen
authors.initials: C
authors.lastname: Drahl
authors.forename: Erik
authors.initials: E
authors.lastname: Sorensen
authors.forename: Hans-Peter
authors.initials: HP
authors.lastname: Fiedler
authors.forename: Roderich D
authors.initials: RD
authors.lastname: Süssmuth
mesh_terms: D039903:Actinobacteria / Q000737:chemistry*; D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000302:isolation & purification*; D019086:Bridged Bicyclo Compounds, Heterocyclic / Q000737:chemistry / Q000302:isolation & purification*; D018942:Macrolides / Q000737:chemistry / Q000302:isolation & purification*; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D021241:Spectrometry, Mass, Electrospray Ionization
chemical_list: D000900:Anti-Bacterial Agents; D019086:Bridged Bicyclo Compounds, Heterocyclic; D018942:Macrolides