title: Experimental study on vasoactive intestinal peptide (VIP) and its diaminopropane bound (VIP-DAP) analog in solution.
abstract: Bioactive peptides represent an exciting area of research in the fields of biochemistry and medicine and in particular the VIP/PACAP network appears to be of interest. Vasoactive intestinal peptide (VIP) is a pleiotropic factor that exerts a physiological regulatory influence and is involved in the pathogenesis of several human disorders. In this paper we have reported structural characterization of VIP by experimental and computational methods as well as a comparative analysis of the peptide with its transglutaminase catalyzed analog VIP-Diaminopropane (VIP-DAP).
authors.affiliation: Dipartimento di Oncologia Sperimentale, Istituto Nazionale Tumori Fondazione G. Pascale, Naples, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Caraglia
authors.forename: M
authors.initials: M
authors.lastname: Carteni
authors.forename: A
authors.initials: A
authors.lastname: Dicitore
authors.forename: D
authors.initials: D
authors.lastname: Cassese
authors.forename: S
authors.initials: S
authors.lastname: De Maria
authors.forename: P
authors.initials: P
authors.lastname: Ferranti
authors.forename: G
authors.initials: G
authors.lastname: Giuberti
authors.forename: A
authors.initials: A
authors.lastname: Abbruzzese
authors.forename: P
authors.initials: P
authors.lastname: Stiuso
mesh_terms: D000818:Animals; D003959:Diamines / Q000737:chemistry*; D006801:Humans; D008958:Models, Molecular; D012996:Solutions / Q000737:chemistry; D013997:Time Factors; D014660:Vasoactive Intestinal Peptide / Q000737:chemistry*
chemical_list: D003959:Diamines; D012996:Solutions; D014660:Vasoactive Intestinal Peptide; C009475:trimethylenediamine