Predictors of influenza vaccination in HIV-infected patients in the United States, 1990-2002.
BACKGROUND
Although annual influenza vaccination of human immunodeficiency virus (HIV)-infected patients has been recommended in the United States since the early 1990s, vaccine coverage in this population is reported to be low. The objectives of the present study were to assess trends in influenza vaccination coverage in HIV-infected patients and to determine predictors of influenza vaccination.


METHODS
We analyzed data from the medical records of 51,021 HIV-infected patients from 10 US cities observed in a longitudinal cohort study between 1990 and 2002. Using multivariate logistic regression, we determined predictors of influenza vaccination for both the pre-highly active antiretroviral therapy (HAART) and HAART eras.


RESULTS
Vaccination coverage increased from 28.5% in the 1990 to 41.6% in the 2002 influenza season. Vaccine coverage increased with increasing age and frequency of medical visits. In the HAART era, persons prescribed antiretroviral therapy were more likely and those with higher viral loads and lower CD4 T cell counts were less likely to have received influenza vaccine.


CONCLUSIONS
Although influenza vaccination coverage in this population has increased in recent years, it is well below the Healthy People 2010 target of 60%. Efforts should be undertaken to increase influenza vaccination in HIV-infected persons.
Gallagher
Kathleen M
KM
Division of HIV/AIDS Prevention, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA. kxg7@cdc.gov
Juhasz
Marta
M
Harris
Norma S
NS
Teshale
Eyasu H
EH
D000293:Adolescent; D000328:Adult; D023241:Antiretroviral Therapy, Highly Active; D005260:Female; D015658:HIV Infections / Q000150:complications* / Q000453:epidemiology / Q000276:immunology*; D006801:Humans; D007252:Influenza Vaccines / Q000008:administration & dosage* / Q000276:immunology*; D007251:Influenza, Human / Q000150:complications* / Q000276:immunology / Q000517:prevention & control*; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D013997:Time Factors; D014481:United States / Q000453:epidemiology
D007252:Influenza Vaccines