Allelic diversity in KIR2DL4 in a bone marrow transplant population: description of three novel alleles.
Genomic DNA sequencing was used to identify alleles of KIR2DL4 from 78 unrelated individuals involved in hematopoietic stem cell transplants. Eight known alleles were observed. Three new alleles, KIR2DL4*00203, *00502, *0080104, which differ from known alleles at the nucleotide but not at the protein sequence level, were also identified.
Shulse
C
C
Department of Oncology, CW Bill Young Marrow Donor Recruitment and Research Program, Georgetown University Medical Center, Washington, DC 20057, USA.
Steiner
N K
NK
Hurley
C K
CK
D000483:Alleles; D016026:Bone Marrow Transplantation / Q000276:immunology*; D014644:Genetic Variation; D006801:Humans; D011971:Receptors, Immunologic / Q000235:genetics*; D054340:Receptors, KIR; D054345:Receptors, KIR2DL4
C515079:KIR2DL4 protein, human; D011971:Receptors, Immunologic; D054340:Receptors, KIR; D054345:Receptors, KIR2DL4