title: Prevalence of cocaine use in ED patients with severe hypertension.
abstract: OBJECTIVE
  We prospectively evaluated the prevalence of cocaine use in emergency department patients with elevated diastolic blood pressure greater than 120 mm Hg.
  
  
  METHODS
  Urine was collected on adult patients with diastolic blood pressure greater than 120 mm Hg. The Institutional Review Board granted a waiver of informed consent based on complete deidentification of the data to prevent selection bias. Spontaneously voided urine specimens were analyzed for the presence of the benzoylecgonine.
  
  
  RESULTS
  Of 107 eligible patients with a diastolic blood pressure equal to or greater than 120 mm Hg, 99 were tested. Of the 99, 13 (13%) tested positive, and of which, 6 (46%) presented with a request for medication refill. Five patients (39%) had cardiovascular and/or pulmonary complaints.
  
  
  CONCLUSIONS
  Emergency department patients with hypertension who have recently used cocaine may be difficult to differentiate from those who have not. Consideration should be given to the potential for cocaine use when making treatment decisions in patients with hypertension.
authors.affiliation: bUniversity of Texas Southwestern Medical Center, Dallas, TX 75235, USA. melissa.givens@us.army.mil
authors.forename: Melissa L
authors.initials: ML
authors.lastname: Givens
authors.forename: Rebecca
authors.initials: R
authors.lastname: Wald
authors.forename: Jason
authors.initials: J
authors.lastname: Schafer
authors.forename: Frank
authors.initials: F
authors.lastname: Wians
authors.forename: Kathleen
authors.initials: K
authors.lastname: Delaney
mesh_terms: D000328:Adult; D003042:Cocaine / Q000031:analogs & derivatives / Q000506:poisoning / Q000652:urine; D019970:Cocaine-Related Disorders / Q000453:epidemiology*; D004636:Emergency Service, Hospital; D006784:Hospitals, Teaching; D006786:Hospitals, Urban; D006801:Humans; D006973:Hypertension; D019370:Observation; D015995:Prevalence; D011446:Prospective Studies; D016037:Single-Blind Method
chemical_list: C005618:benzoylecgonine; D003042:Cocaine