title: Distribution of Streptococcus pneumoniae serotypes in nasopharyngeal carriage and in invasive pneumococcal disease in Sao Paulo, Brazil.
abstract: To determine whether serotypes of S. pneumoniae isolated from the nasopharynx (NP) are representative of data from patients with invasive disease, we collected NP swab specimens from children, between 3 months and 5 years and obtained data from 105 children hospitalized with invasive disease. The prevalence of penicillin nonsusceptible strains in the NP carriage and invasive disease group was 16.4% and 17%, respectively, in the first period and 42% and 45% in the second period. The serotypes 23F, 6A, 14 and 19F were the most common in the NP study and 14, 1, 5 and 6B were the most common in invasive infections.
authors.affiliation: Santa Casa S. Paulo University Hospital--Pediatrics Infectious Diseases Unit, S. Paulo, Brazil. eberezin2003@yahoo.com
authors.forename: Eitan N
authors.initials: EN
authors.lastname: Berezin
authors.forename: Maria D
authors.initials: MD
authors.lastname: Cardenuto
authors.forename: Leda L
authors.initials: LL
authors.lastname: Ferreira
authors.forename: Marcelo
authors.initials: M
authors.lastname: Otsuka
authors.forename: Maria L
authors.initials: ML
authors.lastname: Guerra
authors.forename: Maria Cristina C
authors.initials: MC
authors.lastname: Brandileone
mesh_terms: D001938:Brazil / Q000453:epidemiology; D002353:Carrier State / Q000453:epidemiology / Q000382:microbiology*; D002675:Child, Preschool; D006801:Humans; D007223:Infant; D009305:Nasopharynx / Q000382:microbiology*; D011008:Pneumococcal Infections / Q000453:epidemiology* / Q000382:microbiology*; D013296:Streptococcus pneumoniae / Q000145:classification* / Q000302:isolation & purification