Effectiveness of activated hydrogen ions in neutralizing paraquat intoxication in rats.
OBJECTIVE
Investigate the effectiveness of H4O in preventing the paraquat's effect in rats.


METHODS
Disease-free male spraque Dawley rats were used in the experiment. They were divided into two groups of 5, as the control group and the experiment group. All rats were poisoned with paraquat. The control group was fed water (H2O) while the experiment group was fed activated hydrogen ions (H4O).


RESULTS
The mortality of rats was equal (40%) in both groups. The control group died earlier than the experimental group (48 hours, 96 hours). In the rats that could survive till 1 month, the pathology of the lungs in the experimental group revealed less severity than the control group.


CONCLUSIONS
This may reflect the protective effects of activated hydrogen ions in the lungs, which are abundant in oxygen, and may offer fruitful results in humans.
Saenghirunvattana
Sawang
S
Samitivej Hospital, Bangkok, Thailand.
Laohathai
Piboon
P
Sangguanrungsirikul
Sompol
S
Worapongpaiboon
Surapon
S
Masakul
Narumol
N
Saenghirunvattana
Kasem
K
D000818:Animals; D006470:Hemorrhage / Q000628:therapy*; D008099:Liver / Q000187:drug effects; D008168:Lung / Q000187:drug effects; D017563:Lung Diseases, Interstitial / Q000628:therapy*; D008297:Male; D010269:Paraquat / Q000506:poisoning / Q000633:toxicity*; D061766:Proton Therapy; D051381:Rats; D017207:Rats, Sprague-Dawley
D010269:Paraquat