New 14-hydroxy-taxane and 2alpha,20-epoxy-11(15-->1)abeotaxane from the needles of Taxus canadensis.
Two new taxanes were isolated from the needles of Taxus canadensis. Their structures were established as 10beta,13alpha-diacetoxytaxa-4(20),11-diene-5alpha,9alpha,14beta-triol (1) and 4alpha,13alpha-diacetoxy-2alpha,20-epoxy-11(15-->1)abeotaxa-11,15-diene-5alpha,7beta,9alpha,10beta-tetraol (2) on the basis of a spectroscopic analysis.
Shi
Qing-Wen
QW
Department of Medicinal Natural Product Chemistry, School of Pharmaceutical Sciences, Hebei Medical University, Shijiazhuang, PR China. shiqingwen@hebmu.edu.cn
Dong
Mei
M
Huo
Chang-Hong
CH
Su
Xiao-Hui
XH
Li
Cun-Fang
CF
Zhang
Xi-Ping
XP
Wang
Yu-Fang
YF
Kiyota
Hiromasa
H
D004224:Diterpenes / Q000737:chemistry / Q000302:isolation & purification; D004852:Epoxy Compounds / Q000737:chemistry* / Q000302:isolation & purification; D018515:Plant Leaves / Q000737:chemistry; D043823:Taxoids / Q000737:chemistry* / Q000302:isolation & purification; D020946:Taxus / Q000737:chemistry*
D004224:Diterpenes; D004852:Epoxy Compounds; D043823:Taxoids