title: Effect of adding exercise to a diet containing glucomannan.
abstract: The aim of this study was to examine the effect of adding a total-body exercise program to an 8-week diet supplemented with glucomannan on weight loss, body composition, blood parameters, and physical performance in overweight men and women. Sedentary men and women who were overweight (body mass index>25 kg m(-2)) (men: 18-57 years, 27.0+/-11.2 years, 177.5+/-7.6 cm, 102.4+/-14.9 kg; women: 18-52 years, 33.4+/-12.1 years, 160.6+/-4.6 cm, 79.9+/-9.3 kg) completed an 8-week diet with 3000 mg glucomannan combined with either no exercise (No-Ex) (10 men, 10 women) or a resistance and endurance exercise training program (Ex) (12 men, 10 women). The diet emphasized healthy food choices and portion size control. The exercise training consisted of 3 weekly sessions of approximately 1 hour of a nonlinear periodized total-body resistance exercise program followed by 30 minutes of endurance exercise. After the intervention, there were reductions (P<.05) in body mass (men, -2.7+/-1.4 and -3.0+/-4.0 kg; women, -2.2+/-1.5 and -3.3+/-1.5 kg; No-Ex and Ex, respectively), fat mass (men, -2.3+/-1.6 and -3.9+/-2.5 kg; women, -2.6+/-1.4 and -3.6+/-1.1 kg; No-Ex and Ex, respectively), total cholesterol (TC) (men, -17.9+/-21.5 and -18.8+/-19.4 mg dL(-1); women, -9.3+/-20.0 and -10.1+/-19.5 mg dL(-1); No-Ex and Ex, respectively), and low-density lipoprotein cholesterol. Exercise significantly improved high-density lipoprotein cholesterol (HDL-C) (No-Ex, -2.0+/-4.7 and -2.3+/-4.5 mg dL(-1) vs Ex, 4.4+/-10.8 and 1.6+/-3.6 mg dL(-1); men and women, respectively), TC/HDL-C ratio, squat and bench press 1-repetition maximum, and distance covered during a shuttle-run test. In addition, exercise appeared to augment the reduction in fat mass (by 63% and 50%; men and women, respectively) and waist circumference, but did not affect total weight loss. Addition of a resistance and endurance exercise training program to a glucomannan diet regimen significantly improved measures of body composition, HDL-C, and TC/HDL-C ratio.
authors.affiliation: Department of Kinesiology, Human Performance Laboratory, University of Connecticut, Storrs, CT 06269, USA. william.kraemer@uconn.edu
authors.forename: William J
authors.initials: WJ
authors.lastname: Kraemer
authors.forename: Jakob L
authors.initials: JL
authors.lastname: Vingren
authors.forename: Ricardo
authors.initials: R
authors.lastname: Silvestre
authors.forename: Barry A
authors.initials: BA
authors.lastname: Spiering
authors.forename: Disa L
authors.initials: DL
authors.lastname: Hatfield
authors.forename: Jen Y
authors.initials: JY
authors.lastname: Ho
authors.forename: Maren S
authors.initials: MS
authors.lastname: Fragala
authors.forename: Carl M
authors.initials: CM
authors.lastname: Maresh
authors.forename: Jeff S
authors.initials: JS
authors.lastname: Volek
mesh_terms: D000293:Adolescent; D000328:Adult; D000886:Anthropometry; D001786:Blood Glucose / Q000378:metabolism; D001823:Body Composition / Q000187:drug effects / Q000502:physiology; D015992:Body Mass Index; D004032:Diet; D004797:Enzyme-Linked Immunosorbent Assay; D015444:Exercise / Q000502:physiology*; D005080:Exercise Test; D005260:Female; D006801:Humans; D007328:Insulin / Q000097:blood; D008055:Lipids / Q000097:blood; D008297:Male; D008351:Mannans / Q000494:pharmacology*; D008875:Middle Aged; D010807:Physical Endurance / Q000502:physiology; D010809:Physical Fitness / Q000502:physiology*; D012727:Sex Characteristics; D014891:Weight Lifting / Q000502:physiology; D015431:Weight Loss / Q000187:drug effects*
chemical_list: D001786:Blood Glucose; D007328:Insulin; D008055:Lipids; D008351:Mannans; C022901:(1-6)-alpha-glucomannan