Integrating actin assembly and endocytosis.
The extent to which the many different pathways of endocytosis share underlying molecular mechanisms is currently unknown. In this issue of Developmental Cell, Yarar et al. (2007) report that SNX9, a protein that binds phosphatidylinositides, dynamin, and N-WASP, coordinates actin assembly with several distinct endocytic processes.
Roth
Michael G
MG
Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA. michael.roth@utsouthwestern.edu
D000199:Actins / Q000378:metabolism*; D000818:Animals; D004705:Endocytosis / Q000502:physiology*; D008840:Microfilament Proteins / Q000378:metabolism*
D000199:Actins; D008840:Microfilament Proteins