title: Chemo- and stereoselective reaction between alkyl isocyanides and dimethyl 1,3-acetonedicarbocxylate in the presence of acetylenic esters.
abstract: The reaction of alkyl isocyanides with dimethyl 1,3-acetonedicarboxylate in the presence of dialkyl acetylenedicarboxylates in CH(2)Cl(2) at ambient temperature leads to highly functionalized 2-amino-4H-pyrans and 1,2-dialkyl 4,6-dimethyl-(1E, 3E)-3 (alkylamino)-5-oxo-1,3-hexadiene-1,2,4,6-tetracarboxylates.
authors.affiliation: Department of Chemistry, Faculty of Science, University of Kurdistan, P.O. Box 416, Sanandaj, Iran. FNasiri@uok.ac.ir
authors.forename: Farogh
authors.initials: F
authors.lastname: Nasiri
authors.forename: Fatemeh
authors.initials: F
authors.lastname: Nazem
authors.forename: Kourosh
authors.initials: K
authors.lastname: Pourdavaie
mesh_terms: D000480:Alkynes / Q000737:chemistry / Q000378:metabolism*; D004952:Esters / Q000737:chemistry / Q000378:metabolism; D007656:Ketoglutaric Acids / Q000737:chemistry / Q000378:metabolism*; D008954:Models, Biological; D008968:Molecular Conformation; D009570:Nitriles / Q000737:chemistry / Q000378:metabolism*; D013329:Structure-Activity Relationship; D013379:Substrate Specificity
chemical_list: D000480:Alkynes; D004952:Esters; D007656:Ketoglutaric Acids; D009570:Nitriles; C524329:dimethyl 1,3-acetonedicarboxylate