Novel polymer-supported chiral catalysts for the asymmetric addition of diethylzinc to aldehydes.
Newly synthesized polymer-supported chiral amino alcohol catalysts 5a and 5b have been proved to be effective for the enantioselective addition of diethylzinc to aldehydes, affording the corresponding sec-alcohols in moderate enantiomeric excesses with good to excellent yields. The recycled catalyst could be reused in the same reaction without significant deterioration in performance.
Wang
Su-Xi
SX
Department of Chemistry, Fudan University, Shanghai, People's Republic of China.
Chen
Fen-Er
FE
D000447:Aldehydes / Q000737:chemistry*; D002384:Catalysis; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D011108:Polymers / Q000737:chemistry*; D013237:Stereoisomerism
D000447:Aldehydes; D009942:Organometallic Compounds; D011108:Polymers; C454811:diethylzinc