Unusual abdominal findings of all-trans-retinoic acid syndrome: role of diagnostic imaging.
The standard therapy for patients affected by acute promyelocytic leukemia is based on all-trans-retinoic acid (ATRA), whose rare complication is a syndrome known as retinoic acid syndrome. We describe for the first time the computed tomography findings of a case of ATRA syndrome with typical pulmonary findings, along with the involvement of the upper abdomen organs (liver and spleen) as a further complication of the pathology.
La Fianza
Alfredo
A
Istituto di Radiologia, Università di Pavia, Fondazione IRCCS Policlinico S. Matteo, Pavia, Italy. a.lafianza@smatteo.pv.it
Bonfichi
Maurizio
M
Gorone
Maria Sole Prevedoni
MS
Gallotti
Anna
A
Torretta
Lorella
L
D000005:Abdomen / Q000000981:diagnostic imaging* / Q000473:pathology*; D000208:Acute Disease; D000328:Adult; D017809:Fatal Outcome; D006801:Humans; D015473:Leukemia, Promyelocytic, Acute / Q000150:complications* / Q000188:drug therapy*; D008297:Male; D013577:Syndrome; D014212:Tretinoin / Q000009:adverse effects* / Q000627:therapeutic use*; D014463:Ultrasonography
D014212:Tretinoin