title: Field evaluation of a rota- and adenovirus immunochromatographic assay using stool samples from children with acute diarrhea in Ghana.
abstract: We evaluated the Rida Quick rotavirus/adenovirus Combi rapid immunochromatographic test (ICT) under field conditions with Ghanaian children with acute diarrhea. Compared to PCR results, sensitivities and specificities were 75% and 95% for rotavirus and 22% and 84% for adenovirus. In resource-poor settings, ICTs may help to overcome difficulties in the diagnosis of rotavirus infection.
authors.affiliation: Institute of Tropical Medicine and International Health, Charité, University Medicine Berlin, Spandauer Damm 130, D-14050 Berlin, Germany. thomas.weitzel@charite.de
authors.forename: Thomas
authors.initials: T
authors.lastname: Weitzel
authors.forename: Klaus
authors.initials: K
authors.lastname: Reither
authors.forename: Frank P
authors.initials: FP
authors.lastname: Mockenhaupt
authors.forename: Klaus
authors.initials: K
authors.lastname: Stark
authors.forename: Ralf
authors.initials: R
authors.lastname: Ignatius
authors.forename: Eiman
authors.initials: E
authors.lastname: Saad
authors.forename: Andrew
authors.initials: A
authors.lastname: Seidu-Korkor
authors.forename: Ulrich
authors.initials: U
authors.lastname: Bienzle
authors.forename: Eckart
authors.initials: E
authors.lastname: Schreier
mesh_terms: D000256:Adenoviridae / Q000302:isolation & purification*; D000257:Adenoviridae Infections / Q000175:diagnosis / Q000821:virology*; D002648:Child; D002675:Child, Preschool; D002846:Chromatography, Affinity / Q000379:methods*; D003967:Diarrhea / Q000821:virology; D005869:Ghana; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D016133:Polymerase Chain Reaction; D012401:Rotavirus / Q000302:isolation & purification*; D012400:Rotavirus Infections / Q000175:diagnosis / Q000821:virology*; D012680:Sensitivity and Specificity; D014773:Virology / Q000379:methods*