title: Inhibitory activity against tobacco mosaic virus (TMV) replication of pinoresinol and syringaresinol lignans and their glycosides from the root of Rhus javanica var. roxburghiana.
abstract: Four new diepoxylignan glycosides, pinoresinol-4'-O-[6' '-O-(E)-feruloyl]-beta-D-glucopyranoside (1), pinoresinol-4'-O-[4' ',6' '-O-(E)-diferuloyl]-beta-D-glucopyranoside (2), pinoresinol-4'-O-[3' ',6' '-O-(E)-diferuloyl]-beta-D-glucopyranoside (3), and syringaresinol- 4'-O-[4' ',6' '-O-(E)-diferuloyl]-beta-D-glucopyranoside (4), together with three known compounds, pinoresinol (5), syringaresinol (6), and pinoresinol-4'-O-beta-D-glucopyranoside (7), were isolated from the n-butanol extract of Rhus javanica var. roxburghiana, and their structures were established using various spectroscopic techniques. Three glycosides (2-4) of the lignans showed moderate inhibition of multiplication of the tobacco mosaic virus.
authors.affiliation: Department of Chemistry, National Taiwan University, Taipei 106, Taiwan.
authors.forename: Ming-An
authors.initials: MA
authors.lastname: Ouyang
authors.forename: Yung-Shung
authors.initials: YS
authors.lastname: Wein
authors.forename: Zhen-Kun
authors.initials: ZK
authors.lastname: Zhang
authors.forename: Yueh-Hsiung
authors.initials: YH
authors.lastname: Kuo
mesh_terms: D005663:Furans / Q000494:pharmacology*; D006027:Glycosides / Q000494:pharmacology; D017705:Lignans / Q000494:pharmacology*; D018517:Plant Roots / Q000737:chemistry*; D029045:Rhus / Q000737:chemistry*; D014027:Tobacco Mosaic Virus / Q000187:drug effects*; D014779:Virus Replication / Q000187:drug effects*
chemical_list: D005663:Furans; D006027:Glycosides; D017705:Lignans; C042192:syringaresinol; C103298:pinoresinol