title: Three new triterpenoid saponins from the rhizomes of Impatiens pritzellii var. hupehensis.
abstract: Three new triterpenoid saponins, impatiprins A-C (1-3), together with a known triterpenoid (4) and two known triterpenoid saponins (5, 6), were isolated from the rhizomes of Impatiens pritzellii Hook. f. var. hupehensis Hook. f. The structures of 1-3 were determined by 1D and 2D NMR, FAB-MS techniques and chemical methods. Compounds 1 and 2 showed weak cytotoxicities against S-180, HeLa and HepG2 cell lines.
authors.affiliation: Faculty of Pharmaceutical Sciences, Tongji Medical College of Huazhong University of Science and Technology, Wuhan 430030, China.
authors.forename: X-F
authors.initials: XF
authors.lastname: Zhou
authors.forename: X-Y
authors.initials: XY
authors.lastname: Zhao
authors.forename: L
authors.initials: L
authors.lastname: Tang
authors.forename: H-L
authors.initials: HL
authors.lastname: Ruan
authors.forename: Y-H
authors.initials: YH
authors.lastname: Zhang
authors.forename: H-F
authors.initials: HF
authors.lastname: Pi
authors.forename: W-L
authors.initials: WL
authors.lastname: Xiao
authors.forename: H-D
authors.initials: HD
authors.lastname: Sun
authors.forename: J-Z
authors.initials: JZ
authors.lastname: Wu
mesh_terms: D000818:Animals; D000972:Antineoplastic Agents, Phytogenic / Q000302:isolation & purification*; D006801:Humans; D029069:Impatiens / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D051379:Mice; D008807:Mice, Inbred BALB C; D027343:Rhizome / Q000737:chemistry*; D012503:Saponins / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
chemical_list: C525311:3-O-((6-O-ethyl)glucuronopyranosyl)echinocystic acid; C525313:3-O-((6-O-n-butyl)glucuronopyranosyl)-28-O-(xylopyranosyl-1-4-rhamnopyranosyl-1-2-xylopyranosyl)echinocystic acid; C525312:3-O-((6-O-n-butyl)glucuronopyranosyl)echinocystic acid; D000972:Antineoplastic Agents, Phytogenic; D012503:Saponins; D014315:Triterpenes