[Role of cell adhesion molecules in the modulation of synaptic activity].
Cell adhesion molecules (CAMs) can influence various developmental events, including cell migration, proliferation, and differentiation. Recent advances have provided evidence that in addition to their adhesive properties, CAMs can affect intracellular signalling and synaptic function. This review focuses on the role of CAMs in the modulation of synaptic activity. Some mechanisms are being discussed including one that involve the ability of CAMs to initiate the formation of scaffolds permitting efficient signalling.
Nikonenko
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Skybo
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D000818:Animals; D015815:Cell Adhesion Molecules / Q000502:physiology*; D006801:Humans; D009473:Neuronal Plasticity; D009474:Neurons / Q000378:metabolism / Q000502:physiology*; D009435:Synaptic Transmission / Q000502:physiology*
D015815:Cell Adhesion Molecules