Rapidly expanding brain mass.
Amebic encephalitis is an uncommon central nervous system infection, usually caused by Acanthamoeba spp., which generally occurs in immunocompromised individuals. The infection might start from a minor, slowly progressive, skin ulceration that can be present for weeks to months before neurologic changes occur. We present a 40-year-old male with multiple visceral allografts, on immunosuppression, 9 months after transplantation. He had an active skin rash previously diagnosed as graft-versus-host disease by biopsy. The condition of the patient declined rapidly.
Gene
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Department of Pathology, Hospital Universitario Son Dureta, Palma de Mallorca, Spain.
Gardner
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PA
Couce Matovelle
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ME
D000048:Acanthamoeba / Q000302:isolation & purification*; D000328:Adult; D000562:Amebiasis / Q000175:diagnosis* / Q000276:immunology; D000818:Animals; D003937:Diagnosis, Differential; D004660:Encephalitis / Q000276:immunology / Q000469:parasitology*; D017809:Fatal Outcome; D005736:Gardner Syndrome / Q000209:etiology / Q000601:surgery; D006801:Humans; D016867:Immunocompromised Host; D007165:Immunosuppression Therapy / Q000009:adverse effects; D008297:Male; D014184:Transplantation, Homologous / Q000009:adverse effects* / Q000276:immunology