title: Low-power transpupillary thermotherapy combined with intravitreal triamcinolone acetonide for subfoveal choroidal neovascularization.
abstract: OBJECTIVE
  To examine transpupillary thermotherapy combined with intravitreal triamcinolone for treatment of subfoveal choroidal neovascularization.
  
  
  METHODS
  The clinical interventional, noncomparative, case series study included 14 patients (14 eyes) with choroidal neovascularization (age-related macular degeneration, n = 11; high myopia, n = 2; unknown reason, n = 1), who underwent transpupillary thermotherapy (75-150 mW, 60 s, 500-3,000 microm), followed by an intravitreal triamcinolone injection (10 mg). Follow-up was at least 6 months.
  
  
  RESULTS
  Visual acuity increased by 3 lines in 3 (21%) eyes at 3 months, and in 3 (21%) eyes at 6 months of follow-up. None of the patients experienced a visual acuity loss of 3 or more lines. At the 6-month follow-up, mean visual acuity was improved by 1.36 +/- 1.16 lines. Retreatment by transpupillary thermotherapy was performed for 3 (21%) eyes at 3 months, and for 1 (7%) eye at 6 months of follow-up.
  
  
  CONCLUSIONS
  Transpupillary thermotherapy combined with intravitreal triamcinolone may be a therapeutic option for choroidal neovascularization particularly if other treatment modalities are not available.
authors.affiliation: Beijing Institute of Ophthalmology, Department of Ophthalmology and Eye Hospital, Tongren Hospital, Capital University of Medical Science, Beijing, China.
authors.forename: Xinyuan
authors.initials: X
authors.lastname: Zhang
authors.forename: Xiaoqing
authors.initials: X
authors.lastname: Zhu
authors.forename: Dongsheng
authors.initials: D
authors.lastname: Wang
authors.forename: Liang
authors.initials: L
authors.lastname: Xu
authors.forename: Jost B
authors.initials: JB
authors.lastname: Jonas
mesh_terms: D020256:Choroidal Neovascularization / Q000503:physiopathology / Q000628:therapy*; D005500:Follow-Up Studies; D005584:Fovea Centralis; D005938:Glucocorticoids / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D006979:Hyperthermia, Induced / Q000379:methods; D007267:Injections; D011680:Pupil; D019233:Retreatment; D016896:Treatment Outcome; D014222:Triamcinolone Acetonide / Q000008:administration & dosage / Q000627:therapeutic use*; D014792:Visual Acuity; D014822:Vitreous Body
chemical_list: D005938:Glucocorticoids; D014222:Triamcinolone Acetonide