Tissue engineering and tissue repair in immunocompetent animals: tissue construction and repair.
Tissue engineering can regenerate autologous tissue using a biodegradable scaffold and in vitro expanded cells derived from small biopsy samples, and thus may have great potential for tissue repair and reconstruction in plastic and reconstructive surgery. As an important step towards a clinical application, research work in large animals is essential. This article presents our experience of tissue engineering and repair in large animals in the areas of bone, cartilage and tendon.
Cao
Y
Y
Department of Plastic and Reconstructive Surgery, Shanghai 9th People's Hospital, National Tissue Engineering Center of China, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China. yilincao@yahoo.com
Liu
W
W
Zhou
G
G
Cui
L
L
D000818:Animals; D016025:Bone Transplantation / Q000276:immunology / Q000379:methods; D002356:Cartilage / Q000276:immunology / Q000637:transplantation; D002645:Chickens; D004285:Dogs; D007121:Immunocompetence; D019651:Plastic Surgery Procedures / Q000379:methods*; D012756:Sheep; D013552:Swine; D013710:Tendons / Q000276:immunology / Q000637:transplantation; D023822:Tissue Engineering / Q000379:methods*