Issues unique to pediatric liver transplantation.
Liver transplantation in pediatrics has become an accepted modality of treatment in end-stage liver disease and irreversible acute liver failure. Biliary atresia is the most common indication requiring liver transplantation in children. The diagnosis and causes of acute liver failure in children differ from those in adults. Growth and development require special consideration in children. Regular surveillance of Epstein-Barr virus by polymerase chain reaction and appropriate therapy may reduce the incidence of post-transplant lymphoproliferative disease after transplantation. Adherence to the prescribed medical regimen is essential for good graft function. A multidisciplinary approach is the key to success in liver transplantation in children.
Kerkar
Nanda
N
Division of Pediatric Hepatology, Department of Pediatrics, Mount Sinai School of Medicine, Box 1104, New York, NY 10029, USA.
Emre
Sukru
S
D000328:Adult; D002648:Child; D000075202:Contraindications; D006801:Humans; D007165:Immunosuppression Therapy; D007223:Infant; D008107:Liver Diseases / Q000209:etiology / Q000601:surgery*; D016031:Liver Transplantation / Q000009:adverse effects; D010349:Patient Compliance; D018579:Patient Selection; D019737:Transplants / Q000600:supply & distribution