title: Allele frequency distribution for 15 autosomal STR loci in two Muslim populations of Tamilnadu, India.
abstract: Allele frequencies of the 15 autosomal STR loci: D8S1179, D21S11, D7S820, CSF1PO, D19S433, vWA, TPOX, D18S51, D3S1358, THO1, D13S317, D16S539, D2S1338, D5S818, and FGA were determined in two endogamous Muslim populations (Dawoodi Bohra Muslims from Shiite Muslims and Sunni Muslims) residing in Tamilnadu, India. The Loci D7S820, CSF1PO, D19S433, vWA, TPOX, D13S317, D16S539, D5S818, and FGA in Dawoodi Bohra Muslims from Shiite Muslims, and CSF1PO, D19S433, TPOX, and D16S539 in Sunni Muslims were found to deviate significantly from Hardy-Weinberg equilibrium. The power of discrimination of the analyzed markers was found to be high for the populations, thereby facilitating the validation and efficiency of these STR markers in human identification.
authors.affiliation: National DNA Analysis Center, Directorate of Forensic Science, Central Forensic Science Laboratory, 30, Gorachand Road, Kolkata 700 014, India.
authors.forename: M
authors.initials: M
authors.lastname: Eaaswarkhanth
authors.forename: Soma
authors.initials: S
authors.lastname: Roy
authors.forename: Ikramul
authors.initials: I
authors.lastname: Haque
mesh_terms: D044466:Asian People / Q000235:genetics*; D001800:Blood Specimen Collection; D016172:DNA Fingerprinting; D005787:Gene Frequency; D006580:Genetic Carrier Screening; D005828:Genetics, Population / Q000379:methods*; D005838:Genotype; D006801:Humans; D007194:India; D007514:Islam; D018895:Microsatellite Repeats / Q000235:genetics*; D016133:Polymerase Chain Reaction; D017422:Sequence Analysis, DNA / Q000379:methods