title: Intracranial hemorrhage sparing meningioma in an anticoagulated patient.
abstract: OBJECTIVE
  The risk of intracerebral hemorrhage (ICH) in patients receiving antithrombotic therapy is well known. However, there is sparse literature regarding the risk of intracerebral hemorrhage in patients receiving warfarin, who have an intracranial meningioma.
  
  
  RESULTS
  We report a case of a 66-year-old man who developed multifocal ICHs in the context of supratherapeutic anticoagulation. There was sparing of the intracranial meningioma despite the development and growth of multiple intraparenchymal hemorrhages that resulted in death. We also review the literature evaluating the risk of ICH in anticoagulated patients with an intracranial meningioma.
  
  
  CONCLUSIONS
  The findings of this case lend further support to the gradually developing notion of relative safety of anticoagulation in patients with meningioma. They also underscore the importance of close monitoring of the INR.
authors.affiliation: Department of Neurology, Boston University Medical Center, Boston, Massachusetts 02118, USA. joromero@bmc.org
authors.forename: José Rafael
authors.initials: JR
authors.lastname: Romero
authors.forename: Osamu
authors.initials: O
authors.lastname: Sakai
authors.forename: Mary Berlik
authors.initials: MB
authors.lastname: Rice
authors.forename: Viken L
authors.initials: VL
authors.lastname: Babikian
mesh_terms: D000368:Aged; D000925:Anticoagulants / Q000009:adverse effects; D001932:Brain Neoplasms / Q000000981:diagnostic imaging; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D006801:Humans; D020300:Intracranial Hemorrhages / Q000139:chemically induced* / Q000000981:diagnostic imaging*; D008297:Male; D008579:Meningioma / Q000000981:diagnostic imaging; D014057:Tomography, X-Ray Computed; D014859:Warfarin / Q000009:adverse effects
chemical_list: D000925:Anticoagulants; D014859:Warfarin