Design of a novel inherently chiral calix[4]arene for chiral molecular recognition.
A newly designed inherently chiral calix[4]arene was synthesized and resolved to an optically pure form. Enantiomeric recognition ability of the chiral calix[4]arene was examined using 1H NMR experiments with mandelic acid. In addition, the chiral calix[4]arene was applied to asymmetric reactions, as an organocatalyst.
Shirakawa
Seiji
S
Department of Applied Molecular Chemistry and High Technology Research Center, College of Industrial Technology, Nihon University, Narashino, Chiba, 275-8575, Japan.
Moriyama
Akihiro
A
Shimizu
Shoichi
S
D047250:Calixarenes / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D009682:Magnetic Resonance Spectroscopy; D008333:Mandelic Acids / Q000737:chemistry; D015394:Molecular Structure; D010636:Phenols / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
D008333:Mandelic Acids; D010636:Phenols; C121325:calix(4)arene; D047250:Calixarenes; C037938:mandelic acid