[Low-dose rate brachytherapy with locally integrated beta emitters after internal urethrotomy. A pilot project using an animal model].
BACKGROUND
The treatment of urethral strictures represents an unsolved urological problem.


METHODS
The effect of a (32)P-coated urethral catheter in the sense of low-dose rate brachytherapy to modulate wound healing will be analyzed in an animal experiment.


RESULTS
Unfortunately it is not possible to present any results because this is being studied for the first time and there are no experiences with low-dose rate brachytherapy and this form of application in the lower urinary tract. Furthermore the animal experiment will only start in the near future. Both decade-long experiences with radiotherapy to treat benign diseases and our own results of previous studies in otolaryngology and ophthalmology let us expect a significantly lower formation of urethral strictures after internal urethrotomy.


CONCLUSIONS
This study will contribute to improving the treatment of urethral strictures as demanded in previous papers.
Weidlich
P
P
Urologische Klinik und Poliklinik, Klinikum der Universität München-Grosshadern, Marchioninistrasse 15, 81377 München. Patrick.Weidlich@med.uni-muenchen.de
Adam
C
C
Sroka
R
R
Lanzl
I
I
Assmann
W
W
Stief
C
C
D000818:Animals; D001610:Beta Particles / Q000627:therapeutic use; D001918:Brachytherapy / Q000379:methods*; D002408:Catheters, Indwelling; D004195:Disease Models, Animal; D008297:Male; D010761:Phosphorus Radioisotopes / Q000627:therapeutic use; D011817:Rabbits; D011879:Radiotherapy Dosage; D012008:Recurrence; D041623:Tomography, Optical Coherence; D014521:Urethra / Q000473:pathology / Q000528:radiation effects; D014525:Urethral Stricture / Q000473:pathology / Q000532:radiotherapy*
D010761:Phosphorus Radioisotopes