title: Basidiomycetous fungal Inonotus tropicalis sacral osteomyelitis in X-linked chronic granulomatous disease.
abstract: Osteomyelitis is a common clinical manifestation of chronic granulomatous disease, a disorder of phagocytic function. Fungal organisms account for a significant proportion of these infections. We describe the clinical presentation and subsequent destructive sacral osteomyelitis with a basidiomycetous mold, Inonotus tropicalis, in a patient with an X-linked chronic granulomatous disease.
authors.affiliation: Division of Allergy and Immunology, Department of Pediatrics, Baylor College of Medicine, Houston, Texas 77030, USA. cmdavis@texaschildrenshospital.org
authors.forename: Carla M
authors.initials: CM
authors.lastname: Davis
authors.forename: Lenora M
authors.initials: LM
authors.lastname: Noroski
authors.forename: Megan K
authors.initials: MK
authors.lastname: Dishop
authors.forename: Deanna A
authors.initials: DA
authors.lastname: Sutton
authors.forename: Richard M
authors.initials: RM
authors.lastname: Braverman
authors.forename: Mary E
authors.initials: ME
authors.lastname: Paul
authors.forename: Howard M
authors.initials: HM
authors.lastname: Rosenblatt
mesh_terms: D000328:Adult; D000935:Antifungal Agents / Q000627:therapeutic use; D001487:Basidiomycota / Q000302:isolation & purification*; D000077336:Caspofungin; D054714:Echinocandins; D006105:Granulomatous Disease, Chronic / Q000150:complications*; D024243:HMGB1 Protein / Q000627:therapeutic use; D006801:Humans; D055666:Lipopeptides; D008297:Male; D009181:Mycoses / Q000188:drug therapy* / Q000382:microbiology*; D010019:Osteomyelitis / Q000382:microbiology*; D010456:Peptides, Cyclic / Q000627:therapeutic use; D011743:Pyrimidines / Q000627:therapeutic use; D012447:Sacrum / Q000382:microbiology / Q000473:pathology; D014230:Triazoles / Q000627:therapeutic use; D065819:Voriconazole
chemical_list: D000935:Antifungal Agents; D054714:Echinocandins; D024243:HMGB1 Protein; D055666:Lipopeptides; D010456:Peptides, Cyclic; D011743:Pyrimidines; D014230:Triazoles; D000077336:Caspofungin; D065819:Voriconazole