title: [Peri-implantitis or squamous cell carcinoma?].
abstract: BACKGROUND
  Squamous cell carcinoma developed around dental implants has seldom been described. It simulates peri-implantitis. The authors present two cases and a literature review.
  
  
  METHODS
  A 70 year-old woman presented with an exophytic tumor developed around dental implants placed in the anterior part of the mandible. Panoramic X-rays showed major osteolysis, especially around the distal abutment implants. A 72 year-old patient, smoker, presented with chronic lichen planus; he was carrying two implants supporting an overdenture with ball-attachments, placed 15 years before. He presented with an ulcerated symphyseal tumor, bone loss around implant in position 43. The implant had been spontaneously pushed out. In both cases the diagnosis was squamous cell carcinoma.
  
  
  CONCLUSIONS
  Few cases of squamous cell carcinoma developed around dental implants have been reported. They initially mimic peri-implantitis. The carcinogenic role of the implant has never been established. Another hypothesis is the migration of malignant cells, originating from a mucosal tumor, through the sulcus. Risk factors for squamous cell carcinoma (smoking or alcohol consumption, precancerous lesions) are an indication for a permanent follow-up. Biopsies will prove the diagnosis.
authors.affiliation: Department of Oral and Maxillofacial Surgery, Rambam Medical Center, Technion Faculty of Medicine, Haifa, Israel.
authors.forename: I
authors.initials: I
authors.lastname: Abu El-Naaj
authors.forename: O
authors.initials: O
authors.lastname: Trost
authors.forename: N
authors.initials: N
authors.lastname: Tagger-Green
authors.forename: P
authors.initials: P
authors.lastname: Trouilloud
authors.forename: N
authors.initials: N
authors.lastname: Robe
authors.forename: G
authors.initials: G
authors.lastname: Malka
authors.forename: M
authors.initials: M
authors.lastname: Peled
mesh_terms: D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000209:etiology / Q000473:pathology*; D015921:Dental Implants / Q000009:adverse effects*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D017676:Lichen Planus, Oral / Q000150:complications; D008297:Male; D008339:Mandibular Neoplasms / Q000209:etiology / Q000473:pathology*; D010014:Osteolysis / Q000209:etiology; D010518:Periodontitis / Q000175:diagnosis* / Q000209:etiology
chemical_list: D015921:Dental Implants