The combined effects of capsaicin, green tea extract and chicken essence tablets on human autonomic nervous system activity.
The purpose of this study was to investigate whether combined capsaicin, green tea, and chicken essence tablets (CCGC) enhance human autonomic nervous activities (ANS) associated with thermogenic sympathetic activity without any adverse effect on the cardiac depolarization-repolarization period. Six healthy males (25.2 +/-1.7 y) volunteered for this experiment. Autonomic nervous activities were examined 5-min at rest per 30-min for total 1.5 h after consuming chicken or CCGC or placebo tablets at random on separate days. Using heart rate variability power spectral analysis, we assessed human autonomic nervous activities. In comparison to chicken essence or placebo tablets, it was observed that the consumption of CCGC significantly increased human autonomic nervous activities [Total power representing over-all ANS activity; CCGC trial 160.2 (50.0) vs. placebo 92.8 (53.3)%, p < 0.05; VLF, very low-frequency power associated with thermogenic sympathetic activity: CCGC trial 235.5 (101.7) vs. chicken 130.5 (52.9)%, p < 0.05; LF, low frequency power representing combined sympatho-vagal activity: CCGC trial 199.8 (59.8) vs. placebo 120.6 (49.2)%, p < 0.05] at 60-min and 90-min. There were no significant differences in heart rate corrected cardiac recovery time (RTc) or QT interval (QTc). In conclusion, the consumption of CCGC enhances thermogenic sympathetic activity compared to that of chicken essence or placebo tablets. Therefore, these results suggest that combined capsaicin, green tea, and chicken essence tablets may be a beneficial food ingredient improving human autonomic nervous activities, particularly thermogenic sympathetic activity as a modulator of energy metabolism without any adverse effects on cardiac electrical stability.
Shin
Ki Ok
KO
Laboratory of Applied Physiology, Graduate School of Human and Environmental Studies, Kyoto University, Kyoto 606-8501, Japan.
Moritani
Toshio
T
D000328:Adult; D018712:Analgesics, Non-Narcotic / Q000494:pharmacology; D000818:Animals; D001341:Autonomic Nervous System / Q000187:drug effects*; D028241:Camellia sinensis; D002211:Capsaicin / Q000494:pharmacology*; D002645:Chickens; D004032:Diet / Q000379:methods; D004734:Energy Metabolism / Q000187:drug effects; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D008297:Male; D010936:Plant Extracts / Q000494:pharmacology*; D011202:Poultry Products; D012016:Reference Values; D013607:Tablets; D013662:Tea; D022722:Thermogenesis / Q000187:drug effects; D013997:Time Factors
D018712:Analgesics, Non-Narcotic; D010936:Plant Extracts; D013607:Tablets; D013662:Tea; D002211:Capsaicin