title: Tick acquisition of Ehrlichia canis from dogs treated with doxycycline hyclate.
abstract: Doxycycline generally alleviates clinical monocytic ehrlichiosis, but its efficacy in the control of monocytotropic ehrlichial pathogens requires further investigation. In this study, Ehrlichia canis was detected in dogs treated with doxycycline for 14 days and in ticks fed on these dogs, suggesting that treated dogs can remain reservoirs for E. canis.
authors.affiliation: Department of Veterinary Preventive Medicine, The Ohio State University, Columbus, Ohio 43210, USA.
authors.forename: John J
authors.initials: JJ
authors.lastname: Schaefer
authors.forename: Glen R
authors.initials: GR
authors.lastname: Needham
authors.forename: William G
authors.initials: WG
authors.lastname: Bremer
authors.forename: Yasuko
authors.initials: Y
authors.lastname: Rikihisa
authors.forename: S A
authors.initials: SA
authors.lastname: Ewing
authors.forename: R W
authors.initials: RW
authors.lastname: Stich
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D001096:Arachnid Vectors; D004283:Dog Diseases / Q000188:drug therapy* / Q000382:microbiology; D004285:Dogs; D004318:Doxycycline / Q000031:analogs & derivatives* / Q000627:therapeutic use; D041061:Ehrlichia canis; D016873:Ehrlichiosis / Q000188:drug therapy* / Q000382:microbiology / Q000662:veterinary*; D020133:Reverse Transcriptase Polymerase Chain Reaction; D048508:Rhipicephalus sanguineus / Q000254:growth & development / Q000382:microbiology*
chemical_list: D000900:Anti-Bacterial Agents; D004318:Doxycycline