Modular syntheses of multidentate ligands with variable N-donors: applications to tri- and tetracopper(I) complexes.
A general method for the preparation of multidentate ligands comprised of a multi-imine platform derived from 1,1,1-tris(aminomethyl)ethane or tris(aminoethyl)amine connected to bi- and tridentate N-donor chelates has been developed. The feasibility of the method has been demonstrated through the synthesis and characterization of a large set of these ligand types. Complexation to Cu(I) was accomplished for several cases, yielding tri- and tetracopper(I) complexes that have been characterized in solution by NMR spectroscopy and conductivity, and in the solid state by elemental analysis, mass spectrometry, and/or X-ray crystallography. These complexes are potentially useful for modeling multicopper protein active sites.
Brown
Eric C
EC
Department of Chemistry and Center for Metals in Biocatalysis, University of Minnesota, 207 Pleasant St. SE, Minneapolis, MN 55455, USA.
Johnson
Brandon
B
Palavicini
Sara
S
Kucera
Benjamin E
BE
Casella
Luigi
L
Tolman
William B
WB
D003300:Copper / Q000737:chemistry*; D018360:Crystallography, X-Ray; D004553:Electric Conductivity; D008024:Ligands; D008958:Models, Molecular; D015394:Molecular Structure; D009584:Nitrogen / Q000737:chemistry*
D008024:Ligands; D003300:Copper; D009584:Nitrogen