title: In vitro antioxidative activities of three marine oligosaccharides.
abstract: The antioxidant activities of three marine oligosaccharides, alginate oligosaccharides (AOs), chitosan oligosaccharides (COs), and fucoidan oligosaccharides (FOs), were investigated in vitro by several antioxidant assays, including hydroxyl radical scavenging, superoxide radical scavenging, erythrocyte hemolysis inhibiting, metal chelating activities, and anti-lipid peroxidation. The results show that these oligosaccharides exhibited different activities in various assays. AOs had the highest scavenging hydroxyl radical activity than FOs and COs at all the tested amounts. COs had the highest scavenging superoxide radical and inhibiting erythrocyte hemolysis activity than AOs and FOs at all the tested amounts. In the assay of chelating Fe2+, COs and FOs indicated good chelation while AOs hardly had any activity. In the assay of anti-lipid peroxidation, only COs had significantly high antioxidant activity.
authors.affiliation: Department of Food Science and Engineering, Division of Life Science and Technology, Ocean University of China, Qingdao 266003, PR China. prichard889@msn.com
authors.forename: Peng
authors.initials: P
authors.lastname: Wang
authors.forename: Xiaolu
authors.initials: X
authors.lastname: Jiang
authors.forename: Yanhua
authors.initials: Y
authors.lastname: Jiang
authors.forename: Xiaoke
authors.initials: X
authors.lastname: Hu
authors.forename: Haijin
authors.initials: H
authors.lastname: Mou
authors.forename: Man
authors.initials: M
authors.lastname: Li
authors.forename: Huashi
authors.initials: H
authors.lastname: Guan
mesh_terms: D000464:Alginates / Q000737:chemistry / Q000494:pharmacology; D000818:Animals; D000975:Antioxidants / Q000737:chemistry* / Q000494:pharmacology; D048271:Chitosan / Q000737:chemistry / Q000494:pharmacology; D004912:Erythrocytes / Q000187:drug effects; D016166:Free Radical Scavengers / Q000737:chemistry / Q000494:pharmacology; D006461:Hemolysis / Q000187:drug effects; D017665:Hydroxyl Radical / Q000737:chemistry; D007502:Iron Chelating Agents / Q000737:chemistry; D008054:Lipid Peroxides / Q000737:chemistry; D009844:Oligosaccharides / Q000737:chemistry* / Q000494:pharmacology*; D011134:Polysaccharides / Q000737:chemistry / Q000494:pharmacology; D051381:Rats; D013481:Superoxides / Q000737:chemistry
chemical_list: D000464:Alginates; D000975:Antioxidants; D016166:Free Radical Scavengers; D007502:Iron Chelating Agents; D008054:Lipid Peroxides; D009844:Oligosaccharides; D011134:Polysaccharides; D013481:Superoxides; D017665:Hydroxyl Radical; D048271:Chitosan; C007789:fucoidan