title: Indium(III) trifluoromethanesulfonate as an efficient catalyst for the deprotection of acetals and ketals.
abstract: Acetals and ketals are readily deprotected under neutral conditions in the presence of acetone and catalytic amounts of indium(III) trifluoromethanesulfonate (<0.8 mol %) at room temperature or mild microwave heating conditions to give the corresponding aldehydes and ketones in good to excellent yields.
authors.affiliation: Department of Medicinal Chemistry, AMRI, Albany, NY 12203, USA. brian.gregg@amriglobal.com
authors.forename: Brian T
authors.initials: BT
authors.lastname: Gregg
authors.forename: Kathryn C
authors.initials: KC
authors.lastname: Golden
authors.forename: John F
authors.initials: JF
authors.lastname: Quinn
mesh_terms: D000080:Acetals / Q000737:chemistry*; D002384:Catalysis; D009682:Magnetic Resonance Spectroscopy; D009942:Organometallic Compounds / Q000737:chemistry*; D021241:Spectrometry, Mass, Electrospray Ionization
chemical_list: D000080:Acetals; C522942:Indium(III) trifluoromethanesulfonate; D009942:Organometallic Compounds