Molecular characterization of the glycoprotein genes of H5N1 influenza A viruses isolated in Israel and the Gaza Strip during 2006 outbreaks.
Highly pathogenic H5N1 avian influenza A viruses (AIV) have caused outbreaks among domestic poultry and wild aquatic birds in many Asian, European, and African countries since 1997. In March 2006 an avian H5N1 influenza A virus was isolated from poultry in Israel. In the present study we molecularly characterized the hemagglutinin (HA) and neuraminidase (NA) genes of eleven H5N1 viruses isolated from domestic poultry in Israel and Gaza in March-April 2006. Phylogenetic analysis of the HA and NA genes showed that the Israeli and Gazian viruses were closely related to viruses isolated in Egypt in 2006.
Perk
Shimon
S
Division of Avian and Aquatic Diseases, Kimron Veterinary Institute, POB 12, Beit Dagan 50250, Israel.
Banet-Noach
Caroline
C
Golender
Natalia
N
Simanov
Lubov
L
Rozenblut
Ezra
E
Nagar
Sagit
S
Pokamunski
Shimon
S
Pirak
Michael
M
Tendler
Yevgenii
Y
García
Maricarmen
M
Panshin
Alexander
A
D000818:Animals; D004196:Disease Outbreaks; D019267:Hemagglutinin Glycoproteins, Influenza Virus / Q000235:genetics*; D053124:Influenza A Virus, H5N1 Subtype / Q000145:classification* / Q000235:genetics* / Q000302:isolation & purification; D005585:Influenza in Birds / Q000453:epidemiology / Q000821:virology*; D007557:Israel / Q000453:epidemiology; D008877:Middle East / Q000453:epidemiology; D017720:Molecular Epidemiology; D008969:Molecular Sequence Data; D009439:Neuraminidase / Q000235:genetics*; D010802:Phylogeny; D011200:Poultry; D017422:Sequence Analysis, DNA; D017385:Sequence Homology; D014764:Viral Proteins / Q000235:genetics*
D019267:Hemagglutinin Glycoproteins, Influenza Virus; D014764:Viral Proteins; C109963:hemagglutinin, avian influenza A virus; C487630:NA protein, influenza A virus; D009439:Neuraminidase