title: Anisotropy of the backscatter coefficient of formalin-fixed ovine myocardium.
abstract: The objective of this study was to measure the backscatter coefficient of formalin-fixed myocardial tissue as a function of angle of insonification relative to the myocardial fiber direction. Backscatter measurements were performed on eight cylindrical formalin-fixed lamb myocardial specimens and compensated for attenuation and diffraction effects to determine the backscatter coefficient. The backscatter coefficient at 5 MHz was found to be maximum for insonification perpendicular to the predominant myofiber orientation and minimum for parallel insonification, with values of (17+/-14) and (1.2+/-0.7) x 10(-4) cm(-1) sr(-1) (mean+/-standard deviation), respectively.
authors.affiliation: Department of Physics, Washington University, St. Louis, Missouri 63130, USA.
authors.forename: Min
authors.initials: M
authors.lastname: Yang
authors.forename: Todd M
authors.initials: TM
authors.lastname: Krueger
authors.forename: Mark R
authors.initials: MR
authors.lastname: Holland
authors.forename: James G
authors.initials: JG
authors.lastname: Miller
mesh_terms: D000818:Animals; D016880:Anisotropy; D004452:Echocardiography; D005404:Fixatives; D005557:Formaldehyde; D009206:Myocardium; D012756:Sheep; D016707:Tissue Fixation / Q000379:methods*
chemical_list: D005404:Fixatives; D005557:Formaldehyde