Inherited factor XI deficiency: a concise review.
Inherited factor XI (FXI) deficiency, also called Hemophilia C, is an uncommon autosomal recessive disorder, which is associated with a variable bleeding tendency that usually manifests after trauma or surgery. This concise report reviews current knowledge regarding the pathogenesis, genetics, diagnosis, clinical manifestations and management of this inherited bleeding disorder.
Franchini
Massimo
M
Servizio di Immunoematologia e Trasfusione - Centro Emofilia, Azienda Ospedaliera di Verona, Italy.
Veneri
Dino
D
Lippi
Giuseppe
G
D025861:Blood Coagulation Disorders, Inherited; D019468:Disease Management; D005173:Factor XI Deficiency / Q000175:diagnosis / Q000209:etiology / Q000628:therapy; D006470:Hemorrhage / Q000209:etiology; D006801:Humans