The mitogen-activated protein kinase pathway for molecular-targeted cancer treatment.
Sebolt-Leopold
Judith S
JS
Pfizer Global Research and Development, Michigan Laboratories, Ann Arbor 48105, USA.
Herrera
Roman
R
Ohren
Jeffrey F
JF
D000970:Antineoplastic Agents / Q000737:chemistry / Q000494:pharmacology* / Q000627:therapeutic use; D002986:Clinical Trials as Topic; D018450:Disease Progression; D004354:Drug Screening Assays, Antitumor; D006801:Humans; D020928:Mitogen-Activated Protein Kinases / Q000037:antagonists & inhibitors* / Q000737:chemistry / Q000378:metabolism*; D009369:Neoplasms / Q000188:drug therapy* / Q000201:enzymology*; D011487:Protein Conformation; D047428:Protein Kinase Inhibitors / Q000737:chemistry / Q000494:pharmacology* / Q000627:therapeutic use; D015398:Signal Transduction
D000970:Antineoplastic Agents; D047428:Protein Kinase Inhibitors; D020928:Mitogen-Activated Protein Kinases