title: Plasmodium vivax infection among Duffy antigen-negative individuals from the Brazilian Amazon region: an exception?
abstract: We present evidence for Plasmodium vivax infection among Duffy blood group-negative inhabitants of Brazil. The P. vivax identification was determined by both genotypic and non-genotypic screening tests. The Duffy blood group was genotyped by PCR/RFLP and phenotyped using a microtyping kit. We detected two homozygous FY*B-33 carriers infected by P. vivax, whose circumsporozoite protein genotypes were VK210 and/or P. vivax-like. Additional efforts are necessary in order to clarify the evidence that P. vivax is being transmitted among Duffy blood group-negative patients from the Brazilian Amazon region.
authors.affiliation: Faculty of Medicine, São José do Rio Preto, Av. Brigadeiro Faria Lima 5416, 15090-000 São José do Rio Preto, São Paulo State, Brazil. cecavasini@famerp.br
authors.forename: Carlos Eugênio
authors.initials: CE
authors.lastname: Cavasini
authors.forename: Luiz Carlos de
authors.initials: LC
authors.lastname: Mattos
authors.forename: Alvaro Augusto D'Almeida
authors.initials: AA
authors.lastname: Couto
authors.forename: Cláudia Regina
authors.initials: CR
authors.lastname: Bonini-Domingos
authors.forename: Socrates Herrera
authors.initials: SH
authors.lastname: Valencia
authors.forename: Wanessa Christina de Souza
authors.initials: WC
authors.lastname: Neiras
authors.forename: Renata Tomé
authors.initials: RT
authors.lastname: Alves
authors.forename: Andréa Regina Baptista
authors.initials: AR
authors.lastname: Rossit
authors.forename: Lilian
authors.initials: L
authors.lastname: Castilho
authors.forename: Ricardo Luiz Dantas
authors.initials: RL
authors.lastname: Machado
mesh_terms: D001938:Brazil / Q000453:epidemiology; D004375:Duffy Blood-Group System / Q000235:genetics / Q000276:immunology*; D005260:Female; D006801:Humans; D016780:Malaria, Vivax / Q000097:blood / Q000453:epidemiology / Q000276:immunology*; D008297:Male
chemical_list: D004375:Duffy Blood-Group System