Combinatorial synthesis, reversed-phase and normal-phase high-performance liquid chromatography elution data and liquid chromatography/positive atmospheric pressure chemical ionization tandem mass spectra of methoxylated and glycosylated resveratrol analogues.
Analyses of methoxylated and glycosylated stilbenes remain scarce in the literature because of the commercial unavailability of these compounds. Here a library of 22 compounds was synthesized by combinatorial chemistry. Their elution profiles were compared on three different columns (C18, C8, and silica) with those of seven commercial resveratrol analogues and two viniferins. The spectra recorded by liquid chromatography/positive atmospheric pressure chemical ionization tandem mass spectrometry (LC-APCI(+)-MS/MS) are discussed and recommendations made for easier identification of new stilbenes.
Jerkovic
Vesna
V
Unité de Brasserie et des Industries Alimentaires, Faculté d'Ingénierie biologique, agronomique et environnementale, Université catholique de Louvain, Croix du Sud, 2 bte 7, B-1348 Louvain-la-Neuve, Belgium.
Nguyen
Fanny
F
Nizet
Sabrina
S
Collin
Sonia
S
D000972:Antineoplastic Agents, Phytogenic / Q000032:analysis / Q000737:chemistry*; D001272:Atmosphere; D002851:Chromatography, High Pressure Liquid; D020650:Combinatorial Chemistry Techniques / Q000379:methods; D006031:Glycosylation; D010636:Phenols / Q000032:analysis / Q000737:chemistry*; D000077185:Resveratrol; D021241:Spectrometry, Mass, Electrospray Ionization / Q000379:methods*; D013267:Stilbenes / Q000032:analysis / Q000737:chemistry*; D053719:Tandem Mass Spectrometry / Q000379:methods*
D000972:Antineoplastic Agents, Phytogenic; D010636:Phenols; D013267:Stilbenes; D000077185:Resveratrol