[Biogenic amines during intoxication with phenol and correction with the liquid oxygen in the experiment].
Among many toxic substances present in the nature, phenol represents one of those, which may be considered as the endocrinological deregulator. We were conducting experiment on 40 male rats every day influencing by inhalation of the vapor of the phenol, as they laid on the thigh, at the second stage after the inhalation we were making injections of the liquid oxygen under the skin to each rats for the purpose of treatment. After we produced the decapitation of the animals under general narcoses, we took the hypothalamus and investigated concentrations of biogenic amines - dopamine, noradrenalin and serotonin. It was shown that in response to the inhalation of the phenol concentration of the biogenic amines has been abolished in comparison with the norm. The liquid oxygen gave the therapeutic effect.
Melikadze
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EB
D000818:Animals; D000931:Antidotes / Q000008:administration & dosage*; D001679:Biogenic Amines / Q000032:analysis / Q000378:metabolism*; D007031:Hypothalamus / Q000737:chemistry / Q000187:drug effects / Q000378:metabolism*; D008297:Male; D010100:Oxygen / Q000008:administration & dosage*; D019800:Phenol / Q000037:antagonists & inhibitors* / Q000506:poisoning*; D051381:Rats; D011919:Rats, Inbred Strains
D000931:Antidotes; D001679:Biogenic Amines; D019800:Phenol; D010100:Oxygen