title: Gender- and age-related variations in blood viscosity in normal volunteers: a study of the effects of extract of Allium sativum and Ginkgo biloba.
abstract: This study sought to compare the effects of age and gender on blood viscosity and to appraise the effectiveness of Ginkgo biloba and Allium sativum extracts in reducing blood viscosity. Stage 1: Our sample consisted of 80 male volunteers (40 aged 18-60 and 40 aged 61 and over) and 80 females with the same age profile. Stage 2: We studied 60 male volunteers allocated in groups: placebo, G. biloba, and A. sativum. Stage 3: We studied 25 male volunteers and in the initial, intermediate, and final evaluations, the measures of blood viscosity were repeated. Volunteers were given a clinical evaluation and submitted to laboratory tests. G. biloba led to the highest reduction in blood viscosity compared with placebo and A. sativum. In relation to the use of the two substances, G. biloba and A. sativum, dry extract of G. biloba proved to be more effective in reducing blood viscosity.
authors.affiliation: Departamento de Psicobiologia, Universidade Federal de São Paulo, Brazil. galduroz@psicobio.epm.br
authors.forename: J C F
authors.initials: JC
authors.lastname: Galduróz
authors.forename: H K
authors.initials: HK
authors.lastname: Antunes
authors.forename: R F
authors.initials: RF
authors.lastname: Santos
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000375:Aging / Q000097:blood*; D000498:Allyl Compounds / Q000494:pharmacology*; D001809:Blood Viscosity / Q000187:drug effects*; D005260:Female; D005737:Garlic; D020441:Ginkgo biloba; D006262:Health; D006801:Humans; D008297:Male; D008875:Middle Aged; D010936:Plant Extracts / Q000494:pharmacology; D012727:Sex Characteristics; D013440:Sulfides / Q000494:pharmacology*
chemical_list: D000498:Allyl Compounds; D010936:Plant Extracts; D013440:Sulfides; C038491:allyl sulfide