title: Pharmacological management of gestational diabetes: an overview.
abstract: OBJECTIVE
  To provide a review of the background literature regarding the pharmacological management of gestational diabetes.
  
  
  METHODS
  This is a literature review.
  
  
  RESULTS
  Information is available regarding the use of some, but not all, oral antidiabetes agents in pregnancy.
  
  
  CONCLUSIONS
  Available evidence supports the use of glyburide during pregnancy. Evidence is inadequate to support or refute the use of metformin, an agent that has been shown to cross the placenta and thus could be helpful or harmful to the developing fetus.
authors.affiliation: Department of Obstetrics and Gynecology, Brown Medical School, Women & Infants Hospital of Rhode Island, 101 Dudley St., Providence, RI 02905-2401, USA. dcoustan@wihri.org
authors.forename: Donald R
authors.initials: DR
authors.lastname: Coustan
mesh_terms: D016640:Diabetes, Gestational / Q000188:drug therapy*; D005260:Female; D005905:Glyburide; D006801:Humans; D007004:Hypoglycemic Agents / Q000145:classification / Q000627:therapeutic use*; D008687:Metformin / Q000009:adverse effects / Q000493:pharmacokinetics / Q000627:therapeutic use; D011247:Pregnancy
chemical_list: D007004:Hypoglycemic Agents; D008687:Metformin; D005905:Glyburide