title: Papillary and nonpapillary calcium oxalate monohydrate renal calculi: comparative study of etiologic factors.
abstract: Calcium oxalate monohydrate (COM) renal calculi can be classified into two groups: papillary and nonpapillary. In this paper, a comparative study between etiologic factors of COM papillary and nonpapillary calculi is performed. The study included 40 patients with COM renal calculi. The urine of these individuals was analyzed. Case history, lifestyle, and dietetic habits were obtained. No significant differences between urinary biochemical data of both groups were observed; 50% of COM papillary stone formers and 40% of COM nonpapillary stone formers had urolithiasis family history. A low consumption of phytate-rich products was observed for both groups. A relationship between profession with occupational exposure to cytotoxic products and COM papillary renal lithiasis was detected. The results suggest that COM papillary calculi would be associated to papillary epithelium alterations together with a crystallization inhibitors deficit, whereas COM nonpapillary calculi would be associated to the presence of heterogeneous nucleants and a crystallization inhibitors deficit.
authors.affiliation: University Hospital Son Dureta, Palma de Mallorca, Spain. 32477apa@comb.es
authors.forename: Enrique
authors.initials: E
authors.lastname: Pieras
authors.forename: Antonia
authors.initials: A
authors.lastname: Costa-Bauzá
authors.forename: Margarita
authors.initials: M
authors.lastname: Ramis
authors.forename: Felix
authors.initials: F
authors.lastname: Grases
mesh_terms: D002129:Calcium Oxalate / Q000378:metabolism* / Q000652:urine; D003460:Crystallization; D004032:Diet; D005260:Female; D006801:Humans; D007668:Kidney / Q000378:metabolism; D007669:Kidney Calculi / Q000175:diagnosis* / Q000209:etiology* / Q000648:ultrastructure / Q000652:urine; D007674:Kidney Diseases / Q000175:diagnosis / Q000209:etiology; D008019:Life Style; D008297:Male; D008855:Microscopy, Electron, Scanning; D016273:Occupational Exposure
chemical_list: D002129:Calcium Oxalate