Surgical treatment for acute symptomatic refractory status epilepticus: a case report.
A previously healthy 10-year-old boy developed generalized convulsive status epilepticus following a mild febrile illness. Prolonged video-electroencephalographic monitoring revealed frequent right hemispheric electrographic seizures that were refractory to high-dose suppressive therapy. Ictal and interictal magnetoencephalography demonstrated dipole sources projecting from the right mesial temporal region. Diffusion-weighted imaging showed restricted diffusion involving the right hippocampus. Right anterior temporal lobectomy resulted in cessation of status epilepticus. At 1-year follow-up, he attends regular school and has infrequent nocturnal seizures on chronic antiepileptic drug therapy. Surgical treatment should be considered to stop status epilepticus in selected cases of acute symptomatic refractory status epilepticus with no preexisting epilepsy or magnetic resonance imaging abnormalities and may avoid the complications associated with prolonged high-dose suppressive therapy.
Mohamed
Ismail S
IS
Division of Neurology The Hospital for Sick Children, Toronto, Ontario, Canada.
Otsubo
Hiroshi
H
Imai
Katsumi
K
Shroff
Manohar
M
Sharma
Rohit
R
Chuang
Sylvester H
SH
Donner
Elizabeth
E
Drake
James
J
Snead
O Carter
OC
D000208:Acute Disease; D038481:Anterior Temporal Lobectomy / Q000379:methods*; D002648:Child; D038524:Diffusion Magnetic Resonance Imaging; D004569:Electroencephalography; D006801:Humans; D015225:Magnetoencephalography / Q000379:methods; D008297:Male; D013226:Status Epilepticus / Q000175:diagnosis / Q000503:physiopathology / Q000601:surgery*