title: A new steroidal saponin, yuccalan, from the leaves of Yucca smalliana.
abstract: An extract of the leaves of Yucca smalliana Fern. (Agavaceae) showed potential antimicrobial activity. Employing a bioassay linked fractionation method, one of the active principles, namely yuccalan, was isolated as a new steroidal saponin. The structure of the new steroidal saponin was elucidated as 3-O-beta-D-glucopyranosyl-(1-->6)-beta-D-glucopyranosyl-(3beta, 5alpha, 6alpha, 25S)-spirostan-3,6,27-triol (1) using various spectroscopic techniques, including IR, MS, 1D and 2D 1H-NMR, and 13C-NMR. The purified yuccalan showed antifungal activities against both Rhizoctonia solani and Fusarium oxysporum.
authors.affiliation: Division of Applied Bioscience and Biotechnology, Institute of Agricultural Science and Technology, Chonnam National University, Gwangju 500-757, Korea.
authors.forename: Yu-Lan
authors.initials: YL
authors.lastname: Jin
authors.forename: Ju-Hee
authors.initials: JH
authors.lastname: Kuk
authors.forename: Kyung-Taek
authors.initials: KT
authors.lastname: Oh
authors.forename: Young-Ju
authors.initials: YJ
authors.lastname: Kim
authors.forename: Xiang-Lan
authors.initials: XL
authors.lastname: Piao
authors.forename: Ro-Dong
authors.initials: RD
authors.lastname: Park
mesh_terms: D000935:Antifungal Agents / Q000302:isolation & purification*; D009682:Magnetic Resonance Spectroscopy; D018515:Plant Leaves / Q000737:chemistry*; D012503:Saponins / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D013256:Steroids / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D027623:Yucca / Q000737:chemistry*
chemical_list: D000935:Antifungal Agents; D012503:Saponins; D013256:Steroids; C521762:yuccalan