Chronic hepatitis C virus infection is not associated with Mooren's ulcer.
OBJECTIVE
To investigate the association between chronic hepatitis C virus (HCV) infection and Mooren's ulcer.


METHODS
Eight patients from different parts of China who were diagnosed with Mooren's ulcer at the Zhongshan Ophthalmic Center, Guangzhou (China) were screened for chronic HCV infection. Mooren's ulcer was diagnosed by the typical ulcer morphology, detailed case history, physical examination, and comprehensive laboratory tests. All patients had serological screening for HCV infection.


RESULTS
Six male and two female patients were enrolled in the study. Their ages ranged from 31 to 65 years (mean 43.6+/-13.7). None of them was reported to have any clinical evidence of chronic HCV infection before enrolment and all were negative for HCV serology.


CONCLUSIONS
There was no association between chronic HCV infection and Mooren's ulcer in this limited case series study.
Wang
Q-S
QS
State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China.
Yuan
J
J
Zhou
S-Y
SY
Chen
J-Q
JQ
D000328:Adult; D000368:Aged; D003320:Corneal Ulcer / Q000097:blood / Q000821:virology*; D004797:Enzyme-Linked Immunosorbent Assay; D015828:Eye Infections, Viral / Q000150:complications*; D005260:Female; D018937:Hepatitis C Antibodies / Q000032:analysis; D019698:Hepatitis C, Chronic / Q000150:complications*; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis; D008297:Male; D008875:Middle Aged
D018937:Hepatitis C Antibodies; D007074:Immunoglobulin G