Intracranial hemorrhage sparing meningioma in an anticoagulated patient.
OBJECTIVE
The risk of intracerebral hemorrhage (ICH) in patients receiving antithrombotic therapy is well known. However, there is sparse literature regarding the risk of intracerebral hemorrhage in patients receiving warfarin, who have an intracranial meningioma.


RESULTS
We report a case of a 66-year-old man who developed multifocal ICHs in the context of supratherapeutic anticoagulation. There was sparing of the intracranial meningioma despite the development and growth of multiple intraparenchymal hemorrhages that resulted in death. We also review the literature evaluating the risk of ICH in anticoagulated patients with an intracranial meningioma.


CONCLUSIONS
The findings of this case lend further support to the gradually developing notion of relative safety of anticoagulation in patients with meningioma. They also underscore the importance of close monitoring of the INR.
Romero
José Rafael
JR
Department of Neurology, Boston University Medical Center, Boston, Massachusetts 02118, USA. joromero@bmc.org
Sakai
Osamu
O
Rice
Mary Berlik
MB
Babikian
Viken L
VL
D000368:Aged; D000925:Anticoagulants / Q000009:adverse effects; D001932:Brain Neoplasms / Q000000981:diagnostic imaging; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D006801:Humans; D020300:Intracranial Hemorrhages / Q000139:chemically induced* / Q000000981:diagnostic imaging*; D008297:Male; D008579:Meningioma / Q000000981:diagnostic imaging; D014057:Tomography, X-Ray Computed; D014859:Warfarin / Q000009:adverse effects
D000925:Anticoagulants; D014859:Warfarin