title: Artificial DNAs based on alkynyl C-nucleosides as a superior scaffold for homo- and heteroexcimer emissions.
abstract: DNA-like fluorescent oligomers composed of alkynyl beta-D-ribofuranosides bearing pyrene, perylene, and anthracene as a fluorophore were synthesized by solid-phase DNA synthesis. The fluorescent oligomers possess the defined number and order of the fluorophores. In these oligomers, the adjacent fluorophores efficiently interact with each other by hydrophobic interactions in their electronic ground states in a face-to-face fashion. The predominant excimer emissions were observed from not only the homooligomers (pyrene-pyrene and perylene-perylene systems) but also the heterooligomers (pyrene-perylene, pyrene-anthracene, and perylene-anthracene systems) in aqueous media.
authors.affiliation: Graduate School of Pharmaceutical Sciences, University of Toyama, Sugitani 2630, Toyama 930-0194, Japan.
authors.forename: Junya
authors.initials: J
authors.lastname: Chiba
authors.forename: Sakiko
authors.initials: S
authors.lastname: Takeshima
authors.forename: Kikyo
authors.initials: K
authors.lastname: Mishima
authors.forename: Hajime
authors.initials: H
authors.lastname: Maeda
authors.forename: Yasuaki
authors.initials: Y
authors.lastname: Nanai
authors.forename: Kazuhiko
authors.initials: K
authors.lastname: Mizuno
authors.forename: Masahiko
authors.initials: M
authors.lastname: Inouye
mesh_terms: D000478:Alkylation; D004247:DNA / Q000737:chemistry*; D005456:Fluorescent Dyes / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D009705:Nucleosides / Q000737:chemistry*; D009841:Oligonucleotides / Q000138:chemical synthesis* / Q000737:chemistry; D013050:Spectrometry, Fluorescence / Q000379:methods
chemical_list: D005456:Fluorescent Dyes; D009705:Nucleosides; D009841:Oligonucleotides; D004247:DNA