title: Variations in pulse oximetry plethysmographic waveform amplitude induced by passive leg raising in spontaneously breathing volunteers.
abstract: OBJECTIVE
  Noninvasive methods that could predict preload responsiveness are lacking. Our objective was to evaluate variations in pulse oximetry plethysmographic (POP) waveform amplitude (deltaPOP) induced by passive leg raising (PLR).
  
  
  METHODS
  We attached a pulse oximeter to the middle finger of 25 spontaneously breathing volunteers at several time points: baseline (ie, semirecumbent position), during PLR at 60 degrees while each subject's trunk was lowered in a supine position at 1 minute, and after putting the patient back in the semirecumbent position (5-minute rest). Heart rate, noninvasive arterial pressures (mean arterial pressure and pulse pressure), maximal POP (POPmax), minimal POP (POPmin), and deltaPOP defined as [POPmax - POPmin]/[(POPmax + POPmin)/2] were recorded using a monitor.
  
  
  RESULTS
  Heart rate, mean arterial pressure, pulse pressure, POPmax, and POPmin values were not different at baseline, during PLR at 1 minute, and after the 5-minute rest (repeated-measures analysis of variance). The median deltaPOP significantly decreased from 16% (95% confidence interval = 11%-23%) to 11% (95% confidence interval = 8%-14%) (P < .05) and then increased to 13% (95% confidence interval = 10%-21%) after the 5-minute rest (P = nonsignificant).
  
  
  CONCLUSIONS
  Passive leg raising induces a significant decrease in deltaPOP among spontaneously breathing volunteers.
authors.affiliation: Department of Emergency Medicine and Surgery, CHU Pitié-Salpêtrière, Assitance Publique-Hôpitaux de Paris, Université Pierre et Marie Curie-Paris, 75013 Paris, France.
authors.forename: Samuel
authors.initials: S
authors.lastname: Delerme
authors.forename: Robin
authors.initials: R
authors.lastname: Renault
authors.forename: Yannick
authors.initials: Y
authors.lastname: Le Manach
authors.forename: Virginie
authors.initials: V
authors.lastname: Lvovschi
authors.forename: Mouhssine
authors.initials: M
authors.lastname: Bendahou
authors.forename: Bruno
authors.initials: B
authors.lastname: Riou
authors.forename: Patrick
authors.initials: P
authors.lastname: Ray
mesh_terms: D000328:Adult; D001794:Blood Pressure; D005260:Female; D005440:Fluid Therapy; D006339:Heart Rate; D006801:Humans; D007866:Leg / Q000502:physiology; D008297:Male; D008875:Middle Aged; D009068:Movement / Q000502:physiology*; D010092:Oximetry; D010991:Plethysmography; D012119:Respiration; D012769:Shock / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy*