title: Evidence-based (S3) guidelines for the treatment of psoriasis vulgaris.
abstract: Psoriasis vulgaris is a common and often chronic inflammatory skin disease. The incidence of psoriasis in Western industrialized countries ranges from 1 to 2%. Patients afflicted with severe psoriasis vulgaris may experience a significant reduction in quality of life. Despite the large variety of treatment options available, patient surveys have revealed lack of satisfaction with the efficacy of available treatments and a high rate of non-compliance. To optimize the treatment of psoriasis in Germany, the Deutsche Dermatologische Gesellschaft (DDG) and the Berufsverband Deutscher Dermatologen (BVDD) initiated a project to develop evidence-based guidelines for the management of psoriasis. These resulting Guidelines focus on induction therapy in cases of mild, moderate, and severe plaquetype psoriasis in adults. The Guidelines include evidence-based evaluation of the efficacy of all currently available therapeutic options in Germany. In addition, they offer detailed information on how best to administer the various treatments and give information on contraindications, adverse drug reactions, and drug interactions as well as estimates of practicability and cost. The Guidelines were developed following the recommendations of the Arbeitsgemeinschaft wissenschaftlicher medizinischer Fachgesellschaften (AWMF). The therapeutic recommendations were developed by an expert group and finalized during interdisciplinary consensus conferences.
authors.affiliation: Division of Evidence Based Medicine (dEBM), Klinik für Dermatologie, Venerologie und Allergologie, Charité-Universitätsmedizin Berlin, Germany.
authors.forename: Alexander
authors.initials: A
authors.lastname: Nast
authors.forename: Ina B
authors.initials: IB
authors.lastname: Kopp
authors.forename: Matthias
authors.initials: M
authors.lastname: Augustin
authors.forename: Kirstin-Benita
authors.initials: KB
authors.lastname: Banditt
authors.forename: Wolf-Henning
authors.initials: WH
authors.lastname: Boehncke
authors.forename: Markus
authors.initials: M
authors.lastname: Follmann
authors.forename: Markus
authors.initials: M
authors.lastname: Friedrich
authors.forename: Matthias
authors.initials: M
authors.lastname: Huber
authors.forename: Christina
authors.initials: C
authors.lastname: Kahl
authors.forename: Joachim
authors.initials: J
authors.lastname: Klaus
authors.forename: Joachim
authors.initials: J
authors.lastname: Koza
authors.forename: Inga
authors.initials: I
authors.lastname: Kreiselmaier
authors.forename: Johannes
authors.initials: J
authors.lastname: Mohr
authors.forename: Ulrich
authors.initials: U
authors.lastname: Mrowietz
authors.forename: Hans-Michael
authors.initials: HM
authors.lastname: Ockenfels
authors.forename: Hans-Dieter
authors.initials: HD
authors.lastname: Orzechowski
authors.forename: Jörg
authors.initials: J
authors.lastname: Prinz
authors.forename: Kristian
authors.initials: K
authors.lastname: Reich
authors.forename: Thomas
authors.initials: T
authors.lastname: Rosenbach
authors.forename: Stefanie
authors.initials: S
authors.lastname: Rosumeck
authors.forename: Martin
authors.initials: M
authors.lastname: Schlaeger
authors.forename: Gerhard
authors.initials: G
authors.lastname: Schmid-Ott
authors.forename: Michael
authors.initials: M
authors.lastname: Sebastian
authors.forename: Volker
authors.initials: V
authors.lastname: Streit
authors.forename: Tobias
authors.initials: T
authors.lastname: Weberschock
authors.forename: Berthold
authors.initials: B
authors.lastname: Rzany
mesh_terms: D003879:Dermatologic Agents / Q000592:standards* / Q000627:therapeutic use*; D003880:Dermatology / Q000592:standards*; D005858:Germany; D019983:Guideline Adherence; D006801:Humans; D010818:Practice Patterns, Physicians' / Q000592:standards*; D011565:Psoriasis / Q000188:drug therapy*
chemical_list: D003879:Dermatologic Agents