Surgical management of brain metastases.
Metastatic brain tumors continue to increase in incidence as patients with cancer live longer. The options for management continue to evolve as well, with advances in radiation-based treatment, chemotherapy, and surgery. Although metastatic brain tumors are frequently treated without surgical intervention, there continues to be a significant role for surgery in caring for patients with these lesions. Study data have proven that surgery has a positive effect on survival and quality of life in properly selected patients. Those with a suitable age, functional status, systemic disease control, and several metastases may be suitable for surgical treatment. Advances in preoperative imaging and planning as well as intraoperative surgical adjuncts have lowered the morbidity associated with resection. With proper patient selection and operative and postoperative management, resection continues to play a significant and evolving role in the care of patients with metastatic brain tumor.
Ranasinghe
Moksha G
MG
Department of Neurosurgery, Pennsylvania State University, Hershey, Pennsylvania 17033, USA.
Sheehan
Jonas M
JM
D001932:Brain Neoplasms / Q000532:radiotherapy* / Q000556:secondary / Q000601:surgery*; D006801:Humans; D009362:Neoplasm Metastasis / Q000628:therapy*; D019635:Neurosurgical Procedures / Q000592:standards* / Q000706:statistics & numerical data; D018579:Patient Selection; D011182:Postoperative Care / Q000592:standards; D011183:Postoperative Complications / Q000209:etiology / Q000503:physiopathology; D011878:Radiotherapy / Q000592:standards* / Q000706:statistics & numerical data; D015996:Survival Rate / Q000639:trends; D016896:Treatment Outcome