title: [Sevoflurane used for induction and maintenance of anaesthesia in children].
abstract: OBJECTIVE
  To observe the effect of sevoflurane on the induction and maintenance of anaesthesia in children, and to evaluate its safety and effectiveness.
  
  
  METHODS
  Forty child patients who conformed to the selection standard were operated under anaesthesia with intubation.Without premedicant, all the patients inhaled 100% oxygen(1L/min) and sevoflurane by mask, and escalated the concentration of sevoflurane (to the maximum concentration 7%) until the lash reflex disappeared, and the maintenance concentration was controlled under 4%. All the patients were intubated, together with vecuronium 0.1mg/kg.
  
  
  RESULTS
  With little tract excretion, the achievement ratio of induction by sevoflurane was 100%, and the children tolerated well. With stable hemodynajmics,1% approximately 4.0% maintenance concentration of sevoflurane during the operation showed effective anaesthesia, no decreased heart rate or blood pressure appeared, and all the patients' body temperature was normal.
  
  
  CONCLUSIONS
  Sevoflurane for children induction can bring fewer stimuli in the respiratory tract,less cardiac vascular inhibition and palinesthesia time. Anaesthesia in children induced by sevoflurane is safe and effective.
authors.affiliation: Department of Anesthesiology, Children's Hospital of Hunan Province, Changsha 410007, China.
authors.forename: Xi-ying
authors.initials: XY
authors.lastname: Zhang
authors.forename: Qu-lian
authors.initials: QL
authors.lastname: Guo
authors.forename: Jiang-ping
authors.initials: JP
authors.lastname: Wang
authors.forename: Yi-ru
authors.initials: YR
authors.lastname: Tong
authors.forename: Xing-xing
authors.initials: XX
authors.lastname: Zhou
authors.forename: Li-dan
authors.initials: LD
authors.lastname: Jiang
mesh_terms: D000758:Anesthesia / Q000379:methods; D000769:Anesthesia, Inhalation; D018685:Anesthetics, Inhalation / Q000008:administration & dosage*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008297:Male; D008738:Methyl Ethers / Q000008:administration & dosage*; D000077149:Sevoflurane; D016896:Treatment Outcome
chemical_list: D018685:Anesthetics, Inhalation; D008738:Methyl Ethers; D000077149:Sevoflurane