title: Acute disseminated encephalomyelitis following infectious mononucleosis.
abstract: Two months following an Epstein-Barr virus infection, a 17-year-old white female presented with seizures, intermittent visual changes, and altered mental status. Magnetic resonance imaging showed white matter changes of acute disseminated encephalomyelitis with a predilection for posterior cerebral artery distributions but without radiological evidence of arteritis. Epstein-Barr virus titers and polymerase chain reaction analysis results for the virus were consistent with postinfectious acute disseminated encephalomyelitis. The symptoms and signs improved following treatment with high-dose corticosteroids and intravenous immunoglobulin. Although Epstein-Barr virus can cause acute viral encephalomyelitis, the authors report a case of acute disseminated encephalomyelitis months after acute Epstein-Barr virus infection.
authors.affiliation: Medical University of South Carolina, Charleston, SC 29425, USA. bahadori@musc.edu
authors.forename: Hamid R
authors.initials: HR
authors.lastname: Bahadori
authors.forename: Virginia C
authors.initials: VC
authors.lastname: Williams
authors.forename: Robert P
authors.initials: RP
authors.lastname: Turner
authors.forename: Zoran
authors.initials: Z
authors.lastname: Rumboldt
authors.forename: J Routt
authors.initials: JR
authors.lastname: Reigart
authors.forename: Sandra L
authors.initials: SL
authors.lastname: Fowler
authors.forename: Pamela S
authors.initials: PS
authors.lastname: Chavis
authors.forename: Bernard L
authors.initials: BL
authors.lastname: Maria
mesh_terms: D000293:Adolescent; D001921:Brain / Q000473:pathology / Q000821:virology; D004673:Encephalomyelitis, Acute Disseminated / Q000209:etiology* / Q000473:pathology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007244:Infectious Mononucleosis / Q000150:complications* / Q000473:pathology; D008279:Magnetic Resonance Imaging / Q000379:methods