Stability of multiple-locus variable-number tandem repeats in Salmonella enterica serovar typhimurium.
Variable-number tandem repeats (VNTRs) may evolve so rapidly that multiple profiles emerge during an outbreak. A total of 190 isolates from eight Salmonella enterica serovar Typhimurium outbreaks and 15 isolates from seven patients were analyzed by pulsed-field gel electrophoresis and VNTR typing. Small changes in loci were noted; otherwise, the VNTR profiles were stable during the course of the outbreaks.
Hopkins
K L
KL
Laboratory of Enteric Pathogens, Health Protection Agency Centre for Infections, London, United Kingdom. katie.hopkins@hpa.org.uk
Maguire
C
C
Best
E
E
Liebana
E
E
Threlfall
E J
EJ
D016172:DNA Fingerprinting; D004269:DNA, Bacterial / Q000235:genetics*; D004196:Disease Outbreaks; D016521:Electrophoresis, Gel, Pulsed-Field; D005838:Genotype; D006801:Humans; D011110:Polymorphism, Genetic; D012480:Salmonella Infections / Q000453:epidemiology / Q000382:microbiology*; D012486:Salmonella typhimurium / Q000235:genetics* / Q000302:isolation & purification; D020080:Tandem Repeat Sequences / Q000235:genetics*
D004269:DNA, Bacterial