Palladium-catalyzed carbonylative annulation reaction of 2-(1-alkynyl)benzenamines: selective synthesis of 3-(halomethylene)indolin-2-ones.
A novel and selective palladium-catalyzed carbonylative annulation process for the synthesis of 3-(halomethylene)indolin-2-ones was demonstrated. In the presence of PdX2 and CuX2, 3-(halomethylene)indolin-2-ones were selectively obtained from the carbonylative annulations of 2-(1-alkynyl)benzenamines with CO in moderate to good yields.
Tang
Shi
S
Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100101, China.
Yu
Quan-Fu
QF
Peng
Peng
P
Li
Jin-Heng
JH
Zhong
Ping
P
Tang
Ri-Yuan
RY
D000588:Amines / Q000737:chemistry; D001555:Benzene Derivatives / Q000737:chemistry*; D002384:Catalysis; D007211:Indoles / Q000138:chemical synthesis*; D010165:Palladium / Q000737:chemistry
D000588:Amines; D001555:Benzene Derivatives; D007211:Indoles; C456900:indolin-2-one; D010165:Palladium