Molecular basis of cytochalasan biosynthesis in fungi: gene cluster analysis and evidence for the involvement of a PKS-NRPS hybrid synthase by RNA silencing.
Schümann
Julia
J
Leibniz-Institute for Natural Product Research and Infection Biology, HKI, 07745 Jena, Germany.
Hertweck
Christian
C
D003572:Cytochalasins / Q000096:biosynthesis* / Q000737:chemistry*; D008954:Models, Biological; D015394:Molecular Structure; D005810:Multigene Family / Q000235:genetics*; D010407:Penicillium / Q000235:genetics / Q000378:metabolism*; D010453:Peptide Synthases / Q000235:genetics / Q000378:metabolism*; D048630:Polyketide Synthases / Q000235:genetics / Q000378:metabolism*; D034622:RNA Interference
D003572:Cytochalasins; D048630:Polyketide Synthases; D010453:Peptide Synthases; C104385:non-ribosomal peptide synthase