title: Detection of cognitive impairment with the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS) in adolescents with psychotic symptomatology.
abstract: Cognitive impairment has been identified in the early phase of schizophrenia spectrum disorders, and is a major contributor to disease-related disability. While screening tools assessing cognitive impairment have been validated for adult schizophrenic populations, there is a need for brief, easily administered, standardized instruments that provide clinically relevant information for adolescents. This study examines the utility of the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS) in identifying and quantifying neurocognitive impairment in adolescents with schizophrenia spectrum disorders and other serious psychiatric illnesses. 112 adolescents, including 32 healthy subjects and 80 patients, were administered the RBANS. Patients with psychotic disorders demonstrated significant impairment on the RBANS total score compared to patients with other disorders and healthy controls, but this impairment appeared somewhat less severe than is typically reported for in adult patients with schizophrenia on this measure. The RBANS appears to be sensitive in the detection of neurocognitive impairment in a psychiatric population of adolescents with psychotic symptomatology, and may therefore have utility as a clinical screening instrument and/or neurocognitive outcome measure in this population.
authors.affiliation: Department of Psychiatry, University of Lausanne, Switzerland. Laurent.Holzer@chuv.ch
authors.forename: Laurent
authors.initials: L
authors.lastname: Holzer
authors.forename: Leonie
authors.initials: L
authors.lastname: Chinet
authors.forename: Laure
authors.initials: L
authors.lastname: Jaugey
authors.forename: Bernard
authors.initials: B
authors.lastname: Plancherel
authors.forename: Caroline
authors.initials: C
authors.lastname: Sofia
authors.forename: Olivier
authors.initials: O
authors.lastname: Halfon
authors.forename: Christopher
authors.initials: C
authors.lastname: Randolph
mesh_terms: D000293:Adolescent; D000367:Age Factors; D003072:Cognition Disorders / Q000175:diagnosis*; D005260:Female; D006801:Humans; D008297:Male; D008403:Mass Screening / Q000379:methods; D009483:Neuropsychological Tests / Q000706:statistics & numerical data*; D000297:Psychology, Adolescent; D011594:Psychometrics; D011618:Psychotic Disorders / Q000175:diagnosis* / Q000523:psychology; D015203:Reproducibility of Results; D012559:Schizophrenia / Q000175:diagnosis*; D012565:Schizophrenic Psychology; D012680:Sensitivity and Specificity; D012720:Severity of Illness Index