[Distribution of hepatitis B virus genotype B subgenotype in China].
OBJECTIVE
To investigate the distribution of hepatitis B virus (HBV) genotype B subgenotype in China.


METHODS
A cohort of 511 patients with chronic HBV genotype B infection, collected from 7 centers across China, were analyzed by using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) or nucleotide sequencing.


RESULTS
For the 511 patients, only subgenotype Ba was identified and subgenotype Bj was not found.


CONCLUSIONS
In China, subgenotype Ba was the most prevalent HBV strains, while subgenotype Bj was very rarely found.
Huang
Yue-hua
YH
Department of Infectious Diseases, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
Zhou
Bin
B
Wang
Zhan-hui
ZH
Ma
Shi-wu
SW
Liang
Min-feng
MF
Hou
Jin-lin
JL
D002681:China; D004279:DNA, Viral / Q000235:genetics; D005838:Genotype; D006509:Hepatitis B / Q000821:virology*; D006515:Hepatitis B virus / Q000145:classification / Q000235:genetics* / Q000302:isolation & purification; D006801:Humans; D010802:Phylogeny; D012150:Polymorphism, Restriction Fragment Length
D004279:DNA, Viral