title: Magnetic resonance imaging as a tool for monitoring stem cell migration.
abstract: Noninvasive monitoring of stem cells is an important step in developing stem-cell-based therapies. Among several imaging techniques available, magnetic resonance imaging (MRI) provides an effective way to detect implanted stem cells in live animals. In this mini-review, we discuss the available MRI contrast agents and different cell-labeling strategies used for detection of stem cell migration in the brain. The potential effects of MRI contrast agents on stem cell viability and differentiation are also discussed.
authors.affiliation: Department of Radiology, University of Pennsylvania, Philadelphia, PA, USA.
authors.forename: S
authors.initials: S
authors.lastname: Magnitsky
authors.forename: R M
authors.initials: RM
authors.lastname: Walton
authors.forename: J H
authors.initials: JH
authors.lastname: Wolfe
authors.forename: H
authors.initials: H
authors.lastname: Poptani
mesh_terms: D000818:Animals; D002465:Cell Movement / Q000502:physiology; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008991:Monitoring, Physiologic; D013234:Stem Cells / Q000166:cytology / Q000502:physiology*