[Comparison of NucliSens HIV-1 QT and Amplicor HIV-1 monitor 1.5 in detecting HIV-1 viral load].
OBJECTIVE
To compare the results of detecting HIV-1 load by using NucliSens HIV-1 QT and Amplicor HIV-1 monitor 1.5 assays.


METHODS
Eighty-two clinical samples were collected and HIV viral load was determined with the above-mentioned two methods.


RESULTS
The number of samples in which values obtained by NucliSens HIV-1 QT and Amplicor HIV-1 monitor 1.5 differed by <0.5 log10 RNA copies/ml and in which the viral load was undetectable accounted for 88.9 percent of the measures. The correlation coefficient between the two methods was 0.956 in 56 samples of Deltalog10 VL<0.5.


CONCLUSIONS
The results of HIV-1 viral load determination with the two methods are highly comparable.
Pan
Pin-liang
PL
Chinese Center for Disease Control and Prevention, Beijing 100050, China.
Xu
Wen-yan
WY
Yao
Jun
J
Tao
Xiao-xia
XX
Pei
Li-jian
LJ
Jiang
Yan
Y
D015658:HIV Infections / Q000821:virology*; D015497:HIV-1 / Q000235:genetics* / Q000302:isolation & purification; D006801:Humans; D021141:Nucleic Acid Amplification Techniques / Q000295:instrumentation / Q000379:methods*; D012367:RNA, Viral / Q000235:genetics; D019562:Viral Load
D012367:RNA, Viral