title: Synchronous sertoli cell and serous cystadenoma tumors of the ovaries with mixed epithelial and stromal tumor of the kidney: a case report.
abstract: We present a rare case of a 68-year-old postmenopausal woman with a mobile, hard, and painless pelvic abdominal mass that was palpated to the umbilical scar. Ultrasonography demonstrated a solid mass in the upper pole of the right kidney and a predominantly solid pelvic abdominal mass. Serum testosterone was 413 ng/dL. The patient underwent laparotomy on the renal tumor, which was thought to have a probable ovarian metastasis. Bilateral ovariectomy and right nephrectomy were performed. Immunohistochemical and histopathologic assessment identified a right ovarian Sertoli cell tumor, a left ovarian serous cystadenoma, and a mixed epithelial-stromal tumor in the kidney with positive hormonal receptor. Because our patient had an ovarian neoplasm producing steroids and a kidney tumor expressing hormonal receptors, the hypothesis of possible endocrine dependence in the pathogenesis of mixed epithelial stromal tumor is reinforced.
authors.affiliation: Discipline of Gynecology and Obstetrics, Research Institute of Oncology, Federal University of Triângulo Mineiro Uberaba, Minas Gerais, Brazil.
authors.forename: Cléber Sérgio
authors.initials: CS
authors.lastname: da Silva
authors.forename: Sheila Jorge
authors.initials: SJ
authors.lastname: Adad
authors.forename: João Cristiane
authors.initials: JC
authors.lastname: Saldanha
authors.forename: Cristiane Gobbo
authors.initials: CG
authors.lastname: Cançado
authors.forename: Carlos
authors.initials: C
authors.lastname: Bachi
authors.forename: Eddie Fernando Candido
authors.initials: EF
authors.lastname: Murta
mesh_terms: D000368:Aged; D018293:Cystadenoma, Serous / Q000473:pathology*; D005260:Female; D006801:Humans; D018193:Neoplasms, Complex and Mixed / Q000473:pathology*; D009375:Neoplasms, Glandular and Epithelial / Q000473:pathology*; D010051:Ovarian Neoplasms / Q000473:pathology*; D012707:Sertoli Cell Tumor / Q000473:pathology*; D018312:Sex Cord-Gonadal Stromal Tumors / Q000473:pathology*