[Separation and purification processes of alkaloids from Lotus plumule with macroporous adsorption resin].
OBJECTIVE
To explore the optimal separation of the alkaloids from Lotus plumule by selecting appropriate macroporous adsorption resins.


METHODS
To evaluated the separating efficiency by measuring the adsorption ratio, eluting ratio and the concentration of neferine.


RESULTS
The LSA -5B macroporous adsorption resin prolided the optimal separating efficiency. The best adsorption capacity was achieved with the following conditions: the concentration of extact liquid was 0. 125 g x mL(-1) (equivalence to raw material), then the resin was washed by water to remove impurity and alkaloids were desorbed by 50% ethanol.


CONCLUSIONS
This method is simple, feasible and suitable for industry production.
Liu
Shao
S
Department of Pharmacy of Xiangya Hospital, Center South University, Hunan 410008, China. liushao999@hotmail.com
Lei
Peng
P
Li
Xin-Zhong
XZ
Chen
Ying-Hua
YH
D000327:Adsorption; D044182:Benzylisoquinolines / Q000302:isolation & purification*; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification*; D031653:Nelumbo / Q000737:chemistry*; D010946:Plants, Medicinal / Q000737:chemistry*; D012117:Resins, Synthetic / Q000737:chemistry; D012639:Seeds / Q000737:chemistry; D013678:Technology, Pharmaceutical / Q000379:methods*
D044182:Benzylisoquinolines; D004365:Drugs, Chinese Herbal; D012117:Resins, Synthetic; C057222:neferine