title: [Evaluation of the in vitro activity of meropenem against strains of extended-spectrum beta-lactamase-producing Klebsiella pneumoniae isolated in the city of Fortaleza, Ceará].
abstract: Extended-spectrum beta-lactamases are plasmid-mediated. These enzymes have the ability to hydrolyze beta-lactam antibiotics. In this study, we evaluated the in vitro activity of meropenem against ESBL-producing Klebsiella pneumoniae strains. Fourteen strains were studied. The susceptibility of these strains to meropenem was 100%.
authors.affiliation: Laboratório de Microbiologia, Departamento de Análises Clínicas e Toxicológicas, Faculdade de Farmácia, Odontologia e Enfermagem, Universidade Federal do Ceará, Fortaleza, CE. menezes@ufc.br
authors.forename: Everardo Albuquerque
authors.initials: EA
authors.lastname: Menezes
authors.forename: Kaline Medeiros
authors.initials: KM
authors.lastname: do Nascimento
authors.forename: Karla Pimenta
authors.initials: KP
authors.lastname: Soares
authors.forename: Lia Nascimento
authors.initials: LN
authors.lastname: Amorim
authors.forename: José Gadelha
authors.initials: JG
authors.lastname: Lima Neto
authors.forename: Francisco Afrânio
authors.initials: FA
authors.lastname: Cunha
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D006801:Humans; D007711:Klebsiella pneumoniae / Q000187:drug effects* / Q000201:enzymology; D000077731:Meropenem; D008826:Microbial Sensitivity Tests; D013845:Thienamycins / Q000494:pharmacology*; D001618:beta-Lactamases / Q000378:metabolism*
chemical_list: D000900:Anti-Bacterial Agents; D013845:Thienamycins; D001618:beta-Lactamases; D000077731:Meropenem