title: Gold(I)-catalyzed regioselective cyclizations of silyl ketene amides and carbamates with alkynes.
abstract: The gold(I)-catalyzed regioselective cyclizations of silyl ketene amides or carbamates with alkynes were utilized to construct cyclopentanes or dehydro-delta-lactams.
authors.affiliation: Department of Medicinal Chemistry, Merck Research Laboratories, Merck & Co. Inc., P.O. Box 2000, Rahway, NJ 07065, USA.
authors.forename: Ellen C
authors.initials: EC
authors.lastname: Minnihan
authors.forename: Steven L
authors.initials: SL
authors.lastname: Colletti
authors.forename: F Dean
authors.initials: FD
authors.lastname: Toste
authors.forename: Hong C
authors.initials: HC
authors.lastname: Shen
mesh_terms: D000480:Alkynes / Q000737:chemistry*; D002219:Carbamates / Q000737:chemistry*; D002384:Catalysis; D002625:Chemistry, Organic / Q000379:methods*; D003500:Cyclization; D005030:Ethylenes / Q000737:chemistry*; D006046:Gold / Q000737:chemistry*; D007659:Ketones / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D008956:Models, Chemical; D015394:Molecular Structure; D013237:Stereoisomerism; D013696:Temperature
chemical_list: D000480:Alkynes; D002219:Carbamates; D005030:Ethylenes; D007659:Ketones; D006046:Gold; C008223:ketene