Synovial sarcoma in children. A single centre experience.
Synovial sarcoma (SS) is a rare disease in the paediatric population, predominating in adolescents. Surgery remains the best treatment strategy for resectable cases. Adjuvant chemotherapy or radiotherapy can be used but have not proven efficacy. Metastatic disease and unsuccessful surgery are major prognostic factors. We describe four cases in children aged 7-13 years old. All of them were affected by SS of upper and lower limbs, and had satisfactory resections with different outcomes in spite of receiving diverse chemotherapy regimens. One of them is at the moment under treatment for relapse, two are disease-free and another died after metastatic disease.
Moreno Martín-Retortillo
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L
Paediatric Oncology Unit, Children's Hospital La Fe, Valencia, Spain. lucasmoreno@comv.es
Andrés Moreno
M M
MM
Cañete Nieto
A
A
Castel Sánchez
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V
D000293:Adolescent; D017024:Chemotherapy, Adjuvant; D002648:Child; D005260:Female; D006801:Humans; D035002:Lower Extremity; D008297:Male; D009367:Neoplasm Staging; D011379:Prognosis; D018714:Radiotherapy, Adjuvant; D013584:Sarcoma, Synovial / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy*; D016896:Treatment Outcome; D034941:Upper Extremity