title: [Usefulness of combined positron emission tomography and computed tomography imaging in Erdheim-Chester disease].
abstract: BACKGROUND
  Erdheim-Chester disease is a rare non-Langerhans form of histiocytosis. We report the use of combined fluorodeoxyglucose positron emission tomography and computed tomography (18F-FDG PET-CT) in this disease.
  
  
  METHODS
  Three men, aged from 55 to 74 years with confirmed Erdheim-Chester disease were included. 18F-FDG PET-CT allowed to detect visceral and vascular involvement of the disease which were overlooked with CT-scan or magnetic resonance imaging: left common carotid and ilio-femoral artery in one patient, coronary, femoral and tibia in the second, aortic, common carotid, femoral and mandibula in the remaining patient. Also, sequential 18F-FDG PET-CT was useful to appreciate treatment efficiency (decrease hyperfixation) and decide treatment modification (interferon alpha).
  
  
  CONCLUSIONS
  18F-FDG PET-CT combined imaging allows to assess the extent of involvement in Erdheim-Chester disease. 18F-FDG PET-CT may be also a useful tool in the management of Erdheim-Chester disease.
authors.affiliation: Service de médecine interne, hôpital Foch, 40, rue Worth, 92151 Suresnes cedex, France. girszyn_nicolas@yahoo.fr
authors.forename: N
authors.initials: N
authors.lastname: Girszyn
authors.forename: L
authors.initials: L
authors.lastname: Arnaud
authors.forename: D
authors.initials: D
authors.lastname: Villain
authors.forename: J-E
authors.initials: JE
authors.lastname: Kahn
authors.forename: A-M
authors.initials: AM
authors.lastname: Piette
authors.forename: O
authors.initials: O
authors.lastname: Bletry
mesh_terms: D000368:Aged; D001013:Aorta, Thoracic / Q000000981:diagnostic imaging; D031249:Erdheim-Chester Disease / Q000000981:diagnostic imaging*; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008297:Male; D049268:Positron-Emission Tomography; D019275:Radiopharmaceuticals; D014057:Tomography, X-Ray Computed
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18