title: Antitumor activities of extracts and compounds from the roots of Daphne tangutica Maxim.
abstract: The antitumor activities of the crude extracts of Daphne tangutica Maxim. (Thymelaeaceae) and some compounds were investigated in vivo for the first time. The eight tested samples exhibited inhibition in mice transplanted with sarcoma S180. Of the eight samples, two samples DTE-2 (mixture of daphnodorin E and daphnodorin F) and DTE-3 (syringin) were noted to have the most marked antitumor activity.
authors.affiliation: School of Pharmacy, Second Military Medical University, Shanghai 200433, P. R. China.
authors.forename: Wei
authors.initials: W
authors.lastname: Zhang
authors.forename: Wei-Dong
authors.initials: WD
authors.lastname: Zhang
authors.forename: Chuan
authors.initials: C
authors.lastname: Zhang
authors.forename: Run-Hui
authors.initials: RH
authors.lastname: Liu
authors.forename: Ting-Zhao
authors.initials: TZ
authors.lastname: Li
authors.forename: Peng
authors.initials: P
authors.lastname: Fu
authors.forename: Lei
authors.initials: L
authors.lastname: Shan
mesh_terms: D000818:Animals; D003374:Coumarins / Q000302:isolation & purification; D032364:Daphne / Q000737:chemistry*; D005960:Glucosides / Q000302:isolation & purification; D010666:Phenylpropionates / Q000302:isolation & purification; D010936:Plant Extracts / Q000627:therapeutic use*; D018517:Plant Roots / Q000737:chemistry*; D012510:Sarcoma 180 / Q000188:drug therapy*
chemical_list: D003374:Coumarins; D005960:Glucosides; D010666:Phenylpropionates; D010936:Plant Extracts; C035316:daphnoretin; C028305:syringin