Team work in protein processing.
MetAP substrates and their physiological roles have remained elusive. In this issue of Chemistry & Biology, Hu and colleagues [1] employ a small molecule approach to study the impact of MetAP inhibition on the molecular regulation and cellular functions of the proto-oncogene c-Src.
Hannig
Gerhard
G
Zafgen, 890 Winter Street, Suite 320, Waltham, MA 02451, USA. Gerhard.Hannig@zafgen.com
D003299:Cooperative Behavior; D011499:Protein Processing, Post-Translational; D016392:Proto-Oncogene Proteins pp60(c-src) / Q000235:genetics / Q000378:metabolism*
D016392:Proto-Oncogene Proteins pp60(c-src)