title: Spectroscopic and biological approach of Ni(II) and Cu(II) complexes of 2-pyridinecarboxaldehyde thiosemicarbazone.
abstract: Ni(II) and Cu(II) complexes having the general composition [M(L)(2)X(2)] [where L=2-pyridinecarboxaldehyde thiosemicarbazone, M=Ni(II) and Cu(II), X=Cl(-), NO(3)(-) and 1/2 SO(4)(2-)] have been synthesized. All the metal complexes were characterized by elemental analysis, molar conductance, magnetic moment, mass, IR, EPR and electronic spectral studies. The magnetic moment measurements of the complexes indicate that all the complexes are of high-spin type. On the basis of spectral studies an octahedral geometry has been assigned for Ni(II) complexes whereas tetragonal geometry for Cu(II) except [Cu(L)(2)SO(4)] which posseses five coordinated geometry. The ligand and its metal complexes were screened against phytopathogenic fungi and bacteria in vitro.
authors.affiliation: Department of Chemistry, Zakir Husain College (University of Delhi), JLN-Marg, New Delhi 110002, India.
authors.forename: Sulekh
authors.initials: S
authors.lastname: Chandra
authors.forename: Smriti
authors.initials: S
authors.lastname: Raizada
authors.forename: Monika
authors.initials: M
authors.lastname: Tyagi
authors.forename: Praveen Kumar
authors.initials: PK
authors.lastname: Sharma
mesh_terms: D001419:Bacteria / Q000187:drug effects; D001681:Biological Assay / Q000379:methods*; D003300:Copper / Q000737:chemistry* / Q000494:pharmacology; D004578:Electron Spin Resonance Spectroscopy; D004583:Electrons; D005658:Fungi / Q000187:drug effects; D008024:Ligands; D008280:Magnetics; D008826:Microbial Sensitivity Tests; D009532:Nickel / Q000737:chemistry* / Q000494:pharmacology; D011725:Pyridines / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D013055:Spectrophotometry, Infrared; D013882:Thiosemicarbazones / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology
chemical_list: D008024:Ligands; D011725:Pyridines; D013882:Thiosemicarbazones; C051439:pyridinecarboxaldehyde; D003300:Copper; D009532:Nickel