Surgery for heart failure: now something for everyone?
For the past 50 years cardiac surgery has been in a continuous state of flux. Non-transplant heart failure surgery is an expanding field at a time when medical treatment and cardiac resynchronization therapy have recognized limits. Although donor hearts can be supplied to only a tiny minority of patients who have heart failure, other surgical options may soon provide symptomatic relief for the majority. Left ventricular restoration surgery is predicated on the well-defined relationship between cardiac shape, volume, and function. The recent remarkable developments in blood pump bioengineering provide an alternative approach and a platform on which to base genetic or stem cell therapies.
Westaby
Stephen
S
Oxford Heart Centre, John Radcliffe Hospital, Headington, Oxford, UK. stephen.westaby@orh.nhs.uk <stephen.westaby@orh.nhs.uk>
D006348:Cardiac Surgical Procedures / Q000379:methods / Q000639:trends*; D006321:Heart / Q000502:physiology; D006333:Heart Failure / Q000145:classification / Q000209:etiology / Q000503:physiopathology / Q000601:surgery*; D006352:Heart Ventricles / Q000601:surgery; D006354:Heart, Artificial; D006801:Humans; D009203:Myocardial Infarction / Q000150:complications / Q000503:physiopathology; D012038:Regeneration; D016896:Treatment Outcome; D020257:Ventricular Remodeling