The role of COX-2 inhibitors in rheumatoid and osteoarthritis.
Are NSAIDs doomed to fade away, to be replaced by more targeted treatments? Or, as I have long maintained, will they survive the other current approaches to the therapy of osteoarthritis and rheumatoid arthritis, despite the recent disdain for them in some academic circles? To answer these questions, one must look at the rationale behind the development of NSAIDs.
Ehrlich
G E
GE
University of Pennsylvania, Philadelphia, PA, USA.