[Prevalence of supraesophageal manifestations in patients with gastroesophageal erosive and non-erosive reflux disease].
BACKGROUND
Respiratory, ear-nose and throat complaints, chest pain and dysphagia can be a part of clinical manifestations of gastroesophageal reflux disease. The first two are named supraesophageal manifestations of gastroesophageal reflux disease. Controversy about the prevalence of these clinical manifestations in patients with non-erosive and erosive gastroesophageal reflux disease exists.


OBJECTIVE
Evaluate the prevalence of supraesophageal manifestations in patients with erosive and non-erosive gastroesophageal reflux disease.


METHODS
Files from patients submitted to upper endoscopy, esophageal manometry and pH monitoring for the investigation of gastroesophageal reflux disease (heartburn as the chief complaint) were reviewed and respiratory and ear, nose and throat symptoms were recorded. Patients with erosive disease (grades I to III according to Savary-Miller classification) and with non-erosive disease (normal endoscopy with abnormal pH monitoring were selected. Statistical analysis included the chi-square test.


RESULTS
Two hundred and eighty patients fulfilled the inclusion criteria being 162 with erosive disease (70% with grade I esophagitis) and 118 with non-erosive disease. Overall, 88 patients had ear, nose and throat symptoms (31%), the more frequent were hoarseness and clearing and 42, respiratory manifestations (15%), being cough the more prevalent. In the ear, nose and throat symptoms group, 45 were erosive disease (28%) and 43 non-erosive disease (36.4%). As for the respiratory symptom group, 21 patients (13%) were erosive disease and 21 (18%) were non-erosive disease.


CONCLUSIONS
There was no difference in the prevalence of supraesophageal manifestations between patients with gastroesophageal erosive and non-erosive reflux disease.
Aguero
Gustavo Cálcena
GC
Universidade Gama Filho.
Lemme
Eponina M O
EM
Alvariz
Angela
A
Carvalho
Beatriz Biccas
BB
Schechter
Rosana B
RB
Abrahão
Luiz
L
D004945:Esophagoscopy; D005260:Female; D005764:Gastroesophageal Reflux / Q000150:complications*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008297:Male; D008365:Manometry; D008875:Middle Aged; D010038:Otorhinolaryngologic Diseases / Q000175:diagnosis / Q000209:etiology*; D012140:Respiratory Tract Diseases / Q000175:diagnosis / Q000209:etiology*; D012720:Severity of Illness Index