Beneficial effects of periodontal treatment on metabolic control of hypercholesterolemia.
BACKGROUND
The authors aimed to evaluate whether local periodontal therapy may influence plasma lipid levels in patients with periodontitis.


METHODS
Fifty patients (31 females and 19 males, age 36-66 yr) were randomly assigned to the treatment and control groups. Lipid profile and dental variables were measured at baseline and at the end of the study in both groups.


RESULTS
In the third month, there was a significant decrease in total and low density lipoprotein (LDL) cholesterol levels of the treatment group compared with baseline values. Also, the reduction in bleeding on probing, pocket depth, attachment loss, plaque index and gingival index were statistically significant in the treatment group.


CONCLUSIONS
The present study indicates that periodontitis causes changes in total and LDL cholesterol levels and local periodontal treatment resulted in a significant decrease in these markers. These results suggest a potential effect of periodontitis-driven systemic inflammation on lipid metabolism.
Oz
S Gul
SG
Hacettepe University Faculty of Medicine, Department of Internal Medicine, Ankara, Turkey. irem8886@yahoo.com
Fentoglu
Ozlem
O
Kilicarslan
Alpaslan
A
Guven
Gulay Sain
GS
Tanrtover
Mine Durusu
MD
Aykac
Yasar
Y
Sozen
Tumay
T
D000328:Adult; D002318:Cardiovascular Diseases / Q000097:blood / Q000517:prevention & control; D002784:Cholesterol / Q000097:blood*; D005260:Female; D006801:Humans; D006937:Hypercholesterolemia / Q000150:complications / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D010518:Periodontitis / Q000097:blood* / Q000150:complications / Q000628:therapy*; D016745:Root Planing; D014280:Triglycerides / Q000097:blood*
D014280:Triglycerides; D002784:Cholesterol