[The research of the correlation of obstructive sleep apnea-hypopnea syndrome and insulin resistance].
OBJECTIVE
To investigate whether obstructive sleep apnea-hypopnea syndrome (OSAHS) is relevant to insulin resistance (IR) and whether it is an independent factor of IR.


METHODS
Forty-eight OSAHS patients (OSAHS group) excluding obesity, high blood sugar, high blood fat and hypertension and 45 health adults without OSAHS (control group) were included in this research. The sleeping parameters such as AHI, AI, SIT90, IAT, MSaO2, LSaO2, etc., the blood pressure and abdomen circumference on both groups were measured. Six milliliter blood was drawn to measure blood sugar level and insulin level using enzyme linked immunosorbent assay in spectively.


RESULTS
There were 9 cases (18.7%) in OSAHS group whose IR > or =5, while there were 6 cases (13.3%) in the contrast group whose IR > or =5. There were no significant differences between the two groups (P > 0.05).


CONCLUSIONS
It could be concluded from this research that OSAHS is not an independent factor of IR, while obesity, high blood sugar, high blood fat, and hypertension, etc, are high relevant to IR.
Chen
Zhaoquan
Z
Department of Otorhinolaryngology, Shihua Hospital, Lanzhou, 730060, China. chenzq@lanlian.com.cn
D000328:Adult; D000368:Aged; D001786:Blood Glucose / Q000378:metabolism; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D007328:Insulin / Q000097:blood*; D007333:Insulin Resistance; D008297:Male; D008875:Middle Aged; D020181:Sleep Apnea, Obstructive / Q000097:blood* / Q000503:physiopathology
D001786:Blood Glucose; D007328:Insulin