title: [Postoperative diabetes insipidus after transsphenoidal resection of pituitary tumor].
abstract: OBJECTIVE
  To study the prevention and treatment of postoperative diabetes insipidus after removal of pituitary tumor through transsphenoidal operation, to decrease the incidence of postoperative complications and improve the treatment of pituitary tumor.
  
  
  METHODS
  The clinical data of 86 cases of transsphenoidal resection of pituitary tumor in recent 8 years were retrospectively reviewed, including 35 endoscopic operation and 51 microscopic operation. The incidence, prevention and treatment of diabetes insipidus were statistically analysed.
  
  
  RESULTS
  There were 18 cases of postoperative diabetes insipidus in total of 86 operations, including 15 acute cases, 3 delayed cases. Twelve were temporary , which recovered within 1 week. After prompt treatment, 14 recovered within 1 week, 4 recovered within 2 weeks. No persistent diabetes insipidus was found.
  
  
  CONCLUSIONS
  The key points to prevent postoperative diabetes insipidus lay in the improvement of operative skills, careful protection during operation and avoidance of unnecessary injury. In case of diabetes insipidus occurred, rational use of antidiuretics and correction of electrolyte balance were effective in the treatment of postoperative diabetes insipidus.
authors.affiliation: Otorhinolaryngology Hospita, First Affiliated Hospital of Sun Yat-sen University, Otorhinolaryngology Institute of Sun Yat-sen University, Guangzhou 510080, China.
authors.forename: Jia
authors.initials: J
authors.lastname: Tao
authors.forename: Wei-Ping
authors.initials: WP
authors.lastname: Wen
authors.forename: Wen-Bin
authors.initials: WB
authors.lastname: Lei
authors.forename: Zhong-Ping
authors.initials: ZP
authors.lastname: Chen
authors.forename: Zhen-Zhong
authors.initials: ZZ
authors.lastname: Su
authors.forename: Yong-Gao
authors.initials: YG
authors.lastname: Mu
authors.forename: Geng
authors.initials: G
authors.lastname: Xu
mesh_terms: D000328:Adult; D003919:Diabetes Insipidus / Q000209:etiology*; D004724:Endoscopy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010911:Pituitary Neoplasms / Q000601:surgery; D011183:Postoperative Complications / Q000209:etiology*; D012189:Retrospective Studies; D013101:Sphenoid Sinus / Q000601:surgery