title: Evaluation of potential health risk of arsenic-affected groundwater using indicator kriging and dose response model.
abstract: This study analyzed the potential health risk associated with the ingestion of arsenic-affected groundwater in the arseniasis-endemic Lanyang plain of northeastern Taiwan. Indicator kriging was used to estimate arsenic concentrations in groundwater. Target cancer risk (TR) and dose response functions were adopted to evaluate the potential health risk based on the estimated arsenic concentration distributions. The estimated arsenic concentrations in groundwater reveal that arsenic concentrations (>50 microg/L) in well water are high in six townships - JiaoSi, YiLan, JhungWei, WuJie, DonShan and LouDon. Highest arsenic concentrations (70.32 microg/L) are in the YiLan and the JhungWei townships. The estimated TR values at the arsenic-affected townships are ten times more than an acceptable standard (10(-6)). The largest TR values are 145.5 and 91.2 times higher than an acceptable standard for males and females, respectively. The estimated annual mortalities by arsenic-induced internal cancers occur in the YiLan township (ten cases), LouDon (five cases), WuJie (three cases), JhungWei (two cases) and DonShan (one case). The highest number of mortalities per year in the study area is 24. Residents of the six townships with high arsenic-affected groundwater should use tap water as drinking water and use groundwater only for other purpose. The well water in other townships in the Lanyang plain has no adverse effects on human health.
authors.affiliation: Department of Bioenvironmental Systems Engineering, National Taiwan University, Taipei, 106, Taiwan ROC.
authors.forename: Jin-Jing
authors.initials: JJ
authors.lastname: Lee
authors.forename: Cheng-Shin
authors.initials: CS
authors.lastname: Jang
authors.forename: Sheng-Wei
authors.initials: SW
authors.lastname: Wang
authors.forename: Chen-Wuing
authors.initials: CW
authors.lastname: Liu
mesh_terms: D001151:Arsenic / Q000633:toxicity*; D004305:Dose-Response Relationship, Drug; D004784:Environmental Monitoring; D005260:Female; D005618:Fresh Water / Q000737:chemistry; D006801:Humans; D008297:Male; D009369:Neoplasms / Q000139:chemically induced / Q000401:mortality; D018570:Risk Assessment; D013624:Taiwan; D035501:Uncertainty; D014874:Water Pollutants, Chemical / Q000633:toxicity*; D014881:Water Supply
chemical_list: D014874:Water Pollutants, Chemical; D001151:Arsenic