Periampullary carcinomas.
OBJECTIVE
The purpose of this study was to determine predictors of survival after resection for periampullary neoplasms.


METHODS
In this study, we reevaluated our 17 cases of this type tumor which we had reported as periampullar site tumors, in advanced stages with undetermined localization, in our pathology department of the Uludag University faculty of medicine.


RESULTS
Six of our cases were female, and 11 were male with a mean age of 60.6 years (range 31-77). Their main complaints were loss of weight, anorexia, jaundice and fatigue. Physical and endoscopic examination of these patients revealed periampullary mass and Whipple operations were performed on all of them. Histopathologic examinations of these tumors revealed adenocarcinoma in 15, small cell (neuroendocrin) carcinoma in two. All were in the advanced stages. Eight of them were alive and free of disease after 1.5- to 20-month follow-ups, while ten died because of disease.


CONCLUSIONS
Periampullary carcinoma is a problem with increasing clinical significance. Tumor size, tumor type and differentiation, lymph node status appears to be prognostic markers.
Filiz
Gulaydan
G
Department of Surgical Pathology, Uludag University Faculty of Medicine, Bursa, Turkey. gulaydan@uludag.edu.tr
Yerci
Omer
O
Adim
Saduman Balaban
SB
Gurel
Selim
S
Dolar
Enver
E
Memik
Faruk
F
D000328:Adult; D000368:Aged; D014670:Ampulla of Vater / Q000473:pathology / Q000601:surgery*; D002277:Carcinoma / Q000401:mortality* / Q000473:pathology / Q000601:surgery*; D004379:Duodenal Neoplasms / Q000401:mortality* / Q000473:pathology / Q000601:surgery*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D016019:Survival Analysis