title: [Effect of Xinmaitong capsule on serum matrix metalloproteinases-9, high sensitive C-reactive protein levels in patients with acute coronary syndrome].
abstract: OBJECTIVE
  To observe the influence of Xinmaitong capsule (XMT) on serum matrix metalloproteinases-9, high sensitive C-reactive protein levels in patients with acute coronary syndrome.
  
  
  METHODS
  63 cases were divided by randomized, contrastive assigned to XMT group (n = 31) and control group (n = 32). The serum levels of MMP-9 and hs-CRP before and after treatment in 12 weeks were detected.
  
  
  RESULTS
  After treatment, the serum levels of MMP-9 in control group had no changed and the levels of hs-CRP reduced. The serum levels of MMP-9 and hs-CRP in XMT group had significantly decreased. The serum levels of MMP-9 and hs-CRP had positive correlation, but had no correlation to levels of serum lipids.
  
  
  CONCLUSIONS
  XMT decreased breakdown of matrix collagen, and inflammatory reaction in the patients of ACS, which may have effect on plaque stabilization.
authors.affiliation: The First Affiliated Hospital, Sun Yat-sen UniverSity, Guangzhou 510058, China. jder@sohu.com
authors.forename: Jun
authors.initials: J
authors.lastname: Meng
authors.forename: Jian
authors.initials: J
authors.lastname: Qin
authors.forename: Yun
authors.initials: Y
authors.lastname: Ma
authors.forename: Hui-Ma
authors.initials: HM
authors.lastname: Sun
authors.forename: Chu-Fan
authors.initials: CF
authors.lastname: Luo
authors.forename: Rui-Xiang
authors.initials: RX
authors.lastname: Qiu
mesh_terms: D054058:Acute Coronary Syndrome / Q000097:blood* / Q000188:drug therapy*; D000368:Aged; D002097:C-Reactive Protein / Q000378:metabolism*; D002214:Capsules; D002784:Cholesterol / Q000097:blood; D008076:Cholesterol, HDL / Q000097:blood; D008078:Cholesterol, LDL / Q000097:blood; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D020780:Matrix Metalloproteinase 9 / Q000097:blood*; D008875:Middle Aged; D008517:Phytotherapy; D010946:Plants, Medicinal / Q000737:chemistry; D014280:Triglycerides / Q000097:blood
chemical_list: D002214:Capsules; D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal; D014280:Triglycerides; C530084:xinmaitong; D002097:C-Reactive Protein; D002784:Cholesterol; D020780:Matrix Metalloproteinase 9