title: Biology and pathogenesis of Fonsecaea pedrosoi, the major etiologic agent of chromoblastomycosis.
abstract: Fonsecaea pedrosoi is the principal etiologic agent of chromoblastomycosis, a fungal disease whose pathogenic events are poorly understood. Treatment of the disease presents poor effectiveness and serious side effects. The disease is epidemiologically important in several regions, which has stimulated studies focused on the biology and pathogenic potential of its major causative agent. In this review, we summarize the current knowledge on the biological aspects of F. pedrosoi, including cell differentiation and pathogenic mechanisms during the interaction of fungi with different hosts' elements.
authors.affiliation: Laboratório de Estudos Integrados em Bioquímica Microbiana, Departamento de Microbiologia Geral, IMPPG/Centro de Ciências da Saúde, Universidade Federal do Rio de Janeiro, Ilha do Fundão, Rio de Janeiro, RJ, Brazil. andre@micro.ufrj.br
authors.forename: André L S
authors.initials: AL
authors.lastname: Santos
authors.forename: Vanila F
authors.initials: VF
authors.lastname: Palmeira
authors.forename: Sonia
authors.initials: S
authors.lastname: Rozental
authors.forename: Lucimar F
authors.initials: LF
authors.lastname: Kneipp
authors.forename: Leonardo
authors.initials: L
authors.lastname: Nimrichter
authors.forename: Daniela S
authors.initials: DS
authors.lastname: Alviano
authors.forename: Marcio L
authors.initials: ML
authors.lastname: Rodrigues
authors.forename: Celuta S
authors.initials: CS
authors.lastname: Alviano
mesh_terms: D001203:Ascomycota / Q000737:chemistry / Q000166:cytology / Q000472:pathogenicity*; D002862:Chromoblastomycosis / Q000188:drug therapy / Q000453:epidemiology / Q000382:microbiology*; D006801:Humans