title: Third-time lung transplant using extended criteria lungs.
abstract: There is an increasing requirement for lung re-transplants (re-LTx) related to the bronchiolitis obliterans syndrome. Nevertheless, re-LTx, especially second-time re-LTx, poses the dilemma of appropriate allocation of a scarce donor lung resource versus the desire to optimize outcomes for an individual patient. Extended donors have been used to partially alleviate a scarce donor lung supply with satisfactory outcomes for primary lung transplant. However, the usefulness of the extended donors remains unknown, including donation-after-cardiac-death donors for re-LTx. This report describes a second-time re-LTx using significantly extended donor criteria lungs from a Maastricht category IV donation-after-cardiac-death donor with resultant good clinical outcomes.
authors.affiliation: Lung Transplant Service, The Alfred Hospital, Monash University, Melbourne, Victoria, Australia.
authors.forename: Takahiro
authors.initials: T
authors.lastname: Oto
authors.forename: Michael
authors.initials: M
authors.lastname: Rowland
authors.forename: Anne P
authors.initials: AP
authors.lastname: Griffiths
authors.forename: Bronwyn J
authors.initials: BJ
authors.lastname: Levvey
authors.forename: Donald S
authors.initials: DS
authors.lastname: Esmore
authors.forename: Trevor J
authors.initials: TJ
authors.lastname: Williams
authors.forename: Gregory I
authors.initials: GI
authors.lastname: Snell
mesh_terms: D000328:Adult; D000935:Antifungal Agents / Q000627:therapeutic use; D001926:Brain Death; D006801:Humans; D016040:Lung Transplantation / Q000379:methods*; D008297:Male; D009181:Mycoses / Q000517:prevention & control; D018579:Patient Selection; D011183:Postoperative Complications / Q000517:prevention & control; D011743:Pyrimidines / Q000627:therapeutic use; D012086:Reoperation; D014019:Tissue Donors / Q000706:statistics & numerical data*; D016896:Treatment Outcome; D014230:Triazoles / Q000627:therapeutic use; D065819:Voriconazole
chemical_list: D000935:Antifungal Agents; D011743:Pyrimidines; D014230:Triazoles; D065819:Voriconazole