[Diagnostic capability of PULSAR, FDT y HRT-II in glaucoma suspects].
OBJECTIVE
To determine the diagnostic capability of PULSAR-T30W, FDT-Threshold-N30 and HRT-II in glaucoma suspects.


METHODS
Forty-seven eyes from 47 referred glaucoma suspects (GS) were examined twice with each technique. Cases with TOP-WW-MD>6dB were excluded. Results were compared with those of 70 eyes from 70 normal controls (C).


RESULTS
Mean MD value using TOP-WW in the GS group (0.96dB. sd=1.7) was not significantly different from C (0.8dB. sd=1.77) (p>0.05). Disc area in GS group (2.12 mm(2). sd=0.34) was significantly greater than in C (1.97 mm2. sd=0.45) (p<0.01). For 95.7% specificity, PULSAR-sLV showed the highest sensitivity of 30.9% in individual examinations. The highest reproducible sensitivity in the two examinations was obtained using HRT-II maximum contour elevation (23.4%) and reference height (23.4%), and was 14.9% for various indices after correcting for the influence of disc area (cup area, cup/disc area ratio, maximum contour depression and mean RNFL thickness). Reproducible sensitivity of the perimetric indices was: PULSAR-MD=8.5%, PULSAR-sLV=17%, FDT-MD=6.4%, FDT-PSD=4.3%. The association of perimetric and HRT-II indices achieved high sensitivity but low diagnostic reproducibility.


CONCLUSIONS
The most effective indices were maximum contour elevation, reference height and PULSAR-sLV, although the inclusion of the optic nerve head assessment in the selection of the GS sample may have favored the HRT-II results.
González-de-la-Rosa
M
M
Servicio de Oftalmología, Hospital Universitario de Canarias, Universidad de La Laguna, Islas Canarias, España. mgdelarosa@jet.es
González-Hernández
M
M
Aguilar-Estévez
J
J
Díaz-Alemán
T
T
Armas-Plasencia
R
R
D004867:Equipment Design; D005901:Glaucoma / Q000175:diagnosis* / Q000473:pathology / Q000503:physiopathology; D006068:Gonioscopy; D006801:Humans; D018613:Microscopy, Confocal / Q000295:instrumentation / Q000379:methods; D009898:Optic Disk / Q000648:ultrastructure*; D011446:Prospective Studies; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D014054:Tomography / Q000295:instrumentation / Q000379:methods; D058609:Visual Field Tests / Q000295:instrumentation / Q000379:methods*