Trijugin-type limonoids from the leaves of Cipadessa cinerascens.
Four new trijugin-type limonoids, cipatrijugins A-D (1-4), together with the known cipadesin A (5), were isolated from the leaves of Cipadessa cinerascens, and their structures were elucidated on the basis of spectroscopic and computational methods. The ability of compounds 1-5 to inhibit the growth of the A549 and K562 tumor cell lines was evaluated.
Di
Ying-Tong
YT
State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, People's Republic of China.
He
Hong-Ping
HP
Liu
Hai-Yang
HY
Yi
Ping
P
Zhang
Zhen
Z
Ren
Yan-Li
YL
Wang
Jun-Song
JS
Sun
Qian-Yun
QY
Yang
Fu-Mei
FM
Fang
Xin
X
Li
Shun-Lin
SL
Zhu
Hua-Jie
HJ
Hao
Xiao-Jiang
XJ
D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D004354:Drug Screening Assays, Antitumor; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D006801:Humans; D036701:Limonins / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D029582:Meliaceae / Q000737:chemistry*; D015394:Molecular Structure; D018515:Plant Leaves / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*
D000972:Antineoplastic Agents, Phytogenic; D004365:Drugs, Chinese Herbal; D036701:Limonins