title: Budd-Chiari syndrome associated with hypereosinophilic syndrome; a case report.
abstract: A 27-year-old man was admitted due to abdominal fullness. He had ascites and subcutaneous nodules on his head, with liver dysfunction and eosinophilia. Abdominal imaging revealed obstruction of the hepatic veins and stenosis of the inferior vena cava. Histological diagnosis of a subcutaneous nodule revealed obstructive thrombophlebitis with eosinophils. Tyrosine kinase created by fusion of the FIP1L1 and PDGFRA genes, which is characteristic of hypereosinophilic syndrome (HES), was detected. He was diagnosed with Budd-Chiari syndrome associated with HES. Liver function tests improved after interventional therapy followed by steroid therapy. It is important to diagnose the cause of Budd-Chiari syndrome.
authors.affiliation: Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, Toon-city.
authors.forename: Ai
authors.initials: A
authors.lastname: Inoue
authors.forename: Kojiro
authors.initials: K
authors.lastname: Michitaka
authors.forename: Shuichiro
authors.initials: S
authors.lastname: Shigematsu
authors.forename: Ichiro
authors.initials: I
authors.lastname: Konishi
authors.forename: Masashi
authors.initials: M
authors.lastname: Hirooka
authors.forename: Yoichi
authors.initials: Y
authors.lastname: Hiasa
authors.forename: Hidetaka
authors.initials: H
authors.lastname: Matsui
authors.forename: Bunzo
authors.initials: B
authors.lastname: Matsuura
authors.forename: Norio
authors.initials: N
authors.lastname: Horiike
authors.forename: Takaaki
authors.initials: T
authors.lastname: Hato
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Miyaoka
authors.forename: Morikazu
authors.initials: M
authors.lastname: Onji
mesh_terms: D000328:Adult; D006502:Budd-Chiari Syndrome / Q000000981:diagnostic imaging / Q000209:etiology* / Q000628:therapy; D006801:Humans; D017681:Hypereosinophilic Syndrome / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D008297:Male; D011859:Radiography; D016896:Treatment Outcome