title: [Separation and purification processes of alkaloids from Lotus plumule with macroporous adsorption resin].
abstract: OBJECTIVE
  To explore the optimal separation of the alkaloids from Lotus plumule by selecting appropriate macroporous adsorption resins.
  
  
  METHODS
  To evaluated the separating efficiency by measuring the adsorption ratio, eluting ratio and the concentration of neferine.
  
  
  RESULTS
  The LSA -5B macroporous adsorption resin prolided the optimal separating efficiency. The best adsorption capacity was achieved with the following conditions: the concentration of extact liquid was 0. 125 g x mL(-1) (equivalence to raw material), then the resin was washed by water to remove impurity and alkaloids were desorbed by 50% ethanol.
  
  
  CONCLUSIONS
  This method is simple, feasible and suitable for industry production.
authors.affiliation: Department of Pharmacy of Xiangya Hospital, Center South University, Hunan 410008, China. liushao999@hotmail.com
authors.forename: Shao
authors.initials: S
authors.lastname: Liu
authors.forename: Peng
authors.initials: P
authors.lastname: Lei
authors.forename: Xin-Zhong
authors.initials: XZ
authors.lastname: Li
authors.forename: Ying-Hua
authors.initials: YH
authors.lastname: Chen
mesh_terms: D000327:Adsorption; D044182:Benzylisoquinolines / Q000302:isolation & purification*; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification*; D031653:Nelumbo / Q000737:chemistry*; D010946:Plants, Medicinal / Q000737:chemistry*; D012117:Resins, Synthetic / Q000737:chemistry; D012639:Seeds / Q000737:chemistry; D013678:Technology, Pharmaceutical / Q000379:methods*
chemical_list: D044182:Benzylisoquinolines; D004365:Drugs, Chinese Herbal; D012117:Resins, Synthetic; C057222:neferine