[Utilisation of gastric ring systems for pulmonary artery banding: an animal study].
OBJECTIVE
Pulmonary artery banding is often required as a first palliative procedure in infants with congenital heart disease and high pulmonary blood flow or to retrain the left ventricle. The purpose of the study was to demonstrate the safety of a gastric banding system as an adjustable pulmonary artery banding in chronic implantation.


METHODS
Five ewes underwent implantation of the banding system around the main pulmonary artery through a left thoracotomy. All had functional evaluation with progressive occlusion and opening of the device every two weeks for a total period of three months. Invasive pressure measurements in the right ventricle and aorta were carried out each time.


RESULTS
Devices could be implanted easily. Progressive occlusion and re-opening were possible in all animals during each time point. All animals survived throughout the protocol. Retrieval of the device was achieved in all animals. In one, it was challenging because of the presence of a fibrotic reaction around the device. It died because of pulmonary artery perforation before the sacrifice. At autopsy, microscopic examination showed no signs of myocardial fibrosis.


CONCLUSIONS
In animals, gastric banding system is a safe and effective implantable device to adjust pulmonary artery diameter over a prolonged period of time. This new device may be a valuable alternative to the repeated conventional pulmonary artery banding needed for ventricular retraining in humans.
Marini
D
D
APHP, Cardiologie Pédiatrique, Hôpital Necker, 75015 Paris.
Pineau
E
E
Avenet
P-L
PL
Mollet
A
A
Abadir
S
S
Bonnet
D
D
Sidi
D
D
Agnoletti
G
G
Boudjemline
Y
Y
D000818:Animals; D001011:Aorta / Q000502:physiology; D001794:Blood Pressure / Q000502:physiology; D003250:Constriction; D005260:Female; D005355:Fibrosis; D023421:Models, Animal; D019736:Prostheses and Implants; D011474:Prosthesis Design; D019919:Prosthesis Implantation; D011651:Pulmonary Artery / Q000601:surgery*; D012039:Regional Blood Flow / Q000502:physiology; D012756:Sheep; D013908:Thoracotomy; D016278:Ventricular Function, Right / Q000502:physiology; D017725:Ventricular Pressure / Q000502:physiology