title: [The impact of early alimentary nutrition on short-term prognosis after acute stroke].
abstract: OBJECTIVE
  To discuss the short-term effects of early naso-gastric nutrition after acute stroke.
  
  
  METHODS
  In a prospective non-randomized controlled design, 146 stroke patients with dysphagia were included. 75 patients in the intervention group received standard naso-gastric nutrition and 71 patients in the control group and received feeding supervised by family members. We observed the nutrition status, infective complications and mortality between the two groups for 21 days. Neurological deficit was evaluated with NIH stroke scale, Barthel index and the modified of Rankin Scale, the latter scale being calculated for 90 days.
  
  
  RESULTS
  After 21 days, the nutritional parameters (triceps skin thickness, arm muscle circumference, haemoglobin, serum albumin, and triglycerides) in the intervention group were significantly better than those in the control group. Malnutrition was observed in 27.1% of the intervention group and 48.3% of the control group (P = 0.014). The incidence of infective complications was 33.3% in the intervention group and 52.1% in the control group (P = 0.022). Mortality rate was 6.7% in the intervention group and 18.1% in the control group (P = 0.032). The score of NIH stroke scale on the 21st day in the intervention group was also significantly better than that in the control group (P = 0.008). However, the Barthel index on the 21st day and the score of the modified Rankin Scale on the 90th day of follow-up were not statistically different between the two groups.
  
  
  CONCLUSIONS
  It is suggested that standardized naso-gastric nutrition is helpful for improving short-term neurological function following acute stroke. However, improvement of Barthel index and the score of the modified Rankin Scale needs more therapeutic measures besides nutritional support.
authors.affiliation: Department of Neurology, First Municipal Hospital of Shanghai, Jiaotong University, Shanghai 200081, China. wangshaos@online.sh.cn
authors.forename: Shao-Shi
authors.initials: SS
authors.lastname: Wang
authors.forename: Tian-Heng
authors.initials: TH
authors.lastname: Zheng
authors.forename: Zhen-Li
authors.initials: ZL
authors.lastname: Chen
authors.forename: Jian-Dao
authors.initials: JD
authors.lastname: Yang
authors.forename: Xiao-Yu
authors.initials: XY
authors.lastname: Zhou
authors.forename: Chun-Feng
authors.initials: CF
authors.lastname: Liu
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002561:Cerebrovascular Disorders / Q000175:diagnosis / Q000628:therapy*; D004750:Enteral Nutrition; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D011446:Prospective Studies