[Evaluation of the in vitro activity of meropenem against strains of extended-spectrum beta-lactamase-producing Klebsiella pneumoniae isolated in the city of Fortaleza, Ceará].
Extended-spectrum beta-lactamases are plasmid-mediated. These enzymes have the ability to hydrolyze beta-lactam antibiotics. In this study, we evaluated the in vitro activity of meropenem against ESBL-producing Klebsiella pneumoniae strains. Fourteen strains were studied. The susceptibility of these strains to meropenem was 100%.
Menezes
Everardo Albuquerque
EA
Laboratório de Microbiologia, Departamento de Análises Clínicas e Toxicológicas, Faculdade de Farmácia, Odontologia e Enfermagem, Universidade Federal do Ceará, Fortaleza, CE. menezes@ufc.br
do Nascimento
Kaline Medeiros
KM
Soares
Karla Pimenta
KP
Amorim
Lia Nascimento
LN
Lima Neto
José Gadelha
JG
Cunha
Francisco Afrânio
FA
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D006801:Humans; D007711:Klebsiella pneumoniae / Q000187:drug effects* / Q000201:enzymology; D000077731:Meropenem; D008826:Microbial Sensitivity Tests; D013845:Thienamycins / Q000494:pharmacology*; D001618:beta-Lactamases / Q000378:metabolism*
D000900:Anti-Bacterial Agents; D013845:Thienamycins; D001618:beta-Lactamases; D000077731:Meropenem