title: A trisulfide-linked glycoprotein.
abstract: The first member of a novel class of chemoselective reagents, glycosyl methanedithiosulfonates, has been synthesized, identified and employed in the first examples of chemical, site-selective construction of a trisulfide-modified protein with complete conversion.
authors.affiliation: Department of Chemistry, University of Oxford, Chemistry Research Laboratory, 12 Mansfield Road, Oxford, UKOX1 3TA.
authors.forename: Gonçalo J L
authors.initials: GJ
authors.lastname: Bernardes
authors.forename: Justin P
authors.initials: JP
authors.lastname: Marston
authors.forename: Andrei S
authors.initials: AS
authors.lastname: Batsanov
authors.forename: Judith A K
authors.initials: JA
authors.lastname: Howard
authors.forename: Benjamin G
authors.initials: BG
authors.lastname: Davis
mesh_terms: D000476:Alkanesulfonates / Q000138:chemical synthesis / Q000737:chemistry*; D018360:Crystallography, X-Ray; D006023:Glycoproteins / Q000138:chemical synthesis* / Q000737:chemistry; D011487:Protein Conformation; D013440:Sulfides / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D000476:Alkanesulfonates; D006023:Glycoproteins; D013440:Sulfides