title: Growth of Foot-and-Mouth Disease Virus in Dispersed Tissue Cells: I. Methods of Production.
abstract: Methods are described for rapid and economical production of large quantities of foot-and-mouth disease virus in stationary cultures of trypsin-dispersed bovine kidney cells in a simple medium. Yields of between 10(7) and 10(8) plaque-forming units per milliliter were obtained from serum-free cultures containing approximately a million and a half viable trypsin-dispersed cells per milliliter. Some of the advantages and disadvantages of these methods of virus production are discussed.
authors.forename: R E
authors.initials: RE
authors.lastname: Patty
authors.forename: F
authors.initials: F
authors.lastname: Tozzini
authors.forename: H R
authors.initials: HR
authors.lastname: Seibold
authors.forename: J J
authors.initials: JJ
authors.lastname: Callis