Stress-induced (Takotsubo) cardiomyopathy: a transient disorder.
Once the diagnosis of Takotsubo cardiomyopathy has been made, treatment should be based upon the patient's overall clinical condition. Up to now, there has been no controlled data to guide the optimal medical regimen, but it is reasonable to treat these patients with standard medications for left ventricular systolic dysfunction during acute phase. This includes aspirin, beta-blockers, ACE-inhibitors, and diuretics as necessary for volume overload. Since this type of cardiomyopathy is a transient disorder, the appropriate duration of therapy is not known. Although the current study demonstrates that the use of beta-blockers, aspirin, ACE inhibitors and calcium channel blockers does not seem to be indicated for chronic treatment of Takotsubo cardiomyopathy, we strongly believe that we need to achieve the data which will be obtained from large scale prospective studies in the near future to assess the clinical significance of chronic medical treatment.
Celik
Turgay
T
Iyisoy
Atila
A
Yuksel
Cagdas
C
D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000627:therapeutic use; D006801:Humans; D013315:Stress, Psychological / Q000150:complications / Q000503:physiopathology / Q000628:therapy; D054549:Takotsubo Cardiomyopathy / Q000209:etiology* / Q000503:physiopathology* / Q000628:therapy; D013997:Time Factors
D000319:Adrenergic beta-Antagonists; D000806:Angiotensin-Converting Enzyme Inhibitors