title: [Typological characteristics of behavior in strains of rats bred for enhancement and absence of pendulum movements. Association with brain monoamines].
abstract: Typological characteristics of behavior were studied in rats bred for enhancement (PM+) and absence (PM-) of pendulum movements. Excitement in different test situations was manifest in PM+ rats, whereas passive defensive reactions were characteristic of PM- rats. Increased excitability of PM+ rats was expressed in their greater predisposition to audiogenic epilepsy (83% in PM+ versus 40% in PM- rats). On the contrary, PM- rats were found to be more prone to freezing (61% in PV- versus 11% in PM+). In PM+ rats, noradrenaline and serotonin contents were decreased in hypothalamus (as compared to PM- and control Wistar stain), whereas in PM- rats, serotonin content was increased in striatum, hypothalamus and midbrain as compared to control strains.
authors.forename: T A
authors.initials: TA
authors.lastname: Aleksina
authors.forename: O I
authors.initials: OI
authors.lastname: Prokudina
authors.forename: M A
authors.initials: MA
authors.lastname: Riazanova
authors.forename: T N
authors.initials: TN
authors.lastname: Ukolova
authors.forename: N N
authors.initials: NN
authors.lastname: Barykina
authors.forename: V G
authors.initials: VG
authors.lastname: Kolpakov
mesh_terms: D000161:Acoustic Stimulation; D000818:Animals; D001522:Behavior, Animal; D001921:Brain / Q000033:anatomy & histology / Q000378:metabolism*; D001947:Breeding; D020195:Epilepsy, Reflex / Q000235:genetics / Q000503:physiopathology*; D008297:Male; D009638:Norepinephrine / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains; D017208:Rats, Wistar; D012701:Serotonin / Q000378:metabolism*; D013239:Stereotyped Behavior
chemical_list: D012701:Serotonin; D009638:Norepinephrine