Investigation of meticillin-resistant Staphylococcus aureus in pigs used for research.
Meticillin-resistant Staphylococcus aureus (MRSA) was unexpectedly isolated from a pig used for streptozotocin-induced diabetes research. To investigate the possible source of the MRSA isolate, nasal swabs were obtained from the animal herd, and from animal holding rooms, and veterinary and research staff involved in the handling of the animals. Overall, four MRSA isolates were cultured from three pigs and from a clinician/scientist. Two were ST22-MRSA-IV, a human strain type associated with epidemic spread. The other two were ST398-MRSA-V, a strain type associated with pigs. Thus, care should be taken to prevent cross-transmission of MRSA.
Sergio
Darvi Michell Bufete
DMB
Department of Experimental Surgery, Singapore General Hospital, Singapore 169608, Singapore.
Koh
Tse Hsien
TH
Department of Pathology, Singapore General Hospital, Singapore 169608, Singapore.
Hsu
Li-Yang
LY
Department of Internal Medicine, Singapore General Hospital, Singapore 169608, Singapore.
Ogden
Bryan Emmett
BE
Maccine Pte Ltd, Singapore Science Park II, Singapore 117684, Singapore.|Department of Experimental Surgery, Singapore General Hospital, Singapore 169608, Singapore.
Goh
Angela L H
ALH
Department of Experimental Surgery, Singapore General Hospital, Singapore 169608, Singapore.
Chow
Pierce K H
PKH
Department of Experimental Surgery, Singapore General Hospital, Singapore 169608, Singapore.
D000822:Animal Husbandry; D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D002353:Carrier State / Q000382:microbiology; D003428:Cross Infection / Q000453:epidemiology / Q000382:microbiology / Q000662:veterinary*; D004196:Disease Outbreaks; D018562:Disease Transmission, Infectious / Q000662:veterinary*; D024881:Drug Resistance, Bacterial; D006769:Hospitals, General; D006801:Humans; D017056:Medical Laboratory Personnel; D008712:Methicillin / Q000494:pharmacology; D012307:Risk Factors; D012846:Singapore / Q000453:epidemiology; D013203:Staphylococcal Infections / Q000453:epidemiology / Q000382:microbiology / Q000635:transmission / Q000662:veterinary*; D013211:Staphylococcus aureus / Q000187:drug effects / Q000302:isolation & purification*; D013552:Swine; D013553:Swine Diseases / Q000453:epidemiology* / Q000382:microbiology; D018634:Veterinarians
D000900:Anti-Bacterial Agents; D008712:Methicillin