title: Relative susceptibility of six continuous cell lines for cultivation of Chlamydia trachomatis strains.
abstract: Since susceptibility of a cell line is an important factor for cultivation of Chlamydia trachomatis, McCoy, HeLa, BHK-21, HEp-2, Vero and A549 cell lines were tested for this characteristic. These were inoculated with 150 infection-forming units (IFU) of C. trachomatis A, B, Ba and C serovars. Growth was graded according to the number of IFUs per microscopic field (100X). A549-cell line was not susceptible to infection by any of the serovars. The growth of C. trachomatis was good to very good in McCoy and HeLa cell lines. Vero, BHK-21 and HEp-2 cell lines varied considerably in the susceptibility to infection.
authors.affiliation: L & T Microbiology Research Center, Vision Research Foundation, Sankara Nethralaya, Chennai - 600 006, Tamil Nadu, India.
authors.forename: J
authors.initials: J
authors.lastname: Malathi
authors.forename: G
authors.initials: G
authors.lastname: Shyamala
authors.forename: H N
authors.initials: HN
authors.lastname: Madhavan