[Effect of Echinacea purpurea tincture and its polysaccharide complex on the efficacy of cytostatic therapy of transferred tumors].
Experiments on C57LB/6 mice with transplanted Luis lung carcinoma showed that the officinal Echinacea purpurea preparation did not influence the efficacy of cytostatic therapy. This echinacea preparation did not change the development of metastases and even stimulated the tumor growth. In contrast, a hydrophilic polysaccharide complex isolated from echinacea increased the antitumor and antimetastatic activity of cyclophosphamide.
Razina
T G
TG
Lopatina
K A
KA
Zueva
A M
AM
Gur'ev
A M
AM
Krylova
S G
SG
Amosova
E N
EN
D000818:Animals; D000970:Antineoplastic Agents / Q000302:isolation & purification / Q000627:therapeutic use*; D018827:Carcinoma, Lewis Lung / Q000188:drug therapy*; D003520:Cyclophosphamide / Q000627:therapeutic use*; D020900:Echinacea / Q000737:chemistry*; D005260:Female; D051379:Mice; D008810:Mice, Inbred C57BL; D010936:Plant Extracts / Q000627:therapeutic use; D011134:Polysaccharides / Q000302:isolation & purification / Q000627:therapeutic use*
D000970:Antineoplastic Agents; D010936:Plant Extracts; D011134:Polysaccharides; D003520:Cyclophosphamide