[Identification of important genes by marker-trait association analysis based on hitchhiking mapping].
Most agronomic traits such as yield, quality and stress-tolerance of crops are quantitative traits. It is not easy to dissect genetic basis of these traits because they are controlled by multi-genes that are affected by environmental factors. Hitchhiking mapping offers a new method for identifying of loci controlling those traits and assessing their allelic variations. Marker-trait association analysis based on the hitchhiking effects will play an important role in dissection of complex traits. Combination of quantitative trait loci (QTL) mapping with marker-trait association analysis will facilitate dissection of complex traits, resulting in important information and markers for molecular breeding by design in crops. In this review, we presented a brief introduction of hitchhiking effects, marker-trait association analysis and practical considerations.
You
Guang-Xia
GX
Key Laboratory of Crop Germplasm & Biotechnology, MOA, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences, Beijing 100081, China. youxia72@sina.com
Zhang
Xue-Yong
XY
D002874:Chromosome Mapping / Q000379:methods*; D008957:Models, Genetic; D040641:Quantitative Trait Loci / Q000235:genetics*