title: Determination of the bactericidal activity of different calcium hydroxide presentations on a dentin model.
abstract: Calcium hydroxide placed as a temporary dressing in the root canal helps sterilize infected canals. Hycal and Roeko calcium hydroxide points are two delayed-action medications containing Ca(OH)2 recommended for root canal treatment. The purpose of this study was to test their bactericidal activity in comparison with that of C-PMCP on Streptococcus sanguins strain NCTC 7823. Artificially infected 4-mm high blocks of dentin obtained from bovine incisors were used as an experimental model (n = 192). After three days of treatment with the two antiseptics, intracanal dentin powder was collected by serial drillings and used to inoculate a culture broth. The turbidity of this broth after 24 hours showed if the bacteria were eliminated or not and was used as criterion of antiseptic efficacy. No bacterial growth was observed in the samples treated with C-PMCP. Hycal had a considerable bactericidal activity with 94% of negative cultures whereas first-generation Roeko points had no activity on the strain of S. sanguis tested.
authors.affiliation: Department of Endodontics and Restorative Dentistry, Faculty of Dental Surgery, Abidjan, Ivory Coast.
authors.forename: A
authors.initials: A
authors.lastname: Sinan
authors.forename: A J
authors.initials: AJ
authors.lastname: Adou
authors.forename: T
authors.initials: T
authors.lastname: Rochd
authors.forename: P
authors.initials: P
authors.lastname: Calas
mesh_terms: D000818:Animals; D000891:Anti-Infective Agents, Local / Q000494:pharmacology*; D002126:Calcium Hydroxide / Q000494:pharmacology*; D002164:Camphor / Q000494:pharmacology; D002417:Cattle; D002733:Chlorophenols / Q000494:pharmacology; D003804:Dentin / Q000382:microbiology*; D004338:Drug Combinations; D011897:Random Allocation; D012388:Root Canal Irrigants / Q000494:pharmacology*; D013298:Streptococcus sanguis / Q000187:drug effects*
chemical_list: D000891:Anti-Infective Agents, Local; D002733:Chlorophenols; D004338:Drug Combinations; D012388:Root Canal Irrigants; D002164:Camphor; C029804:camphorated parachlorophenol; D002126:Calcium Hydroxide