title: Case for diagnosis: 4-month-old infant with increasing cough, hemoptysis, and anemia.
abstract: A 4-month-old caucasian infant presented non-productive cough, fever associated with hemoptysis, and increasing anemia. He had mild tachypnoea; routine lab tests were normal. The thoracic HRCT scan showed a very large mass in the right lung adherent to the thorax wall, well defined and limiting the medium and upper lobe; the mass was well vascularized, and with central hypodensic areas. Fiberoptic bronchoscopy and bronchoalveolar lavage (BAL) cytology were normal. The definitive histology of the mass showed the presence of inflammatory cells admixed with fibroblasts and rare Touton giant cells in the lesion suggestive of a juvenile xanthogranuloma (JXG) of the lung.
authors.affiliation: Department of Pediatrics, Medical Hospital, University of Padua, Padua, Italy.
authors.forename: D
authors.initials: D
authors.lastname: Snijders
authors.forename: C
authors.initials: C
authors.lastname: Stenghele
authors.forename: C
authors.initials: C
authors.lastname: Monciotti
authors.forename: R Lo
authors.initials: RL
authors.lastname: Piccolo
authors.forename: R
authors.initials: R
authors.lastname: Alaggio
authors.forename: G F
authors.initials: GF
authors.lastname: Zanon
authors.forename: A
authors.initials: A
authors.lastname: Barbato
mesh_terms: D000740:Anemia / Q000209:etiology*; D001706:Biopsy; D001999:Bronchoscopy; D003371:Cough / Q000209:etiology*; D006469:Hemoptysis / Q000209:etiology*; D006801:Humans; D007223:Infant; D008171:Lung Diseases / Q000150:complications / Q000175:diagnosis*; D008297:Male; D014057:Tomography, X-Ray Computed; D014972:Xanthogranuloma, Juvenile / Q000150:complications / Q000473:pathology*