title: Shiga toxin-mediated retrograde delivery of a topoisomerase I inhibitor prodrug.
authors.affiliation: UMR 176 CNRS, Institut Curie, Centre de Recherche, 26 rue d'Ulm 75248 Paris Cedex 05, France.
authors.forename: Abdessamad
authors.initials: A
authors.lastname: El Alaoui
authors.forename: Frédéric
authors.initials: F
authors.lastname: Schmidt
authors.forename: Mohamed
authors.initials: M
authors.lastname: Amessou
authors.forename: Marianne
authors.initials: M
authors.lastname: Sarr
authors.forename: Didier
authors.initials: D
authors.lastname: Decaudin
authors.forename: Jean-Claude
authors.initials: JC
authors.lastname: Florent
authors.forename: Ludger
authors.initials: L
authors.lastname: Johannes
mesh_terms: D000818:Animals; D000972:Antineoplastic Agents, Phytogenic / Q000008:administration & dosage* / Q000494:pharmacology*; D001710:Biotin / Q000494:pharmacology; D016466:CHO Cells; D002166:Camptothecin / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000494:pharmacology; D006224:Cricetinae; D003412:Cricetulus; D004791:Enzyme Inhibitors / Q000008:administration & dosage* / Q000494:pharmacology*; D004797:Enzyme-Linked Immunosorbent Assay; D019073:HT29 Cells; D006801:Humans; D000077146:Irinotecan; D011355:Prodrugs / Q000008:administration & dosage* / Q000494:pharmacology*; D022621:Shiga Toxin / Q000494:pharmacology*; D022603:Shiga Toxins / Q000494:pharmacology; D059005:Topoisomerase II Inhibitors; D014281:Trihexosylceramides / Q000378:metabolism
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D004791:Enzyme Inhibitors; D011355:Prodrugs; D022603:Shiga Toxins; D059005:Topoisomerase II Inhibitors; D014281:Trihexosylceramides; C077239:stxB toxin; D001710:Biotin; C018549:globotriaosylceramide; D022621:Shiga Toxin; D000077146:Irinotecan; D002166:Camptothecin