title: Nematicidal metabolites produced by the endophytic fungus Geotrichum sp. AL4.
abstract: From the endophytic fungal strain Geotrichum sp. AL4, cultivated from the leaves of the neem tree (Azadirachta indica), four compounds, 1-4, were isolated from the AcOEt extract, including two new, chlorinated, epimeric 1,3-oxazinane derivatives. All compounds were assessed for their nematicidal activities against the nematodes Bursaphelenchus xylophilus and Panagrellus redivivus, and three out of the four isolates showed noticeable bioactivities.
authors.affiliation: Key Laboratory for Conservation and Utilization of Bio-Resource, Yunnan University, Kunming 650091, PR China.
authors.forename: Guo-Hong
authors.initials: GH
authors.lastname: Li
authors.forename: Ze-Fen
authors.initials: ZF
authors.lastname: Yu
authors.forename: Xuan
authors.initials: X
authors.lastname: Li
authors.forename: Xing-Biao
authors.initials: XB
authors.lastname: Wang
authors.forename: Li-Jun
authors.initials: LJ
authors.lastname: Zheng
authors.forename: Ke-Qin
authors.initials: KQ
authors.lastname: Zhang
mesh_terms: D000818:Animals; D000969:Antinematodal Agents / Q000302:isolation & purification / Q000378:metabolism* / Q000494:pharmacology; D031601:Azadirachta; D005658:Fungi / Q000378:metabolism; D005848:Geotrichum / Q000378:metabolism* / Q000502:physiology; D009348:Nematoda / Q000187:drug effects* / Q000254:growth & development; D010936:Plant Extracts / Q000302:isolation & purification / Q000378:metabolism / Q000494:pharmacology; D018515:Plant Leaves
chemical_list: D000969:Antinematodal Agents; D010936:Plant Extracts