Synthetically accessible, high-affinity phosphate anion receptors.
We report synthetically accessible receptors with protonated amines attached to a conformationally constrained backbone including amide units, and demonstrate that these receptors have high affinities (log K > 5) for phosphate anions in aqueous media at pH 7 in the presence of high concentrations of competitive chloride anions (ca. 100-fold excess).
Nelissen
Hubertus Bart F M
HB
Department of Chemistry, University of York, Heslington, York, UK YO10 5DD.
Smith
David K
DK