title: [Pédiatric haemophilus influenzae b meningitis in Dakar].
abstract: OBJECTIVE
  This study had for aim to determine the etiology of Haemophilus b pediatric meningitis.
  
  
  METHODS
  A retrospective study of 216 biologically confirmed cases was carried out during 6 years (January 1995- December 2000) on children 0 to 15 years of age, hospitalized at the Albert Royer Children Hospital Center.
  
  
  RESULTS
  Haemophilus influenzae b is the first cause of pediatric meningitis (19.7%) followed by Nesseria meningitidis (14.5%), and Streptococcus pneumoniae (13.6%). The Haemophilus influenzae b meningitis cases are distributed all year round with a peak between January and March, that is to say, during the dry and cool season. They affect children at an average age of 11.7 months, with a sex ratio of 1.1 for boys. Almost all of the patients live in the low-socio-economic areas of the Dakar suburbs (92.8%). More than 90% of the H. influenzae b isolates are sensitive to ceftriaxone (96%) chloramphenicol (93%), and to ampicillin (91%). Clinical evolution is marked by death (17.8%) and recovery with psychological, sensory, and motor sequels (19.9%).
  
  
  CONCLUSIONS
  This report should help to include the combined vaccine Antihaemophilus influenzae b in the Senegalese Broad Vaccination Program. The final aim is the reduction of morbidity and mortality of infections due to Haemophilus influenzae b.
authors.affiliation: Hôpital d'Enfants Albert-Royer de Fann Dakar, CHU de Fann, avenue Cheikh-Anta-Diop, BP 11265 Dakar, Sénégal. bccamara@yahoo.com
authors.forename: B
authors.initials: B
authors.lastname: Camara
authors.forename: P-M
authors.initials: PM
authors.lastname: Faye
authors.forename: S
authors.initials: S
authors.lastname: Diouf
authors.forename: N-R
authors.initials: NR
authors.lastname: Gueye-Diagne
authors.forename: I
authors.initials: I
authors.lastname: Diagne
authors.forename: M-F
authors.initials: MF
authors.lastname: Cissé
authors.forename: M
authors.initials: M
authors.lastname: Ba
authors.forename: H-D
authors.initials: HD
authors.lastname: Sow
authors.forename: N
authors.initials: N
authors.lastname: Kuakuvi
mesh_terms: D002648:Child; D002675:Child, Preschool; D005260:Female; D006192:Haemophilus Infections / Q000453:epidemiology* / Q000401:mortality; D006193:Haemophilus influenzae / Q000302:isolation & purification*; D006801:Humans; D007223:Infant; D008297:Male; D012675:Senegal / Q000453:epidemiology; D016019:Survival Analysis