Follow-up study of tuberculosis-exposed supermarket customers with negative tuberculin skin test results in association with positive gamma interferon release assay results.
We report a follow-up study of 29 subjects with negative tuberculin skin test (TST) results in association with positive gamma interferon release assay (IGRA) results, mainly due to responses to CFP-10 in the T-SPOT.TB assay, during a contact investigation. One year later, 12/29 subjects (41%) had converted to positive TST results in association with negative IGRA results.
Franken
Willeke P J
WP
Department of Infectious Diseases, C5-P 37, Leiden University Medical Center, P. O. Box 9600, 2300 RC Leiden, The Netherlands. w.p.j.franken@lumc.nl
Koster
Ben F P J
BF
Bossink
Ailko W J
AW
Thijsen
Steven F T
SF
Bouwman
John J M
JJ
van Dissel
Jaap T
JT
Arend
Sandra M
SM
D000328:Adult; D000368:Aged; D001426:Bacterial Proteins / Q000096:biosynthesis / Q000276:immunology; D006801:Humans; D007371:Interferon-gamma / Q000276:immunology*; D008875:Middle Aged; D014374:Tuberculin Test / Q000379:methods*; D014376:Tuberculosis / Q000175:diagnosis* / Q000276:immunology / Q000635:transmission
D001426:Bacterial Proteins; C117940:CFP-10 protein, Mycobacterium tuberculosis; D007371:Interferon-gamma