Subarachnoid hemorrhage as a complication of systemic lupus erythematosus.
BACKGROUND
Subarachnoid hemorrhage (SAH) is a rare complication of systemic lupus erythematosus (SLE).


METHODS
We made a retrospective search for patients with SLE and nontraumatic SAH from 1990 to 2006.


RESULTS
We found 10 patients with SLE and primary SAH of a total of 1,077 patients with SLE (0.93%); mean age of onset was 37.4 +/- 15.25 years and the mean duration of SLE at the onset of SAH was 98.3 +/- 50.32 months. SLEDAI and chronic damage scores were 3.67 +/- 5.20 (n = 9) and 2.90 +/- 1.45 (n = 10), respectively; 60% of patients had high Hunt-Hess scores and in only 50% of cases a saccular aneurysm was identified.


CONCLUSIONS
SAH presents in about 1% of SLE patients. Long duration of SLE and chronic damage scores might be associated risk factors.
Baizabal Carvallo
J F
JF
Department of Neurology and Psychiatry, Instituto Nacional de Ciencias Médicas y Nutrición, 'Salvador Zubirán', Mexico City, Mexico. baicarjf@hotmail.com
Cantú Brito
C
C
Estañol
B
B
García Ramos
G S
GS
D000328:Adult; D000368:Aged; D002533:Cerebral Angiography; D002908:Chronic Disease; D019992:Databases as Topic; D005260:Female; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications* / Q000453:epidemiology / Q000473:pathology / Q000628:therapy; D018810:Magnetic Resonance Angiography; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012189:Retrospective Studies; D012307:Risk Factors; D012720:Severity of Illness Index; D013345:Subarachnoid Hemorrhage / Q000453:epidemiology / Q000209:etiology* / Q000473:pathology / Q000628:therapy; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome