Gold(I)-catalyzed regioselective cyclizations of silyl ketene amides and carbamates with alkynes.
The gold(I)-catalyzed regioselective cyclizations of silyl ketene amides or carbamates with alkynes were utilized to construct cyclopentanes or dehydro-delta-lactams.
Minnihan
Ellen C
EC
Department of Medicinal Chemistry, Merck Research Laboratories, Merck & Co. Inc., P.O. Box 2000, Rahway, NJ 07065, USA.
Colletti
Steven L
SL
Toste
F Dean
FD
Shen
Hong C
HC
D000480:Alkynes / Q000737:chemistry*; D002219:Carbamates / Q000737:chemistry*; D002384:Catalysis; D002625:Chemistry, Organic / Q000379:methods*; D003500:Cyclization; D005030:Ethylenes / Q000737:chemistry*; D006046:Gold / Q000737:chemistry*; D007659:Ketones / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D008956:Models, Chemical; D015394:Molecular Structure; D013237:Stereoisomerism; D013696:Temperature
D000480:Alkynes; D002219:Carbamates; D005030:Ethylenes; D007659:Ketones; D006046:Gold; C008223:ketene