title: [Anorectal lesions in HIV-positive patients using highly active antiretroviral therapy].
abstract: Anorectal lesions are common in patients with human immunodeficiency virus (HIV). Highly active anti-retroviral therapy (HAART) has little influence on the progression of anal neoplasms. The prevalence of anorectal lesions in 88 HIV-positive patients attended at the infectious diseases service of the University Hospital of Brasília who were using HAART was studied. Sociodemographic data were collected using a pre-prepared questionnaire and then the patients underwent proctological examination. Around 71% of the patients said they practiced anal intercourse. 30.7% were using a protease inhibitor. The prevalence of anorectal lesions was 36.4%, and condyloma acuminata and anal fissure were the most frequent of these. Condyloma acuminata was the most prevalent anorectal lesion and was strongly associated with the use of lopinavir/ritonavir. Screening for anorectal lesions caused by human papillomavirus in HIV/AIDS patients who use protease inhibitors is suggested.
authors.affiliation: Núcleo de Medicina Tropical, Universidade de Brasília, Brasília, DF, Brasil. drmanuel@unb.br
authors.forename: Manuel
authors.initials: M
authors.lastname: Retamozo-Palacios
authors.forename: João Batista
authors.initials: JB
authors.lastname: de Sousa
authors.forename: João Barberino
authors.initials: JB
authors.lastname: Santos
mesh_terms: D000328:Adult; D023241:Antiretroviral Therapy, Highly Active; D001938:Brazil / Q000453:epidemiology; D005260:Female; D015658:HIV Infections / Q000188:drug therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012002:Rectal Diseases / Q000175:diagnosis / Q000453:epidemiology* / Q000209:etiology; D012307:Risk Factors; D012725:Sexual Behavior; D012959:Socioeconomic Factors