title: Achondrogenesis.
abstract: In this issue of Pediatric and Developmental Pathology, Aigner and colleagues report a detailed investigation of cartilage matrix changes in a 14-week fetus with achondrogenesis type IA. The changes reported differ from matrix alterations observed in achondrogenesis types IB or II and provide insight into the phenotypic and genotypic differences within this group of skeletal dysplasias.
authors.affiliation: Department of Laboratories, Children's Hospital and Regional Medical Center, Seattle, WA 98105, USA. raj.kapur@seattlechildrens.org
authors.forename: Raj P
authors.initials: RP
authors.lastname: Kapur
mesh_terms: D002356:Cartilage / Q000002:abnormalities*; D019902:Chondrocytes / Q000473:pathology / Q000502:physiology; D020219:Chondrogenesis / Q000235:genetics; D004252:DNA Mutational Analysis; D006801:Humans; D009154:Mutation; D010009:Osteochondrodysplasias / Q000145:classification / Q000235:genetics / Q000473:pathology*; D010013:Osteogenesis Imperfecta / Q000145:classification / Q000235:genetics / Q000473:pathology; D013796:Thanatophoric Dysplasia / Q000145:classification / Q000235:genetics / Q000473:pathology