Primary diffuse leptomeningeal gliomatosis followed with serial magnetic resonance images.
We report a case of primary diffuse leptomeningeal gliomatosis (PDLG) followed up with serial magnetic resonance images (MRI). A 45-year-old man manifested with bilateral abducens nerve palsy and meningisms. Repeated MRI revealed diffuse leptomeningeal enhancement throughout the central nervous system without intra-axial mass accompanied with the dilatation of ventricles and focally enlarged cerebral sulci. Brain biopsies showed a leptomeningeal gliomatosis. The MRI findings described here would contribute to the diagnosis of PDLG among other common diseases diffusely spreading along the leptomeningeal structures.
Ishige
Satoshi
S
Department of Neurological Surgery, Chiba University Graduate School of Medicine 1-8-1, Inohana, Chuo-ku, 260-8670 Chiba, Japan.
Iwadate
Yasuo
Y
Ishikura
Hiroshi
H
Saeki
Naokatsu
N
D017809:Fatal Outcome; D005910:Glioma / Q000378:metabolism / Q000473:pathology*; D006801:Humans; D007089:Image Enhancement; D007150:Immunohistochemistry; D008279:Magnetic Resonance Imaging; D008297:Male; D008577:Meningeal Neoplasms / Q000378:metabolism / Q000473:pathology*; D008875:Middle Aged