[Survey of current experimental studies of effects of traditional Chinese compound recipe on diabetic peripheral neuropathy].
Traditional Chinese medicine has certain effects on diabetic peripheral neuropathy and predominates in the integral medication of multi-factorial, multi-target action, et al. In this paper, the experimental studies concerning the effects of Chinese compound recipes on diabetic peripheral neuropathy in recent 6 years are reviewed in respect of the polyalcohol pathway and related metabolic disorder, the activation of protein kinase C, the formation of advanced glycation endoproducts, oxidative stress, neurotrophy factors, haemodynamics and blood vessel factors. It analyzes the existing problems and looks into the future research in this domain as well.
Wu
Qun-Li
QL
Department of Traditional Chinese Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing 100730, China.
Liang
Xiao-Chun
XC
D000818:Animals; D003929:Diabetic Neuropathies / Q000188:drug therapy* / Q000378:metabolism / Q000503:physiopathology; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification / Q000627:therapeutic use*; D004789:Enzyme Activation / Q000187:drug effects; D006439:Hemodynamics / Q000187:drug effects; D008516:Medicine, Chinese Traditional / Q000379:methods* / Q000639:trends; D009431:Neural Conduction / Q000187:drug effects*; D018384:Oxidative Stress / Q000187:drug effects; D008517:Phytotherapy / Q000379:methods / Q000639:trends; D011493:Protein Kinase C / Q000378:metabolism
D004365:Drugs, Chinese Herbal; D011493:Protein Kinase C