title: [Smoking habit and superficial bladder tumours' natural history].
abstract: OBJECTIVE
  To disclose the features of bladder cancer in current smokers at diagnosis and to study the differences in recurrence and progression between smokers and non-smokers.
  
  
  METHODS
  786 consecutive patients with bladder cancer from 1991 to 2004 were studied in a retrospective manner and characteristics of smokers tumours were compared to non smokers.
  
  
  RESULTS
  377 (48%) patients were smokers at diagnosis. There were no differences in terms of age and T stage between smokers and non smokers (t student and Chi square). We found statistical differences in tumours grade, size and multiplicity ( Chi square, p=0.046, p=0.001 and p=0.12 respectly). No differences were found between smokers and non smokers according to recurrence. (Log Rank, Breslow y Tarone-Ware N.S.). We did find differences according to progression (Log Rank p=0.03, Breslow p=0.05 y Tarone-Ware p=0.03) although it did not support multivariate study.
  
  
  CONCLUSIONS
  Currents smokers present bigger and higher grade tumors and, more frequently in a multiple fashion at diagnosis than non-smokers.
authors.affiliation: Servicio de Urología, Hospital Universitario de Getafe, Madrid. garciamediero@hotmail.com
authors.forename: J M
authors.initials: JM
authors.lastname: García Mediero
authors.forename: J
authors.initials: J
authors.lastname: Angulo Cuesta
authors.forename: M
authors.initials: M
authors.lastname: Luján Galán
authors.forename: N
authors.initials: N
authors.lastname: Rodríguez García
authors.forename: A
authors.initials: A
authors.lastname: Berenguer Sánchez
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012907:Smoking / Q000009:adverse effects*; D001749:Urinary Bladder Neoplasms / Q000209:etiology*