title: [Multiple sclerosis in children].
abstract: In 2 children, both aged 7 years, multiple sclerosis (MS) was diagnosed. In children, the initial clinical features of MS may vary greatly. The first patient presented with an acute disseminated encephalomyelitis (ADEM), and the other with a hemiparesis on the left side. In both patients, the disease was controlled by prolonged pharmacotherapy, starting with methylprednisolone and followed in the first patient by intravenous infusions of immunoglobulins and in the second patient by beta-interferon.
authors.affiliation: Erasmus MC, afd. Neurologie, MS-centrum ErasMS, s-Gravendijkwal 230, 3015 CE Rotterdam.
authors.forename: R F
authors.initials: RF
authors.lastname: Neuteboom
authors.forename: C E
authors.initials: CE
authors.lastname: Catsman-Berrevoets
authors.forename: R Q
authors.initials: RQ
authors.lastname: Hintzen
mesh_terms: D002648:Child; D003937:Diagnosis, Differential; D004673:Encephalomyelitis, Acute Disseminated / Q000209:etiology; D005260:Female; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use; D007155:Immunologic Factors / Q000627:therapeutic use; D016899:Interferon-beta / Q000627:therapeutic use; D008297:Male; D008775:Methylprednisolone / Q000627:therapeutic use; D009103:Multiple Sclerosis / Q000175:diagnosis* / Q000188:drug therapy*; D010291:Paresis / Q000209:etiology
chemical_list: D016756:Immunoglobulins, Intravenous; D007155:Immunologic Factors; D016899:Interferon-beta; D008775:Methylprednisolone