title: Parathyroid chief cell adenoma associated with massive chronic parathyroiditis in a woman with hyperparathyroidism.
abstract: We report here the case of a 43-year-old woman with hyperparathyroidism, parathyroid chief cell adenoma, and massive chronic parathyroiditis. The patient was diagnosed with breast cancer and received chemotherapy 3 years before parathyroidectomy. The question can be raised whether chemotherapeutic agents may damage parathyroid cells leading to loss of self-tolerance and autoimmune chronic parathyroiditis.
authors.affiliation: Department of Laboratory Medicine, Division of Pathology, St. Michael's Hospital, University of Toronto, 30 Bond Street, Toronto, Ontario, Canada M5B1W8. kovacsk@smh.toronto.on.ca
authors.forename: Kalman
authors.initials: K
authors.lastname: Kovacs
authors.forename: Cecil David
authors.initials: CD
authors.lastname: Bell
authors.forename: Jonathan
authors.initials: J
authors.lastname: Juco
authors.forename: Fabio
authors.initials: F
authors.lastname: Rotondo
authors.forename: Jennifer
authors.initials: J
authors.lastname: Anderson
mesh_terms: D000236:Adenoma / Q000097:blood / Q000150:complications / Q000473:pathology* / Q000601:surgery; D000328:Adult; D002118:Calcium / Q000097:blood; D002908:Chronic Disease; D006801:Humans; D006961:Hyperparathyroidism / Q000209:etiology / Q000473:pathology* / Q000601:surgery; D007249:Inflammation / Q000473:pathology / Q000601:surgery; D008297:Male; D010280:Parathyroid Glands / Q000473:pathology* / Q000601:surgery; D010281:Parathyroid Hormone / Q000097:blood; D010282:Parathyroid Neoplasms / Q000097:blood / Q000150:complications / Q000473:pathology* / Q000601:surgery; D016896:Treatment Outcome
chemical_list: D010281:Parathyroid Hormone; D002118:Calcium