title: Detection-ability evaluation of the PEImager for positron emission mammography applications.
abstract: This work is a pilot study of using a dual-head scanner in positron emission mammograph (PEM). A positron emission imager (PEImager) developed at our laboratory was used as a PEM prototype to obtain data. Dual-head projection imaging mode was used in the PEM study. An iterative algebraic reconstruction was employed to reconstruct projection data to obtain tomograms. A cylindrizal phantom filled with water was applied to simulate a breast and five hollow spheres (2 mm-10 mm diameters) filled with F-18 fluoride simulated tumors in the breast phantom. Preliminary data revealed that the locations and sizes of the hot spots in the breast phantom were determined from the reconstructed images. The ability to detect the tumor embedded in the radioactive water was evaluated. At a tumor-to-normal tissue ratio 20:1, a 3 mm tumor was detected; 5 mm and 10 mm tumors could be detected at the ratios of 10:1 and 5:1, respectively.
authors.affiliation: Institute of Nuclear Energy Research, Taiwan, ROC; Department of Nuclear Science, National Tsing-Hua University, Taiwan, ROC.
authors.forename: Meei-Lirg
authors.initials: ML
authors.lastname: Jan
authors.forename: Yu-Ching
authors.initials: YC
authors.lastname: Ni
authors.forename: Keh-Shih
authors.initials: KS
authors.lastname: Chuang
authors.forename: Hsing-Ching
authors.initials: HC
authors.lastname: Liang
authors.forename: Ying-Kai
authors.initials: YK
authors.lastname: Fu