title: Kopetdaghins A-E, sesquiterpene derivatives from the aerial parts and the roots of Dorema kopetdaghense.
abstract: Three new sesquiterpene derivatives, kopetdaghins A-C (1-3), one known prenylated coumarin (7), and two known steroid glucosides, sitosterol 3-O-glucoside and stigmasterol 3-O-glucoside, were isolated from the aerial parts of Dorema kopetdaghense. In addition, two new sesquiterpene derivatives, kopetdaghin D (4) and kopetdaghin E (5), together with kopetdaghins A-C and one known sesquiterpene coumarin (6), were isolated from the roots of the plant. The structures of these compounds were elucidated by various 1D and 2D NMR techniques as well as high-resolution positive-ion ESIMS.
authors.affiliation: Department of Pharmacognosy and Biotechnology, Faculty of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran. iransham@sina.tums.ac.ir
authors.forename: Mehrdad
authors.initials: M
authors.lastname: Iranshahi
authors.forename: Fatemeh
authors.initials: F
authors.lastname: Shaki
authors.forename: Ali
authors.initials: A
authors.lastname: Mashlab
authors.forename: Andrea
authors.initials: A
authors.lastname: Porzel
authors.forename: Ludger A
authors.initials: LA
authors.lastname: Wessjohann
mesh_terms: D019661:Apiaceae / Q000737:chemistry*; D007492:Iran; D015394:Molecular Structure; D018517:Plant Roots / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D012717:Sesquiterpenes / Q000737:chemistry / Q000302:isolation & purification*; D021241:Spectrometry, Mass, Electrospray Ionization
chemical_list: D012717:Sesquiterpenes