title: Interphase chromosome-specific multicolor banding (ICS-MCB): a new tool for analysis of interphase chromosomes in their integrity.
abstract: Biomedical research of interphase chromosomes in their integrity is hindered by technical limitations. We introduce a technology using microdissection-based engineering of DNA probes and fluorescence multicolor chromosome banding that allows studying interphase chromosome organization, numbers and rearrangements in somatic cells.
authors.affiliation: National Research Center of Mental Health, RAMS, Moscow, Russia. ivan_iourov@yahoo.com
authors.forename: Ivan Y
authors.initials: IY
authors.lastname: Iourov
authors.forename: Thomas
authors.initials: T
authors.lastname: Liehr
authors.forename: Svetlana G
authors.initials: SG
authors.lastname: Vorsanova
authors.forename: Yuri B
authors.initials: YB
authors.lastname: Yurov
mesh_terms: D002871:Chromosome Banding / Q000379:methods* / Q000639:trends; D002874:Chromosome Mapping / Q000379:methods* / Q000639:trends; D002877:Chromosomes, Human / Q000235:genetics*; D003124:Colorimetry / Q000379:methods / Q000639:trends; D015342:DNA Probes / Q000235:genetics*; D005818:Genetic Engineering / Q000379:methods*; D006801:Humans; D007399:Interphase / Q000235:genetics*; D042282:Microdissection / Q000379:methods* / Q000639:trends; D036641:Microscopy, Fluorescence, Multiphoton / Q000379:methods / Q000639:trends
chemical_list: D015342:DNA Probes