title: Successful treatment of an invasive growth hormone-secreting pituitary macroadenoma in an 8-year-old boy.
abstract: We describe an 8 year-old boy with growth acceleration due to an invasive growth hormone (GH)-secreting pituitary macroadenoma who was successfully treated with the somatostatin analogue octreotide prior to transsphenoidal microsurgery. His tumor was resected completely and the patient remains in remission.
authors.affiliation: Division of Endocrinology, Department of Pediatrics, The Ohio State University/Columbus Children's Hospital, Columbus, OH 43205, USA. bowdens@pediatrics.ohio-state.edu
authors.forename: Sasigarn A
authors.initials: SA
authors.lastname: Bowden
authors.forename: Juan F
authors.initials: JF
authors.lastname: Sotos
authors.forename: Constantine A
authors.initials: CA
authors.lastname: Stratakis
authors.forename: Robert J
authors.initials: RJ
authors.lastname: Weil
mesh_terms: D000172:Acromegaly / Q000209:etiology / Q000628:therapy; D000236:Adenoma / Q000150:complications / Q000473:pathology / Q000628:therapy*; D002648:Child; D049912:Growth Hormone-Secreting Pituitary Adenoma / Q000150:complications / Q000188:drug therapy / Q000473:pathology / Q000601:surgery / Q000628:therapy*; D006801:Humans; D008297:Male; D009361:Neoplasm Invasiveness; D015282:Octreotide / Q000627:therapeutic use*; D016896:Treatment Outcome
chemical_list: D015282:Octreotide