Predictors of target lesion revascularization and documented stent thrombosis beyond 30 days after sirolimus-eluting stent implantation: retrospective analysis in consecutive 1,070 angiographic follow-up lesions.
BACKGROUND
Outcomes after sirolimus-eluting stent (SES: Cypher) implantation remained to be elucidated in Japan.


RESULTS
Among 1,070 consecutive angiographic follow-up lesions, 99 lesions underwent target lesion revascularization (TLR) with in-stent restenosis (ISR). Retrospective estimation by multivariate analysis including 50 variables showed that the ostiums of right coronary and left circumflex arteries, hemodialysis, calcification, non-direct stenting, ISR of SES, and non-eccentric lesion were the predictors of TLR. There was no documented late stent thrombosis (LST) among 2,166 lesions and very LST (VLST) among 1,423 lesions.


CONCLUSIONS
Further revises are needed to implant SES to these predictive lesions. LST and VLST were very rare.
Mutoh
Makoto
M
Division of Cardiology, Saitama Prefecture Cardiovascular and Respiratory Center, Kumagaya, Japan. a1079081@pref.saitama.jp
Ishikawa
Tetsuya
T
Hasuda
Toshio
T
Okada
Hisayuki
H
Endo
Akira
A
Miyanaga
Satoru
S
Higashitani
Michiaki
M
Nakano
Yosuke
Y
Kubota
Takeyuki
T
Nakata
Koutarou
K
Nagoshi
Tomohisa
T
Hayashi
Mayuri
M
Sakamoto
Hiroshi
H
Oota
Masato
M
Imai
Kamon
K
Mochizuki
Seibu
S
D017023:Coronary Angiography; D005260:Female; D006083:Graft Occlusion, Vascular; D006801:Humans; D008297:Male; D009204:Myocardial Revascularization; D011237:Predictive Value of Tests; D011379:Prognosis; D012189:Retrospective Studies; D020123:Sirolimus / Q000008:administration & dosage*; D015607:Stents / Q000009:adverse effects*; D013927:Thrombosis / Q000209:etiology*
D020123:Sirolimus