title: High-resolution computed tomography of the lung in children with cystic fibrosis: technical factors.
abstract: A standard technique that controls for respiratory motion and lung volumes during imaging is necessary if high-resolution computed tomography is to be used as an outcome measure in children with cystic fibrosis. End-inspiratory and expiratory imaging allows for the detection and differentiation of early lung disease. In children ages 0-5 years, a noninvasive controlled ventilation technique is ideal, and can be used in combination with raised-volume infant pulmonary function tests. In older children, a spirometric-assisted or spirometric-triggered technique should be used. With optimal technique, radiation dose settings (kVp and mA) can be lowered to achieve a diagnostic screening high-resolution computed tomography of the lungs at a dose equivalent to that of the chest radiograph.
authors.affiliation: Department of Radiology, Columbus Children's Hospital, Ohio State University, Columbus, Ohio 43205-2696, USA. flong@chi.osu.edu
authors.forename: Frederick R
authors.initials: FR
authors.lastname: Long
mesh_terms: D002648:Child; D002675:Child, Preschool; D003550:Cystic Fibrosis / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D007223:Infant; D008168:Lung / Q000000981:diagnostic imaging*; D008297:Male; D013147:Spirometry; D014057:Tomography, X-Ray Computed