title: Measurements of non-target organ doses using MOSFET dosemeters for selected IMRT and 3D CRT radiation treatment procedures.
abstract: Many expressed concerns about the potential increase in second cancer risk from the widespread shift to intensity-modulated radiation therapy (IMRT) techniques from traditional 3-D conformal radiation treatment (3D CRT). This paper describes the study on in-phantom measurements of radiation doses in organ sites away from the primary tumour target. The measurements involved a RANDO((R)) phantom and Metal Oxide Semiconductor Field Effect Transistor dosemeters for selected 3D CRT and IMRT treatment plans. Three different treatment plans, 4-field 3D CRT, 6-field 3D CRT and 7-field IMRT for the prostate, were considered in this study. Steps to reconstruct organ doses from directly measured data were also presented. The dosemeter readings showed that the doses decrease as the distances increase for all treatment plans. At 40 cm from the prostate target, doses were <1% of the therapeutic dose. At this location, however, the IMRT plan resulted in an absorbed dose from photons, that is a factor of 3-5 higher than the 3D CRT treatment plans. This increase on absorbed dose is due to the increased exposure time for delivering the IMRT plan. The total monitor unit (MU) was 2850 for the IMRT case, while the MU was 1308 and 1260 for 6-field and 4-field 3D CRT cases, respectively. Findings from this case study involving the prostate treatments agree with those from previous studies that IMRT indeed delivers higher photon doses to locations that are away from the primary target.
authors.affiliation: Radiation Oncology, Huntsman Cancer Hospital, University of Utah, Salt Lake City, UT 84112, USA.
authors.forename: Brian
authors.initials: B
authors.lastname: Wang
authors.forename: X George
authors.initials: XG
authors.lastname: Xu
mesh_terms: D002138:Calibration; D006801:Humans; D009369:Neoplasms / Q000532:radiotherapy*; D011829:Radiation Dosage; D011832:Radiation Injuries / Q000517:prevention & control; D011874:Radiometry / Q000295:instrumentation*; D011879:Radiotherapy Dosage; D020266:Radiotherapy, Conformal; D050397:Radiotherapy, Intensity-Modulated; D012542:Scattering, Radiation