title: Successful intrauterine intracardiac transfusion in monochorionic twins affected by parvovirus B19.
abstract: OBJECTIVE
  To assess the possibility to correct for fetal anemia using an intracardiac approach in twin pregnancies affected by fetal Parvovirus B19 infection.
  
  
  METHODS
  A monochorionic twin pregnancy affected by fetal Parvovirus B19 infection and hydrops was treated using an intraabdominal approach and by intracardiac transfusions. Access to the umbilical cord was not possible.
  
  
  RESULTS
  In one fetus, hydrops resolved after intraabdominal transfusions, in the other however, hydrops was progressive. After intracardiac transfusions, both fetuses normalized.
  
  
  CONCLUSIONS
  In multiple gestation affected by anemia, intracardiac transfusion is a possible and alternative technique, if access to the cord is impossible.
authors.affiliation: Department of Obstetrics and Gynecology, University of Schleswig-Holstein, Campus Kiel, Kiel, Germany. kaisenberge@t-online.de
authors.forename: Constantin S
authors.initials: CS
authors.lastname: von Kaisenberg
authors.forename: Sandra
authors.initials: S
authors.lastname: Grebe
authors.forename: Stephanie
authors.initials: S
authors.lastname: Schleider
authors.forename: Heidi
authors.initials: H
authors.lastname: Kuhling-von Kaisenberg
authors.forename: Lars
authors.initials: L
authors.lastname: Venhoff
authors.forename: Ivo
authors.initials: I
authors.lastname: Meinhold-Heerlein
mesh_terms: D000328:Adult; D001805:Blood Transfusion, Intrauterine / Q000379:methods*; D004200:Diseases in Twins / Q000175:diagnosis / Q000628:therapy*; D005260:Female; D005315:Fetal Diseases / Q000175:diagnosis / Q000628:therapy*; D006801:Humans; D007231:Infant, Newborn; D010322:Parvoviridae Infections / Q000175:diagnosis / Q000628:therapy*; D016732:Parvovirus B19, Human / Q000302:isolation & purification; D011247:Pregnancy