title: [Vasculitic leg ulcers in primary Sjogren syndrome].
abstract: Sjögren syndrome is a rare chronic systemic autoimmune disease characterized by progressive dryness of the mucous membranes. There are many variable clinical manifestations. A 40-year-old woman presented with painful leg ulcers refractory to various therapies. She had a history of xerostomia and xerophthalmia for several years. Based on clinical, serologic and histopathologic findings, we diagnosed leg ulcers in primary Sjögren syndrome. Combing immunosuppressive therapy with phase-adapted modern wound-therapy resulted in a complete healing of the ulcers. In the case of clinically atypical leg ulcers, Sjögren syndrome should be considered as a rare differential diagnostic possibility.
authors.affiliation: Klinik und Poliklinik für Dermatologie, Venerologie und Allergologie, Universitätsklinikum Essen.
authors.forename: M
authors.initials: M
authors.lastname: Gwosdz
authors.forename: A
authors.initials: A
authors.lastname: Körber
authors.forename: U
authors.initials: U
authors.lastname: Hillen
authors.forename: J
authors.initials: J
authors.lastname: Dissemond
mesh_terms: D000287:Administration, Topical; D000328:Adult; D005260:Female; D005938:Glucocorticoids / Q000008:administration & dosage*; D006801:Humans; D007871:Leg Ulcer / Q000175:diagnosis* / Q000188:drug therapy*; D012859:Sjogren's Syndrome / Q000175:diagnosis* / Q000188:drug therapy*; D017445:Skin Diseases, Vascular / Q000175:diagnosis / Q000188:drug therapy; D016896:Treatment Outcome; D014657:Vasculitis / Q000175:diagnosis* / Q000188:drug therapy*
chemical_list: D005938:Glucocorticoids