title: Anaphylactic reaction to intralesional corticosteroid injection.
abstract: We report the case of anaphylactic reaction to carboxymethylcellulose, a dispersant in corticosteroid preparation and contrast media. Skin prick testing in this patient revealed a positive response to carboxymethylcellulose at a dilution of 1/1000. Anaphylaxis secondary to carboxymethylcellulose has previously been reported. To avoid further problems, this patient was advised to alert medical staff for the presence of allergy to carboxymethylcellulose in the event of the need for further interventional procedures. Care should be taken when giving intradermal steroids to patients with a history of anaphylaxis after contrast media.
authors.affiliation: Department of Dermatology, Beaumont Hospital, Dublin 9, Ireland. mrylaing@yahoo.co.uk
authors.forename: M E
authors.initials: ME
authors.lastname: Laing
authors.forename: B
authors.initials: B
authors.lastname: Fallis
authors.forename: G M
authors.initials: GM
authors.lastname: Murphy
mesh_terms: D000328:Adult; D000485:Allergens / Q000008:administration & dosage / Q000009:adverse effects*; D000506:Alopecia Areata / Q000188:drug therapy; D000707:Anaphylaxis / Q000139:chemically induced / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D002266:Carboxymethylcellulose Sodium / Q000008:administration & dosage / Q000009:adverse effects*; D003937:Diagnosis, Differential; D004638:Emergency Treatment; D006801:Humans; D015552:Injections, Intralesional; D008297:Male; D011310:Preservatives, Pharmaceutical / Q000009:adverse effects; D012882:Skin Tests
chemical_list: D000485:Allergens; D011310:Preservatives, Pharmaceutical; D002266:Carboxymethylcellulose Sodium