title: meso-pyrimidinyl-substituted A2B-corroles.
abstract: meso-Pyrimidinyl-substituted A2B-corroles were synthesized in good yields by condensation of 5-mesityldipyrromethane and 2-substituted 4,6-dichloropyrimidine-5-carbaldehydes. A simple reduction of the amount of Lewis acid (BF3.OEt2) resulted in the formation of A2B-corroles, which was optimized to maximize the corrole yield. Nucleophilic aromatic substitution, Suzuki, and Stille cross-coupling reactions were performed on the Cu-metalated pyrimidinylcorroles to obtain sterically encumbered triarylcorroles, while the substitution pattern at the 2-position of the pyrimidinyl substituent was altered through Liebeskind-Srogl cross-couplings.
authors.affiliation: Molecular Design and Synthesis, Department of Chemistry, Katholieke Universiteit Leuven, Celestijnenlaan 200F, 3001 Leuven, Belgium.
authors.forename: Wouter
authors.initials: W
authors.lastname: Maes
authors.forename: Thien H
authors.initials: TH
authors.lastname: Ngo
authors.forename: Jeroen
authors.initials: J
authors.lastname: Vanderhaeghen
authors.forename: Wim
authors.initials: W
authors.lastname: Dehaen