Cerebellar astrocytoma presenting with precocious puberty in a girl. Case report.
Central precocious puberty in girls is uncommon and tends to be idiopathic in most cases. In about 20 to 30% of cases there is an intracranial mass lesion. The common lesions are hypothalamic hamartomas, optic nerve gliomas, suprasellar arachnoid cysts, hydrocephalus, germinomas, and other sellar/suprasellar lesions. Central precocious puberty secondary to a cerebellar astrocytoma is extremely rare. The authors report the first case in a girl who presented with several episodes of bleeding per vaginum. There was no clinical or radiological evidence of raised intracranial pressure.
Josan
Vivek Anand
VA
Departments of Neurosurgery, Royal Children's Hospital, Melbourne, Australia. Josanv@aol.com
Timms
Craig Douglas
CD
Rickert
Christian
C
Wallace
David
D
D001254:Astrocytoma / Q000150:complications / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D002528:Cerebellar Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D002531:Cerebellum / Q000473:pathology / Q000601:surgery; D002675:Child, Preschool; D003937:Diagnosis, Differential; D004292:Dominance, Cerebral; D004958:Estradiol / Q000097:blood; D005260:Female; D012739:Gonadal Steroid Hormones / Q000097:blood; D006801:Humans; D008279:Magnetic Resonance Imaging; D008598:Menstruation / Q000502:physiology; D011629:Puberty, Precocious / Q000209:etiology*
D012739:Gonadal Steroid Hormones; D004958:Estradiol