Synthesis of the entire carbon framework of the kedarcidin chromophore aglycon.
In advanced studies directed toward the total synthesis of the kedarcidin chromophore, we have successfully achieved the late-stage installation of the nine-membered diyne ring in the presence of the highly functionalised ansamacrocyclic bridge.
Yoshimura
Fumihiko
F
Department of Chemistry, Graduate School of Science, Tohoku University, Sendai 980-8578, Japan.
Lear
Martin J
MJ
Ohashi
Isao
I
Koyama
Yasuhito
Y
Hirama
Masahiro
M
D002244:Carbon / Q000737:chemistry*; D003516:Cycloparaffins / Q000138:chemical synthesis* / Q000737:chemistry; D053281:Enediynes / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D009281:Naphthalenes / Q000138:chemical synthesis* / Q000737:chemistry
D003516:Cycloparaffins; D053281:Enediynes; D009281:Naphthalenes; C080542:kedarcidin chromophore; D002244:Carbon