title: [A case of long survival of unresected gastric cancer with excellent QOL administered by S-1 alone].
abstract: We report a case of unresectable gastric cancer, who had been treated with S-1 alone for 3 years without cancerous symptoms. The patient was a 66-year-old male. His diagnosis was advanced gastric cancer based on gastrofiberscopy. He underwent surgery on April 15, 2003. The tumor proved to be unresectable due to direct invasion of the pancreatic head, so only gastrojejunostomy was performed. On day 14 after surgery, the administration of S-1 alone was commenced at a dose of 100 mg per day in a 4-week course of medication at 2-week intervals. No side effects were noted. Moreover, his quality of life (QOL) was not disturbed, and he led an active social life throughout the course. Long survival was achieved by S-1 alone.
authors.affiliation: Dept. of Surgery, Chiba Medical Center Hospital of the National Hospital Organization.
authors.forename: Norikazu
authors.initials: N
authors.lastname: Kuroiwa
authors.forename: Yasuo
authors.initials: Y
authors.lastname: Aoki
authors.forename: Youichi
authors.initials: Y
authors.lastname: Tazawa
authors.forename: Kazuyasu
authors.initials: K
authors.lastname: Shiramatsu
authors.forename: Jun
authors.initials: J
authors.lastname: Kobayashi
authors.forename: Yuuichi
authors.initials: Y
authors.lastname: Morishima
authors.forename: Yasuyoshi
authors.initials: Y
authors.lastname: Toyoda
authors.forename: Daisuke
authors.initials: D
authors.lastname: Satomi
authors.forename: Yukio
authors.initials: Y
authors.lastname: Yoshida
authors.forename: Kaisuke
authors.initials: K
authors.lastname: Yamamoto
authors.forename: Masahiro
authors.initials: M
authors.lastname: Mori
authors.forename: Masayuki
authors.initials: M
authors.lastname: Nakano
authors.forename: Ichiro
authors.initials: I
authors.lastname: Suzuki
authors.forename: Masaru
authors.initials: M
authors.lastname: Miyazaki
mesh_terms: D000230:Adenocarcinoma / Q000188:drug therapy* / Q000473:pathology; D000368:Aged; D000964:Antimetabolites, Antineoplastic / Q000627:therapeutic use*; D004334:Drug Administration Schedule; D004338:Drug Combinations; D006801:Humans; D008297:Male; D010094:Oxonic Acid / Q000627:therapeutic use*; D011788:Quality of Life; D013274:Stomach Neoplasms / Q000188:drug therapy* / Q000473:pathology; D017741:Survivors; D005641:Tegafur / Q000627:therapeutic use*
chemical_list: D000964:Antimetabolites, Antineoplastic; D004338:Drug Combinations; C079198:S 1 (combination); D005641:Tegafur; D010094:Oxonic Acid