A trisulfide-linked glycoprotein.
The first member of a novel class of chemoselective reagents, glycosyl methanedithiosulfonates, has been synthesized, identified and employed in the first examples of chemical, site-selective construction of a trisulfide-modified protein with complete conversion.
Bernardes
Gonçalo J L
GJ
Department of Chemistry, University of Oxford, Chemistry Research Laboratory, 12 Mansfield Road, Oxford, UKOX1 3TA.
Marston
Justin P
JP
Batsanov
Andrei S
AS
Howard
Judith A K
JA
Davis
Benjamin G
BG
D000476:Alkanesulfonates / Q000138:chemical synthesis / Q000737:chemistry*; D018360:Crystallography, X-Ray; D006023:Glycoproteins / Q000138:chemical synthesis* / Q000737:chemistry; D011487:Protein Conformation; D013440:Sulfides / Q000138:chemical synthesis* / Q000737:chemistry
D000476:Alkanesulfonates; D006023:Glycoproteins; D013440:Sulfides