title: Successful treatment of metastatic androgen-independent prostate carcinoma in a transsexual patient.
abstract: The occurrence of prostate carcinoma in transsexual patients has rarely been reported. These cases present a unique challenge in that such patients are effectively receiving androgen deprivation therapy. By definition, their disease is androgen-independent prostate cancer, and the role of local therapy is undefined. We report on a male-to-female transsexual patient with metastatic prostate cancer treated successfully with combination chemotherapy after previous standard therapy failed.
authors.affiliation: The Angeles Clinic and Research Institute, Los Angeles, CA 90025, USA.
authors.forename: Tanya B
authors.initials: TB
authors.lastname: Dorff
authors.forename: Ronald L
authors.initials: RL
authors.lastname: Shazer
authors.forename: Edward M
authors.initials: EM
authors.lastname: Nepomuceno
authors.forename: Steven J
authors.initials: SJ
authors.lastname: Tucker
mesh_terms: D000230:Adenocarcinoma / Q000188:drug therapy* / Q000532:radiotherapy; D000368:Aged; D000726:Androgen Antagonists / Q000627:therapeutic use; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008297:Male; D017430:Prostate-Specific Antigen / Q000097:blood; D011471:Prostatic Neoplasms / Q000188:drug therapy* / Q000532:radiotherapy; D016879:Salvage Therapy; D014189:Transsexualism / Q000473:pathology*
chemical_list: D000726:Androgen Antagonists; D017430:Prostate-Specific Antigen