title: [Transnasal endoscopic repair of nasal-skull base defect: 69 cases].
abstract: OBJECTIVE
  To summarize the experience of transnasal endoscopic repair of nasal-skull base defect.
  
  
  METHODS
  The clinical data of 69 patients with transnasal endoscopic repair of skull base defect from January 1998 to June 2006 were analyzed retrospectively. The causes, sites of defect and the effect and key technique of transnasal endoscopic repair were investigated.
  
  
  RESULTS
  All patients were followed-up for 6 months to 11 years. The causes were mainly traumatic fracture, occupying lesions and iatrogenic trauma. The sites were mainly in ethmoid sinus and sphenoid sinus. The success rate of one attempt was 91.3% (63/69), the ultimate success rate was 95.7% (66/69).
  
  
  CONCLUSIONS
  Transnasal endoscopic repair of skull base defect may be the best approach. Debriding and raw edge of defect area and "inlay-plug" method are of key technique. The liber muscle and fascia are ideal repair material.
authors.affiliation: Department of Otorhinolaryngology Head Neck Surgery, Third Affiliated Hospital of Sun Yat-sen University, Guangzhou 510630, China. ly6x119@163.com
authors.forename: Yuan
authors.initials: Y
authors.lastname: Li
authors.forename: Xian
authors.initials: X
authors.lastname: Liu
authors.forename: Jin
authors.initials: J
authors.lastname: Ye
authors.forename: Ge-Hua
authors.initials: GH
authors.lastname: Zhang
authors.forename: Min-Qiang
authors.initials: MQ
authors.lastname: Xie
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D004724:Endoscopy; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D013517:Otorhinolaryngologic Surgical Procedures / Q000379:methods*; D012189:Retrospective Studies; D019291:Skull Base / Q000601:surgery*; D055815:Young Adult