Characterization of in vitro chlamydial cultures in low-oxygen atmospheres.
To mimic in vivo conditions during chlamydial infections, Chlamydia trachomatis serovar D and Chlamydia pneumoniae CWL029 were cultured in low-oxygen atmospheres containing 4% O(2), with parallel controls cultured in atmospheric air. Both were enriched with 5% CO(2). The results showed a dramatic increase in the growth of C. pneumoniae but not of C. trachomatis.
Juul
Nicolai
N
Institute of Medical Microbiology and Immunology, Bartholin Building, University of Aarhus, DK-8000 Aarhus C, Denmark.
Jensen
Helene
H
Hvid
Malene
M
Christiansen
Gunna
G
Birkelund
Svend
S
D000388:Air; D002692:Chlamydia trachomatis / Q000187:drug effects / Q000235:genetics / Q000254:growth & development* / Q000648:ultrastructure; D016993:Chlamydophila pneumoniae / Q000187:drug effects / Q000235:genetics / Q000254:growth & development* / Q000648:ultrastructure; D006367:HeLa Cells; D006801:Humans; D002479:Inclusion Bodies / Q000187:drug effects / Q000648:ultrastructure*; D009928:Organ Specificity; D010100:Oxygen / Q000494:pharmacology* / Q000502:physiology
D010100:Oxygen