[Studies on chemical constituents of phenols in fresh Houttuynia cordata].
OBJECTIVE
To study the aqueous constituents of Houttuynia cordata.


METHODS
Various columns including Diaion HP-20, Sephadex LH-20, ODS and silica gel were employed for the isolation and purification of compounds from H. cordata. The structures of the compounds were identified by physiochemical properties and spectral analysis.


RESULTS
Five compounds were isolated, and their structures were identified as chlorogenic methyl ester (1), (E)-4-Hydroxy-4-[3'-(beta-D-glucopyranosyloxy) butylidene]-3, 5, 5-trimethyl-2-cyclohexen-1-one (2), 2-(3, 4-dihydroxyphenyl) ethyl-beta-D-glucopyranoside (3), p-hydroxyphenethyl-beta-D-glucoside (4), 4-(beta-D-glucopyranosyloxy)-3-hydroxy-Benzoic acid (5).


CONCLUSIONS
All compounds were isolated from this plant for the first time.
Meng
Jiang
J
GuangDong Pharmaceutical University, Guangzhou 510000, China. jiangmeng666@126.com
Dong
Xiao-Ping
XP
Zhou
Yi-Sheng
YS
Jiang
Zhi-Hong
ZH
Leung
Sze-Yin Kelvin
SY
Zhao
Zhong-Zhen
ZZ
D002726:Chlorogenic Acid / Q000031:analogs & derivatives* / Q000737:chemistry / Q000302:isolation & purification; D002850:Chromatography, Gel; D003512:Cyclohexanones / Q000737:chemistry / Q000302:isolation & purification*; D005960:Glucosides / Q000737:chemistry / Q000302:isolation & purification*; D052859:Houttuynia / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D010636:Phenols / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D021241:Spectrometry, Mass, Electrospray Ionization
C503180:2-(3,4-dihydroxyphenyl)ethyl-O-glucopyranoside; C530448:4-hydroxy-4-(3'-glucopyranosyloxybutylidene)-3,5,5-trimethyl-2-cyclohexen-1-one; D003512:Cyclohexanones; D005960:Glucosides; D010636:Phenols; D002726:Chlorogenic Acid; C417238:methyl chlorogenate