Budd-Chiari syndrome associated with hypereosinophilic syndrome; a case report.
A 27-year-old man was admitted due to abdominal fullness. He had ascites and subcutaneous nodules on his head, with liver dysfunction and eosinophilia. Abdominal imaging revealed obstruction of the hepatic veins and stenosis of the inferior vena cava. Histological diagnosis of a subcutaneous nodule revealed obstructive thrombophlebitis with eosinophils. Tyrosine kinase created by fusion of the FIP1L1 and PDGFRA genes, which is characteristic of hypereosinophilic syndrome (HES), was detected. He was diagnosed with Budd-Chiari syndrome associated with HES. Liver function tests improved after interventional therapy followed by steroid therapy. It is important to diagnose the cause of Budd-Chiari syndrome.
Inoue
Ai
A
Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, Toon-city.
Michitaka
Kojiro
K
Shigematsu
Shuichiro
S
Konishi
Ichiro
I
Hirooka
Masashi
M
Hiasa
Yoichi
Y
Matsui
Hidetaka
H
Matsuura
Bunzo
B
Horiike
Norio
N
Hato
Takaaki
T
Miyaoka
Hiroaki
H
Onji
Morikazu
M
D000328:Adult; D006502:Budd-Chiari Syndrome / Q000000981:diagnostic imaging / Q000209:etiology* / Q000628:therapy; D006801:Humans; D017681:Hypereosinophilic Syndrome / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D008297:Male; D011859:Radiography; D016896:Treatment Outcome