[Observation on the change of anti-S. japonicum antibody level in population migrated from outside embankment to new town].
OBJECTIVE
To detect the change of the anti-S. japonicum antibody level after people migrated from outside embankment to newly established town.


METHODS
Three pilot spots were established for the investigation: one spot that both inhabitancy and cultivation disuse (A), one spot that only inhabitancy disuse but farming continued (B) and the third one served as control (C). DIGFA and ELISA were used to detect the antibody level in the populations from 2002 to 2005.


RESULTS
The positive rate of anti-S. japonicum antibody declined significantly from 6.63% to 3.52% by DIGFA and from 7.26% to 3.71% by ELISA at spot A (chi2=5.2625, P<0.05; chi2=6.3296, P<0.05, respectively). There was no significant difference on the positive rate of antibody in spots B and C. The average A450 value of ELISA in the three spots was statistically analyzed by One-Way ANOVA. It was only in spot B that the average A450 value declined from 0.182 in 2003 to 0.147 in 2005 (P<0.01).


CONCLUSIONS
The anti-S. japonicum antibody level in human population has decreased at certain degree after they migrated from outside embankment to new town.
Wen
Li-Yong
LY
Institute of Parasitic Diseases, Zhejiang Academy of Medical Sciences, WHO Collaborating Center for Research on Helminthiasis, Hangzhou 310013, China. wenliyonghz@hotmail.com
Lu
Shao-Hong
SH
Chen
Jun-Hu
JH
Zhang
Jian-Feng
JF
Yu
Li-Ling
LL
Ding
Jian-Zu
JZ
Yan
Xiao-Lan
XL
Shen
Li-Ying
LY
Zheng
Wei
W
Gao
Lu-Lu
LL
Wang
Tian-Ping
TP
Zhang
Shi-Qing
SQ
Chen
Geng-Xin
GX
Ye
Yun
Y
Zhou
Xiao-Nong
XN
Zheng
Jiang
J
D000818:Animals; D000909:Antibodies, Helminth / Q000097:blood*; D000947:Antigens, Helminth / Q000097:blood; D002681:China / Q000453:epidemiology; D004797:Enzyme-Linked Immunosorbent Assay; D006801:Humans; D011157:Population Dynamics; D012549:Schistosoma japonicum / Q000276:immunology*; D012554:Schistosomiasis japonica / Q000453:epidemiology* / Q000469:parasitology / Q000517:prevention & control; D014171:Transients and Migrants
D000909:Antibodies, Helminth; D000947:Antigens, Helminth