Four cases of nafcillin-associated acute interstitial nephritis in one institution.
BACKGROUND
Over the course of 1 year, four patients in a single institution developed acute kidney injury most likely secondary to nafcillin-associated acute interstitial nephritis, indicating that this complication might not be as rare as is commonly believed. The main case presented here is that of a 73-year-old man with a history of chronic low back pain who presented with worsening back pain, as well as nausea, vomiting and volume depletion. Imaging studies revealed a soft tissue abscess in the left psoas major muscle.


METHODS
Physical examination, complete urine analysis, blood and urine cultures, measurement of peripheral eosinophil and plasma creatinine levels, and renal ultrasound.


METHODS
Nafcillin-associated acute interstitial nephritis.


RESULTS
Discontinuation of nafcillin and provision of supportive care.
Hoppes
Tobin
T
University of Vermont/FAHC, Department of Medicine, Division of Nephrology, Colchester, VT 05446, USA.
Prikis
Marios
M
Segal
Alan
A
D000208:Acute Disease; D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009254:Nafcillin / Q000009:adverse effects*; D009395:Nephritis, Interstitial / Q000139:chemically induced*
D000900:Anti-Bacterial Agents; D009254:Nafcillin