Implementation validation performed in Rwanda to determine whether the INNO-LiPA Rif.TB line probe assay can be used for detection of multidrug-resistant Mycobacterium tuberculosis in low-resource countries.
We validated the implementation of the INNO-LiPA Rif.TB line probe assay, a diagnostic test for rapid detection of multidrug-resistant tuberculosis (MDR-TB), in Rwanda. No substantial difference was found between results obtained in Rwanda and results obtained in Belgium with the same samples. This rapid diagnostic test for MDR-TB can therefore be reliably implemented in a resource-poor setting.
Quezada
Cindy Maria
CM
Laboratory of Structural Microbiology, Rockefeller University, New York, NY, USA.
Kamanzi
Eliane
E
Mukamutara
Julienne
J
De Rijk
Pim
P
Rigouts
Leen
L
Portaels
Françoise
F
Ben Amor
Yanis
Y
D001431:Bacteriological Techniques / Q000379:methods*; D001530:Belgium; D006801:Humans; D025202:Molecular Diagnostic Techniques / Q000379:methods*; D009169:Mycobacterium tuberculosis / Q000235:genetics / Q000302:isolation & purification*; D012432:Rwanda; D018088:Tuberculosis, Multidrug-Resistant / Q000175:diagnosis* / Q000382:microbiology*