Dietary counseling and probiotic supplementation during pregnancy modify placental phospholipid fatty acids.
It has previously been shown that maternal nutrition affects the fetal environment, with consequences for the infant's health. From early pregnancy onwards participants here received a combination of dietary counseling and probiotics (Lactobacillus GG and Bifidobacterium lactis Bb12; n = 10), dietary counseling with placebo (n = 12), or placebo alone (n = 8). The major differences in placental fatty acids were attributable to a higher concentration of n-3 polyunsaturated fatty acids in both intervention arms than in controls. Further, dietary counseling with probiotics resulted in higher concentrations of linoleic (18:2n-6) and dihomo-gamma-linolenic acids (20:3n-6) compared with dietary counseling with placebo or controls.
Kaplas
Niina
N
Functional Foods Forum, University of Turku, 20014, Turku, Finland.
Isolauri
Erika
E
Lampi
Anna-Maija
AM
Ojala
Tiina
T
Laitinen
Kirsi
K
D003376:Counseling; D004041:Dietary Fats / Q000008:administration & dosage; D005231:Fatty Acids, Unsaturated / Q000032:analysis*; D005260:Female; D006801:Humans; D039382:Maternal Nutritional Physiological Phenomena; D008431:Maternal-Fetal Exchange; D010743:Phospholipids / Q000737:chemistry*; D010920:Placenta / Q000737:chemistry*; D011247:Pregnancy; D019936:Probiotics / Q000008:administration & dosage*
D004041:Dietary Fats; D005231:Fatty Acids, Unsaturated; D010743:Phospholipids