title: Bio-oxidation of tripropylene glycol under aerobic conditions.
abstract: Aerobic biodegradation of tripropylene glycol (PG3) was investigated under the conditions of the OECD screening test 301E and the Continuous Flow Activated Sludge Simulation test (CFAS). A modified two-chamber facility with a denitrification stage was used for the CFAS test. Primary PG3 biodegradation was measured by the HPLC with fluorimetric detection and analyte derivatisation. Metabolites were identified by LC-MS with electrospray ionisation and GC-MS with electron impact ionisation, as well as semiquantitatively determined by the LC-MS technique. PG3 was found to be inherently biodegradable and it exhibits a strong poisonous effect on activated sludge after exceeding the threshold concentration (10 mg l(-1)). Metabolite accumulation onto the activated sludge is probably responsible for this poisonous effect. Probable biotransformation products of tripropylene glycol under the aerobic conditions include metabolites with a single terminal aldehyde or a ketone group and metabolites with two terminal aldehyde or ketone groups. Their concentration rises at the end of the OECD screening test.
authors.affiliation: Institute of Chemistry, Poznan University of Technology, Piotrowo 3, Poznan 60-965, Poland.
authors.forename: Agnieszka
authors.initials: A
authors.lastname: Zgoła-Grześkowiak
authors.forename: Tomasz
authors.initials: T
authors.lastname: Grześkowiak
authors.forename: Joanna
authors.initials: J
authors.lastname: Zembrzuska
authors.forename: Magdalena
authors.initials: M
authors.lastname: Frańska
authors.forename: Rafał
authors.initials: R
authors.lastname: Frański
authors.forename: Zenon
authors.initials: Z
authors.lastname: Lukaszewski
mesh_terms: D000332:Aerobiosis; D008401:Gas Chromatography-Mass Spectrometry; D015394:Molecular Structure; D010084:Oxidation-Reduction; D011409:Propylene Glycols / Q000378:metabolism*; D012722:Sewage
chemical_list: D011409:Propylene Glycols; D012722:Sewage; C578961:tripropylene glycol