title: Prostate cancer with supraclavicular lymphadenopathy and bulky abdominal tumor.
abstract: A 73-year-old man with suspected lymphoproliferative disorder was introduced to our hospital. The patient demonstrated palpable hard masses in the abdomen. Enhanced computed tomography of the abdomen and pelvis revealed a bulky mass of para-aortic lymph nodes. Biopsy of left-sided supraclavicular lymph nodes revealed metastatic adenocarcinoma. Serum tumor markers were examined, revealing prostate-specific antigen (PSA) levels of 3,354.0 ng/ml. Rectal examinations revealed a stony-hard prostatic mass. Biopsy of the prostate disclosed poorly to moderately differentiated adenocarcinoma. Although metastases to the supraclavicular lymph nodes are rare in prostate cancer, it should be distinguished from malignant lymphoma and other malignancies.
authors.affiliation: Division of Hematology, Kawaguchi Municipal Medical Center. s.kosugi@city.kawaguchi.saitama.jp
authors.forename: Shigeki
authors.initials: S
authors.lastname: Kosugi
authors.forename: Syoko
authors.initials: S
authors.lastname: Mizumachi
authors.forename: Akiko
authors.initials: A
authors.lastname: Kitajima
authors.forename: Takumi
authors.initials: T
authors.lastname: Igarashi
authors.forename: Takamasa
authors.initials: T
authors.lastname: Hamada
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Kaya
authors.forename: Kazunao
authors.initials: K
authors.lastname: Kurihara
authors.forename: Koji
authors.initials: K
authors.lastname: Ogasawara
authors.forename: Hitomi
authors.initials: H
authors.lastname: Sakata
authors.forename: Masahiro
authors.initials: M
authors.lastname: Yamamoto
authors.forename: Mamoru
authors.initials: M
authors.lastname: Nagamine
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Yamazaki
mesh_terms: D000008:Abdominal Neoplasms / Q000175:diagnosis / Q000556:secondary* / Q000628:therapy; D000230:Adenocarcinoma / Q000175:diagnosis / Q000556:secondary* / Q000628:therapy; D000368:Aged; D003937:Diagnosis, Differential; D006801:Humans; D008207:Lymphatic Metastasis; D008223:Lymphoma / Q000175:diagnosis; D008297:Male; D017430:Prostate-Specific Antigen / Q000097:blood; D011471:Prostatic Neoplasms / Q000097:blood / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy; D016896:Treatment Outcome
chemical_list: D017430:Prostate-Specific Antigen