title: Aminoglycoside resistance in members of the Staphylococcus sciuri group.
abstract: This study investigated the prevalence of aminoglycoside resistance and genes encoding aminoglycoside-modifying enzymes in members of the Staphylococcus sciuri group. A total of 304 S. sciuri group member isolates (284 S. sciuri, 12 S. lentus, and 8 S. vitulinus) from humans (n = 34), animals (n = 133), and environmental sources (n = 137; out-hospital and hospital environment, food) were examined for their susceptibility to amikacin, gentamicin, isepamicin, kanamycin, neomycin, netilmicin, sisomicin, streptomycin, and tobramycin. The overall prevalence of resistance to aminoglycosides was low at 12.1%. Resistance to single aminoglycosides ranged from 0% to 7.2%. The aac(6')-Ie/aph(2"), ant(4')-Ia, and aph(3')-IIIa genes, either alone or in combination, were found in 16 out of 19 isolates showing resistance to nonstreptomycin aminoglycosides. Among the 22 isolates that showed resistance to streptomycin, the genes str and ant(6)-Ia were identified in 18 and 4 isolates, respectively.
authors.affiliation: Department of Microbiology, Institute of Biology, University of Bialystok, 15-950 Bialystok, Poland.
authors.forename: Tomasz
authors.initials: T
authors.lastname: Hauschild
authors.forename: Dragana
authors.initials: D
authors.lastname: Vuković
authors.forename: Ivana
authors.initials: I
authors.lastname: Dakić
authors.forename: Petr
authors.initials: P
authors.lastname: Jezek
authors.forename: Slobodanka
authors.initials: S
authors.lastname: Djukić
authors.forename: Vladimir
authors.initials: V
authors.lastname: Dimitrijević
authors.forename: Srdjan
authors.initials: S
authors.lastname: Stepanović
authors.forename: Stefan
authors.initials: S
authors.lastname: Schwarz
mesh_terms: D000617:Aminoglycosides / Q000494:pharmacology*; D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001431:Bacteriological Techniques; D024901:Drug Resistance, Multiple, Bacterial; D016521:Electrophoresis, Gel, Pulsed-Field; D005516:Food Microbiology; D006761:Hospitals; D006801:Humans; D016133:Polymerase Chain Reaction; D013210:Staphylococcus / Q000187:drug effects* / Q000201:enzymology / Q000235:genetics
chemical_list: D000617:Aminoglycosides; D000900:Anti-Bacterial Agents