title: Management of non-ST-Segment Elevation Myocardial Infarction.
abstract: Non-ST-segment elevation myocardial infarction (NSTEMI) is a major cause of cardiovascular morbidity and mortality in the United States. It represents the highest risk category of non-ST-segment elevation acute coronary syndromes (NSTEACS), for which timely diagnosis and appropriate therapy are paramount to improve outcomes. Evidence-based treatment, with combination of antiplatelet and anticoagulant therapy, and with serious consideration of early coronary angiography and revascularization along with anti-ischemic medical therapy, is the mainstay of management for NSTEMI. Aggressive risk-factor control after the acute event is imperative for secondary prevention of cardiovascular events. Applying in practice the American College of Cardiology/American Heart Association (ACC/AHA) guideline recommendations results in improved outcomes.
authors.affiliation: Division of Cardiology, Medical University of South Carolina, 135 Rutledge Avenue, Suite 1201, P.O. Box 250592, Charleston, SC 29425, USA.
authors.forename: Stephen E
authors.initials: SE
authors.lastname: Van Horn
authors.forename: Calin V
authors.initials: CV
authors.lastname: Maniu
mesh_terms: D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use; D000701:Analgesics, Opioid / Q000627:therapeutic use; D000789:Angina, Unstable / Q000628:therapy*; D002121:Calcium Channel Blockers / Q000627:therapeutic use; D017023:Coronary Angiography; D006401:Hematologic Agents / Q000627:therapeutic use; D006801:Humans; D000960:Hypolipidemic Agents / Q000627:therapeutic use; D008019:Life Style; D009020:Morphine / Q000627:therapeutic use; D009203:Myocardial Infarction / Q000628:therapy*; D009204:Myocardial Revascularization; D005996:Nitroglycerin / Q000627:therapeutic use; D019039:Platelet Glycoprotein GPIIb-IIIa Complex / Q000037:antagonists & inhibitors; D018570:Risk Assessment; D014665:Vasodilator Agents / Q000627:therapeutic use
chemical_list: D000319:Adrenergic beta-Antagonists; D000701:Analgesics, Opioid; D002121:Calcium Channel Blockers; D006401:Hematologic Agents; D000960:Hypolipidemic Agents; D019039:Platelet Glycoprotein GPIIb-IIIa Complex; D014665:Vasodilator Agents; D009020:Morphine; D005996:Nitroglycerin