Stereoselective synthesis of 1,2-aminoalcohols by [2,3]-wittig rearrangements.
[2,3]-Wittig rearrangements of (E)-3-aza-allylic alcohol derivatives can provide access to functionalized 1,2-aminoalcohols with high syn or anti diastereoselectivity depending on the anionic stabilizing group (amide or alkyne).
Barbazanges
Marion
M
Laboratoire de Chimie Organique, ESPCI, CNRS, 10 rue Vauquelin 75231 Paris Cedex 05, France.
Meyer
Christophe
C
Cossy
Janine
J
D000438:Alcohols; D000480:Alkynes; D000577:Amides; D000605:Amino Alcohols / Q000138:chemical synthesis*; D013237:Stereoisomerism
D000438:Alcohols; D000480:Alkynes; D000577:Amides; D000605:Amino Alcohols