title: Remitting seronegative symmetrical synovitis with pitting edema (RS3PE) syndrome accompanied by Parkinson's disease.
abstract: We encountered two cases of RS3PE (remitting seronegative symmetrical synovitis with pitting edema) syndrome accompanied by Parkinson's disease (PD). Although the etiology of RS3PE syndrome is still unknown, several possible associations, such as malignancies and viral infections, have been reported; RS3PE syndrome is thought to be an autoimmune-mediated disorder. The present patients did not have any factors which are reported to be associated with RS3PE. Whether or not the complication of PD and RS3PE syndrome is incidental needs to be further examined, and we discuss here the possible cause of association between PD and RS3PE syndrome, including dopamine agonists one of the anti-PD medications.
authors.affiliation: Department of Neurology, Neurological Institute, Tokyo Women's Medical University.
authors.forename: Eiichi
authors.initials: E
authors.lastname: Ito
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Okamoto
authors.forename: Atsuko
authors.initials: A
authors.lastname: Mochizuki
authors.forename: Kuniko
authors.initials: K
authors.lastname: Ohara
authors.forename: Maiko
authors.initials: M
authors.lastname: Kato
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Terashima
authors.forename: Eiichi
authors.initials: E
authors.lastname: Tanaka
authors.forename: Kae
authors.initials: K
authors.lastname: Takagi
authors.forename: Shinichiro
authors.initials: S
authors.lastname: Uchiyama
authors.forename: Makoto
authors.initials: M
authors.lastname: Iwata
mesh_terms: D000368:Aged; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D001172:Arthritis, Rheumatoid / Q000175:diagnosis; D003937:Diagnosis, Differential; D004487:Edema / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D005260:Female; D005528:Foot; D006225:Hand; D006801:Humans; D008297:Male; D008875:Middle Aged; D010300:Parkinson Disease / Q000150:complications* / Q000628:therapy; D011239:Prednisolone / Q000627:therapeutic use; D013577:Syndrome; D013585:Synovitis / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D016896:Treatment Outcome
chemical_list: D000893:Anti-Inflammatory Agents; D011239:Prednisolone