title: [Case of advanced gastric cancer successfully treated with chemotherapy of weekly paclitaxel].
abstract: We report a case of gastric cancer with ascites treated with chemotherapy. The patient is a 67-year-old male. Combination chemotherapy of S-1 and CDDP was given as the first-line treatment. However, the symptoms did not improve with that regimen, so we decided to change the chemotherapy to paclitaxel as second-line treatment. After 4 cycles, CT scan revealed decreasing ascites and endoscopy a reduction of the primary tumor. The patient has maintained a condition of decreasing ascites with improvement of QOL for 8 months. This regimen is considered effective treatment for unresectable gastric cancer.
authors.affiliation: Dept. of Gastroenterology, Ohno-Kinen Hospital.
authors.forename: Kyoko
authors.initials: K
authors.lastname: Fujii
authors.forename: Hironori
authors.initials: H
authors.lastname: Uno
authors.forename: Soichiro
authors.initials: S
authors.lastname: Kayo
authors.forename: Yoshio
authors.initials: Y
authors.lastname: Ueda
authors.forename: Chika
authors.initials: C
authors.lastname: Kawamura
authors.forename: Yoko
authors.initials: Y
authors.lastname: Mizuyama
authors.forename: Koji
authors.initials: K
authors.lastname: Kaneda
authors.forename: Hiroji
authors.initials: H
authors.lastname: Nakagawa
authors.forename: Tetsuo
authors.initials: T
authors.lastname: Arakawa
mesh_terms: D000230:Adenocarcinoma / Q000188:drug therapy* / Q000556:secondary; D000368:Aged; D000972:Antineoplastic Agents, Phytogenic / Q000008:administration & dosage*; D002945:Cisplatin; D004334:Drug Administration Schedule; D004338:Drug Combinations; D019008:Drug Resistance, Neoplasm; D006801:Humans; D007262:Infusions, Intravenous; D008297:Male; D010094:Oxonic Acid; D017239:Paclitaxel / Q000008:administration & dosage*; D010534:Peritoneal Neoplasms / Q000188:drug therapy / Q000556:secondary; D013274:Stomach Neoplasms / Q000188:drug therapy* / Q000473:pathology; D005641:Tegafur
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D004338:Drug Combinations; C079198:S 1 (combination); D005641:Tegafur; D010094:Oxonic Acid; D017239:Paclitaxel; D002945:Cisplatin