Intracerebral Hodgkin's lymphoma in a patient with human immunodeficiency virus.
Central nervous system (CNS) involvement by Hodgkin Lymphoma (HL) is rarely reported. Retrospective and prospective cohort studies suggest an incidence of 0.2-0.5%, mostly in relapsed disease. In spite of a 3 to 18-fold increased risk of HL in patients with human immunodeficiency virus (HIV), only two cases have been reported so far. In this paper, we now report a third case of HIV patient with HL who progressed with isolated CNS infiltration after a standard chemotherapy induced clinical remission. In 1991, when the first case of intracerebral involvement in HIV+ HL was reported an increase of this type of cases would have been expected, but only one more case has been reported since then.
García-Noblejas
A
A
Department of Hematology, La Princesa Hospital, Spain.
Nieto
S
S
Liberal
R
R
Cannata
J
J
Steegmann
J L
JL
Fernàndez-Rañada
J M
JM
Arranz
R
R
D000328:Adult; D001932:Brain Neoplasms / Q000150:complications / Q000473:pathology*; D006678:HIV; D015658:HIV Infections / Q000150:complications / Q000473:pathology*; D006689:Hodgkin Disease / Q000150:complications / Q000473:pathology*; D006801:Humans; D008297:Male