Use of octreotide acetate to prevent rebound hypoglycaemia in sulfonylurea overdose.
A short cut review was carried out to establish whether octreotide can prevent rebound hypoglycaemia after sulfonylurea overdose. Fourteen papers were found using the reported searches, of which two presented the best evidence to answer the clinical question. The author, date and country of publication, patient group studied, study type, relevant outcomes, results and study weaknesses of these best papers are summarised in table 2. It is concluded that octreotide may be safe and effective in this situation.
Hassan
Ziauddin
Z
Registrar in Emergency Medicine, Newcastle General Hospital, Newcastle, UK.
Wright
John
J
D000293:Adolescent; D000328:Adult; D000368:Aged; D062787:Drug Overdose / Q000150:complications; D004359:Drug Therapy, Combination; D005765:Gastrointestinal Agents / Q000627:therapeutic use*; D005947:Glucose / Q000627:therapeutic use; D006801:Humans; D007003:Hypoglycemia / Q000188:drug therapy* / Q000209:etiology; D008875:Middle Aged; D015282:Octreotide / Q000627:therapeutic use*; D013453:Sulfonylurea Compounds / Q000506:poisoning*; D016896:Treatment Outcome
D005765:Gastrointestinal Agents; D013453:Sulfonylurea Compounds; D005947:Glucose; D015282:Octreotide