Effects of Ballota nigra on glucose and insulin in alloxan-diabetic albino rats.
The hypoglycemic effect of Ballota nigra extract on albino rats was investigated. Alloxan-induced diabetes mellitus was accompanied by several fold increases in plasma glucose. Administration of aqueous extract of B. nigra extract significantly reduced glucose in both healthy and diabetic rats. These results suggest that B. nigra possess hypoglycemic effects in rats and therefore, can be useful for the treatment of diabetes mellitus.
Nusier
Mohamad K
MK
Department of Biochemistry and Molecular Biology, School of Medicine, Jordan University of Science and Technology, Irbid 22110, Jordan. mick@just.edu.jo
Bataineh
Hameed N
HN
Bataineh
Ziad M
ZM
Daradka
Haytham M
HM
D000284:Administration, Oral; D000417:Albinism / Q000235:genetics; D000496:Alloxan; D000818:Animals; D031329:Ballota; D001786:Blood Glucose / Q000378:metabolism*; D003921:Diabetes Mellitus, Experimental / Q000097:blood*; D005260:Female; D007004:Hypoglycemic Agents / Q000008:administration & dosage / Q000494:pharmacology; D007328:Insulin / Q000097:blood*; D008297:Male; D010936:Plant Extracts / Q000008:administration & dosage / Q000494:pharmacology*; D051381:Rats; D011922:Rats, Mutant Strains
D001786:Blood Glucose; D007004:Hypoglycemic Agents; D007328:Insulin; D010936:Plant Extracts; D000496:Alloxan