Aptamer-based strategies for stem cell research.
Aptamers have been introduced to analytical applications, target validation, and drug discovery processes and, recently, applied directly as therapeutic agents. Aptamers can be generated by a method called SELEX (Systematic Evolution of Ligands by Exponential Enrichment). This is quite remarkable for such a young technology, which is only created in the early 1990s. This paper reviews recent new applications of aptamers in stem cell research and tissue engineering.
Guo
Ke-Tai
KT
Department of Thoracic, University Hospital of Tuebingen, Tuebingen, Germany.
Schäfer
Richard
R
Paul
Angela
A
Ziemer
Gerhard
G
Wendel
Hans P
HP
D000818:Animals; D052157:Aptamers, Nucleotide / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D018929:Cell Culture Techniques; D006801:Humans; D059630:Mesenchymal Stem Cells; D012106:Research; D052156:SELEX Aptamer Technique; D023822:Tissue Engineering / Q000379:methods*
D052157:Aptamers, Nucleotide