title: Auditory brainstem response in premature and full-term children.
abstract: OBJECTIVE
  To compare the absolute latencies of peaks I, III and V and interpeak intervals of premature and full-term children.
  
  
  METHODS
  Prospective, comparative cohort study. Study subjects were premature and full-term children with auditory brainstem response (ABR) measured at ages 4, 12 and 20 months. The children had previously undergone otorhinolaryngolic and audiologic evaluations to exclude those with altered hearing.
  
  
  RESULTS
  One hundred and twenty-four children were included in the study (73 premature). No differences were found between children of different sexes nor between the right and left ears of the individual children, so the statistical unit sed for the study was the ear. Using the t-test for independent samples, the absolute latencies of peaks I, III and IV and the interpeak intervals I-III, I-IV and III-V presented statistically significant differences between the groups at ages 4 and 12 months. At 20 months, only peak I failed to show a difference in absolute latency. Strong inverse correlation was found (Pearson's coefficient) between gestational age and absolute peak latency, as well as for interpeak intervals.
  
  
  CONCLUSIONS
  Maturation of the auditory system, as measured by ABR, occurs differently between premature and full-term children, suggesting that gestational age be taken into consideration when using ABR in premature children younger than 20 months old.
authors.affiliation: Hospital de Clinicas de Porto Alegre, Department of Othorhinolaringology, Av. Lavras 584 apto 302, 90000000 Porto Alegre, Rio Grande do Sul, Brazil. pricilasleifer@uol.com.br
authors.forename: Pricila
authors.initials: P
authors.lastname: Sleifer
authors.forename: Sady Selaimen
authors.initials: SS
authors.lastname: da Costa
authors.forename: Pedro Luiz
authors.initials: PL
authors.lastname: Cóser
authors.forename: Marcelo Zubaran
authors.initials: MZ
authors.lastname: Goldani
authors.forename: Cristina
authors.initials: C
authors.lastname: Dornelles
authors.forename: Kátia
authors.initials: K
authors.lastname: Weiss
mesh_terms: D002648:Child; D002675:Child, Preschool; D015331:Cohort Studies; D016057:Evoked Potentials, Auditory, Brain Stem / Q000502:physiology*; D005260:Female; D005865:Gestational Age; D006311:Hearing Disorders / Q000175:diagnosis / Q000453:epidemiology* / Q000503:physiopathology*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007234:Infant, Premature; D008297:Male; D008403:Mass Screening / Q000295:instrumentation; D011446:Prospective Studies