title: Prostate-sparing cystectomy: has Pandora's box been opened?
abstract: En bloc removal of the prostate has traditionally been an integral component of radical cystectomy for men with bladder cancer owing to a high incidence of occult prostatic malignancy. However, the risk of functional morbidity following this procedure is considerable and can delay patient acceptance of cystectomy, which can adversely affect the long-term prognosis. Recently, some investigators have advocated prostate-sparing cystectomy (PSCx) to improve postoperative continence and potency rates, and this may also improve timely patient acceptance of cystectomy. Several of these PSCx series describe excellent functional results postoperatively and PSCx may also facilitate a laparoscopic approach, offering further dividends. However, valid concerns regarding the oncologic efficacy of this procedure still predominate and protocols for patient selection, technique and postoperative surveillance are not well defined. The concept of PSCx is arguably one of the most controversial topics in the field of bladder cancer today.
authors.affiliation: Glickman Urological Institute, Cleveland Clinic Foundation, Cleveland, OH 44195, USA. keferj@ccf.org
authors.forename: John C
authors.initials: JC
authors.lastname: Kefer
authors.forename: Edward E
authors.initials: EE
authors.lastname: Cherullo
authors.forename: J Stephen
authors.initials: JS
authors.lastname: Jones
authors.forename: Michael C
authors.initials: MC
authors.lastname: Gong
authors.forename: Steven C
authors.initials: SC
authors.lastname: Campbell
mesh_terms: D015653:Cystectomy / Q000009:adverse effects / Q000379:methods*; D007172:Erectile Dysfunction / Q000209:etiology / Q000517:prevention & control; D006801:Humans; D008297:Male; D011467:Prostate; D013997:Time Factors; D001749:Urinary Bladder Neoplasms / Q000601:surgery*; D014549:Urinary Incontinence / Q000209:etiology / Q000517:prevention & control