Neural decision boundaries for maximal information transmission.
We consider here how to separate multidimensional signals into two categories, such that the binary decision transmits the maximum possible information about those signals. Our motivation comes from the nervous system, where neurons process multidimensional signals into a binary sequence of responses (spikes). In a small noise limit, we derive a general equation for the decision boundary that locally relates its curvature to the probability distribution of inputs. We show that for Gaussian inputs the optimal boundaries are planar, but for non-Gaussian inputs the curvature is nonzero. As an example, we consider exponentially distributed inputs, which are known to approximate a variety of signals from natural environment.
Sharpee
Tatyana
T
Crick-Jacobs Center for Theoretical Biology and Laboratory of Computational Neurobiology, Salk Institute for Biological Studies, La Jolla, California, United States of America. sharpee@salk.edu
Bialek
William
W
D000818:Animals; D003657:Decision Making; D001330:Electronic Data Processing / Q000379:methods*; D019277:Entropy; D006801:Humans; D007858:Learning; D008959:Models, Neurological; D009415:Nerve Net; D009424:Nervous System Physiological Phenomena; D009474:Neurons / Q000502:physiology; D016011:Normal Distribution; D011336:Probability; D015398:Signal Transduction / Q000502:physiology*; D013028:Space Perception; D009435:Synaptic Transmission / Q000502:physiology*; D014796:Visual Perception / Q000502:physiology