title: [Study on effect of different extracts in curcuma long on stability of curcumin].
abstract: OBJECTIVE
  To investigate effects of different extracted fractions from Curcumia long on the stability of curcumin. There are some constituents that can stabilize curcumin.
  
  
  METHODS
  To add the extracts obtained from C. long were water, alcohol, acetone, ether, ethyl acetate, petroleum ether to pure solution of curcumin. To determine the change of curcumin by high performance liquid chromatography (HPLC). To investigate the dynamics of curcumin degradation.
  
  
  RESULTS
  The stability obtained from alcohol, acetone, ether, ethyl ether all improved the stabilization of curcumin. 80% Alcohol extract had the optimal stabilizineg ability for curcumin.
  
  
  CONCLUSIONS
  The extracts from alcohol are more stable than pure curcumin at same conditions. The stability of curcumin is improved by alcohol extracts.
authors.affiliation: Pharmaceutical Department, North China Coal Medical College, Tangshan Key Laboratory of New Drug Research, Tangshan 063000, China. tsyxhg@163.com
authors.forename: Gang
authors.initials: G
authors.lastname: Han
authors.forename: Zheng-Meng
authors.initials: ZM
authors.lastname: Liu
authors.forename: Xiao-Yan
authors.initials: XY
authors.lastname: Wang
authors.forename: Yan-Nan
authors.initials: YN
authors.lastname: Wang
mesh_terms: D002851:Chromatography, High Pressure Liquid; D030024:Curcuma / Q000737:chemistry*; D003474:Curcumin / Q000737:chemistry / Q000302:isolation & purification*; D004355:Drug Stability; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification; D000431:Ethanol / Q000737:chemistry; D006863:Hydrogen-Ion Concentration; D010946:Plants, Medicinal / Q000737:chemistry*; D027343:Rhizome / Q000737:chemistry; D013678:Technology, Pharmaceutical / Q000379:methods
chemical_list: D004365:Drugs, Chinese Herbal; D000431:Ethanol; D003474:Curcumin