Burkitt's lymphoma of the duodenum in a patient with AIDS.
Non-Hodgkin's lymphoma of B-cell type is the second most common neoplasm after Kaposi's sarcoma, among patients with human immunodeficiency virus infection. Most non-Hodgkin's lymphoma cases that are associated with acquired immunodeficiency syndrome involve extranodal sites, especially the digestive tract and the central nervous system. We report a case of primary lymphoma of the duodenum in a patient with AIDS. Upper gastrointestinal endoscopy revealed pseudopolypoid masses found in the second portion of the duodenum. A complete diagnostic study including histological, immunohistochemical and virological analyses showed high-grade B-cell Burkitt's lymphoma. The Epstein-Barr virus genome was detected in biopsies by immunohistochemical and in situ hybridization.
Corti
Marcelo
M
Division of HIV/AIDS disease, F. J. Muñiz Infectious Diseases Hospital, Buenos Aires, Argentina. marcelocorti@fibertel.com.ar
Villafañe
María Florencia
MF
Souto
Liliana
L
Schtirbu
Ricardo
R
Narbaitz
Marina
M
Soler
Marcela de Dios
Mde D
D002051:Burkitt Lymphoma / Q000175:diagnosis*; D004379:Duodenal Neoplasms / Q000175:diagnosis* / Q000821:virology; D017809:Fatal Outcome; D016679:Genome, Viral; D004854:Herpesvirus 4, Human / Q000235:genetics; D006801:Humans; D017403:In Situ Hybridization; D016483:Lymphoma, AIDS-Related / Q000175:diagnosis* / Q000821:virology; D008297:Male; D008875:Middle Aged