Monozygotic triplet pregnancy following egg donation and transfer of single frozen-thawed embryo.
OBJECTIVE
To describe a case of monozygotic triplet pregnancy following egg donation and the transfer of a single frozen-thawed embryo.


METHODS
Case report.


METHODS
District general hospital and regional department of fetal medicine in northeast England.


METHODS
A 38-year-old woman with a 2-year history of primary infertility due to severe endometriosis and poor ovarian reserve who conceived after egg donation and transfer of a single frozen-thawed embryo.


METHODS
Transfer of a single frozen-thawed embryo and delivery of three identical female infants by emergency caesarean section because of preterm labor at 32 weeks' gestation.


METHODS
Review of effect of assisted conception on monozygotic twinning rates.


RESULTS
Healthy outcome for all three infants.


CONCLUSIONS
Assisted reproductive treatments may lead to disturbances in zona pellucida architecture and an increase in monozygotic twinning rates. Couples need to be informed of this and the increased risks associated with these pregnancies before they begin with treatment.
Faraj
Radwan
R
Centre for Assisted Reproduction, Queen Elizabeth Hospital, Gateshead, Washington. Electronic address: faraj68@hotmail.com.
Evbuomwan
Isaac
I
Cromwell IVF and Fertility Centre, BUPA Hospital, Washington.
Sturgiss
Stephen
S
Department of Fetal Medicine, Royal Victoria Infirmary, Newcastle-upon-Tyne, United Kingdom.
Aird
Ian
I
Centre for Assisted Reproduction, Queen Elizabeth Hospital, Gateshead, Washington.
D000328:Adult; D004624:Embryo Transfer / Q000379:methods*; D004715:Endometriosis / Q000150:complications; D005260:Female; D006801:Humans; D007247:Infertility, Female / Q000209:etiology / Q000628:therapy*; D018587:Oocyte Donation / Q000379:methods*; D011247:Pregnancy; D011256:Pregnancy Outcome; D016896:Treatment Outcome; D014310:Triplets