[The optimum condition on baicalin extraction from Scutellaria baicalensis].
OBJECTIVE
To optimize the extraction process of baicalin from Scutellaria Baicalensis Georgi with ethanol.


METHODS
The extraction process of baicalin from Scutellaria Baicalensis Georgi was optimized with the aid of orthogonal experiments.


RESULTS
The optimal parameters were obtained as follows: extracting temperature, extracting time, ethanol concentration and mechanical stirring speed were 80 degrees C, 1 h, 60% and 400 r/min, respectively. The extracting rate of baicalin was 83.90%.


CONCLUSIONS
Comparing ethanol circumfluence, boiling water, ultrasonic wave and semi-bionic on extracting baicalin from Scutellaria baicalensis Georgi, the ethanol circumfluence extraction is better than other technological conditions on extracting baicalin.
Zhou
Fang
F
Hubei Key Lab of Novel Reactor & Green Chemical Technology, Wuhan Institute of Technology, Wuhan 430073, China.
Chi
Ru-an
RA
Wu
Yuan-xin
YX
Ju
Xiu-lian
XL
Guo
Jia
J
Huang
Qi-mao
QM
D004365:Drugs, Chinese Herbal; D000431:Ethanol; D005419:Flavonoids / Q000302:isolation & purification*; D010936:Plant Extracts / Q000737:chemistry*; D031364:Scutellaria baicalensis / Q000737:chemistry*
D004365:Drugs, Chinese Herbal; D005419:Flavonoids; D010936:Plant Extracts; C499814:Scutellaria baicalensis extract; C038044:baicalin; D000431:Ethanol