title: Influence of a performance-improvement initiative on quality of care for patients hospitalized with heart failure: results of the Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients With Heart Failure (OPTIMIZE-HF).
abstract: BACKGROUND
  Despite evidence-based national guidelines for optimal treatment of heart failure (HF), the quality of care remains inadequate. We sought to evaluate the effect of a national hospital-based initiative on quality of care in patients hospitalized with HF.
  
  
  METHODS
  Two hundred fifty-nine US hospitals participating in the Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients With Heart Failure (OPTIMIZE-HF) submitted data on 48 612 patients with HF from March 1, 2003, through December 31, 2004. Admission, hospital, discharge care, and outcomes data were collected using a Web-based registry that provided real-time feedback on performance measures benchmarked to other hospitals. Process-of-care improvement tools, including evidence-based best-practice algorithms and customizable admission and discharge sets, were provided.
  
  
  RESULTS
  Provision of complete discharge instructions and smoking-cessation counseling increased significantly (from 46.8%-66.5% and 48.2%-75.6%, respectively; P < .001 for both). Left ventricular function assessment started at a high rate (89.3%) and improved to 92.1% (P < .001). Angiotensin-converting enzyme inhibitors were prescribed at discharge to 75.8% of eligible patients, which did not improve during the 2-year study. There were trends for reduction of in-hospital mortality, postdischarge death, and combined postdischarge death and rehospitalization and a significant reduction in mean length of stay. Use of preprinted admission order sets and/or discharge checklists increased from 35.6% to 54.1% and was associated with an increase in the use of evidence-based therapies and lower risk-adjusted in-hospital mortality.
  
  
  CONCLUSIONS
  Participation in OPTIMIZE-HF was associated with an increase in use of evidence-based therapy, adherence to performance measures, and shorter lengths of stay in patients hospitalized with HF. Increased use of process-of-care improvement tools was associated with further improvements in quality of care.
  
  
  BACKGROUND
  clinicaltrials.gov Identifier NCT00344513.
authors.affiliation: Department of Medicine, University of California-Los Angeles Medical Center, 10833 LeConte Ave, Room 47-123 CHS, Los Angeles, CA 90095-1679, USA. gfonarow@mednet.ucla.edu
authors.forename: Gregg C
authors.initials: GC
authors.lastname: Fonarow
authors.forename: William T
authors.initials: WT
authors.lastname: Abraham
authors.forename: Nancy M
authors.initials: NM
authors.lastname: Albert
authors.forename: Wendy
authors.initials: W
authors.lastname: Gattis Stough
authors.forename: Mihai
authors.initials: M
authors.lastname: Gheorghiade
authors.forename: Barry H
authors.initials: BH
authors.lastname: Greenberg
authors.forename: Christopher M
authors.initials: CM
authors.lastname: O'Connor
authors.forename: Karen
authors.initials: K
authors.lastname: Pieper
authors.forename: Jie Lena
authors.initials: JL
authors.lastname: Sun
authors.forename: Clyde W
authors.initials: CW
authors.lastname: Yancy
authors.forename: James B
authors.initials: JB
authors.lastname: Young
mesh_terms: D000368:Aged; D000465:Algorithms; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000627:therapeutic use; D019317:Evidence-Based Medicine; D005260:Female; D006333:Heart Failure / Q000628:therapy*; D006760:Hospitalization; D006801:Humans; D007902:Length of Stay; D008297:Male; D009026:Mortality; D010359:Patient Readmission; D011787:Quality of Health Care; D016540:Smoking Cessation; D016277:Ventricular Function, Left
chemical_list: D000806:Angiotensin-Converting Enzyme Inhibitors