title: Flavan-3-ol-phenylpropanoid conjugates from Anemopaegma arvense and their antioxidant activities.
abstract: One of the species of commercially available catuaba was identified as Anemopaegma arvense by comparison of its micromorphological characteristics and TLC profile with six species of authenticated plants that are commonly referred to as catuaba. The bioactivity-guided fractionation of the ethyl acetate extract of the stem bark of this catuaba sample resulted in the isolation of one new (1, catuabin A) and three known flavan-3-ol type phenylpropanoids, cinchonain Ia (2), cinchonain IIa (3), and kandelin A1 (4) with antioxidant activities. The structures of these compounds were determined by a combination of spectroscopic techniques. Additionally, these compounds were tested for their anti-inflammatory, cytotoxicity, antimalarial, and antimicrobial activities, where no activity was observed.
authors.affiliation: USDA-ARS-NPURU, The University of Mississippi, USA.
authors.forename: Nurhayat
authors.initials: N
authors.lastname: Tabanca
authors.forename: Rahul S
authors.initials: RS
authors.lastname: Pawar
authors.forename: Daneel
authors.initials: D
authors.lastname: Ferreira
authors.forename: Jannie P
authors.initials: JP
authors.lastname: Marais
authors.forename: Shabana I
authors.initials: SI
authors.lastname: Khan
authors.forename: Vaishali
authors.initials: V
authors.lastname: Joshi
authors.forename: David E
authors.initials: DE
authors.lastname: Wedge
authors.forename: Ikhlas A
authors.initials: IA
authors.lastname: Khan
mesh_terms: D000975:Antioxidants / Q000008:administration & dosage / Q000737:chemistry / Q000494:pharmacology* / Q000627:therapeutic use; D029402:Bignoniaceae; D005419:Flavonoids / Q000008:administration & dosage / Q000737:chemistry / Q000494:pharmacology / Q000627:therapeutic use; D006801:Humans; D008517:Phytotherapy; D024301:Plant Bark; D010936:Plant Extracts / Q000008:administration & dosage / Q000737:chemistry / Q000494:pharmacology* / Q000627:therapeutic use
chemical_list: D000975:Antioxidants; D005419:Flavonoids; D010936:Plant Extracts; C404987:flavan-3-ol