[Usefulness of combined positron emission tomography and computed tomography imaging in Erdheim-Chester disease].
BACKGROUND
Erdheim-Chester disease is a rare non-Langerhans form of histiocytosis. We report the use of combined fluorodeoxyglucose positron emission tomography and computed tomography (18F-FDG PET-CT) in this disease.


METHODS
Three men, aged from 55 to 74 years with confirmed Erdheim-Chester disease were included. 18F-FDG PET-CT allowed to detect visceral and vascular involvement of the disease which were overlooked with CT-scan or magnetic resonance imaging: left common carotid and ilio-femoral artery in one patient, coronary, femoral and tibia in the second, aortic, common carotid, femoral and mandibula in the remaining patient. Also, sequential 18F-FDG PET-CT was useful to appreciate treatment efficiency (decrease hyperfixation) and decide treatment modification (interferon alpha).


CONCLUSIONS
18F-FDG PET-CT combined imaging allows to assess the extent of involvement in Erdheim-Chester disease. 18F-FDG PET-CT may be also a useful tool in the management of Erdheim-Chester disease.
Girszyn
N
N
Service de médecine interne, hôpital Foch, 40, rue Worth, 92151 Suresnes cedex, France. girszyn_nicolas@yahoo.fr
Arnaud
L
L
Villain
D
D
Kahn
J-E
JE
Piette
A-M
AM
Bletry
O
O
D000368:Aged; D001013:Aorta, Thoracic / Q000000981:diagnostic imaging; D031249:Erdheim-Chester Disease / Q000000981:diagnostic imaging*; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008297:Male; D049268:Positron-Emission Tomography; D019275:Radiopharmaceuticals; D014057:Tomography, X-Ray Computed
D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18