title: The spirastrellolides: construction of the southern C(1)-C(25) fragment exploiting anion relay chemistry.
abstract: Effective construction of the southern C(1)-C(25) fragment of spirastrellolide A has been achieved. Central to this venture was the use of four dithiane unions, including the highly effective deployment of the anion relay chemistry (ARC) tactic recently introduced by our laboratory.
authors.affiliation: Department of Chemistry, Monell Chemical Senses Center, and Laboratory for Research on Structure of Matter, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA. smithab@sas.upenn.edu
authors.forename: Amos B
authors.initials: AB
authors.lastname: Smith
authors.forename: Dae-Shik
authors.initials: DS
authors.lastname: Kim
mesh_terms: D000818:Animals; D000838:Anions; D018942:Macrolides / Q000138:chemical synthesis*; D011161:Porifera / Q000737:chemistry; D011807:Quinolizines / Q000737:chemistry; D013141:Spiro Compounds; D013457:Sulfur Compounds / Q000737:chemistry
chemical_list: D000838:Anions; D018942:Macrolides; D011807:Quinolizines; D013141:Spiro Compounds; D013457:Sulfur Compounds; C438055:dithiane; C475125:spirastrellolide A