Spatial neglect during electrocortical stimulation mapping in the right hemisphere.
Spatial processing was assessed following implantation of subdural electrodes in the nondominant hemisphere with electrocortical stimulation mapping (ESM) in two patients before epilepsy surgery. The first patient had mild hemispatial neglect/extinction during ESM of posterior temporal and inferior parietal areas. These areas were resected, and the patient had postoperative deficits that were similar to those occurring with ESM. The second patient was found to have marked hemispatial neglect during stimulation of parietal areas. These areas were not resected, and the patient had no neglect following surgery. These results suggest that ESM can help predict spatial processing deficits associated with cortical resection, and may help prevent postoperative impairments following resection in right parietal or temporal regions.
Kleinman
Jonathan T
JT
Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA.
Sepkuty
Jehuda P
JP
Hillis
Argye E
AE
Lenz
Frederick A
FA
Heidler-Gary
Jennifer
J
Gingis
Leila
L
Crone
Nathan E
NE
D000328:Adult; D001931:Brain Mapping / Q000379:methods*; D002540:Cerebral Cortex / Q000503:physiopathology* / Q000601:surgery; D004558:Electric Stimulation; D004567:Electrodes, Implanted; D004827:Epilepsy / Q000175:diagnosis / Q000503:physiopathology* / Q000601:surgery; D005260:Female; D007839:Functional Laterality / Q000502:physiology; D006801:Humans; D008297:Male; D010296:Parietal Lobe / Q000503:physiopathology; D010468:Perceptual Disorders / Q000175:diagnosis* / Q000503:physiopathology; D011183:Postoperative Complications / Q000503:physiopathology; D011300:Preoperative Care; D013702:Temporal Lobe / Q000503:physiopathology