title: Toward the total synthesis of spirastrellolide A. Part 3: intelligence gathering and preparation of a ring-expanded analogue.
abstract: Different methods for the formation of the C.25-C.26 bond of spirastrellolide A () are evaluated that might qualify for the end game of the projected total synthesis, with emphasis on metathetic ways to forge the macrocyclic frame.
authors.affiliation: Max-Planck-Institut für Kohlenforschung, D-45470, Mülheim/Ruhr, Germany. fuerstner@mpi-muelheim.mpg.de
authors.forename: Alois
authors.initials: A
authors.lastname: Fürstner
authors.forename: Bernhard
authors.initials: B
authors.lastname: Fasching
authors.forename: Gregory W
authors.initials: GW
authors.lastname: O'Neil
authors.forename: Michaël D B
authors.initials: MD
authors.lastname: Fenster
authors.forename: Cédrickx
authors.initials: C
authors.lastname: Godbout
authors.forename: Julien
authors.initials: J
authors.lastname: Ceccon
mesh_terms: D003500:Cyclization; D007202:Indicators and Reagents / Q000737:chemistry; D018942:Macrolides / Q000138:chemical synthesis*; D013141:Spiro Compounds
chemical_list: D007202:Indicators and Reagents; D018942:Macrolides; D013141:Spiro Compounds; C475125:spirastrellolide A