title: Total hearing loss and blindness caused by relapsing polychondritis and myelodysplastic syndrome.
abstract: Relapsing polychondritis is an autoimmune disease that primarily manifests as cartilaginous tissue destruction. However, the immune impairment may also involve noncartilaginous tissues such as kidneys, blood vessels, etc. The disease may occur as a primary disorder or in association with other diseases. The case of a female patient with concurrent manifestation of myelodysplastic syndrome-refractory anemia with excess blasts, and relapsing polychondritis, is presented. The diagnosis of relapsing polychondritis was established ten months after the diagnosis of myelodysplastic syndrome, when the criteria for the former were met. Total hearing loss and blindness developed soon thereafter.
authors.affiliation: General Hospital Dr. Josip Bencevic, Andrije Stampara 42, 35000, Slavonski Brod, Croatia. bozena.coha@sb.htnet.hr
authors.forename: Bozena
authors.initials: B
authors.lastname: Coha
authors.forename: Ljubica
authors.initials: L
authors.lastname: Fustar-Preradovic
authors.forename: Sandra
authors.initials: S
authors.lastname: Sekelj
authors.forename: Alen
authors.initials: A
authors.lastname: Sekelj
mesh_terms: D001766:Blindness / Q000209:etiology*; D003638:Deafness / Q000209:etiology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D009190:Myelodysplastic Syndromes / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D011081:Polychondritis, Relapsing / Q000150:complications* / Q000175:diagnosis / Q000628:therapy