A functional proteomic strategy to discover inhibitors for uncharacterized hydrolases.
Li
Weiwei
W
The Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, USA.
Blankman
Jacqueline L
JL
Cravatt
Benjamin F
BF
D000818:Animals; D019556:COS Cells; D002522:Chlorocebus aethiops; D004353:Drug Evaluation, Preclinical / Q000379:methods*; D004791:Enzyme Inhibitors / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D006867:Hydrolases / Q000037:antagonists & inhibitors* / Q000378:metabolism; D015394:Molecular Structure; D040901:Proteomics / Q000379:methods*
D004791:Enzyme Inhibitors; D006867:Hydrolases