O-aryloxycarbonyl hydroxamates: new beta-lactamase inhibitors that cross-link the active site.
Wyrembak
Pauline N
PN
Department of Chemistry, Wesleyan University, Middletown, Connecticut 06459, USA.
Babaoglu
Kerim
K
Pelto
Ryan B
RB
Shoichet
Brian K
BK
Pratt
R F
RF
D001665:Binding Sites; D003432:Cross-Linking Reagents / Q000737:chemistry*; D018360:Crystallography, X-Ray; D016972:Enterobacter cloacae / Q000201:enzymology; D004791:Enzyme Inhibitors / Q000737:chemistry* / Q000494:pharmacology*; D006877:Hydroxamic Acids / Q000737:chemistry*; D008958:Models, Molecular; D015394:Molecular Structure; D065093:beta-Lactamase Inhibitors; D001618:beta-Lactamases / Q000737:chemistry* / Q000378:metabolism
D003432:Cross-Linking Reagents; D004791:Enzyme Inhibitors; D006877:Hydroxamic Acids; D065093:beta-Lactamase Inhibitors; D001618:beta-Lactamases