title: Hoarseness and misdirected swallowing in patients with hiatal hernia.
abstract: The purpose of this study was to elucidate whether misdirected swallowing is an extra-laryngeal cause of hoarseness and investigate whether the prevalence of misdirected swallowing and hoarseness in patients with hiatal hernias differ from those with and without pathological gastroesophageal reflux (GER). One hundred and ninety eight patients with hiatal hernias diagnosed via esophageal manometry and pH-reflux test and 262 subjects in the general population who did not have a hiatal hernia at endoscopy, filled in a questionnaire about symptoms on hoarseness, misdirected swallowing, and heartburn. Hoarseness (35%), misdirected swallowing to the larynx (MSL; 35%), misdirected swallowing to the nose (MSN; 22%) and heartburn (85%) were significantly more common in patients with hiatal hernia than in controls (13, 5, 1, and 6%, respectively, P<0.001). MSL and MSN in the patient group were significantly interrelated (P<0.0001). Hoarseness and MSL were not significantly associated (P<0.076). Hoarseness and MSL were as common in the hernia group with normal GER, as in the group with pathological GER. There is a predisposition for hoarseness and MSL in patients with hiatal hernias, but the cause-and-effect relationship is unclear. Hoarseness does not seem to be caused by pathological GER.
authors.affiliation: Department of Otorhinolaryngology, University Hospital, Linköping, Sweden.
authors.forename: Anna-Britta
authors.initials: AB
authors.lastname: Mjönes
authors.forename: Kurt
authors.initials: K
authors.lastname: Borch
authors.forename: Lita
authors.initials: L
authors.lastname: Tibbling
authors.forename: Torbjörn
authors.initials: T
authors.lastname: Ledin
authors.forename: Elisabeth
authors.initials: E
authors.lastname: Hultcrantz
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016022:Case-Control Studies; D003680:Deglutition Disorders / Q000453:epidemiology* / Q000473:pathology; D005260:Female; D005764:Gastroesophageal Reflux / Q000150:complications* / Q000473:pathology; D006551:Hernia, Hiatal / Q000150:complications* / Q000473:pathology; D006685:Hoarseness / Q000453:epidemiology* / Q000473:pathology; D006801:Humans; D007830:Larynx; D008297:Male; D008875:Middle Aged; D009666:Nose; D015995:Prevalence