Actin-related proteins in chromatin-level control of the cell cycle and developmental transitions.
Regulating developmental transitions, cell proliferation and cell death through differential gene expression is essential to the ontogeny of all multicellular organisms. Chromatin remodeling is an active process that is necessary for managing the genome-wide suppression of gene activities resulting from DNA compaction. Recent data in plants suggest a general theme, whereby chromatin remodeling complexes containing nuclear actin-related proteins (ARPs) potentiate the activities of crucial regulatory genes involved in plant growth and development, in addition to their basal activities on a much larger set of genes.
Meagher
Richard B
RB
Department of Genetics, University of Georgia, Athens, GA 30602, USA. meagher@uga.edu <meagher@uga.edu>
Kandasamy
Muthugapatti K
MK
Deal
Roger B
RB
McKinney
Elizabeth C
EC
D000199:Actins / Q000737:chemistry* / Q000378:metabolism; D029681:Arabidopsis Proteins / Q000378:metabolism; D002453:Cell Cycle; D002467:Cell Nucleus / Q000378:metabolism; D049109:Cell Proliferation; D002843:Chromatin / Q000737:chemistry* / Q000378:metabolism*; D004247:DNA / Q000737:chemistry*; D018506:Gene Expression Regulation, Plant; D016678:Genome; D008840:Microfilament Proteins / Q000378:metabolism; D008954:Models, Biological; D018515:Plant Leaves; D018521:Plant Physiological Phenomena; D010940:Plant Proteins / Q000378:metabolism
C507995:ARP6 protein, Arabidopsis; C477328:ATARP4 protein, Arabidopsis; C477329:ATARP7 protein, Arabidopsis; D000199:Actins; D029681:Arabidopsis Proteins; D002843:Chromatin; D008840:Microfilament Proteins; D010940:Plant Proteins; D004247:DNA