[Effects of Guben Yiliu II combined with arterial perfusion with chemotherapeutic agent in treating advanced pancreatic cancer].
OBJECTIVE
To observe the effects ot Guben Yiliu II (GY II) combined with arterial perfusion with chemotherapeutic agent on advanced pancreatic cancer (APC).


METHODS
Sixty-five APC patients were randomly assigned to the treated group (35 cases) given GY II and arterial perfusion with chemotherapeutic agent and the control group (30 cases) with chemotherapeutic agent alone.


RESULTS
The clinical beneficial rate was 54.2% in the treated group and 40.0% in the control group, with significant difference between them (P < 0.05), the overall effective rate being 17.1% and 13.3%, and the effective rate in relieving pain being 64.5% and 59.2% in the treated and the control group respectively, all showed insignificant difference between groups (P > 0.05). Furthermore, in the treated group after treatment, the blood hypercoagulation state ameliorated, cellular immunity elevated, the toxic and side- effects of chemical medicine relieved, and the quality of life improved.


CONCLUSIONS
GY II is effective in enhancing clinical effects and relieving toxic and side-effects of chemotherapy, and so, better efficacy could be obtained by therapy of GY II and arterial perfusion with chemotherapeutic agent for treatment of APC.
Zhang
Qing
Q
Department of Tumor, Beijing Hospital of TCM, Capital Medical University, Beijing. zhangqingys@yahoo.com.cn
Wang
Xiao-Min
XM
Chi
Hui-Chang
HC
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007261:Infusions, Intra-Arterial; D008297:Male; D008875:Middle Aged; D010190:Pancreatic Neoplasms / Q000188:drug therapy* / Q000473:pathology; D008517:Phytotherapy; D016896:Treatment Outcome
D004365:Drugs, Chinese Herbal; C533620:guben yiliu II