Successful pregnancy in renal transplant recipient with previous known polyomavirus nephropathy.
Pregnancy after renal transplantation has become increasingly common. Studies in non-immunocompromised patients have shown that pregnant women have increased susceptibility to infection or reactivation of latent virus such as BK virus. To what extent a renal transplant recipient is at risk for reactivation of polyoma virus during pregnancy remains unknown. We hereby report successful pregnancy outcome in a renal transplant recipient with a known history of BK virus nephropathy treated with cidofovir i.v. To our knowledge, this is the first published experience with a successful pregnancy in renal transplant recipients with known history of polyomavirus-associated nephropathy.
Midtvedt
Karsten
K
Department of Nephrology, Rikshospitalet-Radiumhospitalet Medical Centre, Oslo, Norway. karsten.midvedt@rikshospitalet.no
Bjorang
Ola
O
Letting
Anne-Sofie
AS
D000328:Adult; D000998:Antiviral Agents / Q000627:therapeutic use*; D001739:BK Virus / Q000302:isolation & purification*; D000077404:Cidofovir; D003596:Cytosine / Q000031:analogs & derivatives* / Q000627:therapeutic use; D005260:Female; D006085:Graft Survival; D006801:Humans; D007674:Kidney Diseases / Q000601:surgery; D016030:Kidney Transplantation; D009393:Nephritis / Q000175:diagnosis / Q000188:drug therapy / Q000821:virology; D063065:Organophosphonates / Q000627:therapeutic use*; D027601:Polyomavirus Infections / Q000175:diagnosis / Q000188:drug therapy* / Q000821:virology; D011247:Pregnancy; D011256:Pregnancy Outcome; D014412:Tumor Virus Infections / Q000175:diagnosis / Q000188:drug therapy* / Q000821:virology
D000998:Antiviral Agents; D063065:Organophosphonates; D003596:Cytosine; D000077404:Cidofovir