Stereochemistry of enacyloxins. Part 4: Complete structural and configurational assignment of the enacyloxin family, a series of antibiotics from Frateuria sp. W-315.
The absolute configurations of the enacyloxins, a series of polyhydroxylated polyene antibiotics from Frateuria species, were determined. The so far elusive (13'R,14'R,15'S)-configuration was assigned to enacycloxin IVa (1) by means of 'J-resolved HMBC-1' and NOESY NMR methods.
Furukawa
Hiroyuki
H
Laboratory of Applied Bioorganic Chemistry, Division of Life Science, Graduate School of Agricultural Science, Tohoku University, 1-1 Tsutsumidori-Amamiya, Aoba-ku, Sendai 981-8555, Japan.
Kiyota
Hiromasa
H
Yamada
Teiko
T
Yaosaka
Manabu
M
Takeuchi
Ryo
R
Watanabe
Toshihiko
T
Kuwahara
Shigefumi
S
D016947:Acetobacteraceae / Q000737:chemistry*; D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000302:isolation & purification; D008968:Molecular Conformation; D009492:Neurospora crassa / Q000737:chemistry; D011090:Polyenes / Q000737:chemistry* / Q000302:isolation & purification
D000900:Anti-Bacterial Agents; D011090:Polyenes