title: Ovarian ossification associated with endometriosis.
abstract: BACKGROUND
  Bone formation in the ovary, with the exception of developing in the setting of mature cystic teratoma, is exceedingly rare.
  
  
  METHODS
  A 46-year-old woman with a history of endometriosis and chronic pelvic pain underwent total abdominal hysterectomy and bilateral salpingo-oophorectomy. A 3 cm solid heavily calcified mass with a stony hard consistency was detected within the right ovary. Microscopic examination revealed extensive calcification of the right ovarian stroma with formation of abundant mature bone, adjacent to small foci of endometriosis.
  
  
  CONCLUSIONS
  Endometriosis can be associated with ovarian ossification, forming an extensively calcified adnexal mass. Conservative treatment with close follow-up may be adequate in patients with a history of endometriosis who present with a small heavily calcified ovarian mass and wish to preserve their fertility.
authors.affiliation: Department of Pathology, Soroka University Medical Center and Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
authors.forename: R
authors.initials: R
authors.lastname: Shaco-Levy
authors.forename: T
authors.initials: T
authors.lastname: Lazer
authors.forename: B
authors.initials: B
authors.lastname: Piura
authors.forename: A
authors.initials: A
authors.lastname: Wiznitzer
mesh_terms: D002114:Calcinosis / Q000209:etiology*; D004715:Endometriosis / Q000150:complications* / Q000601:surgery; D005260:Female; D013509:Gynecologic Surgical Procedures; D006801:Humans; D008875:Middle Aged; D009999:Ossification, Heterotopic / Q000209:etiology*; D010049:Ovarian Diseases / Q000209:etiology* / Q000473:pathology / Q000601:surgery