Persistence of West Nile virus-specific antibodies in viremic blood donors.
We evaluated West Nile virus (WNV) antibody persistence by using follow-up plasma samples from 35 blood donors who made viremic donations in 2005. At 26 to 34 days of follow-up, all of the donors (n = 33) were positive for WNV immunoglobulin M (IgM), IgA, and IgG. At 1-year of follow-up, 17% of the donors (n = 23) were positive for WNV IgM, 57% were positive for WNV IgA, and 100% were positive for WNV IgG.
Prince
Harry E
HE
Focus Diagnostics, Cypress, California, USA. hprince@focusdx.com
Tobler
Leslie H
LH
Yeh
Cindy
C
Gefter
Nelly
N
Custer
Brian
B
Busch
Michael P
MP
D000914:Antibodies, Viral / Q000097:blood* / Q000276:immunology*; D001782:Blood Donors; D004797:Enzyme-Linked Immunosorbent Assay / Q000379:methods; D006801:Humans; D007070:Immunoglobulin A / Q000097:blood / Q000276:immunology; D007074:Immunoglobulin G / Q000097:blood / Q000276:immunology; D007075:Immunoglobulin M / Q000097:blood / Q000276:immunology; D014901:West Nile Fever / Q000097:blood / Q000276:immunology* / Q000821:virology; D014902:West Nile virus / Q000276:immunology*
D000914:Antibodies, Viral; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M