title: The blood platelet proteome is changed in UREMIC patients.
abstract: Comparative analysis of the protein profile of blood platelets isolated from nondialyzed and hemodialyzed uremic patients and healthy controls has been performed. These preliminary results indicate markedly changed expression of several proteins in blood platelets from both groups of patients compared with controls, with dramatic changes in hemodialyzed patients in the over-expression of low molecular peptides with a very wide range of pI values.
authors.affiliation: Department of Biophysics, Institute of Materials Science, Technical University of Lodz, Poland. bogdan.walkowiak@csk.umed.lodz.pl
authors.forename: Bogdan
authors.initials: B
authors.lastname: Walkowiak
authors.forename: Marta
authors.initials: M
authors.lastname: Kaminska
authors.forename: Wiesława
authors.initials: W
authors.lastname: Okrój
authors.forename: Wojciech
authors.initials: W
authors.lastname: Tanski
authors.forename: Anna
authors.initials: A
authors.lastname: Sobol
authors.forename: Zbigniew
authors.initials: Z
authors.lastname: Zbróg
authors.forename: Iwona
authors.initials: I
authors.lastname: Przybyszewska-Doros
mesh_terms: D000328:Adult; D000368:Aged; D001792:Blood Platelets / Q000378:metabolism*; D005260:Female; D005786:Gene Expression Regulation; D006801:Humans; D007526:Isoelectric Point; D008297:Male; D008875:Middle Aged; D020543:Proteome / Q000032:analysis / Q000378:metabolism*; D006435:Renal Dialysis; D014511:Uremia / Q000378:metabolism* / Q000628:therapy
chemical_list: D020543:Proteome