Differential protein expression in the honey bee head after a bacterial challenge.
Insect immune proteins and peptides induced during bacterial infection are predominantly synthesized by the fat body or by haemocytes and released into the hemolymph. However, tissues other than the "immune-related" ones are thought to play a role in bacteria-induced responses. Here we report a proteomic study of honey bee heads designed to identify the proteins that are differentially expressed after bacterial challenge in a major body segment not directly involved in insect immunity. The list of identified proteins includes structural proteins, an olfactory protein, proteins involved in signal transduction, energy housekeeping, and stress responses, and also two major royal jelly proteins. This study revealed a number of bacteria-induced responses in insect head tissue directly related to typical functions of the head, such as exocrine secretion, memory, and senses in general.
Scharlaken
Bieke
B
Laboratory of Zoophysiology, Ghent University, Ghent, Belgium.
De Graaf
Dirk C
DC
Memmi
Samy
S
Devreese
Bart
B
Van Beeumen
Jozef
J
Jacobs
Frans J
FJ
D000255:Adenosine Triphosphate / Q000378:metabolism; D000818:Animals; D001516:Bees / Q000276:immunology / Q000378:metabolism*; D050260:Carbohydrate Metabolism / Q000276:immunology; D004926:Escherichia coli / Q000276:immunology; D005260:Female; D006257:Head; D019476:Insect Proteins / Q000276:immunology / Q000378:metabolism*; D050356:Lipid Metabolism / Q000276:immunology; D040901:Proteomics; D015398:Signal Transduction / Q000276:immunology; D012903:Smell / Q000276:immunology; D013312:Stress, Physiological / Q000276:immunology / Q000378:metabolism
D019476:Insect Proteins; D000255:Adenosine Triphosphate