title: Giant malignant phylloides tumor: case report.
abstract: The incidence of phylloides breast tumors is less than 1% in the population affected by breast cancers. The age at higher risk is between 35 and 45 years. These neoplasms are characterized by a proliferation of mesenchimal and epithelial cells. We present a rare case of giant malignant phylloides tumor (28 x 21 x 15 cm) with a complet substitution of the gland. The clinical presentation of phylloides tumors is heterogenous; the surgical treatment is a conservative one of the gland if the neoplastic lesion size is less than 5 cm with a free margin of 1 cm and a mastectomy if the diameter of lesion is more than 5 cm. Complementary therapies still remain controversial.
authors.affiliation: University of Parma, Department of General Surgery and Organ Transplantation, Italy.
authors.forename: M F
authors.initials: MF
authors.lastname: Arcuri
authors.forename: P
authors.initials: P
authors.lastname: Del Rio
authors.forename: E M
authors.initials: EM
authors.lastname: Martella
authors.forename: L
authors.initials: L
authors.lastname: Bezer
authors.forename: M
authors.initials: M
authors.lastname: Sianesi
mesh_terms: D001943:Breast Neoplasms / Q000473:pathology* / Q000601:surgery; D005260:Female; D006801:Humans; D008875:Middle Aged; D003557:Phyllodes Tumor / Q000473:pathology* / Q000601:surgery