Right atrial botryoid rhabdomyosarcoma in an adult patient with recurrent pleomorphic rhabdomyosarcomas following doxorubicin therapy.
We describe a case of a 37-year-old Hispanic woman who presented with a right atrial botryoid rhabdomyosarcoma 2 years after doxorubicin therapy for a recurrent pleomorphic rhabdomyosarcoma of the chest wall. Although this may be a second primary, it most likely represents a cardiac metastasis with maturation of chemotherapy-resistant tumor cells.
Scott
Rolf Sjuve
RS
Department of Pathology, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA.
Jagirdar
Jaishree
J
D000328:Adult; D000903:Antibiotics, Antineoplastic / Q000627:therapeutic use*; D017024:Chemotherapy, Adjuvant; D018572:Disease-Free Survival; D004317:Doxorubicin / Q000627:therapeutic use*; D005260:Female; D006325:Heart Atria / Q000473:pathology*; D006338:Heart Neoplasms / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008279:Magnetic Resonance Imaging; D009364:Neoplasm Recurrence, Local; D018233:Rhabdomyosarcoma, Embryonal / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D013909:Thorax / Q000473:pathology
D000903:Antibiotics, Antineoplastic; D004317:Doxorubicin