[Fluorescence cytology. Improvement of urinary cytology].
Urothelial cancer of the bladder is a frequent disease, and urinary cytology often is used as a routine diagnostic tool. But this technique has an impaired sensitivity in low-grade tumours, and as a subjective method it is highly dependent on the experience of the cytologist. Here we present the technique of fluorescence cytology as an improvement of conventional cytology. This method is potentially able to compensate for the disadvantages of urinary cytology as it is an automated process that uses the principles of 5-Ala-induced photodynamic diagnosis (PDD).
Tritschler
S
S
Urologische Klinik und Poliklink, Klinikum Grosshadern, Ludwig-Maximilians-Universität, Marchioninistrasse 15, 81377 München. Stefan.Tritschler@med.uni-muenchen.de
Tauber
S
S
Meier
R
R
Stepp
H
H
Karl
A
A
Zaak
D
D
Stief
C G
CG
D000622:Aminolevulinic Acid; D002295:Carcinoma, Transitional Cell / Q000175:diagnosis / Q000473:pathology*; D002469:Cell Separation / Q000379:methods*; D005260:Female; D005434:Flow Cytometry / Q000379:methods*; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008297:Male; D008856:Microscopy, Fluorescence / Q000379:methods*; D017319:Photosensitizing Agents; D013050:Spectrometry, Fluorescence / Q000379:methods*; D001743:Urinary Bladder / Q000473:pathology; D001749:Urinary Bladder Neoplasms / Q000175:diagnosis / Q000473:pathology*; D014556:Urine / Q000166:cytology*
D017319:Photosensitizing Agents; D000622:Aminolevulinic Acid