Adrenocorticotropin-secreting pancreatoblastoma.
We present a 3-year-old child with Cushing's syndrome due to an ACTH-secreting metastatic pancreatoblastoma. This malignancy is a rare cause of Cushing's syndrome, particularly at pediatric age. We describe her course including the use of ketoconazole to alleviate hypercortisolemia.
Kletter
Gad B
GB
Pediatric Endocrine, Swedish Physician Division 1101 Madison, Suite # 800, Seattle, WA 98104, USA. gad.kletter@swedish.org
Sweetser
David A
DA
Wallace
Steven F
SF
Sawin
Robert S
RS
Rutledge
Joe C
JC
Geyer
J Russell
JR
D000182:ACTH Syndrome, Ectopic / Q000175:diagnosis*; D000324:Adrenocorticotropic Hormone / Q000378:metabolism*; D002675:Child, Preschool; D003480:Cushing Syndrome / Q000175:diagnosis*; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D018193:Neoplasms, Complex and Mixed / Q000175:diagnosis / Q000378:metabolism* / Q000473:pathology; D010190:Pancreatic Neoplasms / Q000175:diagnosis / Q000378:metabolism* / Q000473:pathology
D000324:Adrenocorticotropic Hormone