title: Intracerebral Hodgkin's lymphoma in a patient with human immunodeficiency virus.
abstract: Central nervous system (CNS) involvement by Hodgkin Lymphoma (HL) is rarely reported. Retrospective and prospective cohort studies suggest an incidence of 0.2-0.5%, mostly in relapsed disease. In spite of a 3 to 18-fold increased risk of HL in patients with human immunodeficiency virus (HIV), only two cases have been reported so far. In this paper, we now report a third case of HIV patient with HL who progressed with isolated CNS infiltration after a standard chemotherapy induced clinical remission. In 1991, when the first case of intracerebral involvement in HIV+ HL was reported an increase of this type of cases would have been expected, but only one more case has been reported since then.
authors.affiliation: Department of Hematology, La Princesa Hospital, Spain.
authors.forename: A
authors.initials: A
authors.lastname: García-Noblejas
authors.forename: S
authors.initials: S
authors.lastname: Nieto
authors.forename: R
authors.initials: R
authors.lastname: Liberal
authors.forename: J
authors.initials: J
authors.lastname: Cannata
authors.forename: J L
authors.initials: JL
authors.lastname: Steegmann
authors.forename: J M
authors.initials: JM
authors.lastname: Fernàndez-Rañada
authors.forename: R
authors.initials: R
authors.lastname: Arranz
mesh_terms: D000328:Adult; D001932:Brain Neoplasms / Q000150:complications / Q000473:pathology*; D006678:HIV; D015658:HIV Infections / Q000150:complications / Q000473:pathology*; D006689:Hodgkin Disease / Q000150:complications / Q000473:pathology*; D006801:Humans; D008297:Male