title: A twelve-week randomized controlled study of the cognitive-behavioral Integrated Psychological Therapy program: positive effect on the social functioning of schizophrenic patients.
abstract: OBJECTIVE
  The present study was designed to evaluate the effect of twelve weekly sessions of the cognitive-behavioral program originally known as the Integriertes Psychologisches Therapieprogramm für Schizophrene Patienten, designated the Integrated Psychological Therapy (IPT) program in English, on cognition, social adjustment and quality of life in schizophrenic outpatients, comparing it to the effect of treating such patients as usual.
  
  
  METHODS
  Fifty-six adult outpatients (from 18 to 65 years of age) with ICD-10-based diagnoses of schizophrenia were randomly assigned to two different groups: active intervention (IPT group); and treatment as usual (control group). Outcome measures were quality of life (as determined using the WHOQOL-Bref), cognition (Mini-Mental State Examination and Word Recall Test), global functioning (DSM-IV Global Assessment of Functioning Scale), social functioning (Social and Occupational Functioning Assessment Scale) and social adjustment (Social Adjustment Scale).
  
  
  RESULTS
  The findings suggest that, in comparison with treatment as usual (control group), the twelve-session IPT program had a positive effect on several outcome measures: cognition in the domains of spatiotemporal orientation (p = 0.051) and memory (p = 0.031); overall social adjustment (p = 0.037), leisure/social life (p = 0.051) and family relations (p = 0.008); overall functioning (p = 0.000); social-occupational functioning (p = 0.000); and quality of life in the psychological domain (p = 0.021).
  
  
  CONCLUSIONS
  The twelve-session cognitive-behavioral IPT intervention demonstrated superiority over treatment as usual in its effects on cognition, social adjustment and quality of life. Studies involving larger samples, longer follow-up periods and additional outcome measures are needed in order to assess the specific effects on dimensions of social functioning, cognitive functioning and quality of life in patients with schizophrenia.
authors.affiliation: Social Psychiatry, Schizophrenia Program, Hospital de Clínicas de Porto Alegre (HCPA), Porto Alegre (RS), Brazil. marilenezimmer@gmail.com
authors.forename: Marilene
authors.initials: M
authors.lastname: Zimmer
authors.forename: Adriana Veríssimo
authors.initials: AV
authors.lastname: Duncan
authors.forename: Daniela
authors.initials: D
authors.lastname: Laitano
authors.forename: Eloisa Elena
authors.initials: EE
authors.lastname: Ferreira
authors.forename: Paulo
authors.initials: P
authors.lastname: Belmonte-de-Abreu
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D015928:Cognitive Behavioral Therapy / Q000379:methods*; D019033:Delivery of Health Care, Integrated; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011569:Psychiatric Status Rating Scales; D011615:Psychotherapy, Group / Q000379:methods; D011788:Quality of Life; D012559:Schizophrenia / Q000534:rehabilitation / Q000628:therapy*; D012565:Schizophrenic Psychology; D012917:Social Adjustment; D012959:Socioeconomic Factors; D016896:Treatment Outcome