title: Lung nodule detection via Bayesian voxel labeling.
abstract: This paper describes a system for detecting pulmonary nodules in CT images. It aims to label individual image voxels in accordance to one of a number of anatomical (pulmonary vessels or junctions), pathological (nodules), or spurious (noise) events. The approach is orthodoxly Bayesian, with particular care taken in the objective establishment of prior probabilities and the incorporation of relevant medical knowledge. We provide, under explicit modeling assumptions, closed-form expressions for all the probability distributions involved. The technique is applied to real data, and we present a discussion of its performance.
authors.affiliation: GE Global Research, One Research Circle, Niskayuna, NY 12309, USA.
authors.forename: Paulo R S
authors.initials: PR
authors.lastname: Mendonça
authors.forename: Rahul
authors.initials: R
authors.lastname: Bhotika
authors.forename: Fei
authors.initials: F
authors.lastname: Zhao
authors.forename: James V
authors.initials: JV
authors.lastname: Miller
mesh_terms: D000465:Algorithms; D001185:Artificial Intelligence; D001499:Bayes Theorem; D003198:Computer Simulation; D006801:Humans; D021621:Imaging, Three-Dimensional / Q000379:methods*; D016247:Information Storage and Retrieval / Q000379:methods*; D008175:Lung Neoplasms / Q000000981:diagnostic imaging; D008954:Models, Biological; D015233:Models, Statistical; D010363:Pattern Recognition, Automated / Q000379:methods*; D011856:Radiographic Image Enhancement / Q000379:methods; D011857:Radiographic Image Interpretation, Computer-Assisted / Q000379:methods*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D003074:Solitary Pulmonary Nodule / Q000000981:diagnostic imaging*; D013382:Subtraction Technique; D014057:Tomography, X-Ray Computed / Q000379:methods*