title: [Selection and use of anti-infective agents for intra-abdominal infections].
abstract: BACKGROUND
  Intra-abdominal infections are common and are associated with elevated morbidity and mortality. The microorganisms that cause intra-abdominal infections are usually from the gastrointestinal flora, mainly E. coli and Bacteroides fragilis.
  
  
  OBJECTIVE
  To present a review of the selection and use of antibiotics in intra-abdominal infections.
  
  
  CONCLUSIONS
  Appropriate use of antibiotics is essential to control infection and to reduce treatment failure. Antibiotics are initiated whenever intra-abdominal infection is suspected and the antimicrobial agents are selected based on the most common microorganisms involved. In addition, efficacy, cost, safety, and posologic regimen are considered for an appropriated selection. Antibiotic regimen is different whether the infection is acquired in the community or at hospital due to the more resistant flora in the latter.
authors.affiliation: Serviço de Cirurgia do Aparelho Digestivo, Hospital de Clínicas, Universidade Federal do Paraná, Curitiba, PR. juliocoelho@bbs2.sul.com.br
authors.forename: Júlio Cezar Uili
authors.initials: JC
authors.lastname: Coelho
authors.forename: Giorgio Alfredo Pedroso
authors.initials: GA
authors.lastname: Baretta
authors.forename: Luciano
authors.initials: L
authors.lastname: Okawa
mesh_terms: D034841:Abdominal Cavity / Q000382:microbiology; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D001424:Bacterial Infections / Q000188:drug therapy* / Q000382:microbiology; D003428:Cross Infection / Q000188:drug therapy* / Q000382:microbiology; D004066:Digestive System Diseases / Q000188:drug therapy* / Q000382:microbiology; D006801:Humans; D012720:Severity of Illness Index; D013530:Surgical Wound Infection / Q000188:drug therapy* / Q000382:microbiology
chemical_list: D000900:Anti-Bacterial Agents