title: Useful optical density range in film dosimetry: limitations due to noise and saturation.
abstract: The optical density (OD) range for the scanners used in film dosimetry is limited due to saturation and noise. As the OD increases, saturation causes the rate of change of the output with respect to the input to become smaller, while at the same time noise remains fairly constant or increases. The combined effect leads to a degradation of the signal-to-noise ratio (SNR) at high optical densities. In this study, the uncertainty in the OD measurement, d(m), is expressed as a function of the optical density d. The functional relationship obtained gives the amplitude w of an interval around d in which d(m) will be found with a given probability p. The relationship w = w(d, p) is later used to determine which OD ranges fulfil a set of requirements on w and p. As an application of the procedure, the noise and saturation characteristics of a commercial film digitizer system are measured. Their contribution to the uncertainties of the dosimetric procedure is reported, and the data are used to provide an optical density range for a given uncertainty and confidence level associated with the digitizer. These data can be further combined with the data from other sources of noise such as film noise in order to estimate the final uncertainty of the dosimetric process.
authors.affiliation: Servicio de Radiofísica y Protección Radiológica, Hospital Universitario Virgen de la Arrixaca, Ctra. Madrid-Cartagena S/N, E-30120 El Palmar (Murcia), Spain. antonio.gonzalez7@carm.es
authors.forename: Antonio
authors.initials: A
authors.lastname: González-López
mesh_terms: D016477:Artifacts; D003198:Computer Simulation; D005373:Film Dosimetry / Q000295:instrumentation* / Q000379:methods*; D015233:Models, Statistical; D055095:Optics and Photonics / Q000295:instrumentation*; D010783:Photometry / Q000295:instrumentation* / Q000379:methods*; D011829:Radiation Dosage; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity