title: N2-benzyloxycarbonylguan-9-yl acetic acid derivatives as HIV-1 reverse transcriptase non-nucleoside inhibitors with decreased loss of potency against common drug-resistance mutations.
authors.affiliation: Chemistry Department, School of Engineering & Physical Sciences, Heriot-Watt University, William H. Perkin Building, Riccarton, Edinburgh EH14 4AS, UK.
authors.forename: Kassim F
authors.initials: KF
authors.lastname: Adebambo
authors.forename: Samantha
authors.initials: S
authors.lastname: Zanoli
authors.forename: Michael G
authors.initials: MG
authors.lastname: Thomas
authors.forename: Reynel
authors.initials: R
authors.lastname: Cancio
authors.forename: Nicola M
authors.initials: NM
authors.lastname: Howarth
authors.forename: Giovanni
authors.initials: G
authors.lastname: Maga
mesh_terms: D000085:Acetates / Q000737:chemistry / Q000494:pharmacology*; D024882:Drug Resistance, Viral / Q000235:genetics*; D006147:Guanine / Q000031:analogs & derivatives* / Q000737:chemistry / Q000494:pharmacology; D054303:HIV Reverse Transcriptase / Q000037:antagonists & inhibitors*; D015497:HIV-1 / Q000187:drug effects* / Q000235:genetics; D007700:Kinetics; D018894:Reverse Transcriptase Inhibitors / Q000737:chemistry / Q000494:pharmacology*
chemical_list: D000085:Acetates; D018894:Reverse Transcriptase Inhibitors; D006147:Guanine; C514824:reverse transcriptase, Human immunodeficiency virus 1; D054303:HIV Reverse Transcriptase