title: Total synthesis and absolute configuration determination of (+)-bruguierol C.
abstract: The first total synthesis and absolute configuration of bruguierol C are reported. The key step involved the diastereoselective capture of an in situ generated oxocarbenium ion via an intramolecular Friedel-Crafts alkylation.
authors.affiliation: Department of Chemistry, 500 Campus Drive, The University of Alabama, Tuscaloosa, Alabama 35487-0336, USA.
authors.forename: Dionicio Martinez
authors.initials: DM
authors.lastname: Solorio
authors.forename: Michael P
authors.initials: MP
authors.lastname: Jennings
mesh_terms: D006575:Heterocyclic Compounds, 3-Ring / Q000138:chemical synthesis / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D021241:Spectrometry, Mass, Electrospray Ionization; D013055:Spectrophotometry, Infrared; D013237:Stereoisomerism
chemical_list: D006575:Heterocyclic Compounds, 3-Ring; C523709:bruguierol C