title: Chemical composition and antimicrobial activity of the essential oil of Teucrium ramosissimum (Lamiaceae).
abstract: The phytochemical composition of the essential oil of Teucrium ramosissimum (aerial parts), harvested in a mountainous region of Tunisia, was analyzed. A total of 68 compounds, accounting for 99.44% of the essential oil, were identified by GC and GC/MS. The major compounds were beta-eudesmol (61; 44.52%), caryophyllene oxide (56; 9.35%), alpha-thujene (1; 5.51%), sabinene (4; 4.71%), and T-cadinol (59; 3.9%). The essential oil, which is being used in Tunisian folk medicine against infectious diseases, was tested for its antimicrobial properties against five different bacteria, and found to have weak to moderate activity, with minimal-inhibitory-concentration (MIC) and minimal-bactericidal-concentration (MBC) values in the range 0.24-0.36 and 1.3-2.9 mg/ml, resp.
authors.affiliation: Unity of Pharmacognosy/Molecular Biology 99/UR/07-03, Faculty of Pharmacy, Rue Avicenne, Monastir, 5000, Tunisia.
authors.forename: Mohamed
authors.initials: M
authors.lastname: Ben Sghaier
authors.forename: Imed
authors.initials: I
authors.lastname: Chraief
authors.forename: Ines
authors.initials: I
authors.lastname: Skandrani
authors.forename: Ines
authors.initials: I
authors.lastname: Bouhlel
authors.forename: Jihed
authors.initials: J
authors.lastname: Boubaker
authors.forename: Soumaya
authors.initials: S
authors.lastname: Kilani
authors.forename: Aïcha
authors.initials: A
authors.lastname: Neffati
authors.forename: Amor
authors.initials: A
authors.lastname: Mahmoud
authors.forename: Mohamed
authors.initials: M
authors.lastname: Hammami
authors.forename: Leila
authors.initials: L
authors.lastname: Chekir-Ghedira
authors.forename: Kamel
authors.initials: K
authors.lastname: Ghedira
mesh_terms: D000890:Anti-Infective Agents / Q000737:chemistry* / Q000302:isolation & purification; D008826:Microbial Sensitivity Tests / Q000379:methods; D009822:Oils, Volatile / Q000737:chemistry* / Q000302:isolation & purification; D010936:Plant Extracts / Q000737:chemistry / Q000302:isolation & purification; D018515:Plant Leaves / Q000737:chemistry; D010938:Plant Oils / Q000737:chemistry* / Q000302:isolation & purification; D031367:Teucrium / Q000737:chemistry*
chemical_list: D000890:Anti-Infective Agents; D009822:Oils, Volatile; D010936:Plant Extracts; D010938:Plant Oils