title: [Chronic renal failure and transplantation].
abstract: Kidney transplantation is the best option for all patients with terminal renal failure. Kidney transplantation is not only associated with an improved quality of life in comparison to all other renal replacement therapies, this method also offers a significantly extended lifespan. Therefore, the option for transplantation has to be verified for every patient with renal failure. Graft and patient survival is best when transplantation is carried out just before starting dialysis treatment. Realistically, only living donor transplantation offers the option of sparing the recipient a long waiting period on dialysis. Although transplantation from living donors is superior to cadaveric kidney transplantation, a small risk remains for the donor. Kidney transplantation and the immunosuppressive therapy are associated with an increased risk for certain types of infection, an increased tumour risk and an increased risk for cardiovascular complications. To address these problems, specific recommendations for patient surveillance have been provided by different transplantation societies.
authors.affiliation: Klinik für Nieren- und Hochdruckkrankheiten, Universitätsklinikum Schleswig-Holstein, Campus Kiel, Schittenhelmstrasse 12, 24105 Kiel. kunzendorf@nephro.uni-kiel.de
authors.forename: U
authors.initials: U
authors.lastname: Kunzendorf
authors.forename: L
authors.initials: L
authors.lastname: Renders
authors.forename: E
authors.initials: E
authors.lastname: Ziegler
mesh_terms: D006084:Graft Rejection / Q000188:drug therapy / Q000209:etiology; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects / Q000627:therapeutic use; D007676:Kidney Failure, Chronic / Q000601:surgery*; D007677:Kidney Function Tests; D016030:Kidney Transplantation; D019520:Living Donors; D009894:Opportunistic Infections / Q000209:etiology; D011183:Postoperative Complications / Q000209:etiology; D011788:Quality of Life; D017582:Renal Replacement Therapy; D009927:Tissue and Organ Procurement
chemical_list: D007166:Immunosuppressive Agents