title: [Observation on the change of anti-S. japonicum antibody level in population migrated from outside embankment to new town].
abstract: OBJECTIVE
  To detect the change of the anti-S. japonicum antibody level after people migrated from outside embankment to newly established town.
  
  
  METHODS
  Three pilot spots were established for the investigation: one spot that both inhabitancy and cultivation disuse (A), one spot that only inhabitancy disuse but farming continued (B) and the third one served as control (C). DIGFA and ELISA were used to detect the antibody level in the populations from 2002 to 2005.
  
  
  RESULTS
  The positive rate of anti-S. japonicum antibody declined significantly from 6.63% to 3.52% by DIGFA and from 7.26% to 3.71% by ELISA at spot A (chi2=5.2625, P<0.05; chi2=6.3296, P<0.05, respectively). There was no significant difference on the positive rate of antibody in spots B and C. The average A450 value of ELISA in the three spots was statistically analyzed by One-Way ANOVA. It was only in spot B that the average A450 value declined from 0.182 in 2003 to 0.147 in 2005 (P<0.01).
  
  
  CONCLUSIONS
  The anti-S. japonicum antibody level in human population has decreased at certain degree after they migrated from outside embankment to new town.
authors.affiliation: Institute of Parasitic Diseases, Zhejiang Academy of Medical Sciences, WHO Collaborating Center for Research on Helminthiasis, Hangzhou 310013, China. wenliyonghz@hotmail.com
authors.forename: Li-Yong
authors.initials: LY
authors.lastname: Wen
authors.forename: Shao-Hong
authors.initials: SH
authors.lastname: Lu
authors.forename: Jun-Hu
authors.initials: JH
authors.lastname: Chen
authors.forename: Jian-Feng
authors.initials: JF
authors.lastname: Zhang
authors.forename: Li-Ling
authors.initials: LL
authors.lastname: Yu
authors.forename: Jian-Zu
authors.initials: JZ
authors.lastname: Ding
authors.forename: Xiao-Lan
authors.initials: XL
authors.lastname: Yan
authors.forename: Li-Ying
authors.initials: LY
authors.lastname: Shen
authors.forename: Wei
authors.initials: W
authors.lastname: Zheng
authors.forename: Lu-Lu
authors.initials: LL
authors.lastname: Gao
authors.forename: Tian-Ping
authors.initials: TP
authors.lastname: Wang
authors.forename: Shi-Qing
authors.initials: SQ
authors.lastname: Zhang
authors.forename: Geng-Xin
authors.initials: GX
authors.lastname: Chen
authors.forename: Yun
authors.initials: Y
authors.lastname: Ye
authors.forename: Xiao-Nong
authors.initials: XN
authors.lastname: Zhou
authors.forename: Jiang
authors.initials: J
authors.lastname: Zheng
mesh_terms: D000818:Animals; D000909:Antibodies, Helminth / Q000097:blood*; D000947:Antigens, Helminth / Q000097:blood; D002681:China / Q000453:epidemiology; D004797:Enzyme-Linked Immunosorbent Assay; D006801:Humans; D011157:Population Dynamics; D012549:Schistosoma japonicum / Q000276:immunology*; D012554:Schistosomiasis japonica / Q000453:epidemiology* / Q000469:parasitology / Q000517:prevention & control; D014171:Transients and Migrants
chemical_list: D000909:Antibodies, Helminth; D000947:Antigens, Helminth