A preliminary test of the protective efficacy of permethrin-treated bed nets in an area of Anopheles gambiae metabolic resistance to pyrethroids in north Cameroon.
A trial of permethrin-treated nets (PTNs) versus untreated nets (UTNs) was conducted in Pitoa (north Cameroon), where the main malaria vectors, Anopheles gambiae s.l. and Anopheles arabiensis, show metabolic-based permethrin resistance. The deterrent effect of permethrin greatly reduced A. gambiae biting rate inside rooms where PTNs were installed. After 3 months of net use, malaria reinfection rate was significantly lower in children sleeping under a PTN, but no such effect was observed after 6 months. Parasitaemia was not significantly different between the two arms. These findings suggest good, although transitory, personal protection against malaria conferred by PTNs in an area of metabolic-based permethrin resistance.
Etang
Josiane
J
Organisation de Coordination pour la lutte contre les Endémies en Afrique Centrale (OCEAC), P.O. Box 288, Yaoundé, Cameroun. josyet@yahoo.fr
Chouaibou
Mouhamadou
M
Toto
Jean-Claude
JC
Faye
Ousmane
O
Manga
Lucien
L
Samè-Ekobo
Albert
A
Awono-Ambene
Parfait
P
Simard
Frédéric
F
D000818:Animals; D000852:Anopheles; D001512:Bedding and Linens; D002163:Cameroon; D006801:Humans; D007305:Insecticide Resistance; D007306:Insecticides; D008288:Malaria / Q000517:prevention & control*; D009032:Mosquito Control / Q000379:methods*; D026023:Permethrin; D011722:Pyrethrins
D007306:Insecticides; D011722:Pyrethrins; D026023:Permethrin