title: Catalytic stereoselective synthesis of highly substituted indanones via tandem Nazarov cyclization and electrophilic fluorination trapping.
abstract: A new catalytic stereoselective tandem transformation via Nazarov cyclization/electrophilic fluorination has been accomplished. This sequence is efficiently catalyzed by a Cu(II) complex to afford fluorine-containing 1-indanone derivatives with two new stereocenters with high diastereoselectivity (trans/cis up to 49/1). Three examples of catalytic enantioselective tandem transformation are presented.
authors.affiliation: Department of Chemistry, School of Science, Tianjin University, Tianjin 300072, China.
authors.forename: Jing
authors.initials: J
authors.lastname: Nie
authors.forename: Hong-Wei
authors.initials: HW
authors.lastname: Zhu
authors.forename: Han-Feng
authors.initials: HF
authors.lastname: Cui
authors.forename: Ming-Qing
authors.initials: MQ
authors.lastname: Hua
authors.forename: Jun-An
authors.initials: JA
authors.lastname: Ma