title: Beneficial effects of periodontal treatment on metabolic control of hypercholesterolemia.
abstract: BACKGROUND
  The authors aimed to evaluate whether local periodontal therapy may influence plasma lipid levels in patients with periodontitis.
  
  
  METHODS
  Fifty patients (31 females and 19 males, age 36-66 yr) were randomly assigned to the treatment and control groups. Lipid profile and dental variables were measured at baseline and at the end of the study in both groups.
  
  
  RESULTS
  In the third month, there was a significant decrease in total and low density lipoprotein (LDL) cholesterol levels of the treatment group compared with baseline values. Also, the reduction in bleeding on probing, pocket depth, attachment loss, plaque index and gingival index were statistically significant in the treatment group.
  
  
  CONCLUSIONS
  The present study indicates that periodontitis causes changes in total and LDL cholesterol levels and local periodontal treatment resulted in a significant decrease in these markers. These results suggest a potential effect of periodontitis-driven systemic inflammation on lipid metabolism.
authors.affiliation: Hacettepe University Faculty of Medicine, Department of Internal Medicine, Ankara, Turkey. irem8886@yahoo.com
authors.forename: S Gul
authors.initials: SG
authors.lastname: Oz
authors.forename: Ozlem
authors.initials: O
authors.lastname: Fentoglu
authors.forename: Alpaslan
authors.initials: A
authors.lastname: Kilicarslan
authors.forename: Gulay Sain
authors.initials: GS
authors.lastname: Guven
authors.forename: Mine Durusu
authors.initials: MD
authors.lastname: Tanrtover
authors.forename: Yasar
authors.initials: Y
authors.lastname: Aykac
authors.forename: Tumay
authors.initials: T
authors.lastname: Sozen
mesh_terms: D000328:Adult; D002318:Cardiovascular Diseases / Q000097:blood / Q000517:prevention & control; D002784:Cholesterol / Q000097:blood*; D005260:Female; D006801:Humans; D006937:Hypercholesterolemia / Q000150:complications / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D010518:Periodontitis / Q000097:blood* / Q000150:complications / Q000628:therapy*; D016745:Root Planing; D014280:Triglycerides / Q000097:blood*
chemical_list: D014280:Triglycerides; D002784:Cholesterol