title: Nineteen years of experience with autotransfusion for elective surgery in children: more troublesome than we expected.
abstract: BACKGROUND
  Under the rationale that children undergoing elective surgery are the best candidates for autologous blood donors because of their long life expectancy, aggressive donations of autologous blood, even from infants, have been reported. A number of problems are associated with the procedure, however, whereas the risks of homologous blood are very low.
  
  
  METHODS
  From 1987 through 2005, of 5792 patients referred to blood transfusion services at two Japanese university hospitals for autologous blood donations, 314 children younger than 16 years old served as subjects for assessment.
  
  
  RESULTS
  Of 314 children, 7 were not suitable as autologous donors. In most cases this was due to uncooperative behavior. Over a follow-up period of 19 years, the authors encountered 53 cases (17.3%) of donation-related problems, and this rate was higher than the 6 percent rate recorded for adult cases (316/5305). Nine children suffered crucial complications such as vasovagal reactions, and one 14-year-old boy required a vasopressor drug. Important findings were that 6 of these were first-time donors, and the amount of blood drawn was under 10 percent of their estimated blood volume.
  
  
  CONCLUSIONS
  Of 53 donation-related problems, 9 (17.0%) were accompanied by marked hypotension. Drawing autologous blood from children has become easier with advanced devices; however, lessening of anxiety and tension are essential for the safety of children's autologous blood donation programs. Aggressive donation should be avoided.
authors.affiliation: Department of Laboratory Medicine, Iwate Medical University, 19-1 Uchimaru, Morioka City, Iwate 020-8505, Japan. ttasaki@jikei.ac.jp
authors.forename: Tetsunori
authors.initials: T
authors.lastname: Tasaki
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Ohto
mesh_terms: D000293:Adolescent; D000328:Adult; D001804:Blood Transfusion, Autologous / Q000009:adverse effects*; D002648:Child; D017558:Elective Surgical Procedures / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008297:Male