title: [Study of substrate specificity of a new peptide substrate of endothelin converting enzyme].
abstract: The new fluorogenic hexapeptide substrate CMC-Ala-Gly-Gly-Trp-Phe-Arg was used as substrate for endothelin-converting enzyme (ECE), angiotensin-converting enzyme (ACE) and neutral endopeptidase (NEP). The specific inhibitors lisinopril (ACE) and thiorphan (NEP) were used for identification of these enzyme activities,
authors.forename: T A
authors.initials: TA
authors.lastname: Gureeva
authors.forename: E V
authors.initials: EV
authors.lastname: Kugaevskaia
authors.forename: V F
authors.initials: VF
authors.lastname: Pozdnev
authors.forename: V N
authors.initials: VN
authors.lastname: Prozorovskiĭ
authors.forename: Iu E
authors.initials: IuE
authors.lastname: Eliseeva
authors.forename: N I
authors.initials: NI
authors.lastname: Solov'eva
mesh_terms: D000806:Angiotensin-Converting Enzyme Inhibitors / Q000737:chemistry; D016282:Aspartic Acid Endopeptidases / Q000037:antagonists & inhibitors / Q000737:chemistry*; D000072396:Endothelin-Converting Enzymes; D006801:Humans; D017706:Lisinopril / Q000737:chemistry; D008666:Metalloendopeptidases / Q000037:antagonists & inhibitors / Q000737:chemistry*; D009842:Oligopeptides / Q000737:chemistry*; D007703:Peptidyl-Dipeptidase A / Q000737:chemistry*; D011480:Protease Inhibitors / Q000737:chemistry; D013379:Substrate Specificity; D015244:Thiorphan / Q000737:chemistry
chemical_list: D000806:Angiotensin-Converting Enzyme Inhibitors; D009842:Oligopeptides; D011480:Protease Inhibitors; D015244:Thiorphan; D017706:Lisinopril; D007703:Peptidyl-Dipeptidase A; D016282:Aspartic Acid Endopeptidases; D008666:Metalloendopeptidases; D000072396:Endothelin-Converting Enzymes