Synchronous sertoli cell and serous cystadenoma tumors of the ovaries with mixed epithelial and stromal tumor of the kidney: a case report.
We present a rare case of a 68-year-old postmenopausal woman with a mobile, hard, and painless pelvic abdominal mass that was palpated to the umbilical scar. Ultrasonography demonstrated a solid mass in the upper pole of the right kidney and a predominantly solid pelvic abdominal mass. Serum testosterone was 413 ng/dL. The patient underwent laparotomy on the renal tumor, which was thought to have a probable ovarian metastasis. Bilateral ovariectomy and right nephrectomy were performed. Immunohistochemical and histopathologic assessment identified a right ovarian Sertoli cell tumor, a left ovarian serous cystadenoma, and a mixed epithelial-stromal tumor in the kidney with positive hormonal receptor. Because our patient had an ovarian neoplasm producing steroids and a kidney tumor expressing hormonal receptors, the hypothesis of possible endocrine dependence in the pathogenesis of mixed epithelial stromal tumor is reinforced.
da Silva
Cléber Sérgio
CS
Discipline of Gynecology and Obstetrics, Research Institute of Oncology, Federal University of Triângulo Mineiro Uberaba, Minas Gerais, Brazil.
Adad
Sheila Jorge
SJ
Saldanha
João Cristiane
JC
Cançado
Cristiane Gobbo
CG
Bachi
Carlos
C
Murta
Eddie Fernando Candido
EF
D000368:Aged; D018293:Cystadenoma, Serous / Q000473:pathology*; D005260:Female; D006801:Humans; D018193:Neoplasms, Complex and Mixed / Q000473:pathology*; D009375:Neoplasms, Glandular and Epithelial / Q000473:pathology*; D010051:Ovarian Neoplasms / Q000473:pathology*; D012707:Sertoli Cell Tumor / Q000473:pathology*; D018312:Sex Cord-Gonadal Stromal Tumors / Q000473:pathology*