[Endoscopic surgery in occupation lesions of the skull base].
OBJECTIVE
To explore the application of endoscopic endonasal approach in surgery for occupation lesions of the skull base.


METHODS
Forty-two cases of skull base lesions treated by endoscopic endonasal surgery were analyzed retrospectively. There were 13 malignant tumors in anterior or middle cranial fossa, 8 chordoma, 5 invasive pituitary adenoma, 4 fibrous dysplasia of the sphenoid bone, 3 neurofibroma, 3 fibroangioma, 3 ossifying fibroma and 3 other lesions.


RESULTS
Lesions were removed completely in 36 patients, 2 of them were performed in two stages because of sever bleeding, and subtotally in 6 patients. The complications included 1 acroisa of right eye and 1 cerebrospinal fluid otorrhea. Follow-up ranged 6 to 81 months after the surgery. Five patents were lost of follow-up. Eight patients recurred and 6 patients died.


CONCLUSIONS
The endoscopic transnasal surgery is a safe, effective and minimally invasive approach to resect skull base lesions in condition of indications, surgeon's experience and the facilities.
Chen
Lei
L
Department of Otorhinolaryngology Head and Neck Surgery, General Hospital of Chinese People's Liberation Army, Beijing 100853, China. chenlei301@hotmail.com
Wang
Gang
G
Wang
Rong-Guang
RG
D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D004724:Endoscopy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D019060:Minimally Invasive Surgical Procedures; D009666:Nose / Q000601:surgery*; D012189:Retrospective Studies; D019292:Skull Base Neoplasms / Q000601:surgery*; D055815:Young Adult