title: A review of the efficacy and safety of devil's claw for pain associated with degenerative musculoskeletal diseases, rheumatoid, and osteoarthritis.
abstract: Harpagophytum procumbens, known as devil's claw, has been used traditionally for the treatment of pain, fevers, and dyspepsia. Recently, it has become popular for the treatment of rheumatoid and osteoarthritis. Studies have yet to establish a clear mechanism of action; however, current research is focusing on pro-inflammatory mediators as well as on potential antioxidant characteristics.
authors.affiliation: Department of Anesthesia, Memorial Hospital, York, PA 17403, USA. sd372@drexel.edu
authors.forename: Sallie Stoltz
authors.initials: SS
authors.lastname: Denner
mesh_terms: D000818:Animals; D000975:Antioxidants / Q000627:therapeutic use; D001172:Arthritis, Rheumatoid / Q000150:complications*; D002986:Clinical Trials as Topic; D000075202:Contraindications; D004353:Drug Evaluation, Preclinical; D004347:Drug Interactions; D019317:Evidence-Based Medicine; D031684:Harpagophytum / Q000009:adverse effects / Q000276:immunology; D006801:Humans; D010003:Osteoarthritis / Q000150:complications*; D010146:Pain / Q000175:diagnosis / Q000188:drug therapy* / Q000209:etiology; D008517:Phytotherapy / Q000009:adverse effects / Q000379:methods*; D012449:Safety; D016896:Treatment Outcome
chemical_list: D000975:Antioxidants