A concise total synthesis of melithiazole C.
A short and convergent synthesis of the myxobacterial antibiotic melithiazole C is described featuring a highly E-selective cross-metathesis as the key step.
Gebauer
Julian
J
Laboratoire de Chimie Organique, ESPCI, CNRS, 10 rue Vauquelin, F-75231 Paris Cedex 05, France.
Arseniyadis
Stellios
S
Cossy
Janine
J
D000179:Acrylates / Q000138:chemical synthesis*; D000900:Anti-Bacterial Agents / Q000138:chemical synthesis; D013237:Stereoisomerism; D013844:Thiazoles / Q000138:chemical synthesis*
D000179:Acrylates; D000900:Anti-Bacterial Agents; D013844:Thiazoles; C401244:melithiazol C