Workshop on imaging science development for cancer prevention and preemption.
The concept of intraepithelial neoplasm (IEN) as a near-obligate precursor of cancers has generated opportunities to examine drug or device intervention strategies that may reverse or retard the sometimes lengthy process of carcinogenesis. Chemopreventive agents with high therapeutic indices, well-monitored for efficacy and safety, are greatly needed, as is development of less invasive or minimally disruptive visualization and assessment methods to safely screen nominally healthy but at-risk patients, often for extended periods of time and at repeated intervals. Imaging devices, alone or in combination with anticancer drugs, may also provide novel interventions to treat or prevent precancer.
Kelloff
Gary J
GJ
NIH/NCI/DCTD, Cancer Imaging Program, Bethesda, MD, USA. kelloffg@mail.nih.gov
Sullivan
Daniel C
DC
Baker
Houston
H
Clarke
Lawrence P
LP
Nordstrom
Robert
R
Tatum
James L
JL
Dorfman
Gary S
GS
Jacobs
Paula
P
Berg
Christine D
CD
Pomper
Martin G
MG
Birrer
Michael J
MJ
Tempero
Margaret
M
Higley
Howard R
HR
Petty
Brenda Gumbs
BG
Sigman
Caroline C
CC
Maley
Carlo
C
Sharma
Prateek
P
Wax
Adam
A
Ginsberg
Gregory G
GG
Dannenberg
Andrew J
AJ
Hawk
Ernest T
ET
Messing
Edward M
EM
Grossman
H Barton
HB
Harisinghani
Mukesh
M
Bigio
Irving J
IJ
Griebel
Donna
D
Henson
Donald E
DE
Fabian
Carol J
CJ
Ferrara
Katherine
K
Fantini
Sergio
S
Schnall
Mitchell D
MD
Zujewski
Jo Anne
JA
Hayes
Wendy
W
Klein
Eric A
EA
DeMarzo
Angelo
A
Ocak
Iclal
I
Ketterling
Jeffrey A
JA
Tempany
Clare
C
Shtern
Faina
F
Parnes
Howard L
HL
Gomez
Jorge
J
Srivastava
Sudhir
S
Szabo
Eva
E
Lam
Stephen
S
Seibel
Eric J
EJ
Massion
Pierre
P
McLennan
Geoffrey
G
Cleary
Kevin
K
Suh
Robert
R
Burt
Randall W
RW
Pfeiffer
Ruth M
RM
Hoffman
John M
JM
Roy
Hemant K
HK
Wang
Thomas
T
Limburg
Paul J
PJ
El-Deiry
Wafik S
WS
Papadimitrakopoulou
Vali
V
Hittelman
Walter N
WN
MacAulay
Calum
C
Veltri
Robert W
RW
Solomon
Diane
D
Jeronimo
Jose
J
Richards-Kortum
Rebecca
R
Johnson
Karen A
KA
Viner
Jaye L
JL
Stratton
Steven P
SP
Rajadhyaksha
Milind
M
Dhawan
Atam
A
D003952:Diagnostic Imaging / Q000379:methods*; D006801:Humans; D007090:Image Interpretation, Computer-Assisted; D009369:Neoplasms / Q000175:diagnosis / Q000517:prevention & control*; D011230:Precancerous Conditions / Q000175:diagnosis / Q000517:prevention & control*