title: Effects of prebiotic oligosaccharides and trehalose on growth and production of bacteriocins by lactic acid bacteria.
abstract: OBJECTIVE
  To investigate the effects of two prebiotics and trehalose on the production of bacteriocins.
  
  
  RESULTS
  Four carbohydrates [dextrose, fructo-oligosaccharides (FOS), raffinose, and trehalose] were used as the sole carbon source in a simple broth. Five bacteriocin-producing strains of bacteria, including those producing nisin, enteriocin, and other bacteriocins, were used, and their inhibitory activities when grown on each carbohydrate were determined. The inhibitory activity assay was performed using the agar well diffusion method, and Lactobacillus sakei JCM 1,157(T) was used as the indicator strain. Effective enhancement of bacteriocin production was observed with FOS and trehalose incubation.
  
  
  CONCLUSIONS
  The results suggest that FOS and trehalose can effectively enhance the production of the five kinds of bacteriocins evaluated in this study.
  
  
  CONCLUSIONS
  This study offers useful information for not only a new application of FOS and trehalose, but also the potential improvement of food preservation.
authors.affiliation: Institute of Enology and Viticulture, University of Yamanashi, Yamanashi, Japan. yishen@yamanashi.ac.jp
authors.forename: Y-S
authors.initials: YS
authors.lastname: Chen
authors.forename: S
authors.initials: S
authors.lastname: Srionnual
authors.forename: T
authors.initials: T
authors.lastname: Onda
authors.forename: F
authors.initials: F
authors.lastname: Yanagida
mesh_terms: D001430:Bacteriocins / Q000096:biosynthesis* / Q000494:pharmacology; D001709:Biotechnology / Q000379:methods; D005519:Food Preservation / Q000379:methods; D007778:Lactobacillus / Q000187:drug effects / Q000254:growth & development / Q000378:metabolism; D008826:Microbial Sensitivity Tests; D009844:Oligosaccharides / Q000378:metabolism / Q000494:pharmacology*; D013289:Streptococcaceae / Q000187:drug effects / Q000254:growth & development / Q000378:metabolism; D014199:Trehalose / Q000378:metabolism / Q000494:pharmacology*
chemical_list: D001430:Bacteriocins; D009844:Oligosaccharides; D014199:Trehalose