Nematicidal metabolites produced by the endophytic fungus Geotrichum sp. AL4.
From the endophytic fungal strain Geotrichum sp. AL4, cultivated from the leaves of the neem tree (Azadirachta indica), four compounds, 1-4, were isolated from the AcOEt extract, including two new, chlorinated, epimeric 1,3-oxazinane derivatives. All compounds were assessed for their nematicidal activities against the nematodes Bursaphelenchus xylophilus and Panagrellus redivivus, and three out of the four isolates showed noticeable bioactivities.
Li
Guo-Hong
GH
Key Laboratory for Conservation and Utilization of Bio-Resource, Yunnan University, Kunming 650091, PR China.
Yu
Ze-Fen
ZF
Li
Xuan
X
Wang
Xing-Biao
XB
Zheng
Li-Jun
LJ
Zhang
Ke-Qin
KQ
D000818:Animals; D000969:Antinematodal Agents / Q000302:isolation & purification / Q000378:metabolism* / Q000494:pharmacology; D031601:Azadirachta; D005658:Fungi / Q000378:metabolism; D005848:Geotrichum / Q000378:metabolism* / Q000502:physiology; D009348:Nematoda / Q000187:drug effects* / Q000254:growth & development; D010936:Plant Extracts / Q000302:isolation & purification / Q000378:metabolism / Q000494:pharmacology; D018515:Plant Leaves
D000969:Antinematodal Agents; D010936:Plant Extracts