title: Somatostatin-receptor positive brain stem glioma visualized by octreoscan.
abstract: In diffuse brainstem gliomas often surgical biopsies cannot be obtained. The diagnosis relies upon imaging criteria, first line being MRI. Gliomas generally express somatostatin receptors (SSTR), which might enable receptor imaging. We present the case of a female adolescent with acute onset of hallucinations, dysphagia and diplopia. MRI detected a suggestive large pontine glioma. This lesion presented with marked In-111-pentreotide tracer uptake. SSTR-scan provided information about SSTR-expression, tumour viability and extension. Radiopeptide therapy for selected patients might be discussed.
authors.forename: Robert
authors.initials: R
authors.lastname: Pichler
authors.forename: Josef
authors.initials: J
authors.lastname: Pichler
authors.forename: Hamdy
authors.initials: H
authors.lastname: Mustafa
authors.forename: Karin
authors.initials: K
authors.lastname: Nussbaumer
authors.forename: Thomas
authors.initials: T
authors.lastname: Zaunmüller
authors.forename: Raffi
authors.initials: R
authors.lastname: Topakian
mesh_terms: D000328:Adult; D020295:Brain Stem Neoplasms / Q000000981:diagnostic imaging*; D005260:Female; D005910:Glioma / Q000000981:diagnostic imaging*; D006801:Humans; D007205:Indium Radioisotopes; D017481:Receptors, Somatostatin / Q000032:analysis*; D013004:Somatostatin / Q000031:analogs & derivatives*; D015899:Tomography, Emission-Computed, Single-Photon
chemical_list: D007205:Indium Radioisotopes; D017481:Receptors, Somatostatin; D013004:Somatostatin; C081788:pentetreotide