title: [Two pneumococcal vaccines: the 7-valent conjugate vaccine (Prevenar) for children up to the age of 5 years and the 23-valent polysaccharide vaccine (Pneumo 23) for the elderly and specific groups at risk].
abstract: Despite the availability of antibiotics and the care offered by intensive-care units, invasive pneumococcal disease still causes serious illness with high morbidity and mortality. Currently, two vaccines are available in the Netherlands that offer protection against invasive pneumococcal disease: a 7-valent conjugated vaccine and a 23-valent polysaccharide vaccine. Case reports and pharmaceutical use as registered by the Foundation for Pharmaceutical Statistics (SFK) show that general practitioners and pharmacists are not always aware of the appropriate use of both vaccines. For vaccination against pneumococci in children aged 0-5 years, general practitioners should prescribe only the conjugated vaccine. The non-conjugated polysaccharide vaccine is intended especially for the elderly and specific groups at risk. Pharmacists should verify that the pneumococcal vaccines they hand out on prescription are recommended for the age-group of the individuals to whom the vaccine will be administered.
authors.affiliation: Rijksinstituut voor Volksgezondheid en Milieu, Centrum voor Infectieziektebestrijding, Postbak 75, Postbus 1, 3720 BA Bilthoven. sabine.de.greeff@rivm.nl
authors.forename: S C
authors.initials: SC
authors.lastname: de Greeff
authors.forename: E A M
authors.initials: EA
authors.lastname: Sanders
authors.forename: H E
authors.initials: HE
authors.lastname: de Melker
authors.forename: A
authors.initials: A
authors.lastname: van der Ende
authors.forename: P E
authors.initials: PE
authors.lastname: Vermeer
authors.forename: L M
authors.initials: LM
authors.lastname: Schouls
mesh_terms: D000367:Age Factors; D000368:Aged; D002675:Child, Preschool; D005260:Female; D000069443:Heptavalent Pneumococcal Conjugate Vaccine; D006801:Humans; D007223:Infant; D008297:Male; D022401:Meningococcal Vaccines / Q000008:administration & dosage / Q000009:adverse effects; D009426:Netherlands; D011008:Pneumococcal Infections / Q000517:prevention & control*; D022242:Pneumococcal Vaccines / Q000008:administration & dosage* / Q000009:adverse effects; D012307:Risk Factors; D018074:Vaccines, Conjugate / Q000008:administration & dosage / Q000009:adverse effects
chemical_list: C414006:23-valent pneumococcal capsular polysaccharide vaccine; D000069443:Heptavalent Pneumococcal Conjugate Vaccine; D022401:Meningococcal Vaccines; D022242:Pneumococcal Vaccines; D018074:Vaccines, Conjugate