title: [Amyloid cardiomyopathy: a link between cardiology and hematology. A case report of positive response to standard therapy].
abstract: Cardiac involvement in primary systemic amyloidosis, due to amassing of fragments of light chains, is detected in the majority of cases. We report the case of a 56-year-old woman who came to our observation because of symptoms of congestive heart failure. Diagnosis of restrictive cardiomyopathy was made by echocardiographic examination, which showed right ventricular hypertrophy, disarray of interventricular septum and restrictive flow pattern at the mitral valve. Primary systemic amyloidosis was diagnosed by abdominal fat pad biopsy. Laboratory findings confirmed biopsy results, leading to the definite diagnosis of restrictive cardiomyopathy due to IgA kappa monoclonal gammopathy in primary systemic amyloidosis.
authors.affiliation: Departimento di Medicina Clinica, Scienze Cardiovascolari ed Immunologiche, Università degli Studi Federico II, Napoli. gianlucapetrillo@hotmail.com
authors.forename: Gianluca
authors.initials: G
authors.lastname: Petrillo
authors.forename: Lucio
authors.initials: L
authors.lastname: Catalano
authors.forename: Fara
authors.initials: F
authors.lastname: Petruzziello
authors.forename: Sergio
authors.initials: S
authors.lastname: Padula
authors.forename: Claudio
authors.initials: C
authors.lastname: Petrillo
authors.forename: Pio
authors.initials: P
authors.lastname: Caso
mesh_terms: D050153:Abdominal Fat / Q000276:immunology; D000686:Amyloidosis / Q000150:complications* / Q000175:diagnosis* / Q000276:immunology; D001706:Biopsy; D002313:Cardiomyopathy, Restrictive / Q000150:complications* / Q000000981:diagnostic imaging / Q000276:immunology; D004452:Echocardiography; D004562:Electrocardiography; D005260:Female; D006801:Humans; D017380:Hypertrophy, Right Ventricular / Q000209:etiology; D007145:Immunoglobulin kappa-Chains / Q000378:metabolism*; D008875:Middle Aged
chemical_list: D007145:Immunoglobulin kappa-Chains