[Amides from the stems of Uvaria kweichowensis].
Uvaria kweichowensis is a folk nongovernmental herb used to treat cure inflammation and tumour in the Southwest area of China. During the course of our investigation for antitumour agents from the stems of Uvaria kweichowensis, six amides were obtained by means of solvent extraction, chromatography on silica gel and Sephadex LH-20 repeatedly. And their structures were identified as uvariadiamide (1), cepharanone (2), aristololactam A II (3), enterocarpam II (4), aristololactam A Ia (5), and 4,5-dioxodehydroasimilobine (6) on the basis of chemical methods and spectral analyses (EI-MS, 1H NMR, 13C NMR). Among them, compound 1 is a new compound; the other compounds were obtained from this plant for the first time.
Xu
Qiong-ming
QM
College of Pharmacy, Soochow University, Suzhou 215123, China.
Liu
Yan-li
YL
Zhao
Bao-hua
BH
Xu
Li-zhen
LZ
Yang
Shi-lin
SL
Chen
Shao-hua
SH
D000577:Amides / Q000737:chemistry / Q000302:isolation & purification*; D034341:Aristolochic Acids / Q000737:chemistry / Q000302:isolation & purification*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D018547:Plant Stems / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry; D021241:Spectrometry, Mass, Electrospray Ionization; D031046:Uvaria / Q000737:chemistry*
D000577:Amides; D034341:Aristolochic Acids; C541587:aristololactam A II; C541586:cepharanone; C541585:uvariadiamide