title: Predistention of the epidural space before catheter insertion reduces the incidence of intravascular epidural catheter insertion.
abstract: BACKGROUND
  Accidental cannulation of an epidural vein is a common complication associated with epidural anesthesia or analgesia. On the basis of a pilot study and previous reports, we tested the hypothesis that predistention of the epidural space with saline before epidural catheterization would ease catheter insertion and decrease the incidence of this complication.
  
  
  METHODS
  Two-hundred-three laboring women were randomly assigned to receive an epidural with loss of resistance technique with 2 mL (nondistention) or 5 mL saline (distention). In the distention group, the syringe plunger was held closed before epidural catheter insertion. Then in both groups, a test dose of 3 mL of 1.5% lidocaine was injected through the epidural catheter.
  
  
  RESULTS
  There were fewer accidental intravascular catheter placements (2% vs 16%, P = 0.0001) in the distention group, and 91% of patients in this group did not have any unblocked segments versus 67% in the nondistension group (P = 0.0001). The difference in onset time of analgesia was small (5.0 +/- 2 min vs 6 +/- 3 min, P = 0.0001) and not clinically important. The quality of analgesia (visual analog scores and ropivacaine consumption) was similar between groups.
  
  
  CONCLUSIONS
  Distention of the epidural space with 5 mL saline before epidural catheter insertion decreased the incidence of accidental venous cannulation and the number of unblocked segments.
authors.affiliation: Department of Anesthesia, Edith Wolfson Medical Center, Holon and Sackler School of Medicine, Tel Aviv University, Israel.
authors.forename: Shmuel
authors.initials: S
authors.lastname: Evron
authors.forename: Vladimir
authors.initials: V
authors.lastname: Gladkov
authors.forename: Daniel I
authors.initials: DI
authors.lastname: Sessler
authors.forename: Vadim
authors.initials: V
authors.lastname: Khazin
authors.forename: Oscar
authors.initials: O
authors.lastname: Sadan
authors.forename: Mona
authors.initials: M
authors.lastname: Boaz
authors.forename: Tiberiu
authors.initials: T
authors.lastname: Ezri
mesh_terms: D000328:Adult; D015360:Analgesia, Epidural / Q000009:adverse effects* / Q000295:instrumentation / Q000379:methods*; D002404:Catheterization / Q000009:adverse effects / Q000379:methods; D002408:Catheters, Indwelling / Q000009:adverse effects*; D004824:Epidural Space / Q000502:physiology*; D005260:Female; D006801:Humans; D015994:Incidence; D011247:Pregnancy