title: [Morphological diagnosis of plasmocytic myeloma in trephine biopsy (histological and immunohistochemical criteria)].
abstract: Histopathological features of multiple myeloma are reviewed with particular emphasis on its differential diagnosis with reactive plasmocytosis. An algorithm is proposed for examination of bone marrow trephine biopsy in multiple myeloma. Its prognostic factors are discussed. It is concluded that the diagnosis of myeloma in the pathology laboratory should consider cytopathological, histopathological and phenotypic data.
authors.forename: V V
authors.initials: VV
authors.lastname: Baĭkov
mesh_terms: D001706:Biopsy; D001853:Bone Marrow / Q000378:metabolism / Q000473:pathology*; D019002:CD56 Antigen / Q000096:biosynthesis*; D019938:Cyclin D1 / Q000096:biosynthesis*; D006801:Humans; D007150:Immunohistochemistry; D009101:Multiple Myeloma / Q000175:diagnosis* / Q000378:metabolism / Q000473:pathology; D011379:Prognosis
chemical_list: D019002:CD56 Antigen; D019938:Cyclin D1