title: Paroxysmal autonomic instability with dystonia.
abstract: Paroxysmal autonomic instability with dystonia, an under-recognized and poorly understood phenomenon of episodic central dysautonomia is associated with various cerebral insults. Treatment options include benzodiazepines, opioids, and gabapentin. Using an illustrative case, we discuss presentation, pathomechanisms, and management of this condition.
authors.affiliation: National Neuroscience Institute, 11 Jalan Tan Tock Seng, Singapore 308433. sheila_srinivasan@nni.com.sg
authors.forename: Sheila
authors.initials: S
authors.lastname: Srinivasan
authors.forename: C C Tchoyoson
authors.initials: CC
authors.lastname: Lim
authors.forename: Umapathi
authors.initials: U
authors.lastname: Thirugnanam
mesh_terms: D000328:Adult; D000588:Amines / Q000627:therapeutic use; D001342:Autonomic Nervous System Diseases / Q000188:drug therapy / Q000503:physiopathology*; D001569:Benzodiazepines / Q000627:therapeutic use; D001930:Brain Injuries / Q000150:complications; D003509:Cyclohexanecarboxylic Acids / Q000627:therapeutic use; D004421:Dystonia / Q000188:drug therapy / Q000503:physiopathology*; D000077206:Gabapentin; D006801:Humans; D008297:Male; D013577:Syndrome; D005680:gamma-Aminobutyric Acid / Q000627:therapeutic use
chemical_list: D000588:Amines; D003509:Cyclohexanecarboxylic Acids; D001569:Benzodiazepines; D005680:gamma-Aminobutyric Acid; D000077206:Gabapentin