title: Primary diffuse leptomeningeal gliomatosis followed with serial magnetic resonance images.
abstract: We report a case of primary diffuse leptomeningeal gliomatosis (PDLG) followed up with serial magnetic resonance images (MRI). A 45-year-old man manifested with bilateral abducens nerve palsy and meningisms. Repeated MRI revealed diffuse leptomeningeal enhancement throughout the central nervous system without intra-axial mass accompanied with the dilatation of ventricles and focally enlarged cerebral sulci. Brain biopsies showed a leptomeningeal gliomatosis. The MRI findings described here would contribute to the diagnosis of PDLG among other common diseases diffusely spreading along the leptomeningeal structures.
authors.affiliation: Department of Neurological Surgery, Chiba University Graduate School of Medicine 1-8-1, Inohana, Chuo-ku, 260-8670 Chiba, Japan.
authors.forename: Satoshi
authors.initials: S
authors.lastname: Ishige
authors.forename: Yasuo
authors.initials: Y
authors.lastname: Iwadate
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Ishikura
authors.forename: Naokatsu
authors.initials: N
authors.lastname: Saeki
mesh_terms: D017809:Fatal Outcome; D005910:Glioma / Q000378:metabolism / Q000473:pathology*; D006801:Humans; D007089:Image Enhancement; D007150:Immunohistochemistry; D008279:Magnetic Resonance Imaging; D008297:Male; D008577:Meningeal Neoplasms / Q000378:metabolism / Q000473:pathology*; D008875:Middle Aged