Lewis acid-promoted imine synthesis by the insertion of isocyanides into C-H bonds of electron-rich aromatic compounds.
The Lewis acid-promoted insertion of isocyanides into aromatic C-H bonds is reported. An imine functionality containing an array of N-substituents can be introduced directly into electron-rich aromatics in good yields.
Tobisu
Mamoru
M
Department of Applied Chemistry, Faculty of Engineering, Osaka University, Suita, Osaka 565-0871, Japan.
Yamaguchi
Seiji
S
Chatani
Naoto
N