[Effect of antioxidants on the course of experimental pancreatitis].
The chronic experiments on dogs with a pancreatitis model showed that reamberin involved in a complex therapy is conductive to timely positive clinical and laboratory dynamics of disease, particularly to the correction of lipid-induced distress syndrome, and leads to a significant decreasing in the incidence of pancreonecrosis. The positive effect of vitamin E is manifested to a lower degree. The lipid-controlling effect of antioxidants is realized due to a decrease not only in lipid peroxidation rate, but in the phospholipase A2 activity as well.
Vlasov
A P
AP
Trofimov
V A
VA
Misharin
I V
IV
Vlasova
V P
VP
Tsilikina
O V
OV
Keleĭnikov
A B
AB
Atamankin
I V
IV
D000208:Acute Disease; D000818:Animals; D000975:Antioxidants / Q000627:therapeutic use*; D004195:Disease Models, Animal; D004285:Dogs; D004359:Drug Therapy, Combination; D015227:Lipid Peroxidation / Q000187:drug effects; D010195:Pancreatitis / Q000188:drug therapy*; D019283:Pancreatitis, Acute Necrotizing / Q000517:prevention & control*; D010740:Phospholipases / Q000378:metabolism; D013386:Succinates / Q000627:therapeutic use*; D024502:alpha-Tocopherol / Q000627:therapeutic use*
D000975:Antioxidants; D013386:Succinates; D010740:Phospholipases; D024502:alpha-Tocopherol