title: A handheld device for potential point-of-care screening of cancer.
abstract: A simple handheld device based on the fluorescence analysis of 3,6-bis(1-methyl-4-vinylpyridinium)carbazole diiodide (BMVC) stained cells was established for routine screening and potentially for early detection of cancer cells at extremely low cost. Flow cytometry assay further supported the utility of this simple device, where a preliminary study of tissue biopsy showed highly encouraging results.
authors.affiliation: Institute of Atomic and Molecular Sciences, Academia Sinica, P.O. Box 23-166, Taipei, Taiwan 106, Republic of China.
authors.forename: Chi-Chih
authors.initials: CC
authors.lastname: Kang
authors.forename: Cheng-Chung
authors.initials: CC
authors.lastname: Chang
authors.forename: Ta-Chau
authors.initials: TC
authors.lastname: Chang
authors.forename: Li-Jen
authors.initials: LJ
authors.lastname: Liao
authors.forename: Pei-Jen
authors.initials: PJ
authors.lastname: Lou
authors.forename: Wenjun
authors.initials: W
authors.lastname: Xie
authors.forename: Edward S
authors.initials: ES
authors.lastname: Yeung
mesh_terms: D002227:Carbazoles; D002460:Cell Line; D045744:Cell Line, Tumor; D004867:Equipment Design; D005240:Feasibility Studies; D005434:Flow Cytometry; D005456:Fluorescent Dyes; D006801:Humans; D008856:Microscopy, Fluorescence / Q000295:instrumentation / Q000379:methods; D009369:Neoplasms / Q000175:diagnosis*; D019095:Point-of-Care Systems; D011726:Pyridinium Compounds; D012680:Sensitivity and Specificity; D013194:Staining and Labeling
chemical_list: C486012:3,6-bis(1-methyl-4-vinylpyridium)carbazole diiodide; D002227:Carbazoles; D005456:Fluorescent Dyes; D011726:Pyridinium Compounds