title: Investigation of meticillin-resistant Staphylococcus aureus in pigs used for research.
abstract: Meticillin-resistant Staphylococcus aureus (MRSA) was unexpectedly isolated from a pig used for streptozotocin-induced diabetes research. To investigate the possible source of the MRSA isolate, nasal swabs were obtained from the animal herd, and from animal holding rooms, and veterinary and research staff involved in the handling of the animals. Overall, four MRSA isolates were cultured from three pigs and from a clinician/scientist. Two were ST22-MRSA-IV, a human strain type associated with epidemic spread. The other two were ST398-MRSA-V, a strain type associated with pigs. Thus, care should be taken to prevent cross-transmission of MRSA.
authors.affiliation: Department of Experimental Surgery, Singapore General Hospital, Singapore 169608, Singapore.
authors.forename: Darvi Michell Bufete
authors.initials: DMB
authors.lastname: Sergio
authors.affiliation: Department of Pathology, Singapore General Hospital, Singapore 169608, Singapore.
authors.forename: Tse Hsien
authors.initials: TH
authors.lastname: Koh
authors.affiliation: Department of Internal Medicine, Singapore General Hospital, Singapore 169608, Singapore.
authors.forename: Li-Yang
authors.initials: LY
authors.lastname: Hsu
authors.affiliation: Maccine Pte Ltd, Singapore Science Park II, Singapore 117684, Singapore.|Department of Experimental Surgery, Singapore General Hospital, Singapore 169608, Singapore.
authors.forename: Bryan Emmett
authors.initials: BE
authors.lastname: Ogden
authors.affiliation: Department of Experimental Surgery, Singapore General Hospital, Singapore 169608, Singapore.
authors.forename: Angela L H
authors.initials: ALH
authors.lastname: Goh
authors.affiliation: Department of Experimental Surgery, Singapore General Hospital, Singapore 169608, Singapore.
authors.forename: Pierce K H
authors.initials: PKH
authors.lastname: Chow
mesh_terms: D000822:Animal Husbandry; D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D002353:Carrier State / Q000382:microbiology; D003428:Cross Infection / Q000453:epidemiology / Q000382:microbiology / Q000662:veterinary*; D004196:Disease Outbreaks; D018562:Disease Transmission, Infectious / Q000662:veterinary*; D024881:Drug Resistance, Bacterial; D006769:Hospitals, General; D006801:Humans; D017056:Medical Laboratory Personnel; D008712:Methicillin / Q000494:pharmacology; D012307:Risk Factors; D012846:Singapore / Q000453:epidemiology; D013203:Staphylococcal Infections / Q000453:epidemiology / Q000382:microbiology / Q000635:transmission / Q000662:veterinary*; D013211:Staphylococcus aureus / Q000187:drug effects / Q000302:isolation & purification*; D013552:Swine; D013553:Swine Diseases / Q000453:epidemiology* / Q000382:microbiology; D018634:Veterinarians
chemical_list: D000900:Anti-Bacterial Agents; D008712:Methicillin