title: [Investigation of organophosphorous insecticides residue in Chinese crude drugs].
abstract: OBJECTIVE
  To study eleven organophosphorus insecticides residuals in four kinds of Chinese crude drugs.
  
  
  METHODS
  The organophosphorus insecticides were extracted with dichloromethane and cleaned-up with a mixture of Celite 545-activated carbon. The extracts were analyzed by gas chromatography equipped with a flame photometric detector (FPD).
  
  
  RESULTS
  Analysis of fortified Chinese crude drug showed that the average recoveries ranged from 77.5% -112.3% at three different levels, the RSDs were below 10% (n = 4). Trace organophosphorous pesticide residues were found in samples of Rhizoma Atractylodis Macrocephalae and Flos Chrysanthemi.
  
  
  CONCLUSIONS
  A method was established for determination multi-residues in Rhizma Atractylodis Macrocephalae, Radix Curcumae, Bulbus Fritillariae Thunbergii and Flos Chrysanthemi. It provides a method for the risk assessment of organophosphorous pesticide in Chinese crude drugs.
authors.affiliation: Institute of Insecticide and Environmental Toxicology, Huajiachi Campus, Zhejiang University, Hangzhou 310029, China. jlwu@zju.edu.cn
authors.forename: Jia-Lun
authors.initials: JL
authors.lastname: Wu
authors.forename: Xiu-Ping
authors.initials: XP
authors.lastname: Zhan
authors.forename: Yao-Hua
authors.initials: YH
authors.lastname: Zou
authors.forename: Shi-Fei
authors.initials: SF
authors.lastname: Chen
authors.forename: Guang-Zhao
authors.initials: GZ
authors.lastname: Lu
authors.forename: Fu-Gen
authors.initials: FG
authors.lastname: Lai
mesh_terms: D031174:Atractylodes / Q000737:chemistry; D002849:Chromatography, Gas; D031202:Chrysanthemum / Q000737:chemistry; D030024:Curcuma / Q000737:chemistry; D004340:Drug Contamination; D004365:Drugs, Chinese Herbal / Q000737:chemistry*; D031410:Fritillaria / Q000737:chemistry; D009943:Organophosphorus Compounds / Q000032:analysis*; D010573:Pesticide Residues / Q000032:analysis*; D010946:Plants, Medicinal / Q000737:chemistry*
chemical_list: D004365:Drugs, Chinese Herbal; D009943:Organophosphorus Compounds; D010573:Pesticide Residues