Bleeding after circumcision in a newborn receiving sildenafil.
This report describes a case of bleeding as a complication of circumcision in a 2-week-old infant being treated with sildenafil for persistent pulmonary hypertension of the newborn. The vasodilatory effects of sildenafil on the penile vasculature may have contributed to the postoperative bleeding in this patient.
Gamboa
David
D
Children's Hospital & Research Center, Oakland, Calfornia, USA. dgamboa@mail.cho.org
Robbins
Daniel
D
Saba
Ziad
Z
D002944:Circumcision, Male; D006801:Humans; D006976:Hypertension, Pulmonary / Q000188:drug therapy; D007231:Infant, Newborn; D008297:Male; D010879:Piperazines / Q000009:adverse effects* / Q000627:therapeutic use; D019106:Postoperative Hemorrhage / Q000139:chemically induced*; D011687:Purines / Q000009:adverse effects / Q000627:therapeutic use; D000068677:Sildenafil Citrate; D013450:Sulfones / Q000009:adverse effects* / Q000627:therapeutic use; D014665:Vasodilator Agents / Q000009:adverse effects* / Q000627:therapeutic use
D010879:Piperazines; D011687:Purines; D013450:Sulfones; D014665:Vasodilator Agents; D000068677:Sildenafil Citrate