Vitamin D receptor gene polymorphisms and risk of non-Hodgkin's lymphoma.
We studied three vitamin D receptor gene (VDR) polymorphisms (BsmI, TaqI, FokI) in a case-control study of non-Hodgkin's lymphoma. The BsmI B and TaqI t alleles were associated with an increased risk of diffuse large B-cell lymphoma. These findings suggest that variants in VDR may influence lymphomagenesis.
Purdue
Mark P
MP
Lan
Qing
Q
Kricker
Anne
A
Vajdic
Claire M
CM
Rothman
Nathaniel
N
Armstrong
Bruce K
BK
D016022:Case-Control Studies; D015252:Deoxyribonucleases, Type II Site-Specific; D020022:Genetic Predisposition to Disease; D006801:Humans; D008228:Lymphoma, Non-Hodgkin / Q000145:classification / Q000453:epidemiology / Q000235:genetics*; D009517:New South Wales / Q000453:epidemiology; D012150:Polymorphism, Restriction Fragment Length; D020641:Polymorphism, Single Nucleotide; D018167:Receptors, Calcitriol / Q000235:genetics*; D012306:Risk
D018167:Receptors, Calcitriol; C053864:endodeoxyribonuclease BsmI; C035042:endodeoxyribonuclease FokI; D015252:Deoxyribonucleases, Type II Site-Specific; C027046:TCGA-specific type II deoxyribonucleases