title: Efficacy of Slim339 in reducing body weight of overweight and obese human subjects.
abstract: A double-blind, randomized, parallel-group, placebo-controlled study has been carried out in order to evaluate the effect of orally self-administered Slim339, a proprietary fixed combination of Garcinia cambogia extract with calcium pantothenate (standardized for the content of hydroxycitric acid and pantothenic acid) and extracts of Matricaria chamomilla, Rosa damascena, Lavandula officinalis and Cananga odorata, on body weight in overweight and obese volunteers. During a 60-day treatment period, the average reduction in body weight for the group receiving Slim339 (n = 30) was 4.67% compared with 0.63% for the placebo group (n = 28) (p < 0.0001). Weight losses of >or=3 kg were recorded for 23 subjects in the treatment group and only one in the placebo group. It is concluded that Slim339 represents a potential therapy for obesity.
authors.affiliation: Republican Endocrinology Center, Ministry of Health of Armenia, Yerevan, Armenia.
authors.forename: Edward
authors.initials: E
authors.lastname: Toromanyan
authors.forename: Gayane
authors.initials: G
authors.lastname: Aslanyan
authors.forename: Elmira
authors.initials: E
authors.lastname: Amroyan
authors.forename: Emil
authors.initials: E
authors.lastname: Gabrielyan
authors.forename: Alexander
authors.initials: A
authors.lastname: Panossian
mesh_terms: D000328:Adult; D019440:Anti-Obesity Agents / Q000627:therapeutic use*; D001835:Body Weight / Q000187:drug effects*; D004311:Double-Blind Method; D005260:Female; D029761:Garcinia cambogia; D006801:Humans; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000188:drug therapy*; D010205:Pantothenic Acid / Q000494:pharmacology / Q000627:therapeutic use*; D008517:Phytotherapy; D010936:Plant Extracts / Q000494:pharmacology / Q000627:therapeutic use*
chemical_list: D019440:Anti-Obesity Agents; D010936:Plant Extracts; C527594:Slim339; D010205:Pantothenic Acid