Angular-interstitial pregnancy treated with minimally invasive surgery after adjuvant methotrexate medical therapy.
BACKGROUND
Angular-interstitial pregnancy is a rare and potentially dangerous occurrence of ectopic pregnancy for which appropriate treatment has not been established.


METHODS
A 41-year-old woman with a history of ectopic pregnancy was treated with a combined regimen of conservative treatment comprising medical therapy with methotrexate and a minimally invasive laparoscopic-assisted surgical approach. Results The patient had an unremarkable postoperative course and was discharged after 32 hours. A transvaginal ultrasound scan control 2 weeks later revealed a normal uterine wall, with normal uterine adnexa.


CONCLUSIONS
With our combined treatment approach we avoided hysterectomy, and we achieved a more adequate uterine repair, improving future fertility.
Ciavattini
Andrea
A
Institute of Obstetrics and Gynecology, Università Politecnica delle Marche, Ancona, Italy. andreac@univpm.it
Cerè
Isabella
I
Tsiroglou
Dimitrios
D
Caselli
Francesco Maria
FM
Tranquilli
Andrea Luigi
AL
D000020:Abortifacient Agents, Nonsteroidal / Q000008:administration & dosage / Q000009:adverse effects*; D000328:Adult; D005260:Female; D006801:Humans; D015907:Hysteroscopy; D010535:Laparoscopy; D008727:Methotrexate / Q000008:administration & dosage*; D011247:Pregnancy; D011271:Pregnancy, Ectopic / Q000000981:diagnostic imaging / Q000628:therapy*; D014463:Ultrasonography
D000020:Abortifacient Agents, Nonsteroidal; D008727:Methotrexate