title: [Distribution of hepatitis B virus genotype B subgenotype in China].
abstract: OBJECTIVE
  To investigate the distribution of hepatitis B virus (HBV) genotype B subgenotype in China.
  
  
  METHODS
  A cohort of 511 patients with chronic HBV genotype B infection, collected from 7 centers across China, were analyzed by using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) or nucleotide sequencing.
  
  
  RESULTS
  For the 511 patients, only subgenotype Ba was identified and subgenotype Bj was not found.
  
  
  CONCLUSIONS
  In China, subgenotype Ba was the most prevalent HBV strains, while subgenotype Bj was very rarely found.
authors.affiliation: Department of Infectious Diseases, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
authors.forename: Yue-hua
authors.initials: YH
authors.lastname: Huang
authors.forename: Bin
authors.initials: B
authors.lastname: Zhou
authors.forename: Zhan-hui
authors.initials: ZH
authors.lastname: Wang
authors.forename: Shi-wu
authors.initials: SW
authors.lastname: Ma
authors.forename: Min-feng
authors.initials: MF
authors.lastname: Liang
authors.forename: Jin-lin
authors.initials: JL
authors.lastname: Hou
mesh_terms: D002681:China; D004279:DNA, Viral / Q000235:genetics; D005838:Genotype; D006509:Hepatitis B / Q000821:virology*; D006515:Hepatitis B virus / Q000145:classification / Q000235:genetics* / Q000302:isolation & purification; D006801:Humans; D010802:Phylogeny; D012150:Polymorphism, Restriction Fragment Length
chemical_list: D004279:DNA, Viral