Paroxysmal autonomic instability with dystonia.
Paroxysmal autonomic instability with dystonia, an under-recognized and poorly understood phenomenon of episodic central dysautonomia is associated with various cerebral insults. Treatment options include benzodiazepines, opioids, and gabapentin. Using an illustrative case, we discuss presentation, pathomechanisms, and management of this condition.
Srinivasan
Sheila
S
National Neuroscience Institute, 11 Jalan Tan Tock Seng, Singapore 308433. sheila_srinivasan@nni.com.sg
Lim
C C Tchoyoson
CC
Thirugnanam
Umapathi
U
D000328:Adult; D000588:Amines / Q000627:therapeutic use; D001342:Autonomic Nervous System Diseases / Q000188:drug therapy / Q000503:physiopathology*; D001569:Benzodiazepines / Q000627:therapeutic use; D001930:Brain Injuries / Q000150:complications; D003509:Cyclohexanecarboxylic Acids / Q000627:therapeutic use; D004421:Dystonia / Q000188:drug therapy / Q000503:physiopathology*; D000077206:Gabapentin; D006801:Humans; D008297:Male; D013577:Syndrome; D005680:gamma-Aminobutyric Acid / Q000627:therapeutic use
D000588:Amines; D003509:Cyclohexanecarboxylic Acids; D001569:Benzodiazepines; D005680:gamma-Aminobutyric Acid; D000077206:Gabapentin