title: What factors influence the results of coronary artery bypass grafting in aged patients?
abstract: OBJECTIVE
  Early and late results were studied in order to improve the indication for coronary artery bypass grafting (CABG) and to enhance
  
  
  RESULTS
  
  
  
  METHODS
  A total of 1 973 patients aged 70 years and older who had undergone isolated CABG were studied. Elective operations (EL) were performed in 1 716 patients and 257 patients underwent urgent or emergency operations (UR/EM). Patients were divided into two groups; 104 patients aged 80 years and older (Oct. Group) and 1 869 patients of septuagenarians (Sept. Group). There were no differences between the groups in the number of diseased vessels.
  
  
  RESULTS
  Total operative mortality rates in the Oct. and the Sept. groups were 7% and 4%, respectively. The operative mortality of elective surgery was 4% in both groups. The operative mortality of UR/EM CABG was significantly higher in the Oct. group than in the Sept. group (21% vs 6%). Operative mortality was significantly higher in patients with preoperative poor (<49%) left ventricular ejection fraction (LVEF) than in patients with higher (>50%) LVEF (6% vs 3%). Among preoperative risk factors, diabetes mellitus and peripheral vascular disease were significant contributory factors to operative death. In the follow-up study, 70% patients of the Oct. group and 72% patients of the Sept. group survived. Preoperative number of diseased vessels and number of CABG grafts did not influence the early and late
  
  
  RESULTS
  
  
  
  CONCLUSIONS
  Preoperative poor LVEF, diabetes mellitus and peripheral vascular disease were significant contributory factors to operative death. When feasible, CABG in octogenarians should be performed electively.
authors.affiliation: Department of Cardiac Surgery, Austin Hospital University of Melbourne, Melbourne, Australia. ishikawa@med.teikyo-u.ac.jp
authors.forename: S
authors.initials: S
authors.lastname: Ishikawa
authors.forename: B F
authors.initials: BF
authors.lastname: Buxton
authors.forename: N
authors.initials: N
authors.lastname: Manson
authors.forename: A
authors.initials: A
authors.lastname: Hadj
authors.forename: S
authors.initials: S
authors.lastname: Seevanayagam
authors.forename: J S
authors.initials: JS
authors.lastname: Raman
authors.forename: G
authors.initials: G
authors.lastname: Matalanis
authors.forename: A
authors.initials: A
authors.lastname: Rosalion
authors.forename: K
authors.initials: K
authors.lastname: Ueda
mesh_terms: D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D001026:Coronary Artery Bypass / Q000009:adverse effects* / Q000401:mortality*; D003324:Coronary Artery Disease / Q000150:complications / Q000401:mortality* / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D018579:Patient Selection; D012086:Reoperation; D012189:Retrospective Studies; D012307:Risk Factors; D012720:Severity of Illness Index; D013318:Stroke Volume; D016896:Treatment Outcome