title: [Research progress on therapeutic mechanism of depression treated by traditional chinese medicine].
abstract: To review the reports concering the mechanisms of traditional Chinese medicine in treating depression in recent years and combine research achievements of the authors, we summarized the research progress on therapeutic mechanism of depression treated by traditional Chinese medicine. Previous researches proved that traditional Chinese medicine played antidepressant role by affecting the monoamine neurotransmitters, excitotoxicity, Hypothalamus-Pituitary-Adrenal axis, hippocampal neurons and neurotrophic factor et al. It has suggested that depression treated by traditional Chinese medicine is through a lot of channels, target spots and levels.
authors.affiliation: Department of pharmacy, Zhejiang University of Traditional Chinese Medicine, Hangzhou 31005, China.
authors.forename: Qing-Qiu
authors.initials: QQ
authors.lastname: Mao
authors.forename: Zhen
authors.initials: Z
authors.lastname: Huang
mesh_terms: D000818:Animals; D000928:Antidepressive Agents / Q000627:therapeutic use*; D015306:Biogenic Monoamines / Q000378:metabolism; D003866:Depressive Disorder / Q000188:drug therapy* / Q000378:metabolism / Q000473:pathology; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D018698:Glutamic Acid / Q000378:metabolism; D006801:Humans; D009414:Nerve Growth Factors / Q000378:metabolism; D008517:Phytotherapy
chemical_list: D000928:Antidepressive Agents; D015306:Biogenic Monoamines; D004365:Drugs, Chinese Herbal; D009414:Nerve Growth Factors; D018698:Glutamic Acid