[Postoperative diabetes insipidus after transsphenoidal resection of pituitary tumor].
OBJECTIVE
To study the prevention and treatment of postoperative diabetes insipidus after removal of pituitary tumor through transsphenoidal operation, to decrease the incidence of postoperative complications and improve the treatment of pituitary tumor.


METHODS
The clinical data of 86 cases of transsphenoidal resection of pituitary tumor in recent 8 years were retrospectively reviewed, including 35 endoscopic operation and 51 microscopic operation. The incidence, prevention and treatment of diabetes insipidus were statistically analysed.


RESULTS
There were 18 cases of postoperative diabetes insipidus in total of 86 operations, including 15 acute cases, 3 delayed cases. Twelve were temporary , which recovered within 1 week. After prompt treatment, 14 recovered within 1 week, 4 recovered within 2 weeks. No persistent diabetes insipidus was found.


CONCLUSIONS
The key points to prevent postoperative diabetes insipidus lay in the improvement of operative skills, careful protection during operation and avoidance of unnecessary injury. In case of diabetes insipidus occurred, rational use of antidiuretics and correction of electrolyte balance were effective in the treatment of postoperative diabetes insipidus.
Tao
Jia
J
Otorhinolaryngology Hospita, First Affiliated Hospital of Sun Yat-sen University, Otorhinolaryngology Institute of Sun Yat-sen University, Guangzhou 510080, China.
Wen
Wei-Ping
WP
Lei
Wen-Bin
WB
Chen
Zhong-Ping
ZP
Su
Zhen-Zhong
ZZ
Mu
Yong-Gao
YG
Xu
Geng
G
D000328:Adult; D003919:Diabetes Insipidus / Q000209:etiology*; D004724:Endoscopy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010911:Pituitary Neoplasms / Q000601:surgery; D011183:Postoperative Complications / Q000209:etiology*; D012189:Retrospective Studies; D013101:Sphenoid Sinus / Q000601:surgery