title: Role of prophylactic endoscopic sphincterotomy in patients with acute biliary pancreatitis due to transient common bile duct obstruction.
abstract: OBJECTIVE
  The role of prophylactic endoscopic sphincterotomy in patients with transient common bile duct obstruction is controversial. The aim of this study was to assess the value of performing prophylactic endoscopic sphincterotomy in patients suffering from acute biliary pancreatitis and absent common bile duct stones on endoscopic retrograde cholangiopancreatography (ERCP).
  
  
  METHODS
  Hospital notes of patients admitted to our unit with a diagnosis of acute pancreatitis from January 2000 to January 2005 were reviewed. Endoscopic sphincterotomy was performed when patients were deemed unfit for cholecystectomy, suffering from a severe attack of acute pancreatitis and/or showing evidence of transient common bile duct obstruction. The outcomes of patients with and without endoscopic sphincterotomy were compared.
  
  
  RESULTS
  A total of 427 patients were admitted with a diagnosis of acute pancreatitis during the study period. Eighty-eight patients with absent common bile duct stones on ERCP were identified. Endoscopic sphincterotomy was performed in 71 patients and not performed in 17 patients. There was no significant difference in recurrent pancreatitis rates (1.4% vs 5.8%, P = 0.35), recurrent biliary complication rates (5.6% vs 5.9%, P = 1) or mortality rates (5.8% vs 1.5%, P = 0.35). The time to recurrent complications (38.4 days vs 41.0 days, P = 0.38) was not significantly different between the two groups. There was no ERCP-related morbidity or mortality.
  
  
  CONCLUSIONS
  Prophylactic endoscopic sphincterotomy is not recommended in patients with transient common bile duct obstruction or as an option to cholecystectomy in elderly patients. Early cholecystectomy should be performed.
authors.affiliation: Department of Surgery, North District Hospital, Sheung Shui, Hong Kong SAR, China. anthonyteoh@surgery.cuhk.edu.hk
authors.forename: Anthony Y B
authors.initials: AY
authors.lastname: Teoh
authors.forename: Michael C M
authors.initials: MC
authors.lastname: Poon
authors.forename: Heng Tat
authors.initials: HT
authors.lastname: Leong
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D014670:Ampulla of Vater / Q000601:surgery; D002760:Cholangiopancreatography, Endoscopic Retrograde; D002779:Cholestasis / Q000209:etiology* / Q000601:surgery*; D003135:Common Bile Duct; D003137:Common Bile Duct Diseases / Q000601:surgery*; D004724:Endoscopy; D005260:Female; D005705:Gallbladder Diseases / Q000175:diagnosis*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010195:Pancreatitis / Q000175:diagnosis*; D012189:Retrospective Studies; D009803:Sphincter of Oddi / Q000601:surgery; D016717:Sphincterotomy, Endoscopic / Q000379:methods*; D016896:Treatment Outcome