title: The OECD Blue Book on Recombinant DNA Safety Considerations: it's influence on ISBR and EFSA activities.
abstract: Biosafety regulatory frameworks are intended to serve as mechanisms for ensuring the safe use of biotechnology products without imposing unacceptable risk to human health or the environment, or unintended constraints to technology transfer. The OECD Blue Book on "Recombinant DNA Safety Considerations", setting out principles and concepts for handling genetically modified organisms safely outside of contained laboratory conditions, was a milestone in the history of biotechnology. The "Recombinant DNA Safety Considerations" definitively became the major resource for the formulation of national regulatory frameworks and international regulations, including the Cartagena Protocol.
authors.affiliation: Federal Biological Research Centre for Agriculture and Forestry, Institute for Plant Virology, Microbiology and Biosafety, Braunschweig, Germany. J.Schiemann@BBA.DE
authors.forename: Joachim
authors.initials: J
authors.lastname: Schiemann
mesh_terms: D004274:DNA, Recombinant / Q000235:genetics*; D004777:Environment; D005060:Europe; D017408:Guidelines as Topic; D007390:International Agencies; D030781:Organisms, Genetically Modified; D012013:Reference Books; D018570:Risk Assessment / Q000592:standards
chemical_list: D004274:DNA, Recombinant