In vivo reflectance confocal microscopy imaging of melanocytic skin lesions: consensus terminology glossary and illustrative images.
BACKGROUND
Reflectance confocal microscopy (RCM) has been used for over 10 years for in vivo skin imaging. However, to date no standard RCM terminology has been published.


OBJECTIVE
To establish a glossary of terms for RCM evaluation of melanocytic lesions.


METHODS
Prominent RCM researchers were presented with RCM images of melanocytic lesions. Reviewers evaluated RCM images for image quality, lesion architecture, and cellular details. Reviewers could utilize published descriptors or contribute unpublished terminology to describe lesion attributes. An online meeting was conducted to reach consensus that integrates and defines existing and new RCM descriptive terms.


RESULTS
We present a glossary with descriptors of image quality, normal skin morphology, lesion architecture, and cellular details for RCM evaluation of melanocytic lesions.


CONCLUSIONS
Usefulness of the glossary in RCM diagnosis of melanocytic lesions needs to be assessed.


CONCLUSIONS
Standardization of terminology is important toward implementation of RCM in the clinical setting.
Scope
Alon
A
Dermatology Service, Memorial Sloan-Kettering Cancer Center, New York, New York 10022, USA.
Benvenuto-Andrade
Cristiane
C
Agero
Anna-Liza C
AL
Malvehy
Josep
J
Puig
Susana
S
Rajadhyaksha
Milind
M
Busam
Klaus J
KJ
Marra
Diego E
DE
Torres
Abel
A
Propperova
Iva
I
Langley
Richard G
RG
Marghoob
Ashfaq A
AA
Pellacani
Giovanni
G
Seidenari
Stefania
S
Halpern
Allan C
AC
Gonzalez
Salvador
S
D006801:Humans; D008544:Melanocytes / Q000473:pathology*; D018613:Microscopy, Confocal; D009508:Nevus, Pigmented / Q000473:pathology*; D012867:Skin / Q000473:pathology*; D012871:Skin Diseases / Q000473:pathology; D009626:Terminology as Topic