title: Cerebellar astrocytoma presenting with precocious puberty in a girl. Case report.
abstract: Central precocious puberty in girls is uncommon and tends to be idiopathic in most cases. In about 20 to 30% of cases there is an intracranial mass lesion. The common lesions are hypothalamic hamartomas, optic nerve gliomas, suprasellar arachnoid cysts, hydrocephalus, germinomas, and other sellar/suprasellar lesions. Central precocious puberty secondary to a cerebellar astrocytoma is extremely rare. The authors report the first case in a girl who presented with several episodes of bleeding per vaginum. There was no clinical or radiological evidence of raised intracranial pressure.
authors.affiliation: Departments of Neurosurgery, Royal Children's Hospital, Melbourne, Australia. Josanv@aol.com
authors.forename: Vivek Anand
authors.initials: VA
authors.lastname: Josan
authors.forename: Craig Douglas
authors.initials: CD
authors.lastname: Timms
authors.forename: Christian
authors.initials: C
authors.lastname: Rickert
authors.forename: David
authors.initials: D
authors.lastname: Wallace
mesh_terms: D001254:Astrocytoma / Q000150:complications / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D002528:Cerebellar Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D002531:Cerebellum / Q000473:pathology / Q000601:surgery; D002675:Child, Preschool; D003937:Diagnosis, Differential; D004292:Dominance, Cerebral; D004958:Estradiol / Q000097:blood; D005260:Female; D012739:Gonadal Steroid Hormones / Q000097:blood; D006801:Humans; D008279:Magnetic Resonance Imaging; D008598:Menstruation / Q000502:physiology; D011629:Puberty, Precocious / Q000209:etiology*
chemical_list: D012739:Gonadal Steroid Hormones; D004958:Estradiol