title: Visual function in infants with non-syndromic craniosynostosis.
abstract: The aim of this study was to assess various aspects of visual function in children with single-suture, non-syndromic craniosynostosis. Thirty-eight infants (28 males, 10 females; age range 3.5-13mo, mean age 7mo, 11 with plagiocephaly, 12 with trigonocephaly, and 15 with scaphocephaly), were assessed with a battery of tests specifically designed to assess various aspects of visual function in infancy. Thirty-two of the 38 infants had at least one abnormality on one of the aspects of visual function assessed. Abnormal eye movements were found in eight infants of the whole cohort and were mainly found in infants with plagiocephaly (6/11), who also had frequent visual field abnormalities (5/11). In contrast, fixation shift, an aspect of visual function related to the integrity of parietal lobes, was more frequently abnormal in patients with scaphocephaly. Our results suggest that the presence and severity of visual impairment is related to the type of craniosynostosis. Follow-up studies after surgical correction are needed to evaluate the possible beneficial effects of reconstructive surgery on visual function.
authors.affiliation: Pediatric Neurology Unit, Catholic University, Rome, Italy.
authors.forename: D
authors.initials: D
authors.lastname: Ricci
authors.forename: G
authors.initials: G
authors.lastname: Vasco
authors.forename: G
authors.initials: G
authors.lastname: Baranello
authors.forename: A
authors.initials: A
authors.lastname: Salerni
authors.forename: R
authors.initials: R
authors.lastname: Amante
authors.forename: G
authors.initials: G
authors.lastname: Tamburrini
authors.forename: A
authors.initials: A
authors.lastname: Dickmann
authors.forename: C
authors.initials: C
authors.lastname: Di Rocco
authors.forename: F
authors.initials: F
authors.lastname: Velardi
authors.forename: E
authors.initials: E
authors.lastname: Mercuri
mesh_terms: D001288:Attention / Q000502:physiology; D003398:Craniosynostoses / Q000503:physiopathology*; D003941:Diagnostic Techniques, Ophthalmological; D005133:Eye Movements / Q000502:physiology; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D014787:Vision Tests; D015348:Vision, Binocular; D014785:Vision, Ocular / Q000502:physiology*; D014792:Visual Acuity / Q000502:physiology; D014794:Visual Fields / Q000502:physiology