title: Adenoid cystic carcinoma of the lung: interest of 18FDG PET/CT in the management of an atypical presentation.
abstract: Adenoid cystic carcinoma (ACC) is a common head and neck tumor originating from salivary glands but that can also exceptionally develop in the trachea and major bronchi. ACC is generally considered as a slow-growing, low-grade malignancy with prolonged clinical course. Metastases are very unusual and recurrences are more often local. Treatment for localized ACC is surgery. We here report for the first time a case of lung ACC with a synchronous liver metastasis proved by biopsy. Moreover, we report the interest of performing a 18FDG PET-CT as both primary tumor and liver metastasis presented an intense FDG uptake. The specificity of the liver 18FDG uptake was confirmed by Glut-1 positive immunostaining. We propose that 18FDG PET-CT should be considered in the initial staging of lung ACC in selected patients.
authors.affiliation: Service de Pneumologie-Allergologie, Clinique des Voies Respiratoires, Hôpital Larrey, Chemin de Pouvourville, 31059 Toulouse Cedex, France.
authors.forename: Marion
authors.initials: M
authors.lastname: Campistron
authors.forename: Isabelle
authors.initials: I
authors.lastname: Rouquette
authors.forename: Fréderick
authors.initials: F
authors.lastname: Courbon
authors.forename: Valérie
authors.initials: V
authors.lastname: Chabbert
authors.forename: Philippe
authors.initials: P
authors.lastname: Rochaix
authors.forename: Grégoire
authors.initials: G
authors.lastname: Prévot
authors.forename: Sophie
authors.initials: S
authors.lastname: Laroumagne
authors.forename: Laurent
authors.initials: L
authors.lastname: Têtu
authors.forename: Alain
authors.initials: A
authors.lastname: Didier
authors.forename: Julien
authors.initials: J
authors.lastname: Mazières
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D003528:Carcinoma, Adenoid Cystic / Q000000981:diagnostic imaging* / Q000473:pathology; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008175:Lung Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D049268:Positron-Emission Tomography; D014057:Tomography, X-Ray Computed
chemical_list: D019788:Fluorodeoxyglucose F18