title: Non-typhoidal Salmonella bacteremia in adults.
abstract: OBJECTIVE
  Very few studies have examined prognostic factors in adult patients with non-typhoidal Salmonella (NTS) bacteremia. The purpose of this study was to identify the prognostic factors of these patients.
  
  
  METHODS
  A total of 79 episodes of NTS bacteremia were identified in 73 patients between January 2001 and December 2003. Susceptibilities to various antimicrobials were determined using disk-diffusion tests and National Committee for Clinical Laboratory Standards criteria. Multiple logistic regression was used to evaluate the relationship between patients' characteristics and covariates of mortality.
  
  
  RESULTS
  There were only 5 episodes (6%) of gastroenteritis, two of which were due to Salmonella septicemia contracted abroad. Potentially predisposing factors were identifiable in 51 episodes (65%). Infections in 24 patients (30%) were due to serogroup B Salmonella and in 22 patients (28%), to serogroup C Salmonella. A logistic regression analysis selected two variables as independently influencing prognosis: coma (p=0.006) and septic shock (p=0.002).
  
  
  CONCLUSIONS
  Thus, most adult patients with NTS bacteremia do not develop gastroenteritis. Patients in shock or coma have poor prognosis, and susceptibility to third-generation cephalosporins, cefepime, and carbapenem is high.
authors.affiliation: Section of Infectious Diseases, Department of Medicine, Taipei Veterans General Hospital, and National Yang-Ming University, Taipei, Taiwan.
authors.forename: Yung Feng
authors.initials: YF
authors.lastname: Yen
authors.forename: Yi Chun
authors.initials: YC
authors.lastname: Lin
authors.forename: Te Li
authors.initials: TL
authors.lastname: Chen
authors.forename: Yin Yin
authors.initials: YY
authors.lastname: Chen
authors.forename: Mei Lin
authors.initials: ML
authors.lastname: Lin
authors.forename: Fu Der
authors.initials: FD
authors.lastname: Wang
authors.forename: Chen Yi
authors.initials: CY
authors.lastname: Liu
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000378:metabolism / Q000627:therapeutic use*; D016470:Bacteremia / Q000382:microbiology / Q000503:physiopathology*; D003128:Coma; D024881:Drug Resistance, Bacterial; D005260:Female; D005759:Gastroenteritis / Q000382:microbiology; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D012475:Salmonella / Q000145:classification / Q000187:drug effects / Q000302:isolation & purification*; D012480:Salmonella Infections / Q000188:drug therapy / Q000382:microbiology / Q000503:physiopathology*; D012772:Shock, Septic / Q000382:microbiology / Q000503:physiopathology
chemical_list: D000900:Anti-Bacterial Agents