[Estrogens, trypsyne-like proteinases and carboxipeptidases A and B at womb body tumors].
The correlation between activity of trypsyn-like proteases, carboxypeptidases A and B and estrogen level in the womb body has been studied. Correlation analysis suggest the existence of induction of trypsyn-like proteases by estrogens, these proteases activate carboxypeptidases A and B. It has been shown, that carboxypeptidases can play sufficient role in the malignisation process.
Vovchuk
I L
IL
Chernadchuk
S S
SS
Petrov
S A
SA
D043424:Carboxypeptidase B / Q000096:biosynthesis*; D043422:Carboxypeptidases A / Q000096:biosynthesis*; D016889:Endometrial Neoplasms / Q000201:enzymology*; D004790:Enzyme Induction; D004967:Estrogens / Q000378:metabolism*; D005260:Female; D015972:Gene Expression Regulation, Neoplastic; D006801:Humans; D012697:Serine Endopeptidases / Q000096:biosynthesis*
D004967:Estrogens; C114880:trypsin-like serine protease; D043422:Carboxypeptidases A; D043424:Carboxypeptidase B; D012697:Serine Endopeptidases