title: [Identification of binding proteins to the PDZ domain of ERBIN].
abstract: OBJECTIVE
  To identify the binding proteins to PDZ domain of ERBIN.
  
  
  METHODS
  Using PDZ domain of ERBIN as the bait, yeast two-hybrid technology was employed to screen the human lymphocyte leukemia cells MATCHMAKER cDNA library. The protein interaction was identified by immunoprecipitation.
  
  
  RESULTS
  A PDZ-binding protein, TAX1, was identified.
  
  
  CONCLUSIONS
  TAX1 is a novel binding protein to PDZ domain of ERBIN.
authors.affiliation: National Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, CAMS and PUMC, Beijing 100005, China.
authors.forename: Chun-jiao
authors.initials: CJ
authors.lastname: Song
authors.forename: De-xian
authors.initials: DX
authors.lastname: Zheng
authors.forename: Yan-xin
authors.initials: YX
authors.lastname: Liu
mesh_terms: D048868:Adaptor Proteins, Signal Transducing / Q000378:metabolism*; D045744:Cell Line, Tumor; D006801:Humans; D047468:Immunoprecipitation; D047908:Intracellular Signaling Peptides and Proteins / Q000378:metabolism*; D009363:Neoplasm Proteins / Q000378:metabolism*; D054731:PDZ Domains; D011485:Protein Binding; D020798:Two-Hybrid System Techniques
chemical_list: D048868:Adaptor Proteins, Signal Transducing; C413364:ERBIN protein, human; D047908:Intracellular Signaling Peptides and Proteins; D009363:Neoplasm Proteins; C120635:TAX1BP1 protein, human