Plasma cytokine levels in ulcerative colitis.
OBJECTIVE
Some immunological factors are responsible in the pathogenesis of ulcerative colitis. There is a relationship between cytokines and ulcerative colitis.


METHODS
In this study 20 ulcerative colitis patients (mean age 36.2 years old, 9 women, 11 men) and 20 healthy control groups (mean age 27.2 years old, 11 women, 9 men) were involved in the study.


RESULTS
We established that IL-2Rsp, IL-6, IL-8 and IL-10 levels were different at the patients and control groups (p < 0.005). TNF-alpha and IL-1 beta were similar at the both groups.


CONCLUSIONS
According to these results, IL-2Rsp, IL-6, 11-8 and IL-10 play an important role in the pathogenesis of ulcerative colitis. We consider that these cytokines are beneficial parameters in the diagnosis, treatment and prognosis of ulcerative colitis.
Goral
Vedat
V
Department of Gastroenterology, Dicle University School of Medicine, Diyarbakir, Turkey. vegoral@hotmail.com
Celenk
Tahir
T
Kaplan
Abdurahman
A
Sit
Dede
D
D000328:Adult; D014408:Biomarkers, Tumor / Q000097:blood*; D003093:Colitis, Ulcerative / Q000175:diagnosis*; D016207:Cytokines / Q000097:blood*; D005260:Female; D006801:Humans; D008297:Male; D011379:Prognosis
D014408:Biomarkers, Tumor; D016207:Cytokines