title: Does concordance with guideline triage recommendations affect clinical care of patients with possible acute coronary syndrome?
abstract: BACKGROUND
  The Agency for Health Care Policy and Research (AHCPR) Unstable Angina Practice Guideline recommends outpatient management for patients at low risk and admission to a monitored bed for patients at intermediate-high risk of adverse short-term outcomes, but the clinical consequences of adhering to these recommendations are unclear.
  
  
  METHODS
  This analysis included 7466 adults who presented to the emergency department (ED) with symptoms of possible acute coronary syndrome (ACS) and who participated in 3 prospective clinical effectiveness trials during the period 1993 to 2001. The authors used logistic regression to assess the impact of concordance with guideline triage recommendations on subsequent diagnostic testing, follow-up care, and 30-day mortality and applied propensity score methods to adjust for selection bias.
  
  
  RESULTS
  Among low-risk patients (n = 1099), ED discharge was not associated with higher mortality and did not increase the need for emergency care or hospitalization during follow-up (adjusted odds ratio [OR] = 1.0, 95% confidence interval [CI] = 0.63-1.6 for ED revisits); however, 1.7% of discharged low-risk patients had confirmed ACS. Among intermediate- to high-risk patients (n = 6367), admission to a monitored bed was not associated with reduction in 30-day mortality but significantly reduced the need for follow-up ED care (adjusted OR = 0.81, 95% CI = 0.69-0.96).
  
  
  CONCLUSIONS
  This analysis supports the practice of discharging low-risk ED patients with symptoms of possible ACS but highlights the need to arrange timely follow-up (or to perform additional risk stratification in the ED prior to discharge). It also confirms the benefit of admitting ED patients with intermediate- to high-risk characteristics to a monitored bed.
authors.affiliation: Department of Medicine, University of Iowa Carver College of Medicine, Iowa City, USA. david-katz@uiowa.edu
authors.forename: David A
authors.initials: DA
authors.lastname: Katz
authors.forename: Jeffrey
authors.initials: J
authors.lastname: Dawson
authors.forename: Joni R
authors.initials: JR
authors.lastname: Beshansky
authors.forename: Peter S
authors.initials: PS
authors.lastname: Rahko
authors.forename: Tom P
authors.initials: TP
authors.lastname: Aufderheide
authors.forename: Mark
authors.initials: M
authors.lastname: Bogner
authors.forename: Hocine
authors.initials: H
authors.lastname: Tighouart
authors.forename: Harry P
authors.initials: HP
authors.lastname: Selker
mesh_terms: D000208:Acute Disease; D000328:Adult; D000789:Angina, Unstable / Q000401:mortality / Q000628:therapy; D003327:Coronary Disease / Q000401:mortality / Q000628:therapy*; D004636:Emergency Service, Hospital / Q000458:organization & administration* / Q000592:standards; D005260:Female; D019983:Guideline Adherence; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D010351:Patient Discharge; D017410:Practice Guidelines as Topic / Q000592:standards*; D018570:Risk Assessment; D013577:Syndrome; D016896:Treatment Outcome; D014218:Triage / Q000592:standards*