[Typological characteristics of behavior in strains of rats bred for enhancement and absence of pendulum movements. Association with brain monoamines].
Typological characteristics of behavior were studied in rats bred for enhancement (PM+) and absence (PM-) of pendulum movements. Excitement in different test situations was manifest in PM+ rats, whereas passive defensive reactions were characteristic of PM- rats. Increased excitability of PM+ rats was expressed in their greater predisposition to audiogenic epilepsy (83% in PM+ versus 40% in PM- rats). On the contrary, PM- rats were found to be more prone to freezing (61% in PV- versus 11% in PM+). In PM+ rats, noradrenaline and serotonin contents were decreased in hypothalamus (as compared to PM- and control Wistar stain), whereas in PM- rats, serotonin content was increased in striatum, hypothalamus and midbrain as compared to control strains.
Aleksina
T A
TA
Prokudina
O I
OI
Riazanova
M A
MA
Ukolova
T N
TN
Barykina
N N
NN
Kolpakov
V G
VG
D000161:Acoustic Stimulation; D000818:Animals; D001522:Behavior, Animal; D001921:Brain / Q000033:anatomy & histology / Q000378:metabolism*; D001947:Breeding; D020195:Epilepsy, Reflex / Q000235:genetics / Q000503:physiopathology*; D008297:Male; D009638:Norepinephrine / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains; D017208:Rats, Wistar; D012701:Serotonin / Q000378:metabolism*; D013239:Stereotyped Behavior
D012701:Serotonin; D009638:Norepinephrine