title: [Comparative study on quality of Flos Lonicerae between geo-authentic and non-authentic producing areas].
abstract: OBJECTIVE
  To compare the quality of Flos Lonicerae between different producing areas.
  
  
  METHODS
  ICP-AES, UV and HPLC were used to determine the contents of trace elements, chlorogenic acid, total flavonoids, five iridoid glucosides, hederagenin, and oleanolic acid. SAS software system was used to perform data and cluster analyses.
  
  
  RESULTS
  The results showed that the geo-authentic crude drug was lower in the contents of Cr and Pb but higher in the contents of chlorogenic acid, total flavonoids, five iridoid glucosides, hederagenin, and oleanolic acid than the non-authentic crude drug.
  
  
  CONCLUSIONS
  The geo-authentic crude drug of Flos Lonicerae is better in quality than the non-authentic crude drug based on the modern chemical analyses, which confirms the validity of traditional geo-based classification.
authors.affiliation: Department of Pharmacognosy, China Pharmaceutical University, Nanjing 210038, China.
authors.forename: Zhong-Yi
authors.initials: ZY
authors.lastname: Zhang
authors.forename: Ping
authors.initials: P
authors.lastname: Li
authors.forename: Hui-Jun
authors.initials: HJ
authors.lastname: Li
authors.forename: Xiao-Fang
authors.initials: XF
authors.lastname: Xu
authors.forename: Jun
authors.initials: J
authors.lastname: Chen
authors.forename: Yong-Suo
authors.initials: YS
authors.lastname: Liu
authors.forename: Hui-Na
authors.initials: HN
authors.lastname: Zhao
mesh_terms: D002681:China; D002726:Chlorogenic Acid / Q000032:analysis*; D002857:Chromium / Q000032:analysis; D016000:Cluster Analysis; D017753:Ecosystem; D005419:Flavonoids / Q000032:analysis*; D035264:Flowers / Q000737:chemistry; D007854:Lead / Q000032:analysis; D031239:Lonicera / Q000737:chemistry* / Q000254:growth & development; D009828:Oleanolic Acid / Q000031:analogs & derivatives / Q000032:analysis; D010946:Plants, Medicinal / Q000737:chemistry* / Q000254:growth & development; D011786:Quality Control; D014131:Trace Elements / Q000032:analysis* / Q000592:standards
chemical_list: D005419:Flavonoids; D014131:Trace Elements; D002857:Chromium; D007854:Lead; D002726:Chlorogenic Acid; D009828:Oleanolic Acid; C025763:hederagenin