title: [FDG-PET-CT based imaging of retropharyngeal lymph nodes with its impact on radiotherapy].
abstract: BACKGROUND
  In about 20% there is an involvement of the retropharyngeal lymph nodes in patients with locally advanced carcinoma of the hypopharynx and cervical esophagus. A case report should demonstrate the diagnostic and therapeutic impact of FDG-PET/CT in the radiotherapeutic management of a locally advanced carcinoma of the hypopharynx in special consideration of the RPLN.
  
  
  METHODS
  A pretherapeutic FDG-PET/CT was performed with the patient fixed in the radiotherapy mask in order to integrate the anatomic and metabolic information into the radiotherapy planning system by an exact matching of the data.
  
  
  RESULTS
  Only the FDG-PET could detect a retropharyngeal lymph node involvement (RPLN) by an intensive glucose utilisation with a consecutive modification of the target volume and dose increase in this region.
  
  
  CONCLUSIONS
  This case report demonstrates that FDG-PET/CT facilitates the imaging of metabolic active and otherwise hardly detectable lymph nodes in locally advanced head and neck cancer with consequences on target volume definition and dose application in radiotherapy.
authors.affiliation: Klinik und Poliklinik für Strahlentherapie der Universität Regensburg, Regensburg. barbara.dietl@klinik.uni-regensburg.de
authors.forename: B
authors.initials: B
authors.lastname: Dietl
authors.forename: J
authors.initials: J
authors.lastname: Marienhagen
authors.forename: T
authors.initials: T
authors.lastname: Murthum
authors.forename: O
authors.initials: O
authors.lastname: Kölbl
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use; D001786:Blood Glucose / Q000378:metabolism; D002294:Carcinoma, Squamous Cell / Q000188:drug therapy / Q000473:pathology / Q000532:radiotherapy*; D017024:Chemotherapy, Adjuvant; D002945:Cisplatin / Q000627:therapeutic use; D003131:Combined Modality Therapy; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D007012:Hypopharyngeal Neoplasms / Q000188:drug therapy / Q000473:pathology / Q000532:radiotherapy*; D007091:Image Processing, Computer-Assisted; D015182:Lymphatic Irradiation; D008207:Lymphatic Metastasis / Q000473:pathology / Q000532:radiotherapy*; D008875:Middle Aged; D009367:Neoplasm Staging; D049268:Positron-Emission Tomography; D011879:Radiotherapy Dosage; D011880:Radiotherapy Planning, Computer-Assisted; D014057:Tomography, X-Ray Computed
chemical_list: D000970:Antineoplastic Agents; D001786:Blood Glucose; D019788:Fluorodeoxyglucose F18; D002945:Cisplatin