title: Ultrasound-guided breast biopsy using a 10-gauge self-contained vacuum-assisted device.
abstract: The purpose of this study was to evaluate the diagnostic value of a self-contained battery-driven vacuum-assisted breast biopsy (VABB) system for the sampling of breast masses under ultrasound guidance. Sixty-five patients with 70 lesions underwent percutaneous 10-gauge ultrasound-guided VABB using the coaxial technique. In 38 lesions, subsequent surgery and comparison of histology was performed. The remaining 32 cases were followed-up and defined as true negative after a cancer-free interval of 24 months. VABB revealed malignant histology in 28 (40%) cases. Twenty-four malignancies were confirmed after surgery. Four invasive cancers verified in VABB were not found during surgery because they were completely removed, as proved by a disease-free interval of 24 months. One cancer missed in ultrasound-guided VABB due to its small size was successfully diagnosed with stereotactic VABB and thus turned out to be false negative, resulting in an overall sensitivity of 96.6%. Forty-one patients were free of cancer during the follow-up period of at least 24 months. In conclusion, the self-contained VABB device is well suited for ultrasound-guided breast biopsies.
authors.affiliation: Institute of Diagnostic and Interventional Radiology, Friedrich Schiller University Hospital Jena, Erlanger Allee 101, 07747, Jena, Germany.
authors.forename: Tibor
authors.initials: T
authors.lastname: Vag
authors.forename: Stefan O R
authors.initials: SO
authors.lastname: Pfleiderer
authors.forename: Joachim
authors.initials: J
authors.lastname: Böttcher
authors.forename: Susanne
authors.initials: S
authors.lastname: Wurdinger
authors.forename: Mieczyslaw
authors.initials: M
authors.lastname: Gajda
authors.forename: Oumar
authors.initials: O
authors.lastname: Camara
authors.forename: Werner A
authors.initials: WA
authors.lastname: Kaiser
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001707:Biopsy, Needle / Q000295:instrumentation*; D001943:Breast Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D011237:Predictive Value of Tests; D011446:Prospective Studies; D012680:Sensitivity and Specificity; D018084:Ultrasonography, Interventional; D016217:Ultrasonography, Mammary; D014618:Vacuum