[Enzymatic activity, slime production and antifungal agent sensitivity of Candida sp].
Abilith of Candida spp to secrete extracellular enzymes and slime has been associated as pathogenicity factors. Out of a total of 37 strains of Candida sp, 100% were proteinase producers, 83.8% were phospholipase producers, 64.9% were slime producers and 100% were sensitive to fluconazole and itraconazole. Seventeen typings (enzymes/slime) were found. This methodology presented a good discrimination rate (D=0.93) and could be used for phenotypic characterization of yeasts.
Silva
Jaqueline Otero
JO
Laboratório I de Ribeirão Preto, Instituto Adolfo Lutz, Ribeirão Preto, SP. jaquelineos@ig.com.br
Ferreira
Joseane Cristina
JC
Candido
Regina Célia
RC
D000935:Antifungal Agents / Q000494:pharmacology*; D018441:Biofilms / Q000187:drug effects / Q000254:growth & development*; D002175:Candida / Q000187:drug effects / Q000201:enzymology / Q000502:physiology*; D015725:Fluconazole / Q000494:pharmacology; D006801:Humans; D017964:Itraconazole / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D010447:Peptide Hydrolases / Q000187:drug effects / Q000378:metabolism*; D010740:Phospholipases / Q000187:drug effects / Q000378:metabolism*
D000935:Antifungal Agents; D017964:Itraconazole; D015725:Fluconazole; D010740:Phospholipases; D010447:Peptide Hydrolases