title: Restenosis developing over one year after implantation with a sirolimus-eluting stent: two case reports.
abstract: A 68-year-old man with familial hypercholesterolemia developed effort angina and received a sirolimus-eluting stent (SES) to treat 99% stenosis in segment 6 of the left anterior descending coronary artery in January 2005. A further stent was implanted 14 months later to treat 99% restenosis at the proximal stent edge. A 66-year-old man with diabetes developed acute anterior myocardial infarction and underwent SES implantation to treat 90% stenosis in segment 4 atrioventricular node artery branch of the right coronary artery in April 2006. Heart failure developed 14 months later. Another stent was implanted to treat 100% obstructive stenosis of the proximal stent site. Late stent restenosis may occur over 1 year after SES implantation, so longer follow-up is required compared to bare metal stent.
authors.affiliation: Division of Cardiology, Tokyo Kita Social Insurance Hospital, Akabanedai 4-17-56, Kita-ku, Tokyo 110-3377. taku-iku@fa2.so-net.ne.jp
authors.forename: Takuji
authors.initials: T
authors.lastname: Katayama
authors.forename: Nobuhiko
authors.initials: N
authors.lastname: Ogata
authors.forename: Yoshio
authors.initials: Y
authors.lastname: Tsuruya
mesh_terms: D000368:Aged; D000787:Angina Pectoris / Q000628:therapy; D003324:Coronary Artery Disease / Q000628:therapy; D023903:Coronary Restenosis / Q000209:etiology*; D006801:Humans; D006938:Hyperlipoproteinemia Type II / Q000150:complications; D008297:Male; D009203:Myocardial Infarction / Q000628:therapy; D020123:Sirolimus / Q000008:administration & dosage*; D015607:Stents / Q000009:adverse effects*
chemical_list: D020123:Sirolimus