title: Synthesis and applications of a novel polymer-supported EEDQ reagent.
abstract: A simple synthetic protocol for a novel polymer-supported EEDQ reagent is reported. This reagent promotes solution-phase amide bond formation without any additives or base, as well as the selective coupling of aliphatic amines with acids in the presence of aromatic amines.
authors.affiliation: Early Discovery Chemistry, Bristol-Myers Squibb R&D, 5 Research Parkway, Wallingford, Connecticut 06492-7600, USA. ramesh.kakarla@bms.com
authors.forename: Ramesh
authors.initials: R
authors.lastname: Kakarla
authors.forename: Guo
authors.initials: G
authors.lastname: Li
authors.forename: Samuel W
authors.initials: SW
authors.lastname: Gerritz
mesh_terms: D007202:Indicators and Reagents / Q000138:chemical synthesis*; D011108:Polymers / Q000737:chemistry*; D011804:Quinolines / Q000138:chemical synthesis*
chemical_list: D007202:Indicators and Reagents; D011108:Polymers; D011804:Quinolines; C000470:EEDQ