title: An iron carbonyl approach to the influenza neuraminidase inhibitor oseltamivir.
abstract: A novel synthetic route towards oseltamivir, an influenza neuraminidase inhibitor, has been achieved employing a cationic iron carbonyl complex, providing an alternate pathway with the potential to access diverse analogues.
authors.affiliation: Organic Chemistry, Department of Chemical and Biological Engineering, Chalmers University of Technology, 41296 Göteborg, Sweden.
authors.forename: Karen M
authors.initials: KM
authors.lastname: Bromfield
authors.forename: Henrik
authors.initials: H
authors.lastname: Gradén
authors.forename: Daniel P
authors.initials: DP
authors.lastname: Hagberg
authors.forename: Thomas
authors.initials: T
authors.lastname: Olsson
authors.forename: Nina
authors.initials: N
authors.lastname: Kann
mesh_terms: D000998:Antiviral Agents / Q000138:chemical synthesis*; D002248:Carbon Monoxide / Q000737:chemistry; D053138:Cyclohexenes / Q000737:chemistry; D004791:Enzyme Inhibitors / Q000138:chemical synthesis; D007501:Iron / Q000737:chemistry*; D009439:Neuraminidase / Q000037:antagonists & inhibitors*; D009942:Organometallic Compounds / Q000737:chemistry*; D053139:Oseltamivir / Q000138:chemical synthesis*
chemical_list: D000998:Antiviral Agents; D053138:Cyclohexenes; D004791:Enzyme Inhibitors; D009942:Organometallic Compounds; D053139:Oseltamivir; D002248:Carbon Monoxide; D007501:Iron; D009439:Neuraminidase