title: [Statistical notes. Statistical significance and clinical relevance: are they the two sides of the same medal?].
abstract: The aim of this statistical note is to draw the attention of the cardiologists to the aspects pertinent to the clinical relevance of the result of a clinical controlled randomized trial. The difference between clinical relevance and statistical significance is shown by using the results of GISSI and GUSTO III clinical controlled randomized trials.
authors.affiliation: Istituto di Statistica Medica e Biometria G.A. Maccacaro, Cascina Rosa, Università degli Studi, Milano. ettore.marubini@unimi.it
authors.forename: Ettore
authors.initials: E
authors.lastname: Marubini
authors.forename: Bruno Mario
authors.initials: BM
authors.lastname: Cesana
mesh_terms: D016001:Confidence Intervals; D006801:Humans; D016032:Randomized Controlled Trials as Topic; D013223:Statistics as Topic