title: Predictors of target lesion revascularization and documented stent thrombosis beyond 30 days after sirolimus-eluting stent implantation: retrospective analysis in consecutive 1,070 angiographic follow-up lesions.
abstract: BACKGROUND
  Outcomes after sirolimus-eluting stent (SES: Cypher) implantation remained to be elucidated in Japan.
  
  
  RESULTS
  Among 1,070 consecutive angiographic follow-up lesions, 99 lesions underwent target lesion revascularization (TLR) with in-stent restenosis (ISR). Retrospective estimation by multivariate analysis including 50 variables showed that the ostiums of right coronary and left circumflex arteries, hemodialysis, calcification, non-direct stenting, ISR of SES, and non-eccentric lesion were the predictors of TLR. There was no documented late stent thrombosis (LST) among 2,166 lesions and very LST (VLST) among 1,423 lesions.
  
  
  CONCLUSIONS
  Further revises are needed to implant SES to these predictive lesions. LST and VLST were very rare.
authors.affiliation: Division of Cardiology, Saitama Prefecture Cardiovascular and Respiratory Center, Kumagaya, Japan. a1079081@pref.saitama.jp
authors.forename: Makoto
authors.initials: M
authors.lastname: Mutoh
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Ishikawa
authors.forename: Toshio
authors.initials: T
authors.lastname: Hasuda
authors.forename: Hisayuki
authors.initials: H
authors.lastname: Okada
authors.forename: Akira
authors.initials: A
authors.lastname: Endo
authors.forename: Satoru
authors.initials: S
authors.lastname: Miyanaga
authors.forename: Michiaki
authors.initials: M
authors.lastname: Higashitani
authors.forename: Yosuke
authors.initials: Y
authors.lastname: Nakano
authors.forename: Takeyuki
authors.initials: T
authors.lastname: Kubota
authors.forename: Koutarou
authors.initials: K
authors.lastname: Nakata
authors.forename: Tomohisa
authors.initials: T
authors.lastname: Nagoshi
authors.forename: Mayuri
authors.initials: M
authors.lastname: Hayashi
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Sakamoto
authors.forename: Masato
authors.initials: M
authors.lastname: Oota
authors.forename: Kamon
authors.initials: K
authors.lastname: Imai
authors.forename: Seibu
authors.initials: S
authors.lastname: Mochizuki
mesh_terms: D017023:Coronary Angiography; D005260:Female; D006083:Graft Occlusion, Vascular; D006801:Humans; D008297:Male; D009204:Myocardial Revascularization; D011237:Predictive Value of Tests; D011379:Prognosis; D012189:Retrospective Studies; D020123:Sirolimus / Q000008:administration & dosage*; D015607:Stents / Q000009:adverse effects*; D013927:Thrombosis / Q000209:etiology*
chemical_list: D020123:Sirolimus