title: [Therapeutic effect of liver transplantation on acute liver failure].
abstract: OBJECTIVE
  To evaluate the short-term and long-term outcomes of emergent liver transplantation recipients with acute liver failure and to identify factors that influenced these outcomes.
  
  
  METHODS
  318 consecutive patients who underwent liver transplantations between January 2001 and December 2004 were analyzed retrospectively (all the cases were followed up to December 2005). According to UNOS grading scale, all recipients preoperative status were evaluated. 54 patients were acute liver failure (Group I, UNOS 1 and 2A), and the other 264 cases were chronic liver diseases (Group II, UNOS 2B and 3). The postoperative effects in different groups were compared, including the survival rates, incidences of complications, rates and causes of retransplantation, rates and causes of death.
  
  
  RESULTS
  Comparing UNOS2B/3 to UNOS1/2A, the perioperative mortality were 3.7%; 22.6%, the rate of complications 16.7%; 55.6%, 1 year survival rate 91.3%; 74.1%, 3 year survival rate 86.4%; 68.5%, the retransplantation rate 1.1%; 18.5% respectively.
  
  
  CONCLUSIONS
  Since the technique of liver transplant is very advanced, the effect of surgery is mainly depended on the function of liver and other organs in patients. The recipients with UNOS2B/3 have better short-term and long-term outcomes as comparing to UNOS1/2A. In addition, the recipients with UNOS1/2A are burdened with much higher mortality.
authors.affiliation: General surgery department of the first people's hospital affiliated to Shanghai Jiaotong University, Shanghai 200080, China.
authors.forename: Zhi-hai
authors.initials: ZH
authors.lastname: Peng
authors.forename: Tong-hai
authors.initials: TH
authors.lastname: Xing
authors.forename: De-jian
authors.initials: DJ
authors.lastname: Dai
authors.forename: Guo-qing
authors.initials: GQ
authors.lastname: Chen
authors.forename: Jun-ming
authors.initials: JM
authors.lastname: Xu
authors.forename: Lin
authors.initials: L
authors.lastname: Zhong
authors.forename: Tao
authors.initials: T
authors.lastname: Li
authors.forename: Xing
authors.initials: X
authors.lastname: Sun
authors.forename: Shu-yun
authors.initials: SY
authors.lastname: Wang
authors.forename: Zhao-wen
authors.initials: ZW
authors.lastname: Wang
mesh_terms: D002423:Cause of Death; D005260:Female; D005500:Follow-Up Studies; D006085:Graft Survival; D006801:Humans; D017114:Liver Failure, Acute / Q000401:mortality / Q000601:surgery*; D016031:Liver Transplantation; D008297:Male; D012092:Replantation; D012189:Retrospective Studies; D015996:Survival Rate