title: [A case report on canceration of proliferative verrucous leukoplakia].
abstract: Proliferative verrucous leukoplakia (PVL) is a particular form of oral leukoplakia clinically characterized by chronic proliferation, multiple occurrence, and intractability. It is seen mostly among elderly women and often involves bucca, palate, gingiva and tongue. Its canceration rate is very high. This article reports a case of a middle-aged woman with progressive PVL which became focally malignant who complained about buccal and palatal exophytic white patches, and discusses the possible pathogenic mechanism, diagnosis, treatment, prognosis of PVL and differentiation between PVL and other types of oral leukoplakia by way of reviewing relevant literature.
authors.affiliation: Dept. of Oral Medicine, West China College of Stomatology, Sichuan University, Chengdu 610041, China.
authors.forename: Lin
authors.initials: L
authors.lastname: Ge
authors.forename: Hong-Mei
authors.initials: HM
authors.lastname: Zhou
authors.forename: Xin
authors.initials: X
authors.lastname: Zeng
authors.forename: Lan-Yan
authors.initials: LY
authors.lastname: Wu
authors.forename: Mei
authors.initials: M
authors.lastname: Lin
mesh_terms: D000368:Aged; D002294:Carcinoma, Squamous Cell; D002454:Cell Differentiation; D002471:Cell Transformation, Neoplastic; D005260:Female; D005881:Gingiva; D006801:Humans; D007972:Leukoplakia, Oral; D008875:Middle Aged; D014059:Tongue