title: Fam-Ti catalyzed enantioselective alkynylation of aldehydes.
abstract: Ferrocenyl-substituted aziridinylmethanol (Fam-1) has been used as a chiral catalyst with titanium for enantioselective alkynylation of aromatic, heteroaromatic, aliphatic, and alpha,beta-unsaturated aldehydes to give the corresponding propargylic alcohols in up to 96% yield and 96% ee. The ligand can be prepared easily and recycled.
authors.affiliation: Department of Chemistry, Middle East Technical University, 06531 Ankara, Turkey.
authors.forename: Hasan
authors.initials: H
authors.lastname: Koyuncu
authors.forename: Ozdemir
authors.initials: O
authors.lastname: Dogan