Severe Toxoplasma gondii I/III recombinant-genotype encephalitis in a human immunodeficiency virus patient.
The reactivation of an uncommon type I/III recombinant-genotype Toxoplasma gondii strain resulted in unusually severe encephalitis and chorioretinitis associated with a cerebral salt wasting syndrome in an African human immunodeficiency virus patient. This observation suggests an influence of the parasite genotype on disease expression in immunocompromised patients.
Genot
Séverine
S
Service des Maladies Infectieuses, Hôpital de la Conception, France.
Franck
Jacqueline
J
Forel
Jean-Marie
JM
Rebaudet
Stanislas
S
Ajzenberg
Daniel
D
de Paula
Andre Maues
AM
Dardé
Marie-Laure
ML
Stein
Andreas
A
Ranque
Stéphane
S
D000818:Animals; D000981:Antiprotozoal Agents / Q000627:therapeutic use; D001921:Brain / Q000469:parasitology / Q000473:pathology; D002825:Chorioretinitis / Q000188:drug therapy / Q000469:parasitology; D016054:DNA, Protozoan / Q000235:genetics*; D005838:Genotype; D015658:HIV Infections / Q000150:complications*; D006801:Humans; D008297:Male; D008875:Middle Aged; D014122:Toxoplasma / Q000145:classification* / Q000235:genetics* / Q000302:isolation & purification; D016781:Toxoplasmosis, Cerebral / Q000188:drug therapy / Q000469:parasitology*
D000981:Antiprotozoal Agents; D016054:DNA, Protozoan