title: Carcinosarcoma de novo of the parotid gland.
abstract: Only 29 cases of salivary gland carcinosarcoma de novo have been described in the English-language literature. We present a new case of parotid gland carcinosarcoma de novo and discuss diagnostic and treatment modalities of this pathologic entity. Our patient underwent total parotidectomy with facial nerve preservation, chemotherapy, and radiotherapy. At 26-month follow-up, the patient presented no evidence of recurrence. One-third of the cases of salivary carcinosarcoma de novo died of the disease after a median period of 10 months. Although the number of cases is limited, the combination of radical surgical excision and radiotherapy seems currently the treatment of choice.
authors.affiliation: Department of Medical and Surgical Specialties, Section of Otolaryngology, University of Padova, Padova, Italy. claustaffieri@virgilio.it
authors.forename: Claudia
authors.initials: C
authors.lastname: Staffieri
authors.forename: Gino
authors.initials: G
authors.lastname: Marioni
authors.forename: Silvia Maria
authors.initials: SM
authors.lastname: Ferraro
authors.forename: Filippo
authors.initials: F
authors.lastname: Marino
authors.forename: Alberto
authors.initials: A
authors.lastname: Staffieri
mesh_terms: D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002296:Carcinosarcoma / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D002648:Child; D005260:Female; D006801:Humans; D010307:Parotid Neoplasms / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D035583:Rare Diseases