Multi-link Vision and MiniVision stent registry in Asian patients with coronary artery disease: a prospective, multi-center study.
BACKGROUND
Recent studies have showed that the fine mesh stents are associated with a significant reduction in both clinical and angiographic re-stenosis of the coronary arteries. To maintain a very satisfactory radio-opacity using the stents, Guidant of the USA has designed a new type of bare metal stents (BMS)-Multi-link (ML) Vision/ML MiniVision stents. The clinical outcomes of Asian patients with coronary artery disease (CAD) after implanting the Multi-link Vision or MiniVision stent were investigated in this study.


METHODS
An observational, prospective, multi-center, non-randomized post marketing registry was conducted to demonstrate the efficacy of the BMS-ML Vision/ML MiniVision stents. The primary end point of the registry was clinical target lesion revascularization (TLR) at a 6-month follow-up. The major secondary end points included the rate of major adverse cardiac events (MACE) and serious adverse events (SAE) in hospital and at 6 months; and the rate of clinical TLR as a function of the type of angina. A total of 429 Asian people with 449 lesions from 14 centers were selected for this study. The average reference diameter of the lesions was (3.0 +/- 0.5) mm, and the mean length was (15.7 +/- 5.0) mm.


RESULTS
The successful rate of the procedure was 99.3%. Twenty-five percent of the lesions were treated by direct stenting without pre-dilation. Eighty-six percent of the lesions were implanted with ML Vision stent. After the 6-month follow-up, the rate of clinical TLR was 1.4%. The MACE, SAE and target vessel revascularization (TVR) were 6.8%, 3.5% and 1.4% respectively.


CONCLUSIONS
The current registry showed the excellent 6-month clinical outcomes of ML Vision/ML MiniVision stents in Asian patients with CAD.
Xu
Ya-Wei
YW
Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan 430063, China.
Wei
Yi-Dong
YD
Tang
Kai
K
Chen
Yan-Qing
YQ
Li
Wei-Ming
WM
Yu
Xue-Jing
XJ
Qin
Yong-Wen
YW
Qi
Guo-Xian
GX
Qu
Peng
P
Hou
Yu-Qing
YQ
Jain
Ashok
A
Grant
Parvez
P
Ramesh
Gudapati
G
Ramesh
Basavappa
B
Piamsomboon
Chumpol
C
Kuanprasert
Srun
S
Gwon
Hyeon-Cheol
HC
Cho
Yoon Haeng
YH
Kamar
Haizal Haroon
HH
Huang
Cong-Xin
CX
D000368:Aged; D015906:Angioplasty, Balloon, Coronary / Q000379:methods*; D002858:Chromium Alloys; D003327:Coronary Disease / Q000628:therapy*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012042:Registries; D015607:Stents
D002858:Chromium Alloys