title: [The aetiology of generalized alopecia in young calves].
abstract: The objective of this study was to test for correlations between alopecia and ruminal drinking in young calves. 331 calves up to an age of 31 days were tested for evidence of generalized hair loss daily during their stay in the clinic. Incidence of diarrhoea and the results of ruminal fluid and blood analysis were compared between the groups with and without alopecia. Calves with alopecia showed a significantly higher incidence of diarrhoea and of ruminal acidosis persisting for at least 24 hours. Blood analysis revealed significant differences in degree of acidosis, in concentrations of D-lactate, urea, and creatinine in serum as well as in the activities of glutathione peroxidase, aspartate amino transferase, and creatine kinase. Alopecia in calves is correlated to longer periods of diseases, which are known to be accompanied by the production of D-lactate in the gastrointestinal tract, such as diarrhoea and ruminal drinking. The question, whether alopecia is due to formation of toxic substances or to deficiency of essential substances can not be answered.
authors.affiliation: Lehrstuhl für Innere Medizin und Chirurgie der Wiederkäuer an der Klinik für Wiederkäuer der Ludwig-Maximilians-Universität München. i.lorenz@lmu.de
authors.forename: I
authors.initials: I
authors.lastname: Lorenz
authors.forename: S
authors.initials: S
authors.lastname: Mayr
authors.forename: G
authors.initials: G
authors.lastname: Rademacher
authors.forename: W
authors.initials: W
authors.lastname: Klee
mesh_terms: D000505:Alopecia / Q000209:etiology / Q000503:physiopathology / Q000662:veterinary*; D000818:Animals; D002417:Cattle; D002418:Cattle Diseases / Q000209:etiology* / Q000503:physiopathology; D003967:Diarrhea / Q000503:physiopathology / Q000662:veterinary; D005260:Female; D005766:Gastrointestinal Contents / Q000737:chemistry*; D006863:Hydrogen-Ion Concentration; D008297:Male; D012417:Rumen / Q000737:chemistry* / Q000378:metabolism; D013272:Stomach Diseases / Q000150:complications / Q000503:physiopathology / Q000662:veterinary*