title: In situ effect of strontium toothpaste on artificially decalcified human enamel.
abstract: The aim of this study was to measure the strontium levels in surface and subsurface artificially decalcified enamel exposed in situ to a strontium-supplemented toothpaste. Twenty healthy premolar teeth extracted for orthodontic reasons were cut into blocks and demineralized. The samples were cemented to the teeth of six volunteers who brushed with a hydroxyapatite (HAP) and HAP strontium-supplemented toothpaste for 3 and 6 mo. The strontium content in the enamel surface and in the lateral wall of the enamel samples was evaluated using energy-dispersive spectrometry microanalysis. After 3 mo, the strontium content in the enamel surface increased significantly compared to baseline values. On the lateral enamel surfaces, the strontium level was the same in all of the layers after 6 mo and was higher than the level observed after 3 mo. Regular toothbrushing with a strontium-supplemented toothpaste has been found to increase the strontium content in the exposed enamel, which can be an advantage in the prevention of cariogenesis.
authors.affiliation: Department of Conservative Dentistry and Periodontology, 60-812 Poznan, Poland.
authors.forename: Anna
authors.initials: A
authors.lastname: Surdacka
authors.forename: Janina
authors.initials: J
authors.lastname: Stopa
authors.forename: Lech
authors.initials: L
authors.lastname: Torlinski
mesh_terms: D000293:Adolescent; D002327:Cariostatic Agents; D002648:Child; D003731:Dental Caries / Q000517:prevention & control; D003743:Dental Enamel / Q000187:drug effects*; D017886:Durapatite / Q000737:chemistry; D005260:Female; D006801:Humans; D008297:Male; D008956:Models, Chemical; D013324:Strontium / Q000008:administration & dosage* / Q000737:chemistry; D013997:Time Factors; D014099:Toothbrushing; D014100:Toothpastes / Q000737:chemistry*
chemical_list: D002327:Cariostatic Agents; D014100:Toothpastes; D017886:Durapatite; D013324:Strontium