title: [Endoscopic submucosal dissection for early gastric cancer and gastric adenoma].
abstract: OBJECTIVE
  Endoscopic Submucosal Dissection (ESD) is a new endoscopic mucosal resection (EMR) technique which enables en bloc resection even in large and depressed lesions. The aims of this study were to assess the therapeutic efficacy and the safety of ESD in gastric adenoma and in early gastric cancer (EGC).
  
  
  METHODS
  We analyzed 101 lesions in 101 patients. ESD with insulated-tipped (IT) knife were performed in 52 adenomas and 49 EGCs from January 2003 to December 2005 in Dong-A University Hospital.
  
  
  RESULTS
  The mean size of the lesion was 2.58 cm (0.7-4.5 cm). En bloc resection rate was 90.1% which was influenced by size (p0.05). Complete resection rate was 83.2% even in large or in malignant tumors (p0.05). Bleeding after ESD occurred in 41.6%. Tumor recurrence rate was 2.0%.
  
  
  CONCLUSIONS
  ESD with IT knife is effective for the treatment of EGC and gastric adenoma even in large or in malignant lesions without definite increased risk of complications.
authors.affiliation: Department of Internal Medicine, Dong-A University College of Medicine, Busan, Korea.
authors.forename: Jin Seok
authors.initials: JS
authors.lastname: Jang
authors.forename: Eun Joo
authors.initials: EJ
authors.lastname: Lee
authors.forename: Sung Wook
authors.initials: SW
authors.lastname: Lee
authors.forename: Jong Hun
authors.initials: JH
authors.lastname: Lee
authors.forename: Myung Hwan
authors.initials: MH
authors.lastname: Roh
authors.forename: Sang Young
authors.initials: SY
authors.lastname: Han
authors.forename: Seok Reyol
authors.initials: SR
authors.lastname: Choi
authors.forename: Jin Sook
authors.initials: JS
authors.lastname: Jeong
mesh_terms: D000236:Adenoma / Q000473:pathology / Q000601:surgery*; D000328:Adult; D000368:Aged; D004210:Dissection / Q000295:instrumentation; D005260:Female; D005753:Gastric Mucosa / Q000473:pathology / Q000601:surgery*; D005773:Gastroscopy; D006801:Humans; D008297:Male; D008875:Middle Aged; D019060:Minimally Invasive Surgical Procedures; D009367:Neoplasm Staging; D012189:Retrospective Studies; D013274:Stomach Neoplasms / Q000473:pathology / Q000601:surgery*