Adenoid cystic carcinoma of the lung: interest of 18FDG PET/CT in the management of an atypical presentation.
Adenoid cystic carcinoma (ACC) is a common head and neck tumor originating from salivary glands but that can also exceptionally develop in the trachea and major bronchi. ACC is generally considered as a slow-growing, low-grade malignancy with prolonged clinical course. Metastases are very unusual and recurrences are more often local. Treatment for localized ACC is surgery. We here report for the first time a case of lung ACC with a synchronous liver metastasis proved by biopsy. Moreover, we report the interest of performing a 18FDG PET-CT as both primary tumor and liver metastasis presented an intense FDG uptake. The specificity of the liver 18FDG uptake was confirmed by Glut-1 positive immunostaining. We propose that 18FDG PET-CT should be considered in the initial staging of lung ACC in selected patients.
Campistron
Marion
M
Service de Pneumologie-Allergologie, Clinique des Voies Respiratoires, Hôpital Larrey, Chemin de Pouvourville, 31059 Toulouse Cedex, France.
Rouquette
Isabelle
I
Courbon
Fréderick
F
Chabbert
Valérie
V
Rochaix
Philippe
P
Prévot
Grégoire
G
Laroumagne
Sophie
S
Têtu
Laurent
L
Didier
Alain
A
Mazières
Julien
J
D000368:Aged; D000369:Aged, 80 and over; D003528:Carcinoma, Adenoid Cystic / Q000000981:diagnostic imaging* / Q000473:pathology; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008175:Lung Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D049268:Positron-Emission Tomography; D014057:Tomography, X-Ray Computed
D019788:Fluorodeoxyglucose F18