title: [Corneal edema and systemic NSAIDs].
abstract: BACKGROUND
  We report a case of a transient corneal edema related to systemic NSAID treatment.
  
  
  METHODS
  A 48-year-old woman treated with a systemic NSAID [piroxicam B-cyclodextrin (Brexin) and naproxen (Apranax)] presented with a corneal edema and a transient decrease in visual acuity for a period of 24 h. No ocular etiology was found to explain this corneal edema. Another treatment with Apranax was follow by another corneal edema.
  
  
  CONCLUSIONS
  Corneal edema could be related to systemic NSAID treatment.
authors.affiliation: Service d'Ophtalmologie CHU de Bicêtre, Le Kremlin Bicêtre Cedex, France.
authors.forename: H
authors.initials: H
authors.lastname: Offret
authors.forename: M
authors.initials: M
authors.lastname: Labetoulle
authors.forename: O
authors.initials: O
authors.lastname: Offret
mesh_terms: D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects* / Q000627:therapeutic use; D015715:Corneal Edema / Q000139:chemically induced*; D005260:Female; D006801:Humans; D007405:Intervertebral Disc Displacement / Q000188:drug therapy; D008159:Lumbar Vertebrae; D008875:Middle Aged; D009288:Naproxen / Q000009:adverse effects* / Q000627:therapeutic use; D010894:Piroxicam / Q000009:adverse effects* / Q000627:therapeutic use; D012008:Recurrence; D047392:beta-Cyclodextrins / Q000009:adverse effects* / Q000627:therapeutic use
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D047392:beta-Cyclodextrins; D010894:Piroxicam; D009288:Naproxen; C061072:piroxicam-beta-cyclodextrin