title: [Postoperative symptoms and life quality assessment of chronic rhinosinusitis patients received endoscopic sinus surgery].
abstract: OBJECTIVE
  To implore the positive effects of endoscopic sinus surgery on the symptoms and quality of life (QOL) of patients with chronic rhinosinusitis (CRS) and their changing regularity of symptoms and QOL.
  
  
  METHODS
  A prospective, randomized and controlled trial was conducted to survey symptoms and QOL status of 120 CRS patients undergoing endoscopic sinus surgery, in contrast to that of 200 healthy individuals passing health examination, at the baseline and at 3- and 6-months postoperatively by visual analog score (VAS) symptom instrument and QOL instruments including medical outcome study short-form 36-items health survey (SF-36) and sino-nasal outcome test-20 (SNOT-20).
  
  
  RESULTS
  In the 3 months follow-up settings, total of individual symptom severity scores and global symptom severity scores of VAS, such domains as role physical and general health of SF-36 and total of the 20 items scores and the most important 5-item scores of SNOT-20 all began to get better markedly (P < 0.05); in the 3-6 months follow-up settings, the indices above stayed fixed (P > 0.05); and in the 6-months follow-up settings, indices of symptoms and QOL status entirely improved from the baseline, with SF-36 showing no scoring difference between CRS patients and healthy individuals, whereas VAS showed that abnormal nasal drainage and decreased sense of smell were still left and SNOT-20 showed that abnormal nasal drainage and lack of good sleep left, inferior to that of healthy objects significantly (P < 0.05).
  
  
  CONCLUSIONS
  On the whole CRS patients undergoing endoscopic sinus surgery recover symptomatically and come back to normal level of QOL status at the 6 months postoperatively, but such significant problems as abnormal nasal drainage, decreased sense of smell and lack of good sleep still remain and need to be treated.
authors.affiliation: Otorhinolaryngology Hospital and Institute of the First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, China.
authors.forename: Ke-jun
authors.initials: KJ
authors.lastname: Zuo
authors.forename: Geng
authors.initials: G
authors.lastname: Xu
authors.forename: De-yun
authors.initials: DY
authors.lastname: Wang
authors.forename: Jian-bo
authors.initials: JB
authors.lastname: Shi
authors.forename: Wei-ping
authors.initials: WP
authors.lastname: Wen
authors.forename: Yun-ping
authors.initials: YP
authors.lastname: Fan
authors.forename: Hong-yan
authors.initials: HY
authors.lastname: Jiang
authors.forename: He-xin
authors.initials: HX
authors.lastname: Chen
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D016022:Case-Control Studies; D002908:Chronic Disease; D004724:Endoscopy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009298:Nasal Polyps / Q000523:psychology* / Q000601:surgery; D013517:Otorhinolaryngologic Surgical Procedures; D011184:Postoperative Period; D011446:Prospective Studies; D011788:Quality of Life; D012852:Sinusitis / Q000523:psychology* / Q000601:surgery; D016896:Treatment Outcome; D055815:Young Adult