title: Population-based fitting of medial shape models with correspondence optimization.
abstract: A crucial problem in statistical shape analysis is establishing the correspondence of shape features across a population. While many solutions are easy to express using boundary representations, this has been a considerable challenge for medial representations. This paper uses a new 3-D medial model that allows continuous interpolation of the medial manifold and provides a map back and forth between it and the boundary. A measure defined on the medial surface then allows one to write integrals over the boundary and the object interior in medial coordinates, enabling the expression of important object properties in an object-relative coordinate system. We use these integrals to optimize correspondence during model construction, reducing variability due to the model parameterization that could potentially mask true shape change effects. Discrimination and hypothesis testing of populations of shapes are expected to benefit, potentially resulting in improved significance of shape differences between populations even with a smaller sample size.
authors.affiliation: Dept. of Computer Science, Univ. of North Carolina, Chapel Hill, NC 27599, USA. tterribe@cs.unc.edu
authors.forename: Timothy B
authors.initials: TB
authors.lastname: Terriberry
authors.forename: James N
authors.initials: JN
authors.lastname: Damon
authors.forename: Stephen M
authors.initials: SM
authors.lastname: Pizer
authors.forename: Sarang C
authors.initials: SC
authors.lastname: Joshi
authors.forename: Guido
authors.initials: G
authors.lastname: Gerig
mesh_terms: D000465:Algorithms; D002421:Caudate Nucleus / Q000033:anatomy & histology*; D003198:Computer Simulation; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D021621:Imaging, Three-Dimensional / Q000379:methods*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008953:Models, Anatomic; D008959:Models, Neurological