title: Aptamer-based strategies for stem cell research.
abstract: Aptamers have been introduced to analytical applications, target validation, and drug discovery processes and, recently, applied directly as therapeutic agents. Aptamers can be generated by a method called SELEX (Systematic Evolution of Ligands by Exponential Enrichment). This is quite remarkable for such a young technology, which is only created in the early 1990s. This paper reviews recent new applications of aptamers in stem cell research and tissue engineering.
authors.affiliation: Department of Thoracic, University Hospital of Tuebingen, Tuebingen, Germany.
authors.forename: Ke-Tai
authors.initials: KT
authors.lastname: Guo
authors.forename: Richard
authors.initials: R
authors.lastname: Schäfer
authors.forename: Angela
authors.initials: A
authors.lastname: Paul
authors.forename: Gerhard
authors.initials: G
authors.lastname: Ziemer
authors.forename: Hans P
authors.initials: HP
authors.lastname: Wendel
mesh_terms: D000818:Animals; D052157:Aptamers, Nucleotide / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D018929:Cell Culture Techniques; D006801:Humans; D059630:Mesenchymal Stem Cells; D012106:Research; D052156:SELEX Aptamer Technique; D023822:Tissue Engineering / Q000379:methods*
chemical_list: D052157:Aptamers, Nucleotide