title: [Study on the cost of preventing AIDS transmission from mothers to children: an effect analysis].
abstract: OBJECTIVE
  To evaluate the costs of preventing AIDS transmission from mothers to children in a high-incidence area and to investigate relations between costs and effects, as well as to study the economical effects of this approach.
  
  
  METHODS
  According to the number of patients and each strategy on prevention of AIDS transmission, following aspects were calculated as: the cost of preventing each patient with HIV infection, to avoid the cost of one disability adjusted life year (DALY), to evaluate the cost of each patient with either HIV infection or HIV-infected thereafter,and to calculate the HIV-positive rates in mothers at the same levels between costs and effects.
  
  
  RESULTS
  The costs-effects for stopping pregnancy:it was 2264 Yuan for preventing one DALY, the costs of avoiding one case with HIV infection was 46 963 Yuan, but it was 211,000 Yuan from each patient after HIV infection, the ratio between effects and costs was 4.5:1. The costs-effects for comprehensive strategies showed that the cost was 60 853 Yuan for avoiding one case with HIV infection. It was 211,000 Yuan for each patient after HIV infection and the ratio between effects and costs was 3.5:1.
  
  
  CONCLUSIONS
  The cost-effect of preventing HIV transmission from mothers to children was significant on the basis of economical level. It was more effective to evaluate the relation between costs and effects according to economical level in screening and preventing transmission from mothers to children under the situation that the HIV-positive rate in pregnant mothers was more than 0.03%.
authors.affiliation: School of Medicine and Health Management, Tongji Medical College of Huazhong University of Science and Technology, Wuhan 430030, China.
authors.forename: Jin-ling
authors.initials: JL
authors.lastname: Guo
authors.forename: Yu-ming
authors.initials: YM
authors.lastname: Wang
authors.forename: Shu-ying
authors.initials: SY
authors.lastname: Liang
authors.forename: Zhe
authors.initials: Z
authors.lastname: Wang
authors.forename: Xiao-yan
authors.initials: XY
authors.lastname: Hu
authors.forename: Liang
authors.initials: L
authors.lastname: Zhang
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000191:economics* / Q000517:prevention & control / Q000635:transmission*; D002648:Child; D002681:China; D003362:Cost-Benefit Analysis; D006233:Persons with Disabilities; D005260:Female; D017048:Health Care Costs / Q000706:statistics & numerical data*; D006801:Humans; D007231:Infant, Newborn; D018445:Infectious Disease Transmission, Vertical / Q000191:economics* / Q000517:prevention & control; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000191:economics* / Q000517:prevention & control