title: Primary diffuse large B-cell lymphoma of the spleen with coincident serous retinal detachments responsive to corticosteroids.
abstract: Non-Hodgkin's lymphoma is the sixth leading cause of cancer death in the USA. Herein, a patient is presented with primary diffuse large B-cell lymphoma whose initial complaint was blurred vision and who presented with corticosteroid-responsive serous retinal detachments mimicking Vogt-Koynagi-Harada. Extensive clinical examination including imaging and blood testing was negative. Splenectomy led to a diagnosis of splenic lymphoma.
authors.affiliation: Laboratory of Immunology, National Eye Institute, Bethesda, MD, USA. skk100@pol.net
authors.forename: Shree K
authors.initials: SK
authors.lastname: Kurup
authors.forename: Grace
authors.initials: G
authors.lastname: Levy-Clarke
authors.forename: Katherine R
authors.initials: KR
authors.lastname: Calvo
authors.forename: Elaine S
authors.initials: ES
authors.lastname: Jaffe
authors.forename: Robert B
authors.initials: RB
authors.lastname: Nussenblatt
authors.forename: Chi-Chao
authors.initials: CC
authors.lastname: Chan
mesh_terms: D000284:Administration, Oral; D005451:Fluorescein Angiography; D005938:Glucocorticoids / Q000627:therapeutic use*; D006801:Humans; D016393:Lymphoma, B-Cell / Q000150:complications* / Q000175:diagnosis / Q000601:surgery; D016403:Lymphoma, Large B-Cell, Diffuse / Q000150:complications* / Q000175:diagnosis / Q000601:surgery; D008297:Male; D008875:Middle Aged; D011241:Prednisone / Q000627:therapeutic use*; D012163:Retinal Detachment / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D013156:Splenectomy; D013160:Splenic Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000601:surgery; D041623:Tomography, Optical Coherence
chemical_list: D005938:Glucocorticoids; D011241:Prednisone