title: Dietary counseling and probiotic supplementation during pregnancy modify placental phospholipid fatty acids.
abstract: It has previously been shown that maternal nutrition affects the fetal environment, with consequences for the infant's health. From early pregnancy onwards participants here received a combination of dietary counseling and probiotics (Lactobacillus GG and Bifidobacterium lactis Bb12; n = 10), dietary counseling with placebo (n = 12), or placebo alone (n = 8). The major differences in placental fatty acids were attributable to a higher concentration of n-3 polyunsaturated fatty acids in both intervention arms than in controls. Further, dietary counseling with probiotics resulted in higher concentrations of linoleic (18:2n-6) and dihomo-gamma-linolenic acids (20:3n-6) compared with dietary counseling with placebo or controls.
authors.affiliation: Functional Foods Forum, University of Turku, 20014, Turku, Finland.
authors.forename: Niina
authors.initials: N
authors.lastname: Kaplas
authors.forename: Erika
authors.initials: E
authors.lastname: Isolauri
authors.forename: Anna-Maija
authors.initials: AM
authors.lastname: Lampi
authors.forename: Tiina
authors.initials: T
authors.lastname: Ojala
authors.forename: Kirsi
authors.initials: K
authors.lastname: Laitinen
mesh_terms: D003376:Counseling; D004041:Dietary Fats / Q000008:administration & dosage; D005231:Fatty Acids, Unsaturated / Q000032:analysis*; D005260:Female; D006801:Humans; D039382:Maternal Nutritional Physiological Phenomena; D008431:Maternal-Fetal Exchange; D010743:Phospholipids / Q000737:chemistry*; D010920:Placenta / Q000737:chemistry*; D011247:Pregnancy; D019936:Probiotics / Q000008:administration & dosage*
chemical_list: D004041:Dietary Fats; D005231:Fatty Acids, Unsaturated; D010743:Phospholipids