Dyslipidaemia associated with the highly active antiretroviral therapy in AIDS patient: reversion after switching (stavudine to tenofovir and lopinavir/ritonavir to atazanavir/ritonavir).
Antiretroviral therapy has been associated with hyperlipidemia in AIDS patients. This case illustrates the classic metabolic effects associated to the HAART including protease inhibitors and/or stavudine. It was showed that the management of the HAART-associated dyslipidaemia with conventional antihyperlipidemic therapy may fail, being the switching strategy the best option.
Domingos
Hamilton
H
Federal University of Mato Grosso do Sul, 79050-112 Campo Grande, MS, Brazil. hmdomingos@brturbo.com.br
da Cunha
Rivaldo Venâncio
RV
Paniago
Anamaria Mello Miranda
AM
D000328:Adult; D019380:Anti-HIV Agents / Q000008:administration & dosage / Q000009:adverse effects*; D023241:Antiretroviral Therapy, Highly Active / Q000009:adverse effects*; D050171:Dyslipidemias / Q000139:chemically induced* / Q000188:drug therapy; D015658:HIV Infections / Q000097:blood / Q000188:drug therapy*; D017320:HIV Protease Inhibitors / Q000008:administration & dosage / Q000009:adverse effects*; D006801:Humans; D000960:Hypolipidemic Agents / Q000627:therapeutic use; D008055:Lipids / Q000097:blood; D008297:Male
D019380:Anti-HIV Agents; D017320:HIV Protease Inhibitors; D000960:Hypolipidemic Agents; D008055:Lipids