title: [Intraarterial chemotherapy using implantable port-catheter system in patients with colorectal liver metastases].
abstract: We evaluated the tentative clinical results of port-catheter system implantation in 32 patients (18 males and 14 females) with liver metastases of colorectal cancer (2001-2006). Laparotomic approach was used in 17 and percutaneous transfemoral implantation - in 15 patients. There were no complications nor technical problems. All patients received a total of 160 cycles of infusion chemotherapy, ranging 2-11 (4 on the average); mean follow-up - 241 (57-730) days . At present, 21 patients have survived for 5-28 months. Three of them (14%) report complete response, 13 (62%) - stabilization and 5 (24%) - tumor progression. One-year survival in all patients was in 76.5%. Eleven patients died through tumor progression unrelated to the liver.
authors.forename: M I
authors.initials: MI
authors.lastname: Generalov
authors.forename: P V
authors.initials: PV
authors.lastname: Balakhnin
authors.forename: I O
authors.initials: IO
authors.lastname: Rutkin
authors.forename: V N
authors.initials: VN
authors.lastname: Polysalov
authors.forename: P G
authors.initials: PG
authors.lastname: Tarazov
authors.forename: A A
authors.initials: AA
authors.lastname: Polikarpov
authors.forename: E V
authors.initials: EV
authors.lastname: Rozengauz
authors.forename: A A
authors.initials: AA
authors.lastname: Ivanova
authors.forename: P A
authors.initials: PA
authors.lastname: Kalashnikov
authors.forename: D A
authors.initials: DA
authors.lastname: Granov
mesh_terms: D000368:Aged; D002408:Catheters, Indwelling; D010478:Chemotherapy, Cancer, Regional Perfusion / Q000379:methods*; D015179:Colorectal Neoplasms / Q000473:pathology*; D005260:Female; D006801:Humans; D007261:Infusions, Intra-Arterial / Q000379:methods*; D008113:Liver Neoplasms / Q000188:drug therapy* / Q000556:secondary* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D016896:Treatment Outcome