Cutaneous neonatal lupus erythematosus with unusual features.
A three month-old boy was brought by his mother with complaints of multiple reddish lesions on his trunk and face since birth. The patient had erythematous annular plaques with scaling on his extremities, palms and soles with periorbital erythema and edema giving the characteristic "eye mask" or "owl's eye" appearance. His mother did not have history of any illness. Hemogram, liver and renal function tests were within normal limits. A skin biopsy was suggestive of subacute cutaneous lupus erythematosus. Immunological work-up was positive for antinuclear antibodies (ANA) (1:40) with anti-Ro titers of 3.4 and 3.47 (>1.1 = clinically significant titre) in the mother and child respectively, although negative for anti-La antibodies. The child's electrocardiogram and 2D echocardiography were normal. We are presenting a case of anti-Ro-positive cutaneous lupus erythematosus with an uncommon skin manifestation.
Department of Dermatology, T. N. Medical College and BYL Nair Charitable Hospital, Mumbai, India. mangeshnikam@yahoo.com
Shankar
S
Sawant
S T
ST
Amladi
S L
SL
Wadhawa
C S
CS
Nayak
B P
BP
Nikam
D001323:Autoantibodies / Q000097:blood; D005145:Face / Q000473:pathology; D006801:Humans; D007223:Infant; D008178:Lupus Erythematosus, Cutaneous / Q000097:blood / Q000151:congenital* / Q000473:pathology; D008297:Male; D012867:Skin / Q000473:pathology
D001323:Autoantibodies