[Isolation frequency and spectrum of sensitivity to antifungal preparations of vulvovaginal candidiasis pathogens].
The conducted microbiological examination of 362 women of reproductive age has shown the availability of vulvovaginal candidiasis in 282 of them. The following representatives of the genus Candida were isolated from the urogenital tract of women: C. albicans (53%), C. krusei (18%), C. glabrata (14%), C. tropicalis (9%), C. pseudotropicalis (6%). The comparative analysis of sensitivity of the given fungi to a number of antimycotic preparations used in the clinic has been conducted. One can observe maximum sensitivity (89%) of the isolated fungi of Candida genus to itraconazole, minimum (49%)--to nystatin. Therefore itraconazole can be a preparation of choice when treating vulvovaginal candidiasis, which agents are the Candida genus fungi being resistant to other antimycotics.
T V
TV
Skliar
A V
AV
Krysenko
E A
EA
Sirokvasha
A I
AI
Vinnikov
D000328:Adult; D000935:Antifungal Agents / Q000494:pharmacology*; D002175:Candida / Q000145:classification / Q000187:drug effects* / Q000302:isolation & purification; D002181:Candidiasis, Vulvovaginal / Q000453:epidemiology* / Q000382:microbiology*; D005260:Female; D006801:Humans; D008826:Microbial Sensitivity Tests
D000935:Antifungal Agents