[Acylhydrazones of 20-keto steroids and their transformations: I. Synthesis and properties of 1'-acyl-substituted 3'-methylandrosteno[16,17-d]pyrazolines].
Acetates of 3beta-hydroxy-3'-methyl-1'(N)-acylandrost-5-eno[16,17-d]pyrazolines bearing monothiooxamide acyl groups were synthesized during the study of approaches to the synthesis of 3'-methylandrosteno[16,17-d]azoles, promising biologically active analogues of 20-keto pregnenanes, and their properties were investigated. The cyclization of delta16-20-thiooxamidohydrazones to the corresponding heterocycles was shown to proceed under rigorous conditions and to depend partially on the nature of the oxamide grouping.
Kamernitskiĭ
A V
AV
Chernoburova
E I
EI
Chertkova
V V
VV
Zavarzin
I V
IV
Iarovenko
V N
VN
Kraiushkin
M M
MM
D000736:Androstenes / Q000138:chemical synthesis* / Q000737:chemistry; D006835:Hydrazones / Q000138:chemical synthesis / Q000737:chemistry; D011284:Pregnenolone / Q000031:analogs & derivatives / Q000737:chemistry; D011720:Pyrazoles / Q000138:chemical synthesis* / Q000737:chemistry
D000736:Androstenes; D006835:Hydrazones; D011720:Pyrazoles; D011284:Pregnenolone; C007240:dehydropregnenolone acetate