Nitrosoureas: molecular pharmacology/ translational research.
D'Incalci
Maurizio
M
Dipartimento di Oncologia, Istituto di Ricerche Farmacologiche Mario Negri, Milano.
D018906:Antineoplastic Agents, Alkylating / Q000737:chemistry / Q000493:pharmacokinetics / Q000494:pharmacology / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D003432:Cross-Linking Reagents / Q000737:chemistry / Q000493:pharmacokinetics / Q000494:pharmacology / Q000627:therapeutic use; D004249:DNA Damage; D015254:DNA Modification Methylases / Q000037:antagonists & inhibitors / Q000378:metabolism; D045643:DNA Repair Enzymes / Q000037:antagonists & inhibitors / Q000378:metabolism; D004273:DNA, Neoplasm / Q000187:drug effects; D015195:Drug Design; D019008:Drug Resistance, Neoplasm; D006801:Humans; D008745:Methylation; D015394:Molecular Structure; D009363:Neoplasm Proteins / Q000037:antagonists & inhibitors / Q000378:metabolism; D009369:Neoplasms / Q000188:drug therapy* / Q000235:genetics; D009607:Nitrosourea Compounds / Q000737:chemistry / Q000493:pharmacokinetics / Q000494:pharmacology / Q000627:therapeutic use*; D025521:Tumor Suppressor Proteins / Q000037:antagonists & inhibitors / Q000378:metabolism
D018906:Antineoplastic Agents, Alkylating; D003432:Cross-Linking Reagents; D004273:DNA, Neoplasm; D009363:Neoplasm Proteins; D009607:Nitrosourea Compounds; D025521:Tumor Suppressor Proteins; D015254:DNA Modification Methylases; C515491:MGMT protein, human; D045643:DNA Repair Enzymes