Human granulocytic anaplasmosis during pregnancy: case series and literature review.
We describe the clinical and laboratory manifestations and pregnancy outcomes of 6 women who received a diagnosis of human granulocytic ehrlichiosis during pregnancy. Human granulocytic ehrlichiosis did not seem to present in a fulminant fashion, and all treated patients had excellent responses to rifampin or doxycycline therapy. Perinatal transmission was documented in 1 neonate, who responded well to treatment. There do not appear to be any long-term adverse sequelae in children born from these pregnancies (mean follow-up duration, 21 months).
Department of Medicine, Division of Infectious Diseases, New York Medical College, Valhalla, NY, USA.
Abhay
A
Dhand
Robert B
RB
Nadelman
Maria
M
Aguero-Rosenfeld
Fadi A
FA
Haddad
Daniela P
DP
Stokes
Harold W
HW
Horowitz
D000328:Adult; D041081:Anaplasma phagocytophilum / Q000187:drug effects / Q000472:pathogenicity; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D004318:Doxycycline / Q000627:therapeutic use*; D016873:Ehrlichiosis / Q000150:complications* / Q000188:drug therapy / Q000635:transmission; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007231:Infant, Newborn; D018445:Infectious Disease Transmission, Vertical; D009518:New York; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000188:drug therapy*; D011256:Pregnancy Outcome; D012293:Rifampin / Q000627:therapeutic use*
D000900:Anti-Bacterial Agents; D004318:Doxycycline; D012293:Rifampin