Past, present and future of mass spectrometry in the analysis of residues of banned substances in meat-producing animals.
A residue is a trace (microg kg(-1), ng kg(-1)) of a substance, present in a matrix. Banned substances, such as growth promoters, which are abused in animal fattening and where this article is focused on, may be divided into four major groups: thyreostats, anabolics or anabolic steroids, corticosteroids and beta-agonists or repartitioning agents. The combination of chromatographic techniques with mass spectrometry (GC-MS(n), LC-MS(n), etc.) plays a key role in the production of specific results in residue analysis. In this review, the past, present and future of mass spectrometry in this area are discussed in the light of the impact of these substances on human health and the reliable production of analytical results, ready for challenge in a court.
De Brabander
H F
HF
Ghent University, Faculty of Veterinary Medicine, Department of Veterinary Public Health and Food Safety, Lab Chemical Analysis, Salisburylaan 133, B-9820 Merelbeke, Belgium. Hubert.DeBrabander@UGent.be
Le Bizec
B
B
Pinel
G
G
Antignac
J-P
JP
Verheyden
K
K
Mortier
V
V
Courtheyn
D
D
Noppe
H
H
D000818:Animals; D000829:Animals, Domestic; D004350:Drug Residues / Q000032:analysis*; D004784:Environmental Monitoring / Q000331:legislation & jurisprudence / Q000379:methods*; D005506:Food Contamination / Q000331:legislation & jurisprudence / Q000517:prevention & control*; D006133:Growth Substances / Q000032:analysis*; D006801:Humans; D013058:Mass Spectrometry / Q000379:methods* / Q000639:trends; D008460:Meat
D006133:Growth Substances