3alpha,4alpha-Epoxy-2-piperidone, a new minor derivative from leaves of Piper crassinervium Kunth (Piperaceae).
A new antifungal piperidone derivative 3alpha,4alpha-epoxy-2-piperidone, whose structure was determined by spectroscopic methods, was isolated from the MeOH extract from leaves of Piper crassinervium. This is the first occurrence of one amide in P. crassinervium.
Centro de Ciências e Humanidades, Universidade Presbiteriana Mackenzie, São Paulo, SP, Brazil. joaolago@iq.usp.br
João Henrique G
JH
Lago
Massuo J
MJ
Kato
D000935:Antifungal Agents / Q000008:administration & dosage / Q000737:chemistry / Q000494:pharmacology* / Q000627:therapeutic use; D002963:Cladosporium / Q000187:drug effects*; D006801:Humans; D008826:Microbial Sensitivity Tests; D008517:Phytotherapy; D031701:Piper; D010881:Piperidones / Q000008:administration & dosage / Q000737:chemistry / Q000494:pharmacology / Q000627:therapeutic use; D010936:Plant Extracts / Q000008:administration & dosage / Q000737:chemistry / Q000494:pharmacology* / Q000627:therapeutic use; D018515:Plant Leaves
D000935:Antifungal Agents; D010881:Piperidones; D010936:Plant Extracts