14-3-3 proteins in plant brassinosteroid signaling.
Brassinosteroid (BR) signaling requires the BIN2 kinase-promoted interaction of 14-3-3 proteins with the transcriptional regulators BZR1 and BZR2, which are subsequently redistributed to the cytoplasm by BRs. In this issue of Developmental Cell, Gampala et al. show that this redistribution may fine-tune BR responses and serve to crosstalk with other signaling pathways.
Laboratory of Biochemistry, Department of Food Sciences and Nutrition, Wageningen University, Dreijenlaan 3, 6703 HA Wageningen, The Netherlands. sacco.devries@wur.nl
Sacco C
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de Vries
D048948:14-3-3 Proteins / Q000737:chemistry / Q000378:metabolism*; D017360:Arabidopsis / Q000187:drug effects / Q000378:metabolism*; D029681:Arabidopsis Proteins / Q000737:chemistry / Q000235:genetics / Q000378:metabolism; D004268:DNA-Binding Proteins; D019281:Dimerization; D006801:Humans; D008954:Models, Biological; D009687:Nuclear Proteins / Q000737:chemistry / Q000235:genetics / Q000378:metabolism; D011494:Protein Kinases / Q000378:metabolism; D015398:Signal Transduction; D013260:Steroids, Heterocyclic / Q000378:metabolism* / Q000494:pharmacology
D048948:14-3-3 Proteins; D029681:Arabidopsis Proteins; D004268:DNA-Binding Proteins; D009687:Nuclear Proteins; D011494:Protein Kinases; D013260:Steroids, Heterocyclic; C456160:BES1 protein, Arabidopsis; C454444:BZR1 protein, Arabidopsis; C448985:At4g18710 protein, Arabidopsis