N-heterocyclic carbene catalyzed ring expansion of 4-formyl-beta-lactams: synthesis of succinimide derivatives.
N-heterocyclic carbene (NHC) has been employed as an efficient catalyst for ring expansion of 4-formyl-beta-lactams, allowing the facile synthesis of succinimide derivatives. This organocatalytic process features readily availability of the catalyst, low catalyst loading, and mild reaction conditions.
Li
Gong-Qiang
GQ
State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 354 Fenglin Lu, Shanghai 200032, China.
Li
Yi
Y
Dai
Li-Xin
LX
You
Shu-Li
SL