The relationship between anterior chamber depth and the presence of diabetes in the Tanjong Pagar Survey.
OBJECTIVE
To examine the relationships of diabetes with anterior chamber depth, axial length, and refraction.


METHODS
Population-based cross-sectional study.


METHODS
This analysis included 943 Singapore Chinese subjects ages 40 to 81 years from the Tanjong Pagar Survey. Diabetes was determined by self-report. A-mode ultrasound was used to measure axial dimensions. Refraction was performed with an autorefractor and refined subjectively.


RESULTS
There were 140 (11.4%) participants with diabetes. After controlling for age and gender, participants with diabetes had shallower anterior chambers (2.78 vs 2.91 mm, P = .004) and thicker lenses (4.88 vs 4.75 mm, P = .003), but similar spherical equivalent refraction (-0.38 vs -0.47 diopters [D], P = .73), axial length (23.09 vs 23.19 mm, P = .40), and vitreous chamber depth (15.52 vs 15.59 mm, P = .53).


CONCLUSIONS
In the Singapore Chinese population, persons with diabetes have shallower anterior chambers and thicker lenses than those without diabetes. Diabetes may be a risk factor for angle closure glaucoma (ACG).
Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore. cofsawsm@nus.edu.sg
Seang-Mei
SM
Saw
Tien Y
TY
Wong
Steven
S
Ting
Athena W P
AW
Foong
Paul J
PJ
Foster
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000867:Anterior Chamber / Q000000981:diagnostic imaging*; D044466:Asian People; D003430:Cross-Sectional Studies; D003920:Diabetes Mellitus / Q000175:diagnosis* / Q000208:ethnology*; D006801:Humans; D008875:Middle Aged; D011159:Population Surveillance; D015995:Prevalence; D012189:Retrospective Studies; D012307:Risk Factors; D012846:Singapore / Q000453:epidemiology; D014463:Ultrasonography