ICMRBS founder's medal 2006: biological solid-state NMR, methods and applications.
Solid-state NMR (ssNMR) provides increasing possibilities to study structure and dynamics of biomolecular systems. Our group has been interested in developing ssNMR-based approaches that are applicable to biomolecules of increasing molecular size and complexity without the need of specific isotope-labelling. Methodological aspects ranging from spectral assignments to the indirect detection of proton-proton contacts in multi-dimensional ssNMR are discussed and applied to (membrane) protein complexes.
Baldus
Marc
M
Research Group Solid-state NMR, Max Planck Institute for Biophysical Chemistry, Am Fassberg 11, 37077 Gottingen, Germany. maba@mpibpc.mpg.de
D000595:Amino Acid Sequence; D000682:Amyloid / Q000737:chemistry; D001363:Awards and Prizes; D008024:Ligands; D008280:Magnetics; D008565:Membrane Proteins / Q000737:chemistry; D008969:Molecular Sequence Data; D019906:Nuclear Magnetic Resonance, Biomolecular / Q000379:methods*; D017510:Protein Folding; D017433:Protein Structure, Secondary; D011522:Protons
D000682:Amyloid; D008024:Ligands; D008565:Membrane Proteins; D011522:Protons