Experience of famine and bone health in post-menopausal women.
BACKGROUND
Famines have occurred in all areas of the world in every period of history. Many studies have shown that poor growth and development and adverse environmental conditions in childhood are associated with osteoporosis in later life. However, little information is available on the relation between famine and bone health.


METHODS
This study examines the hypothesis that past experience of famine has an adverse impact on bone health, using data from Ms Os (Hong Kong), a large cohort study on osteoporosis in Asian women. There were 1,826 Hong Kong women aged 65 years or older recruited from the community. A standardized, structured interview and DXA were performed. Subjects who had experienced famine tended to have lower levels of education, social status and current daily calcium intake. They also have higher rates of cigarette consumption, depression and coronary heart disease.


RESULTS
After adjustment for confounders, we found that subjects who had experienced famine have a significantly higher rate of developing osteoporosis than those who had not.


CONCLUSIONS
We conclude that past exposure to famine, especially in childhood, is associated with osteoporosis.
Department of Community and Family Medicine, School of Public Health, The Chinese University of Hong Kong, Hong Kong SAR. cwkfrank@cuhk.edu.hk
Chan Frank Wan
CF
Kin
Wong Samuel Yeung
WS
Shan
Leung Jason Chi
LJ
Shun
Leung Ping
LP
Chung
Woo
W
Jean
D015502:Absorptiometry, Photon; D000368:Aged; D000886:Anthropometry / Q000379:methods; D015519:Bone Density; D004522:Educational Status; D005260:Female; D006723:Hong Kong / Q000453:epidemiology; D006801:Humans; D008019:Life Style; D015663:Osteoporosis, Postmenopausal / Q000453:epidemiology* / Q000209:etiology* / Q000503:physiopathology; D012307:Risk Factors; D012923:Social Class; D013217:Starvation / Q000150:complications* / Q000503:physiopathology