[Influence of perioperative administration of amino acids on thermoregulation response in patients underwent colorectal surgical procedures].
BACKGROUND
Hypothermia in the surgical patients can be the consequence of long duration of surgical intervention, general anesthesia and low temperature in operating room. Postoperative hypothermia contributes to a number of postoperative complications such as arrythmia, myocardial ischemia, hypertension, bleeding, wound infection, coagulopathy, prolonged effect of muscle relaxants. External heating procedures are used to prevent this condition, but some investigations reported that infusion of aminoacids during surgery can induce thermogenesis and prevent postoperative hypothermia.


METHODS
We reported two males who underwent major colorectal surgery for rectal carcinoma. One patient recived Aminosol 15% solution, 125 ml/h, while the other did not. The esophageal temperatures in both cases were measured every 30 minutes during the operation and 60 minutes after in Intensive Care Unit. We were monitoring blood pressure, heart rate, ECG, and shivering. Patient who received aminoacids showed ameliorated postoperative hypothermia without hypertension, arrythmia, or shivering, while the other showed all symptoms mentioned above.


CONCLUSIONS
According to literature data, as well as our findings, we can conclude that intraoperative intravenous treatment with amino acid solution ameliorates postoperative hypothermia along with its complications.
Zeba
Snjezana
S
Vojnomedicinska akademija, Klinika za anesteziologiju i intenzivnu negu, Beograd, Srbija.
Surbatović
Maja
M
Jevtić
Miodrag
M
Filipović
Nikola
N
Popović
Nada
N
Radaković
Sonja
S
Slavković
Zoran
Z
D000368:Aged; D001831:Body Temperature; D001833:Body Temperature Regulation; D006801:Humans; D007035:Hypothermia / Q000517:prevention & control*; D007262:Infusions, Intravenous; D007432:Intraoperative Period; D008297:Male; D011183:Postoperative Complications / Q000517:prevention & control*; D011492:Protein Hydrolysates / Q000008:administration & dosage*; D012007:Rectum / Q000601:surgery*
D011492:Protein Hydrolysates; C010025:aminosol