Stereoselective synthesis of (E)- and (Z)-enol ethers from beta-amino aldehydes.
Stereocontrolled methods for the direct and divergent synthesis of the silylenol ethers possessing amino group from beta-amino aldehydes have been achieved. These enol ethers with the defined olefin geometry could be key building blocks for the synthesis of the medicinally impor tant compounds.
In
Jin-Kyung
JK
College of Pharmacy, Chungbuk National University, Cheongju 361-763, Korea.
Lee
Mi-Sung
MS
Lee
Min-Woo
MW
Kwak
Jae-Hwan
JH
Lee
Heesoon
H
Hong
Jin Tae
JT
Chung
Yongseog
Y
Choi
Yongseok
Y
Jung
Jae-Kyung
JK
D000447:Aldehydes / Q000737:chemistry*; D000475:Alkenes / Q000737:chemistry; D000478:Alkylation; D001593:Benzyl Compounds / Q000138:chemical synthesis; D004987:Ethers / Q000138:chemical synthesis*; D007202:Indicators and Reagents; D009682:Magnetic Resonance Spectroscopy; D008745:Methylation; D012821:Silanes / Q000138:chemical synthesis; D013237:Stereoisomerism
D000447:Aldehydes; D000475:Alkenes; D001593:Benzyl Compounds; D004987:Ethers; D007202:Indicators and Reagents; D012821:Silanes