Cystic sebaceous carcinoma: is it a constant pathognomic marker for Muir-Torre syndrome?
Sebaceous carcinoma (SC) is a rare and aggressive cutaneous neoplasm. It may arise in ocular or extraocular sites. Approximately 25% of all reported cases of SC are extraocular. Cystic presentation of sebaceous neoplasm is rare. So far, cystic sebaceous neoplasia (CSN) has been reported only in association with Muir-Torre syndrome (MTS). Furthermore, CSN has recently been characterized as a marker lesion of MTS. We report a case of CSN of the nose that was not associated with MTS. Mohs micrographic surgery was performed with no recurrence for 2 years. Patients with MTS need long-term follow-up to detect possible future presentation of MTS.
Dermatology Department, College of Medicine and King Khalid University Hospital, King Saud University, Riyadh, Kingdom of Saudi Arabia. hanisat@yahoo.com
Hani A
HA
Al-Shobaili
Khalid M
KM
AlGhamdi
Walid A
WA
Al-Ghamdi
D018266:Adenocarcinoma, Sebaceous / Q000209:etiology / Q000473:pathology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D015580:Mohs Surgery; D018297:Neoplasms, Cystic, Mucinous, and Serous / Q000209:etiology / Q000473:pathology*; D012878:Skin Neoplasms / Q000209:etiology / Q000473:pathology*; D013577:Syndrome