Fatal pulmonary Mycobacterium xenopi in a patient with rheumatoid arthritis receiving etanercept.
Mycobacterium xenopi is a water-related mycobacterium with low pathogenicity in humans. Little is known about the association between anti-tumour necrosis factor (TNF)alpha and non-tuberculous mycobacterial infections. The case history is presented of fatal M xenopi infection in a patient receiving anti-TNFalpha treatment.
Division of Respirology, University Health Network and Mount Sinai Hospital, Department of Medicine, University of Toronto, Toronto, Canada.
Nimrod
N
Maimon
James
J
Brunton
Adrienne K
AK
Chan
Theodore K
TK
Marras
D000368:Aged; D018501:Antirheumatic Agents / Q000009:adverse effects*; D001172:Arthritis, Rheumatoid / Q000188:drug therapy; D000068800:Etanercept; D017809:Fatal Outcome; D006801:Humans; D007074:Immunoglobulin G / Q000009:adverse effects*; D007166:Immunosuppressive Agents / Q000009:adverse effects*; D008297:Male; D009165:Mycobacterium Infections, Nontuberculous / Q000139:chemically induced*; D019912:Mycobacterium xenopi; D009894:Opportunistic Infections / Q000139:chemically induced*; D018124:Receptors, Tumor Necrosis Factor; D014397:Tuberculosis, Pulmonary / Q000139:chemically induced*
D018501:Antirheumatic Agents; D007074:Immunoglobulin G; D007166:Immunosuppressive Agents; D018124:Receptors, Tumor Necrosis Factor; D000068800:Etanercept