Longitudinal myelitis in patient with systemic lupus erythematosus, homozygous prothrombin G20210A and heterozygous MTHFR 677T.
Longitudinal myelitis is an uncommon complication of systemic lupus erythematosus (SLE). We describe an unusual case of longitudinal myelitis and ischemic stroke in the presence of homozygous prothrombin G20210A, heterozygous MTHFR 677T mutations and the absence of antiphospholipid antibodies in a young woman with SLE.
Department of Internal Medicine, Division of Rheumatology, American University of Beirut Medical Center, New York, NY 10017-2303, USA.
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Touma
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Atweh
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Kibbi
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Arayssi
D000328:Adult; D004247:DNA / Q000235:genetics*; D005260:Female; D005500:Follow-Up Studies; D006579:Heterozygote; D006720:Homozygote; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications* / Q000175:diagnosis / Q000235:genetics; D008279:Magnetic Resonance Imaging; D009154:Mutation; D009187:Myelitis / Q000150:complications* / Q000175:diagnosis / Q000235:genetics; D011516:Prothrombin / Q000235:genetics*; D012720:Severity of Illness Index; D013997:Time Factors
D011516:Prothrombin; D004247:DNA