Monitoring lung fluid content in CHF patients under intravenous diuretics treatment using bio-impedance measurements.
A pulmonary edema monitoring system (PulmoTrace, CardioInspect, Tel-Aviv University, Israel) was evaluated for tracking lung resistivity during diuretics treatment in congestive heart failure (CHF) patients. The system incorporates a bio-impedance measurement algorithm and enables, by employing an eight-electrode thoracic belt, the assessment of both the left- and right-lung resistivity values. A clinical study was conducted on a group of 13 CHF patients under intravenous diuretics treatment. The group was measured twice-before the beginning of treatment and following a period of a couple of hours. An increase of 8% of the mean lung resistivity (median value) was found between the two measuring sessions, which indicates a dehydration of the lungs, and a significant correlation (R=0.73, p=0.004) was found between the lung resistivity change and the urine output. In conjunction with previously reported results, which demonstrated the system's reproducibility and long-term monitoring capabilities, this study further supports the diagnostics value of the system.
Freimark
D
D
Department of Cardiology, Sheba Medical Center, Ramat-Gan, Israel.
Arad
M
M
Sokolover
R
R
Zlochiver
S
S
Abboud
S
S
D000368:Aged; D000465:Algorithms; D004232:Diuretics / Q000008:administration & dosage*; D016903:Drug Monitoring / Q000295:instrumentation / Q000379:methods; D017097:Electric Impedance; D004566:Electrodes; D015633:Extravascular Lung Water / Q000378:metabolism*; D006333:Heart Failure / Q000150:complications* / Q000378:metabolism; D006801:Humans; D007275:Injections, Intravenous; D008297:Male; D008875:Middle Aged; D008991:Monitoring, Physiologic / Q000295:instrumentation / Q000379:methods; D011654:Pulmonary Edema / Q000175:diagnosis* / Q000188:drug therapy* / Q000378:metabolism
D004232:Diuretics