[Prevalence and in vitro antimicrobial susceptibility patterns of Acinetobacter baumannii strains in a Moroccan university hospital].
OBJECTIVE
The aim of this study was to identify the clinical presentations and the current antimicrobial susceptibility of Acinetobacter baumannii.


RESULTS
We identified 754 strains especially from intensive care units (50.53%) between January 2003 and December 2005. Bronchial swabs and blood culture were prevalent. High-level resistance to betalactamines was noted: 91% to cefotaxime, 50.3% to ceftazidime, and 42.6% to imipenem. Aminoside resistance varied from 17.9% for netilmicine to 72.1% for gentamycin. The resistance rate to ciprofloxacine was 65.8%, and to trimethoprime-sulfamethoxazole 75.8%. In intensive care units, the antimicrobial resistance rate of A. baumannii was higher (p<0.05).


CONCLUSIONS
The resistance of A. baumannii to current antibiotics is alarming especially in intensive care units. An effective strategy against nosocomial infection is still necessary.
Lahsoune
M
M
Laboratoire de microbiologie, faculté de médecine et de pharmacie, 19, rue Tarik-Bnou-Zyad, Casablanca, Maroc.
Boutayeb
H
H
Zerouali
K
K
Belabbes
H
H
El Mdaghri
N
N
D040981:Acinetobacter baumannii / Q000187:drug effects*; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D024881:Drug Resistance, Bacterial; D006785:Hospitals, University; D006801:Humans; D007362:Intensive Care Units; D008826:Microbial Sensitivity Tests; D009018:Morocco; D009894:Opportunistic Infections / Q000188:drug therapy / Q000382:microbiology*
D000900:Anti-Bacterial Agents