Novel methods for preparing phospholipid coated microbubbles.
Two new methods for preparing phospholipid coated microbubble suspensions are elucidated. Firstly, co-axial electrohydrodynamic atomisation was utilized to generate 3-7 microm diameter microbubbles. Secondly, a specially designed and constructed T-junction device was used to prepare monodisperse microbubbles. Characteristics of microbubbles prepared by these two methods are compared with those obtained by sonication of the phospholipid suspension.
Pancholi
K P
KP
Department of Mechanical Engineering, University College London, Torrington Place, London, UK.
Farook
U
U
Moaleji
R
R
Stride
E
E
Edirisinghe
M J
MJ
D001703:Biophysics / Q000379:methods*; D003287:Contrast Media; D004563:Electrochemistry / Q000379:methods; D004867:Equipment Design; D045423:Microbubbles; D055095:Optics and Photonics; D010316:Particle Size; D010743:Phospholipids / Q000737:chemistry*; D013010:Sonication; D014465:Ultrasonics
D003287:Contrast Media; D010743:Phospholipids