Highly regioselective synthesis of indene derivatives including an allene functional group via Pd/C-catalyzed cyclization reaction in air.
Indene derivatives including an allene functional group are readily prepared in moderate to excellent yields with high regioselectivity under very mild reaction conditions by the Pd/C-catalyzed reaction of propargylic compounds. The resulting products can be further elaborated using Pd-catalyzed annulation reactions.
Bi
Hai-Peng
HP
State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, People's Republic of China.
Liu
Xue-Yuan
XY
Gou
Fa-Rong
FR
Guo
Li-Na
LN
Duan
Xin-Hua
XH
Liang
Yong-Min
YM