Retropharyngeal neuroblastoma in a neonate: case report and literature review.
Primary cervical neuroblastoma (NB) in neonates is extremely rare. We treated a 1-day-old male neonate who presented with stridor and feeding difficulty and was subsequently diagnosed with NB of the retropharynx. The tumor was excised in toto transorally, and no metastatic lesions were confirmed. Histopathology and molecular genetic analysis showed poorly differentiated NB with no N-myc amplification, stage I NB. He has had no signs of recurrence or adverse sequelae during 18 months of follow-up. We report our experience and review the literature.
Okazaki
Tadaharu
T
Department of Pediatric General and Urogenital Surgery, Juntendo University School of Medicine, 2-1-1 Hongo, Bunkyo-ku, Tokyo, 113-8421, Japan. okazakit@med.juntendo.ac.jp
Ohshita
Masaaki
M
Furukawa
Masayuki
M
Ikeda
Katsuhisa
K
Ozaki
Yutaka
Y
Lane
Geoffrey J
GJ
Yamataka
Atsuyuki
A
D003131:Combined Modality Therapy; D016259:Genes, myc / Q000235:genetics; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D009447:Neuroblastoma / Q000175:diagnosis* / Q000235:genetics / Q000473:pathology / Q000628:therapy; D010610:Pharyngeal Neoplasms / Q000175:diagnosis* / Q000235:genetics / Q000473:pathology / Q000628:therapy