Unraveling the ceramide-calpain-caspase connection in cadmium-induced apoptosis: a novel role for ceramides as activators of calpains. Focus on "Cadmium-induced ceramide formation triggers calpain-dependent apoptosis in cultured kidney proximal tubule cells".
Giuliano
G
Ciarimboli
D000818:Animals; D017209:Apoptosis / Q000187:drug effects / Q000502:physiology; D002104:Cadmium / Q000633:toxicity*; D002154:Calpain / Q000378:metabolism*; D020169:Caspases / Q000378:metabolism*; D002461:Cell Line, Transformed; D002518:Ceramides / Q000378:metabolism*; D007687:Kidney Tubules, Proximal / Q000166:cytology*
D002518:Ceramides; D002104:Cadmium; D002154:Calpain; D020169:Caspases