Liver cystic echinococcosis: which cysts are correlated with false negative indirect passive hemagglutination (IHA)?
BACKGROUND
It's generally agreed that calcified liver cystic Echinococcosis (CE) is associated with negative serology; the influence of other cystic features on serologic result remains unclear. The aim of this study is to determine predictive factors of negative indirect passive hemagglutination (IHA) in liver CE.


METHODS
119 patients operated on for liver CE, had preoperative IHA. Correlation was studied between serological result and sex, age of patient and number (single vs multiple), size, ultrasonic type (unilocular, multivesicular, degenerative) and intrabiliary rupture of cyst.


RESULTS
IHA sensitivity was 74.8%. Univaried analysis showed that false negative serology was correlated with age <10 or >20 years (p < 0.01), single cyst (p < 0.006), cystic size <9 cm (p < 0.03) and unilocular or degenerative cyst in comparison with multivesicular type (p < 0.01 and p < 0.03 respectively).


CONCLUSIONS
in liver CE, cystic predictive factors of false negative IHA are single cyst, unilocular or degenerative type and size inferior to 9 cm.
Surgical Department, H. Bourguiba Hospital, Sfax University.
Rafik
R
Mzali
Mohamed
M
Ben Amar
Wassim
W
Kallel
Kamel
K
Kolsi
Mohamed I
MI
Beyrouti
Ali
A
Ayadi
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D002675:Child, Preschool; D004444:Echinococcosis, Hepatic / Q000145:classification / Q000000981:diagnostic imaging / Q000276:immunology*; D005188:False Negative Reactions; D005260:Female; D005544:Forecasting; D006386:Hemagglutination Tests / Q000379:methods / Q000706:statistics & numerical data; D006801:Humans; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D012422:Rupture, Spontaneous; D012680:Sensitivity and Specificity; D012737:Sex Factors; D014463:Ultrasonography