[Analysis of environmental factors and polycystic ovary syndrome].
OBJECTIVE
To investigate environmental risk factors associated with polycystic ovary syndrome (PCOS).


METHODS
A retrospective study was carried out from Feb 2005 to Apr 2006. A total of 108 cases with PCOS and 108 patients without PCOS (control group) were interviewed using a designed questionnaire.


RESULTS
Univariate analysis of environmental factors indicated that risk factors related to PCOS were: occupation, education, disposable plastic cup for drinking, cooking oil fume and indoor decoration, all of which were significantly related to PCOS (P < 0.05). Multi-variate analysis confirmed that the risk factors associated with PCOS were disposable plastic cup for drinking, cooking oil fume and indoor decoration (P value: 0.011, 0.012, 0.026, 0.011, OR value: 2.800, 3.027, 2.370, 2.478).


CONCLUSIONS
PCOS is related to environmental endocrine-disrupting chemicals.
Department of Obstetrics and Gynecology, Second Affiliated Hospital of Nanjing Medical University, Nanjing 210011, China.
Wei-Juan
WJ
Huang
Jia-Yin
JY
Liu
Li-Na
LN
Li
D002681:China / Q000453:epidemiology; D052244:Endocrine Disruptors / Q000506:poisoning*; D004781:Environmental Exposure / Q000009:adverse effects / Q000032:analysis; D005260:Female; D015386:Hazardous Substances / Q000506:poisoning*; D006801:Humans; D010636:Phenols / Q000506:poisoning; D011085:Polycystic Ovary Syndrome / Q000453:epidemiology / Q000209:etiology*; D012189:Retrospective Studies; D012307:Risk Factors; D012907:Smoking / Q000009:adverse effects; D011795:Surveys and Questionnaires
D052244:Endocrine Disruptors; D015386:Hazardous Substances; D010636:Phenols