Intravascular lymphoma in a patient with systemic lupus erythematosus: a case report.
Intravascular lymphoma IVL is a rare and aggressive disorder characterized by proliferation of large lymphoid cells (most commonly B-cells) within the lumen of small vessels of nearly every organ. Obliteration of vessels leads to the different clinical signs, being cutaneous lesions and neurological signs the most frequent presentations, whereas lymph node and reticuloendothelial system involvement is typically absent. No association with SLE has been described up to the present. We report a case of IVL in a patient with systemic lupus erythematosus (SLE) involving skin, central nervous system (CNS) and bone marrow.
Sánchez-Cano
D
D
Unidad de Enfermedades Autoinmunes Sistémicas, Hospital Clínico San Cecilio, Granada, Spain. danisanchezcano@supercable.es
Callejas-Rubio
J L
JL
Vilanova-Mateu
A
A
Gómez-Morales
M
M
Ortego-Centeno
N
N
D001706:Biopsy; D001854:Bone Marrow Cells / Q000473:pathology; D003937:Diagnosis, Differential; D004452:Echocardiography; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications* / Q000175:diagnosis; D016393:Lymphoma, B-Cell / Q000150:complications* / Q000175:diagnosis; D008875:Middle Aged; D014057:Tomography, X-Ray Computed; D019043:Vascular Neoplasms / Q000150:complications* / Q000175:diagnosis