Papillon-Lefevre syndrome in two brothers.
Papillon-Lefevre syndrome is a disorder of keratinization transmitted probably in an autosomal recessive fashion. Two brothers aged 7 and 4 1/2 years, of this syndrome is reported. Both had palmo-plantar keratoderma, early loss of teeth along with involvement of knees and elbows. There was no history of consanguinity between parents.
Rathi
Sanjay K
SK
Dr. Rathi's Skin Clinic, 143, Hill Cart Road, Siliguri-734 401, (WB), India.