The minimum information required for reporting a molecular interaction experiment (MIMIx).
A wealth of molecular interaction data is available in the literature, ranging from large-scale datasets to a single interaction confirmed by several different techniques. These data are all too often reported either as free text or in tables of variable format, and are often missing key pieces of information essential for a full understanding of the experiment. Here we propose MIMIx, the minimum information required for reporting a molecular interaction experiment. Adherence to these reporting guidelines will result in publications of increased clarity and usefulness to the scientific community and will support the rapid, systematic capture of molecular interaction data in public databases, thereby improving access to valuable interaction data.
European Molecular Biology Laboratory (EMBL) - European Bioinformatics Institute, Wellcome Trust Genome Campus, Cambridge, UK. orchard@ebi.ac.uk
Sandra
S
Orchard
Lukasz
L
Salwinski
Samuel
S
Kerrien
Luisa
L
Montecchi-Palazzi
Matthias
M
Oesterheld
Volker
V
Stümpflen
Arnaud
A
Ceol
Andrew
A
Chatr-aryamontri
John
J
Armstrong
Peter
P
Woollard
John J
JJ
Salama
Susan
S
Moore
Jérôme
J
Wojcik
Gary D
GD
Bader
Marc
M
Vidal
Michael E
ME
Cusick
Mark
M
Gerstein
Anne-Claude
AC
Gavin
Giulio
G
Superti-Furga
Jack
J
Greenblatt
Joel
J
Bader
Peter
P
Uetz
Mike
M
Tyers
Pierre
P
Legrain
Stan
S
Fields
Nicola
N
Mulder
Michael
M
Gilson
Michael
M
Niepmann
Lyle
L
Burgoon
Javier
J
De Las Rivas
Carlos
C
Prieto
Victoria M
VM
Perreau
Chris
C
Hogue
Hans-Werner
HW
Mewes
Rolf
R
Apweiler
Ioannis
I
Xenarios
David
D
Eisenberg
Gianni
G
Cesareni
Henning
H
Hermjakob
D030562:Databases, Protein / Q000592:standards*; D017408:Guidelines as Topic; D006801:Humans; D016247:Information Storage and Retrieval / Q000592:standards*; D038622:Internationality; D025941:Protein Interaction Mapping / Q000592:standards*; D040901:Proteomics / Q000592:standards*; D012106:Research / Q000592:standards*