[Uvulopalatopharyngoplasty and maxillomandibular advancement for obese patients with obstructive sleep apnea hypopnea syndrome: a preliminary report].
OBJECTIVE
To evaluate the feasibility and the results of the procedure of maxillomandibular advancement combined with uvulopalatopharyngoplasty for the treatment of obstructive sleep apnea hypopnea syndrome (OSAHS).


METHODS
Nine cases of obese patients with severe OSAHS [age (47.8 +/- 9.7); body mass index (BMI) (35.3 +/- 2.5) kg/m(2); apnea and hypopnea index (AHI) (88.7 +/- 6.7) per hour] underwent the procedure of maxillomandibular advancement (MMA) combined with uvulopalatopharyngoplasty (UPPP). The patients were monitored by polysomnography (PSG) before operation and 3, 6, 12 months after operation, and cephalometric analysis and velopharyngeal closure function were evaluated at the same time.


RESULTS
The maxilla was advanced by (8.3 +/- 1.3) mm and the mandible and chin were advanced by (23.0 +/- 2.2) mm. AHI was (2.1 +/- 1.1) per hour post-operation. All patients had no speaking problem and swallowing difficulty and had a good appearance and occlusions. The OSAHS in this group of patients was cured.


CONCLUSIONS
Good short-term effects were observed with UPPP and MMA in the treatment of obese patients with severe OSAHS. It did not cause the velopharyngeal closure insufficiency and maxillary necrosis. A long-term follow-up is needed.
Department of Oral and Maxillofacial Surgery, School of Stomatology; Ninth People's Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200011, China. lukeluxf@hotmail.com
Xiao-feng
XF
Lu
Min
M
Zhu
Jian-de
JD
He
Rui
R
Zhang
Zhi-yao
ZY
Li
Hong-xia
HX
Sun
D000328:Adult; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D019186:Mandibular Advancement / Q000379:methods*; D008875:Middle Aged; D009765:Obesity / Q000150:complications / Q000601:surgery*; D019340:Osteotomy, Le Fort; D010160:Palate, Soft / Q000601:surgery*; D010609:Pharyngeal Muscles / Q000601:surgery; D020181:Sleep Apnea, Obstructive / Q000150:complications / Q000601:surgery*; D016896:Treatment Outcome; D014609:Uvula / Q000601:surgery*