The one-pot synthesis of dextran-based nanoparticles and their application in in-situ fabrication of dextran-magnetite nanocomposites.
The dextran-based nanoparticles containing carboxyl groups were synthesized by a one-pot approach, without using any organic solvents and surfactants. The resultant dextran-based nanoparticles was used as a host for the growing and organization of Fe(3)O(4) nanoparticles. The approach consists of the mixture of ferrous/ferric ions aqueous solution and host nanoparticles and subsequent coprecipitation of ferrous/ferric ions in basic medium. The magnetic nanocomposite material obtained was characterized using transmission electron microscopy (TEM), dynamic light scattering (DLS), thermogravimetric analysis (TGA), X-ray diffraction techniques (XRD) and vibrating sample magnetometry (VSM). The data demonstrate that the carboxyls which can capture cationic ferrous/ferric by electronic interaction in the dextran-based hosts plays a crucial role in fabricating nanocomposites with a homogeneous spatial distribution of magnetite nanoparticles. The magnetic nanocomposites exhibit comparable saturation magnetizations to that of reported Fe(3)O(4) nanoparticles, and therefore display great potential in a large scope of biomedical fields.
Dou
Hongjing
H
Shanghai Jiao Tong University, P.R. China.
Xu
Bin
B
Tao
Ke
K
Tang
Minhua
M
Sun
Kang
K
D001672:Biocompatible Materials / Q000737:chemistry*; D003460:Crystallization / Q000379:methods*; D003911:Dextrans / Q000737:chemistry*; D052203:Ferrosoferric Oxide / Q000737:chemistry*; D046911:Macromolecular Substances / Q000737:chemistry; D008422:Materials Testing; D008968:Molecular Conformation; D049329:Nanostructures / Q000737:chemistry* / Q000648:ultrastructure*; D036103:Nanotechnology / Q000379:methods*; D010316:Particle Size; D013499:Surface Properties
D001672:Biocompatible Materials; D003911:Dextrans; D046911:Macromolecular Substances; D052203:Ferrosoferric Oxide