Chloroquine-induced recurrent psychosis.
Chloroquine is a commonly prescribed antimalarial drug that is widely used for the presumptive treatment of malaria in India. It has rarely been reported to cause psychosis, and to the best of our knowledge, recurrent psychosis due to chloroquine use has been reported only once, in 1996. We are reporting the second case of chloroquine-induced recurrent psychosis. We also discuss some of the possible neurobiological mechanisms leading to this neurotoxic adverse effect and our recommendations for future use of this drug.
Central Institute of Psychiatry, Ranchi, India.
Saddichha
S
Sahoo
Manoj
M
Kumar
Vinod K
VK
Sinha
D000328:Adult; D000962:Antimalarials / Q000009:adverse effects* / Q000627:therapeutic use; D002738:Chloroquine / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D007194:India; D008288:Malaria / Q000188:drug therapy; D008297:Male; D011605:Psychoses, Substance-Induced / Q000209:etiology*; D012008:Recurrence
D000962:Antimalarials; D002738:Chloroquine