[Clinical significance of inflammation markers in abdominal sepsis patients].
Possibilities of using C-reactive protein (CRP), procalcitonin (PCT), interleukin-6 (IL-6), lactoferrin (LF) and sorption ability of erythrocytes (SAE) as markers of the severity, prognosis and criteria of effectiveness of treatment were studied in 334 patients with abdominal sepsis. The investigation of the sepsis marker dynamics has shown that fast kinetics of CRP and PCT makes it impossible to assess the prognosis and effectiveness of treatment using these markers. IL-6, LF and SAE are the only ones to be used for this purpose.
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D015415:Biomarkers; D002097:C-Reactive Protein / Q000378:metabolism*; D002116:Calcitonin / Q000097:blood / Q000378:metabolism*; D015740:Calcitonin Gene-Related Peptide; D005260:Female; D006801:Humans; D015850:Interleukin-6 / Q000097:blood / Q000276:immunology*; D007813:Laparotomy / Q000401:mortality; D008297:Male; D008875:Middle Aged; D010538:Peritonitis / Q000276:immunology* / Q000378:metabolism* / Q000601:surgery; D011498:Protein Precursors / Q000097:blood / Q000378:metabolism*; D018805:Sepsis / Q000276:immunology / Q000378:metabolism; D012720:Severity of Illness Index; D015996:Survival Rate
D015415:Biomarkers; C000606589:CALCA protein, human; D015850:Interleukin-6; D011498:Protein Precursors; D002116:Calcitonin; D002097:C-Reactive Protein; D015740:Calcitonin Gene-Related Peptide