Signaling pathways and preimplantation development of mammalian embryos.
The mammalian preimplantation embryo is a critical and unique stage in embryonic development. This stage includes a series of crucial events: the transition from oocyte to embryo, the first cell divisions, and the establishment of cellular contacts. These events are regulated by multiple signal-transduction pathways. In this article we describe patterns of stage-specific expression in several signal-transduction pathways and try to give a profile of the signaling transduction network in preimplantation development of mammalian embryo.
School of Life Science and Biotechnology, Shanghai Jiao Tong University, China.
Yong
Y
Zhang
Zhaojuan
Z
Yang
Ji
J
Wu
D000818:Animals; D001755:Blastocyst; D008322:Mammals / Q000196:embryology* / Q000502:physiology; D015398:Signal Transduction