[Analysis of surgical treatment of coronary artery disease with mitral regurgitation].
OBJECTIVE
To analyze the effect of combined coronary artery with mitral valve surgery and summarize our clinical experience.


METHODS
From August, 2002 to May, 2006, 42 patients underwent combined CABG and mitral valve surgery because of concomitant ischemia myocardium disease and mitral regurgitation (MR) of moderate to severe degree. The etiology of MR was ischemic myocardium disease in 38 (90.48%, 38/42), rheumatic heart disease in 2(4.76%, 2/42)and degenerative valve disease in 2(4.76%, 2/42). Preoperative eject fraction (EF) was 0.20-0.80 (mean 0.41+/-0.14).Of all the patients 12 cases underwent mitral valve replacement and 30 mitral valvuloplasty.


RESULTS
After surgery 4 (9.52%,4/42) patients died in hospital. 36 patients were discharged with trivial to mild MR and 2 with moderate MR which had been severe preoperatively. The mean EF shows no significant improvement in discharged patients (0.41+/-0.14 preoperative versus 0.45+/-0.12 postoperative, P=0.152). But in MVP group, significant difference could be found (0.36+/-0.08) preoperative versus 0.41+/-0.10 postoperative, P=0.013).


CONCLUSIONS
Coronary artery disease and mitral valve insufficiency could be effectively corrected by combined CABG and mitral valve procedure. MVP is preferred and annuloplasty ring involvement could ensure effect of operation.
Department of Cardiac Surgery, Peking University First Hospital, Beijing 100034, China.
Lu Feng
LF
Zhang
Feng
F
Xiao
Yan
Y
Li
Jin
J
Wang
Yang
Y
Yang
Zhi Hun
ZH
Shi
D000328:Adult; D000368:Aged; D003324:Coronary Artery Disease / Q000150:complications / Q000601:surgery*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D008944:Mitral Valve Insufficiency / Q000150:complications / Q000601:surgery*; D016896:Treatment Outcome