A mechano-acoustic model of the effect of superior canal dehiscence on hearing in chinchilla.
Superior canal dehiscence (SCD) is a pathological condition of the ear that can cause a conductive hearing loss. The effect of SCD (a hole in the bony wall of the superior semicircular canal) on chinchilla middle- and inner-ear mechanics is analyzed with a circuit model of the dehiscence. The model is used to predict the effect of dehiscence on auditory sensitivity and mechanics. These predictions are compared to previously published measurements of dehiscence related changes in chinchilla cochlear potential, middle-ear input admittance and stapes velocity. The comparisons show that the model predictions are both qualitatively and quantitatively similar to the physiological results for frequencies where physiologic data are available. The similarity supports the third-window hypothesis of the effect of superior canal dehiscence on auditory sensitivity and mechanics and provides the groundwork for the development of a model that predicts the effect of superior canal dehiscence syndrome on auditory sensitivity and mechanics in humans.
Eaton-Peabody Laboratory of Auditory Physiology, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts 02114, USA. jocelyns@paradoxical.net
Jocelyn E
JE
Songer
John J
JJ
Rosowski
D000818:Animals; D002682:Chinchilla; D004424:Ear Canal / Q000033:anatomy & histology / Q000473:pathology / Q000502:physiology*; D007758:Ear, Inner / Q000033:anatomy & histology / Q000502:physiology* / Q000503:physiopathology; D006309:Hearing / Q000502:physiology*; D006311:Hearing Disorders / Q000503:physiopathology; D034381:Hearing Loss / Q000503:physiopathology; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008953:Models, Anatomic; D023421:Models, Animal