Effect on fertility of human chorionic gonadotrophin and uterine lavage with oxytocin performed after mating in Arabian barren mares.
The objective of the present study was to evaluate the beneficial effect of hCG injected immediately after mating in Arabian barren mares treated with uterine lavage and oxytocin. Arabian barren mares (n=36) with PMIE were subjected to detailed clinical examinations including palpation per rectum, vaginoscopy, and cytological examination. After mating the 36 mares were randomly divided into four groups. The mares in group 1 (n=10) were immediately after breeding injected with hCG 3,000 IU IM. Uterine lavage with 1L of N-saline containing 4 million IU of crystalline penicillin and 4 g of streptomycin sulphate was performed 4h after breeding. Then mares received two injections of oxytocin 40 IU IM 2h apart after 6h of mating. Mares in group 2 (n=10) treated with uterine lavage and oxytocin as group 1. While mares in group 3 (n=10) received uterine lavage only. A control group (n=6) as group 4 did not received any treatment. The results of clinical examination indicated that 69.4% of PMIE mares were harboring severe endometritis and 30.6% with a moderate form of endometritis. Significant (P<0.01) increase in lymphocytes were founded in barren mares included in this study. Higher pregnancy rate (P<0.01) was founded in Arabian barren mares 80% injected with hCG immediately after breeding and uterine lavage and oxytocin. No significant difference was found in mares received uterine lavage and oxytocin and uterine lavage only. In a conclusion, administration of hCG immediately after mating and intrauterine lavage containing antibiotics performed 4h and two injections of oxytocin 40 IU IM 2h apart after 6h of mating had improved fertility of Arabian barren mares.
Department of Surgery and Obstetrics, College of Veterinary, Medicine, University of Mosul, Mosul, Iraq. azawihh@yahoo.com
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D000818:Animals; D006063:Chorionic Gonadotropin / Q000494:pharmacology* / Q000627:therapeutic use; D004716:Endometritis / Q000209:etiology / Q000517:prevention & control; D005260:Female; D005298:Fertility / Q000187:drug effects*; D006736:Horses; D010121:Oxytocin / Q000008:administration & dosage / Q000494:pharmacology; D011247:Pregnancy; D018873:Pregnancy Rate; D011270:Pregnancy, Animal / Q000187:drug effects; D012726:Sexual Behavior, Animal / Q000187:drug effects* / Q000502:physiology; D014599:Uterus / Q000187:drug effects*; D044364:Vaginal Douching / Q000379:methods / Q000662:veterinary
D006063:Chorionic Gonadotropin; D010121:Oxytocin