Proteomic analysis of peritoneal fluid in women with endometriosis.
This study aims to evaluate differences in the expression of proteins present in the peritoneal fluid (PF) of women with and without endometriosis. PF samples were subjected to two-dimensional gel electrophoresis; protein spots of interest were identified by liquid chromatography tandem mass spectrometry. Several molecules had aberrant expression in PF of women with endometriosis; they may be useful for a better understanding of the pathogenesis of this disease.
Ferrero
Simone
S
Reproductive Physiology Laboratory, St. Bartholomew's School of Medicine & Dentistry, Queen Mary University of London, United Kingdom.
Gillott
David J
DJ
Remorgida
Valentino
V
Anserini
Paola
P
Leung
Kit-Yi
KY
Ragni
Nicola
N
Grudzinskas
Jurgis G
JG
D000328:Adult; D001202:Ascitic Fluid / Q000378:metabolism*; D002853:Chromatography, Liquid; D015180:Electrophoresis, Gel, Two-Dimensional / Q000379:methods; D004715:Endometriosis / Q000378:metabolism*; D005260:Female; D006801:Humans; D006863:Hydrogen-Ion Concentration; D013058:Mass Spectrometry / Q000379:methods; D008597:Menstrual Cycle; D040901:Proteomics / Q000379:methods*; D016622:Silver Staining