Enhanced frequency discrimination in hearing-impaired individuals: a review of perceptual correlates of central neural plasticity induced by cochlear damage.
Cochlear damages have been shown to induce changes in tonotopic maps in the central auditory system of animals; neurons deprived from peripheral inputs start to respond to stimuli with frequencies close to the cutoff frequency (Fc) or "edge" of the hearing loss, which then become over-represented at the neural level. Here, we review findings, which reveal a possible psychophysical correlate of such central over-representation in human listeners with sensorineural hearing loss. These findings concur to demonstrate a local improvement in difference limens for frequency (DLFs) at or near Fc. This effect has now been observed in several studies and subjects with varied audiometric characteristics, including high- and low-frequency, and symmetric and asymmetric hearing losses. The presence of cochlear dead region or a steeply sloping hearing loss appear as a necessary condition for its occurrence. The effect cannot be explained simply by more prominent loudness cues or spontaneous otoacoustic emissions (SOAEs) near the audiogram edge. Overall, the data are consistent with local changes in pitch discrimination performance near the hearing-loss cutoff frequency being a result of the neural over-representation of that frequency region in the central auditory system. Further work is needed to confirm this hypothesis, and investigate other possible perceptual correlates of injury-related cortical plasticity in both humans and animals.
Université de Lyon, Lyon F-69003, France. hung.thai-van@chu-lyon.fr
Hung
H
Thai-Van
Christophe
C
Micheyl
Arnaud
A
Norena
Evelyne
E
Veuillet
Damien
D
Gabriel
Lionel
L
Collet
D001307:Auditory Perception; D001921:Brain / Q000503:physiopathology*; D003051:Cochlea / Q000473:pathology*; D004192:Discrimination, Psychological; D006311:Hearing Disorders / Q000473:pathology / Q000503:physiopathology* / Q000523:psychology*; D006801:Humans; D009473:Neuronal Plasticity; D013061:Speech Acoustics