[Endoscopic methods of gastro-esophageal reflux disease (GERD) treatment and their complications].
Tretament in gastro-esophageal reflux disease (GERD) is in constant change. It is caused by the fact of change and development of diagnostic and therapeutic methods. Alternative methods of treatment are still searched beacause patients do not accept many years long drug treatment or surgical procedures. New methods are developed. Some of them as endoscopic fundoplication or methods of polimerizing substances injection in the area of lower esophageal sphincer have been abandoned because of low quickly diminishing efficacy Endoscopic sewing that implicate all layers of gaster is still under clinical trials and is considered as interesting. Stertt's procedure that is based on electromagnetic wave application in the area of lower esophageal sphincter is used in clinical practice. Despite effective methods of diagnosing and treatment of GERD there is no evidence of lowering incidence of complications of GERD. It is still common to find esophagus stricture as the first illness manifastation. Chronic character of GERD is associated with intestinal metaplasia and adenocarcinoma of the esophagus in its distal part. The most effective endoscopic methods of the treatment include: endoscopic dilation of the strictures and endoscopic methods of patological epithelium removal in Barrett's esophagus. These are: photodynamic therapy, argon coagulation, laser thermoablation, multipolar ablation and endoscpic mucosectomy. The paper is the review of the methods aimed at GERD and its complication treatment.
Wojskowy Instytut Medyczny w Warszawie, Klinika Gastroenterologii CSK MON.
Jerzy
J
Gil
Antoni
A
Błaszak
Stanisław
S
Wojtuń
Marek
M
Wojtkowiak
D000818:Animals; D001471:Barrett Esophagus / Q000473:pathology / Q000601:surgery; D004724:Endoscopy / Q000379:methods*; D004943:Esophagogastric Junction / Q000473:pathology / Q000601:surgery; D018662:Fundoplication / Q000379:methods; D005764:Gastroesophageal Reflux / Q000150:complications* / Q000175:diagnosis / Q000628:therapy*; D006801:Humans; D017075:Laser Coagulation; D053685:Laser Therapy; D008679:Metaplasia; D018670:Monitoring, Ambulatory; D011183:Postoperative Complications; D054328:Proton Pump Inhibitors; D017494:Proton Pumps / Q000187:drug effects
D054328:Proton Pump Inhibitors; D017494:Proton Pumps