[Value of CT enhancement degree in differential diagnosis between pancreatic carcinoma and inflammatory pancreatic mass].
OBJECTIVE
To compare the CT enhancement degree in pancreatic carcinoma (PC) and inflammatory pancreatic mass (IPM), and to study the diagnostic value of CT to these two diseases.


METHODS
Eighty-five patients with PC or IPM, 47 males and 38 females, aged 62 (37-79), underwent plain CT scanning and enhanced CT scanning in pancreatic phase and delay phase. The CT values of the pancreatic mass and relative normal pancreatic tissue were measured. The diagnosis of PC and IPM was verified by operation, biopsy, etc. Sixty persons without pancreatic diseases were used as controls.


RESULTS
Among the 85 patients, 66 were proved to be with PC, and 19 patients were proved to be with IPM. In plain CT scanning, pancreatic-phase CT enhancement, and delay-phase CT enhancement, the CT values of PC were (34+/-7) HU, (54+/-10) HU, and (61+/-14) HU respectively; and the CT values of the relatively normal pancreatic tissue were (42+/-6) HU, (105+/-12) HU, and (77+/-10) HU respectively. In plain CT scanning, pancreatic-phase CT enhancement, and delay-phase CT enhancement, the CT values of IPM were (37+/-6) HU, (58+/-17) HU, and (64+/-10) HU respectively; and the CT values of the relatively normal pancreatic tissue were (40+/-8) HU, (85+/-10) HU, and (72+/-9) HU respectively. The pancreatic-phase enhanced CT values of the mass in the PC group and the IPM group showed no remarkable differences (P>0.05). The pancreatic-phase enhancement intensity of the relatively normal pancreatic tissue is greater in PC than in IPM (P<0.01).


CONCLUSIONS
There is a certain limit for CT enhancement in differentiating between PC and IPM. Comprehensive analysis is necessary in diagnosis of PC and IPM.
Department of Medical Imaging, Jinling Hospital Medical School, Nanjing 210002, China.
Zhong-qiu
ZQ
Wang
Guang-ming
GM
Lu
Ying-xin
YX
Chen
Jiang
J
Wu
Zhu-fu
ZF
Quan
Jie-shou
JS
Li
D000328:Adult; D000368:Aged; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010190:Pancreatic Neoplasms / Q000175:diagnosis / Q000000981:diagnostic imaging*; D010195:Pancreatitis / Q000175:diagnosis / Q000000981:diagnostic imaging*; D011856:Radiographic Image Enhancement; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed / Q000379:methods*