Total synthesis of (+/-)-joubertinamine from 3-(3,4-dimethoxyphenyl)-5-bromo-2-pyrone.
The regioselective synthesis and Diels-Alder cycloaddition of 3-(3,4-dimethoxyphenyl)-5-bromo-2-pyrone provided a new efficient synthetic route to joubertinamine (9.6% total yield over 10 steps).
Department of Chemistry, Hanyang University, Seoul, Korea 133-791.
Nguyen Thanh
NT
Tam
Cheon-Gyu
CG
Cho
D000470:Alkaloids / Q000737:chemistry; D026121:Indole Alkaloids / Q000138:chemical synthesis*; D011753:Pyrones / Q000737:chemistry*; D013237:Stereoisomerism
D000470:Alkaloids; D026121:Indole Alkaloids; D011753:Pyrones; C523380:joubertinamine