Use of recombinant factor VIIa in a preterm infant with coagulopathy and subdural hematoma.
Activated recombinant factor VIIa was administered to a preterm infant with bleeding diasthesis and a huge subdural hematoma that could not be controlled by the blood products. The coagulation tests were normalized the following day. Recombinant factor VIIa can be a choice in selected cases with intractable bleedings unesponsive to conventional replacement therapy.
Department of Pediatrics, Divisions of Neonatology and Hematology, School of Medicine, Marmara University, Istanbul, Turkey. emelkayrak@yahoo.com
Emel
E
Altuncu
Su
S
Berrak
Hülya
H
Bilgen
Ziya
Z
Yurdakul
Cengiz
C
Canpolat
Eren
E
Ozek
D016913:Blood Component Transfusion; D002543:Cerebral Hemorrhage / Q000628:therapy*; D005167:Factor VII / Q000627:therapeutic use*; D015942:Factor VIIa; D006408:Hematoma, Subdural / Q000628:therapy*; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D007235:Infant, Premature, Diseases / Q000628:therapy*; D008297:Male; D010949:Plasma; D011994:Recombinant Proteins / Q000627:therapeutic use
D011994:Recombinant Proteins; D005167:Factor VII; C103587:recombinant FVIIa; D015942:Factor VIIa