Acupuncture at GV01 relieves somatic pain referred by colitis in rats.
The present study aimed to expand our previous findings regarding the therapeutic effects and underlying mechanisms of acupuncture at GV01 in colitis. Our results showed that acupuncture at GV01 has antinociceptive effects on referred somatic pain induced by experimental colitis, and that endogenous opioid pathways may mediate these effects.
Kim
Hee-Young
HY
Department of Neuroscience and Cell Biology, University of Texas Medical Branch, Galveston, TX 77555-1069, USA.
Hahm
Dae-Hyun
DH
Chae
Younbyoung
Y
An
Kyungeh
K
Pyun
Kwang-Ho
KH
Lee
Hyejung
H
Shim
Insop
I
D015669:Acupuncture Points; D015670:Acupuncture Therapy / Q000379:methods*; D000818:Animals; D003092:Colitis / Q000139:chemically induced / Q000150:complications / Q000628:therapy*; D007150:Immunohistochemistry; D008297:Male; D009270:Naloxone / Q000494:pharmacology; D009474:Neurons / Q000187:drug effects / Q000378:metabolism; D017288:Pain Threshold / Q000187:drug effects; D053591:Referred Pain / Q000209:etiology / Q000503:physiopathology / Q000628:therapy*; D010487:Periaqueductal Gray / Q000187:drug effects / Q000378:metabolism; D016760:Proto-Oncogene Proteins c-fos / Q000378:metabolism; D011897:Random Allocation; D051381:Rats; D017207:Rats, Sprague-Dawley; D013997:Time Factors; D014302:Trinitrobenzenesulfonic Acid / Q000633:toxicity
D016760:Proto-Oncogene Proteins c-fos; D009270:Naloxone; D014302:Trinitrobenzenesulfonic Acid