A comparative study between ketorolac and ketoprofen in postoperative pain after uvulopalatopharyngoplasty.
Postoperative pain is a serious problem, requiring an appropriate response from the medical doctor. In otolaryngology special attention is needed after uvulopalatopharyngoplasty (UP3).


OBJECTIVE
To compare the efficacy of postoperative analgesia using ketorolac and ketoprofen after UP3.


METHODS
A prospective, randomized, double-blind study was made of 24 patients that were divided into 2 groups (14 received ketorolac and 10 received ketoprofen). Pain intensity was based on an analog visual scale and the need for opioids (tramadol).


RESULTS
Of the 13 patients that received ketorolac, 3 (21%) required opioids; 7 of 10 (70%) patients in ketoprofen group used opioids. 12 hours after surgery, 71% of the patients that received ketorolac had mild or absence of pain. 70% of the ketoprofen users reported moderate to significant pain. 24 hours after surgery, 60% of the patients using ketoprofen reported moderate to significant pain, while 86% of the ketorolac users reported mild or absence of pain.


CONCLUSIONS
We concluded that ketorolac is more effective compared to ketoprofen in the treatment of immediate postoperative pain after UP3, as patients using ketorolac had less pain and used opioids to a lesser degree.
Patrocínio
Lucas Gomes
LG
Otorhinolaryngology Unit of the Uberlandia Federal University Medical School. lucaspatrocinio@triang.com.br
Rangel
Marcelo de Oliveira
Mde O
Marques Miziara
Gustavo Sousa
GS
Rodrigues
Alexandre Menezes
AM
Patrocínio
José Antonio
JA
Patrocinio
Tomas Gomes
TG
D000701:Analgesics, Opioid / Q000627:therapeutic use; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use*; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D007660:Ketoprofen / Q000627:therapeutic use*; D020910:Ketorolac / Q000627:therapeutic use*; D008297:Male; D010147:Pain Measurement; D010149:Postoperative Pain / Q000188:drug therapy*; D010160:Palate, Soft / Q000601:surgery*; D010614:Pharynx / Q000601:surgery*; D011446:Prospective Studies; D014147:Tramadol / Q000627:therapeutic use; D014609:Uvula / Q000601:surgery
D000701:Analgesics, Opioid; D000894:Anti-Inflammatory Agents, Non-Steroidal; D014147:Tramadol; D007660:Ketoprofen; D020910:Ketorolac