Oligohydramnios in a pregnant woman with Cushing's syndrome caused by an adrenocortical adenoma.
A 28-year-old primigravida with severe oligohydramnios and pre-eclamptic symptoms was found to have Cushing's syndrome caused by an adrenocortical tumor. After maternal therapy the amniotic volume normalised, but the fetus succumbed. As clinical features of pre-eclampsia and Cushing's syndrome may overlap, diagnosis can be delayed or even missed.
Department of Obstetrics and Gynaecology, Leiden University Medical Centre, Leiden, The Netherlands. pcmdegroot@yahoo.co.uk
Pieter C M
PC
De Groot
Inge L
IL
Van Kamp
Evert J K
EJ
Zweers
Cor D
CD
De Kroon
Willem J
WJ
Van Wijngaarden
D000236:Adenoma / Q000150:complications / Q000175:diagnosis / Q000601:surgery; D000306:Adrenal Cortex Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D000315:Adrenalectomy; D000328:Adult; D003480:Cushing Syndrome / Q000175:diagnosis* / Q000209:etiology; D003937:Diagnosis, Differential; D005260:Female; D005313:Fetal Death; D006801:Humans; D006854:Hydrocortisone / Q000627:therapeutic use; D016104:Oligohydramnios / Q000175:diagnosis* / Q000209:etiology; D011225:Pre-Eclampsia; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000175:diagnosis*
D006854:Hydrocortisone