[Endocrine disorders in HCV infection].
Thyroid disorders and diabetes mellitus t. II are the most common disorders observed among of endocrine extrahepatic manifestations of HCV infection. The mechanism of this disorders is still unclear. Two main hypothesis are considered: primary cytopathic effect of virus and secondary-induced autoimmunity. The ability of HCV to infect central nervous system cells seems to be significant in the hypothalamus--epiphysis--axis dysfunction. Further clinical researches are awaited in order to explain phenomenon mentioned above.
Piszko
Paweł
P
Katedra i Klinika Chorób Zakaźnych, Chorób Watroby i Nabytych Niedoborów Odpomościowych, Akademii Medycznej we Wrocławiu. pawelp@generacja.net
Fleischer
Katarzyna
K
Simon
Krzysztof
K
Serafińska
Sylwia
S
D001327:Autoimmune Diseases / Q000821:virology*; D002490:Central Nervous System / Q000821:virology; D003924:Diabetes Mellitus, Type 2 / Q000821:virology*; D016174:Hepacivirus / Q000302:isolation & purification*; D019698:Hepatitis C, Chronic / Q000150:complications*; D006801:Humans; D007030:Hypothalamo-Hypophyseal System / Q000821:virology; D013959:Thyroid Diseases / Q000821:virology*