[Comparison of the clinical therapeutic effects between local injection of pingyangmycin and sodium morrhuate on oral and maxillofacial venous malformation].
OBJECTIVE
To observe and compare the curative effect of pingyangmycin and sodium morrhuae respectively in the treatment of oral and maxillofacial venous malformation.


METHODS
Forty cases of oral and maxillofacial venous malformation were induced in this study, 20 of which were given local injection of low dose of pingyangmycin, and 20 given local injection of 5% sodium morrheate. The therapeutic effects were observed.


RESULTS
The effective cases of pingyangmycin was 19, and the effective cases of sodium morrhuate was 12. The side effect was found in 10 cases of, and in 15 cases sodium morrhuate group, the former was mainly pingymangmycin group systemic, the later was mainly local. The difference was significant between the two groups (P < 0.05).


CONCLUSIONS
Pingyangmycin is more effective in effective rate and side effect treatment of venous hemangioma than sodium morrhuate.
Department of Oral and Maxillofacial Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China. hewei1968@tom.com
Wei
W
He
Ai-Ling
AL
Gu
Jun-Lan
JL
Shang
D000293:Adolescent; D000328:Adult; D001761:Bleomycin / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D015552:Injections, Intralesional; D008297:Male; D008875:Middle Aged; D012597:Sclerosing Solutions / Q000627:therapeutic use*; D012976:Sodium Morrhuate / Q000008:administration & dosage* / Q000627:therapeutic use; D016896:Treatment Outcome; D054079:Vascular Malformations / Q000628:therapy*; D055815:Young Adult
D012597:Sclerosing Solutions; D001761:Bleomycin; C025703:bleomycetin; D012976:Sodium Morrhuate