[The reaction of hormones of hypophysis-thyroid gland's endocrinal axis on vibration pathology and on condition of it's correction with liquid oxygen and anabolic steroids].
The experiment was held on white male rats. After the tests had been finished, by means of immunofermental method the concentration of thyroid (T3 and T4) and thyrotrophic (TSH) hormones were defined in the blood of animals in condition of vibropathology and it's correction with liquid oxygen and retabolil. The research showed, that the level of TSH, T3 and T4 decreased in condition of vibropathology and it's correction with anabolic steroid compare with control groups. But against of background liquid oxygen's injection the level of TSH increased, but the concentration of T3 and T4 were reduced compare with control group, though they were increased compare with the rest groups of experimental animals. As a result of the search, it was established, that the impact of vibration on the organism of male rats causes important changes in the hypophysis-thyroid gland's endocrinal axis, particularly it takes place the hypofunction of thyroid gland. And it's worth to mention that the correction of vibropathology with liquid oxygen cause positive influence and changes in the organism. There is a positively expressed normalization of thyroid and thyrotrophic hormones' concentration, but the correction of vibropathology with anabolic steroid has not been a successful one.
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D045930:Anabolic Agents / Q000494:pharmacology*; D000818:Animals; D007030:Hypothalamo-Hypophyseal System / Q000187:drug effects* / Q000503:physiopathology*; D008297:Male; D010100:Oxygen / Q000494:pharmacology* / Q000627:therapeutic use*; D010902:Pituitary Gland / Q000187:drug effects* / Q000503:physiopathology*; D010913:Pituitary-Adrenal System / Q000187:drug effects* / Q000503:physiopathology*; D051381:Rats; D013961:Thyroid Gland / Q000187:drug effects* / Q000503:physiopathology*; D013963:Thyroid Hormones / Q000378:metabolism*; D014732:Vibration / Q000009:adverse effects*
D045930:Anabolic Agents; D013963:Thyroid Hormones; D010100:Oxygen