Tracheal replacements: part 1.
In this review, we summarize the history of tracheal reconstruction and replacement as well as progress in current tracheal substitutes. In Part 1, we cover the historical highlights of grafts, flaps, tube construction, and tissue transplants and address the progress made in tracheal stenting as a means of temporary tracheal support. This is followed in Part 2 by an analysis of solid and porous tracheal prostheses in experimental and clinical trials. We conclude Part 2 with a summary of recent efforts toward generating a bioengineered trachea. Finally, we provide an algorithm on the spectrum of options available for tracheal replacement.
Department of Surgery, University of Texas Medical Branch, Galveston, Texas 77555, USA.
Kristin A
KA
Kucera
Amy E
AE
Doss
Sarah S
SS
Dunn
Lindsey A
LA
Clemson
Joseph B
JB
Zwischenberger
D049673:History, 20th Century; D049674:History, 21st Century; D006801:Humans; D019736:Prostheses and Implants / Q000266:history; D019919:Prosthesis Implantation / Q000266:history*; D015607:Stents / Q000266:history*; D013524:Surgical Flaps / Q000266:history*; D023822:Tissue Engineering / Q000266:history*; D016378:Tissue Transplantation / Q000266:history*; D014132:Trachea / Q000601:surgery; D014182:Transplantation, Autologous