The heat shock proteins and plastic surgery.
Heat shock proteins are diverse and essential components of cell physiology. Their expression is elevated in the cell undergoing stress, where they protect the cell from death by necrosis or apoptosis and accelerate recovery. Significant advances have been made in studies relevant to plastic surgery regarding these proteins and their manipulation. This review introduces the heat shock proteins and appraises these studies in skin, ultraviolet light exposure, neoplasia, wound healing, ageing, burns, and reconstructive surgery.
Department of Plastic and Reconstructive Surgery, Nottingham City Hospital, Hucknall Road, Nottingham NG5 1PB, UK. m.wagstaff@doctors.org.uk
M J D
MJ
Wagstaff
M
M
Shah
D A
DA
McGrouther
D S
DS
Latchman
D002056:Burns / Q000503:physiopathology; D006360:Heat-Shock Proteins / Q000502:physiology*; D006801:Humans; D019651:Plastic Surgery Procedures; D012867:Skin / Q000378:metabolism; D013312:Stress, Physiological / Q000503:physiopathology; D013524:Surgical Flaps / Q000502:physiology; D018746:Systemic Inflammatory Response Syndrome / Q000503:physiopathology; D014945:Wound Healing / Q000502:physiology
D006360:Heat-Shock Proteins