Multicentric Bowen disease in linear porokeratosis.
Linear porokeratosis is a genodermatosis, caused by a clonal proliferation of keratinocytes along the lines of Blaschko. This type of porokeratosis is particularly susceptible to malignant degeneration e.g. to Bowen disease, a squamous cell carcinoma (SCC) in situ with the potential for significant lateral spread. Here we report a case of linear porokeratosis on the left leg of a 56-year-old man, complicated with two lesions of multicentric Bowen disease.
Guenova
Emmanuella
E
Department of Dermatology, Eberhard Karl University - Tübingen, Liebermeisterstr. 25, 72076 Tübingen, Germany. emmanuella.guenova@med.uni-tuebingen.de
Hoetzenecker
Wolfram
W
Metzler
Gisela
G
Röcken
Martin
M
Schaller
Martin
M
D001913:Bowen's Disease / Q000209:etiology* / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D017499:Porokeratosis / Q000150:complications* / Q000473:pathology; D012867:Skin / Q000473:pathology; D012878:Skin Neoplasms / Q000209:etiology* / Q000473:pathology