Arterial pulse waveform analysis by the probability distribution of amplitude.
Augmentation index (AIx) calculated from the pressure waveform of an artery is widely used to quantify the arterial stiffness and evaluate the cardiovascular risk. The key for calculating AIx is to locate the inflection point on the waveform signal, which is caused by the wave reflection. This study applies the probability distribution of the pressure waveform to identify the inflection point for estimating AIx. The results show that the pulse wave probability analysis not only can estimate AIx with a better tolerance of noise interference, but also allows for simultaneously monitoring, locating and characterizing other physiologically significant points on the pressure waveform.
Division of Mechanics, Research Center for Applied Sciences, Academia Sinica, Taipei 11529, Taiwan, Republic of China.
Po-Hsiang
PH
Tsui
Lian-Yu
LY
Lin
Chien-Chung
CC
Chang
Juey-Jen
JJ
Hwang
Jen-Jen
JJ
Lin
Chin-Chou
CC
Chu
Chiung-Nien
CN
Chen
King-Jen
KJ
Chang
Chien-Cheng
CC
Chang
D000465:Algorithms; D001158:Arteries / Q000502:physiology*; D001696:Biomechanical Phenomena; D002339:Carotid Arteries / Q000502:physiology; D003627:Data Interpretation, Statistical; D006801:Humans; D009131:Muscle, Smooth, Vascular / Q000502:physiology*; D011336:Probability