3-hydroxy fatty acids found in capsules of Cryptococcus neoformans.
Using immunofluorescence confocal laser scanning microscopy, immunogold transmission electron microscopy and gas chromatography--mass spectrometry, we demonstrated the presence of 3-hydroxy fatty acids in Cryptococcus neoformans. Our results suggest that these oxylipins accumulate in capsules where they are released as hydrophobic droplets through tubular protuberances into the surrounding medium.
UNESCO MIRCEN: Industrial Biotechnology, Department of Microbial, Biochemical and Food Biotechnology, University of the Free State, P.O. Box 339, Bloemfontein, South Africa.
Olihile M
OM
Sebolai
Carolina H
CH
Pohl
Piet J
PJ
Botes
Catharina J
CJ
Strauss
Pieter W J
PW
van Wyk
Alfred
A
Botha
Johan L F
JL
Kock
D003455:Cryptococcus neoformans / Q000737:chemistry* / Q000648:ultrastructure; D005227:Fatty Acids / Q000032:analysis* / Q000737:chemistry; D008401:Gas Chromatography-Mass Spectrometry; D006880:Hydroxy Acids / Q000032:analysis* / Q000737:chemistry; D018613:Microscopy, Confocal; D046529:Microscopy, Electron, Transmission
D005227:Fatty Acids; D006880:Hydroxy Acids