[Clinical and immunological manifestations of tuberculosis concurrent with HIV infection in the Kemerovo Region].
The clinical and immunological features of the course of pulmonary tuberculosis (PT) were studied in 418 patients with HIV infection. PT developed in the presence of HIV infection in 212 patients (Group 1), active PT was detected before HIV infection in 72 (Group 2), TB and HIV infection were concurrently diagnosed in 134 patients (Group 3). In the region, most patients with TB and HIV infection were found to have a moderately suppressed immune response. There was a high proportion of patients with disseminated TB in Groups 1 and 3 and those with chronic TB in Groups 2. In Groups 2 and 3, fibrocavernous PT was registered several times more frequently.
Makasheva
E V
EV
Konopchuk
O N
ON
Aksenova
V Ia
VIa
Ivanova
N I
NI
Chernykh
E R
ER
Kopylova
I F
IF
Safonov
A D
AD
D015415:Biomarkers; D015704:CD4 Antigens / Q000276:immunology*; D002391:Catchment Area, Health; D002908:Chronic Disease; D015897:Comorbidity; D015658:HIV Infections / Q000453:epidemiology*; D006684:HLA-DR Antigens / Q000276:immunology*; D059811:HLA-DRB1 Chains; D006801:Humans; D012426:Russia / Q000453:epidemiology; D014397:Tuberculosis, Pulmonary / Q000453:epidemiology* / Q000276:immunology*
D015415:Biomarkers; D015704:CD4 Antigens; D006684:HLA-DR Antigens; D059811:HLA-DRB1 Chains