Plantar keratoderma as a presenting sign of pancreatic adenocarcinoma.
A 76-year-old woman presented with a 1-year history of back pain and sudden onset of plantar keratoderma. Her serum carbohydrate antigen (CA 19.9) levels were elevated. Endoscopic radial sonographic examination led to the diagnosis of pancreatic adenocarcinoma, in a stage not detectable with helical CT yet amenable to surgical therapy. Cutaneous lesions disappeared after distal pancreatectomy.
Ulla
Jose Luis
JL
Department of Gastroenterology, Complexo Hospitalario de Pontevedra, Avda de Montecelo sn, Pontevedra 36001, Spain.
Garcia-Doval
Ignacio
I
Posada
Celia
C
Soto
Santiago
S
Alvarez
Carlos
C
Ledo
Luis
L
Vazquez-Astray
Enrique
E
D000230:Adenocarcinoma / Q000150:complications* / Q000000981:diagnostic imaging / Q000601:surgery; D000368:Aged; D003937:Diagnosis, Differential; D018450:Disease Progression; D019160:Endosonography / Q000379:methods*; D005260:Female; D006801:Humans; D007645:Keratoderma, Palmoplantar / Q000175:diagnosis / Q000209:etiology*; D010180:Pancreatectomy; D010190:Pancreatic Neoplasms / Q000150:complications* / Q000000981:diagnostic imaging / Q000601:surgery; D010257:Paraneoplastic Syndromes