Pulmonary hemodynamics and gas exchange in off pump coronary artery bypass grafting.
OBJECTIVE
To investigate the influence of cardiopulmonary bypass on pulmonary hemodynamics and gas exchange.


METHODS
Low risk patients admitted for elective coronary artery bypass grafting were randomized to either on (n=25) or off pump (n=25) surgery. Central hemodynamics, gas exchange, and venous admixture were studied during and up to 20 h after surgery.


RESULTS
There was no difference in pulmonary vascular resistance index (P=0.16), right ventricular stroke work index (P>0.2), mean pulmonary artery pressure (P>0.2) or pulmonary capillary wedge pressure (P>0.2) between groups. Soon after surgery there was a tendency towards higher cardiac index (P=0.07) in the off pump group. Arterial oxygen tension (P>0.2), hematocrit (P>0.2), venous admixture (P>0.2), and arterial-venous oxygen content difference (P=0.12) did not differ between groups.


CONCLUSIONS
This prospective, randomized study showed no difference in pulmonary hemodynamics, pulmonary gas exchange, and venous admixture, in low risk patients undergoing off pump compared to on pump coronary artery bypass surgery.
Department of Cardiothoracic Surgery and Anesthesia, Karolinska University Hospital, 171 76 Stockholm, Sweden. jenny.vedin@karolinska.se
Jenny
J
Vedin
Ulf
U
Jensen
Anders
A
Ericsson
Sten
S
Samuelsson
Jarle
J
Vaage