Anaphylactic shock in a beta-blocked child: usefulness of isoproterenol.
Like adults, children taking beta-blockers are at risk for serious hemodynamic instability in case of anaphylaxis. We report a case of severe bradycardia associated with anaphylactic shock after aprotinin in a beta-blocked child, which was resistant to intravenous epinephrine and vascular filling but was treated successfully with isoproterenol.
Department of Anesthesiology, Cliniques Universitaires Saint-Luc, Brussels, Belgium. mona.momeni@clin.ucl.ac.be
Mona
M
Momeni
Barbara
B
Brui
Philippe
P
Baele
Amine
A
Matta
D000318:Adrenergic beta-Agonists / Q000627:therapeutic use*; D000319:Adrenergic beta-Antagonists / Q000009:adverse effects*; D000707:Anaphylaxis / Q000150:complications / Q000188:drug therapy*; D000758:Anesthesia; D001020:Aortic Stenosis, Subvalvular / Q000601:surgery; D007611:Aprotinin / Q000009:adverse effects; D001283:Atrioventricular Node / Q000601:surgery; D001919:Bradycardia / Q000150:complications / Q000188:drug therapy; D002675:Child, Preschool; D004837:Epinephrine / Q000627:therapeutic use; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D007545:Isoproterenol / Q000627:therapeutic use*; D008297:Male; D010100:Oxygen / Q000097:blood; D015842:Serine Proteinase Inhibitors / Q000009:adverse effects; D014662:Vasoconstrictor Agents / Q000627:therapeutic use
D000318:Adrenergic beta-Agonists; D000319:Adrenergic beta-Antagonists; D015842:Serine Proteinase Inhibitors; D014662:Vasoconstrictor Agents; D007611:Aprotinin; D007545:Isoproterenol; D010100:Oxygen; D004837:Epinephrine