Thyrotoxic neuropathy- an under diagnosed condition.
Many neurological diseases like myopathy, periodic paralysis, ophthalmoplegia, and myasthenia gravis are known associations of thyrotoxicosis. However the association of neuropathy with thyrotoxicosis is not frequently recognized. First described by Charcot in 1889, thyrotoxic neuropathy or 'Basedow's Paraplegia' is a rarely reported entity. We describe here a case of a young woman with subacute distal neuropathy as the presenting manifestation of thyrotoxicosis. The neuropathy improved on antithyroid treatment. A careful literature search leads us to believe that peripheral neuropathy in thyrotoxicosis is under recognised. Thyroid function tests can be helpful in the diagnosis of this treatable neuropathy and should be included in the routine work up.
Department of Internal Medicine, Drexel University College of Medicine, Philadelphia, PA 19102, USA,
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V
Sahni
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Gupta
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Anuradha
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Tatke
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Kar
D005260:Female; D006801:Humans; D007194:India; D008875:Middle Aged; D010525:Peripheral Nerves / Q000473:pathology / Q000503:physiopathology; D011115:Polyneuropathies / Q000175:diagnosis* / Q000503:physiopathology; D013971:Thyrotoxicosis / Q000150:complications* / Q000503:physiopathology