Clinical-radiological correlation. Report of two cases.
Multiple system atrophy (MSA) is a sporadic, neurodegenerative disorder, clinically characterized by parkinsonian, autonomic, cerebellar and pyramidal signs. We describe two patients showing different presentations of the same disease. The patient on case 1 presents features of MSA-C or olivopontocerebellar atrophy with the pontine "cross sign" on brain MRI. The second case reports a patient presenting MSA-P or striatonigral degeneration and the brain MRI shows lenticular nucleus sign alteration. We think that brain MRI might increase the accuracy diagnostic of MSA.
Neurology Division, Internal Medicine Department, Hospital Universitário Antonio Pedro, Federal Fluminense University, Niterói RJ, Brazil.
Adolfo V de
AV
Albuquerque
Marcos R G de
MR
Freitas
Daniel
D
Cincinatus
Maria Beatriz B
MB
Harouche
D001921:Brain / Q000473:pathology*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009849:Olivopontocerebellar Atrophies / Q000473:pathology*; D020955:Striatonigral Degeneration / Q000473:pathology*