N-heterocyclic carbene catalyzed ring expansion of 4-formyl-beta-lactams: synthesis of succinimide derivatives.
N-heterocyclic carbene (NHC) has been employed as an efficient catalyst for ring expansion of 4-formyl-beta-lactams, allowing the facile synthesis of succinimide derivatives. This organocatalytic process features readily availability of the catalyst, low catalyst loading, and mild reaction conditions.
State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 354 Fenglin Lu, Shanghai 200032, China.
Gong-Qiang
GQ
Li
Yi
Y
Li
Li-Xin
LX
Dai
Shu-Li
SL
You