[Clinical differences between heart failure versus ischemic patients].
Heart failure represents a very common disease with high mortality, despite therapeutic and preventive measures. In order to evaluate the characteristics of heart failure patients, a case-control study was carried out, comparing sixty heart failure patients versus sixty patients who presented an evident atherosclerotic disease, but not heart failure. Among the differences we found, a higher heart rate, reduced levels of free-triiodothyronine and increased levels of serum uric acid in heart failure patients might directly contribute to its pathophysiology and represent potential therapeutic targets.
IV Divisione Medica, Azienda Ospedaliera-Universitaria Pisana, Pisa.
Massimiliano
M
Pinelli
Massimo
M
Bindi
Federica
F
Moroni
Javier
J
Rosada
Maido
M
Castiglioni
D000368:Aged; D000369:Aged, 80 and over; D050197:Atherosclerosis / Q000097:blood* / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy; D015415:Biomarkers / Q000097:blood; D016022:Case-Control Studies; D004562:Electrocardiography; D005260:Female; D006333:Heart Failure / Q000097:blood* / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy; D006339:Heart Rate; D006801:Humans; D008297:Male; D017202:Myocardial Ischemia / Q000097:blood* / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy; D012307:Risk Factors; D014284:Triiodothyronine / Q000097:blood; D014527:Uric Acid / Q000097:blood
D015415:Biomarkers; D014284:Triiodothyronine; D014527:Uric Acid