Clinical-radiological correlation. Report of two cases.
Multiple system atrophy (MSA) is a sporadic, neurodegenerative disorder, clinically characterized by parkinsonian, autonomic, cerebellar and pyramidal signs. We describe two patients showing different presentations of the same disease. The patient on case 1 presents features of MSA-C or olivopontocerebellar atrophy with the pontine "cross sign" on brain MRI. The second case reports a patient presenting MSA-P or striatonigral degeneration and the brain MRI shows lenticular nucleus sign alteration. We think that brain MRI might increase the accuracy diagnostic of MSA.
Albuquerque
Adolfo V de
AV
Neurology Division, Internal Medicine Department, Hospital Universitário Antonio Pedro, Federal Fluminense University, Niterói RJ, Brazil.
Freitas
Marcos R G de
MR
Cincinatus
Daniel
D
Harouche
Maria Beatriz B
MB
D001921:Brain / Q000473:pathology*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009849:Olivopontocerebellar Atrophies / Q000473:pathology*; D020955:Striatonigral Degeneration / Q000473:pathology*