Secretory A immunoglobulin, total proteins and salivary flow in Recurrent Aphthous Ulceration.
Clinical and experimental study. Introduction. Of debatable etiology, Recurrent Aphthous Ulcerations (R.A.U), is most of the time considered an immunological deficiency.


OBJECTIVE
The aim of this paper is to review the literature and clinical investigations regarding IgA-s, total proteins salivary concentration and basal salivary flow of patients with R.A.U. during activity and quiescence.


METHODS
Nephelometry was used to measure salivary IgA-s; Pyrogallol red was used for total salivary proteins and the gravimetrical analysis for salivary flow measurement.


RESULTS
Results demonstrated a significant increase in salivary IgA-s in active lesions in relation to quiescence. On the other hand, protein concentration rates were similar in both periods.


CONCLUSIONS
Salivary IgA-s can be used as a parameter to study the immune status of the oral mucosa.
Martinez
Kennedy de Oliveira
Kde O
Morphologic Sciences, University of Uberaba.
Mendes
Lauro Lúcio
LL
Alves
José Bento
JB
D000293:Adolescent; D000328:Adult; D002648:Child; D005260:Female; D006801:Humans; D007071:Immunoglobulin A, Secretory / Q000032:analysis*; D008297:Male; D008875:Middle Aged; D012008:Recurrence; D012307:Risk Factors; D012463:Saliva / Q000737:chemistry* / Q000502:physiology; D012471:Salivary Proteins and Peptides / Q000032:analysis*; D013281:Stomatitis, Aphthous / Q000276:immunology*
D007071:Immunoglobulin A, Secretory; D012471:Salivary Proteins and Peptides