Retropharyngeal neuroblastoma in a neonate: case report and literature review.
Primary cervical neuroblastoma (NB) in neonates is extremely rare. We treated a 1-day-old male neonate who presented with stridor and feeding difficulty and was subsequently diagnosed with NB of the retropharynx. The tumor was excised in toto transorally, and no metastatic lesions were confirmed. Histopathology and molecular genetic analysis showed poorly differentiated NB with no N-myc amplification, stage I NB. He has had no signs of recurrence or adverse sequelae during 18 months of follow-up. We report our experience and review the literature.
Department of Pediatric General and Urogenital Surgery, Juntendo University School of Medicine, 2-1-1 Hongo, Bunkyo-ku, Tokyo, 113-8421, Japan. okazakit@med.juntendo.ac.jp
Tadaharu
T
Okazaki
Masaaki
M
Ohshita
Masayuki
M
Furukawa
Katsuhisa
K
Ikeda
Yutaka
Y
Ozaki
Geoffrey J
GJ
Lane
Atsuyuki
A
Yamataka
D003131:Combined Modality Therapy; D016259:Genes, myc / Q000235:genetics; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D009447:Neuroblastoma / Q000175:diagnosis* / Q000235:genetics / Q000473:pathology / Q000628:therapy; D010610:Pharyngeal Neoplasms / Q000175:diagnosis* / Q000235:genetics / Q000473:pathology / Q000628:therapy