Nutrition: ethics and social implications.
In October 2003, the general conference of UNESCO adopted the International Declaration on Human Genetic Data, followed by the adoption of the Universal Declaration on Bioethics and Human Rights in October 2005 to ensure the respect of human dignity and the protection of human rights and fundamental freedoms in the collection, processing, use and storage of human genetic data with the requirement of equality, justice and solidarity. Nutrigenomics studies the relationship between specific nutrients or diet and polymorphisms and gene expression; therefore, eventually diet can be tailored for each individual. The dietary intervention is based on collected human genetic data that eventually build knowledge of nutritional requirements, and the nutritional status of different human genotypes. This knowledge can be used to prevent, mitigate or cure chronic diseases. As in another branch of posthuman genome science, it is a global concern that the collected data should not be misused or create inequity. Some ethical issues raised and discussed in this paper are: (1) consent and confidentiality issues in the collection and storage of data, (2) genetic screening and how to prevent inequity, (3) regulatory oversight and in a wider context the need to improve public confidence in biotechnology-related science, (4) other social issues. The ethical issues in nutrigenomics need clear and concise guidelines developed in accordance with the universally adopted declarations and ethical concern needs to be integrated in the scientific design. Efforts to improve the public awareness, public participation and consultation need to be made at the early stage of the development of nutrigenomics.
Indonesian Institute of Sciences, National Bioethics Commission, Jakarta, Indonesia.
Inez H
IH
Slamet-Loedin
IUmar A
IA
Jenie
D001675:Bioethics; D015870:Gene Expression; D030661:Genetic Privacy / Q000941:ethics*; D005820:Genetic Testing; D023281:Genomics / Q000941:ethics*; D006806:Human Rights; D006801:Humans; D009747:Nutritional Physiological Phenomena; D009751:Nutritional Requirements; D011110:Polymorphism, Genetic