Direct synthesis of oxazolines from olefins and amides using t-BuOI.
A new and simple method for the synthesis of oxazolines from readily accessible olefins and amides using tert-butyl hypoiodite is described; aromatic/aliphatic olefins and amides can be used in the reaction to give a variety of oxazolines.
Department of Applied Chemistry, Graduate School of Engineering, Osaka University, Yamadaoka 2-1, Suita, Osaka 565-0871, Japan. minakata@chem.eng.osaka-u.ac.jp
Satoshi
S
Minakata
Yoshinobu
Y
Morino
Toshihiro
T
Ide
Yoji
Y
Oderaotoshi
Mitsuo
M
Komatsu
D000475:Alkenes / Q000737:chemistry*; D000577:Amides / Q000737:chemistry*; D007455:Iodine / Q000737:chemistry*; D010080:Oxazoles / Q000138:chemical synthesis*
D000475:Alkenes; D000577:Amides; D010080:Oxazoles; D007455:Iodine