Clinical aspects of haemodiafiltration.
Standard haemodialysis is not a very efficacious treatment of chronic uraemia and patient mortality rate is still very high. The 2002 results of the HEMO study showed that alternative treatments such as 'high-efficiency haemodialysis' and 'high-flux haemodialysis' are associated with a non-significant reduction in the relative risk of mortality (4 and 8%, respectively). In an attempt to define the clinical impact of haemodiafiltration, we review some of the efficacy data from clinical studies in light of a number of factors that may be related to the high mortality among haemodialysis patients.
Department of Nephrology and Dialysis, A. Manzoni Hospital, Lecco, Italy.
Francesco
F
Locatelli
Salvatore
S
Di Filippo
D002318:Cardiovascular Diseases / Q000209:etiology; D017583:Hemodiafiltration / Q000009:adverse effects*; D006801:Humans; D012307:Risk Factors; D015996:Survival Rate; D016896:Treatment Outcome; D014511:Uremia / Q000150:complications / Q000453:epidemiology / Q000628:therapy