BLISS 2.0: a web-based tool for predicting conserved regulatory modules in distantly-related orthologous sequences.
BLISS 2.0 is a web-based application for identifying conserved regulatory modules in distantly related orthologous sequences. Unlike existing approaches, it performs the cross-genome comparison at the binding site level. Experimental results on simulated and real world data indicate that BLISS 2.0 can identify conserved regulatory modules from sequences with little overall similarity at the DNA sequence level.


BACKGROUND
http://www.blisstool.org/
Department of Computer and Information Science, College of Engineering, UFL, Gainesville, FL 32611, USA.
Hailong
H
Meng
Arunava
A
Banerjee
Lei
L
Zhou
D000465:Algorithms; D001483:Base Sequence; D001665:Binding Sites; D017124:Conserved Sequence / Q000235:genetics*; D019143:Evolution, Molecular; D020407:Internet; D008969:Molecular Sequence Data; D011485:Protein Binding; D050436:Regulatory Elements, Transcriptional / Q000235:genetics*; D016415:Sequence Alignment / Q000379:methods; D017422:Sequence Analysis, DNA / Q000379:methods*; D012984:Software; D014157:Transcription Factors / Q000235:genetics*
D014157:Transcription Factors