Detection and characterization of international community-acquired infections by methicillin-resistant Staphylococcus aureus clones in Rio de Janeiro and Porto Alegre cities causing both community- and hospital-associated diseases.
Community-acquired infections by methicillin-resistant Staphylococcus aureus (CA-MRSA) in the absence of classic risk factors for MRSA diseases have been reported in different continents. In the article presented here, using molecular typing methods as pulsed-field gel electrophoresis, staphylococcal cassette chromosome mec typing, and multilocus sequence typing, we characterized CA-MRSA isolates from Rio Janeiro and Porto Alegre. The results indicated the presence of international CA-MRSA clones in these 2 Brazilian cities. In addition, Panton-Valentine leukocidin and a number of staphylococcal enterotoxin encoding genes were accessed in these MRSA isolates by polymerase chain reaction detection.
Instituto de Microbiologia Prof. Paulo de Góes, Centro de Ciências da Saúde (CCS), Universidade Federal do Rio de Janeiro, Cidade Universitária, Rio de Janeiro, RJ 21941-902, Brazil.
Apoena
A
Ribeiro
Amada Zambrana
AZ
Coronado
Maria Cícera
MC
Silva-Carvalho
Bernadete Teixeira
BT
Ferreira-Carvalho
Cícero
C
Dias
Ronaldo
R
Rozenbaum
Pedro Fernandez
PF
Del Peloso
Cassiana
C
da Costa Ferreira Leite
Lenise Arneiro
LA
Teixeira
Agnes Marie Sá
AM
Figueiredo
D001427:Bacterial Toxins / Q000235:genetics; D001938:Brazil / Q000453:epidemiology; D017714:Community-Acquired Infections / Q000453:epidemiology / Q000235:genetics / Q000382:microbiology; D024901:Drug Resistance, Multiple, Bacterial / Q000235:genetics; D016521:Electrophoresis, Gel, Pulsed-Field; D005098:Exotoxins / Q000235:genetics; D005838:Genotype; D006801:Humans; D007956:Leukocidins / Q000235:genetics; D016106:Methicillin Resistance / Q000235:genetics*; D016133:Polymerase Chain Reaction; D013203:Staphylococcal Infections / Q000145:classification / Q000453:epidemiology* / Q000235:genetics; D013211:Staphylococcus aureus / Q000187:drug effects / Q000235:genetics / Q000302:isolation & purification*
D001427:Bacterial Toxins; D005098:Exotoxins; D007956:Leukocidins; C078284:Panton-Valentine leukocidin