Relative contribution of ovarian stimulation versus in vitro fertilization and intracytoplasmic sperm injection to multifetal pregnancies requiring reduction to twins.
The proportion of twins resulting from multifetal pregnancy reduction of higher-order multiples is increased in pregnancies resulting from hormone stimulation when compared with twins following in vitro fertilization/intracytoplasmic sperm injection treatment. These reduced twin pregnancies may carry a higher perinatal risk compared with other twin pregnancies, which should be taken into account when assessing the perinatal outcome of twin pregnancies after assisted reproduction.
Genk Institute for Fertility Technology, Department of Obstetrics and Gynaecology, Genk, Belgium. willem.ombelet@telenet.be
Willem
W
Ombelet
Michel
M
Camus
Luc
L
de Catte
D001530:Belgium / Q000453:epidemiology; D005260:Female; D005307:Fertilization in Vitro / Q000009:adverse effects*; D006801:Humans; D007230:Infant, Low Birth Weight; D007231:Infant, Newborn; D010062:Ovulation Induction / Q000009:adverse effects*; D011247:Pregnancy; D011256:Pregnancy Outcome; D018607:Pregnancy Reduction, Multifetal; D011272:Pregnancy, Multiple; D047928:Premature Birth / Q000453:epidemiology; D020554:Sperm Injections, Intracytoplasmic / Q000009:adverse effects*; D014427:Twins