[A case of small cell carcinoma of the esophagus with remarkable response to chemotherapy with CPT-11 and CDDP].
A 63-year-old man visited our hospital with complaints of the chest pain and loss of appetite. A computed tomography of chest showed wall thickening in the lower portion of the esophagus and carinal and para-aorta lymph node swelling. Upper gastrointestinal endoscopy revealed an irregular ulcerated lesion in the middle portion of the esophagus, which was pathologically diagnosed as small cell carcinoma. A computed tomography of the abdomen showed multiple liver metastases and para-aortic, cardiac, and common hepatic arterial lymph node swelling. One course of combined chemotherapy with CPT-11 and CDDP, then 3 courses of chemotherapy with CPT-11 showed clinical complete remission.
Fourth Department of Internal Medicine, Teikyo University Mizonokuchi Hospital.
Toshihiro
T
Goto
Hirotsugu
H
Watabe
Takayuki
T
Kawakami
Masashi
M
Watanabe
Kentaro
K
Nakano
Atsuko
A
Takai
Eriko
E
Kitazawa
Shinpei
S
Sato
Yasuo
Y
Tajima
Kunio
K
Mizuguchi
Kentaro
K
Kikuchi
Hiroshi
H
Miyakawa
Yuji
Y
Murakawa
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D002166:Camptothecin / Q000008:administration & dosage / Q000031:analogs & derivatives; D018288:Carcinoma, Small Cell / Q000188:drug therapy* / Q000556:secondary; D002945:Cisplatin / Q000008:administration & dosage; D004334:Drug Administration Schedule; D004938:Esophageal Neoplasms / Q000188:drug therapy* / Q000473:pathology; D006801:Humans; D000077146:Irinotecan; D008113:Liver Neoplasms / Q000556:secondary; D008198:Lymph Nodes / Q000473:pathology*; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D012074:Remission Induction
D000077146:Irinotecan; D002945:Cisplatin; D002166:Camptothecin