Parity and disparity in first course treatment of invasive breast cancer.
BACKGROUND
Adherence to first course treatment guidelines for breast cancer may not be uniform across racial/ethnic groups and could be a major contributing factor to disparities in outcome. In this population-based study, we assessed racial differences in initial treatment of breast cancer.


METHODS
Surveillance, Epidemiology, and End Results (SEER) program data were used to study all primary invasive breast cancers diagnosed during 2000-2001 among Black (n = 877) and White (n = 2437) female residents of the five Atlanta SEER counties, counties with several large teaching hospitals. Differences in treatment delay, cancer directed surgery, and receipt of chemotherapy, radiotherapy, or hormonal therapy were analyzed according to guidelines for treatment. Analyses utilized frequency distributions, chi(2) tests of independence and statistics in and across strata.


RESULTS
Black women experienced longer treatment delays, regardless of stage at diagnosis, and were 4-5 fold more likely to experience delays greater than 60 days (P < 0.001). For local-regional disease, more Black women did not receive cancer directed surgery (7.5% vs. 1.5% of white women, P < 0.001), but did receive breast conserving surgery (BCS) equivalently. Only 61% of Black vs. 72% of White women received radiation with BCS (P < 0.001). Black women eligible for hormonal therapy were less likely to receive it (P < 0.001).


CONCLUSIONS
Our findings suggest treatment standards are not adequately or equivalently met among Black and White women, even in an area where teaching hospitals provide a substantial portion of breast cancer care. Treatment differences can adversely affect outcome and reasons for the differences need to be addressed.
Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, 30322, USA. mlund@sph.emory.edu
Mary Jo
MJ
Lund
Otis P
OP
Brawley
Kevin C
KC
Ward
John L
JL
Young
Sheryl S G
SS
Gabram
J William
JW
Eley
D000293:Adolescent; D000328:Adult; D000368:Aged; D044383:Black People; D001943:Breast Neoplasms / Q000737:chemistry / Q000208:ethnology* / Q000628:therapy*; D005260:Female; D006801:Humans; D008875:Middle Aged; D011960:Receptors, Estrogen / Q000032:analysis; D011980:Receptors, Progesterone / Q000032:analysis; D018426:SEER Program; D044465:White People
D011960:Receptors, Estrogen; D011980:Receptors, Progesterone