Choreographing the fly's danse macabre.
In several species, immune signaling networks are emerging as critical modulators of disease resistance, energy metabolism, and aging. In this issue of Cell Metabolism, Ren et al. (2007) lay the groundwork for dissecting the mechanisms of this coordination by characterizing the interplay between microbial pathogens and aging in the fly.
Poon
Peter C
PC
Huffington Center on Aging, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA.
Pletcher
Scott D
SD
D000375:Aging / Q000502:physiology; D000818:Animals; D023181:Antimicrobial Cationic Peptides / Q000235:genetics; D001419:Bacteria; D004331:Drosophila melanogaster / Q000235:genetics / Q000382:microbiology* / Q000648:ultrastructure; D005786:Gene Expression Regulation; D013045:Species Specificity
D023181:Antimicrobial Cationic Peptides