[Cytology and immunophenotype feautures of 80 acute myeloid leukemia].
Acute myeloid leukemia (AML)'s diagnosis is clinical and biological. We report here 80 AML with cytology and immunophenotype features to establish correlations. 21 AML1, 23 AML2, 12 AML3, 2 AML4, 18 AML5 and 3 AML6 were diagnosed by cytology. Only one case of AML0 was diagnosed by immunophenotype. Myelogysplasia is present in 29.8% cases. CD19 and CD56 expression was significantly associated to AML +t(8;21). Additionally, concomitant negativity of CD34 and HLA-DR was discrimininatif to AML3 diagnosis. Prognostic value to expression some CD needs time backwards.
Service d'Hématologie Biologique, l'Hopital Aziza Othmana, Tunis.
Emna
E
Gouider
Sameh
S
Ayari
Selma
S
Bouhoula
Hela
H
Ben Abid
Zaher Belhadj
ZB
Ali
Balkis
B
Meddeb
Aïcha
A
Hafsia
Raouf
R
Hafsia
D000293:Adolescent; D000328:Adult; D018941:Antigens, CD19 / Q000032:analysis; D018952:Antigens, CD34 / Q000032:analysis; D001402:B-Lymphocytes / Q000473:pathology; D019002:CD56 Antigen / Q000032:analysis; D002648:Child; D002675:Child, Preschool; D005260:Female; D006684:HLA-DR Antigens / Q000032:analysis; D006801:Humans; D007150:Immunohistochemistry; D016130:Immunophenotyping; D015470:Leukemia, Myeloid, Acute / Q000145:classification / Q000276:immunology / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009190:Myelodysplastic Syndromes / Q000276:immunology / Q000473:pathology; D022423:Myeloid Cells / Q000473:pathology; D009195:Peroxidase / Q000032:analysis; D011379:Prognosis; D013601:T-Lymphocytes / Q000473:pathology
D018941:Antigens, CD19; D018952:Antigens, CD34; D019002:CD56 Antigen; D006684:HLA-DR Antigens; D009195:Peroxidase