Crystal structure of a biosynthetic sulfo-hirudin complexed to thrombin.
Department of Chemistry and the Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, USA.
Chang C
CC
Liu
Eric
E
Brustad
Wenshe
W
Liu
Peter G
PG
Schultz
D018360:Crystallography, X-Ray; D006629:Hirudins / Q000737:chemistry*; D008958:Models, Molecular; D011487:Protein Conformation; D013917:Thrombin / Q000037:antagonists & inhibitors / Q000737:chemistry*; D014443:Tyrosine / Q000031:analogs & derivatives* / Q000737:chemistry
D006629:Hirudins; C005662:tyrosine O-sulfate; D014443:Tyrosine; D013917:Thrombin