PEEK biomaterials in trauma, orthopedic, and spinal implants.
Since the 1980s, polyaryletherketones (PAEKs) have been increasingly employed as biomaterials for trauma, orthopedic, and spinal implants. We have synthesized the extensive polymer science literature as it relates to structure, mechanical properties, and chemical resistance of PAEK biomaterials. With this foundation, one can more readily appreciate why this family of polymers will be inherently strong, inert, and biocompatible. Due to its relative inertness, PEEK biomaterials are an attractive platform upon which to develop novel bioactive materials, and some steps have already been taken in that direction, with the blending of HA and TCP into sintered PEEK. However, to date, blended HA-PEEK composites have involved a trade-off in mechanical properties in exchange for their increased bioactivity. PEEK has had the greatest clinical impact in the field of spine implant design, and PEEK is now broadly accepted as a radiolucent alternative to metallic biomaterials in the spine community. For mature fields, such as total joint replacements and fracture fixation implants, radiolucency is an attractive but not necessarily critical material feature.
Kurtz
Steven M
SM
Exponent, Inc., 3401 Market Street, Suite 300, Philadelphia, PA 19104, USA. skurtz@exponent.com
Devine
John N
JN
D001577:Benzophenones; D001672:Biocompatible Materials / Q000737:chemistry*; D006801:Humans; D007659:Ketones / Q000737:chemistry*; D011092:Polyethylene Glycols / Q000737:chemistry*; D011108:Polymers; D019736:Prostheses and Implants; D013119:Spinal Cord Injuries / Q000628:therapy; D014947:Wounds and Injuries / Q000628:therapy*
D001577:Benzophenones; D001672:Biocompatible Materials; D007659:Ketones; D011108:Polymers; C063834:polyetheretherketone; D011092:Polyethylene Glycols