Schwannoma of the breast: a case report and review of the literature.
Schwannoma arising within breast parenchyma is very rare. This report describes such a case in a 58-year-old woman. The tumor, which measured 4.4 x 3.5 x 2.1 cm, was painless, mobile and elastic-soft. Mammography showed a well-circumscribed, oval-shaped nodule without microcalcifications. At ultrasonography it appeared as a hypoechoic solid mass. Fine-needle cytology revealed several clusters of spindle cells indicative of a neoplasm of mesenchymal origin. Histological examination evidenced the characteristic morphological appearance of a schwannoma with Antoni A and Antoni B areas. A review of the 23 proven cases of breast schwannoma is included. The main differential diagnostic findings are also discussed.
Bellezza
Guido
G
Institute of Pathologic Anatomy and Histology, Division of Cancer Research, Perugia Medical School, University of Perugia, Perugia, Italy. guidobellezza@virgilio.it
Lombardi
Tiziana
T
Panzarola
Paola
P
Sidoni
Angelo
A
Cavaliere
Antonio
A
Giansanti
Michele
M
D044963:Biopsy, Fine-Needle; D001943:Breast Neoplasms / Q000737:chemistry / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D002277:Carcinoma / Q000175:diagnosis; D003893:Desmin / Q000032:analysis; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008875:Middle Aged; D009363:Neoplasm Proteins / Q000032:analysis; D009442:Neurilemmoma / Q000737:chemistry / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D009418:S100 Proteins / Q000032:analysis; D014463:Ultrasonography
D003893:Desmin; D009363:Neoplasm Proteins; D009418:S100 Proteins