Design and development of a flow injection-capillary electrophoresis analyzer employing fiber optic detection.
The development and experimental optimization of a novel flow injection-capillary electrophoresis (FI-CE) analyzer employing UV-visible fiber optic detection is described. The analyzer incorporates a miniature charge-coupled device (CCD) spectrometer and operates in a graphical programming environment. Data from experimental optimization studies and small molecule separations involving affinity capillary electrophoresis (ACE) and indirect detection of anions are presented. Future directions in terms of instrument automation and incorporation into a microfluidic format are also discussed.
Hanrahan
Grady
G
Department of Chemistry & Biochemistry, California State University, Los Angeles, CA 90032, USA. ghanrah@calstatela.edu
Tse
Florence
F
Dahdouh
Froseen T
FT
Clarke
Keith
K
Gomez
Frank A
FA
D019075:Electrophoresis, Capillary / Q000295:instrumentation* / Q000379:methods*; D005336:Fiber Optic Technology / Q000295:instrumentation* / Q000379:methods*; D017022:Flow Injection Analysis; D005998:Glycine; D055100:Optical Fibers; D014640:Vancomycin
D014640:Vancomycin; D005998:Glycine