[Renal and urinary tract disease national research program].
The National Institute of Health and Medical Research (Inserm), the Society of Nephrology, and the French Kidney Foundation recognized the need to create a National Research Program for kidney and urinary tract diseases. They organized a conference gathering 80 researchers to discuss the state-of-the art and evaluate the strengths and weaknesses of kidney and urinary tract disease research in France, and to identify research priorities. From these priorities emerged 11 of common interest: 1) conducting epidemiologic studies; 2) conducting large multicenter cohorts of well-phenotyped patients with blood, urine and biopsy biobanks; 3) developing large scale approach: transcriptomics, proteomics, metabolomics; 4) developing human and animal functional imaging techniques; 5) strengthening the expertise in renal pathology and electrophysiology; 6) developing animal models of kidney injury; 7) identifying nontraumatic diagnostic and prognostic biomarkers; 8) increasing research on the fetal programming of adult kidney diseases; 9) encouraging translational research from bench to bedside and to population; 10) creating centers grouping basic and clinical research workforces with critical mass and adequate logistic support; 11) integrating and developing european research programs.
Stengel
Bénédicte
B
Inserm U780, 16, avenue Paul-Vaillant-Couturier, 94807 Villejuif cedex, France. stengel@vjf.inserm.fr
Antignac
Corinne
C
Baverel
Gabriel
G
Choukroun
Gabriel
G
Cussenot
Olivier
O
Dussaule
Jean-Claude
JC
Friedlander
Gérard
G
Lang
Philippe
P
Lelièvre-Pégorier
Martine
M
Massy
Ziad
Z
Monteiro
Renato
R
Parini
Angelo
A
Soulillou
Jean Paul
JP
Baud
Laurent
L
Ronco
Pierre
P
D005582:Foundations; D005602:France / Q000453:epidemiology; D006801:Humans; D015994:Incidence; D007674:Kidney Diseases / Q000145:classification / Q000453:epidemiology; D016030:Kidney Transplantation / Q000706:statistics & numerical data; D012106:Research / Q000639:trends*; D014570:Urologic Diseases / Q000145:classification / Q000453:epidemiology