EBV-associated diseases in the AIDS patient.
EBV-associated malignancies remain a considerable problem in HIV-infected individuals, even in the era of HAART. Although EBV is a common factor, each disease has a unique pathogenesis. Study of these diseases reveals the viral proteins expressed in the malignancies that might contribute to the development of the disease as well as the molecular basis for pathogenesis. It is likely that this knowledge will contribute to the development of novel therapeutics that will result in more favorable outcomes in the future.
Department of Biochemistry, St.Jude Children's Research Hospital, Memphis, TN, USA.
Scott M
SM
Long
Clare E
CE
Sample
D000163:Acquired Immunodeficiency Syndrome / Q000150:complications*; D020031:Epstein-Barr Virus Infections / Q000150:complications*; D004854:Herpesvirus 4, Human / Q000235:genetics / Q000302:isolation & purification / Q000502:physiology*; D006801:Humans; D009369:Neoplasms / Q000473:pathology / Q000821:virology; D017735:Virus Latency