Amniotic membrane grafting for conjunctival and lid surface disease in the acute phase of toxic epidermal necrolysis.
Toxic epidermal necrolysis (TEN) is a severe form of Stevens-Johnson syndrome, characterized by extensive sloughing of mucous membranes and skin. It is associated with mortality rates of up to 70% and significant ocular morbidity in long-term survivors. We present a case of TEN with severe bilateral ocular involvement in whom we successfully used amniotic membrane grafts to treat the ocular surface during the acute phase of the disease.
Princess Alexandra Eye Pavilion, Edinburgh, Scotland, UK.
Anamika
A
Tandon
Peter
P
Cackett
Alan
A
Mulvihill
Brian
B
Fleck
D000208:Acute Disease; D000650:Amnion / Q000637:transplantation*; D002648:Child; D003229:Conjunctival Diseases / Q000601:surgery*; D005141:Eyelid Diseases / Q000601:surgery*; D005260:Female; D006801:Humans; D013262:Stevens-Johnson Syndrome / Q000601:surgery*