[Influence of excipients on moisture absorption and dispersibility of Shuanghuanglian microcapsules].
OBJECTIVE
To study the influences of excipients on the moisture absorption and dispersibility of Shuanghuanglian microcapsules.


METHODS
Shuanghuanglian microcapsules were prepared with different wall materials, antisticking agents and ratio of medicinal materials to exipients, and the moisture absorption and dispersibility of the microcapsules were determined.


RESULTS
The dispersibility of Shuanghuanglian microcapsules weakened with the increasing of moisture absorption, but some samples were of good dispersibility in spite of the high moisture absorption.


CONCLUSIONS
During the research on the dampproof technologies, not only the moisture absorption, but also the dispersibility of samples should be investigated.
Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China. liuwalter@sohu.com
Yi
Y
Liu
De-sheng
DS
Xu
Yi
Y
Feng
Lan
L
Shen
D002214:Capsules; D002482:Cellulose / Q000737:chemistry; D002626:Chemistry, Pharmaceutical; D004355:Drug Stability; D004365:Drugs, Chinese Herbal / Q000737:chemistry*; D005079:Excipients / Q000737:chemistry*; D006813:Humidity; D010316:Particle Size; D011208:Powders; D013229:Stearic Acids / Q000737:chemistry; D013678:Technology, Pharmaceutical / Q000379:methods; D014783:Viscosity; D014867:Water / Q000737:chemistry*; D017155:Wettability
D002214:Capsules; D004365:Drugs, Chinese Herbal; D005079:Excipients; D011208:Powders; D013229:Stearic Acids; C516400:shuang-huang-lian; D014867:Water; D002482:Cellulose