The value of routine preoperative electrocardiography in predicting myocardial infarction after noncardiac surgery.
OBJECTIVE
The added value of a preoperative electrocardiogram (ECG) in the prediction of postoperative myocardial infarction (POMI) and death was compared with clinical risk factors identified from the patient's history.


BACKGROUND
An ECG is frequently performed before surgery to screen for asymptomatic coronary artery disease. However, the value of ECG abnormalities to predict POMI has been questioned.


METHODS
The study included 2967 noncardiac surgery patients >50 years of age from 2 university hospitals, who were expected to stay in the hospital for >24 hours. All data were obtained from electronic record-keeping systems. Patient history and ECG abnormalities were considered as potential predictors. Multivariate logistic regression analysis was used to obtain the independent predictors of POMI and all-cause in-hospital mortality. The area under the receiver operating characteristic curve (ROC area) was estimated to evaluate the ability of different models to discriminate between patients with and without the outcome.


RESULTS
A preoperative ECG was available in 2422 patients (80%) and 1087 (45%) of the ECGs showed at least one abnormality. The ROC area of the model that included the independent predictors of POMI obtained from patient history, ie, ischemic heart disease and high-risk surgery, was 0.80. ECG abnormalities that were associated with POMI were a right and a left bundle branch block. After adding these abnormalities in the regression model, the ROC area remained 0.80. Similar results were found for all-cause mortality.


CONCLUSIONS
Bundle branch blocks identified on the preoperative ECG were related to POMI and death but did not improve prediction beyond risk factors identified on patient history.
University Medical Center Utrecht, Dept Perioperative Care and Emergency Medicine, Utrecht, The Netherlands. w.a.vanklei@umcutrecht.nl
Wilton A
WA
van Klei
Gregory L
GL
Bryson
Homer
H
Yang
Cor J
CJ
Kalkman
George A
GA
Wells
W Scott
WS
Beattie
D000367:Age Factors; D000368:Aged; D004562:Electrocardiography; D005260:Female; D005500:Follow-Up Studies; D017052:Hospital Mortality; D006801:Humans; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D009203:Myocardial Infarction / Q000175:diagnosis* / Q000209:etiology / Q000401:mortality; D009426:Netherlands / Q000453:epidemiology; D009864:Ontario / Q000453:epidemiology; D011183:Postoperative Complications; D011237:Predictive Value of Tests; D011379:Prognosis; D011446:Prospective Studies; D012307:Risk Factors; D012737:Sex Factors; D013514:Surgical Procedures, Operative / Q000009:adverse effects*; D015996:Survival Rate