Optic disc size in a population-based study in central India: the Central India Eye and Medical Study (CIEMS).
OBJECTIVE
To determine optic disc size and its associations in an adult population in central India.


METHODS
The Central India Eye and Medical Study (CIEMS), Part 1 is a population-based, cross-sectional cohort study and included 1000 subjects out of 1314 (76.1%) subjects from a rural area of Maharasthra/India, aged 30+ years, invited to participate. Confocal laser scanning tomographic optic disc images were morphometrically examined.


RESULTS
Mean optic disc area (2.25 +/- 0.51 mm2, range 1.12-4.61 mm2) was significantly correlated with myopic refractive error (p < 0.001) and axial length (p < 0.001), whereas gender (p = 0.14), body height (p = 0.44) and best corrected visual acuity (p = 0.59) were not significantly associated in multiple regression analysis.


CONCLUSIONS
Mean optic disc area is larger in the central Indian population than in White people. Axial length and myopic refractive error are independent factors that influence optic disc size.
Nangia
Vinay
V
Suraj Eye Institute, Nagpur, Maharashtra, India.
Matin
Arshia
A
Bhojwani
Krishna
K
Kulkarni
Maithili
M
Yadav
Monica
M
Jonas
Jost B
JB
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D044466:Asian People; D015331:Cohort Studies; D003430:Cross-Sectional Studies; D006801:Humans; D007194:India; D018613:Microscopy, Confocal; D008875:Middle Aged; D009216:Myopia / Q000473:pathology* / Q000503:physiopathology*; D009898:Optic Disk / Q000033:anatomy & histology* / Q000473:pathology*; D009929:Organ Size; D012029:Refraction, Ocular