[Liver resection after downstaging with systemic chemotherapy in a case of a multicentric hepatocellular carcinoma with virus B cirrhosis].
Hepatocellular carcinoma is often diagnosed in an advanced stage when curative therapeutical options are limited, especially with coexisted cirrhosis. Downstaging-resection plays a role in improving prognosis of unresectable hepatocarcinoma. We report the case of a 27 years old woman with multicentric hepatocellular carcinoma and virus B cirrhosis, portal vein thrombosis with systemic chemotherapy followed be hepatic resection--left hepatectomy and lymph node dissection for the remaining tumor. Postoperative outcome was uneventful, the patient being alive at 22 month after diagnosis, without recurrence. Combined modalities with systemic chemotherapy and surgical resection can achieve complete clinical remission and long-term control of disease in patients with unresectable hepatocarcinoma.
Centrul de Chirurgie generală şi Transplant Hepatic, Institutul Clinic Fundeni Sos. Fundeni 258, sector 2, 022328, Bucureşti.
M
M
Ionescu
T
T
Dumitraşcu
C
C
Stroescu
D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D006528:Carcinoma, Hepatocellular / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery* / Q000821:virology; D005260:Female; D006498:Hepatectomy; D019694:Hepatitis B, Chronic / Q000150:complications / Q000175:diagnosis*; D006801:Humans; D008103:Liver Cirrhosis / Q000150:complications / Q000175:diagnosis*; D008113:Liver Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery* / Q000821:virology; D009367:Neoplasm Staging; D016896:Treatment Outcome