Chronic granulomatous disease associated with atypical Kawasaki disease.
Chronic granulomatous disease (CGD) is an infrequent inherited disorder characterized by recurrent infections and abnormal granuloma formation. Patients with CGD have an exuberant inflammatory response and an increased risk of developing autoimmunity. We present the case of a 1-year-old boy with CGD who developed several of the characteristic clinical features of Kawasaki Disease. His illness responded to intravenous immunoglobulin, aspirin, and corticosteroids.
Department of Clinical Immunology, Instituto Nacional de Pediatría, Insurgentes Sur 3700-C C.P, 04530, Col. Insurgentes Cuicuilco, Mexico City, Mexico. yzki71@yahoo.com.mx
M A
MA
Yamazaki-Nakashimada
N
N
Ramírez-Vargas
J
J
De Rubens-Figueroa
D015897:Comorbidity; D004359:Drug Therapy, Combination; D005938:Glucocorticoids / Q000627:therapeutic use; D006105:Granulomatous Disease, Chronic / Q000188:drug therapy / Q000453:epidemiology*; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use; D007155:Immunologic Factors / Q000627:therapeutic use*; D007223:Infant; D008297:Male; D009080:Mucocutaneous Lymph Node Syndrome / Q000188:drug therapy / Q000453:epidemiology* / Q000209:etiology; D011239:Prednisolone / Q000627:therapeutic use
D005938:Glucocorticoids; D016756:Immunoglobulins, Intravenous; D007155:Immunologic Factors; D011239:Prednisolone