Target-controlled infusion of propofol combined with variable rate infusion of remifentanil for anaesthesia of a dog with patent ductus arteriosus.
An 18-month-old Lurcher was anaesthetized for surgical ligation of a patent ductus arteriosus using a target-controlled infusion (TCI) of propofol and a variable rate infusion of remifentanil. Before anaesthesia, radiographic and echocardiographic examination indicated that the dog had left-sided congestive heart failure and impaired left ventricular systolic function. Ramipril and furosemide were administered pre-operatively. Following pre-anaesthetic medication with morphine, 0.5 mg kg(-1), by intramuscular injection, and pre-oxygenation, remifentanil was infused for 5 minutes at 0.2 microg kg(-1) minute(-1), followed by induction of anaesthesia using intravenous propofol administered by TCI, set at a target concentration of 3.5 microg mL(-1) of propofol in blood. Tracheal intubation was performed and 100% oxygen delivered through a non-rebreathing (Bain) system and then a circle system in the operating theatre. Anaesthesia was maintained with propofol and remifentanil, adjusted according to clinical requirements. Peri-operative analgesia consisted of intercostal bupivacaine nerve block, with meloxicam, morphine and remifentanil.
Division of Companion Animal Science, Institute of Comparative Medicine, University of Glasgow Veterinary School, Glasgow, UK. gmusk@murdoch.edu.au
Gabrielle C
GC
Musk
Derek A
DA
Flaherty
D000758:Anesthesia / Q000662:veterinary*; D019162:Anesthetics, Combined / Q000008:administration & dosage*; D018686:Anesthetics, Intravenous / Q000008:administration & dosage*; D000818:Animals; D004283:Dog Diseases / Q000503:physiopathology*; D004285:Dogs / Q000502:physiology*; D004374:Ductus Arteriosus, Patent / Q000503:physiopathology*; D005260:Female; D007262:Infusions, Intravenous / Q000662:veterinary; D010880:Piperidines / Q000008:administration & dosage*; D015742:Propofol / Q000008:administration & dosage*; D000077208:Remifentanil
D019162:Anesthetics, Combined; D018686:Anesthetics, Intravenous; D010880:Piperidines; D000077208:Remifentanil; D015742:Propofol