Leishmania major infection in a patient with visceral leishmaniasis: treatment with Amphotericin B.
We have reported an acute form of visceral leishmaniasis, which was caused by Leishmania major, in Southern Iran. The parasite was isolated from a 30-year-old man living in Bushehr Province, Southern Iran, and an endemic region of kala-azar in south of Iran. The patient had typical clinical signs of Mediterranean kala-azar, and besides parasitological, biochemical, and immunological findings confirming diagnosis of visceral leishmaniasis, the agent was identified as L. major using Nested polymerase chain reaction. The patient was treated successfully with Amphotericin B during a 1-month period.
Karamian
Mehdi
M
Department of Parasitology and Mycology, School of Medicine, Shiraz University of Medical Sciences, P.O. Box 71345-1744, Shiraz, Iran.
Motazedian
Mohammad Hossein
MH
Mehrabani
Davood
D
Gholami
Khodakaram
K
D000328:Adult; D000666:Amphotericin B / Q000627:therapeutic use*; D000818:Animals; D016054:DNA, Protozoan / Q000235:genetics; D006801:Humans; D007492:Iran; D018320:Leishmania major / Q000235:genetics / Q000302:isolation & purification*; D007898:Leishmaniasis, Visceral / Q000188:drug therapy* / Q000469:parasitology*; D008297:Male; D016133:Polymerase Chain Reaction / Q000379:methods
D016054:DNA, Protozoan; D000666:Amphotericin B