Prevalence of dementia in intellectual disability using different diagnostic criteria.
BACKGROUND
Diagnosis of dementia is complex in adults with intellectual disability owing to their pre-existing deficits and different presentation.


OBJECTIVE
To describe the clinical features and prevalence of dementia and its subtypes, and to compare the concurrent validity of dementia criteria in older adults with intellectual disability.


METHODS
The Becoming Older with Learning Disability (BOLD) memory study is a two-stage epidemiological survey of adults with intellectual disability without Down syndrome aged 60 years and older, with comprehensive assessment of people who screen positive. Dementia was diagnosed according to ICD-10, DSM-IV and DC-LD criteria.


RESULTS
The DSM-IV dementia criteria were more inclusive. Diagnosis using ICD-10 excluded people with even moderate dementia. Clinical subtypes of dementia can be recognised in adults with intellectual disability. Alzheimer's dementia was the most common, with a prevalence of 8.6% (95% CI 5.2-13.0), almost three times greater than expected.


CONCLUSIONS
Dementia is common in older adults with intellectual disability, but prevalence differs according to the diagnostic criteria used. This has implications for clinical practice.
Department of Mental Health Sciences, Royal Free and University College Medical School, UCL Hampstead Campus, London NW3 2PF, UK. a.strydom@medsch.ucl.ac.uk
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Strydom
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Livingston
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King
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Hassiotis
D000368:Aged; D003704:Dementia / Q000175:diagnosis / Q000453:epidemiology* / Q000523:psychology; D005260:Female; D006801:Humans; D008607:Intellectual Disability / Q000523:psychology*; D007859:Learning Disabilities / Q000523:psychology*; D008131:London / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D011569:Psychiatric Status Rating Scales / Q000706:statistics & numerical data