Strategies to reduce clinical inertia in hypertensive kidney transplant recipients.
BACKGROUND
Many kidney transplant recipients have hypertension. Elevated systolic blood pressures are associated with lower patient and kidney allograft survival.


METHODS
This retrospective analysis examined the prevalence of clinical inertia (failure to initiate or increase therapy) in the treatment of hypertension before and after the introduction of an automated device (BpTRU) in the kidney transplant clinic.


RESULTS
Historically only 36% (49/134) of patients were prescribed a change in therapy despite a systolic blood pressure > or = 130 mmHg. After the introduction of BpTRU, 56% (62/110) of the patients had a change in therapy. In a multivariate logistic regression analysis of the entire cohort (n = 244) therapeutic changes were associated with higher blood pressures (OR 1.08 per mmHg, 95% CI 1.04-1.12) and use of the BpTRU (OR 2.12, 95% CI 1.72-3.83). In addition patients on more medications were also more likely to have a change in therapy.


CONCLUSIONS
Blood pressure measurement with automated devices may help reduce clinical inertia in the kidney transplant clinic.
Kiberd
James
J
Department of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada. bryce.kiberd@dal.ca
Panek
Romauld
R
Kiberd
Bryce
B
D000328:Adult; D000368:Aged; D000959:Antihypertensive Agents / Q000627:therapeutic use; D001794:Blood Pressure / Q000187:drug effects / Q000502:physiology; D018660:Blood Pressure Monitoring, Ambulatory / Q000379:methods; D015331:Cohort Studies; D005260:Female; D006801:Humans; D006973:Hypertension / Q000175:diagnosis* / Q000503:physiopathology / Q000628:therapy*; D016030:Kidney Transplantation / Q000009:adverse effects; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012189:Retrospective Studies
D000959:Antihypertensive Agents