Arterial pulse waveform analysis by the probability distribution of amplitude.
Augmentation index (AIx) calculated from the pressure waveform of an artery is widely used to quantify the arterial stiffness and evaluate the cardiovascular risk. The key for calculating AIx is to locate the inflection point on the waveform signal, which is caused by the wave reflection. This study applies the probability distribution of the pressure waveform to identify the inflection point for estimating AIx. The results show that the pulse wave probability analysis not only can estimate AIx with a better tolerance of noise interference, but also allows for simultaneously monitoring, locating and characterizing other physiologically significant points on the pressure waveform.
Tsui
Po-Hsiang
PH
Division of Mechanics, Research Center for Applied Sciences, Academia Sinica, Taipei 11529, Taiwan, Republic of China.
Lin
Lian-Yu
LY
Chang
Chien-Chung
CC
Hwang
Juey-Jen
JJ
Lin
Jen-Jen
JJ
Chu
Chin-Chou
CC
Chen
Chiung-Nien
CN
Chang
King-Jen
KJ
Chang
Chien-Cheng
CC
D000465:Algorithms; D001158:Arteries / Q000502:physiology*; D001696:Biomechanical Phenomena; D002339:Carotid Arteries / Q000502:physiology; D003627:Data Interpretation, Statistical; D006801:Humans; D009131:Muscle, Smooth, Vascular / Q000502:physiology*; D011336:Probability