Haemorrhagic presentation of low-grade glioma in adults.
Intracranial bleeding is rare in patients with low-grade gliomas, above all in adult population. We reviewed the literature of such cases and reported another case of a haemorrhagic low-grade glioma in a 54-year-old woman presenting with a left hemiparesis. Computer tomography (CT) images showed a right basal ganglia haemorrhage with no mass effect. Vascular malformations were ruled out by angiography. Eighteen fluoro-fluoro deossiglucosio (18F-FDG) positron emission tomography (PET/CT) showed a large hypometabolic area corresponding to the lesion. We waited for patient's improvement. Late magnetic resonance images revealed a low-grade glioma at the bleeding site. Tumour was removed and histopathologic examination revealed a WHO grade II mixed glioma. The authors emphasize that this evidence has to be kept in mind since it has important therapeutic implications.
Department of Neurosurgery, Padua Hospital, Padua, Italy. alessandro.dellapuppa@sanita.padova.it
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A
Della Puppa
F
F
Zustovich
M
M
Gardiman
R
R
Manara
D
D
Cecchin
R
R
Scienza
D001254:Astrocytoma / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D001480:Basal Ganglia Diseases / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D020145:Basal Ganglia Hemorrhage / Q000175:diagnosis / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D001932:Brain Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D017024:Chemotherapy, Adjuvant; D003131:Combined Modality Therapy; D003399:Craniotomy; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D038361:Neuronavigation; D049268:Positron-Emission Tomography; D020146:Putaminal Hemorrhage / Q000175:diagnosis / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D014057:Tomography, X-Ray Computed