[Good response in ARDS treated with sivelestat sodium hydrate during chemotherapy for cholangiocarcinoma].
We experienced a case of good response in acute respiratory distress syndrome (ARDS) treated with sivelestat sodium hydrate during chemotherapy for cholangiocarcinoma. A 66-year-old male treated with combined paclitaxel (PTX) and S-1 suffered from ARDS following neutropenia. Sputum and blood culture examinations demonstrated an unknown origin, so sivelestat sodium hydrate was considered more effective than antibiotics. Sivelestat sodium hydrate ought to be used for ARDS treatment even during administration of anti-cancer agent.
Dept. of Surgery, Izumi General Medical Center.
Norihisa
N
Hanada
Shuichi
S
Kusano
Kazuki
K
Hori
Hiroaki
H
Momi
D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects / Q000627:therapeutic use*; D001650:Bile Duct Neoplasms / Q000188:drug therapy*; D001653:Bile Ducts, Intrahepatic; D018281:Cholangiocarcinoma / Q000188:drug therapy*; D004334:Drug Administration Schedule; D004338:Drug Combinations; D005998:Glycine / Q000031:analogs & derivatives* / Q000627:therapeutic use; D006801:Humans; D008297:Male; D009503:Neutropenia / Q000209:etiology; D010094:Oxonic Acid / Q000008:administration & dosage; D017239:Paclitaxel / Q000008:administration & dosage; D012128:Respiratory Distress Syndrome / Q000188:drug therapy* / Q000209:etiology; D015842:Serine Proteinase Inhibitors / Q000627:therapeutic use*; D013449:Sulfonamides / Q000627:therapeutic use*; D005641:Tegafur / Q000008:administration & dosage
D004338:Drug Combinations; D015842:Serine Proteinase Inhibitors; D013449:Sulfonamides; C079198:S 1 (combination); D005641:Tegafur; D010094:Oxonic Acid; C069195:sivelestat; D017239:Paclitaxel; D005998:Glycine