[Recurrent mature ovarian teratomas: retrospective analysis of 20 cases].
OBJECTIVE
To investigate the clinical characteristics and the rule of recurrence of mature ovarian teratoma.


METHODS
The clinical data of 20 patients with recurrent mature ovarian teratoma treated 1965 approximately 2002 was analyzed retrospectively and compared with the data of 40 patients without recurrence who were randomly selected at the ratio of 1 patient with recurrence to 2 patients without recurrence and who underwent surgical treatment in the same operation dates as the corresponding patients with recurrence.


RESULTS
The overall recurrence rate after The patients with recurrence was (26 +/- 7) years old on average at the onset of recurrence, significantly younger than those without recurrence [(30 +/- 6 yearly old, P < 0.05). There were no significant differences in gravidity, parity, and the cyst size, manner of surgery, and rupture during operation between the 2 groups (all P > 0.05). The incidence rates of bilateral or multilocular cysts in the patients with recurrence were significantly higher than those of the patients without recurrence (P < 0.05 or P < 0.01). The overall recurrence rate after conservative treatment was 2.5%. The mean period of recurrence was 8 +/- 7 years.


CONCLUSIONS
Younger patients and patients bilateral or multiple dermoid cysts should be followed up closely. Laparoscopy is the best treatment choice for mature ovarian teratoma. Biopsy of the contralateral ovary is not recommended regularly in surgery.
Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Science, Beijing 100730, China.
Ying-na
YN
Song
Lan
L
Zhu
Jing-he
JH
Lang
D000328:Adult; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D009364:Neoplasm Recurrence, Local; D010051:Ovarian Neoplasms / Q000473:pathology* / Q000601:surgery; D011247:Pregnancy; D011256:Pregnancy Outcome; D018873:Pregnancy Rate; D012189:Retrospective Studies; D013724:Teratoma / Q000473:pathology* / Q000601:surgery