[Stewart's acid-base approach].
In addition to paCO(2), Stewart's acid base model takes into account the influence of albumin, inorganic phosphate, electrolytes and lactate on acid-base equilibrium. It allows a comprehensive and quantitative analysis of acid-base disorders. Particularly simultaneous and mixed metabolic acid-base disorders, which are common in critically ill patients, can be assessed. Stewart's approach is therefore a valuable tool in addition to the customary acid-base approach based on bicarbonate or base excess. However, some chemical aspects of Stewart's approach remain controversial.
Funk
Georg-Christian
GC
Erste Interne Lungenabteilung, Otto Wagner Spital, Vienna, Austria. georg-christian.funk@wienkav.at
D000136:Acid-Base Equilibrium / Q000502:physiology*; D000138:Acidosis / Q000503:physiopathology*; D000471:Alkalosis / Q000503:physiopathology*; D000838:Anions / Q000097:blood; D001639:Bicarbonates / Q000097:blood; D002412:Cations / Q000097:blood; D016883:Diabetic Ketoacidosis / Q000503:physiopathology; D004573:Electrolytes / Q000097:blood; D006801:Humans; D007262:Infusions, Intravenous; D007674:Kidney Diseases / Q000503:physiopathology; D019344:Lactic Acid / Q000097:blood; D008107:Liver Diseases / Q000503:physiopathology; D010710:Phosphates / Q000097:blood; D017582:Renal Replacement Therapy; D012709:Serum Albumin / Q000378:metabolism
D000838:Anions; D001639:Bicarbonates; D002412:Cations; D004573:Electrolytes; D010710:Phosphates; D012709:Serum Albumin; D019344:Lactic Acid