Intracranial meningioma containing metastatic colon carcinoma.
Tumour-to-tumour metastasis is a rare pathological entity. Meningioma is the most common intracranial tumour to host metastases, the majority of which arise from breast and lung cancers. We present the first report of a colonic cancer metastasis within an intracranial meningioma.A 76-year-old woman presented with a one month history of partial seizures. Her medical history included resection of an adenocarcinoma of the descending colon followed by adjuvant chemotherapy 1 year before our evaluation. Magnetic resonance imaging revealed a homogeneously enhancing lesion in the right frontal convexity.A well capsulated tumour attached to the frontal dura was surgically removed. The pathological examination demonstrated a mixture of fibrous meningioma and colloid adenocarcinoma. Possible explanations for the development of a cohesive chimeric mass of composite pathology are investigated.
Neurosurgical Department, University of Florence, Firenze, Italy.
N
N
Benedetto
P
P
Perrini
A
A
Scollato
A M
AM
Buccoliero
N
N
Di Lorenzo
D000230:Adenocarcinoma / Q000175:diagnosis / Q000473:pathology / Q000556:secondary* / Q000601:surgery*; D000368:Aged; D003082:Colectomy; D003110:Colonic Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D003399:Craniotomy; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008577:Meningeal Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000556:secondary* / Q000601:surgery*; D008579:Meningioma / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D016609:Neoplasms, Second Primary / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D011183:Postoperative Complications / Q000175:diagnosis / Q000473:pathology / Q000601:surgery; D012086:Reoperation