[The influence of the increasing doses of vitamin C on the concentration of the substance reacting with thiobarbituric acid (TBARS) in mice liver].
Ascorbic acid is known antioxidant protecting many organs and tissues. In some circumstances can act as prooxidant, particullary when coexists with high concentration of ferrum and copper jons. Condition like that can take place for example in liver. In this research Vitamin C was administered to the mice in increasing dosages, then the concentration of TBARS-prooxidant markers was measured in homogenats of their livers. The outcomes of the research are equivocal.
Oddział Chirurgii Ogólnej Szpitala MSWiA w Łodzi.
Rafał
R
Drozda
Krzysztof
K
Grzegorczyk
Maciej
M
Rutkowski
Krzysztof
K
Kołomecki
D000818:Animals; D000975:Antioxidants / Q000008:administration & dosage* / Q000378:metabolism; D001205:Ascorbic Acid / Q000008:administration & dosage* / Q000378:metabolism; D019587:Dietary Supplements; D004305:Dose-Response Relationship, Drug; D005260:Female; D015227:Lipid Peroxidation / Q000187:drug effects; D008099:Liver / Q000737:chemistry / Q000378:metabolism*; D051379:Mice; D008807:Mice, Inbred BALB C; D010084:Oxidation-Reduction / Q000187:drug effects; D017392:Thiobarbituric Acid Reactive Substances / Q000737:chemistry / Q000378:metabolism*; D014018:Tissue Distribution
D000975:Antioxidants; D017392:Thiobarbituric Acid Reactive Substances; D001205:Ascorbic Acid