[Nadroparin-induced skin necrosis then thrombocytosis in intensive care unit: difficulty in diagnosis].
Skin necrosis is a rare complication in intensive care unit. A case-report of nadroparine-induced skin necrosis and thrombocytosis in a patient with traumatic paraplegia is reported. This case emphasised the difficulty in diagnosis despite absence of thrombopenia. A skin necrosis could suggest the diagnosis and a substitutive therapy must be administrated after heparin therapy withdrawal. A thrombocytosis is a little reported complication of low-molecular-weight heparins without complication.
Service d'anesthésie-réanimation-urgences-Smur, hôpital Beaujon, Assistance publique-Hôpitaux de Paris, Clichy, France. perbetseb@hotmail.com <perbetseb@hotmail.com>
S
S
Perbet
P
P
Trouiller
C
C
Paugam-Burtz
M-H
MH
Denninger
J
J
Mantz
D000328:Adult; D000925:Anticoagulants / Q000009:adverse effects*; D006801:Humans; D007362:Intensive Care Units; D008297:Male; D017762:Nadroparin / Q000009:adverse effects*; D009336:Necrosis; D012867:Skin / Q000473:pathology*; D013922:Thrombocytosis / Q000139:chemically induced* / Q000175:diagnosis*
D000925:Anticoagulants; D017762:Nadroparin