Highly regioselective synthesis of indene derivatives including an allene functional group via Pd/C-catalyzed cyclization reaction in air.
Indene derivatives including an allene functional group are readily prepared in moderate to excellent yields with high regioselectivity under very mild reaction conditions by the Pd/C-catalyzed reaction of propargylic compounds. The resulting products can be further elaborated using Pd-catalyzed annulation reactions.
State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, People's Republic of China.
Hai-Peng
HP
Bi
Xue-Yuan
XY
Liu
Fa-Rong
FR
Gou
Li-Na
LN
Guo
Xin-Hua
XH
Duan
Yong-Min
YM
Liang