Gemcitabine-related "pseudocellulitis": report of 2 cases and review of the literature.
Gemcitabine is a chemotherapeutic agent whose cutaneous toxicities are easily mistaken for infections. We describe 2 patients, 1 with gemcitabine-induced radiation recall dermatitis and 1 with gemcitabine-related erysipeloid reaction, who received misdiagnoses of infectious cellulitis and were given empirical antibiotics. Recognition of these syndromes is important to avoid unnecessary antibiotic use.
Tan
Darrell H S
DH
Division of Infectious Diseases, University Health Network, Toronto, ON. darrell.tan@gmail.com
Bunce
Paul E
PE
Liles
W Conrad
WC
Gold
Wayne L
WL
D000964:Antimetabolites, Antineoplastic / Q000009:adverse effects*; D002481:Cellulitis / Q000139:chemically induced* / Q000175:diagnosis / Q000382:microbiology; D003841:Deoxycytidine / Q000009:adverse effects / Q000031:analogs & derivatives*; D003951:Diagnostic Errors; D004890:Erythema / Q000139:chemically induced* / Q000175:diagnosis; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011855:Radiodermatitis / Q000139:chemically induced* / Q000175:diagnosis; D018714:Radiotherapy, Adjuvant; D000093542:Gemcitabine
D000964:Antimetabolites, Antineoplastic; D003841:Deoxycytidine; D000093542:Gemcitabine