Body weight and satiation after duodenal switch: 2 years later.
BACKGROUND
The authors investigated body weight, satiation, and gustative pleasure of obese patients 2 years after a bariatric operation: the biliopancreatic diversion with duodenal switch (DS).


METHODS
9 operated patients, 10 unoperated non-obese and 10 unoperated obese persons participated in the "alliesthesia (food distaste) test". This test is a psychometric assessment of satiation resulting from the pleasure or displeasure following the repeated ingestion of a sweet stimulus. Operated patients also participated in the test before the DS operation.


RESULTS
2 years after DS, patients had lost 50% of their body weight and their BMI was rendered similar to that of the non-obese control group. Their satiation was faster than in control and unoperated obese patients. The responses of control and unoperated obese patients were identical to those of pre-surgery operated patients.


CONCLUSIONS
This indicates that at the time of the experiment, patients' actual body weight was higher than their body weight set-point and that they would be likely to continue to lose weight, at least beyond 2 years.
Paradis
Sebastien
S
Centre de recherche sur le métabolisme énergétique (CREME), Anatomy and Physiology Department, Laval University, Québec, Canada.
Cabanac
Michel
M
Marceau
Picard
P
Frankham
Patrick
P
D015904:Biliopancreatic Diversion; D015992:Body Mass Index; D001835:Body Weight; D016022:Case-Control Studies; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D009767:Obesity, Morbid / Q000503:physiopathology* / Q000523:psychology* / Q000601:surgery; D012527:Satiation / Q000502:physiology*; D013997:Time Factors