[Crouzon syndrome: factors related to the neuropsychological development and to the quality of life].
Crouzon syndrome is characterized by cranial and facial abnormalities and exophtalmos. Mental retardation is sometimes observed. The objective of this study was to correlate brain malformations, timing for surgery and also social classification of families and parents education to the neuropsychological evaluation and to the quality of life of these families. Eleven patients with Crouzon syndrome were studied, whose ages were between 16 and 132 months. The multidisciplinary evaluation included : social evaluation, cognitive evaluation, brain studies by magnetic resonance imaging and quality of life evaluation. The intelligence quotient values observed were between 46 and 102 (m=84.2) and was correlated (inverted correlation) to the factor IV of the short-form of the Questionnaire on Resources and Stress. Mental development was not correlated to brain malformation, neither to the age at time of operation or to the level of family environment and parents education.
Departamento de Cirurgia Craniofacial, Hospital de Reabilitação de Anomalias Craniofaciais, Universidade de São Paulo, Bauru, SP, Brasil. adriano@yacubian.com.br
Adriano
A
Yacubian-Fernandes
Luis Gustavo
LG
Ducati
Mateus Violin
MV
Silva
Dagma Venturini Marques
DV
Abramides
Gimol B
GB
Perosa
Aristides
A
Palhares
Roberto C
RC
Gabarra
Alcir
A
Giglio
Luis
L
Portela
João Luiz P
JL
Marinello
José Píndaro P
JP
Plese
Silvio Antonio
SA
Zanini
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D003072:Cognition Disorders / Q000175:diagnosis / Q000209:etiology*; D003394:Craniofacial Dysostosis / Q000150:complications* / Q000523:psychology / Q000601:surgery; D004522:Educational Status; D005260:Female; D006801:Humans; D007223:Infant; D008279:Magnetic Resonance Imaging; D008297:Male; D009483:Neuropsychological Tests; D011788:Quality of Life; D012959:Socioeconomic Factors; D011795:Surveys and Questionnaires