[Influence of job-related factors on the clinical course of chronic hepatitis].
Although many workers suffer from chronic hepatitis, the influence of labor on its clinical course is not clear. We prospectively followed 89 workers with chronic hepatitis for 3 years, and examined the relationship between job-related factors, such as job class, job type, working hours and work effort, and the liver function test. There were no job-related factors that had any influence on the activity of hepatitis. Moreover, no significant relationship was found between job-related factors, including tiredness, and the acute exacerbation of hepatitis. No significant changes of aminotransferase levels and of platelet counts divided by each job-related factor were found during the observation period, but the platelet counts decreased in workers with acute exacerbation, but without clinical significance. These results suggest that job-related factors have little influence on the clinical course of chronic hepatitis during a relatively short observation period.
Department of Gastroenterology and Metabolism, University of Occupational and Environmental Health, Japan, School of Medicine.
Akinari
A
Tabaru
Hidehiko
H
Matsuoka
Satoru
S
Maekawa
Misa
M
Shimada
Ryoichi
R
Narita
Shintaro
S
Abe
Masahiro
M
Yamasaki
Mitsuo
M
Tashiro
Masashi
M
Taguchi
Mitsuyoshi
M
Yamamoto
Yasuyuki
Y
Kihara
Keiichiro
K
Kume
Ichiro
I
Yoshikawa
Hayato
H
Nakamura
Makoto
M
Otsuki
D000328:Adult; D005260:Female; D006521:Hepatitis, Chronic / Q000503:physiopathology; D006801:Humans; D008019:Life Style; D008111:Liver Function Tests; D008297:Male; D008875:Middle Aged; D009790:Occupations; D012907:Smoking / Q000453:epidemiology; D011795:Surveys and Questionnaires; D000637:Transaminases / Q000097:blood; D016526:Workload
D000637:Transaminases