[Assessment of depakine treatment of patients with endogen psychosis (clinical trial)].
The aim of the work is to research the effect of Depakin--anticonvulsant drug in the therapy of schizo-affective and affective psychosis in combination with antipsychotic drugs. Preparation Depakin-chrono, 500 mg tablets, was used in 20 patients, males of 25-45 years old. The daily dose of the drug varied 250-1500 mg/day. All the patients were characterized with the psychical diseases of endogen spectrum (attack-like schizophrenia, schizo-affective psychosis and manic-depressive psychosis). The results of the performed trials were positive. The expression of the side effects is not fixed. The drug combines with typical as well as atypical antipsychotic drugs quite well.
Kashia
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VSh
Bandzeladze
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LG
Nioradze
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Tkeshelashvili
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Tsitlidze
L M
LM
D000293:Adolescent; D000328:Adult; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D011618:Psychotic Disorders / Q000188:drug therapy*; D014635:Valproic Acid / Q000627:therapeutic use*
D014635:Valproic Acid