Chiral amine-polyoxometalate hybrids as highly efficient and recoverable asymmetric enamine catalysts.
Chiral amine and polyoxometalate (POM) acids were combined to give highly efficient, stereoselective, and recoverable enamine-based catalysts. Less than 1 mol % of chiral amine loading was sufficient for good catalytic activity, and the catalyst could be recovered and reused 6 times with unchanged enantioselectivity and slightly decreased activity.
Luo
Sanzhong
S
Beijing National Laboratory for Molecular Sciences (BNLMS), Center for Chemical Biology, Institute of Chemistry, Chinese Academy of Science, Beijing, 100080, China. luosz@iccas.ac.cn
Li
Jiuyuan
J
Xu
Hui
H
Zhang
Long
L
Cheng
Jin-Pei
JP
D000475:Alkenes / Q000737:chemistry*; D000588:Amines / Q000737:chemistry*; D002384:Catalysis; D015394:Molecular Structure; D011108:Polymers / Q000737:chemistry*; D013237:Stereoisomerism; D017973:Tungsten Compounds / Q000737:chemistry*; D000099294:Polyoxometalates
D000475:Alkenes; D000588:Amines; D011108:Polymers; D017973:Tungsten Compounds; C102296:polyoxometalate I; D000099294:Polyoxometalates