Cerebral vasospasm in shunt infection.
OBJECTIVE
In bacterial shunt infection, CNS inflammation is a frequently observed complication that may cause vascular complications including vasospasms. Here, we describe the first patient with shunt infection-induced cerebral vasospasms.


METHODS
A 35 year old woman with a ventriculoperitoneal shunt that was implanted years before developed facial nerve palsy and somnolence one week before admission to the hospital.


RESULTS
After admission, the shunt was removed, and an external ventricular drainage was inserted. Microbiological analyses revealed coagulase-negative Staphylococcus on abdominal and cranial catheters. Follow-up NMR showed infarctions. Transcranial doppler sonography and cerebral arteriography revealed severe generalized cerebral vasospasms. Inspite of triple-H therapy and intraarterial spasmolysis, bilateral anterior and media artery infarction evolved. The patient was dismissed in a vegetative state.


CONCLUSIONS
This case shows that severe cerebral vasospasms are a serious complication in patients with bacterial shunt infection that should be considered in patients, that don't improve following adequate antibiotic treatment.
Department of General Neurosurgery, University of Freiburg Medical School, Breisacher Str. 64, Freiburg 79106, Germany. martin.deininger@uni-tuebingen.de
Martin H
MH
Deininger
Ansgar
A
Berlis
Juergen
J
Buttler
D000328:Adult; D020806:Central Nervous System Bacterial Infections / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D003616:Dandy-Walker Syndrome / Q000628:therapy; D005260:Female; D006801:Humans; D013203:Staphylococcal Infections / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D020301:Vasospasm, Intracranial / Q000175:diagnosis* / Q000382:microbiology* / Q000628:therapy; D017287:Ventriculoperitoneal Shunt / Q000009:adverse effects*