[The role of apoptosis in induction ocular changes in patients with cystic fibrosis].
OBJECTIVE
To evaluate the concentration of sFas in tear film of cystic fibrosis patients.


METHODS
Tear samples were collected from 20 patients with cystic fibrosis and 20 patients from control group. The sFas levels were determined by immunoenzymatic assay ELISA.


RESULTS
We found statistically increased levels of sFas in tear film of patients with cystic fibrosis compared with control group.


CONCLUSIONS
Apoptosis may play role in the pathogenesis of ocular changes in cystic fibrosis patients. The above results are important for the choice of the treatment of dry eye syndrome in patients with cystic fibrosis.
Mrugacz
Małgorzata
M
Kliniki Okulistyki Dzieciecej, Akademii Medycznej w Białymstoku.
Zelazowska-Rutkowska
Beata
B
Bakunowicz-Lazarczyk
Alina
A
Wysocka
Jolanta
J
Kaczmarski
Maciej
M
D000293:Adolescent; D000328:Adult; D017209:Apoptosis; D016022:Case-Control Studies; D002648:Child; D003550:Cystic Fibrosis / Q000378:metabolism*; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D008297:Male; D013666:Tears / Q000737:chemistry*; D019014:fas Receptor / Q000032:analysis*
D019014:fas Receptor