Efficacy of autovaccination therapy on post-coronary artery bypass grafting methicillin-resistant Staphylococcus aureus mediastinitis.
We report a case of mediastinitis successfully treated with autovaccine therapy, once conventional surgical and medical therapies had failed.
Rizzo
Caterina
C
Department of Pharmaco-Biology, University of Bari, Italy.
Brancaccio
Gianluca
G
De Vito
Danila
D
Rizzo
Giovanni
G
D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000891:Anti-Infective Agents, Local / Q000627:therapeutic use; D001026:Coronary Artery Bypass; D023921:Coronary Stenosis / Q000601:surgery*; D003646:Debridement; D005839:Gentamicins / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008480:Mediastinitis / Q000188:drug therapy / Q000382:microbiology / Q000601:surgery / Q000628:therapy*; D016106:Methicillin Resistance; D011206:Povidone-Iodine / Q000627:therapeutic use; D013203:Staphylococcal Infections / Q000188:drug therapy / Q000382:microbiology / Q000601:surgery / Q000628:therapy*; D013209:Staphylococcal Vaccines / Q000627:therapeutic use*; D013211:Staphylococcus aureus / Q000276:immunology* / Q000302:isolation & purification; D013530:Surgical Wound Infection / Q000188:drug therapy / Q000382:microbiology / Q000601:surgery / Q000628:therapy*; D017334:Teicoplanin / Q000627:therapeutic use; D007507:Therapeutic Irrigation; D017211:Treatment Failure; D016896:Treatment Outcome; D014640:Vancomycin / Q000627:therapeutic use
D000900:Anti-Bacterial Agents; D000891:Anti-Infective Agents, Local; D005839:Gentamicins; D013209:Staphylococcal Vaccines; D017334:Teicoplanin; D014640:Vancomycin; D011206:Povidone-Iodine