Norditerpenoid and dianthramide glucoside alkaloids from cultivated Aconitum species from korea.
A new norditerpene alkaloid named 8-O-methylhypaconine (1) was isolated along with twelve known alkaloids from the underground parts of an unknown species of Aconitum plant culti vated in Korea. Among the known alkaloids, two dianthramide glucosides, N-(2'-beta-glucopyra nosyl-5'-hydroxysalicyl)-5-hydroxyanthranilic acid methyl ester (2) and N-(2'-beta-glucopyranosyl-5'-hydroxysalicyl)-5-hydroxy-6-methoxyanthranilic acid methyl ester (3), were isolated from Aconitum plants for the first time. The structures were established on the basis of chemical and spectroscopic methods.
Lee
So Young
SY
Natural Products Research Institute and College of Pharmacy, Seoul National University, Jongno-gu, Seoul 110-460, Korea.
Shim
Sang Hee
SH
Kim
Ju Sun
JS
Lee
Je-Hyun
JH
Lee
Ho Young
HY
Jung
Da-Young
DY
Ha
Hyekyung
H
Kim
Chungsook
C
Kang
Sam Sik
SS
D031841:Aconitum / Q000737:chemistry*; D000470:Alkaloids / Q000737:chemistry* / Q000302:isolation & purification; D004224:Diterpenes / Q000737:chemistry* / Q000302:isolation & purification; D007723:Korea; D009682:Magnetic Resonance Spectroscopy; D021241:Spectrometry, Mass, Electrospray Ionization; D013055:Spectrophotometry, Infrared
C523165:8-O-methylhypaconine; D000470:Alkaloids; D004224:Diterpenes