Molecular mechanisms of resistance to heavy metals in the protist Euglena gracilis.
The biochemical mechanisms of resistance to several heavy metals, which are associated with their accumulation (binding by high-affinity chelating molecules such as thiol-compounds together with their compartmentalization into organelles), are analyzed for the photosynthetic, free-living protist Euglena gracilis. The complete understanding of these mechanisms may facilitate the rational design of strategies for bioremediation of heavy metal polluted water and soil systems.
Rodríguez-Zavala
José S
JS
Departamento de Bioquímica, Instituto Nacional de Cardiología, Mexico.
García-García
Jorge D
JD
Ortiz-Cruz
Marco A
MA
Moreno-Sánchez
Rafael
R
D000222:Adaptation, Physiological; D000818:Animals; D001673:Biodegradation, Environmental; D002736:Chloroplasts / Q000378:metabolism; D005056:Euglena gracilis / Q000187:drug effects* / Q000378:metabolism; D005978:Glutathione / Q000378:metabolism; D019216:Metals, Heavy / Q000633:toxicity*; D054811:Phytochelatins; D014874:Water Pollutants, Chemical / Q000633:toxicity*
D019216:Metals, Heavy; D014874:Water Pollutants, Chemical; D054811:Phytochelatins; D005978:Glutathione