Design and development of a flow injection-capillary electrophoresis analyzer employing fiber optic detection.
The development and experimental optimization of a novel flow injection-capillary electrophoresis (FI-CE) analyzer employing UV-visible fiber optic detection is described. The analyzer incorporates a miniature charge-coupled device (CCD) spectrometer and operates in a graphical programming environment. Data from experimental optimization studies and small molecule separations involving affinity capillary electrophoresis (ACE) and indirect detection of anions are presented. Future directions in terms of instrument automation and incorporation into a microfluidic format are also discussed.
Department of Chemistry & Biochemistry, California State University, Los Angeles, CA 90032, USA. ghanrah@calstatela.edu
Grady
G
Hanrahan
Florence
F
Tse
Froseen T
FT
Dahdouh
Keith
K
Clarke
Frank A
FA
Gomez
D019075:Electrophoresis, Capillary / Q000295:instrumentation* / Q000379:methods*; D005336:Fiber Optic Technology / Q000295:instrumentation* / Q000379:methods*; D017022:Flow Injection Analysis; D005998:Glycine; D055100:Optical Fibers; D014640:Vancomycin
D014640:Vancomycin; D005998:Glycine