Are complex carcinoma of the feline mammary gland and other invasive mammary carcinoma identical tumours? Comparison of clinicopathologic features, DNA ploidy and follow up.
Feline mammary carcinomas are known for their unfavourable prognosis due to a strong tendency to local recurrence and metastasis. We studied 73 spontaneous primary mammary carcinomas and identified eight cases presenting a biphasic nature, with neoplastic epithelial and myoepithelial cells (complex carcinoma). These cases presented histopathologic features associated with a better prognosis; they were also associated with higher overall survival and disease-free survival rates compared to other common invasive mammary carcinomas of non-specified type. Complex carcinoma appears to be a low-grade malignancy.
Department of Veterinary Sciences, Veterinary Teaching Hospital, CECAV, University of Trás-os-Montes e Alto Douro, 5000-811 Vila Real, Portugal. fseixas@utad.pt
Fernanda
F
Seixas
Carlos
C
Palmeira
Maria Anjos
MA
Pires
Carlos
C
Lopes
D000818:Animals; D002371:Cat Diseases / Q000235:genetics* / Q000473:pathology* / Q000601:surgery; D002415:Cats; D004273:DNA, Neoplasm / Q000235:genetics*; D005260:Female; D007700:Kinetics; D015674:Mammary Neoplasms, Animal / Q000235:genetics* / Q000473:pathology / Q000601:surgery; D015409:Mastectomy, Radical / Q000662:veterinary; D008938:Mitosis; D009361:Neoplasm Invasiveness / Q000473:pathology; D011003:Ploidies
D004273:DNA, Neoplasm