Primitive neuroectodermal tumor of the myometrium with cardio-vascular symptoms.
BACKGROUND
Non-bacterial thrombotic endocarditis is a severe complication of cancer, rarely reported in gynecologic tumors. However, it can be inaugural and lead to complex diagnostic pathways.


METHODS
A 40-year-old woman presented with a stroke, related to an endocarditis. The valvular vegetation was surgically removed, and a malignant node was resected. A PET-scan led to the diagnosis of a myometrial tumor, which was found to be a primitive neuroectodermal tumor (PNET). The patient underwent total abdominal hysterectomy with bilateral salpingo-oophorectomy, and systemic chemotherapy which allowed a complete remission of tumoral and cardio-vascular symptoms.


CONCLUSIONS
To our knowledge, this is the first case report of a PNET of the myometrium revealed by cardio-vascular symptoms.
Mir
Olivier
O
Department of Oncology, Assistance Publique - Hôpitaux de Paris, Hôpital Cochin, University Paris 5, Faculty of Medicine, Paris, France. olivier.mir@cch.aphp.fr
Albiges
Laurence
L
Arkwright
Sylviane
S
Duboc
Denis
D
Massault
Pierre-Philippe
PP
Tenenbaum
Florence
F
Touzé
Emmanuel
E
Menasché
Philippe
P
Vacher-Lavenu
Marie-Cécile
MC
Goldwasser
François
F
Alexandre
Jérôme
J
D000328:Adult; D004696:Endocarditis / Q000209:etiology*; D005260:Female; D006801:Humans; D018242:Neuroectodermal Tumors, Primitive / Q000150:complications* / Q000601:surgery; D014594:Uterine Neoplasms / Q000150:complications* / Q000601:surgery