Prolonged residual paralysis after a single intubating dose of rocuronium.
It is often argued that neuromuscular monitoring is unnecessary when only one dose of an intermediate-acting neuromuscular blocking agent is given. This case report documents that it may take more than 3.5 h before it is possible to antagonize a block caused by a normal dose of rocuronium (0.6 mg kg(-1)). Possible causes of the extremely prolonged duration of action are discussed, as is the importance of quantitative neuromuscular monitoring.
Department of Anaesthesia and Intensive Care, Copenhagen University Hospital, Rigshospitalet, Blegdamsvej 9, DK-2100 Copenhagen, Denmark. casperclaudius@dadlnet.dk
C
C
Claudius
H
H
Karacan
J
J
Viby-Mogensen
D000369:Aged, 80 and over; D000732:Androstanols / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008991:Monitoring, Physiologic; D009469:Neuromuscular Junction / Q000187:drug effects / Q000502:physiology; D003473:Neuromuscular Nondepolarizing Agents / Q000009:adverse effects*; D010243:Paralysis / Q000139:chemically induced*; D011183:Postoperative Complications; D011184:Postoperative Period; D000077123:Rocuronium
D000732:Androstanols; D003473:Neuromuscular Nondepolarizing Agents; D000077123:Rocuronium