The minimum information about a proteomics experiment (MIAPE).
Both the generation and the analysis of proteomics data are now widespread, and high-throughput approaches are commonplace. Protocols continue to increase in complexity as methods and technologies evolve and diversify. To encourage the standardized collection, integration, storage and dissemination of proteomics data, the Human Proteome Organization's Proteomics Standards Initiative develops guidance modules for reporting the use of techniques such as gel electrophoresis and mass spectrometry. This paper describes the processes and principles underpinning the development of these modules; discusses the ramifications for various interest groups such as experimentalists, funders, publishers and the private sector; addresses the issue of overlap with other reporting guidelines; and highlights the criticality of appropriate tools and resources in enabling 'MIAPE-compliant' reporting.
The HUPO Proteomics Standards Initiative, Wellcome Trust Genome Campus, Hinxton, Cambridgeshire CB10 1SD, UK. chris.taylor@ebi.ac.uk
Chris F
CF
Taylor
Norman W
NW
Paton
Kathryn S
KS
Lilley
Pierre-Alain
PA
Binz
Randall K
RK
Julian
Andrew R
AR
Jones
Weimin
W
Zhu
Rolf
R
Apweiler
Ruedi
R
Aebersold
Eric W
EW
Deutsch
Michael J
MJ
Dunn
Albert J R
AJ
Heck
Alexander
A
Leitner
Marcus
M
Macht
Matthias
M
Mann
Lennart
L
Martens
Thomas A
TA
Neubert
Scott D
SD
Patterson
Peipei
P
Ping
Sean L
SL
Seymour
Puneet
P
Souda
Akira
A
Tsugita
Joel
J
Vandekerckhove
Thomas M
TM
Vondriska
Julian P
JP
Whitelegge
Marc R
MR
Wilkins
Ioannnis
I
Xenarios
John R
JR
Yates
Henning
H
Hermjakob
D030562:Databases, Protein / Q000592:standards*; D020869:Gene Expression Profiling / Q000592:standards*; D015894:Genome, Human / Q000235:genetics*; D017408:Guidelines as Topic; D006801:Humans; D016247:Information Storage and Retrieval / Q000592:standards*; D038622:Internationality; D040901:Proteomics / Q000592:standards*; D012106:Research / Q000592:standards*