[Procedural memory and brain SPECT: blood flow evaluation in the cerebellum and pre-frontal cortex during a visuo-motor task].
The objective of the present study was to evaluate the cerebral blood flow in the cerebellar (4 sub-regions) and pre-frontal cortex, when subjects were in rest and during a motor task performance. The sample consisted of 8 healthy subjects, male or female, between 23 and 36 of age. The visuo-motor task - implicit memory - requires the subjects to navigate and swerve a graphic submarine from missiles that run on the screen. Semi-quantitative analysis with brain SPECT (99mTc-ECD) was used to evaluate regional perfusion. The results revealed an increased activity in all areas of interest during motor task. In conclusion, four sub-regions of cerebellar cortex and both pre-frontal hemispheres showed a simultaneous activation during task. Moreover, our findings suggest as seen in previous experiments that the central nervous system operates in a parallel fashion, in order to integrate sensory and motor information.
Silva
Márcia Thereza
MT
Laboratório de Mapeamento Cerebral e Integração Sensório-Motora, Instituto de Psiquiatria do Rio de Janeiro, Universidade Federal do Rio de Janeiro, Brasil. marciather@ig.com.br
Piedade
Roberto
R
Ribeiro
Pedro
P
Fonseca
Léa Mirian B da
LM
Pellini
Marcos Pinto
MP
Cagy
Maurício
M
D000328:Adult; D002531:Cerebellum / Q000098:blood supply* / Q000000981:diagnostic imaging; D002540:Cerebral Cortex / Q000098:blood supply* / Q000000981:diagnostic imaging; D002560:Cerebrovascular Circulation / Q000502:physiology*; D003545:Cysteine / Q000031:analogs & derivatives; D005260:Female; D006801:Humans; D008297:Male; D008568:Memory / Q000502:physiology*; D015609:Organotechnetium Compounds; D011597:Psychomotor Performance / Q000502:physiology*; D019275:Radiopharmaceuticals; D015899:Tomography, Emission-Computed, Single-Photon
D015609:Organotechnetium Compounds; D019275:Radiopharmaceuticals; C059659:technetium Tc 99m bicisate; D003545:Cysteine