[The character of dyslipidemia and myocardial and carotid arterial remodeling in young patients with essential hypertension].
The purpose of the investigation was to study the character of myocardial and vascular revascularization by the example of the carotid artery (CA) in young patients with arterial hypertension in correlation with biochemical and clinical data. Sixty-eight patients were examined. EchoCG and sonography were performed using SONOS 4500 device. Left ventricular myocardial mass (LVMM) was calculated using R. Devereus formula. Intimomedial thickness (IMT) was measured in the ostium of the common CA (CCA) bifurcation. Lipidogram was performed by "dry chemistry" method using Reflotron bioanalyzer. An elevated LVMM index was revealed in 65% of the subjects. Concentric left ventricular (LV) hypertrophy prevailed over other types of myocardial remodeling (53%). LV diastolic dysfunction was found in 23% of the patients; LV systolic dysfunction was revealed in 56% of the subjects. IMT was increased in 27% of cases, C- and S-shape curvatures were revealed in 56.6% of the patients. In 31.3% of the subjects, atherosclerotic plaques with a 20% to 50% stenosis were found. Various forms of dyslipidemia were revealed in 75.6% of the patients. In conclusion, dyslipidemia and lesion of target organs in a form of myocardial and vascular remodeling require active antihypertensive and hypolipidemic therapy to prevent complications.
Bazina
I B
IB
Bogachev
R S
RS
Rafeenkova
V S
VS
Kostina
N I
NI
Solov'eva
N V
NV
D000328:Adult; D002340:Carotid Artery Diseases / Q000453:epidemiology* / Q000503:physiopathology*; D050171:Dyslipidemias / Q000453:epidemiology* / Q000503:physiopathology*; D004452:Echocardiography; D005260:Female; D006801:Humans; D006973:Hypertension / Q000453:epidemiology* / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000453:epidemiology* / Q000503:physiopathology; D012720:Severity of Illness Index; D020257:Ventricular Remodeling / Q000502:physiology*