Thermodynamics of phosphopeptide tethering to BRCT: the structural minima for inhibitor design.
Chemical Biology Program, Department of Pharmacology and Toxicology, Sealy Center for Structural Biology, University of Texas Medical Branch, Galveston, Texas 77555, USA.
G L
GL
Lokesh
B K
BK
Muralidhara
Surendra S
SS
Negi
Amarnath
A
Natarajan
D019313:BRCA1 Protein / Q000737:chemistry*; D050976:Basic-Leucine Zipper Transcription Factors / Q000737:chemistry; D051856:Fanconi Anemia Complementation Group Proteins / Q000737:chemistry; D005454:Fluorescence Polarization; D006801:Humans; D057927:Hydrophobic and Hydrophilic Interactions; D008958:Models, Molecular; D010748:Phosphopeptides / Q000737:chemistry*; D011485:Protein Binding; D017434:Protein Structure, Tertiary; D013816:Thermodynamics
C102108:BACH1 protein, human; D019313:BRCA1 Protein; D050976:Basic-Leucine Zipper Transcription Factors; D051856:Fanconi Anemia Complementation Group Proteins; D010748:Phosphopeptides