Childhood hearing is associated with growth rates in infancy and adolescence.
It is known that shorter stature is associated with sensorineural hearing loss; and that cochlear development is associated with activity of IGF 1, as are many important aspects of neurodevelopment. We hypothesized that this relation might be extrapolated to a normally hearing group, and that the strongest relation between hearing level and growth rate would be in late puberty, when serum IGF-1 levels are highest. We examined the statistical relation between childhood hearing threshold and rate of growth in height at different times during the life course up to age 32. We found mixed support for the hypothesis. The strongest relations were observed in late puberty, at the ages which previous research shows are associated with the highest serum concentrations of IGF-1 in males and females, but also in infancy and early childhood. The association between hearing and height is present in a normally hearing, general population sample, and is associated with growth in late adolescence. Our findings support the idea that childhood hearing threshold may be predictive of IGF-1 mediated developmental characteristics.
Welch
David
D
Department of Preventive and Social Medicine, Dunedin School of Medicine, University of Otago, Dunedin 9054, New Zealand. david.welch@dmhdru.otago.ac.nz
Dawes
Patrick J D
PJ
D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000375:Aging / Q000378:metabolism / Q000502:physiology*; D001309:Auditory Threshold; D001827:Body Height; D002648:Child; D002675:Child, Preschool; D003051:Cochlea / Q000254:growth & development / Q000378:metabolism; D005260:Female; D006309:Hearing / Q000502:physiology*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007334:Insulin-Like Growth Factor I / Q000378:metabolism; D008137:Longitudinal Studies; D008297:Male; D011627:Puberty / Q000378:metabolism
D007334:Insulin-Like Growth Factor I