Calculation of the minimum significant difference at the NOEC using a non-parametric test.
The minimum significant difference (MSD) at the no observed effect concentration (NOEC) is required in many guidelines for standardised ecotoxicological tests. A method is given to calculate the MSD if non-parametric pair-wise comparison of each concentration with the control is used to determine the NOEC.
van der Hoeven
Nelly
N
ECOSTAT, Vondellaan 23, 2332 AA Leiden, The Netherlands. NvdH@ecostat.nl
D064420:Drug-Related Side Effects and Adverse Reactions; D019055:No-Observed-Adverse-Effect Level; D018709:Statistics, Nonparametric; D018675:Toxicity Tests / Q000706:statistics & numerical data*