[Alcohol intake and gamma -GTP observed from the viewpoint of an occupational physician].
Alcohol is an important basic factor in health management at the workplace. The fact is, however, when alcohol is pervasive in a worker's daily life, effective measures are very difficult to carry out. We examined an intervention program based on serum y -GTP (IU/l) measurements at physical examination. Subjects were clients of the Keio Counseling Center in2005 (male, 5568: female, 1725). Among nondrinkers, gamma-GTP values were under 50 in 83% of men and 93% of women. Relative risk of lifestyle-related diseases (obesity, hypertension, hyperlipidemia, hyperuricemia, hyperglycemia and fatty liver) among male drinkers increased dramatically when gamma-GTP exceeded 50,with a further gradual increase for gamma-GTP over 100. Moreover, relative risk of over two concurrent diseases among obesity, hypertension, hyperlipidemia and hyperglycemia increased when gamma-GTP exceeded 25 and greatly increased beyond 50. While the findings suggest 25 or less as an ideal gamma-GTP values, a workplace program might more practically regard values over 50 as a threshold for management measures and values over 100 as indicating enforced management. At the workplace, management of other diseases including lifestyle-related diseases, alcoholism per se, and mental health issues needs to be carried out in a balanced, coordinated manner. Cooperation of related medical institutions and effective alcohol treatment program, and efforts to enlist the understanding and trust of all workers are needed.
The Bank of Tokyo-Mitsubishi-UFJ Medical Center, Otemachi Office, 1-1, Otemachi 1-Chome, Chiyoda-ku, Tokyo, Japan.
Takamitsu
T
Oikawa
D000328:Adult; D000428:Alcohol Drinking / Q000009:adverse effects / Q000517:prevention & control; D019973:Alcohol-Related Disorders / Q000175:diagnosis / Q000209:etiology* / Q000517:prevention & control; D015415:Biomarkers / Q000097:blood; D005260:Female; D006801:Humans; D008019:Life Style; D008297:Male; D008603:Mental Health; D024821:Metabolic Syndrome / Q000175:diagnosis / Q000209:etiology* / Q000517:prevention & control; D008875:Middle Aged; D016272:Occupational Health; D012306:Risk; D017132:Workplace; D005723:gamma-Glutamyltransferase / Q000097:blood*
D015415:Biomarkers; D005723:gamma-Glutamyltransferase