[Comparative characteristics of clinical-laboratory data and echography monitoring of the processes of folliculogenesis at hyperandrogenia syndrome].
Comparison of the data of clinical-laboratory examination and study of the specific features of folliculogenesis and ovulatory disorders in patients with ovary (167) and adrenal (76) hyperandrogenia (OHA and AHA) was conducted. As a result of the research, a significant increase of LH, combined with the decreased level of FSH, is determined in the patients with polycystic ovary syndrome, vs. the control group. Interrelations in the hypothalamic-hypophyseal-ovarial system are characterized by significant correlations between the levels of FSH and LH, estradiol and progesterone. Compared with the control group, the patients with adrenal hyperandrogemia showed a significant decrease of FSH and estradiol levels in the blood, and significant correlations between the levels of LH and FSH, LH and estradiol in the blood. Significant correlations between the content of testosterone and LH in the blood may be indicative of the definite role, played by the change of steroidogenesis in the ovaries of the patients with hyper function of adrenal cortex. As a result of the multivariant analysis of the data of echography monitoring of the processes of folliculogenesis in the patients with hyperandrogenia syndrome, along with the well-known, in the group of patients with ovary hyperandrogenia, an ovular disorders of defective, "sub capsular" type, or intra ovarian ovulation have also been stated, when no complete destruction of the ovulating follicle wall happens, and the integrity of theca interna is only impaired, while theca externa remains intact. At that, blood flows into the opening of the not ovulating follicle, which often entails pronounced pain syndrome.
Tokhunts
K A
KA
Abramian
R A
RA
Abramian
L R
LR
D000311:Adrenal Glands / Q000000981:diagnostic imaging / Q000503:physiopathology; D005260:Female; D005498:Follicular Phase / Q000502:physiology*; D006801:Humans; D017588:Hyperandrogenism / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D007753:Laboratories; D010053:Ovary / Q000000981:diagnostic imaging / Q000503:physiopathology; D014463:Ultrasonography