Reactivity-based fluoride detection: evolving design principles for spring-loaded turn-on fluorescent probes.
A covalently triggered fluorescence turn-on detection scheme has been implemented for a tris(N-salicylideneamine)-derived dynamic fluorophore. Selective cleavage of strategically placed Si-O bonds by fluoride ion induces spring-loaded conformational transitions that are tightly coupled to fluorescence enhancement.
Jiang
Xuan
X
Department of Chemistry, Indiana University, 800 East Kirkwood Avenue, Bloomington, Indiana 47405, USA.
Vieweger
Mario C
MC
Bollinger
John C
JC
Dragnea
Bogdan
B
Lee
Dongwhan
D
D018360:Crystallography, X-Ray; D005456:Fluorescent Dyes / Q000737:chemistry*; D005459:Fluorides / Q000032:analysis* / Q000737:chemistry; D007477:Ions; D015394:Molecular Structure; D010100:Oxygen / Q000737:chemistry*; D012545:Schiff Bases / Q000737:chemistry*; D012825:Silicon / Q000737:chemistry*
D005456:Fluorescent Dyes; D007477:Ions; D012545:Schiff Bases; C513910:tris(salicylideneamine); D005459:Fluorides; D010100:Oxygen; D012825:Silicon