[Sinus rhythm variability in bronchial asthma].
The subjects, 265 patients with bronchial asthma (BA) patients (mean age: 41.92 +/- 1.36 yr), were examined using spirometry, peak-flowmetry, body plethysmography, EchoCG, and bronchoscopy with biopsy and histologic study. A high-resolution method--rhythmocardiography with temporal statistical and spectral analysis of sinus rhythm variability at rest and at directed testing using hardware and software complex KAP-RK-01-Micor (Chelyabinsk)--was applied. The patients with BA displayed sinus node dysregulation, insufficient vegetative providence, significant depression of peripheral sympathico-parasympathetic regulation in general, intensification of humoral-and-metabolic influence on pacemaker cells in the sinus node, and the forming of a pathophysiological pattern of response to stimuli during tests.
A V
AV
Kalmykova
T F
TF
Mironova
V A
VA
Mironov
D001249:Asthma / Q000453:epidemiology* / Q000503:physiopathology*; D006801:Humans; D013616:Tachycardia, Sinus / Q000453:epidemiology* / Q000503:physiopathology*