Methods in cell separations.
Research in the field of cell biology and biomedicine relies on technologies that fractionate cell populations and isolate rare cell types to high purity. A brief overview of methods and commercially available products currently used in cell separations is presented. Cell fractionation by size and density and highly selective affinity-based technologies such as affinity chromatography, fluorescence-activated cell sorting (FACS) and magnetic cell sorting are discussed in terms of throughput, yield, and purity.
Department of Biotechnology, Center for Chemistry and Chemical Engineering, Lund University, Lund, Sweden.
Maria B
MB
Dainiak
Ashok
A
Kumar
Igor Yu
IY
Galaev
Bo
B
Mattiasson
D000818:Animals; D002469:Cell Separation / Q000379:methods*; D002846:Chromatography, Affinity; D005434:Flow Cytometry; D005453:Fluorescence; D006801:Humans; D018189:Immunomagnetic Separation