Amniotic membrane grafting for conjunctival and lid surface disease in the acute phase of toxic epidermal necrolysis.
Toxic epidermal necrolysis (TEN) is a severe form of Stevens-Johnson syndrome, characterized by extensive sloughing of mucous membranes and skin. It is associated with mortality rates of up to 70% and significant ocular morbidity in long-term survivors. We present a case of TEN with severe bilateral ocular involvement in whom we successfully used amniotic membrane grafts to treat the ocular surface during the acute phase of the disease.
Tandon
Anamika
A
Princess Alexandra Eye Pavilion, Edinburgh, Scotland, UK.
Cackett
Peter
P
Mulvihill
Alan
A
Fleck
Brian
B
D000208:Acute Disease; D000650:Amnion / Q000637:transplantation*; D002648:Child; D003229:Conjunctival Diseases / Q000601:surgery*; D005141:Eyelid Diseases / Q000601:surgery*; D005260:Female; D006801:Humans; D013262:Stevens-Johnson Syndrome / Q000601:surgery*