[Epidemiological profile and antibiotic susceptibility of Pseudomonas aeruginosa isolates within the burned patient hospitalized in the intensive care burn unit].
BACKGROUND
Pseudomonas aeruginosa plays a predominant role as an etiological agent involved in serious infections in burned patients. Treatment of these infections is frequently complicated by antibiotic resistance, a problem that is is increasing in recent years.


OBJECTIVE
The objective of this study is to analyze epidemiological profile and antibiotic susceptibility of P. aeruginosa isolates within the burned patients admitted in our intensive care department.


METHODS
During a period of 4 years (2000/2003), 828 burn patients were admitted.


RESULTS
The survey of antibiotic susceptibility of P. aeruginosa showed high percentages of resistance to the different antibiotics. 60.9% of strains were resistant to piperacillin, 53.4% to ceftazidime, 37.6% to imipenem, 70.6% to cefsulodine, 59.3% to tobramycin, 80% to gentamicin, 62.4% to amikacin and 53.4% to ciprofloxacin.


CONCLUSIONS
It is necessary to implement urgent measures to prevent the spreading of this multiresistant strain. These measures include: sensible limitation of the use of antimicrobial agent, strict disinfection and hygienic procedures.
Service de réanimation des brûlés, Hôpital Aziza Othmana, Tunis de Tunis.
Thabet
T
Lamia
K
K
Bousselmi
Ben Redjeb
BR
Saida
Messadi Amen
MA
Allah
D000293:Adolescent; D000328:Adult; D000368:Aged; D002053:Burn Units; D002056:Burns / Q000453:epidemiology / Q000382:microbiology*; D002648:Child; D003428:Cross Infection / Q000188:drug therapy / Q000382:microbiology; D024901:Drug Resistance, Multiple, Bacterial; D006801:Humans; D007362:Intensive Care Units; D008875:Middle Aged; D011552:Pseudomonas Infections / Q000188:drug therapy*; D011550:Pseudomonas aeruginosa / Q000302:isolation & purification; D014416:Tunisia / Q000453:epidemiology