Prolonged residual paralysis after a single intubating dose of rocuronium.
It is often argued that neuromuscular monitoring is unnecessary when only one dose of an intermediate-acting neuromuscular blocking agent is given. This case report documents that it may take more than 3.5 h before it is possible to antagonize a block caused by a normal dose of rocuronium (0.6 mg kg(-1)). Possible causes of the extremely prolonged duration of action are discussed, as is the importance of quantitative neuromuscular monitoring.
Claudius
C
C
Department of Anaesthesia and Intensive Care, Copenhagen University Hospital, Rigshospitalet, Blegdamsvej 9, DK-2100 Copenhagen, Denmark. casperclaudius@dadlnet.dk
Karacan
H
H
Viby-Mogensen
J
J
D000369:Aged, 80 and over; D000732:Androstanols / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008991:Monitoring, Physiologic; D009469:Neuromuscular Junction / Q000187:drug effects / Q000502:physiology; D003473:Neuromuscular Nondepolarizing Agents / Q000009:adverse effects*; D010243:Paralysis / Q000139:chemically induced*; D011183:Postoperative Complications; D011184:Postoperative Period; D000077123:Rocuronium
D000732:Androstanols; D003473:Neuromuscular Nondepolarizing Agents; D000077123:Rocuronium