Equine metabolic myopathies with emphasis on the diagnostic approach. Comparison with human myopathies. A review.
This review gives an overview of the presently known human and equine metabolic myopathies with emphasis on the diagnostic approach. Metabolic myopathies are muscle disorders caused by a biochemical defect of the skeletal muscle energy system, which results in inefficient muscle performance. Myopathies can arise in different levels of the metabolic system. In this review the metabolic myopathies are categorized in disorders of the carbohydrate metabolism, lipid metabolism, mitochondrial myopathies (other than those described in lipid metabolism), disorders of purine metabolism, primary disorders involving ion channels and electrolyte flux and secondary or acquired metabolic myopathies.
Department of Equine Sciences, Medicine Section, Faculty of Veterinary Medicine, Utrecht University, The Netherlands. C.M.Westermann@vet.uu.nl
C M
CM
Westermann
L
L
Dorland
I D
ID
Wijnberg
J H
JH
van der Kolk
D000818:Animals; D006734:Horse Diseases / Q000175:diagnosis* / Q000473:pathology; D006736:Horses; D006801:Humans; D008661:Metabolism, Inborn Errors / Q000175:diagnosis / Q000662:veterinary*; D017240:Mitochondrial Myopathies / Q000175:diagnosis / Q000662:veterinary*; D013045:Species Specificity