[Study on chemical constiuents from Ligularia intermedia of shanxi].
OBJECTIVE
To study the chemical constituents of Ligularia intermedia of Shanxi.


METHODS
The compounds were isolated by column chromatography on silica gel and preparative TLC. The structures were identified by IR, MS, 1D/2DNMR spectral data and X-ray single crystal diffraction and other methods1.


RESULTS
Nine compound were isolated and identified as 8beta-hydroxyeremophil-7(11)-ene-12, 8alpha(4beta, 6alpha)-diolide (1), 8beta-methoxyeremophil-7(11)-ene-12, 8alpha(4beta, 6alpha)-diolide (2), petasin (3), isopetasin (4), liguhodgsonal (5), ligudentatol (6), ligujapone (7), lupeol (8) and lupeol palmitate (9).


CONCLUSIONS
Compounds 2, 3, 4, 6, 7 and 9 were isolated from the plant for the first time.
Xue
Hui-qing
HQ
Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000, China.
Ma
Xue-mei
XM
Wei
Xiao-ning
XN
Wu
Sui-xian
SX
Wang
Han-qing
HQ
D019659:Asteraceae / Q000737:chemistry*; D008968:Molecular Conformation; D015394:Molecular Structure; D010946:Plants, Medicinal / Q000737:chemistry*; D012717:Sesquiterpenes / Q000737:chemistry / Q000302:isolation & purification*; D013237:Stereoisomerism
D012717:Sesquiterpenes; C418727:petasin; C418728:isopetasin