Prevention of allergic diseases.
The prevalence of asthma and allergic diseases has increased in recent years, particularly in the industrialized world. Allergic disease begins to manifest in the first years of life. The disorder usually manifests initially in the form of food allergy and atopic dermatitis, followed in later stages by respiratory allergy with rhinitis and/or asthma. This has led to the adoption of preventive measures in those children with a high risk of atopy, based on the following considerations: 1) A family history of allergic diseases (asthma, eczema, and/or allergic rhinitis); 2) A personal history of atopy such as atopic dermatitis, particularly when associated to food allergy; and 3) The existence of allergic sensitization, particularly to pneumoallergens, of early or late onset, but persistent during childhood. Prevention is established at three different levels: primary prevention, avoiding sensitization; secondary prevention, avoiding appearance of the disease; and tertiary prevention, avoiding the symptoms. The present study discusses current knowledge of prevention and its efficacy, with mention of the importance of breastfeeding and the use of pre- and probiotics for securing adequate prevention.
Pediatric Allergy Unity, Universitary Hospital, Salamanca, Spain. lorente@usal.es
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F
Lorente
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M
Isidoro
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I
Dávila
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E
Laffond
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E
Moreno
D000293:Adolescent; D000328:Adult; D000485:Allergens / Q000009:adverse effects; D018926:Anti-Allergic Agents / Q000627:therapeutic use; D001249:Asthma / Q000188:drug therapy / Q000517:prevention & control; D002648:Child; D002675:Child, Preschool; D004782:Environmental Health; D005069:Evaluation Studies as Topic; D006801:Humans; D006967:Hypersensitivity / Q000188:drug therapy / Q000517:prevention & control*; D006969:Hypersensitivity, Immediate / Q000517:prevention & control; D007223:Infant; D007225:Infant Food / Q000009:adverse effects; D007231:Infant, Newborn; D008895:Milk, Human; D011322:Primary Prevention / Q000379:methods; D055502:Secondary Prevention
D000485:Allergens; D018926:Anti-Allergic Agents