Role of active and passive smoking on lung cancer etiology in Mexico City.
OBJECTIVE
[corrected] To estimate the association between passive and active smoking exposures and lung cancer in Mexico City and the corresponding attributable risks.


METHODS
Data was analyzed from a multicenter population-based case-control study conducted in Mexico City.


RESULTS
ORs for lung cancer in ever smokers were 6.2 (95% CI 3.9-10.2) for males and 2.8 (95% CI 1.7-4.4) for females. Passive smoking at home showed an overall OR of 1.8 (95% CI 1.3-2.6), similar in both genders. Attributable risk for active smoking for both genders combined, and for males and females separately, was estimated at 55, 76 and 27%, respectively. Attributable risk for passive smoking at home was 17% for females, 3.9% for males and 12% for the entire population.


CONCLUSIONS
In Mexico City smoking is attributable to a smaller proportion of lung cancer cases than in developed countries. This is explained by a lower intensity of smoking in the Mexican population.
Centro de Investigación en Salud Poblacional, Instituto Nacional de Salud Pública, México. franciscofranco@salud.gob.mx
Francisco
F
Franco-Marina
Jaime
J
Villalba Caloca
Alexander
A
Corcho-Berdugo
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D004812:Epidemiologic Methods; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000453:epidemiology / Q000209:etiology*; D008297:Male; D008800:Mexico / Q000453:epidemiology; D008875:Middle Aged; D015337:Multicenter Studies as Topic; D015999:Multivariate Analysis; D016017:Odds Ratio; D012307:Risk Factors; D012737:Sex Factors; D012907:Smoking / Q000009:adverse effects* / Q000453:epidemiology; D013997:Time Factors; D014028:Tobacco Smoke Pollution / Q000009:adverse effects*
D014028:Tobacco Smoke Pollution