Enantioselective synthesis of lobeline via nonenzymatic desymmetrization.
Lobeline has been prepared in enantiopure form via desymmetrization of lobelanidine with use of BTM, a nonenzymatic enantioselective acyl transfer catalyst.
Department of Chemistry, Washington University, Campus Box 1134, One Brookings Drive, St. Louis, Missouri 63130, USA. birman@wustl.edu
Vladimir B
VB
Birman
Hui
H
Jiang
Ximin
X
Li
D000470:Alkaloids / Q000138:chemical synthesis; D002384:Catalysis; D008120:Lobeline / Q000138:chemical synthesis*; D018722:Nicotinic Agonists / Q000138:chemical synthesis; D013237:Stereoisomerism; D014026:Nicotiana / Q000737:chemistry
D000470:Alkaloids; D018722:Nicotinic Agonists; D008120:Lobeline