[Effect of various colloidal solutions on pulmonary oxygenizing function in patients with acute lung lesion].
The effects of 6% hydroxyethyl starch and 10% albumin solution on the parameters of central hemodynamics and pulmonary extravascular water were studied in acute lung lesion. The patients were divided into 2 groups that did not significantly differ by the baseline severity of a condition (APACHE II and Murray scales). Groups 1 and 2 patients were transfused 6% hydroxyethyl starch and 10% albumin solution, respectively. The "PICCO PLUS" system was used to determine the parameters of central hemodynamics, pulmonary extravascular water, and oxygenation before and after infusion of the test colloidal solutions. Unlike 10% albumin solution, 6% hydroxyethyl starch was found to significantly increase preload parameters, without deteriorating pulmonary oxygenizing function due to the accumulation of extravascular liquid.
Krasheninnikov
S V
SV
Levit
A L
AL
Leĭderman
I N
IN
Malkova
O G
OG
D000328:Adult; D000418:Albumins / Q000008:administration & dosage / Q000627:therapeutic use*; D003102:Colloids; D005260:Female; D006801:Humans; D006895:Hydroxyethyl Starch Derivatives / Q000008:administration & dosage / Q000627:therapeutic use*; D007263:Infusions, Parenteral; D008297:Male; D010101:Oxygen Consumption; D010952:Plasma Substitutes / Q000008:administration & dosage / Q000627:therapeutic use*; D011659:Pulmonary Gas Exchange / Q000187:drug effects*; D012128:Respiratory Distress Syndrome / Q000188:drug therapy*; D012996:Solutions; D016896:Treatment Outcome
D000418:Albumins; D003102:Colloids; D006895:Hydroxyethyl Starch Derivatives; D010952:Plasma Substitutes; D012996:Solutions