Plantar keratoderma as a presenting sign of pancreatic adenocarcinoma.
A 76-year-old woman presented with a 1-year history of back pain and sudden onset of plantar keratoderma. Her serum carbohydrate antigen (CA 19.9) levels were elevated. Endoscopic radial sonographic examination led to the diagnosis of pancreatic adenocarcinoma, in a stage not detectable with helical CT yet amenable to surgical therapy. Cutaneous lesions disappeared after distal pancreatectomy.
Department of Gastroenterology, Complexo Hospitalario de Pontevedra, Avda de Montecelo sn, Pontevedra 36001, Spain.
Jose Luis
JL
Ulla
Ignacio
I
Garcia-Doval
Celia
C
Posada
Santiago
S
Soto
Carlos
C
Alvarez
Luis
L
Ledo
Enrique
E
Vazquez-Astray
D000230:Adenocarcinoma / Q000150:complications* / Q000000981:diagnostic imaging / Q000601:surgery; D000368:Aged; D003937:Diagnosis, Differential; D018450:Disease Progression; D019160:Endosonography / Q000379:methods*; D005260:Female; D006801:Humans; D007645:Keratoderma, Palmoplantar / Q000175:diagnosis / Q000209:etiology*; D010180:Pancreatectomy; D010190:Pancreatic Neoplasms / Q000150:complications* / Q000000981:diagnostic imaging / Q000601:surgery; D010257:Paraneoplastic Syndromes