Improved synthesis of O-linked, and first synthesis of S- linked, carbohydrate functionalised N-carboxyanhydrides (glycoNCAs).
An improved method for the synthesis of glycosylated N-carboxyanhydrides, which are monomers for glycopeptide synthesis, is presented.
Gibson
Matthew I
MI
IRC in Polymer Science and Technology, Department of Chemistry, University of Durham, Durham, UK DH1 3LE.
Hunt
Gregory J
GJ
Cameron
Neil R
NR
D000596:Amino Acids / Q000737:chemistry; D000812:Anhydrides / Q000737:chemistry*; D002264:Carboxylic Acids / Q000737:chemistry*; D003500:Cyclization; D006027:Glycosides / Q000138:chemical synthesis / Q000737:chemistry*; D007455:Iodine / Q000737:chemistry; D015394:Molecular Structure; D010100:Oxygen / Q000737:chemistry*; D013455:Sulfur / Q000737:chemistry*
D000596:Amino Acids; D000812:Anhydrides; D002264:Carboxylic Acids; D006027:Glycosides; D013455:Sulfur; D007455:Iodine; D010100:Oxygen