[Micrographically controlled surgery. Goals and reality].
Micrographic control of surgical margins reduces the risk of recurrence following excision of malignant neoplasms and allows for limited re-excisions of incompletely excised tumors. Several methods for checking surgical margins have been proposed. Principally, transverse sections through the entire specimen must be distinguished from longitudinal sections along all lateral margins. Transverse sections do not demonstrate the entire outer surface of the specimen. This may lead to false-negative results with subsequent recurrences. Longitudinal sections along lateral margins distort the architecture of the neoplasm and may make the diagnosis more difficult. Moreover, extensions of the neoplasm that come very close to lateral margins may be included in those sections, the consequence being false-positive results leading to unnecessary re-excisions. Regardless of the method employed, extensions of the neoplasm are not always recognizable, and, therefore, recurrences cannot be excluded.
Weyers
W
W
Zentrum für Dermatopathologie Freiburg, Engelbergerstrasse 19, 79106 Freiburg.
D001706:Biopsy / Q000639:trends*; D046169:Dermoscopy / Q000639:trends*; D005544:Forecasting; D006801:Humans; D015580:Mohs Surgery / Q000639:trends*; D012878:Skin Neoplasms / Q000473:pathology* / Q000601:surgery*; D025321:Surgery, Computer-Assisted / Q000639:trends*
J Am Acad Dermatol. 1996 Jul;35(1):82-7
8682970
J Am Acad Dermatol. 2000 Apr;42(4):696-7
10727325
J Am Acad Dermatol. 1990 Aug;23(2 Pt 1):288-94
2212126
Arch Dermatol. 2004 Aug;140(8):985-8
15313816
J Dtsch Dermatol Ges. 2003 Nov;1(11):869-75
16281577
Dermatol Monatsschr. 1982 Jul;168(7):488-93
7128883
J Dtsch Dermatol Ges. 2006 Dec;4(12):1080-4
17176417
J Am Acad Dermatol. 1998 Jul;39(1):79-97
9674401
Am J Dermatopathol. 1996 Dec;18(6):560-6
8989926
Surg Gynecol Obstet. 1986 May;162(5):449-52
3704900
Hautarzt. 1995 Sep;46(9):607-14
7591764
Hautarzt. 1984 Jun;35(6):303-7
6469635
J Am Acad Dermatol. 1995 Feb;32(2 Pt 1):233-6
7829708
Hautarzt. 1989 Jan;40(1):14-8
2646247
Arch Otolaryngol Head Neck Surg. 1997 Apr;123(4):430-3
9109793
J Am Acad Dermatol. 2004 Oct;51(4):585-91
15389195