[Investigation of the characteristics of Rh blood group of Uygur nationality in Xinjiang].
The study was to investigate the characteristics of Rh blood group of Uygur nationality in Xinjiang. 1 230 blood samples of Uygur nationality were studied by Rh serological typing, modified antiglobulin test, chloroform/trichloroethylene absorption elution test, upstream, downstream and hybrid Rhesus boxes, 10 exons of D gene, RHD(psi) pseudogene. The results showed that the frequency of RHD negative was 5.8%, and no Del type was found. The further investigation of 72 samples of RhD (-) found that ccee (57.02%) and Ccee (29.08%) phenotype as well as RHD(-)/RHD(-) genotype (94.44%) and complete deletion type of D gene exon (91.12%) were all in high frequency, no RHD(psi) pseudugene was detected. In conclusion, the Rh blood group of Uygurs nationality in Xinjiang possesses both oriental and caucasian Rh characteristics, which enriches the diversity of blood types in chinesenation.
Lan
Jiong-Cai
JC
Department of Blood Transfusion, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China. gzlanjc@tom.com
Zhou
Hua-You
HY
Bai
Xu-Hua
XH
Chen
Xiao-Ping
XP
Xing
Yan-Zhao
YZ
D044466:Asian People / Q000235:genetics*; D002681:China / Q000208:ethnology; D017353:Gene Deletion; D006801:Humans; D012204:Rh-Hr Blood-Group System / Q000235:genetics*
D012204:Rh-Hr Blood-Group System; C026410:Rho(D) antigen