title: Detection of peritoneal dissemination in gynecological malignancy: evaluation by diffusion-weighted MR imaging.
abstract: The aim of this study is to evaluate the usefulness of diffusion-weighted (DW) magnetic resonance (MR) imaging in detecting peritoneal dissemination in cases of gynecological malignancy. We retrospectively analyzed MR images obtained from 26 consecutive patients with gynecological malignancy. Peritoneal dissemination was histologically diagnosed in 15 of the 26 patients after surgery. We obtained DW images and half-Fourier single-shot turbo-spin-echo images in the abdomen and pelvis, and then generated fusion images. Coronal maximum-intensity-projection images were reconstructed from the axial source images. Reader interpretations were compared with the laparotomy findings in the surgical records. Receiver-operating characteristic (ROC) curves were used to represent the presence of peritoneal dissemination. In addition, the sensitivity and specificity were calculated. DW imaging depicted the tumors in 14 of 15 patients with peritoneal dissemination as abnormal signal intensity. ROC analysis yielded Az values of 0.974 and 0.932 for the two reviewers. The mean sensitivity and specificity were 90 and 95.5%. DW imaging plays an important role in the diagnosis and therapeutic management of patients with gynecological malignancy.
authors: Division of Radiology, Department of Pathophysiological and Therapeutic Science, Faculty of Medicine, Tottori University, 36-1, Nishi-cho, Tottori, Yonago, 683-8504, Japan. sfujii@grape.med.tottori-u.ac.jp
authors: Shinya
authors: S
authors: Fujii
authors: Eiji
authors: E
authors: Matsusue
authors: Yoshiko
authors: Y
authors: Kanasaki
authors: Yasunobu
authors: Y
authors: Kanamori
authors: Junko
authors: J
authors: Nakanishi
authors: Shuji
authors: S
authors: Sugihara
authors: Junzo
authors: J
authors: Kigawa
authors: Naoki
authors: N
authors: Terakawa
authors: Toshihide
authors: T
authors: Ogawa
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D038524:Diffusion Magnetic Resonance Imaging; D005260:Female; D006801:Humans; D007090:Image Interpretation, Computer-Assisted; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000473:pathology*; D010534:Peritoneal Neoplasms / Q000175:diagnosis* / Q000556:secondary*; D012372:ROC Curve; D012189:Retrospective Studies; D012680:Sensitivity and Specificity
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