In vivo tolerance and kinetics of a novel ocular drug delivery device.
Pijls
R T
RT
Centre for Biomaterials Research, University of Maastricht, Maastricht, The Netherlands. R.Pijls@BIOCH.unimaas.nl <R.Pijls@BIOCH.unimaas.nl>
Hanssen
H H L
HH
Nuijts
R M M A
RM
Daube
G W
GW
Koole
L H
LH
D000818:Animals; D001285:Atropine / Q000008:administration & dosage / Q000009:adverse effects / Q000493:pharmacokinetics; D003228:Conjunctiva / Q000378:metabolism*; D004285:Dogs; D016503:Drug Delivery Systems / Q000009:adverse effects / Q000295:instrumentation / Q000379:methods*; D004343:Drug Implants / Q000008:administration & dosage* / Q000009:adverse effects / Q000493:pharmacokinetics; D024841:Fluoroquinolones / Q000008:administration & dosage / Q000009:adverse effects / Q000493:pharmacokinetics; D006801:Humans; D020100:Hydrogels / Q000008:administration & dosage* / Q000737:chemistry; D008689:Methacrylates / Q000008:administration & dosage / Q000009:adverse effects / Q000737:chemistry; D009883:Ophthalmic Solutions / Q000008:administration & dosage / Q000009:adverse effects / Q000493:pharmacokinetics; D011760:Pyrrolidinones / Q000008:administration & dosage / Q000009:adverse effects / Q000737:chemistry; D013666:Tears / Q000378:metabolism
D004343:Drug Implants; D024841:Fluoroquinolones; D020100:Hydrogels; D008689:Methacrylates; D009883:Ophthalmic Solutions; D011760:Pyrrolidinones; C507250:pradofloxacin; C042670:N-vinyl-2-pyrrolidinone; D001285:Atropine; C016284:butyl methacrylate