Controversies in and challenges to our understanding of hepatitis C.
Discovered in 1989, the hepatitis C virus (HCV) continues to cause significant morbidity and mortality world-wide despite a huge research commitment to defining and understanding the virus and the disease it causes. This paper discusses a number of areas where progress in the management of the HCV have not kept pace with the scientific understanding of the HCV. It is suggested that in the fields of HCV prevention and providing access to treatment, practice falls short of what could be achieved. The role of alcohol in the pathogenesis of HCV liver injury is discussed. Discrimination against those with HCV infection and particularly those in prison settings fails to match good clinical practice. The complicated processes of sharing information between specialty groups is also discussed in an attempt to optimise knowledge dissemination in this field.
Batey
Robert G
RG
Drug and Alcohol Clinical Services, Hunter New England Area Health Services, Newcastle, New South Wales, Australia. rbate@doh.health.nsw.gov.au
D000998:Antiviral Agents / Q000627:therapeutic use; D001294:Attitude to Health; D016174:Hepacivirus / Q000276:immunology; D006526:Hepatitis C / Q000188:drug therapy / Q000209:etiology* / Q000517:prevention & control*; D006801:Humans; D033183:Interdisciplinary Communication; D014761:Viral Hepatitis Vaccines / Q000276:immunology / Q000627:therapeutic use
D000998:Antiviral Agents; D014761:Viral Hepatitis Vaccines
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