Ki-67 is expressed in multiplying forms of Schistosoma mansoni, but not in snail host tissues.
Ki-67 is a protein expressed in the nucleus of several species during cell-division, being absent during the GO resting phase of the cellular cycle. During attempts to disclose mitosis in the so-called " amebocyte-producing organ " in Biomphalaria glabrata infected with Schistosoma mansoni, the parasite multiplying forms appeared strongly marked for Ki-67, while the snail tissues were completely negative. These data are worth registering to complement general data on Ki-67, and to help future studies on the relationship of the parasite and of its intermediate host.
Silva
Tânia Maria Correia
TM
Laboratório de Patologia Experimental, Centro de Pesquisas Gonçalo Moniz, Fiocruz, Salvador, BA, 40295-001, Brasil.
Souza
Samaly Dos Santos
Sdos S
Almeida
Tais Fontoura de
TF
Andrade
Zilton A
ZA
D000818:Animals; D001700:Biomphalaria / Q000166:cytology* / Q000469:parasitology; D006434:Hemocytes / Q000737:chemistry; D006790:Host-Parasite Interactions / Q000502:physiology; D007150:Immunohistochemistry; D019394:Ki-67 Antigen / Q000378:metabolism*; D051379:Mice; D008940:Mitotic Index; D012550:Schistosoma mansoni / Q000502:physiology*; D013194:Staining and Labeling
D019394:Ki-67 Antigen