[Analysis of acute cerebral arterial thrombosis with multiple organ dysfunction syndrome].
OBJECTIVE
To investigate the incidence, case fatality and risk factors of acute cerebral arterial thrombosis complicated by multiple organ dysfunction syndrome (MODS).


METHODS
A retrospective study was conducted in 830 patients with acute cerebral arterial thrombosis, among whom 89 also developed MODS.


RESULTS
The incidence of MODS in these patients was 10.7% with case fatality of 58.4%. The presence of concurrent infection and increased number of organ involved both resulted in higher case fatality. The preceding health status, number of failing organs and score of neurologic impairment were the main fetal factors according to logistic regression analysis.


CONCLUSIONS
MODS usually occurs in two weeks after the onset of acute cerebral arterial thrombosis. Prevention of MODS involves rigorous treatment of the compromised organs and comprehensive systemic therapy in addition to the management of the primary diseases.
Jiang
Long-Yuan
LY
Departments of Emergency, Second Affiliated Hospital of Sun Yat-sen University, Guangzhou 510120, China. jly@china-em.com
Yang
Zheng-Fei
ZF
Yang
Lian-Hong
LH
D002539:Cerebral Arterial Diseases / Q000150:complications* / Q000175:diagnosis / Q000453:epidemiology / Q000401:mortality; D005260:Female; D006801:Humans; D020767:Intracranial Thrombosis / Q000150:complications* / Q000175:diagnosis / Q000453:epidemiology / Q000401:mortality; D008297:Male; D008875:Middle Aged; D009102:Multiple Organ Failure / Q000150:complications* / Q000175:diagnosis / Q000453:epidemiology / Q000401:mortality; D011379:Prognosis; D012307:Risk Factors