Pseudoachalasia of the cardia secondary to nongastrointestinal neoplasia.
A minor proportion of patients with achalasia eventually have a neoplasm and, as a consequence, pseudoachalasia is diagnosed. A neoplasm may either involve gastrointestinal junction or present a paraneoplastic effect. Over the global diagnoses of achalasia issued in 5 years of experience in our motility unit, we have found 13% (3/23 cases) of pseudoachalasia (2-4% in previous series, probably due to the fact that the population assisted was mainly composed of elderly patients). The origin of the neoplasm was bladder, prostate and metastases from epidermoid carcinoma of vocal chord. Treatment of primary neoplasm, besides classical approach (with dilatation of botulinum injection) may help in the resolution of this clinical disorder.
Ulla
Jose Luis
JL
Digestive System Service, Pontevedra Hospital Complex, Pontevedra 36001, Spain. ullarojl@terra.es
Fernandez-Salgado
Estela
E
Alvarez
Victoria
V
Ibañez
Alberto
A
Soto
Santiago
S
Carpio
Daniel
D
Vazquez-Sanluis
Javier
J
Ledo
Luis
L
Vazquez-Astray
Enrique
E
D000230:Adenocarcinoma / Q000150:complications*; D000368:Aged; D000369:Aged, 80 and over; D019274:Botulinum Toxins, Type A / Q000627:therapeutic use*; D003110:Colonic Neoplasms / Q000150:complications*; D003680:Deglutition Disorders / Q000175:diagnosis* / Q000209:etiology*; D003937:Diagnosis, Differential; D004931:Esophageal Achalasia / Q000188:drug therapy / Q000209:etiology / Q000503:physiopathology; D006801:Humans; D008297:Male; D009465:Neuromuscular Agents / Q000627:therapeutic use*; D010257:Paraneoplastic Syndromes; D014571:Urologic Neoplasms / Q000150:complications*
D009465:Neuromuscular Agents; D019274:Botulinum Toxins, Type A
Virchows Arch A Pathol Anat Histopathol. 1993;423(6):507-11
8291223
Am J Gastroenterol. 2001 Feb;96(2):373-9
11232678
J Gastrointest Surg. 2000 Nov-Dec;4(6):626-31
11307099
Histopathology. 1999 Nov;35(5):445-53
10583560
J Gastroenterol Hepatol. 1993 Nov-Dec;8(6):604-6
8280848
Br Med J. 1947 Sep 13;2(4523):405-7
20263258
Am J Gastroenterol. 1994 Nov;89(11):2014-8
7942729
Gastroenterology. 1988 Nov;95(5):1279-86
2844621
Am J Gastroenterol. 1995 Aug;90(8):1319-21
7639237
Gastroenterology. 1996 Sep;111(3):648-54
8780569
Am J Med. 1987 Mar;82(3):439-46
3548347
Dig Dis Sci. 1980 Apr;25(4):311-3
7389532
Ann Intern Med. 1978 Sep;89(3):315-8
686541
Am J Gastroenterol. 1997 Apr;92 (4):624-8
9128311
J Gastrointest Surg. 1999 Sep-Oct;3(5):456-61
10482700
Am J Surg Pathol. 2000 Aug;24(8):1153-8
10935657
Gastroenterology. 1991 Jan;100(1):137-42
1845756
Endoscopy. 1990 Jan;22(1):1-4
2407524
Ann Med Interne (Paris). 1993;144(4):303-4
8368729
Gastroenterol Hepatol. 2000 Jan;23(1):14-5
10726378
Dig Dis Sci. 1983 Mar;28(3):278-84
6825547
Dysphagia. 1994 Spring;9(2):292-6
8005010
J R Soc Med. 1988 Jul;81(7):399-402
3045313
Am J Surg Pathol. 2002 Jun;26(6):784-8
12023584
Scand J Gastroenterol. 2005 Apr;40(4):378-85
16028431
Am J Gastroenterol. 1990 Oct;85(10):1327-30
2220723
Neurology. 1998 Mar;50(3):652-7
9521251
Am J Gastroenterol. 1998 Jan;93(1):103-5
9448185