Dicationic ion-pairing agents for the mass spectrometric determination of perchlorate.
Perchlorate and other hydrophobic ions can be measured with high sensitivity and selectivity by forming a positively charged ion pair with a dicationic agent. A commercially available reagent, 1,6-bis(trimethylammonium)hexane dibromide (Br(N(CH3)3)(CH2)6(N(CH3)3)Br) allows for the determination of perchlorate by electrospray ionization mass spectrometry as the [(N(CH3)3)(CH2)6(N(CH3)3)ClO4]+ ion. Limits of detection (LODs) are better than those previously observed with custom-synthesized dicationic agents. An LOD of 20 ng/L is readily attainable with a single-quadrupole mass spectrometer.
Martinelango
P Kalyani
PK
Department of Chemistry and Biochemistry, Texas Tech University, Lubbock, Texas 79409-1061, USA.
Dasgupta
Purnendu K
PK