title: Dynamic computed tomography of the pancreas in normal dogs and in a dog with pancreatic insulinoma.
abstract: To establish optimal imaging conditions for enhanced computed tomography (CT) for canine pancreatic tumors, 10 healthy beagles were subjected to dynamic CT. This technique was then applied to a dog with suspected insulinoma. The changes in mean peak enhancement and the delay time of the aorta and pancreas were determined. In normal beagles, maximal arterial and pancreatic CT enhancement was observed at 15 +/- 2 s (795 +/- 52 Housfield unit [HU]) and 28 +/- 9 s (118 +/- 16HU) after contrast medium injection, respectively. Multiphase enhanced CT was performed in a pug with suspected insulinoma using the CT protocol defined for the normal beagles with some parameters modified; the images were acquired at the arterial (14 s after contrast medium injection), pancreatic (after 28 s), and equilibrium (after 90 s) phases; scanning was followed by exploratory laparotomy. CT images were characterized by an enhanced mass in the left pancreatic lobe at the arterial phase, during which the difference between the CT values of the mass and normal pancreas was the highest. Histopathologic diagnosis of the pancreatic mass was insulinoma. Thus, it appears that enhanced CT imaging can be used to delineate the pancreas from a pancreatic mass, and it may be helpful in deciding the need for surgery.
authors: Laboratories of Veterinary Surgery, Graduate School of Agricultural and Life Sciences, University of Tokyo, 1-1-I Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan.
authors: Toshie
authors: T
authors: Iseri
authors: Kazutaka
authors: K
authors: Yamada
authors: Kousaku
authors: K
authors: Chijiwa
authors: Ryohei
authors: R
authors: Nishimura
authors: Satoru
authors: S
authors: Matsunaga
authors: Reina
authors: R
authors: Fujiwara
authors: Nobuo
authors: N
authors: Sasaki
mesh_terms: D000818:Animals; D003287:Contrast Media / Q000008:administration & dosage; D004283:Dog Diseases / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D004285:Dogs / Q000033:anatomy & histology*; D005260:Female; D007340:Insulinoma / Q000175:diagnosis / Q000662:veterinary*; D008297:Male; D010179:Pancreas / Q000033:anatomy & histology*; D010190:Pancreatic Neoplasms / Q000175:diagnosis / Q000662:veterinary*; D014057:Tomography, X-Ray Computed / Q000662:veterinary*
chemical_list: D003287:Contrast Media