[Superior mesenteric and portal vein thrombosis in a polycythemia vera patient with JAK2 mutation].
A 47-year-old woman was admitted to our hospital in December 1994 with polycythemia. The patient's red blood cell volume was 33 ml/kg and bone marrow cytology was able to rule out other myeloproliferative diseases such as chronic myelogenous leukemia, essential thrombocytosis and myelofibrosis. The patient was diagnosed as having polycythemia vera. She had undergone only phlebotomy until 1999 when the thrombocytosis appeared, subsequent to which she was treated with oral hydroxyurea. However, in March 2006, she developed upper abdominal pain and was admitted to our hospital on March 14th, 2006. Computed tomography scan revealed thromboses in the portal and superior mesenteric veins. Anticoagulation therapy delivered intravenously via the superior mesenteric vein dramatically improved her symptoms and liver function. She is currently on anticoagulation therapy in our outpatient clinic.
Araki
Naoko
N
Fourth Department of Internal Medicine, Sapporo Medical University School of Medicine.
Takimoto
Rishu
R
Chiba
Hiroki
H
Araki
Hironobu
H
Sato
Tsutomu
T
Iyama
Satoshi
S
Hirakawa
Masahiro
M
Ono
Kaoru
K
Kawano
Yutaka
Y
Takada
Koichi
K
Miyanishi
Koji
K
Kobune
Masayoshi
M
Matsunaga
Takuya
T
Kato
Junji
J
Nakamura
Tokiko
T
Niitsu
Yoshiro
Y
D005260:Female; D006801:Humans; D053614:Janus Kinase 2 / Q000235:genetics*; D008641:Mesenteric Vascular Occlusion / Q000209:etiology*; D008642:Mesenteric Veins; D008875:Middle Aged; D017354:Point Mutation; D011087:Polycythemia Vera / Q000150:complications* / Q000235:genetics; D011169:Portal Vein; D020246:Venous Thrombosis / Q000209:etiology*
D053614:Janus Kinase 2