title: The interplay of obesity and asthma.
abstract: The relationships, interactions, and association between obesity and asthma are complex, and are active sources of hypotheses and research. An association between obesity and asthma has been reported in many studies, although considerable debate about the existence of the association and its meaning still exists. Potential associative relationships may result from genetics, immune system modifications, and mechanical mechanisms. The rising prevalence of asthma and obesity in children and adults, and the significant morbidity from both, make it imperative that clinicians recognize the importance of weight management in patients with and without asthma.
authors: Office to Advance Population Health, Department of Family and Community Medicine, Thomas Jefferson University and Hospital, 1015 Walnut Street, Suite 401, Philadelphia, PA 19107, USA. James.Plumb@jefferson.edu
authors: James
authors: J
authors: Plumb
authors: Rickie
authors: R
authors: Brawer
authors: Nancy
authors: N
authors: Brisbon
mesh_terms: D000328:Adult; D001249:Asthma / Q000453:epidemiology*; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D009765:Obesity / Q000453:epidemiology*; D015995:Prevalence
references: Hypertension. 2002 Nov;40(5):612-8
references: 12411452
references: Public Health Nutr. 1999 Sep;2(3A):369-76
references: 10610075
references: BMJ. 2002 Oct 5;325(7367):757-61
references: 12364306
references: Am J Epidemiol. 2003 Sep 1;158(5):406-15
references: 12936895
references: J Gen Intern Med. 2005 Jul;20(7):599-603
references: 16050853
references: Arch Pediatr Adolesc Med. 1998 Dec;152(12):1197-200
references: 9856429
references: Metabolism. 2002 Oct;51(10):1241-6
references: 12370841
references: J Appl Physiol (1985). 2003 Sep;95(3):938-45
references: 12794034
references: J Allergy Clin Immunol. 2005 May;115(5):897-909; quiz 910
references: 15867841
references: JAMA. 2004 Dec 8;292(22):2743-9
references: 15585734
references: Arch Intern Med. 2000 Aug 14-28;160(15):2334-9
references: 10927731
references: Arch Intern Med. 2004 Feb 9;164(3):249-58
references: 14769621
references: JAMA. 2001 Feb 21;285(7):897-905
references: 11180733
references: J Am Soc Nephrol. 2003 Jul;14(7 Suppl 2):S99-S102
references: 12819311
references: N Engl J Med. 2001 Jan 4;344(1):3-10
references: 11136953
references: J Allergy Clin Immunol. 2005 May;115(5):928-34
references: 15867847
references: J Am Board Fam Pract. 2003 Jan-Feb;16(1):14-21
references: 12583646
references: Ann Intern Med. 2001 Nov 6;135(9):825-34
references: 11694107
references: J Allergy Clin Immunol. 2005 May;115(5):911-9; quiz 920
references: 15867843
references: N Engl J Med. 2001 May 3;344(18):1343-50
references: 11333990
references: Obes Surg. 1999 Aug;9(4):385-9
references: 10484298
references: JAMA. 1999 Oct 27;282(16):1583-8
references: 10546701
references: J Allergy Clin Immunol. 2005 May;115(5):925-7
references: 15867846
references: J Gen Intern Med. 2005 Sep;20(9):814-8
references: 16117748
references: N Engl J Med. 1997 Apr 17;336(16):1117-24
references: 9099655
references: Ann Intern Med. 2003 Dec 2;139(11):933-49
references: 14644897
references: J Clin Invest. 2006 Aug;116(8):2183-2192
references: 16841093
references: Am J Epidemiol. 2002 Feb 1;155(3):198-202
references: 11821242
references: N Engl J Med. 2002 Feb 7;346(6):393-403
references: 11832527
references: J Allergy Clin Immunol. 2005 Jan;115(1):103-9
references: 15637554
references: J Allergy Clin Immunol. 2005 May;115(5):1024-8
references: 15867861