Amygdala activation in affective priming: a magnetoencephalogram study.
We employed magnetoencephalography (MEG) to examine amygdala activity during a linguistic affective priming task. The experimental design included positive and negative word pairs. Using synthetic aperture magnetometry in the analysis of MEG data, we identified a left amygdala power increase in the theta frequency range during priming involving negative words. We found that the amygdala displayed a time-dependent intensification in responsiveness to negative stimuli, specifically between 150 and 400 ms after target presentation. This study provides evidence for theta power changes in the amygdala and demonstrates that the analysis of brain oscillations provides a powerful tool to explore mechanisms implicated in emotional processing.
Garolera
Maite
M
Clinical Brain Disorders Branch, IRPP/NIMH/NIH/DHHS, Bethesda, Maryland, USA.
Coppola
Richard
R
Muñoz
Karen E
KE
Elvevåg
Brita
B
Carver
Frederick W
FW
Weinberger
Daniel R
DR
Goldberg
Terry E
TE
D000328:Adult; D000679:Amygdala / Q000502:physiology* / Q000528:radiation effects; D001931:Brain Mapping; D004644:Emotions / Q000502:physiology*; D005260:Female; D006801:Humans; D007802:Language; D015225:Magnetoencephalography; D008297:Male; D010775:Photic Stimulation; D011930:Reaction Time / Q000502:physiology; D013997:Time Factors