Chronic lymphocytic leukemia: biology and current treatment.
There has been considerable recent progress in understanding of the biology of chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL). These accomplishments have been accompanied by progressive improvement in the management of CLL and its complications. This review summarizes these changes and provides guidelines for a comprehensive approach to patient care.
Zent
Clive S
CS
Division of Hematology, Mayo Clinic College of Medicine, 200 1st Street SW, Rochester, MN 55905, USA. zent.clive@mayo.edu
Kay
Neil E
NE
D000818:Animals; D003131:Combined Modality Therapy; D004195:Disease Models, Animal; D006801:Humans; D007167:Immunotherapy; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000235:genetics / Q000473:pathology* / Q000628:therapy*
Clin Cancer Res. 2005 Nov 1;11(21):7757-63
16278397
Br J Haematol. 2001 Dec;115(4):854-61
11843819
Blood. 2006 Feb 15;107(4):1276-83
16204307
Blood. 2004 Aug 1;104(3):788-94
14996703
Br J Haematol. 2005 Jul;130(1):96-8
15982350
Blood. 2001 Jul 1;98(1):181-6
11418478
Blood. 2002 Feb 1;99(3):1023-9
11807008
Blood. 2006 Aug 1;108(3):853-61
16601244
Br J Haematol. 2005 Jan;128(2):145-52
15638848
Blood. 2001 Sep 15;98(6):1979-81
11535538
Blood. 2005 Jan 1;105(1):49-53
15138165
Hematology Am Soc Hematol Educ Program. 2005;:292-8
16304394
Blood. 2005 Oct 1;106(7):2506-12
15972449
Cancer. 1981 Jul 1;48(1):198-206
7237385
N Engl J Med. 2000 Dec 14;343(24):1750-7
11114313
Clin Cancer Res. 2001 Nov;7(11):3580-9
11705880
Blood. 2007 Jan 15;109(2):405-11
17008537
Blood. 2006 Apr 1;107(7):2889-94
16317103
Cytometry B Clin Cytom. 2003 Mar;52(1):1-12
12599176
Leukemia. 2007 May;21(5):956-64
17361231
Br J Haematol. 2005 Jul;130(1):36-42
15982342
Blood. 2003 Sep 15;102(6):2146-55
12763926
Mayo Clin Proc. 1994 Apr;69(4):323-8
8170175
Blood. 2000 May 1;95(9):2786-92
10779422
Blood. 1999 Sep 15;94(6):1840-7
10477712
Blood. 1999 Oct 15;94(8):2836-43
10515887
J Clin Oncol. 2005 Jun 20;23(18):4070-8
15767647
Blood. 2003 Jun 15;101(12):4944-51
12595313
J Clin Oncol. 2005 Jun 20;23(18):4079-88
15767648
J Clin Oncol. 2005 May 1;23(13):2971-9
15738539
Blood. 2004 Oct 15;104(8):2600-2
15205268
Blood. 2005 Jan 1;105(1):397-404
15117764
Blood. 2007 Jan 15;109(2):399-404
17003373
Blood. 1996 Jun 15;87(12):4990-7
8652811
J Clin Oncol. 2007 Mar 1;25(7):793-8
17283364
Blood. 2006 Feb 1;107(3):885-91
16219797
Blood. 1999 Sep 15;94(6):1848-54
10477713
Blood. 1975 Aug;46(2):219-34
1139039
J Clin Oncol. 2001 Mar 1;19(5):1414-20
11230486
Leuk Lymphoma. 2003 Apr;44(4):649-52
12769342
Blood. 2002 Jul 15;100(2):635-9
12091358
Semin Oncol. 1998 Feb;25(1):98-106
9482531
N Engl J Med. 2004 Aug 26;351(9):893-901
15329427
Semin Oncol. 1998 Feb;25(1):80-97
9482530
Leuk Res. 2006 Jun;30(6):707-12
16325256
Blood. 2003 May 1;101(9):3413-5
12522009
Br J Haematol. 2003 Apr;121(2):287-95
12694251
Lancet. 2004 Jan 10;363(9403):105-11
14726163
Leuk Lymphoma. 2004 Mar;45(3):507-13
15160912
Blood. 1997 Apr 1;89(7):2516-22
9116297
N Engl J Med. 2003 May 1;348(18):1764-75
12724482
Blood. 2003 Aug 1;102(3):1035-41
12676780
Semin Oncol. 1998 Feb;25(1):117-25
9482533
Leukemia. 2005 Jun;19(6):1018-24
15800671
Leukemia. 2005 Jun;19(6):1029-33
15830011
Am J Hematol. 2003 Sep;74(1):1-8
12949883
Blood. 2005 Dec 15;106(13):4389-96
16131571
J Clin Oncol. 2005 Jun 1;23(16):3819-29
15809448
Ann Intern Med. 2006 Sep 19;145(6):435-47
16983131
Cancer. 2001 Sep 1;92(5):1325-30
11571749
Blood. 2006 Feb 15;107(4):1724-30
16239425
Blood. 2004 Feb 15;103(4):1202-10
14576043
Blood. 2002 Dec 15;100(13):4609-14
12393534
N Engl J Med. 2000 Dec 28;343(26):1910-6
11136261
Blood. 2002 Aug 15;100(4):1177-84
12149195