title: Burning mouth syndrome (BMS): sialometric and sialochemical analysis and salivary protein profile.
abstract: OBJECTIVE
  The aim of the present study was to analyse the characteristics of salivary production and its composition in individuals with burning mouth syndrome (BMS).
  
  
  METHODS
  Salivary flow rate, concentrations of potassium, iron, chloride, thiocyanate, magnesium, calcium, phosphorus, glucose, total protein and urea, as well as the expression profile of salivary proteins were analysed by SDS-PAGE.
  
  
  RESULTS
  The mean salivary flow rate among control patients was lower than that of BMS patients. Chloride, phosphorus and potassium levels were elevated in patients with BMS (p = 0.041, 0.001 and 0.034, respectively). Total salivary protein concentration was reduced in individuals with BMS (p = 0.223). Analysis of the expression of salivary proteins by Coomassie blue SDS-PAGE revealed a lower expression of low molecular weight proteins in individuals with BMS compared to healthy controls.
  
  
  CONCLUSIONS
  These results indicate that the identification and characterisation of low molecular weight salivary proteins in BMS may be important in understanding BMS pathogenesis, thus contributing to its diagnosis and treatment.
authors: Faculdade de Odontologia, Universidade Federal da Paraíba-João Pessoa, Brazil/Universidade Federal da Bahia, Salvador, Brazil. adsergio@yahoo.com.br
authors: Sérgio Adriane Bezerra
authors: SA
authors: de Moura
authors: Jacira Maria Andrade
authors: JM
authors: de Sousa
authors: Dilma Ferreira
authors: DF
authors: Lima
authors: André Newton do Monte
authors: AN
authors: Negreiros
authors: Fábio de Vasconcelos
authors: Fde V
authors: Silva
authors: Lino João
authors: LJ
authors: da Costa
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002054:Burning Mouth Syndrome / Q000175:diagnosis / Q000503:physiopathology*; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012463:Saliva / Q000737:chemistry*; D012471:Salivary Proteins and Peptides / Q000032:analysis*; D012472:Salivation / Q000502:physiology
chemical_list: D012471:Salivary Proteins and Peptides