Three cases of endometrial cancer associated with "bioidentical" hormone replacement therapy.
We describe three women who developed endometrial cancer after taking "bioidentical" hormone replacement therapy (HRT) to relieve menopausal symptoms. Although pharmaceutical HRT is a well established and tested therapy, little is known about the quality control, safety and efficacy of bioidentical HRT. Women should be advised to avoid bioidentical HRT, and those who continue to use it should receive regular endometrial surveillance.
Eden
John A
JA
University of New South Wales, Sydney, NSW, Australia. j.eden@unsw.edu.au
Hacker
Neville F
NF
Fortune
Michael
M
D000368:Aged; D001688:Biological Products / Q000009:adverse effects* / Q000737:chemistry*; D004339:Drug Compounding; D016889:Endometrial Neoplasms / Q000139:chemically induced* / Q000473:pathology / Q000601:surgery; D015914:Estrogen Replacement Therapy / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008875:Middle Aged
D001688:Biological Products