Transcriptional rewiring: the proof is in the eating.
Transcriptional rewiring is an emerging evolutionary principle. Analysis of the galactose genetic pathway in Candida albicans and comparison with the classical pathway in Saccharomyces cerevisiae have revealed remarkable differences in its regulation in the two yeasts.
Rokas
Antonis
A
Vanderbilt University, Department of Biological Sciences, VU Station B 351634, Nashville, Tennessee 37235, USA. antonis.rokas@vanderbilt.edu
Hittinger
Chris Todd
CT
D002176:Candida albicans / Q000235:genetics* / Q000378:metabolism; D005656:Fungal Proteins / Q000235:genetics; D005690:Galactose / Q000378:metabolism*; D015966:Gene Expression Regulation, Fungal; D012441:Saccharomyces cerevisiae / Q000235:genetics* / Q000378:metabolism; D029701:Saccharomyces cerevisiae Proteins / Q000235:genetics; D014158:Transcription, Genetic
D005656:Fungal Proteins; D029701:Saccharomyces cerevisiae Proteins; D005690:Galactose