title: Observation of gastro-esophageal reflux by MRI: a feasibility study.
abstract: OBJECTIVE
  To evaluate the feasibility of detecting and measuring gastro-esophageal reflux (GER) with esophageal MR fluoroscopy in patients suffering from heartburn.
  
  
  METHODS
  Twenty patients with heartburn underwent esophageal MR fluoroscopy. The T1-FFE sequence was applied for MR imaging. We examined the frequency and the level of GER on MR images. Based on the MRI observations, patients were classified into four MRI grades (grade 1-4). Endoscopic findings were categorized into five grades (grade 0 to D). The overall MRI grade, Carlsson's questionnaire score, and endoscopic findings were compared.
  
  
  RESULTS
  GER was observed with MR fluoroscopy in 19 of 20 patients. GER was observed only several times in three patients, and much more frequently in the remaining 16 patients. Elevated levels of GER reached the lower, middle-to-upper esophagus, and the hypopharynx. The observed MRI grades were grade 1 = 1 patient, grade 2 = 3 patients, grade 3 = 2 patients, and grade 4 = 13 patients. There was no statistical correlation between the questionnaire score and the MRI grade. Also, there was no correlation between the grade of endoscopic findings and MRI grade. Six patients demonstrated continuous reflux on MRI did not show mucosal injury at endoscopy.
  
  
  CONCLUSIONS
  Esophageal MR fluoroscopy may be a useful diagnostic tool for GERD for its ability to show GER, even in patients with no mucosal injury, and for suggesting the cause of the reflux.
authors: Department of Radiology, Gifu University School of Medicine, Gifu, Gifu-Prefecture, Japan. manatomo@chuno.gfkosei.or.jp
authors: Tomoko
authors: T
authors: Manabe
authors: Hideaki
authors: H
authors: Kawamitsu
authors: Takanori
authors: T
authors: Higashino
authors: Daisuke
authors: D
authors: Shirasaka
authors: Nobuo
authors: N
authors: Aoyama
authors: Kazuro
authors: K
authors: Sugimura
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003287:Contrast Media; D005240:Feasibility Studies; D005260:Female; D005764:Gastroesophageal Reflux / Q000145:classification / Q000175:diagnosis*; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D011795:Surveys and Questionnaires
chemical_list: D003287:Contrast Media