Esophageal adenocarcinoma arising from Barrett's epithelium in Taiwan.
The prevalence of Barrett's esophagus (BE) in Eastern countries is rising to match the prevalence in the West. However, a corresponding trend of BE-associated adenocarcinoma has yet to be observed in Asia. Historically, adenocarcinoma complicating BE has been considered a rare event in Taiwan. In the present report, we collected three Taiwanese cases of esophageal adenocarcinoma arising from BE. The first case was a 37-year-old man with an advanced cancer that developed on pre-existing BE after a 3-year interval without endoscopic surveillance. The second case was a 63-year-old man who presented with odynophagia and was found to have an ulcerative tumor centered on the characteristic Barrett's mucosa. The final case was a 44-year-old man who presented with gradual-onset dysphagia and weight loss, without typical reflux symptom. Our report emphasizes the need for an updated epidemiologic study to determine the incidence of BE-associated adenocarcinoma in Taiwan.
Tu
Chia-Hung
CH
Department of Internal Medicine, I-Shou University Hospital, Kaohsiung, Taiwan.
Lee
Ching-Tai
CT
Perng
Daw-Shyong
DS
Chang
Chun-Chao
CC
Hsu
Chih-Hung
CH
Lee
Yi-Chia
YC
D000230:Adenocarcinoma / Q000150:complications / Q000473:pathology*; D000328:Adult; D001471:Barrett Esophagus / Q000150:complications / Q000473:pathology*; D004938:Esophageal Neoplasms / Q000150:complications / Q000473:pathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D013624:Taiwan