Response of a thymic mucoepidermoid carcinoma to combination chemotherapy with cisplatin and irinotecan: a case report.
A chemotherapeutic regimen for advanced thymic carcinoma has not yet been established. We describe a patient with advanced thymic mucoepidermoid carcinoma who achieved a complete response to combination chemotherapy with cisplatin (Randa) and irinotecan hydrochloride (Campto). A 74-year-old man was admitted to our hospital because of chest pain, general fatigue, appetite loss and weight loss. Chest computed tomography examinations revealed an anterior mediastinal tumour (5.5cmx3.5cmx9.5cm) that had invaded the subcutis through the sternum. The patient was treated with three courses of cisplatin and irinotecan hydrochloride followed by radiotherapy; he has since exhibited a complete response for 3 months.
Fuse
Etsu Tsuzuki
ET
Department of Respiratory Medicine, International Medical Center of Japan, 1-21-1 Toyama, Shinjuku-ku, Tokyo 162-8655, Japan. etfusefuse@yahoo.co.jp
Kamimura
Mitsuhiro
M
Takeda
Yuichiro
Y
Kawaishi
Makoto
M
Kimura
Sosuke
S
Niino
Hitoshi
H
Saito
Kiyoshi
K
Kobayashi
Nobuyuki
N
Kudo
Koichiro
K
D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D002166:Camptothecin / Q000008:administration & dosage / Q000031:analogs & derivatives; D018277:Carcinoma, Mucoepidermoid / Q000188:drug therapy* / Q000532:radiotherapy; D002945:Cisplatin / Q000008:administration & dosage; D003131:Combined Modality Therapy; D006801:Humans; D000077146:Irinotecan; D008297:Male; D013953:Thymus Neoplasms / Q000188:drug therapy* / Q000532:radiotherapy
D000077146:Irinotecan; D002945:Cisplatin; D002166:Camptothecin