Cognitive dysfunction with tolterodine use.
This is the first case of a 65 year old healthy woman developing de novo mental confusion during treatment with 2 mg tolterodine twice daily. It is a rare complication of therapy for overactive bladder and resolved when dosage was reduced to 1 mg, although overactive bladder symptoms were still controlled.
Salvatore
Stefano
S
Department of Obstetrics and Gynecology, University of Insubria, Del Ponte Hospital, Varese, Italy. stefanosalvatore@hotmail.com
Serati
Maurizio
M
Cardozo
Linda
L
Uccella
Stefano
S
Bolis
Pierfrancesco
P
D000368:Aged; D001559:Benzhydryl Compounds / Q000009:adverse effects*; D003072:Cognition Disorders / Q000139:chemically induced*; D003408:Cresols / Q000009:adverse effects*; D005260:Female; D006801:Humans; D010665:Phenylpropanolamine / Q000009:adverse effects*; D000068737:Tolterodine Tartrate; D053201:Urinary Bladder, Overactive / Q000188:drug therapy*
D001559:Benzhydryl Compounds; D003408:Cresols; D010665:Phenylpropanolamine; D000068737:Tolterodine Tartrate