title: Typing of the immunological system in human embryos by coelocentesis.
abstract: Coelocentesis offers a new opportunity for gaining access to the human embryos from 28 d postfertilization. However, while some studies about its biochemical composition have been reported, our knowledge about immunological pattern of this compartment is still limited. For this reason, we studied the human coelomic fluids sampled from 6.6 to 10 wk of gestation. The majority of cellular population consisted in mesenchymal/epithelial cells. In fluids sampled before 10 wk we found only a preT Cell Receptor expression and an absence or a very low frequency of B lymphocytes, T lymphocytes and NK (natural killer) antigens. These preliminary data suggest that the immunological system in human embryos could be in the ideal conditions to start a process of tolerance induction.
authors: Regional Center for Thalassemia, Haematology II with Thalassemia, V. Cervello Hospital, Palermo, Italy.
authors: Maria Concetta
authors: MC
authors: Renda
authors: George
authors: G
authors: Makrydimas
authors: Kipros H
authors: KH
authors: Nicolaides
authors: Emanuela
authors: E
authors: Fecarotta
authors: Gianfranca
authors: G
authors: Damiani
authors: Francesco
authors: F
authors: Picciotto
authors: Maria Cristina
authors: MC
authors: Jakil
authors: Aurelio
authors: A
authors: Maggio
mesh_terms: D000649:Amniocentesis; D000653:Amniotic Fluid / Q000276:immunology*; D004622:Embryo, Mammalian / Q000276:immunology*; D005260:Female; D005865:Gestational Age; D006801:Humans; D011247:Pregnancy