title: Solution and crystal conformations of myrionine, a new 8beta-alkyl-cis-decahydroquinoline of Myrioneuron nutans.
abstract: Myrionine (1), a new 8beta-alkyl-cis-decahydroquinoline, was isolated from Myrioneuron nutans. Its structure was determined by spectral methods and then confirmed by X-ray analysis and total synthesis. In solution, 1 gives rise to an N-in/N-out equilibrium. The solvent has weak influence on the N-in/N-out ratio for myrionine (1), whereas together with the anions, it plays an important role for myrionine hydrochloride (9) and hydroiodide (10). The two N-in and N-out conformations obtained separately by crystallization of 9 and 10, respectively, were analyzed by X-ray diffraction.
authors: Laboratoire de Chimie des Substances Naturelles - UMR 5154 CNRS, Muséum National d'Histoire Naturelle, 63 rue Buffon, 75005 Paris, France.
authors: Van Cuong
authors: VC
authors: Pham
authors: Akino
authors: A
authors: Jossang
authors: Angèle
authors: A
authors: Chiaroni
authors: Thierry
authors: T
authors: Sévenet
authors: Van Hung
authors: VH
authors: Nguyen
authors: Bernard
authors: B
authors: Bodo
mesh_terms: D003460:Crystallization; D018360:Crystallography, X-Ray; D009682:Magnetic Resonance Spectroscopy; D008968:Molecular Conformation; D015394:Molecular Structure; D018515:Plant Leaves / Q000737:chemistry*; D011804:Quinolines / Q000138:chemical synthesis / Q000737:chemistry* / Q000302:isolation & purification; D019666:Rubiaceae / Q000737:chemistry*; D012996:Solutions / Q000737:chemistry
chemical_list: D011804:Quinolines; D012996:Solutions; C524012:myrionine