title: Mycobacterial infections in primary immunodeficiency patients.
abstract: Primary immunodeficiencies (PID) are a diverse group of hereditary diseases leading to the impaired immune response that creates high susceptibility to mycobacterium infection. High susceptibility to mycobacterial infections of patients suffering from defects of phagocytosis and combined immunodeficiencies can be explained by predominant participation of macrophages and T lymphocytes in the specific immune response. Mycobacterium tuberculosis, Bacille Calmette-Guerin, and non-tuberculosis mycobacterium (NTM) may cause a severe disease in patients with PIDs. We report here our results of the clinical features of mycobacterium infection presentations in 36 patients with various PIDs.
authors: Russian Clinical Children's Hospital, Moscow, Russia. elizabethgalklina@yahoo.com
authors: Elizaveta
authors: E
authors: Galkina
authors: Irina
authors: I
authors: Kondratenko
authors: Andrey
authors: A
authors: Bologov
mesh_terms: D000293:Adolescent; D001500:BCG Vaccine / Q000378:metabolism; D015373:Bacterial Typing Techniques; D002648:Child; D002675:Child, Preschool; D004198:Disease Susceptibility; D005260:Female; D006801:Humans; D007107:Immune System; D007153:Immunologic Deficiency Syndromes / Q000150:complications* / Q000175:diagnosis* / Q000401:mortality; D007223:Infant; D008264:Macrophages / Q000276:immunology; D008297:Male; D009164:Mycobacterium Infections / Q000150:complications* / Q000175:diagnosis* / Q000401:mortality; D013601:T-Lymphocytes / Q000276:immunology
chemical_list: D001500:BCG Vaccine