[Anti-Titin-antibodies at the patients with myasthenic and non-myasthenic thymoma].
Serum specimens from 52 myasthenic patients with thymoma of various histological characteristics and 4 patients with thymoma without myasthenia have tested for anti-Titin-antibodies titer. It has been demonstrated that organ-specific thymoma dominated at myasthenic patients, and organ-nonspecific thymoma - at the patients without myasthenia. There was no correlation between severe clinical symptoms and the level of anti-Titin-antibodies. The titer of antibodies at the patients with organ-specific thymoma was higher that at ones with organ-nonspecific thymoma, but there was no correlation between the level of anti-Titin-antibodies and histological type of organ-specific thymoma.
Vetshev
P S
PS
Sanadze
A G
AG
Sidnev
D V
DV
Ippolitov
L I
LI
Zhivotov
V A
VA
Ablitsov
A Iu
AIu
D000328:Adult; D000368:Aged; D000912:Antibodies, Neoplasm / Q000276:immunology*; D014408:Biomarkers, Tumor / Q000276:immunology*; D064211:Connectin; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007124:Immunoenzyme Techniques; D008297:Male; D008565:Membrane Proteins / Q000276:immunology*; D008875:Middle Aged; D009124:Muscle Proteins / Q000276:immunology*; D009157:Myasthenia Gravis / Q000209:etiology / Q000276:immunology*; D011494:Protein Kinases / Q000276:immunology*; D012720:Severity of Illness Index; D013945:Thymoma / Q000150:complications / Q000276:immunology* / Q000473:pathology; D013953:Thymus Neoplasms / Q000150:complications / Q000276:immunology* / Q000473:pathology
D000912:Antibodies, Neoplasm; D014408:Biomarkers, Tumor; D064211:Connectin; D008565:Membrane Proteins; D009124:Muscle Proteins; C577285:TTN protein, human; D011494:Protein Kinases