title: CT enterography for Crohn's disease: accurate preoperative diagnostic imaging.
abstract: OBJECTIVE
  CT enterography (CTE) is a technique that provides detailed images of the small bowel by using a low Hounsfield unit oral contrast media. This study was designed to correlate CTE findings with operative findings in patients with Crohn's disease.
  
  
  METHODS
  We performed a retrospective study of all patients with Crohn's disease of the small bowel or colon, who had CTE and subsequent small bowel or colon surgery within three months after the CT examination. CTE findings of stricture, fistula, inflammatory mass, abscess, and combinations of these abnormalities were compared with operative findings. Specialist radiologists and fellowship-trained colorectal surgeons participated in the study. The Fisher's exact test or chi-squared tests were used with respect to categorical data, and the Wilcoxon's rank-sum test was used for quantitative data.
  
  
  RESULTS
  In 36 patients, the presence or absence of stricture, fistula, abscess, or inflammatory mass was correctly determined by CTE in 100, 94, 100, and 97 percent, respectively. The accuracy for stricture or fistula number was 83 and 86 percent, respectively. There were nine patients with multiple disease phenotypes identified on CTE of which eight were confirmed at surgery. CTE overestimated or underestimated the extent of disease in 11 patients (31 percent).
  
  
  CONCLUSIONS
  CTE is an accurate preoperative diagnostic imaging study for small-bowel Crohn's disease. The ability of this imaging study to detect both luminal and extraluminal pathology is a distinct advantage of CTE compared with small-bowel contrast studies.
authors: Department of Colorectal Surgery, Cleveland Clinic, 9500 Euclid Avenue, A30-262, Cleveland, Ohio 44195, USA. vogelj@ccf.org
authors: Jon
authors: J
authors: Vogel
authors: Andre
authors: A
authors: da Luz Moreira
authors: Mark
authors: M
authors: Baker
authors: Jeffery
authors: J
authors: Hammel
authors: David
authors: D
authors: Einstein
authors: Luca
authors: L
authors: Stocchi
authors: Victor
authors: V
authors: Fazio
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D003251:Constriction, Pathologic; D003424:Crohn Disease / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D007421:Intestine, Small / Q000000981:diagnostic imaging* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed / Q000379:methods*