title: Conservation and evolution of miRNA regulatory programs in plant development.
abstract: Over the past two years, microarray technologies, large-scale small RNA and whole genome sequencing projects, and data mining have provided a wealth of information about the spectrum of miRNAs and miRNA targets present in different plant species and the alga Chlamydomonas. Such studies have shown that a number of key miRNA regulatory modules for plant development are conserved throughout the plant kingdom, suggesting that these programs were crucial to the colonization of land. New genetic and biochemical studies of miRNA pathways in Arabidopsis, the spatiotemporal expression patterns of several conserved miRNAs and their targets, and the characterization of mutations in Arabidopsis and maize have begun to reveal the functions of these ancient miRNA-regulated developmental programs. In addition to these conserved miRNAs, there are many clade and species-specific miRNAs, which have evolved more recently and whose functions are currently unknown.
authors: Plant Science Institute, Department of Biology, University of Pennsylvania, Philadelphia, PA 19104-6018, USA.
authors: Matthew R
authors: MR
authors: Willmann
authors: R Scott
authors: RS
authors: Poethig
mesh_terms: D017360:Arabidopsis / Q000235:genetics* / Q000254:growth & development / Q000378:metabolism; D005075:Biological Evolution; D035683:MicroRNAs / Q000235:genetics* / Q000378:metabolism; D018749:RNA, Plant / Q000235:genetics* / Q000378:metabolism; D003313:Zea mays / Q000235:genetics* / Q000254:growth & development / Q000378:metabolism
chemical_list: D035683:MicroRNAs; D018749:RNA, Plant
references: Proc Natl Acad Sci U S A. 2005 Jun 28;102(26):9412-7
references: 15958531
references: Mol Cell. 2005 Aug 5;19(3):421-8
references: 16061187
references: Plant Cell. 2005 Aug;17(8):2186-203
references: 15994906
references: Gene. 2006 Feb 1;366(2):256-65
references: 16388920
references: Plant J. 2006 Apr;46(2):243-59
references: 16623887
references: Science. 2006 Apr 21;312(5772):436-9
references: 16627744
references: Annu Rev Plant Biol. 2006;57:19-53
references: 16669754
references: Curr Biol. 2006 May 9;16(9):927-32
references: 16682354
references: Curr Biol. 2006 May 9;16(9):933-8
references: 16682355
references: Genetics. 2006 May;173(1):373-88
references: 16489224
references: Nat Genet. 2006 Jun;38 Suppl:S31-6
references: 16736022
references: FEBS Lett. 2006 Jun 26;580(15):3753-62
references: 16780841
references: Plant Cell. 2006 Jul;18(7):1559-74
references: 16798886
references: Plant J. 2006 Jul;47(1):25-37
references: 16824179
references: Plant Cell. 2006 Aug;18(8):2051-65
references: 16861386
references: J Exp Bot. 2006;57(11):2601-12
references: 16820394
references: Development. 2006 Sep;133(18):3539-47
references: 16914499
references: Science. 2006 Sep 15;313(5793):1596-604
references: 16973872
references: Genome Res. 2006 Oct;16(10):1276-88
references: 16954541
references: Genes Dev. 2006 Nov 15;20(22):3084-8
references: 17114582
references: Genes Dev. 2006 Dec 15;20(24):3407-25
references: 17182867
references: Plant J. 2006 Nov;48(4):511-21
references: 17076803
references: Curr Opin Plant Biol. 2007 Feb;10(1):13-20
references: 17140842
references: Plant Cell. 2006 Dec;18(12):3355-69
references: 17189346
references: Nature. 2004 Mar 4;428(6978):81-4
references: 14999284
references: Nature. 2004 Mar 4;428(6978):84-8
references: 14999285
references: Science. 2004 Mar 26;303(5666):2022-5
references: 12893888
references: Nature. 2004 Apr 1;428(6982):485-6
references: 15057819
references: PLoS Biol. 2004 May;2(5):E104
references: 15024409
references: Genes Dev. 2004 May 15;18(10):1187-97
references: 15131082
references: Mol Cell. 2004 Jun 18;14(6):787-99
references: 15200956
references: Development. 2004 Jul;131(14):3357-65
references: 15226253
references: Proc Natl Acad Sci U S A. 2004 Aug 3;101(31):11511-6
references: 15272084
references: Plant Cell. 2004 Aug;16(8):2001-19
references: 15258262
references: Genome Biol. 2004;5(9):R65
references: 15345049
references: Genes Dev. 2004 Oct 1;18(19):2368-79
references: 15466488
references: Mol Cell. 2004 Oct 8;16(1):69-79
references: 15469823
references: Cell. 1993 Dec 3;75(5):843-54
references: 8252621
references: Cell. 1993 Dec 3;75(5):855-62
references: 8252622
references: Plant J. 1997 Aug;12(2):367-77
references: 9301089
references: Development. 1998 Aug;125(15):2935-42
references: 9655815
references: Development. 1999 Feb;126(3):469-81
references: 9876176
references: Gene. 1999 Sep 3;237(1):91-104
references: 10524240
references: Nat Genet. 2004 Dec;36(12):1282-90
references: 15565108
references: Nucleic Acids Res. 2005 Jan 1;33(Database issue):D637-40
references: 15608278
references: Proc Natl Acad Sci U S A. 2005 Mar 8;102(10):3691-6
references: 15738428
references: Cell. 2005 Apr 22;121(2):207-21
references: 15851028
references: Plant Cell. 2005 May;17(5):1397-411
references: 15805478
references: Dev Biol. 2005 Apr 15;280(2):504-17
references: 15882589
references: Cell Res. 2005 May;15(5):336-60
references: 15916721
references: Proc Natl Acad Sci U S A. 2005 Aug 16;102(33):11928-33
references: 16081530
references: Plant J. 2005 Sep;43(6):837-48
references: 16146523
references: Genes Dev. 2005 Sep 15;19(18):2164-75
references: 16131612
references: Plant Physiol. 2005 Aug;138(4):2145-54
references: 16040653
references: Curr Biol. 2005 Nov 22;15(22):2038-43
references: 16303564
references: Nucleic Acids Res. 2006 Jan 1;34(Database issue):D140-4
references: 16381832
references: New Phytol. 2006;169(3):469-78
references: 16411950
references: RNA. 2006 Feb;12(2):206-12
references: 16428603
references: PLoS One. 2007;2(2):e219
references: 17299599
references: Plant J. 2007 Feb;49(4):683-93
references: 17217458
references: FEBS Lett. 2007 Apr 3;581(7):1464-74
references: 17367786
references: BMC Plant Biol. 2007;7:13
references: 17359535
references: Nat Genet. 2007 Apr;39(4):544-9
references: 17369828
references: Genes Dev. 2007 Apr 1;21(7):750-5
references: 17403777
references: Nat Biotechnol. 2007 Apr;25(4):473-7
references: 17351617
references: Gene. 2007 Jun 15;395(1-2):49-61
references: 17408884
references: Genes Dev. 2007 May 15;21(10):1190-203
references: 17470535
references: Plant Cell. 2005 Jun;17(6):1658-73
references: 15849273
references: Development. 1999 Dec;126(23):5231-43
references: 10556049
references: Nature. 2000 Feb 24;403(6772):901-6
references: 10706289
references: Nature. 2001 Jun 7;411(6838):709-13
references: 11395776
references: Genes Dev. 2002 Jul 1;16(13):1616-26
references: 12101121
references: Plant Cell. 2002 Jul;14(7):1605-19
references: 12119378
references: Cell. 2002 Aug 23;110(4):513-20
references: 12202040
references: Curr Biol. 2002 Sep 3;12(17):1484-95
references: 12225663
references: Plant Physiol. 2002 Sep;130(1):6-9
references: 12226481
references: Plant Physiol. 2002 Oct;130(2):808-22
references: 12376646
references: Trends Plant Sci. 2002 Nov;7(11):487-91
references: 12417148
references: Curr Biol. 2003 Apr 29;13(9):784-9
references: 12725739
references: Nature. 2003 Sep 18;425(6955):257-63
references: 12931144
references: Curr Biol. 2003 Sep 30;13(19):1734-9
references: 14521841
references: Curr Biol. 2003 Oct 14;13(20):1768-74
references: 14561401
references: Plant Cell. 2003 Nov;15(11):2730-41
references: 14555699
references: Nucleic Acids Res. 2004 Jan 1;32(Database issue):D109-11
references: 14681370
references: Cell. 2004 Jan 23;116(2):281-97
references: 14744438
references: Proc Natl Acad Sci U S A. 2004 Jan 27;101(4):1093-8
references: 14722360
references: Curr Biol. 2004 Feb 17;14(4):346-51
references: 14972688