title: Long-term persistence of antibodies after one or two doses of MMR-vaccine.
abstract: Outbreaks of measles, mumps and rubella have occurred recently despite long-standing mass immunization with MMR. Antibody titres for measles, mumps and rubella of 160 students (17-23 years) with proof of at least one MMR-vaccine were studied according to the number of MMR-vaccines received. The proportion of subjects with positive antibody titres was significantly higher in those who received two vaccines against measles (77.1% versus 58.7%, p=0.05), mumps (67.5% versus 55.6%, p=0.009) and rubella (99.2% versus 71.4%, p=0.008). Comparable significant trends were seen for GMTs for measles and mumps. A similar non-significant trend was noted for rubella.
authors: Department of Youth Health Care, K.U. Leuven, Kapucijnenvoer 35, Block D, Box 7001, 3000 Leuven, Belgium. corinne.vandermeulen@med.kuleuven.be
authors: Corinne
authors: C
authors: Vandermeulen
authors: Roelants
authors: R
authors: Mathieu
authors: Leroux-Roels
authors: LR
authors: Geert
authors: Van Damme
authors: VD
authors: Pierre
authors: Hoppenbrouwers
authors: H
authors: Karel
mesh_terms: D000293:Adolescent; D000328:Adult; D000914:Antibodies, Viral / Q000097:blood / Q000276:immunology*; D004306:Dose-Response Relationship, Immunologic; D005260:Female; D006801:Humans; D008297:Male; D022542:Measles-Mumps-Rubella Vaccine / Q000008:administration & dosage* / Q000276:immunology*; D013997:Time Factors
chemical_list: D000914:Antibodies, Viral; D022542:Measles-Mumps-Rubella Vaccine