[Type IV-allergy due to corticosteroids. Rare and paradoxical].
METHODS
A 48-year-old woman developed a skin rash after taking glucocorticoids.


METHODS
Positive patch tests revealed type IV allergy (delayed reaction) to several glucocorticoids. In addition an eczema-like rash was produced by an oral provocation test with triamcinolone, although the patch test for this drug had been negative.


METHODS
We recommended avoidance of the positively-tested corticosteroids and issued a corresponding allergy pass.


CONCLUSIONS
Type IV allergy to glucocorticoids is rare but should be considered whenever patients develop a skin rash after the use of corticosteroids.
Plaza
T
T
Klinik für Dermatologie und Allergologie, Zentrum für Hautkrankheiten, Klinikum Stuttgart, Stuttgart, Germany. t.plaza@kbc-intern.de
Nist
G
G
von den Driesch
P
P
D004342:Drug Hypersensitivity / Q000209:etiology* / Q000517:prevention & control*; D005260:Female; D005938:Glucocorticoids / Q000009:adverse effects*; D006801:Humans; D006968:Hypersensitivity, Delayed / Q000139:chemically induced* / Q000517:prevention & control*; D008875:Middle Aged; D011241:Prednisone / Q000009:adverse effects*; D012882:Skin Tests
D005938:Glucocorticoids; D011241:Prednisone