title: Drug-induced acute myopia following chlorthalidone treatment.
abstract: We report a case of sudden loss of vision due to the development of acute myopia after the intake of chlorthalidone used for treating systemic hypertension. Clinically this was associated with ciliary spasm, shallow peripheral choroidal effusion and retinal striae at the macula with increase in macular thickness seen on optical coherence tomography. All these findings were reversed completely once the drug was discontinued. Development of acute myopia should be kept in mind as an adverse effect of a commonly used antihypertensive drug, namely chlorthalidone.
authors: Giridhar Eye Institute, 28/2576 A, Ponneth Temple Road. Kadavanthra, Cochin - 682 020, Kerala, India. girieye@vsnl.com
authors: G
authors: G
authors: Mahesh
authors: A
authors: A
authors: Giridhar
authors: S J
authors: SJ
authors: Saikumar
authors: Sachin
authors: S
authors: Fegde
mesh_terms: D000208:Acute Disease; D000328:Adult; D002752:Chlorthalidone / Q000009:adverse effects* / Q000627:therapeutic use; D004232:Diuretics / Q000009:adverse effects* / Q000627:therapeutic use; D005500:Follow-Up Studies; D006801:Humans; D006973:Hypertension / Q000188:drug therapy; D008297:Male; D009216:Myopia / Q000139:chemically induced*; D041623:Tomography, Optical Coherence; D014792:Visual Acuity / Q000187:drug effects
chemical_list: D004232:Diuretics; D002752:Chlorthalidone
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