Supramolecular interactions between beta-cyclodextrin and hydrophobically end-capped poly(ethylene glycol)s: a quartz crystal microbalance study.
In this study, the supramolecular interactions occurring between beta-cyclodextrin-based surfaces and macromolecular chains modified at one end with naphthyl, adamantyl, or phenyladamantyl hydrophobic groups were investigated by means of a quartz crystal microbalance. beta-Cyclodextrin-functionalized gold electrodes were obtained through the amide-coupling reaction between mono-6-deoxy-6-amino-beta-cyclodextrin and 11-mercaptoundecanoic acid self-assembled monolayer allowing the reproducible preparation of densely grafted surfaces with host properties. The interaction data obtained for the three different modified poly(ethylene glycol)s are in good agreement with our previous studies performed by high performance liquid chromatography and surface plasmon resonance. This evidences that the driving force for the supramolecular interaction is based on the inclusion of the hydrophobic terminal group of the chains within the cyclodextrin cavities. The reversibility of the inclusion process was proven through the regeneration of the original host properties of the sensing surfaces using sodium dodecylsulfate as a competitor for the desorption of the poly(ethylene glycol) chains.
Kham
Khémara
K
Institut Chimie et Matériaux Paris Est-Equipe Systèmes Polymères Complexes, CNRS-Université Paris 12 UMR 7182, 2-8 rue Henri Dunant, 94320 Thiais, France.
Guerrouache
Mohamed
M
Carbonnier
Benjamin
B
Lazerges
Mathieu
M
Perrot
Hubert
H
Millot
Marie-Claude
MC
D004566:Electrodes; D006046:Gold; D057927:Hydrophobic and Hydrophilic Interactions; D046911:Macromolecular Substances; D011092:Polyethylene Glycols / Q000737:chemistry*; D011791:Quartz; D020349:Surface Plasmon Resonance; D013499:Surface Properties; D047392:beta-Cyclodextrins / Q000737:chemistry*
D046911:Macromolecular Substances; D047392:beta-Cyclodextrins; D011791:Quartz; D011092:Polyethylene Glycols; D006046:Gold; C031215:betadex