In vitro activity of micafungin combined with itraconazole against Candida spp.
The in vitro activity of the combination micafungin + itraconazole was evaluated against 105 strains of six species of Candida. The highest percentage of synergy was obtained against Candida albicans (50%) and the lowest against Candida tropicalis (0%).
Mariné
Marçal
M
Unitat de Microbiologia, Facultat de Medicina i Ciències de la Salut, Universitat Rovira i Virgili, Carrer Sant Llorenç 21, 43201 Reus, Spain.
Serena
Carolina
C
Pastor
Javier
J
Quindós
Guillermo
G
Carrillo
A Javier
AJ
Guarro
Josep
J
D000935:Antifungal Agents / Q000494:pharmacology*; D002175:Candida / Q000187:drug effects*; D004357:Drug Synergism; D054714:Echinocandins / Q000494:pharmacology*; D017964:Itraconazole / Q000494:pharmacology*; D055666:Lipopeptides; D008074:Lipoproteins / Q000494:pharmacology*; D000077551:Micafungin; D008826:Microbial Sensitivity Tests
D000935:Antifungal Agents; D054714:Echinocandins; D055666:Lipopeptides; D008074:Lipoproteins; D017964:Itraconazole; D000077551:Micafungin