Nonenzymatic oxidative steps accompanying action of the cytochrome P450 enzymes StaP and RebP in the biosynthesis of staurosporine and rebeccamycin.
Howard-Jones
Annaleise R
AR
Department of Biological Chemistry & Molecular Pharmacology, Harvard Medical School, 240 Longwood Avenue, Boston, Massachusetts 02115, USA.
Walsh
Christopher T
CT
D002227:Carbazoles / Q000378:metabolism*; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism*; D007211:Indoles / Q000378:metabolism*; D015394:Molecular Structure; D010084:Oxidation-Reduction; D019311:Staurosporine / Q000096:biosynthesis*
D002227:Carbazoles; D007211:Indoles; D003577:Cytochrome P-450 Enzyme System; C053339:rebeccamycin; D019311:Staurosporine