title: Incidence, risk factors, and pathogenesis of second malignancies in patients with non-Hodgkin lymphoma.
abstract: Most Non-Hodgkin's Lymphoma patients will survive their diagnosis. High dose chemotherapy and autologous stem cell transplantation, and radiation therapy have all been implicated as risk factors to secondary cancer development. Herein, we will review the molecular biology, examine the epidemiologic findings, discuss the impact of both chemotherapy and radiotherapy, and focus on the special populations of pediatrics and high dose chemotherapy and autologous stem cell transplantation with regard to secondary cancer development.
authors: Huntsman Cancer Hospital, University of Utah, UT 84112-5560, USA. Jonathan.Tward@hci.utah.edu
authors: Jonathan
authors: J
authors: Tward
authors: Martha
authors: M
authors: Glenn
authors: Michael
authors: M
authors: Pulsipher
authors: Phillip
authors: P
authors: Barnette
authors: David
authors: D
authors: Gaffney
mesh_terms: D000970:Antineoplastic Agents / Q000009:adverse effects; D018380:Hematopoietic Stem Cell Transplantation / Q000009:adverse effects; D006801:Humans; D015994:Incidence; D008228:Lymphoma, Non-Hodgkin / Q000473:pathology* / Q000628:therapy; D016609:Neoplasms, Second Primary / Q000453:epidemiology* / Q000209:etiology*; D011878:Radiotherapy / Q000009:adverse effects; D012307:Risk Factors
chemical_list: D000970:Antineoplastic Agents