title: Arabidopsis thaliana inositol 1,3,4-trisphosphate 5/6-kinase 4 (AtITPK4) is an outlier to a family of ATP-grasp fold proteins from Arabidopsis.
abstract: The Arabidopsis genome encodes a family of inositol 1,3,4-trisphosphate 5/6-kinases which form a subgroup of a larger group of ATP-grasp fold proteins. An analysis of the inositol 1,3,4-trisphosphate 5/6-kinase family might, ultimately, be best rewarded by detailed comparison of related enzymes in a single genome. The enzyme encoded by At2G43980, AtITPK4; is an outlier to its family. At2G43980 is expressed in male and female organs of young and mature flowers. AtITPK4 differs from other family members in that it does not display inositol 3,4,5,6-tetrakisphosphate 1-kinase activity; rather, it displays inositol 1,4,5,6-tetrakisphosphate and inositol 1,3,4,5-tetrakisphosphate isomerase activity.
authors: School of Biological Sciences, University of East Anglia, Earlham Road, Norwich, Norfolk, UK.
authors: Dylan
authors: D
authors: Sweetman
authors: Ioanna
authors: I
authors: Stavridou
authors: Sue
authors: S
authors: Johnson
authors: Porntip
authors: P
authors: Green
authors: Samuel E K
authors: SE
authors: Caddick
authors: Charles A
authors: CA
authors: Brearley
mesh_terms: D000255:Adenosine Triphosphate / Q000378:metabolism*; D000595:Amino Acid Sequence; D017360:Arabidopsis / Q000201:enzymology* / Q000235:genetics; D029681:Arabidopsis Proteins / Q000737:chemistry* / Q000235:genetics / Q000378:metabolism*; D035264:Flowers / Q000166:cytology / Q000201:enzymology; D020869:Gene Expression Profiling; D018506:Gene Expression Regulation, Plant; D005966:Glucuronidase / Q000378:metabolism; D017403:In Situ Hybridization; D007700:Kinetics; D008969:Molecular Sequence Data; D017853:Phosphotransferases (Alcohol Group Acceptor) / Q000737:chemistry* / Q000235:genetics / Q000378:metabolism*; D011401:Promoter Regions, Genetic / Q000235:genetics; D017433:Protein Structure, Secondary; D011994:Recombinant Proteins / Q000378:metabolism; D017386:Sequence Homology, Amino Acid; D013379:Substrate Specificity
chemical_list: D029681:Arabidopsis Proteins; D011994:Recombinant Proteins; D000255:Adenosine Triphosphate; C523492:inositol 1,3,4-trisphosphate 5-6-kinase 4, Arabidopsis; D017853:Phosphotransferases (Alcohol Group Acceptor); D005966:Glucuronidase