Sleep and EEG spectra in rats recorded via telemetry during surgical recovery.
OBJECTIVE
To determine sleep and EEG spectra in rats during surgical recovery.


METHODS
Sleep, activity, and EEG spectral power were examined in rats via telemetry on days 1, 2, 3, 7, 14, and 15 after implantation surgery.


RESULTS
NREM sleep and total sleep were increased on days 1 and 2 compared to later days. REM sleep was decreased on days 2 and 3 compared to days 14 and 15, and activity was decreased on days 1 and 2 compared to later days. EEG power (0.5-5 Hz for NREM and wakefulness, and 5.5-10 Hz for REM and wakefulness) was increased on days 1-3 compared to days 7, 14, and 15.


CONCLUSIONS
The results are discussed in terms of their implications for post-surgery stabilization of sleep and potential relevance for sleep after injury.
Tang
Xiangdong
X
Sleep Research Laboratory, Department of Pathology and Anatomy, Eastern Virginia Medical School, Norfolk, VA 23501, USA. tangx@evms.edu
Yang
Linghui
L
Sanford
Larry D
LD
D000762:Anesthesia Recovery Period; D000818:Animals; D002540:Cerebral Cortex / Q000503:physiopathology*; D002940:Circadian Rhythm / Q000502:physiology; D004567:Electrodes, Implanted; D004569:Electroencephalography; D005583:Fourier Analysis; D008297:Male; D009043:Motor Activity / Q000502:physiology; D017286:Polysomnography; D011184:Postoperative Period; D051381:Rats; D017208:Rats, Wistar; D012815:Signal Processing, Computer-Assisted; D012894:Sleep Stages / Q000502:physiology*; D013826:Theta Rhythm; D014851:Wakefulness / Q000502:physiology
Brain Res. 2003 Dec 12;993(1-2):164-71
14642842
Behav Brain Res. 1983 Aug;9(2):151-63
6882522
Crit Rev Immunol. 1994;14(3-4):355-79
7755878
Proc Soc Exp Biol Med. 1995 Dec;210(3):242-52
8539262
Front Biosci. 2003 May 1;8:d520-50
12700031
Brain Res. 2006 Apr 21;1084(1):80-8
16546144
Anesth Analg. 2001 May;92(5):1232-6
11323352
Contemp Top Lab Anim Sci. 2000 Nov;39(6):18-23
11487247
Sleep. 2002 Sep 15;25(6):691-9
12224849
Comp Med. 2005 Feb;55(1):37-44
15766208