title: Hospitalization-based major comorbidity of inflammatory bowel disease in Canada.
abstract: OBJECTIVE
  To define the patterns of hospitalization for known major comorbidities associated with inflammatory bowel disease (IBD) in Canada.
  
  
  METHODS
  The data source was the Statistics Canada Health Person Oriented Information hospital database (1994/1995 to 2003/2004). The number of stays for a diagnosis of Crohn's disease or ulcerative colitis by the International Classification of Diseases, ninth edition, codes 555 or 556, or the International Classification of Diseases, 10th edition, Canadian Enhancement, codes K50 or K51, was extracted. Age- and sex-specific and age-adjusted rates of hospitalization for selected IBD-related comorbidities were assessed.
  
  
  RESULTS
  Rates of Hodgkin's disease and non-Hodgkin's lymphoma were low in the hospitalized IBD population. Rates for colon cancer, rectal cancer, pulmonary emboli and deep venous thromboembolism were generally higher among IBD patients younger than 50 years of age compared with the non-IBD hospitalized population.
  
  
  CONCLUSIONS
  IBD was associated with life-threatening comorbidities such as venous thromboembolic disease and colon cancer among persons younger than 50 years of age to a greater extent than the general hospitalized population. Recent secular trends in rates of non-Hodgkin's lymphomas will need to be followed to determine whether the whole population, including IBD patients who receive immunomodulating therapies, are at increased risk.
authors: Department of Internal Medicine, University of Manitoba Inflammatory Bowel Disease Clinical and Research Centre, Winnipeg, Canada. cbernst@cc.umanitoba.ca
authors: Charles N
authors: CN
authors: Bernstein
authors: Alice
authors: A
authors: Nabalamba
mesh_terms: D002170:Canada / Q000453:epidemiology; D003110:Colonic Neoplasms / Q000453:epidemiology; D015897:Comorbidity; D005260:Female; D006689:Hodgkin Disease / Q000453:epidemiology; D006760:Hospitalization / Q000706:statistics & numerical data*; D006801:Humans; D015212:Inflammatory Bowel Diseases / Q000453:epidemiology*; D038801:International Classification of Diseases; D008228:Lymphoma, Non-Hodgkin / Q000453:epidemiology; D008297:Male; D008499:Medical Records; D008875:Middle Aged; D011655:Pulmonary Embolism / Q000453:epidemiology; D012004:Rectal Neoplasms / Q000453:epidemiology; D012189:Retrospective Studies; D013923:Thromboembolism / Q000453:epidemiology
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