title: Enteric glial cells and their role in gastrointestinal motor abnormalities: introducing the neuro-gliopathies.
abstract: The role of enteric glial cells has somewhat changed from that of mere mechanical support elements, gluing together the various components of the enteric nervous system, to that of active participants in the complex interrelationships of the gut motor and inflammatory events. Due to their multiple functions, spanning from supporting elements in the myenteric plexuses to neurotransmitters, to neuronal homeostasis, to antigen presenting cells, this cell population has probably more intriguing abilities than previously thought. Recently, some evidence has been accumulating that shows how these cells may be involved in the pathophysiological aspects of some diseases. This review will deal with the properties of the enteric glial cells more strictly related to gastrointestinal motor function and the human pathological conditions in which these cells may play a role, suggesting the possibility of enteric neuro-gliopathies.
authors: Gabrio
authors: G
authors: Bassotti
authors: Vincenzo
authors: V
authors: Villanacci
authors: Simona
authors: S
authors: Fisogni
authors: Elisa
authors: E
authors: Rossi
authors: Paola
authors: P
authors: Baronio
authors: Carlo
authors: C
authors: Clerici
authors: Christoph A
authors: CA
authors: Maurer
authors: Gieri
authors: G
authors: Cathomas
authors: Elisabetta
authors: E
authors: Antonelli
mesh_terms: D000818:Animals; D004195:Disease Models, Animal; D017615:Enteric Nervous System / Q000166:cytology / Q000502:physiology*; D005767:Gastrointestinal Diseases / Q000503:physiopathology; D005769:Gastrointestinal Motility / Q000502:physiology*; D041981:Gastrointestinal Tract / Q000294:innervation / Q000502:physiology; D006801:Humans; D009457:Neuroglia / Q000166:cytology / Q000502:physiology*
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