title: [Metastatic lesions to the pancreas. When is resection reasonable?].
abstract: BACKGROUND
  The significance of pancreatic resection for pancreatic metastatic lesions has not yet been sufficiently investigated. A retrospective analysis of patients undergoing pancreatic resections for pancreatic metastases was conducted.
  
  
  METHODS
  Twenty patients were resected due to metastatic lesions to the pancreas. Histopathological findings were: renal cell carcinoma (n=9), colon carcinoma (n=1), malignant schwannoma (n=2), leiomyosarcoma (n=2), teratocarcinoma (n=1), adenocarcinoma of the oesophagus (n=1), gallbladder carcinoma (n=1), malignant melanoma (n=1), gastrointestinal stromal tumor (n=1), and spindle cell tumor (n=1). Operative procedures were standard pancreaticoduodenectomy (n=6), pylorus-preserving pancreaticoduodenectomy (n=6), and distal pancreatectomy (n=8).
  
  
  RESULTS
  The overall 5-year survival rate was 61%, for patients with renal cell carcinoma 100%.
  
  
  CONCLUSIONS
  Pancreatic metastasectomy is a reasonable therapeutic option in suited patients. Patients with pancreatic metastases of renal cell carcinoma achieved excellent prognoses after radical resection.
authors: Klinik für Allgemein-, Viszeral- und Transplantationschirurgie, Charité - Universitätsmedizin Berlin, Campus Virchow-Klinikum, Augustenburger Platz 1, 13353, Berlin. marcus.bahra@charite.de
authors: M
authors: M
authors: Bahra
authors: D
authors: D
authors: Jacob
authors: J M
authors: JM
authors: Langrehr
authors: M
authors: M
authors: Glanemann
authors: G
authors: G
authors: Schumacher
authors: E
authors: E
authors: Lopez-Hänninen
authors: P
authors: P
authors: Neuhaus
mesh_terms: D000368:Aged; D017024:Chemotherapy, Adjuvant; D003131:Combined Modality Therapy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008197:Lymph Node Excision; D008297:Male; D008875:Middle Aged; D010166:Palliative Care; D010180:Pancreatectomy; D010190:Pancreatic Neoplasms / Q000175:diagnosis / Q000401:mortality / Q000556:secondary* / Q000601:surgery*; D015996:Survival Rate
references: Arch Surg. 1998 Apr;133(4):413-7; discussion 418-9
references: 9565122
references: J Am Coll Surg. 2003 Aug;197(2):233-41; discussion 241-2
references: 12892803
references: Virchows Arch. 2004 Jun;444(6):527-35
references: 15057558
references: Br J Surg. 1995 Jul;82(7):975-9
references: 7648124
references: Cancer. 2000 Sep 1;89(5):1076-88
references: 10964338
references: Chirurg. 1994 Apr;65(4):232-40
references: 7912664
references: Hepatogastroenterology. 2000 Mar-Apr;47(32):540-4
references: 10791233
references: Ann Surg. 2002 Aug;236(2):137-48
references: 12170018
references: Radiographics. 1998 Mar-Apr;18(2):369-78
references: 9536484
references: World J Surg. 2007 Mar;31(3):511-21
references: 17308854
references: Acta Cytol. 1992 Jul-Aug;36(4):471-6
references: 1636336
references: J Surg Oncol. 2003 Jul;83(3):161-6; discussion 166
references: 12827684
references: JOP. 2005 Jul 08;6(4):339-43
references: 16006684
references: Pathol Int. 2001 Sep;51(9):686-90
references: 11696171
references: Int J Pancreatol. 1996 Apr;19(2):145-53
references: 8723558
references: World J Surg. 2006 Aug;30(8):1536-42
references: 16847716
references: Surg Gynecol Obstet. 1989 Apr;168(4):345-7
references: 2928909
references: Pancreas. 1993 Mar;8(2):276-8
references: 8460104
references: Cancer. 1950 Jan;3(1):74-85
references: 15405683