Nonalcoholic fatty liver disease as a feature of the metabolic syndrome.
The main criteria of the metabolic syndrome are obesity, insulin resistance and disturbed lipid metabolism. The same disturbances are regarded to be involved into the pathomechanism of nonalcoholic fatty liver disease which is shown by epidemiological studies and animal models. Thus NAFLD can be regarded a specific feature of the metabolic syndrome and it should be looked for in high risk populations.
Socha
Piotr
P
Department of Gastroenterology, Hepatology and Immunology The Children's Memorial Health Institute Poland, 04-730 Warsaw. p.socha@czd.pl
Wierzbicka
Aldona
A
Neuhoff-Murawska
Joanna
J
Włodarek
Dariusz
D
Podleśny
Jerzy
J
Socha
Jerzy
J
D000818:Animals; D015992:Body Mass Index; D003927:Diet, Diabetic / Q000592:standards; D018752:Diet, Fat-Restricted / Q000592:standards; D016021:Epidemiologic Studies; D005234:Fatty Liver / Q000178:diet therapy / Q000209:etiology* / Q000503:physiopathology*; D006801:Humans; D006946:Hyperinsulinism / Q000150:complications / Q000503:physiopathology; D007004:Hypoglycemic Agents / Q000627:therapeutic use; D007333:Insulin Resistance; D052439:Lipid Metabolism Disorders / Q000150:complications* / Q000503:physiopathology; D024821:Metabolic Syndrome / Q000150:complications* / Q000503:physiopathology*; D009765:Obesity / Q000150:complications / Q000503:physiopathology; D012307:Risk Factors; D013577:Syndrome; D015431:Weight Loss
D007004:Hypoglycemic Agents