title: Epicoccins A-D, epipolythiodioxopiperazines from a Cordyceps-colonizing isolate of Epicoccum nigrum.
abstract: Epicoccins A-D (1-4), four unique epipolythiodioxopiperazines possessing unusual sulfur bridges, have been isolated from cultures of a Cordyceps-colonizing isolate of Epicoccum nigrum. The structures of these compounds were determined mainly by analysis of their NMR spectroscopic data. The relative and absolute configuration of epicoccin A (1) was established by single-crystal X-ray diffraction analysis. Epicoccin A (1) showed modest antimicrobial activity.
authors: Key Laboratory of Systematic Mycology and Lichenology, and Center for Bio-Energy and Industrial Microbiology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, 100080, People's Republic of China.
authors: Yonggang
authors: Y
authors: Zhang
authors: Shuchun
authors: S
authors: Liu
authors: Yongsheng
authors: Y
authors: Che
authors: Xingzhong
authors: X
authors: Liu
mesh_terms: D000890:Anti-Infective Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D001203:Ascomycota / Q000737:chemistry*; D032661:Cordyceps / Q000737:chemistry; D018360:Crystallography, X-Ray; D008968:Molecular Conformation; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D010879:Piperazines / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D018609:Tibet
chemical_list: D000890:Anti-Infective Agents; D010879:Piperazines