title: Designing compound libraries targeting GPCRs.
abstract: The design of compound libraries targeting GPCRs is of primary interest in pharmaceutical research because of their important role as signaling receptors and the herewith linked dominant place in the discovery portfolios. In the present symposium chapter, we outline GPCR compound library design strategies recently followed by our group and discuss them in a more general context.
authors: Novartis Institutes for BioMedical Research, Discovery Tehnologies, Lichtstrasse 35, 4056 Basel, Switzerland. edgar.jacoby@novartis.com
authors: E
authors: E
authors: Jacoby
mesh_terms: D000818:Animals; D020650:Combinatorial Chemistry Techniques; D015195:Drug Design; D006801:Humans; D008024:Ligands; D008956:Models, Chemical; D019151:Peptide Library; D043562:Receptors, G-Protein-Coupled / Q000737:chemistry* / Q000378:metabolism; D013329:Structure-Activity Relationship
chemical_list: D008024:Ligands; D019151:Peptide Library; D043562:Receptors, G-Protein-Coupled