Adaptive bayesian iterative transmission reconstruction for attenuation correction in myocardial perfusion imaging with SPECT/slow-rotation low-output CT systems.
OBJECTIVE
SPECT/slow-rotation low-output CT systems can produce streak artifacts in filtered backprojection (FBP) attenuation maps, impacting attenuation correction (AC) in myocardial perfusion imaging. This paper presents an adaptive Bayesian iterative transmission reconstruction (ABITR) algorithm for more accurate AC.


METHODS
In each iteration, ABITR calculated a three-dimensional prior containing the pixels with attenuation coefficients similar to water, then used it to encourage these pixels to the water value. ABITR was tested with a cardiac phantom and 4 normal patients acquired by a GE Millennium VG/Hawkeye system.


RESULTS
FBP AC and ABITR AC produced similar phantom results. For the patients, streak artifacts were observed in the FBP and ordered-subsets expectation-maximization (OSEM) maps but not in the ABITR maps, and ABITR AC produced more uniform images than FBP AC and OSEM AC.


CONCLUSIONS
ABITR can improve the quality of the attenuation map, producing more uniform images for normal studies.
Chen
Ji
J
Department of Radiology, School of Medicine, Emory University, 1364 Clifton Road, Atlanta, GA 30322, USA.
Garcia
Ernest V
EV
Folks
Russell D
RD
Peretz
Aharon
A
Galt
James R
JR
J Nucl Med. 2003 Feb;44(2):291-315
12571222
J Nucl Cardiol. 2002 Mar-Apr;9(2):183-7
11986563
J Nucl Med. 1989 Apr;30(4):497-507
2786944
J Nucl Cardiol. 2002 Jan-Feb;9(1):135-43
11845140
IEEE Trans Med Imaging. 2001 Apr;20(4):342-53
11370901
J Nucl Cardiol. 2002 Jan-Feb;9(1):52-62
11845130
J Nucl Med. 1984 Aug;25(8):893-900
6611390
J Nucl Cardiol. 2002 Jul-Aug;9(4):361-76
12161711
J Nucl Cardiol. 1995 Nov-Dec;2(6):513-24
9420834
Am J Cardiol. 1990 Oct 16;66(13):23E-31E
2145742
J Nucl Cardiol. 2001 Jan-Feb;8(1):G5-G58
11182716
J Nucl Cardiol. 2000 Sep-Oct;7(5):414-25
11083189
IEEE Trans Med Imaging. 2000 May;19(5):548-55
11021698
Circulation. 1999 Jun 1;99(21):2742-9
10351967