title: [Effects of volatile organic compounds on brain amino acid neurotransmitter in mice].
abstract: OBJECTIVE
  Study adverse effects of volatile organic compounds volatile organic compounds (VOCs) on brain amino acid neurotransmitter in mice.
  
  
  METHODS
  Four groups of mouse were respectively exposed to 0, low, middle and high concentration of VOCs for two hours every day for 30 days. The content of brain amino acid neurotransmitter was determined.
  
  
  RESULTS
  The result showed that the content of Glu and ASP in brain of VOCs -exposed mouse decreased and GABA and Gly increased compared with that of control.
  
  
  CONCLUSIONS
  The memory impair in mice induced by exposing VOCs may relate to the chang of content of amino acid neurotransmitter.
authors: School of Public Health, Fudan University, Shanghai 200032, China.
authors: Huanzhu
authors: H
authors: Zhang
authors: Weimin
authors: W
authors: Song
mesh_terms: D000596:Amino Acids / Q000378:metabolism*; D000818:Animals; D001224:Aspartic Acid / Q000378:metabolism; D001921:Brain / Q000378:metabolism*; D001923:Brain Chemistry; D005260:Female; D018698:Glutamic Acid / Q000378:metabolism; D008297:Male; D051379:Mice; D018377:Neurotransmitter Agents / Q000378:metabolism*; D011897:Random Allocation; D055549:Volatile Organic Compounds / Q000633:toxicity*; D005680:gamma-Aminobutyric Acid / Q000378:metabolism
chemical_list: D000596:Amino Acids; D018377:Neurotransmitter Agents; D055549:Volatile Organic Compounds; D001224:Aspartic Acid; D018698:Glutamic Acid; D005680:gamma-Aminobutyric Acid