title: Using the Autism Diagnostic Interview-Revised and the Autism Diagnostic Observation Schedule with young children with developmental delay: evaluating diagnostic validity.
abstract: Few studies have focused on the validity of the ADI-R and ADOS in the assessment of preschool children with developmental delay. This study aimed to evaluate the diagnostic validity of the ADI-R and the ADOS in young children. Two-hundred and nine children aged 20-55 months participated in the study, 120 of whom received a diagnosis of autism. ADI-R and ADOS diagnostic classifications were compared to consensus clinical diagnoses. Children with a clinical diagnosis of autism scored significantly higher on all algorithm domains of the ADI-R and ADOS. The ADOS performed better than the ADI-R in comparison to consensus clinical diagnosis. Characteristics of the ADI-R and ADOS false positive and false negative cases are explored. Further research is recommended in terms of examining which items of the ADI-R best predict a diagnosis of autism for very young children with developmental problems.
authors: Centre for Developmental Psychiatry and Psychology, School of Psychology, Psychiatry and Psychological Medicine, Monash University, 246 Clayton Road, Clayton, Victoria, Australia. kylie.gray@med.monash.edu.au
authors: Kylie M
authors: KM
authors: Gray
authors: Bruce J
authors: BJ
authors: Tonge
authors: Deborah J
authors: DJ
authors: Sweeney
mesh_terms: D001321:Autistic Disorder / Q000175:diagnosis* / Q000453:epidemiology*; D002675:Child, Preschool; D002658:Developmental Disabilities / Q000175:diagnosis* / Q000453:epidemiology*; D005260:Female; D006801:Humans; D007223:Infant; D007406:Interview, Psychological; D008297:Male; D019370:Observation; D015203:Reproducibility of Results; D012720:Severity of Illness Index
references: J Autism Dev Disord. 2000 Jun;30(3):205-23
references: 11055457
references: Psychopathology. 2001 Jul-Aug;34(4):187-91
references: 11549928
references: Eur Child Adolesc Psychiatry. 2001 Dec;10(4):248-55
references: 11794550
references: J Autism Dev Disord. 1997 Oct;27(5):501-17
references: 9403369
references: Arch Gen Psychiatry. 2006 Jun;63(6):694-701
references: 16754843
references: J Autism Dev Disord. 1994 Oct;24(5):659-85
references: 7814313
references: Autism. 2002 Jun;6(2):159-68
references: 12083282
references: J Autism Dev Disord. 2006 Oct;36(7):839-47
references: 16897398
references: J Child Psychol Psychiatry. 1999 Jul;40(5):719-32
references: 10433406
references: J Child Psychol Psychiatry. 2007 Feb;48(2):128-38
references: 17300551
references: J Autism Dev Disord. 1998 Apr;28(2):143-51
references: 9586776
references: J Autism Dev Disord. 2007 Apr;37(4):613-27
references: 17180459
references: Am J Ment Retard. 2006 May;111(3):199-215
references: 16597187
references: J Am Acad Child Adolesc Psychiatry. 1998 Mar;37(3):271-7
references: 9519631
references: J Autism Dev Disord. 1989 Sep;19(3):363-87
references: 2793783
references: J Autism Dev Disord. 2004 Apr;34(2):129-37
references: 15162932
references: J Autism Dev Disord. 1995 Apr;25(2):81-104
references: 7559289
references: J Paediatr Child Health. 2001 Jun;37(3):221-6
references: 11468034
references: J Am Acad Child Adolesc Psychiatry. 2006 Sep;45(9):1094-103
references: 16926617