title: Anti-tubercular agents. Part IV: Synthesis and antimycobacterial evaluation of nitroheterocyclic-based 1,2,4-benzothiadiazines.
abstract: In continuation of our earlier work on benzothiadiazines, we have prepared a series of nitrofuran, nitrothiophene and arylfuran coupled benzothiadiazines and evaluated them for antimycobacterial and antibacterial activities. One of the compounds 2f has shown good in vitro antimycobacterial activity. All the synthesized compounds have shown moderate to good antibacterial activity.
authors: Division of Organic Chemistry, Indian Institute of Chemical Technology, Hyderabad 500 007, India. ahmedkamal@iict.res.in
authors: Ahmed
authors: A
authors: Kamal
authors: S Kaleem
authors: SK
authors: Ahmed
authors: K Srinivasa
authors: KS
authors: Reddy
authors: M Naseer A
authors: MN
authors: Khan
authors: Rajesh V C R N C
authors: RV
authors: Shetty
authors: B
authors: B
authors: Siddhardha
authors: U S N
authors: US
authors: Murthy
authors: Inshad Ali
authors: IA
authors: Khan
authors: Manoj
authors: M
authors: Kumar
authors: Sandeep
authors: S
authors: Sharma
authors: Anshu Beulah
authors: AB
authors: Ram
mesh_terms: D000900:Anti-Bacterial Agents / Q000138:chemical synthesis / Q000494:pharmacology; D000995:Antitubercular Agents / Q000138:chemical synthesis* / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects; D001581:Benzothiadiazines / Q000138:chemical synthesis* / Q000494:pharmacology*; D007202:Indicators and Reagents; D008826:Microbial Sensitivity Tests; D009169:Mycobacterium tuberculosis / Q000187:drug effects; D013329:Structure-Activity Relationship
chemical_list: D000900:Anti-Bacterial Agents; D000995:Antitubercular Agents; D001581:Benzothiadiazines; D007202:Indicators and Reagents