title: Con-Struct Map: a comparative contact map analysis tool.
abstract: Con-Struct Map is a graphical tool for the comparative study of protein structures. The tool detects potential conserved residue contacts shared by multiple protein structures by superimposing their contact maps according to a multiple structure alignment. In general, Con-Struct Map allows the study of structural changes resulting from, e.g. sequence substitutions, or alternatively, the study of conserved components of a structure framework across structurally aligned proteins. Specific applications include the study of sequence-structure relationship in distantly related proteins and the comparisons of wild type and mutant proteins.
  
  
  BACKGROUND
  http://pdbrs3.sdsc.edu/ConStructMap/viewer_argument_generator/singleArguments.
  
  
  BACKGROUND
  Supplementary data are available at Bioinformatics online.
authors: Department of Chemistry and Biochemistry, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA.
authors: Jo-Lan
authors: JL
authors: Chung
authors: John E
authors: JE
authors: Beaver
authors: Eric D
authors: ED
authors: Scheeff
authors: Philip E
authors: PE
authors: Bourne
mesh_terms: D000465:Algorithms; D000595:Amino Acid Sequence; D001665:Binding Sites; D003196:Computer Graphics; D003198:Computer Simulation; D008956:Models, Chemical; D008958:Models, Molecular; D008969:Molecular Sequence Data; D011485:Protein Binding; D025941:Protein Interaction Mapping / Q000379:methods*; D011506:Proteins / Q000737:chemistry* / Q000648:ultrastructure*; D016415:Sequence Alignment / Q000379:methods*; D020539:Sequence Analysis, Protein / Q000379:methods; D012984:Software; D014584:User-Computer Interface
chemical_list: D011506:Proteins