title: Treatment with amniopatch of premature rupture of membranes after first-trimester chorionic villus sampling.
abstract: OBJECTIVE
  To assess the amniopatch procedure when premature rupture of membranes occurs after first-trimester chorionic villus sampling (CVS).
  
  
  METHODS
  From May 2001 to June 2004, the amniopatch procedure was offered in cases of premature rupture of membranes after CVS when severe oligohydramnios was present (largest vertical pocket < 2 cm) and persistent (more than 1 week).
  
  
  RESULTS
  The amniopatch was placed in five pregnancies at 12-18 weeks of gestation, resulting in amniotic fluid restoration in all but one pregnancy. In three pregnancies, fetal demise was observed at 1, 2 and 36 days after the procedure. The last procedure resulted in a healthy newborn.
  
  
  CONCLUSIONS
  Although the amniopatch restored normal amniotic fluid levels in all cases, 4 of the 5 cases resulted in fetal demise.
authors: Institute of Gynecology, Obstetrics and Neonatology, Hospital Clinic, University of Barcelona Medical School, Barcelona, Catalonia, Spain.
authors: Tere
authors: T
authors: Cobo
authors: Antoni
authors: A
authors: Borrell
authors: Albert
authors: A
authors: Fortuny
authors: Sandra
authors: S
authors: Hernández
authors: Marimer
authors: M
authors: Pérez
authors: Montserrat
authors: M
authors: Palacio
authors: Artur
authors: A
authors: Pereira
authors: Oriol
authors: O
authors: Coll
mesh_terms: D015193:Chorionic Villi Sampling / Q000009:adverse effects*; D005260:Female; D005313:Fetal Death; D005322:Premature Rupture of Fetal Membranes / Q000209:etiology* / Q000601:surgery*; D005332:Fetoscopy; D006801:Humans; D016104:Oligohydramnios / Q000601:surgery; D011247:Pregnancy; D011256:Pregnancy Outcome; D011261:Pregnancy Trimester, First