Stimulus motion propels traveling waves in binocular rivalry.
State transitions in the nervous system often take shape as traveling waves, whereby one neural state is replaced by another across space in a wave-like manner. In visual perception, transitions between the two mutually exclusive percepts that alternate when the two eyes view conflicting stimuli (binocular rivalry) may also take shape as traveling waves. The properties of these waves point to a neural substrate of binocular rivalry alternations that have the hallmark signs of lower cortical areas. In a series of experiments, we show a potent interaction between traveling waves in binocular rivalry and stimulus motion. The course of the traveling wave is biased in the motion direction of the suppressed stimulus that gains dominance by means of the wave-like transition. Thus, stimulus motion may propel the traveling wave across the stimulus to the extent that the stimulus motion dictates the traveling wave's direction completely. Using a computational model, we show that a speed-dependent asymmetry in lateral inhibitory connections between retinotopically organized and motion-sensitive neurons can explain our results. We argue that such a change in suppressive connections may play a vital role in the resolution of dynamic occlusion situations.
Knapen
Tomas
T
Helmholtz Institute, Utrecht University, Utrecht, The Netherlands. t.h.j.knapen@phys.uu.nl
van Ee
Raymond
R
Blake
Randolph
R
D003198:Computer Simulation; D023882:Dominance, Ocular / Q000502:physiology*; D006801:Humans; D008959:Models, Neurological; D009039:Motion Perception / Q000502:physiology*; D009474:Neurons / Q000502:physiology; D010775:Photic Stimulation / Q000379:methods*; D015348:Vision, Binocular / Q000502:physiology*; D014795:Visual Pathways / Q000502:physiology
Nature. 2001 Apr 5;410(6829):690-4
11287955
Neuron. 2006 Dec 7;52(5):911-20
17145510
Vision Res. 2002 Feb;42(3):301-9
11809483
Nat Rev Neurosci. 2002 Jan;3(1):13-21
11823801
Nat Rev Neurosci. 2002 Apr;3(4):261-70
11967556
Phys Rev E Stat Nonlin Soft Matter Phys. 2002 May;65(5 Pt 1):051904
12059590
J Neurophysiol. 2003 Feb;89(2):1094-111
12574483
Vision Res. 2003 Sep;43(19):2003-8
12842153
J Neurosci. 2004 Oct 13;24(41):9185-94
15483137
J Physiol. 1977 Dec;273(3):791-803
604459
Percept Psychophys. 1984 Feb;35(2):111-22
6718208
Biol Cybern. 1985;52(6):391-7
4052502
Nature. 1988 May 19;333(6170):265-8
3368003
Nature. 1994 Jun 9;369(6480):479-82
8202137
Nature. 1995 Feb 16;373(6515):609-11
7854417
Science. 1998 Feb 27;279(5355):1351-5
9478895
Neuron. 1998 Mar;20(3):509-26
9539125
Physiol Rev. 1998 Apr;78(2):467-85
9562036
Nat Neurosci. 1999 May;2(5):405-6
10321242
Nat Neurosci. 2005 Jan;8(1):22-3
15580269
PLoS Biol. 2005 Aug;3(8):e265
16018720
Vision Res. 2006 Mar;46(5):605-13
16054190
Trends Neurosci. 2006 Jun;29(6):307-16
16713635
Nature. 2001 Aug 30;412(6850):907-10
11528478