A middle-aged man with newly diagnosed HIV infection and rash.
TEN is a rare cutaneous drug reaction associated with high morbidity and mortality. The underlying pathogenic mechanisms are poorly understood. Development of an effective treatment algorithm has been hampered by the low incidence of this disorder, incomplete knowledge of the mechanisms of epidermal death, and lack of large controlled trials to evaluate therapeutic interventions.
Njoku
Patrick
P
Department of Medicine, Louisiana State University Health Science Center (LSUHSC) School of Medicine, New Orleans, USA.
Tate
Temeka
T
Zadeh
Sousan
S
Hauck
Erin
E
Chaudhry
Anila
A
Lo-Blais
Betty
B
Nesbitt
Lee
L
Sanders
Charles V
CV
Lopez
Fred A
FA
D000890:Anti-Infective Agents / Q000009:adverse effects*; D003937:Diagnosis, Differential; D005076:Exanthema / Q000209:etiology*; D015658:HIV Infections; D006801:Humans; D008297:Male; D008875:Middle Aged; D045363:Pneumocystis carinii / Q000302:isolation & purification; D011020:Pneumonia, Pneumocystis / Q000188:drug therapy*; D013262:Stevens-Johnson Syndrome / Q000175:diagnosis / Q000209:etiology*; D015662:Trimethoprim, Sulfamethoxazole Drug Combination / Q000009:adverse effects*
D000890:Anti-Infective Agents; D015662:Trimethoprim, Sulfamethoxazole Drug Combination