title: Evaluation and indications of ultrasound-guided vacuum-assisted core needle breast biopsy.
abstract: BACKGROUND
  The Mammotome is a diagnostic tool used under stereotactic or with ultrasound guidance. A clear indication for Mammotome use under stereotactic guidance is when a non-palpable microcalcification is a target. However, the indications for the use of the Mammotome under ultrasound guidance vary among institutions, and it is difficult to find a place for the Mammotome among conventional biopsy techniques. The Mammotome biopsy has been available in our hospital since July 1999. We assessed the effectiveness and indications of ultrasound-guided Mammotome biopsy.
  
  
  METHODS
  We performed Mammotome biopsies in 433 cases requiring histological diagnosis from July 1999 to September 2006, using an 11-gauge articulated arm-type Mammotome under ultrasound guidance. There were 377 mass lesions including 83 non-palpable cases and 56 hypoechoic lesions.
  
  
  RESULTS
  The indications for Mammotome biopsy were 162 cases with inconsistent fine needle aspiration (FNA) and imaging findings, 114 cases indeterminate by FNA, 68 cases of an identified pathological type before neoadjuvant chemotherapy and confirmation of hormone receptor status, 36 inadequate cases by FNA, 20 cases of confirmation of fibroadenoma and other benign tumors, 8 removal cases of fibroadenoma, 8 microcalcification cases, and 17 others. The target lesion was obtained in 99.5% of the cases.
  
  
  CONCLUSIONS
  Ultrasound-guided Mammotome biopsy is an accurate and useful diagnostic method that enables sufficient amounts of tissue to be obtained with minimal invasion and few complications. The Mammotome is the first choice for obtaining a definitive pathological diagnosis in breast lesions.
authors: Department of Surgery, Kawaguchi Municipal Medical Center, Kawaguchi-city, Saitama, Japan. satoko_n@f2.dion.ne.jp
authors: Satoko
authors: S
authors: Nakano
authors: Haruko
authors: H
authors: Sakamoto
authors: Masahiko
authors: M
authors: Ohtsuka
authors: Akemi
authors: A
authors: Mibu
authors: Hitomi
authors: H
authors: Sakata
authors: Masahiro
authors: M
authors: Yamamoto
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001707:Biopsy, Needle / Q000379:methods* / Q000706:statistics & numerical data*; D001943:Breast Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000000981:diagnostic imaging* / Q000473:pathology; D005260:Female; D006801:Humans; D007564:Japan; D008875:Middle Aged; D011237:Predictive Value of Tests; D018084:Ultrasonography, Interventional / Q000379:methods / Q000706:statistics & numerical data; D016217:Ultrasonography, Mammary / Q000379:methods / Q000706:statistics & numerical data; D014618:Vacuum