title: NMR study on the adhesion efficacy of experimental phosphonic acid monomers.
abstract: Three experimental self-etching primers - consisting of N-methacryloyl-omega-aminoalkyl phosphonic acid (NMomegaP) with different methylene chain lengths and N-methacryloyl glycine (NMGly) - were formulated. The influence of methylene chain length in NMomegaP derivatives on the chemical nature of calcium salts was examined following their application to tooth components. Bond strengths of experimental self-etching primers created with these monomers to enamel and dentin were also investigated. Nuclear magnetic resonance spectroscopy showed that NMomegaPs decalcified tooth components with formation of calcium salts, which changed from calcium hydrogen phosphonate to calcium phosphonate with increase in methylene chain length within the NMomegaP structure. Disparity in calcium salt formation was related to increases in bond strength to enamel from 18 to 24 MPa. However, bond strength to dentin remained unchanged (22 MPa). The relative dependency of bond strength on monomer methylene chain length was probably attributable to the sites where these NMomegaP calcium salts had deposited on the bonding substrates.
authors: Department of Dental Biomaterials, Nihon University School of Dentistry at Matsudo, 870-1 Sakaecho, Nishi 2, Matsudo, Chiba 271-8587, Japan. nishiyama.norihiro@nihon-u.ac.jp
authors: Norihiro
authors: N
authors: Nishiyama
authors: Masahiro
authors: M
authors: Aida
authors: Kou
authors: K
authors: Fujita
authors: Kazuomi
authors: K
authors: Suzuki
authors: F R
authors: FR
authors: Tay
authors: David H
authors: DH
authors: Pashley
authors: Kimiya
authors: K
authors: Nemoto
mesh_terms: D000134:Acid Etching, Dental / Q000379:methods*; D001840:Dental Bonding / Q000379:methods; D003764:Dental Materials / Q000737:chemistry / Q000494:pharmacology*; D017886:Durapatite / Q000737:chemistry*; D005998:Glycine / Q000031:analogs & derivatives* / Q000737:chemistry / Q000494:pharmacology; D008689:Methacrylates / Q000737:chemistry / Q000494:pharmacology*; D063065:Organophosphonates / Q000737:chemistry / Q000494:pharmacology*; D000267:Tissue Adhesions
chemical_list: D003764:Dental Materials; D008689:Methacrylates; D063065:Organophosphonates; C093041:N-methacryloyl glycine; D017886:Durapatite; D005998:Glycine