title: Listeria as a vaccine vector.
abstract: The immunostimulatory characteristics and intracellular niche of Listeria monocytogenes make it uniquely suitable for use as a live bacterial vaccine vector. Preclinical results supporting this idea, and current strategies to induce beneficial cell-mediated immunity to both infectious diseases and cancer with this vector, are discussed in this review.
authors: Department of Medicine, Division of Dermatology, Los Angeles Biomedical Research Institute at Harbor/UCLA Medical Center, 1124 W. Carson St., Torrance, CA 90502, USA. kbruhn@ucla.edu
authors: Kevin W
authors: KW
authors: Bruhn
authors: Noah
authors: N
authors: Craft
authors: Jeff F
authors: JF
authors: Miller
mesh_terms: D000818:Animals; D001428:Bacterial Vaccines / Q000235:genetics* / Q000276:immunology; D019496:Cancer Vaccines / Q000235:genetics* / Q000276:immunology; D005822:Genetic Vectors / Q000235:genetics / Q000276:immunology; D006801:Humans; D008089:Listeria monocytogenes / Q000235:genetics / Q000276:immunology / Q000502:physiology*; D014612:Vaccines / Q000235:genetics* / Q000276:immunology; D014614:Vaccines, Synthetic / Q000235:genetics / Q000276:immunology
chemical_list: D001428:Bacterial Vaccines; D019496:Cancer Vaccines; D014612:Vaccines; D014614:Vaccines, Synthetic