Smart microrobots for mechanical cell characterization and cell convoying.
This paper deals with the effective design of smart microrobots for both mechanical cell characterization and cell convoying for in vitro fertilization. The first microrobotic device was developed to evaluate oocyte mechanical behavior in order to sort oocytes. A multi-axial micro-force sensor based on a frictionless magnetic bearing was developed. The second microrobotic device presented is a cell convoying device consisting of a wireless micropusher based on magnetic actuation. As wireless capabilities are supported by this microrobotic system, no power supply connections to the micropusher are needed. Preliminary experiments have been performed regarding both cell transporting and biomechanical characterization capabilities under in vitro conditions on human oocytes so as to demonstrate the viability and effectiveness of the proposed setups.
Boukallel
M
M
Robotics Laboratory of Paris (LRP-FRE 2507), 18, route du Panorama, 92265 Fontenay aux Roses, France. boukallel@robot.jussieu.fr
Gauthier
M
M
Dauge
M
M
Piat
E
E
Abadie
J
J
D001696:Biomechanical Phenomena / Q000295:instrumentation / Q000379:methods; D018929:Cell Culture Techniques / Q000295:instrumentation* / Q000379:methods; D002469:Cell Separation / Q000295:instrumentation* / Q000379:methods; D002478:Cells, Cultured; D004867:Equipment Design; D019544:Equipment Failure Analysis; D006801:Humans; D008846:Micromanipulation / Q000295:instrumentation* / Q000379:methods; D008904:Miniaturization; D009865:Oocytes / Q000145:classification / Q000166:cytology / Q000502:physiology*; D010812:Physical Stimulation / Q000295:instrumentation* / Q000379:methods; D012371:Robotics / Q000295:instrumentation* / Q000379:methods