title: Soft shell resins for solid-phase peptide synthesis.
abstract: Soft shell (SS) resins with a lightly or noncross-linked shell layer were prepared by reducing the amount of cross-linking agent, divinylbenzene (DVB), during seed suspension polymerization from polystyrene (PS) resin. These SS resins have a lower swelling volume than that produced by normal cross-linking. Despite its lower swelling, however, SS (10-00) resin, which consists of the 1% DVB-cross-linked core and the noncross-linked surface layer, showed higher efficiency in peptide synthesis compared with 1% DVB-PS resin and other SS resins.
authors: School of Chemical and Biological Engineering, Seoul National University, Seoul 151-744, Republic of Korea.
authors: Tae-Kyung
authors: TK
authors: Lee
authors: Jeong-Hyun
authors: JH
authors: Choi
authors: Sun-Jong
authors: SJ
authors: Ryoo
authors: Yoon-Sik
authors: YS
authors: Lee
mesh_terms: D002851:Chromatography, High Pressure Liquid; D018613:Microscopy, Confocal; D010446:Peptide Fragments / Q000138:chemical synthesis; D010455:Peptides / Q000138:chemical synthesis*; D011137:Polystyrenes / Q000737:chemistry; D012117:Resins, Synthetic / Q000737:chemistry; D014753:Vinyl Compounds / Q000737:chemistry
chemical_list: D010446:Peptide Fragments; D010455:Peptides; D011137:Polystyrenes; D012117:Resins, Synthetic; D014753:Vinyl Compounds; C004985:divinyl benzene