title: The vergence eye movements induced by radial optic flow: some fundamental properties of the underlying local-motion detectors.
abstract: Radial optic flow applied to large random dot patterns is known to elicit horizontal vergence eye movements at short latency, expansion causing convergence and contraction causing divergence: the Radial Flow Vergence Response (RFVR). We elicited RFVRs in human subjects by applying radial motion to concentric circular patterns whose radial luminance modulation was that of a square wave lacking the fundamental: the missing fundamental (mf) stimulus. The radial motion consisted of successive 1/4-wavelength steps, so that the overall pattern and the 4n+1 harmonics (where n=integer) underwent radial expansion (or contraction), whereas the 4n-1 harmonics--including the strongest Fourier component (the 3rd harmonic)--underwent the opposite radial motion. Radial motion commenced only after the subject had fixated the center of the pattern. The initial RFVRs were always in the direction of the 3rd harmonic, e.g., expansion of the mf pattern causing divergence. Thus, the earliest RFVRs were strongly dependent on the motion of the major Fourier component, consistent with early spatio-temporal filtering prior to motion detection, as in the well-known energy model of motion analysis. If the radial mf stimulus was reduced to just two competing harmonics--the 3rd and 5th--the initial RFVRs showed a nonlinear dependence on their relative contrasts: when the two harmonics differed in contrast by more than about an octave then the one with the higher contrast completely dominated the RFVRs and the one with lower contrast lost its influence: winner-take-all. We suggest that these nonlinear interactions result from mutual inhibition between the mechanisms sensing the motion of the different competing harmonics. If single radial-flow steps were used, a brief inter-stimulus interval resulted in reversed RFVRs, consistent with the idea that the motion detectors mediating these responses receive a visual input whose temporal impulse response function is strongly biphasic. Lastly, all of these characteristics of the RFVR, which we attribute to the early cortical processing of visual motion, are known to be shared by the Ocular Following Response (OFR)--a conjugate tracking (version) response elicited at short-latency by linear motion-and even the quantitative details are generally very similar. Thus, although the RFVR and OFR respond to very different patterns of global motion-radial vs. linear-they have very similar local spatiotemporal properties as though mediated by the same low-level, local-motion detectors, which we suggest are in the striate cortex.
authors: Laboratory of Sensorimotor Research, National Eye Institute, National Institutes of Health, Building 49, Room 2A50, 49 Convent Drive, Bethesda, MD 20892-4435, USA.
authors: Y
authors: Y
authors: Kodaka
authors: B M
authors: BM
authors: Sheliga
authors: E J
authors: EJ
authors: FitzGibbon
authors: F A
authors: FA
authors: Miles
mesh_terms: D015350:Contrast Sensitivity / Q000502:physiology; D003290:Convergence, Ocular / Q000502:physiology*; D006801:Humans; D009039:Motion Perception / Q000502:physiology*; D010364:Pattern Recognition, Visual / Q000502:physiology*; D010775:Photic Stimulation / Q000379:methods; D011597:Psychomotor Performance; D011601:Psychophysics; D011930:Reaction Time / Q000502:physiology; D014793:Visual Cortex / Q000502:physiology
references: Curr Biol. 1998 Jul 30-Aug 13;8(16):R554-6
references: 9707391
references: Biol Cybern. 1998 Jun;78(6):465-77
references: 9711820
references: Eur J Neurosci. 1998 Mar;10(3):811-22
references: 9753150
references: Neurosci Res. 1998 Oct;32(2):185-8
references: 9858026
references: J Neurophysiol. 1999 Feb;81(2):945-9
references: 10036301
references: J Neurosci. 1999 Aug 15;19(16):7162-74
references: 10436069
references: Vision Res. 1999 Aug;39(17):2853-65
references: 10492815
references: Percept Psychophys. 1999 Aug;61(6):1066-74
references: 10497428
references: Int Rev Neurobiol. 2000;44:199-218
references: 10605647
references: Vision Res. 2000;40(16):2135-47
references: 10878275
references: J Neurophysiol. 2000 Dec;84(6):2725-38
references: 11110803
references: Vis Neurosci. 2000 Sep-Oct;17(5):753-67
references: 11153655
references: J Neurophysiol. 2001 Mar;85(3):1129-52
references: 11247983
references: J Opt Soc Am A Opt Image Sci Vis. 2001 Apr;18(4):755-64
references: 11318325
references: Vision Res. 2001;41(25-26):3371-87
references: 11718780
references: Ann N Y Acad Sci. 2002 Apr;956:456-9
references: 11960839
references: J Neurosci. 2002 Jun 15;22(12):5149-63
references: 12077210
references: J Neurophysiol. 2002 Aug;88(2):888-913
references: 12163540
references: Vision Res. 2002 Aug;42(17):2081-7
references: 12169427
references: Vision Res. 2002 Nov;42(26):2853-67
references: 12450510
references: J Neurophysiol. 2002 Dec;88(6):3398-408
references: 12466456
references: Vision Res. 2003 Feb;43(4):431-43
references: 12536000
references: Vision Res. 2003 Jun;43(12):1387-96
references: 12742108
references: J Neurophysiol. 2003 Sep;90(3):1887-903
references: 12966180
references: J Neurophysiol. 2003 Nov;90(5):2795-817
references: 12867533
references: J Physiol. 1966 Aug;185(3):536-55
references: 5918058
references: Vision Res. 1974 Jul;14(7):519-27
references: 4423193
references: Nature. 1975 Apr 24;254(5502):692-4
references: 1124126
references: Vision Res. 1975 Mar;15(3):447-50
references: 1136166
references: J Neurophysiol. 1982 Jul;48(1):217-37
references: 7119846
references: IEEE Trans Biomed Eng. 1982 Oct;29(10):686-93
references: 6897393
references: J Physiol. 1982 Sep;330:125-43
references: 7175738
references: J Neurosci. 1983 Dec;3(12):2563-86
references: 6655500
references: J Opt Soc Am A. 1984 May;1(5):451-73
references: 6726493
references: J Opt Soc Am A. 1984 Aug;1(8):876-84
references: 6470838
references: J Opt Soc Am A. 1985 Feb;2(2):284-99
references: 3973762
references: J Opt Soc Am A. 1985 Feb;2(2):300-21
references: 3973763
references: J Opt Soc Am A. 1985 Feb;2(2):322-41
references: 3973764
references: J Neurosci. 1986 Jan;6(1):134-44
references: 3944614
references: J Neurosci. 1986 Jan;6(1):145-57
references: 3944616
references: J Comp Neurol. 1986 Jun 8;248(2):190-222
references: 3722458
references: J Neurophysiol. 1986 Jun;55(6):1308-27
references: 3016210
references: Q J Exp Psychol A. 1983 Aug;35(Pt 3):513-8
references: 6571322
references: J Neurophysiol. 1986 Nov;56(5):1321-54
references: 3794772
references: Vision Res. 1992 Nov;32(11):2093-106
references: 1304087
references: Vision Res. 1993 Sep;33(14):2013-9
references: 8249316
references: Science. 1994 May 27;264(5163):1333-6
references: 8191289
references: J Neurophysiol. 1994 May;71(5):1597-626
references: 8064337
references: J Opt Soc Am A Opt Image Sci Vis. 1994 Jul;11(7):1940-8
references: 8071735
references: Vision Res. 1994 Dec;34(23):3223-40
references: 7975353
references: J Neurosci. 1994 Dec;14(12):7357-66
references: 7996181
references: J Neurosci. 1994 Dec;14(12):7367-80
references: 7996182
references: Nature. 1995 Feb 16;373(6515):609-11
references: 7854417
references: J Neurosci. 1995 Jul;15(7 Pt 2):5192-208
references: 7623145
references: Vision Res. 1995 Oct;35(19):2697-722
references: 7483311
references: J Neurosci. 1995 Nov;15(11):7472-84
references: 7472499
references: J Neurophysiol. 1996 Apr;75(4):1392-410
references: 8727386
references: Vis Neurosci. 1995 Nov-Dec;12(6):1191-210
references: 8962836
references: J Neurophysiol. 1996 Aug;76(2):1356-60
references: 8871243
references: J Neurosci. 1996 Dec 1;16(23):7733-41
references: 8922429
references: J Neurophysiol. 1997 Feb;77(2):782-96
references: 9065850
references: Vis Neurosci. 1997 Mar-Apr;14(2):323-38
references: 9147484
references: J Neurosci. 1997 Apr 15;17(8):2839-51
references: 9092605
references: Vision Res. 1997 Mar;37(6):745-55
references: 9156219
references: Spat Vis. 1997;10(4):433-6
references: 9176952
references: Spat Vis. 1997;10(4):437-42
references: 9176953
references: Exp Brain Res. 1997 May;114(3):472-82
references: 9187283
references: Nature. 1997 Sep 18;389(6648):283-6
references: 9305842
references: J Neurosci. 1997 Nov 1;17(21):8621-44
references: 9334433
references: Nature. 1997 Dec 4;390(6659):512-5
references: 9394000
references: Vision Res. 1998 Mar;38(6):795-812
references: 9624431
references: Vision Res. 1998 Mar;38(6):895-909
references: 9624439
references: J Neurophysiol. 1999 Oct;82(4):1710-27
references: 10515961
references: IEEE Trans Biomed Eng. 1963 Oct;10:137-45
references: 14121113
references: J Neurophysiol. 2005 Mar;93(3):1235-45
references: 15483064
references: Ann N Y Acad Sci. 2005 Apr;1039:252-9
references: 15826979
references: Ann N Y Acad Sci. 2005 Apr;1039:260-71
references: 15826980
references: Neuron. 2005 Jun 16;46(6):945-56
references: 15953422
references: Annu Rev Neurosci. 2005;28:157-89
references: 16022593
references: Vision Res. 2005 Nov;45(25-26):3307-21
references: 15894346
references: Vision Res. 2006 Mar;46(6-7):979-92
references: 16242168
references: Vision Res. 2006 Mar;46(6-7):869-78
references: 16356529
references: Vision Res. 2006 Jun;46(13):2041-60
references: 16487988
references: J Neurosci. 2006 Mar 15;26(11):2941-50
references: 16540571
references: J Neurophysiol. 2006 Jun;95(6):3712-26
references: 16554515
references: Vision Res. 2006 Oct;46(21):3723-40
references: 16765403
references: Nat Neurosci. 2006 Nov;9(11):1421-31
references: 17041595
references: J Neurosci. 2007 Jan 17;27(3):529-41
references: 17234585
references: Vision Res. 2007 Feb;47(4):479-500
references: 17118422
references: J Opt Soc Am A Opt Image Sci Vis. 2001 Sep;18(9):2331-70
references: 11551067
references: J Neurophysiol. 1986 Nov;56(5):1381-96
references: 3794774
references: J Neurosci. 1987 Nov;7(11):3416-68
references: 3316524
references: Vision Res. 1987;27(12):2035-48
references: 3447355
references: Science. 1988 May 6;240(4853):740-9
references: 3283936
references: J Opt Soc Am A. 1988 Nov;5(11):1986-2007
references: 3210090
references: J Neurosci. 1989 Jun;9(6):2033-50
references: 2723765
references: J Neurophysiol. 1989 Sep;62(3):626-41
references: 2769351
references: Vision Res. 1988;28(12):1311-3
references: 3256148
references: Vision Res. 1990;30(1):1-10
references: 2321355
references: Vision Res. 1989;29(11):1511-23
references: 2635477
references: Vision Res. 1990;30(4):615-9
references: 2339514
references: Vision Res. 1990;30(5):757-68
references: 2378068
references: Science. 1990 Aug 31;249(4972):1037-41
references: 2396096
references: J Neurosci. 1990 Oct;10(10):3323-34
references: 2213142
references: Vis Neurosci. 1990 Oct;5(4):321-46
references: 2265148
references: Vis Neurosci. 1990 Oct;5(4):347-52
references: 2265149
references: Spat Vis. 1989;4(2-3):103-29
references: 2487159
references: J Neurophysiol. 1991 Jun;65(6):1329-45
references: 1875243
references: J Neurophysiol. 1991 Jun;65(6):1346-59
references: 1875244
references: J Neurosci. 1991 Sep;11(9):2768-85
references: 1880548
references: J Neurophysiol. 1991 Sep;66(3):865-78
references: 1753291
references: J Neurophysiol. 1992 Jun;67(6):1437-46
references: 1629756
references: Science. 1992 Sep 11;257(5076):1563-5
references: 1523411