title: Ambulation in adults with myelomeningocele. Is it possible to predict the level of ambulation in early life?
abstract: OBJECTIVE
  The objective of this study was to evaluate the prediction of ambulation in adults with myelomeningocele from muscle strength testing and ambulation in early life.
  
  
  METHODS
  Fifty-two myelomeningocele (MMC) individuals at the age 18-37 years at follow-up were studied. Information on muscle strength and ambulatory function in early life was retrieved from medical records. The motor levels determined by the muscle strength were used to predict ambulatory function later in life. At follow-up, a clinical examination was performed.
  
  
  RESULTS
  Of 20 MMC individuals assessed with muscle strength within the first year of life, 7 achieved the predicted ambulatory function, 6 had a better, and 7 a poorer function. Of 32 individuals with known muscle strength at the age of 5-8 years, 10 had function as predicted, 5 a better ambulatory function, and 17 had a poorer ambulation in adult life than predicted. Good strength in quadriceps muscles gave significant better prospect for adult walking. Of the 52 participants, 41 retained their ambulation status from 5-8 years of age.
  
  
  CONCLUSIONS
  For MMC individuals with motor levels L3-L5, adult ambulatory function cannot be determined from muscle strength in early life, while it to some extend can be predicted for motor levels at or above L2 and at or below S1. The majority of the participants who at the age 5-8 years were community walkers without walking aid kept that function.
authors: Physiotherapy Department, Clinic for Orthopedics and Rehabilitation Rigshospitalet T4114, Copenhagen University Hospital, Blegdamsvej 9, DK-2100, Copenhagen, Denmark.
authors: Aase
authors: A
authors: Seitzberg
authors: Marianne
authors: M
authors: Lind
authors: Fin
authors: F
authors: Biering-Sørensen
mesh_terms: D000293:Adolescent; D000328:Adult; D002557:Cerebrospinal Fluid Shunts; D002675:Child, Preschool; D003072:Cognition Disorders / Q000503:physiopathology; D003286:Contracture / Q000453:epidemiology / Q000209:etiology; D005260:Female; D005544:Forecasting; D020233:Gait Disorders, Neurologic / Q000209:etiology / Q000503:physiopathology*; D006801:Humans; D006849:Hydrocephalus / Q000209:etiology / Q000601:surgery; D007719:Knee Joint / Q000503:physiopathology; D008297:Male; D008591:Meningomyelocele / Q000150:complications / Q000503:physiopathology*; D053580:Muscle Strength / Q000502:physiology*; D052097:Quadriceps Muscle / Q000503:physiopathology; D016138:Walking
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