title: New pregnane glycosides from the roots of Cynanchum otophyllum.
abstract: Six new pregnane glycosides with an acyl at C-12 and a straight sugar chain at C-3, namely otophyllosides H-M (1-6), were isolated from the roots of Cynanchum otophyllum (Asclepiadaceae) collected from Eryuan County in Yunnan province of China. Their structures were characterized to be qingyangshengenin 3-O-beta-d-glucopyranosyl-(1-->4)-beta-d-glucopyranosyl-(1-->4)-beta-d-cymaropyranosyl-(1-->4)-beta-d-oleandropyranosyl-(1-->4)-beta-d-digitoxopyranoside (1), qingyangshengenin 3-O-beta-d-glucopyranosyl-(1-->4)-beta-d-oleandropyranosyl-(1-->4)-beta-d-cymaropyranosyl-(1-->4)-beta-d-digitoxopyranoside (2), qingyangshengenin 3-O-beta-d-glucopyranosyl-(1-->4)-beta-d-cymaropyranosyl-(1-->4)-beta-d-oleandropyranosyl-(1-->4)-beta-d-cymaropyranosyl-(1-->4)-beta-d-digitoxopyranoside (3), qingyangshengenin 3-O-beta-d-glucopyranosyl-(1-->4)-beta-d-thevetopyranosyl-(1-->4)-beta-d-cymaropyranosyl-(1-->4)-beta-d-digitoxopyranoside (4), caudatin 3-O-beta-d-glucopyranosyl-(1-->4)-beta-d-glucopyranosyl-(1-->4)-beta-d-cymaropyranosyl-(1-->4)-beta-d-oleandropyranosyl-(1-->4)-beta-d-cymaropyranoside (5), caudatin 3-O-beta-d-glucopyranosyl-(1-->4)-beta-d-cymaropyranosyl-(1-->4)-beta-d-oleandropyranosyl-(1-->4)-beta-d-cymaropyranosyl-(1-->4)-beta-d-cymaropyranoside (6), respectively, on the basis of detailed spectroscopic analysis and chemical method.
authors: State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, PR China.
authors: Xiao-Xia
authors: XX
authors: Ma
authors: Fang-Ting
authors: FT
authors: Jiang
authors: Qing-Xiong
authors: QX
authors: Yang
authors: Xiu-Hua
authors: XH
authors: Liu
authors: Ying-Jun
authors: YJ
authors: Zhang
authors: Chong-Ren
authors: CR
authors: Yang
mesh_terms: D002236:Carbohydrate Conformation; D002240:Carbohydrate Sequence; D002247:Carbon Isotopes; D031105:Cynanchum / Q000737:chemistry*; D006027:Glycosides / Q000737:chemistry* / Q000302:isolation & purification*; D009682:Magnetic Resonance Spectroscopy; D008969:Molecular Sequence Data; D018517:Plant Roots / Q000737:chemistry*; D013260:Steroids, Heterocyclic / Q000737:chemistry* / Q000302:isolation & purification*
chemical_list: D002247:Carbon Isotopes; D006027:Glycosides; D013260:Steroids, Heterocyclic