Analyzing the activity of large populations of neurons: how tractable is the problem?
Understanding how the brain performs computations requires understanding neuronal firing patterns at successive levels of processing-a daunting and seemingly intractable task. Two recent studies have made dramatic progress on this problem by showing how its dimensionality can be reduced. Using the retina as a model system, they demonstrated that multineuronal firing patterns can be predicted by pairwise interactions.
Nirenberg
Sheila H
SH
Department of Physiology and Biophysics, Weill Medical College of Cornell University, 1300 York Avenue, New York, NY 10021, USA. shn201@med.cornell.edu
Victor
Jonathan D
JD
D000200:Action Potentials / Q000502:physiology*; D000818:Animals; D001921:Brain / Q000166:cytology* / Q000502:physiology*; D003627:Data Interpretation, Statistical; D006801:Humans; D016571:Neural Networks, Computer; D009474:Neurons / Q000502:physiology*; D012160:Retina / Q000166:cytology / Q000502:physiology; D018401:Sample Size
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