title: Sympathoadrenergic overstimulation in Tako-Tsubo cardiomyopathy triggered by physical and emotional stress.
abstract: Tako-Tsubo cardiomyopathy (TTC) which is usually precipitated by profound emotional stress has been widely reported in the past. Recently, several co-morbidities have been found to be associated with this new cardiac entity. In this case we report from a female patient suffering from both, physical and emotional stress. After a persistent episode of severe abdominal pain due to acute cholecystitis and recurrent events of emotional stress, characteristic features of TTC could be documented. Histopathological analysis documented characteristic structural alterations including contraction band necrosis. Thus, this case confirms the hypothesis of an overstimulated sympthatoadrenergic system in TTC resulting from both, severe physical and emotional stress.
authors: Holger M
authors: HM
authors: Nef
authors: Helge
authors: H
authors: Möllmann
authors: Pirmin
authors: P
authors: Hilpert
authors: Franz
authors: F
authors: Masseli
authors: Sawa
authors: S
authors: Kostin
authors: Christian
authors: C
authors: Troidl
authors: Andreas
authors: A
authors: Rolf
authors: Thorsten
authors: T
authors: Dill
authors: Michael
authors: M
authors: Weber
authors: Christian
authors: C
authors: Hamm
authors: A
authors: A
authors: Elsässer
mesh_terms: D005260:Female; D006801:Humans; D008875:Middle Aged; D013312:Stress, Physiological / Q000502:physiology; D013315:Stress, Psychological / Q000150:complications / Q000175:diagnosis* / Q000523:psychology; D013564:Sympathetic Nervous System / Q000502:physiology; D054549:Takotsubo Cardiomyopathy / Q000175:diagnosis* / Q000209:etiology / Q000523:psychology