Does distress tolerance moderate the impact of major life events on psychosocial variables and behaviors important in the management of HIV?
Living with HIV involves management of multiple stressful disease-related and other life events. Distress tolerance may provide a functional, individual-based context for qualifying the established relationships between major life events and psychosocial variables important in the management of HIV. The present study provided a preliminary test of the hypothesis that distress tolerance moderates the impact of major life events on these predictors of disease progression. HIV-positive patients (n=116) completed psychosocial and medical questionnaires. Results indicated that major life events interacted with distress tolerance such that lower distress tolerance and higher life events were associated with significantly higher levels of depressive symptoms, substance use coping, alcohol and cocaine use, and medication adherence. In addition, distress tolerance was directly related to self-reported HIV-related symptoms. These results suggest that low distress tolerance, particularly in the face of major life events, may present significant challenges to adaptive management of HIV. Distress tolerance assessment may help to specify targets for cognitive-behavioral and stress management treatments for people living with HIV.
O'Cleirigh
Conall
C
University of Miami, Miami, FL, USA. cocleirigh@partners.org
Ironson
Gail
G
Smits
Jasper A J
JA
D000223:Adaptation, Psychological; D000328:Adult; D000368:Aged; D000437:Alcoholism / Q000175:diagnosis / Q000523:psychology; D001143:Arousal; D019970:Cocaine-Related Disorders / Q000175:diagnosis / Q000523:psychology; D003866:Depressive Disorder / Q000175:diagnosis / Q000523:psychology; D018450:Disease Progression; D005260:Female; D006679:HIV Seropositivity / Q000523:psychology*; D006801:Humans; D008016:Life Change Events; D008297:Male; D008875:Middle Aged; D010349:Patient Compliance / Q000523:psychology; D012803:Sick Role; D013223:Statistics as Topic; D019966:Substance-Related Disorders / Q000175:diagnosis / Q000523:psychology
Behav Res Ther. 2006 Sep;44(9):1337-46
16337606
Psychiatr Clin North Am. 1994 Mar;17(1):17-33
8190664
Psychosom Med. 1999 May-Jun;61(3):397-406
10367622
Am J Psychiatry. 1991 Jun;148(6):733-8
1674646
Health Psychol. 2000 Mar;19(2):124-33
10762096
Biol Psychiatry. 2003 Aug 1;54(3):295-306
12893105
Int J Behav Med. 1994;1(1):90-105
16250807
J Behav Med. 2005 Oct;28(5):403-14
16179979
Behav Med. 2002 Summer;28(2):53-60
12613286
Ann Behav Med. 2003 Summer;25(3):203-13
12763715
J Abnorm Psychol. 1999 Aug;108(3):532-7
10466277
AIDS Behav. 2004 Jun;8(2):175-83
15187479
AIDS Educ Prev. 1995;7(5 Suppl):36-47
8664097
Behav Res Ther. 2001 Oct;39(10):1151-62
11579986
Int J STD AIDS. 2004 Dec;15(12):803-10
15601486
AIDS Care. 2000 Jun;12(3):255-66
10928201
J Psychosom Res. 1993 Jan;37(1):39-51
8421259
AIDS Educ Prev. 2003 Feb;15(1 Suppl A):66-79
12630600
Clin Infect Dis. 2001 Oct 15;33(8):1417-23
11550118
AIDS. 2002 Mar 29;16(5):767-74
11964533
AIDS. 2000 Mar 10;14(4):357-66
10770537
Psychosom Med. 2005 Nov-Dec;67(6):1013-21
16314608
Psychol Med. 2002 Aug;32(6):1059-73
12214787
AIDS. 1993 Nov;7(11):1493-9
8280417
AIDS Patient Care STDS. 2006 Jun;20(6):418-28
16789855
Psychosom Med. 2006 Jan-Feb;68(1):143-51
16449425
Pain. 2002 Jul;98(1-2):9-17
12098612
AIDS. 2005 Apr;19 Suppl 1:S49-55
15838194
Health Psychol. 1997 Jul;16(4):369-73
9237089
JAMA. 2001 Mar 21;285(11):1466-74
11255423
AIDS Care. 1998 Jun;10(3):297-312
9828973
AIDS Behav. 2006 Sep;10(5):473-82
16604295
J Consult Clin Psychol. 1978 Oct;46(5):932-46
701572
JAMA. 2000 Jan 19;283(3):381-90
10647802
J Abnorm Psychol. 1997 Aug;106(3):355-64
9241937
AIDS Care. 2004 May;16(4):446-57
15203413
Psychiatry. 1995 Nov;58(4):299-312
8746489
Addict Behav. 2003 Apr;28(3):523-36
12628624
Ann Behav Med. 1996 Mar;18(1):30-9
24203641
J Acquir Immune Defic Syndr. 2006 Jul;42(3):298-306
16639343
J Pers Soc Psychol. 1989 Feb;56(2):267-83
2926629
AIDS Care. 2005 May;17(4):433-42
16036228
J Behav Med. 2003 Apr;26(2):165-81
12776385
Psychosom Med. 2005 May-Jun;67(3):500-7
15911916
J Psychosom Res. 2003 Mar;54(3):225-35
12614832
Psychol Med. 1997 Mar;27(2):395-409
9089832
J Pers Soc Psychol. 1986 Dec;51(6):1173-82
3806354
Am J Psychiatry. 2000 May;157(5):751-8
10784468
Sex Transm Infect. 2003 Apr;79(2):142-6
12690138
JAMA. 1998 Jul 1;280(1):72-7
9660367
J Abnorm Psychol. 2002 Feb;111(1):180-5
11866171