title: Bologna transplant center results in double kidney transplantation: update.
abstract: BACKGROUND
  Double-kidney transplantation is performed using organs from marginal donors with a histological score not suitable for single kidney transplantation. The aim of this study was to verify the results obtained with double-kidney transplantation in terms of graft/patient survivals and complications.
  
  
  METHODS
  Between September 2001 and September 2006. 26 double-kidney transplantations were performed in our center. Indications for surgery were: chronic glomerulonephritis (n = 17), polycystic disease (n = 4), reflux nephropathy (n = 1), hypertensive nephroangiosclerosis (n = 4). The kidneys were all perfused with Celsior solution and mean cold ischemia time was 16.7 +/- 2.5 hours. In all cases, a pretransplant kidney biopsy was performed to evaluate the damage (mean score: 4.3). Immunosuppression was tacrolimus-based for all patients.
  
  
  RESULTS
  Eighteen patients had good renal postoperative function, while the other eight displayed acute tubular necrosis. Two of the patients who had severe acute tubular necrosis never recovered renal function. There was only one episode of acute rejection, while the incidence of urinary complications was 31%. There were two surgical reoperations for intestinal perforation. Graft and recipient survivals were 82.7% and 100%, and 78.9% and 94% at 3 and 36 months, respectively.
  
  
  CONCLUSIONS
  Double-kidney transplantation is a safe strategy to face the organ shortage. The score used in this study is useful to determine whether a kidney should be refused or suitable for single- or dual-kidney transplantation. The results of our experience are encouraging, but the series is too small to allow a conclusion.
authors: Department of Surgery, Intensive Care Unit and Transplantations, S Orsola Hospital, University of Bologna, Bologna, Italy.
authors: R
authors: R
authors: Bertelli
authors: G
authors: G
authors: Varotti
authors: L
authors: L
authors: Puviani
authors: G
authors: G
authors: Cavallari
authors: V
authors: V
authors: Pacilè
authors: D
authors: D
authors: Prezzi
authors: M
authors: M
authors: Tsivian
authors: F
authors: F
authors: Neri
authors: G Liviano
authors: GL
authors: D'Arcangelo
authors: G
authors: G
authors: Mosconi
authors: S
authors: S
authors: Stefoni
authors: G
authors: G
authors: Fuga
authors: A
authors: A
authors: Faenza
authors: B
authors: B
authors: Nardo
mesh_terms: D006085:Graft Survival; D007558:Italy; D007674:Kidney Diseases / Q000145:classification / Q000601:surgery; D016030:Kidney Transplantation / Q000379:methods* / Q000473:pathology / Q000502:physiology; D007683:Kidney Tubular Necrosis, Acute / Q000473:pathology; D011183:Postoperative Complications / Q000473:pathology; D012189:Retrospective Studies; D014019:Tissue Donors / Q000706:statistics & numerical data