Promiscuous zinc-dependent acylase-mediated carbon-carbon bond formation in organic media.
A zinc-dependent acylase, D-aminoacylase from Escherichia. Coli, displays a promiscuous activity to catalyze the carbon-carbon bond formation reaction of 1,3-dicarbonyl compounds to methyl vinyl ketone in organic media.
Xu
Jian-Ming
JM
Department of Chemistry, Zhejiang University, Hangzhou 310027, People's Republic of China.
Zhang
Fu
F
Liu
Bo-Kai
BK
Wu
Qi
Q
Lin
Xian-Fu
XF
D000581:Amidohydrolases / Q000378:metabolism*; D001665:Binding Sites; D002244:Carbon / Q000737:chemistry* / Q000378:metabolism*; D002384:Catalysis; D002413:Cations, Divalent / Q000737:chemistry; D004926:Escherichia coli / Q000201:enzymology; D008745:Methylation; D015394:Molecular Structure; D009930:Organic Chemicals; D012997:Solvents; D015032:Zinc / Q000737:chemistry / Q000378:metabolism*
D002413:Cations, Divalent; D009930:Organic Chemicals; D012997:Solvents; D002244:Carbon; D000581:Amidohydrolases; C019665:amidase; D015032:Zinc