Synovial sarcoma of the sellar region.
Primary sarcomas of the sellar region are uncommon, although a wide variety have been reported. To date, no cases of primary synovial sarcoma have been described as occurring at this site. We report an immunohistochemically and molecular genetically confirmed primary synovial sarcoma involving the sellar/parasellar region and cavernous sinus in an adult male. Subtotal resection and radiosurgery proved to be efficacious. The spectrum of primary sellar region sarcomas is summarized.
Scheithauer
Bernd W
BW
Department of Laboratory Medicine and Pathology, Mayo Clinic, 200 First St., SW, Rochester, MN 55905, USA. scheithauer.bernd@mayo.edu
Silva
Ana Isabel
AI
Kattner
Keith
K
Seibly
Jason
J
Oliveira
Andre M
AM
Kovacs
Kalman
K
D002426:Cavernous Sinus / Q000473:pathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000473:pathology; D019635:Neurosurgical Procedures; D015514:Oncogene Proteins, Fusion; D016634:Radiosurgery; D020133:Reverse Transcriptase Polymerase Chain Reaction; D013584:Sarcoma, Synovial / Q000235:genetics / Q000473:pathology* / Q000628:therapy*; D012658:Sella Turcica / Q000473:pathology*; D019292:Skull Base Neoplasms / Q000235:genetics / Q000473:pathology* / Q000628:therapy*; D014178:Translocation, Genetic
D015514:Oncogene Proteins, Fusion; C116512:SYT-SSX fusion protein
J Clin Oncol. 1996 Mar;14(3):859-68
8622034
AJR Am J Roentgenol. 2002 Sep;179(3):797-801
12185067
Hum Pathol. 1998 Mar;29(3):240-5
9496826
J Clin Endocrinol Metab. 2005 Feb;90(2):800-4
15562021
Surg Neurol. 1984 Sep;22(3):277-84
6463839
Acta Neurochir (Wien). 1996;138(12):1470-1
9030357
Endocr Pract. 2005 May-Jun;11(3):184-9
16239205
Endocr Pract. 2004 Jul-Aug;10(4):335-8
15760777
Br J Neurosurg. 1988;2(1):101-7
3268152
Hum Pathol. 1991 Jan;22(1):84-91
1985083
J Neurosurg. 1980 Sep;53(3):401-5
7420156
J Neurosurg. 2003 Jun;98(6):1182-7
12816261
Endocr Pathol. 2004 Summer;15(2):149-58
15299201
J Pediatr Hematol Oncol. 2005 Apr;27(4):207-11
15838392
AJR Am J Roentgenol. 1993 Oct;161(4):827-30
8396848
J Neurosurg. 2000 Jun;92(6):976-82
10839258
Mod Pathol. 1998 Jun;11(6):579-84
9647597
Am J Surg Pathol. 1997 Dec;21(12):1455-65
9414189
J Clin Oncol. 2000 Nov 15;18(22):3794-803
11078492
J Clin Oncol. 2000 May;18(10):2087-94
10811674
Acta Neurochir (Wien). 1987;88(3-4):142-6
3687501
Neurosurgery. 1997 Sep;41(3):542-50; discussion 551-2
9310970
Hum Pathol. 1990 Jul;21(7):733-49
2163364
J Pediatr Surg. 1999 May;34(5):672-5
10359161
Surg Neurol. 1986 Sep;26(3):271-6
3738722
Skeletal Radiol. 2001 Jan;30(1):25-30
11289631
Acta Neurochir (Wien). 1983;67(3-4):181-94
6846075
Cancer. 1993 Nov 15;72(10):2943-9
7693324
Virchows Arch. 2001 Apr;438(4):321-35
11355165
Am J Clin Pathol. 1996 Aug;106(2):217-24
8712177
Clin Plast Surg. 1995 Jul;22(3):407-16
7554714
Hum Pathol. 1998 Feb;29(2):190-3
9490282
Neurosurgery. 2001 Mar;48(3):677-80
11270561
Cancer. 1975 May;35(5):1478-83
1122498
J Neurosurg. 2005 Dec;103(6):1077-80
16381195
J Clin Oncol. 2003 Apr 15;21(8):1602-11
12697886
J Am Coll Surg. 2001 Mar;192(3):305-13
11245372
Can J Neurol Sci. 2003 Nov;30(4):378-83
14672272
Cancer. 1999 May 1;85(9):2046-56
10223247
Am J Ophthalmol. 2002 Nov;134(5):785-7
12429268
Cancer. 1992 Jul 15;70(2):484-9
1319818
J Clin Endocrinol Metab. 2001 Jan;86(1):386-91
11232029
Skull Base. 2003 May;13(2):79-83
15912163
Acta Neurochir (Wien). 2003 Jul;145(7):593-7; discussion 597
12910404
J Neurosurg. 2002 May;96(5):960-3
12005408
J Bone Joint Surg Am. 1982 Jan;64(1):112-22
6274877
Am J Surg Pathol. 1997 Nov;21(11):1354-60
9351573
Cancer. 1977 Mar;39(3):1201-17
199345
Diagn Mol Pathol. 2003 Dec;12(4):224-30
14639108
Surg Neurol. 2004 Dec;62(6):522-9; discussion 529-30
15576120
J Neurooncol. 1998 Oct;40(1):87-96
9874190