title: Association between renal hypoechoic subcapsular thickening and lymphosarcoma in cats.
abstract: The purpose of this study was to investigate the association between renal hypoechoic subcapsular thickening observed ultrasonographically and the presence of renal lymphosarcoma in cats. The ultrasonography database was retrospectively searched for cats that underwent ultrasound examination and ultrasound guided needle renal aspirate, renal biopsy, or necropsy. One radiologist unaware of the final diagnosis evaluated the images for the presence of hypoechoic subcapsular thickening and other abnormal findings. Fifty-four cats met the inclusion criteria. Hypoechoic subcapsular thickening was found in 21 cats of which 17 had lymphosarcoma; the remaining four cats had a different diagnosis. Eleven out of 33 cats without hypoechoic subcapsular thickening were positive for lymphosarcoma, and the rest had a different diagnosis. There was a significant association between hypoechoic subcapsular thickening and renal lymphosarcoma (P = 0.001). The positive predictive value of hypoechoic subcapsular thickening for lymphosarcoma was 80.9% and the negative predictive value was 66.7%. The sensitivity and specificity of hypoechoic subcapsular thickening for the diagnosis of renal lymphosarcoma were 60.7% and 84.6%, respectively. The results of this study indicate that the presence of hypoechoic subcapsular thickening in feline kidneys is associated with renal lymphosarcoma.
authors: Department of Clinical Studies, Section of Radiology, Ryan Veterinary Hospital, University of Pennsylvania, 3900 Delancey Street, Philadelphia, PA 19104, USA. alejandv@vet.upenn.edu
authors: Alejandro
authors: A
authors: Valdés-Martínez
authors: Rachel
authors: R
authors: Cianciolo
authors: Wilfried
authors: W
authors: Mai
mesh_terms: D000818:Animals; D002371:Cat Diseases / Q000000981:diagnostic imaging* / Q000473:pathology; D002415:Cats; D005260:Female; D007668:Kidney / Q000000981:diagnostic imaging* / Q000473:pathology; D007680:Kidney Neoplasms / Q000000981:diagnostic imaging / Q000662:veterinary*; D008228:Lymphoma, Non-Hodgkin / Q000000981:diagnostic imaging / Q000662:veterinary*; D008297:Male; D008499:Medical Records; D011237:Predictive Value of Tests; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D014463:Ultrasonography / Q000662:veterinary