title: The transcription profile of the bocavirus bovine parvovirus is unlike those of previously characterized parvoviruses.
abstract: The Bocavirus bovine parvovirus generated a single pre-mRNA from a promoter at its left-hand end; however, the pattern of its alternative polyadenylation and splicing was different from that of other parvoviruses. A large left-hand-end open reading frame (ORF) encoded a nonstructural protein of approximately 95 kDa. An abundant, spliced, internally polyadenylated transcript encoded the viral NP1 protein from an ORF in the center of the genome. Transcripts encoding the capsid proteins were polyadenylated in the right-hand terminal palindrome. This is the first published transcription map of a member of the Bocavirus genus of the Parvovirinae.
authors: Department of Microbiology, Molecular Genetics and Immunology, University of Kansas Medical Center, 3901 Rainbow Blvd., Kansas City, KS 66160, USA. jqiu@kumc.edu
authors: Jianming
authors: J
authors: Qiu
authors: Fang
authors: F
authors: Cheng
authors: F Brent
authors: FB
authors: Johnson
authors: David
authors: D
authors: Pintel
mesh_terms: D001483:Base Sequence; D052660:Bocavirus / Q000235:genetics*; D002460:Cell Line; D003001:Cloning, Molecular; D016679:Genome, Viral; D006801:Humans; D008957:Models, Genetic; D008969:Molecular Sequence Data; D016366:Open Reading Frames; D017992:Parvovirus / Q000235:genetics*; D017434:Protein Structure, Tertiary; D012333:RNA, Messenger / Q000378:metabolism; D013045:Species Specificity; D014158:Transcription, Genetic
chemical_list: D012333:RNA, Messenger
references: Clin Infect Dis. 2006 Sep 1;43(5):585-92
references: 16886150
references: J Virol. 1988 Oct;62(10):3684-94
references: 2843669
references: Clin Infect Dis. 2007 Apr 1;44(7):904-10
references: 17342639
references: J Virol. 1984 Feb;49(2):315-8
references: 6319731
references: Genes Dev. 1992 Jun;6(6):1107-19
references: 1592259
references: J Virol. 2002 Dec;76(24):12435-47
references: 12438569
references: J Virol. 2004 Dec;78(23):12929-39
references: 15542645
references: Proc Natl Acad Sci U S A. 2005 Sep 6;102(36):12891-6
references: 16118271
references: J Infect Dis. 2006 Nov 1;194(9):1276-82
references: 17041854
references: Virology. 1961 Jun;14:288-9
references: 13681037
references: J Clin Virol. 2006 Jan;35(1):99-102
references: 16257260
references: Emerg Infect Dis. 2006 May;12(5):862-3
references: 16710957
references: Virology. 2002 Oct 25;302(2):219-23
references: 12441065
references: J Virol. 1988 Oct;62(10):3807-13
references: 2843676
references: J Virol. 2006 Jun;80(11):5482-93
references: 16699028
references: Virology. 1991 Mar;181(1):22-34
references: 1825251
references: Infect Agent Cancer. 2007 Jan 31;2:3
references: 17266760
references: J Infect Dis. 2006 Nov 1;194(9):1197-9
references: 17041844
references: J Virol. 1988 Aug;62(8):2745-54
references: 2839699
references: J Virol. 1986 Dec;60(3):1085-97
references: 3783814
references: Virology. 1973 Jan;51(1):129-37
references: 4734323
references: Emerg Infect Dis. 2006 May;12(5):848-50
references: 16704852
references: J Virol. 1992 Aug;66(8):4686-92
references: 1385833
references: J Infect Dis. 2007 Apr 1;195(7):1038-45
references: 17330795
references: J Virol. 1987 Aug;61(8):2395-406
references: 3599180
references: J Virol. 2006 Jan;80(2):654-62
references: 16378968
references: J Virol. 1987 Nov;61(11):3612-6
references: 2959794
references: Clin Infect Dis. 2006 Aug 1;43(3):283-8
references: 16804840
references: J Clin Microbiol. 2006 Mar;44(3):1132-4
references: 16517912
references: Dev Cell. 2001 Aug;1(2):291-302
references: 11702787
references: J Infect Dis. 2006 Nov 1;194(9):1283-90
references: 17041855
references: Nucleic Acids Res. 1983 Feb 25;11(4):1019-38
references: 6828378
references: J Virol. 1988 Feb;62(2):417-26
references: 3275788
references: J Virol. 1983 Oct;48(1):10-7
references: 6887348