title: Medical exposure to ionising radiation and the risk of brain tumours: Interphone study group, Germany.
abstract: BACKGROUND
  The role of exposure to low doses of ionising radiation in the aetiology of brain tumours has yet to be clarified. The objective of this study was to investigate the association between medically or occupationally related exposure to ionising radiation and brain tumours.
  
  
  METHODS
  We used self-reported medical and occupational data collected during the German part of a multinational case-control study on mobile phone use and the risk of brain tumours (Interphone study) for the analyses.
  
  
  RESULTS
  For any exposure to medical ionising radiation we found odds ratios (ORs) of 0.63 (95% confidence interval (CI)=0.48-0.83), 1.08 (95% CI=0.80-1.45) and 0.97 (95% CI=0.54-1.75) for glioma, meningioma and acoustic neuroma, respectively. Elevated ORs were found for meningioma (OR 2.32, 95% CI: 0.90-5.96) and acoustic neuroma (OR 6.45, 95% CI: 0.62-67.16) for radiotherapy to the head and neck regions.
  
  
  CONCLUSIONS
  We did not find any significant increased risk of brain tumours for exposure to medical ionising radiation.
authors: Institute of Medical Biostatistics, Epidemiology and Informatics, Johannes Gutenberg-University of Mainz, Obere Zahlbacher Strasse 69, 55131 Mainz, Germany. blettner@imbei.uni-mainz.de
authors: Maria
authors: M
authors: Blettner
authors: Brigitte
authors: B
authors: Schlehofer
authors: Florence
authors: F
authors: Samkange-Zeeb
authors: Gabriele
authors: G
authors: Berg
authors: Klaus
authors: K
authors: Schlaefer
authors: Joachim
authors: J
authors: Schüz
mesh_terms: D000328:Adult; D000368:Aged; D001932:Brain Neoplasms / Q000453:epidemiology / Q000209:etiology*; D016022:Case-Control Studies; D040421:Cell Phone; D004574:Electromagnetic Fields / Q000009:adverse effects; D005260:Female; D005858:Germany / Q000453:epidemiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009381:Neoplasms, Radiation-Induced / Q000453:epidemiology / Q000209:etiology*; D016273:Occupational Exposure / Q000009:adverse effects*; D011839:Radiation, Ionizing; D012307:Risk Factors