Growing a living blood vessel: insights for the second hundred years.
Cardiovascular disease continues to be the leading cause of death worldwide, and the prevalence of cardiovascular disease has reached epidemic proportions worldwide. Not surprisingly this has led to an increasing number of vascular procedures annually. Unfortunately, the success of these procedures over time continues to limit their long-term effects. Biomedical engineering approaches to improve upon current prosthetic grafts, developing new prosthetic grafts, and creating tissue engineered blood vessels for clinical application offer hope of improving the durability of vascular interventions and improving patients' treatment for cardiovascular disease.
Brewster
Luke P
LP
Department of Surgery, Loyola University Medical Center, Maywood, IL, USA.
Bufallino
Dominick
D
Ucuzian
Areck
A
Greisler
Howard P
HP
D000818:Animals; D001698:Biomedical Engineering / Q000379:methods*; D001807:Blood Vessel Prosthesis; D019917:Blood Vessel Prosthesis Implantation / Q000379:methods*; D001808:Blood Vessels / Q000473:pathology*; D002196:Capillaries / Q000473:pathology; D002318:Cardiovascular Diseases / Q000628:therapy*; D002454:Cell Differentiation; D018920:Coculture Techniques; D004730:Endothelium, Vascular / Q000473:pathology; D016220:Fibroblast Growth Factor 1 / Q000378:metabolism; D006801:Humans; D023822:Tissue Engineering / Q000379:methods*
D016220:Fibroblast Growth Factor 1
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