Primary ovarian angiosarcoma--review of the literature and report of a case with coexisting chylothorax.
BACKGROUND
Primary ovarian angiosarcoma is a very rare gynaecologic malignancy with poor prognosis and uncertain, up-to-date, treatment options. Its exact diagnosis is challenging for surgeons and difficult for pathologists. There are only a few cases reported in the international literature.


METHODS
We report a case of primary pure ovarian angiosarcoma with coexisting chylothorax which is, to the best of our knowledge, the first reported case. An extensive review of the literature analyzing all clinical and pathological parameters related to this condition is presented.


RESULTS
In spite of all therapeutic efforts, surgical and medical, prognosis of ovarian angiosarcoma remains very poor in most cases.


CONCLUSIONS
Primary ovarian angiosarcoma is a rare and aggressive malignancy. The report of such cases is interesting in order to exchange knowledge and experience, and possibly to further improve our diagnostic and therapeutic capabilities.
Vavilis
D
D
1st Department of Obstetrics and Gynecology, Aristotle University of Thessaloniki, Greece.
Papadopoulos
N
N
Agorastos
T
T
Efstratiou
I
I
Kommoss
F
F
Bontis
I N
IN
D000328:Adult; D002916:Chylothorax / Q000150:complications*; D017809:Fatal Outcome; D005260:Female; D006394:Hemangiosarcoma / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D006801:Humans; D010051:Ovarian Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy