Effects of light on development of mammalian zygotes.
It is generally assumed that light has no effect on the physiology of oocytes, zygotes, or early embryos. Therefore, little or no attention has been paid to lighting conditions during the handling of these cells in vitro. Here we show that cool white fluorescent light, rich in short-wavelength visible light and commonly used in research and clinical laboratories, produces more reactive oxygen species in mouse and hamster zygotes than does warm white fluorescent light. Mouse blastocysts that developed from zygotes shielded from light best developed to term fetuses followed by those exposed to warm white fluorescent light and then by those exposed to cool white fluorescent light. We hypothesized that light is one of the physical factors affecting embryonic environment and that its effects on cultured mammalian zygotes and embryos should not be overlooked.
Takenaka
Manami
M
Graduate School of Comprehensive Scientific Research, Prefectural University of Hiroshima, Shobara, Hiroshima 727-0023, Japan.
Horiuchi
Toshitaka
T
Yanagimachi
Ryuzo
R
D000818:Animals; D017209:Apoptosis / Q000528:radiation effects; D001755:Blastocyst / Q000166:cytology / Q000528:radiation effects; D006224:Cricetinae; D010064:Embryo Implantation; D005260:Female; D005453:Fluorescence; D006801:Humans; D066298:In Vitro Techniques; D008027:Light; D008297:Male; D051379:Mice; D017382:Reactive Oxygen Species / Q000378:metabolism; D013696:Temperature; D015053:Zygote / Q000166:cytology / Q000254:growth & development* / Q000528:radiation effects*
D017382:Reactive Oxygen Species
J Assist Reprod Genet. 2007 Feb-Mar;24(2-3):99-103
17216346
Nat Biotechnol. 1999 Aug;17(8):763-7
10429240
Mol Hum Reprod. 1997 Oct;3(10):919-25
9395266
J Anim Sci. 1968;27 Suppl 1:1-14
5212490
Biol Reprod. 2003 Oct;69(4):1109-17
12773416
Diabetes. 1990 Apr;39(4):471-6
2318348
Fertil Steril. 1988 Dec;50(6):938-44
3203758
Proc Natl Acad Sci U S A. 2004 Apr 20;101(16):5880-5
15079084
Biol Reprod. 2003 Oct;69(4):1371-8
12826584
Hum Reprod. 1998 Apr;13(4):998-1002
9619561
J Exp Zool. 1978 Dec;206(3):365-9
568652
Biol Reprod. 1997 May;56(5):1088-96
9160705
J Reprod Fertil. 1999 Sep;117(1):97-105
10645250
J Reprod Fertil. 1966 Jun;11(3):359-70
5940534
Endocrinology. 2005 May;146(5):2140-1
15833923
Hum Reprod. 2000 Jan;15(1):157-64
10611206
Biol Reprod. 1995 Apr;52(4):709-20
7779992
Proc Natl Acad Sci U S A. 2007 Feb 6;104(6):1745-50
17264211
Development. 2004 Aug;131(15):3727-35
15240554
J Reprod Fertil. 1968 Nov;17(2):399-401
5749384
Reproduction. 2005 Dec;130(6):825-8
16322542
Nature. 1964 Jan 18;201:316-7
14113587
Mol Reprod Dev. 2002 Jan;61(1):67-77
11774377
Biol Reprod. 2000 Jul;63(1):281-93
10859270
J Endocrinol. 1959 May;18(3):292-304
13664852
Mol Reprod Dev. 1992 Nov;33(3):297-302
1449795
Theriogenology. 1992 Dec;38(6):1043-54
16727202
Theriogenology. 2000 Jan 15;53(2):619-26
10735054
Development. 1990 Jun;109(2):501-7
2401209
Biol Reprod. 2003 Oct;69(4):1193-200
12773422
J Reprod Fertil. 1989 Mar;85(2):477-81
2703987
Biol Reprod. 2002 Aug;67(2):534-9
12135892
Biochim Biophys Acta. 2006 Oct;1760(10):1536-44
16905260