Metastasis of lobular breast carcinoma to the cervix.
Breast cancers without previous dissemination occasionally result in hematogenous metastases in gynecologic organs, particularly in the cervix. This case report examines a multimodally treated lobular breast cancer patient who was 52 months later diagnosed with malignancy in the uterus. After a tumor was detected at the endocervical and isthmic part of the uterus, a complete hysterectomy with bilateral salpingo-oophorectomy was carried out. The malignant cells were highly positive for carcino-embrional antigen and gross cystic disease fluid protein-15, sensitive breast cancer markers. In conclusion, as breast carcinoma can metastasize to atypical places (cervix, endometrium, etc.), regular surveillance of patients should include gynecologic control.
Perisić
Dragan
D
Department of Obstetrics and Gynecology, Gornji Milanovac Medical Center, Serbia. perisic@eunet.yu
Jancić
Snezana
S
Kalinović
Dragoslav
D
Cekerevac
Milica
M
D000368:Aged; D001943:Breast Neoplasms / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D018275:Carcinoma, Lobular / Q000473:pathology / Q000556:secondary*; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D002583:Uterine Cervical Neoplasms / Q000556:secondary*