Dynamic kinetic resolution allows a highly enantioselective synthesis of cis-alpha-aminocycloalkanols by ruthenium-catalyzed asymmetric hydrogenation.
Liu
Sheng
S
State Key Laboratory and Institute of Elemento-organic Chemistry, Nankai University, Tianjin 300071, China.
Xie
Jian-Hua
JH
Wang
Li-Xin
LX
Zhou
Qi-Lin
QL
D019900:3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer / Q000138:chemical synthesis / Q000737:chemistry; D000577:Amides / Q000737:chemistry*; D002384:Catalysis; D003516:Cycloparaffins / Q000737:chemistry*; D006865:Hydrogenation; D007700:Kinetics; D015394:Molecular Structure; D012428:Ruthenium / Q000737:chemistry*; D013237:Stereoisomerism
D000577:Amides; D003516:Cycloparaffins; D019900:3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; D012428:Ruthenium