[Central serous corticoid and chorioretinopathy].
Central serous chorioretinopathy (CSC) is a relatively frequent ocular disorder. Its pathophysiology remains however unclear. This disease typically affects young men with type A behaviour within a context of stressful events. Recently, endogenous or exogenous hypercortisolism has been associated with development, prolongation and exacerbation of CSC. Exogenous hypercortisolism has been induced by any route: intravenous, cutaneous, or nasal spray. Some clinical features such as bilaterality of lesions, an atypical form of the presentation can evoke this association. Although a few years ago glucocorticoids were still used as treatment of CSC, experimental and clinical observations suggest that they are contra-indicated in the context of CSC.
Rasquin
F
F
Service d'Ophtalmologie, Hôpital Erasme, Bruxelles. florence.rasquin@erasme.ulb.ac.be
D000308:Adrenocortical Hyperfunction / Q000150:complications; D002825:Chorioretinitis / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology*; D015862:Choroid Diseases / Q000209:etiology; D000075202:Contraindications; D003480:Cushing Syndrome / Q000150:complications; D005260:Female; D007839:Functional Laterality; D005938:Glucocorticoids / Q000009:adverse effects / Q000627:therapeutic use; D006801:Humans; D008297:Male; D012164:Retinal Diseases / Q000209:etiology; D013315:Stress, Psychological / Q000150:complications; D014434:Type A Personality
D005938:Glucocorticoids