Optimization of single-photon response transmission at the rod-to-rod bipolar synapse.
Our ability to see in dim light is limited by the statistics of light absorption in rod photoreceptors and the faithful transmission of the light-evoked signals through the retina. This article reviews the physiological mechanisms at the synapse between rods and rod bipolar cells, the first relay in a pathway that mediates vision near absolute threshold.
Okawa
Haruhisa
H
Zilkha Neurogenetic Institute, University of Southern California, Los Angeles, CA, USA.
Sampath
Alapakkam P
AP
D000818:Animals; D006801:Humans; D017785:Photons; D017661:Receptors, Presynaptic / Q000502:physiology; D051245:Retinal Bipolar Cells / Q000502:physiology*; D017948:Retinal Rod Photoreceptor Cells / Q000502:physiology*; D012684:Sensory Thresholds / Q000502:physiology; D013569:Synapses / Q000502:physiology; D009435:Synaptic Transmission / Q000502:physiology*
D017661:Receptors, Presynaptic