title: [Estimation of indication for living donor liver transplantation in patients with HCV and/or HBV infection].
abstract: We evaluated 78 patients with chronic viral hepatitis for liver transplantation. 51 patients met our original criteria for liver transplantation, and 35 patients of them suffered from hepatocellular carcinoma (HCC). Patients with HCC were significantly older and showed higher prothrombin activity than those without HCC. Eighteen of 35 patients with HCC did not meet the Milan criteria, and they showed lower levels of total bilirubin, Child-Pugh score, and MELD score than those who met the criteria. Theses results indicate that acceptability for transplantation should be evaluated soon after the patients have become candidates for liver transplantation. In Japan, decompensated liver cirrhosis is a necessary condition for the application of public health insurance against liver transplantarion and, in cases with HCC, it is necessary to meet the Milan criteria. Application to liver transplantation should also be considered based on HCC stage such as the UNOS scoring system.
authors: Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
authors: Sawako
authors: S
authors: Inoue
authors: Shusuke
authors: S
authors: Morizono
authors: Shinsaku
authors: S
authors: Yamashita
authors: Yuki
authors: Y
authors: Horikawa
authors: Motoyuki
authors: M
authors: Kohjima
authors: Yuzuru
authors: Y
authors: Miyagi
authors: Tsuyosi
authors: T
authors: Yoshimoto
authors: Kazuhiro
authors: K
authors: Kotoh
authors: Munechika
authors: M
authors: Enjoji
authors: Ryoichi
authors: R
authors: Takayanagi
authors: Yuji
authors: Y
authors: Soejima
authors: Akinobu
authors: A
authors: Taketomi
authors: Tomoharu
authors: T
authors: Yoshizumi
authors: Yoshihiko
authors: Y
authors: Maehara
authors: Makoto
authors: M
authors: Nakamuta
mesh_terms: D006528:Carcinoma, Hepatocellular / Q000601:surgery; D005260:Female; D019694:Hepatitis B, Chronic / Q000601:surgery*; D019698:Hepatitis C, Chronic / Q000601:surgery*; D006801:Humans; D008113:Liver Neoplasms / Q000601:surgery; D016031:Liver Transplantation; D019520:Living Donors; D008297:Male; D008875:Middle Aged