Prevalence of serum antibodies against Bartonella species in the serum of cats with or without uveitis.
Bartonella henselae has been implicated as a causative agent of chronic uveitis in people and in some cats. The objective of this study was to determine whether Bartonella species seroprevalence or titer magnitude varies among cats with uveitis, cats without ocular diseases recorded and healthy cats, while controlling for age and risk of flea exposure based on state of residence. There was no difference in seroprevalence rates or titer magnitude between cats with uveitis and cats with non-ocular diseases. Healthy cats were more likely to be seropositive for Bartonella species than cats with uveitis. The median Bartonella species titer was 1:64 for all groups, although healthy cats were more likely to have higher titers than cats with uveitis and cats with non-ocular disease. The results suggest that serum antibody tests alone cannot be used to document clinical uveitis associated with Bartonella species infection.
Fontenelle
Jennifer P
JP
Department of Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Veterinary Teaching Hospital, Colorado State University, 300 West Drake Road, Fort Collins, CO 80523, United States.
Powell
Cynthia C
CC
Hill
Ashley E
AE
Radecki
Steven V
SV
Lappin
Michael R
MR
D000818:Animals; D000907:Antibodies, Bacterial / Q000097:blood*; D001474:Bartonella Infections / Q000276:immunology / Q000382:microbiology / Q000662:veterinary*; D018416:Bartonella henselae / Q000276:immunology; D002371:Cat Diseases / Q000453:epidemiology* / Q000276:immunology*; D002415:Cats / Q000276:immunology / Q000382:microbiology; D004269:DNA, Bacterial / Q000032:analysis; D004797:Enzyme-Linked Immunosorbent Assay; D005455:Fluorescent Antibody Technique / Q000662:veterinary; D007124:Immunoenzyme Techniques; D016036:Seroepidemiologic Studies; D014605:Uveitis / Q000276:immunology / Q000382:microbiology / Q000662:veterinary*
D000907:Antibodies, Bacterial; D004269:DNA, Bacterial
Am J Ophthalmol. 2000 Sep;130(3):340-9
11020414
J Am Vet Med Assoc. 1992 Oct 1;201(7):1010-6
1429123
J Am Vet Med Assoc. 2004 Nov 1;225(9):1394-8
15552314
J Clin Microbiol. 1995 Jun;33(6):1655-6
7544366
Am J Vet Res. 1999 Aug;60(8):932-6
10451199
Retina. 1998;18(4):348-55
9730179
Am J Ophthalmol. 2000 Sep;130(3):327-34
11020412
J Clin Microbiol. 2004 Feb;42(2):652-9
14766832
DNA Cell Biol. 2003 Jun;22(6):431-40
12906736
J Am Vet Med Assoc. 1999 Apr 15;214(8):1205-7, 1200
10212684
J Vet Intern Med. 1995 Jan-Feb;9(1):39-42
7891361
J Am Vet Med Assoc. 1994 May 15;204(10):1635-8
8050944
J Clin Microbiol. 1995 Sep;33(9):2445-50
7494043
Curr Opin Ophthalmol. 1999 Jun;10(3):209-16
10537781
J Am Vet Med Assoc. 1991 Jan 1;198(1):135-8
1995571
J Feline Med Surg. 2006 Apr;8(2):85-90
16290092
J Am Vet Med Assoc. 1991 Mar 15;198(6):1049-51
1851738
J Infect Dis. 1995 Oct;172(4):1145-9
7561200
J Feline Med Surg. 2002 Jun;4(2):107-10
12027509
Clin Diagn Lab Immunol. 1999 Jul;6(4):558-66
10391863
J Feline Med Surg. 2000 Mar;2(1):61-8
11716593
J Am Anim Hosp Assoc. 2004 Jan-Feb;40(1):6-12
14736899
Am J Public Health. 1993 Dec;83(12):1707-11
8259799
J Clin Microbiol. 2004 Apr;42(4):1420-7
15070983
J Am Vet Med Assoc. 1990 Apr 1;196(7):1116-9
2158494