Thymosin beta4 and Ac-SDKP: tools to mend a broken heart.
Thymosin beta4 - an endogenously occurring 43 amino acid peptide - has recently been shown to possess cardioprotective properties in the setting of acute myocardial infarction. This review focuses on the reported mechanisms of action through which Thymosin beta4 might accomplish this effect and the clinical prospects for its use as a therapeutic agent.
Rossdeutsch
Alex
A
UCL Institute of Child Health, London, UK.
Smart
Nicola
N
Riley
Paul R
PR
D000818:Animals; D002316:Cardiotonic Agents; D006801:Humans; D009203:Myocardial Infarction / Q000188:drug therapy*; D009842:Oligopeptides / Q000627:therapeutic use*; D013947:Thymosin / Q000502:physiology* / Q000627:therapeutic use; D000099201:Thymosin beta(4)
D002316:Cardiotonic Agents; D009842:Oligopeptides; D013947:Thymosin; D000099201:Thymosin beta(4); C058504:goralatide
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