Homocysteine-lowering vitamins and cardiovascular mortality: are they really effective?
In the light of current data obtained from prospective outcome studies, we believe that it is premature to support the use of homocysteine-lowering vitamins including folic acid in patients with established coronary artery disease in order to improve cardiovascular outcomes. We think that future large-scale epidemiological trials with very long-term follow-up periods will probably solve this dilemma.
Celik
Turgay
T
Iyisoy
Atila
A
Yuksel
U Cagdas
UC
Isik
Ersoy
E
D002318:Cardiovascular Diseases / Q000097:blood* / Q000188:drug therapy / Q000401:mortality*; D005492:Folic Acid / Q000627:therapeutic use; D006710:Homocysteine / Q000097:blood*; D006801:Humans; D014815:Vitamins / Q000627:therapeutic use*
D014815:Vitamins; D006710:Homocysteine; D005492:Folic Acid