Clinical presentation and endoscopic management of Dieulafoy's lesions in an urban community hospital.
OBJECTIVE
To identify rates of occurrence, common clinical and endoscopic features, and to review the outcome of endoscopic management of Dieulafoy's lesions in the upper gastrointestinal (GI) tract in an urban community hospital setting.


METHODS
Endoscopic data from esophagogastroduodenoscopies (EGDs), done at Wyckoff Heights Medical Center, Brooklyn, NY between 2000 and 2006 were reviewed to identify patients with Dieulafoy's lesions. Demographic data, medical history, examination findings, lab data, endoscopic findings and details of therapy for patients treated for Dieulafoy's lesions were reviewed retrospectively.


RESULTS
Dieulafoy's lesions were documented to be the cause of bleeding in approximately 1% of patients presenting with upper gastrointestinal bleeding, while they were detected in only 2 patients when the indications for EGDs were different from active GI bleeding. When we analyzed EGDs performed in patients above age 65 years presenting with gastrointestinal bleeding, prevalence of Dieulafoy's lesions approached 10 percent. The most common location of the lesion was the body of stomach (7), followed by the cardia (4) and the esophagus (2). One patient had this lesion in the fundus and one patient in the duodenal apex. All patients were initially treated endoscopically with epinephrine injection, in eight cases heater probe was applied following epinephrine and endoscopic clips were applied in two cases. All but one of the patients did well in near and intermediate term follow-up (average follow-up period of 18 mo). One patient died of multi-organ failure during the same hospital stay. Average length hospital stay was 7 d.


CONCLUSIONS
Community hospital gastroenterologists and endoscopists should be aware that Dieulafoy's lesions are an uncommon cause of upper GI bleeding among elderly patients. Early accurate diagnosis through emergent endoscopy and endoscopic therapy, especially in patients with multiple co-morbid conditions, can be very effective and life saving.
Nagri
Srikrishna
S
Department of Gastroenterology, Brooklyn Hospital Center, Brooklyn, NY 11201, United States. krishna1973@yahoo.com
Anand
Suryanarayan
S
Arya
Yashpal
Y
D000368:Aged; D000369:Aged, 80 and over; D016145:Endoscopy, Digestive System / Q000379:methods*; D005260:Female; D005753:Gastric Mucosa / Q000098:blood supply / Q000473:pathology / Q000601:surgery; D005767:Gastrointestinal Diseases / Q000150:complications* / Q000175:diagnosis* / Q000473:pathology; D006471:Gastrointestinal Hemorrhage / Q000209:etiology* / Q000601:surgery*; D041981:Gastrointestinal Tract / Q000098:blood supply / Q000473:pathology; D006786:Hospitals, Urban; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D016896:Treatment Outcome; D014505:Urban Population
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