title: Coiling of very large and giant basilar tip aneurysms: midterm clinical and angiographic results.
abstract: OBJECTIVE
  The purpose of this study was to report the midterm clinical and angiographic results of coiling of very large (>15 mm) and giant basilar tip aneurysms.
  
  
  METHODS
  Between January 1995 and October 2005, 44 very large and giant basilar tip aneurysms in 44 patients were coiled. There were 13 men (30%) and 31 women (70%) with a mean age of 51.4 years (median, 51 years; range, 34-72 years). Mean aneurysm size was 19.6 mm (range, 15-30 mm). Of 44 aneurysms, 33 (75%) had ruptured. Of 11 unruptured basilar tip aneurysms, 7 were incidentally discovered, 1 was additional to another ruptured aneurysm, and 3 were symptomatic by mass effect.
  
  
  RESULTS
  Procedural mortality was 2/44 (4.6%, 95% confidence interval (CI), 0.4%-16%) and morbidity 1/44 (2.3%, 95% CI, 0.01%-13%). Of 33 patients with ruptured aneurysms, mean clinical follow-up was 5.2 years (range, 0.5-11.5 years). Two patients had a rebleeding from the coiled basilar tip aneurysm leading to death in 1 patient and to dependency in the other patient (annual rebleeding rate, 1.1%) One other patient died 2 years later of progressive brain stem compression. Mean angiographic follow-up in 41 of 42 surviving patients was 3.1 years. Nineteen aneurysms reopened and were coiled for a second time. Of these, 9 repeatedly reopened with time and were repeatedly coiled up to 6 times. Additional treatments were without complications.
  
  
  CONCLUSIONS
  Coiling of very large and giant basilar tip aneurysms is associated with reasonably low morbidity. Although additional treatment during follow-up is frequently necessary, rebleeding is uncommon.
authors: Department of Radiology, St. Elisabeth Ziekenhuis, Tilburg, the Netherlands. radiol@knmg.nl
authors: W J
authors: WJ
authors: van Rooij
authors: M
authors: M
authors: Sluzewski
mesh_terms: D000328:Adult; D000368:Aged; D000792:Angiography; D004621:Embolization, Therapeutic / Q000379:methods*; D005260:Female; D006801:Humans; D002532:Intracranial Aneurysm / Q000000981:diagnostic imaging* / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D016896:Treatment Outcome
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