[Vulvovaginal candidiasis in pregnant women with impaired tolerance for glucose].
OBJECTIVE
To evaluate whether incidence of 50 g glucose challenge test (GCT) and 75 g oral glucose tolerance test (OGTT) is higher in pregnant women with vulvovaginal candidiasis (VVC).


METHODS
A retrospective study of pregnant women with IGGT or GDM who delivered at Peking University First Hospital from Jan 1, 2004 to June 30, 2005 was conducted. The prevalence of VVC and re-infected vulvovaginal candidiasis (RVVC) were determined, and blood glucose concentrations of GGT and OGTT in VVC, RVVC and NVVC groups were compared.


RESULTS
Four hundred and one pregnant women were recruited, of whom 51 had VVC, and 16 had RVVC. The prevalence of VVC was greater among GDM women than among IGGT women (P = 0.014). Glucose concentrations were higher in VVC cases than in NVVC cases at GCT [(9.6 +/- 2.0) vs (9.3 +/- 1.6) mmol/L], OGTT 0 hour [(5.4 +/- 1.1) vs (5.3 +/- 0.9) mmol/L], 1 hour [(11.1 +/- 1.7) vs (11.0 +/- 1.5) mmol/L], 2 hours [(9.4 +/- 1.8) vs (9.2 +/- 1.6) mmol/L], however, there were no statistical differences (P > 0.05). Glucose concentrations were higher in RVVC cases than in NVVC cases at GCT [(10.4 +/- 1.2) vs (9.3 +/- 1.6) mmol/L]; OGTT 0 hour [(5.3 +/- 0.6) vs (5.3 +/- 0.9) mmol/L], 1 hour [(11.4 +/- 1.0) vs (11.0 +/- 1.5) mmol/L]; 2 hours [(9.4 +/- 1.4) vs (9.2 +/- 1.6) mmol/L], but there were no statistical differences (P > 0.05).


CONCLUSIONS
The incidence of VVC is higher in pregnant women with GDM than in pregnant women with GIGT, however, GCT, and OGTT show no statistical differences between women with VVC and those without VVC.
Deng
Qing-Shan
QS
Department of Obstetrics and Gynecology, First Hospital, Peking University, Beijing 100034, China.
Yang
Hui-Xia
HX
D000328:Adult; D001786:Blood Glucose / Q000378:metabolism; D002181:Candidiasis, Vulvovaginal / Q000453:epidemiology* / Q000382:microbiology; D002681:China / Q000453:epidemiology; D016640:Diabetes, Gestational / Q000097:blood / Q000453:epidemiology*; D005260:Female; D018149:Glucose Intolerance / Q000097:blood / Q000453:epidemiology*; D005951:Glucose Tolerance Test; D006801:Humans; D015994:Incidence; D011247:Pregnancy; D011262:Pregnancy Trimester, Second; D015995:Prevalence; D012189:Retrospective Studies; D012307:Risk Factors; D014621:Vagina / Q000382:microbiology
D001786:Blood Glucose