title: The effects of anti-adhesion materials in preventing postoperative adhesion in abdominal cavity (anti-adhesion materials for postoperative adhesions).
abstract: OBJECTIVE
  The purpose of this study was to compare the effects of anti-adhesion materials in postoperative adhesions.
  
  
  METHODS
  Rats were assigned to five groups: Group 1: Control. Group 2: chitin layers were used. Group 3: Na-hyaluronate / carboxymethylcellulose layers were used. Group 4: Na-hyaluronate gel was poured into the abdomen. Group 5: methylprednisolone was injected. The adhesion frequency and grade were scored according to Granat. Blood was taken for Hb, AST, BUN and albumin levels determination.
  
  
  RESULTS
  The adhesion frequencies (right and left) and grades were as follow in Groups; I: 82%, 91%, 2.63 +/- 1.22; II: 8.3%, 25%, 0.58 +/- 0.66; III: 17%, 33%, 1.08 +/- 1.08; IV: 50%, 58%, 1.41 +/- 1.44; V: 50%, 42%, 1.41 +/- 1.50. The adhesion phase in all study groups was found significantly low compared to control group, p < 0.05. No difference was observed among serologic and hematological parameters in all groups.
  
  
  CONCLUSIONS
  All the materials used significantly lowered the adhesion frequency and grade.
authors: Department of General Surgery, Selcuk University Meram Medical Faculty, Konya, Turkey.
authors: Mustafa
authors: M
authors: Sahin
authors: Murat
authors: M
authors: Cakir
authors: Fatih Mehmet
authors: FM
authors: Avsar
authors: Ahmet
authors: A
authors: Tekin
authors: Tevfik
authors: T
authors: Kucukkartallar
authors: Mehmet
authors: M
authors: Akoz
mesh_terms: D034841:Abdominal Cavity / Q000601:surgery*; D000818:Animals; D000893:Anti-Inflammatory Agents / Q000494:pharmacology; D001672:Biocompatible Materials / Q000627:therapeutic use*; D002266:Carboxymethylcellulose Sodium / Q000627:therapeutic use; D002686:Chitin / Q000627:therapeutic use; D004195:Disease Models, Animal; D005260:Female; D006820:Hyaluronic Acid / Q000627:therapeutic use; D008567:Membranes, Artificial; D008775:Methylprednisolone / Q000494:pharmacology* / Q000627:therapeutic use; D010532:Peritoneal Diseases / Q000473:pathology / Q000503:physiopathology / Q000517:prevention & control*; D011183:Postoperative Complications / Q000473:pathology / Q000503:physiopathology / Q000517:prevention & control*; D051381:Rats; D017208:Rats, Wistar; D012720:Severity of Illness Index; D000267:Tissue Adhesions; D014945:Wound Healing / Q000187:drug effects
chemical_list: D000893:Anti-Inflammatory Agents; D001672:Biocompatible Materials; D008567:Membranes, Artificial; D002686:Chitin; D006820:Hyaluronic Acid; D002266:Carboxymethylcellulose Sodium; D008775:Methylprednisolone
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