Lens cells: more than meets the eye.
Lens cells originate from the head ectoderm and differentiate into an avascular organ constituted from two contiguous cell subpopulations of very different morphology. Lens cells, together with corneal cells, are responsible for the transmission and focusing of light onto the retina. Loss of transparency within the lens, via disruption of membrane transport or protein aggregation, results in cataract.
Tholozan
Frederique M D
FM
Integrative Cell Biology Laboratories, Biological and Biomedical Sciences Department, Durham University, DH1 3LE Durham, UK. f.m.d.tholozan@durham.ac.uk
Quinlan
Roy A
RA
D000818:Animals; D002386:Cataract / Q000209:etiology / Q000473:pathology; D002454:Cell Differentiation; D005123:Eye / Q000166:cytology*; D006801:Humans; D007908:Lens, Crystalline / Q000166:cytology* / Q000196:embryology / Q000473:pathology / Q000502:physiology*; D008954:Models, Biological