Left ventricular functional analysis using 64-slice multidetector row computed tomography: comparison with left ventriculography and cardiovascular magnetic resonance.
OBJECTIVE
The progress in computed tomography (CT) has improved temporal resolution and shortened the acquisition time. We compared cardiac function using 64-slice CT with left ventriculography (LVG) and cardiovascular magnetic resonance (CMR).


METHODS
A head-to-head comparison between CT, LVG and CMR was performed in 41 patients. In global LV function, CMR served as the reference. Regional wall motion was compared in a 5-point scoring system.


RESULTS
CT had excellent intra- and interobserver reproducibility. Ejection fraction, end-diastolic and end-systolic volumes by CT were closely correlated with CMR (r = 0.95, 0.96 and 0.98, respectively), while LVG underestimated LV volumes (p < 0.01). The standard deviation of ejection fraction difference between CT and CMR was significantly lower than that between LVG and CMR (p = 0.0015). In regional function, there were good agreements of 94.8% (kappa = 0.82) between CT and LVG and 94.5% (kappa = 0.84) between CT and CMR. The intermethod agreements in mild hypokinesis using CT tended to be lower.


CONCLUSIONS
An excellent correlation was observed between CT and CMR in the LV function over a wide range of heart rates. However, even though 64-slice CT tended to be less sensitive in detecting mild hypokinesis, it still showed excellent concordance in advanced regional abnormalities.
Wu
Yen-Wen
YW
Department of Diagnostic Imaging, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Tadamura
Eiji
E
Kanao
Shotaro
S
Yamamuro
Masaki
M
Okayama
Satoshi
S
Ozasa
Neiko
N
Toma
Masanao
M
Kimura
Takeshi
T
Kita
Toru
T
Marui
Akira
A
Komeda
Masashi
M
Togashi
Kaori
K
D000368:Aged; D005260:Female; D015637:Gated Blood-Pool Imaging; D006331:Heart Diseases / Q000175:diagnosis / Q000000981:diagnostic imaging* / Q000503:physiopathology; D006339:Heart Rate; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009200:Myocardial Contraction; D015588:Observer Variation; D014057:Tomography, X-Ray Computed / Q000379:methods; D016277:Ventricular Function, Left