title: [Persistent pulmonary hypertension in a neonate caused by blood aspiration following vaginal blood loss].
abstract: A preterm neonate, with a gestational age of 30 1/7 weeks, was born after a period of prolonged rupture of the membranes and a retroplacental haematoma causing vaginal bleeding. During admission to the neonatal intensive-care unit, mechanical ventilation was indicated because of acute respiratory failure following blood aspiration, which was causing oxygenation and ventilation problems. Endotracheal surfactant was administered and, because of persistent pulmonary hypertension of the newborn (PPHN), NO-inhalation therapy was started. A quick recovery was seen and two days post partum the patient could be extubated. Blood aspiration may cause acute respiratory problems and PPHN, with quick recovery after effective mechanical ventilation, surfactant and NO-inhalation therapy.
authors: Academisch Ziekenhuis Maastricht, afd. Kindergeneeskunde, Postbus 5800, 6202 AZ Maastricht.
authors: M F
authors: MF
authors: Krüse-Ruijter
authors: L J I
authors: LJ
authors: Zimmermann
mesh_terms: D000280:Administration, Inhalation; D001769:Blood; D001993:Bronchodilator Agents / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D006976:Hypertension, Pulmonary / Q000209:etiology* / Q000628:therapy*; D007231:Infant, Newborn; D007234:Infant, Premature; D015931:Intensive Care, Neonatal; D009569:Nitric Oxide / Q000627:therapeutic use*; D007744:Obstetric Labor Complications; D011247:Pregnancy; D012131:Respiratory Insufficiency / Q000188:drug therapy* / Q000209:etiology; D016896:Treatment Outcome
chemical_list: D001993:Bronchodilator Agents; D009569:Nitric Oxide