title: The distribution and pathological staging of colorectal cancers in ethnic groups.
abstract: BACKGROUND
  There is little data on the distribution and histological staging of colorectal cancer in ethnic groups in the United Kingdom. A study to investigate this was undertaken at a hospital serving a multi-ethnic population.
  
  
  METHODS
  Case analysis from a prospective database of all colorectal cancers between 2000-2004 was performed. Data was recorded on the distribution of cancer, operative procedures and Dukes' staging.
  
  
  RESULTS
  A total of 256 patients (118 females) were diagnosed with colorectal cancer, of whom 214 (83.6%) underwent resection. There were 39 Afro-Caribbeans 66.2 years +/- 12.6 years; mean [age +/- s.d.], 14 Asians 64 years +/- 12.6 years, 34 Mediterraneans 67.7 years +/- 9.9 years and 176 Caucasian British 74.3 years +/- 11.3 years. Right-sided colonic lesions were more frequent in Afro-Caribbeans, whilst left-sided lesions were more frequent in Mediterraneans. The incidence of Dukes'A cancer was high in Mediterraneans whilst Dukes' C cancer was commoner in Caucasians and Afro-Caribbeans.
  
  
  CONCLUSIONS
  Ethnic patients present with colorectal cancer at significantly younger ages. Afro-Caribbeans have significantly more right-sided and Mediterraneans more left-sided cancer. Afro-Caribbean and Caucasian patients present with more advanced cancer compared to Mediterraneans. This has implications on the investigation, as well as screening in ethnic minority patients.
authors: Department of Surgery, North Middlesex University Hospital, Edmonton, London, UK.
authors: Alok
authors: A
authors: Tiwari
authors: Tun Kwan
authors: TK
authors: Yeo
authors: Solon
authors: S
authors: Riris
authors: Mohammed
authors: M
authors: Moghal
authors: Sue
authors: S
authors: Williams
authors: Luke
authors: L
authors: Meleagros
mesh_terms: D000368:Aged; D015179:Colorectal Neoplasms / Q000208:ethnology* / Q000473:pathology*; D005006:Ethnicity; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging