title: Chorioretinal anastomosis after photodynamic therapy for polypoidal choroidal vasculopathy: CRA after PDT for PCV.
abstract: An 80-year-old woman was treated with photodynamic therapy (PDT) to the left eye for polypoidal choroidal vasculopathy (PCV). About 3 months after PDT, her left eye developed a chorioretinal anastomosis with severe atrophy of the retinal pigment epithelium in the macula; visual acuity in this eye was 20/1000. She received a second session of PDT, plus an intravitreal injection of triamcinolone acetonide. About 3 months after the second treatment, the chorioretinal anastomosis was enlarged and the retinal vessels involved in the anastomosis were more dilated. About 1 year after the first PDT, visual acuity in the left eye had stabilized at 20/400. Development of a chorioretinal anastomosis is a distinct possibility following PDT in eyes with PCV, and can lead to poor visual recovery.
authors: Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Sakyo-ku, Kyoto 606-8507, Japan.
authors: Yuko
authors: Y
authors: Yodoi
authors: Akitaka
authors: A
authors: Tsujikawa
authors: Atsushi
authors: A
authors: Otani
authors: Hiroko
authors: H
authors: Aikawa
authors: Nagahisa
authors: N
authors: Yoshimura
mesh_terms: D000369:Aged, 80 and over; D001164:Arteriovenous Fistula / Q000175:diagnosis / Q000209:etiology*; D002829:Choroid / Q000098:blood supply*; D020256:Choroidal Neovascularization / Q000188:drug therapy*; D005260:Female; D005451:Fluorescein Angiography; D005654:Fundus Oculi; D006801:Humans; D010778:Photochemotherapy / Q000009:adverse effects*; D017319:Photosensitizing Agents / Q000009:adverse effects* / Q000627:therapeutic use; D012171:Retinal Vessels / Q000002:abnormalities*; D014792:Visual Acuity
chemical_list: D017319:Photosensitizing Agents
references: Arch Ophthalmol. 2005 Aug;123(8):1149-53
references: 16087856
references: Retina. 1990;10(1):1-8
references: 1693009
references: Graefes Arch Clin Exp Ophthalmol. 2006 Oct;244(10 ):1363-6
references: 16523294
references: Ophthalmology. 2004 Aug;111(8):1576-84
references: 15288991
references: Retina. 1990;10(1):9-17
references: 2343198
references: Ophthalmologe. 2003 Mar;100(3):197-202
references: 12640548
references: Retina. 2007 Mar;27(3):335-41
references: 17460589