Formal synthesis of (+/-)-platensimycin.
A formal total synthesis of (+/-)-platensimycin [(+/-)-1] is reported involving an intramolecular Stetter reaction and a radical cyclization.
Nicolaou
K C
KC
Department of Chemistry and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, USA. kcn@scripps.edu
Tang
Yefeng
Y
Wang
Jianhua
J
D000218:Adamantane / Q000138:chemical synthesis* / Q000737:chemistry; D062365:Aminobenzoates / Q000138:chemical synthesis* / Q000737:chemistry; D000813:Anilides / Q000138:chemical synthesis* / Q000737:chemistry; D000900:Anti-Bacterial Agents / Q000138:chemical synthesis / Q000737:chemistry; D003500:Cyclization; D015394:Molecular Structure
D062365:Aminobenzoates; D000813:Anilides; D000900:Anti-Bacterial Agents; D000218:Adamantane; C510909:platensimycin