Epidural spinal cord stimulation in lower limb ischemia.
Epidural spinal cord stimulation (SCS) has been used as a method to improve microcirculatory blood flow, relieve ischemic pain and reduce amputation rate in patients with severe peripheral arterial occlusive disease (PAOD). In this article, the theories attempting to explain the mechanisms of SCS vasoactive action are presented. Our method of patient screening and our surgical technique for SCS implantation are described. In addition, the various published series reporting on the efficacy of SCS in PAOD are critically reviewed. The contemporary reports demonstrate the efficacy of SCS in ischemic pain relief. In the light of these results and our own experience, we conclude with an appraisal of modern techniques for assessing critical limb ischemia.
Vincenzo
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S
Department of Surgery, Pietro Valdoni, University of Rome La Sapienza, Viale del Policlinico, 00161 Rome, Italy. vincenzo.sciacca@uniromal.it
Kyventidis
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T
D004599:Electric Stimulation Therapy; D004567:Electrodes, Implanted; D006801:Humans; D007511:Ischemia / Q000473:pathology* / Q000628:therapy*; D035002:Lower Extremity / Q000503:physiopathology*; D015201:Meta-Analysis as Topic; D016491:Peripheral Vascular Diseases / Q000150:complications; D013116:Spinal Cord / Q000502:physiology / Q000528:radiation effects*