title: Foundations for directed alkaloid biosynthesis.
abstract: In this issue of Chemistry & Biology, Bernhardt and coworkers [1] assay the functional plasticity of strictosidine synthase, a gateway enzyme in the biosynthetic pathways of monoterpene indole alklaloids, and the downstream operability of the products of strictosidine synthase variants in the larger context of the plant biosynthetic pathways.
authors: Department of Chemistry, Vanderbilt University, 7921 Stevenson Center, Nashville, TN 37235, USA. brian.bachmann@vanderbilt.edu
authors: Brian O
authors: BO
authors: Bachmann
mesh_terms: D019759:Carbon-Nitrogen Lyases / Q000378:metabolism; D002384:Catalysis; D026121:Indole Alkaloids / Q000378:metabolism*; D015202:Protein Engineering; D014748:Vinca Alkaloids / Q000096:biosynthesis
chemical_list: D026121:Indole Alkaloids; D014748:Vinca Alkaloids; C021093:strictosidine; D019759:Carbon-Nitrogen Lyases; C022684:strictosidine synthetase