Iodinane- and metal-free synthesis of N-cyano sulfilimines: novel and easy access of NH-sulfoximines.
The synthesis of N-cyanosulfilimines can readily be achieved by reaction of the corresponding sulfides with cyanogen amine in the presence of a base and NBS or I2 as halogenating agents. Oxidation followed by C-N bond cleavage affords synthetically useful NH-free sulfoximines.
Mancheño
Olga García
OG
Institute of Organic Chemistry, RWTH Aachen University, Landoltweg 1, D-52056 Aachen, Germany.
Bistri
Olivia
O
Bolm
Carsten
C
D003486:Cyanides / Q000737:chemistry*; D007097:Imines / Q000138:chemical synthesis* / Q000737:chemistry; D007455:Iodine / Q000737:chemistry*; D008670:Metals / Q000737:chemistry; D015394:Molecular Structure; D009584:Nitrogen / Q000737:chemistry*; D010091:Oximes / Q000737:chemistry*; D013440:Sulfides / Q000737:chemistry; D013455:Sulfur / Q000737:chemistry*
D003486:Cyanides; D007097:Imines; D008670:Metals; D010091:Oximes; D013440:Sulfides; D013455:Sulfur; D007455:Iodine; D009584:Nitrogen