Peptide fragment intensity statistical modeling.
We present new statistical models of peptide fragment peak intensities that achieve unprecedented accuracy, and we discuss their application to the problem of scoring in database searching or peptide de novo sequencing. The models, made available via open-source computer programs, are very general and can potentially improve any intensity-based scoring.
Colinge
Jacques
J
Research Center for Molecular Medicine of the Austrian Academy of Sciences, Lazarettgasse 19/3, A-1090 Vienna, Austria. jcolinge@cemm.oeaw.ac.at
D015233:Models, Statistical; D010446:Peptide Fragments / Q000737:chemistry*; D053719:Tandem Mass Spectrometry
D010446:Peptide Fragments