title: Monolateral dual kidney transplantation from marginal donors.
abstract: BACKGROUND
  Dual kidney transplantation (DKT) offers a safe way to face the organ shortage with good short-term and medium-term renal function. However, its application is limited by the longer operating time and the risk of surgical complication. This study reviews our results with DKT performed with an ipsilateral technique in terms of graft loss, graft and patient survival rates, and surgical complications.
  
  
  METHODS
  From January 2002 to March 2006, 23 patients underwent DKT through a monolateral Gibson incision with placement of both kidneys.
  
  
  RESULTS
  One primary nonfunction occurred (4%). Delayed graft function was observed in 3 DKT (13.3%). Acute rejection rate was 4.3% (1 patient). All patients are alive at a mean follow-up of 28 months. One-year and 2-year graft survival rates were 100% and 96%, respectively. Mean serum creatinine level at 1-year posttransplantation was 1.3 mg/dL (range, 0.8-2.1 mg/dL). One DKG recipient lost 1 graft, retaining the second normal functioning graft due to ureteral necrosis. The mean hospital stay after transplantation was 15 days (range, 12-34 days).
  
  
  CONCLUSIONS
  Monolateral placement in DKT offers the advantage of a single incision, minimizing the surgical risk. Tailored immunosuppression and careful selection of potential recipients, by excluding those with severe cardiopulmonary pathologies, could significantly improve both patient and graft survival in this group of patients.
authors: Department of Surgery, Transplantation and Advanced Technologies, Organ Transplant Unit, University Hospital of Catania, Catania, Italy. veroux@unict.it
authors: M
authors: M
authors: Veroux
authors: D
authors: D
authors: Corona
authors: M
authors: M
authors: Gagliano
authors: M
authors: M
authors: Macarone
authors: M
authors: M
authors: Sorbello
authors: G
authors: G
authors: Giuffrida
authors: M
authors: M
authors: Cutuli
authors: G
authors: G
authors: Morello
authors: D
authors: D
authors: Vizcarra
authors: A
authors: A
authors: Paratore
authors: P
authors: P
authors: Veroux
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D005500:Follow-Up Studies; D006084:Graft Rejection / Q000453:epidemiology; D006801:Humans; D016030:Kidney Transplantation / Q000379:methods*; D008875:Middle Aged; D014019:Tissue Donors / Q000706:statistics & numerical data*; D016896:Treatment Outcome