[Management of capecitabine-induced hand-foot syndrome by local phytotherapy].
The so-called hand-foot syndrome (HFS) is a dose-limiting side effect with only rare therapeutic options in cancer patients treated with capecitabine (Xeloda). Depending on the intensity of the skin reaction dose reduction, interruption or even the break-off of capecitabine therapy is necessary. We therefore try to describe a new and promising alternative treatment of the hand-foot syndrome, a local therapy with a mixture of herbal medicinal products mainly consisting of hand- and foot baths, and present the promising results of this treatment modality observed in 11 consecutive patients.
Kern
Elisabeth
E
Anstaltsapotheke des Krankenhauses der Barmherzigen Schwestern, Linz, Austria.
Schmidinger
Manuela
M
Locker
Gottfried J
GJ
Kopp
Brigitte
B
D000964:Antimetabolites, Antineoplastic / Q000009:adverse effects*; D020838:Calendula; D000069287:Capecitabine; D003841:Deoxycytidine / Q000009:adverse effects / Q000031:analogs & derivatives*; D005472:Fluorouracil / Q000009:adverse effects / Q000031:analogs & derivatives*; D005533:Foot Dermatoses / Q000139:chemically induced* / Q000188:drug therapy*; D006229:Hand Dermatoses / Q000139:chemically induced* / Q000188:drug therapy*; D006801:Humans; D031168:Matricaria; D008517:Phytotherapy; D027544:Salvia; D016896:Treatment Outcome
D000964:Antimetabolites, Antineoplastic; D003841:Deoxycytidine; D000069287:Capecitabine; D005472:Fluorouracil
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