title: Antioxidant activity and total phenols in different extracts of four Staphylea L. Species.
abstract: Staphylea L. is a deciduous ornamental shrub that possesses significant cytotoxic and antibacterial activity, although the chemical composition of its extracts and the identity of the structures responsible for these biological activities are not yet known. In this study we have determined the total phenolic content in chloroform and ethyl acetate extracts of four Staphylea species: Staphylea colchica Stev., S. elegans Zab., S. holocarpa Hemsl. and S. pinnata L.. The antioxidant potential (DPPH radical and peroxynitrite scavenging activity) of these extracts was also determined and a correlation between the phenolic content and antioxidant activities of the ethyl acetate extracts has been found. Ethyl acetate extracts were more active and one of them, obtained from S. colchica Stev., possessed the highest activity.
authors: Department of Pharmacognosy and Botany, Faculty of Pharmacy, Comenius University, Odbojárov 10, Bratislava, Slovakia. lacikova@fpharm.uniba.sk
authors: Lubica
authors: L
authors: Lacikova
authors: Jan
authors: J
authors: Muselik
authors: Irena
authors: I
authors: Masterova
authors: Daniel
authors: D
authors: Grancai
mesh_terms: D000975:Antioxidants / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D001713:Biphenyl Compounds / Q000037:antagonists & inhibitors / Q000737:chemistry; D005609:Free Radicals / Q000037:antagonists & inhibitors / Q000737:chemistry; D006834:Hydrazines / Q000037:antagonists & inhibitors / Q000737:chemistry; D019684:Magnoliopsida / Q000737:chemistry*; D030421:Peroxynitrous Acid / Q000037:antagonists & inhibitors / Q000737:chemistry; D010636:Phenols / Q000737:chemistry*; D010851:Picrates; D010936:Plant Extracts / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D013045:Species Specificity
chemical_list: D000975:Antioxidants; D001713:Biphenyl Compounds; D005609:Free Radicals; D006834:Hydrazines; D010636:Phenols; D010851:Picrates; D010936:Plant Extracts; D030421:Peroxynitrous Acid; C004931:1,1-diphenyl-2-picrylhydrazyl
references: Phytother Res. 2000 Dec;14(8):601-3
references: 11113995
references: Life Sci. 2004 Mar 12;74(17):2157-84
references: 14969719
references: Phytother Res. 2001 Feb;15(1):22-5
references: 11180517
references: Life Sci. 2005 May 6;76(25):2981-93
references: 15820508
references: J Trace Elem Med Biol. 2004;18(2):155-61
references: 15646262