Prevention of primary bacteraemia.
This overview provides information on recent advances in the prevention of primary bacteraemia, commonly defined as bloodstream infection without a documented source of infection, but including those resulting from an intravenous or arterial line infection. The potential to prevent community-acquired, primary bacteraemia is still limited and may be targeted mainly at vaccines for high-risk groups. In contrast, the prevention of catheter-related bacteraemia has seen substantial progress within the last 10 years. Consequently, intravascular device-related bacteraemia has become largely preventable under routine working conditions. Independent of the use of antibiotic-coated catheters, the implementation of clinical pathways and multimodal preventive strategies directed at several risk factors of catheter-related bacteraemia is a successful strategy to reduce this potentially life-threatening infection and deserves future health services research.
Juan-Torres
Antoni
A
Division of Infectious Diseases, Geneva University Hospitals, Geneva, Switzerland.
Harbarth
Stephan
S
D016470:Bacteremia / Q000517:prevention & control*; D002408:Catheters, Indwelling / Q000009:adverse effects; D017714:Community-Acquired Infections / Q000517:prevention & control; D003428:Cross Infection / Q000517:prevention & control; D006801:Humans; D017053:Infection Control / Q000379:methods; D014612:Vaccines / Q000008:administration & dosage / Q000276:immunology
D014612:Vaccines