title: Subunit assembly of plant lectins.
abstract: Lectins are a structurally diverse group of carbohydrate recognizing proteins that are involved in various biological processes and exhibit substantial structural diversity. Interestingly, in spite of having varied carbohydrate-binding specificities, they show modest variation in their secondary and tertiary structure. However, very similar tertiary folds give rise to a range of quaternary structures by simply varying the mutual orientations of the subunits involved. The variety in the quaternary structure generates multivalency in sugar specificities among lectins along with the requisite surface topology to allow for unobstructed recognition events.
authors: Molecular Biophysics Unit, Indian Institute of Science, Bangalore 560012, India. sinhas@mbu.iisc.ernet.in
authors: Sharmistha
authors: S
authors: Sinha
authors: Garima
authors: G
authors: Gupta
authors: Mamannamana
authors: M
authors: Vijayan
authors: Avadhesha
authors: A
authors: Surolia
mesh_terms: D023181:Antimicrobial Cationic Peptides / Q000737:chemistry; D007887:Fabaceae / Q000737:chemistry; D008958:Models, Molecular; D037121:Plant Lectins / Q000737:chemistry*; D020836:Protein Structure, Quaternary; D017434:Protein Structure, Tertiary; D021122:Protein Subunits
chemical_list: D023181:Antimicrobial Cationic Peptides; D037121:Plant Lectins; D021122:Protein Subunits; C045875:hevein