Counterpoint: prostate cancer life expectancy can not be accurately predicted from currently available tools.
A large and growing percentage of prostate cancers are diagnosed among men of advanced age. Current guidelines stratify treatment recommendations based on life expectancy; therefore, accurate determination of life expectancy is essential. Evidence shows that patient-related factors, including age, comorbidities, and functional status, are critical determinants of life expectancy. Equally strong evidence supports tumor-related factors, including Gleason score, tumor stage, and prostate-specific antigen, and efficacy of treatment. Currently, no available tools comprehensively consider all pertinent factors in determining life expectancy.
McCloskey
Susan A
SA
Department of Radiation Medicine, Roswell Park Cancer Institute, Buffalo, New York 14263, USA.
Kuettel
Michael R
MR
D006304:Health Status; D006801:Humans; D008017:Life Expectancy; D008297:Male; D008403:Mass Screening / Q000592:standards / Q000706:statistics & numerical data*; D017430:Prostate-Specific Antigen / Q000097:blood*; D011471:Prostatic Neoplasms / Q000175:diagnosis / Q000401:mortality* / Q000517:prevention & control; D015996:Survival Rate
D017430:Prostate-Specific Antigen