title: Clinical investigation of the transient evoked otoacoustic emission test in Crimean-Congo hemorrhagic fever.
abstract: OBJECTIVE
  The aim of this study was to investigate cochlear damage in Crimean-Congo hemorrhagic fever (CCHF) infection.
  
  
  METHODS
  Thirty-two CCHF patients (study group) and 13 healthy people (controls) were included in the study. CCHF patients were also grouped for the presence of fever. CCHF was diagnosed with the presence of CCHF virus-specific IgM antibody or CCHF virus (CCHFV) antigen by ELISA. Cochlear damage was determined by a 'fail' in the transient evoked otoacoustic emission (TEOAE) test.
  
  
  RESULTS
  The proportion of TEOAE test 'fail' results in the CCHF patients was significantly higher than in the control group (p<0.05). We found no increase in the proportion of TEOAE test 'fail' results related to fever in the study group.
  
  
  CONCLUSIONS
  CCHF disease damages cochlear function regardless of fever.
authors: Department of Infectious Diseases and Clinical Microbiology, Cumhuriyet University School of Medicine, Sivas 58140, Turkey. enginay@cumhuriyet.edu.tr
authors: Aynur
authors: A
authors: Engin
authors: Altan
authors: A
authors: Yildirim
authors: Tanfer
authors: T
authors: Kunt
authors: Mehmet
authors: M
authors: Bakir
authors: Ilyas
authors: I
authors: Dokmetas
authors: Levent
authors: L
authors: Ozdemir
mesh_terms: D000328:Adult; D003051:Cochlea / Q000503:physiopathology*; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006319:Hearing Loss, Sensorineural / Q000821:virology*; D003225:Hemorrhagic Fever Virus, Crimean-Congo / Q000302:isolation & purification; D006479:Hemorrhagic Fever, Crimean / Q000150:complications* / Q000821:virology; D006801:Humans; D008297:Male; D008875:Middle Aged; D017084:Otoacoustic Emissions, Spontaneous; D011446:Prospective Studies; D014421:Turkey