title: Clinical characteristics of dementia associated with argyrophilic grain disease.
abstract: OBJECTIVE
  We aimed at characterizing the clinical features of dementia associated with argyrophilic grain disease (AgD).
  
  
  METHODS
  Relatives or close friends of 24 individuals with autopsy-confirmed AgD and 29 patients with autopsy-confirmed Alzheimer's disease (AD) were administered a novel Retrospective Dementia Inventory to assess the cognitive, behavioral and affective symptoms of the deceased patients.
  
  
  RESULTS
  AgD patients showed less severe impairments in memory, language, attention and executive function than AD patients.
  
  
  CONCLUSIONS
  Compared to AD patients, individuals suffering from AgD appear to present with comparable deficits in behavior and affect but relatively spared cognitive functioning.
authors: Memory Clinic -- Neuropsychology Center, University Hospital Basel, Basel, Switzerland.
authors: Gertrud M
authors: GM
authors: Steuerwald
authors: Thomas P
authors: TP
authors: Baumann
authors: Kirsten I
authors: KI
authors: Taylor
authors: Michael
authors: M
authors: Mittag
authors: Heiner
authors: H
authors: Adams
authors: Markus
authors: M
authors: Tolnay
authors: Andreas U
authors: AU
authors: Monsch
mesh_terms: D000339:Affect / Q000502:physiology; D000368:Aged; D000369:Aged, 80 and over; D001519:Behavior / Q000502:physiology; D001921:Brain / Q000473:pathology; D003071:Cognition / Q000502:physiology; D003704:Dementia / Q000209:etiology / Q000473:pathology / Q000523:psychology*; D018450:Disease Progression; D005260:Female; D006801:Humans; D008297:Male; D019636:Neurodegenerative Diseases / Q000473:pathology / Q000523:psychology*; D009483:Neuropsychological Tests; D010551:Personality; D011569:Psychiatric Status Rating Scales; D011597:Psychomotor Performance / Q000502:physiology; D016875:tau Proteins / Q000502:physiology*
chemical_list: D016875:tau Proteins