Automatic brachytherapy seed placement under MRI guidance.
The paper presents a robotic method of performing low dose rate prostate brachytherapy under magnetic resonance imaging (MRI) guidance. The design and operation of a fully automated MR compatible seed injector is presented. This is used with the MrBot robot for transperineal percutaneous prostate access. A new image-registration marker and algorithms are also presented. The system is integrated and tested with a 3T MRI scanner. Tests compare three different registration methods, assess the precision of performing automated seed deployment, and use the seeds to assess the accuracy of needle targeting under image guidance. Under the ideal conditions of the in vitro experiments, results show outstanding image-guided needle and seed placement accuracy.
Patriciu
Alexandru
A
Urology Department, URobotics Laboratory, The Johns Hopkins University School of Medicine, Baltimore, MD 21224, USA.
Petrisor
Doru
D
Muntener
Michael
M
Mazilu
Dumitru
D
Schär
Michael
M
Stoianovici
Dan
D
D000465:Algorithms; D001918:Brachytherapy / Q000295:instrumentation* / Q000379:methods*; D006801:Humans; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D007267:Injections / Q000379:methods*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D019919:Prosthesis Implantation / Q000379:methods*; D012371:Robotics / Q000379:methods*
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