title: Apparent diffusion coefficient of subcutaneous epidermal cysts in the head and neck comparison with intracranial epidermoid cysts.
abstract: OBJECTIVE
  Subcutaneous epidermal cysts and intracranial epidermoid cysts are pathologically identical. Although diffusion-weighted imaging (DWI) studies of intracranial epidermoid cysts have been numerously reported, those of subcutaneous epidermal cysts have not been sufficiently investigated. Our hypothesis for this study is that the apparent diffusion coefficient (ADC) values of subcutaneous epidermal cysts and intracranial epidermoid cysts are not different. This study was intended to evaluate the ADC of subcutaneous epidermal cysts of the head and neck in comparison with that of intracranial epidermoid cysts.
  
  
  METHODS
  The MR studies were performed in 14 patients with head and neck subcutaneous epidermal cysts and 10 patients with intracranial epidermoid cysts using line scan DWI (LSDWI). The ADC was measured and compared between the two types of cyst.
  
  
  RESULTS
  The ADC values (mean +/- SD) were 0.81 +/- 0.14 x 10(-3) mm(2)/s in subcutaneous epidermal cysts and 1.06 +/- 0.12 x 10(-3) mm(2)/s in intracranial epidermoid cysts. A significant difference was found in ADC values between the two types (P = .0019).
  
  
  CONCLUSIONS
  Our preliminary study has shown that the ADC provides useful information regarding tissue characterization of subcutaneous epidermal cysts. However, the ADC of subcutaneous epidermal cysts was significantly lower than that of intracranial epidermoid cysts.
authors: Department of Radiology, Mie University School of Medicine, 2-174 Edobashi, Tsu, Mie 514-8507, Japan.
authors: Chiori
authors: C
authors: Suzuki
authors: Masayuki
authors: M
authors: Maeda
authors: Akihiko
authors: A
authors: Matsumine
authors: Toshio
authors: T
authors: Matsubara
authors: Waro
authors: W
authors: Taki
authors: Stephan E
authors: SE
authors: Maier
authors: Kan
authors: K
authors: Takeda
mesh_terms: D001927:Brain Diseases / Q000175:diagnosis*; D003937:Diagnosis, Differential; D038524:Diffusion Magnetic Resonance Imaging / Q000379:methods*; D004814:Epidermal Cyst / Q000175:diagnosis*; D005260:Female; D006257:Head / Q000473:pathology; D006801:Humans; D007090:Image Interpretation, Computer-Assisted / Q000379:methods; D008297:Male; D008875:Middle Aged; D009333:Neck / Q000473:pathology; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D012871:Skin Diseases / Q000175:diagnosis*