Safety profile of treatment in diabetic peripheral neuropathic pain.
New treatment options for diabetic peripheral neuropathic pain (DPNP) have recently been developed, including two Food and Drug Administration (FDA) approved agents, duloxetine and pregabalin. As clinicians face a broader spectrum of efficacious treatments, side-effect profiles play an increasingly important role in the development of a pain management regimen. In this article we review the safety profile of agents commonly used in the treatment of DPNP.
Robinson-Papp
Jessica
J
Mount Sinai School of Medicine, New York, New York, USA. Jessica.robinson-papp@mssm.edu
Simpson
David M
DM
D000287:Administration, Topical; D000700:Analgesics / Q000627:therapeutic use; D000779:Anesthetics, Local / Q000008:administration & dosage / Q000627:therapeutic use; D000927:Anticonvulsants / Q000009:adverse effects* / Q000627:therapeutic use*; D000928:Antidepressive Agents / Q000009:adverse effects* / Q000627:therapeutic use*; D018687:Antidepressive Agents, Second-Generation / Q000627:therapeutic use; D000929:Antidepressive Agents, Tricyclic / Q000627:therapeutic use; D002211:Capsaicin / Q000008:administration & dosage / Q000627:therapeutic use; D003511:Cyclohexanols / Q000627:therapeutic use; D003929:Diabetic Neuropathies / Q000150:complications*; D000068736:Duloxetine Hydrochloride; D006801:Humans; D010146:Pain / Q000188:drug therapy* / Q000209:etiology*; D000069583:Pregabalin; D013876:Thiophenes / Q000009:adverse effects* / Q000627:therapeutic use*; D000069470:Venlafaxine Hydrochloride; D005680:gamma-Aminobutyric Acid / Q000009:adverse effects / Q000031:analogs & derivatives* / Q000627:therapeutic use
D000700:Analgesics; D000779:Anesthetics, Local; D000927:Anticonvulsants; D000928:Antidepressive Agents; D018687:Antidepressive Agents, Second-Generation; D000929:Antidepressive Agents, Tricyclic; D003511:Cyclohexanols; D013876:Thiophenes; D000069583:Pregabalin; D005680:gamma-Aminobutyric Acid; D000069470:Venlafaxine Hydrochloride; D000068736:Duloxetine Hydrochloride; D002211:Capsaicin