Prevalence and long-term effects of occult hepatitis B virus infection in HIV-infected women.
Occult hepatitis B virus (HBV) infection is of concern in human immunodeficiency virus (HIV)-infected persons. We observed that 2% of 400 HIV-infected women with antibodies to hepatitis B core antigen alone had occult HBV infection (i.e., detectable HBV DNA in the absence of HBV surface antigen). CD4 cell counts of <200 cells/mm3 were more common among occult HBV-infected women than among those without occult HBV infection. Aminotransferase levels did not appear to be associated with being positive for HBV DNA.
Tsui
Judith I
JI
Department of Medicine, University of California-San Francisco, San Francisco, CA, USA.
French
Audrey L
AL
Seaberg
Eric C
EC
Augenbraun
Michael
M
Nowicki
Marek
M
Peters
Marion
M
Tien
Phyllis C
PC
D000328:Adult; D018791:CD4 Lymphocyte Count; D004279:DNA, Viral / Q000235:genetics; D005260:Female; D015658:HIV Infections / Q000150:complications*; D006509:Hepatitis B / Q000150:complications / Q000453:epidemiology*; D006510:Hepatitis B Antibodies / Q000276:immunology; D006512:Hepatitis B Core Antigens / Q000276:immunology; D006515:Hepatitis B virus / Q000235:genetics / Q000276:immunology / Q000472:pathogenicity*; D006801:Humans; D008875:Middle Aged; D015995:Prevalence; D011446:Prospective Studies; D013997:Time Factors; D014481:United States / Q000453:epidemiology
D004279:DNA, Viral; D006510:Hepatitis B Antibodies; D006512:Hepatitis B Core Antigens
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