Angioedema, lymphoproliferative disorder and angiotensin-converting enzyme inhibitors: masking of diagnosis by corticosteroids.
Angioedema is a relatively common clinical disorder. Although most cases are idiopathic, the use of angiotensin-converting enzyme inhibitors is a well recognized cause of angioedema and a further rare but important diagnostic consideration is acquired C1 inhibitor deficiency. We discuss the diagnosis of C1 inhibitor deficiency in angioedema, with reference to a case in which the diagnosis was initially masked by the use of corticosteroids, which normalized the C1 inhibitor level.
Hissaria
P
P
Division of Immunology and Allergy, Royal Adelaide Hospital, Adelaide, South Australia, Australia. pravin.hissaria@imvs.sa.gov.au
Lim
S-W
SW
Hui
C-H
CH
Gillis
D
D
Kette
F
F
Smith
W
W
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use*; D000368:Aged; D000799:Angioedema / Q000175:diagnosis* / Q000188:drug therapy; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008232:Lymphoproliferative Disorders / Q000175:diagnosis* / Q000188:drug therapy
D000305:Adrenal Cortex Hormones; D000806:Angiotensin-Converting Enzyme Inhibitors