title: Fluoroscopic-guided intradiscal oxygen-ozone injection therapy for thoracolumbar intervertebral disc herniations in dogs.
abstract: BACKGROUND
  To investigate the effect of oxygen-ozone (O2-O3) injection on thoracolumbar intervertebral disc herniation (IVDH) in dogs.
  
  
  METHODS
  Ten herniated discs of five dogs were treated with percutaneous injection of an O2-O3 gas mixture with O3 concentration of 32 microg/microl intradiscally (1.5-2 microl) under fluoroscopy guidance.
  
  
  RESULTS
  Five weeks after treatment, the mean size of herniated discs was measured by computed tomography and showed significant reduction of disc volumes in all animals (8.8%+/-3.82%). The degree of shrinkage was negatively linearly correlated with disc mineralization (correlation coefficient=-0.636) and statistically significant at p<0.05. All five dogs regained their gait function and none recurred.
  
  
  CONCLUSIONS
  We conclude that intradiscal O2-O3 injection can decompress affected discs by disc shrinkage.
authors: Department of Veterinary Surgery, College of Veterinary Medicine, Chungbuk National University, Chungbuk, 361-763, Republic of Korea.
authors: Hyun-Jung
authors: HJ
authors: Han
authors: Joon-Young
authors: JY
authors: Kim
authors: Ha-Young
authors: HY
authors: Jang
authors: Bora
authors: B
authors: Lee
authors: Jung-Hee
authors: JH
authors: Yoon
authors: Sang-Keun
authors: SK
authors: Jang
authors: Seok Hwa
authors: SH
authors: Choi
authors: Soon-Wuk
authors: SW
authors: Jeong
mesh_terms: D000818:Animals; D002114:Calcinosis / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000662:veterinary; D004285:Dogs; D005471:Fluoroscopy; D005500:Follow-Up Studies; D015552:Injections, Intralesional; D007405:Intervertebral Disc Displacement / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000662:veterinary*; D008159:Lumbar Vertebrae; D010100:Oxygen / Q000008:administration & dosage*; D010126:Ozone / Q000008:administration & dosage*; D013904:Thoracic Vertebrae; D016896:Treatment Outcome
chemical_list: D010126:Ozone; D010100:Oxygen