title: Spontaneous splenic rupture in two patients with hematologic malignancy.
abstract: BACKGROUND
  Spontaneous splenic rupture (SSR) is a very rare complication described in several hundred patients, mainly as case reports. It is defined as a splenic rupture without antecedent injury. The authors of the present paper describe the only two SSR cases diagnosed at the Hemato-oncology department, coincidentally in one year.
  
  
  METHODS
  The first patient was admitted to hospital because of planned chemotherapy for relapsed hairy cell leukemia. The second was directed to the Hemato-oncology outpatient department because of anemia and painful splenomegaly diagnosed by a physician. The diagnose of hematologic malignancy (diffuse large B-cell lymphoma) was determined subsequently on the basis of histological examination of the spleen.
  
  
  CONCLUSIONS
  It is necessary to consider SSR not only in patients with known diagnosis of malignant disease but in the patients with negative anamnesis, too. The aim of the paper is to draw attention to the existence of this complication.
authors: Department of Hemato-oncology, Faculty of Medicine and Dentistry, Palacky University, University Hospital Olomouc, Czech Republic. tomast123@seznam.cz
authors: Tomas
authors: T
authors: Szotkowski
authors: Romana
authors: R
authors: Szotkowska
authors: Zuzana
authors: Z
authors: Pikalova
authors: Tomas
authors: T
authors: Tichy
authors: Patrik
authors: P
authors: Flodr
authors: Martin
authors: M
authors: Tichy
authors: Dana
authors: D
authors: Houserkova
authors: Vladimir
authors: V
authors: Benysek
authors: Nora
authors: N
authors: Zlamalova
authors: Vaclav
authors: V
authors: Ruzicka
authors: Karel
authors: K
authors: Indrak
mesh_terms: D000328:Adult; D006801:Humans; D007943:Leukemia, Hairy Cell / Q000150:complications*; D016403:Lymphoma, Large B-Cell, Diffuse / Q000150:complications*; D008297:Male; D008875:Middle Aged; D012422:Rupture, Spontaneous; D013161:Splenic Rupture / Q000209:etiology*