Visual manifestations of craniofrontonasal dysplasia.
In this sample of craniofrontonasal dysplasia, a 44.4% prevalence of visual impairment was observed, with more than half being due to potentially correctable causes of visual loss, including amblyopia and anisometropia. High prevalences of strabismus (88.9%) and V-pattern (55.5%) in craniofrontonasal dysplasia were also demonstrated. All three patients who underwent strabismus surgery showed improvement in ocular alignment postoperatively. This group needs regular eye examinations to assess for visual impairment and provide timely intervention for modifiable causes of visual loss.
Tay
Tien
T
Department of Ophthalmology, The Childrens Hospitalat Westmead, Sydney, Australia.
Martin
Frank
F
Rowe
Neil
N
Johnson
Kim
K
Poole
Michael
M
Tan
Kimberley
K
Kennedy
Ian
I
Gianoutsos
Mark
M
D001315:Australia / Q000453:epidemiology; D002648:Child; D002675:Child, Preschool; D003394:Craniofacial Dysostosis / Q000150:complications*; D003398:Craniosynostoses / Q000150:complications*; D005260:Female; D005624:Frontal Bone / Q000002:abnormalities*; D006801:Humans; D007223:Infant; D008297:Male; D009295:Nasal Bone / Q000002:abnormalities*; D015995:Prevalence; D011379:Prognosis; D012029:Refraction, Ocular; D012189:Retrospective Studies; D013285:Strabismus / Q000453:epidemiology / Q000209:etiology; D014786:Vision Disorders / Q000453:epidemiology / Q000209:etiology*