Palladium-catalyzed silylation of aryl chlorides with hexamethyldisilane.
A method for the palladium-catalyzed silylation of aryl chlorides has been developed. The method affords desired product in good yield, is tolerant of a variety of functional groups, and provides access to a wide variety of aryltrimethylsilanes from commercially available aryl chlorides. Additionally, a one-pot procedure that converts aryl chlorides into aryl iodides has been developed.
McNeill
Eric
E
Department of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.
Barder
Timothy E
TE
Buchwald
Stephen L
SL
D001554:Benzene / Q000737:chemistry; D002384:Catalysis; D002712:Chlorides / Q000737:chemistry*; D004583:Electrons; D007455:Iodine / Q000737:chemistry; D008024:Ligands; D015394:Molecular Structure; D010165:Palladium / Q000737:chemistry*; D012821:Silanes / Q000737:chemistry*
D002712:Chlorides; D008024:Ligands; D012821:Silanes; C520781:hexamethyldisilane; D010165:Palladium; D007455:Iodine; D001554:Benzene