title: Effect of polymerization degree of calcium polyphosphate on its microstructure and in vitro degradation performance.
abstract: Preparation, characterization and in vitro study of a series of calcium polyphosphate (CPP) with different polymerization degree were reported. A series of CPP with different polymerization degree were prepared by controlling calcining time. Average polymerization degree was analyzed by liquid state 31P nuclear magnetic resonance (NMR). The microstructure was observed by scanning electric microscope (SEM). X-ray diffraction (XRD) analysis was used to demonstrate that polymerization degree would not affect the crystal system and space group of CPP. The results showed that polymerization degree increased with the increase of calcining time. Degradation studies were performed during 32 days in physiological saline solution (aqueous solution, 0.9 wt.%NaCl) to assess the effect of polymerization degree on the degradation velocity of the samples. It was also shown that the degradation velocity of CPP (polymerization degree=13) doubles than another two samples (polymerization degree=9,19). The results in the present study may be able to provide some fundamental data for controlling CPP degradation.
authors: Department of Polymer Science and Engineering, Sichun University, Chengdu 610065, China.
authors: Yu Long
authors: YL
authors: Ding
authors: Yuan Wai
authors: YW
authors: Chen
authors: Ying Jie
authors: YJ
authors: Qin
authors: Guo Qi
authors: GQ
authors: Shi
authors: Xi Xun
authors: XX
authors: Yu
authors: C X
authors: CX
authors: Wan
mesh_terms: D020341:Absorbable Implants; D002130:Calcium Phosphates / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D008422:Materials Testing; D049329:Nanostructures; D011108:Polymers / Q000737:chemistry*; D011208:Powders; D013057:Spectrum Analysis; D014961:X-Ray Diffraction
chemical_list: D002130:Calcium Phosphates; D011108:Polymers; D011208:Powders
references: Biomaterials. 2005 Dec;26(35):7276-85
references: 16024076
references: Science. 2002 Feb 8;295(5557):1014-7
references: 11834817
references: J Biomed Mater Res. 2001 Sep 15;56(4):504-15
references: 11400128
references: Tissue Eng. 2000 Aug;6(4):383-99
references: 10992434
references: Biomaterials. 2005 Jul;26(21):4486-94
references: 15701378
references: Biomaterials. 2002 May;23(9):2063-70
references: 11996048
references: Biomaterials. 2001 May;22(9):963-72
references: 11311015
references: Int Endod J. 2006 Jun;39(6):477-83
references: 16674743
references: Biomaterials. 2006 Mar;27(8):1277-86
references: 16143392
references: J Biomed Mater Res. 2002 Sep 5;61(3):482-92
references: 12115474
references: Biomaterials. 2003 Nov;24(26):4761-70
references: 14530073
references: Biomaterials. 2006 Aug;27(22):4120-31
references: 16564568