Tumour banking: the Spanish design.
In the last decade the technical advances in high throughput techniques to analyze DNA, RNA and proteins have had a potential major impact on prevention, diagnosis, prognosis and treatment of many human diseases. Key pieces in this process, mainly thinking about the future, are tumour banks and tumour bank networks. To face these challenges, diverse suitable models and designs can be developed. The current article presents the development of a nationwide design of tumour banks in Spain based on a network of networks, specially focusing on its harmonization efforts mainly regarding technical procedures, ethical requirements, unified quality control policy and unique sample identification. We also describe our most important goals for the next years. This model does not correspond to a central tumour bank, but to a cooperative and coordinated network of national and regional networks. Independently from the network in which it is included, sample collections reside in their original institution, where it can be used for further clinical diagnosis, teaching and research activities of each independent hospital. The herein described 'network of networks' functional model could be useful for other countries and/or international tumour bank activities.
Morente
M M
MM
Tumour Bank Unit, Molecular Pathology Programme, Spanish National Cancer Centre, Madrid, Spain. mmorente@cnio.es
de Alava
E
E
Fernandez
P L
PL
D000818:Animals; D045744:Cell Line, Tumor; D003299:Cooperative Behavior; D004195:Disease Models, Animal; D006801:Humans; D008495:Medical Oncology / Q000379:methods*; D009369:Neoplasms / Q000473:pathology*; D013030:Spain; D014015:Tissue Banks / Q000458:organization & administration* / Q000639:trends