title: [Propofol does not induce retrograde amnesia at the hypnotic dose].
abstract: BACKGROUND
  We evaluated retrograde amnesic effects of propofol at the hypnotic dose on 28 healthy medical personnel volunteers (17 men, 11 women).
  
  
  METHODS
  Explicit memory function was measured after the emergence from bolus infusion of propofol 2 mg x kg(-1); how one could answer the correct number and symbol of 5 playing cards which he had picked up randomly and intentionally memorized before induction? As control, one also took the same test during working hour without any drugs.
  
  
  RESULTS
  After infusion of propofol, the rate of correct answers was 96.4 +/- 9.1% and in control, it was 92.1 +/- 18.3% (P = 0.297142). There was no significant difference among two situations.
  
  
  CONCLUSIONS
  These results suggest that propofol dose not induce retrograde amnesia at hypnotic dose.
authors: Department of Anesthesiology, Hanyu General Hospital, Hanyu 348-8505.
authors: Kazuyoshi
authors: K
authors: Hashimoto
authors: Takayuki
authors: T
authors: Okada
authors: Norimasa
authors: N
authors: Seo
mesh_terms: D000328:Adult; D000648:Amnesia, Retrograde / Q000139:chemically induced; D005260:Female; D006801:Humans; D006993:Hypnotics and Sedatives / Q000008:administration & dosage* / Q000009:adverse effects*; D008297:Male; D008568:Memory / Q000187:drug effects; D008875:Middle Aged; D015742:Propofol / Q000008:administration & dosage* / Q000009:adverse effects*
chemical_list: D006993:Hypnotics and Sedatives; D015742:Propofol