Familial occurrence of gestational hypertensive disorders in a Brazilian population.
OBJECTIVE
To verify the occurrence of preeclampsia/eclampsia (PE/E) or gestational hypertension (GH) in first-degree relatives of Brazilian pregnant women.


METHODS
A total of 485 women were enrolled in the study, and 226 were selected (75 with PE/E, 49 with GH, and 102 women with normal pregnancies). Statistical analysis was performed using Fisher's exact test.


RESULTS
The frequency of families with mothers and/or sisters with PE/E was higher among the PE/E group compared to the GH and the control groups, and was statistically significant (p < 0.05).


CONCLUSIONS
Women with PE/E have more female first-degree relatives with PE/E as observed in a Brazilian population.
Araujo
F M
FM
Department of Obstetrics and Gynecology, University Hospital of Medicine School of Ribeirão Preto, University of São Paulo, Ribeirão Preto, SP, Brazil. francielle@genbov.fmrp.usp.br
Duarte
G
G
Nomelini
J
J
Lôbo
R B
RB
Ramos
E S
ES
D001938:Brazil; D005190:Family; D005260:Female; D006801:Humans; D046110:Hypertension, Pregnancy-Induced / Q000235:genetics*; D011247:Pregnancy