[Comparative analysis of antimicrobial action of polyhexametylenguanide hydrochloride (Biopag) and chlorhexidine bigluconate upon potential infectious agent of suppurative-inflammatory diseases of maxillo-facial region and neck].
Sensitivity of microflora representatives isolated from inflammatory foci from 40 patients with suppurative-inflammatory diseases of maxillo-facial region and neck to different concentrations of antiseptic preparations of polyhexametylenguanide hydrochloride (Biopag) and chlorhexidine bigluconate was tested. It was determined that 0.05-0.1% solutions of these antiseptics were optimal for these diseases treatment. Biopag had more pronounced fungicidal action, less toxic and more prolonged antimicrobial action and better organoleptic properties when compared with chlorhexidine bigluconate.
Shipskiĭ
A V
AV
Afanas'ev
V V
VV
Polikarpov
N A
NA
Efimov
K M
KM
Dmitruk
I B
IB
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D000935:Antifungal Agents / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects / Q000302:isolation & purification; D001424:Bacterial Infections / Q000382:microbiology*; D002710:Chlorhexidine / Q000031:analogs & derivatives* / Q000494:pharmacology; D006146:Guanidines / Q000494:pharmacology*; D006801:Humans; D008826:Microbial Sensitivity Tests; D003904:Mitosporic Fungi / Q000187:drug effects / Q000302:isolation & purification; D009181:Mycoses / Q000382:microbiology*; D009057:Stomatognathic Diseases / Q000382:microbiology*; D013492:Suppuration / Q000382:microbiology
D000900:Anti-Bacterial Agents; D000935:Antifungal Agents; D006146:Guanidines; C060540:polyhexamethyleneguanidine; C010882:chlorhexidine gluconate; D002710:Chlorhexidine