Tubular adenoma with high-grade dysplasia in the ileal segment 34 years after augmentation ileocystoplasty: report of a first case.
Neoplasms of the urinary bladder following augmentation ileocystoplasty are rare. We present the case of a 39-year-old male with a tubular adenoma with high-grade dysplasia in the ileal segment 34 years after augmentation ileocystoplasty to enlarge a post-chemoradiation-induced shrunken bladder. He presented with gross hematuria. Cystoscopy revealed a papillary tumor at the site of ileovesical anastomosis, and transurethral resection was performed. Histologic examination revealed a tubular adenoma with high-grade dysplasia. There are only two previous reports of tubulovillous adenoma in ileal segment after ileocystoplasty, both without high-grade dysplasia. Our observation supports the hypothesis that an ileal neobladder may undergo all the morphologic and molecular changes observed in the development of gastrointestinal adenocarcinoma. Therefore, patients who had an ileal neobladder created should be closely followed.
Armah
Henry B
HB
Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA. armahh2@upmc.edu
Krasinskas
Alyssa M
AM
Parwani
Anil V
AV
J Urol. 2002 Jan;167(1):84-8
11743281
BJU Int. 2001 Aug;88(3):187-91
11488727
Scand J Urol Nephrol. 2003;37(3):202-4
12775277
Int J Urol. 2003 Sep;10(9):495-7
12941129
J Clin Pathol. 1992 Oct;45(10):928-9
1430267
World J Urol. 2004 Sep;22(3):227-34
15316739
J Urol. 1992 Apr;147(4):1013-6
1552576
Int J Urol. 2006 Aug;13(8):1134-5
16903947
Urology. 2006 Dec;68(6):1343.e9-10
17141834
J Urol. 1991 Sep;146(3):862-6
1714971
Urol Int. 1991;46(1):22-6
2024366
J Urol. 1990 Apr;143(4):671-8
2179579
J Urol. 1990 Sep;144(3):607-10
2201791
J Urol. 1990 Nov;144(5):1110-4
2231881
Br J Urol. 1989 Nov;64(5):489-92
2611620
J Urol. 1989 Jan;141(1):178-81
2908946
Urol Clin North Am. 1986 May;13(2):201-5
3515722
J Urol. 1984 Dec;132(6):1108-11
6502797
Science. 1980 Mar 7;207(4435):1079-80
7355272
Urol Res. 1995;23(1):21-5
7618231
J Urol. 1997 Feb;157(2):482-5; discussion 485-6
8996339
Urol Clin North Am. 1997 Nov;24(4):723-8
9391525
Br J Urol. 1998 Jan;81(1):55-61
9467477
J Urol. 1998 Aug;160(2):490-1
9679906
Eur Urol. 1999 Feb;35(2):98-101
9933802
Eur Urol. 1999 Dec;36(6):588-94
10559613
Dis Colon Rectum. 1999 Dec;42(12):1632-8
10613486
Urology. 1999 Sep;54(3):561
10754137
Urol Int. 2000;64(1):31-2
10782030
Cochrane Database Syst Rev. 2003;(1):CD003306
12535469