Acute physiologic predictors of mortality and functional and cognitive recovery in hemorrhagic stroke: 1-, 3-, and 6-month assessments.
This study was conducted to evaluate the prognostic values of acute physiologic parameters of mortality and functional and cognitive recovery. We studied 108 patients with hemorrhagic stroke admitted within 24 hours after stroke onset to a neurologic intensive care department. Details concerning potential physiologic predictors were collected (i.e., systolic and diastolic blood pressure, pulse rate, respiration rate, body temperature, hematocrit, Pao(2), Paco(2) and serum osmolality, pH, cholesterol, and glucose levels) at admission. As outcome variables, mortality and functional and cognitive recovery at 1, 3, and 6 months were measured. Results showed that blood pressure, serum pH, and Pao(2) on admission are significant predictors of mortality; that respiratory rate and hematocrit on admission are significant predictors of functional recovery; and that respiratory rate, Pao(2), and heart rate on admission predict cognitive recovery. It appears that the physiologic predictors of hemorrhagic stroke are remarkably dependent on outcome definitions (i.e., mortality, functional disability, or cognitive ability), but not with recovery times.
Seo
WhaSook
W
Department of Nursing, College of Medicine, Inha University, Incheon, Republic of Korea. wschang@inha.ac.kr <wschang@inha.ac.kr>
Oh
HyunSoo
H
D000208:Acute Disease; D000328:Adult; D000368:Aged; D017542:Aneurysm, Ruptured / Q000150:complications; D001786:Blood Glucose / Q000032:analysis; D001794:Blood Pressure; D001831:Body Temperature; D001925:Brain Damage, Chronic / Q000453:epidemiology / Q000209:etiology; D002245:Carbon Dioxide / Q000097:blood; D002543:Cerebral Hemorrhage / Q000097:blood / Q000401:mortality / Q000503:physiopathology* / Q000523:psychology; D002784:Cholesterol / Q000097:blood; D003072:Cognition Disorders / Q000453:epidemiology / Q000209:etiology; D048909:Diabetes Complications; D018450:Disease Progression; D005260:Female; D005500:Follow-Up Studies; D006339:Heart Rate; D006400:Hematocrit; D006801:Humans; D006863:Hydrogen-Ion Concentration; D006973:Hypertension / Q000150:complications; D002532:Intracranial Aneurysm / Q000150:complications; D008297:Male; D008875:Middle Aged; D009994:Osmolar Concentration; D017063:Outcome Assessment, Health Care; D010100:Oxygen / Q000097:blood; D010313:Partial Pressure; D011237:Predictive Value of Tests; D011379:Prognosis; D011446:Prospective Studies; D020127:Recovery of Function; D012119:Respiration; D012422:Rupture, Spontaneous; D013345:Subarachnoid Hemorrhage / Q000097:blood / Q000209:etiology / Q000401:mortality / Q000503:physiopathology / Q000523:psychology; D016019:Survival Analysis
D001786:Blood Glucose; D002245:Carbon Dioxide; D002784:Cholesterol; D010100:Oxygen