Successful outcome of human metapneumovirus (hMPV) pneumonia in a lung transplant recipient treated with intravenous ribavirin.
Human metapneumovirus (hMPV) has recently been shown to be a prominent cause of respiratory infections in immunocompromised hosts, and is associated with high morbidity and mortality. We report a case of hMPV pneumonia in a lung transplant recipient presenting with respiratory failure and sepsis syndrome. hMPV was diagnosed by polymerase chain reaction, and treated with intravenous ribavirin with a successful outcome.
Raza
Kashif
K
Division of Infectious Diseases, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA.
Ismailjee
Sameer B
SB
Crespo
Maria
M
Studer
Sean M
SM
Sanghavi
Sonali
S
Paterson
David L
DL
Kwak
Eun J
EJ
Rinaldo
Charles R
CR
Pilewski
Joseph M
JM
McCurry
Kenneth R
KR
Husain
Shahid
S
D000998:Antiviral Agents / Q000008:administration & dosage*; D001706:Biopsy; D001999:Bronchoscopy; D004279:DNA, Viral / Q000032:analysis; D003937:Diagnosis, Differential; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008168:Lung / Q000473:pathology / Q000821:virology; D016040:Lung Transplantation; D029121:Metapneumovirus / Q000235:genetics / Q000302:isolation & purification*; D008875:Middle Aged; D018184:Paramyxoviridae Infections / Q000175:diagnosis / Q000188:drug therapy* / Q000821:virology; D011024:Pneumonia, Viral / Q000175:diagnosis / Q000188:drug therapy* / Q000821:virology; D011183:Postoperative Complications; D029424:Pulmonary Disease, Chronic Obstructive / Q000601:surgery; D012254:Ribavirin / Q000008:administration & dosage*
D000998:Antiviral Agents; D004279:DNA, Viral; D012254:Ribavirin
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