title: The effect of lateral position on oxygenation in ARDS patients: a pilot study.
abstract: BACKGROUND
  The effect of body position on oxygenation in acute respiratory distress syndrome (ARDS) patients has long been known. Prone position improves the PaO2 in 60-70% of ARDS patients. However the effect of the lateral positions, which are used in routine critical care, has never been reported.
  
  
  OBJECTIVE
  To determine whether placing the patient in a lateral position has any effect on oxygenation in ARDS.
  
  
  METHODS
  Prospective observational study, comparing oxygenation in ARDS patients between supine, right and left lateral positions (> or = 60 degree).
  
  
  RESULTS
  We included 18 ARDS patients, their mean aged was 52.2 +/- 19.6 years, 14 were men and the ICU mortality rate was 61.1%. There was no significant change in the mean PaO2, arterial blood gas parameters, respiratory mechanics and hemodynamic parameters between the supine and decubitus positions in the overall group. However there was a trend toward increasing the mean PaO2 during right lateral position compared with the supine position (90.3 +/- 29.0 vs 84.6 +/- 20.4, p = 0.23). Nine patients who responded to the right lateral position had significantly higher mean PaO2 during the right lateral position than in the supine position (107.8 +/- 29.0 vs 85.6 +/- 21.8, p < 0.0001). In this group, four patients had predominant left pulmonary infiltration and five patients had equally bilateral pulmonary infiltration on chest X-ray. Unfortunately, the PaO2 in three patients decreased more than 10 mmHg during right lateral decubitus.
  
  
  CONCLUSIONS
  The PaO2 increased while in the right lateral position in patients with predominant left pulmonary infiltration or bilateral infiltration. This effect may be due to the small sample size. A further large-sized randomized controlled study is needed.
authors: Critical Care Unit, Division of Critical Care, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand. surat_ty@yahoo.co.uk
authors: Surat
authors: S
authors: Tongyoo
authors: Warakarn
authors: W
authors: Vilaichone
authors: Ranistha
authors: R
authors: Ratanarat
authors: Chairat
authors: C
authors: Permpikul
mesh_terms: D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010865:Pilot Projects; D011187:Posture / Q000502:physiology*; D016684:Prone Position; D011446:Prospective Studies; D011659:Pulmonary Gas Exchange / Q000502:physiology*; D012128:Respiratory Distress Syndrome / Q000503:physiopathology* / Q000517:prevention & control; D015656:Respiratory Mechanics; D012307:Risk Factors; D016683:Supine Position