title: Emotion regulation and potentiated startle across affective picture and threat-of-shock paradigms.
abstract: Past studies beginning with Jackson et al. [Jackson, D.C., Malmstadt, J.R., Larson, C.L., Davidson, R.J., 2000. Suppression and enhancement of emotional responses to unpleasant pictures. Psychophysiology 37 (4), 515-522.] document increases and decreases in emotionally-potentiated startle by way of instructing participants to enhance or suppress their emotional responses to symbolic sources of threat (unpleasant pictures). The present study extends this line of work to a threat-of-shock paradigm to assess whether startle potentiation elicited by threat of actual danger or pain is subject to emotion regulation. Results point to successful volitional modulation for both Affective-Picture and Threat-of-Shock experiments with startle magnitudes from largest to smallest occurring in the enhance, maintain, and suppress conditions. Successful regulation of startle potentiation to the threat of shock found by the current study supports the external validity of the Jackson paradigm for assessment of regulation processes akin to those occurring in the day-to-day context in response to real elicitors of emotion.
authors: Mood and Anxiety Disorders Program, National Institute of Mental Health, NIH, DHHS, 15K North Drive, Bethesda, MD 20892-2670, USA. lisseks@intra.nimh.nih.gov
authors: Shmuel
authors: S
authors: Lissek
authors: Kaebah
authors: K
authors: Orme
authors: Dana J
authors: DJ
authors: McDowell
authors: Linda L
authors: LL
authors: Johnson
authors: David A
authors: DA
authors: Luckenbaugh
authors: Johanna M
authors: JM
authors: Baas
authors: Brian R
authors: BR
authors: Cornwell
authors: Christian
authors: C
authors: Grillon
mesh_terms: D000223:Adaptation, Psychological; D000328:Adult; D000339:Affect; D001767:Blinking; D004576:Electromyography; D004597:Electroshock; D004644:Emotions; D005239:Fear; D005260:Female; D006801:Humans; D008297:Male; D009042:Motivation; D010364:Pattern Recognition, Visual; D013216:Reflex, Startle; D013561:Symbolism
references: J Abnorm Psychol. 1999 Feb;108(1):134-42
references: 10066999
references: Behav Neurosci. 2005 Aug;119(4):1118-24
references: 16187839
references: Psychol Rev. 2001 Jul;108(3):483-522
references: 11488376
references: Int J Psychophysiol. 1998 May;28(3):223-31
references: 9545658
references: Biol Psychiatry. 2006 Oct 1;60(7):760-6
references: 16631127
references: Behav Res Ther. 1998 Nov;36(11):1063-73
references: 9737058
references: Neuroimage. 2004 Oct;23(2):483-99
references: 15488398
references: Behav Neurosci. 1998 Oct;112(5):1069-79
references: 9829785
references: Clin J Pain. 2005 Sep-Oct;21(5):439-45
references: 16093750
references: J Psychopharmacol. 2005 Jul;19(4):347-56
references: 15982989
references: J Neurosci. 1982 Jun;2(6):791-805
references: 7086484
references: J Cogn Neurosci. 2002 Nov 15;14(8):1215-29
references: 12495527
references: Psychophysiology. 1990 Sep;27(5):513-22
references: 2274614
references: J Trauma Stress. 2003 Oct;16(5):471-9
references: 14584631
references: Clin Neurophysiol. 2003 Sep;114(9):1557-79
references: 12948786
references: Emotion. 2001 Sep;1(3):276-98
references: 12934687
references: Psychon Bull Rev. 1994 Dec;1(4):429-38
references: 24203551
references: Psychophysiology. 1991 Sep;28(5):588-95
references: 1758934
references: Psychol Rev. 1970 Sep;77(5):419-50
references: 4319167
references: J Abnorm Psychol. 1988 Nov;97(4):487-91
references: 3204235
references: J Abnorm Psychol. 2006 Feb;115(1):96-102
references: 16492100
references: Psychopharmacology (Berl). 2002 May;161(3):233-47
references: 12021826
references: J Cogn Neurosci. 2001 Aug 15;13(6):721-9
references: 11564317
references: Psychopharmacology (Berl). 2001 Oct;157(4):358-67
references: 11605094
references: J Abnorm Psychol. 1989 Nov;98(4):381-94
references: 2592672
references: J Psychopharmacol. 2005 May;19(3):249-58
references: 15888510
references: Psychol Sci. 2005 Jun;16(6):468-73
references: 15943673
references: Behav Brain Res. 1993 Dec 20;58(1-2):175-98
references: 8136044
references: Behav Res Ther. 1997 May;35(5):415-22
references: 9149450
references: Psychophysiology. 2000 Jul;37(4):515-22
references: 10934910
references: Biol Psychiatry. 1998 Nov 15;44(10):1027-36
references: 9821567
references: J Psychopharmacol. 1999;13(3):226-34
references: 10512076