title: Alpha-fetoprotein-producing pancreatic acinar cell carcinoma.
abstract: A 47-year-old man with chronic hepatitis B had progressive elevated alpha-fetoprotein of 2 years' duration. A pancreatic tail tumor, instead of liver tumor, was detected. He underwent elective distal pancreatectomy and splenectomy and the pathology turned out to be acinar cell carcinoma of the pancreas. Serum level of alpha-fetoprotein returned to normal soon after surgery. No cancer recurrence was noted after 3 years of follow-up. Alpha-fetoprotein is commonly used as a tumor marker to screen for hepatocellular carcinoma in high-risk patients. However, elevated alpha-fetoprotein could occur in a much rarer disease, acinar cell carcinoma of the pancreas.
authors: Department of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan.
authors: Yang-Chao
authors: YC
authors: Lin
authors: Po-Huang
authors: PH
authors: Lee
authors: Yu-Tung
authors: YT
authors: Yao
authors: Jong-Kai
authors: JK
authors: Hsiao
authors: Jin-Chuan
authors: JC
authors: Sheu
authors: Chien-Hung
authors: CH
authors: Chen
mesh_terms: D018267:Carcinoma, Acinar Cell / Q000378:metabolism*; D019694:Hepatitis B, Chronic / Q000150:complications; D006801:Humans; D008297:Male; D008875:Middle Aged; D010190:Pancreatic Neoplasms / Q000378:metabolism*; D000509:alpha-Fetoproteins / Q000096:biosynthesis*
chemical_list: D000509:alpha-Fetoproteins