Amping up estrogen receptors in breast cancer.
This article highlights a recent study by Holst et al. in Nature Genetics that finds estrogen receptor-alpha (ER-alpha) amplification in early benign lesions and more advanced invasive carcinomas of the breast, and discusses the potential implications to our present understanding of the role of ER-alpha in breast tumorigenesis.
Fowler
Amy M
AM
Department of Oncology, University of Wisconsin-Madison, Madison, WI 53706, USA.
Alarid
Elaine T
ET
D001943:Breast Neoplasms / Q000378:metabolism*; D047628:Estrogen Receptor alpha / Q000502:physiology*; D005260:Female; D006801:Humans
D047628:Estrogen Receptor alpha
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