Antibiotic susceptibility of blood culture isolates of anaerobic bacteria at a Norwegian university hospital.
In the present study the susceptibility of 200 blood culture isolates of anaerobic bacteria to benzylpenicillin, clindamycin, metronidazole, imipenem and piperacillin-tazobactam was examined. Metronidazole, imipenem, and piperacillin-tazobactam showed the highest activity, with 98.5% of the isolates being fully susceptible to either agent. A high rate of reduced susceptibility to clindamycin among both Bacteroides spp. (37%) and Clostridium spp. (28%) was found. Almost all Bacteroides isolates were resistant to penicillin, and only 60% of Prevotella spp. were susceptible to this agent. The antibiotic susceptibility of anaerobic bacteria in Norway should be surveyed regularly.
Kommedal
Oyvind
O
Department of Microbiology and Immunology, The Gade Institute, Haukeland University Hospital, Bergen, Norway. oeyvind.kommedal@helse-bergen.no
Nystad
Tone Wikene
TW
Bølstad
Bente
B
Digranes
Asbjørn
A
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D016470:Bacteremia / Q000382:microbiology*; D001421:Bacteria, Anaerobic / Q000187:drug effects*; D002981:Clindamycin / Q000494:pharmacology; D006785:Hospitals, University; D006801:Humans; D008826:Microbial Sensitivity Tests
D000900:Anti-Bacterial Agents; D002981:Clindamycin