title: Two new coumarin glucosides from the roots of Angelica apaensis and their anti-platelet aggregation activity.
abstract: Two new coumarin glucosides, 11-O-beta-D-glucopyranosyl thamnosmonin (1) and 12-O-beta-D-glucopyranosyl gosferol (2), were isolated from the roots of Angelica apaensis. Their structures were elucidated spectroscopically. Both compounds showed weak inhibitory effects on rabbit platelet aggregation induced by PAF, AA and APD.
authors: State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, Yunnan, China.
authors: Wei-Lie
authors: WL
authors: Xiao
authors: Sheng-Hong
authors: SH
authors: Li
authors: Yun-Heng
authors: YH
authors: Shen
authors: Xue-Mei
authors: XM
authors: Niu
authors: Han-Dong
authors: HD
authors: Sun
mesh_terms: D029969:Angelica / Q000737:chemistry*; D000818:Animals; D003374:Coumarins / Q000302:isolation & purification* / Q000494:pharmacology; D005960:Glucosides / Q000302:isolation & purification* / Q000494:pharmacology; D066298:In Vitro Techniques; D018517:Plant Roots / Q000737:chemistry; D010974:Platelet Aggregation / Q000187:drug effects; D010975:Platelet Aggregation Inhibitors / Q000302:isolation & purification* / Q000494:pharmacology; D011817:Rabbits
chemical_list: C523372:11-O-glucopyranosyl thamnosmonin; C523373:12-O-glucopyranosyl gosferol; D003374:Coumarins; D005960:Glucosides; D010975:Platelet Aggregation Inhibitors