title: Occupationally related outbreak of chickenpox in an intensive care unit.
abstract: OBJECTIVE
  To report occupationally related outbreak of chickenpox in intensive care unit (ICU).
  
  
  METHODS
  The index patient was a 4-year-old child who presented with a 3-day history of fever and rash and was clinically diagnosed as chickenpox encephalitis. She was admitted to an isolation room in ICU, kept on oxygen mask and given intravenous fluids, anticonvulsant, antipyretic and acyclovir. Twelve hours later, the patient was transferred to Infectious Diseases Hospital. Secondary cases were three unvaccinated ICU staff nurses who developed chickenpox 16-21 days following exposure. They were also transferred to Infectious Diseases Hospital. The affected nurses were interviewed and filled out a questionnaire. Individual immune status was verified by reviewing previous varicella zoster-IgG screening data for all ICU staff. The chickenpox case was defined according to the CDC case classification. All were treated with no complications.
  
  
  CONCLUSIONS
  This report shows that adherence to isolation precautions, exclusion of susceptible staff from attending the affected patient, education, pre-employment anti-VZV-IgG screening and vaccine coverage of staff could have prevented the occurrence of this outbreak.
authors: Department of Tropical Medicine and Hygiene, Faculty of Medicine, University of Alexandria, Alexandria, Egypt. nasseryehia@gmail.com
authors: Nasser Yehia A
authors: NY
authors: Aly
authors: Ina'am
authors: I
authors: Al Obaid
authors: Noura
authors: N
authors: Al-Qulooshi
authors: Zahida
authors: Z
authors: Zahed
mesh_terms: D000328:Adult; D002644:Chickenpox / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy / Q000635:transmission*; D002675:Child, Preschool; D004196:Disease Outbreaks / Q000517:prevention & control*; D005260:Female; D006801:Humans; D017758:Infectious Disease Transmission, Patient-to-Professional / Q000517:prevention & control*; D007362:Intensive Care Units; D009741:Nursing Staff, Hospital; D009784:Occupational Diseases / Q000175:diagnosis / Q000453:epidemiology* / Q000628:therapy