title: Porous bioceramics reinforced by coating gelatin.
abstract: Porous bioceramics with high porosity for bone tissue engineering were fabricated by the foam impregnation technique, but their mechanical strength was poor, only a mean compressive strength of 1.04+/-0.15 MPa and an mean elastic modulus of 0.1 GPa. In order to reinforce porous ceramics, the ceramic samples were immersed in 5% gelatin solution and gelatin coatings were formed on the inter-surface of their pores. It was found that the mean compressive strength value and the mean elastic modulus value of porous samples coated with gelatin were improved to 5.17+/-0.17 MPa and 0.3 GPa respectively without sacrificing their porosity greatly. Moreover composite samples were not as fragile as sintered ceramics. The results indicated that the gelatin coatings on the inter-surface of pores reinforced porous bioceramics effectively.
authors: School of Materials Science and Engineering, Southeast University, Jiangning District, Nanjing, 211189, China.
authors: Bin
authors: B
authors: Liu
authors: Pinghua
authors: P
authors: Lin
authors: Yan
authors: Y
authors: Shen
authors: Yinsheng
authors: Y
authors: Dong
mesh_terms: D002516:Ceramics / Q000138:chemical synthesis* / Q000737:chemistry; D020099:Coated Materials, Biocompatible / Q000737:chemistry*; D019245:Compressive Strength; D004548:Elasticity; D005780:Gelatin / Q000737:chemistry* / Q000494:pharmacology; D008422:Materials Testing; D016062:Porosity; D013499:Surface Properties
chemical_list: D020099:Coated Materials, Biocompatible; D005780:Gelatin
references: J Biomed Mater Res. 2000 Sep 15;51(4):680-4
references: 10880116
references: Biomaterials. 1996 Jan;17(2):83-91
references: 8624400
references: J Mater Sci Mater Med. 1999 Mar;10(3):135-45
references: 15348161
references: J Biomed Mater Res A. 2005 Dec 15;75(4):832-40
references: 16138342
references: Biomaterials. 2002 Aug;23(15):3063-72
references: 12102177
references: J Biomed Mater Res A. 2005 Feb 1;72(2):136-45
references: 15549783
references: Biomaterials. 2004 Sep;25(21):5171-80
references: 15109841
references: Biomaterials. 2004 Jun;25(14):2893-9
references: 14962568
references: Biomaterials. 2004 Aug;25(17):3671-80
references: 15020142
references: J Mater Sci Mater Med. 2003 Mar;14(3):201-9
references: 15348465
references: J Biomed Mater Res. 2001 Mar 15;54(4):525-30
references: 11426597
references: J Biomed Mater Res A. 2006 Jan;76(1):196-205
references: 16265636