Serological evidence of possible human infection with Tioman virus, a newly described paramyxovirus of bat origin.
Tioman virus, a relatively new paramyxovirus, was isolated from fruit bats (Pteropus species) on Tioman Island, Malaysia, in 2001. The objective of this study was to determine the prevalence of antibodies to T. virus in island inhabitants, by use of comparative ELISA and serum neutralization assays. Of the 169 human sera analyzed, 5 (approximately 3.0%) were positive for T. virus, by comparative ELISA. Of these 5 sera, 3 (1.8% of the total) had neutralizing antibodies against T. virus, suggesting previous infection of this study population by this virus or a similar virus.
Yaiw
Koon Chu
KC
Department of Pathology, University of Malaya, Kuala Lumpur, Malaysia.
Crameri
Gary
G
Wang
Linfa
L
Chong
Heng Thay
HT
Chua
Kaw Bing
KB
Tan
Chong Tin
CT
Goh
Khean Jin
KJ
Shamala
Devi
D
Wong
K Thong
KT
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000818:Animals; D000914:Antibodies, Viral / Q000097:blood*; D002685:Chiroptera / Q000821:virology*; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D008296:Malaysia / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D009500:Neutralization Tests; D018184:Paramyxoviridae Infections / Q000453:epidemiology* / Q000276:immunology / Q000635:transmission / Q000662:veterinary; D018098:Paramyxovirinae / Q000276:immunology*; D016036:Seroepidemiologic Studies; D015047:Zoonoses
D000914:Antibodies, Viral