title: Enzymatic synthesis of aromatic polyketides using PKS4 from Gibberella fujikuroi.
authors: Department of Chemical and Biomolecular Engineering, University of California, Los Angeles, California 90095, USA.
authors: Suzanne M
authors: SM
authors: Ma
authors: Jixun
authors: J
authors: Zhan
authors: Kenji
authors: K
authors: Watanabe
authors: Xinkai
authors: X
authors: Xie
authors: Wenjun
authors: W
authors: Zhang
authors: Clay C
authors: CC
authors: Wang
authors: Yi
authors: Y
authors: Tang
mesh_terms: D003500:Cyclization; D005874:Gibberella / Q000201:enzymology*; D018942:Macrolides / Q000138:chemical synthesis* / Q000378:metabolism; D008316:Malonyl Coenzyme A / Q000737:chemistry / Q000378:metabolism; D048630:Polyketide Synthases / Q000737:chemistry* / Q000302:isolation & purification / Q000378:metabolism; D017434:Protein Structure, Tertiary; D044004:Xanthones / Q000737:chemistry / Q000378:metabolism
chemical_list: D018942:Macrolides; D044004:Xanthones; C000269:bikaverin; D008316:Malonyl Coenzyme A; D048630:Polyketide Synthases
references: Eur J Biochem. 1998 Oct 15;257(2):395-402
references: 9826185
references: J Mol Biol. 2002 Oct 25;323(3):585-98
references: 12381311
references: J Biotechnol. 2006 Aug 5;124(4):690-703
references: 16716432
references: Nat Prod Rep. 2007 Apr;24(2):393-416
references: 17390002
references: J Nat Prod. 2007 Feb;70(2):227-32
references: 17286429
references: Chem Biol. 2001 Feb;8(2):189-97
references: 11251292
references: PLoS Biol. 2004 Feb;2(2):E31
references: 14966533
references: Org Biomol Chem. 2007 Jul 7;5(13):2010-26
references: 17581644
references: Fungal Genet Biol. 2002 Nov;37(2):134-48
references: 12409099
references: Chembiochem. 2001 Sep 3;2(9):612-27
references: 11828498
references: J Am Chem Soc. 2007 Jan 10;129(1):36-7
references: 17199276
references: Biochemistry. 2000 Aug 1;39(30):8853-8
references: 10913297
references: Biochemistry. 2003 Jun 3;42(21):6588-95
references: 12767243
references: Proc Natl Acad Sci U S A. 2006 Nov 7;103(45):16728-33
references: 17071746