title: Hydroxyl-directed nitrile oxide cycloaddition reactions with cyclic allylic alcohols.
abstract: Diastereoselective cycloaddition reactions between a nitrile oxide and cyclic allylic alcohols are reported. The products isolated are densely functionalized building blocks that are not otherwise easily accessed with existing methods and concepts previously established for the construction of acyclic polyketides.
authors: Laboratorium für Organische Chemie, ETH Zurich, CH-8093 Zürich, Switzerland.
authors: Nina
authors: N
authors: Becker
authors: Erick M
authors: EM
authors: Carreira
mesh_terms: D003500:Cyclization; D006859:Hydrogen / Q000737:chemistry*; D007536:Isomerism; D015394:Molecular Structure; D009573:Nitrites / Q000737:chemistry*; D010080:Oxazoles / Q000737:chemistry; D010087:Oxides / Q000138:chemical synthesis* / Q000737:chemistry; D020005:Propanols / Q000737:chemistry*
chemical_list: D009573:Nitrites; D010080:Oxazoles; D010087:Oxides; D020005:Propanols; C064210:oxazolidine; C006463:allyl alcohol; D006859:Hydrogen