Dysgerminoma in a child with ataxia-telangiectasia.
Ataxia-telangiectasia is an autosomal recessive disease characterized by progressive cerebellar ataxia, oculocutaneous telangiectasia, immunodeficiency, high incidence of cancer, and increased sensitivity to ionizing radiation. The authors report a case of dysgerminoma in a child with high alpha-fetoprotein, CA125 and beta-human chorionic gonadotropin, who has been followed-up for ataxia-telangiectasia for 2 years.
Koksal
Yavuz
Y
Selcuk University, Meram Faculty of Medicine, Department of Pediatric Oncology, Konya, Turkey. yavuzkoksal@yahoo.com
Caliskan
Umran
U
Ucar
Canan
C
Yurtcu
Muslim
M
Artac
Hasibe
H
Ilerisoy-Yakut
Zeynep
Z
Reisli
Ismail
I
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects / Q000627:therapeutic use; D001260:Ataxia Telangiectasia / Q000097:blood / Q000150:complications* / Q000628:therapy; D014408:Biomarkers, Tumor / Q000097:blood; D001761:Bleomycin / Q000008:administration & dosage / Q000009:adverse effects; D018394:CA-125 Antigen / Q000097:blood; D016190:Carboplatin / Q000008:administration & dosage; D002648:Child; D018997:Chorionic Gonadotropin, beta Subunit, Human / Q000097:blood; D004407:Dysgerminoma / Q000188:drug therapy / Q000209:etiology* / Q000601:surgery; D005047:Etoposide / Q000008:administration & dosage; D005260:Female; D005500:Follow-Up Studies; D020022:Genetic Predisposition to Disease; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use; D009363:Neoplasm Proteins / Q000097:blood; D010051:Ovarian Neoplasms / Q000188:drug therapy / Q000209:etiology* / Q000601:surgery; D010052:Ovariectomy; D012120:Respiration Disorders / Q000139:chemically induced; D000509:alpha-Fetoproteins / Q000032:analysis
D014408:Biomarkers, Tumor; D018394:CA-125 Antigen; D018997:Chorionic Gonadotropin, beta Subunit, Human; D016756:Immunoglobulins, Intravenous; D009363:Neoplasm Proteins; D000509:alpha-Fetoproteins; D001761:Bleomycin; D005047:Etoposide; D016190:Carboplatin