title: [Prevention of prion disease transmission].
abstract: Prion infections lead to fatal diseases of the CNS, including Creutzfeldt-Jakob disease (CJD) in humans, bovine spongiform encephalopathy(BSE) in cows. Iatrogenic CJD which have been transmitted through dura-matter transplantation, administration of pituitary tissue extracts, corneal transplantation, or neurosurgical procedures. There are not thought to be infectious agents in blood of sporadic CJD patients. However three recipients of blood donated by individuals who subsequently developed variant CJD in United Kingdam. We introduce the guideline for CJD infection through medical procedure made in 2003 and arouse attention to risk of blood in variant CJD patients.
authors: Department of Neurology, Yokohama City University.
authors: Hitaru
authors: H
authors: Kishida
authors: Yoshiyuki
authors: Y
authors: Kuroiwa
mesh_terms: D000818:Animals; D001803:Blood Transfusion; D002417:Cattle; D016039:Corneal Transplantation / Q000009:adverse effects; D007562:Creutzfeldt-Jakob Syndrome / Q000209:etiology / Q000517:prevention & control* / Q000635:transmission*; D004388:Dura Mater / Q000637:transplantation; D006801:Humans; D007049:Iatrogenic Disease; D019635:Neurosurgical Procedures / Q000009:adverse effects; D010902:Pituitary Gland; D017410:Practice Guidelines as Topic; D013242:Sterilization; D013525:Surgical Instruments; D014020:Tissue Extracts / Q000009:adverse effects
chemical_list: D014020:Tissue Extracts