[A case of corticosteroid allergy].
A 42-year old female patient developed a corticosteroid-induced allergic contact dermatitis. She had severe atopic dermatitis and had received treatment with steroid-containing ointments over a period of decades. After an intra-articular injection with steroids (Predni H-injekt 10((R)), Prednisolone acetate) she developed severe erythema and edema in and around the area of the injection. The allergological assessment revealed a type-IV-sensitivity to group D2-corticosteroids (No methyl substitution on C(16), side chain ester on C(17), possibly a side chain on C(21); according to the latest classification). The occurrence of contact allergy to corticosteroids in Germany ranges between 1.1% and 3.1%.
Gall
H M
HM
Hautklinik am Klinikum Nürnberg Nord, Akademisches Lehrkrankenhaus der Universität Erlangen-Nürnberg.
Paul
E
E
D000305:Adrenal Cortex Hormones / Q000009:adverse effects*; D000328:Adult; D017449:Dermatitis, Allergic Contact / Q000175:diagnosis* / Q000209:etiology* / Q000517:prevention & control; D005260:Female; D006801:Humans; D011239:Prednisolone / Q000009:adverse effects*
D000305:Adrenal Cortex Hormones; D011239:Prednisolone