title: Cell tracking using magnetic resonance imaging.
abstract: Cell tracking by in vivo magnetic resonance imaging (MRI) requires strategies of labelling the cells with MRI contrast agents. The principal routes to achieve efficient cell labelling for neurological applications are discussed with methodological advantages and caveats. Beyond temporo-spatial localization of labelled cells, the investigation of functional cell status is of great interest to allow studies of functional cell dynamics. The two major approaches to reach this goal, use of responsive contrast agents and generation of transgenic cell lines, are discussed.
authors: In-vivo-NMR Laboratory, Max-Planck-Institute for Neurological Research, Gleueler Strasse 50, D-50931 Köln, Germany. mathias@nf.mpg.de
authors: Mathias
authors: M
authors: Hoehn
authors: Dirk
authors: D
authors: Wiedermann
authors: Carles
authors: C
authors: Justicia
authors: Pedro
authors: P
authors: Ramos-Cabrer
authors: Klaus
authors: K
authors: Kruttwig
authors: Tracy
authors: T
authors: Farr
authors: Uwe
authors: U
authors: Himmelreich
mesh_terms: D000818:Animals; D002468:Cell Physiological Phenomena; D003287:Contrast Media; D005290:Ferric Compounds; D008264:Macrophages / Q000502:physiology; D008279:Magnetic Resonance Imaging; D053768:Metal Nanoparticles; D009474:Neurons / Q000502:physiology; D013194:Staining and Labeling / Q000379:methods*; D020521:Stroke / Q000276:immunology
chemical_list: D003287:Contrast Media; D005290:Ferric Compounds; C000499:ferric oxide
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