[Pelargonium sidoides-extract (EPs 7630): registration confirms efficacy and safety].
For centuries the roots of Pelargonium sidoides DC have been used in South African ethno-medicine for the treatment of respiratory diseases. In Germany, a medicinal product containing a special extract of this substance is among the group of self-medication products most widely bought at chemist's shops. In December 2005, the Federal Institute for Drugs and Medical Devices (BfArM, Bonn) approved a new license for its use as a drug. The following review focuses on the current pharmacological, toxicological and clinical data covering the efficacy and innocuousness of this drug when administered for the treatment of acute bronchitis.
Conrad
Andreas
A
Institut für Umweltmedizin und Krankenhaushygiene, Universitätsklinikum Freiburg, Freiburg, Germany.
Kolodziej
Herbert
H
Schulz
Volker
V
D000208:Acute Disease; D000328:Adult; D001991:Bronchitis / Q000175:diagnosis / Q000188:drug therapy*; D002648:Child; D002675:Child, Preschool; D018849:Controlled Clinical Trials as Topic; D017277:Drug Approval; D005260:Female; D005858:Germany; D006801:Humans; D008297:Male; D031316:Pelargonium; D008517:Phytotherapy; D010936:Plant Extracts / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D012449:Safety; D013997:Time Factors; D016896:Treatment Outcome
C476332:EPs 7630; D010936:Plant Extracts
Phytomedicine. 2003;10 Suppl 4:18-24
12807338
Curr Med Res Opin. 2007 Feb;23(2):323-31
17288687
Phytomedicine. 2007;14 Suppl 6:52-9
17182236
Phytomedicine. 2007;14 Suppl 6:46-51
17184983
Phytother Res. 2001 Mar;15(2):122-6
11268110
Phytomedicine. 2007;14 Suppl 6:60-4
17184982
Explore (NY). 2005 Nov;1(6):437-45
16781588
Phytomedicine. 2007;14 Suppl 6:40-5
17188479
Phytomedicine. 2007;14 Suppl 6:32-9
17218089
Phytomedicine. 2007;14 Suppl 6:18-26
17188480
Phytomedicine. 2007;14 Suppl 6:65-8
17184984
Phytomedicine. 2005 Jan;12(1-2):46-51
15693707
Phytomedicine. 2006 Sep;13(8):570-5
16920512
Phytomedicine. 2007;14 Suppl 6:9-17
17188477
Phytomedicine. 2007;14 Suppl 6:27-31
17182237
Phytomedicine. 2007;14 Suppl 6:69-73
17184981
Bioorg Med Chem. 2005 Dec 1;13(23):6470-6
16143535
Am J Med. 1999 Jul;107(1):62-7
10403354