Chemical Constituents from the Stems of Morinda citrifolia Linn.
Studies on the chemical constituents of the stems of Morinda citrifolia, Linn. have led to the isolation of two new compounds, morindicone (9-hydroxy-2-methoxy-4-methyl-3,10-anthracenedione, 1) and morinthone (4-methoxy-3-heptadecylxanthone, 2), as well as two known constituents, 1-hydroxy-2-methylanthraquinone (3) and 2-hydroxymethylanthraquinone (4). Their structures were elucidated by spectral analysis including 2D NMR techniques.
Siddiqui
Bina S
BS
International Center for Chemical Sciences, H.E.J. Research Institute of Chemistry, and Dr. Panjwani Center for Molecular Medicine and Drug Research, University of Karachi, Karachi-75270, Pakistan. bina@khi.comsats.net.pk
Sattar
Fouzia A
FA
Begum
Sabira
S
Gulzar
Tahsin
T
Ahmad
Fayaz
F
D000818:Animals; D000880:Anthraquinones / Q000302:isolation & purification* / Q000494:pharmacology / Q000627:therapeutic use; D000890:Anti-Infective Agents / Q000302:isolation & purification* / Q000494:pharmacology / Q000627:therapeutic use; D000959:Antihypertensive Agents / Q000008:administration & dosage / Q000302:isolation & purification* / Q000627:therapeutic use; D000975:Antioxidants / Q000302:isolation & purification* / Q000494:pharmacology / Q000627:therapeutic use; D006801:Humans; D015394:Molecular Structure; D032066:Morinda / Q000737:chemistry*; D019906:Nuclear Magnetic Resonance, Biomolecular; D018547:Plant Stems / Q000737:chemistry; D044004:Xanthones / Q000302:isolation & purification* / Q000494:pharmacology / Q000627:therapeutic use
D000880:Anthraquinones; D000890:Anti-Infective Agents; D000959:Antihypertensive Agents; D000975:Antioxidants; D044004:Xanthones; C523370:morindicone; C523371:morinthone