[Mesenchymal stem cells applied in therapy for acute radiation injury].
Mesenchymal stem cells are a kind of non-hematopoietic adult stem cells with selfrenewal and multilineage differentiation potential, which have special biological characteristics, such as secreting hematopoietic growth factors, reconstructing hematopoietic microenvironment, low immunogenicity, and can be transfected and expressed by exogenous gene. This article summarizes the biological characteristics of MSCs and their models of application to acute radiation disease in animals.
Li
Ming
M
Beijing Institute of Radiation Medicine, Beijing 100850, China.
Wang
Li-Sheng
LS
Luo
Qing-Liang
QL
D000208:Acute Disease; D000818:Animals; D004195:Disease Models, Animal; D006801:Humans; D045164:Mesenchymal Stem Cell Transplantation; D059630:Mesenchymal Stem Cells / Q000166:cytology* / Q000187:drug effects / Q000502:physiology; D011832:Radiation Injuries / Q000628:therapy*