title: [Superior mesenteric and portal vein thrombosis in a polycythemia vera patient with JAK2 mutation].
abstract: A 47-year-old woman was admitted to our hospital in December 1994 with polycythemia. The patient's red blood cell volume was 33 ml/kg and bone marrow cytology was able to rule out other myeloproliferative diseases such as chronic myelogenous leukemia, essential thrombocytosis and myelofibrosis. The patient was diagnosed as having polycythemia vera. She had undergone only phlebotomy until 1999 when the thrombocytosis appeared, subsequent to which she was treated with oral hydroxyurea. However, in March 2006, she developed upper abdominal pain and was admitted to our hospital on March 14th, 2006. Computed tomography scan revealed thromboses in the portal and superior mesenteric veins. Anticoagulation therapy delivered intravenously via the superior mesenteric vein dramatically improved her symptoms and liver function. She is currently on anticoagulation therapy in our outpatient clinic.
authors: Fourth Department of Internal Medicine, Sapporo Medical University School of Medicine.
authors: Naoko
authors: N
authors: Araki
authors: Rishu
authors: R
authors: Takimoto
authors: Hiroki
authors: H
authors: Chiba
authors: Hironobu
authors: H
authors: Araki
authors: Tsutomu
authors: T
authors: Sato
authors: Satoshi
authors: S
authors: Iyama
authors: Masahiro
authors: M
authors: Hirakawa
authors: Kaoru
authors: K
authors: Ono
authors: Yutaka
authors: Y
authors: Kawano
authors: Koichi
authors: K
authors: Takada
authors: Koji
authors: K
authors: Miyanishi
authors: Masayoshi
authors: M
authors: Kobune
authors: Takuya
authors: T
authors: Matsunaga
authors: Junji
authors: J
authors: Kato
authors: Tokiko
authors: T
authors: Nakamura
authors: Yoshiro
authors: Y
authors: Niitsu
mesh_terms: D005260:Female; D006801:Humans; D053614:Janus Kinase 2 / Q000235:genetics*; D008641:Mesenteric Vascular Occlusion / Q000209:etiology*; D008642:Mesenteric Veins; D008875:Middle Aged; D017354:Point Mutation; D011087:Polycythemia Vera / Q000150:complications* / Q000235:genetics; D011169:Portal Vein; D020246:Venous Thrombosis / Q000209:etiology*
chemical_list: D053614:Janus Kinase 2