title: Catamenial hemoptysis and pneumothorax in a patient with cystic fibrosis.
abstract: Hemoptysis or pneumothorax that recurs with the onset of menses is strongly suggestive of thoracic endometriosis syndrome (TES). TES is a rare disorder, with relatively few cases reported in the literature. A 32-year-old woman with cystic fibrosis, who over a period of several months had experienced recurrent catamenial hemoptysis and pneumothoraces, including an episode of life-threatening hemoptysis that coincided with menstruation, is presented. Thoracic computed tomography and magnetic resonance imaging scans, as well as a bronchoscopic evaluation that demonstrated endobronchial lesions that disappeared after menses, support the diagnosis of TES in the present patient. The patient was treated empirically with danazol and subsequently underwent a successful double-lung transplantation. Danazol was discontinued postoperatively, and she was started on an oral contraceptive. Eighteen months post-transplant, she has not experienced a recurrence of her catamenial symptoms, despite having resumed a regular menstrual cycle.
authors: Division of Respiratory and Critical Care Medicine, Department of Medicine, Queen's University, 102 Stuart Street, Kingston, Ontario, Canada. parkerc@post.queensu.ca
authors: Chris M
authors: CM
authors: Parker
authors: Robert
authors: R
authors: Nolan
authors: M Diane
authors: MD
authors: Lougheed
mesh_terms: D000328:Adult; D003550:Cystic Fibrosis / Q000150:complications*; D003613:Danazol / Q000627:therapeutic use; D004715:Endometriosis / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D004965:Estrogen Antagonists / Q000627:therapeutic use; D005260:Female; D006469:Hemoptysis / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D006801:Humans; D016040:Lung Transplantation / Q000379:methods; D008598:Menstruation; D011030:Pneumothorax / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D013577:Syndrome; D016896:Treatment Outcome
chemical_list: D004965:Estrogen Antagonists; D003613:Danazol
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