title: Assessment of T staging and mesorectal fascia status using high-resolution MRI in rectal cancer with rectal distention.
abstract: OBJECTIVE
  To determine the accuracy of high-resolution magnetic resonance imaging (MRI) using phased-array coil for preoperative assessment of T staging and mesorectal fascia infiltration in rectal cancer with rectal distention.
  
  
  METHODS
  In a prospective study of 67 patients with primary rectal cancer, high-resolution magnetic resonance imaging (in-plane resolution, 0.66 multiply 0.56) with phased-array coil were performed for T-staging and measurement of distance between the tumor and the mesorectal fascia. The assessment of MRI was compared with postoperative histopathologic findings. Sensitivity, specificity, accuracy, positive predictive value, and negative predictive value were evaluated.
  
  
  RESULTS
  The overall magnetic resonance accuracy was 85.1% for T staging and 88% for predicting mesorectal fascia involvement. Magnetic resonance sensitivity, specificity, accuracy, positive predictive value, and negative predictive value was 70%, 97.9%, 89.6%, 93.3% and 88.5% for <or= T2 tumors, 90.5%, 76%, 85.1%, 86.4% and 82.6% for T3 tumors, 100%, 95.2%, 95.5%, 62.5% and 100% for T4 tumors, and 80%, 90.4%, 88%, 70.6% and 94% for predicting mesorectal fascia involvement, respectively.
  
  
  CONCLUSIONS
  High-resolution MRI enables accurate preoperative assessment for T staging and mesorectal fascia infiltration in rectal cancer with rectal distention.
authors: Department of Radiology, Zhongshan Hospital, Shanghai Medical Imaging Institute, 180 Fenglin Rd, Shanghai 200032, China.
authors: Sheng-Xiang
authors: SX
authors: Rao
authors: Meng-Su
authors: MS
authors: Zeng
authors: Jian-Ming
authors: JM
authors: Xu
authors: Xin-Yu
authors: XY
authors: Qin
authors: Cai-Zhong
authors: CZ
authors: Chen
authors: Ren-Chen
authors: RC
authors: Li
authors: Ying-Yong
authors: YY
authors: Hou
mesh_terms: D005205:Fascia / Q000473:pathology*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D011300:Preoperative Care; D011446:Prospective Studies; D012004:Rectal Neoplasms / Q000473:pathology*; D012007:Rectum / Q000473:pathology*; D012680:Sensitivity and Specificity
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