Variation of crystal structure of hydroxyapatite in calcium phosphate cement by the substitution of strontium ions.
New routes were used to introduce strontium into calcium phosphate cement in the present article. The study showed that by mixing 50 wt% amorphous calcium phosphate + amorphous strontium phosphate and 50 wt% dicalcium phosphate dihydrate, hydroxyapatite and Sr-hydroxyapatite precipitated separately in the hydrated cement; whereas, by mixing 50 wt% Sr- amorphous calcium phosphate and 50 wt% dicalcium phosphate dihydrate, strontium can be doped into hydroxyapatite lattice and increase the lattice dimensions and lattice volume. The strontium substituted calcium phosphate cement has potential for use in orthopedic surgeries.
Wang
Xiupeng
X
Key Laboratory of Specially Functional Materials, South China University of Technology, Ministry of Education, Guangzhou 510641, China. xiupengw@163.com
Ye
Jiandong
J
D002130:Calcium Phosphates / Q000737:chemistry*; D003460:Crystallization; D017886:Durapatite / Q000737:chemistry*; D007477:Ions / Q000737:chemistry / Q000494:pharmacology; D019279:Resin Cements / Q000737:chemistry*; D013057:Spectrum Analysis; D013324:Strontium / Q000737:chemistry / Q000494:pharmacology*; D014961:X-Ray Diffraction
D002130:Calcium Phosphates; D007477:Ions; D019279:Resin Cements; D017886:Durapatite; C020243:calcium phosphate; D013324:Strontium
Biomaterials. 2005 Jul;26(19):4073-83
15664634
J Biomed Mater Res. 1991 Apr;25(4):485-98
2050712
Arch Otolaryngol Head Neck Surg. 1991 Apr;117(4):385-9
1848767
J Mater Sci Mater Med. 2005 Nov;16(11):993-1001
16388381
Eur J Nucl Med. 1986;12 (9):447-54
3102236
J Biomed Mater Res A. 2004 Mar 1;68(3):513-21
14762931
Dent Mater. 2003 Dec;19(8):797-804
14511739
J Mater Sci Mater Med. 1999 Mar;10(3):177-83
15348166