"Thyrotoxic psychosis" associated with subacute thyroiditis.
Severe psychiatric derangements are a rare manifestation of Graves disease or toxic goiter. An 18-year-old male college student was hospitalized with depression and psychotic behavior. He was found to have thyrotoxicosis due to subacute thyroiditis, as evidenced by a reduced radioactive iodine uptake, elevated thyroglobulin level, and spontaneous remission into a hypothyroid phase. His behavioral abnormalities resolved with progressive normalization of thyroid function. To our knowledge, this is the first reported case of the self-limited condition of subacute thyroiditis causing 'thyrotoxic psychosis' and serves to remind clinicians of this association when treating patients in clinical practice.
Rizvi
Ali A
AA
Division of Endocrinology, Diabetes, and Metabolism, University of South Carolina School of Medicine, Columbia, SC, USA. arizvi@gw.mp.sc.edu
D000293:Adolescent; D000928:Antidepressive Agents / Q000627:therapeutic use; D014150:Antipsychotic Agents / Q000627:therapeutic use; D006801:Humans; D008297:Male; D011618:Psychotic Disorders / Q000097:blood / Q000188:drug therapy / Q000209:etiology*; D013963:Thyroid Hormones / Q000097:blood*; D013968:Thyroiditis, Subacute / Q000097:blood / Q000150:complications* / Q000188:drug therapy; D016896:Treatment Outcome
D000928:Antidepressive Agents; D014150:Antipsychotic Agents; D013963:Thyroid Hormones