Comment on developmental toxicity evaluation on Vorinostat and relationship with HDAC inhibition.
Giavini
Erminio
E
D000014:Abnormalities, Drug-Induced / Q000201:enzymology / Q000209:etiology; D000818:Animals; D001846:Bone Development / Q000187:drug effects; D004791:Enzyme Inhibitors / Q000633:toxicity; D005260:Female; D047109:Fetal Development / Q000187:drug effects*; D056572:Histone Deacetylase Inhibitors; D006801:Humans; D006877:Hydroxamic Acids / Q000633:toxicity*; D011247:Pregnancy; D011817:Rabbits; D051381:Rats; D013723:Teratogens / Q000633:toxicity; D000077337:Vorinostat
D004791:Enzyme Inhibitors; D056572:Histone Deacetylase Inhibitors; D006877:Hydroxamic Acids; D013723:Teratogens; D000077337:Vorinostat