Loss of secreted frizzled-related protein-1 expression in renal cell carcinoma reveals a critical tumor suppressor function.
Rubin
Jeffrey S
JS
Laboratory of Cellular and Molecular Biology and Urologic Oncology Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland 20892-1107, USA.
Bottaro
Donald P
DP
D002292:Carcinoma, Renal Cell / Q000737:chemistry / Q000517:prevention & control*; D006023:Glycoproteins / Q000032:analysis / Q000502:physiology*; D006801:Humans; D047908:Intracellular Signaling Peptides and Proteins; D007680:Kidney Neoplasms / Q000737:chemistry / Q000517:prevention & control*; D025521:Tumor Suppressor Proteins / Q000502:physiology*; D051794:Von Hippel-Lindau Tumor Suppressor Protein / Q000502:physiology; D000099274:Frizzled-Related Proteins
D006023:Glycoproteins; D047908:Intracellular Signaling Peptides and Proteins; D025521:Tumor Suppressor Proteins; D051794:Von Hippel-Lindau Tumor Suppressor Protein; D000099274:Frizzled-Related Proteins; C497446:VHL protein, human