title: Bone welding--a histological evaluation in the jaw.
abstract: The expansion of biodegradable osteosynthesis systems in clinical application correlates well to the progress in development of new materials as to the improvement of application methods. One of those new application methods is the ultrasound-aided insertion of Resorb-X pins. The aim of this study was the histological evaluation of possible thermal damage to bone due to the ultrasound insertion. For this purpose, condylar neck fractures in 12 sheep were produced, repositioned and fixed by Resorb-X plates and pins. The animals were sacrificed in two groups, one after 2 weeks and one after 9 weeks. The bone-pin interlinkage and the structure of the bone were histologically evaluated. After 2 weeks a tight bone-polymer interlinkage was seen. Neither a pronounced foreign body reaction nor an interposition of fibrous tissue at the interface or a thermally induced necrosis was observed. The late phase of wound healing after 9 weeks showed pathomorphological characteristics within the normal range of bone healing. The bone seemed to be free of any alteration caused by process engineering. We conclude that thermal stress caused by ultrasound-aided pin insertion does not lead to cellular reaction in the bone. The fast and easy application of this improved biodegradable osteosynthesis system will bring a clear advantage in clinical use.
authors: Department of Oral and Maxillofacial Surgery, Medical Faculty Carl Gustav Carus, Technische Universitaet Dresden, Fetscherstrasse 74, D-01307 Dresden, Germany. Ronald.Mai@uniklinikum-dresden.de
authors: Ronald
authors: R
authors: Mai
authors: Günter
authors: G
authors: Lauer
authors: Eckart
authors: E
authors: Pilling
authors: Roland
authors: R
authors: Jung
authors: Henry
authors: H
authors: Leonhardt
authors: Peter
authors: P
authors: Proff
authors: Bernd
authors: B
authors: Stadlinger
authors: Winnie
authors: W
authors: Pradel
authors: Uwe
authors: U
authors: Eckelt
authors: Jochen
authors: J
authors: Fanghänel
authors: Tomas
authors: T
authors: Gedrange
mesh_terms: D000818:Animals; D001858:Bone Nails; D001862:Bone Resorption; D004195:Disease Models, Animal; D005592:Fracture Fixation; D050723:Fractures, Bone / Q000601:surgery*; D007568:Jaw; D008335:Mandibular Condyle; D008337:Mandibular Fractures / Q000601:surgery; D012756:Sheep; D014945:Wound Healing