Autophagy: from phenomenology to molecular understanding in less than a decade.
In 2000, it was suggested to me that "Autophagy will be the wave of the future; it will become the new apoptosis." Few people would have agreed at the time, but this statement turned out to be prophetic, and this process of 'self-eating' rapidly exploded as a research field, as scientists discovered connections to cancer, neurodegeneration and even lifespan extension. Amazingly, the molecular breakthroughs in autophagy have taken place during only the past decade.
Klionsky
Daniel J
DJ
Life Sciences Institute, University of Michigan, 210 Washtenaw Avenue, Ann Arbor, Michigan 48109-2216, USA. klionsky@umich.edu
D000818:Animals; D001343:Autophagy; D004194:Disease; D006262:Health; D006728:Hormones / Q000378:metabolism; D006801:Humans; D010588:Phagosomes / Q000648:ultrastructure
D006728:Hormones