Spatial complexity and control of a bacterial cell cycle.
A major breakthrough in understanding the bacterial cell cycle is the discovery that bacteria exhibit a high degree of intracellular organization. Chromosomal loci and many protein complexes are positioned at particular subcellular sites. In this review, we examine recently discovered control mechanisms that make use of dynamically localized protein complexes to orchestrate the Caulobacter crescentus cell cycle. Protein localization, notably of signal transduction proteins, chromosome partition proteins, and proteases, serves to coordinate cell division with chromosome replication and cell differentiation. The developmental fate of daughter cells is decided before completion of cytokinesis, via the early establishment of cell polarity by the distribution of activated signaling proteins, bacterial cytoskeleton, and landmark proteins.
Collier
Justine
J
Department of Developmental Biology, School of Medicine, Beckman Center, Stanford University, Stanford, CA 94305, USA.
Shapiro
Lucy
L
D001426:Bacterial Proteins / Q000235:genetics / Q000378:metabolism; D016934:Caulobacter / Q000166:cytology* / Q000235:genetics / Q000378:metabolism; D002453:Cell Cycle; D015964:Gene Expression Regulation, Bacterial; D008954:Models, Biological; D015398:Signal Transduction
D001426:Bacterial Proteins
Proc Natl Acad Sci U S A. 2002 Apr 2;99(7):4632-7
11930012
Cell. 1996 Jan 12;84(1):83-93
8548829
EMBO J. 2002 Sep 2;21(17):4420-8
12198144
Cell. 1997 Aug 8;90(3):415-24
9267022
Proc Natl Acad Sci U S A. 1998 Jan 6;95(1):120-5
9419339
EMBO J. 1998 Oct 1;17(19):5658-69
9755166
J Bacteriol. 1999 Apr;181(8):2430-9
10198005
Proc Natl Acad Sci U S A. 1999 Sep 14;96(19):10661-6
10485882
Proc Natl Acad Sci U S A. 2004 Nov 9;101(45):15921-6
15522969
J Bacteriol. 2005 Jan;187(2):544-53
15629926
Mol Microbiol. 2005 Feb;55(4):1085-103
15686556
Mol Microbiol. 2005 Feb;55(4):1233-45
15686567
Curr Opin Microbiol. 2005 Apr;8(2):135-42
15802243
J Bacteriol. 2005 Jul;187(14):5000-2
15995216
J Bacteriol. 2005 Oct;187(20):6874-82
16199556
Mol Microbiol. 2005 Dec;58(5):1340-53
16313620
Mol Microbiol. 2006 Jan;59(1):301-16
16359336
EMBO J. 2006 Jan 25;25(2):377-86
16395329
EMBO J. 2006 Jan 25;25(2):346-56
16395331
Cell. 2006 Feb 10;124(3):535-47
16469700
Cell. 2006 Mar 10;124(5):1011-23
16530047
Cell. 2006 Mar 10;124(5):1025-37
16530048
Cell. 2006 Jul 14;126(1):147-62
16839883
Proc Natl Acad Sci U S A. 2006 Jul 18;103(29):10935-40
16829582
Proc Natl Acad Sci U S A. 2006 Jul 18;103(29):10929-34
16829583
Mol Microbiol. 2006 Oct;62(1):5-14
16987173
Trends Biochem Sci. 2006 Dec;31(12):687-93
17084632
Nature. 2006 Dec 14;444(7121):899-904
17136100
Mol Cell. 1999 Nov;4(5):683-94
10619016
Science. 2000 Dec 15;290(5499):2144-8
11118148
Mol Microbiol. 2001 Apr;40(2):485-97
11309130
Proc Natl Acad Sci U S A. 2002 Oct 1;99(20):13160-5
12237413
Proc Natl Acad Sci U S A. 2002 Oct 15;99(21):13831-6
12370432
Mol Microbiol. 2003 Feb;47(4):929-41
12581350
Mol Microbiol. 2003 Mar;47(5):1279-90
12603734
Proc Natl Acad Sci U S A. 2003 Jul 8;100(14):8235-40
12824468
Mol Microbiol. 2003 Oct;50(1):45-60
14507362
Science. 2004 May 14;304(5673):983-7
15087506
Proc Natl Acad Sci U S A. 2004 Jun 8;101(23):8643-8
15159537
Proc Natl Acad Sci U S A. 2004 Jun 22;101(25):9257-62
15178755
Cell. 2004 Sep 3;118(5):579-90
15339663
Proc Natl Acad Sci U S A. 2002 Jun 25;99(13):8701-6
12060714