Iridoids from the green leaves of Eucommia ulmoides.
The bark of Eucommia ulmoides is a well-known crude drug in oriental medicine, and its leaves have been consumed as a beverage. From the green leaves of this plant, three new iridoids (1-3) were isolated, together with 12 known compounds. Compound 1 is the first iridoid possessing a saturated bond between C-3 and C-4 and having an ether linkage between C-3 and C-2 of the glucose unit. Furthermore, 2 and 3 may be regarded as the first naturally occurring conjugates of an iridoid and an amino acid.
Takamura
Chika
C
Faculty of Medical and Pharmaceutical Sciences, Kumamoto University, 5-1 Oe-honmachi, Kumamoto 862-0973, Japan.
Hirata
Tetsuya
T
Ueda
Taro
T
Ono
Masateru
M
Miyashita
Hiroyuki
H
Ikeda
Tsuyoshi
T
Nohara
Toshihiro
T
D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification*; D031283:Eucommiaceae / Q000737:chemistry*; D039823:Iridoids / Q000737:chemistry / Q000302:isolation & purification*; D008518:Medicine, East Asian Traditional; D015394:Molecular Structure; D018515:Plant Leaves / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*
D004365:Drugs, Chinese Herbal; D039823:Iridoids; C523030:eucomoside A; C523031:eucomoside B; C523032:eucomoside C