Marker-assisted selection: an approach for precision plant breeding in the twenty-first century.
DNA markers have enormous potential to improve the efficiency and precision of conventional plant breeding via marker-assisted selection (MAS). The large number of quantitative trait loci (QTLs) mapping studies for diverse crops species have provided an abundance of DNA marker-trait associations. In this review, we present an overview of the advantages of MAS and its most widely used applications in plant breeding, providing examples from cereal crops. We also consider reasons why MAS has had only a small impact on plant breeding so far and suggest ways in which the potential of MAS can be realized. Finally, we discuss reasons why the greater adoption of MAS in the future is inevitable, although the extent of its use will depend on available resources, especially for orphan crops, and may be delayed in less-developed countries. Achieving a substantial impact on crop improvement by MAS represents the great challenge for agricultural scientists in the next few decades.
Collard
Bertrand C Y
BC
Plant Breeding, Genetics and Biotechnology Division, International Rice Research Institute (IRRI), DAPO Box 7777, Metro Manila, The Philippines.
Mackill
David J
DJ
D000383:Agriculture / Q000379:methods*; D018556:Crops, Agricultural / Q000235:genetics* / Q000254:growth & development; D005819:Genetic Markers; D014644:Genetic Variation; D006801:Humans; D030821:Plants, Genetically Modified; D040641:Quantitative Trait Loci; D012641:Selection, Genetic
D005819:Genetic Markers
Nature. 2002 Aug 8;418(6898):678-84
12167874
Philos Trans R Soc Lond B Biol Sci. 2005 Jul 29;360(1459):1503-11
16048792
Nat Genet. 2005 Jun;37 Suppl:S5-10
15920530
Nat Rev Genet. 2001 Dec;2(12):930-42
11733746
Theor Appl Genet. 2005 May;110(8):1467-72
15809850
Theor Appl Genet. 2003 Feb;106(3):559-67
12589557
Curr Opin Plant Biol. 2002 Apr;5(2):94-100
11856602
Pharmacogenomics J. 2003;3(2):77-96
12746733
Genetics. 1998 May;149(1):383-403
9584111
Theor Appl Genet. 2006 Jan;112(2):208-21
16208503
Nucleic Acids Res. 2003 Jan 1;31(1):183-6
12519977
Hereditas. 2004;140(1):61-9
15032948
Theor Appl Genet. 2002 Dec;106(1):1-8
12582865
Plant Physiol. 2002 Dec;130(4):1606-13
12481044
Annu Rev Plant Biol. 2003;54:357-74
14502995
Theor Appl Genet. 2005 Feb;110(4):640-8
15723273
Heredity (Edinb). 1998 Feb;80 ( Pt 2):137-42
9503632
Plant Physiol. 2001 Mar;125(3):1166-74
11244096
Theor Appl Genet. 2004 Oct;109(6):1247-60
15300383
Nucleic Acids Res. 2001 Feb 15;29(4):E25
11160945
Trends Biotechnol. 2003 Feb;21(2):59-63
12573853
Genetics. 2006 Feb;172(2):1165-77
16079235
Theor Appl Genet. 2005 Sep;111(5):838-45
16034585
Genetics. 1996 Dec;144(4):1923-32
8978075
Theor Appl Genet. 2003 Sep;107(5):947-57
12830388
Genetics. 2004 Sep;168(1):513-23
15454561
Genetics. 1997 Nov;147(3):1469-85
9383086
Theor Appl Genet. 2003 Nov;107(7):1331-6
12928781
Plant Mol Biol. 2005 Mar;57(4):461-85
15821975
Genetics. 2002 Dec;162(4):1945-59
12524362
Science. 1998 Oct 23;282(5389):656-9
9784118
Trends Plant Sci. 2003 Jul;8(7):330-4
12878017
Plant Dis. 2001 May;85(5):506-512
30823126
Trends Biotechnol. 2005 Jan;23(1):48-55
15629858
Trends Plant Sci. 2006 May;11(5):213-6
16617032
Genetics. 1990 Mar;124(3):743-56
1968875
Trends Plant Sci. 2003 Sep;8(9):413-6
13678907
Theor Appl Genet. 2004 Jul;109(2):261-71
15057418
Theor Appl Genet. 1993 Nov;87(3):392-401
24190268
Nucleic Acids Res. 2002 Jan 1;30(1):103-5
11752266
Nature. 1988 Oct 20;335(6192):721-6
2902517
Proc Natl Acad Sci U S A. 1999 May 25;96(11):5960-7
10339524
Theor Appl Genet. 2003 Jan;106(2):326-31
12582859
Annu Rev Genet. 1993;27:205-33
8122902
Genome Biol. 2005;6(6):R54
15960806
Theor Appl Genet. 2003 Dec;108(1):141-53
12961067
Theor Appl Genet. 1995 Aug;91(3):448-56
24169834
Theor Appl Genet. 2003 Sep;107(5):922-30
12845434
Nat Rev Genet. 2002 Jan;3(1):22-32
11823788
Theor Appl Genet. 1996 Feb;92(2):191-203
24166168