Towards a continuous dynamic kinetic resolution of 1-phenylethylamine using a membrane assisted, two vessel process.
A continuous process with two separated reaction vessels provides a solution to the problems surrounding the combination of two catalysts in dynamic kinetic resolution reactions by retaining the biocatalyst in a lower temperature vessel with a microfiltration membrane and allowing the racemisation to occur efficiently in a higher temperature vessel.
Roengpithya
Chayaporn
C
Department of Chemical Engineering and Chemical Technology, South Kensington Campus, Imperial College, London, UK.
Patterson
Darrell A
DA
Livingston
Andrew G
AG
Taylor
Paul C
PC
Irwin
Jacob L
JL
Parrett
Mark R
MR