title: Diagnosis of adenoid cystic carcinoma of the lung by bronchial brushing: a case report.
abstract: BACKGROUND
  A diagnosis of pulmonary adenoid cystic carcinoma on exfoliative cytology specimen is very uncommon. The diagnostic cytologic material typically is obtained following a tissue biopsy. No previous report of the diagnosis has been made on bronchial brushing cytologic material when the procedure preceded a tissue biopsy.
  
  
  METHODS
  A 44-year-old man who used to smoke cigarettes and was otherwise well complained of persistent cough for the past 6 months. A chest radiograph revealed a mass lesion in the left hilum. Computed tomography of the chest disclosed an irregular and spiculated soft tissue mass in the left apical anterior segment. Bronchial brushing via bronchoscope was performed, revealing carcinoma cells consistent with an adenoid cystic carcinoma on cytology. A bronchial biopsy and subsequent left upper lobectomy were performed, confirming the diagnosis of adenoid cystic carcinoma of the lung associated with tumor extension to the epithelial surface.
  
  
  CONCLUSIONS
  A diagnosis of bronchial adenoid cystic carcinoma is possible on bronchial brushing. However, as a method in exfoliative cytology, the usefulness of bronchial brushing in diagnosing this tumor is limited by the neoplasm's proximity to the mucosal surface and whether the mucosa has been breached.
authors: Department of Pathology, Singapore General Hospital, Outram Road, Singapore, Singapore. gzzckl@singnet.com.sg
authors: Khoon Leong
authors: KL
authors: Chuah
authors: Kiat Hon
authors: KH
authors: Lim
authors: Mariko Siyue
authors: MS
authors: Koh
authors: Hong Wui
authors: HW
authors: Tan
authors: Wai Ming
authors: WM
authors: Yap
mesh_terms: D000328:Adult; D001485:Basement Membrane / Q000473:pathology; D001706:Biopsy; D018893:Bronchoalveolar Lavage; D001999:Bronchoscopy; D003528:Carcinoma, Adenoid Cystic / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis* / Q000473:pathology; D008297:Male; D014057:Tomography, X-Ray Computed