The influence of the cationic of quaternized chitosan on antifungal activity.
Quaternized chitosan: N-(2-hydroxyl-phenyl)-N,N-dimethyl chitosan (NHPDCS), N-(5-chloro-2-hydroxyl-phenyl)-N,N-dimethyl chitosan (NCHPDCS), N-(2-hydroxyl-5-nitro-phenyl)-N,N-dimethyl chitosan (NHNPDCS) and N-(5-bromic-2-hydroxyl-phenyl)-N,N-dimethyl chitosan (NBHPDCS) were synthesized and their antifungal activities against Botrytis cinerea Pers. (B. cinerea Pers.) and Colletotrichum lagenarium (Pass) Ell.et halst (C. lagenarium (Pass) Ell.et halst) were investigated. The results indicated that the quaternized chitosan derivatives had better inhibitory effects than chitosan, and the antifungal activities should be affected by the cation in these compounds.
Guo
Zhanyong
Z
Institute of Oceanology, Chinese Academy of Sciences, Qingdao, 266071, China.
Xing
Ronge
R
Liu
Song
S
Zhong
Zhimei
Z
Ji
Xia
X
Wang
Lin
L
Li
Pengcheng
P
D000935:Antifungal Agents / Q000494:pharmacology*; D020171:Botrytis / Q000187:drug effects*; D048271:Chitosan / Q000031:analogs & derivatives / Q000138:chemical synthesis / Q000494:pharmacology*; D020231:Colletotrichum / Q000187:drug effects*; D015169:Colony Count, Microbial; D004305:Dose-Response Relationship, Drug; D005506:Food Contamination / Q000517:prevention & control; D005516:Food Microbiology; D006801:Humans; D008826:Microbial Sensitivity Tests; D000644:Quaternary Ammonium Compounds / Q000138:chemical synthesis / Q000494:pharmacology*
D000935:Antifungal Agents; D000644:Quaternary Ammonium Compounds; D048271:Chitosan