title: Parametric equations to represent the profile of the human intervertebral disc in the transverse plane.
abstract: Computational and finite element models of the spine are used to investigate spine and disc mechanics. Subject specific data for the transverse profile of the disc could improve the geometric accuracy of these models. The current study aimed to develop a mathematical algorithm to describe the profile of the disc components, using subject-specific data points. Using data points measured from pictures of human intervertebral discs sectioned in the transverse plane, parametric formulae were derived that mapped the outer profile of the anulus and nucleus. The computed anulus and nucleus profile were a similar shape to the discs from which they were derived. The computed total disc area was similar to the experimental data. The nucleus:disc area ratios were sensitive to the data points defined for each disc. The developed formulae can be easily implemented to provide patient specific data for the disc profile in computational models of the spine.
authors: School of Engineering Systems, Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Australia. j2.little@qut.edu.au
authors: J Paige
authors: JP
authors: Little
authors: M J
authors: MJ
authors: Pearcy
authors: G J
authors: GJ
authors: Pettet
mesh_terms: D000465:Algorithms; D006801:Humans; D007090:Image Interpretation, Computer-Assisted; D007403:Intervertebral Disc / Q000033:anatomy & histology*; D008953:Models, Anatomic
references: J Orthop Res. 2002 Sep;20(5):1121-8
references: 12382981
references: Med Eng Phys. 2001 Apr;23(3):155-64
references: 11410380
references: Spine (Phila Pa 1976). 1992 Mar;17(3):299-306
references: 1566168
references: J Biomech. 2007;40(12):2744-51
references: 17383659
references: Med Biol Eng Comput. 2006 Aug;44(8):633-41
references: 16937205
references: Med Eng Phys. 1999 Dec;21(10 ):689-700
references: 10717549
references: Clin Biomech (Bristol, Avon). 2002 Jul;17(6):439-45
references: 12135545
references: Comput Methods Biomech Biomed Engin. 2008 Feb;11(1):95-103
references: 17943481
references: Proc Inst Mech Eng H. 2002;216(5):281-98
references: 12365787
references: Proc Inst Mech Eng H. 2002;216(5):299-314
references: 12365788
references: Clin Biomech (Bristol, Avon). 2005 Nov;20(9):923-31
references: 16061317
references: Comput Methods Programs Biomed. 1999 Jun;59(3):159-66
references: 10386765
references: Spine (Phila Pa 1976). 1993 Oct 15;18(14):2088-96
references: 8272965
references: Spine (Phila Pa 1976). 1997 Nov 15;22(22):2641-6
references: 9399450
references: Spine (Phila Pa 1976). 1998 Jul 15;23(14):1517-22; discussion 1522-3
references: 9682307
references: Osteoarthritis Cartilage. 1999 Jan;7(1):95-109
references: 10367018
references: Med Biol Eng Comput. 2005 Jul;43(4):465-72
references: 16255428
references: Med Biol Eng Comput. 2007 May;45(5):467-73
references: 17370098
references: Comput Aided Surg. 2004;9(1-2):17-25
references: 15792933
references: J Orthop Sci. 2002;7(2):243-6
references: 11956986
references: Clin Biomech (Bristol, Avon). 2006 May;21(4):337-44
references: 16439042
references: J Biomech. 1974 Nov;7(6):497-507
references: 4452675
references: Spine (Phila Pa 1976). 1988 Sep;13(9):1003-11
references: 3061028