title: Agladupols A-E, triterpenoids from Aglaia duperreana.
abstract: Three new apotirucallane-type triterpenoids, agladupols A-C (1- 3), and two new tirucallane-type triterpenoids, agladupols D and E (4 and 5), along with four known compounds, were isolated from the leaves and stems of Aglaia duperreana (Meliaceae). The structures of compounds 1- 5 were elucidated by spectroscopic data. A (13)C NMR-based general rule for assignment of the C-21 configuration in the side chain of apotirucallane- and tirucallane-type triterpenoids was proposed. According to this, the relative stereochemistry of 21- O-methyltoosendanpentol (1a), a known compound with the relative configurations of the stereocenters in the side chain undetermined, was completely assigned.
authors: State Key Laboratory fo Drug Research, Institute of Materia Medica, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, People's Republic of China.
authors: Bo-Jun
authors: BJ
authors: Xie
authors: Sheng-Ping
authors: SP
authors: Yang
authors: Hua-Dong
authors: HD
authors: Chen
authors: Jian-Min
authors: JM
authors: Yue
mesh_terms: D031602:Aglaia / Q000737:chemistry*; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification*; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D018515:Plant Leaves / Q000737:chemistry; D018547:Plant Stems / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification*
chemical_list: D004365:Drugs, Chinese Herbal; D014315:Triterpenes