Intake of vitamin A-rich foods and lung cancer risk in Taiwan: with special reference to garland chrysanthemum and sweet potato leaf consumption.
A case-control study was conducted to investigate the association between the consumption of local common foods that are rich in vitamin A and the risk of lung cancer in Taiwan. A total of 301 incident lung cancer cases, 602 hospital controls, and 602 neighborhood controls were recruited. The consumption of 13 food items and vitamin supplements was estimated by use of a food frequency questionnaire. The conditional logistic regression models were used to estimate the adjusted odds ratios (AOR) and 95% confidence intervals (CI) for lung cancer risk with each control group as reference by adjustment of covariates. A reduced risk for lung cancer was found to be associated with increased intakes of vitamin A, alpha-carotene, and beta-carotene from 13 food items. More servings of vegetables (AOR for the highest versus the lowest quartile = 0.67-0.70, 95% CI = 0.42-1.08, (plinear trend )= 0.04), garland chrysanthemum (AOR for the highest versus the lowest tertile = 0.58-0.74, 95% CI = 0.37-1.14, (plinear trend )<= 0.04) and sweet potato leaves (AOR for the highest versus the lowest tertile = 0.43-0.65, 95% CI = 0.28-0.96, (plinear trend )<= 0.03) were associated with the reduced risk for lung cancer. In conclusion, higher consumption of vitamin A-rich vegetables, especially garland chrysanthemum and sweet potato leaves might provide potential protection from lung cancer.
Jin
Yi-Ru
YR
Department of Medical Education and Research, Kaohsiung Veterans General Hospital, 386 Ta-Chung 1st Rd., Kaohsiung, Taiwan.
Lee
Meei-Shyuan
MS
Lee
Jang-Hwa
JH
Hsu
Hon-Ki
HK
Lu
Jau-Yeong
JY
Chao
Shin-Shin
SS
Chen
Kow-Tong
KT
Liou
Saou-Hsing
SH
Ger
Luo-Ping
LP
D000368:Aged; D016022:Case-Control Studies; D031202:Chrysanthemum / Q000737:chemistry*; D016001:Confidence Intervals; D004032:Diet; D005260:Female; D005504:Food Analysis; D006801:Humans; D027723:Ipomoea batatas / Q000737:chemistry*; D016015:Logistic Models; D008175:Lung Neoplasms / Q000453:epidemiology* / Q000209:etiology; D008297:Male; D008875:Middle Aged; D015596:Nutrition Assessment; D016017:Odds Ratio; D018515:Plant Leaves / Q000737:chemistry; D012307:Risk Factors; D012907:Smoking / Q000009:adverse effects; D011795:Surveys and Questionnaires; D013624:Taiwan / Q000453:epidemiology; D014801:Vitamin A / Q000008:administration & dosage*
D014801:Vitamin A