Pediatric hospitalization for pneumococcal diseases preventable by 7-valent pneumococcal conjugate vaccine in Hong Kong.
In a population-based study, we use ICD-9-CM codes to estimate the hospitalization rates for pneumococcal disease among young children in Hong Kong, 2000-2005 and the preventable burden using several outcome indicators. For children aged </=2 years, the average admission rates (per 100,000 person-years) were 23.7 for invasive pneumococcal disease (IPD), 1047.5 for clinical pneumonia and 213 for radiological pneumonia. For this group of children, the disease burden potentially preventable by vaccination, per 100,000 person-years, were estimated to be 19.3 (95% CI, 16.7-21.9) for IPD, 58.5 (95% CI, 57.3-59.6) for clinical pneumonia and 40.6 (95% CI, 59-82.2) for radiological pneumonia.
Ho
Pak-Leung
PL
Department of Microbiology, Queen Mary Hospital, University of Hong Kong, Pokfulam Road, Pokfulam, Hong Kong, SAR, China. plho@hkucc.hku.hk
Chiu
Susan S
SS
Chow
Frankie K H
FK
Mak
Gannon C
GC
Lau
Yu Lung
YL
D016470:Bacteremia / Q000453:epidemiology / Q000517:prevention & control; D002675:Child, Preschool; D006723:Hong Kong / Q000453:epidemiology; D006760:Hospitalization / Q000706:statistics & numerical data*; D006801:Humans; D015994:Incidence; D007223:Infant; D007231:Infant, Newborn; D038801:International Classification of Diseases; D008586:Meningitis, Pneumococcal / Q000453:epidemiology / Q000517:prevention & control; D011008:Pneumococcal Infections / Q000453:epidemiology* / Q000517:prevention & control*; D022242:Pneumococcal Vaccines / Q000008:administration & dosage*; D011018:Pneumonia, Pneumococcal / Q000453:epidemiology / Q000517:prevention & control; D013296:Streptococcus pneumoniae / Q000276:immunology; D018074:Vaccines, Conjugate / Q000008:administration & dosage*
D022242:Pneumococcal Vaccines; D018074:Vaccines, Conjugate