Personalized nutrition: nutritional genomics as a potential tool for targeted medical nutrition therapy.
An emerging goal of medical nutrition therapy is to tailor dietary advice to an individual's genetic profile. In the United States and elsewhere, "nutrigenetic" services are available over the Internet without the direct involvement of a health care professional. Among the genetic variants most commonly assessed by these companies are those found in genes that influence cardiovascular disease risk. However, the interpretation of DNA-based data is complex. The goal of this paper is to carefully examine nutritional genomics as a potential tool for targeted medical nutrition therapy. The approach is to use heart health susceptibility genes and their common genetic variants as the model.
Vakili
Sina
S
Human Nutrition and Food Science Department, Cal Poly Pomona, 3801 W. Temple Ave., Pomona, CA 91768, USA.
Caudill
Marie A
MA
D002318:Cardiovascular Diseases / Q000235:genetics / Q000517:prevention & control; D004032:Diet; D005786:Gene Expression Regulation; D014644:Genetic Variation; D023281:Genomics; D006801:Humans; D044623:Nutrition Therapy / Q000379:methods / Q000592:standards*; D009747:Nutritional Physiological Phenomena / Q000235:genetics* / Q000502:physiology