Arabidopsis thaliana inositol 1,3,4-trisphosphate 5/6-kinase 4 (AtITPK4) is an outlier to a family of ATP-grasp fold proteins from Arabidopsis.
The Arabidopsis genome encodes a family of inositol 1,3,4-trisphosphate 5/6-kinases which form a subgroup of a larger group of ATP-grasp fold proteins. An analysis of the inositol 1,3,4-trisphosphate 5/6-kinase family might, ultimately, be best rewarded by detailed comparison of related enzymes in a single genome. The enzyme encoded by At2G43980, AtITPK4; is an outlier to its family. At2G43980 is expressed in male and female organs of young and mature flowers. AtITPK4 differs from other family members in that it does not display inositol 3,4,5,6-tetrakisphosphate 1-kinase activity; rather, it displays inositol 1,4,5,6-tetrakisphosphate and inositol 1,3,4,5-tetrakisphosphate isomerase activity.
Sweetman
Dylan
D
School of Biological Sciences, University of East Anglia, Earlham Road, Norwich, Norfolk, UK.
Stavridou
Ioanna
I
Johnson
Sue
S
Green
Porntip
P
Caddick
Samuel E K
SE
Brearley
Charles A
CA
D000255:Adenosine Triphosphate / Q000378:metabolism*; D000595:Amino Acid Sequence; D017360:Arabidopsis / Q000201:enzymology* / Q000235:genetics; D029681:Arabidopsis Proteins / Q000737:chemistry* / Q000235:genetics / Q000378:metabolism*; D035264:Flowers / Q000166:cytology / Q000201:enzymology; D020869:Gene Expression Profiling; D018506:Gene Expression Regulation, Plant; D005966:Glucuronidase / Q000378:metabolism; D017403:In Situ Hybridization; D007700:Kinetics; D008969:Molecular Sequence Data; D017853:Phosphotransferases (Alcohol Group Acceptor) / Q000737:chemistry* / Q000235:genetics / Q000378:metabolism*; D011401:Promoter Regions, Genetic / Q000235:genetics; D017433:Protein Structure, Secondary; D011994:Recombinant Proteins / Q000378:metabolism; D017386:Sequence Homology, Amino Acid; D013379:Substrate Specificity
D029681:Arabidopsis Proteins; D011994:Recombinant Proteins; D000255:Adenosine Triphosphate; C523492:inositol 1,3,4-trisphosphate 5-6-kinase 4, Arabidopsis; D017853:Phosphotransferases (Alcohol Group Acceptor); D005966:Glucuronidase