title: [High risk lesions of the oral mucosa--Diagnosis, therapy and follow-up in two cases].
abstract: Stomatologic lesions at risk to develop an oral squamous cell carcinoma (OSCC) such as oral leukoplakia, erythroplakia/erythroleukoplakia, or oral lichen planus, need an early detection, diagnosis and a long-term/lifelong follow-up to prevent malignant transformation. In the following report, two patients are presented with oral mucosal lesions, who were referred, diagnosed, treated, and underwent follow-up examinations at the Stomatology Service of the Department of Oral Surgery and Stomatology at the University of Bern. These two cases emphasize the importance of early detection and managment of precancerous lesions or initial stages of OSCC. Additionally, risk factors, such as tobacco and alcohol consumption and their influence on stomatologic lesions and their prognosis, will be discussed.
authors: Klinik für Oralchirurgie und Stomatologie, Zahnmedizinische Kliniken der Universität Bern.
authors: Sandro A
authors: SA
authors: Halbritter
authors: Peter
authors: P
authors: Spieler
authors: Michael M
authors: MM
authors: Bornstein
mesh_terms: D000328:Adult; D000428:Alcohol Drinking; D002294:Carcinoma, Squamous Cell / Q000473:pathology*; D004273:DNA, Neoplasm / Q000032:analysis; D042241:Early Diagnosis; D006801:Humans; D007972:Leukoplakia, Oral / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009061:Mouth Mucosa / Q000473:pathology; D009062:Mouth Neoplasms / Q000473:pathology*; D011230:Precancerous Conditions / Q000473:pathology*; D012307:Risk Factors; D012907:Smoking
chemical_list: D004273:DNA, Neoplasm