Hepatorenal syndrome.
Hepatorenal syndrome (HRS) is a "functional" and reversible form of renal failure that occurs in patients with advanced chronic liver disease. The distinctive hallmark feature of HRS is the intense renal vasoconstriction caused by interactions between systemic and portal hemodynamics. This results in activation of vasoconstrictors and suppression of vasodilators in the renal circulation. Epidemiology, pathophysiology, as well as current and emerging therapies of HRS are discussed in this review.
Turban
Sharon
S
Division of Nephrology, Johns Hopkins University, 1830 East Monument Street, Suite 416, Baltimore, Maryland 21205, USA.
Thuluvath
Paul J
PJ
Atta
Mohamed G
MG
D006530:Hepatorenal Syndrome / Q000175:diagnosis / Q000503:physiopathology* / Q000628:therapy*; D006801:Humans; D016031:Liver Transplantation; D011379:Prognosis; D006435:Renal Dialysis; D014662:Vasoconstrictor Agents / Q000627:therapeutic use
D014662:Vasoconstrictor Agents
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