title: A 12-year review of cases of adult tetanus managed at the University College Hospital, Ibadan, Nigeria.
abstract: In this review, hospital case records of 202 adult tetanus managed between January 1990 and December 2001 in a tertiary institution in Southwestern Nigeria were reviewed. The mean age of the patients was 36.1+/-17.8 years with male:female ratio of 2.2:1 and an overall mortality rate of 64%. Patients with unfavourable outcomes spent 4.5+/-0.41 days compared with 16.6+/-1.2 days by those who survived. Factors associated with poor prognosis are age >60 years (P=0.029), incubation period <7 days (P=0.007), period of onset <48 h (P=0.0001), tachycardia with pulse rate >120/min (P=0.001) and spasm (P=0.002). Gender (P=0.11), post-injury vaccination (P=0.48) and types of antibiotics administered (P=0.49) were not significantly associated with increased mortality. The three most common complications were aspiration pneumonitis, sepsis and urinary bladder obstruction while complications with highest mortality (100%) were sepsis and cardiac arrest.
authors: Department of Medicine, University of Ilorin Teaching Hospital, Ilorin, Nigeria. emanuelosanya@yahoo.com
authors: E O
authors: EO
authors: Sanya
authors: S S
authors: SS
authors: Taiwo
authors: J K
authors: JK
authors: Olarinoye
authors: A
authors: A
authors: Aje
authors: O O M
authors: OO
authors: Daramola
authors: A
authors: A
authors: Ogunniyi
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006785:Hospitals, University; D006801:Humans; D008297:Male; D008875:Middle Aged; D009549:Nigeria / Q000453:epidemiology; D012189:Retrospective Studies; D015996:Survival Rate; D013742:Tetanus / Q000150:complications / Q000453:epidemiology / Q000401:mortality*