title: Listeria monocytogenes following orthotopic liver transplantation: central nervous system involvement and review of the literature.
abstract: Listeria monocytogene is a well-recognized cause of bacteremia in immunocompromised individuals, including solid organ transplant recipients, but has been rarely reported following orthotopic liver transplantation. We describe a case of listeria meningitis that occurred within a week after liver transplantation. The patient developed a severe headache that mimicked tacrolimus encephalopathy, and was subsequently diagnosed with listeria meningitis by cerebrospinal fluid culture. The infection was successfully treated with three-week course of intravenous ampicillin. Recurrent hepatitis C followed and was successfully treated with interferon alfa and ribavirin. Fourteen cases of listeriosis after orthotopic liver transplantation have been reported in the English literature. Most reported cases were successfully treated with intravenous ampicillin. There were four cases of listeria meningitis, and the mortality of them was 50%. Early detection and treatment of listeria meningitis are the key to obtaining a better prognosis.
authors: Division of Transplantation and Hepatobiliary Surgery, Department of Surgery, University of Florida College of Medicine, PO Box 100286, Gainesville, FL 32610-0286, United States.
authors: Shugo
authors: S
authors: Mizuno
authors: Ivan-R
authors: IR
authors: Zendejas
authors: Alan-I
authors: AI
authors: Reed
authors: Robin-D
authors: RD
authors: Kim
authors: Richard-J
authors: RJ
authors: Howard
authors: Alan-W
authors: AW
authors: Hemming
authors: Denise-C
authors: DC
authors: Schain
authors: Consuelo
authors: C
authors: Soldevila-Pico
authors: Roberto-J
authors: RJ
authors: Firpi
authors: Shiro
authors: S
authors: Fujita
mesh_terms: D000667:Ampicillin / Q000627:therapeutic use; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002490:Central Nervous System / Q000382:microbiology; D006801:Humans; D008089:Listeria monocytogenes; D016031:Liver Transplantation / Q000009:adverse effects*; D008297:Male; D008584:Meningitis, Listeria / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology*; D008875:Middle Aged
chemical_list: D000900:Anti-Bacterial Agents; D000667:Ampicillin
references: Infection. 1990 Mar-Apr;18(2):107-8
references: 2110115
references: Epidemiol Infect. 1991 Feb;106(1):157-66
references: 1993449
references: Infection. 1997 May-Jun;25(3):135-9
references: 9181378
references: J Infect Dis. 1990 Dec;162(6):1316-23
references: 2230261
references: Pediatr Transplant. 2000 May;4(2):156-8
references: 11272610
references: Chirurgie. 1989;115(8):533-9
references: 2700160
references: J Hepatol. 1993 Jul;18(3):284-9
references: 8228121
references: Am J Gastroenterol. 2002 Jun;97(6):1507-11
references: 12094874
references: Rev Infect Dis. 1986 May-Jun;8(3):427-30
references: 3523699
references: Transpl Infect Dis. 1999 Dec;1(4):284-7
references: 11428999
references: Liver. 1998 Jun;18(3):213-5
references: 9716234
references: Mayo Clin Proc. 1989 May;64(5):555-64
references: 2542701
references: Clin Infect Dis. 2006 Nov 15;43(10):1233-8
references: 17051485
references: Am J Epidemiol. 1991 Feb 15;133(4):392-401
references: 1899779
references: J Infect. 2003 Jan;46(1):70-1
references: 12504615
references: Transplant Proc. 2003 Jun;35(4):1485-7
references: 12826201
references: Gastroenterol Clin Biol. 1996;20(8-9):700-2
references: 8977820
references: Rev Infect Dis. 1982 May-Jun;4(3):665-82
references: 6750737
references: Clin Infect Dis. 1992 Apr;14(4):815-21
references: 1341415
references: Ann N Y Acad Sci. 1970 Oct 30;174(2):545-51
references: 4993531
references: Am J Gastroenterol. 1998 Oct;93(10):1942-4
references: 9772060