title: Sapphire platinum detachable coil experience in a tertiary-care facility.
abstract: BACKGROUND
  The Guglielmi Detachable Coil introduced by the Boston Scientific Corporation has been widely used for endovascular coiling of aneurysm. Recently, Sapphire platinum detachable coils (eV3, Irvine, CA) have been introduced for aneurysm coiling. Herein, we report our clinical experience with the Sapphire coil to evaluate the incidence of coil related complications and the rate of aneurysm occlusion.
  
  
  METHODS
  Consecutive patients who underwent embolization with Sapphire detachable coils were prospectively enrolled from January 2004 to September 2004 and the data were retrospectively analyzed. Patient demographics, including age, gender, presenting symptoms, Hunt and Hess grade, Fisher grade and locations of the vascular anomalies were collected. Additionally, complications associated with the coils and rates of aneurysm occlusion were observed and the data compiled.
  
  
  RESULTS
  29 patients underwent Sapphire coil embolization for intracranial aneurysms. Mean age was 50 +/- 18 (mean +/- SD) years with 81% being females. Aneurysm neck reconstruction was required in 7 cases, 6 with Neuroform stent (5 unruptured aneurysms) and 1 with balloon assistance (ruptured aneurysm). In 7 cases, Sapphire coils were used along with other coils. There were no events of thromboembolism or ruptures of aneurysms during coil embolization. However, multi-diameter coils demonstrated stretching in 4 stent-assisted cases without any adverse consequences. Complete occlusion of the aneurysm was achieved in 79.31% of the patients, neck remnant in 6.89, and partial coiling was achieved in 13.79%.
  
  
  CONCLUSIONS
  The Sapphire coil could safely be used in the treatment of both ruptured and unruptured aneurysms. However, multi-diameter non-stretch resistant coils may be associated with coil stretching when used in conjunction with a stent. Further study is still required for definitive results.
authors: Department of Neurology and Neurosurgery, Wayne State University, Detroit, MI, USA. yahia25@hotmail.com
authors: Abutaher M
authors: AM
authors: Yahia
authors: Vickie
authors: V
authors: Gordon
authors: John
authors: J
authors: Whapham
authors: Ali
authors: A
authors: Malek
authors: Mohammed
authors: M
authors: Rehman
authors: Richard D
authors: RD
authors: Fessler
mesh_terms: D000328:Adult; D000368:Aged; D000497:Alloys; D017542:Aneurysm, Ruptured / Q000000981:diagnostic imaging / Q000401:mortality / Q000628:therapy*; D002533:Cerebral Angiography; D016208:Databases, Factual; D004621:Embolization, Therapeutic / Q000009:adverse effects / Q000295:instrumentation* / Q000401:mortality; D005260:Female; D006801:Humans; D002532:Intracranial Aneurysm / Q000000981:diagnostic imaging / Q000401:mortality / Q000628:therapy*; D007495:Iridium; D008297:Male; D008875:Middle Aged; D010984:Platinum; D012189:Retrospective Studies
chemical_list: D000497:Alloys; C013616:nitinol; D007495:Iridium; D010984:Platinum
references: Stroke. 1999 Feb;30(2):470-6
references: 9933290
references: Neurosurgery. 1995 Oct;37(4):640-7; discussion 647-8
references: 8559291
references: Stroke. 2002 Oct;33(10):2536-44
references: 12364750
references: J Neurosurg. 2000 Aug;93(2):175-82
references: 10930001
references: J Neurosurg. 1998 Jul;89(1):81-6
references: 9647176
references: Neurosurgery. 1998 Nov;43(5):1016-25
references: 9802844
references: Stroke. 2001 Mar;32(3):597-605
references: 11239174
references: Radiology. 1999 May;211(2):325-36
references: 10228510
references: Ann Neurol. 2000 Jul;48(1):11-9
references: 10894211
references: AJNR Am J Neuroradiol. 2004 May;25(5):813-8
references: 15140727
references: Stroke. 2000 Jan;31(1):100-10
references: 10625723
references: Neurochirurgie. 2005 Sep;51(3-4 Pt 1):155-64
references: 16389901
references: J Neurosurg. 2000 Oct;93(4):569-80
references: 11014534
references: J Neurosurg. 1993 Jul;79(1):3-10
references: 8315465
references: Stroke. 1999 Dec;30(12 ):2617-22
references: 10582987
references: AJNR Am J Neuroradiol. 2004 Sep;25(8):1368-72
references: 15466334
references: J Neurosurg. 1999 May;90(5):868-74
references: 10223453
references: Stroke. 2000 Oct;31(10):2369-77
references: 11022066
references: Lancet. 2002 Oct 26;360(9342):1267-74
references: 12414200