title: The culprit artery in acute myocardial infarction in different environmental physical activity levels.
abstract: BACKGROUND
  The timing of acute coronary events may be related to endogenous and exogenous--environmental--factors.
  
  
  OBJECTIVE
  To check if daily levels of geomagnetic activity (GMA) and/or cosmic ray activity (CRA) measured by neutron activity (imp/min) on the Earth's surface are related by timing with specific culprit artery of AMI.
  
  
  METHODS
  Data of PCI for AMI (n=904, 696 men) from 01/2000 to 02/2006 (2251 days) were used for analysis. Daily GMA (I-IV levels) and neutron activity in imp/min were compared with localization of the culprit artery in AMI (LAD, RCA, CRX and Diagonal). The principal consideration was concentrated in the most frequent lesions of LAD (n=422) and RCA (n=332). The cosmophysical data were derived from USA, Russia and Finland.
  
  
  RESULTS
  Similar to the whole 2251 days, the PCI were inversely related to GMA (p=0.03) and show a strong tendency to increase at higher CRA (p=0.07). Comparing data on two high (III, IV) and low (I, II) levels of GMA shows that, at high GMA, RCA and LAD lesions were equal; at the more often low daily levels of GMA, accompanied by higher CRA (neutron) activity (p<0.0001), LAD lesions were higher by 30% (chi(2)=-4.064, p=0.04).
  
  
  CONCLUSIONS
  At higher daily levels of GMA, RCA/LAD culprit lesions in AMI are equal; at low GMA and higher CRA (neutron) activity, LAD lesions are predominant.
authors: Elyiahu
authors: E
authors: Stoupel
authors: Abid
authors: A
authors: Assali
authors: Igal
authors: I
authors: Teplitzky
authors: Peter
authors: P
authors: Israelevich
authors: Evgeny
authors: E
authors: Abramson
authors: Jaqueline
authors: J
authors: Sulkes
authors: Ran
authors: R
authors: Kornowski
mesh_terms: D000368:Aged; D003324:Coronary Artery Disease / Q000209:etiology / Q000503:physiopathology; D054059:Coronary Occlusion / Q000209:etiology / Q000503:physiopathology; D003331:Coronary Vessels / Q000503:physiopathology / Q000528:radiation effects*; D003359:Cosmic Radiation / Q000009:adverse effects; D004781:Environmental Exposure / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009043:Motor Activity / Q000528:radiation effects*; D009203:Myocardial Infarction / Q000209:etiology* / Q000503:physiopathology*; D009502:Neutrons / Q000009:adverse effects