title: [Granulocytopenia while using clozapine: continuing or stopping treatment].
abstract: This article describes four patients using clozapine, with neutropenia. Clozapine-induced neutropenia can be one of three types: pseudo, benign or malignant. The malignant type can give cause for serious concern; in that case treatment with clozapine must be stopped. Pseudo-neutropenia and benign neutropenia, however, occur frequently. In these cases it is probably unnecessary to stop clozapine medication, particularly if clozapine is clearly indicated.
authors: High Care van GGZ Haagstreek, onderdeel van Rivierduinen, te Leidschendam. j.bogers@ggzhaagstreek.nl
authors: J P A M
authors: JP
authors: Bogers
mesh_terms: D000328:Adult; D000380:Agranulocytosis / Q000139:chemically induced*; D014150:Antipsychotic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D003024:Clozapine / Q000009:adverse effects* / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009503:Neutropenia / Q000139:chemically induced*
chemical_list: D014150:Antipsychotic Agents; D003024:Clozapine