title: Response of a thymic mucoepidermoid carcinoma to combination chemotherapy with cisplatin and irinotecan: a case report.
abstract: A chemotherapeutic regimen for advanced thymic carcinoma has not yet been established. We describe a patient with advanced thymic mucoepidermoid carcinoma who achieved a complete response to combination chemotherapy with cisplatin (Randa) and irinotecan hydrochloride (Campto). A 74-year-old man was admitted to our hospital because of chest pain, general fatigue, appetite loss and weight loss. Chest computed tomography examinations revealed an anterior mediastinal tumour (5.5cmx3.5cmx9.5cm) that had invaded the subcutis through the sternum. The patient was treated with three courses of cisplatin and irinotecan hydrochloride followed by radiotherapy; he has since exhibited a complete response for 3 months.
authors: Department of Respiratory Medicine, International Medical Center of Japan, 1-21-1 Toyama, Shinjuku-ku, Tokyo 162-8655, Japan. etfusefuse@yahoo.co.jp
authors: Etsu Tsuzuki
authors: ET
authors: Fuse
authors: Mitsuhiro
authors: M
authors: Kamimura
authors: Yuichiro
authors: Y
authors: Takeda
authors: Makoto
authors: M
authors: Kawaishi
authors: Sosuke
authors: S
authors: Kimura
authors: Hitoshi
authors: H
authors: Niino
authors: Kiyoshi
authors: K
authors: Saito
authors: Nobuyuki
authors: N
authors: Kobayashi
authors: Koichiro
authors: K
authors: Kudo
mesh_terms: D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D002166:Camptothecin / Q000008:administration & dosage / Q000031:analogs & derivatives; D018277:Carcinoma, Mucoepidermoid / Q000188:drug therapy* / Q000532:radiotherapy; D002945:Cisplatin / Q000008:administration & dosage; D003131:Combined Modality Therapy; D006801:Humans; D000077146:Irinotecan; D008297:Male; D013953:Thymus Neoplasms / Q000188:drug therapy* / Q000532:radiotherapy
chemical_list: D000077146:Irinotecan; D002945:Cisplatin; D002166:Camptothecin