Treatment of a facial nerve neuroma with fractionated stereotactic radiotherapy.
BACKGROUND
Facial nerve neuromas are extremely rare and are often mistaken for acoustic neuromas when located near the vestibular nerve. Usually presenting with facial weakness and hearing loss, facial nerve neuromas of the cerebellopontine angle have commonly been managed by surgery. We present the first reported case of a facial nerve neuroma treated with fractionated stereotactic radiotherapy (FSRT).


METHODS
The patient was a 40-year-old woman who presented with tinnitus, dizziness and decreased hearing that was associated with a right intracanalicular mass on magnetic resonance imaging (MRI). She underwent a middle fossa craniotomy only to reveal a facial nerve tumor rather than an acoustic neuroma that was not resected due to the high risk of facial paralysis. Following surgery, her facial function worsened and was associated with tumor enlargement on MRI. She was referred for FSRT and received 54 Gy in daily 1.8-Gy fractions with a prescription isodose line of 90%.


RESULTS
Three months after treatment she had no worsening of her pretreatment symptoms, and at the 1-year follow-up, she experienced facial weakness improvement accompanied by an absence of tumor growth on MRI. These clinical and imaging findings persisted at 48 months of follow-up.


CONCLUSIONS
In the first report of a facial nerve neuroma treated with FSRT, this treatment resulted in excellent long-term (4-year) tumor control with improvement of pretreatment symptomatology and absence of morbidity. This report demonstrates the potential for using FSRT to treat facial nerve neuromas of the cerebellopontine angle that could otherwise be associated with significant operative morbidity.
McClelland
Shearwood
S
Department of Neurosurgery, University of Minnesota Medical School, Minneapolis, MN 55455, USA. mccl0285@umn.edu
Dusenbery
Kathryn E
KE
Higgins
Patrick D
PD
Hall
Walter A
WA
D000328:Adult; D002530:Cerebellopontine Angle / Q000000981:diagnostic imaging; D003390:Cranial Nerve Neoplasms / Q000000981:diagnostic imaging / Q000532:radiotherapy* / Q000601:surgery; D003399:Craniotomy; D019583:Dose Fractionation, Radiation; D005154:Facial Nerve / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D009463:Neuroma / Q000000981:diagnostic imaging / Q000532:radiotherapy* / Q000601:surgery; D013238:Stereotaxic Techniques; D014057:Tomography, X-Ray Computed