title: [Case report of cholesterol crystal embolism 1 month after carotid stenting].
abstract: Cholesterol crystal embolism (CCE) is a systemic disease resulting from shedding of cholesterol crystals into the small vessels of multiple organs, including skin, kidney, gastrointestinal tract and others. Recently, neuroendovascular therapeutic procedures for athrosclerosis disease is increasing. We report a case of CCE after carotid stenting (CAS). A 73-year-old man with asymptomatic carotid stenosis was treated by percutanenous transluminal angioplasty with stenting. CAS was achieved in a short time without trouble. About 1 month after CAS, his renal function deteriorated and purpura appeared on both toe tips (blue toe syndrome) with muscle pain of the lower extremities. Under diagnosis of CCE, he was treated by Predonisolone 20 mg/day and Valsartan 160 mg/day, Pravastatin 10 mg/day. His symptom's dramatically improved, with partial recovery of renal function. CCE rarely occurs after angiographic or interventional procedures, but is difficult to diagnose clinically and there is no established therapy. For early diagnosis of CCE strict follow-up of a patients clinical presentation and laboratory data, especially in high risk patients, is needed.
authors: Department of Neurosurgery, Kyoto University Graduate School of Medicine, Japan.
authors: Kazutomo
authors: K
authors: Nakazawa
authors: Tsuyoshi
authors: T
authors: Ohta
authors: Motoaki
authors: M
authors: Fujimoto
authors: Hirotoshi
authors: H
authors: Imamura
authors: Nobuo
authors: N
authors: Hashimoto
mesh_terms: D000368:Aged; D015906:Angioplasty, Balloon, Coronary / Q000009:adverse effects; D016893:Carotid Stenosis / Q000628:therapy; D004359:Drug Therapy, Combination; D042241:Early Diagnosis; D017700:Embolism, Cholesterol / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D006801:Humans; D008297:Male; D017035:Pravastatin / Q000627:therapeutic use; D011239:Prednisolone / Q000627:therapeutic use; D015607:Stents / Q000009:adverse effects*; D013777:Tetrazoles / Q000627:therapeutic use; D013997:Time Factors; D016896:Treatment Outcome; D014633:Valine / Q000031:analogs & derivatives / Q000627:therapeutic use; D000068756:Valsartan
chemical_list: D013777:Tetrazoles; D000068756:Valsartan; D011239:Prednisolone; D014633:Valine; D017035:Pravastatin