Nonprosthesis orthopedic applications of (18)F fluoro-2-deoxy-D-glucose PET in the detection of osteomyelitis.
This article describes the impact of [(18)F]2-fluoro-2-deoxy-D-glucose (FDG) PET in the diagnosis of non-prosthesis-related orthopedic infections and inflammation. FDG-PET has an excellent sensitivity in the detection of osteomyelitis (OM). Early data indicate that FDG-PET may be more specific than MRI in diagnosing OM. The role of the combination of FDG and PET-CT in the diagnosis of OM is likely to be determined as this combination is used on a routine basis. Early data from studies in rheumatoid arthritis indicate that FDG-PET is highly accurate in early diagnosis and that it provides results comparable to the most advanced conventional techniques.
Meller
Johannes
J
Department of Nuclear Medicine, University of Göttingen, Robert Koch-Strasse 40, D- 37075, Göttingen, Germany. jmeller@med.uni-goettingen.de
Sahlmann
Carsten Oliver
CO
Liersch
Torsten
T
Hao Tang
Peter
P
Alavi
Abass
A
D000818:Animals; D019788:Fluorodeoxyglucose F18 / Q000493:pharmacokinetics; D006801:Humans; D010019:Osteomyelitis / Q000000981:diagnostic imaging*; D019275:Radiopharmaceuticals / Q000493:pharmacokinetics; D012008:Recurrence; D012680:Sensitivity and Specificity; D014018:Tissue Distribution; D014055:Tomography, Emission-Computed
D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18