title: The role of the sagittal view of the ductal arch in identification of fetuses with conotruncal anomalies using 4-dimensional ultrasonography.
abstract: OBJECTIVE
  Conotruncal anomalies represent one fifth of all congenital heart defects (CHDs) detected in the fetus. However, the spatial relationship of the great vessels is incorrectly defined in about 20% of these cases. The sagittal view of the ductal arch is considered a standard ultrasonographic view in fetal echocardiography and can be easily visualized using 4-dimensional (4D) ultrasonography. This study was designed to determine the role of this ultrasonographic plane for the prenatal diagnosis of conotruncal anomalies.
  
  
  METHODS
  We reviewed 4D volume data sets, acquired with the spatiotemporal image correlation technique, from fetuses with and without confirmed conotruncal anomalies. The visualization rate of the sagittal view of the ductal arch was compared among groups using standardized multiplanar views.
  
  
  RESULTS
  This study included 183 volume data sets from fetuses in the following groups: (1) normal echocardiographic findings (n = 130); (2) conotruncal anomalies (n = 18); and (3) other CHDs (n = 35). Volumes of poor image quality were excluded from analysis (8.2% [15/183]). The visualization rate of the sagittal view of the ductal arch was significantly lower in fetuses with conotruncal anomalies (5.6% [1/18]) than that in fetuses without abnormalities (93.1% [108/116]) and that in fetuses with other CHDs (79.4% [27/34]; P < .01). Absence of visualization of the sagittal view of the ductal arch was associated with a likelihood ratio of 9.44 (95% confidence interval, 5.8-15.5) to have conotruncal anomalies.
  
  
  CONCLUSIONS
  The sagittal view of the ductal arch may play an important role in the screening and prenatal diagnosis of conotruncal anomalies in 4D ultrasonography.
authors: Perinatology Research Branch, NICHD/NIH/DHHS, Wayne State University/Hutzel Women's Hospital, 3990 John R, Box 4, Detroit, MI 48201 USA. espinoz@med.wayne.edu
authors: Jimmy
authors: J
authors: Espinoza
authors: Roberto
authors: R
authors: Romero
authors: Juan Pedro
authors: JP
authors: Kusanovic
authors: Francesca
authors: F
authors: Gotsch
authors: Offer
authors: O
authors: Erez
authors: Wesley
authors: W
authors: Lee
authors: Luís F
authors: LF
authors: Gonçalves
authors: Mary Lou
authors: ML
authors: Schoen
authors: Sonia S
authors: SS
authors: Hassan
mesh_terms: D000465:Algorithms; D016009:Chi-Square Distribution; D019561:Echocardiography, Four-Dimensional; D005260:Female; D006330:Heart Defects, Congenital / Q000000981:diagnostic imaging*; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D007091:Image Processing, Computer-Assisted; D011247:Pregnancy; D016216:Ultrasonography, Prenatal / Q000379:methods*
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