title: Microwave-assisted synthesis of substituted hexahydro-pyrrolo[3,2-c]quinolines.
abstract: New compounds with the ethyl hexahydro-1H-pyrrolo[3,2-c]quinoline-2-carboxylate skeleton were prepared by microwave-assisted intramolecular 1,3-dipolar cycloaddition reactions. The reactions were carried out under solvent-free conditions and compared with the same reaction in the presence of a solvent and a catalyst. Steric effects on the selectivity of the reaction were noted and evaluated.
authors: Department of Organic Chemistry, Masaryk University, Kotlarska 2, Brno, Czech Republic.
authors: Michal
authors: M
authors: Neuschl
authors: Darek
authors: D
authors: Bogdal
authors: Milan
authors: M
authors: Potacek
mesh_terms: D008872:Microwaves; D008958:Models, Molecular; D015394:Molecular Structure; D011758:Pyrroles / Q000737:chemistry*; D011804:Quinolines / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D011758:Pyrroles; D011804:Quinolines; C037219:quinoline
references: J Org Chem. 2001 Jul 27;66(15):5113-23
references: 11463264