[Prevalence of abnormal glucose regulation in patients with chronic ischemic heart failure].
OBJECTIVE
To investigate the prevalence of diabetes mellitus (DM) and glucose abnormalities in patients with ischemic chronic heart failure (CHF).


METHODS
A total of 1004 hospitalized eligible patients from 52 hospitals in 7 Chinese cities were included in this study.


RESULTS
In this survey, 420 out of 1004 patients had DM history (41.8%), 175 patients were newly diagnosed as DM (17.4%), 208 patients (20.7%) had impaired glucose tolerance (IGT). NYHA grade increases in proportion to severity of abnormal glucose metabolism [(r(s)) = 0.17, P = 0.001]. After adjustment of age and other factors, logistic regression analyses showed risk of suffering severe CHF symptoms (NYHA III/IV) increases with the severity of abnormal glucose metabolism: OR, 1.2, 95% CI: 0.7 - 1.7 in patients with IGT; 1.4, 95% CI: 0.9 - 2.1 in the newly diagnosed DM patients and 1.7, 95% CI: 1.2 - 2.4 in the DM history group, respectively.


CONCLUSIONS
High prevalence of abnormal glucose metabolism was observed in patients with chronic ischemic hear failure and the severity of abnormal glucose metabolism was closely related to NYHA symptom grade.
Liu
Hao
H
Center for Cardiovascular and Pulmonary Blood Vessel, Tongji University, Shanghai, China.
Yu
Jin-Ming
JM
Chen
Fang
F
Pan
Chang-Yu
CY
Li
Jue
J
Hu
Da-Yi
DY
D000368:Aged; D000369:Aged, 80 and over; D001786:Blood Glucose / Q000378:metabolism*; D002681:China; D003327:Coronary Disease / Q000150:complications / Q000453:epidemiology / Q000378:metabolism*; D003920:Diabetes Mellitus / Q000453:epidemiology; D005260:Female; D018149:Glucose Intolerance / Q000453:epidemiology*; D006333:Heart Failure / Q000150:complications / Q000453:epidemiology / Q000378:metabolism*; D006801:Humans; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012307:Risk Factors
D001786:Blood Glucose