title: Deep metazoan phylogeny.
abstract: We reconstructed a robust phylogenetic tree of the Metazoa, consisting of almost 1,500 taxa, by profile neighbor joining (PNJ), an automated computational method that inherits the efficiency of the neighbor joining algorithm. This tree supports the one proposed in the latest review on metazoan phylogeny. Our main goal is not to discuss aspects of the phylogeny itself, but rather to point out that PNJ can be a valuable tool when the basal branching pattern of a large phylogenetic tree must be estimated, whereas traditional methods would be computationally impractical.
authors: Department of Bioinformatics, Biocenter, University of Würzburg, Am Hubland, D-97074 Würzburg, Germany.
authors: Daniel
authors: D
authors: Gerlach
authors: Matthias
authors: M
authors: Wolf
authors: Thomas
authors: T
authors: Dandekar
authors: Tobias
authors: T
authors: Müller
authors: Andreas
authors: A
authors: Pokorny
authors: Sven
authors: S
authors: Rahmann
mesh_terms: D000465:Algorithms; D000818:Animals; D019295:Computational Biology; D008957:Models, Genetic; D010802:Phylogeny; D012337:RNA, Ribosomal, 18S / Q000235:genetics
chemical_list: D012337:RNA, Ribosomal, 18S