The prevalence of atopic triad in children with physician-confirmed atopic dermatitis.
BACKGROUND
Atopic dermatitis (AD) is often associated with comorbidities such as allergic rhinitis and asthma.


OBJECTIVE
We sought to describe the frequency of these comorbidities in children with AD.


METHODS
We conducted a cross-sectional study of the first 2270 children with physician-confirmed AD enrolled in a large postmarketing cohort. All were queried for information on comorbidities using a questionnaire from the International Study of Asthma and Allergies in Childhood.


RESULTS
In all, 71.3% reported at least one additional form of atopy (symptoms of asthma or allergic rhinitis). A total of 33.3% reported only symptoms of asthma or allergic rhinitis whereas 38.0% reported symptoms of asthma and allergic rhinitis. By age 3 years, nearly 66% reported at least one additional form of atopy. A statistically significant trend toward poorer disease control was observed for those with additional atopic illnesses (P < .001).


CONCLUSIONS
This is a cross-sectional study.


CONCLUSIONS
Individuals with AD exhibit a predisposition to additional atopic illnesses by age 3 years and in turn the presence of these illnesses correlates with poor disease control.
Kapoor
Roger
R
George Washington University School of Medicine, Washington, District of Columbia.
Menon
Chandrakala
C
Hoffstad
Ole
O
Bilker
Warren
W
Leclerc
Patricia
P
Margolis
David J
DJ
D000293:Adolescent; D001249:Asthma / Q000453:epidemiology* / Q000503:physiopathology; D002648:Child; D002675:Child, Preschool; D015331:Cohort Studies; D015897:Comorbidity; D003430:Cross-Sectional Studies; D003876:Dermatitis, Atopic / Q000175:diagnosis / Q000453:epidemiology* / Q000503:physiopathology; D005260:Female; D006801:Humans; D006967:Hypersensitivity / Q000150:complications*; D008297:Male; D010820:Physicians; D015995:Prevalence; D012220:Rhinitis / Q000453:epidemiology* / Q000209:etiology* / Q000503:physiopathology