title: Prevalence of serum antibodies against Bartonella species in the serum of cats with or without uveitis.
abstract: Bartonella henselae has been implicated as a causative agent of chronic uveitis in people and in some cats. The objective of this study was to determine whether Bartonella species seroprevalence or titer magnitude varies among cats with uveitis, cats without ocular diseases recorded and healthy cats, while controlling for age and risk of flea exposure based on state of residence. There was no difference in seroprevalence rates or titer magnitude between cats with uveitis and cats with non-ocular diseases. Healthy cats were more likely to be seropositive for Bartonella species than cats with uveitis. The median Bartonella species titer was 1:64 for all groups, although healthy cats were more likely to have higher titers than cats with uveitis and cats with non-ocular disease. The results suggest that serum antibody tests alone cannot be used to document clinical uveitis associated with Bartonella species infection.
authors: Department of Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Veterinary Teaching Hospital, Colorado State University, 300 West Drake Road, Fort Collins, CO 80523, United States.
authors: Jennifer P
authors: JP
authors: Fontenelle
authors: Cynthia C
authors: CC
authors: Powell
authors: Ashley E
authors: AE
authors: Hill
authors: Steven V
authors: SV
authors: Radecki
authors: Michael R
authors: MR
authors: Lappin
mesh_terms: D000818:Animals; D000907:Antibodies, Bacterial / Q000097:blood*; D001474:Bartonella Infections / Q000276:immunology / Q000382:microbiology / Q000662:veterinary*; D018416:Bartonella henselae / Q000276:immunology; D002371:Cat Diseases / Q000453:epidemiology* / Q000276:immunology*; D002415:Cats / Q000276:immunology / Q000382:microbiology; D004269:DNA, Bacterial / Q000032:analysis; D004797:Enzyme-Linked Immunosorbent Assay; D005455:Fluorescent Antibody Technique / Q000662:veterinary; D007124:Immunoenzyme Techniques; D016036:Seroepidemiologic Studies; D014605:Uveitis / Q000276:immunology / Q000382:microbiology / Q000662:veterinary*
chemical_list: D000907:Antibodies, Bacterial; D004269:DNA, Bacterial
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