title: Six-year incidence of visual loss in african americans with type 1 diabetes mellitus: the New Jersey 725.
abstract: OBJECTIVE
  To report the 6-year incidence of visual loss and associated risk factors in African Americans with type 1 diabetes mellitus.
  
  
  METHODS
  African Americans with type 1 diabetes (n=483) who participated in the New Jersey 725 study were reexamined as part of a 6-year follow-up. Best-corrected visual acuity, a structured clinical interview, fundus photographs, and blood pressure measurements were obtained. The biological evaluation included blood and urine assays. Any visual loss was defined as a visual acuity of 20/40 or worse in the better eye, blindness as a visual acuity of 20/200 or worse in the better eye, and doubling of the visual angle (DVA) as the loss of 15 or more letters between the first and second visits.
  
  
  RESULTS
  Over 6 years, 19 of 440 patients (4.3%) developed visual loss in the better eye, 3 of 472 patients (0.6%) became blind, 47 of 481 patients (9.8%) developed DVA in the better eye, and 65 of 481 (13.5%) developed DVA in either eye. Baseline older age, high glycosylated hemoglobin level, retinopathy severity, and proteinuria were characteristics significantly (P<.001 for all) and independently associated with DVA in either eye at follow-up.
  
  
  CONCLUSIONS
  The 6-year incidence of DVA in either eye (13.5%) is high in African Americans with type 1 diabetes. Baseline poor glycemic control, diabetic retinopathy severity, proteinuria, and older age are predictors of visual loss in this population.
authors: The Institute of Ophthalmology and Visual Science, Department of Preventive Medicine & Community Health, University of Medicine & Dentistry of New Jersey, New Jersey Medical School, 90 Bergen St, Room 6164, Newark, NJ 07101-1709, USA. roymo@umdnj.edu
authors: Monique S
authors: MS
authors: Roy
authors: Joan
authors: J
authors: Skurnick
mesh_terms: D000328:Adult; D001741:Black or African American; D000367:Age Factors; D001766:Blindness / Q000150:complications / Q000208:ethnology*; D003922:Diabetes Mellitus, Type 1 / Q000150:complications / Q000208:ethnology*; D018450:Disease Progression; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D008297:Male; D009515:New Jersey / Q000453:epidemiology; D011379:Prognosis; D012307:Risk Factors; D012720:Severity of Illness Index; D012959:Socioeconomic Factors; D013997:Time Factors; D014792:Visual Acuity