Frontal theta EEG activity correlates negatively with the default mode network in resting state.
We used simultaneously recorded EEG and fMRI to investigate in which areas the BOLD signal correlates with frontal theta power changes, while subjects were quietly lying resting in the scanner with their eyes open. To obtain a reliable estimate of frontal theta power we applied ICA on band-pass filtered (2-9 Hz) EEG data. For each subject we selected the component that best matched the mid-frontal scalp topography associated with the frontal theta rhythm. We applied a time-frequency analysis on this component and used the time course of the frequency bin with the highest overall power to form a regressor that modeled spontaneous fluctuations in frontal theta power. No significant positive BOLD correlations with this regressor were observed. Extensive negative correlations were observed in the areas that together form the default mode network. We conclude that frontal theta activity can be seen as an EEG index of default mode network activity.
Scheeringa
René
R
F.C. Donders Centre for Cognitive Neuroimaging, Radboud University Nijmegen, The Netherlands. rene.scheeringa@fcdonders.ru.nl
Bastiaansen
Marcel C M
MC
Petersson
Karl Magnus
KM
Oostenveld
Robert
R
Norris
David G
DG
Hagoort
Peter
P
D000293:Adolescent; D000328:Adult; D001143:Arousal / Q000502:physiology*; D001288:Attention / Q000502:physiology; D001931:Brain Mapping / Q000379:methods*; D002560:Cerebrovascular Circulation; D004569:Electroencephalography; D005260:Female; D005625:Frontal Lobe / Q000098:blood supply / Q000378:metabolism / Q000502:physiology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D010100:Oxygen / Q000097:blood; D025341:Principal Component Analysis; D012146:Rest / Q000502:physiology*; D012815:Signal Processing, Computer-Assisted; D013826:Theta Rhythm
D010100:Oxygen