title: Risk factors for knee osteoarthritis in Morocco. A case control study.
abstract: Osteoarthritis (OA) of the knee is the most common form of arthritis. A positive association between obesity and several occupational factors and knee OA has been observed in previous studies in populations of different ethnicity. The aim of this study was to examine the relation between knee OA and body weight and occupational factors in a Moroccan sample of patients with knee OA. Our cases were consecutive patients diagnosed in our department with knee OA utilizing radiography in a 1-year period. No cases displayed established causes of secondary OA. Controls were selected randomly from the general population and were individually matched to each case for age and sex. Interviews were obtained from 95 cases and controls. Detailed information on general health status, height, weight, smoking habits, specific physical loads from occupation and housework, and sports activities was collected. The risk of knee OA increased with higher body mass index, odds ratio (OR) = 3.12 (95% confidence interval [CI] = 1.67-5.81; p < 0.0001). Sitting more than 3 h/day and climbing stairs more than 50 steps/day were associated with decreased risk of knee OA, OR = 0.29 (95% CI = 0.15-0.56; p = 0.02) and 0.48 (95% CI = 0.26-0.91; p < 0.0001), respectively. Overweight is a risk factor for knee OA, whereas sitting and climbing stairs are inversely associated with knee OA.
authors: Rheumatology and Physical Rehabilitation Department, Military Hospital Mohammed V, PO Box: 1018, Rabat, Morocco.
authors: Aziza
authors: A
authors: Mounach
authors: Abderrazak
authors: A
authors: Nouijai
authors: Imad
authors: I
authors: Ghozlani
authors: Mirieme
authors: M
authors: Ghazi
authors: Lahsen
authors: L
authors: Achemlal
authors: Ahmed
authors: A
authors: Bezza
authors: Abdellah
authors: A
authors: El Maghraoui
mesh_terms: D000328:Adult; D000368:Aged; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009790:Occupations; D016017:Odds Ratio; D020370:Osteoarthritis, Knee / Q000453:epidemiology*; D050177:Overweight / Q000150:complications*; D012307:Risk Factors
references: Ann Rheum Dis. 1957 Dec;16(4):494-502
references: 13498604
references: J Rheumatol. 1995 Mar;22(3):488-93
references: 7783067
references: Curr Opin Rheumatol. 2005 Mar;17 (2):195-200
references: 15711235
references: Arthritis Rheum. 2000 Jul;43(7):1443-9
references: 10902744
references: Ann Intern Med. 1988 Jul 1;109 (1):18-24
references: 3377350
references: J Epidemiol Community Health. 2003 Oct;57(10):823-30
references: 14573590
references: Arthritis Rheum. 2000 May;43(5):995-1000
references: 10817551
references: Am J Epidemiol. 1990 Oct;132(4):701-7
references: 2403110
references: J Rheumatol. 2004 Jan;31(1):157-62
references: 14705235
references: J Am Geriatr Soc. 2000 Sep;48(9):1062-72
references: 10983905
references: Ann Rheum Dis. 1993 Feb;52(2):93-6
references: 8447703
references: Clin Geriatr Med. 1988 May;4(2):241-55
references: 3288318
references: Ann Rheum Dis. 1992 Aug;51(8):932-7
references: 1417116
references: Am J Epidemiol. 2000 Nov 1;152(9):855-62
references: 11085397
references: Ugeskr Laeger. 2006 Jan 9;168(2):187-90
references: 16403348
references: Ann Rheum Dis. 1996 Sep;55(9):668-70
references: 8882146
references: Am J Epidemiol. 1988 Jul;128(1):179-89
references: 3381825
references: Ann Intern Med. 1992 Apr 1;116(7):535-9
references: 1543306
references: Arthritis Rheum. 1988 Mar;31(3):315-24
references: 3358796
references: Eur J Epidemiol. 2005;20(6):537-42
references: 16121763
references: Ann Rheum Dis. 1958 Dec;17(4):388-97
references: 13606727
references: J Rheumatol. 1996 Jul;23(7):1221-6
references: 8823696
references: J Rheumatol. 1988 Dec;15(12):1827-32
references: 3230569
references: Ann Rheum Dis. 1994 Feb;53(2):90-3
references: 8129467
references: Arthritis Rheum. 1989 Feb;32(2):166-72
references: 2920052