Postinfective fatigue syndrome is not associated with altered cytokine production.
Peripheral blood specimens and clinical data were obtained over a 12-month period from subjects in the Dubbo Infection Outcomes Study to examine cytokine production in postinfective fatigue syndrome. Ex vivo production of 8 cytokines was examined in 22 case patients and in 42 control subjects who recovered promptly. No significant differences were found. Ongoing production of the cytokines examined does not play a role in postinfective fatigue syndrome.
Vollmer-Conna
Uté
U
School of Psychiatry, University of New South Wales, Sydney University, Sydney, Australia. ute@unsw.edu.au
Cameron
Barbara
B
Hadzi-Pavlovic
Dusan
D
Singletary
Kristi
K
Davenport
Tracey
T
Vernon
Suzanne
S
Reeves
William C
WC
Hickie
Ian
I
Wakefield
Denis
D
Lloyd
Andrew R
AR
D000293:Adolescent; D000328:Adult; D016207:Cytokines / Q000097:blood*; D015673:Fatigue Syndrome, Chronic / Q000097:blood* / Q000473:pathology; D005260:Female; D006801:Humans; D053583:Interleukin-1beta / Q000097:blood; D015850:Interleukin-6 / Q000097:blood; D008297:Male; D008875:Middle Aged; D014409:Tumor Necrosis Factor-alpha / Q000097:blood
D016207:Cytokines; D053583:Interleukin-1beta; D015850:Interleukin-6; D014409:Tumor Necrosis Factor-alpha