title: Rise of the nanomachine: the evolution of a revolution in medicine.
abstract: Although the current array of nanomachines mostly comprises simple devices (at least from a mechanical viewpoint), the underlying physical and chemical interactions that play key roles in the 'assembly' of these machines have required decades of research to ascertain a fundamental understanding of how such processes can be manipulated at the nanoscale. In this review, we wish to convey a realistic picture of the current developments in the design and implementation of nanomachines, with an emphasis on how these developments are leading to practical applications in medicine, including a sense of how such simple devices are rapidly becoming the building blocks for assembling the nanorobots of tomorrow.
authors: Department of Chemistry, University of Houston, Houston, TX 77204-5003, USA.
authors: Hye Hun
authors: HH
authors: Park
authors: Andrew C
authors: AC
authors: Jamison
authors: T Randall
authors: TR
authors: Lee
mesh_terms: D004867:Equipment Design; D005544:Forecasting; D050997:Nanomedicine / Q000639:trends*; D049329:Nanostructures / Q000737:chemistry* / Q000648:ultrastructure; D012371:Robotics / Q000295:instrumentation* / Q000379:methods / Q000639:trends*; D013673:Technology Assessment, Biomedical; D014159:Transducers; D014481:United States