[Antibiotic prophylaxis not indicated in dental procedures in patients with a joint prosthesis].
Antibiotic prophylaxis is suggested for high-risk patients undergoing dental procedures to prevent haematogenous infection of the artificial joint. However, randomised placebo-controlled trials are lacking. Case reports are difficult to interpret, because bacteraemias are very common after chewing and tooth brushing anyway. Widespread use of antibiotics has serious downsides. Therefore, more convincing data are needed to support the use of antibiotic prophylaxis for high-risk patients.
van der Bruggen
J T
JT
Universitair Medisch Centrum Utrecht, afd. Interne Geneeskunde en In- fectieziekten, Postbus 85.500, 3508 GA Utrecht.
Mudrikova
T
T
D019072:Antibiotic Prophylaxis / Q000009:adverse effects; D016470:Bacteremia / Q000517:prevention & control*; D003362:Cost-Benefit Analysis; D003729:Dental Care / Q000379:methods*; D024881:Drug Resistance, Bacterial; D019317:Evidence-Based Medicine; D006801:Humans; D007595:Joint Prosthesis; D016459:Prosthesis-Related Infections / Q000517:prevention & control*; D012307:Risk Factors