Primary mesenteric venous thrombosis: a study from western India.
BACKGROUND
The prevalence and clinical spectrum of mesenteric venous thrombosis (MVT) in India is largely unknown.


METHODS
We retrospectively re-viewed the case records of patients with primary mesenteric venous thrombosis seen over a 10-year period and retrieved information on clinical picture, underlying hypercoagulable states and outcome.


RESULTS
The 28 cases (mean age 41.2 [SD 10.2] years; 19 male) included 13 with acute MVT, 10 with subacute MVT and 5 with chronic MVT. Ten patients had past thromboembolic events (multiple events in five); four patients had isolated superior mesenteric vein involvement and 14 had multiple vessel involvement. Hypercoagulable state was identified in 17 patients, with multiple etiologies in 7 patients. Pre-operative diagnosis was made in all patients. Ten patients needed surgical management; the rest were managed medically initially, but 2 required surgery on follow up. Seven patients died during a follow up of up to 10 years, with in-hospital mortality during index admission in six.


CONCLUSIONS
Most of the patients with MVT have multiple intra-abdominal vessel involvement and underlying hypercoagulable state. The policy of early treatment with anticoagulation in all and surgical treatment as per need, achieves low mortality.
Amarapurkar
Deepak N
DN
Gastroenterology Department, Bombay Hospital and Medical Research Center, Mumbai, India. amarapurkar@gmail.com
Patel
Nikhil D
ND
Jatania
Jignesh
J
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D007194:India / Q000453:epidemiology; D008297:Male; D008641:Mesenteric Vascular Occlusion / Q000453:epidemiology; D008642:Mesenteric Veins; D008875:Middle Aged; D015995:Prevalence; D012189:Retrospective Studies; D020246:Venous Thrombosis / Q000453:epidemiology