The neurobiology and genetics of impulse control disorders: relationships to drug addictions.
Impulse control disorders (ICDs), including pathological gambling, trichotillomania, kleptomania and others, have been conceptualized to lie along an impulsive-compulsive spectrum. Recent data have suggested that these disorders may be considered addictions. Here, we review the genetic and neuropathological bases of the impulse control disorders and consider the disorders within these non-mutually exclusive frameworks.
Brewer
Judson A
JA
Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.
Potenza
Marc N
MN
D000818:Animals; D003657:Decision Making; D007174:Disruptive, Impulse Control, and Conduct Disorders / Q000209:etiology* / Q000235:genetics; D004298:Dopamine / Q000502:physiology; D004723:Endorphins / Q000502:physiology; D005828:Genetics, Population; D018698:Glutamic Acid / Q000502:physiology; D006801:Humans; D007175:Impulsive Behavior; D017397:Prefrontal Cortex / Q000502:physiology; D012201:Reward; D013315:Stress, Psychological / Q000150:complications; D019966:Substance-Related Disorders / Q000209:etiology* / Q000235:genetics; D005680:gamma-Aminobutyric Acid / Q000502:physiology
D004723:Endorphins; D018698:Glutamic Acid; D005680:gamma-Aminobutyric Acid; D004298:Dopamine
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