Synthesis and antimicrobial activity of novel sulfone-linked bis heterocycles.
Novel sulfone-linked bis heterocycles pyrazolines in combination with thiadiazoles, oxadiazoles and triazoles were prepared from E-styrylsulfonylacetic acid methyl ester and tested for their antimicrobial activity. The compound 8 showed pronounced activity than the compounds 6 and 7.
Padmavathi
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Department of Chemistry, Sri Venkateswara University, Tirupati 517 502, India. vkpuram2001@yahoo.com
Thriveni
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Sudhakar Reddy
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Deepti
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D000900:Anti-Bacterial Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D000935:Antifungal Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D010069:Oxadiazoles / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D011720:Pyrazoles / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D013329:Structure-Activity Relationship; D013450:Sulfones / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D013830:Thiadiazoles / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D014230:Triazoles / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology
D000900:Anti-Bacterial Agents; D000935:Antifungal Agents; D010069:Oxadiazoles; D011720:Pyrazoles; D013450:Sulfones; D013830:Thiadiazoles; D014230:Triazoles