Activation of parieto-frontal stream during reaching and grasping studied by positron emission tomography in monkeys.
The whole brain activation during visually guided reaching and grasping behaviors was investigated in three macaque monkeys using positron emission tomography (PET) scanning with [(15)O]H(2)O. Activation was consistently observed in the parietal regions such as PO, MIP, VIP, LIP and AIP, frontal regions such as PMd, M1 and S1 on the contralateral hemisphere and in the ipsilateral intermediate and lateral deep cerebellar nuclei. Activation was also observed in the areas representing the central and peripheral visual field in the early visual cortices. Thus, the visuo-motor processing, including parieto-frontal stream, involved in the control of visually guided reaching and grasping behaviors could be visualized for the first time in macaque monkeys.
Nishimura
Yukio
Y
Department of Developmental Physiology, National Institute for Physiological Sciences, Myodaiji, Okazaki, Japan.
Onoe
Hirotaka
H
Morichika
Yosuke
Y
Tsukada
Hideo
H
Isa
Tadashi
T
D000818:Animals; D001132:Arm / Q000294:innervation / Q000502:physiology; D001931:Brain Mapping; D002529:Cerebellar Nuclei / Q000033:anatomy & histology / Q000000981:diagnostic imaging / Q000502:physiology; D004292:Dominance, Cerebral / Q000502:physiology; D005260:Female; D005385:Fingers / Q000294:innervation / Q000502:physiology; D005625:Frontal Lobe / Q000033:anatomy & histology / Q000000981:diagnostic imaging / Q000502:physiology*; D018737:Hand Strength / Q000502:physiology*; D008253:Macaca mulatta; D008297:Male; D010101:Oxygen Consumption / Q000502:physiology; D010104:Oxygen Radioisotopes; D010296:Parietal Lobe / Q000033:anatomy & histology / Q000000981:diagnostic imaging / Q000502:physiology*; D049268:Positron-Emission Tomography; D011597:Psychomotor Performance / Q000502:physiology*; D014795:Visual Pathways / Q000033:anatomy & histology / Q000000981:diagnostic imaging / Q000502:physiology*
D010104:Oxygen Radioisotopes