Primary hyperparathyroidism presenting as an exophytic mandibular mass.
A 36-year-old female patient presented with a massive painless swelling in the left mandible. The patient's medical history was unremarkable. The initial clinical and radiological evaluation indicated an aggressive odontogenic neoplasm or a metastasis from an unknown primary; the suspicion of a systemic metabolic or endocrine disorder lay low on the list of differential diagnoses. Further investigations revealed gross skeletal changes and a hypoechoic right parathyroid mass. The total serum parathyroid hormone levels and ultrasound-guided fine needle aspiration cytology (FNAC) of the mandibular and parathyroid lesions provided the diagnosis of primary hyperparathyroidism presenting as a mandibular brown tumour. This case thus highlights the importance of a thorough diagnostic work-up for all lesions in the maxillofacial region and also serves to add another facet to the myriad of presentations associated with primary hyperparathyroidism.
Dinkar
A D
AD
Oral Medicine, Diagnosis and Radiology Department, Goa Dental College and Hospital, Bambolim, Goa 403 202, India.
Sahai
S
S
Sharma
M
M
D000236:Adenoma / Q000175:diagnosis; D000328:Adult; D044963:Biopsy, Fine-Needle; D003937:Diagnosis, Differential; D005260:Female; D006101:Granuloma, Giant Cell / Q000175:diagnosis; D006801:Humans; D049950:Hyperparathyroidism, Primary / Q000175:diagnosis*; D008336:Mandibular Diseases / Q000175:diagnosis*; D010002:Osteitis Fibrosa Cystica / Q000175:diagnosis; D010281:Parathyroid Hormone / Q000097:blood; D010282:Parathyroid Neoplasms / Q000175:diagnosis; D018084:Ultrasonography, Interventional
D010281:Parathyroid Hormone