title: Depressed mood in informal caregivers of individuals with mild cognitive impairment.
abstract: This study estimates the prevalence of depressed mood in caregivers of individuals with mild cognitive impairment (MCI) and assesses whether demographics, stressors, intrapsychic strain, and gain are associated with depressed mood. A secondary analysis of baseline data from the Alzheimer's Disease Cooperative Study MCI trial was conducted using a cross-sectional, correlational design. Descriptive statistics to estimate the prevalence of caregiver depressed mood and univariate and block-wise logistic regression analyses were used. The prevalence of depressed mood in 769 caregivers was 24.6% (95% confidence interval, 21.5-27.7). The odds of being depressed were significantly higher in younger, nonspousal caregivers with less education, who cared for MCI patients with lower activities of daily living functioning, and who perceived greater relational deprivation, higher levels of self-loss, and personal gain. Controlling for relevant variables, relational deprivation and caregiver education continued to be significantly associated with depressed mood. Relational deprivation may be important for future interventions.
authors: Indiana University School of Nursing, Indiana University School of Medicine, Indianapolis, IN 46202, USA. yuelu@iupui.edu
authors: Yueh-Feng Yvonne
authors: YF
authors: Lu
authors: Mary Guerriero
authors: MG
authors: Austrom
authors: Susan M
authors: SM
authors: Perkins
authors: Tamilyn
authors: T
authors: Bakas
authors: Martin R
authors: MR
authors: Farlow
authors: Feng
authors: F
authors: He
authors: Shelia
authors: S
authors: Jin
authors: Anthony
authors: A
authors: Gamst
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000544:Alzheimer Disease; D017028:Caregivers / Q000523:psychology* / Q000706:statistics & numerical data*; D003072:Cognition Disorders; D003430:Cross-Sectional Studies; D003863:Depression / Q000175:diagnosis / Q000453:epidemiology* / Q000523:psychology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D015995:Prevalence; D012720:Severity of Illness Index
references: J Gerontol B Psychol Sci Soc Sci. 1995 Jul;50(4):S194-204
references: 7606535
references: Alzheimer Dis Assoc Disord. 2005 Jul-Sep;19(3):166-9
references: 16118536
references: Gerontologist. 1997 Apr;37(2):218-32
references: 9127978
references: Neurology. 2000 Jun 13;54(11):2072-7
references: 10851365
references: N Engl J Med. 2003 Nov 13;349(20):1891-2
references: 14614164
references: Gerontologist. 2006 Dec;46(6):791-800
references: 17169934
references: Alzheimers Dement. 2006 Jul;2(3):220-33
references: 19595891
references: Neurology. 2004 Apr 13;62(7):1199-201
references: 15079026
references: Alzheimer Dis Assoc Disord. 2003 Jul-Sep;17 Suppl 4:S99-104
references: 14512815
references: Alzheimer Dis Assoc Disord. 2000 Oct-Dec;14(4):187-95
references: 11186595
references: N Engl J Med. 2005 Jun 9;352(23):2379-88
references: 15829527
references: Int Psychogeriatr. 2006 Mar;18(1):151-62
references: 16403246
references: Lancet. 2006 Apr 15;367(9518):1262-70
references: 16631882
references: Gerontologist. 2002 Jun;42(3):356-72
references: 12040138
references: Alzheimer Dis Assoc Disord. 1997;11 Suppl 2:S33-9
references: 9236950
references: Arch Neurol. 1999 Mar;56(3):303-8
references: 10190820
references: Alzheimers Care Q. 2003 Oct 1;4(4):312-330
references: 19997523
references: Gerontologist. 2000 Aug;40(4):437-48
references: 10961033
references: Br J Clin Psychol. 2004 Jun;43(Pt 2):177-196
references: 15169617
references: J Clin Psychol. 2004 Jun;60(6):677-87
references: 15141399
references: Psychol Aging. 2003 Jun;18(2):171-80
references: 12825767
references: West J Nurs Res. 2001 Feb;23(1):33-55
references: 11216023
references: Dement Geriatr Cogn Disord. 2004;17(3):181-7
references: 14739542
references: Neurology. 2002 Mar 12;58(5):758-64
references: 11889240
references: Gerontologist. 1998 Apr;38(2):224-30
references: 9573667
references: J Gerontol. 1991 Nov;46(6):M210-5
references: 1834726
references: JAMA. 2002 Sep 25;288(12):1475-83
references: 12243634
references: Am J Public Health. 1994 Aug;84(8):1261-4
references: 8059882
references: Int J Geriatr Psychiatry. 2005 Jun;20(6):512-22
references: 15920711
references: JAMA. 1995 Apr 26;273(16):1274-8
references: 7646655
references: J Public Health Policy. 2001;22(1):88-97
references: 11382092
references: Arch Psychiatr Nurs. 2003 Jun;17(3):135-43
references: 12840806
references: J Gen Intern Med. 2003 Dec;18(12):1006-14
references: 14687259
references: Gerontologist. 1989 Aug;29(4):449-56
references: 2521102
references: Gerontologist. 2002 Oct;42(5):589-602
references: 12351794
references: Arch Neurol. 2004 Aug;61(8):1290-3
references: 15313849
references: Neurology. 2001 Nov 13;57(9):1655-62
references: 11706107
references: JAMA. 2004 Aug 25;292(8):961-7
references: 15328328
references: Int J Geriatr Psychiatry. 2002 Feb;17(2):184-8
references: 11813283
references: Am J Psychiatry. 1984 Nov;141(11):1356-64
references: 6496779
references: J Aging Health. 1997 May;9(2):222-43
references: 10182405
references: Res Nurs Health. 2003 Oct;26(5):366-75
references: 14579257
references: J Gerontol B Psychol Sci Soc Sci. 2001 Sep;56(5):P301-13
references: 11522805
references: J Am Geriatr Soc. 1999 Feb;47(2):196-202
references: 9988291
references: Am J Alzheimers Dis Other Demen. 2006 Aug-Sep;21(4):242-8
references: 16948288
references: Gerontologist. 2001 Aug;41(4):462-73
references: 11490044
references: Psychol Aging. 2003 Sep;18(3):361-74
references: 14518800
references: Gerontologist. 1995 Dec;35(6):771-91
references: 8557205
references: Br J Psychiatry. 1999 Apr;174:307-11
references: 10533549
references: Gerontologist. 1990 Oct;30(5):583-94
references: 2276631
references: Qual Life Res. 2003;12 Suppl 1:33-41
references: 12803309
references: Int J Geriatr Psychiatry. 2001 Nov;16(11):1092-7
references: 11746656
references: Neurology. 2002 Nov 26;59(10):1594-9
references: 12451203
references: J Neurol. 2003 Aug;250(8):907-12
references: 12928907