title: Automated MR spectroscopy of intra- and extraventricular neurocytomas.
abstract: OBJECTIVE
  We evaluated the automated magnetic resonance spectroscopic (MRS) characteristics of intra- and extraventricular neurocytomas.
  
  
  METHODS
  One extra- and 4 intraventricular neurocytomas were studied. Automated single-voxel proton MRS was performed with a 1.5 T MR scanner. The results of 6 total automated MR spectra were analyzed for each tumor.
  
  
  RESULTS
  Lactate resonance was detected as a doublet in 3 MR spectra of 2 intraventricular neurocytomas. A peak corresponding to N-acetylaspartate (NAA) was small in 5 MR spectra of 4 intraventricular neurocytomas. Creatine (Cr) resonance was detected in all 6 MR spectra. Prominent choline (Cho) resonance was found in all 6 MR spectra. The myoinositol (MI) and/or glycine (Gly) peaks were large in 3 MR spectra of 2 intraventricular neurocytomas.
  
  
  CONCLUSIONS
  The presence of the NAA signal and high MI and/or Gly signals may be characteristic features of intraventricular neurocytomas. A combination of prominent Cho resonance and detectable Cr resonance is a common feature of both intra- and extraventricular neurocytomas.
authors: Department of Radiology, Kanazawa University School of Medicine, Kanazawa, Japan. fumiaki@xd6.so-net.ne.jp
authors: Fumiaki
authors: F
authors: Ueda
authors: Masayuki
authors: M
authors: Suzuki
authors: Osamu
authors: O
authors: Matsui
authors: Naoyuki
authors: N
authors: Uchiyama
mesh_terms: D000293:Adolescent; D000328:Adult; D001224:Aspartic Acid / Q000031:analogs & derivatives / Q000378:metabolism; D001921:Brain / Q000473:pathology; D002551:Cerebral Ventricle Neoplasms / Q000175:diagnosis* / Q000378:metabolism; D002552:Cerebral Ventricles / Q000473:pathology*; D002794:Choline / Q000378:metabolism; D003287:Contrast Media / Q000008:administration & dosage; D003401:Creatine / Q000378:metabolism; D005260:Female; D019786:Gadolinium DTPA; D005998:Glycine / Q000378:metabolism; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D007091:Image Processing, Computer-Assisted / Q000379:methods; D007294:Inositol / Q000378:metabolism; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D008297:Male; D018306:Neurocytoma / Q000175:diagnosis* / Q000378:metabolism; D015203:Reproducibility of Results
chemical_list: D003287:Contrast Media; D001224:Aspartic Acid; D007294:Inositol; C000179:N-acetylaspartate; D019786:Gadolinium DTPA; D003401:Creatine; D002794:Choline; D005998:Glycine