Ethylenevinylalcohol copolymer (Onyx-18) used in endovascular treatment of vein of Galen malformation.
BACKGROUND
Vein of Galen malformations (VGM) are rare congenital arteriovenous fistulas that usually present with heart failure in the neonate. Endovascular treatment options in the past have utilized coils, balloons, and acrylics.


METHODS
We present, for the first time in the literature, a case of an infant with VGM treated initially with staged coil embolizations followed 1 year later by the transarterial and transvenous catheter based injection of Onyx-18 (ethylenevinylalcohol copolymer) in a single treatment session. The fistula was eliminated, and the infant's cardiopulmonary symptoms were improved.
Germanwala
Anand V
AV
Department of Neurological Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA.
Vora
Nirav A
NA
Thomas
Ajith J
AJ
Jovin
Tudor
T
Gologorsky
Yakov
Y
Horowitz
Michael B
MB
D004621:Embolization, Therapeutic / Q000379:methods*; D006333:Heart Failure / Q000209:etiology / Q000628:therapy*; D006801:Humans; D007231:Infant, Newborn; D007269:Injections, Intra-Arterial; D007275:Injections, Intravenous; D008297:Male; D011145:Polyvinyls / Q000008:administration & dosage / Q000627:therapeutic use*; D016896:Treatment Outcome; D054080:Vein of Galen Malformations / Q000150:complications / Q000175:diagnosis / Q000628:therapy*
D011145:Polyvinyls; C020320:ethylene-vinyl alcohol copolymer
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