Endometrial carcinosarcoma presenting as a tibial metastasis.
Metastasis to a lower-extremity bone is an extremely rare event in patients with endometrial carcinoma. A 64-year-old woman presented with progressive right leg pain but no gynecologic complaints. A diagnostic workup revealed primary endometrial carcinosarcoma with an isolated tibial metastasis. Though the patient received only local irradiation to the tibial lesion, complete resolution of symptoms resulted. Six months after the radiotherapy, the intraabdominal disease progressed and the patient died. We note that tibial metastasis is one of the possible presenting symptoms in patients with endometrial malignant tumors. Irradiation can improve their quality of life and so may be effective in the management of symptomatic tibial metastasis.
Ishibashi
Masako
M
Department of Obstetrics and Gynecology, Matsue Red Cross Hospital, Horo 200, Matsue, 690-8506, Japan.
Fujiwaki
Ritsuto
R
Nakayama
Ichiro
I
Miura
Hiroshi
H
Sawada
Kohji
K
D001859:Bone Neoplasms / Q000473:pathology / Q000532:radiotherapy / Q000556:secondary*; D002296:Carcinosarcoma / Q000473:pathology / Q000532:radiotherapy / Q000556:secondary*; D016889:Endometrial Neoplasms / Q000473:pathology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D011859:Radiography; D013977:Tibia / Q000000981:diagnostic imaging / Q000473:pathology*
Cancer. 1989 Mar 1;63(5):935-8
2914299
Eur J Gynaecol Oncol. 1997;18(2):144-5
9105868
Injury. 1983 May;14(6):541-5
6874063
Gynecol Oncol. 1990 Nov;39(2):108-14
2227582
CA Cancer J Clin. 2004 Mar-Apr;54(2):94-109
15061599
Gynecol Oncol. 2001 Jul;82(1):216-8
11426991
Obstet Gynecol. 2002 Nov;100(5 Pt 2):1067-9
12423807
Int J Gynecol Pathol. 1988;7(4):361-72
2466009
Skeletal Radiol. 1987;16(5):387-92
3306939
Obstet Gynecol. 1970 May;35(5):769-80
4315044