title: Senescence in the worker honey bee Apis Mellifera.
abstract: Honey bees are social insects that exhibit striking caste-specific differences in longevity. Queen honey bees live on average 1-2 years, whereas workers live 2-6 weeks in the summer and about 20 weeks in the winter. It is not clear whether queen-worker differences in longevity are due to intrinsic physiological differences in the rate of senescence, to differential exposure to extrinsic factors such as predation and adverse environmental conditions, or both. To determine if the relatively short lifespan of worker bees involves senescence, we measured age-specific resistance to three different physiological stressors (starvation, thermal, and oxidative stress) while eliminating age-related differences in foraging activity and minimizing age-related differences in energy expenditure. Despite these manipulations, older worker bees were still significantly less resistant to all three stressors than were younger bees. These results indicate that the regulation of worker bee lifespan involves senescence, in addition to extrinsic factors.
authors: Department of Animal Biology, 515 Morrill Hall, University of Illinois, Urbana, IL 61801, USA. remolina@uiuc.edu
authors: Silvia C
authors: SC
authors: Remolina
authors: Daniel M
authors: DM
authors: Hafez
authors: Gene E
authors: GE
authors: Robinson
authors: Kimberly A
authors: KA
authors: Hughes
mesh_terms: D000375:Aging / Q000502:physiology*; D000818:Animals; D001516:Bees / Q000378:metabolism / Q000502:physiology*; D015331:Cohort Studies; D005260:Female; D050356:Lipid Metabolism; D018384:Oxidative Stress
references: Exp Gerontol. 1999 Aug;34(5):621-31
references: 10530788
references: Nature. 2000 Nov 9;408(6809):233-8
references: 11089980
references: Exp Gerontol. 2000 Oct;35(8):957-69
references: 11121683
references: Exp Gerontol. 2001 Apr;36(4-6):695-711
references: 11295509
references: Proc Natl Acad Sci U S A. 2004 Mar 9;101(10):3486-9
references: 14993600
references: Exp Gerontol. 2004 May;39(5):767-73
references: 15130671
references: Annu Rev Entomol. 1992;37:637-65
references: 1539941
references: Aging Cell. 2005 Feb;4(1):13-9
references: 15659209
references: Mech Ageing Dev. 2005 Nov;126(11):1230-8
references: 16139867
references: Exp Gerontol. 2005 Dec;40(12):939-47
references: 16169181
references: J Exp Biol. 2005 Dec;208(Pt 24):4641-9
references: 16326945
references: Proc Natl Acad Sci U S A. 2006 Jan 24;103(4):962-7
references: 16418279
references: Mech Ageing Dev. 2006 Jul;127(7):647-51
references: 16616306
references: Exp Gerontol. 2006 Sep;41(9):877-81
references: 16891076
references: Curr Biol. 2007 Apr 17;17(8):R274-5
references: 17437701
references: Proc Natl Acad Sci U S A. 2007 Apr 24;104(17):7128-33
references: 17438290
references: Science. 1989 Oct 6;246(4926):109-12
references: 17837770
references: Evolution. 1984 Sep;38(5):996-1003
references: 28555795
references: Evolution. 1984 Sep;38(5):1004-1010
references: 28555803
references: Genetica. 1993;91(1-3):89-98
references: 8125281
references: Science. 1996 Jul 5;273(5271):80
references: 8658201
references: Mol Cell Biol. 1999 Jan;19(1):216-28
references: 9858546