Fatal right-sided endocarditis due to Aspergillus in a kidney transplant recipient.
Invasive aspergillosis (IA) is an emerging infectious disease in different groups of immunocompromised patients. In transplant recipients, intensification of immunosuppressive therapy to treat allograft rejection poses a major risk factor for IA. We present the clinical features, diagnostic findings and outcome of a kidney transplant recipient who developed pulmonary aspergillosis complicated by endocarditis of his native tricuspid valve. Despite replacement of the valve and treatment with combined antifungal therapy, the patient died of an acute pulmonary bleeding.
Van Meensel
Britt
B
Department of Laboratory Medicine, UZ Gasthuisberg, Leuven, Belgium. britt.vanmeensel@gmail.com
Meersseman
Wouter
W
Bammens
Bert
B
Peetermans
Willy E
WE
Herregods
Marie-Christine
MC
Herijgers
Paul
P
Lagrou
Katrien
K
D001228:Aspergillosis / Q000150:complications* / Q000382:microbiology; D001232:Aspergillus fumigatus / Q000145:classification / Q000302:isolation & purification*; D004696:Endocarditis / Q000382:microbiology*; D017809:Fatal Outcome; D006349:Heart Valve Diseases / Q000382:microbiology; D006801:Humans; D016030:Kidney Transplantation / Q000009:adverse effects*; D008172:Lung Diseases, Fungal / Q000150:complications* / Q000382:microbiology; D008297:Male; D008875:Middle Aged; D014261:Tricuspid Valve / Q000382:microbiology*