title: Serological evidence of possible human infection with Tioman virus, a newly described paramyxovirus of bat origin.
abstract: Tioman virus, a relatively new paramyxovirus, was isolated from fruit bats (Pteropus species) on Tioman Island, Malaysia, in 2001. The objective of this study was to determine the prevalence of antibodies to T. virus in island inhabitants, by use of comparative ELISA and serum neutralization assays. Of the 169 human sera analyzed, 5 (approximately 3.0%) were positive for T. virus, by comparative ELISA. Of these 5 sera, 3 (1.8% of the total) had neutralizing antibodies against T. virus, suggesting previous infection of this study population by this virus or a similar virus.
authors: Department of Pathology, University of Malaya, Kuala Lumpur, Malaysia.
authors: Koon Chu
authors: KC
authors: Yaiw
authors: Gary
authors: G
authors: Crameri
authors: Linfa
authors: L
authors: Wang
authors: Heng Thay
authors: HT
authors: Chong
authors: Kaw Bing
authors: KB
authors: Chua
authors: Chong Tin
authors: CT
authors: Tan
authors: Khean Jin
authors: KJ
authors: Goh
authors: Devi
authors: D
authors: Shamala
authors: K Thong
authors: KT
authors: Wong
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000818:Animals; D000914:Antibodies, Viral / Q000097:blood*; D002685:Chiroptera / Q000821:virology*; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D008296:Malaysia / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D009500:Neutralization Tests; D018184:Paramyxoviridae Infections / Q000453:epidemiology* / Q000276:immunology / Q000635:transmission / Q000662:veterinary; D018098:Paramyxovirinae / Q000276:immunology*; D016036:Seroepidemiologic Studies; D015047:Zoonoses
chemical_list: D000914:Antibodies, Viral