title: Synovial sarcoma of the sellar region.
abstract: Primary sarcomas of the sellar region are uncommon, although a wide variety have been reported. To date, no cases of primary synovial sarcoma have been described as occurring at this site. We report an immunohistochemically and molecular genetically confirmed primary synovial sarcoma involving the sellar/parasellar region and cavernous sinus in an adult male. Subtotal resection and radiosurgery proved to be efficacious. The spectrum of primary sellar region sarcomas is summarized.
authors: Department of Laboratory Medicine and Pathology, Mayo Clinic, 200 First St., SW, Rochester, MN 55905, USA. scheithauer.bernd@mayo.edu
authors: Bernd W
authors: BW
authors: Scheithauer
authors: Ana Isabel
authors: AI
authors: Silva
authors: Keith
authors: K
authors: Kattner
authors: Jason
authors: J
authors: Seibly
authors: Andre M
authors: AM
authors: Oliveira
authors: Kalman
authors: K
authors: Kovacs
mesh_terms: D002426:Cavernous Sinus / Q000473:pathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000473:pathology; D019635:Neurosurgical Procedures; D015514:Oncogene Proteins, Fusion; D016634:Radiosurgery; D020133:Reverse Transcriptase Polymerase Chain Reaction; D013584:Sarcoma, Synovial / Q000235:genetics / Q000473:pathology* / Q000628:therapy*; D012658:Sella Turcica / Q000473:pathology*; D019292:Skull Base Neoplasms / Q000235:genetics / Q000473:pathology* / Q000628:therapy*; D014178:Translocation, Genetic
chemical_list: D015514:Oncogene Proteins, Fusion; C116512:SYT-SSX fusion protein
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