Antibacterial prophylaxis in neutropenic patients.
Antibiotic prophylaxis has been used for several decades to prevent infection in chemotherapy-induced neutropenia and its benefits have been debated just as long. Recent analysis suggests that quinolones may actually be life saving in high-risk groups such as acute leukaemia and autologous bone marrow transplant but these benefits are likely to be negated in the long term by the development of quinolone resistance.
Viscoli
Claudio
C
Division of Infectious Disease, University of Genova and San Martino University Hospital, Genova, Italy. viscoli@unige.it
D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D019072:Antibiotic Prophylaxis; D001424:Bacterial Infections / Q000517:prevention & control*; D002648:Child; D006801:Humans; D009503:Neutropenia / Q000150:complications*; D015363:Quinolones / Q000627:therapeutic use
D000900:Anti-Bacterial Agents; D015363:Quinolones