title: [Closed-loop titration of propofol guided by the bispectral index].
abstract: This review analyzes the clinical studies concerning the automated perfusion, or closed-loop, of propofol guided by the bispectral index (BIS). To carry out the maintenance of general anaesthesia by a closed loop propofol-BIS is feasible as shown by studies comprising few low risk patients. We showed that induction of anaesthesia is feasible with a closed loop, haemodynamic stability being similar to a manual titration. A second study, bearing on the whole of the anaesthesia of patients ASA I to III undergoing very diverse surgical acts, showed that the closed loop propofol-BIS was more precise than a manual perfusion. This confirms that the closed loop propofol-BIS is not an esoteric research and that it represents a tool with a future for the clinician.
authors: Service d'anesthésie, hôpital Foch, 40, rue Worth, 92151 Suresnes, France.
authors: N
authors: N
authors: Liu
authors: T
authors: T
authors: Chazot
authors: B
authors: B
authors: Trillat
authors: G A
authors: GA
authors: Dumont
authors: M
authors: M
authors: Fischler
mesh_terms: D000465:Algorithms; D018686:Anesthetics, Intravenous / Q000008:administration & dosage / Q000494:pharmacology*; D001794:Blood Pressure / Q000187:drug effects; D016503:Drug Delivery Systems / Q000379:methods; D006801:Humans; D016343:Monitoring, Intraoperative / Q000379:methods*; D015742:Propofol / Q000008:administration & dosage / Q000494:pharmacology*; D013514:Surgical Procedures, Operative / Q000145:classification
chemical_list: D018686:Anesthetics, Intravenous; D015742:Propofol