title: Amplitude modulation patterns of local field potentials reveal asynchronous neuronal populations.
abstract: Neural oscillations, which appear in several areas of the nervous system and cover a wide frequency range, are a prominent issue in current neuroscience. Extracellularly recorded oscillations are generally thought to be a manifestation of a neural population with synchronized electrical activity resulting from coupling mechanisms. The vertebrate olfactory neuroepithelium exhibits beta-band oscillations, termed peripheral waves (PWs), in their population response to odor stimulation. Here, we examine PWs in the channel catfish and propose that their properties could be explained as the superposition of asynchronous oscillators. Our model shows that the intriguing random pattern of amplitude-modulated PWs could be explained by Rayleigh fading, an interference phenomenon well known in physics and recognizable using statistical methods and signal analysis. We are proposing a mathematical fingerprint to characterize neural signals generated by the addition of random phase oscillators. Our interpretation of PWs as arising from asynchronous oscillators could be generalized to other neuronal populations, because it suggests that neural oscillations, detected in local field potential recordings within a narrow frequency band, do not necessarily originate from synchronization events.
authors: Department of Biology, Faculty of Sciences, University of Chile, Santiago, Chile 7800023.
authors: Javier
authors: J
authors: Díaz
authors: Pablo
authors: P
authors: Razeto-Barry
authors: Juan-Carlos
authors: JC
authors: Letelier
authors: John
authors: J
authors: Caprio
authors: Juan
authors: J
authors: Bacigalupo
mesh_terms: D000818:Animals; D001683:Biological Clocks / Q000502:physiology*; D004558:Electric Stimulation / Q000379:methods; D007059:Ictaluridae / Q000033:anatomy & histology; D008433:Mathematics; D008564:Membrane Potentials / Q000187:drug effects / Q000502:physiology*; D008954:Models, Biological; D009474:Neurons / Q000502:physiology*; D009812:Odorants; D009830:Olfactory Bulb / Q000166:cytology; D018408:Patch-Clamp Techniques
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