Fetal nutrition and adult hypertension, diabetes, obesity, and coronary artery disease.
The fetal-origins-of-adult-disease hypothesis describes an adaptive phenomenon of in utero reprogramming of the undernourished fetus that predisposes the infant to increased morbidity as an adult. Studies have identified a positive association between indicators of fetal undernutrition such as low birth weight and chronic adult diseases like hypertension, diabetes, obesity, and coronary artery disease. Current research is focusing on determining other factors that may contribute to these chronic adult diseases.
Thompson
Joan Nalani
JN
University of Hawaii at Hilo, USA. jniaukea@hawaii.edu
D000328:Adult; D017668:Age of Onset; D000818:Animals; D001724:Birth Weight; D015984:Causality; D002908:Chronic Disease; D003324:Coronary Artery Disease / Q000453:epidemiology / Q000209:etiology*; D003920:Diabetes Mellitus / Q000453:epidemiology / Q000209:etiology*; D004195:Disease Models, Animal; D048070:Fetal Nutrition Disorders / Q000175:diagnosis / Q000453:epidemiology* / Q000517:prevention & control; D006801:Humans; D007227:Infant Nutritional Physiological Phenomena; D007231:Infant, Newborn; D009017:Morbidity; D015596:Nutrition Assessment; D009749:Nutrition Surveys; D009752:Nutritional Status; D009765:Obesity / Q000453:epidemiology / Q000209:etiology*; D015430:Weight Gain