Con-Struct Map: a comparative contact map analysis tool.
Con-Struct Map is a graphical tool for the comparative study of protein structures. The tool detects potential conserved residue contacts shared by multiple protein structures by superimposing their contact maps according to a multiple structure alignment. In general, Con-Struct Map allows the study of structural changes resulting from, e.g. sequence substitutions, or alternatively, the study of conserved components of a structure framework across structurally aligned proteins. Specific applications include the study of sequence-structure relationship in distantly related proteins and the comparisons of wild type and mutant proteins.


BACKGROUND
http://pdbrs3.sdsc.edu/ConStructMap/viewer_argument_generator/singleArguments.


BACKGROUND
Supplementary data are available at Bioinformatics online.
Chung
Jo-Lan
JL
Department of Chemistry and Biochemistry, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA.
Beaver
John E
JE
Scheeff
Eric D
ED
Bourne
Philip E
PE
D000465:Algorithms; D000595:Amino Acid Sequence; D001665:Binding Sites; D003196:Computer Graphics; D003198:Computer Simulation; D008956:Models, Chemical; D008958:Models, Molecular; D008969:Molecular Sequence Data; D011485:Protein Binding; D025941:Protein Interaction Mapping / Q000379:methods*; D011506:Proteins / Q000737:chemistry* / Q000648:ultrastructure*; D016415:Sequence Alignment / Q000379:methods*; D020539:Sequence Analysis, Protein / Q000379:methods; D012984:Software; D014584:User-Computer Interface
D011506:Proteins