Adverse reaction to Bacille-Calmette-Guérin vaccine in a HIV positive healthcare worker.
BACKGROUND
The Bacille-Calmette-Guérin (BCG) vaccine is used in Mycobacterium tuberculosis prophylaxis in at risk tuberculin-negative healthcare workers. Its use is contraindicated however in individuals with HIV infection.


OBJECTIVE
We herein highlight the case of a healthcare worker who developed a localised reaction at a BCG vaccination site and who was subsequently found to be HIV positive.


CONCLUSIONS
This case emphasises the importance of eliciting risk factors for immunocompromise in individuals for whom BCG vaccination is being considered.
Garvey
J F
JF
Department of Respiratory Medicine, St. Vincent's University Hospital, Elm Park, Dublin 4, Ireland. john.garvey@ucd.ie
Gueret
P
P
McDonnell
T J
TJ
D000328:Adult; D000488:Allied Health Personnel; D000904:Antibiotics, Antitubercular / Q000627:therapeutic use; D001500:BCG Vaccine / Q000009:adverse effects* / Q000276:immunology; D000075202:Contraindications; D006679:HIV Seropositivity / Q000276:immunology; D006801:Humans; D008297:Male; D009163:Mycobacterium bovis / Q000302:isolation & purification; D012293:Rifampin / Q000627:therapeutic use; D012883:Skin Ulcer / Q000209:etiology*; D014376:Tuberculosis / Q000517:prevention & control
D000904:Antibiotics, Antitubercular; D001500:BCG Vaccine; D012293:Rifampin
Ann Intern Med. 1994 Jan 1;120(1):71-9
8250459
Clin Diagn Lab Immunol. 2005 Nov;12(11):1298-304
16275944
Clin Infect Dis. 2000 Sep;31 Suppl 3:S75-6
11010827
Am J Respir Crit Care Med. 1995 Jan;151(1):129-35
7812542
JAMA. 1994 Mar 2;271(9):698-702
8309034