Fluoroscopic-guided intradiscal oxygen-ozone injection therapy for thoracolumbar intervertebral disc herniations in dogs.
BACKGROUND
To investigate the effect of oxygen-ozone (O2-O3) injection on thoracolumbar intervertebral disc herniation (IVDH) in dogs.


METHODS
Ten herniated discs of five dogs were treated with percutaneous injection of an O2-O3 gas mixture with O3 concentration of 32 microg/microl intradiscally (1.5-2 microl) under fluoroscopy guidance.


RESULTS
Five weeks after treatment, the mean size of herniated discs was measured by computed tomography and showed significant reduction of disc volumes in all animals (8.8%+/-3.82%). The degree of shrinkage was negatively linearly correlated with disc mineralization (correlation coefficient=-0.636) and statistically significant at p<0.05. All five dogs regained their gait function and none recurred.


CONCLUSIONS
We conclude that intradiscal O2-O3 injection can decompress affected discs by disc shrinkage.
Han
Hyun-Jung
HJ
Department of Veterinary Surgery, College of Veterinary Medicine, Chungbuk National University, Chungbuk, 361-763, Republic of Korea.
Kim
Joon-Young
JY
Jang
Ha-Young
HY
Lee
Bora
B
Yoon
Jung-Hee
JH
Jang
Sang-Keun
SK
Choi
Seok Hwa
SH
Jeong
Soon-Wuk
SW
D000818:Animals; D002114:Calcinosis / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000662:veterinary; D004285:Dogs; D005471:Fluoroscopy; D005500:Follow-Up Studies; D015552:Injections, Intralesional; D007405:Intervertebral Disc Displacement / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000662:veterinary*; D008159:Lumbar Vertebrae; D010100:Oxygen / Q000008:administration & dosage*; D010126:Ozone / Q000008:administration & dosage*; D013904:Thoracic Vertebrae; D016896:Treatment Outcome
D010126:Ozone; D010100:Oxygen