Subglottic MALT lymphoma of the larynx--more attention to the glottis.
BACKGROUND
Mucosa-associated lymphoid tissue (MALT) lymphoma of the larynx is a rare but well-documented entity which may arise from chronic inflammatory process. Supraglottic left regions are predominant due to unknown reason.


METHODS
We present the case of a 62-year-old man with a dry cough, stridor and developing exertional dyspnea. This subglottic almost circumferential MALT lymphoma showed a temporary distinct disappearance after cortisone administration during the diagnostic process. Bronchoscopy confirmed the diagnosis of a primary MALT lymphoma of the larynx. The patient received chemotherapy according to CHOP scheme plus rituximab. A reliable post-treatment care period of 15 months showed no sign of recurrence.


CONCLUSIONS
MALT lymphoma of the larynx are believed to arise from preexisting or acquired lymphoid tissue of the upper airway. Acquired lymphoid tissue is documented in the supraglottic region and may be associated with a chronic inflammatory process. However, in subglottic cases it is unclear whether the chronic inflammation arises from a local or systemic process.
Steffen
Armin
A
Department of Otorhinolaryngology, University of Luebeck, RatzeburgerAllee 160, 23538 Luebeck, Germany. armin.steffen@hno.uni-luebeck.de
Jafari
Claudia
C
Merz
Hartmut
H
Galle
Jurgen
J
Berger
Gabriele
G
D000893:Anti-Inflammatory Agents / Q000008:administration & dosage; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage; D001999:Bronchoscopy; D003348:Cortisone / Q000008:administration & dosage; D004417:Dyspnea / Q000276:immunology / Q000473:pathology; D005931:Glottis / Q000000981:diagnostic imaging / Q000473:pathology*; D006801:Humans; D007249:Inflammation / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000473:pathology; D007822:Laryngeal Neoplasms / Q000188:drug therapy / Q000276:immunology* / Q000473:pathology*; D018442:Lymphoma, B-Cell, Marginal Zone / Q000188:drug therapy / Q000276:immunology* / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D012135:Respiratory Sounds / Q000276:immunology; D014057:Tomography, X-Ray Computed
D000893:Anti-Inflammatory Agents; D003348:Cortisone