title: "Cassette" in situ enzymatic screening identifies complementary chiral scaffolds for hydrolytic kinetic resolution across a range of epoxides.
authors: Department of Chemistry, University of Nebraska, Lincoln, NE 68588, USA.
authors: Sangeeta
authors: S
authors: Dey
authors: Douglas R
authors: DR
authors: Powell
authors: Chunhua
authors: C
authors: Hu
authors: David B
authors: DB
authors: Berkowitz
mesh_terms: D000085:Acetates / Q000737:chemistry; D001681:Biological Assay; D003035:Cobalt / Q000737:chemistry; D020650:Combinatorial Chemistry Techniques; D004798:Enzymes / Q000737:chemistry / Q000378:metabolism*; D004852:Epoxy Compounds / Q000737:chemistry*; D008968:Molecular Conformation; D015394:Molecular Structure
chemical_list: D000085:Acetates; D004798:Enzymes; D004852:Epoxy Compounds; D003035:Cobalt
references: Angew Chem Int Ed Engl. 2005 Mar 4;44(11):1690-3
references: 15688352
references: Angew Chem Int Ed Engl. 2002 May 3;41(9):1603-7
references: 19750680
references: Chem Soc Rev. 2006 May;35(5):416-23
references: 16636725
references: Mol Biosyst. 2005 Oct;1(4):303-6
references: 16880995
references: J Am Chem Soc. 2002 Aug 7;124(31):9020-1
references: 12148984
references: Angew Chem Int Ed Engl. 2003 Dec 15;42(48):5984-7
references: 14679549
references: Curr Opin Chem Biol. 2003 Jun;7(3):420-6
references: 12826131
references: Org Lett. 2005 Oct 27;7(22):5099-102
references: 16235967
references: J Org Chem. 2003 Oct 17;68(21):8136-41
references: 14535795
references: J Org Chem. 2001 Aug 10;66(16):5522-7
references: 11485477
references: J Am Chem Soc. 2003 Jul 16;125(28):8672-9
references: 12848575
references: Org Lett. 2004 Aug 5;6(16):2661-4
references: 15281738
references: Angew Chem Int Ed Engl. 1999 Jun 14;38(12):1758-1761
references: 29711209
references: J Am Chem Soc. 2001 Sep 19;123(37):9206-7
references: 11552847
references: Chem Commun (Camb). 2004 Jun 21;(12):1366-7
references: 15179467
references: Org Lett. 2005 Apr 28;7(9):1837-9
references: 15844919
references: J Am Chem Soc. 2004 Feb 11;126(5):1360-2
references: 14759192
references: Chemistry. 2003 Aug 18;9(16):3882-7
references: 12916113
references: Curr Opin Chem Biol. 2004 Jun;8(3):311-8
references: 15183330
references: J Am Chem Soc. 2006 May 24;128(20):6532-3
references: 16704233
references: J Am Chem Soc. 2001 Jan 17;123(2):361-2
references: 11456535
references: J Am Chem Soc. 2006 Feb 22;128(7):2234-5
references: 16478176
references: Anal Chem. 2004 Feb 15;76(4):1184-8
references: 14961753
references: Chemistry. 2001 Feb 2;7(3):730-7
references: 11261671
references: Chirality. 2002 Jul;14(7):534-40
references: 12112324
references: Angew Chem Int Ed Engl. 2002 Jan 4;41(1):124-7
references: 12491459
references: J Am Chem Soc. 2002 May 1;124(17):4554-5
references: 11971690
references: Nature. 2006 Sep 7;443(7107):67-70
references: 16957727
references: J Am Chem Soc. 2005 Jun 22;127(24):8610-1
references: 15954763
references: Drug Discov Today. 2002 Oct 1;7(19):1002-12
references: 12546918
references: Angew Chem Int Ed Engl. 2004 May 3;43(19):2498-500
references: 15127434
references: Angew Chem Int Ed Engl. 1998 Oct 16;37(19):2647-2650
references: 29711629
references: Tetrahedron Asymmetry. 2004 Sep 20;15(18):2845-2851
references: 30147246
references: Chemistry. 2007;13(1):99-104
references: 17066491
references: J Am Chem Soc. 2002 Feb 20;124(7):1307-15
references: 11841300
references: Angew Chem Int Ed Engl. 2007;46(8):1315-7
references: 17211916