title: Liver abscesses in Holstein dairy cattle: 18 cases (1992-2003).
abstract: BACKGROUND
  The characteristic clinical manifestations, clinicopathologic findings, treatment, and outcome of dairy cattle with liver abscess are poorly defined.
  
  
  METHODS
  The study included 18 Holstein cows with liver abscesses.
  
  
  METHODS
  A retrospective study of medical records was performed. Cattle with liver abscess were identified by ultrasound examination or exploratory laparotomy.
  
  
  RESULTS
  The most common reason for examination was anorexia (14/18). Five cows had fever, 5 were bradycardic, and 5 were tachycardic. Peritonitis (n=6) and vagal indigestion (n=4) were the most frequently associated diseases. Neutrophilia (n=14), hyperfibrinogenemia (n=11), and high serum globulin concentration (n=10) were characteristic of chronic inflammation. Evidence of liver disease on serum biochemistry profile was uncommon. The most common bacterium isolated from the abscess was Arcanobacterium pyogenes (n=4). Anaerobic bacteria were isolated frequently (n=7). There were 6 polymicrobial isolates, with both aerobic and anaerobic bacteria, out of 8 positive samples. Medical treatment was successful in 5 of 7 cattle. Five cows were euthanized and postmortem examination revealed 2 cattle with thrombosis of caudal vena cava.
  
  
  CONCLUSIONS
  Holstein dairy cattle affected by liver abscess exhibit no pathognomonic clinical signs. Clinicopathologic findings were often consistent with a chronic active inflammation. Liver abscesses should be included in the differential diagnosis in cattle with a chronic inflammatory process, cranial peritonitis, or vagal indigestion. Prolonged treatment with antimicrobials might be successful.
authors: Veterinary Medical Teaching Hospital, School of Veterinary Medicine, University of California, Davis, CA 95616, USA. edore@vmth.ucdavis.edu
authors: Elizabeth
authors: E
authors: Doré
authors: Gilles
authors: G
authors: Fecteau
authors: Pierre
authors: P
authors: Hélie
authors: David
authors: D
authors: Francoz
mesh_terms: D000667:Ampicillin / Q000627:therapeutic use; D000818:Animals; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002417:Cattle; D002418:Cattle Diseases / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D003612:Dairying; D005260:Female; D008100:Liver Abscess / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology / Q000662:veterinary*; D010402:Penicillin G Procaine / Q000627:therapeutic use; D012189:Retrospective Studies
chemical_list: D000900:Anti-Bacterial Agents; D010402:Penicillin G Procaine; D000667:Ampicillin