Reversible 18-FDG-uptake defects on myocardial PET: Is this myocardial resurrection?
Because it can accurately detect preserved glucose metabolism even in the hypoperfused or stunned myocardium, 18-FDG-PET is considered as the gold standard of myocardial viability assessment. In tako-tsubo cardiomyopathy, a presumed condition of stunning, absence of glucose metabolism however is not a marker of death. This sheds a critical light on 18-FDG-PET as a gold standard for viability.
De Boeck
Bart W L
BW
Verburg
Frederik A
FA
Hobbelink
Monique G G
MG
Velthuis
Birgitta
B
Melman
Paul G
PG
Cramer
Maarten-Jan M
MJ
D000368:Aged; D005260:Female; D019788:Fluorodeoxyglucose F18 / Q000378:metabolism*; D006801:Humans; D017682:Myocardial Stunning / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000378:metabolism; D009206:Myocardium / Q000378:metabolism*; D049268:Positron-Emission Tomography / Q000379:methods*; D015899:Tomography, Emission-Computed, Single-Photon / Q000379:methods
D019788:Fluorodeoxyglucose F18