title: A literature review on biomaterials in sinus augmentation procedures.
abstract: BACKGROUND
  Sinus augmentation is a common procedure to increase bone volume and allow for proper implant placement in the atrophic posterior maxilla. Although the patient's own bone is considered the best grafting material, various synthetic or bovine-derived alternatives are used to simplify the grafting procedure.
  
  
  OBJECTIVE
  The overall objective of this review was to assess the efficacy of different graft materials used in sinus augmentation procedures as demonstrated in animal studies.
  
  
  METHODS
  A specific and sensitive database was initially created via PUBMED, focusing on studies published in English peer-reviewed journals between 1995 and 2004 and kept updated until 2006.
  
  
  RESULTS
  Twenty-six articles were available for comparison and discussion; none concerned the use of alloplastic materials; 24 were comparative histomorphometric; and two were biomechanical studies. Because of a great variability in study designs, different implant types, great range in follow-up, and lack of specific integration or loading period, a comparison of the studies and the biomaterials used was difficult.
  
  
  CONCLUSIONS
  In general, autogenous bone is the most predictable material of choice for augmentation procedures, despite a 40% resorption, because it is highly osteoconductive and less dependent on sinus floor endosteal bone migration. The addition of bovine bone mineral to autogenous bone can be beneficial for graft success because it acts as a slowly resorbing space maintainer. Porous hydroxyapatite is suitable when mixed with autogenous bone because it enhances bone formation and bone-to-implant contact in augmented sinuses. Histological evaluation showed that demineralized freeze-dried bone is inferior to other materials. Within the limitation of the animal studies examined in this review and only based on histological examination, the initial osseointegration of implants seems independent of the biomaterial used in grafting procedures.
authors: Department of Maxillofacial Surgery, Dental School University of Ghent, Belgium. hilde.browaeys@ugent.be
authors: Hilde
authors: H
authors: Browaeys
authors: Peter
authors: P
authors: Bouvry
authors: Hugo
authors: H
authors: De Bruyn
mesh_terms: D000540:Alveolar Ridge Augmentation / Q000379:methods*; D000818:Animals; D001672:Biocompatible Materials / Q000627:therapeutic use*; D018786:Bone Substitutes / Q000627:therapeutic use*; D016025:Bone Transplantation; D036341:Intercellular Signaling Peptides and Proteins / Q000627:therapeutic use; D008437:Maxilla / Q000601:surgery*; D008443:Maxillary Sinus / Q000601:surgery*
chemical_list: D001672:Biocompatible Materials; D018786:Bone Substitutes; D036341:Intercellular Signaling Peptides and Proteins