title: Stereospecific aziridination of olefins via electrophile-induced cyclization of gamma,delta-unsaturated imines and subsequent hydrolytic rearrangement.
abstract: The olefinic bond of gamma,delta-unsaturated aldehydes underwent a net aziridination through electrophile-induced cyclization and subsequent rearrangement of the resulting cyclic iminium salts: this methodology allows the stereospecific introduction of aziridine moieties into cyclic systems.
authors: Department of Organic Chemistry, Faculty of Bioscience Engineering, Ghent University, Belgium.
authors: Matthias
authors: M
authors: D'hooghe
authors: Mark
authors: M
authors: Boelens
authors: Johan
authors: J
authors: Piqueur
authors: Norbert
authors: N
authors: De Kimpe
mesh_terms: D000475:Alkenes / Q000737:chemistry*; D001388:Aziridines / Q000737:chemistry*; D003500:Cyclization; D006868:Hydrolysis; D007097:Imines / Q000737:chemistry*; D015394:Molecular Structure; D013237:Stereoisomerism
chemical_list: D000475:Alkenes; D001388:Aziridines; D007097:Imines