Investigating cellular stress responses--a multidisciplinary approach from basic science to therapeutics--report on the EuroSciCon (European Scientific Conferences) meeting.
The meeting on "Investigating cellular stress responses--a multidisciplinary approach from basic science to therapeutics" was held in London on 13 October 2006. The purpose of this 1-day meeting was to bring together European scientists investigating the immune biology of stress proteins and their potential clinical applications. The main topics included: the role of heat shock proteins (Hsps) in bacterial infections; the role of Hsps with a molecular mass of about 70 kDa in cancer therapy and in prediction of the clinical outcome following allogeneic hematopoietic stem cell transplantation; the quality and duration of stress as a danger signal for the initiation of a stress response; the mechanism of Hsp-protein interaction; and Hsp export from tumor cells in secretory granules.
Bogunia-Kubik
Katarzyna
K
L. Hirszfeld Institute of Immunology and Experimental Therapy, Laboratory and Department of Clinical Immunology, Polish Academy of Sciences, Wroclaw, Poland. bogunia@iitd.pan.wroc.pl
Multhoff
Gabriele
G
D000818:Animals; D001424:Bacterial Infections / Q000378:metabolism; D066246:ErbB Receptors / Q000235:genetics; D018840:HSP70 Heat-Shock Proteins / Q000235:genetics / Q000378:metabolism; D018869:Heat-Shock Response; D018380:Hematopoietic Stem Cell Transplantation; D006801:Humans; D007113:Immunity, Innate / Q000276:immunology; D021381:Protein Transport; D015533:Transcriptional Activation / Q000235:genetics
D018840:HSP70 Heat-Shock Proteins; D066246:ErbB Receptors
Immunobiology. 2000 Sep;202(3):254-66
11045661
Transplantation. 2006 Oct 27;82(8):1116-7
17060867
Dement Geriatr Cogn Disord. 2001 Sep-Oct;12(5):309-13
11455131
Brain Res. 2001 Sep 28;914(1-2):66-73
11578598
Clin Exp Immunol. 2002 Mar;127(3):553-9
11966775
Crit Rev Immunol. 2002;22(4):251-68
12678427
Transplantation. 2003 Sep 15;76(5):849-53
14501866
J Endotoxin Res. 2003;9(5):331-5
14577851
Cell Stress Chaperones. 2003 Fall;8(3):272-86
14984061
Biochem J. 2004 Jul 15;381(Pt 2):527-36
15040785
Biochem Soc Trans. 2004 Aug;32(Pt 4):636-9
15270695
J Exp Med. 2004 Aug 16;200(4):425-35
15314073
Biochem Biophys Res Commun. 2004 Nov 12;324(2):511-7
15474457
FASEB J. 2004 Nov;18(14):1636-45
15522909
Cell Death Differ. 2005 Jan;12(1):38-51
15592361
J Biol Chem. 2005 Feb 11;280(6):4037-47
15546885
Transplantation. 2005 Apr 15;79(7):815-20
15818324
Immunology. 2005 Jun;115(2):231-8
15885129
J Biol Chem. 2005 Jun 17;280(24):23349-55
15826944
Cancer Res. 2005 Jun 15;65(12):5238-47
15958569
Dokl Biol Sci. 2005 Mar-Apr;401:158-9
16003886
J Immunol. 2005 Sep 1;175(5):2900-12
16116176
Blood. 2006 Feb 15;107(4):1636-42
16263790
J Biol Chem. 2006 Mar 17;281(11):7022-9
16415353
Clin Exp Immunol. 2006 Jul;145(1):183-9
16792689
Lancet. 2006 Sep 2;368(9538):855-63
16950363
J Biol Chem. 2006 Oct 13;281(41):31002-11
16880211
Nat Immunol. 2001 Apr;2(4):338-45
11276205