[Morphological observation on gastric mucosa membrane of patients with gastric ulcer treated with combined use of Qifang Weitong Powder and omeprazole].
OBJECTIVE
To observe the histological changes of gastric mucosa in patients with active gastric ulcer before and after treatment by Qifang Weitong Powder combined with omeprazole (QWP-Op).


METHODS
Sixty patients were equally randomized into the treated group and the control group. They were all treated in the 1st week by the Helicobacter pylori eradication triad regimen. From the 2nd to 6th week, the study group re-ceived QWP-Op therapy, and the control group was given Omeprazole alone.Biopsy specimens were obtained around ulcer area before and after treatment for histological observation on changes of gastric mucosa membrane.


RESULTS
The improvement of mucosal thickness and glandular morphology was better in the treated group than that in the control group (P <0.05).


CONCLUSIONS
QWP-Op therapy can improve the histological quality of ulcer healing and restore the morphological structure of gastric mucosa in patients with active gastric ulcer.
Deng
Chang
C
The First Affiliated Hospital of Guangxi TCM College, Nanning. dengchangguangxi@tom.com
Luo
Wei-sheng
WS
Li
Gui-xian
GX
D000328:Adult; D000897:Anti-Ulcer Agents / Q000627:therapeutic use; D001707:Biopsy, Needle; D004359:Drug Therapy, Combination; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D005753:Gastric Mucosa / Q000473:pathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009853:Omeprazole / Q000627:therapeutic use*; D008517:Phytotherapy; D011208:Powders; D013276:Stomach Ulcer / Q000188:drug therapy* / Q000473:pathology; D016896:Treatment Outcome; D055815:Young Adult
D000897:Anti-Ulcer Agents; D004365:Drugs, Chinese Herbal; D011208:Powders; C533471:qifang weitong; D009853:Omeprazole