title: [Vitaprost forte in the therapy of patients with prostatic adenoma].
abstract: Active substance of the drug vitaprost is a complex of water-soluble biologically active peptides isolated from bovine prostatic gland. Prostatic extract has an organotropic effect in respect to the prostatic gland. It inhibits proliferative activity of cells and, therefore, development of prostatic adenoma, reduces edema and inflammation activity in prostatic diseases. Our study has shown that rectal suppositories vitaprost forte, as monotherapy of prostatic adenoma, produces a statistically significant moderate decrease of prostate size. The resultant infravesical obstruction also diminished this manifesting with increased maximal and mean volumetric urine flow rate and low volume of residual urine. A decline in obstructive and irritative symptoms due to vitaprost forte was confirmed by IPSS scores showing deterioration of quality of life. Rectal suppositories vitaprost forte can be used as monotherapy of prostatic adenoma in patients with moderate infravesical obstruction irrespective of age and concurrent diseases.
authors.forename: A A
authors.initials: AA
authors.lastname: Kamalov
authors.forename: E A
authors.initials: EA
authors.lastname: Efremov
authors.forename: S D
authors.initials: SD
authors.lastname: Dorofeev
authors.forename: Ia I
authors.initials: IaI
authors.lastname: Mel'nik
authors.forename: D A
authors.initials: DA
authors.lastname: Okhobotov
mesh_terms: D000818:Animals; D002417:Cattle; D004334:Drug Administration Schedule; D006801:Humans; D008297:Male; D009929:Organ Size; D010455:Peptides / Q000008:administration & dosage / Q000627:therapeutic use*; D011467:Prostate / Q000737:chemistry / Q000473:pathology; D011470:Prostatic Hyperplasia / Q000188:drug therapy*; D013449:Sulfonamides / Q000008:administration & dosage / Q000627:therapeutic use; D013488:Suppositories; D000077409:Tamsulosin; D016896:Treatment Outcome
chemical_list: D010455:Peptides; D013449:Sulfonamides; D013488:Suppositories; C524164:Vitaprost; D000077409:Tamsulosin