Ultrasound measurement of gallbladder wall thickening as a diagnostic test and prognostic indicator for severe dengue in pediatric patients.
Gallbladder wall thickening measured by ultrasound was significantly associated with severe dengue, as well as with hallmark features of thrombocytopenia and elevated hematocrit/hemoconcentration, in children with suspected dengue in Nicaragua. We demonstrate that gallbladder wall thickening serves as a clinically relevant diagnostic test and prognostic indicator of severe dengue in pediatric populations.
Colbert
James A
JA
Stanford University School of Medicine, Stanford, CA, USA.
Gordon
Aubree
A
Roxelin
Rigoberto
R
Silva
Sheyla
S
Silva
Javier
J
Rocha
Crisanta
C
Harris
Eva
E
D000293:Adolescent; D000906:Antibodies / Q000097:blood; D002648:Child; D002675:Child, Preschool; D003715:Dengue / Q000175:diagnosis / Q000000981:diagnostic imaging*; D003716:Dengue Virus / Q000276:immunology / Q000302:isolation & purification; D005260:Female; D005704:Gallbladder / Q000000981:diagnostic imaging* / Q000473:pathology; D006776:Hospitals, Pediatric; D006801:Humans; D007075:Immunoglobulin M / Q000097:blood; D008297:Male; D009527:Nicaragua; D011379:Prognosis; D014463:Ultrasonography
D000906:Antibodies; D007075:Immunoglobulin M