Congenital duplication of the palm syndrome.
In this paper, we report a new case of congenital duplication of the palm syndrome (also known as limb/pelvis-hypoplasia/aplasia syndrome) and review previously reported cases and Wnt 7a gene mutations associated with that syndrome. Finally, we review the embryonic molecular events of limb development to explain the clinical features of the syndrome and to explain why the Swanson classification of duplication of the hand should be extended to include the dorsoventral duplication.
Al-Qattan
M M
MM
Department of Surgery, King Saud University, Riyadh, Saudi Arabia. moqattan@hotmail.com
Eyaid
Wafaa
W
Al-Balwi
Mohammed
M
D000015:Abnormalities, Multiple; D000293:Adolescent; D005121:Extremities / Q000196:embryology*; D005260:Female; D006228:Hand Deformities, Congenital / Q000145:classification / Q000175:diagnosis* / Q000235:genetics; D006801:Humans; D009154:Mutation; D013577:Syndrome; D051153:Wnt Proteins / Q000235:genetics*
C092778:WNT7A protein, human; D051153:Wnt Proteins