title: [Thrombotic complications of sepsis and their pharmacological prophylaxis].
abstract: Patients with severe sepsis are at increased risk for developing thrombembolic phenomena. This article aims to clarify the association between systemic inflammation activation and coagulation, pathogenesis of coagulation abnormalities during severe sepsis. The article reviews incidence and deep venous thrombosis risk factors among these patients and summarizes recent evidence-based guidelines for deep venous thrombosis prophylaxis.
authors.affiliation: Trombotické centrum a Centrální hematologické laboratore VFN, Praha. necasova.zuzana@vfn.cz
authors.forename: Z
authors.initials: Z
authors.lastname: Zenáhlíková
authors.forename: J
authors.initials: J
authors.lastname: Výborný
authors.forename: Z
authors.initials: Z
authors.lastname: Uchytil
authors.forename: Z
authors.initials: Z
authors.lastname: Krska
authors.forename: J
authors.initials: J
authors.lastname: Mazoch
authors.forename: I
authors.initials: I
authors.lastname: Malíková
authors.forename: J
authors.initials: J
authors.lastname: Kvasnicka
mesh_terms: D001777:Blood Coagulation; D006801:Humans; D011655:Pulmonary Embolism / Q000209:etiology* / Q000517:prevention & control; D018805:Sepsis / Q000097:blood / Q000150:complications*; D020246:Venous Thrombosis / Q000209:etiology* / Q000517:prevention & control