Recurrent massive subcutaneous hemorrhage in neurofibromatosis type 1: a case report.
Neurofibromatosis type 1 (NF-1) is an autosomal dominant disorder that has three major features: multiple neural tumors, cafe-au-lait spots, and pigmented iris hamartomas (Lisch nodules). The purpose of this case report is to advise physicians of the danger associated with the progression of fast-onset massive hemorrhage to hemodynamic instability, which mandates rapid treatment to prevent the development of a life-threatening condition. A 64-yr-old woman with NF-1 was admitted to the Emergency Department (ED) because of a rapidly growing, 10 x 5 x 3 cm-sized mass on the left back area. She had previously undergone surgery for a large subcutaneous hematoma, which had developed on her right back area 30 yr before. She became hemodynamically unstable with hypotension during the next 3 hr after admission to ED. Resuscitation and blood transfusion were done, and the hematoma was surgically removed. The mass presented as a subcutaneous, massive hematoma with pathologic findings of neurofibroma. We report a case of NF-1 that presented as recurrent, massive, subcutaneous hemorrhage on the back region combined with hypovolemic shock.
Baek
Sung Hoon
SH
Department of Emergency Medicine, College of Medicine, Inha University, Incheon, Korea.
Kim
Ji Hye
JH
Kim
Jun Sig
JS
Han
Seung Baik
SB
Cho
Jung Soo
JS
Yoon
Yong Han
YH
Kim
Lucia
L
D003937:Diagnosis, Differential; D005260:Female; D006406:Hematoma / Q000209:etiology / Q000473:pathology; D006470:Hemorrhage / Q000209:etiology* / Q000473:pathology; D006801:Humans; D008875:Middle Aged; D009456:Neurofibromatosis 1 / Q000150:complications* / Q000473:pathology; D012008:Recurrence; D012871:Skin Diseases / Q000209:etiology* / Q000473:pathology; D014057:Tomography, X-Ray Computed