title: Nucleotide formation as a determinant of 5-Fluorouracil response in mouse leukemias.
abstract: Survival of mice bearing different transplantable leukemias and treated with 5-fluorouracil was compared with accumulation of drug nucleotides in vitro. There was significant correlation,suggesting that cellular capacity for conversion of the drug to nucleotides is a major determinant of inherent drug sensitivity of these leukemias.
authors.forename: D
authors.initials: D
authors.lastname: Kessed
authors.forename: T C
authors.initials: TC
authors.lastname: Hall
authors.forename: I
authors.initials: I
authors.lastname: Wodinsky