Disease modification in chronic obstructive pulmonary disease.
Chronic obstructive pulmonary disease (COPD) is a preventable and treatable disease in which patients experience a progressive decline in lung function, worsening exercise capacity, and frequent exacerbations. Based on clinical evidence, the progression of COPD could be modified by focus on earlier diagnosis; risk reduction through smoking cessation; symptom reduction with pharmacotherapy, improving health-related quality of life, and pulmonary rehabilitation; and decreasing complications by reducing exacerbations. Smoking cessation has been shown to slow lung function decline and reduce mortality, including deaths due to cardiovascular disease, lung cancer, and other respiratory disease (including COPD).
Anzueto
Antonio
A
Department of Medicine, University of Texas Health Science Center, 7400 Merton Minter Boulevard, 111 East, San Antonio, TX 78229, USA. anzueto@uthscsa.edu
D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use*; D005540:Forced Expiratory Flow Rates / Q000502:physiology; D006801:Humans; D029424:Pulmonary Disease, Chronic Obstructive / Q000188:drug therapy / Q000503:physiopathology / Q000517:prevention & control*; D016540:Smoking Cessation / Q000379:methods*; D016896:Treatment Outcome
D000319:Adrenergic beta-Antagonists