First detection of G12 rotaviruses in newborns with neonatal rotavirus infection at all India Institute of Medical Sciences, New Delhi, India.
Rotavirus genotype G12 strains were detected for the first time among newborns with asymptomatic rotavirus infection (74% of 39 rotavirus strains isolated from the infected infants were genotype G12) in the nursery of the All India Institute of Medical Sciences during a period from 2005 to 2006. Sequence analysis of the VP7 genes from these neonatal strains indicated a high level of homology to other G12 strains reported worldwide, suggesting the recent emergence of these strains in humans. Such nosocomial infections of newborns represent a potential source of introduction of novel rotavirus serotypes into the community.
Ray
Pratima
P
Center for Diarrheal Disease Research, Department of Pediatrics, All India Institute of Medical Sciences, New Delhi, India. pratimaray@gmail.com
Sharma
S
S
Agarwal
R K
RK
Longmei
K
K
Gentsch
J R
JR
Paul
V K
VK
Glass
R I
RI
Bhan
M K
MK
D000956:Antigens, Viral / Q000235:genetics; D036022:Capsid Proteins / Q000235:genetics; D005838:Genotype; D006801:Humans; D007231:Infant, Newborn; D012401:Rotavirus / Q000145:classification / Q000302:isolation & purification*; D012400:Rotavirus Infections / Q000821:virology*
D000956:Antigens, Viral; D036022:Capsid Proteins; C050779:VP7 protein, Rotavirus