title: Analysis of salicylic acid based on the fluorescence enhancement of the As(III)-salicylic acid system.
abstract: A new, simple and sensitive spectrofluorimetric method for the determination of salicylic acid (lambda(ex)=315 nm, lambda(em) = 408 nm) using As(III) as a sensitizing reagent has been investigated by measuring the increase of fluorescence intensity of salicylic acid due to the complexation of As(III)-salicylic acid in presence of sodium dodecyl sulfate (SDS) 10(-3) M. Under optimum conditions, a significant relationship was obtained between the fluorescence intensity and salicylic acid concentration. A linear calibration curve was obtained in the range 13.8-13812 microg l(-1) with product-moment correlation coefficient (R) 0.99985 and detection limit 4.2 microg l(-1). The R.S.D. is 2.35% (n=5). The method was applied successfully to the determination of salicylic acid in human serum.
authors.affiliation: Department of Chemistry, Kyungpook National University, Taegu 702-701, Republic of Korea.
authors.forename: Mohammad Mainul
authors.initials: MM
authors.lastname: Karim
authors.forename: Hwa Suk
authors.initials: HS
authors.lastname: Lee
authors.forename: Young Sun
authors.initials: YS
authors.lastname: Kim
authors.forename: Hyun Sook
authors.initials: HS
authors.lastname: Bae
authors.forename: Sang Hak
authors.initials: SH
authors.lastname: Lee