Currarino syndrome as an etiology of a neonatal Escherichia coli meningitis.
We report the case of a 29-day-old baby girl in whom Escherichia coli meningitis led to the diagnosis of Currarino syndrome (CS) (OMIM 176450), an autosomal-dominant genetic disorder associated with sacral agenesis, anorectal malformation, presacral masses and spinal cord malformations. Her condition improved with antibiotics and early surgical treatment. A familial study identified other genetically related individuals with similar symptoms.
Fleury
J
J
Clinique Médicale Pédiatrique, Hôpital Mère Enfant CHU Nantes, CHU Nantes, France.
Picherot
G
G
Cretolle
C
C
Podevin
G
G
David
A
A
Caillon
J
J
Roze
J C
JC
Gras-le Guen
C
C
D000015:Abnormalities, Multiple; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D020814:Meningitis, Escherichia coli / Q000209:etiology*; D012007:Rectum / Q000002:abnormalities*; D012447:Sacrum / Q000002:abnormalities*; D013577:Syndrome