Coinfection of invasive pulmonary aspergillosis and pneumocystis jiroveci pneumonia in a non-HIV patient.
Invasive pulmonary aspergillosis (IPA) and pneumocystis jiroveci pneumonia (PCP) are life-threatening opportunistic infections that occur in immunocompromised hosts. Early diagnosis and treatment of these opportunistic infections is essential to the survival of immunocompromised patients. We report a 60-year-old man undergoing short-term steroid therapy after surgical resection of a brain tumor infected with combined invasive pulmonary aspergillosis and pneumocystis jiroveci pneumonia diagnosed by bronchoscopy with bronchoalveolar lavage. Our case demonstrated that short-term systemic steroid therapy in non-HIV patients with underlying chronic lung conditions and malignancies was a risk factor for IPA and PCP, and for a combination of these infections.
Kaira
Kyoichi
K
Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Maebachi, Gunma 371-8511, Japan. kkaira1970@yahoo.co.jp
Shinomiya
Yasuyuki
Y
Takahashi
Yuga
Y
Iida
Tomohiro
T
Yanagitani
Noriko
N
Sunaga
Noriaki
N
Hisada
Takeshi
T
Ishizuka
Tamotsu
T
Mori
Masatomo
M
D001228:Aspergillosis / Q000150:complications* / Q000000981:diagnostic imaging; D015658:HIV Infections / Q000382:microbiology; D006801:Humans; D008172:Lung Diseases, Fungal / Q000150:complications* / Q000000981:diagnostic imaging; D008297:Male; D008875:Middle Aged; D045363:Pneumocystis carinii; D011020:Pneumonia, Pneumocystis / Q000150:complications* / Q000000981:diagnostic imaging; D011859:Radiography