title: Haemodialysis dose and serum bicarbonate (chapter 7).
abstract: Data from 21 renal units was insufficient to allow analyses of the dose of dialysis in those units. Amongst the remainder, there is evidence of a progressive increase in the proportion of patients meeting the Renal Association audit standard for urea reduction ratio (URR). In the UK as a whole, 81% of prevalent haemodialysis patients met the standard for URR in 2005. Greater achievement of the standard in a given unit is associated with a higher median URR in that unit, although there is some evidence that some units have been able to narrow the distribution of achieved URR values. Achievement of the standard remains, as in previous years' Reports, less common amongst patients recently established on haemodialysis compared with those established on haemodialysis for longer. Correction of acidosis, as measured by serum bicarbonate concentration remains highly variable, although there is continued uncertainty about the interpretation of routine measurements of venous serum bicarbonate concentration in haemodialysis patients. Overall, approximately 64% of UK haemodialysis patients, and 50% of peritoneal dialysis patients met the Renal Association standard for serum bicarbonate in 2005.
authors.affiliation: UK Renal Registry, Bristol. charlie.tomson@nbt.nhs.uk
authors.forename: Charlie
authors.initials: C
authors.lastname: Tomson
authors.forename: David
authors.initials: D
authors.lastname: Thomas
authors.forename: Raman
authors.initials: R
authors.lastname: Rao
authors.forename: Dirk
authors.initials: D
authors.lastname: van Schalkwyk
authors.forename: David
authors.initials: D
authors.lastname: Ansell
mesh_terms: D000138:Acidosis / Q000097:blood / Q000517:prevention & control*; D001639:Bicarbonates / Q000097:blood*; D002908:Chronic Disease; D015314:Dialysis Solutions / Q000008:administration & dosage*; D019983:Guideline Adherence / Q000706:statistics & numerical data*; D006801:Humans; D007674:Kidney Diseases / Q000097:blood / Q000628:therapy; D012042:Registries / Q000706:statistics & numerical data; D006435:Renal Dialysis / Q000379:methods / Q000592:standards / Q000706:statistics & numerical data*; D016896:Treatment Outcome; D006113:United Kingdom
chemical_list: D001639:Bicarbonates; D015314:Dialysis Solutions