title: Gallbladder perforation in a patient on steroid therapy.
abstract: Gallbladder perforation is a serious clinical condition. A definitive diagnosis is contentious before surgery. We discuss a case where a young patient with Crohn's disease taking oral steroids presented with an acute abdomen. CT scan demonstrated a perforated gallbladder without evidence of gallstones. The patient underwent an emergency cholecystectomy and peritoneal lavage. The history and clinical findings of this patient are reviewed to highlight perforation of the gallbladder in relation to steroid therapy.
authors.affiliation: Department of Surgery, Craigavon Area Hospital, Portadown, Northern Ireland, UK. imranandrabi@gmail.com
authors.forename: Syed Imran
authors.initials: SI
authors.lastname: Andrabi
authors.forename: Jawad
authors.initials: J
authors.lastname: Ahmad
authors.forename: Munir A
authors.initials: MA
authors.lastname: Rathore
authors.forename: Ahmed A
authors.initials: AA
authors.lastname: El-Hakeem
mesh_terms: D000328:Adult; D002763:Cholecystectomy; D003424:Crohn Disease / Q000188:drug therapy*; D005705:Gallbladder Diseases / Q000000981:diagnostic imaging / Q000209:etiology* / Q000601:surgery; D005938:Glucocorticoids / Q000009:adverse effects*; D006801:Humans; D008297:Male; D010533:Peritoneal Lavage; D011239:Prednisolone / Q000009:adverse effects*; D012422:Rupture, Spontaneous; D014057:Tomography, X-Ray Computed
chemical_list: D005938:Glucocorticoids; D011239:Prednisolone