title: Ultrasound measurement of gallbladder wall thickening as a diagnostic test and prognostic indicator for severe dengue in pediatric patients.
abstract: Gallbladder wall thickening measured by ultrasound was significantly associated with severe dengue, as well as with hallmark features of thrombocytopenia and elevated hematocrit/hemoconcentration, in children with suspected dengue in Nicaragua. We demonstrate that gallbladder wall thickening serves as a clinically relevant diagnostic test and prognostic indicator of severe dengue in pediatric populations.
authors.affiliation: Stanford University School of Medicine, Stanford, CA, USA.
authors.forename: James A
authors.initials: JA
authors.lastname: Colbert
authors.forename: Aubree
authors.initials: A
authors.lastname: Gordon
authors.forename: Rigoberto
authors.initials: R
authors.lastname: Roxelin
authors.forename: Sheyla
authors.initials: S
authors.lastname: Silva
authors.forename: Javier
authors.initials: J
authors.lastname: Silva
authors.forename: Crisanta
authors.initials: C
authors.lastname: Rocha
authors.forename: Eva
authors.initials: E
authors.lastname: Harris
mesh_terms: D000293:Adolescent; D000906:Antibodies / Q000097:blood; D002648:Child; D002675:Child, Preschool; D003715:Dengue / Q000175:diagnosis / Q000000981:diagnostic imaging*; D003716:Dengue Virus / Q000276:immunology / Q000302:isolation & purification; D005260:Female; D005704:Gallbladder / Q000000981:diagnostic imaging* / Q000473:pathology; D006776:Hospitals, Pediatric; D006801:Humans; D007075:Immunoglobulin M / Q000097:blood; D008297:Male; D009527:Nicaragua; D011379:Prognosis; D014463:Ultrasonography
chemical_list: D000906:Antibodies; D007075:Immunoglobulin M