Ethnopharmacology and malaria: new hypothetical leads or old efficient antimalarials?
New treatments are urgently needed to curb and eradicate malaria in developing countries. As most people living in malarial endemic areas use traditional medicine to fight this disease, why have new treatments not emerged recently from ethnopharmacology-oriented research? The rationale and limitations of the ethnopharmacological approach are discussed in this paper, focusing on ethnopharmacology methodologies and techniques used for assessing botanical samples for their antimalarial properties. Discrepancies often observed between strong ethnopharmacological reputation and laboratory results are discussed, as well as new research perspectives.
Bourdy
G
G
Laboratoire de Pharmacochimie des Substances Naturelles et Pharmacophores Redox, UMR-152 (IRD - Université Paul Sabatier, Université de Toulouse 3), Mission IRD, Casilla 18-1209, Lima 18, Peru.
Willcox
M L
ML
Ginsburg
H
H
Rasoanaivo
Ph
P
Graz
B
B
Deharo
E
E
D000962:Antimalarials / Q000627:therapeutic use*; D003906:Developing Countries; D019448:Ethnobotany; D006801:Humans; D008288:Malaria / Q000188:drug therapy / Q000517:prevention & control*; D008519:Medicine, Traditional; D010946:Plants, Medicinal; D012106:Research
D000962:Antimalarials