title: Toxicologic aspects of deaths due to falls from height.
abstract: A prospective study of 161 victims of falls from height is reported. The aim was to determine the interest of systematic qualitative and quantitative toxicological analysis in such fatalities. The primary cause of death was suicide (84.5%), followed by accidents (7%) and homicide (1%). In the remaining 7.5%, cause of death was undetermined. In the suicides, there was evidence of psychotropic medicines in 57% of the observations, with a much higher proportion of benzodiazepines and antidepressants in women than in men. Quantitative toxicologic analysis showed overdosing on medication in 16 suicide victims, with toxic levels in 11 of these. Systematic qualitative and quantitative toxicologic analysis made a significant contribution to the diagnosis of suicide by revealing either an unknown psychiatric treatment or a toxic level.
authors.affiliation: Université de Lyon, and the Hospices Civils de Lyon, Département de Médecine Légale, Hôpital Edouard-Herriot, Lyon, France. laurent.fanton@adm.univ-lyon1.fr
authors.forename: L
authors.initials: L
authors.lastname: Fanton
authors.forename: F
authors.initials: F
authors.lastname: Bévalot
authors.forename: P
authors.initials: P
authors.lastname: Schoendorff
authors.forename: S
authors.initials: S
authors.lastname: Lalliard
authors.forename: K
authors.initials: K
authors.lastname: Jdeed
authors.forename: D
authors.initials: D
authors.lastname: Malicier
mesh_terms: D000058:Accidental Falls / Q000401:mortality*; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002188:Cannabis; D002423:Cause of Death; D002492:Central Nervous System Depressants / Q000097:blood*; D002648:Child; D062787:Drug Overdose; D000431:Ethanol / Q000097:blood*; D005260:Female; D053593:Forensic Toxicology; D005602:France / Q000453:epidemiology; D006708:Homicide / Q000706:statistics & numerical data*; D006801:Humans; D008297:Male; D008875:Middle Aged; D004364:Pharmaceutical Preparations / Q000097:blood; D011446:Prospective Studies; D011619:Psychotropic Drugs / Q000097:blood*; D015813:Substance Abuse Detection; D013405:Suicide / Q000706:statistics & numerical data*
chemical_list: D002492:Central Nervous System Depressants; D004364:Pharmaceutical Preparations; D011619:Psychotropic Drugs; D000431:Ethanol