title: Plasma concentrations of voriconazole in falcons.
abstract: Doses of 12.5 mg voriconazole/kg bodyweight administered every 12 hours by crop gavage to six falcons for 14 days provided peak plasma concentrations of more than 1 microg/ml, but the trough concentrations were lower and sometimes undetectable. Administering the same doses incorporated into meat that was fed to one falcon for seven days and to three falcons for up to 91 days provided similar plasma concentrations.
authors.affiliation: Clinic for Birds and Reptiles, University of Leipzig, An den Tierkliniken 15, D-04103 Leipzig, Germany.
authors.forename: V
authors.initials: V
authors.lastname: Schmidt
authors.forename: F
authors.initials: F
authors.lastname: Demiraj
authors.forename: A
authors.initials: A
authors.lastname: Di Somma
authors.forename: T
authors.initials: T
authors.lastname: Bailey
authors.forename: F R
authors.initials: FR
authors.lastname: Ungemach
authors.forename: M-E
authors.initials: ME
authors.lastname: Krautwald-Junghanns
mesh_terms: D000818:Animals; D000935:Antifungal Agents / Q000008:administration & dosage / Q000097:blood* / Q000493:pharmacokinetics; D001228:Aspergillosis / Q000188:drug therapy / Q000662:veterinary*; D001682:Biological Availability; D001715:Bird Diseases / Q000188:drug therapy*; D004305:Dose-Response Relationship, Drug; D046093:Falconiformes / Q000097:blood*; D005260:Female; D008297:Male; D011743:Pyrimidines / Q000008:administration & dosage / Q000097:blood* / Q000493:pharmacokinetics; D016896:Treatment Outcome; D014230:Triazoles / Q000008:administration & dosage / Q000097:blood* / Q000493:pharmacokinetics; D065819:Voriconazole
chemical_list: D000935:Antifungal Agents; D011743:Pyrimidines; D014230:Triazoles; D065819:Voriconazole