title: [Positive sentinel node biopsy in breast cancer: is axillary surgery necessary in all cases?].
abstract: Our retrospective study analyzes various factors to evaluate the risk of invasion of the not sentinel node when the sentinel node biopsy is positive in the infiltrated breast cancers. We compared in single varied then multivaried analysis, various parameters between two groups: positive not sentinel nodes and negative not sentinel nodes among 180 cases of positive sentinel node biopsy between 2001 and 2004. At the time of the single varied analysis, seem to be risk factors of non sentinel node involvement: the histopronostic SBRIII rank, positive a HER2neu status, the presence of extracapsulal node extension and infiltration of the sentinel node by a macrometastasis. The tumoral embol, the absence of hormonal receivers, a tumoral size > 10 mm and the number of sentinel node taken appear at the limit of the significativity. In multivaried analysis, SBRIII rank and the presence of an extracapsular node extension remain related to non sentinel node involvement. The histological type, association with a CIS, the size of the sentinel nodes, the number of positive sentinel nodes and the year of surgery are nonsignificant. Additional axillairy clearing out at the time of a positive node sentinel biopsy should be discussed according to different criteria determined by a precise histological analysis.
authors.affiliation: Service de chirurgie, CRLC Val d'Aurelle-Paul Lamarque, 208, rue des Apothicaires, Parc Euromédecine, 34298 Montpellier Cedex 5. frederic.trentini@vadorel.fnclcc.fr
authors.forename: Frédéric
authors.initials: F
authors.lastname: Trentini
authors.forename: Bernard
authors.initials: B
authors.lastname: Saint-Aubert
authors.forename: François
authors.initials: F
authors.lastname: Quenet
authors.forename: Marian
authors.initials: M
authors.lastname: Gutowski
authors.forename: Frédéric
authors.initials: F
authors.lastname: Bibeau
authors.forename: J
authors.initials: J
authors.lastname: Simony-Lafontaine
authors.forename: Marie-Christine
authors.initials: MC
authors.lastname: Chateau
authors.forename: Didier
authors.initials: D
authors.lastname: Pourquier
authors.forename: Majida
authors.initials: M
authors.lastname: Eslimani
authors.forename: Christophe
authors.initials: C
authors.lastname: Delfour
authors.forename: Sophie
authors.initials: S
authors.lastname: Gourgou
authors.forename: Simon
authors.initials: S
authors.lastname: Thezenas
authors.forename: Philippe
authors.initials: P
authors.lastname: Rouanet
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000704:Analysis of Variance; D001365:Axilla; D001943:Breast Neoplasms / Q000473:pathology* / Q000601:surgery*; D004396:Coloring Agents; D005260:Female; D006801:Humans; D008197:Lymph Node Excision; D008207:Lymphatic Metastasis; D008875:Middle Aged; D012189:Retrospective Studies; D012394:Rosaniline Dyes; D021701:Sentinel Lymph Node Biopsy
chemical_list: D004396:Coloring Agents; D012394:Rosaniline Dyes; C008769:sulfan blue