title: Fine-scale genetic diversity among Burkholderia pseudomallei soil isolates in northeast Thailand.
abstract: Burkholderia pseudomallei soil isolates from northeast Thailand were genotyped using multiple-locus variable-number tandem repeat (VNTR) analysis (MLVA) and multilocus sequence typing (MLST). MLVA identified 19 genotypes within three clades, while MLST revealed two genotypes. These close genetic relationships imply a recent colonization followed by localized expansion, similar to what occurs in an outbreak situation.
authors.affiliation: Northern Arizona University, Department of Biological Sciences, Box 5640, Flagstaff, AZ 86011-5640, USA.
authors.forename: Jana M
authors.initials: JM
authors.lastname: U'ren
authors.forename: Heidie
authors.initials: H
authors.lastname: Hornstra
authors.forename: Talima
authors.initials: T
authors.lastname: Pearson
authors.forename: James M
authors.initials: JM
authors.lastname: Schupp
authors.forename: Benjamin
authors.initials: B
authors.lastname: Leadem
authors.forename: Shalamar
authors.initials: S
authors.lastname: Georgia
authors.forename: Rasana W
authors.initials: RW
authors.lastname: Sermswan
authors.forename: Paul
authors.initials: P
authors.lastname: Keim
mesh_terms: D001426:Bacterial Proteins / Q000235:genetics / Q000378:metabolism; D015373:Bacterial Typing Techniques; D016957:Burkholderia pseudomallei / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification; D004269:DNA, Bacterial / Q000032:analysis; D014644:Genetic Variation; D005838:Genotype; D018598:Minisatellite Repeats / Q000235:genetics; D012988:Soil Microbiology; D013785:Thailand
chemical_list: D001426:Bacterial Proteins; D004269:DNA, Bacterial