title: A clinical assessment of a patch test kit marketed to U.K. hairdressers for detecting hair dye allergy.
abstract: BACKGROUND
  In 2004 a U.K.-based company developed and marketed a patch test kit (Colourstart); Trichocare, Ridgmont, Beds, U.K.) for use by hairdressers. It is intended to assess whether clients have a 'problem with hair dye' and promotes itself as the 'only practical solution to sensitivity testing'. However, a patient presented with a hair dye reaction that had not been detected while using this patch test system.
  
  
  OBJECTIVE
  To assess the Colourstart system in the next seven consecutive patients presenting with a history of adverse reactions to hair dyes.
  
  
  METHODS
  The Colourstart system was tested in parallel with commercially available hair dye patch test reagents, where applicable.
  
  
  RESULTS
  Only three of seven patients allergic to p-phenylenediamine were detected using this system and one patient allergic to toluene-2,5-diamine sulphate was not detected using this system.
  
  
  CONCLUSIONS
  The results raise concerns about the sensitivity of this kit for consumer protection, but also wider questions about the regulation, use and interpretation of 'home diagnostic patch test kits' in general.
authors.affiliation: Contact and Environmental Dermatitis Unit, Amersham Hospital, Buckinghamshire Hospitals NHS Trust, Amersham HP7 0JD, UK. david.orton@buckshosp.nhs.uk
authors.forename: D I
authors.initials: DI
authors.lastname: Orton
mesh_terms: D000328:Adult; D000627:Aminophenols / Q000009:adverse effects; D017449:Dermatitis, Allergic Contact / Q000175:diagnosis* / Q000209:etiology; D003959:Diamines / Q000009:adverse effects; D005260:Female; D006202:Hair Dyes / Q000009:adverse effects; D006801:Humans; D008297:Male; D008875:Middle Aged; D010328:Patch Tests / Q000379:methods*; D010655:Phenylenediamines / Q000009:adverse effects; D012118:Resorcinols / Q000009:adverse effects; D012680:Sensitivity and Specificity; D014050:Toluene / Q000009:adverse effects; D006113:United Kingdom
chemical_list: D000627:Aminophenols; D003959:Diamines; D006202:Hair Dyes; D010655:Phenylenediamines; D012118:Resorcinols; D014050:Toluene; C031389:resorcinol