title: Vulnerability to air pollution health effects.
abstract: BACKGROUND
  Ambient air pollution can have adverse effects on the health of exposed populations, but individuals or groups are not equally vulnerable, and pollution reduction benefits are likely to be unevenly distributed within a population. While the use of total-population risks is a valid approach for public health protection, it is increasingly recognized that more attention on vulnerable groups is necessary. This paper describes population vulnerability to the health effects of air pollutants using risk analysis concepts and based on available evidence.
  
  
  METHODS
  Publications reporting air pollution health risks for specific sub-populations, or more conceptual discussions of vulnerability, were selected following a literature search of the PubMed database. Only studies in the context of developed countries were included. Information on population characteristics and factors that can influence risk was assessed from the perspective of the vulnerability framework, and was used to outline interactions with biological susceptibility, exposure, and social coping.
  
  
  RESULTS
  Population characteristics encompass several factors that interact and confer vulnerability. Age, for example, regarded as significant mostly in terms of physiology, also relates to exposure through behaviours and activities that can be more amenable to prevention. Children are recognized as a high-risk group but their vulnerability may differ by childhood stage, while pregnant women are not explicitly identified as a vulnerable group despite growing evidence for reproductive risks. Social-economic factors have received little attention, although they can affect coping capacity as well as interact with susceptibility and exposure to air pollution.
  
  
  CONCLUSIONS
  Evidence for vulnerability components often lies in different fields of study and has not been evaluated in an integrated manner. Better understanding of population vulnerability can improve the scientific basis to assess risks and develop policies or other health protection initiatives to reduce the impacts of air pollution.
authors.affiliation: Joint Research Centre, European Commission, Ispra (Va), Italy. anita@fghp.org
authors.forename: Anna
authors.initials: A
authors.lastname: Makri
authors.forename: Nikolaos I
authors.initials: NI
authors.lastname: Stilianakis
mesh_terms: D000367:Age Factors; D000368:Aged; D000393:Air Pollutants / Q000009:adverse effects*; D000397:Air Pollution / Q000009:adverse effects*; D002648:Child; D004781:Environmental Exposure / Q000009:adverse effects; D005260:Female; D006291:Health Policy; D006304:Health Status; D006801:Humans; D008297:Male; D011247:Pregnancy; D015980:Public Health Practice; D018570:Risk Assessment; D012307:Risk Factors; D012737:Sex Factors; D035862:Vulnerable Populations
chemical_list: D000393:Air Pollutants