Interrupted oligomerization revisited: simple and efficient one-pot multicomponent approach to versatile synthetic intermediates.
A novel multicomponent reaction allowing for a one-pot formation of three carbon-carbon bonds has been developed. It is based on in situ generation and anionic dimerization of methylenedithiane and produces a versatile synthetic equivalent of 4-hydroxy-1,3-alkanediones which, among other things, offers expeditious one-pot access to 3(2H)-furanones.
Valiulin
Roman A
RA
Department of Chemistry and Biochemistry, University of Denver, Denver, Colorado 80208, USA.
Halliburton
Logan M
LM
Kutateladze
Andrei G
AG