[High fetal irradiation: about one pregnant woman receiving infradiaphragmatic radiotherapy for Hodgkin lymphoma].
We report the case of a 19-year-old young woman for whom was discovered a pregnancy at the end of the irradiation for a Hodgkin lymphoma (stage IV bone Bb), initially treated by chemotherapy. The radiotherapy delivered 36 Gy in infra-diaphragmatic volumes (lombo-aortic, spleen, L5), beginning in a pregnant patient for less than 4 amenorrhea weeks. The calculated received fetal dose (literature data, measurement with software TPS, measurement on phantom) is high: it's between 2.8 and 5 Gy. With a current follow-up of 4 years since the radiotherapy's end, the patient is in complete remission and her child presents with a normal development for the age, in spite of the infradiaphragmatic irradiation.
Moreau
M V
MV
Service de radiothérapie, centre Alexis-Vautrin, 54511 Vandoeuvre-lès-Nancy, France. ginie_moreau@hotmail.com
Brunaud
C
C
Bologna
S
S
Marchesi
V
V
Hoffstetter
S
S
Peiffert
D
D
D000328:Adult; D003964:Diaphragm; D005260:Female; D005333:Fetus / Q000528:radiation effects*; D006689:Hodgkin Disease / Q000532:radiotherapy*; D006801:Humans; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000532:radiotherapy*; D011878:Radiotherapy / Q000009:adverse effects* / Q000379:methods*; D011879:Radiotherapy Dosage; D016896:Treatment Outcome