title: [Renal infarction and kidney rupture: complication of a massive cocaine intoxication in an intestinal carrier].
abstract: Major complications derived from the use of cocaine have been described, alter nasal or intravenous administration of the drug. These complications are related to vascular spasm and secondary organ damage. We present the case of an intestinal cocaine packer--in slang, "mule"--, who suffered massive absorption of the drug, resulting n bowel, liver and renal ischemia. This situation, previously undescribe in the literature, ended in kidney rupture. An attempt of embolization, was unsatisfactory, and nephrectomy was finally required. The patient recovered uneventfully, with progressive renal functional improvement. This case, albeit quite exceptional, is illustrative of several of the renal actions of cocaine, and reveals the effects of absorption of cocaine at the intestinal level.
authors.affiliation: Unidad de Diálisis, Fundación Jiménez Díaz/Capio, Universidad Autónoma de Madrid, Madrid, Spain. ccaramelo@fjd.es
authors.forename: C
authors.initials: C
authors.lastname: Caramelo
authors.forename: D
authors.initials: D
authors.lastname: López de Mendoza
authors.forename: F
authors.initials: F
authors.lastname: Ríos
authors.forename: M
authors.initials: M
authors.lastname: Corrales
authors.forename: J
authors.initials: J
authors.lastname: Urbano
authors.forename: A
authors.initials: A
authors.lastname: Ramos
authors.forename: C
authors.initials: C
authors.lastname: Pérez Calvo
mesh_terms: D000328:Adult; D003042:Cocaine / Q000378:metabolism / Q000506:poisoning*; D003415:Crime; D005547:Foreign Bodies / Q000150:complications*; D006801:Humans; D013287:Illicit Drugs / Q000378:metabolism / Q000506:poisoning*; D007238:Infarction / Q000139:chemically induced*; D007413:Intestinal Mucosa / Q000378:metabolism; D007422:Intestines / Q000098:blood supply; D007668:Kidney / Q000098:blood supply*; D008297:Male; D009392:Nephrectomy; D012422:Rupture, Spontaneous
chemical_list: D013287:Illicit Drugs; D003042:Cocaine