title: [Update in the management of persistent pulmonary hypertension of the newborn].
abstract: Persistent pulmonary hypertension of the newborn is a severe disease leading to persistent and refractory hypoxemia with bad outcomes. The introduction of inhaled nitric oxide therapy significantly improved short and long term prognosis of those infants. More recently, sildenafil also appeared promising, but regimen and indications still need to be delineated.
authors.affiliation: Université de Liège, CHR Citadelle, Liège, Belgique.
authors.forename: R
authors.initials: R
authors.lastname: Viellevoye
authors.forename: V
authors.initials: V
authors.lastname: Rigo
authors.forename: J
authors.initials: J
authors.lastname: Rigo
mesh_terms: D000280:Administration, Inhalation; D006801:Humans; D006976:Hypertension, Pulmonary / Q000188:drug therapy*; D007231:Infant, Newborn; D009569:Nitric Oxide / Q000008:administration & dosage*; D010879:Piperazines / Q000627:therapeutic use*; D011687:Purines / Q000627:therapeutic use; D000068677:Sildenafil Citrate; D013450:Sulfones / Q000627:therapeutic use*; D014665:Vasodilator Agents / Q000627:therapeutic use*
chemical_list: D010879:Piperazines; D011687:Purines; D013450:Sulfones; D014665:Vasodilator Agents; D009569:Nitric Oxide; D000068677:Sildenafil Citrate