[Acute retinal necrosis in an acute leukemia pediatric patient].
Acute retinal necrosis (ARN) is a serious condition that can impair vision. It mostly occurs in adult patients, especially those severely immunocompromised, in association with a reactivation of a herpes virus infection. We present a 4 years old patient with high risk acute leukemia, whom during a course of intense chemotherapy acquired chickenpox with visceral involvement that affected the retina, causing unilateral blindness. Varicella-zoster virus was detected by PCR in the vitreous humor, in spite of previous acyclovir treatment. The contralateral vision remained undamaged.
Torres T
Juan P
JP
Departamento de Pediatría Oriente, Universidad de Chile, Santiago, Chile. jptorres@med.uchile.cl
Concha V
Emma
E
López G
Juan P
JP
Cofre G
José
J
D000998:Antiviral Agents / Q000627:therapeutic use; D002644:Chickenpox / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D002675:Child, Preschool; D006801:Humans; D016867:Immunocompromised Host; D008297:Male; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000188:drug therapy*; D015882:Retinal Necrosis Syndrome, Acute / Q000175:diagnosis / Q000188:drug therapy / Q000821:virology*
D000998:Antiviral Agents