title: Value of elastin staining in the assessment of peritoneal implants associated with ovarian serous borderline tumours.
abstract: OBJECTIVE
  To determine whether elastin stains aid in classifying peritoneal implants associated with ovarian serous borderline tumours (SBT).
  
  
  RESULTS
  The study group comprised 80 implants (nine invasive and 71 non-invasive) from 28 patients with ovarian SBT. Elastin stains were performed using histochemical and immunohistochemical methods to demonstrate the peritoneal elastic lamina (PEL), and evaluated with regard to assessment of the subtype of implant. The elastin stains demonstrated the PEL in most anatomical sites other than the omentum and the bladder and were considered helpful in 44/80 (55%) cases. The stains were most useful in the assessment of poorly oriented or traumatized biopsy specimens and in confirming the superficial distribution of non-invasive implants. The staining was non-contributory in most of the remaining biopsies, because the PEL was not identified.
  
  
  CONCLUSIONS
  Demonstration of the PEL using elastin stains can be useful in the subclassification of implants associated with ovarian SBT and is of most value in confirming the superficial distribution of non-invasive lesions. However, evaluation is limited by the absence of a defined elastic layer in a proportion of biopsy specimens, possibly reflecting their superficial location, as well as absence of a distinct PEL in sites such as the omentum.
authors.affiliation: Department of Pathology, King Edward Memorial Hospital, Perth, Western Australia, Australia. colin.stewart@health.wa.gov.au
authors.forename: C J R
authors.initials: CJ
authors.lastname: Stewart
authors.forename: B A
authors.initials: BA
authors.lastname: Brennan
authors.forename: M L
authors.initials: ML
authors.lastname: Crook
authors.forename: P
authors.initials: P
authors.lastname: Russell
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D018284:Cystadenocarcinoma, Serous / Q000378:metabolism / Q000473:pathology*; D004549:Elastin / Q000032:analysis*; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000378:metabolism / Q000473:pathology*; D010534:Peritoneal Neoplasms / Q000175:diagnosis / Q000378:metabolism / Q000556:secondary; D010537:Peritoneum / Q000737:chemistry / Q000473:pathology*; D011237:Predictive Value of Tests
chemical_list: D004549:Elastin