Sentinel lymph node biopsy for gastrointestinal cancers.
Sentinel lymph node biopsy (SLNB) in gastrointestinal-(GI)-tract cancer is not yet of clinical relevance. Nevertheless, the results in the upper GI-tract promise to be helpful to individualize the indication for surgical therapy. SLNB in colon cancer still fails to show high validity to predict the nodal status, but may be helpful to clarify the prognostic role of micrometastases/isolated tumor cells. In anal cancer SLNB is able to guide the indication for groin irradiation.
Bembenek
A
A
Department of Surgery and Surgical Oncology, Robert-Rössle-Klinik, Charité Universitätsmedizin Berlin, Campus Buch, Lindenberger, Berlin, Germany.
Gretschel
S
S
Schlag
P M
PM
D000230:Adenocarcinoma / Q000473:pathology; D001005:Anus Neoplasms / Q000473:pathology; D003110:Colonic Neoplasms / Q000473:pathology; D004938:Esophageal Neoplasms / Q000473:pathology; D005770:Gastrointestinal Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008198:Lymph Nodes / Q000000981:diagnostic imaging* / Q000473:pathology*; D008207:Lymphatic Metastasis; D011237:Predictive Value of Tests; D011379:Prognosis; D011877:Radionuclide Imaging; D012004:Rectal Neoplasms / Q000473:pathology; D012680:Sensitivity and Specificity; D021701:Sentinel Lymph Node Biopsy / Q000379:methods*; D013274:Stomach Neoplasms / Q000473:pathology