[Influence of compatibility on content of berberine in Maxingganshi decoction].
OBJECTIVE
To set up the quantitative method of herberine in decoctions prepared from various combinations of Maxingganshi decotion by HPLC and to determine the change of general contents in different decoction.


METHODS
The study was designed by L8 (2(7)) orthogonal and to determine the change of general contents in different decoction by HPLC.


RESULTS
In full formula remove Glycyrrhiza uralensis group, the contents of L-ephedrine, d-pseudephedrine and the amygdaloside cut down significantly. In full formula remove armeniacae semen group, the content of glycyrrhetic acid cut down significantly. Four chemical composition in full formula group had higher contents.


CONCLUSIONS
Armeniacae semen can decrease the content of L-ephedrine, D-pseudephedrine. Glycyrrhiza uralensis can help decoctum amygdaloside and armeniacae semen can help decoctum glycyrrhizic acid.
Wang
Wei-Guang
WG
Guangdong Provincial Health Care Hospital for Women and Children, Guangzhou 510010, China.
Shi
Xu-Guang
XG
Zhai
Li-Xiang
LX
Wang
Pei-Jian
PJ
Peng
Xiu-Feng
XF
Xu
Yu-Ying
YY
D000678:Amygdalin / Q000032:analysis / Q000302:isolation & purification; D001599:Berberine / Q000032:analysis* / Q000302:isolation & purification; D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal / Q000032:analysis* / Q000302:isolation & purification; D004809:Ephedrine / Q000032:analysis / Q000302:isolation & purification; D029882:Glycyrrhiza uralensis / Q000737:chemistry; D019695:Glycyrrhizic Acid / Q000032:analysis / Q000302:isolation & purification; D010946:Plants, Medicinal / Q000737:chemistry*; D027861:Prunus / Q000737:chemistry; D015203:Reproducibility of Results; D013678:Technology, Pharmaceutical / Q000379:methods
D004338:Drug Combinations; D004365:Drugs, Chinese Herbal; D001599:Berberine; D000678:Amygdalin; D019695:Glycyrrhizic Acid; D004809:Ephedrine