title: [Optimizing the best extraction condition of semi-bionic extraction for licorice by unifrom design].
abstract: OBJECTIVE
  To optimize the best extraction condition of semi-bionic extraction for licorice.
  
  
  METHODS
  The best extraction condition of the semi-bionic extraction for licorice by uniform design was optimized with glycyrrhizic acid, total flavonoids, total polysaccharides, total HPLC integrate area and dried extract weight as the indexes.
  
  
  RESULTS
  The optimized technologic condition: The pH values of the water for the 1st, 2nd, and 3rd decoctions were in order of 5.88, 7.50, and 8.90, and the total extraction time was 3.93 h.
  
  
  CONCLUSIONS
  According to industry production condition, the best SBE technologic condition is: The pH values of the water for the 3 decoctions are in order of 6.0, 7.5, and 9.0, and the extraction time are 2h, 1h, and 1h, respectively.
authors.affiliation: 401th Hospital of PLA, Qingdao 266071, China.
authors.forename: Yan-Qin
authors.initials: YQ
authors.lastname: Cheng
authors.forename: Xiu-Mei
authors.initials: XM
authors.lastname: Sun
authors.forename: Zhao-Wang
authors.initials: ZW
authors.lastname: Zhang
authors.forename: Jian-Guo
authors.initials: JG
authors.lastname: Hui
mesh_terms: D004365:Drugs, Chinese Herbal / Q000737:chemistry* / Q000302:isolation & purification; D005419:Flavonoids / Q000032:analysis*; D006035:Glycyrrhiza / Q000737:chemistry*; D019695:Glycyrrhizic Acid / Q000032:analysis*; D006358:Hot Temperature; D006863:Hydrogen-Ion Concentration; D018517:Plant Roots / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry; D011134:Polysaccharides / Q000032:analysis; D027343:Rhizome / Q000737:chemistry; D013678:Technology, Pharmaceutical / Q000379:methods*; D013997:Time Factors
chemical_list: D004365:Drugs, Chinese Herbal; D005419:Flavonoids; D011134:Polysaccharides; D019695:Glycyrrhizic Acid