title: Severe hypermagnesemia as a result of excessive cathartic ingestion in a child without renal failure.
abstract: A 14-year-old girl was referred to our hospital with lethargy and hypotension and was found to have a serum magnesium level of 14.9 mg/dL after having received an magnesium hydroxide (Magnesie Calcinee) for 7 days because of constipation. She was lethargic, her blood pressure was 70/40 mm Hg, and electrocardiogram revealed prolonged corrected QT interval and first-degree atrioventricular block. She has no renal dysfunction. Emergency hemodialysis after her condition ameliorated, her serum magnesium levels returned to normal. The present case suggests that massive oral magnesium ingestion with severe constipation and ileus may result severe hypermagnesemia without renal dysfunction.
authors.affiliation: Department of Pediatrics, Karaelmas University Faculty of Medicine, Zonguldak, Turkey. ebkut@yahoo.com
authors.forename: Ebru
authors.initials: E
authors.lastname: Kutsal
authors.forename: Cumhur
authors.initials: C
authors.lastname: Aydemir
authors.forename: Nilufer
authors.initials: N
authors.lastname: Eldes
authors.forename: Fatma
authors.initials: F
authors.lastname: Demirel
authors.forename: Recep
authors.initials: R
authors.lastname: Polat
authors.forename: Ozan
authors.initials: O
authors.lastname: Taspnar
authors.forename: Eyup
authors.initials: E
authors.lastname: Kulah
mesh_terms: D000293:Adolescent; D002400:Cathartics / Q000506:poisoning*; D003248:Constipation / Q000188:drug therapy; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008274:Magnesium / Q000097:blood*; D008276:Magnesium Hydroxide / Q000506:poisoning*; D011041:Poisoning / Q000097:blood / Q000175:diagnosis / Q000628:therapy; D051437:Renal Insufficiency / Q000175:diagnosis; D016896:Treatment Outcome
chemical_list: D002400:Cathartics; D008274:Magnesium; D008276:Magnesium Hydroxide