Juvenile idiopathic arthritis: some progress but still many uncertainties.
(1) Juvenile idiopathic arthritis is a chronic inflammatory rheumatic disorder of unknown cause. Spontaneous remission is frequent. Between 10% and 20% of patients have ocular involvement. (2) Nonsteroidal antiinflammatory drugs and physiotherapy are the cornerstones of patient management. Intra-articular steroid injection generally provides several months of relief. The place of immunosuppressants is difficult to ascertain, given their uncertain benefits and established long-term risks in children. There is no curative treatment at present.
D000293:Adolescent; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects / Q000627:therapeutic use; D000911:Antibodies, Monoclonal / Q000009:adverse effects / Q000627:therapeutic use; D018501:Antirheumatic Agents / Q000008:administration & dosage / Q000009:adverse effects; D001171:Arthritis, Juvenile / Q000150:complications / Q000188:drug therapy* / Q000276:immunology; D002648:Child; D005602:France; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects / Q000627:therapeutic use; D009902:Optic Neuritis / Q000139:chemically induced; D026741:Physical Therapy Modalities; D015995:Prevalence
D000894:Anti-Inflammatory Agents, Non-Steroidal; D000911:Antibodies, Monoclonal; D018501:Antirheumatic Agents; D007166:Immunosuppressive Agents