title: Syringocystadenocarcinoma papilliferum: a case report.
abstract: Syringocystadenocarcinoma papilliferum (SCACP) is a rare form of adenocarcinoma of the skin. This is the malignant counterpart of syringocystadenoma papilliferum (SCAP) and usually develops on the scalp in a long-standing lesion identified clinically as SCAP. We describe a 65-yr-old Korean man with a nodule on the right supra-pubic area with a 2-yr duration. Histologically this tumor had a similar overall configuration as in SCAP, but the tumor was asymmetric and poorly circumscribed, extending into the deep dermis and showed cytologic atypia. The tumor cells showed positive reaction to GCDFP-15, but negative reaction to CEA and HMFG-1. We established the diagnosis of SCACP in the patient, and a wide excision was performed to remove the tumor. The patient has been well without relapse or metastasis for 2 yr.
authors.affiliation: Department of Dermatology, College of Medicine, Yeungnam University, Daegu, Korea.
authors.forename: So Hyun
authors.initials: SH
authors.lastname: Park
authors.forename: Young Min
authors.initials: YM
authors.lastname: Shin
authors.forename: Dong Hoon
authors.initials: DH
authors.lastname: Shin
authors.forename: Jong Soo
authors.initials: JS
authors.lastname: Choi
authors.forename: Ki Hong
authors.initials: KH
authors.lastname: Kim
mesh_terms: D000368:Aged; D002352:Carrier Proteins / Q000032:analysis; D018283:Cystadenocarcinoma, Papillary / Q000378:metabolism / Q000473:pathology*; D006023:Glycoproteins / Q000032:analysis; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D026901:Membrane Transport Proteins; D013544:Sweat Gland Neoplasms / Q000378:metabolism / Q000473:pathology*; D018252:Syringoma / Q000378:metabolism / Q000473:pathology*
chemical_list: D002352:Carrier Proteins; D006023:Glycoproteins; D026901:Membrane Transport Proteins; C488892:PIP protein, human