title: A cosmetic ingredient innovation for the stabilization and delivery of volatile fluoroether with cosmetic applications.
abstract: Initially this work attempts to support, evaluate and identify the stabilization and release mechanism of volatile fluoroether (Cosmetic Fluid CF-61) in a self-assembling nanostructure in an external water phase (Phoenomulse CE-1) through evaporation rate analysis. The release mechanism is hypothesized to be a result of a dehydration process, a decrease in water efficiency due to evaporation of external water at the liquid-air interface, which results in destabilization of the nanostructure. This work further attempts to quantify the release mechanism of the same volatile fluoroether (Cosmetic Fluid CF-61) from the nanostructure in cosmetic formulations through a newly developed in vitro test method which measures initial foam generation rate. Finally, this work demonstrates the application of these newly developed test methods as a useful tool for product development, formulation navigation, and performance optimization.
authors.affiliation: Departments of Applications & Claims Support, Phoenix Chemical Inc., 60 Fourth Street, Somerville, NJ 08876, USA.
authors.forename: Steve
authors.initials: S
authors.lastname: Cochran
authors.forename: Tim
authors.initials: T
authors.lastname: Brockman
mesh_terms: D004355:Drug Stability; D004987:Ethers / Q000737:chemistry*; D005960:Glucosides / Q000737:chemistry*; D006203:Hair Preparations / Q000737:chemistry*; D006801:Humans; D006845:Hydrocarbons, Fluorinated / Q000737:chemistry; D013499:Surface Properties
chemical_list: D004987:Ethers; D005960:Glucosides; D006203:Hair Preparations; D006845:Hydrocarbons, Fluorinated; C504907:decyl glucoside