The alphabeta T cell repertoire comes into focus.
The size of the lymphocyte repertoire is of great interest, but direct information has been elusive. Moon et al. (2007) report the enumeration and isolation of naive CD4(+) T cells and show their numbers could predict the size and diversity of the primary immune response.
Davis
Mark M
MM
The Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, CA 94305, USA. mmdavis@stanford.edu
D000818:Animals; D008024:Ligands; D051379:Mice; D016693:Receptors, Antigen, T-Cell, alpha-beta / Q000032:analysis / Q000502:physiology*; D013601:T-Lymphocytes / Q000276:immunology*
D008024:Ligands; D016693:Receptors, Antigen, T-Cell, alpha-beta