title: Factors affecting performance of usual activities during radiation therapy.
abstract: OBJECTIVE
  To examine factors that might affect patients' ability to perform their usual activities during radiation therapy.
  
  
  METHODS
  Prospective, longitudinal design.
  
  
  METHODS
  A community hospital radiation oncology department.
  
  
  METHODS
  77 patients receiving radiation therapy for curative or adjuvant intent.
  
  
  METHODS
  The role function mode of the Roy Adaptation Model guided the study. Participants rated the extent to which they were performing their usual activities on a scale of 0 (not at all) to 10 (all the time). Data were collected at baseline prior to starting radiation, weekly during treatment, and one month post-treatment. Cross-sectional and longitudinal regression analyses were used to capture changes in performance of usual activities over time.
  
  
  METHODS
  Performance of usual activities, Karnofsky Performance Status (KPS), fatigue, and side effects.
  
  
  RESULTS
  Participants maintained relatively high performance status throughout the course of treatment. The ability to perform usual activities decreased significantly from baseline to the end of treatment. Ability to perform usual activities was highly negatively correlated with fatigue and side effects. Work, sick-leave benefits, living situation, fatigue, KPS, and comorbidities were associated with ability to perform usual activities along the trajectory of radiation therapy.
  
  
  CONCLUSIONS
  Fatigue and side effects of treatment negatively affected patients' ability to carry out their usual activities during radiation therapy.
  
  
  CONCLUSIONS
  Management of side effects of treatment, including fatigue, and supporting patients' need to work or not work during treatment may help patients continue to perform activities that are important to them during radiation therapy.
authors.affiliation: School of Nursing, University of Maine, Orono, USA. patricia.poirier@umit.maine.edu
authors.forename: Patricia
authors.initials: P
authors.lastname: Poirier
mesh_terms: D000203:Activities of Daily Living; D000328:Adult; D000368:Aged; D015984:Causality; D003430:Cross-Sectional Studies; D004651:Employment / Q000706:statistics & numerical data; D005221:Fatigue / Q000453:epidemiology; D005260:Female; D006801:Humans; D016014:Linear Models; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D016294:Models, Nursing; D015999:Multivariate Analysis; D009369:Neoplasms / Q000453:epidemiology / Q000532:radiotherapy*; D011446:Prospective Studies; D012380:Role; D018582:Sick Leave / Q000706:statistics & numerical data; D012944:Social Support; D013647:Task Performance and Analysis; D014481:United States / Q000453:epidemiology