Collagen synthesis by cells synchronously replicating DNA.
Replication and the performance of a differentiated function have been considered antagonistic processes. When cells in culture are partially tially synchronized with 5-fluoro-2'-deoxyuridine (FUdR), the synthesis of the specialized protein (collagen) is not reduced during chromosomal replication (S period). Collagen synthesis varies with general protein synthesis through the S period.
Davies
L M
LM
Priest
J H
JH
Priest
R E
RE