title: Intracellular cytoskeletal elements and cytoskeletons in bacteria.
abstract: Within a short period of time after the discovery of bacterial cytoskletons, major progress had been made in areas such as general spatial layout of cytoskeletons, their involvement in a variety of cellfunctions (shape control, cell division, chromosome segregation, cell motility). This progress was achieved by application of advanced investigation techniques. Homologs of eukaryotic actin, tubulin, and intermediate filaments were found in bacteria; cytoskeletal proteins not closely or not at all related to any of these major cytoskeletal proteins were discovered in a number of bacteria such as Mycoplasmas, Spiroplasmas, Spirochetes, Treponema, Caulobacter. A structural role for bacterial elongation factor Tu was indicated. On the basis of this new thinking, new approaches in biotechnology and new drugs are on the way.
authors.affiliation: Ain Shams University, Faculty of Agriculture, Central Laboratory, Electron Microscope Division, Cairo, Egypt. madkour@gmx.net
authors.forename: Mohamed H F
authors.initials: MH
authors.lastname: Madkour
authors.forename: Frank
authors.initials: F
authors.lastname: Mayer
mesh_terms: D001419:Bacteria / Q000235:genetics / Q000378:metabolism / Q000648:ultrastructure; D002455:Cell Division / Q000235:genetics / Q000502:physiology; D003598:Cytoskeletal Proteins / Q000235:genetics / Q000378:metabolism; D003599:Cytoskeleton / Q000235:genetics / Q000378:metabolism / Q000502:physiology / Q000648:ultrastructure
chemical_list: D003598:Cytoskeletal Proteins