title: AIDS-associated central nervous system cryptococcosis: a Brazilian case study.
abstract: In recent years the effect of HAART in patients with AIDS has been great at decreasing the incidence of opportunistic infections. Nonetheless, patients with AIDS living in developing countries still present with severe central nervous system cryptococcosis, with high mortality rates. The study of the clinical-epidemiological-laboratory aspects of the patients treated before the HAART era might be useful in an assessment of the impact of these drugs in the prognosis of cases.
authors.affiliation: Instituto de Infectologia Emilio Ribas, Brazil.
authors.forename: Mara C S M
authors.initials: MC
authors.lastname: Pappalardo
authors.forename: Regina Célia
authors.initials: RC
authors.lastname: Paschoal
authors.forename: Marcia S C
authors.initials: MS
authors.lastname: Melhem
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000453:epidemiology* / Q000401:mortality / Q000517:prevention & control; D000935:Antifungal Agents / Q000627:therapeutic use; D023241:Antiretroviral Therapy, Highly Active; D001938:Brazil / Q000453:epidemiology; D002494:Central Nervous System Infections / Q000453:epidemiology* / Q000401:mortality / Q000517:prevention & control; D003453:Cryptococcosis / Q000453:epidemiology* / Q000401:mortality / Q000517:prevention & control; D003455:Cryptococcus neoformans / Q000302:isolation & purification; D005260:Female; D006801:Humans; D008297:Male; D017211:Treatment Failure
chemical_list: D000935:Antifungal Agents