[Chondroblastoma].
Chondroblastom, benign cartilage tissue neoplasm, accounts for 1% of all bone tumors. It is encountered in any skeletal bones mainly in persons aged 10 and 25 years. Morphologically, it is represented as large homogenous cells--well-defined oval polygonal chondroblasts with a fine eosinophilic cytoplasm, and a round-to-oval nucleus. Cartilaginous portions of chondroblastoma form lobular structures. The tumor always comprises single-to-multiple multinucleate giant cells. The pathognomonic sign of chondroblastoma is intercellular reticular basophilically stained calcifications as a mesh. Mitotic cells, rather than abnormal ones, are present. There are cases of primary malignant chondroblastomas.
Bulycheva
I V
IV
Semenov
L A
LA
Makhson
A N
AN
Zhukov
A G
AG
D000328:Adult; D001859:Bone Neoplasms / Q000000981:diagnostic imaging* / Q000235:genetics / Q000628:therapy*; D002648:Child; D002804:Chondroblastoma / Q000000981:diagnostic imaging* / Q000235:genetics / Q000628:therapy*; D006801:Humans; D011379:Prognosis; D011859:Radiography