title: Ecdysone analog: conversion to alpha ecdysone and 20-hydroxyecdysone by an insect.
abstract: The tritium-labeled synthetic ecdysone analog Delta(7)-5beta-cholestene-2beta,-3beta,14alpha-triol-6-one terminated diapause when injected into diapausing tobacco hornworm pupae and was converted into tritium-labeled alpha-ecdysone and tritium-labeled 20-hydroxyecdysone. About half of the crystalline alpha-ecdysone and 20-hydroxyecdysone isolated from the tobacco hornworms 7(1/2) to 8(1/2) days after injection was derived from endogenous steroid precursors and half from the transformation of the synthetic ecdysone analog.
authors.forename: J N
authors.initials: JN
authors.lastname: Kaplanis
authors.forename: W E
authors.initials: WE
authors.lastname: Robbins
authors.forename: M J
authors.initials: MJ
authors.lastname: Thompson
authors.forename: A H
authors.initials: AH
authors.lastname: Baumhover