title: [Automobile tyre colloidal particle induced allergic damage of respiratory system in traffic policemen and its allergenicity].
abstract: OBJECTIVE
  To explore the damage of respiratory system in the traffic policemen induced by automobile tyre colloidal particle and its allergenicity.
  
  
  METHODS
  The respiratory system symptoms in 445 traffic policemen working outside their offices and 243 controls were investigated and their pulmonary ventilation function index such as FVC, FEV(1.0), MMF and V(50) were determined. The specific IgE antibody of automobile tyre colloidal particle of their serum was determined and the skin-prick test of automobile tyre colloidal particle antigen was performed. Sixty-six traffic policemen working outside their offices and 5 controls with the positive of IgE antibody among them were detected by nasal mucosa provocation test. Sixty-six traffic policemen working outside their offices with the positive of IgE antibody were determined by Terbutaline inhalation test.
  
  
  RESULTS
  The positive rate of respiratory system symptoms of traffic policemen such as cough, stethocatharsis, short breath, nasal obstruction, sneeze and nose running was 38.02%, 27.03%, 20.00%, 23.08%, 27.47%, 32.09% and 34.95% respectively and significantly higher than those of the control with significant difference (P < 0.01) or (P < 0.05). The positive rate of specific IgE antibody of automobile tyre colloidal particle, skin- prick test and nasal mucosa provocation test was 14.51%, 23.73% and 54.55% respectively with significant difference (P < 0.01) and (P < 0.05). The percentage, the actual figure compared with the prediction figure, of the index of pulmonary ventilation function (FVC, FEV(1.0) MMF and V(50)) of traffic policemen were significantly lower than those of the control. Terbutaline inhalation test in 66 positive subjects of specific IgE antibody of automobile tyre colloidal particle was positive in 44 subjects, accounting for 9.67% in all policemen investigated.
  
  
  CONCLUSIONS
  The automobile tyre colloidal particle is one of etiological factors that induce pulmonary ventilation function damage and could result in allergic asthma of traffic police.
authors.affiliation: Department of Preventive Medicine, Medical College, Xiamen University, Xiamen Fujian 361005, China.
authors.forename: Yong-xing
authors.initials: YX
authors.lastname: Zhang
authors.forename: Qing-yu
authors.initials: QY
authors.lastname: Wei
authors.forename: Juan
authors.initials: J
authors.lastname: Wang
authors.forename: Ting-hui
authors.initials: TH
authors.lastname: Qiao
authors.forename: Hong-bing
authors.initials: HB
authors.lastname: Bai
authors.forename: Li-na
authors.initials: LN
authors.lastname: Cai
mesh_terms: D000328:Adult; D000485:Allergens / Q000032:analysis; D001336:Automobiles; D006801:Humans; D007073:Immunoglobulin E / Q000097:blood; D008297:Male; D008875:Middle Aged; D016273:Occupational Exposure / Q000009:adverse effects*; D016495:Police; D012137:Respiratory System / Q000187:drug effects*; D012408:Rubber / Q000009:adverse effects*; D055815:Young Adult
chemical_list: D000485:Allergens; D007073:Immunoglobulin E; D012408:Rubber