[Monomers optimization and properties evaluation of quercetin-imprinted polymer and its application to thin layer chromatography stationary phase].
The quercetin-molecularly imprinted polymers with specific affinity and selectivity were prepared by using methacrylic acid (MAA), acrylamide (AM), N,N-(diethylamino) ethyl methacrylate and 2-vinylpyridine as functional monomers, respectively. The adsorption properties for template were studied by equilibrium binding experiments. The results showed 2-VP and DEAEM based on ionic interaction with quercetin possessed better imprinting effects. Using the quercetin-imprinted polymers as thin layer chromatographic stationary could successfully separate the template from the other structurally related compounds. In addition, the influence on adsorption effect about the particle size and repeating times of MIP were investigated.
He
Jian-Feng
JF
College of Chinese Traditional Medicine, Guangzhou University of Traditional Chinese Medicine, Guangzhou 510006, China. syrinx@gzhtcm.edu.cn
Deng
Qin-Ying
QY
D000327:Adsorption; D002855:Chromatography, Thin Layer / Q000295:instrumentation / Q000379:methods*; D003432:Cross-Linking Reagents / Q000737:chemistry; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification*; D054802:Molecular Imprinting; D011108:Polymers / Q000737:chemistry* / Q000302:isolation & purification; D011794:Quercetin / Q000737:chemistry* / Q000302:isolation & purification; D015203:Reproducibility of Results; D013678:Technology, Pharmaceutical / Q000295:instrumentation / Q000379:methods
D003432:Cross-Linking Reagents; D004365:Drugs, Chinese Herbal; D011108:Polymers; D011794:Quercetin