Rare association of a patient with Alagille syndrome and mitral valve regurgitation.
A 9-year-old patient with known Alagille syndrome presented to our institution with progressive mitral valve regurgitation due to prolapse of the posterior valve leaflet. She underwent successful mitral valve replacement with a mechanical prosthesis 4 years after the initial diagnosis. To the best of our knowledge, an association between mitral valve regurgitation and Alagille syndrome has not been previously described.
Kelpis
T G
TG
Yorkshire Paediatric Cardiothoracic Centre, Leeds General Infirmary, Leeds, UK. tkelpis@yahoo.com
Taliotis
D M
DM
Weerasena
N A
NA
D016738:Alagille Syndrome / Q000150:complications*; D002648:Child; D017548:Echocardiography, Transesophageal; D005260:Female; D005500:Follow-Up Studies; D019918:Heart Valve Prosthesis Implantation / Q000379:methods; D006801:Humans; D008944:Mitral Valve Insufficiency / Q000150:complications* / Q000000981:diagnostic imaging / Q000601:surgery