[Gastric tumor of complex structure].
The paper describes a case of gastric tumor comprising moderately differentiated adenocarcinoma and atypical carcinoid with metastases of both types of tumor cells in the lymph nodes. Electron microscopic and immunohistochemical studies of primary gastric tumor and lymph nodal metastases confirmed the presence of both differentiation types within one space-occupying lesion: such as goblet (mucin-producing) and neuroendocrine cells. The differentiation varied in different fields of vision with a preponderance of low-grade ultrastructural differentiation cells. Thus, electron microscopic and immunohistochemical studies of tumors not only verify their diagnosis and make a histogenetic differential diagnosis of various neoplasms, but also define the degree of their maturation.
Smirnova
E A
EA
Gurevich
L E
LE
Polikarpova
S B
SB
Kokosadze
N V
NV
D000230:Adenocarcinoma / Q000175:diagnosis* / Q000648:ultrastructure; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008207:Lymphatic Metastasis; D008854:Microscopy, Electron; D008875:Middle Aged; D013274:Stomach Neoplasms / Q000175:diagnosis* / Q000648:ultrastructure