[Correction of the endothelial function damaged by gamma-irradiation with free and liposomal quercetin].
It has been investigation the action of solubil quercetin (corvitin) and quercetin filled liposomes (lipoflavon) on endothelium--dependent r-irradiated isolated rats aortic rings relaxations to acetylcholine. It has been showed, that corvitin addition directly to the buffer solution (0.1 mg/ml) increase endothelium--dependent vascular responses to acetylcholine on 35%, lipoflavon addition--on 25%.
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D000818:Animals; D001013:Aorta, Thoracic / Q000187:drug effects / Q000528:radiation effects; D004730:Endothelium, Vascular / Q000187:drug effects / Q000528:radiation effects; D005720:Gamma Rays; D008081:Liposomes; D011794:Quercetin / Q000008:administration & dosage / Q000494:pharmacology*; D011833:Radiation Injuries, Experimental / Q000503:physiopathology*; D051381:Rats; D014664:Vasodilation / Q000187:drug effects / Q000528:radiation effects; D014665:Vasodilator Agents / Q000008:administration & dosage / Q000494:pharmacology*
D008081:Liposomes; D014665:Vasodilator Agents; D011794:Quercetin