title: [Recurrent bilateral shoulder hand syndrome induced by phenobarbital].
abstract: Algodystrophy syndrome is characterized by pain, vasomotor disorders and/or trophic skin changes, without laboratory signs of inflammation. Among the etiological factors of this syndrome (trauma, cerebrovascular accident, diabetes mellitus...), iatrogenic ones including phenobarbital can be observed. We report a case of phenobarbital induced recurrent bilateral shoulder-hand syndrome in a 67 years old women with hypertension, diabetes, and history of epileptic crisis following ischemic cerebrovascular accidents. The patient recovered after barbiturate withdrawal and treatment with calcitonin. It's necessary to diagnose promptly shoulder-hand syndrome of iatrogenic cause in order to withdraw definitively the responsible drug, to start an effective therapy, at this stage, on pain and bone demineralization and to prevent severe sequels.
authors.affiliation: Centre National de Pharmacovigilance, Hôpital Razi, Tunis.
authors.forename: S Imène
authors.initials: SI
authors.lastname: Hamza
authors.forename: Zohra
authors.initials: Z
authors.lastname: Hassen
authors.forename: M Hédi
authors.initials: MH
authors.lastname: Loueslati
authors.forename: M Néjib
authors.initials: MN
authors.lastname: Toghourti
authors.forename: Chelbi
authors.initials: C
authors.lastname: Belkahia
authors.forename: Mohsen
authors.initials: M
authors.lastname: Hamza
mesh_terms: D000368:Aged; D000927:Anticonvulsants / Q000009:adverse effects*; D005260:Female; D006801:Humans; D010634:Phenobarbital / Q000009:adverse effects*; D012008:Recurrence; D012019:Reflex Sympathetic Dystrophy / Q000139:chemically induced*
chemical_list: D000927:Anticonvulsants; D010634:Phenobarbital