[Diffusion weighted imaging: its diagnostic and differential value for prostate cancer].
OBJECTIVE
To explore the diagnostic and differential value of diffusion weighted imaging (DWI) for prostate cancer.


METHODS
Included in the study were 50 patients with prostatic diseases, including 19 cases of prostate cancer (PCa) and 31 cases of benign prostatic hyperplasia (BPH), and another 16 healthy volunteers were recruited as controls. All underwent DWI sequence on a 1.5T superconducting MRI system with an endorectal coil. The results from DWIs and apparent diffusion coefficient (ADC) maps were treated statistically.


RESULTS
The mean ADC value of the prostatic peripheral zone and the prostatic central gland of the 16 healthy volunteers were (170.23 +/- 37.39) x 10(-5) mm2/s and (127.84 +/- 17.93) x 10(-5) mm2/s, while those of the 31 BPH cases and 19 PCa cases were (175.21 +/- 64.86) x 10(-5) mm2/s and (104.23 +/- 26.15) x 10(-5) mm2/s, respectively. There were significant differences in the tissue types between any two groups after the treatment of one-way ANOVA, except between the groups of the peripheral zone and. BPH.


CONCLUSIONS
PCa shows specific DWI features that could be distinguished from those of the normal prostatic tissues and BPH. Therefore, DWI has an important clinical application value in the diagnosis and differentiation of PCa.
Shi
Hao
H
Shandong Medical Imaging Research Institute, Jinan, Shandong 250021, China. hansenschie@163.com
Ding
Hong-Yu
HY
D000328:Adult; D000368:Aged; D003937:Diagnosis, Differential; D038524:Diffusion Magnetic Resonance Imaging / Q000295:instrumentation / Q000379:methods*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011467:Prostate / Q000473:pathology*; D011471:Prostatic Neoplasms / Q000175:diagnosis*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity