title: A cocaine-associated quadriplegia and motor aphasia after first use of cocaine.
abstract: A 31-year-old female who have snorted one "line" of cocaine hydrochloride (approximately 35 mg), for the first time in her life, was admitted to the hospital because of acute onset of right hemiplegia and left hemiparesis evolving into quadriplegia. Motor aphasia, right eye-ball divergent strabismus and right mouth recess lowering were also observed.
  
  
  CONCLUSIONS
  A first time mucosal administration of cocaine hydrochloride even in low dose can cause severe neurological complications like quadriplegia and aphasia. Cocaine-associated stroke can be a diagnostic problem in the emergency room. Unconscious patients or those with acute onset of neurological disorders can form a real diagnostic challenge, especially when there is no evidence of previous drug taking.
authors.affiliation: Department of Internal Medicine, Geriatry and Clinical Toxicology, Medical University of Gdańsk. jsanand@amg.gda.pl
authors.forename: Jacek
authors.initials: J
authors.lastname: Sein Anand
authors.forename: Zygmunt
authors.initials: Z
authors.lastname: Chodorowski
authors.forename: Marek
authors.initials: M
authors.lastname: Wiśniewski
authors.forename: Agnieszka
authors.initials: A
authors.lastname: Gólska
mesh_terms: D000328:Adult; D001039:Aphasia, Broca / Q000139:chemically induced* / Q000534:rehabilitation / Q000628:therapy; D002545:Brain Ischemia / Q000139:chemically induced*; D019970:Cocaine-Related Disorders / Q000209:etiology* / Q000534:rehabilitation / Q000628:therapy; D016578:Crack Cocaine / Q000008:administration & dosage* / Q000506:poisoning*; D005260:Female; D006801:Humans; D010291:Paresis / Q000139:chemically induced / Q000534:rehabilitation / Q000628:therapy; D011782:Quadriplegia / Q000139:chemically induced* / Q000534:rehabilitation / Q000628:therapy; D020521:Stroke / Q000139:chemically induced* / Q000150:complications; D016896:Treatment Outcome
chemical_list: D016578:Crack Cocaine