title: What's eating you? Bees, Part 2: Venom immunotherapy and mastocytosis.
abstract: Bee stings are common in the United States. In part 1 of this series, we reviewed the characteristics of bumblebees, honeybees, and Africanized honeybees; the types and pathophysiology of sting reactions; and the medical management and prevention of bee stings. In this article, we review the concepts and practice of venom immunotherapy. We further discuss the diagnosis of systemic mastocytosis, initially presenting as anaphylaxis, and the efficacy of immunotherapy in patients with mastocytosis.
authors.affiliation: Department of Allergy and Immunology, Walter Reed Army Medical Center, Washington, DC, USA. felisa.lewis@na.amedd.army.mil
authors.forename: Felisa S
authors.initials: FS
authors.lastname: Lewis
authors.forename: Laurie J
authors.initials: LJ
authors.lastname: Smith
mesh_terms: D000465:Algorithms; D000707:Anaphylaxis / Q000276:immunology / Q000517:prevention & control*; D000818:Animals; D001514:Bee Venoms / Q000037:antagonists & inhibitors*; D001516:Bees; D006801:Humans; D007167:Immunotherapy; D007299:Insect Bites and Stings / Q000150:complications / Q000628:therapy*; D034721:Mastocytosis, Systemic / Q000276:immunology / Q000517:prevention & control*; D014612:Vaccines / Q000627:therapeutic use*
chemical_list: D001514:Bee Venoms; D014612:Vaccines