title: Rare association of a patient with Alagille syndrome and mitral valve regurgitation.
abstract: A 9-year-old patient with known Alagille syndrome presented to our institution with progressive mitral valve regurgitation due to prolapse of the posterior valve leaflet. She underwent successful mitral valve replacement with a mechanical prosthesis 4 years after the initial diagnosis. To the best of our knowledge, an association between mitral valve regurgitation and Alagille syndrome has not been previously described.
authors.affiliation: Yorkshire Paediatric Cardiothoracic Centre, Leeds General Infirmary, Leeds, UK. tkelpis@yahoo.com
authors.forename: T G
authors.initials: TG
authors.lastname: Kelpis
authors.forename: D M
authors.initials: DM
authors.lastname: Taliotis
authors.forename: N A
authors.initials: NA
authors.lastname: Weerasena
mesh_terms: D016738:Alagille Syndrome / Q000150:complications*; D002648:Child; D017548:Echocardiography, Transesophageal; D005260:Female; D005500:Follow-Up Studies; D019918:Heart Valve Prosthesis Implantation / Q000379:methods; D006801:Humans; D008944:Mitral Valve Insufficiency / Q000150:complications* / Q000000981:diagnostic imaging / Q000601:surgery