title: The history of the development of anabolic-androgenic steroids.
abstract: The history of anabolic-androgenic steroids (AASs) is an interesting tale that has its roots in ancient "endocrinology." More than 6000 years ago, farmers noted enhanced domestication of animals after castration. The development of AASs, and, later, their artificial synthesis, have remained a hot topic in scientific research and pharmaceuticals. Over the years, AASs have been used as a proposed treatment for a wide variety of ailments, despite deleterious side effects. Unfortunately, they have been, and still are, abused by body builders, athletes, and teens.
authors.affiliation: Department of Pediatrics, Columbus Children's Hospital, 700 Children's Drive, Columbus, OH 43205, USA. dotsonj@chi.osu.edu
authors.forename: Jennifer L
authors.initials: JL
authors.lastname: Dotson
authors.forename: Robert T
authors.initials: RT
authors.lastname: Brown
mesh_terms: D045930:Anabolic Agents / Q000266:history*; D000728:Androgens / Q000266:history*; D000818:Animals; D004300:Doping in Sports / Q000266:history*; D049671:History, 18th Century; D049672:History, 19th Century; D049673:History, 20th Century; D049690:History, Ancient; D006801:Humans; D008297:Male; D045165:Testosterone Congeners / Q000266:history*
chemical_list: D045930:Anabolic Agents; D000728:Androgens; D045165:Testosterone Congeners