The use of ultrasound biomicroscopy in the evaluation of anterior segment tumors and simulating conditions.
OBJECTIVE
To report the ultrasound biomicroscopy (UBM) findings of anterior segment tumors and simulating conditions.


METHODS
Thirty-five patients underwent UBM. Of those, 16 had histopathologically or cytopathologically diagnosed tumors, and 19 had clinically diagnosed lesions.


RESULTS
The study material comprised 13 iris pigment epithelial (IPE) cysts, 7 ciliary body melanomas, 4 iris melanomas, 4 iris nevi, 3 intraocular invasions of conjunctival squamous cell carcinoma, 2 ring melanomas of the anterior chamber angle, 1 medulloepithelioma and 1 pars plana cyst. On UBM, all IPE cysts presented as cystic lesions with a thin cyst wall and no solid components. All ciliary body melanomas showed low to medium reflectivity, with cavitation in one case and extraocular extension in another. Iris melanomas presented as anterior (stromal) iris lesions with medium to high internal reflectivity. There was irregularity and convex bowing of the posterior iris plane in iris melanomas, a feature not seen in iris nevi. Intraocular invasion of conjunctival squamous cell carcinoma was evidenced as areas of medium to high reflectivity in the ciliary body and iris, loss of the acute angle shape and highly reflective spots in the anterior chamber.


CONCLUSIONS
UBM was particularly useful in the diagnosis of IPE cysts, in the visualization of small ciliary body melanomas, in the differentiation of iris melanomas from iris nevi and in the demonstration of intraocular invasion from conjunctival squamous cell carcinoma.
Gündüz
Kaan
K
Department of Ophthalmology, Ankara University Faculty of Medicine, Ankara, Turkey. eyemd@ada.net.tr
Hoşal
Banu M
BM
Zilelioğlu
Güler
G
Günalp
Ilhan
I
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000869:Anterior Eye Segment / Q000000981:diagnostic imaging*; D002294:Carcinoma, Squamous Cell / Q000000981:diagnostic imaging; D002924:Ciliary Body; D003230:Conjunctival Neoplasms / Q000000981:diagnostic imaging; D003560:Cysts / Q000000981:diagnostic imaging; D003937:Diagnosis, Differential; D005134:Eye Neoplasms / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D007499:Iris Diseases / Q000000981:diagnostic imaging; D015811:Iris Neoplasms / Q000000981:diagnostic imaging; D008297:Male; D008545:Melanoma / Q000000981:diagnostic imaging; D033401:Microscopy, Acoustic; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D009506:Nevus / Q000000981:diagnostic imaging