Solitary extramedullary plasmacytoma of the liver without systemic monoclonal gammopathy.
Extramedullary plasmacytoma of the liver is a very rare tumor. Although a few cases of extramedullary plasmacytoma of the liver have been reported, we could not find any report on truly localized extramedullary plasmacytoma of the liver in the literature. The patient was a 63-yr-old man who exhibited a solitary liver mass on dynamic computed tomography and magnetic resonance imaging. Histologically, the tumor was composed of mature plasma cells with mild atypia. Immunohistochemistry demonstrated monoclonal IgG and Kappa light chain expression. Bone marrow examination revealed no abnormalities. There was no evidence of a monoclonal protein in the serum and urine, lytic bone lesions, anemia, renal insufficiency, and hypercalcemia. The patient was treated with 5,000 cGy of radiotherapy, and the tumor disappeared 6 months after treatment.
Lee
Jun Young
JY
Department of Internal Medicine, Soonchunhyang University College of Medicine, Seoul, Korea.
Won
Jong Ho
JH
Kim
Hyun Jung
HJ
Bae
Sang Byung
SB
Kim
Chan Kyu
CK
Kim
Jung Hoon
JH
Lee
Nam Su
NS
Lee
Kyu Taeg
KT
Park
Sung Kyu
SK
Jin
So Young
SY
Hong
Dae Sik
DS
Park
Hee Sook
HS
D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis; D007145:Immunoglobulin kappa-Chains / Q000032:analysis; D007150:Immunohistochemistry; D008113:Liver Neoplasms / Q000276:immunology / Q000473:pathology* / Q000532:radiotherapy; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D008998:Monoclonal Gammopathy of Undetermined Significance / Q000276:immunology / Q000473:pathology; D010954:Plasmacytoma / Q000276:immunology / Q000473:pathology* / Q000532:radiotherapy; D014057:Tomography, X-Ray Computed
D007074:Immunoglobulin G; D007145:Immunoglobulin kappa-Chains