title: Constrictive pericarditis as an emerging manifestation of hyper-IgG4 disease.
abstract: A 68-year-old Japanese man was admitted for evaluation of right pleural effusion and bilateral leg edema that had progressively worsened over 6 months. As chest computed tomography revealed marked pericardial thickening, we performed a pericardiectomy, resulting in the remarkable improvement of his clinical manifestations. However, pleural fibrosis associated with fever of unknown origin soon developed. An elevated serum level of serum IgG4 and infiltration of IgG4-positive plasma cell in the resected pericardium were identified; thus, our patient might have hyper-IgG4 disease. Our case is the first report describing constrictive pericarditis as an initial manifestation of hyper-IgG4 disease.
authors.forename: Toshiro
authors.initials: T
authors.lastname: Sugimoto
authors.forename: Yoshikata
authors.initials: Y
authors.lastname: Morita
authors.forename: Keiji
authors.initials: K
authors.lastname: Isshiki
authors.forename: Takashi
authors.initials: T
authors.lastname: Yamamoto
authors.forename: Takashi
authors.initials: T
authors.lastname: Uzu
authors.forename: Atsunori
authors.initials: A
authors.lastname: Kashiwagi
authors.forename: Minoru
authors.initials: M
authors.lastname: Horie
authors.forename: Tohru
authors.initials: T
authors.lastname: Asai
mesh_terms: D000368:Aged; D005335:Fever of Unknown Origin / Q000209:etiology / Q000276:immunology; D006801:Humans; D006942:Hypergammaglobulinemia / Q000150:complications* / Q000276:immunology; D007074:Immunoglobulin G; D008297:Male; D010494:Pericarditis, Constrictive / Q000000981:diagnostic imaging* / Q000209:etiology* / Q000276:immunology; D010996:Pleural Effusion / Q000000981:diagnostic imaging / Q000209:etiology / Q000276:immunology; D014057:Tomography, X-Ray Computed
chemical_list: D007074:Immunoglobulin G