Organocatalytic enantioselective Friedel-Crafts reaction of pyrrole derivatives with imines.
A highly enantioselective Friedel-Crafts reaction of pyrrole derivatives with N-acyl imines catalyzed by chiral phosphoric acids was developed. The reactions produced the pyrrole derivatives in high yields and enantioselectivity.
Li
Guilong
G
Department of Chemistry, University of South Florida, 4202 East Fowler Avenue CHE205A, Tampa, Florida 33620, USA.
Rowland
Gerald B
GB
Rowland
Emily B
EB
Antilla
Jon C
JC