title: Evaluation of postsurgical recurrence in Crohn's disease: a new indication for capsule endoscopy?
abstract: BACKGROUND
  Recurrence after surgery to treat Crohn's disease is frequent and unpredictable. The efficacy of postsurgery capsule endoscopy in detecting recurrence in patients with Crohn's disease is yet to be confirmed.
  
  
  OBJECTIVE
  To assess the safety, accuracy, and therapeutic impact of capsule endoscopy in these patients.
  
  
  METHODS
  Crohn's disease recurrence at the neoileum (Rutgeers score) was assessed in the patients by colonoscopy and capsule endoscopy. The M2A Patency Capsule (Given Imaging, Yoqneam, Israel) was administered 1 week before capsule endoscopy. Capsule endoscopy was performed within 2 weeks of colonoscopy. Investigators were blinded to the results of each technique. Patient comfort during the procedures was recorded.
  
  
  METHODS
  Twenty-four patients with Crohn's disease with ileocolonic anastomosis were prospectively included. All patients were asymptomatic and did not receive any prophylactic treatment.
  
  
  METHODS
  Neoileum recurrence.
  
  
  RESULTS
  A colonoscopy was performed in all patients, although the neoileum could not be reached in 3 of them. M2A Patency Capsule excretion was delayed in 2 patients; thus capsule endoscopy was given only to 22 patients. Recurrence was visualized with colonoscopy in 6 patients and with capsule endoscopy in 5. Ten additional recurrences were visualized only with capsule endoscopy. Moreover, proximal involvement was detected in 13 patients. Therapeutic management was modified in 16 patients. All patients preferred capsule endoscopy.
  
  
  CONCLUSIONS
  Capsule endoscopy is more effective in the evaluation of recurrence after surgery for Crohn's disease and is better tolerated than colonoscopy. This is of significant therapeutic relevance.
authors.affiliation: Gastroenterology Unit, La Fe University Hospital, Valencia, Spain.
authors.forename: Vicente
authors.initials: V
authors.lastname: Pons Beltrán
authors.forename: Pilar
authors.initials: P
authors.lastname: Nos
authors.forename: Guillermo
authors.initials: G
authors.lastname: Bastida
authors.forename: Belén
authors.initials: B
authors.lastname: Beltrán
authors.forename: Lidia
authors.initials: L
authors.lastname: Argüello
authors.forename: Mariam
authors.initials: M
authors.lastname: Aguas
authors.forename: Angel
authors.initials: A
authors.lastname: Rubín
authors.forename: Virginia
authors.initials: V
authors.lastname: Pertejo
authors.forename: Teresa
authors.initials: T
authors.lastname: Sala
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000714:Anastomosis, Surgical; D053704:Capsule Endoscopy; D003106:Colon / Q000601:surgery; D003113:Colonoscopy; D003424:Crohn Disease / Q000175:diagnosis / Q000601:surgery*; D005260:Female; D006801:Humans; D007082:Ileum / Q000601:surgery; D008297:Male; D008875:Middle Aged; D010342:Patient Acceptance of Health Care; D011183:Postoperative Complications / Q000175:diagnosis*; D011446:Prospective Studies; D012008:Recurrence; D012680:Sensitivity and Specificity