Rheology of a polymer-based hybrid suspension composed of concentrated poly[(D,L-lactide)-co-glycolide] solution and inorganic salt particles.
Suspensions composed of a solution of a biodegradable polyester in a volatile organic solvent, and solid inorganic particles of size in the order of hundreds of microns have been very important in the fabrication of porous scaffolds in the field of tissue engineering. This article reports the basic rheological investigations of this complex fluid type. A Couette geometry covered by silicon oil was found to be an appropriate geometry to retain stability of the rheological measurements. Suspension viscosity increased with the particle volume fraction, and the extent of the increase was much larger than that predicted by the Einstein suspension equation. Both start-up dynamics at the inception of steady shear and relaxation after an abrupt change of oscillatory shear frequency in the suspension showed significantly different behaviors from those in the associated polymer solution. Particle reorganization upon change of rheological state was anticipated.
Jing
Dianying
D
Key Laboratory of Molecular Engineering of Polymers of Ministry of Education, Department of Macromolecular Science, Advanced Materials Laboratory, Fudan University, Shanghai 200433, China.
Ding
Jiandong
J
D019344:Lactic Acid / Q000737:chemistry*; D011100:Polyglycolic Acid / Q000737:chemistry*; D000077182:Polylactic Acid-Polyglycolic Acid Copolymer; D011108:Polymers / Q000737:chemistry*; D012212:Rheology / Q000379:methods*; D012827:Silicone Oils / Q000737:chemistry; D012965:Sodium Chloride / Q000737:chemistry*; D012996:Solutions; D013499:Surface Properties; D013997:Time Factors; D014783:Viscosity
D011108:Polymers; D012827:Silicone Oils; D012996:Solutions; D000077182:Polylactic Acid-Polyglycolic Acid Copolymer; D011100:Polyglycolic Acid; D019344:Lactic Acid; D012965:Sodium Chloride