title: [Chondroblastoma].
abstract: Chondroblastom, benign cartilage tissue neoplasm, accounts for 1% of all bone tumors. It is encountered in any skeletal bones mainly in persons aged 10 and 25 years. Morphologically, it is represented as large homogenous cells--well-defined oval polygonal chondroblasts with a fine eosinophilic cytoplasm, and a round-to-oval nucleus. Cartilaginous portions of chondroblastoma form lobular structures. The tumor always comprises single-to-multiple multinucleate giant cells. The pathognomonic sign of chondroblastoma is intercellular reticular basophilically stained calcifications as a mesh. Mitotic cells, rather than abnormal ones, are present. There are cases of primary malignant chondroblastomas.
authors.forename: I V
authors.initials: IV
authors.lastname: Bulycheva
authors.forename: L A
authors.initials: LA
authors.lastname: Semenov
authors.forename: A N
authors.initials: AN
authors.lastname: Makhson
authors.forename: A G
authors.initials: AG
authors.lastname: Zhukov
mesh_terms: D000328:Adult; D001859:Bone Neoplasms / Q000000981:diagnostic imaging* / Q000235:genetics / Q000628:therapy*; D002648:Child; D002804:Chondroblastoma / Q000000981:diagnostic imaging* / Q000235:genetics / Q000628:therapy*; D006801:Humans; D011379:Prognosis; D011859:Radiography