[Effect of viruses on the host cytokine system].
The review considers recent data on the mechanism of action of viruses on the host cytokine system. The inhibitory and stimulant effects of viruses and their antigens on the production of cytokines, interferons in particular, are described. Examples of the behavior of specific viruses are given. Particular emphasis is laid on the viruses of the Herpesvididae family. The role of cytokine gene polymorphism in the pathogenesis is discussed.
Zheleznikova
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D000818:Animals; D000956:Antigens, Viral / Q000276:immunology / Q000494:pharmacology; D016207:Cytokines / Q000037:antagonists & inhibitors / Q000096:biosynthesis* / Q000235:genetics; D006564:Herpesviridae / Q000276:immunology; D006801:Humans; D007111:Immunity, Cellular; D007372:Interferons / Q000037:antagonists & inhibitors / Q000096:biosynthesis; D011110:Polymorphism, Genetic; D000079424:Tumor Necrosis Factor Inhibitors; D048069:Tumor Necrosis Factors / Q000096:biosynthesis; D014777:Virus Diseases / Q000276:immunology*; D014780:Viruses / Q000276:immunology*
D000956:Antigens, Viral; D016207:Cytokines; D000079424:Tumor Necrosis Factor Inhibitors; D048069:Tumor Necrosis Factors; D007372:Interferons