Granular cell tumors of the abdominal wall.
Granular cell tumors (GCT) are found in virtually any body site, including the tongue, skin, subcutaneous tissue, breast, rectum and vulva. However, they are rarely seen in the abdominal wall. We report here on a rare case of GCT in the rectus muscle of the abdominal wall. A 44-year-old woman presented with a non-tender, hard mass in the right lower abdominal wall. Upon microscopic examination, the tumor was found to comprise of large polygonal cells with an abundant eosinophilic granular cytoplasm and round to oval nuclei. Upon immunohistochemical staining, the large cells showed S-100 and CD68 positive granular aggregates in the cytoplasm. Many lysosomes of variable size were observed in the cytoplasm.
An
Jung-Suk
JS
Department of Pathology, Ansan Hospital, College of Medicine, Korea University, 516 Gojan-dong, Danwon-gu, Ansan-si, Gyeonggi-do 425-707, Korea.
Han
Sun-Hee
SH
Hwang
Sung-Bae
SB
Lee
Ju-Han
JH
Min
Byung-Wook
BW
Um
Jun-Won
JW
Lee
Eung-Seok
ES
Park
Heum-Rye
HR
Kim
Young-Sik
YS
D000008:Abdominal Neoplasms / Q000378:metabolism / Q000473:pathology*; D000328:Adult; D005260:Female; D016586:Granular Cell Tumor / Q000378:metabolism / Q000473:pathology*; D006801:Humans; D007150:Immunohistochemistry; D017568:Rectus Abdominis / Q000378:metabolism / Q000473:pathology*; D009418:S100 Proteins / Q000378:metabolism
D009418:S100 Proteins