title: [Structure of the metaepiphyseal growth plate cartilage in conditions of total isolation from cellular and humoral influences after its transplantation into soft tissues (an experimental study)].
abstract: The aim of this study was to determine the effect of a skeletal muscle on the cartilage of growth plate of metaepiphyseal explants of tubular bones of growing and mature Chinchilla rabbits (n = 18) under conditions of their isolation from cellular and humoral influences. In experimental animals, metaepiphyseal explants of metatarsal bones, containing growth plate, were sealed in polyethylene film and were placed, under local anesthesia, in the femoral muscles. One week later these grafts were removed and studied histologically. Despite the absence of the effects of biologically active substances and immunocompetent cells of the donor (foreign) organism, the exposure of the cartilage plate to the environment of the muscular tissue lead to some typical changes in its structure. The results obtained may indicate the susceptibility of the cartilage growth plates to the action of some distant factors, probably, of an electromagnetic nature. The detection of these factors is promising for the development of clinical methods of the stimulation of the damaged cartilage growth plates for the correction of bone deformities.
authors.forename: I E
authors.initials: IE
authors.lastname: Nikitiuk
authors.forename: I V
authors.initials: IV
authors.lastname: Popov
authors.forename: V A
authors.initials: VA
authors.lastname: Polianskiĭ
authors.forename: V I
authors.initials: VI
authors.lastname: Dudkin
mesh_terms: D000818:Animals; D000917:Antibody Formation; D001846:Bone Development / Q000502:physiology*; D006132:Growth Plate / Q000254:growth & development / Q000502:physiology / Q000637:transplantation; D007111:Immunity, Cellular; D008682:Metatarsal Bones / Q000254:growth & development / Q000502:physiology / Q000637:transplantation; D018482:Muscle, Skeletal / Q000276:immunology / Q000502:physiology; D020959:Polyethylene; D011817:Rabbits
chemical_list: D020959:Polyethylene