Biogenic amine actions on cholangiocyte function.
Biogenic amines, such as serotonin, histamine, dopamine, and the catecholamines epinephrine and norepinephrine, regulate a multitude of cellular responses. A great deal of effort has been invested into understanding the effects of these molecules and their corresponding receptor systems on cholangiocyte secretion, apoptosis, and growth. This review summarizes the results of these efforts and highlights the importance of these regulatory molecules on the physiology and pathophysiology of cholangiocytes.
Demorrow
Sharon
S
The Division of Research and Education, Medical Research Building, Scott and White Hospital, 702 S.W. H.K. Dodgen Loop, Temple, TX 76504,USA. demorrow@medicine.tamhsc.edu
Francis
Heather
H
Alpini
Gianfranco
G
D000818:Animals; D017209:Apoptosis; D017734:Bile Ducts, Extrahepatic / Q000254:growth & development / Q000378:metabolism* / Q000473:pathology / Q000503:physiopathology; D001653:Bile Ducts, Intrahepatic / Q000254:growth & development / Q000378:metabolism* / Q000473:pathology / Q000503:physiopathology; D015306:Biogenic Monoamines / Q000378:metabolism*; D004847:Epithelial Cells / Q000378:metabolism* / Q000473:pathology; D006801:Humans; D017982:Receptors, Biogenic Amine / Q000378:metabolism*
D015306:Biogenic Monoamines; D017982:Receptors, Biogenic Amine