Nitazoxanide: a review of its use in the treatment of gastrointestinal infections.
Nitazoxanide (Alinia, Daxon, Dexidex, Paramix, Kidonax, Colufase, Annita) has in vitro activity against a variety of microorganisms, including a broad range of protozoa and helminths. Nitazoxanide is effective in the treatment of protozoal and helminthic infections, including Cryptosporidium parvum or Giardia lamblia, in immunocompetent adults and children, and is generally well tolerated. Nitazoxanide is a first-line choice for the treatment of illness caused by C. parvum or G. lamblia infection in immunocompetent adults and children, and is an option to be considered in the treatment of illnesses caused by other protozoa and/or helminths.
Anderson
Vanessa R
VR
Wolters Kluwer Health | Adis, Auckland, New Zealand. demail@adis.co.nz
Curran
Monique P
MP
D000890:Anti-Infective Agents / Q000009:adverse effects / Q000493:pharmacokinetics / Q000627:therapeutic use; D000977:Antiparasitic Agents / Q000009:adverse effects / Q000493:pharmacokinetics / Q000627:therapeutic use; D001424:Bacterial Infections / Q000188:drug therapy*; D005767:Gastrointestinal Diseases / Q000382:microbiology* / Q000469:parasitology*; D006801:Humans; D007411:Intestinal Diseases, Parasitic / Q000188:drug therapy; D009574:Nitro Compounds; D013844:Thiazoles / Q000009:adverse effects / Q000493:pharmacokinetics / Q000627:therapeutic use; D014777:Virus Diseases / Q000188:drug therapy*
D000890:Anti-Infective Agents; D000977:Antiparasitic Agents; D009574:Nitro Compounds; D013844:Thiazoles; C041747:nitazoxanide