[Shengli capsules enhance sexual ability in male rats].
OBJECTIVE
To evaluate the effects of Shengli capsules on the sexual ability of normal and castrated male rats.


METHODS
Shengli capsules were given by intragastric administration to 100 experimental male rats at different doses of 0.35, 0.70 and 1.40 g / kg. Data were collected and analyzed, including capture latency period, times of capture, sexual endurance and times of ejaculation, to assess the effects of Shengli capsules on the sexual ability of the rats. The Castrated Animal Impotence Model was employed to determine the erectile latency period and the function parameters of the preputial gland, seminal vesicle and prostate, so as to test the effects of Shengli on the development of the rats'sexual organs.


RESULTS
Shengli was proved to be effective in shortening copulation latency in the dose groups of 0.35, 0.70 and 1.40 g / kg (P < 0.01), increasing significantly the frequency of capture in the high- and low-dose groups of 0.35 and 1.40 g / kg (P < 0.05), reducing the latency period to erection in the low-dose group of 0.35 g / kg, and blocking the shrink of the seminal vesicle and prostate in the medium-dose group of 0.70 g / kg.


CONCLUSIONS
Shengli is significantly effective in enhancing the sexual ability of male rats: it can boost libido, increase erection frequency and improve sexual performance. However, further studies have yet to be done on its action mechanisms.
Fan
Yuan
Y
Yunnan Longrun Pharmaceutical Co., Ltd., Kunming, Yunnan 650101, China.
Liu
Zhu-Huan
ZH
Chen
Shao-Hong
SH
Cai
Ding-Bao
DB
Sun
Pang
P
Shang
Jian-Hua
JH
Wang
Xia
X
D000818:Animals; D002214:Capsules; D003307:Copulation / Q000187:drug effects; D004305:Dose-Response Relationship, Drug; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D005260:Female; D008297:Male; D009919:Orchiectomy; D010052:Ovariectomy; D010410:Penile Erection / Q000187:drug effects*; D051381:Rats; D017207:Rats, Sprague-Dawley; D012726:Sexual Behavior, Animal / Q000187:drug effects*
D002214:Capsules; D004365:Drugs, Chinese Herbal; C532630:shengli