title: Very late stent fracture associated with a sirolimus-eluting stent.
abstract: Late stent thrombosis (>1 year after implantation) is a recognised complication involving drug-eluting stents. Stent fracture is increasingly being reported as a complication of drug-eluting stent, and in particular sirolimus-eluting stent use. We report the case of very late sirolimus-eluting stent fracture resulting in an acute coronary syndrome. This case report highlights the need for greater awareness and post-marketing surveillance to detect a potential mechanism for late stent thrombosis in the drug-eluting stent era.
authors.affiliation: Cardiovascular Investigation Unit, Royal Adelaide Hospital, North Terrace, Adelaide, SA 5000, Australia. dleong@mail.rah.sa.gov.au
authors.forename: D P
authors.initials: DP
authors.lastname: Leong
authors.forename: B K
authors.initials: BK
authors.lastname: Dundon
authors.forename: R
authors.initials: R
authors.lastname: Puri
authors.forename: R A S
authors.initials: RA
authors.lastname: Yeend
mesh_terms: D054058:Acute Coronary Syndrome / Q000000981:diagnostic imaging / Q000209:etiology*; D000368:Aged; D017023:Coronary Angiography / Q000379:methods; D054855:Drug-Eluting Stents / Q000009:adverse effects*; D006801:Humans; D007166:Immunosuppressive Agents / Q000494:pharmacology*; D008297:Male; D011475:Prosthesis Failure; D020123:Sirolimus / Q000494:pharmacology*
chemical_list: D007166:Immunosuppressive Agents; D020123:Sirolimus