title: The efficacy and safety of cefovecin in the treatment of feline abscesses and infected wounds.
abstract: OBJECTIVE
  To determine the efficacy and safety of cefovecin for the treatment of bacterial abscesses and wounds in cats at clinics in Germany, France, Spain and the UK.
  
  
  METHODS
  Cats with abscesses or wounds were enrolled. Cats (217) were randomised to treatment with either cefovecin administered by subcutaneous injection at 14 day intervals or amoxicillin/clavulanic acid as twice-daily oral tablets for 14 days. Treatment courses were repeated at 14 day intervals, when deemed necessary. Clinicians assessing lesions were masked to treatment allocation. Only animals with a confirmed pretreatment bacterial pathogen were included in the efficacy analysis. Cases were evaluated 28 days after initiation of the final course of treatment.
  
  
  RESULTS
  Cefovecin was as efficacious as amoxicillin/clavulanic acid, and efficacy was 100 per cent for both treatments.
  
  
  CONCLUSIONS
  Cefovecin, administered as a single subcutaneous injection repeated at 14 day intervals as required, was shown to be as efficacious as oral amoxicillin/clavulanic acid in the treatment of abscesses/wounds in cats.
authors.affiliation: Veterinary Medicine Research & Development, Pfizer Ltd, Sandwich, Kent CT13 9NJ, UK.
authors.forename: M R
authors.initials: MR
authors.lastname: Stegemann
authors.forename: J
authors.initials: J
authors.lastname: Sherington
authors.forename: C
authors.initials: C
authors.lastname: Passmore
mesh_terms: D000038:Abscess / Q000188:drug therapy / Q000662:veterinary; D000284:Administration, Oral; D000658:Amoxicillin / Q000008:administration & dosage / Q000627:therapeutic use; D000818:Animals; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D002371:Cat Diseases / Q000188:drug therapy* / Q000473:pathology; D002415:Cats; D002511:Cephalosporins / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D019818:Clavulanic Acid / Q000008:administration & dosage / Q000627:therapeutic use; D005060:Europe; D005260:Female; D007279:Injections, Subcutaneous / Q000662:veterinary; D008297:Male; D016896:Treatment Outcome; D014946:Wound Infection / Q000188:drug therapy / Q000662:veterinary*
chemical_list: D000900:Anti-Bacterial Agents; D002511:Cephalosporins; C516253:cefovecin; D019818:Clavulanic Acid; D000658:Amoxicillin