The breast dynamic contrast enhanced MRI: preliminary results of a quantitative analysis.
The objective of our study was to apply a quantitative analysis to the dynamic contrast enhanced MR imaging of the breast. Automated criteria increase the objectivity and reproducibility of the diagnostic interpretation of the imaging for differentiating benign and malignant lesions. The validation of this applied method was evaluated by analysing the time- signal intensity curves and the performance of the extracted enhancement parameters. The performance of some extracted parameters was evaluated by ROC (Receiver Operating Characteristic) analysis. These parameters were found to be particularly accurate in differentiating lesions.
Di Nallo
A M
AM
Medical Physics and Expert System Laboratory, "Regina Elena" National Cancer Institute, Rome, Italy. dinallo@ifo.it
Crecco
M
M
Ortenzia
O
O
Ordonez
R
R
Abate
A
A
Benassi
M
M
D001940:Breast / Q000473:pathology; D001943:Breast Neoplasms / Q000175:diagnosis* / Q000473:pathology; D003287:Contrast Media / Q000008:administration & dosage*; D005260:Female; D019786:Gadolinium DTPA / Q000008:administration & dosage; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D012984:Software
D003287:Contrast Media; D019786:Gadolinium DTPA