title: Carbon nanotubes and glucose oxidase bionanocomposite bridged by ionic liquid-like unit: preparation and electrochemical properties.
abstract: For their biocompatibility and potential bionanoelectronic applications, integration of carbon nanotubes (CNTs) with biomolecules such as redox enzyme is highly anticipated. Therein, CNTs are expected to act not only as an electron transfer promoter, but also as immobilizing substrate for biomolecules. In this report, a novel method for immobilization of biomolecules on CNTs was proposed based on ionic interaction, which is of universality and widespread use in biological system. As illustrated, glucose oxidase (GOD) and single-walled carbon nanotubes (SWNTs) were integrated into a unitary bionanocomposite by means of ionic liquid-like unit on functionalized SWNTs. The resulted bionanocomposite illustrated better redox response of immobilized GOD in comparison of that prepared by weak physical absorption without ionic interaction. As a potential application of concept, the electrochemical detection of glucose was exemplified based on this novel bionanocomposite.
authors.affiliation: State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, and Graduate University of the Chinese Academy of Sciences, Chinese Academy of Sciences, Changchun 130022, PR China.
authors.forename: Yuanjian
authors.initials: Y
authors.lastname: Zhang
authors.forename: Yanfei
authors.initials: Y
authors.lastname: Shen
authors.forename: Dongxue
authors.initials: D
authors.lastname: Han
authors.forename: Zhijuan
authors.initials: Z
authors.lastname: Wang
authors.forename: Jixia
authors.initials: J
authors.lastname: Song
authors.forename: Fei
authors.initials: F
authors.lastname: Li
authors.forename: Li
authors.initials: L
authors.lastname: Niu
mesh_terms: D015374:Biosensing Techniques / Q000379:methods*; D004563:Electrochemistry / Q000379:methods*; D005947:Glucose / Q000032:analysis*; D005949:Glucose Oxidase / Q000737:chemistry*; D053761:Nanocomposites / Q000737:chemistry*; D037742:Nanotubes, Carbon / Q000737:chemistry*
chemical_list: D037742:Nanotubes, Carbon; D005949:Glucose Oxidase; D005947:Glucose