[The morphofunctional state of the blood-brain barrier at the level of the medulla oblongata in experimental West Nile encephalitis].
Pronounced clinical and morphological changes were found in the neurons and microcirculatory bed (MCB) vessels at the level of the medulla oblongata in experimental West Nile encephalitis (WNE). At the same time, the magnitude of changes in MCB vessels and nerve cells in the cores of the medulla oblongata correlated with the state of the surrounding astrocytic glia. It is suggested that the intensive astroglial reaction revealed during this experimental WNE reproduction promotes the prevention of neuronal lesion.
Pisarev
V B
VB
Shmidt
M V
MV
Petrov
V A
VA
D000818:Animals; D001253:Astrocytes / Q000473:pathology; D001812:Blood-Brain Barrier / Q000503:physiopathology*; D002196:Capillaries / Q000473:pathology / Q000648:ultrastructure; D005904:Glial Fibrillary Acidic Protein / Q000378:metabolism; D008526:Medulla Oblongata / Q000098:blood supply / Q000378:metabolism / Q000503:physiopathology*; D051379:Mice; D008854:Microscopy, Electron; D009474:Neurons / Q000473:pathology / Q000648:ultrastructure; D014901:West Nile Fever / Q000503:physiopathology*
D005904:Glial Fibrillary Acidic Protein