Eosinophilic gastroenteritis with cytomegalovirus infection in an immunocompetent child.
A 3-year-old boy developed transient protein-losing gastroenteropathy associated with cytomegalovirus (CMV) infection. Both IgG and IgM antibodies to CMV were positive in a serologic blood test. Upper gastrointestinal endoscopy showed multiple erosions throughout the body of the stomach, without enlarged gastric folds. Histological examination of the biopsy specimens indicated eosinophilic gastroenteritis and CMV infection. The patient had complete resolution without specific therapy for CMV in four weeks. An allergic reaction as well as CMV infection played important roles in the pathogenesis of this case.
Takeyama
Junji
J
Department of Pathology, Miyagi Children's Hospital, 4-3-17 Ochiai, Sendai, Japan. jtakeyama@miyagi-children.or.jp
Abukawa
Daiki
D
Miura
Katsushi
K
D000914:Antibodies, Viral / Q000097:blood*; D002675:Child, Preschool; D003587:Cytomegalovirus / Q000276:immunology*; D003586:Cytomegalovirus Infections / Q000150:complications* / Q000276:immunology / Q000473:pathology; D004802:Eosinophilia / Q000150:complications* / Q000276:immunology / Q000473:pathology / Q000821:virology; D005512:Food Hypersensitivity / Q000150:complications* / Q000276:immunology / Q000473:pathology; D005759:Gastroenteritis / Q000150:complications* / Q000276:immunology / Q000473:pathology / Q000821:virology; D006801:Humans; D007121:Immunocompetence; D007074:Immunoglobulin G / Q000097:blood; D007075:Immunoglobulin M / Q000097:blood; D008297:Male; D011504:Protein-Losing Enteropathies / Q000276:immunology / Q000473:pathology / Q000821:virology*; D013270:Stomach / Q000276:immunology / Q000473:pathology / Q000821:virology
D000914:Antibodies, Viral; D007074:Immunoglobulin G; D007075:Immunoglobulin M