title: Is the brain biopsy obligatory or not for the diagnosis of Schilder's disease? Review of the literature.
abstract: BACKGROUND
  Schilder's myelinoclastic diffuse sclerosis (Schilder's disease) is a rare demyelinating disorder. Clinical features and neuroimaging findings of this disease might mimic an intra-cranial mass lesion including an abscess or a tumour.
  
  
  METHODS
  Clinical and radiological findings of two children with the diagnosis of Shilder's disease are reported, and the role of brain biopsy as a diagnostic tool is discussed.
authors.affiliation: Department of Pediatrics, Division of Pediatric Neurology, Marmara University, School of Medicine, Istanbul, Turkey. yukselymd@e-kolay.net
authors.forename: Yuksel
authors.initials: Y
authors.lastname: Yilmaz
authors.forename: Canan
authors.initials: C
authors.lastname: Kocaman
authors.forename: Hakan
authors.initials: H
authors.lastname: Karabagli
authors.forename: Memet
authors.initials: M
authors.lastname: Ozek
mesh_terms: D001706:Biopsy / Q000379:methods / Q000592:standards; D001921:Brain / Q000187:drug effects / Q000473:pathology*; D002648:Child; D002549:Diffuse Cerebral Sclerosis of Schilder / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D013256:Steroids / Q000008:administration & dosage / Q000627:therapeutic use
chemical_list: D013256:Steroids