title: [From cocaine to innovative antiemetics. The medicinal chemistry of 5-ht3 receptor antagonists].
authors.affiliation: Institut für Pharmazeutische Chemie, Zentrum für Arzneimittelforschung, Entwicklung und Sicherheit, Max-von-Laue-Str. 9, 60438 Frankfurt.
authors.forename: Heiko
authors.initials: H
authors.lastname: Zettl
authors.forename: Manfred
authors.initials: M
authors.lastname: Schubert-Zsilavecz
authors.forename: Carsten D
authors.initials: CD
authors.lastname: Siebert
mesh_terms: D000818:Animals; D000932:Antiemetics / Q000737:chemistry / Q000493:pharmacokinetics / Q000494:pharmacology / Q000627:therapeutic use*; D000970:Antineoplastic Agents / Q000009:adverse effects; D003042:Cocaine / Q000737:chemistry / Q000493:pharmacokinetics / Q000494:pharmacology / Q000627:therapeutic use*; D006801:Humans; D058831:Serotonin 5-HT3 Receptor Antagonists; D012702:Serotonin Antagonists / Q000737:chemistry / Q000493:pharmacokinetics / Q000494:pharmacology / Q000627:therapeutic use*; D013329:Structure-Activity Relationship; D014839:Vomiting / Q000139:chemically induced / Q000517:prevention & control*
chemical_list: D000932:Antiemetics; D000970:Antineoplastic Agents; D058831:Serotonin 5-HT3 Receptor Antagonists; D012702:Serotonin Antagonists; D003042:Cocaine