Micro- and nanofabrication methods in nanotechnological medical and pharmaceutical devices.
Micro- and nanofabrication techniques have revolutionized the pharmaceutical and medical fields as they offer the possibility for highly reproducible mass-fabrication of systems with complex geometries and functionalities, including novel drug delivery systems and bionsensors. The principal micro- and nanofabrication techniques are described, including photolithography, soft lithography, film deposition, etching, bonding, molecular self assembly, electrically induced nanopatterning, rapid prototyping, and electron, X-ray, colloidal monolayer, and focused ion beam lithography. Application of these techniques for the fabrication of drug delivery and biosensing systems including injectable, implantable, transdermal, and mucoadhesive devices is described.
Betancourt
Tania
T
Department of Biomedical, Engineering, The University of Texas at Austin, TX, USA.
Brannon-Peppas
Lisa
L
D001672:Biocompatible Materials / Q000737:chemistry*; D015374:Biosensing Techniques / Q000379:methods*; D016503:Drug Delivery Systems / Q000379:methods*; D004345:Drug Industry / Q000379:methods*; D004867:Equipment Design; D019544:Equipment Failure Analysis; D049329:Nanostructures / Q000737:chemistry* / Q000627:therapeutic use* / Q000648:ultrastructure; D036103:Nanotechnology / Q000379:methods*
D001672:Biocompatible Materials