[Optimizing the best extraction condition of semi-bionic extraction for licorice by unifrom design].
OBJECTIVE
To optimize the best extraction condition of semi-bionic extraction for licorice.


METHODS
The best extraction condition of the semi-bionic extraction for licorice by uniform design was optimized with glycyrrhizic acid, total flavonoids, total polysaccharides, total HPLC integrate area and dried extract weight as the indexes.


RESULTS
The optimized technologic condition: The pH values of the water for the 1st, 2nd, and 3rd decoctions were in order of 5.88, 7.50, and 8.90, and the total extraction time was 3.93 h.


CONCLUSIONS
According to industry production condition, the best SBE technologic condition is: The pH values of the water for the 3 decoctions are in order of 6.0, 7.5, and 9.0, and the extraction time are 2h, 1h, and 1h, respectively.
Cheng
Yan-Qin
YQ
401th Hospital of PLA, Qingdao 266071, China.
Sun
Xiu-Mei
XM
Zhang
Zhao-Wang
ZW
Hui
Jian-Guo
JG
D004365:Drugs, Chinese Herbal / Q000737:chemistry* / Q000302:isolation & purification; D005419:Flavonoids / Q000032:analysis*; D006035:Glycyrrhiza / Q000737:chemistry*; D019695:Glycyrrhizic Acid / Q000032:analysis*; D006358:Hot Temperature; D006863:Hydrogen-Ion Concentration; D018517:Plant Roots / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry; D011134:Polysaccharides / Q000032:analysis; D027343:Rhizome / Q000737:chemistry; D013678:Technology, Pharmaceutical / Q000379:methods*; D013997:Time Factors
D004365:Drugs, Chinese Herbal; D005419:Flavonoids; D011134:Polysaccharides; D019695:Glycyrrhizic Acid