title: Paraneoplastic pemphigus presenting as erythrodermic lichenoid dermatitis with concomitant features of pemphigus foliaceus.
abstract: We describe a patient with paraneoplastic pemphigus who presented with erythrodermic lichenoid dermatitis, later developing blisters of pemphigus foliaceus type and oral erosive lesions. In addition to antibodies against the plakin family proteins, the patient's serum was positive for anti-desmoglein 1 antibodies without coexisting anti-desmoglein 3 activities by enzyme-linked immunosorbent assay, which is a very rare autoantibody profile in paraneoplastic pemphigus.
authors.affiliation: Department of Dermatology, Nara Medical University School of Medicine, Nara, Japan. tfukumot@naramed-u.ac.jp
authors.forename: Takaya
authors.initials: T
authors.lastname: Fukumoto
authors.forename: Yoshimi
authors.initials: Y
authors.lastname: Shiroyama
authors.forename: Hironori
authors.initials: H
authors.lastname: Niizeki
authors.forename: Nobuhiko
authors.initials: N
authors.lastname: Kobayashi
authors.forename: Hideo
authors.initials: H
authors.lastname: Asada
authors.forename: Norito
authors.initials: N
authors.lastname: Ishii
authors.forename: Takashi
authors.initials: T
authors.lastname: Hashimoto
authors.forename: Sachiko
authors.initials: S
authors.lastname: Miyagawa
mesh_terms: D001323:Autoantibodies / Q000097:blood*; D003873:Dermatitis, Exfoliative / Q000209:etiology; D051183:Desmoglein 1 / Q000276:immunology; D051184:Desmoglein 3 / Q000276:immunology; D005260:Female; D005802:Genes, MHC Class II; D006801:Humans; D007159:Immunologic Tests; D017512:Lichenoid Eruptions / Q000209:etiology; D008875:Middle Aged; D009061:Mouth Mucosa / Q000473:pathology*; D010257:Paraneoplastic Syndromes / Q000150:complications / Q000175:diagnosis* / Q000276:immunology; D010392:Pemphigus / Q000150:complications / Q000175:diagnosis* / Q000276:immunology; D012867:Skin / Q000276:immunology / Q000473:pathology*
chemical_list: D001323:Autoantibodies; D051183:Desmoglein 1; D051184:Desmoglein 3