[Biochemical and functional characteristics of erythrocyte membranes in sportsmens with anemia].
In the article the changes of lipid-protein bilayer of erythrocyte membrane, their structural-functional particularities and activities of lipid peroxidation in interrelation with anemia's parameters in athletes. It was shown that under the intensive prolonged physical load activation of lipid peroxidation in erythrocyte membranes led to significant changes of functional parameters accompanied by increased aggregation and permeability, glycocalix sorption ability and sorption capacity along with simultaneous alteration of phospholipid and protein membrane bilayer. These membrane changes in 75% athletes accociated with anemia development which correlates with degree of biochemical and structural-functional changes in erythrocyte membrane that requires correction by antioxidant and membranoprotective therapy on stage of athletes preparation.
Hunina
L M
LM
Oliĭnyk
S A
SA
Ivanov
S V
SV
D000328:Adult; D000740:Anemia / Q000097:blood* / Q000378:metabolism; D002463:Cell Membrane Permeability; D004910:Erythrocyte Membrane / Q000378:metabolism*; D015444:Exercise; D006454:Hemoglobins / Q000032:analysis; D006801:Humans; D015227:Lipid Peroxidation; D008563:Membrane Lipids / Q000378:metabolism*; D008565:Membrane Proteins / Q000378:metabolism*; D013177:Sports
D006454:Hemoglobins; D008563:Membrane Lipids; D008565:Membrane Proteins