title: [Diagnostic difficulties in foodborne botulism--case reports and literature review].
abstract: Food borne botulism is a relatively rare clinical syndrome, which symptomatology is generally highly distinctive. The physicians of various specialties should be familiar with the symptoms of botulism because its sings concern the nervous system, the organ of sight and the gastrointestinal system. In older persons with coexisting chronic diseases some symptoms of botulism may be not distinctive or may mimic exacerbation of early existing diseases. The handbook descriptions present the food borne botulism as dramatic and often deadly disease. However in some cases this disease can have mild course and poor symptomatology. Two cases of food borne botulism with different clinical course are presented in this paper, when the correct diagnosis was established with delay. A 78-year-old man was admitted with the symptoms of pneumonia and dizziness of uncertain aetiology. The diagnosis of food borne botulism was established in 10th day of hospital stay, when the most symptoms were not present. Despite of such late diagnosis and relatively good patient's condition a therapy with antitoxin was administrated. The second case reports a 70-year-old man with chronic heart failure, diabetes and obesity, when the delay of correct diagnosis was about of 24 hours. Despite of relatively early antitoxin administration and intensive supportive care patient died in 11th day of hospital stay.
authors.affiliation: Oddział Chorób Wewnetrznych, Wojewódzkiego Szpitala Specjalistycznego w Białej Podlaskiej. pchwaluk@poczta.fm
authors.forename: Paweł
authors.initials: P
authors.lastname: Chwaluk
authors.forename: Agnieszka
authors.initials: A
authors.lastname: Chwaluk
mesh_terms: D000368:Aged; D001904:Botulinum Antitoxin / Q000627:therapeutic use*; D001905:Botulinum Toxins / Q000506:poisoning*; D001906:Botulism / Q000175:diagnosis* / Q000209:etiology / Q000628:therapy; D003014:Clostridium botulinum / Q000302:isolation & purification; D003422:Critical Care / Q000379:methods; D003937:Diagnosis, Differential; D004244:Dizziness / Q000382:microbiology; D004638:Emergency Treatment; D017809:Fatal Outcome; D005516:Food Microbiology; D006801:Humans; D008297:Male; D008461:Meat Products / Q000382:microbiology*; D011014:Pneumonia / Q000382:microbiology; D011044:Poland; D016896:Treatment Outcome
chemical_list: D001904:Botulinum Antitoxin; D001905:Botulinum Toxins