title: Mutations in cryopyrin: bypassing roadblocks in the caspase 1 inflammasome for interleukin-1beta secretion and disease activity.
authors.affiliation: University
authors.forename: Charles A
authors.initials: CA
authors.lastname: Dinarello
mesh_terms: D002352:Carrier Proteins / Q000235:genetics*; D020170:Caspase 1 / Q000502:physiology*; D006801:Humans; D007249:Inflammation / Q000235:genetics* / Q000276:immunology*; D053583:Interleukin-1beta / Q000378:metabolism*; D009097:Multienzyme Complexes; D009154:Mutation; D000071199:NLR Family, Pyrin Domain-Containing 3 Protein
chemical_list: D002352:Carrier Proteins; D053583:Interleukin-1beta; D009097:Multienzyme Complexes; D000071199:NLR Family, Pyrin Domain-Containing 3 Protein; C453881:NLRP3 protein, human; D020170:Caspase 1