title: Gynaecological sarcomas.
abstract: OBJECTIVE
  To review gynaecological sarcomas, their management and future perspectives.
  
  
  RESULTS
  Soft tissue sarcomas are a group of tumours consisting of a wide variety of subtypes. The most common subtypes encountered in the female tract are uterine leiomyosarcomas and endometrial stromal sarcomas. Other subtypes do occur but at a much lower frequency. Mixed Müllerian tumours were previously considered to be a subtype of sarcoma, but recent evidence has revealed that they should in fact be regarded as carcinomas. Given the different approaches for different subtypes of sarcomas, their rarity and the complexity of treatment, the management of patients with gynaecological sarcomas should be delivered by multidisciplinary teams experienced in the treatment of these entities.
  
  
  CONCLUSIONS
  Gynaecological sarcomas are rare tumours and are treated differently from gynaecological carcinomas. Hopefully, improved insight into the pathogenesis of gynaecological sarcomas will yield novel therapies in the near future.
authors.affiliation: Department of Medical Oncology, Erasmus University Medical Centre, Daniel den Hoed Cancer Centre, Rotterdam, The Netherlands. s.sleijfer@erasmusmc.nl
authors.forename: Stefan
authors.initials: S
authors.lastname: Sleijfer
authors.forename: Caroline
authors.initials: C
authors.lastname: Seynaeve
authors.forename: Jaap
authors.initials: J
authors.lastname: Verweij
mesh_terms: D005260:Female; D005833:Genital Neoplasms, Female / Q000145:classification / Q000175:diagnosis / Q000628:therapy; D006801:Humans; D012509:Sarcoma / Q000145:classification / Q000175:diagnosis / Q000628:therapy