title: A novel HLA-G allele, HLA-G*010111, in the Brazilian population.
abstract: The human leukocyte antigen-G (HLA-G) gene plays an important role in pregnancy and is related to negative signals for natural killer cells and T lymphocytes. Herein a new HLA-G allele (HLA-G*010111) is described in the Brazilian population--one of the most heterogeneous populations in the world. The new allele is associated with the 14-bp deletion at exon 8 and is similar to the HLA-G*01010105 allele, except for a C to G transversion at codon 117 in exon 3.
authors.affiliation: Division of Clinical Immunology, Department of Medicine, School of Medicine of Ribeirão Preto, University of São Paulo, Avenida Bandeirantes 3900, 14049-900 Ribeirão Preto, São Paulo, Brazil. castelli@usp.br
authors.forename: E C
authors.initials: EC
authors.lastname: Castelli
authors.forename: C T
authors.initials: CT
authors.lastname: Mendes-Junior
authors.forename: C E V
authors.initials: CE
authors.lastname: Wiezel
authors.forename: N T A
authors.initials: NT
authors.lastname: Peres
authors.forename: A L
authors.initials: AL
authors.lastname: Simões
authors.forename: N M M
authors.initials: NM
authors.lastname: Rossi
authors.forename: E A
authors.initials: EA
authors.lastname: Donadi
mesh_terms: D000483:Alleles; D001483:Base Sequence; D001938:Brazil; D006680:HLA Antigens / Q000235:genetics*; D059951:HLA-G Antigens; D015395:Histocompatibility Antigens Class I / Q000235:genetics*; D006801:Humans; D008969:Molecular Sequence Data; D020641:Polymorphism, Single Nucleotide; D011153:Population
chemical_list: D006680:HLA Antigens; D059951:HLA-G Antigens; D015395:Histocompatibility Antigens Class I