title: Fatal post-traumatic zygomycosis in an immunocompetent young patient.
abstract: Zygomycosis, a relatively uncommon infection, usually occurs among immunocompromised individuals. It has been reported only rarely in trauma patients. A fatal case is reported of pulmonary and rapidly progressive cutaneous zygomycosis in a young, otherwise healthy farmer, with multiple bone fractures, wounds and soft tissue injuries after an accident with an agricultural machine in the field. Rhizopus spp. was isolated from both cultures of bronchial washings and wound samples. The diagnosis was confirmed by histopathological examination of tissue specimens from a large wound. Despite systemic antifungal therapy and surgical debridement, the patient's condition deteriorated and he died from refractory septic shock.
authors.affiliation: Critical Care Department, Medical School of Athens University, Evangelismos Hospital, Athens, Greece.
authors.forename: Marina
authors.initials: M
authors.lastname: Kontogiorgi
authors.affiliation: Critical Care Department, Medical School of Athens University, Evangelismos Hospital, Athens, Greece.
authors.forename: Ioannis
authors.initials: I
authors.lastname: Floros
authors.affiliation: Critical Care Department, Medical School of Athens University, Evangelismos Hospital, Athens, Greece.
authors.forename: Apostolos
authors.initials: A
authors.lastname: Koroneos
authors.affiliation: Department of Pathology, Evangelismos Hospital, Athens, Greece.
authors.forename: Chrysanthi
authors.initials: C
authors.lastname: Vamvouka
authors.affiliation: Department of Clinical Microbiology, Evangelismos Hospital, Athens, Greece.
authors.forename: Olga
authors.initials: O
authors.lastname: Paniara
authors.affiliation: Critical Care Department, Medical School of Athens University, Evangelismos Hospital, Athens, Greece.
authors.forename: Charis
authors.initials: C
authors.lastname: Roussos
authors.affiliation: Critical Care Department, Medical School of Athens University, Evangelismos Hospital, Athens, Greece.
authors.forename: Christina
authors.initials: C
authors.lastname: Routsi
mesh_terms: D000328:Adult; D000935:Antifungal Agents / Q000627:therapeutic use; D001992:Bronchoalveolar Lavage Fluid / Q000382:microbiology; D017809:Fatal Outcome; D006801:Humans; D008297:Male; D012233:Rhizopus / Q000302:isolation & purification*; D012772:Shock, Septic; D014947:Wounds and Injuries / Q000150:complications* / Q000382:microbiology; D020096:Zygomycosis / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy / Q000601:surgery
chemical_list: D000935:Antifungal Agents