APRIL but not BLyS serum levels are increased in chronic lymphocytic leukemia: prognostic relevance of APRIL for survival.
APRIL (a proliferation-inducing ligand) and BLyS (B lymphocyte stimulator) expression have been reported in chronic lymphocytic leukemia (CLL) cells. We examined APRIL and BLyS serum levels in CLL patients and evaluated the prognostic significance of APRIL expression on survival.
Planelles
Lourdes
L
Castillo-Gutiérrez
Sonia
S
Medema
Jan Paul
JP
Morales-Luque
Antonio
A
Merle-Béral
Hélène
H
Hahne
Michael
M
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000097:blood* / Q000401:mortality; D008297:Male; D008875:Middle Aged; D016133:Polymerase Chain Reaction; D011379:Prognosis; D018124:Receptors, Tumor Necrosis Factor / Q000097:blood*; D012189:Retrospective Studies; D015996:Survival Rate; D053300:Tumor Necrosis Factor Ligand Superfamily Member 13 / Q000097:blood*
C120197:BLyS receptor; D018124:Receptors, Tumor Necrosis Factor; D053300:Tumor Necrosis Factor Ligand Superfamily Member 13