Pseudoexfoliation syndrome: in vivo confocal microscopy analysis.
Pseudoexfoliation (PEX) syndrome is a common ocular disease that also affects the cornea. A case of clinical PEX syndrome, studied by in vivo corneal confocal microscopy is reported. The morphological analysis of the confocal images demonstrated hyper-reflective deposits and several dendritic cells in the basal epithelial layer. A fibrillar subepithelial structure was also found. The endothelial layer showed cell anomalies (polymegathism and pleomorphism) and hyper-reflective small endothelial deposits. Confocal microscopy is an in vivo imaging method that may provide new information on corneal alterations in PEX, and detect early corneal features.
Martone
Gianluca
G
Casprini
Fabrizio
F
Traversi
Claudio
C
Lepri
Francesca
F
Pichierri
Patrizia
P
Caporossi
Aldo
A
D002452:Cell Count; D003316:Corneal Diseases / Q000473:pathology*; D003713:Dendritic Cells / Q000473:pathology; D004728:Endothelium, Corneal / Q000473:pathology; D017889:Exfoliation Syndrome / Q000473:pathology*; D006801:Humans; D008297:Male; D018613:Microscopy, Confocal; D008875:Middle Aged