Percutaneous devices for stroke prevention.
The most important approaches to prevent cerebral ischemia by catheter technique are patent foramen ovale (PFO) closure in patients with a history of cryptogenic stroke and left atrial appendage (LAA) occlusion in atrial fibrillation (AF) patients. Over the past years, several new devices have been developed for these procedures. Results of randomized trials comparing device therapy, antiplatelet, or anticoagulation therapy are still not available. However, several nonrandomized studies have shown promising results. This article gives a review on the current results and techniques of the most commonly used devices as well as on new developments and approaches to catheter-based stroke prevention.
Bayard
Yves L
YL
CardioVascular Center Frankfurt, Sankt Katharinen, Frankfurt, Germany.
Ostermayer
Stefan H
SH
Hein
Ralph
R
Skowasch
Marijke
M
Büscheck
Franziska
F
Baranowski
Andreas
A
Heinisch
Corinna
C
Sievert
Horst
H
D020517:Atrial Appendage / Q000601:surgery; D001281:Atrial Fibrillation / Q000150:complications / Q000601:surgery / Q000628:therapy*; D021721:Balloon Occlusion / Q000295:instrumentation*; D002545:Brain Ischemia / Q000150:complications / Q000209:etiology / Q000517:prevention & control*; D006328:Cardiac Catheterization / Q000295:instrumentation*; D006348:Cardiac Surgical Procedures; D004867:Equipment Design; D006344:Heart Septal Defects, Atrial / Q000150:complications / Q000628:therapy*; D006801:Humans; D008026:Ligation; D020521:Stroke / Q000209:etiology / Q000517:prevention & control*; D016896:Treatment Outcome