Cutaneous leishmaniasis: clinical report of two cases and review of the recent literature.
With 1-1.5 million cases reported every year cutaneous leishmaniasis represents an increasing health problem. The course of cutaneous leishmaniasis varies from a single self-healing ulcer to a persistent ulcer or progressive mucosal disease with nasopharyngeal destruction. An enormous array of topical and systemic treatment modalities has been endorsed. The response to treatment depends on the species of parasite as well as the host's immunological and genetic status. Species-specific treatment guidelines based on evidence from controlled studies are highly desirable. We present two cases of cutaneous leishmaniasis, one in a child and one during pregnancy, reviewing various diagnostic and therapeutic measures with special attention to problems in young and pregnant patients.
Valesky
Eva Maria
EM
Department of Dermatology and Venerology, Johann Wolfgang Goethe-University, Frankfurt, Germany. eva.valesky@kgu.de
Thaçi
Diamant
D
Meissner
Markus
M
Beier
Christian
C
Wolter
Manfred
M
Schöfer
Helmut
H
Kaufmann
Roland
R
D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D002675:Child, Preschool; D017679:Cryotherapy; D005260:Female; D006801:Humans; D016773:Leishmaniasis, Cutaneous / Q000175:diagnosis*; D011247:Pregnancy; D016896:Treatment Outcome
D000900:Anti-Bacterial Agents