title: The sensitivity of preoperative scanning in regional recurrence of papillary thyroid cancer.
abstract: BACKGROUND
  The treatment of patients with regionally recurrent papillary carcinoma of the thyroid is a matter of controversy. Radioactive nodal picking was proposed as an alternative to neck dissection in these patients.
  
  
  METHODS
  We analyzed neck dissection specimens in 20 patients with PTC and compared the results to preoperative total-body scan (TBS) following a therapeutic dose of I(131)and ultrasonographic findings.
  
  
  RESULTS
  Eighteen patients underwent paratracheal neck dissection and 10 patients had a lateral neck dissection. Preoperative TBS detected the correct number of positive nodes in only 1 patient (5%) and the correct number of patients with positive nodes in 6/20 (30%) of the patients. US detected 32/98 positive nodes (36%) and 20/20 (100%) of the patients. Prediction of the number of positive nodes for both TBS and US was low (5% and 10%, respectively).
  
  
  CONCLUSIONS
  Preoperative TBS and/or US cannot satisfactorily predict metastatic lymph node involvement and cannot safely delineate limited surgery to replace formal neck dissection in patients with regionally recurrent PTC.
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, Tel-Aviv Sourasky Medical Center, Tel-Aviv University, Tel-Aviv, Israel. avironit@bezeqint.net
authors.forename: Avi
authors.initials: A
authors.lastname: Khafif
authors.forename: Rami
authors.initials: R
authors.lastname: Ben-Yosef
authors.forename: Ada
authors.initials: A
authors.lastname: Kesler
authors.forename: Leonor
authors.initials: L
authors.lastname: Trejo-Laider
authors.forename: Roee
authors.initials: R
authors.lastname: Landsberg
authors.forename: Hanna
authors.initials: H
authors.lastname: Patchornik
authors.forename: Einat
authors.initials: E
authors.lastname: Even-Sapir
authors.forename: Dan M
authors.initials: DM
authors.lastname: Fliss
mesh_terms: D000328:Adult; D000368:Aged; D002291:Carcinoma, Papillary / Q000175:diagnosis* / Q000556:secondary* / Q000628:therapy; D005260:Female; D006801:Humans; D007457:Iodine Radioisotopes / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D037981:Neck Dissection; D011237:Predictive Value of Tests; D011300:Preoperative Care; D019275:Radiopharmaceuticals / Q000627:therapeutic use; D013964:Thyroid Neoplasms / Q000473:pathology* / Q000628:therapy; D051598:Whole Body Imaging
chemical_list: D007457:Iodine Radioisotopes; D019275:Radiopharmaceuticals