Alzheimer's disease, trisomy 21, and myeloproliferative disorders: associations suggesting a genetic diathesis.
Relatives of probands with Alzheimer's disease had excessive incidences of trisomy 21 and myeloproliferative disorders. Microtubules are structures that are likely to be affected by a genetic defect causing a predisposition to Alzheimer's disease, trisomy 21 and, possibly, to myeloproliferative disorders.
Heston
L L
LL