title: Pseudoexfoliation syndrome: in vivo confocal microscopy analysis.
abstract: Pseudoexfoliation (PEX) syndrome is a common ocular disease that also affects the cornea. A case of clinical PEX syndrome, studied by in vivo corneal confocal microscopy is reported. The morphological analysis of the confocal images demonstrated hyper-reflective deposits and several dendritic cells in the basal epithelial layer. A fibrillar subepithelial structure was also found. The endothelial layer showed cell anomalies (polymegathism and pleomorphism) and hyper-reflective small endothelial deposits. Confocal microscopy is an in vivo imaging method that may provide new information on corneal alterations in PEX, and detect early corneal features.
authors.forename: Gianluca
authors.initials: G
authors.lastname: Martone
authors.forename: Fabrizio
authors.initials: F
authors.lastname: Casprini
authors.forename: Claudio
authors.initials: C
authors.lastname: Traversi
authors.forename: Francesca
authors.initials: F
authors.lastname: Lepri
authors.forename: Patrizia
authors.initials: P
authors.lastname: Pichierri
authors.forename: Aldo
authors.initials: A
authors.lastname: Caporossi
mesh_terms: D002452:Cell Count; D003316:Corneal Diseases / Q000473:pathology*; D003713:Dendritic Cells / Q000473:pathology; D004728:Endothelium, Corneal / Q000473:pathology; D017889:Exfoliation Syndrome / Q000473:pathology*; D006801:Humans; D008297:Male; D018613:Microscopy, Confocal; D008875:Middle Aged