[Resected pulmonary sarcoidosis after corticosteroid treatment still showing pathological granulomatous inflammation].
It is not well understood what kind of histologic resolution is obtained with corticosteroid medication in sarcoidosis, or how we are able to judge cure in that disease. We examined the cases of sarcoidosis who were under steroid medication and received lobectomy and lymphadenectomy for combined lung cancer. Steroid treatment had been introduced for the relief of visual disturbance, not for the pulmonary lesion. Administration of corticosteroid improves clinical, laboratory, bronchoalveolar lavage and radiological findings, but it is difficult to make histological granulomatous inflammation completely disappear. Improvement of radiological and clinical problems in sarcoidosis is not the same as complete cure in patients with steroid-treated sarcoidosis.
Kobayashi
Hideo
H
Third Department of Internal Medicine, National Defense Medical College.
Kanoh
Soichiro
S
Motoyoshi
Kazuo
K
Ozeki
Yuichi
Y
D000305:Adrenal Cortex Hormones / Q000494:pharmacology* / Q000627:therapeutic use; D005260:Female; D006099:Granuloma / Q000473:pathology*; D006801:Humans; D007249:Inflammation; D008168:Lung / Q000000981:diagnostic imaging / Q000473:pathology*; D008175:Lung Neoplasms / Q000150:complications / Q000601:surgery; D008197:Lymph Node Excision; D008875:Middle Aged; D011013:Pneumonectomy; D011859:Radiography; D017565:Sarcoidosis, Pulmonary / Q000150:complications / Q000188:drug therapy* / Q000473:pathology*
D000305:Adrenal Cortex Hormones