title: HLA-A*020115 and HLA-Cw*030203 show new synonymous mutations in exon 4.
abstract: Two novel human leukocyte antigen (HLA) class I alleles, A*020115 and Cw*030203, were completely characterized by sequencing-based typing. Both present synonymous new HLA polymorphisms at exon 4. A*020115 shows a single nucleotide change regarding A*02010101 at codon 245 GCG > GCC). In contrast, Cw*030203 differs from Cw*030202 in a point mutation at codon 271 (ACC > ACT).
authors.affiliation: Departamento de Histocompatibilidad, Centro de Transfusión de la Comunidad de Madrid, 20832 Madrid, Spain. abalas.trans@salud.madrid.org
authors.forename: A
authors.initials: A
authors.lastname: Balas
authors.forename: L
authors.initials: L
authors.lastname: Bustamante
authors.forename: F
authors.initials: F
authors.lastname: García-Sánchez
authors.forename: J L
authors.initials: JL
authors.lastname: Vicario
mesh_terms: D000483:Alleles; D001483:Base Sequence; D005091:Exons; D015234:HLA-A Antigens / Q000235:genetics*; D015236:HLA-C Antigens / Q000235:genetics*; D006801:Humans; D008969:Molecular Sequence Data; D017354:Point Mutation; D020641:Polymorphism, Single Nucleotide
chemical_list: D015234:HLA-A Antigens; D015236:HLA-C Antigens