title: Asymmetric intermolecular heck-type reaction of acyclic alkenes via oxidative palladium(II) catalysis.
abstract: Herein, we report an asymmetric intermolecular Heck-type reaction of acyclic alkenes by using a palladium-pyridinyl oxazoline diacetate complex under oxidative palladium(II) catalysis conditions. A premade palladium-ligand complex afforded higher enantioselectivities than a corresponding premixed palladium-ligand system, while offering enhanced asymmetric induction when compared to known intermolecular Heck-type protocols.
authors.affiliation: Loker Hydrocarbon Research Institute, Department of Chemistry, University of Southern California, Los Angeles, California 90089-1661, USA.
authors.forename: Kyung Soo
authors.initials: KS
authors.lastname: Yoo
authors.forename: Chan Pil
authors.initials: CP
authors.lastname: Park
authors.forename: Cheol Hwan
authors.initials: CH
authors.lastname: Yoon
authors.forename: Satoshi
authors.initials: S
authors.lastname: Sakaguchi
authors.forename: Justin
authors.initials: J
authors.lastname: O'Neill
authors.forename: Kyung Woon
authors.initials: KW
authors.lastname: Jung
mesh_terms: D000475:Alkenes / Q000138:chemical synthesis / Q000737:chemistry*; D002384:Catalysis; D018360:Crystallography, X-Ray; D003500:Cyclization; D008024:Ligands; D008958:Models, Molecular; D015394:Molecular Structure; D010084:Oxidation-Reduction; D010165:Palladium / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D000475:Alkenes; D008024:Ligands; D010165:Palladium