Intraocular pressure correlated with arterial blood pressure: the beijing eye study.
OBJECTIVE
To assess the relation of arterial blood pressure (BP) and intraocular pressure (IOP) in an adult population not using glaucoma medications.


METHODS
Cross-sectional population-based study.


METHODS
The Beijing Eye Study 2006, a population-based, cross-sectional cohort study, included 3,253 subjects (age, 45 years or more). The mean age was 60.4 +/- 10.1 years. Seated BP and applanation tonometric IOP were measured, and their relation was assessed in regression models.


RESULTS
After exclusion of subjects who had closed anterior chamber angles and an IOP of more than 21 mm Hg or who were receiving topical antiglaucomatous treatment, the study included 2,981 subjects. In multivariate regression analysis, IOP was correlated significantly with systolic BP (P < .001; 95% confidence interval [CI], 0.011 to 0.022), diastolic BP (P < .001; 95% CI, 0.008 to 0.029), central corneal thickness (P < .001; 95% CI, 0.031 to 0.037), and myopic refractive error (P = .006; 95% CI, -0.103 to -0.015). Neither age (P = .17) nor body mass index (P = .20) were significantly associated with IOP.


CONCLUSIONS
IOP is associated significantly with systolic and diastolic BP.
Xu
Liang
L
Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Capital University of Medical Science, Beijing, China.
Wang
Han
H
Wang
Yaxing
Y
Jonas
Jost B
JB
D000368:Aged; D000369:Aged, 80 and over; D001794:Blood Pressure / Q000502:physiology*; D001795:Blood Pressure Determination; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D007429:Intraocular Pressure / Q000502:physiology*; D008297:Male; D008875:Middle Aged; D011187:Posture; D014065:Tonometry, Ocular