Progressive multifocal leukoencephalopathy from JC virus in a patient with advanced mycosis fungoides.
Progressive multifocal leukoencephalopathy is a central nervous system disease due to reactivation of the human polyoma JC virus in immunocompromised patients. Advanced mycosis fungoides patients are intrinsically immunosuppressed and susceptible to infections, but only rarely have been reported to develop progressive multifocal leukoencephalopathy. We report a case of progressive multifocal leukoencephalopathy developing in an advanced mycosis fungoides patient without prior history of immunosuppressive therapy.
Lee
Jin
J
Department of Dermatology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Richardson
Stephen K
SK
Melhem
Elias R
ER
Rook
Alain H
AH
Kim
Ellen J
EJ
D017809:Fatal Outcome; D006801:Humans; D007968:Leukoencephalopathy, Progressive Multifocal / Q000150:complications* / Q000175:diagnosis; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009182:Mycosis Fungoides / Q000150:complications* / Q000503:physiopathology; D012878:Skin Neoplasms / Q000150:complications*