The lack of endothelization after drug-eluting stent implantation as a cause of fatal late stent thrombosis.
The authors present a fatal case of late thrombosis of paclitaxel-eluting stent implanted in the left main stem occurring 6 months after the procedure and 3 weeks after the cessation of clopidogrel. An autopsy has shown the lack of endothelization of deployed stent.
Jakabcin
Jozef
J
Department of Cardiology, Masaryk hospital Usti nad Labem, Socialni pece 3316/12A, 401 13, Usti nad Labem, Czech Republic. jozef.jakabcin@mnul.cz
Bystron
Marian
M
Spacek
Radim
R
Veselka
Josef
J
Kvasnak
Martin
M
Kala
Petr
P
Malý
Jaroslav
J
Cervinka
Pavel
P
D015906:Angioplasty, Balloon, Coronary / Q000009:adverse effects / Q000295:instrumentation*; D001344:Autopsy; D002317:Cardiovascular Agents / Q000008:administration & dosage*; D000077144:Clopidogrel; D017023:Coronary Angiography; D054855:Drug-Eluting Stents; D042783:Endothelial Cells / Q000473:pathology*; D017809:Fatal Outcome; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000000981:diagnostic imaging / Q000628:therapy*; D017239:Paclitaxel / Q000008:administration & dosage*; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use; D011474:Prosthesis Design; D013927:Thrombosis / Q000209:etiology* / Q000473:pathology; D013988:Ticlopidine / Q000031:analogs & derivatives / Q000627:therapeutic use; D016896:Treatment Outcome
D002317:Cardiovascular Agents; D010975:Platelet Aggregation Inhibitors; D000077144:Clopidogrel; D013988:Ticlopidine; D017239:Paclitaxel