title: Analysis of the potential association of implant stability, laboratory, and image-based measures used to assess osteotomy sites: early versus delayed loading.
abstract: BACKGROUND
  During the assessments made at presurgical, surgical, and follow-up phases, the clinician may benefit from a wide array of clinical and/or image-based measures. Because analysis of the potential associations among the various measures could improve the evaluation process for dental implants, this study attempted to determine the potential correlations among peri-implant sulcus fluid (PISF) volume, implant stability, nitric oxide content of PISF, and marginal bone loss.
  
  
  METHODS
  Seventeen completely edentulous patients seeking prosthetic rehabilitation were included. Two ball attachment mandibular overdentures were given to all patients, and early- (N = 18) and delayed-loaded (N = 16) dental implants were compared during 24-weeks of follow-up. Resonance frequency analysis (RFA), marginal bone level, and PISF samples were taken for all dental implants.
  
  
  RESULTS
  A consistent and negative correlation was observed between RFA measurements and marginal bone level, whereas some correlations also existed between RFA and PISF volume. The pattern of loading seemed to affect the relationship between RFA measurements and marginal bone level and, to a limited extent, the association between PISF volume and nitrite levels.
  
  
  CONCLUSIONS
  Where the potential associations among various implant-related measures are concerned, the factors that may affect such associations (e.g., healing and loading) need to be considered. Data arising from the analysis of the associations between the wide arrays of available implant-related measures may improve dental practitioners' assessment concerning endosseous dental implants.
authors.affiliation: Department of Periodontology, Faculty of Dentistry, Hacettepe University, Ankara, Turkey. ttozum@hacettepe.edu.tr
authors.forename: Tolga F
authors.initials: TF
authors.lastname: Tözüm
authors.forename: Ilser
authors.initials: I
authors.lastname: Turkyilmaz
authors.forename: Nermin
authors.initials: N
authors.lastname: Yamalik
authors.forename: Erdem
authors.initials: E
authors.lastname: Karabulut
authors.forename: Kenan
authors.initials: K
authors.lastname: Eratalay
mesh_terms: D000328:Adult; D000368:Aged; D016301:Alveolar Bone Loss / Q000000981:diagnostic imaging / Q000209:etiology; D003758:Dental Implantation, Endosseous / Q000009:adverse effects / Q000379:methods*; D017268:Dental Prosthesis Retention / Q000295:instrumentation; D019094:Dental Prosthesis, Implant-Supported; D003799:Dental Stress Analysis; D003825:Denture, Complete, Immediate; D003826:Denture, Complete, Lower; D003828:Denture, Overlay; D005260:Female; D005883:Gingival Crevicular Fluid / Q000737:chemistry / Q000378:metabolism; D006801:Humans; D008297:Male; D008875:Middle Aged; D009066:Mouth, Edentulous / Q000534:rehabilitation; D009569:Nitric Oxide / Q000032:analysis; D010027:Osteotomy / Q000009:adverse effects / Q000379:methods; D017063:Outcome Assessment, Health Care / Q000379:methods; D019252:Radiography, Dental, Digital; D018709:Statistics, Nonparametric; D013997:Time Factors; D014732:Vibration
chemical_list: D009569:Nitric Oxide