Detection of human bocavirus in children hospitalized because of acute gastroenteritis.
The idea that human bocavirus (hBoV) infection possibly plays a role in gastroenteritis has been suggested because of the frequent manifestation of gastrointestinal symptoms. The purpose of this study was to investigate the prevalence of hBoV in children with gastroenteritis. We studied the etiologic agents in 962 children hospitalized with gastroenteritis. Viral etiologic agents were detected by enzyme-linked immunosorbent assay or reverse-transcriptase polymerase chain reaction. A viral agent was found in 44.4% of the study population: rotavirus, norovirus, adenovirus, and astrovirus were detected in 25.7%, 13.7%, 3.0%, and 1.1% of the study population, respectively; hBoV was detected in 0.8%, which suggests that it might play a minor role in gastroenteritis.
Lee
Jae In
JI
Department of Virus Research, Seoul Health-Environmental Research Center, Sanggyepaik Hospital, Seoul, Korea.
Chung
Ju-Young
JY
Han
Tae Hee
TH
Song
Mi-Ok
MO
Hwang
Eung-Soo
ES
D000208:Acute Disease; D052660:Bocavirus / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*; D004797:Enzyme-Linked Immunosorbent Assay; D005243:Feces / Q000821:virology; D005260:Female; D005759:Gastroenteritis / Q000453:epidemiology / Q000821:virology; D006760:Hospitalization; D006801:Humans; D007723:Korea / Q000453:epidemiology; D008297:Male; D010322:Parvoviridae Infections / Q000453:epidemiology / Q000821:virology; D015995:Prevalence; D020133:Reverse Transcriptase Polymerase Chain Reaction; D012621:Seasons; D014777:Virus Diseases / Q000453:epidemiology / Q000821:virology; D014780:Viruses / Q000145:classification / Q000235:genetics / Q000302:isolation & purification