Plastic processes in the dentate gyrus: a computational perspective.
The dentate gyrus has the capacity for numerous types of synaptic plasticity that use diverse mechanisms and are thought essential for the storage of information in the hippocampus. Here we review the various forms of synaptic plasticity that involve afferents and efferents of the dentate gyrus, and, from a computational perspective, relate how these plastic processes might contribute to sparse, orthogonal encoding, and the selective recall of information within the hippocampus.
Derrick
Brian E
BE
Department of Biology, The Cajal Neuroscience Research Institute, The University of Texas at San Antonio, TX 78249-0662, USA. bderrick@utsa.edu
D000818:Animals; D003198:Computer Simulation; D018891:Dentate Gyrus / Q000166:cytology / Q000502:physiology*; D008959:Models, Neurological; D009473:Neuronal Plasticity / Q000502:physiology*