A [3 + 3] annelation approach to (+)-rhopaloic acid B.
A general and enantiospecific [3 + 3] reaction toward functionalized pyrans is reported that has been employed in the first enantioselective synthesis of (+)-rhopaloic acid B.
Brioche
Julien C R
JC
Department of Chemistry, University of Sheffield, Brook Hill, Sheffield S3 7HF, United Kingdom.
Goodenough
Katharine M
KM
Whatrup
David J
DJ
Harrity
Joseph P A
JP
D000143:Acids / Q000737:chemistry*; D004852:Epoxy Compounds / Q000737:chemistry; D015394:Molecular Structure; D011714:Pyrans / Q000737:chemistry*
D000143:Acids; D004852:Epoxy Compounds; D011714:Pyrans; C523744:rhopaloic acid B