Chromatographic methods for the simultaneous determination of mycotoxins and their conjugates in cereals.
About 300-400 mycotoxins are known today. To some extent these compounds show very different physicochemical properties, which led to a vast quantity of analytical methods for single toxins or certain classes of mycotoxins in a variety of matrices. Due to synergistic effects of co-occurring toxins, endeavors have been made to simultaneously detect and quantify several classes of mycotoxins. This paper discusses several of the published LC-MS/MS multi-mycotoxin-methods and also introduces a new method, which allows the concurrent detection and quantification of 90 major mycotoxins and other secondary fungal metabolites in cereals. Even more, known plant derived metabolites of mycotoxins, like zearalenone-4-glucoside or deoxynivalenol-3-glucoside are included in this method. The significance of mycotoxin conjugates is briefly discussed as well.
Berthiller
Franz
F
Christian Doppler Laboratory for Mycotoxin Research, Department of Agrobiotechnology (IFA-Tulln), University of Natural Resources and Applied Life Sciences, Vienna, Konrad Lorenz Strasse 20, 3430 Tulln, Austria.
Sulyok
Michael
M
Krska
Rudolf
R
Schuhmacher
Rainer
R
D002853:Chromatography, Liquid / Q000379:methods*; D002523:Edible Grain / Q000737:chemistry* / Q000382:microbiology; D005506:Food Contamination / Q000032:analysis*; D005516:Food Microbiology; D013058:Mass Spectrometry / Q000379:methods*; D009183:Mycotoxins / Q000032:analysis*
D009183:Mycotoxins