Convergent extension and the hexahedral cell.
During development, embryonic cells sculpt three-dimensional tissues. Although cell polarity is commonly analysed along one, and sometimes two, dimensions, this perspective illustrates how higher-order cell polarity regulates convergent extension - the coordinated cell rearrangement that produces solid tissue elongation.
Green
Jeremy B A
JB
Department of Craniofacial Development, King's College London, Guys Tower Floor 27, London SE1 9RT, UK. jeremy.green@kcl.ac.uk
Davidson
Lance A
LA
D000818:Animals; D002465:Cell Movement / Q000502:physiology*; D016764:Cell Polarity; D048430:Cell Shape; D053595:Embryonic Stem Cells / Q000166:cytology / Q000502:physiology; D005353:Fibronectins / Q000378:metabolism; D006801:Humans; D009024:Morphogenesis
D005353:Fibronectins