title: Biomechanical comparison of a fully threaded, variable pitch screw and a partially threaded lag screw for internal fixation of Type II dens fractures.
abstract: METHODS
  Stiffness and load to failure were studied in a human cadaver model of Type II odontoid fractures stabilized with either a single partially threaded lag screw and washer or a headless fully threaded variable pitch screw.
  
  
  OBJECTIVE
  To determine whether a headless fully threaded variable pitch screw provides biomechanically superior fixation of Type II odontoid fractures in comparison with a partially threaded, cannulated lag screw and washer.
  
  
  BACKGROUND
  Surgical treatment of Anderson and D'Alonzo Type II odontoid fractures is often performed using a partially threaded cannulated screw and washer. Reported clinical failure rates of this construct are as high as 20%. This technique requires perforation of the cortex of the tip of the dens, placing the brainstem and vertebrobasilar circulation at risk. A headless fully threaded variable pitch screw has not been described for this application.
  
  
  METHODS
  A transverse osteotomy was created at the base of the dens in 16 human cadaver C2 specimens and stabilized using either a headless fully threaded variable pitch screw or a partially threaded cannulated lag screw and washer. Specimens were loaded to failure under a static, posteriorly directed force applied to the surface of the dens. Stiffness and load to failure were measured and the mode of failure for each specimen was determined.
  
  
  RESULTS
  Stiffness and load to failure were greater for the headless, fully threaded variable pitch screw compared with the partially threaded lag screw and washer. The mode of failure for all specimens was via anterior screw cut-out at the C2 vertebral body.
  
  
  CONCLUSIONS
  A headless, fully threaded variable pitch screw was biomechanically favorable in comparison with a partially threaded lag screw and washer in this cadaver model of Type II dens fractures. The mode of failure at the C2 vertebral body may have important implications for further improvements in construct strength.
authors.affiliation: Department of Orthopedics and Rehabilitation, Oregon Health and Science University, Portland, OR 97239-3098, USA.
authors.forename: William
authors.initials: W
authors.lastname: Magee
authors.forename: Werner
authors.initials: W
authors.lastname: Hettwer
authors.forename: Mohammed
authors.initials: M
authors.lastname: Badra
authors.forename: Brian
authors.initials: B
authors.lastname: Bay
authors.forename: Robert
authors.initials: R
authors.lastname: Hart
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001863:Bone Screws; D002102:Cadaver; D004548:Elasticity; D005260:Female; D005593:Fracture Fixation, Internal / Q000295:instrumentation*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009809:Odontoid Process / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000601:surgery*; D011474:Prosthesis Design; D011475:Prosthesis Failure; D011859:Radiography; D016103:Spinal Fractures / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000601:surgery*; D016474:Weight-Bearing