title: Validation and global uncertainty of a gas chromatographic with mass spectrometry method for fenamidone analysis in grapes and wines.
abstract: Fenamidone is an imidazolinone fungicide recently introduced in viticulture practices. This work reports the validation and assessment of global uncertainty of a gas chromatographic with mass spectrometry method to analyze fenamidone in grapes and wines. This method consists in a simple and fast liquid-liquid extraction step followed by chromatographic determination. Limits of detection for fenamidone in grapes and wines were, respectively, 0.05 mg/kg and 0.06 mg/L, precision was below 9.4% and average recovery was 89 +/- 5%. In the concentration range from 0.05 to 1.00 mg/kg (or mg/L) of fenamidone, global uncertainty calculated following the EURACHEM/CITAC rules, and also by the Horwitz function, was below 25%. The EURACHEM/CITAC global uncertainty budget used gave lower estimates than those obtained from the Horwitz function.
authors.affiliation: LEPAE-DEQ, Faculdade de Engenharia da Universidade do Porto, Porto, Portugal.
authors.forename: Susana de Melo
authors.initials: Sde M
authors.lastname: Abreu
authors.forename: Paulo
authors.initials: P
authors.lastname: Herbert
authors.forename: Pierluigi
authors.initials: P
authors.lastname: Caboni
authors.forename: Paolo
authors.initials: P
authors.lastname: Cabras
authors.forename: Arminda
authors.initials: A
authors.lastname: Alves
authors.forename: Vincenzo Luigi
authors.initials: VL
authors.lastname: Garau
mesh_terms: D003257:Consumer Product Safety; D004350:Drug Residues / Q000032:analysis*; D005659:Fungicides, Industrial / Q000032:analysis*; D008401:Gas Chromatography-Mass Spectrometry / Q000592:standards*; D006801:Humans; D048288:Imidazolines / Q000032:analysis*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D027843:Vitis / Q000737:chemistry*; D014920:Wine / Q000032:analysis*
chemical_list: D005659:Fungicides, Industrial; D048288:Imidazolines