title: [Extramammary Paget's disease of the scrotum: report of 79 cases].
abstract: OBJECTIVE
  To investigate the clinicopathologic feature and treatment result as well as prognosis of Paget's disease of the scrotum.
  
  
  METHODS
  The data of 79 patients with Paget's disease of the scrotum confirmed pathologically from 1993 to 2004 were retrospectively analyzed. The median age of these patients was 62.3 years. The median duration of the disease was 3 years and 7 months. Locally extensive excision and intra-operative frozen section analysis of resection margin were performed in 78 patients. Inguinal and iliac radical lymphadenectomy was done in 7 patients with inguinal lymph node metastasis.
  
  
  RESULTS
  Local recurrence developed in 9 patients, and 3 patients died of the disease during follow-up.
  
  
  CONCLUSIONS
  The prognosis of Paget's disease of the scrotum after surgical resection is good. To highly watch out for the disease, to perform histological examination and surgical resection as early as possible are keys to control it successfully.
authors.affiliation: Department of Urology, Huashan Hospital, Fudan University, Shanghai, China.
authors.forename: Ke
authors.initials: K
authors.lastname: Xu
authors.forename: Qiang
authors.initials: Q
authors.lastname: Ding
authors.forename: Jiang
authors.initials: J
authors.lastname: Yu
authors.forename: Jie
authors.initials: J
authors.lastname: Zheng
authors.forename: Zu-jun
authors.initials: ZJ
authors.lastname: Fang
authors.forename: Yuan-fang
authors.initials: YF
authors.lastname: Zhang
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D005500:Follow-Up Studies; D005834:Genital Neoplasms, Male / Q000473:pathology / Q000601:surgery*; D006801:Humans; D007264:Inguinal Canal; D008197:Lymph Node Excision; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D010145:Paget Disease, Extramammary / Q000473:pathology / Q000601:surgery*; D011379:Prognosis; D012189:Retrospective Studies; D012611:Scrotum / Q000473:pathology / Q000601:surgery*; D016019:Survival Analysis