Inhibitory and facilitatory effect of two related peptides on extinction of avoidance behavior.
The polypeptide chain which constitutes the first ten amino acids of the ACTH molecule inhibits extinction of a shuttle-box avoidance response. If the phenylalanine molecule in the 7th position of this peptide is replaced by its dextrorotatory form, extinction is facilitated.
Bohus
B
B
De Wied
D
D