title: Predictive factors for ambulation in stroke patients in the rehabilitation setting: a multivariate analysis.
abstract: OBJECTIVE
  The purpose of this study was to investigate predictive factors for ambulatory recovery in stroke patients undergoing rehabilitation.
  
  
  METHODS
  One hundred and eight-five first-stroke hemiplegics, admitted to an inpatient stroke rehabilitation program, were consecutively recruited to the study. Functional status at admission and discharge was evaluated by the Functional Independence Measure (FIM) and its motor component (motFIM), the upper and lower Motricity Index (upMI and lowMI), and the Trunk Control Test (TCT). The outcome variable was the Functional Ambulation Classification (FAC) score, assessed at discharge from rehabilitation. Multivariate analysis was used to assess the relationships between functional outcome (FAC), and the predictive variables.
  
  
  RESULTS
  Up- and lowMI, FIM and motFIM, TCT and age at admission were significantly related to ambulatory recovery at discharge. Logistic regression analysis showed that the independent variables related to FAC were age, TCT and FIM: the model correctly allocated 86 out of 100 cases in the construction set and 76% of cases in the validation set. The ROC curve with logistic function output as the risk factor afforded very good accuracy (ROC area=0.94), sensitivity=86.5% and specificity=85.4%.
  
  
  CONCLUSIONS
  Our results show that age and level of motor and functional impairment measured at baseline are significant predictors of ambulatory outcome. These findings promise to be of interest in goal optimization in the rehabilitation setting.
authors.affiliation: Department of Rehabilitation Medicine, Unit of Rehabilitation, University of Padova, School of Medicine, Padova, Italy. stef.masiero@unipd.it
authors.forename: Stefano
authors.initials: S
authors.lastname: Masiero
authors.forename: Renato
authors.initials: R
authors.lastname: Avesani
authors.forename: Mario
authors.initials: M
authors.lastname: Armani
authors.forename: Postal
authors.initials: P
authors.lastname: Verena
authors.forename: Mario
authors.initials: M
authors.lastname: Ermani
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D015331:Cohort Studies; D051341:Dependent Ambulation / Q000502:physiology; D005260:Female; D020233:Gait Disorders, Neurologic / Q000209:etiology / Q000503:physiopathology* / Q000534:rehabilitation*; D006429:Hemiplegia / Q000209:etiology / Q000503:physiopathology / Q000534:rehabilitation; D006801:Humans; D008297:Male; D008875:Middle Aged; D009043:Motor Activity / Q000502:physiology; D015999:Multivariate Analysis; D011237:Predictive Value of Tests; D020127:Recovery of Function / Q000502:physiology*; D012307:Risk Factors; D012720:Severity of Illness Index; D020521:Stroke / Q000150:complications / Q000503:physiopathology*; D000071939:Stroke Rehabilitation; D016896:Treatment Outcome