title: [Hormone replacement Up-to-date. Effect of estrogen therapy (EP) and estrogen-progestogen therapy (EPT) on the bone metabolism].
abstract: Estrogen depletion after menopause become involved with postmenopausal bone loss, therefore ET (estrogen therapy) and EPT (estrogen-progestogen therapy) have been considered as first-line therapy for postmenopausal osteopenia and osteoporosis. However, after WHI (Women's Health Initiative) reports, use of estrogen for treatment of osteopenia and osteoporosis is limited. Because estrogen plays indispensable roles in maintaining female physiological functions including bone metabolism, use of estrogens would elicit much benefits when administered properly.
authors.affiliation: Hirosaki university school of medicine, Department of Obstetrics and Gynecology, Japan.
authors.forename: Ryousuke
authors.initials: R
authors.lastname: Taniguchi
authors.forename: Tsuyoshi
authors.initials: T
authors.lastname: Higuchi
authors.forename: Hideki
authors.initials: H
authors.lastname: Mizunuma
mesh_terms: D015914:Estrogen Replacement Therapy; D005260:Female; D020249:Hormone Replacement Therapy; D006801:Humans; D015663:Osteoporosis, Postmenopausal / Q000188:drug therapy*; D045167:Progesterone Congeners / Q000627:therapeutic use*
chemical_list: D045167:Progesterone Congeners