[Correlation of hybrid II capture cytologic exam in diagnosis of cervical lesions related to HPV].
OBJECTIVE
The aim of the present study was confront the results of the cytological examination with hybrid capture II in the diagnosis of induced cervical intraepithelial lesion-HPV, correlating the cytological findings with biomoleculares.


METHODS
The research was carried through in a group of 160 sexually active women who had espontaneamente looked its gynecologists for consultation of routine, having been submitted to the collection of cervicovaginal material for cytology and for examination of hybrid capture II in the Centro de Patologia Clínica and the Hospital e Maternidade Promater, in the city of the Natal-RN.


RESULTS
The results had shown to relatively high numbers of positive cases for HPV using hybrid capture II (41.87%) and the cytology (23.75%). The agreement between the two studied methods relatively was raised (59.38%). It was evident also that the viruses with high oncogênico potential had presented found in the compatible cytology with Lesion of low risk (11.88%), followed of Lesion of high risk (NIC II and III); already the viruses with low oncogênico potential were more associates the Lesion of low risk (6.25%), followed of Lesion of high risk.


CONCLUSIONS
The cytology, exactly with its limitations, is an important method in the detention of attributable patologias to the HPV, emphasizing that the molecular method comes to complement it and to consolidate the cytological findings.
Saturnino
Ana Conceição Ribeiro Dantas
AC
Departamento de Análises Clínicas e Toxicológicas da Universidade Federal do Rio Grande do Norte. sassuana@ufrnet.br
Diniz
Veruska Cassandra
VC
Sisenando
Herbert Ary Arzabe Anteza Costa Nóbrega
HA
de Souza
Eroisa Maria Conceição Oliveira
EM
de Paiva
Magnus Sérgio Martins
MS
de Brito
Maria Helena Marques Fonseca
MH
Ramos
Eleni Souto Nóbrega
ES
D000293:Adolescent; D000328:Adult; D001706:Biopsy; D002584:Cervix Uteri / Q000473:pathology / Q000821:virology*; D015344:DNA Probes, HPV / Q000032:analysis*; D004279:DNA, Viral / Q000032:analysis*; D005260:Female; D006801:Humans; D030361:Papillomavirus Infections / Q000175:diagnosis* / Q000235:genetics; D012680:Sensitivity and Specificity; D002577:Uterine Cervical Diseases / Q000175:diagnosis* / Q000235:genetics; D002583:Uterine Cervical Neoplasms / Q000517:prevention & control; D014626:Vaginal Smears / Q000379:methods*
D015344:DNA Probes, HPV; D004279:DNA, Viral