Free serum testosterone level in male rats treated with Tribulus alatus extracts.
OBJECTIVE
The present study was undertaken to investigate the effect of Tribulus alatus extracts on free serum testosterone in male rats.


METHODS
Free serum testosterone level was measured in male rats treated with alcoholic extracts of the aerial part without fruits, fruits of Tribulus alatus and their fractions.


RESULTS
All tested extracts showed significant increase in the level of free serum testosterone when compared to that of corresponding control, p < 0.05. Statistical comparison of all groups revealed that the maximum level was found in groups treated with chloroformic and ethanolic fractions of fruits extract.


CONCLUSIONS
Tribulus alatus extract appears to possess aphrodisiac activity due to its androgen increasing property.
El-Tantawy
Walid H
WH
Drug Bioavailability Center, National Organization For Drug Control and Research, Cairo, Egypt. wldhmdy@yahoo.com
Temraz
Abeer
A
El-Gindi
Omayma D
OD
D000818:Animals; D001046:Aphrodisiacs / Q000737:chemistry / Q000494:pharmacology*; D004353:Drug Evaluation, Preclinical; D008297:Male; D010413:Penis / Q000098:blood supply; D008517:Phytotherapy; D035261:Plant Components, Aerial / Q000737:chemistry*; D010936:Plant Extracts / Q000494:pharmacology; D011897:Random Allocation; D051381:Rats; D017208:Rats, Wistar; D012726:Sexual Behavior, Animal / Q000187:drug effects*; D013739:Testosterone / Q000097:blood*; D032444:Tribulus / Q000737:chemistry*
D001046:Aphrodisiacs; D010936:Plant Extracts; D013739:Testosterone