Centrioles want to move out and make cilia.
Cilia formation in mammalian cells requires basal bodies that are either derived from centrioles that transition from their cytoplasmic role in centrosome organization or that form en masse in multiciliated cells. Several recent studies have begun to uncover the links between centriole duplication and their transformation to basal bodies.
Pearson
Chad G
CG
MCD Biology, University of Colorado, Boulder, CO 80309, USA. chad.pearson@colorado.edu
Culver
Brady P
BP
Winey
Mark
M
D000107:Acetylation; D064127:Aurora Kinases; D018797:Cell Cycle Proteins / Q000378:metabolism; D002502:Centrioles / Q000378:metabolism*; D018385:Centrosome / Q000378:metabolism; D002923:Cilia / Q000145:classification / Q000378:metabolism* / Q000502:physiology; D006801:Humans; D008869:Microtubule-Associated Proteins / Q000378:metabolism; D008954:Models, Biological; D009687:Nuclear Proteins / Q000378:metabolism; D010750:Phosphoproteins / Q000378:metabolism; D017346:Protein Serine-Threonine Kinases / Q000378:metabolism; D014404:Tubulin / Q000378:metabolism
C467559:CCP110 protein, human; D018797:Cell Cycle Proteins; D008869:Microtubule-Associated Proteins; D009687:Nuclear Proteins; D010750:Phosphoproteins; D014404:Tubulin; D064127:Aurora Kinases; D017346:Protein Serine-Threonine Kinases