title: Determination of [201Tl]Tl(III) in [201Tl]TlCl solutions using HPLC.
abstract: A high-performance liquid chromatography technique has been presented to measure the [(201)Tl]TlCl(3) impurity in [(201)Tl]TlCl radiopharmaceutical for precise determination of radiochemical purity. Diethylene tetraamine pentaacetic acid (DTPA) has been used for complete complexation of [(201)Tl]Tl(III). [(201)Tl]Tl(III)-DTPA was analyzed in the presence of [(201)Tl]Tl(I) using a cation exchange HPLC column.
authors.affiliation: Nuclear Medicine Group, Agriculture, Medicine and Industrial Research School, Nuclear Science & Technology Research Institute, Moazzen Blvd., Rajaeeshahr, PO Box 31485-498, Karaj, Iran. makhlaghi@nrcam.org
authors.forename: M
authors.initials: M
authors.lastname: Akhlaghi
authors.forename: M
authors.initials: M
authors.lastname: Kamalidehghan
authors.forename: A R
authors.initials: AR
authors.lastname: Jalilian
authors.forename: N
authors.initials: N
authors.lastname: Shadanpoor
mesh_terms: D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D004369:Pentetic Acid / Q000737:chemistry; D019275:Radiopharmaceuticals / Q000032:analysis*; D013793:Thallium / Q000032:analysis* / Q000737:chemistry
chemical_list: D019275:Radiopharmaceuticals; C027549:thallium chloride; D004369:Pentetic Acid; D013793:Thallium