title: Obstinate cough as a sole presenting symptom of non-metastatic renal cell carcinoma.
abstract: Renal cell carcinoma (RCC) causes many kinds of symptoms such as hypercalcemia, hypertension, polycythemia and fever. Here we describe a rare case of RCC presenting with a persistent cough. After radical nephrectomy, the obstinate cough disappeared. When the tumor recurred locally, the cough also recurred. Furthermore, the cough disappeared completely again after the removal of the recurrent tumor. Although all the clinical findings suggested that the RCC caused the cough, we could not identify a specific humoral substance responsible for the cough.
authors.affiliation: Department of Urology, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo, Japan. yuhei.okubo@jfcr.or.jp
authors.forename: Yuhei
authors.initials: Y
authors.lastname: Okubo
authors.forename: Junji
authors.initials: J
authors.lastname: Yonese
authors.forename: Satoru
authors.initials: S
authors.lastname: Kawakami
authors.forename: Sinya
authors.initials: S
authors.lastname: Yamamoto
authors.forename: Yoshinobu
authors.initials: Y
authors.lastname: Komai
authors.forename: Hideki
authors.initials: H
authors.lastname: Takeshita
authors.forename: Yuichi
authors.initials: Y
authors.lastname: Ishikawa
authors.forename: Iwao
authors.initials: I
authors.lastname: Fukui
mesh_terms: D002292:Carcinoma, Renal Cell / Q000150:complications*; D003371:Cough / Q000209:etiology*; D005260:Female; D006801:Humans; D007680:Kidney Neoplasms / Q000150:complications*; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000150:complications*; D010257:Paraneoplastic Syndromes / Q000209:etiology*