title: The place of adsorption and biochromatography in extracorporeal liver support systems.
abstract: Artificial and bioartificial liver devices aim at replacing some or all liver functions in the cases of end stage or fulminant disorders. Among all of its function, liver plays a key role in detoxification of substances that are hydrosoluble or bound to albumin. In this paper, the authors first reviewed the requirements for temporary liver support, then the adsorption-based systems that can be found on the market and finally propose new applications of biochromatography using perfusion-based bioartificial systems.
authors.affiliation: Technological University of Compiègne, UMR CNRS 6600 Biomechanics and Biomedical Engineering, BP 20529, 60205 Compiègne Cedex, France. cecile@legallais@utc.fr
authors.forename: C
authors.initials: C
authors.lastname: Legallais
authors.forename: A
authors.initials: A
authors.lastname: Gautier
authors.forename: M
authors.initials: M
authors.lastname: Dufresne
authors.forename: B
authors.initials: B
authors.lastname: Carpentier
authors.forename: R
authors.initials: R
authors.lastname: Baudoin
mesh_terms: D000042:Absorption; D000818:Animals; D001709:Biotechnology / Q000379:methods / Q000639:trends; D002845:Chromatography / Q000295:instrumentation / Q000379:methods*; D006464:Hemoperfusion; D006801:Humans; D008021:Life Support Systems / Q000295:instrumentation; D019164:Liver, Artificial