title: [A case of pulmonary nocardiosis cured by early sulfamethoxazole-trimethoprim therapy].
abstract: A 46-year-old man had been given 40mg prednisolone daily for systemic lupus erythematosus. He complained of fever and general fatigue and chest computed tomography revealed wide-spread consolidation with multiple cavity formation in his left lung. Pulmonary nocardiosis was clinically suspected because we detected nocardia from Gram staining of sputum. He was cured by sulfamethoxazole-trimethoprim, Imipenem/Cilastatin, although a cavity with a slightly thickened wall in the left lung remained. Nocardia asteroides was cultured from sputum and pulmonary nocardiosis was diagnosed. The present case was pulmonary nocardiosis that spread with multiple and extensive cavity formation. A good outcome was obtained by early treatment with sulfamethoxazole-trimethoprim.
authors.affiliation: Department of Respiratory Medicine, Otsu Red Cross Hospital.
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Wada
authors.forename: Naoki
authors.initials: N
authors.lastname: Sakai
authors.forename: Yusuke
authors.initials: Y
authors.lastname: Matsui
authors.forename: Mayumi
authors.initials: M
authors.lastname: Kojima
authors.forename: Hiromichi
authors.initials: H
authors.lastname: Katakura
authors.forename: Akira
authors.initials: A
authors.lastname: Yamanaka
mesh_terms: D000890:Anti-Infective Agents / Q000627:therapeutic use*; D006801:Humans; D008171:Lung Diseases / Q000188:drug therapy* / Q000209:etiology; D008180:Lupus Erythematosus, Systemic / Q000150:complications / Q000188:drug therapy; D008181:Lupus Nephritis / Q000150:complications / Q000188:drug therapy; D008297:Male; D008875:Middle Aged; D009617:Nocardia Infections / Q000188:drug therapy* / Q000209:etiology; D009894:Opportunistic Infections / Q000188:drug therapy; D011239:Prednisolone / Q000008:administration & dosage; D016896:Treatment Outcome; D015662:Trimethoprim, Sulfamethoxazole Drug Combination / Q000627:therapeutic use*
chemical_list: D000890:Anti-Infective Agents; D015662:Trimethoprim, Sulfamethoxazole Drug Combination; D011239:Prednisolone