title: Serum sickness-like reaction to cefuroxime: a case report and review of the literature.
abstract: We report a case of a 34-year-old woman who received cefuroxime, a second-generation cephalosporin, as treatment for mastitis. She subsequently developed a serum sickness-like reaction (SSLR) with a generalized pruritic rash, joint pains, and fever. She improved upon treatment with systemic steroids. SSLR is well-described to cefaclor, a second-generation cephalosporin. However, there is a paucity of reports of SSLR to other cephalosporins such as this case.
authors.affiliation: Department of Dermatology, Baylor College of Medicine, Houston, TX, USA.
authors.forename: Rajani
authors.initials: R
authors.lastname: Katta
authors.forename: Vijayalaxmi
authors.initials: V
authors.lastname: Anusuri
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000009:adverse effects / Q000627:therapeutic use; D018771:Arthralgia / Q000139:chemically induced; D002444:Cefuroxime / Q000009:adverse effects* / Q000627:therapeutic use; D005076:Exanthema / Q000139:chemically induced; D005260:Female; D005334:Fever / Q000139:chemically induced; D006801:Humans; D008413:Mastitis / Q000188:drug therapy; D011537:Pruritus / Q000139:chemically induced; D012713:Serum Sickness / Q000139:chemically induced* / Q000473:pathology
chemical_list: D000900:Anti-Bacterial Agents; D002444:Cefuroxime