title: trans-Cyclohexane-1,2-diamine is a weak director of absolute helicity in chiral nickel-salen complexes.
abstract: The interconversion between helical diastereomers of nickel-salen-based foldamers can be observed on a NMR time scale. Such complexes provide quantitative information about the propensity of different elements of central chirality to control the absolute sense of folding. trans-Cyclohexane-1,2-diamine-a common component of chiral salen catalysts-is a surprisingly weak director of absolute helicity in nickel-salen foldamers. Implications for asymmetric catalysis are discussed.
authors.affiliation: Brown Laboratories, Department of Chemistry and Biochemistry, University of Delaware, Newark, Delaware 19716, USA.
authors.forename: Zhenzhen
authors.initials: Z
authors.lastname: Dong
authors.forename: Glenn P A
authors.initials: GP
authors.lastname: Yap
authors.forename: Joseph M
authors.initials: JM
authors.lastname: Fox