title: Prevalence and risk factors of peripheral arterial disease in diabetic patients over 50 years old in China.
abstract: OBJECTIVE
  To investigate the prevalence of peripheral arterial disease (PAD) in China type 2 diabetic patients and to demonstrate the relationships between putative risk factors and PAD.
  
  
  METHODS
  In total 1,397 type 2 diabetic patients aged 50 years and older were enrolled and determined ankle-brachial index (ABI) and brachial-ankle pulse wave velocity (baPWV) in 15 Class III Grade A hospitals in 7 major cities of China.
  
  
  RESULTS
  Mean patient age was 63.7 +/- 8.2 years and mean duration of diabetes mellitus was 9.39 +/- 7.4 years. Two hundreds and seventy-two (19.47%) patients were diagnosed as PAD by ABI < 0.9, 122 (18.37%) in male and 150 (20.46%) in female. PAD patients had a significantly longer duration of diabetes mellitus, higher hemoglobin A1c, and a significantly lower mean body mass index than non-PAD ones. Aging, smoking, and systolic blood pressure were found to be positively related with the prevalence of PAD. In terms of lipid profiles, no variable was found to relate with PAD. Notably, baPWV showed as the same significant guiding index for PAD, almost matched with ABI.
  
  
  CONCLUSIONS
  PAD is a common complication in China type 2 diabetic patients. Therefore, PAD screening and treatment should be emphasized for diabetic patients with high risk factors.
authors.affiliation: Department of Vascular Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730. guanheng3@hotmail.com
authors.forename: Heng
authors.initials: H
authors.lastname: Guan
authors.forename: Yong-Jun
authors.initials: YJ
authors.lastname: Li
authors.forename: Zhang-Rong
authors.initials: ZR
authors.lastname: Xu
authors.forename: Guang-Wei
authors.initials: GW
authors.lastname: Li
authors.forename: Xiao-Hui
authors.initials: XH
authors.lastname: Guo
authors.forename: Zhi-Min
authors.initials: ZM
authors.lastname: Liu
authors.forename: Da-Jin
authors.initials: DJ
authors.lastname: Zou
authors.forename: Hui-Li
authors.initials: HL
authors.lastname: Xing
authors.forename: Wei
authors.initials: W
authors.lastname: Liu
authors.forename: Zheng-Yan
authors.initials: ZY
authors.lastname: Sheng
authors.forename: Hao-Ming
authors.initials: HM
authors.lastname: Tian
authors.forename: Da-Long
authors.initials: DL
authors.lastname: Zhu
authors.forename: De-Min
authors.initials: DM
authors.lastname: Yu
authors.forename: Wei-Te
authors.initials: WT
authors.lastname: Zhuang
authors.forename: Lu-Lu
authors.initials: LL
authors.lastname: Chen
authors.forename: Jian-Ping
authors.initials: JP
authors.lastname: Weng
mesh_terms: D000368:Aged; D002681:China / Q000453:epidemiology; D003925:Diabetic Angiopathies / Q000453:epidemiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D016491:Peripheral Vascular Diseases / Q000453:epidemiology*; D015995:Prevalence; D012307:Risk Factors; D014505:Urban Population / Q000706:statistics & numerical data