External ophthalmoplegia as the presenting feature of systemic amyloidosis.
BACKGROUND
Amyloidosis is a multi-system disease characterised by the intracellular deposition of beta-pleated sheets of amyloid. It can involve the eye, orbit and ocular adnexae.


METHODS
We describe a case of a 58-year-old woman presenting to the eye department with external ophthalmoplegia, including the findings of various investigations. The spectrum of ocular amyloidosis is discussed.


CONCLUSIONS
Amyloidosis may be the underlying diagnosis in some cases of external ophthalmoplegia with findings atypical to other systemic disease.
Lett
Kim Son
KS
Department of Ophthalmology, University Hospitals of Leicester, Leicester, UK.
Shah
Ameet
A
Gottlob
Irene
I
D000686:Amyloidosis / Q000150:complications* / Q000175:diagnosis; D003937:Diagnosis, Differential; D005260:Female; D005403:Fixation, Ocular; D006801:Humans; D008875:Middle Aged; D009886:Ophthalmoplegia / Q000000981:diagnostic imaging / Q000209:etiology* / Q000503:physiopathology; D014057:Tomography, X-Ray Computed