title: Centrioles want to move out and make cilia.
abstract: Cilia formation in mammalian cells requires basal bodies that are either derived from centrioles that transition from their cytoplasmic role in centrosome organization or that form en masse in multiciliated cells. Several recent studies have begun to uncover the links between centriole duplication and their transformation to basal bodies.
authors.affiliation: MCD Biology, University of Colorado, Boulder, CO 80309, USA. chad.pearson@colorado.edu
authors.forename: Chad G
authors.initials: CG
authors.lastname: Pearson
authors.forename: Brady P
authors.initials: BP
authors.lastname: Culver
authors.forename: Mark
authors.initials: M
authors.lastname: Winey
mesh_terms: D000107:Acetylation; D064127:Aurora Kinases; D018797:Cell Cycle Proteins / Q000378:metabolism; D002502:Centrioles / Q000378:metabolism*; D018385:Centrosome / Q000378:metabolism; D002923:Cilia / Q000145:classification / Q000378:metabolism* / Q000502:physiology; D006801:Humans; D008869:Microtubule-Associated Proteins / Q000378:metabolism; D008954:Models, Biological; D009687:Nuclear Proteins / Q000378:metabolism; D010750:Phosphoproteins / Q000378:metabolism; D017346:Protein Serine-Threonine Kinases / Q000378:metabolism; D014404:Tubulin / Q000378:metabolism
chemical_list: C467559:CCP110 protein, human; D018797:Cell Cycle Proteins; D008869:Microtubule-Associated Proteins; D009687:Nuclear Proteins; D010750:Phosphoproteins; D014404:Tubulin; D064127:Aurora Kinases; D017346:Protein Serine-Threonine Kinases