New calogenin glycosides from Hoodia gordonii.
Ten new pregnane glycosides (1, 3-11) were isolated from organic extracts of aerial parts of Hoodia gordonii, which is sold as an appetite suppressant herbal supplement. The aglycone was identified as calogenin, based on the spectroscopic data of products obtained upon chemical and enzymatic degradation of parent glycoside. The structures of the glycosides were established by chemical degradation studies and extensive spectroscopic techniques that included one-dimensional and two-dimensional NMR.
Pawar
Rahul S
RS
National Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, University of Mississippi, University, MS 38677, USA.
Shukla
Yatin J
YJ
Khan
Ikhlas A
IA
D029062:Apocynaceae / Q000737:chemistry*; D006027:Glycosides / Q000737:chemistry* / Q000302:isolation & purification; D013058:Mass Spectrometry; D015394:Molecular Structure; D010936:Plant Extracts / Q000737:chemistry; D011278:Pregnanes / Q000737:chemistry* / Q000302:isolation & purification
D006027:Glycosides; D010936:Plant Extracts; D011278:Pregnanes