title: Reliable evidence of safety and efficacy of elderly patients in randomized clinical trials still needed.
authors.forename: Sheila M
authors.initials: SM
authors.lastname: Crean
authors.forename: Matthew W
authors.initials: MW
authors.lastname: Reynolds
authors.forename: Christin A
authors.initials: CA
authors.lastname: Dematto
mesh_terms: D000368:Aged; D017326:Clinical Trials, Phase III as Topic; D015986:Confounding Factors, Epidemiologic; D006801:Humans; D009369:Neoplasms / Q000401:mortality / Q000628:therapy*; D010358:Patient Participation; D018579:Patient Selection; D016032:Randomized Controlled Trials as Topic; D012107:Research Design; D036302:Therapeutic Human Experimentation / Q000941:ethics