title: Implantable cardioverter-defibrillator infection due to Scedosporium apiospermum.
abstract: We report a case of implantable cardioverter-defibrillator infection due to Scedosporium apiospermum. This infection persisted despite systemic antifungal treatment with voriconazole and was controlled after removal of the foreign device and replacement of the involved tricuspid valve. This case underscores the importance of a combined surgical and medical approach for this complicated infection. Scedosporium species should be considered in the differential diagnosis of cardiac or intravascular device-related infections.
authors.affiliation: Division of Infectious Diseases, Department of Internal Medicine, University of Texas Medical Branch, 301 University Boulevard, Route 0435, Galveston, TX 77555-0435, USA.
authors.forename: Bilal
authors.initials: B
authors.lastname: Sarvat
authors.forename: Juan C
authors.initials: JC
authors.lastname: Sarria
mesh_terms: D000935:Antifungal Agents / Q000627:therapeutic use; D009202:Cardiomyopathies / Q000209:etiology / Q000628:therapy; D017147:Defibrillators, Implantable / Q000009:adverse effects*; D020878:Device Removal; D048909:Diabetes Complications; D004696:Endocarditis / Q000382:microbiology / Q000628:therapy; D009877:Endophthalmitis / Q000382:microbiology / Q000628:therapy; D006801:Humans; D008172:Lung Diseases, Fungal / Q000382:microbiology / Q000628:therapy; D008297:Male; D008875:Middle Aged; D008271:Mycetoma / Q000382:microbiology* / Q000628:therapy; D016459:Prosthesis-Related Infections / Q000382:microbiology* / Q000628:therapy; D021681:Scedosporium / Q000302:isolation & purification*
chemical_list: D000935:Antifungal Agents