Validation and global uncertainty of a gas chromatographic with mass spectrometry method for fenamidone analysis in grapes and wines.
Fenamidone is an imidazolinone fungicide recently introduced in viticulture practices. This work reports the validation and assessment of global uncertainty of a gas chromatographic with mass spectrometry method to analyze fenamidone in grapes and wines. This method consists in a simple and fast liquid-liquid extraction step followed by chromatographic determination. Limits of detection for fenamidone in grapes and wines were, respectively, 0.05 mg/kg and 0.06 mg/L, precision was below 9.4% and average recovery was 89 +/- 5%. In the concentration range from 0.05 to 1.00 mg/kg (or mg/L) of fenamidone, global uncertainty calculated following the EURACHEM/CITAC rules, and also by the Horwitz function, was below 25%. The EURACHEM/CITAC global uncertainty budget used gave lower estimates than those obtained from the Horwitz function.
Abreu
Susana de Melo
Sde M
LEPAE-DEQ, Faculdade de Engenharia da Universidade do Porto, Porto, Portugal.
Herbert
Paulo
P
Caboni
Pierluigi
P
Cabras
Paolo
P
Alves
Arminda
A
Garau
Vincenzo Luigi
VL
D003257:Consumer Product Safety; D004350:Drug Residues / Q000032:analysis*; D005659:Fungicides, Industrial / Q000032:analysis*; D008401:Gas Chromatography-Mass Spectrometry / Q000592:standards*; D006801:Humans; D048288:Imidazolines / Q000032:analysis*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D027843:Vitis / Q000737:chemistry*; D014920:Wine / Q000032:analysis*
D005659:Fungicides, Industrial; D048288:Imidazolines