title: Prolonged immunosuppression and tumor induction by a chemical carcinogen injected at birth.
abstract: The injection of 60 micrograms of 9,10-dimethyl-1,2-benzanthracene into newborn mice gave rise to a very high incidence of malignant thymomas. The tumor incidence was directly related to the dose of the carcinogen. The neonatal injection of the carcinogen also resulted in a depression in the immune response when the animals were challenged with an antigert as early as 4 weeks or as late as 11 weeks after administration of the carcinogen.
authors.forename: J K
authors.initials: JK
authors.lastname: Ball
authors.forename: N R
authors.initials: NR
authors.lastname: Sinclair
authors.forename: J A
authors.initials: JA
authors.lastname: McCarter