Evaluation of the association of Bartonella species, feline herpesvirus 1, feline calicivirus, feline leukemia virus and feline immunodeficiency virus with chronic feline gingivostomatitis.
Gingivostomatitis (GS) is a significant condition in cats because of oral discomfort and associated periodontal disease. Several infectious agents have been associated with the presence of GS, but a causal relationship is unclear. The cats in this study were housed together, had a history of flea exposure, and were vaccinated with a modified live FVRCP product. There were nine cats with active GS and 36 unaffected cats at the time of sample collection. Serum was tested for feline leukemia virus (FeLV) antigen and antibodies against feline immunodeficiency virus, feline calicivirus (FCV), feline herpesvirus 1 (FHV-1), and Bartonella species (enzyme-linked immunosorbent assay and Western blot immunoassay). PCR assays for Bartonella species and FHV-1 and a reverse transcriptase PCR assay for FCV were performed on blood and throat swabs. All cats were negative for FeLV. Assay results failed to correlate to the presence of GS in the group of cats studied.
Quimby
Jessica M
JM
College of Veterinary Medicine and Biomedical Sciences, Colorado State University, 300 West Drake Road, Fort Collins, CO 80523, USA. jquimby@colostate.edu
Elston
Thomas
T
Hawley
Jennifer
J
Brewer
Melissa
M
Miller
Arianne
A
Lappin
Michael R
MR
D000818:Animals; D000914:Antibodies, Viral / Q000097:blood; D000956:Antigens, Viral / Q000302:isolation & purification; D001473:Bartonella / Q000302:isolation & purification; D017927:Calicivirus, Feline / Q000302:isolation & purification; D002371:Cat Diseases / Q000821:virology*; D002415:Cats; D002908:Chronic Disease; D016765:Coronavirus, Feline / Q000302:isolation & purification; D004797:Enzyme-Linked Immunosorbent Assay; D028301:Feline Panleukopenia Virus / Q000302:isolation & purification; D005260:Female; D005891:Gingivitis / Q000662:veterinary* / Q000821:virology*; D006564:Herpesviridae / Q000302:isolation & purification; D016089:Immunodeficiency Virus, Feline / Q000302:isolation & purification; D005256:Leukemia Virus, Feline / Q000302:isolation & purification; D008297:Male; D013280:Stomatitis / Q000662:veterinary* / Q000821:virology*
D000914:Antibodies, Viral; D000956:Antigens, Viral