title: [Electroretinography in the evaluation of vitreoretinal proliferative changes due to penetrating shell injury to the eye].
abstract: The influence of vitreoretinal proliferative changes on retinal electrogenesis and glioneuronal relationships was studied in 41 patients with penetrating shell injury to the eye. The early data of studies indicated that there is a reduction in the hanz-feldt amplitude on an electroretinogram (ERG). According to the data of optic coherent tomography (OCT), this corresponds to an exudative reactive response and to the development of vitreoretinal tractional changes in the retina in the central zone and at the site of a foreign body. Retinal electrogenetic changes were most pronounced at months 1 to 6 of a follow-up. The integral glial index was decreased and the central index of Müller's cells was drastically increased in the injured eyes. In this period, there was a reduction in an exudative response to injury and an increase in vitreoretinal proliferative changes, as evidenced by OCT. In late posttraumatic period, the injured eyes were characterized by a slow increase in the amplitude of biopotentials that did not achieve the lower normal range just 1 year or more after injuring. Late posttraumatic inhibition is likely to be caused by vitreoretinal complications of mainly dystrophic nature in the central retinal zone and at the site of fragment bedding or removed foreign body.
authors.forename: V V
authors.initials: VV
authors.lastname: Neroev
authors.forename: R A
authors.initials: RA
authors.lastname: Gundorova
authors.forename: M V
authors.initials: MV
authors.lastname: Zyeva
authors.forename: A V
authors.initials: AV
authors.lastname: Stepanov
authors.forename: I V
authors.initials: IV
authors.lastname: Tsapenko
authors.forename: I Z
authors.initials: IZ
authors.lastname: Karlova
authors.forename: T V
authors.initials: TV
authors.lastname: Nikitina
mesh_terms: D000328:Adult; D018450:Disease Progression; D004596:Electroretinography; D015807:Eye Injuries, Penetrating / Q000150:complications / Q000473:pathology / Q000503:physiopathology*; D005500:Follow-Up Studies; D006801:Humans; D008875:Middle Aged; D011379:Prognosis; D013997:Time Factors; D041623:Tomography, Optical Coherence; D015599:Trauma Severity Indices; D018630:Vitreoretinopathy, Proliferative / Q000209:etiology / Q000473:pathology / Q000503:physiopathology*