title: Aminoacidemias: effects on maze performance and cerebral serotonin.
abstract: The feeding of high dietary supplements of L-phenylalanine (7 percent) and L-leucine (7 percent) to weanling rats is associated with poor performance in a multiple-T, water-escape maze. Supplements high in L-tryptophan (5 percent), on the other hand, result in maze performance which is superior to that of controls. Adding 5 percent tryptophan to the high-phenylalanine diet reverses the behavioral deficit. The quality of maze performance correlated with the cerebral content of serotonin.
authors.forename: C M
authors.initials: CM
authors.lastname: McKean
authors.forename: S M
authors.initials: SM
authors.lastname: Schanberg
authors.forename: N J
authors.initials: NJ
authors.lastname: Giarman