[The state of ferment systems, participating in cholesterole metabolism: the influence of hepatotropic means under food hypercholesterolemia].
The studies, conducted on mice and rats with experimentally obtained hypercholesterolemia. Revealed that hepatotropic means of animal and plant origin--hepathosan, entherosan, karsil and alcohol, rich in biologically active substances, make for acceleration of cholesteroles hydroxylation in liver and increase of Hmger genes expression level up to planned indices. It was determined that hepathosan has the strongest modulating effect among hepatotropic means.
Vlasova
N A
NA
D000818:Animals; D002784:Cholesterol / Q000378:metabolism* / Q000633:toxicity; D045424:Complex Mixtures / Q000008:administration & dosage*; D019587:Dietary Supplements; D015971:Gene Expression Regulation, Enzymologic / Q000187:drug effects; D006903:Hydroxymethylglutaryl CoA Reductases / Q000096:biosynthesis*; D006937:Hypercholesterolemia / Q000139:chemically induced / Q000178:diet therapy / Q000201:enzymology*; D008297:Male; D051379:Mice; D051381:Rats