Formal DNA hydrolysis by mono- and dinuclear iron complexes.
The complexes CpFe(CO)(2)Ph and [CpFe(CO)(2)](2) cleave DNA in the presence of H2O2 or organic peroxides to give products resulting from the formal hydrolysis of the phosphodiester groups.
Shell
Thomas A
TA
Department of Chemistry, Emory University, 1515 Dickey Drive, Atlanta, Georgia 30322, USA.
Glass
Jessica E
JE
Mackey
Megan A
MA
Layman
Kathryn A
KA
Mohler
Debra L
DL
D004247:DNA / Q000737:chemistry*; D004952:Esters; D006861:Hydrogen Peroxide / Q000737:chemistry; D006868:Hydrolysis; D058085:Iron Compounds / Q000737:chemistry*; D013055:Spectrophotometry, Infrared