Toxicity and health-related quality-of-life assessment in prostate radiotherapy.
The use of radiation therapy in the radical treatment of prostate cancer can lead to potential acute and long-term toxicity and health-related quality-of-life (HRQoL) changes. Ongoing investigation into dose-escalation, dose-per-fraction escalation, new radiation treatment technology/paradigms, and novel systemic therapy may have either positive and/or negative effects on normal tissue toxicity/HRQoL. Herein, common toxicity scales and HRQoL instruments that attempt to describe the deleterious effects of prostate radiation therapy are reviewed.
Rodrigues
George
G
Department of Radiation Oncology, London Regional Cancer Program, London, Ontario, Canada.
Lock
Michael
M
D'Souza
David
D
D002986:Clinical Trials as Topic; D004307:Dose-Response Relationship, Radiation; D006801:Humans; D008297:Male; D011471:Prostatic Neoplasms / Q000532:radiotherapy*; D011788:Quality of Life; D011832:Radiation Injuries