Novel ligands stabilize stereo-selective conformations of the histamine H1 receptor to activate catecholamine synthesis.
Booth
R G
RG
Department of Medicinal Chemistry, PO Box 100485, College of Pharmacy, University of Florida, Gainesville, Florida 32610-0485, USA. Booth@cop.ufl.edu
Moniri
N H
NH
D000818:Animals; D016466:CHO Cells; D002395:Catecholamines / Q000096:biosynthesis*; D006224:Cricetinae; D003412:Cricetulus; D000242:Cyclic AMP / Q000378:metabolism; D006168:Guinea Pigs; D008024:Ligands; D008968:Molecular Conformation; D011969:Receptors, Histamine H1 / Q000737:chemistry / Q000378:metabolism; D015398:Signal Transduction / Q000502:physiology*; D010738:Type C Phospholipases / Q000378:metabolism; D014446:Tyrosine 3-Monooxygenase / Q000378:metabolism