title: Photodynamic therapy for the treatment of actinic cheilitis.
abstract: Although actinic cheilitis is a common disease, it should be treated carefully because it can undergo malignant transformation. We report a case of actinic cheilitis treated with photodynamic therapy (PDT) using 5-aminolevulinic acid (ALA), with satisfactory outcome in both clinical and pathological aspects. Actinic cheilitis is a pathologic condition affecting mainly the lower lip caused by long-term exposure of the lips to the UV radiation in sunlight. Analogous to actinic keratosis of the skin, actinic cheilitis is considered as a precancerous lesion and it may develop into squamous cell carcinoma. We report a case of actinic cheilitis treated with PDT using ALA, with satisfactory outcome in both clinical and pathological aspects.
authors.affiliation: Department of Dermatology, Aichi Medical University, Aichi, Japan.
authors.forename: Makiko
authors.initials: M
authors.lastname: Kodama
authors.forename: Daisuke
authors.initials: D
authors.lastname: Watanabe
authors.forename: Yoichi
authors.initials: Y
authors.lastname: Akita
authors.forename: Yasuhiko
authors.initials: Y
authors.lastname: Tamada
authors.forename: Yoshinari
authors.initials: Y
authors.lastname: Matsumoto
mesh_terms: D000368:Aged; D000622:Aminolevulinic Acid / Q000627:therapeutic use*; D002613:Cheilitis / Q000188:drug therapy* / Q000209:etiology; D005260:Female; D006801:Humans; D010778:Photochemotherapy; D013472:Sunlight / Q000009:adverse effects*