title: The value of computed tomography-guided percutaneous lung biopsy for diagnosis of invasive fungal infection in immunocompromised patients.
abstract: We assessed Calcofluor white staining, Aspergillus polymerase chain reaction, and a galactomannan enzyme immunoassay for diagnosis of fungal infection with use of computed tomography-guided percutaneous lung biopsy specimens obtained from 61 patients. The sensitivity and specificity of computerized tomography, Aspergillus polymerase chain reaction, and galactomannan enzyme immunoassay were 100% and 50%, 100% and 86%, and 88% and 94%, respectively.
authors.affiliation: Department of Hygiene, Microbiology and Social Medicine, Innsbruck Medical University, University Hospital Innsbruck, Innsbruck, Tirol, Austria. cornelia.lass-floerl@i-med.ac.at
authors.forename: Cornelia
authors.initials: C
authors.lastname: Lass-Flörl
authors.forename: Gudrun
authors.initials: G
authors.lastname: Resch
authors.forename: David
authors.initials: D
authors.lastname: Nachbaur
authors.forename: Astrid
authors.initials: A
authors.lastname: Mayr
authors.forename: Günther
authors.initials: G
authors.lastname: Gastl
authors.forename: Jutta
authors.initials: J
authors.lastname: Auberger
authors.forename: Ralf
authors.initials: R
authors.lastname: Bialek
authors.forename: Martin C
authors.initials: MC
authors.lastname: Freund
mesh_terms: D000328:Adult; D001228:Aspergillosis / Q000175:diagnosis*; D001230:Aspergillus / Q000235:genetics*; D001557:Benzenesulfonates; D001706:Biopsy / Q000379:methods*; D003287:Contrast Media; D005189:False Positive Reactions; D005260:Female; D005690:Galactose / Q000031:analogs & derivatives; D006801:Humans; D016867:Immunocompromised Host; D007124:Immunoenzyme Techniques / Q000379:methods; D008172:Lung Diseases, Fungal / Q000175:diagnosis*; D008297:Male; D008351:Mannans / Q000032:analysis*; D008875:Middle Aged; D016133:Polymerase Chain Reaction / Q000379:methods; D011446:Prospective Studies; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed / Q000379:methods