title: The lateral line microcosmos.
abstract: The lateral-line system is a simple sensory system comprising a number of discrete sense organs, the neuromasts, distributed over the body of fish and amphibians in species-specific patterns. Its development involves fundamental biological processes such as long-range cell migration, planar cell polarity, regeneration, and post-embryonic remodeling. These aspects have been extensively studied in amphibians by experimental embryologists, but it is only recently that the genetic bases of this development have been explored in zebrafish. This review discusses progress made over the past few years in this field.
authors.affiliation: Laboratory of Neurogenetics, Institut National de la Santé et de la Recherche Médicale (INSERM) U881, 34095 Montpellier, France. alain.ghysen@univ-montp2.fr
authors.forename: Alain
authors.initials: A
authors.lastname: Ghysen
authors.forename: Christine
authors.initials: C
authors.lastname: Dambly-Chaudière
mesh_terms: D000663:Amphibians; D000818:Animals; D019521:Body Patterning / Q000235:genetics; D002465:Cell Movement; D016764:Cell Polarity; D047108:Embryonic Development / Q000235:genetics*; D005399:Fishes; D018507:Gene Expression Regulation, Developmental; D006198:Hair Cells, Auditory / Q000196:embryology; D053403:Lateral Line System / Q000196:embryology* / Q000254:growth & development / Q000502:physiology; D008954:Models, Biological; D009457:Neuroglia / Q000502:physiology; D015027:Zebrafish / Q000196:embryology*