Simultaneous infection with more than one strain of Burkholderia pseudomallei is uncommon in human melioidosis.
A prospective study was performed to determine the rate at which patients with melioidosis are infected with more than one strain of Burkholderia pseudomallei. Genotyping of 2,058 bacterial colonies isolated from 215 samples taken from 133 patients demonstrated that mixed infection is uncommon (2/133 cases [1.5%; 95% confidence interval, 0.2 to 5.3%]).
Limmathurotsakul
Direk
D
Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
Wuthiekanun
Vanaporn
V
Chantratita
Narisara
N
Wongsuvan
Gumphol
G
Thanwisai
Aunchalee
A
Biaklang
Mayurachat
M
Tumapa
Sarinna
S
Lee
Sue
S
Day
Nicholas P J
NP
Peacock
Sharon J
SJ
D015373:Bacterial Typing Techniques; D016957:Burkholderia pseudomallei / Q000145:classification*; D016521:Electrophoresis, Gel, Pulsed-Field; D005838:Genotype; D006801:Humans; D008554:Melioidosis / Q000382:microbiology*; D011446:Prospective Studies; D017422:Sequence Analysis, DNA