title: Transient erythroblastopenia of childhood in siblings: case report and review of the literature.
abstract: Transient erythroblastopenia of childhood is characterized by anemia due to decreased production of red blood cell precursors. It is almost always self-resolving and requires clinical intervention only in severe cases. This article describes 2 cases in half-siblings diagnosed approximately 10 years apart. A review of the literature identifies 11 other sibling pairs. Our case suggests an autosomal dominant pattern of inheritance. To date, the gene involved in the development of transient erythroblastopenia of childhood has not been identified.
authors.affiliation: Department of Pediatrics, Orillia Soldier's Memorial Hospital, Orillia, Ontario, Canada.
authors.forename: Jordan
authors.initials: J
authors.lastname: Shaw
authors.forename: Robert
authors.initials: R
authors.lastname: Meeder
mesh_terms: D000741:Anemia, Aplastic / Q000175:diagnosis* / Q000235:genetics; D004900:Erythroblasts; D004920:Erythropoiesis / Q000235:genetics; D006801:Humans; D007223:Infant; D008297:Male; D035781:Siblings