[A clinical and pathological analysis on laryngeal contact granuloma among 18 cases].
OBJECTIVE
To summarize the clinicopathologic feature and diagnostic and therapeutic experience of laryngeal contact granuloma.


METHODS
A retrospective study was carried out among 18 cases with this disease through careful analysis on their clinical and pathological data.


RESULTS
All of 18 cases were male, aged 34 to 78 years,The most common symptoms were hoarseness. In general the granuloma located on the posterior of the larynx unilaterally. The histological appearances of the lesions were typical inflammatory granuloma. Little allotype cell were found in one histologic sample. Fifteen cases received surgical excision and the recurrence rate was 60% after operation. Recidivist received operation again,4 cases among these cases received antireflux therapy after operation but 3 cases recurrences again. Among those follow-up cases(3 cases), 1 case was self-cure and other 2 cases appeared no marked change during observation period.


CONCLUSIONS
Laryngeal contact granuloma predilected the middle-aged male. The localization and appearance of the granuloma is very characteristic. The correct diagnosis can be established by clinical examination alone, but the histological examination is necessary in order to avoid missed diagnosis. There is a high recurrence rate after operation and the effect of antireflux therapy need further research.
Ke
Zhaoyang
Z
Department of Otolaryngology, Second Clinical College of Jinan University, Shenzhen People's Hospital, Shenzhen 518020, China. kezhaoyang@tom.com
Luo
Shuqing
S
Liu
Ming
M
Zhang
Wei
W
Ma
Lingguo
L
D000328:Adult; D000368:Aged; D006102:Granuloma, Laryngeal / Q000473:pathology* / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D013517:Otorhinolaryngologic Surgical Procedures; D012189:Retrospective Studies