Microdetermination of Calcium by Aequorin Luminescence.
A bioluminescent protein, aequorin, isolated from the jellyfish Aequorea in dilute disodium ethylenediaminetetraacetate solution, emits light on addition specifically of Ca(++) or Sr(++), thus providing the basis for a simple, quantitative micromethod for the determination of these cations, especially in biological fluids.
Shimomura
O
O
Johnson
F H
FH
Saiga
Y
Y