title: Genetic diversity of paired middle-ear and pharyngeal nontypeable Haemophilus influenzae isolates from children with acute otitis media.
abstract: Pulsed-field gel electrophoresis was used to determine genetic diversities of multiple nontypeable Haemophilus influenzae isolates from throat and ear specimens of eight children with otitis media. From five children, all ear and throat isolates were identical. The bacterial populations in these specimens showed less diversity than populations in throat isolates of healthy children.
authors.affiliation: University of Michigan, Department of Pediatrics and Communicable Diseases, L2224 Women's Hospital, Ann Arbor, MI 48109-5244, USA.
authors.forename: Zachary J
authors.initials: ZJ
authors.lastname: Berrens
authors.forename: Carl F
authors.initials: CF
authors.lastname: Marrs
authors.forename: Melinda M
authors.initials: MM
authors.lastname: Pettigrew
authors.forename: Sara A
authors.initials: SA
authors.lastname: Sandstedt
authors.forename: Mayuri
authors.initials: M
authors.lastname: Patel
authors.forename: Janet R
authors.initials: JR
authors.lastname: Gilsdorf
mesh_terms: D000208:Acute Disease; D002648:Child; D004432:Ear, Middle / Q000382:microbiology*; D016521:Electrophoresis, Gel, Pulsed-Field; D014644:Genetic Variation; D006193:Haemophilus influenzae / Q000187:drug effects / Q000235:genetics*; D006801:Humans; D010033:Otitis Media / Q000209:etiology / Q000382:microbiology*; D010614:Pharynx / Q000382:microbiology*