title: The DAVID Gene Functional Classification Tool: a novel biological module-centric algorithm to functionally analyze large gene lists.
abstract: The DAVID Gene Functional Classification Tool http://david.abcc.ncifcrf.gov uses a novel agglomeration algorithm to condense a list of genes or associated biological terms into organized classes of related genes or biology, called biological modules. This organization is accomplished by mining the complex biological co-occurrences found in multiple sources of functional annotation. It is a powerful method to group functionally related genes and terms into a manageable number of biological modules for efficient interpretation of gene lists in a network context.
authors.affiliation: Laboratory of Immunopathogenesis and Bioinformatics, Clinical Services Program, SAIC-Frederick, Inc., National Cancer Institute at Frederick, Frederick, MD 21702, USA.
authors.forename: Da Wei
authors.initials: DW
authors.lastname: Huang
authors.forename: Brad T
authors.initials: BT
authors.lastname: Sherman
authors.forename: Qina
authors.initials: Q
authors.lastname: Tan
authors.forename: Jack R
authors.initials: JR
authors.lastname: Collins
authors.forename: W Gregory
authors.initials: WG
authors.lastname: Alvord
authors.forename: Jean
authors.initials: J
authors.lastname: Roayaei
authors.forename: Robert
authors.initials: R
authors.lastname: Stephens
authors.forename: Michael W
authors.initials: MW
authors.lastname: Baseler
authors.forename: H Clifford
authors.initials: HC
authors.lastname: Lane
authors.forename: Richard A
authors.initials: RA
authors.lastname: Lempicki
mesh_terms: D000465:Algorithms; D016000:Cluster Analysis; D019295:Computational Biology / Q000379:methods; D003627:Data Interpretation, Statistical; D030541:Databases, Genetic; D020869:Gene Expression Profiling; D005821:Genetic Techniques; D023281:Genomics; D006801:Humans; D008962:Models, Theoretical; D020411:Oligonucleotide Array Sequence Analysis; D010363:Pattern Recognition, Automated; D012984:Software