Diagnosis and management of nonconvulsive status epilepticus in children.
Nonconvulsive status epilepticus (NCSE) encompasses a wide range of diagnoses with variable outcomes and treatment recommendations. In children, NCSE can be observed in various conditions, including acute neurological injuries, specific childhood epilepsy syndromes and other neurological conditions, and can also be observed in individuals with learning difficulties. NCSE in children is thought to be under-recognized, and further studies examining the electrographic characteristics of very young children in NCSE would aid the prompt recognition of additional patients. Some subtypes of NCSE are probably more harmful than others, and long-term prospective studies are needed to evaluate the damaging potential of NCSE itself as opposed to that of the underlying circumstances in which it occurs. Specific data in childhood are clearly lacking, but extrapolation from adult studies indicates that aggressive treatment is most warranted in comatose patients. By contrast, a cautious approach seems to be indicated for absence status epilepticus, complex partial status epilepticus and electrical status epilepticus during sleep.
Korff
Christian M
CM
Children's Hospital, Geneva, Switzerland. christian.korff@hcuge.ch
Nordli
Douglas R
DR
D000818:Animals; D000927:Anticonvulsants / Q000627:therapeutic use; D002648:Child; D019468:Disease Management; D004569:Electroencephalography / Q000379:methods; D006801:Humans; D013226:Status Epilepticus / Q000175:diagnosis* / Q000503:physiopathology / Q000628:therapy*