title: SLAM-associated protein solves a mystery of autoimmunity.
abstract: SLAM-associated protein (SAP) is essential for viral protection, lifelong immune memory (vaccination), and lifelong autoantibody production. We discuss how SAP is a key player in the development of autoimmune disease.
authors.affiliation: Department of Rheumatology and Hematology, Nihon University Nerima Hikarigaoka Hospital, 2-11-1 Hikarigaoka, Nerima-ku, Tokyo 197-0072, Japan. sswd98@med.nihon-u.ac.jp
authors.forename: Shigemasa
authors.initials: S
authors.lastname: Sawada
authors.forename: Masami
authors.initials: M
authors.lastname: Takei
authors.forename: Tetsuyosi
authors.initials: T
authors.lastname: Ishiwata
authors.forename: Hidetaka
authors.initials: H
authors.lastname: Shiraiwa
authors.forename: Hirotake
authors.initials: H
authors.lastname: Inomata
authors.forename: Takamasa
authors.initials: T
authors.lastname: Nozaki
mesh_terms: D000818:Animals; D017209:Apoptosis; D001172:Arthritis, Rheumatoid / Q000276:immunology / Q000473:pathology; D015551:Autoimmunity / Q000276:immunology*; D003001:Cloning, Molecular; D005922:Glomerulonephritis, IGA / Q000235:genetics / Q000276:immunology; D006801:Humans; D047908:Intracellular Signaling Peptides and Proteins / Q000235:genetics / Q000276:immunology*; D008214:Lymphocytes / Q000378:metabolism; D008232:Lymphoproliferative Disorders / Q000235:genetics / Q000276:immunology