Multicentric reticulohistiocytosis: a proliferation of macrophages with tropism for skin and joints, part II.
In this second part of the review of multicentric reticulohistiocytosis, the authors discuss its association with other diseases, in particular, cancer, and laboratory and therapeutic aspects of this incapacitating and disfiguring disease. Histopathologic aspects are characteristic: dense mononuclear infiltrate with typical multinucleated cells that contain periodic acid-Schiff-positive and diastasis-resistant material, conferring a "ground glass" aspect when stained with hematoxylineosin.
Luz
Flávio Barbosa
FB
Sector of Dermatology, University Hospital HUCFF/UFRJ and School of Medicine, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil. luzbf@globo.com
Gaspar
Neide Kalil
NK
Gaspar
Antonio Pedro
AP
Carneiro
Sueli
S
Ramos-E-Silva
Marcia
M
D015703:Antigens, CD / Q000032:analysis; D001168:Arthritis / Q000000981:diagnostic imaging / Q000473:pathology*; D001327:Autoimmune Diseases / Q000150:complications; D001842:Bone and Bones / Q000000981:diagnostic imaging / Q000473:pathology*; D049109:Cell Proliferation; D006644:Histiocytes / Q000378:metabolism; D015616:Histiocytosis, Non-Langerhans-Cell / Q000209:etiology / Q000473:pathology / Q000628:therapy; D006801:Humans; D007596:Joints / Q000473:pathology*; D008854:Microscopy, Electron; D009369:Neoplasms / Q000150:complications; D011859:Radiography; D012867:Skin / Q000473:pathology*