title: RESPONSES OF SHEEP TO ZYGADENUS GRAMINEUS, "DEATH CAMAS".
abstract: An extract of Zygadenus gramineus, "death camas," from which most of the resins had been removed was given intravenously to sheep prepared for recording blood-pressure and respiratory movements. Following the intravenous injection of this extract there occurred a respiratory inhibition which in the case of the injection of larger amounts of the extract was followed by asphyxia-like rises of blood-pressure. The graphic record of this asphyxial condition was practically duplicated by closing the tracheal cannula for a short time following the recovery of the animal from the effects of the plant extract. Although, from a field standpoint, no satisfactory antidote has been found, it has been demonstrated that caffein sodio-benzoate possesses marked powers of stimulation for the respiratory center affected by the depressive substances found in Zygadenus gramineus.
authors.forename: A R
authors.initials: AR
authors.lastname: McLaughlin