title: Obesity not associated with medium-term prognosis among Japanese male survivors hospitalized for acute myocardial infarction.
abstract: BACKGROUND
  Obesity is an established risk factor for coronary heart disease. However, data on the relationship between obesity and prognosis following acute myocardial infarction (AMI) are still lacking in Japan.
  
  
  RESULTS
  In the present study, 1,458 AMI patients were enrolled in the AMI-Kyoto Multi-Center Risk Study between January 2000 and December 2003. Among survivors of hospitalized AMI, clinical characteristics and medium-term prognosis were retrospectively compared between 240 normal weight male patients [body mass index (BMI) 18.5-25.0 kg/m2, normal weight group], and 116 obese male patients (BMI > or = 25.0 kg/m2, obese group), who could be followed up after hospital discharge. The obese group were younger and had higher prevalence of smoking and hypercholesterolemia than the normal weight group. The two groups had similar angiographic findings and outcomes of primary percutaneous coronary intervention. During the follow-up period (mean 2.18 years for normal weight, 2.15 years for obese), overall mortality rate as well as event-free survival rate did not differ significantly between the two groups. Multivariate analysis showed the presence of previous myocardial infarction, diabetes mellitus, and age were predictors of medium-term mortality, but BMI was not.
  
  
  CONCLUSIONS
  These results suggest that obesity is not associated with increased medium-term mortality and cardiac morbidity in Japanese male survivors hospitalized for AMI.
authors.affiliation: Department of Cardiology, Kyoto First Red Cross Hospital, Honmachi 15 749, Higashiyama-ku, Kyoto 605-0981. sjun@msj.biglobe.ne.jp
authors.forename: Jun
authors.initials: J
authors.lastname: Shiraishi
authors.forename: Yoshio
authors.initials: Y
authors.lastname: Kohno
authors.forename: Takahisa
authors.initials: T
authors.lastname: Sawada
authors.forename: Masayasu
authors.initials: M
authors.lastname: Arihara
authors.forename: Masayuki
authors.initials: M
authors.lastname: Hyogo
authors.forename: Takakazu
authors.initials: T
authors.lastname: Yagi
authors.forename: Takatomo
authors.initials: T
authors.lastname: Shima
authors.forename: Takashi
authors.initials: T
authors.lastname: Okada
authors.forename: Takeshi
authors.initials: T
authors.lastname: Nakamura
authors.forename: Satoaki
authors.initials: S
authors.lastname: Matoba
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Yamada
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Tatsumi
authors.forename: Makoto
authors.initials: M
authors.lastname: Kitamura
authors.forename: Keizo
authors.initials: K
authors.lastname: Furukawa
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Matsubara
mesh_terms: D000368:Aged; D015906:Angioplasty, Balloon, Coronary; D015992:Body Mass Index; D006801:Humans; D007564:Japan / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000401:mortality* / Q000503:physiopathology / Q000628:therapy; D009765:Obesity; D011379:Prognosis; D012307:Risk Factors; D012907:Smoking / Q000453:epidemiology; D015996:Survival Rate; D016896:Treatment Outcome