Transient thrombocytopenia with large platelets in Kawasaki disease.
Kawasaki disease (KD) is a multisystem disorder of unknown origin and usually associated with thrombocytosis. The authors describe a case of KD exhibiting thrombocytopenia with markedly large platelets. Among the 173 KD cases, 3 cases exhibited thrombocytopenia. One of these showed cardiac involvement with giant aneurysm of the coronary artery (33%), while only 1 of the remaining 170 cases exhibited cardiac involvement without thrombocytopenia (0.6%). The authors believe that it is important for clinicians to be aware that thrombocytopenia may occur during the course of KD and that this may be a more active condition when compared with thrombocytosis.
Asano
Takeshi
T
Department of Pediatrics, Nippon Medical School, Chiba Hokusoh Hospital, Chiba-Pref, Japan. VFF13540@nifty.ne.jp
Sudoh
Mariko
M
Watanabe
Makoto
M
Fujino
Osamu
O
D001792:Blood Platelets / Q000276:immunology; D005260:Female; D006801:Humans; D007116:Immunization, Passive; D007223:Infant; D009080:Mucocutaneous Lymph Node Syndrome / Q000097:blood* / Q000276:immunology / Q000628:therapy; D013921:Thrombocytopenia / Q000276:immunology / Q000628:therapy; D013922:Thrombocytosis