Controversies in nephrology: renal albumin handling, facts, and artifacts!
In this article, we discuss and contradict a recent publication by Russo et al., which suggests that the filtration of large amounts of albumin followed by transtubular transport of intact albumin is a physiological phenomenon.
Christensen
E I
EI
Department of Cell Biology, Institute of Anatomy, University of Aarhus, Aarhus, Denmark. eic@ana.au.dk
Birn
H
H
Rippe
B
B
Maunsbach
A B
AB
D000418:Albumins / Q000378:metabolism* / Q000648:ultrastructure; D000818:Animals; D016477:Artifacts; D001345:Autoradiography; D001692:Biological Transport; D004705:Endocytosis; D005919:Glomerular Filtration Rate; D007457:Iodine Radioisotopes / Q000378:metabolism; D007668:Kidney / Q000737:chemistry* / Q000502:physiology*; D007687:Kidney Tubules, Proximal / Q000502:physiology / Q000648:ultrastructure; D051381:Rats; D017207:Rats, Sprague-Dawley