Multicentric Castleman's disease: a case report.
Castleman's disease is a clinicopathological entity associated with lymphoproliferation. We report a case of a 71 year old gentleman who was initially clinically suspected to have lymphoma (owing to clinical features at presentation), but was later histologically confirmed to have Castleman's disease. This case report underlines the importance of definitive histological diagnosis in patients with lympadenopathic presentation associated with systemic symptoms and the distinctiveness of multicentric Castleman's disease from malignant lymphoma. In this report we also attempt to provide new insight (through the review of medical literature) into the clinical features, pathogenesis, diagnosis and treatment of this rare and relatively benign disorder.
Menezes
Brian F
BF
Department of Medicine, University Hospital Aintree, Liverpool L9 7AL, UK. franmenezes77@yahoo.co.uk.
Morgan
Rosemary
R
Azad
Mohammed
M