title: Serum uric acid is significantly related to the components of the metabolic syndrome in Japanese workingmen.
abstract: The aim of this study was to examine whether serum uric acid (SUA) concentration was related to the metabolic syndrome (MS). A total of 981 Japanese workingmen were studied. MS was diagnosed based on the modified criteria of the International Diabetes Federation. MS was present in 8.0% of the target participants. Logistic regression analysis using a cutoff value of the SUA of 7.0 mg/dL showed that some components of MS and the logarithmic value of the serum C-reactive protein were associated with a significant odds ratio for predicting elevated SUA. The odds ratios and 95% confidence intervals (CIs) of a high logarithmic value of the serum C-reactive protein, large waist girth, elevated blood pressure, and dyslipidemia for elevated SUA were 1.76 (CI, 1.21-2.55), 1.72 (CI, 1.21-2.45), 1.42 (CI, 1.01-2.00), and 1.87 (CI, 1.30-2.69), respectively. Most of the components of MS were significant determinants of SUA.
authors.affiliation: Department of Hygiene and Public Health, Nippon Medical School, Tokyo, Japan. kawada@nms.ac.jp
authors.forename: Tomoyuki
authors.initials: T
authors.lastname: Kawada
authors.forename: Toshiaki
authors.initials: T
authors.lastname: Otsuka
authors.forename: Masao
authors.initials: M
authors.lastname: Katsumata
authors.forename: Hiroko
authors.initials: H
authors.lastname: Suzuki
mesh_terms: D000328:Adult; D015415:Biomarkers / Q000097:blood; D001786:Blood Glucose; D002097:C-Reactive Protein / Q000378:metabolism; D003430:Cross-Sectional Studies; D050171:Dyslipidemias / Q000097:blood*; D004651:Employment; D006801:Humans; D006973:Hypertension / Q000097:blood*; D007564:Japan; D016015:Logistic Models; D008297:Male; D024821:Metabolic Syndrome / Q000097:blood*; D008875:Middle Aged; D009765:Obesity / Q000097:blood* / Q000453:epidemiology; D012307:Risk Factors; D011795:Surveys and Questionnaires; D014527:Uric Acid / Q000097:blood*