title: Anti-Yo-associated paraneoplastic cerebellar degeneration in a man with adenocarcinoma of the gastroesophageal junction.
abstract: Anti-Yo-associated paraneoplastic cerebellar degeneration is a cancer-related syndrome affecting the nervous system. This syndrome occurs almost exclusively in middle-aged women with gynecological cancers and it is rarely found in patients with other types of cancer or in males. In this report we describe a male patient adenocarcinoma of the gastroesophageal junction and PCD with anti-Yo antibodies. To our knowledge, this is only the third report of PCD with positive anti-Yo antibodies in an esophageal tumor and the first report in a tumor of the gastroesophageal junction.
authors.affiliation: Department of Surgery, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
authors.forename: J D
authors.initials: JD
authors.lastname: Debes
authors.forename: S M
authors.initials: SM
authors.lastname: Lagarde
authors.forename: E
authors.initials: E
authors.lastname: Hulsenboom
authors.forename: P A E
authors.initials: PA
authors.lastname: Sillevis Smitt
authors.forename: F J W
authors.initials: FJ
authors.lastname: ten Kate
authors.forename: G A
authors.initials: GA
authors.lastname: Sulter
authors.forename: J J B
authors.initials: JJ
authors.lastname: van Lanschot
mesh_terms: D000230:Adenocarcinoma / Q000276:immunology* / Q000473:pathology; D004938:Esophageal Neoplasms / Q000276:immunology* / Q000473:pathology; D004943:Esophagogastric Junction; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008875:Middle Aged; D009419:Nerve Tissue Proteins / Q000276:immunology*; D020362:Paraneoplastic Cerebellar Degeneration / Q000276:immunology* / Q000473:pathology