[Acute cholestatic hepatitis caused by simvastatine in a 67-year-old patient].
The following work presents the case of undesired during side effect (toxic hepatocellular damage ) by Simvastatine (Cardin). The main syptoms were jaundice and pruritus. Conclusions draw the attention to the role of history taking in the diagnosis of the described disease, as well as the importance of regular patient checkups whoin those use statines.
Lata
Stanisław
S
II Odział Chorób Wewnetrznych i Ostrych Zatruć Szpital Wojewódzki im. Sw. Lukasza w Tamowie.
Chudy
Barbara
B
D000208:Acute Disease; D000368:Aged; D056486:Chemical and Drug Induced Liver Injury / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology*; D002780:Cholestasis, Intrahepatic / Q000139:chemically induced* / Q000175:diagnosis* / Q000188:drug therapy; D006801:Humans; D006932:Hyperbilirubinemia / Q000097:blood / Q000139:chemically induced; D041781:Jaundice, Obstructive / Q000139:chemically induced* / Q000175:diagnosis* / Q000188:drug therapy; D008297:Male; D011241:Prednisone / Q000627:therapeutic use; D011537:Pruritus / Q000139:chemically induced / Q000188:drug therapy; D019821:Simvastatin / Q000009:adverse effects* / Q000627:therapeutic use; D016896:Treatment Outcome