title: Swallowing disorders in the first year after radiation and chemoradiation.
abstract: BACKGROUND
  Radiation alone or concurrent chemoradiation can result in severe swallowing disorders. This manuscript defines the swallowing disorders occurring at pretreatment and 3 and 12 months after completion of radiation or chemoradiation.
  
  
  METHODS
  Forty-eight patients (10 women and 38 men) participated in this study involving videofluorographic evaluation of oropharyngeal swallow at the 3 time points.
  
  
  RESULTS
  At baseline, patients had some swallow disorders, probably related to presence of their tumor. At 3 months posttreatment, frequency of reduced tongue base retraction, slow or delayed laryngeal vestibule closure, and reduced laryngeal elevation increased from baseline. Some disorders continued at 12 months posttreatment. Functional swallow decreased over time in patients treated with chemoradiation, but not those treated with radiation alone.
  
  
  CONCLUSIONS
  Chemoradiation results in fewer functional swallowers than radiation alone at 12 months posttreatment completion.
authors.affiliation: Department of Communication Sciences and Disorders, Northwestern University, Evanston, Illinois, USA. j-logemann@northwestern.edu
authors.forename: Jeri A
authors.initials: JA
authors.lastname: Logemann
authors.forename: Barbara Roa
authors.initials: BR
authors.lastname: Pauloski
authors.forename: Alfred W
authors.initials: AW
authors.lastname: Rademaker
authors.forename: Cathy L
authors.initials: CL
authors.lastname: Lazarus
authors.forename: Joy
authors.initials: J
authors.lastname: Gaziano
authors.forename: Linda
authors.initials: L
authors.lastname: Stachowiak
authors.forename: Lisa
authors.initials: L
authors.lastname: Newman
authors.forename: Ellen
authors.initials: E
authors.lastname: MacCracken
authors.forename: Daphne
authors.initials: D
authors.lastname: Santa
authors.forename: Bharat
authors.initials: B
authors.lastname: Mittal
mesh_terms: D000328:Adult; D000368:Aged; D003131:Combined Modality Therapy; D003680:Deglutition Disorders / Q000453:epidemiology*; D005260:Female; D005471:Fluoroscopy; D006258:Head and Neck Neoplasms / Q000188:drug therapy / Q000532:radiotherapy; D006801:Humans; D007822:Laryngeal Neoplasms / Q000188:drug therapy / Q000532:radiotherapy; D008297:Male; D008875:Middle Aged; D009959:Oropharyngeal Neoplasms / Q000188:drug therapy* / Q000532:radiotherapy*; D011446:Prospective Studies; D011878:Radiotherapy / Q000009:adverse effects; D011879:Radiotherapy Dosage