title: Retention of potential to differentiate in long-term cultures of tooth germs.
abstract: When tooth germs derived from 14-day mouse embryos were cultured on gelatin sponges in vitro for 37 days, they lost their characteristic morphology, appearing as a layer of undifferentiated epithelium on the sponge surface, with the mesenchymal cells scattered throughout the interstices. These cultures were then transplanted subcutaneously into isologous, newborn recipients and, over a period of 56 days, developed into incisor teeth that were almost perfect in shape and structure.
authors.forename: J H
authors.initials: JH
authors.lastname: Main