Phosphine-catalyzed construction of sulfur heterocycles.
A simple and efficient method for constructing sulfur heterocycles was developed using a phosphine-catalyzed tandem umpolung addition and intramolecular cyclization of bifunctional sulfur pronucleophiles on arylpropiolates. The reaction offers a promising route to synthetically useful as well as biologically active heterocycles under neutral conditions.
Gabillet
Sandra
S
CEA, iBiTecS, Service de Chimie Bioorganique et de Marquage, Gif sur Yvette F-91191, France.
Lecerclé
Delphine
D
Loreau
Olivier
O
Carboni
Michael
M
Dézard
Sophie
S
Gomis
Jean-Marie
JM
Taran
Frédéric
F
D002384:Catalysis; D003500:Cyclization; D006571:Heterocyclic Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D010720:Phosphines / Q000737:chemistry*; D012235:Rhodamines / Q000737:chemistry; D013457:Sulfur Compounds / Q000138:chemical synthesis* / Q000737:chemistry