PCR real time assays for the early detection of BKV-DNA in immunocompromised patients.
Testing for viral BKV-DNA in urine is a non-invasive early detection and monitoring tool in the diagnostic of BKV-related pathologies: quantitative analysis by Real-Time PCR can provide useful information in addition to cytologic analysis, although our study suggests that high BKV viruria is not necessarily associated with kidney or bladder damage.
Marinelli
Katia
K
Istitito di Microbiologia e Scienze Biomediche, Università Politecnica delle Marche, Ancona, Italy.
Bagnarelli
Patrizia
P
Gaffi
Gianni
G
Trappolini
Silvia
S
Leoni
Pietro
P
Paggi
Alessandra Mataloni
AM
Della Vittoria
Agnese
A
Scalise
Giorgio
G
Varaldo
Pietro Emanuele
PE
Menzo
Stefano
S
D000293:Adolescent; D000328:Adult; D000368:Aged; D001739:BK Virus / Q000302:isolation & purification* / Q000502:physiology; D002648:Child; D002675:Child, Preschool; D004279:DNA, Viral / Q000652:urine*; D042241:Early Diagnosis; D005260:Female; D006801:Humans; D016867:Immunocompromised Host; D007223:Infant; D007674:Kidney Diseases / Q000175:diagnosis* / Q000821:virology; D016030:Kidney Transplantation; D008297:Male; D008875:Middle Aged; D016133:Polymerase Chain Reaction; D027601:Polyomavirus Infections / Q000175:diagnosis*; D012680:Sensitivity and Specificity; D014412:Tumor Virus Infections / Q000175:diagnosis* / Q000821:virology; D014775:Virus Activation