Chiral memory: induction, amplification, and switching in porphyrin assemblies.
The interaction between the tetra-anionic porphyrin H2TPPS and its copper derivative, CuTPPS, with the tetra-cationic porphyrin H2T4 and its copper derivative, CuT4, leads, in aqueous solution, to the formation of remarkably stable and kinetically inert heteroaggregates. The aggregation process is under hierarchic control and, in the presence of a suitable chiral mold, leads to the formation of chiral porphyrin heteroassemblies as stable and inert as the achiral ones. Because of these properties, the chirality of the porphyrin "imprinted" heteroaggregates not only survives the disruption of the template, but also to its complete removal from the solution. Notably, the template-free chiral porphyrin system is an excellent mold for its own self-replication. The relevant characteristics of these chiral heteroaggregates together with the knowledge of the forces that guide the aggregation processes permitted us to design a new but similar system. This system not only is able to store chiral information, but also is capable to release and restore it reversibly, in a cyclic manner. This has been achieved by modulating the charges carried by one of the two coupled porphyrins through protonation under various pH conditions. The role of the central metal ion and the template-free chiral structure of the CuT4-H2TPPS heteroaggregate, determined through EDXD analysis, are also presented.
Rosaria
Lauceri
L
CNR, Istituto di Biostrutture e Bioimmagini-Sezione di Catania, 95125 Catania, Italy. rlauceri@unict.it
D'urso
Alessandro
A
Mammana
Angela
A
Purrello
Roberto
R
D002942:Circular Dichroism; D046911:Macromolecular Substances / Q000737:chemistry; D008665:Metalloporphyrins / Q000737:chemistry; D008958:Models, Molecular; D008968:Molecular Conformation; D011166:Porphyrins / Q000737:chemistry*; D013237:Stereoisomerism