title: [Role of video-capsule endoscopy in Crohn's disease].
abstract: The technical and scientific improvements of the miniature electronic equipment made possible the occurrence of video-capsule endoscopy (VCE), which is a device having an enormous noninvasive investigation potential of the small intestine. One of the most attractive indications of VCE is the suspicion of Crohn's disease that has not been confirmed using standard imaging techniques.
  
  
  OBJECTIVE
  To assess the value of VCE in the diagnostic work-up of patients in whom there is clinical suspicion of small bowel Crohn's disease that cannot be confirmed using conventional techniques (upper and lower endoscopy, small bowel follow-through).
  
  
  METHODS
  A total of 21 patients (10 men, 11 women, mean age 36 +/- 7 years) with clinical and biochemical suspicion of Crohn's disease were included in the study. All the patients were evaluate before by the small bowel follow through, upper gastrointestinal endoscopy and colonoscopy.
  
  
  RESULTS
  In 15 patients (68%), lesions supporting the Crohn's disease diagnosis were detected by VCE. Complete visualization of the small bowel was achieved in all patients except for one where the capsule stopped upstream of a stenosis located at the terminal ileum level. The most frequent lesions included mucous erosions, aphthae, lineal or serpiginous mucous lesions, ulcers and fissures.
  
  
  CONCLUSIONS
  VCE is an effective modality for diagnosis patients with suspected Crohn's disease undetected by conventional diagnostic techniques.
authors.affiliation: Université de Mediciné et de Pharmacie Gr. T. Popa, Iaşi, Institut de Gastroentérologie et Hépatologie de Iaşi.
authors.forename: Anca
authors.initials: A
authors.lastname: Trifan
authors.forename: C
authors.initials: C
authors.lastname: Stanciu
authors.forename: Elena
authors.initials: E
authors.lastname: Toader
authors.forename: Maria
authors.initials: M
authors.lastname: Creţu
mesh_terms: D000293:Adolescent; D000328:Adult; D053704:Capsule Endoscopy; D003424:Crohn Disease / Q000175:diagnosis* / Q000473:pathology; D005260:Female; D006801:Humans; D007079:Ileitis / Q000175:diagnosis; D007413:Intestinal Mucosa / Q000473:pathology; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012680:Sensitivity and Specificity