The renal phospholipid composition of choline-deficient rats.
The base composition of the phospholipids involved in the N-methylation pathway for the biosynthesis of phosphatidyl choline was determined in normal and severely hemorrhagic rat kidneys. There was a decrease in the proportion of phosphatidyl choline and phosphatidyl ethanolamine in the renal total lipids. The significant decrease of phosphatidyl ethanolamine in the kidney phospholipids appears to implicate this phospholipid to a greater extent than phosphatidyl choline in the etiology of the hemorrhagic syndrome.
Fewster
M E
ME
Department of Biological Chemistry, UCLA School of Medicine, Los Angeles, California.
Hall
M O
MO