Candida albicans biofilms produce more secreted aspartyl protease than the planktonic cells.
By using a simple, low-cost system of polystyrene centrifuge tubes we compared the secreted aspartyl proteases (Saps) secretion during the biphasic growth modes of Candida albicans using twenty-one clinical isolates. Our results indicate that biofilms of C. albicans consistently secrete more Saps than their planktonic counterparts.
Mendes
Aline
A
Laboratory of Stomatology, Faculty of Dentistry, Pontifical Catholic University of Paraná, Brazil.
Mores
Alinne Ulbrich
AU
Carvalho
Alessandra Paula
AP
Rosa
Rosimeire Takaki
RT
Samaranayake
Lakshman Perera
LP
Rosa
Edvaldo Antonio Ribeiro
EA
D016282:Aspartic Acid Endopeptidases / Q000378:metabolism*; D018441:Biofilms; D018533:Biomass; D002176:Candida albicans / Q000201:enzymology* / Q000254:growth & development / Q000502:physiology; D008928:Mitochondria / Q000201:enzymology; D013778:Tetrazolium Salts