New advances in nanomedicine: diagnosis and preventive medicine.
This article describes the use of nanobiologic techniques in diagnosis and preventive medicine. It discusses the engineering of fluorescent and bioluminescent proteins to visualize biologic functions; single-molecule measurements of protein structure and function; two-photon microscopy for molecular imaging of the structure and function in living cells and tissues; and imaging ligand-induced protein conformations and interactions by fluorescence in single living cells.
Wei
Chiming
C
Department of Surgery, Johns Hopkins University School of Medicine, 600 N. Wolfe Street/Harvey 606, Baltimore, MD 21205, USA. chimingwei@gmail.com
Nagai
Takeharu
T
Wei
Wenchi
W
Nemoto
Tomomi
T
Awais
Muhammad
M
Niwa
Osamu
O
Kurita
Ryoji
R
Baba
Yashinobu
Y
D000818:Animals; D019937:Diagnostic Techniques and Procedures / Q000295:instrumentation*; D004867:Equipment Design; D006801:Humans; D050997:Nanomedicine / Q000379:methods / Q000639:trends*; D049329:Nanostructures; D011315:Preventive Medicine / Q000295:instrumentation*