title: Small cell carcinoma of the cervix: a case report.
abstract: Small cell carcinoma of the uterine cervix accounts for 1-3% of all cervix cancers. It is an aggressive disease with a poor prognosis. To date, no effective treatment protocol has been determined. Surgery, radiotherapy, and chemotherapy have been used either alone or in combination. Recent data suggests that survival in patients with early staged small cell carcinoma of the cervix is better with surgery combined with chemo-radiotherapy. Here, we presented two patients with stage IB1 small cell carcinoma of the uterine cervix. For both patients, definitive surgery was performed with pelvic and para-aortic lymphadenectomy. Subsequently, they were treated with pelvic external radiotherapy and high-dose-rate intracavitary brachytherapy with concurrent cisplatin based chemotherapy. They were alive with no evidence of disease at 91 and 65 months, respectively.
authors.affiliation: Department of Radiation Oncology, Akdeniz University, School of Medicine, 07070, Antalya, Turkey. aylinfk07@yahoo.com
authors.forename: Aylin Fidan
authors.initials: AF
authors.lastname: Korcum
authors.forename: Gamze
authors.initials: G
authors.lastname: Aksu
authors.forename: Hakan
authors.initials: H
authors.lastname: Bozcuk
authors.forename: Elif
authors.initials: E
authors.lastname: Pestereli
authors.forename: Tayup
authors.initials: T
authors.lastname: Simsek
mesh_terms: D000328:Adult; D000972:Antineoplastic Agents, Phytogenic / Q000627:therapeutic use; D001918:Brachytherapy; D018288:Carcinoma, Small Cell / Q000473:pathology / Q000628:therapy*; D002584:Cervix Uteri / Q000473:pathology; D002945:Cisplatin / Q000008:administration & dosage; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D011247:Pregnancy; D002583:Uterine Cervical Neoplasms / Q000473:pathology / Q000628:therapy*