title: Iridoids from Pentas lanceolata.
abstract: From the aerial parts of Pentas lanceolata, belonging to the family Rubiaceae, a series of iridoid glucosides was isolated by preparative HPLC. Seven iridoid glucosides were identified. Besides asperuloside and asperulosidic acid, characteristic iridoids for Rubiaceae, five new iridoids were isolated, namely, tudoside (1), 13R-epi-gaertneroside (2), 13R-epi-epoxygaertneroside (3), and a mixture of E-uenfoside (4) and Z-uenfoside (5). Further, it was shown that the compound reported as citrifolinin B (6) is in fact the same as tudoside and should be revised. Also, the configuration of the previously reported iridoids gaertneroside and epoxygaertneroside has been elucidated.
authors.affiliation: Analytical Biotechnology, Department of Biotechnology, Delft University of Technology, Julianalaan, Delft, The Netherlands. j.schripsema@tudelft.nl
authors.forename: Jan
authors.initials: J
authors.lastname: Schripsema
authors.forename: Geisa Paulino
authors.initials: GP
authors.lastname: Caprini
authors.forename: Rob
authors.initials: R
authors.lastname: van der Heijden
authors.forename: Raoul
authors.initials: R
authors.lastname: Bino
authors.forename: Ric
authors.initials: R
authors.lastname: de Vos
authors.forename: Denise
authors.initials: D
authors.lastname: Dagnino
mesh_terms: D001938:Brazil; D039823:Iridoids / Q000737:chemistry / Q000302:isolation & purification*; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D019666:Rubiaceae / Q000737:chemistry*