title: Phenotypic Alterations in Adrenal Tumor Cultures.
abstract: Adrenal tumor cells in culture gradually develop a requirement for glutamine and serum albumin in order to produce steroids in response to adrenocorticotropic hormone. Glutamine acts simply as a precursor for a protein or proteins whose synthesis is required for the response to the hormone. Albumin apparently binds steroid hormone products that otherwise would inhibit further biosynthesis of steroids.
authors.forename: G H
authors.initials: GH
authors.lastname: Sato
authors.forename: T
authors.initials: T
authors.lastname: Rossman
authors.forename: L
authors.initials: L
authors.lastname: Edelstein
authors.forename: S
authors.initials: S
authors.lastname: Holmes
authors.forename: V
authors.initials: V
authors.lastname: Buonassisi