Two therapeutic challenges: periocular and genital vitiligo in children successfully treated with pimecrolimus cream.
Vitiligo is characterized by the selective destruction of melanocytes resulting in patches of skin depigmentation. Vitiligo is a therapeutic challenge. Eyebrows, eyelids and genital vitiligo are a therapeutic dilemma, especially in children. The possible side effects of topical corticosteroids and the difficulties for choosing any other adequate treatment option are a major concern. We present two children, one with vitiligo of the eyelids and the other with genital vitiligo, both treated with pimecrolimus 1% cream with almost full repigmentation of the lesions, showing pimecrolimus could be an adequate option for the treatment of vitiligo for these special vitiligo areas in children.
Souza Leite
Rubens Marcelo
RM
Universidade Católica de Brasília and Instituto Saint Louis de Brasília, Brazilia, Brazil. rmsl@terra.com.br
Craveiro Leite
Adriana Aragão
AA
D000287:Administration, Topical; D002648:Child; D005143:Eyelids / Q000473:pathology; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D008297:Male; D010413:Penis / Q000473:pathology; D012074:Remission Induction; D012867:Skin / Q000473:pathology; D016559:Tacrolimus / Q000031:analogs & derivatives* / Q000627:therapeutic use; D014820:Vitiligo / Q000188:drug therapy* / Q000473:pathology