title: Serological investigation of ovine theileriosis by ELISA in Gannan Tibet Region of Gansu Province in China.
abstract: The Gannan Tibet Autonomous Region is the biggest and most important stock-raising region of Gansu Province, People's Republic of China. Many sheep and goats from this region suffer from Theileria challenge each year, resulting in inestimable economical losses. A first large-scale serological investigation by enzyme-linked immunosorbent assay of ovine theileriosis in this region was performed by testing a total of 1,165 sera samples collected from seven districts of three counties. The results showed that seroprevalence of reactive antibodies varied from 27.8 to 83.3%, whereby the average was 70.1% in the disease-endemic areas. Another 44 sera samples collected every month from July 2004 to June 2005 from a stable flock of sheep in Biandu Town of Lintan County were analysed to evaluate the seasonal kinetics of anti-Theileria antibodies. The results indicated that anti-Theileria antibody seroprevalence rose from March, reaching a peak value of 68.2% in May, declining in October and reaching the lowest value of 36.4% in January. The data indicate that seroprevalence of anti-Theileria antibodies correlate to the known activities of its transmitting vector and also imply that chemical therapy of animals should be performed during May to June in these Theileriosis-epidemic regions.
authors.affiliation: Animal Husbandry and Veterinary Medicine Institute of Gannan Tibet Autonomous Region, Hezuo, Gansu, PR China.
authors.forename: Shuzhen
authors.initials: S
authors.lastname: Guo
authors.forename: Yongjuan
authors.initials: Y
authors.lastname: Mu
authors.forename: Zhijie
authors.initials: Z
authors.lastname: Liu
authors.forename: Denlu
authors.initials: D
authors.lastname: Ma
authors.forename: Shumen
authors.initials: S
authors.lastname: Yang
authors.forename: Guihua
authors.initials: G
authors.lastname: Ge
authors.forename: Baiqian
authors.initials: B
authors.lastname: Fang
authors.forename: Danji
authors.initials: D
authors.lastname: Ga
authors.forename: Miling
authors.initials: M
authors.lastname: Ma
authors.forename: Jianxun
authors.initials: J
authors.lastname: Luo
authors.forename: Hong
authors.initials: H
authors.lastname: Yin
authors.forename: Ulrike
authors.initials: U
authors.lastname: Seitzer
authors.forename: Jabbar S
authors.initials: JS
authors.lastname: Ahmed
mesh_terms: D000818:Animals; D000913:Antibodies, Protozoan / Q000097:blood*; D002681:China / Q000453:epidemiology; D004797:Enzyme-Linked Immunosorbent Assay; D012621:Seasons; D016036:Seroepidemiologic Studies; D012756:Sheep; D016794:Theileria / Q000276:immunology*; D013801:Theileriasis / Q000097:blood* / Q000453:epidemiology*