title: Successful preoperative treatment of pediatric bladder inflammatory myofibroblastic tumor with anti-inflammatory therapy.
abstract: Inflammatory myofibroblastic tumors are rare, locally invasive tumors that can involve the genitourinary tract. Therapy has consisted primarily of surgery, and anecdotal experience using both chemotherapy and radiotherapy, which have yielded unimpressive results. We report the first case of a bladder inflammatory myofibroblastic tumor that responded to an anti-inflammatory regimen (prednisone and Cox-2 inhibitor) before surgical extirpation.
authors.affiliation: Division of Pediatric Urology and University of Connecticut Health Center, Farmington, Connecticut, USA.
authors.forename: Alisa
authors.initials: A
authors.lastname: Berger
authors.forename: Christina
authors.initials: C
authors.lastname: Kim
authors.forename: Nathan
authors.initials: N
authors.lastname: Hagstrom
authors.forename: Fernando
authors.initials: F
authors.lastname: Ferrer
mesh_terms: D018931:Antineoplastic Agents, Hormonal / Q000627:therapeutic use*; D002675:Child, Preschool; D052246:Cyclooxygenase 2 Inhibitors / Q000627:therapeutic use*; D006801:Humans; D007249:Inflammation / Q000150:complications; D008297:Male; D009379:Neoplasms, Muscle Tissue / Q000150:complications / Q000188:drug therapy*; D011241:Prednisone / Q000627:therapeutic use*; D011300:Preoperative Care; D012074:Remission Induction; D001749:Urinary Bladder Neoplasms / Q000150:complications / Q000188:drug therapy*