title: Two-stage revision of infected uncemented lower extremity tumor endoprostheses.
abstract: We reviewed our experience with 2-stage revision of uncemented Kotz Modular Femoral and Tibial Replacement System prostheses from 1989 to 2004. A total of 180 lower extremity tumor prostheses were inserted, 15 of which underwent removal of the prosthesis for infection. Eleven patients underwent subsequent second-stage revision, and 4 underwent amputation. Of the 11 patients who underwent revision, 8 continue to be free of infection an average of 33 months postoperatively. Of these 8 patients, 6 were revised without removal of the diaphyseal anchorage piece, which were all well ingrown. Most successful revisions were in the group that developed infection within 6 months of their original procedure. Two-stage revision of uncemented tumor endoprostheses with retention of a well-ingrown stem can be associated with successful eradication of infection.
authors.affiliation: Orthopaedic Oncology Unit, Middlemore Hospital, Auckland, New Zealand.
authors.forename: Michael N
authors.initials: MN
authors.lastname: Flint
authors.forename: Anthony M
authors.initials: AM
authors.lastname: Griffin
authors.forename: Robert S
authors.initials: RS
authors.lastname: Bell
authors.forename: Jay S
authors.initials: JS
authors.lastname: Wunder
authors.forename: Peter C
authors.initials: PC
authors.lastname: Ferguson
mesh_terms: D000293:Adolescent; D000328:Adult; D000671:Amputation, Surgical; D001178:Arthroplasty; D001186:Artificial Limbs; D001859:Bone Neoplasms / Q000601:surgery*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011475:Prosthesis Failure; D016459:Prosthesis-Related Infections / Q000601:surgery*; D012086:Reoperation / Q000379:methods; D012509:Sarcoma / Q000601:surgery*; D013997:Time Factors