title: [Cisplatin ototoxicity: series of cases].
abstract: OBJECTIVE
  To evaluate the clinic and audiometric evolution of individuals who underwent chemotherapy with cisplatin.
  
  
  METHODS
  Four volunteers, all women, between 38 and 69 years of age were descriptively evaluated. All did otorinolaryngoiatric exam and audiometric evaluation with tonal and speech audiometric and impedance tests before and after treatment with cisplatin. In addition, all were subjectively evaluated pre- and post-chemotherapy by a questionnaire.
  
  
  RESULTS
  One volunteer did not present auditory disorders. Three volunteers presented bilateral hearing loss, mild to moderate in 6 kHz and 8 kHz frequencies, after chemotherapy with cisplatin. All volunteers who developed hearing loss after treatment also presented tinnitus.
  
  
  CONCLUSIONS
  Since cisplatin is considered ototoxic, all individuals undergoing chemotherapy with this drug must be submitted to audiometric monitoring for early diagnosis of a hearing loss.
authors.affiliation: Hospital Universitário Oswaldo Cruz. luizmota10@hotmail.com
authors.forename: Luiz Alberto Alves
authors.initials: LA
authors.lastname: Mota
authors.forename: Marília Silvino Iglésias
authors.initials: MS
authors.lastname: Melo
authors.forename: Maria Heloísa Pedrosa
authors.initials: MH
authors.lastname: Santos
authors.forename: Kátia Maria Gomes
authors.initials: KM
authors.lastname: de Albuquerque
authors.forename: Cristiana de Lima
authors.initials: Cde L
authors.lastname: Tavares
mesh_terms: D000328:Adult; D000368:Aged; D000970:Antineoplastic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D001299:Audiometry; D002945:Cisplatin / Q000009:adverse effects* / Q000627:therapeutic use; D005260:Female; D006312:Hearing Loss, Bilateral / Q000139:chemically induced / Q000503:physiopathology; D006801:Humans; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000188:drug therapy*; D012016:Reference Values; D013997:Time Factors; D014012:Tinnitus / Q000139:chemically induced / Q000503:physiopathology; D014594:Uterine Neoplasms / Q000188:drug therapy*