Successful preoperative treatment of pediatric bladder inflammatory myofibroblastic tumor with anti-inflammatory therapy.
Inflammatory myofibroblastic tumors are rare, locally invasive tumors that can involve the genitourinary tract. Therapy has consisted primarily of surgery, and anecdotal experience using both chemotherapy and radiotherapy, which have yielded unimpressive results. We report the first case of a bladder inflammatory myofibroblastic tumor that responded to an anti-inflammatory regimen (prednisone and Cox-2 inhibitor) before surgical extirpation.
Berger
Alisa
A
Division of Pediatric Urology and University of Connecticut Health Center, Farmington, Connecticut, USA.
Kim
Christina
C
Hagstrom
Nathan
N
Ferrer
Fernando
F
D018931:Antineoplastic Agents, Hormonal / Q000627:therapeutic use*; D002675:Child, Preschool; D052246:Cyclooxygenase 2 Inhibitors / Q000627:therapeutic use*; D006801:Humans; D007249:Inflammation / Q000150:complications; D008297:Male; D009379:Neoplasms, Muscle Tissue / Q000150:complications / Q000188:drug therapy*; D011241:Prednisone / Q000627:therapeutic use*; D011300:Preoperative Care; D012074:Remission Induction; D001749:Urinary Bladder Neoplasms / Q000150:complications / Q000188:drug therapy*