Chemical constituents of the aerial parts of Kalidium foliatum.
Studies on the chemical constituents of the aerial parts of Kalidium foliatum have led to the isolation of three new and one known compounds. The structures of new constituents have been elucidated through spectral studies including 2D-NMR experiments (HMQC, HMBC, COSY, NOESY and J-resolved) and MS/MS fragmentation using Q-TOF mass spectrometer equipped with an ESI source as kalidiumoside C (=3beta-hydroxy-29-methylmalonoxy-olean-12-en-23,28-dioic acid-23-methyl-28-beta-D-glucopyranosyl ester; 1), kalidiunin (=3beta,23,29-trihydroxy-olean-12-en-28-methyl-oate; 2) and kalidiumoside D (=3beta,23,29-trihydroxyolean-12-en-28-oic acid-beta-D-glucopyranosyl ester; 3). The known compound was identified as 3beta,23,29-trihydroxy-olean-12-en-28-oic acid 4) through comparison of its spectral data with those reported in literature. Acid hydrolysis of both 2 and 3 yielded the known compound 4 providing a conclusive evidence of the proposed structures.
Shaheen Siddiqui
Bina
B
International Centre for Chemical Sciences, HEJ Research Institute of Chemistry and Dr Panjwani Center for Molecular Medicine and Drug Research, University of Karachi, Karachi, Pakistan. bina@khi.comsats.net.pk
Zhymabekovna Karzhaubekova
Zhanat
Z
Shahmanovna Burasheva
Gauhar
G
Adaibaevna Sultanova
Nurgyl
N
D000107:Acetylation; D019663:Chenopodiaceae / Q000737:chemistry*; D006868:Hydrolysis; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D008968:Molecular Conformation; D008970:Molecular Weight; D021241:Spectrometry, Mass, Electrospray Ionization; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet; D014315:Triterpenes / Q000737:chemistry