Influence of haemodialysis on high-sensitivity C-reactive protein, lipoprotein(a), apolipoproteins A and B.
OBJECTIVE
There is debate on the influence of haemodialysis (HD) on lipoprotein(a).


METHODS
Lp(a), apo A, apo B and high-sensitivity C-reactive protein (hs-CRP) were measured in 46 patients pre- and post-HD.


RESULTS
The median Lp(a) concentration significantly decreased post-HD (106 vs. 145 mg/L, p<0.001). No significant variations were observed for apo A, apo B and hs-CRP. Comparable results were observed with high- and low-flux membranes.


CONCLUSIONS
HD is effective in lowering Lp(a).
Lippi
Giuseppe
G
Sezione di Chimica Clinica, Dipartimento di Scienze Morfologico-Biomediche, Università degli Studi di Verona, Ospedale Policlinico G.B. Rossi, Piazzale Scuro, 10, 37121-Verona, Italy. ulippi@tin.it
Tessitore
Nicola
N
Salvagno
Gian Luca
GL
Bedogna
Valeria
V
Bassi
Antonella
A
Montagnana
Martina
M
Lupo
Antonio
A
Guidi
Gian Cesare
GC
D000368:Aged; D000369:Aged, 80 and over; D001053:Apolipoproteins / Q000097:blood*; D001054:Apolipoproteins A / Q000097:blood*; D001055:Apolipoproteins B / Q000097:blood*; D002097:C-Reactive Protein / Q000032:analysis*; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000097:blood / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D006435:Renal Dialysis