The pinholin of lambdoid phage 21: control of lysis by membrane depolarization.
The phage 21 holin, S(21), forms small membrane holes that depolarize the membrane and is designated as a pinholin, as opposed to large-hole-forming holins, like S(lambda). Pinholins require secreted SAR endolysins, a pairing that may represent an intermediate in the evolution of canonical holin-endolysin systems.
Park
Taehyun
T
Department of Biochemistry and Biophysics, Texas A&M University, 2128 TAMU, College Station, TX 77843-2128, USA.
Struck
Douglas K
DK
Dankenbring
Chelsey A
CA
Young
Ry
R
D001433:Bacteriolysis / Q000502:physiology*; D002462:Cell Membrane / Q000502:physiology; D003090:Coliphages / Q000502:physiology*; D010450:Endopeptidases / Q000502:physiology*; D004926:Escherichia coli / Q000821:virology*; D014764:Viral Proteins / Q000502:physiology*