title: Radiation necrosis of the brain after radiosurgery for vestibular schwannoma.
abstract: OBJECTIVE
  The objective of this study was to obtain a better understanding of radiation-induced brain necrosis after stereotactic radiation therapy for vestibular schwannomas.
  
  
  METHODS
  We conducted a retrospective case analysis.
  
  
  METHODS
  The study took place at a tertiary referral center.
  
  
  METHODS
  We report on the case of a patient treated with stereotactic radiation who developed radiation-induced necrosis of the ipsilateral temporal lobe.
  
  
  METHODS
  The various interventions in patients with radiation-induced necrosis include steroid treatment, decompression, and hyperbaric oxygen therapy; these are discussed briefly in this article. Owing to the limited symptoms in our patient, she was observed.
  
  
  METHODS
  The outcome measure that we evaluated was radiation-induced necrosis of the brain after stereotactic radiation therapy for a vestibular schwannoma.
  
  
  RESULTS
  Patients who undergo stereotactic radiation therapy for vestibular schwannomas are at risk for radiation-induced brain necrosis.
  
  
  CONCLUSIONS
  We support the development of a national database that would track the long-term complications of stereotactic radiation therapy to help patients make a more informed decision for the treatment of their vestibular schwannomas.
authors.affiliation: Department of Otolaryngology, University of California, Irvine Medical Center, Orange, CA 92868, USA. skullbasesurgery@yahoo.com
authors.forename: Hamid R
authors.initials: HR
authors.lastname: Djalilian
authors.forename: Aaron G
authors.initials: AG
authors.lastname: Benson
authors.forename: Kasra
authors.initials: K
authors.lastname: Ziai
authors.forename: Yalda
authors.initials: Y
authors.lastname: Safai
authors.forename: Kunal H
authors.initials: KH
authors.lastname: Thakkar
authors.forename: Mahmood F
authors.initials: MF
authors.lastname: Mafee
mesh_terms: D000328:Adult; D001930:Brain Injuries / Q000175:diagnosis / Q000209:etiology*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D009336:Necrosis / Q000209:etiology; D009464:Neuroma, Acoustic / Q000473:pathology / Q000601:surgery*; D011832:Radiation Injuries / Q000175:diagnosis / Q000209:etiology*; D016634:Radiosurgery / Q000009:adverse effects*; D013238:Stereotaxic Techniques