Role of acid-suppressing medications during a sustained outbreak of Salmonella enteritidis infection in a long-term care facility.
During an insidious outbreak of salmonellosis in a long-term care facility, residents who were treated with acid-suppressing medications were 8 times more likely than other residents to develop Salmonella infection. Among vulnerable populations, the risks and benefits of acid-suppressing medications should be considered carefully before use.
Bowen
Anna
A
Centers for Disease Control and Prevention, Atlanta, GA 30333, USA. aqb0@cdc.gov
Newman
Alexandra
A
Estivariz
Concepcion
C
Gilbertson
Norene
N
Archer
John
J
Srinivasan
Arjun
A
Lynch
Michael
M
Painter
John
J
D000368:Aged; D000369:Aged, 80 and over; D000863:Antacids / Q000009:adverse effects*; D000897:Anti-Ulcer Agents / Q000009:adverse effects*; D016022:Case-Control Studies; D003428:Cross Infection / Q000453:epidemiology; D004196:Disease Outbreaks; D005260:Female; D005759:Gastroenteritis / Q000209:etiology / Q000401:mortality; D006801:Humans; D007380:Intermediate Care Facilities; D008134:Long-Term Care; D008297:Male; D008875:Middle Aged; D012480:Salmonella Infections / Q000209:etiology* / Q000401:mortality; D012477:Salmonella enteritidis / Q000472:pathogenicity*; D014922:Wisconsin / Q000453:epidemiology