title: Effect of the benzylic structure of lignan on antioxidant activity.
abstract: The effect of the benzylic structure of lignan on antioxidant activity was evaluated. Secoisolariciresinol (1) and 3,4-bis(4-hydroxy-3-methoxybenzyl)tetrahydrofuran (2), which have two secondary benzylic positions without oxygen, showed the highest antioxidant activity. Optically active verrucosin (4) was synthesized for the first time in this experiment.
authors.affiliation: Faculty of Agriculture, Ehime University, 3-5-7 Tarumi, Matsuyama, Ehime 790-8566, Japan. syamauch@agr.ehime-u.ac.jp
authors.forename: Satoshi
authors.initials: S
authors.lastname: Yamauchi
authors.forename: Takuya
authors.initials: T
authors.lastname: Sugahara
authors.forename: Junko
authors.initials: J
authors.lastname: Matsugi
authors.forename: Tatsushi
authors.initials: T
authors.lastname: Someya
authors.forename: Toshiya
authors.initials: T
authors.lastname: Masuda
authors.forename: Taro
authors.initials: T
authors.lastname: Kishida
authors.forename: Koichi
authors.initials: K
authors.lastname: Akiyama
authors.forename: Masafumi
authors.initials: M
authors.lastname: Maruyama
mesh_terms: D000975:Antioxidants / Q000737:chemistry*; D001554:Benzene / Q000737:chemistry*; D005609:Free Radicals / Q000737:chemistry; D017705:Lignans / Q000138:chemical synthesis / Q000737:chemistry*; D015394:Molecular Structure; D013482:Superoxide Dismutase / Q000737:chemistry