Small cell carcinoma of the cervix: a case report.
Small cell carcinoma of the uterine cervix accounts for 1-3% of all cervix cancers. It is an aggressive disease with a poor prognosis. To date, no effective treatment protocol has been determined. Surgery, radiotherapy, and chemotherapy have been used either alone or in combination. Recent data suggests that survival in patients with early staged small cell carcinoma of the cervix is better with surgery combined with chemo-radiotherapy. Here, we presented two patients with stage IB1 small cell carcinoma of the uterine cervix. For both patients, definitive surgery was performed with pelvic and para-aortic lymphadenectomy. Subsequently, they were treated with pelvic external radiotherapy and high-dose-rate intracavitary brachytherapy with concurrent cisplatin based chemotherapy. They were alive with no evidence of disease at 91 and 65 months, respectively.
Korcum
Aylin Fidan
AF
Department of Radiation Oncology, Akdeniz University, School of Medicine, 07070, Antalya, Turkey. aylinfk07@yahoo.com
Aksu
Gamze
G
Bozcuk
Hakan
H
Pestereli
Elif
E
Simsek
Tayup
T
D000328:Adult; D000972:Antineoplastic Agents, Phytogenic / Q000627:therapeutic use; D001918:Brachytherapy; D018288:Carcinoma, Small Cell / Q000473:pathology / Q000628:therapy*; D002584:Cervix Uteri / Q000473:pathology; D002945:Cisplatin / Q000008:administration & dosage; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D011247:Pregnancy; D002583:Uterine Cervical Neoplasms / Q000473:pathology / Q000628:therapy*