Total synthesis of the L-hexoses.
Enantiomerically pure polyhydroxylated natural products are synthesized by using a reiterative two-carbon extension cycle consisting of four steps. The generality and efficiency of this methodology are demonstrated in the total synthesis of all eight L-hexoses.
Ko
S Y
SY
Lee
A W
AW
Masamune
S
S
Reed
L A
LA
Sharpless
K B
KB
Walker
F J
FJ