Daphnogirins A and B, two biflavones from Daphne giraldii.
Two new biflavonoids, daphnogirins A (1) and B (2), were obtained from the roots of Daphne giraldii. Their structures were established on the basis of the spectral data and X-ray diffraction data of the co-crystal of 1 and 2. Daphnogrins A and B have the same configuration at C-1 and opposite configurations at C-16 and C-17. Oxygen radical scavenging assay has indicated that they are of significant antioxidative activity.
Zhou
Guang-Xiong
GX
College of Pharmacy, Jinan University, Guangzhou, China. guangxzh@hotmail.com
Jiang
Ren-Wang
RW
Cheng
Yan
Y
Ye
Wen-Cai
WC
Shi
Jian-Gong
JG
Gong
Ning-Bo
NB
Lu
Yang
Y
D000975:Antioxidants / Q000737:chemistry; D002839:Chromans / Q000737:chemistry; D018360:Crystallography, X-Ray; D032364:Daphne / Q000737:chemistry*; D047309:Flavones / Q000737:chemistry*; D019793:Fluorescein / Q000737:chemistry; D016166:Free Radical Scavengers / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D008968:Molecular Conformation; D024301:Plant Bark / Q000737:chemistry; D018547:Plant Stems / Q000737:chemistry; D017382:Reactive Oxygen Species / Q000737:chemistry; D016339:Spectrometry, Mass, Fast Atom Bombardment; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet