Androstane and monoterpene glucoside sinapoyl ester from Cynanchum amplexicaule SIEB. et ZUCC.
A new androstane, 17beta-hydroxy-androsta-4,6,15-trien-3-one (1) and a new monoterpene glucoside sinapoyl ester, (3R)-8-hydroxylinalool 3,8-di-O-beta-D-(6'-O-E-sinapoyl)glucopyranoside (2) were isolated from the roots of Cynanchum amplexicaule SIEB. et ZUCC. (Asclepiadaceae), along with two known monoterpenes, (3R)-8-hydroxylinalool (3) and (6R)-menthiafolic acid (4). Their structures were elucidated on the basis of analyses of physical, chemical, and spectral data.
Chen
Huan
H
School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, China.
Zhou
Yu-Zhi
YZ
Qiao
Li
L
Cao
Jia-Qing
JQ
Yao
Yao
Y
Hua
Hui-Ming
HM
Pei
Yue-Hu
YH
D000731:Androstanes / Q000737:chemistry* / Q000302:isolation & purification; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D002725:Chloroform / Q000737:chemistry; D031105:Cynanchum / Q000737:chemistry*; D005960:Glucosides / Q000737:chemistry* / Q000302:isolation & purification; D006868:Hydrolysis; D009682:Magnetic Resonance Spectroscopy; D039821:Monoterpenes / Q000737:chemistry* / Q000302:isolation & purification; D009904:Optical Rotation; D018517:Plant Roots / Q000737:chemistry; D012997:Solvents; D016339:Spectrometry, Mass, Fast Atom Bombardment; D013055:Spectrophotometry, Infrared