title: 5'-halogenated analogs of oxymorphindole.
abstract: The presence of a 6,7-fused indole group in the indolomorphinans was considered to be responsible for the delta opioid selectivity for this class of ligands. Herein is shown that 5'-halogenated analogs of oxymorphindole are opioids with little selectivity for delta receptors over mu opioid receptors.
authors.affiliation: Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy, 20 Penn Street, Baltimore, MD 21201, USA.
authors.forename: Matthew D
authors.initials: MD
authors.lastname: Metcalf
authors.forename: Andrew
authors.initials: A
authors.lastname: Coop
mesh_terms: D006219:Halogens / Q000737:chemistry*; D009025:Morpholines / Q000737:chemistry* / Q000494:pharmacology; D017465:Receptors, Opioid, delta / Q000187:drug effects; D017450:Receptors, Opioid, mu / Q000187:drug effects