title: Tako-tsubo cardiomyopathy associated with brain metastasis of seminoma in a patient with chronic kidney disease.
abstract: We report a case of tako-tsubo cardiomyopathy associated with brain metastasis of seminoma. This disease is characterized by transient cardiac wall motion abnormalities, electrocardiographic changes and minimal myocardial enzymatic release. During the hospital days, acute congestive heart failure suddenly appeared. The electrocardiogram showed a ST segment elevation in V1-3 and a giant negative T wave in I, aVL, aVF and V3-6. The echocardiogram revealed left ventricular dysfunction with severe hypokinesis to akinesis of anterior and apical wall regions, and hyperkinesis of the basal wall despite the lack of cardiac enzymatic abnormalities. With proper treatment, the patient's overall condition, wall motion and electrocardiographic abnormalities greatly improved.
authors.affiliation: Division of Nephrology and Dialysis Center, Kobe University Graduate School of Medicine. hideki-f@tg7.so-net.ne.jp
authors.forename: Hideki
authors.initials: H
authors.lastname: Fujii
authors.forename: Takaya
authors.initials: T
authors.lastname: Abe
authors.forename: Michio
authors.initials: M
authors.lastname: Umezu
authors.forename: Masafumi
authors.initials: M
authors.lastname: Fukagawa
mesh_terms: D001932:Brain Neoplasms / Q000150:complications* / Q000556:secondary; D009202:Cardiomyopathies / Q000150:complications*; D006801:Humans; D007676:Kidney Failure, Chronic / Q000150:complications*; D008297:Male; D008875:Middle Aged; D018239:Seminoma / Q000150:complications* / Q000556:secondary; D013736:Testicular Neoplasms / Q000150:complications* / Q000473:pathology