title: Differences in developing intestinal microbiota between allergic and non-allergic infants: a pilot study in Japan.
abstract: The bacterial compositions of feces were monitored in the first 2 months for 15 infants born in Japan, including eight subjects who developed allergy by the age of 2 years. Primer sets targeting six predominant bacterial groups in the infant intestine, Bacteroidaceae, Enterobacteriaceae, bifidobacteria, enterococci, lactobacilli, and the Clostridium perfringens group, were used for real-time PCR to quantitate each population in the feces. The population of Bacteroidaceae was significantly higher in the allergic group at the ages of 1 month (P=0.03) and 2 months (P=0.05) than in the non-allergic group, while no statistically significant difference was observed for the other bacterial populations.
authors.affiliation: Department of Bioscience and Biotechnology, Faculty of Agriculture, Graduate School, Kyushu University, 6-10-1 Hakozaki, Higashi-ku, Fukuoka 812-8581, Japan.
authors.forename: Prapa
authors.initials: P
authors.lastname: Songjinda
authors.forename: Jiro
authors.initials: J
authors.lastname: Nakayama
authors.forename: Atsushi
authors.initials: A
authors.lastname: Tateyama
authors.forename: Shigemitsu
authors.initials: S
authors.lastname: Tanaka
authors.forename: Mina
authors.initials: M
authors.lastname: Tsubouchi
authors.forename: Chikako
authors.initials: C
authors.lastname: Kiyohara
authors.forename: Taro
authors.initials: T
authors.lastname: Shirakawa
authors.forename: Kenji
authors.initials: K
authors.lastname: Sonomoto
mesh_terms: D006801:Humans; D006967:Hypersensitivity / Q000382:microbiology*; D007223:Infant; D007422:Intestines / Q000382:microbiology*; D010865:Pilot Projects; D012336:RNA, Ribosomal, 16S / Q000235:genetics