title: Biomimetic total synthesis of proto-daphniphylline.
abstract: Proto-daphniphylline, the imputed biogenetic parent of the Daphniphyllum alkaloids, has been assembled in a biogenetically styled laboratory synthesis in which a pentacyclization process is the fundamental synthetic stratagem. This extraordinary transformation involves the formation of six (r-bonds under the influence of three elementary reagents-potassium hydroxide, anmnonia, and acetic acid. The facility of the process adds credibility to the previous speculation that a similar process is an important step in the biosynthesis of the Daphniphyllum alkaloids.
authors.forename: S
authors.initials: S
authors.lastname: Piettre
authors.forename: C H
authors.initials: CH
authors.lastname: Heathcock