Acute myeloid leukaemia presenting as galactorrhoea.
The clinical presentation of acute myeloid leukaemia is variable. We report a 40-year-old woman who presented with a 1-month history of galactorrhoea with an elevated prolactin level. The blood counts were normal, but she was found to have acute myeloid leukaemia with monocytic differentiation. The serum prolactin level normalized after chemotherapy. In the absence of evidence of CNS involvement, the hyperprolactinaemia is presumed to be a paraneoplastic phenomenon. We discuss the potential mechanism of prolactin production in this case.
Muslahi
M A
MA
Department of Clinical Haematology and Bone Marrow Transplantation, Royal Adelaide Hospital, North Terrace, Adelaide, SA, Australia. almuslahimnr@hotmail.com
Ross
D M
DM
D000328:Adult; D005260:Female; D005687:Galactorrhea / Q000209:etiology*; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000150:complications* / Q000378:metabolism; D011388:Prolactin / Q000378:metabolism