title: Health-related quality of life in older adults at risk for disability.
abstract: BACKGROUND
  The number of older adults living in the United States continues to increase, and recent research has begun to target interventions to older adults who have mobility limitations and are at risk for disability. The objective of this study is to describe and examine correlates of health-related quality of life in this population subgroup using baseline data from a larger intervention study.
  
  
  METHODS
  The Lifestyle Interventions and Independence for Elders-Pilot study (LIFE-P) was a randomized controlled trial that compared a physical activity intervention to a non-exercise educational intervention among 424 older adults at risk for disability. Baseline data (collected in April-December 2004, analyzed in 2006) included demographics, medical history, the Quality of Well-Being Scale (QWB-SA), a timed 400-m walk, and the Short Physical Performance Battery (SPPB). Descriptive health-related quality of life (HRQOL) data are presented. Hierarchical linear regression models were used to examine correlates of HRQOL.
  
  
  RESULTS
  The mean QWB-SA score for the sample was 0.630 on an interval scale ranging from 0.0 (death) to 1.0 (asymptomatic, optimal functioning). The mean of 0.630 is 0.070 lower than a comparison group of healthy older adults. The variables associated with lower HRQOL included white ethnicity, more comorbid conditions, slower 400-m walk times, and lower SPPB balance and chair stand scores.
  
  
  CONCLUSIONS
  Older adults who are at risk for disability had reduced HRQOL. Surprisingly, however, mobility was a stronger correlate of HRQOL than an index of comorbidity, suggesting that interventions addressing mobility limitations may provide significant health benefits to this population.
authors.affiliation: Health Services Research and Development Unit, VA San Diego Healthcare System, San Diego, California 92161, USA. egroessl@ucsd.edu
authors.forename: Erik J
authors.initials: EJ
authors.lastname: Groessl
authors.forename: Robert M
authors.initials: RM
authors.lastname: Kaplan
authors.forename: W Jack
authors.initials: WJ
authors.lastname: Rejeski
authors.forename: Jeffrey A
authors.initials: JA
authors.lastname: Katula
authors.forename: Abby C
authors.initials: AC
authors.lastname: King
authors.forename: Georita
authors.initials: G
authors.lastname: Frierson
authors.forename: Nancy W
authors.initials: NW
authors.lastname: Glynn
authors.forename: Fang-Chi
authors.initials: FC
authors.lastname: Hsu
authors.forename: Michael
authors.initials: M
authors.lastname: Walkup
authors.forename: Marco
authors.initials: M
authors.lastname: Pahor
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D015897:Comorbidity; D004185:Disability Evaluation; D005006:Ethnicity; D005260:Female; D015577:Geriatric Assessment; D006293:Health Promotion; D006306:Health Surveys; D006801:Humans; D016014:Linear Models; D008297:Male; D051346:Mobility Limitation; D011788:Quality of Life; D012307:Risk Factors; D014481:United States; D016138:Walking