title: The pinholin of lambdoid phage 21: control of lysis by membrane depolarization.
abstract: The phage 21 holin, S(21), forms small membrane holes that depolarize the membrane and is designated as a pinholin, as opposed to large-hole-forming holins, like S(lambda). Pinholins require secreted SAR endolysins, a pairing that may represent an intermediate in the evolution of canonical holin-endolysin systems.
authors.affiliation: Department of Biochemistry and Biophysics, Texas A&M University, 2128 TAMU, College Station, TX 77843-2128, USA.
authors.forename: Taehyun
authors.initials: T
authors.lastname: Park
authors.forename: Douglas K
authors.initials: DK
authors.lastname: Struck
authors.forename: Chelsey A
authors.initials: CA
authors.lastname: Dankenbring
authors.forename: Ry
authors.initials: R
authors.lastname: Young
mesh_terms: D001433:Bacteriolysis / Q000502:physiology*; D002462:Cell Membrane / Q000502:physiology; D003090:Coliphages / Q000502:physiology*; D010450:Endopeptidases / Q000502:physiology*; D004926:Escherichia coli / Q000821:virology*; D014764:Viral Proteins / Q000502:physiology*