[Systematic diagnosis of erythrocytosis].
Erythrocytosis is a phenomenon with life-threatening complications and a broad differential diagnosis. Erythrocytosis is usually secondary to a cardiopulmonary condition leading to a low arterial oxygen tension. A probable diagnosis can often be made on the basis of the history, physical examination, a measurement of the peripheral oxygen saturation, and simple laboratory tests. The differential diagnosis can be narrowed down by a determination of the erythropoietin concentration and the JAK2 mutation. If the erythrocytosis is found to be non-physiological, then reduction of the haematocrit via bloodletting and, depending on the diagnosis, treatment with acetylsalicylic acid are indicated.
de Heer
K
K
Tergooiziekenhuizen, locatie Blaricum, afd. Interne Geneeskunde, Blaricum. koen@de-heer.eu
Silbermann
M H
MH
Koene
H R
HR
Biemond
B J
BJ
Muller
H P
HP
van Oers
M H J
MH
D001241:Aspirin / Q000627:therapeutic use; D001815:Bloodletting; D003937:Diagnosis, Differential; D004921:Erythropoietin / Q000097:blood*; D006801:Humans; D053614:Janus Kinase 2 / Q000235:genetics; D010100:Oxygen / Q000097:blood*; D011086:Polycythemia / Q000175:diagnosis* / Q000235:genetics / Q000628:therapy