title: Candida albicans biofilms produce more secreted aspartyl protease than the planktonic cells.
abstract: By using a simple, low-cost system of polystyrene centrifuge tubes we compared the secreted aspartyl proteases (Saps) secretion during the biphasic growth modes of Candida albicans using twenty-one clinical isolates. Our results indicate that biofilms of C. albicans consistently secrete more Saps than their planktonic counterparts.
authors.affiliation: Laboratory of Stomatology, Faculty of Dentistry, Pontifical Catholic University of Paraná, Brazil.
authors.forename: Aline
authors.initials: A
authors.lastname: Mendes
authors.forename: Alinne Ulbrich
authors.initials: AU
authors.lastname: Mores
authors.forename: Alessandra Paula
authors.initials: AP
authors.lastname: Carvalho
authors.forename: Rosimeire Takaki
authors.initials: RT
authors.lastname: Rosa
authors.forename: Lakshman Perera
authors.initials: LP
authors.lastname: Samaranayake
authors.forename: Edvaldo Antonio Ribeiro
authors.initials: EA
authors.lastname: Rosa
mesh_terms: D016282:Aspartic Acid Endopeptidases / Q000378:metabolism*; D018441:Biofilms; D018533:Biomass; D002176:Candida albicans / Q000201:enzymology* / Q000254:growth & development / Q000502:physiology; D008928:Mitochondria / Q000201:enzymology; D013778:Tetrazolium Salts