title: Rumphellolides A-F, six new caryophyllane-related derivatives from the Formosan Gorgonian coral Rumphella antipathies.
abstract: Six new caryophyllane-related natural products, including two carboxylated sesquiterpenoids, rumphellolides A (1) and B (2), and four norsesquiterpene alcohols, rumphellolides C-F (3-6), were isolated from the Formosan gorgonian coral Rumphella antipathies. The structures of the above new natural products were established on the basis of extensive spectral data analysis. Rumphellolides A (1), D (4), E (5), and F (6) showed weak antibacterial activity.
authors.affiliation: National Museum of Marine Biology and Aquarium, Checheng, Pingtung, Taiwan, ROC. pjsung@nmmba.gov.tw
authors.forename: Ping-Jyun
authors.initials: PJ
authors.lastname: Sung
authors.forename: Li-Fan
authors.initials: LF
authors.lastname: Chuang
authors.forename: Jimmy
authors.initials: J
authors.lastname: Kuo
authors.forename: Jih-Jung
authors.initials: JJ
authors.lastname: Chen
authors.forename: Tung-Yung
authors.initials: TY
authors.lastname: Fan
authors.forename: Jan-Jung
authors.initials: JJ
authors.lastname: Li
authors.forename: Lee-Shing
authors.initials: LS
authors.lastname: Fang
authors.forename: Wei-Hsien
authors.initials: WH
authors.lastname: Wang
mesh_terms: D000818:Animals; D037421:Anthozoa / Q000737:chemistry*; D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology*; D004926:Escherichia coli / Q000187:drug effects; D005612:Freeze Drying; D009682:Magnetic Resonance Spectroscopy; D008826:Microbial Sensitivity Tests; D008968:Molecular Conformation; D011550:Pseudomonas aeruginosa / Q000187:drug effects; D012717:Sesquiterpenes / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology*; D021241:Spectrometry, Mass, Electrospray Ionization; D013211:Staphylococcus aureus / Q000187:drug effects; D014736:Vibrio parahaemolyticus / Q000187:drug effects