title: Whole-body MR angiography using variable density sampling and dual-injection bolus-chase acquisition.
abstract: Conventional bolus-chase acquisition generates peripheral runoff images using a single injection of the contrast material. Low spatial resolution, small slice coverage and venous contamination are major problems especially in the distal stations. A technique is presented herein in which whole-body magnetic resonance angiography is performed using a dual-contrast-injection four-station acquisition protocol. Bolus sharing was performed between two stations: the abdomen and calf stations share the first bolus injection, while the thorax and thigh stations share the second bolus injection. The combination of variable density sampling and elliptical centric acquisition order was applied to the abdomen and thorax stations. The scan time was extended to generate high spatial resolution arterial phase images with broad slice coverage for the calf and thigh stations. The feasibility of this technique was demonstrated using phantom and in vivo human volunteer studies.
authors.affiliation: Department of Medical Physics and Radiology, University of Wisconsin, Madison, WI 53792, USA. jiangdu@ucsd.edu <jiangdu@ucsd.edu>
authors.forename: Jiang
authors.initials: J
authors.lastname: Du
authors.forename: Frank R
authors.initials: FR
authors.lastname: Korosec
authors.forename: Yijing
authors.initials: Y
authors.lastname: Wu
authors.forename: Thomas M
authors.initials: TM
authors.lastname: Grist
authors.forename: Charles A
authors.initials: CA
authors.lastname: Mistretta
mesh_terms: D003287:Contrast Media / Q000008:administration & dosage*; D019786:Gadolinium DTPA / Q000008:administration & dosage*; D006801:Humans; D021621:Imaging, Three-Dimensional; D007866:Leg / Q000098:blood supply*; D018810:Magnetic Resonance Angiography / Q000379:methods*; D019047:Phantoms, Imaging; D051598:Whole Body Imaging