title: Two therapeutic challenges: periocular and genital vitiligo in children successfully treated with pimecrolimus cream.
abstract: Vitiligo is characterized by the selective destruction of melanocytes resulting in patches of skin depigmentation. Vitiligo is a therapeutic challenge. Eyebrows, eyelids and genital vitiligo are a therapeutic dilemma, especially in children. The possible side effects of topical corticosteroids and the difficulties for choosing any other adequate treatment option are a major concern. We present two children, one with vitiligo of the eyelids and the other with genital vitiligo, both treated with pimecrolimus 1% cream with almost full repigmentation of the lesions, showing pimecrolimus could be an adequate option for the treatment of vitiligo for these special vitiligo areas in children.
authors.affiliation: Universidade Católica de Brasília and Instituto Saint Louis de Brasília, Brazilia, Brazil. rmsl@terra.com.br
authors.forename: Rubens Marcelo
authors.initials: RM
authors.lastname: Souza Leite
authors.forename: Adriana Aragão
authors.initials: AA
authors.lastname: Craveiro Leite
mesh_terms: D000287:Administration, Topical; D002648:Child; D005143:Eyelids / Q000473:pathology; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D008297:Male; D010413:Penis / Q000473:pathology; D012074:Remission Induction; D012867:Skin / Q000473:pathology; D016559:Tacrolimus / Q000031:analogs & derivatives* / Q000627:therapeutic use; D014820:Vitiligo / Q000188:drug therapy* / Q000473:pathology