Immunologic approaches to composite tissue allograft.
This article discusses the immunologic principles and the most promising immunologic approaches for composite tissue allograft tolerance. We have previously reviewed some of the pharmacologic approaches for composite tissue allo-transplantation. In this review, we will summarize the range of options that may address the challenge of transplantation in reconstructive surgery.
Taieb
Aurèle
A
School of Medicine, University of Pittsburgh, Pittsburgh, PA 15261, USA.
Clavijo-Alvarez
Julio A
JA
Hamad
Giselle G
GG
Lee
W P Andrew
WP
D000818:Animals; D000911:Antibodies, Monoclonal / Q000627:therapeutic use; D046528:Chimerism; D006650:Histocompatibility Testing; D006801:Humans; D008285:Major Histocompatibility Complex / Q000276:immunology; D016378:Tissue Transplantation; D023001:Transplantation Tolerance; D014184:Transplantation, Homologous