title: The range and demographics of salivary gland tumours diagnosed in a UK population.
abstract: Salivary gland tumours are relatively rare and comprise a diverse range of neoplasms. The aim of this study was to determine the range and demographics of all histologically diagnosed salivary tumours in a European population. All entries for salivary gland tumours from 1974 to 2005 inclusive were retrieved and analysed for each diagnosis including number of specimens, male:female ratio and age range. These data were then analysed for the distribution of benign and malignant salivary tumours in major and minor salivary glands. 58,880 specimens were received; of these, 741 cases (1.3% of all specimens) were diagnosed as salivary gland tumours with a male to female ratio of 0.7:1. There were 481 (64.9%) benign and 260 (35.1%) malignant neoplasms, with the most common tumours being pleomorphic adenoma and mucoepidermoid carcinoma, respectively. Our study provides demographic data on a large series of salivary gland tumours in a European population. Accurate diagnosis is essential as salivary lesions have diverse clinical and prognostic outcomes. This study has confirmed that some tumours have a predilection for certain sites and that the risk of malignant disease is also greater at specific sites within the oral cavity.
authors.affiliation: Department of Oral Pathology, School of Clinical Dentistry, University of Sheffileld, Claremont Crescent, Sheffield, S10 2TA, UK. Adam.Jones@sheffield.ac.uk
authors.forename: A V
authors.initials: AV
authors.lastname: Jones
authors.forename: G T
authors.initials: GT
authors.lastname: Craig
authors.forename: P M
authors.initials: PM
authors.lastname: Speight
authors.forename: C D
authors.initials: CD
authors.lastname: Franklin
mesh_terms: D000235:Adenolymphoma / Q000453:epidemiology / Q000473:pathology; D000236:Adenoma / Q000453:epidemiology / Q000473:pathology; D008949:Adenoma, Pleomorphic / Q000453:epidemiology / Q000473:pathology; D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D018277:Carcinoma, Mucoepidermoid / Q000453:epidemiology / Q000473:pathology; D002648:Child; D004739:England / Q000453:epidemiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012468:Salivary Gland Neoplasms / Q000453:epidemiology* / Q000473:pathology; D012470:Salivary Glands, Minor; D017678:Sex Distribution