Characterization of antibacterial nanoparticles from the scallop, Ptinopecten yessoensis.
To develop a new drug delivery system, antibacterial 50-900 nm nanoparticles of shell and internal organs from scallops collected off Huksan-Island, Korea, were prepared by dry grind technology respectively. The diameters, identities, and conformations of the scallop shell and internal organ particles were determined with a particle-size analyzer and by X-ray powder diffraction (XRD), scanning electron microscopy (SEM), and Raman spectroscopy. The antibacterial properties of the nanoparticles from scallop shell were investigated in the absence and the presence of scallop-shell extract. Bacterial growth was reduced with the supernatant of the nanoparticle scallop-shell extract. Also, the nanoparticles from scallop shell were much more effective as a skin softener than was powder. These facts provide us with guidelines for the study of the size-dependent properties of functional materials as well as for further applications to drug delivery systems (DDSs) and cosmetic raw materials.
Jeong
Mi Suk
MS
Research Center for Advanced Science and Technology, Dongseo University, Busan 617-716, Korea.
Park
Jeong Soon
JS
Song
Seong Hwan
SH
Jang
Se Bok
SB
D000818:Animals; D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000633:toxicity*; D050296:Microbial Viability / Q000187:drug effects; D008855:Microscopy, Electron, Scanning; D053758:Nanoparticles / Q000737:chemistry* / Q000648:ultrastructure*; D010316:Particle Size; D049897:Pectinidae / Q000737:chemistry*; D013212:Staphylococcus epidermidis / Q000187:drug effects; D014961:X-Ray Diffraction