title: Eosinophilic ulcer of the oral mucosa versus squamous cell carcinoma.
abstract: Eosinophilic ulcer of the oral mucosa is a benign, rare, self-limiting, and generally asymptomatic lesion that shows spontaneous regression. Its etiopathogenesis is still uncertain, but trauma seems to play a fundamental role in the occurrence of this tumor. Clinically, this lesion manifests as an isolated ulcer preferentially located on the tongue, showing a raised and indurated border in addition to a white or yellowish bed. Microscopically, eosinophilic ulcer is characterized by an inflammatory infiltrate rich in leukocytes. Since these lesions show spontaneous cure, treatment becomes unnecessary, but in certain cases, cure is obtained by excision of the ulcer during biopsy. In these cases, the differential diagnosis with squamous cell carcinoma is made. A case of very small eosinophilic ulcer of the oral mucosa located on the lateral border of the tongue is presented.
authors.affiliation: Department of Stomatology, Bauru School of Dentistry, University of São Paulo, São Paulo, Brazil. dedugoncales@aol.com
authors.forename: Eduardo Sanches
authors.initials: ES
authors.lastname: Gonçales
authors.forename: Izabel Fischer
authors.initials: IF
authors.lastname: Rubira-Bullen
authors.forename: Cássia Maria Fischer
authors.initials: CM
authors.lastname: Rubira
authors.forename: Marta
authors.initials: M
authors.lastname: Miyazawa
authors.forename: Luis Eduardo Montenegro
authors.initials: LE
authors.lastname: Chinellato
authors.forename: Alberto
authors.initials: A
authors.lastname: Consolaro
mesh_terms: D002294:Carcinoma, Squamous Cell / Q000473:pathology*; D003937:Diagnosis, Differential; D004802:Eosinophilia / Q000473:pathology* / Q000601:surgery; D005260:Female; D006801:Humans; D008875:Middle Aged; D009062:Mouth Neoplasms / Q000473:pathology*; D019226:Oral Ulcer / Q000473:pathology* / Q000601:surgery; D014060:Tongue Diseases / Q000473:pathology* / Q000601:surgery