title: Utility of antenatal HIV surveillance data to evaluate prevention of mother-to-child HIV transmission programs in resource-limited settings.
abstract: Prevention of mother-to-child human immunodeficiency virus (HIV) transmission (PMTCT) programs are expanding in resource-limited countries and are increasingly implemented in antenatal clinics (ANC) in which HIV sentinel surveillance is conducted. ANC sentinel surveillance data can be used to evaluate the first visit of a pregnant woman to PMTCT programs. We analyzed data from Kenya and Ethiopia, where information on PMTCT test acceptance was collected on the 2005 ANC sentinel surveillance forms. For Zimbabwe, we compared the 2005 ANC sentinel surveillance data to the PMTCT program data. ANC surveillance data allowed us to calculate the number of HIV-positive women not participating in the PMTCT program. The percentage of HIV-positive women missed by the PMTCT program was 17% in Kenya, 57% Ethiopia, and 59% Zimbabwe. The HIV prevalence among women participating in PMTCT differed from women who did not. ANC sentinel surveillance can be used to evaluate and improve the first encounter in PMTCT programs. Countries should collect PMTCT-related program data through ANC surveillance to strengthen the PMTCT program.
authors.affiliation: Centers for Disease Control and Prevention/National Center for HIV, Hepatitis, STD, and TB Prevention/Global AIDS Program, Atlanta, GA, USA. obolu@cdc.gov
authors.forename: Omotayo
authors.initials: O
authors.lastname: Bolu
authors.forename: Abhijeet
authors.initials: A
authors.lastname: Anand
authors.forename: Andrea
authors.initials: A
authors.lastname: Swartzendruber
authors.forename: Wolfgang
authors.initials: W
authors.lastname: Hladik
authors.forename: Lawrence H
authors.initials: LH
authors.lastname: Marum
authors.forename: Abdullahi Ahmed
authors.initials: AA
authors.lastname: Sheikh
authors.forename: Aseged
authors.initials: A
authors.lastname: Woldu
authors.forename: Shabbir
authors.initials: S
authors.lastname: Ismail
authors.forename: Agnes
authors.initials: A
authors.lastname: Mahomva
authors.forename: Stacie
authors.initials: S
authors.lastname: Greby
authors.forename: Keith
authors.initials: K
authors.lastname: Sabin
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000453:epidemiology / Q000517:prevention & control / Q000635:transmission*; D003906:Developing Countries; D005002:Ethiopia / Q000453:epidemiology; D005260:Female; D006295:Health Resources / Q000600:supply & distribution*; D006801:Humans; D018445:Infectious Disease Transmission, Vertical / Q000517:prevention & control*; D007630:Kenya / Q000453:epidemiology; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000453:epidemiology; D015995:Prevalence; D018571:Sentinel Surveillance; D015030:Zimbabwe / Q000453:epidemiology