title: Inflammatory pseudotumors of the pancreas and liver with infiltration of IgG4-positive plasma cells.
abstract: Recently, it has been reported that autoimmune pancreatitis (AIP) can be complicated with various extrapancreatic lesions. Here, we report a very rare case of pancreatic and hepatic inflammatory pseudotumor (IPT) with the infiltration of IgG4-positive plasmacytes. The patient showed pancreatic and hepatic masses with elevated levels of serum IgG4. Endoscopic retrograde cholangiopancreatography revealed narrowing of the intrapancreatic bile duct. Fluorine-18fluorodeoxyglucose positron emission tomography suggested pancreatic cancer with hepatic metastasis. Histopathologic findings showed fibrosis and infiltration of IgG4-positive plasmacytes, suggesting IPT. The present case suggests a possible common mechanism in the development of AIP and IPT of the liver.
authors.affiliation: Third Department of Internal Medicine, Kansai Medical University, Moriguchi. uchidak@hirakata.kmu.ac.jp
authors.forename: Kazushige
authors.initials: K
authors.lastname: Uchida
authors.forename: Sohei
authors.initials: S
authors.lastname: Satoi
authors.forename: Hideaki
authors.initials: H
authors.lastname: Miyoshi
authors.forename: Daisaku
authors.initials: D
authors.lastname: Hachimine
authors.forename: Tsukasa
authors.initials: T
authors.lastname: Ikeura
authors.forename: Masaaki
authors.initials: M
authors.lastname: Shimatani
authors.forename: Mitsunobu
authors.initials: M
authors.lastname: Matsushita
authors.forename: Makoto
authors.initials: M
authors.lastname: Takaoka
authors.forename: Soichiro
authors.initials: S
authors.lastname: Takai
authors.forename: Kiyoshi
authors.initials: K
authors.lastname: Ashida
authors.forename: Kazuichi
authors.initials: K
authors.lastname: Okazaki
mesh_terms: D001327:Autoimmune Diseases / Q000175:diagnosis / Q000276:immunology; D006104:Granuloma, Plasma Cell / Q000175:diagnosis* / Q000276:immunology; D006801:Humans; D007074:Immunoglobulin G / Q000276:immunology*; D008107:Liver Diseases / Q000175:diagnosis* / Q000276:immunology; D008297:Male; D008875:Middle Aged; D010182:Pancreatic Diseases / Q000175:diagnosis* / Q000276:immunology; D010195:Pancreatitis / Q000175:diagnosis / Q000276:immunology; D010950:Plasma Cells / Q000473:pathology*; D012075:Remission, Spontaneous