A chitin-binding lectin from stinging nettle rhizomes with antifungal properties.
Rhizomes of stinging nettle contain a small-sized lectin that exhibits binding specificity toward chitin. This lectin inhibits growth of several phytopathogenic and saprophytic chitin-containing fungi in vitro. The antifungal action of the nettle lectin differs from the action of chitinases, which are a ubiquitous class of antifungal plant proteins. Moreover, the nettle lectin acts synergistically with chitinase in inhibiting fungal growth. The nettle lectin may be a promising candidate for possible applications in the genetic engineering of disease-resistant crops.
Broekaert
W F
WF
VAN Parijs
J
J
Leyns
F
F
Joos
H
H
Peumans
W J
WJ