title: Letter to the editor of Biometrics.
authors.forename: Colin B
authors.initials: CB
authors.lastname: Begg
mesh_terms: D019313:BRCA1 Protein / Q000235:genetics; D024682:BRCA2 Protein / Q000235:genetics; D016022:Case-Control Studies; D005192:Family Health; D005838:Genotype; D006801:Humans; D016013:Likelihood Functions; D008487:Medical History Taking; D015233:Models, Statistical; D009154:Mutation; D009369:Neoplasms / Q000175:diagnosis; D016016:Proportional Hazards Models; D012306:Risk