title: Androstane and monoterpene glucoside sinapoyl ester from Cynanchum amplexicaule SIEB. et ZUCC.
abstract: A new androstane, 17beta-hydroxy-androsta-4,6,15-trien-3-one (1) and a new monoterpene glucoside sinapoyl ester, (3R)-8-hydroxylinalool 3,8-di-O-beta-D-(6'-O-E-sinapoyl)glucopyranoside (2) were isolated from the roots of Cynanchum amplexicaule SIEB. et ZUCC. (Asclepiadaceae), along with two known monoterpenes, (3R)-8-hydroxylinalool (3) and (6R)-menthiafolic acid (4). Their structures were elucidated on the basis of analyses of physical, chemical, and spectral data.
authors.affiliation: School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, China.
authors.forename: Huan
authors.initials: H
authors.lastname: Chen
authors.forename: Yu-Zhi
authors.initials: YZ
authors.lastname: Zhou
authors.forename: Li
authors.initials: L
authors.lastname: Qiao
authors.forename: Jia-Qing
authors.initials: JQ
authors.lastname: Cao
authors.forename: Yao
authors.initials: Y
authors.lastname: Yao
authors.forename: Hui-Ming
authors.initials: HM
authors.lastname: Hua
authors.forename: Yue-Hu
authors.initials: YH
authors.lastname: Pei
mesh_terms: D000731:Androstanes / Q000737:chemistry* / Q000302:isolation & purification; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D002725:Chloroform / Q000737:chemistry; D031105:Cynanchum / Q000737:chemistry*; D005960:Glucosides / Q000737:chemistry* / Q000302:isolation & purification; D006868:Hydrolysis; D009682:Magnetic Resonance Spectroscopy; D039821:Monoterpenes / Q000737:chemistry* / Q000302:isolation & purification; D009904:Optical Rotation; D018517:Plant Roots / Q000737:chemistry; D012997:Solvents; D016339:Spectrometry, Mass, Fast Atom Bombardment; D013055:Spectrophotometry, Infrared