title: Characterization of antibacterial nanoparticles from the scallop, Ptinopecten yessoensis.
abstract: To develop a new drug delivery system, antibacterial 50-900 nm nanoparticles of shell and internal organs from scallops collected off Huksan-Island, Korea, were prepared by dry grind technology respectively. The diameters, identities, and conformations of the scallop shell and internal organ particles were determined with a particle-size analyzer and by X-ray powder diffraction (XRD), scanning electron microscopy (SEM), and Raman spectroscopy. The antibacterial properties of the nanoparticles from scallop shell were investigated in the absence and the presence of scallop-shell extract. Bacterial growth was reduced with the supernatant of the nanoparticle scallop-shell extract. Also, the nanoparticles from scallop shell were much more effective as a skin softener than was powder. These facts provide us with guidelines for the study of the size-dependent properties of functional materials as well as for further applications to drug delivery systems (DDSs) and cosmetic raw materials.
authors.affiliation: Research Center for Advanced Science and Technology, Dongseo University, Busan 617-716, Korea.
authors.forename: Mi Suk
authors.initials: MS
authors.lastname: Jeong
authors.forename: Jeong Soon
authors.initials: JS
authors.lastname: Park
authors.forename: Seong Hwan
authors.initials: SH
authors.lastname: Song
authors.forename: Se Bok
authors.initials: SB
authors.lastname: Jang
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000633:toxicity*; D050296:Microbial Viability / Q000187:drug effects; D008855:Microscopy, Electron, Scanning; D053758:Nanoparticles / Q000737:chemistry* / Q000648:ultrastructure*; D010316:Particle Size; D049897:Pectinidae / Q000737:chemistry*; D013212:Staphylococcus epidermidis / Q000187:drug effects; D014961:X-Ray Diffraction