Synthesis of indanones via solid-supported [2+2+2] cyclotrimerization.
A new facile approach toward natural and unnatural indanones has been developed, featuring a solid-supported [2+2+2] cyclotrimerization as the key step. This strategy has been applied to the chemo- and regioselective assembly of indanone arrays and to the total synthesis of a recently isolated indanone marine natural product.
Senaiar
Ramesh S
RS
Department of Chemistry, North Carolina State University, Campus Box 8204, Raleigh, North Carolina 27695, USA.
Teske
Jesse A
JA
Young
Douglas D
DD
Deiters
Alexander
A