Large granular intestinal lymphosarcoma and leukemia in a dog.
A rare, large granular lymphocyte (LGL) tumor causing a protein-losing enteropathy and thrombocytopenia was diagnosed in an Irish wolfhound. The case had an aggressive clinical course, like most LGL tumors in humans. Immunophenotyping suggested that the LGL tumor in this dog was derived from a natural-killer cell.
Snead
Elisabeth C R
EC
Department of Small Animal Clinical Sciences, Western College of Veterinary Medicine, University of Saskatchewan, 52 Campus Drive, Saskatoon, Saskatchewan. liz.snead@usask.ca
D000818:Animals; D004283:Dog Diseases / Q000473:pathology*; D004285:Dogs; D017809:Fatal Outcome; D005260:Female; D016130:Immunophenotyping / Q000662:veterinary*; D007414:Intestinal Neoplasms / Q000473:pathology / Q000662:veterinary*; D007694:Killer Cells, Natural; D008228:Lymphoma, Non-Hodgkin / Q000473:pathology / Q000662:veterinary*