A new pyrone derivative from the endophytic fungus Penicillium paxilli PSU-A71.
One new pyrone derivative, named penicillone (1), together with paxilline, pyrenocines A (2) and B (3) were isolated from the endophytic fungus Penicillium paxilli PSU-A71. The structures were elucidated by spectroscopic methods. Pyrenocine B (3) mildly inhibited the growth of Microsporum gypseum SH-MU-4 with a MIC value of 32 microg/ml.
Rukachaisirikul
Vatcharin
V
Department of Chemistry, Faculty of Science, Prince of Songkla University, Songkla, Thailand. vatcharin.r@psu.ac.th
Kaeobamrung
Juthanat
J
Panwiriyarat
Wannarat
W
Saitai
Pimchanok
P
Sukpondma
Yaowapa
Y
Phongpaichit
Souwalak
S
Sakayaroj
Jariya
J
D000935:Antifungal Agents / Q000737:chemistry* / Q000302:isolation & purification; D002855:Chromatography, Thin Layer; D005285:Fermentation; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D008826:Microbial Sensitivity Tests; D008864:Microsporum / Q000187:drug effects / Q000254:growth & development; D010407:Penicillium / Q000737:chemistry*; D011753:Pyrones / Q000737:chemistry* / Q000302:isolation & purification