title: Fatal stroke in a young cocaine drug addict: chemical hair analysis and cervical artery examination twenty months after death.
abstract: We present a case of a 26-year-old female who died of acute cerebral infarction after thrombosis of the left internal carotid artery, conceivably related to cocaine use. The forensic examination was performed only twenty months post-mortem. Revaluation of clinical data was carried out after exhumation and forensic autopsy examination were done, including anatomic dissection of cervical vessels and histological and toxicological analyses. Interestingly, comparative histological examination of cervical arteries was more useful in determining the putative site of vascular damage than gross and histological examination of the brain itself, although the state of preservation of tissues was poor. In conclusion, when a vascular accident is suspected or has to be demonstrated, we suggest performing comparative histological examinations of selected artery samples, even several months after death.
authors.affiliation: Institute of Legal Medicine, Catholic University of the Sacred Heart, Largo Francesco Vito 1, 00168 Rome, Italy. fdegiorgio@tiscalinet.it
authors.forename: Fabio
authors.initials: F
authors.lastname: De Giorgio
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Vetrugno
authors.forename: Nadia
authors.initials: N
authors.lastname: Fucci
authors.forename: Juha
authors.initials: J
authors.lastname: Rainio
authors.forename: Tommaso
authors.initials: T
authors.lastname: Tartaglione
authors.forename: Vincenzo
authors.initials: V
authors.lastname: Di Lazzaro
authors.forename: Arnoldo
authors.initials: A
authors.lastname: Carbone
mesh_terms: D000328:Adult; D001158:Arteries / Q000737:chemistry; D001344:Autopsy; D001921:Brain / Q000000981:diagnostic imaging / Q000473:pathology; D002584:Cervix Uteri / Q000098:blood supply; D003042:Cocaine / Q000032:analysis*; D019970:Cocaine-Related Disorders / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology*; D017809:Fatal Outcome; D005260:Female; D006197:Hair / Q000737:chemistry*; D006801:Humans; D020521:Stroke; D014057:Tomography, X-Ray Computed
chemical_list: D003042:Cocaine