Control of chemoselectivity of microbial reaction with resin adsorbent: enhancement of Baeyer-Villiger oxidation over reduction.
Amberlite XAD-7, a hydrophobic polymer, was used to change microbial reaction of ketones from reduction to Baeyer-Villiger (BV) oxidation. Thus, D. magnusii NBRC 4600 and G. reessii NBRC 1112 could catalyze the BV reaction of ketones in the presence of the polymer while reduction of the substrates proceeded, and BV oxidation was scarcely found in the absence of the polymer.
Fujii
Mikio
M
School of Pharmaceutical Science, Toho University, 2-2-1 Miyama, Funabashi, Chiba, Japan. mfujii@phar.toho-u.ac.jp
Akita
Hiroyuki
H
Ida
Yoshiteru
Y
Nakagawa
Toshiya
T
Nakamura
Kaoru
K
D000180:Acrylic Resins / Q000737:chemistry*; D001203:Ascomycota / Q000737:chemistry*; D007659:Ketones / Q000737:chemistry*; D008956:Models, Chemical; D015394:Molecular Structure; D010084:Oxidation-Reduction; D011137:Polystyrenes / Q000737:chemistry*
D000180:Acrylic Resins; D007659:Ketones; D011137:Polystyrenes; C015661:amberlite XAD 7