[Surgical treatment for patients with gastric cancer: report of 2335 cases].
OBJECTIVE
To clarify the important factors affecting the prognosis of patient with gastric carcinoma.


METHODS
The data of 2335 cases of resected gastric carcinoma from Jan. 1996 to Dec. 2005 were studied by using univariate analysis and multivariate regression analysis.


RESULTS
Male patients accounted for 81.0% and female patients 19.0%. The ratio of male to female was 4.2: 1.0. Patients under 50 years old accounted for 77.2%. Two hundred and seventy-five cases were early gastric cancer, accounting for 11.8%, and another 2060 cases were advanced gastric cancer, accounting for 88.2%. Tumor diameter of 72.8% patients was more than 4 cm and 69.6% cases suffered with low differentiated cancer. Curative resections were performed in 1690 patients (72.4%) and palliative operation in other patients. After operation, 1538 cases (65.9%) received comprehensive treatment. For all cases, the 1-, 3- and 5-year survival rates were 71.9%, 45.3% and 40.1% respectively. The independent risk factors influencing prognosis of these patients were Borrmann classification,TNM staging, curative resection and multidisciplinary treatment through univariate and multivariate analyses.


CONCLUSIONS
The factors influencing prognosis of patient with gastric carcinoma after resection are Borrmann classification,TNM staging, curative resection and multidisciplinary treatment. Early and curative resection is the most important management to improve therapeutic efficacy of stomach cancer.
Chen
Lin
L
Department of General Surgery, General Hospital of PLA, Beijing 100853, China. chenlinbj@vip.sina.com
Zhang
Yong
Y
Wei
Bo
B
Zhao
Xiang-yang
XY
Li
Tao
T
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D011379:Prognosis; D012044:Regression Analysis; D013274:Stomach Neoplasms / Q000601:surgery*; D016896:Treatment Outcome; D055815:Young Adult