title: Give a dog a genome.
abstract: In 2004 the dog became only the fifth mammal to have its entire genome fully sequenced. The canine genome was sequenced in the hope that it would help scientists understand the complex evolutionary mechanisms that shape genes and genomes and provide a powerful tool for identifying genetic factors that contribute to human health and disease. It is expected that over the coming years the genome of man's best friend will help in the understanding of the genetic cause of many inherited diseases that humans and dogs have in common. Not only of obvious benefit to humans, these studies will enable the development of DNA diagnostic tests that breeders can use to identify which of their dogs carry mutations that put them at risk of developing particular conditions and thus, over time, eliminate those diseases from the breed.
authors.affiliation: Centre for Preventive Medicine, Animal Health Trust, Lanwades Park, Newmarket, Suffolk CB8 7UU, UK. cathryn.mellersh@aht.org.uk
authors.forename: Cathryn
authors.initials: C
authors.lastname: Mellersh
mesh_terms: D000818:Animals; D004283:Dog Diseases / Q000235:genetics; D004285:Dogs / Q000235:genetics*; D020022:Genetic Predisposition to Disease; D016678:Genome