title: Efficacy and problems associated with using a wet-wrap garment for children with severe atopic dermatitis.
abstract: Use of a wet wrap for short-term relief of itch in children with severe atopic dermatitis has been advocated but objective determination of its efficacy has been difficult and many issues associated with its use are yet to be defined. We tested a new garment for the wet-wrap procedure in six patients with atopic dermatitis and objectively determined whether a 3-day usage could indeed relieve the distressing symptom of itch using a wrist motion monitor. The garments were effective in the short-term improvement of itching, severity of atopic dermatitis and quality of life in these children. Many issues associated with its use were identified. Clear instructions and individualized regimes (such as the choice of emollient, bathing ointment and topical corticosteroid) are essential for optimal outcome.
authors.affiliation: Dermatology Research Centre, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong. ehon@cuhk.edu.hk
authors.forename: Kam-Lun Ellis
authors.initials: KL
authors.lastname: Hon
authors.forename: Kin-Yee
authors.initials: KY
authors.lastname: Wong
authors.forename: Lai-King
authors.initials: LK
authors.lastname: Cheung
authors.forename: Gladys
authors.initials: G
authors.lastname: Ha
authors.forename: Man-Ching Adrian
authors.initials: MC
authors.lastname: Lam
authors.forename: Ting-Fan
authors.initials: TF
authors.lastname: Leung
authors.forename: Chung-Mo
authors.initials: CM
authors.lastname: Chow
authors.forename: Yuk-Ming William
authors.initials: YM
authors.lastname: Tang
authors.forename: Nai-Ming Tommy
authors.initials: NM
authors.lastname: Luk
authors.forename: Alexander K C
authors.initials: AK
authors.lastname: Leung
mesh_terms: D000287:Administration, Topical; D000293:Adolescent; D001494:Baths / Q000379:methods*; D002648:Child; D002675:Child, Preschool; D003020:Clothing; D003876:Dermatitis, Atopic / Q000150:complications / Q000628:therapy*; D004643:Emollients / Q000008:administration & dosage; D005260:Female; D005938:Glucocorticoids / Q000008:administration & dosage; D006801:Humans; D008297:Male; D011537:Pruritus / Q000175:diagnosis / Q000209:etiology / Q000628:therapy*; D011788:Quality of Life; D012720:Severity of Illness Index
chemical_list: D004643:Emollients; D005938:Glucocorticoids