title: New biologically active epidioxysterols from Stereum hirsutum.
abstract: From the fungus Stereum hirsutum have been isolated and identified two new epidioxysterols 1, 4, together with two known ones 2 and 3. Their structures were elucidated on the basis of spectroscopic analysis and chemical reactions. Epidioxysterols 1-4 have been shown to possess a significant activity against Mycobacterium tuberculosis.
authors.affiliation: Department of Pharmaceutical Sciences, University of Trieste, Piazzale Europa 1, Trieste, Italy. cateni@units.it
authors.forename: Francesca
authors.initials: F
authors.lastname: Cateni
authors.forename: Bojan
authors.initials: B
authors.lastname: Doljak
authors.forename: Marina
authors.initials: M
authors.lastname: Zacchigna
authors.forename: Marko
authors.initials: M
authors.lastname: Anderluh
authors.forename: Andrej
authors.initials: A
authors.lastname: Piltaver
authors.forename: Giuditta
authors.initials: G
authors.lastname: Scialino
authors.forename: Elena
authors.initials: E
authors.lastname: Banfi
mesh_terms: D000995:Antitubercular Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D001487:Basidiomycota / Q000737:chemistry*; D002788:Cholesterol Esters / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D009169:Mycobacterium tuberculosis / Q000187:drug effects*
chemical_list: D000995:Antitubercular Agents; D002788:Cholesterol Esters; C421424:epidioxysterol