title: [Features of bronchial tuberculosis--an analysis of 103 cases].
abstract: OBJECTIVE
  The aim of this study is to clarify the features of bronchial tuberculosis.
  
  
  METHODS
  We analyzed the clinicopathological data from 103 out of 4467 (2.3%) cases of culture positive tuberculosis admitted to the National Hospital Organization Tokyo National Hospital in the period from 1993 to 2004 in which bronchial tuberculosis was confirmed by bronchofiberscopy.
  
  
  RESULTS
  There were 62 women and 41 men, and 53 cases were less than 50 years old. The most common symptom, namely cough was observed in 70 cases, while 79 cases showed III1 to III2 on roentgenographic examination, and 81 cases were smear-positive for acid-fast bacilli in the sputum. Regarding the bronchofiberscopic findings, ulcers were detected in 60 cases, and the major site of bronchial tuberculosis was in the left main bronchus (35 cases). The number of the cases in which the time span from the onset of symptoms to diagnosis took over 3 months was 29, and 26 of them were "doctor's delay" cases which had a history of medical consultation resulting in diagnosis and treatment of other diseases, such as bronchial asthma (7 cases). There were 41 cases in which the second bronchofiberscopic findings have been reviewed, and regardless of the length of the span from the onset to diagnosis, the first bronchofiberscopy mostly revealed ulcer within 1 month after the start of treatment for tuberculosis, and 3 months after the start of treatment, many patients developed fibrous scars. Between 1999 to 2004, the first bronchofiberscopies were usually performed within 2 weeks to 1 month after the start of the treatment in contrast to the cases admitted between 1993 to 1998 in which bronchofribroscopy was mainly performed before the start of the treatment. However, there were no differences in the findings due to the timing of bronchofiberscopy.
  
  
  CONCLUSIONS
  The clinical characteristics of bronchial tuberculosis have not changed, and the delay of diagnosis of bronchial tuberculosis due to doctor's delay also continues to be an important issue today. In patients showing positive sputum smear for mycobacteria, the timing of bronchofiberscopy, although required upon medical examination, is considered to be more appropriately performed from 2 weeks to 1 month after the start of treatment from the view point of nosocomial tuberculosis infection control strategy.
authors.affiliation: Department of Respiratory Diseases, National Hospital Organization Tokyo National Hospital, 3-1-1, Takeoka, Kiyose-shi, Tokyo 204-8585, Japan. tamura@tokyo.hosp.go.jp
authors.forename: Atsuhisa
authors.initials: A
authors.lastname: Tamura
authors.forename: Akira
authors.initials: A
authors.lastname: Hebisawa
authors.forename: Kimihiko
authors.initials: K
authors.lastname: Masuda
authors.forename: Masahiro
authors.initials: M
authors.lastname: Shimada
authors.forename: Makiko
authors.initials: M
authors.lastname: Kunogi
authors.forename: Yugo
authors.initials: Y
authors.lastname: Kaneko
authors.forename: Yoshinori
authors.initials: Y
authors.lastname: Matsui
authors.forename: Masahiro
authors.initials: M
authors.lastname: Kawashima
authors.forename: Junko
authors.initials: J
authors.lastname: Suzuki
authors.forename: Haruyuki
authors.initials: H
authors.lastname: Ariga
authors.forename: Nobuharu
authors.initials: N
authors.lastname: Ohshima
authors.forename: Hirotoshi
authors.initials: H
authors.lastname: Matsui
authors.forename: Hideaki
authors.initials: H
authors.lastname: Nagai
authors.forename: Shinobu
authors.initials: S
authors.lastname: Akagawa
authors.forename: Naohiro
authors.initials: N
authors.lastname: Nagayama
authors.forename: Yoshiko
authors.initials: Y
authors.lastname: Kawabe
authors.forename: Kazuko
authors.initials: K
authors.lastname: Machida
authors.forename: Atsuyuki
authors.initials: A
authors.lastname: Kurashima
authors.forename: Yutsuki
authors.initials: Y
authors.lastname: Nakajima
authors.forename: Hideki
authors.initials: H
authors.lastname: Yotsumoto
mesh_terms: D000328:Adult; D001982:Bronchial Diseases; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D014376:Tuberculosis