Drug discovery and development in the age of molecular medicine.
Drug discovery might be better termed drug invention. Discoveries take place globally, and many arise from academia and research institutes. The job of the biotechnology and pharmaceutical industry is to identify those that stand the greatest chance of being turned into medicines to improve health-in other words, to invent a practical outcome on the basis of discovery. In this commentary we identify some of the areas in which molecular medicine has had the greatest impact and continues to change the invention of medicines.
Vallance
P
P
Drug Discovery, GlaxoSmithKline, Greenford, Middlesex, UK. patrick.5.vallance@gsk.com
Levick
M
M
D000818:Animals; D015510:Clinical Medicine / Q000639:trends*; D015195:Drug Design; D004345:Drug Industry / Q000639:trends*; D005544:Forecasting; D023281:Genomics / Q000639:trends; D005838:Genotype; D006801:Humans; D008967:Molecular Biology / Q000639:trends*; D018579:Patient Selection; D010597:Pharmacogenetics / Q000639:trends*; D010599:Pharmacokinetics; D010601:Pharmacology, Clinical / Q000639:trends*; D010641:Phenotype; D015203:Reproducibility of Results