title: Simple anthropometric indices in relation to cardiovascular risk factors in Chinese type 2 diabetic patients.
abstract: To determine which is the best anthropometric index among body mass index (BMI), waist circumference (WC), waist to hip ratio (WHR) and waist to height ratio (WHtR) in type 2 diabetic patients, we examined the relationship between these indices and cardiovascular risk factors using partial correlation analysis, chi-square test, logistic regression analysis and Receiver Operator Characteristic (ROC) curves. Partial correlation analysis showed that among the 4 obesity indices, WHtR had the highest r values for all the cardiovascular risk factors in both sexes, followed by WC. Chi-square analysis which revealed that an increased WHtR was more strongly associated with hypertension, hypertriglyceridemia (high TG) and low high-density lipoprotein cholesterol (HDL-C) than the other indices. Logistic regression analysis showed that, after controlling for age, the hypertension, high TG and low HDL-C odds ratios of WHtR > or = 0.5 were 2.56 (95% CI: 1.24, 5.29), 2.87 (95% CI: 1.43, 5.78), 2.59 (95% CI: 1.03, 6.59) in men and 3.75 (95% CI: 1.75, 8.05), 3.21 (95% CI: 1.52, 6.79), 3.62 (95% CI: 1.43, 9.21) in women, respectively. In ROC analysis, the areas under curve of WHtR were the largest for at least one risk factor in both men and women. These results indicated that WHtR had a higher correlation with cardiovascular risk factors than WC, WHR or BMI in newly diagnosed type 2 diabetes. We proposed the measurement of WHtR as a screening tool for cardiovascular risk factors in this population.
authors.affiliation: Department of Endocrinology, Union Hospital, Tongji Medical School, Huazhong Technology University, Wuhan 430022, Hubei, PR China. hongyzn_wu2003@yahoo.com.cn
authors.forename: Hong-Yan
authors.initials: HY
authors.lastname: Wu
authors.forename: Lu-Lu
authors.initials: LL
authors.lastname: Chen
authors.forename: Juan
authors.initials: J
authors.lastname: Zheng
authors.forename: Yun-Fei
authors.initials: YF
authors.lastname: Liao
authors.forename: Min
authors.initials: M
authors.lastname: Zhou
mesh_terms: D000886:Anthropometry; D001827:Body Height; D015992:Body Mass Index; D002318:Cardiovascular Diseases / Q000453:epidemiology* / Q000208:ethnology / Q000473:pathology; D016009:Chi-Square Distribution; D002681:China; D003924:Diabetes Mellitus, Type 2 / Q000150:complications* / Q000208:ethnology / Q000473:pathology*; D005260:Female; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000150:complications / Q000208:ethnology / Q000473:pathology; D018570:Risk Assessment; D012307:Risk Factors; D049629:Waist-Hip Ratio