title: [Transient osteoporosis of the hip in pregnancy. Successful treatment with calcitonin: a case report].
abstract: Transient osteoporosis of the hip is a rare clinical disorder of unknown etiology, characterized by hip pain and functional disability that resolves spontaneously in 6-24 months. Despite a benign prognosis, the long clinical course causes prolonged disability. We report on a case of transient osteoporosis of the hip during pregnancy that was rapidly resolved with the use of calcitonin. An accurate diagnosis was made 2 months after the onset of symptoms (4 weeks postpartum) based on findings in the form of bone marrow edema of the right hip by magnetic resonance imaging. The patient received calcitonin for 8 weeks and the beneficial effect was observed after 3 weeks of therapy with full resolution of symptoms after 8 weeks of therapy (4 months after onset of symptoms). We suggest that the use of calcitonin may be considered as a therapeutic intervention to shorten the disease duration.
authors.affiliation: University Department of Rheumatology, Zagreb University Hospital Center, Kispaticeva 12, 10000 Zagreb, Kroatien. nadica_laktasic@yahoo.com
authors.forename: N
authors.initials: N
authors.lastname: Laktasic-Zerjavic
authors.forename: B
authors.initials: B
authors.lastname: Curkovic
authors.forename: D
authors.initials: D
authors.lastname: Babic-Naglic
authors.forename: K
authors.initials: K
authors.lastname: Potocki
authors.forename: M
authors.initials: M
authors.lastname: Prutki
authors.forename: D
authors.initials: D
authors.lastname: Soldo-Juresa
mesh_terms: D000328:Adult; D050071:Bone Density Conservation Agents / Q000627:therapeutic use*; D002116:Calcitonin / Q000627:therapeutic use*; D002118:Calcium / Q000627:therapeutic use; D002762:Cholecalciferol / Q000627:therapeutic use; D004164:Diphosphonates; D004359:Drug Therapy, Combination; D005260:Female; D006621:Hip Joint / Q000187:drug effects / Q000473:pathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D015609:Organotechnetium Compounds; D010024:Osteoporosis / Q000175:diagnosis / Q000188:drug therapy*; D011247:Pregnancy; D011248:Pregnancy Complications / Q000175:diagnosis / Q000188:drug therapy*; D011263:Pregnancy Trimester, Third; D011644:Puerperal Disorders / Q000175:diagnosis / Q000188:drug therapy; D011877:Radionuclide Imaging
chemical_list: D050071:Bone Density Conservation Agents; D004164:Diphosphonates; D015609:Organotechnetium Compounds; C033905:technetium Tc 99m 1,1-diphosphonopropane-2,3-dicarboxylic acid; D002762:Cholecalciferol; C028815:salmon calcitonin; D002116:Calcitonin; D002118:Calcium