Serum brain-derived neurotrophic factor levels in conversion disorder: Comparative study with depression.
The aim of the present study was to compare serum brain-derived neurotrophic factor (BDNF) levels of patients with major depressive disorder (MDD) and conversion disorder (CD). Serum BDNF levels were measured in the following three groups: 15 CD patients without any comorbid diagnosis of psychiatric disorder, 24 patients with MDD, and 26 healthy subjects without any psychiatric diagnosis or psychiatric treatment. The serum BDNF level of the healthy control group (31.4 +/- 8.8 ng/mL) was statistically higher than the level of the MDD group (21.2 +/- 11.3 ng/mL) and the CD group (24.3 +/- 9.0 ng/mL; P = 0.008). This suggests that BDNF level may play a similar role in the pathophysiology of MDD and CD.
Deveci
Artuner
A
Department of Psychiatry, Celal Bayar University School of Medicine, Manisa, Turkey. artuner.d@superonline.com
Aydemir
Omer
O
Taskin
Oryal
O
Taneli
Fatma
F
Esen-Danaci
Aysen
A
D000293:Adolescent; D000328:Adult; D015415:Biomarkers / Q000097:blood; D019208:Brain-Derived Neurotrophic Factor / Q000097:blood*; D003291:Conversion Disorder / Q000097:blood* / Q000523:psychology; D003865:Major Depressive Disorder / Q000097:blood* / Q000523:psychology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010555:Personality Inventory; D012016:Reference Values; D013315:Stress, Psychological / Q000097:blood / Q000150:complications
D015415:Biomarkers; D019208:Brain-Derived Neurotrophic Factor