Synthesis, spectroscopic and biological aspects of iron(II) complexes.
Five novel coordinated complexes of iron(II) with ciprofloxacin and neutral bidentate ligands have been prepared and characterized using elemental analyses, magnetic measurements, IR spectra, UV-VIS spectral, thermogravimetric analyses, 1H-NMR and 13C-NMR. The antimicrobial activity of the individual ligands, metal salt and metal complexes with respect to Bacillus subtilis, Escherichia coli, Bacillus cereus, Staphylococcus aureus, Salmonella typhi, Serratia marcescens, Aspergillus niger, Aspergillus flavus and Lasiodiplodia theobromae were evaluated by the agar-plate technique in comparison to reference standard drugs (ofloxacin, levofloxacin and fluconozole). Binding of the complexes to DNA was studied and is discussed.
Pansuriya
Pramod B
PB
Department of Chemistry-Sardar Patel University, Vallabh Vidyanagar, 388 120 Gujarat, India.
Dhandhukia
Pinakin
P
Thakkar
Vasudev
V
Patel
Mohan N
MN
D000890:Anti-Infective Agents / Q000494:pharmacology; D001230:Aspergillus / Q000378:metabolism; D001409:Bacillus cereus / Q000378:metabolism; D001412:Bacillus subtilis / Q000378:metabolism; D004926:Escherichia coli / Q000378:metabolism; D007501:Iron / Q000737:chemistry*; D058085:Iron Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D008956:Models, Chemical; D012485:Salmonella typhi / Q000378:metabolism; D012706:Serratia marcescens / Q000378:metabolism; D013055:Spectrophotometry, Infrared / Q000379:methods*; D013056:Spectrophotometry, Ultraviolet / Q000379:methods*; D013211:Staphylococcus aureus / Q000378:metabolism
D000890:Anti-Infective Agents; D058085:Iron Compounds; D007501:Iron