[Transfusion-related acute lung injury. A case report].
A transfusion-related acute lung injury (Trali) is a noncardiogenic lung oedema occurring within six hours following the infusion of a blood component. It is a under-recognized transfusional accident, for which the aetiology and physiopathology are still controversial, evoking immunological or nonimmunological mechanisms which do not seem sufficient per se to cause this accident. A predisposing condition, associated with leucostasis in pulmonary vessels, is required. The pulmonary lesion is due to the activation of neutrophils in contact with endothelial cells of lung micro-capillary vessels. We report a case of Trali following the transfusion of the first red blood cells unit to a 26-year-old young woman.
Laoutid
J
J
Service de réanimation chirurgicale, hôpital militaire d'instruction Mohammed-V, Rabat, Maroc.
Baite
A
A
Atmani
M
M
Safi
L
L
Atmani
M
M
D000208:Acute Disease; D000328:Adult; D002585:Cesarean Section; D005260:Female; D006801:Humans; D008171:Lung Diseases / Q000209:etiology*; D055370:Lung Injury; D011247:Pregnancy; D012128:Respiratory Distress Syndrome / Q000209:etiology; D065227:Transfusion Reaction