title: A single-chip signal processing and telemetry engine for an implantable 96-channel neural data acquisition system.
abstract: A fully implantable neural data acquisition system is a key component of a clinically viable cortical brain-machine interface. We present the design and implementation of a single-chip device that serves the processing needs of such a system. Our device processes 96 channels of multi-unit neural data and performs all digital processing necessary for bidirectional wireless communication. The implementation utilizes a single programmable logic device that is responsible for performing data reduction on the 96 channels of neural data, providing a bidirectional telemetry interface to a transceiver and performing command interpretation and system supervision. The device takes as input neural data sampled at 31.25 kHz and outputs a line-encoded serial bitstream containing the information to be transmitted by the transceiver. Data can be output in one of the following four modes: (1) streaming uncompressed data from a single channel, (2) extracted spike waveforms from any subset of the 96 channels, (3) 1 ms bincounts for each channel or (4) streaming data along with extracted spikes from a single channel. The device can output up to 2000 extracted spikes per second with latencies suitable for a brain-machine interface application. This device provides all of the digital processing components required by a fully implantable system.
authors.affiliation: Department of Biomedical Engineering, Duke University, Durham, NC 27708, USA. mr38@duke.edu
authors.forename: Michael
authors.initials: M
authors.lastname: Rizk
authors.forename: Iyad
authors.initials: I
authors.lastname: Obeid
authors.forename: Stephen H
authors.initials: SH
authors.lastname: Callender
authors.forename: Patrick D
authors.initials: PD
authors.lastname: Wolf
mesh_terms: D000818:Animals; D001921:Brain / Q000502:physiology*; D004567:Electrodes, Implanted; D004569:Electroencephalography / Q000295:instrumentation*; D004867:Equipment Design; D019544:Equipment Failure Analysis; D006801:Humans; D012815:Signal Processing, Computer-Assisted / Q000295:instrumentation*; D018511:Systems Integration; D013686:Telemetry / Q000295:instrumentation*