Wilms' tumour in adults: a case report and review of the literature.
BACKGROUND
Wilms' tumour is a very rare adult malignancy representing 1% of adult renal tumours. It is however the most common renal tumour of childhood, and adult patients are treated in accordance with paediatric protocols.


OBJECTIVE
To review modern day management of adult Wilms' tumour.


METHODS
We report a case of adult Wilms' tumour and discuss the management including the use of newer treatment modalities.


RESULTS
Following diagnostic nephrectomy, our patient was treated with chemotherapy in accordance with North American paediatric protocols and PET scanning was used to diagnose early relapse.


CONCLUSIONS
In the absence of randomised controlled data, central reporting of cases of adult Wilms' Tumour may help improve management. The incorporation of newer chemotherapeutic agents, high-dose therapy and PET scanning into treatment protocols should improve outcome for these patients.
Gallagher
D J
DJ
Department of Medical Oncology, Mater Misercordiae University Hospital, Eccles St, Dublin 7, Ireland. Daithig@gmail.com
Duffy
A
A
McCaffrey
J
J
D000328:Adult; D000970:Antineoplastic Agents / Q000008:administration & dosage* / Q000627:therapeutic use; D016190:Carboplatin / Q000627:therapeutic use; D003520:Cyclophosphamide / Q000627:therapeutic use; D005047:Etoposide / Q000627:therapeutic use; D006801:Humans; D008297:Male; D009392:Nephrectomy; D049268:Positron-Emission Tomography; D009396:Wilms Tumor / Q000175:diagnosis* / Q000188:drug therapy / Q000601:surgery
D000970:Antineoplastic Agents; D005047:Etoposide; D003520:Cyclophosphamide; D016190:Carboplatin