Mechanisms and effects of green tea on cardiovascular health.
Green tea, rich in antioxidant and anti-inflammatory catechins, especially epigallocatechin gallate (EGCG), has been shown to reduce surrogate markers of atherosclerosis and lipid peroxidation, particularly LDL oxidation and malondialdehyde concentrations, in several in vitro, animal, and limited clinical studies. Epidemiological observations in Southeast Asian countries indicate an inverse correlation exists between habitual consumption of green tea beverages and the incidence of cardiovascular events. A few short-term clinical studies have reported its effects in attenuating biomarkers of oxidative stress and inflammation among smokers, and an ability to decrease postprandial lipemia in hypercholesterolemic subjects has also been suggested. However, further investigations are needed to confirm the potential role of green tea beverages and the safety of green tea supplements in reducing body fat, as well as other biomarkers of cardiovascular disease risks.
Basu
Arpita
A
Department of Nutritional Sciences, 301 Human Environmental Sciences, Oklahoma State University, Stillwater, OK 74078-6141, USA. arpita.basu@okstate.edu
Lucas
Edralin A
EA
D000975:Antioxidants / Q000008:administration & dosage / Q000493:pharmacokinetics*; D001628:Beverages; D001682:Biological Availability; D002318:Cardiovascular Diseases / Q000453:epidemiology* / Q000517:prevention & control; D002392:Catechin / Q000008:administration & dosage / Q000493:pharmacokinetics*; D005419:Flavonoids / Q000008:administration & dosage / Q000493:pharmacokinetics*; D006801:Humans; D015227:Lipid Peroxidation / Q000187:drug effects; D010636:Phenols / Q000008:administration & dosage / Q000493:pharmacokinetics*; D059808:Polyphenols; D012307:Risk Factors; D012907:Smoking; D013662:Tea / Q000737:chemistry; D015431:Weight Loss
D000975:Antioxidants; D005419:Flavonoids; D010636:Phenols; D059808:Polyphenols; D013662:Tea; D002392:Catechin