[Study of cardiopulmonary adaptation during exercise in patients after extracardiac conduit total cavopulmonary connection].
OBJECTIVE
To study cardiopulmonary physiology during exercise in patients after extracardiac total cavopulmonary connection (ECTCPC).


METHODS
Twenty-six patients were studied after ECTCPC by exercise testing with bicycle treadmill protocol. Heart rate (HR), blood pressure (BP), respiratory frequency (RF) and pulse oxygen saturation (SpO(2)) were measured continuously; twenty-six patients suffered from Fallot 4 underwent biventricular repair were also studied as control group.


RESULTS
In ECTCPC group, HR, BP, SpO(2) and RF all increased with exercise below 3 grade; when exceed 4 grade, BP, SpO(2) decreased and RF kept increasing. Compared with control group, HR, RF were higher (t = 2.13, P < 0.05; t = 2.31, P < 0.05), SpO(2) was lower (t = 2.46, P < 0.05) under the quiescent condition; When exceed 3 grade, HR, BP, SpO(2) decreased more significantly, but RF increased continuously. In fenestration group after ECTCPC, HR reached the top at 5 grades, but in group without fenestration it reached the top at 3 grades; In the whole process of exercising, RF kept higher and SpO(2) kept lower in fenestration group.


CONCLUSIONS
The ECTCPC patients showed obviously exercise limitation. Totally bypass of sinoatrial node in this operation may have some adverse effects on the integer regulation of HR.
Yin
Zong-tao
ZT
Department of Cardiovascular Surgery, the General Hospital of Shenyang Military Command, Shenyang 110016, China. yzt1210@hotmail.com.
Zhu
Hong-yu
HY
Wang
Zeng-wei
ZW
Zhang
Ren-fu
RF
Zhang
Nan-bin
NB
Fang
Min-hua
MH
Song
Heng-chang
HC
D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D005080:Exercise Test; D005260:Female; D005500:Follow-Up Studies; D018729:Fontan Procedure / Q000379:methods*; D006330:Heart Defects, Congenital / Q000503:physiopathology* / Q000601:surgery; D006801:Humans; D008297:Male; D010807:Physical Endurance / Q000502:physiology*; D011184:Postoperative Period