[Experimental approaches to study in vivo angiogenesis].
Angiogenesis has become a major issue in oncology. Different in vivo angiogenesis assays have been developed in order to better understand fundamental aspects of vascular development or to investigate the effect of therapeutic molecules on blood vessel growth. In this article, we will briefly review the main in vivo angiogenesis assays relevant to oncology and discuss their advantages and disadvantages.
Kilarski
Witold
W
Inserm E113, Laboratoire des Mécanismes moléculaires de l'angiogenèse, Université Bordeaux I, avenue des Facultés, 33405 Talence.
Bikfalvi
Andreas
A
D000818:Animals; D001808:Blood Vessels / Q000196:embryology; D002642:Chick Embryo; D049033:Chorioallantoic Membrane / Q000098:blood supply; D003094:Collagen; D016510:Corneal Neovascularization / Q000209:etiology; D004338:Drug Combinations; D004431:Ear, External / Q000098:blood supply; D007797:Laminin; D023421:Models, Animal; D009369:Neoplasms / Q000098:blood supply; D009389:Neovascularization, Pathologic / Q000175:diagnosis / Q000196:embryology*; D018919:Neovascularization, Physiologic / Q000502:physiology*; D011509:Proteoglycans; D011817:Rabbits
D004338:Drug Combinations; D007797:Laminin; D011509:Proteoglycans; C059485:matrigel; D003094:Collagen