title: Chemical composition and antimicrobial activity of the essential oil of Algerian Phlomis bovei De Noé subsp. bovei.
abstract: The chemical composition of essential oil obtained by steam distillation of dried aerial parts of Phlomis bovei De Noé subsp. bovei collected from Algeria, was analyzed by GC and GC/MS. Seventy five constituents (corresponding to 86.37% of the total weight) were identified. The main components were: germacrene D, beta-caryophyllene, beta-bournonene, thymol and hexahydrofarnesyl acetone. Furthermore, the antimicrobial activity of the oil was evaluated against six gram (+/-) bacteria and three pathogenic fungi, using the agar dilution technique. It was found that the oil exhibited strong antimicrobial activity against most of the tested microorganisms.
authors.affiliation: Department of Pharmacy, Div. of Pharmacognosy, Chemistry of Natural Products, University of Athens, Panepistimiopolis Zografou, 15771 Athens, Greece. liolios@pharm.uoa.gr
authors.forename: Christos
authors.initials: C
authors.lastname: Liolios
authors.forename: Hocine
authors.initials: H
authors.lastname: Laouer
authors.forename: Nacira
authors.initials: N
authors.lastname: Boulaacheb
authors.forename: Olga
authors.initials: O
authors.lastname: Gortzi
authors.forename: Ioanna
authors.initials: I
authors.lastname: Chinou
mesh_terms: D000096:Acetone / Q000737:chemistry; D000890:Anti-Infective Agents / Q000737:chemistry / Q000494:pharmacology*; D002626:Chemistry, Pharmaceutical / Q000379:methods; D002849:Chromatography, Gas / Q000379:methods; D004353:Drug Evaluation, Preclinical; D006090:Gram-Negative Bacteria / Q000378:metabolism; D006094:Gram-Positive Bacteria / Q000378:metabolism; D013058:Mass Spectrometry / Q000379:methods; D008956:Models, Chemical; D009822:Oils, Volatile / Q000737:chemistry*; D031345:Phlomis / Q000378:metabolism; D010936:Plant Extracts / Q000378:metabolism*; D010938:Plant Oils / Q000737:chemistry*; D013943:Thymol / Q000737:chemistry
chemical_list: D000890:Anti-Infective Agents; D009822:Oils, Volatile; D010936:Plant Extracts; D010938:Plant Oils; D000096:Acetone; D013943:Thymol