title: A triazole-templated ring-closing metathesis for constructing novel fused and bridged triazoles.
abstract: The feasibility of trapping the vinyl copper intermediate generated in situ from azide-[3 + 2] cycloadditions and viability of employing these triazoles as unique templates for ring-closing metathesis are described here; this work effectively combines the two powerful reactions for the first time to construct various de novo fused and bridged triazoles that are otherwise not trivial to synthesize.
authors.affiliation: Division of Pharmaceutical Sciences and Department of Chemistry, 777 Highland Avenue, University of Wisconsin, Madison, WI 53705-2222, USA.
authors.forename: Xuejun
authors.initials: X
authors.lastname: Zhang
authors.forename: Richard P
authors.initials: RP
authors.lastname: Hsung
authors.forename: Hongyan
authors.initials: H
authors.lastname: Li
mesh_terms: D003500:Cyclization; D014230:Triazoles / Q000737:chemistry*
chemical_list: D014230:Triazoles