title: Finite element modeling of the thoracic aorta: including aortic root motion to evaluate the risk of aortic dissection.
abstract: OBJECTIVE
  We propose that the aortic root motion plays an important role in aortic dissection.
  
  
  RESULTS
  A finite element model of the aortic root, arch and branches of the arch was built to assess the influence of aortic root displacement and pressure on the aortic wall stress. The largest stress increase due to aortic root displacement was found at approximately 2 cm above the top of the aortic valve. There, the longitudinal stress increased by 50% to 0.32 MPa when 8.9 mm axial displacement was applied in addition to 120 mmHg luminal pressure. A similar result was observed when the pressure load was increased to 180 mmHg without axial displacement.
  
  
  CONCLUSIONS
  Both aortic root displacement and hypertension significantly increase the longitudinal stress in the ascending aorta, which could play a decisive role in the development of various aortic pathologies, including aortic dissection.
authors.affiliation: Department of Cardiac Surgery, University Hospital Heidelberg, INF 326, 69120, Heidelberg, Germany. carsten.beller@urz.uni-heidelberg.de
authors.forename: C J
authors.initials: CJ
authors.lastname: Beller
authors.forename: M R
authors.initials: MR
authors.lastname: Labrosse
authors.forename: M J
authors.initials: MJ
authors.lastname: Thubrikar
authors.forename: F
authors.initials: F
authors.lastname: Robicsek
mesh_terms: D000784:Aortic Dissection / Q000503:physiopathology*; D001013:Aorta, Thoracic / Q000503:physiopathology*; D001014:Aortic Aneurysm / Q000503:physiopathology*; D001783:Blood Flow Velocity; D001794:Blood Pressure; D003198:Computer Simulation; D004548:Elasticity; D020342:Finite Element Analysis; D006801:Humans; D008955:Models, Cardiovascular; D009068:Movement; D018570:Risk Assessment / Q000379:methods*; D012307:Risk Factors; D033081:Shear Strength; D013314:Stress, Mechanical