title: Palliative surgery for rectal cancer in a national cohort.
abstract: OBJECTIVE
  Whether resection of the primary tumour is of benefit to patients with incurable rectal cancer (RC) remains a matter of debate. In this study we analyse prospectively recorded data from a national cohort.
  
  
  METHODS
  Among 4831 patients diagnosed with RC between 1997 and 2001, 838 (17%) patients were treated with palliative surgery. Patients were stratified according to disease stage, age and type of surgery.
  
  
  RESULTS
  A significantly longer median survival, 12 (range 10-13) months, was observed in patients treated with resection of the primary tumour compared with 5 (range 4-6) months in patients treated with nonresective procedures (P < 0.001). Median survival in months was significantly (P < 0.001) related to age (13; < 60 years of age, 10; 60 to 69 years, 7; 70 to 79 years, 6; >/= 80 years of age). In patients over 80 years, survival was similar regardless of the treatment. Thirty-day mortality varied from 2.5% to 20%, according to age groups.
  
  
  CONCLUSIONS
  The longer survival observed in patients with resection of the primary tumour may partly be explained by patient selection. Elderly patients (>/= 80 years) had a similar survival, irrespective of resection of the primary tumour or not. Careful consideration of the individual patient, extent of disease and treatment-related factors are important in decision-taking for palliative treatment for patients with advanced RC.
authors.affiliation: Department of Surgery, Stavanger University Hospital, Stavanger, Norway.
authors.forename: H K
authors.initials: HK
authors.lastname: Sigurdsson
authors.forename: H
authors.initials: H
authors.lastname: Kørner
authors.forename: O
authors.initials: O
authors.lastname: Dahl
authors.forename: A
authors.initials: A
authors.lastname: Skarstein
authors.forename: J A
authors.initials: JA
authors.lastname: Søreide
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D015331:Cohort Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D009664:Norway; D010166:Palliative Care; D011446:Prospective Studies; D012004:Rectal Neoplasms / Q000473:pathology* / Q000601:surgery*; D012042:Registries; D016019:Survival Analysis; D016896:Treatment Outcome