title: Drug rash with eosinophilia and systemic symptoms (DRESS) syndrome: suspected association with titanium bioprosthesis.
abstract: Drug rash with eosinophilia and systemic symptoms (DRESS), also known as hypersensitivity syndrome, is an idiosyncratic drug reaction presenting with fever, diffuse lymphadenopathy, exfoliative dermatitis, and visceral involvement, which may include hepatitis, pneumonitis, pericarditis, myocarditis, nephritis, and colitis. This report describes a 19-year-old, previously healthy man with manifestations of hypersensitivity (DRESS) syndrome after acquiring a titanium bioprosthesis for a spinal fracture. To our knowledge, there have been no prior reports of DRESS syndrome in association with titanium bioprosthetic implants.
authors.affiliation: Veterans Affairs Medical Center and Department of Medicine, University of Tennessee Health Science Center, Memphis, Tennessee, USA.
authors.forename: Fareha
authors.initials: F
authors.lastname: Nawaz
authors.forename: Barry M
authors.initials: BM
authors.lastname: Wall
mesh_terms: D000328:Adult; D001705:Bioprosthesis / Q000009:adverse effects*; D003875:Drug Eruptions; D004342:Drug Hypersensitivity / Q000175:diagnosis*; D006801:Humans; D006968:Hypersensitivity, Delayed / Q000139:chemically induced*; D007668:Kidney / Q000000981:diagnostic imaging / Q000187:drug effects / Q000473:pathology; D008297:Male; D016103:Spinal Fractures / Q000628:therapy; D013577:Syndrome; D014025:Titanium / Q000009:adverse effects*; D014057:Tomography, X-Ray Computed
chemical_list: D014025:Titanium