Resolution of retinoschisis after vitreous surgery in X-linked retinoschisis.
OBJECTIVE
To describe the efficacy of vitreous surgery to treat X-linked retinoschisis.


METHODS
Retrospective, comparative, interventional case series.


METHODS
Three patients (5 eyes) had foveal retinoschisis with peripheral retinoschisis. The patients' ages were 26, 7, and 17 years at the first surgery. The preoperative best-corrected visual acuity (BCVA) was 20/100 and 20/40 in patient 1, 20/30 in patient 2, and 20/100 and 20/200 in patient 3.


METHODS
The vitreous surgery consisted of core vitrectomy, surgically induced posterior vitreous detachment (PVD), removal of the internal limiting membrane (except for the right eye of patient 1), and 30% sulfur hexafluoride gas tamponade. The follow-up periods ranged from 6 months to 12 years.


METHODS
Best-corrected visual acuity and retinal tomography monitored by optical coherence tomography.


RESULTS
Restoration of the foveal depression with collapse of the schisis cavity was achieved with the first surgery in 4 (80%) of the 5 eyes. In the right eye of patient 1, the retinoschisis persisted after the first surgery because of failed surgically induced PVD; the retinoschisis resolved promptly after the second surgery with successful induction of PVD. The BCVA improved in 3 eyes and was unchanged in 2 eyes.


CONCLUSIONS
Vitreous surgery resulted in reattachment of the retinoschisis with visual improvement. Vitreous traction may play a role in the development of foveal retinoschisis.
Ikeda
Fumiko
F
Department of Ophthalmology, Gunma University School of Medicine, Maebashi, Japan.
Iida
Tomohiro
T
Kishi
Shoji
S
D000293:Adolescent; D000328:Adult; D002648:Child; D040181:Genetic Diseases, X-Linked / Q000175:diagnosis / Q000503:physiopathology / Q000601:surgery*; D006801:Humans; D008297:Male; D011184:Postoperative Period; D041441:Retinoschisis / Q000175:diagnosis / Q000235:genetics* / Q000503:physiopathology / Q000601:surgery*; D012189:Retrospective Studies; D041623:Tomography, Optical Coherence; D016896:Treatment Outcome; D014792:Visual Acuity; D014821:Vitrectomy