Caught in the act: an ABC transporter on the move.
The latest structure of the vitamin B12 permease reported in Science by Hvorup and colleagues represents an unexpected, asymmetric state of an ABC transporter, and indicates that the translocation cycle may be even more complex than previously thought (Hvorup et al., 2007).
Parcej
David
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Tampé
Robert
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D018528:ATP-Binding Cassette Transporters / Q000737:chemistry / Q000378:metabolism / Q000502:physiology*; D011487:Protein Conformation; D021381:Protein Transport; D014805:Vitamin B 12 / Q000378:metabolism
D018528:ATP-Binding Cassette Transporters; D014805:Vitamin B 12