title: Whipple's disease in mentally retarded patients: report of two cases.
abstract: Of 21 patients diagnosed with Whipple's disease (WD) by polymerase chain reaction (PCR), 3 were mentally retarded. We describe 2 of these patients, both of whom had WD in the central nervous system. WD was confirmed with PCR on blood and, for 1 patient, also on cerebrospinal fluid (CSF).
authors.affiliation: Department of Medical Microbiology and Infection Control, VU University Medical Centre, Amsterdam, The Netherlands. a.pettersson@vumc.nl
authors.forename: Annika
authors.initials: A
authors.lastname: Pettersson
authors.forename: Lisa
authors.initials: L
authors.lastname: van Winsen
authors.forename: Bob
authors.initials: B
authors.lastname: van Oosten
authors.forename: Cornelis
authors.initials: C
authors.lastname: Kramers
authors.forename: Andre
authors.initials: A
authors.lastname: van de Ven
authors.forename: Paul
authors.initials: P
authors.lastname: Savelkoul
authors.forename: Michiel
authors.initials: M
authors.lastname: van Agtmael
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008607:Intellectual Disability / Q000150:complications*; D016133:Polymerase Chain Reaction; D008061:Whipple Disease / Q000097:blood / Q000134:cerebrospinal fluid / Q000175:diagnosis* / Q000188:drug therapy
chemical_list: D000900:Anti-Bacterial Agents