Concomitant use of ibuprofen and aspirin.
Last September, the U.S. Food and Drug Administration (FDA) Center for Drug Evaluation and Research (CDER) published the following notice for consumers and healthcare professionals cautioning about the interference with the antiplatelet effects of low dose aspirin that can occur when aspirin is taken concomitantly with ibuprofen.
D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage / Q000494:pharmacology*; D001241:Aspirin / Q000008:administration & dosage / Q000494:pharmacology*; D002316:Cardiotonic Agents / Q000008:administration & dosage / Q000494:pharmacology*; D004347:Drug Interactions; D004359:Drug Therapy, Combination; D006801:Humans; D007052:Ibuprofen / Q000008:administration & dosage / Q000494:pharmacology*; D010975:Platelet Aggregation Inhibitors / Q000008:administration & dosage / Q000494:pharmacology*
D000894:Anti-Inflammatory Agents, Non-Steroidal; D002316:Cardiotonic Agents; D010975:Platelet Aggregation Inhibitors; D001241:Aspirin; D007052:Ibuprofen