A case of meningoencephalitis associated with G1P[8] rotavirus infection in a Japanese child.
We report the case of a 2-y, 11-month-old boy with G1P[8] rotavirus infection accompanied by acute meningoencephalitis. Substitutions in both the VP4 and VP7 genes were found in the identified strain. A commonly circulating G1P[8] rotavirus with such mutations might be associated with the pathogenesis of CNS complications, including meningoencephalitis.
Goto
Tamako
T
Department of Pediatrics, Jichi Medical School, Yakushiji, Shimotsuke, Japan.
Kimura
Hirokazu
H
Numazaki
Kei
K
Akiyama
Miho
M
Kato
Masahiko
M
Noda
Masahiro
M
Nozaki
Yasuyuki
Y
Tanaka-Taya
Keiko
K
Taniguchi
Kiyosu
K
Yamagata
Takanori
T
Nishio
Osamu
O
Oogane
Teruko
T
Momoi
Mariko Y
MY
Okabe
Nobuhiko
N
D000212:Acyclovir / Q000627:therapeutic use; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000956:Antigens, Viral / Q000235:genetics; D000998:Antiviral Agents / Q000627:therapeutic use; D044466:Asian People; D036022:Capsid Proteins / Q000235:genetics; D002228:Carbenicillin / Q000627:therapeutic use; D002675:Child, Preschool; D005990:Glycerol / Q000627:therapeutic use; D006801:Humans; D007564:Japan / Q000208:ethnology; D008297:Male; D008587:Meningitis, Viral / Q000175:diagnosis / Q000821:virology*; D010802:Phylogeny; D012401:Rotavirus / Q000145:classification* / Q000235:genetics*; D012400:Rotavirus Infections / Q000821:virology*
D000900:Anti-Bacterial Agents; D000956:Antigens, Viral; D000998:Antiviral Agents; D036022:Capsid Proteins; C060339:VP4 protein, Rotavirus; C050779:VP7 protein, Rotavirus; D002228:Carbenicillin; D005990:Glycerol; D000212:Acyclovir