title: [Clinical observation on acupuncture at the five-zangshu for treatment of perimenopausal syndrome].
abstract: OBJECTIVE
  To observe therapeutic effect and safety of acupuncture at the five-zangshu for treatment of perimenopausal syndrome (PMS).
  
  
  METHODS
  Forty cases of PMS were randomly divided into a treatment group and a control group, 20 cases in each group. The treatment group were treated with acupuncture at the five-zangshu and the control group with oral administration of Premarin tablets. The therapeutic effects and changes of Kupperman scores, and serum estradiol (E2), follicle stimulating hormone (FSH), luteinizing hormone (LH) levels before and after treatment were observed.
  
  
  RESULTS
  The total effective rate was 90. 0% in the treatment group which was better than 65.0% in the control group (P<0. 05). After treatment, serum E2 level significantly increased (P<0.01), with a significant difference between the two groups (P<0.05), and with a significant difference between the two groups in Kupperman symptom score index (MI) after treatment (P<0.05).
  
  
  CONCLUSIONS
  Therapeutic effect of acupuncture at the five-zangshu is better than that of Premarin for treatment of perimenopausal syndrome.
authors.affiliation: Heilongjiang University of TCM, Harbin 150040, China.
authors.forename: Hong
authors.initials: H
authors.lastname: Jin
authors.forename: Ting-ting
authors.initials: TT
authors.lastname: Liu
authors.forename: Rong
authors.initials: R
authors.lastname: Wang
mesh_terms: D015669:Acupuncture Points; D015670:Acupuncture Therapy / Q000379:methods*; D004958:Estradiol / Q000097:blood; D005260:Female; D005640:Follicle Stimulating Hormone / Q000097:blood; D006801:Humans; D007986:Luteinizing Hormone / Q000097:blood; D008875:Middle Aged; D047648:Perimenopause / Q000097:blood
chemical_list: D004958:Estradiol; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone