[Dementia complex due to HIV disease and aging].
The epidemiology of human immunodeficiency virus (HIV) infection has changed in recent years. New infections in persons over the age of 50 have increased and seropositive individuals are aging due to the widespread use of highly active antiretroviral therapies in Western countries. HIV-associated dementia remains one of the commonest neurological disorders associated with AIDS, but its progression has been modified by HAART and immune reconstitution. We review in details the epidemiology, pathogenesis, clinical features, diagnosis, and management of the HIV dementia and related cognitive disorders, and their relationship with aging.
Moulignier
Antoine
A
Service de Neurologie, Fondation Adolphe de Rothschild, Paris, France. amoulignier@fo-rothschild.fr
D015526:AIDS Dementia Complex / Q000175:diagnosis* / Q000453:epidemiology / Q000523:psychology*; D000375:Aging / Q000502:physiology*; D001921:Brain / Q000473:pathology / Q000503:physiopathology; D003072:Cognition Disorders / Q000175:diagnosis / Q000453:epidemiology; D006801:Humans; D008279:Magnetic Resonance Imaging; D009483:Neuropsychological Tests