Multiple-locus variable-number tandem-repeat analysis for rapid typing of Candida glabrata.
A multiple-locus variable-number tandem-repeat analysis (MLVA) using six microsatellite markers was assessed in 127 Candida glabrata isolates. Thirty-seven different genotypes, stable both in vitro and in vivo, were observed. The highest discriminatory power (D = 0.902) was reached by using only four markers. MLVA seems to be relevant for C. glabrata typing.
Grenouillet
Frédéric
F
Mycology-Parasitology Department, CHU Jean Minjoz, 25030, Besançon, France. fgrenouillet@chu-besancon.fr
Millon
Laurence
L
Bart
Jean-Mathieu
JM
Roussel
Sandrine
S
Biot
Isabelle
I
Didier
Emeline
E
Ong
Anne-Sophie
AS
Piarroux
Renaud
R
D041221:Candida glabrata / Q000145:classification* / Q000235:genetics; D006801:Humans; D018598:Minisatellite Repeats; D016533:Mycological Typing Techniques / Q000379:methods*