title: A novel antioxidant phenyl disaccharide from Populus tremula knotwood.
abstract: The complete characterization of two compounds obtained from the acetone extract of Populus tremula knotwood has been was achieved using LC-DAD-MS, MS/MS, IR and NMR. The new compounds were unequivocally identified as a mixture of the ester isomers of the (E) and (Z) p-coumarate of 1-O-rutinose. The isomers showed the capacity to inhibit lipid peroxidation induced by tert-butylhydroperoxide and to trap peroxyl radicals, as determined by a chemiluminescence method. These new phenyl disaccharides also showed a significant ORAC (oxygen radical absorbance capacity) value, i.e. 11.7 microM TE (Trolox Equivalents).
authors.affiliation: Department of Chemistry and Biochemistry, University of Agricultural Sciences and Veterinary Medicine, Manastur 3-5, 400372 Cluj, Napoca, Romania. neacsumro@yahoo.com
authors.forename: Madalina
authors.initials: M
authors.lastname: Neacsu
authors.forename: Vicente
authors.initials: V
authors.lastname: Micol
authors.forename: Laura
authors.initials: L
authors.lastname: Pérez-Fons
authors.forename: Stefan
authors.initials: S
authors.lastname: Willför
authors.forename: Bjarne
authors.initials: B
authors.lastname: Holmbom
authors.forename: Ricardo
authors.initials: R
authors.lastname: Mallavia
mesh_terms: D000975:Antioxidants / Q000494:pharmacology*; D002849:Chromatography, Gas; D002851:Chromatography, High Pressure Liquid; D004187:Disaccharides / Q000737:chemistry* / Q000494:pharmacology; D016166:Free Radical Scavengers / Q000737:chemistry; D015227:Lipid Peroxidation / Q000187:drug effects; D013058:Mass Spectrometry; D010545:Peroxides / Q000737:chemistry; D010636:Phenols / Q000737:chemistry* / Q000494:pharmacology; D010936:Plant Extracts / Q000737:chemistry* / Q000494:pharmacology; D032107:Populus / Q000737:chemistry*; D013056:Spectrophotometry, Ultraviolet; D013481:Superoxides / Q000737:chemistry; D014197:Trees / Q000737:chemistry; D014934:Wood
chemical_list: D000975:Antioxidants; D004187:Disaccharides; D016166:Free Radical Scavengers; D010545:Peroxides; D010636:Phenols; D010936:Plant Extracts; D013481:Superoxides; C049375:perhydroxyl radical