title: Effects of dentifrices on artificial caries like lesions: an in vitro pH cycling study.
abstract: OBJECTIVE
  To evaluate remineralising effects of three dentifrices, Vicco by Vicco Labs, India, Perioe Cavity Care by LG Care, Korea and Colgate Total by Colgate-Palmolive, Thailand on artificial caries like lesions.
  
  
  METHODS
  In vitro single-section and pH cycling model.
  
  
  METHODS
  Extracted third molars were painted with nail varnish, leaving 1 mm wide windows before placing demineralising solution for 96h to produce artificial carious lesions 150-200 miocrom deep. Teeth were then cut longitudinally into 100-150 microm thick sections and randomly assigned to three groups. Polarised light microscopy and microradiography were used to evaluate lesion depth, before and after the 10 day pH cycle. Sections in Group A were treated with Vicco by Vicco Labs, India (-ve control), Group B were treated with Perioe Cavity Care by LG Care, Korea and Group C were treated with Colgate Total by Colgate-Palmolive, Thailand.
  
  
  RESULTS
  Mean lesion depths in Groups B and C reduced by 7% and 12% respectively, whereas lesion depth increased by 13% in Group A. Comparisons made among groups using ANOVA and Student-Newman-Keuls tests showed that three groups were significantly different from each other (p < 0.05).
  
  
  CONCLUSIONS
  Perioe Cavity Care and Colgate Total remineralised initial carious lesions. However, the remineralising potential of Colgate Total was higher than that of Perioe Cavity Care.
authors.affiliation: School of dentistry and Oral Health, Griffith University, Southport QLD, Australia.
authors.forename: R
authors.initials: R
authors.lastname: Rana
authors.forename: A
authors.initials: A
authors.lastname: Itthagarun
authors.forename: N M
authors.initials: NM
authors.lastname: King
mesh_terms: D002327:Cariostatic Agents / Q000627:therapeutic use; D045424:Complex Mixtures / Q000627:therapeutic use; D003731:Dental Caries / Q000473:pathology / Q000503:physiopathology / Q000517:prevention & control*; D003802:Dentifrices / Q000627:therapeutic use*; D005459:Fluorides / Q000627:therapeutic use; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008852:Microradiography; D008859:Microscopy, Polarization; D008964:Molar, Third; D012824:Silicic Acid; D012969:Sodium Fluoride / Q000627:therapeutic use; D013997:Time Factors; D017001:Tooth Demineralization / Q000473:pathology / Q000503:physiopathology; D014089:Tooth Remineralization; D014100:Toothpastes; D014260:Triclosan / Q000627:therapeutic use
chemical_list: D002327:Cariostatic Agents; D045424:Complex Mixtures; D003802:Dentifrices; D014100:Toothpastes; C546060:hydrated silica gel-based toothpaste; D012824:Silicic Acid; D014260:Triclosan; D012969:Sodium Fluoride; D005459:Fluorides