title: Surgical results and prognosis of patients with primary bronchogenic carcinoma aged less than 36 years.
abstract: OBJECTIVE
  This study reports on the demographic features, clinico-pathological results and prognoses of patients aged less than 36 years diagnosed with non-small cell lung cancer (NSCLC).
  
  
  METHODS
  This is an observational study of patients with primary NSCLC who had a surgical procedure at a tertiary thoracic surgery centre in Turkey. Data collected were age, gender, history of smoking, symptoms, postoperative histopathological diagnosis, stage, surgical procedure and survival.
  
  
  RESULTS
  Of the 31 patients in the study, 27 were male (87%) and the median age was 32 years (10-35 years). Nineteen patients were smokers (61.2%). The most common presenting symptom was cough (n = 23, 67.7%). Histopathological diagnosis was squamous cell carcinoma (SCC, n = 17), adenocarcinoma (n = 12), lymphoepithelioma-like carcinoma (n = 1) and undifferentiated carcinoma (n = 1). Staging of the 17 patients with SCC (58.8%) was stage I and II (n = 10, 58%), and stage III (n = 7, 41%). Staging of the 13 patients with adenocarcinoma was stage IV (n = 2, 16%) and stage III patients (n = 8, 66%). Follow-up data were available on 22 patients (71%) and showed a median survival of 17.2 months. Two and 5-year survival rates were 54.5% and 45.5%, respectively.
  
  
  CONCLUSIONS
  SCC comprised a relatively high proportion of NSCLC in these younger patients. Aggressive multimodality treatment may achieve satisfactory 2- and 5-year survival rates in young patients with NSCLC who usually present with advanced disease.
authors.affiliation: Department of Thoracic Surgery, Kahramanmaras Sutcu Imam University, School of Medicine, Kahramanmaras, Turkey. drhasanturut@yahoo.com
authors.forename: Hasan
authors.initials: H
authors.lastname: Türüt
authors.forename: Irfan
authors.initials: I
authors.lastname: Tastepe
authors.forename: Sadi
authors.initials: S
authors.lastname: Kaya
authors.forename: Mehmet
authors.initials: M
authors.lastname: Sirmali
authors.forename: Suat
authors.initials: S
authors.lastname: Gezer
authors.forename: Gurhan
authors.initials: G
authors.lastname: Oz
authors.forename: Gokturk
authors.initials: G
authors.lastname: Findik
authors.forename: Guven
authors.initials: G
authors.lastname: Cetin
mesh_terms: D000230:Adenocarcinoma / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D000293:Adolescent; D000328:Adult; D002283:Carcinoma, Bronchogenic / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D002294:Carcinoma, Squamous Cell / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D009367:Neoplasm Staging; D011379:Prognosis