title: [Study of cardiopulmonary adaptation during exercise in patients after extracardiac conduit total cavopulmonary connection].
abstract: OBJECTIVE
  To study cardiopulmonary physiology during exercise in patients after extracardiac total cavopulmonary connection (ECTCPC).
  
  
  METHODS
  Twenty-six patients were studied after ECTCPC by exercise testing with bicycle treadmill protocol. Heart rate (HR), blood pressure (BP), respiratory frequency (RF) and pulse oxygen saturation (SpO(2)) were measured continuously; twenty-six patients suffered from Fallot 4 underwent biventricular repair were also studied as control group.
  
  
  RESULTS
  In ECTCPC group, HR, BP, SpO(2) and RF all increased with exercise below 3 grade; when exceed 4 grade, BP, SpO(2) decreased and RF kept increasing. Compared with control group, HR, RF were higher (t = 2.13, P < 0.05; t = 2.31, P < 0.05), SpO(2) was lower (t = 2.46, P < 0.05) under the quiescent condition; When exceed 3 grade, HR, BP, SpO(2) decreased more significantly, but RF increased continuously. In fenestration group after ECTCPC, HR reached the top at 5 grades, but in group without fenestration it reached the top at 3 grades; In the whole process of exercising, RF kept higher and SpO(2) kept lower in fenestration group.
  
  
  CONCLUSIONS
  The ECTCPC patients showed obviously exercise limitation. Totally bypass of sinoatrial node in this operation may have some adverse effects on the integer regulation of HR.
authors.affiliation: Department of Cardiovascular Surgery, the General Hospital of Shenyang Military Command, Shenyang 110016, China. yzt1210@hotmail.com.
authors.forename: Zong-tao
authors.initials: ZT
authors.lastname: Yin
authors.forename: Hong-yu
authors.initials: HY
authors.lastname: Zhu
authors.forename: Zeng-wei
authors.initials: ZW
authors.lastname: Wang
authors.forename: Ren-fu
authors.initials: RF
authors.lastname: Zhang
authors.forename: Nan-bin
authors.initials: NB
authors.lastname: Zhang
authors.forename: Min-hua
authors.initials: MH
authors.lastname: Fang
authors.forename: Heng-chang
authors.initials: HC
authors.lastname: Song
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D005080:Exercise Test; D005260:Female; D005500:Follow-Up Studies; D018729:Fontan Procedure / Q000379:methods*; D006330:Heart Defects, Congenital / Q000503:physiopathology* / Q000601:surgery; D006801:Humans; D008297:Male; D010807:Physical Endurance / Q000502:physiology*; D011184:Postoperative Period