title: Is the SRS-22 instrument responsive to change in adult scoliosis patients having primary spinal deformity surgery?
abstract: METHODS
  Multicenter study.
  
  
  OBJECTIVE
  The purpose of this study is to prospectively analyze responsiveness of the SRS-22 to change at 1 and 2 years following primary surgery.
  
  
  BACKGROUND
  A number of efforts have been directed at validation of the SRS-22 instrument in the setting of adolescent and adult spinal deformity. However, few have extensively analyzed the ability of the instrument to detect change (brought on by surgical treatment) in adult scoliosis patients.
  
  
  METHODS
  A multicenter prospective series of consecutive adult scoliosis patients (all primary/no revisions) were administered SRS-22, Oswestry Disability Index (ODI)and Short Form-12 (SF-12) questionnaires preoperation and 1 and 2 years postoperation. Fifty-six patients had preoperative, 1-year postoperative, and 2-year postoperative data.
  
  
  RESULTS
  The greatest changes from preoperation to 2-year postoperation were the SRS self-image domain followed by SRS total, SRS pain, and ODI scores. SRS pain and function scores significantly (P < 0.05) improved from 1-year to 2-year postoperation. There were not substantial differences in the outcome measures according to age or curve type. All outcome measures except SF-12 mental health showed statistically significant (P < 0.05) improvement from baseline to 2-year follow-up.
  
  
  CONCLUSIONS
  Based on these 3 outcome tools, the greatest responsiveness to change was demonstrated by the SRS self-image domain followed by SRS total, then SRS pain, then ODI. This suggests that the SRS tool is more responsive than ODI, which is more responsive than SF-12 to change brought on by primary surgical treatment of adult scoliosis patients. Surgical treatment in adult scoliosis significantly improved pain, self-image, and function based on the health-related quality of life measures used in this study.
authors.affiliation: Washington University, St. Louis, MO 63110, USA. bridwellk@wudosis.wustl.edu
authors.forename: Keith H
authors.initials: KH
authors.lastname: Bridwell
authors.forename: Sigurd
authors.initials: S
authors.lastname: Berven
authors.forename: Steven
authors.initials: S
authors.lastname: Glassman
authors.forename: Christopher
authors.initials: C
authors.lastname: Hamill
authors.forename: William C
authors.initials: WC
authors.lastname: Horton
authors.forename: Lawrence G
authors.initials: LG
authors.lastname: Lenke
authors.forename: Frank
authors.initials: F
authors.lastname: Schwab
authors.forename: Christine
authors.initials: C
authors.lastname: Baldus
authors.forename: Michael
authors.initials: M
authors.lastname: Shainline
mesh_terms: D000328:Adult; D001416:Back Pain / Q000209:etiology*; D004185:Disability Evaluation; D005260:Female; D006304:Health Status; D006801:Humans; D008159:Lumbar Vertebrae / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D010147:Pain Measurement; D017060:Patient Satisfaction; D011446:Prospective Studies; D011788:Quality of Life; D020127:Recovery of Function; D015203:Reproducibility of Results; D012600:Scoliosis / Q000150:complications / Q000175:diagnosis* / Q000503:physiopathology / Q000523:psychology / Q000601:surgery; D012649:Self Concept; D012720:Severity of Illness Index; D011795:Surveys and Questionnaires; D013904:Thoracic Vertebrae / Q000601:surgery*; D013997:Time Factors; D016896:Treatment Outcome; D014481:United States