[Severe toxic diarrhoea in cyclosporin treated 11-years old girl with nephrotic syndrome].
A 11-years old cyclosporin-treated girl with nephrotic syndrome, complicated by severe toxic diarrhoea with excessive metabolic alkalosis and dyselektrolitemia (hyponatremia, hypokaliemia, hypochloremia) and transient immunoglobulin deficiency is reported. Ultrasonography shows thickeness of the colonic wall as a symptom of colonic inflammation. After discontinuation of cyclosporin therapy, excluding infectious origin of diarrhoea (bacterial, viral and fungal infection), partial parenteral nutrition, enteral nutrition (Peptisorb), probiotics and antidiarrhoeal drugs were used in the treatment. After introducing steroids orally (Entocort) complete resolution of symptoms were observed.
Stawarski
Andrzej
A
Akademia Medyczna we Wrocławiu, II Katedra i Klinika Pediatrii, Gastroenterologii i Zywienia. as.stawarski@poczta.onet.pl
Iwańczak
Barbara
B
Wawro
Anna
A
Iwańczak
Franciszek
F
Piasecka
Agata
A
Sarnowska
Marta
M
Makulska
Irena
I
D002648:Child; D003092:Colitis / Q000139:chemically induced* / Q000000981:diagnostic imaging; D016572:Cyclosporine / Q000009:adverse effects*; D003967:Diarrhea / Q000139:chemically induced*; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects*; D009404:Nephrotic Syndrome / Q000188:drug therapy*; D014463:Ultrasonography
D007166:Immunosuppressive Agents; D016572:Cyclosporine