Cellular motors for molecular manufacturing.
Cells are composed of macromolecular structures of various sizes that act individually or collectively to maintain their viability and perform their function within the organism. This review focuses on one structure, the microtubule, and one of the motor proteins that move along it, conventional kinesin (kinesin 1). Recent work on the cellular functions of kinesins, such as the organization of microtubules during cellular division and the movement of the organelles and vesicles, offers insights into how biological motors might prove useful for organizing structures in engineered environments.
Dinu
C Z
CZ
Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany. dinuz@rpi.edu
Chrisey
D B
DB
Diez
S
S
Howard
J
J
D001692:Biological Transport / Q000502:physiology; D016547:Kinesins / Q000502:physiology*; D008870:Microtubules / Q000502:physiology*
D016547:Kinesins