title: Modelling the effects of different fracture geometries and healing stages on ultrasound signal loss across a long bone fracture.
abstract: The effect on the signal amplitude of ultrasonic waves propagating along cortical bone plates was modelled using a 2D Finite Difference code. Different healing stages, represented by modified fracture geometries were introduced to the plate model. A simple transverse and oblique fracture filled with water was introduced to simulate the inflammatory stage. Subsequently, a symmetric external callus surrounding a transverse fracture was modelled to represent an advanced stage of healing. In comparison to the baseline (intact plate) data, a large net loss in signal amplitude was produced for the simple transverse and oblique cases. Changing the geometry to an external callus with different mechanical properties caused the net loss in signal amplitude to reduce significantly. This relative change in signal amplitude as the geometry and mechanical properties of the fracture site change could potentially be used to monitor the healing process.
authors.affiliation: Department of Mechanical Engineering, University of Bath, Bath, Avon, UK. spd@inorbit.com
authors.forename: S P
authors.initials: SP
authors.lastname: Dodd
authors.forename: A W
authors.initials: AW
authors.lastname: Miles
authors.forename: S
authors.initials: S
authors.lastname: Gheduzzi
authors.forename: V F
authors.initials: VF
authors.lastname: Humphrey
authors.forename: J L
authors.initials: JL
authors.lastname: Cunningham
mesh_terms: D000818:Animals; D001842:Bone and Bones / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D002417:Cattle; D003198:Computer Simulation; D017102:Fracture Healing / Q000502:physiology*; D050723:Fractures, Bone / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D006801:Humans; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D008954:Models, Biological; D012542:Scattering, Radiation; D014463:Ultrasonography