title: Do ligand binding and solvent exclusion alter the electrostatic character within the oxyanion hole of an enzymatic active site?
authors.affiliation: Departments of Chemistry and Biochemistry, Stanford University, Stanford, California 94305-5307, USA.
authors.forename: Paul A
authors.initials: PA
authors.lastname: Sigala
authors.forename: Aaron T
authors.initials: AT
authors.lastname: Fafarman
authors.forename: Patrick E
authors.initials: PE
authors.lastname: Bogard
authors.forename: Steven G
authors.initials: SG
authors.lastname: Boxer
authors.forename: Daniel
authors.initials: D
authors.lastname: Herschlag
mesh_terms: D000838:Anions; D001665:Binding Sites; D007700:Kinetics; D008024:Ligands; D010100:Oxygen / Q000737:chemistry* / Q000378:metabolism; D016958:Pseudomonas putida / Q000201:enzymology; D012997:Solvents / Q000737:chemistry; D017550:Spectroscopy, Fourier Transform Infrared; D055672:Static Electricity; D013251:Steroid Isomerases / Q000737:chemistry* / Q000378:metabolism; D013861:Thiocyanates / Q000737:chemistry
chemical_list: D000838:Anions; D008024:Ligands; D012997:Solvents; D013861:Thiocyanates; D013251:Steroid Isomerases; D010100:Oxygen