title: How can hepatitis C be prevented in the long term?
abstract: Significant advances have been made in preventing HIV infection among injectors but we still know little about preventing hepatitis C (HCV). Both prevalence and incidence of hepatitis C can remain high among IDUs even in the context of widespread implementation of harm reduction programmes. We need to develop new ways to fill the knowledge gap regarding HCV prevention. One way is to learn from the experts--those IDUs who, after long-term injection in social milieus of high hepatitis C prevalence, nonetheless remain uninfected. We describe a recently commenced program of research that focuses on understanding the strategies, behaviours, and environmental factors associated with "staying safe". This represents a 180-degree turn in IDU research where the focus has traditionally been on risk. Since social, cultural and environmental factors, as well as the vagaries of human strategic discovery by drug users can vary among localities, researchers in four different contexts--New York City, Valencia, Sydney and London--are collaborating in parallel Staying Safe studies. These studies aim to provide the conceptual basis for developing a new generation of HCV prevention programs to assist both new and experienced IDUs to remain uninfected over the long run.
authors.affiliation: Center for Drug Use and HIV Research, National Development Research Institutes, New York City, NY, United States. mateu-gelabert@ndri.org <mateu-gelabert@ndri.org>
authors.forename: Pedro
authors.initials: P
authors.lastname: Mateu-Gelabert
authors.forename: Carla
authors.initials: C
authors.lastname: Treloar
authors.forename: Víctor Agulló
authors.initials: VA
authors.lastname: Calatayud
authors.forename: Milagros
authors.initials: M
authors.lastname: Sandoval
authors.forename: Juan Carlos Valderrama
authors.initials: JC
authors.lastname: Zurián
authors.forename: Lisa
authors.initials: L
authors.lastname: Maher
authors.forename: Tim
authors.initials: T
authors.lastname: Rhodes
authors.forename: Samuel R
authors.initials: SR
authors.lastname: Friedman
mesh_terms: D040261:Harm Reduction; D015438:Health Behavior; D006526:Hepatitis C / Q000453:epidemiology / Q000517:prevention & control* / Q000635:transmission; D006801:Humans; D015994:Incidence; D007391:International Cooperation; D008131:London / Q000453:epidemiology; D009313:National Health Programs; D018671:Needle-Exchange Programs; D009517:New South Wales / Q000453:epidemiology; D009518:New York / Q000453:epidemiology; D015995:Prevalence; D012107:Research Design; D012944:Social Support; D012959:Socioeconomic Factors; D013030:Spain / Q000453:epidemiology; D015819:Substance Abuse, Intravenous / Q000453:epidemiology* / Q000523:psychology; D013997:Time Factors