Distribution of serum measles-neutralizing antibodies according to age in women of childbearing age in France in 2005-2006: impact of routine immunization.
Measles antibody titers were measured in 210 French women. Ninety-four percent had protective values (>120 mIU/mL). Geometric mean titers were significantly different (P < 0.001) between women born before and after 1983, when measles vaccination was recommended (731 and 1358 mIU/mL, respectively). geometric mean titers in 4 age cohorts decreased significantly (P < 0.001) with increasing birth year. These data may help identify the appropriate age for infant vaccination.
Pinquier
Didier
D
Centre Hospitalier Universitaire, Rouen, France. didier.pinquier@chu-rouen.fr
Gagneur
Arnaud
A
Aubert
Marie
M
Brissaud
Olivier
O
Le Guen
Christèle Gras
CG
Hau-Rainsard
Isabelle
I
Picherot
Georges
G
De Pontual
Loïc
L
Stephan
Jean-Louis
JL
Reinert
Philippe
P
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000914:Antibodies, Viral / Q000097:blood*; D002648:Child; D005260:Female; D005602:France; D006801:Humans; D008458:Measles Vaccine / Q000276:immunology*; D009500:Neutralization Tests; D013997:Time Factors
D000914:Antibodies, Viral; D008458:Measles Vaccine