title: Impact of changing epidemiology of gastroesophageal reflux disease on its diagnosis and treatment.
abstract: Gastroesophageal reflux disease (GERD) has emerged as one of the most common diseases in modern civilization. This article reviews selected changes in epidemiology of GERD during the past decade and provides information on treatment options with a focus on the impact of GERD and potential role of laparoscopic antireflux surgery in patients with diabetes mellitus, obesity, liver cirrhosis, at the extremes of life age and in immunocompromised individuals such as liver and lung transplant recipients.
authors.affiliation: Department of Surgery, Mayo Clinic Jacksonville, Jacksonville, FL 32224, USA.
authors.forename: Hugo
authors.initials: H
authors.lastname: Bonatti
authors.forename: Sami R
authors.initials: SR
authors.lastname: Achem
authors.forename: Ronald A
authors.initials: RA
authors.lastname: Hinder
mesh_terms: D000328:Adult; D000368:Aged; D002648:Child; D015897:Comorbidity; D003920:Diabetes Mellitus / Q000453:epidemiology; D005764:Gastroesophageal Reflux / Q000175:diagnosis / Q000453:epidemiology* / Q000503:physiopathology / Q000628:therapy; D006801:Humans; D016867:Immunocompromised Host; D008103:Liver Cirrhosis / Q000453:epidemiology; D016031:Liver Transplantation; D009765:Obesity / Q000453:epidemiology