title: HLA analysis of Sri Lankan Sinhalese predicts North Indian origin.
abstract: The origin of the Sinhalese population of Sri Lanka is debated. We subtyped HLA-A*02 in 101 Sinhalese and observed a preponderance of the rare allele HLA-A*0211 which was similar to reported frequencies in northern India. Taken with low-resolution typing for the remaining A, B, C, DR and DQ alleles, these data suggest a North Indian origin for the Sri Lankan Sinhalese.
authors.affiliation: MRC Human Immunology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.
authors.forename: G N
authors.initials: GN
authors.lastname: Malavige
authors.forename: T
authors.initials: T
authors.lastname: Rostron
authors.forename: S L
authors.initials: SL
authors.lastname: Seneviratne
authors.forename: S
authors.initials: S
authors.lastname: Fernando
authors.forename: S
authors.initials: S
authors.lastname: Sivayogan
authors.forename: A
authors.initials: A
authors.lastname: Wijewickrama
authors.forename: G S
authors.initials: GS
authors.lastname: Ogg
mesh_terms: D044466:Asian People / Q000208:ethnology* / Q000235:genetics*; D005787:Gene Frequency; D006680:HLA Antigens / Q000235:genetics*; D015234:HLA-A Antigens / Q000235:genetics*; D015789:HLA-A2 Antigen; D006801:Humans; D007194:India / Q000208:ethnology; D013188:Sri Lanka / Q000208:ethnology
chemical_list: D006680:HLA Antigens; D015234:HLA-A Antigens; C524866:HLA-A*02 antigen; D015789:HLA-A2 Antigen