title: Linear, redox modified DNA probes as electrochemical DNA sensors.
abstract: We show here that hybridization-linked changes in the dynamics of a redox-modified, electrode-bound linear (as opposed to stem-loop) probe DNA produce large changes in Faradaic current, allowing for the ready detection of target oligonucleotides.
authors.affiliation: Department of Chemistry and Biochemistry, University of California, Santa Barbara, CA 93106, USA.
authors.forename: Francesco
authors.initials: F
authors.lastname: Ricci
authors.forename: Rebecca Y
authors.initials: RY
authors.lastname: Lai
authors.forename: Kevin W
authors.initials: KW
authors.lastname: Plaxco
mesh_terms: D015374:Biosensing Techniques / Q000379:methods; D004247:DNA / Q000032:analysis*; D015342:DNA Probes / Q000138:chemical synthesis* / Q000737:chemistry; D004563:Electrochemistry; D009838:Oligodeoxyribonucleotides / Q000032:analysis*
chemical_list: D015342:DNA Probes; D009838:Oligodeoxyribonucleotides; D004247:DNA