title: [Severe toxic diarrhoea in cyclosporin treated 11-years old girl with nephrotic syndrome].
abstract: A 11-years old cyclosporin-treated girl with nephrotic syndrome, complicated by severe toxic diarrhoea with excessive metabolic alkalosis and dyselektrolitemia (hyponatremia, hypokaliemia, hypochloremia) and transient immunoglobulin deficiency is reported. Ultrasonography shows thickeness of the colonic wall as a symptom of colonic inflammation. After discontinuation of cyclosporin therapy, excluding infectious origin of diarrhoea (bacterial, viral and fungal infection), partial parenteral nutrition, enteral nutrition (Peptisorb), probiotics and antidiarrhoeal drugs were used in the treatment. After introducing steroids orally (Entocort) complete resolution of symptoms were observed.
authors.affiliation: Akademia Medyczna we Wrocławiu, II Katedra i Klinika Pediatrii, Gastroenterologii i Zywienia. as.stawarski@poczta.onet.pl
authors.forename: Andrzej
authors.initials: A
authors.lastname: Stawarski
authors.forename: Barbara
authors.initials: B
authors.lastname: Iwańczak
authors.forename: Anna
authors.initials: A
authors.lastname: Wawro
authors.forename: Franciszek
authors.initials: F
authors.lastname: Iwańczak
authors.forename: Agata
authors.initials: A
authors.lastname: Piasecka
authors.forename: Marta
authors.initials: M
authors.lastname: Sarnowska
authors.forename: Irena
authors.initials: I
authors.lastname: Makulska
mesh_terms: D002648:Child; D003092:Colitis / Q000139:chemically induced* / Q000000981:diagnostic imaging; D016572:Cyclosporine / Q000009:adverse effects*; D003967:Diarrhea / Q000139:chemically induced*; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects*; D009404:Nephrotic Syndrome / Q000188:drug therapy*; D014463:Ultrasonography
chemical_list: D007166:Immunosuppressive Agents; D016572:Cyclosporine