title: A dual near-infrared pH fluorescent probe and its application in imaging of HepG2 cells.
abstract: A dual near-infrared pH fluorescent probe has been designed, synthesized and applied to HepG2 cells, with a pK(a) value of 5.14 under acidic conditions and 11.31 under basic conditions, which is valuable for studying acidic organelles in living cells and pH changes in chemical systems.
authors.affiliation: College of Chemistry, Chemical Engineering and Materials Science, Engineering Research Center of Pesticide and Medicine Intermediate Clean Production, Shandong Normal University, Jinan 250014, P. R. China. tangb@sdnu.edu.cn
authors.forename: Bo
authors.initials: B
authors.lastname: Tang
authors.forename: Xia
authors.initials: X
authors.lastname: Liu
authors.forename: Kehua
authors.initials: K
authors.lastname: Xu
authors.forename: Hui
authors.initials: H
authors.lastname: Huang
authors.forename: Guiwen
authors.initials: G
authors.lastname: Yang
authors.forename: Liguo
authors.initials: L
authors.lastname: An
mesh_terms: D005456:Fluorescent Dyes / Q000138:chemical synthesis*; D051272:Glucose Transporter Type 1; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007700:Kinetics; D015335:Molecular Probes; D015394:Molecular Structure; D019265:Spectroscopy, Near-Infrared / Q000379:methods
chemical_list: D005456:Fluorescent Dyes; D051272:Glucose Transporter Type 1; D015335:Molecular Probes; C495677:SLC2A1 protein, human