title: From genes to shape: regulatory interactions in leaf development.
abstract: In the past two years novel connections were described between auxin function and transcription factor patterning systems involved in both leaf initiation and elaboration of leaf axial patterning. A cascade of small RNA-based regulatory steps was suggested to facilitate delimitation of cell types comprising the upper versus lower parts of the leaf. Developmental regulation of cellular growth emerged as a crucial component in regulation of leaf form with TCP and CUC2 transcription factors playing a key role in this process. Finally, cis-regulatory evolution of developmental genes emerged as a process that likely contributed to diversification of leaf form, while studies in seedless land plants have begun to elucidate the ancestral and derived aspects of leaf development pathways.
authors.affiliation: Department of Plant Sciences, University of Oxford, South Parks Road, Oxford OX1 3RB, UK.
authors.forename: Michalis
authors.initials: M
authors.lastname: Barkoulas
authors.forename: Carla
authors.initials: C
authors.lastname: Galinha
authors.forename: Stephen P
authors.initials: SP
authors.lastname: Grigg
authors.forename: Miltos
authors.initials: M
authors.lastname: Tsiantis
mesh_terms: D017360:Arabidopsis / Q000033:anatomy & histology / Q000235:genetics / Q000254:growth & development*; D029681:Arabidopsis Proteins / Q000235:genetics*; D005075:Biological Evolution; D019521:Body Patterning / Q000235:genetics; D049109:Cell Proliferation; D018519:Meristem / Q000235:genetics / Q000254:growth & development; D018515:Plant Leaves / Q000033:anatomy & histology / Q000235:genetics / Q000254:growth & development
chemical_list: D029681:Arabidopsis Proteins