title: Novel application of Leuckart-Wallach reaction for synthesis of tetrahydro-1,4-benzodiazepin-5-ones library.
abstract: A novel and efficient strategy has been developed to synthesize privileged tetrahydro-1,4-benzodiazepines with excellent yields and purities; this synthetic pathway was established by the revitalization of the Leuckart-Wallach (LW) reaction via solid-phase synthesis.
authors.affiliation: Department of Chemistry, Seoul National University, Seoul 151-747, Korea.
authors.forename: Sung-Chan
authors.initials: SC
authors.lastname: Lee
authors.forename: Seung Bum
authors.initials: SB
authors.lastname: Park
mesh_terms: D001569:Benzodiazepines / Q000138:chemical synthesis* / Q000737:chemistry*; D020650:Combinatorial Chemistry Techniques; D015394:Molecular Structure
chemical_list: D001569:Benzodiazepines