title: Amniotic membrane transplantation for intraoperative conjunctival repair during trabeculectomy with mitomycin C.
abstract: OBJECTIVE
  To describe the use of amniotic membrane (AM) transplantation for the repair of conjunctival buttonholes during trabeculectomy with mitomycin C.
  
  
  METHODS
  Four eyes of 3 patients with thin conjunctiva, precluding watertight conjunctival closure at the incision site with suturing, underwent intraoperative AM grafts over the leaking areas.
  
  
  RESULTS
  In all eyes, a functional, nonleaking bleb was achieved. At the latest follow-up (8 to 30 mo), all eyes had intraocular pressures of 12 mm Hg or less without medications.
  
  
  CONCLUSIONS
  AM transplantation was effective in the intraoperative closure of conjunctival buttonholes which developed at the incision line in 4 eyes. This intervention may be a useful addition to the glaucoma surgeon's repertoire of surgical techniques.
authors.affiliation: McGill University, Quebec, Canada.
authors.forename: Gisèle
authors.initials: G
authors.lastname: Li
authors.forename: Thomas
authors.initials: T
authors.lastname: O'Hearn
authors.forename: Samuel
authors.initials: S
authors.lastname: Yiu
authors.forename: Brian A
authors.initials: BA
authors.lastname: Francis
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000650:Amnion / Q000637:transplantation*; D003131:Combined Modality Therapy; D003228:Conjunctiva / Q000293:injuries*; D017889:Exfoliation Syndrome / Q000628:therapy; D005131:Eye Injuries / Q000601:surgery*; D005260:Female; D005902:Glaucoma, Open-Angle / Q000628:therapy; D006801:Humans; D007431:Intraoperative Complications; D016685:Mitomycin / Q000008:administration & dosage*; D014130:Trabeculectomy
chemical_list: D016685:Mitomycin