Copper-catalyzed oxidative desulfurization-oxygenation of thiocarbonyl compounds using molecular oxygen: an efficient method for the preparation of oxygen isotopically labeled carbonyl compounds.
A novel copper-catalyzed oxidative desulfurization reaction of thiocarbonyl compounds, using molecular oxygen as an oxidant and leading to formation of carbonyl compounds, has been developed, and the utility of the process is demonstrated by its application to the preparation of a carbonyl-18O labeled sialic acid derivative.
Shibahara
Fumitoshi
F
Department of Chemistry, Faculty of Engineering, Gifu University, Yanagido, Gifu 501-1193, Japan. fshiba@gifu-u.ac.jp
Suenami
Aiko
A
Yoshida
Atsunori
A
Murai
Toshiaki
T
D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D007553:Isotope Labeling; D007659:Ketones / Q000737:chemistry*; D010084:Oxidation-Reduction; D010100:Oxygen / Q000737:chemistry*; D013455:Sulfur / Q000737:chemistry*
D007659:Ketones; D013455:Sulfur; D003300:Copper; D010100:Oxygen