Surgical interventions for emphysema.
Three surgical procedures are pertinent to the treatment of end-stage emphysema: giant bullectomy, lung volume reduction surgery (LVRS), and lung transplantation. Patients with localized disease manifesting as a giant bulla that compresses adjacent healthy lung tissues can be offered bullectomy. Patients with diffuse disease can be offered LVRS, lung transplantation, or staged LVRS/lung transplant, depending on multiple factors including age, lung function parameters, lobar predominance, and whether the disease is uni- or bilateral. Since end-stage emphysema is refractory to most medical treatment, surgery is often the only remaining option.
Camp
Phillip Cabot
PC
Harvard Medical School, Lung Transplant Program, Division of Thoracic Surgery, Brigham and Women's Hospital, Boston, Massachusetts 02115-6195, USA.
Sugarbaker
David J
DJ
D006801:Humans; D016040:Lung Transplantation / Q000379:methods*; D018579:Patient Selection; D011013:Pneumonectomy / Q000379:methods*; D011656:Pulmonary Emphysema / Q000175:diagnosis / Q000601:surgery*; D012720:Severity of Illness Index; D016896:Treatment Outcome