Organisation and quality of primary surgical intervention for ovarian cancer in Denmark.
BACKGROUND
The positive effect on survival of maximal primary cytoreductive surgery for ovarian cancer is well established, and the highest rates of optimal cytoreduction are achieved by gynecological oncologists. Danish women have not only one of the highest incidences of ovarian cancer, but also the highest mortality rate. From 1981 to 1989, the overall Danish optimal debulking rate was 25% in patients with stage III and IV tumors. The primary aim of the present study was, therefore, to evaluate the organisation and quality of current primary surgical intervention for ovarian cancer in Denmark.


METHODS
All women diagnosed with epithelial ovarian carcinoma (DC56) were identified through the Danish National Patient Registry during the study period from 1 July 2002 to 31 December 2003, and surgical notes and histopathology were evaluated by a board of 7 gynecological-oncologists, focusing on maximal cytoreduction.


RESULTS
For stage III, the nationwide optimal debulking rate was 39%, significantly higher in the major hospitals (49%) versus other hospitals (29%) (p<0.005). In 19% of cases, there was insufficient information to evaluate debulking from the surgical notes, significantly less at the major hospitals versus other hospitals (12 versus 25%, p<0.001).


CONCLUSIONS
In Denmark, the quality of the primary surgical intervention for ovarian cancer is not optimal. In order to enhance survival, compliance with international guidelines and improved registration of the surgical procedures in clinical databases are mandatory.
Marx
Charlotte
C
Department of Gynecology, Juliane Marie Centre, Rigshospitalet, Blegdamsvej, Copenhagen, Denmark. charlotte.marx@rh.hosp.dk
Bendixen
Anette
A
Høgdall
Claus
C
Ottosen
Christian
C
Kehlet
Henrik
H
Ottesen
Bent
B
D002173:Cancer Care Facilities / Q000458:organization & administration / Q000592:standards*; D003718:Denmark / Q000453:epidemiology; D005260:Female; D013509:Gynecologic Surgical Procedures / Q000592:standards*; D006801:Humans; D009367:Neoplasm Staging; D010043:Outcome and Process Assessment, Health Care; D010051:Ovarian Neoplasms / Q000453:epidemiology* / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D018024:Peer Review, Health Care; D011183:Postoperative Complications; D010818:Practice Patterns, Physicians' / Q000592:standards*; D011787:Quality of Health Care; D012042:Registries