Whipple's disease in mentally retarded patients: report of two cases.
Of 21 patients diagnosed with Whipple's disease (WD) by polymerase chain reaction (PCR), 3 were mentally retarded. We describe 2 of these patients, both of whom had WD in the central nervous system. WD was confirmed with PCR on blood and, for 1 patient, also on cerebrospinal fluid (CSF).
Pettersson
Annika
A
Department of Medical Microbiology and Infection Control, VU University Medical Centre, Amsterdam, The Netherlands. a.pettersson@vumc.nl
van Winsen
Lisa
L
van Oosten
Bob
B
Kramers
Cornelis
C
van de Ven
Andre
A
Savelkoul
Paul
P
van Agtmael
Michiel
M
D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008607:Intellectual Disability / Q000150:complications*; D016133:Polymerase Chain Reaction; D008061:Whipple Disease / Q000097:blood / Q000134:cerebrospinal fluid / Q000175:diagnosis* / Q000188:drug therapy
D000900:Anti-Bacterial Agents