Drug rash with eosinophilia and systemic symptoms (DRESS) syndrome: suspected association with titanium bioprosthesis.
Drug rash with eosinophilia and systemic symptoms (DRESS), also known as hypersensitivity syndrome, is an idiosyncratic drug reaction presenting with fever, diffuse lymphadenopathy, exfoliative dermatitis, and visceral involvement, which may include hepatitis, pneumonitis, pericarditis, myocarditis, nephritis, and colitis. This report describes a 19-year-old, previously healthy man with manifestations of hypersensitivity (DRESS) syndrome after acquiring a titanium bioprosthesis for a spinal fracture. To our knowledge, there have been no prior reports of DRESS syndrome in association with titanium bioprosthetic implants.
Nawaz
Fareha
F
Veterans Affairs Medical Center and Department of Medicine, University of Tennessee Health Science Center, Memphis, Tennessee, USA.
Wall
Barry M
BM
D000328:Adult; D001705:Bioprosthesis / Q000009:adverse effects*; D003875:Drug Eruptions; D004342:Drug Hypersensitivity / Q000175:diagnosis*; D006801:Humans; D006968:Hypersensitivity, Delayed / Q000139:chemically induced*; D007668:Kidney / Q000000981:diagnostic imaging / Q000187:drug effects / Q000473:pathology; D008297:Male; D016103:Spinal Fractures / Q000628:therapy; D013577:Syndrome; D014025:Titanium / Q000009:adverse effects*; D014057:Tomography, X-Ray Computed
D014025:Titanium