title: Antioxidant activity of a new aromatic geranyl derivative of the resinous exudates from Heliotropium glutinosum Phil.
abstract: Heliotropium glutinosum Phil. (Heliotropiceae) is a resinous bush that grows at a height of 2000 m in Chañaral, Chile. From the resinous exudates of Heliotropium glutinosum Phil. a new aromatic geranyl derivative: 4-methoxy-3-[(2)-7'-methyl-3'-hydroxymethyl-2',6'-octadienyl] phenol (1) and three flavonoids: 5,3'-dihydroxy-7,4'-dimethoxyflavanone (2), 5,4'-dihydroxy-7-methoxyflavanone (3) and 4'-acetyl-5-hydroxy-7-methoxyflavanone (4) were isolated and their structures were determined. Their antioxidant activity were evaluated using the bleaching of ABTS and DPPH derived cation radical methods and expressed in terms of FRE (fast reacting equivalents) and TRE (total reacting equivalents), where FRE is a good measure of the quick protection of a given compound against oxidants and TRE measures the degree of long-term protection of the antioxidant, or how effective it is against a strong oxidative stress.
authors.affiliation: Universidad de Santiago de Chile, Facultad de Química y Biología, Departamento de Ciencias del Ambiente, Casilla 40, correo 33, Santiago, Chile. bmodak@lauca.usach.cl
authors.forename: Brenda
authors.initials: B
authors.lastname: Modak
authors.forename: Macarena
authors.initials: M
authors.lastname: Rojas
authors.forename: René
authors.initials: R
authors.lastname: Torres
authors.forename: Jesús
authors.initials: J
authors.lastname: Rodilla
authors.forename: Federico
authors.initials: F
authors.lastname: Luebert
mesh_terms: D000975:Antioxidants / Q000737:chemistry / Q000494:pharmacology*; D052160:Benzothiazoles; D001713:Biphenyl Compounds / Q000737:chemistry; D005609:Free Radicals; D028162:Heliotropium / Q000737:chemistry*; D006834:Hydrazines / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D010851:Picrates; D013451:Sulfonic Acids / Q000737:chemistry; D013844:Thiazoles / Q000737:chemistry
chemical_list: D000975:Antioxidants; D052160:Benzothiazoles; D001713:Biphenyl Compounds; D005609:Free Radicals; D006834:Hydrazines; D010851:Picrates; D013451:Sulfonic Acids; D013844:Thiazoles; C002502:2,2'-azino-di-(3-ethylbenzothiazoline)-6-sulfonic acid; C004931:1,1-diphenyl-2-picrylhydrazyl