[Diffuse large B cell lymphoma presenting with a bilateral serous macular detachment].
METHODS
A 42 year-old male was assessed for a subacute, bilateral and progressive visual loss. His medical history included chronic hepatitis C infection and Evans syndrome. On fundal examination, multiple areas of neurosensorial and retinal pigmented epithelium detachment were observed in the region of both macula. A few days later, his general health deteriorated and he was noted to have a high fever and adenopathy. Biopsy of an enlarged lateral cervical lymph node demonstrated the existence of a diffuse large B cell lymphoma. After several cycles of chemotherapy, he experienced a progressive and bilateral improvement of his vision, which was accompanied by a reattachment of the previously detached areas.


CONCLUSIONS
A bilateral and serous macular detachment may be the initial manifestation of a diffuse large B cell lymphoma. The prognosis of these retinal lesions may be favourable if lymphoma remission is achieved.
Reche-Sainz
J A
JA
Hospital de Fuenlabrada, Madrid, Spain. jalbres@yahoo.es
Peral-Ortiz de la Torre
M J
MJ
Carpio-Bailén
R
R
Toledano-Fernández
N
N
D000328:Adult; D006801:Humans; D016403:Lymphoma, Large B-Cell, Diffuse / Q000150:complications* / Q000175:diagnosis; D008297:Male; D012163:Retinal Detachment / Q000209:etiology*