title: Magnetoencephalographic mapping of interictal spike propagation: a technical and clinical report.
abstract: Distinguishing propagated epileptic activity from primary epileptic foci is of critical importance in presurgical evaluation of patients with medically intractable focal epilepsy. We studied an 11-year-old patient with complex partial epilepsy by using simultaneous magnetoencephalography (MEG) and electroencephalography (EEG). In EEG, bilateral interictal discharges appeared synchronous, whereas MEG source analysis suggested propagation of spikes from the right to the left frontal lobe.
authors.affiliation: MGH/MIT/HMS Athinoula A. Martinos Center for Biomedical Imaging, Charlestown, MA, USA.
authors.forename: K
authors.initials: K
authors.lastname: Hara
authors.forename: F-H
authors.initials: FH
authors.lastname: Lin
authors.forename: S
authors.initials: S
authors.lastname: Camposano
authors.forename: D M
authors.initials: DM
authors.lastname: Foxe
authors.forename: P E
authors.initials: PE
authors.lastname: Grant
authors.forename: B F
authors.initials: BF
authors.lastname: Bourgeois
authors.forename: S P
authors.initials: SP
authors.lastname: Ahlfors
authors.forename: S M
authors.initials: SM
authors.lastname: Stufflebeam
mesh_terms: D000200:Action Potentials; D002648:Child; D003344:Cortical Synchronization; D004569:Electroencephalography; D017029:Epilepsy, Complex Partial / Q000175:diagnosis* / Q000503:physiopathology*; D005260:Female; D005625:Frontal Lobe / Q000503:physiopathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D015225:Magnetoencephalography