title: A case of meningoencephalitis associated with G1P[8] rotavirus infection in a Japanese child.
abstract: We report the case of a 2-y, 11-month-old boy with G1P[8] rotavirus infection accompanied by acute meningoencephalitis. Substitutions in both the VP4 and VP7 genes were found in the identified strain. A commonly circulating G1P[8] rotavirus with such mutations might be associated with the pathogenesis of CNS complications, including meningoencephalitis.
authors.affiliation: Department of Pediatrics, Jichi Medical School, Yakushiji, Shimotsuke, Japan.
authors.forename: Tamako
authors.initials: T
authors.lastname: Goto
authors.forename: Hirokazu
authors.initials: H
authors.lastname: Kimura
authors.forename: Kei
authors.initials: K
authors.lastname: Numazaki
authors.forename: Miho
authors.initials: M
authors.lastname: Akiyama
authors.forename: Masahiko
authors.initials: M
authors.lastname: Kato
authors.forename: Masahiro
authors.initials: M
authors.lastname: Noda
authors.forename: Yasuyuki
authors.initials: Y
authors.lastname: Nozaki
authors.forename: Keiko
authors.initials: K
authors.lastname: Tanaka-Taya
authors.forename: Kiyosu
authors.initials: K
authors.lastname: Taniguchi
authors.forename: Takanori
authors.initials: T
authors.lastname: Yamagata
authors.forename: Osamu
authors.initials: O
authors.lastname: Nishio
authors.forename: Teruko
authors.initials: T
authors.lastname: Oogane
authors.forename: Mariko Y
authors.initials: MY
authors.lastname: Momoi
authors.forename: Nobuhiko
authors.initials: N
authors.lastname: Okabe
mesh_terms: D000212:Acyclovir / Q000627:therapeutic use; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000956:Antigens, Viral / Q000235:genetics; D000998:Antiviral Agents / Q000627:therapeutic use; D044466:Asian People; D036022:Capsid Proteins / Q000235:genetics; D002228:Carbenicillin / Q000627:therapeutic use; D002675:Child, Preschool; D005990:Glycerol / Q000627:therapeutic use; D006801:Humans; D007564:Japan / Q000208:ethnology; D008297:Male; D008587:Meningitis, Viral / Q000175:diagnosis / Q000821:virology*; D010802:Phylogeny; D012401:Rotavirus / Q000145:classification* / Q000235:genetics*; D012400:Rotavirus Infections / Q000821:virology*
chemical_list: D000900:Anti-Bacterial Agents; D000956:Antigens, Viral; D000998:Antiviral Agents; D036022:Capsid Proteins; C060339:VP4 protein, Rotavirus; C050779:VP7 protein, Rotavirus; D002228:Carbenicillin; D005990:Glycerol; D000212:Acyclovir