title: [Therapeutic response to plasmapheresis in four cases with obsessive-compulsive disorder and tic disorder triggered by streptococcal infections].
abstract: The acronym PANDAS (pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections) has been assigned to a subgroup of patients experiencing pediatric onset obsessive-compulsive symptoms and tics as a result of autoimmune response to group A beta-hemolytic streptococcal infection. It has been hypothesized that an immune process initiated by infection affects the basal ganglia and causes neuropsychiatric symptoms. In cases with severe neuropsychiatric symptoms, the use of treatment strategies that interrupt the autoimmune process responsible for the pathogenesis of PANDAS, such as therapeutic plasmapheresis or intravenous immunoglobulin, has been proposed. In this paper, we discuss the effect of plasmapheresis treatment in 4 adult cases of obsessive-compulsive disorder and tic disorder triggered by streptococcal infections.
authors.affiliation: Yüzüncü Yil U Tip Fak., Psikiyatri AD., Van. lbesiroglu@yyu.edu.tr
authors.forename: Lütfullah
authors.initials: L
authors.lastname: Beşiroğlu
authors.forename: Mehmet Yücel
authors.initials: MY
authors.lastname: Ağargün
authors.forename: Ozgür
authors.initials: O
authors.lastname: Ozbebit
authors.forename: Mehmet
authors.initials: M
authors.lastname: Sözen
authors.forename: Imdat
authors.initials: I
authors.lastname: Dilek
authors.forename: Mustafa
authors.initials: M
authors.lastname: Güleç
mesh_terms: D000293:Adolescent; D000328:Adult; D003937:Diagnosis, Differential; D006801:Humans; D008297:Male; D009771:Obsessive-Compulsive Disorder / Q000150:complications / Q000175:diagnosis* / Q000628:therapy; D010956:Plasmapheresis; D013290:Streptococcal Infections / Q000150:complications / Q000175:diagnosis* / Q000628:therapy; D013297:Streptococcus pyogenes; D013981:Tic Disorders / Q000150:complications / Q000175:diagnosis* / Q000628:therapy