title: Prediction of 6-month mortality in nursing home residents with advanced dementia: validity of a risk score.
abstract: OBJECTIVE
  Prognostic information is important for guiding palliative care planning for patients with dementia. We aim to validate a risk score that uses Minimum Data Set (MDS) to estimate 6-month mortality for nursing home residents with advanced dementia.
  
  
  METHODS
  Two cohort studies.
  
  
  METHODS
  Six nursing homes in The Netherlands, and 35 nursing homes in Missouri.
  
  
  METHODS
  Long-term stay residents with advanced dementia: 288 Dutch residents and 269 residents from Missouri who also had a lower respiratory tract infection (LRI).
  
  
  METHODS
  Patient risk factors and 6-month mortality.
  
  
  RESULTS
  Six-month mortality rates were 24.3% for Dutch residents, and 36.8% for US residents. The risk score's AUROC was 0.65 (CI 0.58-0.72), and 0.64 (CI 0.58-0.71), respectively. For the large majority of residents, observed mortality in the 2 validation cohorts were comparable to the development cohort. Among the few residents identified as at very high risk according to the risk score, observed mortality was lower than expected.
  
  
  CONCLUSIONS
  The original mortality risk score predicted 6-month mortality with reasonable accuracy in 2 validation cohorts of nursing home residents with advanced dementia. Thus, the performance of the risk score, at least over the range of low to moderate risk (up to around 40% risk of mortality), can be generalized to long-stay (versus recently admitted) residents with advanced dementia, and to those with LRI.
authors.affiliation: Department of Nursing Home Medicine, EMGO Institute of the VU University Medical Center, Amsterdam, The Netherlands. j.vandersteen@vumc.nl
authors.forename: Jenny T
authors.initials: JT
authors.lastname: van der Steen
authors.forename: Susan L
authors.initials: SL
authors.lastname: Mitchell
authors.forename: Dinnus H M
authors.initials: DH
authors.lastname: Frijters
authors.forename: Robin L
authors.initials: RL
authors.lastname: Kruse
authors.forename: Miel W
authors.initials: MW
authors.lastname: Ribbe
mesh_terms: D000203:Activities of Daily Living; D000368:Aged; D000369:Aged, 80 and over; D003704:Dementia / Q000401:mortality*; D005260:Female; D006304:Health Status; D006801:Humans; D016015:Logistic Models; D008134:Long-Term Care; D008297:Male; D009426:Netherlands; D009735:Nursing Homes; D011379:Prognosis; D012307:Risk Factors; D014481:United States