title: Ovarian reserve in women with polycystic ovary syndrome who underwent laparoscopic ovarian drilling.
abstract: OBJECTIVE
  To evaluate ovarian reserve assessed by hormones and sonography in women with polycystic ovary syndrome (PCOS) undergoing laparoscopic ovarian drilling (LOD).
  
  
  METHODS
  This was a cross-sectional study. Twenty-one PCOS women undergoing LOD were enrolled in the study (the LOD group). Their day-3 anti-Müllerian hormone (AMH), inhibin B, follicle-stimulating hormone (FSH) levels, antral follicles count (AFC) and summed ovarian volume representing ovarian reserve were compared with those of PCOS women who did not undergo LOD (the PCOS group) and those of normal ovulatory women (the control group).
  
  
  RESULTS
  There were no differences in age and body mass index between groups. AMH levels seemed to be lower in the LOD (4.60 +/- 3.16 ng/ml) than in the PCOS (5.99 +/- 3.36 ng/ml) groups, but did not reach statistical significance. Day-3 FSH levels were significantly higher and AFC was significantly lower in the LOD than in the PCOS group. AMH levels, AFC and summed ovarian volume were significantly greater, but FSH was significantly lower, in the PCOS group compared with the control group. There were no differences in inhibin B levels between groups.
  
  
  CONCLUSIONS
  This study showed that ovarian reserve assessed by hormonal levels and sonography seems to be lower in the LOD than in the PCOS group. The PCOS women both with and without LOD had significantly greater ovarian reserve than the age-matched controls having normal ovulatory menstruation.
authors.affiliation: Department of OB-GYN, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand. raswt@mahidol.ac.th
authors.forename: Sawaek
authors.initials: S
authors.lastname: Weerakiet
authors.forename: Srithean
authors.initials: S
authors.lastname: Lertvikool
authors.forename: Yada
authors.initials: Y
authors.lastname: Tingthanatikul
authors.forename: Surapee
authors.initials: S
authors.lastname: Wansumrith
authors.forename: Supatra
authors.initials: S
authors.lastname: Leelaphiwat
authors.forename: Rattiya
authors.initials: R
authors.lastname: Jultanmas
mesh_terms: D000328:Adult; D000367:Age Factors; D000704:Analysis of Variance; D000728:Androgens / Q000097:blood; D054304:Anti-Mullerian Hormone / Q000097:blood; D016009:Chi-Square Distribution; D003430:Cross-Sectional Studies; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D005640:Follicle Stimulating Hormone / Q000097:blood; D006801:Humans; D007265:Inhibins / Q000097:blood; D010535:Laparoscopy; D009929:Organ Size; D010053:Ovary / Q000000981:diagnostic imaging / Q000473:pathology / Q000503:physiopathology*; D010062:Ovulation Induction / Q000009:adverse effects* / Q000379:methods; D011085:Polycystic Ovary Syndrome / Q000097:blood / Q000000981:diagnostic imaging / Q000473:pathology / Q000503:physiopathology* / Q000601:surgery; D016649:Primary Ovarian Insufficiency / Q000097:blood / Q000000981:diagnostic imaging / Q000473:pathology / Q000503:physiopathology; D018709:Statistics, Nonparametric; D014463:Ultrasonography
chemical_list: D000728:Androgens; C422364:inhibin B; D007265:Inhibins; D054304:Anti-Mullerian Hormone; D005640:Follicle Stimulating Hormone