Long-term follow-up of patients with primary immunodeficiencies.
As an example of the need for long-term follow-up by specialty health care to adequately manage immunodeficient patients, we report the case of a patient with Wiskott-Aldrich syndrome who was lost to follow-up for 4 years to the immunology clinic and came back with a neck mass that was diagnosed as B-cell lymphoma. Patients with immunodeficiency are at high risk for the development of malignancy and autoimmune diseases and should be evaluated by a trained specialist with a frequency of not less than every 6 months.
Chinen
Javier
J
Department of Pediatrics, Allergy and Immunology Section, Baylor College of Medicine, Houston, TX 77030, USA. jxchinen@texaschildrenshospital.org
Anmuth
David
D
Franklin
Anna R K
AR
Shearer
William T
WT
D000328:Adult; D005500:Follow-Up Studies; D006801:Humans; D016393:Lymphoma, B-Cell / Q000209:etiology*; D008297:Male; D009333:Neck / Q000473:pathology; D014923:Wiskott-Aldrich Syndrome / Q000150:complications* / Q000276:immunology