Four-stranded coordination helices containing silver-adenine (purine) metallaquartets.
This Communication describes structures of a family of silver-adenine (purine) metallaquartets that occur in a four-stranded coordination motif, bearing a close resemblance to nucleic acid quadruplexes. Using modified purine frameworks, it is further demonstrated that subtle variations in nucleobase heterocycle are tolerable and a metallaquartet is obtained irrespective of the substitution, thus suggesting a high-propensity silver-adenine interaction to achieve quartet structures. All of the solid-state structures studied were orthorhombic, belonging to the Fdd2 space group.
Purohit
Chandra Shekhar
CS
Department of Chemistry, Indian Institute of Technology Kanpur, Kanpur 208016, India.
Mishra
Ashutosh Kumar
AK
Verma
Sandeep
S
D000225:Adenine / Q000737:chemistry*; D001482:Base Composition; D002621:Chemistry / Q000379:methods*; D008670:Metals / Q000737:chemistry; D008968:Molecular Conformation; D015394:Molecular Structure; D011687:Purines / Q000737:chemistry; D012834:Silver / Q000737:chemistry*
D008670:Metals; D011687:Purines; D012834:Silver; D000225:Adenine; C030985:purine