title: Marine amphiphilic siderophores: marinobactin structure, uptake, and microbial partitioning.
abstract: Marinobactins A-E are a suite of amphiphilic siderophores which have a common peptidic head group that coordinates Fe(III), and a fatty acid which varies in length and saturation. As a result of the amphiphilic properties of these siderophores it is difficult to study siderophore-mediated uptake of iron, because the amphiphilic siderophores partition indiscriminately in microbial and other membranes. An alternative method to distinguish amphiphilic siderophore partitioning versus siderophore-mediated active uptake for Fe(III)-marinobactin E has been developed. In addition, a new member of the marinobactin family of siderophores is also reported, marinobactin F, which has a C(18) fatty acid with one double bond and which is substantially more hydrophobic that marinobactins A-E.
authors.affiliation: Department of Chemistry and Biochemistry, University of California, Santa Barbara, CA 93106-9510, USA.
authors.forename: Jennifer S
authors.initials: JS
authors.lastname: Martinez
authors.forename: Alison
authors.initials: A
authors.lastname: Butler
mesh_terms: D002462:Cell Membrane / Q000378:metabolism; D004591:Electrophoresis, Polyacrylamide Gel; D007501:Iron / Q000737:chemistry / Q000378:metabolism; D053520:Marinobacter / Q000378:metabolism; D015394:Molecular Structure; D009842:Oligopeptides / Q000737:chemistry* / Q000378:metabolism / Q000493:pharmacokinetics; D010169:Palmitic Acids / Q000737:chemistry* / Q000378:metabolism / Q000493:pharmacokinetics; D017262:Siderophores / Q000737:chemistry* / Q000378:metabolism / Q000493:pharmacokinetics; D021241:Spectrometry, Mass, Electrospray Ionization
chemical_list: D009842:Oligopeptides; D010169:Palmitic Acids; D017262:Siderophores; C521124:marinobactin E; D007501:Iron