title: In vivo effect of casticin on acute inflammation.
abstract: OBJECTIVE
  To investigate the anti-inflammatory effect of casticin of Fructus Viticis.
  
  
  METHODS
  Observations were made on the anti-inflammatory effect of casticin in the models of acute inflammation in vivo.
  
  
  RESULTS
  Casticin inhibited significantly xylene-induced mouse ear edema, egg albumen-induced rat paw edema and acetic acid-induced mouse vascular permeability.
  
  
  CONCLUSIONS
  Casticin has significant anti-inflammatory effect on acute inflammation, which is probably related to the inhibition of the inflammation factors. Casticin is the effective constituent contributing to the anti-inflammatory effect of Fructus Viticis.
authors.affiliation: Department of Pharmacy, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian Province 350003, China.
authors.forename: Shan
authors.initials: S
authors.lastname: Lin
authors.forename: Hong
authors.initials: H
authors.lastname: Zhang
authors.forename: Ting
authors.initials: T
authors.lastname: Han
authors.forename: Jin-Zhong
authors.initials: JZ
authors.lastname: Wu
authors.forename: Khalid
authors.initials: K
authors.lastname: Rahman
authors.forename: Lu-Ping
authors.initials: LP
authors.lastname: Qin
mesh_terms: D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000494:pharmacology*; D002199:Capillary Permeability / Q000187:drug effects; D004487:Edema / Q000378:metabolism; D005419:Flavonoids / Q000494:pharmacology*; D007249:Inflammation / Q000188:drug therapy* / Q000378:metabolism; D051379:Mice; D008813:Mice, Inbred ICR; D051381:Rats; D017207:Rats, Sprague-Dawley
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D005419:Flavonoids; C054133:casticin