Reduction of aldehydes and ketones by transfer hydrogenation with 1,4-butanediol.
1,4-Butanediol has been used as the hydrogen donor in transfer hydrogenation reactions. The equilibrium is driven by the formation of gamma-butyrolactone, and the diol is therefore not required in excess.
Maytum
Hannah C
HC
Department of Chemistry, University of Bath, Claverton Down, Bath, BA2 7AY, United Kingdom.
Tavassoli
Bahareh
B
Williams
Jonathan M J
JM
D015107:4-Butyrolactone / Q000737:chemistry*; D000447:Aldehydes / Q000737:chemistry*; D002072:Butylene Glycols / Q000737:chemistry*; D020650:Combinatorial Chemistry Techniques; D007659:Ketones / Q000737:chemistry*; D015394:Molecular Structure; D010084:Oxidation-Reduction
D000447:Aldehydes; D002072:Butylene Glycols; D007659:Ketones; C039681:1,4-butanediol; D015107:4-Butyrolactone