title: Preliminary investigation of sensitive biomarkers of trace metal pollution in mussel (Mytilus galloprovincialis) from Izmir Bay (Turkey).
abstract: The aim of this study was to identify possible relationships between biochemical- superoxide dismutase (SOD), glutathione peroxidase (GPx), thiobarbituric acid reactive substances (TBARS) of mussels (Mytilus galloprovincialis) and chemical (Hg, Cd, Pb, Cr, Cu, Zn, Mn and Fe) contaminants from relatively clean area (Middle Bay) and heavily polluted area (Inner Bay) of the Izmir Bay. Sampling of mussels was performed in the beginning of May 2004. Mussel digestive glands have been used for biochemical assays. Trace metal content was determined by atomic absorption spectrophotometer using standard procedures. Metal contents in mussels collected at polluted site increased compared to the middle part of the bay. While there was a positive correlation between metals and SOD enzyme activity, there was a negative correlation between metals and GPx enzyme activity. An increase was observed in SOD enzyme activity and a decrease of GPx enzyme activity at the inner part of the bay.
authors.affiliation: Institute of Marine Sciences and Technology, Inciralti, Dokuz Eylul University, 35340 Izmir, Turkey. filiz.ksezgin@deu.edu.tr
authors.forename: Filiz
authors.initials: F
authors.lastname: Kucuksezgin
authors.forename: B Muammer
authors.initials: BM
authors.lastname: Kayatekin
authors.forename: Esin
authors.initials: E
authors.lastname: Uluturhan
authors.forename: Nazan
authors.initials: N
authors.lastname: Uysal
authors.forename: Osman
authors.initials: O
authors.lastname: Acikgoz
authors.forename: Sevil
authors.initials: S
authors.lastname: Gonenc
mesh_terms: D000818:Animals; D015415:Biomarkers / Q000032:analysis*; D049872:Bivalvia / Q000201:enzymology; D005979:Glutathione Peroxidase / Q000378:metabolism; D019216:Metals, Heavy / Q000032:analysis*; D012680:Sensitivity and Specificity; D013482:Superoxide Dismutase / Q000378:metabolism; D014131:Trace Elements / Q000032:analysis*; D014421:Turkey; D014874:Water Pollutants, Chemical / Q000032:analysis*
chemical_list: D015415:Biomarkers; D019216:Metals, Heavy; D014131:Trace Elements; D014874:Water Pollutants, Chemical; D005979:Glutathione Peroxidase; D013482:Superoxide Dismutase