title: Cessation of nail growth following Bajiaolian intoxication.
abstract: Bajiaolian (Dysosma pleianthum), a species in the Mayapple family (Podophyllum pelatum), has been widely used as a traditional Chinese herbal medication for the remedies of snake bite, tumor growth, post-partum recovery, and acne. It has also been used in western medicine, especially topically for various skin lesions. Both oral ingestion and dermal application may result in severe toxicity. The clinical presentations reported after Bajiaolian poisoning include nausea, vomiting, diarrhea, abdominal cramps, tachycardia, orthostatic hypotension, paralytic ileus, urinary retention, hepatorenal dysfunction, leukocytosis followed by leukopenia, thrombocytopenia, prolonged areflexia, prolonged paraethesia and sensory ataxia, dizziness, fever, memory impairment, hallucinations, paranoia, convulsion, fainting, and coma. There are no previous reports in the literature about the cessation of nail growth as a clinical presentation following Bajiaolian poisoning. We present a case of nail growth that was halted for more than seven years after a single case of Bajiaolian poisoning.
authors.affiliation: Department of Emergency Medicine, Taipei Veterans Hospital, Taipei, Taiwan, Republic of China.
authors.forename: Shang-Lin
authors.initials: SL
authors.lastname: Chou
authors.forename: Ming-Yueh
authors.initials: MY
authors.lastname: Chou
authors.forename: Wei-Fong
authors.initials: WF
authors.lastname: Kao
authors.forename: David H T
authors.initials: DH
authors.lastname: Yen
authors.forename: Chun-I
authors.initials: CI
authors.lastname: Huang
authors.forename: Chen-Hsen
authors.initials: CH
authors.lastname: Lee
mesh_terms: D000328:Adult; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000506:poisoning* / Q000627:therapeutic use; D005260:Female; D006261:Headache / Q000188:drug therapy; D006801:Humans; D009260:Nail Diseases / Q000139:chemically induced / Q000473:pathology; D009262:Nails / Q000187:drug effects* / Q000254:growth & development; D028144:Podophyllum peltatum / Q000737:chemistry*
chemical_list: D004365:Drugs, Chinese Herbal