title: Quantum-chemical descriptors for estimating hemolytic activity of aliphatic and aromatic methacrylates.
abstract: Methacrylates such as methyl methacrylate (6), triethyleneglycol dimethacrylate (5) and bisphenol A glycidyldimethacrylate, bis-GMA, (8) are widely used as materials in dental resins perturbation of the phosphatidylcholine-cholesterol interaction. Such effects of aromatic methacrylates may be involved in their marked hemolytic action.
authors.affiliation: Division of Chemistry, Meikai University School of Dentistry, 1-1 Keyakidai, Sakado, Saitama 350-0283, Japan.
authors.forename: Mariko
authors.initials: M
authors.lastname: Ishihara
authors.forename: Seiichiro
authors.initials: S
authors.lastname: Fujisawa
mesh_terms: D000818:Animals; D004285:Dogs; D006461:Hemolysis / Q000187:drug effects*; D008689:Methacrylates / Q000737:chemistry* / Q000633:toxicity*; D021281:Quantitative Structure-Activity Relationship; D012117:Resins, Synthetic / Q000737:chemistry / Q000633:toxicity
chemical_list: D008689:Methacrylates; D012117:Resins, Synthetic