Identifying and targeting hypoxia in head and neck cancer: a brief overview of current approaches.
Le
Quynh-Thu
QT
Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA 94305, USA. qle@stanford.edu
D000951:Antigens, Neoplasm / Q000032:analysis; D015415:Biomarkers / Q000032:analysis; D000071231:Carbonic Anhydrase IX; D002256:Carbonic Anhydrases / Q000032:analysis; D002294:Carcinoma, Squamous Cell / Q000503:physiopathology*; D015687:Cell Hypoxia / Q000187:drug effects / Q000502:physiology; D004566:Electrodes; D017341:Etanidazole / Q000008:administration & dosage / Q000031:analogs & derivatives / Q000378:metabolism; D006258:Head and Neck Neoplasms / Q000503:physiopathology* / Q000532:radiotherapy; D006801:Humans; D006845:Hydrocarbons, Fluorinated / Q000008:administration & dosage / Q000378:metabolism; D047908:Intracellular Signaling Peptides and Proteins; D024101:Mitochondrial Proteins; D009363:Neoplasm Proteins / Q000032:analysis; D009593:Nitroimidazoles / Q000008:administration & dosage / Q000378:metabolism; D053495:Osteopontin / Q000097:blood; D010100:Oxygen / Q000032:analysis / Q000378:metabolism / Q000627:therapeutic use; D010313:Partial Pressure; D011838:Radiation-Sensitizing Agents / Q000627:therapeutic use; D000077704:Tirapazamine; D014227:Triazines / Q000627:therapeutic use; D005466:Fluorocarbons
D000951:Antigens, Neoplasm; D015415:Biomarkers; D000071231:Carbonic Anhydrase IX; D002256:Carbonic Anhydrases; D017341:Etanidazole; D006845:Hydrocarbons, Fluorinated; D047908:Intracellular Signaling Peptides and Proteins; D024101:Mitochondrial Proteins; D009363:Neoplasm Proteins; D009593:Nitroimidazoles; D053495:Osteopontin; D010100:Oxygen; D011838:Radiation-Sensitizing Agents; D000077704:Tirapazamine; D014227:Triazines; C405619:HIGD1A protein, human; C096011:2-(2-nitro-1H-imidazol-1-yl)-N-(2,2,3,3,3-pentafluoropropyl)acetamide; D005466:Fluorocarbons; C033815:pimonidazole; C089226:CA9 protein, human