title: Selective palliative transcatheter embolization of bony metastases from renal cell carcinoma.
abstract: To examine whether transcatheter embolization of bone metastases is an effective palliative option for patients with renal cell carcinoma (RCCa). A retrospective review of 21 patients presenting for palliative embolization of painful RCCa skeletal metastases was performed. Details regarding anatomic sites, procedural details, and embolization materials were collected. The clinical response of the patient was assessed from clinic visits and analgesic use. Thirty separate embolization procedures were used to treat 39 metastatic lesions (18 pelvic, 8 lower extremity, 3 upper extremity, 5 rib/chest well, and 5 vertebral lesions). Five patients underwent more than one embolization. Polyvinyl alcohol was used in all 30 embolization procedures. Additional embolic materials were used in 16 of 30 procedures. A clinical response was achieved at 36 treated sites; the mean duration fo the response was 5.5 months. Selective embolization of bony renal cell carcinoma metastases can provide effective palliation in a patient population which has limited therapeutic options.
authors.affiliation: Division of Vascular/Interventional Radiology, University of Michigan Medical Center, Ann Arbor, Michigan 48109, USA. andrew.r.forauer@hitchcock.org
authors.forename: Andrew R
authors.initials: AR
authors.lastname: Forauer
authors.forename: Elizabeth
authors.initials: E
authors.lastname: Kent
authors.forename: Wojciech
authors.initials: W
authors.lastname: Cwikiel
authors.forename: Peggy
authors.initials: P
authors.lastname: Esper
authors.forename: Bruce
authors.initials: B
authors.lastname: Redman
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000792:Angiography; D001859:Bone Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary / Q000628:therapy*; D002292:Carcinoma, Renal Cell / Q000556:secondary*; D002404:Catheterization; D004621:Embolization, Therapeutic / Q000379:methods*; D005260:Female; D006801:Humans; D007680:Kidney Neoplasms / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D010166:Palliative Care / Q000379:methods*; D011142:Polyvinyl Alcohol / Q000008:administration & dosage; D012189:Retrospective Studies
chemical_list: D011142:Polyvinyl Alcohol