title: Complicated skin and soft-tissue infections: diagnostic approach and empiric treatment options.
abstract: Skin and soft-tissue infections are common and generally are uncomplicated at the time of initial presentation. However, these infections can worsen quickly when there are delays in presentation and treatment. Upon encountering these infections, physicians must respond quickly with an appropriate therapeutic plan and be aware of trends in microbial resistance in order to optimize patient care.
authors.affiliation: Department of Surgery, MetroHealth Medical Center, Cleveland, OH 44109-1998, USA.
authors.forename: James I
authors.initials: JI
authors.lastname: Merlino
authors.forename: Mark A
authors.initials: MA
authors.lastname: Malangoni
mesh_terms: D000890:Anti-Infective Agents / Q000494:pharmacology / Q000627:therapeutic use*; D017714:Community-Acquired Infections / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology / Q000382:microbiology; D042241:Early Diagnosis; D006801:Humans; D016106:Methicillin Resistance; D011320:Primary Health Care / Q000379:methods*; D012874:Skin Diseases, Infectious / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology / Q000382:microbiology; D018461:Soft Tissue Infections / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology / Q000382:microbiology; D013211:Staphylococcus aureus / Q000187:drug effects / Q000302:isolation & purification
chemical_list: D000890:Anti-Infective Agents