title: Association of macroamylasemia and type I macro-creatine kinasemia. A case report.
abstract: BACKGROUND
  Macroenzymes are serum enzymes presenting a higher molecular mass than the corresponding enzymes normally found in physiologic conditions or specific diseases, causing falsely increased total serum enzyme levels. The occurrence of macroenzymes represents a rare event in clinical practice, leading to unnecessary and often invasive additional diagnostic procedures. Macroamylase and macro-creatine kinase belong to this category and may generate diagnostic confusion in the differential diagnosis between acute pancreatitis and acute myocardial infarction. Until now, the association of macroamylase and macro-creatine kinase in the same patient has never been described.
  
  
  METHODS
  A 68-year-old female patient presenting with increased serum levels of creatinine kinase and amylase at admission.
  
  
  CONCLUSIONS
  This article reports the association of macroamylase and macro-creatine kinase in the same patient for the first time.
authors.affiliation: Internal Medicine Unit III, General Medicine Department, Cardarelli Hospital, Naples, Italy.
authors.forename: Fernando
authors.initials: F
authors.lastname: Gallucci
authors.forename: Elisa
authors.initials: E
authors.lastname: Madrid
authors.forename: Pasquale
authors.initials: P
authors.lastname: Esposito
authors.forename: Generoso
authors.initials: G
authors.lastname: Uomo
mesh_terms: D000368:Aged; D000681:Amylases / Q000097:blood*; D003402:Creatine Kinase / Q000032:analysis / Q000097:blood*; D004587:Electrophoresis, Agar Gel; D005260:Female; D006801:Humans; D034321:Hyperamylasemia / Q000097:blood* / Q000145:classification / Q000175:diagnosis*
chemical_list: D003402:Creatine Kinase; D000681:Amylases; C001663:macroamylase