title: [Clinical assessment of selected vascularization attributes of adnexal masses in preoperative prediction of tumor malignancy].
abstract: BACKGROUND
  Preoperative differential diagnosis of adnexal masses has been a challenge for researchers for years. Prediction of tumor malignancy is essential for selection of optimal treatment with lowest risk for patient. Assessment of various tumor vascularization attributes, using color Doppler semi-quantitative analysis, can be helpful for malignancy differentiation.
  
  
  OBJECTIVE
  To assess value of selected vascularization attributes of adnexal masses in preoperative prediction of tumor malignancy.
  
  
  METHODS
  This study included 521 women diagnosed and treated for adnexal masses (181 malignant and 340 benign) in Obstetrics and Gynecology Hospital of University of Medical Sciences in Poznan between 1994 and 2004. All of them underwent color Doppler examination using Aloka 2000 and 5500 devices (vaginal probes 5,0-6,5 MHz, abdominal probes 3,5-5 MHz) with evaluation of such attributes as: vessels count, localization and structure; semi-quantitative scale was also constructed basing on these parameters.
  
  
  RESULTS
  There was a significantly higher number of vessels (cut-off value=4; p < 0.0001), central vessels localization (p < 0.0001) and irregular structure of vessels (p < 0.0001) in patients with confirmed malignant tumor. Constructed semi-quantitative Doppler scale resulted in highest diagnostic accuracy (cut-off value = 3; p < 0.0001).
  
  
  CONCLUSIONS
  Central vessels localization was the single most significant attribute in tumor malignancy differentiation. Constructed semi-quantitative Doppler scale resulted in highest diagnostic accuracy and can be a useful tool in preoperative prediction of tumormalignancy.
authors.affiliation: Klinika Ginekologii Operacyjnej, Ginekologiczno-Połoaniczy Szpital Kliniczny Uniwersytetu Medycznego im. Karola Marcinkowskiego w Poznaniu. kamila.witczak@gmail.com
authors.forename: Kamila
authors.initials: K
authors.lastname: Witczak
authors.forename: Dariusz
authors.initials: D
authors.lastname: Szpurek
authors.forename: Rafał
authors.initials: R
authors.lastname: Moszyński
authors.forename: Łukasz
authors.initials: Ł
authors.lastname: Sroka
authors.forename: Stefan
authors.initials: S
authors.lastname: Sajdak
mesh_terms: D000328:Adult; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008875:Middle Aged; D009367:Neoplasm Staging; D009389:Neovascularization, Pathologic / Q000000981:diagnostic imaging*; D010049:Ovarian Diseases / Q000097:blood / Q000000981:diagnostic imaging; D010051:Ovarian Neoplasms / Q000098:blood supply* / Q000000981:diagnostic imaging*; D010053:Ovary / Q000098:blood supply* / Q000000981:diagnostic imaging; D011044:Poland; D011237:Predictive Value of Tests; D012372:ROC Curve; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D018615:Ultrasonography, Doppler, Color