title: [Semen cryopreservation for patients with malignant or non-malignant disease: our 14-year experience].
abstract: We retrospectively analyzed 163 patients who had been cryopreservating their sperm one year or more. They consisted of 72, 76 and 15 patients with a germ cell tumor, hematologic cancer and other diseases, respectively. Forty-eight patients (29.4%) were still cryoperservating their sperm, and the average period of cryoperservation was 4.7 +/- 3.0 years (1-13.1 years). Only 6 patients (3.7%) had used their cryopreserved sperm and the average preserved period was 6.0 years (1.3-12 years). In 115 of the 163 cases, the cryopreserved sperm was abandoned, and the main reason was the recovery of spermatogenesis. Of the cases that underwent semen analysis after treatment, 20.9% of the patients with testicular cancer and 57.9% of the patients with hematologic cancer, have not recovered spermatogenesis. Because chemotherapy to the testicular tumor and leukemia risk injuring testiclar function, cryopreservation of the sperm before treatment should be recommended. Because the preservation period tends to be prolonged, development of a system for long-time preservation is awaited.
authors.affiliation: Department of Urology, Ohguchi Higashi General Hospital.
authors.forename: Kotaro
authors.initials: K
authors.lastname: Suzuki
authors.forename: Junichi
authors.initials: J
authors.lastname: Matuzaki
authors.forename: Yusuke
authors.initials: Y
authors.lastname: Hattori
authors.forename: Kazuo
authors.initials: K
authors.lastname: Saito
authors.forename: Kazumi
authors.initials: K
authors.lastname: Noguchi
authors.forename: Yasushi
authors.initials: Y
authors.lastname: Yumura
authors.forename: Kazuhiko
authors.initials: K
authors.lastname: Sato
authors.forename: Akira
authors.initials: A
authors.lastname: Iwasaki
authors.forename: Yoshinobu
authors.initials: Y
authors.lastname: Kubota
mesh_terms: D000328:Adult; D015925:Cryopreservation / Q000706:statistics & numerical data*; D006801:Humans; D007248:Infertility, Male / Q000628:therapy*; D007938:Leukemia / Q000628:therapy; D008297:Male; D010307:Parotid Neoplasms / Q000628:therapy; D027724:Reproductive Techniques, Assisted; D012189:Retrospective Studies; D012662:Semen Preservation / Q000706:statistics & numerical data*; D013076:Sperm Count; D013736:Testicular Neoplasms / Q000628:therapy; D013997:Time Factors