Complex partial status epilepticus in paraneoplastic limbic encephalitis.
Paraneoplastic limbic encephalitis (PLE) results from tumor-related autoimmune mediated inflammation and degeneration of the mesial temporal structures. Cognitive and behavioral changes and seizures occur in PLE. Seizures are an uncommon presenting symptom of PLE occurring in 6 of 50 patients in one series. We present a report of complex partial status epilepticus (CPSE) as the presentation of PLE with anti-neuronal antibodies and improvement in mental status following treatment of seizures.
Kile
S J
SJ
Department of Neurology, University of California-Davis Medical Center, California, USA. shawn.kile@ucdmc.ucdavis.edu
Kim
J C
JC
Seyal
M
M
D002289:Carcinoma, Non-Small-Cell Lung / Q000150:complications* / Q000175:diagnosis* / Q000503:physiopathology / Q000628:therapy; D003131:Combined Modality Therapy; D003937:Diagnosis, Differential; D004569:Electroencephalography; D005260:Female; D006801:Humans; D020363:Limbic Encephalitis / Q000175:diagnosis* / Q000209:etiology* / Q000503:physiopathology / Q000628:therapy; D008175:Lung Neoplasms / Q000150:complications* / Q000175:diagnosis* / Q000503:physiopathology / Q000628:therapy; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D013226:Status Epilepticus / Q000175:diagnosis* / Q000209:etiology* / Q000503:physiopathology / Q000628:therapy; D014055:Tomography, Emission-Computed; D014057:Tomography, X-Ray Computed