Association of macroamylasemia and type I macro-creatine kinasemia. A case report.
BACKGROUND
Macroenzymes are serum enzymes presenting a higher molecular mass than the corresponding enzymes normally found in physiologic conditions or specific diseases, causing falsely increased total serum enzyme levels. The occurrence of macroenzymes represents a rare event in clinical practice, leading to unnecessary and often invasive additional diagnostic procedures. Macroamylase and macro-creatine kinase belong to this category and may generate diagnostic confusion in the differential diagnosis between acute pancreatitis and acute myocardial infarction. Until now, the association of macroamylase and macro-creatine kinase in the same patient has never been described.


METHODS
A 68-year-old female patient presenting with increased serum levels of creatinine kinase and amylase at admission.


CONCLUSIONS
This article reports the association of macroamylase and macro-creatine kinase in the same patient for the first time.
Gallucci
Fernando
F
Internal Medicine Unit III, General Medicine Department, Cardarelli Hospital, Naples, Italy.
Madrid
Elisa
E
Esposito
Pasquale
P
Uomo
Generoso
G
D000368:Aged; D000681:Amylases / Q000097:blood*; D003402:Creatine Kinase / Q000032:analysis / Q000097:blood*; D004587:Electrophoresis, Agar Gel; D005260:Female; D006801:Humans; D034321:Hyperamylasemia / Q000097:blood* / Q000145:classification / Q000175:diagnosis*
D003402:Creatine Kinase; D000681:Amylases; C001663:macroamylase