title: Syntheses and biological activities of 6-aryl-3-(3-hydroxypropyl)-7H-1,2,4-triazolo[3,4-b][1,3,4]thiadiazines.
abstract: A series of 6-aryl-3-(3-hydroxypropyl)-7H-1,2,4-triazolo[3,4-b][1,3,4]-thiadiazines were synthesized by the reaction of 4-amino-3-(3-hydroxypropyl)-5-mercapto-1,2,4-triazole (1) with substituted omega-haloacetophenones. Their structures were confirmed by elemental analysis, IR, 1H-NMR, and 13C-NMR. Tests of plant growth regulating effects showed that the title compounds display remarkable inhibitory activities on the growth of radish and wheat.
authors.affiliation: College of Education, Wenzhou University, Wenzhou 325035, P.R. China.
authors.forename: Jian-yu
authors.initials: JY
authors.lastname: Jin
authors.forename: Li-xue
authors.initials: LX
authors.lastname: Zhang
authors.forename: Xian-xing
authors.initials: XX
authors.lastname: Chen
authors.forename: An-jiang
authors.initials: AJ
authors.lastname: Zhang
authors.forename: Hai-le
authors.initials: HL
authors.lastname: Zhang
mesh_terms: D002247:Carbon Isotopes; D018525:Germination / Q000187:drug effects; D009682:Magnetic Resonance Spectroscopy; D010937:Plant Growth Regulators / Q000494:pharmacology; D018517:Plant Roots / Q000187:drug effects; D018520:Plant Shoots / Q000187:drug effects; D031224:Raphanus / Q000187:drug effects; D013055:Spectrophotometry, Infrared; D013829:Thiadiazines / Q000138:chemical synthesis* / Q000737:chemistry / Q000378:metabolism* / Q000494:pharmacology; D014230:Triazoles / Q000138:chemical synthesis* / Q000737:chemistry / Q000378:metabolism* / Q000494:pharmacology; D014908:Triticum / Q000187:drug effects
chemical_list: D002247:Carbon Isotopes; D010937:Plant Growth Regulators; D013829:Thiadiazines; D014230:Triazoles