title: [Diabetes insipidus revealing chronic myelomonocytic leukemia].
abstract: BACKGROUND
  Central diabetes insipidus is most frequently reported to occur after a trauma from surgery or accident. However, between 30 and 50% of cases are considered idiopathic. It's a rare complication of myelodysplastic syndrome.
  
  
  METHODS
  A 61-year-old patient presented central diabetes insipidus revealing, 17 months before, chronic myelomonocytic leukemia. Cytogenetics studies revealed monosomy 7. Acute myeloid leukemia appears 3 months after training rapid patient's death.
  
  
  CONCLUSIONS
  Blood examination is necessary before to conclude idiopathic central diabetes insipidus. The discovery of chronic myelomonocytic leukemia implicates a rapid managing before its possible acute myeloid leukemia transformation. Indeed, prognosis of central diabetes insipidus and acute myeloid leukemia associated, in presence of monosomy 7, is very poor.
authors.affiliation: Service de médecine interne, HIA Sainte-Anne, 83800 Toulon-Armées, France. graffin-bruno@noos.fr
authors.forename: B
authors.initials: B
authors.lastname: Graffin
authors.forename: P
authors.initials: P
authors.lastname: Bernard
authors.forename: C
authors.initials: C
authors.lastname: Landais
authors.forename: O
authors.initials: O
authors.lastname: Gisserot
authors.forename: M
authors.initials: M
authors.lastname: Aletti
authors.forename: G
authors.initials: G
authors.lastname: Leyral
authors.forename: J-F
authors.initials: JF
authors.lastname: Paris
authors.forename: P
authors.initials: P
authors.lastname: Carli
mesh_terms: D002897:Chromosomes, Human, Pair 7 / Q000235:genetics; D003919:Diabetes Insipidus / Q000175:diagnosis*; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000175:diagnosis; D015477:Leukemia, Myelomonocytic, Chronic / Q000175:diagnosis*; D008297:Male; D008875:Middle Aged; D009006:Monosomy / Q000175:diagnosis / Q000235:genetics