title: Subjective cognitive dysfunction associated with drug-induced parkinsonism in schizophrenia.
abstract: The authors investigated the subjective cognitive dysfunction associated with drug-induced parkinsonism (DIP) among 58 stabilized schizophrenic outpatients. Subjective cognitive dysfunction was comprehensively assessed using the Frankfurt Complaint Questionnaire (FCQ). Multivariate analysis revealed that the DIP group scored significantly higher on the total FCQ score than the non-DIP group. In phenomenological subscale scores, the DIP group had significantly higher scores on "deterioration of discrimination", "psychomotor disorder", and "perceptual disorder" than the non-DIP group. These results suggest that DIP is significantly associated with subjective cognitive-perceptual dysfunction, reflecting the complex nature of DIP that includes motor and cognitive aspects.
authors.affiliation: Department of Psychiatry, Gil Medical Center, Gachon University of Medicine and Science, 1198 Guwol-Dong, Namdong-Gu, Incheon 405-760, Korea. jhnp@chol.com
authors.forename: Jong-Hoon
authors.initials: JH
authors.lastname: Kim
authors.forename: Seong-Youn
authors.initials: SY
authors.lastname: Kim
authors.forename: Hee-Jung
authors.initials: HJ
authors.lastname: Byun
mesh_terms: D000328:Adult; D014150:Antipsychotic Agents / Q000009:adverse effects*; D003072:Cognition Disorders / Q000150:complications*; D005260:Female; D006801:Humans; D008297:Male; D015999:Multivariate Analysis; D009483:Neuropsychological Tests; D020734:Parkinsonian Disorders / Q000139:chemically induced* / Q000150:complications*; D012559:Schizophrenia / Q000188:drug therapy; D012720:Severity of Illness Index; D011795:Surveys and Questionnaires
chemical_list: D014150:Antipsychotic Agents