title: A 25-year follow-up of a population screened with faecal occult blood test in Finland.
abstract: The aim of the study was to assess the feasibility of and possible selection to attend in colorectal cancer screening.
  
  
  METHODS
  During the years 1979-1980, 1 785 men and women (born in 1917-1929) were invited to a pilot screening project for colorectal cancer. The screening method used was a guaiac-based faecal occult blood test repeated once if the initial test was positive.
  
  
  RESULTS
  Compliance was 69% and the test was positive in 19% of those attending. In a record linkage with the Finnish Cancer Registry, 47 colorectal cancer cases and 24 deaths from colorectal cancer were observed by the end of 2004. In all, the particular test method was not regarded specific enough for population screening. There was, however, no difference in cancer incidence between those who complied and those who did not when compared to the general population of same age and gender.
  
  
  CONCLUSIONS
  Compliance was found high enough to make screening feasible and there was no self selection of persons with low cancer risk to attend screening.
authors.affiliation: Finnish Cancer Registry, Institute for Statistical and Epidemiological Cancer Research, Liisankatu 21 B, FI-001 70 Helsinki, Finland. nea.malila@cancer.fi
authors.forename: Nea
authors.initials: N
authors.lastname: Malila
authors.forename: Matti
authors.initials: M
authors.lastname: Hakama
authors.forename: Eero
authors.initials: E
authors.lastname: Pukkala
mesh_terms: D015331:Cohort Studies; D015179:Colorectal Neoplasms / Q000175:diagnosis* / Q000453:epidemiology / Q000401:mortality; D005240:Feasibility Studies; D005260:Female; D005387:Finland; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D008297:Male; D008403:Mass Screening / Q000379:methods*; D009780:Occult Blood; D010349:Patient Compliance; D011933:Reagent Kits, Diagnostic; D012680:Sensitivity and Specificity
chemical_list: D011933:Reagent Kits, Diagnostic