[Photoaging of a skin].
Photoaging is a skin aging caused by long-term exposure to the ultraviolet radiations of the sun. Ultraviolet activates activating protein-1 and generate reactive oxygen species which play a substantial role in collagen degradation. Clinically, photoaged skin appears as a coarse with deep wrinkles. Presently there are available several agents to reverse the photodamage. There is conclusive evidence that synthetic vitamin A derivatives are the most effective in the treatment of photoaging. Erythema and scaling may be experienced initially.
Galus
Ryszard
R
Akademia Medyczna w Warszawie, Katedra i Zakład Histologii i Embriologii Centrum Biostruktury. rgalus@ib.amwaw.edu.pl
Zandecki
Łukasz
Ł
Antiszko
Marek
M
Borowska
Katarzyna
K
Zabielski
Stanisław
S
D000818:Animals; D006801:Humans; D012867:Skin / Q000528:radiation effects*; D015595:Skin Aging / Q000187:drug effects; D014466:Ultraviolet Rays / Q000009:adverse effects*; D014801:Vitamin A / Q000494:pharmacology
D014801:Vitamin A