[Updates on gemcitabine on metastatic breast cancer].
Gemcitabine is one of the key products actually used in metastatic breast cancer. Thanks to its favourable toxicity profile, gemcitabine can be used in combination with a number of drugs. Recently published and presented results from different trials may modify our perception and strategies regarding metastatic breast cancer. In this overview we will focus on the results of these trials and particularly those recent concerning the combination of gemcitabine with taxanes, vinorelbine, platinum salts and trastuzumab.
Gligorov
Joseph
J
Service d'oncologie médicale, hôpital Tenon, Cancer Est. joseph.gligorov@tnn.aphp.fr
Selle
Fréderic
F
Khalil
Ahmed
A
Abbas
Faddi
F
Namer
Moïse
M
Lotz
Jean-Pierre
JP
D000911:Antibodies, Monoclonal / Q000008:administration & dosage; D061067:Antibodies, Monoclonal, Humanized; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001943:Breast Neoplasms / Q000188:drug therapy* / Q000473:pathology; D017322:Clinical Trials, Phase II as Topic; D017326:Clinical Trials, Phase III as Topic; D003841:Deoxycytidine / Q000008:administration & dosage / Q000031:analogs & derivatives*; D005260:Female; D006801:Humans; D009944:Organoplatinum Compounds / Q000008:administration & dosage / Q000009:adverse effects; D000077150:Oxaliplatin; D017239:Paclitaxel / Q000008:administration & dosage / Q000009:adverse effects; D000068878:Trastuzumab; D014747:Vinblastine / Q000008:administration & dosage / Q000009:adverse effects / Q000031:analogs & derivatives; D000077235:Vinorelbine; D000093542:Gemcitabine
D000911:Antibodies, Monoclonal; D061067:Antibodies, Monoclonal, Humanized; D009944:Organoplatinum Compounds; D000077150:Oxaliplatin; D003841:Deoxycytidine; D014747:Vinblastine; D000068878:Trastuzumab; D017239:Paclitaxel; D000077235:Vinorelbine; D000093542:Gemcitabine