Cyclic nucleotide-regulated ion channels: spotlight on symmetry.
In this issue of Structure, Chiu et al. (2007) report the 16 A EM structure of the prokaryotic cyclic nucleotide-regulated K(+) channel MloK1. This structure reveals that the channel is arranged as a four-fold symmetric tetramer.
Taraska
Justin W
JW
Zagotta
William N
WN
D018360:Crystallography, X-Ray; D007473:Ion Channels / Q000737:chemistry / Q000502:physiology*; D009712:Nucleotides, Cyclic / Q000502:physiology*; D011487:Protein Conformation
D007473:Ion Channels; D009712:Nucleotides, Cyclic