Documented transient third-degree atrioventricular block and asystole in a child with familial dysautonomia.
An 11-year-old boy with familial dysautonomia presented with palpitations. Continuous 24-h Holter monitoring revealed intermittent high-grade atrioventricular block and asystole. The unopposed parasympathetic tone in patients with dysautonomia may make them susceptible to bradycardia and atrioventricular block. We recommend routine 24-h Holter monitoring screening and, when indicated, consideration of pacemaker implantation to reduce the high risk of sudden death phenomena in this patient population.
Rotstein
Amichay
A
Division of Pediatric Cardiology, Schneider Children's Medical Center of Israel, Petah Tikva, and Sackler Faculty of Medicine, Tel Aviv University, 14 Kaplan Street, Petah-Tikva 49202, Israel. amichay@clalit.org.il
Charrow
Joel
J
Deal
Barbara J
BJ
D054537:Atrioventricular Block / Q000175:diagnosis / Q000209:etiology* / Q000503:physiopathology; D002648:Child; D004402:Dysautonomia, Familial / Q000150:complications* / Q000503:physiopathology; D004562:Electrocardiography; D015716:Electrocardiography, Ambulatory; D006323:Heart Arrest / Q000175:diagnosis / Q000209:etiology* / Q000503:physiopathology; D006801:Humans; D008297:Male