title: Intravenous gammaglobulin-induced chronic renal failure in a patient with multiple myeloma.
abstract: Although generally well tolerated there have been a number of reports of acute deterioration in renal function with the use of intravenous immune globulin (IVIG). It is of generally limited duration and is self-limiting. We for the first time have described a patient with multiple myeloma and normal renal function who developed chronic renal failure shortly after IVIG treatment in a patient with no pre-existing renal disease. We would therefore recommend the cautious use of IVIG in patients with normal renal function or with pre-existing renal disease. Renal function should also be assessed both prior to and after application of IVIG.
authors.affiliation: Department of Medical Oncology, School of Medicine, Gaziantep University, Gaziantep Oncology Hospital, Gaziantep 27310, Turkey. sevinc@gantep.edu.tr
authors.forename: Alper
authors.initials: A
authors.lastname: Sevinc
authors.forename: Celalettin
authors.initials: C
authors.lastname: Camci
authors.forename: Suleyman
authors.initials: S
authors.lastname: Buyukberber
authors.forename: Bulent
authors.initials: B
authors.lastname: Akgul
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000009:adverse effects*; D007167:Immunotherapy / Q000009:adverse effects; D007676:Kidney Failure, Chronic / Q000139:chemically induced* / Q000150:complications / Q000628:therapy; D008297:Male; D008875:Middle Aged; D009101:Multiple Myeloma / Q000150:complications / Q000188:drug therapy*; D016896:Treatment Outcome
chemical_list: D016756:Immunoglobulins, Intravenous