Atypical thymic carcinoid in multiple endocrine neoplasia type 1 syndrome.
An asymptomatic, non-smoker patient carrier of a multiple endocrine neoplasia syndrome type 1 (MEN1) mutation was diagnosed with invasive atypical thymic carcinoid tumor. After surgical treatment the tumor reappeared albeit without metastasis. Thymic carcinoid is a well-known cause of mortality in MEN1, and usually metastatic disease is present at diagnosis. Male sex, smoking, and previous hyperparathyroidism probably play a role in the pathogenesis of this neoplasia.
Vidal
A
A
Department of Endocrinology, Hospital Juan Canalejo, 15006 A Coruña, Spain. avcyo@mixmail.com
Lorenzo
M J
MJ
Isidro
M L
ML
Cordido
F
F
D000328:Adult; D002276:Carcinoid Tumor / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D006801:Humans; D008175:Lung Neoplasms / Q000556:secondary / Q000601:surgery; D008297:Male; D018761:Multiple Endocrine Neoplasia Type 1 / Q000150:complications*; D010496:Pericardium / Q000473:pathology; D013953:Thymus Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery