title: [Rational approach to the management of IV stage gastric carcinoma with hepatic metastasis].
abstract: OBJECTIVE
  To investigate the benefit of surgical resection on the prognosis of patients with advanced gastric carcinoma and liver metastasis.
  
  
  METHODS
  Data of 102 cases of advanced gastric carcinoma with liver metastases from 1993 to 2004 were studied retrospectively.
  
  
  RESULTS
  The half-, one- and two-year postoperative survival rates of gastric carcinoma patients with H(1) metastasis undergone palliative resections were 69%, 44% and 6% respectively, which were significantly better than those of patients not undergone resection(accepted by-pass procedure or exploratory laparotomy) (P=0.009). The half-, one- and two-year postoperative survival rates of gastric carcinoma patients with H(2) metastasis undergone palliative resections were 56%,13% and 6% respectively, which were not significantly different compared with those of patients not undergone resection(P=0.068). The half-, one- and two-year postoperative survival rates of gastric carcinoma patients with H(3) metastasis undergone palliative resections were 25%, 13% and 0, which were not significantly different compared with those of cases not undergone resection (P=0.157). Regardless of peritoneal metastases, there were no significant differences between the survival rate of resection group and that of non-resection group.
  
  
  CONCLUSIONS
  Gastric carcinoma patients with H(1) metastasis would benefit from palliative resection regardless of peritoneal metastasis. Gastric carcinoma patients with H(2) or H(3) metastasis are not benefit from surgical resection.
authors.affiliation: Department of Oncology, The First Affiliated Hospital, China Medial University, Shenyang 110001, China.
authors.forename: Cai-gang
authors.initials: CG
authors.lastname: Liu
authors.forename: Ping
authors.initials: P
authors.lastname: Lu
authors.forename: Yang
authors.initials: Y
authors.lastname: Lu
authors.forename: Shu-bao
authors.initials: SB
authors.lastname: Wang
authors.forename: Jun-qing
authors.initials: JQ
authors.lastname: Chen
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008113:Liver Neoplasms / Q000556:secondary / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D009362:Neoplasm Metastasis; D009367:Neoplasm Staging; D011379:Prognosis; D012189:Retrospective Studies; D013274:Stomach Neoplasms / Q000473:pathology* / Q000601:surgery*; D015996:Survival Rate