title: Sporotrichosis in childhood: clinical and therapeutic experience in 25 patients.
abstract: Sporotrichosis in an uncommon mycoses in childhood and is generally associated with injuries received as a consequence of farm work. We undertook a retrospective study of sporotrichosis in children and adolescents seen over a 10-year period, focusing on their clinical, epidemiologic, and mycologic features as well as treatment. We included 25 children with a mean age of 9.3 years. Most of those affected were schoolchildren (84%) from rural areas. The main clinical variety of sporotrichosis seen was the lymphocutaneous form (64%), followed by the fixed cutaneous form (36%), and one instance of the disseminated cutaneous form. Most lesions were located on the upper limbs (40%) and the face (36%). Sporothrix schenckii was isolated in all patients and 24 of 25 had a positive sporotrichin skin test. Nineteen patients were treated and cured clinically and mycologically with potassium iodide, three were cured with itraconazole and one with heat therapy.
authors.affiliation: Mycology Department, Hospital General de Mexico, Mexico City, Mexico. a_bonifaz@yahoo.com.mx
authors.forename: Alexandro
authors.initials: A
authors.lastname: Bonifaz
authors.forename: Amado
authors.initials: A
authors.lastname: Saúl
authors.forename: Vanessa
authors.initials: V
authors.lastname: Paredes-Solis
authors.forename: Leonel
authors.initials: L
authors.lastname: Fierro
authors.forename: Alejandra
authors.initials: A
authors.lastname: Rosales
authors.forename: Carolina
authors.initials: C
authors.lastname: Palacios
authors.forename: Javier
authors.initials: J
authors.lastname: Araiza
mesh_terms: D000293:Adolescent; D000935:Antifungal Agents / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D015331:Cohort Studies; D006801:Humans; D006979:Hyperthermia, Induced; D007223:Infant; D017964:Itraconazole / Q000627:therapeutic use; D011193:Potassium Iodide / Q000627:therapeutic use; D012189:Retrospective Studies; D013175:Sporothrix; D013174:Sporotrichosis / Q000175:diagnosis* / Q000382:microbiology / Q000628:therapy*; D016896:Treatment Outcome
chemical_list: D000935:Antifungal Agents; D011193:Potassium Iodide; D017964:Itraconazole