Giant verrucous porokeratosis of Mibelli mimicking psoriasis in a patient with psoriasis.
Porokeratosis of Mibelli is a disorder of epidermal keratinization characterized by annular plaques with an atrophic center surrounded by a keratotic wall. We report a case of a giant verrucous porokeratosis of Mibelli mimicking psoriasis that developed in a patient with psoriasis and therefore went unrecognized for a long time. Histologically the lesion combined features of porokeratosis at the periphery and of psoriasis at its center, a picture recently described as "psoriasis encircled by porokeratosis." The possible pathogenetic relationship between psoriasis and the development of porokeratosis is also discussed.
De Simone
Clara
C
Department of Dermatology, Università Cattolica del Sacro Cuore, Rome, Italy.
Paradisi
Andrea
A
Massi
Guido
G
Proietti
Ilaria
I
Capponi
Angela
A
Amerio
Pier Luigi
PL
Capizzi
Rodolfo
R
D000368:Aged; D003937:Diagnosis, Differential; D003951:Diagnostic Errors; D005260:Female; D006801:Humans; D017499:Porokeratosis / Q000175:diagnosis* / Q000473:pathology; D011565:Psoriasis / Q000175:diagnosis*