title: [Photoaging of a skin].
abstract: Photoaging is a skin aging caused by long-term exposure to the ultraviolet radiations of the sun. Ultraviolet activates activating protein-1 and generate reactive oxygen species which play a substantial role in collagen degradation. Clinically, photoaged skin appears as a coarse with deep wrinkles. Presently there are available several agents to reverse the photodamage. There is conclusive evidence that synthetic vitamin A derivatives are the most effective in the treatment of photoaging. Erythema and scaling may be experienced initially.
authors.affiliation: Akademia Medyczna w Warszawie, Katedra i Zakład Histologii i Embriologii Centrum Biostruktury. rgalus@ib.amwaw.edu.pl
authors.forename: Ryszard
authors.initials: R
authors.lastname: Galus
authors.forename: Łukasz
authors.initials: Ł
authors.lastname: Zandecki
authors.forename: Marek
authors.initials: M
authors.lastname: Antiszko
authors.forename: Katarzyna
authors.initials: K
authors.lastname: Borowska
authors.forename: Stanisław
authors.initials: S
authors.lastname: Zabielski
mesh_terms: D000818:Animals; D006801:Humans; D012867:Skin / Q000528:radiation effects*; D015595:Skin Aging / Q000187:drug effects; D014466:Ultraviolet Rays / Q000009:adverse effects*; D014801:Vitamin A / Q000494:pharmacology
chemical_list: D014801:Vitamin A