title: Short synthesis of the C16-C28 polyketide fragment of apoptolidin A aglycone.
abstract: Starting from (E,E)-1-[(1R)-(phenylethyl)oxy]-2-methylpenta-1,3-diene and triethylsilyl enol ether of butanone rapid access to Koert's advanced C10-C28 polyketide fragment of apoptolidin A is now possible.
authors.affiliation: Institute of Pharmaceutical Sciences, ETH Zürich, Wolfgang-Pauli-Strasse 10, CH, 8093 Zürich, Switzerland.
authors.forename: Cotinica
authors.initials: C
authors.lastname: Craita
authors.forename: Charles
authors.initials: C
authors.lastname: Didier
authors.forename: Pierre
authors.initials: P
authors.lastname: Vogel
mesh_terms: D018942:Macrolides / Q000138:chemical synthesis*; D011753:Pyrones / Q000138:chemical synthesis*
chemical_list: D018942:Macrolides; D011753:Pyrones; C506738:apoptolidin A