title: Early reintervention of compromised free flaps improves success rate.
abstract: OBJECTIVE
  To develop a protocolized monitor schedule in microvascular free flap reconstruction, we investigated a possible correlation between the outcome and the interval between clamp release and start of revision.
  
  
  METHODS
  All the charts of patients treated between 2000 and 2006 with a free flap were evaluated. The patients who underwent a flap revision were further analyzed.
  
  
  RESULTS
  A total of 608 free flaps were evaluated; 69 of these flaps were revised. Most vascular complications took place within the first 24 h; the latest complication was observed 8 days after surgery. After 6 days post surgery, the number of revisions decreased considerably. With regard to the salvaged flaps the mean time to start the revision was 46.5 h (SD 39). With regard to the failed revisions, the mean time to start the revision was 82.0 h (SD 47). This difference proved significant (P = 0.006).
  
  
  CONCLUSIONS
  Our data shows that the majority of anastomotic failures occur within the first 24 h. Thereafter, the frequency of failures decreases. We also found that the time between initial reconstruction and start of the salvage procedure influences the outcome of the revision negatively.
authors.affiliation: Department of Plastic and Reconstructive Surgery, Uppsala University Hospital, Uppsala, Sweden. jermasmit@gmail.com
authors.forename: Jeroen M
authors.initials: JM
authors.lastname: Smit
authors.forename: Rafael
authors.initials: R
authors.lastname: Acosta
authors.forename: Clark J
authors.initials: CJ
authors.lastname: Zeebregts
authors.forename: Anders G
authors.initials: AG
authors.lastname: Liss
authors.forename: Matti
authors.initials: M
authors.lastname: Anniko
authors.forename: Ed H M
authors.initials: EH
authors.lastname: Hartman
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D002675:Child, Preschool; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D008297:Male; D008866:Microsurgery; D008875:Middle Aged; D011183:Postoperative Complications; D019651:Plastic Surgery Procedures; D012086:Reoperation; D012189:Retrospective Studies; D013524:Surgical Flaps / Q000009:adverse effects* / Q000098:blood supply*; D013997:Time Factors; D016896:Treatment Outcome