title: Selective cord coagulation in acardiac twins.
abstract: The twin reverse arterial perfusion (TRAP) sequence is a serious complication of monochorionic multiple pregnancies in which the affected twin is reversely perfused from the healthy co-twin, resulting in severely abnormal or absent cardiac development, severe malformations, and massive hydrops fetalis. The acardiac twin threatens the survival of the pump twin either by increasing the risk of congestive cardiac failure or by the development of polyhydramnios, preterm premature rupture of membranes, preterm labour and premature delivery. A wide spectrum of surgical interventions has been applied in the management of TRAP; however, because of the rarity of this condition and the heterogeneity of its presentation, no single technique has been shown to be unequivocally optimal. In our experience, fetoscopic laser coagulation of the placental vascular anastomoses or the umbilical cord of the acardiac twin, with the possibility of applying bipolar forceps as an additional minimally invasive surgical technique, offers an effective treatment option in the management of the TRAP sequence; this treatment has a survival rate of 80%, and 67% of pregnancies with surviving pump twins go beyond 36 weeks of gestation without further complications.
authors.affiliation: Department of Obstetrics and Fetal Medicine, University Medical Centre, Hamburg-Eppendorf (UKE), Martinistrasse 52, 20246 Hamburg, Germany. wdiehl@uke.uni-hamburg.de
authors.forename: W
authors.initials: W
authors.lastname: Diehl
authors.forename: K
authors.initials: K
authors.lastname: Hecher
mesh_terms: D005260:Female; D005318:Fetal Heart / Q000002:abnormalities; D005330:Fetofetal Transfusion / Q000601:surgery*; D005332:Fetoscopy / Q000379:methods; D006801:Humans; D017075:Laser Coagulation / Q000379:methods*; D010920:Placenta / Q000098:blood supply; D011247:Pregnancy; D011256:Pregnancy Outcome; D018607:Pregnancy Reduction, Multifetal / Q000379:methods; D016896:Treatment Outcome; D014430:Twins, Monozygotic; D014470:Umbilical Cord / Q000601:surgery*