title: [Diagnostic value of serum amyloid A protein (SAA) determination].
abstract: Although serum amyloid A (SAA) was discovered almost 25 years ago, its biological role is still unknown. Similarly to C-reactive protein, SAA belongs to acute reaction proteins, synthesised in the liver after stimulation by proinflammatory cytokines like: TNFalpha, IL-1beta and IL-6. SAA level in acute inflammatory process of bacterial, mycotical, autoimmunological, oncological or extensive tissue damage is from 100 to 1000 mg/l. Additional SAA examination in patients with oncological disorders is accepted as a valuable survival index.
authors: Zakład Diagnostyki Katedra Biochemii, Klinicznej Collegium Medicum, Uniwersytetu Jagiellońskiego w Krakowie. mbkusnie@cyf-kr.edu.pl
authors: Beata
authors: B
authors: Kuśnierz-Cabala
authors: Danuta
authors: D
authors: Galicka-Latała
authors: Jerzy W
authors: JW
authors: Naskalski
mesh_terms: D015415:Biomarkers / Q000032:analysis; D014408:Biomarkers, Tumor / Q000032:analysis; D002097:C-Reactive Protein / Q000032:analysis / Q000096:biosynthesis; D006801:Humans; D011237:Predictive Value of Tests; D012680:Sensitivity and Specificity; D000685:Serum Amyloid A Protein / Q000032:analysis* / Q000096:biosynthesis*
chemical_list: D015415:Biomarkers; D014408:Biomarkers, Tumor; D000685:Serum Amyloid A Protein; D002097:C-Reactive Protein