Pernicious anemia in a young man with systemic lupus erythematosus.
Association of pernicious anemia and systemic lupus erythematosus is rare, although both diseases are autoimmune origin. We describe the case of a 40-year old man with systemic lupus erythematosus (SLE) who developed pernicious anemia. The cobalamin deficiency was revealed by macrocytic pancytopenia. After 1 month of vitamin B12 treatment, hemoglobin and white blood cell count remain normal but thrombocytopenia persists and was considered as immunologic from SLE origin requiring corticosteroids.
Benjilali
L
L
Department of Internal Medicine, Ibn Sina Hospital, Rabat, Morroco.
Tazi-Mezalek
Z
Z
Harmouche
H
H
Lebbar
K
K
Aouni
M
M
Adnaoui
M
M
Maaouni
A
A
D000305:Adrenal Cortex Hormones / Q000009:adverse effects; D000328:Adult; D000748:Anemia, Macrocytic; D000752:Anemia, Pernicious / Q000209:etiology*; D006454:Hemoglobins / Q000032:analysis; D006801:Humans; D007958:Leukocyte Count; D008180:Lupus Erythematosus, Systemic / Q000150:complications* / Q000188:drug therapy; D008297:Male; D013921:Thrombocytopenia / Q000209:etiology / Q000276:immunology
D000305:Adrenal Cortex Hormones; D006454:Hemoglobins