Herpes zoster ophthalmicus complicated by complete ophthalmoplegia and signs of pilocarpine hypersensitivity. A case report and literature review.
We report a case of zona ophthalmica complicated with a complete ophthalmoplegia. In the literature only 19 cases have been reported the last 30 years, with a variety of possible pathophysiological mechanisms. Our patient's mydriasis reacted to diluted pilocarpine 0.125% which is a sign of Adie's pupil and is not supposed to occur in mydriasis caused by a third nerve palsy. We review the literature on the possible pathogenesis of this hypersensitivity.
Pion
B
B
Dept. of Ophthalmology, Academic Hospital of the Free University of Brussels, Laarbeeklaan 101, B-1090 Jette. bartpion@hotmail.com
Salu
P
P
D000212:Acyclovir / Q000008:administration & dosage; D000368:Aged; D000544:Alzheimer Disease / Q000150:complications; D001562:Benzimidazoles / Q000627:therapeutic use; D004342:Drug Hypersensitivity / Q000209:etiology*; D004359:Drug Therapy, Combination; D005260:Female; D006563:Herpes Zoster Ophthalmicus / Q000150:complications* / Q000188:drug therapy; D006801:Humans; D006980:Hyperthyroidism / Q000150:complications; D007275:Injections, Intravenous; D009886:Ophthalmoplegia / Q000209:etiology*; D010051:Ovarian Neoplasms / Q000150:complications; D010862:Pilocarpine / Q000627:therapeutic use*
D001562:Benzimidazoles; C483319:methylproamine; D010862:Pilocarpine; D000212:Acyclovir