Multivessel coronary artery spasm refractory to intensive medical treatment.
This case report describes multivessel coronary artery spasm refractory to oral nifedipine, intravenous isosorbide dinitrate, diltiazem and nicorandil, and intracoronary nitroglycerin. Intracoronary administration of nicorandil only transiently relieved coronary artery spasm. Prednisolone was effective in preventing coronary artery spasm.
Asano
Tatsuhiko
T
Department of Cardiovascular Science and Medicine, Chiba University Graduate School of Medicine, Chiba, Japan.
Kobayashi
Yoshio
Y
Ohno
Masaki
M
Nakayama
Takashi
T
Kuroda
Nakabumi
N
Komuro
Issei
I
D000284:Administration, Oral; D000328:Adult; D000787:Angina Pectoris / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology; D017023:Coronary Angiography; D023921:Coronary Stenosis / Q000150:complications / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology; D003329:Coronary Vasospasm / Q000150:complications / Q000188:drug therapy* / Q000473:pathology; D004110:Diltiazem / Q000627:therapeutic use; D004562:Electrocardiography; D005260:Female; D005938:Glucocorticoids / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D007262:Infusions, Intravenous; D007548:Isosorbide Dinitrate / Q000627:therapeutic use; D020108:Nicorandil / Q000627:therapeutic use; D009543:Nifedipine / Q000627:therapeutic use; D005996:Nitroglycerin / Q000627:therapeutic use; D011239:Prednisolone / Q000008:administration & dosage / Q000627:therapeutic use*; D017211:Treatment Failure; D014665:Vasodilator Agents / Q000008:administration & dosage / Q000627:therapeutic use*
D005938:Glucocorticoids; D014665:Vasodilator Agents; D020108:Nicorandil; D011239:Prednisolone; D004110:Diltiazem; D005996:Nitroglycerin; D009543:Nifedipine; D007548:Isosorbide Dinitrate