Screening and diagnosis of prediabetes: where are we headed?
It is currently estimated that more than 300 million people have impaired glucose tolerance (IGT), putting them at increased risk for type 2 diabetes mellitus (T2DM) and its adverse consequences. In addition, many others are at risk on the basis of a family history of T2DM, obesity, dyslipidaemia and hypertension. Screening for risk should include both blood glucose testing in high-risk populations and prescreening (e.g. by questionnaire, waist circumference measurement) to identify high-risk individuals in overall low-risk populations; these individuals should then undergo glucose testing. Fasting plasma glucose measurement cannot diagnose IGT; the preferred definite test for diagnosis is oral glucose tolerance testing.
Alberti
K G M M
KG
Department of Endocrinology and Metabolic Medicine, Imperial College, St Mary's Hospital, London, UK. george.alberti@ncl.ac.uk
D001786:Blood Glucose / Q000032:analysis*; D003924:Diabetes Mellitus, Type 2 / Q000097:blood; D018149:Glucose Intolerance / Q000097:blood / Q000175:diagnosis*; D006801:Humans; D050177:Overweight; D011236:Prediabetic State / Q000097:blood / Q000175:diagnosis*; D012307:Risk Factors
D001786:Blood Glucose