title: Common variable immunodeficiency syndrome associated with epidermodysplasia verruciformis.
abstract: We report the association of common variable immunodeficiency syndrome with epidermodysplasia verruciformis (EV) manifesting as flat warts and squamous cell carcinomas in a 21-year-old Hispanic woman. Human papillomavirus (HPV) typing by polymerase chain reaction using an EV-HPV primer system, cloning, and sequencing detected HPV-8 and HPV-23 DNAs in the biopsy sample. Our case is the second reported case of common variable immunodeficiency syndrome associated with EV.
authors: Department of Dermatology, University of Texas MD Anderson Cancer Center and Medical School, Houston, Texas 77030-4009, USA. jvu@mdanderson.org
authors: Jenny
authors: J
authors: Vu
authors: Genevieve R
authors: GR
authors: Wallace
authors: Rajendra
authors: R
authors: Singh
authors: Hafeez
authors: H
authors: Diwan
authors: Victor
authors: V
authors: Prieto
authors: Peter
authors: P
authors: Rady
authors: Stephen
authors: S
authors: Tyring
authors: Madeleine
authors: M
authors: Duvic
mesh_terms: D000328:Adult; D052686:Betapapillomavirus / Q000235:genetics / Q000302:isolation & purification*; D017074:Common Variable Immunodeficiency / Q000150:complications* / Q000473:pathology / Q000821:virology; D004279:DNA, Viral / Q000032:analysis; D004819:Epidermodysplasia Verruciformis / Q000150:complications* / Q000473:pathology / Q000821:virology; D005260:Female; D006801:Humans; D009061:Mouth Mucosa / Q000473:pathology; D016133:Polymerase Chain Reaction; D012867:Skin / Q000473:pathology
chemical_list: D004279:DNA, Viral