Cytogenetic mapping of eight genes encoding fatty acid binding proteins (FABPs) in the pig genome.
In the present study cytogenetic localization of eight fatty acid binding protein genes in the pig genome was shown. BAC clones, containing sequences of selected genes (FABP1, FABP2, FABP3, FABP4, FABP5, FABP6, FABP7 and FABP8) were derived from porcine BAC libraries and mapped by FISH to porcine chromosomes (SSC) 3q12, 8q25, 6q26, 4q12, 4q12, 16q22, 1p22 and 4q12, respectively. Detailed analyses of regions containing gene clusters (FABP4, FABP5, FABP8) in chromosome 4 were performed and their order was established. It was shown that these three genes are located beyond the FAT1 region. Assignment of the FABP genes to chromosome regions harboring quantitative trait loci (QTL) for fat deposition is discussed.
Szczerbal
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I
Department of Genetics and Animal Breeding, August Cieszkowski Agricultural University of Poznan, Poznan, Poland. izabel@jay.au.poznan.pl
Chmurzynska
A
A
Switonski
M
M
D000818:Animals; D001483:Base Sequence; D002874:Chromosome Mapping; D022202:Chromosomes, Artificial, Bacterial; D017931:DNA Primers; D050556:Fatty Acid-Binding Proteins / Q000235:genetics*; D016678:Genome; D017404:In Situ Hybridization, Fluorescence; D008297:Male; D013552:Swine
D017931:DNA Primers; D050556:Fatty Acid-Binding Proteins