title: Synthesis and biological evaluation of some novel Schiff's bases from 1,2,4-triazole.
abstract: We have synthesized a number of novel Schiff's bases from 4-amino-3-(D-glucoheptonic-hexitol-1-yl)-1H-1,2,4-triazole-5-thione. By attaching D-glucoheptonic-hexitol-1-yl residues to 1,2,4-triazole at the 3-position, the solubility of the title compounds has been improved greatly. All the products have been characterized by elemental analysis, IR, 1H-NMR, 13C-NMR and MS. The plant-growth regulating effects of the title compounds were examined. From the biological activity results, we found that most compounds showed weak to moderate activities.
authors: College of Chemistry and Materials Engineering, Wenzhou University, Wenzhou 325027, PR China.
authors: Xiao-Xia
authors: XX
authors: Ye
authors: Zhen-Fei
authors: ZF
authors: Chen
authors: An-Jiang
authors: AJ
authors: Zhang
authors: Li-Xue
authors: LX
authors: Zhang
mesh_terms: D063245:Plant Development; D010944:Plants / Q000187:drug effects; D012545:Schiff Bases / Q000138:chemical synthesis* / Q000494:pharmacology; D012995:Solubility; D013057:Spectrum Analysis; D014230:Triazoles / Q000737:chemistry*
chemical_list: D012545:Schiff Bases; D014230:Triazoles