Inherited platelet disorders.
Inherited platelet disorders are a rare, but probably underdiagnosed, cause of symptomatic bleeding. They are characterized by abnormalities of platelet number (inherited thrombocytopenias), function (inherited disorders of platelet function) or both. This review briefly discusses the inherited platelet disorders with respect to molecular defects, diagnostic evaluation and treatment strategies.
Franchini
Massimo
M
Servizio di Immunoematologia e Trasfusione-Centro Emofilia, Azienda Ospedaliera di Verona, Italy. mfranchini@univr.it
Lippi
Giuseppe
G
Veneri
Dino
D
Targher
Giovanni
G
Zaffanello
Marco
M
Guidi
Gian Cesare
GC
D001792:Blood Platelets / Q000166:cytology / Q000502:physiology*; D006402:Hematologic Diseases / Q000097:blood / Q000145:classification / Q000235:genetics*; D006801:Humans