title: Resolution of an oral ulcer secondary to acetaminophen/hydrocodone withdrawal.
abstract: Acetaminophen/hydrocodone is a common non-opioid/opioid analgesic indicated for the treatment of moderate to severe pain. The following report depicts a unique case involving a 57-year-old woman with a persistent, painful oral ulcer that was unresponsive to standard treatments. The ulcer was resolved when the patient discontinued acetaminophen/hydrocodone use. The cause of the ulcer is unclear but it was speculated to result from a systemic hypersensitivity reaction to acetaminophen/hydrocodone.
authors: Orofacial Pain Center, College of Dentistry and Medicine, University of Kentucky, Lexington, USA.
authors: Ramesh
authors: R
authors: Balasubramaniam
authors: Po-Ching
authors: PC
authors: Lin
authors: Dean K
authors: DK
authors: White
authors: Juan F
authors: JF
authors: Yepes
mesh_terms: D000082:Acetaminophen / Q000009:adverse effects*; D000701:Analgesics, Opioid / Q000009:adverse effects*; D004338:Drug Combinations; D004342:Drug Hypersensitivity / Q000209:etiology*; D005260:Female; D006801:Humans; D006853:Hydrocodone / Q000009:adverse effects*; D017116:Low Back Pain / Q000188:drug therapy; D008875:Middle Aged; D019226:Oral Ulcer / Q000139:chemically induced*
chemical_list: D000701:Analgesics, Opioid; D004338:Drug Combinations; C083640:acetaminophen, hydrocodone drug combination; D000082:Acetaminophen; D006853:Hydrocodone