[Exploration on the relationship between diabetic peripheral neuropathy and oxidative stress QU ling and].
The pathogenesis of diabetic peripheral neuropathy (DPN) is not illustrated clearly nowadays, and there are several hypotheses. Oxidative stress response is penetrated in several different hypotheses as the formation of advanced glycosylation end products, polyhydric alcohol metabolic pathway, protein kinase C activation and microvascular lesion, etc. The influence of oxidative stress on DPN and the current status of anti-oxidation therapy by using integrative traditional and Western medicine were reviewed in this paper.
Qu
Ling
L
Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing.
Liang
Xiao-chun
XC
D000975:Antioxidants / Q000627:therapeutic use*; D003929:Diabetic Neuropathies / Q000188:drug therapy* / Q000503:physiopathology; D004359:Drug Therapy, Combination; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D006801:Humans; D018384:Oxidative Stress / Q000187:drug effects* / Q000502:physiology; D010525:Peripheral Nerves / Q000187:drug effects / Q000473:pathology / Q000503:physiopathology; D008517:Phytotherapy
D000975:Antioxidants; D004365:Drugs, Chinese Herbal