title: Pregnane glycosides from Solanum nigrum.
abstract: Two new pregnane saponins, solanigroside A (1) and solanigroside B (2), along with two known compounds (3 and 4), were isolated from 60% ethanolic extract of the dried herb of Solanum nigrum L. The structures of 1 and 2 were elucidated as 5alpha-pregn-16-en-3beta-ol-20-one 3-O-beta-D-xylopyranosyl-(1 --> 3)-O-[alpha-L-arabinopyranosyl-(1 --> 2)]-O-beta-D-glucopyranosyl-(1 --> 4)-O-[alpha-L-rhamnopyranosyl-(1 --> 2)]-O-beta-D-galactopyranoside (1) and 5alpha-pregn-16-en-3beta-ol-20-one 3-O-beta-D-glucopyranosyl-(1 --> 2)-O-[beta-D-glucopyranosyl-(1 --> 3)]-O-beta-D-glucopyranosyl-(1 --> 4)-O-beta-D-galactopyranoside (2), respectively, on the basis of extensive spectroscopic analysis as well as comparison with reported spectroscopic data of related compounds. This paper deals with the isolation and structural characterisation of pregnane glycosides from S. nigrum L.
authors: Department of Natural Products Chemistry, Shenyang Pharmaceutical University, Shenyang, China.
authors: Xin-Lan
authors: XL
authors: Zhou
authors: Xiang-Jing
authors: XJ
authors: He
authors: Guang-Xiong
authors: GX
authors: Zhou
authors: Wen-Cai
authors: WC
authors: Ye
authors: Xin-Sheng
authors: XS
authors: Yao
mesh_terms: D002236:Carbohydrate Conformation; D002240:Carbohydrate Sequence; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification*; D009682:Magnetic Resonance Spectroscopy; D008969:Molecular Sequence Data; D011278:Pregnanes / Q000737:chemistry / Q000302:isolation & purification*; D032322:Solanum / Q000737:chemistry*; D021241:Spectrometry, Mass, Electrospray Ionization
chemical_list: D006027:Glycosides; D011278:Pregnanes