Pancreatic ductal adenocarcinoma associated with pancreatic ductal intraepithelial neoplasia: report of a case.
BACKGROUND
The presence of pancreatic ductal intraepithelial neoplasia in patients with chronic pancreatitis is a risk factor for development of pancreatic adenocarcinoma.


METHODS
A case of pancreatic ductal adenocarcinoma associated with pancreatic ductal intraepithelial neoplasia was diagnosed in the setting of chronic pancreatitis.


RESULTS
Distal pancreatectomy combined with splenectomy was performed with a diagnosis of pancreatic body carcinoma. Histopathological examination suggested adenocarcinoma associated with pancreatic ductal intraepithelial neoplasia. The tumor was detected in the remaining head of the pancreas, for which a total pancreatectomy was done.


CONCLUSIONS
When a patient with pancreatic ductal intraepithelial neoplasia associated with adenocarcinoma of the pancreas in the setting of chronic pancreatitis is at an increased risk of recurrence in the remaining pancreatic parenchyma, total pancreatectomy may be feasible.
Krishnasamy
Rajkumar
R
Department of Gastrointestinal Surgery, Govind Ballabh Pant Hospital and Maulana Azad Medical College (Delhi University), New Delhi 110002, India.
Agarwal
Shaleen
S
Singh
Shivendra
S
Puri
Sunil
S
Sakhuja
Puja
P
Agarwal
Anil K
AK
D002278:Carcinoma in Situ / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D021441:Carcinoma, Pancreatic Ductal / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D003937:Diagnosis, Differential; D005500:Follow-Up Studies; D006801:Humans; D010535:Laparoscopy; D007813:Laparotomy / Q000379:methods; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary; D010180:Pancreatectomy / Q000379:methods; D010190:Pancreatic Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D013156:Splenectomy / Q000379:methods; D014057:Tomography, X-Ray Computed