Keratinocyte cytokine and chemokine receptors.
Chemokines are a superfamily of small, secreted proteins that regulate cell traffic in homeostatic and inflammatory conditions. Keratinocytes synthesize many chemokines, including members of the CC and CXC subfamilies, such as regulated on activation of normal T-cell expressed and secreted, gamma-interferon inducible protein-10, monokine induced by gamma-interferon, and thymus- and activation-regulated chemokine. They also express some chemokine receptors that mediate the inflammatory or immune response by attracting various kinds of leukocytes.
Tüzün
Yalçin
Y
Department of Dermatology, Cerrahpasa Medical Faculty, Istanbul University, 34098 Istanbul, Turkey. yalcintuzun@yahoo.com
Antonov
Meltem
M
Dolar
Neslihan
N
Wolf
Ronni
R
D016207:Cytokines / Q000235:genetics / Q000502:physiology*; D006801:Humans; D015603:Keratinocytes / Q000502:physiology* / Q000528:radiation effects; D019707:Receptors, Chemokine / Q000502:physiology*; D012871:Skin Diseases / Q000503:physiopathology*; D014466:Ultraviolet Rays
D016207:Cytokines; D019707:Receptors, Chemokine