title: Residual water suppression by indirect covariance NMR.
abstract: Residual water solvent signals in 2D NMR experiments adversely affect appearance and subsequent analysis of spectra. A method for water suppression that is based on indirect covariance processing is described. It produces a symmetric spectrum with a water signal that is substantially decreased or completely absent. The method, which can be combined with other water suppression schemes, is demonstrated for 2D TOCSY, NOESY, and ROESY spectra of the protein, ubiquitin in aqueous solution.
authors: Department of Chemistry and Biochemistry, Florida State University, Tallahassee, FL 32306, USA.
authors: Yanbin
authors: Y
authors: Chen
authors: Fengli
authors: F
authors: Zhang
authors: Rafael
authors: R
authors: Brüschweiler
mesh_terms: D005583:Fourier Analysis; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D019906:Nuclear Magnetic Resonance, Biomolecular / Q000379:methods; D025801:Ubiquitin / Q000032:analysis / Q000737:chemistry; D014867:Water / Q000737:chemistry*
chemical_list: D025801:Ubiquitin; D014867:Water