IA, database of known ligands of aminoacyl-tRNA synthetases.
The IA database contains 240 structures of known inhibitors of aminoacyl-tRNA synthetases. Structures can be downloaded in different file formats (mol, sdf, smile, png). The search engine offers possibility of searching for the ligands with a given functional group. Additionally, one can search for ligands that act on selected synthetases and from particular references. The data include information which synthetase a given ligand inhibits together with the inhibition constant (IC50) if known.
Torchala
Mieczyslaw
M
BioInfoBank Institute, ul. Limanowskiego 24A, Poznan, 60-744, Poland.
Hoffmann
Marcin
M
D000604:Amino Acyl-tRNA Synthetases / Q000737:chemistry* / Q000235:genetics / Q000378:metabolism; D001665:Binding Sites; D016208:Databases, Factual; D007700:Kinetics; D012343:RNA, Transfer; D013329:Structure-Activity Relationship
D012343:RNA, Transfer; D000604:Amino Acyl-tRNA Synthetases