Antibiotic sensitivity pattern of Citrobacter isolated from various clinical specimens in a tertiary care hospital.
A total of 709 isolates of Citrobacter species were recovered from different clinical specimens at Kasturba Medical College, Mangalore. The antimicrobial susceptibility testing of the isolates was performed using Kirby-Bauer's method of disk diffusion. All the isolates were susceptible to Imipenem (100%) and 100% resistance to Ampicillin was recorded. Susceptibility to third generation cephalosporins varied between 29 - 43%. The beta-lactamase inhibitor combination used along with beta-lactam antibiotics increased their sensitivity. The minimum inhibitory concentration (MIC) of cephotaxime to Citrobacter species was determined by agar dilution method (MIC value = or < 8 microg/ml are considered susceptible). Two hundred and fifty three strains were found to be completely susceptible, 71 strains showed intermediate susceptibility and 385 strains were completely resistant to Cephotaxime.
Shetty
Jeevan
J
Department of Microbiology, SDM College of Medical Sciences and Hospital, Dharwad, Karnataka. drjeesh@yahoo.co.in
Kotigadde
Subbannayya
S
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D002954:Citrobacter / Q000187:drug effects* / Q000302:isolation & purification; D003428:Cross Infection / Q000453:epidemiology / Q000382:microbiology*; D024881:Drug Resistance, Bacterial; D004756:Enterobacteriaceae Infections / Q000453:epidemiology / Q000382:microbiology*; D006761:Hospitals; D006801:Humans; D007194:India / Q000453:epidemiology; D008826:Microbial Sensitivity Tests
D000900:Anti-Bacterial Agents