A new approach to enantiopure inherently chiral calix[4]arenes: determination of their absolute configurations.
A new approach to the synthesis of meta-substituted enantiopure inherently chiral calix[4]arenes by introducing L-Boc-proline as dual functions of the chiral auxiliary has been described. Moreover, the absolute configurations of the enantiomers were determined by CD spectra, X-ray crystallographic analysis, and the chemical derivative method.
Xu
Zhen-Xiang
ZX
Beijing National Laboratory for Molecular Sciences, Center for Chemical Biology, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100080, China, and Graduate School, Chinese Academy of Sciences, Beijing 100049, China.
Zhang
Chun
C
Zheng
Qi-Yu
QY
Chen
Chuan-Feng
CF
Huang
Zhi-Tang
ZT