title: Nephrotic syndrome resulting from focal segmental glomerulosclerosis in a peripheral blood stem cell transplant patient.
abstract: We describe the case of a male patient who was diagnosed with acute monoblastic leukemia and received a peripheral stem cell transplantation (PSCT) with peripheral blood hematopoietic progenitors. Because he was in clinical remission with no evidence of chronic graft-versus-host disease (GVHD), immunosuppression was withdrawn, and he developed nephrotic syndrome (NS) months later. A kidney biopsy showed focal segmental glomerulosclerosis (FSGS) as part of the GVHD. Soon after the reintroduction of previous immunosuppressive therapy, we observed a complete remission of the NS.
authors: Department of Nephrology, Segovia General Hospital, Segovia, Spain.
authors: Manuel
authors: M
authors: Heras
authors: Ana
authors: A
authors: Saiz
authors: Rosa
authors: R
authors: Sánchez
authors: Maria José
authors: MJ
authors: Fernandez-Reyes
authors: Francisco
authors: F
authors: Mampaso
authors: José  Antonio
authors: J
authors: Queizán
authors: Alvaro
authors: A
authors: Molina
authors: Lourdes
authors: L
authors: Vázquez
authors: Fernando
authors: F
authors: Alvarez-Ude
mesh_terms: D000328:Adult; D005923:Glomerulosclerosis, Focal Segmental / Q000150:complications* / Q000276:immunology / Q000473:pathology; D006086:Graft vs Host Disease / Q000150:complications* / Q000276:immunology / Q000473:pathology; D018380:Hematopoietic Stem Cell Transplantation; D006801:Humans; D007165:Immunosuppression Therapy; D007948:Leukemia, Monocytic, Acute / Q000628:therapy; D008297:Male; D009404:Nephrotic Syndrome / Q000175:diagnosis* / Q000209:etiology / Q000628:therapy