Fanconi anemia presenting as acute myeloid leukemia: a case report.
Fanconi anemia is an autosomal recessive disorder characterized by phenotypic abnormalities, increased chromosomal breaks and predisposition to various hematological and non-hematological malignancies. We present case report of a paediatric patient with Fanconi anemia presenting as acute myeloid leukemia. The presence of dysplastic features in this marrow suggests the possibility of a prior stage of myelodysplasia progressing to leukemia.
Bhatia
Alka
A
Department of Haematology, Postgraduate Institute of Medical Education and Research, Chandigarh.
Dash
Sumitra
S
Varma
Neelam
N
Marwaha
R K
RK
D001853:Bone Marrow / Q000473:pathology; D002648:Child; D019457:Chromosome Breakage; D003937:Diagnosis, Differential; D005199:Fanconi Anemia / Q000175:diagnosis* / Q000235:genetics / Q000473:pathology; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000175:diagnosis* / Q000473:pathology; D008297:Male; D009436:Neural Tube Defects / Q000175:diagnosis / Q000473:pathology