[A study in extraction method of buprenorphine in urine].
OBJECTIVE
The extraction method for separating buprenorphine from urine was described.


METHODS
Buprenorphine was extracted with chloroform at pH7 or with SPE (extracted by organic support 401 at pH10.8, then eluted with chloroform), finally determined by GC-NPD.


RESULTS
The extracted yields of the analyte in specimens were 86.6% by solution-phase extraction and 83.0% by solid-phase extraction (SPE) respectively.


CONCLUSIONS
These two methods are simple and accurate for separating buprenorphine from urine.
Liu
Dong-xian
DX
Department of Criminal technology, Hunan Public Security College, Changsha 410138, China. liudongxian@yahoo.com.cn
He
Jiang-nan
JN
D002047:Buprenorphine / Q000737:chemistry / Q000302:isolation & purification / Q000652:urine*; D002748:Chlorpropham / Q000737:chemistry; D002849:Chromatography, Gas / Q000379:methods*; D002853:Chromatography, Liquid / Q000379:methods; D006801:Humans; D006863:Hydrogen-Ion Concentration; D015203:Reproducibility of Results; D052616:Solid Phase Extraction / Q000379:methods*; D012997:Solvents / Q000737:chemistry
D012997:Solvents; D002748:Chlorpropham; D002047:Buprenorphine