Status epilepticus secondary to hypertensive encephalopathy as the presenting manifestation of Guillain-Barré syndrome.
Malignant hypertension due to autonomic dysfunction is a known complication of Guillain-Barré syndrome. We describe a child who presented with status epilepticus secondary to hypertensive encephalopathy who, in recovery, was found to be areflexic. Nerve conduction studies confirmed the clinical diagnosis of Guillain-Barré syndrome. She was treated with antihypertensive and antiseizure medications and intravenous immune globulin with complete resolution of her autonomic symptoms and improvement in her weakness. Guillain-Barré syndrome may result in hypertensive encephalopathy that can manifest as status epilepticus before the onset of motor symptoms.
Abend
Nicholas S
NS
Division of Neurology, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA. abend@email.chop.edu
Bonnemann
Carsten G
CG
Licht
Daniel J
DJ
D000293:Adolescent; D000588:Amines / Q000627:therapeutic use; D000927:Anticonvulsants / Q000627:therapeutic use; D000959:Antihypertensive Agents / Q000627:therapeutic use; D003509:Cyclohexanecarboxylic Acids / Q000627:therapeutic use; D003937:Diagnosis, Differential; D004569:Electroencephalography; D005260:Female; D000077206:Gabapentin; D020275:Guillain-Barre Syndrome / Q000175:diagnosis*; D006801:Humans; D020343:Hypertensive Encephalopathy / Q000175:diagnosis* / Q000188:drug therapy; D007136:Immunoglobulins / Q000627:therapeutic use; D007741:Labetalol / Q000627:therapeutic use; D010672:Phenytoin / Q000627:therapeutic use; D013129:Spinal Puncture; D013226:Status Epilepticus / Q000175:diagnosis* / Q000188:drug therapy; D014057:Tomography, X-Ray Computed; D005680:gamma-Aminobutyric Acid / Q000627:therapeutic use
D000588:Amines; D000927:Anticonvulsants; D000959:Antihypertensive Agents; D003509:Cyclohexanecarboxylic Acids; D007136:Immunoglobulins; D005680:gamma-Aminobutyric Acid; D010672:Phenytoin; D000077206:Gabapentin; D007741:Labetalol