title: Fatty liver due to high levels of serum tacrolimus after liver transplantation.
abstract: Tacrolimus has been used extensively for immunosuppressive therapy in pediatric liver transplant recipients. However, patients who are exposed to high levels of serum tacrolimus tend to be associated with a higher incidence of significant nephrotoxicity, neurotoxicity, pruritus, alopecia, diabetes and infection. We herein report a child who developed increased serum transaminase levels and liver steatosis as a result of raised trough blood level of tacrolimus (30 ng/ml for 3 days) in association with rotavirus gastroenteritis.
authors: Department of Pediatric Gastroenterology, Hepatology and Nutrition, Ege University, Faculty of Medicine, Izmir, Turkey.
authors: Gökhan
authors: G
authors: Tümgör
authors: Ciğdem
authors: C
authors: Ankan
authors: Deniz
authors: D
authors: Nart
authors: Murat
authors: M
authors: Kihiç
authors: Sema
authors: S
authors: Aydoğdu
mesh_terms: D001706:Biopsy; D002675:Child, Preschool; D005234:Fatty Liver / Q000139:chemically induced*; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects* / Q000097:blood; D016031:Liver Transplantation; D016559:Tacrolimus / Q000009:adverse effects* / Q000097:blood
chemical_list: D007166:Immunosuppressive Agents; D016559:Tacrolimus