Highly diastereoselective nucleophilic addition to myrtenal. Straightforward synthesis of an enantiopure scorpionate ligand.
The work described here represents the first example in which an efficient and highly diastereoselective nucleophilic 1,2-addition of an organolithium reagent has been performed on a carbonylic prostereogenic center to give an enantiopure scorpionate ligand in only one step.
Otero
Antonio
A
Departamento de Química Inorgánica, Orgánica y Bioquímica, Universidad de Castilla-La Mancha, Campus Universitario, 13071 Ciudad Real, Spain. antonio.otero@uclm.es
Fernandez-Baeza
Juan
J
Antiñolo
Antonio
A
Tejeda
Juan
J
Lara-Sanchez
Agustín
A
Sanchez-Barba
Luis F
LF
Sanchez-Molina
Margarita
M
Franco
Sonia
S
López-Solera
Maria I
MI
Rodríguez
Ana M
AM