title: Red light phototherapy alone is effective for acne vulgaris: randomized, single-blinded clinical trial.
abstract: BACKGROUND
  Recently, a demand for safe and effective treatment of acne has been increasing. Although visible light has attracted attention as a new option, the effect of red light alone has not yet been evaluated.
  
  
  OBJECTIVE
  The objective was to assess the efficacy of red light phototherapy with a portable device in acne vulgaris.
  
  
  METHODS
  Twenty-eight volunteers with mild to moderate acne were treated with portable red light-emitting devices in this split-face randomized trial. The right or left side of the face was randomized to treatment side and phototherapy was performed for 15 minutes twice a day for 8 weeks. Clinical photographs, lesion counts, and a visual analog scale (VAS) were used to assess each side of the face at baseline and Weeks 1, 2, 4, and 8, and a split-face comparison was performed.
  
  
  RESULTS
  The percent improvement in noninflammatory and inflammatory lesion counts of the treated side was significant compared to the control side (p<.005). VAS decreased from 3.9 to 1.9 on the treatment side and the difference between the treatment and control sides was significant at Week 8 (p<.005).
  
  
  CONCLUSIONS
  This study shows that red light phototherapy alone can be a new therapeutic option for acne vulgaris.
authors: Department of Dermatology, Seoul National University College of Medicine, Seoul, Korea.
authors: Jung Im
authors: JI
authors: Na
authors: Dae Hun
authors: DH
authors: Suh
mesh_terms: D000152:Acne Vulgaris / Q000473:pathology / Q000628:therapy*; D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D010789:Phototherapy / Q000379:methods; D012720:Severity of Illness Index; D016037:Single-Blind Method; D016896:Treatment Outcome