Degradation of the neolignan, burchellin in the hemolymph of the bloodsucking insect Rhodnius prolixus.
The neolignan, burchellin, a natural compound that reduces urine excretion in larvae of the bloodsucking bug, Rhodnius prolixus, a vector of Chagas' disease, is rapidly degraded in the hemolymph of the insect. The main product that accumulates in this tissue has been shown to be piperonyl alcohol. Other catabolites have been identified by GC-MS analysis.
Cabral
Marise M O
MM
Department of Biology, Universidade Severino Sombra, RJ, Brazil. mmaleck@ioc.fiocruz.br
Garcia
Eloi S
ES
Gottlieb
Otto R
OR
Kelecom
Alphonse
A
D000818:Animals; D001572:Benzofurans / Q000097:blood* / Q000378:metabolism; D001592:Benzyl Alcohols / Q000378:metabolism; D014355:Chagas Disease / Q000517:prevention & control; D006458:Hemolymph / Q000378:metabolism*; D019770:Lauraceae; D010575:Pesticides / Q000494:pharmacology*; D010936:Plant Extracts / Q000378:metabolism*; D012239:Rhodnius / Q000378:metabolism*; D013329:Structure-Activity Relationship
D001572:Benzofurans; D001592:Benzyl Alcohols; D010575:Pesticides; D010936:Plant Extracts; C053585:burchellin; C041611:piperonyl alcohol