title: Superoxide dismutase activity in synovial fluids in patients with temporomandibular joint internal derangement.
abstract: OBJECTIVE
  To measure the activity of superoxide dismutase (SOD) in the synovial fluid of patients with temporomandibular joint internal derangement and to show the relationship between the activity of SOD and the severity of the disease.
  
  
  METHODS
  Twenty patients with internal derangement were classified according to Wilkes by clinical radiological examinations. SOD activity was measured by the method based on nitrobluetetrazolium reduction rate.
  
  
  RESULTS
  The activity of SOD seemed to be progressively decreased as the stage of the disease increased.
  
  
  CONCLUSIONS
  The reduction of SOD activity observed may result from insufficient scavenging capacity of free radicals. Further investigation and longitudinal studies are required to determine the role of antioxidants that scavenge the free radicals in temporomandibular joint disorders.
authors: Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, University of Ankara, Ankara, Turkey. oguven@dentistry.ankara.edu.tr
authors: Orhan
authors: O
authors: Güven
authors: Umut Saracoglu
authors: US
authors: Tekin
authors: Ilker
authors: I
authors: Durak
authors: Eugene E
authors: EE
authors: Keller
authors: Murat
authors: M
authors: Hatipoglu
mesh_terms: D000293:Adolescent; D000328:Adult; D005260:Female; D006801:Humans; D004204:Joint Dislocations / Q000201:enzymology*; D008297:Male; D008875:Middle Aged; D012720:Severity of Illness Index; D018709:Statistics, Nonparametric; D013482:Superoxide Dismutase / Q000378:metabolism*; D013582:Synovial Fluid / Q000201:enzymology*; D013704:Temporomandibular Joint / Q000201:enzymology* / Q000473:pathology; D013705:Temporomandibular Joint Disorders / Q000201:enzymology*
chemical_list: D013482:Superoxide Dismutase