title: The effects of laser irradiation on Trichophyton rubrum growth.
abstract: The effects of various laser wavelengths and fluences on the fungal isolate, Trichophyton rubrum, were examined in vitro. Standard-size isolates of T. rubrum were irradiated by using various laser systems. Colony areas were compared for growth inhibition on days 1, 3, and 6 after laser irradiation. Statistically significant growth inhibition of T. rubrum was detected in colonies treated with the 1,064-nm Q-switched Nd:YAG laser at 4 and 8 J/cm(2) and 532-nm Q-switched Nd:YAG laser at 8 J/cm(2). Q-switched Nd:YAG laser at 532- and 1,064-nm wavelengths produced significant inhibitory effect upon the fungal isolate T. rubrum in this in vitro study. However, more in vitro and in vivo studies are necessary to investigate if lasers would have a potential use in the treatment of fungal infections of skin and its adnexa.
authors: Department of Otolaryngology-Head and Neck Surgery, University of Arkansas for Medical Sciences, 4301 West Markham, Slot 543, Little Rock, AR 72205, USA. vuralemrea@uams.edu
authors: Emre
authors: E
authors: Vural
authors: Harry L
authors: HL
authors: Winfield
authors: Alexander W
authors: AW
authors: Shingleton
authors: Thomas D
authors: TD
authors: Horn
authors: Gal
authors: G
authors: Shafirstein
mesh_terms: D003883:Arthrodermataceae / Q000528:radiation effects*; D015169:Colony Count, Microbial; D066298:In Vitro Techniques; D053685:Laser Therapy; D007834:Lasers; D053844:Lasers, Solid-State; D011809:Quinones; D012717:Sesquiterpenes; D014005:Tinea / Q000628:therapy*; D014249:Trichophyton / Q000528:radiation effects*
chemical_list: D011809:Quinones; D012717:Sesquiterpenes; C474262:neodactyloquinone