Infections with atypical mycobacteria in renal transplant recipients.
Infections due to atypical mycobacteria are infrequent in renal transplant recipients but they cause serious morbidity. These pathogens are common in patients with acquired immune deficiency syndrome (AIDS). We report four proven cases of infections caused with atypical mycobacteriae from 1997 to 2003, by different organisms namely, M. chelonei, M.fortuitum, M. abcessus and M. terrae in renal transplant recipients. Infection with M. terrae documented here is the first occurrence in a renal transplant patient. Histopathological examination of aspirates or biopsy specimens from involved areas and staining and culture for mycobacteriae are essential for diagnosis. Treatment involves antimycobacterial therapy, reduction in immunosuppression and surgery, if indicated. Atypical mycobacterial infections, though currently uncommon, are significant and could prove to be an emerging pathogen in renal transplant recipients in the context of the AIDS epidemic in India.
Alexander
Suceena
S
Department of Nephrology, Christian Medical College, Vellore, Tamil Nadu.
John
George T
GT
Jesudason
Mary
M
Jacob
C K
CK
D000293:Adolescent; D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D006801:Humans; D016030:Kidney Transplantation / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D009165:Mycobacterium Infections, Nontuberculous / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology / Q000473:pathology; D016926:Mycobacterium chelonae / Q000302:isolation & purification; D019907:Mycobacterium fortuitum / Q000302:isolation & purification; D009170:Nontuberculous Mycobacteria / Q000145:classification / Q000302:isolation & purification*
D000900:Anti-Bacterial Agents