title: Transient hypoparathyroidism following thyroidectomy: a prospective study and multivariate analysis of 604 consecutive patients.
abstract: OBJECTIVE
  The purpose of this study was to identify the risk factors for postoperative transient hypoparathyroidism in a group of patients undergoing thyroid surgery.
  
  
  METHODS
  A prospective study was conducted on 604 patients undergoing thyroid surgery.
  
  
  METHODS
  Gender, final diagnosis, extent of resection, biology of pathology, intrathoracic involvement, surgery for recurrent multinodular goiter, and presence and number of parathyroid glands in a surgical specimen were analyzed as risk factors for postoperative transient hypoparathyroidism. The chi-square test and a logistic regression analysis were applied.
  
  
  RESULTS
  On logistic regression analysis, only the extent of surgery constituted an independent variable for transient hypoparathyroidism (P = 0.001).
  
  
  CONCLUSIONS
  The extent of surgery to central and/or lateral neck lymph nodes is responsible for a high rate of transient hypoparathyroidism owing to a high probability of unplanned parathyroidectomy or parathyroid gland devascularization.
authors: ENT Department, S. Orsola-Malpighi Hospital, Bologna University, Bologna, Italy. ocavicchi@libero.it
authors: Ottavio
authors: O
authors: Cavicchi
authors: Ottavio
authors: O
authors: Piccin
authors: Umberto
authors: U
authors: Caliceti
authors: Angelo
authors: A
authors: De Cataldis
authors: Renato
authors: R
authors: Pasquali
authors: Alberto Rinaldi
authors: AR
authors: Ceroni
mesh_terms: D018263:Adenocarcinoma, Follicular / Q000601:surgery; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002291:Carcinoma, Papillary / Q000601:surgery; D002648:Child; D005260:Female; D005500:Follow-Up Studies; D006044:Goiter, Nodular / Q000601:surgery; D006045:Goiter, Substernal / Q000601:surgery; D006111:Graves Disease / Q000601:surgery; D006801:Humans; D007011:Hypoparathyroidism / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D037981:Neck Dissection / Q000009:adverse effects; D016105:Parathyroidectomy / Q000009:adverse effects; D011183:Postoperative Complications; D011446:Prospective Studies; D012008:Recurrence; D012086:Reoperation; D012307:Risk Factors; D013964:Thyroid Neoplasms / Q000601:surgery; D013965:Thyroidectomy / Q000009:adverse effects*