[Farnesoid X receptor (FXR): a novel regulative factor involved in metabolism].
Farnesoid X receptor (FXR), a bile acid receptor, belongs to nuclear hormone receptor super-family. FXR regulates expression of a diversity of target genes controlling bile acid homeostasis and lipid and carbohydrate metabolism. Studies on FXR will help to clarify its potential as a pharmacological target for therapeutic applications in many metabolic diseases.
Zhang
Xiao-Yan
XY
Department of Physiology and Pathophysiology, Peking University Health Science Center, Peking University Diabetes Center, Beijing 100083, China.
Guan
You-Fei
YF
D000818:Animals; D001647:Bile Acids and Salts / Q000378:metabolism*; D005947:Glucose / Q000378:metabolism*; D006801:Humans; D050356:Lipid Metabolism / Q000502:physiology*; D018160:Receptors, Cytoplasmic and Nuclear / Q000502:physiology*; D000099150:Receptor, Farnesoid X-Activated
D001647:Bile Acids and Salts; D005947:Glucose; D018160:Receptors, Cytoplasmic and Nuclear; D000099150:Receptor, Farnesoid X-Activated