title: Quantitative trait loci with additive effects on palatability and fatty acid composition of meat in a Wagyu-Limousin F2 population.
abstract: A whole-genome scan was conducted on 328 F(2) progeny in a Wagyu x Limousin cross to identify quantitative trait loci (QTL) affecting palatability and fatty acid composition of beef at an age-constant endpoint. We have identified seven QTL on five chromosomes involved in lipid metabolism and tenderness. None of the genes encoding major enzymes involved in fatty acid metabolism, such as fatty acid synthase (FASN), acetyl-CoA carboxylase alpha (ACACA), solute carrier family 2 (facilitated glucose transporter) member 4 (SLC2A4), stearoyl-CoA desaturase (SCD) and genes encoding the subunits of fatty acid elongase, was located in these QTL regions. The present study may lead to a better-tasting and healthier product for consumers through improved selection for palatability and lipid content of beef.
authors: U.S. Department of Agriculture-Agricultural Research Service, Miles City, MT 59301, USA. lee.alexander@ars.usda.gov
authors: L J
authors: LJ
authors: Alexander
authors: M D
authors: MD
authors: Macneil
authors: T W
authors: TW
authors: Geary
authors: W M
authors: WM
authors: Snelling
authors: D C
authors: DC
authors: Rule
authors: J A
authors: JA
authors: Scanga
mesh_terms: D000818:Animals; D001823:Body Composition / Q000235:genetics*; D002417:Cattle; D003433:Crosses, Genetic; D005227:Fatty Acids / Q000032:analysis*; D005260:Female; D016678:Genome; D008297:Male; D008460:Meat / Q000032:analysis*; D018895:Microsatellite Repeats / Q000235:genetics; D018482:Muscle, Skeletal / Q000737:chemistry* / Q000378:metabolism; D040641:Quantitative Trait Loci; D013649:Taste / Q000235:genetics*
chemical_list: D005227:Fatty Acids