title: The intestinal mucosa as a reservoir of HIV-1 infection after successful HAART.
abstract: The presence of HIV-1 RNA in distal duodenal mucosa was evaluated in 44 HIV-1-positive patients. HIV-1 RNA was detected in gut tissue in antiretroviral-naive patients with high plasma viral loads, as well as in patients on HAART with plasma viral loads below the limit of detection and in patients on HAART with virological failure. The intestinal mucosa seems to serve as a reservoir poorly influenced by levels of plasma viral load or HAART.
authors: Instituto de Investigaciones Hematológicas, Academia Nacional de Medicina, Buenos Aires, Argentina.
authors: Liliana
authors: L
authors: Belmonte
authors: Martin
authors: M
authors: Olmos
authors: Ana
authors: A
authors: Fanin
authors: Cecilia
authors: C
authors: Parodi
authors: Patricia
authors: P
authors: Baré
authors: Hugo
authors: H
authors: Concetti
authors: Héctor
authors: H
authors: Pérez
authors: Maria Marta E
authors: MM
authors: de Bracco
authors: Pedro
authors: P
authors: Cahn
mesh_terms: D000328:Adult; D023241:Antiretroviral Therapy, Highly Active; D005260:Female; D015658:HIV Infections / Q000188:drug therapy / Q000821:virology*; D015497:HIV-1 / Q000302:isolation & purification*; D006801:Humans; D007413:Intestinal Mucosa / Q000821:virology*; D008297:Male; D012367:RNA, Viral / Q000097:blood*; D016896:Treatment Outcome; D019562:Viral Load
chemical_list: D012367:RNA, Viral