title: Purpura fulminans in a child secondary to Panton-Valentine leukocidin-producing Staphylococcus aureus.
abstract: A case of purpura fulminans (PF) in a child secondary to infection with meticillin-sensitive Staphylococcus aureus (MSSA) encoding the Panton-Valentine leukocidin (PVL) toxin genes is presented. Occasional cases of PF have been documented secondary to S. aureus infection in adults, but, to the authors' knowledge, not in children. Here the first UK case of MSSA-PVL leading to PF is presented.
authors: Department of Clinical Microbiology, Leicester Royal Infirmary, University Hospitals of Leicester NHS Trust, Leicester LE1 5WW, UK.
authors: Abid
authors: A
authors: Hussain
authors: Department of Child Health, Leicester Royal Infirmary, University Hospitals of Leicester NHS Trust, Leicester LE1 5WW, UK.
authors: Gisela
authors: G
authors: Robinson
authors: Department of Clinical Microbiology, Leicester Royal Infirmary, University Hospitals of Leicester NHS Trust, Leicester LE1 5WW, UK.
authors: Joanne
authors: J
authors: Malkin
authors: Department of Child Health, Leicester Royal Infirmary, University Hospitals of Leicester NHS Trust, Leicester LE1 5WW, UK.
authors: Mark
authors: M
authors: Duthie
authors: Staphylococcal Reference Laboratory, Laboratory of Healthcare Associated Infection, Health Protection Agency, Colindale, London NW9 5EQ, UK.
authors: Angela
authors: A
authors: Kearns
authors: Department of Clinical Microbiology, Leicester Royal Infirmary, University Hospitals of Leicester NHS Trust, Leicester LE1 5WW, UK.
authors: Nelun
authors: N
authors: Perera
mesh_terms: D001427:Bacterial Toxins / Q000096:biosynthesis*; D005098:Exotoxins / Q000096:biosynthesis*; D005260:Female; D006801:Humans; D011695:IgA Vasculitis / Q000382:microbiology*; D007223:Infant; D007956:Leukocidins / Q000096:biosynthesis*; D013203:Staphylococcal Infections / Q000150:complications* / Q000382:microbiology*; D013211:Staphylococcus aureus / Q000302:isolation & purification*; D006113:United Kingdom
chemical_list: D001427:Bacterial Toxins; D005098:Exotoxins; D007956:Leukocidins; C078284:Panton-Valentine leukocidin