title: [Recovery of corneal sensitivity in extremely high myopia after laser sub-epithelium keratomileusis].
abstract: OBJECTIVE
  To evaluate the changes in corneal sensitivity following laser epithelial keratomileusis (LASEK) and epiploic laser in situ keratomileusis (Epi-LASIK) in treatment of extremely high myopia.
  
  
  METHODS
  Thirty-seven eyes of 37 patients underwent LASEK and Epi-LASIK to correct myopia, their equivalent sphere ranged from -9.50 DS to -12.50 DS, astigmatism < +/- 1.50 DC. Cornea sensitivity was measured with a Cochet-Bonnet esthesiometer at central part of the cornea. Treated eyes were divided into two groups by different operation methods: Epi-LASIK group and LASEK group. After the operation, each group was divided into two sub-groups according to the eyes with or without obvious epithelium edema.
  
  
  RESULTS
  Obvious epithelium sheet edema happened in 6 eyes after LASEK and 3 eyes among them were due to broken epithelium sheets during the operation. By 2 weeks, 1, 2, 3 and 6 months after Epi-LASIK, corneal sensitivity recovered to 79.31%, 84.49%, 87.92%, 92.24% and 93.98% of preoperative level, respectively. Compare to the Epi-LASIK, cornea sensitivity after LASEK recovered to 69.64%, 78.57%, 83.21%, 85.70% and 87.86% of preoperative level, respectively. The recovery of corneal sensation in LASEK group was slower than that of Epi-LASIK group. The difference between these two groups was statistically significant at 2 weeks after the operation (P < 0.05). In LASEK group, there was a trend towards a great reduction in corneal sensitivity in epithelium edema eyes and the recovery was slower in these eyes. The difference of corneal sensitivity recovery between these two sub-groups was statistically significant (P < 0.05).
  
  
  CONCLUSIONS
  The recovery of corneal sensitivity in extremely high myopia after Epi-LASIK is faster than that after LASEK, and reached to the platform stage by 3 months. The epithelium sheet edema after LASEK affects corneal sensitivity recovery.
authors: Department of Ophthalmology, Eye Ear Nose & Throat Hospital, Fudan University, Shanghai 200031, China.
authors: Hao
authors: H
authors: Zhou
authors: Ren-Yuan
authors: RY
authors: Chu
authors: Ying
authors: Y
authors: Wu
authors: Xing-Tao
authors: XT
authors: Zhou
authors: Jin-Hui
authors: JH
authors: Dai
authors: Pei-Jun
authors: PJ
authors: Yao
mesh_terms: D000328:Adult; D003315:Cornea / Q000502:physiology*; D005260:Female; D006801:Humans; D049008:Keratectomy, Subepithelial, Laser-Assisted; D008297:Male; D009216:Myopia / Q000601:surgery*; D011184:Postoperative Period; D020127:Recovery of Function