[The role of interleukin 10 in allergic inflammation].
Interleukin 10 (IL-10) is a pleiotropic cytokine which shows, under special conditions, some antiinflammatory properties. Among other things it inhibits the synthesis and release of proinflammatory cytokines, preventing persistence of the inflammation. Simultaneously it possesses several proinflammatory properties because of its influence on the B lymphocytes and cytotoxic T cells. It plays crucial role in induction and maintenance of T cells anergy. It was also noticed that some medicines can accomplish their antiinflammatory effects by increasing the production of IL-10.
Tworek
Damian
D
Klinika Pneumonologii i Alergologii Instytutu Medycyny Wewnetrznej UM w Łodzi.
Kuna
Piotr
P
D001402:B-Lymphocytes / Q000378:metabolism; D003888:Desensitization, Immunologic; D006801:Humans; D006967:Hypersensitivity / Q000150:complications* / Q000628:therapy; D007155:Immunologic Factors / Q000378:metabolism; D007249:Inflammation / Q000209:etiology / Q000378:metabolism*; D016753:Interleukin-10 / Q000378:metabolism*; D053701:Receptors, Interleukin-10; D013601:T-Lymphocytes / Q000378:metabolism; D018418:Th2 Cells / Q000378:metabolism*
D007155:Immunologic Factors; D053701:Receptors, Interleukin-10; D016753:Interleukin-10