title: Solid breast mass characterisation: use of the sonographic BI-RADS classification.
abstract: OBJECTIVE
  The aim of this study was to assess the reliability of the sonographic Breast Imaging Reporting and Data System (BI-RADS) classification in differentiating benign from malignant breast masses.
  
  
  METHODS
  A total of 292 female patients with breast masses undergoing biopsy between November 2004 and March 2006 in our department were included in this study. All lesions were classified according to the sonographic BI-RADS lexicon. Sensitivity, specificity, accuracy, positive predictive value (PPV) and negative predictive value (NPV) for the sonographic BI-RADS lexicon and PPV and NPV for each lesion category and each sonographic descriptor were calculated. The chi(2) test and the Fischer exact test were used to evaluate our results.
  
  
  RESULTS
  Univariate analysis showed a significant difference between malignant and benign groups with regard to morphology (p<0.001), horizontal-vertical diameter ratio<1 (p<0.002), orientation (p<0.001), noncircumscribed margins (p<0.001), echogenic halo (p<0.001), hypoechoic pattern (p=0.035), shadowing (p<0.001) and surrounding tissue alterations (p=0.001). The cumulative risk for malignancy was 64 and 10 times higher, respectively, in categories 5 and 4 than in category 3.
  
  
  CONCLUSIONS
  The sonographic BI-RADS lexicon is an important system for describing and classifying breast lesions.
authors: Dipartimento di Bio-Immagini e Scienze Radiologiche, Università Cattolica del Sacro Cuore, Largo A. Gemelli 8, Rome, Italy. mcostantini@rm.unicatt.it
authors: M
authors: M
authors: Costantini
authors: P
authors: P
authors: Belli
authors: C
authors: C
authors: Ierardi
authors: G
authors: G
authors: Franceschini
authors: G
authors: G
authors: La Torre
authors: L
authors: L
authors: Bonomo
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001707:Biopsy, Needle; D001943:Breast Neoplasms / Q000145:classification / Q000175:diagnosis / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D008875:Middle Aged; D011237:Predictive Value of Tests; D012680:Sensitivity and Specificity; D016217:Ultrasonography, Mammary