Early hospital experience with fluphenazine decanoate.
Naturalistic data are reported concerning the first year of hospital use of fluphenazine decanoate. Observations revealed that staff psychiatrists were cautious in their initial use of this product, consistently reserving it for those patients who were very uncooperative about taking oral medications. Outcome of treatment was regarded as satisfactory in only 38% of the patients and a number of unusually severe and prolonged side effects were encountered. A conservative position about the use of depot medications in the treatment of schizophrenia is advocated until further studies of specific target areas for such treatment can be accomplished.
Small
J G
JG
Larue D. Carter Memorial Hospital, Department of Psychiatry, Indiana University School of Medicine, Indianapolis 46202, USA.
Kellams
J
J
D000328:Adult; D014150:Antipsychotic Agents / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D002908:Chronic Disease; D004334:Drug Administration Schedule; D005260:Female; D005476:Fluphenazine / Q000008:administration & dosage / Q000009:adverse effects / Q000031:analogs & derivatives* / Q000627:therapeutic use; D005500:Follow-Up Studies; D006753:Hospital Records; D006801:Humans; D007267:Injections; D008297:Male; D008875:Middle Aged; D010349:Patient Compliance; D010607:Pharmacy Service, Hospital; D012559:Schizophrenia / Q000188:drug therapy*; D016896:Treatment Outcome
D014150:Antipsychotic Agents; C011825:fluphenazine depot; D005476:Fluphenazine