Fluorous tagged small molecule microarrays.
The affinity fluorous interaction between fluorous tagged small molecules and a fluoroalkyl modified glass surface was shown to facilitate the detection of protein-ligand binding interactions in the fabrication and screening of small molecule microarrays.
Nicholson
Rebecca L
RL
Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, UKCB2 1EW.
Ladlow
Mark L
ML
Spring
David R
DR
D001360:Avidin / Q000737:chemistry; D001710:Biotin / Q000737:chemistry; D005466:Fluorocarbons / Q000737:chemistry*; D040081:Protein Array Analysis / Q000379:methods*
D005466:Fluorocarbons; D001360:Avidin; D001710:Biotin