Active cytotoxic reagents based on non-metallocene non-diketonato well-defined C2-symmetrical titanium complexes of tetradentate bis(phenolato) ligands.
Shavit
Michal
M
Department of Inorganic Chemistry, The Hebrew University of Jerusalem, 91904, Jerusalem, Israel.
Peri
Dani
D
Manna
Cesar M
CM
Alexander
Jacob S
JS
Tshuva
Edit Y
EY
D000970:Antineoplastic Agents / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D045744:Cell Line, Tumor; D018360:Crystallography, X-Ray; D003959:Diamines / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D004354:Drug Screening Assays, Antitumor; D005260:Female; D019073:HT29 Cells; D006801:Humans; D008024:Ligands; D009942:Organometallic Compounds / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D010051:Ovarian Neoplasms / Q000188:drug therapy; D010636:Phenols / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D014025:Titanium / Q000737:chemistry*
D000970:Antineoplastic Agents; D003959:Diamines; D008024:Ligands; D009942:Organometallic Compounds; D010636:Phenols; C102815:titanium isopropoxide; D014025:Titanium; C043899:diethoxy-(1-phenyl-1,3-butanedionato)titanium (IV); C020528:titanocene dichloride