title: Substantial rate enhancements of the esterification reaction of phthalic anhydride with methanol at high pressure and using supercritical CO2 as a co-solvent in a glass microreactor.
abstract: The esterification reaction of phthalic anhydride with methanol was performed at different temperatures in a continuous flow glass microreactor at pressures up to 110 bar and using supercritical CO(2) as a co-solvent. The design is such that supercritical CO(2) can be generated inside the microreactor. Substantial rate enhancements were obtained, viz. a 53-fold increase was obtained at 110 bar and 60 degrees C. Supercritical CO(2) as a co-solvent gave rise to a 5400-fold increase (both with respect to batch experiments at 1 bar at the same temperature).
authors: Supramolecular Chemistry and Technology Group, MESA+ Institute for Nanotechnology, University of Twente, PO Box 217, 7500 AE, Enschede, The Netherlands.
authors: F
authors: F
authors: Benito-Lopez
authors: R M
authors: RM
authors: Tiggelaar
authors: K
authors: K
authors: Salbut
authors: J
authors: J
authors: Huskens
authors: R J M
authors: RJ
authors: Egberink
authors: D N
authors: DN
authors: Reinhoudt
authors: H J G E
authors: HJ
authors: Gardeniers
authors: W
authors: W
authors: Verboom