Chronic inflammatory demyelinating polyradiculoneuropathy in chronic graft-versus-host disease following allogeneic hematopoietic stem cell transplantation: case report.
The chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is an unusual but important complication of hematopoietic stem cell transplantation (HSCT) rarely reported to date. We describe a 17-year-old woman with a diagnosis of acute myeloid leukemia due to Fanconi's anemia who was submitted to allogeneic HSCT and developed CIDP as part of graft-versus-host disease. Investigation showed high cerebrospinal fluid protein; electrophysiological studies revealed sensory-motor demyelinating polyradiculoneuropathy; muscle and nerve biopsy were compatible with CIDP.
Lorenzoni
Paulo José
PJ
Neurology and Bone Marrow Transplantation Services, Internal Medicine Department, Hospital de Clínicas, Federal University of Paraná, 80060-900 Curitiba, PR, Brazil.
Scola
Rosana Herminia
RH
Carsten
Ana Lucila Moreira
AL
Trentin
Ana Paula
AP
Teive
Hélio A G
HA
Pasquini
Ricardo
R
Werneck
Lineu C
LC
D000293:Adolescent; D001706:Biopsy; D016026:Bone Marrow Transplantation / Q000009:adverse effects; D005260:Female; D006086:Graft vs Host Disease / Q000209:etiology* / Q000473:pathology; D018380:Hematopoietic Stem Cell Transplantation / Q000009:adverse effects*; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000601:surgery; D009046:Motor Neurons / Q000473:pathology; D020277:Polyradiculoneuropathy, Chronic Inflammatory Demyelinating / Q000209:etiology* / Q000473:pathology; D013127:Spinal Nerves / Q000473:pathology