title: Sodium-bicarbonated mineral water decreases aldosterone levels without affecting urinary excretion of bone minerals.
abstract: AIM To assess in healthy postmenopausal women the influence of consuming sodium-bicarbonated mineral water on postprandial evolution of serum aldosterone and urinary electrolyte excretion.
  
  
  METHODS
  Eighteen postmenopausal women consumed 500 ml of two sodium-bicarbonated mineral waters (sodium-bicarbonated mineral water 1 and sodium-bicarbonated mineral water 2) and a low-mineral water with a standard meal. Postprandial blood samples were taken at 60, 120, 240, 360 and 420 min and aldosterone concentrations were measured. Postprandial urinary minerals were determined.
  
  
  RESULTS
  Urinary and total mineral excretion and urinary mineral concentrations did not differ except for sodium concentration, which was significantly higher with sodium-bicarbonated mineral water 1 than with low-mineral water (P = 0.005). There was a time effect (P = 0.003) on the aldosterone concentration. At 120 min, aldosterone concentrations were lower with sodium-bicarbonated mineral water 1 (P = 0.021) and sodium-bicarbonated mineral water 2 (P = 0.030) compared with low-mineral water.
  
  
  CONCLUSIONS
  Drinking a sodium-rich bicarbonated mineral water with a meal increases urinary sodium concentration excretion without changes in the excretion of potassium and bone minerals.
authors: Department of Metabolism and Nutrition, Instituto del Frío, Spanish Council for Scientific Research (CSIC), Madrid, Spain. sschoppen@fjd.es
authors: Stefanie
authors: S
authors: Schoppen
authors: Ana M
authors: AM
authors: Pérez-Granados
authors: Angeles
authors: A
authors: Carbajal
authors: Beatriz
authors: B
authors: Sarriá
authors: Santiago
authors: S
authors: Navas-Carretero
authors: M
authors: M
authors: Pilar Vaquero
mesh_terms: D000450:Aldosterone / Q000097:blood*; D000704:Analysis of Variance; D015415:Biomarkers / Q000652:urine; D002118:Calcium / Q000652:urine; D002712:Chlorides / Q000652:urine; D018592:Cross-Over Studies; D004435:Eating; D005260:Female; D006801:Humans; D008274:Magnesium / Q000652:urine; D008875:Middle Aged; D008900:Mineral Waters; D008903:Minerals / Q000652:urine*; D010758:Phosphorus / Q000652:urine; D017698:Postmenopause / Q000378:metabolism*; D019518:Postprandial Period; D011188:Potassium / Q000652:urine; D012964:Sodium / Q000652:urine; D017693:Sodium Bicarbonate / Q000008:administration & dosage*
chemical_list: D015415:Biomarkers; D002712:Chlorides; D008900:Mineral Waters; D008903:Minerals; D010758:Phosphorus; D000450:Aldosterone; D017693:Sodium Bicarbonate; D012964:Sodium; D008274:Magnesium; D011188:Potassium; D002118:Calcium