title: Necrotizing fasciitis and gangrene associated with topical herbs in an infant.
abstract: A 4-mo-old Chinese infant developed necrotizing fasciitis and gangrene from a small skin infection on his buttock that was treated with topical herbs. Sequential cultures revealed a number of organisms: Enterococcus species, sensitive to ampicillin, were isolated throughout the course, and coagulasenegative staphylococci replaced gram-negative rods during the later phase of the illness. The infant required prolonged intravenous antibiotic treatment and underwent multiple surgical procedures for debridement and reconstruction. This report serves to alert the public of the importance of avoiding application of unknown topical herbs in children with skin disease. A seemingly small wound, if inappropriately treated, may result in extensive tissue destruction and require extensive surgery.
authors: Department of Paediatrics, Plastic and Reconstructive Surgery, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong. ehon@cuhk.edu.hk
authors: Kam-Lun Ellis
authors: KL
authors: Hon
authors: Kam-Iun Ellis
authors: KI
authors: Hon
authors: Erica
authors: E
authors: Leung
authors: David Andrew
authors: DA
authors: Burd
authors: Alexander K C
authors: AK
authors: Leung
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002081:Buttocks; D003646:Debridement; D019115:Fasciitis, Necrotizing / Q000209:etiology* / Q000628:therapy; D005734:Gangrene / Q000209:etiology / Q000628:therapy; D006801:Humans; D007223:Infant; D008516:Medicine, Chinese Traditional / Q000009:adverse effects* / Q000379:methods; D010946:Plants, Medicinal / Q000009:adverse effects*; D019651:Plastic Surgery Procedures; D012867:Skin / Q000473:pathology; D017192:Skin Diseases, Bacterial / Q000209:etiology* / Q000628:therapy
chemical_list: D000900:Anti-Bacterial Agents