title: Pancreatic ductal adenocarcinoma associated with pancreatic ductal intraepithelial neoplasia: report of a case.
abstract: BACKGROUND
  The presence of pancreatic ductal intraepithelial neoplasia in patients with chronic pancreatitis is a risk factor for development of pancreatic adenocarcinoma.
  
  
  METHODS
  A case of pancreatic ductal adenocarcinoma associated with pancreatic ductal intraepithelial neoplasia was diagnosed in the setting of chronic pancreatitis.
  
  
  RESULTS
  Distal pancreatectomy combined with splenectomy was performed with a diagnosis of pancreatic body carcinoma. Histopathological examination suggested adenocarcinoma associated with pancreatic ductal intraepithelial neoplasia. The tumor was detected in the remaining head of the pancreas, for which a total pancreatectomy was done.
  
  
  CONCLUSIONS
  When a patient with pancreatic ductal intraepithelial neoplasia associated with adenocarcinoma of the pancreas in the setting of chronic pancreatitis is at an increased risk of recurrence in the remaining pancreatic parenchyma, total pancreatectomy may be feasible.
authors: Department of Gastrointestinal Surgery, Govind Ballabh Pant Hospital and Maulana Azad Medical College (Delhi University), New Delhi 110002, India.
authors: Rajkumar
authors: R
authors: Krishnasamy
authors: Shaleen
authors: S
authors: Agarwal
authors: Shivendra
authors: S
authors: Singh
authors: Sunil
authors: S
authors: Puri
authors: Puja
authors: P
authors: Sakhuja
authors: Anil K
authors: AK
authors: Agarwal
mesh_terms: D002278:Carcinoma in Situ / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D021441:Carcinoma, Pancreatic Ductal / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D003937:Diagnosis, Differential; D005500:Follow-Up Studies; D006801:Humans; D010535:Laparoscopy; D007813:Laparotomy / Q000379:methods; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary; D010180:Pancreatectomy / Q000379:methods; D010190:Pancreatic Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D013156:Splenectomy / Q000379:methods; D014057:Tomography, X-Ray Computed