title: Can we achieve Millennium Development Goal 4? New analysis of country trends and forecasts of under-5 mortality to 2015.
abstract: BACKGROUND
  Global efforts have increased the accuracy and timeliness of estimates of under-5 mortality; however, these estimates fail to use all data available, do not use transparent and reproducible methods, do not distinguish predictions from measurements, and provide no indication of uncertainty around point estimates. We aimed to develop new reproducible methods and reanalyse existing data to elucidate detailed time trends.
  
  
  METHODS
  We merged available databases, added to them when possible, and then applied Loess regression to estimate past trends and forecast to 2015 for 172 countries. We developed uncertainty estimates based on different model specifications and estimated levels and trends in neonatal, post-neonatal, and childhood mortality.
  
  
  RESULTS
  Global under-5 mortality has fallen from 110 (109-110) per 1000 in 1980 to 72 (70-74) per 1000 in 2005. Child deaths worldwide have decreased from 13.5 (13.4-13.6) million in 1980 to an estimated 9.7 (9.5-10.0) million in 2005. Global under-5 mortality is expected to decline by 27% from 1990 to 2015, substantially less than the target of Millennium Development Goal 4 (MDG4) of a 67% decrease. Several regions in Latin America, north Africa, the Middle East, Europe, and southeast Asia have had consistent annual rates of decline in excess of 4% over 35 years. Global progress on MDG4 is dominated by slow reductions in sub-Saharan Africa, which also has the slowest rates of decline in fertility.
  
  
  CONCLUSIONS
  Globally, we are not doing a better job of reducing child mortality now than we were three decades ago. Further improvements in the quality and timeliness of child-mortality measurements should be possible by more fully using existing datasets and applying standard analytical strategies.
authors: Institute for Health Metrics and Evaluation at the University of Washington, Seattle, WA 98102, USA. cjlm@u.washington.edu
authors: Christopher J L
authors: CJ
authors: Murray
authors: Thomas
authors: T
authors: Laakso
authors: Kenji
authors: K
authors: Shibuya
authors: Kenneth
authors: K
authors: Hill
authors: Alan D
authors: AD
authors: Lopez
mesh_terms: D046688:Child Mortality / Q000639:trends*; D002675:Child, Preschool; D016208:Databases, Factual; D005544:Forecasting / Q000379:methods*; D006801:Humans; D007223:Infant; D007226:Infant Mortality / Q000639:trends*; D007231:Infant, Newborn; D009937:Organizational Objectives; D014480:United Nations; D014944:World Health Organization