title: Creating a model program for influenza surveillance in California: results from the 2005-2006 influenza season.
abstract: BACKGROUND
  Influenza surveillance is valuable for monitoring trends in influenza-related morbidity and mortality. Using the 2005-2006 influenza season as an example, this paper describes a comprehensive influenza surveillance program used by the California Department of Public Health (CDPH).
  
  
  METHODS
  Data collected from patients evaluated for acute respiratory illness in a given week were reported and summarized the following week, including (1) electronic hospital pneumonia and influenza admission and antiviral usage records from Kaiser Permanente, (2) sentinel provider influenza-like illness (ILI) reports, (3) severe pediatric influenza case reports (e.g., children either hospitalized in intensive care or expired), (4) school clinic ILI evaluations, and (5) positive influenza test results from a network of academic, hospital, commercial, and public health laboratories and the state CDPH Viral and Rickettsial Disease Laboratory.
  
  
  RESULTS
  Influenza activity in California in the 2005-2006 season was moderate in severity; all clinical and laboratory markers rose and fell consistently. Extensive laboratory characterization identified the predominant circulating virus strain as A/California/7/2004(H3N2), which was a component of the 2005-2006 influenza vaccine; 96% of samples tested showed adamantane resistance.
  
  
  CONCLUSIONS
  By using multiple, complementary surveillance methods coupled with a strong laboratory component, the CDPH has developed a simple, flexible, stable, and widely accepted influenza surveillance system that can monitor trends in statewide influenza activity, ascertain the correlation between circulating strains with vaccine strains, and assist with detection of new strain variants. The methods described can serve as a model for influenza surveillance in other states.
authors: Department of Health Services, Viral and Ricksettial Disease Laboratory, California Department of Public Health, 850 Marina Bay Parkway, Richmond, CA 94804, USA. JLouie@dhs.ca.gov
authors: Janice K
authors: JK
authors: Louie
authors: David P
authors: DP
authors: Schnurr
authors: Hugo F
authors: HF
authors: Guevara
authors: Somayeh
authors: S
authors: Honarmand
authors: Michele
authors: M
authors: Cheung
authors: David
authors: D
authors: Cottam
authors: Elaine
authors: E
authors: Yeh
authors: Lauren
authors: L
authors: Wold
authors: Erica J
authors: EJ
authors: Boston
authors: Janet
authors: J
authors: Tang
authors: Kate C
authors: KC
authors: Cummings
authors: Richard M
authors: RM
authors: Donovan
authors: Robert
authors: R
authors: Schechter
authors: Jon
authors: J
authors: Rosenberg
authors: Lawrence J
authors: LJ
authors: Walter
authors: John A
authors: JA
authors: Chapman
authors: Paul R
authors: PR
authors: Brenner
authors: Roger P
authors: RP
authors: Baxter
authors: Carol A
authors: CA
authors: Glaser
mesh_terms: D002140:California / Q000453:epidemiology; D006801:Humans; D007251:Influenza, Human / Q000453:epidemiology* / Q000401:mortality; D029521:Alphainfluenzavirus / Q000302:isolation & purification*; D017146:Models, Organizational; D011159:Population Surveillance / Q000379:methods*; D012621:Seasons