Prevalence and risk factors for gall bladder polyps.
OBJECTIVE
Polyps of gallbladder are tumour-like lesions of this organ. Little has been known about factors associated with the occurrence of gallbladder polyps. We aimed to examine prevalence and factors associated with gallbladder polyps in our region.


METHODS
Prospective clinical study.


METHODS
Kocaeli University Teaching Hospital.


METHODS
Four hundred and thirty two patients were enrolled to the study.


METHODS
Subjects were screened for the presence of any pathological condition for gallbladder by upper abdominal ultrasonography completed a questionnaire, and underwent a physical examination and blood chemistry tests.


RESULTS
Family history of gastrointestinal disease, gallbladder disease and any neoplastic disease and abnormality in HDL-cholesterol levels had most consistent association at univariate analysis. Multivariate logistic regression analysis showed that family history of any gastrointestinal disease and abnormalities of HDL-cholesterol levels were significant.


CONCLUSIONS
Our findings suggest the formation of gallbladder polyps is associated with fat metabolism. Other unknown factors may also influence the formation of this lesion. Relationship between gallbladder polyps and family history of some diseases suggests us to perform some genetic studies.
Cantürk
Z
Z
Department of Gastroenterology, Faculty of Medicine, Kocaeli University, Turkey.
Sentürk
O
O
Cantürk
N Z
NZ
Anik
Y A
YA
D018256:Adenomatous Polyps / Q000000981:diagnostic imaging / Q000453:epidemiology* / Q000235:genetics; D000328:Adult; D000368:Aged; D008076:Cholesterol, HDL / Q000097:blood / Q000172:deficiency; D005223:Fats / Q000378:metabolism; D005260:Female; D005705:Gallbladder Diseases / Q000000981:diagnostic imaging / Q000453:epidemiology* / Q000235:genetics; D005706:Gallbladder Neoplasms / Q000000981:diagnostic imaging / Q000453:epidemiology* / Q000235:genetics; D006306:Health Surveys; D006801:Humans; D007407:Interviews as Topic; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D011446:Prospective Studies; D012307:Risk Factors; D011795:Surveys and Questionnaires; D014421:Turkey / Q000453:epidemiology; D014463:Ultrasonography
D008076:Cholesterol, HDL; D005223:Fats