Motor proteins: trafficking and signaling collide.
Motor proteins carry scaffolding proteins and associated signaling molecules along cytoskeletal tracks to specific cellular destinations. Recent work has shown that the signaling components are not just along for the ride. Rather, they can play an important role in regulating the motor that carries them.
Verhey
Kristen J
KJ
Department of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, Michigan, USA. kjverhey@umich.edu
D000818:Animals; D001370:Axonal Transport; D001692:Biological Transport; D003598:Cytoskeletal Proteins / Q000378:metabolism*; D004330:Drosophila / Q000378:metabolism*; D029721:Drosophila Proteins / Q000378:metabolism*; D048031:JNK Mitogen-Activated Protein Kinases / Q000378:metabolism; D016547:Kinesins / Q000378:metabolism; D020935:MAP Kinase Signaling System; D008870:Microtubules / Q000378:metabolism; D020409:Molecular Motor Proteins / Q000502:physiology*
D003598:Cytoskeletal Proteins; D029721:Drosophila Proteins; D020409:Molecular Motor Proteins; D048031:JNK Mitogen-Activated Protein Kinases; D016547:Kinesins