[Controlled production of active oxygen forms by leukocytes allows prognosis of the body resistance to stress damage].
The authors suggest using chemiluminescent reaction of the patients' blood leukocytes including the stimulation index (SI) for prediction of the body resistance to stress damage (operative stress). It is shown that in chronic cardiac patients (n = 259) SI is initially subnormal. Some of the above patients had critically low SI ( > 0.6). Such patients developed severe immunodependent postoperative complications. To increase the patients' resistance to operative stress and to avoid postoperative complications it is recommended to conduct prophylactic immunocorrecting therapy under SI control.
Temnov
A A
AA
Onishchenko
N A
NA
D000222:Adaptation, Physiological; D006801:Humans; D007962:Leukocytes / Q000378:metabolism*; D018384:Oxidative Stress; D011183:Postoperative Complications; D011379:Prognosis; D017382:Reactive Oxygen Species / Q000378:metabolism*; D013312:Stress, Physiological / Q000097:blood / Q000209:etiology / Q000378:metabolism*
D017382:Reactive Oxygen Species