title: Predisposing factors for early retirement in patients with schizophrenia in Germany.
abstract: Although early retirement causes major changes in the life of schizophrenic patients and is among the major cost factors to be covered by payers, the causes leading to early retirement of schizophrenic patients have not been investigated in detail. Therefore, the objective of this retrospective non-interventional case-control study was to generate hypotheses on predisposing factors for early retirement in schizophrenia. Logistic regression was used to explore potential predisposing parameters with regard to their effect on the outcome early retirement. As the study results indicate, schizophrenia severity, assistance or care in the patient's everyday life, age and antipsychotic treatment with typical antipsychotics are linked to the occurrence of early retirement. Further research should be planned to confirm or refute the hypotheses determined in this retrospective analysis and to determine whether atypical antipsychotics could help to avoid early retirement and to improve the situation of schizophrenic patients.
authors: University of Essen, Essen, Germany.
authors: Reinhard
authors: R
authors: Schnabel
authors: Heiko
authors: H
authors: Friedel
authors: Andreas
authors: A
authors: Erfurth
authors: Matthias
authors: M
authors: Angermayer
authors: Johannes
authors: J
authors: Clouth
authors: Florian
authors: F
authors: Eichmann
mesh_terms: D000328:Adult; D000367:Age Factors; D016022:Case-Control Studies; D015984:Causality; D005240:Feasibility Studies; D005260:Female; D005858:Germany; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D015233:Models, Statistical; D010415:Pensions; D010865:Pilot Projects; D012179:Retirement / Q000191:economics* / Q000706:statistics & numerical data; D012189:Retrospective Studies; D012307:Risk Factors; D012559:Schizophrenia / Q000191:economics* / Q000453:epidemiology; D013997:Time Factors