Vitamin K contents of rodent diets: a review.
Adequate nutrient intake is critical in the maintenance of normal physiologic activity of rodents in biomedical studies. Vitamin K is an essential nutrient in rodent diets and functions as a cofactor for the gamma-carboxylation of various proteins involved in blood coagulation and bone metabolism. Several forms of vitamin K are used in rodent diets, with a shift during the last decade towards the use of phylloquinone, the predominant form in human diets, and a concomitant increase in concentrations. This review summarizes current recommendations for vitamin K in rodent diets relative to our evolving knowledge about this fat-soluble vitamin.
Fu
Xueyan
X
Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA, USA.
Booth
Sarah L
SL
Smith
Donald E
DE
D000821:Animal Feed / Q000032:analysis*; D000822:Animal Husbandry; D000824:Animal Nutritional Physiological Phenomena; D000818:Animals; D000830:Animals, Laboratory / Q000502:physiology*; D051379:Mice; D015394:Molecular Structure; D051381:Rats; D014812:Vitamin K / Q000032:analysis*
D014812:Vitamin K