title: Visual outcome and rehabilitation in a case of bilateral acanthamoeba sclerokeratitis.
abstract: OBJECTIVE
  To report a rare and complicated case of bilateral Acanthamoeba sclerokeratitis (ASK).
  
  
  METHODS
  Case report of a 42-year-old patient who was referred to the Massachusetts Eye and Ear Infirmary 7 months after a history of culture-confirmed bilateral Acanthamoeba polyphaga sclerokeratitis. At the time of referral to the MEEI, he was noted to have iris neovascularization and chronic mydriasis in both eyes. The anterior chambers were shallow, and there were mature cortical cataracts that obscured the posterior pole in both eyes. His visual acuity in both eyes was limited to hand motions.
  
  
  RESULTS
  The patient underwent sequential cataract extraction, penetrating keratoplasty (PK), and yttrium-argon-garnet laser capsulotomy of the right eye over a span of 3 months. This treatment substantially improved the vision in his right eye to 20/400. Cataract extraction surgery and a PK have been scheduled for this patient's left eye in the near future.
  
  
  CONCLUSIONS
  Some patients with ASK and apparently poor visual prognosis can achieve substantial visual improvement after anterior-segment surgery. This report describes the management and outcome of only the second reported case of bilateral ASK in the world.
authors: Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA 02114, USA. Roberto_Pineda@MEEI.HARVARD.EDU
authors: Roberto
authors: R
authors: Pineda
authors: Tolga
authors: T
authors: Kocatürk
authors: Ravinder Dennis
authors: RD
authors: Bhui
mesh_terms: D015823:Acanthamoeba Keratitis / Q000503:physiopathology / Q000534:rehabilitation*; D000328:Adult; D001550:Benzamidines / Q000627:therapeutic use; D001645:Biguanides / Q000627:therapeutic use; D002387:Cataract Extraction; D002701:Chloramphenicol / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D006801:Humans; D015948:Keratoplasty, Penetrating; D053844:Lasers, Solid-State; D007903:Lens Capsule, Crystalline / Q000601:surgery; D008297:Male; D011239:Prednisolone / Q000627:therapeutic use; D011379:Prognosis; D015423:Scleritis / Q000503:physiopathology / Q000534:rehabilitation*; D014792:Visual Acuity / Q000502:physiology*
chemical_list: D001550:Benzamidines; D001645:Biguanides; C031233:polihexanide; C018961:hexamidine; D002701:Chloramphenicol; D011239:Prednisolone