Multiple discharging sinuses: an unusual presentation caused by Absidia corymbifera.
A case of zygomycosis presenting with non-healing multiple discharging sinuses in a diabetic patient is reported here. The debrided tissue on histopathological examination revealed dense infiltration with aseptate fungal hyphae. Potassium hydroxide mount showed hyaline aseptate hyphae suggestive of zygomycosis. On culture, Absidia corymbifera was isolated. The patient responded to surgical debridement and therapy with amphotericin B followed by itraconazole.
Kindo
A J
AJ
Department of Microbiology, Sri Ramachandra Medical College and Research Institute, Chennai - 600 116, India. anupmalakra@yahoo.com
Shams
N R
NR
Srinivasan
V
V
Kalyani
J
J
Mallika
M
M
D020095:Absidia / Q000187:drug effects / Q000302:isolation & purification*; D000666:Amphotericin B / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use; D002921:Cicatrix / Q000209:etiology / Q000473:pathology; D003937:Diagnosis, Differential; D006801:Humans; D017964:Itraconazole / Q000627:therapeutic use; D007871:Leg Ulcer / Q000209:etiology / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D020096:Zygomycosis / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy
D000935:Antifungal Agents; D017964:Itraconazole; D000666:Amphotericin B