Splicing from the outside in.
A new study in this issue of Molecular Cell (Pleiss et al., 2007b) shows that changes in the environment rapidly alter the splicing efficiency of specific pre-mRNAs in yeast.
Yang
Li
L
Department of Genetics and Developmental Biology, University of Connecticut Health Center, 263 Farmington Avenue, Farmington, CT 06030-3301, USA.
Park
Jung
J
Graveley
Brenton R
BR
D000596:Amino Acids / Q000172:deficiency; D000431:Ethanol / Q000633:toxicity; D016681:Genome, Fungal / Q000235:genetics; D009690:Nucleic Acid Conformation; D020411:Oligonucleotide Array Sequence Analysis; D012322:RNA Precursors / Q000737:chemistry / Q000235:genetics; D012326:RNA Splicing / Q000187:drug effects / Q000235:genetics*; D012331:RNA, Fungal / Q000235:genetics; D012441:Saccharomyces cerevisiae / Q000187:drug effects / Q000235:genetics*
D000596:Amino Acids; D012322:RNA Precursors; D012331:RNA, Fungal; D000431:Ethanol