[Racemic and optically active alpha-tocopherol analogues with a modified side chain: synthesis and biological activity].
Information on the synthesis and biological activity of natural and synthetic analogues of alpha-tocopherol with a modified side chain is systematized. These compounds are of interest as vitamin E metabolites, hydrophilic antioxidants, and precursors of drugs with combined pharmacological properties useful in therapy of pathological disorders caused by oxidative stress.
Odinokov
V N
VN
Spivak
A Iu
AIu
Knyshenko
O V
OV
D000818:Animals; D000975:Antioxidants / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D006801:Humans; D015394:Molecular Structure; D018384:Oxidative Stress / Q000187:drug effects; D013237:Stereoisomerism; D013329:Structure-Activity Relationship; D024502:alpha-Tocopherol / Q000031:analogs & derivatives / Q000138:chemical synthesis / Q000494:pharmacology
D000975:Antioxidants; D024502:alpha-Tocopherol