title: Temporal pole signal abnormality on MR imaging in temporal lobe epilepsy with hippocampal sclerosis: a fluid-attenuated inversion-recovery study.
abstract: OBJECTIVE
  To determine the frequency and regional involvement of temporal pole signal abnormality (TPA) in patients with hippocampal sclerosis (HS) using fluid-attenuated inversion-recovery (FLAIR) MR imaging, and to correlate this feature with history.
  
  
  METHODS
  Coronal FLAIR images of the temporal pole were assessed in 120 patients with HS and in 30 normal subjects, to evaluate gray-white matter demarcation.
  
  
  RESULTS
  Ninety (75%) of 120 patients had associated TPA. The HS side made difference regarding the presence of TPA, with a left side prevalence (p=0.04, chi2 test). The anteromedial zone of temporal pole was affected in 27 (30%) out of 90 patients. In 63 (70%) patients the lateral zone were also affected. Patients with TPA were younger at seizure onset (p=0.018), but without association with duration of epilepsy.
  
  
  CONCLUSIONS
  Our FLAIR study show temporal pole signal abnormality in 3/4 of patients with HS, mainly seen on the anteromedial region, with a larger prevalence when the left hippocampus was involved.
authors: Departamento de Diagnóstico por Imagem, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, SP, Brazil.
authors: Henrique
authors: H
authors: Carrete
authors: Nitamar
authors: N
authors: Abdala
authors: Kátia
authors: K
authors: Lin
authors: Luís Otávio
authors: LO
authors: Caboclo
authors: Ricardo Silva
authors: RS
authors: Centeno
authors: Américo Ceiki
authors: AC
authors: Sakamoto
authors: Jacob
authors: J
authors: Szjenfeld
authors: Roberto Gomes
authors: RG
authors: Nogueira
authors: Elza Márcia Targas
authors: EM
authors: Yacubian
mesh_terms: D000293:Adolescent; D000328:Adult; D017668:Age of Onset; D001927:Brain Diseases / Q000453:epidemiology / Q000473:pathology*; D001938:Brazil / Q000453:epidemiology; D016009:Chi-Square Distribution; D004833:Epilepsy, Temporal Lobe / Q000453:epidemiology / Q000473:pathology*; D005260:Female; D007839:Functional Laterality; D006624:Hippocampus / Q000473:pathology*; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D008875:Middle Aged; D012598:Sclerosis; D012815:Signal Processing, Computer-Assisted; D013702:Temporal Lobe / Q000002:abnormalities* / Q000473:pathology*; D013997:Time Factors