title: [Exercise deep venous thrombosis: myth or reality? About three cases of pulmonary embolism in long-distance runners].
abstract: The most frequent manifestation of exercise deep vein thrombosis (DVT) is the one occurring in upper limbs, in some specific and stereotypic conditions, sometimes complicated by pulmonary embolisms. A few cases of lower limbs DVT are reported in athletes. Some pathophysiologic arguments (rheological modifications, parietal lesions and coagulation abnormalities) suggest a link between DVT and exertion, but the causality is sometimes difficult to establish. We report three cases of pulmonary embolism occurring after a prolonged effort of running in trained marathon athletes. To our knowledge, very few similar cases have ever been reported. The possible responsibility of such physical efforts is discussed, as well as other potential cofactors such as coagulation abnormalities and hormonal contraception.
authors: Service de cardiologie A-USCI, hôpital Trousseau, centre hospitalier universitaire de Tours, 37044 Tours cedex.
authors: B
authors: B
authors: Frémont
authors: G
authors: G
authors: Pacouret
authors: A
authors: A
authors: De Labriolle
authors: B
authors: B
authors: Magdelaine
authors: R
authors: R
authors: Puglisi
authors: B
authors: B
authors: Charbonnier
mesh_terms: D020016:Activated Protein C Resistance / Q000150:complications; D000328:Adult; D000925:Anticoagulants / Q000627:therapeutic use; D003278:Contraceptives, Oral, Hormonal / Q000627:therapeutic use; D005165:Factor V / Q000032:analysis; D005169:Factor VIII / Q000032:analysis; D005260:Female; D005268:Femoral Vein / Q000000981:diagnostic imaging; D006801:Humans; D008297:Male; D008875:Middle Aged; D017354:Point Mutation / Q000235:genetics; D011152:Popliteal Vein / Q000000981:diagnostic imaging; D011655:Pulmonary Embolism / Q000209:etiology*; D012307:Risk Factors; D012420:Running; D019851:Thrombophilia / Q000150:complications; D036542:Tomography, Spiral Computed; D014463:Ultrasonography; D020246:Venous Thrombosis / Q000000981:diagnostic imaging / Q000209:etiology*
chemical_list: D000925:Anticoagulants; D003278:Contraceptives, Oral, Hormonal; C095381:factor V Leiden; D005165:Factor V; D005169:Factor VIII