[A reviewing for abusing of ketamine].
Ketamine is a noncompetitive NMDA receptor antagonist and comes into being a new problem of drug abuse. It can cause a certain extent of hallucination, which makes ketamine be abused in the casinos. The paper reviews the pharmacological and toxicology characteristic of Ketamine, the possible physiological mechanism and the methods for detecting Ketamine abuse.
Yang
Ju
J
Department of Forensic Medicine, Medical School of Soochow University, Suzhou 215123, China.
Bian
Shi-zhong
SZ
D000778:Anesthetics, Dissociative / Q000494:pharmacology / Q000633:toxicity; D002540:Cerebral Cortex / Q000187:drug effects; D006801:Humans; D013287:Illicit Drugs; D007649:Ketamine / Q000494:pharmacology* / Q000633:toxicity*; D001523:Mental Disorders / Q000139:chemically induced; D011954:Receptors, Dopamine / Q000187:drug effects; D016194:Receptors, N-Methyl-D-Aspartate / Q000187:drug effects; D015813:Substance Abuse Detection / Q000379:methods; D019966:Substance-Related Disorders / Q000517:prevention & control*
D000778:Anesthetics, Dissociative; D013287:Illicit Drugs; D011954:Receptors, Dopamine; D016194:Receptors, N-Methyl-D-Aspartate; D007649:Ketamine