title: Influenza vaccines and vaccination strategies in birds.
abstract: Although it is well accepted that the present Asian H5N1 panzootic is predominantly an animal health problem, the human health implications and the risk of human pandemic have highlighted the need for more information and collaboration in the field of veterinary and human health. H5 and H7 avian influenza (AI) viruses have the unique property of becoming highly pathogenic (HPAI) during circulation in poultry. Therefore, the final objective of poultry vaccination against AI must be eradication of the virus and the disease. Actually, important differences exist in the control of avian and human influenza viruses. Firstly, unlike human vaccines that must be adapted to the circulating strain to provide adequate protection, avian influenza vaccination provides broader protection against HPAI viruses. Secondly, although clinical protection is the primary goal of human vaccines, poultry vaccination must also stop transmission to achieve efficient control of the disease. This paper addresses these differences by reviewing the current and future influenza vaccines and vaccination strategies in birds.
authors: Avian Virology & Immunology, Veterinary & Agrochemical Research Centre, 99 Groeselenberg, 1180 Brussels, Belgium. thvan@var.fgov.be
authors: Thierry
authors: T
authors: van den Berg
authors: Bénédicte
authors: B
authors: Lambrecht
authors: Sylvie
authors: S
authors: Marché
authors: Mieke
authors: M
authors: Steensels
authors: Steven
authors: S
authors: Van Borm
authors: Michel
authors: M
authors: Bublot
mesh_terms: D000818:Animals; D001717:Birds; D006736:Horses; D006801:Humans; D053124:Influenza A Virus, H5N1 Subtype / Q000276:immunology*; D007252:Influenza Vaccines / Q000008:administration & dosage / Q000145:classification; D005585:Influenza in Birds / Q000276:immunology / Q000517:prevention & control* / Q000821:virology; D007251:Influenza, Human / Q000276:immunology / Q000517:prevention & control / Q000821:virology; D009976:Orthomyxoviridae Infections / Q000276:immunology / Q000517:prevention & control / Q000662:veterinary; D013552:Swine
chemical_list: D007252:Influenza Vaccines