title: Utilization of prenatal diagnosis and termination of pregnancies for the prevention of Down syndrome in Israel.
abstract: BACKGROUND
  The national program for the prevention of Down syndrome includes screening (using the triple test) and invasive diagnostic tests in women at risk for a Down syndrome pregnancy. However, despite the program, the majority of Down syndrome infants are born alive (approximately 1/1000 live births).
  
  
  OBJECTIVE
  To determine whether the relatively high incidence of Down syndrome at birth in Israel is the result of failure of the preventive program or due to informed choices of the mothers.
  
  
  METHODS
  We conducted a retrospective study using the national registry of Down syndrome for the years 1997 and 2004, according to the mothers' religion and place of residence and the reasons for prenatal diagnosis.
  
  
  RESULTS
  Most of the babies affected with Down syndrome are born in religious or traditional conservative communities where termination of pregnancy is usually not an option.
  
  
  CONCLUSIONS
  In a pluralistic society like Israel with its diverse communities and dissimilar religious backgrounds and traditions, the different attitudes concerning utilization of the national program should be respected. It is necessary to tailor different approaches and solutions for the various ethnic and religious communities according to their need.
authors: Public Health Services and Department of Health Information, Ministry of Health, Tel Hashomer, Israel. joelz@cc.huji.ac.il
authors: Joël
authors: J
authors: Zlotogora
authors: Ziona
authors: Z
authors: Haklai
authors: Alex
authors: A
authors: Leventhal
mesh_terms: D000028:Abortion, Induced / Q000706:statistics & numerical data*; D000328:Adult; D002755:Choice Behavior; D004314:Down Syndrome / Q000208:ethnology / Q000517:prevention & control*; D005260:Female; D006801:Humans; D007514:Islam; D007557:Israel / Q000453:epidemiology; D007585:Jews; D011247:Pregnancy; D011296:Prenatal Diagnosis; D012189:Retrospective Studies