title: Cryptococcus neoformans abscess and osteomyelitis in an immunocompetent patient with tuberculous lymphadenitis.
abstract: Infection with Cryptococcus neoformans usually occurs in immunocompromised hosts and may occur in immunocompetent patients. Of all cryptococcal infections, 10-40% of patients have no apparent immune deficiency. Disseminated disease may occur in up to 62% of HIV-seronegative patients with cryptococcosis; however, cryptococcal osteomyelitis is rare. Here, we report an immunocompetent patient with cryptococcal vertebral osteomyelitis and concomitant tuberculous lymphadenitis. The patient received 12 weeks of fluconazole and a 1-year course of anti-tuberculous agents, with complete recovery.
authors: Internal Medicine Services Division, Dhahran Health Center, Saudi Aramco Medical Services Organization, Saudi Aramco, Dhahran, 31311, Saudi Arabia. jaffar.tawfiq@aramco.com
authors: J A
authors: JA
authors: Al-Tawfiq
authors: J
authors: J
authors: Ghandour
mesh_terms: D000038:Abscess / Q000188:drug therapy / Q000382:microbiology*; D000328:Adult; D000935:Antifungal Agents / Q000627:therapeutic use; D000995:Antitubercular Agents / Q000627:therapeutic use; D003453:Cryptococcosis / Q000150:complications* / Q000188:drug therapy / Q000382:microbiology*; D003455:Cryptococcus neoformans / Q000302:isolation & purification; D005260:Female; D015725:Fluconazole / Q000627:therapeutic use; D006801:Humans; D010019:Osteomyelitis / Q000188:drug therapy / Q000382:microbiology*; D013131:Spine / Q000473:pathology; D014388:Tuberculosis, Lymph Node / Q000150:complications*
chemical_list: D000935:Antifungal Agents; D000995:Antitubercular Agents; D015725:Fluconazole