Beneficial effects of jejunal continuity and duodenal food passage after total gastrectomy: a retrospective study of 704 patients.
OBJECTIVE
To evaluate effects of reconstruction procedures on post-operative outcomes and nutritional status after total gastrectomy.


METHODS
The study group comprised 704 consecutive patients with gastric cancer who underwent total gastrectomy between December 1985 and December 2003. Six alimentary reconstruction procedures were performed, including jejunal continuity [Braun, modified Braun I and II and functional jejunal interposition (FJI)] and jejunum transection ["P" Roux-en-Y and "P" jejunal interposition (PJI)]. The duodenal food passage was maintained only by FJI and PJI. We evaluated the time interval to restore food intake after surgery and the incidence of complications and nutritional status for 12 months.


RESULTS
Patients who received jejunum transection required 7.8+/-2.5 days and 11.9+/-4.9 days to restore liquid and semi-liquid food intake, respectively, which reduced to 3.9+/-2.1 days for liquid and 7.9+/-3.9 days for semi-liquid food intake by jejunum continuity. The incidence rates of reflux esophagitis and Roux-en-Y syndrome in patients receiving jejunum transection were 23.5% and 42.4%, respectively, which were decreased to 9.35% and 14.7%, respectively, by jejunal continuity. Furthermore, prognostic nutrition index score of patients receiving the procedures maintaining duodenal food passage (52.9+/-10.9) was higher than that of patients without the duodenal food passage (46.7+/-8.2).


CONCLUSIONS
Jejunal continuity and duodenal food passage showed beneficial effects on clinical outcomes after surgery. Among these six procedures, FJI was the only procedure to combine the benefits of jejunal continuity and maintaining the duodenal food passage, indicating that FJI has potential clinical application to improve the quality of patient's life after total gastrectomy.
Pan
Y
Y
Department of Gastrointestinal Oncology, Tianjin Medical University Cancer Hospital and Institute, Huanhuxi Road, Ti-Yuan-Bei, Hexi District, Tianjin 300060, PR China.
Li
Q
Q
Wang
D C
DC
Wang
J C
JC
Liang
H
H
Liu
J Z
JZ
Cui
Q H
QH
Sun
T
T
Zhang
R P
RP
Kong
D L
DL
Hao
X S
XS
D002681:China / Q000453:epidemiology; D004386:Duodenum / Q000503:physiopathology*; D005247:Feeding Behavior; D005260:Female; D005743:Gastrectomy / Q000379:methods*; D005772:Gastrointestinal Transit / Q000502:physiology*; D006801:Humans; D015994:Incidence; D007583:Jejunum / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D009752:Nutritional Status; D011178:Postgastrectomy Syndromes / Q000453:epidemiology; D019651:Plastic Surgery Procedures; D012189:Retrospective Studies; D013997:Time Factors