CMP-pseudaminic acid is a natural potent inhibitor of PseB, the first enzyme of the pseudaminic acid pathway in Campylobacter jejuni and Helicobacter pylori.
McNally
David J
DJ
National Research Council of Canada-Institute for Biological Sciences, Ottawa ON, K1A 0R6, Canada. david.mcnally@nrc-cnrc.gc.ca
Schoenhofen
Ian C
IC
Houliston
R Scott
RS
Khieu
Nam H
NH
Whitfield
Dennis M
DM
Logan
Susan M
SM
Jarrell
Harold C
HC
Brisson
Jean-Robert
JR
D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000494:pharmacology*; D001665:Binding Sites; D016123:Campylobacter jejuni / Q000187:drug effects* / Q000201:enzymology; D002384:Catalysis; D003568:Cytidine Monophosphate / Q000737:chemistry / Q000494:pharmacology*; D004305:Dose-Response Relationship, Drug; D004791:Enzyme Inhibitors / Q000737:chemistry / Q000494:pharmacology*; D016480:Helicobacter pylori / Q000187:drug effects* / Q000201:enzymology; D009682:Magnetic Resonance Spectroscopy; D012794:Sialic Acids / Q000737:chemistry / Q000378:metabolism; D013400:Sugar Acids / Q000737:chemistry / Q000494:pharmacology*
C513444:5,7-diacetamido-3,5,7,9-tetradeoxynonulosonic acid; D000900:Anti-Bacterial Agents; D004791:Enzyme Inhibitors; D012794:Sialic Acids; D013400:Sugar Acids; D003568:Cytidine Monophosphate