title: Forty-slice MDCT enteroclysis: evaluation after oral administration of isotonic solution in Crohn's disease.
abstract: OBJECTIVE
  The aim of this study was to evaluate the accuracy of multidetector computed tomography (MDCT) enteroclysis after oral hyperhydration with isotonic solution in detecting bowel wall alterations in patients with Crohn's disease.
  
  
  METHODS
  Twenty-eight patients with a diagnosis of Crohn's disease established by ileocolonoscopy and histology were enrolled in the study; 15 patients with negative ileocolonoscopy served as controls. In all cases, MDCT enteroclysis was performed after oral administration of 2,000 ml of isotonic solution and intravenous administration of N-butylscopolamine. Axial, isotropic multiplanar and volume-rendered reconstructions were used to evaluate bowel wall thickness, ulceration, contrast enhancement, extraparietal involvement and possible complications.
  
  
  RESULTS
  MDCT enteroclysis identified the typical signs of Crohn's disease in 26 patients (92.8%), with sensitivity of 92.8%, specificity of 100%, positive predictive value 100% and negative predictive value 75%.
  
  
  CONCLUSIONS
  MDCT enteroclysis after oral hyperhydration with isotonic solution showed a high level of accuracy in detecting small bowel changes in patients with Crohn's disease. It can be considered a safe and effective alternative to conventional radiography and small-bowel spiral computed tomography enema, especially in patients who refuse nasojejunal intubation.
authors: Sezione di Scienze Radiologiche del Dipartimento di Biotecnologie Mediche e Medicina Legale, Via del Vespro 127, Palermo, Italy. Giuseppe.lore12@tin.it
authors: G
authors: G
authors: Lo Re
authors: M
authors: M
authors: Galia
authors: T V
authors: TV
authors: Bartolotta
authors: G
authors: G
authors: Runza
authors: A
authors: A
authors: Taibbi
authors: R
authors: R
authors: Lagalla
authors: M
authors: M
authors: De Maria
authors: M
authors: M
authors: Midiri
mesh_terms: D000284:Administration, Oral; D000328:Adult; D002400:Cathartics / Q000008:administration & dosage; D003287:Contrast Media; D003424:Crohn Disease / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D007421:Intestine, Small / Q000000981:diagnostic imaging*; D007479:Iopamidol / Q000031:analogs & derivatives; D007552:Isotonic Solutions / Q000008:administration & dosage; D008297:Male; D011092:Polyethylene Glycols / Q000008:administration & dosage*; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed
chemical_list: D002400:Cathartics; D003287:Contrast Media; D007552:Isotonic Solutions; C057937:iomeprol; D011092:Polyethylene Glycols; D007479:Iopamidol