title: [Cervical lymph nodes metastases in patients with differentiated thyroid cancer].
abstract: Loco-regional recurrences of the differentiated thyroid cancer have been reported to be located in cervical lymph nodes in 60-75% of cases. The widespread use of neck ultrasonography (US) during the follow-up of patients with papillary thyroid carcinoma (PTC) has led to the discovery of small cervical lymph nodes (LN). Although US has a high sensitivity for diagnosing LN, fine needle aspiration biopsy (FNA) and measurement of thyroglobulin in fine needle aspirates (FNA-Tg) have proven to be invaluable tools. The aim of this paper is to review the importance of the early diagnosis of lymph node metastases in the follow-up of patients with differentiated thyroid cancer.
authors: Divisão de Endocrinologia, Escola Paulista de Medicina, UNIFESP, São Paulo, SP, Brazil. rosapaula@uol.com.br
authors: Rosa Paula M
authors: RP
authors: Biscolla
mesh_terms: D014408:Biomarkers, Tumor / Q000097:blood; D044963:Biopsy, Fine-Needle; D002291:Carcinoma, Papillary / Q000556:secondary*; D042241:Early Diagnosis; D006258:Head and Neck Neoplasms / Q000097:blood / Q000556:secondary*; D006801:Humans; D008198:Lymph Nodes / Q000000981:diagnostic imaging / Q000473:pathology; D008207:Lymphatic Metastasis; D009333:Neck; D009364:Neoplasm Recurrence, Local / Q000097:blood / Q000473:pathology; D013954:Thyroglobulin / Q000097:blood; D013964:Thyroid Neoplasms / Q000473:pathology*; D014463:Ultrasonography
chemical_list: D014408:Biomarkers, Tumor; D013954:Thyroglobulin