Differentiated adamantinoma: a case report and review of literature.
Adamantinoma of the long bones are uncommon, slow growing tumors with a predilection for the tibia. A special rare variant known as the osteofibrous dysplasia-like adamantinoma or differentiated adamantinoma is thought to be a precursor of the classic adamantinoma. We report a case in a 24 year old female who presented with pain and lytic lesion of the left tibia. Microscopy showed a tumor composed predominantly of osteofibrous dysplasia-like areas with focal cytokeratin positive epithelial islands. This case is highlighted because of its rarity, its association with good prognosis and possible misdiagnosis as osteofibrous dysplasia.
Mathew
Mary
M
Department of Pathology, Kasturba Medical College, Manipal, Karnataka. marypathkmc@yahoo.com
Joseph
Benjamin
B
D050398:Adamantinoma / Q000175:diagnosis* / Q000473:pathology; D000328:Adult; D001859:Bone Neoplasms / Q000175:diagnosis* / Q000473:pathology; D005260:Female; D005357:Fibrous Dysplasia of Bone / Q000473:pathology; D006801:Humans; D013977:Tibia / Q000473:pathology*