title: Changes in serum eosinophil cationic protein levels after exercise challenge in asthmatic children.
abstract: The aim of the present study was to assess the relationship between serum eosinophil cationic protein levels and the severity of exercise-induced bronchoconstriction in asthmatic children. The 48 asthmatic children were divided into exercise-induced bronchoconstriction group and non-exercise-induced bronchoconstriction group. In the exercise-induced bronchoconstriction group, the post-exercise serum eosinophil cationic protein levels were significantly increased as compared with the pre-exercise serum eosinophil cationic protein levels. These results suggested that eosinophil cationic protein may serve as a possible contributor to the pathophysiology of exercise-induced bronchoconstriction in asthmatic children.
authors: First Department of Internal Medicine, School of Medicine, Kyorin University, Tokyo, Japan.
authors: Chia-Chang
authors: CC
authors: Hsieh
authors: Hajime
authors: H
authors: Goto
authors: Hiroyuki
authors: H
authors: Kobayashi
authors: Wen-Chi
authors: WC
authors: Chow
authors: Wen-Huang
authors: WH
authors: Peng
authors: Ren-Bin
authors: RB
authors: Tang
mesh_terms: D000293:Adolescent; D001249:Asthma / Q000503:physiopathology*; D001250:Asthma, Exercise-Induced / Q000503:physiopathology; D015415:Biomarkers / Q000097:blood; D002648:Child; D047150:Eosinophil Cationic Protein / Q000097:blood*; D005260:Female; D006801:Humans; D008297:Male; D011446:Prospective Studies
chemical_list: D015415:Biomarkers; D047150:Eosinophil Cationic Protein