Acute hemorrhagic pancreatitis due to the use of valproic acid in a child.
Acute pancreatitis is rarely seen in children, and it is often drug induced. Valproic acid (VPA) is one of the most widely used anticonvulsants for children all over the world. We present 11-year-old boy developing pancreatitis after 6 months of therapy with VPA. The symptoms of pancreatitis subsided within 2 weeks after discontinuation of VPA. It seems that the prognosis of VPA-associated acute pancreatitis depends on early diagnosis, timely withdrawal of the offending agent and the treatment.
Ozaydin
Eda
E
Department of Pediatrics, Ankara Diskapi Children's Hospital, Turkey. eozaydin2001@yahoo.com
Yükselgüngör
Handan
H
Köse
Gülşen
G
D000208:Acute Disease; D000927:Anticonvulsants / Q000009:adverse effects* / Q000627:therapeutic use; D002648:Child; D004829:Epilepsy, Generalized / Q000150:complications / Q000188:drug therapy; D006470:Hemorrhage / Q000139:chemically induced* / Q000473:pathology; D006801:Humans; D008607:Intellectual Disability / Q000150:complications; D007813:Laparotomy; D008297:Male; D010195:Pancreatitis / Q000139:chemically induced* / Q000473:pathology; D014635:Valproic Acid / Q000009:adverse effects* / Q000627:therapeutic use
D000927:Anticonvulsants; D014635:Valproic Acid