title: CREx: inferring genomic rearrangements based on common intervals.
abstract: CONCLUSIONS
  We present the web-based program CREx for heuristically determining pairwise rearrangement events in unichromosomal genomes. CREx considers transpositions, reverse transpositions, reversals and tandem-duplication-random-loss (TDRL) events. It supports the user in finding parsimonious rearrangement scenarios given a phylogenetic hypothesis. CREx is based on common intervals, which reflect genes that appear consecutively in several of the input gene orders.
  
  
  BACKGROUND
  CREx is freely available at http://pacosy.informatik.uni-leipzig.de/crex
authors: Parallel Computing and Complex Systems Group, University of Leipzig, Fraunhofer Institute IZI, Leipzig, Germany. merkle@informatik.uni-leipzig.de
authors: Matthias
authors: M
authors: Bernt
authors: Daniel
authors: D
authors: Merkle
authors: Kai
authors: K
authors: Ramsch
authors: Guido
authors: G
authors: Fritzsch
authors: Marleen
authors: M
authors: Perseke
authors: Detlef
authors: D
authors: Bernhard
authors: Martin
authors: M
authors: Schlegel
authors: Peter F
authors: PF
authors: Stadler
authors: Martin
authors: M
authors: Middendorf
mesh_terms: D000465:Algorithms; D002874:Chromosome Mapping / Q000379:methods*; D003196:Computer Graphics; D015321:Gene Rearrangement / Q000235:genetics*; D017422:Sequence Analysis, DNA / Q000379:methods*; D012984:Software; D014584:User-Computer Interface