title: Serotypes and antimicrobial susceptibilities of Streptococcus pneumoniae isolated from hospitalized patients in Thailand.
abstract: Two hundred seven Streptococcus pneumoniae isolates were obtained from patients admitted to Siriraj Hospital. One hundred two, and 105 isolates were from sterile sites and non-sterile sites, respectively. They were serotyped by Quellung reaction with specific antisera from Statens Serum Institut; 81.6% of these pneumococci were typeable. These serotypes were included in the 23-valent pneumococcal polysaccharide vaccine. The five most common serotypes were serotype 6 (22.5%), followed by serotype 23 (18.9%), serotype 19 (16.6%), serotype 3 (7.7%) and serotype 11 (5.3%). Among typeable pneumococci (169 isolates), 52.7% were from sterile sites and 47.3% were from non-sterile sites. Serotypes 6, 23 and 19 were the predominant serotypes isolated from sterile sites. Of the 9 drugs tested, pneumococcal isolates were sensitive to ofloxacin (99%), ciprofloxacin (81.5%), meropenem (80%), imipenem (66.5%), ceftriaxone (65%), cefotaxime (63%), erythromycin (58%), penicillin (48%), and trimethoprim-sulfamethoxazole (34.5%).
authors: Department of Microbiology, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand.
authors: Somporn
authors: S
authors: Srifeungfung
authors: Kulkanya
authors: K
authors: Chokephaibulkit
authors: Chanwit
authors: C
authors: Tribuddharat
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D006801:Humans; D007297:Inpatients; D011008:Pneumococcal Infections / Q000188:drug therapy* / Q000503:physiopathology; D012703:Serotyping; D013296:Streptococcus pneumoniae / Q000187:drug effects* / Q000302:isolation & purification*; D013785:Thailand; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents