Organocatalytic asymmetric "anti-Michael" reaction of beta-ketoesters.
The first organocatalytic "anti-Michael" reaction of cyclic-beta-ketoesters to unsaturated double bonds is described in a highly asymmetric version leading to the synthesis of alpha,alpha'-disubstituted branched double bonds as optically active Baylis-Hillman-like adducts.
Alemán
José
J
Danish National Research Foundation: Center for Catalysis, Department of Chemistry, Aarhus University, DK-8000, Aarhus C, Denmark.
Reyes
Efraím
E
Richter
Bo
B
Overgaard
Jacob
J
Jørgensen
Karl Anker
KA