title: Desensitizing efficacy of a new toothpaste containing 5.5% potassium citrate: a 4-week clinical study.
abstract: OBJECTIVE
  To evaluate the desensitizing capabilities of a new toothpaste containing 5.5% potassium citrate (Colgate Sensitive Multi Protection Toothpaste) to another toothpaste containing 3.75% potassium chloride (Sensodyne Total Care F Toothpaste).
  
  
  METHODS
  A 4-week clinical study was conducted in 75 subjects at the University of Rome, at Tor Vergata, in Rome, Italy, using a double blind, stratified, two treatment design. Tactile sensitivity as well as air blast sensitivity assessment was used to compare the efficacy of the two products.
  
  
  RESULTS
  There was no statistically significant difference in tactile sensitivity scores and air blast sensitivity scores between the tested toothpastes at baseline, 2 weeks and 4 weeks. Both toothpastes provided statistically significant improvement in tactile sensitivity scores and air blast sensitivity scores after 2 weeks of use and 4 weeks of use as compared to baseline scores.
authors: School of Dental Hygiene, University of Rome at Tor Vergata, Italy.
authors: Rafaella
authors: R
authors: Docimo
authors: Luigi
authors: L
authors: Montesani
authors: Paolo
authors: P
authors: Maturo
authors: Micaela
authors: M
authors: Costacurta
authors: Martina
authors: M
authors: Bartolino
authors: William
authors: W
authors: DeVizio
authors: Yun Po
authors: YP
authors: Zhang
authors: Serge
authors: S
authors: Dibart
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000700:Analgesics / Q000627:therapeutic use*; D045424:Complex Mixtures / Q000737:chemistry / Q000627:therapeutic use; D003807:Dentin Sensitivity / Q000188:drug therapy*; D004338:Drug Combinations; D005260:Female; D005459:Fluorides / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged; D009566:Nitrates / Q000627:therapeutic use; D010710:Phosphates / Q000627:therapeutic use; D011189:Potassium Chloride / Q000627:therapeutic use*; D019357:Potassium Citrate / Q000627:therapeutic use*; D017680:Potassium Compounds / Q000737:chemistry / Q000627:therapeutic use*; D014100:Toothpastes / Q000737:chemistry / Q000627:therapeutic use*
chemical_list: D000700:Analgesics; D045424:Complex Mixtures; D004338:Drug Combinations; D009566:Nitrates; D010710:Phosphates; D017680:Potassium Compounds; C097427:Sensodyne; D014100:Toothpastes; C444700:colgate sensitive; D011189:Potassium Chloride; D019357:Potassium Citrate; D005459:Fluorides