Natural killer T cells: a bridge to tolerance or a pathway to rejection?
Over the past 20 years, natural killer T (NKT) cells have been shown to play an important role in both innate and adaptive immune responses. In this review, the potential role of NKT cells in transplantation will be discussed, particularly their role in rejection and the induction of a state of tolerance.
Jukes
John-Paul
JP
Transplantation Research Immunology Group, Nuffield Department of Surgery, University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom. john-paul.jukes@nds.ox.ac.uk
Wood
Kathryn J
KJ
Jones
Nick D
ND
D006084:Graft Rejection / Q000276:immunology*; D006801:Humans; D007108:Immune Tolerance; D007694:Killer Cells, Natural / Q000276:immunology*; D016377:Organ Transplantation; D013601:T-Lymphocytes / Q000276:immunology*