title: A case of oral geotrichosis caused by Geotrichum capitatum in an old patient.
abstract: Geotrichosis is an uncommon fungal infection. Geotrichum capitatum is commonly acknowledged as an opportunistic fungal pathogen that causes systemic geotrichosis in immunocompromised patients, especially patients with acute leukemia and severe neutropenia. Here, we report a case of oral geotrichosis caused by G. capitatum in an old patient with no hematological malignancies. Fungal cells were detected in clinical specimens obtained with oral swabs using the KOH technique. Yeast colonies with peripheral hairs were exclusively isolated as fungi from the oral mucosa and feces of the patient. The isolates were identified as G. capitatum by morphological findings, sugar-assimilation tests, and the nucleotide sequences of the ITS regions of the rDNA. Effective treatment of the patient was achieved with amphotericin B syrup in accord with the results of in vitro susceptibility tests. G. capitatum should be recognized as a fungal pathogen involved in superficial infections of older persons, as should Candida spp., even in the absence of hematological malignancies.
authors: Department of Dermatology, Nagoya Graduate School of Medicine, Aichi 466-8550, Japan.
authors: Hisao
authors: H
authors: Hattori
authors: Chisa
authors: C
authors: Inoue
authors: Yasushi
authors: Y
authors: Tomita
authors: Toshio
authors: T
authors: Kanbe
mesh_terms: D000369:Aged, 80 and over; D000666:Amphotericin B / Q000627:therapeutic use; D005847:Geotrichosis / Q000175:diagnosis* / Q000188:drug therapy; D005848:Geotrichum / Q000302:isolation & purification*; D006801:Humans; D008297:Male; D009055:Mouth / Q000382:microbiology*
chemical_list: D000666:Amphotericin B