Kikuchi's disease: an unusual presentation and a therapeutic challenge.
Kikuchi's disease, or necrotizing histiocytic lymphadenitis, is a rare disease that presents predominantly in young women in their 20s and 30s from the Far East. Our case depicts an African-American male, in his sixth decade of life, presenting with Kikuchi's disease, making our case unusual. The clinical presentation, together with laboratory and pathological tests described here, specifically the utilization of immunohistochemistry, aid in establishing a diagnosis. We advocate the use of steroids as symptomatic therapy and provide a novel and successful therapeutic regimen. We do not recommend antibiotic therapy until an infectious etiology is confirmed.
Mahmood
Ali
A
New York Methodist Hospital, New York, NY, USA. StrikerMD@hotmail.com
Mir
Rabia
R
Salama
Salama R
SR
Miarrostami
Rameen M
RM
Lapidus
Claudia
C
Pujol
Fernando
F
D020042:Histiocytic Necrotizing Lymphadenitis / Q000175:diagnosis* / Q000188:drug therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D013256:Steroids / Q000627:therapeutic use*; D016896:Treatment Outcome
D013256:Steroids