title: A comparison of mental health hospital admissions in a cohort of heroin users prior to and after rapid opiate detoxification and oral naltrexone maintenance.
abstract: Mental health (MH) hospital admissions were investigated in a cohort (N=1184) of heroin dependent persons using linked health records. All MH in-patient admissions were extracted 36 months before to 36 months after commencing rapid opioid detoxification (ROD) and oral naltrexone. Results show that the incidence rate ratio (IRR) of drug-related and other MH admissions peaked in the 3 months immediately prior to treatment. All categories subsequently declined to baseline levels by 36 months following treatment. The authors conclude that treatment for heroin dependence reduces risk of MH admissions.
authors: School of Psychiatry and Clinical Neurosciences, University of Western Australia, Crawley, Western Australia.
authors: D E
authors: DE
authors: Arnold-Reed
authors: P
authors: P
authors: O'Neil
authors: C D J
authors: CD
authors: Holman
authors: M K
authors: MK
authors: Bulsara
authors: C
authors: C
authors: Rodiguez
authors: G
authors: G
authors: Gawthorne
authors: R J
authors: RJ
authors: Tait
authors: G K
authors: GK
authors: Hulse
mesh_terms: D000284:Administration, Oral; D000328:Adult; D015331:Cohort Studies; D005260:Female; D006556:Heroin Dependence / Q000188:drug therapy* / Q000453:epidemiology* / Q000534:rehabilitation; D006760:Hospitalization / Q000706:statistics & numerical data* / Q000639:trends; D006801:Humans; D015994:Incidence; D008297:Male; D008498:Medical Record Linkage; D001523:Mental Disorders / Q000453:epidemiology / Q000628:therapy; D009271:Naltrexone / Q000008:administration & dosage / Q000627:therapeutic use*; D009292:Narcotic Antagonists / Q000008:administration & dosage / Q000627:therapeutic use*; D012307:Risk Factors; D016896:Treatment Outcome; D014904:Western Australia / Q000453:epidemiology
chemical_list: D009292:Narcotic Antagonists; D009271:Naltrexone