title: Nasal cavity paraganglioma with malignant transformation: a case report.
abstract: BACKGROUND
  In this report, we describe a young woman with a nasal cavity paraganglioma with malignant transformation.
  
  
  RESULTS
  A 23-year-old woman presented with frequent right-sided epistaxis. Physical examination revealed a pedunculated mass originating from the right superior turbinate and filling the posterior nasal cavity. The endoscopically removed mass was composed of a reddish anterior portion and a white, flesh-looking posterior portion, the latter comprising the majority of the tumor. Histologically, the anterior portion showed a paraganglioma and the posterior portion showed a separate malignant lesion simulating Ewing's sarcoma/PNET. She underwent wide endoscopic excision including the site of tumor origin and has been followed up for 3 years without any evidence of disease recurrence.
  
  
  CONCLUSIONS
  This is a rare case of nasal cavity paraganglioma that had transformed into a malignant tumor.
authors: Department of Otorhinolaryngology, Seoul National University Boramae Hospital, 425 Dongjak-gu, Shindaebang-dong, Seoul, South Korea. hrjin@paran.com
authors: Hong-Ryul
authors: HR
authors: Jin
authors: Ok-Jun
authors: OJ
authors: Lee
authors: Youngjin
authors: Y
authors: Ahn
mesh_terms: D000328:Adult; D014408:Biomarkers, Tumor / Q000032:analysis; D002471:Cell Transformation, Neoplastic / Q000473:pathology*; D003937:Diagnosis, Differential; D004724:Endoscopy; D004844:Epistaxis / Q000209:etiology; D005260:Female; D006801:Humans; D009296:Nasal Cavity / Q000473:pathology* / Q000601:surgery; D018242:Neuroectodermal Tumors, Primitive / Q000473:pathology / Q000601:surgery; D009669:Nose Neoplasms / Q000473:pathology* / Q000601:surgery; D010235:Paraganglioma / Q000473:pathology* / Q000601:surgery; D009418:S100 Proteins / Q000032:analysis; D012512:Sarcoma, Ewing / Q000473:pathology / Q000601:surgery; D014420:Turbinates / Q000473:pathology* / Q000601:surgery
chemical_list: D014408:Biomarkers, Tumor; D009418:S100 Proteins