TandTRAQ: an open-source tool for integrated protein identification and quantitation.
Integrating qualitative protein identification with quantitative protein analysis is non-trivial, given incompatibility in output formats. We present TandTRAQ, a standalone utility that integrates results from i-Tracker, an open-source iTRAQ quantitation program with the search results from X?Tandem, an open-source proteome search engine. The utility runs from the command-line and can be easily integrated into a pipeline for automation.


BACKGROUND
The TandTRAQ Perl scripts are freely available for download at http://www.ohsucancer.com/isrdev/tandtraq/
Laderas
Ted
T
Informatics Shared Resource, OHSU Cancer Institute, Oregon Health & Science University, Portland, Oregon 97212, USA. laderast@ohsu.edu
Bystrom
Cory
C
McMillen
Debra
D
Fan
Guang
G
McWeeney
Shannon
S
D000465:Algorithms; D003628:Database Management Systems; D030562:Databases, Protein; D016247:Information Storage and Retrieval / Q000379:methods*; D011381:Programming Languages; D011506:Proteins / Q000737:chemistry*; D016415:Sequence Alignment / Q000379:methods; D020539:Sequence Analysis, Protein / Q000379:methods*; D012984:Software; D018511:Systems Integration
D011506:Proteins