Radical damage involving sulfur-containing enzymes and membrane lipids.
Free radicals induce protein modifications, often associated to many biological phenomena. This mini-review overviews the approaches we have used to elucidate the radical-induced damages on sulfur-containing enzymes, such as ribonuclease and lysozyme, and the possible post-translational mechanism of the damage to another cell compartment, such as lipid domain.
Torreggiani
Armida
A
Istituto I.S.O.F., Consiglio Nazionale delle Ricerche, Via P. Gobetti 101, 40129 Bologna, Italy. torreggiani@isof.cnr.it.
Tamba
Maurizio
M
Ferreri
Carla
C
D004798:Enzymes / Q000378:metabolism*; D005609:Free Radicals / Q000378:metabolism*; D005720:Gamma Rays; D008563:Membrane Lipids / Q000378:metabolism*; D012996:Solutions; D013455:Sulfur / Q000378:metabolism*
D004798:Enzymes; D005609:Free Radicals; D008563:Membrane Lipids; D012996:Solutions; D013455:Sulfur