Advanced multifocal tuberculous spondylitis without disk involvement and with multidrug-resistant bacilli.
In this brief report, we describe a 23-year-old immunocompetent Nigerian patient with extensive multifocal tuberculous spondylitis without disk involvement. Cultures of sputum samples and biopsy samples from the L4 vertebra were positive for tuberculosis; drug-susceptibility testing of the isolates revealed multidrug resistance. Treatment with second-line drugs resulted in an excellent interim outcome after 6 months, without the need for surgical intervention.
Neher
Albert
A
Asklepios Professional Clinic München-Gauting, Centre for Pneumology and Thorax Surgery, Teaching Hospital of the Ludwig-Maximilians-University, Gauting, Germany. a.neher@asklepios.com
Kopp
Werner
W
Berna
Gabriele
G
Frank
Johannes
J
Kohlhäufl
Martin
M
D000328:Adult; D000995:Antitubercular Agents / Q000627:therapeutic use; D001706:Biopsy; D024901:Drug Resistance, Multiple, Bacterial; D006801:Humans; D008159:Lumbar Vertebrae / Q000382:microbiology / Q000473:pathology; D008297:Male; D008826:Microbial Sensitivity Tests; D009169:Mycobacterium tuberculosis / Q000187:drug effects* / Q000302:isolation & purification; D013166:Spondylitis / Q000188:drug therapy / Q000382:microbiology* / Q000473:pathology; D013183:Sputum / Q000382:microbiology; D016896:Treatment Outcome; D018088:Tuberculosis, Multidrug-Resistant / Q000188:drug therapy / Q000382:microbiology* / Q000473:pathology; D014394:Tuberculosis, Osteoarticular / Q000188:drug therapy / Q000382:microbiology* / Q000473:pathology
D000995:Antitubercular Agents