[Study on the influencing factors to cerebral stroke in a region with high prevalence rate of hypertension].
OBJECTIVE
To investigate the influencing factors on cerebral stroke in Zhangwu county, Liaoning province, a region with high hypertension prevalence rate.


METHODS
By cluster sampling method, 5208 adults ( > 18y. ) from 11 villages of 6 towns were registered. General information, common risk factors of cerebral stroke about these persons was recorded. Blood pressure together with several biochemistry indicators was determined. Data were analyzed by SPSS 10.0 software.


RESULTS
Standardized prevalence of cerebral stroke in this region was 3.10%, and the difference between males and females was significant. Prevalence rate was increasing with age. Multiple-factor analysis revealed that the incidence rate of cerebral stroke was related to high blood pressure, high diastolic pressure, pulse pressure, age, high-density lipoprotein cholesterol (HDL-C) and low-DL-C (LDL-C) level with OR values of 95% CI as 2.958 (1.783-4.907), 2.803 (1.934-4.062), 1.154 (1.056-1.261), 1.080 (1.063-1.097), 0.390 (0.235-0.647) and 1.422 (1.008-2.006) respectively.


CONCLUSIONS
High blood pressure, in particular high diastolic pressure, pulse pressure and LDL-C level were main risk factors of cerebral stroke in Zhangwu countryside. However, HDL-C level was a protective factor. No new risk factors were discovered.
Teng
Wei-yu
WY
Department of Neurology, The First Affiliated Hospital of Chinese Medical University, Shenyang 110001, China.
Wang
Hai-long
HL
Shi
Jing-pu
JP
Fu
Ling-yu
LY
Li
Hui
H
Dong
Wei
W
Dong
Ya-luo
YL
Zhou
Bo
B
Zhao
Feng
F
Wang
Wen-li
WL
D000328:Adult; D000368:Aged; D001794:Blood Pressure / Q000502:physiology; D002681:China / Q000453:epidemiology; D008076:Cholesterol, HDL / Q000097:blood; D008078:Cholesterol, LDL / Q000097:blood; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000453:epidemiology*; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D020521:Stroke / Q000097:blood / Q000453:epidemiology* / Q000209:etiology; D055815:Young Adult
D008076:Cholesterol, HDL; D008078:Cholesterol, LDL