Cucurbitane and hexanorcucurbitane glycosides from the fruits of Cucurbita pepo cv dayangua.
Phytochemical investigation of the fruits of Cucurbita pepo cv dayangua has led to the isolation of two cucurbitane glycosides: cucurbitacin L 2-O-beta-D-glucopyranoside (1), cucurbitacin K 2-O-beta-D-glucopyranoside (2) and two hexanorcucurbitane glycosides: 2,16-dihydroxy-22,23,24,25,26,27-hexanorcucurbit-5-en-11,20-dione 2-O-beta-D-glucopyranoside (3) and 16-hydroxy-22,23,24,25,26,27-hexanorcucurbit-5-en-11,20-dione 3-O-alpha-L-rhamnopyranosyl-(1 --> 2)-beta-D-glucopyranoside (4). Compounds 1, 2 and 3 were isolated from Cucurbita genus for the first time, while compound 4 is a new one. Their structures were determined on the basis of chemical and spectroscopic evidence.
Wang
Da-Cheng
DC
School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shengyang, China.
Pan
Hong-Yu
HY
Deng
Xu-Ming
XM
Xiang
Hua
H
Gao
Hui-Yuan
HY
Cai
Hui
H
Wu
Li-Jun
LJ
D002236:Carbohydrate Conformation; D028464:Cucurbita / Q000737:chemistry*; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification*; D009682:Magnetic Resonance Spectroscopy; D021241:Spectrometry, Mass, Electrospray Ionization; D013055:Spectrophotometry, Infrared; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification*
D006027:Glycosides; D014315:Triterpenes; C514277:cucurbitane