title: Contemporary prostate biopsy complication rates in community-based urology practice.
abstract: OBJECTIVE
  To evaluate whether the increased number of rectal perforations associated with contemporary transrectal ultrasound-guided, 12-core prostate biopsy, with a periprostatic block, is associated with a greater rate of postprocedural complications.
  
  
  METHODS
  We prospectively studied 1000 patients undergoing contemporary transrectal ultrasound-guided prostate biopsy and compared the rates of complicated urinary tract infection and significant rectal bleeding with the rates in our previous report of complications using a then-standard, 6-core biopsy technique, without a periprostatic block.
  
  
  RESULTS
  Three patients developed complicated urinary tract infections, two of which were with ciprofloxacin-resistant organisms. This was not a significant different statistically from our earlier report. Seven patients had significant rectal bleeding requiring endoscopic intervention. This rate also was not significantly different statistically from our earlier report.
  
  
  CONCLUSIONS
  Our infection and rectal bleeding complications associated with contemporary transrectal ultrasound-guided prostate biopsy were low. We experienced a small, nonstatistically significant, increase in the complicated urinary tract infection rate and a small, nonstatistically significant, increase in the rectal bleeding rate in association with the transition from an eight-core, no periprostatic block, technique to the contemporary technique.
authors: Urological Associates of Lancaster, Limited, Lancaster, Pennsylvania 17604-3200, USA. psieber610@aol.com
authors: Paul R
authors: PR
authors: Sieber
authors: F M
authors: FM
authors: Rommel
authors: Chris G
authors: CG
authors: Theodoran
authors: Robert D
authors: RD
authors: Hong
authors: Michael A
authors: MA
authors: Del Terzo
mesh_terms: D000779:Anesthetics, Local; D001340:Autonomic Nerve Block; D001707:Biopsy, Needle / Q000009:adverse effects* / Q000295:instrumentation / Q000379:methods; D024881:Drug Resistance, Bacterial; D018479:Early Intervention, Educational; D004837:Epinephrine / Q000627:therapeutic use; D006471:Gastrointestinal Hemorrhage / Q000453:epidemiology / Q000209:etiology* / Q000517:prevention & control; D006801:Humans; D007193:Independent Practice Associations; D008012:Lidocaine; D008297:Male; D011446:Prospective Studies; D011467:Prostate / Q000473:pathology*; D012007:Rectum; D014552:Urinary Tract Infections / Q000453:epidemiology / Q000209:etiology* / Q000382:microbiology; D014572:Urology / Q000458:organization & administration
chemical_list: D000779:Anesthetics, Local; D008012:Lidocaine; D004837:Epinephrine