Resection of gliomas using positron emission tomography/computed tomography neuronavigation.
Two patients presented with provisional diagnoses of glioma. Computed tomography (CT) and magnetic resonance imaging failed to show the boundaries of the tumor clearly. Positron emission tomography (PET)/CT with [(18)F]fluorodeoxyglucose and (11)C-methionine clearly showed the location, extent, and heterogeneity of the tumors. The tumors were resected under PET/CT neuronavigation guidance. Histological examination of the specimens showed that PET/CT neuronavigation provided reliable distinction between normal brain and glioma, and that the uptake of PET tracers can indicate the degree of proliferation.
Yang
Shuyuan
S
Department of Neurosurgery, PET/CT Center, Tianjin Medical University General Hospital, PRC. dhcan@public.tpt.tj.cn
Zhang
Chuan
C
Zhu
Tao
T
Cai
Li
L
Gao
Shuo
S
Yue
Shuyuan
S
Wei
Wei
W
D000368:Aged; D001932:Brain Neoplasms / Q000000981:diagnostic imaging / Q000601:surgery*; D005910:Glioma / Q000000981:diagnostic imaging / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D038361:Neuronavigation / Q000379:methods*; D049268:Positron-Emission Tomography; D014057:Tomography, X-Ray Computed