Serious haematological toxicity of cyclophosphamide in relation to CYP2B6, GSTA1 and GSTP1 polymorphisms.
Tran
Agnès
A
Bournerias
François
F
Le Beller
Christine
C
Mir
Olivier
O
Rey
Elisabeth
E
Pons
Gérard
G
Delahousse
Michel
M
Tréluyer
Jean-Marc
JM
D000328:Adult; D001189:Aryl Hydrocarbon Hydroxylases / Q000235:genetics*; D003520:Cyclophosphamide / Q000009:adverse effects*; D065702:Cytochrome P-450 CYP2B6; D005260:Female; D051549:Glutathione S-Transferase pi / Q000235:genetics*; D005982:Glutathione Transferase / Q000235:genetics*; D006402:Hematologic Diseases / Q000139:chemically induced* / Q000175:diagnosis / Q000201:enzymology; D006801:Humans; D010089:Oxidoreductases, N-Demethylating / Q000235:genetics*; D011110:Polymorphism, Genetic / Q000235:genetics
D003520:Cyclophosphamide; D001189:Aryl Hydrocarbon Hydroxylases; C585599:CYP2B6 protein, human; D065702:Cytochrome P-450 CYP2B6; D010089:Oxidoreductases, N-Demethylating; C484555:GSTA1 protein, human; C496556:GSTP1 protein, human; D051549:Glutathione S-Transferase pi; D005982:Glutathione Transferase