title: A new anti-HIV lupane acid from Gleditsia sinensis Lam.
abstract: A new lupane acid, 2beta-carboxyl,3beta-hydroxyl-norlupA (1)-20 (29)-en-28-oic acid (1), together with five known lupane acid derivatives (2-6), were isolated from the stings of Gleditsia sinensis Lam.. Their structures were elucidated on the basis of 1D and 2D NMR techniques. All these known compounds were isolated from this genus for the first time. The new compound 1 showed strong anti-HIV activity.
authors: College of Life Science and Technology, Xi'an Jiao Tong University, China.
authors: Wan-Hua
authors: WH
authors: Li
authors: Xiang-Ming
authors: XM
authors: Zhang
authors: Rong-Ren
authors: RR
authors: Tian
authors: Yong-Tang
authors: YT
authors: Zheng
authors: Wen-Ming
authors: WM
authors: Zhao
authors: Ming-Hua
authors: MH
authors: Qiu
mesh_terms: D019380:Anti-HIV Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D002460:Cell Line; D031501:Gleditsia / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D008826:Microbial Sensitivity Tests; D013055:Spectrophotometry, Infrared; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D053978:Pentacyclic Triterpenes
chemical_list: D019380:Anti-HIV Agents; D014315:Triterpenes; C480546:lupane; D053978:Pentacyclic Triterpenes