Reticulohistiocytosis.
Reticulohistiocytoses consist of a rare group of diseases caused by CD68+ macrophage proliferation. Several advances have been achieved in relation to the receptors involved in these diseases. This knowledge will clarify the physiopathologic mechanisms of the reticulohistiocytoses and direct better therapeutic approaches for patients.
Luz
Flávio Barbosa
FB
General Policlinics of Rio de Janeiro/Carlos Chagas Medical Post-Graduation Institute, Rua Desembargador Izidro 28/1001, 20521-160 Rio de Janeiro, Brazil.
Kurizky
Patricia Shu
PS
Ramos-e-Silva
Marcia
M
D015703:Antigens, CD / Q000032:analysis; D015214:Antigens, Differentiation, Myelomonocytic / Q000032:analysis; D006644:Histiocytes / Q000378:metabolism*; D015616:Histiocytosis, Non-Langerhans-Cell / Q000188:drug therapy / Q000378:metabolism / Q000473:pathology; D006801:Humans; D007155:Immunologic Factors / Q000627:therapeutic use*; D039841:Leukocyte L1 Antigen Complex / Q000276:immunology; D011956:Receptors, Cell Surface / Q000276:immunology; D012867:Skin / Q000473:pathology; D014409:Tumor Necrosis Factor-alpha / Q000037:antagonists & inhibitors; D000097382:CD68 Molecule
D015703:Antigens, CD; D015214:Antigens, Differentiation, Myelomonocytic; D007155:Immunologic Factors; D039841:Leukocyte L1 Antigen Complex; D011956:Receptors, Cell Surface; D014409:Tumor Necrosis Factor-alpha; C067980:CD68 antigen, human; D000097382:CD68 Molecule