[Familial tumoral calcinosis in three patients in the same family].
Tumoral calcinosis is a rare condition characterized by large calcific soft tissue deposits occurring predominantly in a periarticular location. Familial tumoral calcinosis was detected in three members of a family, namely, the father and two offsprings. The father underwent many operations since age 10 for occurrences or recurrences of mass lesions in the right posterior elbow, both hips, left gluteal region, and perineal region. His 16-year-old son underwent his first operation at the age of 10 for a lesion in the posterior elbow, which recurred at the same site and required another operation two years later. He underwent subsequent surgeries for lesions that appeared in the right elbow and right dorsal foot. Finally, the 12-year-old daughter was treated with surgery for a lesion in the right dorsal foot. In all the patients, pathologic diagnoses of all surgical specimens were reported as tumoral calcinosis. All had normocalcemia, hyperphosphatemia, and D hypervitaminosis.
Yurdoğlu
Cihangir
C
Okmeydani Eğitim ve Araştirma Hastanesi Ortopedi ve Travmatoloji Kliniği. cyurdoglu@yahoo.com
Ozbaydar
Mehmet Uğur
MU
Adaş
Müjdat
M
Ozger
Harzem
H
D000293:Adolescent; D000328:Adult; D001859:Bone Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000235:genetics / Q000473:pathology / Q000601:surgery; D002114:Calcinosis / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000235:genetics / Q000473:pathology / Q000601:surgery; D002648:Child; D003937:Diagnosis, Differential; D004550:Elbow / Q000473:pathology; D005260:Female; D005528:Foot / Q000473:pathology; D020022:Genetic Predisposition to Disease; D006615:Hip / Q000473:pathology; D006801:Humans; D008297:Male; D010375:Pedigree; D011859:Radiography