MR imaging evaluation of regional, remote, and global effects of percutaneous transluminal septal myocardial ablation in hypertrophic obstructive cardiomyopathy.
OBJECTIVE
To evaluate regional, remote, and global effects of percutaneous transluminal septal myocardial ablation (PTSMA) in hypertrophic obstructive cardiomyopathy (HOCM) using magnetic resonance (MR) imaging.


METHODS
Twenty-one patients with HOCM underwent cine and delayed contrast-enhanced MR imaging. The regional effects of ablated myocardium as well as remote and global effects of PTSMA were assessed.


RESULTS
The ablated interventricular septal myocardium was hyperenhanced and thinned after successful PTSMA. Decreases in posterior wall thickness and myocardial mass were observed more than 12 weeks after PTSMA. Decreases in posterior wall thickness, myocardial mass, and left atrial diameter were observed in patients without myocardial hyperenhancement before PTSMA. Neither reduction nor increase in hyperenhancing myocardium, except for the ablated myocardium, was observed after PTSMA.


CONCLUSIONS
Cardiac MR imaging showed regional, remote, and global effects of PTSMA on the myocardium in HOCM and might indicate patients with a good global response to PTSMA.
Amano
Yasuo
Y
Department of Radiology, Nippon Medical School, Tokyo, Japan. yas-amano@nifty.com
Takayama
Morimasa
M
Kumita
Shinichiro
S
Kumazaki
Tatsuo
T
D000328:Adult; D000368:Aged; D015906:Angioplasty, Balloon, Coronary; D002312:Cardiomyopathy, Hypertrophic / Q000601:surgery*; D017115:Catheter Ablation; D005260:Female; D006801:Humans; D007089:Image Enhancement; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D008875:Middle Aged; D009040:Motion Pictures