A doubly resonant cavity for detection of RF demodulation by living cells.
We describe the design, construction, and operating characteristics of a doubly resonant cylindrical microwave cavity. This cavity has been developed to allow a search for nonlinear RF energy conversion in biological cells. Cells with a diode-like nonlinearity could demodulate a modulated RF carrier wave and generate low frequency signals in an exposed biological preparation. The cavity is designed to be resonant on the TE(111) mode at about 890 MHz and on the TE(113) mode at about 1780 MHz. The cavity performs exactly as designed and has proved capable of detecting the nonlinearity in a microscopic Schottky diode test structure. The sensitivity is sufficient to detect any nonlinearity in a collection of biological cells that could have any potential biological significance.
Balzano
Quirino
Q
Department of Electrical and Computer Engineering, University of Maryland, College Park, Maryland 20742, USA. qbalzano@umd.edu
Hodzic
Vildana
V
Gammon
Robert W
RW
Davis
Christopher C
CC
D018929:Cell Culture Techniques / Q000295:instrumentation*; D002468:Cell Physiological Phenomena / Q000528:radiation effects*; D017076:Computer-Aided Design; D055590:Electromagnetic Phenomena / Q000295:instrumentation*; D004867:Equipment Design; D019544:Equipment Failure Analysis; D008872:Microwaves; D011829:Radiation Dosage; D011846:Radio Waves; D011874:Radiometry / Q000295:instrumentation* / Q000379:methods