Gallium phosphide nanowires as a substrate for cultured neurons.
Dissociated sensory neurons were cultured on epitaxial gallium phosphide (GaP) nanowires grown vertically from a gallium phosphide surface. Substrates covered by 2.5 microm long, 50 nm wide nanowires supported cell adhesion and axonal outgrowth. Cell survival was better on nanowire substrates than on planar control substrates. The cells interacted closely with the nanostructures, and cells penetrated by hundreds of wires were observed as well as wire bending due to forces exerted by the cells.
Hällström
Waldemar
W
Division of Solid State Physics and The Nanometer Structure Consortium, Lund University, P.O Box 118, 221 00 Lund, Sweden. waldemar.hallstrom@ftf.lth.se
Mårtensson
Thomas
T
Prinz
Christelle
C
Gustavsson
Per
P
Montelius
Lars
L
Samuelson
Lars
L
Kanje
Martin
M
D000818:Animals; D002448:Cell Adhesion / Q000502:physiology; D018929:Cell Culture Techniques / Q000379:methods*; D002478:Cells, Cultured; D003460:Crystallization / Q000379:methods*; D005708:Gallium / Q000737:chemistry*; D046911:Macromolecular Substances / Q000737:chemistry; D008422:Materials Testing; D051379:Mice; D008968:Molecular Conformation; D036103:Nanotechnology / Q000379:methods; D043942:Nanotubes / Q000737:chemistry* / Q000648:ultrastructure*; D009474:Neurons / Q000166:cytology* / Q000502:physiology; D010316:Particle Size; D010720:Phosphines / Q000737:chemistry*; D013499:Surface Properties; D023822:Tissue Engineering / Q000379:methods*
D046911:Macromolecular Substances; D010720:Phosphines; C485338:gallium phosphide; D005708:Gallium