title: Thermal deterioration of oil and frying foodstuffs.
abstract: Male Wistar rats were fed ad libitum for 12 weeks a powdered diet (AIN93G; no fat) containing 7 wt% of fresh oil (control), and frying oils heated for 20 h at 180 degrees C with amino acids, gluten, sugar, and wheat starch, respectively. The rats were subjected to anthropometric measurements, hematological analyses, and observations of the liver and kidneys. All of the rats grew well, and no gross symptoms attributable to the experimental oils were observed. The serum of all the experimental groups showed a tendency toward lower levels of triacylglycerol and free fatty acids and higher levels of aspartate aminotransferase (AST) and alanine aminotransferase (ALT) than that of the control group. Among experimental groups, the rats fed a diet containing oil heated with gluten were least influenced by thermally deteriorated oil in terms of serum levels of glucose, triacylglycerol, phospholipids, cholesterol, and insulin; histological evaluations; and number of dark-red patches found on the surface of the liver.
authors: Faculty of Nutrition, Kobe-Gakuin University, Kobe, Japan. totani@nutr.kobegakuin.ac.jp
authors: Nagao
authors: N
authors: Totani
authors: Yuko
authors: Y
authors: Ojiri
mesh_terms: D000410:Alanine Transaminase / Q000097:blood; D000818:Animals; D001219:Aspartate Aminotransferases / Q000097:blood; D001774:Blood Chemical Analysis; D056486:Chemical and Drug Induced Liver Injury; D003296:Cooking; D004036:Diet, Atherogenic; D004041:Dietary Fats / Q000032:analysis*; D005230:Fatty Acids, Nonesterified / Q000097:blood; D005502:Food; D048788:Growth and Development / Q000187:drug effects; D006358:Hot Temperature / Q000009:adverse effects*; D007674:Kidney Diseases / Q000097:blood / Q000139:chemically induced; D008107:Liver Diseases / Q000097:blood; D008297:Male; D009821:Oils / Q000737:chemistry* / Q000633:toxicity*; D051381:Rats; D017208:Rats, Wistar
chemical_list: D004041:Dietary Fats; D005230:Fatty Acids, Nonesterified; D009821:Oils; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase