title: Peroral cholangioscopic diagnosis of biliary-tract diseases by using narrow-band imaging (with videos).
abstract: BACKGROUND
  Narrow-band imaging (NBI) makes it possible to emphasize the imaging of certain features, such as mucosal structures and mucosal microvessels in GI-tract diseases. Recently, video peroral cholangioscopy (POCS) was developed as a diagnostic modality for better visualization of bile-duct lesions; however, there is no report on POCS by using NBI.
  
  
  OBJECTIVE
  To evaluate the clinical usefulness of POCS by using NBI for the diagnosis of biliary-tract diseases.
  
  
  METHODS
  Prospective case study.
  
  
  METHODS
  This procedure was performed at Tokyo Medical University Hospital.
  
  
  METHODS
  Twelve consecutive patients with biliary-tract diseases, including 7 bile-duct cancers and 5 benign biliary diseases, which revealed 6 bile-duct strictures and 6 filling defects by ERCP.
  
  
  METHODS
  All patients underwent POCS by using NBI.
  
  
  METHODS
  Efficacy and safety of this technique.
  
  
  RESULTS
  Twenty-one lesions were evaluated by using POCS with conventional white light imaging and NBI. Although visualization of only 2 lesions (9.5%) was "excellent" by conventional observation, visualization of 12 lesions (57.4%) was "excellent" by NBI observation. Identification of the surface structure and vessels of the lesions by NBI observation was significantly better than with conventional observation (P < .01 and P < .05, respectively).
  
  
  CONCLUSIONS
  Maneuverability and fragility of POCS. The current POCS is not equipped with magnification.
  
  
  CONCLUSIONS
  POCS by using NBI may be helpful for the observation of both fine mucosal structures and tumor vessels.
authors: Department of Gastroenterology and Hepatology, Tokyo Medical University, Tokyo, Japan.
authors: Takao
authors: T
authors: Itoi
authors: Atsushi
authors: A
authors: Sofuni
authors: Fumihide
authors: F
authors: Itokawa
authors: Takayoshi
authors: T
authors: Tsuchiya
authors: Toshio
authors: T
authors: Kurihara
authors: Kentaro
authors: K
authors: Ishii
authors: Shujiro
authors: S
authors: Tsuji
authors: Fuminori
authors: F
authors: Moriyasu
authors: Takuji
authors: T
authors: Gotoda
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001660:Biliary Tract Diseases / Q000175:diagnosis*; D003937:Diagnosis, Differential; D020776:Endoscopes, Gastrointestinal; D016099:Endoscopy, Gastrointestinal / Q000379:methods*; D004867:Equipment Design; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D015203:Reproducibility of Results; D014741:Video Recording / Q000379:methods*