[Effects of electroacupuncture of Sanyinjiao (SP 6) on genito-endocrine in patients with perimenopausal syndrome].
OBJECTIVE
To observe the regulative effect of electroacupuncture (EA) of Sanyinjiao (SP 6) on genito-endocrine in patients with perimenopausal syndrome (PMS).


METHODS
A total of 175 PMS patients (157 cases with complete data) were randomized into EA group (n=81) and medication group (n=76) according to multi-center (3 hospitals) and single-blind control trial method. EA (2/100 Hz, 8-10 mA) was applied to bilateral Sanyinjiao (SP 6) for 30 min, 3 times every week, with one month being a therapeutic course, 3 courses altogether. Patients in medication group were ordered to take nilestriol (2 mg, twice/month for 3 months) and medrysone (2 mg, t. i. d. for 10 days from the 3rd month on). Serum estradiol (E) 2, follicle-stimulating hormone (FSH) and luteinizing hormone (LH) were detected with a chemiluminescence immo-analysis system.


RESULTS
After EA treatment, serum FSH and LH contents decreased significantly and serum E2 increased considerably (P < 0.001) compared with its basic values. Comparison between two groups showed that FSH, LH and E2 levels in EA group were significantly lower than those of medication group (P < 0.05).


CONCLUSIONS
EA of Sanyinjiao (SP 6) has a good regulative effect on reproductive endocrine function in PMS patients.
Qin
Zheng-yu
ZY
Clinical School of Acu-moxibustion, Osteology and Traumatology, Anhui College of Chinese Medicine, Hefei 230038, China.
Ling
Hu
H
Xia
Xiao-hong
XH
Meng
Li
L
Wu
Zi-jian
ZJ
D015669:Acupuncture Points; D015671:Electroacupuncture; D004958:Estradiol / Q000097:blood; D005260:Female; D005640:Follicle Stimulating Hormone / Q000097:blood; D006801:Humans; D007986:Luteinizing Hormone / Q000097:blood; D008593:Menopause; D008875:Middle Aged; D016037:Single-Blind Method
D004958:Estradiol; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone