title: Spectroscopic (FT-IR, FT-Raman, UV) and microbiological studies of di-substituted benzoates of alkali metals.
abstract: The FT-IR, FT-Raman and UV spectra of 3,5-dihydroxybenzoic and 3,5-dichlorobenzoic acids as well as lithium, sodium, potassium, rubidium, caesium 3,5-dihydroxy- and 3,5-dichlorobenzoates were recorded, assigned and compared. The theoretical geometries, Mulliken atomic charges, IR wavenumbers were obtained in B3LYP/6-311++G** level. On the basis of the gathered experimental and theoretical data the effect of metals and substituents on the electronic system of studied compounds were investigated. Moreover, the antimicrobiological activity of studied compounds against two species of bacteria: Bacillus subtilis, Staphylococus aureus and one species of yeast: Candida albicans were studied after 24 and 48 h of incubation. The attempt was made, to find out whether there is any correlation between the first principal component and the degree of growth inhibition exhibited by studied compounds in relation to selected microorganisms.
authors: Department of Chemistry, Białystok Technical University, Zamenhofa 29, 15-435 Białystok, Poland.
authors: M
authors: M
authors: Kalinowska
authors: R
authors: R
authors: Swisłocka
authors: M
authors: M
authors: Borawska
authors: J
authors: J
authors: Piekut
authors: W
authors: W
authors: Lewandowski
mesh_terms: D001412:Bacillus subtilis / Q000187:drug effects; D002176:Candida albicans / Q000187:drug effects; D002723:Chlorobenzoates / Q000032:analysis* / Q000737:chemistry / Q000494:pharmacology*; D008672:Metals, Alkali / Q000032:analysis* / Q000737:chemistry / Q000494:pharmacology*; D008956:Models, Chemical; D015394:Molecular Structure; D013053:Spectrophotometry / Q000379:methods*; D013056:Spectrophotometry, Ultraviolet; D017550:Spectroscopy, Fourier Transform Infrared; D013059:Spectrum Analysis, Raman; D013211:Staphylococcus aureus / Q000187:drug effects; D013997:Time Factors
chemical_list: D002723:Chlorobenzoates; D008672:Metals, Alkali