Travel-acquired scrub typhus: emphasis on the differential diagnosis, treatment, and prevention strategies.
Scrub typhus should be considered in any febrile patient presenting with a macular rash, a polyadenopathy, an eschar, or a history of environmental exposure in endemic areas. The differential diagnosis includes malaria, typhoid fever, leptospirosis, and arboviroses. Doxycycline 100 mg twice daily for 7 days should be initiated as soon as the disease is suspected.
Nachega
Jean B
JB
Department of International Health, Johns Hopkins University, Bloomberg School of Public Health, Baltimore, MD 21205, USA, and Department of Internal Medicine, St-Luc University Hospital, Brussels, Belgium. jnachega@jhsph.edu
Bottieau
Emmanuel
E
Zech
Francis
F
Van Gompel
Alfons
A
D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D001530:Belgium; D003937:Diagnosis, Differential; D004318:Doxycycline / Q000008:administration & dosage; D005076:Exanthema / Q000209:etiology; D005335:Fever of Unknown Origin / Q000209:etiology; D006801:Humans; D007194:India; D007922:Leptospirosis / Q000175:diagnosis; D008288:Malaria / Q000175:diagnosis; D008297:Male; D008875:Middle Aged; D018570:Risk Assessment; D012612:Scrub Typhus / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy*; D014195:Travel; D014330:Tropical Medicine / Q000379:methods; D014435:Typhoid Fever / Q000175:diagnosis
D000900:Anti-Bacterial Agents; D004318:Doxycycline