title: Potassium additive algorithm for use in continuous renal replacement therapy.
abstract: The performance of continuous renal replacement therapy (CRRT) brings about alterations in the serum potassium levels in patient. Potassium is an electrolyte essential for the regulation of nerve conduction and muscle contraction, particularly important in the case of cardiac muscle. This article describes the physiological mechanisms that affect potassium distribution throughout the body and also describes the effects of hypokalaemia or hyperkalaemia on the heart. This article justifies the need for serum potassium control during CRRT, which recognizes and reconciles the differing areas of responsibility of the medical and nursing staff. This article critically reviews the steps taken to develop and implement into clinical practice and evaluate a potassium additive algorithm. It also discusses the implications of this initiative.
authors: Intensive Care Unit, Southmead Hospital, Bristol, UK.
authors: Gail
authors: G
authors: Brooks
mesh_terms: D000465:Algorithms; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D005260:Female; D006440:Hemofiltration / Q000009:adverse effects / Q000379:methods; D006801:Humans; D007008:Hypokalemia / Q000188:drug therapy* / Q000209:etiology; D007676:Kidney Failure, Chronic / Q000175:diagnosis / Q000628:therapy*; D008297:Male; D010531:Peritoneal Dialysis, Continuous Ambulatory / Q000009:adverse effects / Q000379:methods; D011188:Potassium / Q000008:administration & dosage*; D011379:Prognosis; D017582:Renal Replacement Therapy / Q000009:adverse effects* / Q000451:nursing; D018570:Risk Assessment; D016896:Treatment Outcome; D006113:United Kingdom; D014883:Water-Electrolyte Imbalance / Q000517:prevention & control
chemical_list: D011188:Potassium