Oral hydration during growth hormone stimulation with clonidine.
The arginine-clonidine growth hormone (GH) stimulation test causes hypotension, requiring intravenous fluids to stabilize blood pressure (BP) and delaying departure from clinic. We hypothesized that oral hydration during the stimulation test would decrease need for intravenous fluids and shorten clinic stay. Children drank a diet electrolyte drink (10 ml/kg) on arrival to the test, which was repeated after clonidine. Fifteen children (7 girls) were tested without oral hydration, and 23 (6 girls) were tested with oral hydration (age range, 2-15 years). Compared with no oral hydration, intake of >13 ml/kg rarely required intravenous fluids, improved diastolic BP, and permitted discharge at the end of the GH test, with a higher BP.
May
Melissa
M
Division of Nursing, Cincinnati Children's Hospital Medical Center, University of Cincinnati, Cincinnati, OH, USA.
Rose
Susan R
SR
D000293:Adolescent; D001120:Arginine / Q000009:adverse effects; D002253:Carbonated Beverages; D002648:Child; D002675:Child, Preschool; D015400:Clinical Nursing Research; D003000:Clonidine / Q000009:adverse effects; D005260:Female; D005440:Fluid Therapy / Q000379:methods* / Q000451:nursing; D006130:Growth Disorders / Q000097:blood / Q000175:diagnosis* / Q000209:etiology; D019382:Human Growth Hormone / Q000097:blood / Q000172:deficiency / Q000187:drug effects; D006801:Humans; D007022:Hypotension / Q000139:chemically induced / Q000175:diagnosis / Q000517:prevention & control; D007902:Length of Stay; D008297:Male; D009730:Nursing Assessment; D010371:Pediatric Nursing; D010901:Pituitary Function Tests / Q000009:adverse effects* / Q000379:methods / Q000451:nursing; D015532:Rehydration Solutions / Q000627:therapeutic use; D012894:Sleep Stages / Q000187:drug effects; D016896:Treatment Outcome
D015532:Rehydration Solutions; D019382:Human Growth Hormone; D001120:Arginine; D003000:Clonidine