Palladium-catalyzed oxidative amination of alkenes: improved catalyst reoxidation enables the use of alkene as the limiting reagent.
Palladium-catalyzed methods for intermolecular aerobic oxidative amination of alkenes have been identified that are compatible with the use of alkene as the limiting reagent. These procedures, which enhance the utility of this reaction with alkenes that are not commercially available, are demonstrated with substrates bearing dialkyl ether, carboxyester, epoxide, and silyl ether groups.
Rogers
Michelle M
MM
Department of Chemistry, University of Wisconsin-Madison, 1101 University Avenue, Madison, Wisconsin 53706, USA.
Kotov
Vasily
V
Chatwichien
Jaruwan
J
Stahl
Shannon S
SS
D000475:Alkenes / Q000138:chemical synthesis / Q000737:chemistry*; D000586:Amination; D002384:Catalysis; D020650:Combinatorial Chemistry Techniques; D007202:Indicators and Reagents; D010084:Oxidation-Reduction; D010165:Palladium / Q000737:chemistry*
D000475:Alkenes; D007202:Indicators and Reagents; D010165:Palladium