title: Increased activation of nuclear factor-kappa B (NF-kappaB) in isolated peritoneal macrophages of patients with endometriosis.
abstract: Endometriosis is characterized by pelvic inflammation that shows an increased number of activated peritoneal macrophages and their secreted products such as cytokines, growth factors, and angiogenic factors. Our results show that activation of nuclear factor-kappa B (NF-kappaB), a pro-inflammatory transcription factor, is statistically significantly increased in peritoneal macrophages from patients with endometriosis when compared with controls.
authors: Fonds de la Recherche Scientifique, FNRS, Belgium.
authors: Jean-Christophe
authors: JC
authors: Lousse
authors: Anne
authors: A
authors: Van Langendonckt
authors: Reinaldo
authors: R
authors: González-Ramos
authors: Sylvie
authors: S
authors: Defrère
authors: Emmanuelle
authors: E
authors: Renkin
authors: Jacques
authors: J
authors: Donnez
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D002467:Cell Nucleus / Q000737:chemistry; D004715:Endometriosis / Q000378:metabolism*; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008262:Macrophage Activation; D017737:Macrophages, Peritoneal / Q000737:chemistry*; D012720:Severity of Illness Index; D051996:Transcription Factor RelA / Q000032:analysis*
chemical_list: D051996:Transcription Factor RelA