Paracoccidioidomycosis: no genetic damage in human peripheral blood cells of patients assessed by single-cell gel (comet) assay.
Paracoccidioidomycosis is a systemic fungal infection caused by Paracoccidioides brasiliensis. As infectious diseases can cause DNA damage, the authors aimed at analyzing DNA breakage in peripheral blood cells of patients with paracoccidioidomycosis by using the comet assay. The results suggested that paracoccidioidomycosis does not cause genotoxicity.
Ribeiro-Vieira
Renata Aparecida Martinez Antunes
RA
Department of Dermatology and Radiotherapy, Botucatu School of Medicine, São Paulo State University, Botucatu, SP.
Ribeiro
Daniel Araki
DA
Salvadori
Daisy Maria Favero
DM
Marques
Sílvio Alencar
SA
D000328:Adult; D020552:Comet Assay; D004249:DNA Damage; D006801:Humans; D007963:Leukocytes, Mononuclear / Q000737:chemistry*; D010229:Paracoccidioidomycosis / Q000235:genetics* / Q000378:metabolism