Primary bladder neck obstruction in men, women, and children.
The understanding of the presentation, diagnosis, and treatment of primary bladder neck obstruction (PBNO) has evolved over the last 20 years. It was first identified 70 years ago, but the etiology is still unclear. There are multiple theories as to the etiology, including muscular and neurological dysfunction and fibrosis. Over the years, many voiding parameters and cut points and nomograms have been presented for diagnosis of nonneurogenic functional bladder outlet obstruction in young men. Until recently, there was a paucity of data on PBNO in women and children. Videourodynamics provide an accurate diagnosis of PBNO but for some patients are an invasive option. Treatments vary from watchful waiting to alpha-blockade to surgery, depending on the severity of symptoms, urodynamic findings, and response to medical therapy. This paper reviews the theories on etiology, incidence, presentation, and diagnostic evaluation, and briefly discusses treatment options for PBNO.
Padmanabhan
Priya
P
Nitti
Victor W
VW
D000293:Adolescent; D000317:Adrenergic alpha-Antagonists / Q000627:therapeutic use*; D000328:Adult; D017677:Age Distribution; D002648:Child; D003131:Combined Modality Therapy; D003558:Cystoscopy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D011379:Prognosis; D018570:Risk Assessment; D012720:Severity of Illness Index; D017678:Sex Distribution; D001748:Urinary Bladder Neck Obstruction / Q000175:diagnosis* / Q000453:epidemiology* / Q000628:therapy; D014555:Urination Disorders / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy; D014563:Urodynamics; D013520:Urologic Surgical Procedures / Q000379:methods*
D000317:Adrenergic alpha-Antagonists