title: Follow-up analysis on the epidemic strains of Orientia tsutsugamushi in the first outbreak of scrub typhus in Henan Province, China.
abstract: To obtain knowledge of the genetic characteristics and types of the epidemic strains of Orientia tsutsugamushi in the first outbreak of scrub typhus in Henan Province, genus and type-specific primers were employed to amplify a fragment of the gene of 56 kDa protein. Serotyping demonstrated that, of the 19 patients [15 patients in recovery phase (10-40 days) and 4 of patients in acute phase (1-7 days)], 4 were infected with Gilliam type, 8 with Kato type, 6 with Karp type, and 1 with an unknown type. Successful genotyping was obtained for only 3 patients, indicating that 2 were infected with Karp type and 1 with Taiwan Kato type. Thus the outbreak of scrub typhus in Henan Province was caused by at least two epidemic strains.
authors: Department of Rickettsiology, National Institute of Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China. zhanglijuan@icdc.cn
authors: Lijuan
authors: L
authors: Zhang
authors: Zhang
authors: Z
authors: Jin
authors: Shengli
authors: S
authors: Xia
authors: Jingshan
authors: J
authors: Zhang
authors: Menglei
authors: M
authors: Li
authors: Xiuping
authors: X
authors: Fu
authors: Mingchun
authors: M
authors: Luan
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D002681:China / Q000453:epidemiology; D004196:Disease Outbreaks; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D012285:Orientia tsutsugamushi / Q000472:pathogenicity*; D011159:Population Surveillance; D012612:Scrub Typhus / Q000175:diagnosis / Q000453:epidemiology* / Q000469:parasitology / Q000503:physiopathology