title: Dipole-LUMO/dipolarophile-HOMO controlled asymmetric cycloadditions of carbonyl ylides catalyzed by chiral Lewis acids.
abstract: We have found the first successful example of reverse-electron-demand dipole-LUMO/dipolarophile-HOMO controlled cycloaddition reactions between carbonyl ylides, which were generated from o-methoxycarbonyl-alpha-diazoacetophenone and their acyl derivatives as precursors, and vinyl ether derivatives with high levels of asymmetric induction (97-77% ee) using chiral 2,6-(oxazolinyl)pyridine-Eu(III) or binaphthyldiimine-Ni(II) complexes as chiral Lewis acid catalysts.
authors: Department of Chemistry and Material Engineering, Faculty of Engineering, Shinshu University, Wakasato, Nagano 380-8553, Japan. sugahio@shinshu-u.ac.jp
authors: Hiroyuki
authors: H
authors: Suga
authors: Daisuke
authors: D
authors: Ishimoto
authors: Satoshi
authors: S
authors: Higuchi
authors: Motoo
authors: M
authors: Ohtsuka
authors: Tadashi
authors: T
authors: Arikawa
authors: Teruko
authors: T
authors: Tsuchida
authors: Akikazu
authors: A
authors: Kakehi
authors: Toshihide
authors: T
authors: Baba