Temporal pole signal abnormality on MR imaging in temporal lobe epilepsy with hippocampal sclerosis: a fluid-attenuated inversion-recovery study.
OBJECTIVE
To determine the frequency and regional involvement of temporal pole signal abnormality (TPA) in patients with hippocampal sclerosis (HS) using fluid-attenuated inversion-recovery (FLAIR) MR imaging, and to correlate this feature with history.


METHODS
Coronal FLAIR images of the temporal pole were assessed in 120 patients with HS and in 30 normal subjects, to evaluate gray-white matter demarcation.


RESULTS
Ninety (75%) of 120 patients had associated TPA. The HS side made difference regarding the presence of TPA, with a left side prevalence (p=0.04, chi2 test). The anteromedial zone of temporal pole was affected in 27 (30%) out of 90 patients. In 63 (70%) patients the lateral zone were also affected. Patients with TPA were younger at seizure onset (p=0.018), but without association with duration of epilepsy.


CONCLUSIONS
Our FLAIR study show temporal pole signal abnormality in 3/4 of patients with HS, mainly seen on the anteromedial region, with a larger prevalence when the left hippocampus was involved.
Carrete
Henrique
H
Departamento de Diagnóstico por Imagem, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, SP, Brazil.
Abdala
Nitamar
N
Lin
Kátia
K
Caboclo
Luís Otávio
LO
Centeno
Ricardo Silva
RS
Sakamoto
Américo Ceiki
AC
Szjenfeld
Jacob
J
Nogueira
Roberto Gomes
RG
Yacubian
Elza Márcia Targas
EM
D000293:Adolescent; D000328:Adult; D017668:Age of Onset; D001927:Brain Diseases / Q000453:epidemiology / Q000473:pathology*; D001938:Brazil / Q000453:epidemiology; D016009:Chi-Square Distribution; D004833:Epilepsy, Temporal Lobe / Q000453:epidemiology / Q000473:pathology*; D005260:Female; D007839:Functional Laterality; D006624:Hippocampus / Q000473:pathology*; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D008875:Middle Aged; D012598:Sclerosis; D012815:Signal Processing, Computer-Assisted; D013702:Temporal Lobe / Q000002:abnormalities* / Q000473:pathology*; D013997:Time Factors