Prophylaxis of infective endocarditis: prevention of the perfect storm.
Despite the availability of endocarditis prophylaxis guidelines for more than five decades, no prospective, randomised trial has ever been conducted to evaluate the efficacy and safety of this practice. This fact, in combination with mixed results from case-control investigations and other factors, has prompted a re-evaluation of the appropriateness of the guidelines. The update provided herein highlights recent revisions in guidelines promulgated by different countries.
Baddour
Larry M
LM
Mayo Clinic College of Medicine, USA. Baddour.Larry@mayo.edu
D019072:Antibiotic Prophylaxis; D004696:Endocarditis / Q000517:prevention & control*; D006801:Humans; D017410:Practice Guidelines as Topic