Recent developments in the understanding of nuclear protein import.
The process of nucleocytoplasmic exchange of various macromolecules and metabolites between the nuclear and cytoplasmic compartment is crucial for cell function and survival. It is also closely involved with several pathogeneses including cancer and viral infections. Here, we will discuss the current understanding of the classical nuclear import pathway and the factors that are essential for this process.
Liu
S M
SM
Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford, UK. sai.liu@path.ox.ac.uk
Liu
W M
WM
D007700:Kinetics; D008958:Models, Molecular; D009687:Nuclear Proteins / Q000378:metabolism*; D021381:Protein Transport; D015398:Signal Transduction; D013816:Thermodynamics
D009687:Nuclear Proteins