title: Poorly differentiated adenocarcinoma with signet-ring cell carcinoma in a hyperplastic polyp of the stomach: report of a case.
abstract: Hyperplastic polyps (HPs) of the stomach have been reported to be mostly benign. However, in rare cases, carcinomas have been found in HPs. We treated a 59-year-old Japanese male who underwent a total gastrectomy, and a gross examination of the resected stomach revealed a 4.8 x 3.8-cm polyp on the greater curvature of the antrum and multiple small polyps in the whole gastric mucosa. Histologically, the large polyp consisted mainly of hyperplastic foveolar epithelium, while the presence of variously colored lobules demonstrated a poorly differentiated adenocarcinoma mixed with signet-ring cell carcinoma. Hyperplastic polyps should therefore be carefully examined microscopically as a polypectomy specimen and in resected stomach specimens.
authors: Department of Pathology, Nippon Steel Hirohata Hospital, 3-1 Yumesaki-cho, Hirohata-ku, Himeji, Hyogo 671-1122, Japan.
authors: Hiroshi
authors: H
authors: Hirano
authors: Toshimi
authors: T
authors: Yoshida
authors: Hitoshi
authors: H
authors: Yoshimura
authors: Masato
authors: M
authors: Fukuoka
authors: Eriko
authors: E
authors: Ohkubo
authors: Shiro
authors: S
authors: Tachibana
authors: Hiroshi
authors: H
authors: Saito
authors: Keiji
authors: K
authors: Nakasho
authors: Takashi
authors: T
authors: Nishigami
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis* / Q000503:physiopathology / Q000601:surgery; D018279:Carcinoma, Signet Ring Cell / Q000473:pathology / Q000601:surgery; D005743:Gastrectomy; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008875:Middle Aged; D013274:Stomach Neoplasms / Q000175:diagnosis* / Q000503:physiopathology / Q000601:surgery