title: A nine-day accelerated radiation protocol for feline squamous cell carcinoma.
abstract: Nine cats with oral squamous cell carcinoma were treated with an accelerated radiation protocol (14 fractions of 3.5 Gy in 9 days). Radiation was administered twice daily with a 6hour break between treatments. Median overall survival was 86 +/- 110 days. Median survival for cats with a partial response (n=6) was 60 +/- 7 days, while median survival for cats with a complete response (n=3) was 298 +/- 187 days (P = 0.0639). The accelerated protocol was well tolerated and toxicity in the early and late period was manageable in all cats. Further modification of the protocol is warranted to extend survival.
authors: Department of Veterinary Clinical Sciences, Washington State University, Pullman, WA 99164-6610, USA. jfidel@vetmed.wsu.edu
authors: Janean L
authors: JL
authors: Fidel
authors: Rance K
authors: RK
authors: Sellon
authors: Robert K
authors: RK
authors: Houston
authors: Betsy A
authors: BA
authors: Wheeler
mesh_terms: D000818:Animals; D002294:Carcinoma, Squamous Cell / Q000532:radiotherapy / Q000662:veterinary*; D002371:Cat Diseases / Q000401:mortality / Q000473:pathology / Q000532:radiotherapy*; D002415:Cats; D005260:Female; D008297:Male; D009062:Mouth Neoplasms / Q000532:radiotherapy / Q000662:veterinary*; D011829:Radiation Dosage; D011878:Radiotherapy / Q000662:veterinary; D016019:Survival Analysis; D016896:Treatment Outcome