title: The alternative complex III from Rhodothermus marinus - a prototype of a new family of quinol:electron acceptor oxidoreductases.
abstract: The biochemical and genetic search for a bc(1) complex in Rhodothermus marinus was always fruitless; however, a functional equivalent, i.e. having quinol:cytochrome c oxidoreductase activity was characterized. Now, with the sequencing of R. marinus genome, it was possible to assign the N-terminal sequences of several proteins of this complex to its coding genes. The alternative complex III from R. marinus has the same genomic organization of the so-called MFIcc complexes, proposed to be oxidoreductases of the respiratory and photosynthetic electron transfer chains. In this report, we establish undoubtedly the existence of an alternative complex III, a functional substitute of the bc(1) complex, by its identification at both the biochemical and genomic level.
authors: Instituto de Tecnologia Química e Biológica, Universidade Nova de Lisboa, Av. da República (EAN), APT 127, 2780-901 Oeiras, Portugal. mpereira@itqb.unl.pt
authors: Manuela M
authors: MM
authors: Pereira
authors: Patricia N
authors: PN
authors: Refojo
authors: Gudmundur O
authors: GO
authors: Hreggvidsson
authors: Sigridur
authors: S
authors: Hjorleifsdottir
authors: Miguel
authors: M
authors: Teixeira
mesh_terms: D000595:Amino Acid Sequence; D001426:Bacterial Proteins / Q000737:chemistry* / Q000235:genetics; D014450:Electron Transport Complex III / Q000737:chemistry* / Q000145:classification / Q000235:genetics; D008969:Molecular Sequence Data; D005810:Multigene Family; D021122:Protein Subunits / Q000737:chemistry / Q000235:genetics; D045245:Rhodothermus / Q000201:enzymology*
chemical_list: D001426:Bacterial Proteins; D021122:Protein Subunits; D014450:Electron Transport Complex III