title: [Two cases of stage IV gastric cancer responding to chemotherapy with S-1 or UFT].
abstract: We report patients with advanced Stage IV gastric cancer responding to chemotherapy with S-1 or UFT. Case 1: The patient was a 59-year-old man with Stage IV gastric cancer because of CY 1. After surgery, chemotherapy with S-1 (100 mg/body/day) was performed for one year and 11 months. At present, 5 years and 5 months after surgery, this patient shows no signs of tumor recurrence. Case 2: The patient was a 68-year-old woman with Stage IV gastric cancer because of P 1. She was treated with 200 mg/day of UFT for one year and 9 months. At present, 5 years after surgery, she shows no signs of tumor recurrence. We considered that the longterm survival of such patients is attributable to chemotherapy with S-1 or UFT. The OPRT activity of the two cases was high, so chemotherapy with S-1 or UFT was thought to be effective for them.
authors: Department of Surgery, Osaka Kosei-Nenkin Hospital.
authors: Yukio
authors: Y
authors: Nakamura
authors: Takeyoshi
authors: T
authors: Yumiba
authors: Yoshio
authors: Y
authors: Yamasaki
authors: Takuya
authors: T
authors: Momiyama
authors: Akira
authors: A
authors: Ito
authors: Yusuke
authors: Y
authors: Akamaru
authors: Youko
authors: Y
authors: Sugimoto
authors: Noriko
authors: N
authors: Tamaoka
authors: Naohito
authors: N
authors: Beppu
authors: Yusuke
authors: Y
authors: Watanabe
authors: Kiyoshi
authors: K
authors: Ohno
authors: Tsutomu
authors: T
authors: Kasugai
mesh_terms: D000230:Adenocarcinoma / Q000188:drug therapy*; D002288:Adenocarcinoma, Mucinous / Q000188:drug therapy*; D000368:Aged; D000964:Antimetabolites, Antineoplastic / Q000627:therapeutic use*; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D004338:Drug Combinations; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010094:Oxonic Acid / Q000627:therapeutic use*; D013274:Stomach Neoplasms / Q000188:drug therapy*; D005641:Tegafur / Q000627:therapeutic use*; D014498:Uracil / Q000627:therapeutic use
chemical_list: D000964:Antimetabolites, Antineoplastic; D004338:Drug Combinations; C079198:S 1 (combination); D005641:Tegafur; D014498:Uracil; D010094:Oxonic Acid