title: Enantioselective synthesis of the tetrahydrofuran lignans (-)- and (+)-magnolone.
abstract: The optically pure trisubstituted 7'-oxotetrahydrofuran lignans (-)- and (+)-magnolone ( 1) were synthesized by employing stereoselective S N1 intramolecular cyclization as a key reaction. The absolute configuration of naturally occurring (-)-magnolone was determined as (7 S,8 R,8' S).
authors: Faculty of Agriculture, Ehime University, 3-5-7 Tarumi, Matsuyama, Ehime 790-8566, Japan.
authors: Tomofumi
authors: T
authors: Nakato
authors: Satoshi
authors: S
authors: Yamauchi
mesh_terms: D005663:Furans / Q000138:chemical synthesis* / Q000737:chemistry; D017705:Lignans / Q000138:chemical synthesis* / Q000737:chemistry; D031566:Magnolia / Q000737:chemistry; D015394:Molecular Structure; D013237:Stereoisomerism
chemical_list: D005663:Furans; D017705:Lignans; C524904:magnolone; C018674:tetrahydrofuran