Crosspresentation: plasmacytoid dendritic cells are in the business.
Crosspriming and crosspresentation are performed by specialized subsets of dendritic cells. In this issue, Hoeffel et al. (2007) show that human plasmacytoid dendritic cells can crosspresent HIV-derived peptides conjugated to a lipopeptide or HIV-infected cells undergoing apoptosis.
Colonna
Marco
M
Department of Pathology and Immunology, Washington University School of Medicine, St Louis, Missouri 63110, USA. mcolonna@pathology.wustl.edu
Cella
Marina
M
D000818:Animals; D017951:Antigen Presentation / Q000276:immunology*; D003713:Dendritic Cells / Q000276:immunology*; D006678:HIV / Q000276:immunology; D015658:HIV Infections / Q000276:immunology; D006801:Humans; D007962:Leukocytes / Q000276:immunology*