title: Evidence-based approach to ablating atrial fibrillation.
abstract: Catheter ablation of atrial fibrillation (AF) has made considerable advances over the past decade. Although pulmonary vein (PV) isolation has proven to be a reliable curative treatment, especially for paroxysmal AF, it still has several issues to resolve. Because the AF mechanisms are complex and multifactorial, especially in persistent or permanent AF, they cannot be eliminated altogether by PV isolation alone. Beyond PV isolation, several other techniques have shown promise in improving the long-term success. Several recent reports comparing the superiority between AF ablation and antiarrhythmic drug therapy have shown early evidence suggesting that AF ablation warrants consideration as a first-line therapy in selected patients.
authors: Division of Cardiovascular Diseases, Cardiac Rhythm Management Laboratory, University of Alabama at Birmingham, Birmingham, AL 35294, USA. takumi-y@fb4.so-net.ne.jp
authors: Takumi
authors: T
authors: Yamada
authors: G Neal
authors: GN
authors: Kay
mesh_terms: D000889:Anti-Arrhythmia Agents / Q000627:therapeutic use; D001281:Atrial Fibrillation / Q000188:drug therapy / Q000503:physiopathology / Q000601:surgery*; D017115:Catheter Ablation; D022062:Electrophysiologic Techniques, Cardiac; D006801:Humans; D011667:Pulmonary Veins / Q000601:surgery*
chemical_list: D000889:Anti-Arrhythmia Agents