Assessment of bacille Calmette-Guérin vaccine reaction in HIV-exposed Thai infants.
We evaluated local reactions at 1, 2, and 4 months of age to bacille Calmette-Guérin vaccine given at birth to 1058 infants who were exposed to human immunodeficiency virus (HIV). No scar was discernible in 12 (12.4%) of 97 HIV-infected infants and 20 (2.1%) of 961 uninfected infants (relative risk, 5.9; 95% confidence interval, 3.0-11.8). This difference may reflect poorer immunogenicity in HIV-infected infants.
Chokephaibulkit
Kulkanya
K
Department of Pediatrics, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Chotpitayasunondh
Tawee
T
Vanprapar
Nirun
N
Waranawat
Naris
N
Mock
Philip A
PA
McConnell
Michelle S
MS
Jetswang
Bongkoch
B
Neeyapun
Kanchana
K
Tappero
Jordan W
JW
Culnane
Mary
M
D002921:Cicatrix / Q000276:immunology; D005260:Female; D015658:HIV Infections / Q000150:complications* / Q000276:immunology*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D009163:Mycobacterium bovis / Q000276:immunology*; D013785:Thailand; D014376:Tuberculosis / Q000517:prevention & control*