title: Scedosporium apiospermum traumatic endophthalmitis successfully treated with voriconazole.
abstract: We describe a case of traumatic endophthalmitis due to Scedosporium apiospermum that was successfully treated with a combination of intravitreal and systemic voriconazole. A high dose of 200 microg was used intravitreally without any apparent complications. A brief overview of voriconazole use for treatment of ocular infections is presented, and a comparison is made with antifungal agents traditionally used in ophathalmology.
authors: Department of Ophthalmology, Waikato Hospital, Hamilton, New Zealand. andre_d_z@yahoo.com
authors: Andrea
authors: A
authors: Zarkovic
authors: Stephen
authors: S
authors: Guest
mesh_terms: D000935:Antifungal Agents / Q000627:therapeutic use*; D002648:Child; D009877:Endophthalmitis / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D015821:Eye Infections, Fungal / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D015807:Eye Injuries, Penetrating / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D005260:Female; D006801:Humans; D007267:Injections; D008271:Mycetoma / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D011743:Pyrimidines / Q000627:therapeutic use*; D021681:Scedosporium / Q000302:isolation & purification*; D014230:Triazoles / Q000627:therapeutic use*; D014822:Vitreous Body; D065819:Voriconazole
chemical_list: D000935:Antifungal Agents; D011743:Pyrimidines; D014230:Triazoles; D065819:Voriconazole