title: [Rare occurrence of fulminant acid burn of the esophagus].
abstract: Peptic ulcer due to Zollinger-Ellison syndrome is a rare entity. In this case report a 55-year-old man had a medical history of esophageal reflux, vomiting, and diarrhea for 10 years. Despite continuous medication with a proton pump inhibitor, no complete recovery from symptoms was achieved. A diagnosis of gastrinoma was at first not considered. After discontinuation of the proton pump inhibitor for only a few days, the strong stimulation of the gastrinoma led to fulminant hydrochloric acid burn of the distal esophagus with iatrogenic or spontaneous perforation at the esophagogastral junction. We describe the operative treatment as a two-stage reconstruction with colon interposition and resection of the primary tumor in the duodenum.
authors: Chirurgische Klinik der TU München, Klinikum rechts der Isar, Ismaninger Strasse 22, 81675, München, Deutschland. CK1005@web.de
authors: C
authors: C
authors: Knebel
authors: R
authors: R
authors: Bumm
authors: K
authors: K
authors: Becker
authors: M
authors: M
authors: Burian
authors: J R
authors: JR
authors: Siewert
mesh_terms: D000897:Anti-Ulcer Agents / Q000008:administration & dosage; D018450:Disease Progression; D004379:Duodenal Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D004386:Duodenum / Q000473:pathology / Q000601:surgery; D016145:Endoscopy, Digestive System; D004939:Esophageal Perforation / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D016629:Esophagectomy; D004942:Esophagitis, Peptic / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D004947:Esophagus / Q000473:pathology; D005500:Follow-Up Studies; D005743:Gastrectomy; D005753:Gastric Mucosa / Q000473:pathology; D015408:Gastrinoma / Q000150:complications* / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D005764:Gastroesophageal Reflux / Q000175:diagnosis / Q000473:pathology / Q000601:surgery; D006801:Humans; D008197:Lymph Node Excision; D008207:Lymphatic Metastasis / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009336:Necrosis; D054328:Proton Pump Inhibitors; D012086:Reoperation; D016312:Treatment Refusal; D015043:Zollinger-Ellison Syndrome / Q000175:diagnosis / Q000473:pathology / Q000601:surgery
chemical_list: D000897:Anti-Ulcer Agents; D054328:Proton Pump Inhibitors