title: [Frequency and clinical characteristics of rotavirus acute gastroenteritis in children under 5 years of age treated in community practice in France].
abstract: OBJECTIVE
  The primary objective of this study was to determine the proportion of cases of gastro-enteritis due to rotavirus in children under 5 years of age consulting community physicians. A secondary objective was to compare the clinical characteristics of children with and without rotavirus acute gastro-enteritis (RV AGE).
  
  
  METHODS
  Multicentre, prospective, observational study conducted between December 2005 and May 2006. Each practitioner included 10 consecutive patients presenting with acute gastro-enteritis (AGE).
  
  
  RESULTS
  601 community practitioners, chiefly paediatricians (74.7%), included 5,062 children, 4,383 (86.6%) of whom were evaluable for analysis. The children's median age was 14 months. A rapid detection test (VIKIA((R)) Rota-Adeno - Laboratoires Biomérieux) was performed in 4,178 (95.3%) children and was rotavirus-positive in 43.7% of cases. More than 85% of children presenting with RV AGE were more than 6 months old. The difference between the severity scores of children in whom a rotavirus was detected and those in whom it was not detected was statistically significant (P<0.0001). Rotavirus AGE was significantly different (P<0.0001) from rotavirus-negative AGE in respect of vomiting (78.3% vs 51.0%), fever (76.0 vs 49.4%), weight loss (69.0 vs 43.2%), presence of signs of dehydratation (15.6 vs 3.7%) and behavioural disorders (44.4 vs 36.2%). Hospitalisation was proposed in 5.1% of cases (9.1 vs 1.8%; P<0.0001).
  
  
  CONCLUSIONS
  In this population of children under 5 years of age treated on an outpatient basis, the rapid detection test revealed the presence of rotavirus in 43.7% of cases. RV AGE appears to be significantly more severe and more often hospitalised.
authors: Urgences pédiatriques, hôpital Armand-Trousseau, APHP, 26, rue du Docteur-A.-Netter, 75571 Paris cedex 12, France. nathalie.parez@trs.aphp.fr
authors: N
authors: N
authors: Parez
authors: F-A
authors: FA
authors: Allaert
authors: T
authors: T
authors: Derrough
authors: E
authors: E
authors: Caulin
mesh_terms: D000208:Acute Disease; D002648:Child; D002675:Child, Preschool; D003710:Demography; D005194:Family Practice / Q000706:statistics & numerical data*; D005602:France / Q000453:epidemiology; D005759:Gastroenteritis / Q000453:epidemiology* / Q000382:microbiology; D006801:Humans; D016017:Odds Ratio; D011446:Prospective Studies; D012400:Rotavirus Infections / Q000453:epidemiology*