title: Organotin levels in seafood and its implications for health risk in high-seafood consumers.
abstract: Fish and fishery products are considered as the main source of organotin compounds (OTC). Unfortunately, little national contamination data is available to assess food exposure of organotins from French consumers. To provide a more accurate estimate of risks to human health, the butyltin, phenyltin and octyltin compounds sampling in four French coastal areas were measured in 159 composite samples (96 fresh and frozen fish, 28 mollusks, 14 crustaceans, 1 echinoderm, 11 canned foods, 4 smoked fish, 5 prepared seafood-based dishes) by capillary gas chromatography coupled with a microwave induced plasma atomic-emission spectrometer (CGC-MIP-AES). In these samples, butyltins were usually predominant and the range of the contamination levels was generally below those of earlier studies (fish: mean 5.6; min-max 1.1-23 microg/kg; fishery products: mean 6; min-max 0.8-14 microg/kg). Fish, especially tuna, salmon, mackerel, saithe/coalfish and cod were largely the main contributors (38%) to the total organotin exposure. With the supplementary contribution of great scallop, surimi, squid and oysters, the exposure exceeded 50% in all. However, the utmost OTC exposure was lesser than 47% of the provisional tolerable weekly intake [EFSA (European Food Safety Agency). Opinion of the Scientific Panel on Contaminants in the food chain on a request from the Commission to assess the health risks to consumers associated with exposure to organotins in foodstuffs. (Question N EFSA-Q-2003-110). The EFSA Journal, 102, 1-119, 2004. http://www.efsa.eu.int]. Nobody would exceed this limit. Finally, as this study has some limitations and since some other sources and health effects have not been clearly evaluated, it appears rational from public health and environmental viewpoints to continue to reduce the OTC levels in the environment.
authors: Agence française de sécurité sanitaire des aliments - Afssa, Unités CIME et PASER, AFSSA-LERQAP, 94706 Maisons-Alfort Cedex, France. t.guerin@afssa.fr
authors: T
authors: T
authors: Guérin
authors: V
authors: V
authors: Sirot
authors: J-L
authors: JL
authors: Volatier
authors: J-C
authors: JC
authors: Leblanc
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D004784:Environmental Monitoring; D005260:Female; D005506:Food Contamination / Q000032:analysis*; D005602:France; D006801:Humans; D008297:Male; D008875:Middle Aged; D009947:Organotin Compounds / Q000032:analysis*; D018570:Risk Assessment; D017747:Seafood; D014874:Water Pollutants, Chemical / Q000032:analysis*
chemical_list: D009947:Organotin Compounds; D014874:Water Pollutants, Chemical