title: BK Virus replication in vitro: limited effect of drugs interfering with viral uptake and intracellular transport.
abstract: BK virus is an important pathogen in kidney transplant recipients. In vitro studies demonstrated slight antiviral activity for chloroquine and nystatin. A sialic acid derivative, BTB11968, was identified as a lead compound for further development.
authors: Division of Transplantation Pathology, Department of Pathology, University of Pittsburgh, UPMC-Montefiore Hospital, Pittsburgh, PA 15213, USA. randhawapa@upmc.edu
authors: Parmjeet
authors: P
authors: Randhawa
authors: Noush Afarin
authors: NA
authors: Farasati
authors: Yuchen
authors: Y
authors: Huang
mesh_terms: D000998:Antiviral Agents / Q000737:chemistry / Q000494:pharmacology*; D001739:BK Virus / Q000187:drug effects* / Q000502:physiology; D002460:Cell Line; D002738:Chloroquine / Q000737:chemistry / Q000494:pharmacology; D006801:Humans; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D009761:Nystatin / Q000737:chemistry / Q000494:pharmacology; D014779:Virus Replication / Q000187:drug effects*
chemical_list: D000998:Antiviral Agents; D009761:Nystatin; D002738:Chloroquine