title: [Nitrogen oxide participation in the mechanism of hemodynamics reactions to tilting].
abstract: The NO-dependent mechanism of system hemodynamics reactions comprising increased system blood flow (cardiac output) and blood pressure to head-down tilting at 6, 12 and 18 degrees was studied in anaesthetized rats. Tilting of the rats with inhibited NO synthesis was shown to aggravate hypertension and elevate total peripheral resistance (TPR). Therefore, it can be concluded that NO-dependent vasodilation is involved in regulation of the arterial tone during tilting.
authors: L I
authors: LI
authors: Osadchiĭ
authors: T V
authors: TV
authors: Balueva
authors: I V
authors: IV
authors: Sergeev
mesh_terms: D000222:Adaptation, Physiological; D000818:Animals; D001783:Blood Flow Velocity / Q000187:drug effects; D004791:Enzyme Inhibitors / Q000494:pharmacology; D018475:Head-Down Tilt; D018476:Hypokinesia; D008297:Male; D019331:NG-Nitroarginine Methyl Ester / Q000494:pharmacology; D019001:Nitric Oxide Synthase / Q000037:antagonists & inhibitors; D009589:Nitrogen Oxides / Q000378:metabolism*; D051381:Rats; D017208:Rats, Wistar; D014664:Vasodilation / Q000502:physiology
chemical_list: D004791:Enzyme Inhibitors; D009589:Nitrogen Oxides; D019001:Nitric Oxide Synthase; D019331:NG-Nitroarginine Methyl Ester