Prophylactic antibiotics and surgery for primary clefts.
There are currently no evidence-based guidelines about the use of antibiotic prophylaxis in repair of cleft lip and palate. After the designation of regional cleft centres in the UK, a postal questionnaire was sent to cleft surgeons in 2004 to enquire about the use of routine antibiotic prophylaxis for primary repair of cleft lip and palate. The results showed a lack of consensus and wide disparity among centres. The findings show that there is a need for a random control clinical trial to establish national recommendations for the rational use of prophylactic antibiotics in primary cleft surgery.
Smyth
A G
AG
Clarendon Wing, Leeds General Infirmary, Belmont Grove, Leeds, West Yorkshire LS2 9NS, United Kingdom. alistair.smyth@leedsth.nhs.uk
Knepil
G J
GJ
D019072:Antibiotic Prophylaxis / Q000706:statistics & numerical data*; D002971:Cleft Lip / Q000601:surgery*; D002972:Cleft Palate / Q000601:surgery*; D006801:Humans; D007223:Infant; D019647:Oral Surgical Procedures; D013530:Surgical Wound Infection / Q000517:prevention & control; D011795:Surveys and Questionnaires