title: Case report: fusion of positron emission tomography (PET) and computed tomography (CT) images for image-guided endoscopic navigation in maxillofacial surgery: clinical application of a new technique.
abstract: BACKGROUND
  Surgery based on computed tomography (CT) data is becoming increasingly important in the head and neck region. The technique for hardware fusion between positron emission tomography (PET) and computed tomography (CT) has only been established commercially in the last 4 years. The advantages over CT alone are obvious. The surgeon is simultaneously provided with a map of anatomical as well as of functional (metabolic) details. The fused images offer improved localization of malignant lesions and improved targeting of biopsy, especially for small lesions.
  
  
  OBJECTIVE
  A new technique for image-guided tumour localization for maxillofacial surgery based on PET/CT-image fusion is described.
  
  
  METHODS
  A 78-year-old woman was admitted to this department with a tumour of the skull base. Three dimensional fusion of computed CT with positron PET images on a commercially available navigation system is described. After patient-to-image registration, a high-resolution endoscope was calibrated intraoperatively. Image-guided biopsy specimens were taken under direct visual control.
  
  
  CONCLUSIONS
  PET/CT-image fusion proved extremely helpful to navigate the endoscope to the target lesion and to identify the tumour.
authors: Department of Oral and Maxillofacial Surgery, Medical University of Graz, Austria. matthias.feichtinger@meduni-graz.at
authors: Matthias
authors: M
authors: Feichtinger
authors: Reingard Maria
authors: RM
authors: Aigner
authors: Gert
authors: G
authors: Santler
authors: Hans
authors: H
authors: Kärcher
mesh_terms: D000368:Aged; D001228:Aspergillosis / Q000473:pathology; D001706:Biopsy / Q000295:instrumentation; D019723:Endoscopes; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted; D021621:Imaging, Three-Dimensional / Q000379:methods; D008953:Models, Anatomic; D049268:Positron-Emission Tomography / Q000295:instrumentation* / Q000379:methods; D019292:Skull Base Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D025321:Surgery, Computer-Assisted / Q000379:methods*; D014057:Tomography, X-Ray Computed / Q000295:instrumentation* / Q000379:methods