Phentolamine tests and catecholamine levels in normotensive CVA patients.
Ten normotensive patients diagnosed as having a CVA had Regitine tests and urinary VMA and catecholamine determinations during the first day of hospitalization. The VMA and catecholamine levels were all within normal limits (except for one elevated VMA level) but did not correlate well with each other. The average response to phentolamine was an average drop in blood pressure of 30mm. Hg systolic and 19 mm. Hg diastolic. Mechanisms by which hypertensive states or cerebral damage might effect blood pressure are discussed. It is suggested that CNS damage might induce a vasolabile or hypersensitive state via connections and consequent alterations in the autonomic vasomotor system.
Favazza
A R
AR
Department of Psychiatry, School of Medicine, University of Missouri, Columbia 65201, USA.
D000317:Adrenergic alpha-Antagonists; D000328:Adult; D000368:Aged; D001794:Blood Pressure / Q000187:drug effects; D002395:Catecholamines / Q000652:urine*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010646:Phentolamine; D020521:Stroke / Q000175:diagnosis* / Q000503:physiopathology* / Q000652:urine; D014642:Vanilmandelic Acid / Q000652:urine
D000317:Adrenergic alpha-Antagonists; D002395:Catecholamines; D014642:Vanilmandelic Acid; D010646:Phentolamine