Mesenteric chylothrombosis in hyperlipidaemic mink.
In the familial form of hyperlipoproteinaemia type I of mink (Mustela vison), mesenteric lipogranulomas are common findings in longstanding cases. Patho-morphological studies of early stages indicated that these lipogranulomas arose from stagnant chyle. The composition of fatty acids of a newly formed mesenteric granuloma was determined, together with fatty acids in liver, plasma and the feed. The results supported the pathological observations, as the fat of the granuloma differed from that of the liver and plasma, and contained only small amounts of the endogenous arachidonic acid, while the exogenous eicosenoic acid was present in amounts comparable with the dietary fat.
Nordstoga
K
K
Norwegian School of Veterinary Science, Oslo, Norway. knut.nordstoga@veths.no
Ytrehus
B
B
Christophersen
B
B
Olivecrona
G
G
D000821:Animal Feed; D000818:Animals; D002913:Chyle; D004032:Diet / Q000662:veterinary; D017809:Fatal Outcome; D005227:Fatty Acids / Q000032:analysis*; D006099:Granuloma / Q000378:metabolism / Q000473:pathology / Q000662:veterinary*; D006949:Hyperlipidemias / Q000378:metabolism / Q000473:pathology / Q000662:veterinary*; D008055:Lipids / Q000097:blood; D008099:Liver / Q000378:metabolism; D008907:Mink / Q000378:metabolism*
D005227:Fatty Acids; D008055:Lipids