Magnetic resonance imaging (MRI) findings and neuropsychological sequelae in children after severe traumatic brain injury: the role of cerebellar lesion.
We studied the relationships between magnetic resonance imaging (MRI) findings and neuropsychological sequelae in children after severe traumatic brain injury. Twenty-three children ages 7-13 years underwent MRI assessment of brain lesion topography and volume and neuropsychological evaluations, more than 1 year after sustaining severe traumatic brain injury. Most children had lesions to the corpus callosum and frontal lobes. Total lesion volume and extent of cerebral atrophy did not impact on the neuropsychological evaluation. Additional relationships were observed: left frontal lesions with lower semantic verbal fluency, right occipital lesions with lower visual recognition task scores, dyscalculia with cerebellar lesions, and cerebellar damage with lower cognitive performances and lower visual recognition memory. This study demonstrates the significance of the cerebellum's role in neuropsychological outcomes after traumatic brain injury and the importance of the lesion depth classification in predicting functional results.
Braga
Lucia W
LW
SARAH Network, Brasilia, Brazil. luciabraga@sarah.br
Souza
Ligia N
LN
Najjar
Yana J
YJ
Dellatolas
Georges
G
D000293:Adolescent; D000367:Age Factors; D001930:Brain Injuries / Q000473:pathology* / Q000503:physiopathology / Q000523:psychology*; D002526:Cerebellar Diseases / Q000209:etiology / Q000473:pathology* / Q000523:psychology*; D002531:Cerebellum / Q000293:injuries* / Q000473:pathology* / Q000503:physiopathology; D002648:Child; D003072:Cognition Disorders / Q000209:etiology / Q000473:pathology / Q000503:physiopathology; D003337:Corpus Callosum / Q000293:injuries / Q000473:pathology / Q000503:physiopathology; D004185:Disability Evaluation; D005260:Female; D005625:Frontal Lobe / Q000293:injuries / Q000473:pathology / Q000503:physiopathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008569:Memory Disorders / Q000209:etiology / Q000473:pathology / Q000503:physiopathology; D009483:Neuropsychological Tests; D009778:Occipital Lobe / Q000293:injuries / Q000473:pathology / Q000503:physiopathology; D010364:Pattern Recognition, Visual / Q000502:physiology; D011379:Prognosis; D013064:Speech Disorders / Q000209:etiology / Q000473:pathology / Q000503:physiopathology; D014786:Vision Disorders / Q000209:etiology / Q000473:pathology / Q000503:physiopathology