[Population dynamics in tumor growth modeling].
A new approach based on local interaction between cancer and tissue cells was applied to the problem of the onset and growth of solid tumors in homogeneous tissues and effects associated with dramatic changes in tumor growth after crossing the boundary between different tissues. The characteristic sizes and growth rates of spherical tumors, the points of the beginning and the end of spherical growth, and the further development of complex structures from the spherical ones (rough interface between the tumor and the host tissue, elongate outgrowths, dendritic structures, and metastases) were inferred assuming that the reproduction rate of a population of cancer cells is a nonmonotone function of their local concentration and thus of the local curvature of the tumor surface.
Slepkov
V A
VA
Sukhovol'skiĭ
V G
VG
Khlebopros
R G
RG
D000818:Animals; D018450:Disease Progression; D006801:Humans; D008954:Models, Biological; D009369:Neoplasms / Q000378:metabolism / Q000503:physiopathology*