title: Epithelioid sarcoma of the foot with subsequent lesion in hand: metastatic lesion or second primary?
abstract: Epithelioid sarcomas (ES) are rare tumors of soft tissue that have a propensity to occur in the extremities. Epithelioid sarcomas are known to metastatise to draining lymph nodes and commonly to the lungs. Herein, a case of epithelioid sarcoma which recurred in an unusual site namely the distal phalanx of left middle finger, six months post amputation of the primary lesion in the left foot is being reported. The ipsilateral inguinal lymph node showed metastatic deposits. The tumor at both these sites had similar histology and an identical immunohistochemical (IHC) pattern showing reactivity to cytokeratin (CK), epithelial membrane antigen (EMA), vimentin (Vim) and CD34. This case is presented to record an unusual occurrence of ES in the distal phalanx of middle finger with an ES of foot. The metastasis of ES to the distal acral bones has not been documented till date.
authors: Department of Pathology, Tata Memorial Hospital, Parel, Mumbai.
authors: Dinanath P
authors: DP
authors: Khapake
authors: Nirmala A
authors: NA
authors: Jambhekar
authors: Chetan
authors: C
authors: Anchan
authors: Bhulaxmi P
authors: BP
authors: Madur
authors: Roshni F
authors: RF
authors: Chinoy
authors: M
authors: M
authors: Agarwal
authors: A
authors: A
authors: Puri
mesh_terms: D000293:Adolescent; D001859:Bone Neoplasms / Q000378:metabolism / Q000473:pathology / Q000556:secondary; D050278:Finger Phalanges / Q000473:pathology*; D005528:Foot / Q000473:pathology*; D006801:Humans; D007264:Inguinal Canal; D008198:Lymph Nodes / Q000473:pathology; D008207:Lymphatic Metastasis; D008297:Male; D016609:Neoplasms, Second Primary / Q000378:metabolism / Q000473:pathology; D012509:Sarcoma / Q000378:metabolism / Q000473:pathology / Q000556:secondary; D012983:Soft Tissue Neoplasms / Q000378:metabolism / Q000473:pathology / Q000556:secondary