Splenial corpus callosum lesion and hemifield visual color anomia associated with intracranial hypertension.
Lesions in the splenium of the corpus callosum are a rare complication of a variety of clinical conditions including ischemia, trauma, acute disseminated encephalomyelitis, infection, electrolyte imbalances, seizures, and antiepileptic drugs. This report describes a child presenting with hemifield visual color anomia, headache, and papilledema, who was found to have a midline splenial lesion on diffusion-weighted magnetic resonance imaging (MRI). Lumbar puncture revealed elevated intracranial pressure. His symptoms and MRI findings resolved quickly following treatment of his increased intracranial pressure. This is the first report describing an association between intracranial hypertension and a lesion in the splenium of the corpus callosum.
Bonkowsky
Joshua L
JL
Division of Pediatric Neurology, Department of Pediatrics, University of Utah School of Medicine, Salt Lake City, Utah 84108, USA. joshua.bonkowsky@hsc.utah.edu
Filloux
Francis M
FM
Warner
Judith E
JE
D001929:Brain Edema / Q000209:etiology / Q000503:physiopathology; D002648:Child; D003118:Color Perception; D003117:Color Vision Defects / Q000209:etiology* / Q000473:pathology* / Q000503:physiopathology; D003409:Congenital Hypothyroidism / Q000150:complications / Q000503:physiopathology; D003337:Corpus Callosum / Q000473:pathology* / Q000503:physiopathology; D006801:Humans; D019586:Intracranial Hypertension / Q000150:complications* / Q000503:physiopathology; D008279:Magnetic Resonance Imaging; D008297:Male; D009434:Neural Pathways / Q000503:physiopathology*; D013129:Spinal Puncture; D014793:Visual Cortex / Q000503:physiopathology*; D014794:Visual Fields