title: Experimental infectious bursal disease in the ostrich (Struthio camelus).
abstract: Clinically severe disease was produced in ostriches aged 4 weeks by oral infection with a virulent strain of infectious bursal disease virus (vIBDV), namely strain Faragher 52/70. Four days after infection the birds were humanely killed and tissue samples, including thymus, bursa of Fabricius (BF), brain and kidney were collected for examination. Histopathologically, the thymus and BF showed severe lymphoid depletion and necrosis, while immunolabelling with a polyclonal antibody demonstrated abundant viral antigen.
authors: UNESP Laboratório de Virologia, Departamento de Apoio, Produção e Saúde Animal.
authors: A R
authors: AR
authors: Mendes
authors: Laboratório de Patologia, Departamento de Clínica, Cirurgia e Reprodução Animal.
authors: M C R
authors: MCR
authors: Luvizotto
authors: Laboratório de Patologia, Departamento de Clínica, Cirurgia e Reprodução Animal.
authors: H F
authors: HF
authors: Ferrari
authors: Centro Experimental de Zootecnia, DAPSA do Curso de Medicina Veterinária, Rua Clóvis Pestana 793, CEP 16.050-680, Araçatuba, São Paulo, Brazil.
authors: M G
authors: MG
authors: Neto
authors: UNESP Laboratório de Virologia, Departamento de Apoio, Produção e Saúde Animal. Electronic address: tcardoso@fmva.unesp.br.
authors: T C
authors: TC
authors: Cardoso
mesh_terms: D000818:Animals; D000956:Antigens, Viral / Q000302:isolation & purification; D001715:Bird Diseases / Q000276:immunology / Q000473:pathology / Q000821:virology*; D018175:Birnaviridae Infections / Q000276:immunology / Q000473:pathology / Q000662:veterinary* / Q000821:virology*; D001921:Brain / Q000473:pathology / Q000821:virology; D002060:Bursa of Fabricius / Q000473:pathology / Q000821:virology; D007243:Infectious bursal disease virus; D007668:Kidney / Q000473:pathology / Q000821:virology; D023421:Models, Animal; D009336:Necrosis; D020310:Struthioniformes; D013950:Thymus Gland / Q000473:pathology / Q000821:virology
chemical_list: D000956:Antigens, Viral