title: Ethical issues in adolescent and parent informed consent for pediatric asthma research participation.
abstract: This article reviews the empirical literature related to knowledge, competence, volition, and financial compensation in the biomedical research decision-making of children, adolescents, and parents. Research findings indicate there are differences in adolescent and parent understanding and appreciation of research risks and procedures, that opinions about decision-making authority and physician influence for research participation are different in adolescents and parents, and that financial compensation can be a salient factor in the research-related decision-making process. Pediatric asthma researchers can consider these psychological factors involved in adolescent and parent research participation decision-making processes to develop effective informed consent procedures.
authors: Department of Psychology, University of Massachusetts, Amherst, MA 01003, USA. dscherer@psych.umass.edu
authors: David G
authors: DG
authors: Scherer
authors: Robert D
authors: RD
authors: Annett
authors: Janet L
authors: JL
authors: Brody
mesh_terms: D000293:Adolescent; D001249:Asthma / Q000628:therapy*; D035843:Biomedical Research / Q000941:ethics*; D002648:Child; D003657:Decision Making; D032984:Ethics, Research; D006801:Humans; D007258:Informed Consent / Q000941:ethics*; D016743:Mental Competency / Q000523:psychology; D033282:Parental Consent / Q000941:ethics; D010358:Patient Participation / Q000523:psychology; D010465:Perception; D000297:Psychology, Adolescent; D018570:Risk Assessment; D014836:Volition