Vasculogenesis, angiogenesis, and arteriogenesis: mechanisms of blood vessel formation and remodeling.
In this review, the concept of oxygen homeostasis will be presented as an organizing principle for discussion of the phylogeny, ontogeny, physiology, and pathology of blood vessel formation and remodeling, with a focus on molecular mechanisms and potential therapeutic applications.
Semenza
Gregg L
GL
Vascular Biology Program, Institute for Cell Engineering; Department of Pediatrics, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA. gsemenza@jhmi.edu
D000818:Animals; D001808:Blood Vessels / Q000254:growth & development; D006706:Homeostasis / Q000502:physiology; D006801:Humans; D000860:Hypoxia; D007511:Ischemia; D009389:Neovascularization, Pathologic / Q000503:physiopathology*; D018919:Neovascularization, Physiologic / Q000502:physiology*; D010100:Oxygen / Q000502:physiology
D010100:Oxygen