Hypotonic and hyporesponsive episodes after diptheria-tetanus-acellular pertussis vaccination.
Administration of the discontinued diphtheria-pertussis-tetanus vaccine was occasionally associated with a hypotonic-hyporesponsive episode in infants. The whole bacterial cell pertussis component was the likely culprit. For this reason, an acellular pertussis component was developed and incorporated into a new vaccine commonly called diptheria-tetanus-acellular pertussis (DTaP). Administration of DTaP vaccine has been followed by remarkably few hypotonic or hyporesponsive episodes. This report describes one of these unusual events.
Cherry
James D
JD
David Geffen School of Medicine, Mattel Children's Hospital at UCLA, Los Angeles, CA, USA.
Karam
Albert G
AG
D022681:Diphtheria-Tetanus-acellular Pertussis Vaccines / Q000009:adverse effects*; D005260:Female; D006801:Humans; D007022:Hypotension; D007223:Infant
D022681:Diphtheria-Tetanus-acellular Pertussis Vaccines