Mediastinal mass mimicking a tumor in a patient with bladder cancer after Bacillus Calmette-Guerin treatment.
We describe the case of a 78-year-old male with bladder cancer who developed a mediastinal mass after intravesical immunotherapy with live Mycobacterium bovis BCG. The clinical diagnosis was mediastinal tumor suggestive for lymphoma. However, cultures of the biopsy specimens grew an acid-fast organism, which was identified as M. bovis BCG. To the best of our knowledge, this is the first reported case in which a post-instillation BCG infection induced a mediastinal mass that mimicked a tumor in a patient with bladder cancer.
Somoskovi
A
A
Wadsworth Center, New York State Department of Health, Albany, NY, USA.
Carlyn
C
C
Dormandy
J
J
Salfinger
M
M
D000283:Administration, Intravesical; D000368:Aged; D001500:BCG Vaccine / Q000009:adverse effects* / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008477:Mediastinal Diseases / Q000175:diagnosis / Q000209:etiology* / Q000473:pathology; D009163:Mycobacterium bovis; D014376:Tuberculosis / Q000175:diagnosis / Q000382:microbiology / Q000473:pathology; D001749:Urinary Bladder Neoplasms / Q000188:drug therapy*
D001500:BCG Vaccine