title: Pathogen virulence factors as molecular probes of basic plant cellular functions.
abstract: To successfully colonize plants, pathogens have evolved a myriad of virulence factors that allow them to manipulate host cellular pathways in order to gain entry into, multiply and move within, and eventually exit the host for a new infection cycle. In the past few years, substantial progress has been made in characterizing the host targets of viral and bacterial virulence factors, providing unique insights into basic plant cellular processes such as gene silencing, vesicle trafficking, hormone signaling, and innate immunity. Identification of the host targets of additional pathogen virulence factors promises to continue shedding light on fundamental cellular mechanisms in plants, thus enhancing our understanding of plant signaling, metabolism, and cell biology.
authors: Department of Energy Plant Research Laboratory, Michigan State University, East Lansing, MI 48824, USA.
authors: Elena Bray
authors: EB
authors: Speth
authors: Young Nam
authors: YN
authors: Lee
authors: Sheng Yang
authors: SY
authors: He
mesh_terms: D001426:Bacterial Proteins / Q000378:metabolism / Q000502:physiology; D001692:Biological Transport; D002736:Chloroplasts / Q000502:physiology; D005656:Fungal Proteins / Q000378:metabolism / Q000502:physiology; D018506:Gene Expression Regulation, Plant; D007113:Immunity, Innate / Q000502:physiology; D020935:MAP Kinase Signaling System; D059828:Plant Cells; D010944:Plants / Q000378:metabolism / Q000382:microbiology*; D046988:Proteasome Endopeptidase Complex / Q000378:metabolism; D034622:RNA Interference; D016601:RNA-Binding Proteins / Q000378:metabolism / Q000502:physiology; D014764:Viral Proteins / Q000378:metabolism / Q000502:physiology; D037521:Virulence Factors / Q000378:metabolism / Q000502:physiology*
chemical_list: D001426:Bacterial Proteins; D005656:Fungal Proteins; D016601:RNA-Binding Proteins; D014764:Viral Proteins; D037521:Virulence Factors; D046988:Proteasome Endopeptidase Complex; C061553:ATP dependent 26S protease