Reliéva, a Mahonia aquifolium extract for the treatment of adult patients with atopic dermatitis.
This clinical study was conducted to determine the efficacy and safety of Reliéva cream in adult patients with atopic dermatitis (eczema). This was an open-label trial in 42 patients with atopic dermatitis treated for 12 weeks with Reliéva cream (a homeopathic product containing Psorberine, a proprietary Mahonia aquifolium extract). Efficacy and safety was assessed using Eczema Area and Severity Index scores and a Subject Reported Evaluation of Treatment. The results showed significant (P < 0.05) improvements with respect to Eczema Area and Severity Index scores by comparison to subjects' baseline scores. In addition, subjects responding to a posttreatment evaluation questionnaire indicated a substantial benefit when rating effectiveness, itching, and appearance as a result of using the study preparation. Reliéva cream appears to be a safe and effective treatment for adult patients with atopic dermatitis (eczema).
Donsky
Howard
H
Dermatology and Cosmetic Center of Rochester, Rochester, NY, USA.
Clarke
Don
D
D000279:Administration, Cutaneous; D000328:Adult; D000368:Aged; D003876:Dermatitis, Atopic / Q000188:drug therapy*; D005260:Female; D006801:Humans; D008081:Liposomes; D028143:Mahonia / Q000737:chemistry*; D008297:Male; D008875:Middle Aged; D009824:Ointments; D008517:Phytotherapy; D010936:Plant Extracts / Q000009:adverse effects / Q000627:therapeutic use*; D011537:Pruritus / Q000188:drug therapy / Q000209:etiology; D012720:Severity of Illness Index
D008081:Liposomes; D009824:Ointments; D010936:Plant Extracts