title: Antimicrobial stewardship stabilizes resistance patterns in a behavioral health setting.
abstract: BACKGROUND
  Connecticut Valley Hospital, an inpatient tertiary care psychiatric hospital, identified a significant increase in the antimicrobial resistance of E. coli to multiple antibiotics including quinolones.
  
  
  OBJECTIVE
  To improve the resistance profile of E. coli by better managing the usage of quinolones at this hospital.
  
  
  METHODS
  Education was provided to physicians, nurses and pharmacists regarding antibiotic usage, restriction and prior approval of quinolones. Further education was provided when the program was determined to be effective, and continued for another year.
  
  
  RESULTS
  A significant reduction of the prescription of quinolones was demonstrated. The resistance patterns of E. coli to quinolones and other antibiotics stabilized.
  
  
  CONCLUSIONS
  In this psychiatric hospital inpatient population, antimicrobial stewardship proved to be an effective tool in managing antibiotic utilization and stabilizing antimicrobial resistance among E. coli isolates.
authors: Lemuel Shattuck Hospital, Jamaica Plain, MA 02130-3735, USA. Kenneth.Freedman@state.ma.us
authors: Kenneth
authors: K
authors: Freedman
authors: Bharat
authors: B
authors: Kolluri
authors: Laurie
authors: L
authors: Neudecker
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D003237:Connecticut; D011307:Drug Prescriptions / Q000706:statistics & numerical data*; D024881:Drug Resistance, Bacterial; D004363:Drug Utilization / Q000706:statistics & numerical data*; D017723:Drug Utilization Review; D004926:Escherichia coli / Q000187:drug effects*; D006778:Hospitals, Psychiatric; D006801:Humans; D017053:Infection Control / Q000379:methods*; D010606:Pharmacy and Therapeutics Committee; D017410:Practice Guidelines as Topic; D015363:Quinolones
chemical_list: D000900:Anti-Bacterial Agents; D015363:Quinolones