Hederyne A, a new antimicrobial polyacetylene from galls of Hedera rhombea Bean.
A new C(17)-polyacetylene, named hederyne A (1), has been isolated from the MeOH extract of galls of Hedera rhombea Bean (Araliaceae), together with two known polyacetylenes, falcarindiol (2) and 11,12-dehydrofalcarinol (3). The structure elucidation of 1 was achieved by NMR, MS, IR, and UV spectroscopy. Hederyne A (1) was a new C(17)-diacetylene containing 1,3-propanediol and exhibited selective antimicrobial activity against Micrococus luteus.
Yamazoe
Sayumi
S
Graduate School of Life and Environmental Sciences, University of Tsukuba, Tsukuba, Ibaraki, Japan.
Hasegawa
Koji
K
Ito
Junji
J
Mikami
Yuzuru
Y
Shigemori
Hideyuki
H
D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D027481:Araliaceae / Q000737:chemistry*; D008826:Microbial Sensitivity Tests; D016982:Micrococcus luteus / Q000187:drug effects; D053279:Polyynes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D013057:Spectrum Analysis / Q000379:methods
D000900:Anti-Bacterial Agents; C528735:hederyne A; D053279:Polyynes