Preparation of aromatic beta-selenolactams and their bioactivities as agricultural chemicals.
The purpose of this study was to investigate the possibility of aromatic beta-selenolactams being used in agricultural chemicals. A series of beta-selenolactams with aromatic substituents at the 1-, 2- and 3-positions were synthesized and their bioactivities were evaluated. Acarianicidal and insecticidal activity against common destructive insects, antibacterial activity against seven common plant pathogens, and plant growth activity of typical food crops were investigated. We found that introduction of 4-chloro and 4-methyl groups on 2- or 3-phenyl groups of the beta-selenolactam ring brought about acarianicidal activity against adults and eggs of Plutella xylostella. However, except for moderate to weak effect on fatality of Culex pipiens molestus Forskal, insecticidal activity against two other kinds of insects, antibacterial activity against plant pathogens, and activity on plant growth regulation were not detected among the beta-selenolactam derivatives.
Kimura
Mitsutoshi
M
Department of Chemistry, Faculty of Engineering, Gifu University, Yanagido 1-1, Gifu, Japan. kimura.mitsutoshi@kao.co.jp
Ishihara
Hideharu
H
Kato
Shinzi
S
D000053:Acari / Q000187:drug effects / Q000254:growth & development; D016573:Agrochemicals / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D000818:Animals; D003500:Cyclization; D006841:Hydrocarbons, Aromatic / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D007313:Insecta / Q000187:drug effects / Q000254:growth & development; D007306:Insecticides / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D015394:Molecular Structure; D016566:Organoselenium Compounds / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D047090:beta-Lactams / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology
D016573:Agrochemicals; D006841:Hydrocarbons, Aromatic; D007306:Insecticides; D016566:Organoselenium Compounds; D047090:beta-Lactams