Desensitizing efficacy of a new toothpaste containing 5.5% potassium citrate: a 4-week clinical study.
OBJECTIVE
To evaluate the desensitizing capabilities of a new toothpaste containing 5.5% potassium citrate (Colgate Sensitive Multi Protection Toothpaste) to another toothpaste containing 3.75% potassium chloride (Sensodyne Total Care F Toothpaste).


METHODS
A 4-week clinical study was conducted in 75 subjects at the University of Rome, at Tor Vergata, in Rome, Italy, using a double blind, stratified, two treatment design. Tactile sensitivity as well as air blast sensitivity assessment was used to compare the efficacy of the two products.


RESULTS
There was no statistically significant difference in tactile sensitivity scores and air blast sensitivity scores between the tested toothpastes at baseline, 2 weeks and 4 weeks. Both toothpastes provided statistically significant improvement in tactile sensitivity scores and air blast sensitivity scores after 2 weeks of use and 4 weeks of use as compared to baseline scores.
Docimo
Rafaella
R
School of Dental Hygiene, University of Rome at Tor Vergata, Italy.
Montesani
Luigi
L
Maturo
Paolo
P
Costacurta
Micaela
M
Bartolino
Martina
M
DeVizio
William
W
Zhang
Yun Po
YP
Dibart
Serge
S
D000293:Adolescent; D000328:Adult; D000368:Aged; D000700:Analgesics / Q000627:therapeutic use*; D045424:Complex Mixtures / Q000737:chemistry / Q000627:therapeutic use; D003807:Dentin Sensitivity / Q000188:drug therapy*; D004338:Drug Combinations; D005260:Female; D005459:Fluorides / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged; D009566:Nitrates / Q000627:therapeutic use; D010710:Phosphates / Q000627:therapeutic use; D011189:Potassium Chloride / Q000627:therapeutic use*; D019357:Potassium Citrate / Q000627:therapeutic use*; D017680:Potassium Compounds / Q000737:chemistry / Q000627:therapeutic use*; D014100:Toothpastes / Q000737:chemistry / Q000627:therapeutic use*
D000700:Analgesics; D045424:Complex Mixtures; D004338:Drug Combinations; D009566:Nitrates; D010710:Phosphates; D017680:Potassium Compounds; C097427:Sensodyne; D014100:Toothpastes; C444700:colgate sensitive; D011189:Potassium Chloride; D019357:Potassium Citrate; D005459:Fluorides