title: [Drug information brochure for patients undergoing FOLFOX 4 chemotherapy based on survey of adverse reactions].
abstract: We have been collecting data on the adverse reaction of FOLFOX 4 chemotherapy in our hospital from April 2005 to October retrospectively, by electronic clinical records. A retrospective study of 123 patients receiving FOLFOX 4 for advanced colorectal cancer was conducted. Survey results showed high incidences of hemotoxicity (52.8%), chronic sensory neuropathy (16.2%) and allergic reactions (15.4%). In the initial FOLFOX 4 therapy, appetite loss (60.1%), vomiting (19.5%) and acute sensory neuropathy (33.3%) were observed. We prepared a brochure in order to minimize inter-individual differences in pharmaceutical care and drug consultation by clinical pharmacists and to ensure the accurate understanding of patients. We feel sure that this kind of activity will help us to provide better pharmaceutical care for patients.
authors: Department of Pharmacy, Cancer Institute Hospital.
authors: Hiroshi
authors: H
authors: Imada
authors: Kazuyoshi
authors: K
authors: Kawakami
authors: Tomoko
authors: T
authors: Hiraoka
authors: Shutaro
authors: S
authors: Higuchi
authors: Gou
authors: G
authors: Takahashi
authors: Takeshi
authors: T
authors: Aoyama
authors: Eiji
authors: E
authors: Shinozaki
authors: Mitsukuni
authors: M
authors: Suenaga
authors: Satoshi
authors: S
authors: Matsuzaka
authors: Toshihiro
authors: T
authors: Hama
mesh_terms: D000328:Adult; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects*; D015179:Colorectal Neoplasms / Q000188:drug therapy; D004346:Drug Information Services; D005260:Female; D005472:Fluorouracil / Q000009:adverse effects; D006801:Humans; D002955:Leucovorin / Q000009:adverse effects; D008297:Male; D008875:Middle Aged; D009944:Organoplatinum Compounds / Q000009:adverse effects; D012189:Retrospective Studies
chemical_list: D009944:Organoplatinum Compounds; D002955:Leucovorin; D005472:Fluorouracil