title: Thermodynamics of mechanical transduction of surface confined receptor/ligand reactions.
abstract: Chemomechanics of surface stress is discussed in terms of interfacial thermodynamics. In the first section the paper shows how to quantitatively describe the chemical equilibrium of a receptor/ligand binding reaction confined at a solid-liquid interface and how the overall work of the reaction splits into chemical and surface work, that appears as a surface pressure. In the second section this thermodynamic model is applied to describe the experimental results of microcantilever bending induced by DNA hybridization occurring onto one of its faces.
authors: INSTM and Chemistry for Technologies Laboratory, University of Brescia, via Branze 38, 25123 Brescia, Italy. paolo.bergese@ing.unibs.it
authors: Paolo
authors: P
authors: Bergese
authors: Giulio
authors: G
authors: Oliviero
authors: Ivano
authors: I
authors: Alessandri
authors: Laura E
authors: LE
authors: Depero
mesh_terms: D000937:Antigen-Antibody Reactions; D001665:Binding Sites; D004247:DNA / Q000737:chemistry*; D017403:In Situ Hybridization; D008024:Ligands; D011506:Proteins / Q000737:chemistry*; D013499:Surface Properties; D013816:Thermodynamics
chemical_list: D008024:Ligands; D011506:Proteins; D004247:DNA