title: Perioperative management of pediatric patients with craniosynostosis.
abstract: Craniosynostosis, premature closures of the skull sutures, results in dysmorphic features if left untreated. Brain growth and cognitive development may also be impacted. Craniosynostosis repair is usually performed in young infants and has its perioperative challenges. This article provides background information about the different forms of craniosynostosis, with an overview of associated anomalies, genetic influences, and their connection with cognitive function. It also discusses the anesthetic considerations for perioperative management, including blood-loss management and strategies to reduce homologous blood transfusions.
authors: Department of Anesthesiology and Perioperative Medicine, Oregon Health and Sciences University, 3181 SW Sam Jackson Park Road, Portland, OR 97201, USA. kohj@ohsu.ed
authors: Jeffrey L
authors: JL
authors: Koh
authors: Heike
authors: H
authors: Gries
mesh_terms: D000758:Anesthesia; D016063:Blood Loss, Surgical; D001803:Blood Transfusion / Q000379:methods* / Q000592:standards; D001921:Brain / Q000254:growth & development; D003071:Cognition / Q000502:physiology; D003393:Cranial Sutures / Q000254:growth & development / Q000601:surgery; D003398:Craniosynostoses / Q000145:classification / Q000235:genetics / Q000601:surgery*; D006801:Humans; D007223:Infant; D019990:Perioperative Care; D017410:Practice Guidelines as Topic; D065227:Transfusion Reaction