New C-secosteroids from the gorgonian Tripalea clavaria.
Seven new C-secosteroids were isolated from the gorgonian Tripalea clavaria collected from the South Atlantic. These compounds have a Delta(5), 9,11-secosteroid nucleus together with a 22S hydroxyl group. The absolute configuration of the 22-hydroxyl group was determined with the help of COSY spectra of the Mosher esters of the compounds.
Rodríguez Brasco
María F
MF
UMYMFOR-Departamento de Química Orgánica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Ciudad Universitaria, Pab 2 (1428), Buenos Aires, Argentina.
Genzano
Gabriel N
GN
Palermo
Jorge A
JA
D000818:Animals; D037421:Anthozoa / Q000737:chemistry*; D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D000935:Antifungal Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D001412:Bacillus subtilis / Q000187:drug effects; D020171:Botrytis / Q000187:drug effects; D002176:Candida albicans / Q000187:drug effects; D004926:Escherichia coli / Q000187:drug effects; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D012632:Secosteroids / Q000737:chemistry* / Q000302:isolation & purification* / Q000494:pharmacology; D013211:Staphylococcus aureus / Q000187:drug effects
D000900:Anti-Bacterial Agents; D000935:Antifungal Agents; D012632:Secosteroids