title: Solid-phase based synthesis of jasplakinolide analogs by intramolecular azide-alkyne cycloadditions.
abstract: The synthesis of a focused library of jasplakinolide analogs with a 1,2,3-triazole in place of an E-configured double bond is described, featuring the Cu(I) catalyzed azide-alkyne cycloaddition reaction as an efficient macrocyclization tool.
authors: Universität Dortmund, Fachbereich Chemie, Otto-Hahn-Str. 6, D-44221 Dortmund, Germany.
authors: Tai-Shan
authors: TS
authors: Hu
authors: René
authors: R
authors: Tannert
authors: Hans-Dieter
authors: HD
authors: Arndt
authors: Herbert
authors: H
authors: Waldmann
mesh_terms: D000480:Alkynes / Q000737:chemistry*; D001386:Azides / Q000737:chemistry*; D047630:Depsipeptides / Q000138:chemical synthesis*; D014230:Triazoles / Q000138:chemical synthesis*
chemical_list: D000480:Alkynes; D001386:Azides; D047630:Depsipeptides; D014230:Triazoles; C057531:jasplakinolide