title: Occurrence and spread of multiresistant Salmonella Typhimurium DT104 in Danish animal herds investigated by the use of DNA typing and spatio-temporal analysis.
abstract: In the investigation we report the occurrence and spread of multiresistant Salmonella Typhimurium phage type (DT) 104 in 174 known Danish animal herds infected between 1996 and 2003. We applied PFGE, plasmid analysis and spatio-temporal analysis for a description of the development and spread of infection among herds. The results showed that in Denmark DT104 are mainly spread by trade of animals; however, horizontal spread of DT104 is also important and the risk of an animal herd becoming infected increased with the proximity in time and space to a DT104-infected herd. Based on these results, it is recommended that specific actions are taken to limit the risk of horizontal spread of DT104 from newly infected herds.
authors: National Food Institute, The Technical University of Denmark, Copenhagen, Denmark. Marianne.Skov@ouh.regionsyddanmark.dk
authors: M N
authors: MN
authors: Skov
authors: J S
authors: JS
authors: Andersen
authors: D L
authors: DL
authors: Baggesen
mesh_terms: D000818:Animals; D000829:Animals, Domestic / Q000382:microbiology; D004269:DNA, Bacterial / Q000032:analysis; D003718:Denmark / Q000453:epidemiology; D018562:Disease Transmission, Infectious; D010957:Plasmids; D012481:Salmonella Infections, Animal / Q000453:epidemiology / Q000382:microbiology* / Q000635:transmission*; D012486:Salmonella typhimurium / Q000145:classification*
chemical_list: D004269:DNA, Bacterial