Changes in serum eosinophil cationic protein levels after exercise challenge in asthmatic children.
The aim of the present study was to assess the relationship between serum eosinophil cationic protein levels and the severity of exercise-induced bronchoconstriction in asthmatic children. The 48 asthmatic children were divided into exercise-induced bronchoconstriction group and non-exercise-induced bronchoconstriction group. In the exercise-induced bronchoconstriction group, the post-exercise serum eosinophil cationic protein levels were significantly increased as compared with the pre-exercise serum eosinophil cationic protein levels. These results suggested that eosinophil cationic protein may serve as a possible contributor to the pathophysiology of exercise-induced bronchoconstriction in asthmatic children.
Hsieh
Chia-Chang
CC
First Department of Internal Medicine, School of Medicine, Kyorin University, Tokyo, Japan.
Goto
Hajime
H
Kobayashi
Hiroyuki
H
Chow
Wen-Chi
WC
Peng
Wen-Huang
WH
Tang
Ren-Bin
RB
D000293:Adolescent; D001249:Asthma / Q000503:physiopathology*; D001250:Asthma, Exercise-Induced / Q000503:physiopathology; D015415:Biomarkers / Q000097:blood; D002648:Child; D047150:Eosinophil Cationic Protein / Q000097:blood*; D005260:Female; D006801:Humans; D008297:Male; D011446:Prospective Studies
D015415:Biomarkers; D047150:Eosinophil Cationic Protein