[Crohn's disease and cancer risk. Incidence/prevalence, clinical characteristics, and potential prevention strategies].
Epidemiologic data concerning the risk for colorectal cancer in ulcerative colitis are based on a variety of large and well-conducted cohort studies. Guidelines for tumor prevention have been published by the German Gastroenterology Society (DGVS) in 2004. By contrast, the risk constellations in Crohn's disease are less clear and guidelines are lacking. Based on a recent literature search (PubMed March 2007), the published data predominantly expressed as relative risk and/or standardized incidence/mortality ratio are critically reviewed with recommendations for tumor prevention strategies based on individual risk constellations.
Allgayer
Hubert
H
Schwerpunkt Verdauungs- und Stoffwechselerkrankungen,, Rehaklinik ob der Tauber, Bad Mergentheim, Akademisches Lehrkrankenhaus der Universität Heidelberg.
Holtmeier
Wolfgang
W
Dietrich
Christoph F
CF
D000328:Adult; D015331:Cohort Studies; D015179:Colorectal Neoplasms / Q000175:diagnosis / Q000453:epidemiology / Q000401:mortality / Q000517:prevention & control; D003424:Crohn Disease / Q000150:complications / Q000175:diagnosis / Q000453:epidemiology* / Q000401:mortality; D003430:Cross-Sectional Studies; D005260:Female; D005858:Germany / Q000453:epidemiology; D006801:Humans; D015994:Incidence; D007414:Intestinal Neoplasms / Q000175:diagnosis / Q000453:epidemiology* / Q000401:mortality / Q000517:prevention & control; D007421:Intestine, Small; D008297:Male; D011446:Prospective Studies; D012307:Risk Factors; D013223:Statistics as Topic; D016019:Survival Analysis