A novel mycolactone toxin obtained by biosynthetic engineering.
Hong
Hui
H
Sanger Building, Department of Biochemistry, University of Cambridge, 80 Tennis Court Road, Cambridge CB2 1QW, UK.
Stinear
Tim
T
Porter
Jessica
J
Demangel
Caroline
C
Leadlay
Peter F
PF
D001427:Bacterial Toxins / Q000096:biosynthesis* / Q000737:chemistry* / Q000494:pharmacology; D002853:Chromatography, Liquid; D006801:Humans; D007166:Immunosuppressive Agents / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology; D007376:Interleukin-2 / Q000096:biosynthesis / Q000378:metabolism; D019169:Jurkat Cells; D018942:Macrolides; D015394:Molecular Structure; D053719:Tandem Mass Spectrometry
D001427:Bacterial Toxins; D007166:Immunosuppressive Agents; D007376:Interleukin-2; D018942:Macrolides; C117218:mycolactone