Ischemic stroke and peripheral arterial thromboembolism in a patient with Crohn's disease: a case presentation.
Both ischemic stroke and peripheral arterial thromboembolism have been described as extraintestinal complications of inflammatory bowel disease. Here, we present the first case with direct cooccurrence of ischemic stroke and peripheral thromboembolism in a 39-year-old patient with Crohn's disease. A pathophysiological model explaining this cooccurrence as well as the significance of prothrombotic risk factors ("hypercoaguable state") in the setting of inflammatory bowel disease and stroke are discussed.
Freilinger
Tobias
T
Department of Neurology, Klinikum Grosshadern, Ludwig-Maximilians-University, Marchioninistr. 15, 81377 Munich, Germany. tobias.freilinger@med.uni-muenchen.de
Riedel
Eva
E
Holtmannspötter
Markus
M
Dichgans
Martin
M
Peters
Nils
N
D000925:Anticoagulants / Q000627:therapeutic use; D001241:Aspirin / Q000627:therapeutic use; D001772:Blood Cell Count; D001777:Blood Coagulation / Q000502:physiology; D001853:Bone Marrow / Q000473:pathology; D002545:Brain Ischemia / Q000150:complications*; D003424:Crohn Disease / Q000097:blood / Q000150:complications*; D004562:Electrocardiography; D015716:Electrocardiography, Ambulatory; D006493:Heparin / Q000627:therapeutic use; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use; D020769:Posterior Cerebral Artery / Q000473:pathology; D012306:Risk; D020521:Stroke / Q000150:complications* / Q000209:etiology; D013923:Thromboembolism / Q000097:blood / Q000150:complications* / Q000000981:diagnostic imaging; D014057:Tomography, X-Ray Computed; D018616:Ultrasonography, Doppler, Duplex
D000925:Anticoagulants; D010975:Platelet Aggregation Inhibitors; D006493:Heparin; D001241:Aspirin