[The course of pregnancy and delivery and the state of the newborns after genetic amniocentesis].
OBJECTIVE
The risk of fetal loss after amniocentesis is 0.2-1%. The aim of the study was to compare the course of pregnancy and delivery and the state of the newborn in patients after genetic amniocentesis and in the control group.


METHODS
783 patients who underwent amniocentesis at the Department of Obstetrics of Medical University of Gdansk in 1996-2003 and 221 women who did not undergo amniocentesis.


RESULTS
Fetal loss occurred in 8 pregnancies (3.8%) after amniocentesis and in 12 (5.4%) p=0.37 in the control group. There was no significant statistical difference between the amniocentesis group and the control group comparing complications during pregnancy such as gestational diabetes mellitus, pregnancy induced hypertension, urinary tract infections. Cesarean section was more often performed in the amniocentesis group than in the control group, statistical difference p=0.003. Most often (28.09%) there was an elective cesarean section because of advanced maternal age without any obstetrician cause. The frequency of pneumonia, respiratory infections and congenital malformations in the first weeks of life was more frequent in the amniocetesis group.


CONCLUSIONS
Invasive prenatal diagnosis has no influence of the frequency of complications during pregnancy and delivery.
Ciach
Katarzyna
K
Katedra Perinatologii Klinika Połoznictwa AM w Gdańsku. stefa@microsun.com.pl
Preis
Krzysztof
K
Swiatkowska-Freund
Małgorzata
M
Wydra
Dariusz
D
D000022:Abortion, Spontaneous / Q000453:epidemiology; D000328:Adult; D000649:Amniocentesis / Q000009:adverse effects* / Q000706:statistics & numerical data; D002585:Cesarean Section / Q000706:statistics & numerical data; D015331:Cohort Studies; D016640:Diabetes, Gestational / Q000453:epidemiology; D005260:Female; D006801:Humans; D046110:Hypertension, Pregnancy-Induced / Q000453:epidemiology; D007231:Infant, Newborn; D008423:Maternal Age; D007744:Obstetric Labor Complications / Q000453:epidemiology*; D007752:Obstetric Labor, Premature / Q000453:epidemiology; D011044:Poland / Q000453:epidemiology; D011247:Pregnancy; D011256:Pregnancy Outcome / Q000453:epidemiology*; D012189:Retrospective Studies; D012307:Risk Factors; D014552:Urinary Tract Infections / Q000453:epidemiology; D016387:Women's Health