Two-dimensional J-spectra with absorption-mode lineshapes.
Two-dimensional J-spectroscopy offers the possibility of a complete separation of chemical shifts and J-couplings. However, the usefulness of the experiment is considerably reduced by the fact that peaks in the spectra have the phase-twist lineshape. We present a simple new spectroscopic method for recording J-spectra in which the peaks are both in the absorption mode and retain their natural intensities, albeit at the cost of a considerable reduction in the signal-to-noise ratio. No special data-processing is required. The method is tested on quinine, and the steroid dehydroisoandrosterone.
Pell
Andrew J
AJ
University of Cambridge, Department of Chemistry, Cambridge, UK.
Keeler
James
J
D000465:Algorithms; D003198:Computer Simulation; D003687:Dehydroepiandrosterone / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D008956:Models, Chemical; D008958:Models, Molecular; D011803:Quinine / Q000737:chemistry*
D003687:Dehydroepiandrosterone; D011803:Quinine