title: The modified checklist for autism in toddlers: a follow-up study investigating the early detection of autism spectrum disorders.
abstract: Autism spectrum disorders (ASD) often go undetected in toddlers. The Modified Checklist for Autism in Toddlers (M-CHAT) was used to screen 3,793 children aged 16-30 months from low- and high-risk sources; screen positive cases were diagnostically evaluated. Rescreening was performed on 1,416 children aged 42-54 months. Time 1 Positive Predictive Value (PPV) was .36 for the initial screening and .74 for the screening plus follow-up telephone interview; values were similar for Time2 PPV. When separating referral sources, PPV was low for the low-risk sample but acceptable with the followup telephone interview. Children with ASD from the low-risk and high-risk samples were highly similar. Results indicate that the M-CHAT continues to be a promising instrument for the early detection of ASD.
authors: Department of Psychology, University of Connecticut, 406 Babbidge Rd., Storrs, CT 06269-1020, USA. jamie_kleinman@yahoo.com
authors: Jamie M
authors: JM
authors: Kleinman
authors: Diana L
authors: DL
authors: Robins
authors: Pamela E
authors: PE
authors: Ventola
authors: Juhi
authors: J
authors: Pandey
authors: Hilary C
authors: HC
authors: Boorstein
authors: Emma L
authors: EL
authors: Esser
authors: Leandra B
authors: LB
authors: Wilson
authors: Michael A
authors: MA
authors: Rosenthal
authors: Saasha
authors: S
authors: Sutera
authors: Alyssa D
authors: AD
authors: Verbalis
authors: Marianne
authors: M
authors: Barton
authors: Sarah
authors: S
authors: Hodgson
authors: James
authors: J
authors: Green
authors: Thyde
authors: T
authors: Dumont-Mathieu
authors: Fred
authors: F
authors: Volkmar
authors: Katarzyna
authors: K
authors: Chawarska
authors: Ami
authors: A
authors: Klin
authors: Deborah
authors: D
authors: Fein
mesh_terms: D001321:Autistic Disorder / Q000175:diagnosis* / Q000453:epidemiology*; D002675:Child, Preschool; D042241:Early Diagnosis; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008403:Mass Screening / Q000379:methods*; D011795:Surveys and Questionnaires