title: 5-HT7 receptor ligands: recent developments and potential therapeutic applications.
abstract: The 5-HT(7) receptors (5-HT(7)Rs) are the most recent classified members of the serotonin family. Characterized in 1993, they belong to the G protein-coupled receptor family. Since their discovery, they have been the subject of intense research due to their widespread distribution in the brain, suggestive of multiple central roles. The focus of this review is to discuss the literature concerning recent advances on 5-HT(7)Rs and their ligands.
authors: Dipartimento di Scienze Farmaceutiche. Facoltà di Farmacia, Università di Catania, Viale A. Doria 6, 95125 Catania, Italy. vpittala@unict.it
authors: Valeria
authors: V
authors: Pittalà
authors: Loredana
authors: L
authors: Salerno
authors: Maria
authors: M
authors: Modica
authors: Maria Angela
authors: MA
authors: Siracusa
authors: Giuseppe
authors: G
authors: Romeo
mesh_terms: D000818:Animals; D006801:Humans; D008024:Ligands; D011985:Receptors, Serotonin / Q000187:drug effects* / Q000378:metabolism; D018490:Serotonin Agents / Q000378:metabolism / Q000494:pharmacology*
chemical_list: D008024:Ligands; D011985:Receptors, Serotonin; D018490:Serotonin Agents; C104425:serotonin 7 receptor