title: [Cervical lymph node metastasis of pyriform sinus carcinoma].
abstract: OBJECTIVE
  To investigate the characteristic of cervical lymph node metastasis of pyriform sinus carcinoma.
  
  
  METHODS
  One hundred and two pyriform sinus carcinoma patients who accepted treatments in the EENT Hospital of Fudan University from 1990 to 2006 were reviewed retrospectively. All of them did not have any treatment and received surgical treatment in our hospital. Stage was made according to the standard of International Union Against Cancer (UICC)in 1997. The distribution of cervical lymph node was confirmed by CT scanning and pathology.
  
  
  RESULTS
  The rates of lymph node metastasis were 16.7% , 59.4%, 70.8% and 63.6% for patients with T1 disease, T2, T3 and T4 (P <0.05), respectively, and 62.7% (64/102) for the whole patients. The bilateral metastasis rate were 2.70% (1/37), 12.5% (6/48) and 18.1% (2/11) for T2, T3 and T1, respectively (P <0.05). The occurrence of cervical lymph node metastasis was 3.87% in the level I , 33.55% in the level II, 30.97% in the level III, 25.16% in the level IV, 5.16% in the level V, 1.29% in the level VI (P <0.05). Fourteen patients with cN0 stage had modified neck dissection and 10 patients had lymph node metastasis (71.4%). The lymph node metastasis of cN0 and cN1 was all in the level II, level III and level IV. And cN2 and cN3 also had some in the level I, level V and level VI.
  
  
  CONCLUSIONS
  T2, T3 and T4 all had high rates for lymph node metastasis while T3, T4 were easier for contralateral metastasis. T3, T4 and contralateral metastasis were easier to surpassing the lymph node envelope. The lymph node metastasis of cN0 and cN1 was all in the level II, level III and level IV. And cN2 and cN3 also had some in the level I, level V and level VI.
authors: Department of Otorhinolaryngology, Otorhinolaryngology Hospital of Fudan University, Shanghai, 200031, China.
authors: Na
authors: N
authors: Shen
authors: Xiuyin
authors: X
authors: Xu
authors: Haitao
authors: H
authors: Wu
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D007012:Hypopharyngeal Neoplasms / Q000473:pathology*; D008198:Lymph Nodes / Q000473:pathology*; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D009333:Neck / Q000473:pathology; D009367:Neoplasm Staging; D056144:Pyriform Sinus / Q000473:pathology; D012189:Retrospective Studies