Differences in treatment and in outcomes between idiopathic and secondary forms of organizing pneumonia.
Organizing pneumonia is a major reparative response of the lung tissue to an acute injury and is a pathological hallmark of an entity called bronchiolitis obliterans organizing pneumonia (BOOP). It can be idiopathic and called cryptogenic organizing pneumonia (COP) or be secondary to various conditions such as infections, drugs, connective tissue disorders, and radiation. Fifty-seven patients with pathologically confirmed BOOP were identified and were classified as having either COP or secondary BOOP on the basis of whether there was an identifiable cause. The two groups were compared for demographic, clinical, laboratory, radiological and treatment variables. Duration of treatment with corticosteroids was longer for patients with COP.
Basarakodu
Krishnamohan R
KR
Department of Medicine, Alegent Health Mercy Hospital, Council Bluffs, IA, USA.
Aronow
Wilbert S
WS
Nair
Chandra K
CK
Lakkireddy
Dhanunjaya
D
Kondur
Ashok
A
Korlakunta
Hema
H
Valasareddi
Sri Laxmi
SL
Lem
Vincent
V
Schuller
Dan
D
D000328:Adult; D000368:Aged; D018549:Cryptogenic Organizing Pneumonia / Q000188:drug therapy* / Q000209:etiology; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use*; D006784:Hospitals, Teaching; D006801:Humans; D008168:Lung / Q000473:pathology; D008297:Male; D008499:Medical Records; D008875:Middle Aged; D011241:Prednisone / Q000627:therapeutic use*; D012189:Retrospective Studies; D013997:Time Factors; D016896:Treatment Outcome
D005938:Glucocorticoids; D011241:Prednisone