[Transposition of autologous cultivated bone marrow cells promotes prevention and treatment of immunodependent complications in cardiosurgical patients].
Coronary artery bypass grafting (CABG) has been made in two groups of patients with chronic heart failure (CHF) with further estimation of the rate of postoperative organic dysfunctions and pyoseptic complications. In group 1 (n = 50) CABG was combined with intracoronary or intramyocardial injection of autologous precultivated for 7-8 days mononuclear cells of the bone marrow (1 x 10(9) cells). In group 2 (n = 479) the intraoperative injection of the above cells was not made. It was found that autologous cultivated mononuclear bone marrow cells prevent organic dysfunction and reduce frequency of infectious-septic complications especially in patients with preoperative focuses of chronic infections.
Temnov
A A
AA
Gabrielian
N I
NI
Nikol'skaia
A O
AO
Savost'ianova
O A
OA
Suskova
V S
VS
Onishchenko
N A
NA
Gureev
S V
SV
Vasil'ev
K N
KN
Sukhachev
A A
AA
Sibiakina
A A
AA
D000328:Adult; D000368:Aged; D001854:Bone Marrow Cells / Q000166:cytology*; D016026:Bone Marrow Transplantation / Q000379:methods*; D006348:Cardiac Surgical Procedures; D006801:Humans; D008875:Middle Aged; D009102:Multiple Organ Failure / Q000453:epidemiology / Q000276:immunology / Q000517:prevention & control; D011183:Postoperative Complications; D018805:Sepsis / Q000453:epidemiology / Q000276:immunology / Q000517:prevention & control; D014182:Transplantation, Autologous; D016896:Treatment Outcome