[Mechanisms of bone calcification].
In bone calcification, hydroxyapatite is crystallized on the type I collagen-based organic matrices. It occurs in the extracellular spaces. Osteoblasts trigger and promote the crystallization by the biological control to the secretion of various matrix proteins or enzymes. The author overviews the mineral and organic environments in calcification areas and the roles of osteoblasts in mineral/organic interaction.
Hoshi
Kazuto
K
The University of Tokyo, Graduate School of Medicine, Department of Cartilage & Bone Regeneration (Fujisoft).
D002113:Calcification, Physiologic / Q000502:physiology*; D003460:Crystallization; D017886:Durapatite / Q000378:metabolism; D006801:Humans; D010006:Osteoblasts / Q000502:physiology
D017886:Durapatite