title: Treatment of iatrogenic femoral pseudoaneurysm by ultrasound-guided compression therapy and thrombin injection.
abstract: Development of an arterial pseudoaneurysm is a common complication following cardiac catheterization. We analyzed data from 6,300 patients who received left heart catheterization at our institution. One day after the procedure, approximately 10% of the patients were examined with duplex sonography. In 204 patients (3.0%), a pseudoaneurysm of the femoral artery was diagnosed. All patients underwent compression therapy. Thereby, 159 of the pseudoaneurysms could be treated successfully. The remaining 45 pseudoaneurysms had a maximal diameter of more than 1.5 cm. Forty-two patients underwent ultrasound and biopsy-line-guided thrombin injection without complications. This strategy resulted in a successful occlusion in 41 cases. Pseudoaneurysms smaller than 2 cm can be treated with compression therapy. Larger pseudoaneurysms can be occluded by thrombin injection using ultrasound guidance. Patients with a pseudoaneurysm with a wide "neck" should be treated surgically, because the risk of an arterial occlusion following thrombin injection cannot be excluded.
authors: Department of Cardiology, University of Heidelberg, Germany. mark.luedde@med.uni -heidelberg.de
authors: Mark
authors: M
authors: Luedde
authors: Ulrike
authors: U
authors: Krumsdorf
authors: Joerg
authors: J
authors: Zehelein
authors: Boris
authors: B
authors: Ivandic
authors: Thomas
authors: T
authors: Dengler
authors: Hugo A
authors: HA
authors: Katus
authors: Christiane
authors: C
authors: Tiefenbacher
mesh_terms: D017541:Aneurysm, False / Q000000981:diagnostic imaging / Q000209:etiology / Q000628:therapy; D006328:Cardiac Catheterization / Q000009:adverse effects*; D005263:Femoral Artery / Q000000981:diagnostic imaging / Q000293:injuries*; D005500:Follow-Up Studies; D006489:Hemostatic Techniques; D006490:Hemostatics / Q000008:administration & dosage*; D006801:Humans; D007049:Iatrogenic Disease; D007269:Injections, Intra-Arterial; D011312:Pressure; D012189:Retrospective Studies; D013917:Thrombin / Q000008:administration & dosage*; D016896:Treatment Outcome; D018616:Ultrasonography, Doppler, Duplex
chemical_list: D006490:Hemostatics; D013917:Thrombin