Self-assembly of beta-cyclodextrin in water. 2. Electron spin resonance.
The interaction of amphipilic spin labels with beta-cyclodextrin was investigated using conventional electron spin resonance (ESR) spectroscopy to explore the aggregation of cyclodextrins in water. Methyl 5-doxylstearate (5-DMS) and stearic acid spin probes (n-DSA), which contain a cyclic nitroxide moiety with unpaired electrons covalently linked to the aliphatic chain carbon in positions 5, 7, 12, and 16, show that different dynamic domains coexist in beta-CD water solutions above 3 mM. The results are consistent with the formation of beta-CD self-assembled structures in water above a critical aggregation concentration and confirm the previous findings that were reported in the part 1 article of this series.
Rossi
Simona
S
Department of Chemistry and CSGI, University of Florence, 50019 Sesto Fiorentino, Italy.
Bonini
Massimo
M
Lo Nostro
Pierandrea
P
Baglioni
Piero
P