title: Augmentation strategies to increase antidepressant tolerability.
abstract: The goal of antidepressant treatment is full remission, but adverse events prevent many patients from reaching and sustaining this goal. Differential diagnosis should be made between antidepressant side effects and adverse events that are related to other causes. Antidepressant side effects may be transient or persistent and may occur early or later in treatment. Pharmacologic and nonpharmacologic strategies can be used to improve the tolerability of antidepressants, resulting in a greater probability of achieving and sustaining remission.
authors: Department of Psychiatry, Rush University Medical Center, Chicago, IL 60612, USA. john_zajecka@rush.edu
authors: John M
authors: JM
authors: Zajecka
mesh_terms: D000928:Antidepressive Agents / Q000009:adverse effects* / Q000627:therapeutic use; D001714:Bipolar Disorder / Q000175:diagnosis; D003865:Major Depressive Disorder / Q000188:drug therapy*; D003937:Diagnosis, Differential; D006801:Humans; D012074:Remission Induction; D012735:Sexual Dysfunction, Physiological / Q000139:chemically induced / Q000517:prevention & control; D019966:Substance-Related Disorders / Q000175:diagnosis
chemical_list: D000928:Antidepressive Agents