title: Comparison of automated assays for the determination of vitamin B12 in serum.
abstract: OBJECTIVE
  To study the agreement of serum cobalamin results obtained with three different widely used analyzers.
  
  
  METHODS
  Comparative measurement of 100 serum samples was performed using the Abbott Architect, the Bayer Centaur, and the Roche Elecsys 2010 analyzer.
  
  
  RESULTS
  Relatively close numeric correlation of the results was found with Pearson's r>0.95 for all three comparisons; however, the mean concentration of the highest reading and the lowest reading method differed by 16%.
  
  
  CONCLUSIONS
  Relatively good agreement of results from three automated serum cobalamin assays was observed.
authors: Institute of Clinical Chemistry, Hospital of the University of Munich, Marchioninistr. 15, D-81377 Munich, Germany. Michael.Vogeser@med.uni-muenchen.de
authors: Michael
authors: M
authors: Vogeser
authors: Stefan
authors: S
authors: Lorenzl
mesh_terms: D019963:Clinical Chemistry Tests / Q000295:instrumentation / Q000379:methods*; D006801:Humans; D015203:Reproducibility of Results; D014805:Vitamin B 12 / Q000097:blood*
chemical_list: D014805:Vitamin B 12