title: Cervical cancer associated with pregnancy: results of a multicenter retrospective Korean study (KGOG-1006).
abstract: OBJECTIVE
  The objective of the study was to analyze the characteristics of cervical cancer associated with pregnancy.
  
  
  METHODS
  Forty patients with cervical cancer associated with pregnancy were retrospectively identified between 1995-2003. Three controls for each case were matched on the basis of age, stage, histology, and date of treatment.
  
  
  RESULTS
  Sampling of cervical cytology after the second trimester was the most common cause of delayed diagnosis. Among 12 patients who delayed treatment for fetal maturity, 2 died of disease. There was no difference in overall survival between pregnant and nonpregnant patients with stage Ib tumors. In contrast to nonpregnant patients, the depth of stromal invasion was not correlated with the incidence of lymph vascular space involvement and lymph node metastasis in pregnant patients.
  
  
  CONCLUSIONS
  Thorough evaluation is warranted before deciding whether to delay treatment until fetal maturity. Pregnancy does not adversely affect the prognosis of early-stage cervical cancer significantly.
authors: Department of Obstetrics and Gynecology, East-West Neo Medical Center, Kyung Hee University, Seoul, Korea.
authors: Jong-Min
authors: JM
authors: Lee
authors: Kwang-Beom
authors: KB
authors: Lee
authors: Young-Tak
authors: YT
authors: Kim
authors: Hee-Sug
authors: HS
authors: Ryu
authors: Young-Tae
authors: YT
authors: Kim
authors: Chi-Heum
authors: CH
authors: Cho
authors: Sung-Eun
authors: SE
authors: Namkoong
authors: Ki-Hun
authors: KH
authors: Lee
authors: Ho-Sun
authors: HS
authors: Choi
authors: Kyung-Tai
authors: KT
authors: Kim
mesh_terms: D000328:Adult; D017677:Age Distribution; D016022:Case-Control Studies; D003131:Combined Modality Therapy; D015897:Comorbidity; D005260:Female; D005865:Gestational Age; D006801:Humans; D015994:Incidence; D007723:Korea / Q000453:epidemiology; D008875:Middle Aged; D009367:Neoplasm Staging; D011181:Postnatal Care / Q000379:methods; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000453:epidemiology* / Q000473:pathology* / Q000628:therapy; D011256:Pregnancy Outcome; D011295:Prenatal Care / Q000379:methods; D011336:Probability; D011379:Prognosis; D012016:Reference Values; D012189:Retrospective Studies; D018570:Risk Assessment; D018709:Statistics, Nonparametric; D016019:Survival Analysis; D002583:Uterine Cervical Neoplasms / Q000453:epidemiology* / Q000473:pathology* / Q000628:therapy