title: Successful treatment of relapsing neuro-Sweet's disease with corticosteroid and dapsone combination therapy.
abstract: Sweet's disease with central nervous system involvement, tentatively named neuro-Sweet's disease, has rarely been reported. Although systemic corticosteroid therapy is highly effective for neurologic symptoms in neuro-Sweet's disease, relapse is common. Here, we describe the case of a 38-year-old Japanese man who presented with relapsing neuro-Sweet's disease that was successfully treated with a combination of corticosteroid and dapsone. Dapsone should be considered as a therapeutic option for neuro-Sweet's disease patients showing relapse.
authors: Department of Neurology, Juntendo University Shizuoka Hospital, 1129 Nagaoka, Izunokuni, Shizuoka 410-2295, Japan.
authors: Jiro
authors: J
authors: Fukae
authors: Kazuyuki
authors: K
authors: Noda
authors: Kenji
authors: K
authors: Fujishima
authors: Ryo
authors: R
authors: Wada
authors: Takashi
authors: T
authors: Yoshiike
authors: Nobutaka
authors: N
authors: Hattori
authors: Yasuyuki
authors: Y
authors: Okuma
mesh_terms: D000284:Administration, Oral; D000328:Adult; D000890:Anti-Infective Agents / Q000008:administration & dosage*; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage*; D001706:Biopsy; D001921:Brain / Q000473:pathology; D003622:Dapsone / Q000008:administration & dosage*; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D004359:Drug Therapy, Combination; D006801:Humans; D007262:Infusions, Intravenous; D008279:Magnetic Resonance Imaging; D008297:Male; D008590:Meningoencephalitis / Q000175:diagnosis / Q000188:drug therapy* / Q000473:pathology; D008775:Methylprednisolone / Q000008:administration & dosage*; D011239:Prednisolone / Q000008:administration & dosage*; D012008:Recurrence; D012867:Skin / Q000473:pathology; D016463:Sweet Syndrome / Q000175:diagnosis / Q000188:drug therapy* / Q000473:pathology
chemical_list: D000890:Anti-Infective Agents; D000893:Anti-Inflammatory Agents; D003622:Dapsone; D011239:Prednisolone; D008775:Methylprednisolone