Statins increase risk of hemorrhagic stroke by inhibition of the PAR-1 receptor.
Serebruany
Victor L
VL
HeartDrug Research Laboratories, Johns Hopkins University, Baltimore, MD, USA. heartdrug@aol.com
Malinin
Alex I
AI
Hennekens
Charles H
CH
D002543:Cerebral Hemorrhage / Q000139:chemically induced* / Q000150:complications / Q000378:metabolism; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000009:adverse effects*; D044463:Receptor, PAR-1 / Q000378:metabolism; D018570:Risk Assessment; D012307:Risk Factors; D020521:Stroke / Q000209:etiology* / Q000378:metabolism; D010975:Platelet Aggregation Inhibitors
D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D044463:Receptor, PAR-1; D010975:Platelet Aggregation Inhibitors