Antimicrobial stewardship.
In response to the global antibiotic resistance crisis, antimicrobial stewardship programs have emerged throughout the United States. Effective programs integrate several strategic methods, including evaluation and feedback regarding the necessity and appropriateness of antimicrobial therapy, staff education, and formulary restrictions. Multidisciplinary teams as well as institutional support are needed to form effective subcommittees to monitor national and local surveillance reports and resistance patterns, and to update antibiograms. Computerized decision support programs have been effective and successful methods of antimicrobial stewardship and can be a powerful tool in stewardship programs. Successful programs have reduced not only institutional resistance rates, but also morbidity, mortality, and cost.
Rybak
Michael J
MJ
Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, Michigan 48201, USA.
D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D001419:Bacteria / Q000187:drug effects; D001424:Bacterial Infections / Q000188:drug therapy; D017046:Cost Savings; D003658:Decision Making, Computer-Assisted; D024881:Drug Resistance, Bacterial; D005572:Formularies, Hospital as Topic; D006761:Hospitals; D006801:Humans; D008826:Microbial Sensitivity Tests; D010348:Patient Care Team; D017410:Practice Guidelines as Topic; D010818:Practice Patterns, Physicians'; D014481:United States
D000900:Anti-Bacterial Agents