[Myelodysplastic syndromes associated with acquired hemoglobin H disease].
OBJECTIVE
To report 7 cases of acquired hemoglobin H in myelodysplastic syndromes.
Clinical materials of the 7 cases were retrospectively presented. Clinical features of the similar cases in literatures were reviewed. The criteria for diagnosis of this entity by Steensma and its pathogenesis were discussed.


CONCLUSIONS
This entity is a new subtype of MDS with unique clinical features and pathogenesis, and might be a proper model in the study of MDS transformation.
Qi
Jun-yuan
JY
Institute of Hematology & Blood Diseases Hospital, CAMS & PUMC, Tianjin 300020, China.
Zhang
Feng-kui
FK
Zhou
Ze-ping
ZP
Zhao
Yu-ping
YP
Yang
Ren-chi
RC
Qian
Lin-sheng
LS
Zheng
Yi-zhou
YZ
D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009190:Myelodysplastic Syndromes / Q000150:complications*; D017085:alpha-Thalassemia / Q000150:complications*