title: SNP mapping of QTL affecting growth and fatness on chicken GGA1.
abstract: An F2 chicken population was established from a crossbreeding between a Xinghua line and a White Recessive Rock line. A total of 502 F2 chickens in 17 full-sib families from six hatches was obtained, and phenotypic data of 488 individuals were available for analysis. A total of 46 SNP on GGA1 was initially selected based on the average physical distance using the dbSNP database of NCBI. After the polymorphism levels in all F0 individuals (26 individuals) and part of the F1 individuals (22 individuals) were verified, 30 informative SNP were potentially available to genotype all F2 individuals. The linkage map was constructed using Cri-Map. Interval mapping QTL analyses were carried out. QTL for body weight (BW) of 35 d and 42 d, 49 d and 70 d were identified on GGA1 at 351-353 cM and 360 cM, respectively. QTL for abdominal fat weight was on GGA1 at 205 cM, and for abdominal fat rate at 221 cM. Two novel QTL for fat thickness under skin and fat width were detected at 265 cM and 72 cM, respectively.
authors: Department of Animal Genetics, Breeding and Reproduction, College of Animal Science, South China Agricultural University, Guangzhou 510642, Guangdong, China.
authors: Yousheng
authors: Y
authors: Rao
authors: Xu
authors: X
authors: Shen
authors: Mengna
authors: M
authors: Xia
authors: Chenglong
authors: C
authors: Luo
authors: Qinghua
authors: Q
authors: Nie
authors: Dexiang
authors: D
authors: Zhang
authors: Xiquan
authors: X
authors: Zhang
mesh_terms: D020727:ADP-Ribosylation Factors / Q000235:genetics*; D033942:Adaptor Proteins, Vesicular Transport / Q000235:genetics*; D050154:Adiposity / Q000235:genetics*; D000818:Animals; D001483:Base Sequence; D002645:Chickens / Q000033:anatomy & histology / Q000235:genetics* / Q000254:growth & development*; D016001:Confidence Intervals; D017931:DNA Primers / Q000235:genetics; D005260:Female; D008297:Male; D010641:Phenotype; D020641:Polymorphism, Single Nucleotide; D040641:Quantitative Trait Loci
chemical_list: D033942:Adaptor Proteins, Vesicular Transport; D017931:DNA Primers; C407306:GGA adaptor proteins; D020727:ADP-Ribosylation Factors