Some recent advances in the synthesis of polycyclic imidazole-containing marine natural products.
This Highlight describes some of the recent synthetic work on imidazole-containing alkaloids isolated from marine sponges. Target molecules have been chosen which demonstrate synthetic strategies leading towards metabolites containing intact imidazole moieties as well as systems bearing modified imidazole rings.
Weinreb
Steven M
SM
Department of Chemistry, The Pennsylvania State University, University Park, PA 16802, USA. smw@chem.psu.edu
D000470:Alkaloids / Q000138:chemical synthesis* / Q000737:chemistry; D000818:Animals; D001688:Biological Products / Q000138:chemical synthesis* / Q000737:chemistry; D007093:Imidazoles / Q000138:chemical synthesis* / Q000737:chemistry*; D008386:Marine Biology; D015394:Molecular Structure; D011161:Porifera / Q000737:chemistry*
D000470:Alkaloids; D001688:Biological Products; D007093:Imidazoles