title: Dark-blood MRI of the thoracic aorta with 3D diffusion-prepared steady-state free precession: initial clinical evaluation.
abstract: OBJECTIVE
  The purpose of this study was to compare the performance of 3D diffusion-prepared balanced steady-state free precession (SSFP) imaging with that of 3D contrast-enhanced MR angiography in evaluation of the thoracic aorta.
  
  
  METHODS
  Twenty-one patients with indications for contrast-enhanced MR angiography and diffusion-prepared SSFP of the thoracic aorta were involved in this retrospective chart review study conducted with 1.5-T MRI. Two observers scored the quality of the contrast-enhanced MR angiographic and diffusion-prepared SSFP images on the basis of depicting the thoracic aorta. Image quality scores and diametric measurements of the aorta from both image sets were compared.
  
  
  RESULTS
  Diametric measurements of the thoracic aorta showed a strong linear association (r = 0.971, p < 0.0001; regression line indifferent from line of equality, p < 0.05). The aortic root was better visualized with contrast-enhanced MR angiography (image quality score, 3.6 +/- 0.9 vs 3.0 +/- 0.8 of 5; p < 0.05); however, the aortic wall was better visualized with diffusion-prepared SSFP (image quality score, 4.4 +/- 0.6 vs 1.9 +/- 0.3 of 5; p < 0.0001).
  
  
  CONCLUSIONS
  Three-dimensional diffusion-prepared SSFP yields better image quality than 3D contrast-enhanced MR angiography in evaluation of the thoracic aortic wall and appears to be a useful adjunct to 3D contrast-enhanced MR angiography for assessing aortic abnormalities before administration of a contrast agent.
authors: Department of Radiology, Northwestern University Feinberg School of Medicine, 448 E Ontario St., Suite 700, Chicago, IL 60611, USA. i-koktzoglou@northwestern.edu
authors: Ioannis
authors: I
authors: Koktzoglou
authors: Anish
authors: A
authors: Kirpalani
authors: Timothy J
authors: TJ
authors: Carroll
authors: Debiao
authors: D
authors: Li
authors: James C
authors: JC
authors: Carr
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001013:Aorta, Thoracic; D001018:Aortic Diseases / Q000175:diagnosis*; D038524:Diffusion Magnetic Resonance Imaging / Q000379:methods*; D005260:Female; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D021621:Imaging, Three-Dimensional / Q000379:methods*; D008297:Male; D008875:Middle Aged; D010865:Pilot Projects; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity