Pregnane glycosides from Solanum nigrum.
Two new pregnane saponins, solanigroside A (1) and solanigroside B (2), along with two known compounds (3 and 4), were isolated from 60% ethanolic extract of the dried herb of Solanum nigrum L. The structures of 1 and 2 were elucidated as 5alpha-pregn-16-en-3beta-ol-20-one 3-O-beta-D-xylopyranosyl-(1 --> 3)-O-[alpha-L-arabinopyranosyl-(1 --> 2)]-O-beta-D-glucopyranosyl-(1 --> 4)-O-[alpha-L-rhamnopyranosyl-(1 --> 2)]-O-beta-D-galactopyranoside (1) and 5alpha-pregn-16-en-3beta-ol-20-one 3-O-beta-D-glucopyranosyl-(1 --> 2)-O-[beta-D-glucopyranosyl-(1 --> 3)]-O-beta-D-glucopyranosyl-(1 --> 4)-O-beta-D-galactopyranoside (2), respectively, on the basis of extensive spectroscopic analysis as well as comparison with reported spectroscopic data of related compounds. This paper deals with the isolation and structural characterisation of pregnane glycosides from S. nigrum L.
Zhou
Xin-Lan
XL
Department of Natural Products Chemistry, Shenyang Pharmaceutical University, Shenyang, China.
He
Xiang-Jing
XJ
Zhou
Guang-Xiong
GX
Ye
Wen-Cai
WC
Yao
Xin-Sheng
XS
D002236:Carbohydrate Conformation; D002240:Carbohydrate Sequence; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification*; D009682:Magnetic Resonance Spectroscopy; D008969:Molecular Sequence Data; D011278:Pregnanes / Q000737:chemistry / Q000302:isolation & purification*; D032322:Solanum / Q000737:chemistry*; D021241:Spectrometry, Mass, Electrospray Ionization
D006027:Glycosides; D011278:Pregnanes