The plausibility of Helicobacter pylori-related infertility in Japan.
The aim of the present study was to confirm the seropositive rate of Helicobacter pylori to which antibodies cross-react with spermatozoon flagella in patients with infertility. Of the 204 patients in whom the anti-H. pylori IgG antibody in serum and follicular fluids were measured, 45 (22.1%) were seropositive for H. pylori and the seropositive percentage of infertile patients without any possible cause was higher than that of patients with one or more known infertility factors [8 of 21 patients (38.3%) vs. 37 of 183 patients (20.2%), respectively], which suggests a new concept: H. pylori-related infertility.
Kurotsuchi
Shozo
S
Department of Obstetrics and Gynecology and Department of Maternal and Perinatal Medicine, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Ando
Hisao
H
Iwase
Akira
A
Ishida
Yoshiko
Y
Hamajima
Nobuyuki
N
Kikkawa
Fumitaka
F
D000328:Adult; D015897:Comorbidity; D005240:Feasibility Studies; D005260:Female; D016481:Helicobacter Infections / Q000453:epidemiology*; D016480:Helicobacter pylori; D006801:Humans; D015994:Incidence; D007247:Infertility, Female / Q000453:epidemiology*; D007564:Japan / Q000453:epidemiology; D018570:Risk Assessment / Q000379:methods*; D012307:Risk Factors