Purpura fulminans in a child secondary to Panton-Valentine leukocidin-producing Staphylococcus aureus.
A case of purpura fulminans (PF) in a child secondary to infection with meticillin-sensitive Staphylococcus aureus (MSSA) encoding the Panton-Valentine leukocidin (PVL) toxin genes is presented. Occasional cases of PF have been documented secondary to S. aureus infection in adults, but, to the authors' knowledge, not in children. Here the first UK case of MSSA-PVL leading to PF is presented.
Hussain
Abid
A
Department of Clinical Microbiology, Leicester Royal Infirmary, University Hospitals of Leicester NHS Trust, Leicester LE1 5WW, UK.
Robinson
Gisela
G
Department of Child Health, Leicester Royal Infirmary, University Hospitals of Leicester NHS Trust, Leicester LE1 5WW, UK.
Malkin
Joanne
J
Department of Clinical Microbiology, Leicester Royal Infirmary, University Hospitals of Leicester NHS Trust, Leicester LE1 5WW, UK.
Duthie
Mark
M
Department of Child Health, Leicester Royal Infirmary, University Hospitals of Leicester NHS Trust, Leicester LE1 5WW, UK.
Kearns
Angela
A
Staphylococcal Reference Laboratory, Laboratory of Healthcare Associated Infection, Health Protection Agency, Colindale, London NW9 5EQ, UK.
Perera
Nelun
N
Department of Clinical Microbiology, Leicester Royal Infirmary, University Hospitals of Leicester NHS Trust, Leicester LE1 5WW, UK.
D001427:Bacterial Toxins / Q000096:biosynthesis*; D005098:Exotoxins / Q000096:biosynthesis*; D005260:Female; D006801:Humans; D011695:IgA Vasculitis / Q000382:microbiology*; D007223:Infant; D007956:Leukocidins / Q000096:biosynthesis*; D013203:Staphylococcal Infections / Q000150:complications* / Q000382:microbiology*; D013211:Staphylococcus aureus / Q000302:isolation & purification*; D006113:United Kingdom
D001427:Bacterial Toxins; D005098:Exotoxins; D007956:Leukocidins; C078284:Panton-Valentine leukocidin