title: Dynamically configurable biomolecular nanoarrays.
abstract: Nanoarrays of distinct DNA and protein biomolecules were fabricated by electrochemically controlling their assembly/release from Au nanoelectrodes on a chip. The surface density, ratio, and activity of the biomolecules assembled on each nanoelectrode in the array can be configured quantitatively and temporally by adjusting the electrochemical potential applied on the nanoelectrode. The dynamically configurable biomolecular nanoarray can potentially activate combinatorial interactions with microbiosystems under the control of an electronic circuit for biological and medical applications.
authors: Department of Mechanical and Aerospace Engineering, California NanoSystems Institute, University of California, Los Angeles, California 90095, USA. huangsuxian@ucla.edu
authors: Suxian
authors: S
authors: Huang
authors: Eric
authors: E
authors: Schopf
authors: Yong
authors: Y
authors: Chen
mesh_terms: D004563:Electrochemistry / Q000295:instrumentation* / Q000379:methods; D004867:Equipment Design; D019544:Equipment Failure Analysis; D008839:Microelectrodes; D036103:Nanotechnology / Q000295:instrumentation* / Q000379:methods; D020411:Oligonucleotide Array Sequence Analysis / Q000295:instrumentation* / Q000379:methods