title: [Manifestation of congenital rubella syndrome: clinical and epidemiologic aspects].
abstract: BACKGROUND
  Congenital rubella syndrome is an ensemble of congenital malformations which results from a primary viral infection in non-immunised pregnant women. The main ophthalmologic manifestation is cataract. It involves at the same time visual and vital prognosis and can be responsible for multiple handicaps.
  
  
  METHODS
  We did a retrospective study of 16 infants (32 eyes) having undergone congenital cataract surgery compatible with congenital rubella syndrome in the Casablanca paediatric ophthalmology department between January 2001 and December 2005. All the patients underwent a complete ophthalmologic examination, otorhinolaryngologic, cardiovascular and neurological examinations, and paraclinic explorations.
  
  
  RESULTS
  The results were compared with those reported in the literature. In our series, 25 eyes (78.12%) had a cataract of which 56% were nuclear, 13 eyes (40.62%) had microphthalmia. One case each of corneal dystrophy and iris coloboma were described. Congenital glaucoma was found in only one case. Pigmentary retinopathy was found in 12 eyes (37.5%). Seven patients (43.75%) had associated cardiac anomalies, 6 (37.5%) deafness, 5 (31.25%) psychomotor delay and 2 (12.5%) facial dysmorphy.
  
  
  CONCLUSIONS
  Considering the permanent disabilities caused by congenital rubella syndrome, care should be taken with the follow-up of the pregnancies and an immunization program should be implemented for good control of the circulation of the virus.
authors: Service d'Ophtalmologie pédiatrique, Hôpital 20 Août 1953, CHU Ibn Rochd, Casablanca, Maroc. ldiaa1@caramail.com
authors: D
authors: D
authors: Lahbil
authors: L
authors: L
authors: Souldi
authors: L
authors: L
authors: Rais
authors: H
authors: H
authors: Lamari
authors: A
authors: A
authors: El Kettani
authors: K
authors: K
authors: Zaghloul
mesh_terms: D000015:Abnormalities, Multiple / Q000175:diagnosis*; D002386:Cataract / Q000151:congenital*; D002387:Cataract Extraction; D003638:Deafness / Q000175:diagnosis; D005901:Glaucoma / Q000151:congenital; D006330:Heart Defects, Congenital / Q000175:diagnosis*; D006801:Humans; D007223:Infant; D012174:Retinitis Pigmentosa / Q000175:diagnosis; D012189:Retrospective Studies; D012410:Rubella Syndrome, Congenital / Q000175:diagnosis* / Q000601:surgery