Natural history of sub-retinal triamcinolone acetonide deposition after triamcinolone-assisted vitrectomy.
OBJECTIVE
To describe the natural course of subretinal triamcinolone acetonide (TA) deposition after a TA-assisted vitrectomy for retinal detachment.


METHODS
Observational case series.


RESULTS
TA deposition was observed between the neurosensory retina and retinal pigment epithelium in the macular area at the conclusion of vitreoretinal surgery in three patients with retinal detachment. On follow up, TA granules gradually decreased over the next 2 weeks and resolved completely by 3 weeks. Two months after the operation, the retina was observed to be successfully attached and no ophthalmoscopic or functional damage was observed.


CONCLUSIONS
As no apparent clinically detectable adverse effect was found in the three cases that demonstrated subretinal deposition of TA we opine that active surgical maneuvers to remove the same are not warranted during surgery.
Sampangi
Raju
R
Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, 110029, New Delhi, India. venkyprao@yahoo.com
Venkatesh
Pradeep
P
Garg
Sat Pal
SP
D000293:Adolescent; D000328:Adult; D002675:Child, Preschool; D005500:Follow-Up Studies; D005938:Glucocorticoids / Q000009:adverse effects*; D015745:Granuloma, Foreign-Body / Q000209:etiology*; D006801:Humans; D008297:Male; D010857:Pigment Epithelium of Eye / Q000601:surgery; D012163:Retinal Detachment / Q000601:surgery; D012164:Retinal Diseases / Q000209:etiology*; D014222:Triamcinolone Acetonide / Q000009:adverse effects*; D014821:Vitrectomy
D005938:Glucocorticoids; D014222:Triamcinolone Acetonide