title: [Complicated skin and soft tissue infections].
abstract: Skin and soft tissue infections are common diseases. The spectrum ranges from slight furuncles to severe necrotizing soft tissue infections. Grampositive bacteria account for 70-80 % of cases as causative organisms. Diagnostics include rapid evaluation of locally limited or diffuse spreading extent of the disease. In complicated skin and soft tissue infections, surgical intervention with debridement and necronectomy is indicated. Necrotizing skin and soft tissue infections call for programmed redebridement. If systemic signs of inflammation are present (fever > 38 degrees C, leukocytosis, CRP elevation) or significant comorbidity exists, application of antibiotics is indicated. The prognosis in operatively treated patients is dependent on the time of surgical intervention.
authors: Universitätsklinikum Schleswig-Holstein, Campus Lübeck, Klinik für Chirurgie, Lübeck, Germany. peter.kujath@chirurgie.uni-luebeck.de
authors: P
authors: P
authors: Kujath
authors: C
authors: C
authors: Eckmann
authors: R
authors: R
authors: Bouchard
authors: H
authors: H
authors: Esnaashari
mesh_terms: D000038:Abscess / Q000175:diagnosis / Q000401:mortality / Q000601:surgery; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001424:Bacterial Infections / Q000175:diagnosis* / Q000401:mortality / Q000601:surgery; D002097:C-Reactive Protein / Q000378:metabolism; D003131:Combined Modality Therapy; D003422:Critical Care; D003646:Debridement; D004886:Erysipelas / Q000175:diagnosis / Q000401:mortality / Q000601:surgery; D019115:Fasciitis, Necrotizing / Q000175:diagnosis / Q000401:mortality / Q000601:surgery; D005738:Gas Gangrene / Q000175:diagnosis / Q000401:mortality / Q000601:surgery; D006801:Humans; D006931:Hyperbaric Oxygenation; D007958:Leukocyte Count; D016106:Methicillin Resistance; D009894:Opportunistic Infections / Q000175:diagnosis / Q000401:mortality / Q000601:surgery; D011379:Prognosis; D017192:Skin Diseases, Bacterial / Q000175:diagnosis / Q000601:surgery*; D018461:Soft Tissue Infections / Q000175:diagnosis* / Q000401:mortality / Q000601:surgery; D013203:Staphylococcal Infections / Q000175:diagnosis / Q000401:mortality / Q000601:surgery; D013290:Streptococcal Infections / Q000175:diagnosis / Q000401:mortality / Q000601:surgery; D013297:Streptococcus pyogenes; D015996:Survival Rate
chemical_list: D000900:Anti-Bacterial Agents; D002097:C-Reactive Protein