[New information for thoracic surgeons on the pathogenesis of acute exacerbation of interstitial pneumonias].
For the thoracic surgeons, the difficulty in the treatment of patients with interstitial pneumonias may exist in the frequent onset of acute exacerbation after thoracic surgery for lung resection or lung biopsy. The pathogenesis of acute exacerbation is dependent on the remodeling of secondary lobules by fibrosis which induces alveolar-capillary lesions and disruption of superficial lymphatics in these interstitial pneumonias. The understanding of this new pathogenesis of the onset of acute exacerbation of interstitial pneumonias may enable us to prevent and treat this refractory status effectively.
Ebina
Masahito
M
Respiratory Oncology and Molecular Medicine, Institute of Development, Aging and Cancer, Tohoku University, Sendai, Japan.
D006801:Humans; D019451:Information Management; D017563:Lung Diseases, Interstitial / Q000209:etiology* / Q000473:pathology / Q000517:prevention & control*; D011013:Pneumonectomy; D011658:Pulmonary Fibrosis / Q000473:pathology; D013903:Thoracic Surgery; D000078329:Workforce