Suction clearance and 2% topical miconazole versus the same combination with acidic drops in the treatment of otomycosis.
From April 2003 to September 2004, 59 ears from 55 patients received suction clearance and topical miconazole 2% (regimen 1) and in September 2004 to December 2005, 64 ears from 58 patients received the same combinations plus acidic drops [acetic acid 3% (v/ v) in 97% ethanol]. The mean age of patients treated with regimen 1 was 35.76+/-16 years and in regimen 2 was 37.98+/-15 years. Aspergilus sp and Candida sp were seen in 35 (59.3%) and 24 (40.7%) cases treated with regimen 1 and in 43 (67.2%) and 21 (32.8%) cases treated in regimen 2, respectively. Relapse occurred in 2 (3.4%) ears treated with regimen 1, but none in cases treated with regimen 2 (p=0.228). The findings reveal that there were no statistically significant differences between the two regimens and both may be used for the treatment of otomycosis.
Kiakojuri
Kayvan
K
Department of Otolaryngology, Shahid Beheshti Teaching Hospital, Babol Medical University, Babol, Iran. kia_ko13358@yahoo.com
Roushan
Mohammad Reza Hasanjani
MR
Sepidgar
Seyed Ali Asghar
SA
D000328:Adult; D000891:Anti-Infective Agents, Local / Q000494:pharmacology / Q000627:therapeutic use*; D000935:Antifungal Agents / Q000494:pharmacology / Q000627:therapeutic use*; D005260:Female; D005658:Fungi / Q000145:classification / Q000187:drug effects* / Q000302:isolation & purification; D006801:Humans; D007492:Iran; D008297:Male; D008825:Miconazole / Q000494:pharmacology / Q000627:therapeutic use*; D008875:Middle Aged; D009181:Mycoses / Q000175:diagnosis / Q000188:drug therapy*; D010031:Otitis / Q000188:drug therapy* / Q000382:microbiology; D013396:Suction; D016896:Treatment Outcome
D000891:Anti-Infective Agents, Local; D000935:Antifungal Agents; D008825:Miconazole