Neuroleptic malignant syndrome resulting from a complex drug-drug interaction: "I don't see 'em!".
Preskorn
Sheldon H
SH
Department of Psychiatry, University of Kansas School of Medicine-Wichita, Kansas, USA.
D001590:Benztropine / Q000009:adverse effects / Q000493:pharmacokinetics / Q000494:pharmacology; D001714:Bipolar Disorder / Q000188:drug therapy; D065690:Cytochrome P-450 CYP2D6 Inhibitors; D004347:Drug Interactions; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D018020:Lithium Compounds / Q000009:adverse effects / Q000493:pharmacokinetics / Q000494:pharmacology; D008875:Middle Aged; D009459:Neuroleptic Malignant Syndrome / Q000209:etiology*; D017374:Paroxetine / Q000009:adverse effects / Q000493:pharmacokinetics / Q000494:pharmacology; D010546:Perphenazine / Q000009:adverse effects / Q000493:pharmacokinetics / Q000494:pharmacology; D011619:Psychotropic Drugs / Q000009:adverse effects / Q000493:pharmacokinetics* / Q000494:pharmacology*; D014196:Trazodone / Q000009:adverse effects / Q000493:pharmacokinetics / Q000494:pharmacology
D065690:Cytochrome P-450 CYP2D6 Inhibitors; D018020:Lithium Compounds; D011619:Psychotropic Drugs; D001590:Benztropine; D017374:Paroxetine; D010546:Perphenazine; D014196:Trazodone