Progress in the evaluation of transgenic fish for possible ecological risk and its containment strategies.
Genetically improved transgenic fish possess many beneficial economic traits; however, the commercial aquaculture of transgenic fish has not been performed till date. One of the major reasons for this is the possible ecological risk associated with the escape or release of the transgenic fish. Using a growth hormone transgenic fish with rapid growth characteristics as a subject, this paper analyzes the following: the essence of the potential ecological risks posed by transgenic fish; ecological risk in the current situation due to transgenic fish via one-factor phenotypic and fitness analysis, and mathematical model deduction. Then, it expounds new ideas and the latest findings using an artificially simulated ecosystem for the evaluation of the ecological risks posed by transgenic fish. Further, the study comments on the strategies and principles of controlling these ecological risks by using a triploid approach. Based on these results, we propose that ecological risk evaluation and prevention strategies are indispensable important components and should be accompanied with breeding research in order to provide enlightments for transgenic fish breeding, evaluation of the ecological risks posed by transgenic fish, and development of containment strategies against the risks.
Hu
Wei
W
State Key Laboratory of Freshwater Ecology and Biotechnology, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan 430072, China.
Wang
YaPing
Y
Zhu
ZuoYan
Z
D000818:Animals; D030801:Animals, Genetically Modified; D017756:Aquaculture; D003264:Containment of Biohazards; D004463:Ecology; D017753:Ecosystem; D004777:Environment; D004784:Environmental Monitoring / Q000379:methods; D005399:Fishes; D005506:Food Contamination / Q000032:analysis*; D005818:Genetic Engineering / Q000379:methods / Q000639:trends; D005838:Genotype; D013006:Growth Hormone / Q000235:genetics / Q000502:physiology; D008962:Models, Theoretical; D010641:Phenotype; D011003:Ploidies; D018570:Risk Assessment
D013006:Growth Hormone