title: SkinEthic Laboratories, a company devoted to develop and produce in vitro alternative methods to animal use.
abstract: SkinEthic Laboratories is a France-based biotechnology company recognised as the world leader in tissue engineering. SkinEthic is devoted to develop and produce reliable and robust in vitro alternative methods to animal use in cosmetic, chemical and pharmaceutical industries. SkinEthic models provide relevant tools for efficacy and safety screening tests in order to support an integrated decision-making during research and development phases. Some screening tests are referenced and validated as alternatives to animal use (Episkin), others are in the process of validation under ECVAM and OECD guidelines. SkinEthic laboratories provide a unique and joined experience of more than 20 years from Episkin SNC and SkinEthic SA. Their unique cell culture process allows in vitro reconstructed human tissues with well characterized histology, functionality and ultrastructure features to be mass produced. Our product line includes skin models: a reconstructed human epidermis with a collagen layer, Episkin, reconstructed human epidermis without or with melanocytes (with a tanning degree from phototype II to VI) and a reconstructed human epithelium, i.e. cornea, and other mucosa, i.e. oral, gingival, oesophageal and vaginal. Our philosophy is based on 3 main commitments: to support our customers by providing robust and reliable models, to ensure training and education in using validated protocols, allowing a large array of raw materials, active ingredients and finished products in solid, liquid, powder, cream or gel form to be screened, and, to provide a dedicated service to our partners.
authors: SkinEthic Laboratories, Nice, France. adebrugerolle@skinethic.com
authors: Anne
authors: A
authors: de Brugerolle
mesh_terms: D000826:Animal Testing Alternatives / Q000941:ethics* / Q000379:methods*; D000818:Animals; D004817:Epidermis / Q000033:anatomy & histology; D032984:Ethics, Research; D006801:Humans; D007091:Image Processing, Computer-Assisted; D012867:Skin / Q000166:cytology