title: Cranio-spinal subdural empyema due to S. intermedius: a case report.
abstract: OBJECTIVE
  Subdural empyema represents a loculated infection between the dura and the arachnoid. It has been described either intracranially or in the spinal canal, the latter localization being quite rare. While treatment guidelines for a single (either brain or spinal) localization of a subdural empyema are more or less established, its management when a massive involvement of CNS is evident represents a challenge.
  
  
  METHODS
  The authors describe a unique case of a 65-year-old woman having a massive involvement of the entire CNS with multiple localizations, both intracranial and spinal. Early diagnosis was obtained through brain CT scans followed by cranio-spinal contrast enhanced MRI scans. Patient was treated with external ventricular drainage and suboccipital craniectomy, while on antibiotic therapy.
  
  
  RESULTS
  Patient's neurological condition gradually improved. By the end of the eighth hospital week, she was discharged without any neurological deficit.
  
  
  CONCLUSIONS
  Spinal subdural empyema and brain subdural empyema are not always, as in our case, two different entities. Prompt diagnosis and treatment constitute the major variables affecting outcome.
authors: Institute of Neurosurgery, Catholic University School of Medicine, Rome, Italy.
authors: Angelo
authors: A
authors: Pompucci
authors: Pasquale
authors: P
authors: De Bonis
authors: Giovanni
authors: G
authors: Sabatino
authors: Giovanni
authors: G
authors: Federico
authors: Massimo
authors: M
authors: Moschini
authors: Carmelo
authors: C
authors: Anile
authors: Annunziato
authors: A
authors: Mangiola
mesh_terms: D000368:Aged; D000890:Anti-Infective Agents / Q000627:therapeutic use; D003131:Combined Modality Therapy; D003937:Diagnosis, Differential; D013354:Empyema, Subdural / Q000175:diagnosis* / Q000382:microbiology* / Q000628:therapy; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D013290:Streptococcal Infections / Q000175:diagnosis* / Q000382:microbiology / Q000628:therapy; D034367:Streptococcus intermedius / Q000302:isolation & purification*; D014057:Tomography, X-Ray Computed
chemical_list: D000890:Anti-Infective Agents