title: [Relationship between genetic diversity of chromosome 6 determined by microsatellite markers and litter size in Hu sheep].
abstract: Genetic diversity and relationship with litter size were analyzed in Hu sheep using 6 microsatellite markers LSCV043, BMS2508, GC101, 300U, Bulge5, and 471U, which were closely linked to FecB gene. Thirty-four alleles and 53 genotypes were detected at 6 microsatellite loci, which were all polymorphic. Three markers LSCV043, BMS2508 and 300 U were highly polymorphic loci. The polymorphism information content (PIC) were 0.6674, 0.6035, and 0.5615, respectively. The total mean of litter size of genotype LSCV043 107 bp/123 bp was significantly higher than that of genotype 110 bp/123 bp. The litter size of the first lambing for genotypes BMS2508 154 bp/154 bp, 154 bp/170 bp and 154 bp/200 bp were significantly higher than that of genotype 170 bp/170 bp (P<0.05). Furthermore, total litter size for BMS2508 170 bp/170 bp was the lowest in all the genotypes within this locus (P<0.05). No significant difference was detected in other genotypes.
authors: College of Life Sciences, China Jiliang University, Hangzhou 310018, China. jlguanfeng@yahoo.com.cn
authors: Feng
authors: F
authors: Guan
authors: Guo-Qing
authors: GQ
authors: Shi
authors: Jun-Tao
authors: JT
authors: Ai
authors: Shou-Ren
authors: SR
authors: Liu
authors: Li-Guo
authors: LG
authors: Yang
mesh_terms: D000483:Alleles; D000818:Animals; D033481:Chromosomes, Mammalian / Q000235:genetics*; D005787:Gene Frequency; D014644:Genetic Variation; D005838:Genotype; D008098:Litter Size / Q000235:genetics*; D018895:Microsatellite Repeats / Q000235:genetics*; D016133:Polymerase Chain Reaction; D011110:Polymorphism, Genetic; D012756:Sheep / Q000235:genetics*