[Influence of the characteristics of lipids on the regulation of biochemical processes in animal liver and blood].
It has been established experimentally that the character and the scale of interrelations between various parameters of the phospholipid composition and their group-average values depend significantly on the characteristics of lipids (the antioxidative activity, quantity of peroxides, and antiperoxide activity) of animal liver and blood erythrocytes. It was shown that a single injection of low-toxicity Tween 80 and acetone at low doses modifies the intensity of lipid peroxidation in the liver and changes the physicochemical properties of lipids, and the interrelations between the parameters that are coordinated in norm, thereby causing the disturbance of biochemical functions of the liver.
Kozlov
M V
MV
Kushnireva
E V
EV
Urnysheva
V V
VV
Taran
Iu P
IuP
Shishkina
L N
LN
D000096:Acetone / Q000494:pharmacology*; D000818:Animals; D004912:Erythrocytes / Q000378:metabolism*; D005079:Excipients / Q000494:pharmacology*; D005260:Female; D015227:Lipid Peroxidation / Q000187:drug effects*; D008055:Lipids / Q000097:blood*; D008099:Liver / Q000378:metabolism*; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D016877:Oxidants / Q000097:blood; D010545:Peroxides / Q000097:blood; D011136:Polysorbates / Q000494:pharmacology*; D051381:Rats; D012997:Solvents / Q000494:pharmacology*
D005079:Excipients; D008055:Lipids; D016877:Oxidants; D010545:Peroxides; D011136:Polysorbates; D012997:Solvents; D000096:Acetone