Poly (3-(3-pyridyl) acrylic acid) modified glassy carbon electrode for simultaneous determination of dopamine, ascorbic acid and uric acid.
Trans-3-(3-pyridyl) acrylic acid (PAA) was deposited on glassy carbon electrode (GCE) by electropolymerization in pH 7.0 phosphate buffer solution (PBS). The poly (3-(3-pyridyl) acrylic acid) (PPAA) film modified glassy carbon electrode shows an excellent electrochemical response for dopamine (DA), ascorbic acid (AA) and uric acid (UA). The cyclic voltammetry oxidation peaks for DA and AA, DA and UA, AA and UA are separated by 150 mV, 130 mV and 280 mV, respectively. This permits the simultaneous determination of AA, DA and UA. The interference of AA with the determination of DA could be eliminated because of the electrostatic interaction between DA cations and the negatively charged PPAA film at pH 7.0. The anodic peak currents of DA, AA and UA increase linearly with concentration in the range of 1-40 micromol L(-1), 10-400 micromol L(-1) and 1.6-80 micromol L(-1), respectively, with a correlation coefficient (r) always higher than 0.998. The detection limit is 0.06 micromol L(-1), 0.8 micromol L(-1) and 1.1 micromol L(-1) for DA, AA and UA, respectively.
Zhang
Yuzhong
Y
College of Chemistry and Materials Science, Anhui Key Laboratory of Functional Molecular Solids, Anhui Normal University, Wuhu 241000, P.R. China. zhangyz65@hotmail.com
Su
Shao
S
Pan
Yan
Y
Zhang
Liping
L
Cai
Yuejuan
Y
D000180:Acrylic Resins / Q000737:chemistry*; D001205:Ascorbic Acid / Q000032:analysis*; D002021:Buffers; D002244:Carbon / Q000737:chemistry; D004298:Dopamine / Q000032:analysis*; D004563:Electrochemistry / Q000295:instrumentation / Q000379:methods*; D004566:Electrodes; D006863:Hydrogen-Ion Concentration; D010084:Oxidation-Reduction; D011108:Polymers / Q000737:chemistry; D015203:Reproducibility of Results; D014527:Uric Acid / Q000032:analysis*
D000180:Acrylic Resins; D002021:Buffers; D011108:Polymers; C524877:poly(3-(3-pyridyl)acrylic acid); D014527:Uric Acid; D002244:Carbon; D001205:Ascorbic Acid; D004298:Dopamine