title: [Effects of Porphyromonas gingivalis lipopolysaccharide on collagen phagocytosis by human periodontal ligament fibroblasts].
abstract: OBJECTIVE
  To investigate the effects of Porphyromonas gingivalis (P. gingivalis) lipopolysaccharide (LPS) on collagen phagocytosis of human periodontal ligament fibroblasts (hPDLF).
  
  
  METHODS
  Fluorescence localization and flow cytometry was used to test the collagen phygocytosis of hPDLF stimulated by the various concentration of LPS for 48 hours in vitro.
  
  
  RESULTS
  The collagen phygocytosis of hPDLF was increased significantly by 0.1 microg/mL LPS (P < 0.05).
  
  
  CONCLUSIONS
  This study indicates that P. gingivalis LPS may enhance the degradation of collagen by stimulating the phagocytic activity of the hPDLF in periodontitis.
authors: Stomatological Department, Xiangya Hospital of Central South University, Changsha 410008, China.
authors: Chang-yun
authors: CY
authors: Fang
authors: Zheng
authors: Z
authors: Su
authors: Lei
authors: L
authors: Chen
authors: Ming-wen
authors: MW
authors: Fan
authors: Xin-chun
authors: XC
authors: Jian
authors: Zhi
authors: Z
authors: Chen
mesh_terms: D003094:Collagen; D005347:Fibroblasts; D005881:Gingiva; D006801:Humans; D015850:Interleukin-6; D008070:Lipopolysaccharides; D010513:Periodontal Ligament; D010518:Periodontitis; D010587:Phagocytosis; D016966:Porphyromonas gingivalis
chemical_list: D015850:Interleukin-6; D008070:Lipopolysaccharides; D003094:Collagen