Prevalence of open-angle glaucoma in Greece: the Thessaloniki Eye Study.
OBJECTIVE
To estimate the prevalence of open-angle glaucoma (OAG) in a population-based sample of subjects 60 years of age or older in Thessaloniki, Greece.


METHODS
Cross-sectional population-based study.


METHODS
Subjects randomly identified from municipality registers in Thessaloniki underwent a complete ophthalmologic examination. Glaucoma was defined in two ways. Definition 1 was based on the presence of both glaucomatous optic disk and confirmed glaucomatous visual field defect. Subjects also were classified as having glaucoma when the clinical judgment was strongly in favor of the presence of glaucoma even though the strict criteria were not fulfilled (definition 2).


RESULTS
Of the 3,617 eligible subjects, 2,554 (71%) participated. The prevalence of OAG was 3.8% and 5.5% by definitions 1 and 2, respectively. The prevalence of primary OAG was 2.7% and 3.8% by definitions 1 and 2, respectively, and the prevalence of pseudoexfoliation glaucoma (PEXG) was 1.1% and 1.7% by definitions 1 and 2, respectively. Pseudoexfoliation was present in 11.9% of participants, whereas 15.2% among those with pseudoexfoliation had PEXG.


CONCLUSIONS
The prevalence of OAG in the Thessaloniki Eye Study (TES) is similar or slightly higher compared with other population-based studies in White persons. The overall slightly higher prevalence of OAG in the TES compared with other studies may be attributed to the high prevalence of PEXG in the TES.
Topouzis
Fotis
F
II Department of Ophthalmology, Aristotle University of Thessaloniki, Thessaloniki, Greece. ftopouzis@otenet.gr
Wilson
M Roy
MR
Harris
Alon
A
Anastasopoulos
Eleftherios
E
Yu
Fei
F
Mavroudis
Leonidas
L
Pappas
Theofanis
T
Koskosas
Archimidis
A
Coleman
Anne L
AL
D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D003430:Cross-Sectional Studies; D017889:Exfoliation Syndrome / Q000175:diagnosis / Q000453:epidemiology; D005240:Feasibility Studies; D005260:Female; D005902:Glaucoma, Open-Angle / Q000175:diagnosis / Q000453:epidemiology*; D006115:Greece / Q000453:epidemiology; D006801:Humans; D007429:Intraocular Pressure; D008297:Male; D008875:Middle Aged; D009898:Optic Disk / Q000473:pathology; D009901:Optic Nerve Diseases / Q000175:diagnosis / Q000453:epidemiology; D015995:Prevalence; D017678:Sex Distribution; D014065:Tonometry, Ocular