A divergent synthesis of gamma-iminolactones, dihydroquinolin-2-ones, and gamma-lactames from beta-hydroxymethylcyclopropanylamides.
Gamma-iminolactones 2, dihydroquinolin-2-ones 3, and gamma-lactames 4 have been synthesized starting from beta-hydroxymethylcyclopropanylamides 1, mediated by SnCl4/NaI/NEt3, BF3.OEt2, and TiCl4/NEt3. The corresponding products 2, 3, and 4 were produced, respectively, in high to excellent yields.
Xiong
Tao
T
Department of Chemistry, Northeast Normal University, Changchun, 130024, People's Republic of China.
Zhang
Qian
Q
Zhang
Zhiguo
Z
Liu
Qun
Q