Cystic carcinoma ex pleomorphic adenoma of the lacrimal gland.
In a 48-year-old male patient, a well-circumscribed, round tumor in the lacrimal fossa was detected by CT. During total excision of the tumor, a wall of the tumor ruptured, resulting in leakage of the fluid contents. The wall of the tumor formed a cyst that contained residual yellowish fluid. Histologically, the cyst wall included an adenocarcinomatous component and a focus of pleomorphic adenoma. The tumor was diagnosed as a carcinoma ex pleomorphic adenoma of the lacrimal gland. The carcinoma cells showed positive immunoreactivity for androgen receptor and BRST-2, indicating that the tumor was equivalent to a salivary duct carcinoma. Postoperatively, the patient underwent involved field irradiation. This case demonstrates that a carcinoma ex pleomorphic adenoma of the lacrimal gland may develop in a cyst.
Takahira
Masayuki
M
Department of Ophthalmology, Kanazawa University School of Medicine, Kanazawa, Japan. takahira@kenroku.kanazawa-u.ac.jp
Minato
Hiroshi
H
Takahashi
Mami
M
Karino
Kousei
K
Sugiyama
Kazuhisa
K
D008949:Adenoma, Pleomorphic / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D003528:Carcinoma, Adenoid Cystic / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D005134:Eye Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D006801:Humans; D007766:Lacrimal Apparatus Diseases / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D014057:Tomography, X-Ray Computed