title: The ansacarbamitocins: polar ansamitocin derivatives.
abstract: The ansacarbamitocins are a new family of maytansinoids that are unusually substituted with a glucose subunit and two carbamate functional groups and exhibit modest activity against some agricultural fungal disease organisms. Ansacarbamitocins A-F ( 1- 6) all consist of the same macrocyclic core as the ansamitocins, with variation occurring on the glucose unit, while ansacarbamitocins A1 and B1 ( 7, 8) additionally lack the epoxide group on C-4 and C-5.
authors: Dow AgroSciences, 9330 Zionsville Road, Indianapolis, Indiana 46268, USA.
authors: Carl E
authors: CE
authors: Snipes
authors: Dennis O
authors: DO
authors: Duebelbeis
authors: Monica
authors: M
authors: Olson
authors: Donald R
authors: DR
authors: Hahn
authors: William H
authors: WH
authors: Dent
authors: Jeffrey R
authors: JR
authors: Gilbert
authors: Todd L
authors: TL
authors: Werk
authors: George E
authors: GE
authors: Davis
authors: Rebecca
authors: R
authors: Lee-Lu
authors: Paul R
authors: PR
authors: Graupner
mesh_terms: D000192:Actinomycetales / Q000737:chemistry*; D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000145:classification / Q000302:isolation & purification* / Q000494:pharmacology; D001203:Ascomycota / Q000187:drug effects; D008453:Maytansine / Q000031:analogs & derivatives* / Q000737:chemistry / Q000145:classification / Q000302:isolation & purification / Q000494:pharmacology; D015394:Molecular Structure; D013329:Structure-Activity Relationship
chemical_list: D000900:Anti-Bacterial Agents; D008453:Maytansine; C015682:ansamitocins