title: Flavonoid glycosides from Prunus armeniaca and the antibacterial activity of a crude extract.
abstract: Investigations on the chemical constituents of the fruits of Prunus armeniaca have led to the isolation of two new flavonoid glycosides, 4',5,7-trihydroxy flavone-7-O-[beta-D-mannopyranosyl (1'''-->2")]-beta-D-allopyranoside (1) and 3,4',5,7-tetrahydroxy-3',5'-di-methoxy flavone 3-O-[alpha-L-rhamnopyranosyl (1'''-->6")]-beta-D-galactopyranoside (2), from the butanolic fraction of the fruits. The butanolic extract exhibited antibacterial activity against both Gram positive and Gram negative bacteria. The structures of these compounds were elucidated through spectral studies, including 2D-NMR (COSY, NOESY, J-resolved), HMQC and HMBC experiments.
authors: Department of Chemistry, Faculty of Science, University of Karachi, Karachi, Pakistan.
authors: Fahima
authors: F
authors: Rashid
authors: Rehana
authors: R
authors: Ahmed
authors: Azhar
authors: A
authors: Mahmood
authors: Zaheer
authors: Z
authors: Ahmad
authors: Nazia
authors: N
authors: Bibi
authors: Shahana Urooj
authors: SU
authors: Kazmi
mesh_terms: D000900:Anti-Bacterial Agents / Q000302:isolation & purification / Q000494:pharmacology; D005419:Flavonoids / Q000302:isolation & purification / Q000494:pharmacology; D005638:Fruit / Q000737:chemistry; D006027:Glycosides / Q000302:isolation & purification / Q000494:pharmacology; D006090:Gram-Negative Bacteria / Q000187:drug effects; D006094:Gram-Positive Bacteria / Q000187:drug effects; D009682:Magnetic Resonance Spectroscopy; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D027861:Prunus / Q000737:chemistry*
chemical_list: C523768:3,4',5,7-tetrahydroxy-3',5'-di-methoxy flavone 3-O-(alpha-L-rhamnopyranosyl (1'''-6''))-beta-D-galactopyranoside; C523769:4',5,7-trihydroxy flavone-7-O-(beta-D-mannopyranosyl (1'''-2''))-beta-D-allopyranoside; D000900:Anti-Bacterial Agents; D005419:Flavonoids; D006027:Glycosides