title: Retaining synaptic AMPARs.
abstract: Endocytosis, exocytosis, and lateral diffusion are key mechanisms for AMPA receptor trafficking. Endocytosis of AMPARs and other postsynaptic proteins has been proposed to occur at specific endocytic zones (EZs), but the mechanisms that regulate this process are not at all clear. In this issue of Neuron, Lu et al. show that correct synaptic EZ positioning requires links between the GTPase dynamin-3 and the Homer/Shank complex.
authors: MRC Centre for Synaptic Plasticity, Department of Anatomy, School of Medical Sciences, University of Bristol, Bristol BS8 1TD, UK.
authors: Frédéric
authors: F
authors: Jaskolski
authors: Stéphane
authors: S
authors: Martin
authors: Jeremy M
authors: JM
authors: Henley
mesh_terms: D000818:Animals; D034286:Dynamin III / Q000502:physiology; D004705:Endocytosis / Q000502:physiology; D005089:Exocytosis / Q000502:physiology; D020558:GTP Phosphohydrolases / Q000502:physiology; D006801:Humans; D009474:Neurons / Q000378:metabolism*; D018091:Receptors, AMPA / Q000378:metabolism*; D013569:Synapses / Q000502:physiology*; D022161:Transport Vesicles / Q000502:physiology
chemical_list: D018091:Receptors, AMPA; D020558:GTP Phosphohydrolases; D034286:Dynamin III