FK506 induces interleukin-6 secretion from UVB irradiated cultured human keratinocytes via p38 mitogen-activated protein kinase pathway: implication on mechanisms of tacrolimus-induced skin irritation.
Lan
Cheng-Che E
CC
Yu
Hsin-Su
HS
Huang
Shu-Mei
SM
Wu
Ching-Shuang
CS
Chen
Gwo-Shing
GS
D002470:Cell Survival / Q000187:drug effects; D002478:Cells, Cultured; D003872:Dermatitis / Q000188:drug therapy; D004305:Dose-Response Relationship, Drug; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects* / Q000494:pharmacology; D015850:Interleukin-6 / Q000378:metabolism*; D016209:Interleukin-8 / Q000378:metabolism; D015603:Keratinocytes / Q000187:drug effects / Q000378:metabolism* / Q000528:radiation effects; D010766:Phosphorylation / Q000187:drug effects / Q000528:radiation effects; D016559:Tacrolimus / Q000009:adverse effects* / Q000494:pharmacology; D014466:Ultraviolet Rays; D048051:p38 Mitogen-Activated Protein Kinases / Q000378:metabolism*
D007166:Immunosuppressive Agents; D015850:Interleukin-6; D016209:Interleukin-8; D048051:p38 Mitogen-Activated Protein Kinases; D016559:Tacrolimus