[Evaluation of liquid based cytology test (LCT) in avoiding medical tangles].
OBJECTIVE
To evaluate of liquid based cytology test (LCT) in avoiding medical tangles.


METHODS
One thousand five hundred five thirty one cases, which were collected from out-patients of precancerous lesions of uterine cervix, were randomly divided into three groups based on different smear preparation: LCT method was used in two groups (one with ThinPrep kit and one with ArtoBrain kit), conventional Papauicolaou smear (PS) was used in one group. All cases of abnormal cervical smears were identified by cytologic test underwent colposcopic examination and colopscopically multiple biopsy. Results of test were analyzed by software SPSS 11.0.


RESULTS
Significant diference were found between LCT method and PS method compared by index of satifacation, sensitivity, specificity, accuracy, false negative rate and erroneous diagnosis rate (P < 0.05, but no difference were found between two LCT groups (ThinPrep kit and ArtoBrain kit).


CONCLUSIONS
LCT method can improve diagnostic level of precancerous lesions of uterine cervix either tested by ThinPrep kit or ArtoBrain kit, so have the powerfull value to avoid medical tangles.
Liu
Bao-qin
BQ
Medical College of Shanghai Jiaotong University, Shanghai 200025, China. qinqin0508@126.com
Yan
Zhao-wen
ZW
Yao
Hong-xia
HX
Cai
Ji-feng
JF
D000328:Adult; D000368:Aged; D001706:Biopsy / Q000379:methods; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis* / Q000473:pathology; D002584:Cervix Uteri / Q000473:pathology*; D005260:Female; D006801:Humans; D008403:Mass Screening / Q000379:methods; D019300:Medical Errors / Q000331:legislation & jurisprudence / Q000517:prevention & control*; D008875:Middle Aged; D012680:Sensitivity and Specificity; D002583:Uterine Cervical Neoplasms / Q000175:diagnosis* / Q000473:pathology; D014626:Vaginal Smears / Q000379:methods*; D055815:Young Adult; D002578:Uterine Cervical Dysplasia / Q000175:diagnosis / Q000473:pathology