title: Retinal pigment epithelial tear in polypoidal choroidal vasculopathy.
abstract: OBJECTIVE
  To study the clinical characteristics of tears of the retinal pigment epithelium (RPE) in eyes with polypoidal choroidal vasculopathy (PCV).
  
  
  METHODS
  The authors report eight eyes of eight patients with PCV that had tears of the RPE. These were examined with angiography and tomography.
  
  
  RESULTS
  Eight eyes of eight patients (seven men and one woman) had RPE tears at the margin of a serosanguineous pigment epithelial detachment (PED) associated with PCV. Tears of the RPE were detected at the initial visit in one eye and during follow-up without any treatment in five eyes. In two eyes, the RPE tears were detected 3 months and 6 months, respectively, after photodynamic therapy. In all eyes, the RPE tears were detected at the side opposite to the polypoidal lesions of the PEDs, and the fovea was not involved in the RPE tear. Visual acuity in the seven eyes without RPE tears on presentation ranged from 20/100 to 20/16 (median, 20/32). During follow-up, three of these eyes lost three or more lines of vision. At the final examination, while three of these eyes had visual acuity of 20/25 or better, the other four had visual acuity of 20/200 or worse.
  
  
  CONCLUSIONS
  In eyes with PCV, RPE tears can occur at the margin of serosanguineous PEDs-either spontaneously or after photodynamic therapy.
authors: Department of Ophthalmology, Kyoto University Graduate School of Medicine, Kyoto, Japan. tujikawa@kuhp.kyoto-u.ac.jp
authors: Akitaka
authors: A
authors: Tsujikawa
authors: Yasuhiko
authors: Y
authors: Hirami
authors: Hideo
authors: H
authors: Nakanishi
authors: Yumiko
authors: Y
authors: Ojima
authors: Hiroko
authors: H
authors: Aikawa
authors: Hiroshi
authors: H
authors: Tamura
authors: Atsushi
authors: A
authors: Otani
authors: Nagahisa
authors: N
authors: Yoshimura
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002829:Choroid / Q000098:blood supply*; D015862:Choroid Diseases / Q000150:complications* / Q000175:diagnosis; D004396:Coloring Agents; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D007208:Indocyanine Green; D008297:Male; D008875:Middle Aged; D016491:Peripheral Vascular Diseases / Q000150:complications* / Q000175:diagnosis; D010778:Photochemotherapy; D010857:Pigment Epithelium of Eye / Q000473:pathology*; D012167:Retinal Perforations / Q000175:diagnosis / Q000209:etiology*; D012189:Retrospective Studies; D041623:Tomography, Optical Coherence; D014792:Visual Acuity
chemical_list: D004396:Coloring Agents; D007208:Indocyanine Green