Some biochemical parameters of blood plasma of turkey-hens following administration of 1,2,4-triasole derivative.
The present study involved 180 slaughter turkey-hens of heavy Big-6 type divided into four groups (in triplicate repetition for 15 birds). All the birds were fed with the same standard full-dose mixtures in 5-stage system. The turkey-hens of groups I, II and III were given 1,2,4-triasole derivative (3-(2-pyridil)-4-phenyl-1,2,4-triasole-5-carboxylic acid), which has antibacterial, antifungal and immunomodulating properties, in amount of 50, 75 and 100 microg per 1 dm3 of water. Group IV--control was given water without the additive. The 1,2,4-triasole derivative was given to drinking water, starting from the first day of bird's life and for the whole rearing period. The present results of biochemical analysis of blood plasma showed that addition of examined substance significantly reduced concentration of protein, glucose, triglycerides and uric acid as compared to control. It was stated that tested 1,2,4-triasole derivative elevated the level of HDL fraction percentage and alkaline phosphatase activity in blood plasma.
Krauze
M
M
Department of Biochemistry and Toxicology, Faculty of Animal Biology and Breeding, University of Agriculture, Akademicka 13, 20-950 Lublin, Poland. m.m.krauze@poczta.fm
Truchliński
J
J
Cendrowska-Pinkosz
M
M
D000284:Administration, Oral; D000818:Animals; D000890:Anti-Infective Agents / Q000008:administration & dosage / Q000097:blood / Q000494:pharmacology*; D001774:Blood Chemical Analysis; D001786:Blood Glucose / Q000187:drug effects; D001798:Blood Proteins / Q000187:drug effects; D004305:Dose-Response Relationship, Drug; D005260:Female; D014230:Triazoles / Q000008:administration & dosage / Q000097:blood / Q000494:pharmacology*; D014280:Triglycerides / Q000378:metabolism; D014422:Turkeys; D014527:Uric Acid / Q000378:metabolism
D000890:Anti-Infective Agents; D001786:Blood Glucose; D001798:Blood Proteins; D014230:Triazoles; D014280:Triglycerides; D014527:Uric Acid; C045575:1,2,4-triazole