title: Alpha-ketoglutarate is the precursor of L-2-hydroxyglutarate.
authors: Henri
authors: H
authors: Brunengraber
mesh_terms: D000429:Alcohol Oxidoreductases / Q000172:deficiency / Q000235:genetics / Q000378:metabolism*; D000818:Animals; D003600:Cytosol / Q000201:enzymology / Q000378:metabolism; D005977:Glutarates / Q000378:metabolism* / Q000652:urine; D006801:Humans; D007656:Ketoglutaric Acids / Q000378:metabolism*; D007700:Kinetics; D008099:Liver / Q000201:enzymology / Q000378:metabolism*; D008214:Lymphocytes / Q000201:enzymology / Q000378:metabolism*; D008291:Malate Dehydrogenase / Q000235:genetics / Q000378:metabolism*; D008661:Metabolism, Inborn Errors / Q000201:enzymology / Q000235:genetics / Q000378:metabolism*; D008930:Mitochondria, Liver / Q000201:enzymology / Q000378:metabolism; D010084:Oxidation-Reduction; D011994:Recombinant Proteins / Q000378:metabolism
chemical_list: D005977:Glutarates; D007656:Ketoglutaric Acids; D011994:Recombinant Proteins; C019417:alpha-hydroxyglutarate; D000429:Alcohol Oxidoreductases; D008291:Malate Dehydrogenase; C023858:2-hydroxyglutarate dehydrogenase; C506763:L2HGDH protein, human