title: Use of ultrasound measurement of the inferior vena cava diameter as an objective tool in the assessment of children with clinical dehydration.
abstract: OBJECTIVE
  Bedside ultrasonography (US) measurement of the inferior vena cava (IVC) and aorta (Ao) may be useful in objectively assessing children with dehydration. The objectives of this study were 1) to compare the IVC and Ao diameters (IVC/Ao) ratio of dehydrated children with controls and 2) to compare the IVC/Ao ratio before and after intravenous (i.v.) rehydration in children with dehydration.
  
  
  METHODS
  This prospective observational study was performed in an urban pediatric emergency department. Children between 6 months and 16 years of age with clinical evidence of dehydration were enrolled. Bedside US measurements of the IVC and Ao were taken before and immediately after i.v. fluids were administered. An age-, gender-, and weight-matched control without dehydration was enrolled for each subject. The IVC/Ao ratios of subjects and controls were compared using Wilcoxon signed rank test, as were the ratios before and after i.v. hydration for each subject.
  
  
  RESULTS
  Thirty-six pairs of subjects and matched controls were enrolled. The IVC/Ao ratios in the subjects were lower as compared with controls (mean of 0.75 vs. 1.01), with a mean difference of 0.26 (95% confidence interval = 0.18 to 0.35). In subjects, the IVC/Ao ratios were significantly lower before i.v. hydration (mean of 0.75 vs. 1.09), with a mean difference of 0.34 (95% confidence interval = 0.29 to 0.39).
  
  
  CONCLUSIONS
  As measured by bedside US measurement, the IVC/Ao ratio is lower in children clinically assessed to be dehydrated. Furthermore, it increases with administration of i.v. fluid boluses.
authors: Section of Emergency Medicine, Department of Pediatrics, Yale University School of Medicine, New Haven, CT, USA. lei.chen@yale.edu
authors: Lei
authors: L
authors: Chen
authors: Yunie
authors: Y
authors: Kim
authors: Karen A
authors: KA
authors: Santucci
mesh_terms: D000293:Adolescent; D001011:Aorta / Q000000981:diagnostic imaging; D002648:Child; D002675:Child, Preschool; D003681:Dehydration / Q000175:diagnosis* / Q000209:etiology / Q000628:therapy; D005260:Female; D005767:Gastrointestinal Diseases / Q000150:complications; D006801:Humans; D007223:Infant; D007262:Infusions, Intravenous; D008297:Male; D009929:Organ Size; D019095:Point-of-Care Systems; D011446:Prospective Studies; D012680:Sensitivity and Specificity; D012965:Sodium Chloride / Q000008:administration & dosage; D014463:Ultrasonography; D014682:Vena Cava, Inferior / Q000000981:diagnostic imaging*
chemical_list: D012965:Sodium Chloride