title: Reliéva, a Mahonia aquifolium extract for the treatment of adult patients with atopic dermatitis.
abstract: This clinical study was conducted to determine the efficacy and safety of Reliéva cream in adult patients with atopic dermatitis (eczema). This was an open-label trial in 42 patients with atopic dermatitis treated for 12 weeks with Reliéva cream (a homeopathic product containing Psorberine, a proprietary Mahonia aquifolium extract). Efficacy and safety was assessed using Eczema Area and Severity Index scores and a Subject Reported Evaluation of Treatment. The results showed significant (P < 0.05) improvements with respect to Eczema Area and Severity Index scores by comparison to subjects' baseline scores. In addition, subjects responding to a posttreatment evaluation questionnaire indicated a substantial benefit when rating effectiveness, itching, and appearance as a result of using the study preparation. Reliéva cream appears to be a safe and effective treatment for adult patients with atopic dermatitis (eczema).
authors: Dermatology and Cosmetic Center of Rochester, Rochester, NY, USA.
authors: Howard
authors: H
authors: Donsky
authors: Don
authors: D
authors: Clarke
mesh_terms: D000279:Administration, Cutaneous; D000328:Adult; D000368:Aged; D003876:Dermatitis, Atopic / Q000188:drug therapy*; D005260:Female; D006801:Humans; D008081:Liposomes; D028143:Mahonia / Q000737:chemistry*; D008297:Male; D008875:Middle Aged; D009824:Ointments; D008517:Phytotherapy; D010936:Plant Extracts / Q000009:adverse effects / Q000627:therapeutic use*; D011537:Pruritus / Q000188:drug therapy / Q000209:etiology; D012720:Severity of Illness Index
chemical_list: D008081:Liposomes; D009824:Ointments; D010936:Plant Extracts