title: Spontaneous spinal epidural hematoma: analysis of 23 cases.
abstract: BACKGROUND
  Spontaneous spinal epidural hematoma is a rare but disabling disease. To explore its characters and find out what factors influence the prognosis, we gave a retrospective analysis of 23 patients in our department in the past 8 years.
  
  
  METHODS
  Spontaneous spinal epidural hematoma was diagnosed by taking MRIs of patients without surgical management or by histopathological examination. We registered patient's case history, laboratory examination, radiological image, treatment, pathological result, and prognosis after 3 months and gave them nonparameter analysis.
  
  
  RESULTS
  Primary neurological status and progressive intervals have correlation with prognosis (P< .01), and the latter less than 12 hours predict worse prognosis (P= .032). Spinal edema in MRI predicts pessimistic prognosis (P= .013). Long hematoma predicts worse prognosis (P= .02). Preoperative interval, emphasized by other authors, has no statistical correlation with prognosis in this study (P= .832). Finally, patients with a single hematoma or hematoma mingled with other spinal disturbance have the same prognosis (P= .065).
  
  
  CONCLUSIONS
  The primary neurological status, progressive interval, spinal edema, and size of hematoma will influence the prognosis of the patient with SSEH. The major treatment is surgical intervention, and it should be operated as soon as possible to avoid the aggravation of neurological status. Conservative treatment is not considered unless patient's neurological deficiency has relieved in the early period.
authors: Department of Neurosurgery, West China Hospital, Sichuan University, Chengdu, PR China.
authors: Zhan
authors: Z
authors: Liu
authors: Qingfang
authors: Q
authors: Jiao
authors: Jianguo
authors: J
authors: Xu
authors: Xiang
authors: X
authors: Wang
authors: Sanzhong
authors: S
authors: Li
authors: Chao
authors: C
authors: You
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D020785:Central Nervous System Vascular Malformations / Q000453:epidemiology; D002648:Child; D019299:Decompression, Surgical / Q000379:methods; D004185:Disability Evaluation; D018450:Disease Progression; D004487:Edema / Q000453:epidemiology; D005260:Female; D046748:Hematoma, Epidural, Spinal / Q000453:epidemiology / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D019635:Neurosurgical Procedures / Q000379:methods; D011300:Preoperative Care; D011379:Prognosis; D012720:Severity of Illness Index; D013997:Time Factors