title: [Physiotherapeutic and rehabilitation therapy for ankylosing spondylitis. Status quo and are they still necessary in the age of anti-cytokine therapy?].
abstract: Ankylosing spondylitis (AS) is one of the most common chronic inflammatory rheumatic diseases characterized by erosions and bone proliferation with consecutive morphologic and functional deficits. Physiotherapeutic and rehabilitation measures are often necessary for AS patients for their whole life. In recent years, biologicals have substantially improved the outcome in AS patients, but their positive influence on vertebral and joint functions still requires differential indicative physiotherapeutic strategies and rehabilitation, in most cases in combination with effective analgesic and anti-inflammatory medication. Although physical therapy and rehabilitation have not been investigated in large controlled trials, they are essential for the multimodal therapeutic concept of AS.
authors: Abteilung Rheumatologie, Klinische Immunologie, Physikalische Medizin und Osteologie, Kerckhoff-Klinik, Benekestrasse 2-8, Bad Nauheim, Germany. u.lange@kerckhoff-klinik.de
authors: U
authors: U
authors: Lange
authors: B
authors: B
authors: Kürten
authors: U
authors: U
authors: Müller-Ladner
authors: C
authors: C
authors: Uhlemann
mesh_terms: D000893:Anti-Inflammatory Agents / Q000627:therapeutic use*; D003131:Combined Modality Therapy; D016207:Cytokines / Q000037:antagonists & inhibitors*; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D026741:Physical Therapy Modalities; D013167:Spondylitis, Ankylosing / Q000534:rehabilitation*
chemical_list: D000893:Anti-Inflammatory Agents; D016207:Cytokines; D007166:Immunosuppressive Agents