Contrast-enhanced ultrasound for diagnosis of prostate cancer and kidney lesions.
OBJECTIVE
Conventional ultrasonography of both, kidney and prostate, is limited due to the poor contrast of B-mode imaging for parenchymal disease and limited sensitivity of colour Doppler for the detection of capillaries and deep pedicular vessels. Contrast-enhanced ultrasound (CEUS) overcomes these limitations.


RESULTS
CEUS investigates the blood flow of the prostate, allows for prostate cancer visualization and for targeted biopsies. Comparisons between systematic and CEUS-targeted biopsies have shown that the targeted approach detects more cancers with a lower number of biopsy cores and with higher Gleason scores compared with the systematic approach. Also the kidney offers promising applications as CEUS improves the detection of abnormal microvascular and macrovascular disorders.


CONCLUSIONS
In recent literature CEUS has shown its value for diagnosis of both, prostate cancer and kidney lesions. This paper describes recent improvements and future perspectives of CEUS.
Mitterberger
Michael
M
Department of Urology, University of Innsbruck, Anichstrasse 35, A-6020 Innsbruck, Austria. michael.mitterberger@uibk.ac.at
Pelzer
Alexandre
A
Colleselli
Daniela
D
Bartsch
Georg
G
Strasser
Hannes
H
Pallwein
Leo
L
Aigner
Friedrich
F
Gradl
Johann
J
Frauscher
Ferdinand
F
D001706:Biopsy; D003287:Contrast Media; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D007668:Kidney / Q000098:blood supply / Q000000981:diagnostic imaging; D007674:Kidney Diseases / Q000000981:diagnostic imaging*; D008297:Male; D011467:Prostate / Q000098:blood supply / Q000000981:diagnostic imaging; D011471:Prostatic Neoplasms / Q000000981:diagnostic imaging*; D018608:Ultrasonography, Doppler; D018084:Ultrasonography, Interventional
D003287:Contrast Media