title: Isolated tubercular liver abscess in children treated with percutaneous isoniazid infusion.
abstract: Isolated Tubercular liver abscess is mainly reported in adult patients. We report two cases of isolated tubercular liver abscess in paediatric patients. Diagnosis was made by clinical and ultrasound guided aspiration of pus showing acid fast bacilli in one case. In second case, biopsy of the abscess wall was confirmatory. In both cases percutaneous drainage of pus and transcatheter infusion of Isoniazid was given. After two weeks of infusion no acid fast bacilli was detected and cavity size decreased. Direct infusion of anti-tubercular drugs is more efficient than systemic therapy alone. This is first of its kind in treating isolated tubercular abscess in paediatric patients. So, percutaneous infusion of anti-tubercular agents can be considered in the treatment of tubercular liver abscess.
authors: Department of Neonatal and Pediatric Surgery, SMS Medical College, S.P. Mother and Child Health Institute, Jaipur (Rajasthan). drpinaki_mch@yahoo.co.in
authors: Pinaki R
authors: PR
authors: Debnath
authors: Rakesh
authors: R
authors: Tripathi
authors: Deepak
authors: D
authors: Kandpall
authors: Basant
authors: B
authors: Kumar
authors: Ekta
authors: E
authors: Malik
authors: Shyam B
authors: SB
authors: Sharma
mesh_terms: D000279:Administration, Cutaneous; D000995:Antitubercular Agents / Q000008:administration & dosage / Q000009:adverse effects*; D002648:Child; D005260:Female; D006801:Humans; D007538:Isoniazid / Q000008:administration & dosage / Q000009:adverse effects*; D008099:Liver / Q000000981:diagnostic imaging / Q000187:drug effects / Q000382:microbiology / Q000473:pathology; D008100:Liver Abscess / Q000175:diagnosis / Q000209:etiology / Q000382:microbiology*; D008297:Male; D011859:Radiography; D014386:Tuberculosis, Hepatic / Q000188:drug therapy*
chemical_list: D000995:Antitubercular Agents; D007538:Isoniazid