[Clinical significance of measuring vitamin D metabolites].
For differential diagnosis of rickets/osteomalacia, it is essential to evaluate the level of circulating vitamin D metabolites. Although many other metabolites are present, it is clinically sufficient to assess 25 (OH) D and 1,25 (OH)(2)D. Low "normal" serum 25 (OH) D level does not cause rickets/osteomalacia, but could harm bone health. Such vitamin D insufficiency or inadequacy, can not be recognized unless serum 25 (OH) D is measured. Currently serum 25 (OH) D measurement is not reimbursed with the national health care system in Japan, to which an action should be taken.
Okazaki
Ryo
R
Teikyo University Chiba Medical Center, Third Department of Medicine.
D006801:Humans; D010018:Osteomalacia / Q000175:diagnosis; D012279:Rickets / Q000175:diagnosis; D014807:Vitamin D / Q000031:analogs & derivatives* / Q000097:blood; D014808:Vitamin D Deficiency / Q000175:diagnosis*
D014807:Vitamin D; C104450:25-hydroxyvitamin D