title: The LightWire technology for catheter-based interventions.
abstract: BACKGROUND
  The LightWire is a newly developed opto-acoustic coronary imaging guidewire that was designed to be used during angioplasty procedures and provide 'online' information on lumen and vessel wall dimensions.
  
  
  METHODS
  We designed in vitro models and performed animal trials to confirm proper device sensing capabilities and performance in the coronary arteries. This report focuses on maneuverability, compatibility with other catheterization devices, and vessel measurements.
  
  
  RESULTS
  Measurement ability was initially validated in vitro. Diameter measurements of coronary and peripheral arteries with and without stent based on ultrasound technology were then demonstrated in a pig model, whereas retaining easy navigation and maneuverability, as well as compatibility with other catheterization equipments. The LightWire device acquired proper and accurate multi-location measurements of coronary and femoral artery diameters.
  
  
  CONCLUSIONS
  Using a miniaturized opto-acoustic technology can aid incoronary imaging, while maintaining standard guidewire performances. Thus, the LightWire device holds promise as a diagnostic and guidance tool during coronary and peripheral angioplasty procedures.
authors: Rabin Medical Center, Petach Tikva, Israel. rkornowski@clalit.org.il
authors: Ran
authors: R
authors: Kornowski
authors: Hylton I
authors: HI
authors: Miller
authors: Rona
authors: R
authors: Shofti
authors: Carmel
authors: C
authors: Lehrer
authors: Avram
authors: A
authors: Matcovitch
authors: Elisabeth
authors: E
authors: Sadka
mesh_terms: D015906:Angioplasty, Balloon, Coronary / Q000295:instrumentation; D000818:Animals; D006328:Cardiac Catheterization; D017023:Coronary Angiography; D003324:Coronary Artery Disease / Q000000981:diagnostic imaging / Q000628:therapy; D003331:Coronary Vessels / Q000000981:diagnostic imaging*; D004867:Equipment Design; D005263:Femoral Artery / Q000000981:diagnostic imaging; D007090:Image Interpretation, Computer-Assisted; D008904:Miniaturization; D019047:Phantoms, Imaging; D015203:Reproducibility of Results; D015607:Stents; D013552:Swine; D018084:Ultrasonography, Interventional / Q000295:instrumentation*