Combined voriconazole plus caspofungin therapy for the treatment of probable Geotrichum pneumonia in a leukemia patient.
Infections by Geotrichum capitatum, occurring in leukemia patients, are rarely reported and generally are characterized by a poor prognosis. Here we reported a case of G. capitatum pneumonia in a patient with plasma cell leukemia, successfully treated with antifungal combination with voriconazole and caspofungin and supportive therapy.
Fianchi
L
L
Istituto di Ematologia, Università Cattolica del Sacro Cuore, Largo A. Gemelli 8, 00168, Rome, Italy. luanafianchi@libero.it
Montini
L
L
Caira
M
M
Voso
M T
MT
Maviglia
R
R
Posteraro
B
B
Pagano
L
L
D000368:Aged; D000935:Antifungal Agents / Q000008:administration & dosage* / Q000494:pharmacology / Q000627:therapeutic use; D000077336:Caspofungin; D004359:Drug Therapy, Combination; D054714:Echinocandins / Q000008:administration & dosage* / Q000494:pharmacology / Q000627:therapeutic use; D005260:Female; D005847:Geotrichosis / Q000188:drug therapy* / Q000382:microbiology; D005848:Geotrichum; D006801:Humans; D016867:Immunocompromised Host; D007952:Leukemia, Plasma Cell / Q000150:complications / Q000188:drug therapy; D055666:Lipopeptides; D008172:Lung Diseases, Fungal / Q000150:complications / Q000188:drug therapy* / Q000382:microbiology; D011743:Pyrimidines / Q000008:administration & dosage* / Q000494:pharmacology / Q000627:therapeutic use; D014230:Triazoles / Q000008:administration & dosage* / Q000494:pharmacology / Q000627:therapeutic use; D065819:Voriconazole
D000935:Antifungal Agents; D054714:Echinocandins; D055666:Lipopeptides; D011743:Pyrimidines; D014230:Triazoles; D000077336:Caspofungin; D065819:Voriconazole