title: TiO2 photocatalysis causes DNA damage via fenton reaction-generated hydroxyl radicals during the recovery period.
abstract: Here, we show that resistance of Escherichia coli to TiO2 photocatalysis involves defenses against reactive oxygen species. Results support the idea that TiO2 photocatalysis generates damage which later becomes deleterious during recovery. We found this to be partly due to DNA attack via hydroxyl radicals generated by the Fenton reaction during recovery.
authors.affiliation: Laboratoire de Chimie Bactérienne, UPR 9043, CNRS, 31 Chemin Joseph Aiguier, 13402 Marseille Cedex 20, France.
authors.forename: Gaëtan
authors.initials: G
authors.lastname: Gogniat
authors.forename: Sam
authors.initials: S
authors.lastname: Dukan
mesh_terms: D004249:DNA Damage; D004269:DNA, Bacterial / Q000737:chemistry / Q000187:drug effects / Q000528:radiation effects; D004926:Escherichia coli / Q000187:drug effects / Q000235:genetics / Q000378:metabolism*; D017665:Hydroxyl Radical / Q000737:chemistry*; D010777:Photochemistry; D017382:Reactive Oxygen Species / Q000737:chemistry / Q000378:metabolism; D014025:Titanium / Q000737:chemistry / Q000494:pharmacology*
chemical_list: D004269:DNA, Bacterial; D017382:Reactive Oxygen Species; C009495:titanium dioxide; D017665:Hydroxyl Radical; D014025:Titanium