title: Positive association between OLIG2 and schizophrenia in the Chinese Han population.
abstract: A recent study reported that OLIG2 had a significant association with schizophrenia in the UK population. We genotyped three variants scattered among the genomic region of OLIG2, namely rs1005573, rs762178 and rs1059004 in a sample consisting of 329 schizophrenia patients and 288 controls. The results provide further evidence that the SNP rs762178 in OLIG2 seems to be a potential candidate in altering risk for schizophrenia in the Chinese Han population and worthy of further replication and functional study.
authors.affiliation: Bio-X Center, Shanghai Jiao Tong University, PO Box 501, Haoran Building, 1954 Huashan Road, Shanghai, 200030, People's Republic of China.
authors.forename: Ke
authors.initials: K
authors.lastname: Huang
authors.forename: Wei
authors.initials: W
authors.lastname: Tang
authors.forename: Ruqi
authors.initials: R
authors.lastname: Tang
authors.forename: Zhao
authors.initials: Z
authors.lastname: Xu
authors.forename: Zhangdong
authors.initials: Z
authors.lastname: He
authors.forename: Zhiqiang
authors.initials: Z
authors.lastname: Li
authors.forename: Yifeng
authors.initials: Y
authors.lastname: Xu
authors.forename: Xingwang
authors.initials: X
authors.lastname: Li
authors.forename: Guang
authors.initials: G
authors.lastname: He
authors.forename: Guoying
authors.initials: G
authors.lastname: Feng
authors.forename: Lin
authors.initials: L
authors.lastname: He
authors.forename: Yongyong
authors.initials: Y
authors.lastname: Shi
mesh_terms: D000328:Adult; D044466:Asian People / Q000235:genetics*; D051792:Basic Helix-Loop-Helix Proteins / Q000235:genetics*; D016022:Case-Control Studies; D005260:Female; D008040:Genetic Linkage; D005828:Genetics, Population; D006801:Humans; D008297:Male; D008875:Middle Aged; D009419:Nerve Tissue Proteins / Q000235:genetics*; D000076104:Oligodendrocyte Transcription Factor 2; D020641:Polymorphism, Single Nucleotide; D012559:Schizophrenia / Q000235:genetics*
chemical_list: D051792:Basic Helix-Loop-Helix Proteins; D009419:Nerve Tissue Proteins; D000076104:Oligodendrocyte Transcription Factor 2; C405708:OLIG2 protein, human