Measurement of coronary sinus blood flow after first anterior myocardial infarction with transthoracic echocardiography and its correlation with wall motion scoring index.
OBJECTIVE
To measure the coronary sinus blood flow (CSBF) and coronary sinus velocity time integral (CSVTI) via transthoracic echocardiography (TTE) in patients with acute myocardial infarction (AMI) in association with the left ventricular ejection fraction (LVEF), and wall motion scoring index (WMSI).


METHODS
In this case-control study, 20 patients with anterior AMI and 20 healthy individuals as the control group, were studied in 6 months period from March to September 2005 in Madani Heart Center, Tabriz, Iran. All patients received the same treatment for AMI (such as fibrinolytic). The CSBF, CSVTI, WMSI, and tissue Doppler imaging (TDI) data were obtained via TTE and compared between the 2 groups.


RESULTS
Baseline variables were similar between the 2 groups (p>0.05). The CSBF in AMI group was 287.8 +/- 128 ml/min and in the control group was 415 +/- 127 ml/min (p=0.001). Also, CSVTI was significantly lower in AMI group than control group (11.16 +/- 2.85 and 17.56 +/- 2.72 mm, p=0.003). There was a significant correlation between CSBF and LVEF (r=0.52, p=0.01), WMSI (r=-0.77, p=0.0001) and CSBF and in-hospital mortality (r=0.58 p=0.03), also between CSVTI and LVEF (r=0.85, p=0.0001), WMSI (r=-0.57, p=0.0009) and in-hospital mortality rate (r=0.69, p=0.02). The CSBF and CSVTI had a good correlation with TDI findings: peak early diastolic velocity in the myocardium and peak systolic velocity in the myocardium).


CONCLUSIONS
Our study demonstrated a good correlation between measured CSBF and CSVTI by 2D- Doppler TTE and LVEF, WMSI, in-hospital mortality and TDI findings.
Toufan
Mehrnoush
M
Department of Cardiology, Cardiovascular Research Center of Tabriz University of Medical Sciences, Tabriz, Iran.
Samadikhah
Jahanbakhsh
J
Alizadeh-Asl
Azin
A
Azarfarin
Rasoul
R
Hakim
Seyed-Hadi
SH
Yaghoubi
Alireza
A
Farzam
Saeed
S
D000328:Adult; D000368:Aged; D001783:Blood Flow Velocity / Q000502:physiology; D054326:Coronary Sinus / Q000503:physiopathology*; D004452:Echocardiography; D005260:Female; D017052:Hospital Mortality; D006801:Humans; D007492:Iran; D008297:Male; D008875:Middle Aged; D009200:Myocardial Contraction / Q000502:physiology; D009203:Myocardial Infarction / Q000000981:diagnostic imaging* / Q000401:mortality / Q000503:physiopathology*; D012039:Regional Blood Flow / Q000502:physiology*; D013318:Stroke Volume / Q000502:physiology