Positive association between OLIG2 and schizophrenia in the Chinese Han population.
A recent study reported that OLIG2 had a significant association with schizophrenia in the UK population. We genotyped three variants scattered among the genomic region of OLIG2, namely rs1005573, rs762178 and rs1059004 in a sample consisting of 329 schizophrenia patients and 288 controls. The results provide further evidence that the SNP rs762178 in OLIG2 seems to be a potential candidate in altering risk for schizophrenia in the Chinese Han population and worthy of further replication and functional study.
Huang
Ke
K
Bio-X Center, Shanghai Jiao Tong University, PO Box 501, Haoran Building, 1954 Huashan Road, Shanghai, 200030, People's Republic of China.
Tang
Wei
W
Tang
Ruqi
R
Xu
Zhao
Z
He
Zhangdong
Z
Li
Zhiqiang
Z
Xu
Yifeng
Y
Li
Xingwang
X
He
Guang
G
Feng
Guoying
G
He
Lin
L
Shi
Yongyong
Y
D000328:Adult; D044466:Asian People / Q000235:genetics*; D051792:Basic Helix-Loop-Helix Proteins / Q000235:genetics*; D016022:Case-Control Studies; D005260:Female; D008040:Genetic Linkage; D005828:Genetics, Population; D006801:Humans; D008297:Male; D008875:Middle Aged; D009419:Nerve Tissue Proteins / Q000235:genetics*; D000076104:Oligodendrocyte Transcription Factor 2; D020641:Polymorphism, Single Nucleotide; D012559:Schizophrenia / Q000235:genetics*
D051792:Basic Helix-Loop-Helix Proteins; D009419:Nerve Tissue Proteins; D000076104:Oligodendrocyte Transcription Factor 2; C405708:OLIG2 protein, human