Adipose-derived stem cells and chondrogenesis.
Cartilage has only a very limited capacity to renew its original structure. Stem cells have been used to repair damaged cartilage, and recent studies have indicated that stem cells from adipose tissue are attractive cell sources that have the capacity of multipotentiality to differentiate into osteogenic, chondrogenic, myogenic, neurogenic and endothelial cells. Adipose-derived stem cells (ASC) have unique characteristics compared with stem cells from BM. At present, ASC have been studied to promote chondrogenesis. This review discusses the application of ASC to cartilage formation.
Wei
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Y
Institute of Orthopaedics and Traumatology, Xijing Hospital, The Fourth Military Medical University, Xi'an, People's Republic of China.
Sun
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X
Wang
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W
Hu
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Y
D000273:Adipose Tissue / Q000166:cytology* / Q000378:metabolism; D053687:Adult Stem Cells / Q000166:cytology / Q000378:metabolism / Q000637:transplantation; D000818:Animals; D015703:Antigens, CD / Q000378:metabolism; D001861:Bone Regeneration; D002356:Cartilage / Q000166:cytology* / Q000502:physiology; D018929:Cell Culture Techniques; D002454:Cell Differentiation; D019070:Cell Lineage; D054338:Cell Transdifferentiation; D020219:Chondrogenesis; D006801:Humans; D008562:Membrane Glycoproteins / Q000378:metabolism; D051379:Mice; D039902:Multipotent Stem Cells / Q000166:cytology / Q000378:metabolism / Q000637:transplantation; D015260:Neprilysin / Q000378:metabolism; D060245:Tetraspanin 29; D014162:Transfection; D016212:Transforming Growth Factor beta / Q000096:biosynthesis / Q000235:genetics; D019076:Transgenes
D015703:Antigens, CD; C554869:CD9 protein, human; C554870:Cd9 protein, mouse; D008562:Membrane Glycoproteins; D060245:Tetraspanin 29; D016212:Transforming Growth Factor beta; D015260:Neprilysin