[Genetic imprinting and embryonic development].
Erasure, establishment and maintenance of genetic imprinting are indispensable for normal embryonic development. All these processes depend on accurate expression and intimate cooperation of kinds of DNA methyltransferases. Many genetic syndromes and embryo developmental anomalies are caused by abnormality of genetic imprinting. Genetic imprinting is important for the nucleus totipotential of primordial germ cell, maturation of gamete,growth and development of embryo, structure and function of placenta as well as postnatal growth and development of individuals.
Yin
Li-jun
LJ
The Affiliated Obstetrics and Gynecology HospitalìCollege of Medicine, Zhejiang University, Hangzhou, China.
Huang
He-feng
HF
D000818:Animals; D019175:DNA Methylation; D015254:DNA Modification Methylases / Q000235:genetics / Q000378:metabolism; D047108:Embryonic Development / Q000235:genetics*; D018392:Genomic Imprinting / Q000235:genetics*; D006801:Humans; D009154:Mutation
D015254:DNA Modification Methylases