Differentiation of metastatic follicular thyroid cancer from hepatocellular carcinoma using Hep Par 1.
Hepatocellular carcinoma usually arises in a cirrhotic liver. Multiple hepatic nodules in a non-cirrhotic liver are more likely to be metastatic. The primary focus commonly arises from the gastrointestinal tract, breast or lung, but in the absence of these a primary liver pathology must be considered. The case is reported of a middle-aged woman presenting with multiple nodules on computed tomography with no clinically apparent primary for whom results of initial diagnostic investigations were potentially misleading.
Mullin
Emma J
EJ
University of Adelaide Department of Surgery, The Queen Elizabeth Hospital, Adelaide, South Australia, Australia.
Metcalfe
Matthew S
MS
Maddern
Guy J
GJ
D000328:Adult; D000911:Antibodies, Monoclonal; D006528:Carcinoma, Hepatocellular / Q000737:chemistry / Q000175:diagnosis* / Q000473:pathology; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007150:Immunohistochemistry / Q000379:methods*; D008113:Liver Neoplasms / Q000737:chemistry / Q000175:diagnosis* / Q000556:secondary; D009363:Neoplasm Proteins / Q000032:analysis* / Q000276:immunology; D013964:Thyroid Neoplasms / Q000737:chemistry / Q000175:diagnosis* / Q000473:pathology
D000911:Antibodies, Monoclonal; D009363:Neoplasm Proteins