Homotopic dynamics of telomeric loops in mammalian chromatids.
Asymmetric transfer of a solitonic kink between telomeric loops shared by template-replica chromatids is conceptualized in terms of homotopic dynamics. Downscaled to B-Z DNA these ideas lead to interesting possibilities regarding duplication and/or selective activation of genes located at or near DNA "hybrid" chiralities.
Jabbour
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MN
Department of Neurological Surgery, USC Keck School of Medicine, 2025 Zonal Avenue, RMR 424, Los Angeles, CA 90033, USA. mnjabbou@usc.edu
Matioli
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GT
D000705:Anaphase / Q000235:genetics; D000818:Animals; D002842:Chromatids / Q000235:genetics*; D004247:DNA / Q000235:genetics; D008322:Mammals / Q000235:genetics; D008957:Models, Genetic; D016615:Telomere / Q000235:genetics*
D004247:DNA