Central visfatin causes orexigenic effects in chicks.
Intracerebroventricular injection of visfatin caused increased feed intake and pecking efficiency, but did not affect water intake in chicks. Visfatin-treated chicks had increased c-Fos immunoreactivity in the lateral hypothalamus, decreased reactivity in the ventromedial hypothalamus and the dorsomedial hypothalamus, infundibular nucleus, periventricular nucleus, paraventricular nucleus were not affected. A low dose of visfatin increased locomotion. We conclude that intracerebroventricular injection of visfatin causes orexigenic effects in chicks.
Cline
Mark A
MA
Department of Biology (6931), Radford University, Radford, VA 24142, USA. mcline@radford.edu
Nandar
Wint
W
Prall
Brian C
BC
Bowden
Christie N
CN
Denbow
D Michael
DM
D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects*; D002645:Chickens / Q000502:physiology*; D004305:Dose-Response Relationship, Drug; D004435:Eating / Q000187:drug effects*; D005247:Feeding Behavior / Q000187:drug effects*; D007026:Hypothalamic Area, Lateral / Q000187:drug effects; D007276:Injections, Intraventricular / Q000379:methods; D008124:Locomotion / Q000187:drug effects; D054409:Nicotinamide Phosphoribosyltransferase / Q000008:administration & dosage*; D016760:Proto-Oncogene Proteins c-fos / Q000378:metabolism; D013997:Time Factors
D016760:Proto-Oncogene Proteins c-fos; D054409:Nicotinamide Phosphoribosyltransferase