title: Recognition of imidazoles by strapped zinc(II) porphyrin receptors: insight into the induced-fit mechanism.
abstract: Imidazole-porphyrin coordination has become an important tool in the design of self-assembled materials. A combination of spectrophotometric and stopped-flow techniques has been used to gain insight into the control of imidazole binding in the distal pocket of phenanthroline-strapped porphyrins. The binding studies of a variety of imidazole substrates in combination with both hindered and accessible receptors have permitted the determination of the thermodynamic and kinetic parameters associated with the imidazole binding.
authors.affiliation: Laboratoire de Physico-Chimie Bioinorganique, ULP-CNRS (UMR 7177), Institut de Chimie, ECPM, 25 rue Becquerel, 67200 Strasbourg, France.
authors.forename: Jeremy
authors.initials: J
authors.lastname: Brandel
authors.forename: Ali
authors.initials: A
authors.lastname: Trabolsi
authors.forename: Frédéric
authors.initials: F
authors.lastname: Melin
authors.forename: Mourad
authors.initials: M
authors.lastname: Elhabiri
authors.forename: Jean
authors.initials: J
authors.lastname: Weiss
authors.forename: Anne-Marie
authors.initials: AM
authors.lastname: Albrecht-Gary
mesh_terms: D007093:Imidazoles / Q000737:chemistry*; D008665:Metalloporphyrins / Q000737:chemistry*; D011956:Receptors, Cell Surface / Q000737:chemistry*
chemical_list: D007093:Imidazoles; D008665:Metalloporphyrins; D011956:Receptors, Cell Surface; C017802:zinc hematoporphyrin