[Which therapy for acute and chronic migrains?].
The onset of a migraine attack is associated with the activation of the trigemino-vascular system. Early intervention with triptans, which inhibit this activation is an effective treatment for migraine attacks. To avoid a cutaneous allodynia it is necessary to introduce as soon as possible the treatment with triptans. Drugs useful in the migraine prophylaxis tend to reduce the neuronal excitability in different areas of the central nervous system. The new definition of a chronic migraine is presented. This chronic migraine is frequently the result of an overuse of triptans. The practical aspects of the therapy of this specific migraine are described.
Regli
Franco
F
Clinique de Genolier, Genolier. Regli.Franco@bluewin.ch
Dewarrat
Annelise
A
D000208:Acute Disease; D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use; D000927:Anticonvulsants / Q000627:therapeutic use; D002908:Chronic Disease; D005632:Fructose / Q000031:analogs & derivatives / Q000627:therapeutic use; D006801:Humans; D006930:Hyperalgesia / Q000209:etiology / Q000517:prevention & control; D008881:Migraine Disorders / Q000150:complications / Q000188:drug therapy*; D000077236:Topiramate; D014363:Tryptamines / Q000627:therapeutic use
D000319:Adrenergic beta-Antagonists; D000927:Anticonvulsants; D014363:Tryptamines; D000077236:Topiramate; D005632:Fructose