[A case of the metastatic calcification of trachea, bronchus, and lung].
A 43-year-old man with chronic renal failure who had been treated by continuous ambulatory peritoneal dialysis (CAPD) was admitted to our hospital because of dry cough. Blood gas analysis showed hypoxemia and metabolic alkalosis. Laboratory data showed elevated levels of phosphorus, BNP, and KL-6. Lung function tests showed restrictive ventilatory failure and impairment of diffusing capacity. Chest CT revealed centrilobular ground-glass opacification in both lung fields, irregular reticular abnormality in left lung field, and calcification around the left shoulder joint. Bronchoscopy revealed a white protruding lesion in the trachea and bronchial membranous portion. Calcified metastasis in the bronchus and lung was confirmed by transbronchial and lung biopsy. Because of no improvement by administration of sevelamer, he started with hemodialysis once a week in addition to CAPD. Cough and bilateral ground-glass opacity were improved.
Miyahara
Yousuke
Y
Department of Respiratory Medicine, Saitama Cardiovascular and Respiratory Center.
Takayanagi
Noboru
N
Yoneda
Koichiro
K
Tsuchiya
Noriko
N
Morokawa
Nasa
N
Yamaguchi
Shozaburo
S
Tokunaga
Daido
D
Saitoh
Hiro
H
Kurashima
Kazuyoshi
K
Ubukata
Mikio
M
Yanagisawa
Tsutomu
T
Sugita
Yutaka
Y
D000328:Adult; D001706:Biopsy; D001982:Bronchial Diseases / Q000175:diagnosis*; D002114:Calcinosis / Q000175:diagnosis*; D006801:Humans; D054559:Hyperphosphatemia / Q000150:complications; D007676:Kidney Failure, Chronic / Q000150:complications / Q000628:therapy; D008168:Lung / Q000473:pathology; D008171:Lung Diseases / Q000175:diagnosis*; D008297:Male; D010531:Peritoneal Dialysis, Continuous Ambulatory; D013902:Radiography, Thoracic; D014133:Tracheal Diseases / Q000175:diagnosis*