Consecutive palladium-catalyzed Hiyama-Heck reactions in aqueous media under ligand-free conditions.
Symmetric and asymmetric (E)-1,2-diarylethenes are synthesized from aryl bromides by consecutive one-pot Hiyama-Heck reactions carried out in water and under air; the only additives required are sodium hydroxide, palladium acetate and poly(ethylene glycol), and the products are isolable in many cases by simple filtration of the water solution.
Gordillo
Alvaro
A
Departamento de Química Orgánica, Universidad de Alcalá, 28871 Alcalá de Henares (Madrid), Spain.
de Jesús
Ernesto
E
López-Mardomingo
Carmen
C