title: [Pulmonary function in patients with infiltrative pulmonary tuberculosis].
abstract: Vital capacity (VC), forced vital capacity (FVC), forced expiratory volume in 1 second (FEV1), FEV1/VC%, PEF, MEF25, MEF50, MEF75, TLC, TGV, pulmonary residual volume (PRV), R(aw), R(in),, R(ex), DLCO-SB, DLCO-SS, PaO2, and PaCO2 were determined in 103 patients with infiltrative pulmonary tuberculosis. Pulmonary dysfunction was detected in 83.5% of the patients. Changes were found in lung volumes and capacities in 63.1%, impaired bronchial patency and pulmonary gas exchange dysfunction were in 60.2 and 41.7%, respectively. The changes in pulmonary volumes and capacities appeared as increased PRV, decreased VC and FVC, and decreased and increased TGV and TLC; impaired bronchial patency presented as decreased PEF, MEF25, MEF50, MEF75, FEV1/VC% and increased R(aw) R(in), and R(ex); pulmonary gas exchange dysfunction manifested itself as reduced DLCO-SB, DLCO-SS, and PaO2 and decreased and increased PaCO2. The magnitude of the observed functional changes was generally slight. Significant disorders were observed rarely and very pronounced ones were exceptional.
authors.forename: V B
authors.initials: VB
authors.lastname: Nefedov
authors.forename: L A
authors.initials: LA
authors.lastname: Popova
authors.forename: E A
authors.initials: EA
authors.lastname: Shergina
mesh_terms: D000328:Adult; D005260:Female; D005541:Forced Expiratory Volume / Q000502:physiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D010991:Plethysmography; D011379:Prognosis; D011659:Pulmonary Gas Exchange / Q000502:physiology; D012720:Severity of Illness Index; D013147:Spirometry; D014397:Tuberculosis, Pulmonary / Q000503:physiopathology*; D014797:Vital Capacity / Q000502:physiology