Psychoactive drugs and neuroplasticity.
The influence of psychoactive drugs on neuroplasticity, especially on neurogenesis is reviewed. From psychopharmacological point of view most interesting results are those showing neurogenesis that neurogenesis is increased by SSRI. However, the role of serotonin system in neurogenesis as well as significance of neurogenesis in the beneficial effect of psychotropic drugs requires a lot of additional and new inventive research.
Lacković
Zdravko
Z
Laboratory of Molecular Neuropsychopharmacology, Department of Pharmacology & Croatian Brain Research Institute, University of Zagreb Medical School, Zagreb, Croatia. lac@mef.hr
D000818:Animals; D001921:Brain / Q000187:drug effects*; D002455:Cell Division / Q000187:drug effects; D003866:Depressive Disorder / Q000188:drug therapy; D006624:Hippocampus / Q000187:drug effects; D006801:Humans; D008322:Mammals; D001523:Mental Disorders / Q000188:drug therapy*; D009416:Nerve Regeneration / Q000187:drug effects; D009473:Neuronal Plasticity / Q000187:drug effects*; D009474:Neurons / Q000187:drug effects; D009830:Olfactory Bulb / Q000187:drug effects; D017367:Selective Serotonin Reuptake Inhibitors / Q000627:therapeutic use
D017367:Selective Serotonin Reuptake Inhibitors