Submandibular area metastasis from prostate small cell carcinoma with neuroendocrine differentiation.
Neuroendocrine differentiation in prostatic carcinomas generally confers a more aggressive clinical behavior and less favorable prognosis than usual prostatic carcinomas. In this article, we report a case of a 65-year-old man with prostatic carcinoma who had a metastasis of the submandibular area. His serum prostate-specific antigen level was reduced to below the normal range and carcinoembryonic antigen was increased. Pathologic specimens demonstrated a small cell carcinoma with neuroendocrine differentiation by immunohistochemical studies.
Xiao
Wen-lin
WL
Department of Oral and Maxillofacial Surgery, The Medical School Hospital of Qingdao University, Qingdao, the People's Republic of China.
Zhou
Fu-ting
FT
Feng
Yuan-yong
YY
Li
Ning-yi
NY
D000368:Aged; D018288:Carcinoma, Small Cell / Q000556:secondary*; D006801:Humans; D008297:Male; D011471:Prostatic Neoplasms / Q000473:pathology*; D013365:Submandibular Gland Neoplasms / Q000556:secondary*