title: A stereoselective intramolecular halo-etherification of chiral enamides in the synthesis of halogenated cyclic ethers.
abstract: A stereoselective halo-etherification of chiral enamides is described here. This work provides an approach to halogen containing cyclic ethers and reveals further mechanistic insights to the chemistry of chiral enamides.
authors.affiliation: Division of Pharmaceutical Sciencies and Department of Chemistry, Rennebohm Hall 777 Highland Avenue, University of Wisconsin, Madison, Wisconsin 53705-2222, USA.
authors.forename: Changhong
authors.initials: C
authors.lastname: Ko
authors.forename: Richard P
authors.initials: RP
authors.lastname: Hsung
authors.forename: Ziyad F
authors.initials: ZF
authors.lastname: Al-Rashid
authors.forename: John B
authors.initials: JB
authors.lastname: Feltenberger
authors.forename: Ting
authors.initials: T
authors.lastname: Lu
authors.forename: Jin-Haek
authors.initials: JH
authors.lastname: Yang
authors.forename: Yonggang
authors.initials: Y
authors.lastname: Wei
authors.forename: Craig A
authors.initials: CA
authors.lastname: Zificsak
mesh_terms: D004988:Ethers, Cyclic / Q000138:chemical synthesis*; D006846:Hydrocarbons, Halogenated / Q000138:chemical synthesis*; D008958:Models, Molecular; D015394:Molecular Structure
chemical_list: D004988:Ethers, Cyclic; D006846:Hydrocarbons, Halogenated