[Kikuchi-Fujimoto's disease: report of 5 cases and literature review].
Kikuchi-Fujimoto's disease or histiocytic necrotizing lymphadenitis is a benign disease predominantly occurring in young women which etiology remains unknown and revealed by cervical lymphadenitis and/or prolonged fever. It has rarely been reported in children. Among the 5 cases reported, 1 child had a systemic localization. The diagnosis is based on the histological examination of a lymph node biopsy. The disease course was spontaneously favourable in 2 cases; a corticotherapy was needed in 3 children. A pathogen agent was found in 2 patients. Kikuchi's disease can reveal or evolve into autoimmune disease particularly lupus, thus a long clinical and biological follow-up is necessary.
Adjaoud
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Service d'hématologie et d'oncologie pédiatriques, hôpital d'enfants Armand-Trousseau, Assistance publique-Hôpitaux de Paris, 26, avenue du Docteur-A.-Netter, 75012 Paris, France. daladjaoud@yahoo.fr
Boudjemaa
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Boccon-Gibod
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Leverger
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D000293:Adolescent; D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D019980:Amoxicillin-Potassium Clavulanate Combination / Q000627:therapeutic use; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001706:Biopsy; D002648:Child; D005260:Female; D020042:Histiocytic Necrotizing Lymphadenitis / Q000175:diagnosis* / Q000188:drug therapy; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology; D008297:Male
D000305:Adrenal Cortex Hormones; D000900:Anti-Bacterial Agents; D019980:Amoxicillin-Potassium Clavulanate Combination