title: Significant improvement of cardiac sympathetic function following cardiac support device implantation: illustration by 123I-MIBG scintigraphy.
abstract: Cardiac support device implantation is a new and promising therapy for refractory heart failure. If functional and echocardiographic modifications have largely been reported following this procedure, there is a paucity of information in the clinical setting about cellular abnormalities modifications during the 'reverse remodeling' process. We report for the first time a clinical measurement of cardiac sympathetic function using 123I-MIBG scintigraphy following cardiac support device implantation.
authors.affiliation: Nuclear Medicine Department, Hôpital Haut-Lévèque, Bordeaux Heart University Hospital, Avenue de Magellan, 33604 Bordeaux-Pessac, France.
authors.forename: Nathalie
authors.initials: N
authors.lastname: Valli
authors.forename: Louis
authors.initials: L
authors.lastname: Labrousse
authors.forename: Patricia
authors.initials: P
authors.lastname: Réant
authors.forename: Pierre
authors.initials: P
authors.lastname: Dos-Santos
mesh_terms: D019797:3-Iodobenzylguanidine; D006321:Heart / Q000000981:diagnostic imaging / Q000294:innervation*; D006333:Heart Failure / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000601:surgery*; D006353:Heart-Assist Devices; D006801:Humans; D007457:Iodine Radioisotopes; D008297:Male; D008875:Middle Aged; D011184:Postoperative Period; D013564:Sympathetic Nervous System / Q000503:physiopathology; D015899:Tomography, Emission-Computed, Single-Photon; D016896:Treatment Outcome
chemical_list: D007457:Iodine Radioisotopes; D019797:3-Iodobenzylguanidine