title: Prevalence and characteristics of diabetic polyneuropathy in Passo Fundo, South of Brazil.
abstract: OBJECTIVE
  The aim of the study was to investigate the prevalence of peripheral diabetic neuropathy (PDN) and associated characteristics among type 2 diabetic mellitus (DM2) patients in Passo Fundo, a city on Southern Brazil.
  
  
  METHODS
  A cross-sectional study was conducted with 340 patients with type 2 diabetes mellitus. Tests were performed to evaluate vibration (tuning fork), light touch (10-g monofilament), temperature, and pain (pinprick) sensations, as well as ankle reflexes and heel walking. The condition was classified as peripheral diabetic neuropathy when results in at least three of these tests were negative. The electrically induced Hoffmann reflex test was performed in a group of patients to define the criterion standard used in the assessment of clinical examination sensibility in the diagnosis of neuropathy. Sensitivity was 83%, specificity, 91%, positive predictive value, 63%, and negative predictive value, 90%. The monofilament, pinprick and deep tendon reflex were the most accurate tests in the diagnosis of neuropathy.
  
  
  RESULTS
  Seventy-five patients (22.1%) had peripheral diabetic neuropathy, nephropathy in 29.5% and retinopathy in 28.8%.
  
  
  CONCLUSIONS
  Logistic regression revealed that only duration of diabetes, creatinine and glycated hemoglobin concentrations were significantly associated with neuropathy.
authors.affiliation: School of Medicine, University of Passo Fundo, Passo Fundo, RS.
authors.forename: Gláucia Sarturi
authors.initials: GS
authors.lastname: Tres
authors.forename: Hugo R Kurtz
authors.initials: HR
authors.lastname: Lisbôa
authors.forename: Roger
authors.initials: R
authors.lastname: Syllos
authors.forename: Luis Henrique
authors.initials: LH
authors.lastname: Canani
authors.forename: Jorge Luiz
authors.initials: JL
authors.lastname: Gross
mesh_terms: D000368:Aged; D001938:Brazil / Q000453:epidemiology; D003430:Cross-Sectional Studies; D003924:Diabetes Mellitus, Type 2 / Q000150:complications*; D003928:Diabetic Nephropathies / Q000453:epidemiology / Q000209:etiology; D003929:Diabetic Neuropathies / Q000453:epidemiology* / Q000209:etiology; D003930:Diabetic Retinopathy / Q000453:epidemiology / Q000209:etiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011115:Polyneuropathies / Q000453:epidemiology* / Q000209:etiology; D015995:Prevalence; D012680:Sensitivity and Specificity; D012684:Sensory Thresholds / Q000502:physiology; D014110:Touch / Q000502:physiology