Inconsistencies in Neanderthal genomic DNA sequences.
Two recently published papers describe nuclear DNA sequences that were obtained from the same Neanderthal fossil. Our reanalyses of the data from these studies show that they are not consistent with each other and point to serious problems with the data quality in one of the studies, possibly due to modern human DNA contaminants and/or a high rate of sequencing errors.
Wall
Jeffrey D
JD
Institute for Human Genetics, University of California San Francisco, San Francisco, California, USA. wallj@humgen.ucsf.edu
Kim
Sung K
SK
D000483:Alleles; D000818:Animals; D004247:DNA / Q000032:analysis* / Q000235:genetics*; D004272:DNA, Mitochondrial / Q000032:analysis / Q000235:genetics; D005580:Fossils; D015186:Hominidae / Q000235:genetics*; D006801:Humans; D010802:Phylogeny; D011110:Polymorphism, Genetic / Q000235:genetics; D011156:Population Density; D017422:Sequence Analysis, DNA; D013997:Time Factors
D004272:DNA, Mitochondrial; D004247:DNA