title: A review of women with microinvasive cervical cancer in the Grampian region.
abstract: OBJECTIVE
  To review the diagnosis and treatment of women with microinvasive cervical cancer within a geographically defined population.
  
  
  METHODS
  A retrospective review of cervical cancer in the Grampian region identified 64 women diagnosed with microinvasive cervical cancer since 1991.
  
  
  RESULTS
  All of the women were referred with an abnormal smear, with invasion suspected on cytology in 12.5% of cases. With the addition of colposcopy, suspicion of invasion was noted in 23.5%. Most women (72%) were managed with conservative excision treatment of the cervix (large loop excision of the transformation zone or cone biopsy).
  
  
  CONCLUSIONS
  Long-term follow-up is vital, because 5 cases of cervical intraepithelial neoplasia and 1 recurrent cancer were detected up to 58 months after diagnosis.
authors.affiliation: Department of Obstetrics and Gynaecology, Aberdeen Royal Infirmary, Scotland, UK. marycairns@nhs.net
authors.forename: Mary
authors.initials: M
authors.lastname: Cairns
authors.forename: Margaret
authors.initials: M
authors.lastname: Cruickshank
mesh_terms: D000328:Adult; D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000473:pathology* / Q000601:surgery; D003127:Colposcopy; D005260:Female; D006801:Humans; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D012189:Retrospective Studies; D012606:Scotland; D002583:Uterine Cervical Neoplasms / Q000473:pathology* / Q000601:surgery