The final frontier: oxygen flux into muscle at exercise onset.
In humans at exercise onset, intramuscular phosphocreatine decreases immediately, whereas muscle oxygen (O2) uptake seems to rise after a delay of up to 15 s which is inconsistent with models of metabolic control. Novel microcirculatory investigations reveal that elevated capillary-to-myocyte O2 flux in rat muscle is, in fact, initiated simultaneously with contractions.
Poole
David C
DC
Department of Kinesiology, Kansas State University, Manhattan, KS 66506-5802, USA. poole@vet.ksu.edu
Ferreira
Leonardo F
LF
Behnke
Brad J
BJ
Barstow
Thomas J
TJ
Jones
Andrew M
AM
D015444:Exercise / Q000502:physiology*; D006439:Hemodynamics; D006801:Humans; D007700:Kinetics; D008833:Microcirculation / Q000502:physiology; D010100:Oxygen / Q000378:metabolism*; D010101:Oxygen Consumption / Q000502:physiology; D010725:Phosphocreatine; D014481:United States
D010725:Phosphocreatine; D010100:Oxygen