title: Chronic recurrent multifocal osteomyelitis presenting as acute scoliosis: a case report and review of literature.
abstract: Chronic relapsing multifocal osteomyelitis (CRMO) is a rare condition. It commonly affects the clavicle and pelvis. Rarely it can affect the spine. Spinal deformity due to CRMO is rare. We report a case of acute scoliosis due to CRMO. A 10-year-old girl with CRMO presented with acute painful scoliosis of her spine. She was neurologically intact. Imaging suggested a neoplastic process involving T10, L2 and L3. Further imaging and subsequent biopsy was performed and a diagnosis of CRMO was established. Spinal involvement with deformity is uncommon. It is commonly misdiagnosed as infection or a neoplasm and unnecessary aggressive surgical and antibiotic therapy instituted. A high index of suspicion is needed to diagnose this disease and thus manage it appropriately. This patient with a previously normal spine had a long right sided thoracic scoliosis. We think that the particular pattern of scoliosis was a protective mechanism to offload the right sided T10 vertebral pedicle. Prognosis is generally good although the disease can relapse and remit over many years. At 9 months follow up, the lesions were resolving and the deformity had resolved. CRMO presenting as acute scoliosis is rare and to our knowledge this is the second recognised case in the reported world literature.
authors.affiliation: Trauma and Orthopaedics, University Hospital of Wales, Heath Park Avenue, Cardiff, CF14 4XW, UK. kedar_deogao@yahoo.com
authors.forename: Kedar
authors.initials: K
authors.lastname: Deogaonkar
authors.forename: Adel
authors.initials: A
authors.lastname: Ghandour
authors.forename: Alwyn
authors.initials: A
authors.lastname: Jones
authors.forename: Sashin
authors.initials: S
authors.lastname: Ahuja
authors.forename: Kathleen
authors.initials: K
authors.lastname: Lyons
mesh_terms: D000082:Acetaminophen / Q000627:therapeutic use; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D001416:Back Pain / Q000188:drug therapy / Q000209:etiology; D001706:Biopsy; D002648:Child; D002908:Chronic Disease / Q000628:therapy; D005260:Female; D006801:Humans; D007249:Inflammation / Q000188:drug therapy / Q000209:etiology; D008159:Lumbar Vertebrae / Q000000981:diagnostic imaging / Q000473:pathology / Q000503:physiopathology; D008279:Magnetic Resonance Imaging; D010019:Osteomyelitis / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology*; D012008:Recurrence; D012600:Scoliosis / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology*; D013131:Spine / Q000000981:diagnostic imaging / Q000473:pathology* / Q000503:physiopathology; D013904:Thoracic Vertebrae / Q000000981:diagnostic imaging / Q000473:pathology / Q000503:physiopathology; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D000082:Acetaminophen