title: Male osteoporosis with vertebral fractures? Look for ankylosing spondylitis! A report of 10 cases.
abstract: OBJECTIVE
  Several authors have described the association of ankylosing spondylitis (AS) and osteoporosis. Usually vertebral fractures complicate severe AS.
  
  
  METHODS
  We report a series of 10 men in whom benign spondyloarthropathy was discovered during etiological investigation for osteoporosis. Eight patients had B27+ AS and 2 had psoriatic arthritis with axial involvement. The mean number of vertebral fractures was 1.5. No patient had an appendicular fracture.
  
  
  RESULTS
  Phosphorus and calcium levels and measurements of 25OHD3, parathyroid hormone, osteocalcin, and serum CTX were in the normal range. The decrease in bone mineral density was greater in the spine (mean T-score at L2-L4 -2.95, mean total hip T-score -1.67).
  
  
  CONCLUSIONS
  Osteoporosis with fractures may reveal benign spondyloarthropathy whose clinical expression is sometimes incomplete. Our findings demonstrate that osteoporosis is not always correlated with the severity of AS.
authors.affiliation: Service de Rhumatologie, CHU Rangueil, 1 Avenue Jean Poulhès, Toulouse, France. laroche.m@chu-toulouse.fr
authors.forename: Michel
authors.initials: M
authors.lastname: Laroche
authors.forename: Slim
authors.initials: S
authors.lastname: Lassoued
authors.forename: Thierry
authors.initials: T
authors.lastname: Billey
authors.forename: Jacques
authors.initials: J
authors.lastname: Bernard
authors.forename: Bernard
authors.initials: B
authors.lastname: Mazi
mesh_terms: D000328:Adult; D000368:Aged; D015535:Arthritis, Psoriatic / Q000150:complications / Q000175:diagnosis; D015796:HLA-B27 Antigen; D006801:Humans; D008297:Male; D008875:Middle Aged; D010024:Osteoporosis / Q000209:etiology*; D016103:Spinal Fractures / Q000209:etiology*; D013167:Spondylitis, Ankylosing / Q000150:complications* / Q000175:diagnosis* / Q000276:immunology
chemical_list: D015796:HLA-B27 Antigen