A case report of myocardial infarction in young patient with a parental history of premature cardiovascular death: combination of prothrombotic gene mutations.
We report a case of myocardial infarction at a young age in a subject heterozygous for the G20210A prothrombin gene variant and homozygous for the C677T MTHFR polymorphism, who presented a strong family history of atherothrombosis. Genetic screening for inherited thrombophilia, especially in the presence of a strong familiarity, may be a critical information for secondary prevention of arterial thrombosis.
Botto
Nicoletta
N
Mariani
Massimiliano
M
Manfredi
Samantha
S
Andreassi
Maria Grazia
MG
D002318:Cardiovascular Diseases / Q000235:genetics*; D006801:Humans; D008487:Medical History Taking; D009154:Mutation; D009203:Myocardial Infarction / Q000235:genetics*; D010290:Parents; D013927:Thrombosis / Q000235:genetics*