title: A temporal frequency-dependent functional architecture in human V1 revealed by high-resolution fMRI.
abstract: Although cortical neurons with similar functional properties often cluster together in a columnar organization, only ocular dominance columns, the columnar structure representing segregated anatomical input (from one of the two eyes), have been found in human primary visual cortex (V1). It has yet to be shown whether other columnar organizations that arise only from differential responses to stimulus properties also exist in human V1. Using high-resolution functional magnetic resonance imaging, we have found such a functional architecture containing domains that respond preferentially to either low or high temporal frequency.
authors.affiliation: Laboratory for Cognitive Brain Mapping, RIKEN Brain Science Institute, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan. psun@brain.riken.jp
authors.forename: Pei
authors.initials: P
authors.lastname: Sun
authors.forename: Kenichi
authors.initials: K
authors.lastname: Ueno
authors.forename: R Allen
authors.initials: RA
authors.lastname: Waggoner
authors.forename: Justin L
authors.initials: JL
authors.lastname: Gardner
authors.forename: Keiji
authors.initials: K
authors.lastname: Tanaka
authors.forename: Kang
authors.initials: K
authors.lastname: Cheng
mesh_terms: D001931:Brain Mapping; D007839:Functional Laterality / Q000502:physiology*; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008279:Magnetic Resonance Imaging; D009949:Orientation / Q000502:physiology*; D010100:Oxygen / Q000097:blood; D010775:Photic Stimulation; D014793:Visual Cortex / Q000098:blood supply* / Q000502:physiology; D014795:Visual Pathways / Q000098:blood supply* / Q000502:physiology
chemical_list: D010100:Oxygen