Biologically stable 2-5A analogues containing 3'-O,4'-C-bridged adenosine as potent RNase L agonists.
Morita
Koji
K
Exploratory Chemistry Research Laboratories, Sankyo Co., Ltd.,Tokyo 140-8710, Japan.
Kaneko
Masakatsu
M
Obika
Satoshi
S
Imanishi
Takeshi
T
Kitade
Yukio
Y
Koizumi
Makoto
M
D000227:Adenine Nucleotides / Q000737:chemistry / Q000494:pharmacology*; D000241:Adenosine / Q000737:chemistry*; D004722:Endoribonucleases / Q000187:drug effects* / Q000378:metabolism; D004789:Enzyme Activation; D009843:Oligoribonucleotides / Q000737:chemistry / Q000494:pharmacology*
D000227:Adenine Nucleotides; D009843:Oligoribonucleotides; C023505:2',5'-oligoadenylate; D004722:Endoribonucleases; C031956:2-5A-dependent ribonuclease; D000241:Adenosine