title: Efficacy of combination therapy for the management regime of Alopecia areata.
abstract: Alopecia areata is a world wide cosmetic problem. Cases are seen in Bangladesh. Due to financial constraint and lack of modern facilities the patients of this country needs cheap, easily available and conveniently usable treatment modality. The present study revealed that the oral administration of prednisolone for 06 weeks followed by topical application of 02% minoxidil for another period of 14 weeks is noninvasive and could act as better remedy for alopecia areata. It is claimed that steroid could induce hair growth through immunosuppression rather than a direct effect on hair growth promotion. When applied together steroid it induced regrowing hair gave more encouraging result. The combination therapy indicated that the gradual loss of hair could be minimized and regrowth of hair could be made possible. To fulfill the demand for the best compliance of treatment modality further study should be directed and dictated amongst a large group of population.
authors.affiliation: Department of Dermatology and Venereology, Combined Military Hospital, Dhaka, Bangladesh.
authors.forename: M M
authors.initials: MM
authors.lastname: Chowdhury
authors.forename: M H
authors.initials: MH
authors.lastname: Rahman
authors.forename: M A
authors.initials: MA
authors.lastname: Wahab
mesh_terms: D000328:Adult; D000506:Alopecia Areata / Q000188:drug therapy*; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use*; D001459:Bangladesh; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D008297:Male; D008914:Minoxidil / Q000627:therapeutic use; D011239:Prednisolone / Q000627:therapeutic use*; D016896:Treatment Outcome
chemical_list: D000893:Anti-Inflammatory Agents; D007166:Immunosuppressive Agents; D008914:Minoxidil; D011239:Prednisolone