title: A case of celiac disease mimicking amyotrophic lateral sclerosis.
abstract: BACKGROUND
  A 44-year-old male presented to a general neurology clinic with a 6-month history of progressive right-sided spastic hemiparesis without sensory symptoms or signs. The thigh muscle in the affected leg showed signs of wasting. The patient had a remote family history of celiac disease.
  
  
  METHODS
  Neurological examination, neurophysiological studies, brain MRI scan, routine blood tests, duodenal biopsy, cerebrospinal fluid analysis including polymerase chain reaction test for JC virus DNA, serological testing for HIV and for the presence of serum antibodies to endomysium, gliadin and tissue transglutaminase.
  
  
  METHODS
  Celiac disease with neurological involvement, mimicking amyotrophic lateral sclerosis.
  
  
  RESULTS
  Strict gluten-free diet.
authors.affiliation: Department of Neurology, John Radcliffe Hospital, Oxford, UK.
authors.forename: Martin R
authors.initials: MR
authors.lastname: Turner
authors.forename: Gurjit
authors.initials: G
authors.lastname: Chohan
authors.forename: Gerardine
authors.initials: G
authors.lastname: Quaghebeur
authors.forename: Richard C D
authors.initials: RC
authors.lastname: Greenhall
authors.forename: Marios
authors.initials: M
authors.lastname: Hadjivassiliou
authors.forename: Kevin
authors.initials: K
authors.lastname: Talbot
mesh_terms: D000328:Adult; D000690:Amyotrophic Lateral Sclerosis / Q000175:diagnosis*; D001921:Brain / Q000473:pathology; D002446:Celiac Disease / Q000097:blood / Q000134:cerebrospinal fluid / Q000175:diagnosis* / Q000178:diet therapy; D018753:Diet, Protein-Restricted; D005983:Glutens; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009460:Neurologic Examination / Q000379:methods; D012680:Sensitivity and Specificity; D012698:Serologic Tests
chemical_list: D005983:Glutens