title: Product deuterium isotope effect for orotidine 5'-monophosphate decarboxylase: evidence for the existence of a short-lived carbanion intermediate.
authors.affiliation: Department of Chemistry, University at Buffalo, Buffalo, New York 14260, USA.
authors.forename: Krisztina
authors.initials: K
authors.lastname: Toth
authors.forename: Tina L
authors.initials: TL
authors.lastname: Amyes
authors.forename: Bryant M
authors.initials: BM
authors.lastname: Wood
authors.forename: Kui
authors.initials: K
authors.lastname: Chan
authors.forename: John A
authors.initials: JA
authors.lastname: Gerlt
authors.forename: John P
authors.initials: JP
authors.lastname: Richard
mesh_terms: D002244:Carbon / Q000737:chemistry*; D003903:Deuterium; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D009964:Orotidine-5'-Phosphate Decarboxylase / Q000737:chemistry* / Q000378:metabolism*; D014542:Uridine Monophosphate / Q000031:analogs & derivatives / Q000737:chemistry / Q000378:metabolism
chemical_list: C005417:orotidylic acid; D002244:Carbon; D003903:Deuterium; D014542:Uridine Monophosphate; D009964:Orotidine-5'-Phosphate Decarboxylase