title: Evidence-based medicine: vacuum-assisted closure in wound care management.
abstract: A review of the evidence base for the use of vacuum-assisted closure (VAC) therapy is presented, analysing both experimental and clinical data.
authors.affiliation: Department of Plastic and Reconstructive Surgery, Queen Victoria Hospital, East Grinstead, West Sussex, RH19 3DZ, UK. drjudehunter@hotmail.com
authors.forename: Judith E
authors.initials: JE
authors.lastname: Hunter
authors.forename: Luc
authors.initials: L
authors.lastname: Teot
authors.forename: Raymond
authors.initials: R
authors.lastname: Horch
authors.forename: Paul E
authors.initials: PE
authors.lastname: Banwell
mesh_terms: D016207:Cytokines / Q000302:isolation & purification; D004487:Edema / Q000628:therapy; D019317:Evidence-Based Medicine; D006085:Graft Survival; D006097:Granulation Tissue / Q000378:metabolism; D006801:Humans; D010447:Peptide Hydrolases / Q000302:isolation & purification; D012039:Regional Blood Flow; D012867:Skin / Q000098:blood supply; D016038:Skin Transplantation; D013396:Suction / Q000191:economics; D014618:Vacuum; D014945:Wound Healing; D014947:Wounds and Injuries / Q000628:therapy*
chemical_list: D016207:Cytokines; D010447:Peptide Hydrolases