[Participation of muscarinic and nicotinic cholinoreceptors of hypothalamus preoptic area in control of wakefulness and sleep states and of thermoregulation in pigeons Columbia livia].
By using electrophysiological methods, it has been established that muscarinic (M-) cholinergic mechanisms of the ventrolateral preoptic area (VLPA) of pigeon hypothalamus participate in maintenance of wakefulness, whereas nicotinic (N-) mechanisms--in maintenance of the slow-wave sleep. Activation of the VLPA M-cholinergic receptors has been found to be accompanied by an elevation of the brain temperature, by development of peripheral vasoconstriction, and by an increase in the muscle contractive activity. Activation of N-cholinoreceptors leads to a decrease in the brain temperature and development of peripheral vasoconstriction. It is suggested that the VLPA M- and N-cholinergic receptors are involved in different mechanisms of regulation of wakefulness and sleep states and brain temperature in pigeons.
Komarova
T G
TG
Ekimova
I V
IV
Pastukhov
Iu F
IuF
D000818:Animals; D001833:Body Temperature Regulation / Q000502:physiology*; D010856:Columbidae / Q000502:physiology*; D009119:Muscle Contraction / Q000502:physiology; D011301:Preoptic Area / Q000098:blood supply / Q000502:physiology*; D011976:Receptors, Muscarinic / Q000378:metabolism*; D011978:Receptors, Nicotinic / Q000378:metabolism*; D012890:Sleep / Q000502:physiology*; D014661:Vasoconstriction / Q000502:physiology; D014851:Wakefulness / Q000502:physiology*
D011976:Receptors, Muscarinic; D011978:Receptors, Nicotinic