title: [Coagulopathy resulting from lupus anticoagulant antibodies as a paraneoplastic phenomenon in renal cell carcinoma relapse].
abstract: Lupus anticoagulant syndrome (LAS) is a form of coagulopathy with protracted PTT and an elevated risk of thromboembolic events, which occasionally occurs as a paraneoplastic phenomen in the presence of tumors. It is diagnosed by specific coagulation tests that identify lupus anticoagulant antibodies. We present the case of a 57-year-old woman with a coagulopathy caused by lupus anticoagulant antibodies as a paraneoplastic phenomenon in the course of a relapse of clear cell renal cell carcinoma in the area of the ipsilateral adrenal gland 18 months after tumor nephrectomy. After adrenalectomy with concomitant administration of low-molecular-weight heparin the PTT became normal and the diagnostic tests for lupus anticoagulant antibodies became negative.
authors.affiliation: Klinik für Urologie, Evangelisches Krankenhaus Johannesstift, Bielefeld, Deutschland. Navid.Berdjis@hotmail.com
authors.forename: N
authors.initials: N
authors.lastname: Berdjis
authors.forename: M
authors.initials: M
authors.lastname: Meier
authors.forename: F
authors.initials: F
authors.lastname: Hoeppner
authors.forename: H
authors.initials: H
authors.lastname: Behrendt
mesh_terms: D002292:Carcinoma, Renal Cell / Q000175:diagnosis / Q000209:etiology*; D003937:Diagnosis, Differential; D004211:Disseminated Intravascular Coagulation / Q000097:blood / Q000150:complications* / Q000175:diagnosis*; D005260:Female; D006801:Humans; D007680:Kidney Neoplasms / Q000175:diagnosis* / Q000209:etiology*; D016682:Lupus Coagulation Inhibitor / Q000097:blood*; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis / Q000209:etiology*; D010257:Paraneoplastic Syndromes / Q000150:complications* / Q000175:diagnosis
chemical_list: D016682:Lupus Coagulation Inhibitor