title: Cavitary disease and quantitative sputum bacillary load in cases of pulmonary tuberculosis.
abstract: We examined sputum bacterial loads in adults with newly diagnosed tuberculosis using quantitative culture and time-until-positive (DTP) culture in BACTEC 460. Patients with cavitary disease had higher CFU levels than those without cavities and shorter DTPs. Within radiographic strata of moderately and far advanced tuberculosis, higher CFU counts were associated with cavitary disease.
authors.affiliation: Núcleo de Doenças Infecciosas-Centro de Ciências da Saúde, Universidade Federal do Espírito Santo, Av Marechal Campos, 1468 Maruipe, Vitória, Brazil. mpalaci@ndi.ufes.br
authors.forename: Moises
authors.initials: M
authors.lastname: Palaci
authors.forename: Reynaldo
authors.initials: R
authors.lastname: Dietze
authors.forename: David Jamil
authors.initials: DJ
authors.lastname: Hadad
authors.forename: Fabiola Karla Corrêa
authors.initials: FK
authors.lastname: Ribeiro
authors.forename: Renata Lyrio
authors.initials: RL
authors.lastname: Peres
authors.forename: Solange Alves
authors.initials: SA
authors.lastname: Vinhas
authors.forename: Ethel Leonor Noia
authors.initials: EL
authors.lastname: Maciel
authors.forename: Valdério
authors.initials: V
authors.lastname: do Valle Dettoni
authors.forename: Libby
authors.initials: L
authors.lastname: Horter
authors.forename: W Henry
authors.initials: WH
authors.lastname: Boom
authors.forename: John L
authors.initials: JL
authors.lastname: Johnson
authors.forename: Kathleen D
authors.initials: KD
authors.lastname: Eisenach
mesh_terms: D000293:Adolescent; D000328:Adult; D015169:Colony Count, Microbial; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009169:Mycobacterium tuberculosis / Q000302:isolation & purification*; D013183:Sputum / Q000382:microbiology*; D014397:Tuberculosis, Pulmonary / Q000382:microbiology* / Q000473:pathology*