HIV-related mortality among tuberculosis patients in The Netherlands, 1993-2001.
Human immunodeficiency virus (HIV) infection in tuberculosis (TB) patients in The Netherlands during the period 1993-2001 was associated with an increased risk of death (adjusted odds ratio 4.71, P < 0.002). Age and sex-standardised mortality rates among HIV-infected TB patients decreased significantly over time, from 22.9% in 1993-1995 to 11.8% in 1999-2001 (P < 0.001). No such change was observed for HIV-negative patients. The decrease in mortality is likely due to the more widespread use of highly active antiretroviral therapy (HAART).
Haar
C H
CH
KNCV Tuberculosis Foundation, The Hague, The Netherlands.
Cobelens
F G J
FG
Kalisvaart
N A
NA
van Gerven
P J H J
PJ
van der Have
J J
JJ
D017088:AIDS-Related Opportunistic Infections / Q000401:mortality*; D000293:Adolescent; D000328:Adult; D023241:Antiretroviral Therapy, Highly Active; D002648:Child; D005260:Female; D006678:HIV / Q000302:isolation & purification; D015658:HIV Infections / Q000188:drug therapy / Q000401:mortality*; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D009026:Mortality / Q000639:trends; D009426:Netherlands / Q000453:epidemiology; D012307:Risk Factors; D014376:Tuberculosis / Q000150:complications / Q000401:mortality*