title: Nicotine dependence mediates the relations between insomnia and both panic and posttraumatic stress disorder in the NCS-R sample.
abstract: Although a growing literature has demonstrated elevations in insomnia symptoms among persons with either panic disorder (PD) or posttraumatic stress disorder (PTSD) relative to people without psychopathology, comparably little is known about processes underlying these associations. In recognition of this important gap in the literature, this study tested nicotine dependence as a partial mediator of the relations between insomnia symptoms and both PD and PTSD among a nationally representative sample of 5,692 (3,311 females; M(age)=43.33, SD=16.55) adults from the National Comorbidity Survey-Replication. Consistent with hypotheses, nicotine dependence partially mediated the relations between insomnia and both PD and PTSD after controlling for variance accounted for by diagnoses of major depressive episodes, drug and alcohol dependence, and gender. Overall, results suggest nicotine dependence may be a possible mechanism that underlies insomnia among those with PD and PTSD.
authors.affiliation: Department of Psychology, Intervention Science Laboratory, University of Arkansas, Fayetteville, Arkansas 72701, USA. kbabson@uark.edu
authors.forename: Kimberly A
authors.initials: KA
authors.lastname: Babson
authors.forename: Matthew T
authors.initials: MT
authors.lastname: Feldner
authors.forename: Natalie
authors.initials: N
authors.lastname: Sachs-Ericsson
authors.forename: Norman B
authors.initials: NB
authors.lastname: Schmidt
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Zvolensky
mesh_terms: D000328:Adult; D000428:Alcohol Drinking / Q000453:epidemiology; D015897:Comorbidity; D005260:Female; D006801:Humans; D008297:Male; D016584:Panic Disorder / Q000175:diagnosis / Q000453:epidemiology*; D015995:Prevalence; D007319:Sleep Initiation and Maintenance Disorders / Q000453:epidemiology*; D013313:Stress Disorders, Post-Traumatic / Q000175:diagnosis / Q000453:epidemiology*; D014029:Tobacco Use Disorder / Q000453:epidemiology*