Xeniaphyllane-derived terpenoids from the formosan soft coral Sinularia gibberosa.
New xeniaphyllane-derived metabolites (1-7) were isolated from the EtOAc extract of the Formosan soft coral Sinularia gibberosa. The structures and relative configurations of these compounds were elucidated on the basis of extensive spectroscopic analysis (including 2D NMR) and by comparison of their spectral data with those of related compounds. In vitro cytotoxic evaluation of the above metabolites towards a limited panel of cancer cell lines is also described.
Chen
Shin-Pin
SP
Department of Marine Biotechnology and Resources, National Sun Yat-sen University, Kaoshiung 804, Taiwan, R.O.C.
Su
Jui-Hsin
JH
Ahmed
Atallah Fouad
AF
Dai
Chang-Feng
CF
Wu
Yang-Chang
YC
Sheu
Jyh-Horng
JH
D000085:Acetates / Q000737:chemistry; D000818:Animals; D037421:Anthozoa / Q000737:chemistry*; D000970:Antineoplastic Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D045744:Cell Line, Tumor; D004354:Drug Screening Assays, Antitumor; D006801:Humans; D020128:Inhibitory Concentration 50; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D012717:Sesquiterpenes / Q000737:chemistry*; D013729:Terpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
D000085:Acetates; D000970:Antineoplastic Agents; D012717:Sesquiterpenes; D013729:Terpenes; C007650:ethyl acetate