title: Quetiapine for elderly non-responsive schizophrenia patients.
abstract: Ten elderly chronic schizophrenia patients who were not responding to an atypical antipsychotic were switched to quetiapine. The Brief Psychiatric Rating Scale (BPRS) demonstrated statistically significant improvement after 6 months of quetiapine treatment. Four patients discontinued treatment due to clinical exacerbation or sedation. There was no increase in abnormal movements or body weight.
authors.affiliation: Abarbanel Mental Health Center, Tel-Aviv University, Israel.
authors.forename: Doron
authors.initials: D
authors.lastname: Mazeh
authors.forename: Diana
authors.initials: D
authors.lastname: Paleacu
authors.forename: Yoram
authors.initials: Y
authors.lastname: Barak
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D014150:Antipsychotic Agents / Q000627:therapeutic use*; D010054:Brief Psychiatric Rating Scale; D003987:Dibenzothiazepines / Q000627:therapeutic use*; D004351:Drug Resistance; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D000069348:Quetiapine Fumarate; D012559:Schizophrenia / Q000188:drug therapy*
chemical_list: D014150:Antipsychotic Agents; D003987:Dibenzothiazepines; D000069348:Quetiapine Fumarate