[Endoscopic lesions in the upper digestive tract in patients with terminal chronic renal insufficiency].
BACKGROUND
End Stage Renal Disease (ESRD) causes changes that affect every organ system including the digestive tract. These changes are manifested by a variety of symptoms and are responsible for a high degree of morbidity and mortality. The main objective of this study is to determine the most common endoscopic lesions of the upper gastrointestinal tract seen in patients with a diagnosis of ESRD.


METHODS
This is a descriptive and retrospective study that included patients (age > 18 yrs.) with a known diagnosis of ESRD. The study was done at Hospital Central FAP - Hemodialysis Program from January, 2000 to February, 2007. Patients had an esophagogastroduodenoscopy (EGD) during that period of time. We conducted a chart review to evaluate medical history, demographics and EGD results.


RESULTS
The study included 54 patients with a diagnosis of ESRD; mean age was 73.2 years and the male to female ratio was 1.45:1. The average time from diagnosis was 32 months and the mean blood urea nitrogen and creatinine were 94.4 and 3.9 mg/dL respectively. Symptoms were present in 37.1% of the patients and the most common cause of endoscopic evaluation was upper gastrointestinal bleed (29.6%). The most prevalent endoscopic findings included gastric erosions (35.2%), patchy antral erythema (27.8%), gastric ulcer (24.1%), and duodenal erosions (18.5%). The most common histopathologic diagnosis was superficial chronic gastritis (65.8%). Helicobacter pylori was found in 38.6% of the studied individuals.


CONCLUSIONS
The most common endoscopic changes seen in patients with ESRD were gastric erosions, patchy antral erythema, gastric ulcers, and duodenal erosions.
Chacaltana
Alfonso
A
Médico Gastroenterólogo Ex Residente de Gastroenterología del Hospital Central, FAP
Velarde
Héctor
H
Espinoza
Julio
J
D000368:Aged; D000369:Aged, 80 and over; D003430:Cross-Sectional Studies; D004378:Duodenal Diseases / Q000150:complications / Q000175:diagnosis*; D004384:Duodenoscopy; D004935:Esophageal Diseases / Q000150:complications / Q000175:diagnosis*; D004945:Esophagoscopy; D005260:Female; D005773:Gastroscopy; D006801:Humans; D008297:Male; D008875:Middle Aged; D051436:Renal Insufficiency, Chronic / Q000150:complications*; D012189:Retrospective Studies; D013272:Stomach Diseases / Q000150:complications / Q000175:diagnosis*