title: Hair coloring systems delivering color with reduced fiber damage.
abstract: The possible metal-induced formation of free radical species such as the hydroxyl radical (HO*) during the use of permanent hair coloring products has been demonstrated. These highly reactive species are formed from the reaction of hydrogen peroxide with redox metals such as copper, which are thought to be absorbed by the hair from the from-the-tap wash water. Formation of such radical species has been shown to lead to measurable keratin fiber damage. The incorporation of chelants such as N,N'-ethylenediamine disuccinic acid (EDDS) has been demonstrated to prevent this metal-induced radical formation and thus significantly reduce the fiber damage. This chelant is highly effective due to its ability to specifically bind low levels of copper in the presence of relatively high levels of calcium, as is found in hair.
authors.affiliation: The Procter & Gamble Company, Whitehall Lane, Surrey, UK, TW20 9NW.
authors.forename: Jennifer M
authors.initials: JM
authors.lastname: Marsh
authors.forename: Janine
authors.initials: J
authors.lastname: Flood
authors.forename: Dirk
authors.initials: D
authors.lastname: Domaschko
authors.forename: Niranjan
authors.initials: N
authors.lastname: Ramji
mesh_terms: D006197:Hair; D006200:Hair Color; D006801:Humans; D017665:Hydroxyl Radical; D008855:Microscopy, Electron, Scanning; D010084:Oxidation-Reduction; D017550:Spectroscopy, Fourier Transform Infrared
chemical_list: D017665:Hydroxyl Radical