title: Conformational equilibria of ethanolamine and its hydrochloride in solution.
abstract: The conformational preferences of ethanolamine and its hydrochloride in solution were estimated by comparing experimental NMR vicinal proton-proton coupling constants to semiemprical coupling constants for each staggered rotamer, derived by the Haasnoot-Altona method. Strong gauche preferences are observed for both ethanolamine and its hydrochloride over a wide range of solvent polarities. Concentration was not observed to significantly affect the position of the conformer equilibria.
authors.affiliation: Gates and Crellin Laboratories of Chemistry, California Institute of Technology, Pasadena, California 91125, USA.
authors.forename: Tim D
authors.initials: TD
authors.lastname: Smith
authors.forename: James B
authors.initials: JB
authors.lastname: Gerken
authors.forename: Parag V
authors.initials: PV
authors.lastname: Jog
authors.forename: John D
authors.initials: JD
authors.lastname: Roberts
mesh_terms: D019856:Ethanolamine / Q000737:chemistry*; D015394:Molecular Structure; D012996:Solutions / Q000737:chemistry
chemical_list: D012996:Solutions; D019856:Ethanolamine