title: Early goal directed therapy for sepsis during pregnancy.
abstract: Sepsis is a leading cause of death in pregnancy and results in significant perinatal mortality. These deaths occur despite the younger age of pregnant patients, the low rate of comorbid conditions and the potential for effective interventions that should result in rapid resolution of illness. To date, no "evidence-based" recommendations are specific to the pregnant patient who is critically ill or septic. Optimal care for the septic patient requires a multidisciplinary team with expertise in obstetrics, maternal-fetal medicine, critical care, infectious disease, anesthesia, and pharmacy. Coordination of care and good communication amongst team members is essential. Incorporation of early goal directed therapy for suspected sepsis into obstetric practice is needed to optimize maternal and neonatal outcomes.
authors.affiliation: Northwest Perinatal Center, 9701 SW Barnes Road, Suite 299, Portland, OR 97225, USA. dguinn@whallc.com
authors.forename: Debra A
authors.initials: DA
authors.lastname: Guinn
authors.forename: David E
authors.initials: DE
authors.lastname: Abel
authors.forename: Mark W
authors.initials: MW
authors.lastname: Tomlinson
mesh_terms: D001794:Blood Pressure / Q000502:physiology; D005260:Female; D006801:Humans; D010043:Outcome and Process Assessment, Health Care; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000209:etiology / Q000503:physiopathology / Q000628:therapy*; D012307:Risk Factors; D018805:Sepsis / Q000209:etiology / Q000503:physiopathology / Q000628:therapy*