[Effectiveness and tolerance of duodenoscopic bowel preparation for colonoscopy].
OBJECTIVE
Bowel preparation for colonoscopy remains an unpleasant experience because oral solutions have unpleasant tastes and may provoke abdominal pain, nausea, vomiting, and sleep disturbance. Duodenoscopic bowel preparation is an alternative method for patients who are unwilling to take oral preparation solution or for those who are supposed to have both gastroscopic and colonoscopic examination on the same day. We assessed the effectiveness and tolerance of duodenoscopic bowel preparation.


METHODS
Patients in group OA (orally administered) ingested 45 mL of sodium phosphate (NaP) in the evening before the day of procedure and in the morning on the day of colonoscopy, whereas patients in group EA (endoscopically administered) were prepared for the procedure by duodenoscopic infusion of 90 mL of NaP diluted with 180 mL of water into the second portion of the duodenum. After 4 hours, we assessed the overall quality of colonic cleansing, using a range of excellent to inadequate. The patients completed a questionnaire on their preparation-associated symptoms, tolerance, and preference.


RESULTS
In group EA, sleep disturbance (p0.05) and nausea (p0.05) occurred less frequently than in group OA. Overall, the tolerance rating for preparation was higher in group EA. However, the quality of colonic cleansing and cecum intubation time was not different between the two groups. Patients in group EA who had ingested NaP in the past preferred duodenoscopic bowel preparation.


CONCLUSIONS
Duodenoscopic bowel preparation may play a role in colonic cleansing especially for patients who are scheduled to undergo gastroscopic and colonoscopic examination on the same day and for those who are unwilling to ingest NaP.
Maeng
Ju Hee
JH
Department of Internal Medicine, Digestive Disease Center, Institute for Digestive Research, Soon Chun Hyang University College of Medicine, Seoul and Bucheon, Korea.
Ko
Bong Min
BM
Lee
Moon Sung
MS
Na
Hyun Sik
HS
Yoon
Hyo Joong
HJ
Han
Sang Hun
SH
Kim
Sang Gyune
SG
Hong
Su Jin
SJ
Ryu
Chang Beom
CB
Kim
Young Seok
YS
Moon
Jong Ho
JH
Kim
Jin Oh
JO
Cho
Joo Young
JY
Lee
Joon Seong
JS
Shim
Chan Sup
CS
Kim
Boo Sung
BS
D000284:Administration, Oral; D000328:Adult; D000368:Aged; D002400:Cathartics / Q000008:administration & dosage* / Q000009:adverse effects; D003113:Colonoscopy; D004384:Duodenoscopy; D005260:Female; D006801:Humans; D007089:Image Enhancement; D008297:Male; D008875:Middle Aged; D010710:Phosphates / Q000008:administration & dosage* / Q000009:adverse effects / Q000737:chemistry; D011795:Surveys and Questionnaires; D007507:Therapeutic Irrigation; D016896:Treatment Outcome
D002400:Cathartics; D010710:Phosphates; C018279:sodium phosphate