title: Efficacy of radical surgery in preventing early local recurrence and cavity-related complications in hydatic liver disease.
abstract: BACKGROUND
  Hydatic disease of the liver remains to be a complex worldwide problem especially in rural areas. Early local recurrence and cavity-related complications are still a matter of conflict in the management of hydatic liver disease. The aim of this study is to investigate efficacy of the type of surgical treatment in preventing early local recurrence and cavity-related complications of this disease. Here, we present the preliminary results of our study.
  
  
  METHODS
  This study was performed prospectively including 32 patients who were operated for hydatic liver disease between January 2001 and January 2005. Patients were randomized into radical and conservative surgery groups. Recurrences at the primary surgical site in the first 2 years were considered as early local recurrence and biliary leakage, biliary fistula, cavity abscess, etc. were considered as cavity-related complications.
  
  
  RESULTS
  Early local recurrences were observed only after conservative surgical procedures (p=0.045). Recurrent cysts were found to be due to satellite cysts or pericystic disease. Cavity-related complications were seen in six patients in the conservative surgery group (p=0.011).
  
  
  CONCLUSIONS
  In suitable patients, radical surgical resection provides an effective surgical management option in preventing early local recurrence and cavity-related complications when compared to conservative surgical approaches.
authors.affiliation: Department of Surgery, Hepato-Pancreato-Biliary Surgery Unit, Gazi University Medical School Beşevler, 06500, Ankara, Turkey. osmanyuksel1971@yahoo.com.tr
authors.forename: Osman
authors.initials: O
authors.lastname: Yüksel
authors.forename: Nusret
authors.initials: N
authors.lastname: Akyürek
authors.forename: Tolga
authors.initials: T
authors.lastname: Sahin
authors.forename: Bülent
authors.initials: B
authors.lastname: Salman
authors.forename: Cem
authors.initials: C
authors.lastname: Azili
authors.forename: Hasan
authors.initials: H
authors.lastname: Bostanci
mesh_terms: D000328:Adult; D000368:Aged; D015766:Albendazole / Q000627:therapeutic use; D000871:Anthelmintics / Q000627:therapeutic use; D004444:Echinococcosis, Hepatic / Q000150:complications / Q000601:surgery*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000517:prevention & control*; D011446:Prospective Studies; D013997:Time Factors
chemical_list: D000871:Anthelmintics; D015766:Albendazole