Hodgkin's lymphoma: the role of radiation in the modern combined strategies of treatment.
A history of the treatment of Hodgkin's disease with radiation therapy and chemotherapy is presented. Studies are reviewed examining treatment for favorable and unfavorable presentation of stage I-II disease, stage III-IV disease, and relapsed disease. In this era of combined-modality therapy we have reached the point of near-total conquest of Hodgkin's lymphoma, but challenges remain. Directions for future research are discussed.
Hoppe
Richard T
RT
Department of Radiation Oncology, Stanford University, 875 Blake Wilbur Drive, Room CC-G224, Stanford, CA 94305, USA. rhoppe@stanford.edu
D003131:Combined Modality Therapy; D004307:Dose-Response Relationship, Radiation; D049673:History, 20th Century; D049674:History, 21st Century; D006689:Hodgkin Disease / Q000188:drug therapy / Q000532:radiotherapy*; D006801:Humans; D015182:Lymphatic Irradiation / Q000266:history / Q000379:methods*; D009367:Neoplasm Staging; D016032:Randomized Controlled Trials as Topic