title: Stereoselective total synthesis of bistramide A.
abstract: A highly stereoselective and convergent total synthesis of bistramide A is described. The salient feature of this synthesis is the construction of the spiroketal subunit by hydrolysis of dialkylated tosylmethyl isocyanide derivative derived via alkylation of TosMIC with suitably substituted halohydrin derivatives.
authors.affiliation: Organic Chemistry Division-I, Indian Institute of Chemical Technology, Hyderabad 500007, India. yadavpub@iict.res.in
authors.forename: J S
authors.initials: JS
authors.lastname: Yadav
authors.forename: Lakshindra
authors.initials: L
authors.lastname: Chetia
mesh_terms: D000081:Acetamides / Q000138:chemical synthesis*; D000818:Animals; D015394:Molecular Structure; D011714:Pyrans / Q000138:chemical synthesis*; D013141:Spiro Compounds / Q000138:chemical synthesis; D014561:Urochordata / Q000737:chemistry
chemical_list: D000081:Acetamides; D011714:Pyrans; D013141:Spiro Compounds; C059975:bistratene A