title: Spatial resolution enhancement using sensitivity-encoded echo-planar imaging at 3T in a typical motor paradigm.
abstract: We employ a single-shot sensitivity-encoded (SENSE) gradient-echo EPI acquisition in order to enhance spatial resolution in a typical motor fMRI experiment at 3T. Functional time series were acquired with an acquisition matrix size of 56x192 within a readout time of 82 ms, yielding an effective in-plane resolution of 0.94 mmx0.94 mm and compared to a conventional acquisition. Our data suggest that fMRI can readily be performed with a spatial resolution adapted to detailed cortical functional topography. However, in all potential applications the specific behavior of spatial specificity and statistical sensitivity needs to be taken into account.
authors.affiliation: Institute for Biomedical Engineering, University of Zurich and Swiss Federal Institute of Technology Zurich, Switzerland. conny_schmidt@sbic.a-star.edu.sg
authors.forename: Conny F
authors.initials: CF
authors.lastname: Schmidt
authors.forename: Klaas P
authors.initials: KP
authors.lastname: Pruessmann
authors.forename: Peter
authors.initials: P
authors.lastname: Boesiger
mesh_terms: D000328:Adult; D017352:Echo-Planar Imaging / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D012680:Sensitivity and Specificity