Effects of mental practice embedded in daily therapy compared to therapy as usual in adult stroke patients in Dutch nursing homes: design of a randomised controlled trial.
BACKGROUND
Mental practice as an additional cognitive therapy is getting increased attention in stroke rehabilitation. A systematic review shows some evidence that several techniques in which movements are rehearsed mentally might be effective but not enough to be certain. This trial investigates whether mental practice can contribute to a quicker and/or better recovery of stroke in two Dutch nursing homes. The objective is to investigate the therapeutic potential of mental practice embedded in daily therapy to improve individually chosen daily activities of adult stroke patients compared to therapy as usual. In addition, we will investigate prognostic variables and feasibility (process evaluation).


METHODS
A randomised, controlled, observer masked prospective trial will be conducted with adult stroke patients in the (sub)acute phase of stroke recovery. Over a six weeks intervention period the control group will receive multi professional therapy as usual. Patients in the experimental group will be instructed how to perform mental practice, and will receive care as usual in which mental practice is embedded in physical, occupation and speech therapy sessions. Outcome will be assessed at six weeks and six months. The primary outcome measure is the patient-perceived effect on performance of daily activities as assessed by an 11-point Likert Scale. Secondary outcomes are: Motricity Index, Nine Hole Peg Test, Barthel Index, Timed up and Go, 10 metres walking test, Rivermead Mobility Index. A sample size of the patients group and all therapists will be interviewed on their opinion of the experimental program to assess feasibility. All patients are asked to keep a log to determine unguided training intensity.


CONCLUSIONS
Advantages and disadvantages of several aspects of the chosen design are discussed.


BACKGROUND
ISRCTN27582267.
Braun
Susy M
SM
The centre of expertise in life sciences, Zuyd University, Heerlen, The Netherlands. s.braun@hszuyd.nl
Beurskens
Anna J
AJ
van Kroonenburgh
Susanne M
SM
Demarteau
Jeroen
J
Schols
Jos M
JM
Wade
Derick T
DT
D000203:Activities of Daily Living; D000328:Adult; D015928:Cognitive Behavioral Therapy; D004311:Double-Blind Method; D004569:Electroencephalography; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D015337:Multicenter Studies as Topic; D015999:Multivariate Analysis; D009426:Netherlands / Q000453:epidemiology; D009483:Neuropsychological Tests; D009735:Nursing Homes; D017063:Outcome Assessment, Health Care; D011446:Prospective Studies; D012044:Regression Analysis; D012720:Severity of Illness Index; D000071939:Stroke Rehabilitation; D013997:Time Factors