title: Anaplastic ganglioglioma in a middle-aged woman: a case report with a review of the literature.
abstract: We report a case of anaplastic ganglioglioma. A 45-yr-old woman was admitted with a 5-month history of headache and dizziness, both of which progressed slowly. Preoperative magnetic resonance imaging revealed a strong enhancing mass in the left frontal lobe extending to the cingulate gyrus. Adjuvant radiation therapy and chemotherapy were given after gross total resection of the tumor. Histological and immunohistochemical studies showed an anaplastic ganglioglioma. Gangliogliomas of the central nervous system are rather uncommon tumors, and anaplastic ones are extremely rare. The pertinent literature regarding gangliogliomas is reviewed.
authors.affiliation: Department of Neurosurgery, Institute of Health Science, Gyeongsang National University School of Medicine, Jinju, Korea.
authors.forename: Dong Ho
authors.initials: DH
authors.lastname: Kang
authors.forename: Chul Hee
authors.initials: CH
authors.lastname: Lee
authors.forename: Soo Hyun
authors.initials: SH
authors.lastname: Hwang
authors.forename: In Sung
authors.initials: IS
authors.lastname: Park
authors.forename: Jong Woo
authors.initials: JW
authors.lastname: Han
authors.forename: Jin Myung
authors.initials: JM
authors.lastname: Jung
mesh_terms: D000708:Anaplasia / Q000473:pathology; D001932:Brain Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D017024:Chemotherapy, Adjuvant; D005260:Female; D005625:Frontal Lobe / Q000473:pathology; D018303:Ganglioglioma / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D006179:Gyrus Cinguli / Q000473:pathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D018714:Radiotherapy, Adjuvant