title: Treatment of immobilization hypercalciuria using weekly alendronate in two quadriplegic patients.
abstract: Metabolic and urinary problems encountered in spinal cord injury patients are multifaced. We report two patients with high-level spinal cord injuries who have developed hypercalciuria after admission to the rehabilitation unit. To establish a clean intermittent self-catheterization programme, the hypercalciuria was treated successfully with alendronate. Twenty-four-hour urinary calcium excretion decreased significantly after medical treatment for hypercalciuria. Since high-level quadriplegic patients may not be mobilized in the acute phase of the rehabilitation, use of alendronate for preventing hypercalciuria and maintaining a successful clean intermittent self-catheterization programme can be considered as a supportive/complementary measure.
authors.affiliation: Department of Physical Medicine and Rehabilitation, Faculty of Medicine, Baskent University, 5. Sokak No: 48, Bahcelievler, Ankara 06490, Turkey. atalayayce@hotmail.com
authors.forename: Ayce
authors.initials: A
authors.lastname: Atalay
authors.forename: Nur
authors.initials: N
authors.lastname: Turhan
mesh_terms: D000328:Adult; D019386:Alendronate / Q000008:administration & dosage*; D050071:Bone Density Conservation Agents / Q000008:administration & dosage*; D006801:Humans; D053565:Hypercalciuria / Q000188:drug therapy* / Q000209:etiology*; D007103:Immobilization / Q000009:adverse effects*; D008297:Male; D011782:Quadriplegia / Q000150:complications; D013119:Spinal Cord Injuries / Q000150:complications* / Q000628:therapy
chemical_list: D050071:Bone Density Conservation Agents; D019386:Alendronate