title: Efficient use of the iron ortho-nitrophenylporphyrin chloride to mimic biological oxidations of dimethylaminoantipyrine.
abstract: Major metabolites of dimethylaminoantipyrine have been synthesized using iron ortho-nitrophenylporphyrin chloride as biomimetic catalyst. Reactivity of iron tetrakis-ortho-nitrophenylporphyrin chloride [Fe(TNO2PP)Cl] has been compared with iron tetrakis-pentafluorophenylporphyrin chloride and iron tetrakis-2,6-dichlorophenylporphyrin chloride using various oxidants such as hydrogen peroxide, iodosobenzene, and cumene hydroperoxide in either protic or aprotic solvent. Effect of imidazole has been showed on the reactivity of Fe(TNO2PP)Cl/cumene hydroperoxide system.
authors.forename: Marc J
authors.initials: MJ
authors.lastname: Bazin
authors.forename: Helen
authors.initials: H
authors.lastname: Shi
authors.forename: Jeannine
authors.initials: J
authors.lastname: Delaney
authors.forename: Billie
authors.initials: B
authors.lastname: Kline
authors.forename: Zhendong
authors.initials: Z
authors.lastname: Zhu
authors.forename: Cyrille
authors.initials: C
authors.lastname: Kuhn
authors.forename: Francoise
authors.initials: F
authors.lastname: Berlioz
authors.forename: Kathleen A
authors.initials: KA
authors.lastname: Farley
authors.forename: Gwen
authors.initials: G
authors.lastname: Fate
authors.forename: Wing
authors.initials: W
authors.lastname: Lam
authors.forename: Gregory S
authors.initials: GS
authors.lastname: Walker
authors.forename: Linning
authors.initials: L
authors.lastname: Yu
authors.forename: Michael P
authors.initials: MP
authors.lastname: Pollastri
mesh_terms: D000632:Aminopyrine / Q000737:chemistry* / Q000378:metabolism; D002712:Chlorides / Q000737:chemistry*; D006861:Hydrogen Peroxide / Q000737:chemistry; D007501:Iron / Q000737:chemistry*; D008665:Metalloporphyrins / Q000737:chemistry*; D015394:Molecular Structure; D016877:Oxidants / Q000737:chemistry; D010084:Oxidation-Reduction
chemical_list: D002712:Chlorides; D008665:Metalloporphyrins; D016877:Oxidants; D000632:Aminopyrine; D006861:Hydrogen Peroxide; D007501:Iron