title: Detection of coronary stenoses in chronic stable angina by multi-detector CT coronary angiography.
abstract: OBJECTIVE
  To assess the accuracy for detection of coronary stenoses in chronic stable angina patients.
  
  
  METHODS
  Twenty-four chronic stable angina patients, referred for conventional coronary angiography by the indication of positive stress tests or clinical highly suspicion of coronary artery disease were enrolled. MDCT coronary angiography (MDCTCA) and conventional coronary angiography (144 coronary vessels) were performed within one month. Accuracy of MDCTCA for predicting significant coronary artery stenoses was analyzed.
  
  
  RESULTS
  Five patients were excluded due to the total Agaston calcium score more than 500. Therefore, 114 vessels or 209 segments from 19 patients (9 males and 10 females) were available for analysis, and 186 segments were assessable (89%). Of all assessable segments, 13 from 20 significant lesions (65%) and 158 from 167 normal or non-significant lesions (95%) were correctly detected by MDCTCA. The sensitivity, specificity, positive and negative predictive values to detect significant coronary artery stenoses in terms of vessel are 82%, 96%, 79%, and 97% respectively.
  
  
  CONCLUSIONS
  Coronary CT angiography provides accurate assessment of coronary luminal artery narrowing and shows the ability to exclude significant coronary artery stenoses in patients with chronic stable angina.
authors.affiliation: Department of Radiology, Faculty of Medicine, Chulalongkorn University, Bangkok 10330, Thailand.
authors.forename: Melissa
authors.initials: M
authors.lastname: Panmethis
authors.forename: Somjai
authors.initials: S
authors.lastname: Wangsuphachart
authors.forename: Pairoj
authors.initials: P
authors.lastname: Rerkpattanapipat
authors.forename: Suphot
authors.initials: S
authors.lastname: Srimahachota
authors.forename: Wacin
authors.initials: W
authors.lastname: Buddhari
authors.forename: Weeranuch
authors.initials: W
authors.lastname: Kitsukjit
mesh_terms: D000787:Angina Pectoris / Q000150:complications*; D002908:Chronic Disease; D017023:Coronary Angiography; D023921:Coronary Stenosis / Q000150:complications / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D008297:Male; D011237:Predictive Value of Tests; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed