title: Large periampullary villous tumor of the duodenum.
abstract: A 67-year-old woman, who had symptoms of epigastric pain and abdominal distension, was found, on endoscopy, to have a large sessile villous adenoma of the periampullary duodenum. Despite the lack of evidence of malignancy, a pancreaticoduodenectomy procedure was performed, mainly because of the tumor size and site, involving the ampulla of Vater. The presence of the carcinoma was diagnosed only in the resected specimen by definitive histology. Because there is no general consensus on the optimal surgical procedure for the treatment of villous tumors of the duodenum, especially for the early stages, the indications for the operative procedure are discussed, based on a review of the literature.
authors.affiliation: Surgical Unit A, Department of Surgery, Second Faculty of Medicine, University of Rome "La Sapienza", Rome, Italy.
authors.forename: Marco
authors.initials: M
authors.lastname: Cavallini
authors.forename: Daniele
authors.initials: D
authors.lastname: Cavaniglia
authors.forename: Francesco
authors.initials: F
authors.lastname: Felicioni
authors.forename: Valeria
authors.initials: V
authors.lastname: Vitale
authors.forename: Emanuela
authors.initials: E
authors.lastname: Pilozzi
authors.forename: Vincenzo
authors.initials: V
authors.lastname: Ziparo
mesh_terms: D018253:Adenoma, Villous / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D000368:Aged; D014670:Ampulla of Vater / Q000000981:diagnostic imaging / Q000473:pathology; D004379:Duodenal Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D005260:Female; D006801:Humans; D016577:Pancreaticoduodenectomy / Q000379:methods*; D011859:Radiography