[Acute renal failure after videolaparoscopic surgery: an avoidable complication?].
Videolaparoscopic surgery exposes the abdominal organs to the mechanical effect of pneumoperitoneum at pressure values between 12 and 15 mm Hg, which are considered safe. Nevertheless, experimental data have shown that this pressure range can represent a hemodynamic risk factor as it may induce a decrease in the venous return to the right ventricle, a decrease in cardiac output, and activation of the sympathetic nervous system and renin angiotensin system. We report two cases of acute renal failure that occurred soon after videolaparoscopy in young female patients without any evidence of ongoing renal disease. Patient A was 29 years old and was submitted to videolaparoscopic surgery in a follow-up program after surgical treatment of ovarian cancer; patient B was 15 years old and was submitted to the surgical removal of a monolateral ovarian cyst. In neither of the cases was it necessary to perform hemodialysis. Patient A underwent a renal biopsy under ultrasound guidance; optic microscopy showed only in ra- and extraglomerular capillary congestion. In both cases the acute renal failure resolved completely and the patients where discharged with normal renal function. Taking in to account that normal renal venous pressure levels are around 4 mmHg we think that a) a 15 mmHg pneumoperitoneum may represent a risk factor during videolaparoscopic surgery mainly if the patient's extracellular volume is not properly expanded; b) administration of nonsteroidal anti-inflammatory drugs in order to prevent surgical pain may inhibit vasodilatory prostaglandin availability; c) onset of oliguria during the surgical procedure suggests that extracellular volume expansion is required.
Allaria
P M
PM
UO Nefrologia e Dialisi, Azienda Ospedaliera, Ospedale di Circolo, Busto Arsizio (VA), Italy. pallaria@aobusto.it
Lucatello
A
A
Battaglia
C
C
Gandini
E
E
D'Amato
I
I
Brambilla P Soni
I
I
Castiglioni
A
A
Caligara
F
F
Torpia
R
R
Molinari
A
A
Giangrande
A
A
D058186:Acute Kidney Injury / Q000209:etiology* / Q000628:therapy; D000293:Adolescent; D000328:Adult; D005260:Female; D005440:Fluid Therapy / Q000379:methods; D006801:Humans; D010535:Laparoscopy / Q000009:adverse effects*; D010048:Ovarian Cysts / Q000601:surgery; D010051:Ovarian Neoplasms / Q000601:surgery; D011027:Pneumoperitoneum / Q000150:complications; D012075:Remission, Spontaneous; D012307:Risk Factors; D016896:Treatment Outcome; D020535:Video-Assisted Surgery / Q000009:adverse effects*