[Comparative evaluation of the informative value of the rapid serochek mbt test to determine mycobacterium tuberculosis antibodies and mantoux tuberculin test in adults].
The diagnostic informative value of the Serochek MBT test (Zephyr Biomedicals, India) in detecting serum Mycobacterium tuberculosis antibodies was compared with that of the Mantoux tuberculin test with 2 TE of PPD-L in patients with pulmonary tuberculosis. The informative value of the study rapid method for the diagnosis of tuberculosis was generally 1.8 times less than that of the Mantoux tuberculin test with 2 TE of PPD-L (only intensive and hyperergic tuberculin tests were kept in mind): 6.1 times less in patients with small forms; 1.4 times less in the examinees with disseminated processes; 1.5 times greater than in chronic pulmonary tuberculosis. Since the detection and diagnosis of tuberculosis are very important at an early development stage of the disease, the findings (9% positive serotests in small forms of pulmonary tuberculosis) suggest the low sensitivity of the approved Serochek MBT test in verifying the presence of serum Mycobacterium tuberculosis antibodies and therefore its low informative value as a method to be used for the rapid diagnosis of tuberculosis.
Platonova
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Sakhelashvili
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MI
D000328:Adult; D000907:Antibodies, Bacterial / Q000032:analysis*; D006801:Humans; D009169:Mycobacterium tuberculosis / Q000276:immunology*; D011237:Predictive Value of Tests; D014374:Tuberculin Test / Q000379:methods*; D014397:Tuberculosis, Pulmonary / Q000175:diagnosis* / Q000382:microbiology
D000907:Antibodies, Bacterial