Matrix metalloproteinases in infants with posthemorrhagic hydrocephalus.
The cerebrospinal fluid matrix metalloproteinase (MMP) activities were measured in infants with posthemorrhagic hydrocephalus to elucidate the intrinsic mechanism for the resolution of ventricular dilation. Increased MMP-9 activities were observed in the patients who escaped a shunt operation, suggesting its potential contribution to the resolution of ventricular dilation.
Okamoto
Toshio
T
Department of Pediatrics, Asahikawa Medical College, Asahikawa Kosei Hospital, Hokkaido 078-8510, Japan. toshio5p@asahikawa-med.ac.jp
Takahashi
Satoru
S
Nakamura
Eiki
E
Nagaya
Ken
K
Hayashi
Tokitsugi
T
Shirai
Masaru
M
Fujieda
Kenji
K
D004591:Electrophoresis, Polyacrylamide Gel; D006801:Humans; D006849:Hydrocephalus / Q000134:cerebrospinal fluid / Q000201:enzymology*; D007231:Infant, Newborn; D020778:Matrix Metalloproteinase 2 / Q000134:cerebrospinal fluid*; D020780:Matrix Metalloproteinase 9 / Q000134:cerebrospinal fluid*
D020778:Matrix Metalloproteinase 2; D020780:Matrix Metalloproteinase 9