title: Clinical parameters in T1N0M0 lower lip squamous cell carcinoma.
abstract: This retrospective study was carried out to asses the clinical outcome of T1 (i.e., tumor 2 cm or less at greatest dimension) squamous cell carcinoma of the lower lip (SCCLL) and verify the impact of some clinical parameters on prognosis. Fifty-seven patients with histologically proven T1 SCCLL were analyzed. Fifty-two patients were never treated before admission, whereas five (8.8%) had a second radical resection of the primary tumor location; none had neck nodes (i.e., N0) or distant metastasis (i.e., M0). The global disease-specific survival rate at 32 months was 100%, irrespective of grading and type of surgery, and thus no differences were statistically detected. Therefore, we concluded that radical tumor resection is a viable procedure for T1 SCCLL, irrespectively of grading. In addition, a second surgery on the primary tumor location is possible and has effectiveness on survival. Finally, neck dissection is not necessary in cases of T1 SCCLL.
authors.affiliation: Department of Plastic Surgery, Ospedale S. Orsola, Bologna, Italy.
authors.forename: Paolo
authors.initials: P
authors.lastname: Morselli
authors.forename: Loredana
authors.initials: L
authors.lastname: Masciotra
authors.forename: Valentina
authors.initials: V
authors.lastname: Pinto
authors.forename: Ilaria
authors.initials: I
authors.lastname: Zollino
authors.forename: Giorgio
authors.initials: G
authors.lastname: Brunelli
authors.forename: Francesco
authors.initials: F
authors.lastname: Carinci
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002294:Carcinoma, Squamous Cell / Q000145:classification / Q000401:mortality / Q000601:surgery*; D004812:Epidemiologic Methods; D005260:Female; D006801:Humans; D008048:Lip Neoplasms / Q000145:classification / Q000401:mortality / Q000601:surgery*; D008297:Male; D008875:Middle Aged