Pharmaceutical applications for catanionic mixtures.
Mixtures of oppositely charged surfactants, so called catanionic mixtures, are a growing area of research. These mixtures have been shown to form several different types of surfactant aggregates, such as micelles of various forms and sizes, and lamellar structures, such as vesicles. In this review, a short introduction to the field of catanionic mixtures is presented and the pharmaceutical possibilities offered by such mixtures are reviewed. There are several interesting ideas on how to apply catanionic mixtures to improve the delivery of, for example, drug compounds and DNA, or for HIV treatment.
Bramer
Tobias
T
Department of Pharmacy, Uppsala University, Box 580, SE-751 23 Uppsala, Sweden.
Dew
Noel
N
Edsman
Katarina
K
D000838:Anions / Q000737:chemistry; D019380:Anti-HIV Agents / Q000737:chemistry; D002412:Cations / Q000737:chemistry; D002626:Chemistry, Pharmaceutical; D004247:DNA / Q000737:chemistry; D004337:Drug Carriers; D004364:Pharmaceutical Preparations / Q000737:chemistry*; D013501:Surface-Active Agents / Q000737:chemistry*
D000838:Anions; D019380:Anti-HIV Agents; D002412:Cations; D004337:Drug Carriers; D004364:Pharmaceutical Preparations; D013501:Surface-Active Agents; D004247:DNA