Melioidosis: a review of orthopedic manifestations, clinical features, diagnosis and management.
Melioidosis is an infectious disease caused by gram-negative soil-dwelling bacillus Burkholderia pseudomallei. Musculoskeletal melioidosis mimics other infections both clinically and radiologically. An extensive literature review has been performed over musculoskeletal melioidosis through various search engines such as Pubmed, Embase, Medscape, Altavista and Google. Diagnosis requires a high index of clinical suspicion and is dependent on microbiological confirmation. Prompt treatment with long-term combination antibiotics in high dosages and surgical drainage of abscesses improves survival.
Jain
Vijay Kumar
VK
Department of Orthopedics, Dr. RML Hospital, New Delhi, India. drvijay_ortho@yahoo.com
Jain
Deepali
D
Kataria
Himanshu
H
Shukla
Ajay
A
Arya
Rajendra Kumar
RK
Mittal
Deepak
D
D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D016957:Burkholderia pseudomallei / Q000187:drug effects*; D002442:Ceftazidime; D004318:Doxycycline; D004359:Drug Therapy, Combination; D006801:Humans; D008554:Melioidosis / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology; D009140:Musculoskeletal Diseases / Q000382:microbiology; D012307:Risk Factors; D016896:Treatment Outcome
D000900:Anti-Bacterial Agents; D002442:Ceftazidime; D004318:Doxycycline