Quality of life after extratemporal epilepsy surgery: a prospective clinical study.
OBJECTIVE
The purpose of this prospective clinical study was to assess quality of life (QOL) and impact of seizure status on QOL in patients with extratemporal epilepsy after surgery.


METHODS
Twenty-three consecutive patients who had been operated due to extratemporal epilepsy were included in this study. Quality of Life Inventory in Epilepsy-10 (QOLIE-10) questionnaire was completed by all patients before 6 months and 2 years after surgery. Results obtained from short- and long-term follow-up were compared to baseline. Furthermore, patients who were seizure-free since surgery and those who had seizure were also compared in terms of outcome in QOL after surgery.


RESULTS
All patients showed significantly improved QOL in both short- and long-term follow-ups compared to preoperative status regardless of seizure status (p<0.001). Seizure-free patients showed better QOL than those of patients who continued to have seizure during postoperative period. Furthermore, improved QOL was correlated with seizure status and shorter duration of epilepsy (p=0.001).


CONCLUSIONS
Our findings showed that improved QOL is related to postoperative seizure status. However, future clinical studies including larger population of patients with extratemporal epilepsy are required to elucidate the role of other factors.
Tanriverdi
Taner
T
Department of Neurosurgery, Montreal Neurological Institute and Hospital, McGill University, Montreal, Quebec, Canada. tanerato2000@yahoo.com
Olivier
Nicole Poulin
NP
Olivier
Andre
A
D000328:Adult; D000927:Anticonvulsants / Q000627:therapeutic use; D018572:Disease-Free Survival; D004351:Drug Resistance; D004827:Epilepsy / Q000188:drug therapy / Q000523:psychology / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D011446:Prospective Studies; D011788:Quality of Life; D012959:Socioeconomic Factors; D013997:Time Factors; D016896:Treatment Outcome
D000927:Anticonvulsants