title: Violacein: properties and biological activities.
abstract: The violet pigment violacein is an indole derivative, isolated mainly from bacteria of the genus Chromobacterium, which exhibits important antitumoral, antimicrobial and antiparasitary properties. Furthermore, the formulation of violacein in different polymeric carriers developed so far offers alternative approaches to overcoming physiological barriers and undesirable physicochemical properties in vivo, thus improving its efficacy.
authors.affiliation: Laboratório de Quimica Biológica, Instituto de Química, Universidade Estadual de Campinas (UNICAMP), C.P. 6154, CEP 13083-970, Campinas, SP, Brazil. duran@iqm.unicamp.br
authors.forename: Nelson
authors.initials: N
authors.lastname: Durán
authors.forename: Giselle Z
authors.initials: GZ
authors.lastname: Justo
authors.forename: Carmen V
authors.initials: CV
authors.lastname: Ferreira
authors.forename: Patrícia S
authors.initials: PS
authors.lastname: Melo
authors.forename: Livia
authors.initials: L
authors.lastname: Cordi
authors.forename: Dorival
authors.initials: D
authors.lastname: Martins
mesh_terms: D000890:Anti-Infective Agents / Q000009:adverse effects / Q000737:chemistry* / Q000494:pharmacology*; D000970:Antineoplastic Agents / Q000009:adverse effects / Q000737:chemistry* / Q000494:pharmacology*; D002861:Chromobacterium / Q000737:chemistry; D006801:Humans; D007211:Indoles / Q000009:adverse effects / Q000737:chemistry* / Q000494:pharmacology*
chemical_list: D000890:Anti-Infective Agents; D000970:Antineoplastic Agents; D007211:Indoles; C063155:violacein