Solvent-controlled Csp2-->O silyl migration: the "one-pot" synthesis of 2,3-disubsituted thiophenes.
An effective "one-pot" synthesis of disubstituted thiophene derivatives employing 3-bromo-2-silyl thiophenes has been developed. A solvent-controlled [1,4] Csp2-->O silyl migration was involved as the key step in this process.
Devarie-Baez
Nelmi O
NO
Department of Chemistry, Washington State University, Pullman, Washington 99164, USA.
Shuhler
Brian J
BJ
Wang
Hua
H
Xian
Ming
M