title: PharmARTS: terminology web services for drug safety data coding and retrieval.
abstract: MedDRA and WHO-ART are the terminologies used to encode drug safety reports. The standardisation achieved with these terminologies facilitates: 1) The sharing of safety databases; 2) Data mining for the continuous reassessment of benefit-risk ratio at national or international level or in the pharmaceutical industry. There is some debate about the capacity of these terminologies for retrieving case reports related to similar medical conditions. We have developed a resource that allows grouping similar medical conditions more effectively than WHO-ART and MedDRA. We describe here a software tool facilitating the use of this terminological resource thanks to an RDF framework with support for RDF Schema inferencing and querying. This tool eases coding and data retrieval in drug safety.
authors.affiliation: INSERM, UMRS_872 Eq20, Paris, F-75006 France. Iulian.Alecu@spim.jussieu.fr
authors.forename: Iulian
authors.initials: I
authors.lastname: Alecu
authors.forename: Cédric
authors.initials: C
authors.lastname: Bousquet
authors.forename: Patrice
authors.initials: P
authors.lastname: Degoulet
authors.forename: Marie-Christine
authors.initials: MC
authors.lastname: Jaulent
mesh_terms: D016907:Adverse Drug Reaction Reporting Systems; D064420:Drug-Related Side Effects and Adverse Reactions / Q000145:classification*; D006801:Humans; D016247:Information Storage and Retrieval; D007256:Information Systems; D012984:Software; D039061:Systematized Nomenclature of Medicine; D009626:Terminology as Topic; D014584:User-Computer Interface; D018875:Vocabulary, Controlled