title: Analysis of HumFABP2 as a polymorphic human genetic marker in the Turkish population.
abstract: OBJECTIVE
  To examine the allele frequencies of HumFABP2 locus in 155 individuals from different regions of Turkey.
  
  
  METHODS
  The study was carried out in Cumhuriyet University Hospital, Sivas, Turkey, between March and June 2006. The allele and genotype frequencies for HumFABP2 were determined by polymerase chain reaction (PCR) using the manufacturer's recommended protocol, and using the commercially available Macherey-Nagel DNA isolation kit. The PCR amplification was carried out in a Perkin-Elmer GeneAmp PCR System 9600 thermal cycler following the manufacturer's recommendations. The allele frequencies in the Turkish population was computed, and the heterozygote rate was calculated.
  
  
  RESULTS
  In this population study of 155 samples, we found 75 (48.39%) heterozygote and 80 (51.61%) homozygote. The results showed heterozygotic cases as 150/250 bp, and homozygotic cases as 150 bp.
  
  
  CONCLUSIONS
  Allele frequency data of HumFABP2 as a PCR-based genetic marker could be used in identity testing to estimate the frequency of a multiple PCR based profile in the Turkish population.
authors.affiliation: Department of Forensic Medicine, Cumhuriyet University School of Medicine, Sivas, Turkey. fyucel@cumhuriyet.edu.tr
authors.forename: Fatma Y
authors.initials: FY
authors.lastname: Beyaztas
authors.forename: Ilhan
authors.initials: I
authors.lastname: Sezgin
authors.forename: Eylem
authors.initials: E
authors.lastname: Gul
authors.forename: Zerrin
authors.initials: Z
authors.lastname: Erkol
mesh_terms: D050556:Fatty Acid-Binding Proteins / Q000235:genetics*; D005260:Female; D005787:Gene Frequency; D005819:Genetic Markers / Q000235:genetics; D005838:Genotype; D006801:Humans; D008297:Male; D016133:Polymerase Chain Reaction; D011110:Polymorphism, Genetic / Q000235:genetics*; D014421:Turkey
chemical_list: C493404:FABP2 protein, human; D050556:Fatty Acid-Binding Proteins; D005819:Genetic Markers