Chirped coherent anti-Stokes Raman scattering as a high-spectral- and spatial-resolution microscopy.
Coherent anti-Stokes Raman scattering (CARS) microscopy is a promising tool for chemically selective imaging based on molecular vibrations. While CARS is currently used as a biological imaging tool, many variations are still being developed, perhaps the most important being multiplex CARS microscopy. Multiplex CARS has the advantage of comparing images based on different molecular vibrations without changing the excitation wavelengths. Here we demonstrate both high-spectral- and spatial-resolution multiplex CARS imaging of polymer films, using a simple scheme for chirped CARS with a spectral bandwidth of 300 cm(-1).
Onorato
Robert M
RM
Department of Chemistry, University of California, USA.
Muraki
Naoki
N
Knutsen
Kelly P
KP
Saykally
Richard J
RJ