title: Xeniaphyllane-derived terpenoids from the formosan soft coral Sinularia gibberosa.
abstract: New xeniaphyllane-derived metabolites (1-7) were isolated from the EtOAc extract of the Formosan soft coral Sinularia gibberosa. The structures and relative configurations of these compounds were elucidated on the basis of extensive spectroscopic analysis (including 2D NMR) and by comparison of their spectral data with those of related compounds. In vitro cytotoxic evaluation of the above metabolites towards a limited panel of cancer cell lines is also described.
authors.affiliation: Department of Marine Biotechnology and Resources, National Sun Yat-sen University, Kaoshiung 804, Taiwan, R.O.C.
authors.forename: Shin-Pin
authors.initials: SP
authors.lastname: Chen
authors.forename: Jui-Hsin
authors.initials: JH
authors.lastname: Su
authors.forename: Atallah Fouad
authors.initials: AF
authors.lastname: Ahmed
authors.forename: Chang-Feng
authors.initials: CF
authors.lastname: Dai
authors.forename: Yang-Chang
authors.initials: YC
authors.lastname: Wu
authors.forename: Jyh-Horng
authors.initials: JH
authors.lastname: Sheu
mesh_terms: D000085:Acetates / Q000737:chemistry; D000818:Animals; D037421:Anthozoa / Q000737:chemistry*; D000970:Antineoplastic Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D045744:Cell Line, Tumor; D004354:Drug Screening Assays, Antitumor; D006801:Humans; D020128:Inhibitory Concentration 50; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D012717:Sesquiterpenes / Q000737:chemistry*; D013729:Terpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
chemical_list: D000085:Acetates; D000970:Antineoplastic Agents; D012717:Sesquiterpenes; D013729:Terpenes; C007650:ethyl acetate