title: Sentinel lymph node biopsy (SLNB) in management of N0 stage T1-T2 lip cancer as a "same day" procedure.
abstract: Current management of N0 stage lip Squamous Cell Carcinoma (SCC) are prophylactic neck dissection, radiotherapy, or "watch and see" policy. The aim is the evaluation of the role of sentinel lymph node biopsy (SLNB) in their management based upon actual and not hypothetical presence of cervical lymph node (CLN) micrometastases as a same day procedure. Fourteen patients between November 2003 and August 2005 were included, nine men and five women, median age:57 years, (range 34-65 years). SLNB using preoperative lymphoscintigraphy and intra-operative localisation with patent blue and radioactive Tc(99m) Human Serum Albumin was performed. The median follow-up period was 26 months. Successful patent blue localisation in 13/14 whilst successful radio-localisation in all patients. Micrometastases were detected in 1/14 whom underwent therapeutic neck dissection. No local recurrence or regional lymph node involvement were detected. SLNB is a technically feasible and accurate approach for detection of CLN micrometastases in N0 stage lip SCC using the triple diagnostic localisation technique as a same day procedure.
authors.affiliation: Department of Plastic & Reconstructive Surgery, Cairo University Teaching Hospitals, Cairo, Egypt. heheaa73@yahoo.com
authors.forename: H H
authors.initials: HH
authors.lastname: Khalil
authors.forename: A H
authors.initials: AH
authors.lastname: Elaffandi
authors.forename: A
authors.initials: A
authors.lastname: Afifi
authors.forename: Y
authors.initials: Y
authors.lastname: Alsayed
authors.forename: T
authors.initials: T
authors.lastname: Mahboub
authors.forename: K M
authors.initials: KM
authors.lastname: El-Refaie
mesh_terms: D000328:Adult; D000368:Aged; D000556:Ambulatory Surgical Procedures; D002294:Carcinoma, Squamous Cell / Q000473:pathology / Q000601:surgery*; D004396:Coloring Agents; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008048:Lip Neoplasms / Q000473:pathology / Q000601:surgery*; D008207:Lymphatic Metastasis / Q000175:diagnosis; D008297:Male; D008875:Middle Aged; D019275:Radiopharmaceuticals; D021701:Sentinel Lymph Node Biopsy; D013671:Technetium Tc 99m Sulfur Colloid; D016896:Treatment Outcome
chemical_list: D004396:Coloring Agents; D019275:Radiopharmaceuticals; D013671:Technetium Tc 99m Sulfur Colloid