title: Model for curvature-driven pearling instability in membranes.
abstract: A phase-field model for dealing with dynamic instabilities in membranes is presented. We use it to study curvature-driven pearling instability in vesicles induced by the anchorage of amphiphilic polymers on the membrane. Within this model, we obtain the morphological changes reported in recent experiments. The formation of a homogeneous pearled structure is achieved by consequent pearling of an initial cylindrical tube from the tip. For high enough concentration of anchors, we show theoretically that the homogeneous pearled shape is energetically less favorable than an inhomogeneous one, with a large sphere connected to an array of smaller spheres.
authors.affiliation: Departament d'Estructura i Constituents de la Matèria, Facultat de Física, Universitat de Barcelona Diagonal 647, E-08028, Barcelona, Spain. campelo@ecm.ub.es
authors.forename: F
authors.initials: F
authors.lastname: Campelo
authors.forename: A
authors.initials: A
authors.lastname: Hernández-Machado
mesh_terms: D008051:Lipid Bilayers / Q000737:chemistry; D008962:Models, Theoretical; D011108:Polymers
chemical_list: D008051:Lipid Bilayers; D011108:Polymers