title: [Frontotemporal dementia].
abstract: BACKGROUND
  Among the primary degenerative dementias, frontotemporal dementia (FTD, Pick's disease) is very important along with Alzheimer's disease. The estimated prevalence is 15:100,000 in the 45- to 64-year-old population; thus, it appears that the FTD as a cause for so-called presenile dementia is nearly as common as Alzheimer's disease.
  
  
  METHODS
  The case of a 52-year-old woman is described that presented with slowly progressive lack of concentration and disturbance of memory. Furthermore, the immediate family had noticed a change in her premorbid personality. Due to additional depressive symptoms, she was misdiagnosed with depressive pseudodementia first.
  
  
  CONCLUSIONS
  Since the clinical presentation of FTD is variable and the correct classification has been uncertain for a long time, clinical diagnosis can be very difficult, so that the disease is often detected too late or remains completely misdiagnosed. On this basis, pathology, clinical aspects, diagnosis, and therapeutic options of FTD will be demonstrated according to current standards of knowledge.
authors.affiliation: Klinik für Psychiatrie und Psychotherapie, Universität zu Köln, Köln.
authors.forename: Raguna
authors.initials: R
authors.lastname: Nagy
authors.forename: Juliane
authors.initials: J
authors.lastname: Heuckmann
authors.forename: Hans-Dieter
authors.initials: HD
authors.lastname: Mennel
authors.forename: Joachim
authors.initials: J
authors.lastname: Klosterkötter
authors.forename: Jens
authors.initials: J
authors.lastname: Kuhn
mesh_terms: D001284:Atrophy; D001288:Attention; D001921:Brain / Q000473:pathology; D003131:Combined Modality Therapy; D032882:Comprehension; D003704:Dementia / Q000175:diagnosis* / Q000534:rehabilitation; D003866:Depressive Disorder / Q000175:diagnosis / Q000534:rehabilitation; D003951:Diagnostic Errors; D004292:Dominance, Cerebral / Q000502:physiology; D005260:Female; D005625:Frontal Lobe / Q000473:pathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008569:Memory Disorders / Q000175:diagnosis / Q000534:rehabilitation; D008875:Middle Aged; D009483:Neuropsychological Tests; D020774:Pick Disease of the Brain / Q000175:diagnosis* / Q000534:rehabilitation; D049268:Positron-Emission Tomography; D012050:Rehabilitation, Vocational; D013702:Temporal Lobe / Q000473:pathology