Molecular genetics of infantile-onset retinal dystrophies.
Over the last decade there have been major advances in our understanding of the molecular pathology of inherited retinal dystrophies. This paper reviews recent advances in the identification of genetic mutations underlying infantile-onset inherited retinal disorders and considers how this knowledge may lead to novel therapeutic approaches.
Moradi
P
P
Institute of Ophthalmology UCL, London, UK.
Moore
A T
AT
D003117:Color Vision Defects / Q000235:genetics; D015785:Eye Diseases, Hereditary / Q000235:genetics* / Q000628:therapy; D006801:Humans; D007223:Infant; D009154:Mutation; D009755:Night Blindness / Q000235:genetics; D012162:Retinal Degeneration / Q000235:genetics* / Q000628:therapy