[Acute pancreatitis after treatment by celecoxib].
Drug-induced pancreatitis injury due to celecoxib, a first generation Cox-2 inhibitor, has been rarely reported. We describe one case of severe pancreatitis after treatment with celecoxib for 3 months in a woman. No aetiology has been found for pancreatitis. The role of celecoxib in the etiology of colitis was considered probable. This report and a few other cases in the literature suggest to seek a pancreatitis in the event of pains abdominal when there is a catch of the cyclooxygenase-2 selective non-steroidal anti-inflammatory drug inhibitor.
Mennecier
Didier
D
Service de pathologie digestive, Hôpital d'Instruction des Armées Bégin, Saint-Mandé. didier.mennecier@hepatoweb.com
Ceppa
Franck
F
Sinayoko
Leila
L
Corberand
Damien
D
Harnois
Florence
F
Thiolet
Catherine
C
Farret
Olivier
O
D000208:Acute Disease; D000068579:Celecoxib; D016861:Cyclooxygenase Inhibitors / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008875:Middle Aged; D010195:Pancreatitis / Q000139:chemically induced*; D011720:Pyrazoles / Q000009:adverse effects*; D013449:Sulfonamides / Q000009:adverse effects*
D016861:Cyclooxygenase Inhibitors; D011720:Pyrazoles; D013449:Sulfonamides; D000068579:Celecoxib