[Malignant lymphomas in primates and the principles of their morphological diagnosis (on a baboon model of malignant lymphomas)].
114 baboons with non-Hodgkin lymphoma (NHL) were examined, by using the morphoimmunological phenotyping technique. According to the Kiel classification, 14 types of non-Hodgkin lymphomas of high and low malignancy are identified and described. These include 8 T-cell lymphomas and six B-cell NHL. Some morphoimmunological characteristics were found. The morphological cell atypia coincided with the abnormal immunotype of tumor cells. The nosological type of hemoblastosis in the baboons is characterized by the development of mainly malignant lymphomas.
Lapin
B A
BA
Iakovleva
L A
LA
Indzhiia
L V
LV
D000818:Animals; D014408:Biomarkers, Tumor / Q000032:analysis*; D007150:Immunohistochemistry; D008223:Lymphoma / Q000175:diagnosis / Q000473:pathology*; D008992:Monkey Diseases / Q000175:diagnosis / Q000473:pathology*; D010215:Papio
D014408:Biomarkers, Tumor