title: Chronic intestinal pseudo-obstruction in patients with systemic lupus erythematosus: report of four cases.
abstract: Chronic intestinal pseudo-obstruction (CIPO), a recently recognized manifestation of systemic lupus erythematosus (SLE) with only 23 cases reported in the English literature, may appear as a complication or as the initial presentation of SLE and usually occurs during the setting of an active lupus. The pathogenic mechanism in SLE is unknown. We describe four additional cases with clinical, radiological, and manometric features of CIPO. As SLE-related CIPO usually responds to treatment with high doses of corticosteroids and/or immunosuppressive and prokinetic agents, a high level of awareness of this complication is needed to avoid unnecessary surgical intervention.
authors.affiliation: Rheumatology Section, Hospital JM Cullen, Santa Fe, Argentina.
authors.forename: Federico
authors.initials: F
authors.lastname: Ceccato
authors.forename: Adrián
authors.initials: A
authors.lastname: Salas
authors.forename: Vanina
authors.initials: V
authors.lastname: Góngora
authors.forename: Santiago
authors.initials: S
authors.lastname: Ruta
authors.forename: Susana
authors.initials: S
authors.lastname: Roverano
authors.forename: Juan Carlos
authors.initials: JC
authors.lastname: Marcos
authors.forename: Mercedes
authors.initials: M
authors.lastname: Garcìa
authors.forename: Sergio
authors.initials: S
authors.lastname: Paira
mesh_terms: D000328:Adult; D000893:Anti-Inflammatory Agents / Q000009:adverse effects*; D005260:Female; D005765:Gastrointestinal Agents / Q000627:therapeutic use*; D006801:Humans; D007418:Intestinal Pseudo-Obstruction / Q000150:complications* / Q000188:drug therapy / Q000276:immunology; D008180:Lupus Erythematosus, Systemic / Q000150:complications* / Q000188:drug therapy; D008875:Middle Aged
chemical_list: D000893:Anti-Inflammatory Agents; D005765:Gastrointestinal Agents