title: MUC1 in human testis and ejaculated spermatozoa and its relationship to male fertility status.
abstract: MUC1 is a cell surface glycoprotein with a previously described antiadhesive role involved in different aspects of reproductive function. We found MUC1 expressed in male germ cell line and within the ejaculated sperm, but its presence in mature sperm does not seem to be related to male fertility. This was confirmed after analysis of results from assisted reproduction techniques with oocyte donation related with MUC1, although higher MUC1 expression is related to sperm recovery after preparation.
authors.affiliation: Fundación Instituto Valenciano de Infertilidad, Valencia, Spain. jomarco@ivi.es
authors.forename: José A
authors.initials: JA
authors.lastname: Martínez-Conejero
authors.forename: Nicolás
authors.initials: N
authors.lastname: Garrido
authors.forename: José
authors.initials: J
authors.lastname: Remohí
authors.forename: Antonio
authors.initials: A
authors.lastname: Pellicer
authors.forename: Carlos
authors.initials: C
authors.lastname: Simón
authors.forename: Marcos
authors.initials: M
authors.lastname: Meseguer
mesh_terms: D053713:Azoospermia / Q000503:physiopathology; D004542:Ejaculation; D005298:Fertility / Q000502:physiology*; D006801:Humans; D008297:Male; D018396:Mucin-1 / Q000032:analysis* / Q000502:physiology; D013094:Spermatozoa / Q000737:chemistry*; D013737:Testis / Q000737:chemistry*
chemical_list: C060192:MUC1 protein, human; D018396:Mucin-1