title: [Genetic polymorphism of twelve Y chromosomal short tandem repeat loci in Chinese Hui ethnic group].
abstract: OBJECTIVE
  To obtain the genetic polymorphism of Y chromosomal short tandem repeat (Y-STR) loci in Ningxia Hui population.
  
  
  METHODS
  Blood samples were collected from 150 unrelated healthy male individuals of Ningxia Hui ethnic group. Twelve Y-STR loci were amplified in one tube by using the PowerPlex System STR Amplification Kit, and the genotypes were determined using Genescan and Genotype software of ABI377 DNA sequencer and the frequency of alleles and haplotypes of Ningxia Hui ethnic was obtained.
  
  
  RESULTS
  Seventy-five alleles were observed at 12 Y-STR loci. The frequency ranged from 0.0067-0.7067 and the gene diversity ranged from 0.4446-0.8877. Totally 148 different haplotypes were found, which were unique in 150 males. Two haplotypes were shared by 2 males respectively. The haplotype diversity was 0.9864.
  
  
  CONCLUSIONS
  The 12 Y-STR loci are highly polymorphic in Ningxia Hui population and are suitable for genetics and forensic research.
authors.affiliation: Key Laboratory of Reproduction and Genetics in Ningxia, Department of Medical Genetics and Cell Biology, Ningxia Medical College, Yingchuan, Ningxia, 750004 PR China.
authors.forename: Yong-sheng
authors.initials: YS
authors.lastname: Zhu
authors.forename: Zheng-hao
authors.initials: ZH
authors.lastname: Huo
authors.forename: Bing
authors.initials: B
authors.lastname: Yu
authors.forename: Hong-bo
authors.initials: HB
authors.lastname: Zhang
authors.forename: Yu-jiong
authors.initials: YJ
authors.lastname: Wang
authors.forename: Wei
authors.initials: W
authors.lastname: Zhao
authors.forename: Hai-yan
authors.initials: HY
authors.lastname: Jiao
authors.forename: Jie
authors.initials: J
authors.lastname: Dang
authors.forename: Sheng-bin
authors.initials: SB
authors.lastname: Li
mesh_terms: D044466:Asian People / Q000235:genetics*; D002681:China / Q000208:ethnology; D041322:Chromosomes, Human, Y / Q000235:genetics*; D005006:Ethnicity / Q000235:genetics*; D005787:Gene Frequency; D006239:Haplotypes; D006801:Humans; D008297:Male; D018895:Microsatellite Repeats / Q000235:genetics*; D011110:Polymorphism, Genetic