title: [Streptococcus group B--association with Aerobic vaginitis and ability to human cell lines activation].
abstract: The aim of this study was to estimate: the frequency of aerobic vaginitis, susceptibility of the GBS isolated from vagina of non-pregnant women with and without cervicitis to selected antibiotics and chemotherapeutics and the proinflammatory cytokines production by HeLa, THP-I, U - 937 cells after stimulation by vaginal GBS. Our results indicated low frequency of the aerobic vaginitis -4.5% among non-pregnant young women and ability of the vaginal GBS to release proinflammatory cytokines by human cell lines in vitro.
authors.affiliation: Katedra i Zakład Mikrobiologii Lekarskiej SAM w Katowicach.
authors.forename: Małgorzata
authors.initials: M
authors.lastname: Romanik
authors.forename: Joanna
authors.initials: J
authors.lastname: Kafel
authors.forename: Teresa
authors.initials: T
authors.lastname: Lagergård
authors.forename: Gayane
authors.initials: G
authors.lastname: Martirosian
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents; D001420:Bacteria, Aerobic / Q000302:isolation & purification / Q000378:metabolism; D002478:Cells, Cultured; D018920:Coculture Techniques; D016207:Cytokines / Q000378:metabolism*; D005260:Female; D006194:Gardnerella vaginalis / Q000302:isolation & purification; D006367:HeLa Cells / Q000378:metabolism; D006801:Humans; D053583:Interleukin-1beta / Q000032:analysis; D015850:Interleukin-6 / Q000032:analysis; D016209:Interleukin-8 / Q000032:analysis; D008262:Macrophage Activation; D008297:Male; D013290:Streptococcal Infections / Q000382:microbiology*; D013292:Streptococcus agalactiae / Q000302:isolation & purification / Q000378:metabolism*; D014409:Tumor Necrosis Factor-alpha / Q000032:analysis; D020298:U937 Cells / Q000378:metabolism; D002575:Uterine Cervicitis / Q000276:immunology* / Q000382:microbiology*; D016585:Vaginosis, Bacterial / Q000382:microbiology*
chemical_list: D000900:Anti-Bacterial Agents; D016207:Cytokines; D053583:Interleukin-1beta; D015850:Interleukin-6; D016209:Interleukin-8; D014409:Tumor Necrosis Factor-alpha