[Viral infection after lung transplantation].
We experienced 3 cases of viral infections after lung transplantation. Case 1: Fifty-two-year-old male with pulmonary emphysema underwent left single lung transplantation from a cadaveric donor. Three months after transplantation he presented Epstein-Barr virus (EBV) viremia, resulting in multiple lymphadenopathy. Biopsy showed post-transplant lymphproliferative disorder, and he was treated successfully with rituximab. He is well without recurrence around 1 and a half years after treatment. Case 2: Thitry-eight-year-old male with pulmonary emphysema underwent double lung transplantation from a cadaveric donor. Four months after transplantation he showed multiple nodules in both lungs. Percutaneous biopsy showed post-transplant lymphproliferative disorder, and he was treated successfully with rituximab. He is well without recurrence more than 2 years after treatment. Case 3 : Twenty-four-year-old woman with lymphangioleiomyomatosis underwent living-related bilateral lobar lung transplantation. Three months after lung transplantation she presented cytomegalovirus viremia. Since it proved to be ganciclovir-resistant cytomegalovirus infection, she was treated with foscarnet successfully. She is well without recurrence about 2 and a half years after treatment.
Chen
Fengshi
F
Department of Thoracic Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Aoyama
A
A
Okamoto
T
T
Takahashi
A
A
Satoda
N
N
Fujinaga
T
T
Shoji
T
T
Sakai
H
H
Matsumoto
I
I
Wada
H
H
Bando
T
T
D000328:Adult; D003586:Cytomegalovirus Infections / Q000209:etiology*; D020031:Epstein-Barr Virus Infections / Q000209:etiology*; D005260:Female; D006801:Humans; D016040:Lung Transplantation; D008232:Lymphoproliferative Disorders / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications