title: Cytokinin signaling pathway.
abstract: Cytokinins are key regulators of a large number of processes in plant development, which is highly plastic and adaptive, and remarkably resilient and self-perpetuating. Cytokinin signaling involves a multistep two-component system, also called a phosphorelay signaling system. Genes encoding the central components to build the cytokinin phosphorelay system are found in diverse plant species, resulting in the establishment of a canonical model of cytokinin signaling that is likely representative and conserved in plants. The cytokinin signaling pathway can be modulated by nutrients, stress, and other hormones, and is integrated into a signaling network in both shoots and roots.
authors.affiliation: Department of Molecular Biology, Massachusetts General Hospital, and Harvard Medical School, Boston, MA 02114, USA.
authors.forename: Bruno
authors.initials: B
authors.lastname: Müller
authors.forename: Jen
authors.initials: J
authors.lastname: Sheen
mesh_terms: D003583:Cytokinins / Q000378:metabolism*; D025461:Feedback, Physiological; D018506:Gene Expression Regulation, Plant; D000071677:Histidine Kinase; D008024:Ligands; D010766:Phosphorylation; D010937:Plant Growth Regulators / Q000378:metabolism*; D018521:Plant Physiological Phenomena; D010940:Plant Proteins / Q000235:genetics / Q000378:metabolism*; D011494:Protein Kinases / Q000378:metabolism; D015398:Signal Transduction; D014157:Transcription Factors / Q000378:metabolism
chemical_list: D003583:Cytokinins; D008024:Ligands; D010937:Plant Growth Regulators; D010940:Plant Proteins; D014157:Transcription Factors; D011494:Protein Kinases; D000071677:Histidine Kinase