Neurogenesis in the cerebellum.
In the past few years, genetic fate mapping experiments have changed our vision of cerebellar development, particularly in redefining the origin of gabaergic and glutamatergic neurons of the cerebellar cortex and highlighting the precise spatio-temporal sequence of their generation. Here the authors review cerebellar neurogenesis and discuss the fate mapping studies with other new information stemming from transplantation experiments, in an effort to link the developmental potential of neural progenitor populations of the cerebellum with their spatio-temporal origin.
Carletti
Barbara
B
Department of Neuroscience and Rita Levi Montalcini Centre for Brain Repair, National Institute of Neuroscience, University of Turin, Italy. barbara.carletti@unito.it
Rossi
Ferdinando
F
D000818:Animals; D002531:Cerebellum / Q000166:cytology* / Q000254:growth & development*; D002552:Cerebral Ventricles / Q000166:cytology / Q000254:growth & development; D006801:Humans; D009474:Neurons / Q000502:physiology