title: Antiprotozoal polyacetylenes from the Tanzanian medicinal plant Cussonia zimmermannii.
abstract: From the petroleum ether extract of the root bark of Cussonia zimmermannii four polyacetylenes, 1- 4, were isolated, three of which ( 1- 3) were active against Trypanosoma brucei rhodesiense, Trypanosoma cruzi, Plasmodium falciparum, and Leishmania donovani.
authors.affiliation: Department of Chemistry, University of Basel, St. Johanns-Ring 19, CH-4056 Basel, Switzerland.
authors.forename: Martin
authors.initials: M
authors.lastname: Senn
authors.forename: Sigmund
authors.initials: S
authors.lastname: Gunzenhauser
authors.forename: Reto
authors.initials: R
authors.lastname: Brun
authors.forename: Urs
authors.initials: U
authors.lastname: Séquin
mesh_terms: D000818:Animals; D000981:Antiprotozoal Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D027481:Araliaceae / Q000737:chemistry*; D007893:Leishmania donovani / Q000187:drug effects; D015394:Molecular Structure; D010946:Plants, Medicinal / Q000737:chemistry*; D010963:Plasmodium falciparum / Q000187:drug effects; D053279:Polyynes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D013636:Tanzania; D016833:Trypanosoma brucei rhodesiense / Q000187:drug effects
chemical_list: D000981:Antiprotozoal Agents; D053279:Polyynes