Development of a French isometric strength normative database for adults using quantitative muscle testing.
OBJECTIVE
To establish a normative database for isometric strength measured by quantitative muscle testing (QMT) for a French adult population.


METHODS
Measurement of maximal voluntary isometric contraction.


METHODS
Four clinical centers involved in neuromuscular disorders.


METHODS
A total of 315 healthy adults (147 men, 168 women) ages 20 to 80 years.


METHODS
Not applicable.


METHODS
Isometric torque values of 14 muscle functions (13 bilaterally and neck).


RESULTS
This study led to the development of a French isometric strength normative database for adults measured by QMT. For each muscle function, predictive regression models using age, sex, and weight are proposed. Some methodologic issues concerning strength measurement are discussed.


CONCLUSIONS
This database can be used to compute relative deficits in muscle strength for 27 muscle functions and also to estimate composite scores for follow-up of patients either during the natural history of their disease or during a therapeutic trial.
Hogrel
Jean-Yves
JY
Institut de Myologie, GH Pitié-Salpêtrière, Paris, France. jy.hogrel@institut-myologie.org
Payan
Christine A
CA
Ollivier
Gwenn
G
Tanant
Véronique
V
Attarian
Shahram
S
Couillandre
Annabelle
A
Dupeyron
Arnaud
A
Lacomblez
Lucette
L
Doppler
Valérie
V
Meininger
Vincent
V
Tranchant
Christine
C
Pouget
Jean
J
Desnuelle
Claude
C
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016208:Databases, Factual; D005260:Female; D005602:France; D006801:Humans; D007537:Isometric Contraction; D008297:Male; D008875:Middle Aged; D053580:Muscle Strength; D018908:Muscle Weakness / Q000503:physiopathology*; D018482:Muscle, Skeletal / Q000503:physiopathology*; D020391:Muscular Dystrophy, Facioscapulohumeral / Q000503:physiopathology; D009468:Neuromuscular Diseases / Q000503:physiopathology*; D012016:Reference Values; D015203:Reproducibility of Results