Physiological similarities and differences between renal aging and chronic renal disease.
Even though there are some functional similarities between the aged kidney and the chronically damaged one, such as the reduction in glomerular filtration rate and in the sodium-water reabsorption capability, there are many physiological differences between these two groups, as is the case of erythropoietin, urea, potassium, calcium, phosphorus and magnesium renal handling. Thus, the data presented demonstrate that renal aging and chronic kidney disease constitute different clinical scenes.
Musso
Carlos G
CG
Nephrology Department, Buenos Aires Italian Hospital, Buenos Aires - Argentina. carlos.musso@hospitalitaliano.org.ar
Macías Nuñez
Juan F
JF
Oreopoulos
Dimitrios G
DG
D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000378:metabolism*; D002118:Calcium / Q000097:blood; D004921:Erythropoietin / Q000097:blood; D005919:Glomerular Filtration Rate; D006801:Humans; D007668:Kidney / Q000378:metabolism* / Q000503:physiopathology; D008274:Magnesium / Q000097:blood; D010758:Phosphorus / Q000097:blood; D011188:Potassium / Q000097:blood; D051436:Renal Insufficiency, Chronic / Q000378:metabolism* / Q000503:physiopathology; D012720:Severity of Illness Index; D014508:Urea / Q000097:blood; D014882:Water-Electrolyte Balance
D004921:Erythropoietin; D010758:Phosphorus; D014508:Urea; D008274:Magnesium; D011188:Potassium; D002118:Calcium