title: Endometrial stripe thickness and pregnancy outcome in first-trimester pregnancies with bleeding, pain or both.
abstract: OBJECTIVE
  To determine the association between endometrial stripe (ES) thickness and pregnancy outcome in women with a symptomatic first-trimester pregnancy and to determine how vaginal bleeding, pelvic pain and 1 human chorionic gonadotropin (hCG) level affect ES thickness.
  
  
  METHODS
  Data on ES thickness, serum hCG, presence of pain, characterization of vaginal bleeding and ultimate clinical outcome were collected for 576 women presenting to the emergency room.
  
  
  RESULTS
  ES was thinner with increased vaginal bleeding and associated with hCG level and pregnancy outcome. The mean ES for ectopic pregnancies (EPs) was 9.56 +/- 4.87, for intrauterine pregnancies was 12.12 +/- 6.0 and for spontaneous abortion was 10.19 +/- 6.10. Ninety-nine percent of patients with EP had an ES <21 mm, and 100% had one < or =25 mm.
  
  
  CONCLUSIONS
  There was considerable overlap in ES for the 3 pregnancy outcomes, making it a poor diagnostic test. Nevertheless, ES >21 mm in a woman with no evidence of a gestational sac excludes EP with 96% specificity. A patient with a stripe >25 mm may be expectantly managed.
authors.affiliation: Department of Obstetrics and Gynecology, University of Pennsylvania Medical Center, Philadelphia 19104, USA.
authors.forename: Beata
authors.initials: B
authors.lastname: Seeber
authors.forename: Mary
authors.initials: M
authors.lastname: Sammel
authors.forename: Lan
authors.initials: L
authors.lastname: Zhou
authors.forename: Amy
authors.initials: A
authors.lastname: Hummel
authors.forename: Kurt T
authors.initials: KT
authors.lastname: Barnhart
mesh_terms: D000033:Abortion, Threatened / Q000000981:diagnostic imaging*; D001837:Body Weights and Measures / Q000379:methods; D006063:Chorionic Gonadotropin / Q000097:blood; D004717:Endometrium / Q000033:anatomy & histology* / Q000473:pathology; D005260:Female; D006470:Hemorrhage; D006801:Humans; D017699:Pelvic Pain / Q000000981:diagnostic imaging*; D011237:Predictive Value of Tests; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000000981:diagnostic imaging*; D011256:Pregnancy Outcome; D011271:Pregnancy, Ectopic / Q000000981:diagnostic imaging*; D012189:Retrospective Studies; D014463:Ultrasonography
chemical_list: D006063:Chorionic Gonadotropin