Contribution of molecular tools for the diagnosis of endogenous pneumococcal endophthalmitis in a patient with the acquired immunodeficiency syndrome.
Confirmation of infectious endophthalmitis is a major challenge. Traditional microbial tools are frequently unsuccessful mostly due to very small fluid samples and prior use of antibiotics. Here we report the first case of Streptococcus pneumoniae endophthalmitis diagnosed by polymerase chain reaction. Molecular biology should be considered as a new tool for the diagnosis of such sequestered sites as the eye.
Chandesris
Marie-Olivia
MO
Departments of Infectious Diseases and Tropical Medicine, Necker-Enfants Malades Hospital, Paris, France. olivia.chandesris@nck.aphp.fr
Hot
Arnaud
A
Join-Lambert
Olivier
O
Loulergue
Pierre
P
Ferroni
Agnes
A
Lortholary
Olivier
O
Viard
Jean-Paul
JP
D000163:Acquired Immunodeficiency Syndrome / Q000150:complications*; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D009877:Endophthalmitis / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology*; D006801:Humans; D008875:Middle Aged; D011008:Pneumococcal Infections / Q000150:complications* / Q000175:diagnosis* / Q000188:drug therapy; D016133:Polymerase Chain Reaction
D000900:Anti-Bacterial Agents