title: Genioplasty for genioglossus muscle advancement in patients with obstructive sleep apnea-hypopnea syndrome and mandibular retrognathia.
abstract: Obstructive sleep apnea syndrome is a complex disease, which the etiology is multifactorial and incompletely understood. Surgery with genioglossus advancement is indicated in hypopharynx obstruction.
  
  
  OBJECTIVE
  evaluate the efficacy and complications of genioplasty technique for genioglossus muscle advancement in patients with obstructive sleep apnea-hypopnea syndrome (OSAHS).
  
  
  METHODS
  polysomnography, physical examination and cephalometric analysis were performed in 10 non-obese patients, who presented mild or moderate OSAHS, an apnea-hypopnea index (AHI) between 5 and 30, with hypopharynx obstruction and mandibular retrognathia.
  
  
  RESULTS
  the AHI preoperative mean of 12.4+/-4.6 decreased to a postoperative mean of 4.4+/-5.7 (p < 0,001). When 50% reduction of preoperative AHI was chosen as a parameter, its rate was 70% (7/10). Cephalometric analysis revealed an increase in the posterior airway space (PAS) in all patients, from a preoperative mean value of 7.9+/-2.3mm to a postoperative mean value of 10.8+/-2.5mm (p < 0,001).
  
  
  CONCLUSIONS
  genioplasty for genioglossus advancement seemed to reduce OSAHS signs, thus, it can be considered as an option for the surgical treatment of patients with hypopharynx obstruction. Data collected supports this surgical procedure as an option in patients with OSAHS and mandibular retrognathia.
authors.affiliation: School of Dentistry, Universidade de Santo Amaro. joaosantosjr@uol.com.br
authors.forename: João Ferreira dos
authors.initials: JF
authors.lastname: Santos Junior
authors.forename: Márcio
authors.initials: M
authors.lastname: Abrahão
authors.forename: Luiz Carlos
authors.initials: LC
authors.lastname: Gregório
authors.forename: Adriane Iurk
authors.initials: AI
authors.lastname: Zonato
authors.forename: Emne Hammoud
authors.initials: EH
authors.lastname: Gumieiro
mesh_terms: D000328:Adult; D002508:Cephalometry; D005260:Female; D006801:Humans; D008297:Male; D019186:Mandibular Advancement / Q000379:methods*; D008875:Middle Aged; D009132:Muscles / Q000601:surgery; D017286:Polysomnography; D011446:Prospective Studies; D063173:Retrognathia / Q000150:complications / Q000601:surgery*; D020181:Sleep Apnea, Obstructive / Q000209:etiology / Q000601:surgery*; D014059:Tongue / Q000601:surgery*; D016896:Treatment Outcome