Microbial metabolism. Part 8. The pyranocoumarin, decursin.
Microbial transformation of the cancer chemopreventive agent, decursin (1) with Sepedonium chrysospermem (ATCC 13378) yielded two metabolites, (+)-decursinol (2) and (-)-cis-decursidinol (3). The structures were established by spectroscopic data.
Herath
Wimal
W
National Center for Natural Products Research, The University of Mississippi, MS 38677, USA.
Reddy
Niranjan
N
Khan
Ikhlas Ahmad
IA
D016588:Anticarcinogenic Agents / Q000494:pharmacology*; D001578:Benzopyrans / Q000494:pharmacology*; D002087:Butyrates / Q000494:pharmacology*; D002478:Cells, Cultured; D006999:Hypocreales / Q000187:drug effects* / Q000378:metabolism; D053858:Metabolic Networks and Pathways / Q000187:drug effects* / Q000502:physiology; D039681:Pyranocoumarins / Q000494:pharmacology*; D013057:Spectrum Analysis; D013237:Stereoisomerism
D016588:Anticarcinogenic Agents; D001578:Benzopyrans; D002087:Butyrates; D039681:Pyranocoumarins; C101278:decursin