Phytochemicals from Echinacea and Hypericum: A Direct Synthesis of Isoligularone.
Reaction of trienes with α,β-unsaturated aldehydes produces bicyclic products via a tandem Diels-Alder/ene reaction. The adduct from tiglic aldehyde was converted into isoligularone by conversion to a furan followed by benzylic oxidation.
Kraus
George A
GA
Department of Chemistry, Iowa State University, Ames, IA 50011.
Bae
Jaehoon
J
Kim
Junwon
J