title: Isolation and characterization of a novel helicobacter species, "Helicobacter macacae," from rhesus monkeys with and without chronic idiopathic colitis.
abstract: Chronic idiopathic colitis is a common clinical entity in young captive rhesus monkeys. Eight isolates, cultured from five monkeys in colony 1 with endemic diarrhea and three from colony 2 without diarrhea, were grown under microaerobic conditions on selective agar and were classified by full 16S rRNA sequence, biochemical, and phenotypic analysis as a novel helicobacter, "Helicobacter macacae" (proposed name). All eight strains of H. macacae had 99.5% identical 16S rRNA sequences.
authors.affiliation: Division of Comparative Medicine, Massachusetts Institute of Technology, Cambridge, MA 02139, USA. jgfox@mit.edu
authors.forename: James G
authors.initials: JG
authors.lastname: Fox
authors.forename: Samuel R
authors.initials: SR
authors.lastname: Boutin
authors.forename: Laurence K
authors.initials: LK
authors.lastname: Handt
authors.forename: Nancy S
authors.initials: NS
authors.lastname: Taylor
authors.forename: Shilu
authors.initials: S
authors.lastname: Xu
authors.forename: Barry
authors.initials: B
authors.lastname: Rickman
authors.forename: Robert P
authors.initials: RP
authors.lastname: Marini
authors.forename: Floyd E
authors.initials: FE
authors.lastname: Dewhirst
authors.forename: Bruce J
authors.initials: BJ
authors.lastname: Paster
authors.forename: Sherri
authors.initials: S
authors.lastname: Motzel
authors.forename: Hilton J
authors.initials: HJ
authors.lastname: Klein
mesh_terms: D000818:Animals; D015373:Bacterial Typing Techniques; D003092:Colitis / Q000453:epidemiology / Q000382:microbiology / Q000662:veterinary*; D004269:DNA, Bacterial / Q000737:chemistry / Q000235:genetics; D004275:DNA, Ribosomal / Q000737:chemistry / Q000235:genetics; D003967:Diarrhea / Q000453:epidemiology / Q000382:microbiology; D019353:Endemic Diseases; D020459:Genes, rRNA; D016998:Helicobacter / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification* / Q000502:physiology; D008253:Macaca mulatta / Q000382:microbiology*; D008969:Molecular Sequence Data; D010802:Phylogeny; D012329:RNA, Bacterial / Q000235:genetics; D012336:RNA, Ribosomal, 16S / Q000235:genetics; D017422:Sequence Analysis, DNA; D012689:Sequence Homology, Nucleic Acid
chemical_list: D004269:DNA, Bacterial; D004275:DNA, Ribosomal; D012329:RNA, Bacterial; D012336:RNA, Ribosomal, 16S