Thioflavin derivatives as markers for amyloid-beta fibrils: insights into structural features important for high-affinity binding.
Leuma Yona
Rodrigue
R
Laboratoire de Chimie de Coordination, CNRS UPR 8241 associated with University Toulouse III, 205 route de Narbonne, 31077 Toulouse Cedex 4, France.
Mazères
Serge
S
Faller
Peter
P
Gras
Emmanuel
E
D000544:Alzheimer Disease / Q000175:diagnosis*; D016229:Amyloid beta-Peptides / Q000737:chemistry / Q000378:metabolism*; D052160:Benzothiazoles; D001665:Binding Sites; D015415:Biomarkers / Q000378:metabolism*; D006571:Heterocyclic Compounds / Q000737:chemistry / Q000378:metabolism; D010455:Peptides / Q000737:chemistry / Q000378:metabolism; D017434:Protein Structure, Tertiary; D013329:Structure-Activity Relationship; D013844:Thiazoles / Q000737:chemistry / Q000378:metabolism*
D016229:Amyloid beta-Peptides; D052160:Benzothiazoles; D015415:Biomarkers; D006571:Heterocyclic Compounds; D010455:Peptides; D013844:Thiazoles; C009462:thioflavin T