title: [Impact on human health of hormonal additives used in animal production].
abstract: The establishment of the impact of environmental compounds or additives with hormone-like activity on human health still requires further investigation, as well as a reexamination of biologic models and experimental methodology employed so far. In 1988, the FAO/WHO Expert Committee on Food Additives Joint with the Federal Drug Administration (FDA) considered that sexual hormone residues usually present in meat do not represent a risk for human consumption. Nevertheless, this resolution seems to be uncertain since the scientific elements employed for this statement may not be adequate. In this review the principal objections to the evidence used to establish the innocuousness of growth promoter hormones are considered.
authors.affiliation: Departamento de Biología de la Reproducción, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, México, DF.
authors.forename: Fernando
authors.initials: F
authors.lastname: Larrea
authors.forename: Mayel
authors.initials: M
authors.lastname: Chirinos
mesh_terms: D000822:Animal Husbandry / Q000379:methods; D000818:Animals; D002417:Cattle; D004343:Drug Implants; D004350:Drug Residues / Q000009:adverse effects / Q000494:pharmacology*; D004967:Estrogens / Q000008:administration & dosage / Q000009:adverse effects / Q000494:pharmacology*; D005260:Female; D005506:Food Contamination / Q000032:analysis; D012739:Gonadal Steroid Hormones / Q000008:administration & dosage / Q000009:adverse effects / Q000494:pharmacology; D006128:Growth / Q000187:drug effects; D006262:Health; D006801:Humans; D007273:Injections, Intramuscular; D008297:Male; D008452:Maximum Allowable Concentration; D008460:Meat / Q000009:adverse effects / Q000032:analysis; D011627:Puberty / Q000187:drug effects; D012098:Reproduction / Q000187:drug effects; D014944:World Health Organization
chemical_list: D004343:Drug Implants; D004967:Estrogens; D012739:Gonadal Steroid Hormones