title: [Clinical features of lung cancer HIV-infected patients].
abstract: Since HIV infection and opportunistic infections began to be treated by highly active antiretroviral therapy (HAART), the incidence of cancers, especially lung cancer increased. The clinical course of lung cancer in HIV infected patients is more aggressive, and little is known about its features or management. We retrospectively evaluated 6 cases of lung cancer with HIV infected patients in Tokyo Metropolitan Komagome Hospital. All patients were male and current smokers. Adenocarcinoma, squamous cell carcinoma and small cell carcinoma were observed in 3, 2 and 1, respectively. There were 2 cases each of clinical Stage I, IIIB, and IV were each 2 cases. The range of the CD4 cell count was 52-432/microL. HIV infection was confirmed concurrently with the diagnosis of lung cancer or complications in 5 of 6 patients. Some cases treated for both lung cancer and HIV, had a relatively good clinical course. We suggest that cancer treatment concurrently with HAART may be useful for similar cases. Further experience and study are necessary.
authors.affiliation: Department of Respiratory Medicine, Tokyo Metropolitan Komagome Hospital.
authors.forename: Tetsuro
authors.initials: T
authors.lastname: Kato
authors.forename: Ryuji
authors.initials: R
authors.lastname: Ieki
authors.forename: Erika
authors.initials: E
authors.lastname: Saito
authors.forename: Tomohiro
authors.initials: T
authors.lastname: Ot
authors.forename: Kazumi
authors.initials: K
authors.lastname: Yuasa
authors.forename: Mari
authors.initials: M
authors.lastname: Iguchi
authors.forename: Tatsuru
authors.initials: T
authors.lastname: Okamura
authors.forename: Masahiko
authors.initials: M
authors.lastname: Shibuya
authors.forename: Atsushi
authors.initials: A
authors.lastname: Ajisawa
mesh_terms: D000328:Adult; D019380:Anti-HIV Agents / Q000627:therapeutic use; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D023241:Antiretroviral Therapy, Highly Active; D018791:CD4 Lymphocyte Count; D015658:HIV Infections / Q000150:complications* / Q000188:drug therapy; D006716:Homosexuality; D006801:Humans; D008175:Lung Neoplasms / Q000188:drug therapy / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D012907:Smoking
chemical_list: D019380:Anti-HIV Agents