An efficient and rapid synthetic route to biologically interesting pyranochalcone natural products.
An efficient and concise total synthesis of naturally occurring pyranochalcones was achieved from readily available 2,4-dihydroxyacetophenone and 2,4-dihydroxy-6-methoxyacetophenone. The key steps in the synthetic strategy were ethylenediamine diacetate-catalyzed benzopyran formation and aldol reactions.
Lee
Yong Rok
YR
School of Chemical Engineering and Technology, Yeungnam University, Gyeongsan 712-749, Korea. yrlee@yu.ac.kr
Wang
Xue
X
Xia
Likai
L
D001688:Biological Products / Q000138:chemical synthesis* / Q000737:chemistry*; D047188:Chalcones / Q000138:chemical synthesis* / Q000737:chemistry*; D002625:Chemistry, Organic / Q000379:methods*; D011714:Pyrans / Q000138:chemical synthesis* / Q000737:chemistry*
D001688:Biological Products; D047188:Chalcones; D011714:Pyrans