title: [Research advance of microRNA and stem cell].
abstract: OBJECTIVE
  To review the advance in the experimental studies of microRNA (miRNA) and the relationship between miRNA and stem cells.
  
  
  METHODS
  The related literature was reviewed, and the research findings of miRNA and stem cell were summarized.
  
  
  RESULTS
  miRNA was non-coding small RNA (20-25 nt) involved in post-transcriptional change, that have been shown to regulate gene expressions. It has been reported that some kinds of miRNAs were likely important regulators for stem cells maintaining their state of self-renewal, and play key roles in their differentiation.
  
  
  CONCLUSIONS
  miRNA as regulation of gene expressions, can be served as a new way for stem cells research.
authors.affiliation: Department of Orthopedic Surgery, Tangdu Hospital, Fourth Military Medical University, Xi'an Shaanxi, 710038, PR China.
authors.forename: Jie
authors.initials: J
authors.lastname: Gao
authors.forename: Tongtao
authors.initials: T
authors.lastname: Yang
authors.forename: Xiuchun
authors.initials: X
authors.lastname: Qiu
mesh_terms: D000818:Animals; D002454:Cell Differentiation; D049109:Cell Proliferation; D053595:Embryonic Stem Cells / Q000166:cytology / Q000502:physiology; D005786:Gene Expression Regulation; D006801:Humans; D051379:Mice; D035683:MicroRNAs / Q000235:genetics / Q000378:metabolism; D013234:Stem Cells / Q000166:cytology / Q000502:physiology
chemical_list: D035683:MicroRNAs