Paracoccidioidomycosis in wild monkeys from Paraná State, Brazil.
The aim of this study was to evaluate the seroprevalence of Paracoccidioides brasiliensis infection in wild New World monkeys (Cebus sp. and Alouatta caraya). A total of 93 animals (Cebus sp., n = 68 and Alouatta caraya, n = 25) were captured in the Paraná River basin, Paraná State, Brazil and the serum samples were analyzed by ELISA and immunodiffusion using P. brasiliensis gp43 and exoantigen as antigens, respectively. The seropositivity observed by ELISA was 44.1% and 60% for Cebus sp. and A. caraya, respectively, while by immunodiffusion test Cebus sp. showed positivity of 2.9% only. No significant difference was observed in relation to age and sex. This is the first report of paracoccidioidomycosis in wild capuchin monkeys and in wild-black and golden-howler monkeys. The high positivity to P. brasiliensis infection in both species evaluated in our study and the positivity by immunodiffusion test in Cebus sp. suggest that natural disease may be occurring in wild monkeys living in paracoccidioidomycosis endemic areas.
Corte
Andreia C
AC
Departamento de Ciências Patológicas, Centro de Ciências Biológicas, Universidade Estadual de Londrina, Campus Universitário, Londrina, Parana 86051990, Brazil. marioono@uel.br
Svoboda
Walfrido K
WK
Navarro
Italmar T
IT
Freire
Roberta L
RL
Malanski
Luciano S
LS
Shiozawa
M M
MM
Ludwig
Gabriela
G
Aguiar
Lucas M
LM
Passos
Fernando C
FC
Maron
Angela
A
Camargo
Zoilo P
ZP
Itano
Eiko N
EN
Ono
Mario Augusto
MA
D000508:Alouatta; D000818:Animals; D000946:Antigens, Fungal / Q000276:immunology; D001938:Brazil; D002428:Cebus; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D005656:Fungal Proteins / Q000276:immunology; D005843:Geography; D006023:Glycoproteins / Q000276:immunology; D005779:Immunodiffusion; D008297:Male; D008992:Monkey Diseases / Q000175:diagnosis* / Q000276:immunology / Q000382:microbiology; D010228:Paracoccidioides / Q000276:immunology*; D010229:Paracoccidioidomycosis / Q000175:diagnosis* / Q000276:immunology / Q000382:microbiology
C103180:43 kDa protein, Paracoccidioides; D000946:Antigens, Fungal; D005656:Fungal Proteins; D006023:Glycoproteins