title: Colonic adenocarcinoma in a 13-year-old with cystic fibrosis.
abstract: The increase in longevity among patients with cystic fibrosis has brought to light comorbidities associated with the disease that are less acutely fatal than its pulmonary manifestations. Modern retrospective analysis has demonstrated an increased risk of gastrointestinal malignancy in patients with cystic fibrosis, with a marked elevation in malignancy rates among patients in their 20s and 30s. Here we report a case of colonic adenocarcinoma presenting as pneumaturia in a 13-year-old patient with cystic fibrosis.
authors.affiliation: Division of General Surgery, Department of Surgery, University of Wisconsin Hospitals and Clinics, Madison, WI 53792, USA.
authors.forename: Anna R
authors.initials: AR
authors.lastname: Ibele
authors.forename: Stephanie A
authors.initials: SA
authors.lastname: Koplin
authors.forename: Bruce L
authors.initials: BL
authors.lastname: Slaughenhoupt
authors.forename: John V
authors.initials: JV
authors.lastname: Kryger
authors.forename: Andreas
authors.initials: A
authors.lastname: Friedl
authors.forename: Dennis P
authors.initials: DP
authors.lastname: Lund
mesh_terms: D000230:Adenocarcinoma / Q000150:complications* / Q000188:drug therapy / Q000601:surgery; D000293:Adolescent; D000388:Air; D000714:Anastomosis, Surgical; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002430:Cecal Neoplasms / Q000150:complications* / Q000000981:diagnostic imaging / Q000188:drug therapy; D003082:Colectomy; D003131:Combined Modality Therapy; D003550:Cystic Fibrosis / Q000150:complications*; D005472:Fluorouracil / Q000008:administration & dosage; D006801:Humans; D007412:Intestinal Fistula / Q000209:etiology / Q000601:surgery / Q000652:urine; D002955:Leucovorin / Q000008:administration & dosage; D008297:Male; D009944:Organoplatinum Compounds / Q000008:administration & dosage; D000077150:Oxaliplatin; D014463:Ultrasonography; D001747:Urinary Bladder Fistula / Q000209:etiology / Q000601:surgery / Q000652:urine; D014556:Urine
chemical_list: D009944:Organoplatinum Compounds; D000077150:Oxaliplatin; D002955:Leucovorin; D005472:Fluorouracil