Cutaneous reactions to drugs in children.
Cutaneous eruptions are a commonly reported adverse drug reaction. Cutaneous adverse drug reactions in the pediatric population have a significant impact on patients' current and future care options. A patient's recollection of having a "rash" when they took a medication as a child is a frequent reason for not prescribing a particular treatment. The quick detection and treatment of cutaneous adverse drug reactions, plus identification of the causative agent, are essential for preventing the progression of the reaction, preventing additional exposures, and ensuring the appropriate use of medications for both the current condition and others as the patient ages. The purpose of this review is to discuss a reasonable approach to recognition and initial management of cutaneous adverse drug reactions in children.
Segal
Alissa R
AR
Massachusetts College of Pharmacy & Health Sciences, Department of Pharmacy Practice, 179 Longwood Ave, Boston, MA 02115-5896, USA. alissa.segal@mcphs.edu
Doherty
Kevin M
KM
Leggott
John
J
Zlotoff
Barrett
B
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D016907:Adverse Drug Reaction Reporting Systems; D002648:Child; D003875:Drug Eruptions / Q000145:classification / Q000175:diagnosis* / Q000209:etiology / Q000628:therapy; D004643:Emollients / Q000627:therapeutic use; D005076:Exanthema / Q000139:chemically induced / Q000175:diagnosis / Q000628:therapy; D006634:Histamine H1 Antagonists / Q000627:therapeutic use; D006801:Humans; D010787:Photosensitivity Disorders / Q000139:chemically induced / Q000175:diagnosis / Q000628:therapy; D012307:Risk Factors; D012713:Serum Sickness / Q000139:chemically induced / Q000175:diagnosis / Q000628:therapy; D014581:Urticaria / Q000139:chemically induced / Q000175:diagnosis / Q000628:therapy
D000305:Adrenal Cortex Hormones; D004643:Emollients; D006634:Histamine H1 Antagonists