title: XtalPred: a web server for prediction of protein crystallizability.
abstract: XtalPred is a web server for prediction of protein crystallizability. The prediction is made by comparing several features of the protein with distributions of these features in TargetDB and combining the results into an overall probability of crystallization. XtalPred provides: (1) a detailed comparison of the protein's features to the corresponding distribution from TargetDB; (2) a summary of protein features and predictions that indicate problems that are likely to be encountered during protein crystallization; (3) prediction of ligands; and (4) (optional) lists of close homologs from complete microbial genomes that are more likely to crystallize.
  
  
  BACKGROUND
  The XtalPred web server is freely available for academic users on http://ffas.burnham.org/XtalPred
authors.affiliation: Joint Center for Structural Genomics, La Jolla, CA 92037, USA.
authors.forename: Lukasz
authors.initials: L
authors.lastname: Slabinski
authors.forename: Lukasz
authors.initials: L
authors.lastname: Jaroszewski
authors.forename: Leszek
authors.initials: L
authors.lastname: Rychlewski
authors.forename: Ian A
authors.initials: IA
authors.lastname: Wilson
authors.forename: Scott A
authors.initials: SA
authors.lastname: Lesley
authors.forename: Adam
authors.initials: A
authors.lastname: Godzik
mesh_terms: D003198:Computer Simulation; D003460:Crystallization / Q000379:methods*; D003461:Crystallography / Q000379:methods; D020407:Internet; D008956:Models, Chemical; D008958:Models, Molecular; D011487:Protein Conformation; D011506:Proteins / Q000737:chemistry* / Q000648:ultrastructure*; D020539:Sequence Analysis, Protein / Q000379:methods*; D012984:Software
chemical_list: D011506:Proteins