From nutraceuticals to pharmaceuticals to nanopharmaceuticals: a case study in angiogenesis modulation during oxidative stress.
This report reviews the potential applications of nanotechnology in various therapeutics and diagnostics areas with special emphasis on key frontiers in angiogenesis modulation using naturally driven drug targets including compounds that modulate oxidative stress and inflammatory pathways for the potential treatment of vascular, cancer, inflammatory, and ocular disorders. Recent advances of the nanotechnology mediated gene delivery are also described in this paper.
Mousa
Shaker A
SA
Pharmaceutical Research Institute, Albany College of Pharmacy, Albany, NY, USA. mousas@acp.edu
Bharali
Dhruba J
DJ
Armstrong
Donald
D
D000818:Animals; D016503:Drug Delivery Systems; D018014:Gene Transfer Techniques; D006801:Humans; D053758:Nanoparticles / Q000627:therapeutic use*; D036103:Nanotechnology / Q000379:methods*; D009389:Neovascularization, Pathologic / Q000188:drug therapy*; D018384:Oxidative Stress