Development of in situ melanoma after allogeneic bone marrow transplantation in Griscelli syndrome type II.
GS is an uncommon autosomal recessive disorder characterized by pigmentary dilution of the skin and hair and in most patients by abnormal regulation of the immune system. Childhood melanoma is rare in the pediatric population. The best prognosis is achieved with early diagnosis and definitive surgical excision of melanoma. We report a case of a patient with GS type II and melanoma who was successfully treated by allogeneic bone marrow transplantation and surgical excision of the melanoma.
Köse
Osman
O
Department of Dermatology, Gülhane School of Medicine, Ankara, Turkey. okose@gata.edu.tr
Kürekçi
Ahmet Emin
AE
Safali
Mükerrem
M
Akin
Ridvan
R
Köseoğlu
Vedat
V
Tezcan
Ilhan
I
D000293:Adolescent; D016026:Bone Marrow Transplantation / Q000009:adverse effects*; D005260:Female; D006801:Humans; D007153:Immunologic Deficiency Syndromes / Q000601:surgery*; D008545:Melanoma / Q000473:pathology* / Q000601:surgery; D010859:Pigmentation Disorders / Q000601:surgery; D012878:Skin Neoplasms / Q000473:pathology* / Q000601:surgery; D014184:Transplantation, Homologous; D016896:Treatment Outcome