title: Influence of evoked compound action potential on speech perception in cochlear implant users.
abstract: Electrically Evoked Compound Action Potential is a measure of synchronous cochlear nerve fibers activity elicited by electrical stimulation of the cochlear implant. The electrophysiological nerve responses may contribute to explain the variability in individual performance of cochlear implant recipients.
  
  
  OBJECTIVE
  To compare speech perception tests performances of cochlear implant users according to the presence or absence of intraoperative neural telemetry responses.
  
  
  METHODS
  Prospective study design with 100 "Nucleus 24" cochlear implant users divided in two groups according to the presence or absence of intraoperative neural telemetry responses. Speech perception tests were performed after 6 months of continuous use of the device and compared among groups.
  
  
  RESULTS
  Intraoperative action potentials were observed in 72 % of individuals. Open-set sentence test results were better in implant users who had neural telemetry responses when compared to implant users in whom this potential was absent (averages 82.8 % versus 41 %, p = 0.005). There was a strong association between post meningitis-related deafness and absence of intraoperative potentials.
  
  
  CONCLUSIONS
  The absence of intraoperative neural telemetry responses was associated with worse performances in speech perception tests and meningitis as etiology of deafness. On the other hand, the presence of these potentials suggests excellent prognosis.
authors.affiliation: Otorhinolaryngology, University of São Paulo Medical School, São Paulo, Brazil. mariana.guedes@politec.net
authors.forename: Mariana Cardoso
authors.initials: MC
authors.lastname: Guedes
authors.forename: Raimar
authors.initials: R
authors.lastname: Weber
authors.forename: Maria Valéria S Goffi
authors.initials: MV
authors.lastname: Gomez
authors.forename: Rubens Vuono de Brito
authors.initials: RV
authors.lastname: Neto
authors.forename: Cristina Gomes O
authors.initials: CG
authors.lastname: Peralta
authors.forename: Ricardo Ferreira
authors.initials: RF
authors.lastname: Bento
mesh_terms: D000293:Adolescent; D000328:Adult; D001309:Auditory Threshold / Q000502:physiology; D002648:Child; D002675:Child, Preschool; D019929:Cochlear Implantation; D003638:Deafness / Q000601:surgery*; D004558:Electric Stimulation; D005072:Evoked Potentials, Auditory / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D011446:Prospective Studies; D013067:Speech Perception / Q000502:physiology*