Signposts of docking and scoring in drug design.
Docking and scoring tools are often used in the early stages of drug discovery projects today. Because the language of this field of drug design often includes intermingled terms of physics, chemistry, biology, and medicine, the significant developments of docking and scoring are challenging to follow for non-experts. In this Science Philosophy article, I attempt to clarify the concepts used in docking and scoring to help articulate the successes and limitations of this multidisciplinary field in more comprehensible manner.
Gani
Osman A B S M
OA
Department of Pharmacology, Institute of Medical Biology, Faculty of Medicine, University of Tromsø, 9037 Tromsø, Norway. osman.gani@fagmed.uit.no
D000465:Algorithms; D015195:Drug Design; D008958:Models, Molecular; D011487:Protein Conformation; D012984:Software