title: Expression of the sigmaF-directed csfB locus prevents premature appearance of sigmaG activity during sporulation of Bacillus subtilis.
abstract: During sporulation, sigma(G) becomes active in the prespore upon the completion of engulfment. We show that the inactivation of the sigma(F)-directed csfB locus resulted in premature activation of sigma(G). CsfB exerted control distinct from but overlapping with that exerted by LonA to prevent inappropriate sigma(G) activation. The artificial induction of csfB severely compromised spore formation.
authors.affiliation: Department of Microbiology and Immunology, Temple University School of Medicine, 3400 North Broad St., Philadelphia, PA 19140, USA.
authors.forename: Vasant K
authors.initials: VK
authors.lastname: Chary
authors.forename: Panagiotis
authors.initials: P
authors.lastname: Xenopoulos
authors.forename: Patrick J
authors.initials: PJ
authors.lastname: Piggot
mesh_terms: D001412:Bacillus subtilis / Q000235:genetics* / Q000254:growth & development / Q000378:metabolism*; D001426:Bacterial Proteins / Q000378:metabolism*; D015964:Gene Expression Regulation, Bacterial; D012808:Sigma Factor / Q000378:metabolism*; D013171:Spores, Bacterial / Q000235:genetics* / Q000378:metabolism*; D013997:Time Factors
chemical_list: D001426:Bacterial Proteins; C064971:FliA protein, Bacteria; D012808:Sigma Factor