Clinical efficiency and safety analysis of transcatheter interventional therapy for compound congenital cardiovascular abnormalities.
OBJECTIVE
To investigate the efficiency and safety of transcatheter interventional therapy for compound congenital cardiovascular abnormalities.


METHODS
From Nov 2001 to Jun 2006, a total of 36 patients (17 male, 19 female), aged 17.20 +/- 10.52, with compound congenital cardiovascular abnormalities underwent transcatheter interventional procedure. These patients included 11 with perimembranous ventricular septal defect (PVSD) and patent ductus arteriosus (PDA), 8 patients with PVSD and atrial septal defect (ASD), 8 patients with ASD and PDA, 7 patients with ASD and pulmonary stenosis (PS), 1 patient with ASD and mitral stenosis(MS), 1 patient with coarctation of aorta (COA) and PDA. According to the principle of "easy first, hard second," balloon valvuloplasties of PS or MS were performed before the closure of PVSD, and of PDA and ASD. Electrocardiogram and transthoracic echocardiogram were examined at 4 days, 1, 2, 6 and 12 months, respectively, after each procedure.


RESULTS
Transcatheter interventional therapy for compound congenital cardiovascular abnormalities was successful in all patients. Among these, 2 occluders were planted in each of 27 patients, 7 patients with ASD combined with PS and 1 patient with ASD combined with MS underwent successfully performed balloon valvuloplasty and ASD closure, 1 patient with COA combined with PDA underwent successfully performed balloon valvuloplasty and subsequent covered stent implantation. No patient encountered serious adverse events during the (30.5 +/- 14.6) months of follow-up.


CONCLUSIONS
Transcatheter interventional therapy for compound congenital cardiovascular abnormalities could obtain satisfactory results with technical feasibility.
Song
Zhi-Yuan
ZY
Department of Cardiology, Southwest Hospital, The Third Military Medical University, Chongqing, China. zysong@public.cta.cq.cn
Shu
Mao-Qin
MQ
Hu
Hou-Yuan
HY
Tong
Shi-Fei
SF
Ran
Bo-Li
BL
Liu
Jian-Pin
JP
Li
Yong-Hua
YH
He
Guo-Xiang
GX
D000293:Adolescent; D001017:Aortic Coarctation; D006328:Cardiac Catheterization / Q000009:adverse effects / Q000379:methods*; D005240:Feasibility Studies; D005260:Female; D006330:Heart Defects, Congenital / Q000628:therapy*; D006345:Heart Septal Defects, Ventricular; D006801:Humans; D008185:Lutembacher Syndrome; D008297:Male; D011446:Prospective Studies; D011666:Pulmonary Valve Stenosis