The curability of follicular lymphoma.
Follicular lymphoma has been widely thought to be an incurable disease. However, if cure is defined as a remission that continues indefinitely and the patient eventually dies of another disease, some patients with follicular lymphoma are cured. Follicular lymphoma grade 3 acts much like diffuse large B-cell lymphoma, and cure is frequent. Even in follicular lymphoma grade 1 and 2, some patients have durable responses to initial therapy, and a significant proportion of patients can have durable responses after hematopoietic stem cell transplantation.
Lunning
Matthew
M
University of Nebraska Medical Center, Omaha, NE 68583, USA. mlunning@unmc.edu
Armitage
James O
JO
D000818:Animals; D018380:Hematopoietic Stem Cell Transplantation; D006801:Humans; D008224:Lymphoma, Follicular / Q000401:mortality / Q000628:therapy*; D016403:Lymphoma, Large B-Cell, Diffuse / Q000401:mortality / Q000628:therapy*; D009367:Neoplasm Staging; D014184:Transplantation, Homologous