Rabies encephalitis.
A 12-year-old boy presented with fever and sore throat of 6 days duration followed by vomiting and altered sensorium. He had received 4 doses of antirabies vaccine following a dog bite 4 weeks back. Rabies immunoglobulin was not given. History of hydrophobia and aerophobia were strikingly absent. The possibilities of rabies encephalitis and vaccine induced acute disseminated encephalomyelitis (ADEM) were considered. MRI brain showed exclusive grey matter changes characteristic of rabies. The diagnosis was further confirmed by serological tests.
Mohite
Ambeshprasad
A
Department of Pediatrics, Amrita Institute of Medical Sciences and Research Center, Kochi, Kerala, India.
Prasad
Vinitha
V
Rajam
L
L
Madhusudana
S N
SN
D000818:Animals; D001733:Bites and Stings / Q000150:complications; D002648:Child; D018450:Disease Progression; D004285:Dogs; D018792:Encephalitis, Viral / Q000175:diagnosis* / Q000209:etiology; D017809:Fatal Outcome; D006801:Humans; D008297:Male; D011818:Rabies / Q000175:diagnosis* / Q000209:etiology; D011820:Rabies virus / Q000302:isolation & purification*; D012720:Severity of Illness Index