Engineered muscle: a tool for studying muscle physiology and function.
Recent advances in skeletal muscle tissue engineering have resulted in an in vitro tissue model that can be used for studying the effects of genetic alterations, pharmacological interventions, and exercise on muscle physiology and function. Here, we present applications for this technology to further our understanding of the molecular mechanisms underlying skeletal muscle adaptation in response to exercise.
Khodabukus
Alastair
A
Division of Molecular Physiology, University of Dundee, Dundee, United Kingdom.
Paxton
Jennifer Z
JZ
Donnelly
Kenneth
K
Baar
Keith
K
D015444:Exercise / Q000502:physiology; D006801:Humans; D008954:Models, Biological; D018485:Muscle Fibers, Skeletal; D018482:Muscle, Skeletal / Q000502:physiology*; D023822:Tissue Engineering; D006113:United Kingdom