title: Contact lens strategies for the patient with dry eye.
abstract: Dry eye is the most common reason for contact lens (CL) discontinuation, and the patient with pre-existing dry eye presents particular challenges to the CL fitter. Poor tear film quality/stability, oxygen deprivation, lens deposits, and adverse reactions to CL solutions all contribute to dry eye, and lid disease, allergies, environmental factors, and medications can further hamper successful CL wear by the patient with dry eye. Health and comfort of the ocular surface is affected by the water content, ionicity, oxygen permeability, and modulus of elasticity of the lens, as well as by surface characteristics, such as protein, lipid, and mucin deposition; protein adsorption; and wettability. The choice of CL cleaning solutions with regard to action, cytotoxicity, and biocompatibility are as important as the choice of the CL itself. With appropriate management of the lid, meibomian gland, and ocular surface conditions that produce dry eye, careful selection of lenses and solutions, and vigilant follow-up, successful CL wear should be achievable for the dry eye patient.
authors.affiliation: University of Iowa, Department of Ophthalmology and Visual Sciences, Iowa City, Iowa 52242, USA. Christine-sindt@uiowa.edu
authors.forename: Christine W
authors.initials: CW
authors.lastname: Sindt
authors.forename: Reid A
authors.initials: RA
authors.lastname: Longmuir
mesh_terms: D018639:Contact Lens Solutions; D003263:Contact Lenses, Hydrophilic; D015352:Dry Eye Syndromes / Q000150:complications* / Q000209:etiology; D006801:Humans; D009883:Ophthalmic Solutions; D010100:Oxygen / Q000378:metabolism; D017755:Prosthesis Fitting; D012030:Refractive Errors / Q000628:therapy*; D013501:Surface-Active Agents; D013666:Tears / Q000378:metabolism; D017155:Wettability
chemical_list: D018639:Contact Lens Solutions; D009883:Ophthalmic Solutions; D013501:Surface-Active Agents; D010100:Oxygen