Enhancement of magnetization transfer effects by inter-molecular multiple quantum filtered NMR.
There are a number of methods that give MRI contrasts based on changes of the water M(z) magnetization as a result of magnetization transfer to macromolecules. In the present work we report that a combination of these methods with inter-molecular multiple quantum coherences (iMQC) gives enhanced effects. For the magnetization transfer contrast (MTC) method an effect of (M(z)/M(0)) becomes (M(z)/M(0))(l) where l is the rank of the tensors constituting the iMQC. A similar trend was found upon combining iMQC with the Goldman-Shen experiment. It is pointed out that the method is general for all magnetization transfer methods, including the nuclear Overhauser effect.
Eliav
Uzi
U
School of Chemistry, Tel Aviv University, Ramat Aviv, Tel Aviv 69978, Israel.
Navon
Gil
G
D000818:Animals; D002417:Cattle; D005976:Glutaral / Q000737:chemistry; D007089:Image Enhancement / Q000379:methods; D008279:Magnetic Resonance Imaging / Q000379:methods*; D009900:Optic Nerve / Q000033:anatomy & histology*; D019047:Phantoms, Imaging; D012710:Serum Albumin, Bovine / Q000737:chemistry; D012815:Signal Processing, Computer-Assisted
D012710:Serum Albumin, Bovine; D005976:Glutaral