title: Hypertrophic spinal pachymeningitis associated with heavy-chain disease. Case report.
abstract: The authors present a case of concurrent hypertrophic spinal pachymeningitis (HSP) and heavy-chain disease (HCD). The patient was a 71-year-old woman presenting with leg paralysis and fever. Laminectomy was performed for thoracic HSP, and chemotherapy was administered for HCD. Because the dura mater was not surgically opened, marked hypertrophy remained postoperatively. Once the HCD was controlled by chemotherapy, the fever subsided and the hypertrophy was resolved. No previous reports have supported a link between the two diseases. Idiopathic HSP may be secondary to rare conditions such as HCD, and systemic examinations should be performed to the fullest extent possible to investigate the possibility of some underlying disease.
authors.affiliation: Department of Orthopedic Surgery, Matsuyama City Hospital, Matsuyama City, Japan. yunoka@xk9.so-net.ne.jp
authors.forename: Kazuki
authors.initials: K
authors.lastname: Yunokawa
authors.forename: Yoshitaka
authors.initials: Y
authors.lastname: Hagiyama
authors.forename: Yu
authors.initials: Y
authors.lastname: Mochizuki
authors.forename: Nobuhiro
authors.initials: N
authors.lastname: Tanaka
authors.forename: Mitsuo
authors.initials: M
authors.lastname: Ochi
mesh_terms: D000368:Aged; D004388:Dura Mater / Q000473:pathology*; D005260:Female; D006362:Heavy Chain Disease / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D006801:Humans; D006984:Hypertrophy / Q000175:diagnosis / Q000209:etiology / Q000628:therapy; D008581:Meningitis / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy