Amphidinolides B6 and B7, cytotoxic macrolides from a symbiotic dinoflagellate Amphidinium species.
Two 26-membered macrolides, amphidinolides B6 ( 2) and B7 ( 1), have been isolated from a marine symbiotic dinoflagellate Amphidinium sp., and the structures were elucidated on the basis of detailed analyses of 2D NMR data. The relative and absolute configurations for 1 and 2 were assigned by comparison of NMR data and CD data with those of known amphidinolides.
Oguchi
Keiko
K
Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo 060-0812, Japan.
Tsuda
Masashi
M
Iwamoto
Rie
R
Okamoto
Yumiko
Y
Endo
Taeko
T
Kobayashi
Jun'ichi
J
Ozawa
Tomoko
T
Masuda
Atsunori
A
D000818:Animals; D002942:Circular Dichroism; D004141:Dinoflagellida / Q000737:chemistry*; D018942:Macrolides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D000097442:Amphidinolides
D018942:Macrolides; C524980:amphidinolide B6; D000097442:Amphidinolides; C524981:amphidinolide B7