[Endometrial ablation versus hysterectomy in women treated with tamoxifen].
OBJECTIVE
The aim of our study is the assessment of the importance of the endometrial ablation versus hysterectomy in patients treated with tamoxifen for previous breast cancer.


METHODS
Fifty-eight outpatients in therapy with tamoxifen for 1 year were controlled in the Department of Gynaecology of the University of Naples. We have selected these patients in two groups: group A, with 28 women with abnormal uterine bleeding and endometrial thickness >8 mm and group B, with 30 normal endometrium asymptomatic women. All patient of group A and 18 of group B were treated with endometrial ablation.


RESULTS
Next follow-up showed normal hysteroscopy figures in 89% of cases and 5% of cases needed a hysterectomy for new abnormal uterine bleeding and cytology.


CONCLUSIONS
Our results show the utility of endometrial ablation especially in selected cases in therapy with tamoxifen for previous breast cancer.
Capuano
I
I
Dipartimento di Scienze Ginecologiche Ostetriche e della Riproduzione, Seconda Università degli Studi di Napoli, Napoli, Italy.
Caporale
A
A
Vagnetti
P
P
Di Domenico
A
A
Felicetti
M
M
Torella
M
M
Borrelli
A L
AL
D018931:Antineoplastic Agents, Hormonal / Q000008:administration & dosage / Q000009:adverse effects*; D001943:Breast Neoplasms / Q000188:drug therapy; D017115:Catheter Ablation / Q000379:methods; D004717:Endometrium / Q000187:drug effects* / Q000601:surgery*; D005260:Female; D006801:Humans; D007044:Hysterectomy / Q000379:methods; D015907:Hysteroscopy / Q000379:methods; D012189:Retrospective Studies; D013629:Tamoxifen / Q000008:administration & dosage / Q000009:adverse effects*; D016896:Treatment Outcome; D014592:Uterine Hemorrhage / Q000139:chemically induced / Q000601:surgery*
D018931:Antineoplastic Agents, Hormonal; D013629:Tamoxifen