title: Combined voriconazole plus caspofungin therapy for the treatment of probable Geotrichum pneumonia in a leukemia patient.
abstract: Infections by Geotrichum capitatum, occurring in leukemia patients, are rarely reported and generally are characterized by a poor prognosis. Here we reported a case of G. capitatum pneumonia in a patient with plasma cell leukemia, successfully treated with antifungal combination with voriconazole and caspofungin and supportive therapy.
authors.affiliation: Istituto di Ematologia, Università Cattolica del Sacro Cuore, Largo A. Gemelli 8, 00168, Rome, Italy. luanafianchi@libero.it
authors.forename: L
authors.initials: L
authors.lastname: Fianchi
authors.forename: L
authors.initials: L
authors.lastname: Montini
authors.forename: M
authors.initials: M
authors.lastname: Caira
authors.forename: M T
authors.initials: MT
authors.lastname: Voso
authors.forename: R
authors.initials: R
authors.lastname: Maviglia
authors.forename: B
authors.initials: B
authors.lastname: Posteraro
authors.forename: L
authors.initials: L
authors.lastname: Pagano
mesh_terms: D000368:Aged; D000935:Antifungal Agents / Q000008:administration & dosage* / Q000494:pharmacology / Q000627:therapeutic use; D000077336:Caspofungin; D004359:Drug Therapy, Combination; D054714:Echinocandins / Q000008:administration & dosage* / Q000494:pharmacology / Q000627:therapeutic use; D005260:Female; D005847:Geotrichosis / Q000188:drug therapy* / Q000382:microbiology; D005848:Geotrichum; D006801:Humans; D016867:Immunocompromised Host; D007952:Leukemia, Plasma Cell / Q000150:complications / Q000188:drug therapy; D055666:Lipopeptides; D008172:Lung Diseases, Fungal / Q000150:complications / Q000188:drug therapy* / Q000382:microbiology; D011743:Pyrimidines / Q000008:administration & dosage* / Q000494:pharmacology / Q000627:therapeutic use; D014230:Triazoles / Q000008:administration & dosage* / Q000494:pharmacology / Q000627:therapeutic use; D065819:Voriconazole
chemical_list: D000935:Antifungal Agents; D054714:Echinocandins; D055666:Lipopeptides; D011743:Pyrimidines; D014230:Triazoles; D000077336:Caspofungin; D065819:Voriconazole