Enantioselective Tsuji allylations.
The family of allylation reactions developed by Tsuji in the 1980s are capable of generating tertiary and quaternary carbon stereocenters from several synthetic precursors. Despite the utility of these transformations, they have seen little use in the synthesis of natural products. Recently, the power of these reactions was significantly enhanced by the development of enantioselective versions of these transformations. Applications of these methods to the enantioselective syntheses of natural products and pharmaceutical compounds highlight the importance of these developments.
Mohr
Justin T
JT
The Arnold and Mabel Beckman Laboratories of Chemical Synthesis, Division of Chemistry and Chemical Engineering, California Institute of Technology, 1200 East California Boulevard, MC 164-30, Pasadena, CA 91125, USA.
Stoltz
Brian M
BM
D002254:Carbonates / Q000737:chemistry; D003516:Cycloparaffins / Q000737:chemistry; D004952:Esters / Q000737:chemistry; D004987:Ethers / Q000737:chemistry; D008956:Models, Chemical; D013237:Stereoisomerism
D002254:Carbonates; D003516:Cycloparaffins; D004952:Esters; D004987:Ethers