Source localization of auditory evoked potentials after cochlear implantation.
Little is known about how the auditory cortex adapts to artificial input as provided by a cochlear implant (CI). We report the case of a 71-year-old profoundly deaf man, who has successfully used a unilateral CI for 4 years. Independent component analysis (ICA) of 61-channel EEG recordings could separate CI-related artifacts from auditory-evoked potentials (AEPs), even though it was the perfectly time-locked CI stimulation that caused the AEPs. AEP dipole source localization revealed contralaterally larger amplitudes in the P1-N1 range, similar to normal hearing individuals. In contrast to normal hearing individuals, the man with the CI showed a 20-ms shorter N1 latency ipsilaterally. We conclude that ICA allows the detailed study of AEPs in CI users.
Debener
Stefan
S
MRC Institute of Hearing Research Southampton, Southampton, UK. sdebener@soton.ac.uk
Hine
Jemma
J
Bleeck
Stefan
S
Eyles
Julie
J
D000161:Acoustic Stimulation; D000368:Aged; D016477:Artifacts; D019929:Cochlear Implantation / Q000523:psychology*; D003627:Data Interpretation, Statistical; D003638:Deafness / Q000503:physiopathology / Q000523:psychology; D004569:Electroencephalography; D005072:Evoked Potentials, Auditory / Q000502:physiology*; D006801:Humans; D008297:Male; D008959:Models, Neurological; D013017:Sound Localization / Q000502:physiology*