title: Differential activities of newer antifungal agents against Candida albicans and Candida parapsilosis biofilms.
abstract: The activities of voriconazole, posaconazole, caspofungin, and anidulafungin against Candida albicans and Candida parapsilosis biofilms were evaluated. In contrast to planktonic cells, the MICs for voriconazole and posaconazole for the biofilms of the two species were high (>or=256 and >64 mg/liter, respectively) but relatively low for the echinocandins caspofungin and anidulafungin (<or=1 and <or=2 mg/liter, respectively).
authors.affiliation: Laboratory of Infectious Diseases, Third Department of Pediatrics, Aristotle University, Hippokration Hospital, 54642 Thessaloniki, Greece.
authors.forename: Aspasia
authors.initials: A
authors.lastname: Katragkou
authors.forename: Athanasios
authors.initials: A
authors.lastname: Chatzimoschou
authors.forename: Maria
authors.initials: M
authors.lastname: Simitsopoulou
authors.forename: Maria
authors.initials: M
authors.lastname: Dalakiouridou
authors.forename: Eudoxia
authors.initials: E
authors.lastname: Diza-Mataftsi
authors.forename: Chaido
authors.initials: C
authors.lastname: Tsantali
authors.forename: Emmanuel
authors.initials: E
authors.lastname: Roilides
mesh_terms: D000935:Antifungal Agents / Q000494:pharmacology*; D001393:Azoles / Q000494:pharmacology; D018441:Biofilms / Q000187:drug effects*; D002175:Candida / Q000145:classification / Q000187:drug effects*; D002176:Candida albicans / Q000187:drug effects*; D054714:Echinocandins / Q000494:pharmacology; D006801:Humans; D008826:Microbial Sensitivity Tests
chemical_list: D000935:Antifungal Agents; D001393:Azoles; D054714:Echinocandins