Product deuterium isotope effect for orotidine 5'-monophosphate decarboxylase: evidence for the existence of a short-lived carbanion intermediate.
Toth
Krisztina
K
Department of Chemistry, University at Buffalo, Buffalo, New York 14260, USA.
Amyes
Tina L
TL
Wood
Bryant M
BM
Chan
Kui
K
Gerlt
John A
JA
Richard
John P
JP
D002244:Carbon / Q000737:chemistry*; D003903:Deuterium; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D009964:Orotidine-5'-Phosphate Decarboxylase / Q000737:chemistry* / Q000378:metabolism*; D014542:Uridine Monophosphate / Q000031:analogs & derivatives / Q000737:chemistry / Q000378:metabolism
C005417:orotidylic acid; D002244:Carbon; D003903:Deuterium; D014542:Uridine Monophosphate; D009964:Orotidine-5'-Phosphate Decarboxylase