Secondary sternal Aspergillus osteomyelitis in a diabetic hemodialysis patient with previous allograft rejection.
A 29-year-old diabetic woman who had a previously failed renal allograft on maintenance hemodialysis developed sternal aspergillosis with Aspergillus terreus following a pericardiectomy. She was successfully treated with surgical debridement and a combination of antifungal agents including amphotericin B, caspofungin, and voriconizole. The diagnostic difficulties and management are discussed.
Natesan
Sinthumathi
S
Sri Ramachandra Medical College and Research Institute, Chennai, India.
Abraham
Georgi
G
Mathew
Milly
M
Lalitha
M K
MK
Srinivasan
C N
CN
D000328:Adult; D000935:Antifungal Agents / Q000627:therapeutic use; D001228:Aspergillosis / Q000175:diagnosis / Q000382:microbiology / Q000628:therapy*; D001230:Aspergillus / Q000302:isolation & purification; D003922:Diabetes Mellitus, Type 1 / Q000150:complications / Q000175:diagnosis / Q000628:therapy; D003928:Diabetic Nephropathies / Q000150:complications / Q000175:diagnosis / Q000628:therapy*; D005260:Female; D006084:Graft Rejection / Q000150:complications* / Q000628:therapy; D006801:Humans; D016030:Kidney Transplantation / Q000009:adverse effects*; D010019:Osteomyelitis / Q000175:diagnosis / Q000382:microbiology / Q000628:therapy*; D010490:Pericardial Effusion / Q000209:etiology / Q000601:surgery; D006435:Renal Dialysis / Q000009:adverse effects*; D014184:Transplantation, Homologous; D016896:Treatment Outcome
D000935:Antifungal Agents