Fine needle aspiration cytology of basal cell adenoma of the salivary gland.
OBJECTIVE
To formulate cytologic features for differential diagnosis of basal cell adenoma (BCA).


METHODS
The usefulness of 5 items for a cytologically definitive diagnosis of BCA was examined. The 5 items in 8 BCA and 22 non-BCA cases (adenoid cystic carcinoma [ADCC], basal cell adenocarcinoma, myoepithelioma, pleomorphic adenoma and polymorphous low-grade adenocarcinoma) that displayed mimicking cytology were examined cytologically.


RESULTS
The useful items were < 5.1 microm in mean of epithelial nuclear short diameter; mild atypia on definitive diagnosis; stromal cell cluster combining smooth margin surrounding the epithelial cell cluster or containing the epithelial cell cluster; epithelial clusters surrounded by or adhered to a thick, hyalinized smooth margin without stromal cluster; and closely fastened, tight clusters with denser cytoplasm than ADCC, but an indistinct border, with oval nuclei and no hyaline cells.


CONCLUSIONS
Five items are useful criteria for BCA.
Hara
Hitoshi
H
Pathology Division, Yamanashi Prefectural Central Hospital, Yamanashi, Kofu City, Japan. hara2@bird.ocn.ne.jp
Oyama
Toshio
T
Saku
Takashi
T
D000230:Adenocarcinoma / Q000473:pathology; D000236:Adenoma / Q000175:diagnosis / Q000473:pathology* / Q000648:ultrastructure; D044963:Biopsy, Fine-Needle; D003528:Carcinoma, Adenoid Cystic / Q000473:pathology; D002467:Cell Nucleus / Q000473:pathology; D003937:Diagnosis, Differential; D004848:Epithelium / Q000473:pathology / Q000648:ultrastructure; D006801:Humans; D007150:Immunohistochemistry; D009208:Myoepithelioma / Q000473:pathology; D053141:Organelle Size; D012468:Salivary Gland Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000648:ultrastructure; D012469:Salivary Glands / Q000473:pathology*; D017154:Stromal Cells / Q000473:pathology