title: Renewed hope for a vaccine against the intestinal adult Taenia solium.
abstract: Review of experimental and observational evidence about various cestode infections of mammalian hosts revives hope for the development of an effective vaccine against adult intestinal tapeworms, the central protagonists in their transmission dynamics. As for Taenia solium, there are abundant immunological data regarding cysticercosis in humans and pigs, but information about human taeniasis is scarce. A single publication reporting protection against T. solium taeniasis by experimental primo infection and by vaccination of an experimental foster host, the immunocompetent female hamster, kindles the hope of a vaccine against the tapeworm to be used in humans, its only natural definitive host.
authors.affiliation: Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, A.P. 70228, DF México. edda@servidor.unam.mx
authors.forename: Edda
authors.initials: E
authors.lastname: Sciutto
authors.forename: Gabriela
authors.initials: G
authors.lastname: Rosas
authors.forename: Carmen
authors.initials: C
authors.lastname: Cruz-Revilla
authors.forename: Andrea
authors.initials: A
authors.lastname: Toledo
authors.forename: Jacquelynne
authors.initials: J
authors.lastname: Cervantes
authors.forename: Marisela
authors.initials: M
authors.lastname: Hernández
authors.forename: Beatríz
authors.initials: B
authors.lastname: Hernándezt
authors.forename: Fernando A
authors.initials: FA
authors.lastname: Goldbaum
authors.forename: Aline S
authors.initials: AS
authors.lastname: de Aluja
authors.forename: Gladis
authors.initials: G
authors.lastname: Fragoso
authors.forename: Carlos
authors.initials: C
authors.lastname: Larralde
mesh_terms: D000818:Animals; D000871:Anthelmintics / Q000627:therapeutic use; D002353:Carrier State / Q000188:drug therapy / Q000517:prevention & control*; D006801:Humans; D007411:Intestinal Diseases, Parasitic / Q000517:prevention & control*; D041201:Taenia solium / Q000276:immunology*; D013622:Taeniasis / Q000188:drug therapy / Q000517:prevention & control*; D014612:Vaccines
chemical_list: D000871:Anthelmintics; D014612:Vaccines