[Study on extraction and purification of active parts from Da Chuan Xiong Fang for treatment of migraine].
OBJECTIVE
To study on the process of extraction and purification of active parts from Da Chuan Xiong Fang for treatment of migraine.


METHODS
the process of extraction and purification of active parts with ferulic acid and gastrodin were optimized respectively by direct comparison and orthogonal design.


RESULTS
Paste rate of active parts with ferulic acid was. 1.67% and the content of ferulic acid was 5.82%. Paste rate of active parts with gastrodin was 5.38% and the content of gastrodin was 8.45%.


CONCLUSIONS
Active parts from Da Chuan Xiong Fang for treatment of migraine are extracted and purified effectively.
Hong
Yan-Long
YL
School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203.
Feng
Yi
Y
Xu
De-Sheng
DS
Liu
Hong-Jie
HJ
D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000737:chemistry / Q000302:isolation & purification / Q000627:therapeutic use; D019661:Apiaceae / Q000737:chemistry; D002851:Chromatography, High Pressure Liquid / Q000295:instrumentation / Q000379:methods; D003373:Coumaric Acids / Q000032:analysis / Q000302:isolation & purification* / Q000627:therapeutic use; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification* / Q000627:therapeutic use; D000431:Ethanol / Q000737:chemistry; D031668:Gastrodia / Q000737:chemistry; D005960:Glucosides / Q000032:analysis / Q000302:isolation & purification* / Q000627:therapeutic use; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008881:Migraine Disorders / Q000188:drug therapy*; D035281:Plant Tubers / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D027343:Rhizome / Q000737:chemistry; D012997:Solvents / Q000737:chemistry; D013678:Technology, Pharmaceutical / Q000379:methods
D000894:Anti-Inflammatory Agents, Non-Steroidal; D003373:Coumaric Acids; D004365:Drugs, Chinese Herbal; D005960:Glucosides; D012997:Solvents; C530158:chuan xiong fang; D000431:Ethanol; C004999:ferulic acid