title: Vaccine immunopotentiators of the future.
abstract: Vaccine adjuvants or immunopotentiators comprise a diverse group of molecules or formulations. Despite a wealth of different candidates, there is a need for better vaccine adjuvants in both veterinary and human medicine. For human vaccines, the immunopotentiator choice has been limited to aluminum salts, until recently. By contrast, a whole range of adjuvants is employed for inactivated veterinary vaccines, due to less stringent safety and regulatory requirements and proven superior vaccine performance. This review highlights recent developments and future trends in immunopotentiators.
authors.affiliation: Department of Vaccine Technology and Immunology R&D, Intervet International BV, Boxmeer, The Netherlands. virgil.schijns@intervet.com
authors.forename: V E J C
authors.initials: VE
authors.lastname: Schijns
authors.forename: W G J
authors.initials: WG
authors.lastname: Degen
mesh_terms: D000276:Adjuvants, Immunologic / Q000008:administration & dosage / Q000494:pharmacology*; D017607:Aluminum Compounds; D000818:Animals; D015195:Drug Design; D004357:Drug Synergism; D004655:Emulsions; D005544:Forecasting; D006801:Humans; D053758:Nanoparticles; D014612:Vaccines / Q000494:pharmacology
chemical_list: D000276:Adjuvants, Immunologic; D017607:Aluminum Compounds; D004655:Emulsions; D014612:Vaccines