title: [Surgical correction of male external genitalia giant condyloma acuminata].
abstract: OBJECTIVE
  To observe the clinical efficiency of curettage combining circumcision on giant condyloma acuminata(CA) in male external genitalia, the relationship between recurrence and curettage depth, the possibility of HPV infection in PBMC after operation.
  
  
  METHODS
  Curettage combining circumcision was carried out on 50 cases with CA. The removed wart and wound surface tissues were examined under light microcope and for HPV-DNA detection by PCR. HPV-DNA was detected in PBMC during < or =1 and > or =2 weeks after operation.
  
  
  RESULTS
  (1) 46 cases were cured completely after one treating (once the cure rate is 92%), 4 cases twice(twice the cure rate is 8%); (2) The tissues were proved to be HPV-DNA positive by PCR amplification and CA relapse occurred; (3) HPV-DNA was detected in PBMC only within the week after curettage in the 19 cases.
  
  
  CONCLUSIONS
  (1) The clinical efficiency of curettage combining circumcision on giant condyloma acuminata in male external genitalia is sure; (2) Cure rate and relapse rate are related with curettage depth; (3) Transient positive HPV-DNA in PBMC may be detected.
authors.affiliation: Dongguan Medical Cosmetologe Centre, Dongguan 523008, China. yun63@21cn.com
authors.forename: Xiao-yun
authors.initials: XY
authors.lastname: Peng
authors.forename: Zhong-dai
authors.initials: ZD
authors.lastname: Yuan
authors.forename: Chun-mei
authors.initials: CM
authors.lastname: Hu
authors.forename: Xing
authors.initials: X
authors.lastname: Yuan
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002944:Circumcision, Male; D003218:Condylomata Acuminata / Q000601:surgery*; D003475:Curettage / Q000379:methods*; D006801:Humans; D008297:Male; D008875:Middle Aged; D055815:Young Adult