title: Transposon Tn7 directs transposition into the genome of filamentous bacteriophage M13 using the element-encoded TnsE protein.
abstract: The bacterial transposon Tn7 has a pathway of transposition that preferentially targets conjugal plasmids. We propose that this same transposition pathway recognizes a structure or complex found during filamentous bacteriophage replication, likely by targeting negative-strand synthesis. The ability to insert into both plasmid and bacteriophage DNAs that are capable of cell-to-cell transfer would help explain the wide distribution of Tn7 relatives.
authors.affiliation: Department of Microbiology, Cornell University, Ithaca, NY 14853, USA.
authors.forename: Jessica A
authors.initials: JA
authors.lastname: Finn
authors.forename: Adam R
authors.initials: AR
authors.lastname: Parks
authors.forename: Joseph E
authors.initials: JE
authors.lastname: Peters
mesh_terms: D017104:Bacteriophage M13 / Q000235:genetics*; D004251:DNA Transposable Elements / Q000235:genetics*; D004268:DNA-Binding Proteins / Q000502:physiology*; D004926:Escherichia coli / Q000502:physiology / Q000821:virology; D029968:Escherichia coli Proteins / Q000502:physiology*; D016679:Genome, Viral; D010957:Plasmids / Q000235:genetics; D011995:Recombination, Genetic
chemical_list: D004251:DNA Transposable Elements; D004268:DNA-Binding Proteins; D029968:Escherichia coli Proteins; C424904:TnsE protein, E coli