title: Clinical efficiency and safety analysis of transcatheter interventional therapy for compound congenital cardiovascular abnormalities.
abstract: OBJECTIVE
  To investigate the efficiency and safety of transcatheter interventional therapy for compound congenital cardiovascular abnormalities.
  
  
  METHODS
  From Nov 2001 to Jun 2006, a total of 36 patients (17 male, 19 female), aged 17.20 +/- 10.52, with compound congenital cardiovascular abnormalities underwent transcatheter interventional procedure. These patients included 11 with perimembranous ventricular septal defect (PVSD) and patent ductus arteriosus (PDA), 8 patients with PVSD and atrial septal defect (ASD), 8 patients with ASD and PDA, 7 patients with ASD and pulmonary stenosis (PS), 1 patient with ASD and mitral stenosis(MS), 1 patient with coarctation of aorta (COA) and PDA. According to the principle of "easy first, hard second," balloon valvuloplasties of PS or MS were performed before the closure of PVSD, and of PDA and ASD. Electrocardiogram and transthoracic echocardiogram were examined at 4 days, 1, 2, 6 and 12 months, respectively, after each procedure.
  
  
  RESULTS
  Transcatheter interventional therapy for compound congenital cardiovascular abnormalities was successful in all patients. Among these, 2 occluders were planted in each of 27 patients, 7 patients with ASD combined with PS and 1 patient with ASD combined with MS underwent successfully performed balloon valvuloplasty and ASD closure, 1 patient with COA combined with PDA underwent successfully performed balloon valvuloplasty and subsequent covered stent implantation. No patient encountered serious adverse events during the (30.5 +/- 14.6) months of follow-up.
  
  
  CONCLUSIONS
  Transcatheter interventional therapy for compound congenital cardiovascular abnormalities could obtain satisfactory results with technical feasibility.
authors.affiliation: Department of Cardiology, Southwest Hospital, The Third Military Medical University, Chongqing, China. zysong@public.cta.cq.cn
authors.forename: Zhi-Yuan
authors.initials: ZY
authors.lastname: Song
authors.forename: Mao-Qin
authors.initials: MQ
authors.lastname: Shu
authors.forename: Hou-Yuan
authors.initials: HY
authors.lastname: Hu
authors.forename: Shi-Fei
authors.initials: SF
authors.lastname: Tong
authors.forename: Bo-Li
authors.initials: BL
authors.lastname: Ran
authors.forename: Jian-Pin
authors.initials: JP
authors.lastname: Liu
authors.forename: Yong-Hua
authors.initials: YH
authors.lastname: Li
authors.forename: Guo-Xiang
authors.initials: GX
authors.lastname: He
mesh_terms: D000293:Adolescent; D001017:Aortic Coarctation; D006328:Cardiac Catheterization / Q000009:adverse effects / Q000379:methods*; D005240:Feasibility Studies; D005260:Female; D006330:Heart Defects, Congenital / Q000628:therapy*; D006345:Heart Septal Defects, Ventricular; D006801:Humans; D008185:Lutembacher Syndrome; D008297:Male; D011446:Prospective Studies; D011666:Pulmonary Valve Stenosis