title: A case report of myocardial infarction in young patient with a parental history of premature cardiovascular death: combination of prothrombotic gene mutations.
abstract: We report a case of myocardial infarction at a young age in a subject heterozygous for the G20210A prothrombin gene variant and homozygous for the C677T MTHFR polymorphism, who presented a strong family history of atherothrombosis. Genetic screening for inherited thrombophilia, especially in the presence of a strong familiarity, may be a critical information for secondary prevention of arterial thrombosis.
authors.forename: Nicoletta
authors.initials: N
authors.lastname: Botto
authors.forename: Massimiliano
authors.initials: M
authors.lastname: Mariani
authors.forename: Samantha
authors.initials: S
authors.lastname: Manfredi
authors.forename: Maria Grazia
authors.initials: MG
authors.lastname: Andreassi
mesh_terms: D002318:Cardiovascular Diseases / Q000235:genetics*; D006801:Humans; D008487:Medical History Taking; D009154:Mutation; D009203:Myocardial Infarction / Q000235:genetics*; D010290:Parents; D013927:Thrombosis / Q000235:genetics*