title: Carotenoids and flavonoids contribute to nutritional protection against skin damage from sunlight.
abstract: The concept of photoprotection by dietary means is gaining momentum. Plant constituents such as carotenoids and flavonoids are involved in protection against excess light in plants and contribute to the prevention of UV damage in humans. As micronutrients, they are ingested with the diet and are distributed into light-exposed tissues, such as skin or the eye where they provide systemic photoprotection. beta-Carotene and lycopene prevent UV-induced erythema formation. Likewise, dietary flavanols exhibit photoprotection. After about 10-12 weeks of dietary intervention, a decrease in the sensitivity toward UV-induced erythema was observed in volunteers. Dietary micronutrients may contribute to life-long protection against harmful UV radiation.
authors.affiliation: Institut für Biochemie und Molekularbiologie I, Heinrich-Heine-Universität Düsseldorf, Dusseldorf 40001, Germany.
authors.forename: Wilhelm
authors.initials: W
authors.lastname: Stahl
authors.forename: Helmut
authors.initials: H
authors.lastname: Sies
mesh_terms: D002338:Carotenoids / Q000008:administration & dosage*; D004032:Diet; D004890:Erythema / Q000209:etiology / Q000517:prevention & control; D005419:Flavonoids / Q000008:administration & dosage*; D006801:Humans; D012867:Skin / Q000187:drug effects* / Q000528:radiation effects; D012871:Skin Diseases / Q000209:etiology / Q000517:prevention & control*; D013472:Sunlight / Q000009:adverse effects; D013473:Sunscreening Agents / Q000008:administration & dosage*
chemical_list: D005419:Flavonoids; D013473:Sunscreening Agents; D002338:Carotenoids