miRNAs play a tune.
Two new studies describe functionally relevant interactions between microRNAs (miRNAs) and their targets in the immune system and the brain (Xiao et al., 2007; Karres et al., 2007). Furthermore, these studies illustrate the involvement of miRNAs in tuning the expression of target genes to physiologically relevant levels.
Hobert
Oliver
O
Department of Biochemistry and Molecular Biophysics, Howard Hughes Medical Institute, Columbia University Medical Center, New York, NY 10032, USA. or38@columbia.edu
D001921:Brain / Q000502:physiology; D005786:Gene Expression Regulation; D007107:Immune System / Q000502:physiology; D035683:MicroRNAs / Q000235:genetics / Q000378:metabolism*
D035683:MicroRNAs