title: Biologically stable 2-5A analogues containing 3'-O,4'-C-bridged adenosine as potent RNase L agonists.
authors.affiliation: Exploratory Chemistry Research Laboratories, Sankyo Co., Ltd.,Tokyo 140-8710, Japan.
authors.forename: Koji
authors.initials: K
authors.lastname: Morita
authors.forename: Masakatsu
authors.initials: M
authors.lastname: Kaneko
authors.forename: Satoshi
authors.initials: S
authors.lastname: Obika
authors.forename: Takeshi
authors.initials: T
authors.lastname: Imanishi
authors.forename: Yukio
authors.initials: Y
authors.lastname: Kitade
authors.forename: Makoto
authors.initials: M
authors.lastname: Koizumi
mesh_terms: D000227:Adenine Nucleotides / Q000737:chemistry / Q000494:pharmacology*; D000241:Adenosine / Q000737:chemistry*; D004722:Endoribonucleases / Q000187:drug effects* / Q000378:metabolism; D004789:Enzyme Activation; D009843:Oligoribonucleotides / Q000737:chemistry / Q000494:pharmacology*
chemical_list: D000227:Adenine Nucleotides; D009843:Oligoribonucleotides; C023505:2',5'-oligoadenylate; D004722:Endoribonucleases; C031956:2-5A-dependent ribonuclease; D000241:Adenosine