Gold-catalyzed hydroarylation of allenes: a highly regioselective carbon-carbon bond formation producing six-membered rings.
Gold-catalyzed intramolecular hydroarylation of allenic anilines and phenols offers an efficient route to dihydroquinoline and chromene derivatives under mild reaction conditions. The hydroarylation takes place at the terminal or central allenic carbon depending on the substrate structure, leading to a highly selective formation of six-membered rings.
Watanabe
Toshiaki
T
Graduate School of Pharmaceutical Sciences, Kyoto University, Sakyo-ku, Kyoto 606-8501, Japan.
Oishi
Shinya
S
Fujii
Nobutaka
N
Ohno
Hiroaki
H
D000466:Alkadienes / Q000737:chemistry*; D002244:Carbon / Q000737:chemistry*; D002384:Catalysis; D003500:Cyclization; D006046:Gold / Q000737:chemistry*; D006571:Heterocyclic Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D006859:Hydrogen / Q000737:chemistry*; D015394:Molecular Structure
D000466:Alkadienes; D006571:Heterocyclic Compounds; C025947:propadiene; D002244:Carbon; D006046:Gold; D006859:Hydrogen