Elemental mass spectrometry for quantitative proteomics.
In the last decade mass-spectrometry-based proteomics has become an indispensable analytical tool for molecular biology, cellular biology and, lately, for the emerging systems biology. This review summarises the evolution and great potential of analytical methods based on elemental mass-spectrometric detection for quantitative proteomic analysis.
Sanz-Medel
Alfredo
A
Department of Physical and Analytical Chemistry, Faculty of Chemistry, University of Oviedo, C/Julián Clavería 8, 33006, Oviedo, Spain. asm@uniovi.es
Montes-Bayón
María
M
del Rosario Fernández de la Campa
María
M
Encinar
Jorge Ruiz
JR
Bettmer
Jörg
J
D002138:Calibration; D004602:Elements; D006801:Humans; D013058:Mass Spectrometry / Q000379:methods*; D011506:Proteins / Q000032:analysis / Q000737:chemistry; D040901:Proteomics / Q000379:methods*
D004602:Elements; D011506:Proteins