title: Collecting duct epithelium and injury: not all cells are created equal.
abstract: Studies by Butt et al. in the developing fetus provide new and timely insights into the regulation of repair and fibrosis in the injured kidney. Using a clinically relevant model, they have examined the response of the medullary collecting duct to ureteral obstruction, with some unexpected findings.
authors.affiliation: Department of Nephrology, Royal Melbourne Hospital, Melbourne, Victoria, Australia. tim.hewitson@mh.org.au
authors.forename: T D
authors.initials: TD
authors.lastname: Hewitson
mesh_terms: D000818:Animals; D051399:Aquaporin 2 / Q000378:metabolism; D024402:Carbonic Anhydrase II / Q000378:metabolism; D002450:Cell Communication / Q000502:physiology; D002454:Cell Differentiation / Q000502:physiology; D002465:Cell Movement / Q000502:physiology; D004195:Disease Models, Animal; D004847:Epithelial Cells / Q000378:metabolism / Q000473:pathology*; D005260:Female; D005355:Fibrosis; D007679:Kidney Medulla / Q000196:embryology / Q000378:metabolism / Q000473:pathology*; D007685:Kidney Tubules, Collecting / Q000196:embryology / Q000378:metabolism / Q000473:pathology*; D008253:Macaca mulatta; D008648:Mesoderm / Q000378:metabolism / Q000473:pathology*; D011247:Pregnancy; D014517:Ureteral Obstruction / Q000378:metabolism / Q000473:pathology
chemical_list: D051399:Aquaporin 2; D024402:Carbonic Anhydrase II