A remarkable accelerating effect of Ag-salt on intramolecular cyclization of o-(1-alkynyl)benzenesulfonamides.
Herein, we report transition metal-catalyzed intramolecular cyclization of o-(1-alkynyl)benzenesulfonamides to afford 3-substituted benzothiazines regioselectively via a C-N bond forming reaction and Cu-catalyzed sequential C-N and C-C bond formation leading to the corresponding 3,4-disubstituted derivatives.
Barange
Deepak Kumar
DK
Chemistry-Discovery Research, Dr. Reddy's Laboratories Ltd., Bollaram Road, Miyapur, Hyderabad 500049, India.
Nishad
T C
TC
Swamy
N Kumara
NK
Bandameedi
Venkanna
V
Kumar
Dinesh
D
Sreekanth
Bukkapattanam R
BR
Vyas
K
K
Pal
Manojit
M
D003300:Copper / Q000737:chemistry; D003500:Cyclization; D015394:Molecular Structure; D012492:Salts / Q000737:chemistry; D012834:Silver / Q000737:chemistry*; D013237:Stereoisomerism; D013449:Sulfonamides / Q000138:chemical synthesis* / Q000737:chemistry; D000096926:Benzenesulfonamides
D003300:Copper; D012492:Salts; D012834:Silver; D013449:Sulfonamides; D000096926:Benzenesulfonamides