title: Auto-inflammatory fever syndromes.
abstract: Human autoinflammatory diseases (except for PFAPA) are a heterogeneous group of genetically determined diseases characterized by seemingly unprovoked inflammation in the absence of autoimmune or infective causes (Table 2). The last decade has witnessed tremendous advances in the understanding of these disorders. These advances have allowed therapeutic interventions resulting in improvement in the short-term and long-term morbidity of all of these diseases. Future research into the molecular mechanisms underlying these inflammatory diseases should lead to a better understanding of inflammatory diseases in general and, it is hoped, to better and more targeted therapies.
authors.affiliation: Pediatric Rheumatology, Edmond & Lily Safra Children's Hospital, The Chaim Sheba Medical Center, Tel Hashomer 52621, Israel. padeh@012.net.il
authors.forename: Shai
authors.initials: S
authors.lastname: Padeh
authors.forename: Yakov
authors.initials: Y
authors.lastname: Berkun