Chemometric experimental design based optimization techniques in capillary electrophoresis: a critical review of modern applications.
A critical review of recent developments in the use of chemometric experimental design based optimization techniques in capillary electrophoresis applications is presented. Current advances have led to enhanced separation capabilities of a wide range of analytes in such areas as biological, environmental, food technology, pharmaceutical, and medical analysis. Significant developments in design, detection methodology and applications from the last 5 years (2002-2007) are reported. Furthermore, future perspectives in the use of chemometric methodology in capillary electrophoresis are considered.
Hanrahan
Grady
G
Department of Chemistry and Biochemistry, California State University, Los Angeles, Los Angeles, CA 90032, USA. ghanraha@clunet.edu
Montes
Ruthy
R
Gomez
Frank A
FA
D000383:Agriculture; D002623:Chemistry Techniques, Analytical; D004345:Drug Industry; D019075:Electrophoresis, Capillary / Q000379:methods*; D006801:Humans; D012107:Research Design