title: Serum anti-Müllerian hormone levels differentiate control from subfertile men but not men with different causes of subfertility.
abstract: OBJECTIVE
  To determine stimulated serum anti-Mllerian hormone (AMH) levels in men with different causes of subfertility.
  
  
  METHODS
  We prospectively studied 82 subfertile men and 31 controls. The subfertile men underwent a diagnostic procedure to identify the causes of subfertility. Study parameters included testicular volume, levels of follicle-stimulating hormone, luteinizing hormone, total testosterone, prolactin, inhibin B and AMH, and sperm parameters.
  
  
  RESULTS
  Clinical diagnoses in subfertile men were idiopathic non-obstructive azoospermia (n = 26, 32%), idiopathic non-obstructive dyspermia (n = 17, 21%), varicocele (n = 16, 20%), cryptorchidism (n = 10, 12%) and other diagnoses (n = 13, 16%). Serum AMH levels in subfertile men were 60% lower than in controls [median (interquartile range) 4.6 (3.6) vs. 11.6 (7.7) ng/ml, p 0.001], with no significant differences among the different groups of subfertile men.
  
  
  CONCLUSIONS
  Serum AMH levels differentiate control from subfertile men but not men with different causes of subfertility.
authors.affiliation: Unit of Reproductive Endocrinology, First Department of Obstetrics and Gynecology, Aristotle University of Thessaloniki, Thessaloniki, Greece. dimitrios.goulis@otenet.gr
authors.forename: Dimitrios G
authors.initials: DG
authors.lastname: Goulis
authors.forename: Paschalia K
authors.initials: PK
authors.lastname: Iliadou
authors.forename: Christos
authors.initials: C
authors.lastname: Tsametis
authors.forename: Spyridon
authors.initials: S
authors.lastname: Gerou
authors.forename: Basil C
authors.initials: BC
authors.lastname: Tarlatzis
authors.forename: Ioannis N
authors.initials: IN
authors.lastname: Bontis
authors.forename: Ioannis
authors.initials: I
authors.lastname: Papadimas
mesh_terms: D000328:Adult; D054304:Anti-Mullerian Hormone / Q000097:blood*; D053713:Azoospermia / Q000097:blood; D003456:Cryptorchidism / Q000150:complications; D006801:Humans; D007248:Infertility, Male / Q000097:blood* / Q000209:etiology*; D008297:Male; D011446:Prospective Studies; D013076:Sperm Count; D013081:Sperm Motility; D013094:Spermatozoa / Q000002:abnormalities; D014646:Varicocele / Q000150:complications
chemical_list: D054304:Anti-Mullerian Hormone