[Coagulopathy resulting from lupus anticoagulant antibodies as a paraneoplastic phenomenon in renal cell carcinoma relapse].
Lupus anticoagulant syndrome (LAS) is a form of coagulopathy with protracted PTT and an elevated risk of thromboembolic events, which occasionally occurs as a paraneoplastic phenomen in the presence of tumors. It is diagnosed by specific coagulation tests that identify lupus anticoagulant antibodies. We present the case of a 57-year-old woman with a coagulopathy caused by lupus anticoagulant antibodies as a paraneoplastic phenomenon in the course of a relapse of clear cell renal cell carcinoma in the area of the ipsilateral adrenal gland 18 months after tumor nephrectomy. After adrenalectomy with concomitant administration of low-molecular-weight heparin the PTT became normal and the diagnostic tests for lupus anticoagulant antibodies became negative.
Berdjis
N
N
Klinik für Urologie, Evangelisches Krankenhaus Johannesstift, Bielefeld, Deutschland. Navid.Berdjis@hotmail.com
Meier
M
M
Hoeppner
F
F
Behrendt
H
H
D002292:Carcinoma, Renal Cell / Q000175:diagnosis / Q000209:etiology*; D003937:Diagnosis, Differential; D004211:Disseminated Intravascular Coagulation / Q000097:blood / Q000150:complications* / Q000175:diagnosis*; D005260:Female; D006801:Humans; D007680:Kidney Neoplasms / Q000175:diagnosis* / Q000209:etiology*; D016682:Lupus Coagulation Inhibitor / Q000097:blood*; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis / Q000209:etiology*; D010257:Paraneoplastic Syndromes / Q000150:complications* / Q000175:diagnosis
D016682:Lupus Coagulation Inhibitor