title: Headache associated with miller fisher syndrome.
abstract: Miller Fisher syndrome, a variant of Guillain-Barre syndrome, is composed of the clinical triad of ophthalmoplegia, ataxia, and areflexia. A variety of other symptoms and signs have been reported in this syndrome, but headache is not a commonly reported symptom. We report a 35-year-old man with anti-GQ(1b) antibody-confirmed Miller Fisher syndrome presenting with severe and persistent headache, and we propose that the headache is caused by antibody-mediated effects on the trigeminovascular pain pathway.
authors.affiliation: University of Rochester - Ophthalmology & Neurology, Rochester, NY 14642, USA.
authors.forename: Deborah I
authors.initials: DI
authors.lastname: Friedman
authors.forename: Eric
authors.initials: E
authors.lastname: Potts
mesh_terms: D000328:Adult; D001323:Autoantibodies / Q000097:blood; D005732:Gangliosides / Q000276:immunology; D006261:Headache / Q000209:etiology* / Q000276:immunology / Q000503:physiopathology; D006801:Humans; D008297:Male; D019846:Miller Fisher Syndrome / Q000150:complications*; D012720:Severity of Illness Index
chemical_list: D001323:Autoantibodies; D005732:Gangliosides; C039129:GQ1b ganglioside