title: Outcomes of controlled ovarian hyperstimulation/in vitro fertilization for infertile patients with borderline ovarian tumor after conservative treatment.
abstract: To evaluate the outcomes of controlled ovarian hyperstimulation (COH)-in vitro fertilization (IVF) such as clinical pregnancy rate (CPR), implantation rate (IR) and live birth rate (LBR) for infertile patients with borderline ovarian tumor (BOT) after conservative treatment, 10 IVF cycles in five patients from January 1999 to July 2005 were analyzed. At the time of diagnosis with BOT, the mean age of patients was 30.0 yr (range, 22-40). For 8 cycles out of 10 attempted IVF cycles, except for 2 cancellation cycles, the mean number of oocytes retrieved was 5.6 (range, 2-16) with a mean fertilization rate of 74.4%. The CPR, IR, and LBR were 50.0% (4/8 cycles), 31.6% (6/19) and 50.0% (4/8 cycles) respectively. The mean follow-up period after COH-IVF initiation was 29.6 (range, 14-61) months. A gynecological oncologist followed all patients every 3 months during the first year and every 6 months thereafter. There was no recurrence during the follow-up period. Our results suggest that COH-IVF may be acceptable for infertile patients with BOT, especially in patients with early-stage BOT after conservative treatment.
authors.affiliation: Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Cheil General Hospital, Kwandong University College of Medicine, Seoul, Korea.
authors.forename: Chan Woo
authors.initials: CW
authors.lastname: Park
authors.forename: Kwang Moon
authors.initials: KM
authors.lastname: Yang
authors.forename: Hye Ok
authors.initials: HO
authors.lastname: Kim
authors.forename: Sung Ran
authors.initials: SR
authors.lastname: Hong
authors.forename: Tae Jin
authors.initials: TJ
authors.lastname: Kim
authors.forename: Kyung Taek
authors.initials: KT
authors.lastname: Lim
authors.forename: Ki Heon
authors.initials: KH
authors.lastname: Lee
authors.forename: Inn Soo
authors.initials: IS
authors.lastname: Kang
mesh_terms: D000328:Adult; D004624:Embryo Transfer; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D007247:Infertility, Female / Q000150:complications* / Q000628:therapy*; D010051:Ovarian Neoplasms / Q000150:complications* / Q000473:pathology / Q000601:surgery*; D010062:Ovulation Induction / Q000379:methods; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic; D011379:Prognosis; D016896:Treatment Outcome