title: [The older patient with malignant diseases].
abstract: Most malignancies show a steep increase of incidence with growing age. Because of this age specific incidence and the general aging of the population in western industrial countries the number of elderly cancer patients continuously and rapidly increases. Despite this development elderly cancer patients are currently underrepresented in clinical trials. This is caused in part by the lack of a common definition of the elderly patient and by the fact that a part of the elderly patients suffers from co-morbidities, not allowing a more dose intense treatment in these patients. It is one of the key current challenges to compensate this deficit and to develop therapeutic concepts specifically for the elderly patients, taking the individual somatic, but also social situation and finally the quality and perspective of life of the elderly patient into account.
authors.affiliation: Medizinische Klinik III, Klinikum der Universität München, Campus Grosshadern, Marchioninistrasse 15, 81377, München, Deutschland. Christian.Buske@med.uni-muenchen.de
authors.forename: C
authors.initials: C
authors.lastname: Buske
authors.forename: W
authors.initials: W
authors.lastname: Hiddemann
mesh_terms: D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D002986:Clinical Trials as Topic; D015897:Comorbidity; D003430:Cross-Sectional Studies; D015577:Geriatric Assessment; D005858:Germany; D006801:Humans; D015994:Incidence; D008017:Life Expectancy; D008875:Middle Aged; D009369:Neoplasms / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy*; D018579:Patient Selection; D011379:Prognosis