title: Access to vaccine technologies in developing countries: Brazil and India.
abstract: This study, conducted by visits, interviews, and literature search, analyzes how vaccine manufacturers in Brazil and India access technologies for innovative vaccines: through collaborations with academia and research institutions, technology transfer agreements with multinational corporations, public sector, or developing country organizations, or by importation and finishing of bulk products. Each has advantages and disadvantages in terms of speed, market, and ability to independently produce the product. Most manufacturers visited are very concerned about avoiding patent infringement, which might result in undeveloped or delayed products because of a lack of mastery of the patent landscape. Disregarding the patent picture could also threaten the market of a potential product. Although it is too soon to assess the effects of TRIPS on vaccine technology access in Brazil and India, a good understanding of intellectual property management will be useful. A case study on development of a new combination vaccine illustrates these findings.
authors.affiliation: University of Maryland School of Medicine, 3 bis rue des Coronilles, Résidence Parc de Clementville Bâtiment C, 34070 Montpellier, France. milstien@medicine.umaryland.edu
authors.forename: Julie B
authors.initials: JB
authors.lastname: Milstien
authors.forename: Patrick
authors.initials: P
authors.lastname: Gaulé
authors.forename: Miloud
authors.initials: M
authors.lastname: Kaddar
mesh_terms: D001938:Brazil; D003906:Developing Countries; D006801:Humans; D007194:India; D018973:Intellectual Property; D007391:International Cooperation; D018581:Technology Transfer; D014612:Vaccines / Q000191:economics / Q000600:supply & distribution*
chemical_list: D014612:Vaccines