title: Treatment of unprotected left main coronary artery stenosis in a 5-year-old heart transplant patient using a sirolimus-eluting stent.
abstract: Cardiac allograft vasculopathy is the most common cause of long-term graft failure in adult and pediatric heart transplant recipients. In the absence of a specific treatment for this condition, percutaneous revascularization has been the main palliative treatment in the adult population. Revascularization of pediatric patients, however, is more problematic secondary to the lack of a large pool of outcome data and the encounter of special technical challenges. We present the case of a 5-year-old girl who presented with severe cardiac allograft vasculopathy of her left main coronary artery and was treated with sirolimus stent placement.
authors.affiliation: Division of Cardiology, Department of Internal Medicine, Vanderbilt University, Nashville, Tennessee 37232, USA. joseph.g.salloum@vanderbilt.edu
authors.forename: Joseph G
authors.initials: JG
authors.lastname: Salloum
authors.forename: Debra A
authors.initials: DA
authors.lastname: Dodd
authors.forename: David
authors.initials: D
authors.lastname: Slosky
authors.forename: David X M
authors.initials: DX
authors.lastname: Zhao
mesh_terms: D002675:Child, Preschool; D017023:Coronary Angiography; D023921:Coronary Stenosis / Q000000981:diagnostic imaging / Q000209:etiology* / Q000628:therapy*; D016503:Drug Delivery Systems; D005260:Female; D016027:Heart Transplantation / Q000009:adverse effects*; D006801:Humans; D020123:Sirolimus / Q000008:administration & dosage*; D015607:Stents; D016896:Treatment Outcome
chemical_list: D020123:Sirolimus