title: Periosteal reaction in systemic lupus erythematosus.
abstract: Musculoskeletal complaints are the most common presenting symptoms in most of the patients with systemic lupus erythematosus (SLE). However, periosteal new bone formation is an extraordinarily rare condition in SLE. We report a case of periosteal reaction in SLE. A 31-year-old woman with SLE presented with both knee pain. Radiographs revealed periosteal reactions in both femur and tibia and around the metaphysis of the right distal tibia. Periosteal reaction can be caused by benign or malignant lesions and infection. We cannot find any other cause of periosteal reaction in our case after thorough evaluations. Periosteal reaction in SLE might be associated with inflammatory vascular changes. This is the first report of periosteal reaction in SLE after the 1990s description and the first report in Korea.
authors.affiliation: Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Ilwon-dong, Gangnam-gu, Seoul 135-710, Republic of Korea.
authors.forename: Joong Kyong
authors.initials: JK
authors.lastname: Ahn
authors.forename: You Sun
authors.initials: YS
authors.lastname: Lee
authors.forename: Hey Won
authors.initials: HW
authors.lastname: Chung
authors.forename: Hoon-Suk
authors.initials: HS
authors.lastname: Cha
authors.forename: Eun-Mi
authors.initials: EM
authors.lastname: Koh
mesh_terms: D000082:Acetaminophen / Q000627:therapeutic use; D000701:Analgesics, Opioid / Q000627:therapeutic use; D005260:Female; D005269:Femur / Q000000981:diagnostic imaging / Q000473:pathology; D006801:Humans; D007717:Knee / Q000503:physiopathology; D008180:Lupus Erythematosus, Systemic / Q000150:complications / Q000473:pathology* / Q000503:physiopathology; D010008:Osteochondritis Dissecans / Q000150:complications / Q000473:pathology / Q000503:physiopathology; D010012:Osteogenesis; D010146:Pain / Q000188:drug therapy / Q000503:physiopathology; D010521:Periosteum / Q000000981:diagnostic imaging / Q000473:pathology*; D011859:Radiography; D013977:Tibia / Q000000981:diagnostic imaging / Q000473:pathology; D014147:Tramadol / Q000627:therapeutic use
chemical_list: D000701:Analgesics, Opioid; D000082:Acetaminophen; D014147:Tramadol