title: Current challenges in autotransport and two-partner protein secretion pathways.
abstract: The two-partner and autotransport pathways are widely represented in Gram-negative bacteria, essentially among pathogens. Both mediate the translocation of large proteins across the outer membrane. Deciphering the molecular mechanisms of secretion machineries as well as folding of exoproteins in the course of translocation represents a current challenge.
authors.affiliation: INSERM U629, Institut Pasteur de Lille, IFR142, 1 Rue du Professeur Calmette, 59019 Lille Cedex, France.
authors.forename: Hélène
authors.initials: H
authors.lastname: Hodak
authors.forename: Françoise
authors.initials: F
authors.lastname: Jacob-Dubuisson
mesh_terms: D001426:Bacterial Proteins / Q000737:chemistry / Q000378:metabolism*; D001692:Biological Transport; D006090:Gram-Negative Bacteria / Q000378:metabolism*; D018832:Molecular Chaperones / Q000502:physiology; D019897:Periplasm / Q000378:metabolism; D017510:Protein Folding
chemical_list: D001426:Bacterial Proteins; D018832:Molecular Chaperones