Dramatic effects of ionic liquids on the palladium-catalyzed cyclocarbonylation of enynols with thiols.
Palladium-catalyzed carbonylation reactions of enynols with thiols in ionic liquids afford monocarbonylated 6-membered-ring lactones in high yields and good selectivity. These results are significantly different from those obtained when conducting the reaction in THF. The recyclability of the catalytic system was also investigated.
Cao
Hong
H
Centre for Catalysis Research and Innovation, Department of Chemistry, University of Ottawa, 10 Marie Curie, Ottawa, Ontario K1N 6N5, Canada.
Xiao
Wen-Jing
WJ
Alper
Howard
H
D000480:Alkynes / Q000737:chemistry*; D002384:Catalysis; D003500:Cyclization; D052578:Ionic Liquids / Q000737:chemistry*; D007783:Lactones / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D010165:Palladium / Q000737:chemistry*; D013237:Stereoisomerism; D013438:Sulfhydryl Compounds / Q000737:chemistry*
D000480:Alkynes; D052578:Ionic Liquids; D007783:Lactones; D013438:Sulfhydryl Compounds; D010165:Palladium