title: A large sellar granular cell tumor in a 21-year-old woman.
abstract: We report here the case of a 21-year-old woman with a large sellar tumor, extending to the suprasellar area associated with growth hormone deficiency, hypogonadism, hypocorticism, and hyperprolactinemia. Transsphenoidal surgery was performed, and histologic, immunohistochemical, and electron microscopic study lead to the diagnosis of granular cell tumor. These tumors are, in most cases, very small and are found incidentally at autopsy of older patients. Our case is exceptional because the tumor developed in a young woman, extended to the suprasellar region, and caused clinical symptoms.
authors.affiliation: University Clinical Center, Neuroendocrine Unit, Institute of Endocrinology, Dr. Subotica 13, Belgrade, 11000, Serbia. popver@eunet.yu
authors.forename: Vera
authors.initials: V
authors.lastname: Popovic
authors.forename: Sandra
authors.initials: S
authors.lastname: Pekic
authors.forename: Milica
authors.initials: M
authors.lastname: Skender-Gazibara
authors.forename: Fateme
authors.initials: F
authors.lastname: Salehi
authors.forename: Kalman
authors.initials: K
authors.lastname: Kovacs
mesh_terms: D000328:Adult; D000568:Amenorrhea / Q000209:etiology; D005260:Female; D016586:Granular Cell Tumor / Q000473:pathology*; D006261:Headache / Q000209:etiology; D006728:Hormones / Q000097:blood; D019382:Human Growth Hormone / Q000172:deficiency; D006801:Humans; D007006:Hypogonadism / Q000209:etiology; D007150:Immunohistochemistry; D008279:Magnetic Resonance Imaging; D046529:Microscopy, Electron, Transmission; D010901:Pituitary Function Tests; D010911:Pituitary Neoplasms / Q000473:pathology*; D012658:Sella Turcica / Q000473:pathology*; D014786:Vision Disorders / Q000209:etiology
chemical_list: D006728:Hormones; D019382:Human Growth Hormone