Serum anti-Müllerian hormone levels differentiate control from subfertile men but not men with different causes of subfertility.
OBJECTIVE
To determine stimulated serum anti-Mllerian hormone (AMH) levels in men with different causes of subfertility.


METHODS
We prospectively studied 82 subfertile men and 31 controls. The subfertile men underwent a diagnostic procedure to identify the causes of subfertility. Study parameters included testicular volume, levels of follicle-stimulating hormone, luteinizing hormone, total testosterone, prolactin, inhibin B and AMH, and sperm parameters.


RESULTS
Clinical diagnoses in subfertile men were idiopathic non-obstructive azoospermia (n = 26, 32%), idiopathic non-obstructive dyspermia (n = 17, 21%), varicocele (n = 16, 20%), cryptorchidism (n = 10, 12%) and other diagnoses (n = 13, 16%). Serum AMH levels in subfertile men were 60% lower than in controls [median (interquartile range) 4.6 (3.6) vs. 11.6 (7.7) ng/ml, p 0.001], with no significant differences among the different groups of subfertile men.


CONCLUSIONS
Serum AMH levels differentiate control from subfertile men but not men with different causes of subfertility.
Goulis
Dimitrios G
DG
Unit of Reproductive Endocrinology, First Department of Obstetrics and Gynecology, Aristotle University of Thessaloniki, Thessaloniki, Greece. dimitrios.goulis@otenet.gr
Iliadou
Paschalia K
PK
Tsametis
Christos
C
Gerou
Spyridon
S
Tarlatzis
Basil C
BC
Bontis
Ioannis N
IN
Papadimas
Ioannis
I
D000328:Adult; D054304:Anti-Mullerian Hormone / Q000097:blood*; D053713:Azoospermia / Q000097:blood; D003456:Cryptorchidism / Q000150:complications; D006801:Humans; D007248:Infertility, Male / Q000097:blood* / Q000209:etiology*; D008297:Male; D011446:Prospective Studies; D013076:Sperm Count; D013081:Sperm Motility; D013094:Spermatozoa / Q000002:abnormalities; D014646:Varicocele / Q000150:complications
D054304:Anti-Mullerian Hormone