title: A new HLA-B*15 variant - B*9507.
abstract: The human leukocyte antigen-B*15 variant B*9507 is similar to B*1505 (B62) but with substitutions of A>C at position 463 and G>C at position 477 in exon 3. This results in a single amino acid change of serine to arginine (AGC>CGC) at codon 131 and a silent substitution (GCG>GCC - conserved alanine) at codon 135.
authors.affiliation: Welsh Transplantation and Immunogenetics Laboratory, Welsh Blood Service, Wales, UK.
authors.forename: L
authors.initials: L
authors.lastname: Hammond
authors.forename: J
authors.initials: J
authors.lastname: Street
authors.forename: J
authors.initials: J
authors.lastname: Johnson
authors.forename: J
authors.initials: J
authors.lastname: Pepperall
authors.forename: C
authors.initials: C
authors.lastname: Darke
mesh_terms: D000483:Alleles; D019943:Amino Acid Substitution; D014644:Genetic Variation; D015235:HLA-B Antigens / Q000235:genetics*; D059910:HLA-B15 Antigen; D006801:Humans; D016133:Polymerase Chain Reaction
chemical_list: D015235:HLA-B Antigens; C528711:HLA-B*15:107 antigen; D059910:HLA-B15 Antigen