title: The Patient Card questionnaire to identify wearing-off in Parkinson disease.
abstract: This study sought to evaluate the feasibility and performance of the Patient Card (PC), an instrument derived from the Patient Questionnaire by Stacy et al, for detection of wearing-off (W-O), in a very first application to a Spanish population with Parkinson disease. Patients were classified as experiencing W-O on the basis of the clinician's Follow-up Questionnaire, the Unified Parkinson Disease Rating Scale-Item 36, or improvement, after the following scheduled dose of medication, of 1 or more symptoms included in the PC. The highest proportion of patients with W-O was identified by the PC (79.8%), followed by the Follow-up Questionnaire (55.4%), and Unified Parkinson Disease Rating Scale (35.1%) (Cochran Q, P < 0.01). The PC Spanish version performed adequately, capturing W-O symptoms more frequently than did the other methods, as in the original Patient Questionnaire study by Stacy et al. Accordingly, the PC may potentially help clinicians identify W-O phenomena and thereby allow for better management of patients with Parkinson disease.
authors.affiliation: Neuroepidemiology Unit, National Center for Epidemiology, Carlos III Institute of Health, C/.Sinesio Delgado 6, 28029 Madrid, Spain. pmartinez@isciii.es
authors.forename: Pablo
authors.initials: P
authors.lastname: Martínez-Martín
authors.forename: Eduardo
authors.initials: E
authors.lastname: Tolosa
authors.forename: Basilio
authors.initials: B
authors.lastname: Hernández
authors.forename: Xavier
authors.initials: X
authors.lastname: Badia
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003072:Cognition Disorders / Q000209:etiology; D003430:Cross-Sectional Studies; D004185:Disability Evaluation; D004409:Dyskinesia, Drug-Induced; D005221:Fatigue / Q000209:etiology; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D017063:Outcome Assessment, Health Care; D010300:Parkinson Disease / Q000503:physiopathology*; D012720:Severity of Illness Index; D013030:Spain / Q000453:epidemiology; D011795:Surveys and Questionnaires