title: [Frequencies of GSTM1, GSTT1, and GSTP1 polymorphisms in ethnic minority from Guizhou].
abstract: OBJECTIVE
  To investigate the frequencies of GSTM1, GSTT1 and GSTP1 polymorphisms in Dong, Yi and Yao ethnic groups from Guizhou.
  
  
  METHODS
  In 321 volunteers who were population-based, GSTM1 and GSTT1 polymorphisms were analyzed by a multiplex-PCR procedure, whereas GSTP1 polymorphism was analyzed by PCR-RFLP method.
  
  
  RESULTS
  Null genotype for GSTM1 and GSTT1 was 59.6%-71.2% and 39.4%-72.5%, respectively. The genotypic distribution of GSTP1 was 63.3%-75% for AA, 23.2%-35.8% for AG, 0-1.9% for GG, whereas the allelic frequencies were 81.2%-86.6% for the A allele, and 13.4%-18.8% for the G allele.
  
  
  CONCLUSIONS
  There is a significant relationship between GSTT1 frequencies and ethnic populations.
authors.affiliation: The Key Lab of Molecular Biology, Guiyang Medical College, Guiyang, Guizhou, 550004 PR China.
authors.forename: Wei
authors.initials: W
authors.lastname: Zhang
authors.forename: Ke-ren
authors.initials: KR
authors.lastname: Shan
authors.forename: Chang-xue
authors.initials: CX
authors.lastname: Wu
authors.forename: Yi
authors.initials: Y
authors.lastname: Li
authors.forename: Yan
authors.initials: Y
authors.lastname: Xiao
authors.forename: Yan
authors.initials: Y
authors.lastname: Zhao
authors.forename: Xiao-lan
authors.initials: XL
authors.lastname: Qi
authors.forename: Yuan
authors.initials: Y
authors.lastname: Xie
authors.forename: Yan
authors.initials: Y
authors.lastname: He
authors.forename: Ran
authors.initials: R
authors.lastname: Gu
authors.forename: Zhi-zhong
authors.initials: ZZ
authors.lastname: Guan
authors.forename: Xi-lin
authors.initials: XL
authors.lastname: Ren
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D044466:Asian People / Q000235:genetics; D002681:China / Q000208:ethnology; D005006:Ethnicity / Q000235:genetics*; D005260:Female; D005787:Gene Frequency / Q000235:genetics*; D005838:Genotype; D051549:Glutathione S-Transferase pi / Q000235:genetics; D005982:Glutathione Transferase / Q000235:genetics*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009154:Mutation; D011110:Polymorphism, Genetic
chemical_list: D051549:Glutathione S-Transferase pi; D005982:Glutathione Transferase; C413545:glutathione S-transferase T1; C496556:GSTP1 protein, human