title: Lemierre's syndrome with septic shock caused by Fusobacterium necrophorum.
abstract: Fusobacterium necrophorum infections are rare. We report a 15-year-old male who presented with tachycardia, nausea, vomiting, diarrhoea and ankle pain. He rapidly deteriorated requiring ventilation and vasopressors. Imaging of his thorax showed airspace consolidation, pulmonary cavitations and empyema. The ankle required drainage of purulent material. A thrombus in his internal jugular vein (Lemierre's syndrome) and an abscess in his obturator internus were subsequently found. Fusobacterium necrophorum was identified in blood culture on day nine. The patient recovered with antibiotics and surgical interventions for empyema and septic arthritis. Fusobacterium necrophorum should be a suspected pathogen in septic shock complicated by metastatic abscess formation.
authors.affiliation: Children's Hospital of Western Ontario, University of Western Ontario, Schulich School of Medicine, London, Ontario, Canada.
authors.forename: D
authors.initials: D
authors.lastname: Wang
authors.forename: A K
authors.initials: AK
authors.lastname: Price
authors.forename: K K
authors.initials: KK
authors.lastname: Leitch
authors.forename: M
authors.initials: M
authors.lastname: Salvadori
authors.forename: R N
authors.initials: RN
authors.lastname: Singh
authors.forename: A
authors.initials: A
authors.lastname: Kornecki
authors.forename: S D
authors.initials: SD
authors.lastname: McKillop
authors.forename: D D
authors.initials: DD
authors.lastname: Fraser
mesh_terms: D000293:Adolescent; D003937:Diagnosis, Differential; D005674:Fusobacterium Infections / Q000188:drug therapy; D005675:Fusobacterium necrophorum; D006801:Humans; D007601:Jugular Veins; D008279:Magnetic Resonance Imaging; D008297:Male; D010612:Pharyngitis / Q000150:complications; D012772:Shock, Septic / Q000188:drug therapy / Q000382:microbiology*; D013577:Syndrome; D013924:Thrombophlebitis / Q000382:microbiology* / Q000473:pathology / Q000628:therapy