Vitamin A and E tissue distribution with comparisons to organochlorine concentrations in the serum, blubber and liver of the bowhead whale (Balaena mysticetus).
Vitamin A and E concentrations were determined in liver (n=51), blubber (n=23) and serum (n=53) of subsistence-hunted bowhead whales (Balaena mysticetus), between 1998 and 2001. Retinol and alpha-tocopherol were the major forms of vitamins A and E detected, respectively. Liver contained the highest mean concentrations of vitamin A, followed by epidermis, blubber, and serum. Liver also contained the highest mean concentration of vitamin E, followed by serum, epidermis, and blubber. Stratification of retinol and tocopherol was examined throughout the blubber cores collected. Retinol concentrations were significantly higher in the epidermis than in the deeper blubber layers. Tocopherol concentrations were similar for epidermis and the intermediate layer of blubber. Both the epidermis and the intermediate layer of blubber had significantly higher tocopherol concentrations than the innermost and outermost blubber layers. Vitamin A and E concentrations were investigated with respect to gender and reproductive status of females (males, non-pregnant females, pregnant females), age groups and season of harvest. Certain persistent organic contaminants are known to have a negative effect on retinol concentration in serum of pinnipeds and cetaceans. Bowhead whales have relatively low concentrations of organochlorines (OCs) in comparison to other mysticete species. The relationships between serum, liver and blubber retinol and serum and blubber OC concentrations were examined with no significant correlations noted.
Rosa
Cheryl
C
Institute of Arctic Biology, University of Alaska Fairbanks, 311 Irving I Building, Fairbanks, AK 99775, USA. Cheryl.Rosa@north-slope.org <Cheryl.Rosa@north-slope.org>
Blake
John E
JE
Mazzaro
Lisa
L
Hoekstra
Paul
P
Ylitalo
Gina M
GM
O'Hara
Todd M
TM
D000367:Age Factors; D000818:Animals; D050642:Bowhead Whale / Q000378:metabolism*; D004817:Epidermis / Q000737:chemistry; D005260:Female; D006843:Hydrocarbons, Chlorinated / Q000032:analysis* / Q000097:blood*; D050356:Lipid Metabolism / Q000187:drug effects; D008099:Liver / Q000737:chemistry*; D008297:Male; D011247:Pregnancy; D012098:Reproduction; D012621:Seasons; D012727:Sex Characteristics; D050151:Subcutaneous Fat / Q000737:chemistry*; D014018:Tissue Distribution / Q000187:drug effects; D014801:Vitamin A / Q000032:analysis* / Q000097:blood; D014810:Vitamin E / Q000032:analysis* / Q000097:blood; D014874:Water Pollutants, Chemical / Q000494:pharmacology
D006843:Hydrocarbons, Chlorinated; D014874:Water Pollutants, Chemical; D014801:Vitamin A; D014810:Vitamin E