Chronic intestinal pseudo-obstruction in patients with systemic lupus erythematosus: report of four cases.
Chronic intestinal pseudo-obstruction (CIPO), a recently recognized manifestation of systemic lupus erythematosus (SLE) with only 23 cases reported in the English literature, may appear as a complication or as the initial presentation of SLE and usually occurs during the setting of an active lupus. The pathogenic mechanism in SLE is unknown. We describe four additional cases with clinical, radiological, and manometric features of CIPO. As SLE-related CIPO usually responds to treatment with high doses of corticosteroids and/or immunosuppressive and prokinetic agents, a high level of awareness of this complication is needed to avoid unnecessary surgical intervention.
Ceccato
Federico
F
Rheumatology Section, Hospital JM Cullen, Santa Fe, Argentina.
Salas
Adrián
A
Góngora
Vanina
V
Ruta
Santiago
S
Roverano
Susana
S
Marcos
Juan Carlos
JC
Garcìa
Mercedes
M
Paira
Sergio
S
D000328:Adult; D000893:Anti-Inflammatory Agents / Q000009:adverse effects*; D005260:Female; D005765:Gastrointestinal Agents / Q000627:therapeutic use*; D006801:Humans; D007418:Intestinal Pseudo-Obstruction / Q000150:complications* / Q000188:drug therapy / Q000276:immunology; D008180:Lupus Erythematosus, Systemic / Q000150:complications* / Q000188:drug therapy; D008875:Middle Aged
D000893:Anti-Inflammatory Agents; D005765:Gastrointestinal Agents