title: [Photodynamic therapy in treatment of chorioid neovascularization].
abstract: The authors studied the effectiveness of photodynamic therapy (PDT) with Photosence, a Russian photosensitizer, in treatment of chorioid neovascularization (CNV) in cases of age-related macular degeneration (ARMD) and pathological myopia (PM). The subjects were 73 patients with CNV suffering from ARMD and PM. The efficiency of PDT and complex conservative therapy was compared using vision acuity measurement, retinal morphometry, and fluorescent eye ground angiography (FEGA), performed before treatment, immediately after treatment, and 1, 3, 6, and 12 months later. The study showed that PDT in patients with CNV, ARMD and PM was more efficient than pharmacotherapy. Vision acuity improved or stabilized, and the parameters of retinal morphometry and FEGA improved as well. The results of the study evidence high efficiency of PDT with Photosence in treatment of CNV with ARMD and PM.
authors.forename: S E
authors.initials: SE
authors.lastname: Avetisov
authors.forename: M V
authors.initials: MV
authors.lastname: Budzinskaia
authors.forename: T N
authors.initials: TN
authors.lastname: Kiseleva
authors.forename: E E
authors.initials: EE
authors.lastname: Kazarian
authors.forename: I V
authors.initials: IV
authors.lastname: Gurova
authors.forename: V B
authors.initials: VB
authors.lastname: Loshchenov
authors.forename: S A
authors.initials: SA
authors.lastname: Shevchik
authors.forename: S G
authors.initials: SG
authors.lastname: Kuz'min
authors.forename: G N
authors.initials: GN
authors.lastname: Vorozhtsov
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D020256:Choroidal Neovascularization / Q000188:drug therapy* / Q000473:pathology; D005451:Fluorescein Angiography; D005500:Follow-Up Studies; D005654:Fundus Oculi; D006801:Humans; D007211:Indoles / Q000008:administration & dosage / Q000627:therapeutic use*; D007275:Injections, Intravenous; D008875:Middle Aged; D009942:Organometallic Compounds / Q000008:administration & dosage / Q000627:therapeutic use*; D010778:Photochemotherapy / Q000379:methods*; D011838:Radiation-Sensitizing Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D041623:Tomography, Optical Coherence; D016896:Treatment Outcome
chemical_list: D007211:Indoles; D009942:Organometallic Compounds; D011838:Radiation-Sensitizing Agents; C048577:aluminum tetrasulfophthalocyanine