Coronary stent implantation may seal the inflammatory response in patients with acute coronary syndromes.
The change in CD40L levels before and 24 h coronary stenting was compared in patients presenting with acute coronary syndromes and for elective angioplasty. Baseline CD40L levels were lower in stable subjects, whereas unstable patients had a significant decrease of CD40L after stenting. This might suggest that coronary stenting, despite of being a local therapy, can help to seal a systemic inflammatory response in acute coronary syndromes.
Wainstein
Marco V
MV
Bento da Silva
Diego P
DP
Ribeiro
Jorge P
JP
D054058:Acute Coronary Syndrome / Q000276:immunology* / Q000628:therapy*; D015906:Angioplasty, Balloon, Coronary; D015415:Biomarkers / Q000097:blood*; D023201:CD40 Ligand / Q000097:blood; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015607:Stents
D015415:Biomarkers; D023201:CD40 Ligand