title: Antibiotic-loaded cement articulating spacer for 2-stage reimplantation in infected total knee arthroplasty: a simple and economic method.
abstract: We presented a simple and economic method of preparing articulating antibiotic-loaded cement spacers for treatment of infection after total knee arthroplasty. From 1996 to 2004, 28 infected total knee arthroplasties were treated with 2-stage reimplantation. Static spacers were used in 7 knees, and articulating spacers were used in 21 knees. A minimum of 2 years' follow-up after final treatment was evaluated. In the static group, 1 (14%) knee had recurrence of infection. In the articulating group, 2 (9%) knees had recurrence of infection with the original organism. Patients receiving articulating spacer had better range of motion, better knee score, and less bone loss than patients with static spacer.
authors.affiliation: Department of Orthopaedics and Traumatology, United Christian Hospital, The University of Hong Kong, Pokfulam, Hong Kong SAR, China.
authors.forename: Y C
authors.initials: YC
authors.lastname: Hsu
authors.forename: H C
authors.initials: HC
authors.lastname: Cheng
authors.forename: T P
authors.initials: TP
authors.lastname: Ng
authors.forename: K Y
authors.initials: KY
authors.lastname: Chiu
mesh_terms: D000900:Anti-Bacterial Agents / Q000009:adverse effects / Q000191:economics / Q000627:therapeutic use*; D001172:Arthritis, Rheumatoid / Q000601:surgery; D019645:Arthroplasty, Replacement, Knee / Q000009:adverse effects* / Q000191:economics / Q000379:methods; D001424:Bacterial Infections / Q000188:drug therapy / Q000191:economics / Q000209:etiology*; D001843:Bone Cements / Q000009:adverse effects / Q000191:economics / Q000627:therapeutic use*; D005500:Follow-Up Studies; D006801:Humans; D007592:Joint Diseases / Q000191:economics / Q000382:microbiology / Q000601:surgery; D007719:Knee Joint / Q000382:microbiology* / Q000502:physiology / Q000601:surgery; D020370:Osteoarthritis, Knee / Q000601:surgery; D016459:Prosthesis-Related Infections / Q000188:drug therapy*; D016059:Range of Motion, Articular / Q000502:physiology; D012008:Recurrence; D012086:Reoperation / Q000191:economics / Q000379:methods; D012189:Retrospective Studies; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents; D001843:Bone Cements