title: [Restless legs syndrome. Definition, cause and treatment].
abstract: Restless legs syndrome (RLS) is a common disorder affecting more than 2% of adults. RLS is characterized by sensory-motor phenomena predominantly in the legs, but other body parts may be involved. The symptoms are most pronounced during rest and present a characteristic diurnal variation with maximum symptoms in the evening and at night. The disease is often associated with periodic limb movements. RLS is present in an idiopathic and secondary form due to medical and other neurological diseases. Iron and DOPA are involved in the pathogenesis of the disease. The current best-documented treatment is partial dopamine-agonists and gabapentin.
authors.affiliation: Glostrup Hospital, Klinisk-neurofysiologisk Afdeling, Dansk Center for Søvnmedicin. jennum@dadlnet.dk
authors.forename: Poul Jørgen
authors.initials: PJ
authors.lastname: Jennum
mesh_terms: D000328:Adult; D000978:Antiparkinson Agents / Q000627:therapeutic use; D003937:Diagnosis, Differential; D018491:Dopamine Agonists / Q000627:therapeutic use; D006801:Humans; D012148:Restless Legs Syndrome / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology / Q000628:therapy
chemical_list: D000978:Antiparkinson Agents; D018491:Dopamine Agonists