title: A novel biotransformation of 2-formyl-6-naphthoic acid to 2,6-naphthalene dicarboxylic acid by Pseudomonas sp. for the purification of crude 2,6-naphthalene dicarboxylic acid.
abstract: Crude 2,6-naphthalene dicarboxylic acid was purified by Pseudomonas sp. HN-72 which biotransformed the major impurity of 2-formyl-6-naphthoic acid into 2,6-naphthalene dicarboxylic acid. The biotransformation yield reached 100% when the reaction was performed at 40 degrees C for 1 h, in 200 ml KH(2)PO(4)/KOH buffer (50 mM, pH 8.0), with 0.2% (w/v) crude 2,6-naphthalene dicarboxylic acid and 2.5 mg dry cell wt/ml.
authors.affiliation: R&D Business Labs, Hyosung Corporation, Anyang-Si, Gyeonggi-Do 431-080, Korea. ehdtjd9233@hanmail.net
authors.forename: Dong-Sung
authors.initials: DS
authors.lastname: Kim
authors.forename: Sung-Kyoon
authors.initials: SK
authors.lastname: Kim
authors.forename: Yong-Bok
authors.initials: YB
authors.lastname: Choi
authors.forename: Ik-Hyeon
authors.initials: IH
authors.lastname: Kwon
authors.forename: Kwan-Hwa
authors.initials: KH
authors.lastname: Park
mesh_terms: D002264:Carboxylic Acids / Q000737:chemistry*; D003998:Dicarboxylic Acids / Q000737:chemistry* / Q000302:isolation & purification*; D008401:Gas Chromatography-Mass Spectrometry; D009281:Naphthalenes / Q000737:chemistry* / Q000302:isolation & purification*; D011549:Pseudomonas / Q000737:chemistry / Q000302:isolation & purification* / Q000378:metabolism*
chemical_list: C528312:2-formyl-6-naphthoic acid; D002264:Carboxylic Acids; D003998:Dicarboxylic Acids; D009281:Naphthalenes; C109064:2,6-naphthalenedicarboxylic acid