Task-induced activation and hemispheric dominance in cerebral circulation during gum chewing.
In elderly persons, it is thought that maintenance of masticatory function may have a beneficial effect on maintenance of cerebral function. However, few studies on cerebral circulation during mastication exist. This study aimed to verify a possible increase in cerebral circulation and the presence of cerebral hemispheric dominance during gum chewing. Twelve healthy, young right-handed subjects with normal dentition were enrolled. Bilateral middle cerebral arterial blood flow velocities (MCAV), heart rate, and arterial carbon dioxide levels were measured during a handgrip exercise and gum chewing. During gum chewing, electromyography of the bilateral masseter muscle was recorded.MCAV and heart rate significantly increased during exercise compared to values at rest. During gum chewing, there were no differences in the rate of increase in MCAV between the working and non-working sides, but during the handgrip exercise, the rate of increase in MCAV was significantly greater for the non-working side than for the working side. During gum chewing,muscle activity on the working side was significantly greater than that on the non-working side. These results suggest that during gum chewing, cerebral circulation increases bilaterally and does not show contralateral dominance, as it does during the handgrip exercise.
Ono
T
T
Division of Oromaxillofacial Regeneration, Course of Integrated Oral Science, Osaka University Graduate School of Dentistry, Osaka, Japan. ono@dent.osaka-u.ac.jp
Hasegawa
Y
Y
Hori
K
K
Nokubi
T
T
Hamasaki
T
T
D000328:Adult; D001783:Blood Flow Velocity / Q000502:physiology; D002245:Carbon Dioxide / Q000378:metabolism; D002560:Cerebrovascular Circulation / Q000502:physiology*; D002638:Chewing Gum; D004576:Electromyography / Q000379:methods; D005260:Female; D007839:Functional Laterality; D018737:Hand Strength / Q000502:physiology; D006339:Heart Rate / Q000502:physiology; D006801:Humans; D008297:Male; D008406:Masseter Muscle / Q000502:physiology; D008409:Mastication / Q000502:physiology*; D020768:Middle Cerebral Artery / Q000000981:diagnostic imaging / Q000378:metabolism / Q000502:physiology; D017585:Ultrasonography, Doppler, Transcranial / Q000379:methods
D002638:Chewing Gum; D002245:Carbon Dioxide