title: Resectability of pancreatic adenocarcinoma: assessment using multidetector-row computed tomography with multiplanar reformations.
abstract: The purpose was to assess capabilities of the multidetector-row computed tomography (MDCT) with multiplanar reformations (MPR) for predicting of pancreatic adenocarcinoma resectability. Forty-eight patients deemed to have resectable pancreatic adenocarcinoma after assessment using biphasic MDCT with MPRs underwent surgery for potential tumor resection. Imaging findings were retrospectively evaluated for tumor resectability and correlated with surgical and pathological results. Curative resection was successful in 44 of 48 patients. The positive predictive value for tumor resectability made up 91% with four false-negative results. The reasons for unresectability were venous involvement (1), small liver metastases (2) and peritoneal involvement associated with small metastases to lymph nodes (1). MDCT yielded a negative predictive value of 99% (286 of 288 vessels) for detection of vascular invasion. Our results indicate the tendency towards improved prediction of resectability using MDCT compared to single-detector CT.
authors.affiliation: Institute for Diagnostic Radiology, Friedrich-Alexander University of Erlangen-Nuremberg, Erlangen, Germany. elenamanak@web.de
authors.forename: Elena
authors.initials: E
authors.lastname: Manak
authors.forename: Susanne
authors.initials: S
authors.lastname: Merkel
authors.forename: Peter
authors.initials: P
authors.lastname: Klein
authors.forename: Thomas
authors.initials: T
authors.lastname: Papadopoulos
authors.forename: Werner A
authors.initials: WA
authors.lastname: Bautz
authors.forename: Ulrich
authors.initials: U
authors.lastname: Baum
mesh_terms: D000230:Adenocarcinoma / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003287:Contrast Media; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009362:Neoplasm Metastasis; D010190:Pancreatic Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D016577:Pancreaticoduodenectomy; D011237:Predictive Value of Tests; D014057:Tomography, X-Ray Computed / Q000379:methods*; D016896:Treatment Outcome
chemical_list: D003287:Contrast Media