Outcome after hepatic resection of solitary liver metastasis from colorectal cancer in the caudate lobe.
BACKGROUND
The prognosis of solitary liver metastasis involving the caudate lobe is unclear. This study analyzed the outcomes after resection of the caudate lobe for solitary colorectal liver metastasis.


METHODS
We reviewed the records of 114 cases in which potentially curative hepatectomy were performed for solitary colorectal liver metastasis. Solitary liver metastasis involving the caudate lobe was seen in 14 cases (Caudate group). The outcomes were compared with those of the remaining 100 cases with metastasis in a site other than the caudate lobe (Other group).


RESULTS
No hospital deaths occurred. The 5-year survival rate for all cases was 61%. Recurrence-free and cumulative survivals were similar in the two groups, as were the intraoperative blood loss, duration of operation, and postoperative hospital stay. The distance of the surgical margin was significantly shorter in the Caudate group than in the Other group (0.6 mm vs. 6.6 mm; p = 0.001). A concomitant resection of the inferior vena cava was performed in four patients in the Caudate group but in no patients in the Other group (p < 0.001).


CONCLUSIONS
Despite a minimal surgical margin, the resection of solitary colorectal liver metastasis offers favorable short- and long-term outcomes comparable to those for colorectal liver metastasis at other sites.
Saiura
Akio
A
Department of Gastrointestinal Surgery, Cancer Institute Hospital, Tokyo, Japan. akio.saiura@jfcr.or.jp
Yamamoto
Junji
J
Koga
Rintaro
R
Kokudo
Norihiro
N
Seki
Makoto
M
Oya
Masatoshi
M
Ueno
Masashi
M
Kuroyanagi
Hiroya
H
Fujimoto
Yoshiya
Y
Natori
Takeshi
T
Yamaguchi
Toshiharu
T
Muto
Tetsuichiro
T
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015179:Colorectal Neoplasms / Q000473:pathology*; D005260:Female; D006498:Hepatectomy; D006801:Humans; D053208:Kaplan-Meier Estimate; D008113:Liver Neoplasms / Q000556:secondary* / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D016896:Treatment Outcome