Corticothalamic projections control synchronization in locally coupled bistable thalamic oscillators.
Thalamic circuits are able to generate state-dependent oscillations of different frequencies and degrees of synchronization. However, little is known about how synchronous oscillations, such as spindle oscillations in the thalamus, are organized in the intact brain. Experimental findings suggest that the simultaneous occurrence of spindle oscillations over widespread territories of the thalamus is due to the corticothalamic projections, as the synchrony is lost in the decorticated thalamus. In this Letter we study the influence of corticothalamic projections on the synchrony in a thalamic network, and uncover the underlying control mechanism, leading to a control method which is applicable for several types of oscillations in the central nervous system.
Mayer
Jörg
J
Institute for Theoretical Physics and Astrophysics, University of Kiel, 24098 Kiel, Germany.
Schuster
Heinz Georg
HG
Claussen
Jens Christian
JC
Mölle
Matthias
M
D002540:Cerebral Cortex / Q000502:physiology*; D003344:Cortical Synchronization; D004569:Electroencephalography; D006801:Humans; D008959:Models, Neurological; D008962:Models, Theoretical; D009415:Nerve Net / Q000502:physiology*; D009434:Neural Pathways; D009474:Neurons; D012890:Sleep; D009435:Synaptic Transmission; D013788:Thalamus / Q000502:physiology*