title: The spectrum of Trp- mutants isolated as 5-fluoroanthranilate-resistant clones in Saccharomyces bayanus, S. mikatae and S. paradoxus.
abstract: 5-Fluoroanthranilic acid (FAA)-resistant mutants were selected in homothallic diploids of three Saccharomyces species, taking care to isolate mutants of independent origin. Mutations were assigned to complementation groups by interspecific complementation with S. cerevisiae tester strains. In all three species, trp3, trp4 and trp5 mutants were recovered. trp1 mutants were also recovered if the selection was imposed on a haploid strain. Thus, FAA selection may be more generally applicable than was previously described.
authors.affiliation: Department of Biological Sciences, Carnegie Mellon University, Pittsburgh, PA 15213, USA. ej09@andrew.cmu.edu
authors.forename: Elizabeth W
authors.initials: EW
authors.lastname: Jones
authors.forename: Peter B
authors.initials: PB
authors.lastname: Berget
authors.forename: James M
authors.initials: JM
authors.lastname: Burnette
authors.forename: Candice
authors.initials: C
authors.lastname: Anderson
authors.forename: Denise
authors.initials: D
authors.lastname: Asafu-Adjei
authors.forename: Seda
authors.initials: S
authors.lastname: Avetisian
authors.forename: Fatmata
authors.initials: F
authors.lastname: Barrie
authors.forename: Ruby
authors.initials: R
authors.lastname: Chen
authors.forename: Bur
authors.initials: B
authors.lastname: Chu
authors.forename: Samantha
authors.initials: S
authors.lastname: Conroy
authors.forename: Sean
authors.initials: S
authors.lastname: Conroy
authors.forename: Allyson
authors.initials: A
authors.lastname: Dill
authors.forename: Will
authors.initials: W
authors.lastname: Eimer
authors.forename: Diane
authors.initials: D
authors.lastname: Garrity
authors.forename: Alexander
authors.initials: A
authors.lastname: Greenwood
authors.forename: Tamara
authors.initials: T
authors.lastname: Hamilton
authors.forename: Simon
authors.initials: S
authors.lastname: Hucko
authors.forename: Carmen
authors.initials: C
authors.lastname: Jackson
authors.forename: Kristen
authors.initials: K
authors.lastname: Livesey
authors.forename: Tiffany
authors.initials: T
authors.lastname: Monaco
authors.forename: Christina
authors.initials: C
authors.lastname: Onorato
authors.forename: Mai
authors.initials: M
authors.lastname: Otsuka
authors.forename: Satyan
authors.initials: S
authors.lastname: Pai
authors.forename: George
authors.initials: G
authors.lastname: Schaeffer
authors.forename: Sharon
authors.initials: S
authors.lastname: Shung
authors.forename: Samantha
authors.initials: S
authors.lastname: Spath
authors.forename: Jonathan
authors.initials: J
authors.lastname: Stahlman
authors.forename: Blake
authors.initials: B
authors.lastname: Sweeney
authors.forename: Elizabeth
authors.initials: E
authors.lastname: Wiltrout
authors.forename: Daniel
authors.initials: D
authors.lastname: Yurovsky
authors.forename: Andrea
authors.initials: A
authors.lastname: Zonneveld
mesh_terms: D019747:Aldose-Ketose Isomerases / Q000235:genetics / Q000378:metabolism; D000878:Anthranilate Synthase / Q000235:genetics / Q000378:metabolism; D005656:Fungal Proteins / Q000235:genetics; D005816:Genetic Complementation Test; D007209:Indole-3-Glycerol-Phosphate Synthase / Q000235:genetics / Q000378:metabolism; D009154:Mutation; D012440:Saccharomyces / Q000187:drug effects / Q000235:genetics* / Q000302:isolation & purification / Q000378:metabolism; D014364:Tryptophan / Q000235:genetics* / Q000378:metabolism; D062367:ortho-Aminobenzoates / Q000378:metabolism / Q000494:pharmacology*
chemical_list: D005656:Fungal Proteins; D062367:ortho-Aminobenzoates; D014364:Tryptophan; D007209:Indole-3-Glycerol-Phosphate Synthase; D000878:Anthranilate Synthase; D019747:Aldose-Ketose Isomerases