Absolute configuration of 8-Amino-3,8-dideoxyoct-2-ulosonic acid, the chemical hallmark of lipopolysaccharides of the genus Shewanella.
The novel monosaccharide 8-amino-3,8-dideoxyoct-2-ulosonic acid (Kdo8N) was isolated by methanolysis from the lipooligosaccharide of the marine Gram-negative bacterium Shewanella pacifica. After HPLC purification, the absolute configuration was determined by the Mosher ester method and proven to be 4 R,5 R,6 R,7 R. This established the d- manno- configuration of the monosaccharide.
Leone
Serena
S
Dipartimento di Chimica Organica e Biochimica, Università degli Studi di Napoli Federico II, Via Cintia 4, I-80126 Napoli, Italy.
Molinaro
Antonio
A
De Castro
Cristina
C
Baier
Andreas
A
Nazarenko
Evgeny L
EL
Lanzetta
Rosa
R
Parrilli
Michelangelo
M
D008070:Lipopolysaccharides / Q000737:chemistry*; D015394:Molecular Structure; D011135:Polysaccharides, Bacterial / Q000737:chemistry*; D020592:Shewanella / Q000737:chemistry*; D013400:Sugar Acids / Q000737:chemistry*
C524915:8-amino-3,8-dideoxyoct-2-ulosonic acid; D008070:Lipopolysaccharides; D011135:Polysaccharides, Bacterial; D013400:Sugar Acids