title: Betraying the parasite's redox system: diaryl sulfide-based inhibitors of trypanothione reductase: subversive substrates and antitrypanosomal properties.
authors.affiliation: Laboratorium für Organische Chemie, ETH Zürich, Hönggerberg, HCI, 8093 Zürich, Switzerland.
authors.forename: Bernhard
authors.initials: B
authors.lastname: Stump
authors.forename: Marcel
authors.initials: M
authors.lastname: Kaiser
authors.forename: Reto
authors.initials: R
authors.lastname: Brun
authors.forename: R Luise
authors.initials: RL
authors.lastname: Krauth-Siegel
authors.forename: François
authors.initials: F
authors.lastname: Diederich
mesh_terms: D000818:Animals; D004791:Enzyme Inhibitors / Q000493:pharmacokinetics / Q000494:pharmacology*; D007891:Leishmania / Q000201:enzymology*; D009247:NADH, NADPH Oxidoreductases / Q000037:antagonists & inhibitors* / Q000378:metabolism; D010084:Oxidation-Reduction; D013379:Substrate Specificity; D013440:Sulfides / Q000493:pharmacokinetics / Q000494:pharmacology*; D014344:Trypanocidal Agents / Q000493:pharmacokinetics / Q000494:pharmacology*; D014345:Trypanosoma / Q000201:enzymology*
chemical_list: D004791:Enzyme Inhibitors; D013440:Sulfides; D014344:Trypanocidal Agents; D009247:NADH, NADPH Oxidoreductases; C049608:trypanothione reductase