[The role of factors determining rheological properties of blood in mechanisms of adaptation and damage in water imbalance].
The study was made of hematological, rheological and biochemical blood parameters of white male rats in daily intramuscular injection of 0.02 mcg of desmopressin and regular periodic hyperhydration of the organism achieved by introduction of 10% water loading within 3, 6, 9 days. The results evidence for significant action of desmopressin on liquid homeostasis not only by antidiuretic effects on the kidneys, by changing the condition of connecting tissue of the matrix as shown by a marked rise of acid GAG in plasm but also by influence on rheological properties of blood which is an important element of management of transcapillary exchange in tissue microregions.
Zdiumaeva
N P
NP
Levin
V N
VN
D000222:Adaptation, Physiological; D000818:Animals; D050034:Antidiuretic Agents / Q000008:administration & dosage; D001809:Blood Viscosity; D003894:Deamino Arginine Vasopressin / Q000008:administration & dosage; D006025:Glycosaminoglycans / Q000097:blood; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D012212:Rheology; D014869:Water Intoxication / Q000097:blood* / Q000139:chemically induced
D050034:Antidiuretic Agents; D006025:Glycosaminoglycans; D003894:Deamino Arginine Vasopressin