First occurrence of an IMP metallo-beta-lactamase in Aeromonas caviae: IMP-19 in an isolate from France.
We describe the first IMP metallo-beta-lactamase in Aeromonas caviae: IMP-19, which differed from IMP-2 by a single amino acid change (Arg to Ala at position 38). bla(IMP-19) was found within a class 1 integron located on a 35-kb plasmid. This is also the first description of an IMP producer in France.
Neuwirth
Catherine
C
Laboratoire de Bactériologie, Hôpital Universitaire du Bocage, BP 77908, 21079 Dijon Cedex, France. catherine.neuwirth@chu-dijon.fr
Siebor
Eliane
E
Robin
Frederic
F
Bonnet
Richard
R
D000333:Aeromonas / Q000187:drug effects / Q000201:enzymology / Q000235:genetics*; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D005602:France; D032023:Integrons / Q000235:genetics*; D007700:Kinetics; D008826:Microbial Sensitivity Tests; D008969:Molecular Sequence Data; D010957:Plasmids / Q000235:genetics*; D017422:Sequence Analysis, DNA; D013379:Substrate Specificity; D001618:beta-Lactamases / Q000235:genetics* / Q000378:metabolism; D047090:beta-Lactams / Q000494:pharmacology
D000900:Anti-Bacterial Agents; D047090:beta-Lactams; C409201:beta-lactamase IMP-1; D001618:beta-Lactamases