title: [Genetic imprinting and embryonic development].
abstract: Erasure, establishment and maintenance of genetic imprinting are indispensable for normal embryonic development. All these processes depend on accurate expression and intimate cooperation of kinds of DNA methyltransferases. Many genetic syndromes and embryo developmental anomalies are caused by abnormality of genetic imprinting. Genetic imprinting is important for the nucleus totipotential of primordial germ cell, maturation of gamete,growth and development of embryo, structure and function of placenta as well as postnatal growth and development of individuals.
authors.affiliation: The Affiliated Obstetrics and Gynecology HospitalìCollege of Medicine, Zhejiang University, Hangzhou, China.
authors.forename: Li-jun
authors.initials: LJ
authors.lastname: Yin
authors.forename: He-feng
authors.initials: HF
authors.lastname: Huang
mesh_terms: D000818:Animals; D019175:DNA Methylation; D015254:DNA Modification Methylases / Q000235:genetics / Q000378:metabolism; D047108:Embryonic Development / Q000235:genetics*; D018392:Genomic Imprinting / Q000235:genetics*; D006801:Humans; D009154:Mutation
chemical_list: D015254:DNA Modification Methylases