Fibrinogen Leipzig II (gamma351Gly-->Ser and gamma82Ala-->Gly): hypodysfibrinogenaemia due to two independent amino acid substitutions within the same polypeptide chain.
Meyer
Michael
M
Department of Biomedical Engineering and Biotechnology, University of Applied Sciences (FH), Carl-Zeiss-Promenade 2, 07745 Jena, Germany. michael.meyer@fh-jena.de
Dietzel
Hermann
H
Kaetzel
Ralph
R
Schmidt
David
D
Liebscher
Karin
K
Brennan
Stephen O
SO
D000328:Adult; D000347:Afibrinogenemia / Q000235:genetics*; D000409:Alanine / Q000235:genetics; D005340:Fibrinogen / Q000235:genetics* / Q000378:metabolism; D005998:Glycine / Q000235:genetics; D006239:Haplotypes; D006470:Hemorrhage; D006579:Heterozygote; D006801:Humans; D008297:Male; D008957:Models, Genetic; D009154:Mutation; D012694:Serine / Q000235:genetics; D021241:Spectrometry, Mass, Electrospray Ionization; D013997:Time Factors
D012694:Serine; D005340:Fibrinogen; D000409:Alanine; D005998:Glycine