title: Submandibular area metastasis from prostate small cell carcinoma with neuroendocrine differentiation.
abstract: Neuroendocrine differentiation in prostatic carcinomas generally confers a more aggressive clinical behavior and less favorable prognosis than usual prostatic carcinomas. In this article, we report a case of a 65-year-old man with prostatic carcinoma who had a metastasis of the submandibular area. His serum prostate-specific antigen level was reduced to below the normal range and carcinoembryonic antigen was increased. Pathologic specimens demonstrated a small cell carcinoma with neuroendocrine differentiation by immunohistochemical studies.
authors.affiliation: Department of Oral and Maxillofacial Surgery, The Medical School Hospital of Qingdao University, Qingdao, the People's Republic of China.
authors.forename: Wen-lin
authors.initials: WL
authors.lastname: Xiao
authors.forename: Fu-ting
authors.initials: FT
authors.lastname: Zhou
authors.forename: Yuan-yong
authors.initials: YY
authors.lastname: Feng
authors.forename: Ning-yi
authors.initials: NY
authors.lastname: Li
mesh_terms: D000368:Aged; D018288:Carcinoma, Small Cell / Q000556:secondary*; D006801:Humans; D008297:Male; D011471:Prostatic Neoplasms / Q000473:pathology*; D013365:Submandibular Gland Neoplasms / Q000556:secondary*