A temporal frequency-dependent functional architecture in human V1 revealed by high-resolution fMRI.
Although cortical neurons with similar functional properties often cluster together in a columnar organization, only ocular dominance columns, the columnar structure representing segregated anatomical input (from one of the two eyes), have been found in human primary visual cortex (V1). It has yet to be shown whether other columnar organizations that arise only from differential responses to stimulus properties also exist in human V1. Using high-resolution functional magnetic resonance imaging, we have found such a functional architecture containing domains that respond preferentially to either low or high temporal frequency.
Sun
Pei
P
Laboratory for Cognitive Brain Mapping, RIKEN Brain Science Institute, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan. psun@brain.riken.jp
Ueno
Kenichi
K
Waggoner
R Allen
RA
Gardner
Justin L
JL
Tanaka
Keiji
K
Cheng
Kang
K
D001931:Brain Mapping; D007839:Functional Laterality / Q000502:physiology*; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008279:Magnetic Resonance Imaging; D009949:Orientation / Q000502:physiology*; D010100:Oxygen / Q000097:blood; D010775:Photic Stimulation; D014793:Visual Cortex / Q000098:blood supply* / Q000502:physiology; D014795:Visual Pathways / Q000098:blood supply* / Q000502:physiology
D010100:Oxygen