title: Head and neck cancer: the possible role of stem cells.
abstract: There is a rising interest in the field of oncology in order to understand if cancer stem cells can play a key role also in the pathogenesis of head and neck tumors. It is likely that cancer stem cells are a minor population of tumor cells that possess the stem cell property of self-renewal. In addition, dysregulation of stem cell self-renewal is a likely requirement for the development of cancer. This new model for cancer will have significant ramifications for the way we will study and treat tumors. The authors are proposing a discussion of this topic, which, in their opinion, need to be further investigated in the ENT field.
authors.affiliation: ENT Department, University Hospital of Ferrara, C.so Giovecca 203, 44100, Ferrara, Italy. chiara.bianchini@unife.it
authors.forename: C
authors.initials: C
authors.lastname: Bianchini
authors.forename: A
authors.initials: A
authors.lastname: Ciorba
authors.forename: S
authors.initials: S
authors.lastname: Pelucchi
authors.forename: R
authors.initials: R
authors.lastname: Piva
authors.forename: A
authors.initials: A
authors.lastname: Pastore
mesh_terms: D006258:Head and Neck Neoplasms / Q000503:physiopathology*; D006801:Humans; D014411:Neoplastic Stem Cells / Q000502:physiology*