title: Seasonality bias in adverse pregnancy outcomes in Siberia.
abstract: OBJECTIVE
  To examine which months are unfavourable for conception in the region with the severe continental climate.
  
  
  METHODS
  Retrospective population based study.
  
  
  METHODS
  Monthly data on incidence rate for gestose, maternal anaemia, pyelonephritis, threat to spontaneous abortion, stillbirth, perinatal death and infant death at age under one year were extracted from medical records of obstetric, delivery, and paediatric hospitals in Novosibirsk (1976-1980), Norilsk (Taimir peninsula), and Mirny (western Yakutia). Two latter towns were considered together as a northern setting. Edwards' method was applied to test seasonality.
  
  
  RESULTS
  In Novosibirsk as well as in northern towns, the monthly distribution of time of conception for preterm births, maternal pyelonephritis, and infant deaths displays significant seasonal pattern with maximum in summer. Additionally in the North, stillbirths' conceptions also tended to be concentrated in June.
  
  
  CONCLUSIONS
  In Siberia, the polar day and summer months are an unfavourable time for conceiving in respect to obstetric complications and adverse pregnancy outcomes.
authors.affiliation: Institute of Physiology, SB RAMS, Novosibirsk, Russia.
authors.forename: Vladimir N
authors.initials: VN
authors.lastname: Melnikov
authors.forename: Galina A
authors.initials: GA
authors.lastname: Skosyreva
authors.forename: Sergey G
authors.initials: SG
authors.lastname: Krivoschekov
mesh_terms: D002940:Circadian Rhythm; D002980:Climate; D005260:Female; D005843:Geography; D006801:Humans; D015994:Incidence; D009774:Obstetrics; D011247:Pregnancy; D011248:Pregnancy Complications / Q000453:epidemiology*; D011256:Pregnancy Outcome; D012189:Retrospective Studies; D012307:Risk Factors; D012621:Seasons; D012800:Siberia / Q000453:epidemiology; D050497:Stillbirth; D013997:Time Factors