title: Homotopic dynamics of telomeric loops in mammalian chromatids.
abstract: Asymmetric transfer of a solitonic kink between telomeric loops shared by template-replica chromatids is conceptualized in terms of homotopic dynamics. Downscaled to B-Z DNA these ideas lead to interesting possibilities regarding duplication and/or selective activation of genes located at or near DNA "hybrid" chiralities.
authors.affiliation: Department of Neurological Surgery, USC Keck School of Medicine, 2025 Zonal Avenue, RMR 424, Los Angeles, CA 90033, USA. mnjabbou@usc.edu
authors.forename: M N
authors.initials: MN
authors.lastname: Jabbour
authors.forename: G T
authors.initials: GT
authors.lastname: Matioli
mesh_terms: D000705:Anaphase / Q000235:genetics; D000818:Animals; D002842:Chromatids / Q000235:genetics*; D004247:DNA / Q000235:genetics; D008322:Mammals / Q000235:genetics; D008957:Models, Genetic; D016615:Telomere / Q000235:genetics*
chemical_list: D004247:DNA