One-pot terminal alkene homologation using a tandem olefin cross-metathesis/allylic carbonate reduction sequence.
A one-carbon homologation of terminal alkenes has been developed utilizing an olefin cross-metathesis followed by a palladium-mediated allylic carbonate reduction; various substrates were used to demonstrate the scope of the reaction, with yields ranging from 65 to 86%.
Comins
Daniel L
DL
Department of Chemistry, North Carolina State University, Raleigh, NC, USA. Daniel_Comins@ncsu.edu
Dinsmore
Jason M
JM
Marks
Lucas R
LR
D000475:Alkenes / Q000737:chemistry*; D002254:Carbonates / Q000737:chemistry*; D003432:Cross-Linking Reagents / Q000737:chemistry*; D046529:Microscopy, Electron, Transmission; D015394:Molecular Structure; D010084:Oxidation-Reduction; D013057:Spectrum Analysis; D017186:Titrimetry
D000475:Alkenes; D002254:Carbonates; D003432:Cross-Linking Reagents