title: [A case of long-term survival of advanced penile carcinoma treated with combination therapy].
abstract: A 72-year-old man with genital ulcerative tumor was introduced to our hospital in December 1997. The pathological examination revealed well differentiated squamous cell carcinoma. A diagnosis by computed tomography and magnetic resonance imaging indicated that a locally advanced penile carcinoma had infiltrated the urethra, prostate, pubic bone and there was also bilateral inguinal lymphoadenopathy. Linac irradiation (40Gy/4 weeks) combined with once-a-week administration of THP-ADM were indicated. One month after the combination therapy, the tumor size had become small enough to allow curative surgical treatment. Pathological examination revealed no positive margin. For eight years since this radical treatment, the patient has been healthy with no local recurrence and no distant metastatic lesion.
authors.affiliation: Department of Urology, Fukushima Medical University School of Medicine, Fukushima, Japan.
authors.forename: Michiko
authors.initials: M
authors.lastname: Nakano
authors.forename: Mitsuharu
authors.initials: M
authors.lastname: Iwasaki
authors.forename: Yasukuni
authors.initials: Y
authors.lastname: Yoshimura
authors.forename: Osamu
authors.initials: O
authors.lastname: Yamaguchi
authors.forename: Hisashi
authors.initials: H
authors.lastname: Uchida
authors.forename: Tatsuru
authors.initials: T
authors.lastname: Hashimoto
mesh_terms: D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001761:Bleomycin / Q000008:administration & dosage; D002294:Carcinoma, Squamous Cell / Q000188:drug therapy / Q000532:radiotherapy / Q000601:surgery / Q000628:therapy*; D003131:Combined Modality Therapy; D004317:Doxorubicin / Q000008:administration & dosage / Q000031:analogs & derivatives; D004334:Drug Administration Schedule; D006801:Humans; D008197:Lymph Node Excision; D008297:Male; D010412:Penile Neoplasms / Q000188:drug therapy / Q000532:radiotherapy / Q000601:surgery / Q000628:therapy*; D017741:Survivors
chemical_list: D001761:Bleomycin; D004317:Doxorubicin; C027260:pirarubicin