title: Severe pulmonary hypertension due to chronic echinococcal pulmonary emboli treated with targeted pulmonary vascular therapy and hepatic resection.
abstract: Hydatid disease (human echinococcosis) is a zoonotic infection caused by larval forms (metacestodes) of the genus Echinococcus. Although pulmonary hypertension (PH) due to hydatid disease has been described, it is quite rare. We report a patient with chronic echinococcal embolic PH in whom treatment with novel PH therapies permitted successful resection of the hepatic cyst with a good outcome.
authors.affiliation: Department of Medicine, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA.
authors.forename: William
authors.initials: W
authors.lastname: Bulman
authors.forename: Christina M
authors.initials: CM
authors.lastname: Coyle
authors.forename: Tricia E
authors.initials: TE
authors.lastname: Brentjens
authors.forename: Evelyn M
authors.initials: EM
authors.lastname: Horn
authors.forename: Marc L
authors.initials: ML
authors.lastname: Dickstein
authors.forename: Jessie S
authors.initials: JS
authors.lastname: Wilt
authors.forename: Jean
authors.initials: J
authors.lastname: Emond
authors.forename: Steven M
authors.initials: SM
authors.lastname: Kawut
mesh_terms: D000328:Adult; D000959:Antihypertensive Agents / Q000627:therapeutic use; D000077300:Bosentan; D002908:Chronic Disease; D004444:Echinococcosis, Hepatic / Q000150:complications / Q000601:surgery; D004445:Echinococcosis, Pulmonary / Q000150:complications*; D011464:Epoprostenol / Q000627:therapeutic use; D006498:Hepatectomy; D006801:Humans; D006976:Hypertension, Pulmonary / Q000188:drug therapy* / Q000209:etiology*; D008297:Male; D011651:Pulmonary Artery / Q000469:parasitology / Q000473:pathology; D011655:Pulmonary Embolism / Q000150:complications*; D013449:Sulfonamides / Q000627:therapeutic use; D020775:Thoracic Surgery, Video-Assisted; D014682:Vena Cava, Inferior / Q000601:surgery
chemical_list: D000959:Antihypertensive Agents; D013449:Sulfonamides; D011464:Epoprostenol; D000077300:Bosentan