title: [Evaluation of 126 radical cystectomy with orthotopic ileal or sigmoidocolic neobladder].
abstract: OBJECTIVE
  To evaluate the long-term clinical effects of orthotopic ileal or sigmoidocolic neobladder.
  
  
  METHODS
  One hundred and twenty six patients with bladder cancer who underwent radical cystectomy and orthotopic ileal or sigmoidocolic neobladder from 1989 to 2001 were followed up, the clinical data was collected and analysed. Hautmann orthotopic ileal neobladder was performed on 84 cases and orthotopic sigmoidocolic neobladder was performed on 42 cases; Lymph node clearing during surgery was performed on 62 cases, chemotherapy and radiotherapy was performed on 64 cases after surgery. The continence and complications were compared between sigmoidocolic group and ileal group, the tumor recurrent rate and the 5-year survival rate were compared between lymphnode clearing group and chemoradical therapy group.
  
  
  RESULTS
  Complete follow up was performed in 122 cases. Ureter broaden and urine backflow rate were higher in sigmoidocolic group than in ileal group (P < 0.05), nocturnal continence rate in sigmoidocolic group was higher than in ileal group (P < 0.05); Post-surgical tumor recurrent rate in lymphnode clearing group was lower than in chemoradical therapy group (P < 0.05), the 5-year survival rate in lymphnode clearing group was higher than in chemoradical therapy group (P < 0.05). The overall short-term complication rate was 15.9% (20/126), the overall long-term complication rate was 9.8% (12/122).
  
  
  CONCLUSIONS
  The effects of orthotopic ileal or sigmoidocolic neobladder were satisfactory with low complication rate, lymphnode clearing during the surgery can increase the 5-year survival rate when compared with the chemoradical group.
authors.affiliation: Department of Urology, Second Xiang-Ya Hospital of Central South University, Changsha 410011, China.
authors.forename: Long-kai
authors.initials: LK
authors.lastname: Peng
authors.forename: Shao-jie
authors.initials: SJ
authors.lastname: Yu
authors.forename: Luo-yan
authors.initials: LY
authors.lastname: Yang
authors.forename: Xu-biao
authors.initials: XB
authors.lastname: Xie
authors.forename: Feng-hua
authors.initials: FH
authors.lastname: Peng
authors.forename: Jin-rui
authors.initials: JR
authors.lastname: Yang
authors.forename: Xiao-kun
authors.initials: XK
authors.lastname: Zhao
authors.forename: Shan-qun
authors.initials: SQ
authors.lastname: Chen
authors.forename: Xian-ling
authors.initials: XL
authors.lastname: Liu
mesh_terms: D000328:Adult; D000368:Aged; D015653:Cystectomy / Q000379:methods*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007082:Ileum / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D001749:Urinary Bladder Neoplasms / Q000601:surgery*; D014547:Urinary Diversion / Q000379:methods*; D016476:Urinary Reservoirs, Continent