title: [A case of Sweet's syndrome with a variety of chest radiological findings].
abstract: We report a rare case of Sweet's syndrome (acute febrile neutrophilic dermatosis) with a variety of chest radiological findings. A 73-year-old man, who had been treated with corticosteroid for Sweet's syndrome for 2 years, was admitted to our hospital because of pyrexia with a infiltrative chest shadow. Chest CT scans showed consolidation and ground-glass opacities with air-bronchogram in the right lower lobe. Treatment with antibiotics seemed to be effective but there was no improvement of chest shadows. Simultaneously with his pyrexia, diffuse centrilobular-micronodular shadows and a mass-like shadow appeared on chest CT after 2 months and after the next 2 months, respectively. Bronchoalveolar lavage fluid contained increased neutrophils but not any infectious pathogen. Transbronchial lung biopsy specimens revealed chronic interstitial infiltrate with alveolar wall thickening and neutrophil accumulation in the airspace. A diagnosis of pulmonary involvement in a patient with Sweet's syndrome was finally made and he was successfully treated with corticosteroid.
authors.affiliation: Department of Internal Medicine, Oita Prefectural Hospital.
authors.forename: Hisako
authors.initials: H
authors.lastname: Kushima
authors.forename: Shunji
authors.initials: S
authors.lastname: Mizunoe
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Ishii
authors.forename: Kazuhiko
authors.initials: K
authors.lastname: Hashinaga
authors.forename: Toru
authors.initials: T
authors.lastname: Yamasaki
authors.forename: Kenji
authors.initials: K
authors.lastname: Kishi
authors.forename: Issei
authors.initials: I
authors.lastname: Tokimatsu
authors.forename: Kazufumi
authors.initials: K
authors.lastname: Hiramatsu
authors.forename: Jun-ichi
authors.initials: J
authors.lastname: Kadota
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000368:Aged; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage; D006801:Humans; D008168:Lung / Q000000981:diagnostic imaging*; D008297:Male; D011239:Prednisolone / Q000008:administration & dosage; D016463:Sweet Syndrome / Q000150:complications* / Q000188:drug therapy; D014057:Tomography, X-Ray Computed
chemical_list: D000305:Adrenal Cortex Hormones; D000893:Anti-Inflammatory Agents; D011239:Prednisolone