Smaller building blocks form larger assemblies: aggregation behavior of biaryl-based dendritic facial amphiphiles.
Synthesis and micellar behavior of biaryl-based benzyl ether dendritic molecules prepared from a new biaryl building block are described. The key objective of the study is to tune the size of individual dendritic molecules and investigate its effect on aggregation behavior of the resulting micelle-like assemblies. We show that the functional group placement in the building block influences flexibility of the dendritic backbone and interior volume available for packing the hydrophobic groups, which is reflected in different aggregation behavior and aggregate size of the two types of micellar assemblies.
Ambade
Ashootosh V
AV
Department of Chemistry, University of Massachusetts, Amherst, Massachusetts 01003, USA.
Aathimanikandan
Sivakumar V
SV
van der Poll
Derek
D
Thayumanavan
S
S
D001593:Benzyl Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D001713:Biphenyl Compounds / Q000737:chemistry*; D050091:Dendrimers / Q000138:chemical synthesis* / Q000737:chemistry; D004987:Ethers / Q000138:chemical synthesis* / Q000737:chemistry; D008823:Micelles; D008958:Models, Molecular; D015394:Molecular Structure; D013237:Stereoisomerism; D013499:Surface Properties; D013501:Surface-Active Agents / Q000737:chemistry*
D001593:Benzyl Compounds; D001713:Biphenyl Compounds; D050091:Dendrimers; D004987:Ethers; D008823:Micelles; D013501:Surface-Active Agents