title: Topical iodophor use in chronic wounds: a literature review.
abstract: This study aimed to do a review of the literature regarding the use of topic iodine and/or compounds in the treatment of chronic wounds. The clinical trials were searched in the Cochrane database. Fourteen (58.3%) among 24 studies fulfilled the inclusion criteria. The articles were analyzed regarding journal and study characteristics and classified into three groups: Iodine versus other topic agents (7/ 50%); Iodine versus different dressings (6/ 42.9%); Iodine versus without Iodine (1/ 7.1%). Favorable results for the use of Iodine or similar product occurred in 50% of the analyzed studies. Six out of 8 trials showed favorable results for healing and infection prevention/ treatment; 4 out of 5 were not favorable when the healing objective was investigated and 1 study for infection treatment showed no favorable result.
authors.affiliation: Hospital Beneficência Portuguesa de São Paulo, Brazil.
authors.forename: Alcicléa dos Santos
authors.initials: Ados S
authors.lastname: Oliveira
authors.forename: Vera Lúcia Conceição de Gouveia
authors.initials: VL
authors.lastname: Santos
mesh_terms: D000287:Administration, Topical; D000891:Anti-Infective Agents, Local / Q000008:administration & dosage*; D002908:Chronic Disease; D002986:Clinical Trials as Topic; D006801:Humans; D007231:Infant, Newborn; D007455:Iodine / Q000008:administration & dosage*; D014945:Wound Healing; D014946:Wound Infection / Q000517:prevention & control; D014947:Wounds and Injuries / Q000188:drug therapy*
chemical_list: D000891:Anti-Infective Agents, Local; D007455:Iodine