Recognition of imidazoles by strapped zinc(II) porphyrin receptors: insight into the induced-fit mechanism.
Imidazole-porphyrin coordination has become an important tool in the design of self-assembled materials. A combination of spectrophotometric and stopped-flow techniques has been used to gain insight into the control of imidazole binding in the distal pocket of phenanthroline-strapped porphyrins. The binding studies of a variety of imidazole substrates in combination with both hindered and accessible receptors have permitted the determination of the thermodynamic and kinetic parameters associated with the imidazole binding.
Brandel
Jeremy
J
Laboratoire de Physico-Chimie Bioinorganique, ULP-CNRS (UMR 7177), Institut de Chimie, ECPM, 25 rue Becquerel, 67200 Strasbourg, France.
Trabolsi
Ali
A
Melin
Frédéric
F
Elhabiri
Mourad
M
Weiss
Jean
J
Albrecht-Gary
Anne-Marie
AM
D007093:Imidazoles / Q000737:chemistry*; D008665:Metalloporphyrins / Q000737:chemistry*; D011956:Receptors, Cell Surface / Q000737:chemistry*
D007093:Imidazoles; D008665:Metalloporphyrins; D011956:Receptors, Cell Surface; C017802:zinc hematoporphyrin