Variation in the FTO gene locus is associated with cerebrocortical insulin resistance in humans.
Tschritter
O
O
Preissl
H
H
Yokoyama
Y
Y
Machicao
F
F
Häring
H-U
HU
Fritsche
A
A
D000071516:Alpha-Ketoglutarate-Dependent Dioxygenase FTO; D015992:Body Mass Index; D002540:Cerebral Cortex / Q000378:metabolism* / Q000473:pathology; D005260:Female; D020022:Genetic Predisposition to Disease; D005838:Genotype; D006801:Humans; D007328:Insulin / Q000378:metabolism / Q000494:pharmacology; D007333:Insulin Resistance / Q000235:genetics*; D050417:Insulin-Secreting Cells / Q000187:drug effects / Q000378:metabolism; D015810:Linkage Disequilibrium; D008297:Male; D009765:Obesity / Q000235:genetics / Q000378:metabolism; D050177:Overweight / Q000235:genetics / Q000378:metabolism; D011110:Polymorphism, Genetic; D011506:Proteins / Q000235:genetics*
D007328:Insulin; D011506:Proteins; D000071516:Alpha-Ketoglutarate-Dependent Dioxygenase FTO; C526492:FTO protein, human