title: Spontaneous regression of lipomyelomeningocele associated with terminal syringomyelia in a child. Case report.
abstract: The authors present the case of a 3-month-old girl who presented with lipomyelomeningocele (LMM) associated with a low-lying conus and a terminal syrinx. At the time of presentation, the girl had a mild neurological, but congenital, deficit: weakness of the right foot and calf as well as absence of the right ankle reflex. Bladder assessment was normal, and it was decided to monitor this child closely, without performing surgery. Results of further magnetic resonance imaging performed 1 year after diagnosis and when the girl was 28 months old, showed a significant regression of LMM and associated syrinx. Interestingly, the child remained neurologically unchanged. Although described in the literature, spontaneous regression of LMM is a very unusual situation, and very few cases have been reported. This case represents the first report of concomitant regression of an associated syrinx. Close follow-up of nonsurgically treated children is mandatory, as the risk of late deterioration remains.
authors.affiliation: Department of Neurosurgery, Great Ormond Street Hospital for Children, London, United Kingdom.
authors.forename: Olivier
authors.initials: O
authors.lastname: Klein
authors.forename: Dominic
authors.initials: D
authors.lastname: Thompson
mesh_terms: D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008067:Lipoma / Q000473:pathology*; D008279:Magnetic Resonance Imaging; D008591:Meningomyelocele / Q000473:pathology*; D012075:Remission, Spontaneous; D016135:Spinal Dysraphism / Q000473:pathology*; D013595:Syringomyelia / Q000473:pathology*