title: [Examination of tumor diameter measurement precision by RECIST].
abstract: Image evaluation with Response Evaluation Criteria in Solid Tumors (RECIST) evaluates the change in a measurable lesion as determined by ruler or micrometer caliper. However, there is no definition of the conditions thought to influence the precision of measurement. We therefore examined the effects on measurement precision by changing image amplification, WW, WL, and time phase. Moreover, to determine response rate, one-dimensional evaluation with RECIST was compared with the two-dimensional evaluation of World Health Organization (WHO) for a hepatocellular carcinoma. The results of measuring the object lesion for measured value variation were as follows. Under image conditions of 1 time expansion/ WW 150/ WL 100 was (4.92+/-1.94)%. Under image conditions of 1 time expansion/ WW 350/ WL 75 was (4.42+/-1.70)%. Under image conditions of 4 times expansion/ WW 150/ WL 100 was (2.52+/-0.82)%. Under image conditions of 4 times expansion/ WW 350/ WL 75 was (2.83+/-1.10)%. When an image was enlarged to 4 times, precision doubled. There was no a difference in comparing RECIST to WHO in terms of response rate. Thus the best method was considered to be RECIST because of its convenience.
authors.affiliation: Department of Radiological Technology, University of Tokyo Hospital.
authors.forename: Masami
authors.initials: M
authors.lastname: Goto
authors.forename: Kenji
authors.initials: K
authors.lastname: Ino
authors.forename: Masaaki
authors.initials: M
authors.lastname: Akahane
authors.forename: Miwa
authors.initials: M
authors.lastname: Yamashita
authors.forename: Yuuichi
authors.initials: Y
authors.lastname: Suzuki
authors.forename: Toshikazu
authors.initials: T
authors.lastname: Imae
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Hasegawa
authors.forename: Katsuji
authors.initials: K
authors.lastname: Nishida
authors.forename: Keiichi
authors.initials: K
authors.lastname: Yano
authors.forename: Kyouhito
authors.initials: K
authors.lastname: Iida
authors.forename: Kazuo
authors.initials: K
authors.lastname: Mima
authors.forename: Kuni
authors.initials: K
authors.lastname: Ohtomo
mesh_terms: D006528:Carcinoma, Hepatocellular / Q000000981:diagnostic imaging / Q000473:pathology; D006801:Humans; D008113:Liver Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology; D009369:Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D011859:Radiography; D013679:Technology, Radiologic / Q000379:methods