title: Screening and therapy of pulmonary hypertension in systemic sclerosis.
abstract: OBJECTIVE
  Systemic sclerosis is a major risk factor for the development of pulmonary arterial hypertension. Often this disease is far advanced by the time it is detected in the individual patient, severely impacting quality of life and survival.
  
  
  RESULTS
  Therapeutic options available for patients with scleroderma-associated pulmonary arterial hypertension have increased significantly over the last few years, fueling our desire to improve early detection of disease.
  
  
  CONCLUSIONS
  During the course of this manuscript I will review the literature examining approaches towards screening for scleroderma-associated pulmonary arterial hypertension. I will then discuss the most recent studies examining therapeutic options for patients with this disease.
authors.affiliation: Pulmonary Hypertension Center, Division of Pulmonary Sciences and Critical Care Medicine, University of Colorado Denver Health Sciences Center, Denver, Colorado 80262, USA. todd.bull@uchsc.edu
authors.forename: Todd M
authors.initials: TM
authors.lastname: Bull
mesh_terms: D006801:Humans; D006976:Hypertension, Pulmonary / Q000175:diagnosis* / Q000209:etiology* / Q000628:therapy*; D008403:Mass Screening; D012129:Respiratory Function Tests; D012595:Scleroderma, Systemic / Q000150:complications*