title: ROC volumes--should they be used?
abstract: Invited comment on Alonzo, T.A. and Nakas, C.T. (2007). Comparison of ROC umbrella volumes with an application to the assessment of lung cancer diagnostic markers. Biometrical Journal 49, 654-664. Issues remain as to the appropriateness of volumes as summary measures of accuracy when distinguishing between multiple disease classes and when comparing accuracy of tests.
authors.affiliation: Department of Biostatistics, Virginia Commonwealth University, 730 E. Broad St, Richmond, VA 23298-0032, USA. mcclish@vcu.edu
authors.forename: Donna K
authors.initials: DK
authors.lastname: McClish
mesh_terms: D014408:Biomarkers, Tumor / Q000032:analysis*; D001699:Biometry / Q000379:methods*; D019175:DNA Methylation; D003936:Diagnosis, Computer-Assisted / Q000379:methods*; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis* / Q000453:epidemiology* / Q000235:genetics; D012372:ROC Curve; D012680:Sensitivity and Specificity
chemical_list: D014408:Biomarkers, Tumor