title: Developmental abnormalities of the optic nerve and chiasm.
abstract: Developmental anomalies of the optic nerve are an important and growing cause of lifelong visual handicap and they are often associated with systemic abnormalities. This review focuses on the ocular and systemic aspects of developmental anomalies arising from defects of fetal fissure closure and retinal ganglion cell development, and covers some other optic-disc anomalies that have systemic significance.
authors.affiliation: Institute of Child Health, Visual Sciences Unit, London, UK. d.taylor@ich.ucl.ac.uk
authors.forename: D
authors.initials: D
authors.lastname: Taylor
mesh_terms: D000015:Abnormalities, Multiple; D002869:Chromosome Aberrations; D003103:Coloboma / Q000196:embryology / Q000235:genetics; D006801:Humans; D009897:Optic Chiasm / Q000002:abnormalities / Q000196:embryology; D009900:Optic Nerve / Q000002:abnormalities* / Q000196:embryology; D011296:Prenatal Diagnosis / Q000379:methods; D012165:Retinal Ganglion Cells / Q000473:pathology; D013577:Syndrome