Sequence analysis of the novel HLA-B35 (B*3576) allele in an African individual.
A novel human leucocyte antigen (HLA)-B35 (HLA-B*3576) allele has been described in an African individual by polymerase chain reaction sequence-based typing. This new allele contains six nucleotide substitutions and is homologous to B*3501 with the exception of residues 66-74 resulting in five amino acid mutations.
Aubert
V
V
Division of Immunology and Allergy, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland. vincent.aubert@chuv.ch
Mayerat
C
C
Lopez
N
N
Pantaleo
G
G
D000483:Alleles; D019943:Amino Acid Substitution; D001483:Base Sequence; D044383:Black People; D005260:Female; D015235:HLA-B Antigens / Q000235:genetics; D015797:HLA-B35 Antigen / Q000235:genetics*; D006801:Humans; D008297:Male; D008969:Molecular Sequence Data; D020125:Mutation, Missense; D016133:Polymerase Chain Reaction; D017422:Sequence Analysis, DNA; D017386:Sequence Homology, Amino Acid
D015235:HLA-B Antigens; C500431:HLA-B*35:01 antigen; D015797:HLA-B35 Antigen