title: Suppressive therapy after surgical treatment of thyroid gland cancer in patients with mastopathy.
abstract: State of lactation system during oncological disorders of thyroid gland is one of the poorly studied topics of modern medicine. Controversy in clinical and experimental data creates the need of performing studies in this direction. The goal of this study is to investigate determining pathogenic mechanisms of thyroid and lactation systems. Realization of the study results will enable development of guidelines for prophylaxis, diagnosis and treatment of mammary gland cancer in patients with thyroid gland malignancy. For this purpose we investigated patients with different types of malignant cancer of thyroid gland (after surgery), who had diffuse fibrocystic mastopathy as a concomitant disorder. Patients underwent conservative therapy only with thyroid agents. We observed patients for 6 months since the beginning of the treatment. During this period patients' condition was evaluated several times using examinations involved in the study. Summarization of study results demonstrated that suppressive therapy might prevent precancerous diseases of mammary gland.
authors.affiliation: Georgian-German specialized oncology clinic.
authors.forename: T
authors.initials: T
authors.lastname: Makaridze
authors.forename: K
authors.initials: K
authors.lastname: Mardaleishvili
mesh_terms: D000328:Adult; D001943:Breast Neoplasms / Q000175:diagnosis* / Q000517:prevention & control*; D005260:Female; D005348:Fibrocystic Breast Disease / Q000150:complications / Q000188:drug therapy*; D006801:Humans; D008875:Middle Aged; D013964:Thyroid Neoplasms / Q000150:complications / Q000601:surgery*; D013974:Thyroxine / Q000627:therapeutic use*
chemical_list: D013974:Thyroxine