[Does cerebral salt wasting syndrome exist?].
Increased natriuresis is a frequent situation after subarachnoid haemorrhage (SAH). It may be responsible for hyponatremia, which can be dangerous in case of severe hypo-osmolarity or hypovolemia. Inappropriate secretion of antidiuretic hormone or cerebral salt wasting syndrome (CSWS) have been incriminated for hyponatremia after SAH, but it remains difficult to distinguish between both syndromes. There are many explanations for increased natriuresis after SAH, depending on the level of blood pressure, the volemia, and the presence or not of natriuretic peptides. The cerebral insult and the treatments, which are done to fight against elevated intracranial pressure or vasospasm, can modify any of these parameters. So it appears that the word "cerebral" in CSWS is probably not a good term and it would be better to talk about appropriate or non-appropriate natriuretic response. Corticoïds or urea can be useful for controlling hypernatriuresis.
Leblanc
P-E
PE
Département d'anesthésie-réanimation chirurgicale, faculté de médecine Paris-Sud, Assistance publique-Hôpitaux de Paris, hôpital de Bicêtre, 78, rue du Général-Leclerc, 94275 Le Kremlin-Bicêtre, France. pierre-etienne.leblanc@bct.aphp.fr
Cheisson
G
G
Geeraerts
T
T
Tazarourte
K
K
Duranteau
J
J
Vigué
B
B
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D001794:Blood Pressure; D001927:Brain Diseases / Q000188:drug therapy / Q000453:epidemiology / Q000209:etiology* / Q000503:physiopathology; D003937:Diagnosis, Differential; D006801:Humans; D007010:Hyponatremia / Q000188:drug therapy / Q000453:epidemiology / Q000503:physiopathology*; D020896:Hypovolemia / Q000188:drug therapy / Q000453:epidemiology / Q000503:physiopathology*; D007177:Inappropriate ADH Syndrome / Q000188:drug therapy / Q000453:epidemiology / Q000503:physiopathology; D015994:Incidence; D009318:Natriuresis; D014508:Urea / Q000627:therapeutic use
D000305:Adrenal Cortex Hormones; D014508:Urea