title: [Accelerated phase of idiopathic pulmonary fibrosis].
abstract: The natural history of idiopathic pulmonary fibrosis is characterized by a slow progression resulting in respiratory failure and death. The progression to the fulminant form is rapid in a small percentage of cases, however. Within weeks or months, patients develop respiratory distress, and extensive ground-glass patterns can be seen in computed tomography scans and hyaline membranes in biopsy samples. This is described as an accelerated phase of idiopathic pulmonary fibrosis, in which elevated levels of acute-phase reactants and tumor markers have been reported. To date, the monoclonal tumor marker, CA 15/3 has not been associated with the accelerated phase.
authors.affiliation: Servicio de Neumología, Hospital de Galdakao, Galdakao, Vizcaya, España. lander.altubeurrengoetxea@osakidetza.net
authors.forename: Lander
authors.initials: L
authors.lastname: Altube Urrengoetxea
authors.forename: Carlos
authors.initials: C
authors.lastname: Salinas Solano
authors.forename: Myriam
authors.initials: M
authors.lastname: Aburto Barrenetxea
authors.forename: Francisco Javier
authors.initials: FJ
authors.lastname: Moraza Cortés
authors.forename: Aitor
authors.initials: A
authors.lastname: Ballaz Quincoces
authors.forename: Alberto
authors.initials: A
authors.lastname: Capelastegui Sainz
mesh_terms: D000368:Aged; D018450:Disease Progression; D006801:Humans; D008297:Male; D011658:Pulmonary Fibrosis / Q000175:diagnosis*