title: Iterative approach to polyketide-type structures: stereoselective synthesis of 1,3-polyols utilizing the catalytic asymmetric Overman esterification.
abstract: An iterative systematic approach to the 1,3-polyol motif has been developed to provide access to all possible stereoisomers by utilizing the catalytic asymmetric Overman esterification for the construction of all stereogenic centres.
authors.affiliation: Department Chemie, Technische Universität München, Lichtenbergstr. 4, 85747 Garching, Germany.
authors.forename: Jörg T
authors.initials: JT
authors.lastname: Binder
authors.forename: Stefan F
authors.initials: SF
authors.lastname: Kirsch
mesh_terms: D002384:Catalysis; D004951:Esterification; D018942:Macrolides / Q000737:chemistry*; D015394:Molecular Structure; D011108:Polymers / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D018942:Macrolides; D011108:Polymers; C024617:polyol