title: Ozone therapy in extractive surgery on patients treated with bisphosphonates.
abstract: It is certain that oral extractive surgery is a remarkable trigger to avascular osteonecrosis of the jaw in patients treated with pyrophosphate analogous. This acquisition limits the use of endo-oral surgery in those patients, even when they have already developed the lesions. In this study, we present the results obtained in a group of 15 patients deriving from a 33-patient cluster with osteonecrosis of the jaw in treatment at our department with a new protocol based on ozone therapy. The object of this article is to demonstrate how dental extraction becomes possible in a patient with avascular bisphosphonate-related jaw osteonecrosis or in those who simply received pyrophosphate analogous when proper treatment with ozone therapy has been done.
authors.affiliation: Department of Maxillo-Facial Surgery, University of Rome La Sapienza, Policlinico Umberto I, Rome, Italy.
authors.forename: Alessandro
authors.initials: A
authors.lastname: Agrillo
authors.forename: Pierpaolo
authors.initials: P
authors.lastname: Sassano
authors.forename: Claudio
authors.initials: C
authors.lastname: Rinna
authors.forename: Paolo
authors.initials: P
authors.lastname: Priore
authors.forename: Giorgio
authors.initials: G
authors.lastname: Iannetti
mesh_terms: D000368:Aged; D050071:Bone Density Conservation Agents / Q000009:adverse effects*; D004164:Diphosphonates / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010020:Osteonecrosis / Q000139:chemically induced / Q000517:prevention & control*; D010083:Oxidants, Photochemical / Q000627:therapeutic use*; D010126:Ozone / Q000627:therapeutic use*; D014081:Tooth Extraction / Q000009:adverse effects
chemical_list: D050071:Bone Density Conservation Agents; D004164:Diphosphonates; D010083:Oxidants, Photochemical; D010126:Ozone