[Research advance of microRNA and stem cell].
OBJECTIVE
To review the advance in the experimental studies of microRNA (miRNA) and the relationship between miRNA and stem cells.


METHODS
The related literature was reviewed, and the research findings of miRNA and stem cell were summarized.


RESULTS
miRNA was non-coding small RNA (20-25 nt) involved in post-transcriptional change, that have been shown to regulate gene expressions. It has been reported that some kinds of miRNAs were likely important regulators for stem cells maintaining their state of self-renewal, and play key roles in their differentiation.


CONCLUSIONS
miRNA as regulation of gene expressions, can be served as a new way for stem cells research.
Gao
Jie
J
Department of Orthopedic Surgery, Tangdu Hospital, Fourth Military Medical University, Xi'an Shaanxi, 710038, PR China.
Yang
Tongtao
T
Qiu
Xiuchun
X
D000818:Animals; D002454:Cell Differentiation; D049109:Cell Proliferation; D053595:Embryonic Stem Cells / Q000166:cytology / Q000502:physiology; D005786:Gene Expression Regulation; D006801:Humans; D051379:Mice; D035683:MicroRNAs / Q000235:genetics / Q000378:metabolism; D013234:Stem Cells / Q000166:cytology / Q000502:physiology
D035683:MicroRNAs