title: [Laser skin resurfacing and fibrin sealing as successful treatment for facial angiofibromas in tuberous sclerosis].
abstract: Tuberous sclerosis complex (TSC) is an autosomal-dominant phacomatosis that manifests with visceral harmatomas, epilepsy, and mental retardation. Paranasal angiofibromas may cause bleeding and difficulties in nasal breathing and can stigmatise the individual. When treating TSC patients, the otolaryngologist must take patient compliance and the tendency to develop malignancies into account. We report on a 34-year-old woman who was treated successfully by a combination of CO(2) laser treatment and fibrin glue. The cosmetic results were excellent.
authors.affiliation: Universitätsklinik und Poliklinik für Hals-Nasen-Ohren-Heilkunde/Chirurgie, Rheinische Friedrich-Wilhelms-Universität, Sigmund-Freud-Str. 25, 53105, Bonn. annette.pantelis@ukb.uni-bonn.de
authors.forename: A
authors.initials: A
authors.lastname: Pantelis
authors.forename: F
authors.initials: F
authors.lastname: Bootz
authors.forename: T
authors.initials: T
authors.lastname: Kühnel
mesh_terms: D000328:Adult; D018322:Angiofibroma / Q000209:etiology / Q000628:therapy*; D003131:Combined Modality Therapy; D003646:Debridement / Q000379:methods*; D005260:Female; D015718:Fibrin Tissue Adhesive / Q000627:therapeutic use*; D006490:Hemostatics / Q000627:therapeutic use; D006801:Humans; D053685:Laser Therapy / Q000379:methods*; D019651:Plastic Surgery Procedures / Q000379:methods*; D012878:Skin Neoplasms / Q000209:etiology / Q000628:therapy*; D014014:Tissue Adhesives / Q000627:therapeutic use; D016896:Treatment Outcome; D014402:Tuberous Sclerosis / Q000150:complications / Q000628:therapy*
chemical_list: D015718:Fibrin Tissue Adhesive; D006490:Hemostatics; D014014:Tissue Adhesives