title: Should patients with pH-documented laryngopharyngeal reflux routinely undergo oesophagogastroduodenoscopy? A retrospective analysis.
abstract: OBJECTIVE
  Patients with laryngopharyngeal reflux uncommonly suffer from conditions associated with gastroesophageal reflux disease. However, in some laryngopharyngeal reflux patients, oesophagitis and Barrett's metaplasia can be diagnosed by oesophagogastroduodenoscopy. However, it is unclear which patients with laryngopharyngeal reflux would benefit from routine oesophagogastroduodenoscopy.
  
  
  METHODS
  Retrospective analysis.
  
  
  METHODS
  Analysis of the results of oesophagogastroduodenoscopy in 28 patients with pH-documented laryngopharyngeal reflux.
  
  
  RESULTS
  Oesophagogastroduodenoscopy showed oesophagitis in five patients (four with grade A, one with grade B), hiatus hernia in 10 patients (36 per cent), Barrett's metaplasia in two patients, Helicobacter pylori-associated chronic gastritis in two patients and gastric mucosal erosions in seven patients (25 per cent). In 13 patients, no abnormalities were detected (46 per cent). Barrett's metaplasia or grade B oesophagitis was diagnosed only in patients with heartburn as their main presenting symptom.
  
  
  CONCLUSIONS
  Oesophagogastroduodenoscopy is indicated in at least those laryngopharyngeal reflux patients reporting heartburn as their main complaint.
authors.affiliation: Department of Otorhinolaryngology, Head and Neck Surgery, Ludwig Maximilians University Munich, Germany. entdoc@gmx.net
authors.forename: O
authors.initials: O
authors.lastname: Reichel
authors.forename: W J
authors.initials: WJ
authors.lastname: Issing
mesh_terms: D001471:Barrett Esophagus / Q000175:diagnosis / Q000209:etiology; D016145:Endoscopy, Digestive System; D050782:Esophageal pH Monitoring; D004942:Esophagitis, Peptic / Q000175:diagnosis / Q000209:etiology; D005260:Female; D005764:Gastroesophageal Reflux / Q000150:complications* / Q000175:diagnosis; D006356:Heartburn / Q000209:etiology; D016481:Helicobacter Infections / Q000150:complications; D016480:Helicobacter pylori; D006551:Hernia, Hiatal / Q000150:complications / Q000175:diagnosis; D006801:Humans; D007013:Hypopharynx; D008297:Male; D008875:Middle Aged; D018579:Patient Selection; D010608:Pharyngeal Diseases / Q000150:complications* / Q000175:diagnosis; D012189:Retrospective Studies