title: Cost analysis of living donor liver transplantation: the first Italian economical data.
abstract: BACKGROUND
  Over a period of 30 months, the Niguarda Ca'Granda Hospital performed 12 living donor liver transplants (LDLT) on adult subjects using the split-liver technique and transplant of the right lobe. The purpose of this work is to evaluate the financial obligation that this technique will bring, the ethical and cultural aspects, and the mortality related to surgery on a healthy donor whose only reward is in the knowledge of having done everything possible for a loved family member.
  
  
  METHODS
  The analysis of the costs of the surgical process takes into account the simultaneous consideration of both types of patients: the donor and the recipient. The diagnostic course is subdivided into seven functional phases of the cost centers, and the transitory sequences of the foreseeable events of the entire process. The method used consists in the appraisal of all the clinical activities in chronological order several the centers of cost. The direct expenses are evaluated according to an analytical method, and the indirect costs has been carried out on the criterion of the activities of support to the process (management of the orders, recording and programming of the activities) and support to the organization (maintenance, management supplying and contests of contract, programming of the business production, management warehouses, supplyings, marketing and relations with the public).
  
  
  RESULTS
  The cost of all the patients evaluated that were not able to donate has been added to the direct expenses of 12 donor and 12 recipient patients, in all 30 patients, so as to shift the added expenses only to the donor patient, since these costs are not included in the typical costs of transplantation from a cadaver. The indirect cost calculated for each patient has been added to the direct costs of the donor and recipient patients. The total calculated cost of LDLT is 175, 210.78 Euros.
  
  
  CONCLUSIONS
  The analysis of the economical obligation that this practice brings is the starting point for an accurate evaluation of all the new technology that, in conjunction with the results of clinical efficacy and efficiency trials, is part of program of a larger scope to fulfil the general social principles of equity and justice.
authors.affiliation: Anaesthesiology and Intensive Care Unit II, Niguarda Ca' Granda Hospital, Milan, Italy. simonetta.passarani@ospedaleniguarda.it
authors.forename: S
authors.initials: S
authors.lastname: Passarani
authors.forename: L
authors.initials: L
authors.lastname: De Carlis
authors.forename: G
authors.initials: G
authors.lastname: Maione
authors.forename: A B
authors.initials: AB
authors.lastname: Alberti
authors.forename: L
authors.initials: L
authors.lastname: Bevilacqua
authors.forename: S
authors.initials: S
authors.lastname: Baraldi
mesh_terms: D003365:Costs and Cost Analysis; D006403:Hematologic Tests; D006801:Humans; D007558:Italy; D016031:Liver Transplantation / Q000191:economics* / Q000706:statistics & numerical data; D019520:Living Donors / Q000706:statistics & numerical data*