Hyperacute graft-vs.-host disease after related HLA-identical umbilical cord blood transplantation.
haGVHD has been described following bone marrow and peripheral blood stem cell transplantation and in a single case who received unrelated HLA mismatched CB. An unusual case of haGVHD following HLA 6/6-matched sibling CBT in a child with AML is presented. The development of haGVHD in a fully matched CBT and without precipitating factors may suggest the role of still undefined and perhaps individual contributory factors.
Kuskonmaz
Baris
B
Pediatric Hematology Unit, Faculty of Medicine, Hacettepe University, Ankara, Turkey.
Gocer
Safak
S
Ersoy-Ewans
Sibel
S
Cetin Ozman
Fatma
F
Cetin
Mualla
M
Uckan
Duygu
D
D000208:Acute Disease; D000328:Adult; D002675:Child, Preschool; D036101:Cord Blood Stem Cell Transplantation / Q000009:adverse effects*; D006086:Graft vs Host Disease / Q000209:etiology*; D006680:HLA Antigens / Q000276:immunology*; D006650:Histocompatibility Testing; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000628:therapy*; D018183:Transplantation Chimera; D019172:Transplantation Conditioning; D016896:Treatment Outcome
D006680:HLA Antigens