title: [Pancreatic carcinoma].
abstract: Aggressive tumor biology is the main characteristic of pancreatic cancer, in Germany the fourth leading cause of cancer death for females and the fifth leading cause for males. Due to late occurrence of symptoms and aggressive tumor growth, pancreatic cancer has equal incidence and mortality. Most malignant pancreatic tumours are ductal adenocarcinomas (85%). Surgical resection is the main therapeutic modality for pancreatic cancer, even though only a fraction of patients can undergo complete resection. Prognosis of pancreatic cancer remains poor even in completely resected patients; however, multimodal regimes might improve prognosis. Additionally, advances in surgical technique and perioperative management have reduced operative mortality and morbidity, especially in high-volume centers.
authors.affiliation: Sektion Chirurgische Onkologie, Klinik für Allgemein-, Viszeral- und Transplantationschirurgie, Chirurgische Universitätsklinik, Im Neuenheimer Feld 110, Heidelberg, Germany. juergen.weitz@med.uni-heidelberg.de
authors.forename: C
authors.initials: C
authors.lastname: Reissfelder
authors.forename: M
authors.initials: M
authors.lastname: Koch
authors.forename: M W
authors.initials: MW
authors.lastname: Büchler
authors.forename: J
authors.initials: J
authors.lastname: Weitz
mesh_terms: D005774:Gastrostomy / Q000379:methods; D006801:Humans; D015994:Incidence; D053208:Kaplan-Meier Estimate; D008197:Lymph Node Excision / Q000379:methods; D020360:Neoadjuvant Therapy; D009361:Neoplasm Invasiveness / Q000473:pathology; D009367:Neoplasm Staging; D010166:Palliative Care; D010179:Pancreas / Q000473:pathology; D010180:Pancreatectomy / Q000379:methods*; D010190:Pancreatic Neoplasms / Q000175:diagnosis / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D016577:Pancreaticoduodenectomy / Q000379:methods; D010193:Pancreaticojejunostomy / Q000379:methods; D011183:Postoperative Complications / Q000209:etiology / Q000401:mortality / Q000601:surgery; D011379:Prognosis