Mesoscopic model for tumor growth.
In this work, we propose a mesoscopic model for tumor growth to improve our understanding of the origin of the heterogeneity of tumor cells. In this sense, this stochastic formalism allows us to not only to reproduce but also explain the experimental results presented by Brú. A significant aspect found by the model is related to the predicted values for beta growth exponent, which capture a basic characteristic of the critical surface growth dynamics. According to the model, the value for growth exponent is between 0,25 and 0,5, which includes the value proposed by Kadar-Parisi-Zhang universality class (0,33) and the value proposed by Brú (0,375) related to the molecular beam epitaxy (MBE) universality class. This result suggests that the tumor dynamics are too complex to be associated to a particular universality class.
Izquierdo-Kulich
Elena
E
Departamento de Ingeniería Química. Facultad de Ingeniería Química. Instituto Superior Politécnico, CUJAE, Havana, Cuba. elenaik@fq.uh.cu
Nieto-Villar
José Manuel
JM
D048708:Cell Growth Processes / Q000502:physiology; D017709:Fractals; D008954:Models, Biological; D009369:Neoplasms / Q000473:pathology*; D013269:Stochastic Processes