title: [Bone metastases from unknown primary. FDG-PET detection of two synchronous tumors].
abstract: A 60-year-old woman presented with noncardiac chest pain over months and negative laboratory findings. Conventional imaging methods and bone scintigraphy detected bone lesions suggesting metastatic disease from an unknown primary tumor. An 18FDG-PET scan performed to orient the search for the primary tumor found focal lesions suggesting lymphoma and identified a focal thyroid lesion and a cervical lymph node accessible for biopsy. The biopsy of this lymph node incidentally detected a papillary differentiated thyroid cancer (DTC), since the existence of a non-Hodgkin's lymphoma was confirmed after a new biopsy. After confirming the presence of a lymphoma, 18FDG-PET enabled the initial staging of the tumor, the evaluation of the response to treatment, and follow-up for detection of recurrence. On the other hand, 18FDG-PET incidentally detected a DTC.
authors.affiliation: Unidad Diagnóstica de Gestión de Medicina Nuclear, Hospitales Universitarios Virgen del Rocío, Sevilla, España. nacho_cuenca@hotmail.com
authors.forename: J I
authors.initials: JI
authors.lastname: Cuenca Cuenca
authors.forename: I
authors.initials: I
authors.lastname: Borrego Dorado
authors.forename: J R
authors.initials: JR
authors.lastname: Rodríguez Rodríguez
authors.forename: E
authors.initials: E
authors.lastname: Navarro González
authors.forename: R
authors.initials: R
authors.lastname: Vázquez Albertino
mesh_terms: D001859:Bone Neoplasms / Q000000981:diagnostic imaging* / Q000556:secondary*; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000000981:diagnostic imaging*; D009382:Neoplasms, Unknown Primary / Q000000981:diagnostic imaging*; D049268:Positron-Emission Tomography; D019275:Radiopharmaceuticals
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18