title: [The first experience in application of melatonin (melaxen) for prophylaxis of the effects of magnetic storms on patients with cardiovascular pathology].
abstract: The aim of the investigation was to study a possibility to prevent the effects of geomagnetic storms (GMS) on cardiovascular patients. The subjects were patients with stage II to III essential hypertension and functional class II to III coronary artery disease, who were divided into three groups. Patients in group I received basic pharmacotherapy; patients in group II were treated with basic medications plus vitamin E; patients in group III received basic medications plus melatonin (melaxen). Vitamin E and melaxen were administered during a calm period, three days before a GMS, on the day of a GMS, and during three subsequent days. Besides clinico-instrumental examination, the patients were questioned for a range of clinical data. The results of the study substantiate the use of melatonin as a measure to prevent the influence of GMS.
authors.forename: S I
authors.initials: SI
authors.lastname: Rapoport
authors.forename: A V
authors.initials: AV
authors.lastname: Smirnova
authors.forename: N N
authors.initials: NN
authors.lastname: Naumcheva
authors.forename: S P
authors.initials: SP
authors.lastname: Gaĭdash
mesh_terms: D000975:Antioxidants / Q000627:therapeutic use*; D002318:Cardiovascular Diseases / Q000188:drug therapy* / Q000503:physiopathology* / Q000523:psychology; D004574:Electromagnetic Fields / Q000009:adverse effects*; D005260:Female; D006801:Humans; D006973:Hypertension / Q000209:etiology* / Q000517:prevention & control*; D008297:Male; D008550:Melatonin / Q000627:therapeutic use*; D008875:Middle Aged; D011788:Quality of Life / Q000523:psychology; D012720:Severity of Illness Index; D011795:Surveys and Questionnaires
chemical_list: D000975:Antioxidants; D008550:Melatonin