title: Relationship between cardiovagal modulation and psychotic state in patients with paranoid schizophrenia.
abstract: Disturbed autonomic nervous system (ANS) function in schizophrenia might contribute to increased cardiovascular mortality. We obtained heart rate variability indices from 40 unmedicated schizophrenic patients and 58 matched controls. Mainly we found that patients displaying stronger psychotic symptoms as assessed by the Brief Psychiatric Rating Scale exhibit more severe cardiac ANS disturbances compared with controls.
authors.affiliation: Department of Psychiatry and Psychotherapy, Friedrich-Schiller-University, Jena, Germany. Karl-Juergen.Baer@med.uni-jena.de
authors.forename: Karl-Jürgen
authors.initials: KJ
authors.lastname: Bär
authors.forename: Kirsten
authors.initials: K
authors.lastname: Wernich
authors.forename: Silke
authors.initials: S
authors.lastname: Boettger
authors.forename: Joachim
authors.initials: J
authors.lastname: Cordes
authors.forename: Michael Karl
authors.initials: MK
authors.lastname: Boettger
authors.forename: Stefan
authors.initials: S
authors.lastname: Löffler
authors.forename: Jürgen
authors.initials: J
authors.lastname: Kornischka
authors.forename: Marcus-Willi
authors.initials: MW
authors.lastname: Agelink
mesh_terms: D000208:Acute Disease; D000328:Adult; D014150:Antipsychotic Agents / Q000009:adverse effects; D001145:Arrhythmias, Cardiac / Q000139:chemically induced; D001342:Autonomic Nervous System Diseases / Q000453:epidemiology / Q000503:physiopathology*; D005260:Female; D006321:Heart / Q000502:physiology*; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D008297:Male; D009415:Nerve Net / Q000503:physiopathology*; D011618:Psychotic Disorders / Q000188:drug therapy / Q000453:epidemiology / Q000503:physiopathology*; D012563:Schizophrenia, Paranoid / Q000188:drug therapy / Q000453:epidemiology / Q000503:physiopathology*; D014630:Vagus Nerve / Q000502:physiology*
chemical_list: D014150:Antipsychotic Agents