An efficient scalable synthesis of 2,3-epoxypropyl phenylhydrazones.
A series of mono and di-N-2,3-epoxypropyl N-phenylhydrazones have been prepared on a large scale by reaction of the corresponding N-phenylhydrazones of 9-ethyl-3-carbazolecarbaldehyde, 9-ethyl-3,6-carbazoledicarbaldehyde, 4-dimethyl-amino-, 4-diethylamino-, 4-benzylethylamino-, 4-(diphenylamino)-, 4-(4,4-4'-dimethyl-diphenylamino)-, 4-(4-formyldiphenylamino)- and 4-(4-formyl-4'-methyldiphenyl-amino)benzaldehyde with epichlorohydrin in the presence of KOH and anhydrous Na(2)SO(4).
Getautis
Vytautas
V
Department of Organic Chemistry, Kaunas University of Technology, LT-50270 Kaunas, Lithuania. vytautas.getautis@ktu.lt
Daskeviciene
Maryte
M
Malinauskas
Tadas
T
Stanisauskaite
Albina
A
Stumbraite
Jolanta
J
D004526:Efficiency; D004811:Epichlorohydrin / Q000737:chemistry; D006571:Heterocyclic Compounds / Q000138:chemical synthesis; D006835:Hydrazones / Q000138:chemical synthesis*; D008954:Models, Biological
D006571:Heterocyclic Compounds; D006835:Hydrazones; C012483:phenylhydrazone; D004811:Epichlorohydrin