Copper-catalyzed alkene aziridination with N-tosyloxycarbamates.
Pyridine copper complexes were found as active catalysts for the intramolecular aziridination of allylic N-tosyloxycarbamates and the intermolecular aziridination of styrenes with trichloroethyl N-tosyloxycarbamates. Free aziridines were easily obtained by basic deprotection of the trichloroethyl group.
Lebel
Hélène
H
Département de Chimie, Université de Montréal, Station Downtown, Montréal, Québec, Canada. helene.lebel@umontreal.ca
Lectard
Sylvain
S
Parmentier
Michaël
M
D000475:Alkenes / Q000138:chemical synthesis* / Q000737:chemistry; D001388:Aziridines / Q000737:chemistry*; D002219:Carbamates / Q000737:chemistry*; D002384:Catalysis; D003300:Copper; D015394:Molecular Structure; D010100:Oxygen / Q000737:chemistry*; D013343:Styrenes / Q000737:chemistry
D000475:Alkenes; D001388:Aziridines; D002219:Carbamates; D013343:Styrenes; D003300:Copper; D010100:Oxygen