[A case report of misdiagnosed mantle cell lymphoma].
Mantle cell lymphoma (MCL) is a rare group of non-Hodgkin's lymphoma (NHL), which is difficult to discriminate from other subtype of small lymphocytic lymphoma in morphologic appearance. In order to enhance the understanding of MCL, a case of MCL first diagnosed as follicular lymphoma (FL) was reported. The clinical and laboratory characteristics of MCL were analyzed and summarized. The results showed that the findings of flow cytometry (FCM) and immunohistochemical staining technique were compatible with the diagnosis of MCL. Cytogenetic analysis can detect multiple types of chromosomal abnormalities, including t (11; 14). In conclusion, MCL is a disease which diagnosis is difficulty confirmed. Interphase fluorescence in situ hybridization, multiplex fluorescence in situ hybridization, FCM and immunohistochemical staining technique play important roles in the diagnosis of MCL.
Yu
Hui
H
Department of Hematology, The First Affiliated Hospital of Nanjing Medical University, Jiangsu Province People Hospital, Nanjing 210029, China.
Xu
Wei
W
Wu
Yu-Jie
YJ
Cheng
Yue-Xin
YX
Qiu
Hai-Rong
HR
Zhang
Su-Jiang
SJ
Sheng
Rui-Lan
RL
Li
Jian-Yong
JY
D003951:Diagnostic Errors; D005434:Flow Cytometry; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D020522:Lymphoma, Mantle-Cell / Q000175:diagnosis*; D008297:Male; D008875:Middle Aged