title: Organocatalysts wrapped around by poly(ethylene glycol)s (PEGs): a unique host-guest system for asymmetric Michael addition reactions.
abstract: Asymmetric Michael addition reactions of unmodified ketones to nitroalkenes were performed in PEGs catalyzed by novel pyrrolidinyl-thioimidazolium salts to give products in up to 97% yield and 99% enantioselectivity; ESI mass spectrometric detection for the first time gave evidence of the presence of the PEG-organocatalyst host-guest complex.
authors.affiliation: State Key Laboratory Breeding Base of Green Chemistry-Synthesis Technology, Zhejiang University of Technology, Hangzhou, China.
authors.forename: Dan Qian
authors.initials: DQ
authors.lastname: Xu
authors.forename: Shu Ping
authors.initials: SP
authors.lastname: Luo
authors.forename: Yi Feng
authors.initials: YF
authors.lastname: Wang
authors.forename: Ai Bao
authors.initials: AB
authors.lastname: Xia
authors.forename: Hua Dong
authors.initials: HD
authors.lastname: Yue
authors.forename: Li Ping
authors.initials: LP
authors.lastname: Wang
authors.forename: Zhen Yuan
authors.initials: ZY
authors.lastname: Xu
mesh_terms: D000475:Alkenes / Q000138:chemical synthesis*; D002384:Catalysis; D007202:Indicators and Reagents; D007659:Ketones / Q000138:chemical synthesis*; D009682:Magnetic Resonance Spectroscopy; D011092:Polyethylene Glycols / Q000737:chemistry*; D011759:Pyrrolidines; D021241:Spectrometry, Mass, Electrospray Ionization; D013055:Spectrophotometry, Infrared; D013237:Stereoisomerism; D014961:X-Ray Diffraction
chemical_list: D000475:Alkenes; D007202:Indicators and Reagents; D007659:Ketones; D011759:Pyrrolidines; D011092:Polyethylene Glycols