The 1,2,3-triazole ring as a peptido- and olefinomimetic element: discovery of click vanilloids and cannabinoids.
Appendino
Giovanni
G
Dipartimento di Scienze Chimiche, Alimentari, Farmaceutiche e Farmacologiche, Università del Piemonte Orientale, Via Bovio 6, 28100 Novara, Italy. appendino@pharm.unipmn.it
Bacchiega
Sara
S
Minassi
Alberto
A
Cascio
Maria Grazia
MG
De Petrocellis
Luciano
L
Di Marzo
Vincenzo
V
D002186:Cannabinoids / Q000737:chemistry*; D002211:Capsaicin / Q000031:analogs & derivatives* / Q000737:chemistry*; D043884:Receptor, Cannabinoid, CB1 / Q000037:antagonists & inhibitors*; D050916:TRPV Cation Channels / Q000819:agonists / Q000037:antagonists & inhibitors*; D014230:Triazoles / Q000737:chemistry*
D002186:Cannabinoids; D043884:Receptor, Cannabinoid, CB1; D050916:TRPV Cation Channels; C494484:TRPV1 receptor; D014230:Triazoles; D002211:Capsaicin