title: Community-acquired pneumonia complications in a patient with hereditary glucose-6-phosphate dehydrogenase deficiency.
abstract: Severe complications of lower respiratory tract infection in a patient with hereditary glucose-6-phosphate dehydrogenase (G-6-PD) deficiency may occur. The case of a 68-year-old man with hereditary glucose-6-phosphate dehydrogenase (G6PD) deficiency who developed severe haemolysis after community-acquired pneumonia is presented. G6PD deficiency in our patient was diagnosed during childhood. We observed complications of community-acquired pneumonia: empyema, haemolytic crisis and renal failure. Videopleuroscopy and pleural drainage were successfully performed. Community-acquired streptococcal pneumonia may also lead to haemolysis in G6PD deficient patients. Acute haemolysis, severe anaemia and renal insufficiency secondary to haemoglobinuria can be observed. Severe purulent complications of pneumonia in G6PD deficient patients may suggest granulocyte function impairment.
authors.affiliation: 2nd Department of Respiratory Medicine, Institute of Tuberculosis and Lung Diseases, Warsaw, Poland. a.nowinski@igichp.edu.pl
authors.forename: Adam
authors.initials: A
authors.lastname: Nowiński
authors.forename: Ewa
authors.initials: E
authors.lastname: Jabłońska-Skwiecińska
authors.forename: Emil
authors.initials: E
authors.lastname: Wojda
authors.forename: Przemysław
authors.initials: P
authors.lastname: Bieleń
authors.forename: Jakub
authors.initials: J
authors.lastname: Ptak
authors.forename: Paweł
authors.initials: P
authors.lastname: Sliwinski
authors.forename: Dorota
authors.initials: D
authors.lastname: Górecka
mesh_terms: D000368:Aged; D017714:Community-Acquired Infections / Q000150:complications; D005955:Glucosephosphate Dehydrogenase Deficiency / Q000150:complications*; D006801:Humans; D008297:Male; D018410:Pneumonia, Bacterial / Q000150:complications* / Q000000981:diagnostic imaging*; D011859:Radiography