Left-right information flow in the brain during EEG arousals.
In disorders such as sleep apnea, sleep is fragmented with frequent EEG-arousal (EEGA) as determined via changes in the sleep-electroencephalogram. EEGA is a poorly understood, complicated phenomenon which is critically important in studying the mysteries of sleep. In this paper we study the information flow between the left and right hemispheres of the brain during the EEGA as manifested through inter-hemispheric asynchrony (IHA) of the surface EEG. EEG data (using electrodes A1/C4 and A2/C3 of international 10-20 system) was collected from 5 subjects undergoing routine polysomnography (PSG). Spectral correlation coefficient (R) was computed between EEG data from two hemispheres for delta-delta(0.5-4 Hz), theta-theta(4.1-8 Hz), alpha-alpha(8.1-12 Hz) & beta-beta(12.1-25 Hz) frequency bands, during EEGA events. EEGA were graded in 3 levels as (i) micro arousals (3-6 s), (ii) short arousals (6.1-10 s), & (iii) long arousals (10.1-15 s). Our results revealed that in beta band, IHA increases above the baseline after the onset of EEGA and returns to the baseline after the conclusion of event. Results indicated that the duration of EEGA events has a direct influence on the onset of IHA. The latency (L) between the onset of arousals and IHA were found to be L=2 +/- 0.5 s (for micro arousals), 4 +/- 2.2 s (short arousals) and 6.5 +/- 3.6 s (long arousals).
Swarnkar
V
V
Sch. of Inf. Technol. & Electr. Eng., Queensland Univ., Brisbane, Qld, Australia.
Abeyratne
Udantha R
UR
Karunajeewa
A S
AS
D000465:Algorithms; D001143:Arousal; D016477:Artifacts; D001931:Brain Mapping; D054022:Cerebrum / Q000033:anatomy & histology* / Q000473:pathology; D004566:Electrodes; D004569:Electroencephalography / Q000379:methods*; D006801:Humans; D017286:Polysomnography / Q000295:instrumentation* / Q000379:methods; D012890:Sleep; D012891:Sleep Apnea Syndromes; D012894:Sleep Stages; D012895:Sleep, REM; D013997:Time Factors; D014851:Wakefulness