[Influencing factors on dampproof effect of microcapsules and study on mechanism].
OBJECTIVE
The influence of spray drying technology on the damp proof effect of microcapsules and the mechanism were studied.


METHODS
The microcapsules prepared with different spray drying parameters have been put in certain surroundings for 12 hours, then the hygroscopic curves were gotten; the mechanism was studied from the following aspects: solvent residue, film's shrink and particle size.


RESULTS
The damp proof effect enhanced with the increase of inlet air temperature and the decrease of flow rate and air pressure. The properties of the wall, the solvent residue and particle size can influence the damp proof effect of the microcapsules.


CONCLUSIONS
The physical properties of microcapsules are different because of the different spray drying parameters, which lead to different damp proof effect of microcapsules.
Feng
Yi
Y
Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China. fyi@vip.sina.com
Liu
Yi
Y
Xu
De-sheng
DS
D000180:Acrylic Resins; D002214:Capsules; D003890:Desiccation / Q000379:methods*; D004339:Drug Compounding / Q000379:methods*; D027443:Lindera / Q000737:chemistry; D010316:Particle Size; D010946:Plants, Medicinal / Q000737:chemistry; D012997:Solvents; D013634:Tannins / Q000008:administration & dosage* / Q000302:isolation & purification; D013696:Temperature
D000180:Acrylic Resins; D002214:Capsules; C446821:Eudragit L100-55; D012997:Solvents; D013634:Tannins