Spectroscopic evidence for a high-spin Br-Fe(IV)-oxo intermediate in the alpha-ketoglutarate-dependent halogenase CytC3 from Streptomyces.
Fujimori
Danica Galonić
DG
Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Cambridge, MA 02115, USA.
Barr
Eric W
EW
Matthews
Megan L
ML
Koch
Gretchen M
GM
Yonce
J Ryan
JR
Walsh
Christopher T
CT
Bollinger
J Martin
JM
Krebs
Carsten
C
Riggs-Gelasco
Pamela J
PJ
D001966:Bromine / Q000737:chemistry*; D002384:Catalysis; D003574:Cytochrome c Group / Q000737:chemistry*; D005290:Ferric Compounds / Q000138:chemical synthesis / Q000737:chemistry*; D054879:Halogenation; D007656:Ketoglutaric Acids / Q000737:chemistry*; D008968:Molecular Conformation; D010084:Oxidation-Reduction; D010088:Oxidoreductases / Q000737:chemistry*; D013057:Spectrum Analysis / Q000379:methods*; D013237:Stereoisomerism; D013302:Streptomyces / Q000201:enzymology*; D014965:X-Rays
D003574:Cytochrome c Group; D005290:Ferric Compounds; D007656:Ketoglutaric Acids; C017165:cytochrome c(3); D010088:Oxidoreductases; D001966:Bromine