title: The value of medical interventions for lung cancer in the elderly: results from SEER-CMHSF.
abstract: BACKGROUND
  Lung cancer is the leading source of cancer mortality and spending. However, the value of spending on the treatment of lung cancer has not been conclusively demonstrated. The authors evaluated the value of medical care between 1983 and 1997 for nonsmall cell lung cancer in the elderly US population.
  
  
  METHODS
  The authors used Surveillance, Epidemiology, and End Results (SEER) data to calculate life expectancy after diagnosis over the period 1983 to 1997. Direct costs for nonsmall cell lung cancer detection and treatment were determined by using Part A and Part B reimbursements from the Continuous Medicare History Sample File (CMHSF) data. The CMHSF and SEER data were linked to calculate lifetime treatment costs over the time period of interest.
  
  
  RESULTS
  Life expectancy improved minimally, with an average increase of approximately 0.60 months. Total lifetime lung cancer spending rose by approximately $20,157 per patient in real, ie, adjusted for inflation, 2000 dollars from the early 1980s to the mid-1990s, for a cost-effectiveness ratio of $403,142 per life year (LY). The cost-effectiveness ratio was $143,614 for localized cancer, $145,861 for regional cancer, and $1,190,322 for metastatic cancer.
  
  
  CONCLUSIONS
  The cost-effectiveness ratio for nonsmall cell lung cancer was higher than traditional thresholds used to define cost-effective care. The most favorable results were for persons diagnosed with early stage cancer. These results suggested caution when encouraging more intensive care for lung cancer patients without first considering the tradeoffs with the costs of this therapy and its potential effects on mortality and/or quality of life.
authors.affiliation: Harvard Interfaculty Program for Health Systems Improvement, Department of Economics, Harvard University, Cambridge, Massachusetts 02145, USA. rwoodwar@nber.org
authors.forename: Rebecca M
authors.initials: RM
authors.lastname: Woodward
authors.forename: Martin L
authors.initials: ML
authors.lastname: Brown
authors.forename: Susan T
authors.initials: ST
authors.lastname: Stewart
authors.forename: Kathleen A
authors.initials: KA
authors.lastname: Cronin
authors.forename: David M
authors.initials: DM
authors.lastname: Cutler
mesh_terms: D017668:Age of Onset; D000368:Aged; D000369:Aged, 80 and over; D002289:Carcinoma, Non-Small-Cell Lung / Q000191:economics*; D003362:Cost-Benefit Analysis; D005260:Female; D017048:Health Care Costs; D006801:Humans; D008017:Life Expectancy; D008175:Lung Neoplasms / Q000191:economics*; D008297:Male; D018426:SEER Program