The presence of a single PML-RARA isoform lacking exon 5 in FISH-negative APL samples.
Ashur-Fabian
O
O
Trakhtenbrot
L
L
Dominissini
D
D
Koren-Michowitz
M
M
Nagler
A
A
Rechavi
G
G
Amariglio
N
N
D017398:Alternative Splicing; D005091:Exons / Q000235:genetics*; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D015473:Leukemia, Promyelocytic, Acute / Q000235:genetics* / Q000628:therapy; D009364:Neoplasm Recurrence, Local / Q000235:genetics; D015514:Oncogene Proteins, Fusion / Q000235:genetics* / Q000378:metabolism; D020033:Protein Isoforms; D020133:Reverse Transcriptase Polymerase Chain Reaction
D015514:Oncogene Proteins, Fusion; D020033:Protein Isoforms; C093476:promyelocytic leukemia-retinoic acid receptor alpha fusion oncoprotein