Five nitro-phenyl compounds from the South China Sea mangrove fungus.
A novel nitro-phenyl glucoside (1) was isolated from mangrove endophytic fungus (fungus B60), collected from the Shenzhen mangrove Acanthus ilicifolius linn. Four related nitro-phenyl compounds (2-5) were also obtained, which were isolated for the first time as natural products. Their structures were established on the basis of NMR spectroscopic, mass spectrometric data and some chemical transformations. In the preliminary bioassay, compound 1 had a slight inhibitory effect on alpha-glucosidase with an IC(50) of 160.3 microM.
Shao
Chang-Lun
CL
School of Chemistry and Chemical Engineering, Sun Yat-Sen (Zhongshan) University, Guangzhou, China.
Guo
Zhi-Yong
ZY
Xia
Xue-Kui
XK
Liu
Yan
Y
Huang
Zhong-Jing
ZJ
She
Zhi-Gang
ZG
Lin
Yong-Cheng
YC
Zhou
Shi-Ning
SN
D005658:Fungi / Q000737:chemistry*; D005960:Glucosides / Q000737:chemistry / Q000302:isolation & purification*; D009682:Magnetic Resonance Spectroscopy; D043982:Rhizophoraceae / Q000382:microbiology*; D013056:Spectrophotometry, Ultraviolet
D005960:Glucosides