title: Studies on terpenoids produced by actinomycetes: oxaloterpins A, B, C, D, and E, diterpenes from Streptomyces sp. KO-3988.
abstract: Following screening for terpenoids produced by Streptomyces sp. KO-3988, five new diterpenes named oxaloterpins A (1), B (2), C (3), D (4), and E (5) together with the known viguiepinone (6) were isolated from culture broth, and their structures were established on the basis of extensive NMR and MS analyses. The absolute configuration of oxaloterpin A was determined by the modified Mosher's method as 3 R, 5 S, 8 S, 10 R, 13 S.
authors.affiliation: Faculty of Applied Bioscience, Tokyo University of Agriculture, Tokyo 156-8502, Japan.
authors.forename: Keiichiro
authors.initials: K
authors.lastname: Motohashi
authors.forename: Ryoko
authors.initials: R
authors.lastname: Ueno
authors.forename: Masayuki
authors.initials: M
authors.lastname: Sue
authors.forename: Kazuo
authors.initials: K
authors.lastname: Furihata
authors.forename: Takuo
authors.initials: T
authors.lastname: Matsumoto
authors.forename: Tohru
authors.initials: T
authors.lastname: Dairi
authors.forename: Satoshi
authors.initials: S
authors.lastname: Omura
authors.forename: Haruo
authors.initials: H
authors.lastname: Seto
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D001412:Bacillus subtilis / Q000187:drug effects; D018360:Crystallography, X-Ray; D004224:Diterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D008968:Molecular Conformation; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D013211:Staphylococcus aureus / Q000187:drug effects; D013237:Stereoisomerism; D013302:Streptomyces / Q000737:chemistry*
chemical_list: D000900:Anti-Bacterial Agents; D004224:Diterpenes