title: A little knowledge: caregiver burden in schizophrenia in Malawi.
abstract: OBJECTIVE
  To determine the relationship between schizophrenia knowledge and burden of care among caregivers of people with schizophrenia in Mzuzu, Malawi.
  
  
  METHODS
  We recruited 90 patients and 90 caregivers to a randomized, controlled trial of group caregiver education in schizophrenia. At baseline, we administered the Family Questionnaire, which measures caregivers' knowledge of biomedical and psychosocial aspects of schizophrenia. We measured caregiver burden with the Involvement Evaluation Questionnaire. Using multivariate analysis, we examined the relationship between knowledge and burden, controlling for other patient and caregiver variables. We hypothesised that knowledge and burden would be inversely related.
  
  
  RESULTS
  Caregiver burden was associated with knowledge (p = 0.001), but contrary to our hypothesis, greater knowledge was associated with greater burden.
  
  
  CONCLUSIONS
  In this population, knowledge about schizophrenia was associated with higher caregiver burden. This does not prove that knowledge causes burden, but suggests that cultural factors may mediate the relationship between knowledge and burden, and that care is needed when introducing caregiver education in new cultures.
authors.affiliation: Stanley Research Unit, St John of God Community Mental Health Services, Mzuzu, Malawi.
authors.forename: Anthony
authors.initials: A
authors.lastname: Sefasi
authors.forename: Niall
authors.initials: N
authors.lastname: Crumlish
authors.forename: Prince
authors.initials: P
authors.lastname: Samalani
authors.forename: Anthony
authors.initials: A
authors.lastname: Kinsella
authors.forename: Eadbhard
authors.initials: E
authors.lastname: O'Callaghan
authors.forename: Harris
authors.initials: H
authors.lastname: Chilale
mesh_terms: D000328:Adult; D017028:Caregivers / Q000523:psychology; D017281:Cost of Illness; D005260:Female; D006266:Health Education; D007722:Health Knowledge, Attitudes, Practice; D006801:Humans; D008295:Malawi; D008297:Male; D015999:Multivariate Analysis; D016032:Randomized Controlled Trials as Topic; D012559:Schizophrenia