title: Histopathological evaluation of pulpotomy with Er,Cr:YSGG laser vs formocresol.
abstract: The purpose of this study was to histologically investigate whether pulpotomy with Er,Cr:YSGG laser is an acceptable alternative for formocresol. Pulpotomy of 48 dog's primary canine teeth was performed with formocresol or Er,Cr:YSGG laser. Histological evaluations on hematoxylin and eosin-stained pulp tissues were made by an optical microscope 7 or 60 days later. Statistical analysis was performed with Fisher's exact test, Mann-Whitney U test, and Student's t test. Seven days after pulpotomy, samples treated with laser had significantly favorable histological features in the following measures: continuity of odontoblastic layer (P<0.001), presence of hemorrhage (P<0.008), amount of inflammation (P<0.002), tissue necrosis (P<0.001), internal resorption (P<0.002), level of vascularization (P<0.002), and size of abscess (P<0.041). Similar results were observed 60 days after pulpotomy, except that the differences were not mostly significant due to natural exfoliation of 16 teeth. In conclusion, Er,Cr:YSGG laser system is an acceptable alternative for formocresol in pulpotomy of deciduous teeth.
authors.affiliation: Department of Pediatrics, Shaheed Beheshti School of Dentistry, Tehran, Iran.
authors.forename: Lida
authors.initials: L
authors.lastname: Toomarian
authors.forename: Reza
authors.initials: R
authors.lastname: Fekrazad
authors.forename: Davood
authors.initials: D
authors.lastname: Sharifi
authors.forename: Mojdeh
authors.initials: M
authors.lastname: Baghaei
authors.forename: Hessam
authors.initials: H
authors.lastname: Rahimi
authors.forename: Behnam
authors.initials: B
authors.lastname: Eslami
mesh_terms: D000818:Animals; D003782:Dental Pulp / Q000187:drug effects / Q000528:radiation effects*; D004285:Dogs; D005566:Formocresols / Q000627:therapeutic use*; D006416:Hematoxylin / Q000528:radiation effects*; D053685:Laser Therapy / Q000295:instrumentation* / Q000379:methods; D053844:Lasers, Solid-State; D008297:Male; D023421:Models, Animal; D009804:Odontoblasts / Q000528:radiation effects; D010865:Pilot Projects; D011672:Pulpotomy / Q000295:instrumentation* / Q000379:methods; D014094:Tooth, Deciduous / Q000528:radiation effects*; D015034:Zinc Oxide
chemical_list: D005566:Formocresols; C031025:formocresol; D015034:Zinc Oxide; D006416:Hematoxylin