Mycobacterium bovis BCG vertebral osteomyelitis after intravesical BCG therapy, diagnosed by PCR-based genomic deletion analysis.
We report a case of Mycobacterium bovis BCG vertebral osteomyelitis 1.8 years after intravesical BCG therapy for bladder cancer. We differentiated BCG from other Mycobacterium tuberculosis complex members by PCR analysis of deletion regions and started an appropriate chemotherapy regimen resulting in the remission of symptoms within 1 month.
Nikaido
Takuya
T
Department of Orthopedics, Fukushima Medical University, Fukushima, Japan.
Ishibashi
Kei
K
Otani
Koji
K
Yabuki
Shoji
S
Konno
Shinichi
S
Mori
Shuichi
S
Ohashi
Kazutaka
K
Ishida
Takashi
T
Nakano
Michiko
M
Yamaguchi
Osamu
O
Suzutani
Tatsuo
T
Kikuchi
Shinichi
S
D000369:Aged, 80 and over; D000995:Antitubercular Agents / Q000627:therapeutic use; D004269:DNA, Bacterial / Q000235:genetics; D006801:Humans; D008159:Lumbar Vertebrae / Q000000981:diagnostic imaging / Q000473:pathology; D008297:Male; D009163:Mycobacterium bovis / Q000302:isolation & purification*; D010019:Osteomyelitis / Q000188:drug therapy / Q000382:microbiology*; D016133:Polymerase Chain Reaction / Q000379:methods; D011859:Radiography; D014376:Tuberculosis / Q000150:complications* / Q000188:drug therapy / Q000382:microbiology*
D000995:Antitubercular Agents; D004269:DNA, Bacterial