title: [Depressive symptoms as a risk factor for polypharmacy in patients over 60 years of age].
abstract: OBJECTIVE
  To determine the association between depressive symptoms not identified by the family physician and polypharmacy in patients over 60 years old.
  
  
  METHODS
  A case-control design with non-probabilistic sampling.
  
  
  METHODS
  > or = 60 years old both sexes, without disease or with one disease-balanced illness, and with reliable recording in chart by the last 12 month.
  
  
  METHODS
  cognitive deterioration, obstructive chronic lung disease, cardiopathy, infarct record, alcoholism, smoking addiction and functional dependence's. Elimination criteria: depression's previous diagnoses and hospitalization during a year before the study. The cases were patients who have simultaneously received 4 o more pharmacologic prescriptions in 5 of 6 last medical visits. The controls were patients who have simultaneously received 3 o less pharmacologic prescriptions in 5 of 6 last medical visits. Depressive symptoms: grading > or = 6 (Yesavage and Brink scale).
  
  
  RESULTS
  200 patients per group, aged 69 +/- 6 years agreed to participate. Logistics regression (OR;CI(95%)): hypertension (6.0;3.6-10.3), diabetes mellitus type 2 (3.7;2.3-5.9), depression (2.1;1.2-3.4), and female sex (1.7;1.1-2.7).
  
  
  CONCLUSIONS
  Hypertension, diabetes mellitus type 2, depressive symptoms not identified by the family physician, and female sex are risk factors for polypharmacy in the elderly.
authors.affiliation: Unidad de Medicina Familiar No. 77, Instituto Mexicano del Seguro Social Edo. de México, México.
authors.forename: José Antonio
authors.initials: JA
authors.lastname: Granados-Ponce
authors.forename: María Luisa
authors.initials: ML
authors.lastname: Peralta-Pedrero
authors.forename: Catarina
authors.initials: C
authors.lastname: Munguía-Miranda
authors.forename: Juan Manuel
authors.initials: JM
authors.lastname: López-Carmona
authors.forename: Armando
authors.initials: A
authors.lastname: Avila-Leyva
authors.forename: Raymundo
authors.initials: R
authors.lastname: Rodríguez-Moctezuma
mesh_terms: D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D001786:Blood Glucose / Q000032:analysis; D016022:Case-Control Studies; D003863:Depression / Q000175:diagnosis; D003924:Diabetes Mellitus, Type 2; D005260:Female; D006801:Humans; D006973:Hypertension; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D010821:Physicians, Family; D019338:Polypharmacy; D012307:Risk Factors; D012737:Sex Factors
chemical_list: D001786:Blood Glucose