title: Distal radius bone mineral density estimation using the filling factor of trabecular bone in the x-ray image.
abstract: Osteoporosis is characterized by an abnormal loss of bone mineral content, which leads to a tendency to non-traumatic bone fractures or to structural deformations of bone. Thus, bone density measurement has been considered as a most reliable method to assess bone fracture risk due to osteoporosis. In past decades, X-ray images have been studied in connection with the bone mineral density estimation. However, the estimated bone mineral density from the X-ray image can undergo a relatively large accuracy or precision error. The most relevant origin of the accuracy or precision error may be unstable X-ray image acquisition condition. Thus, we focus our attentions on finding a bone mineral density estimation method that is relatively insensitive to the X-ray image acquisition condition. In this paper, we develop a simple technique for distal radius bone mineral density estimation using the trabecular bone filling factor in the X-ray image and apply the technique to the wrist X-ray images of 20 women. Estimated bone mineral density shows a high linear correlation with a dual-energy X-ray absorptiometry (r=0.87).
authors.affiliation: IT-BT Res. Group, Electron. & Telecommun. Res. Inst., Daejeon, Korea.
authors.forename: Sooyeul
authors.initials: S
authors.lastname: Lee
authors.forename: Ji-Wook
authors.initials: JW
authors.lastname: Jeong
authors.forename: Jeong Won
authors.initials: JW
authors.lastname: Lee
authors.forename: Done-Sik
authors.initials: DS
authors.lastname: Yoo
authors.forename: Seunghwan
authors.initials: S
authors.lastname: Kim
mesh_terms: D015502:Absorptiometry, Photon / Q000379:methods*; D000465:Algorithms; D015519:Bone Density; D005260:Female; D006801:Humans; D010024:Osteoporosis / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D011857:Radiographic Image Interpretation, Computer-Assisted / Q000379:methods*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013977:Tibia / Q000000981:diagnostic imaging* / Q000503:physiopathology*