Weight gain with atypical antipsychotics: evidence and insights.
Weight gain associated with antipsychotic medication can be a barrier to the overall improvement of mental health patients due to a discontinuation of treatment. The goal of this article is to establish a better understanding regarding the mechanisms of antipsychotic medications and their associated risk of weight gain, obesity, and subsequent mortality and morbidity. Additionally, the need to closely monitor patients' lifestyles and homeostatic components in order to prevent weight gain or facilitate weight loss is emphasized.
Henderson
David C
DC
Department of Psychiatry, Harvard Medical School, Boston, USA. dchenderson@partners.org
D014150:Antipsychotic Agents / Q000009:adverse effects*; D001714:Bipolar Disorder / Q000188:drug therapy; D004730:Endothelium, Vascular / Q000187:drug effects / Q000503:physiopathology; D006801:Humans; D007333:Insulin Resistance; D009765:Obesity; D010349:Patient Compliance; D012559:Schizophrenia / Q000188:drug therapy; D015430:Weight Gain
D014150:Antipsychotic Agents