Enantioselective synthesis of the C8-C20 segment of curvicollide C.
The enantioselective synthesis of the C8-C20 fragment of curvicollide C has been accomplished. A catalytic asymmetric Claisen rearrangement (CAC), a diastereoselective methyl cupration of an alkynoate, and a Julia-Kocienski olefination served as key C/C-connecting transformations.
Körner
Marleen
M
Fachbereich Chemie, Universität Dortmund, D-44227 Dortmund, Germany.
Hiersemann
Martin
M
D007783:Lactones / Q000138:chemical synthesis* / Q000737:chemistry; D008968:Molecular Conformation; D013237:Stereoisomerism
D007783:Lactones; C496156:curvicollide C