title: Development of a support tool for multi-agent based biological modeling.
abstract: In late years physiomic modeling of biological organisms are performed flourishingly. However enormous labor is required for performing such a large-scale and complicated biological model development. We were aimed at developing a software tool which could reduce a burden of the model developers who try to build such a model. At first we defined the data structure that could describe structure and functions of modules consisting of biological organisms. Then we designed the base classes which expressed the data structure. A whole model would be realized by connecting a number of modules that realize the functioning of the base classes. By applying our tool to concrete model developments for a cardiac cell and a single ionic channel, we examined utility and effectiveness of the tool for modeling on a multi-scale.
authors.affiliation: Graduate Sch. of Eng. Sci., Osaka Univ. kawazu@bpe.es.osaka-u.ac.jp
authors.forename: Toshiro
authors.initials: T
authors.lastname: Kawazu
authors.forename: Shinsuke
authors.initials: S
authors.lastname: Odai
authors.forename: Noriko
authors.initials: N
authors.lastname: Shibuya
authors.forename: Taishin
authors.initials: T
authors.lastname: Nomura
mesh_terms: D000818:Animals; D001695:Biology / Q000379:methods; D002468:Cell Physiological Phenomena; D003198:Computer Simulation; D006321:Heart / Q000502:physiology; D008954:Models, Biological; D008955:Models, Cardiovascular; D009206:Myocardium / Q000166:cytology; D012984:Software