[Ischemic mitral regurgitation: contributions of exercise echocardiography and new therapeutic perspectives].
The ischemic mitral regurgitation is defined by a left ventricular muscle disease affecting the function of normal mitral valve leaflets. This kind of mitral regurgitation is founded in about 20% of the ischemic cardiomyopathy and is attributed to the remodelling of the left ventricular shape. Its development is associated to a significantly worse prognosis. Frequently this ischemic mitral regurgitation will be associated to episode of acute heart failure decompensation. Its diagnosis is sometimes challenging as the degree of regurgitation might be extremely variable and affected by loading conditions. Echocardiography and especially exercise stress echocardiography has been demonstrated as an extremely powerful tool for its diagnosis and the prognostic evaluation. Its treatment should include the pharmacological treatment of the chonic heart failure and we are still waiting data in regard to the prognostic role of surgical mitral valvuloplastie. Works are still ongoing.
Martins
R-P
RP
Département de cardiologie et maladies vasculaires, centre cardiopneumologique, CHU Pontchaillou, 2, rue Henri-Le-Guilloux, 35033 Rennes cedex 09, France.
Baruteau
A-E
AE
Donal
E
E
de Place
C
C
Daubert
J-C
JC
Mabo
P
P
D025401:Echocardiography, Stress / Q000379:methods*; D005080:Exercise Test; D006333:Heart Failure / Q000209:etiology; D006801:Humans; D008944:Mitral Valve Insufficiency / Q000000981:diagnostic imaging* / Q000628:therapy; D017202:Myocardial Ischemia / Q000000981:diagnostic imaging* / Q000628:therapy; D011379:Prognosis; D018487:Ventricular Dysfunction, Left / Q000000981:diagnostic imaging; D020257:Ventricular Remodeling / Q000502:physiology