title: Compliance with inhaled corticosteroid treatment: rates reported by guardians and measured by the pharmacy.
abstract: OBJECTIVE
  There is elevated morbidity associated with asthma, particularly in developing countries, and failure to comply with inhaled corticosteroid treatment contributes to this morbidity. The objective of this study is to compare rates of compliance with beclomethasone treatment reported by parents or guardians with those measured by pharmacy dispensing records.
  
  
  METHODS
  A concurrent cohort study of 12 months' duration was carried out, enrolling 106 asthmatic children and adolescents, selected at random. Linear regression was used to compare rates of compliance reported by parents or guardians with the pharmacy dispensing records at the service, every 4 months after enrollment on the study.
  
  
  RESULTS
  Compliance rates reported by parents and/or guardians were always higher (p < 0.001) and exhibited a weak correlation with pharmacy records during the period studied; fourth (r = 0.37) and twelfth (r = 0.31) months of follow-up.
  
  
  CONCLUSIONS
  The rates of compliance reported by parents were overestimated during all study periods. The compliance rates of children with asthma should also be monitored by other methods and, in this case, pharmacy records effectively revealed compliance failures. Given its low cost, this method is indicated for verification of these compliance rates.
authors.affiliation: Disciplina de Pneumologia Pediátrica, Departamento de Pediatria, Faculdade de Medicina, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG, Brazil.
authors.forename: Laura M L B F
authors.initials: LM
authors.lastname: Lasmar
authors.forename: Paulo A M
authors.initials: PA
authors.lastname: Camargos
authors.forename: Leila F
authors.initials: LF
authors.lastname: Costa
authors.forename: Maria Teresa M
authors.initials: MT
authors.lastname: Fonseca
authors.forename: Maria Jussara F
authors.initials: MJ
authors.lastname: Fontes
authors.forename: Cassio C
authors.initials: CC
authors.lastname: Ibiapina
authors.forename: Cristina G
authors.initials: CG
authors.lastname: Alvim
authors.forename: José A R
authors.initials: JA
authors.lastname: Moura
authors.forename: Eugenio M A
authors.initials: EM
authors.lastname: Goulart
authors.forename: Emilia
authors.initials: E
authors.lastname: Sakurai
mesh_terms: D000280:Administration, Inhalation; D000293:Adolescent; D000328:Adult; D018927:Anti-Asthmatic Agents / Q000008:administration & dosage*; D001249:Asthma / Q000188:drug therapy*; D001507:Beclomethasone / Q000008:administration & dosage*; D002648:Child; D002675:Child, Preschool; D015331:Cohort Studies; D003157:Community Pharmacy Services; D005260:Female; D006801:Humans; D007872:Legal Guardians; D008297:Male; D009330:Nebulizers and Vaporizers; D010349:Patient Compliance / Q000706:statistics & numerical data*; D012720:Severity of Illness Index
chemical_list: D018927:Anti-Asthmatic Agents; D001507:Beclomethasone