title: Regioselective synthesis of asymmetrically substituted 2-quinoxalinol salen ligands.
abstract: Diamino-2-quinoxalinols are reacted with salicylaldehyde derivatives to produce 2-quinoxalinol imines regioselectively as one isomer in good yield. Regioselectivity has been determined through the use of isotopic 15N labeling experiments. The 2-quinoxalinol imines may then be reacted without further purification with additional salicylaldehyde derivatives to yield asymmetrically substituted 2-quinoxalinol salens.
authors.affiliation: Department of Chemistry and Biochemistry, College of Science and Mathematics, Auburn University, Auburn, AL 36849-5319, USA.
authors.forename: Xianghong
authors.initials: X
authors.lastname: Wu
authors.forename: Anne E V
authors.initials: AE
authors.lastname: Gorden
authors.forename: Stephen A
authors.initials: SA
authors.lastname: Tonks
authors.forename: Jonah Z
authors.initials: JZ
authors.lastname: Vilseck
mesh_terms: D020650:Combinatorial Chemistry Techniques; D005029:Ethylenediamines / Q000138:chemical synthesis* / Q000737:chemistry; D007097:Imines / Q000138:chemical synthesis / Q000737:chemistry; D008024:Ligands; D015394:Molecular Structure; D011810:Quinoxalines / Q000138:chemical synthesis / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D005029:Ethylenediamines; D007097:Imines; D008024:Ligands; D011810:Quinoxalines; C011452:disalicylaldehyde ethylenediamine