title: Changes in regulation of a transcription factor lead to autogamy in cultivated tomatoes.
abstract: We report the cloning of Style2.1, the major quantitative trait locus responsible for a key floral attribute (style length) associated with the evolution of self-pollination in cultivated tomatoes. The gene encodes a putative transcription factor that regulates cell elongation in developing styles. The transition from cross-pollination to self-pollination was accompanied, not by a change in the STYLE2.1 protein, but rather by a mutation in the Style2.1 promoter that results in a down-regulation of Style2.1 expression during flower development.
authors.affiliation: Department of Plant Breeding and Genetics, Cornell University, Ithaca, NY 14853, USA.
authors.forename: Kai-Yi
authors.initials: KY
authors.lastname: Chen
authors.forename: Bin
authors.initials: B
authors.lastname: Cong
authors.forename: Rod
authors.initials: R
authors.lastname: Wing
authors.forename: Julia
authors.initials: J
authors.lastname: Vrebalov
authors.forename: Steven D
authors.initials: SD
authors.lastname: Tanksley
mesh_terms: D000595:Amino Acid Sequence; D001483:Base Sequence; D005075:Biological Evolution; D002874:Chromosome Mapping; D003001:Cloning, Molecular; D003433:Crosses, Genetic; D015536:Down-Regulation; D035264:Flowers / Q000033:anatomy & histology* / Q000235:genetics / Q000254:growth & development; D017343:Genes, Plant; D005838:Genotype; D018257:Helix-Loop-Helix Motifs; D018551:Solanum lycopersicum / Q000033:anatomy & histology / Q000235:genetics* / Q000502:physiology*; D008969:Molecular Sequence Data; D010940:Plant Proteins / Q000737:chemistry / Q000235:genetics* / Q000378:metabolism; D011058:Pollen / Q000502:physiology; D011401:Promoter Regions, Genetic; D040641:Quantitative Trait Loci; D012098:Reproduction; D017384:Sequence Deletion; D014157:Transcription Factors / Q000737:chemistry / Q000235:genetics* / Q000378:metabolism; D014170:Transformation, Genetic
chemical_list: D010940:Plant Proteins; D014157:Transcription Factors