title: [Inversion of the sequence of surgery after neoadjuvant chemotherapy for synchronous liver metastases from colorectal cancer].
abstract: In some patients with colorectal cancer and synchronous liver metastases, chemotherapy and current combinations of chemotherapy allow the size of these metastases to be reduced so that they can be surgically resected. However, in many patients, the initial systematic treatment of the primary tumor is associated with growth of the metastases (which predict the patient's life expectancy). This metastatic growth contraindicates surgical treatment that might otherwise be curative. We report the case of a patient with advanced recto-colonic cancer, which responded well to chemotherapy given as neoadjuvant treatment prior to surgery, in which the hepatic metastases were resected before excision of the primary tumor.
authors.affiliation: Servicio de Cirugía General y Digestiva, Hospital de la Santa Creu i de Sant Pau, Barcelona, España. gmarin@hsp.santpau.es
authors.forename: Guillermo
authors.initials: G
authors.lastname: Marín-Hargreaves
authors.forename: Vicente
authors.initials: V
authors.lastname: Artigas
authors.forename: José A
authors.initials: JA
authors.lastname: González
authors.forename: Carmen
authors.initials: C
authors.lastname: Martínez
authors.forename: Eugenio
authors.initials: E
authors.lastname: Marcuello
authors.forename: Manuel
authors.initials: M
authors.lastname: Trías-Folch
mesh_terms: D017024:Chemotherapy, Adjuvant / Q000379:methods*; D015179:Colorectal Neoplasms / Q000188:drug therapy* / Q000473:pathology* / Q000601:surgery*; D003131:Combined Modality Therapy; D006801:Humans; D008113:Liver Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary* / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000000981:diagnostic imaging / Q000601:surgery; D013514:Surgical Procedures, Operative / Q000379:methods*; D013997:Time Factors; D014057:Tomography, X-Ray Computed