title: Cushing's syndrome in women with polycystic ovaries and hyperandrogenism.
abstract: BACKGROUND
  A 41-year-old woman presented to an endocrinology-gynecology clinic having been diagnosed 7 years earlier with polycystic ovarian syndrome on account of hirsutism, subfertility, greasy skin, acne and multiple ovarian cysts. Ovulation induction had led to a successful pregnancy. Subfertility recurred, however, and persisted alongside a new diagnosis of hypertension and progressive weight gain. Upon examination, the patient was hypertensive with facial plethora, rounded facies and violaceous abdominal striae.
  
  
  METHODS
  Low-dose dexamethasone test, bedtime salivary and 24-h urinary free cortisol estimations, CT scan of the abdomen, and serum hormone and gonadotropin analyses.
  
  
  METHODS
  Cushing's syndrome due to a right adrenocortical adenoma.
  
  
  RESULTS
  The patient underwent laparoscopic right adrenalectomy, which led to resolution of all symptoms, signs and biochemical abnormalities.
authors.affiliation: School of Medicine, University of Southampton, Duthie Building / Mailpoint 808, Southampton General Hospital, Tremona Road, Southampton SO16 6YD, UK.
authors.forename: P Gerry
authors.initials: PG
authors.lastname: Fegan
authors.forename: Derek D
authors.initials: DD
authors.lastname: Sandeman
authors.forename: Nils
authors.initials: N
authors.lastname: Krone
authors.forename: Deborah
authors.initials: D
authors.lastname: Bosman
authors.forename: Peter J
authors.initials: PJ
authors.lastname: Wood
authors.forename: Paul M
authors.initials: PM
authors.lastname: Stewart
authors.forename: Neil A
authors.initials: NA
authors.lastname: Hanley
mesh_terms: D000315:Adrenalectomy / Q000379:methods; D018246:Adrenocortical Adenoma / Q000150:complications / Q000175:diagnosis / Q000601:surgery; D000328:Adult; D003480:Cushing Syndrome / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D005260:Female; D006801:Humans; D017588:Hyperandrogenism / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D011085:Polycystic Ovary Syndrome / Q000150:complications / Q000175:diagnosis* / Q000601:surgery