Side effects of pharmacotherapy on bone with long-acting gonadorelin agonist triptorelin for paraphilia.
BACKGROUND
There have been limited research studies concerning the use of libido inhibitors for the treatment of patients with a paraphilia. Observational studies suggest that agents that lower testosterone are an effective treatment for paraphilia.


OBJECTIVE
We report a case of hormonal treatment of paraphilia that was associated with side effects.


METHODS
A 35-year-old man with a paraphilia was treated with long-acting gonadorelin.


RESULTS
The desired result was reduced preoccupation with sexuality, but there were various side effects including a serious amount of bone loss.


CONCLUSIONS
We believe that more attention should be given to the adverse effects of long-term treatment with triptorelin. In our view the drug regime needs to be revised.
Hoogeveen
John
J
Hoeve Boschoord, Boschoord Drenthe, The Netherlands. john.hoogeveen@ggzdrenthe.nl
Van der Veer
Eveline
E
D000328:Adult; D015519:Bone Density / Q000187:drug effects; D007987:Gonadotropin-Releasing Hormone / Q000819:agonists*; D006801:Humans; D008297:Male; D010024:Osteoporosis / Q000139:chemically induced; D010262:Paraphilic Disorders / Q000188:drug therapy*; D016896:Treatment Outcome; D017329:Triptorelin Pamoate / Q000008:administration & dosage* / Q000009:adverse effects
D017329:Triptorelin Pamoate; D007987:Gonadotropin-Releasing Hormone