title: [Sub-cutaneous closed-loop: continuous glucose measurement and external insulin pump: hope in treatment of type 1 diabetes].
abstract: The development of an artificial pancreas allowing a continuous insulin infusion according to glucose measurement is closed to be an ideal device for type 1 diabetic patients and for the diabetologits. The development of miniaturized external pumps infusing short acting analogues with pharmacokinetic profile closer to physiology, and the availability of accurate continuous glucose sensors has led to the development of closed-loop subcutaneous system. The feasibility of this solution as been proven at a small scale but remains to be confirmed in a home setting. Intermediate solutions, such as semi-automatic systems might be immediately valuable.
authors.affiliation: Service de Diabétologie-Maladies Métaboliques-Nutrition, Pôle Cardiovasculaire et Métabolique, Hôpital Rangueil, Centre Hospitalier Universitaire de Toulouse, av. Prof Jean Poulhes, 31403 Toulouse 9, France. puech.n@chu-toulouse.fr
authors.forename: N
authors.initials: N
authors.lastname: Puech-Bret
authors.forename: H
authors.initials: H
authors.lastname: Hanaire
mesh_terms: D001786:Blood Glucose / Q000032:analysis*; D003922:Diabetes Mellitus, Type 1 / Q000188:drug therapy*; D006801:Humans; D007332:Insulin Infusion Systems; D019397:Pancreas, Artificial
chemical_list: D001786:Blood Glucose