Wavelet transform for rabbit EEG with vagus nerve electric stimulation.
Vagus nerve electric stimulation is a new method for preventing and treating epilepsy, pain disorders and depression with a subcutaneous surgically implanted device. The mechanisms of action of implanted stimulation device are still unknown. And the vagus nerve electric stimulator has several operating and stimulation parameters with the programming wand or the magnet. We had finished designing a new vagus nerve electric stimulator for the epilepsy last year. In order to analysis and detect the effects on the brain characteristics with these operation and the electrical activation, the rabbits are implanted the device. Then the EEG is used for recording the brain functional activity of the rabbit with the stimulator. Moreover the wavelet transform is employed to classify and separate the EEG signals into different spectral components. The delta, theta, alpha and beta waves are obtained to better understand the stimulation effects on the brain. The results demonstrated that the new device is safe and has excellent potential role for the epilepsy treatment.
Chen
Zhaoyang
Z
Dept. of Eng. Mech., Tsinghua Univ., Beijing, PR China.
Hao
Hongwei
H
Li
Luming
L
Dong
Jie
J
D000465:Algorithms; D000818:Animals; D001921:Brain / Q000502:physiology*; D004558:Electric Stimulation / Q000379:methods*; D004569:Electroencephalography / Q000379:methods*; D008297:Male; D011817:Rabbits; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D012815:Signal Processing, Computer-Assisted; D014630:Vagus Nerve / Q000502:physiology*