title: The Molecule Pages database.
abstract: The UCSD-Nature Signaling Gateway Molecule Pages (http://www.signaling-gateway.org/molecule) provides essential information on more than 3800 mammalian proteins involved in cellular signaling. The Molecule Pages contain expert-authored and peer-reviewed information based on the published literature, complemented by regularly updated information derived from public data source references and sequence analysis. The expert-authored data includes both a full-text review about the molecule, with citations, and highly structured data for bioinformatics interrogation, including information on protein interactions and states, transitions between states and protein function. The expert-authored pages are anonymously peer reviewed by the Nature Publishing Group. The Molecule Pages data is present in an object-relational database format and is freely accessible to the authors, the reviewers and the public from a web browser that serves as a presentation layer. The Molecule Pages are supported by several applications that along with the database and the interfaces form a multi-tier architecture. The Molecule Pages and the Signaling Gateway are routinely accessed by a very large research community.
authors.affiliation: San Diego Supercomputer Center San Diego, La Jolla, CA 92093, Nature Publishing Group, 25 First Street, Cambridge, MA 02141, USA.
authors.forename: Brian
authors.initials: B
authors.lastname: Saunders
authors.forename: Stephen
authors.initials: S
authors.lastname: Lyon
authors.forename: Matthew
authors.initials: M
authors.lastname: Day
authors.forename: Brenda
authors.initials: B
authors.lastname: Riley
authors.forename: Emily
authors.initials: E
authors.lastname: Chenette
authors.forename: Shankar
authors.initials: S
authors.lastname: Subramaniam
authors.forename: Ilango
authors.initials: I
authors.lastname: Vadivelu
mesh_terms: D000818:Animals; D030562:Databases, Protein; D006801:Humans; D020407:Internet; D047908:Intracellular Signaling Peptides and Proteins / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D008322:Mammals / Q000378:metabolism; D051379:Mice; D015398:Signal Transduction; D014584:User-Computer Interface
chemical_list: D047908:Intracellular Signaling Peptides and Proteins