Effects of physiological parameters on the electrical properties of blood bank stored erythrocyte suspensions.
In this study, the physiological parameters such as extracellular (SAGM+CPD+residual plasma) Na+, K+, Cl-, pH, 2,3-DPG and ATP together with the Cole-Cole parameters were measured using erythrocyte suspensions from 51 male donors (31 donors form the training set and 20 donors are used for testing), on the 0th, 10th, 21st, 35th and 42nd days of storage. Accordingly, electrical parameters were all correlated with Na+, K+, Cl-, pH and ATP, at varying levels. By applying the multi-regression analysis, it is concluded that Ri, Re and Cm are appropriate for modeling Na+, K+, Cl-, pH and ATP during blood bank storage and predicting blood quality.
Sezdi
Mana
M
Bogazici University, Institute of Biomedical Engineering, Istanbul.
Ulgen
Yekta
Y
D000255:Adenosine Triphosphate / Q000737:chemistry; D001771:Blood Banks; D001790:Blood Physiological Phenomena; D001793:Blood Preservation / Q000295:instrumentation* / Q000379:methods; D017097:Electric Impedance; D004594:Electrophysiology; D004867:Equipment Design; D004905:Erythrocyte Aging; D004912:Erythrocytes / Q000378:metabolism*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008297:Male; D012044:Regression Analysis; D013048:Specimen Handling / Q000295:instrumentation* / Q000379:methods
D000255:Adenosine Triphosphate