Pharmacogenetic dose refinement prevents warfarin overdose in a patient who is highly warfarin-sensitive.
Grice
G R
GR
Milligan
P E
PE
Eby
C
C
Gage
B F
BF
D000368:Aged; D001189:Aryl Hydrocarbon Hydroxylases / Q000235:genetics; D062787:Drug Overdose / Q000517:prevention & control*; D005838:Genotype; D006801:Humans; D019934:International Normalized Ratio; D008297:Male; D006899:Mixed Function Oxygenases / Q000235:genetics; D010597:Pharmacogenetics / Q000379:methods*; D013250:Steroid Hydroxylases / Q000235:genetics; D064417:Vitamin K Epoxide Reductases; D014859:Warfarin / Q000008:administration & dosage*
D014859:Warfarin; D006899:Mixed Function Oxygenases; D013250:Steroid Hydroxylases; D001189:Aryl Hydrocarbon Hydroxylases; C029009:steroid hormone 7-alpha-hydroxylase; D064417:Vitamin K Epoxide Reductases