title: [Evaluation on the application of the mouse nicotine toxicity experiment in tobacco control among adolescents].
abstract: OBJECTIVE
  To explore the application of the mouse nicotine toxicity experiment in tobacco control among adolescents.
  
  
  METHODS
  A cross-sectional survey was conducted among 1626 students of three secondary schools with self-administered questionnaires three months after the intervention. The measurements of the student' s evaluation included their response, confidence and support to the experiment.
  
  
  RESULTS
  Among the respondents, 87.4% had interest in the experiment and 84.0% had perceived its impact. The mouse nicotine toxicity experiment was attracted by greater interest from the students and was strong perceived by impact on them, when compared with the multi-media and the textbook. There were statistically significant (P < 0.001) difference in students' response between the three interventions. And 85.5% of the students believed that nicotine could be similar effects on the human body and 83.7% thought that the experiment could educate middle school students refuse smoking. Among the students, 76.4% agreed to show this kind of animal experiments to middle school students but 9.4% objected. 843 (51.9%) students were willing to do the experiment by themselves. The grade 7 students had lower response and confidence to the experiment than grade 8 students (P < 0.05). The evaluation on the experiment were significant (P < 0.05) different among the students in three smoking stages: non-smokers more than irregular smokers more than regular smokers.
  
  
  CONCLUSIONS
  The mouse nicotine toxicity experiment was believed by most students and could get great support from them. It could deserve wider application in school-based tobacco control programs.
authors.affiliation: Department of Medical Statistics and Epidemiology, School of Public Health, Sun Yat-sen University, Guangzhou 510080, China.
authors.forename: Xiaozhong
authors.initials: X
authors.lastname: Wen
authors.forename: Weiqing
authors.initials: W
authors.lastname: Chen
authors.forename: Caihua
authors.initials: C
authors.lastname: Liang
authors.forename: Quan
authors.initials: Q
authors.lastname: Qiu
mesh_terms: D000293:Adolescent; D000294:Adolescent Behavior / Q000523:psychology*; D000818:Animals; D002648:Child; D002681:China; D003430:Cross-Sectional Studies; D005260:Female; D006266:Health Education / Q000379:methods*; D007722:Health Knowledge, Attitudes, Practice; D006293:Health Promotion; D006801:Humans; D008297:Male; D051379:Mice; D009538:Nicotine / Q000633:toxicity*; D000074606:Smoking Prevention; D013334:Students; D011795:Surveys and Questionnaires
chemical_list: D009538:Nicotine