Specific and sensitive detection of nucleic acids and RNases using gold nanoparticle-RNA-fluorescent dye conjugates.
Gold nanoparticles were modified with RNA and utilized to detect specific DNA sequences and various RNA nucleases.
Kim
Joong H
JH
Department of Chemistry and Biochemistry, University of California, Santa Barbara, California 93106, USA.
Estabrook
R August
RA
Braun
Gary
G
Lee
Briana R
BR
Reich
Norbert O
NO
D015374:Biosensing Techniques; D004277:DNA, Single-Stranded / Q000737:chemistry; D005456:Fluorescent Dyes / Q000737:chemistry; D006046:Gold / Q000737:chemistry*; D053758:Nanoparticles; D009696:Nucleic Acids / Q000032:analysis*; D012313:RNA / Q000737:chemistry*; D012260:Ribonucleases / Q000032:analysis*; D017422:Sequence Analysis, DNA / Q000379:methods
D004277:DNA, Single-Stranded; D005456:Fluorescent Dyes; D009696:Nucleic Acids; D012313:RNA; D006046:Gold; D012260:Ribonucleases