title: Is age relevant for the success of treatment of anisometropic amblyopia?
abstract: A prospective cohort study of 200 anisometropic amblyopes was conducted. The patients were classified into two groups. Group A: Patients less than 12 years of age. This consisted of 144 (72%) patients, the average age being 7.77 years (+/-2.34, range 1 to 12). Group B: Patients more than 12 years of age. This comprised 56 (28%) patients, the average age being 19.8 years (+/-5.47, range 12 to 30). Criterion for success was defined as best corrected visual acuity of 20/40 (0.5 logMAR equivalent) or better. The Chi-square test was used to compare baseline characteristics and success rates. There were no significant differences in the baseline characteristics between the two groups ( P =0.07). The treatment was successful in 108 (75%) in Group A and in 34 (60.7%) in Group B ( P = 0.07). There was no statistically significant change in the success rate of treatment of anisometropic amblyopia, even beyond 12 years of age.
authors.affiliation: Sion Eye Clinic and Microsurgery Centre, Mumbai, India. neelaanil@gmail.com
authors.forename: Neela A
authors.initials: NA
authors.lastname: Patwardhan
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000550:Amblyopia / Q000503:physiopathology / Q000628:therapy*; D002648:Child; D002675:Child, Preschool; D003519:Cyclopentolate / Q000008:administration & dosage*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D008297:Male; D009184:Mydriatics / Q000008:administration & dosage*; D009779:Occlusive Dressings; D009883:Ophthalmic Solutions; D011446:Prospective Studies; D012029:Refraction, Ocular; D012683:Sensory Deprivation; D016896:Treatment Outcome; D014792:Visual Acuity
chemical_list: D009184:Mydriatics; D009883:Ophthalmic Solutions; D003519:Cyclopentolate