[The influence of sex and age on the osteoprotegerin level in the blood].
The exploration and description of the new cytokine system of tumor necrosis factor (TNF) superfamily contributed to different look on the biology of the bone tissue cells. The OPG/RANKL/RANK system constitutes the important element of controlling the number of active osteoclasts by the osteoblasts. It is essential to determine the influence of age and dependence among osteoprotegerin (OPG) and the level of sex hormones, biochemical markers of bone turnover and other factors in the metabolism of bone tissue in the state of physiology and pathophysiology.
Sobańska
Izabela
I
Katedry i Zakładu Diagnostyki Laboratoryjnej Collegium Medicum im. Ludwika Rydygiera w Bydgoszczy, Uniwersytetu Mikołaja Kopernika w Toruniu. kizdiagn@cm.umk.pl
Odrowaz-Sypniewska
Grazyna
G
Kuligowska
Magdalena
M
D000367:Age Factors; D015415:Biomarkers / Q000097:blood; D001862:Bone Resorption / Q000097:blood; D005260:Female; D012739:Gonadal Steroid Hormones / Q000097:blood; D006801:Humans; D008297:Male; D053858:Metabolic Networks and Pathways; D010006:Osteoblasts / Q000166:cytology / Q000378:metabolism; D010010:Osteoclasts / Q000166:cytology / Q000378:metabolism; D053244:Osteoprotegerin / Q000097:blood*; D011485:Protein Binding; D053245:RANK Ligand / Q000097:blood; D053246:Receptor Activator of Nuclear Factor-kappa B / Q000097:blood; D012016:Reference Values; D012737:Sex Factors; D015398:Signal Transduction
D015415:Biomarkers; D012739:Gonadal Steroid Hormones; D053244:Osteoprotegerin; D053245:RANK Ligand; D053246:Receptor Activator of Nuclear Factor-kappa B