Tourette's syndrome is not associated with interleukin-10 receptor 1 variants on chromosome 11q23.3.
Interleukin-10 receptor 1 (IL-10R1) single nucleotide polymorphisms, located on chromosome 11q23 - a strong candidate for linkage with Tourette's syndrome (TS) - have been investigated for association with TS. DNA of 77 patients with a DSM-IV (Diagnostic and Statistical Manual IV) diagnosis of TS and 250 healthy controls was genotyped. IL-10R1 was not associated with TS.
Kindler
Jochen
J
Department of Biological Psychiatry, University Hospital of Psychiatry and Psychotherapy, Medical University of Vienna, Austria. jochen.kindler@gef.be.ch
Schosser
Alexandra
A
Stamenkovic
Mara
M
Schloegelhofer
Monika
M
Leisch
Friedrich
F
Hornik
Kurt
K
Aschauer
Harald
H
Gasche
Christoph
C
D000328:Adult; D000483:Alleles; D001323:Autoantibodies / Q000276:immunology; D002880:Chromosomes, Human, Pair 11 / Q000235:genetics*; D005260:Female; D005838:Genotype; D006801:Humans; D053709:Interleukin-10 Receptor alpha Subunit / Q000235:genetics* / Q000276:immunology; D008297:Male; D016133:Polymerase Chain Reaction; D005879:Tourette Syndrome / Q000235:genetics* / Q000276:immunology
D001323:Autoantibodies; D053709:Interleukin-10 Receptor alpha Subunit