title: Electrochemical behavior of uric acid and epinephrine at an electrochemically activated glassy carbon electrode.
abstract: A pretreated glassy carbon electrode by electrochemical activation has been proposed for simultaneous investigation and determination of epinephrine and uric acid by differential pulse voltammetry. This pretreated glassy carbon electrode exhibits a potent and persistent electron-mediating behavior followed by well-separated oxidation peaks towards epinephrine and uric acid with a potential difference of 161 mV, which is large enough to determine epinephrine and uric acid individually and simultaneously. Under the optimum condition, the detection limit of epinephrine is 8.9 x 10(-8)mol L(-1) and that of uric acid is 1.6 x 10(-7)mol L(-1). The proposed method was successfully used for the determination of epinephrine and uric acid in real samples with satisfactory results.
authors.affiliation: School of Chemistry and Chemical Engineering, Southwest University, Chongqing, PR China.
authors.forename: Jian Xian
authors.initials: JX
authors.lastname: Qiao
authors.forename: Hong Qun
authors.initials: HQ
authors.lastname: Luo
authors.forename: Nian Bing
authors.initials: NB
authors.lastname: Li
mesh_terms: D004563:Electrochemistry; D004566:Electrodes; D004837:Epinephrine / Q000737:chemistry*; D006863:Hydrogen-Ion Concentration; D015203:Reproducibility of Results; D014527:Uric Acid / Q000737:chemistry*
chemical_list: D014527:Uric Acid; D004837:Epinephrine