title: Laparoscopic colorectal surgery is safe in the high-risk patient: a NSQIP risk-adjusted analysis.
abstract: BACKGROUND
  Laparoscopic colectomy was considered initially to be contraindicated in patients at high risk for operative morbidity and mortality. We hypothesized that this procedure is safe to perform in high-risk patients, stratifying this risk using National VA Surgical Quality Improvement Program (NSQIP) algorithms.
  
  
  METHODS
  A case-matched, comparative study was performed for high-risk veteran patients who underwent colectomy during the period October 2002-September 2004. Consecutive patients undergoing laparoscopic colectomy were matched to patients who underwent open colectomy during the same period for age, body mass index (BMI), procedure, and NSQIP-predicted risk. The groups were compared for risk-stratified, 30-day morbidity/mortality, length of stay (LOS), and operating time.
  
  
  RESULTS
  Forty-five patients (23 laparoscopic and 22 open cases) were defined as at high risk for complications (predicted complication >0.15). The rate of major complications was significantly less in the laparoscopic group. There were 4 (18%) cases of postoperative respiratory failure in the open group and none in the laparoscopic group. There was no surgically related mortality in the laparoscopic group, compared with 2 deaths in the open group (P = .5). Median LOS was less in the laparoscopic group (5 days) compared with open (8 days) (P = .001). There were no significant differences in operating time or the number of minor complications.
  
  
  CONCLUSIONS
  Our results suggest that the laparoscopic approach to colorectal diseases is safe in the population of patients at high risk for operative morbidity and mortality. Rather, this approach may represent a safer alternative to open access.
authors.affiliation: Department of Surgery, VA Pittsburgh Healthcare System and the University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA.
authors.forename: Carol A
authors.initials: CA
authors.lastname: McCloskey
authors.forename: Mark A
authors.initials: MA
authors.lastname: Wilson
authors.forename: Steven J
authors.initials: SJ
authors.lastname: Hughes
authors.forename: George M
authors.initials: GM
authors.lastname: Eid
mesh_terms: D000236:Adenoma / Q000453:epidemiology* / Q000601:surgery*; D000368:Aged; D000465:Algorithms; D015331:Cohort Studies; D003082:Colectomy / Q000706:statistics & numerical data*; D015179:Colorectal Neoplasms / Q000453:epidemiology* / Q000601:surgery*; D015897:Comorbidity; D016208:Databases, Factual / Q000706:statistics & numerical data; D006801:Humans; D010535:Laparoscopy / Q000706:statistics & numerical data*; D008297:Male; D011183:Postoperative Complications / Q000453:epidemiology; D012189:Retrospective Studies; D020379:Risk Adjustment; D012307:Risk Factors