title: [Destination therapy in end-stage heart failure. A possible alternative to heart transplantation?].
abstract: The incidence of heart failure continues to increase but the number of available heart donors is limited. Implantation of circulatory assist devices as a permanent alternative to heart transplantation has become a promising new alternative in patients not eligible for heart transplantation (destination therapy). New technical advances have increased the durability of the devices and reduced complications.New generations of rotator pumps are smaller and more durable and will expand the use of these devices for destination therapy. This review discusses the current state of knowledge and indications for destination therapy in end-stage heart failure.
authors.affiliation: Rigshospitalet, Hjertecentret, Thoraxkirurgisk Klinisk, København Ø.psolsen@rh.dk
authors.forename: Peter Skov
authors.initials: PS
authors.lastname: Olsen
authors.forename: Kåre
authors.initials: K
authors.lastname: Sander
authors.forename: Peter Bo
authors.initials: PB
authors.lastname: Hansen
authors.forename: Svend Aage
authors.initials: SA
authors.lastname: Mortensen
authors.forename: Finn
authors.initials: F
authors.lastname: Gustafsson
authors.forename: Søren
authors.initials: S
authors.lastname: Boesgaard
mesh_terms: D006333:Heart Failure / Q000401:mortality / Q000601:surgery*; D016027:Heart Transplantation; D006353:Heart-Assist Devices; D006801:Humans; D016032:Randomized Controlled Trials as Topic; D016896:Treatment Outcome