title: Bone tumors in a population of 400 000 insured Swedish dogs up to 10 y of age: incidence and survival.
abstract: The objectives of this study were to describe the incidence of, survival until, and survival after the diagnosis of canine bone tumors by breed, sex, age, and geographic location of residence. Dogs under 10 y old and insured by a Swedish insurance company between 1995 and 2002 were studied. In total, 764 dogs had claims for bone tumors, and the incidence rate was 5.5 cases per 10 000 dog-years at risk (DYAR). At ages 6, 8, and 10 y, the proportions of dogs with bone tumors were 0.13%, 0.30%, and 0.64%. The top 3 breeds at risk were Irish wolfhound, St. Bernard, and leonberger (incidence rates 99, 78, and 53 cases per 10 000 DYAR, respectively). Median survival time after diagnosis was 56 d in the 419 dogs that survived > or = 1 d. With a Cox regression model controlling for breed and age, females were shown to be at decreased risk of bone tumors, with a hazard ratio of 0.71 (99% confidence interval 0.58 to 0.87).
authors.affiliation: Department of Clinical Sciences, Faculty of Veterinary Medicine and Animal Science, Swedish University of Agricultural Sciences, SE-750 07 Uppsala, Sweden. Agneta.Egenvall@kv.slu.se
authors.forename: Agneta
authors.initials: A
authors.lastname: Egenvall
authors.forename: Ane
authors.initials: A
authors.lastname: Nødtvedt
authors.forename: Henrik
authors.initials: H
authors.lastname: von Euler
mesh_terms: D000367:Age Factors; D000818:Animals; D001859:Bone Neoplasms / Q000453:epidemiology / Q000401:mortality / Q000662:veterinary*; D001947:Breeding; D004283:Dog Diseases / Q000453:epidemiology* / Q000401:mortality*; D004285:Dogs; D005260:Female; D015994:Incidence; D007341:Insurance / Q000706:statistics & numerical data*; D008297:Male; D011379:Prognosis; D016016:Proportional Hazards Models; D012737:Sex Factors; D016019:Survival Analysis; D013548:Sweden / Q000453:epidemiology