title: Longitudinal relationship between root caries and serum albumin.
abstract: Serum albumin levels are a practical marker of general health status in the elderly and have been used to determine the severity of an underlying disease and the risk for death. This longitudinal study evaluated the relationship between serum albumin levels and root caries. A total of 266 persons with at least 1 tooth at baseline underwent a baseline examination and then annual investigations for 6 years. Multiple linear regression analysis was used to assess the relationship between changes in serum albumin levels and the number of root caries lesions over 6 years, after adjustment for confounding factors. Change in the number of root caries lesions was significantly associated with change in serum albumin concentrations. The standardized coefficient was -0.148 (p = 0.024). We can confirm that serum albumin concentration correlates with root caries events. From these data, we conclude that persons with hypoalbuminemia are at high risk for root caries.
authors.affiliation: Division of Preventive Dentistry, Department of Oral Health Science, Graduate School of Medical and Dental Sciences, Niigata University, 2-5274 Gakkocho-Dori, Niigata, 951-8514, Japan. akihiro@dent.niigata-u.ac.jp
authors.forename: A
authors.initials: A
authors.lastname: Yoshihara
authors.forename: N
authors.initials: N
authors.lastname: Takano
authors.forename: T
authors.initials: T
authors.lastname: Hirotomi
authors.forename: H
authors.initials: H
authors.lastname: Ogawa
authors.forename: N
authors.initials: N
authors.lastname: Hanada
authors.forename: H
authors.initials: H
authors.lastname: Miyazaki
mesh_terms: D000368:Aged; D000704:Analysis of Variance; D015992:Body Mass Index; D005260:Female; D015577:Geriatric Assessment; D006801:Humans; D034141:Hypoalbuminemia / Q000209:etiology; D007074:Immunoglobulin G / Q000097:blood; D016014:Linear Models; D008137:Longitudinal Studies; D008297:Male; D017622:Periodontal Attachment Loss / Q000097:blood / Q000150:complications; D017213:Root Caries / Q000097:blood* / Q000150:complications; D012709:Serum Albumin / Q000032:analysis*; D018709:Statistics, Nonparametric
chemical_list: D007074:Immunoglobulin G; D012709:Serum Albumin