title: In vitro antimycoplasmal activity of six Jordanian medicinal plants against three Mycoplasma species.
abstract: The in vitro effect of six Jordanian traditional medicine plant methanolic extracts were tested against 32 isolates of Mycoplasma species; Mycoplasma mycoides subsp. mycoides LC (6), Mycoplasma capricolum subsp. capricolum (8) and M. putrefaciens (18), all isolated from either nasal swabs or milk, from sheep and goats in different regions in Jordan. All Mycoplasma species showed susceptibility to Artemisia herba-alba and Artemisia arborescens with MIC ranges from 3.125-12.5 mg/ml. Allium sativum and Punica grantum showed limited activity against some Mycoplasma isolates. Olea europea and Citrullus colocynthis showed no in vitro activity against any of the Mycoplasma species tested. Artemisia herba-alba and Artemisia arborescens may therefore be useful for the treatment of mycoplasma infections.
authors.affiliation: Department of Biological Sciences and Chemistry, Section of Biotechnology and Genetic Engineering, University of Nizwa, Birkat Almouze, Oman.
authors.forename: W
authors.initials: W
authors.lastname: Al-Momani
authors.forename: E
authors.initials: E
authors.lastname: Abu-Basha
authors.forename: S
authors.initials: S
authors.lastname: Janakat
authors.forename: R A J
authors.initials: RA
authors.lastname: Nicholas
authors.forename: R D
authors.initials: RD
authors.lastname: Ayling
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D015169:Colony Count, Microbial / Q000662:veterinary; D004305:Dose-Response Relationship, Drug; D015511:Goat Diseases / Q000188:drug therapy* / Q000382:microbiology; D006041:Goats; D008826:Microbial Sensitivity Tests / Q000662:veterinary; D009174:Mycoplasma / Q000187:drug effects*; D009175:Mycoplasma Infections / Q000188:drug therapy / Q000382:microbiology / Q000662:veterinary*; D010936:Plant Extracts / Q000494:pharmacology*; D010946:Plants, Medicinal / Q000737:chemistry*; D012756:Sheep; D012757:Sheep Diseases / Q000188:drug therapy* / Q000382:microbiology; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents; D010936:Plant Extracts