title: A simple synthetic route to methyl 3-fluoropyridine-4-carboxylate by nucleophilic aromatic substitution.
abstract: The nitro group of methyl 3-nitropyridine-4-carboxylate (1) has successfully been replaced by fluoride anion via nucleophilic aromatic substitution to give the 3-fluoro- pyridine-4-carboxylate 2.
authors.affiliation: Department of Chemistry, Norwegian University of Science and Technology, NTNU N-7491 Trondheim, Norway. tjosas@chem.ntnu.no
authors.forename: Freddy
authors.initials: F
authors.lastname: Tjosaas
authors.forename: Anne
authors.initials: A
authors.lastname: Fiksdahl
mesh_terms: D002264:Carboxylic Acids / Q000138:chemical synthesis* / Q000737:chemistry; D007539:Isonicotinic Acids / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D011725:Pyridines / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D002264:Carboxylic Acids; D007539:Isonicotinic Acids; D011725:Pyridines; C525262:methyl 3-fluoropyridine-4-carboxylate