title: Treatment of port-wine stains with the 595-nm pulsed dye laser: a pilot study in Chinese patients.
abstract: The 595-nm pulsed dye laser (PDL) is one of the newest developments in the treatment for port-wine stains (PWS). The aim of this study was to investigate the effectiveness of the treatment of PWS in Chinese patients using the 595-nm PDL. In total, 184 patients with PWS over the face, neck and trunk or limbs were enrolled in the study. All the patients were treated with the 595-nm PDL 3-6 times, with a 4-week interval between each treatment. Treatment parameters varied for each patient according to the colour and location of the PWS. The efficacy of treatments and any side-effects were evaluated. Results were graded as percentage resolution (0-25%, 25-50%, 50-75% and 75-100%). Of the 184 patients who completed the study, 115 (62.5%) achieved excellent improvement, 38 (20.7%) achieved good results, and 31 (16.8%) had an unsatisfactory outcome (moderate and poor response). We found > 75% improvement for 76% of facial PWS (95/125), 43% of neck PWS and 20.8% of trunk or limb PWS. Pain and topical erythema were commonly reported immediately after the laser treatments. Prominent hyperpigmentation occurred in only 11 cases (6.0%) with poor improvement, and resolved within 6 months. The 595-nm PDL appears to be safe, effective and well tolerated in the treatment of PWS in Chinese patients.
authors.affiliation: Institute of Laser Medicine and Bio-Photonics, Shanghai Jiao Tong University, Shanghai, China.
authors.forename: H
authors.initials: H
authors.lastname: Liu
authors.forename: Y
authors.initials: Y
authors.lastname: Dang
authors.forename: X
authors.initials: X
authors.lastname: Chai
authors.forename: Z
authors.initials: Z
authors.lastname: Wang
authors.forename: L
authors.initials: L
authors.lastname: Ma
authors.forename: Q
authors.initials: Q
authors.lastname: Ren
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D004890:Erythema / Q000209:etiology; D005148:Facial Dermatoses / Q000473:pathology / Q000601:surgery; D005260:Female; D006801:Humans; D007223:Infant; D053685:Laser Therapy / Q000009:adverse effects / Q000379:methods*; D008297:Male; D010146:Pain / Q000209:etiology; D010865:Pilot Projects; D019339:Port-Wine Stain / Q000473:pathology / Q000601:surgery*; D012189:Retrospective Studies; D016896:Treatment Outcome