title: Mycobacterium bovis BCG vertebral osteomyelitis after intravesical BCG therapy, diagnosed by PCR-based genomic deletion analysis.
abstract: We report a case of Mycobacterium bovis BCG vertebral osteomyelitis 1.8 years after intravesical BCG therapy for bladder cancer. We differentiated BCG from other Mycobacterium tuberculosis complex members by PCR analysis of deletion regions and started an appropriate chemotherapy regimen resulting in the remission of symptoms within 1 month.
authors.affiliation: Department of Orthopedics, Fukushima Medical University, Fukushima, Japan.
authors.forename: Takuya
authors.initials: T
authors.lastname: Nikaido
authors.forename: Kei
authors.initials: K
authors.lastname: Ishibashi
authors.forename: Koji
authors.initials: K
authors.lastname: Otani
authors.forename: Shoji
authors.initials: S
authors.lastname: Yabuki
authors.forename: Shinichi
authors.initials: S
authors.lastname: Konno
authors.forename: Shuichi
authors.initials: S
authors.lastname: Mori
authors.forename: Kazutaka
authors.initials: K
authors.lastname: Ohashi
authors.forename: Takashi
authors.initials: T
authors.lastname: Ishida
authors.forename: Michiko
authors.initials: M
authors.lastname: Nakano
authors.forename: Osamu
authors.initials: O
authors.lastname: Yamaguchi
authors.forename: Tatsuo
authors.initials: T
authors.lastname: Suzutani
authors.forename: Shinichi
authors.initials: S
authors.lastname: Kikuchi
mesh_terms: D000369:Aged, 80 and over; D000995:Antitubercular Agents / Q000627:therapeutic use; D004269:DNA, Bacterial / Q000235:genetics; D006801:Humans; D008159:Lumbar Vertebrae / Q000000981:diagnostic imaging / Q000473:pathology; D008297:Male; D009163:Mycobacterium bovis / Q000302:isolation & purification*; D010019:Osteomyelitis / Q000188:drug therapy / Q000382:microbiology*; D016133:Polymerase Chain Reaction / Q000379:methods; D011859:Radiography; D014376:Tuberculosis / Q000150:complications* / Q000188:drug therapy / Q000382:microbiology*
chemical_list: D000995:Antitubercular Agents; D004269:DNA, Bacterial