title: Discovery of recurrent multiple brain states in non-convulsive status epilepticus.
abstract: OBJECTIVE
  We study burst-like patterns of epileptiform discharges in non-convulsive status epilepticus (SE).
  
  
  METHODS
  Epileptiform burst-like transients were identified by estimating the amplitude envelope of the EEG signal, and recurrence and similarities were identified by pairwise matching in the time-domain.
  
  
  RESULTS
  We identified similarities in the onset of a significant fraction of the epileptiform bursts, and a bimodal distribution of the burst durations.
  
  
  CONCLUSIONS
  Bursts of epileptiform discharges during a non-convulsive SE are manifestations of multiple patterns of recurring brain states.
  
  
  CONCLUSIONS
  Quantitative description of ictal phenomena in epilepsy and status epilepticus adds to the knowledge of abnormal brain behavior and may assist in improved patient care.
authors.affiliation: Department of Neurology and Clinical Neurophysiology, Medisch Spectrum Twente, 7500 KA, Enschede, The Netherlands. m.vanputten@mailcss.com
authors.forename: Michel J A M
authors.initials: MJ
authors.lastname: van Putten
authors.forename: Maurice H P M
authors.initials: MH
authors.lastname: van Putten
mesh_terms: D000465:Algorithms; D001931:Brain Mapping / Q000379:methods; D002540:Cerebral Cortex / Q000503:physiopathology; D004568:Electrodiagnosis / Q000379:methods*; D004569:Electroencephalography / Q000379:methods; D004827:Epilepsy / Q000175:diagnosis* / Q000503:physiopathology*; D005071:Evoked Potentials; D005260:Female; D006801:Humans; D008875:Middle Aged; D009415:Nerve Net / Q000503:physiopathology; D011237:Predictive Value of Tests; D012815:Signal Processing, Computer-Assisted; D013226:Status Epilepticus / Q000175:diagnosis* / Q000503:physiopathology*