title: [Genetic basis of time perception in athletes].
abstract: The association between the subjective time perception and polymorphism of some genes, regulating activity of serotonin and dopamine, was studied in 89 synchronized swimmers. COMT gene, responsible for dopamine destruction, influences on reproduction of short time intervals (1-2 s). 5-HT2A and MAOA genes, regulating activity of serotonin, influence on subjective time flow. 5-HTT and COMT genes, regulating activity of serotonin and dopamine respectively, are related with accuracy of orientation in time. Association of time perception with different genes and mediators suggests different perception mechanisms, in different time ranges, in concordance with the previous physiological studies. The current study reveals that these physiological mechanisms have different molecular-neurochemical basis that helps to overcome the gap between the investigation on systemic and molecular levels.
authors.forename: G V
authors.initials: GV
authors.lastname: Portnova
authors.forename: O V
authors.initials: OV
authors.lastname: Sysoeva
authors.forename: N V
authors.initials: NV
authors.lastname: Maliuchenko
authors.forename: M A
authors.initials: MA
authors.lastname: Timofeeva
authors.forename: M A
authors.initials: MA
authors.lastname: Kulikova
authors.forename: A G
authors.initials: AG
authors.lastname: Tonevitskiĭ
authors.forename: M P
authors.initials: MP
authors.lastname: Kirpichnikov
authors.forename: A M
authors.initials: AM
authors.lastname: Ivanitskiĭ
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002394:Catechol O-Methyltransferase / Q000235:genetics*; D002648:Child; D004298:Dopamine / Q000378:metabolism; D005260:Female; D006801:Humans; D008875:Middle Aged; D008995:Monoamine Oxidase / Q000235:genetics*; D011110:Polymorphism, Genetic; D044402:Receptor, Serotonin, 5-HT2A / Q000235:genetics*; D012701:Serotonin / Q000378:metabolism; D050486:Serotonin Plasma Membrane Transport Proteins / Q000235:genetics*; D013550:Swimming; D013998:Time Perception
chemical_list: D044402:Receptor, Serotonin, 5-HT2A; C493230:SLC6A4 protein, human; D050486:Serotonin Plasma Membrane Transport Proteins; D012701:Serotonin; D008995:Monoamine Oxidase; D002394:Catechol O-Methyltransferase; D004298:Dopamine