Avian influenza (H5N1) susceptibility and receptors in dogs.
Inoculation of influenza (H5N1) into beagles resulted in virus excretion and rapid seroconversion with no disease. Binding studies that used labeled influenza (H5N1) showed virus attachment to higher and lower respiratory tract tissues. Thus, dogs that are subclinically infected with influenza (H5N1) may contribute to virus spread.
Maas
Riks
R
Wageningen University and Research Centre, Lelystad, The Netherlands. riks.maas@wur.nl
Tacken
Mirriam
M
Ruuls
Lisette
L
Koch
Guus
G
van Rooij
Eugene
E
Stockhofe-Zurwieden
Norbert
N
D000818:Animals; D000914:Antibodies, Viral / Q000097:blood; D001717:Birds; D004196:Disease Outbreaks / Q000517:prevention & control; D004198:Disease Susceptibility; D004285:Dogs; D053124:Influenza A Virus, H5N1 Subtype / Q000254:growth & development / Q000378:metabolism* / Q000472:pathogenicity; D005585:Influenza in Birds / Q000276:immunology / Q000378:metabolism / Q000821:virology*; D011991:Receptors, Virus / Q000378:metabolism*; D012137:Respiratory System / Q000378:metabolism / Q000821:virology; D053585:Virus Attachment; D017201:Virus Shedding
D000914:Antibodies, Viral; D011991:Receptors, Virus