title: Loss of exploratory vertical saccades after unilateral frontal eye field damage.
abstract: Despite their relevance for locomotion and social interaction in everyday situations, little is known about the cortical control of vertical saccades in humans. Results from microstimulation studies indicate that both frontal eye fields (FEFs) contribute to these eye movements. Here, we present a patient with a damaged right FEF, who hardly made vertical saccades during visual exploration. This finding suggests that, for the cortical control of exploratory vertical saccades, integrity of both FEFs is indeed important.
authors.affiliation: Perception & Eye Movement Laboratory, Department of Neurology, University Hospital, 3010 Bern, Switzerland.
authors.forename: T
authors.initials: T
authors.lastname: Pflugshaupt
authors.forename: T
authors.initials: T
authors.lastname: Nyffeler
authors.forename: R
authors.initials: R
authors.lastname: von Wartburg
authors.forename: C W
authors.initials: CW
authors.lastname: Hess
authors.forename: R M
authors.initials: RM
authors.lastname: Müri
mesh_terms: D001288:Attention / Q000502:physiology; D001927:Brain Diseases / Q000175:diagnosis / Q000503:physiopathology*; D004292:Dominance, Cerebral / Q000502:physiology*; D004585:Electrooculography; D005260:Female; D005500:Follow-Up Studies; D005625:Frontal Lobe / Q000503:physiopathology*; D006801:Humans; D008875:Middle Aged; D009460:Neurologic Examination; D015840:Oculomotor Nerve Diseases / Q000175:diagnosis / Q000503:physiopathology; D009949:Orientation / Q000502:physiology*; D010364:Pattern Recognition, Visual / Q000502:physiology*; D010468:Perceptual Disorders / Q000175:diagnosis / Q000503:physiopathology*; D011597:Psychomotor Performance / Q000502:physiology; D011698:Pursuit, Smooth / Q000502:physiology; D012075:Remission, Spontaneous; D012438:Saccades / Q000502:physiology*; D012815:Signal Processing, Computer-Assisted; D014057:Tomography, X-Ray Computed; D014794:Visual Fields / Q000502:physiology*