title: Micro-gas analysis system for measurement of nitric oxide and nitrogen dioxide: respiratory treatment and environmental mobile monitoring.
abstract: In this paper, novel microsystems for gas analysis and gas generation are described. The same microchannel devices covered with a gas permeable membrane were used for both the gas collection and the gas generation. For the first time, a dual liquid flow system was utilized in a micro-gas analysis system. Even though micropumps are utilized in the dual line microsystem, a good baseline was obtained in the NO2 measurement with Griess-Saltzman chemistry. The system was developed for on-site measurements in medical treatment; the treatment is of respiratory disease syndrome by NO inhalation and the monitoring is of the product NO and the harmful byproduct NO2. The system was also applied to mobile atmospheric monitoring. Chemical NO generation using the microchannel device was investigated for safe NO inhalation as an alternative to a NO generator based on pulsed arc discharge.
authors.affiliation: Department of Chemistry, Graduate School of Science and Technology, Kumamoto University, 2-39-1 Kurokami, Kumamoto 860-8555, Japan. todakei@sci.kumamoto-u.ac.jp
authors.forename: Kei
authors.initials: K
authors.lastname: Toda
authors.forename: Yuki
authors.initials: Y
authors.lastname: Hato
authors.forename: Shin-ichi
authors.initials: S
authors.lastname: Ohira
authors.forename: Takao
authors.initials: T
authors.lastname: Namihira
mesh_terms: D000388:Air / Q000032:analysis / Q000592:standards; D004784:Environmental Monitoring / Q000379:methods*; D056656:Lab-On-A-Chip Devices; D046208:Microchip Analytical Procedures / Q000379:methods; D009569:Nitric Oxide / Q000032:analysis*; D009585:Nitrogen Dioxide / Q000032:analysis*; D012138:Respiratory Therapy / Q000941:ethics / Q000295:instrumentation / Q000379:methods / Q000592:standards
chemical_list: D009569:Nitric Oxide; D009585:Nitrogen Dioxide