Mussel-inspired surface chemistry for multifunctional coatings.
We report a method to form multifunctional polymer coatings through simple dip-coating of objects in an aqueous solution of dopamine. Inspired by the composition of adhesive proteins in mussels, we used dopamine self-polymerization to form thin, surface-adherent polydopamine films onto a wide range of inorganic and organic materials, including noble metals, oxides, polymers, semiconductors, and ceramics. Secondary reactions can be used to create a variety of ad-layers, including self-assembled monolayers through deposition of long-chain molecular building blocks, metal films by electroless metallization, and bioinert and bioactive surfaces via grafting of macromolecules.
Lee
Haeshin
H
Biomedical Engineering, Northwestern University, 2145 Sheridan Road, Evanston, IL 60208, USA.
Dellatore
Shara M
SM
Miller
William M
WM
Messersmith
Phillip B
PB
D000268:Adhesiveness; D000818:Animals; D001704:Biopolymers / Q000737:chemistry; D002448:Cell Adhesion; D015815:Cell Adhesion Molecules / Q000737:chemistry; D002460:Cell Line; D002516:Ceramics / Q000737:chemistry; D004295:Dihydroxyphenylalanine / Q000737:chemistry; D004298:Dopamine / Q000737:chemistry*; D005347:Fibroblasts / Q000502:physiology; D006801:Humans; D006820:Hyaluronic Acid / Q000737:chemistry; D006863:Hydrogen-Ion Concentration; D008670:Metals / Q000737:chemistry; D049880:Mytilus edulis / Q000737:chemistry / Q000502:physiology; D010084:Oxidation-Reduction; D010087:Oxides / Q000737:chemistry; D011108:Polymers / Q000737:chemistry*; D011506:Proteins / Q000737:chemistry; D012666:Semiconductors; D013499:Surface Properties
D001704:Biopolymers; D015815:Cell Adhesion Molecules; D008670:Metals; D010087:Oxides; D011108:Polymers; D011506:Proteins; D004295:Dihydroxyphenylalanine; D006820:Hyaluronic Acid; D004298:Dopamine