Dynamical analysis of uterine cell electrical activity model.
The uterus is a physiological system consisting of a large number of interacting smooth muscle cells. The uterine excitability changes remarkably with time, generally quiescent during pregnancy, the uterus exhibits forceful synchronized contractions at term leading to fetus expulsion. These changes characterize thus a dynamical system susceptible of being studied through formal mathematical tools. Multiple physiological factors are involved in the regulation process of this complex system. Our aim is to relate the physiological factors to the uterine cell dynamic behaviors. Taking into account a previous work presented, in which the electrical activity of a uterine cell is described by a set of ordinary differential equations, we analyze the impact of physiological parameters on the response of the model, and identify the main subsystems generating the complex uterine electrical activity, with respect to physiological data.
Rihana
S
S
Biomecanique & Genie Biomed., Univ. de Technol. de Compiegne.
Santos
J
J
Mondie
S
S
Marque
C
C
D000818:Animals; D002118:Calcium / Q000502:physiology; D004594:Electrophysiology; D005260:Female; D006706:Homeostasis; D008954:Models, Biological; D012964:Sodium / Q000502:physiology; D014599:Uterus / Q000166:cytology* / Q000502:physiology*
D012964:Sodium; D002118:Calcium