title: Towards new tuberculosis drugs.
abstract: The need for better drugs to treat tuberculosis has never been greater. Despite insufficient funding for discovery research, intensive efforts have been made to find and develop new lead compounds capable of reducing the duration of the present treatment known as DOTS (directly observed therapy short course), from 6 to under 4 months. This minireview describes the progress achieved during the last 5 years and highlights some of the successes without neglecting the problems.
authors.affiliation: Global Health Institute, Ecole Polytechnique Fédérale de Lausanne, AI 3151, Station 15, CH-1015 Lausanne, Switzerland. stewart.cole@epfl.ch
authors.forename: S T
authors.initials: ST
authors.lastname: Cole
authors.forename: P M
authors.initials: PM
authors.lastname: Alzari
mesh_terms: D000995:Antitubercular Agents / Q000737:chemistry / Q000145:classification / Q000627:therapeutic use*; D015195:Drug Design; D006801:Humans; D014376:Tuberculosis / Q000188:drug therapy
chemical_list: D000995:Antitubercular Agents