Fast magnetic resonance spectroscopic imaging at 3 Tesla using autocalibrating parallel technique.
Magnetic resonance spectroscopic imaging (MRSI) is a powerful tool for diagnosis of many pathologic conditions. However conventional MRSI involves long scan times, in the order of 20 minutes. This work simulated an autocalibrating parallel technique based on GRAPPA algorithm for accelerating MRSI and applied it to 3 dimensional (3D) MRSI of the brain at 3 Tesla. Employing two fold undersampling in two phase-encoding directions, a four fold reduction in scantime was simulated. Metabolic parameters showed close agreement between the full and GRAPPA reconstructed spectral data.
Banerjee
Suchandrima
S
Joint Graduate Group in Bioeng., California Univ., Berkeley, San Francisco, CA, USA.
Ozturk-Isik
Esin
E
Nelson
Sarah J
SJ
Majumdar
Sharmila
S
D000465:Algorithms; D001224:Aspartic Acid / Q000031:analogs & derivatives* / Q000032:analysis; D001921:Brain / Q000033:anatomy & histology* / Q000378:metabolism*; D002138:Calibration; D002794:Choline / Q000032:analysis*; D006801:Humans; D007090:Image Interpretation, Computer-Assisted / Q000379:methods* / Q000592:standards; D008279:Magnetic Resonance Imaging / Q000379:methods* / Q000592:standards; D009682:Magnetic Resonance Spectroscopy / Q000379:methods* / Q000592:standards; D014018:Tissue Distribution
D001224:Aspartic Acid; C000179:N-acetylaspartate; D002794:Choline