[Use of diafiltration in the lavage of cultures of Leptospira interrogans canicola canicola for the production of vaccine vax-SPIRAL].
It was proposed to substitute the present technology of the lavage operation for a tangential microfiltration system at the lavage stages of the culture of Leptospira interrogans canicola canicola. It was proved that this system may be applied, since no cellular affectation was observed and high pollutant elimination levels were obtained.
Enrique
Kenia Fernández
KF
Instituto Finlay, Ciudad de La Habana, Cuba.
Zamora
José Daniel Benitez
JD
Gutiérrez
Raúl Boué
RB
Torres
Florinda Hernández
FH
Airado
Janet Lazo
JL
Hernández
Damián Rojo
DR
D001428:Bacterial Vaccines / Q000191:economics / Q000276:immunology / Q000592:standards; D001431:Bacteriological Techniques; D003462:Cuba; D005374:Filtration; D006801:Humans; D041341:Leptospira interrogans serovar canicola / Q000254:growth & development* / Q000276:immunology*; D007922:Leptospirosis / Q000517:prevention & control*; D013997:Time Factors
D001428:Bacterial Vaccines