title: [Early rheumatoid arthritis (ERA) diagnosis].
abstract: The rheumatoid arthritis (RA) diagnosis is based on the ARA criteria, even though the radiological joint erosions are often a requirement to make a definite diagnosis. The early rheumatoid arthritis (ERA) concept was thought of following the poor therapeutic response of the established RA. The "window of opportunity" is defined as a time frame in the early phase of the disease in which the therapeutic response is favoured, and thus giving a real chance to modify the course and the prognosis of RA. To achieve such a goal, new imaging modalities have been developed (MRI and Musculoskeletal ultrasonography--MSU), together with new serologic, inflammatory markers, genetic tests and taking into account the environmental impact (such as tobacco smokers). Such an issue can be achieved with a tight collaboration between the primary care physician and the rheumatology speciality care.
authors.affiliation: Clinique de Rhumatologie, C.H.U. Brugmann, Bruxelles.
authors.forename: J
authors.initials: J
authors.lastname: Bentin
mesh_terms: D000293:Adolescent; D017668:Age of Onset; D001171:Arthritis, Juvenile / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000628:therapy; D015415:Biomarkers / Q000032:analysis; D002097:C-Reactive Protein / Q000032:analysis; D002648:Child; D002675:Child, Preschool; D003937:Diagnosis, Differential; D006801:Humans; D008279:Magnetic Resonance Imaging; D011859:Radiography; D014463:Ultrasonography
chemical_list: D015415:Biomarkers; D002097:C-Reactive Protein