Lewis acid- and organocatalyst-cocatalyzed multicomponent reactions of 2-alkynylbenzaldehydes, amines, and ketones.
One-pot combination of silver triflate and proline catalysis is highly effective for the synthesis of 1,2-dihydroisoquinoline derivatives via multicomponent reactions of 2-alkynylbenzaldehydes, amines, and ketones.
Ding
Qiuping
Q
Department of Chemistry, Fudan University, 220 Handan Road, Shanghai 200433, China.
Wu
Jie
J
D000588:Amines / Q000737:chemistry*; D001547:Benzaldehydes / Q000737:chemistry*; D002384:Catalysis; D007546:Isoquinolines / Q000138:chemical synthesis* / Q000737:chemistry; D007659:Ketones / Q000737:chemistry*; D008698:Mesylates / Q000737:chemistry*; D015394:Molecular Structure; D011392:Proline / Q000737:chemistry*
D000588:Amines; D001547:Benzaldehydes; C109853:G 1617; D007546:Isoquinolines; D007659:Ketones; D008698:Mesylates; D011392:Proline; C012077:trifluoromethanesulfonic acid