Acne arising in an epidermal nevus.
Epidermal nevi are benign congenital lesions that follow Blaschko lines. Epidermal nevi can demonstrate a variety of histologic patterns and contain hamartomatous hyperplasia of any epidermal or adnexal structure. We present the first reported instance of acne arising strictly within a preexisting keratinocytic epidermal nevus during puberty, which is a demonstration of genetic mosaicism in pilosebaceous units.
Hivnor
Chad M
CM
Nellis Air Force Base, Nevada 89191, USA. Chad.Hivnor@nellis.af.mil
Yan
Albert C
AC
Honig
Paul J
PJ
D000152:Acne Vulgaris / Q000209:etiology* / Q000235:genetics / Q000473:pathology*; D000293:Adolescent; D004817:Epidermis / Q000473:pathology; D006801:Humans; D008297:Male; D009030:Mosaicism; D009506:Nevus / Q000150:complications* / Q000235:genetics / Q000473:pathology*; D010641:Phenotype