title: Evaluation of committed effective doses from internal contamination of 241Am using experimentally determined parameters of the contaminant.
abstract: Internal contamination of workers with 241Am has occurred a few times since the beginning of the 1970s, mainly in the workplace where radionuclide sources were produced, and later on, also during liquidation of radioactive waste. Contamination in workers was measured in vivo and bioassay was performed. Solubility of aerosol in lungs was studied by in vitro dissolution test with a simulant solution of the extracellular airway lining fluids. Model calculation for the estimation of intakes was done with the experimentally obtained parameters of aerosol, with modified times of intake, with scattering factors, including Types A and B errors, and with corrections on skull size for in vivo measurements. For most cases, an acceptable fit to the experimental data was obtained; for two cases with intakes taking place long time ago ( approximately 30 y), some changes in the model are necessary.
authors.affiliation: National Radiation Protection Institute, Srobárova 48, 100 00 Prague 10, Czech Republic. irena.malatova@suro.cz
authors.forename: I
authors.initials: I
authors.lastname: Malátová
authors.forename: V
authors.initials: V
authors.lastname: Becková
authors.forename: T
authors.initials: T
authors.lastname: Vrba
mesh_terms: D000576:Americium / Q000032:analysis* / Q000493:pharmacokinetics*; D001681:Biological Assay / Q000379:methods*; D001822:Body Burden; D003198:Computer Simulation; D018153:Czech Republic; D004781:Environmental Exposure / Q000706:statistics & numerical data*; D006801:Humans; D008954:Models, Biological; D009688:Nuclear Reactors; D016273:Occupational Exposure / Q000032:analysis*; D012062:Relative Biological Effectiveness; D014915:Whole-Body Counting / Q000706:statistics & numerical data*
chemical_list: D000576:Americium