Synthesis of 2,4,6-tri-substituted-1,3,5-triazines.
Several specific synthetic protocols were developed for the preparation from cyanuric chloride of a range of symmetric and non-symmetric di- and tri-substituted 1,3,5-triazines containing alkyl, aromatic, hindered, chiral and achiral hydroxyalkyl, ester and imidazole groups via sequential nucleophilic substitution of the C-Cl bond by C-O, C-N and C-S bonds.
Afonso
Carlos A M
CA
CQFM, Departamento de Engenharia Química, Instituto Superior Técnico, 1049-001 Lisboa, Portugal. carlosafonso@ist.utl.pt
Lourenço
Nuno M T
NM
Rosatella
Andreia de A
Ade A
D008954:Models, Biological; D014227:Triazines / Q000138:chemical synthesis* / Q000737:chemistry
D014227:Triazines; C019309:cyanuric chloride; C004632:cyanuric acid; C011907:melamine