title: Bonding BisGMA to dentin--a proof of concept for hydrophobic dentin bonding.
abstract: The use of TEGDMA as a diluent comonomer in the formulation of hydrophobic adhesives for ethanol wet-bonding is a concern, due to its leaching potential, higher water sorption, and bio-incompatibility. This study tested the hypothesis that hydrophobic bonding to acid-etched dentin may be accomplished with the use of ethanol-solvated BisGMA only. Phosphoric-acid-etched, oxalate-occluded, deep coronal dentin bonded under 20 cm water pressure with experimental BisGMA adhesives by ethanol wet-bonding exhibited tensile strengths that were not significantly different from that achieved with OptiBond FL bonded according to the manufacturer-recommended protocol, with similar acid-/base-resistant hybrid layers, resin tags, and nanoleakage distribution. Ethanol replacement of water-saturated dentin produced wider interfibrillar spaces, more extensive shrinkage of the collagen fibrils, and narrower hybrid layers. Experimental BisGMA adhesives provide the proof of concept that relatively hydrophobic resins may be coupled to acid-etched dentin by increasing its hydrophobic characteristics via ethanol replacement. They should be further optimized before clinical application.
authors.affiliation: Department of Oral Biology & Maxillofacial Pathology, School of Dentistry, Medical College of Georgia, Augusta, GA 30912-1129, USA. FTAY@mcg.edu
authors.forename: F R
authors.initials: FR
authors.lastname: Tay
authors.forename: D H
authors.initials: DH
authors.lastname: Pashley
authors.forename: R R
authors.initials: RR
authors.lastname: Kapur
authors.forename: M R O
authors.initials: MR
authors.lastname: Carrilho
authors.forename: Y B
authors.initials: YB
authors.lastname: Hur
authors.forename: L V
authors.initials: LV
authors.lastname: Garrett
authors.forename: K C Y
authors.initials: KC
authors.lastname: Tay
mesh_terms: D000134:Acid Etching, Dental; D017438:Bisphenol A-Glycidyl Methacrylate / Q000737:chemistry*; D001840:Dental Bonding / Q000379:methods*; D003799:Dental Stress Analysis; D003804:Dentin / Q000737:chemistry*; D003806:Dentin Permeability; D017220:Dentin-Bonding Agents / Q000737:chemistry*; D000431:Ethanol; D006801:Humans; D057927:Hydrophobic and Hydrophilic Interactions; D008422:Materials Testing; D008964:Molar, Third; D019279:Resin Cements / Q000737:chemistry*; D012997:Solvents; D013718:Tensile Strength
chemical_list: D017220:Dentin-Bonding Agents; D019279:Resin Cements; D012997:Solvents; D000431:Ethanol; D017438:Bisphenol A-Glycidyl Methacrylate