[Scale-up of the fermentation of Leptospira interrogans canicola canicola for the production of vax-SPIRAL vaccine].
The operational conditions for the production of vaccine vax-SPIRAL were established at the scale of 100 L. It was concluded that it should be carried out with an air flow of 10 L/min (0.1 vvm) and without mechanical agitation.
Zamora
José Daniel Benítez
JD
Instituto Finlay, Ciudad de La Habana, Cuba.
Enrique
Kenia Fernández
KF
Boué
Raúl Gutiérrez
RG
Torres
Florinda Hernández
FH
Airado
Janet Lazo
JL
Hernández
Damián Rojo
DR
D001428:Bacterial Vaccines / Q000191:economics / Q000592:standards; D001431:Bacteriological Techniques; D005285:Fermentation; D006801:Humans; D041341:Leptospira interrogans serovar canicola / Q000276:immunology* / Q000378:metabolism*; D007922:Leptospirosis / Q000517:prevention & control*; D013997:Time Factors
D001428:Bacterial Vaccines