Reactivity of methemoglobin immobilized on TiO2 nanoparticle films.
Facile demetallation occurs upon contact of the methemoglobin with a mesoporous TiO2 host in phosphate buffer media at pH 5.5 but not in acetate buffer media. As a result, voltammetric signals previously attributed to hemoglobin-based redox processes have to be re-interpreted.
Milsom
Elizabeth V
EV
Department of Chemistry, University of Bath, Claverton Down, Bath BA2 7AY, UK.
Dash
Hayley A
HA
Jenkins
A Toby A
AT
Opallo
Marcin
M
Marken
Frank
F
D000085:Acetates / Q000737:chemistry; D002021:Buffers; D004563:Electrochemistry; D004566:Electrodes; D053768:Metal Nanoparticles / Q000737:chemistry*; D008706:Methemoglobin / Q000737:chemistry*; D010084:Oxidation-Reduction; D010710:Phosphates / Q000737:chemistry; D016062:Porosity; D014025:Titanium / Q000737:chemistry*
D000085:Acetates; D002021:Buffers; D010710:Phosphates; C009495:titanium dioxide; D008706:Methemoglobin; D014025:Titanium