title: Increased resolution macular thickness mapping by OCT.
abstract: Optical coherence tomography (OCT) poor mapping resolution has been pointed out as the biggest disadvantage of this technique when compared to others, e.g., retinal thickness analyzer. In this work we were able to solve this problem by developing an atlas of macular thickness of the human retina into which OCT scans were thereafter registered. This atlas is used to allow registering OCT scans from the Fast Macular Protocol, thus bringing OCT scans into the atlas coordinates, therefore correcting for misfixations, while simultaneously allowing to perform OCT inter-scan registration. From this initial registration, we were able to compute a thickness map into which Fast RNFL Protocol scans were merged, thus allowing for increased OCT mapping resolution.
authors.affiliation: Medicina da Associação, Centro de Novas Tecnologias, AIBILI/CNTM, Coimbra, Portugal. rcb@aibili.pt
authors.forename: Rui
authors.initials: R
authors.lastname: Bernardes
authors.forename: Torcato
authors.initials: T
authors.lastname: Santos
authors.forename: José
authors.initials: J
authors.lastname: Cunha-Vaz
mesh_terms: D003196:Computer Graphics; D003941:Diagnostic Techniques, Ophthalmological; D005123:Eye / Q000033:anatomy & histology / Q000473:pathology; D006801:Humans; D007090:Image Interpretation, Computer-Assisted / Q000295:instrumentation*; D008266:Macula Lutea / Q000473:pathology*; D015233:Models, Statistical; D019721:Ophthalmoscopes; D009901:Optic Nerve Diseases / Q000473:pathology; D012160:Retina / Q000473:pathology*; D013997:Time Factors; D041623:Tomography, Optical Coherence / Q000295:instrumentation* / Q000379:methods