title: Maximising the highs and minimising the lows: harm reduction guidance within ecstasy distribution networks.
abstract: BACKGROUND
  Little is known about how users build and share knowledge concerning the highs and lows of Ecstasy and the role that Ecstasy sellers play in the exchange of this information.
  
  
  METHODS
  These findings are based on a National Institute on Drug Abuse-funded project, "An Exploratory Study of Ecstasy Distribution," conducted between 2003 and 2006. We completed in-depth interviews with 120 men and women in the San Francisco Bay Area who had sold 5 or more doses 5 or more times in the 6 months prior to the interview. The research focused on buyer-seller relationships and the influence of these relationships on users' health.
  
  
  RESULTS
  Users constructed harm reduction strategies in attempts to maximise the Ecstasy high and minimise the risks. The social context of Ecstasy use allowed for the exchange of harm reduction information and advice on how to maximise the pleasurable aspects of Ecstasy. Some participants served as "guides" to ensure that their customers had safe and enjoyable experiences while using Ecstasy.
  
  
  CONCLUSIONS
  These findings suggest that Ecstasy sellers are important points of intervention for the dissemination of harm reduction information as friendship networks were the primary link in creating awareness of safer Ecstasy use.
authors.affiliation: Institute for Scientific Analysis, 390 Fourth Street, 2nd Floor, Suite D, San Francisco, CA 94107, USA. camilleaj7@aol.com
authors.forename: Camille
authors.initials: C
authors.lastname: Jacinto
authors.forename: Micheline
authors.initials: M
authors.lastname: Duterte
authors.forename: Paloma
authors.initials: P
authors.lastname: Sales
authors.forename: Sheigla
authors.initials: S
authors.lastname: Murphy
mesh_terms: D000328:Adult; D019969:Amphetamine-Related Disorders / Q000523:psychology*; D001294:Attitude to Health; D017004:Codependency, Psychological; D005260:Female; D040261:Harm Reduction; D006801:Humans; D007407:Interviews as Topic; D008297:Male; D008875:Middle Aged; D018817:N-Methyl-3,4-methylenedioxyamphetamine / Q000009:adverse effects* / Q000600:supply & distribution*; D010465:Perception; D036301:Qualitative Research; D040242:Risk Reduction Behavior; D012309:Risk-Taking; D012495:San Francisco
chemical_list: D018817:N-Methyl-3,4-methylenedioxyamphetamine