Epidemiological survey of Kawasaki disease in Sichuan province of China.
OBJECTIVE
To investigate the incidence and epidemiological characteristics of Kawasaki Disease (KD) in Sichuan province of China.


METHODS
The questionnaire and diagnostic guideline for KD provided by Japan Kawasaki Disease Research Center (JKDRC) were used for the questionnaire investigation in pediatric departments of all hospitals in Sichuan province for data of KD diagnosed in their hospitals from 1 January 1997 to 31 December 2001.


RESULTS
Of the 212 hospitals investigated, 91.5% responded to the questionnaire investigation, with a total of 1811 cases of KD identified. The incidence per 100,000 children <5 years of age was 4.26 in 1997, 5.21 in 1998, 8.57 in 1999, 7.70 in 2000 and 9.81 in 2001, respectively. The average incidence throughout the 5 years was 7.06 per 100 000. The ratio of male to female was 1.62 : 1. The age distribution showed a peak near 1-2 years of age. Cardiac sequelae were seen in 17.0% of the patients. Only 66.2% patients with KD had been treated with intravenous immunoglobulin.


CONCLUSIONS
The incidence of KD in Sichuan province was lower than that reported in Japan and Beijing, higher than that in Guangdong, Jiangsu and Shanxi province of China.
Li
Xiao-hui
XH
Chengdu Children's Hospital, Chengdu, Sichuan, China. Lixiaohi@hotmail.com
Li
Xiao-jing
XJ
Li
Hui
H
Xu
Ming
M
Zhou
Ming
M
D017677:Age Distribution; D002675:Child, Preschool; D002681:China / Q000453:epidemiology; D004812:Epidemiologic Methods; D005260:Female; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use; D015994:Incidence; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D009080:Mucocutaneous Lymph Node Syndrome / Q000188:drug therapy / Q000453:epidemiology* / Q000503:physiopathology; D017678:Sex Distribution; D011795:Surveys and Questionnaires
D016756:Immunoglobulins, Intravenous