title: Enemas during labour.
abstract: BACKGROUND
  The use of enemas during labour usually reflects the preference of the attending healthcare provider. However, enemas may cause discomfort for women and increase the costs of delivery.
  
  
  OBJECTIVE
  To assess the effects of enemas applied during the first stage of labour on infection rates in mothers and newborns, duration of labour, perineal wound dehiscence in the mother, perineal pain and faecal soiling.
  
  
  METHODS
  We searched the Cochrane Pregnancy and Childbirth Group's Trials Register (March 2007), PubMed (1966 to December 2006), the Cochrane Central Register of Controlled Trials and Database of Abstracts of Reviews of Effectiveness (The Cochrane Library 2006, Issue 4), clinical trials registers (December 2006) and reference lists of articles.
  
  
  METHODS
  Randomized controlled trials (RCTs) in which an enema was administered during the first stage of labour and which included assessment of possible neonatal or puerperal morbidity or mortality.
  
  
  METHODS
  Two review authors assessed studies for inclusion independently.
  
  
  RESULTS
  Three RCTs (1765 women) met the inclusion criteria. Meta-analysis revealed no significant differences for infection rates in puerperal women (2 RCTs; 594 women; relative risk (RR) 0.66, 95% CI 0.42 to 1.04) or newborn children (1 RCT; 370 newborns; RR 1.12, 95% CI 0.76 to 1.67) after one month of follow up. No significant differences were found in the incidence of lower or upper respiratory tract infections. One trial described labour to be significantly shorter with enema versus no enema (1 RCT, 1027 women; 409.4 minutes versus 459.8 minutes; weighted mean difference (WMD) -50,40 CI 95% -75.68 to -25.12; P < 0.001), but another, adjusted for parity, did not confirm this (median 515 minutes with enemas versus 585 minutes without enemas, P = 0.24). Two trials found no significant differences in neonatal umbilical infection (2 RCTs; 592 newborns; RR 3.16 95% CI 0.50 to 19.82). The one trial that researched women's views found no significant differences in satisfaction between groups.
  
  
  CONCLUSIONS
  The evidence provided by the three included RCTs shows that enemas do not have a significant effect on infection rates such as perineal wound infection or other neonatal infections and women's satisfaction. This evidence does not support the routine use of enemas during labour; therefore, such practice should be discouraged.
authors.affiliation: Fundación Universitaria Sánitas, Research Institute - School of Medicine, Av Calle 127 # 21 - 60 Cons 221, Bogota, Colombia. lureveiz@colsanitas.com
authors.forename: L
authors.initials: L
authors.lastname: Reveiz
authors.forename: H G
authors.initials: HG
authors.lastname: Gaitán
authors.forename: L G
authors.initials: LG
authors.lastname: Cuervo
mesh_terms: D004733:Enema; D005260:Female; D006801:Humans; D007747:Labor Stage, First; D011247:Pregnancy; D016032:Randomized Controlled Trials as Topic; D012306:Risk