Advanced glycation end products, diabetes and ageing.
Advanced glycation end products (AGEs) are formed in vivo by a non-enzymatic reaction of proteins with carbohydrates and accumulate in many tissues during ageing. They are discussed as being responsible for many age- and diabetes-related diseases. On the other hand, AGEs are formed by the heating of food and are taken up by the nutrition. The contribution of endogenously formed versus exogenous intake of AGEs to age-related diseases is still under discussion.
Nass
N
N
Klinik für Herz- und Thoraxchirurgie, Martin-Luther-Universität Halle-Wittenberg, 06120, Halle, Germany.
Bartling
B
B
Navarrete Santos
A
A
Scheubel
R J
RJ
Börgermann
J
J
Silber
R E
RE
Simm
A
A
D000375:Aging / Q000378:metabolism* / Q000473:pathology*; D003920:Diabetes Mellitus / Q000378:metabolism* / Q000473:pathology*; D017127:Glycation End Products, Advanced / Q000378:metabolism*; D006801:Humans; D008954:Models, Biological; D015398:Signal Transduction
D017127:Glycation End Products, Advanced