title: Aptamers as molecular recognition elements for electrical nanobiosensors.
abstract: Recent advances in nanotechnology have enabled the development of nanoscale sensors that outperform conventional biosensors. This review summarizes the nanoscale biosensors that use aptamers as molecular recognition elements. The advantages of aptamers over antibodies as sensors are highlighted. These advantages are especially apparent with electrical sensors such as electrochemical sensors or those using field-effect transistors.
authors.affiliation: Fusion-Biotechnology Research Center, Advanced Materials Division, Korea Research Institute of Chemical Technology, 100 Jang-dong, Yuseong-gu, Daejeon, 305-343, South Korea. jolee@krict.re.kr
authors.forename: Jeong-O
authors.initials: JO
authors.lastname: Lee
authors.forename: Hye-Mi
authors.initials: HM
authors.lastname: So
authors.forename: Eun-Kyoung
authors.initials: EK
authors.lastname: Jeon
authors.forename: Hyunju
authors.initials: H
authors.lastname: Chang
authors.forename: Keehoon
authors.initials: K
authors.lastname: Won
authors.forename: Yong Hwan
authors.initials: YH
authors.lastname: Kim
mesh_terms: D052157:Aptamers, Nucleotide; D015374:Biosensing Techniques; D004563:Electrochemistry; D036103:Nanotechnology
chemical_list: D052157:Aptamers, Nucleotide