When is elevated testosterone not testosterone? When it is an immunoassay interfering antibody.
A discrepancy between clinical findings and a markedly elevated testosterone (T) level stimulated search to explain this inconsistency. The cause of the falsely elevated T level was determined to be heterophile antibodies from a polyclonal gammopathy in a subject with acute myelogenous leukemia.
Ramaeker
Devon
D
Department of Obstetrics and Gynecology, Magee-Women's Hospital, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Brannian
John
J
Egland
Kristi
K
McCaul
Kelly
K
Hansen
Keith
K
D000328:Adult; D016477:Artifacts; D003951:Diagnostic Errors / Q000517:prevention & control*; D005189:False Positive Reactions; D005260:Female; D006801:Humans; D007118:Immunoassay / Q000379:methods*; D007246:Infertility / Q000097:blood* / Q000175:diagnosis*; D013739:Testosterone / Q000097:blood*
D013739:Testosterone