[Multiple sclerosis: study of patients with relapsing-remitting form registered at Minas Gerais Secretary of State for Health].
Multiple sclerosis is a chronic inflammatory demyelinating disease of the central nervous system. The recommended treatment for the relapsing-remitting form is carried out with the immunomodulatory drugs, which are provided, in Belo Horizonte, by Minas Gerais Secretary of State for Health (MG/SSH). We analyzed data of 283 patients registered at Exceptional Drug Program (immunomodulators) of SES/MG from May to October 2004. There was predominance of females (3.7:1) and the mean age was 38.4 +/-10.7 years old. The first clinical manifestations were 29.7+/-10.2 years old. The initial symptoms included sensorial (46.4%), visual (33.1%), brainstem/cerebellar syndromes (30.1%) and motor (pyramidal) syndrome (25.9%). The symptoms observed in subsequent relapses were motor (22.3%), brainstem/cerebellar syndromes (18.9%), visual (18.9%) and sensorial findings (9.6%). In 234 brain MRI and 109 spine MRI there were demyelinating lesions at 97.4% and 85.3% respectively. We compared our findings with other series described on Brazilian literature.
Santos
Eustáquio Claret dos
EC
Coordenadoria de Alta Complexidade, Diretoria de Redes Assistenciais, Secretaria de Estado da Saúde de Minas Gerais, Rua Domingos Vieira 273/907, 30150-240 Belo Horizonte, MG, Brazil. ecsantos@fcs.fumec.br
Yokota
Mitico
M
Dias
Nádia Fernanda Rezende
NF
D000293:Adolescent; D000328:Adult; D000368:Aged; D001938:Brazil / Q000453:epidemiology; D002648:Child; D005260:Female; D006801:Humans; D007155:Immunologic Factors / Q000627:therapeutic use; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D020529:Multiple Sclerosis, Relapsing-Remitting / Q000188:drug therapy / Q000453:epidemiology*
D007155:Immunologic Factors