title: Surgical strategy in aortoesophageal fistulae: endovascular stentgrafts and in situ repair of the aorta with cryopreserved homografts.
abstract: OBJECTIVE
  The surgical treatment of aortoesophageal fistulae (AEF) has a high morbidity and mortality rate. We report our experience with the sequential use of endovascular thoracic stentgrafts and cryopreserved aortic homografts for in situ repair of the descending thoracic aorta.
  
  
  METHODS
  In a 7-year period, 6 patients with AEF were treated at our center. After primary endovascular repair in all cases, 4 patients subsequently underwent in situ repair of the descending thoracic aorta with cryopreserved homografts. Long-term antibiotic therapy was given in all cases. Recent clinical status and radiologic findings on follow-up studies of each patient were analyzed. The mean follow-up time was 35 months (range, 2-76).
  
  
  RESULTS
  Endovascular stentgraft repair was technically successful in all cases. Two patients were not candidates for open surgical repair because of their medical condition; they both died within 8 weeks after discharge from the hospital, 1 from recurrent septic episodes, and the other from upper gastrointestinal bleeding. One of 4 patients who had undergone open surgical repair died 1 year later from upper gastrointestinal bleeding that occurred presumably due to an infectious degeneration of the homograft after secondary infection with a methacillin-resistant Staphyloccocus aureus. In 1 case persistent paraplegia and in another case persistent renal failure occurred.
  
  
  CONCLUSIONS
  The use of cryopreserved homografts is a valuable alternative to in situ repair with prosthetic vascular grafts or extra-anatomic reconstructions in the surgical treatment of AEF. Endovascular stentgraft placement plays a role as a bridging procedure in emergency situations.
authors.affiliation: Vascular Surgery/Department of Surgery, University of Regensburg Medical Center, University of Regensburg, Regensburg, Germany. itoepel@web.de
authors.forename: Ingolf
authors.initials: I
authors.lastname: Topel
authors.forename: Alexander
authors.initials: A
authors.lastname: Stehr
authors.forename: Markus G
authors.initials: MG
authors.lastname: Steinbauer
authors.forename: Pompilio
authors.initials: P
authors.lastname: Piso
authors.forename: Hans J
authors.initials: HJ
authors.lastname: Schlitt
authors.forename: Piotr M
authors.initials: PM
authors.lastname: Kasprzak
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D017130:Angioplasty / Q000379:methods*; D001018:Aortic Diseases / Q000209:etiology / Q000601:surgery*; D015925:Cryopreservation; D004937:Esophageal Fistula / Q000209:etiology / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D015607:Stents; D016378:Tissue Transplantation / Q000379:methods*; D016896:Treatment Outcome; D016157:Vascular Fistula / Q000209:etiology / Q000601:surgery*