title: Partially parallel MR spectroscopic imaging of gliomas at 3T.
abstract: Magnetic resonance spectroscopic imaging (MRSI) has been used to more accurately diagnose, localize, and assess progression and treatment response for gliomas. The main limitation of the MRSI is the long data acquisition times. A current approach is to reduce the amount of k-space data sampled by limiting the data acquisition to a central elliptical portion of k-space. This study investigated the feasibility of reducing the data acquisition time further for the MRSI data using two parallel imaging techniques and investigating the relative performance of sensitivity encoding (SENSE) and generalized autocalibrating partially parallel acquisitions (GRAPPA).
authors.affiliation: UCSF/UCB Joint Graduate Group in Bioengineering, University of California, San Francisco, CA, USA. esin.ozturk@mrsc.ucsf.edu
authors.forename: Esin
authors.initials: E
authors.lastname: Ozturk
authors.forename: Suchandrima
authors.initials: S
authors.lastname: Banerjee
authors.forename: Sharmila
authors.initials: S
authors.lastname: Majumdar
authors.forename: Sarah J
authors.initials: SJ
authors.lastname: Nelson
mesh_terms: D001224:Aspartic Acid / Q000031:analogs & derivatives / Q000032:analysis; D014408:Biomarkers, Tumor / Q000032:analysis*; D001921:Brain / Q000378:metabolism* / Q000473:pathology*; D001932:Brain Neoplasms / Q000175:diagnosis* / Q000378:metabolism*; D002794:Choline / Q000032:analysis; D003401:Creatine / Q000032:analysis; D005910:Glioma / Q000175:diagnosis* / Q000378:metabolism*; D007090:Image Interpretation, Computer-Assisted / Q000379:methods; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity
chemical_list: D014408:Biomarkers, Tumor; D001224:Aspartic Acid; C000179:N-acetylaspartate; D003401:Creatine; D002794:Choline