Selective enzymatic reduction of aldehydes.
Highly selective enzymatic reductions of aldehydes to the corresponding alcohols was performed using an E. coli JM109 whole cell biocatalyst. A selective enzymatic method for the reduction of aldehydes could provide an eco-compatible alternative to chemical methods. The simplicity, fairly wide scope and the very high observed chemoselectivity of this approach are its most unique features.
Sello
Guido
G
Dipartimento di Chimica Organica e Industriale, Università degli Studi di Milano, via Venezian 21, 20133 Milano, Italy. guido.sello@unimi.it
Orsini
Fulvia
F
Bernasconi
Silvana
S
Di Gennaro
Patrizia
P
D000447:Aldehydes / Q000378:metabolism*; D002384:Catalysis; D004798:Enzymes / Q000378:metabolism*; D004926:Escherichia coli / Q000201:enzymology; D010084:Oxidation-Reduction
D000447:Aldehydes; D004798:Enzymes