title: Separation of subcortical component from cortical auditory evoked potential by independent component analysis.
abstract: Auditory evoked potentials (AEPs) in the temporal cortex have typical slow positive/negative (P1/N1) biphasic waves, which are occasionally associated with an additional earlier small deflection (P0/N0). In the present paper, we attempted to address the neural origin of P0/N0 deflection by the independent component analysis (ICA) of densely mapped cortical AEPs of rats. The ICA results suggest that the deflection appears when subcortical contribution to AEP is equal to or larger than cortical contribution.
authors.affiliation: Graduate School of Information Science and Technology, University of Tokyo, Japan. takahashi@u-tokyo.ac.jp
authors.forename: Hirokazu
authors.initials: H
authors.lastname: Takahashi
authors.forename: Masayuki
authors.initials: M
authors.lastname: Nakao
authors.forename: Kimitaka
authors.initials: K
authors.lastname: Kaga
mesh_terms: D000465:Algorithms; D000818:Animals; D001303:Auditory Cortex / Q000502:physiology*; D001931:Brain Mapping / Q000379:methods*; D004569:Electroencephalography / Q000379:methods*; D005072:Evoked Potentials, Auditory / Q000502:physiology*; D010363:Pattern Recognition, Automated / Q000379:methods*; D025341:Principal Component Analysis; D051381:Rats; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity