title: [Study on the inclusion technology of volatile oil in Shiquandabu pills].
abstract: OBJECTIVE
  To extract volatile oil from Shiquandabu pills and study technological process of its inclusion compound with beta-Cyclodextrin (beta-CD) to improve its stability.
  
  
  METHODS
  The study was carried out with steam distillation and orthogonal design. The process conditions were studied by determining the utilization and ratio of oil from Shiquandabu pills volatile oil and extract ratio of in-clusion compound. The most important factor was the ratio of oil to beta-CD. and the inclusion compound was identified by FT-IR spectra and XRD.
  
  
  RESULTS
  The optimum preparation conditions for inclusion were best-established as oil: beta-CD was 1:8, the inclusion time and temperature were for 1.0 hours. at 20 degrees C.
  
  
  CONCLUSIONS
  Tne method can be used for increasing volatile oil's stability and its solubility. It is suitable for production of medicinal preparation.
authors.affiliation: Department of Pharmaceutical Engineering, School of Chemical Engineering, Wuhan University of Technology, Wuhan 430070, China.
authors.forename: Hai-xing
authors.initials: HX
authors.lastname: Xu
authors.forename: Xiao-ping
authors.initials: XP
authors.lastname: Liu
authors.forename: Yun-xia
authors.initials: YX
authors.lastname: Gong
mesh_terms: D000704:Analysis of Variance; D004337:Drug Carriers; D004338:Drug Combinations; D004355:Drug Stability; D004365:Drugs, Chinese Herbal / Q000032:analysis / Q000737:chemistry*; D009822:Oils, Volatile / Q000032:analysis / Q000737:chemistry / Q000302:isolation & purification*; D010946:Plants, Medicinal / Q000737:chemistry; D015203:Reproducibility of Results; D012995:Solubility; D013055:Spectrophotometry, Infrared; D013607:Tablets; D013678:Technology, Pharmaceutical / Q000379:methods*; D013696:Temperature; D013997:Time Factors; D047392:beta-Cyclodextrins / Q000737:chemistry*
chemical_list: D004337:Drug Carriers; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal; D009822:Oils, Volatile; D013607:Tablets; D047392:beta-Cyclodextrins; C530444:shiquandabu