title: Software for interpreting cardiopulmonary exercise tests.
abstract: BACKGROUND
  Cardiopulmonary exercise testing (CPET) has become an important modality for the evaluation and management of patients with a diverse array of medical problems. However, interpreting these tests is often difficult and time consuming, requiring significant expertise.
  
  
  METHODS
  We created a computer software program (XINT) that assists in CPET interpretation. The program uses an integrative approach as recommended in the Official Statement of the American Thoracic Society/American College of Chest Physicians (ATS/ACCP) on Cardiopulmonary Exercise Testing. In this paper we discuss the principles behind the software. We also provide the detailed logic in an accompanying file (Additional File 1). The actual program and the open source code are also available free over the Internet at http://www.xint.org. For convenience, the required download files can also be accessed from this article.
  
  
  RESULTS
  To test the clinical usefulness of XINT, we present the computer generated interpretations of the case studies discussed in the ATS/ACCP document in another accompanying file (Additional File 2). We believe the interpretations are consistent with the document's criteria and the interpretations given by the expert panel.
  
  
  CONCLUSIONS
  Computers have become an integral part of modern life. Peer-reviewed scientific journals are now able to present not just medical concepts and experimental studies, but actual functioning medical interpretive software. This has enormous potential to improve medical diagnoses and patient care. We believe XINT is such a program that will give clinically useful interpretations when used by the medical community at large.
authors.affiliation: Department of Medicine, Baylor College of Medicine, Houston, Texas 77030, USA. rross@bcm.tmc.edu
authors.forename: Robert M
authors.initials: RM
authors.lastname: Ross
authors.forename: David B
authors.initials: DB
authors.lastname: Corry
mesh_terms: D000402:Airway Obstruction / Q000175:diagnosis; D015308:Anaerobic Threshold; D002318:Cardiovascular Diseases / Q000175:diagnosis; D015444:Exercise / Q000502:physiology; D005080:Exercise Test / Q000592:standards*; D006331:Heart Diseases / Q000175:diagnosis* / Q000503:physiopathology; D006339:Heart Rate; D006801:Humans; D008171:Lung Diseases / Q000175:diagnosis* / Q000503:physiopathology; D010101:Oxygen Consumption; D011659:Pulmonary Gas Exchange; D012016:Reference Values; D015656:Respiratory Mechanics; D012984:Software; D013318:Stroke Volume