title: [Human seminal plasma allergy type I].
abstract: Human seminal plasma allergy (HSPA) is a rare allergic reaction to specific protein fractions of seminal plasma, whereof PSA seems to be a relevant allergen. Predominantly Type I-immunoreactions can occur. The main symptoms are localized and generalized urticaria and sometimes anaphylactic symptoms. The diagnosis is based on history, skin tests and on the determination of specific IgE-levels for (un)fractionated seminal plasma. Here we report a patient with recurrent episodes of generalized urticaria after unprotected sexual intercourse and positive prick-test-reaction on seminal plasma.
authors.affiliation: Klinik für Dermatologie, Venerologie und Allergologie, Universitätsklinikum Leipzig AöR, Philipp-Rosenthal-Str. 23-25, 04103 Leipzig. ulrike.winter@medizin.uni-leipzig.de
authors.forename: U M
authors.initials: UM
authors.lastname: Winter
authors.forename: W
authors.initials: W
authors.lastname: Harth
authors.forename: R
authors.initials: R
authors.lastname: Treudler
authors.forename: J C
authors.initials: JC
authors.lastname: Simon
mesh_terms: D000328:Adult; D017280:Condoms; D003888:Desensitization, Immunologic; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D006969:Hypersensitivity, Immediate / Q000175:diagnosis / Q000209:etiology* / Q000276:immunology / Q000628:therapy; D007428:Intradermal Tests; D012661:Semen / Q000276:immunology*; D014581:Urticaria / Q000175:diagnosis / Q000209:etiology* / Q000276:immunology / Q000628:therapy; D014847:Vulvitis / Q000175:diagnosis / Q000209:etiology* / Q000276:immunology / Q000628:therapy