Hyaluronic acid versus albumin in human embryo transfer medium.
We compared the implantation and pregnancy rate through in vitro fertilization (IVF) using hyaluronic acid and albumin as transfer medium in 60 women randomly allocated to 2 groups. In treatment group A (n = 30), embryos were transferred to medium supplemented with hyaluronic acid. In the control group B (n = 30), embryos were transferred to medium containing albumin. There were no significant differences between the groups in terms of mean age of the females, mean duration of infertility and mean number of embryos. The pregnancy rate in groups A and B were 81.8% and 71.4% respectively, a non-statistically significant difference. Hyaluronic acid can successfully replace albumin as transfer medium.
Mahani
I M
IM
Department of Obstetrics and Gynaecology, Afzallipour Hospital, Kerman University of Medical Sciences, Kerman, Islamic Republic of Iran. i_mehrimahani@kmu.ac.ir
Davar
R
R
D000022:Abortion, Spontaneous / Q000453:epidemiology; D000328:Adult; D000418:Albumins / Q000592:standards; D000704:Analysis of Variance; D016009:Chi-Square Distribution; D003470:Culture Media / Q000592:standards; D004311:Double-Blind Method; D010064:Embryo Implantation; D004624:Embryo Transfer / Q000592:standards; D005260:Female; D005307:Fertilization in Vitro / Q000379:methods*; D006801:Humans; D006820:Hyaluronic Acid / Q000592:standards; D007247:Infertility, Female / Q000628:therapy; D007492:Iran / Q000453:epidemiology; D008423:Maternal Age; D010062:Ovulation Induction / Q000379:methods; D018579:Patient Selection; D011247:Pregnancy; D011256:Pregnancy Outcome / Q000453:epidemiology*; D011446:Prospective Studies; D013997:Time Factors
D000418:Albumins; D003470:Culture Media; D006820:Hyaluronic Acid