title: [Observation on effects of Zhiling Capsule in treating 400 patients with various types of cancer in mid-ad-vanced stage].
abstract: OBJECTIVE
  To observe the efficacy of Zhiling Capsule (ZLC) in improving symptoms and quality of life (QOL) in patients with various types of cancer in mid-advanced stage.
  
  
  METHODS
  A multi-centre randomized and controlled trial was conducted. Four hundred patients with mid-advanced cancer were assigned to two groups: the treatment group (300 cases) treated with ZLC and the control group (100 cases) with Pingxiao Capsule (PXC), both were given orally for two weeks. Clinical symptoms, QOL, weight and adverse reactions were observed before and after treatment.
  
  
  RESULTS
  Improving rate of symptom, increasing rates of QOL and weight in the treatment group were all higher than those in the control group (P<0.05); and no obvious adverse reaction was observed in the two groups.
  
  
  CONCLUSIONS
  ZLC could alleviate the qi-yin deficiency syndrome and pain syndrome and improve QOL in patients with various types of cancer in mid-advanced stage.
authors.affiliation: Department of Tumor, The First Hospital of Fuzhou City, Fuzhou. lanlnal155@163.com
authors.forename: Yun-Ling
authors.initials: YL
authors.lastname: Pan
authors.forename: Yuan-Zhi
authors.initials: YZ
authors.lastname: Pan
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002214:Capsules; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000503:physiopathology; D008517:Phytotherapy; D019413:Qi; D011788:Quality of Life; D016896:Treatment Outcome; D016710:Yin Deficiency / Q000188:drug therapy* / Q000473:pathology / Q000503:physiopathology
chemical_list: D002214:Capsules; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal; C533630:zhiling