Occlusive retinal vasculitis in a patient with West Nile virus.
BACKGROUND
West Nile virus (WNV) was first identified in the United States in 1999. In addition to a spectrum of systemic manifestations, several ocular conditions secondary to the virus have been reported, including chorioretinitis, uveitis and optic neuritis. Age and diabetes mellitus (DM) have been reported to be associated risk factors for the more severe forms of the systemic disease. Only seven cases of occlusive retinal vasculitis have been reported in patients with WNV infection.


METHODS
A 60-year-old Asian male presented with complaints of decreased vision in his left eye. He had been hospitalised approximately seven weeks earlier with meningo-encephalitis secondary to presumed WNV infection, at which time he was also diagnosed with DM. The visual loss coincided with the manifestation of systemic WNV infection. Old peripheral chorioretinal lesions without active inflammation in both eyes were consistent with WNV infection. In addition, retinal haemorrhage and cotton wool spots were noted in the posterior pole of both eyes with severe macular ischaemia in the left eye.


CONCLUSIONS
Occlusive retinal vasculitis is an uncommon ocular manifestation of WNV, which should be suspected in patients with meningitis or encephalitis who reside in endemic areas with ocular findings of the disease.
Teitelbaum
Bruce A
BA
Illinois College of Optometry, Chicago, Illinois, USA. bteitelb@ico.edu
Newman
Tricia L
TL
Tresley
David J
DJ
D000914:Antibodies, Viral / Q000032:analysis; D003937:Diagnosis, Differential; D005451:Fluorescein Angiography; D005654:Fundus Oculi; D006801:Humans; D008297:Male; D008875:Middle Aged; D015356:Retinal Artery Occlusion / Q000175:diagnosis / Q000209:etiology*; D031300:Retinal Vasculitis / Q000175:diagnosis / Q000209:etiology*; D014792:Visual Acuity; D014901:West Nile Fever / Q000150:complications* / Q000821:virology; D014902:West Nile virus / Q000276:immunology*
D000914:Antibodies, Viral