title: Cardiomyopathy, pericarditis and myocarditis in a population-based cohort of inpatients with coeliac disease.
abstract: OBJECTIVE
  We investigated the risk of myocarditis, cardiomyopathy, and pericarditis in patients with celiac disease (CD) from a general population cohort.
  
  
  METHODS
  Through the Swedish national registers we identified 9363 children and 4969 adults with a diagnosis of CD (1964-2003). These individuals were matched with upto five reference individuals for age, sex, calendar year and county (n = 69 851). Cox regression estimated hazard ratios (HRs) for later heart disease.
  
  
  METHODS
  Myocarditis, cardiomyopathy (any or dilated), and pericarditis defined according to relevant international classification of disease codes in the Swedish national inpatient register.
  
  
  RESULTS
  Celiac disease diagnosed in childhood was not associated with later myocarditis (HR = 0.2; 95% CI = 0.0-1.5), cardiomyopathy of any type (HR = 0.8; 95% CI = 0.2-3.7), or pericarditis (HR = 0.4; 95% CI = 0.1-1.9). Restricting our analyses to adulthood CD and heart disease diagnosed from 1987 and onwards in departments of cardiology/internal medicine, we found no association between CD and later myocarditis (HR = 2.1; 95% CI = 0.4-11.7), dilated cardiomyopathy (HR = 1.7; 95% CI = 0.4-6.5) or pericarditis (HR = 1.5; 95% CI = 0.5-4.0).
  
  
  CONCLUSIONS
  This study found no association between CD, later myocarditis, cardiomyopathy or pericarditis.
authors.affiliation: Department of Paediatrics, Orebro University Hospital, Orebro, Sweden.
authors.forename: P
authors.initials: P
authors.lastname: Elfström
authors.forename: A
authors.initials: A
authors.lastname: Hamsten
authors.forename: S M
authors.initials: SM
authors.lastname: Montgomery
authors.forename: A
authors.initials: A
authors.lastname: Ekbom
authors.forename: J F
authors.initials: JF
authors.lastname: Ludvigsson
mesh_terms: D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D009202:Cardiomyopathies / Q000150:complications / Q000453:epidemiology*; D002446:Celiac Disease / Q000150:complications / Q000453:epidemiology*; D015331:Cohort Studies; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D009205:Myocarditis / Q000150:complications / Q000453:epidemiology*; D016017:Odds Ratio; D010493:Pericarditis / Q000150:complications / Q000453:epidemiology*; D018570:Risk Assessment / Q000379:methods; D017678:Sex Distribution; D012959:Socioeconomic Factors; D013548:Sweden / Q000453:epidemiology