Microwave assisted synthesis of N-arylheterocyclic substituted-4-aminoquinazoline derivatives.
A simple, efficient, and general method has been developed for the synthesis of various N-aryl heterocylic substituted-4-aminoquinazoline compounds from 4-chloro- quinazoline and aryl heterocyclic amines under microwave irradiation using 2-propanol as solvent. The advantages of the use of microwave irradiation in relation to the classical method were demonstrated.
Liu
Gang
G
Center for Research and Development of Fine Chemicals, Guizhou University, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Guiyang, 550025, P. R. China.
Yang
Song
S
Song
Baoan
B
Xue
Wei
W
Hu
Deyu
D
Jin
Linhong
L
Lu
Ping
P
D006571:Heterocyclic Compounds / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D008872:Microwaves; D011799:Quinazolines / Q000138:chemical synthesis* / Q000737:chemistry
D006571:Heterocyclic Compounds; D011799:Quinazolines