title: [Diffraction enhanced imaging of condylar cartilage of osteoarthritic rats].
abstract: OBJECTIVE
  To observe the images of early lesions of condylar cartilage of osteoarthritic rats in synchrotron radiation diffraction enhanced imaging (DEI).
  
  
  METHODS
  The animal model of temporomandibular joint osteoarthrosis was established in rat following the method of partial resection of the joint disc. The changes of osteoarthritic condylar cartilage in different pathological stages were observed by DEI and compared with those in situ histopathological sections.
  
  
  RESULTS
  With DEI, straight and orbicular lines were detected in condylar cartilage 45 to 60 days after discs resection. The lines were confirmed by histopathology to be collagen degradation and tiny fissure formation inside the cartilage.
  
  
  CONCLUSIONS
  DEI is capable of imaging the early stages of pathological changes of excised condylar cartilage such as collagen degradation and tiny fissure formation, and this technique is of potential value to clinical application.
authors.affiliation: Department of Engineering Physics, Tsinghua University, Beijing 100084, China.
authors.forename: Chang-Hong
authors.initials: CH
authors.lastname: Cong
authors.forename: Zhi-Hua
authors.initials: ZH
authors.lastname: Chen
authors.forename: Gang
authors.initials: G
authors.lastname: Li
authors.forename: Lin
authors.initials: L
authors.lastname: Pan
authors.forename: Ji-Guang
authors.initials: JG
authors.lastname: Liu
authors.forename: Jin-Tian
authors.initials: JT
authors.lastname: Tang
mesh_terms: D000818:Animals; D002358:Cartilage, Articular / Q000000981:diagnostic imaging* / Q000473:pathology; D008297:Male; D008335:Mandibular Condyle / Q000000981:diagnostic imaging* / Q000473:pathology; D011859:Radiography; D051381:Rats; D017208:Rats, Wistar; D013705:Temporomandibular Joint Disorders / Q000000981:diagnostic imaging* / Q000473:pathology; D014961:X-Ray Diffraction / Q000379:methods*