title: Situational antiviral drug prophylaxis for HSV type 1 recurrences.
abstract: Recurrent herpes simplex virus type 1 infection is generally associated with mild morbidity. However, frequent recurrences may have a significant psychosocial impact, and reactivation in certain high-risk situations may cause considerable morbidity. Controlled trials demonstrate that antiviral drug prophylaxis can be efficacious in selected circumstances; even for other situations, clinical reports suggest that such antiviral drug prophylaxis remains effective.
authors.affiliation: Department of Dermatology, University of Utah School of Medicine, Salt Lake City, UT 84132, USA. hull@derm.med.utah.edu
authors.forename: Christopher
authors.initials: C
authors.lastname: Hull
authors.forename: Spotswood
authors.initials: S
authors.lastname: Spruance
mesh_terms: D000998:Antiviral Agents / Q000008:administration & dosage* / Q000627:therapeutic use*; D018890:Chemoprevention; D004892:Erythema Multiforme / Q000188:drug therapy / Q000517:prevention & control / Q000821:virology; D005260:Female; D006561:Herpes Simplex / Q000188:drug therapy* / Q000517:prevention & control* / Q000821:virology; D018259:Herpesvirus 1, Human / Q000187:drug effects* / Q000502:physiology; D006801:Humans; D007121:Immunocompetence; D008297:Male; D055502:Secondary Prevention; D014466:Ultraviolet Rays / Q000009:adverse effects; D014775:Virus Activation / Q000187:drug effects / Q000502:physiology
chemical_list: D000998:Antiviral Agents