Tethering small molecules to a phage display library: discovery of a selective bivalent inhibitor of protein kinase A.
Meyer
Scott C
SC
Department of Chemistry, University of Arizona, Tucson, Arizona 85721, USA.
Shomin
Carolyn D
CD
Gaj
Thomas
T
Ghosh
Indraneel
I
D001665:Binding Sites; D017868:Cyclic AMP-Dependent Protein Kinases / Q000037:antagonists & inhibitors; D008958:Models, Molecular; D008968:Molecular Conformation; D008970:Molecular Weight; D019151:Peptide Library; D047428:Protein Kinase Inhibitors / Q000737:chemistry* / Q000494:pharmacology; D017434:Protein Structure, Tertiary; D019311:Staurosporine / Q000737:chemistry* / Q000494:pharmacology; D013329:Structure-Activity Relationship
D019151:Peptide Library; D047428:Protein Kinase Inhibitors; D017868:Cyclic AMP-Dependent Protein Kinases; D019311:Staurosporine