Endoscopic management of duodenal diverticular bleeding.
BACKGROUND
Although the presence of a duodenal diverticulum is usually asymptomatic, bleeding in this tissue is sometimes difficult to diagnose and treat.


OBJECTIVE
To investigate the strategy for treatment, we reviewed the clinical data of patients diagnosed and treated for duodenal diverticular bleeding.


METHODS
Retrospective case series.


METHODS
Single tertiary-referral center.


METHODS
Seven consecutive patients with bleeding from a duodenal diverticulum (mean age, 73.7 +/- 3.4 years old).


METHODS
The clinical characteristics, endoscopic findings, and treatment strategy for duodenal diverticular bleeding.


METHODS
All 7 patients achieved hemostasis. Six of 7 patients were treated endoscopically. There were no complications with endoscopic treatment.


RESULTS
Three patients bled from diverticula located at the second portion of the duodenum, and 4 patients bled from that located at the third portion. In 6 of 7 patients, lesions were identified and treated endoscopically with hemoclips, hypertonic saline solution and epinephrine (HSE), and/or 1% polidocanol injection. In 1 case, the lesion could not be detected during the first endoscopic examination, and the patient, therefore, was treated with transarterial embolization followed by surgical resection.


CONCLUSIONS
This preliminary case series described the feasibility of the endoscopic treatment. However, optimal management, including angiography and/or surgery, should be individualized to the patients, location, and type of hemorrhage.


CONCLUSIONS
Bleeding from a duodenal diverticulum should be considered in the case of upper-GI bleeding of unknown origin. An endoscopy may be an effective alternative to surgery in the management of a bleeding duodenal diverticulum.
Onozato
Yasuhiro
Y
Center of Gastroenterology, Gunma University Graduate School of Medicine, Maebashi, Gunma, Japan.
Kakizaki
Satoru
S
Ishihara
Hiroshi
H
Iizuka
Haruhisa
H
Sohara
Naondo
N
Okamura
Shinichi
S
Mori
Masatomo
M
Itoh
Hideaki
H
D000368:Aged; D004240:Diverticulum / Q000150:complications* / Q000175:diagnosis; D004378:Duodenal Diseases / Q000473:pathology*; D005260:Female; D006471:Gastrointestinal Hemorrhage / Q000628:therapy*; D016558:Hemostasis, Endoscopic; D006801:Humans; D008297:Male; D012189:Retrospective Studies; D016896:Treatment Outcome; D041742:Upper Gastrointestinal Tract / Q000473:pathology