title: [A pediatric case of Alveolar Soft Part Sarcoma].
abstract: BACKGROUND
  Alveolar Soft Part Sarcoma (ASPS) is a rare malignant tumor arising from skeletal muscles and occurring usually in young adults. It is a solid chemo resistant tumor. At time of diagnosis the disease is usually advanced and lung metastasis are present in 65% of the cases. The translocation (X; 17), producing an ASPL-TFE3 transcript fusion which is detected on tumoral cells wall, is specific of ASPS. The curative treatment is surgical.
  
  
  METHODS
  We report the case of a child with an ASPS of the tongue and lung metastasis.
  
  
  CONCLUSIONS
  This report presents two particularities. Firstly this type of sarcoma is very exceptional in a 2-year-old child. Secondly ASPS is not usually susceptible to chemotherapy.
authors.affiliation: Service de chirurgie maxillofaciale et plastique, APHP, hôpital d'enfants Armand-Trousseau, 75012 Paris, France.
authors.forename: A
authors.initials: A
authors.lastname: Marchac
authors.forename: A
authors.initials: A
authors.lastname: Picard
authors.forename: J
authors.initials: J
authors.lastname: Landman-Parker
authors.forename: M
authors.initials: M
authors.lastname: Larroquet
authors.forename: M-P
authors.initials: MP
authors.lastname: Vazquez
authors.forename: G
authors.initials: G
authors.lastname: Franchi
mesh_terms: D017024:Chemotherapy, Adjuvant; D002675:Child, Preschool; D005500:Follow-Up Studies; D005927:Glossectomy; D006801:Humans; D008175:Lung Neoplasms / Q000556:secondary / Q000601:surgery; D008297:Male; D020360:Neoadjuvant Therapy; D009367:Neoplasm Staging; D018234:Sarcoma, Alveolar Soft Part / Q000175:diagnosis* / Q000556:secondary / Q000601:surgery; D014062:Tongue Neoplasms / Q000175:diagnosis* / Q000601:surgery