Involuting solitary cutaneous infantile myofibroma and thrombocytopaenia: a previously unreported clinical association.
Solitary and multicentric myofibromas are rare fibrous tumours with marked predilection for infants and young children. Presentation is mainly before the age of 2 and lesions are often congenital. Behaviour is usually benign, but mortality has been described in lesions with visceral involvement. We report a unique case of congenital solitary cutaneous infantile myofibroma in a neonate associated with self-limiting thrombocytopaenia. It is important to distinguish accurately these lesions from benign vascular tumours like haemangiomas, locally aggressive vascular tumours like Kaposiform haemangioendotheliomas, which are often associated with Kasabach-Merritt phenomenon and also with malignant soft tissue tumours of infancy.
Leon-Villapalos
J
J
St Andrews Centre for Plastic Surgery, Court Road, Broomfield, Chelmsford, Essex CM1 7ET, UK.
Wolfe
K
K
Calonje
E
E
Kangesu
L
L
D004200:Diseases in Twins / Q000175:diagnosis*; D006801:Humans; D007223:Infant; D008297:Male; D047708:Myofibroma / Q000175:diagnosis*; D009365:Neoplasm Regression, Spontaneous; D012878:Skin Neoplasms / Q000175:diagnosis*; D013921:Thrombocytopenia / Q000175:diagnosis*; D016896:Treatment Outcome