Childhood sarcoidosis presenting with extensive cutaneous lesions, bilateral hilar lymphadenopathy and severe hypercalcaemia.
A 9-year-old boy with a history of atopic dermatitis presented with a 4-month history of an asymptomatic papular eruption. This was predominantly perioral in distribution with lesser involvement of the neck, arms and trunk. Investigations revealed severe hypercalcaemia of 3.77 mmol/L (normal range 2.10-2.60) and bilateral hilar lymphadenopathy. The diagnosis of sarcoidosis was supported by granulomata in skin and lymph node biopsies on histopathological examination. Prednisolone (2 mg/kg/day) rapidly normalized serum calcium.
Mortimer
Neil J
NJ
Department of Dermatology, Leicester Royal Infirmary, Leicester, UK. njmort2002@yahoo.com
Sladden
Michael J
MJ
Hill
Sarah E
SE
Graham-Brown
Robin Ac
RA
D002648:Child; D006099:Granuloma / Q000473:pathology; D006801:Humans; D006934:Hypercalcemia / Q000209:etiology*; D008206:Lymphatic Diseases / Q000000981:diagnostic imaging / Q000473:pathology*; D008297:Male; D011859:Radiography; D012507:Sarcoidosis / Q000150:complications / Q000000981:diagnostic imaging / Q000473:pathology*; D012867:Skin / Q000473:pathology*