title: Advances in brain tumor surgery.
abstract: Advances in the fields of molecular and translational research, oncology, and surgery have emboldened the medical community to believe that intrinsic brain tumors may be treatable. Intraoperative imaging and brain mapping allow operations adjacent to eloquent cortex and more radical resection of tumors with increased confidence and safety. Despite these advances, the infiltrating edge of a neoplasm and distant microscopic satellite lesions will never be amendable to a surgical cure. Indeed, it is continued research into the delivery of an efficacious chemobiologic agent that will eventually allows us to manage this primary cause of treatment failure.
authors.affiliation: National Institutes of Health/NINDS, Bethesda, MD, USA. asthagiria@ninds.nih.gov
authors.forename: Ashok R
authors.initials: AR
authors.lastname: Asthagiri
authors.forename: Nader
authors.initials: N
authors.lastname: Pouratian
authors.forename: Jonathan
authors.initials: J
authors.lastname: Sherman
authors.forename: Galal
authors.initials: G
authors.lastname: Ahmed
authors.forename: Mark E
authors.initials: ME
authors.lastname: Shaffrey
mesh_terms: D001918:Brachytherapy / Q000379:methods; D001931:Brain Mapping / Q000379:methods; D001932:Brain Neoplasms / Q000188:drug therapy / Q000473:pathology / Q000601:surgery*; D017024:Chemotherapy, Adjuvant; D003131:Combined Modality Therapy; D005910:Glioma / Q000188:drug therapy / Q000473:pathology / Q000601:surgery*; D006801:Humans; D007430:Intraoperative Care; D008279:Magnetic Resonance Imaging; D015225:Magnetoencephalography; D009367:Neoplasm Staging; D019635:Neurosurgical Procedures / Q000379:methods*; D011300:Preoperative Care