title: Cancer clinical trials: development and implementation.
abstract: Although much of the current standard of care in veterinary oncology is based on retrospective studies or transference from the human literature, a new era of clinical trial awareness brought on by new consortia and cooperative investigative groups is beginning to change this limitation. The use of controlled, randomized, blind multicenter trials testing new cytotoxics and cytostatic agents is now becoming the norm rather than the exception. Ultimately, advanced clinical trial design applied to companion animal populations should advance veterinary-based practice and inform future human clinical trials that may follow.
authors.affiliation: Center for Clinical Trials and Research, School of Veterinary Medicine, University of Wisconsin-Madison, 2015 Linden Drive, Madison, WI 53706, USA. vaild@svm.vetmed.wisc.edu
authors.forename: David M
authors.initials: DM
authors.lastname: Vail
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D002986:Clinical Trials as Topic / Q000662:veterinary*; D009369:Neoplasms / Q000188:drug therapy*; D012107:Research Design
chemical_list: D000970:Antineoplastic Agents