title: Circumferential resection margin assessment on MRI of rectal cancer.
abstract: The circumferential resection margin (CRM) has been shown to be a good predictor of the outcome of the total mesorectal resection surgical procedure in colorectal cancer. The CRM is increasingly used as a key parameter in patient management for colorectal cancer. It has been proposed that CRM can be estimated from MRI volumes taken pre-operatively; but to date the estimation of CRM is slice-based, hence two dimensional. We report a fully three-dimensional method to estimate the CRM, taking account of the MRI slice orientation used during the acquisition process. Prior to this, we segment the rectum and mesorectum. Preliminary results are reported for 10 patient cases, and a further large set are currently being analysed and results will be available at the time of the conference.
authors.affiliation: Dept. of Eng. Sci., Oxford Univ., UK. styliani@robots.ox.ac.uk
authors.forename: Styliani
authors.initials: S
authors.lastname: Petroudi
authors.forename: Gina
authors.initials: G
authors.lastname: Brown
authors.forename: Sarah
authors.initials: S
authors.lastname: Bond
authors.forename: Michael
authors.initials: M
authors.lastname: Brady
mesh_terms: D000465:Algorithms; D015179:Colorectal Neoplasms / Q000175:diagnosis / Q000628:therapy; D006801:Humans; D007090:Image Interpretation, Computer-Assisted / Q000295:instrumentation / Q000379:methods; D021621:Imaging, Three-Dimensional; D008279:Magnetic Resonance Imaging / Q000295:instrumentation* / Q000379:methods*; D008953:Models, Anatomic; D015233:Models, Statistical; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis; D012004:Rectal Neoplasms / Q000175:diagnosis* / Q000601:surgery*; D015203:Reproducibility of Results; D016896:Treatment Outcome