Fatal coinfection with Legionella pneumophila serogroup 8 and Aspergillus fumigatus.
Legionella pneumophila is an important cause of community-acquired and nosocomial pneumonia. We report on a patient who simultaneously developed L. pneumophila serogroup 8 pneumonia and Aspergillus fumigatus lung abscesses. Despite appropriate treatments, Aspergillus disease progressed with metastasis. Coinfections caused by L. pneumophila and A. fumigatus remain exceptional. In apparently immunocompetent patients, corticosteroid therapy is a key risk factor for aspergillosis.
Guillouzouic
Aurélie
A
Laboratoire de Bactériologie-Hygiène, CHU de Nantes, 44093 Nantes Cedex, France.
Bemer
Pascale
P
Gay-Andrieu
Françoise
F
Bretonnière
Cédric
C
Lepelletier
Didier
D
Mahé
Pierre-Joachim
PJ
Villers
Daniel
D
Jarraud
Sophie
S
Reynaud
Alain
A
Corvec
Stéphane
S
D001228:Aspergillosis / Q000150:complications* / Q000188:drug therapy; D001232:Aspergillus fumigatus / Q000302:isolation & purification*; D017809:Fatal Outcome; D006801:Humans; D016952:Legionella pneumophila / Q000145:classification / Q000302:isolation & purification*; D007877:Legionnaires' Disease / Q000150:complications* / Q000188:drug therapy; D008169:Lung Abscess / Q000382:microbiology; D008297:Male; D008875:Middle Aged; D013902:Radiography, Thoracic; D014057:Tomography, X-Ray Computed