Development of a multi-channel system for intrinsic cardiac neural recording.
Recent clinical evidence suggests that abnormal neural input can contribute to the onset perpetuation of atrial arrhythmias, such that neural elements have become potential targets for ablation. A better understanding of the influence of the cardiac autonomous nervous system is required to improve therapy. We have developed a multi-channel system to record neural activity simultaneously at different intra and pericardiac locations. The paper presents the specific requirements to be met for recording neuronal extracellular potentials in these repertoires of neurons and the solutions that were adopted.
Dubeau
Simon
S
Department of Physiology and Institute of Biomedical Engineering, University of Montreal, Montreal, Canada. simon.dubeau@umontreal.ca
Vinet
Alain
A
Richer
L P
LP
Guardo
Robert
R
Armour
J A
JA
D000200:Action Potentials; D000818:Animals; D001145:Arrhythmias, Cardiac / Q000503:physiopathology*; D019719:Diagnostic Equipment; D004285:Dogs; D004867:Equipment Design; D006329:Heart Conduction System / Q000503:physiopathology*