title: Metachronous metastasis to the penis from a rectal adenocarcinoma.
abstract: Penile metastases arise most frequently from genitourinary cancers, but can also arise from tumors of the large bowel; other primary sites are extremely uncommon. We report the case of a 59-year-old patient with 2 penile metastases from a rectal adenocarcinoma, which was discovered 26 years after abdominoperineal resection. Penile biopsy was carried out and established the metastatic nature. The patient underwent palliative chemotherapy treatment with cetuximab/irinotecan. All previously reported cases of penile metastasis from the rectum are reviewed. Regardless of the treatment options, the prognosis of such metastasis remains poor.
authors.affiliation: Department of Urology, Centre Hospitalier Saint Malo, Saint Malo, France. sabeurketata@yahoo.fr
authors.forename: Sabeur
authors.initials: S
authors.lastname: Ketata
authors.forename: Jean Loup
authors.initials: JL
authors.lastname: Boulaire
authors.forename: Benamar
authors.initials: B
authors.lastname: Soulimane
authors.forename: Alain
authors.initials: A
authors.lastname: Bargain
mesh_terms: D000230:Adenocarcinoma / Q000188:drug therapy / Q000473:pathology / Q000556:secondary*; D000911:Antibodies, Monoclonal / Q000008:administration & dosage; D061067:Antibodies, Monoclonal, Humanized; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002166:Camptothecin / Q000008:administration & dosage / Q000031:analogs & derivatives; D000068818:Cetuximab; D006801:Humans; D007150:Immunohistochemistry; D000077146:Irinotecan; D008297:Male; D008875:Middle Aged; D010166:Palliative Care; D010412:Penile Neoplasms / Q000188:drug therapy / Q000473:pathology / Q000556:secondary*; D011379:Prognosis; D012004:Rectal Neoplasms / Q000473:pathology*
chemical_list: D000911:Antibodies, Monoclonal; D061067:Antibodies, Monoclonal, Humanized; D000077146:Irinotecan; D000068818:Cetuximab; D002166:Camptothecin