Effect of calcium ions on the density of lecithin and its effective molecular volume in lecithin-water dispersions.
As the packing structure of lipid molecules in the liposomes will vary in the presence of ions, it is expected that the density of lipid and the effective volume of lipid molecules in the dispersions will also vary, albeit minutely. Density measurements of lipid-water dispersions with the addition of Ca(2+) ions were determined accurately. The effect of Ca(2+) ions on the molecular packing structure of the liposomes was elucidated from the results obtained. The results for the density of the lecithin in the dispersions with and without the addition of Ca(2+) ions are, respectively, 1.0782 and 1.0579 g cm(-3) at 25 degrees C; and 1.0048 and 0.9961 g cm(-3) at 50 degrees C. The average values of the effective molecular volume of lecithin in the dispersions with and without the addition of Ca(2+) ions are, respectively, 1.131E-21 and 1.152E-21 cm(3) at 25 degrees C; and 1.213E-21 and 1.224E-21 cm(3) at 50 degrees C.
Yeap
Pei Koon
PK
School of Physics, Universiti Sains Malaysia, 11800 Penang, Malaysia.
Lim
Koon Ong
KO
Chong
Chon Sing
CS
Teng
Tjoon Tow
TT
D002122:Calcium Chloride / Q000494:pharmacology*; D003720:Densitometry; D054709:Lecithins / Q000737:chemistry*; D008081:Liposomes / Q000737:chemistry*; D009391:Nephelometry and Turbidimetry; D013696:Temperature; D014867:Water / Q000737:chemistry
D054709:Lecithins; D008081:Liposomes; D014867:Water; D002122:Calcium Chloride