title: [Prevalence of metabolic syndrome using NCEP-ATPIII and IDF definitions in Brazilian individuals].
abstract: OBJECTIVE
  To analyze the biochemical profile and to characterize metabolic syndrome (MS) in patients with cardiologic medical assistance using NCEP-ATPIII and IDF definitions.
  
  
  METHODS
  Two hundred patients and 140 controls were studied, considering total cholesterol (TC), HDL-cholesterol (HDLc), LDL-cholesterol (LDLc), VLDL-cholesterol (VLDLc), triglycerides (TG), fasting glycemia, abdominal waist and hypertension. Significance level was defined as P<0.05.
  
  
  RESULTS
  Patients showed increased glycemia levels (103+/-31.4 mg/dL) and reduced HDLc levels (48+/-13.4 mg/dL) when compared to controls (88+/-29.7 mg/dL, P<0.0001 and 53+/-15.9 mg/dL, P=0.0075; respectively). Male controls 31-50 years old showed increased TC levels (215+/-40.4 mg/dL), LDL-cholesterol (134+/-34 mg/dL), VLDL-cholesterol (30+/-11.8 mg/dL) and TG (150+/-59.4 mg/dL) when compared to women (185+/-38.2 mg/dL, P=0.0137; 111+/-35.8 mg/dL; P=0.0324; 19+/-9.7 mg/dL; P=0.0009; 93+/-49 mg/dL, P=0.0010; respectively). Women over 50 years of age showed increased TC concentrations (216+/-35.9 mg/dL), HDL-cholesterol (54+/-12.8 mg/dL) and LDL-cholesterol (138+/-30.8 mg/dL) when compared to men (190+/-44.7 mg/dL, P=0.0103; 47+/-14.5 mg/dL, P=0.0229; 119+/-33.3 mg/dL; P=0.0176; respectively). NCEP-ATPIII and IDF definitions had characterized MS in 35.5% and 46% of patients, respectively, bolding glycemia, TG and hypertension.
  
  
  CONCLUSIONS
  Elevated glycemia levels and reduced HDLc levels were detected in patients. Altered lipid profile observed in men 31-50 years old signals higher risk for cardiovascular diseases in young adults, while a similar profile in aged women can reflect hormonal physiological changes. Both definitions for MS diagnosis discriminate patients from controls, especially IDF, sometimes with lower capacity to determine high risk for cardiovascular complications. The high prevalence of MS in patients, even with cardiologic medical assistance, suggests predisposition for cardiovascular manifestations in Brazilian individuals.
authors.affiliation: Instituto Domingo Braile de Cardiologia, Faculdade de Medicina de São José do Rio Preto, SP, Brasil. naka_med@yahoo.com
authors.forename: Marcelo Arruda
authors.initials: MA
authors.lastname: Nakazone
authors.forename: Anielli
authors.initials: A
authors.lastname: Pinheiro
authors.forename: Maria Christiane Valéria Braga
authors.initials: MC
authors.lastname: Braile
authors.forename: Marcela Augusta de Souza
authors.initials: MA
authors.lastname: Pinhel
authors.forename: Gisele Firmino
authors.initials: GF
authors.lastname: de Sousa
authors.forename: Sidney
authors.initials: S
authors.lastname: Pinheiro
authors.forename: Antônio Carlos
authors.initials: AC
authors.lastname: Brandão
authors.forename: Juan Carlos Yugar
authors.initials: JC
authors.lastname: Toledo
authors.forename: Domingo Marcolino
authors.initials: DM
authors.lastname: Braile
authors.forename: Dorotéia Rossi Silva
authors.initials: DR
authors.lastname: Souza
mesh_terms: D000328:Adult; D015415:Biomarkers / Q000097:blood; D001786:Blood Glucose; D001938:Brazil / Q000453:epidemiology; D002318:Cardiovascular Diseases / Q000209:etiology*; D016022:Case-Control Studies; D002784:Cholesterol / Q000097:blood*; D008076:Cholesterol, HDL / Q000097:blood; D008078:Cholesterol, LDL / Q000097:blood; D005260:Female; D006801:Humans; D006973:Hypertension / Q000175:diagnosis / Q000209:etiology; D008055:Lipids / Q000097:blood*; D008297:Male; D024821:Metabolic Syndrome / Q000175:diagnosis / Q000453:epidemiology*; D008875:Middle Aged; D015995:Prevalence; D012307:Risk Factors; D017678:Sex Distribution; D012737:Sex Factors; D014280:Triglycerides / Q000097:blood; D049629:Waist-Hip Ratio
chemical_list: D015415:Biomarkers; D001786:Blood Glucose; D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D008055:Lipids; D014280:Triglycerides; D002784:Cholesterol