title: Diagnosing active inflammation in the SAPHO syndrome using 18FDG-PET/CT in suspected metastatic vertebral bone tumors.
abstract: The vertebral spine is frequently affected by the SAPHO (synovitis, acne, pustulosis, hyperostosis, and osteitis) syndrome. We report the collective imaging findings of hybrid F-18 fluorodeoxyglucose-positron emission tomography/computed tomography (18FDG-PET/CT), as well as bone scans and magnetic resonance imaging, in a patient who had suspected metastatic vertebral bone tumors. 18FDG-PET/CT can be utilized to exclude metastatic vertebral tumors, as well as identifying stable lesions, by demonstrating active inflammatory lesions with accurate anatomic localization through the convergence of the functional information from 18FDG uptake with the anatomic information of CT.
authors.affiliation: Department of Nuclear Medicine and Radiology, Institute of Development, Aging and Cancer, Tohoku University, 4-1 Seiryo-machi, Aoba-ku, and Department of Orthopaedic Surgery, Tohoku University Hospital, Sendai, 980-8575, Japan. kenta@idac.tohoku.ac.jp
authors.forename: Kentaro
authors.initials: K
authors.lastname: Inoue
authors.forename: Tatsuo
authors.initials: T
authors.lastname: Yamaguchi
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Ozawa
authors.forename: Ken
authors.initials: K
authors.lastname: Okada
authors.forename: Yasuyuki
authors.initials: Y
authors.lastname: Taki
authors.forename: Ryoi
authors.initials: R
authors.lastname: Goto
authors.forename: Shigeo
authors.initials: S
authors.lastname: Kinomura
authors.forename: Tomohiro
authors.initials: T
authors.lastname: Kaneta
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Fukuda
mesh_terms: D020083:Acquired Hyperostosis Syndrome / Q000175:diagnosis*; D000368:Aged; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D010000:Osteitis / Q000175:diagnosis*; D049268:Positron-Emission Tomography / Q000379:methods*; D019275:Radiopharmaceuticals; D013125:Spinal Neoplasms / Q000175:diagnosis* / Q000556:secondary*; D014057:Tomography, X-Ray Computed / Q000379:methods*
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18