title: [Cytoxic activities of total alkaloids isolated from fructus broussonetiae in vitro].
abstract: OBJECTIVE
  To observe the cytoxic activities of total alkaloids isolated from Fructus Broussonetiae on the growth inhibition in five carcinoma cell lines.
  
  
  METHODS
  The growth inhibition was analyzed by MTT, Cell colony in the Hela, BEL-7402, A375, SMM1990, Saos-2 cell lines.
  
  
  RESULTS
  The growth of all tumor cells were inhibited by total alkaloids isolated from Fructus Broussonetiae.
  
  
  CONCLUSIONS
  The results show that total alkaloids isolated from Fructus Broussonetiae possess the role of antitumors in cell culture.
authors.affiliation: Department of Pharmacy, 180th Hospital of PLA, Quanzhou 362000, China.
authors.forename: Su-qiu
authors.initials: SQ
authors.lastname: Pang
authors.forename: Guo-quan
authors.initials: GQ
authors.lastname: Wang
authors.forename: Bao-kang
authors.initials: BK
authors.lastname: Huang
authors.forename: Lu-ping
authors.initials: LP
authors.lastname: Qin
mesh_terms: D000470:Alkaloids / Q000302:isolation & purification / Q000494:pharmacology*; D000972:Antineoplastic Agents, Phytogenic / Q000494:pharmacology*; D031623:Broussonetia / Q000737:chemistry*; D045744:Cell Line, Tumor; D049109:Cell Proliferation / Q000187:drug effects*; D004305:Dose-Response Relationship, Drug; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification / Q000494:pharmacology; D006367:HeLa Cells; D006801:Humans; D010946:Plants, Medicinal / Q000737:chemistry
chemical_list: D000470:Alkaloids; D000972:Antineoplastic Agents, Phytogenic; D004365:Drugs, Chinese Herbal