title: A polyacetylene compound from herbal medicine regulates genes associated with thrombosis in endothelial cells.
abstract: From Toki-shakuyaku-san, an herbal formulation for 'cleansing stagnated blood,' a key gene regulatory compound was purified and identified through a screening based on DNA microarray and real-time PCR.
authors.affiliation: Department of Chemistry, Hunter College of CUNY, 695 Park Avenue, New York, NY 10065, USA.
authors.forename: Akira
authors.initials: A
authors.lastname: Kawamura
authors.forename: Maria
authors.initials: M
authors.lastname: Iacovidou
authors.forename: Anna
authors.initials: A
authors.lastname: Takaoka
authors.forename: Clifford E
authors.initials: CE
authors.lastname: Soll
authors.forename: Michael
authors.initials: M
authors.lastname: Blumenstein
mesh_terms: D002478:Cells, Cultured; D042783:Endothelial Cells / Q000187:drug effects* / Q000378:metabolism*; D005786:Gene Expression Regulation / Q000187:drug effects*; D029001:Herbal Medicine; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D010936:Plant Extracts / Q000737:chemistry / Q000494:pharmacology; D053279:Polyynes / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology*; D013927:Thrombosis / Q000378:metabolism*
chemical_list: D010936:Plant Extracts; D053279:Polyynes