Stress, social support, and delayed skin barrier recovery.
OBJECTIVE
To examine the effect of a brief laboratory stressor and social support before the stressor on cardiovascular and cortisol responses, and skin barrier recovery after skin disruption.


METHODS
Eighty-five healthy participants (mean age 22.9 +/- 4.4 years) underwent a "tape-stripping" procedure that disrupts normal skin barrier function, and were randomly assigned to a No Stress (reading task), Stress (Trier Social Stress Test), or Stress + Social Support condition (support from a confederate before the stressor). Skin barrier recovery was assessed by measuring transepidermal water loss from up to 2 hours after skin disruption.


RESULTS
Compared with the No Stress condition, the stressor delayed skin barrier recovery by 10% at 2 hours after skin disruption (effect size, r = .29), and increased anxiety (r = .24), negative affect (r = .22), cardiovascular activity (r values from .4-.6), and among male participants, cortisol levels (r = .40). Social support did not influence psychological or physiological responses or skin barrier recovery. Larger physiological responses to the tasks did not predict slower skin barrier recovery. Instead, larger systolic blood pressure responses predicted faster skin barrier recovery (r = .26).


CONCLUSIONS
This study replicated the effects of short-term laboratory stressors on skin barrier recovery, further establishing the relevance of skin barrier recovery for future research. The support manipulation did not influence physiological responses or skin barrier recovery, suggesting that future research on social support, physiology, and objective health outcomes should focus on naturalistic social interactions, relationships, and stressors.
Robles
Theodore F
TF
UCLA Department of Psychology, Box 951563, 1285 Franz Hall, Los Angeles, CA 90095-1563, USA. robles@psych.ucla.edu
D000293:Adolescent; D000328:Adult; D000339:Affect; D001007:Anxiety; D001794:Blood Pressure; D005260:Female; D006339:Heart Rate; D006801:Humans; D006854:Hydrocortisone / Q000378:metabolism; D008297:Male; D012463:Saliva / Q000378:metabolism; D012867:Skin / Q000293:injuries; D012944:Social Support; D013315:Stress, Psychological / Q000503:physiopathology*; D014945:Wound Healing
D006854:Hydrocortisone