A novel use for capillary channel fibers: enhanced engineered tissue systems.
Capillary channel fibers (CCF) were selected for use in tissue engineering systems, due to their fluid wicking and cell guiding abilities. A study was conducted, comparing cell adhesion to CCF and mesh to traditional systems with fibers of round cross sectional area. A series of biochemical assays was conducted; the results indicated enhanced cellular attachment to the CCF based systems. Ongoing studies are being conducted to determine the rate of liquid diffusion within CCF reinforced tissue engineered composite systems.
Burg
Karen J L
KJ
Clemson University, SC 29634, USA. kburg@clemson.edu
Brunson
Douglas
D
D016475:3T3 Cells; D000818:Animals; D001672:Biocompatible Materials / Q000737:chemistry*; D002197:Capillary Action; D002448:Cell Adhesion / Q000502:physiology*; D018929:Cell Culture Techniques / Q000295:instrumentation / Q000379:methods*; D002470:Cell Survival / Q000502:physiology*; D008422:Materials Testing; D051379:Mice; D010316:Particle Size; D011091:Polyesters / Q000737:chemistry*; D023822:Tissue Engineering / Q000295:instrumentation / Q000379:methods*
D001672:Biocompatible Materials; D011091:Polyesters; C033616:poly(lactide)