None of polymorphism of ovine fecundity major genes FecB and FecX was tested in goat.
The polymorphism of mutation Q249R in BMPR-IB gene (FecB) and loci FecX(I), FecX(H), FecX(G), FecX(B) in BMP15 gene was analyzed by forced PCR-RFLP method in 550 individuals from 6 flocks or breeds of goats with litter size varied from 1.4 to 2.7 including Boer (209), Haimen (128), second generation of Boer goat crossed with Huanghuai goat (82), Huanghuai (71), Nubi (37) and Matou (23) goat. None of mutations was detected in these goat breeds and their crossbreed. These results suggest that fecundity of goat is not linked to the same loci in BMPR-IB and BMP15 as sheep. Therefore, it is necessary to seek for other genes or loci in order to develop marker assistance selection techniques and study the prolific mechanism of the goat.
Hua
Guo-Hua
GH
College of Animal Science and Technology, Huazhong Agricultural University, Wuhan 430070, China.
Chen
Shi-Lin
SL
Ai
Jun-Tao
JT
Yang
Li-Guo
LG
D000818:Animals; D000831:Animals, Newborn; D055430:Bone Morphogenetic Protein 15 / Q000235:genetics*; D052005:Bone Morphogenetic Protein Receptors, Type I / Q000235:genetics*; D004247:DNA / Q000737:chemistry / Q000235:genetics; D004591:Electrophoresis, Polyacrylamide Gel / Q000662:veterinary; D005260:Female; D005298:Fertility / Q000235:genetics*; D006041:Goats / Q000235:genetics*; D008098:Litter Size / Q000235:genetics; D016133:Polymerase Chain Reaction / Q000662:veterinary; D012150:Polymorphism, Restriction Fragment Length; D020641:Polymorphism, Single Nucleotide
D055430:Bone Morphogenetic Protein 15; D004247:DNA; D052005:Bone Morphogenetic Protein Receptors, Type I