[Human seminal plasma allergy type I].
Human seminal plasma allergy (HSPA) is a rare allergic reaction to specific protein fractions of seminal plasma, whereof PSA seems to be a relevant allergen. Predominantly Type I-immunoreactions can occur. The main symptoms are localized and generalized urticaria and sometimes anaphylactic symptoms. The diagnosis is based on history, skin tests and on the determination of specific IgE-levels for (un)fractionated seminal plasma. Here we report a patient with recurrent episodes of generalized urticaria after unprotected sexual intercourse and positive prick-test-reaction on seminal plasma.
Winter
U M
UM
Klinik für Dermatologie, Venerologie und Allergologie, Universitätsklinikum Leipzig AöR, Philipp-Rosenthal-Str. 23-25, 04103 Leipzig. ulrike.winter@medizin.uni-leipzig.de
Harth
W
W
Treudler
R
R
Simon
J C
JC
D000328:Adult; D017280:Condoms; D003888:Desensitization, Immunologic; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D006969:Hypersensitivity, Immediate / Q000175:diagnosis / Q000209:etiology* / Q000276:immunology / Q000628:therapy; D007428:Intradermal Tests; D012661:Semen / Q000276:immunology*; D014581:Urticaria / Q000175:diagnosis / Q000209:etiology* / Q000276:immunology / Q000628:therapy; D014847:Vulvitis / Q000175:diagnosis / Q000209:etiology* / Q000276:immunology / Q000628:therapy