[Inversion of the sequence of surgery after neoadjuvant chemotherapy for synchronous liver metastases from colorectal cancer].
In some patients with colorectal cancer and synchronous liver metastases, chemotherapy and current combinations of chemotherapy allow the size of these metastases to be reduced so that they can be surgically resected. However, in many patients, the initial systematic treatment of the primary tumor is associated with growth of the metastases (which predict the patient's life expectancy). This metastatic growth contraindicates surgical treatment that might otherwise be curative. We report the case of a patient with advanced recto-colonic cancer, which responded well to chemotherapy given as neoadjuvant treatment prior to surgery, in which the hepatic metastases were resected before excision of the primary tumor.
Marín-Hargreaves
Guillermo
G
Servicio de Cirugía General y Digestiva, Hospital de la Santa Creu i de Sant Pau, Barcelona, España. gmarin@hsp.santpau.es
Artigas
Vicente
V
González
José A
JA
Martínez
Carmen
C
Marcuello
Eugenio
E
Trías-Folch
Manuel
M
D017024:Chemotherapy, Adjuvant / Q000379:methods*; D015179:Colorectal Neoplasms / Q000188:drug therapy* / Q000473:pathology* / Q000601:surgery*; D003131:Combined Modality Therapy; D006801:Humans; D008113:Liver Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary* / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000000981:diagnostic imaging / Q000601:surgery; D013514:Surgical Procedures, Operative / Q000379:methods*; D013997:Time Factors; D014057:Tomography, X-Ray Computed