title: [Clinical and pathological characteristics of patients with glomerular hematuria as the major manifestation].
abstract: OBJECTIVE
  To compare the clinical and pathological characteristics between patients with and without glomerular hematuria.
  
  
  METHODS
  Totally 310 patients with isolated microscopic hematuria and 24-hour urinary protein <0.5 g were enrolled in this study, who were free of renal calculi, infections, or tumors. These patients were divided into glomerular hematuria group and non-glomerular hematuria group according examination by phase-contrast microscope, and their clinicopathological data were retrospectively analyzed.
  
  
  RESULTS
  Of the 209 patients identified to have glomerular hematuria, 46.41% had IgA nephropathy, 22.49% had small glomerular lesions, and 14.35% had non-IgA mesangioproliferative glomerulonephritis. In the patients with non-glomerular hematuria, 65.34% had IgA nephropathy, 21.78% had non-IgA mesangioproliferative glomerulonephritis, and 8.91% had small glomerular lesions. No significant differences were found in the patients' gender, age, course of disease or hypertension between the two groups (P>0.05), but renal insufficiency was more common in patients with glomerular hematuria.
  
  
  CONCLUSIONS
  IgA nephropathy is still the most frequent pathological finding in patients with hematuria, and even in non-glomerular hematuria patients severe renal pathological changes can be common.
authors.affiliation: Department of Nephrology, Second Affiliated Hospital, Sun Yat-sen University, Guangzhou 510120, China. wanxia@medmail.com.cn
authors.forename: Xia
authors.initials: X
authors.lastname: Wan
authors.forename: Yi-Min
authors.initials: YM
authors.lastname: Zhang
authors.forename: Wan
authors.initials: W
authors.lastname: Liu
authors.forename: Hu-Hui
authors.initials: HH
authors.lastname: Huang
authors.forename: Jin-Gao
authors.initials: JG
authors.lastname: Li
mesh_terms: D000328:Adult; D005260:Female; D005922:Glomerulonephritis, IGA / Q000473:pathology; D006417:Hematuria / Q000473:pathology*; D006801:Humans; D007678:Kidney Glomerulus / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D055815:Young Adult