title: Early life programming of energy balance.
abstract: Obesity prevalence is increasing worldwide, leading to increased morbidity, mortality and health care costs due to its role as a key risk factor in many diseases. Early life growth and nutrition has been implicated in determining susceptibility to obesity in both childhood and adulthood; however, the mechanisms underlying this link are poorly understood. A variety of animal models have been established to try and uncover the developmental programming effects of maternal early life nutrition on energy balance regulation and the mechanisms behind them.
authors.affiliation: Department of Clinical Biochemistry, University of Cambridge, Level 4, Box 232, Addenbrooke's Hospital, Hills Road, Cambridge CB2 2QR, U.K. rlc34@cam.ac.uk
authors.forename: R L
authors.initials: RL
authors.lastname: Cripps
authors.forename: Z A
authors.initials: ZA
authors.lastname: Archer
authors.forename: J G
authors.initials: JG
authors.lastname: Mercer
authors.forename: S E
authors.initials: SE
authors.lastname: Ozanne
mesh_terms: D000818:Animals; D004734:Energy Metabolism; D006801:Humans; D023421:Models, Animal