Effects of ethanolic extract of Syzygium cumini (Linn) seed powder on pancreatic islets of alloxan diabetic rats.
The ethanolic extract of seeds of S. cumini increased body weight and decreased blood sugar level in alloxan diabetic albino rats. Level of significance for decrease in blood sugar after feeding alcoholic extract of S. cumini seeds in various doses was highly significant. The extract feeding showed definite improvement in the histopathology of islets. The most important finding is that the blood sugar level, which once dropped to normal levels after extract feeding was not elevated when extract feeding was discontinued for 15 days.
Singh
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Environmental Endocrinology and Biomedical Research Unit, Department of Zoology, Meerut College, Meerut 250 003, India. n27singh@yahoo.com
Gupta
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M
D000496:Alloxan / Q000494:pharmacology; D000818:Animals; D001786:Blood Glucose / Q000378:metabolism; D001835:Body Weight / Q000187:drug effects; D003921:Diabetes Mellitus, Experimental / Q000139:chemically induced / Q000378:metabolism / Q000473:pathology*; D000431:Ethanol / Q000737:chemistry*; D007515:Islets of Langerhans / Q000187:drug effects* / Q000378:metabolism; D008297:Male; D010936:Plant Extracts / Q000737:chemistry / Q000494:pharmacology*; D011208:Powders; D051381:Rats; D017208:Rats, Wistar; D012639:Seeds / Q000737:chemistry*; D027842:Syzygium / Q000737:chemistry*
D001786:Blood Glucose; D010936:Plant Extracts; D011208:Powders; D000431:Ethanol; D000496:Alloxan