[Cytoxic activities of total alkaloids isolated from fructus broussonetiae in vitro].
OBJECTIVE
To observe the cytoxic activities of total alkaloids isolated from Fructus Broussonetiae on the growth inhibition in five carcinoma cell lines.


METHODS
The growth inhibition was analyzed by MTT, Cell colony in the Hela, BEL-7402, A375, SMM1990, Saos-2 cell lines.


RESULTS
The growth of all tumor cells were inhibited by total alkaloids isolated from Fructus Broussonetiae.


CONCLUSIONS
The results show that total alkaloids isolated from Fructus Broussonetiae possess the role of antitumors in cell culture.
Pang
Su-qiu
SQ
Department of Pharmacy, 180th Hospital of PLA, Quanzhou 362000, China.
Wang
Guo-quan
GQ
Huang
Bao-kang
BK
Qin
Lu-ping
LP
D000470:Alkaloids / Q000302:isolation & purification / Q000494:pharmacology*; D000972:Antineoplastic Agents, Phytogenic / Q000494:pharmacology*; D031623:Broussonetia / Q000737:chemistry*; D045744:Cell Line, Tumor; D049109:Cell Proliferation / Q000187:drug effects*; D004305:Dose-Response Relationship, Drug; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification / Q000494:pharmacology; D006367:HeLa Cells; D006801:Humans; D010946:Plants, Medicinal / Q000737:chemistry
D000470:Alkaloids; D000972:Antineoplastic Agents, Phytogenic; D004365:Drugs, Chinese Herbal