title: Acute aortic dissection.
abstract: Acute aortic dissection is an uncommon but potentially catastrophic illness with high mortality. Significant advances in the understanding, diagnosis, and management have been made since the first reported case of aortic dissection 3 centuries ago. This comprehensive review discusses the pathophysiology, classification, clinical manifestations, early diagnosis, and management of this important cardiovascular emergency.
authors.affiliation: St. John Hospital and Medical Center, Detroit, MI 48236, USA. desikan.kamalakannan@stjohn.org
authors.forename: Desikan
authors.initials: D
authors.lastname: Kamalakannan
authors.forename: Howard S
authors.initials: HS
authors.lastname: Rosman
authors.forename: Kim A
authors.initials: KA
authors.lastname: Eagle
mesh_terms: D000208:Acute Disease; D000465:Algorithms; D000784:Aortic Dissection / Q000145:classification / Q000175:diagnosis* / Q000503:physiopathology / Q000628:therapy*; D001014:Aortic Aneurysm / Q000145:classification / Q000175:diagnosis* / Q000503:physiopathology / Q000628:therapy*; D015415:Biomarkers; D006348:Cardiac Surgical Procedures; D015984:Causality; D003952:Diagnostic Imaging; D006801:Humans; D010808:Physical Examination; D017410:Practice Guidelines as Topic
chemical_list: D015415:Biomarkers