Synthesis and biological activity of some novel derivatives of 4-amino-3-(D-galactopentitol-1-yl)-5-mercapto-1,2,4-triazole.
To discover new 1,2,4-triazole derivatives which may possess significant biological activities, we synthesized a series of novel 6-aryl-3-(D-galactopentitol-1-yl)-7H-1,2,4-triazolo[3,4-b][1,3,4]thiadiazines and 4-(arylmethylidene)amino-5-(D-galactopentitol-1-yl)-3-mercapto-4H-1,2,4-triazoles from 4-amino-3-(D-galactopentitol-1-yl)-5-mercapto-1,2,4-triazole. All the title compounds were characterized by elemental analysis, IR, 1H- and 13C-NMR. Plant growth-regulating activity tests showed that these compounds have remarkable effects on the growth of radish and wheat.
Jin
Jian-yu
JY
College of Education, Wenzhou University, Wenzhou 325035, PR China. jjy@wzu.edu.cn
Zhang
Li-xue
LX
Zhang
An-jiang
AJ
Lei
Xin-Xiang
XX
Zhu
Jiang-Hai
JH
D031224:Raphanus / Q000187:drug effects* / Q000254:growth & development; D013402:Sugar Alcohols / Q000494:pharmacology*; D014230:Triazoles / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D014908:Triticum / Q000187:drug effects* / Q000254:growth & development
C524600:4-amino-3-(galactopentitol-1-yl)-5-mercapto-1,2,4-triazole; D013402:Sugar Alcohols; D014230:Triazoles