title: Aerobic fitness and hand grip strength in Type 1 diabetes: relationship to glycaemic control and body composition.
abstract: OBJECTIVE
  To clarify the relationship of aerobic fitness and handgrip strength with glycaemic control (HbA1c), body composition and lipid profile in Type 1 diabetes.
  
  
  METHODS
  Aerobic capacity (Chester Step Test), handgrip strength and body composition (bioelectrical impedance) were measured in 141 patients with Type 1 diabetes.
  
  
  RESULTS
  Aerobic capacity correlated positively with HbA1c and lean body mass and negatively with body mass index and fat mass. Handgrip strength correlated positively with aerobic capacity and negatively with HbA1c and fat mass. In addition, there was a positive correlation between HbA1c and total cholesterol.
  
  
  CONCLUSIONS
  Patients with Type 1 diabetes who have good aerobic capacity have poorer glycaemic control. However, this was an observational study and the results must be interpreted with caution. Further investigation into how these patients manage blood glucose during exercise is required.
authors.affiliation: University Department of Diabetes and Endocrinology, Aintree University Hospitals NHS Foundation Trust, Liverpool, UK. maureen.wallymahmed@aintree.nhs.uk
authors.forename: M E
authors.initials: ME
authors.lastname: Wallymahmed
authors.forename: C
authors.initials: C
authors.lastname: Morgan
authors.forename: G V
authors.initials: GV
authors.lastname: Gill
authors.forename: I A
authors.initials: IA
authors.lastname: MacFarlane
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001786:Blood Glucose / Q000378:metabolism; D001823:Body Composition / Q000502:physiology; D003922:Diabetes Mellitus, Type 1 / Q000378:metabolism / Q000503:physiopathology* / Q000628:therapy; D003925:Diabetic Angiopathies / Q000378:metabolism / Q000503:physiopathology* / Q000628:therapy; D015444:Exercise / Q000502:physiology*; D005260:Female; D006442:Glycated Hemoglobin / Q000032:analysis; D018737:Hand Strength / Q000502:physiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012737:Sex Factors
chemical_list: D001786:Blood Glucose; D006442:Glycated Hemoglobin