title: Risk factors of arterial hypertension after renal transplantation.
abstract: Arterial hypertension often present after kidney transplantation is of multifactorial origin. The aim of this study was to determine the role of donor and recipient factors in the development of hypertension after renal transplantation. We retrospectively analyzed the data of 280 patients transplanted between 1985 and 2005, who still had functioning grafts at 1 year after transplantation. We recorded donor and recipient parameters. One hundred eighty-seven patients (66.8%) were hypertensive. Upon multivariate analysis of recipient factors, pretransplant hypertension (odds ratio) [OR]: 8.5, 95% confidence interval [CI]: 4.5 to 16.1); serum creatinine level > 130 micromol/L at 6 months (OR: 2.5, 95% CI: 1.3 to 4,7), male gender (OR: 2.02, 95% CI: 1.2 to 3.4), and chronic rejection (OR: 2.4, 95% CI: 1.2 to 4.7) were independent predisposing factors. Among donor factors, age was significantly associated with arterial hypertension upon univariate analysis. In conclusion, recipient factors, especially pretransplant hypertension, contribute to the disorder in renal transplant patients.
authors.affiliation: Department of Internal Medicine, Charles Nicolle Hospital, Boulevard du 9 Avril 1938, 1006 BS Tunis, Tunisia. soumaya.beji@rns.tn
authors.forename: S
authors.initials: S
authors.lastname: Béji
authors.forename: E
authors.initials: E
authors.lastname: Abderrahim
authors.forename: H
authors.initials: H
authors.lastname: Kaaroud
authors.forename: H
authors.initials: H
authors.lastname: Jebali
authors.forename: T
authors.initials: T
authors.lastname: Ben Abdallah
authors.forename: F
authors.initials: F
authors.lastname: El Younsi
authors.forename: F
authors.initials: F
authors.lastname: Ben Moussa
authors.forename: F
authors.initials: F
authors.lastname: Ben Hamida
authors.forename: A
authors.initials: A
authors.lastname: Sfaxi
authors.forename: M
authors.initials: M
authors.lastname: Blah
authors.forename: M
authors.initials: M
authors.lastname: Chebil
authors.forename: M
authors.initials: M
authors.lastname: Ayed
authors.forename: R
authors.initials: R
authors.lastname: Bardi
authors.forename: Y
authors.initials: Y
authors.lastname: Gorgi
authors.forename: A
authors.initials: A
authors.lastname: Kheder
mesh_terms: D000293:Adolescent; D000328:Adult; D015992:Body Mass Index; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D006973:Hypertension / Q000453:epidemiology*; D007166:Immunosuppressive Agents / Q000009:adverse effects / Q000627:therapeutic use; D016030:Kidney Transplantation / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000453:epidemiology*; D012307:Risk Factors
chemical_list: D007166:Immunosuppressive Agents