title: Characteristics of the formation of systems activity in the brain and autonomic functions in children in conditions of the European North (discussion paper).
abstract: Results obtained from complex medical-physiological investigations performed during 10 scientific expeditions in the Arkhangel'sk Region in 2003-2005 are presented. The effects of climatological-geographic, biogeochemical, and social conditions of the conditions obtaining in the Far North region of Russia on sexual maturation, formation of the structural-functional organization of the brain, autonomic functions, and immunological and biochemical status of schoolchildren were studied using state-of-the-art neurophysiological methods (computerized electroencephalography, computerized rheoencephalography, computerized electric dipole origin tomography, etc.), psychophysiological and psychometric methods (assessment of the state of cognitive and memory functions, Wechsler intellectual scale), along with biochemical assay of monoamine oxidase (MAO, the key enzyme in adrenergic neurotransmitter metabolism) and the liver enzyme butyrylcholinesterase (BuChE) and physicochemical analysis of the levels of macroelements and trace elements in the body.
authors.affiliation: Interinstitute Laboratory for Comparative Ecological-Physiological Studies, I. M. Sechenov Institute of Evolutionary Physiology and Biochemistry and North-East Scientific Center, Russian Academy of Sciences, St. Petersburg, Russia. soroko@iephb.ru
authors.forename: S I
authors.initials: SI
authors.lastname: Soroko
authors.forename: E A
authors.initials: EA
authors.lastname: Burykh
authors.forename: S S
authors.initials: SS
authors.lastname: Bekshaev
authors.forename: G V
authors.initials: GV
authors.lastname: Sidorenko
authors.forename: E G
authors.initials: EG
authors.lastname: Sergeeva
authors.forename: A E
authors.initials: AE
authors.lastname: Khovanskikh
authors.forename: B N
authors.initials: BN
authors.lastname: Kormilitsyn
authors.forename: S N
authors.initials: SN
authors.lastname: Moralev
authors.forename: O V
authors.initials: OV
authors.lastname: Yagodina
authors.forename: L K
authors.initials: LK
authors.lastname: Dobrodeeva
authors.forename: I A
authors.initials: IA
authors.lastname: Maksimova
authors.forename: O V
authors.initials: OV
authors.lastname: Protasova
mesh_terms: D000293:Adolescent; D000513:Alpha Rhythm; D001341:Autonomic Nervous System / Q000254:growth & development* / Q000502:physiology*; D001921:Brain / Q000254:growth & development* / Q000502:physiology*; D002091:Butyrylcholinesterase / Q000097:blood; D002560:Cerebrovascular Circulation; D002648:Child; D002664:Child Nutritional Physiological Phenomena; D002980:Climate; D003627:Data Interpretation, Statistical; D004569:Electroencephalography; D004594:Electrophysiology; D004798:Enzymes / Q000378:metabolism; D005260:Female; D006801:Humans; D007109:Immunity / Q000502:physiology; D008297:Male; D008995:Monoamine Oxidase / Q000097:blood; D009483:Neuropsychological Tests; D012424:Rural Population; D012426:Russia; D012931:Social Environment; D014131:Trace Elements / Q000378:metabolism; D014888:Wechsler Scales
chemical_list: D004798:Enzymes; D014131:Trace Elements; D008995:Monoamine Oxidase; D002091:Butyrylcholinesterase