Integrative analysis of intracranial pressure and R-R interval signals: a study of ICP B-wave using causal coherence.
Causal coherence analysis was applied to beat-to-beat mean intracranial pressure (ICP) and RR interval signals that were recorded from twelve normal pressure hydrocephalus patients. Data were organized into two groups including an ICP B-Wave group and a control baseline group. Maximal classic coherence between ICP and RR interval within [0.04-0.15] Hz was found to be significantly greater than zero for both B-wave and control groups. Causal coherence analysis further revealed that feedforward coherence due to RR interval's effect on ICP always exists for both B-wave and baseline ICP state while feedback coherence from ICP to RR interval was enhanced during the occurrence of B-wave.
Hu
Xiao
X
Division of Neuroscience, University of California, Los Angeles, USA.
Nenov
Valeriy
V
Bergsneider
Marvin
M
D000465:Algorithms; D001683:Biological Clocks / Q000502:physiology*; D003198:Computer Simulation; D003627:Data Interpretation, Statistical; D006339:Heart Rate / Q000502:physiology*; D006801:Humans; D007427:Intracranial Pressure / Q000502:physiology*; D008954:Models, Biological; D015233:Models, Statistical; D012044:Regression Analysis; D018511:Systems Integration