title: Novel arylhydrazone-conjugated gold nanoparticles with DNA-cleaving ability: the first DNA-nicking nanomaterial.
abstract: Arylhydrazones were linked onto gold nanoparticles through the poly(ethylene glycol) spacer to produce a new type of photoinduced DNA-cleaving nanomaterials with great potency.
authors.affiliation: Department of Chemistry, National Tsing Hua University, Hsinchu, Taiwan, ROC.
authors.forename: Ming-Hua
authors.initials: MH
authors.lastname: Hsu
authors.forename: Thainashmuthu
authors.initials: T
authors.lastname: Josephrajan
authors.forename: Chen-Sheng
authors.initials: CS
authors.lastname: Yeh
authors.forename: Dar-Bin
authors.initials: DB
authors.lastname: Shieh
authors.forename: Wu-Chou
authors.initials: WC
authors.lastname: Su
authors.forename: Jih Ru
authors.initials: JR
authors.lastname: Hwu
mesh_terms: D004247:DNA / Q000737:chemistry* / Q000378:metabolism; D053904:DNA Breaks, Single-Stranded; D006046:Gold / Q000737:chemistry*; D006834:Hydrazines / Q000737:chemistry*; D046529:Microscopy, Electron, Transmission; D015394:Molecular Structure; D053758:Nanoparticles / Q000737:chemistry* / Q000648:ultrastructure
chemical_list: D006834:Hydrazines; C029424:hydrazine; D006046:Gold; D004247:DNA