title: Cluster headache and intracranial aneurysm.
abstract: In the present study we describe the cases of two patients with cluster-like headache related to intracranial carotid artery aneurysm. One of these patients responded to verapamil prescription with headache resolution. In both cases the surgical clipping of the aneurysm resolved the cluster pain. These findings strongly suggest a pathophysiological link between the two conditions. The authors discuss the potential pathophysiological mechanisms underlying cluster-like headache due to intracranial carotid artery aneurysm.
authors.affiliation: Division of Neurology and Neurosurgery, Department of Neuropsychiatry, Federal University of Pernambuco, 50670-420, Recife, Pernambuco, Brazil. mmvalenca@yahoo.com.br
authors.forename: Marcelo Moraes
authors.initials: MM
authors.lastname: Valença
authors.forename: Luciana P A
authors.initials: LP
authors.lastname: Andrade-Valença
authors.forename: Carolina
authors.initials: C
authors.lastname: Martins
authors.forename: Maria
authors.initials: M
authors.lastname: de Fátima Vasco Aragão
authors.forename: Laécio Leitão
authors.initials: LL
authors.lastname: Batista
authors.forename: Mario Fernando Prieto
authors.initials: MF
authors.lastname: Peres
authors.forename: Wilson Farias
authors.initials: WF
authors.lastname: da Silva
mesh_terms: D000344:Afferent Pathways; D002121:Calcium Channel Blockers / Q000627:therapeutic use; D002343:Carotid Artery, Internal / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D002533:Cerebral Angiography; D003027:Cluster Headache / Q000175:diagnosis* / Q000209:etiology* / Q000503:physiopathology; D003937:Diagnosis, Differential; D006801:Humans; D002532:Intracranial Aneurysm / Q000150:complications* / Q000175:diagnosis* / Q000503:physiopathology; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D015878:Mydriasis / Q000209:etiology; D019635:Neurosurgical Procedures; D015840:Oculomotor Nerve Diseases / Q000175:diagnosis / Q000209:etiology* / Q000503:physiopathology; D013345:Subarachnoid Hemorrhage / Q000175:diagnosis / Q000209:etiology* / Q000601:surgery; D013525:Surgical Instruments; D016896:Treatment Outcome; D014656:Vascular Surgical Procedures; D014700:Verapamil / Q000627:therapeutic use
chemical_list: D002121:Calcium Channel Blockers; D014700:Verapamil