[Clinical and pathological characteristics of patients with glomerular hematuria as the major manifestation].
OBJECTIVE
To compare the clinical and pathological characteristics between patients with and without glomerular hematuria.


METHODS
Totally 310 patients with isolated microscopic hematuria and 24-hour urinary protein <0.5 g were enrolled in this study, who were free of renal calculi, infections, or tumors. These patients were divided into glomerular hematuria group and non-glomerular hematuria group according examination by phase-contrast microscope, and their clinicopathological data were retrospectively analyzed.


RESULTS
Of the 209 patients identified to have glomerular hematuria, 46.41% had IgA nephropathy, 22.49% had small glomerular lesions, and 14.35% had non-IgA mesangioproliferative glomerulonephritis. In the patients with non-glomerular hematuria, 65.34% had IgA nephropathy, 21.78% had non-IgA mesangioproliferative glomerulonephritis, and 8.91% had small glomerular lesions. No significant differences were found in the patients' gender, age, course of disease or hypertension between the two groups (P>0.05), but renal insufficiency was more common in patients with glomerular hematuria.


CONCLUSIONS
IgA nephropathy is still the most frequent pathological finding in patients with hematuria, and even in non-glomerular hematuria patients severe renal pathological changes can be common.
Wan
Xia
X
Department of Nephrology, Second Affiliated Hospital, Sun Yat-sen University, Guangzhou 510120, China. wanxia@medmail.com.cn
Zhang
Yi-Min
YM
Liu
Wan
W
Huang
Hu-Hui
HH
Li
Jin-Gao
JG
D000328:Adult; D005260:Female; D005922:Glomerulonephritis, IGA / Q000473:pathology; D006417:Hematuria / Q000473:pathology*; D006801:Humans; D007678:Kidney Glomerulus / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D055815:Young Adult