title: [Hypertension in pregnancy].
abstract: Hypertension affects approximately 10% of all pregnancies and may jeopardize maternal and fetal health. Chronic hypertension must be distinguished from pre-eclampsia, that can be associated with a bad outcome. An antihypertensive treatment is advocated when systolic blood pressure is > or = 160 mmHg or diastolic blood pressure is > or = 110 mmHg. Hospitalisation is mandatory if there is an associated proteinuria. Labetalol, nifedipine and methyldopa are the commonly used blood-pressure lowering drugs and they are considered safe during pregnancy. Angiotensin converting enzymes inhibitors and angiotensin II receptor blockers are contraindicated, even during the first trimester of pregnancy. The prescription of diuretics during pregnancy should be avoided.
authors.affiliation: Service de médecine communautaire, Département de médecine interne, HUG, 1211 Genève 14.
authors.forename: Laurence
authors.initials: L
authors.lastname: Clivaz Mariotti
authors.forename: Patrick
authors.initials: P
authors.lastname: Saudan
authors.forename: Ruth
authors.initials: R
authors.lastname: Landau Cahana
authors.forename: Antoinette
authors.initials: A
authors.lastname: Pechère-Bertschi
mesh_terms: D000959:Antihypertensive Agents / Q000627:therapeutic use; D005260:Female; D006801:Humans; D006973:Hypertension / Q000175:diagnosis* / Q000188:drug therapy / Q000503:physiopathology; D049590:Postpartum Period; D011247:Pregnancy
chemical_list: D000959:Antihypertensive Agents