title: A novel alkaloid from the fruits of Evodia officinalis.
abstract: Studies on the fruits of Evodia officinalis yielded a new quinazolinedione alkaloid, wuchuyuamide III (1), together with known alkaloids, goshuyuamide II (2), evodiamine and rutaecarpine. Their structures were elucidated by means of 1D and 2D NMR spectroscopic analysis. Wuchuyuamide III (1) and goshuyuamide II (2) showed modest cytotoxicity against HeLa and HT1080 cell lines.
authors.affiliation: School of Pharmacy, Shanghai Jiao Tong University, Shanghai, China. kimhz@sjtu.edu.cn
authors.forename: Hui-Zi
authors.initials: HZ
authors.lastname: Jin
authors.forename: Jing-Ling
authors.initials: JL
authors.lastname: Du
authors.forename: Wei-Dong
authors.initials: WD
authors.lastname: Zhang
authors.forename: Hai-Sheng
authors.initials: HS
authors.lastname: Chen
authors.forename: Jeong-Hyung
authors.initials: JH
authors.lastname: Lee
authors.forename: Jung-Joon
authors.initials: JJ
authors.lastname: Lee
mesh_terms: D000470:Alkaloids / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D045744:Cell Line, Tumor; D032086:Evodia / Q000737:chemistry*; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D013056:Spectrophotometry, Ultraviolet
chemical_list: D000470:Alkaloids