Negative pressure in pharyngo-oral cavity can treat lymphedema and related disorders.
With the finding of specific markers and growth factors for lymphatic vessels, more and more attentions were paid to research on lymphatic vascular system. But the treatment of lymphedema and related disorders is still difficult. Waldeyer's ring is the lymphoid tissues that form a ring around the opening of the throat including tonsils laterally, adenoids superiorly, and lingual tonsil at the base. We hypothesized that negative pressure in pharyngo-oral cavity can improve lymphatic system circulation by affect Waldeyer's ring. And this treatment is proved to be useful in the therapy of lymphedema and chyloperitoneum. So we came to the conclusion that negative pressure in pharyngo-oral cavity was helpful in the treatment of lymphedema and related disorders. But the mechanism of this treatment still need further study. The future of this field of research is very promising and may eventually lead to better treatment of lymphedema and related disorders.
Fang
Yunhai
Y
Shandong University, School of Medicine, Jinan 250012, China.
He
Yuxiang
Y
Liu
Zhiyu
Z
D016121:Brachiocephalic Veins / Q000473:pathology; D002915:Chylous Ascites / Q000378:metabolism; D006801:Humans; D008208:Lymphatic System; D042601:Lymphatic Vessels / Q000473:pathology; D008209:Lymphedema / Q000473:pathology* / Q000628:therapy*; D008221:Lymphoid Tissue / Q000473:pathology; D008954:Models, Biological; D008962:Models, Theoretical; D009055:Mouth / Q000473:pathology*; D009119:Muscle Contraction; D011312:Pressure; D013997:Time Factors; D016896:Treatment Outcome