Pulsed UV-light inactivation of poliovirus and adenovirus.
OBJECTIVE
To study the pulsed ultraviolet (UV) inactivation of poliovirus and adenovirus.


RESULTS
Viral suspensions of 2 ml volume were exposed to varying numbers of polychromatic light pulses emitted from a xenon flashlamp. Ten pulses produced an approximately 4 log(10) reduction in poliovirus titre, and no infectious poliovirus remained after 25 pulses. With adenovirus, 10 pulses resulted in an approximately 1 log(10) reduction in infectivity. Adenovirus required 100 pulses to produce an approximately 3 log(10) reduction in infectivity, and 200 pulses to produce a greater than 4 log(10) reduction.


CONCLUSIONS
Adenovirus was more resistant to pulsed UV treatment than poliovirus although both viruses showed susceptibility to the treatment.


CONCLUSIONS
Pulsed UV-light treatment proved successful in the inactivation of poliovirus and adenovirus, and represents an alternative to continuous-wave UV treatment.
Lamont
Y
Y
The Robertson Trust Laboratory for Electronic Sterilisation Technologies, University of Strathclyde, Royal College, Glasgow, UK.
Rzezutka
A
A
Anderson
J G
JG
MacGregor
S J
SJ
Given
M J
MJ
Deppe
C
C
Cook
N
N
D000256:Adenoviridae / Q000528:radiation effects*; D004203:Disinfection / Q000379:methods*; D017955:Poliovirus / Q000528:radiation effects*; D014466:Ultraviolet Rays