Natriuretic peptides in cardiovascular diseases.
The natriuretic peptide family comprises atrial natriuretic peptide (ANP), brain natriuretic peptide (BNP), C-type natriuretic peptide (CNP), dendroaspis natriuretic peptide (DNP), and urodilatin. The activities of natriuretic peptides and endothelins are strictly associated with each other. ANP and BNP inhibit endothelin-1 (ET-1) production. ET-1 stimulates natriuretic peptide synthesis. All natriuretic peptides are synthesized from polypeptide precursors. Changes in natriuretic peptides and endothelin release were observed in many cardiovascular diseases: e.g. chronic heart failure, left ventricular dysfunction and coronary artery disease.
Piechota
Mariusz
M
Department of Anaesthesiology and Intensive Care Unit, Boleslaw Szarecki University Hospital No. 5 in Łódź, Medical University in Łódź, Łódź, Poland.
Banach
Maciej
M
Jacoń
Anna
A
Rysz
Jacek
J
D000595:Amino Acid Sequence; D002318:Cardiovascular Diseases / Q000235:genetics / Q000378:metabolism*; D016232:Endothelins / Q000378:metabolism; D006801:Humans; D008969:Molecular Sequence Data; D045265:Natriuretic Peptides / Q000737:chemistry / Q000378:metabolism*
D016232:Endothelins; D045265:Natriuretic Peptides