title: Modeling of the bioactivated nanopore devices.
abstract: This paper presents the modeling of the electrical properties of bioactivated nanopores, customized nanopore devices with a biological macromolecule attached in the pore as the probe. These devices are capable of detecting and analyzing interactions between the attached biomolecule and the molecules in the analyte at a single molecule level.
authors.affiliation: Dept. of Electr. Eng., Stanford Univ., CA 94305, USA. atalasaz@stanford.edu
authors.forename: AmirAli H
authors.initials: AH
authors.lastname: Talasaz
authors.forename: Yang
authors.initials: Y
authors.lastname: Liu
authors.forename: Mostafa
authors.initials: M
authors.lastname: Ronaghi
authors.forename: Ronald W
authors.initials: RW
authors.lastname: Davis
mesh_terms: D001681:Biological Assay / Q000295:instrumentation / Q000379:methods; D001704:Biopolymers / Q000032:analysis / Q000737:chemistry*; D015374:Biosensing Techniques / Q000295:instrumentation* / Q000379:methods; D003198:Computer Simulation; D017076:Computer-Aided Design; D004563:Electrochemistry / Q000295:instrumentation / Q000379:methods; D004867:Equipment Design; D019544:Equipment Failure Analysis; D008567:Membranes, Artificial; D008839:Microelectrodes; D008956:Models, Chemical; D015336:Molecular Probe Techniques / Q000295:instrumentation*; D049329:Nanostructures / Q000737:chemistry* / Q000648:ultrastructure*; D016062:Porosity
chemical_list: D001704:Biopolymers; D008567:Membranes, Artificial