Clinical impact of a PCR assay for rapid identification of Klebsiella pneumoniae in blood cultures.
The clinical impact of a rapid PCR identification assay for Klebsiella pneumoniae in positive blood cultures was prospectively evaluated. Multivariate analysis identified the rapid PCR assay as the only significant factor in decreasing the time lapse preceding the initiation of appropriate antimicrobial therapy (hazards ratio, 3.03; confidence interval, 1.62 to 5.68; P, 0.001).
Neuberger
A
A
Department of Internal Medicine, Rambam Health Care Campus, Haifa, Israel.
Oren
I
I
Sprecher
H
H
D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001769:Blood / Q000382:microbiology*; D006801:Humans; D007710:Klebsiella Infections / Q000175:diagnosis* / Q000188:drug therapy*; D007711:Klebsiella pneumoniae / Q000235:genetics / Q000302:isolation & purification*; D016133:Polymerase Chain Reaction / Q000379:methods*; D011446:Prospective Studies; D013997:Time Factors
D000900:Anti-Bacterial Agents