title: Peritoneal small solute transport rate is related to the malnutrition inflammation score in peritoneal dialysis patients.
abstract: OBJECTIVE
  A high peritoneal membrane transport status and peritoneal albumin leakage are determinants of morbidity and mortality in patients receiving continuous ambulatory peritoneal dialysis. In this study, we analyzed the relationship between the malnutrition inflammation score, peritoneal transport status, and 24-hour peritoneal albumin leakage in patients receiving peritoneal dialysis.
  
  
  METHODS
  Sixty-six patients receiving peritoneal dialysis (male-female ratio 30/36; age 46.2 +/- 14.1 years; mean duration of peritoneal dialysis 32.4 +/- 23.9 months) who had experienced no attacks of peritonitis within the prior 6 months were included.
  
  
  RESULTS
  The malnutrition inflammation score was positively correlated with the serum C-reactive protein concentration, dialysate/plasma creatinine ratio, and 24-hour peritoneal albumin leakage. Triceps and biceps skinfold thicknesses and serum concentrations of prealbumin, total cholesterol, and triglyceride were negatively correlated with the malnutrition inflammation score. Multiple linear regression analysis showed that the malnutrition inflammation score was independently associated with the dialysate/plasma creatinine ratio (p = 0.039) and 24-hour peritoneal albumin amount (p = 0.005).
  
  
  CONCLUSIONS
  High peritoneal transport status and peritoneal albumin leakage are significantly associated with the malnutrition inflammation score.
authors.affiliation: Department of Nephrology, Baskent University Faculty of Medicine, Ankara, Turkey.
authors.forename: Siren
authors.initials: S
authors.lastname: Sezer
authors.forename: Rengin
authors.initials: R
authors.lastname: Elsurer
authors.forename: Baris
authors.initials: B
authors.lastname: Afsar
authors.forename: Zubeyde
authors.initials: Z
authors.lastname: Arat
authors.forename: Nurhan F
authors.initials: NF
authors.lastname: Ozdemir
authors.forename: Mehmet
authors.initials: M
authors.lastname: Haberal
mesh_terms: D000328:Adult; D000418:Albumins / Q000032:analysis / Q000378:metabolism*; D001202:Ascitic Fluid / Q000378:metabolism*; D001692:Biological Transport; D015331:Cohort Studies; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000175:diagnosis / Q000401:mortality / Q000628:therapy*; D007677:Kidney Function Tests; D016014:Linear Models; D008297:Male; D044342:Malnutrition / Q000175:diagnosis* / Q000401:mortality; D008875:Middle Aged; D015999:Multivariate Analysis; D010531:Peritoneal Dialysis, Continuous Ambulatory / Q000009:adverse effects / Q000379:methods*; D010538:Peritonitis / Q000175:diagnosis* / Q000401:mortality; D010539:Permeability; D011336:Probability; D011379:Prognosis; D018570:Risk Assessment; D016019:Survival Analysis
chemical_list: D000418:Albumins