Diet and survival after prostate cancer diagnosis.
Prostate cancer is the most commonly diagnosed non-skin cancer in men in the United States. Among environmental factors, diet may play a particularly important role in its incidence, progression, and clinical outcome. This article reviews the findings of eight observational studies and 17 intervention or laboratory trials on the effect of plant-based diets and plant nutrients on both the progression and clinical outcome of prostate cancer as well as additional studies examining mechanisms that may explain dietary effects. While additional long-term therapeutic clinical trials are needed to further elucidate the role of diet, these early investigations suggest that a recommendation for individual patients to shift their diets toward plant foods may serve as an important component of the tertiary treatment of prostate cancer.
Berkow
Susan E
SE
George Mason University, Department of Global and Community Health, 1211 Tatum Drive, Alexandria, VA 22307, USA. susan@susanberkow.com
Barnard
Neal D
ND
Saxe
Gordon A
GA
Ankerberg-Nobis
Trulie
T
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D014676:Diet, Vegetarian; D006801:Humans; D008297:Male; D008875:Middle Aged; D010945:Plants, Edible; D011471:Prostatic Neoplasms / Q000178:diet therapy* / Q000401:mortality; D016032:Randomized Controlled Trials as Topic; D016019:Survival Analysis; D014481:United States