Neuropsychological deficits in childhood epilepsy syndromes.
Seizure disorders are relatively common in childhood, and the International League Against Epilepsy (ILAE) provides a hierarchical classification system to define seizure types. At the final level of classification, specific epilepsy syndromes are defined that represent a complex of signs and symptoms unique to an epilepsy condition. The present review discusses the issues related to several of these epilepsy syndromes in childhood, including those classified as generalized idiopathic epilepsies (e.g., childhood absence epilepsy, juvenile absence epilepsy, juvenile myoclonic epilepsy), focal epilepsies (benign rolandic epilepsy, occipital epilepsy, temporal lobe epilepsy, frontal lobe epilepsy) and the "epileptic encephalopathies," including Dravet's Syndrome, West Syndrome, Lennox-Gastaut Syndrome, Myoclonic Astatic Epilepsy, and Landau-Kleffner Syndrome. For each syndrome, the epidemiology, clinical manifestations, treatments, and neuropsychological findings are discussed.
MacAllister
William S
WS
New York University Comprehensive Epilepsy Center, 403 East 34th Street, 4th floor, New York, NY, 10016, USA. William.macallister@med.nyu.edu
Schaffer
Sarah G
SG
D000293:Adolescent; D001927:Brain Diseases / Q000150:complications / Q000523:psychology; D002648:Child; D002675:Child, Preschool; D003071:Cognition; D003072:Cognition Disorders / Q000150:complications* / Q000523:psychology; D004827:Epilepsy / Q000145:classification / Q000150:complications / Q000523:psychology*; D006801:Humans; D009483:Neuropsychological Tests; D000297:Psychology, Adolescent; D002666:Psychology, Child; D012640:Seizures / Q000145:classification* / Q000209:etiology / Q000523:psychology; D013577:Syndrome