title: Abdominal aortic aneurysm repair in octogenarians: myth or reality?
abstract: OBJECTIVE
  We studied the thirty-day mortality and morbidity rate to assess the value of conventional open repair vs endovascular aortic repair (EVAR) in an elderly population presenting with a ruptured, symptomatic or asymptomatic abdominal aortic aneurysm (AAA) undergoing emergency, urgent or elective repair.
  
  
  METHODS
  During the period from January 2004 to May 2007, 329 consecutive patients were treated for AAA in our Department. Among these, 81 (24.6%) were aged >80 years (mean age 83.6, range 80-95 years). These older patients were divided into groups according to their clinical presentation: ruptured AAA group (rAAA) - 22 cases (4 emergency EVAR, 18 emergency open repair); symptomatic non-ruptured AAA group (sAAA) - 15 cases (11 urgent EVAR, 4 urgent open repair); asymptomatic AAA group (asAAA) - 44 cases (32 elective EVAR, 12 elective open repair). The main outcome measures were 30-day mortality and 30-day morbidity rate.
  
  
  RESULTS
  The mortality rate following open surgery vs EVAR was 66.6% vs 50% (P=NS) in the rAAA group, 25% vs 0% (P=NS) in the sAAA group, and 9% vs 3.2% (P=NS) in the asAAA group. When comparing postoperative morbidities in the octogenarians, 3 of the patients that received EVAR (6.4%) and 15 of those that received open repair (48.4%) had a severe complication (P<0.01).
  
  
  CONCLUSIONS
  The introduction of EVAR has considerably changed the balance of risks and benefits for AAA treatment. Our study confirms the high mortality rate for octogenarians with rAAA and haemodynamic instability, and supports the value of an active EVAR approach for octogenarians with AAA to prevent rupture. Moreover, the introduction of endovascular techniques as part of an overall treatment algorithm for ruptured AAAs appears to be potentially associated with improved outcomes in terms of mortality and morbidity as compared to open surgical repairs alone.
authors.affiliation: Vascular and Endovascular Surgery Unit, Department of Surgery, University of Siena, Siena, Italy.
authors.forename: G
authors.initials: G
authors.lastname: de Donato
authors.forename: C
authors.initials: C
authors.lastname: Setacci
authors.forename: E
authors.initials: E
authors.lastname: Chisci
authors.forename: F
authors.initials: F
authors.lastname: Setacci
authors.forename: M
authors.initials: M
authors.lastname: Giubbolini
authors.forename: P
authors.initials: P
authors.lastname: Sirignano
authors.forename: G
authors.initials: G
authors.lastname: Galzerano
authors.forename: A
authors.initials: A
authors.lastname: Cappelli
authors.forename: M
authors.initials: M
authors.lastname: Pieraccini
authors.forename: G
authors.initials: G
authors.lastname: Palasciano
mesh_terms: D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D017544:Aortic Aneurysm, Abdominal / Q000401:mortality / Q000601:surgery*; D001019:Aortic Rupture / Q000401:mortality / Q000601:surgery*; D001807:Blood Vessel Prosthesis; D019917:Blood Vessel Prosthesis Implantation / Q000379:methods*; D016009:Chi-Square Distribution; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000401:mortality; D016896:Treatment Outcome