title: Cardiovascular disease on a global scale: defining the path forward for research and practice.
abstract: During the 2006 World Congress of Cardiology meeting in Barcelona, the Virtual Coordinating Centre for Global Collaborative Cardiovascular Research (VIGOUR) group held a symposium examining potential approaches to understanding and controlling the explosive worldwide growth of cardiovascular disease and its attendant morbidity and mortality. Over the last 20 years, the global nature of many problems in health care has become much more evident. In the realm of health, this has meant that countries across the globe have started to experience the same kinds of behavioural shifts (overeating, reduced physical activity and smoking), and with them massive increases in cardiovascular risk factors, observed over the last century particularly in North America and Western Europe. This VIGOUR symposium focused on what actions can be taken now to prepare for this future in which prevention and treatment of cardiovascular disease will be a major public health issue in a much larger proportion of the world's countries. The participants focused on four major areas where they saw important opportunities: (i) the development of high quality, contemporaneous data sources that can be used to study and improve the processes, treatments and outcomes of cardiovascular diseases globally; (ii) the feasibility and resource/health economic implications of any proposed potential solutions need to be carefully defined; (iii) models/systems must be identified that can be used to guide effective interventions targeting health problems of large populations at an affordable price; (iv) academic research organizations need to assume a more active role in the health-care system both through their traditional activities in discovery research and developing evidence-based medicine along with translation of research findings into effective interventions that improve the public health.
authors.affiliation: Division of Cardiology, Department of Medicine, Duke Clinical Research Institute, Duke University Medical Center, PO Box 17969, Durham, NC 27715, USA. daniel.mark@duke.edu
authors.forename: Daniel B
authors.initials: DB
authors.lastname: Mark
authors.forename: Frans J
authors.initials: FJ
authors.lastname: Van de Werf
authors.forename: R John
authors.initials: RJ
authors.lastname: Simes
authors.forename: Harvey D
authors.initials: HD
authors.lastname: White
authors.forename: Lars C
authors.initials: LC
authors.lastname: Wallentin
authors.forename: Robert M
authors.initials: RM
authors.lastname: Califf
authors.forename: Paul W
authors.initials: PW
authors.lastname: Armstrong
mesh_terms: D002318:Cardiovascular Diseases / Q000191:economics / Q000401:mortality / Q000517:prevention & control*; D002986:Clinical Trials as Topic; D019317:Evidence-Based Medicine / Q000191:economics / Q000379:methods; D005240:Feasibility Studies; D014943:Global Health; D006302:Health Services Research / Q000191:economics / Q000379:methods*; D006801:Humans; D007391:International Cooperation; D011314:Preventive Health Services / Q000191:economics / Q000379:methods*; D012042:Registries; D009626:Terminology as Topic