[Tpeak-Tend interval and risk of cardiac events in patients with Brugada syndrome].
OBJECTIVE
To evaluate the possible association between Tpeak-Tend (Tp-e) interval in surface standard ECG and cardiac events in patients with Brugada syndrome (BrS).


METHODS
Tp-e interval in surface standard ECG was compared between BrS patients (n = 23, all males) and paroxysmal supraventricular tachycardia (PSVT) patients (n = 20, all males) as well as between BrS patients with (n = 16) or without (n = 7) cardiac events.


RESULTS
There was significant difference in Tp-e interval between BrS patients and PSVT patients [(109.57 +/- 22.86) ms vs. (88.50 +/- 13.08) ms, P < 0.05]. Tp-e interval was also significantly longer in BrS patients with cardiac events (syncope, clinical ventricular fibrillation and induced VF during electrophysiological study) than BrS patients without cardiac events [(118.12 +/- 20.40) ms vs. (90.00 +/- 15.27) ms, P < 0.05] while Tp-e interval was similar between BrS patients without cardiac events and PSVT patients (P > 0.05).


CONCLUSIONS
The prolongation of Tp-e (> or = 120 ms) was associated with higher cardiac events in BrS patients.
Wang
Jin-feng
JF
Department of Cardiology, First Affiliated Hospital, Nanjing Medical University, Nanjing 210029, China.
Shan
Qi-jun
QJ
Yang
Bing
B
Chen
Ming-long
ML
Zou
Jian-gang
JG
Chen
Chun
C
Xu
Dong-jie
DJ
Cao
Ke-jiang
KJ
D000328:Adult; D053840:Brugada Syndrome / Q000175:diagnosis* / Q000503:physiopathology*; D004562:Electrocardiography; D006801:Humans; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D014693:Ventricular Fibrillation / Q000175:diagnosis / Q000503:physiopathology*