title: A case of spatial neglect dysgraphia in Wilson's Disease.
abstract: We report here on a single neuropsychological case study of a young girl, KH, who presented with Wilson's Disease (WD) associated with a peripheral spatial neglect dysgraphia without major problems in the standard clinical tests of spatial neglect. Few studies have demonstrated a visuospatial deficit in WD and to date there has been no report of neglect syndrome arising from WD. However, recent studies have demonstrated that neglect is frequently associated with brain damage including the primary site of WD, the basal ganglia. KHs writing abilities were evaluated just after her admission to the rehabilitation department and 6 months later. The baseline evaluation demonstrated that KH had neglect dysgraphia with verbal stimuli (e.g., words or sentences) although her deficit was less evident in drawing multiple geometric shapes. Six months after the initial evaluation, KH showed evidence of neglect dysgraphia only when writing was associated with a secondary memory task. KHs writing performance is discussed with reference to previous cases of spatial neglect dysgraphia and in the context of spatial neglect. We suggest that the asymmetry between verbal writing and nonverbal drawing disturbances was caused by different attentional loads.
authors.affiliation: Université Paris Descartes (Paris 5) and Laboratoire de Psychologie et de Neurosciences Cognitives (CNRS-FRE2987), Boulogne-Billancourt Cedex, France. laurent.auclair@univ-paris5.fr
authors.forename: Laurent
authors.initials: L
authors.lastname: Auclair
authors.forename: Eric
authors.initials: E
authors.lastname: Siéroff
authors.forename: Serdar
authors.initials: S
authors.lastname: Kocer
mesh_terms: D000293:Adolescent; D000381:Agraphia / Q000209:etiology*; D005260:Female; D006527:Hepatolenticular Degeneration / Q000150:complications*; D006801:Humans; D007802:Language; D009483:Neuropsychological Tests; D010468:Perceptual Disorders / Q000209:etiology*; D011597:Psychomotor Performance; D013028:Space Perception; D014956:Writing