title: Introduction to clinical and laboratory (small-animal) image registration and fusion.
abstract: Imaging has long been a vital component of clinical medicine and, increasingly, of biomedical research in small-animals. Clinical and laboratory imaging modalities can be divided into two general categories, structural (or anatomical) and functional (or physiological). The latter, in particular, has spawned what has come to be known as "molecular imaging". Image registration and fusion have rapidly emerged as invaluable components of both clinical and small-animal imaging and has lead to the development and marketing of a variety of multi-modality, e.g. PET-CT, devices which provide registered and fused three-dimensional image sets. This paper briefly reviews the basics of image registration and fusion and available clinical and small-animal multi-modality instrumentation.
authors.affiliation: Department of Medical Physics, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA. ZanzoniP@MSKCC.org
authors.forename: Pat B
authors.initials: PB
authors.lastname: Zanzonico
authors.forename: Sadek A
authors.initials: SA
authors.lastname: Nehmeh
mesh_terms: D000465:Algorithms; D000818:Animals; D003952:Diagnostic Imaging / Q000295:instrumentation* / Q000379:methods / Q000662:veterinary*; D004867:Equipment Design; D007089:Image Enhancement / Q000295:instrumentation*; D007090:Image Interpretation, Computer-Assisted / Q000295:instrumentation* / Q000379:methods; D021621:Imaging, Three-Dimensional / Q000379:methods / Q000662:veterinary; D010363:Pattern Recognition, Automated / Q000379:methods*; D013382:Subtraction Technique / Q000295:instrumentation* / Q000662:veterinary*