title: [Diagnostic value of multidetector spiral computed tomography in identifying the composition of coronary atherosclerotic plaques].
abstract: OBJECTIVE
  To estimate the feasibility of 16-multidetector spiral computed tomography (16-MDCT) on detecting coronary plaques in comparison with intravascular ultrasound (IVUS).
  
  
  METHODS
  Sixty-eight patients suspected of coronary heart diseases were examined by 16-MDCT, quantitative coronary angiography (QCA) and IVUS. Coronary stenosis was defined as lumen diameter reduction (DS) >or= 50%. Hounsfield units (HU) were used to determine different types of plaques: soft plaque (<or= 50 HU), fibrous plaque (50 - 119 HU) and calcified plaque (>or= 120 HU).
  
  
  RESULTS
  Compared to QCA, the sensitivity and the specificity for patients with DS >or= 50% were 91.8% (112/122) and 97.8% (556/568) respectively, the positive and negative predictive value were 90.3% (112/124) and 98.2% (556/566) respectively. In 96 plaques evaluated both by 16-MDCT and IVUS, 20 and 21 soft plaques, 37 and 36 fibrous plaques, 39 and 38 calcified plaques were identified by 16-MDCT and IVUS respectively. HU value of soft (11 +/- 36), fibrous (83 +/- 20), and calcified (292 +/- 80) plaques were significantly different (P < 0.05).
  
  
  CONCLUSIONS
  Noninvasive 16-MDCT could correctly estimate coronary stenosis and coronary plaques compositions.
authors.affiliation: Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai 200032, China.
authors.forename: Ming-hui
authors.initials: MH
authors.lastname: Wang
authors.forename: Jun-bo
authors.initials: JB
authors.lastname: Ge
authors.forename: Ke-qiang
authors.initials: KQ
authors.lastname: Wang
authors.forename: Zhi-qing
authors.initials: ZQ
authors.lastname: Ling
authors.forename: Ju-ying
authors.initials: JY
authors.lastname: Qian
authors.forename: Lei
authors.initials: L
authors.lastname: Ge
authors.forename: Feng
authors.initials: F
authors.lastname: Zhang
mesh_terms: D000368:Aged; D050197:Atherosclerosis / Q000000981:diagnostic imaging*; D017023:Coronary Angiography; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D036542:Tomography, Spiral Computed / Q000379:methods*; D018084:Ultrasonography, Interventional