Synthesis of alpha-oximinoketones under ultrasound irradiation.
The reaction of 6-acylmethylphenanthridines with isoamyl nitrite results alpha-oximino-6-acylmethylphenanthridines in 73-95% yields in DMF under ultrasound irradiation. Compared with conventional methods, the main advantages of the present procedure are milder conditions, shorter reaction time and higher yields.
Mehrabi
Hossein
H
Department of Chemistry, Rafsanjan Vali-e Asr University, Rafsanjan 77176, Iran. Electronic address: mehraby_h@yahoo.com.
D000680:Amyl Nitrite / Q000031:analogs & derivatives / Q000737:chemistry / Q000528:radiation effects; D007202:Indicators and Reagents; D009682:Magnetic Resonance Spectroscopy; D015538:Nitrosation / Q000528:radiation effects; D010091:Oximes / Q000138:chemical synthesis*; D010617:Phenanthridines / Q000138:chemical synthesis* / Q000737:chemistry / Q000528:radiation effects; D013055:Spectrophotometry, Infrared; D013431:Sulfates / Q000737:chemistry; D014465:Ultrasonics
D007202:Indicators and Reagents; D010091:Oximes; D010617:Phenanthridines; D013431:Sulfates; C012036:sodium sulfate; C048958:isoamyl nitrite; D000680:Amyl Nitrite