title: [Baclofen dose in a screening test and in a baclofen pump filling--is there any differences].
abstract: Spasticity is one from many clinical signs appearing in head and spinal cord injury and it is characterized by increased muscle tone with increased tendom reflex and reccurent spasms. Intrathecal baclofen therapy is surgical method for treatment of severe spasticity and a pump implantation is preceded by baclofen screening test. In this study we compared a bolus intrathecal injection given in a screening test with doses uses for filling a baclofen pump. In selected group we observed increased Baclofen dose due to dose given in screening test.
authors.affiliation: Oddział Neurochirurgii, Pracownia Neurorehabilitacji, Uniwersytecki Szpital Dzieciecy w Krakowie. przygrzy@poczta.onet.pl
authors.forename: Przemysław
authors.initials: P
authors.lastname: Grzegorzewski
authors.forename: Zdzisław
authors.initials: Z
authors.lastname: Kawecki
authors.forename: Anna
authors.initials: A
authors.lastname: Swierczyńska
authors.forename: Alicja
authors.initials: A
authors.lastname: Fafara
authors.forename: Stanisław
authors.initials: S
authors.lastname: Kwiatkowski
mesh_terms: D000293:Adolescent; D001418:Baclofen / Q000008:administration & dosage*; D002648:Child; D002985:Clinical Protocols; D004305:Dose-Response Relationship, Drug; D004361:Drug Tolerance; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015918:Infusion Pumps, Implantable; D007278:Injections, Spinal; D008297:Male; D009125:Muscle Relaxants, Central / Q000008:administration & dosage*; D009128:Muscle Spasticity / Q000188:drug therapy* / Q000209:etiology
chemical_list: D009125:Muscle Relaxants, Central; D001418:Baclofen