title: Fatal coinfection with Legionella pneumophila serogroup 8 and Aspergillus fumigatus.
abstract: Legionella pneumophila is an important cause of community-acquired and nosocomial pneumonia. We report on a patient who simultaneously developed L. pneumophila serogroup 8 pneumonia and Aspergillus fumigatus lung abscesses. Despite appropriate treatments, Aspergillus disease progressed with metastasis. Coinfections caused by L. pneumophila and A. fumigatus remain exceptional. In apparently immunocompetent patients, corticosteroid therapy is a key risk factor for aspergillosis.
authors.affiliation: Laboratoire de Bactériologie-Hygiène, CHU de Nantes, 44093 Nantes Cedex, France.
authors.forename: Aurélie
authors.initials: A
authors.lastname: Guillouzouic
authors.forename: Pascale
authors.initials: P
authors.lastname: Bemer
authors.forename: Françoise
authors.initials: F
authors.lastname: Gay-Andrieu
authors.forename: Cédric
authors.initials: C
authors.lastname: Bretonnière
authors.forename: Didier
authors.initials: D
authors.lastname: Lepelletier
authors.forename: Pierre-Joachim
authors.initials: PJ
authors.lastname: Mahé
authors.forename: Daniel
authors.initials: D
authors.lastname: Villers
authors.forename: Sophie
authors.initials: S
authors.lastname: Jarraud
authors.forename: Alain
authors.initials: A
authors.lastname: Reynaud
authors.forename: Stéphane
authors.initials: S
authors.lastname: Corvec
mesh_terms: D001228:Aspergillosis / Q000150:complications* / Q000188:drug therapy; D001232:Aspergillus fumigatus / Q000302:isolation & purification*; D017809:Fatal Outcome; D006801:Humans; D016952:Legionella pneumophila / Q000145:classification / Q000302:isolation & purification*; D007877:Legionnaires' Disease / Q000150:complications* / Q000188:drug therapy; D008169:Lung Abscess / Q000382:microbiology; D008297:Male; D008875:Middle Aged; D013902:Radiography, Thoracic; D014057:Tomography, X-Ray Computed