title: [Single-dose toxicological test for leptospirosis vaccine vax-SPIRAL in mice].
abstract: The single-dose toxicological test for the leptospirosis vaccine vax-SPIRAL was made in rats. No clinical toxicity symptoms were found. The differences between the evaluated variables were not important from the biological point of view.
authors.affiliation: Instituto Finlay, Ciudad de La Habana, Cuba.
authors.forename: Juan Francisco Infante
authors.initials: JF
authors.lastname: Bourzac
authors.forename: Sergio Sifontes
authors.initials: SS
authors.lastname: Rodríguez
authors.forename: Martha González
authors.initials: MG
authors.lastname: González
authors.forename: Viviana Pérez
authors.initials: VP
authors.lastname: Amat
authors.forename: Mildrey Fariñas
authors.initials: MF
authors.lastname: Medina
mesh_terms: D000818:Animals; D001428:Bacterial Vaccines / Q000008:administration & dosage / Q000633:toxicity*; D004195:Disease Models, Animal; D005260:Female; D007921:Leptospira interrogans / Q000276:immunology*; D007922:Leptospirosis / Q000517:prevention & control*; D008297:Male; D051379:Mice; D013997:Time Factors; D018675:Toxicity Tests
chemical_list: D001428:Bacterial Vaccines