title: Combining near infrared spectroscopy and functional MRI during continuous performance test in healthy subjects.
abstract: The study of cognitive functions is a major challenge of the modern functional imaging. Activation of specific cerebral area is obtained from the observation of physic characteristic affected by changes occurring in the blood flow resulting from an increased metabolic consumption. In this work two imaging techniques are used, the functional magnetic resonance (fMRI) and the near infrared spectroscopy (NIRS), in order to assess cerebral performance during the execution of a well known sustained attention task, the Conners' continuous performance test (CPT). With fMRI analysis were found activations in the frontal, parietal and supplementary motor areas, whereas NIRS system showed a region-wise difference in the variations of parameters and different activation trend localized in the middle-right frontal area. The combined analysis of the two techniques allows to obtain more detailed information and places itself as a first step toward a result of multimodal image integration.
authors.affiliation: Dept. of Biomed. Eng., Polytech. Univ. of Milan, Italy. michele.butti@polimi.it
authors.forename: Michele
authors.initials: M
authors.lastname: Butti
authors.forename: Aurora
authors.initials: A
authors.lastname: Pastori
authors.forename: Anna
authors.initials: A
authors.lastname: Merzagora
authors.forename: Anna
authors.initials: A
authors.lastname: Bianchi
authors.forename: Alessandra
authors.initials: A
authors.lastname: Bardoni
authors.forename: Vincenzo
authors.initials: V
authors.lastname: Branca
authors.forename: Antonella
authors.initials: A
authors.lastname: Costa
authors.forename: Sergio
authors.initials: S
authors.lastname: Cerutti
authors.forename: Gianluigi
authors.initials: G
authors.lastname: Reni
mesh_terms: D000328:Adult; D001288:Attention / Q000502:physiology*; D001921:Brain / Q000502:physiology*; D001931:Brain Mapping; D003071:Cognition / Q000502:physiology*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D010101:Oxygen Consumption / Q000502:physiology*; D012016:Reference Values; D019265:Spectroscopy, Near-Infrared / Q000379:methods*; D018511:Systems Integration; D013647:Task Performance and Analysis