title: Incidence and predictors of abnormal fasting plasma glucose among the university hospital employees in Thailand.
abstract: The purposes of this study were to determine the incidence rates and predictors of type 2 diabetes and impaired fasting plasma glucose (IFG) among the employees of a university hospital in Bangkok, Thailand. Totally 2370 and 1619 workers without diabetes and IFG at baseline, respectively, who were +35 years old were followed up during 2001-2005. Type 2 diabetes incidence rates (95% CI) were 13.6 (8.4-22.3) and 6.4 (4.5-9.1) per 1000 PYs, respectively, for men and women, while those of the IFG were 37.8 (26.3-54.4) and 23.6 (19.3-29.0) per 1000 PYs, respectively, for both genders. Baseline FBS predicted future IFG risk even at the levels as low as 63-70 mg/dl. The OR (95% CI) of IFG for those with baseline FPG of 63-70, 71-80, and >80 mg/dl-compared to those with baseline FPG < or =62 mg/dl-were 2.51 (1.12-5.64), 5.39 (2.51-11.56), and 8.30 (3.67-18.75), respectively. Future diabetes risk was observed only in those with baseline FPG of 96 mg/dl or higher, with the OR (95% CI) of 6.0 (2.29-15.75). In conclusion, baseline FPG even at the level as low as 63-70 mg/dl predicts future IFG risk among a hospital employee group in Thailand, while increased diabetes risk was found only in those at the FBS level of > or =96 mg/dl.
authors.affiliation: Department of Preventive and Social Medicine, Faculty of Medicine, Chulalongkorn University, Pathumwan, Bangkok 10330, Thailand. wjiamjar@hotmail.com
authors.forename: Wiroj
authors.initials: W
authors.lastname: Jiamjarasrangsi
authors.forename: Vitool
authors.initials: V
authors.lastname: Lohsoonthorn
authors.forename: Somrat
authors.initials: S
authors.lastname: Lertmaharit
authors.forename: Somkiat
authors.initials: S
authors.lastname: Sangwatanaroj
mesh_terms: D000328:Adult; D001786:Blood Glucose / Q000378:metabolism*; D001794:Blood Pressure; D002318:Cardiovascular Diseases / Q000453:epidemiology*; D003924:Diabetes Mellitus, Type 2 / Q000453:epidemiology*; D005215:Fasting; D005260:Female; D018149:Glucose Intolerance / Q000453:epidemiology*; D006785:Hospitals, University / Q000706:statistics & numerical data*; D006801:Humans; D006973:Hypertension / Q000453:epidemiology; D015994:Incidence; D008297:Male; D008875:Middle Aged; D010808:Physical Examination / Q000706:statistics & numerical data; D015995:Prevalence; D013785:Thailand
chemical_list: D001786:Blood Glucose