title: Development and validation of the system of quality of life instruments for cancer patients: lung cancer (QLICP-LU).
abstract: Using the structured group methods (nominal and focus group) and the theory in instrument development, the quality of life instrument for lung cancer (QLICP-LU) with Chinese cultural background was developed, and evaluated based on the data from a sample of 85 in-patients of lung cancer. Statistical methods used were correlation analysis, factor analysis and paired t-test, etc. The results showed that test-retest reliability of the overall scale was 0.78, and test-retest reliability and internal consistency alpha for most domains were higher than 0.70; correlation and factor analysis demonstrated good construct validity; criterion-related validity were confirmed given FACT-L and QLQ-LC43 (QLQ-C30 plus QLQ-LC13) as the criterions; statistically significant changes were found for each domain and the overall scale with standardized response mean SRM being greater than 0.80 except for the social function domain. We conclude that the QLICP-LU can be used to measure QOL for patients with lung cancer with better validity, reliability and responsiveness in China.
authors.affiliation: School of Public Health, Kunming Medical College, Kunming 650031, Yunnan, China; Department of Biostatistics and Computational Biology, University of Rochester, Rochester, NY 14642, USA. Electronic address: chonghua_wan@urmc.rochester.edu.
authors.forename: Chonghua
authors.initials: C
authors.lastname: Wan
authors.affiliation: Yunnan Tumor Hospital, Kunming 650031, China.
authors.forename: Yubo
authors.initials: Y
authors.lastname: Lu
authors.affiliation: Department of Biostatistics and Computational Biology, University of Rochester, Rochester, NY 14642, USA.
authors.forename: Wan
authors.initials: W
authors.lastname: Tang
authors.affiliation: Department of Biostatistics and Computational Biology, University of Rochester, Rochester, NY 14642, USA.
authors.forename: Xin
authors.initials: X
authors.lastname: Tu
authors.affiliation: Yunnan Tumor Hospital, Kunming 650031, China.
authors.forename: Canzhen
authors.initials: C
authors.lastname: Zhang
authors.affiliation: Yunnan Tumor Hospital, Kunming 650031, China.
authors.forename: Gaofeng
authors.initials: G
authors.lastname: Li
authors.affiliation: Yunnan Tumor Hospital, Kunming 650031, China.
authors.forename: Lida
authors.initials: L
authors.lastname: Shen
authors.affiliation: School of Public Health, Kunming Medical College, Kunming 650031, Yunnan, China.
authors.forename: Jiahong
authors.initials: J
authors.lastname: Luo
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000523:psychology*; D008297:Male; D008875:Middle Aged; D011594:Psychometrics; D011788:Quality of Life