title: Relationship between susceptibility to antimicrobials and virulence factors in paediatric Escherichia coli isolates.
abstract: The in vitro susceptibilities to several antibiotics of 136 Escherichia coli strains containing virulence factors isolated from children with urinary tract infection were analysed. Escherichia coli strains were analysed by multiplex polymerase chain reaction for genes encoding the following virulence factors: pyelonephritis-associated pili (pap); S fimbriae (sfa); afimbrial adhesin I (afaI); haemolysin (hly); cytotoxic necrotizing factor I (cnfI); and aerobactin (aer). It was observed that the virulence genes increased antibiotic resistance of resistant strains and increased the sensitivity of susceptible strains.
authors.affiliation: Ankara University, Faculty of Health Sciences, Ankara, Turkey. munear@mynet.com
authors.forename: Münevver
authors.initials: M
authors.lastname: Arisoy
authors.forename: Abbas Yousefi
authors.initials: AY
authors.lastname: Rad
authors.forename: Ali
authors.initials: A
authors.lastname: Akin
authors.forename: Nejat
authors.initials: N
authors.lastname: Akar
mesh_terms: D000293:Adolescent; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D002648:Child; D002675:Child, Preschool; D004269:DNA, Bacterial / Q000235:genetics; D024881:Drug Resistance, Bacterial; D004926:Escherichia coli / Q000187:drug effects* / Q000235:genetics / Q000254:growth & development* / Q000302:isolation & purification; D004927:Escherichia coli Infections / Q000382:microbiology*; D005798:Genes, Bacterial; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008826:Microbial Sensitivity Tests; D016133:Polymerase Chain Reaction; D014552:Urinary Tract Infections / Q000382:microbiology*; D037521:Virulence Factors / Q000096:biosynthesis* / Q000235:genetics
chemical_list: D000900:Anti-Bacterial Agents; D004269:DNA, Bacterial; D037521:Virulence Factors