title: Hetisine-type diterpenoid alkaloids from the Bhutanese medicinal plant Aconitum orochryseum.
abstract: Investigation of Aconitum orochryseum, a Bhutanese traditional medicine ("gSo-ba Rig-pa") plant locally known as "Bong-kar", resulted in the isolation of three new hetisine-type diterpenoid alkaloids, named orochrine (1), 2-O-acetylorochrine (2), and 2-O-acetyl-7alpha-hydroxyorochrine (3), together with the previously reported alkaloids atisinium chloride (4) and virescenine (5). The structures of the new alkaloids were elucidated by spectroscopic data analysis.
authors.affiliation: Department of Chemistry, University of Wollongong, Wollongong, NSW 2522, Australia.
authors.forename: Phurpa
authors.initials: P
authors.lastname: Wangchuk
authors.forename: John B
authors.initials: JB
authors.lastname: Bremner
authors.forename: Siritron
authors.initials: S
authors.lastname: Samosorn
mesh_terms: D031841:Aconitum / Q000737:chemistry*; D000470:Alkaloids / Q000737:chemistry* / Q000302:isolation & purification*; D001631:Bhutan; D004224:Diterpenes / Q000737:chemistry* / Q000302:isolation & purification*; D015394:Molecular Structure; D010946:Plants, Medicinal / Q000737:chemistry*
chemical_list: C525475:2-O-acetyl-7alpha-hydroxyorochrine; C525474:2-O-acetylorochrine; D000470:Alkaloids; D004224:Diterpenes; C525473:orochrine