Hydrogenation processes in the synthesis of perfumery ingredients.
Homogeneous catalytic hydrogenation has played an important role in the development of modern organic synthesis. Indeed, the discovery of highly regio- and stereoselective catalysts for C=C and C=O bonds reductions has allowed the efficient synthesis of optically active compounds. As the fragrance industry has turned to synthetic ingredients to fulfill the need for novel, cost-effective, and environment-friendly products, the use of catalytic processes are more and more in demand. In this Account, we thus highlight the application of catalytic hydrogenation in the synthesis of fragrance ingredients.
Saudan
Lionel A
LA
Synthesis, Corporate R&D Division, Firmenich SA, PO Box 239, CH-1211 Geneva 8, Switzerland. lionel.saudan@firmenich.com