An ellagitannin, n-butyl gallate, two aryltetralin lignans, and an unprecedented diterpene ester from Pelargonium reniforme.
The structural diversity of the metabolic pool of Pelargonium reniforme was extended by the characterization of the 1C4-glucose based ellagitannin pelargoniin E, gallic acid n-butyl ester, (-)-4,4',9'-trihydroxy-3',5'-dimethoxy-2,7'-cyclolignan 9-O-beta-glucopyranoside and reniformin, a diterpene ester comprised of a diterpene acid with an uncommon -(CH2)(2)- bridging element linked to 2-(4-hydroxyphenyl)ethansulfonic acid. These metabolites were associated with the known (alpha,beta)-3,4-di-O-galloyl-glucopyranoside, 4,6-dihydroxy-2beta-glucopyranosyloxyacetophenone, 1-O-galloylglycerol, 6'-O-galloylsalidroside and (+)-isolariciresinol-9'-O-beta-glucopyranoside. All structures were established on the basis of spectroscopic methods.
Latté
Klaus Peter
KP
Freie Universität Berlin, Institute of Pharmacy, Pharmaceutical Biology, Königin-Luise-Str. 2+4, D-14195 Berlin, Germany.
Kaloga
Maki
M
Schäfer
Andreas
A
Kolodziej
Herbert
H
D002247:Carbon Isotopes; D004224:Diterpenes / Q000737:chemistry* / Q000302:isolation & purification; D004952:Esters / Q000737:chemistry* / Q000302:isolation & purification; D005707:Gallic Acid / Q000031:analogs & derivatives* / Q000737:chemistry* / Q000302:isolation & purification; D047348:Hydrolyzable Tannins / Q000737:chemistry* / Q000302:isolation & purification; D009682:Magnetic Resonance Spectroscopy / Q000379:methods / Q000592:standards; D008968:Molecular Conformation; D031316:Pelargonium / Q000737:chemistry* / Q000378:metabolism; D012015:Reference Standards; D013237:Stereoisomerism
D002247:Carbon Isotopes; D004224:Diterpenes; D004952:Esters; D047348:Hydrolyzable Tannins; D005707:Gallic Acid