Multilocus sequence typing analysis of Shigella flexneri isolates collected in Asian countries.
The multilocus sequence typing scheme used previously for phylogenetic analysis of Escherichia coli was applied to 107 clinical isolates of Shigella flexneri. DNA sequencing of 3423 bp throughout seven housekeeping genes identified eight new allele types and ten new sequence types among the isolates. S. flexneri serotypes 1-5, X and Y were clustered together in a group containing many allelic variants while serotype 6 formed a distinct group, as previously established.
Choi
Seon Young
SY
School of Biological Sciences, Seoul National University, Seoul 151-742, Republic of Korea.|International Vaccine Institute, San 4-8 Bongcheon 7 dong, Kwanak gu, Seoul 151-818, Republic of Korea.
Jeon
Yoon-Seong
YS
Interdisciplinary Program of Bioinformatics, Seoul National University, Seoul 151-742, Republic of Korea.|International Vaccine Institute, San 4-8 Bongcheon 7 dong, Kwanak gu, Seoul 151-818, Republic of Korea.
Lee
Je Hee
JH
School of Biological Sciences, Seoul National University, Seoul 151-742, Republic of Korea.|International Vaccine Institute, San 4-8 Bongcheon 7 dong, Kwanak gu, Seoul 151-818, Republic of Korea.
Choi
Boram
B
International Vaccine Institute, San 4-8 Bongcheon 7 dong, Kwanak gu, Seoul 151-818, Republic of Korea.
Moon
Sun Hwa
SH
International Vaccine Institute, San 4-8 Bongcheon 7 dong, Kwanak gu, Seoul 151-818, Republic of Korea.
von Seidlein
Lorenz
L
International Vaccine Institute, San 4-8 Bongcheon 7 dong, Kwanak gu, Seoul 151-818, Republic of Korea.
Clemens
John D
JD
International Vaccine Institute, San 4-8 Bongcheon 7 dong, Kwanak gu, Seoul 151-818, Republic of Korea.
Dougan
Gordon
G
The Wellcome Trust Sanger Institute, Hinxton, Cambridgeshire CB10 1SA, UK.
Wain
John
J
The Wellcome Trust Sanger Institute, Hinxton, Cambridgeshire CB10 1SA, UK.
Yu
Jun
J
The Wellcome Trust Sanger Institute, Hinxton, Cambridgeshire CB10 1SA, UK.
Lee
Je Chul
JC
School of Medicine, Kyungpook National University, Daegu 700-422, Republic of Korea.
Seol
Sung Yong
SY
School of Medicine, Kyungpook National University, Daegu 700-422, Republic of Korea.
Lee
Bok Kwon
BK
Laboratory of Enteric Infections, Department of Microbiology, National Institute of Health Korea, Republic of Korea.
Song
Jae-Hoon
JH
Division of Infectious Disease, Samsung Medical Center, Seoul, Republic of Korea.
Song
Manki
M
International Vaccine Institute, San 4-8 Bongcheon 7 dong, Kwanak gu, Seoul 151-818, Republic of Korea.
Czerkinsky
Cecil
C
International Vaccine Institute, San 4-8 Bongcheon 7 dong, Kwanak gu, Seoul 151-818, Republic of Korea.
Chun
Jongsik
J
Interdisciplinary Program of Bioinformatics, Seoul National University, Seoul 151-742, Republic of Korea.|School of Biological Sciences, Seoul National University, Seoul 151-742, Republic of Korea.|International Vaccine Institute, San 4-8 Bongcheon 7 dong, Kwanak gu, Seoul 151-818, Republic of Korea.
Kim
Dong Wook
DW
International Vaccine Institute, San 4-8 Bongcheon 7 dong, Kwanak gu, Seoul 151-818, Republic of Korea.
D000483:Alleles; D001208:Asia; D015373:Bacterial Typing Techniques; D016000:Cluster Analysis; D004269:DNA, Bacterial / Q000737:chemistry / Q000235:genetics; D004405:Dysentery, Bacillary / Q000382:microbiology*; D005838:Genotype; D006801:Humans; D008969:Molecular Sequence Data; D017422:Sequence Analysis, DNA; D012763:Shigella flexneri / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification*
D004269:DNA, Bacterial