title: Biophotonics applied to proteomics.
abstract: Since the completion of the human genome sequencing, our understanding of gene and protein function and their involvement in physiopathological states has increased dramatically, partly due to technological developments in photonics. Photonics is a very active area where new developments occur on a weekly basis, while established tools are adapted to fulfill the needs of other disciplines like genomics and proteomics. Biophotonics emerged at the interface of photonics and biology as a very straightforward and efficient approach to observe and manipulate living systems. In this chapter, we review the current applications of photonics and imaging to proteomics from 2D gels analysis to molecular imaging.
authors.affiliation: Novartis Institutes for BioMedical Research, Genome and Protein Sciences Systems Biology, Basel, Switzeland. michel_daniel.faupel@novartis.com
authors.forename: Michel
authors.initials: M
authors.lastname: Faupel
authors.forename: Débora
authors.initials: D
authors.lastname: Bonenfant
authors.forename: Patrick
authors.initials: P
authors.lastname: Schindler
authors.forename: Eric
authors.initials: E
authors.lastname: Bertrand
authors.forename: Dieter
authors.initials: D
authors.lastname: Mueller
authors.forename: Markus
authors.initials: M
authors.lastname: Stoeckli
authors.forename: Francis
authors.initials: F
authors.lastname: Bitsch
authors.forename: Tatiana
authors.initials: T
authors.lastname: Rohner
authors.forename: Dieter
authors.initials: D
authors.lastname: Staab
authors.forename: Jan
authors.initials: J
authors.lastname: Van Oostrum
mesh_terms: D015180:Electrophoresis, Gel, Two-Dimensional; D013058:Mass Spectrometry; D017785:Photons; D040901:Proteomics