[Fever, pneumonia and eosinophilia].
We present the case of a 71-year old man with acute eosinophilic pneumonia. By ruling out other common etiologies and by a positive lymphocyte transformation test the non-steroidal anti-inflammatory drug mefenamic acid was identified as the possible causative agent or this potentially life threatening lung disease. The clinical presentation, diagnosis, and treatment of acute eosinophilic pneumonia as a pulmonary manifestation of a drug-induced allergic reaction are discussed.
Berger
D
D
Medizinische Klinik, Bürgerspital Solothurn.
Pichler
W
W
Savic
S
S
Schoenenberger
R
R
Borer
H
H
D000368:Aged; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects* / Q000627:therapeutic use; D001992:Bronchoalveolar Lavage Fluid / Q000276:immunology; D003937:Diagnosis, Differential; D004342:Drug Hypersensitivity / Q000175:diagnosis* / Q000473:pathology; D004802:Eosinophilia / Q000209:etiology*; D004804:Eosinophils / Q000473:pathology; D005335:Fever of Unknown Origin / Q000209:etiology*; D006801:Humans; D008297:Male; D008528:Mefenamic Acid / Q000009:adverse effects* / Q000627:therapeutic use; D015207:Osteoarthritis, Hip / Q000188:drug therapy*; D011657:Pulmonary Eosinophilia / Q000139:chemically induced* / Q000175:diagnosis / Q000473:pathology
D000894:Anti-Inflammatory Agents, Non-Steroidal; D008528:Mefenamic Acid