Combining clindamycin 1%-benzoyl peroxide 5% gel with multiple therapeutic options.
This article reports on recent studies and case reports that evaluated the stability, tolerability, and efficacy of clindamycin 1%-benzoyl peroxide 5% tube gel in combination with topical retinoids and oral antibiotics. Overall, these combinations appeared to be well-tolerated, effective, and, as reported in the case studies, adaptable to common clinical practice.
Bikowski
Joseph
J
Department of Dermatology, Ohio State University, Columbus, USA.
Callender
Valerie D
VD
Del Rosso
James Q
JQ
Draelos
Zoe D
ZD
Tanghetti
Emil
E
D000152:Acne Vulgaris / Q000188:drug therapy*; D000068816:Adapalene; D000279:Administration, Cutaneous; D000284:Administration, Oral; D000293:Adolescent; D000328:Adult; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D001585:Benzoyl Peroxide / Q000008:administration & dosage / Q000627:therapeutic use*; D002981:Clindamycin / Q000008:administration & dosage / Q000627:therapeutic use*; D003879:Dermatologic Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D004338:Drug Combinations; D005260:Female; D005782:Gels; D006801:Humans; D007641:Keratolytic Agents / Q000008:administration & dosage / Q000627:therapeutic use; D008297:Male; D008911:Minocycline / Q000008:administration & dosage / Q000627:therapeutic use; D009281:Naphthalenes / Q000008:administration & dosage / Q000627:therapeutic use; D009539:Nicotinic Acids / Q000008:administration & dosage / Q000627:therapeutic use; D012176:Retinoids / Q000008:administration & dosage / Q000627:therapeutic use; D016896:Treatment Outcome; D014212:Tretinoin / Q000008:administration & dosage / Q000627:therapeutic use
D000900:Anti-Bacterial Agents; D003879:Dermatologic Agents; D004338:Drug Combinations; D005782:Gels; D007641:Keratolytic Agents; D009281:Naphthalenes; D009539:Nicotinic Acids; D012176:Retinoids; D000068816:Adapalene; D002981:Clindamycin; D014212:Tretinoin; C086827:tazarotene; D008911:Minocycline; D001585:Benzoyl Peroxide