Combining optical imaging and computational modeling to analyze structure and function of living neurons.
We are investigating the computational properties of principal neurons in the mammalian brain. To manage the small size and intricate structure of neuronal dendrites, we employ advanced optical imaging techniques in combination with automatic image reconstruction and computational modeling to study their complex spatio-temporal pattern of activity.
Losavio
Bradley E
BE
Dept. of Neuroscience, Baylor College of Medicine, Houston, TX 77030, USA. blosavio@cns.bcm.tmc.edu
Reddy
G Duemani
GD
Colbert
Costa M
CM
Kakadiaris
Ioannis A
IA
Saggau
Peter
P
D000200:Action Potentials / Q000502:physiology*; D000818:Animals; D001921:Brain / Q000502:physiology*; D001931:Brain Mapping / Q000379:methods*; D002478:Cells, Cultured; D003198:Computer Simulation; D008856:Microscopy, Fluorescence / Q000379:methods*; D008959:Models, Neurological; D009415:Nerve Net / Q000502:physiology*; D009474:Neurons / Q000502:physiology*; D051381:Rats; D018511:Systems Integration