title: Hydrodynamic effects of the partial opening of a trileaflet valve.
abstract: Manufacturing process of medical grade silicon rubber trileaflet valves for VADs could propitiate important leaflet thickness variations which could result in partial opening of the valve and affect its hydrodynamic performance. The leaflets of a total of 10 valves were measured to assess its thickness variability. Two experiments were performed to asses the impact of the leaflets thickness variation under hypothetical situations. The first experiment was divided into three hypothetical cases. In each case either none, one or two leaflets of different valves were mechanically blocked, resembling possible critical working circumstances. The second experiment was intended to know how the variation on the leaflets thickness affects the hydrodynamic performance of the valves. The results demonstrated a significant variation on the leaflets thickness was found. As for the first experiment, a small variation on the hydrodynamic performance was found above 4 L/min flow rates and a slightly higher energy loss was found in one of the cases. As for the second experiment, the results showed that the variation of the leaflet thickness does not affect the general hydrodynamic performance of the valves. No relationship between the thickness variability and the hydrostatic performance of the valves was found.
authors.affiliation: Innovamédica S.A. de C.V., Mexico City, Mexico.
authors.forename: C
authors.initials: C
authors.lastname: Escobedo
authors.forename: F
authors.initials: F
authors.lastname: Tovar
authors.forename: A
authors.initials: A
authors.lastname: Vilá
authors.forename: J
authors.initials: J
authors.lastname: García
authors.forename: B
authors.initials: B
authors.lastname: Suárez
authors.forename: F
authors.initials: F
authors.lastname: Corona
authors.forename: E
authors.initials: E
authors.lastname: Sacristán
mesh_terms: D001672:Biocompatible Materials; D001698:Biomedical Engineering; D006353:Heart-Assist Devices / Q000706:statistics & numerical data; D006801:Humans; D006874:Hydrostatic Pressure; D066298:In Vitro Techniques; D008422:Materials Testing; D011474:Prosthesis Design; D012826:Silicone Elastomers
chemical_list: D001672:Biocompatible Materials; D012826:Silicone Elastomers