title: Body mass index in children with newly diagnosed inflammatory bowel disease: observations from two multicenter North American inception cohorts.
abstract: OBJECTIVE
  To conduct a systematic review of children with newly diagnosed inflammatory bowel disease (IBD) from 2 prospective inception cohorts to examine body mass index (BMI) status at presentation.
  
  
  METHODS
  Clinical, demographic, and BMI data were obtained from 783 patients with newly diagnosed IBD. National Health and Nutrition Examination Survey data for 2748 healthy children were used as a control.
  
  
  RESULTS
  Most children with Crohn's disease and ulcerative colitis had a BMI in the normative range (5%-84%). Low BMI (<5%) was seen in 22% to 24% of children with Crohn's disease and 7% to 9% of children with ulcerative colitis. Ten percent of children with Crohn's disease and 20% to 30% of children with ulcerative colitis had a BMI at diagnosis consistent with overweight or risk for overweight.
  
  
  CONCLUSIONS
  Children with IBD are affected by current population trends toward overweight. A significant subgroup of children with newly diagnosed IBD has a BMI categorized as overweight or at risk for overweight. Clinicians should be aware of possible IBD diagnosis in the presence increased BMI.
authors.affiliation: Department of Pediatrics, Medical College of Wisconsin, Milwaukee, WI 53226, USA. skuga@mcw.edu
authors.forename: Subra
authors.initials: S
authors.lastname: Kugathasan
authors.forename: Justin
authors.initials: J
authors.lastname: Nebel
authors.forename: Joseph A
authors.initials: JA
authors.lastname: Skelton
authors.forename: James
authors.initials: J
authors.lastname: Markowitz
authors.forename: David
authors.initials: D
authors.lastname: Keljo
authors.forename: Joel
authors.initials: J
authors.lastname: Rosh
authors.forename: Neal
authors.initials: N
authors.lastname: LeLeiko
authors.forename: David
authors.initials: D
authors.lastname: Mack
authors.forename: Anne
authors.initials: A
authors.lastname: Griffiths
authors.forename: Athos
authors.initials: A
authors.lastname: Bousvaros
authors.forename: Jonathan
authors.initials: J
authors.lastname: Evans
authors.forename: Adam
authors.initials: A
authors.lastname: Mezoff
authors.forename: Susan
authors.initials: S
authors.lastname: Moyer
authors.forename: Maria
authors.initials: M
authors.lastname: Oliva-Hemker
authors.forename: Anthony
authors.initials: A
authors.lastname: Otley
authors.forename: Mariann
authors.initials: M
authors.lastname: Pfefferkorn
authors.forename: Wallace
authors.initials: W
authors.lastname: Crandall
authors.forename: Robert
authors.initials: R
authors.lastname: Wyllie
authors.forename: Jeffrey
authors.initials: J
authors.lastname: Hyams
mesh_terms: D000293:Adolescent; D015992:Body Mass Index; D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D006801:Humans; D015212:Inflammatory Bowel Diseases / Q000175:diagnosis / Q000453:epidemiology*; D009656:North America / Q000453:epidemiology; D050177:Overweight; D011446:Prospective Studies; D044469:Racial Groups / Q000706:statistics & numerical data; D012016:Reference Values; D012042:Registries