[The irradiation consequencees of animals with alloxan-induced diabetes].
The effects of external acute irradiation at dose 1.0 Gy on biologic, haematologic and metabolic changes in blood of alloxan-induced diabetic rats were studied. It was found that the deterioration of diabetic animals occurs in different terms after irradiation exposure, resulting in considerable body weight decrease, well-marked hyperglycemia, abrupt falling of leukocytic system parameters, intensification energetic processes of extant lymphocytes, imbalance of lipid metabolism and thyroid state, as well as significant inhibition of 5'-deiodinase activity in liver tissue.
Konoplia
E F
EF
Vereshchako
G G
GG
Gorokh
G A
GA
Andronov
E V
EV
Luk'ianenko
O V
OV
D000496:Alloxan / Q000633:toxicity; D000818:Animals; D001835:Body Weight / Q000528:radiation effects; D003921:Diabetes Mellitus, Experimental / Q000150:complications*; D005720:Gamma Rays / Q000009:adverse effects*; D007453:Iodide Peroxidase / Q000037:antagonists & inhibitors / Q000528:radiation effects; D007958:Leukocyte Count; D007962:Leukocytes / Q000528:radiation effects; D050356:Lipid Metabolism / Q000528:radiation effects; D008055:Lipids / Q000097:blood; D008297:Male; D011833:Radiation Injuries, Experimental / Q000097:blood / Q000150:complications / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains; D013961:Thyroid Gland / Q000528:radiation effects; D013974:Thyroxine / Q000097:blood; D014284:Triiodothyronine / Q000097:blood
D008055:Lipids; D014284:Triiodothyronine; D000496:Alloxan; D007453:Iodide Peroxidase; D013974:Thyroxine