title: [Lacunar infarction in brain tumor patients: chronic stage complication after radiation therapy].
abstract: The authors reported two relatively young adults with lacunar infarction that took place many years after radiation therapy. The first case was that of a 41-year-old male presenting with a slight decrease in consciousness and right hemiparesis of sudden occurrence. MRI revealed a lacunar infarction in the left internal capsule. This patient had received radiation therapy and chemotherapy for a right basal ganglia germinoma when he was 24 years old. The tumor completely disappeared and he was able to return to work. The second case was a 24-year-old female presenting with dysesthesia in the right upper extremity and nausea of sudden occurrence. MRI disclosed a lacunar infarct in the right corona radiata. The patient had received radiation therapy for a suprasellar tumor when she was 11 years old. The tumor considerably decreased in size and the patient conducted normal social life thereafter. MRI showed a lacunar infarction in the right corona radiata. Review of the literature was made and the possibility of radiation therapy as a causative factor of the lacunar infarction in relatively young adults was discussed.
authors.affiliation: Department of Neurosurgery, Brain Attack Center Ota Memorial Hospital, 3-6-28 Okinogami-cho, Fukuyama-shi, Hiroshima 720-0825, Japan.
authors.forename: Kiyoshi
authors.initials: K
authors.lastname: Nakazaki
authors.forename: Shirou
authors.initials: S
authors.lastname: Titoku
authors.forename: Shinzou
authors.initials: S
authors.lastname: Ota
authors.forename: Mitiyoshi
authors.initials: M
authors.lastname: Sato
authors.forename: Satoshi
authors.initials: S
authors.lastname: Kobanawa
authors.forename: Kazuyuki
authors.initials: K
authors.lastname: Tutida
authors.forename: Yasue
authors.initials: Y
authors.lastname: Tanaka
authors.forename: Katsuya
authors.initials: K
authors.lastname: Goto
authors.forename: Taisei
authors.initials: T
authors.lastname: Ota
mesh_terms: D000328:Adult; D000367:Age Factors; D020520:Brain Infarction / Q000175:diagnosis / Q000209:etiology*; D001932:Brain Neoplasms / Q000532:radiotherapy*; D005260:Female; D018237:Germinoma / Q000532:radiotherapy*; D020786:Hemangioma, Cavernous, Central Nervous System / Q000532:radiotherapy*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D011878:Radiotherapy / Q000009:adverse effects*; D013997:Time Factors