title: Selective enzymatic reduction of aldehydes.
abstract: Highly selective enzymatic reductions of aldehydes to the corresponding alcohols was performed using an E. coli JM109 whole cell biocatalyst. A selective enzymatic method for the reduction of aldehydes could provide an eco-compatible alternative to chemical methods. The simplicity, fairly wide scope and the very high observed chemoselectivity of this approach are its most unique features.
authors.affiliation: Dipartimento di Chimica Organica e Industriale, Università degli Studi di Milano, via Venezian 21, 20133 Milano, Italy. guido.sello@unimi.it
authors.forename: Guido
authors.initials: G
authors.lastname: Sello
authors.forename: Fulvia
authors.initials: F
authors.lastname: Orsini
authors.forename: Silvana
authors.initials: S
authors.lastname: Bernasconi
authors.forename: Patrizia
authors.initials: P
authors.lastname: Di Gennaro
mesh_terms: D000447:Aldehydes / Q000378:metabolism*; D002384:Catalysis; D004798:Enzymes / Q000378:metabolism*; D004926:Escherichia coli / Q000201:enzymology; D010084:Oxidation-Reduction
chemical_list: D000447:Aldehydes; D004798:Enzymes