Novel arylhydrazone-conjugated gold nanoparticles with DNA-cleaving ability: the first DNA-nicking nanomaterial.
Arylhydrazones were linked onto gold nanoparticles through the poly(ethylene glycol) spacer to produce a new type of photoinduced DNA-cleaving nanomaterials with great potency.
Hsu
Ming-Hua
MH
Department of Chemistry, National Tsing Hua University, Hsinchu, Taiwan, ROC.
Josephrajan
Thainashmuthu
T
Yeh
Chen-Sheng
CS
Shieh
Dar-Bin
DB
Su
Wu-Chou
WC
Hwu
Jih Ru
JR
D004247:DNA / Q000737:chemistry* / Q000378:metabolism; D053904:DNA Breaks, Single-Stranded; D006046:Gold / Q000737:chemistry*; D006834:Hydrazines / Q000737:chemistry*; D046529:Microscopy, Electron, Transmission; D015394:Molecular Structure; D053758:Nanoparticles / Q000737:chemistry* / Q000648:ultrastructure
D006834:Hydrazines; C029424:hydrazine; D006046:Gold; D004247:DNA