Leopold Ordenstein: on paralysis agitans and multiple sclerosis.
In 1868 the German Leopold Ordenstein (1835-1902) published in Paris a doctoral thesis in French language under the patronage of Jean-Martin Charcot (1825-1893). For the first time, multiple sclerosis and Parkinson's disease were clearly recognized as different clinical entities, based on clinical and pathological data. Ordenstein's work represents today a fundamental and often credited, yet still widely unknown, contribution to the history of these two diseases. The present paper delivers a synopsis of this key document. In addition, the life and work of Leopold Ordenstein will be reviewed.
Lehmann
H C
HC
Department of Neurology, Heinrich-Heine-University Duesseldorf, Germany. helmar.lehmann@uni-duesseldorf.de
Hartung
H-P
HP
Kieseier
B C
BC
D005858:Germany; D049672:History, 19th Century; D006801:Humans; D009103:Multiple Sclerosis / Q000266:history*; D010300:Parkinson Disease / Q000266:history*; D013782:Textbooks as Topic / Q000266:history