title: Resolution of superior oblique myokymia with memantine.
abstract: We describe a novel treatment of superior oblique myokymia. A 40-year-old woman was treated with gabapentin for this disorder with partial success and reported significant side effects including loss of libido and weight gain. After a drug holiday, memantine therapy was initiated resulting in a substantial improvement in her symptoms with far fewer side effects and stability on long-term maintenance therapy.
authors.affiliation: Leicester Royal Infirmary, Leicester, United Kingdom.
authors.forename: Saurabh
authors.initials: S
authors.lastname: Jain
authors.forename: Shegufta J
authors.initials: SJ
authors.lastname: Farooq
authors.forename: Irene
authors.initials: I
authors.lastname: Gottlob
mesh_terms: D000284:Administration, Oral; D000328:Adult; D003937:Diagnosis, Differential; D015259:Dopamine Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D004305:Dose-Response Relationship, Drug; D005133:Eye Movements; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008279:Magnetic Resonance Imaging; D008559:Memantine / Q000008:administration & dosage / Q000627:therapeutic use*; D020385:Myokymia / Q000175:diagnosis / Q000188:drug therapy* / Q000503:physiopathology; D015835:Ocular Motility Disorders / Q000175:diagnosis / Q000188:drug therapy* / Q000503:physiopathology; D009801:Oculomotor Muscles / Q000503:physiopathology*
chemical_list: D015259:Dopamine Agents; D008559:Memantine