Radioactive iodine therapy in poorly differentiated thyroid cancer.
BACKGROUND
A 55-year-old male was diagnosed with poorly differentiated thyroid cancer after total thyroidectomy, which was performed because of progressive enlargement of a dominant thyroid nodule. He developed an early cervical recurrence that was treated with modified neck dissection. He subsequently developed biopsy-proven progressive pulmonary metastases.


METHODS
Neck and chest CT scans, laboratory tests, CT-guided fine-needle aspiration biopsy, [18F]-2-fluoro-2-deoxy-D-glucose-PET scan, lesional dosimetry using 124I PET scan, diagnostic radioactive iodine (RAI) scanning, whole-body and blood RAI dosimetry, and single-photon-emission CT.


METHODS
Stage IV poorly differentiated thyroid cancer.


RESULTS
Surgical resection of cervical recurrence, RAI therapy.
Tuttle
R Michael
RM
Department of Radiology, Memorial Hospital, Weill Medical College of Cornell University New York, NY, USA. tuttlem@mskcc.org
Grewal
Ravinder K
RK
Larson
Steve M
SM
D002277:Carcinoma / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000532:radiotherapy / Q000556:secondary; D003937:Diagnosis, Differential; D006801:Humans; D007457:Iodine Radioisotopes / Q000627:therapeutic use*; D008175:Lung Neoplasms / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000532:radiotherapy* / Q000556:secondary; D008297:Male; D008875:Middle Aged; D009362:Neoplasm Metastasis; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000532:radiotherapy* / Q000556:secondary; D009367:Neoplasm Staging; D011859:Radiography; D019275:Radiopharmaceuticals / Q000627:therapeutic use*; D013964:Thyroid Neoplasms / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000473:pathology / Q000532:radiotherapy*
D007457:Iodine Radioisotopes; D019275:Radiopharmaceuticals