title: Electrical isolation during radiofrequency ablation: 5% dextrose in water provides better protection than saline.
abstract: We quantify the ability of 0.9% NaCl (saline) and 5% dextrose in water (D5W) to protect tissues during RF ablation. Using computer simulations and phantom experiments, we determined that D5W provides significantly more electrical isolation than saline, which reduces unwanted heating of the adjacent tissue. Saline actually increased the amount of RF current in the adjacent tissue. Based on these results, we conclude that D5W is preferable to saline as a protective fluid.
authors.affiliation: Department of Radiology, Wisconsin University, Madison, WI 53792, USA. clbrace@wisc.edu
authors.forename: Christopher L
authors.initials: CL
authors.lastname: Brace
authors.forename: Paul F
authors.initials: PF
authors.lastname: Laeseke
authors.forename: Vijay
authors.initials: V
authors.lastname: Prasad
authors.forename: Fred T
authors.initials: FT
authors.lastname: Lee
mesh_terms: D001698:Biomedical Engineering / Q000379:methods; D017115:Catheter Ablation / Q000295:instrumentation* / Q000379:methods; D003198:Computer Simulation; D017097:Electric Impedance; D004563:Electrochemistry / Q000379:methods; D004566:Electrodes; D004867:Equipment Design; D005947:Glucose / Q000494:pharmacology*; D008962:Models, Theoretical; D019047:Phantoms, Imaging; D012492:Salts / Q000494:pharmacology*; D012965:Sodium Chloride / Q000494:pharmacology; D013696:Temperature; D013997:Time Factors; D014867:Water / Q000737:chemistry*
chemical_list: D012492:Salts; D014867:Water; D012965:Sodium Chloride; D005947:Glucose