Metabolites from the endophytic fungus Phomopsis sp. PSU-D15.
From the endophytic fungus Phomopsis sp. PSU-D15, three metabolites named as phomoenamide (1), phomonitroester (2) and deacetylphomoxanthone B (3), were isolated together with three known compounds, dicerandrol A (4), (1S,2S,4S)-p-menthane-1,2,4-triol (5) and uridine. Their structures were elucidated by spectroscopic methods. Phomoenamide (1) exhibited moderate in vitro antimycobacterial activity against Mycobacterium tuberculosis H37Ra.
Rukachaisirikul
Vatcharin
V
Department of Chemistry, Faculty of Science, Prince of Songkla University, Hat Yai, Songkhla 90112, Thailand. vatcharin.r@psu.ac.th
Sommart
Ubonta
U
Phongpaichit
Souwalak
S
Sakayaroj
Jariya
J
Kirtikara
Kanyawim
K
D000995:Antitubercular Agents / Q000737:chemistry / Q000378:metabolism* / Q000494:pharmacology; D001203:Ascomycota / Q000737:chemistry / Q000378:metabolism*; D009682:Magnetic Resonance Spectroscopy / Q000379:methods / Q000592:standards; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D009169:Mycobacterium tuberculosis / Q000187:drug effects; D012015:Reference Standards; D013237:Stereoisomerism; D014529:Uridine / Q000737:chemistry / Q000378:metabolism* / Q000494:pharmacology; D044004:Xanthones / Q000737:chemistry / Q000378:metabolism* / Q000494:pharmacology
D000995:Antitubercular Agents; D044004:Xanthones; C436329:dicerandrol A; D014529:Uridine