title: [Management of HCV-HIV patients].
abstract: Reciprocal interactions between Human Immunodeficiency Virus (HIV) and Hepatitis C Virus (HCV) are characterized by the absence of clear impact of HCV on HIV; by contrast, HIV markedly modified the natural history of HCV (high viral load, more severe liver disease) at least before the introduction of highly active antiretroviral therapies (HAART). HAART has completely modified the pattern of hepatic events in HIV infection and the liver disease is one of the leading causes of morbidity and mortality nowadays, reflecting several non-exclusive pathogenic processes that include drug-related hepatotoxicities, chronic hepatitis C infection, other liver diseases such as steatosis or non-alcoholic steato-hepatitis (NASH) and other liver diseases that are common in the setting of alcohol or drug abuse. The harmful impact of HIV underlines the need for improving:
authors.affiliation: Unité d'Hépatologie, Hôpital Cochin, 27 rue du Faubourg Saint-Jacques, 75014 Paris. stanislas.pol@cch.aphp.fr
authors.forename: Stanislas
authors.initials: S
authors.lastname: Pol
authors.forename: Patrice
authors.initials: P
authors.lastname: Cacoub
authors.forename: Gilles
authors.initials: G
authors.lastname: Pialoux
authors.forename: Yves
authors.initials: Y
authors.lastname: Benhamou
authors.forename: Philippe
authors.initials: P
authors.lastname: Halfon
authors.forename: Eric
authors.initials: E
authors.lastname: Rosenthal
authors.forename: Christian
authors.initials: C
authors.lastname: Perronne
mesh_terms: D000998:Antiviral Agents / Q000627:therapeutic use*; D005234:Fatty Liver / Q000209:etiology / Q000517:prevention & control; D005838:Genotype; D015658:HIV Infections / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy*; D006509:Hepatitis B / Q000517:prevention & control; D019698:Hepatitis C, Chronic / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy*; D006801:Humans; D016867:Immunocompromised Host
chemical_list: D000998:Antiviral Agents