Metabolic risks and effects of atypical antipsychotic treatment.
Weight gain and the associated increased risk of diabetes and cardiovascular disease may be problems for individuals who receive long-term treatment with atypical antipsychotics. Atypical antipsychotics differ in their propensity to cause obesity and other metabolic disturbances. If a patient gains substantial weight while taking atypical antipsychotics, the physician should consider switching him or her to a drug with a lower risk of weight gain. The physician should also address patient lifestyle issues such as a poor diet and lack of exercise.
Haupt
Dan W
DW
Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA.
Kane
John M
JM
D014150:Antipsychotic Agents / Q000009:adverse effects*; D001480:Basal Ganglia Diseases / Q000139:chemically induced* / Q000175:diagnosis; D004502:Education, Medical, Continuing; D006801:Humans; D009765:Obesity / Q000139:chemically induced*; D010349:Patient Compliance / Q000706:statistics & numerical data; D012307:Risk Factors; D012559:Schizophrenia / Q000188:drug therapy*
D014150:Antipsychotic Agents