Chiral resolutions of (9-anthryl)methoxyacetic acid and (9-anthryl)hydroxyacetic acid by capillary electrophoresis.
The resolutions of (9-anthryl)methoxyacetic acid (9AMAA) and (9-anthryl)hydroxyacetic acid (9AHAA) were performed by capillary electrophoresis using hydroxypropyl-beta-cyclodextrin (HP-beta-CD) as a chiral selector. Various factors affecting migration time and resolutions of these compounds were investigated with a run voltage of 20 kV, column temperature 20 degrees C and 20 mM Tris-H(3)PO(4) buffer (pH 6.5) containing 5 mM HP-beta-CD for 9AMAA, or 10 mM HP-beta-CD for 9AHAA, (+/-)-9AMAA and (+/-)-9AHAA were successfully separated at Rs 3.27 and 1.92, respectively.
Li
Bao-Lin
BL
School of Chemistry and Materials Science, Shaanxi Normal University, Southern Changan Road #199, Xi'an, Shangxi, China. baolinli@snnu.edu.cn
Zhang
Zhen-Guo
ZG
Du
Li-Li
LL
Wang
Wei
W
D000085:Acetates / Q000737:chemistry*; D019075:Electrophoresis, Capillary; D006016:Glycolates / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D013237:Stereoisomerism
D000085:Acetates; D006016:Glycolates; C031149:glycolic acid; C013598:methoxyacetic acid