title: Cerebral laterality in Turner syndrome: a critical review of the literature.
abstract: Turner syndrome (TS) is a genetic disorder in females characterized by the complete or partial absence of one X chromosome. Its most consistent physical features include short stature and ovarian dysgenesis. TS individuals demonstrate a characteristic neurocognitive profile involving weaknesses in visuospatial processing. The hypothesis of defective right hemisphere specialization has been offered to explain the visuospatial deficits in TS. In contrast, an alternative explanation proposes a more uniform dysfunction of the left and right hemispheres, based on findings of symmetrical abnormalities. This article presents an overview of the two hypotheses, along with relevant findings on hemispheric specialization with respect to TS. The impact of the genetic and hormonal mechanisms on the neurocognitive profile of TS is also discussed and directions for further empirical research are identified.
authors.affiliation: Laboratory of Motor Control and Learning, Department of Physical Education and Sport Sciences, Aristotle University of Thessaloniki, Greece.
authors.forename: M
authors.initials: M
authors.lastname: Ganou
authors.forename: G
authors.initials: G
authors.lastname: Grouios
mesh_terms: D001921:Brain / Q000503:physiopathology*; D002648:Child; D003072:Cognition Disorders / Q000175:diagnosis / Q000453:epidemiology; D007839:Functional Laterality / Q000502:physiology*; D006801:Humans; D009483:Neuropsychological Tests; D012720:Severity of Illness Index; D014424:Turner Syndrome / Q000453:epidemiology / Q000503:physiopathology*