Audiovisual temporal correspondence modulates human multisensory superior temporal sulcus plus primary sensory cortices.
The brain should integrate related but not unrelated information from different senses. Temporal patterning of inputs to different modalities may provide critical information about whether those inputs are related or not. We studied effects of temporal correspondence between auditory and visual streams on human brain activity with functional magnetic resonance imaging (fMRI). Streams of visual flashes with irregularly jittered, arrhythmic timing could appear on right or left, with or without a stream of auditory tones that coincided perfectly when present (highly unlikely by chance), were noncoincident with vision (different erratic, arrhythmic pattern with same temporal statistics), or an auditory stream appeared alone. fMRI revealed blood oxygenation level-dependent (BOLD) increases in multisensory superior temporal sulcus (mSTS), contralateral to a visual stream when coincident with an auditory stream, and BOLD decreases for noncoincidence relative to unisensory baselines. Contralateral primary visual cortex and auditory cortex were also affected by audiovisual temporal correspondence or noncorrespondence, as confirmed in individuals. Connectivity analyses indicated enhanced influence from mSTS on primary sensory areas, rather than vice versa, during audiovisual correspondence. Temporal correspondence between auditory and visual streams affects a network of both multisensory (mSTS) and sensory-specific areas in humans, including even primary visual and auditory cortex, with stronger responses for corresponding and thus related audiovisual inputs.
Noesselt
Toemme
T
UCL Institute of Cognitive Neuroscience, University College London, London WC1N 3AR, United Kingdom. toemme@med.ovgu.de
Rieger
Jochem W
JW
Schoenfeld
Mircea Ariel
MA
Kanowski
Martin
M
Hinrichs
Hermann
H
Heinze
Hans-Jochen
HJ
Driver
Jon
J
D000161:Acoustic Stimulation / Q000379:methods; D000328:Adult; D001307:Auditory Perception / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D010775:Photic Stimulation / Q000379:methods; D011597:Psychomotor Performance / Q000502:physiology*; D013003:Somatosensory Cortex / Q000502:physiology*; D013702:Temporal Lobe / Q000502:physiology*; D014796:Visual Perception / Q000502:physiology*