title: Epidemiology of inflammatory bowel disease in the Songpa-Kangdong district, Seoul, Korea, 1986-2005: a KASID study.
abstract: BACKGROUND
  Crohn's disease (CD) and ulcerative colitis (UC) are considered rare diseases in developing countries. We have evaluated the incidence and prevalence of CD and UC over time in a district of Seoul, Korea.
  
  
  METHODS
  A population-based study was performed from 1986 to 2005 in the Songpa-Kangdong district of Seoul. To recruit patients as completely as possible, multiple information sources, including all medical facilities in the study area and 3 referral centers nearby but outside the study area, were used.
  
  
  RESULTS
  During the 20-year study period, 138 incident cases of CD (102 men, 36 women) and 341 incident cases of UC (170 men, 171 women) were identified. For the 20-year period, the adjusted mean annual incidence rates of CD and UC per 100,000 inhabitants were 0.53 (95% CI 0.44-0.62) and 1.51 (95% CI 1.34-1.67), respectively. When analyzed by 5-year intervals, the mean annual incidence rates of CD and UC increased significantly, from 0.05 and 0.34 per 100,000 inhabitants, respectively, in 1986-1990 to 1.34 and 3.08 per 100,000 inhabitants, respectively, in 2001-2005. The adjusted prevalence rates of CD and UC per 100,000 inhabitants on December 31, 2005, were 11.24 (95% CI 9.29-13.18) and 30.87 (95% CI 27.47-34.27), respectively.
  
  
  CONCLUSIONS
  The incidence and prevalence of CD and UC in Seoul, Korea, are still low compared with those in Western countries, but are rapidly increasing.
authors.affiliation: Department of Medicine, University of Ulsan College of Medicine and Asan Medical Center, Seoul, Korea. sky@amc.seoul.kr
authors.forename: Suk-Kyun
authors.initials: SK
authors.lastname: Yang
authors.forename: Sungcheol
authors.initials: S
authors.lastname: Yun
authors.forename: Jin-Ho
authors.initials: JH
authors.lastname: Kim
authors.forename: Joon Yong
authors.initials: JY
authors.lastname: Park
authors.forename: Hak Yang
authors.initials: HY
authors.lastname: Kim
authors.forename: Young-Ho
authors.initials: YH
authors.lastname: Kim
authors.forename: Dong Kyung
authors.initials: DK
authors.lastname: Chang
authors.forename: Joo Sung
authors.initials: JS
authors.lastname: Kim
authors.forename: In Sung
authors.initials: IS
authors.lastname: Song
authors.forename: Jong Beom
authors.initials: JB
authors.lastname: Park
authors.forename: Eui-Ryun
authors.initials: ER
authors.lastname: Park
authors.forename: Kyung Jo
authors.initials: KJ
authors.lastname: Kim
authors.forename: Gyoo
authors.initials: G
authors.lastname: Moon
authors.forename: Soo Hyun
authors.initials: SH
authors.lastname: Yang
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D003093:Colitis, Ulcerative / Q000453:epidemiology* / Q000235:genetics / Q000473:pathology; D003424:Crohn Disease / Q000453:epidemiology* / Q000235:genetics / Q000473:pathology; D005260:Female; D006801:Humans; D015994:Incidence; D007723:Korea / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D015995:Prevalence