Emulsion macromonomer cross-linking. A preparative method for oxidation-responsive nanoparticles with a controlled network structure.
We here report on a preparative, template-based method for oxidation-responsive, poly(propylene sulfide) cross-linked nanoparticles. In this study we demonstrate that preformed, narrow polydispersity, and end-functional polysulfides can be dispersed to yield stable emulsions, which can then be converted into stable nanoparticles through photochemically initiated cross-linking. The nanoparticle size is substantially templated on that of the precursor emulsions; the nanoparticles bulk is an elastomeric material with a homogeneous cross-linking density. The nanoparticles show a peculiar, two-stage behavior upon exposure to oxidants, which is likely composed of a first agglomeration phase followed by swelling.
Kilcher
Giona
G
School of Pharmacy and Pharmaceutical Sciences, University of Manchester, Oxford Road, Manchester, United Kingdom.
Duckham
Craig
C
Tirelli
Nicola
N
D003432:Cross-Linking Reagents / Q000737:chemistry*; D020724:Elastomers / Q000737:chemistry; D004655:Emulsions; D053761:Nanocomposites / Q000737:chemistry*; D053758:Nanoparticles / Q000737:chemistry*; D016877:Oxidants / Q000494:pharmacology; D010084:Oxidation-Reduction; D010316:Particle Size; D011108:Polymers / Q000138:chemical synthesis*; D013055:Spectrophotometry, Infrared; D013440:Sulfides / Q000138:chemical synthesis*; D013499:Surface Properties
D003432:Cross-Linking Reagents; D020724:Elastomers; D004655:Emulsions; D016877:Oxidants; D011108:Polymers; D013440:Sulfides; C522256:poly(propylene sulfide)