title: [Application of entropy-based complex systems partition method in research on quantizing TCM syndrome diagnostic criteria of angina pectoris].
abstract: OBJECTIVE
  To establish the quantized criteria for TCM syndrome diagnosis of angina pectoris (AP) using the entropy-based complex systems partition method (EBCSPM).
  
  
  METHODS
  Four hundred and three AP patients were randomly assigned to two groups: the operation group (302 cases) and the examination group (101 cases). The symptomatic information of the patients was extracted using EBCSPM to make sure the contribution degree of each symptom to syndrome diagnosis, and the diagnostic threshold was established by the analysis of receiver operating characteristic curves (ROC).
  
  
  RESULTS
  The basic syndromes manifested during AP were collateral-qi stagnation, collateral-qi deficiency and stagnation, turbid phlegm, blood stasis, phlegm-heat, heat-fire, yin deficiency and yang deficiency, etc. Different symptoms contributed to syndrome diagnosis to different degrees and with different diagnostic thresholds, showing good sensitivity and specificity in the prospective verification on the 101 patients in the examination group.
  
  
  CONCLUSIONS
  EBCSPM is applicable for quantizing TCM diagnostic criteria, and the established criteria shows favorable diagnostic efficacy for TCM syndrome diagnosis of AP.
authors.affiliation: Medical Department, Yiling Hospital, Hebei Medical University, Shijiazhuang. jiatcm@163.com
authors.forename: Zhen-Hua
authors.initials: ZH
authors.lastname: Jia
authors.forename: Ye-Shuang
authors.initials: YS
authors.lastname: Li
authors.forename: Yi-Ling
authors.initials: YL
authors.lastname: Wu
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000787:Angina Pectoris / Q000175:diagnosis*; D003627:Data Interpretation, Statistical; D003937:Diagnosis, Differential; D001330:Electronic Data Processing; D019277:Entropy; D005260:Female; D006801:Humans; D008297:Male; D008516:Medicine, Chinese Traditional / Q000379:methods*; D008875:Middle Aged; D011446:Prospective Studies; D012107:Research Design; D012680:Sensitivity and Specificity; D013577:Syndrome