title: Natriuretic peptides in cardiovascular diseases.
abstract: The natriuretic peptide family comprises atrial natriuretic peptide (ANP), brain natriuretic peptide (BNP), C-type natriuretic peptide (CNP), dendroaspis natriuretic peptide (DNP), and urodilatin. The activities of natriuretic peptides and endothelins are strictly associated with each other. ANP and BNP inhibit endothelin-1 (ET-1) production. ET-1 stimulates natriuretic peptide synthesis. All natriuretic peptides are synthesized from polypeptide precursors. Changes in natriuretic peptides and endothelin release were observed in many cardiovascular diseases: e.g. chronic heart failure, left ventricular dysfunction and coronary artery disease.
authors.affiliation: Department of Anaesthesiology and Intensive Care Unit, Boleslaw Szarecki University Hospital No. 5 in Łódź, Medical University in Łódź, Łódź, Poland.
authors.forename: Mariusz
authors.initials: M
authors.lastname: Piechota
authors.forename: Maciej
authors.initials: M
authors.lastname: Banach
authors.forename: Anna
authors.initials: A
authors.lastname: Jacoń
authors.forename: Jacek
authors.initials: J
authors.lastname: Rysz
mesh_terms: D000595:Amino Acid Sequence; D002318:Cardiovascular Diseases / Q000235:genetics / Q000378:metabolism*; D016232:Endothelins / Q000378:metabolism; D006801:Humans; D008969:Molecular Sequence Data; D045265:Natriuretic Peptides / Q000737:chemistry / Q000378:metabolism*
chemical_list: D016232:Endothelins; D045265:Natriuretic Peptides