title: Semi-automated analysis of coronary flow Doppler images: validation with manual tracings.
abstract: Coronary flow velocity reserve (CFVR) is conventionally obtained by manual tracings of Doppler profiles, as ratio of stress vs baseline diastolic peak velocity. When <1.9, this parameter evidences reduced coronary flow and possible microcirculatory disease. Our goals were: 1) to develop a novel technique for semi-automated detection of Doppler flow velocity profile, allowing the automated computation of CFVR and other parameters; 2) to validate this technique in comparison with conventional measurements obtained by manual tracing; 3) to test for differences between normal (N) subjects and patients with rheumatoid arthritis (RA). Linear correlation and Bland-Altman analyses showed that the proposed method was highly accurate and repeatable compared to the manual measurements. Comparison between N and RA groups evidenced significant differences in some of the automated parameters.
authors.affiliation: Biomedical Engineering Dept., Polytechnic of Milan, Italy. valentina.magagnin@polimi.it
authors.forename: V
authors.initials: V
authors.lastname: Magagnin
authors.forename: E G
authors.initials: EG
authors.lastname: Caiani
authors.forename: L
authors.initials: L
authors.lastname: Delfino
authors.forename: C
authors.initials: C
authors.lastname: Champlon
authors.forename: S
authors.initials: S
authors.lastname: Cerutti
authors.forename: M
authors.initials: M
authors.lastname: Turiel
mesh_terms: D000465:Algorithms; D001172:Arthritis, Rheumatoid / Q000000981:diagnostic imaging*; D001185:Artificial Intelligence; D003324:Coronary Artery Disease / Q000000981:diagnostic imaging*; D003331:Coronary Vessels / Q000000981:diagnostic imaging*; D004452:Echocardiography / Q000379:methods*; D005260:Female; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D008297:Male; D008875:Middle Aged; D010363:Pattern Recognition, Automated / Q000379:methods*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity