title: Migraine and delayed ischaemic neurological deficit after subarachnoid haemorrhage in women: a case-control study.
abstract: The aim of the present case-control study was to investigate the role of migraine as a potential risk factor for a delayed ischaemic neurological deficit (DIND) after subarachnoid haemorrhage (SAH). A telephone interview was performed in patients or their relatives to determine the prevalence of migraine. Thirty-six women aged <60 years had SAH with Hunt & Hess grade I-III and DIND (group A). This group was compared with an age-matched group of 36 female SAH patients, Hunt & Hess grade I-III without DIND (group B). The two populations were also characterized regarding hypertension, smoking, diabetes mellitus and alcohol use. A significant difference was only found for the prevalence of migraine with 47% in group A and 25% in group B (P < 0.05; odds ratio: 2.68, confidence interval: 0.99-7.29). Migraineurs revealed similar prevalences of risk factors independently of the presence of DINDs. This retrospective study suggests that women with migraine have a higher risk to develop a DIND than women without migraine.
authors.affiliation: Department of Neurology, Charité University Medicine Berlin, Germany. jens.dreier@charite.de
authors.forename: J P
authors.initials: JP
authors.lastname: Dreier
authors.forename: C
authors.initials: C
authors.lastname: Kremer
authors.forename: G
authors.initials: G
authors.lastname: Lammers
authors.forename: F
authors.initials: F
authors.lastname: Lohmann
authors.forename: H C
authors.initials: HC
authors.lastname: Hansen
authors.forename: J M
authors.initials: JM
authors.lastname: Valdueza
mesh_terms: D000328:Adult; D000428:Alcohol Drinking / Q000453:epidemiology; D002545:Brain Ischemia / Q000453:epidemiology*; D016022:Case-Control Studies; D015897:Comorbidity; D003920:Diabetes Mellitus / Q000453:epidemiology; D005260:Female; D006801:Humans; D006973:Hypertension / Q000453:epidemiology; D007407:Interviews as Topic; D008875:Middle Aged; D008881:Migraine Disorders / Q000453:epidemiology*; D015995:Prevalence; D012189:Retrospective Studies; D012307:Risk Factors; D012737:Sex Factors; D012907:Smoking / Q000453:epidemiology; D013345:Subarachnoid Hemorrhage / Q000453:epidemiology*; D013997:Time Factors