Oxidative stress markers in pregnant women who snore and fetal outcome: a case control study.
BACKGROUND
To determine the levels of oxidative stress markers in pregnant women who snore and compare with non-snoring pregnant women. Fetal outcome of these 2 groups was also evaluated.


METHODS
Prospective, case control study. Some 40 pregnant women who snored and 43 non-snoring pregnant women were evaluated. The glutathione peroxidase (GSH-Px), malondialdehyde (MDA) and myeloperoxidase (MPO) levels of the 2 groups were studied. Infant birthweight, Apgar scores, and other indicators of fetal outcome were obtained.


RESULTS
The mean level of GSH-Px was significantly lower in the pregnant women who snored (p=0.005), while the mean level of MDA was significantly higher in this group (p=0.005). Levels of MPO were comparable between the groups (p>0.05). The pregnant women who snored did not have infants with evidence of an increase in compromised outcome.


CONCLUSIONS
Although the pregnant women who snored had high levels of MDA, they did not appear to be at increased risk for delivering infants with fetal compromise.
Köken
Gülengül
G
Department of Obstetrics and Gynecology, Medical Faculty, Afyon Kocatepe University, Afyonkarahisar, Turkey.
Sahin
Figen Kir
FK
Cosar
Emine
E
Saylan
Filiz
F
Yilmaz
Nigar
N
Altuntas
Irfan
I
Fidan
Fatma
F
Unlu
Mehmet
M
Yilmazer
Mehmet
M
D000328:Adult; D016022:Case-Control Studies; D005260:Female; D005979:Glutathione Peroxidase / Q000097:blood*; D006801:Humans; D007231:Infant, Newborn; D008315:Malondialdehyde / Q000097:blood*; D018384:Oxidative Stress / Q000502:physiology*; D009195:Peroxidase / Q000097:blood*; D011247:Pregnancy; D011248:Pregnancy Complications / Q000378:metabolism*; D011256:Pregnancy Outcome; D020181:Sleep Apnea, Obstructive / Q000378:metabolism; D012913:Snoring / Q000378:metabolism*
D008315:Malondialdehyde; D009195:Peroxidase; D005979:Glutathione Peroxidase