Immunoglobulin A pemphigus involving the perianal skin and oral mucosa: an unusual presentation.
Immunoglobulin A (IgA) pemphigus is a rare autoimmune blistering disease characterized by epidermal acantholysis and neutrophilic infiltrates, as well as intraepidermal IgA deposits. We report an unusual case of IgA pemphigus involving anal/ perianal skin and oral mucosa that demonstrated a successful response to dapsone treatment.
Erdag
Gulsun
G
Department of Pathology, Georgetown University Medical Center, Washington, DC 20007, USA. gulsun_erdag@yahoo.com
Qureshi
Hina S
HS
Greer
Kenneth E
KE
Patterson
James W
JW
D000890:Anti-Infective Agents / Q000627:therapeutic use; D001004:Anus Diseases / Q000188:drug therapy / Q000276:immunology* / Q000473:pathology; D001324:Autoantigens / Q000097:blood; D003622:Dapsone / Q000627:therapeutic use; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D007070:Immunoglobulin A / Q000276:immunology*; D008875:Middle Aged; D009061:Mouth Mucosa / Q000276:immunology* / Q000473:pathology; D010392:Pemphigus / Q000188:drug therapy / Q000276:immunology* / Q000473:pathology; D011241:Prednisone / Q000627:therapeutic use
D000890:Anti-Infective Agents; D001324:Autoantigens; D005938:Glucocorticoids; D007070:Immunoglobulin A; D003622:Dapsone; D011241:Prednisone