Growth and neurodevelopment outcome of very low birth weight infants delivered by preeclamptic mothers.
OBJECTIVE
To investigate growth and neurodevelopment outcome of very low birth weight (VLBW) infants delivered by preeclamptic mothers.


METHODS
A cohort including all VLBW infants delivered between December 2003 and May 2005 was followed up to 12 and 18 months corrected age (CA).


METHODS
death before 1 year corrected age, major malformations, deafness and blindness. Weight, length and head circumference were plotted on NCHS curves. Bayley Scales were performed at 12 and 18 months CA.


RESULTS
40 infants in preeclamptic and 46 in control groups were studied. Birth weight and gestational age were 1148 g+/-236 and 1195 g+/-240, and 31.3 weeks+/-1 and 30.6 weeks+/-2 for preeclamptic and control groups, respectively. At 12 and 18 months, CA, weight for age (Z score) was significantly higher in control than in preeclamptic. PDI scores were higher in preeclamptic than in controls at 18 months CA.


CONCLUSIONS
Catch-up of body weight did not occur in the first 18 months CA in preeclamptic infants. Neurodevelopment outcome was better in infants delivered by preeclamptic mothers than in controls at 18 months CA.
Silveira
Rita C
RC
Department of Pediatrics, Newborn Section, Universidade Federal do Rio Grande do Sul, and Hospital de Clínicas de Porto Alegre, Porto Alegre, RS, Brazil.
Procianoy
Renato S
RS
Koch
Maike S
MS
Benjamin
Ana Cláudia W
AC
Schlindwein
Carolina F
CF
D000704:Analysis of Variance; D049628:Body Size; D016022:Case-Control Studies; D002508:Cephalometry; D015331:Cohort Studies; D002658:Developmental Disabilities / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology*; D005260:Female; D005317:Fetal Growth Retardation / Q000503:physiopathology / Q000523:psychology; D005865:Gestational Age; D006130:Growth Disorders / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D019102:Infant, Very Low Birth Weight / Q000254:growth & development*; D011225:Pre-Eclampsia; D011247:Pregnancy; D011446:Prospective Studies; D011596:Psychomotor Disorders / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology*; D012307:Risk Factors; D018709:Statistics, Nonparametric