A portable needle-free jet injector based on a custom high power-density voice-coil actuator.
We have constructed a portable needle-free drug injection (NFI) device based upon a custom voice-coil linear actuator. Our actuator is optimized to provide high instantaneous force (>200 N) and power (4 kW) while still allowing a total stroke of 25 mm. The actuator is relatively inexpensive, compact, and lightweight, allowing it to serve as the force generator in a portable, reusable, handheld NFI system. The actuator is capable of accelerating liquid drug in quantities of up to 250 microL to a speed of more than 200 ms(-1). The repeatability of a 50 microL volume ejection is better than +/-1 microL.
Taberner
Andrew J
AJ
Bioinstrumentation Lab, Mechanical Engineering Department, Massachusetts Institute of Technology, Cambridge, MA 02139, USA. taberner@mit.edu
Ball
Nathan B
NB
Hogan
N Catherine
NC
Hunter
Ian W
IW
D004396:Coloring Agents / Q000494:pharmacology; D016503:Drug Delivery Systems; D011211:Electric Power Supplies; D004867:Equipment Design; D007277:Injections, Jet; D007279:Injections, Subcutaneous; D008280:Magnetics; D015233:Models, Statistical; D009339:Needles; D011312:Pressure; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D012869:Skin Absorption; D013594:Syringes; D014831:Voice
D004396:Coloring Agents