[Clinical characteristics of Behcet's disease with cardiac involvement - an analysis of forty-two cases].
OBJECTIVE
To analyze the clinical characteristics of Behcet's disease with cardiac involvement.


METHODS
Patients diagnosed as Behcet's disease with cardiac involvement in Peking Union Medical College Hospital from 1990 to 2006 were included in this analysis. The clinical characteristics of these patients were studied retrospectively.


RESULTS
Forty-two patients were included. Cardiac involvement included valvular disease, angina, pericardial effusion, arrhythmia, intracardiac thrombus and pulmonary artery hypertension. The effect of valve replacement or intervention treatment was related to the activity of Behcet's disease. The involvement of pulmonary artery was an independent correlative factor of mortality (P = 0.03).


CONCLUSIONS
The manifestation of cardiac involvement in Behcet's disease is various. If needed, valve replacement operation and intervention treatment should be performed when the Behcet's disease is stable. The involvement of pulmonary artery is an independent correlative factor of mortality.
Liu
Yong-tai
YT
Department of Cardiology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China. ataiever@163.com
Tian
Zhuang
Z
Fang
Li-gang
LG
Zeng
Xiao-feng
XF
D000328:Adult; D001528:Behcet Syndrome / Q000150:complications / Q000175:diagnosis* / Q000628:therapy; D005260:Female; D005500:Follow-Up Studies; D006331:Heart Diseases / Q000175:diagnosis* / Q000209:etiology / Q000628:therapy; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies