title: Knee joint synovitis in Behçet's disease: a sonographic study.
abstract: OBJECTIVE
  The aim of this study was to investigate, using ultrasound (US), knee involvement in patients with Behçet's disease (BD).
  
  
  METHODS
  Knee US was performed in 30 unselected Italian BD patients. Signs of arthritis (joint effusion, synovial proliferation) and presence of bone erosions and Baker's cysts were recorded. Power Doppler evaluation was performed. A semi-quantitative score was used for each structure examined, whereby 0 was to indicate the absence of any change and score from 1 to 3 the presence of mild to severe changes. A sum of the single scores was obtained. Disease activity was evaluated to identify the correlation with the US modifications.
  
  
  RESULTS
  Twenty (66.6%) patients had symptomatic articular involvement and US showed knee involvement in 18 of them (60%). Synovial proliferation was detected in 14 (46%, positive power Doppler in 4), joint effusion in 14 (46%), bone surface erosions in 3 (10%). Four patients, asymptomatic for joint involvement, showed US alterations. Eleven patients showed a total score between 1 and 3, while the other 7 had a score between 4 and 6. Subjects with a higher US score presented an increased prevalence of acneiform skin lesions with respect to the group with US score 1-3. Statistical analysis showed a positive correlation between disease activity and US score in group 2 (p=0.04).
  
  
  CONCLUSIONS
  This study confirms that peripheral joint involvement represents an important clinical aspect in italian BD patients and US evaluation is useful for the detection of this aspect.
authors.affiliation: Divisione e Cattedra di Reumatologia, Dipartimento di Scienze Oftalmiche, Università "La Sapienza", Roma, Italy.
authors.forename: F
authors.initials: F
authors.lastname: Ceccarelli
authors.forename: R
authors.initials: R
authors.lastname: Priori
authors.forename: A
authors.initials: A
authors.lastname: Iagnocco
authors.forename: G
authors.initials: G
authors.lastname: Coari
authors.forename: M
authors.initials: M
authors.lastname: Accorinti
authors.forename: P
authors.initials: P
authors.lastname: Pivetti Pezzi
authors.forename: G
authors.initials: G
authors.lastname: Valesini
mesh_terms: D000328:Adult; D000368:Aged; D001168:Arthritis / Q000000981:diagnostic imaging; D001528:Behcet Syndrome / Q000473:pathology*; D015331:Cohort Studies; D005260:Female; D006801:Humans; D007719:Knee Joint / Q000000981:diagnostic imaging / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D012720:Severity of Illness Index; D013582:Synovial Fluid / Q000000981:diagnostic imaging; D013585:Synovitis / Q000000981:diagnostic imaging / Q000473:pathology*; D014463:Ultrasonography