Novel and efficient synthesis of N,N-dialkylaminoand O-alkylphenyl-2-(1-alkyl/phenyl-2-oxopropylidene) phosphonohydrazido oximes--potential marine fish toxin analogues. Part 2.
A novel and efficient method for the synthesis of N,N-dialkylamino/O-alkyl phenyl-2-(1-alkyl/phenyl-2-oxopropylidene) phosphonohydrazido oximes 4 using activated silica has been developed. The reaction involves the condensation of substituted alpha-ketooxime and N,N-dialkylaminophenylphosphonohydrazides or O-alkylphenylphosphonohydrazides and gave the corresponding phosphonohydrazido oximes in excellent yields under mild conditions.
Kumar
Rajesh
R
Process Technology Development Division, Defence R and D Establishment, Jhansi Road, Gwalior-474002 (MP), India.
Gupta
Arvind K
AK
Kaushik
Mahabir P
MP
D000818:Animals; D005399:Fishes; D008387:Marine Toxins / Q000138:chemical synthesis / Q000737:chemistry* / Q000633:toxicity; D010091:Oximes / Q000138:chemical synthesis* / Q000737:chemistry / Q000633:toxicity
D008387:Marine Toxins; D010091:Oximes