[Discussion on pharmacological mechanism of laosun kangfu tablets].
OBJECTIVE
to study pharmacological mechanism of Laosun Kangfu tablet.


METHODS
Blood-activating and stasis-removing was tested by establishing cute cold pathogens induced blood stasis rat model and microcirculation disturbance state rat model by means of dripping adrenine on the mensentery. The resisting oxidation was tested by establishing the freely falling body damages models. The kidney-notifying was tested by Acetic acid hydrocortisone-caused kidney asthenia of mice.


RESULTS
All of the experimental results showed that there were Significant differences between the treatment groups and the control groups, such as promoting blood circulation and removing blood stasis, resisting the oxidation, the kidney-notifying actions.


CONCLUSIONS
Effects of Huoxue Xiaozhong and Xingqi Zhitong of Laosun Kangfu tablet is because the action of improving microcirculation, antioxidation and regulating endocrine.
Cheng
Jia-yi
JY
Liaoning University of Traditional Chinese Medicine, Shenyang 110032, China. cjy.61@163.com
Yan
Xing-yu
XY
Yang
Jing-ling
JL
D000818:Animals; D001809:Blood Viscosity / Q000187:drug effects; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification / Q000494:pharmacology*; D004906:Erythrocyte Count; D005260:Female; D006854:Hydrocortisone / Q000097:blood; D008297:Male; D008315:Malondialdehyde / Q000097:blood; D008516:Medicine, Chinese Traditional; D051379:Mice; D008833:Microcirculation / Q000187:drug effects; D010946:Plants, Medicinal / Q000737:chemistry*; D051381:Rats; D017208:Rats, Wistar; D013152:Splanchnic Circulation / Q000187:drug effects*; D013482:Superoxide Dismutase / Q000097:blood; D013607:Tablets
D004338:Drug Combinations; D004365:Drugs, Chinese Herbal; D013607:Tablets; D008315:Malondialdehyde; D013482:Superoxide Dismutase; D006854:Hydrocortisone