title: Pre-SAT180, a simple and effective method for residual water suppression.
abstract: Water located outside the NMR detection coil experiences a reduced RF field intensity. This "faraway water" is known to be very difficult to suppress and often gives rise to a large residual solvent signal. Pre-SAT180 (Pre-Saturation with Adiabatic Toggling of 180 degree pulse inversion) is proposed to cancel the residual water contribution efficiently. Compared with several popular methods such as 1D NOESY with pre-saturation or 270 degrees excitation, Pre-SAT180 has a number of advantages, including: full retention of signal intensity and selectivity, good phase properties, easy setup, and high tolerance to pulse missettings.
authors.affiliation: Purdue Inter-Departmental NMR Facility, Purdue University, West Lafayette, IN 47907, USA. hmo@purdue.edu
authors.forename: Huaping
authors.initials: H
authors.lastname: Mo
authors.forename: Daniel
authors.initials: D
authors.lastname: Raftery
mesh_terms: D001834:Body Water / Q000378:metabolism*; D006801:Humans; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D012815:Signal Processing, Computer-Assisted; D014556:Urine / Q000737:chemistry*