Apneic seizures: a sign of temporal lobe hemorrhage in full-term neonates.
Intracranial hemorrhage is a common cause of neonatal seizures in full-term infants. However, only some infants with intracranial hemorrhage come to clinical attention. A right temporal lobe hemorrhage with resulting apneic seizures was described previously in one neonate. In this case report, we review three full-term male neonates with no significant perinatal complications who presented with apneic events and temporal lobe hemorrhage. One neonate had apnea as the sole manifestation of a seizure that was confirmed electrographically. One neonate had motor manifestations of seizures, in addition to apnea, that were confirmed as seizures electrographically. The third neonate had pure apneic events before initiation of electroencephalogram monitoring which were presumed to be seizures, because the electroencephalogram demonstrated epileptiform abnormalities. At follow-up, all three children were neurodevelopmentally normal. This case report emphasizes that, although uncommon, full-term neonates may present with apnea as the initial manifestation of temporal lobe hemorrhage. Because apnea could be a manifestation of a seizure, continuous electroencephalogram monitoring should be considered in a full-term neonate with unexplained apnea.
Sirsi
Deepa
D
Department of Pediatric Neurology, New York Presbyterian Hospital, Weill Cornell Medical College, New York, New York 10021, USA.
Nadiminti
Lakshmi
L
Packard
Maurine A
MA
Engel
Murray
M
Solomon
Gail E
GE
D001049:Apnea / Q000209:etiology*; D002543:Cerebral Hemorrhage / Q000150:complications* / Q000473:pathology*; D004569:Electroencephalography / Q000379:methods; D006801:Humans; D007231:Infant, Newborn; D008279:Magnetic Resonance Imaging; D008297:Male; D012640:Seizures / Q000209:etiology*; D013702:Temporal Lobe / Q000503:physiopathology*