title: Fatal hemorrhagic intracranial TB in a renal transplant recipient despite INH prophylaxis.
abstract: A 50-year-old ESRD who received LUR renal graft abroad. Since transplanted, he remained dependent on hemodialysis. The patient received steroid pulse therapy twice for rejecrion. Nonspecific bilateral lung infiltrate were noted on admission CXR, which stimulated the search for TB. The patient suddenly lost consciousness during his hospital stay. Intracranial hemorrhage was drained and tissue staining revealed heavy loads of tuberculus (TB) bacilli. The patient died two weeks later from septic shock with multi-organ failure.
authors.affiliation: Department of Nephrology, North West Armed Forces Hospital, Tabuk, Saudi Arabia.
authors.forename: Nasrulla
authors.initials: N
authors.lastname: Abutaleb
authors.forename: Abdulmunaem
authors.initials: A
authors.lastname: Obaideen
authors.forename: Abdulmajeed
authors.initials: A
authors.lastname: Hamza
authors.forename: M
authors.initials: M
authors.lastname: Zakaria
authors.forename: Hisham
authors.initials: H
authors.lastname: Afifi
authors.forename: Sammera
authors.initials: S
authors.lastname: Fallata
authors.forename: Seddiq
authors.initials: S
authors.lastname: Younis
authors.forename: Muhalab
authors.initials: M
authors.lastname: Adem
mesh_terms: D000995:Antitubercular Agents / Q000627:therapeutic use*; D017809:Fatal Outcome; D005500:Follow-Up Studies; D006801:Humans; D020300:Intracranial Hemorrhages / Q000175:diagnosis / Q000209:etiology*; D007538:Isoniazid / Q000627:therapeutic use*; D007676:Kidney Failure, Chronic / Q000601:surgery*; D016030:Kidney Transplantation; D008297:Male; D008875:Middle Aged; D013902:Radiography, Thoracic; D016862:Tuberculoma, Intracranial / Q000150:complications* / Q000175:diagnosis / Q000517:prevention & control; D014397:Tuberculosis, Pulmonary / Q000150:complications / Q000175:diagnosis / Q000517:prevention & control
chemical_list: D000995:Antitubercular Agents; D007538:Isoniazid