[Evaluation of the vaccine potentiality of 2 strains from Leptospira interrogans serogroup Ballum].
Two vacine candidate strains from Ballum serogroup were characterized and their immunogenicity and protective power were studied in hamster. The monovalent vaccine formulations obtained showed a high immunogenicity and capacity of homologous protection and, in a lesser degree, of cross protection.
Rodríguez
Andrés González
AG
Instituto Finlay, Centro de Investigación y Producción de Vacunas, Ciudad de La Habana, Cuba. andresglez@finlay.edu.cu
Jiménez
Yoandra Rodríguez
YR
Santiesteban
Niurka Batista
NB
Abreu
Yolanda Valdés
YV
Osenes
Juan Francisco Núñez
JF
González
Marta González
MG
D000818:Animals; D001428:Bacterial Vaccines / Q000008:administration & dosage / Q000276:immunology*; D006224:Cricetinae; D004195:Disease Models, Animal; D004797:Enzyme-Linked Immunosorbent Assay; D006801:Humans; D007921:Leptospira interrogans / Q000276:immunology*; D041341:Leptospira interrogans serovar canicola / Q000276:immunology; D041383:Leptospira interrogans serovar icterohaemorrhagiae / Q000276:immunology; D041401:Leptospira interrogans serovar pomona / Q000276:immunology; D007922:Leptospirosis / Q000517:prevention & control*; D013997:Time Factors; D014895:Weil Disease / Q000517:prevention & control
D001428:Bacterial Vaccines