Hypoplasminogenaemia, gingival swelling and ulceration.
This article reviews the evolution of the history related to an unusual type of generalized gingival swelling we first described in a single adult British patient; then recognized by us and others in small cohorts in Turkey; later found in several countries worldwide. We finally recognized it to represent the oral manifestations of plasminogen deficiency (hypoplasminogenaemia).
Scully
C
C
Eastman Dental Institute, University College London, London, UK. c.scully@eastman.ucl.ac.uk
Gokbuget
A
A
Kurtulus
I
I
D000933:Antifibrinolytic Agents / Q000009:adverse effects; D005882:Gingival Diseases / Q000209:etiology* / Q000473:pathology / Q000628:therapy; D005885:Gingival Hyperplasia / Q000235:genetics; D006801:Humans; D010958:Plasminogen / Q000172:deficiency*; D014148:Tranexamic Acid / Q000009:adverse effects
D000933:Antifibrinolytic Agents; D014148:Tranexamic Acid; D010958:Plasminogen