title: Integration of large-area polymer nanopillar arrays into microfluidic devices using in situ polymerization cast molding.
abstract: Presented here is a simple and robust approach for the integration of mixed-scale (nm-cm) structures into fluidic devices. We report on devices composed of large-area polymer nanopillar arrays of high aspect ratio (33-667) integrated into microfluidic channels fabricated by cast-molding polymerization of methyl methacrylate with mechanically/lithographically patterned, nanoporous aluminium oxide (AAO) templates. The microchannels containing the nanopillar arrays can be chemically functionalized and used for a variety of applications, such as separation beds or solid-phase reactors/extractors.
authors.affiliation: Department of Chemistry and Center for Biomodular Multiscale Systems, Louisiana State University, Baton Rouge, LA 70803-1804, USA. tunnel@lsu.edu
authors.forename: Guofang
authors.initials: G
authors.lastname: Chen
authors.forename: Gregory T
authors.initials: GT
authors.lastname: McCandless
authors.forename: Robin L
authors.initials: RL
authors.lastname: McCarley
authors.forename: Steven A
authors.initials: SA
authors.lastname: Soper
mesh_terms: D000537:Aluminum Oxide / Q000737:chemistry; D044085:Microfluidics / Q000295:instrumentation*; D008855:Microscopy, Electron, Scanning; D049329:Nanostructures; D011108:Polymers / Q000737:chemistry*
chemical_list: D011108:Polymers; D000537:Aluminum Oxide