[Choice reaction time (CRT) in humans after administration of lorazepam].
Eight normal subjects were tested on auditory and visual choice reaction time and Tapping-Speed Test before and after two hours by administration of lorazepam (2.5 mg per os). CRTs slightly increase but not significantly; Tapping-Speed Test does not show changes. Nevertheless a significant increase of errors in all trials suggest a moderate decrease of performance after lorazepam.
Lombardi
M
M
Clinica Neurologica dell'Università di Pavia.
Cosi
V
V
D000284:Administration, Oral; D000328:Adult; D014151:Anti-Anxiety Agents / Q000008:administration & dosage / Q000494:pharmacology*; D001307:Auditory Perception / Q000187:drug effects; D002755:Choice Behavior; D006801:Humans; D008140:Lorazepam / Q000008:administration & dosage / Q000494:pharmacology*; D008297:Male; D011597:Psychomotor Performance / Q000187:drug effects; D011930:Reaction Time / Q000187:drug effects*; D012016:Reference Values; D013997:Time Factors; D014796:Visual Perception / Q000187:drug effects
D014151:Anti-Anxiety Agents; D008140:Lorazepam