title: [Immunological response (IgM) to Legionella pneumophila infection in children].
abstract: Most of the publications report cases of Legionella infection among adults. In our studies the level of IgM to Legionella pneumophila sg 1 was determined by ELISA method in serum samples of 144 children with symptoms of respiratory tract infections. Children were from 5 months to 18 years old. The significant level of IgM was found in 41 sera collected from 34 children aged 2 years and above. There were samples collected from 21 girls and 13 boys. The highest percentage of significant level of IgM was found in the age group 4-10 years (31.8%) and 10-14 years (31.7%). Among the youngest children (below 2 years) the equivocal results were found in 6 samples. The significant difference in IgM level was found between the children age groups. There was not found the significant differences in IgM level depending on gender. Obtained results indicated the importance of such kind of studies and necessity of adjusting cut-off values to age groups of children.
authors.affiliation: Zakład Bakteriologii Państwowego Zakładu Higieny w Warszawie. kpancer@pzh.gov.pl
authors.forename: Katarzyna W
authors.initials: KW
authors.lastname: Pancer
authors.forename: Alicja
authors.initials: A
authors.lastname: Pawińska
authors.forename: Daniel
authors.initials: D
authors.lastname: Rabczenko
authors.forename: Justyna
authors.initials: J
authors.lastname: Milczewska
authors.forename: Joanna
authors.initials: J
authors.lastname: Friedman-Gruszczyńska
authors.forename: Janusz B
authors.initials: JB
authors.lastname: Ksiazyk
authors.forename: Danuta
authors.initials: D
authors.lastname: Dzierzanowska
authors.forename: Hanna
authors.initials: H
authors.lastname: Stypułkowska-Misiurewicz
mesh_terms: D000293:Adolescent; D000367:Age Factors; D002648:Child; D002675:Child, Preschool; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D007075:Immunoglobulin M / Q000097:blood*; D007223:Infant; D007877:Legionnaires' Disease / Q000097:blood / Q000276:immunology*; D008297:Male; D012141:Respiratory Tract Infections / Q000276:immunology* / Q000382:microbiology*
chemical_list: D007075:Immunoglobulin M