[Clinical expirience in the treatment of purulent meningitis and sepsis with Ceftriaxon].
Our expirience in the treatment of purulent meningitis and sepsis with third generation of cephalosporin--Cephtriaxon--are presented. In the last two years 13 of 44 patients suffering from purulent meningitis were treated with Cephtriaxon. They were all succesfuly cured without complications and recurrence. The time of CSF normalisation was from 8-17 days, depending on the aethyological agent of meningitis. Cephtriaxon is the drug of choice for E. coli and Hemophilus influence meningitis. We achiewed good results in the treatment ob sepsis, and ten of these cases are presented. Our Staphylococcus aureus showed good susceptibility to Cephtriaxon, which is the reason of the good therapeutical results. The analysis of antibacterial activity of Cephtriaxon in bacteria isolated from blood and CSF cultures, revealed that 80 per cent of isolated bacteria were highly susceptible.
Dulović
O
O
Pavlović
M
M
Nikolić
S
S
Vujosević
M
M
Canić
M
M
D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D002443:Ceftriaxone / Q000627:therapeutic use*; D006801:Humans; D016920:Meningitis, Bacterial / Q000188:drug therapy* / Q000382:microbiology; D018805:Sepsis / Q000188:drug therapy*
D000900:Anti-Bacterial Agents; D002443:Ceftriaxone