title: Potential roles for estrogen regulation of telomerase activity in aging.
abstract: Estrogen regulates tissue development, function, and aging by regulating expression of critical genes. Recent studies suggest that estrogen promotes cell proliferation by stimulating telomerase activity, an enzyme that plays a key role in extending cell life span. In some estrogen-responsive tissues, estrogen appears important in regulating telomerase activity in vivo. Further characterization will provide a greater understanding of the link between estrogen, telomerase, and aging.
authors.affiliation: Department of Immunology, Central and Eastern Clinical School, Monash University, Prahan, Victoria 3181, Australia.
authors.forename: Sharyn
authors.initials: S
authors.lastname: Bayne
authors.forename: Margaret E E
authors.initials: ME
authors.lastname: Jones
authors.forename: He
authors.initials: H
authors.lastname: Li
authors.forename: Jun-Ping
authors.initials: JP
authors.lastname: Liu
mesh_terms: D000375:Aging / Q000378:metabolism* / Q000502:physiology; D000818:Animals; D004967:Estrogens / Q000502:physiology*; D006801:Humans; D019098:Telomerase / Q000378:metabolism*
chemical_list: D004967:Estrogens; D019098:Telomerase