Wnt signaling: it gets more humorous with age.
In addition to its myriad of contributions in development, disease and regeneration, recent research implicates the Wnt/beta-catenin signaling cascade in yet another biological process - aging. The latest role of Wnt uncovers new complexities and opportunities for modulating the Wnt/beta-catenin pathway in regenerative medicine.
White
Bryan D
BD
Department of Pharmacology, Institute for Stem Cell and Regenerative Medicine, University of Washington School of Medicine, Seattle, Washington 98195, USA.
Nguyen
Nghi K
NK
Moon
Randall T
RT
D000375:Aging / Q000378:metabolism*; D000818:Animals; D051379:Mice; D044967:Serum / Q000737:chemistry; D015398:Signal Transduction; D013234:Stem Cells; D051153:Wnt Proteins / Q000378:metabolism*
D051153:Wnt Proteins