Impact of automatic orders to discontinue vancomycin therapy on vancomycin use in an antimicrobial stewardship program.
We examined the possible unintended consequences of a 72-hour automatic order to discontinue vancomycin therapy in an antimicrobial stewardship program (ASP). Of 120 patients, 11 had vancomycin therapy discontinued at 72 hours without a call to the ASP, and 7 experienced a treatment interruption of 6-36 hours. All discontinuation of therapy was considered appropriate, and the 7 treatment interruptions did not have clear clinical consequences. Only one-third of patients had ASP stickers that warned of impending discontinuation of vancomycin therapy placed appropriately in the medical record.
Connor
Denise M
DM
Division of Infectious Diseases, Department of Medicine, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, PA 19104-6021, USA.
Binkley
Shawn
S
Fishman
Neil O
NO
Gasink
Leanne B
LB
Linkin
Darren
D
Lautenbach
Ebbing
E
D000900:Anti-Bacterial Agents / Q000008:administration & dosage*; D001331:Automation; D019091:Critical Pathways; D004334:Drug Administration Schedule; D005572:Formularies, Hospital as Topic; D006785:Hospitals, University; D006801:Humans; D008485:Medical Audit; D008499:Medical Records / Q000706:statistics & numerical data; D014640:Vancomycin / Q000008:administration & dosage*
D000900:Anti-Bacterial Agents; D014640:Vancomycin