title: An immunofluorescence-histochemistry study of the Nogo receptor in the rat retina during postnatal development.
abstract: We investigated expression of the Nogo receptor (NgR) in the retina of rats between postnatal day 0 (PND 0) and adulthood (PND 63). Frozen sections of eyeball were prepared from each of six rats on PND 0, PND 3, PND 7, PND 14, PND 21, PND 35, PND 49, and PND 63. Immunofluorescence-histochemistry and laser-confocal microscopy were used to observe the expression of NgR protein. NgR is positive in the retina at all stages. It was distributed around ganglion cell nuclei and disposed linearly in the optic nerve. The NgR was expressed in rat retina at the time of birth and was present throughout postnatal development.
authors.affiliation: Department of Ophthalmology, Daping Hospital, Third Military Medical University, 10, Changjiang Zhilu, Daping, Chongqing, 400042, China. yinxiaolei971221@163.com
authors.forename: Xiaolei
authors.initials: X
authors.lastname: Yin
authors.forename: Chunlin
authors.initials: C
authors.lastname: Chen
authors.forename: Rongdi
authors.initials: R
authors.lastname: Yuan
authors.forename: Jian
authors.initials: J
authors.lastname: Ye
mesh_terms: D000375:Aging / Q000378:metabolism*; D000818:Animals; D000831:Animals, Newborn / Q000254:growth & development* / Q000378:metabolism*; D002467:Cell Nucleus / Q000378:metabolism; D005455:Fluorescent Antibody Technique; D058851:GPI-Linked Proteins; D006651:Histocytochemistry; D018613:Microscopy, Confocal; D009185:Myelin Proteins; D000070816:Nogo Receptor 1; D009900:Optic Nerve / Q000378:metabolism; D051381:Rats; D017207:Rats, Sprague-Dawley; D011956:Receptors, Cell Surface; D018000:Receptors, Peptide / Q000378:metabolism*; D012160:Retina / Q000378:metabolism*; D012165:Retinal Ganglion Cells / Q000378:metabolism; D014018:Tissue Distribution
chemical_list: D058851:GPI-Linked Proteins; D009185:Myelin Proteins; D000070816:Nogo Receptor 1; D011956:Receptors, Cell Surface; D018000:Receptors, Peptide; C486581:Rtn4r protein, rat