Lewis acid-catalyzed cascade reactions of arylmethylenecyclopropanes with 1,1,3-triarylprop-2-yn-1-ols or their methyl ethers.
Arylmethylenecyclopropanes 1 can react with 3-methoxy-1,3,3-triarylprop-1-yne 2 or 1,1,3-triarylprop-2-yn-1-ol 2-OH to give the corresponding functionalized methylenecyclobutene, cyclobutane, and cyclopropane derivatives in the presence of Lewis acid BF3.OEt2 under mild conditions. A plausible Meyer-Schuster rearrangement mechanism has been proposed.
Yao
Liang-Feng
LF
School of Chemistry & Molecular Engineering, East China University of Science and Technology, 130 Mei Long Lu, Shanghai 200237, China.
Shi
Min
M