Aging within the Stem Cell niche.
Decreased adult stem cell function is thought to play a primary role in organismal aging. Two recent papers in Cell Stem Cell demonstrate the importance of signaling from the stem cell niche in the aging of Drosophila germline stem cells.
Wallenfang
Matthew R
MR
Department of Biological Sciences, Barnard College, 3009 Broadway, New York, NY 10027, USA. Electronic address: mwallenf@barnard.edu.
D000818:Animals; D016922:Cellular Senescence; D004330:Drosophila / Q000166:cytology / Q000254:growth & development / Q000502:physiology*; D005260:Female; D005854:Germ Cells / Q000166:cytology / Q000502:physiology; D006801:Humans; D008297:Male; D015398:Signal Transduction; D013234:Stem Cells / Q000166:cytology / Q000502:physiology*