DNA sensing by field-effect transistors based on networks of carbon nanotubes.
We report on the sensing mechanism of electrical detection of deoxyribonucleic acid (DNA) hybridization for Au- and Cr-contacted field effect transistors based on single-walled carbon nanotube (SWCNT) networks. Barrier height extraction via low-temperature electrical measurement provides direct evidence for the notion that the energy level alignment between electrode and SWCNTs can be affected by DNA immobilization and hybridization. The study of location-selective capping using photoresist provides comprehensive evidence that the sensing of DNA is dominated by the change in metal-SWCNT junctions rather than the channel conductance.
Gui
Ee Ling
EL
School of Materials Science and Engineering, Nanyang Technological University 50, Nanyang Avenue, Singapore, 639798.
Li
Lain-Jong
LJ
Zhang
Keke
K
Xu
Yangping
Y
Dong
Xiaochen
X
Ho
Xinning
X
Lee
Pooi See
PS
Kasim
Johnson
J
Shen
Z X
ZX
Rogers
John A
JA
Mhaisalkar
S G
SG
D015374:Biosensing Techniques / Q000295:instrumentation / Q000379:methods*; D002857:Chromium / Q000737:chemistry; D015342:DNA Probes / Q000737:chemistry*; D004563:Electrochemistry; D004566:Electrodes; D006046:Gold / Q000737:chemistry; D017403:In Situ Hybridization / Q000295:instrumentation / Q000379:methods*; D008856:Microscopy, Fluorescence; D037742:Nanotubes, Carbon / Q000737:chemistry*; D013059:Spectrum Analysis, Raman; D014173:Transistors, Electronic
D015342:DNA Probes; D037742:Nanotubes, Carbon; D002857:Chromium; D006046:Gold