title: Liver flukes in dogs and treatment with praziquantel.
abstract: Opisthorchiid eggs were found in 6 out of 27 (22%) huskies while an ELISA detected antibodies against Opisthorchis felineus and Metorchis bilis in 24 (89%) and 25 (93%) sera taken from these dogs, respectively. All dogs showed an increased activity of glutamate dehydrogenase while aspartate aminotransferase was normal in all samples. Ten weeks after treatment with praziquantel no fluke eggs were found in the faeces from any animal and antibody titres dropped in all animals.
authors.affiliation: Institut für Parasitologie und Tropenveterinärmedizin, Freie Universität Berlin, Königsweg 67, 14163, Berlin, Germany. moniezia@zedat.fu-berlin.de
authors.forename: R K
authors.initials: RK
authors.lastname: Schuster
authors.forename: J
authors.initials: J
authors.lastname: Heidrich
authors.forename: A
authors.initials: A
authors.lastname: Pauly
authors.forename: K
authors.initials: K
authors.lastname: Nöckler
mesh_terms: D000410:Alanine Transaminase / Q000032:analysis; D000469:Alkaline Phosphatase / Q000032:analysis; D000818:Animals; D000871:Anthelmintics / Q000627:therapeutic use*; D000913:Antibodies, Protozoan / Q000097:blood; D000953:Antigens, Protozoan / Q000276:immunology; D001219:Aspartate Aminotransferases / Q000032:analysis; D004283:Dog Diseases / Q000188:drug therapy*; D004285:Dogs; D004305:Dose-Response Relationship, Drug; D005210:Fasciola hepatica / Q000187:drug effects* / Q000276:immunology; D005211:Fascioliasis / Q000188:drug therapy / Q000662:veterinary*; D005969:Glutamate Dehydrogenase / Q000032:analysis; D008099:Liver / Q000201:enzymology / Q000469:parasitology; D011223:Praziquantel / Q000627:therapeutic use*; D016896:Treatment Outcome
chemical_list: D000871:Anthelmintics; D000913:Antibodies, Protozoan; D000953:Antigens, Protozoan; D011223:Praziquantel; D005969:Glutamate Dehydrogenase; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase; D000469:Alkaline Phosphatase