[Studies on chemical constituents of rhizomes of Ligusticum chuanxiong].
OBJECTIVE
To study chemical constitutents of the rhizomes of Ligusticum chuanxiong.


METHODS
The rhizomes of L. chuanxiong were extracted with water to afford a water extract which was participated between H2O and EtOAc, n-BuOH, successively. The compounds were isolatedand purified by column chromatography from the EtOAc fraction, and identified based on spectral analyses.


RESULTS
Eleven compounds were isolated from the rhizomes of L. chuanxiong, and structures were characterized as (4S)-p-menth-1-ene4, 7-diol (1), aromadendrane-4alpha, 10beta-diol (2), aromadendrane-4beta, 10alpha-diol (3), aromadendrane-4beta, 10beta-diol (4), augustic acid (5), xiongterpene (6), pregnenolone (7), 3(R), 8(S), 9(Z)-falcarindiol (8), senkyunolide F (9), senkyunolide I (10), 4-hydroxyl-3-butylphthalide (11).


CONCLUSIONS
Compounds 1-5 were obtained from the rhizomes of L. chuanxiong for the first time.
Chang
Xin-liang
XL
State Key Labortatory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, China.
Ma
Yun-bao
YB
Zhang
Xue-mei
XM
Jiang
Zhi-yong
ZY
Chen
Ji-jun
JJ
D030004:Ligusticum / Q000737:chemistry*; D009828:Oleanolic Acid / Q000031:analogs & derivatives* / Q000737:chemistry / Q000302:isolation & purification; D010946:Plants, Medicinal / Q000737:chemistry*; D011284:Pregnenolone / Q000737:chemistry / Q000302:isolation & purification; D027343:Rhizome / Q000737:chemistry; D013729:Terpenes / Q000737:chemistry / Q000302:isolation & purification*
D013729:Terpenes; C525519:augustic acid; C525518:p-menth-1-ene-4,7-diol; C478708:xiongterpene; D009828:Oleanolic Acid; D011284:Pregnenolone