title: [Successfull extirpation of femoral pseudotumour in a patient with severe haemophilia A and an inhibitor to factor VIII].
abstract: The article deals with a successfull extirpation of femoral pseudotumour in a 53-year-old patient with severe haemophilia A (F VIII: C less than 1%) and an inhibitor to factor VIII. Such case is the first one reported in Yugoslavia. A combination of ultrasonography, computed axial tomography, angiography and Tc-99m labelled red blood cell scintigraphy was used for precise diagnosis of the pseudotumour. Preoperative preparation consisted of 50 units/kg of concentrate of F VIII (Hemate P) and 50 units/kg of activated prothrombine complex concentrate (FEIBA). A pseudotumour, 15 cm in diameter, was extirpated, as well as a few dauther cysts. F VIII concentrate was used for postoperative supportive therapy. On the 5-th postoperative day the patient prematurely rose from his bed and the "secondary bleeding" had to be treated with F VIII concentrate. The success of complex operations in haemophiliacs is possible only in big centres which can provide the best diagnostic procedures, trained surgeon teams, and modern and various supportive therapy.
authors.forename: D
authors.initials: D
authors.lastname: Marisavljević
authors.forename: M
authors.initials: M
authors.lastname: Glisić
authors.forename: I
authors.initials: I
authors.lastname: Elezović
authors.forename: A
authors.initials: A
authors.lastname: Popović
authors.forename: Z
authors.initials: Z
authors.lastname: Rolović
mesh_terms: D005169:Factor VIII / Q000276:immunology / Q000627:therapeutic use*; D005269:Femur / Q000601:surgery*; D006406:Hematoma / Q000209:etiology / Q000601:surgery*; D006467:Hemophilia A / Q000097:blood / Q000150:complications*; D006801:Humans; D008297:Male; D008875:Middle Aged; D019990:Perioperative Care
chemical_list: D005169:Factor VIII