title: [Transport of ergot alkaloids and quinocitrinins in the producing fungus Penicillium citrinum].
abstract: The decrease in the concentration of alkaloids in the culture liquid of Penicillium citrinum grown to the early stationary phase was found to be due to the uptake of quinocitrinins and ergot alkaloids by fungal cells. The ability of the fungal mycelium to absorb autogenous quinocitrinins does not depend on the mycelium age, whereas its ability to absorb ergot alkaloids is higher in the young than in the 12-day-old mycelium. The uptake of exogenously added ergot alkaloids by the fungal mycelium is accompanied by excretion of intracellular quinocitrinins. The addition of quinocitrinins to the medium was found to exert different effects in different growth stages. Namely, the uptake of exogenously added quinocitrinins by the actively growing young mycelium inhibits the excretion of ergot alkaloids, but the excretion of ergot alkaloids by the 12- day-old mycelium occurs throughout the cultivation period. The excretion of both ergot alkaloids and quinocitrinins does not require energy.
authors.forename: V P
authors.initials: VP
authors.lastname: Zhelifonova
authors.forename: A G
authors.initials: AG
authors.lastname: Kozlovskiĭ
mesh_terms: D000470:Alkaloids / Q000378:metabolism*; D001693:Biological Transport, Active; D004876:Ergot Alkaloids / Q000378:metabolism; D010407:Penicillium / Q000378:metabolism*; D011804:Quinolines / Q000378:metabolism*
chemical_list: D000470:Alkaloids; D004876:Ergot Alkaloids; D011804:Quinolines