title: [Hydroxy(tosyloxy)iodo]benzene mediated alpha-azidation of ketones.
abstract: Reaction of various ketones with [hydroxy(tosyloxy)iodo]benzene (HTIB) followed by treatment of the alpha-tosyloxy ketones thus generated in situ with NaN3 offers a one-pot procedure for the synthesis of alpha-azido ketones. The HTIB used in this conversion may also be generated in situ by using iodosobenzene in combination with p-toluene-sulphonic acid.
authors.affiliation: Department of Chemistry, Kurukshetra University, Kurukshetra, Haryana, India. dromprakash50@rediffmail.com
authors.forename: Om
authors.initials: O
authors.lastname: Prakash
authors.forename: Kamaljeet
authors.initials: K
authors.lastname: Pannu
authors.forename: Richa
authors.initials: R
authors.lastname: Prakash
authors.forename: Anita
authors.initials: A
authors.lastname: Batra
mesh_terms: D001386:Azides / Q000737:chemistry*; D001557:Benzenesulfonates / Q000737:chemistry; D007462:Iodobenzenes / Q000737:chemistry*; D007659:Ketones / Q000737:chemistry*
chemical_list: D001386:Azides; D001557:Benzenesulfonates; D007462:Iodobenzenes; D007659:Ketones; C029501:4-toluenesulfonic acid; C037276:iodosobenzene