title: Chromium hexacyanoferrate modified biosensor based on PQQ-dependent glucose dehydrogenase.
abstract: A Pyrroloquinoline quinone (PQQ)-dependent glucose dehydrogenase based platinum electrode was developed to detect glucose. Chromium hexacyanoferrate was modified onto this electrode to serve as an electron transfer mediator between PQQ and the platinum electrode. This biosensor showed the optimal response of glucose measurements at pH 7 and an operation potential of +0.4 V (vs. Ag/AgCl). More importantly the lifespan of the biosensor has been last for 47 days without significant enzyme activity degradation.
authors.affiliation: Biomedical Engineering Department, Chung-Yuan Christian University, Chung-Li 32023, Taiwan, ROC. g9402502@cycu.edu.tw
authors.forename: Ta-Feng
authors.initials: TF
authors.lastname: Tseng
authors.forename: Yang-Li
authors.initials: YL
authors.lastname: Yang
authors.forename: Shyh-Liang
authors.initials: SL
authors.lastname: Lou
mesh_terms: D015374:Biosensing Techniques; D002857:Chromium / Q000737:chemistry*; D004579:Electron Transport; D005295:Ferrocyanides / Q000737:chemistry*; D005947:Glucose / Q000032:analysis*; D005948:Glucose Dehydrogenases / Q000737:chemistry*; D045542:PQQ Cofactor / Q000737:chemistry*
chemical_list: D005295:Ferrocyanides; C116383:ferrocyn; D002857:Chromium; D045542:PQQ Cofactor; D005948:Glucose Dehydrogenases; D005947:Glucose