title: Retrospective comparison of retroperitoneoscopic versus open adrenalectomy for pheochromocytoma.
abstract: OBJECTIVE
  We compared the clinical outcomes of retroperitoneoscopic and open adrenalectomy for pheochromocytoma.
  
  
  METHODS
  Clinical data on 56 patients who underwent retroperitoneoscopic lateral adrenalectomy were retrospectively compared with those on 50 who underwent open adrenalectomy for pheochromocytoma, including patient demographic data, perioperative indexes and clinical outcomes.
  
  
  RESULTS
  Demographic data on patients were similar in the 2 groups. In the retroperitoneoscopic group such perioperative indexes were significantly different from those of the open group (each p <0.05), including operative time (mean +/- SD 52 +/- 22 vs 120 +/- 42 minutes), estimated blood loss (74 +/- 34 vs 187 +/- 64 ml), resumption of oral intake (1 vs 2 days), postoperative hospital stay (5.2 +/- 1.7 vs 8.3 +/- 1.8 days), incidence of intraoperative hypertension (17.0% or 9 of 53 patients vs 36.0% or 18 of 50) and number of patients requiring blood transfusion(1.8% or 1 of 53 vs 16.0% or 8 of 50). The incidence of systemic inflammatory response syndrome was much less in the retroperitoneoscopic group (20.8% or 11 of 53 patients vs 42.0% or 21 of 50, p <0.05). However, the duration of systemic inflammatory response syndrome and postoperative complications were similar in the 2 groups (p >0.05). Blood pressure returned to normal 3 months after the operation in 81% of the patients in the retroperitoneoscopic group and in 84% in the open group. During the followup of 5 to 36 months no tumor recurrence and/or metastasis developed.
  
  
  CONCLUSIONS
  Compared with open surgery retroperitoneoscopic lateral adrenalectomy for pheochromocytoma is a safe, minimally invasive and effective procedure.
authors.affiliation: Department of Urology, First Affiliated Hospital of Xinjiang Medical University, Urumqi, People's Republic of China.
authors.forename: Bin
authors.initials: B
authors.lastname: Lang
authors.forename: Bin
authors.initials: B
authors.lastname: Fu
authors.forename: Jin-Zhi
authors.initials: JZ
authors.lastname: OuYang
authors.forename: Bao-Jun
authors.initials: BJ
authors.lastname: Wang
authors.forename: Guo-Xi
authors.initials: GX
authors.lastname: Zhang
authors.forename: Kai
authors.initials: K
authors.lastname: Xu
authors.forename: Jun
authors.initials: J
authors.lastname: Zhang
authors.forename: Chao
authors.initials: C
authors.lastname: Wang
authors.forename: Tao-Ping
authors.initials: TP
authors.lastname: Shi
authors.forename: Hui-Xia
authors.initials: HX
authors.lastname: Zhou
authors.forename: Xin
authors.initials: X
authors.lastname: Ma
authors.forename: Xu
authors.initials: X
authors.lastname: Zhang
mesh_terms: D000310:Adrenal Gland Neoplasms / Q000601:surgery*; D000315:Adrenalectomy / Q000379:methods*; D000328:Adult; D005260:Female; D006801:Humans; D010535:Laparoscopy; D008297:Male; D010673:Pheochromocytoma / Q000601:surgery*; D012189:Retrospective Studies