title: Radial optic neurotomy using nasal and temporal approach incisions: histopathologic study in human cadaver eyes.
abstract: OBJECTIVE
  To examine the structural effect of radial optic neurotomy (RON) using nasal and temporal approach incisions on the nasal side of the optic nerve (ON) using dominant and nondominant hands in human cadaver eyes.
  
  
  METHODS
  Transvitreal RON was performed in 9 eyes with a microvitreoretinal blade by a right-handed surgeon. A nasal approach was used in 4 left eyes (using the right hand) and in 2 right eyes (using the left hand), and a temporal approach was used in 3 right eyes (using the right hand). Histologic sections were examined for depth of nerve penetration and for effect on critical structures.
  
  
  RESULTS
  The scleral canal was fully incised in all cases. The mean depth of nerve penetration was 555 micro25 microing the nasal approach and 246.7 microing the temporal approach) (P =.12). The globe was not ruptured in any eye. In a single right eye approached temporally using the right hand, the adventitial sheath of the central retinal artery was lacerated.
  
  
  CONCLUSIONS
  RON in human cadaver eyes results in lysis of the scleral canal at the ON head. Greater depth and improved safety of incision can be achieved by always approaching the incision from the nasal side of the ON using the dominant or nondominant hand.
authors.affiliation: Department of Ophthalmology and Visual Sciences, University of Wisconsin, 2870 University Ave, Ste 206, Madison, WI 53705, USA. mmaltaweel@wisc.edu
authors.forename: Michael M
authors.initials: MM
authors.lastname: Altaweel
authors.forename: Lars
authors.initials: L
authors.lastname: Freisberg
authors.forename: Nikhil
authors.initials: N
authors.lastname: Pal
authors.forename: Joel
authors.initials: J
authors.lastname: Gleiser
authors.forename: Edwin H
authors.initials: EH
authors.lastname: Ryan
authors.forename: Daniel
authors.initials: D
authors.lastname: Dawson
authors.forename: Daniel
authors.initials: D
authors.lastname: Albert
mesh_terms: D002102:Cadaver; D019299:Decompression, Surgical / Q000379:methods*; D006801:Humans; D008954:Models, Biological; D013508:Ophthalmologic Surgical Procedures; D009900:Optic Nerve / Q000473:pathology* / Q000601:surgery*; D009901:Optic Nerve Diseases / Q000601:surgery; D012590:Sclera / Q000473:pathology / Q000601:surgery