title: Electrocardiographic signs of remote myocardial infarction.
abstract: Twelve-lead electrocardiogram is an integral part of the evaluation of an acute and a remote myocardial infarction (MI). Electrocardiographic signs of an acute ST-elevation MI are more precise than those of an acute non-ST-elevation MI. Recognition of a remote MI is more difficult because once the repolarization abnormalities (ST-segment and T-wave changes) stabilize after an acute MI resolves, then the Q wave remains as the only universally recognized sign of MI. In addition, there is no specific sign of a non-Q-wave MI or a non-ST-elevation MI, or in fact of an ST-elevation MI that did not result in Q waves. The fragmented QRS (fQRS) is another recently described sign of a remote MI. It is defined by the presence of an additional R wave (R') or notching in the nadir of the S wave, or the presence of >1 R' (fragmentation) in 2 contiguous leads corresponding to a major coronary artery territory. The specificity of fQRS is inferior to that of a Q wave for an MI scar (89% vs 99%). However, fQRS has a superior sensitivity and a negative predictive value compared with a Q wave. In addition, there is an incremental gain in the sensitivity up to 91.4% when these 2 signs (fQRS and Q wave) are combined. The repolarization abnormalities of MI may also persist indefinitely as a sign of a remote MI in few patients. These abnormalities include persistent ST elevation, ST depression, nonspecific ST-T wave changes, and T-wave inversion.
authors.affiliation: Krannert Institute of Cardiology, Indiana University School of Medicine, Indianapolis, IN, USA.
authors.forename: Mark A
authors.initials: MA
authors.lastname: Michael
authors.forename: Hicham
authors.initials: H
authors.lastname: El Masry
authors.forename: Bilal R
authors.initials: BR
authors.lastname: Khan
authors.forename: Mithilesh K
authors.initials: MK
authors.lastname: Das
mesh_terms: D000200:Action Potentials; D004562:Electrocardiography; D006329:Heart Conduction System / Q000503:physiopathology*; D006801:Humans; D009203:Myocardial Infarction / Q000175:diagnosis* / Q000209:etiology / Q000503:physiopathology; D017202:Myocardial Ischemia / Q000150:complications* / Q000503:physiopathology; D011237:Predictive Value of Tests; D011379:Prognosis; D012680:Sensitivity and Specificity; D012720:Severity of Illness Index