title: CD4+/CD56+ hematodermic neoplasm: blastic NK cell lymphoma in a 6-year-old child: report of a case and review of literature.
abstract: A 6-year-old girl presented with disseminated polymorphous skin lesions of several months' duration, joint pains, recurrent fever, anemia, and inguinal adenopathy. Subsequent evaluation of skin, lymph node, and bone marrow morphology showed infiltration of atypical lymphocytic cells. Immunohistochemical and flow cytometric analysis showed findings consistent with the rare but highly malignant blastic Natural killer cell lymphoma/leukemia also termed CD4/CD56 hematodermic neoplasm.
authors.affiliation: Department of Pediatrics, Section of Hematology-Oncology, University of the Philippines-Philippine General Hospital, Manila, Philippines.
authors.forename: Ann Veronique C
authors.initials: AV
authors.lastname: Eguaras
authors.forename: Raymundo W
authors.initials: RW
authors.lastname: Lo
authors.forename: Januario D
authors.initials: JD
authors.lastname: Veloso
authors.forename: Vivian Grace
authors.initials: VG
authors.lastname: Tan
authors.forename: Ma Luisa D
authors.initials: ML
authors.lastname: Enriquez
authors.forename: Ma Luz U
authors.initials: ML
authors.lastname: Del Rosario
mesh_terms: D015704:CD4 Antigens / Q000032:analysis; D019002:CD56 Antigen / Q000032:analysis; D002648:Child; D005260:Female; D006801:Humans; D007694:Killer Cells, Natural / Q000473:pathology; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000175:diagnosis* / Q000473:pathology; D012878:Skin Neoplasms / Q000175:diagnosis* / Q000473:pathology
chemical_list: D015704:CD4 Antigens; D019002:CD56 Antigen