title: [Seroepidemiology studies on population immune background to viral hepatitis B].
abstract: METHODS
  The studies have been carried out in 855 males and females aged over 20 years belonging to the general population and health care profession included in the European Sero-Epidemiology Network (ESEN) Programme aimed at assessing the population immune background against hepatitis B virus. The serological markers, represented by HBsAg, antibodies to HBsAg (anti-HBsAg) and HBcAg (anti-HBcAg) were investigated by the methods widely used in seroepidemiology studies. The patients were divided into 4 subgroups.
  
  
  RESULTS
  In the blood serum of a subgroup of 220 individuals, HBsAg was found in 33.2%, anti-HBs in 41.3%, and anti-HBc in 25.4%. In another subgroup of 219 individuals, significantly increased levels of the anti-HBs were recorded in 50.2%. In the subgroup of 168 individuals, IgG anti-HBc were present in 84.6% of those aged over 40 years who had acute HBV infection. In the subgroup of 248 healthcare professionals the prevalence of anti-HBs carriers was 50-80%, result of vaccine-prevention.
authors.affiliation: Compartimentul de Epidemiologie, Autoritatea de Sănătate Publică Iaşi.
authors.forename: Elena
authors.initials: E
authors.lastname: Duca
authors.forename: Angela
authors.initials: A
authors.lastname: Romaniuc
authors.forename: Mihaela
authors.initials: M
authors.lastname: Trifan
authors.forename: D
authors.initials: D
authors.lastname: Butur
authors.forename: A
authors.initials: A
authors.lastname: Ivan
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D015415:Biomarkers / Q000097:blood; D002648:Child; D002675:Child, Preschool; D005260:Female; D006509:Hepatitis B / Q000453:epidemiology / Q000276:immunology*; D006510:Hepatitis B Antibodies / Q000097:blood; D006512:Hepatitis B Core Antigens / Q000097:blood*; D006514:Hepatitis B Surface Antigens / Q000097:blood*; D006515:Hepatitis B virus / Q000276:immunology; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012383:Romania / Q000453:epidemiology; D016036:Seroepidemiologic Studies
chemical_list: D015415:Biomarkers; D006510:Hepatitis B Antibodies; D006512:Hepatitis B Core Antigens; D006514:Hepatitis B Surface Antigens