title: ProtozoaDB: dynamic visualization and exploration of protozoan genomes.
abstract: ProtozoaDB (http://www.biowebdb.org/protozoadb) is being developed to initially host both genomics and post-genomics data from Plasmodium falciparum, Entamoeba histolytica, Trypanosoma brucei, T. cruzi and Leishmania major, but will hopefully host other protozoan species as more genomes are sequenced. It is based on the Genomics Unified Schema and offers a modern Web-based interface for user-friendly data visualization and exploration. This database is not intended to duplicate other similar efforts such as GeneDB, PlasmoDB, TcruziDB or even TDRtargets, but to be complementary by providing further analyses with emphasis on distant similarities (HMM-based) and phylogeny-based annotations including orthology analysis. ProtozoaDB will be progressively linked to the above-mentioned databases, focusing in performing a multi-source dynamic combination of information through advanced interoperable Web tools such as Web services. Also, to provide Web services will allow third-party software to retrieve and use data from ProtozoaDB in automated pipelines (workflows) or other interoperable Web technologies, promoting better information reuse and integration. We also expect ProtozoaDB to catalyze the development of local and regional bioinformatics capabilities (research and training), and therefore promote/enhance scientific advancement in developing countries.
authors.affiliation: Oswaldo Cruz Institute, FIOCRUZ, CCB, Federal University of Santa Catarina (UFSC), ACBS/UNOESC/SC, COPPE, Federal University of Rio de Janeiro, Brazil. davila@fiocruz.br
authors.forename: Alberto M R
authors.initials: AM
authors.lastname: Dávila
authors.forename: Pablo N
authors.initials: PN
authors.lastname: Mendes
authors.forename: Glauber
authors.initials: G
authors.lastname: Wagner
authors.forename: Diogo A
authors.initials: DA
authors.lastname: Tschoeke
authors.forename: Rafael R C
authors.initials: RR
authors.lastname: Cuadrat
authors.forename: Felipe
authors.initials: F
authors.lastname: Liberman
authors.forename: Luciana
authors.initials: L
authors.lastname: Matos
authors.forename: Thiago
authors.initials: T
authors.lastname: Satake
authors.forename: Kary A C S
authors.initials: KA
authors.lastname: Ocaña
authors.forename: Omar
authors.initials: O
authors.lastname: Triana
authors.forename: Sérgio M S
authors.initials: SM
authors.lastname: Cruz
authors.forename: Henrique C L
authors.initials: HC
authors.lastname: Jucá
authors.forename: Juliano C
authors.initials: JC
authors.lastname: Cury
authors.forename: Fabricio N
authors.initials: FN
authors.lastname: Silva
authors.forename: Guilherme A
authors.initials: GA
authors.lastname: Geronimo
authors.forename: Margarita
authors.initials: M
authors.lastname: Ruiz
authors.forename: Eduardo
authors.initials: E
authors.lastname: Ruback
authors.forename: Floriano P
authors.initials: FP
authors.lastname: Silva
authors.forename: Christian M
authors.initials: CM
authors.lastname: Probst
authors.forename: Edmundo C
authors.initials: EC
authors.lastname: Grisard
authors.forename: Marco A
authors.initials: MA
authors.lastname: Krieger
authors.forename: Samuel
authors.initials: S
authors.lastname: Goldenberg
authors.forename: Maria C R
authors.initials: MC
authors.lastname: Cavalcanti
authors.forename: Milton O
authors.initials: MO
authors.lastname: Moraes
authors.forename: Maria L M
authors.initials: ML
authors.lastname: Campos
authors.forename: Marta
authors.initials: M
authors.lastname: Mattoso
mesh_terms: D000818:Animals; D003196:Computer Graphics; D030541:Databases, Genetic; D004748:Entamoeba histolytica / Q000235:genetics; D018503:Genome, Protozoan; D023281:Genomics; D020407:Internet; D018320:Leishmania major / Q000235:genetics; D010963:Plasmodium falciparum / Q000235:genetics; D015800:Protozoan Proteins / Q000737:chemistry; D012984:Software; D014346:Trypanosoma brucei brucei / Q000235:genetics; D014349:Trypanosoma cruzi / Q000235:genetics; D014584:User-Computer Interface
chemical_list: D015800:Protozoan Proteins