title: Sulfated zirconia-catalyzed synthesis of 3,4-dihydropyrimidin-2(1H)-ones (DHPMs) under solventless conditions: competitive multicomponent Biginelli vs. Hantzsch reactions.
abstract: The catalytic ability of ZrO(2)/SO(4)(2-) to promote solventless three-component condensation reactions of a diversity of aromatic aldehydes, urea or thoiurea and ethyl acetoacetate was studied. Products resulting from Hantzsch and/or Biginelli multi-component reactions are obtained in the presence of solid acid catalysts using the same reactants but different temperature conditions. The sulfated zirconia catalyst can be recovered and recycled in subsequent reactions with a gradual decrease of activity.
authors.affiliation: Departamento de Ciencias Básicas, UAM, Av. San Pablo No 180. C. P. 02200, México. dab@correo.azc.uam.mx
authors.forename: Deyanira
authors.initials: D
authors.lastname: Angeles-Beltrán
authors.forename: Leticia
authors.initials: L
authors.lastname: Lomas-Romero
authors.forename: Victor H
authors.initials: VH
authors.lastname: Lara-Corona
authors.forename: Eduardo
authors.initials: E
authors.lastname: González-Zamora
authors.forename: Guillermo
authors.initials: G
authors.lastname: Negrón-Silva
mesh_terms: D002384:Catalysis; D011744:Pyrimidinones / Q000138:chemical synthesis* / Q000737:chemistry; D012997:Solvents; D013431:Sulfates / Q000138:chemical synthesis / Q000737:chemistry; D015040:Zirconium / Q000737:chemistry
chemical_list: D011744:Pyrimidinones; D012997:Solvents; D013431:Sulfates; D015040:Zirconium; C028541:zirconium oxide