title: Successful treatment of severe gastrointestinal involvement in adult-onset Henoch-Schönlein purpura.
abstract: Henoch-Schönlein purpura is a small vessel vasculitis which is uncommon in adults. The presentations of adult-onset disease are different from those seen in childhood. The commonly-recognised serious gastrointestinal complications of childhood are less well-documented in adults. We report three cases of adult-onset Henoch-Schönlein purpura with severe gastrointestinal involvement. All were men, aged 22, 35 and 42 years, respectively. Two of these patients had evidence of mesenteric ischaemia on computed tomography of the abdomen. All three patients were successfully treated with steroids.
authors.affiliation: Department of Internal Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India. amansharma74@yahoo.com
authors.forename: A
authors.initials: A
authors.lastname: Sharma
authors.forename: A
authors.initials: A
authors.lastname: Wanchu
authors.forename: N
authors.initials: N
authors.lastname: Kalra
authors.forename: S
authors.initials: S
authors.lastname: Singh
authors.forename: P
authors.initials: P
authors.lastname: Bambery
mesh_terms: D015746:Abdominal Pain / Q000209:etiology*; D000284:Administration, Oral; D000328:Adult; D001706:Biopsy; D002196:Capillaries / Q000473:pathology; D003176:Complement C3 / Q000378:metabolism; D003248:Constipation / Q000209:etiology*; D006471:Gastrointestinal Hemorrhage / Q000209:etiology*; D006801:Humans; D011695:IgA Vasculitis / Q000175:diagnosis* / Q000188:drug therapy; D007085:Ilium / Q000098:blood supply; D007070:Immunoglobulin A / Q000378:metabolism; D007262:Infusions, Intravenous; D007421:Intestine, Small / Q000098:blood supply*; D007511:Ischemia / Q000175:diagnosis* / Q000188:drug therapy; D008297:Male; D008641:Mesenteric Vascular Occlusion / Q000175:diagnosis* / Q000188:drug therapy; D008775:Methylprednisolone / Q000008:administration & dosage; D009780:Occult Blood; D011241:Prednisone / Q000008:administration & dosage; D012867:Skin / Q000098:blood supply; D014057:Tomography, X-Ray Computed; D018366:Vasculitis, Leukocytoclastic, Cutaneous / Q000175:diagnosis / Q000188:drug therapy; D014839:Vomiting / Q000209:etiology*
chemical_list: D003176:Complement C3; D007070:Immunoglobulin A; D011241:Prednisone; D008775:Methylprednisolone