title: Investigating new BioMEMS techniques for early detection of osteoporosis.
abstract: Osteoporosis is a bone disease which requires early detection. The biomarkers provide a promising challenge of clinical proteomics for early disease detection. Different techniques like BMD testing, optical and electrochemical testing have been studied comparatively. New peaks have been identified in UV-visible spectroscopy at 420nm and high sensitivity is achieved by electrochemical technique with ng/ml to pico/ml level detection of bonemarkers. An electrochemical technique is found to be the best suitable for developing a new bioMEMS chip.
authors.affiliation: MEMS/Nano Technology Center, Pusan National University, Busan, South Korea. kstechinfo@yahoo.com
authors.forename: Kanika
authors.initials: K
authors.lastname: Singh
authors.forename: Kyung Chun
authors.initials: KC
authors.lastname: Kim
mesh_terms: D015415:Biomarkers / Q000378:metabolism*; D001847:Bone Diseases / Q000175:diagnosis / Q000628:therapy; D001842:Bone and Bones / Q000378:metabolism; D042241:Early Diagnosis; D004563:Electrochemistry / Q000379:methods*; D004867:Equipment Design; D006801:Humans; D010024:Osteoporosis / Q000175:diagnosis* / Q000473:pathology*; D040901:Proteomics / Q000295:instrumentation* / Q000379:methods*; D015203:Reproducibility of Results; D013056:Spectrophotometry, Ultraviolet / Q000295:instrumentation* / Q000379:methods; D013997:Time Factors
chemical_list: D015415:Biomarkers