New reference values for forced spirometry in white adults in Brazil.
OBJECTIVE
To describe spirometric reference equations for healthy Brazilian adults who have never smoked and to compare the predicted values with those derived in 1992.


METHODS
Reference equations for spirometry were derived in 270 men and 373 women living in eight cities in Brazil. Ages ranged from 20 to 85 years in women and from 26 to 86 years in men. Spirometry examinations followed the recommendations of the Brazilian Thoracic Society. Lower limits were derived by the analysis of the fifth percentiles of the residuals.


RESULTS
Forced vital capacity (FVC), forced expiratory volume in one second (FEV1), FEV1/FVC and FEV1/forced expiratory volume in six seconds (FEV6) were best fitted by linear regression. Flows were best fitted using log equations. For both genders, greater height resulted in lower values for FEV1/FVC, FEV1/FEV6 and flow/FVC ratios. The reference values for FEV1 and FVC in the present study were higher than those derived for Brazilian adults in 1992.


CONCLUSIONS
New predicted values for forced spirometry were obtained in a sample of white Brazilians. The values are greater than those obtained in 1992, probably due to technical factors.
Pereira
Carlos Alberto de Castro
CA
Service of Pulmonology Department, Hospital do Servidor Público Estadual, HSPE, São Paulo, SP, Brazil. pereirac@uol.com.br
Sato
Taeko
T
Rodrigues
Sílvia Carla
SC
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000886:Anthropometry; D001938:Brazil; D005260:Female; D005540:Forced Expiratory Flow Rates / Q000502:physiology; D005541:Forced Expiratory Volume / Q000502:physiology; D006801:Humans; D016014:Linear Models; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D012016:Reference Values; D012129:Respiratory Function Tests; D013147:Spirometry; D014797:Vital Capacity / Q000502:physiology*; D044465:White People