A simulation-based study of reconstruction in time-resolved fluorescence diffuse optical tomography in cylindrical geometry.
The present paper is devoted to fluorescence diffuse optical tomography by using time resolved signals for the reconstruction of the 3D biodistribution of fluorescent probes embedded in biological tissues. The focus is made on the reconstruction of a methodology for an efficient exploitation of the time resolved data. The study is restricted to the examination of the three first moments of signals acquired in cylindrical geometry. The interest of temporal information upon CW information has been shown especially when only a limited number of views is available.
Ducros
Nicolas
N
Micro Technologies for Biology and Healthcare Division, CEA-LETI MINATEC, 17 rue des Martyrs, 38054 Grenoble, France. nicolas.ducros@cea.fr
Da Silva
Anabela
A
Dinten
Jean-Marc
JM
Peyrin
Françoise
F
D003198:Computer Simulation; D019047:Phantoms, Imaging; D013050:Spectrometry, Fluorescence / Q000379:methods; D041622:Tomography, Optical / Q000379:methods*