title: Ionic liquids as designer solvents for nucleophilic aromatic substitutions.
abstract: Ionic liquids were designed to optimize the nucleophilic aromatic substitution reaction of an activated aniline with an activated arylhalide. The design was achieved by selecting the anions on the basis of calculations of the gas-phase basicity of their conjugate acids.
authors.affiliation: GE Healthcare Bio-Sciences, The Grove Centre, White Lion Road Amersham, HP7 9LL, UK.
authors.forename: Ian
authors.initials: I
authors.lastname: Newington
authors.forename: Juan M
authors.initials: JM
authors.lastname: Perez-Arlandis
authors.forename: Tom
authors.initials: T
authors.lastname: Welton
mesh_terms: D005464:Fluorobenzenes / Q000737:chemistry; D052578:Ionic Liquids / Q000737:chemistry*; D015394:Molecular Structure; D012997:Solvents / Q000737:chemistry*
chemical_list: D005464:Fluorobenzenes; D052578:Ionic Liquids; D012997:Solvents