title: Is burnout related to allostatic load?
abstract: BACKGROUND
  Burnout has a negative impact on physical health, but the mechanisms underlying this relation remain unclear. To elucidate these mechanisms, possible mediating physiological systems or risk factors for adverse health in burned-out employees should be investigated.
  
  
  OBJECTIVE
  The aim of the present study among 290 Dutch managers was to explore whether allostatic load mediates the relationship between burnout and physical health.
  
  
  METHODS
  Burned-out managers, as identified with the Maslach Burnout Inventory General Survey (MBI-GS), were compared with a healthy control group with regard to their allostatic load. The allostatic load index included eight parameters: Body-mass index (BMI), systolic and diastolic blood pressure (SBP and DBP), C-reactive protein (CRP), high-density lipoprotein (HDL), cholesterol, glycosylated hemoglobin (HbA1C) and glucose.
  
  
  RESULTS
  Contrary to expectations, burned-out managers did not differ from healthy managers with regard to their scores on the allostatic load index. An additional analysis, using groups of managers in the extreme deciles of exhaustion (the core symptom of burnout), did also not reveal differences in allostatic load.
  
  
  CONCLUSIONS
  Burnout seems not to be associated with this proxy measure of allostatic load. The mediating physiological mechanisms between burnout and objective physical health remain to be elucidated.
authors.affiliation: Department of Psychology, Utrecht University, The Netherlands. s.langelaan@fss.uu.nl
authors.forename: Saar
authors.initials: S
authors.lastname: Langelaan
authors.forename: Arnold B
authors.initials: AB
authors.lastname: Bakker
authors.forename: Wilmar B
authors.initials: WB
authors.lastname: Schaufeli
authors.forename: Willem
authors.initials: W
authors.lastname: van Rhenen
authors.forename: Lorenz J P
authors.initials: LJ
authors.lastname: van Doornen
mesh_terms: D000222:Adaptation, Physiological; D000288:Administrative Personnel / Q000523:psychology*; D000328:Adult; D000704:Analysis of Variance; D001794:Blood Pressure; D015992:Body Mass Index; D002055:Burnout, Professional / Q000097:blood / Q000150:complications / Q000523:psychology*; D002097:C-Reactive Protein / Q000032:analysis; D016022:Case-Control Studies; D002784:Cholesterol / Q000097:blood; D005221:Fatigue / Q000503:physiopathology / Q000523:psychology*; D006801:Humans; D008875:Middle Aged; D009784:Occupational Diseases / Q000097:blood / Q000150:complications / Q000523:psychology; D012016:Reference Values; D012720:Severity of Illness Index; D013315:Stress, Psychological / Q000097:blood / Q000150:complications / Q000523:psychology*; D016526:Workload / Q000523:psychology*
chemical_list: D002097:C-Reactive Protein; D002784:Cholesterol