title: DTI-based virtual reality system for neurosurgery.
abstract: The relationship between tumor mass and peritumoral structures including peritumoral edema is important for planning surgical trajectory and crucial for diagnosis, tumor excision, and post-surgical outcome. The recent development of diffusion tensor MRI has shown its feasibility in grading tumor, monitoring therapeutic effects, and post-surgery outcome. To visualize the tumor mass and the peritumoral structure, a 3D virtual reality environment was developed. Neural tractography and peritumoral anatomy were integrated in this interaction VR system. Using a 3D controller, suitable surgical trajectory can be defined by manipulating the tumor mass, peritumoral microstructure, and brain tissues before neurosurgery. Post-surgery evaluation showed that this system was useful to design pre-surgical plan and optimize therapeutic outcome.
authors.affiliation: Institute of Biomedical Engineering, Chung-Yuan Christian University, Department of BME, CYCU, 200, Chung Pei Rd., Chung Li, Taiwan 32023. lgjbear@bclab.ym.edu.tw
authors.forename: Chun-Yi
authors.initials: CY
authors.lastname: Lo
authors.forename: Yi-Ping
authors.initials: YP
authors.lastname: Chao
authors.forename: Kun-Hsien
authors.initials: KH
authors.lastname: Chou
authors.forename: Wan-Yuo
authors.initials: WY
authors.lastname: Guo
authors.forename: Jenn-Lung
authors.initials: JL
authors.lastname: Su
authors.forename: Ching-Po
authors.initials: CP
authors.lastname: Lin
mesh_terms: D003196:Computer Graphics; D038524:Diffusion Magnetic Resonance Imaging / Q000295:instrumentation* / Q000379:methods; D004867:Equipment Design; D019544:Equipment Failure Analysis; D007090:Image Interpretation, Computer-Assisted / Q000295:instrumentation* / Q000379:methods; D021621:Imaging, Three-Dimensional / Q000295:instrumentation* / Q000379:methods; D019635:Neurosurgical Procedures / Q000295:instrumentation* / Q000379:methods; D025321:Surgery, Computer-Assisted / Q000295:instrumentation* / Q000379:methods; D014584:User-Computer Interface