VAPOL phosphoric acid catalysis: the highly enantioselective addition of imides to imines.
The first highly enantioselective catalytic method for the preparation of chiral aminals via the addition of imide nucleophiles to imines is reported.
Liang
Yuxue
Y
Department of Chemistry, University of South Florida, 4202 E. Fowler Ave., Tampa, FL 33620, USA.
Rowland
Emily B
EB
Rowland
Gerald B
GB
Perman
Jason A
JA
Antilla
Jon C
JC
D002384:Catalysis; D007094:Imides / Q000737:chemistry*; D007097:Imines / Q000737:chemistry*; D008958:Models, Molecular; D010616:Phenanthrenes / Q000737:chemistry*; D010756:Phosphoric Acids / Q000737:chemistry*; D010797:Phthalimides / Q000737:chemistry; D013237:Stereoisomerism
D007094:Imides; D007097:Imines; D010616:Phenanthrenes; D010756:Phosphoric Acids; D010797:Phthalimides; C510253:VAPOL ligand