Symptom and structure modifying properties of chondroitin sulfate in osteoarthritis.
Chondroitin sulfate (CS) is a complex carbohydrate polymer with variable sulfation which impacts function. CS exhibits a wide range of biological activities. Many experimental and clinical data are available, affirming that CS represents an effective and safe symptomatic treatment of osteoarthritis (OA) with delayed and sustained effects.
Reginster
Jean-Yves
JY
Department of Public Health Economics, University of Liège, Liège, Belgium. jyreginster@ulg.ac.be
Heraud
Florence
F
Zegels
Brigitte
B
Bruyere
Olivier
O
D000818:Animals; D002809:Chondroitin Sulfates / Q000096:biosynthesis / Q000737:chemistry / Q000493:pharmacokinetics / Q000627:therapeutic use; D002986:Clinical Trials as Topic; D018360:Crystallography, X-Ray; D006801:Humans; D008958:Models, Molecular; D008968:Molecular Conformation; D010003:Osteoarthritis / Q000188:drug therapy* / Q000378:metabolism
D002809:Chondroitin Sulfates