title: Narrow CSF space at high convexity and high midline areas in idiopathic normal pressure hydrocephalus detected by axial and coronal MRI.
abstract: BACKGROUND
  The aim of this study was to determine the performance of axial and coronal magnetic resonance imaging (MRI) in detecting the narrowing of the cerebrospinal fluid (CSF) space at the high convexity and high midline areas, which is speculated to be one of the clinical characteristics of idiopathic normal pressure hydrocephalus (iNPH).
  
  
  METHODS
  We retrospectively examined axial and coronal T1-weighted images of 14 iNPH patients and 12 age-matched controls. The narrowness of the CSF space at the high convexity/midline was blindly evaluated by five raters using a continuous confidence rating scale for receiver operating characteristic (ROC) analysis.
  
  
  RESULTS
  Axial and coronal imaging accurately determined the presence of the narrow cisterns/sulci at the high convexity/midline and was capable of predicting probable/definite iNPH with a high degree of accuracy. there were also no significant differences in the detection of this finding between the axial and coronal images.
  
  
  CONCLUSIONS
  Both axial and coronal T1-weighted MRI can detect the narrow CSF space at the high convexity/midline accurately and may therefore facilitate clinicians in choosing a management strategy for iNPH patients.
authors.affiliation: Department of Radiology, Iwate Medical University, 19-1 Uchimaru, Morioka, Japan. masasaki@iwate-med.ac.jp
authors.forename: Makoto
authors.initials: M
authors.lastname: Sasaki
authors.forename: Satoshi
authors.initials: S
authors.lastname: Honda
authors.forename: Tatsuhiko
authors.initials: T
authors.lastname: Yuasa
authors.forename: Akihide
authors.initials: A
authors.lastname: Iwamura
authors.forename: Eri
authors.initials: E
authors.lastname: Shibata
authors.forename: Hideki
authors.initials: H
authors.lastname: Ohba
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002555:Cerebrospinal Fluid; D005260:Female; D006801:Humans; D006850:Hydrocephalus, Normal Pressure / Q000473:pathology*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies