Oppenauer oxidation of secondary alcohols with 1,1,1-trifluoroacetone as hydride acceptor.
1,1,1-Trifluoroacetone (2a) reacts as a hydride-acceptor in the Oppenauer oxidation of secondary alcohols (1) in the presence of diethylethoxyaluminum. The oxidant allows for selective oxidation of secondary alcohols in the presence of primary alcohols.
Mello
Rossella
R
Departamento de Química OrgAnica, Universidad de Valencia, Avda V Andrés Estellés s/n, 46100 Burjassot (Valencia), Spain.
Martínez-Ferrer
Jaime
J
Asensio
Gregorio
G
Gonzalez-Núñez
María Elena
ME