Severe varicella caused by varicella-vaccine strain in a child with significant T-cell dysfunction.
In March 1995, the US Food and Drug Administration approved a live attenuated varicella vaccine for use in healthy children 12 months to 12 years old. We report here an 18-month-old girl with cell-mediated immunodeficiency who developed a severe vaccine-associated rash and clinical evidence of vaccine-associated pneumonia 1 month after inadvertent receipt of varicella vaccine.
Jean-Philippe
Patrick
P
Department of Pediatrics, New York University School of Medicine, New York, New York, USA. jeanphilippep@niaid.nih.gov
Freedman
Abigail
A
Chang
Mary Wu
MW
Steinberg
Sharon P
SP
Gershon
Anne A
AA
LaRussa
Philip S
PS
Borkowsky
William
W
D002644:Chickenpox / Q000175:diagnosis / Q000209:etiology* / Q000276:immunology*; D019433:Chickenpox Vaccine / Q000009:adverse effects*; D005260:Female; D006801:Humans; D007153:Immunologic Deficiency Syndromes / Q000150:complications / Q000276:immunology; D007223:Infant; D013601:T-Lymphocytes / Q000276:immunology*
D019433:Chickenpox Vaccine