One-pot synthesis of carbazoles by palladium-catalyzed N-arylation and oxidative coupling.
One-pot N-arylation and oxidative coupling can be promoted by a common palladium catalyst in the presence of appropriate additives: palladium-catalyzed N-arylation of anilines with aryl triflates under the standard conditions followed by addition of acetic acid under oxygen or air atmosphere afforded various types of functionalized carbazoles in good to excellent yields.
Watanabe
Toshiaki
T
Graduate School of Pharmaceutical Sciences, Kyoto University, Kyoto 606-8501, Japan.
Ueda
Satoshi
S
Inuki
Shinsuke
S
Oishi
Shinya
S
Fujii
Nobutaka
N
Ohno
Hiroaki
H
D000814:Aniline Compounds / Q000737:chemistry*; D002227:Carbazoles / Q000138:chemical synthesis*; D002384:Catalysis; D008698:Mesylates / Q000737:chemistry; D010084:Oxidation-Reduction; D010165:Palladium / Q000737:chemistry
D000814:Aniline Compounds; D002227:Carbazoles; D008698:Mesylates; D010165:Palladium; C012077:trifluoromethanesulfonic acid