Fatal pancreatic panniculitis associated with acute pancreatitis: a case report.
Pancreatic panniculitis is a rare disease in which necrosis of fat in the panniculus and other distant foci occurs in the setting of pancreatic diseases; these diseases include acute and chronic pancreatitis, pancreatic carcinoma, pseudocyst, and other pancreatic diseases. This malady is manifested as tender erythematous nodules on the legs, buttock, or trunk. Histopathologically, it shows the pathognomonic findings of focal subcutaneous fat necrosis and ghost-like anucleated cells with a thick shadowy wall. We herein report a case of fatal pancreatic panniculitis that was associated with acute pancreatitis in a 50-yr-old man. He presented with a 3-week history of multiple tender skin nodules, abdominal pain and distension. Laboratory and radiologic findings revealed acute pancreatitis, and skin biopsy showed pancreatic panniculitis. Despite intensive medical care, he died of multi-organ failure 3 weeks after presentation.
Lee
Woo Sun
WS
Department of Dermatology, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Kim
Mi Yeon
MY
Kim
Sang Woo
SW
Paik
Chang Nyol
CN
Kim
Hyung Ok
HO
Park
Young Min
YM
D000208:Acute Disease; D001706:Biopsy; D004890:Erythema / Q000473:pathology; D017809:Fatal Outcome; D006801:Humans; D008297:Male; D008875:Middle Aged; D009336:Necrosis; D010179:Pancreas / Q000473:pathology; D010195:Pancreatitis / Q000150:complications* / Q000401:mortality*; D019512:Pancreatitis, Alcoholic / Q000175:diagnosis / Q000473:pathology; D015434:Panniculitis / Q000150:complications* / Q000401:mortality*; D012867:Skin / Q000473:pathology; D012871:Skin Diseases / Q000175:diagnosis / Q000473:pathology; D014057:Tomography, X-Ray Computed / Q000379:methods