title: [Antimicrobial resistance in Neisseria gonorrheae in North-East Romania].
abstract: OBJECTIVE
  The emergence of gonococcal isolates with reduced susceptibility or resistance to antimicrobial agents is a significant concern in the whole world. This study is performed to evaluate evolution of antimicrobial resistance patterns of N. gonorrhoeae isolates from north-east Romania.
  
  
  METHODS
  We studied antimicrobial resistance in 81 strains of N. gonorrhoeae isolated from Sexually Transmitted Diseases Clinic in Iasi. The antimicrobial agents tested were Penicillin, Tetracycline, Ciprofloxacin, Cefixime, Ceftriaxone and Spectinomycin.
  
  
  CONCLUSIONS
  As we expected, resistance to Penicillin, Tetracycline and Ciprofloxacin is high and can't no longer be recommended for the treatment of gonorrhea in our area; Ceftriaxone, Cefixime and Spectinomycin should be considered the antimicrobial of choice. We isolated a strain with modified sensitivity to Cefixime, a fact that we should be worry about.
authors.affiliation: Facultatea de Medicină, Disciplina de Microbiologie, Universitatea de Medicină si Farmacie "Gr.T. Popa" Iaşi.
authors.forename: Aida Corina
authors.initials: AC
authors.lastname: Bădescu
authors.forename: Zenaida
authors.initials: Z
authors.lastname: Petrescu
authors.forename: A
authors.initials: A
authors.lastname: Enache
authors.forename: D
authors.initials: D
authors.lastname: Buiuc
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D020682:Cefixime / Q000494:pharmacology; D002443:Ceftriaxone / Q000494:pharmacology; D002939:Ciprofloxacin / Q000494:pharmacology; D024881:Drug Resistance, Bacterial / Q000235:genetics; D004359:Drug Therapy, Combination; D006069:Gonorrhea / Q000188:drug therapy* / Q000453:epidemiology; D006801:Humans; D008826:Microbial Sensitivity Tests; D009344:Neisseria gonorrhoeae / Q000187:drug effects* / Q000235:genetics; D010403:Penicillin Resistance; D010406:Penicillins / Q000494:pharmacology; D012383:Romania / Q000453:epidemiology; D000198:Spectinomycin / Q000494:pharmacology; D013752:Tetracycline / Q000494:pharmacology; D013753:Tetracycline Resistance
chemical_list: D000900:Anti-Bacterial Agents; D010406:Penicillins; D002939:Ciprofloxacin; D002443:Ceftriaxone; D000198:Spectinomycin; D020682:Cefixime; D013752:Tetracycline