title: [Antimicrobial susceptibility of H pylori strains obtained from Paraguayan patients].
abstract: BACKGROUND
  Antimicrobial resistance is one of the main obstacles for an effective eradication of H. pylori infection.
  
  
  OBJECTIVE
  To determine the susceptibility of H. pylori strains obtained from gastric biopsies to metronidazole, clarithromycin and amoxicillin.
  
  
  METHODS
  Susceptibility to metronidazole, clarithromycin and amoxicillin was determined using E-test in 46 isolates of H. pylori obtained from gastric biopsies of 54 adult patients.
  
  
  RESULTS
  Thirty three percent of isolates were resistant to metronidazole and 2% were resistant to clarithromycin and amoxicillin. One isolate was resistant to metronidazole and clarithromycin.
  
  
  CONCLUSIONS
  The antimicrobial susceptibility of these strains of H. pylori obtained from Paraguayan patients, may help to decide the initial therapy to eradicate this infection.
authors.affiliation: Departamento de Microbiología, Instituto de Investigaciones en Ciencias de la Salud, Universidad Nacional de Asunción, Paraguay. microbiologia@iics.una.py
authors.forename: Norma
authors.initials: N
authors.lastname: Fariña
authors.forename: Elena
authors.initials: E
authors.lastname: Kasamatsu
authors.forename: Margarita
authors.initials: M
authors.lastname: Samudio
authors.forename: Miryam
authors.initials: M
authors.lastname: Morán
authors.forename: Rosa
authors.initials: R
authors.lastname: Sanabria
authors.forename: Florentina
authors.initials: F
authors.lastname: Laspina
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000658:Amoxicillin / Q000494:pharmacology; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D017291:Clarithromycin / Q000494:pharmacology; D024901:Drug Resistance, Multiple, Bacterial; D005260:Female; D016481:Helicobacter Infections / Q000382:microbiology*; D016480:Helicobacter pylori / Q000187:drug effects*; D006801:Humans; D008297:Male; D008795:Metronidazole / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D010239:Paraguay
chemical_list: D000900:Anti-Bacterial Agents; D008795:Metronidazole; D000658:Amoxicillin; D017291:Clarithromycin