title: [Studies on chemical constituents of rhizomes of Ligusticum chuanxiong].
abstract: OBJECTIVE
  To study chemical constitutents of the rhizomes of Ligusticum chuanxiong.
  
  
  METHODS
  The rhizomes of L. chuanxiong were extracted with water to afford a water extract which was participated between H2O and EtOAc, n-BuOH, successively. The compounds were isolatedand purified by column chromatography from the EtOAc fraction, and identified based on spectral analyses.
  
  
  RESULTS
  Eleven compounds were isolated from the rhizomes of L. chuanxiong, and structures were characterized as (4S)-p-menth-1-ene4, 7-diol (1), aromadendrane-4alpha, 10beta-diol (2), aromadendrane-4beta, 10alpha-diol (3), aromadendrane-4beta, 10beta-diol (4), augustic acid (5), xiongterpene (6), pregnenolone (7), 3(R), 8(S), 9(Z)-falcarindiol (8), senkyunolide F (9), senkyunolide I (10), 4-hydroxyl-3-butylphthalide (11).
  
  
  CONCLUSIONS
  Compounds 1-5 were obtained from the rhizomes of L. chuanxiong for the first time.
authors.affiliation: State Key Labortatory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, China.
authors.forename: Xin-liang
authors.initials: XL
authors.lastname: Chang
authors.forename: Yun-bao
authors.initials: YB
authors.lastname: Ma
authors.forename: Xue-mei
authors.initials: XM
authors.lastname: Zhang
authors.forename: Zhi-yong
authors.initials: ZY
authors.lastname: Jiang
authors.forename: Ji-jun
authors.initials: JJ
authors.lastname: Chen
mesh_terms: D030004:Ligusticum / Q000737:chemistry*; D009828:Oleanolic Acid / Q000031:analogs & derivatives* / Q000737:chemistry / Q000302:isolation & purification; D010946:Plants, Medicinal / Q000737:chemistry*; D011284:Pregnenolone / Q000737:chemistry / Q000302:isolation & purification; D027343:Rhizome / Q000737:chemistry; D013729:Terpenes / Q000737:chemistry / Q000302:isolation & purification*
chemical_list: D013729:Terpenes; C525519:augustic acid; C525518:p-menth-1-ene-4,7-diol; C478708:xiongterpene; D009828:Oleanolic Acid; D011284:Pregnenolone