Pd(quinoline-8-carboxylate)(2) as a low-priced, phosphine-free catalyst for Heck and Suzuki reactions.
N,O-Bidentate compounds were systematically evaluated as phosphine-free ligands for Pd-catalyzed C-C bond-formation reactions through kinetic measurements. Pd(quinoline-8-carboxylate)2 was identified as one of the most efficient, yet still low-priced, phosphine-free catalysts for Heck as well as Suzuki reactions of unactivated aryl bromides with high turnover numbers up to ca. 10,000.
Cui
Xin
X
Department of Chemistry, Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology, Tsinghua University, Beijing, China.
Li
Juan
J
Zhang
Zhi-Ping
ZP
Fu
Yao
Y
Liu
Lei
L
Guo
Qing-Xiang
QX
D002264:Carboxylic Acids / Q000737:chemistry*; D002384:Catalysis; D002625:Chemistry, Organic / Q000191:economics / Q000379:methods; D006842:Hydrocarbons, Brominated / Q000737:chemistry; D008024:Ligands; D008956:Models, Chemical; D009942:Organometallic Compounds / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry*; D010720:Phosphines / Q000737:chemistry*; D011804:Quinolines / Q000737:chemistry*
D002264:Carboxylic Acids; D006842:Hydrocarbons, Brominated; D008024:Ligands; D009942:Organometallic Compounds; D010720:Phosphines; D011804:Quinolines; D010165:Palladium; C037219:quinoline; C044646:phosphine