title: Thalamic hyperperfusion in verbal hallucination of Parkinsonian patients.
abstract: OBJECTIVE
  We compared brain perfusion image using 3D-SSP analysis of (123)I-IMP SPECT between Parkinson's disease patients with auditory verbal hallucination and those without auditory hallucination.
  
  
  METHODS
  Eighty-three cases with Parkinson's disease were studied. In 6 of these patients, auditory hallucination was noted. Among them, four cases had verbal hallucination and two other cases had elementary hallucination. Auditory hallucination was not found in the other 77 cases.
  
  
  RESULTS
  Right thalamic perfusion was significantly increased in the verbal hallucination group compared to the group that lacked auditory hallucination.
  
  
  CONCLUSIONS
  In Parkinson's disease, the right thalamic hyperactive state may be related to verbal hallucination.
authors.affiliation: Department of Neurology, Sumitomo Hospital, Osaka, Japan. hide0729@kuhp.kyoto-u.ac.jp
authors.forename: Hideaki
authors.initials: H
authors.lastname: Matsui
authors.forename: Kazuto
authors.initials: K
authors.lastname: Nishinaka
authors.forename: Takafumi
authors.initials: T
authors.lastname: Miyoshi
authors.forename: Narihiro
authors.initials: N
authors.lastname: Hara
authors.forename: Masaya
authors.initials: M
authors.lastname: Oda
authors.forename: Tamotsu
authors.initials: T
authors.lastname: Kubori
authors.forename: Fukashi
authors.initials: F
authors.lastname: Udaka
mesh_terms: D000368:Aged; D002560:Cerebrovascular Circulation; D005260:Female; D006212:Hallucinations / Q000145:classification / Q000000981:diagnostic imaging* / Q000209:etiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D010300:Parkinson Disease / Q000150:complications / Q000000981:diagnostic imaging*; D012039:Regional Blood Flow; D013787:Thalamic Nuclei / Q000098:blood supply* / Q000000981:diagnostic imaging*; D015899:Tomography, Emission-Computed, Single-Photon