title: Fenoldopam for acute kidney injury in children.
abstract: We report two cases of children with severe cardiomyopathy requiring treatment with ventricular assist devices who developed acute kidney injury and were treated with fenoldopam. Therapy with fenoldopam appeared successful in one case in that renal replacement therapy was avoided with improvement in urine output and renal function. These are the first reported cases of fenoldopam use in children with acute kidney injury receiving mechanical circulatory support.
authors.affiliation: Department of Pharmacy, Clarian Health Partners-Riley Hospital for Children, 702 Barnhill Drive, Room 1016, Indianapolis, IN 46202, USA. cknoderer@clarian.org
authors.forename: Chad A
authors.initials: CA
authors.lastname: Knoderer
authors.forename: Jeffrey D
authors.initials: JD
authors.lastname: Leiser
authors.forename: Corina
authors.initials: C
authors.lastname: Nailescu
authors.forename: Mark W
authors.initials: MW
authors.lastname: Turrentine
authors.forename: Sharon P
authors.initials: SP
authors.lastname: Andreoli
mesh_terms: D058186:Acute Kidney Injury / Q000188:drug therapy* / Q000209:etiology; D009202:Cardiomyopathies / Q000150:complications; D002648:Child; D018491:Dopamine Agonists / Q000627:therapeutic use*; D005260:Female; D018818:Fenoldopam / Q000627:therapeutic use*; D006801:Humans; D007223:Infant; D008297:Male
chemical_list: D018491:Dopamine Agonists; D018818:Fenoldopam