title: Synthesis of some N4-substituted isatin-3-thiosemicarbazones.
abstract: In this article, we describe a simple and new method for the synthesis of some N4-substituted isatin-3-thiosemicarbazones based on the reactions of the common intermediate, methyl 2-(2-oxo-1,2-dihydro-3H-indol-3-ylidene)-1-hydrazinecarbodithioate, prepared by condensing isatin with methyl 1-hydrazinecarbodithioate, and the readily available amines in essentially a one-step reaction. The synthesized thiosemicarbazones were fully characterized by their physical, analytical, and spectral (IR, 1H-NMR, EIMS) data.
authors.affiliation: Department of Chemistry, Bahauddin Zakariya University, Multan, 60800, Pakistan. pdhpervez@hotmail.com
authors.forename: H
authors.initials: H
authors.lastname: Pervez
authors.forename: M S
authors.initials: MS
authors.lastname: Iqbal
authors.forename: M Y
authors.initials: MY
authors.lastname: Tahir
authors.forename: M I
authors.initials: MI
authors.lastname: Choudhary
authors.forename: K M
authors.initials: KM
authors.lastname: Khan
mesh_terms: D007510:Isatin / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D013055:Spectrophotometry, Infrared; D013882:Thiosemicarbazones / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D013882:Thiosemicarbazones; D007510:Isatin