[Impact of chronic anemia on in-hospital clinical outcome of revascularization in patients with coronary artery disease].
OBJECTIVE
To evaluate the in-hospital clinical outcome of revascularization in patients with coronary artery disease with chronic anemia.


METHODS
Between July 2002 and June 2004, 3 679 patients in Anzhen Hospital Affiliated to Capital University of Medical Sciences were subjected to revascularization [percutaneous coronary intervention (PCI) or coronary artery bypass graft (CABG)] during hospitalization. These patients were divided into anemia group and non-anemia group according to blood hemoglobin (Hb) level [World Health Organization (WHO) standard (male<120 g/L, female<110 g/L) as anemia]. Rates of in-hospital main adverse cardiac and cerebral events (MACCE), including all-cause death, new attack of myocardial infarction, stroke and repeated revascularization were compared between two groups.


RESULTS
There were 426 anemia patients (11.6%) and 3 253 non-anemia patients (88.4%). In-hospital death in the anemia group was higher than that of the non-anemia group [10 cases (2.4%) vs. 64 cases (1.9%), P<0.05]. Rates of MACCE of the anemia group was higher than that of the non-anemia group (4.2% vs. 3.2%, P<0.05). There was no significant difference in rates of new attack of myocardial infarction (0.7% vs. 0.6%), stroke (1.2% vs. 0.4%) and repeated revascularization (0 vs. 0.2%) between two groups (all P>0.05).


CONCLUSIONS
Compared with non-anemia patients, anemia patients with coronary artery disease has higher in-hospital MACCE rate and all-cause mortality.
Que
Bin
B
Department of Cardiology, Beijing Anzhen Hospital, Capital University of Medical Sciences, Beijing 100029, China.
Ma
Chang-sheng
CS
Nie
Shao-ping
SP
Dong
Jian-zeng
JZ
Wu
Xue-si
XS
Liu
Xiao-hui
XH
Lv
Shu-zheng
SZ
Li
Zhi-zhong
ZZ
Chen
Fangi
F
Zhou
Yu-jie
YJ
Gu
Cheng-xiong
CX
Huang
Fang-jiong
FJ
D000740:Anemia / Q000150:complications*; D015906:Angioplasty, Balloon, Coronary; D002908:Chronic Disease; D001026:Coronary Artery Bypass; D003324:Coronary Artery Disease / Q000150:complications / Q000601:surgery*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000209:etiology; D016896:Treatment Outcome