title: Identification of local myocardial repolarization time by bipolar electrode potential.
abstract: OBJECTIVE
  The aim of this study was to investigate whether bipolar electrode potentials (BEPs) reflect local myocardial repolarization dynamics, using computer simulation.
  
  
  METHODS
  Simulated action potential and BEP mapping of myocardial tissue during fibrillation was performed. The BEP was modified to make all the fluctuations have the same polarity. Then, the modified BEP (mBEP) was transformed to "dynamic relative amplitude" (DRA) designed to make all the fluctuations have the similar amplitude.
  
  
  RESULTS
  The repolarization end point corresponded to the end of the repolarization-related small fluctuation that clearly appeared in the DRA of mBEP. Using the DRA of mBEP, we could reproduce the repolarization dynamics in the myocardial tissue during fibrillation.
  
  
  CONCLUSIONS
  The BEP may facilitate identifying the repolarization time. Furthermore, BEP mapping has the possibility that it would be available for evaluating repolarization behavior in myocardial tissue even during fibrillation. The accuracy of activation-recovery interval was also reconfirmed.
authors.affiliation: Department of Medical Technology, Kagawa Prefectural College of Health Sciences, Takamatsu, Japan. hqg04517@nifty.ne.jp
authors.forename: Tsunetoyo
authors.initials: T
authors.lastname: Namba
authors.forename: Takahiro
authors.initials: T
authors.lastname: Todo
authors.forename: Takenori
authors.initials: T
authors.lastname: Yao
authors.forename: Takashi
authors.initials: T
authors.lastname: Ashihara
authors.forename: Ryo
authors.initials: R
authors.lastname: Haraguchi
authors.forename: Kazuo
authors.initials: K
authors.lastname: Nakazawa
authors.forename: Takanori
authors.initials: T
authors.lastname: Ikeda
authors.forename: Tohru
authors.initials: T
authors.lastname: Ohe
mesh_terms: D001281:Atrial Fibrillation / Q000503:physiopathology*; D018780:Body Surface Potential Mapping / Q000379:methods*; D003198:Computer Simulation; D003936:Diagnosis, Computer-Assisted / Q000379:methods*; D004562:Electrocardiography / Q000379:methods*; D004566:Electrodes; D006329:Heart Conduction System / Q000503:physiopathology*; D006801:Humans; D008955:Models, Cardiovascular