title: Identification of a novel sugar 5,7-diacetamido-8-amino-3,5,7,8,9-pentadeoxy-D-glycero-D-galacto-non-2-ulosonic acid present in the lipooligosaccharide of Vibrio parahaemolyticus O3:K6.
abstract: A novel sugar, 5,7-diacetamido-8-amino-3,5,7,8,9-pentadeoxy-D-glycero-D-galacto-non-2-ulosonic acid (NonlA), has been identified as a component of the oligosaccharide (OS) isolated from the lipooligosaccharide (LOS) of the emerging strain of Vibrio parahaemolyticus O3:K6 associated with a global pandemic. In the present study we report the identification and characterization of this novel sugar present in the OS of V. parahaemolyticus O3:K6, using chemical analysis, NMR spectroscopy and mass spectrometry.
authors.affiliation: Department of Chemistry (Carbohydrate), Indian Institute of Chemical Biology, 4, Raja S. C. Mullick Road, Kolkata, 700032, India.
authors.forename: Koushik
authors.initials: K
authors.lastname: Mazumder
authors.forename: Biswa P
authors.initials: BP
authors.lastname: Choudhury
authors.forename: G Balakrish
authors.initials: GB
authors.lastname: Nair
authors.forename: Asish K
authors.initials: AK
authors.lastname: Sen
mesh_terms: D002240:Carbohydrate Sequence; D006027:Glycosides / Q000737:chemistry; D008070:Lipopolysaccharides / Q000737:chemistry* / Q000302:isolation & purification; D009682:Magnetic Resonance Spectroscopy; D008969:Molecular Sequence Data; D009844:Oligosaccharides / Q000737:chemistry / Q000302:isolation & purification; D010766:Phosphorylation; D021241:Spectrometry, Mass, Electrospray Ionization; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; D013400:Sugar Acids / Q000737:chemistry / Q000302:isolation & purification*; D014736:Vibrio parahaemolyticus / Q000737:chemistry*
chemical_list: C539843:5,7-diacetamido-8-amino-3,5,7,8,9-pentadeoxy-glycero-galacto-non-2-ulosonic acid; D006027:Glycosides; D008070:Lipopolysaccharides; D009844:Oligosaccharides; D013400:Sugar Acids; C023023:lipid-linked oligosaccharides