title: Canine histiocytic neoplasia: an overview.
abstract: Canine histiocytic neoplasms include cutaneous histiocytoma, as well as localized and disseminated histiocytic sarcoma. These tumors have variable biologic behavior, although the malignant disorders often have a poor prognosis. Immunohistochemistry plays an essential role in differentiating histiocytic tumors from other neoplasias that may have similar histological appearances. This allows a definitive diagnosis to be established and provides a more accurate prediction of prognosis. This article reviews the biologic behavior, diagnosis, and treatment of histiocytic tumors in the dog.
authors.affiliation: Cancer Treatment Unit, Department of Veterinary Clinical Sciences, School of Veterinary Medicine, Louisiana State University, Skip Bertman Drive, Baton Rouge, Louisiana 70803, USA. afulmer@vetmed.lsu.edu
authors.forename: Amanda K
authors.initials: AK
authors.lastname: Fulmer
authors.forename: Glenna E
authors.initials: GE
authors.lastname: Mauldin
mesh_terms: D000818:Animals; D000943:Antigens, Differentiation; D003713:Dendritic Cells / Q000473:pathology; D004283:Dog Diseases / Q000473:pathology*; D004285:Dogs; D006644:Histiocytes / Q000473:pathology; D054747:Histiocytic Sarcoma / Q000473:pathology / Q000662:veterinary*; D051642:Histiocytoma / Q000473:pathology / Q000662:veterinary*; D007150:Immunohistochemistry / Q000662:veterinary; D008264:Macrophages / Q000473:pathology; D012509:Sarcoma / Q000473:pathology / Q000662:veterinary*
chemical_list: D000943:Antigens, Differentiation