Focal cholesterol granuloma in the anterior mediastinum: [18F]-fluoro-2-deoxy-D-glucose-positron emission tomography and magnetic resonance imaging findings.
Cholesterol granuloma is a foreign-body type granuloma that forms in reaction to cholesterol crystals. We report a rare case of focal cholesterol granuloma in the anterior mediastinum of a 62-year-old asymptomatic man that presented as an indeterminate anterior mediastinal nodule on [18F]-fluoro-2-deoxy-D-glucose-positron emission tomography and computed tomography scans. T1- and T2-weighted magnetic resonance images revealed markedly hypo-intense signals reflecting pathologic hyalinized collagen fibers. Magnetic resonance signal characteristics might be helpful for distinguishing benign cholesterol granulomas from malignant neoplasms.
Fujimoto
Kiminori
K
Department of Radiology, Kurume University School of Medicine, Fukuoka, Japan. kimichan@med.kurume-u.ac.jp
Takamori
Shinzo
S
Yano
Hirohisa
H
Sadohara
Junko
J
Matsuo
Toshihiro
T
Terazaki
Yasuhiro
Y
Ishibashi
Masatoshi
M
Hayabuchi
Naofumi
N
D002784:Cholesterol / Q000378:metabolism*; D019788:Fluorodeoxyglucose F18; D006099:Granuloma / Q000000981:diagnostic imaging*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008482:Mediastinum / Q000000981:diagnostic imaging*; D008875:Middle Aged; D049268:Positron-Emission Tomography; D019275:Radiopharmaceuticals
D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18; D002784:Cholesterol