A simple and cost effective synthesis of 3,11-dimethylnonacosan-2-one, a female sex pheromone of the German cockroach.
A convenient synthesis of 3,11-dimethylnonacosan-2-one (1) is described. Our strategy involves the use of well known C-alkylation and ethyl acetoacetate synthesis reactions as key steps. We expect that this method will prove to be useful for large scale preparation of 1 and modification of dimethylnonacosanones.
Ahn
Kwang-Chan
KC
Department of Chemistry, Institute for Basic Sciences, College of Natural Sciences, Chungbuk National University, Cheongju 361-763, Chungbuk, South Korea.
Jung
Jae-Chul
JC
Park
Oee-Sook
OS
D000818:Animals; D020048:Blattellidae / Q000737:chemistry*; D005260:Female; D007659:Ketones / Q000138:chemical synthesis* / Q000737:chemistry; D012724:Sex Attractants / Q000138:chemical synthesis* / Q000737:chemistry
D007659:Ketones; D012724:Sex Attractants; C011234:3,11-dimethylnonacosanone