A second-generation combined linkage physical map of the human genome.
We have completed a second-generation linkage map that incorporates sequence-based positional information. This new map, the Rutgers Map v.2, includes 28,121 polymorphic markers with physical positions corroborated by recombination-based data. Sex-averaged and sex-specific linkage map distances, along with confidence intervals, have been estimated for all map intervals. In addition, a regression-based smoothed map is provided that facilitates interpolation of positions of unmapped markers on this map. With nearly twice as many markers as our first-generation map, the Rutgers Map continues to be a unique and comprehensive resource for obtaining genetic map information for large sets of polymorphic markers.
Matise
Tara C
TC
Department of Genetics, Rutgers University, Piscataway, New Jersey 08854, USA. matise@biology.rutgers.edu
Chen
Fang
F
Chen
Wenwei
W
De La Vega
Francisco M
FM
Hansen
Mark
M
He
Chunsheng
C
Hyland
Fiona C L
FC
Kennedy
Giulia C
GC
Kong
Xiangyang
X
Murray
Sarah S
SS
Ziegle
Janet S
JS
Stewart
William C L
WC
Buyske
Steven
S
D016001:Confidence Intervals; D005260:Female; D008040:Genetic Linkage; D005819:Genetic Markers; D015894:Genome, Human; D005838:Genotype; D006801:Humans; D008297:Male; D020161:Physical Chromosome Mapping / Q000379:methods / Q000706:statistics & numerical data; D020641:Polymorphism, Single Nucleotide
D005819:Genetic Markers