HBV vaccination in hyperendemic remote tribal areas in India.
Randomly selected 200 subjects were tested for quantitative hepatitis B surface antibody (HBsAb) estimation in a remote tribal area of Arunachal Pradesh, India to measure the protective immunity after vaccination in the backdrop of hyperendemic HBV infection. About 64.6 and 40.0% had HBsAb above 10 mIU/ml in the vaccinated and unvaccinated subjects, respectively (p=0.002, OR: 2.7, 95% CI: 1.5-5.0). Universal vaccination across all age group may be more effective as 63.3% in the unvaccinated group above 15 years did not have protective level of antibody against HBV infection in our study.
Borkakoty
Biswajyoti
B
Mahanta
Jagadish
J
Biswas
Dipankar
D
D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D019353:Endemic Diseases; D005260:Female; D006509:Hepatitis B / Q000453:epidemiology* / Q000517:prevention & control; D006510:Hepatitis B Antibodies / Q000097:blood*; D006514:Hepatitis B Surface Antigens / Q000276:immunology; D017325:Hepatitis B Vaccines / Q000008:administration & dosage*; D006801:Humans; D007194:India / Q000453:epidemiology; D012424:Rural Population; D014611:Vaccination / Q000706:statistics & numerical data*
D006510:Hepatitis B Antibodies; D006514:Hepatitis B Surface Antigens; D017325:Hepatitis B Vaccines