title: Symptom and structure modifying properties of chondroitin sulfate in osteoarthritis.
abstract: Chondroitin sulfate (CS) is a complex carbohydrate polymer with variable sulfation which impacts function. CS exhibits a wide range of biological activities. Many experimental and clinical data are available, affirming that CS represents an effective and safe symptomatic treatment of osteoarthritis (OA) with delayed and sustained effects.
authors.affiliation: Department of Public Health Economics, University of Liège, Liège, Belgium. jyreginster@ulg.ac.be
authors.forename: Jean-Yves
authors.initials: JY
authors.lastname: Reginster
authors.forename: Florence
authors.initials: F
authors.lastname: Heraud
authors.forename: Brigitte
authors.initials: B
authors.lastname: Zegels
authors.forename: Olivier
authors.initials: O
authors.lastname: Bruyere
mesh_terms: D000818:Animals; D002809:Chondroitin Sulfates / Q000096:biosynthesis / Q000737:chemistry / Q000493:pharmacokinetics / Q000627:therapeutic use; D002986:Clinical Trials as Topic; D018360:Crystallography, X-Ray; D006801:Humans; D008958:Models, Molecular; D008968:Molecular Conformation; D010003:Osteoarthritis / Q000188:drug therapy* / Q000378:metabolism
chemical_list: D002809:Chondroitin Sulfates