Analysis of prognostic factors for patients with leiomyoma treated with uterine arterial embolization.
OBJECTIVE
The objective of the study was to describe a clinically useful factors index predicting long-term efficacy of uterine artery embolization (UAE).


METHODS
Newly diagnosed patients with uterine leiomyoma wishing to retain their uterus underwent UAE at our institution. Clinical demographics and 4 prognostic factors were recovered from the medical record. A regrowth-free interval (RFI) was calculated for all patients based on leiomyoma regrowth or recurrence of any previously reported symptoms. RFI by prognostic factor was analyzed by the Kaplan-Meier method.


RESULTS
Forty-three patients were identified. Two prognostic factors were identified by multivariate analysis: vascularity (dichotomized as hypervascular vs hypovascular; RFI at 2 years, 80% vs 20%, P = .001) and number of nodules (solitary vs multiple; RFI at 2 years, 72% vs 25% at 2 years, P = .001)


CONCLUSIONS
UAE success may be predicted by 2 preoperative parameters. Further investigation is warranted.
Isonishi
Seiji
S
Department of Obstetrics and Gynecology, Jikei University School of Medicine, Aoto Hospital, Tokyo, Japan. isonishi@jikei.ac.jp
Coleman
Robert L
RL
Hirama
Masanori
M
Iida
Yasushi
Y
Kitai
Satomi
S
Nagase
Masanori
M
Ochiai
Kazuhiko
K
D000328:Adult; D001158:Arteries; D004621:Embolization, Therapeutic; D005260:Female; D006801:Humans; D007889:Leiomyoma / Q000098:blood supply* / Q000473:pathology / Q000628:therapy*; D008875:Middle Aged; D011379:Prognosis; D014594:Uterine Neoplasms / Q000098:blood supply* / Q000473:pathology / Q000628:therapy*; D014599:Uterus / Q000098:blood supply*