title: Brucellosis-induced immune thrombocytopenia mimicking ITP: a report of seven cases.
abstract: Brucellosis continues to be an important cause of fever in underdeveloped countries and in rural areas of developed world. It is a multisystemic disease, associated with wide variety of symptoms. A wide variety of symptoms, including haematological abnormalities, such as anaemia, thrombocytopenia, pancytopenia, dissemine intravascular coagulation and leucopoenia could be seen, all of which are more common than usually thought. In this short study, we present a relatively uncommon haematological manifestation that of isolated thrombocytopenia mimicking idiopathic thrombocytopenic purpura, which we observed in seven of 114 patients who were diagnosed with brucellosis in our hospital over a 2-year period. Having given brucellosis treatment with rifampicin and doxycycline, complete remission was achieved and thrombocyte count returned to normal in all cases.
authors.affiliation: Department of Haematology, Gaziantep University School of Medicine, Gaziantep, Turkey. mmyilmaz@gantep.edu.tr
authors.forename: M
authors.initials: M
authors.lastname: Yilmaz
authors.forename: O
authors.initials: O
authors.lastname: Tiryaki
authors.forename: M
authors.initials: M
authors.lastname: Namiduru
authors.forename: V
authors.initials: V
authors.lastname: Okan
authors.forename: A
authors.initials: A
authors.lastname: Oguz
authors.forename: H
authors.initials: H
authors.lastname: Buyukhatipoglu
authors.forename: I
authors.initials: I
authors.lastname: Karaoglan
authors.forename: B
authors.initials: B
authors.lastname: Yilmaz
mesh_terms: D000328:Adult; D000368:Aged; D000904:Antibiotics, Antitubercular / Q000008:administration & dosage; D002006:Brucellosis / Q000175:diagnosis* / Q000188:drug therapy; D003937:Diagnosis, Differential; D004318:Doxycycline / Q000008:administration & dosage; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D016553:Purpura, Thrombocytopenic, Idiopathic / Q000175:diagnosis* / Q000188:drug therapy; D012293:Rifampin / Q000008:administration & dosage; D013921:Thrombocytopenia / Q000175:diagnosis* / Q000188:drug therapy
chemical_list: D000904:Antibiotics, Antitubercular; D004318:Doxycycline; D012293:Rifampin