title: Amphiphilic helical peptides containing two acridine moieties display picomolar affinity toward HIV-1 RRE and TAR.
authors.affiliation: Department of Chemistry & Education, Seoul National University, Seoul 151-742, Korea.
authors.forename: Yeongran
authors.initials: Y
authors.lastname: Lee
authors.forename: Soonsil
authors.initials: S
authors.lastname: Hyun
authors.forename: Hyun Jin
authors.initials: HJ
authors.lastname: Kim
authors.forename: Jaehoon
authors.initials: J
authors.lastname: Yu
mesh_terms: D000166:Acridines / Q000737:chemistry*; D019380:Anti-HIV Agents / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D015497:HIV-1 / Q000187:drug effects* / Q000378:metabolism; D010455:Peptides / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D011485:Protein Binding; D011487:Protein Conformation; D016601:RNA-Binding Proteins / Q000096:biosynthesis*; D020218:Response Elements; D013501:Surface-Active Agents / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D014779:Virus Replication / Q000187:drug effects; D000099253:Trans-Activation Responsive RNA-Binding Protein
chemical_list: D000166:Acridines; D019380:Anti-HIV Agents; D010455:Peptides; D016601:RNA-Binding Proteins; D013501:Surface-Active Agents; D000099253:Trans-Activation Responsive RNA-Binding Protein