Paraneoplastic leukocytoclastic vasculitis in chronic lymphoid leukemia.
A 50-year-old female who was a known case of chronic lymphoid leukemia (CLL) developed ecchymoses, purpuric spots with papules, some nodules (1-3 mm) and crusts all over the body associated with severe burning and itching along with exaggeration of CLL. The lesions were more prominent on lower limbs and face. Skin biopsy was reported as leukocytoclastic vasculitis. These lesions regressed after treatment with leukeran and glucocorticoids.
Yadav
B S
BS
Department of Radiotherapy, PGIMER, Chandigarh, India. drbudhi@gmail.com
Sharma
S C
SC
Kapoor
R K
RK
D018906:Antineoplastic Agents, Alkylating / Q000008:administration & dosage; D018931:Antineoplastic Agents, Hormonal / Q000008:administration & dosage; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002699:Chlorambucil / Q000008:administration & dosage; D005260:Female; D006801:Humans; D008228:Lymphoma, Non-Hodgkin / Q000150:complications* / Q000188:drug therapy; D008875:Middle Aged; D010257:Paraneoplastic Syndromes / Q000209:etiology* / Q000503:physiopathology; D011239:Prednisolone / Q000008:administration & dosage; D018366:Vasculitis, Leukocytoclastic, Cutaneous / Q000209:etiology* / Q000503:physiopathology
D018906:Antineoplastic Agents, Alkylating; D018931:Antineoplastic Agents, Hormonal; D002699:Chlorambucil; D011239:Prednisolone