Efficient Ce(NO3)3 x 6H2O-catalyzed solvent-free synthesis of 3,4-dihydropyrimidin-2(1H)-ones.
Cerium(III) nitrate hexahydrate efficiently catalyzes the three-component Biginelli reaction under solvent-free conditions of an aldehyde, a beta-keto ester or beta-diketone and urea or thiourea to afford the corresponding 3,4-dihydropyrimidin-2(1H)-ones or -thiones in excellent yields.
Adib
Mehdi
M
School of Chemistry, University College of Science, University of Tehran, P. O. Box 14155-6455, Tehran, Iran. madib@khayam.ut.ac.ir
Ghanbary
Khadijeh
K
Mostofi
Manizheh
M
Ganjali
Mohammad Reza
MR
D002384:Catalysis; D002563:Cerium / Q000737:chemistry*; D011744:Pyrimidinones / Q000138:chemical synthesis* / Q000737:chemistry; D012997:Solvents / Q000737:chemistry*; D014867:Water / Q000737:chemistry*
D011744:Pyrimidinones; D012997:Solvents; D014867:Water; C032786:cerium nitrate; D002563:Cerium