[pH value and potassium level of diagnostic peritoneal lavage fluid in the early diagnosis of acute mesenteric ischemia secondary to arterial occlusion in rats].
BACKGROUND
In this experimental study we evaluated the pH and potassium changes of the peritoneal irrigation fluid in the early phase of mesenteric ischemia.


METHODS
The Wistar albino rats were assigned randomly to 5 equal groups of 10 rats: sham operation, 30, 60, 120 and 180 minutes ischemia by arterial occlusion. We enregistred the ranges of pH and potassium in peritoneal irrigation fluid and serum pH.


RESULTS
Lower pH and increased potassium levels in peritoneal irrigation fluid were observed in 30 and 60 min ischemia groups. In 120 and 180 ischemia groups the level of pH continued to be lower and potassium level increased gradually, the serum pH were markedly lower in these groups. Histological analysis showed a positive correlation between the intestinal injury and ischemia time.


CONCLUSIONS
In contrast to sham group, increase in potassium and decrease in in pH levels in peritoneal irrigation fluid were seen in 30 and 60 min ischemia groups. The decrease of serum pH was enregistred after 120 min of ischemia. In early phase the measurement of potassium and pH in peritoneal irrigation fluid may be an early diagnostic tool for mesenteric ischemia.
Gönüllü
Doğan
D
Department of General Surgery, Taksim Training and Research Hospital, Istanbul, Turkey. dogangonullu@yahoo.com
Yankol
Yücel
Y
Işiman
Ferruh
F
Akyildiz Iğdem
Ayşenur
A
Yücel
Osman
O
Köksoy
Ferda Nihat
FN
D000818:Animals; D001202:Ascitic Fluid / Q000737:chemistry*; D006863:Hydrogen-Ion Concentration; D007511:Ischemia / Q000097:blood / Q000175:diagnosis* / Q000503:physiopathology; D008641:Mesenteric Vascular Occlusion / Q000097:blood / Q000175:diagnosis* / Q000503:physiopathology; D008643:Mesentery / Q000098:blood supply*; D010533:Peritoneal Lavage; D011188:Potassium / Q000032:analysis; D011237:Predictive Value of Tests; D051381:Rats; D017208:Rats, Wistar
D011188:Potassium