title: [Clinical study on a randomized, double-blind control of Shenwu gelatin capsule in treatment of mild cognitive impairment].
abstract: OBJECTIVE
  To evaluate the effectiveness of Shenwu gelatin capsule (compound Chinese ginseng and fleeceflower root etc) in the treatment on senile mild cognitive impairment.
  
  
  METHODS
  166 patients meeting criteria for mild cognitive impairment were selected from patients in Dongzhimen Hospital and were randomly assigned into a treatment group (n = 83 cases), given 5 capsules of Shenwu gelatin capsule, and a positive control group (n = 83 cases) , given 2 capsules of aniracetam with 3 placebo capsules. All subjects took this medication 3 times a day for 3 months, double-blind and double-moulding control were used in this study. At a baseline and end (three months later), all subjects were assessed using a battery consisting of MMSE and clinical memory scale (CMS).
  
  
  RESULTS
  Both Shenwu gelatin capsule and aniracetam can remarkably increase the score of memory quotient (MQ), P < 0. 01. They have the similarly effectiveness, there are no statistical difference between the two groups in effectiveness of increasing memory scores.
  
  
  CONCLUSIONS
  Shenwu gelatin capsule has certain effects on mild cognitive impairment.
authors.affiliation: Dongzhimen Hospital of Beijing University of Chinese Medicine, Beijing 100700, China.
authors.forename: Jian
authors.initials: J
authors.lastname: Zhong
authors.forename: Jin-zhou
authors.initials: JZ
authors.lastname: Tian
authors.forename: Ai-hua
authors.initials: AH
authors.lastname: Zhu
authors.forename: Cheng-zhi
authors.initials: CZ
authors.lastname: Yang
mesh_terms: D029023:Acorus / Q000737:chemistry; D000368:Aged; D002214:Capsules; D003071:Cognition / Q000187:drug effects; D003072:Cognition Disorders / Q000188:drug therapy* / Q000503:physiopathology / Q000523:psychology; D004311:Double-Blind Method; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage / Q000302:isolation & purification / Q000627:therapeutic use*; D005260:Female; D005780:Gelatin; D006801:Humans; D008297:Male; D008568:Memory / Q000187:drug effects; D008875:Middle Aged; D005894:Panax / Q000737:chemistry; D008517:Phytotherapy; D010946:Plants, Medicinal / Q000737:chemistry*; D028502:Polygonum / Q000737:chemistry; D016896:Treatment Outcome
chemical_list: D002214:Capsules; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal; C532978:shenwu; D005780:Gelatin