Osteoclast-like giant-cell tumor of the parotid with salivary duct carcinoma: case report and cytologic, histologic, and immunohistochemical findings.
Primary giant-cell tumor of the salivary gland is a rare lesion with an incompletely characterized histogenesis. To the best of our knowledge, only 16 cases have been previously documented in the English-language literature. We report a new case, which occurred in a 75-year-old man who presented with a parotid mass and cervical lymphadenopathy. The patient underwent a left total parotidectomy and cervical lymph node dissection. As far as we know, ours is the only reported case of a primary giant-cell tumor of the salivary gland in which the patient presented with lymph node metastasis. Because so little is known about giant-cell tumor of the salivary gland, we use the occasion of this case report to describe the cytologic, histologic, and immunohistochemical characteristics that we observed.
Kadivar
Maryam
M
Department of Pathology, Iran University of Medical Sciences, Tehran, Iran. dmkadivar@yahoo.com
Nilipour
Yalda
Y
Sadeghipour
Alireza
A
D000368:Aged; D002277:Carcinoma / Q000276:immunology* / Q000473:pathology* / Q000601:surgery; D005870:Giant Cell Tumors / Q000276:immunology* / Q000473:pathology* / Q000601:surgery; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D010010:Osteoclasts / Q000473:pathology*; D010307:Parotid Neoplasms / Q000276:immunology / Q000473:pathology / Q000601:surgery; D012468:Salivary Gland Neoplasms / Q000276:immunology* / Q000473:pathology* / Q000601:surgery