Immune reconstitution inflammatory syndrome presenting as pericarditis and pericardial effusion.
Immune reconstitution inflammatory syndrome (IRIS) affects 30-43% of HIV and tuberculosis (TB) co-infected patients after starting highly active antiretroviral therapy (HAART). Pericarditis and pericardial effusion are rare manifestations of IRIS. We report a case of HIV-TB related IRIS that developed pericardial involvement. This complication resolved after treatment with ibuprofen. Antituberculous treatment and HAART were not interrupted.
Rapose
Alwyn
A
Division of Infectious Diseases, Department of Internal Medicine, University of Texas Medical Branch, Galveston, TX 77555-0435, USA. alrapose@utmb.edu
Sarvat
Bilal
B
Sarria
Juan C
JC
D000328:Adult; D023241:Antiretroviral Therapy, Highly Active; D005260:Female; D015658:HIV Infections / Q000188:drug therapy / Q000453:epidemiology; D006801:Humans; D054019:Immune Reconstitution Inflammatory Syndrome / Q000175:diagnosis*; D010490:Pericardial Effusion / Q000175:diagnosis*; D010493:Pericarditis / Q000175:diagnosis*; D014057:Tomography, X-Ray Computed; D014376:Tuberculosis / Q000453:epidemiology