title: Five novel prenylated xanthones from Resina Garciniae.
abstract: Fourteen prenylated xanthone derivatives were isolated from gamboge, the dry latex of Garcinia hanburyi, and their structures were elucidated by a detailed spectroscopic analysis. Five of them, isogambogenic acid (1), desoxymorellinin (2), 10-methoxygambogenic acid (3), 10-methoxygambogic acid (4) and 10-ethoxy gambogic acid (5), are new compounds. All of them showed potent cytotoxicity against HL-60, SMMC-7721 and BGC-83 cells.
authors.affiliation: Department of Phytochemistry, China Pharmaceutical University, Nanjing, China.
authors.forename: Feng
authors.initials: F
authors.lastname: Feng
authors.forename: Wen-Yuan
authors.initials: WY
authors.lastname: Liu
authors.forename: You-Sheng
authors.initials: YS
authors.lastname: Chen
authors.forename: Qing-Long
authors.initials: QL
authors.lastname: Guo
authors.forename: Qi-Dong
authors.initials: QD
authors.lastname: You
mesh_terms: D004354:Drug Screening Assays, Antitumor; D029760:Garcinia / Q000737:chemistry*; D015394:Molecular Structure; D013057:Spectrum Analysis / Q000379:methods; D044004:Xanthones / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
chemical_list: D044004:Xanthones