title: Surgical site infections after colorectal surgery: do risk factors vary depending on the type of infection considered?
abstract: BACKGROUND
  The purpose of this study was to compare risk factors for the development of incisional versus organ/space infections in patients undergoing colorectal surgery.
  
  
  METHODS
  An institutional review board-approved retrospective review was performed examining a 4-year period (January 2002 to December 2005). Patients were included if they had undergone abdominal operations (open or laparoscopic) in which the colon/rectum was surgically manipulated. Patients were excluded if the surgical wound was not closed primarily. A standardized definition of incisional and organ/space infection was employed.
  
  
  RESULTS
  A total of 428 operations were performed. Overall, 105 infections were identified (25%); 73 involved the incision and 32 were classified as organ/space. Multivariate analysis suggested that incisional infection was independently associated with body mass index (odds ratio [OR], 1.07; 95% confidence interval [CI], 1.02-1.11) and creation/revision/reversal of an ostomy (OR, 2.2; 95% CI, 1.3-3.9). Organ/space infection was independently associated with perioperative transfusion (OR, 2.3; 95% CI, 1.1-5.5) and with previous abdominal surgery (OR, 2.5; 95% CI, 1.2-5.3).
  
  
  CONCLUSIONS
  Factors associated with infection differed based on the type of surgical site infection being considered. The lack of overlap between factors associated with incisional infection and organ/space infection suggests that separate risk models and treatment strategies should be developed.
authors.affiliation: Department of Surgery, University of Texas, Southwestern Medical Center, Dallas, TX, USA.
authors.forename: Jennifer
authors.initials: J
authors.lastname: Blumetti
authors.forename: Myda
authors.initials: M
authors.lastname: Luu
authors.forename: George
authors.initials: G
authors.lastname: Sarosi
authors.forename: Kathleen
authors.initials: K
authors.lastname: Hartless
authors.forename: Jackie
authors.initials: J
authors.lastname: McFarlin
authors.forename: Betty
authors.initials: B
authors.lastname: Parker
authors.forename: Sean
authors.initials: S
authors.lastname: Dineen
authors.forename: Sergio
authors.initials: S
authors.lastname: Huerta
authors.forename: Massimo
authors.initials: M
authors.lastname: Asolati
authors.forename: Esteban
authors.initials: E
authors.lastname: Varela
authors.forename: Thomas
authors.initials: T
authors.lastname: Anthony
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001803:Blood Transfusion / Q000706:statistics & numerical data; D015992:Body Mass Index; D003106:Colon / Q000601:surgery; D013505:Digestive System Surgical Procedures / Q000706:statistics & numerical data*; D005260:Female; D006801:Humans; D010535:Laparoscopy / Q000706:statistics & numerical data*; D008297:Male; D008875:Middle Aged; D009017:Morbidity; D015999:Multivariate Analysis; D010030:Ostomy / Q000706:statistics & numerical data*; D012007:Rectum / Q000601:surgery; D012086:Reoperation / Q000706:statistics & numerical data; D012189:Retrospective Studies; D012307:Risk Factors; D013530:Surgical Wound Infection / Q000453:epidemiology*