[Influence of embryo transfer depth on in vitro fertilization and embryo transfer outcomes].
OBJECTIVE
To investigate the influence of transfer distance from the fundus on clinical pregnancy rate and implantation rate in in vitro fertilization and embryo transfer.


METHODS
A total of 98 patients (108 cycles) undergoing ultrasound-guided embryo transfer were divided into two groups according to the distance between the tip of catheter and the uterine fundus: group A: > or = 5 - < 10 mm, group B: > or = 10 - < or = 15 mm.


RESULTS
Clinical pregnancy rate and implantation rate were significantly higher in group B compared with group A [44 % (23/52) vs 25% (14/56), 24% (28/115) vs 14% (17/121), P < 0.05]. The multiple pregnancy rate, ectopic rate and miscarriage rate were similar in the two groups (P > 0.05).


CONCLUSIONS
The depth of the embryo replacement into the uterine cavity may influence pregnancy rate and implantation rate.
Zhao
Xiao-hui
XH
Center of Reproductive Medicine, Tianjin Medical University General Hospital, Tianjin 300052, China. zxh0116@163.com
Song
Xue-ru
XR
Sui
Xiao-lin
XL
Bai
Xiao-hong
XH
D000328:Adult; D010064:Embryo Implantation; D004624:Embryo Transfer; D005260:Female; D005307:Fertilization in Vitro / Q000379:methods*; D006801:Humans; D007247:Infertility, Female / Q000503:physiopathology / Q000628:therapy; D011247:Pregnancy; D011256:Pregnancy Outcome; D018873:Pregnancy Rate; D012189:Retrospective Studies; D014463:Ultrasonography / Q000379:methods; D014599:Uterus / Q000000981:diagnostic imaging / Q000503:physiopathology*