[Vigabatrin toxic retinopathy].
METHODS
We report a case of a 63-year-old patient with epilepsy treated with vigabatrin, who was seen because of diminished visual acuity. Examination showed a toxic retinopathy with optic nerve pallor and severely constricted visual fields. One year after cessation of the vigabatrin, no change in the perimetric constriction had occurred.


CONCLUSIONS
Ophthalmologists and neurologists need to be aware of the possibility of retinal toxicity due to the use of vigabatrin. It is still unclear as to which ophthalmologic assessment is of the most diagnostic value; however visual field examination covering the peripheral 60 degrees and optical coherence tomography could be most useful for the screening of patients using this agent.
Suárez-Baraza
J
J
Hospital Universitario 12 de Octubre, Madrid, Spain. emartinbo@hotmail.com
Suárez-Parra
S
S
D000927:Anticonvulsants / Q000009:adverse effects*; D004596:Electroretinography; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D012164:Retinal Diseases / Q000139:chemically induced*; D013997:Time Factors; D041623:Tomography, Optical Coherence; D020888:Vigabatrin / Q000009:adverse effects*; D014792:Visual Acuity; D058609:Visual Field Tests; D014794:Visual Fields
D000927:Anticonvulsants; D020888:Vigabatrin