title: The natural course of bicuspid aortic valve in athletes.
abstract: The purpose of this study was to evaluate the impact of a long-term athletic training on the clinical course of bicuspid aortic valve. A group of 81 athletes (73 M, 8 F, 22.7 +/- 5.6 years) with bicuspid aortic valve was collected. Based on clinical and echocardiographic criteria, athletes were initially divided into 2 groups: the low-risk (51 athletes) and the high-risk group (30 athletes). The high-risk athletes were disqualified from training and competitions after the first evaluation. Over the follow-up period, all of them showed significant worsening of morphologic and hemodynamic features of bicuspid aortic valve; two underwent surgical valvular repair and one of them died suddenly. Over the same period, six of the initially low-risk athletes (7%) showed significant worsening of morphologic features of bicuspid aortic valve and/or incidence of symptoms which led to their disqualification from competition. At the end of follow-up, we observed that in high-risk subjects the progression of valvular disease occurred independently from the former athletic activity and that the majority of athletes with mild bicuspid aortic valve had a benign clinical course. However, athletes with bicuspid aortic valve should be viewed with caution, and continued clinical surveillance would be mandatory.
authors.affiliation: Department of Cardiology, National Institute of Sport Medicine, Rome, Italy. antoniospataro@yahoo.it
authors.forename: A
authors.initials: A
authors.lastname: Spataro
authors.forename: A
authors.initials: A
authors.lastname: Pelliccia
authors.forename: M
authors.initials: M
authors.lastname: Rizzo
authors.forename: A
authors.initials: A
authors.lastname: Biffi
authors.forename: G
authors.initials: G
authors.lastname: Masazza
authors.forename: F
authors.initials: F
authors.lastname: Pigozzi
mesh_terms: D000293:Adolescent; D000328:Adult; D001021:Aortic Valve / Q000002:abnormalities*; D002648:Child; D004452:Echocardiography; D005260:Female; D005500:Follow-Up Studies; D006349:Heart Valve Diseases / Q000503:physiopathology*; D006801:Humans; D008297:Male; D012307:Risk Factors; D013177:Sports; D013997:Time Factors