title: Novel amphiphilic cyclic oligosaccharides: synthesis and self-aggregation properties.
abstract: Novel amphiphilic cyclic disaccharide analogues, in which the saccharide units are connected through stable phosphodiester linkages (CyPLOS, Cyclic Phosphate-Linked OligoSaccharides) and decorated with long lipophilic tentacles at the 2- and 3-OH moieties, have been synthesized. Their propensity to self-aggregation has been investigated by means of 1H and 31P NMR experiments, making it possible to determine for these macrocycles critical aggregation concentration values in the millimolar range.
authors.affiliation: Dipartimento di Chimica Organica e Biochimica, Università Federico II di Napoli, Complesso Universitario di Monte S. Angelo, via Cintia, 4, I-80126 Napoli, Italy.
authors.forename: Cinzia
authors.initials: C
authors.lastname: Coppola
authors.forename: Vittorio
authors.initials: V
authors.lastname: Saggiomo
authors.forename: Giovanni
authors.initials: G
authors.lastname: Di Fabio
authors.forename: Lorenzo
authors.initials: L
authors.lastname: De Napoli
authors.forename: Daniela
authors.initials: D
authors.lastname: Montesarchio
mesh_terms: D002236:Carbohydrate Conformation; D009682:Magnetic Resonance Spectroscopy / Q000379:methods; D009844:Oligosaccharides / Q000138:chemical synthesis* / Q000737:chemistry*; D013237:Stereoisomerism; D013501:Surface-Active Agents / Q000138:chemical synthesis* / Q000737:chemistry*
chemical_list: D009844:Oligosaccharides; D013501:Surface-Active Agents