Lymphocytic reaction to ultraviolet radiation on rabbit conjunctiva.
We examined the clinical and histological effects of controlled UV radiation on the conjunctiva and cornea of rabbit eyes by duration of exposure (0.5-4 hours daily for 5 consecutive days). Longer UV exposure (day 1-day 5) was associated with increased conjunctival redness, corneal erosion, edema and opacity. This study shows that UV irradiation leads to clinical and histological changes which may reflect an immune reaction to damaged epithelial cells.
Gaton
Dan D
DD
Department of Ophthalmology, Rabin Medical Center, Beilinson Campus, Petah Tiqwa, Israel.
Lichter
Henia
H
Avisar
Inbal
I
Slodovinic
Dan
D
Solomon
Arieh S
AS
D000818:Animals; D002386:Cataract / Q000209:etiology; D003228:Conjunctiva / Q000473:pathology* / Q000528:radiation effects*; D003229:Conjunctival Diseases / Q000209:etiology / Q000473:pathology; D003315:Cornea / Q000473:pathology* / Q000528:radiation effects*; D003316:Corneal Diseases / Q000209:etiology / Q000473:pathology; D015715:Corneal Edema / Q000209:etiology; D004307:Dose-Response Relationship, Radiation; D008214:Lymphocytes / Q000473:pathology*; D011817:Rabbits; D012720:Severity of Illness Index; D013997:Time Factors; D014466:Ultraviolet Rays / Q000009:adverse effects*