WOMBAT: a tool for mixed model analyses in quantitative genetics by restricted maximum likelihood (REML).
WOMBAT is a software package for quantitative genetic analyses of continuous traits, fitting a linear, mixed model; estimates of covariance components and the resulting genetic parameters are obtained by restricted maximum likelihood. A wide range of models, comprising numerous traits, multiple fixed and random effects, selected genetic covariance structures, random regression models and reduced rank estimation are accommodated. WOMBAT employs up-to-date numerical and computational methods. Together with the use of efficient compilers, this generates fast executable programs, suitable for large scale analyses. Use of WOMBAT is illustrated for a bivariate analysis. The package consists of the executable program, available for LINUX and WINDOWS environments, manual and a set of worked example, and can be downloaded free of charge from (http://agbu. une.edu.au/~kmeyer/wombat.html).
Meyer
Karin
K
Animal Genetics and Breeding Unit, University of New England, Armidale, NSW, Australia. kmeyer@didgeridoo.une.edu.au
D000818:Animals; D016013:Likelihood Functions; D051379:Mice; D008957:Models, Genetic; D012984:Software