title: Coupling reaction of alkyl chlorides with silyl enolates catalyzed by indium trihalide.
abstract: Indium(III) halide catalyzed not only the coupling of alkyl chlorides with silyl enolates derived from esters, ketones, and aldehydes to give a variety of alpha-alkylated carbonyl compounds but also one-pot, three-component reactions of aldehyde enolate, alkyl chloride, and allylsilane or alkynylsilane.
authors.affiliation: Department of Applied Chemistry, Center for Atomic and Molecular Technologies (CAMT), Graduate School of Engineering, Osaka University, 2-1 Yamadaoka, Suita, Osaka 565-0871, Japan.
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Nishimoto
authors.forename: Makoto
authors.initials: M
authors.lastname: Yasuda
authors.forename: Akio
authors.initials: A
authors.lastname: Baba
mesh_terms: D000447:Aldehydes / Q000138:chemical synthesis / Q000737:chemistry; D000577:Amides / Q000138:chemical synthesis / Q000737:chemistry; D001965:Bromides / Q000737:chemistry*; D002384:Catalysis; D004952:Esters / Q000138:chemical synthesis / Q000737:chemistry; D006843:Hydrocarbons, Chlorinated / Q000737:chemistry*; D007204:Indium / Q000737:chemistry*; D007659:Ketones / Q000138:chemical synthesis / Q000737:chemistry; D015394:Molecular Structure; D012821:Silanes / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D000447:Aldehydes; D000577:Amides; D001965:Bromides; D004952:Esters; D006843:Hydrocarbons, Chlorinated; D007659:Ketones; D012821:Silanes; D007204:Indium