title: [Leptospirosis in children. Clinico-biological and therapeutic aspects for the cases hospitalised between 1992-2005].
abstract: The aim of the study is that of showing the prevalence of the disease in childhood in our county.
  
  
  METHODS
  We studied the observation files of the patients admitted in our unit in between 1992 and 2005 comprised in the 0-15 year old age bracket, noticing all the epidemiological, clinical and therapeutic aspects.
  
  
  RESULTS
  In the above mentioned period, 16 patients from the 0-15 year old group (3.12% of all the patients suffering from leptospirosis) were admitted in our clinic. Male (93.75%) and suburban area (60%) were dominant; 11-15 year old group was represented in 87.5% cases; the prevalence was observed during the summer (11 cases) and during 1999 (6 cases); the meningeal signs were noticed in 5 cases and jaundice for 3 children; the most frequent agent was L. icterohaemorrhagiae--7 cases. The etiological treatment was performed for 14 cases with betalactamines for 7.4 days in average; no lethal cases were noticed.
  
  
  CONCLUSIONS
  In the case of Iaşi County, leptospirosis is a clinico-biological entity considered in the diagnosis of the jaundice, meningeal and febrile syndromes in children.
authors.affiliation: Facultatea de Medicină, Clinica Boli Infecţioase, Universitatea de Medicina si Farmacie "Gr.T. Popa" Iaşi.
authors.forename: Carmen
authors.initials: C
authors.lastname: Manciuc
authors.forename: Carmen
authors.initials: C
authors.lastname: Dorobăţ
authors.forename: M
authors.initials: M
authors.lastname: Hurmuzache
authors.forename: V
authors.initials: V
authors.lastname: Luca
authors.forename: Doina
authors.initials: D
authors.lastname: Mihalache
authors.forename: Oana
authors.initials: O
authors.lastname: Grigorescu
mesh_terms: D000293:Adolescent; D000667:Ampicillin / Q000627:therapeutic use; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D004359:Drug Therapy, Combination; D005260:Female; D006760:Hospitalization / Q000706:statistics & numerical data*; D006801:Humans; D007231:Infant, Newborn; D007919:Leptospira / Q000302:isolation & purification; D007922:Leptospirosis / Q000175:diagnosis* / Q000188:drug therapy / Q000453:epidemiology*; D008297:Male; D008499:Medical Records; D010400:Penicillin G / Q000627:therapeutic use; D015995:Prevalence; D012189:Retrospective Studies; D012383:Romania / Q000453:epidemiology; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents; D000667:Ampicillin; D010400:Penicillin G