Seroprevalence of Entamoeba histolytica infection in HIV-infected patients in China.
Seroprevalence of Entamoeba histolytica infection in HIV-infected individuals from Shanghai city, Anhui province, and Henan province, China, was examined by enzyme-linked immunosorbent assay using crude antigen and a recombinant surface antigen, C-Igl, of the parasite. In 215 HIV-infected individuals, the positive rates for these antigens were 12.1% and 7.9%, respectively; these rates were significantly higher than the rates of 3.1% and 0.5%, respectively, in 191 patients with gastrointestinal symptoms who were not infected with HIV. There was no significant difference in seropositivity to E. histolytica between men and women. Seropositivity in HIV-infected individuals was higher in patients with a CD4(+) T cell count of < 200/microL. This is the first report showing a higher seroprevalence of E. histolytica infection in HIV-infected patients in China. Our results also suggest that HIV infection is a risk factor for infection with E. histolytica.
Chen
Yi
Y
Department of Medical Microbiology and Parasitology, Fudan University School of Medicine, Shanghai, China.
Zhang
Yunzhi
Y
Yang
Bin
B
Qi
Tangkai
T
Lu
Hongzhou
H
Cheng
Xunjia
X
Tachibana
Hiroshi
H
D017088:AIDS-Related Opportunistic Infections / Q000097:blood / Q000276:immunology; D000328:Adult; D000818:Animals; D000913:Antibodies, Protozoan / Q000097:blood*; D002681:China / Q000453:epidemiology; D004404:Dysentery, Amebic / Q000097:blood / Q000453:epidemiology* / Q000276:immunology; D004748:Entamoeba histolytica / Q000276:immunology* / Q000502:physiology; D005260:Female; D015658:HIV Infections / Q000097:blood / Q000150:complications* / Q000453:epidemiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D016036:Seroepidemiologic Studies
D000913:Antibodies, Protozoan