title: Histoplasmosis-associated hemophagocytic syndrome: a case report.
abstract: Hemophagocytic syndrome is a macrophage disorder that may develop as a result of immunological activation, such as that seen in severe infection. It has been described in persons with HIV/AIDS and in those with a variety of HIV-associated opportunistic infections, including those caused by Histoplasma capsulatum. If present, this disorder may portend a poorer prognosis. We describe an HIV-positive person in whom histoplasmosis-associated hemophagocytic syndrome was successfully treated.
authors.affiliation: Department of Infectious Diseases, Keck School of Medicine, University of Southern California, Los Angeles, USA.
authors.forename: Alejandro
authors.initials: A
authors.lastname: Sanchez
authors.forename: Anna K
authors.initials: AK
authors.lastname: Celaya
authors.forename: Anthony
authors.initials: A
authors.lastname: Victorio
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000276:immunology / Q000382:microbiology; D015658:HIV Infections / Q000276:immunology / Q000382:microbiology*; D006658:Histoplasma; D006660:Histoplasmosis / Q000188:drug therapy / Q000276:immunology* / Q000821:virology; D006801:Humans; D051359:Lymphohistiocytosis, Hemophagocytic / Q000188:drug therapy / Q000276:immunology / Q000382:microbiology*; D008297:Male; D008875:Middle Aged; D014376:Tuberculosis / Q000188:drug therapy / Q000276:immunology / Q000382:microbiology