title: Adamantiades-Behcet disease: diagnosis and current concepts in management of ocular manifestations.
abstract: Adamantiades-Behcet disease is a relapsing systemic vasculitis that may involve the eyes, skin, and almost all other organ systems. The comprehensive ophthalmologist plays a key role by not only making the diagnosis but also by monitoring inflammatory status to guide systemic therapy. If left untreated, the disease has a high likelihood of causing blindness and death. Adamantiades-Behcet disease with retinal involvement is now considered an absolute indication for systemic immunomodulatory therapy. The diagnostic signs, potential complications, and treatment modalities currently available for ocular Adamantiades-Behcet disease are reviewed.
authors.affiliation: Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA, USA.
authors.forename: Khayyam
authors.initials: K
authors.lastname: Durrani
authors.forename: Muna
authors.initials: M
authors.lastname: Ahmed
authors.forename: C Stephen
authors.initials: CS
authors.lastname: Foster
mesh_terms: D001528:Behcet Syndrome / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy; D003937:Diagnosis, Differential; D005451:Fluorescein Angiography; D005654:Fundus Oculi; D006801:Humans; D007155:Immunologic Factors / Q000627:therapeutic use*; D011379:Prognosis; D031300:Retinal Vasculitis / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology; D014792:Visual Acuity
chemical_list: D007155:Immunologic Factors