Supracricoid partial laryngectomies after radiation failure: a multi-institutional series.
BACKGROUND
Radiation therapy (RT) is one of the gold standard treatments for early laryngeal cancer, and total laryngectomy is still the most applied surgical procedure after failure. Selected recurrences can be managed by supracricoid partial laryngectomies (SCPLs).


METHODS
A multi-institutional retrospective analysis was carried out in 78 consecutive patients treated by SCPLs for the recurrence of glottic-supraglottic cancer after RT. Cricohyoidoepiglottopexy was performed in 62, and cricohyoidopexy (CHP) in 16 cases.


RESULTS
Disease-free survival at 3 and 5 years were 95.5%. Early and late postoperative complications occurred in 27% and 17.9% of cases. Decannulation and satisfactory swallowing were achieved in 97.4% of cases.


CONCLUSIONS
SCPLs represent effective surgical organ-preservation strategies in the treatment of selected recurrences after RT failure, resulting in a good local control as well as functional recovery with acceptable morbidity, despite a complication rate which is not negligible.
Pellini
Raul
R
Department of Otorhinolaryngology-Head and Neck Surgery, National Cancer Institute Regina Elena, Rome, Italy.
Pichi
Barbara
B
Ruscito
Paolo
P
Ceroni
Alberto Rinaldi
AR
Caliceti
Umberto
U
Rizzotto
Giuseppe
G
Pazzaia
Antonio
A
Laudadio
Pasquale
P
Piazza
Cesare
C
Peretti
Giorgio
G
Giannarelli
Diana
D
Spriano
Giuseppe
G
D000328:Adult; D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000401:mortality / Q000532:radiotherapy / Q000601:surgery*; D006801:Humans; D007822:Laryngeal Neoplasms / Q000401:mortality / Q000532:radiotherapy / Q000601:surgery*; D007825:Laryngectomy / Q000379:methods*; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D037981:Neck Dissection; D009364:Neoplasm Recurrence, Local / Q000601:surgery*; D011183:Postoperative Complications; D012189:Retrospective Studies; D013957:Thyroid Cartilage / Q000601:surgery; D017211:Treatment Failure; D014833:Voice Quality