title: [Conjunctival melanoma at corneoscleral limbus on primary acquired melanosis. A case report].
abstract: A 51-year-old Caucasian man consulted for a visual loss in the left eye due to corneal extension of a conjunctival melanoma. This conjunctival melanoma arose from primary acquired melanosis with atypia at the temporal corneoscleral limbus. The patient was treated using a combination of surgical excision with physical treatment by ocular proton therapy. Progression remained under control 11 months after treatment: no local tumour recurrence or metastasis was observed. Primary acquired melanosis with atypia must be regarded as a premalignant melanocytic lesion. Based on this case report, the authors focus on primary acquired melanosis and its risk of transformation to a conjunctival malignant melanoma.
authors.affiliation: Service d'Ophtalmologie, Hôpital d'Instruction des Armées Laveran, Marseille, France. elodiechazalon@yahoo.fr
authors.forename: E
authors.initials: E
authors.lastname: Chazalon-Pauleau
authors.forename: L
authors.initials: L
authors.lastname: Roux
authors.forename: J-H
authors.initials: JH
authors.lastname: Patte
authors.forename: S
authors.initials: S
authors.lastname: Pommier
authors.forename: D
authors.initials: D
authors.lastname: Bonnet
authors.forename: F
authors.initials: F
authors.lastname: Meyer
mesh_terms: D003230:Conjunctival Neoplasms / Q000473:pathology* / Q000601:surgery; D018450:Disease Progression; D006801:Humans; D016850:Limbus Corneae / Q000473:pathology*; D008297:Male; D008545:Melanoma / Q000473:pathology* / Q000601:surgery; D008875:Middle Aged; D011230:Precancerous Conditions / Q000473:pathology; D016896:Treatment Outcome