title: Demographic risk factors for severe and fatal vivax and falciparum malaria among hospital admissions in northeastern Indonesian Papua.
abstract: Between January 1998 and December 2000, the Jayapura Provincial Public Hospital in northeastern Indonesian New Guinea (Papua) admitted 5,936 patients with a diagnosis of malaria. The microscopic diagnosis at admission was Plasmodium falciparum (3,976, 67%), Plasmodium vivax (1,135, 19%), Plasmodium malariae (8, < 1%), and mixed species infections (817, 14%). Approximately 9% (367) of patients were classified as having severe malaria (277 P. falciparum, 36 P. vivax, 53 mixed infections, and 1 P. malariae) and 88 died (79 P. falciparum/mixed infections and 9 P. vivax). Risk of fatal outcomes among severe malaria patients was indistinguishable between those with falciparum versus vivax malaria (OR = 0.89; P = 0.771). Compared with non-pregnant women, pregnant women showed no higher risk of severe malaria (P = 0.643) or death caused by severe malaria (P = 0.748). This study compares admissions per population (based on census data), parasitemia, morbidity, and mortality among children versus adults, pregnant versus non-pregnant women, and urban/suburban versus rural residents.
authors.affiliation: US Naval Medical Research Unit #2, Jakarta, Indonesia. mazie_barcus@yahoo.com
authors.forename: Mazie J
authors.initials: MJ
authors.lastname: Barcus
authors.forename: Hasan
authors.initials: H
authors.lastname: Basri
authors.forename: Helena
authors.initials: H
authors.lastname: Picarima
authors.forename: C
authors.initials: C
authors.lastname: Manyakori
authors.lastname: Sekartuti
authors.forename: Iqbal
authors.initials: I
authors.lastname: Elyazar
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Bangs
authors.forename: Jason D
authors.initials: JD
authors.lastname: Maguire
authors.forename: J Kevin
authors.initials: JK
authors.lastname: Baird
mesh_terms: D000293:Adolescent; D017677:Age Distribution; D002648:Child; D002675:Child, Preschool; D006760:Hospitalization; D006801:Humans; D007214:Indonesia; D007223:Infant; D007231:Infant, Newborn; D016778:Malaria, Falciparum / Q000453:epidemiology* / Q000401:mortality; D016780:Malaria, Vivax / Q000453:epidemiology* / Q000401:mortality; D012189:Retrospective Studies; D012307:Risk Factors