Malignant fibrous histiocytoma arising in the area of total hip replacement.
A patient developed a rapidly progressive and extensive periprosthetic osteolysis after a cemented total hip arthroplasty for postradiation necrosis of pelvic bone and femoral head. Malignant tumor is one of the causes of periprosthetic bone loss. The biopsy confirmed the malignant fibrous histiocytoma (MFH). However, majority of periprosthetic bone loss is due to wear debris induced osteolysis. Usually, wear debris induced periprosthetic osteolysis is developed later and the progression is much slower than there of malignant tumor. Also wear debris induced osteolysis is confirmed by chronic inflammation with macrophages containing wear particles. When there is a rapidly progressive and extensive osteolysis a prosthesis following hip replacement arthroplasty, the physician should suspect the possibility of malignant tumor.
Min
Woo-Kie
WK
Department of Orthopedic Surgery, College of Medicine, Kyungpook National University, Samduck 2 Ga 50, Jung-Gu, Daegu 700-721, South Korea.
Kim
Shin-Yoon
SY
Oh
Chang-Wug
CW
Kim
Sung-Jung
SJ
Park
Tae-In
TI
Koo
Kyung-Hoi
KH
D000058:Accidental Falls; D019644:Arthroplasty, Replacement, Hip / Q000009:adverse effects*; D005260:Female; D005271:Femur Head Necrosis / Q000209:etiology / Q000601:surgery*; D006620:Hip Fractures / Q000209:etiology; D051677:Histiocytoma, Malignant Fibrous / Q000209:etiology*; D006801:Humans; D008875:Middle Aged; D010014:Osteolysis / Q000209:etiology; D010025:Osteoradionecrosis / Q000209:etiology; D010384:Pelvic Bones / Q000473:pathology / Q000601:surgery; D011878:Radiotherapy / Q000009:adverse effects; D002583:Uterine Cervical Neoplasms / Q000532:radiotherapy