[Fetal bladder development. A current overview].
Human fetal bladder development starts in the 9th to 10th week of gestation. Smooth muscle cell formation is induced by Hedgehog proteins and their signaling in the surrounding mesenchyma of the fetal bladder cavity. Bladder wall thickness increases significantly with advancing gestation, mediated by linear growth patterns irrespective of the related sex. lt is the aim of this article to address new insights into bladder development to enhance our knowledge about normal and pathological conditions that occur when developmental processes are disturbed.
Körner
I
I
European Academy of Pediatric Urology, Abteilung für Kinderurologie der Universität Regensburg, Klinik St. Hedwig, Steinmetzstrasse 1-3, Regensburg, Germany. iris.koerner@barmherzige-regensburg.de
D000199:Actins / Q000032:analysis; D000818:Animals; D005260:Female; D005865:Gestational Age; D053823:Hedgehog Proteins / Q000032:analysis; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D051379:Mice; D009130:Muscle, Smooth / Q000196:embryology / Q000473:pathology; D011247:Pregnancy; D011467:Prostate / Q000196:embryology / Q000473:pathology; D012733:Sex Differentiation; D015398:Signal Transduction / Q000502:physiology; D016216:Ultrasonography, Prenatal; D001743:Urinary Bladder / Q000196:embryology* / Q000473:pathology; D014564:Urogenital Abnormalities / Q000196:embryology / Q000473:pathology; D014621:Vagina / Q000196:embryology / Q000473:pathology
D000199:Actins; D053823:Hedgehog Proteins; C509239:SHH protein, human