title: Verbal memory, negative symptomatology and prediction of psychosocial functioning in schizophrenia.
abstract: Negative symptomatology and neurocognitive variables have been considered good predictors of functional outcome in schizophrenia. Specifically, secondary verbal memory has been proposed to be one of the main predictors of psychosocial functioning. In this study, negative symptoms and memory performance were analyzed for associations with psychosocial function. Linear regression methods were used to analyze the value of verbal memory and negative symptomatology as predictors of everyday life skills in a sample of 29 DSM-IV schizophrenia outpatients with predominant negative symptoms. We also took into account the role of gender in the analyses. Secondary verbal memory was found to explain 40% of the variance in psychosocial functioning, independently of gender, whereas the negative symptoms predicted 26%. When both variables were combined, the explained variance was about 49%. These results support the hypothesis that cognitive variables are better predictors than symptomatology. Finally, secondary verbal memory is a good predictor of psychosocial functioning in chronic schizophrenia with predominant negative symptomatology.
authors.affiliation: Neurosciencies Institute, Hospital Universtari Clínic, Barcelona, Spain.
authors.forename: Olga
authors.initials: O
authors.lastname: Puig
authors.forename: Rafael
authors.initials: R
authors.lastname: Penadés
authors.forename: Cristobal
authors.initials: C
authors.lastname: Gastó
authors.forename: Rosa
authors.initials: R
authors.lastname: Catalán
authors.forename: Anna
authors.initials: A
authors.lastname: Torres
authors.forename: Manel
authors.initials: M
authors.lastname: Salamero
mesh_terms: D000328:Adult; D000339:Affect; D002908:Chronic Disease; D003072:Cognition Disorders / Q000175:diagnosis / Q000453:epidemiology; D039721:Diagnostic and Statistical Manual of Mental Disorders; D005260:Female; D006801:Humans; D007360:Intelligence; D008297:Male; D008569:Memory Disorders / Q000175:diagnosis / Q000453:epidemiology*; D009483:Neuropsychological Tests; D011237:Predictive Value of Tests; D015995:Prevalence; D011584:Psychology; D012559:Schizophrenia / Q000175:diagnosis / Q000453:epidemiology*; D012720:Severity of Illness Index; D014705:Verbal Behavior; D014888:Wechsler Scales