title: Efficacy of permethrin cream and oral ivermectin in treatment of scabies.
abstract: OBJECTIVE
  To compare the efficacy of mass treatment of scabies with permethrin cream and oral ivermectin in a closed urban pediatric population.
  
  
  METHODS
  A comparative trial of topical permethrin and oral ivermectin was conducted in a closed population of 84 children living in a urban hostel of Delhi.
  
  
  RESULTS
  After mass treatment with 2 doses of oral ivermectin, one case was recorded in following 6 months, as compared to 22 cases in preceding 6 months when children were treated with a single application of 5% permethrin.
  
  
  CONCLUSIONS
  Mass treatment of scabies with ivermectin in an endemic population is more efficacious as compared to topical permethrin application in reducing the baseline prevalence, decreasing the chain of transmission and chances of reinfection.
authors.affiliation: Department of Pediatrics, Rajiv Gandhi Cancer Institute, Delhi, India.
authors.forename: Sarfrazul
authors.initials: S
authors.lastname: Abedin
authors.forename: Manish
authors.initials: M
authors.lastname: Narang
authors.forename: Vijay
authors.initials: V
authors.lastname: Gandhi
authors.forename: Shiva
authors.initials: S
authors.lastname: Narang
mesh_terms: D000279:Administration, Cutaneous; D000284:Administration, Oral; D000293:Adolescent; D000977:Antiparasitic Agents / Q000008:administration & dosage*; D002648:Child; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D019353:Endemic Diseases; D006801:Humans; D007194:India; D007306:Insecticides / Q000008:administration & dosage*; D007559:Ivermectin / Q000008:administration & dosage*; D008297:Male; D026023:Permethrin / Q000008:administration & dosage*; D012532:Scabies / Q000188:drug therapy*; D012574:Schools; D055502:Secondary Prevention; D016896:Treatment Outcome; D014505:Urban Population
chemical_list: D000977:Antiparasitic Agents; D007306:Insecticides; D026023:Permethrin; D007559:Ivermectin