Successful conservative management of hereditary hemorrhagic telangiectasia in pregnancy. A case report.
BACKGROUND
Hereditary hemorrhagic telangiectasia (HHT) is a condition characterized by multiple telangiectases and arteriovenous malformations. Women with HHT may develop life-threatening complications in pregnancy. In particular, death from pulmonary hemorrhage has been reported. Consequently, these women are often advised not to conceive or to terminate their pregnancies.


METHODS
We report a case of conservative management of HHT in pregnancy with a good outcome.


CONCLUSIONS
This case demonstrates that in carefully selected cases, women with HHT who are managed conservatively may have good pregnancy outcomes. A diagnosis of HHT alone is not reason to advise women against pregnancy, nor should these women routinely be advised to undergo pregnancy termination.
Schwebel
Marlene
M
Division of Maternal-Fetal Medicine, Department of Obstetrics, Gynecology, and Reproductive Sciences, UMDNJ-Robert Wood Johnson Medical School, New Brunswick, NJ 08901-1977, USA.
Oyelese
Yinka
Y
Nath
Carl
C
Ashkinadze
Elena
E
Vintzileos
Anthony M
AM
Smulian
John C
JC
D000328:Adult; D001165:Arteriovenous Malformations / Q000150:complications* / Q000235:genetics; D001784:Blood Gas Analysis; D005260:Female; D005817:Genetic Counseling; D006801:Humans; D007231:Infant, Newborn; D011247:Pregnancy; D011248:Pregnancy Complications / Q000235:genetics / Q000628:therapy*; D011256:Pregnancy Outcome; D013683:Telangiectasia, Hereditary Hemorrhagic / Q000235:genetics / Q000628:therapy*