Catalytic enantioselective addition of arylboronic acids to N-boc imines generated in situ.
The rhodium-catalyzed addition of arylboronic acids to N-Boc imines generated in situ from stable and easily prepared alpha-carbamoyl sulfones has been developed. High enantioselectivities are observed for additions of arylboronic acids with a variety of steric and electronic properties.
Nakagawa
Hiroshi
H
Department of Chemistry, University of California, Berkeley, California 94720-1460, USA.
Rech
Jason C
JC
Sindelar
Robert W
RW
Ellman
Jonathan A
JA
D001897:Boronic Acids / Q000737:chemistry*; D002384:Catalysis; D007097:Imines / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D013237:Stereoisomerism
D001897:Boronic Acids; D007097:Imines