Risk-based health monitoring of childhood cancer survivors: a report from the Children's Oncology Group.
Because of therapeutic advances over the past 50 years, long-term survival is now a reality for nearly 80% of children and adolescents diagnosed with cancer. The growing population of childhood cancer survivors is notable for its vulnerability to adverse health outcomes, many of which may not become clinically apparent until years after therapy completion. Early detection, prevention, and ameliorative interventions provide the opportunity to reduce cancer-related morbidity and mortality. This review is intended to complement the Children's Oncology Group Long-Term Follow-Up Guidelines for Survivors of Childhood, Adolescent, and Young Adult Cancers. The objective of this review is to familiarize readers with the diverse health risks experienced by childhood cancer survivors that stem from the heterogeneous therapeutic interventions required to achieve disease control.
Nunez
Susan B
SB
Department of Oncology, Division of Cancer Survivorship, University of Tennessee College of Medicine, St. Jude Children's Research Hospital, 332 North Lauderdale Street, Mailstop 735, Memphis, TN 38119, USA.
Mulrooney
Daniel A
DA
Laverdiere
Caroline
C
Hudson
Melissa M
MM
D000293:Adolescent; D000328:Adult; D000970:Antineoplastic Agents / Q000009:adverse effects; D002648:Child; D005500:Follow-Up Studies; D006305:Health Status Indicators; D006801:Humans; D009369:Neoplasms / Q000150:complications* / Q000628:therapy; D017410:Practice Guidelines as Topic; D011788:Quality of Life; D011878:Radiotherapy / Q000009:adverse effects; D017741:Survivors
D000970:Antineoplastic Agents