title: Multivitamin and dietary supplements, body weight and appetite: results from a cross-sectional and a randomised double-blind placebo-controlled study.
abstract: Two studies were conducted to compare characteristics of consumers and non-consumers of vitamin and/or dietary supplements (study 1) and to assess the effect of a multivitamin and mineral supplementation during a weight-reducing programme (study 2). Body weight and composition, energy expenditure, and Three-Factor Eating Questionnaire scores were compared between consumers and non-consumers of micronutrients and/or dietary supplements in the Québec Family Study (study 1). In study 2, these variables and appetite ratings (visual analogue scales) were measured in forty-five obese non-consumers of supplements randomly assigned to a double-blind 15-week energy restriction ( - 2930 kJ/d) combined with a placebo or with a multivitamin and mineral supplement. Compared with non-consumers, male consumers of vitamin and/or dietary supplements had a lower body weight (P < 0.01), fat mass (P < 0.05), BMI (P < 0.05), and a tendency for greater resting energy expenditure (P = 0.06). In women, the same differences were observed but not to a statistically significant extent. In addition, female supplements consumers had lower disinhibition and hunger scores (P < 0.05). In study 2, body weight was significantly decreased after the weight-loss intervention (P < 0.001) with no difference between treatment groups. However, fasting and postprandial appetite ratings were significantly reduced in multivitamin and mineral-supplemented women (P < 0.05). Usual vitamin and/or dietary supplements consumption and multivitamin and mineral supplementation during a weight-reducing programme seems to have an appetite-related effect in women. However, lower body weight and fat were more detectable in male than in female vitamin and/or dietary supplements consumers.
authors.affiliation: Division of Kinesiology, Department of Social and Preventive Medicine, Laval University, Québec, Canada.
authors.forename: Geneviève C
authors.initials: GC
authors.lastname: Major
authors.forename: Eric
authors.initials: E
authors.lastname: Doucet
authors.forename: Mélanie
authors.initials: M
authors.lastname: Jacqmain
authors.forename: Myriam
authors.initials: M
authors.lastname: St-Onge
authors.forename: Claude
authors.initials: C
authors.lastname: Bouchard
authors.forename: Angelo
authors.initials: A
authors.lastname: Tremblay
mesh_terms: D000328:Adult; D000886:Anthropometry; D001066:Appetite / Q000187:drug effects*; D001823:Body Composition / Q000187:drug effects; D001835:Body Weight / Q000187:drug effects*; D003430:Cross-Sectional Studies; D015930:Diet Records; D004038:Diet, Reducing; D019587:Dietary Supplements; D004311:Double-Blind Method; D002149:Energy Intake / Q000187:drug effects; D004734:Energy Metabolism / Q000187:drug effects; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000178:diet therapy* / Q000503:physiopathology; D014815:Vitamins / Q000494:pharmacology*; D015431:Weight Loss / Q000187:drug effects; D055815:Young Adult
chemical_list: D014815:Vitamins