title: The changes in the energy metabolism of human muscle induced by training.
abstract: The biochemical effects of training programmes have been studied with a kinetic model of central metabolism, using enzyme activities and metabolite concentrations measured at rest and after 30 s maximum-intensity exercise, collected before and after long and short periods of training, which differed only by the duration of the rest intervals. After short periods of training the glycolytic flux at rest was three times higher than it had been before training, whereas during exercise the flux and energy consumption remained the same as before training. Long periods of training had less effect on the glycolytic flux at rest, but increased it in response to exercise, increasing the contribution of oxidative phosphorylation.
authors.affiliation: Department of Biochemistry and Molecular Biology, Faculty of Biology, Associated Unit to CSIC, Institute of Biomedicine of University of Barcelona and CeRQT at Barcelona Scientific Park, Diagonal 645, 08028 Barcelona, Spain.
authors.forename: V A
authors.initials: VA
authors.lastname: Selivanov
authors.forename: P
authors.initials: P
authors.lastname: de Atauri
authors.forename: J J
authors.initials: JJ
authors.lastname: Centelles
authors.forename: J
authors.initials: J
authors.lastname: Cadefau
authors.forename: J
authors.initials: J
authors.lastname: Parra
authors.forename: R
authors.initials: R
authors.lastname: Cussó
authors.forename: J
authors.initials: J
authors.lastname: Carreras
authors.forename: M
authors.initials: M
authors.lastname: Cascante
mesh_terms: D000465:Algorithms; D004734:Energy Metabolism / Q000502:physiology*; D015444:Exercise / Q000502:physiology*; D006019:Glycolysis / Q000502:physiology; D006801:Humans; D008954:Models, Biological; D018482:Muscle, Skeletal / Q000378:metabolism* / Q000502:physiology; D013997:Time Factors