title: [Nocturia in obstructive sleep apnoea (OSA)].
abstract: BACKGROUND
  Nocturia (two or more urinations per night) is a common symptom in OSA subjects. Higher secretion of atrial natriuretic peptide, increased intra-abdominal pressure, diuretics, diabetes, excessive fluid intake, awakenings are responsible for nocturnal urination. The aim of this study was to evaluate incidence of nocturia in moderate and severe OSA.
  
  
  METHODS
  We studied 171 consecutive OSA patients (135 males and 36 females) - means: age - 53.6 +/- +/- 10.8 years, AHI/RDI - 43.6 +/- 23.2, BMI - 35.8 +/- 6.3 kg/m(2).
  
  
  RESULTS
  To assess relations between nocturia and AHI/RDI, overnight saturation, BMI and daytime sleepiness we divided subjects in two groups: 1(st) - without nocturia - 60 pts; 35.1% (group N-) and 2(nd) - with nocturia - 111 pts; 64.9% (group N+). Group N+ presented with higher AHI/RDI, 48 +/- 22.8 vs. 35.4 +/- 21.7 (p = 0.0006), higher BMI, 36.8 +/- 6.5 vs. 34 +/- 5.5 kg/m(2) (p = 0.004), lower mean overnight SaO(2), 88.6 +/- 5.6 vs. 90.4 +/- 4.3% (p = 0.03) and daytime sleepiness, Epworth score - 14.4 +/- 5.1 vs. 11.3 +/- 5.5 points (p = 0.0002). Multiple linear regression analysis revealed significant correlation between nocturia and Epworth sleepiness score (beta = 0.26, p = 0.0009), coronary artery disease (beta = 0.23, p = 0.004) and AHI/RDI (beta = 0.21, p = 0.04).
  
  
  CONCLUSIONS
  Nocturia is frequent in OSA patients (64.9%). Nocturnal urination was related to severity of OSA, excessive daytime sleepiness and coronary artery disease.
authors.affiliation: Zakład Diagnostyki i Leczenia Niewydolności Oddychania Instytutu Gruzlicy i Chorób Płuc w Warszawie.
authors.forename: Robert
authors.initials: R
authors.lastname: Pływaczewski
authors.forename: Anna
authors.initials: A
authors.lastname: Stokłosa
authors.forename: Michał
authors.initials: M
authors.lastname: Bednarek
authors.forename: Justyna
authors.initials: J
authors.lastname: Czerniawska
authors.forename: Przemysław
authors.initials: P
authors.lastname: Bieleń
authors.forename: Dorota
authors.initials: D
authors.lastname: Górecka
authors.forename: Paweł
authors.initials: P
authors.lastname: Sliwiński
mesh_terms: D000328:Adult; D000368:Aged; D015992:Body Mass Index; D015897:Comorbidity; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D053158:Nocturia / Q000453:epidemiology* / Q000209:etiology; D011044:Poland / Q000453:epidemiology; D017286:Polysomnography; D012720:Severity of Illness Index; D020181:Sleep Apnea, Obstructive / Q000150:complications* / Q000175:diagnosis