title: Pharmacotherapy of cough-variant asthma.
abstract: Cough-variant asthma is considered as an asthma subset in which chronic cough is the only symptom. It is believed to be more frequent and, hence, sometimes overdiagnosed in children, and shares with typical asthma eosinophilic airway inflammation and consequent bronchial hyper-responsiveness. Presently available therapies consist of bronchodilators, inhaled or oral corticosteroids, or leukotriene modifiers. However, the long-term efficacy of these agents in adults and children is not known. This review focuses on current therapies used for cough variant asthma, also highlighting potential therapeutic targets for this condition.
authors.affiliation: University of Medicine and Pharmacy, Gr.T.Popa Iasi, Pulmonary Disease Division, 30 Dr I Cihac Str, 700115 Iasi, Romania. saantoniu@pneumo.umfiasi.ro
authors.forename: Sabina A
authors.initials: SA
authors.lastname: Antoniu
authors.forename: T
authors.initials: T
authors.lastname: Mihaescu
authors.forename: Claudio F
authors.initials: CF
authors.lastname: Donner
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D018927:Anti-Asthmatic Agents / Q000627:therapeutic use*; D001249:Asthma / Q000145:classification / Q000150:complications / Q000188:drug therapy* / Q000473:pathology / Q000503:physiopathology; D016535:Bronchial Hyperreactivity / Q000188:drug therapy; D001993:Bronchodilator Agents / Q000627:therapeutic use; D003371:Cough / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology / Q000503:physiopathology; D004804:Eosinophils / Q000473:pathology; D006801:Humans; D020024:Leukotriene Antagonists / Q000627:therapeutic use; D016896:Treatment Outcome
chemical_list: D000305:Adrenal Cortex Hormones; D018927:Anti-Asthmatic Agents; D001993:Bronchodilator Agents; D020024:Leukotriene Antagonists