Sensitive, selective, and irreversible inhibition of cyclooxygenase-2 activity by copper.
Nagano
Seiichi
S
Laboratory for Oxidation Biology, Genetics and Aging Research Unit and Department of Psychiatry, Harvard Medical School, Massachusetts General Hospital East, Bldg 114 16th Street, Charlestown, MA 02129, USA.
Bush
Ashley I
AI
D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000494:pharmacology*; D001665:Binding Sites; D001792:Blood Platelets / Q000201:enzymology; D003300:Copper / Q000494:pharmacology*; D051546:Cyclooxygenase 2 / Q000378:metabolism*; D052246:Cyclooxygenase 2 Inhibitors / Q000494:pharmacology*; D006801:Humans; D007213:Indomethacin / Q000494:pharmacology; D018836:Inflammation Mediators / Q000494:pharmacology; D011453:Prostaglandins / Q000378:metabolism; D012680:Sensitivity and Specificity
D000894:Anti-Inflammatory Agents, Non-Steroidal; D052246:Cyclooxygenase 2 Inhibitors; D018836:Inflammation Mediators; D011453:Prostaglandins; D003300:Copper; D051546:Cyclooxygenase 2; D007213:Indomethacin