Ventilator-induced lung injury and mechanotransduction: why should we care?
Mechanotransduction holds the underlying mechanisms of ventilator-induced lung injury. Research on this subject, however, could be difficult for clinicians, especially when results are controversial. A recent study by Li and co-workers is used as an example, to explain how to critically read literatures related to basic science and how to understand the limitation of experimental studies.
Liu
Mingyao
M
D000818:Animals; D016207:Cytokines / Q000378:metabolism; D004195:Disease Models, Animal; D018496:Hyperoxia / Q000209:etiology / Q000378:metabolism; D008168:Lung / Q000201:enzymology*; D020556:Neutrophil Infiltration; D052250:Nitric Oxide Synthase Type III / Q000378:metabolism*; D017346:Protein Serine-Threonine Kinases / Q000378:metabolism*; D012121:Respiration, Artificial / Q000009:adverse effects*
D016207:Cytokines; D052250:Nitric Oxide Synthase Type III; D017346:Protein Serine-Threonine Kinases