title: Hypoglycemia in a patient with a huge malignant solitary fibrous tumor of the pleura.
abstract: Solitary fibrous tumor of the pleura (SFTP) is rare. A 73-year-old man, without past history of diabetes mellitus, was admitted to hospital with profound hypoglycemia, loss of consciousness and respiratory failure. CT indicated a huge heterogenous mass lesion (12 x 12 x 17 cm) at the right thoracic cavity with total atelectasis of the right lower lung. He underwent a standard thoracotomy with complete excision of the tumor. Pathology indicated malignant SFTP with insulin-like growth factor-binding protein-2 production. There were no further incidences of hypoglycemia or respiratory failure after excision of the tumor. Hypoglycemia resulting from a solitary fibrous tumor is uncommon. Standard thoracotomy and complete resection of this giant tumor provided a good result for the present patient.
authors.affiliation: Division of Thoracic and Cardiovascular Surgery, Buddhist Tzu Chi General Hospital, Hualien, Taiwan. med.ray@msa.hinet.net
authors.forename: Jui-Chih
authors.initials: JC
authors.lastname: Chang
authors.forename: Kuei-Ying
authors.initials: KY
authors.lastname: Su
authors.forename: Shen-Feng
authors.initials: SF
authors.lastname: Chao
authors.forename: Yung-Hsiang
authors.initials: YH
authors.lastname: Hsu
authors.forename: Gee-Gwo
authors.initials: GG
authors.lastname: Yang
authors.forename: Bee-Song
authors.initials: BS
authors.lastname: Chang
mesh_terms: D000368:Aged; D006801:Humans; D007003:Hypoglycemia / Q000209:etiology*; D007150:Immunohistochemistry; D007335:Insulin-Like Growth Factor II / Q000378:metabolism*; D008297:Male; D010997:Pleural Neoplasms / Q000150:complications* / Q000378:metabolism / Q000473:pathology*; D054364:Solitary Fibrous Tumors / Q000150:complications* / Q000378:metabolism / Q000473:pathology*; D019616:Thoracic Surgical Procedures
chemical_list: C035170:IGF2 protein, human; D007335:Insulin-Like Growth Factor II