title: Exercise responses in boys with attention deficit/hyperactivity disorder: effects of stimulant medication.
abstract: OBJECTIVE
  The effect of stimulant medication on exercise responses was studied in 14 boys (10.9 +/- 1.1 years) with attention deficit/hyperactivity disorder (ADHD).
  
  
  METHODS
  Exercise, with and without medication, was performed at 25 W, 50 W, and 75 W, followed by a peak exercise test.
  
  
  RESULTS
  Submaximal heart rate (HR) was significantly higher by ~8 to 13 b.min(-1) across the three intensities during the medication trial, but oxygen uptake (VO(2)), respiratory exchange ratio (RER), and perceived exertion were similar (p > .05). At peak exercise, VO(2), HR, and work rate were attenuated (p < or = .05) in the absence of medication but not RER or perceived exertion. The decreased peak exercise responses were apparent in 6 of 13 participants.
  
  
  CONCLUSIONS
  Stimulant medication raises submaximal HR but does not affect other cardiorespiratory measures or perceived exertion. Without medication physiological responses at peak exercise are attenuated in some but not all boys with ADHD.
authors.affiliation: Human Performance Laboratory, Ball State University, Muncie, Indiana 47306, USA. tmahon@bsu.edu
authors.forename: Anthony D
authors.initials: AD
authors.lastname: Mahon
authors.forename: Brooke R
authors.initials: BR
authors.lastname: Stephens
authors.forename: Andrew S
authors.initials: AS
authors.lastname: Cole
mesh_terms: D001289:Attention Deficit Disorder with Hyperactivity / Q000175:diagnosis / Q000188:drug therapy*; D000697:Central Nervous System Stimulants / Q000627:therapeutic use*; D002648:Child; D015444:Exercise; D006339:Heart Rate / Q000502:physiology*; D006801:Humans; D008297:Male; D008774:Methylphenidate / Q000627:therapeutic use*; D012720:Severity of Illness Index; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D000697:Central Nervous System Stimulants; D008774:Methylphenidate