[Bronchial reactivity in chronic obstructive bronchitis].
The frequency and the degree of bronchial hyperreactivity was investigated in 92 patients suffering from chronic obstructive bronchitis. Bronchial reactivity was examgned by the inhalator acetylcholine test, with the use of a 5 mg dose of acetylcholine, diluted in 1 ml of sodium-chloride solution. The pulmonary function was estimated upon the results of parameters received by forced expiration and body plethysmography. The results have shown the obvious bronchial hyperreactivity in 42 percent of all patients suffering from chronic obstructive bronchitis. The average quantity of acetylcholine, which is supficient to provoke a bronchial reaction, is 3 mg, with a moderate bronchoconstrictory response, localized mostly in the large airways. The author concludes that the inhalator provocative test by cholinergic agent solution may safely be applied in patients suffering from chornic obstructive bronchitis.
Drecun
V
V
D000328:Adult; D000368:Aged; D016535:Bronchial Hyperreactivity; D001985:Bronchial Provocation Tests; D029481:Bronchitis, Chronic / Q000503:physiopathology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged