Automated cell apoptosis characterization using active contours.
Programmed cell death, also known as apoptosis, is of fundamental importance in many biological processes and also highly associated with serious diseases like cancer and HIV. The current paper presents an innovative method for apoptosis phenomenon characterization based on apoptotic cell quantification and detection using active contours (snakes). Evaluation results against manual counts have proved the high accuracy and efficiency of the developed method.
Doukas
Charalampos N
CN
Dep. of Information & Communication Systems Engineering, University of the Aegean, Samos, Greece. doukas@aegean.gr
Maglogiannis
Ilias
I
D000818:Animals; D017209:Apoptosis; D002478:Cells, Cultured; D015658:HIV Infections / Q000473:pathology*; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D018715:Microscopy, Video; D009369:Neoplasms / Q000473:pathology*; D012984:Software