title: Recurrent deep venous thrombosis during optimal anticoagulation and overt hyperthyroidism: a case report.
abstract: Recurrent deep venous thrombosis despite well conducted anticoagulant treatment is an uncommon, but possible, event. It has been hypothesized that overt hyperthyroidism may increase thromboembolic risk. We present the case of an elderly man with a recurrent episode of deep venous thrombosis during optimal oral vitamin K antagonist treatment, associated with a new diagnosis of overt hyperthyroidism, with no evidence of occult cancer and normal levels of antiphosholipid antibodies.
authors.affiliation: Department of Clinical Medicine, University of Insubria, Varese, Italy. alexsquizzo@libero.it
authors.forename: Alessandro
authors.initials: A
authors.lastname: Squizzato
authors.forename: Josè
authors.initials: J
authors.lastname: Vitale
authors.forename: Victor Ea
authors.initials: VE
authors.lastname: Gerdes
authors.forename: Erica
authors.initials: E
authors.lastname: Romualdi
authors.forename: Harry R
authors.initials: HR
authors.lastname: Büller
authors.forename: Walter
authors.initials: W
authors.lastname: Ageno
mesh_terms: D000368:Aged; D000925:Anticoagulants / Q000627:therapeutic use*; D013956:Antithyroid Agents / Q000627:therapeutic use; D006801:Humans; D006980:Hyperthyroidism / Q000150:complications*; D008297:Male; D008713:Methimazole / Q000627:therapeutic use; D012008:Recurrence; D020246:Venous Thrombosis / Q000150:complications* / Q000188:drug therapy*; D014859:Warfarin / Q000627:therapeutic use*
chemical_list: D000925:Anticoagulants; D013956:Antithyroid Agents; D008713:Methimazole; D014859:Warfarin