title: Influence of overall and abdominal adiposity on C-reactive protein levels in elderly women.
abstract: OBJECTIVE
  To investigate how overall and abdominal adiposity, measured by waist circumference (WC), body mass index (BMI), and sum of skinfolds (sigmaSK), affect plasma C-reactive protein levels (CRP) in elderly women.
  
  
  METHODS
  Study sample consisted of 387 women older than 60 years (mean age 68.9; standard deviation 5.9 years). BMI, WC, sigmaSK, and CRP levels were all measured. One-way ANOVA was performed to detect differences in study variables among the CRP levels investigated. Logistic regression analysis was used to determine the influence of body fat measurements on CRP levels. The significance level was set at p < 0.05.
  
  
  RESULTS
  The analysis of variance showed that mean WC was lower in women with normal CRP levels, as compared to those with high CRP levels. Logistic regression analysis examined the influence of BMI, WC, and sigmaSK quartiles on CRP levels, yielding the following results: only WC was predictive of elevated CRP levels, its highest quartile (cut-off point of 94.0 cm) showing levels nearly two times higher than its lowest quartile (odds ratio = 2.23; 95% confidence interval = 1.92-4.18; p = 0.012).
  
  
  CONCLUSIONS
  The results of this study indicate that abdominal adiposity is a strong predictor of elevated CRP levels.
authors.affiliation: Universidade Federal do Paraná e Faculdade Evangélica do Paraná - Curitiba, PR - Brazil.
authors.forename: Jeffer Eidi
authors.initials: JE
authors.lastname: Sasaki
authors.forename: Maressa Priscila
authors.initials: MP
authors.lastname: Krause
authors.forename: Mirnaluci P R
authors.initials: MP
authors.lastname: Gama
authors.forename: Tatiane
authors.initials: T
authors.lastname: Hallage
authors.forename: Cosme Franklin
authors.initials: CF
authors.lastname: Buzzachera
authors.forename: Maria Gisele dos
authors.initials: MG
authors.lastname: Santos
authors.forename: Sergio Gregorio da
authors.initials: SG
authors.lastname: Silva
mesh_terms: D050153:Abdominal Fat / Q000473:pathology*; D050154:Adiposity; D000368:Aged; D000704:Analysis of Variance; D001172:Arthritis, Rheumatoid / Q000097:blood / Q000473:pathology; D015992:Body Mass Index; D002097:C-Reactive Protein / Q000032:analysis*; D003920:Diabetes Mellitus / Q000097:blood / Q000473:pathology; D005260:Female; D006801:Humans; D006973:Hypertension / Q000097:blood / Q000473:pathology; D016015:Logistic Models; D008875:Middle Aged; D009369:Neoplasms / Q000097:blood / Q000473:pathology; D016017:Odds Ratio; D012885:Skinfold Thickness; D052256:Tendinopathy / Q000097:blood / Q000473:pathology; D049629:Waist-Hip Ratio
chemical_list: D002097:C-Reactive Protein