title: Trajectories of cognitive decline and functional status in the frail older adults.
abstract: This study investigates the implications of different levels of cognitive decline on functional status in frail older adults. Four cognitive trajectories, including two with catastrophic cognitive decline, were defined in a 3-year study. Participants with complete cognitive and functional status data at baseline, 12 and 36 months of follow-up were included in the study (n=456). Data were analysed with repeated measures statistics. Substantial functional deterioration over time was observed for the participants with catastrophic cognitive decline. Catastrophic cognitive decline influenced performance in instrumental activities of daily living (IADL) and activities of daily living (ADL) at 12 months, whereas basic physical and mental actions were affected at 36 months. IADL were found to deteriorate more than ADL. The results have implications on planning appropriate geriatric rehabilitation and long-term care program.
authors.affiliation: Research Center, Montreal Geriatric University Institute, 4565 Queen Mary, Montreal, Quebec, H3W 1W5 Canada. rossitza.nikolova@umontreal.ca
authors.forename: Rossitza
authors.initials: R
authors.lastname: Nikolova
authors.forename: Louise
authors.initials: L
authors.lastname: Demers
authors.forename: François
authors.initials: F
authors.lastname: Béland
mesh_terms: D000203:Activities of Daily Living / Q000523:psychology*; D000368:Aged; D000369:Aged, 80 and over; D003071:Cognition / Q000502:physiology*; D003072:Cognition Disorders / Q000523:psychology* / Q000534:rehabilitation; D004185:Disability Evaluation; D018450:Disease Progression; D005260:Female; D005500:Follow-Up Studies; D016330:Frail Elderly / Q000523:psychology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis