Mammary fibroadenoma in a lamb.
A fibroadenoma was diagnosed in the left udder of a 3-month-old female Chios lamb. No recurrence was observed after surgery. Grossly, the tumor had a whitish-gray lobular appearance, and the lobules were interlaced with thin septa. Microscopically, the tumor was composed of proliferating fibroepithelial tissue, including differentiated ducts lined by whorls and interlacing bundles of abundant loose fibrovascular stroma. Immunohistochemistry revealed the ductal epithelium to be positive for pancytokeratin (AE1/AE3) and loose fibrovascular stroma was positive for vimentin and basal cells covering the ductal epithelium of alpha-smooth-muscle actin. Immunostaining for the estrogen and progesterone receptors was negative. A diagnosis of mammary fibroadenoma was made based on the histological and immunohistochemical findings.
Gulbahar
M Yavuz
MY
Department of Pathology, Faculty of Veterinary Medicine, University of Ondokuz Mayis, 55139 Kurupelit, Samsun, Turkey. mygulbahar@hotmail.com
Guvenc
Tolga
T
Yarim
Murat
M
Kabak
Yonca B
YB
Sozgen
Yuksel
Y
D000818:Animals; D005260:Female; D018226:Fibroadenoma / Q000473:pathology / Q000662:veterinary*; D007633:Keratins / Q000378:metabolism; D008321:Mammary Glands, Animal / Q000473:pathology*; D015674:Mammary Neoplasms, Animal / Q000473:pathology*; D012756:Sheep; D012757:Sheep Diseases / Q000473:pathology*; D014746:Vimentin / Q000378:metabolism
D014746:Vimentin; D007633:Keratins