title: Which cystography in the diagnosis and grading of vesicoureteral reflux?
abstract: The gold standard procedure for the evaluation of vesicoureteral reflux (VUR) is the radiographic voiding cystourethrography (VCUG); direct radionuclide voiding cystography (DRVC) is an alternative method for detecting VUR. A new imaging procedure, voiding urosonography (VUS) with contrast medium, has recently been introduced. We have carried out a comparative study of these three techniques in 157 patients (aged 6 weeks-4.7 years). VUS showed the presence of VUR in 91 of 311 renal units; VCUG detected reflux in 64 of 233 renal units, and the DRVC in 23 of 78 renal units. VCUG and VUS were compared in 118 patients, and both procedures showed the same grade of reflux in 56 refluxing units (kappa value 0.92); in six cases the reflux grade was greater at VUS than at VCUG. Seven cases of reflux detected by VUS were not identified on VCUG. VCUG did not show a grade of VUR that was higher than in VUS in any patient. In the identification of 4 degrees-5 degrees grade reflux, the sensitivity of VUS reached 100%. VUS and DRVC were found to be equally effective in the detection of VUR (kappa value 0.85). In conclusion, we found that VUS is a useful method for the diagnosis and grading of patients with VUR.
authors.affiliation: Department of Paediatrics, The Magna Graecia University of Catanzaro, Catanzaro, Italy.
authors.forename: Antonio
authors.initials: A
authors.lastname: Piscitelli
authors.forename: Rossella
authors.initials: R
authors.lastname: Galiano
authors.forename: Francesco
authors.initials: F
authors.lastname: Serrao
authors.forename: Daniela
authors.initials: D
authors.lastname: Concolino
authors.forename: Rosa
authors.initials: R
authors.lastname: Vitale
authors.forename: Giovanna
authors.initials: G
authors.lastname: D'Ambrosio
authors.forename: Vittoria
authors.initials: V
authors.lastname: Pascale
authors.forename: Pietro
authors.initials: P
authors.lastname: Strisciuglio
mesh_terms: D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D011877:Radionuclide Imaging; D014463:Ultrasonography; D014718:Vesico-Ureteral Reflux / Q000175:diagnosis* / Q000000981:diagnostic imaging