title: High power phased array prototype for clinical high intensity focused ultrasound : applications to transcostal and transcranial therapy.
abstract: Bursts of focused ultrasound energy three orders of magnitude more intense than diagnostic ultrasound became during the last decade a noninvasive option for treating cancer from breast to prostate or uterine fibroid. However, many challenges remain to be addressed. First, the corrections of distortions induced on the ultrasonic therapy beam during its propagation through defocusing obstacles like skull bone or ribs remain today a technological performance that still need to be validated clinically. Secondly, the problem of motion artifacts particularly important for the treatment of abdominal parts becomes today an important research topic. Finally, the problem of the treatment monitoring is a wide subject of interest in the growing HIFU community. For all these issues, the potential of new ultrasonic therapy devices able to work both in Transmit and Receive modes will be emphasized. A review of the work under achievement at L.O.A. using this new generation of HIFU prototypes on the monitoring, motion correction and aberrations corrections will be presented.
authors.affiliation: SuperSonic Imagine, 510 rue René Descartes 13857 Aix en Provence, France. mathieu.pernot@supersonicimagine.fr
authors.forename: M
authors.initials: M
authors.lastname: Pernot
authors.forename: J -F
authors.initials: J-
authors.lastname: Aubry
authors.forename: M
authors.initials: M
authors.lastname: Tanter
authors.forename: F
authors.initials: F
authors.lastname: Marquet
authors.forename: G
authors.initials: G
authors.lastname: Montaldo
authors.forename: A -L
authors.initials: A-
authors.lastname: Boch
authors.forename: M
authors.initials: M
authors.lastname: Kujas
authors.forename: D
authors.initials: D
authors.lastname: Seilhean
authors.forename: M
authors.initials: M
authors.lastname: Fink
mesh_terms: D000818:Animals; D001927:Brain Diseases / Q000628:therapy*; D007091:Image Processing, Computer-Assisted; D008171:Lung Diseases / Q000628:therapy*; D012272:Ribs; D012756:Sheep; D012886:Skull; D014057:Tomography, X-Ray Computed; D014464:Ultrasonic Therapy / Q000295:instrumentation* / Q000379:methods