title: Ultrasound emitter localization in heterogeneous media.
abstract: A novel algorithm to accurately determine the location of an ultrasound source within heterogeneous media is presented. The method obtains a small spacial error of 748 microm+/-310 microm for 100 different measurements inside a circular area with 140 mm diameter. The new algorithm can be used in targeted drug delivery for cancer therapies as well as to accurately locate any kind of ultrasound sources in heterogeneous media, such as ultrasonically marked medical devices or tumors.
authors.affiliation: Institute of Robotics and Intelligent Systems, ETH Zurich, 8092 Zurich, Switzerland. mflueckiger@ethz.ch
authors.forename: Michael
authors.initials: M
authors.lastname: Flückiger
authors.forename: Bradley J
authors.initials: BJ
authors.lastname: Nelson
mesh_terms: D000465:Algorithms; D000970:Antineoplastic Agents / Q000008:administration & dosage; D016503:Drug Delivery Systems; D020342:Finite Element Analysis; D006801:Humans; D009369:Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000188:drug therapy; D014465:Ultrasonics; D014463:Ultrasonography
chemical_list: D000970:Antineoplastic Agents