Synthesis and allylation at the all O-6 positions of cyclomaltohexaose.
A method for preparation of per-6-O-substituted cyclodextrin derivatives was developed. The thermostable cyclomaltodextrin glucanotransferase (CGTase) formed mainly cyclomaltohexaose 2 from amylose 1. The compound 2 was selectively converted to 3 without protection of the other hydroxyl groups by allylation at the all O-6 positions in excess base.
Huang
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G
College of Chemistry, Chongqing Normal University, Chongqing, China. huangdoctor226@163.com
Wong
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D002236:Carbohydrate Conformation; D009682:Magnetic Resonance Spectroscopy; D021241:Spectrometry, Mass, Electrospray Ionization; D047391:alpha-Cyclodextrins / Q000138:chemical synthesis* / Q000737:chemistry
D047391:alpha-Cyclodextrins; C032613:alpha-cyclodextrin