Differential functional coupling between human saphenous cryoallografts and arteries: importance of the arterial type and the biomechanical parameter evaluated.
The aim of this study was to characterize and compare human great saphenous veins (HGSVs), HGSV cryoallografts, expanded polytetrafluoroethylene (ePTFE) segments, and elastic and muscular arteries' biomechanics, so as to identify if the biomechanical coupling and the HGSV advantages with respect to ePTFE depend on the arterial type and/or on the biomechanical property considered. Pressure and diameter were measured in vitro, under arterial hemodynamic conditions, in elastic and muscular arteries, and in vascular substitutes: fresh and cryopreserved HGSV and ePTFE segments. The wall's dynamics (compliance, viscosity, and inertia), energy dissipation, and buffering were calculated. The coupling was quantified for each biomechanical parameter. Cryopreservation preserved HGSV biomechanics. The HGSV cryoallografts' dynamics, energetics, and buffering were lesser with respect to both arteries, but were higher than the ePTFE. The coupling differed, depending on the arterial type and property considered. The biomechanical coupling depended on the artery and property considered. HGSV cryoallograft advantages over ePTFE were arterial type and property independent.
Bia
Daniel
D
Departamento de Fisiología, Facultad de Medicina, Universidad de la República, Monteviedo, Uruguay.
Zócalo
Yanina
Y
Pessana
Franco
F
Armentano
Ricardo
R
Pérez
Héctor
H
Saldías
María
M
Alvarez
Inés
I
D000328:Adult; D000704:Analysis of Variance; D000714:Anastomosis, Surgical; D001696:Biomechanical Phenomena; D001783:Blood Flow Velocity; D001807:Blood Vessel Prosthesis; D001808:Blood Vessels / Q000637:transplantation*; D002339:Carotid Arteries / Q000502:physiology / Q000637:transplantation; D015925:Cryopreservation / Q000379:methods*; D005260:Female; D005263:Femoral Artery / Q000502:physiology / Q000637:transplantation; D006801:Humans; D008297:Male; D008962:Models, Theoretical; D011138:Polytetrafluoroethylene; D011336:Probability; D012501:Saphenous Vein / Q000637:transplantation*; D012680:Sensitivity and Specificity; D013718:Tensile Strength; D014019:Tissue Donors; D020858:Tissue and Organ Harvesting / Q000379:methods
D011138:Polytetrafluoroethylene