[Establishment of bitterness appraisal method of Chinese drugs and preparation].
OBJECTIVE
Bitterness appraisal method of Chinese drugs and preparation is established.


METHODS
The investigation table was designed by analogical epidemiology investigation. Then the statistical analysis was made for the data, and berberine bitter taste threshold was calculated. Verification experiment was made by two kinds of complex prescription.


RESULTS
Berberine is determined as the standard bitter material. Statistics results about verification experiment are significant.


CONCLUSIONS
The system could be bitterness appraisal method of Chinese drugs and preparation.
Wang
You-jie
YJ
Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Xu
De-sheng
DS
Feng
Yi
Y
D000328:Adult; D000367:Age Factors; D001599:Berberine / Q000737:chemistry*; D004311:Double-Blind Method; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal / Q000737:chemistry* / Q000302:isolation & purification; D006801:Humans; D010946:Plants, Medicinal / Q000737:chemistry; D013649:Taste / Q000502:physiology*; D013652:Taste Threshold
D004338:Drug Combinations; D004365:Drugs, Chinese Herbal; D001599:Berberine