New formation of imines of C19-diterpenoid alkaloids by heating with DMSO.
Treatment of some C(19)-diterpenoid alkaloids (3, 6, 10 and 12) with anhydrous DMSO at 100-170 degrees C for 3-7 h led to the formation of the corresponding imines (4, 7/8, 11, 13/14) in 65-83% yield, respectively. This is a new simpler formation of the imines of the C(19)-diterpenoid alkaloids.
He
Ya-Mei
YM
Department of Chemistry of Medicinal Natural Products, West China College of Pharmacy, Sichuan University, Chengdu, China.
Zou
Chun-Lan
CL
Chen
Qiao-Hong
QH
Wang
Feng-Peng
FP
D000470:Alkaloids / Q000737:chemistry*; D004121:Dimethyl Sulfoxide / Q000737:chemistry*; D004224:Diterpenes / Q000737:chemistry*; D007097:Imines / Q000138:chemical synthesis*; D021241:Spectrometry, Mass, Electrospray Ionization
D000470:Alkaloids; D004224:Diterpenes; D007097:Imines; D004121:Dimethyl Sulfoxide