title: Torasemide transport by organic anion transporters contributes to hyperuricemia.
authors.affiliation: Abteilung Vegetative Physiologie und Pathophysiologie, Georg August Universität, Göttingen, Germany. hagos@physiol.med.uni-goettingen.de
authors.forename: Yohannes
authors.initials: Y
authors.lastname: Hagos
authors.forename: Andrew
authors.initials: A
authors.lastname: Bahn
authors.forename: Stefan V
authors.initials: SV
authors.lastname: Vormfelde
authors.forename: Jürgen
authors.initials: J
authors.lastname: Brockmöller
authors.forename: Gerhard
authors.initials: G
authors.lastname: Burckhardt
mesh_terms: D000818:Animals; D000959:Antihypertensive Agents / Q000493:pharmacokinetics*; D001189:Aryl Hydrocarbon Hydroxylases / Q000378:metabolism; D001692:Biological Transport; D065729:Cytochrome P-450 CYP2C9; D006801:Humans; D033461:Hyperuricemia / Q000378:metabolism*; D007700:Kinetics; D008956:Models, Chemical; D009865:Oocytes / Q000378:metabolism; D027361:Organic Anion Transporters / Q000378:metabolism*; D010100:Oxygen / Q000378:metabolism; D021381:Protein Transport; D013449:Sulfonamides / Q000493:pharmacokinetics*; D000077786:Torsemide; D014162:Transfection; D014982:Xenopus laevis
chemical_list: D000959:Antihypertensive Agents; D027361:Organic Anion Transporters; D013449:Sulfonamides; C450260:CYP2C9 protein, human; D065729:Cytochrome P-450 CYP2C9; D001189:Aryl Hydrocarbon Hydroxylases; D010100:Oxygen; D000077786:Torsemide