title: Application of matrix solid-phase dispersion in the determination of acrylamide in potato chips.
abstract: A sample preparation technique based on matrix solid-phase dispersion (MSPD) was applied to the determination of acrylamide in potato chips. Samples (0.5 g) were ground and dispersed in C18 (2g), transferred to an empty column, and after a previous clean-up with n-hexane to eliminate fat, acrylamide was eluted with water (4 ml+4 ml). After bromination of the extract the samples were analysed by GC-MS in selected ion monitoring mode. The method presents good recoveries and the limits of detection and of quantification were 12.8 and 38.8 microg kg(-1), respectively. In order to evaluate the performance of the MSPD-GC/MS developed method, 17 potato chips samples were simultaneously analysed by an alternative method based on the extraction of acrylamide with hot water. The results obtained by using both methods were very similar, with a correlation factor (r) of 0.9985. The reported MSPD extraction method revealed to be simpler and faster then previous GC-MS methods used to quantify acrylamide in potato chips.
authors.affiliation: REQUIMTE, Serviço de Bromatologia, Faculdade de Farmácia, Universidade do Porto, Rua Aníbal Cunha, 164, 4099-030 Porto, Portugal. josefer@ff.up.pt
authors.forename: José O
authors.initials: JO
authors.lastname: Fernandes
authors.forename: Cristina
authors.initials: C
authors.lastname: Soares
mesh_terms: D020106:Acrylamide / Q000032:analysis*; D005504:Food Analysis / Q000379:methods*; D008401:Gas Chromatography-Mass Spectrometry; D011198:Solanum tuberosum / Q000737:chemistry*; D052616:Solid Phase Extraction / Q000379:methods*
chemical_list: D020106:Acrylamide