Tofisopam inhibits the pharmacokinetics of CYP3A4 substrate midazolam.
Tóth
Mária
M
Drabant
Sándor
S
Varga
Bálint
B
Végso
Gyula
G
Cseh
Anna
A
Szentpéteri
Imre
I
Klebovich
Imre
I
D000759:Adjuvants, Anesthesia / Q000493:pharmacokinetics*; D000928:Antidepressive Agents / Q000494:pharmacology*; D019540:Area Under Curve; D001569:Benzodiazepines / Q000494:pharmacology*; D051544:Cytochrome P-450 CYP3A / Q000187:drug effects* / Q000378:metabolism; D004347:Drug Interactions; D006207:Half-Life; D006801:Humans; D007413:Intestinal Mucosa / Q000378:metabolism; D007422:Intestines / Q000187:drug effects; D008099:Liver / Q000187:drug effects / Q000378:metabolism; D008297:Male; D008874:Midazolam / Q000493:pharmacokinetics*
D000759:Adjuvants, Anesthesia; D000928:Antidepressive Agents; D001569:Benzodiazepines; D051544:Cytochrome P-450 CYP3A; C510163:CYP3A4 protein, human; D008874:Midazolam; C012582:tofisopam