title: Methicillin-resistant Staphylococcus aureus hepatic abscess in a patient with sickle-cell disease.
abstract: We report a case of a 16-year-old female patient with sickle-cell disease with a liver abscess secondary to methicillin-resistant Staphylococcus aureus (MRSA). She had initially presented with jaundice and abdominal pain and subsequently underwent endoscopic retrograde cholangio-pancreaticography followed by laparoscopic cholecystectomy for removal of gallstones. However, post-cholecystectomy she presented with generalized abdominal pain and computed tomography scan of the abdomen revealed a liver abscess. A pigtail catheter was inserted into the abscess and culture of the aspirate yielded MRSA (susceptibility pattern of the organism was compatible with community-acquired MRSA). She was treated with intravenous clindamycin for 6 weeks with complete resolution of the abscess.
authors.affiliation: Department of Pediatrics, University of South Alabama College of Medicine, Mobile, AL 36604, USA. mmancao@usouthal.edu
authors.forename: M
authors.initials: M
authors.lastname: Mancao
authors.forename: B
authors.initials: B
authors.lastname: Estrada
authors.forename: F
authors.initials: F
authors.lastname: Wilson
authors.forename: M
authors.initials: M
authors.lastname: Figarola
authors.forename: R
authors.initials: R
authors.lastname: Wesenberg
mesh_terms: D000293:Adolescent; D000755:Anemia, Sickle Cell / Q000150:complications* / Q000000981:diagnostic imaging / Q000382:microbiology; D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D017081:Cholecystectomy, Laparoscopic; D002981:Clindamycin / Q000008:administration & dosage; D024881:Drug Resistance, Bacterial; D005260:Female; D006801:Humans; D007262:Infusions, Intravenous; D008100:Liver Abscess / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000209:etiology* / Q000382:microbiology; D008712:Methicillin; D011859:Radiography; D013203:Staphylococcal Infections / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000209:etiology* / Q000382:microbiology; D013211:Staphylococcus aureus / Q000254:growth & development* / Q000302:isolation & purification
chemical_list: D000900:Anti-Bacterial Agents; D002981:Clindamycin; D008712:Methicillin