Comparison of the human immunodeficiency virus (HIV) type 1-specific immunoglobulin G capture enzyme-linked immunosorbent assay and the avidity index method for identification of recent HIV infections.
The sensitivity and specificity of the human immunodeficiency virus (HIV) type 1-specific immunoglobulin G capture enzyme-linked immunosorbent assay (BED-CEIA) were compared with those of the avidity index method to identify recent HIV infection using a panel of 148 samples (81 patients) representing durations of infection ranging from 0 to 222 weeks. The results from the two tests were similar (sensitivity of 80% versus 74% [P = 0.53]; specificity of 86% versus 82% [P = 0.67]).
Loschen
Stephan
S
Project HIV Variability and Molecular Epidemiology, Robert Koch Institute, Nordufer 20, 13353 Berlin, Germany.
Bätzing-Feigenbaum
Jörg
J
Poggensee
Gabriele
G
Cordes
Christiane
C
Hintsche
Bettina
B
Rausch
Michael
M
Dupke
Stephan
S
Gohlke-Micknis
Silvia
S
Rödig
Jana
J
Hamouda
Osamah
O
Kücherer
Claudia
C
D000328:Adult; D000915:Antibody Affinity; D004797:Enzyme-Linked Immunosorbent Assay / Q000379:methods*; D015483:HIV Antibodies / Q000097:blood*; D015658:HIV Infections / Q000175:diagnosis* / Q000821:virology; D015497:HIV-1 / Q000276:immunology*; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood*; D012680:Sensitivity and Specificity
D015483:HIV Antibodies; D007074:Immunoglobulin G