title: Comparison of optimized and standard diffusion-weighted imaging at 1.5T for the detection of acute lesions in patients with transient ischemic attack.
abstract: The high rate of normal diffusion-weighted imaging (DWI) in patients with transient ischemic attack (TIA) raises the question as to its sensitivity for detecting small ischemic lesions. We compared standard and optimized DWI in 36 consecutive patients with TIA. Optimized DWI was positive in more patients than standard DWI (19 versus 16; P < .001) and showed more lesions (56 versus 42; P = .002). At 1.5T, optimizing DWI decreases the rate of false-negative DWI in patients with TIA.
authors.affiliation: Department of Neuroradiology, Université Paris Descartes, Centre Hospitalier Sainte-Anne, Paris, France.
authors.forename: A
authors.initials: A
authors.lastname: Bertrand
authors.forename: C
authors.initials: C
authors.lastname: Oppenheim
authors.forename: C
authors.initials: C
authors.lastname: Lamy
authors.forename: S
authors.initials: S
authors.lastname: Rodrigo
authors.forename: O
authors.initials: O
authors.lastname: Naggara
authors.forename: J L
authors.initials: JL
authors.lastname: Mas
authors.forename: J F
authors.initials: JF
authors.lastname: Meder
mesh_terms: D000368:Aged; D001921:Brain / Q000473:pathology*; D038524:Diffusion Magnetic Resonance Imaging / Q000379:methods*; D017352:Echo-Planar Imaging / Q000379:methods*; D005188:False Negative Reactions; D005260:Female; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D002546:Ischemic Attack, Transient / Q000175:diagnosis*; D008297:Male; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity