title: Studies on the oxygenation of human blood by photocatalytic action.
abstract: The present article gave the proof of concept for oxygenating human blood using the established principles of photocatalytic action of anatase TiO2 thin films in generating oxygen from water. The photocatalytic action involves the absorption of the UV optical energy (365 nm) to split water available in the blood into oxygen and hydrogen, and the generated oxygen is attached to the hemoglobin. In the present study, an enhanced catalytic action was achieved by preparing the nanosized anatase TiO2 thin films on tin-doped indium oxide (ITO) thin films, forming TiO2/ITO semiconducting junction. These TiO2 and ITO thin films and the semiconducting junctions were grown by the reactive DC Magnetron sputtering technique (using pure metallic targets) at room temperature (300 K) and subsequently annealed at 870 K for 60 min. The annealing process (i) influenced the formation of the anatase phase of TiO2; and (ii) diffused indium from ITO into TiO2, forming InTi(2)O(5). The work functions of ITO and InTi(2)O(5) were measured to be 4.72 and 4.76 eV, respectively. The higher efficacy of the photocatalytic action was attributed to the lower work function of ITO. The results clearly show that the photocatalytic action increases the oxygen content in the blood significantly.
authors.affiliation: Department of Physics, Indian Institute of Technology Madras, Chennai, India. manu@iitm.ac.in
authors.forename: Aryasomayajula
authors.initials: A
authors.lastname: Subrahmanyam
authors.forename: Thevasahayam
authors.initials: T
authors.lastname: Arokiadoss
authors.forename: T Paul
authors.initials: TP
authors.lastname: Ramesh
mesh_terms: D004912:Erythrocytes / Q000378:metabolism; D006454:Hemoglobins / Q000378:metabolism; D006801:Humans; D010100:Oxygen / Q000097:blood*; D010777:Photochemistry / Q000379:methods*; D017319:Photosensitizing Agents / Q000494:pharmacology*; D012680:Sensitivity and Specificity; D014025:Titanium / Q000494:pharmacology*; D014466:Ultraviolet Rays
chemical_list: D006454:Hemoglobins; D017319:Photosensitizing Agents; C009495:titanium dioxide; D014025:Titanium; D010100:Oxygen