title: [NK cells in malignant diseases].
abstract: Data dealing with the role of NK cells in the defense of malignancy, are given. The results of human studies of impaired NK cell activity in various malignancies which show further decrease with the advance of the disease, are described in detail. Causes of diminished NK cell activity are discussed, and the important effects of sera on this activity are pointed out. Characteristics of NK cell subpopulations are given, as well as the possibility of their activation in vivo and in vitro in terms of adoptive immunotherapy.
authors.forename: G
authors.initials: G
authors.lastname: Konjević
authors.forename: I
authors.initials: I
authors.lastname: Spuzić
mesh_terms: D006801:Humans; D007694:Killer Cells, Natural / Q000276:immunology*; D009369:Neoplasms / Q000276:immunology*