title: Simultaneous measurement of eye stiffness and contact area for living human eyes.
abstract: Goldmann applanation tonometry is commonly used for measuring IOP (IntraOcular Pressure) to diagnose glaucoma. However, the measured IOP by the applanation tonometry is valid only under the assumption that all the subjects have the same structural eye stiffness. Abnormal eye stiffness makes abnormal corneal deformation and thus the current applanation tonometer misestimates the IOP. This study challenges to measure the eye stiffness in vivo with a non-invasive approach for detecting the abnormal deformation. The deformation of the cornea and the contact area between the probe and the cornea are simultaneously captured by cameras during the experiment. Experimental results show that some subjects have different relationship among the force, the displacement and the contact area even with same IOP. The proposed eye stiffness measurement can help detecting the abnormal deformation and the eyes with misestimated IOP.
authors.affiliation: Graduate School of Information Science, Nara Institute of Science and Technology (NAIST), Takayama-Chou 8916-5, Ikoma, Nara 630-0192, Japan. kurita@is.naist.jp
authors.forename: Yuichi
authors.initials: Y
authors.lastname: Kurita
authors.forename: Yoshichika
authors.initials: Y
authors.lastname: Iida
authors.forename: Makoto
authors.initials: M
authors.lastname: Kaneko
authors.forename: Hiromu K
authors.initials: HK
authors.lastname: Mishima
authors.forename: Seiki
authors.initials: S
authors.lastname: Katakura
authors.forename: Yoshiaki
authors.initials: Y
authors.lastname: Kiuchi
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003315:Cornea / Q000503:physiopathology; D005123:Eye / Q000503:physiopathology*; D005901:Glaucoma / Q000503:physiopathology; D006801:Humans; D007429:Intraocular Pressure; D008875:Middle Aged; D014065:Tonometry, Ocular / Q000295:instrumentation / Q000379:methods*