title: [Establishment of bitterness appraisal method of Chinese drugs and preparation].
abstract: OBJECTIVE
  Bitterness appraisal method of Chinese drugs and preparation is established.
  
  
  METHODS
  The investigation table was designed by analogical epidemiology investigation. Then the statistical analysis was made for the data, and berberine bitter taste threshold was calculated. Verification experiment was made by two kinds of complex prescription.
  
  
  RESULTS
  Berberine is determined as the standard bitter material. Statistics results about verification experiment are significant.
  
  
  CONCLUSIONS
  The system could be bitterness appraisal method of Chinese drugs and preparation.
authors.affiliation: Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
authors.forename: You-jie
authors.initials: YJ
authors.lastname: Wang
authors.forename: De-sheng
authors.initials: DS
authors.lastname: Xu
authors.forename: Yi
authors.initials: Y
authors.lastname: Feng
mesh_terms: D000328:Adult; D000367:Age Factors; D001599:Berberine / Q000737:chemistry*; D004311:Double-Blind Method; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal / Q000737:chemistry* / Q000302:isolation & purification; D006801:Humans; D010946:Plants, Medicinal / Q000737:chemistry; D013649:Taste / Q000502:physiology*; D013652:Taste Threshold
chemical_list: D004338:Drug Combinations; D004365:Drugs, Chinese Herbal; D001599:Berberine