title: T-wave alternans analysis improvement by means of curve alignment prior to distance calculation.
abstract: Tracking of repolarization instabilities in the ECG, such as T-wave alternans (TWA), has become a popular non-invasive method to assess the vulnerability to malignant arrhythmic events. These instabilities are usually characterized by small amplitude changes and their measurement is difficult due to the presence of noise and artifacts. Several methods have been recently proposed to address this problem. Most of them are based on amplitude analysis of beat-to-beat alternation of the T wave. This paper describes a preprocessing stage intended to be used prior to amplitude analysis and aimed at improving the alignment between consecutive T waves. This increases the accuracy of the difference calculation.
authors.affiliation: Department of Computer Science, Polytechnic University of Valencia, Alcoi Campus, Alcoi, Spain. dcuesta@disca.upv.es
authors.forename: David
authors.initials: D
authors.lastname: Cuesta-Frau
authors.forename: Marcelo
authors.initials: M
authors.lastname: Biagetti
authors.forename: Pau
authors.initials: P
authors.lastname: Micó-Tormos
authors.forename: Mateo
authors.initials: M
authors.lastname: Aboy
authors.forename: Ricardo
authors.initials: R
authors.lastname: Quinteiro
mesh_terms: D001145:Arrhythmias, Cardiac / Q000503:physiopathology*; D004562:Electrocardiography / Q000379:methods; D001330:Electronic Data Processing / Q000379:methods*; D006801:Humans; D008955:Models, Cardiovascular