title: [Simultaneous occurrence of localized plasmacytoma in hands and feet bones].
abstract: Localized plasmacytomas in the bones account for less than 10% of all myelomas. Axial skeletal bones are most commonly affected, while isolated lesions in the hands and feet are very rare. Simultaneous occurrence of localized lesions on both hands and feet has not been reported so far. We repor on a female patient, 40 years old, whose symptoms developed simultaneosly: pain and deformity of the hands and feet were radiologically confirmed as numerous cystic transilluminations and destruction of the bones. Specific diagnostic procedures in the affected bones showed moderately differentiated plasmacytoma with lamda light-chains. Serum and urine analysis revealed a monoclonal component (lambda light-chains). The patient received local radiotherapy and combined chemotherapy. Subsequently, bone changes regressed, and monoclonal protein disappeared from both serum and urine. Four years after the onset of the disease the phalanx of the left hand was punctured confirming the absence of plasmacytoma.
authors.forename: N
authors.initials: N
authors.lastname: Antonijević
authors.forename: N
authors.initials: N
authors.lastname: Radosević-Radojković
authors.forename: M
authors.initials: M
authors.lastname: Colović
authors.forename: M
authors.initials: M
authors.lastname: Atanacković
authors.forename: Z
authors.initials: Z
authors.lastname: Rolović
mesh_terms: D000328:Adult; D001859:Bone Neoplasms / Q000175:diagnosis* / Q000473:pathology; D005260:Female; D005529:Foot Bones; D050276:Hand Bones; D006801:Humans; D009101:Multiple Myeloma / Q000175:diagnosis* / Q000473:pathology