title: Mesenteric fibromatosis. Case report.
abstract: Deep fibromatosis is a rare locally aggressive but not metastasizing proliferation. Intra-abdominal fibromatosis (IAF) occurs either in association with Gardner's syndrome or as a sporadic event and presents in most cases differential diagnostic problems with myofibroblastic or fibroblastic tumors, characterized by a more aggressive biological behaviour such as gastrointestinal stromal tumors (GISTs). In absence of loco-regional and/or distant metastasis differential diagnosis may be difficult and represents a topical issue, since it influences treatment choice. We describe the case of a patient with sporadic IAF in which the tumor locally involved the mesentery and presented no loco-regional and distant spread. On histology, some morphological features of the neoplasm were in common with a GIST. Definitive diagnosis was made, postoperatively, on the basis of immunohistochemical findings.
authors.affiliation: Department of Surgery P. Valdoni, University of Rome La Sapienza, Rome, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Giuliani
authors.forename: M
authors.initials: M
authors.lastname: Demoro
authors.forename: A
authors.initials: A
authors.lastname: Ciardi
authors.forename: M
authors.initials: M
authors.lastname: Scimó
authors.forename: F
authors.initials: F
authors.lastname: Galati
authors.forename: M T
authors.initials: MT
authors.lastname: Lonardo
authors.forename: G
authors.initials: G
authors.lastname: Galati
mesh_terms: D000008:Abdominal Neoplasms / Q000175:diagnosis* / Q000473:pathology; D003937:Diagnosis, Differential; D005350:Fibroma / Q000175:diagnosis* / Q000473:pathology; D005736:Gardner Syndrome / Q000473:pathology; D006801:Humans; D008297:Male; D008643:Mesentery / Q000473:pathology; D008875:Middle Aged