Enteropathogen Resource Integration Center (ERIC): bioinformatics support for research on biodefense-relevant enterobacteria.
ERIC, the Enteropathogen Resource Integration Center (www.ericbrc.org), is a new web portal serving as a rich source of information about enterobacteria on the NIAID established list of Select Agents related to biodefense-diarrheagenic Escherichia coli, Shigella spp., Salmonella spp., Yersinia enterocolitica and Yersinia pestis. More than 30 genomes have been completely sequenced, many more exist in draft form and additional projects are underway. These organisms are increasingly the focus of studies using high-throughput experimental technologies and computational approaches. This wealth of data provides unprecedented opportunities for understanding the workings of basic biological systems and discovery of novel targets for development of vaccines, diagnostics and therapeutics. ERIC brings information together from disparate sources and supports data comparison across different organisms, analysis of varying data types and visualization of analyses in human and computer-readable formats.
Glasner
Jeremy D
JD
Genome Center, University of Wisconsin, 425G Henry Mall, Madison, Madison, WI 53703, USA. jglasner@wisc.edu
Plunkett
Guy
G
Anderson
Bradley D
BD
Baumler
David J
DJ
Biehl
Bryan S
BS
Burland
Valerie
V
Cabot
Eric L
EL
Darling
Aaron E
AE
Mau
Bob
B
Neeno-Eckwall
Eric C
EC
Pot
David
D
Qiu
Yu
Y
Rissman
Anna I
AI
Worzella
Sara
S
Zaremba
Sam
S
Fedorko
Joel
J
Hampton
Tom
T
Liss
Paul
P
Rusch
Michael
M
Shaker
Matthew
M
Shaull
Lorie
L
Shetty
Panna
P
Thotakura
Silpa
S
Whitmore
Jon
J
Blattner
Frederick R
FR
Greene
John M
JM
Perna
Nicole T
NT
D001426:Bacterial Proteins / Q000737:chemistry / Q000145:classification / Q000235:genetics; D035843:Biomedical Research; D023482:Bioterrorism; D019295:Computational Biology; D004251:DNA Transposable Elements; D030541:Databases, Genetic; D004755:Enterobacteriaceae / Q000235:genetics*; D004756:Enterobacteriaceae Infections / Q000175:diagnosis / Q000517:prevention & control / Q000628:therapy; D016680:Genome, Bacterial; D023281:Genomics; D020407:Internet; D020411:Oligonucleotide Array Sequence Analysis; D040901:Proteomics; D016415:Sequence Alignment; D012984:Software; D018511:Systems Integration
D001426:Bacterial Proteins; D004251:DNA Transposable Elements