title: Copper/silver-cocatalyzed Conia-ene reaction of linear beta-alkynic beta-ketoesters.
abstract: A novel and general copper/silver catalytic system has been developed for the Conia-ene intramolecular reaction of linear beta-alkynic beta-ketoesters. In the presence of (CuOTf)2.C6H6 and AgSbF6 (or AgOAc), a variety of the linear beta-alkynic beta-ketoesters selectively underwent the Conia-ene intramolecular reaction in moderate to good yields.
authors.affiliation: Key Laboratory of Chemical Biology & Traditional Chinese Medicine Research (Ministry of Education), Hunan Normal University, Changsha 410081, China.
authors.forename: Chen-Liang
authors.initials: CL
authors.lastname: Deng
authors.forename: Ren-Jie
authors.initials: RJ
authors.lastname: Song
authors.forename: Sheng-Mei
authors.initials: SM
authors.lastname: Guo
authors.forename: Zhi-Qiang
authors.initials: ZQ
authors.lastname: Wang
authors.forename: Jin-Heng
authors.initials: JH
authors.lastname: Li
mesh_terms: D000480:Alkynes / Q000737:chemistry*; D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D004952:Esters / Q000138:chemical synthesis* / Q000737:chemistry*; D007659:Ketones / Q000737:chemistry*; D015394:Molecular Structure; D012834:Silver / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D000480:Alkynes; D004952:Esters; D007659:Ketones; D012834:Silver; D003300:Copper