title: Functionalized chiral ionic liquid catalyzed enantioselective desymmetrizations of prochiral ketones via asymmetric Michael addition reaction.
abstract: Functionalized chiral ionic liquids were found to be highly effective and reusable organocatalysts for asymmetric Michael additions of 4-substituted cyclohexanones. The desymmetrization reaction afforded the desired Michael adducts bearing three carbon stereocenters with up to 99% ee.
authors.affiliation: Beijing National Laboratory for Molecular Sciences (BNLMS), Center for Chemical Biology, Institute of Chemistry, Chinese Academy of Sciences, Beijing, China. luosz@iccas.ac.cn
authors.forename: Sanzhong
authors.initials: S
authors.lastname: Luo
authors.forename: Long
authors.initials: L
authors.lastname: Zhang
authors.forename: Xueling
authors.initials: X
authors.lastname: Mi
authors.forename: Yupu
authors.initials: Y
authors.lastname: Qiao
authors.forename: Jin-Pei
authors.initials: JP
authors.lastname: Cheng
mesh_terms: D002244:Carbon / Q000737:chemistry; D002384:Catalysis; D003512:Cyclohexanones / Q000737:chemistry; D052578:Ionic Liquids / Q000737:chemistry*; D007659:Ketones / Q000737:chemistry*; D008956:Models, Chemical; D008958:Models, Molecular; D013237:Stereoisomerism
chemical_list: D003512:Cyclohexanones; D052578:Ionic Liquids; D007659:Ketones; D002244:Carbon