title: [pH value and potassium level of diagnostic peritoneal lavage fluid in the early diagnosis of acute mesenteric ischemia secondary to arterial occlusion in rats].
abstract: BACKGROUND
  In this experimental study we evaluated the pH and potassium changes of the peritoneal irrigation fluid in the early phase of mesenteric ischemia.
  
  
  METHODS
  The Wistar albino rats were assigned randomly to 5 equal groups of 10 rats: sham operation, 30, 60, 120 and 180 minutes ischemia by arterial occlusion. We enregistred the ranges of pH and potassium in peritoneal irrigation fluid and serum pH.
  
  
  RESULTS
  Lower pH and increased potassium levels in peritoneal irrigation fluid were observed in 30 and 60 min ischemia groups. In 120 and 180 ischemia groups the level of pH continued to be lower and potassium level increased gradually, the serum pH were markedly lower in these groups. Histological analysis showed a positive correlation between the intestinal injury and ischemia time.
  
  
  CONCLUSIONS
  In contrast to sham group, increase in potassium and decrease in in pH levels in peritoneal irrigation fluid were seen in 30 and 60 min ischemia groups. The decrease of serum pH was enregistred after 120 min of ischemia. In early phase the measurement of potassium and pH in peritoneal irrigation fluid may be an early diagnostic tool for mesenteric ischemia.
authors.affiliation: Department of General Surgery, Taksim Training and Research Hospital, Istanbul, Turkey. dogangonullu@yahoo.com
authors.forename: Doğan
authors.initials: D
authors.lastname: Gönüllü
authors.forename: Yücel
authors.initials: Y
authors.lastname: Yankol
authors.forename: Ferruh
authors.initials: F
authors.lastname: Işiman
authors.forename: Ayşenur
authors.initials: A
authors.lastname: Akyildiz Iğdem
authors.forename: Osman
authors.initials: O
authors.lastname: Yücel
authors.forename: Ferda Nihat
authors.initials: FN
authors.lastname: Köksoy
mesh_terms: D000818:Animals; D001202:Ascitic Fluid / Q000737:chemistry*; D006863:Hydrogen-Ion Concentration; D007511:Ischemia / Q000097:blood / Q000175:diagnosis* / Q000503:physiopathology; D008641:Mesenteric Vascular Occlusion / Q000097:blood / Q000175:diagnosis* / Q000503:physiopathology; D008643:Mesentery / Q000098:blood supply*; D010533:Peritoneal Lavage; D011188:Potassium / Q000032:analysis; D011237:Predictive Value of Tests; D051381:Rats; D017208:Rats, Wistar
chemical_list: D011188:Potassium