title: Sophistication of foldamer form and function in vitro and in vivo.
abstract: Advances in the foldamer field in recent years are as diverse as the backbones of which they are composed. Applications have ranged from cellular penetration and membrane disruption to discrete molecular recognition, while efforts to control the complex geometric shape of foldamers has entered the realm of tertiary and quaternary structure. This review will provide recent examples of progress in the foldamer field, highlighting the significance of this class of compounds and the advances that have been made towards exploiting their full potential.
authors.affiliation: Department of Chemistry, Yale University, New Haven, CT 06520, USA.
authors.forename: Arjel D
authors.initials: AD
authors.lastname: Bautista
authors.forename: Cody J
authors.initials: CJ
authors.lastname: Craig
authors.forename: Elizabeth A
authors.initials: EA
authors.lastname: Harker
authors.forename: Alanna
authors.initials: A
authors.lastname: Schepartz
mesh_terms: D000818:Animals; D002460:Cell Line; D006801:Humans; D008958:Models, Molecular; D008968:Molecular Conformation; D010455:Peptides / Q000737:chemistry*; D011108:Polymers / Q000737:chemistry* / Q000378:metabolism
chemical_list: D010455:Peptides; D011108:Polymers