Covariant stringlike dynamics of scroll wave filaments in anisotropic cardiac tissue.
It has been hypothesized that stationary scroll wave filaments in cardiac tissue describe a geodesic in a curved space whose metric is the inverse diffusion tensor. Several numerical studies support this hypothesis, but no analytical proof has been provided yet for general anisotropy. In this Letter, we derive dynamic equations for the filament in the case of general anisotropy. These equations are covariant under general spatial coordinate transformations and describe the motion of a stringlike object in a curved space whose metric tensor is the inverse diffusion tensor. Therefore the behavior of scroll wave filaments in excitable media with anisotropy is similar to the one of cosmic strings in a curved universe. Our dynamic equations are valid for thin filaments and for general anisotropy. We show that stationary filaments obey the geodesic equation.
Verschelde
Henri
H
Department of Mathematical Physics and Astronomy, Ghent University, Krijgslaan 281, 9000 Ghent, Belgium.
Dierckx
Hans
H
Bernus
Olivier
O
D008841:Actin Cytoskeleton / Q000737:chemistry* / Q000502:physiology; D000465:Algorithms; D016880:Anisotropy; D002450:Cell Communication / Q000502:physiology; D004058:Diffusion; D006321:Heart / Q000502:physiology*