title: Perianeurysm edema with second-generation bioactive coils.
abstract: BACKGROUND
  Perianeurysm edema is an uncommon complication of intracranial aneurysms, occurring mostly in giant aneurysms that suddenly thrombose.
  
  
  METHODS
  We present the first report of an unruptured, nongiant, saccular aneurysm that developed marked perianeurysm edema after embolization with Matrix2 coils. In this case, follow-up catheter angiography showed a new coil tail protruding beyond the dome of the aneurysm in the region of the most intense edema.
  
  
  CONCLUSIONS
  We postulate that perianeurysm edema may occur after breakdown of the aneurysm wall accompanied by an inflammatory response to exposed bioactive coils. Clinicians should be aware of this potential complication and consider performing earlier surveillance angiography when this occurs to ensure that there has not been a shift in the coil mass and recurrence of the aneurysm.
authors.affiliation: Division of Interventional Neuroradiology, Department of Radiology, Inova Fairfax Hospital, Falls Church, VA 22042, USA. franklin.marden@inova.com
authors.forename: Franklin A
authors.initials: FA
authors.lastname: Marden
authors.forename: Christopher M
authors.initials: CM
authors.lastname: Putman
mesh_terms: D000328:Adult; D001672:Biocompatible Materials / Q000009:adverse effects*; D001929:Brain Edema / Q000000981:diagnostic imaging / Q000209:etiology* / Q000628:therapy; D004621:Embolization, Therapeutic / Q000009:adverse effects* / Q000295:instrumentation*; D005260:Female; D006801:Humans; D002532:Intracranial Aneurysm / Q000628:therapy*; D019344:Lactic Acid / Q000009:adverse effects*; D011100:Polyglycolic Acid / Q000009:adverse effects*; D000077182:Polylactic Acid-Polyglycolic Acid Copolymer; D011859:Radiography
chemical_list: D001672:Biocompatible Materials; D000077182:Polylactic Acid-Polyglycolic Acid Copolymer; D011100:Polyglycolic Acid; D019344:Lactic Acid