title: Severe varicella caused by varicella-vaccine strain in a child with significant T-cell dysfunction.
abstract: In March 1995, the US Food and Drug Administration approved a live attenuated varicella vaccine for use in healthy children 12 months to 12 years old. We report here an 18-month-old girl with cell-mediated immunodeficiency who developed a severe vaccine-associated rash and clinical evidence of vaccine-associated pneumonia 1 month after inadvertent receipt of varicella vaccine.
authors.affiliation: Department of Pediatrics, New York University School of Medicine, New York, New York, USA. jeanphilippep@niaid.nih.gov
authors.forename: Patrick
authors.initials: P
authors.lastname: Jean-Philippe
authors.forename: Abigail
authors.initials: A
authors.lastname: Freedman
authors.forename: Mary Wu
authors.initials: MW
authors.lastname: Chang
authors.forename: Sharon P
authors.initials: SP
authors.lastname: Steinberg
authors.forename: Anne A
authors.initials: AA
authors.lastname: Gershon
authors.forename: Philip S
authors.initials: PS
authors.lastname: LaRussa
authors.forename: William
authors.initials: W
authors.lastname: Borkowsky
mesh_terms: D002644:Chickenpox / Q000175:diagnosis / Q000209:etiology* / Q000276:immunology*; D019433:Chickenpox Vaccine / Q000009:adverse effects*; D005260:Female; D006801:Humans; D007153:Immunologic Deficiency Syndromes / Q000150:complications / Q000276:immunology; D007223:Infant; D013601:T-Lymphocytes / Q000276:immunology*
chemical_list: D019433:Chickenpox Vaccine