Minimal distensibility of pulmonary capillaries in avian lungs compared with mammalian lungs.
Previous physiological studies suggest that avian pulmonary capillaries behave like almost rigid tubes. We made morphometric measurements to determine the diameter of the capillaries in chicken lungs when the transmural pressure was altered over a wide range. The diameter of avian pulmonary capillaries increased by only 13% when the pressure inside them was raised from 0 to 25 cmH(2)O. In contrast, other studies have shown that the mean width of the pulmonary capillaries in dogs increased by about 125% and in cats by 128% for the same pressure change. Furthermore, raising the pressure 35 cmH(2)O outside the capillaries compared to the pressure inside the capillaries in chicken lungs caused little change in diameter whereas under the same conditions in mammal lungs the capillaries are completely collapsed. We conclude that the epithelial bridges between the blood capillaries in the bird lung provide strong support to the capillaries both in expansion and compression.
Watson
Rebecca R
RR
Department of Medicine, University of California San Diego, La Jolla, CA 92093-0623, United States.
Fu
Zhenxing
Z
West
John B
JB
D000222:Adaptation, Physiological; D000704:Analysis of Variance; D000818:Animals; D001794:Blood Pressure; D002196:Capillaries / Q000502:physiology / Q000648:ultrastructure*; D002200:Capillary Resistance / Q000502:physiology*; D002645:Chickens / Q000033:anatomy & histology* / Q000502:physiology; D004548:Elasticity; D005260:Female; D006439:Hemodynamics / Q000502:physiology; D008168:Lung / Q000098:blood supply / Q000648:ultrastructure*; D008322:Mammals; D008833:Microcirculation; D011652:Pulmonary Circulation / Q000502:physiology; D013045:Species Specificity