title: Neonates with left-sided obstructive heart disease: clinical manifestation and management at primary care hospitals.
abstract: BACKGROUND
  In neonates, left-sided obstructive heart defects are critical diseases requiring early recognition, initial stabilization, and transfer to Cardiac Center.
  
  
  OBJECTIVE
  To assess management of these neonates in primary care hospitals.
  
  
  METHODS
  Retrospective analysis of medical records of neonates admitted to Cardiac Intensive Care Unit in whom diagnosis of left-sided obstructive heart defect was established.
  
  
  RESULTS
  During 8-year period records of 117 patients were evaluated. Of those, 83 had hypoplastic left heart syndrome, 13 aortic stenosis, 12 coarctation of aorta, and 9 interruption of aortic arch. In 13 (11%) patients diagnosis of heart defect was established prenatally, other neonates presented postnatally with heart failure (28.2%), shock (65.4%) or severe cyanosis (4.8%). Continuous infusion of PGE1 and dopamine was administered in 84.6% and 30.8% patients, respectively. Thirty-two (30.8%) patients were mechanically ventilated and 36 (34.6%) received sodium bicarbonate. In referring hospitals the heart defect was most often diagnosed using echocardiography and diagnosis was established accurately in 55% patients.
  
  
  CONCLUSIONS
  The study showed that in primary care hospitals neonates with known or suspected left-sided obstructive heart disease need more aggressive resuscitative measures than those used in this patient series. Prenatal diagnosis rate of these heart defects is very low (Tab. 3, Fig. 1, Ref 8). Full Text (Free, PDF) www.bmj.sk.
authors.affiliation: Pediatric Cardiac Center, Bratislava, Slovakia. lkovacikova@yahoo.com
authors.forename: L
authors.initials: L
authors.lastname: Kovacikova
authors.forename: K
authors.initials: K
authors.lastname: Dakkak
authors.forename: P
authors.initials: P
authors.lastname: Skrak
authors.forename: M
authors.initials: M
authors.lastname: Zahorec
authors.forename: M
authors.initials: M
authors.lastname: Holan
mesh_terms: D001017:Aortic Coarctation / Q000175:diagnosis / Q000601:surgery; D001024:Aortic Valve Stenosis / Q000151:congenital / Q000175:diagnosis / Q000601:surgery; D005260:Female; D006801:Humans; D018636:Hypoplastic Left Heart Syndrome / Q000175:diagnosis / Q000601:surgery; D007231:Infant, Newborn; D008297:Male; D014694:Ventricular Outflow Obstruction / Q000151:congenital* / Q000175:diagnosis / Q000601:surgery