Case of recurrent paracoccidioidomycosis in female. 10 years after initial treatment.
This report describes a case of recurrence of chronic paracoccidioidomycosis 10 years following the initial diagnosis. A 56-year-old female was admitted to the Dental Clinic of the Pontifical Catholic University of Paraná complaining of oral soreness. Mulberry-like ulcerations were observed on the gingiva, right labial comissura, and vermillion of the lip. The patient reported persistent chronic cough, weight loss, appetite loss and fever. The anamnesis revealed that the patient had developed and been treated for paracoccidioidomycosis 10 years earlier. A biopsy was performed and microscopic examination revealed microabscesses, collections of macrophages organized into granulomas, multinucleated giant cells and Paracoccidioides brasiliensis. The patient was treated with Itraconazole and, the oral lesions disappeared within 3 months. Persistent follow-up examination in patients with a history of paracoccidioidomycosis is essential in the management of this disease.
De Azevedo Izidoro
Ana Claudia Santos
AC
Department of Stomatology, School of Dentistry, Pontifical Catholic University of Paraná, Curitiba, Paraná, Brazil.
Da Silva
Paulo Cesar
PC
De Oliveira Ribas
Marina
M
De Azevedo
Luciana Reis
LR
Machado
Maria Angela Naval
MA
De Lima
Antonio Adilson Soares
AA
D001706:Biopsy; D005260:Female; D005500:Follow-Up Studies; D015726:Giant Cells / Q000382:microbiology; D005882:Gingival Diseases / Q000382:microbiology*; D006801:Humans; D008047:Lip Diseases / Q000382:microbiology*; D008264:Macrophages / Q000382:microbiology; D008875:Middle Aged; D009059:Mouth Diseases / Q000382:microbiology*; D009061:Mouth Mucosa / Q000382:microbiology; D010228:Paracoccidioides / Q000302:isolation & purification; D010229:Paracoccidioidomycosis / Q000175:diagnosis*; D012008:Recurrence