True intranuclear inclusions in a melanocytic nevus: report of a case and review of the literature.
Melanocytic tumors commonly show intranuclear pseudo-inclusions or cytoplasmic invaginations within the nuclei of melanocytes. However, true intranuclear inclusions have rarely been described in melanocytic nevus cells. Herein, we describe the histologic, immunohistochemical and ultrastructural features of an additional case of an intradermal melanocytic nevus with true intranuclear inclusions.
Murphy
Michael J
MJ
Department of Dermatology, University of Connecticut Health Center, Farmington, CT 06030, USA. mimurphy@nso1.uchc.edu
Murphy
Lauren
L
Fang
Min
M
Cartun
Richard
R
Jurzyk
Ronald
R
Grant-Kels
Jane M
JM
D000328:Adult; D014408:Biomarkers, Tumor / Q000032:analysis; D002467:Cell Nucleus / Q000648:ultrastructure*; D005260:Female; D006801:Humans; D007124:Immunoenzyme Techniques; D045586:Intranuclear Inclusion Bodies / Q000648:ultrastructure*; D046529:Microscopy, Electron, Transmission; D009508:Nevus, Pigmented / Q000737:chemistry / Q000601:surgery / Q000648:ultrastructure*; D012878:Skin Neoplasms / Q000737:chemistry / Q000601:surgery / Q000648:ultrastructure*
D014408:Biomarkers, Tumor