Urinary tract infections in renal transplant recipients.
Urinary tract infection (UTI) is the most common infectious complication after renal transplantation. Although Escherichia coli remains the most common cause of UTI, Enterococcus spp and drug-resistant Enterobacteriaceae have emerged as important uropathogens in these patients. As a result, symptomatic UTIs warrant pathogen-specific antibiotic therapy guided by culture and susceptibility data. In the early transplant period, prophylaxis of UTI with trimethoprim-sulfamethoxazole is generally effective. Until the natural history and optimal management of asymptomatic bacteruria are better defined, therapy of asymptomatic bacteruria is generally unnecessary.
Alangaden
George
G
Division of Infectious Diseases, Wayne State University School of Medicine, 3900 John R, Suite 5930, Detroit, MI 48201, USA. galangaden@med.wayne.edu