[The change concentrations in the serum of immunoglobulins and alpha-1 atitrypsin in children with obstructive pulmonary diseases].
Total concentrations of IgA, IgM, IgG, IgE and alpha-antitypsin were determined in the sera of 50 children of different age with bronchial asthma and obstructive bronchitis and 20 healthy children as control group. By using radial immunodifusion method the total IgA, IgM, IgG and alpha-antitrypsin were determined. Significantly higher values of IgE (t=5.17; p<0.01) and alpha-1 antitrypsin (t=4.6; p<0.01) were found in group of seek children. No significant difference in concentrations of IgA, IgM and IgG. Higher values of IgE and alpha-antitrypsin suggesting their pathophysiologic significance in airway obstruction infection in children with chronic obstructive pulmonary diseases.
Miljković
D
D
Dzelebcjić
J
J
Kostić
N
N
D000293:Adolescent; D001991:Bronchitis / Q000097:blood*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007136:Immunoglobulins / Q000097:blood*; D008173:Lung Diseases, Obstructive / Q000097:blood*; D008297:Male; D000515:alpha 1-Antitrypsin / Q000097:blood*
D007136:Immunoglobulins; D000515:alpha 1-Antitrypsin