title: Objectively measured sedentary time, physical activity, and metabolic risk: the Australian Diabetes, Obesity and Lifestyle Study (AusDiab).
abstract: OBJECTIVE
  We examined the associations of objectively measured sedentary time and physical activity with continuous indexes of metabolic risk in Australian adults without known diabetes.
  
  
  METHODS
  An accelerometer was used to derive the percentage of monitoring time spent sedentary and in light-intensity and moderate-to-vigorous-intensity activity, as well as mean activity intensity, in 169 Australian Diabetes, Obesity and Lifestyle Study (AusDiab) participants (mean age 53.4 years). Associations with waist circumference, triglycerides, HDL cholesterol, resting blood pressure, fasting plasma glucose, and a clustered metabolic risk score were examined.
  
  
  RESULTS
  Independent of time spent in moderate-to-vigorous-intensity activity, there were significant associations of sedentary time, light-intensity time, and mean activity intensity with waist circumference and clustered metabolic risk. Independent of waist circumference, moderate-to-vigorous-intensity activity time was significantly beneficially associated with triglycerides.
  
  
  CONCLUSIONS
  These findings highlight the importance of decreasing sedentary time, as well as increasing time spent in physical activity, for metabolic health.
authors.affiliation: School of Population Health, University of Queensland, Brisbane, Australia. g.healy@uq.edu.au
authors.forename: Genevieve N
authors.initials: GN
authors.lastname: Healy
authors.forename: Katrien
authors.initials: K
authors.lastname: Wijndaele
authors.forename: David W
authors.initials: DW
authors.lastname: Dunstan
authors.forename: Jonathan E
authors.initials: JE
authors.lastname: Shaw
authors.forename: Jo
authors.initials: J
authors.lastname: Salmon
authors.forename: Paul Z
authors.initials: PZ
authors.lastname: Zimmet
authors.forename: Neville
authors.initials: N
authors.lastname: Owen
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001315:Australia / Q000453:epidemiology; D001794:Blood Pressure; D049628:Body Size; D003920:Diabetes Mellitus / Q000453:epidemiology / Q000517:prevention & control; D015444:Exercise; D006801:Humans; D007182:Income; D008019:Life Style; D008055:Lipids / Q000097:blood; D008875:Middle Aged; D009765:Obesity / Q000453:epidemiology* / Q000517:prevention & control; D018579:Patient Selection; D005082:Physical Exertion / Q000502:physiology; D012044:Regression Analysis; D012307:Risk Factors; D014280:Triglycerides / Q000097:blood*
chemical_list: D008055:Lipids; D014280:Triglycerides