title: Enhanced implant stability with a chemically modified SLA surface: a randomized pilot study.
abstract: OBJECTIVE
  Chemical modification to a sandblasted, large-grit, acid-etched (SLA) implant surface has been shown to enhance the rate of osseointegration. The goal of the present study was to examine changes in stability for implants with a chemically modified SLA surface and to compare their outcomes to those of control implants.
  
  
  METHODS
  A randomized controlled trial was conducted with 31 patients. Each patient received 2 implants with the same physical properties but with surfaces that were chemically different. The control implants had a standard SLA surface, while the test implants had a chemically modified surface. Resonance frequency analysis was assessed weekly over the first 6 weeks following implant placement.
  
  
  RESULTS
  All implants proved clinically successful, allowing for restoration. Most implants were placed in the mandible (50 of 62). A shift in implant stability from decreasing stability to increasing stability (P < .001), occurred after 2 weeks for the test implants and after 4 weeks for the control implants.
  
  
  CONCLUSIONS
  The findings from this pilot study provide clinical support for the potential for chemical modification of the SLA surface to alter biologic events during the osseointegration process and demonstrate levels of short-term clinical success similar to those observed for implants with an SLA surface.
authors.affiliation: Department of Periodontics, University of Texas Health Science Center at San Antonio, 78229-3900, USA. oates@uthscsa.edu
authors.forename: Thomas W
authors.initials: TW
authors.lastname: Oates
authors.forename: Pilar
authors.initials: P
authors.lastname: Valderrama
authors.forename: Mark
authors.initials: M
authors.lastname: Bischof
authors.forename: Rabah
authors.initials: R
authors.lastname: Nedir
authors.forename: Archie
authors.initials: A
authors.lastname: Jones
authors.forename: James
authors.initials: J
authors.lastname: Simpson
authors.forename: Helge
authors.initials: H
authors.lastname: Toutenburg
authors.forename: David L
authors.initials: DL
authors.lastname: Cochran
mesh_terms: D000134:Acid Etching, Dental; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D045662:Dental Etching; D015921:Dental Implants; D003764:Dental Materials / Q000737:chemistry*; D017267:Dental Prosthesis Design; D017268:Dental Prosthesis Retention; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008334:Mandible / Q000601:surgery; D008437:Maxilla / Q000601:surgery; D008875:Middle Aged; D016348:Osseointegration / Q000502:physiology*; D010865:Pilot Projects; D011446:Prospective Studies; D013499:Surface Properties; D016896:Treatment Outcome; D014732:Vibration; D014945:Wound Healing / Q000502:physiology
chemical_list: D015921:Dental Implants; D003764:Dental Materials