title: Catalytic enantioselective addition of arylboronic acids to N-boc imines generated in situ.
abstract: The rhodium-catalyzed addition of arylboronic acids to N-Boc imines generated in situ from stable and easily prepared alpha-carbamoyl sulfones has been developed. High enantioselectivities are observed for additions of arylboronic acids with a variety of steric and electronic properties.
authors.affiliation: Department of Chemistry, University of California, Berkeley, California 94720-1460, USA.
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Nakagawa
authors.forename: Jason C
authors.initials: JC
authors.lastname: Rech
authors.forename: Robert W
authors.initials: RW
authors.lastname: Sindelar
authors.forename: Jonathan A
authors.initials: JA
authors.lastname: Ellman
mesh_terms: D001897:Boronic Acids / Q000737:chemistry*; D002384:Catalysis; D007097:Imines / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D013237:Stereoisomerism
chemical_list: D001897:Boronic Acids; D007097:Imines