Copper-catalyzed enantioselective substitution of allylic carbonates with diboron: an efficient route to optically active alpha-chiral allylboronates.
A method for the synthesis of alpha-chiral allylboronates featuring the Cu(I)-catalyzed enantioselective substitution of readily available allylic carbonates with a diboron is described. Using this method, various alpha-chiral allylboronates, including functionalized allylboronates, were successfully synthesized, with high enantiomeric purity.
Ito
Hajime
H
Department of Chemistry, Faculty of Science, Hokkaido University, Sapporo 060-0810, Japan. hajito@sci.hokudai.ac.jp
Ito
Shinichiro
S
Sasaki
Yusuke
Y
Matsuura
Kou
K
Sawamura
Masaya
M