Bov-B-mobilized SINEs in vertebrate genomes.
Two new short retroposon families (SINEs) have been found in the genome of springhare Pedetes capensis (Rodentia). One of them, Ped-1, originated from 5S rRNA, while the other one, Ped-2, originated from tRNA-derived SINE ID. In contrast to most currently active mammalian SINEs mobilized by L1 long retrotransposon (LINE), Ped-1 and Ped-2 are mobilized by Bov-B, a LINE family of the widely distributed RTE clade. The 3' part of these SINEs originates from two sequences in the 5' and 3' regions of Bov-B. Such bipartite structure of the LINE-derived part has been revealed in all Bov-B-mobilized SINEs known to date (AfroSINE, Bov-tA, Mar-1, and Ped-1/2), which distinguishes them from other SINEs with only a 3' LINE-derived part. Structural analysis and the distribution of Bov-B LINEs and partner SINEs supports the horizontal transfer of Bov-B, while the SINEs emerged independently in lineages with this LINE.
Gogolevsky
Konstantin P
KP
Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 32 Vavilov Street, Moscow, Russia.
Vassetzky
Nikita S
NS
Kramerov
Dmitri A
DA
D000818:Animals; D001483:Base Sequence; D022761:Gene Transfer, Horizontal; D016678:Genome / Q000235:genetics*; D008969:Molecular Sequence Data; D012341:RNA, Ribosomal, 5S / Q000235:genetics; D012377:Rodentia / Q000235:genetics*; D020086:Short Interspersed Nucleotide Elements / Q000235:genetics*
D012341:RNA, Ribosomal, 5S