title: [Studies on chemical constituents of in herb Pyrola calliatha].
abstract: OBJECTIVE
  To investigate the chemical constituents of Pyrola calliatha.
  
  
  METHODS
  The chemical constituents were isolated by various column chromatographic methods. The structures were identified by spectral data.
  
  
  RESULTS
  Ten compounds were isolated and identified as chimaphilin (1), uvaol(2), ursolic acid (3), 2beta,3beta,23-trihydroxy-12-ene-28-ursolic acid (4), daucosterol (5), 2alpha,3beta,23,24-tetrahydroxy-12-ene-28-ursolic acid (6), emodin (7), gallic acid (8), monotropein (9), adenosine (10).
  
  
  CONCLUSIONS
  Compounds 2,4,6,7,10 were obtained from this genus for the first time, compounds 5, 9 were obtained from this species for the first time. Antifungal activity of compounds 1-4, 6-9 were evaluated. Compound 1 showed the strong activity.
authors.affiliation: School of Pharmaceutical Sciences, Peking University, Beijing 100083, China.
authors.forename: Lei
authors.initials: L
authors.lastname: Liu
authors.forename: Yu-ping
authors.initials: YP
authors.lastname: Chen
authors.forename: Zhe
authors.initials: Z
authors.lastname: Wan
authors.forename: An-liang
authors.initials: AL
authors.lastname: Li
authors.forename: Ruo-yu
authors.initials: RY
authors.lastname: Li
authors.forename: Peng-fei
authors.initials: PF
authors.lastname: Tu
mesh_terms: D000935:Antifungal Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D003455:Cryptococcus neoformans / Q000187:drug effects; D039823:Iridoids / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D009285:Naphthoquinones / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D010946:Plants, Medicinal / Q000737:chemistry; D031828:Pyrola / Q000737:chemistry*; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
chemical_list: D000935:Antifungal Agents; D039823:Iridoids; D009285:Naphthoquinones; D014315:Triterpenes; C507582:monotropein; C057774:chimaphilin; C013330:uvaol