Bacillamides from a hypersaline microbial mat bacterium.
Chemical studies of a Bacillus endophyticus isolated from a Bahamian hypersaline microbial mat led to the isolation of bacillamides B and C, new tryptamide thiazole metabolites. Bioassay-guided fractionation using a HPLC-UV-MS bioassay technique enabled the detection of these trace fermentation products, and their total structures were elucidated by combined spectroscopic techniques.
Socha
Aaron M
AM
Department of Biomedical and Pharmaceutical Sciences, College of Pharmacy, University of Rhode Island, Kingston, Rhode Island 02881, USA.
Long
Richard A
RA
Rowley
David C
DC
D001407:Bacillus / Q000737:chemistry*; D001444:Bahamas; D002851:Chromatography, High Pressure Liquid; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D013844:Thiazoles / Q000737:chemistry / Q000302:isolation & purification*; D014363:Tryptamines / Q000737:chemistry / Q000302:isolation & purification*; D014871:Water Microbiology
D013844:Thiazoles; D014363:Tryptamines; C525339:bacillamide B; C525340:bacillamide C