title: [Chronic relapsing inflammatory optic neuropathy (CRION) without detection of IgG-NMO antibodies].
abstract: Chronic relapsing inflammatory optic neuropathy is a disease that should be distinguished from demyelinating optic neuropathy (ON). Long-term immunosuppressive therapy is usually necessary and either an inflammatory granulomatous origin or a relationship with neuromyelitis optica (NMO) is hypothesized. We report a 43-year-old man who suffered from several ON episodes affecting one eye or the other. These ON attacks completely disappeared with steroid therapy but relapsed after its withdrawal. IgG-NMO antibodies were negative.
authors.affiliation: Servicio de Neurología, Hospitales Universitarios Virgen del Rocío, Sevilla, Spain. hperezdiaz@yahoo.es
authors.forename: H
authors.initials: H
authors.lastname: Pérez-Díaz
authors.forename: J L
authors.initials: JL
authors.lastname: Casado
authors.forename: A
authors.initials: A
authors.lastname: Uclés-Sánchez
authors.forename: A
authors.initials: A
authors.lastname: Saiz
mesh_terms: D000328:Adult; D002908:Chronic Disease; D003937:Diagnosis, Differential; D019084:Fluorescent Antibody Technique, Indirect; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008297:Male; D009471:Neuromyelitis Optica / Q000175:diagnosis / Q000276:immunology; D009902:Optic Neuritis / Q000175:diagnosis / Q000188:drug therapy / Q000276:immunology*; D011241:Prednisone / Q000627:therapeutic use; D012008:Recurrence
chemical_list: D007074:Immunoglobulin G; D007166:Immunosuppressive Agents; D011241:Prednisone