Evaluation of different meshing algorithms in the computation of defibrillation thresholds in children.
In this paper we evaluate different meshing schemes to solve for the bioelectric fields that arise in the human body due to the defibrillation shock generated by an Implantable Cardiac Defibrillator, with particular emphasis on implantation in children. For children, the question of relative performance of different electrode locations remains open. Computational simulation is a critical tool to address this question, and mesh design is a critical component of such simulations. We use the SCIRun software package to address this simulation problem because it combines the powerful numeric tools required with interactive flexibility allowing easy comparison of both algorithms and electrode orientation. We describe a pipeline that starts with segmented CT-images and produces clinically useful parameters. Using this framework we report below that a meshing scheme using regularly spaced hexahedral elements which are locally refined around the electrodes constitute a quick and relatively accurate way of solving this problem.
Stinstra
Jeroen G
JG
Scientific Computing and Imaging Institute, Cardio Vascular Research and Training Institute, University of Utah, Salt Lake City, UT, USA. jeroen@cvrti.utah.edu
Jolley
Matthew
M
Callahan
Michael
M
Weinstein
David
D
Cole
Martin
M
Brooks
Dana H
DH
Triedman
John
J
MacLeod
Rob S
RS
D000465:Algorithms; D003198:Computer Simulation; D004056:Differential Threshold / Q000502:physiology*; D004554:Electric Countershock / Q000379:methods*; D006329:Heart Conduction System / Q000502:physiology*; D006801:Humans; D008955:Models, Cardiovascular; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D012984:Software; D013813:Therapy, Computer-Assisted / Q000379:methods*