title: [A case of octreotide acetate-induced acute pancreatitis].
abstract: A 56-year-old man was admitted to our hospital in July 2000 because of epigastralgia and back pain with past history of repeated upper abdominal pain due to acute pancreatitis since 1995. Abdominal computed tomography on admission showed a swelling in the pancreas head and several large pancreatic pseudocysts. He was diagnosed as acute pancreatitis based on abdominal pain, elevated pancreatic enzymes and computed tomography finding, and given 50 microg octreotide subcutaneously for the treatment of pancreatic pseudocysts. Within 3 hours after octreotide injection, he complained of upper abdominal pain and had an elevated serum amylase level. Abdominal pain disappeared after cessation of octreotide injection and the patient was discharged free from abdominal pain. Octreotide might cause acute pancreatitis by inducing spasm of the sphincter of Oddi. Careful check-up of the patients might be needed during treatment with octreotide.
authors.affiliation: Department of Gastroenterology and Metabolism, University of Occupational and Environmental Health, Japan, School of Medicine.
authors.forename: Kaori
authors.initials: K
authors.lastname: Nagata
authors.forename: Yasuyuki
authors.initials: Y
authors.lastname: Kihara
authors.forename: Ryoji
authors.initials: R
authors.lastname: Eguchi
authors.forename: Hayato
authors.initials: H
authors.lastname: Nakamura
authors.forename: Ichiro
authors.initials: I
authors.lastname: Yoshikawa
authors.forename: Makoto
authors.initials: M
authors.lastname: Otsuki
mesh_terms: D015746:Abdominal Pain / Q000209:etiology; D000208:Acute Disease; D005765:Gastrointestinal Agents / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D015282:Octreotide / Q000009:adverse effects*; D010192:Pancreatic Pseudocyst / Q000188:drug therapy*; D010195:Pancreatitis / Q000139:chemically induced*
chemical_list: D005765:Gastrointestinal Agents; D015282:Octreotide