title: Novel Brønsted acid catalyzed three-component alkylations of indoles with N-phenylselenophthalimide and styrenes.
abstract: Novel and efficient Brønsted acid (p-TsOH) catalyzed inter- and intramolecular Friedel-Crafts alkylations have been developed to synthesize selenated three-component coupling and selenation-cyclization indole derivatives. Chemical removal of the phenylseleno moiety was investigated, and the reaction mechanisms were discussed.
authors.affiliation: Dalian Institute of Chemical Physics, Chinese Academy of Sciences (CAS), 457 Zhongshan Road, Dalian, Liaoning 116023, PR China.
authors.forename: Xiaodan
authors.initials: X
authors.lastname: Zhao
authors.forename: Zhengkun
authors.initials: Z
authors.lastname: Yu
authors.forename: Tongyu
authors.initials: T
authors.lastname: Xu
authors.forename: Ping
authors.initials: P
authors.lastname: Wu
authors.forename: Haifeng
authors.initials: H
authors.lastname: Yu
mesh_terms: D000143:Acids / Q000737:chemistry*; D000478:Alkylation; D002384:Catalysis; D018360:Crystallography, X-Ray; D007211:Indoles / Q000138:chemical synthesis* / Q000737:chemistry; D008958:Models, Molecular; D015394:Molecular Structure; D010636:Phenols / Q000737:chemistry*; D010797:Phthalimides / Q000737:chemistry*; D018036:Selenium Compounds / Q000737:chemistry*; D013343:Styrenes / Q000737:chemistry*
chemical_list: D000143:Acids; D007211:Indoles; D010636:Phenols; D010797:Phthalimides; D018036:Selenium Compounds; D013343:Styrenes; C030374:indole