Volume mesh generation and finite element analysis of trabecular bone magnetic resonance images.
In order to help the assessment of trabecular bone diseases and complement Dual X-Ray Absorptiometry (DXA) in diagnosis process, it is needed an accurate mechanical characterization of trabecular bone structure to estimate the risk of fracture and evaluate micro-architecture deterioration. As Finite Element modeling has become a well-established method for analysis of complex structures, an algorithm has been developed to build a Finite Element mesh from three-dimensional reconstruction information in voxels. Generated mesh is loaded in a Finite Element analysis software in order to simulate micro-architecture mechanical behavior under compression conditions. Most part of related researches have been based on ex vivo micro-Computed Tomography (microCT) scans. This study uses three-dimensional trabecular bone reconstructions from high resolution Magnetic Resonance images acquired in vivo.
Alberich-Bayarri
Angel
A
Biomedical Synergy, Universitat Politècnica de València, 46730 Gandia, Valencia, Spain.
Moratal
David
D
Martí-Bonmatí
Luis
L
Salmerón-Sánchez
Manuel
M
Vallés-Lluch
Ana
A
Nieto-Charques
Laura
L
Rieta
José J
JJ
D000465:Algorithms; D000818:Animals; D001842:Bone and Bones / Q000166:cytology* / Q000502:physiology*; D003198:Computer Simulation; D004548:Elasticity; D020342:Finite Element Analysis; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D021621:Imaging, Three-Dimensional / Q000379:methods*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008954:Models, Biological; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013314:Stress, Mechanical