title: Effectiveness of a triclosan/copolymer dentifrice on dental plaque and gingivitis in Brazilian individuals with cerebral palsy.
abstract: This randomized clinical trial investigated the effect of a dentifrice containing triclosan on the reduction of dental plaque and gingivitis in institutionalized individuals with cerebral palsy. Fifty-seven residents were randomly allocated to a test group (n=28, dentifrice with triclosan) and a control group (n=29, conventional dentifrice). A single calibrated investigator performed examinations at baseline and after three months. The amount of dental plaque was assessed, and gingivitis was measured. The caretakers performed brushing with dentifrice. After three months, there was a significant reduction in the plaque index in both groups, but there was no difference between the two groups. There was a significant reduction in gingivitis only in the test group, and the difference between groups was significant after three months. The authors concluded that the dentifrice with triclosan reduced interdental bleeding in the studied population.
authors.affiliation: University of São Paulo, Brazil.
authors.forename: Hsu Shao
authors.initials: HS
authors.lastname: Feng
authors.forename: Isabella Cristina Mendes
authors.initials: IC
authors.lastname: Pinheiro
authors.forename: Sabrina Rosa
authors.initials: SR
authors.lastname: Grande
authors.forename: Cláudio Mendes
authors.initials: CM
authors.lastname: Pannuti
authors.forename: Fernando José Nunes
authors.initials: FJ
authors.lastname: Barros
authors.forename: Roberto Fraga Moreira
authors.initials: RF
authors.lastname: Lotufo
mesh_terms: D000328:Adult; D002547:Cerebral Palsy / Q000150:complications*; D003730:Dental Care for Persons with Disabilities; D003773:Dental Plaque / Q000150:complications / Q000517:prevention & control*; D003774:Dental Plaque Index; D003802:Dentifrices / Q000627:therapeutic use*; D004311:Double-Blind Method; D004338:Drug Combinations; D005260:Female; D005459:Fluorides / Q000627:therapeutic use; D005891:Gingivitis / Q000150:complications / Q000517:prevention & control*; D006801:Humans; D008297:Male; D010512:Periodontal Index; D018709:Statistics, Nonparametric; D014260:Triclosan / Q000627:therapeutic use*
chemical_list: D003802:Dentifrices; D004338:Drug Combinations; D014260:Triclosan; D005459:Fluorides