title: Genomic approaches in genetic research for endocrine diseases.
abstract: Genomic research has made great progress to understanding functional roles in noncoding DNA sequences. In particular, approaches to identify regulatory elements with enhancer/silencer function based on the synergism between computational and experimental techniques are discussed. Such approaches have been applied to gene-directed as well as genome-wide investigations.
authors.affiliation: Laboratory of Molecular Genetics, G. Gaslini Institute, and Department of Pediatrics and CEBR, University of Genova, Genova, Italy.
authors.forename: Roberto
authors.initials: R
authors.lastname: Ravazzolo
mesh_terms: D000818:Animals; D002843:Chromatin / Q000378:metabolism / Q000502:physiology; D003094:Collagen / Q000235:genetics; D024042:Collagen Type I; D004700:Endocrine System Diseases / Q000235:genetics*; D023281:Genomics / Q000379:methods*; D006801:Humans; D008954:Models, Biological
chemical_list: D002843:Chromatin; D024042:Collagen Type I; D003094:Collagen