title: Phosphoryl azides as versatile new reaction partners in the Cu-catalyzed three-component couplings.
abstract: Phosphoryl azide was successfully employed as an efficient reacting partner in the Cu-catalyzed three-component reaction with 1-alkynes and amines to produce the corresponding phosphoryl amidines in high yields. A range of fruitful applicability of the produced amidines was also demonstrated such as an alkoxide exchange and asymmetric alpha-alkylation of optically active BINOL-derived amidines.
authors.affiliation: Center for Molecular Design and Synthesis, Department of Chemistry and School of Molecular Science (BK21), Korea Advanced Institute of Science and Technology, Daejeon 305-701, Republic of Korea.
authors.forename: Seok Hwan
authors.initials: SH
authors.lastname: Kim
authors.forename: Doo Young
authors.initials: DY
authors.lastname: Jung
authors.forename: Sukbok
authors.initials: S
authors.lastname: Chang