A novel triterpene from Centella asiatica.
A novel triterpene, 2alpha,3beta,20,23-tetrahydroxyurs-28-oic acid (1), was isolated from the aerial part of Centella asiatica. Its structure was elucidated by spectroscopic methods, including 2D-NMR spectra. It displayed no activity against Hela and A549 cell lines at concentrations of 10 and 30 microg/mL, respectively.
Yu
Quan-Lin
QL
College of Pharmaceutical Sciences and Biotechnology, Tianjin University, Tianjin 300072, PR China. quanlin_yu@yahoo.com.cn
Duan
Hong-Quan
HQ
Takaishi
Yoshihisa
Y
Gao
Wen-Yuan
WY
D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000494:pharmacology; D028041:Centella / Q000737:chemistry*; D005260:Female; D006367:HeLa Cells; D006801:Humans; D008175:Lung Neoplasms / Q000188:drug therapy; D009682:Magnetic Resonance Spectroscopy; D014315:Triterpenes / Q000737:chemistry* / Q000494:pharmacology; D002583:Uterine Cervical Neoplasms / Q000188:drug therapy
D000972:Antineoplastic Agents, Phytogenic; D014315:Triterpenes