title: Efficacy of lifestyle change psychological intervention in coronary risk reduction.
abstract: OBJECTIVE
  To evaluate the efficacy of a program of lifestyle change through psychological intervention, combined with pharmacological therapy, for coronary risk reduction in uncontrolled hypertensive patients with overweight and dyslipidemia over 11 months of follow-up.
  
  
  METHODS
  A randomized controlled trial with 74 patients assigned to three different treatment programs. One group (CT) only received conventional pharmacological treatment. Another group (OG) received pharmacological treatment and participated in a guidance program to control cardiovascular risk factors. A third group (LSPI) received pharmacological treatment and participated in a brief psychological intervention program for reduction of estresse levels and changing of eating behavior. The main measure was the Framingham risk index.
  
  
  RESULTS
  CT patients presented an average reduction of 18% (p = 0.001) in coronary risk; OG patients elevated the risk by 0.8% (NS) and the LSPI group showed an average reduction of 27% on the Framingham risk index (p = 0.001).
  
  
  CONCLUSIONS
  Pharmacological treatment combined with psychological intervention for reduction of estresse level and changing of eating behavior resulted in additional benefits in coronary risk reduction.
authors.affiliation: Clínica de Hipertensão e Diabetes, Hospital do Rim e Hipertensão, UNIFESP, São Paulo, SP, Brasil. rita@menorrisco.com.br
authors.forename: Rita
authors.initials: R
authors.lastname: Pugliese
authors.forename: Maria Tereza
authors.initials: MT
authors.lastname: Zanella
authors.forename: Sérgio Luís
authors.initials: SL
authors.lastname: Blay
authors.forename: Frida
authors.initials: F
authors.lastname: Plavinik
authors.forename: Marco Antonio
authors.initials: MA
authors.lastname: Andrade
authors.forename: Roberto
authors.initials: R
authors.lastname: Galvão
mesh_terms: D000328:Adult; D001521:Behavior Therapy / Q000592:standards*; D001786:Blood Glucose; D001794:Blood Pressure / Q000502:physiology; D015992:Body Mass Index; D002784:Cholesterol / Q000097:blood; D003376:Counseling; D050171:Dyslipidemias / Q000628:therapy*; D004812:Epidemiologic Methods; D005247:Feeding Behavior / Q000523:psychology; D005260:Female; D006801:Humans; D006973:Hypertension / Q000188:drug therapy / Q000628:therapy*; D008019:Life Style; D008297:Male; D008875:Middle Aged; D009043:Motor Activity; D017063:Outcome Assessment, Health Care; D050177:Overweight / Q000628:therapy*; D040242:Risk Reduction Behavior; D013312:Stress, Physiological / Q000523:psychology / Q000628:therapy; D014280:Triglycerides / Q000097:blood
chemical_list: D001786:Blood Glucose; D014280:Triglycerides; D002784:Cholesterol