Successful treatment of retroperitoneal giant cell-type malignant fibrous histiocytoma in a 5-year-old boy.
Malignant fibrous histiocytoma, usually seen in patients older than 10 years, is an aggressive soft-tissue sarcoma occurring mostly in the extremities and the trunk, but it is extremely rare in children. We report the clinical, radiological and pathologic features of a five-year-old boy who was diagnosed as a retroperitoneally originated malignant fibrous histiocytoma. The patient with unresectable mass was successfully treated with multidisciplinary approach, with chemotherapy, surgery and radiotherapy, by using combined chemotherapy consisting of vincristine, cisplatinum, adriamycin, cyclophosphamide, actinomycin D and dacarbazine.
Cağlar
Kudret
K
Department of Pediatrics, Dr. Burhan Nalbantoğlu State Hospital, Nicosia, North Cyprus.
Güngör
Sabiha
S
Akansoy
Sezin
S
Sakalli
Umit
U
Orhan
Diclehan
D
Cağlar
Melda
M
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002675:Child, Preschool; D003131:Combined Modality Therapy; D051677:Histiocytoma, Malignant Fibrous / Q000175:diagnosis / Q000473:pathology / Q000628:therapy*; D006801:Humans; D008297:Male; D012186:Retroperitoneal Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000628:therapy*; D014057:Tomography, X-Ray Computed