Gene Ontology annotations at SGD: new data sources and annotation methods.
The Saccharomyces Genome Database (SGD; http://www.yeastgenome.org/) collects and organizes biological information about the chromosomal features and gene products of the budding yeast Saccharomyces cerevisiae. Although published data from traditional experimental methods are the primary sources of evidence supporting Gene Ontology (GO) annotations for a gene product, high-throughput experiments and computational predictions can also provide valuable insights in the absence of an extensive body of literature. Therefore, GO annotations available at SGD now include high-throughput data as well as computational predictions provided by the GO Annotation Project (GOA UniProt; http://www.ebi.ac.uk/GOA/). Because the annotation method used to assign GO annotations varies by data source, GO resources at SGD have been modified to distinguish data sources and annotation methods. In addition to providing information for genes that have not been experimentally characterized, GO annotations from independent sources can be compared to those made by SGD to help keep the literature-based GO annotations current.
Hong
Eurie L
EL
Department of Genetics, Stanford University, Stanford, CA, USA.
Balakrishnan
Rama
R
Dong
Qing
Q
Christie
Karen R
KR
Park
Julie
J
Binkley
Gail
G
Costanzo
Maria C
MC
Dwight
Selina S
SS
Engel
Stacia R
SR
Fisk
Dianna G
DG
Hirschman
Jodi E
JE
Hitz
Benjamin C
BC
Krieger
Cynthia J
CJ
Livstone
Michael S
MS
Miyasato
Stuart R
SR
Nash
Robert S
RS
Oughtred
Rose
R
Skrzypek
Marek S
MS
Weng
Shuai
S
Wong
Edith D
ED
Zhu
Kathy K
KK
Dolinski
Kara
K
Botstein
David
D
Cherry
J Michael
JM
D019295:Computational Biology; D030541:Databases, Genetic; D005800:Genes, Fungal; D016681:Genome, Fungal; D023281:Genomics; D020407:Internet; D012441:Saccharomyces cerevisiae / Q000235:genetics*; D029701:Saccharomyces cerevisiae Proteins / Q000737:chemistry / Q000235:genetics* / Q000502:physiology; D014584:User-Computer Interface; D018875:Vocabulary, Controlled
D029701:Saccharomyces cerevisiae Proteins