title: Focal cholesterol granuloma in the anterior mediastinum: [18F]-fluoro-2-deoxy-D-glucose-positron emission tomography and magnetic resonance imaging findings.
abstract: Cholesterol granuloma is a foreign-body type granuloma that forms in reaction to cholesterol crystals. We report a rare case of focal cholesterol granuloma in the anterior mediastinum of a 62-year-old asymptomatic man that presented as an indeterminate anterior mediastinal nodule on [18F]-fluoro-2-deoxy-D-glucose-positron emission tomography and computed tomography scans. T1- and T2-weighted magnetic resonance images revealed markedly hypo-intense signals reflecting pathologic hyalinized collagen fibers. Magnetic resonance signal characteristics might be helpful for distinguishing benign cholesterol granulomas from malignant neoplasms.
authors.affiliation: Department of Radiology, Kurume University School of Medicine, Fukuoka, Japan. kimichan@med.kurume-u.ac.jp
authors.forename: Kiminori
authors.initials: K
authors.lastname: Fujimoto
authors.forename: Shinzo
authors.initials: S
authors.lastname: Takamori
authors.forename: Hirohisa
authors.initials: H
authors.lastname: Yano
authors.forename: Junko
authors.initials: J
authors.lastname: Sadohara
authors.forename: Toshihiro
authors.initials: T
authors.lastname: Matsuo
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Terazaki
authors.forename: Masatoshi
authors.initials: M
authors.lastname: Ishibashi
authors.forename: Naofumi
authors.initials: N
authors.lastname: Hayabuchi
mesh_terms: D002784:Cholesterol / Q000378:metabolism*; D019788:Fluorodeoxyglucose F18; D006099:Granuloma / Q000000981:diagnostic imaging*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008482:Mediastinum / Q000000981:diagnostic imaging*; D008875:Middle Aged; D049268:Positron-Emission Tomography; D019275:Radiopharmaceuticals
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18; D002784:Cholesterol