title: Enteropathogen Resource Integration Center (ERIC): bioinformatics support for research on biodefense-relevant enterobacteria.
abstract: ERIC, the Enteropathogen Resource Integration Center (www.ericbrc.org), is a new web portal serving as a rich source of information about enterobacteria on the NIAID established list of Select Agents related to biodefense-diarrheagenic Escherichia coli, Shigella spp., Salmonella spp., Yersinia enterocolitica and Yersinia pestis. More than 30 genomes have been completely sequenced, many more exist in draft form and additional projects are underway. These organisms are increasingly the focus of studies using high-throughput experimental technologies and computational approaches. This wealth of data provides unprecedented opportunities for understanding the workings of basic biological systems and discovery of novel targets for development of vaccines, diagnostics and therapeutics. ERIC brings information together from disparate sources and supports data comparison across different organisms, analysis of varying data types and visualization of analyses in human and computer-readable formats.
authors.affiliation: Genome Center, University of Wisconsin, 425G Henry Mall, Madison, Madison, WI 53703, USA. jglasner@wisc.edu
authors.forename: Jeremy D
authors.initials: JD
authors.lastname: Glasner
authors.forename: Guy
authors.initials: G
authors.lastname: Plunkett
authors.forename: Bradley D
authors.initials: BD
authors.lastname: Anderson
authors.forename: David J
authors.initials: DJ
authors.lastname: Baumler
authors.forename: Bryan S
authors.initials: BS
authors.lastname: Biehl
authors.forename: Valerie
authors.initials: V
authors.lastname: Burland
authors.forename: Eric L
authors.initials: EL
authors.lastname: Cabot
authors.forename: Aaron E
authors.initials: AE
authors.lastname: Darling
authors.forename: Bob
authors.initials: B
authors.lastname: Mau
authors.forename: Eric C
authors.initials: EC
authors.lastname: Neeno-Eckwall
authors.forename: David
authors.initials: D
authors.lastname: Pot
authors.forename: Yu
authors.initials: Y
authors.lastname: Qiu
authors.forename: Anna I
authors.initials: AI
authors.lastname: Rissman
authors.forename: Sara
authors.initials: S
authors.lastname: Worzella
authors.forename: Sam
authors.initials: S
authors.lastname: Zaremba
authors.forename: Joel
authors.initials: J
authors.lastname: Fedorko
authors.forename: Tom
authors.initials: T
authors.lastname: Hampton
authors.forename: Paul
authors.initials: P
authors.lastname: Liss
authors.forename: Michael
authors.initials: M
authors.lastname: Rusch
authors.forename: Matthew
authors.initials: M
authors.lastname: Shaker
authors.forename: Lorie
authors.initials: L
authors.lastname: Shaull
authors.forename: Panna
authors.initials: P
authors.lastname: Shetty
authors.forename: Silpa
authors.initials: S
authors.lastname: Thotakura
authors.forename: Jon
authors.initials: J
authors.lastname: Whitmore
authors.forename: Frederick R
authors.initials: FR
authors.lastname: Blattner
authors.forename: John M
authors.initials: JM
authors.lastname: Greene
authors.forename: Nicole T
authors.initials: NT
authors.lastname: Perna
mesh_terms: D001426:Bacterial Proteins / Q000737:chemistry / Q000145:classification / Q000235:genetics; D035843:Biomedical Research; D023482:Bioterrorism; D019295:Computational Biology; D004251:DNA Transposable Elements; D030541:Databases, Genetic; D004755:Enterobacteriaceae / Q000235:genetics*; D004756:Enterobacteriaceae Infections / Q000175:diagnosis / Q000517:prevention & control / Q000628:therapy; D016680:Genome, Bacterial; D023281:Genomics; D020407:Internet; D020411:Oligonucleotide Array Sequence Analysis; D040901:Proteomics; D016415:Sequence Alignment; D012984:Software; D018511:Systems Integration
chemical_list: D001426:Bacterial Proteins; D004251:DNA Transposable Elements