title: Cervical human papillomavirus (HPV) infection in South African women: implications for HPV screening and vaccine strategies.
abstract: The prevalence of cervical human papillomavirus (HPV) in South African women (n = 1,073) increased from 20.4% (173/848) in women with normal cytology to 41.7% (48/115) in women with atypical squamous cells of undetermined significance, 70.2% (40/57) in women with low-grade squamous intraepithelial lesions, and 83% (44/53) in women with high-grade squamous intraepithelial lesions (HSILs). HPV types 16 and 35 were the dominant types in women with HSILs but not in women in the other categories.
authors.affiliation: Institute of Infectious Disease and Molecular Medicine and Division of Medical Virology, Department of Clinical Laboratory Sciences, Faculty of Health Sciences, University of Cape Town, Observatory, Cape Town, South Africa.
authors.forename: Bruce
authors.initials: B
authors.lastname: Allan
authors.forename: Dianne J
authors.initials: DJ
authors.lastname: Marais
authors.forename: Margaret
authors.initials: M
authors.lastname: Hoffman
authors.forename: Samuel
authors.initials: S
authors.lastname: Shapiro
authors.forename: Anna-Lise
authors.initials: AL
authors.lastname: Williamson
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D008875:Middle Aged; D010212:Papilloma / Q000453:epidemiology / Q000821:virology; D027383:Papillomaviridae / Q000145:classification* / Q000302:isolation & purification*; D030361:Papillomavirus Infections / Q000453:epidemiology* / Q000473:pathology / Q000821:virology*; D011230:Precancerous Conditions / Q000453:epidemiology / Q000821:virology; D015995:Prevalence; D013019:South Africa / Q000453:epidemiology; D002577:Uterine Cervical Diseases / Q000453:epidemiology* / Q000473:pathology / Q000821:virology*