title: Primary cutaneous meningioma of the scalp: a case report and review of literature.
abstract: Meningiomas of the skin are rare tumors that can pose considerable diagnostic challenges to the pathologist. This study presents a case of primary cutaneous meningioma in a newly born baby girl that presents with a subcutaneous nodule on the left posterior occipital scalp. A Magnetic Resonance Imaging examination failed to detect any communication between the tumor site and the meninges. The mass was excised and intra -operatively, there was no evidence of connection between the tumor and the underlying tissues. Microscopically, the tumor was composed of banal looking, mitotically inactive spindle-shaped cells with a whorled configuration. Some cells were concentrically arranged around blood vessels. Immunohistochemical studies were positive for epithelial membrane antigen and vimentin. Immunostains for cytokeratin, S-100 protein, vascular (CD34 and CD31) and muscle markers (Desmin and smooth muscle actin) were negative. The diagnosis of cutaneous meningioma was established. A review of literature was presented.
authors.affiliation: Department of Pathology, Faculty of Medicine, Assuit University Hospitals, Egypt. mrh17@swissinfo.org
authors.forename: Mahmoud R
authors.initials: MR
authors.lastname: Hussein
authors.forename: Ahmed Rezk
authors.initials: AR
authors.lastname: Abdelwahed
mesh_terms: D014408:Biomarkers, Tumor / Q000032:analysis; D001706:Biopsy; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008279:Magnetic Resonance Imaging; D008579:Meningioma / Q000737:chemistry / Q000151:congenital / Q000473:pathology* / Q000601:surgery; D018396:Mucin-1 / Q000032:analysis; D012878:Skin Neoplasms / Q000737:chemistry / Q000151:congenital / Q000473:pathology* / Q000601:surgery; D016896:Treatment Outcome; D014746:Vimentin / Q000032:analysis
chemical_list: D014408:Biomarkers, Tumor; D018396:Mucin-1; D014746:Vimentin