title: Spirastrellolides C to G: macrolides obtained from the marine sponge Spirastrella coccinea.
abstract: Five new macrolides, spirastrellolides C (3) to G (7), have been isolated from extracts of the marine sponge Spirastrella coccinea collected in Dominica. Their structures have been elucidated by a combination of spectroscopic analysis and chemical transformations.
authors.affiliation: Departments of Chemistry and Earth & Ocean Sciences, University of British Columbia, Vancouver, B.C., Canada V6T 1Z1.
authors.forename: David E
authors.initials: DE
authors.lastname: Williams
authors.forename: Robert A
authors.initials: RA
authors.lastname: Keyzers
authors.forename: Kaoru
authors.initials: K
authors.lastname: Warabi
authors.forename: Kelsey
authors.initials: K
authors.lastname: Desjardine
authors.forename: Jenna L
authors.initials: JL
authors.lastname: Riffell
authors.forename: Michel
authors.initials: M
authors.lastname: Roberge
authors.forename: Raymond J
authors.initials: RJ
authors.lastname: Andersen
mesh_terms: D000818:Animals; D004791:Enzyme Inhibitors / Q000737:chemistry* / Q000302:isolation & purification; D018942:Macrolides / Q000737:chemistry* / Q000302:isolation & purification; D009682:Magnetic Resonance Spectroscopy / Q000379:methods / Q000592:standards; D008968:Molecular Conformation; D011161:Porifera / Q000737:chemistry*; D012015:Reference Standards; D013237:Stereoisomerism
chemical_list: D004791:Enzyme Inhibitors; D018942:Macrolides; C526566:spirastrellolide C; C526567:spirastrellolide G