title: Electrochemical detection coupled with high-performance liquid chromatography in pharmaceutical and biomedical analysis: a mini review.
abstract: Recent advances in electrochemical detection techniques coupled with high-performance liquid chromatography (HPLC-ECD) in pharmaceutical and biomedical analysis are reviewed. ECD classification and modes including common amperometric, coulometric, conductimetric, and potentiometric detector, are outlined and the some typical examples of determinations in pharmaceutical and biomedical analysis are described. The electrochemical detection system can offer superior merits over other detectors commonly used with HPLC. These techniques have great potential owing to their prominent characteristics in high-throughput screening procedures of drugs in various matrices. Fundamental 67 references from last 5 years related with a field are cited in this review.
authors.affiliation: College of Chemistry and Chemical Engineering, Yangzhou University, Yangzhou, China.
authors.forename: Chengyin
authors.initials: C
authors.lastname: Wang
authors.forename: Jianyun
authors.initials: J
authors.lastname: Xu
authors.forename: Guiyou
authors.initials: G
authors.lastname: Zhou
authors.forename: Qishu
authors.initials: Q
authors.lastname: Qu
authors.forename: Gongjun
authors.initials: G
authors.lastname: Yang
authors.forename: Xiaoya
authors.initials: X
authors.lastname: Hu
mesh_terms: D002851:Chromatography, High Pressure Liquid / Q000379:methods; D004563:Electrochemistry; D004566:Electrodes; D046210:Microfluidic Analytical Techniques / Q000379:methods; D004364:Pharmaceutical Preparations / Q000032:analysis*
chemical_list: D004364:Pharmaceutical Preparations