Goodpasture's disease in pregnancy: case report and review of the literature.
Goodpasture's disease is a rare phenomenon in pregnancy. It is characterized by antiglomerular basement membrane antibodies resulting in glomerulonephritis and pulmonary hemorrhage. We present a case of a patient with a preconceptional diagnosis of Goodpasture's disease and chronic hypertension. Multidisciplinary antepartum care included close monitoring and treatment of blood pressure, renal function, and fetal status. Our patient ultimately was delivered at 33 weeks for superimposed preeclampsia but recovered without incident. Her infant also did well after 36 days in the neonatal intensive care unit, requiring only supportive care. This case demonstrates that successful pregnancy outcomes can be achieved in patients with Goodpasture's disease with a careful multidisciplinary approach involving maternal fetal medicine and nephrology.
Hatfield
Tamera
T
Department of Obstetrics and Gynecology, University of California, Irvine, Orange, California 92868, USA.
Steiger
Ralph
R
Wing
Deborah A
DA
D000328:Adult; D019867:Anti-Glomerular Basement Membrane Disease / Q000150:complications*; D000959:Antihypertensive Agents / Q000627:therapeutic use; D005260:Female; D006801:Humans; D006973:Hypertension / Q000188:drug therapy / Q000209:etiology; D007741:Labetalol / Q000627:therapeutic use; D007751:Labor, Induced; D011247:Pregnancy; D011248:Pregnancy Complications; D011256:Pregnancy Outcome
D000959:Antihypertensive Agents; D007741:Labetalol