Hyperhidrosis due to deep brain stimulation in a patient with essential tremor. Case report.
The authors present a unique case of hyperhidrosis as a side effect of a misplaced deep brain stimulation (DBS) electrode near the ventrointermedius (Vim) nucleus in a patient with essential tremor. Magnetic resonance imaging of the brain showed electrode placement in the left anterior thalamus traversing the hypothalamus. High-frequency electrical stimulation possibly resulted in unilateral activation of the efferent sympathetic pathways in the zona incerta. Although a rare complication, hypothalamic dysfunction may occur as a stimulation-related side effect of Vim-DBS.
Diamond
Alan
A
Parkinson's Disease Center and Movement Disorders Clinic, Department of Neurology, Baylor College of Medicine, Houston, Texas 77030, USA.
Kenney
Christopher
C
Almaguer
Michael
M
Jankovic
Joseph
J
D000368:Aged; D001933:Brain Stem / Q000503:physiopathology; D046690:Deep Brain Stimulation / Q000009:adverse effects*; D020329:Essential Tremor / Q000628:therapy*; D006801:Humans; D006945:Hyperhidrosis / Q000209:etiology*; D008297:Male; D013564:Sympathetic Nervous System / Q000503:physiopathology