title: A case of primary Hodgkin's lymphoma of the parotid gland.
abstract: We report an extremely rare case (sixth reported case) of primary Hodgkin's lymphoma (HL) (mixed cellularity type) of the parotid gland. A 14-year-old man was referred to our hospital for evaluation of a parotid mass. Although the initial aspiration cytology was highly suggestive of HL, the confirmatory diagnosis obtained by open biopsy was non-specific lymphadenitis. Consequently, the patient was observed without any additional treatment. Because the mass continued to increase in size, we performed a total parotidectomy which led to the diagnosis of mixed cellularity HL. This case suggests that the specimen taken during open biopsy may have been too small (about 1 cm3) to detect the presence of Reed-Sternberg giant cells, which is essential for the diagnosis of HL. Therefore, although primary HL of the parotid gland is extremely rare, adequate tissue sampling of a clinically suspicious parotid mass will be required for the diagnosis of HL.
authors.affiliation: Department of Otorhinolaryngology, Kyushu Koseinenkin Hospital, 2-1-1 Kishinoura, Nishiku, Kitakyushu, Japan. muneyuki.masuda@qkn-hosp.jp
authors.forename: Muneyuki
authors.initials: M
authors.lastname: Masuda
authors.forename: Yuichi
authors.initials: Y
authors.lastname: Segawa
authors.forename: Andrew K
authors.initials: AK
authors.lastname: Joe
authors.forename: Naoya
authors.initials: N
authors.lastname: Hirakawa
authors.forename: Shizuo
authors.initials: S
authors.lastname: Komune
mesh_terms: D000293:Adolescent; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D044963:Biopsy, Fine-Needle; D017024:Chemotherapy, Adjuvant; D003937:Diagnosis, Differential; D006689:Hodgkin Disease / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology / Q000601:surgery; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009367:Neoplasm Staging; D010306:Parotid Gland / Q000473:pathology / Q000601:surgery; D010307:Parotid Neoplasms / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology / Q000601:surgery; D018714:Radiotherapy, Adjuvant; D014057:Tomography, X-Ray Computed