New C-deoxyhexosyl flavones and antioxidant properties of Passiflora edulis leaf extract.
The flavonoids present in passion fruit (Passiflora edulis) leaves were identified by a high-performance liquid chromatography-diode array detection-tandem mass spectrometry (HPLC-DAD-MS/MS) method. Sixteen apigenin or luteolin derivatives were characterized, which included four mono-C-glycosyl, eight O-glycosyl- C-glycosyl, and four O-glycosyl derivatives. With the exceptions of C-hexosyl luteolin and C-hexosyl apigenin, all the compounds exhibited a deoxyhexose moiety. Moreover, the uncommon C-deoxyhexosyl derivatives of luteolin and apigenin have been identified for first time in P. edulis by HPLC-DAD-MS/MS. The antioxidative capacity of passion fruit leaves was checked against DPPH radical and several reactive oxygen species (superoxide radical, hydroxyl radical, and hypochlorous acid), revealing it to be concentration-dependent, although a pro-oxidant effect was noticed for hydroxyl radical.
Ferreres
Federico
F
Research Group on Quality, Safety and Bioactivity of Plant Foods, Department of Food Science and Technology, CEBAS (CSIC), P.O. Box 164, 30100 Campus Univ. Espinardo, Murcia, Spain. federico@cebas.csic.es
Sousa
Carla
C
Valentão
Patrícia
P
Andrade
Paula B
PB
Seabra
Rosa M
RM
Gil-Izquierdo
Angel
A
D000975:Antioxidants / Q000032:analysis* / Q000494:pharmacology; D047310:Apigenin / Q000032:analysis / Q000737:chemistry; D002851:Chromatography, High Pressure Liquid; D047309:Flavones / Q000032:analysis* / Q000737:chemistry / Q000494:pharmacology; D006031:Glycosylation; D047311:Luteolin / Q000032:analysis / Q000737:chemistry; D029598:Passiflora / Q000737:chemistry*; D018515:Plant Leaves / Q000737:chemistry*; D053719:Tandem Mass Spectrometry
D000975:Antioxidants; D047309:Flavones; D047310:Apigenin; D047311:Luteolin