DNA microarrays and their use in dermatology.
Multiple different DNA microarray technologies are available on the market today. They can be used for studying either DNA or RNA with the purpose of identifying and explaining the role of genes involved in different processes. This paper reviews different DNA microarray platforms available for such studies and their usage in cases of malignant melanomas, psoriasis, and exposure of keratinocytes and melanocytes to UV illumination.
Mlakar
Vid
V
Department for molecular genetics, Institute of Pathology, Faculty of Medicine, University of Ljubljana, Zaloska 4, 1000 Ljubljana, Slovenia.
Glavac
Damjan
D
D015870:Gene Expression; D020869:Gene Expression Profiling / Q000379:methods; D006801:Humans; D015603:Keratinocytes / Q000378:metabolism / Q000528:radiation effects*; D008544:Melanocytes / Q000378:metabolism / Q000528:radiation effects*; D008545:Melanoma / Q000235:genetics*; D020411:Oligonucleotide Array Sequence Analysis / Q000379:methods; D011565:Psoriasis / Q000235:genetics*; D014466:Ultraviolet Rays