ZD6474 reverses multidrug resistance by directly inhibiting the function of P-glycoprotein.
Freshney
R I
RI
D020168:ATP Binding Cassette Transporter, Subfamily B, Member 1 / Q000037:antagonists & inhibitors*; D045744:Cell Line, Tumor; D018432:Drug Resistance, Multiple / Q000187:drug effects*; D006801:Humans; D010880:Piperidines / Q000494:pharmacology*; D011799:Quinazolines / Q000494:pharmacology*
D020168:ATP Binding Cassette Transporter, Subfamily B, Member 1; D010880:Piperidines; D011799:Quinazolines; C452423:vandetanib