title: Occupational exposure to volatile organic compounds and aldehydes in the U.S. trucking industry.
abstract: Diesel exhaust is a complex chemical mixture that has been linked to lung cancer mortality in a number of epidemiologic studies. However, the dose-response relationship remains largely undefined, and the specific components responsible for carcinogenicity have not been identified. Although previous focus has been on the particulate phase, diesel exhaust includes a vapor phase of numerous volatile organic compounds (VOCs) and aldehydes that are either known or suspected carcinogens, such as 1,3-butadiene, benzene, and formaldehyde. However, there are relatively few studies that quantify exposure to VOCs and aldehydes in diesel-heavy and other exhaust-related microenvironments. As part of a nationwide assessment of exposure to diesel exhaust in the trucking industry, we collected measurements of VOCs and aldehydes at 15 different U.S. trucking terminals and in city truck drivers (with 6 repeat site visits), observing average shift concentrations in truck cabs and at multiple background and work area locations within each terminal. In this paper, we characterize occupational exposure to 18 different VOCs and aldehydes, as well as relationships with particulate mass (elemental carbon in PM < 1 microm and PM2.5) across locations to determine source characteristics. Our results show that occupational exposure to VOCs and aldehydes varies significantly across the different sampling locations within each terminal, with significantly higher exposures noted in the work environments over background levels (p < 0.01). A structural equation model performed well in predicting terminal exposures to VOCs and aldehydes as a function of job, background levels, weather conditions, proximity to a major road, and geographic location (R2 = 0.2-0.4 work area; R2 = 0.5-0.9 background).
authors.affiliation: Department of Environmental Health, Harvard School of Public Health, 401 Park Drive, Boston, Massachusetts 02215, USA. mary.davis@umit.maine.edu
authors.forename: M E
authors.initials: ME
authors.lastname: Davis
authors.forename: A P
authors.initials: AP
authors.lastname: Blicharz
authors.forename: J E
authors.initials: JE
authors.lastname: Hart
authors.forename: F
authors.initials: F
authors.lastname: Laden
authors.forename: E
authors.initials: E
authors.lastname: Garshick
authors.forename: T J
authors.initials: TJ
authors.lastname: Smith
mesh_terms: D000447:Aldehydes / Q000633:toxicity*; D008401:Gas Chromatography-Mass Spectrometry; D007221:Industry; D016273:Occupational Exposure; D009930:Organic Chemicals / Q000633:toxicity*; D014186:Transportation; D014481:United States; D014835:Volatilization
chemical_list: D000447:Aldehydes; D009930:Organic Chemicals