title: Repetitive transcranial magnetic stimulation of human MT+ reduces apparent motion perception.
abstract: We investigated the effects of repetitive transcranial magnetic stimulation (rTMS) over the human cerebral cortex on apparent motion perception. Previous studies have shown that human extrastriate visual area MT+ (V5) processes not only real but also apparent motion. However, the functional relevance of MT+ on long-range apparent motion perception remains unclear. Here, we show direct evidence for the involvement of MT+ in apparent motion perception using rTMS, which is known to temporarily inhibit a localized region in the cerebral cortex. The results showed that apparent motion perception decreased after applying rTMS over MT+, but not after applying rTMS over the control region (inferior temporal gyrus). The decrease in performance caused by applying rTMS to MT+ suggests that MT+ is a causally responsible region for apparent motion perception, and thus, further supports the idea that MT+ plays a major role in the perception of motion.
authors.affiliation: Department of Psychology, Graduate School of Letters, Kyoto University, Yoshida-honmachi, Sakyo, Kyoto 606-8501, Japan. matsuyoshi@psy.mbox.media.kyoto-u.ac.jp
authors.forename: Daisuke
authors.initials: D
authors.lastname: Matsuyoshi
authors.forename: Nobuyuki
authors.initials: N
authors.lastname: Hirose
authors.forename: Tatsuya
authors.initials: T
authors.lastname: Mima
authors.forename: Hidenao
authors.initials: H
authors.lastname: Fukuyama
authors.forename: Naoyuki
authors.initials: N
authors.lastname: Osaka
mesh_terms: D000328:Adult; D001931:Brain Mapping; D004292:Dominance, Cerebral / Q000502:physiology; D005260:Female; D006801:Humans; D008297:Male; D009039:Motion Perception / Q000502:physiology*; D009433:Neural Inhibition / Q000502:physiology; D009483:Neuropsychological Tests; D009778:Occipital Lobe / Q000033:anatomy & histology / Q000502:physiology*; D010468:Perceptual Disorders / Q000209:etiology / Q000503:physiopathology; D010775:Photic Stimulation; D013702:Temporal Lobe / Q000033:anatomy & histology / Q000502:physiology*; D050781:Transcranial Magnetic Stimulation / Q000009:adverse effects*; D014793:Visual Cortex / Q000033:anatomy & histology / Q000502:physiology*; D014795:Visual Pathways / Q000033:anatomy & histology / Q000502:physiology*