[Antimicrobial susceptibility of H pylori strains obtained from Paraguayan patients].
BACKGROUND
Antimicrobial resistance is one of the main obstacles for an effective eradication of H. pylori infection.


OBJECTIVE
To determine the susceptibility of H. pylori strains obtained from gastric biopsies to metronidazole, clarithromycin and amoxicillin.


METHODS
Susceptibility to metronidazole, clarithromycin and amoxicillin was determined using E-test in 46 isolates of H. pylori obtained from gastric biopsies of 54 adult patients.


RESULTS
Thirty three percent of isolates were resistant to metronidazole and 2% were resistant to clarithromycin and amoxicillin. One isolate was resistant to metronidazole and clarithromycin.


CONCLUSIONS
The antimicrobial susceptibility of these strains of H. pylori obtained from Paraguayan patients, may help to decide the initial therapy to eradicate this infection.
Fariña
Norma
N
Departamento de Microbiología, Instituto de Investigaciones en Ciencias de la Salud, Universidad Nacional de Asunción, Paraguay. microbiologia@iics.una.py
Kasamatsu
Elena
E
Samudio
Margarita
M
Morán
Miryam
M
Sanabria
Rosa
R
Laspina
Florentina
F
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000658:Amoxicillin / Q000494:pharmacology; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D017291:Clarithromycin / Q000494:pharmacology; D024901:Drug Resistance, Multiple, Bacterial; D005260:Female; D016481:Helicobacter Infections / Q000382:microbiology*; D016480:Helicobacter pylori / Q000187:drug effects*; D006801:Humans; D008297:Male; D008795:Metronidazole / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D010239:Paraguay
D000900:Anti-Bacterial Agents; D008795:Metronidazole; D000658:Amoxicillin; D017291:Clarithromycin