ProtozoaDB: dynamic visualization and exploration of protozoan genomes.
ProtozoaDB (http://www.biowebdb.org/protozoadb) is being developed to initially host both genomics and post-genomics data from Plasmodium falciparum, Entamoeba histolytica, Trypanosoma brucei, T. cruzi and Leishmania major, but will hopefully host other protozoan species as more genomes are sequenced. It is based on the Genomics Unified Schema and offers a modern Web-based interface for user-friendly data visualization and exploration. This database is not intended to duplicate other similar efforts such as GeneDB, PlasmoDB, TcruziDB or even TDRtargets, but to be complementary by providing further analyses with emphasis on distant similarities (HMM-based) and phylogeny-based annotations including orthology analysis. ProtozoaDB will be progressively linked to the above-mentioned databases, focusing in performing a multi-source dynamic combination of information through advanced interoperable Web tools such as Web services. Also, to provide Web services will allow third-party software to retrieve and use data from ProtozoaDB in automated pipelines (workflows) or other interoperable Web technologies, promoting better information reuse and integration. We also expect ProtozoaDB to catalyze the development of local and regional bioinformatics capabilities (research and training), and therefore promote/enhance scientific advancement in developing countries.
Dávila
Alberto M R
AM
Oswaldo Cruz Institute, FIOCRUZ, CCB, Federal University of Santa Catarina (UFSC), ACBS/UNOESC/SC, COPPE, Federal University of Rio de Janeiro, Brazil. davila@fiocruz.br
Mendes
Pablo N
PN
Wagner
Glauber
G
Tschoeke
Diogo A
DA
Cuadrat
Rafael R C
RR
Liberman
Felipe
F
Matos
Luciana
L
Satake
Thiago
T
Ocaña
Kary A C S
KA
Triana
Omar
O
Cruz
Sérgio M S
SM
Jucá
Henrique C L
HC
Cury
Juliano C
JC
Silva
Fabricio N
FN
Geronimo
Guilherme A
GA
Ruiz
Margarita
M
Ruback
Eduardo
E
Silva
Floriano P
FP
Probst
Christian M
CM
Grisard
Edmundo C
EC
Krieger
Marco A
MA
Goldenberg
Samuel
S
Cavalcanti
Maria C R
MC
Moraes
Milton O
MO
Campos
Maria L M
ML
Mattoso
Marta
M
D000818:Animals; D003196:Computer Graphics; D030541:Databases, Genetic; D004748:Entamoeba histolytica / Q000235:genetics; D018503:Genome, Protozoan; D023281:Genomics; D020407:Internet; D018320:Leishmania major / Q000235:genetics; D010963:Plasmodium falciparum / Q000235:genetics; D015800:Protozoan Proteins / Q000737:chemistry; D012984:Software; D014346:Trypanosoma brucei brucei / Q000235:genetics; D014349:Trypanosoma cruzi / Q000235:genetics; D014584:User-Computer Interface
D015800:Protozoan Proteins