Asymmetric total synthesis of ent-sandaracopimaradiene, a biosynthetic intermediate of oryzalexins.
An asymmetric total synthesis of ent-sandaracopimaradiene, a biosynthetic intermediate of oryzalexins, via B-alkyl Suzuki-Miyaura coupling and Lewis acid-mediated B-ring formation as key steps was achieved.
Yajima
Arata
A
Department of Fermentation Science, Faculty of Applied Biological Science, Tokyo University of Agriculture, Japan. ayaji@nodai.ac.jp
Yamaguchi
Ayumi
A
Nukada
Tomoo
T
Yabuta
Goro
G
D004224:Diterpenes / Q000138:chemical synthesis*; D012717:Sesquiterpenes; D013237:Stereoisomerism; D013729:Terpenes / Q000138:chemical synthesis*; D000094162:Phytoalexins
D004224:Diterpenes; D012717:Sesquiterpenes; D013729:Terpenes; C526354:ent-sandaracopimaradiene; D000094162:Phytoalexins