title: Excitatory components of the mammalian locomotor CPG.
abstract: Locomotion in mammals is to a large degree controlled directly by intrinsic spinal networks, called central pattern generators (CPGs). The overall function of these networks is governed by interaction between inhibitory and excitatory neurons. In the present review, we will discuss recent findings addressing the role of excitatory synaptic transmission for network function including the role of specific excitatory neuronal populations in coordinating muscle activity and in generating rhythmic activity.
authors.affiliation: Mammalian Locomotor Laboratory, Department of Neuroscience, Karolinska Institutet, Retzius väg 8, 171 77 Stockholm, Sweden. O.Kiehn@ki.se
authors.forename: Ole
authors.initials: O
authors.lastname: Kiehn
authors.forename: Katharina A
authors.initials: KA
authors.lastname: Quinlan
authors.forename: Carlos Ernesto
authors.initials: CE
authors.lastname: Restrepo
authors.forename: Line
authors.initials: L
authors.lastname: Lundfald
authors.forename: Lotta
authors.initials: L
authors.lastname: Borgius
authors.forename: Adolfo E
authors.initials: AE
authors.lastname: Talpalar
authors.forename: Toshiaki
authors.initials: T
authors.lastname: Endo
mesh_terms: D000818:Animals; D006801:Humans; D007323:Instinct; D007395:Interneurons / Q000502:physiology; D008124:Locomotion / Q000502:physiology*; D009046:Motor Neurons / Q000502:physiology; D009415:Nerve Net / Q000502:physiology*; D013116:Spinal Cord / Q000502:physiology*; D009435:Synaptic Transmission / Q000502:physiology