title: Clinical evaluation of the effectiveness of enamel matrix proteins and autologous bone graft in the treatment of mandibular Class II furcation defects: a series of 11 patients.
abstract: The purpose of this study was to evaluate the results of treatment of buccal mandibular Class II furcation defects with a combination of autologous bone grafts and enamel matrix derivative over a 24-month period. Eleven individuals with chronic periodontitis were selected and contributed one furcation defect each. Statistically significant improvements in mean vertical probing attachment level and horizontal probing attachment level were obtained at the 2-year evaluation. Complete clinical closure was achieved in four sites, which exhibited favorable defect morphology for this regenerative procedure. All other residual defects were reduced to Class I.
authors.affiliation: Department of Biomedical Sciences and Human Oncology, Section of Periodontology, University of Torino, Italy. mario.aimetti@unito.it
authors.forename: Mario
authors.initials: M
authors.lastname: Aimetti
authors.forename: Federica
authors.initials: F
authors.lastname: Romano
authors.forename: Enrico
authors.initials: E
authors.lastname: Pigella
authors.forename: Matteo
authors.initials: M
authors.lastname: Piemontese
mesh_terms: D053523:Amelogenin / Q000627:therapeutic use*; D001861:Bone Regeneration; D016025:Bone Transplantation; D003746:Dental Enamel Proteins / Q000627:therapeutic use*; D005260:Female; D017823:Furcation Defects / Q000601:surgery*; D006801:Humans; D008297:Male; D008334:Mandible / Q000601:surgery; D008875:Middle Aged; D013524:Surgical Flaps
chemical_list: D053523:Amelogenin; D003746:Dental Enamel Proteins; C109069:enamel matrix proteins