title: [Extended parietal cell vagotomy in the treatment of acute perforation of duodenal ulcer in 176 cases].
abstract: OBJECTIVE
  To evaluate the long-term therapeutic efficacy of extended parietal cell vagotomy (EPCV) in the treatment of duodenal ulcer complicated with acute perforation.
  
  
  METHODS
  Therapeutic efficacy of EPCV in 176 cases subjected to duodenal ulcer with acute perforation since 1979 was evaluated, including postoperative complication, ulcer recurrence rate, gastric empting function, endoscopic and radiographical examination, nutritional status and Visick classification.
  
  
  RESULTS
  Among 176 patients, 153 (86.9%) cases were successfully followed-up for 5 years after operation. No operative death was found. Postprandial superior belly fullness occurred in 13 cases (8.5%) and heartburn in 12 cases (7.8%), which could be relieved by Domperidone. Adhesive ileus was noted in 4 cases (2.6%) which was cured by adhesiolysis. The total ulcer recurrence rate was 2.6% (4 cases) within 2 to 3 years after operation. Superficial gastritis occurred in 21 cases (13.7%) and duodenal bulb in 31 cases (20.3%). Sinus ventriculi vermicular motion was good and gastric emptying was normal. No anemia was found. Body weight gained in 116 cases (75.8%). One hundred and forty-six cases(95.4%) were reforming Visick grade I and II , 3 cases(2.0%) grade III , and 4 cases (2.6%) IV .
  
  
  CONCLUSIONS
  EPCV is convenient for performance with low postoperative complication rate. Its long-term efficacies are quite good, which including normal nutritional status, high quality of life and low ulcer recurrence rate. EPCV is one of effective and safe treatments for duodenal ulcer complicated with acute perforation.
authors.affiliation: Department of General Surgery, General Hospital of Beijing Command of PLA, Center of Military General Surgery, Beijing, China. lsybz@126.com
authors.forename: Shi-Yong
authors.initials: SY
authors.lastname: Li
authors.forename: Zhen-Jia
authors.initials: ZJ
authors.lastname: Liang
authors.forename: Shu-Jun
authors.initials: SJ
authors.lastname: Yuan
authors.forename: Bo
authors.initials: B
authors.lastname: Yu
authors.forename: Gang
authors.initials: G
authors.lastname: Chen
authors.forename: Guang
authors.initials: G
authors.lastname: Chen
authors.forename: Fu-Yi
authors.initials: FY
authors.lastname: Zuo
authors.forename: Xue
authors.initials: X
authors.lastname: Bai
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D004381:Duodenal Ulcer / Q000150:complications / Q000601:surgery*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010439:Peptic Ulcer Perforation / Q000209:etiology / Q000601:surgery*; D016896:Treatment Outcome; D014629:Vagotomy, Proximal Gastric; D055815:Young Adult