title: [Electroconvulsive therapy in therapy-resistant mania. A case study].
abstract: A 25-year-old woman was separated for 6 weeks on account of her suicidal and chaotic behaviour occurring within the framework of a first manic episode. Her response to medication (olanzapine 20 mg, clorazepate 50 mg and lithium (serum level 0.9 mmol/l)) was inadequate. After only one ect treatment her condition had improved to such an extent that she no longer needed to be isolated. After about 4 weeks her mental condition was reasonably good; her medication consisted only of 10 mg of olanzapine and she could be transferred to out-patient care. ect can bring about rapid improvement in patients with therapy-resistant manic symptoms.
authors.affiliation: AMC de Meren, ambulant centrum Nienoord, Nienoord 2, 1112 XG Diemen. m.e.neve@amc.uva.nl
authors.forename: M E C
authors.initials: ME
authors.lastname: Neve
authors.forename: J
authors.initials: J
authors.lastname: Huyser
authors.forename: J H
authors.initials: JH
authors.lastname: Eshuis
authors.forename: J G
authors.initials: JG
authors.lastname: Storosum
mesh_terms: D000328:Adult; D014150:Antipsychotic Agents / Q000627:therapeutic use; D001569:Benzodiazepines / Q000627:therapeutic use; D001714:Bipolar Disorder / Q000188:drug therapy / Q000628:therapy*; D003009:Clorazepate Dipotassium / Q000627:therapeutic use; D004565:Electroconvulsive Therapy / Q000379:methods*; D005260:Female; D006801:Humans; D000077152:Olanzapine; D016896:Treatment Outcome
chemical_list: D014150:Antipsychotic Agents; D001569:Benzodiazepines; D003009:Clorazepate Dipotassium; D000077152:Olanzapine