title: Antidepressant treatment increases quality of life in patients with chronic renal failure.
abstract: To evaluate the effect of citalopram treatment on quality of life (QoL) and depression in 141 patients with chronic renal failure (CRF), QoL was measured by means of the Short Form 36 (SF-36). Patients diagnosed with depression were treated with citalopram for eight weeks and evaluated for the effect of treatment on depressive symptoms and QoL. Thirty-four of 141 patients (24.1%) had depression and treatment with citalopram decreased Beck Depression Inventory Scores and increased the emotional role limitation and the mental health subscale scores of SF-36. This study suggests that citalopram can treat depression and improve QoL in patients with CRF.
authors.affiliation: Division of Nephrology, Faculty of Medicine, University of Kocaeli, Kocaeli, Turkey. bkalender@hotmail.com
authors.forename: Betul
authors.initials: B
authors.lastname: Kalender
authors.forename: Aytul Corapcioglu
authors.initials: AC
authors.lastname: Ozdemir
authors.forename: Irem
authors.initials: I
authors.lastname: Yalug
authors.forename: Erkan
authors.initials: E
authors.lastname: Dervisoglu
mesh_terms: D000328:Adult; D000368:Aged; D000928:Antidepressive Agents / Q000627:therapeutic use*; D015283:Citalopram / Q000627:therapeutic use*; D003863:Depression / Q000188:drug therapy*; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000523:psychology*; D008297:Male; D008875:Middle Aged; D011788:Quality of Life; D006435:Renal Dialysis
chemical_list: D000928:Antidepressive Agents; D015283:Citalopram