title: [Multiple endocrine neoplasia type IIa].
abstract: A gradual manifestation first of parathyroid and then od thyroid and adrenal endocrinopathy in 38-year old female patient, with the syndrome of Multiple Endocrine Neoplasia (MEN) type IIa--Sippl syndrome, is presented. The first diagnosis was hyperparathyroidism, which is unusual in this syndrome, as only a half of the patients affected with MEN IIa have hyperparathyroidism. The diagnosis of medullary thyroid carcinoma is operatively established. The syndrome is diagnosed after the manifestation of the clinical signs of pheochromocytoma. This syndrome is hereditary in autosomal and dominant way. Our patient is the first member in the risk family: the family medical history of our patient was negative. As this syndrome can appear in the age range from 2-67, we intend to make the screening of all the members of the patient's family.
authors.forename: D
authors.initials: D
authors.lastname: Sćepanović
authors.forename: N
authors.initials: N
authors.lastname: Bajić
authors.forename: R
authors.initials: R
authors.lastname: Kadić
authors.forename: V
authors.initials: V
authors.lastname: Popović-Brkić
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D018813:Multiple Endocrine Neoplasia Type 2a / Q000175:diagnosis*