Primary aldosteronism.
Primary aldosteronism is one of the few potentially curable forms of hypertension. This article highlights recent advances in the pathophysiology, diagnosis, and treatment of this relatively common secondary form of hypertension. These topics include the recognition that this disorder is more prevalent than previously assumed, the identification of high-risk populations that benefit most from screening, and the improved approaches to screening, diagnosis, localization, and treatment. This review uses illustrative examples to describe our approach to these patients.
Auchus
Richard J
RJ
Division of Endocrinology and Metabolism, UT Southwestern Medical Center, Dallas, TX 75390, USA. richard.auchus@UTSouthwestern.edu
Nwariaku
Fiemu E
FE
D000236:Adenoma; D006333:Heart Failure / Q000209:etiology*; D006801:Humans; D006929:Hyperaldosteronism / Q000175:diagnosis / Q000188:drug therapy / Q000503:physiopathology / Q000601:surgery; D008403:Mass Screening; D000451:Mineralocorticoid Receptor Antagonists / Q000627:therapeutic use; D012307:Risk Factors; D013148:Spironolactone / Q000627:therapeutic use
D000451:Mineralocorticoid Receptor Antagonists; D013148:Spironolactone