title: Supracricoid partial laryngectomies after radiation failure: a multi-institutional series.
abstract: BACKGROUND
  Radiation therapy (RT) is one of the gold standard treatments for early laryngeal cancer, and total laryngectomy is still the most applied surgical procedure after failure. Selected recurrences can be managed by supracricoid partial laryngectomies (SCPLs).
  
  
  METHODS
  A multi-institutional retrospective analysis was carried out in 78 consecutive patients treated by SCPLs for the recurrence of glottic-supraglottic cancer after RT. Cricohyoidoepiglottopexy was performed in 62, and cricohyoidopexy (CHP) in 16 cases.
  
  
  RESULTS
  Disease-free survival at 3 and 5 years were 95.5%. Early and late postoperative complications occurred in 27% and 17.9% of cases. Decannulation and satisfactory swallowing were achieved in 97.4% of cases.
  
  
  CONCLUSIONS
  SCPLs represent effective surgical organ-preservation strategies in the treatment of selected recurrences after RT failure, resulting in a good local control as well as functional recovery with acceptable morbidity, despite a complication rate which is not negligible.
authors.affiliation: Department of Otorhinolaryngology-Head and Neck Surgery, National Cancer Institute Regina Elena, Rome, Italy.
authors.forename: Raul
authors.initials: R
authors.lastname: Pellini
authors.forename: Barbara
authors.initials: B
authors.lastname: Pichi
authors.forename: Paolo
authors.initials: P
authors.lastname: Ruscito
authors.forename: Alberto Rinaldi
authors.initials: AR
authors.lastname: Ceroni
authors.forename: Umberto
authors.initials: U
authors.lastname: Caliceti
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Rizzotto
authors.forename: Antonio
authors.initials: A
authors.lastname: Pazzaia
authors.forename: Pasquale
authors.initials: P
authors.lastname: Laudadio
authors.forename: Cesare
authors.initials: C
authors.lastname: Piazza
authors.forename: Giorgio
authors.initials: G
authors.lastname: Peretti
authors.forename: Diana
authors.initials: D
authors.lastname: Giannarelli
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Spriano
mesh_terms: D000328:Adult; D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000401:mortality / Q000532:radiotherapy / Q000601:surgery*; D006801:Humans; D007822:Laryngeal Neoplasms / Q000401:mortality / Q000532:radiotherapy / Q000601:surgery*; D007825:Laryngectomy / Q000379:methods*; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D037981:Neck Dissection; D009364:Neoplasm Recurrence, Local / Q000601:surgery*; D011183:Postoperative Complications; D012189:Retrospective Studies; D013957:Thyroid Cartilage / Q000601:surgery; D017211:Treatment Failure; D014833:Voice Quality