More than satiety: central serotonin signaling and glucose homeostasis.
Serotonergic agents have been used in the past for reduction of appetite and body weight. As reported by Zhou et al. (2007) in this issue of Cell Metabolism, they also have unexpected effects on peripheral glucose homeostasis independent of food intake and body weight.
Pissios
Pavlos
P
Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.
Maratos-Flier
Eleftheria
E
D000818:Animals; D005947:Glucose / Q000378:metabolism*; D006706:Homeostasis / Q000187:drug effects*; D051379:Mice; D008954:Models, Biological; D058826:Serotonin 5-HT2 Receptor Agonists; D017366:Serotonin Receptor Agonists / Q000494:pharmacology*; D015398:Signal Transduction / Q000187:drug effects
D058826:Serotonin 5-HT2 Receptor Agonists; D017366:Serotonin Receptor Agonists; D005947:Glucose