title: Erythropoietic protoporphyria with eye complications.
abstract: We herein report a case of erythropoietic protoporphyria (EPP) complicated by a decrease in eyesight that occurred in a Japanese male. An ophthalmologist initially thought that the eyesight loss might be the result of idiopathic optic nerve atrophy due to a vascular obstruction in the fundus. There are no previous reports of EPP cases with eye complications. However, an eye abnormality has been reported in an animal model of protoporphyria after long-term, low-level exposure to blue light. As a result, in our case, it is therefore possible that a relationship may have existed between EPP and the onset of eye complications.
authors.affiliation: Department of Dermatology, Kitasato University School of Medicine, Kanagawa, Japan. derma-10@yokohamamc.hosp.go.jp
authors.forename: Hiromi
authors.initials: H
authors.lastname: Tsuboi
authors.forename: Kohzoh
authors.initials: K
authors.lastname: Yonemoto
authors.forename: Kensei
authors.initials: K
authors.lastname: Katsuoka
mesh_terms: D000328:Adult; D001284:Atrophy / Q000150:complications; D005654:Fundus Oculi; D006801:Humans; D008297:Male; D009900:Optic Nerve / Q000473:pathology*; D009901:Optic Nerve Diseases / Q000150:complications* / Q000473:pathology; D011166:Porphyrins / Q000097:blood; D046351:Protoporphyria, Erythropoietic / Q000097:blood / Q000150:complications* / Q000473:pathology; D012867:Skin / Q000473:pathology
chemical_list: D011166:Porphyrins