title: Diphenylprolinol silyl ether as catalyst of an asymmetric, catalytic, and direct Michael reaction of nitroalkanes with alpha,beta-unsaturated aldehydes.
abstract: A catalytic enantioselective direct conjugate addition of nitroalkanes to alpha,beta-unsaturated aldehydes using diphenylprolinol silyl ether as an organocatalyst has been developed. Using this methodology as a key step, short syntheses of therapeutically useful compounds have also been accomplished.
authors.affiliation: Department of Industrial Chemistry, Faculty of Engineering, Tokyo University of Science, Kagurazaka, Shinjuku-ku, Tokyo 162-8601, Japan.
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Gotoh
authors.forename: Hayato
authors.initials: H
authors.lastname: Ishikawa
authors.forename: Yujiro
authors.initials: Y
authors.lastname: Hayashi