Towards a method for printing a network of chick forebrain neurons for biosensor applications.
The primary goal of this work is to establish a robust, repeatable method for printing arrays of neurons. This work has two endpoints. One is to use a neural array as an experimental testbed for investigating neuronal cell growth hypotheses. The other endpoint is to enable the next generation of cell-based sensors. Herein we compare microcontact printing results previously published by our group with a new method of dip-pen printing. We present preliminary results for neurons growing on these microprinted arrays, assessing contact frequencies and growth characteristics.
Sasoglu
F Mert
FM
Drexel University, Department of Mechanical Engineering and Mechanics, Philadelphia, PA 19104, USA.
Kilinc
Devrim
D
Allen
Kathleen
K
Layton
Bradley
B
D000818:Animals; D018929:Cell Culture Techniques / Q000295:instrumentation* / Q000379:methods*; D002642:Chick Embryo; D009434:Neural Pathways / Q000166:cytology* / Q000254:growth & development; D009474:Neurons / Q000166:cytology*; D016548:Prosencephalon / Q000166:cytology* / Q000196:embryology