Metabolic syndrome is a predictor for an ECG sign of no-reflow after primary PCI in patients with acute ST-elevation myocardial infarction.
OBJECTIVE
The purpose of this study was to evaluate both the predictive value of metabolic syndrome (MS) on no-reflow phenomenon and 30-day clinical outcomes on patients undergoing primary percutaneous coronary intervention (PCI) for acute ST-elevation myocardial infarction (STEMI).


RESULTS
One hundred and twelve consecutive patients (mean age 57+/-11 years, 94 male) with acute STEMI treated with primary PCI were analysed prospectively. Sum of ST-segment elevation was obtained immediately before and 60 min after the restoration of TIMI-3 flow. The difference between two measurements was accepted as the amount of ST-segment resolution and was expressed as summation operatorSTR. summation operatorSTR<50% was accepted as ECG sign of no-reflow phenomenon. Metabolic syndrome was defined based on Adult Treatment Panel-III criteria. The no-reflow was found in 22.3% of the entire group and was significantly higher in patients with MS than those without MS (43.7% vs. 13.7%, p<0.001). There was no significant difference in no-reflow between patients who had both MS and diabetes mellitus (DM) and patients who had MS but not DM (42.5% vs. 50%, respectively; p>0.05).


CONCLUSIONS
The presence of MS may play an important role in the occurrence of no- reflow in STEMI treated with primary PCI.
Tartan
Zeynep
Z
Department of Cardiology, Siyami Ersek Cardiovascular and Thoracic Surgery Centre, Tibbiye Caddesi, Hayadarpasa, Istanbul, Turkey. drztartan@yahoo.com
Ozer
Nihat
N
Uyarel
Huseyin
H
Akgul
Ozgur
O
Gul
Mehmet
M
Cetin
Mustafa
M
Kasikcioglu
Hulya
H
Cam
Nese
N
D015906:Angioplasty, Balloon, Coronary; D003326:Coronary Circulation; D004562:Electrocardiography / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D024821:Metabolic Syndrome / Q000150:complications* / Q000503:physiopathology; D008875:Middle Aged; D009203:Myocardial Infarction / Q000503:physiopathology* / Q000628:therapy*; D054318:No-Reflow Phenomenon / Q000453:epidemiology / Q000209:etiology*; D011237:Predictive Value of Tests; D011446:Prospective Studies; D012307:Risk Factors; D013997:Time Factors; D016896:Treatment Outcome