Mechanical properties of subchondral bone in degenerative joint disease.
Analysis of the role which subchondral bone plays in etiopathogenesis of the arthrotic joint diseases continues for a long time. Introduction of the new imaging techniques helps to evaluate those changes clearly. The work is a presentation of the current views on correlation between changes in bone and overlaying articular surfaces in consideration with potential possibilities of therapeutic intervention. It also contains a discussion on the Ball'a theory from 1966, who thought that osteoarthrosis protects against osteoporosis. Actually, it's well known, that both processes coexists and could be correlated. Kaneko's theories presented in this paper, helps to evaluate the role of inflammatory cytokines and proteinases in subchondral destruction and arthrosis. Probably in this field we can find the possible way to modify this process in modern therapies.
Chmielewski
Dariusz
D