Hypernatraemia and rhabdomyolysis.
A 44-year-old man with a history of childhood brain injury presented with dysarthria, confusion, reduced oral intake and reduced mobility after a week of heatwave conditions. He had severe hypernatraemia and raised serum creatine kinase levels, consistent with rhabdomyolysis. In most previous case reports linking hypernatraemia and rhabdomyolysis, other factors have potentially contributed. From the available evidence, severe hypernatraemia alone appears sufficient to induce muscle injury.
Denman
Jason P
JP
Department of Internal Medicine, Royal Brisbane and Women's Hospital, Brisbane, Queensland, Australia. Jason_Denman@health.qld.gov.au
D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001930:Brain Injuries; D003402:Creatine Kinase / Q000097:blood; D003681:Dehydration / Q000209:etiology; D006233:Persons with Disabilities; D005440:Fluid Therapy; D018882:Heat Stress Disorders / Q000150:complications / Q000628:therapy; D006801:Humans; D006955:Hypernatremia / Q000150:complications* / Q000209:etiology / Q000628:therapy; D008297:Male; D017582:Renal Replacement Therapy; D012206:Rhabdomyolysis / Q000150:complications* / Q000209:etiology / Q000628:therapy
D000900:Anti-Bacterial Agents; D003402:Creatine Kinase