Determination of the lesion size in Laser-induced Interstitial Thermal Therapy (LITT) using a low-field MRI.
This study aimed to compare MR thermal mapping during Laser-induced Interstitial Thermal Therapy (LITT) to thermal lesions observed macroscopically, in order to estimate the 3D size of the coagulative necrosis. Laser irradiation was performed ex-vivo with a 980 nm laser in pig liver in a open low-magnetic field (0.2T) scanner. The laser light was transmitted through a 1040/600 microm (outer/core diameter) bare-tip silica fiber. The laser energy was applied on a pulsed mode (10 s laser-on, 10 s laser-off) for 12 minutes, power: 6W, energy: 2160 J. MR thermal mapping used T1 method for its simplicity and its efficiency at low magnetic field.
Viard
Romain
R
Inserm, U703, Lille, France. r-viard@chrulille.fr
Emptaz
Aline
A
Piron
Bérengère
B
Rochon
Philippe
P
Wassmer
Benjamin
B
Mordon
Serge
S
D006801:Humans; D006979:Hyperthermia, Induced / Q000295:instrumentation / Q000379:methods*; D053685:Laser Therapy / Q000379:methods; D008113:Liver Neoplasms / Q000473:pathology / Q000556:secondary* / Q000628:therapy*; D008279:Magnetic Resonance Imaging / Q000295:instrumentation / Q000379:methods*; D008954:Models, Biological; D011237:Predictive Value of Tests