title: Neuromuscular adaptation to early post-operative, high-intensity, short resistance training of non-operated lower extremity in elderly patients: a randomized controlled trial.
abstract: OBJECTIVE
  To evaluate the short-term effects of high-intensity, task-specific vs regular rehabilitation programme on neuromuscular activity and functional changes in elderly inpatients.
  
  
  METHODS
  Single-blind, randomized controlled trial.
  
  
  METHODS
  Sixty-two patients, aged 74.1 (standard deviation (SD) 6.9) years, 12.8 (SD 3.6) days after operation of one lower limb.
  
  
  METHODS
  Allocation to either high- or regular-intensity strength training of non-operated limb, of 3 weeks duration.
  
  
  METHODS
  ratio of integrated electromyography per weight lifted (mm vastus medialis and lateralis), isometric electromyography (EMG), maximal weight lifted expressed as 1 repetition maximum, torque in Nm and isometric maximal force of uninvolved leg, timed "up and go" test (TUG) and Western Ontario and McMaster Universities (WOMAC) questionnaire.
  
  
  RESULTS
  Both programmes resulted in significant improvements in: integrated EMG/weight lifted ratio, isometric EMG, 1 repetition maximum, torque and isometric force, TUG performance and WOMAC items (all p < 0.0001, Wilcoxon signed-rank test). Significant differences were found between the high- and regular-intensity groups for integrated EMG/weight lifted (p = 0.026), 1 repetition maximum and torque (p = 0.0014, Wilcoxon rank-sum test).
  
  
  CONCLUSIONS
  High-intensity, short-period, early postoperative muscle training has a superior effect on maximal weight lifted by the knee extensors and integrated EMG/weight lifted compared with regular raining. These findings are in accordance with more rapid neuronal adaptation by a high intensity rehabilitation programme.
authors.affiliation: 1Department of Rheumatology and Clinical Immunology/Allergology, University Hospital, Berne, Switzerland. a.tal@rehabern.ch
authors.forename: Amir
authors.initials: A
authors.lastname: Tal-Akabi
authors.forename: Ursula
authors.initials: U
authors.lastname: Steiger
authors.forename: Peter M
authors.initials: PM
authors.lastname: Villiger
mesh_terms: D000368:Aged; D019645:Arthroplasty, Replacement, Knee / Q000534:rehabilitation*; D015331:Cohort Studies; D004576:Electromyography; D005528:Foot / Q000503:physiopathology / Q000601:surgery; D005593:Fracture Fixation, Internal / Q000534:rehabilitation*; D006801:Humans; D007537:Isometric Contraction; D007717:Knee / Q000503:physiopathology / Q000601:surgery; D007866:Leg / Q000503:physiopathology*; D009043:Motor Activity; D053580:Muscle Strength; D018482:Muscle, Skeletal / Q000502:physiology; D017063:Outcome Assessment, Health Care; D011184:Postoperative Period; D011446:Prospective Studies; D011795:Surveys and Questionnaires