Genomic approaches in genetic research for endocrine diseases.
Genomic research has made great progress to understanding functional roles in noncoding DNA sequences. In particular, approaches to identify regulatory elements with enhancer/silencer function based on the synergism between computational and experimental techniques are discussed. Such approaches have been applied to gene-directed as well as genome-wide investigations.
Ravazzolo
Roberto
R
Laboratory of Molecular Genetics, G. Gaslini Institute, and Department of Pediatrics and CEBR, University of Genova, Genova, Italy.
D000818:Animals; D002843:Chromatin / Q000378:metabolism / Q000502:physiology; D003094:Collagen / Q000235:genetics; D024042:Collagen Type I; D004700:Endocrine System Diseases / Q000235:genetics*; D023281:Genomics / Q000379:methods*; D006801:Humans; D008954:Models, Biological
D002843:Chromatin; D024042:Collagen Type I; D003094:Collagen