title: A second-generation combined linkage physical map of the human genome.
abstract: We have completed a second-generation linkage map that incorporates sequence-based positional information. This new map, the Rutgers Map v.2, includes 28,121 polymorphic markers with physical positions corroborated by recombination-based data. Sex-averaged and sex-specific linkage map distances, along with confidence intervals, have been estimated for all map intervals. In addition, a regression-based smoothed map is provided that facilitates interpolation of positions of unmapped markers on this map. With nearly twice as many markers as our first-generation map, the Rutgers Map continues to be a unique and comprehensive resource for obtaining genetic map information for large sets of polymorphic markers.
authors.affiliation: Department of Genetics, Rutgers University, Piscataway, New Jersey 08854, USA. matise@biology.rutgers.edu
authors.forename: Tara C
authors.initials: TC
authors.lastname: Matise
authors.forename: Fang
authors.initials: F
authors.lastname: Chen
authors.forename: Wenwei
authors.initials: W
authors.lastname: Chen
authors.forename: Francisco M
authors.initials: FM
authors.lastname: De La Vega
authors.forename: Mark
authors.initials: M
authors.lastname: Hansen
authors.forename: Chunsheng
authors.initials: C
authors.lastname: He
authors.forename: Fiona C L
authors.initials: FC
authors.lastname: Hyland
authors.forename: Giulia C
authors.initials: GC
authors.lastname: Kennedy
authors.forename: Xiangyang
authors.initials: X
authors.lastname: Kong
authors.forename: Sarah S
authors.initials: SS
authors.lastname: Murray
authors.forename: Janet S
authors.initials: JS
authors.lastname: Ziegle
authors.forename: William C L
authors.initials: WC
authors.lastname: Stewart
authors.forename: Steven
authors.initials: S
authors.lastname: Buyske
mesh_terms: D016001:Confidence Intervals; D005260:Female; D008040:Genetic Linkage; D005819:Genetic Markers; D015894:Genome, Human; D005838:Genotype; D006801:Humans; D008297:Male; D020161:Physical Chromosome Mapping / Q000379:methods / Q000706:statistics & numerical data; D020641:Polymorphism, Single Nucleotide
chemical_list: D005819:Genetic Markers