title: Femoral and lower costosternal junctions' osteitis in an adult with SAPHO syndrome: An unusual presentation.
abstract: The combination of synovitis, acne, pustulosis, hyperostosis and aseptic osteitis is known as SAPHO syndrome. Osteitis involves the anterior chest, particularly the sternoclavicular and upper costosternal junctions. Diagnosis is difficult when there are no typical skin and bone lesions and differential diagnosis includes bacterial ostomyelitis, malignancy and Paget's disease. We present a case of SAPHO syndrome with aseptic femoral osteitis and symmetrical involvement of the lower costosternal junctions. The main advantage of recognition and diagnosis of SAPHO syndrome is the avoidance of unnecessary prolonged antibiotic treatment and repeated invasive procedures.
authors.affiliation: 5th Department of Internal Medicine, Evangelismos Hospital, 45-47 Hipsilantou Street, Kolonaki, GR-106 76 Athens, Greece. emylon@med.uoa.gr
authors.forename: Eleni
authors.initials: E
authors.lastname: Mylona
authors.forename: Styliani
authors.initials: S
authors.lastname: Golfinopoulou
authors.forename: Christos
authors.initials: C
authors.lastname: Peppas
authors.forename: Panagiotis
authors.initials: P
authors.lastname: Fanourgiakis
authors.forename: Athanasios
authors.initials: A
authors.lastname: Skoutelis
mesh_terms: D020083:Acquired Hyperostosis Syndrome / Q000150:complications / Q000175:diagnosis*; D005260:Female; D005269:Femur; D006801:Humans; D008875:Middle Aged; D010000:Osteitis / Q000209:etiology; D013248:Sternocostal Joints