Chromium hexacyanoferrate modified biosensor based on PQQ-dependent glucose dehydrogenase.
A Pyrroloquinoline quinone (PQQ)-dependent glucose dehydrogenase based platinum electrode was developed to detect glucose. Chromium hexacyanoferrate was modified onto this electrode to serve as an electron transfer mediator between PQQ and the platinum electrode. This biosensor showed the optimal response of glucose measurements at pH 7 and an operation potential of +0.4 V (vs. Ag/AgCl). More importantly the lifespan of the biosensor has been last for 47 days without significant enzyme activity degradation.
Tseng
Ta-Feng
TF
Biomedical Engineering Department, Chung-Yuan Christian University, Chung-Li 32023, Taiwan, ROC. g9402502@cycu.edu.tw
Yang
Yang-Li
YL
Lou
Shyh-Liang
SL
D015374:Biosensing Techniques; D002857:Chromium / Q000737:chemistry*; D004579:Electron Transport; D005295:Ferrocyanides / Q000737:chemistry*; D005947:Glucose / Q000032:analysis*; D005948:Glucose Dehydrogenases / Q000737:chemistry*; D045542:PQQ Cofactor / Q000737:chemistry*
D005295:Ferrocyanides; C116383:ferrocyn; D002857:Chromium; D045542:PQQ Cofactor; D005948:Glucose Dehydrogenases; D005947:Glucose