Cobalt-catalyzed intermolecular C-H amination with bromamine-T as nitrene source.
Cobalt, supported by porphyrin ligands, is capable of catalyzing intermolecular nitrene insertion of sp(3) C-H bonds with bromamine-T as the nitrene source, forming the desired tosyl-protected amines with NaBr as the by-product.
Harden
Jeremiah D
JD
Department of Chemistry, University of South Florida, Tampa, FL 33620-5250, USA.
Ruppel
Joshua V
JV
Gao
Guang-Yao
GY
Zhang
X Peter
XP
D000586:Amination; D000588:Amines / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D003035:Cobalt / Q000737:chemistry*; D020650:Combinatorial Chemistry Techniques; D007097:Imines / Q000737:chemistry*; D008024:Ligands; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D011166:Porphyrins / Q000737:chemistry*; D013237:Stereoisomerism; D013449:Sulfonamides / Q000737:chemistry*
D000588:Amines; D007097:Imines; D008024:Ligands; D009942:Organometallic Compounds; D011166:Porphyrins; D013449:Sulfonamides; C017621:phenylnitrene; D003035:Cobalt; C048239:bromamine T