title: Successful liver retransplantation for recurrent hepatopulmonary syndrome.
abstract: HPS is defined as arterial hypoxemia because of pulmonary vasodilation as a result of cirrhotic or non-cirrhotic portal hypertension. This report describes a teenager with HPS because of primary sclerosing cholangitis/autoimmune hepatitis overlap syndrome requiring OLT. HPS resolved completely within three months of OLT, but recurred again at 12 months post-OLT following liver dysfunction secondary to a biliary stricture. She underwent a second OLT successfully and remains well two yr and three months post-second OLT. Recurrent HPS after OLT may occur because of graft dysfunction and as this novel case illustrates, retransplantation may lead to a successful outcome.
authors.affiliation: Children's Liver and GI Unit, St. James's University Hospital, Leeds, UK. sanjay.rajwal@leedsth.nhs.uk
authors.forename: S R
authors.initials: SR
authors.lastname: Rajwal
authors.forename: S M
authors.initials: SM
authors.lastname: Davison
authors.forename: R
authors.initials: R
authors.lastname: Prasad
authors.forename: K
authors.initials: K
authors.lastname: Brownlee
authors.forename: P
authors.initials: P
authors.lastname: McClean
mesh_terms: D000293:Adolescent; D000792:Angiography; D002760:Cholangiopancreatography, Endoscopic Retrograde; D005260:Female; D005500:Follow-Up Studies; D020065:Hepatopulmonary Syndrome / Q000175:diagnosis / Q000601:surgery*; D006801:Humans; D016031:Liver Transplantation / Q000379:methods*; D012008:Recurrence; D012086:Reoperation; D012720:Severity of Illness Index; D014057:Tomography, X-Ray Computed