[Cutaneous inflammatory pseudotumor (plasmocytoid granuloma)].
Cutaneous inflammatory pseudotumor is a rare benign condition that should be macroscopically differentiated, from dermatofibroma and metastases of carcinoma and, histologically from cutaneous lymphomas and other more aggressive diseases. We report herein the case of a 63-year-old man with a painless nodule of the left arm skin with a rapid growth (1 month ago). The histological examination revealed a well-defined dermal nodule of plasmacytoid cells, without connection or infiltration of the epidermis. At high power the polymorphous cellular infiltrate was, constituted by medium- small elements with widespread features of lympho-plasmocytoid differentiation or clear plasmacellular features. Immunohistochemical analysis showed a polyclonal cytological pattern with expression of both immunoglobulin light chains kappa e lambda by plasmacytoid and admixed B and T lymphocytes. The final diagnosis was Plasmocytoid granuloma an entity that is recognized within the so called "Cutaneous inflammatory pseudotumor" together with the myofibroblastic tumor.
Pagni
F
F
Dipartimento di Scienze Chirurgiche Università di Milano "Bicocca", U.O. Anatomia Patologica, Ospedale Civile di Vimercate, Presidio di Desio, Italy. petala.83@tiscali.it
D001132:Arm; D001402:B-Lymphocytes; D006104:Granuloma, Plasma Cell / Q000473:pathology* / Q000601:surgery; D006801:Humans; D007249:Inflammation; D008297:Male; D008875:Middle Aged; D012871:Skin Diseases / Q000473:pathology* / Q000601:surgery; D013601:T-Lymphocytes