Mitigating selection in HLA-B27 not confirmed.
The existence of a small, discrete group of HLA-B27 promoters, potentially able to mitigate the deleterious effect of this allele, has not been confirmed.
Müller
B
B
Institute of Immunology, Rostock University, Rostock, Germany.
Pavesio
C
C
Eggert
M
M
Neek
G
G
Mitchison
N
N
D015796:HLA-B27 Antigen / Q000235:genetics*; D006801:Humans; D015850:Interleukin-6 / Q000235:genetics; D011401:Promoter Regions, Genetic; D012641:Selection, Genetic
D015796:HLA-B27 Antigen; D015850:Interleukin-6