title: Progress and prospects: gene therapy clinical trials (part 2).
abstract: This is the second part of a review summarizing progress and prospects in gene therapy clinical research. Twenty key diseases/strategies are succinctly described and commented on by leaders in the field. This part includes clinical trials for skin diseases, neurological disorders, HIV/AIDS, ornithine transcarbamylase deficiency, alpha(1)-antitrypsin deficiency, haemophilia and cancer.
authors.affiliation: Department of Gene Therapy, Emmanuel kaye Building, NHLI, Imperial College, Manresa Road, London, UK.
authors.forename: Eric
authors.initials: E
authors.lastname: Alton
authors.forename: Stefano
authors.initials: S
authors.lastname: Ferrari
authors.forename: Uta
authors.initials: U
authors.lastname: Griesenbach
authors.forename: A
authors.initials: A
authors.lastname: Aiuti
authors.forename: A C
authors.initials: AC
authors.lastname: Bachoud-Lévi
authors.forename: A
authors.initials: A
authors.lastname: Blesch
authors.forename: M K
authors.initials: MK
authors.lastname: Brenner
authors.forename: F
authors.initials: F
authors.lastname: Cattaneo
authors.forename: E A
authors.initials: EA
authors.lastname: Chiocca
authors.forename: G
authors.initials: G
authors.lastname: Gao
authors.forename: K A
authors.initials: KA
authors.lastname: High
authors.forename: A M
authors.initials: AM
authors.lastname: Leen
authors.forename: N R
authors.initials: NR
authors.lastname: Lemoine
authors.forename: I A
authors.initials: IA
authors.lastname: McNeish
authors.forename: G
authors.initials: G
authors.lastname: Meneguzzi
authors.forename: M
authors.initials: M
authors.lastname: Peschanski
authors.forename: M G
authors.initials: MG
authors.lastname: Roncarolo
authors.forename: D S
authors.initials: DS
authors.lastname: Strayer
authors.forename: M H
authors.initials: MH
authors.lastname: Tuszynski
authors.forename: D J
authors.initials: DJ
authors.lastname: Waxman
authors.forename: J M
authors.initials: JM
authors.lastname: Wilson
mesh_terms: D002986:Clinical Trials as Topic; D018014:Gene Transfer Techniques / Q000009:adverse effects / Q000639:trends; D015316:Genetic Therapy / Q000379:methods / Q000639:trends*; D005822:Genetic Vectors; D006801:Humans; D009369:Neoplasms / Q000628:therapy; D033581:Stem Cell Transplantation / Q000009:adverse effects / Q000639:trends