title: [Polymyositis and interstitial lung disease with a favorable response to corticosteroids and methotrexate].
abstract: Polymyositis is a rare collagen disease that can involve the lungs. Between 5% and 30% of patients with polymyositis present interstitial lung disease at diagnosis or during the course of disease. Onset is usually insidious and involves dyspnea and nonproductive cough. Several histopathological findings are associated with polymyositis and the most common is nonspecific interstitial pneumonia. The prognosis of interstitial lung disease associated with polymyositis is better than that of idiopathic pulmonary fibrosis, since most patients respond to treatment with corticosteroids and immunosuppressants. We report the case of a 60-year-old woman with dyspnea and muscle weakness who was diagnosed with polymyositis and interstitial lung disease (radiography indicated possible nonspecific interstitial pneumonia). The patient responded well to prednisone and methotrexate.
authors.affiliation: Servicio de Neumología, Hospital de La Princesa, Madrid, España.
authors.forename: Nieves
authors.initials: N
authors.lastname: Hoyos
authors.forename: Alvaro
authors.initials: A
authors.lastname: Casanova
authors.forename: Silvia
authors.initials: S
authors.lastname: Sánchez
authors.forename: Claudia
authors.initials: C
authors.lastname: Valenzuela
authors.forename: Asunción
authors.initials: A
authors.lastname: García
authors.forename: Rosa María
authors.initials: RM
authors.lastname: Girón
mesh_terms: D000893:Anti-Inflammatory Agents / Q000627:therapeutic use*; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D017563:Lung Diseases, Interstitial / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000473:pathology; D008727:Methotrexate / Q000627:therapeutic use*; D008875:Middle Aged; D017285:Polymyositis / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000473:pathology; D011241:Prednisone / Q000627:therapeutic use*; D014057:Tomography, X-Ray Computed
chemical_list: D000893:Anti-Inflammatory Agents; D000970:Antineoplastic Agents; D011241:Prednisone; D008727:Methotrexate