A simple and efficient procedure of low valent iron- or copper-mediated Reformatsky reaction of aldehydes.
An operationally simple and very efficient procedure of Reformatsky reaction of aldehydes has been carried out in THF in the presence of low valent iron or copper which were prepared in situ employing a bimetal redox strategy through reduction of FeCl3 or CuCl2-2H2O with magnesium.
Chattopadhyay
Angshuman
A
Bio-Organic Division, Bhabha Atomic Research Centre, Mumbai, India. achat@apsara.barc.ernet.in
Dubey
Akhil Kr
AK
D000447:Aldehydes / Q000737:chemistry*; D002712:Chlorides; D003300:Copper / Q000737:chemistry*; D005290:Ferric Compounds / Q000737:chemistry; D005663:Furans / Q000737:chemistry; D007501:Iron / Q000737:chemistry*; D008274:Magnesium / Q000737:chemistry; D008956:Models, Chemical; D010084:Oxidation-Reduction
D000447:Aldehydes; D002712:Chlorides; D005290:Ferric Compounds; D005663:Furans; C018674:tetrahydrofuran; D003300:Copper; D007501:Iron; D008274:Magnesium; C029892:cupric chloride; C024555:ferric chloride