Vitamin D status is not associated with the risk of hospitalization for acute bronchiolitis in early childhood.
The association between vitamin D status and susceptibility to acute lower respiratory tract infection (ALRI) was studied in young Canadian children. Serum 25-hydroxyvitamin D (25(OH)D) concentrations were measured in patients aged 1-25 months admitted to hospital with uncomplicated ALRI (primarily viral bronchiolitis) as well as in healthy, similarly aged patients without a history of hospitalization for ALRI (controls). Serum 25(OH)D concentrations were similar among cases and controls (77.0 versus 77.2 nmol l(-1); P=0.960), and there was no case-control difference in the prevalence of vitamin D insufficiency using two thresholds (<40 nmol l(-1): 4.7 versus 1.5%, P=0.365; <80 nmol l(-1): 51.6 versus 56.9%, P=0.598). Vitamin D status was not associated with the risk of hospitalization for ALRI in this population.
Roth
D E
DE
Department of Pediatrics, Faculty of Medicine, University of Alberta, Edmonton, Alberta, Canada. droth@jhsph.edu
Jones
A B
AB
Prosser
C
C
Robinson
J L
JL
Vohra
S
S
D001988:Bronchiolitis / Q000453:epidemiology / Q000209:etiology*; D005260:Female; D006760:Hospitalization; D006801:Humans; D007223:Infant; D008297:Male; D011014:Pneumonia / Q000453:epidemiology / Q000209:etiology*; D012307:Risk Factors; D014807:Vitamin D / Q000031:analogs & derivatives* / Q000097:blood; D014808:Vitamin D Deficiency / Q000150:complications*
D014807:Vitamin D; C104450:25-hydroxyvitamin D