The electrophysiological and functional effect of shock wave on peripheral nerves.
Recently, extracorporeal shock wave therapy (ESWT) is found to be effective for musculoskeletal disorders, such as calcific tendonitis, epicondylitis, and plantar fasciitis. Until now, there is no study on the influence of ESWT on motor nerve and the underlying mechanism of ESWT on musculoskeletal disorders remains unclear. This study evaluated the effects of shock wave of different intensity on peripheral nerves and the tracking of long term observation on induced injury. Shock wave treatments of different intensity were applied on the sciatic nerve of rat and electrophysiological changes were recorded. Besides, the functional activities were estimated with sciatic functional index (SFI). The results showed a decrease of motor nerve conduction velocity (MNCV) after shock wave treatment, but recovery was observed within 14 days. When the intensity of shock wave was higher, the decrease of MNCV sustained longer. There was no significant change in functional assessment. It is suggested that ESWT may be harmless to peripheral nerves and can be used in the treatment of musculoskeletal disorders.
Wu
Yi-Hui
YH
Department of Electrical Engineering, National Taiwan University.
Lun
Jer-Junn
JJ
Chen
Wen-Shiang
WS
Chong
Fok-Ching
FC
D000818:Animals; D001703:Biophysics / Q000379:methods; D004594:Electrophysiology / Q000295:instrumentation* / Q000379:methods*; D004867:Equipment Design; D008297:Male; D015233:Models, Statistical; D009046:Motor Neurons / Q000378:metabolism; D009140:Musculoskeletal Diseases / Q000473:pathology*; D009416:Nerve Regeneration; D009474:Neurons / Q000378:metabolism; D010525:Peripheral Nerves / Q000473:pathology*; D017933:Peripheral Nervous System / Q000473:pathology*; D051381:Rats; D017208:Rats, Wistar; D013997:Time Factors