[Effect of semiconductor quantum dots on cyto-biological behavior of tongue squamous cell carcinoma cell line Tca8113].
OBJECTIVE
To study the effect of semiconductor quantum dots (QD), a kind of new luminescent inorganic non-crystals on biological behavior of tongue squamous cell carcinoma cell line Tca8113.


METHODS
Different concentrations of QD were cocultured with Tca8113 cells, and the status of cancer cell growth in three experimental groups and control was compared respectively. Tca8113 cells were labeled by QD (Tca8113-QD), and then transwell chambers and washing away method were used to detect the difference of invasion and metastatic ability between Tca8113-QD and Tca8113 cells.


RESULTS
The different concentrations of QD showed no negative effects on growth of Tca8113 cells. The ability of invasion, attachment and chemotaxis movement of Tca8113 cells were not significantly different between the experimental groups and control.


CONCLUSIONS
QD showed no effects on growth, invasion and metastatic ability of Tca8113 cells and may serve as a new fluorescence probe in living tumor cell study.
Yang
Kai
K
Department of Oral and Maxillofacial Surgery, The First Affiliated Hospital, Chongqing Medical University, Chongqing 400016, China. cqfyyk@yahoo.com.cn
Sun
De-ping
DP
Chen
Rui
R
D002294:Carcinoma, Squamous Cell / Q000473:pathology*; D002448:Cell Adhesion; D045744:Cell Line, Tumor; D002465:Cell Movement; D006801:Humans; D009361:Neoplasm Invasiveness; D045663:Quantum Dots; D014062:Tongue Neoplasms / Q000473:pathology*