title: Pigmented lesions clinic for early detection of melanoma: preliminary results.
abstract: BACKGROUND
  Early detection of malignant melanoma of the skin is the most important factor in patient survival. Naked-eye diagnostic sensitivity and specificity are low. Patients with multiple nevi are at high risk to develop melanomas and the clinical follow-up of such patients is difficult, resulting in missed melanomas on the one hand and unnecessary biopsies on the other.
  
  
  OBJECTIVE
  To describe the set-up of a special clinic aimed at early detection of melanoma and follow-up of high risk patients and preliminary results from 20 months of operation.
  
  
  METHODS
  We established a pigmented lesions clinic based on a digital photography studio enabling documentation and comparison over time of full body photography and dermoscopy.
  
  
  RESULTS
  In the first 20 months of work, 895 patients were seen, 206 of them for follow-up visits. A total of 29,254 photos were taken. Altogether, 236 lesions were suspicious (either clinically or dermoscopically) and the patients were advised to excise them. Seven melanomas were found in this initial examination (which did not include long-term follow-up).
  
  
  CONCLUSIONS
  With multimode photographic cutaneous surveillance, early detection of melanoma in high risk patients has been reported. Our clinic utilizes the same techniques and diagnostic algorithm as other leading clinics throughout the world, thus enabling us to deliver better follow-up for those patients.
authors.affiliation: Department of Dermatology, Sheba Medical Center, Tel Hashomer, Israel. pigment@sheba.health.gov.il
authors.forename: Nir
authors.initials: N
authors.lastname: Nathansohn
authors.forename: Arie
authors.initials: A
authors.lastname: Orenstein
authors.forename: Henri
authors.initials: H
authors.lastname: Trau
authors.forename: Alon
authors.initials: A
authors.lastname: Liran
authors.forename: Jacob
authors.initials: J
authors.lastname: Schachter
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D000554:Ambulatory Care Facilities; D002648:Child; D002675:Child, Preschool; D046169:Dermoscopy / Q000295:instrumentation*; D042241:Early Diagnosis; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008403:Mass Screening / Q000295:instrumentation / Q000379:methods*; D008545:Melanoma / Q000175:diagnosis* / Q000517:prevention & control; D008875:Middle Aged; D009508:Nevus, Pigmented / Q000175:diagnosis*; D010781:Photography / Q000295:instrumentation*; D010858:Pigmentation; D011159:Population Surveillance / Q000379:methods; D011446:Prospective Studies; D012307:Risk Factors; D012680:Sensitivity and Specificity; D012878:Skin Neoplasms / Q000175:diagnosis* / Q000517:prevention & control; D013997:Time Factors