title: Hereditary haemorrhagic telangiectasia treated by pulsed neodymium:yttrium-aluminium-garnet (Nd:YAG) laser (1,064 nm).
abstract: Hereditary haemorrhagic telangiectasia (HHT) is a familial, autosomal, dominant, multi-system, vascular, dysplasia. Besides repetitive epistaxis, cutaneous eruptive macules and nodules lead to recurring bleeding and cosmetic problems. We report on a pilot study of four cases of HHT in which cutaneous lesions were treated with a pulsed neodymium:yttrium-aluminum-garnet (Nd:YAG) laser (1,064 nm). Pulsed Nd:YAG laser treatment, without anaesthesia, was performed several times on eruptive angiomas on palmar and facial skin. Lesions on fingers and face mostly showed very good, or even complete, clearing after the first laser treatment. Several macules required multiple treatment; only a few lesions showed no effect. Pulsed Nd:YAG laser therapy (1,064 nm) appears to be an effective and safe treatment option for hereditary haemorrhagic telangiectasia on the skin of face and extremities.
authors.affiliation: Department of Dermatology, University Hospital of Regensburg, Franz-Josef-Strauss-Allee 11, 93042 Regensburg, Germany. annegret.werner@klinik.uni-regensburg.de
authors.forename: A
authors.initials: A
authors.lastname: Werner
authors.forename: W
authors.initials: W
authors.lastname: Bäumler
authors.forename: S
authors.initials: S
authors.lastname: Zietz
authors.forename: T
authors.initials: T
authors.lastname: Kühnel
authors.forename: U
authors.initials: U
authors.lastname: Hohenleutner
authors.forename: M
authors.initials: M
authors.lastname: Landthaler
mesh_terms: D000368:Aged; D005145:Face / Q000528:radiation effects; D005260:Female; D006391:Hemangioma / Q000601:surgery; D006801:Humans; D007834:Lasers; D053844:Lasers, Solid-State; D008297:Male; D008875:Middle Aged; D010865:Pilot Projects; D012867:Skin / Q000528:radiation effects; D013683:Telangiectasia, Hereditary Hemorrhagic / Q000503:physiopathology / Q000601:surgery*; D016896:Treatment Outcome