Three new C21-steroidal glycosides from the roots of Cynanchum inamoenum.
Three new C(21)-steroidal glycosides presenting an unusual 13,14:14,15-disecopregnane-type skeleton, named inamosides A-C (1-3), together with two known C(21)-steroidal glycosides, were isolated from the MeOH extract of the roots of Cynanchum inamoeum (Maxim.) Loes (Asclepiadaceae). The aglycone of compounds 1, 2, and 3 has a 2beta-hydroxyl, which has not yet been reported in the literature. The structure and relative configuration of the aglycone of compounds 1, 2, and 3 were established by X-ray crystallographic analysis.
Wang
Li-Qin
LQ
State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Kunming, China.
Lu
Yang
Y
Zhao
You-Xing
YX
Zhou
Jun
J
Zheng
Qi-Tai
QT
D029062:Apocynaceae / Q000737:chemistry*; D018360:Crystallography, X-Ray; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D018517:Plant Roots / Q000737:chemistry*; D013256:Steroids / Q000737:chemistry / Q000302:isolation & purification*
D006027:Glycosides; D013256:Steroids