title: FeCl3-catalyzed nucleophilic substitution of propargylic acetates with enoxysilanes.
abstract: An efficient FeCl3-catalyzed substitution reaction of propargylic acetates with enoxysilanes under mild conditions to afford corresponding gamma-alkynyl ketones has been developed. The substitution reaction is followed by a TsOH-catalyzed cyclization without purification of the gamma-alkynyl ketone intermediates, offering a straightforward synthetic route to tri- or tetrasubstituted furans.
authors.affiliation: Department of Chemistry, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361005, Fujian, People's Republic of China. zpzhan@xmu.edu.cn
authors.forename: Zhuang-ping
authors.initials: ZP
authors.lastname: Zhan
authors.forename: Xu-bin
authors.initials: XB
authors.lastname: Cai
authors.forename: Shao-pei
authors.initials: SP
authors.lastname: Wang
authors.forename: Jing-liang
authors.initials: JL
authors.lastname: Yu
authors.forename: Hui-juan
authors.initials: HJ
authors.lastname: Liu
authors.forename: Yuan-yuan
authors.initials: YY
authors.lastname: Cui