Dandy-Walker syndrome and chromosomal abnormalities.
Dandy-Walker syndrome (DWS) is a brain malformation of unknown etiology, but several reports have been published indicating that there is a causal relationship to various types of chromosomal abnormalities and malformation syndromes. In the present article, we present a bibliographical survey of several previously issued reports on chromosomal abnormalities associated with DWS, including our case of DWS found in trisomy 18. There are various types of chromosomal abnormalities associated with DWS; most of them are reported in chromosome 3, 9, 13 and 18. We also summarize some other chromosomal abnormalities and various congenital malformation syndromes.
Imataka
George
G
Department of Pediatrics, Dokkyo University School of Medicine, Tochigi, Japan. geo@dokkyomed.ac.jp
Yamanouchi
Hideo
H
Arisaka
Osamu
O
D002869:Chromosome Aberrations; D002875:Chromosomes; D003616:Dandy-Walker Syndrome / Q000209:etiology / Q000235:genetics*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D011247:Pregnancy; D016216:Ultrasonography, Prenatal