[Characterization and antimicrobial activity of the bioactive metabolites in streptomycete isolates].
Twenty different streptomycete isolates were obtained from soils of southeast Serbia. Five isolates identified as Streptomyces hygroscopicus (SH100, SH101, SH102, SH103, and SH104) showed strong activity against Botrytis cinerea, a parasite found in domestic vines. These isolates were extensively studied for their in vitro antimicrobial activity against Gram-positive bacteria, Gram-negative bacteria, yeasts and fungi, and also antiviral activity against Herpes simplex. The results indicated that the obtained isolates were highly active against Botrytis cinerea, Candida albicans, and Herpes simplex, with an inhibition zone of approximately 31 mm. The structure of the bioactive components was determined using elemental analysis, as well as UV/VIS, FTIR, and TLC.
Iliĉ
S B
SB
Konstantinoviĉ
S S
SS
Todoroviĉ
Z B
ZB
Laziĉ
M L
ML
Veljkoviĉ
V B
VB
Jokoviĉ
N
N
Radovanoviĉ
B C
BC
D000900:Anti-Bacterial Agents / Q000302:isolation & purification / Q000494:pharmacology; D000935:Antifungal Agents / Q000302:isolation & purification / Q000494:pharmacology; D000977:Antiparasitic Agents / Q000302:isolation & purification / Q000494:pharmacology; D000998:Antiviral Agents / Q000302:isolation & purification / Q000494:pharmacology; D020171:Botrytis / Q000187:drug effects / Q000254:growth & development; D002176:Candida albicans / Q000187:drug effects / Q000254:growth & development; D006090:Gram-Negative Bacteria / Q000187:drug effects / Q000254:growth & development; D006094:Gram-Positive Bacteria / Q000187:drug effects / Q000254:growth & development; D018139:Simplexvirus / Q000187:drug effects / Q000254:growth & development; D012988:Soil Microbiology; D013302:Streptomyces / Q000145:classification / Q000302:isolation & purification / Q000502:physiology*
D000900:Anti-Bacterial Agents; D000935:Antifungal Agents; D000977:Antiparasitic Agents; D000998:Antiviral Agents