title: Isotopic response of fungal granuloma following facial herpes zoster infections - report of three cases.
abstract: BACKGROUND
  An isotopic response is the occurrence of a new skin disease at the site of another unrelated, healed skin disorder.
  
  
  METHODS
  We report three cases of unilateral granulomatous fungal infection in immunocompetent patients at sites of resolved herpes zoster on the face. Diagnoses were made by potassium hydroxide preparation, histopathologic findings, and fungal culture. Two patients had Candida albicans folliculitis, and the other was infected with both Epidermophyton floccosum and Trichophyton mentagrophytes.
  
  
  RESULTS
  The patients responded well to antifungal therapy.
  
  
  CONCLUSIONS
  Localized isotopic fungal infections, although rare, can occur in immunocompetent patients.
authors.affiliation: Department of Dermatology, Mackay Memorial Hospital, Taipei, Taiwan.
authors.forename: Ching-Wen
authors.initials: CW
authors.lastname: Huang
authors.forename: Mei-Eng
authors.initials: ME
authors.lastname: Tu
authors.forename: Yu-Hung
authors.initials: YH
authors.lastname: Wu
authors.forename: Yang-Chih
authors.initials: YC
authors.lastname: Lin
mesh_terms: D000368:Aged; D002176:Candida albicans / Q000302:isolation & purification; D002179:Candidiasis, Cutaneous / Q000188:drug therapy / Q000209:etiology* / Q000382:microbiology / Q000473:pathology; D004821:Epidermophyton / Q000302:isolation & purification; D005148:Facial Dermatoses / Q000209:etiology* / Q000382:microbiology / Q000821:virology; D006099:Granuloma / Q000382:microbiology*; D006562:Herpes Zoster / Q000150:complications* / Q000188:drug therapy; D006801:Humans; D008297:Male; D008875:Middle Aged; D014005:Tinea / Q000188:drug therapy / Q000209:etiology* / Q000382:microbiology / Q000473:pathology; D014249:Trichophyton / Q000302:isolation & purification