title: Three new C21-steroidal glycosides from the roots of Cynanchum inamoenum.
abstract: Three new C(21)-steroidal glycosides presenting an unusual 13,14:14,15-disecopregnane-type skeleton, named inamosides A-C (1-3), together with two known C(21)-steroidal glycosides, were isolated from the MeOH extract of the roots of Cynanchum inamoeum (Maxim.) Loes (Asclepiadaceae). The aglycone of compounds 1, 2, and 3 has a 2beta-hydroxyl, which has not yet been reported in the literature. The structure and relative configuration of the aglycone of compounds 1, 2, and 3 were established by X-ray crystallographic analysis.
authors.affiliation: State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Kunming, China.
authors.forename: Li-Qin
authors.initials: LQ
authors.lastname: Wang
authors.forename: Yang
authors.initials: Y
authors.lastname: Lu
authors.forename: You-Xing
authors.initials: YX
authors.lastname: Zhao
authors.forename: Jun
authors.initials: J
authors.lastname: Zhou
authors.forename: Qi-Tai
authors.initials: QT
authors.lastname: Zheng
mesh_terms: D029062:Apocynaceae / Q000737:chemistry*; D018360:Crystallography, X-Ray; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D018517:Plant Roots / Q000737:chemistry*; D013256:Steroids / Q000737:chemistry / Q000302:isolation & purification*
chemical_list: D006027:Glycosides; D013256:Steroids