Primary peripheral adenoid cystic carcinoma of the lung and literature comparison of features.
Adenoid cystic carcinoma arising from the peripheral lung is rare. Here, we describe adenoid cystic carcinoma that developed in the peripherally in S(9) of the right lower lobe of an 84-year-old woman. Cell blocks prepared from the bronchial wash specimens exhibited the cribriform formation. An immunohistochemical examination of the surgically resected tumor revealed positive thyroid transcription factor-1 and c-kit staining. Exons 9 and 11 of c-kit in tumor cells were not mutated. We compared the clinical features of this patient with those of 10 others described in the English-language literature.
Yokouchi
Hiroshi
H
Department of Internal Medicine, Iwamizawa Rosai Hospital, Japan Labour Health and Welfare Organization, Iwamizawa, Japan. h-yokouchi@iwamizawah.rofuku.go.jp
Otsuka
Yoshinori
Y
Otoguro
Yuhei
Y
Takemoto
Norihiro
N
Ito
Kiyotaka
K
Uchida
Yoshikazu
Y
Okamoto
Kenzo
K
Nishimura
Masaharu
M
Kimura
Kiyonobu
K
Kaji
Hiroshi
H
D000369:Aged, 80 and over; D003528:Carcinoma, Adenoid Cystic / Q000175:diagnosis* / Q000601:surgery; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008175:Lung Neoplasms / Q000175:diagnosis* / Q000601:surgery; D014057:Tomography, X-Ray Computed