[From tradition to innovation: the search for novel therapeutic molecules to treat diabetes].
There are over a hundred chemical substances that have been derived from plants for use as drugs and medicines; many more await and medicinal plants are the target of all the attention. The structural diversity of natural products still surpasses that from synthetic compounds and is far beyond any imagination of experts in the field. For many pharmaceutical companies, it is a good argument to investigate natural compounds. Many plants with antidiabetic virtues are known in traditional medicine over the world. The CPID (Centre de Pharmacologie et Innovation dans le Diabète) proposes a technology program to purify new natural antidiabetic substances. A large antidiabetic plant library is constructed for a high-throughput pharmacological screening with cell cultures.
Tousch
Didier
D
Centre de Pharmacologie et Innovation dans le Diabète, Université Montpellier 1, UMR 5232 CNRS, Faculté de pharmacie, 15, avenue Charles Flahault, BP 14491, 34093 Montpellier Cedex 5, France. didier.tousch@univ-montp1.fr
D003920:Diabetes Mellitus / Q000188:drug therapy*; D006801:Humans; D007004:Hypoglycemic Agents / Q000138:chemical synthesis / Q000145:classification / Q000627:therapeutic use*; D007328:Insulin / Q000627:therapeutic use; D010600:Pharmacology; D010936:Plant Extracts / Q000627:therapeutic use; D010946:Plants, Medicinal
D007004:Hypoglycemic Agents; D007328:Insulin; D010936:Plant Extracts