[Relationship between serum HBV DNA levels and serum hyaluronic acid levels in hepatitis B cirrhosis patients].
OBJECTIVE
To probe the relationship between serum HBV DNA levels and serum hyaluronic acid (HA) levels in hepatitis B cirrhosis patients.


METHODS
Of 62 patients diagnosed with hepatitis B cirrhosis serum HBV DNA was determined by fluorescent quantitative PCR. Serum HA was determined by radioimmunity assay. The relationship between serum HBV DNA levels and serum HA levels was probed.


RESULTS
Serum HA of hepatitis B cirrhosis patients increased significantly and increased with the Child grade ascending (P less than 0.05). But serum HA levels had no significant correlation with serum HBV DNA levels (P greater than 0.05).


CONCLUSIONS
Serum HBV DNA levels had no significant correlation with liver cirrhosis grades and serum HA levels in hepatitis B cirrhosis patients.
Li
Hong-Yi
HY
Liver Research Center, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
Dong
Zhong
Z
Ma
Hong
H
D000328:Adult; D004279:DNA, Viral / Q000097:blood* / Q000235:genetics; D005260:Female; D006515:Hepatitis B virus / Q000235:genetics; D019694:Hepatitis B, Chronic / Q000150:complications*; D006801:Humans; D006820:Hyaluronic Acid / Q000097:blood*; D008103:Liver Cirrhosis / Q000097:blood* / Q000209:etiology; D008297:Male; D008875:Middle Aged; D016133:Polymerase Chain Reaction / Q000379:methods; D011863:Radioimmunoassay / Q000379:methods
D004279:DNA, Viral; D006820:Hyaluronic Acid