Repetitive transcranial magnetic stimulation of human MT+ reduces apparent motion perception.
We investigated the effects of repetitive transcranial magnetic stimulation (rTMS) over the human cerebral cortex on apparent motion perception. Previous studies have shown that human extrastriate visual area MT+ (V5) processes not only real but also apparent motion. However, the functional relevance of MT+ on long-range apparent motion perception remains unclear. Here, we show direct evidence for the involvement of MT+ in apparent motion perception using rTMS, which is known to temporarily inhibit a localized region in the cerebral cortex. The results showed that apparent motion perception decreased after applying rTMS over MT+, but not after applying rTMS over the control region (inferior temporal gyrus). The decrease in performance caused by applying rTMS to MT+ suggests that MT+ is a causally responsible region for apparent motion perception, and thus, further supports the idea that MT+ plays a major role in the perception of motion.
Matsuyoshi
Daisuke
D
Department of Psychology, Graduate School of Letters, Kyoto University, Yoshida-honmachi, Sakyo, Kyoto 606-8501, Japan. matsuyoshi@psy.mbox.media.kyoto-u.ac.jp
Hirose
Nobuyuki
N
Mima
Tatsuya
T
Fukuyama
Hidenao
H
Osaka
Naoyuki
N
D000328:Adult; D001931:Brain Mapping; D004292:Dominance, Cerebral / Q000502:physiology; D005260:Female; D006801:Humans; D008297:Male; D009039:Motion Perception / Q000502:physiology*; D009433:Neural Inhibition / Q000502:physiology; D009483:Neuropsychological Tests; D009778:Occipital Lobe / Q000033:anatomy & histology / Q000502:physiology*; D010468:Perceptual Disorders / Q000209:etiology / Q000503:physiopathology; D010775:Photic Stimulation; D013702:Temporal Lobe / Q000033:anatomy & histology / Q000502:physiology*; D050781:Transcranial Magnetic Stimulation / Q000009:adverse effects*; D014793:Visual Cortex / Q000033:anatomy & histology / Q000502:physiology*; D014795:Visual Pathways / Q000033:anatomy & histology / Q000502:physiology*