A new bufadienolide obtained from the biotransformation of cinobufagin by Alternaria alternata.
A new bufadienolide, 12-oxo-desacetylcinobufagin, was obtained from the biotransformation of cinobufagin by Alternaria alternata in fairly low yield (0.34%). Its structure was established on the basis of (1)H-NMR, (13)C-NMR, 2D-NMR, and MS spectral data.
Ye
Min
M
The State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, China.
Guo
Dean
D
D000528:Alternaria / Q000378:metabolism*; D002018:Bufanolides / Q000737:chemistry* / Q000378:metabolism*; D015394:Molecular Structure
D002018:Bufanolides; C087925:bufadienolide; C002471:cinobufagin