Chiral thiols: the assignment of their absolute configuration by 1H NMR.
A general NMR spectroscopy protocol for determination of absolute configuration of thiols, that includes the introduction of new aryl-tert-butoxyacetic acids as chiral derivatizing agents (CDAs), is described.
Porto
Silvia
S
Departamento de Química Orgánica, Facultad de Química y Unidad de RMN de Biomoléculas Asociada al CSIC, Universidad de Santiago de Compostela, E-15782 Santiago de Compostela, Spain.
Seco
José Manuel
JM
Ortiz
Aurelio
A
Quiñoá
Emilio
E
Riguera
Ricardo
R
D008024:Ligands; D009682:Magnetic Resonance Spectroscopy / Q000379:methods* / Q000592:standards*; D008968:Molecular Conformation; D011522:Protons; D012015:Reference Standards; D013237:Stereoisomerism; D013438:Sulfhydryl Compounds / Q000737:chemistry*
D008024:Ligands; D011522:Protons; D013438:Sulfhydryl Compounds