title: New formation of imines of C19-diterpenoid alkaloids by heating with DMSO.
abstract: Treatment of some C(19)-diterpenoid alkaloids (3, 6, 10 and 12) with anhydrous DMSO at 100-170 degrees C for 3-7 h led to the formation of the corresponding imines (4, 7/8, 11, 13/14) in 65-83% yield, respectively. This is a new simpler formation of the imines of the C(19)-diterpenoid alkaloids.
authors.affiliation: Department of Chemistry of Medicinal Natural Products, West China College of Pharmacy, Sichuan University, Chengdu, China.
authors.forename: Ya-Mei
authors.initials: YM
authors.lastname: He
authors.forename: Chun-Lan
authors.initials: CL
authors.lastname: Zou
authors.forename: Qiao-Hong
authors.initials: QH
authors.lastname: Chen
authors.forename: Feng-Peng
authors.initials: FP
authors.lastname: Wang
mesh_terms: D000470:Alkaloids / Q000737:chemistry*; D004121:Dimethyl Sulfoxide / Q000737:chemistry*; D004224:Diterpenes / Q000737:chemistry*; D007097:Imines / Q000138:chemical synthesis*; D021241:Spectrometry, Mass, Electrospray Ionization
chemical_list: D000470:Alkaloids; D004224:Diterpenes; D007097:Imines; D004121:Dimethyl Sulfoxide