title: Role of polysaccharides in Pseudomonas aeruginosa biofilm development.
abstract: During the past decade, there has been a renewed interest in using Pseudomonas aeruginosa as a model system for biofilm development and pathogenesis. Since the biofilm matrix represents a crucial interface between the bacterium and the host or its environment, considerable effort has been expended to acquire a more complete understanding of the matrix composition. Here, we focus on recent developments regarding the roles of alginate, Psl, and Pel polysaccharides in the biofilm matrix.
authors.affiliation: Department of Microbiology and Immunology, Wake Forest University School of Medicine, Medical Center Boulevard, Winston-Salem, NC 27157-1064, United States.
authors.forename: Cynthia
authors.initials: C
authors.lastname: Ryder
authors.forename: Matthew
authors.initials: M
authors.lastname: Byrd
authors.forename: Daniel J
authors.initials: DJ
authors.lastname: Wozniak
mesh_terms: D000464:Alginates / Q000378:metabolism; D001426:Bacterial Proteins / Q000235:genetics / Q000378:metabolism*; D018441:Biofilms / Q000254:growth & development*; D005109:Extracellular Matrix / Q000378:metabolism; D015964:Gene Expression Regulation, Bacterial; D006801:Humans; D011135:Polysaccharides, Bacterial / Q000378:metabolism*; D011550:Pseudomonas aeruginosa / Q000235:genetics / Q000254:growth & development* / Q000378:metabolism
chemical_list: D000464:Alginates; D001426:Bacterial Proteins; D011135:Polysaccharides, Bacterial; C064841:exopolysaccharide, Pseudomonas