title: Fat loss depends on energy deficit only, independently of the method for weight loss.
abstract: BACKGROUND
  This study was designed to compare the effects of 2 different but isocaloric fat reduction programs with the same amount of energy deficit - diet alone or diet combined with aerobic training - on body composition, lipid profile and cardiorespiratory fitness in non- or moderately obese women.
  
  
  METHODS
  Twenty non- or moderately obese (BMI 24.32 +/- 3.11) females (27.3 +/- 6.6 years) were tested at the beginning and after an 8-week period of a mild hypocaloric diet for the following parameters: (1) body mass and body fat; (2) total cholesterol, HDL-C, LDL-C and triglycerides; (3) lactate (millimol/liter) during submaximal exertion (100 W); (4) heart rate during submaximal exertion (100 W), and (5) maximum exercise performance (watt). Subjects were randomly divided into either a diet alone (D, -2,095 +/- 659 kJ/day) or a diet (-1,420 +/- 1,084 kJ/day) plus exercise (DE, three 60-min sessions per week at 60% of VO(2)max or -5,866 kJ/week) group.
  
  
  RESULTS
  Body mass and body fat decreased significantly in D (-1.95 +/- 1.13 kg or -1.47 +/- 0.87%; p < 0.05) and DE (-2.23 +/- 1.28 kg or -1.59 +/- 0.87%; p < 0.05), but there was no significant difference observed between the groups. Statistical analysis revealed no significant changes of total cholesterol, HDL-C, LDL-C, triglycerides and heart rate during submaximal exertion (100 W). Lactic acid accumulation during submaximal exertion (100 W) decreased significantly (-0.8 +/- 1.4 mmol/l, p < 0.05) in DE and increased significantly (+0.4 +/- 0.5 mmol/l, p < 0.05) in D. Maximum exercise performance improved significantly (+12.2 +/- 8.8 W, p < 0.05) in DE and did not change significantly in D.
  
  
  CONCLUSIONS
  This study showed that independently of the method for weight loss, the negative energy balance alone is responsible for weight reduction.
authors.affiliation: Department of Internal Medicine IV, Division of Sports Medicine, Medical University Vienna, Vienna, Austria. barbara.strasser@trainingstherapie.at
authors.forename: B
authors.initials: B
authors.lastname: Strasser
authors.forename: A
authors.initials: A
authors.lastname: Spreitzer
authors.forename: P
authors.initials: P
authors.lastname: Haber
mesh_terms: D000273:Adipose Tissue; D000328:Adult; D001823:Body Composition / Q000502:physiology*; D015992:Body Mass Index; D003131:Combined Modality Therapy; D018752:Diet, Fat-Restricted; D004038:Diet, Reducing; D015444:Exercise / Q000502:physiology*; D005260:Female; D006339:Heart Rate / Q000502:physiology; D006801:Humans; D007773:Lactates / Q000378:metabolism; D050356:Lipid Metabolism / Q000502:physiology; D050177:Overweight / Q000178:diet therapy / Q000628:therapy*; D010101:Oxygen Consumption; D016896:Treatment Outcome; D015431:Weight Loss / Q000502:physiology
chemical_list: D007773:Lactates