title: Diet with LPP for renal patients increases daily energy expenditure and improves motor function in parkinsonian patients with motor fluctuations.
abstract: OBJECTIVE
  To establish whether a diet based on the usage of low-protein products for renal patients (LPP) is associated with higher energy expenditure (EE) than a free low-protein diet (NO-LPP) by calculating 24 h EE by indirect calorimetry using an electronic armband monitor.
  
  
  METHODS
  Randomized, cross-over, single-blind, pilot clinical trial performed comparing two different low-protein dietary regimens.
  
  
  METHODS
  Forty-two days with LPP and 42 days with NO-LPP regimen in six patients with Parkinson's disease with levodopa.
  
  
  METHODS
  Monitoring patient response to two different nutritional schemes through indirect calorimetry (armband), BMI, Patient Global Improvement Scale.
  
  
  RESULTS
  Mean total EE was 1731 +/- 265 kcal/day with NO-LPP vs. 1903 +/- 265 kcal/day with LPP (p = 0.02).
  
  
  CONCLUSIONS
  The usage of LPP increases EE and improves motor function in PD patients to a greater extent than NO-LPP dietary regimen. Calorie intake should be increased to prevent malnutrition in the long-term.
authors.affiliation: Parkinson Institute, Istituti Clinici di Perfezionamento, Milan, Italy. barichella@parkinson.it
authors.forename: Michela
authors.initials: M
authors.lastname: Barichella
authors.forename: Chiara
authors.initials: C
authors.lastname: Savardi
authors.forename: Andrea
authors.initials: A
authors.lastname: Mauri
authors.forename: Agnieszka
authors.initials: A
authors.lastname: Marczewska
authors.forename: Antonella
authors.initials: A
authors.lastname: Vairo
authors.forename: Cinzia
authors.initials: C
authors.lastname: Baldo
authors.forename: Arianna
authors.initials: A
authors.lastname: Massarotto
authors.forename: Sara Elisabetta
authors.initials: SE
authors.lastname: Cordara
authors.forename: Gianni
authors.initials: G
authors.lastname: Pezzoli
mesh_terms: D017668:Age of Onset; D000368:Aged; D002151:Calorimetry; D018592:Cross-Over Studies; D018753:Diet, Protein-Restricted; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009043:Motor Activity / Q000502:physiology*; D010300:Parkinson Disease / Q000178:diet therapy* / Q000503:physiopathology*; D010865:Pilot Projects; D051437:Renal Insufficiency / Q000178:diet therapy* / Q000503:physiopathology; D016037:Single-Blind Method