A comparison of microwave-accelerated and conventionally heated iodination reactions of some arenes and heteroarenes, using ortho-periodic acid as the oxidant.
A fast and simple method for the oxidative iodination of some activated arenes and heteroarenes, either under microwave irradiation or by conventional heating, is reported, using diiodine and ortho-periodic acid as the oxidant. The reactions were carried out in hot 95% ethanol under a reflux condenser. For the microwave assisted reactions, the reaction times were always notably shortened, but the yields were nearly the same as those afforded by the conventional method.
Sosnowski
Maciej
M
Chair and Laboratory of Organic Chemistry, Faculty of Pharmacy, Medical University, 1 Banacha Street, PL 02-097 Warsaw, Poland.
Skulski
Lech
L
D002384:Catalysis / Q000187:drug effects / Q000528:radiation effects; D004526:Efficiency; D054879:Halogenation / Q000528:radiation effects*; D006571:Heterocyclic Compounds / Q000737:chemistry / Q000528:radiation effects; D006358:Hot Temperature; D008872:Microwaves; D009281:Naphthalenes / Q000737:chemistry* / Q000528:radiation effects; D016877:Oxidants / Q000494:pharmacology; D010504:Periodic Acid / Q000494:pharmacology*
D006571:Heterocyclic Compounds; D009281:Naphthalenes; D016877:Oxidants; D010504:Periodic Acid