Metal ion promoted cleavage of RNA phosphodiester bonds: from Zn(II) aqua ion to artificial ribonucleases.
The potential of Zn(2+) azacrown chelates as constituents of artificial ribonucleases is discussed.
Wang
Qi
Q
Department of Chemistry, University of Turku, FIN-20014 Turku, Finland.
Niittymäki
Teija
T
Virta
Pasi
P
Ketomäki
Kaisa
K
Mikkola
Satu
S
Lönnberg
Harri
H
D002384:Catalysis; D047248:Crown Compounds / Q000737:chemistry*; D009942:Organometallic Compounds / Q000737:chemistry*; D010710:Phosphates / Q000737:chemistry; D012260:Ribonucleases / Q000737:chemistry*; D015032:Zinc / Q000737:chemistry*
C511821:1,5,9-triazacyclododecane (12(ane)N3) Zn(II); D047248:Crown Compounds; D009942:Organometallic Compounds; D010710:Phosphates; D012260:Ribonucleases; D015032:Zinc