title: Nationwide study of the prevalence, characteristics, and molecular epidemiology of extended-spectrum-beta-lactamase-producing Enterobacteriaceae in France.
abstract: Among 10,872 isolates of Enterobacteriaceae from a nationwide study of 88 French hospitals in 2005, 169 (1.7%) expressed an extended-spectrum beta-lactamase. The most prevalent species were Escherichia coli (48.5%), Enterobacter aerogenes (23.7%), and Klebsiella pneumoniae (14.8%). Molecular analysis underlined the polyclonal spread of CTX-M-expressing E. coli, primarily isolates of the CTX-M-1 subgroup.
authors.affiliation: Service d'Hygiène Hospitalière, Centre Hospitalier de Versailles, Le Chesnay, France.
authors.forename: Muriel
authors.initials: M
authors.lastname: Galas
authors.forename: Jean-Winoc
authors.initials: JW
authors.lastname: Decousser
authors.forename: Nelly
authors.initials: N
authors.lastname: Breton
authors.forename: Thierry
authors.initials: T
authors.lastname: Godard
authors.forename: Pierre Yves
authors.initials: PY
authors.lastname: Allouch
authors.forename: Patrick
authors.initials: P
authors.lastname: Pina
mesh_terms: D004755:Enterobacteriaceae / Q000145:classification / Q000187:drug effects / Q000201:enzymology* / Q000235:genetics; D004756:Enterobacteriaceae Infections / Q000453:epidemiology* / Q000382:microbiology; D004926:Escherichia coli / Q000201:enzymology / Q000235:genetics; D005602:France / Q000453:epidemiology; D008826:Microbial Sensitivity Tests; D017720:Molecular Epidemiology; D015995:Prevalence; D018440:beta-Lactam Resistance; D001618:beta-Lactamases / Q000096:biosynthesis* / Q000145:classification / Q000235:genetics; D047090:beta-Lactams
chemical_list: D047090:beta-Lactams; C055184:beta-lactamase TEM-3; D001618:beta-Lactamases