Synthesis of 4-amino-4,5-dihydro-1H-1,2,4-triazole-5-ones and their isatin-3-imine derivatives.
Iminoester hydrochlorides 1 have been synthesized. These compounds were then converted into ester ethoxycarbonyl hydrazones 2, from which in turn a new series of substituted 4-amino-4,5-dihydro-1H-1,2,4-triazole-5-ones, 3, was then prepared. Finally a set of isatin imine derivatives 4 was obtained from the reaction of compounds 3 with isatin. The structures of all the new synthesized compounds were confirmed by elemental analyses, IR, (1)H-NMR and (13)C-NMR spectra.
Kahveci
Bahittin
B
Department of Chemistry, Rize Faculty of Arts and Science, Karadeniz Technical University, 53100, Rize, Turkey. bahittin@yahoo.com
D007097:Imines / Q000138:chemical synthesis*; D007510:Isatin / Q000031:analogs & derivatives* / Q000737:chemistry*; D008954:Models, Biological; D014230:Triazoles / Q000138:chemical synthesis*
D007097:Imines; D014230:Triazoles; D007510:Isatin