title: Guidelines for the management of pregnancy in women with cystic fibrosis.
abstract: Women with cystic fibrosis (CF) now regularly survive into their reproductive years in good health and wish to have a baby. Many pregnancies have been reported in the literature and it is clear that whilst the outcome for the baby is generally good and some mothers do very well, others find either their CF complicates the pregnancy or is adversely affected by the pregnancy. For some, pregnancy may only become possible after transplantation. Optimal treatment of all aspects of CF needs to be maintained from the preconceptual period until after the baby is born. Clinicians must be prepared to modify their treatment to accommodate the changing physiology during pregnancy and to be aware of changing prescribing before conception, during pregnancy, after birth and during breast feeding. This supplement offers consensus guidelines based on review of the literature and experience of paediatricians, adult and transplant physicians, and nurses, physiotherapists, dietitians, pharmacists and psychologists experienced in CF and anaesthetist and obstetricians with experience of CF pregnancy. It is hoped they will provide practical guidelines helpful to the multidisciplinary CF teams caring for pregnant women with CF.
authors.affiliation: Adult CF Centre, Northern General Hospital, Herries Road, Sheffield, S5 7AU, UK. Frank.edenborough@sth.nhs.uk
authors.forename: F P
authors.initials: FP
authors.lastname: Edenborough
authors.forename: G
authors.initials: G
authors.lastname: Borgo
authors.forename: C
authors.initials: C
authors.lastname: Knoop
authors.forename: L
authors.initials: L
authors.lastname: Lannefors
authors.forename: W E
authors.initials: WE
authors.lastname: Mackenzie
authors.forename: S
authors.initials: S
authors.lastname: Madge
authors.forename: A M
authors.initials: AM
authors.lastname: Morton
authors.forename: H C
authors.initials: HC
authors.lastname: Oxley
authors.forename: D J
authors.initials: DJ
authors.lastname: Touw
authors.forename: M
authors.initials: M
authors.lastname: Benham
authors.forename: M
authors.initials: M
authors.lastname: Johannesson
mesh_terms: D000014:Abnormalities, Drug-Induced / Q000517:prevention & control; D000028:Abortion, Induced; D001942:Breast Feeding; D003376:Counseling; D003550:Cystic Fibrosis / Q000523:psychology / Q000628:therapy*; D036861:Delivery, Obstetric; D005260:Female; D005817:Genetic Counseling; D006801:Humans; D009732:Nursing Care; D044623:Nutrition Therapy; D016377:Organ Transplantation; D010347:Patient Care Planning; D011181:Postnatal Care; D016742:Preconception Care; D011247:Pregnancy; D011248:Pregnancy Complications / Q000523:psychology / Q000628:therapy*; D011295:Prenatal Care