title: Pechmann reaction promoted by boron trifluoride dihydrate.
abstract: The Pechmann reaction of substituted phenols 1a-e with methyl acetoacetate (2) can be activated by boron trifluoride dihydrate (3) to give the corresponding 4-methyl- coumarin derivatives 4a-e in excellent yield (98-99 %).
authors.affiliation: Faculty of Pharmacy, Medical University of Sofia, Dunav 2, BG-1000 Sofia, Bulgaria. estoyanov@yahoo.com
authors.forename: Edmont V
authors.initials: EV
authors.lastname: Stoyanov
authors.forename: Jochen
authors.initials: J
authors.lastname: Mezger
mesh_terms: D001555:Benzene Derivatives / Q000737:chemistry; D001880:Boranes / Q000737:chemistry*; D003374:Coumarins / Q000737:chemistry*; D007202:Indicators and Reagents; D007700:Kinetics; D010636:Phenols / Q000737:chemistry*; D013816:Thermodynamics; D014867:Water
chemical_list: D001555:Benzene Derivatives; D001880:Boranes; D003374:Coumarins; D007202:Indicators and Reagents; D010636:Phenols; D014867:Water; C021274:boron trifluoride