title: Vicinal amino alcohols as organocatalysts in asymmetric cross-aldol reaction of ketones: application in the synthesis of convolutamydine A.
abstract: Leucinol and valinol have been identified as efficient organocatalysts for the aldol reaction of isatin and its derivatives (as examples of activated, non-enolizable ketones) with acetone. Uncommon mechanistic features were observed and used in the formulation of the transition state of the reaction.
authors.affiliation: Department of Chemistry, Joseph Black Building, WestChem, University of Glasgow, Glasgow G12 8QQ, Scotland, UK. amalkov@chem.gla.ac.uk
authors.forename: Andrei V
authors.initials: AV
authors.lastname: Malkov
authors.forename: Mikhail A
authors.initials: MA
authors.lastname: Kabeshov
authors.forename: Marco
authors.initials: M
authors.lastname: Bella
authors.forename: Ondrej
authors.initials: O
authors.lastname: Kysilka
authors.forename: Denis A
authors.initials: DA
authors.lastname: Malyshev
authors.forename: Kristýna
authors.initials: K
authors.lastname: Pluhácková
authors.forename: Pavel
authors.initials: P
authors.lastname: Kocovský