title: [Hodgkin's disease presenting with spinal cord compression].
abstract: BACKGROUND
  Hematological neoplasms may be complicated by signs of neurological compression. Most cases reported in the literature have described advanced-stage non-Hodgkin lymphomas. We report a case of spinal cord compression revealing an isolated vertebral localization of Hodgkin lymphoma.
  
  
  METHODS
  Magnetic resonance imaging of the thoracic spine in a 54-year-old man who presented with spastic paraplegia revealed a vertebral and extradural mass. After laminectomy, histology and immunohistochemistry showed Hodgkin's disease. Post-operative staging did not reveal any other localization. The patient responded favorably after decompressive surgery and ABVD regimen.
  
  
  CONCLUSIONS
  Spinal cord compression is a rare complication of Hodgkin's disease, occurring in only 5p.cent of cases, usually in the setting of progressive, advanced disease. As the initial symptom of Hodgkin's disease, it is extremely rare, with only a few cases reported in the literature. Significant results may be obtained with decompressive surgery and chemotherapy when the disease is promptly diagnosed. Spinal cord compression by primary Hodgkin's disease is a very infrequent situation. We urge this diagnosis be considered in all patients presenting with spinal cord compression attributed to malignancy.
authors.affiliation: Service de Médecine "A", Hôpital Militaire d'Instruction Mohammed V, Rabat, Maroc. m_rabhi@menara.ma
authors.forename: M
authors.initials: M
authors.lastname: Rabhi
authors.forename: K
authors.initials: K
authors.lastname: Ennibi
authors.forename: J
authors.initials: J
authors.lastname: Chaari
authors.forename: F
authors.initials: F
authors.lastname: Toloune
mesh_terms: D019299:Decompression, Surgical; D005682:Gadolinium; D006689:Hodgkin Disease / Q000150:complications* / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D007150:Immunohistochemistry; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D020336:Paraparesis, Spastic / Q000209:etiology / Q000473:pathology; D013116:Spinal Cord / Q000473:pathology; D013117:Spinal Cord Compression / Q000209:etiology* / Q000473:pathology / Q000601:surgery
chemical_list: D005682:Gadolinium