title: Pertussis and respiratory syncytial virus infections.
abstract: During the winter 2005-2006, all infants <4 months of age admitted for bronchiolitis or acute respiratory tract infection in a tertiary care pediatric hospital in Paris were tested for respiratory syncytial virus (RSV) and pertussis with real-time polymerase-chain reaction (RT-PCR). A positive pertussis-PCR was found in 14/90 (16%) infants infected with RSV and in 5/30 negative for RSV. Similar clinical symptoms were found in all RSV-positive infants with or without pertussis co-infection. Most infants (73%) were not vaccinated against pertussis, and the other children had received one or two injections. In conclusion, pertussis-RSV co-infection is common in young infants, and pertussis-PCR should be used, whenever available.
authors.affiliation: Department of Pediatric and Emergency, Université Paris 5, APHP, Hôpital Saint Vincent de Paul-Cochin, Paris, France.
authors.forename: Cécile
authors.initials: C
authors.lastname: Cosnes-Lambe
authors.forename: Josette
authors.initials: J
authors.lastname: Raymond
authors.forename: Martin
authors.initials: M
authors.lastname: Chalumeau
authors.forename: Charlotte
authors.initials: C
authors.lastname: Pons-Catalano
authors.forename: Florence
authors.initials: F
authors.lastname: Moulin
authors.forename: Nathalie
authors.initials: N
authors.lastname: de Suremain
authors.forename: Hélène
authors.initials: H
authors.lastname: Reglier-Poupet
authors.forename: Pierre
authors.initials: P
authors.lastname: Lebon
authors.forename: Claire
authors.initials: C
authors.lastname: Poyart
authors.forename: Dominique
authors.initials: D
authors.lastname: Gendrel
mesh_terms: D005260:Female; D006776:Hospitals, Pediatric; D006801:Humans; D007223:Infant; D008297:Male; D010297:Paris / Q000453:epidemiology; D010567:Pertussis Vaccine / Q000008:administration & dosage; D015995:Prevalence; D011446:Prospective Studies; D018357:Respiratory Syncytial Virus Infections / Q000150:complications* / Q000453:epidemiology; D012136:Respiratory Syncytial Viruses / Q000302:isolation & purification*; D020133:Reverse Transcriptase Polymerase Chain Reaction; D014917:Whooping Cough / Q000150:complications* / Q000453:epidemiology / Q000517:prevention & control
chemical_list: D010567:Pertussis Vaccine