title: Lung function in subjects exposed to crude oil spill into sea water.
abstract: A Greek oil-tanker ran aground, resulting in a huge oil spill along the costal areas of Karachi, Pakistan. The purpose of this study was to assess the lung function and follow up change after one year in subjects exposed to crude oil spill in sea water. It was a cross sectional study with follow up in 20 apparently healthy, non-smoking, male workers, who were exposed to a crude oil spill environment during oil cleaning operation. The exposed group was matched with 31 apparently healthy male control subjects. Pulmonary function test was performed using an electronic Spirometer. Subjects exposed to polluted air have significant reduction in forced vital capacity (FVC), forced expiratory volume in first second (FEV(1)), forced expiratory flow (FEF(25-75%)) and maximum voluntary ventilation (MVV) compared to their matched controls. This impairment was reversible and lung functions parameters were improved when the subjects were withdrawn from the polluted air environment.
authors.affiliation: Department of Physiology, College of Medicine, King Saud University, P.O. Box 2925, Riyadh 11461, Saudi Arabia. sultanmeo@hotmail.com
authors.forename: Sultan Ayoub
authors.initials: SA
authors.lastname: Meo
authors.forename: Abdul Majeed
authors.initials: AM
authors.lastname: Al-Drees
authors.forename: Imran M U
authors.initials: IM
authors.lastname: Meo
authors.forename: Muslim M
authors.initials: MM
authors.lastname: Al-Saadi
authors.forename: Muhammad Abdul
authors.initials: MA
authors.lastname: Azeem
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D004190:Disasters; D004781:Environmental Exposure; D005541:Forced Expiratory Volume; D006801:Humans; D008168:Lung / Q000503:physiopathology*; D008297:Male; D008451:Maximal Voluntary Ventilation; D008875:Middle Aged; D009792:Oceans and Seas; D010154:Pakistan; D010578:Petroleum / Q000009:adverse effects*; D012140:Respiratory Tract Diseases / Q000139:chemically induced* / Q000503:physiopathology; D013147:Spirometry; D014797:Vital Capacity; D014874:Water Pollutants, Chemical / Q000009:adverse effects*
chemical_list: D010578:Petroleum; D014874:Water Pollutants, Chemical