The Lutzomyia longipalpis species complex: does population sub-structure matter to Leishmania transmission?
Leishmania chagasi causes visceral leishmaniasis and, to a lesser extent, atypical cutaneous leishmaniasis in Central and South America. Its main sand fly vector, Lutzomyia longipalpis s.l. (Diptera: Psychodidae) displays a complex population structure that might contribute to the observed clinical pleomorphism and to recent major urban epidemics. This article summarises our understanding on reproductive barriers and hybridisation among this vector's sibling incipient species. Identifying genes important for sand fly ecological adaptability and sand fly-Leishmania genetic co-variation could be helpful for interrupting Leishmania transmission.
Maingon
Rhayza D C
RD
Centre for Applied Entomology and Parasitology, Institute of Science & Technology in Medicine, Keele University, Huxley Building, Staffordshire, ST5 5BG, UK.
Ward
Richard D
RD
Hamilton
James G C
JG
Bauzer
Luiz G S R
LG
Peixoto
Alexandre A
AA
D000818:Animals; D004463:Ecology; D019143:Evolution, Molecular; D005260:Female; D014644:Genetic Variation; D007303:Insect Vectors / Q000235:genetics / Q000469:parasitology / Q000502:physiology*; D018314:Leishmania infantum / Q000235:genetics / Q000472:pathogenicity; D007898:Leishmaniasis, Visceral / Q000635:transmission*; D008297:Male; D011576:Psychodidae / Q000235:genetics / Q000469:parasitology / Q000502:physiology*; D012724:Sex Attractants / Q000502:physiology
D012724:Sex Attractants