title: [Severe advanced lower gingival carcinoma effectively reduced by chemoradiation with S-1--report of a case].
abstract: Severe advanced head and neck carcinoma which can not be removed via surgical procedure combined with a large lymph node metastasis has a poor prognosis. We administered concurrent chemoradiotherapy with S-1 for a lower gingival carcinoma. As a direct result, we discovered that the treatment greatly reduced the size of tumor, and we consider that this treatment prolonged the patient.s life. The treatment results suggest that the so-called dormancy state of the tumor was continued. In this case study, radiotherapy with S-1 showed a highly effective response from the viewpoint of QOL improvement.
authors.affiliation: The First Dept. of Oral and Maxillofacial Surgery, Osaka University Graduate School of Dentistry.
authors.forename: Miki
authors.initials: M
authors.lastname: Ishibashi
authors.forename: Norio
authors.initials: N
authors.lastname: Masuda
authors.forename: Kazuma
authors.initials: K
authors.lastname: Noguchi
authors.forename: Kuniyasu
authors.initials: K
authors.lastname: Moridera
authors.forename: Norihiko
authors.initials: N
authors.lastname: Nishimura
authors.forename: Tomoyoshi
authors.initials: T
authors.lastname: Takayama
authors.forename: Kenichi
authors.initials: K
authors.lastname: Nishioji
authors.forename: Masahiro
authors.initials: M
authors.lastname: Urade
authors.forename: Mikihiko
authors.initials: M
authors.lastname: Kogo
mesh_terms: D000964:Antimetabolites, Antineoplastic / Q000008:administration & dosage*; D002294:Carcinoma, Squamous Cell / Q000188:drug therapy* / Q000532:radiotherapy*; D003131:Combined Modality Therapy; D004334:Drug Administration Schedule; D004338:Drug Combinations; D005887:Gingival Neoplasms / Q000188:drug therapy* / Q000532:radiotherapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010094:Oxonic Acid / Q000008:administration & dosage*; D011788:Quality of Life; D011879:Radiotherapy Dosage; D005641:Tegafur / Q000008:administration & dosage*
chemical_list: D000964:Antimetabolites, Antineoplastic; D004338:Drug Combinations; C079198:S 1 (combination); D005641:Tegafur; D010094:Oxonic Acid