Fragrance material review on 4-(1,2-epoxy-2,6,6-trimethylcyclohexyl)-3-buten-2-one.
A toxicologic and dermatologic review of 4-(1,2-epoxy-2,6,6-trimethylcyclohexyl)-3-buten-2-one when used as a fragrance ingredient is presented.
Lalko
J
J
Research Institute for Fragrance Materials, Inc., 50 Tice Boulevard, Woodcliff Lake, NJ 07677, USA.
Lapczynski
A
A
McGinty
D
D
Bhatia
S
S
Letizia
C S
CS
Api
A M
AM
D002073:Butanes / Q000145:classification / Q000493:pharmacokinetics / Q000633:toxicity*; D003257:Consumer Product Safety; D003510:Cyclohexanes / Q000145:classification / Q000493:pharmacokinetics / Q000633:toxicity*; D004305:Dose-Response Relationship, Drug; D006801:Humans; D009152:Mutagenicity Tests; D009153:Mutagens / Q000145:classification / Q000493:pharmacokinetics / Q000633:toxicity*; D010476:Perfume / Q000145:classification / Q000493:pharmacokinetics / Q000633:toxicity*; D018570:Risk Assessment; D012486:Salmonella typhimurium / Q000187:drug effects / Q000235:genetics; D012867:Skin / Q000187:drug effects / Q000378:metabolism; D012869:Skin Absorption
C526429:4-(1,2-epoxy-2,6,6-trimethylcyclohexyl)-3-buten-2-one; D002073:Butanes; D003510:Cyclohexanes; D009153:Mutagens; D010476:Perfume