Phthalimides as exceptionally efficient single electron transfer acceptors in reductive coupling reactions promoted by samarium diiodide.
Experimental and theoretical evidence shows that phthalimides are highly efficient single electron transfer acceptors in reactions promoted by samarium diiodide, affording ketyl radical anion intermediates, which participate in high-yielding inter- and intramolecular reductive coupling processes with different radicophiles including imides, oxime ethers, nitrones, and Michael acceptors.
Vacas
Tatiana
T
Instituto de Química OrgAnica General, CSIC, Juan de la Cierva, 3, E-28006 Madrid, Spain.
Alvarez
Eleuterio
E
Chiara
Jose Luis
JL