title: Microfluidic module system with piezo driven microvalve for synthesis of radiopharmaceutical products.
abstract: This article presents a novel microfluidic module system for the synthesis of radiopharmaceutical products. As a main function a piezo-actuated diaphragm valve is produced with rapid prototyping procedures. A system for the automatic characterization of microvalves is described. The built microvalve is characterized by a very high throughput and low leakage rate even for gaseous media. The valve as other passive modules like mixer elements can be easily combined to a microfluidic system. The system makes the application of radiopharmaceutical products more effective and less costly intensive.
authors.affiliation: MIMED Department of Micro Technology and Medical Device Engineering, Boltzmannstr. 15, D- 85748 Garching. scheuenpflug@tum.de
authors.forename: Michael
authors.initials: M
authors.lastname: Scheuenpflug
authors.forename: Daniel
authors.initials: D
authors.lastname: Guenther
authors.forename: Franz
authors.initials: F
authors.lastname: Irlinger
authors.forename: Tim
authors.initials: T
authors.lastname: Lueth
mesh_terms: D002626:Chemistry, Pharmaceutical / Q000295:instrumentation* / Q000379:methods; D004867:Equipment Design; D019544:Equipment Failure Analysis; D044085:Microfluidics / Q000295:instrumentation* / Q000379:methods; D004364:Pharmaceutical Preparations / Q000138:chemical synthesis*; D013678:Technology, Pharmaceutical / Q000295:instrumentation* / Q000379:methods; D014732:Vibration
chemical_list: D004364:Pharmaceutical Preparations