[Follow-up after surgical treatment of patients with familial adenomatous polyposis: results in a southern Spanish population].
OBJECTIVE
The study was to assess changes in the rectal mucosa and pouch in a series of patients with familial adenomatous polyposis (FAP) who underwent either subtotal colectomy and ileorectal anastomosis (IRA) or proctocolectomy and ileal pouch-anal anastomosis (IPAA), and to evaluate the suitability of the follow-up interval and postoperative treatment employed to prevent the development of cancer.


METHODS
This study involved 28 patients with FAP who underwent IRA (n=20) or IPAA (n=8), and were followed endoscopically over a mean period of 7.47 years. The number and both macroscopic and histological features of polyps before and after surgery, the treatment, and complications were all analyzed. The suitability of the follow-up interval was assessed.


RESULTS
None of the 26 patients who complied with follow-up developed rectal cancer. Two patients developed rectal cancer at 21 and 36 months after withdrawing from the protocol. Except in two cases in which surgery was indicated, patients who developed adenomas during follow-up were treated by endoscopic polypectomy.


CONCLUSIONS
In our series, the failure to comply with follow-up examinations was associated with cancer development.
Cordero Fernández
C
C
Servicio de Aparato Digestivo, Hospital Universitario Virgen del Rocío, Sevilla, Spain. carmenc@inicia.es
Pizarro Moreno
A
A
Garzón Benavides
M
M
García-Lozano
R
R
Belda Laguna
O
O
Sobrino
S
S
Bozada
J M
JM
Zulueta Dorado
T
T
D011125:Adenomatous Polyposis Coli / Q000601:surgery*; D000293:Adolescent; D000328:Adult; D001003:Anal Canal / Q000601:surgery; D000714:Anastomosis, Surgical; D039021:Colonic Pouches; D013505:Digestive System Surgical Procedures / Q000379:methods; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007082:Ileum / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D012007:Rectum / Q000601:surgery*; D013030:Spain