title: Immunological response in cases of complicated and uncomplicated bartonellosis during pregnancy.
abstract: Bartonellosis (Carrion's Disease) during pregnancy is associated with high rates of maternal and perinatal mortality. We report the immunological patterns in two cases of human bartonellosis during pregnancy. One patient had an uncomplicated course while the second patient developed life threatening anasarca and cardiac tamponade. The patient with a complicated course had a Th1 response with a higher elevation of IL-10. This elevation has been associated with poor outcome pregnancies during bacterial infections.
authors.affiliation: Department of Family & Community Medicine, University of New Mexico, Albuquerque, NM 87131-0001, USA. ehuarcaya@salud.unm.edu
authors.forename: Erick
authors.initials: E
authors.lastname: Huarcaya
authors.forename: Ciro
authors.initials: C
authors.lastname: Maguina
authors.forename: Ivan
authors.initials: I
authors.lastname: Best
authors.forename: Nelson
authors.initials: N
authors.lastname: Solorzano
authors.forename: Lawrence
authors.initials: L
authors.lastname: Leeman
mesh_terms: D000208:Acute Disease; D000328:Adult; D001474:Bartonella Infections / Q000276:immunology*; D016516:CD4-CD8 Ratio; D016207:Cytokines / Q000276:immunology*; D005260:Female; D006801:Humans; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000276:immunology / Q000382:microbiology*
chemical_list: D016207:Cytokines