A new kaempferol triglycoside from Fagonia taeckholmiana: cytotoxic activity of its extracts.
In addition to apigenin, apigenin 7-O-glucoside, kaempferol 3-O-glucoside, kaempferol 3,7-di-O-rhamnoside, quercetin, and quercetin 3-O-glucoside, the methanolic extract of Fagonia taeckholmiana afforded a new compound identified as kaempferol 3-O-beta-l-arabinopyranosyl-(1-->4)-alpha-l-rhamnopyranoside-7-O-alpha-l-rhamnopyranoside. Identification of the isolated compounds was based on chemical and spectroscopic analyses including UV, FABMS, (1)H, (13)C and 2D NMR, and DEPT. The cytotoxic activities of the compounds against several cancer cell lines were determined.
Ibrahim
Lamyaa F
LF
Phytochemistry and Plant Systematic Department, National Research Centre, Dokki 12622, Giza, Egypt.
Kawashty
Salwa A
SA
El-Hagrassy
Ali M
AM
Nassar
Mahmoud I
MI
Mabry
Tom J
TJ
D000970:Antineoplastic Agents / Q000302:isolation & purification* / Q000494:pharmacology; D045744:Cell Line, Tumor; D002470:Cell Survival / Q000187:drug effects; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D006801:Humans; D044949:Kaempferols; D000432:Methanol; D010936:Plant Extracts; D010946:Plants, Medicinal / Q000737:chemistry*; D014312:Trisaccharides
D000970:Antineoplastic Agents; D006027:Glycosides; D044949:Kaempferols; D010936:Plant Extracts; D014312:Trisaccharides; C006552:kaempferol; D000432:Methanol