Congenital hamartoma of the scalp with meningothelial, sebaceus, muscular, and immature glandular components.
A 4-month-old boy presented with a congenital, solitary, yellowish-red, eroded tumor on the scalp, histologically characterized by an ectopic proliferation of vascular and meningothelial elements intimately admixed with mature connective-tissue elements, adipose tissue, and smooth-muscular fibers. In addition, the presence of characteristic histopathological features of a nevus sebaceus and areas with immature glandular differentiation were observed. The diagnosis of a congenital hamartoma of the scalp with meningothelial, sebaceus, immature glandular, and muscular components was established. We review the heterogeneous group of cutaneous lesions with meningothelial elements and their pathogenesis.
Ferran
Marta
M
Department of Dermatology, Hospital del Mar-IMAS, Barcelona, Spain. mferran@imas.imim.es
Tribó
Maria J
MJ
González-Rivero
Miguel A
MA
Alameda
Francesc
F
Pujol
Ramon M
RM
D015415:Biomarkers / Q000378:metabolism; D002828:Choristoma / Q000151:congenital / Q000378:metabolism / Q000473:pathology*; D004847:Epithelial Cells / Q000473:pathology; D006222:Hamartoma / Q000151:congenital / Q000378:metabolism / Q000473:pathology*; D006801:Humans; D007223:Infant; D008297:Male; D008578:Meninges / Q000473:pathology*; D009130:Muscle, Smooth / Q000473:pathology*; D054000:Nevus, Sebaceous of Jadassohn / Q000473:pathology; D012535:Scalp / Q000473:pathology; D012627:Sebaceous Glands / Q000473:pathology*; D012871:Skin Diseases / Q000151:congenital / Q000378:metabolism / Q000473:pathology*
D015415:Biomarkers