Evidence for corticocortical connections between areas 7 and 17 in cerebral cortex of the cat.
This study provides the first evidence of direct corticocortical connections between areas 7 and 17 of the cat. Wheat germ agglutinin horseradish peroxidase (WGA-HRP) was administrated by micro-electrophoresis and micro-injection, respectively, into area 17 and area 7 in different hemispheres in eight cats. WGA-HRP labeled pyramidal neurons were observed primarily in layer 5 of areas 7 and 17 indicating that there are reciprocal connections between these areas. Optical imaging was used to guide WGA-HRP injections to single orientation columns in area 17. After such restricted injections labeled pyramidal cells were observed in layer 5 of area 7. These pyramidal cells were arranged as discontinuous patches extending across a broad region of area 7. These results suggest that feedback from area 7 to area 17 may arise from specific functional columns in area 7.
Han
Yanwen
Y
Vision Research Lab, Center for Brain Science Research, School of Life Sciences, Fudan University, Shanghai 200433, PR China.
Yang
Xu
X
Chen
Yuanxin
Y
Shou
Tiande
T
D000818:Animals; D002415:Cats; D002540:Cerebral Cortex / Q000166:cytology*; D014795:Visual Pathways / Q000166:cytology*