Selenoprotein S1: a novel inflammatory gene.
Selenoprotein S1 (SEPS1), a novel gene involved in the stress response of endoplasmic reticulum and inflammation control. Recent results provide a direct mechanistic link between SEPS1 and the production of inflammatory cytokines, suggesting SEPS1 may play a major role in the mediation of inflammation in IDDM and some other immunological disorders.
Wang
Jian-Min
JM
Department of Genetics, International Diabetes Institute, 250 Kooyang Road, Caulfield, VIC 3162, Australia. jianmin88@optusnet.com.au
D000818:Animals; D016207:Cytokines / Q000378:metabolism; D003920:Diabetes Mellitus / Q000473:pathology; D006801:Humans; D007249:Inflammation / Q000235:genetics*; D008565:Membrane Proteins / Q000235:genetics*; D051381:Rats; D051140:Selenoproteins / Q000235:genetics*
D016207:Cytokines; D008565:Membrane Proteins; C487710:SELENOS protein, human; D051140:Selenoproteins