4-Aminopyridine (fampridine) effectively treats amlodipine poisoning: a case report.
A case of a serious poisoning with the calcium entry blocker amlodipine is described, which was treated effectively with 4-aminopyridine. Calcium is suggested as general treatment of poisoning with calcium entry blockers in many guidelines. The use of intravenous 4-aminopyridine is theoretically useful to treat poisoning from calcium entry blockers and was demonstrated in this case report.
Wilffert
B
B
Department of Pharmacotherapy and Pharmaceutical Care, GUIDE, University of Groningen, Groningen, The Netherlands. b.wilffert@znb.nl
Boskma
R J
RJ
van der Voort
P H J
PH
Uges
D R A
DR
van Roon
E N
EN
Brouwers
J R B J
JR
D015761:4-Aminopyridine / Q000627:therapeutic use*; D017311:Amlodipine / Q000506:poisoning*; D002121:Calcium Channel Blockers / Q000506:poisoning*; D005260:Female; D006801:Humans; D008875:Middle Aged
D002121:Calcium Channel Blockers; D017311:Amlodipine; D015761:4-Aminopyridine