Sequence-specific cleavage of human telomere DNA by G-quadruplex formation.
In the current study, we reported that oligonucleotide with EDTA-Fe at 5' end causes a sequence specific break in human telomeric DNA strand by G-quadruplex formation.
Xu
Yan
Y
Research Center for Advanced Science and Technology, The University of Tokyo, 4-6-1 Komaba, Meguro-ku, Tokyo 153-8904, Japan.
Hirohata
Youhei
Y
Komiyama
Makoto
M
D001483:Base Sequence; D004492:Edetic Acid / Q000737:chemistry; D054856:G-Quadruplexes; D006801:Humans; D015345:Oligonucleotide Probes / Q000737:chemistry*; D016615:Telomere / Q000737:chemistry*
D015345:Oligonucleotide Probes; D004492:Edetic Acid