title: Congenital hamartoma of the scalp with meningothelial, sebaceus, muscular, and immature glandular components.
abstract: A 4-month-old boy presented with a congenital, solitary, yellowish-red, eroded tumor on the scalp, histologically characterized by an ectopic proliferation of vascular and meningothelial elements intimately admixed with mature connective-tissue elements, adipose tissue, and smooth-muscular fibers. In addition, the presence of characteristic histopathological features of a nevus sebaceus and areas with immature glandular differentiation were observed. The diagnosis of a congenital hamartoma of the scalp with meningothelial, sebaceus, immature glandular, and muscular components was established. We review the heterogeneous group of cutaneous lesions with meningothelial elements and their pathogenesis.
authors.affiliation: Department of Dermatology, Hospital del Mar-IMAS, Barcelona, Spain. mferran@imas.imim.es
authors.forename: Marta
authors.initials: M
authors.lastname: Ferran
authors.forename: Maria J
authors.initials: MJ
authors.lastname: Tribó
authors.forename: Miguel A
authors.initials: MA
authors.lastname: González-Rivero
authors.forename: Francesc
authors.initials: F
authors.lastname: Alameda
authors.forename: Ramon M
authors.initials: RM
authors.lastname: Pujol
mesh_terms: D015415:Biomarkers / Q000378:metabolism; D002828:Choristoma / Q000151:congenital / Q000378:metabolism / Q000473:pathology*; D004847:Epithelial Cells / Q000473:pathology; D006222:Hamartoma / Q000151:congenital / Q000378:metabolism / Q000473:pathology*; D006801:Humans; D007223:Infant; D008297:Male; D008578:Meninges / Q000473:pathology*; D009130:Muscle, Smooth / Q000473:pathology*; D054000:Nevus, Sebaceous of Jadassohn / Q000473:pathology; D012535:Scalp / Q000473:pathology; D012627:Sebaceous Glands / Q000473:pathology*; D012871:Skin Diseases / Q000151:congenital / Q000378:metabolism / Q000473:pathology*
chemical_list: D015415:Biomarkers