title: Spastic paraparesis, abnormal muscle biopsy and positive antithyroid antibodies.
abstract: A 35 year old lady presented with progressive spastic paraparesis and hyperintense signals in the spinal cord and brain. She was noted to have high titres of antithyroid antibodies and primary hypothyroidism. Her muscle biopsy showed perivascular lymphocytes around endomysial vessels. We highlight the association of spinal cord involvement and abnormal muscle biopsy in a case of Hashimotos encephalopathy.
authors.affiliation: Department of Neurology, Govt. Medical College, Calicut, Kerala.
authors.forename: A
authors.initials: A
authors.lastname: George
authors.forename: P
authors.initials: P
authors.lastname: Abdurahman
authors.forename: J
authors.initials: J
authors.lastname: James
mesh_terms: D000328:Adult; D001323:Autoantibodies / Q000276:immunology*; D001706:Biopsy; D018450:Disease Progression; D005260:Female; D050031:Hashimoto Disease / Q000175:diagnosis* / Q000276:immunology / Q000503:physiopathology; D006801:Humans; D007037:Hypothyroidism / Q000276:immunology; D020336:Paraparesis, Spastic; D013960:Thyroid Function Tests; D013961:Thyroid Gland / Q000276:immunology*
chemical_list: D001323:Autoantibodies