title: Acute renal failure due to acute tubular necrosis caused by direct invasion of Orientia tsutsugamushi.
abstract: We describe a scrub typhus patient with acute renal failure for whom a diagnosis was made based on serology as well as immunohistochemical (IHC) staining and an electron microscopic examination (EM) of a renal biopsy specimen. For our case, we demonstrated by IHC staining and EM that renal failure was caused by acute tubular necrosis due to a direct invasion of Orientia tsutsugamushi.
authors.affiliation: Department of Internal Medicine, Chosun University College of Medicine, 588 Seosuk-dong, Dong-gu, Gwangju 501-717, South Korea.
authors.forename: Dong-Min
authors.initials: DM
authors.lastname: Kim
authors.forename: Dae Woong
authors.initials: DW
authors.lastname: Kang
authors.forename: Jong O
authors.initials: JO
authors.lastname: Kim
authors.forename: Jong Hoon
authors.initials: JH
authors.lastname: Chung
authors.forename: Hyun Lee
authors.initials: HL
authors.lastname: Kim
authors.forename: Chi Young
authors.initials: CY
authors.lastname: Park
authors.forename: Sung-Chul
authors.initials: SC
authors.lastname: Lim
mesh_terms: D058186:Acute Kidney Injury / Q000209:etiology* / Q000382:microbiology / Q000473:pathology; D000328:Adult; D006801:Humans; D007150:Immunohistochemistry; D007683:Kidney Tubular Necrosis, Acute / Q000209:etiology / Q000382:microbiology* / Q000473:pathology; D008297:Male; D008854:Microscopy, Electron; D012285:Orientia tsutsugamushi / Q000302:isolation & purification / Q000472:pathogenicity*; D012612:Scrub Typhus / Q000150:complications* / Q000382:microbiology