title: Brain metastasis from non-seminomatous germ cell tumor of the testis.
abstract: Brain metastasis occurs rarely in patients with testicular cancer in the modern era where cisplatin-based chemotherapy regimens are used. The occurrence of brain metastasis can be synchronous or metachronous (with or without concurrent systemic disease). Long-term survival can be achieved in some patients. The vast majority of testicular cancer cases with brain metastasis reported in the literature involve nonseminomatous germ cell tumor and this subtype will be the focus of this review. This article reviews the literature of the diagnosis and management of brain metastasis from nonseminomatous germ cell tumor of the testis.
authors.affiliation: Indiana University Medical Center, Department of Radiation Oncology, 535 Barnhill Drive, RT041, Indianapolis, IN 46202, USA. jforquer@iupui.edu
authors.forename: Jeffrey A
authors.initials: JA
authors.lastname: Forquer
authors.forename: Matthew
authors.initials: M
authors.lastname: Harkenrider
authors.forename: Achilles J
authors.initials: AJ
authors.lastname: Fakiris
authors.forename: Robert D
authors.initials: RD
authors.lastname: Timmerman
authors.forename: Robert
authors.initials: R
authors.lastname: Cavaliere
authors.forename: Mark A
authors.initials: MA
authors.lastname: Henderson
authors.forename: Simon S
authors.initials: SS
authors.lastname: Lo
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use; D001932:Brain Neoplasms / Q000556:secondary* / Q000628:therapy; D002986:Clinical Trials as Topic; D003131:Combined Modality Therapy; D018237:Germinoma / Q000556:secondary* / Q000628:therapy; D006801:Humans; D008297:Male; D013736:Testicular Neoplasms / Q000473:pathology* / Q000628:therapy
chemical_list: D000970:Antineoplastic Agents