Eucalyptals A-C with a new skeleton isolated from Eucalyptus globulus.
Eucalyptals A-C (1-3) with a new skeleton of 3,5-diformyl-isopentyl phloroglucinol-coupled cadinane were isolated from the fruits of Eucalyptus globulus. Their structures were elucidated by spectroscopic analysis, and that of 1 was confirmed by single-crystal X-ray diffraction. The biosynthetic pathway of 1-3 was also postulated. Compounds 1-3 exhibited selective cytotoxicity against the HL-60 cell line.
Yin
Sheng
S
State Key Laboratory of Drug Research, Institute of Materia Medica, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 555 Zuchongzhi Road, Zhangjiang Hi-Tech Park, Shanghai 201203, PR China.
Xue
Jun-Juan
JJ
Fan
Cheng-Qi
CQ
Miao
Ze-Hong
ZH
Ding
Jian
J
Yue
Jian-Min
JM
D005052:Eucalyptus / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D008958:Models, Molecular; D010936:Plant Extracts / Q000737:chemistry*; D013729:Terpenes / Q000737:chemistry*
D010936:Plant Extracts; D013729:Terpenes