Synthesis of two repeat units corresponding to the backbone of the pectic polysaccharide rhamnogalacturonan I.
A tetrasaccharide corresponding to a sequence of the rhamnogalacturonan I backbone has been synthesized. This synthesis relies on only two protected monosaccharides and proceeds through a common disaccharide intermediate. Synthesis of this tetrasaccharide has been designed to allow for the addition of branching elements at the 4-positions of the rhamnosyl units, or further chain elongation at the 2-position.
Reiffarth
Dominic
D
Department of Chemistry, University of Northern British Columbia, 3333 University Way, Prince George, British Columbia, Canada V2N 4Z9.
Reimer
Kerry B
KB
D002240:Carbohydrate Sequence; D004187:Disaccharides / Q000737:chemistry; D009844:Oligosaccharides / Q000138:chemical synthesis*; D010368:Pectins / Q000737:chemistry*
D004187:Disaccharides; D009844:Oligosaccharides; C042491:rhamnogalacturonan I; D010368:Pectins