Conjunctival pigmentation in Stevens-Johnson syndrome.
We report a 29-year-old white female with conjunctival pigmentation after a Stevens-Johnson syndrome (SJS) episode triggered by sulfasalazine. The patient developed bilateral tarsal and forniceal conjunctiva and black pigmentation. Diagnostic biopsy showed stromal monocyte infiltration consistent with chronic phase SJS and conjunctival pigment of melanic origin and not due to drug deposition. Treatment with topical steroids and unpreserved artificial tears resulted in improvement of clinical symptoms; however, pigmentation was unchanged after 2 years.
Fuentes-Páez
Graciana
G
IOBA (Institute of Ophthalmobiology), University of Valladolid, Ramón y Cajal 7, Valladolid, 47005, Spain.
Mendez
Maria C
MC
Montañez
Javier
J
Herreras
Jose M
JM
Saornil
Maria A
MA
Calonge
Margarita
M
D000328:Adult; D003229:Conjunctival Diseases / Q000150:complications* / Q000628:therapy; D004848:Epithelium / Q000473:pathology; D005260:Female; D006760:Hospitalization; D006801:Humans; D010859:Pigmentation Disorders / Q000150:complications* / Q000628:therapy; D013262:Stevens-Johnson Syndrome / Q000150:complications* / Q000628:therapy