title: A patient with Takayasu's arteritis and rheumatoid arthritis who responded to tacrolimus hydrate.
abstract: We encountered the rare case of a 50-year-old woman who developed rheumatoid arthritis (RA) while suffering from Takayasu's arteritis of arch vessel type. prednisolone (PSL) therapy was continued at a maintenance dose of 7.5 mg due to recurring inflammation. She was affected with RA for 7 years after Takayasu's arteritis. Disease-modifying antirheumatic drugs (DMARDs) were unusable because of side effects. In the summer of 2005, RA activity increased, and treatment with tacrolimus hydrate at 1.5 mg was started; thereafter, the activity of RA and Takayasu's arteritis was relieved, especially MRA findings. We report that therapy with tacrolimus hydrate markedly relieved two disorders, and review the literature.
authors.affiliation: Department of Internal Medicine, Itabashi Medical Center Hospital, Tokyo. loz-i.y@hotmail.co.jp
authors.forename: Isamu
authors.initials: I
authors.lastname: Yokoe
authors.forename: Hitomi
authors.initials: H
authors.lastname: Haraoka
authors.forename: Hideaki
authors.initials: H
authors.lastname: Harashima
mesh_terms: D000792:Angiography; D001172:Arthritis, Rheumatoid / Q000150:complications / Q000000981:diagnostic imaging / Q000188:drug therapy*; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D008875:Middle Aged; D016559:Tacrolimus / Q000627:therapeutic use*; D013625:Takayasu Arteritis / Q000150:complications / Q000000981:diagnostic imaging / Q000188:drug therapy*
chemical_list: D007166:Immunosuppressive Agents; D016559:Tacrolimus