title: [Late-onset hemorrhagic infarction in patients with patent foramen ovale: reports of two cases].
abstract: We presented here two patients with hemorrhagic infarction occurred during subacute phase of brain embolism. The patients were 71-year-old and 73-year-old men who suffered from brain infarction of the left posterior cerebral artery and right middle cerebral artery territory, respectively. Both of them were diagnosed as having cryptogenic stroke and patent foramen ovale. After transferred to rehabilitation hospitals taking aspirin for a secondary prevention of stroke, they developed hemorrhagic infarction at day 17 and day 19, respectively. Their blood pressure remained within normal range throughout acute and subacute phase. Although most of hemorrhagic infarction occurs within 24 hours of stroke onset, some patients develop symptomatic hemorrhagic infarction even after 10 days. We need to be careful about late-onset hemorrhagic infarction, because many patients are now transferred early to rehabilitation hospitals to facilitate dedicated systematic rehabilitation.
authors.affiliation: Department of Neurology, Kumamoto City Hospital.
authors.forename: Yasuyuki
authors.initials: Y
authors.lastname: Ito
authors.forename: Akira
authors.initials: A
authors.lastname: Mori
authors.forename: Kiminobu
authors.initials: K
authors.lastname: Yonemura
authors.forename: Yoichiro
authors.initials: Y
authors.lastname: Hashimoto
authors.forename: Teruyuki
authors.initials: T
authors.lastname: Hirano
authors.forename: Makoto
authors.initials: M
authors.lastname: Uchino
mesh_terms: D000210:Acute-Phase Reaction; D000368:Aged; D001241:Aspirin / Q000008:administration & dosage; D002543:Cerebral Hemorrhage / Q000209:etiology* / Q000534:rehabilitation*; D002544:Cerebral Infarction / Q000209:etiology* / Q000534:rehabilitation*; D054092:Foramen Ovale, Patent / Q000150:complications*; D006801:Humans; D020766:Intracranial Embolism / Q000150:complications*; D008297:Male; D020521:Stroke / Q000150:complications* / Q000517:prevention & control; D013997:Time Factors
chemical_list: D001241:Aspirin