The effects of different doses of remifentanil on intraocular pressure after tracheal intubation: a randomized, double-blind and prospective study.
We investigated the effects of alfentanil and different doses of remifentanil on intraocular pressure (IOP) and hemodynamic responses during laryngoscopy and endotracheal intubation in 60 patients. IOP values decreased significantly from 30 seconds before the intubation to 5 minutes after intubation measurements compared to baseline values in all the groups. However, a significant increase in IOP was recorded in the 0.5-microg remifentanil group after tracheal intubation.
Kaygusuz
Kenan
K
Department of Anesthesiology, Cumhuriyet University School of Medicine, Sivas, 58140, Turkey. kaygusuzkenan@gmail.com
Toker
M Ilker
MI
Kol
Iclal Ozdemir
IO
Erdogan
Haydar
H
Gursoy
Sinan
S
Mimaroglu
Caner
C
D000328:Adult; D015760:Alfentanil / Q000627:therapeutic use; D000701:Analgesics, Opioid / Q000008:administration & dosage* / Q000627:therapeutic use; D004305:Dose-Response Relationship, Drug; D004311:Double-Blind Method; D005260:Female; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D007429:Intraocular Pressure / Q000187:drug effects*; D007442:Intubation, Intratracheal / Q000009:adverse effects*; D007828:Laryngoscopy / Q000009:adverse effects*; D008297:Male; D010880:Piperidines / Q000008:administration & dosage* / Q000627:therapeutic use; D017450:Receptors, Opioid, mu / Q000819:agonists; D000077208:Remifentanil; D013997:Time Factors
D000701:Analgesics, Opioid; D010880:Piperidines; D017450:Receptors, Opioid, mu; D015760:Alfentanil; D000077208:Remifentanil