title: Isolated orbital endodermal sinus tumor.
abstract: OBJECTIVE
  To describe the clinical, serologic, histopathologic, and immunohistochemical findings of an isolated endodermal sinus tumor of the orbit in a 1-year-old boy.
  
  
  METHODS
  A retrospective case report and literature review.
  
  
  RESULTS
  The patient was managed by the ophthalmology and oncology services. After the diagnosis was established by serologic analysis and histopathology, the patient underwent chemotherapy.
  
  
  CONCLUSIONS
  Endodermal sinus tumor is a malignant germ-cell tumor that usually involves the gonadal tissue. Primary extragonadal sites occur rarely, and include the orbit. Treatment options include surgical removal and chemotherapy.
authors.affiliation: Department of Ophthalmology (Khatam-Al-Anbia Eye Hospital), Mashhad University of Medical Sciences, Iran. saberaa@mums.ac.ir
authors.forename: Aliakbar Saber
authors.initials: AS
authors.lastname: Mogaddam
authors.forename: Bahram
authors.initials: B
authors.lastname: Memar
authors.forename: Amir
authors.initials: A
authors.lastname: Aledavood
authors.forename: Alireza
authors.initials: A
authors.lastname: Eslampoor
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D014408:Biomarkers, Tumor / Q000032:analysis; D003131:Combined Modality Therapy; D018240:Endodermal Sinus Tumor / Q000000981:diagnostic imaging / Q000473:pathology* / Q000628:therapy; D006801:Humans; D007223:Infant; D008297:Male; D009918:Orbital Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000628:therapy; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed; D000509:alpha-Fetoproteins / Q000032:analysis
chemical_list: C097353:AFP protein, human; D014408:Biomarkers, Tumor; D000509:alpha-Fetoproteins