Synthesis of quinoline-2-thiones via tandem indium(III)-promoted Friedel-Crafts alkenylation-cyclization of 2-alkynylphenyl isothiocyanates.
A new approach to the synthesis of 4-aryl- or 4-arylthioquinoline-2-thiones via indium(III) reagent-mediated tandem Friedel-Crafts alkenylation-cyclization of 2-alkynylphenyl isothiocyanates is described.
Otani
Takashi
T
Department of Chemistry, Faculty of Science, Tokyo University of Science, Kagurazaka, Shinjuku-ku, Tokyo 162-8601, Japan. totani@rs.kagu.tus.ac.jp
Kunimatsu
Shinichi
S
Nihei
Hiroshi
H
Abe
Yuko
Y
Saito
Takao
T
D000475:Alkenes / Q000737:chemistry*; D003500:Cyclization; D007204:Indium / Q000737:chemistry*; D017879:Isothiocyanates / Q000737:chemistry*; D011804:Quinolines / Q000737:chemistry*
D000475:Alkenes; D017879:Isothiocyanates; D011804:Quinolines; D007204:Indium