title: [Deciding on analgesic prescription dosing for acute back pain: once daily or more?].
abstract: BACKGROUND
  Decisions about treatment prescriptions depend on many factors. For example, the choice of once-daily or multiple administration of an analgesic, an aspect that is not determined by guidelines, depends essentially on medical practice habits, patient preferences, or both. We analyzed this treatment decision for acute back pain in a case-control study.
  
  
  METHODS
  A case-control study was conducted in metropolitan France between October and December 2005 among outpatients seeing general practitioners and specialists for acute back pain (cervical, thoracic, lumbar and low back pain). We compared the group treated by a once-daily analgesic (tramadol) with those treated by analgesics (WHO analgesic ladder steps 1 and 2) administered twice daily or more. Patients and physicians were questioned about the different supposed determinants of the treatment choice for acute back pain.
  
  
  RESULTS
  Patients for whom physicians prescribed a once-daily analgesic had a history of back pain and previous prescriptions for other analgesics more frequently than the other patients, experienced significantly greater pain and more marked disability. The time to recovery estimated by the physicians was shorter for these patients, as was the time to return to work, estimated by patients. Treatment choice was also guided by the patient's choices: the once-daily analgesic was reserved for patients who prefer to take drugs to prevent pain and prefer a single dose daily.
  
  
  CONCLUSIONS
  The choice of type of analgesic treatment for acute back pain depends not only on clinical condition (pain and disability), but also on clinical history, the future as envisioned by the physician and the patient's desires. Action to improve treatment choices must integrate these factors, especially as part of an overall education in therapeutics.
authors.affiliation: Service de médecine interne et consultation de la douleur, AP-HP, Hôtel-Dieu, Université Paris V Descartes, F-75004 Paris, France. Serge.perrot@htd.aphp.fr
authors.forename: Serge
authors.initials: S
authors.lastname: Perrot
authors.forename: Victor
authors.initials: V
authors.lastname: Concas
authors.forename: Francis
authors.initials: F
authors.lastname: Allaert
authors.forename: Françoise
authors.initials: F
authors.lastname: Laroche
mesh_terms: D000208:Acute Disease; D000700:Analgesics / Q000627:therapeutic use*; D001416:Back Pain / Q000188:drug therapy*; D016022:Case-Control Studies; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged
chemical_list: D000700:Analgesics