title: Formation of the imidazolinone ring under mild conditions in the presence of sodium hydride.
abstract: Substituted imidazolinones containing heterocyclic carboxylic acids as substituents and possessing herbicidal properties were synthesized by cyclization of 2-amino-2,3-dimethylbutyramide with heterocyclic ethyl dicarboxylates under mild conditions. The use of NaH as base leads to a significant increase in the reaction rate and allows the preparation of the target compounds in high yields.
authors.affiliation: Center for Chemical Research and Technologies, Cordoba Faculty, National Technological University, C.C. 17, Suc. 16, Cordoba 5016, Argentina. vasiliev@scdt.frc.utn.edu.ar
authors.forename: Aleksey N
authors.initials: AN
authors.lastname: Vasiliev
authors.forename: Antonio F
authors.initials: AF
authors.lastname: Lopez
authors.forename: Julio D
authors.initials: JD
authors.lastname: Fernandez
authors.forename: Anibal J
authors.initials: AJ
authors.lastname: Mocchi
mesh_terms: D007093:Imidazoles / Q000138:chemical synthesis* / Q000737:chemistry; D017670:Sodium Compounds / Q000737:chemistry*
chemical_list: D007093:Imidazoles; D017670:Sodium Compounds; C524957:sodium hydride