Automatic analysis of microRNA microarray images using mathematical morphology.
The micro array are an experimental technique for parallel determination of molecular concentration. The image analysis is an important, time consuming and error prone step of the process. We describe here an automatic procedure able to analyze the micro array data and to accurately provide the level of concentration for each microRNA (miRNA). The proposed method has the advantage, compared to commercial products, to minimize the user interaction, leading to a more reproducible data analysis.
Meyenhofer
Felix
F
University of Applied Sciences, Geneva.
Schaad
Olivier
O
Descombes
Patrick
P
Kocher
Michel
M
D000465:Algorithms; D001185:Artificial Intelligence; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D035683:MicroRNAs / Q000032:analysis* / Q000235:genetics*; D046228:Microarray Analysis / Q000379:methods*; D008856:Microscopy, Fluorescence / Q000379:methods*; D010363:Pattern Recognition, Automated / Q000379:methods*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity
D035683:MicroRNAs