title: Dedicated cone-beam breast CT: feasibility study with surgical mastectomy specimens.
abstract: OBJECTIVE
  The purpose of this study was to investigate the feasibility of diagnostic breast imaging using a flat-panel detector-based cone-beam CT system.
  
  
  CONCLUSIONS
  Imaging of 12 mastectomy specimens was performed at 50-80 kVp with a voxel size of 145 or 290 microm. Our study shows that cone-beam breast CT images have exceptional tissue contrast and can potentially reduce examination time with comparable radiation dose.
authors.affiliation: Department of Diagnostic Radiology, The University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Blvd., Unit 1350, Houston, TX 77030, USA. wyang@di.mdacc.tmc.edu
authors.forename: Wei Tse
authors.initials: WT
authors.lastname: Yang
authors.forename: Selin
authors.initials: S
authors.lastname: Carkaci
authors.forename: Lingyun
authors.initials: L
authors.lastname: Chen
authors.forename: Chao-Jen
authors.initials: CJ
authors.lastname: Lai
authors.forename: Aysegul
authors.initials: A
authors.lastname: Sahin
authors.forename: Gary J
authors.initials: GJ
authors.lastname: Whitman
authors.forename: Chris C
authors.initials: CC
authors.lastname: Shaw
mesh_terms: D000328:Adult; D000368:Aged; D001943:Breast Neoplasms / Q000000981:diagnostic imaging*; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D021621:Imaging, Three-Dimensional / Q000379:methods*; D008408:Mastectomy; D008875:Middle Aged; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D036542:Tomography, Spiral Computed / Q000379:methods*; D014057:Tomography, X-Ray Computed / Q000379:methods*