title: JASPAR, the open access database of transcription factor-binding profiles: new content and tools in the 2008 update.
abstract: JASPAR is a popular open-access database for matrix models describing DNA-binding preferences for transcription factors and other DNA patterns. With its third major release, JASPAR has been expanded and equipped with additional functions aimed at both casual and power users. The heart of the JASPAR database-the JASPAR CORE sub-database-has increased by 12% in size, and three new specialized sub-databases have been added. New functions include clustering of matrix models by similarity, generation of random matrices by sampling from selected sets of existing models and a language-independent Web Service applications programming interface for matrix retrieval. JASPAR is available at http://jaspar.genereg.net.
authors.affiliation: Computational Biology Unit, Bergen Center for Computational Science, University of Bergen, Thormøhlensgate 55, N-5008 Bergen, Norway.
authors.forename: Jan Christian
authors.initials: JC
authors.lastname: Bryne
authors.forename: Eivind
authors.initials: E
authors.lastname: Valen
authors.forename: Man-Hung Eric
authors.initials: MH
authors.lastname: Tang
authors.forename: Troels
authors.initials: T
authors.lastname: Marstrand
authors.forename: Ole
authors.initials: O
authors.lastname: Winther
authors.forename: Isabelle
authors.initials: I
authors.lastname: da Piedade
authors.forename: Anders
authors.initials: A
authors.lastname: Krogh
authors.forename: Boris
authors.initials: B
authors.lastname: Lenhard
authors.forename: Albin
authors.initials: A
authors.lastname: Sandelin
mesh_terms: D022126:Access to Information; D000818:Animals; D001665:Binding Sites; D019295:Computational Biology; D003627:Data Interpretation, Statistical; D030561:Databases, Nucleic Acid; D006801:Humans; D020407:Internet; D008957:Models, Genetic; D011401:Promoter Regions, Genetic; D022821:RNA Splice Sites; D050436:Regulatory Elements, Transcriptional; D012984:Software; D014157:Transcription Factors / Q000378:metabolism*; D014584:User-Computer Interface
chemical_list: D022821:RNA Splice Sites; D014157:Transcription Factors