title: Twelve years survival with repeated hepatectomy and lung resection for metastasis from carcinoma of the papilla of Vater after pancreaticoduodenectomy.
abstract: We present a 60-year-old woman who underwent three times hepatectomy and lung resection for metastasis originating from a carcinoma of the papilla of Vater after pancreaticoduodenectomy with lymphadenectomy during 12 years. Pancreaticoduodenectomy was performed in 1980 and histological examination of original tumor revealed a stage IIA papillary adenocarcinoma (pT3, pN0, pM0). Repetitive hepatectomy underwent in 1986 (S7,8), 1988 (S2), 1991 (S4) and bilateral partial resection of lung (right S1, left S2.3) in 1990. She died from multiple skin, bone and lung metastases 12 years after pancreaticoduodenectomy. The current case is very rare, however, if patients with carcinoma of the papilla of Vater have localized liver metastases and no local recurrence, liver metastases should be resected to improve the chances for long-term survival.
authors.affiliation: Gastroenterology and General Surgery, Yamagata University School of Medicine, Yamagata, Japan. tmoriya@med.id.yamagata-u.ac.jp
authors.forename: Toshiyuki
authors.initials: T
authors.lastname: Moriya
authors.forename: Wataru
authors.initials: W
authors.lastname: Kimura
authors.forename: Ichiro
authors.initials: I
authors.lastname: Hirai
authors.forename: Masaomi
authors.initials: M
authors.lastname: Mizutani
authors.forename: Takashi
authors.initials: T
authors.lastname: Yamamoto
authors.forename: Ryo
authors.initials: R
authors.lastname: Toya
authors.forename: Masahiro
authors.initials: M
authors.lastname: Kamiga
authors.forename: Akira
authors.initials: A
authors.lastname: Fuse
mesh_terms: D000231:Adenocarcinoma, Papillary / Q000601:surgery; D014670:Ampulla of Vater / Q000473:pathology / Q000601:surgery*; D002277:Carcinoma / Q000601:surgery* / Q000628:therapy*; D003138:Common Bile Duct Neoplasms / Q000601:surgery* / Q000628:therapy*; D005260:Female; D006498:Hepatectomy / Q000379:methods*; D006801:Humans; D008168:Lung / Q000601:surgery*; D008175:Lung Neoplasms / Q000556:secondary* / Q000601:surgery; D008875:Middle Aged; D009362:Neoplasm Metastasis; D016577:Pancreaticoduodenectomy / Q000379:methods*; D013997:Time Factors; D016896:Treatment Outcome