Effect of n-tyrosol on blood viscosity and platelet aggregation.
Experiments on rats showed that n-tyrosol limited the increase in blood viscosity during thermal exposure at a shear rate of 5-300 sec(-1) and inhibited ADP-induced platelet aggregation. The effects of n-tyrosol are comparable to that of pentoxyphylline.
Plotnikov
M B
MB
Institute of Pharmacology, Tomsk Research Center, Siberian Division of Russian Academy of Medical Sciences, Novosibirsk.
Chernysheva
G A
GA
Smol'yakova
V I
VI
Maslov
M Yu
MY
Cherkashina
I V
IV
Krysin
A P
AP
Sorokina
I V
IV
Tolstikova
T G
TG
D000818:Animals; D001809:Blood Viscosity / Q000187:drug effects*; D018056:Hemorheology; D066298:In Vitro Techniques; D008297:Male; D010626:Phenylethyl Alcohol / Q000031:analogs & derivatives* / Q000494:pharmacology; D010974:Platelet Aggregation / Q000187:drug effects*; D010975:Platelet Aggregation Inhibitors / Q000494:pharmacology*; D051381:Rats; D017208:Rats, Wistar
D010975:Platelet Aggregation Inhibitors; C011867:4-hydroxyphenylethanol; D010626:Phenylethyl Alcohol