title: Testicular sperm extraction in a single cancerous testicle in patients with azoospermia: a case report.
abstract: OBJECTIVE
  To optimize the management of patients with cancer in a single testis and azoospermia.
  
  
  METHODS
  Case report.
  
  
  METHODS
  Reproductive biology department.
  
  
  METHODS
  Two male patients referred in an emergency context for gamete cryopreservation before castration for cancer in a single testis; the patients were azoospermic before any sterilizing treatment.
  
  
  METHODS
  Testicular sperm extraction (TESE) was carried out synchronously with orchiectomy, allowing the cryopreservation of testicular spermatozoa.
  
  
  METHODS
  One year after the end of the cancer treatment, thawed testicular spermatozoa were successfully used in an intracytoplasmic sperm injection procedure. A twin pregnancy was obtained, and a healthy boy and girl were born.
  
  
  CONCLUSIONS
  TESE and cryopreservation could be offered to every patient with cancer in a single testis and azoospermia.
authors.affiliation: Department of Gynécologie-Obstétrique, Hôpital Nord, Saint Etienne, France.
authors.forename: Laure
authors.initials: L
authors.lastname: Descombe
authors.forename: Céline
authors.initials: C
authors.lastname: Chauleur
authors.forename: Anne
authors.initials: A
authors.lastname: Gentil-Perret
authors.forename: Isabelle
authors.initials: I
authors.lastname: Aknin-Seifer
authors.forename: Jacques
authors.initials: J
authors.lastname: Tostain
authors.forename: Rachel
authors.initials: R
authors.lastname: Lévy
mesh_terms: D053713:Azoospermia / Q000150:complications*; D015925:Cryopreservation; D005260:Female; D006801:Humans; D008297:Male; D009919:Orchiectomy; D011247:Pregnancy; D012662:Semen Preservation; D020554:Sperm Injections, Intracytoplasmic; D013736:Testicular Neoplasms / Q000150:complications / Q000601:surgery*; D013737:Testis / Q000601:surgery; D020858:Tissue and Organ Harvesting