title: Social mobilisation, drug coverage and compliance and adverse reactions in a Mass Drug Administration (MDA) Programme for the Elimination of Lymphatic Filariasis in Sri Lanka.
abstract: BACKGROUND
  In Sri Lanka filariasis is endemic in Southern, Western and North Western provinces covering eight districts designated as implementation units in the Programme for the Elimination of Lymphatic Filariasis (PELF). Despite control activities over sixty years including multidose diethylcarbamazine, 6 mg/kg treatment microfilaria rates had persisted at low levels. Following systematic social mobilisation the first MDA with DEC albendazole combination was conducted in 2002.
  
  
  METHODS
  We investigated the extent social mobilisation had reached the people, their drug compliance and adverse reactions. Three localities were selected from each district to pick target population samples for pre-tested questionnaire. Three teams each with six people visited one district each day. One team worked from three starting points in one locality. A member applied eight part questionnaire to one family member totalling 150-160 people from one locality. Questions included social mobilisation, drug compliance and adverse reactions.
  
  
  RESULTS
  Information was disseminated by television, radio, banners and leaflets, to a lesser extent by people. Information reached more people in the periphery than in Colombo. 35.2% from Colombo municipality were unaware of the MDA. Drug coverage was 79.6%, home delivery 71.7% and delivery centres 7.9%. 35.6% in Colombo district and 53.4% from Colombo municipality did not receive drugs. Drugs were consumed by 71.4%. 28.6% who did not comply included 20.4% who did not receive them. 91.4% showed no adverse reactions, 7.5% were mild, 1.1% recovered with home remedies.
  
  
  CONCLUSIONS
  Drug compliance showed significant positive correlation with awareness of the MDA. Door to door delivery was more successful than delivery from centres. More delivery centres conveniently located would have rectified this disparity. Poor awareness and compliance in Colombo and urban areas could be rectified with separate strategy for urban areas. More time for MDA and trained adequate manpower would ensure coverage to achieve elimination.
authors.affiliation: Filariasis Research Training and Service Unit, Faculty of Medicine, University of Ruhuna, Sri Lanka. miraniweera@yahoo.co.uk
authors.forename: Mirani V
authors.initials: MV
authors.lastname: Weerasooriya
authors.forename: Channa T
authors.initials: CT
authors.lastname: Yahathugoda
authors.forename: Darshana
authors.initials: D
authors.lastname: Wickramasinghe
authors.forename: Kithsiri N
authors.initials: KN
authors.lastname: Gunawardena
authors.forename: Rohan A
authors.initials: RA
authors.lastname: Dharmadasa
authors.forename: Kanchana K
authors.initials: KK
authors.lastname: Vidanapathirana
authors.forename: Saman H
authors.initials: SH
authors.lastname: Weerasekara
authors.forename: Wilfred A
authors.initials: WA
authors.lastname: Samarawickrema