1-Hydroxymethyl-4-phenylsulfonybutadiene, a versatile building block for the synthesis of 2,3,4-trisusbtituted tetrahydrothiophenes.
A method to synthesize chiral 2,3,4-trisusbtituted tetrahydrothiophenes in both enantiomerically pure forms starting from 1-hydroxymethyl-4-phenylsulfonylbutadiene is described.
Díez
David
D
Dpto. de Química Orgánica, Universidad de Salamanca, Plaza de los Caídos 1-5, 37008 Salamanca, Spain. ddm@usal.es
Benéitez
M Templo
MT
Marcos
Isidro S
IS
Garrido
N M
NM
Basabe
P
P
Urones
Julio G
JG
D002070:Butadienes / Q000737:chemistry*; D008956:Models, Chemical; D015394:Molecular Structure; D013237:Stereoisomerism; D013450:Sulfones / Q000737:chemistry*; D013876:Thiophenes / Q000138:chemical synthesis* / Q000737:chemistry
C524853:1-hydroxymethyl-4-phenylsulfonylbutadiene; D002070:Butadienes; D013450:Sulfones; D013876:Thiophenes; C121030:tetrahydrothiophene