Cerebral venous thrombosis in newborns, infants and children.
Cerebral venous thrombosis is currently thought to be a relatively rare and benign entity in childhood. Recent studies however have shown that cerebral venous thrombosis is more common than previously believed, and carries significant mortality and neurologic morbidity. Neonates are the most commonly affected age group, compared to children >1 month of age. Magnetic resonance imaging venography is the gold standard by which this diagnosis should be made. Clinical trials are currently necessary to determine the most efficacious,safe, and age-specific approach for anticoagulation for this childhood disorder.
Yager
Jerome Y
JY
Department of Pediatrics, Stollery Children's Hospital, University of Alberta, Edmonton, Alberta, Canada. jyager@ualberta.ca
Black
Karina
K
Bauman
Mary
M
Massicotte
Patricia
P
D002550:Cerebral Veins / Q000473:pathology*; D002675:Child, Preschool; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D020767:Intracranial Thrombosis / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy; D010372:Pediatrics