title: Temporal trend in and spatial distribution of lung cancer mortality in Brazil between 1979 and 2004: magnitude, regional patterns, and gender-related differences.
abstract: OBJECTIVE
  To describe the temporal trend in and spatial distribution of mortality from tracheal, bronchial, and lung cancer in Brazil from 1979 to 2004.
  
  
  METHODS
  Mortality data by gender and geographic region were obtained from the Mortality Database created by the Ministry of Health in 1975. Demographic data were collected from the national censuses, from population counts, and from population estimates made in non-census years. Mortality rates were standardized according to the direct method, and the trends were analyzed by gender and geographic region using the Prais-Winsten method for generalized linear regression.
  
  
  RESULTS
  Lung cancer mortality accounted for approximately 12% of the overall neoplasia-related mortality during the period. There was a trend toward an increase for both genders and in all regions, except for the male population in the southeast region, whose rates remained steady between 1979 and 2004. The highest rates were observed in the south and southeast regions. However, the northeast region was the one that presented the greatest increase, followed by the central-west and north regions. In all regions, the increase in mortality rates was higher in women.
  
  
  CONCLUSIONS
  The increase in lung cancer mortality in Brazil between 1979 and 2004 requires public measures that can minimize exposition to risk factors, mainly tobacco, and allow greater access to health care facilities for diagnosis and treatment.
authors.affiliation: Federal University of Santa Catarina, Florianópolis (SC) Brazil. boing@ccs.ufsc.br
authors.forename: Antonio Fernando
authors.initials: AF
authors.lastname: Boing
authors.forename: Tiana Fávero
authors.initials: TF
authors.lastname: Rossi
mesh_terms: D001938:Brazil / Q000453:epidemiology; D001984:Bronchial Neoplasms / Q000401:mortality*; D019352:Censuses; D016000:Cluster Analysis; D005260:Female; D006801:Humans; D016014:Linear Models; D008175:Lung Neoplasms / Q000401:mortality*; D008297:Male; D017678:Sex Distribution; D013997:Time Factors; D014134:Tracheal Neoplasms / Q000401:mortality*