title: Structural biology in plant natural product biosynthesis--architecture of enzymes from monoterpenoid indole and tropane alkaloid biosynthesis.
abstract: Several cDNAs of enzymes catalyzing biosynthetic pathways of plant-derived alkaloids have recently been heterologously expressed, and the production of appropriate enzymes from ajmaline and tropane alkaloid biosynthesis in bacteria allows their crystallization. This review describes the architecture of these enzymes with and without their ligands.
authors.affiliation: College of Pharmaceutical Sciences, Zijingang Campus, Zhejiang University, 310058, Hangzhou, China.
authors.forename: Joachim
authors.initials: J
authors.lastname: Stöckigt
authors.forename: Santosh
authors.initials: S
authors.lastname: Panjikar
mesh_terms: D001688:Biological Products / Q000096:biosynthesis / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D026121:Indole Alkaloids / Q000138:chemical synthesis / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D015394:Molecular Structure; D010946:Plants, Medicinal / Q000737:chemistry* / Q000201:enzymology
chemical_list: D001688:Biological Products; D026121:Indole Alkaloids