title: No relation between angiotensin-converting enzyme gene polymorphism and pseudoexfoliation.
abstract: OBJECTIVE
  To determine the association between the angiotensin-converting enzyme insertion/deletion (I/D) polymorphism and pseudoexfoliation (PEX) in Turkish patients.
  
  
  METHODS
  This prospective study consisted of 89 patients with PEX, and 120 controls. The I/D polymorphism of the angiotensin-converting enzyme gene was measured with the use of the polymerase chain reaction method.
  
  
  RESULTS
  The distribution of the polymorphism was not significantly different in cases with PEX and controls. The frequencies of the I and D alleles were not significantly different between the groups.
  
  
  CONCLUSIONS
  According to our findings, I/D polymorphism in the angiotensin-converting enzyme gene does not play any role in the pathogenesis of PEX.
authors.affiliation: Department of Ophthalmology, Faculty of Medicine, Ankara University, Ankara, Turkey. oyatekeli@tr.net
authors.forename: Oya
authors.initials: O
authors.lastname: Tekeli
authors.forename: M Erol
authors.initials: ME
authors.lastname: Turaçli
authors.forename: Buket
authors.initials: B
authors.lastname: Altinok
authors.forename: Nejat
authors.initials: N
authors.lastname: Akar
authors.forename: Atilla Halil
authors.initials: AH
authors.lastname: Elhan
mesh_terms: D000368:Aged; D004251:DNA Transposable Elements; D017889:Exfoliation Syndrome / Q000235:genetics*; D005260:Female; D017353:Gene Deletion; D005787:Gene Frequency; D006801:Humans; D008297:Male; D008875:Middle Aged; D007703:Peptidyl-Dipeptidase A / Q000235:genetics*; D016133:Polymerase Chain Reaction; D011110:Polymorphism, Genetic
chemical_list: D004251:DNA Transposable Elements; D007703:Peptidyl-Dipeptidase A