Mammalian sperm chromatin structure and assessment of DNA fragmentation.
This review article illustrates the biology of mammalian sperm chromatin structure. The possible causes of DNA (deoxyribonucleic acid) fragmentation are discussed. Also available molecular techniques for assessment of mammalian sperm DNA damage are described.
Andrabi
S M H
SM
Animal Reproduction Laboratory, Animal Sciences Institute, National Agricultural Research Centre, Park Road, Islamabad, 45500, Pakistan. andrabi123@yahoo.com
D000818:Animals; D017209:Apoptosis / Q000235:genetics / Q000502:physiology; D002843:Chromatin / Q000737:chemistry*; D004249:DNA Damage; D053938:DNA Fragmentation; D042003:DNA Packaging / Q000502:physiology; D005821:Genetic Techniques; D006657:Histones / Q000378:metabolism / Q000502:physiology; D006801:Humans; D008297:Male; D009687:Nuclear Proteins / Q000378:metabolism / Q000502:physiology; D018384:Oxidative Stress / Q000235:genetics / Q000502:physiology; D011479:Protamines / Q000378:metabolism; D013094:Spermatozoa / Q000378:metabolism* / Q000648:ultrastructure
D002843:Chromatin; D006657:Histones; D009687:Nuclear Proteins; D011479:Protamines