title: Thymalfasin: clinical pharmacology and antiviral applications.
abstract: Thymalfasin (thymosin-alpha1) is an immunomodulatory agent that is able to augment some specific T lymphocyte functions, particularly that of promoting the T helper 1 cell responses involved in host antiviral defence. The most promising clinical applications for thymalfasin seem to be as a single agent for the treatment of chronic hepatitis B and in combination with interferon-alpha for the treatment of both chronic hepatitis B and C. These positive preliminary results offer a strong rationale for larger, well-planned clinical trials and also for defining the optimal schedule of administration.
authors.affiliation: Dipartimento di Medicina Interna, Cardioangiologia ed Epatologia, University of Bologna, Bologna, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Gramenzi
authors.forename: C
authors.initials: C
authors.lastname: Cursaro
authors.forename: P
authors.initials: P
authors.lastname: Andreone
authors.forename: M
authors.initials: M
authors.lastname: Bernardi