Versatility of borane nucleic acids mimics for coding, decoding and modulating genetic information.
This presentation will focus on the targeted regulation of gene expression, effective siRNA silencing with boranophosphates, and suppression of drugresistant reverse transcriptase by boranophosphate nucleotide analogues.
Shaw
Barbara Ramsay
BR
Department of Chemistry, Box 90354, Duke University, Durham, NC 27708, USA. barbara.r.shaw@duke.edu
D001880:Boranes / Q000737:chemistry*; D009841:Oligonucleotides / Q000737:chemistry*; D010710:Phosphates / Q000737:chemistry*; D034622:RNA Interference; D018894:Reverse Transcriptase Inhibitors / Q000737:chemistry
D001880:Boranes; D009841:Oligonucleotides; D010710:Phosphates; D018894:Reverse Transcriptase Inhibitors; C510710:boranophosphate