title: First successful design of semi-IPN hydrogel-silver nanocomposites: a facile approach for antibacterial application.
abstract: Semi-IPN hydrogels in which poly(vinyl pyrrolidone) (PVP) chains were physically dispersed throughout poly(acrylamide) (PAM) gel networks were synthesized. These semi-IPN hydrogel networks can act as excellent nanoreactors for producing and stabilizing metal nanoparticles. The current methodology allows us to entrap metal nanoparticles throughout hydrogel networks via PVP chains. An optimized semi-IPN hydrogel formulation was found to produce silver nanoparticles, ca. 3-5 nm. The synthesized semi-IPN hydrogel-silver nanocomposites were fully characterized by using UV-vis, X-ray diffraction (XRD), thermogravimetric analysis (TGA), scanning electron microscopy (SEM), and transmission electron microscopy (TEM). The developed semi-IPN hydrogel-silver nanocomposite (SHSNC) was evaluated for preliminary antibacterial applications.
authors.affiliation: Department of Polymer Science and Technology, Sri Krishnadevaraya University, Anantapur 515003, India.
authors.forename: P S K
authors.initials: PS
authors.lastname: Murthy
authors.forename: Y
authors.initials: Y
authors.lastname: Murali Mohan
authors.forename: K
authors.initials: K
authors.lastname: Varaprasad
authors.forename: B
authors.initials: B
authors.lastname: Sreedhar
authors.forename: K
authors.initials: K
authors.lastname: Mohana Raju
mesh_terms: D000180:Acrylic Resins / Q000737:chemistry; D000900:Anti-Bacterial Agents / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology*; D004926:Escherichia coli / Q000187:drug effects*; D020136:Hydrogel, Polyethylene Glycol Dimethacrylate / Q000138:chemical synthesis / Q000737:chemistry*; D053768:Metal Nanoparticles / Q000737:chemistry*; D008826:Microbial Sensitivity Tests; D008855:Microscopy, Electron, Scanning; D010316:Particle Size; D011205:Povidone / Q000737:chemistry; D012834:Silver / Q000737:chemistry* / Q000494:pharmacology; D017550:Spectroscopy, Fourier Transform Infrared; D013499:Surface Properties; D013696:Temperature; D013818:Thermogravimetry; D014961:X-Ray Diffraction; D000099166:Polyacrylamides
chemical_list: D000180:Acrylic Resins; D000900:Anti-Bacterial Agents; D020136:Hydrogel, Polyethylene Glycol Dimethacrylate; D011205:Povidone; D012834:Silver; D000099166:Polyacrylamides