title: [Non-invasive detection for intracranial high pressure with FVEP picked-up by independent component analysis].
abstract: Although the detection of intracranial pressure (ICP) is an important precondition for diagnosing intracranial diseases, yet the detection method prevalently used in clinical practice is still invasive. This study is aimed at finding a non-invasive method for effective detection of the variation of patient's ICP so as to release the patient from bodily pain and to provide the doctor with evidences for giving medicine. Based on analyzing and comparing several existing non-invasive ICP detection methods, we have found the linear relationship of flash visual evoked potential (FVEP) with intracranial medium and high pressure by using the statistics obtained from a number of clinical experiments. The FVEP can be picked up effectively by independent component analysis, while the potential latency corresponding to the wave crest of III wave in the VEP waveform picked-up is linearly related to intracranial pressure, thus obtaining ICP from the III wave of FVEP is possible.
authors.affiliation: College of Biomedical Engineering, Chongqing University, Chongqing 400030, China.
authors.forename: Xi
authors.initials: X
authors.lastname: Wu
authors.forename: Zhong
authors.initials: Z
authors.lastname: Ji
mesh_terms: D005074:Evoked Potentials, Visual / Q000502:physiology*; D006801:Humans; D019586:Intracranial Hypertension / Q000175:diagnosis* / Q000503:physiopathology; D007427:Intracranial Pressure / Q000502:physiology*; D008991:Monitoring, Physiologic / Q000379:methods*; D012815:Signal Processing, Computer-Assisted