Rosai Dorfman disease--a clinico-pathological presentation.
Rosai Dorfman disease (RDD) or sinus histiocytosis with massive lymphadenopathy (SHML) is a rare disorder that typically manifests as lymphadenopathy and systemic symptoms. The authors report a 45 year old lady who presented with nasal mass and generalised lymphadenopathy. Histopathological examination demonstrated lymphophagocytosis (emperipolesis) consistent with a diagnosis of RDD. The clinical and histologic aspects of the disease are discussed as a rare cause of generalised lymphadenopathy.
Mehrotra
S
S
Department of Medicine, King George's Medical University, Lucknow.
Ather
S
S
Gupta
P
P
Mehrotra
B
B
D005260:Female; D015618:Histiocytosis, Sinus / Q000175:diagnosis / Q000276:immunology / Q000473:pathology*; D006801:Humans; D008206:Lymphatic Diseases / Q000175:diagnosis / Q000473:pathology*; D008875:Middle Aged