title: In vitro susceptibility testing of dermatophytes isolated from pediatric cases in Nigeria against five antifungals.
abstract: The antifungal activities of itraconazole, ketoconazole, fluconazole, terbinafine and griseofulvin were tested by broth microdilution methods against 71 isolates of dermatophytes isolated from Nigerian children. Most drugs were very active against all the dermatophytes and the MIC 90 ranged from 0.03 to 8.0 microg/mL. This appears to be the first documented data on the antifungal susceptibility testing of isolates of dermatophytes from Nigerian children.
authors.affiliation: Department of Microbiology, University of Nigeria, Nsukka, Nigeria. newezemeka@yahoo.com
authors.forename: E I
authors.initials: EI
authors.lastname: Nweze
authors.forename: C C
authors.initials: CC
authors.lastname: Ogbonna
authors.forename: J I
authors.initials: JI
authors.lastname: Okafor
mesh_terms: D000935:Antifungal Agents / Q000494:pharmacology*; D003883:Arthrodermataceae / Q000187:drug effects*; D002648:Child; D006801:Humans; D007928:Lethal Dose 50; D008826:Microbial Sensitivity Tests / Q000379:methods; D009549:Nigeria
chemical_list: D000935:Antifungal Agents