Isolated orbital endodermal sinus tumor.
OBJECTIVE
To describe the clinical, serologic, histopathologic, and immunohistochemical findings of an isolated endodermal sinus tumor of the orbit in a 1-year-old boy.


METHODS
A retrospective case report and literature review.


RESULTS
The patient was managed by the ophthalmology and oncology services. After the diagnosis was established by serologic analysis and histopathology, the patient underwent chemotherapy.


CONCLUSIONS
Endodermal sinus tumor is a malignant germ-cell tumor that usually involves the gonadal tissue. Primary extragonadal sites occur rarely, and include the orbit. Treatment options include surgical removal and chemotherapy.
Mogaddam
Aliakbar Saber
AS
Department of Ophthalmology (Khatam-Al-Anbia Eye Hospital), Mashhad University of Medical Sciences, Iran. saberaa@mums.ac.ir
Memar
Bahram
B
Aledavood
Amir
A
Eslampoor
Alireza
A
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D014408:Biomarkers, Tumor / Q000032:analysis; D003131:Combined Modality Therapy; D018240:Endodermal Sinus Tumor / Q000000981:diagnostic imaging / Q000473:pathology* / Q000628:therapy; D006801:Humans; D007223:Infant; D008297:Male; D009918:Orbital Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000628:therapy; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed; D000509:alpha-Fetoproteins / Q000032:analysis
C097353:AFP protein, human; D014408:Biomarkers, Tumor; D000509:alpha-Fetoproteins