[Postoperative nausea and vomiting after laparoscopic cholecystectomy under total intravenous anesthesia using propofol combined with fentanyl or pentazocine].
BACKGROUND
The aim of this study was to compare the incidence of postoperative nausea and vomiting (PONV) in propofol-anesthetized patients receiving either fentanyl or pentazocine as opioid supplement.


METHODS
Sixty-seven patients scheduled for laparoscopic cholecystectomy were analyzed retrospectively. Patients were classified into two groups according to opioid supplement under propofol-anesthesia; pentazocine group (n = 26) and fentanyl group (n = 41). Anesthesia was induced with propofol using target controlled infusion method, and was maintained with propofol infusion with pentazocine or fentanyl and intermittent administration of vecuronium with 40% oxygen in air.


RESULTS
The incidence of PONV was 23.1% in fentanyl group and 22.0% in pentazocine group, respectively. The incidence of PONV was not different between the groups. There were no severe complications.


CONCLUSIONS
The incidence of PONV in propofol-anesthetized patients receiving pentazocine as opioid supplement is not different from that in patients receiving fentanyl.
Nonaka
Akihiko
A
Department of Anesthesia, Yamanashi Prefectural Central Hospital, Kofu 400-8506.
Suzuki
Satomi
S
Nagamine
Norimitsu
N
Furuya
Atsushi
A
Abe
Fumiaki
F
D000082:Acetaminophen / Q000008:administration & dosage*; D018686:Anesthetics, Intravenous / Q000008:administration & dosage*; D001241:Aspirin / Q000008:administration & dosage*; D002744:Chlorpheniramine / Q000008:administration & dosage*; D017081:Cholecystectomy, Laparoscopic; D011431:Dextropropoxyphene / Q000008:administration & dosage*; D004338:Drug Combinations; D005260:Female; D005283:Fentanyl / Q000008:administration & dosage*; D006801:Humans; D008297:Male; D009325:Nausea / Q000209:etiology*; D010423:Pentazocine / Q000008:administration & dosage*; D011183:Postoperative Complications; D012189:Retrospective Studies; D014839:Vomiting / Q000209:etiology*
D018686:Anesthetics, Intravenous; D004338:Drug Combinations; C004575:propofan; D000082:Acetaminophen; D002744:Chlorpheniramine; D001241:Aspirin; D010423:Pentazocine; D011431:Dextropropoxyphene; D005283:Fentanyl