Microwave-accelerated or conventionally heated iodination reactions of some aromatic amines, using ortho-periodic acid as the oxidant.
A fast and simple method for the oxidative iodination of some aromatic amines, either under microwave irradiation or conventional heating, is reported, using diiodine and ortho-periodic acid as the oxidant. The reactions were carried out in boiling CH2Cl2 solutions under a reflux condenser. For the microwave assisted reactions, the reaction times were always notably shortened, but the yields were usually less influenced as compared with the conventional method.
Sosnowski
Maciej
M
Faculty of Pharmacy, Medical University, 1 Banacha Street, PL 02-097 Warsaw, Poland.
Skulski
Lech
L
Wolowik
Katarzyna
K
D000588:Amines / Q000737:chemistry* / Q000302:isolation & purification; D054879:Halogenation; D006358:Hot Temperature; D008872:Microwaves; D016877:Oxidants / Q000737:chemistry*; D010504:Periodic Acid / Q000737:chemistry*; D044366:Transition Temperature
D000588:Amines; D016877:Oxidants; D010504:Periodic Acid