title: Radiation-induced mandibular adult spindle cell rhabdomyosarcoma.
abstract: Spindle cell rhabdomyosarcoma (RMS), a variant of embryonal RMS, is a rare tumour, especially in adults. Imaging techniques are used to evaluate the extent of the tumour whereas a biopsy is required to make the final diagnosis. In this article we describe a case of mandibular Spindle cell RMS in a previously irradiated field in a 56-year-old male, and discuss the clinicopathologic and imaging findings. Although the aetiology is still unclear, this case suggests that previous radiation therapy can be a causal factor.
authors.affiliation: AZ Sint-Jan AV Brugge, Ruddershove 10, 8000 Brugge, Belgium.
authors.forename: V
authors.initials: V
authors.lastname: Goosens
authors.forename: I
authors.initials: I
authors.lastname: Van den Berghe
authors.forename: C
authors.initials: C
authors.lastname: De Clercq
authors.forename: J
authors.initials: J
authors.lastname: Casselman
mesh_terms: D002294:Carcinoma, Squamous Cell / Q000532:radiotherapy; D006801:Humans; D008297:Male; D008339:Mandibular Neoplasms / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D008875:Middle Aged; D009060:Mouth Floor; D009062:Mouth Neoplasms / Q000532:radiotherapy; D009364:Neoplasm Recurrence, Local; D009381:Neoplasms, Radiation-Induced / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D016609:Neoplasms, Second Primary / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D011878:Radiotherapy / Q000009:adverse effects*; D018233:Rhabdomyosarcoma, Embryonal / Q000209:etiology* / Q000473:pathology / Q000601:surgery