Genomic diversity in Helicobacter and related organisms.
The human gastric pathogen Helicobacter pylori possesses an enormous genomic plasticity and diversity that facilitates host adaptation. Despite the ancient association with its human host, this epsilon-proteobacterium can cause gastritis, ulcers and gastric cancer. Here we focus on multiple aspects of the genome level biology, from population genomics to re-evaluating the genus definition.
Linz
Bodo
B
Department of Molecular Biology, Max-Plank Institute for Infection Biology, Berlin, Germany.
Schuster
Stephan C
SC
D000818:Animals; D019143:Evolution, Molecular; D016680:Genome, Bacterial; D023281:Genomics / Q000379:methods*; D016998:Helicobacter / Q000145:classification / Q000235:genetics* / Q000502:physiology; D016480:Helicobacter pylori / Q000145:classification / Q000235:genetics; D006801:Humans; D015398:Signal Transduction