title: Epilepsy associated with shaken baby syndrome.
abstract: OBJECTIVE
  The shaken baby syndrome (SBS) is an important cause of developmental delay in infants. Epileptic seizures are a common feature of this syndrome. The aim if this study is to analyse the impact of the early and late seizures disorder.
  
  
  METHODS
  We have retrospectively reviewed the clinical and electrophysiological findings in a series of 404 children hospitalised with SBS.
  
  
  RESULTS
  In the acute phase, clinical epileptic seizures of various semiologies were found in 73% of the infants. Only 11% of the children had a normal EEG on admission. A poor outcome was found in 88% of the children in case of persisting EEG anomalies despite anti-epileptic treatment with 48% mortality in these patients. The development of refractory epilepsy was also associated with a poor outcome in this series. In fact 96% of the children with seizure recurrence had behavioural problems.
  
  
  CONCLUSIONS
  The early recognition and subsequent management of these seizures is vital to prevent further neurological injury. Delayed or recurrent epileptic seizures may occur with a different semiology to the seizures in the acute phase and are also associated with a poor prognosis.
authors.affiliation: Department of Pediatric Neurosurgery, Hôpital Necker Enfants Malades, 149 rue de Sèvres, 75015, Paris, France. marie.bourgeois@nck.aphp.fr
authors.forename: Marie
authors.initials: M
authors.lastname: Bourgeois
authors.forename: Federico
authors.initials: F
authors.lastname: Di Rocco
authors.forename: Matthew
authors.initials: M
authors.lastname: Garnett
authors.forename: Brigitte
authors.initials: B
authors.lastname: Charron
authors.forename: Nathalie
authors.initials: N
authors.lastname: Boddaert
authors.forename: Christine
authors.initials: C
authors.lastname: Soufflet
authors.forename: Thomas
authors.initials: T
authors.lastname: Roujeau
authors.forename: Michel
authors.initials: M
authors.lastname: Zerah
authors.forename: Christian
authors.initials: C
authors.lastname: Sainte-Rose
authors.forename: Perrine
authors.initials: P
authors.lastname: Plouin
authors.forename: Dominique
authors.initials: D
authors.lastname: Renier
mesh_terms: D004569:Electroencephalography; D004827:Epilepsy / Q000209:etiology* / Q000473:pathology / Q000503:physiopathology; D006801:Humans; D007223:Infant; D008279:Magnetic Resonance Imaging; D012189:Retrospective Studies; D038642:Shaken Baby Syndrome / Q000150:complications* / Q000473:pathology / Q000503:physiopathology; D014057:Tomography, X-Ray Computed