Glycodynamers: dynamic analogs of arabinofuranoside oligosaccharides.
Dynamic analogs of alpha-(1-->5)-D-oligoarabinofuranosides were prepared by oxime polycondensation. These equilibrium polymers were characterized by (1)H NMR studies, NMR DOSY, and MALDI mass spectrometry. Their reversibility under mild acidic conditions was demonstrated by component exchange reaction followed by (1)H NMR studies. Their size and composition can be tuned by component exchange emphasizing their constitutionally dynamic character. They represent dynamic versions of biopolymers, biodynamers.
Ruff
Yves
Y
Institut de Science et d'Ingénierie Supramoléculaires, Université Louis Pasteur, BP 70028, 67083 Strasbourg, France.
Lehn
Jean-Marie
JM
D001089:Arabinose / Q000031:analogs & derivatives* / Q000737:chemistry; D002236:Carbohydrate Conformation; D005944:Glucosamine / Q000737:chemistry; D006027:Glycosides / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D009844:Oligosaccharides / Q000138:chemical synthesis / Q000737:chemistry*; D010091:Oximes / Q000737:chemistry*; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
D006027:Glycosides; D009844:Oligosaccharides; D010091:Oximes; C431714:arabinofuranose; D001089:Arabinose; D005944:Glucosamine