Differentiation of postembryonic skin endothelial cells.
Specific cell markers for selective isolation and growth of cells from the lymphatic and vascular systems have increased our understanding of the structure-function relationships of both systems. Using these markers, a subset of blood vessel endothelial cells (BECs) with the properties of lymphatic endothelial cells (LECs) has been identified in psoriasis and eczema. The differentiation potential of BECs and LECs in vivo and in vitro is reviewed.
Karasek
Marvin
M
Department of Dermatology, Stanford University, Stanford, California 94305-5168, USA. marvek@stanford.edu
D000818:Animals; D001808:Blood Vessels / Q000166:cytology / Q000378:metabolism; D002454:Cell Differentiation; D004485:Eczema / Q000378:metabolism / Q000473:pathology*; D042783:Endothelial Cells / Q000166:cytology* / Q000378:metabolism; D006801:Humans; D007249:Inflammation; D008198:Lymph Nodes / Q000473:pathology*; D008954:Models, Biological; D011565:Psoriasis / Q000378:metabolism / Q000473:pathology*; D012867:Skin / Q000473:pathology*; D012871:Skin Diseases / Q000175:diagnosis / Q000378:metabolism / Q000473:pathology; D012878:Skin Neoplasms / Q000276:immunology