A general synthesis of tris-indole derivatives as potential iron chelators.
The development of a novel route for the synthesis of a new class of compounds is described. The first tripodal, tris-indole amines are prepared by straightforward routes.
Sears
R Bryan
RB
Department of Chemistry, Georgia Southern University, P.O. Box 8064, Statesboro, Georgia 30460, USA.
Carpenter
Russell A
RA
Whitlock
Christine R
CR
D000588:Amines / Q000138:chemical synthesis; D007211:Indoles / Q000138:chemical synthesis*; D007502:Iron Chelating Agents / Q000138:chemical synthesis*; D008954:Models, Biological; D013696:Temperature; D044366:Transition Temperature; D014325:Tromethamine / Q000031:analogs & derivatives* / Q000737:chemistry*
D000588:Amines; D007211:Indoles; D007502:Iron Chelating Agents; D014325:Tromethamine