title: Concurrent syringomyelia and intradural extramedullary tuberculoma as late complications of tuberculous meningitis.
abstract: Tuberculous meningitis (TBM) is a common presentation of extrapulmonary tuberculosis. TBM is associated with many complications. However, concurrent syringomyelia and intradural extramedullary tuberculoma occurring in a patient treated for TBM is rare. Only one such case has been reported earlier. A 27-year-old woman presented with paraparesis of 2 months duration. She had been treated for TBM 8 months earlier. She was found to have an extensive syringomyelia from C2 to the conus medullaris and an intradural extramedullary tuberculoma at the lower thoracic levels. At surgery, a thick, granulomatous lesion was found in the intradural extramedullary plane. Following excision of the granulomatous lesion, a syringostomy was done. The patient was treated with antituberculous drugs and steroids. Six months after treatment, there was no significant change in her neurological status. Concurrent syringomyelia and intradural extramedullary tuberculoma should be entertained in the differential diagnosis when a patient presents with myelopathy following TBM. The pathogenesis of syringomyelia in this condition is discussed.
authors.affiliation: Deparment of Neurosurgery, Madurai Medical College, Madurai, India. drnmuthukumar@yahoo.com
authors.forename: N
authors.initials: N
authors.lastname: Muthukumar
authors.forename: V
authors.initials: V
authors.lastname: Sureshkumar
mesh_terms: D000293:Adolescent; D000995:Antitubercular Agents / Q000627:therapeutic use; D005242:Fecal Incontinence / Q000209:etiology; D005260:Female; D006099:Granuloma / Q000473:pathology; D006801:Humans; D007801:Langerhans Cells / Q000473:pathology; D008279:Magnetic Resonance Imaging; D018908:Muscle Weakness / Q000209:etiology; D019635:Neurosurgical Procedures; D020335:Paraparesis / Q000209:etiology; D013256:Steroids / Q000627:therapeutic use; D013595:Syringomyelia / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D014057:Tomography, X-Ray Computed; D016862:Tuberculoma, Intracranial / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D014390:Tuberculosis, Meningeal / Q000150:complications* / Q000473:pathology / Q000601:surgery
chemical_list: D000995:Antitubercular Agents; D013256:Steroids