title: Time-varying cortical connectivity by adaptive multivariate estimators applied to a combined foot-lips movement.
abstract: In this paper we propose the use of an adaptive multivariate approach to define time-varying multivariate estimators based on the Directed Transfer Function (DTF) and the Partial Directed Coherence (PDC). DTF and PDC are frequency-domain estimators that are able to describe interactions between cortical areas in terms of the concept of Granger causality. Time-varying DTF and PDC were obtained by the adaptive recursive fit of an MVAR model with time-dependent parameters, by means of a generalized recursive least-square (RLS) algorithm, taking into consideration a set of EEG epochs. Such estimators are able to follow rapid changes in the connectivity between cortical areas during an experimental task. We provide an application to the cortical estimations obtained from high resolution EEG data, recorded from a group of healthy subject during a combined foot-lips movement, and present the time-varying connectivity patterns resulting from the application of both DTF and PDC. Two different cortical networks were detected, one constant across the task and the other evolving during the preparation of the joint movement.
authors.affiliation: Dep. of Human Physiology and Pharmacology of the Univ. of Rome La Sapienza, Rome, Italy. laura.astolfi@uniroma1.it
authors.forename: L
authors.initials: L
authors.lastname: Astolfi
authors.forename: F
authors.initials: F
authors.lastname: Cincotti
authors.forename: D
authors.initials: D
authors.lastname: Mattia
authors.forename: F
authors.initials: F
authors.lastname: De Vico Fallani
authors.forename: A
authors.initials: A
authors.lastname: Colosimo
authors.forename: S
authors.initials: S
authors.lastname: Salinari
authors.forename: M G
authors.initials: MG
authors.lastname: Marciani
authors.forename: M
authors.initials: M
authors.lastname: Ursino
authors.forename: M
authors.initials: M
authors.lastname: Zavaglia
authors.forename: W
authors.initials: W
authors.lastname: Hesse
authors.forename: H
authors.initials: H
authors.lastname: Witte
authors.forename: F
authors.initials: F
authors.lastname: Babiloni
mesh_terms: D000328:Adult; D001931:Brain Mapping / Q000379:methods; D002540:Cerebral Cortex / Q000502:physiology*; D004569:Electroencephalography / Q000379:methods; D005260:Female; D005528:Foot / Q000502:physiology*; D006801:Humans; D008046:Lip / Q000502:physiology*; D008297:Male; D008954:Models, Biological; D009043:Motor Activity / Q000502:physiology*; D009415:Nerve Net / Q000502:physiology*