title: Lifetime prevalence of infertility and infertility treatment in the UK: results from a population-based survey of reproduction.
abstract: BACKGROUND
  The aim of this study was to investigate the prevalence of infertility and the use of infertility treatment among women aged 40-55 years.
  
  
  METHODS
  Population-based postal questionnaire survey of UK women. Over 60,000 women randomly sampled from the 2001 electoral roll were sent a questionnaire, and those aged 55 years and under who had ever been pregnant or tried to achieve a pregnancy (n = 6584) were asked to provide a reproductive history.
  
  
  RESULTS
  Overall, 2.4% of women aged 40-55 years had unresolved infertility with no pregnancies, and a further 1.9% had been pregnant but not achieved a live birth. The prevalence of unresolved fertility did not differ among birth cohorts. Sixteen percent of women reported ever consulting a doctor because of infertility and 8% reported receiving treatment to conceive. Across the whole sample, 4.2% of women reported that they had achieved at least one pregnancy as a result of treatment. Compared with earlier birth cohorts, women born later were more likely to report consultations (18% versus 13%) and treatment (9% versus 6%) for infertility, and pregnancies as a result of infertility treatment (6.7% versus 2.7%). Among those who reported medical consultations, women born more recently first consulted at a later age compared with those born earlier.
  
  
  CONCLUSIONS
  Although both the number of women seeking medical care for infertility and the proportion reporting pregnancies as a result of infertility treatment has increased, there is no evidence to support an overall increase in unresolved infertility over the past 15 years. The vast majority of women aged 40-55 who reported difficulties conceiving did have a child, or children, at some point in their lives.
authors.affiliation: Centre for Research in Primary and Community Care, University of Hertfordshire, Hatfield, Hertfordshire AL10 9AB, UK. laura.oakley@lshtm.ac.uk
authors.forename: L
authors.initials: L
authors.lastname: Oakley
authors.forename: P
authors.initials: P
authors.lastname: Doyle
authors.forename: N
authors.initials: N
authors.lastname: Maconochie
mesh_terms: D000328:Adult; D015331:Cohort Studies; D005260:Female; D006801:Humans; D007247:Infertility, Female / Q000453:epidemiology* / Q000628:therapy*; D008875:Middle Aged; D011247:Pregnancy; D018873:Pregnancy Rate; D015995:Prevalence; D027724:Reproductive Techniques, Assisted / Q000706:statistics & numerical data; D011795:Surveys and Questionnaires; D016896:Treatment Outcome; D006113:United Kingdom / Q000453:epidemiology