Networking particles over distance using oligonucleotide-based devices.
Microparticles covered with DNA-based computing elements that sense inputs and release oligonucleotides as outputs could be used to construct autonomous networks with increasingly complex functions. We demonstrate cascades of particles with up to three layers and a nonlinear network with an AND gate hub. In order to establish functional networks, particles do not have to be in direct physical contact.
Yashin
Ruslan
R
NSF Center for Molecular Cybernetics, Division of Experimental Therapeutics, Department of Medicine, Columbia University, New York City, New York 10032, USA.
Rudchenko
Sergei
S
Stojanovic
Milan N
MN
D001483:Base Sequence; D009841:Oligonucleotides / Q000737:chemistry*
D009841:Oligonucleotides