Palliative care pharmacotherapy literature summaries and analyses.
Timely and important studies are reviewed and commentaries provided by leading palliative care clinicians. Symptoms and treatment side effects addressed in this issue are: cardiovascular risk due to NSAIDs or COX-2 inhibitors; prolongation of the QT interval due to methadone use; depression and its treatment with scopolamine; adverse drug reactions related to cardiovascular medications, and their association with ethnicity; and medication nonadherence in Medicare enrollees due to cost considerations.
Abernethy
Amy P
AP
Duke University Medical Center, Durham, NC 27710, USA. amy.abernethy@duke.edu
Nixon
Alan
A
Fine
Perry G
PG
Peppin
John F
JF
Crossno
R J
RJ
Bull
Janet
J
D000701:Analgesics, Opioid / Q000009:adverse effects; D002318:Cardiovascular Diseases / Q000139:chemically induced; D002986:Clinical Trials as Topic; D052246:Cyclooxygenase 2 Inhibitors / Q000009:adverse effects; D003865:Major Depressive Disorder / Q000188:drug therapy*; D006801:Humans; D008691:Methadone / Q000009:adverse effects; D018727:Muscarinic Antagonists / Q000627:therapeutic use*; D010146:Pain / Q000188:drug therapy*; D010166:Palliative Care / Q000379:methods*; D012601:Scopolamine / Q000627:therapeutic use*
D000701:Analgesics, Opioid; D052246:Cyclooxygenase 2 Inhibitors; D018727:Muscarinic Antagonists; D012601:Scopolamine; D008691:Methadone