Synthesis of some novel 11b-substituted pyrimido[6,1-a]-isoquinoline derivatives.
A series of novel 11b-substituted 1,6,7,11b-tetrahydropyrimido[6,1-a]- isoquinoline-2,4-diones and 4-thioxo-1,3,4,6,7,11b-hexahydropyrimido[6,1-a]isoquinolin-2- ones were synthesized, utilizing two alternative strategies for ring closure of tetrahydroisoquinoline intermediates obtained from N-phenethyl enaminones.
Angelov
Plamen A
PA
Department of Organic Chemistry, University of Plovdiv, 24 Tsar Asen str., 4000 Plovdiv, Bulgaria. angelov@argon.acad.bg
Ivanov
Iliyan I
II
Venkov
Atanas P
AP
D000465:Algorithms; D009682:Magnetic Resonance Spectroscopy; D008956:Models, Chemical; D011522:Protons; D011743:Pyrimidines / Q000138:chemical synthesis / Q000737:chemistry*; D044005:Tetrahydroisoquinolines / Q000138:chemical synthesis* / Q000737:chemistry
D011522:Protons; D011743:Pyrimidines; D044005:Tetrahydroisoquinolines