Clinical relevance of relative receptor binding affinity: quetiapine and ziprasidone as examples.
Preskorn
Sheldon H
SH
Department of Psychiatry, University of Kansas School of Medicine-Wichita, USA.
D014150:Antipsychotic Agents / Q000378:metabolism* / Q000493:pharmacokinetics / Q000494:pharmacology; D019540:Area Under Curve; D003987:Dibenzothiazepines / Q000378:metabolism* / Q000493:pharmacokinetics / Q000494:pharmacology; D004305:Dose-Response Relationship, Drug; D006801:Humans; D010879:Piperazines / Q000378:metabolism* / Q000493:pharmacokinetics / Q000494:pharmacology; D011485:Protein Binding; D000069348:Quetiapine Fumarate; D017981:Receptors, Neurotransmitter / Q000378:metabolism*; D013844:Thiazoles / Q000378:metabolism* / Q000493:pharmacokinetics / Q000494:pharmacology
D014150:Antipsychotic Agents; D003987:Dibenzothiazepines; D010879:Piperazines; D017981:Receptors, Neurotransmitter; D013844:Thiazoles; D000069348:Quetiapine Fumarate; C092292:ziprasidone