title: Effectiveness of green tea on weight reduction in obese Thais: A randomized, controlled trial.
abstract: This study was undertaken to investigate the effects of green tea on weight reduction in obese Thais. A randomized, controlled trial involving 60 obese subjects (body mass index, BMI > 25 kg/m2) was conducted. All subjects consumed a Thai diet containing 3 meals (8373.6 kJ/day) for 12 weeks, prepared by the Nutritional Unit at Srinagarind Hospital. The diet contained 65% carbohydrates, 15% protein, and 20% fat. Body weight, BMI, body composition, resting energy expenditure, and substrate oxidation were measured at baseline, and during weeks 4, 8, and 12 of the study. Serum levels of leptin and urine VMA were measured at baseline and during the 12th week. Differences over time and between the treatments (green tea or placebo) over time were determined using two-factor ANOVA with repeated measures. In comparing the two groups, differences in weight loss were 2.70, 5.10, and 3.3 kg during the 4th, 8th, and 12th weeks of the study, respectively. At the 8th and 12th weeks of the study, body weight loss was significantly different (P < 0.05). At the 8th week, the difference in resting energy expenditure was 183.38 kJ/day (P < 0.001), the difference in the respiratory quotient was 0.02 (P < 0.05), and no significant differences existed in satiety score, food intake, or physical activity. Urine VMA was significantly different in the 12th week of the study (P < 0.05). We conclude that green tea can reduce body weight in obese Thai subjects by increasing energy expenditure and fat oxidation.
authors.affiliation: Department of Physiology, Faculty of Medicine, Khon Kaen University, 40002, Thailand. aparad@kku.ac.th <aparad@kku.ac.th>
authors.forename: Paradee
authors.initials: P
authors.lastname: Auvichayapat
authors.forename: Montira
authors.initials: M
authors.lastname: Prapochanung
authors.forename: Oratai
authors.initials: O
authors.lastname: Tunkamnerdthai
authors.forename: Bung-orn
authors.initials: BO
authors.lastname: Sripanidkulchai
authors.forename: Narong
authors.initials: N
authors.lastname: Auvichayapat
authors.forename: Bandit
authors.initials: B
authors.lastname: Thinkhamrop
authors.forename: Soontorn
authors.initials: S
authors.lastname: Kunhasura
authors.forename: Srisuda
authors.initials: S
authors.lastname: Wongpratoom
authors.forename: Supat
authors.initials: S
authors.lastname: Sinawat
authors.forename: Pranithi
authors.initials: P
authors.lastname: Hongprapas
mesh_terms: D000328:Adult; D000704:Analysis of Variance; D001794:Blood Pressure / Q000187:drug effects / Q000502:physiology; D001823:Body Composition / Q000187:drug effects; D015992:Body Mass Index; D004311:Double-Blind Method; D004734:Energy Metabolism / Q000187:drug effects; D005260:Female; D006339:Heart Rate / Q000187:drug effects / Q000502:physiology; D006801:Humans; D020738:Leptin / Q000378:metabolism; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000178:diet therapy* / Q000378:metabolism / Q000503:physiopathology; D010147:Pain Measurement; D013662:Tea / Q000737:chemistry; D013785:Thailand; D013997:Time Factors; D014642:Vanilmandelic Acid / Q000652:urine; D015431:Weight Loss / Q000187:drug effects* / Q000502:physiology
chemical_list: D020738:Leptin; D013662:Tea; D014642:Vanilmandelic Acid