title: Redox-induced conformational alteration of n,n-diarylamides.
abstract: We constructed a novel molecular conformational alteration system with an N-aryl-N-phenylacetamide structure, in which the N-aryl group consists of a hydroquinone-p-quinone system as a redox-dependent aromatic trigger. The amide conformation depended on the oxidation state of the aryl group, and the two states (compounds 2 and 3) were reversibly converted to each other by redox reactions. Such compounds would be applied as useful structural units for external stimulus-responsive control on the shape and function of large molecules or supramolecules.
authors.affiliation: Showa Pharmaceutical University, 3-3165 Higashi-Tamagawagakuen, Machida, Tokyo 194-8543, Japan. iokamoto@ac.jp
authors.forename: Iwao
authors.initials: I
authors.lastname: Okamoto
authors.forename: Ryu
authors.initials: R
authors.lastname: Yamasaki
authors.forename: Mika
authors.initials: M
authors.lastname: Sawamura
authors.forename: Takako
authors.initials: T
authors.lastname: Kato
authors.forename: Naomi
authors.initials: N
authors.lastname: Nagayama
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Takeya
authors.forename: Osamu
authors.initials: O
authors.lastname: Tamura
authors.forename: Hyuma
authors.initials: H
authors.lastname: Masu
authors.forename: Isao
authors.initials: I
authors.lastname: Azumaya
authors.forename: Kentaro
authors.initials: K
authors.lastname: Yamaguchi
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Kagechika
authors.forename: Aya
authors.initials: A
authors.lastname: Tanatani
mesh_terms: D000577:Amides / Q000737:chemistry*; D008958:Models, Molecular; D008968:Molecular Conformation; D010084:Oxidation-Reduction
chemical_list: D000577:Amides