title: [Management of digital ulcers from systemic scleroderma].
abstract: Digital ulcers are a frequent event in systemic scleroderma. Despite their frequency, there is currently no consensus about their management. Curative treatment is based on local care and vasodilatating agents, together with the prevention of superinfection. Preventive measures require the elimination of risk factors and reeducation. For multiple recurrent ulcers, endothelin receptor inhibitors or prostacyclin derivatives are also prescribed. Surgery is useful in the case of substantial retraction or bothersome calcifications. In all cases, calcium channel blockers are continued.
authors.affiliation: Service de dermatologie-allergologie, AP-HP, Hôpital Tenon, F-75020 Paris, France. camille.frances@tnn.aphp.fr
authors.forename: Camille
authors.initials: C
authors.lastname: Francès
authors.forename: Yannick
authors.initials: Y
authors.lastname: Allanore
authors.forename: Jean
authors.initials: J
authors.lastname: Cabane
authors.forename: Patrick
authors.initials: P
authors.lastname: Carpentier
authors.forename: Christian
authors.initials: C
authors.lastname: Dumontier
authors.forename: Eric
authors.initials: E
authors.lastname: Hachulla
authors.forename: Pierre-Yves
authors.initials: PY
authors.lastname: Hatron
authors.forename: Dan
authors.initials: D
authors.lastname: Lipsker
authors.forename: Sylvie
authors.initials: S
authors.lastname: Meaume
authors.forename: Luc
authors.initials: L
authors.lastname: Mouthon
authors.forename: Patricia
authors.initials: P
authors.lastname: Senet
authors.forename: Jean
authors.initials: J
authors.lastname: Sibilia
mesh_terms: D000698:Analgesia; D000779:Anesthetics, Local / Q000627:therapeutic use; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001424:Bacterial Infections / Q000175:diagnosis / Q000517:prevention & control; D047070:Bandages, Hydrocolloid; D004599:Electric Stimulation Therapy; D005385:Fingers; D006801:Humans; D012595:Scleroderma, Systemic / Q000150:complications* / Q000628:therapy*; D012883:Skin Ulcer / Q000209:etiology / Q000628:therapy*; D014665:Vasodilator Agents / Q000627:therapeutic use
chemical_list: D000779:Anesthetics, Local; D000900:Anti-Bacterial Agents; D014665:Vasodilator Agents