title: [Bone metastases].
abstract: Bone metastases are a frequent condition leading to fractures, hypercalcaemia and spinal compression. The treatment will depend on the possibility to treat the cancer. Secondly local treatment should be considered. To relief pain radiotherapy, given as 1 fraction with 8 Gy, is an effective treatment. Radiotherapy can also be used to treat complications from the metastasis. The use of bisphosphonates is now established in the treatment of breast cancer with bone metastasis to prevent complications from bone metastasis. Surgery is a growing possibility both as treatment of manifest fractures and prophylactic. Selection of patients to surgery is important to keep complication rate low.
authors.affiliation: Arhus Universitetshospital, Arhus Sygehus, Onkologisk Afdeling. abjen@as.aaa.dk
authors.forename: Anders Bonde
authors.initials: AB
authors.lastname: Jensen
authors.forename: Claus
authors.initials: C
authors.lastname: Kamby
authors.forename: Bjarne
authors.initials: B
authors.lastname: Hansen
authors.forename: Johnny
authors.initials: J
authors.lastname: Keller
mesh_terms: D001859:Bone Neoplasms / Q000517:prevention & control / Q000556:secondary* / Q000628:therapy; D004164:Diphosphonates / Q000627:therapeutic use; D005598:Fractures, Spontaneous / Q000209:etiology / Q000517:prevention & control / Q000601:surgery; D006801:Humans; D009369:Neoplasms / Q000150:complications / Q000628:therapy; D010146:Pain / Q000209:etiology / Q000517:prevention & control; D059408:Pain Management; D010166:Palliative Care / Q000379:methods
chemical_list: D004164:Diphosphonates