title: Reactivity of 4-tert-butyldimethylsiloxy-1,2,3,6-tetrahydropyridines with hydrazines.
abstract: The reactivity of 6-(nitrophenyl or trimethoxyphenyl)-4-tert-butyldimethyl- siloxy-1,2,3,6-tetrahydropyridine derivatives with hydrazines under acid conditions is described. The structure of the products isolated - hydrazones, pyrazolines or pyridazinones - depended on the conditions used. In addition, a systematic study of the reaction outcomes was carried out by introducing variations on the substituents of the tetrahydropyridine ring.
authors.affiliation: Laboratorio de Química Orgánica y Farmacéutica, Facultad de Farmacia, Campus Miguel de Unamuno, 37007 Salamanca, Spain.
authors.forename: Javier
authors.initials: J
authors.lastname: Figueroa
authors.forename: Esther
authors.initials: E
authors.lastname: Caballero
authors.forename: Pilar
authors.initials: P
authors.lastname: Puebla
authors.forename: Fernando
authors.initials: F
authors.lastname: Tomé
authors.forename: Manuel
authors.initials: M
authors.lastname: Medarde
mesh_terms: D002247:Carbon Isotopes; D006834:Hydrazines / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D011522:Protons; D011725:Pyridines / Q000737:chemistry*; D012833:Siloxanes / Q000737:chemistry*
chemical_list: D002247:Carbon Isotopes; D006834:Hydrazines; D011522:Protons; D011725:Pyridines; D012833:Siloxanes