Effect of myo-inositol on convulsions induced by pentylenetetrazole and kainic acid in rats.
We studied the effect of myo-inositol on pentylenetetrazole and kainic acid-induced seizures in rats. Myo-inositol significantly reduced seizure activity.
Solomonia
R
R
I. S. Beritashvili Institute of Physiology, Georgian Academy of Sciences, Tbilisi.
Nozadze
M
M
Kuchiashvili
N
N
Bolkvadze
T
T
Kiladze
M
M
Zhvania
M
M
Kigyradze
T
T
Pkhakadze
V
V
D000818:Animals; D000927:Anticonvulsants / Q000494:pharmacology* / Q000627:therapeutic use; D003292:Convulsants; D007294:Inositol / Q000494:pharmacology* / Q000627:therapeutic use; D007608:Kainic Acid; D010433:Pentylenetetrazole; D051381:Rats; D012640:Seizures / Q000139:chemically induced / Q000188:drug therapy*
D000927:Anticonvulsants; D003292:Convulsants; D007294:Inositol; D007608:Kainic Acid; D010433:Pentylenetetrazole