title: Mammalian sperm chromatin structure and assessment of DNA fragmentation.
abstract: This review article illustrates the biology of mammalian sperm chromatin structure. The possible causes of DNA (deoxyribonucleic acid) fragmentation are discussed. Also available molecular techniques for assessment of mammalian sperm DNA damage are described.
authors.affiliation: Animal Reproduction Laboratory, Animal Sciences Institute, National Agricultural Research Centre, Park Road, Islamabad, 45500, Pakistan. andrabi123@yahoo.com
authors.forename: S M H
authors.initials: SM
authors.lastname: Andrabi
mesh_terms: D000818:Animals; D017209:Apoptosis / Q000235:genetics / Q000502:physiology; D002843:Chromatin / Q000737:chemistry*; D004249:DNA Damage; D053938:DNA Fragmentation; D042003:DNA Packaging / Q000502:physiology; D005821:Genetic Techniques; D006657:Histones / Q000378:metabolism / Q000502:physiology; D006801:Humans; D008297:Male; D009687:Nuclear Proteins / Q000378:metabolism / Q000502:physiology; D018384:Oxidative Stress / Q000235:genetics / Q000502:physiology; D011479:Protamines / Q000378:metabolism; D013094:Spermatozoa / Q000378:metabolism* / Q000648:ultrastructure
chemical_list: D002843:Chromatin; D006657:Histones; D009687:Nuclear Proteins; D011479:Protamines