title: Frequency of risk factors that potentially increase harm from medications in older adults receiving primary care.
abstract: BACKGROUND
  Many circumstances elevate patients, especially older adults, risk for drug-related morbidity and misadventures. Understanding the frequency of these situations can help with the design of initiatives to address or alter these circumstances with the aim of reducing medication therapy-related concerns and associated expenditures.
  
  
  OBJECTIVE
  To describe the frequency of circumstances that may place older adults at higher risk for drug-related morbidity and misadventures in a large sample of elderly patients visiting family medicine clinics.
  
  
  METHODS
  Elderly adults at 7 family medicine practices across Ontario self-completed the 10-item Medication Risk Questionnaire (MRQ).
  
  
  RESULTS
  Surveys were completed by 907 patients, with a mean age of 72.4 (SD 10.7) years and a mean number of 4.8 medical conditions (SD 2.3; min-max: 0-14). Many subjects were taking multiple medications (mean 6.9 (SD 3.8; min-max: 0-21)) and over 90% of respondents reported at least one indicator that potentially increases their risk of drug-related morbidity.
  
  
  CONCLUSIONS
  Number of medications, number of medical conditions and number of daily medication doses were the most frequently observed risks for medication-related issues in this large sample of elderly patients visiting family medicine clinics.
authors.affiliation: Centre for Evaluation of Medicines, St. Joseph's Healthcare, Hamilton, Canada. lmccart@mcmaster.ca
authors.forename: L
authors.initials: L
authors.lastname: McCarthy
authors.forename: L
authors.initials: L
authors.lastname: Dolovich
authors.forename: M
authors.initials: M
authors.lastname: Haq
authors.forename: L
authors.initials: L
authors.lastname: Thabane
authors.forename: J
authors.initials: J
authors.lastname: Kaczorowski
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D003430:Cross-Sectional Studies; D064420:Drug-Related Side Effects and Adverse Reactions; D005260:Female; D006801:Humans; D008297:Male; D008508:Medication Errors / Q000379:methods*; D008875:Middle Aged; D011320:Primary Health Care / Q000379:methods*; D012307:Risk Factors