title: How do adjuvants work? Important considerations for new generation adjuvants.
abstract: In this Commentary, McKee et al. highlight the properties of extrinsic vaccine adjuvants that must be considered to achieve the most protective immune response, as occurs naturally with many intrinsic pathogen-derived adjuvants.
authors.affiliation: HHMI, Integrated Department of Immunology, National Jewish Medical and Research Center, University of Colorado Health Science Center, Denver, CO 80262, USA.
authors.forename: Amy S
authors.initials: AS
authors.lastname: McKee
authors.forename: Michael W
authors.initials: MW
authors.lastname: Munks
authors.forename: Philippa
authors.initials: P
authors.lastname: Marrack
mesh_terms: D000276:Adjuvants, Immunologic / Q000494:pharmacology*; D000818:Animals; D006801:Humans; D007107:Immune System / Q000502:physiology*; D007239:Infections / Q000276:immunology*; D014612:Vaccines / Q000276:immunology*
chemical_list: D000276:Adjuvants, Immunologic; D014612:Vaccines