title: AIDS dementia complex and Hashimoto encephalopathy in a senescent woman.
abstract: AIDS dementia complex is one of the specific infectious dementias, which is rarely seen in senescent (>75 years of age) subjects. Hashimoto encephalopathy has been described as the cause of several neurological and psychiatric syndromes including dementia. The proposed pathophysiological mechanism is an autoimmune reaction to shared, thyroid gland and CNS epitopes with subsequent cerebral dysfunction. We report here the first case of a patient who fulfils both, the criteria for AIDS dementia complex and Hashimoto encephalopathy, yet being unresponsive to steroid therapy. Diagnostic and therapeutic implications are discussed.
authors.affiliation: Division of Geriatric Psychiatry, Central Institute of Mental Health, University of Heidelberg, Mannheim, Germany.
authors.forename: Robert
authors.initials: R
authors.lastname: Waltereit
authors.forename: Gudrun
authors.initials: G
authors.lastname: Schulte-Brochterbeck
authors.forename: Jens
authors.initials: J
authors.lastname: Wiltfang
authors.forename: Lutz
authors.initials: L
authors.lastname: Frölich
mesh_terms: D015526:AIDS Dementia Complex / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D000368:Aged; D014150:Antipsychotic Agents / Q000627:therapeutic use; D015283:Citalopram / Q000627:therapeutic use; D005260:Female; D050031:Hashimoto Disease / Q000150:complications* / Q000188:drug therapy; D006801:Humans; D018967:Risperidone / Q000627:therapeutic use; D017367:Selective Serotonin Reuptake Inhibitors / Q000627:therapeutic use; D016896:Treatment Outcome
chemical_list: D014150:Antipsychotic Agents; D015283:Citalopram; D018967:Risperidone; D017367:Selective Serotonin Reuptake Inhibitors