Acute necrotizing encephalopathy of childhood: report of a Spanish case.
Acute necrotizing encephalopathy of childhood is a rare disease with a broad clinical, radiologic, and biochemical spectrum. In the few postmortem studies published to date, the neuropathologic findings involved symmetric, necrotic brain lesions as the hallmark. Here we report on the clinical and neuropathologic findings of a Spanish child with the most severe form of the disease.
San Millan
Beatriz
B
Department of Neuropathology, University Hospital of Vigo, Meixoeiro, Spain.
Teijeira
Susana
S
Penin
Carmen
C
Garcia
Jose L
JL
Navarro
Carmen
C
D001921:Brain / Q000473:pathology*; D003933:Diagnosis; D005260:Female; D006801:Humans; D007223:Infant; D004684:Leukoencephalitis, Acute Hemorrhagic / Q000000981:diagnostic imaging / Q000378:metabolism / Q000473:pathology*; D011859:Radiography; D013030:Spain