Antiarrhythmic effect of heat adaptation in ischemic and reperfusion injury to the heart.
Study on a model of 6-day dosed adaptation to heat in rats showed that this adaptation decreased the severity of cardiac arrhythmias during ischemic and reperfusion injury. The duration of arrhythmias decreased not only in the ischemic period, but also under conditions of reperfusion. Adaptation delayed the development of arrhythmias during ischemia, decreased the number of animals with late reperfusion arrhythmias, and improved recovery of the heart after ischemia and reperfusion.
Monastyrskaya
E A
EA
Moscow State Medical Stomatology University.
Belkina
L M
LM
Manukhina
E B
EB
Malyshev
I Yu
IY
D000222:Adaptation, Physiological; D000818:Animals; D001145:Arrhythmias, Cardiac / Q000378:metabolism / Q000503:physiopathology*; D006358:Hot Temperature; D017202:Myocardial Ischemia / Q000378:metabolism / Q000503:physiopathology*; D015428:Myocardial Reperfusion Injury / Q000378:metabolism / Q000503:physiopathology*; D009569:Nitric Oxide / Q000096:biosynthesis; D051381:Rats; D013997:Time Factors
D009569:Nitric Oxide