Palladium-catalysed N-annulation routes to indoles: the synthesis of indoles with sterically demanding N-substituents, including demethylasterriquinone A1.
Tandem palladium-catalysed aryl and alkenyl C-N bond formation allows the synthesis of a variety of indoles bearing sterically demanding N-substituents, including the natural product demethylasterriquinone A1.
Fletcher
Anthony J
AJ
Department of Chemistry, University of Oxford, Chemical Research Laboratory, Mansfield Road, Oxford, UK OX1 3TA.
Bax
Matthew N
MN
Willis
Michael C
MC
D001688:Biological Products / Q000737:chemistry; D002384:Catalysis; D007211:Indoles / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D009584:Nitrogen / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry*; D013237:Stereoisomerism
D001688:Biological Products; D007211:Indoles; D010165:Palladium; D009584:Nitrogen