Androgen-independent prostate cancer treated with resection of the solitary metastatic site.
The concept of resection of a solitary metastatic lesion is quite foreign in prostate cancer, as metastases to regional lymph nodes or to other distant sites are most likely suggestive of disseminated disease. The current report demonstrates a very unique case, in whom excision of a solitary pulmonary metastasis has resulted in continued undetectable prostate-specific antigen values over 3 years after resection. Nevertheless, the presence of unusual cases such as this, as well as the work of others, may suggest that surgical excision of solitary or oligometastatic sites could at least be considered for the most highly selected and well-informed patients, whose clinical scenario indicates a potential benefit from such an approach.
Pruthi
Raj S
RS
Division of Urologic Surgery, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA. rpruthi@med.unc.edu
Hubbard
J Slade
JS
Kouba
Erik
E
Wallen
Eric
E
D000230:Adenocarcinoma / Q000556:secondary* / Q000601:surgery; D000368:Aged; D005500:Follow-Up Studies; D006801:Humans; D008175:Lung Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary* / Q000601:surgery*; D008297:Male; D009367:Neoplasm Staging; D017430:Prostate-Specific Antigen / Q000097:blood*; D011468:Prostatectomy / Q000379:methods; D011471:Prostatic Neoplasms / Q000175:diagnosis / Q000601:surgery*; D018570:Risk Assessment; D021701:Sentinel Lymph Node Biopsy / Q000379:methods; D020775:Thoracic Surgery, Video-Assisted; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
D017430:Prostate-Specific Antigen