Expanding neuronal layers by the local division of committed precursors.
A general strategy in vertebrate neural development is for neuronal precursors to stop dividing, to begin to differentiate, and then to migrate to their final destination. In this issue of Neuron, however, Godhino et al. provide evidence that some neuronal precursors undergo a terminal symmetric cell division at their final destination to form an entire neuronal layer.
Cayouette
Michel
M
Institut de recherches cliniques de Montréal, Montréal, QC H2W 1R7, Canada. michel.cayouette@ircm.qc.ca
D000818:Animals; D002454:Cell Differentiation / Q000502:physiology; D002455:Cell Division / Q000502:physiology; D002465:Cell Movement / Q000502:physiology; D006801:Humans; D023421:Models, Animal; D009434:Neural Pathways / Q000166:cytology* / Q000196:embryology* / Q000502:physiology; D009474:Neurons / Q000166:cytology / Q000502:physiology*; D012160:Retina / Q000166:cytology* / Q000196:embryology* / Q000502:physiology; D013234:Stem Cells / Q000166:cytology / Q000502:physiology*; D015027:Zebrafish / Q000196:embryology / Q000502:physiology