title: ARWEN: a program to detect tRNA genes in metazoan mitochondrial nucleotide sequences.
abstract: BACKGROUND
  Mitochondrial genomes encode their own transfer RNAs (tRNAs). These are often degenerate in sequence and structure compared to tRNAs in their bacterial ancestors. This is one of the reasons why current tRNA gene predictor programs perform poorly identifying mitochondrial tRNA genes. As a consequence there is a need for a new program with the specific aim of predicting these tRNAs.
  
  
  RESULTS
  In this study, we present the software ARWEN that identifies tRNA genes in metazoan mitochondrial nucleotide sequences. ARWEN detects close to 100% of previously annotated genes.
  
  
  BACKGROUND
  An online version, software for download and test results are available at www.acgt.se/online.html
authors.affiliation: Murdoch University, Perth, Western Australia, Australia.
authors.forename: Dean
authors.initials: D
authors.lastname: Laslett
authors.forename: Björn
authors.initials: B
authors.lastname: Canbäck
mesh_terms: D000465:Algorithms; D000818:Animals; D001483:Base Sequence; D002874:Chromosome Mapping / Q000379:methods*; D008969:Molecular Sequence Data; D012313:RNA / Q000235:genetics*; D000077278:RNA, Mitochondrial; D012343:RNA, Transfer / Q000235:genetics*; D017423:Sequence Analysis, RNA / Q000379:methods*; D012984:Software
chemical_list: D000077278:RNA, Mitochondrial; D012313:RNA; D012343:RNA, Transfer