title: [Acute thrombo-embolic elevated ST infarct in a patient with essential thrombocytosis].
abstract: A 48-year-old man presented with acute chest pain and a greatly increased platelet count. Emergency coronary angiographic revealed thrombotic occlusion of the right coronary artery. Coronary angioplasty and stenting were successfully combined with intracoronary abciximab administration. Due to inadequate postinterventional platelet inhibition an intensified dual antiplatelet therapy with acetylsalicylic acid (ASS) and clopidogrel was applied to prevent stent thrombosis. Due to the thrombo-embolic complication and a platelet count over 1 million/microl a cytoreductive treatment with hydroxyurea was initiated.
authors.affiliation: Medizinische Klinik III, Universitätsklinikum Tübingen, Otfried-Müller-Str. 10, 72076, Tübingen, Deutschland. Christina.Doesch@med.uni-tuebingen.de
authors.forename: C
authors.initials: C
authors.lastname: Doesch
authors.forename: A E
authors.initials: AE
authors.lastname: May
authors.forename: G
authors.initials: G
authors.lastname: Toncar-Pflumm
authors.forename: N
authors.initials: N
authors.lastname: Anders
authors.forename: T
authors.initials: T
authors.lastname: Geisler
authors.forename: S
authors.initials: S
authors.lastname: Kröber
authors.forename: R
authors.initials: R
authors.lastname: Kandolf
authors.forename: M
authors.initials: M
authors.lastname: Gawaz
mesh_terms: D000077284:Abciximab; D015906:Angioplasty, Balloon, Coronary; D000911:Antibodies, Monoclonal / Q000627:therapeutic use; D001707:Biopsy, Needle; D001853:Bone Marrow / Q000473:pathology; D003131:Combined Modality Therapy; D017023:Coronary Angiography; D003328:Coronary Thrombosis / Q000175:diagnosis* / Q000628:therapy; D004562:Electrocardiography; D006801:Humans; D007140:Immunoglobulin Fab Fragments / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D009196:Myeloproliferative Disorders / Q000175:diagnosis / Q000628:therapy; D009203:Myocardial Infarction / Q000175:diagnosis* / Q000628:therapy; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use; D015607:Stents; D013922:Thrombocytosis / Q000175:diagnosis* / Q000628:therapy
chemical_list: D000911:Antibodies, Monoclonal; D007140:Immunoglobulin Fab Fragments; D010975:Platelet Aggregation Inhibitors; D000077284:Abciximab