Conformation families of protein fragments in multidimensional torsion-angle space.
Protein conformation families for automatic model building were determined for dipeptidic, tripeptidic, tetrapeptidic and pentapeptidic fragments. Mapping in n-dimensional conformational space (n = 2, 4 and 6), a conformation-generator method, a deletion-sorting process and a verification procedure were used to calculate the conformational preferences. Torsion angles were harvested from PDB structures with resolutions better than 1.5 A. Statistical weights were calculated for the conformation families.
Pavelcik
Frantisek
F
Department of Chemical Drugs, Faculty of Pharmacy, University of Veterinary and Pharmaceutical Sciences in Brno, 612 42 Brno, Czech Republic. pavelcikf@vfu.cz
Pavelcikova
Pamela
P
D000465:Algorithms; D018360:Crystallography, X-Ray / Q000379:methods; D030562:Databases, Protein; D008958:Models, Molecular; D009842:Oligopeptides / Q000737:chemistry*; D010446:Peptide Fragments / Q000737:chemistry*; D011487:Protein Conformation; D012984:Software
D009842:Oligopeptides; D010446:Peptide Fragments