title: Evidence for corticocortical connections between areas 7 and 17 in cerebral cortex of the cat.
abstract: This study provides the first evidence of direct corticocortical connections between areas 7 and 17 of the cat. Wheat germ agglutinin horseradish peroxidase (WGA-HRP) was administrated by micro-electrophoresis and micro-injection, respectively, into area 17 and area 7 in different hemispheres in eight cats. WGA-HRP labeled pyramidal neurons were observed primarily in layer 5 of areas 7 and 17 indicating that there are reciprocal connections between these areas. Optical imaging was used to guide WGA-HRP injections to single orientation columns in area 17. After such restricted injections labeled pyramidal cells were observed in layer 5 of area 7. These pyramidal cells were arranged as discontinuous patches extending across a broad region of area 7. These results suggest that feedback from area 7 to area 17 may arise from specific functional columns in area 7.
authors.affiliation: Vision Research Lab, Center for Brain Science Research, School of Life Sciences, Fudan University, Shanghai 200433, PR China.
authors.forename: Yanwen
authors.initials: Y
authors.lastname: Han
authors.forename: Xu
authors.initials: X
authors.lastname: Yang
authors.forename: Yuanxin
authors.initials: Y
authors.lastname: Chen
authors.forename: Tiande
authors.initials: T
authors.lastname: Shou
mesh_terms: D000818:Animals; D002415:Cats; D002540:Cerebral Cortex / Q000166:cytology*; D014795:Visual Pathways / Q000166:cytology*