title: The synthesis and herbicidal activity of 1-alkyl-3-(alpha-hydroxy-substituted benzylidene)pyrrolidine-2,4-diones.
abstract: In the search for better herbicides a series of 1-alkyl-3-(alpha-hydroxy-(un)substituted benzylidene)pyrrolidine-2,4-diones were prepared and their structure-activity relationships studied. All their structures have been confirmed by (1)H-NMR and elemental analysis. The preliminary bioassay results indicated that some of them have high herbicidal activity against annual dicotyledonous and monocotyledonous plants.
authors.affiliation: State Key Laboratory and Institute of Elemento-Organic Chemistry, Nankai University, Tianjin, 300071, PR China.
authors.forename: You-Quan
authors.initials: YQ
authors.lastname: Zhu
authors.forename: Chang-Sheng
authors.initials: CS
authors.lastname: Yao
authors.forename: Xiao-Mao
authors.initials: XM
authors.lastname: Zou
authors.forename: Fang-Zhong
authors.initials: FZ
authors.lastname: Hu
authors.forename: Bin
authors.initials: B
authors.lastname: Liu
authors.forename: Yong-Hong
authors.initials: YH
authors.lastname: Li
authors.forename: Hua-Zheng
authors.initials: HZ
authors.lastname: Yang
mesh_terms: D015111:4-Hydroxyphenylpyruvate Dioxygenase / Q000037:antagonists & inhibitors; D029688:Brassica napus / Q000187:drug effects; D004305:Dose-Response Relationship, Drug; D031747:Echinochloa / Q000187:drug effects; D004791:Enzyme Inhibitors / Q000138:chemical synthesis / Q000494:pharmacology; D006540:Herbicides / Q000138:chemical synthesis* / Q000494:pharmacology*; D008954:Models, Biological; D013329:Structure-Activity Relationship; D013379:Substrate Specificity; D013388:Succinimides / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*
chemical_list: D004791:Enzyme Inhibitors; D006540:Herbicides; D013388:Succinimides; D015111:4-Hydroxyphenylpyruvate Dioxygenase