title: The effects of different doses of remifentanil on intraocular pressure after tracheal intubation: a randomized, double-blind and prospective study.
abstract: We investigated the effects of alfentanil and different doses of remifentanil on intraocular pressure (IOP) and hemodynamic responses during laryngoscopy and endotracheal intubation in 60 patients. IOP values decreased significantly from 30 seconds before the intubation to 5 minutes after intubation measurements compared to baseline values in all the groups. However, a significant increase in IOP was recorded in the 0.5-microg remifentanil group after tracheal intubation.
authors.affiliation: Department of Anesthesiology, Cumhuriyet University School of Medicine, Sivas, 58140, Turkey. kaygusuzkenan@gmail.com
authors.forename: Kenan
authors.initials: K
authors.lastname: Kaygusuz
authors.forename: M Ilker
authors.initials: MI
authors.lastname: Toker
authors.forename: Iclal Ozdemir
authors.initials: IO
authors.lastname: Kol
authors.forename: Haydar
authors.initials: H
authors.lastname: Erdogan
authors.forename: Sinan
authors.initials: S
authors.lastname: Gursoy
authors.forename: Caner
authors.initials: C
authors.lastname: Mimaroglu
mesh_terms: D000328:Adult; D015760:Alfentanil / Q000627:therapeutic use; D000701:Analgesics, Opioid / Q000008:administration & dosage* / Q000627:therapeutic use; D004305:Dose-Response Relationship, Drug; D004311:Double-Blind Method; D005260:Female; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D007429:Intraocular Pressure / Q000187:drug effects*; D007442:Intubation, Intratracheal / Q000009:adverse effects*; D007828:Laryngoscopy / Q000009:adverse effects*; D008297:Male; D010880:Piperidines / Q000008:administration & dosage* / Q000627:therapeutic use; D017450:Receptors, Opioid, mu / Q000819:agonists; D000077208:Remifentanil; D013997:Time Factors
chemical_list: D000701:Analgesics, Opioid; D010880:Piperidines; D017450:Receptors, Opioid, mu; D015760:Alfentanil; D000077208:Remifentanil