Synthesis of fused polycycles from propargylic compounds with terminal alkynes via a palladium-catalyzed tandem C-H activation/biscyclization process.
Various benzo[b]fluorene and fluorene derivatives have been prepared from propargylic compounds with terminal alkynes through a novel palladium-catalyzed tandem biscyclization reaction. This reaction involved a sequence of carboannulation, coupling, C-H activation and C-C bond formation process. A plausible mechanism has been proposed that was consistent with the deuterium-labeling experiment.
Guo
Li-Na
LN
State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, China.
Duan
Xin-Hua
XH
Liu
Xue-Yuan
XY
Hu
Jie
J
Bi
Hai-Peng
HP
Liang
Yong-Min
YM