title: cAMP response element binding protein (CREB) overexpression CREB has been described as critical for leukemia progression.
abstract: CREB has been described as critical for leukemia progress. We investigated CREB expression in ALL and AML pediatric patients. CREB protein was significantly high (p<0.001) at diagnosis but not during remission. This study underlines the role of CREB in leukemia and suggests new insights into the transformation process.
authors.forename: Martina
authors.initials: M
authors.lastname: Pigazzi
authors.forename: Emanuela
authors.initials: E
authors.lastname: Ricotti
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Germano
authors.forename: Diego
authors.initials: D
authors.lastname: Faggian
authors.forename: Maurizio
authors.initials: M
authors.lastname: Aricò
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Basso
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D002877:Chromosomes, Human / Q000235:genetics; D017362:Cyclic AMP Response Element-Binding Protein / Q000378:metabolism*; D018450:Disease Progression; D006801:Humans; D007223:Infant; D007938:Leukemia / Q000235:genetics / Q000378:metabolism* / Q000473:pathology*; D008875:Middle Aged
chemical_list: D017362:Cyclic AMP Response Element-Binding Protein