title: Leishmanicidal activity of passifloricin A and derivatives.
abstract: Several natural and hemisyntetic passifloricins were assayed against Leishmania panamensis amastigotes. High leishmanicidal activity as well as toxicity was observed. The structure of a new compound is also reported.
authors.affiliation: Universidad de Antioquia, Instituto de Quimica, P. O. Box 1226, Medellín, Colombia.
authors.forename: Wilson
authors.initials: W
authors.lastname: Cardona
authors.forename: Winston
authors.initials: W
authors.lastname: Quiñones
authors.forename: Fernando
authors.initials: F
authors.lastname: Echeverri
mesh_terms: D000818:Animals; D000981:Antiprotozoal Agents / Q000737:chemistry / Q000494:pharmacology*; D006801:Humans; D007891:Leishmania / Q000187:drug effects*; D007928:Lethal Dose 50; D021261:Parasitic Sensitivity Tests; D011753:Pyrones / Q000737:chemistry / Q000494:pharmacology*; D020298:U937 Cells
chemical_list: D000981:Antiprotozoal Agents; D011753:Pyrones; C433046:passifloricin A