[The study of HPV prevalence in normal oral mucosa and oral squamous cell carcinoma].
Mucosal infection with high-risk human papiloma virus(HPV) types 16 and 18 is the cause of cervical cancer and might be a subset of oral squamous cell carcinoma (OSCC), yet the prevalence and type distribution of HPV in oral SCC remained unclear. We systematically reviewed published studies of OSCC biopsies, which were employed to detect and genotype HPV through different methods. The aim of this investigation is to carry out a bibliographic review on the prevalence of HPV in OSCC and normal oral mucosa. Supported by Key Project of National Natural Science Foundation of China (Grant No.30630065), Key Lab Project of Science and Technology Committee of Shanghai Municipality (Grant No.06DZ22026) and Shanghai Leading Academic Discipline Project (Grant No. Y0203).
Jiang
Qian
Q
Department of Oral and Maxillofacial Surgery, Shanghai Research Institute of Stomatology, Ninth People's Hospital, College of Stomatology, School of Medicine, Shanghai Jiao Tong University, China.
Zhang
Zhi-yuan
ZY
D002294:Carcinoma, Squamous Cell / Q000382:microbiology*; D002681:China; D004279:DNA, Viral; D005838:Genotype; D006801:Humans; D009061:Mouth Mucosa; D009062:Mouth Neoplasms / Q000382:microbiology*; D027383:Papillomaviridae / Q000235:genetics / Q000302:isolation & purification*; D030361:Papillomavirus Infections / Q000453:epidemiology*; D015995:Prevalence
D004279:DNA, Viral