title: Sequence-specific cleavage of human telomere DNA by G-quadruplex formation.
abstract: In the current study, we reported that oligonucleotide with EDTA-Fe at 5' end causes a sequence specific break in human telomeric DNA strand by G-quadruplex formation.
authors.affiliation: Research Center for Advanced Science and Technology, The University of Tokyo, 4-6-1 Komaba, Meguro-ku, Tokyo 153-8904, Japan.
authors.forename: Yan
authors.initials: Y
authors.lastname: Xu
authors.forename: Youhei
authors.initials: Y
authors.lastname: Hirohata
authors.forename: Makoto
authors.initials: M
authors.lastname: Komiyama
mesh_terms: D001483:Base Sequence; D004492:Edetic Acid / Q000737:chemistry; D054856:G-Quadruplexes; D006801:Humans; D015345:Oligonucleotide Probes / Q000737:chemistry*; D016615:Telomere / Q000737:chemistry*
chemical_list: D015345:Oligonucleotide Probes; D004492:Edetic Acid