title: Usefulness of serum albumin concentration for in-hospital risk stratification in frail, elderly patients with acute heart failure. Insights from a prospective, monocenter study.
abstract: The present study examined the usefulness of serum albumin concentration measured immediately after clinical stabilization for in-hospital risk stratification in 64 consecutive elderly, institutionalized patients with definite evidence of acute heart failure, of whom 17 died during their in-hospital stay. Serum albumin concentration was a powerful predictor of in-hospital death in this clinical setting (hazard ratio of 0.80 [0.71-0.89], p<0.001). A serum albumin concentration of <3 g/dl (median value) had a sensitivity of 94% and a specificity of 68% for the prediction of in-hospital mortality. Furthermore, this biomarker was able to provide incremental prognostic information over usual prognostic variables obtained at presentation such as age, systolic blood pressure and blood urea nitrogen.
authors.forename: Stephane
authors.initials: S
authors.lastname: Arques
authors.forename: Emmanuel
authors.initials: E
authors.lastname: Roux
authors.forename: Pascal
authors.initials: P
authors.lastname: Sbragia
authors.forename: Richard
authors.initials: R
authors.lastname: Gelisse
authors.forename: Bertrand
authors.initials: B
authors.lastname: Pieri
authors.forename: Pierre
authors.initials: P
authors.lastname: Ambrosi
mesh_terms: D000208:Acute Disease; D000369:Aged, 80 and over; D005260:Female; D016330:Frail Elderly; D006333:Heart Failure / Q000097:blood* / Q000175:diagnosis / Q000401:mortality; D017052:Hospital Mortality; D006760:Hospitalization; D006801:Humans; D008297:Male; D011446:Prospective Studies; D012307:Risk Factors; D012709:Serum Albumin / Q000378:metabolism*
chemical_list: D012709:Serum Albumin