title: Differences in breast cancer biological characteristics between ethnic groups in New Zealand.
abstract: OBJECTIVE
  To investigate differences in breast cancer biological characteristics between ethnic groups in Auckland, New Zealand.
  
  
  METHODS
  Prospective cohort study.
  
  
  METHODS
  Auckland Breast Cancer Study Group.
  
  
  METHODS
  All people diagnosed with breast cancer in the greater Auckland area between 2000 and 2005 who agreed to participate (1,577).
  
  
  METHODS
  Size, grade, lymph node status, estrogen receptor (ER), progesterone receptor (PR), lymphovascular invasion (LVI), grade allowing for size, all compared with ethnicity.
  
  
  RESULTS
  NZ Maori and Pacific Island participants had larger tumours (P < 0.0001), higher grade tumours (P < 0.0001) with more involved lymph nodes (P < 0.0001). When allowing for size, there was still an indication that NZ Maori people had higher grade tumours (P = 0.03). There was no difference in ER, PR and LVI between ethnic groups.
  
  
  CONCLUSIONS
  These data suggest differences in tumour biology related to ethnicity in the Auckland population and this has implications for breast cancer screening and management.
authors.affiliation: University of Auckland, Middlemore Hospital, Otahuhu, Auckland, 2105, New Zealand.
authors.forename: M K
authors.initials: MK
authors.lastname: Weston
authors.forename: D P
authors.initials: DP
authors.lastname: Moss
authors.forename: J
authors.initials: J
authors.lastname: Stewart
authors.forename: A G
authors.initials: AG
authors.lastname: Hill
mesh_terms: D005260:Female; D006801:Humans; D001943:Breast Neoplasms / Q000737:chemistry / Q000208:ethnology / Q000473:pathology; D008207:Lymphatic Metastasis; D009361:Neoplasm Invasiveness; D009367:Neoplasm Staging; D009520:New Zealand / Q000453:epidemiology; D011446:Prospective Studies; D011960:Receptors, Estrogen / Q000032:analysis; D011980:Receptors, Progesterone / Q000032:analysis; D012042:Registries; D044465:White People / Q000706:statistics & numerical data; D000095188:Pacific Island People / Q000706:statistics & numerical data
chemical_list: D011960:Receptors, Estrogen; D011980:Receptors, Progesterone