The genomic and metabolic diversity of Rickettsia.
Comparative genomics of Rickettsia and Orientia has revealed an exciting interplay between reductive evolutionary forces acting on metabolic genes in all species and proliferation of mobile genetic elements in some species. These contradictory evolutionary forces highlight the influence of chance, adaptation and host-cell exploitation during the evolution of intracellular bacteria.
Fuxelius
Hans-Henrik
HH
Department of Molecular Evolution, Evolutionary Biology Center, Uppsala University, Norbyvägen 18C, S-752 36 Uppsala, Sweden. hans.henrik.fuxelius@ebc.uu.se
Darby
Alistair
A
Min
Chan-Ki
CK
Cho
Nam-Hyuk
NH
Andersson
Siv G E
SG
D000818:Animals; D019143:Evolution, Molecular; D016680:Genome, Bacterial; D042822:Genomic Instability; D054884:Host-Pathogen Interactions; D006801:Humans; D012285:Orientia tsutsugamushi / Q000235:genetics / Q000472:pathogenicity; D012281:Rickettsia / Q000235:genetics* / Q000378:metabolism* / Q000472:pathogenicity; D012282:Rickettsia Infections / Q000235:genetics; D012283:Rickettsia prowazekii / Q000235:genetics / Q000472:pathogenicity; D014438:Typhus, Epidemic Louse-Borne / Q000382:microbiology