title: Septins: cellular and functional barriers of neuronal activity.
abstract: How conserved is sub-cellular compartmentalization across species and does it play a similar role? Here, two studies now demonstrate that buds in yeast and spines in mammalian neurons share many properties and suggest unexpected commonalities between simple and complex organisms.
authors.affiliation: Department of Biology, ETH Zürich, 8093 Zürich, Switzerland. yves.barral@bc.biol.ethz.ch
authors.forename: Yves
authors.initials: Y
authors.lastname: Barral
authors.forename: Isabelle M
authors.initials: IM
authors.lastname: Mansuy
mesh_terms: D000818:Animals; D003598:Cytoskeletal Proteins / Q000737:chemistry / Q000502:physiology*; D049229:Dendritic Spines / Q000201:enzymology / Q000502:physiology*; D020558:GTP Phosphohydrolases / Q000737:chemistry / Q000502:physiology*; D009474:Neurons / Q000166:cytology* / Q000201:enzymology* / Q000502:physiology; D029701:Saccharomyces cerevisiae Proteins / Q000737:chemistry / Q000502:physiology
chemical_list: D003598:Cytoskeletal Proteins; D029701:Saccharomyces cerevisiae Proteins; D020558:GTP Phosphohydrolases