Vascular endothelial growth factor level in the serum of diabetic patients with retinopathy.
We determined serum levels of vascular endothelial growth factor (VEGF) at different stages of diabetic retinopathy before laser photocoagulation in 65 patients (31 nonproliferative (Group 1) and 34 proliferative (Group 2)) and in healthy controls (Group 3). VEGF levels in all groups were different. There was a significant correlation between VEGF concentration and HbA1c levels. VEGF may be involved in the prediction of diabetic retinopathy and contributes to endothelial damage in diabetics.
Cavusoglu
A Celebiler
AC
Clinical Biochemistry, The Ministry of Health, Izmir Education & Research Hospital, Izmir, Turkey. aydan.cavusoglu@gmail.com
Bilgili
S
S
Alaluf
A
A
Doğan
A
A
Yilmaz
F
F
Aslanca
D
D
Karaca
B
B
Yüksel
B
B
Topaloglu
E
E
D000368:Aged; D001786:Blood Glucose / Q000032:analysis; D016022:Case-Control Studies; D002851:Chromatography, High Pressure Liquid; D003930:Diabetic Retinopathy / Q000097:blood*; D004797:Enzyme-Linked Immunosorbent Assay; D005215:Fasting / Q000097:blood; D005260:Female; D006442:Glycated Hemoglobin / Q000032:analysis; D006801:Humans; D008297:Male; D008875:Middle Aged; D009994:Osmolar Concentration; D011446:Prospective Studies; D042461:Vascular Endothelial Growth Factor A / Q000097:blood*
D001786:Blood Glucose; D006442:Glycated Hemoglobin; D042461:Vascular Endothelial Growth Factor A