title: Clathrin: an amazing multifunctional dreamcoat?
abstract: Internalization of cargo by clathrin-mediated endocytosis has been studied extensively. In this issue of Cell Host & Microbe, Cossart and colleagues report that a variety of pathogens induce the recruitment of clathrin and other endocytic proteins to sites of pathogen interaction with the cell surface. This recruitment is followed by actin rearrangements in the host cell necessary for the uptake or stable attachment of the pathogen at the cell surface.
authors.affiliation: Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720-3202, USA.
authors.forename: Barbara S
authors.initials: BS
authors.lastname: Pauly
authors.forename: David G
authors.initials: DG
authors.lastname: Drubin
mesh_terms: D000199:Actins / Q000378:metabolism; D000818:Animals; D001419:Bacteria / Q000472:pathogenicity; D001424:Bacterial Infections / Q000382:microbiology*; D018407:Bacterial Physiological Phenomena; D002462:Cell Membrane / Q000378:metabolism; D002966:Clathrin / Q000502:physiology*; D004705:Endocytosis; D006801:Humans
chemical_list: D000199:Actins; D002966:Clathrin