title: Epidermodysplasia verruciformis associated with isolated IgM deficiency.
abstract: A 20 year-old man presented to our clinic with multiple warts on both hands and tumoral lesions on his face but otherwise healthy. On dermatological examination, numerous brown-black papular lesions, changing from 2 to 5 cm in diameter were found on his face along with multiple, flesh-coloured, flat-topped papules on the dorsa of his hands. A tumoral lesion, approximately 3 cm in diameter on the right side of his forehead and desquamated erythematous macules were also observed on the trunk. Laboratory investigations showed that serum immunoglobulin M (IgM) level was decreased. The histopathological examination of verrucous lesions on the hands was consistent with epidermodysplasia verruciformis and the histopathological diagnosis of the tumoral lesion was squamous cell carcinoma.
authors.affiliation: Department of Dermatology, Ankara Numune Education and Research Hospital, Ankara, Turkey.
authors.forename: Ulker
authors.initials: U
authors.lastname: Gul
authors.forename: Secil
authors.initials: S
authors.lastname: Soylu
authors.forename: Rana
authors.initials: R
authors.lastname: Yavuzer
mesh_terms: D000328:Adult; D002294:Carcinoma, Squamous Cell / Q000473:pathology; D004819:Epidermodysplasia Verruciformis / Q000473:pathology*; D006801:Humans; D007075:Immunoglobulin M / Q000172:deficiency*; D008297:Male; D012878:Skin Neoplasms / Q000473:pathology
chemical_list: D007075:Immunoglobulin M