[Influence of modified food starches on composition and phagocytic activity of peritoneal cells].
Modified maize starches having differences in the number of crosscut lacings in the structure, and in the abilities to be gelatinized in the cold water were used: native maize starch "Novation 4600", acetylated adipat di-starch of the cold swelling "Prejeflo CH 20", acetylated adipat di-starch of the cold swelling "Prejeflo CH 40", acetylated adipat di-starch of the hot swelling "Clearam CH 2020". All investigated starches possessed the ability to activate neutrophils and to increase their phagocytosis 2 h after i.p. administration. Four days after i.p. injection, starches and their hydrolyzet starch products were shown to stimulate the neutrophils and lymphocytes into peritoneal cavity. Starch digest products have the more stimulated capacities compared with native compounds that indicates the possible immune activity of starch carbohydrate chain fragments.
Martynova
E A
EA
Sokolov
A I
AI
Kulikova
O S
OS
Gapparov
M M
MM
D000818:Animals; D002465:Cell Movement / Q000187:drug effects* / Q000276:immunology; D008214:Lymphocytes / Q000166:cytology / Q000276:immunology / Q000378:metabolism*; D008297:Male; D051379:Mice; D008811:Mice, Inbred DBA; D018375:Neutrophil Activation / Q000187:drug effects* / Q000276:immunology; D009504:Neutrophils / Q000166:cytology / Q000276:immunology / Q000378:metabolism*; D010529:Peritoneal Cavity / Q000166:cytology / Q000502:physiology; D010587:Phagocytosis / Q000187:drug effects*; D013213:Starch / Q000276:immunology / Q000494:pharmacology*
D013213:Starch