title: Reassessment of the cutoff values of waist circumference and visceral fat area for identifying Japanese subjects at risk for the metabolic syndrome.
abstract: In the new world-wide criteria for metabolic syndrome (MetS) by the International Diabetes Federation (IDF) in 2006, the Japanese is the only ethnicity in which the recommended waist circumference (WC) cutoff value is higher in women (>or=90cm) than in men (>or=85cm), and its validity appears to be controversial. We investigated the optimal cutoff points for the diagnosis of central obesity in Japanese men and women, using the receiver operating characteristic (ROC) curve analysis for both of WC and visceral fat area (VFA) in 1870 middle-aged Japanese. VFA was superior to WC and Body mass index (BMI) for discriminating the subjects with two or more nonadipose components of MetS. The optimal cutoff points of VFA and WC were 132.6cm(2) and 89.8cm for men and 91.5cm(2) and 82.3cm for women. The stratifications of MetS components more than 1.0 in average occurred more steeply by the accumulation of VFA in women than in men. In conclusion, setting the cutoff points of WC and VFA lower values in women than in men for the definition of central obesity is needed to identify the subjects with MetS in Japanese, as in other Asian populations.
authors.affiliation: Department of Internal Medicine, Hokuriku Central Hospital of Japan Mutual Aid Association of Public School Teachers, 123 Nodera, Oyabe, Toyama 932-8503, Japan. ririoka@goo.jp
authors.forename: Rie
authors.initials: R
authors.lastname: Oka
authors.forename: Junji
authors.initials: J
authors.lastname: Kobayashi
authors.forename: Kunimasa
authors.initials: K
authors.lastname: Yagi
authors.forename: Hideji
authors.initials: H
authors.lastname: Tanii
authors.forename: Susumu
authors.initials: S
authors.lastname: Miyamoto
authors.forename: Akimichi
authors.initials: A
authors.lastname: Asano
authors.forename: Tomomi
authors.initials: T
authors.lastname: Hagishita
authors.forename: Mika
authors.initials: M
authors.lastname: Mori
authors.forename: Tadashi
authors.initials: T
authors.lastname: Moriuchi
authors.forename: Makoto
authors.initials: M
authors.lastname: Kobayashi
authors.forename: Shouji
authors.initials: S
authors.lastname: Katsuda
authors.forename: Masa-aki
authors.initials: MA
authors.lastname: Kawashiri
authors.forename: Atsushi
authors.initials: A
authors.lastname: Nohara
authors.forename: Yoshiyu
authors.initials: Y
authors.lastname: Takeda
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Mabuchi
authors.forename: Masakazu
authors.initials: M
authors.lastname: Yamagishi
mesh_terms: D000328:Adult; D044466:Asian People; D015992:Body Mass Index; D005260:Female; D006801:Humans; D050152:Intra-Abdominal Fat / Q000378:metabolism*; D007564:Japan; D008297:Male; D024821:Metabolic Syndrome / Q000175:diagnosis* / Q000208:ethnology / Q000209:etiology; D008875:Middle Aged; D009765:Obesity / Q000150:complications / Q000378:metabolism*; D012307:Risk Factors; D012737:Sex Factors; D049629:Waist-Hip Ratio