title: Fragrance material review on 4-(1,2-epoxy-2,6,6-trimethylcyclohexyl)-3-buten-2-one.
abstract: A toxicologic and dermatologic review of 4-(1,2-epoxy-2,6,6-trimethylcyclohexyl)-3-buten-2-one when used as a fragrance ingredient is presented.
authors.affiliation: Research Institute for Fragrance Materials, Inc., 50 Tice Boulevard, Woodcliff Lake, NJ 07677, USA.
authors.forename: J
authors.initials: J
authors.lastname: Lalko
authors.forename: A
authors.initials: A
authors.lastname: Lapczynski
authors.forename: D
authors.initials: D
authors.lastname: McGinty
authors.forename: S
authors.initials: S
authors.lastname: Bhatia
authors.forename: C S
authors.initials: CS
authors.lastname: Letizia
authors.forename: A M
authors.initials: AM
authors.lastname: Api
mesh_terms: D002073:Butanes / Q000145:classification / Q000493:pharmacokinetics / Q000633:toxicity*; D003257:Consumer Product Safety; D003510:Cyclohexanes / Q000145:classification / Q000493:pharmacokinetics / Q000633:toxicity*; D004305:Dose-Response Relationship, Drug; D006801:Humans; D009152:Mutagenicity Tests; D009153:Mutagens / Q000145:classification / Q000493:pharmacokinetics / Q000633:toxicity*; D010476:Perfume / Q000145:classification / Q000493:pharmacokinetics / Q000633:toxicity*; D018570:Risk Assessment; D012486:Salmonella typhimurium / Q000187:drug effects / Q000235:genetics; D012867:Skin / Q000187:drug effects / Q000378:metabolism; D012869:Skin Absorption
chemical_list: C526429:4-(1,2-epoxy-2,6,6-trimethylcyclohexyl)-3-buten-2-one; D002073:Butanes; D003510:Cyclohexanes; D009153:Mutagens; D010476:Perfume