title: Recurrent juvenile granulosa cell tumor of the ovary managed by palliative radiotherapy.
abstract: Prognosis in the few patients with advanced-stage juvenile granulosa cell tumor (JGCT) of the ovary has traditionally been unfavorable. We report a recurrent JGCT patient managed by palliative radiotherapy. A 37-year-old woman with recurrent JGCT received a combination of paclitaxel-carboplatin chemotherapy and then single-agent docetaxel, but her disease progressed with multiple abdominal masses and ascites. We chose palliative radiation therapy to relieve her complaints. Whole-abdominal external beam radiotherapy with pelvic boost was delivered. She tolerated the treatment well. After the completion of radiotherapy, ultrasonography showed shrinkage of the tumor, and the ascites disappeared. We should consider using radiation therapy in a palliative setting for such patients with recurrent JGCT suffering from abdominal complaints.
authors.affiliation: Department of Obstetrics and Gynecology, Faculty of Medicine, University of the Ryukyus, Okinawa, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Hirakawa
authors.forename: Y
authors.initials: Y
authors.lastname: Nagai
authors.forename: C
authors.initials: C
authors.lastname: Yagi
authors.forename: T
authors.initials: T
authors.lastname: Nashiro
authors.forename: M
authors.initials: M
authors.lastname: Inamine
authors.forename: Y
authors.initials: Y
authors.lastname: Aoki
mesh_terms: D000328:Adult; D001706:Biopsy; D005260:Female; D006106:Granulosa Cell Tumor / Q000145:classification / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery; D006801:Humans; D009364:Neoplasm Recurrence, Local / Q000145:classification / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery; D010166:Palliative Care; D014057:Tomography, X-Ray Computed