title: A boundary-representation method for designing whole-body radiation dosimetry models: pregnant females at the ends of three gestational periods--RPI-P3, -P6 and -P9.
abstract: Fetuses are extremely radiosensitive and the protection of pregnant females against ionizing radiation is of particular interest in many health and medical physics applications. Existing models of pregnant females relied on simplified anatomical shapes or partial-body images of low resolutions. This paper reviews two general types of solid geometry modeling: constructive solid geometry (CSG) and boundary representation (BREP). It presents in detail a project to adopt the BREP modeling approach to systematically design whole-body radiation dosimetry models: a pregnant female and her fetus at the ends of three gestational periods of 3, 6 and 9 months. Based on previously published CT images of a 7-month pregnant female, the VIP-Man model and mesh organ models, this new set of pregnant female models was constructed using 3D surface modeling technologies instead of voxels. The organ masses were adjusted to agree with the reference data provided by the International Commission on Radiological Protection (ICRP) and previously published papers within 0.5%. The models were then voxelized for the purpose of performing dose calculations in identically implemented EGS4 and MCNPX Monte Carlo codes. The agreements of the fetal doses obtained from these two codes for this set of models were found to be within 2% for the majority of the external photon irradiation geometries of AP, PA, LAT, ROT and ISO at various energies. It is concluded that the so-called RPI-P3, RPI-P6 and RPI-P9 models have been reliably defined for Monte Carlo calculations. The paper also discusses the needs for future research and the possibility for the BREP method to become a major tool in the anatomical modeling for radiation dosimetry.
authors.affiliation: Nuclear Engineering and Engineering Physics Program, Rensselaer Polytechnic Institute, 110 Eighth St, Troy, NY 12180, USA. xug2@rpi.edu
authors.forename: X George
authors.initials: XG
authors.lastname: Xu
authors.forename: Valery
authors.initials: V
authors.lastname: Taranenko
authors.forename: Juying
authors.initials: J
authors.lastname: Zhang
authors.forename: Chengyu
authors.initials: C
authors.lastname: Shi
mesh_terms: D000465:Algorithms; D003198:Computer Simulation; D005260:Female; D005865:Gestational Age; D006801:Humans; D008954:Models, Biological; D011247:Pregnancy / Q000502:physiology*; D011874:Radiometry / Q000379:methods*; D011879:Radiotherapy Dosage; D011880:Radiotherapy Planning, Computer-Assisted / Q000379:methods*; D014916:Whole-Body Irradiation / Q000379:methods*