Stem cells in experimental chronic hepatitis.
We studied the state of the pools of mesenchymal precursor cells in the bone marrow and peripheral blood and the dynamics of regional precursor cells in the liver in experimental chronic hepatitis. We showed that bone marrow mesenchymal stem cells are involved in liver regeneration in its chronic disease. Our results suggest that these mechanisms are insufficient for the recovery of liver tissue.
Dygai
A M
AM
Institute of Pharmacology, Tomsk Research Center, Russian Academy of Medical Sciences.
Zhdanov
V V
VV
Epstein
O I
OI
Zyuz'kov
G N
GN
Sergeyeva
S A
SA
Vetoshkina
T V
TV
Fomina
T I
TI
Gur'yantseva
A
A
Stavrova
L A
LA
Sotnikova
N V
NV
Gol'dberg
E D
ED
D000818:Animals; D001854:Bone Marrow Cells / Q000473:pathology*; D002252:Carbon Tetrachloride Poisoning / Q000473:pathology; D056486:Chemical and Drug Induced Liver Injury / Q000473:pathology*; D005260:Female; D006521:Hepatitis, Chronic / Q000473:pathology*; D008099:Liver / Q000473:pathology; D008297:Male; D059630:Mesenchymal Stem Cells / Q000473:pathology*; D051379:Mice; D051381:Rats