Parallel processable light-driven DNA logic gate.
Here, we report the construction of a photochemical DNA logic circuit made entirely of DNA and implemented with sequence-specific photo-cleavage (SSPC) of photocrosslinking sites enclosed in the gate strand. As example, we demonstrate the performance of logic operations including NOT, AND, OR, and full-adder using a SSPC reaction.
Ogasawara
Shinzi
S
Bioengineering Laboratory, RIKEN, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan.
Ammi
Takehiro
T
Fujimoto
Kenzo
K
D001483:Base Sequence; D002227:Carbazoles / Q000737:chemistry; D039301:Computers, Molecular; D004247:DNA / Q000737:chemistry; D008969:Molecular Sequence Data; D009838:Oligodeoxyribonucleotides / Q000737:chemistry* / Q000528:radiation effects; D010777:Photochemistry
D002227:Carbazoles; D009838:Oligodeoxyribonucleotides; D004247:DNA