Magnetic nanoparticle-supported proline as a recyclable and recoverable ligand for the CuI catalyzed arylation of nitrogen nucleophiles.
Magnetic nanoparticle-supported proline ligand was prepared and used for the CuI catalyzed Ullmann-type coupling reactions of aryl/heteroaryl bromides with various nitrogen heterocycles to form the corresponding N-aryl products in good to excellent yields; furthermore, this magnetic nanoparticle-supported proline ligand could be readily separated using an external magnet and reused without significant loss of activity.
Chouhan
Gagan
G
Centre for Catalysis Research and Innovation, Department of Chemistry, University of Ottawa, 10 Marie Curie, Ottawa, Ontario, Canada K1N 6N5.
Wang
Dashan
D
Alper
Howard
H
D000098:Acetophenones / Q000737:chemistry; D001386:Azides / Q000737:chemistry; D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D007093:Imidazoles / Q000737:chemistry; D007454:Iodides / Q000737:chemistry*; D008024:Ligands; D008280:Magnetics; D046529:Microscopy, Electron, Transmission; D015394:Molecular Structure; D053758:Nanoparticles / Q000737:chemistry* / Q000648:ultrastructure; D009584:Nitrogen / Q000737:chemistry*; D011392:Proline / Q000737:chemistry*
D000098:Acetophenones; D001386:Azides; D007093:Imidazoles; D007454:Iodides; D008024:Ligands; D003300:Copper; C073870:cuprous iodide; C029899:imidazole; C020232:4-bromoacetophenone; D011392:Proline; D009584:Nitrogen