title: Structural and functional changes in epitheliocytes of collecting tubes in renal papilla of Brattleboro rats treated with vasopressin.
abstract: The functional response of the kidney to desmopressin and morphological changes in epitheliocytes of collecting tubes were studied on homozygotic Brattleboro rats. Redistribution of beta-glucuronidase fractions and increase in the number of osmiophilic granules reflecting increased production of vasopressin-dependent proteins and hyaluronate hydrolase exocytosis were typical structural correlates of the effect of vasopressin.
authors.affiliation: Department of Physiology, Novosibirsk State University.
authors.forename: L N
authors.initials: LN
authors.lastname: Ivanova
authors.forename: V A
authors.initials: VA
authors.lastname: Lavrinenko
authors.forename: L V
authors.initials: LV
authors.lastname: Shestopalova
authors.forename: S M
authors.initials: SM
authors.lastname: Korotkova
mesh_terms: D000818:Animals; D003894:Deamino Arginine Vasopressin / Q000494:pharmacology; D005966:Glucuronidase / Q000378:metabolism; D006651:Histocytochemistry; D006720:Homozygote; D007679:Kidney Medulla / Q000166:cytology* / Q000502:physiology / Q000648:ultrastructure; D007685:Kidney Tubules, Collecting / Q000166:cytology* / Q000502:physiology / Q000648:ultrastructure; D009994:Osmolar Concentration; D051381:Rats; D011910:Rats, Brattleboro; D017483:Receptors, Vasopressin / Q000819:agonists; D014563:Urodynamics; D019459:Urothelium / Q000166:cytology* / Q000502:physiology / Q000648:ultrastructure; D014667:Vasopressins / Q000235:genetics / Q000502:physiology*
chemical_list: D017483:Receptors, Vasopressin; D014667:Vasopressins; D005966:Glucuronidase; D003894:Deamino Arginine Vasopressin