"Non-toxic" cyclic peptides induce lysis of cyanobacteria-an effective cell population density control mechanism in cyanobacterial blooms.
The presence of planktopeptin BL1125, anabaenopeptin B and anabaenopeptin F, two types of "non-toxic" cyclic peptide produced in bloom forming cyanobacteria, can provoke lysis of different non-axenic Microcystis aeruginosa cell lines via the induction of virus-like particles. The resulting particles are also able to infect the axenic M. aeruginosa cell line without lytic effects. Nevertheless, the presence of "non-toxic" cyclic peptides of cyanobacterial origin can induce lysis of these previously infected cells. This effect implies that a possible role of these peptides in the natural environment is the control of cyanobacterial population density. Lysogenic cyanobacteria can consequently act as hot-spots that, in the presence of cyanobacterial cyclic peptides, release numerous infectious particles. The process can be self-augmented with the simultaneous release of additional cyclic peptides from the producing lysogens, starting a forest fire effect that ends in collapse of cyanobacterial blooms.
Sedmak
B
B
Department of Genetic Toxicology and Cancer Biology, National Institute of Biology Ljubljana, Vecna pot 111, 1000, Ljubljana, Slovenia. bojan.sedmak@nib.si
Carmeli
S
S
Elersek
Tina
T
D001433:Bacteriolysis; D001435:Bacteriophages / Q000502:physiology*; D015169:Colony Count, Microbial; D005068:Eutrophication; D008242:Lysogeny; D046931:Microcystis / Q000187:drug effects / Q000502:physiology / Q000821:virology; D010456:Peptides, Cyclic / Q000494:pharmacology*; D011156:Population Density
D010456:Peptides, Cyclic; C496665:anabaenopeptin B; C436355:anabaenopeptin F