Myocardial perfusion assessment by use of system identification method in a one-compartment model.
Cardiovascular magnetic resonance has been shown to provide high data quality for myocardial perfusion assessment. However, to analyze the perfusion data, some signal processing and modeling is needed to correct for motion related artifacts and limited spatial resolution. This study describes a method based on system identification, allowing, after a first step of image registration, to integrate and correct the partial volume effect in the myocardium perfusion quantification. This method is then applied to patients with coronary artery disease or hypertrophic obstructive cardiomyopathy.
Kocher
M
M
Biomedical Imaging Group, EPFL, Station 17, 1015 Lausanne, Switzerland. michel.kocher@hesge.ch
Daire
J L
JL
Thevenaz
P
P
Schindler
T
T
Keller
P F
PF
Didier
D
D
Vallee
J P
JP
D000368:Aged; D002312:Cardiomyopathy, Hypertrophic / Q000473:pathology / Q000503:physiopathology*; D003324:Coronary Artery Disease / Q000000981:diagnostic imaging / Q000503:physiopathology*; D003326:Coronary Circulation; D005260:Female; D006321:Heart / Q000503:physiopathology*; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D008955:Models, Cardiovascular; D009203:Myocardial Infarction / Q000473:pathology / Q000503:physiopathology; D010477:Perfusion; D011859:Radiography