Simple and efficient synthesis of 2,7-difunctionalized-1,8-naphthyridines.
The syntheses in good yields of some new difunctionalized 1,8-naphthyridines 4, 6, 8 and 9 and a novel triethylene glycol ether-linked dinaphthyridine, 10a, along with the mononaphthyridine-linked ether alcohol 10b are described. An improved and milder method for the synthesis of 2,7-diamino-1,8-naphthyridine (14) is also reported.
Goswami
Shyamaprosad
S
Department of Chemistry, Bengal Engineering and Science University, Shibpur, West Bengal, India. spgoswamical@yahoo.com
Mukherjee
Reshmi
R
Mukherjee
Rakhi
R
Jana
Subrata
S
Maity
Annada C
AC
Adak
Avijit Kumar
AK
D009287:Naphthyridines / Q000138:chemical synthesis* / Q000737:chemistry; D011092:Polyethylene Glycols / Q000737:chemistry; D013696:Temperature
D009287:Naphthyridines; C028914:triethylene glycol; D011092:Polyethylene Glycols