title: Primitive neuroectodermal tumor of the lung with pericardial extension: a case report.
abstract: A 16-year-old student presented with a 4-week history of progressive shortness of breath, loss of appetite, and occasional blood-tinged sputum. The chest X-ray revealed massive right-sided pleural effusion with cardiomegaly. An echocardiogram revealed a large pericardial mass with massive pericardial effusion. Subsequent computed tomography of the thorax revealed a large heterogeneous mass in the right lung with extension into the pericardium. Lung biopsy revealed primitive neuroectodermal tumor (PNET) with small round blue cells, Homer-Wright rosettes, and CD99 positivity. We discuss pericardial metastases of PNET and its implication in this patient.
authors.affiliation: Department of Internal Medicine, International Islamic University Malaysia, Jalan Hospital Campus, Kuantan, Pahang Darul Makmur 25150, Malaysia. risman1973@hotmail.com <risman1973@hotmail.com>
authors.forename: Azarisman
authors.initials: A
authors.lastname: Shah Mohd Shah
authors.forename: Zamri
authors.initials: Z
authors.lastname: Mohamed
authors.forename: Aszrin
authors.initials: A
authors.lastname: Abdullah
authors.forename: Puteri Melor
authors.initials: PM
authors.lastname: Abdul Malek
authors.forename: Noorfaizan
authors.initials: N
authors.lastname: Saidin
authors.forename: Oteh
authors.initials: O
authors.lastname: Maskon
mesh_terms: D000071443:12E7 Antigen; D000293:Adolescent; D015703:Antigens, CD / Q000032:analysis; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D015815:Cell Adhesion Molecules / Q000032:analysis; D004452:Echocardiography; D006338:Heart Neoplasms / Q000150:complications / Q000188:drug therapy / Q000276:immunology / Q000473:pathology*; D006801:Humans; D008175:Lung Neoplasms / Q000188:drug therapy / Q000276:immunology / Q000473:pathology*; D008297:Male; D009361:Neoplasm Invasiveness; D018241:Neuroectodermal Tumors, Primitive, Peripheral / Q000150:complications / Q000188:drug therapy / Q000276:immunology / Q000473:pathology*; D010490:Pericardial Effusion / Q000209:etiology* / Q000473:pathology; D010496:Pericardium / Q000276:immunology / Q000473:pathology*; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D000071443:12E7 Antigen; D015703:Antigens, CD; C061828:CD99 protein, human; D015815:Cell Adhesion Molecules