title: Effect of non-surgical periodontal therapy on patients with type 2 diabetes mellitus.
abstract: The AIM of this study was to evaluate the effect of non-surgical therapy on clinical variables and glycemic control on type 2 diabetics with chronic periodontitis.
  
  
  METHODS
  Forty six type 2 diabetics with chronic periodontitis were randomized into two groups (group A and group B). Treatment included scaling and root planning for group A plus systematic use of doxycycline in both groups. Assessment was made prior to and 16 weeks following the therapy.
  
  
  RESULTS
  Analysis of data showed that both groups had clinical and glycated hemoglobin (HbAlc) improvement after the treatment. Group A had a statistically significant reduction of plaque index and bleeding on probing scores compared with controls (P < 0.05) at 16 weeks.
  
  
  CONCLUSIONS
  These results suggest that non-surgical therapy is of value in maintaining periodontal health and may be beneficial in reducing blood glucose level in type 2 diabetics with chronic periodontitis.
authors.affiliation: Department of Periodontal and Oral Diseases, Guanghua College of Stomatology, Sun Yat-Sen Univesity, Guangzhou, China.
authors.forename: Fu
authors.initials: F
authors.lastname: Yun
authors.forename: Elena I
authors.initials: EI
authors.lastname: Firkova
authors.forename: Lin
authors.initials: L
authors.lastname: Jun-Qi
authors.forename: Hong
authors.initials: H
authors.lastname: Xun
mesh_terms: D001786:Blood Glucose / Q000378:metabolism; D016022:Case-Control Studies; D003924:Diabetes Mellitus, Type 2 / Q000097:blood / Q000150:complications*; D005260:Female; D006442:Glycated Hemoglobin / Q000378:metabolism; D006801:Humans; D008297:Male; D008875:Middle Aged; D010518:Periodontitis / Q000150:complications* / Q000628:therapy*
chemical_list: D001786:Blood Glucose; D006442:Glycated Hemoglobin