title: [A case of advanced breast cancer leading to DIC after chemotherapy].
abstract: We reported a case of DIC who was administered FEC90 (5-FU 1,000 mg/body, epirubicin 170 mg/body, cyclophosphamide 1,000 mg/body) for advanced breast cancer. A 55-year-old woman was referred to our hospital with lumbago. There was a huge tumor in her left breast (10x10 cm) and bone scintigraphy showed multiple bone metastasis, so she was treated with FEC90. Before the third course, DIC occurred. The patient was then treated with FOY and heparin, and the DIC was resolved. We think the DIC of this case was related with tumor lysis syndrome. Febrile neutropenia has been occasionally emphasized during chemotherapy, but due care must be taken for lymphocyte depletion during treatment.
authors.affiliation: Dept. of Surgery, Himeji Red Cross Hospital.
authors.forename: Shinji
authors.initials: S
authors.lastname: Ishizuka
authors.forename: Tatsuya
authors.initials: T
authors.lastname: Morikawa
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Yoshida
authors.forename: Tetsuji
authors.initials: T
authors.lastname: Nobuhisa
authors.forename: Yoshikatsu
authors.initials: Y
authors.lastname: Endo
authors.forename: Takanori
authors.initials: T
authors.lastname: Watanabe
authors.forename: Yuusuke
authors.initials: Y
authors.lastname: Matsumoto
authors.forename: Yoshinori
authors.initials: Y
authors.lastname: Doi
authors.forename: Takatoshi
authors.initials: T
authors.lastname: Yamada
authors.forename: Kyouhei
authors.initials: K
authors.lastname: Kai
authors.forename: Akira
authors.initials: A
authors.lastname: Nakashima
authors.forename: Itaru
authors.initials: I
authors.lastname: Nagahiro
authors.forename: Shizo
authors.initials: S
authors.lastname: Sato
authors.forename: Akira
authors.initials: A
authors.lastname: Nakashima
authors.forename: Akira
authors.initials: A
authors.lastname: Nabeyama
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage / Q000627:therapeutic use*; D001859:Bone Neoplasms / Q000556:secondary; D001943:Breast Neoplasms / Q000150:complications* / Q000188:drug therapy* / Q000473:pathology; D003520:Cyclophosphamide / Q000008:administration & dosage; D004211:Disseminated Intravascular Coagulation / Q000209:etiology*; D004334:Drug Administration Schedule; D015251:Epirubicin / Q000008:administration & dosage; D005260:Female; D005472:Fluorouracil / Q000008:administration & dosage; D006801:Humans; D008875:Middle Aged; D009367:Neoplasm Staging
chemical_list: D015251:Epirubicin; D003520:Cyclophosphamide; D005472:Fluorouracil