Synthesis of cyclophellitol utilizing a palladium chloride mediated-Ferrier-II rearrangement.
Cyclophellitol and its C3-epimer have been synthesized from5-enoglucopyranoside and 5-enomannopyranoside, respectively. The carbocyclic skeletonwas constructed through a Ferrier-II reaction meditated by PdCl2.
Takahashi
Hideyo
H
Faculty of Pharmaceutical Sciences, Teikyo University, Sagamiko, Kanagawa 199-0195, Japan.
Ikegami
Shiro
S
D003511:Cyclohexanols / Q000138:chemical synthesis* / Q000737:chemistry; D008956:Models, Chemical; D008968:Molecular Conformation; D010165:Palladium / Q000737:chemistry*; D013696:Temperature
D003511:Cyclohexanols; C063285:cyclophellitol; D010165:Palladium; C008756:palladium chloride