A direct route to 6,6'-disubstituted-2,2'-bipyridines by double Diels-Alder/retro Diels-Alder reaction of 5,5'-bi-1,2,4-triazines.
Inverse electron demand Diels-Alder reaction of functionalized 5,5'-bi-1,2,4- triazines with bicyclo[2.2.1]hepta-2,5-diene in boiling p-cymene leads to a range of 6,6'- disubstituted-2,2'-bipyridines in good yield.
Branowska
Danuta
D
Institute of Chemistry, University of Podlasie, PL-08-110 Siedlce, Poland. dankab@ap.siedlce.pl
D002625:Chemistry, Organic / Q000379:methods*; D008954:Models, Biological; D008956:Models, Chemical; D011725:Pyridines / Q000138:chemical synthesis* / Q000737:chemistry*; D014227:Triazines / Q000737:chemistry*
D011725:Pyridines; D014227:Triazines