title: Markers of inflammation as determinants of mortality in intensive care unit patients.
abstract: In this study, the investigators explored the relationship between mortality rate and serum levels of C-reactive protein (CRP), erythrocyte sedimentation ratio (ESR), albumin, and hemoglobin, leukocyte, and platelet counts of patients at the time of first admission to the intensive care unit (ICU). A total of 123 patients were admitted to 2 different ICUs. In the emergency departments, serum levels of CRP, ESR, and albumin and hematologic parameters of 81 patients who died and 42 patients who survived were compared. A Student t test and the chi2 test were used for statistical analyses. Mean CRP and ESR levels and leukocyte counts were higher in nonsurvivor than in survivor groups (P<.001 for all). Additionally, serum CRP and ESR elevations and leukocyte counts were determined to be individually related to mortality (P<.001, P<.05, and P<.05, respectively). The investigators concluded that initial serum levels of CRP and ESR and leukocyte counts can be used as determinants of mortality in ICU patients.
authors.affiliation: Department of Emergency Medicine, Mustafa Kemal University, Hatay, Turkey. guvenkuvandik@yahoo.com
authors.forename: Guven
authors.initials: G
authors.lastname: Kuvandik
authors.forename: Edip
authors.initials: E
authors.lastname: Ucar
authors.forename: Ali
authors.initials: A
authors.lastname: Borazan
authors.forename: Selim
authors.initials: S
authors.lastname: Aydemir
authors.forename: Sevil
authors.initials: S
authors.lastname: Ilikhan
authors.forename: Nedred
authors.initials: N
authors.lastname: Sekitmez
authors.forename: Mehmet
authors.initials: M
authors.lastname: Duru
authors.forename: Burcin
authors.initials: B
authors.lastname: Ozer
authors.forename: Hasan
authors.initials: H
authors.lastname: Kaya
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D015415:Biomarkers / Q000097:blood; D005260:Female; D017052:Hospital Mortality; D006801:Humans; D007249:Inflammation / Q000097:blood / Q000175:diagnosis*; D007362:Intensive Care Units; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D012189:Retrospective Studies
chemical_list: D015415:Biomarkers