title: Syntheses of quinazoline-2,4-dione alkaloids and analogues from Mexican Zanthoxylum species.
abstract: Quinazolinone and quinazolinedione derivatives are of considerable interest due to their wide array of pharmacological properties. In this paper we report the synthesis of ten quinazolinediones. The previous isolation of two of these compounds, namely 1-methyl-3-(2'-phenylethyl)-1H,3H-quinazoline-2,4-dione and 1-methyl-3-[2'-(4'- methoxyphenyl)ethyl]-lH,3H-quinazoline-2,4-dione, from the seed husks of Mexican Zanthoxylum species has been reported.
authors.affiliation: Centro de Graduados e Investigación, Instituto Tecnológico de Tijuana, Apartado Postal 1166. 22000, Tijuana, BC México. irivero@tectijuana.mx
authors.forename: I A
authors.initials: IA
authors.lastname: Rivero
authors.forename: K
authors.initials: K
authors.lastname: Espinoza
authors.forename: R
authors.initials: R
authors.lastname: Somanathan
mesh_terms: D000470:Alkaloids / Q000138:chemical synthesis* / Q000737:chemistry; D008800:Mexico; D011799:Quinazolines / Q000138:chemical synthesis* / Q000737:chemistry; D032106:Zanthoxylum / Q000737:chemistry*
chemical_list: D000470:Alkaloids; D011799:Quinazolines; C081989:2,4(1H,3H)-quinazolinedione