title: Modulation of cardiac autonomic balance with adjuvant yoga therapy in patients with refractory epilepsy.
abstract: The practice of yoga regulates body physiology through control of posture, breathing, and meditation. Effects of yoga on autonomic functions of patients with refractory epilepsy, as quantified by standardized autonomic function tests (AFTs), were determined. The yoga group (n=18) received supervised training in yoga, and the exercise group (n=16) practiced simple routine exercises. AFTs were repeated after 10 weeks of daily sessions. Data were compared with those of healthy volunteers (n=142). The yoga group showed significant improvement in parasympathetic parameters and a decrease in seizure frequency scores. There was no improvement in blood pressure parameters in either group. Two patients in the yoga group achieved normal autonomic functions at the end of 10 weeks of therapy, whereas there were no changes in the exercise group. The data suggest that yoga may have a role as an adjuvant therapy in the management of autonomic dysfunction in patients with refractory epilepsy.
authors.affiliation: Department of Neurophysiology, National Institute of Mental Health and Neurosciences, Bangalore, India.
authors.forename: T N
authors.initials: TN
authors.lastname: Sathyaprabha
authors.forename: P
authors.initials: P
authors.lastname: Satishchandra
authors.forename: C
authors.initials: C
authors.lastname: Pradhan
authors.forename: S
authors.initials: S
authors.lastname: Sinha
authors.forename: B
authors.initials: B
authors.lastname: Kaveri
authors.forename: K
authors.initials: K
authors.lastname: Thennarasu
authors.forename: B T C
authors.initials: BT
authors.lastname: Murthy
authors.forename: T R
authors.initials: TR
authors.lastname: Raju
mesh_terms: D000328:Adult; D000927:Anticonvulsants / Q000627:therapeutic use; D001341:Autonomic Nervous System / Q000502:physiology* / Q000503:physiopathology; D001945:Breathing Exercises; D015331:Cohort Studies; D003131:Combined Modality Therapy; D004351:Drug Resistance; D004827:Epilepsy / Q000503:physiopathology / Q000628:therapy*; D005081:Exercise Therapy / Q000379:methods*; D005260:Female; D006339:Heart Rate / Q000502:physiology; D006801:Humans; D008297:Male; D012016:Reference Values; D012640:Seizures / Q000503:physiopathology / Q000628:therapy*; D016896:Treatment Outcome; D015013:Yoga
chemical_list: D000927:Anticonvulsants