title: Metal ion promoted cleavage of RNA phosphodiester bonds: from Zn(II) aqua ion to artificial ribonucleases.
abstract: The potential of Zn(2+) azacrown chelates as constituents of artificial ribonucleases is discussed.
authors.affiliation: Department of Chemistry, University of Turku, FIN-20014 Turku, Finland.
authors.forename: Qi
authors.initials: Q
authors.lastname: Wang
authors.forename: Teija
authors.initials: T
authors.lastname: Niittymäki
authors.forename: Pasi
authors.initials: P
authors.lastname: Virta
authors.forename: Kaisa
authors.initials: K
authors.lastname: Ketomäki
authors.forename: Satu
authors.initials: S
authors.lastname: Mikkola
authors.forename: Harri
authors.initials: H
authors.lastname: Lönnberg
mesh_terms: D002384:Catalysis; D047248:Crown Compounds / Q000737:chemistry*; D009942:Organometallic Compounds / Q000737:chemistry*; D010710:Phosphates / Q000737:chemistry; D012260:Ribonucleases / Q000737:chemistry*; D015032:Zinc / Q000737:chemistry*
chemical_list: C511821:1,5,9-triazacyclododecane (12(ane)N3) Zn(II); D047248:Crown Compounds; D009942:Organometallic Compounds; D010710:Phosphates; D012260:Ribonucleases; D015032:Zinc