[Prokinetic agents as a cause of granulomatous interstitial nephritis].
Granulomatous interstitial nephritides are uncommon entities in routine clinical practice. These entities are usually associated with infectious diseases such as tuberculosis, or immune diseases, such as sarcoidosis, systemic lupus erythematosus or cryoglobulinemia. However, these diseases are most frequently associated with drug intake, especially antibiotics, proton pump inhibitors and nonsteroidal anti inflammatory drugs. An association with prokinetic agents has not previously been reported. We report the case of a 64-year-old woman who developed acute renal failure with this histological pattern after taking the motility promoter cinitapride without her physician's knowledge.
Fernández Tagarro
Ernesto J
EJ
Servicio de Nefrología, Hospital Universitario La Paz, Madrid, España.
de Gracia Núñez
Raquel
R
Sánchez Villanueva
Rafael J
RJ
Riñón Aguilar
Carmen
C
Selgas Gutiérrez
Rafael
R
D001549:Benzamides / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008875:Middle Aged; D009395:Nephritis, Interstitial / Q000139:chemically induced*
D001549:Benzamides; C045316:cinitapride