title: 4-Aminopyridine (fampridine) effectively treats amlodipine poisoning: a case report.
abstract: A case of a serious poisoning with the calcium entry blocker amlodipine is described, which was treated effectively with 4-aminopyridine. Calcium is suggested as general treatment of poisoning with calcium entry blockers in many guidelines. The use of intravenous 4-aminopyridine is theoretically useful to treat poisoning from calcium entry blockers and was demonstrated in this case report.
authors.affiliation: Department of Pharmacotherapy and Pharmaceutical Care, GUIDE, University of Groningen, Groningen, The Netherlands. b.wilffert@znb.nl
authors.forename: B
authors.initials: B
authors.lastname: Wilffert
authors.forename: R J
authors.initials: RJ
authors.lastname: Boskma
authors.forename: P H J
authors.initials: PH
authors.lastname: van der Voort
authors.forename: D R A
authors.initials: DR
authors.lastname: Uges
authors.forename: E N
authors.initials: EN
authors.lastname: van Roon
authors.forename: J R B J
authors.initials: JR
authors.lastname: Brouwers
mesh_terms: D015761:4-Aminopyridine / Q000627:therapeutic use*; D017311:Amlodipine / Q000506:poisoning*; D002121:Calcium Channel Blockers / Q000506:poisoning*; D005260:Female; D006801:Humans; D008875:Middle Aged
chemical_list: D002121:Calcium Channel Blockers; D017311:Amlodipine; D015761:4-Aminopyridine