title: Failure of an Abiomed left ventricular assist device in association with factor VIIa administration.
abstract: Factor VIIa might be a useful treatment for coagulopathy and massive hemorrhage following implantation of a mechanical circulatory assist device, but there is a theoretical risk of device thrombosis. To date this complication has not been reported. We describe the first case of clotting of a left ventricular assist device immediately after administration of factor VIIa.
authors.affiliation: Department of Critical Care Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA 15261, USA. mreade@doctors.net.uk
authors.forename: M C
authors.initials: MC
authors.lastname: Reade
authors.forename: Y N
authors.initials: YN
authors.lastname: Toyoda
authors.forename: H N
authors.initials: HN
authors.lastname: Murray
mesh_terms: D000368:Aged; D004868:Equipment Failure; D015942:Factor VIIa / Q000009:adverse effects*; D006353:Heart-Assist Devices; D006801:Humans; D008297:Male; D013927:Thrombosis / Q000139:chemically induced*
chemical_list: D015942:Factor VIIa