Reactivity of 4-tert-butyldimethylsiloxy-1,2,3,6-tetrahydropyridines with hydrazines.
The reactivity of 6-(nitrophenyl or trimethoxyphenyl)-4-tert-butyldimethyl- siloxy-1,2,3,6-tetrahydropyridine derivatives with hydrazines under acid conditions is described. The structure of the products isolated - hydrazones, pyrazolines or pyridazinones - depended on the conditions used. In addition, a systematic study of the reaction outcomes was carried out by introducing variations on the substituents of the tetrahydropyridine ring.
Figueroa
Javier
J
Laboratorio de Química Orgánica y Farmacéutica, Facultad de Farmacia, Campus Miguel de Unamuno, 37007 Salamanca, Spain.
Caballero
Esther
E
Puebla
Pilar
P
Tomé
Fernando
F
Medarde
Manuel
M
D002247:Carbon Isotopes; D006834:Hydrazines / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D011522:Protons; D011725:Pyridines / Q000737:chemistry*; D012833:Siloxanes / Q000737:chemistry*
D002247:Carbon Isotopes; D006834:Hydrazines; D011522:Protons; D011725:Pyridines; D012833:Siloxanes