Pd-catalyzed carbonyl insertion coupling reactions of a hypervalent iodoheterocycle with alcohols and amines.
The palladium-catalyzed cross-coupling carbonyl insertion reaction between 3,7-bis(N,N-dimethylamino)-10H-dibenz[b,e]iodinium iodide (1) and alcohols or amines 2 is described. Some new amides and esters 3 containing an active iodo functional group have been prepared in 65-91% yields.
Luo
Shengj-Jun
SJ
State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, PR China.
Ma
Yong-Xiang
YX
Liang
Yong-Min
YM
D000438:Alcohols / Q000138:chemical synthesis* / Q000737:chemistry; D000588:Amines / Q000138:chemical synthesis* / Q000737:chemistry; D002244:Carbon / Q000737:chemistry*; D002384:Catalysis / Q000187:drug effects; D006571:Heterocyclic Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D017613:Iodine Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D008954:Models, Biological; D010165:Palladium / Q000494:pharmacology*
D000438:Alcohols; D000588:Amines; D006571:Heterocyclic Compounds; D017613:Iodine Compounds; D010165:Palladium; D002244:Carbon