title: [Pain relief].
abstract: Pain in palliative patients demonstrates impact from many dimensions. This article focuses on pain and typical treatment problems in this respect. A pain analysis is mandatory before initiating pharmacological treatment. However, there are often problems with neuropathic and breakthrough pain. A special issue is the possible toxicity of opioids with acute tolerance and central nervous system sensitisation resulting in increased pain intensity. A key word in the treatment of opioid induced problems is opioid rotation. As pain is very dynamic, close monitoring is recommended.
authors.affiliation: Regionshospitalet Herning, Palliativt Team, Herning. heclun@ringamt.dk
authors.forename: Lena E
authors.initials: LE
authors.lastname: Lundorff
authors.forename: Niels-Henrik
authors.initials: NH
authors.lastname: Jensen
mesh_terms: D000698:Analgesia / Q000379:methods; D000701:Analgesics, Opioid / Q000008:administration & dosage / Q000009:adverse effects; D006801:Humans; D009437:Neuralgia / Q000175:diagnosis / Q000188:drug therapy / Q000628:therapy; D010146:Pain / Q000175:diagnosis / Q000188:drug therapy; D059408:Pain Management; D010147:Pain Measurement; D010166:Palliative Care / Q000379:methods
chemical_list: D000701:Analgesics, Opioid