Parasiticidal 2-alkoxy- and 2-aryloxyiminoalkyl trifluoromethanesulfonanilides.
A series of novel 2-alkoxy- and 2-aryloxyiminoalkyl trifluoromethanesulfonanilide derivatives have shown significant in vitro parasiticidal activity against the ectoparasites Ctenocephalides felis and Rhipicephalus sanguineus. A number of these compounds also displayed significant in vitro endoparasite activity against the nematode Haemonchus contortus.
Ali
Abdelselam
A
CSIRO Molecular and Health Technologies, Bag 10, Clayton South, Vic. 3169, Australia.
Altamore
Timothy M
TM
Bliese
Marianne
M
Fisara
Petr
P
Liepa
Andris J
AJ
Meyer
Adam G
AG
Nguyen
Oahn
O
Sargent
Roger M
RM
Sawutz
David G
DG
Winkler
David A
DA
Winzenberg
Kevin N
KN
Ziebell
Angela
A
D000818:Animals; D000977:Antiparasitic Agents / Q000737:chemistry* / Q000494:pharmacology*; D006189:Haemonchus / Q000187:drug effects; D048508:Rhipicephalus sanguineus / Q000187:drug effects*; D005423:Siphonaptera / Q000187:drug effects*; D013329:Structure-Activity Relationship; D013449:Sulfonamides / Q000737:chemistry* / Q000494:pharmacology*
D000977:Antiparasitic Agents; D013449:Sulfonamides; C032898:trifluoromethanesulfonanilide