title: [Nicotine addiction--diagnosis and treatment].
abstract: Smoking consumption prevention is part to the global health strategy of World Health Organisation. Nicotine has important psychotoxic activity but comparing to alcohol and heroin it doesn't determine social disintegrate. Nicotine attaches to specific acetylcholine receptors (nAChR) and their stimulation determines the active substances release. Dopamine release is associated with nicotine-seeking behaviour which provide the passing through "pleasure" to "request". The extent of nicotine dependence is estimated using the Fagestrom test. This is a questionnaire with 6 questions, with a number of points. The highest score is 10, but a score of 7 is associated with high dependence. Nicotine dependence must be regarded as a chronic disease. Practical advice, social support and a safe environment are the main elements of successful therapy.
authors.affiliation: Institutul de Pneumologie Marius Nasta, Bucureşti. imunteanuro@yahoo.com
authors.forename: Ioana
authors.initials: I
authors.lastname: Munteanu
authors.forename: Cristian
authors.initials: C
authors.lastname: Didilescu
mesh_terms: D000465:Algorithms; D004298:Dopamine / Q000378:metabolism; D018765:Dopamine Uptake Inhibitors / Q000494:pharmacology / Q000627:therapeutic use; D006801:Humans; D009538:Nicotine / Q000494:pharmacology; D011594:Psychometrics; D011978:Receptors, Nicotinic / Q000187:drug effects; D016540:Smoking Cessation / Q000379:methods; D012944:Social Support; D011795:Surveys and Questionnaires; D014029:Tobacco Use Disorder / Q000175:diagnosis* / Q000378:metabolism / Q000517:prevention & control / Q000628:therapy*; D014944:World Health Organization
chemical_list: D018765:Dopamine Uptake Inhibitors; D011978:Receptors, Nicotinic; D009538:Nicotine; D004298:Dopamine