title: Self-expanding metallic stents for gastric outlet obstruction resulting from stomach cancer: a preliminary study with a newly designed double-layered pyloric stent.
abstract: BACKGROUND
  Although endoscopic stent placement is now generally accepted as a palliative treatment for gastric outlet obstruction resulting from gastric cancer, it carries potential limitations such as tumor ingrowth or migration.
  
  
  OBJECTIVE
  Our purpose was to evaluate the technical and clinical efficacy of endoscopic placement of a newly designed double-layered combination pyloric stent.
  
  
  METHODS
  Prospective, uncontrolled, single-center.
  
  
  METHODS
  Tertiary referral university hospital.
  
  
  METHODS
  Eleven patients with gastric outlet obstruction by unresectable stomach cancer.
  
  
  METHODS
  Eleven patients received a double-layered combination pyloric stent (an outer uncovered stent to reduce migration and an inner polytetrafluoroethylene-covered stent to prevent tumor ingrowth).
  
  
  METHODS
  To evaluate technical success, clinical success, and complications, especially tumor ingrowth and migration.
  
  
  RESULTS
  Technical success was achieved in 11 of 11 (100%) patients. Among 11 patients in whom endoscopic stenting was placed successfully, clinical success was 90.9%, tumor ingrowth 0%, migration 9.1%, and tumor overgrowth 9.1%. Median stent patency period was 121 days.
  
  
  CONCLUSIONS
  Small number of patients, uncontrolled study, short-term follow-up period.
  
  
  CONCLUSIONS
  We have described a technique for endoscopic metal stent placement by using the newly designed double-layered combination stent for gastric outlet obstruction by stomach cancer. This stent seems to be effective and looks promising for technical efficacy, clinical outcome, and preventing tumor ingrowth and migration.
authors.affiliation: Department of Internal Medicine, Pusan National University College of Medicine, Busan, Korea.
authors.forename: Sun Mi
authors.initials: SM
authors.lastname: Lee
authors.forename: Dae Hwan
authors.initials: DH
authors.lastname: Kang
authors.forename: Gwang Ha
authors.initials: GH
authors.lastname: Kim
authors.forename: Won Il
authors.initials: WI
authors.lastname: Park
authors.forename: Hyong Wook
authors.initials: HW
authors.lastname: Kim
authors.forename: Jin Hong
authors.initials: JH
authors.lastname: Park
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D004867:Equipment Design; D004869:Equipment Safety; D005260:Female; D017219:Gastric Outlet Obstruction / Q000209:etiology* / Q000517:prevention & control / Q000628:therapy; D005773:Gastroscopy / Q000379:methods; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D015607:Stents / Q000639:trends*; D013274:Stomach Neoplasms / Q000150:complications*; D016896:Treatment Outcome