Rhenium-catalyzed hydroamidation of unactivated terminal alkynes: synthesis of (E)-enamides.
Reactions of cyclic amides with unactivated terminal alkynes in the presence of a catalytic amount of a rhenium complex provided (E)-enamides in high regio- and stereoselectivity (E:Z = >99:<1).
Yudha S
Salprima
S
Division of Chemistry and Biochemistry, Graduate School of Natural Science and Technology, Okayama University, Tsushima, Okayama 700-8530, Japan.
Kuninobu
Yoichiro
Y
Takai
Kazuhiko
K