title: Pseudoglandular-type melanoma: a rare melanoma variant.
abstract: We describe a 64-year-old man with a primary nodular melanoma showing unusual histologic features. It consisted entirely of markedly atypical melanocytes arranged in a well-structured glandular pattern. These atypical melanocytes were positive for S-100. This is only the second report of such histology in melanoma, and to our knowledge, the first such case consisting entirely of these features. We review the literature on this rare variant of melanoma.
authors.affiliation: Department of Medicine, New Jersey Medical School, Newark, NJ, USA.
authors.forename: Mordechai M
authors.initials: MM
authors.lastname: Tarlow
authors.forename: Alfred S
authors.initials: AS
authors.lastname: Nemlick
authors.forename: Jerry
authors.initials: J
authors.lastname: Rothenberg
authors.forename: Robert A
authors.initials: RA
authors.lastname: Schwartz
mesh_terms: D000236:Adenoma / Q000473:pathology; D014408:Biomarkers, Tumor / Q000032:analysis; D003131:Combined Modality Therapy; D018572:Disease-Free Survival; D006801:Humans; D008297:Male; D008544:Melanocytes / Q000737:chemistry / Q000473:pathology*; D008545:Melanoma / Q000737:chemistry / Q000473:pathology* / Q000628:therapy; D008875:Middle Aged; D009418:S100 Proteins / Q000032:analysis; D012878:Skin Neoplasms / Q000737:chemistry / Q000473:pathology* / Q000628:therapy; D016896:Treatment Outcome
chemical_list: D014408:Biomarkers, Tumor; D009418:S100 Proteins