Mutation of SBDS and SH2D1A is not associated with aplastic anemia in Japanese children.
During the last decade, the genetic basis of inherited bone marrow failure syndromes has been identified. Recently, genetic factors predisposing to aplastic anemia (AA) have been found in a few patients with apparently acquired AA. Here we present the genetic analysis of SBDS and SH2D1A in Japanese children with AA.
Wang
Yue
Y
Yagasaki
Hiroshi
H
Hama
Asahito
A
Nishio
Nobuhiro
N
Takahashi
Yoshiyuki
Y
Kojima
Seiji
S
D000741:Anemia, Aplastic / Q000235:genetics*; D002648:Child; D006801:Humans; D047908:Intracellular Signaling Peptides and Proteins / Q000235:genetics*; D007564:Japan / Q000453:epidemiology; D009154:Mutation; D011506:Proteins / Q000235:genetics*; D000071179:Signaling Lymphocytic Activation Molecule Associated Protein
D047908:Intracellular Signaling Peptides and Proteins; D011506:Proteins; C470521:SBDS protein, human; C114953:SH2D1A protein, human; D000071179:Signaling Lymphocytic Activation Molecule Associated Protein