A sequential enantioselective, organocatalytic route to chiral 1,2-oxazines and chiral pyridazines.
A sequential, organocatalysed asymmetric reaction to access chiral 1,2-oxazines and chiral pyridazines is reported, which proceeds in moderate to good yields and good to excellent enantioselectivities.
Kumarn
Sirirat
S
Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, UK CB2 1EW.
Oelke
Alexander J
AJ
Shaw
David M
DM
Longbottom
Deborah A
DA
Ley
Steven V
SV
D000447:Aldehydes / Q000737:chemistry; D002384:Catalysis; D007659:Ketones / Q000737:chemistry; D015394:Molecular Structure; D010078:Oxazines / Q000138:chemical synthesis* / Q000737:chemistry; D011724:Pyridazines / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
D000447:Aldehydes; D007659:Ketones; D010078:Oxazines; D011724:Pyridazines