title: Radiofrequency ablation of osseous metastases for the palliation of pain.
abstract: A number of different methods have been proposed for pain relief in cancer patients with bone metastases, each with different indications, contraindications and complications (systemic analgesics, bisphosphonates, antitumor chemotherapy, radiotherapy, systemic radio-isotopes, local surgery and vertebroplasty). The ideal treatment has to be fast, safe, effective and tolerable for the patient. CT-guided radiofrequency (RF) ablation may fulfill these criteria. Our experience in the treatment of 30 patients (34 lesions) with painful bone metastases using RF ablation was assessed. There was a significant decrease in the mean past-24-h Brief Pain Inventory (BPI) score for worst pain, for average pain and for pain interference during daily life (4.7, 4.8 and 5.3 units respectively) 4 and 8 weeks after treatment. There was a marked decrease (3 out of 30 patients 4 and 8 weeks after treatment) in the use of analgesics. CT-guided RF ablation appears to be effective for treatment of painful bone metastases.
authors.affiliation: Department of Interventional Radiology-CT, Hellenic Red Cross Hospital, 1, Athanassaki Street, 115 26 Athens, Greece. loutharad@yahoo.com
authors.forename: L
authors.initials: L
authors.lastname: Thanos
authors.forename: S
authors.initials: S
authors.lastname: Mylona
authors.forename: P
authors.initials: P
authors.lastname: Galani
authors.forename: D
authors.initials: D
authors.lastname: Tzavoulis
authors.forename: V
authors.initials: V
authors.lastname: Kalioras
authors.forename: S
authors.initials: S
authors.lastname: Tanteles
authors.forename: M
authors.initials: M
authors.lastname: Pomoni
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001706:Biopsy; D001859:Bone Neoplasms / Q000556:secondary* / Q000601:surgery*; D017115:Catheter Ablation; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010147:Pain Measurement; D010166:Palliative Care; D015641:Radiography, Interventional; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome