Diastereoselective spiroannulation of phenolic substrates: synthesis of (+/-)-2-tert-butyl-6-methoxy-1-oxaspiro[4,5]deca-6,9-diene-8-one.
The synthesis of a new spiroether is described. The title compound is obtained as a diastereomeric mixture in 45% yield.
Plourde
Guy L
GL
University of Northern British Columbia, Department of Chemistry, Prince George, British Columbia, Canada. plourde@unbc.ca
English
Nadine J
NJ
D003512:Cyclohexanones / Q000138:chemical synthesis*; D005663:Furans / Q000138:chemical synthesis*; D008954:Models, Biological; D008968:Molecular Conformation; D010084:Oxidation-Reduction; D010636:Phenols / Q000737:chemistry*; D013141:Spiro Compounds / Q000138:chemical synthesis* / Q000737:chemistry*
C525951:2-tert-butyl-6-methoxy-1-oxaspiro(4,5)deca-6,9-diene-8-one; D003512:Cyclohexanones; D005663:Furans; D010636:Phenols; D013141:Spiro Compounds