Immunological response in cases of complicated and uncomplicated bartonellosis during pregnancy.
Bartonellosis (Carrion's Disease) during pregnancy is associated with high rates of maternal and perinatal mortality. We report the immunological patterns in two cases of human bartonellosis during pregnancy. One patient had an uncomplicated course while the second patient developed life threatening anasarca and cardiac tamponade. The patient with a complicated course had a Th1 response with a higher elevation of IL-10. This elevation has been associated with poor outcome pregnancies during bacterial infections.
Huarcaya
Erick
E
Department of Family & Community Medicine, University of New Mexico, Albuquerque, NM 87131-0001, USA. ehuarcaya@salud.unm.edu
Maguina
Ciro
C
Best
Ivan
I
Solorzano
Nelson
N
Leeman
Lawrence
L
D000208:Acute Disease; D000328:Adult; D001474:Bartonella Infections / Q000276:immunology*; D016516:CD4-CD8 Ratio; D016207:Cytokines / Q000276:immunology*; D005260:Female; D006801:Humans; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000276:immunology / Q000382:microbiology*
D016207:Cytokines