Increased incidence of mucosal candidiasis after HAART initiation: a benign form of immune reconstitution disease?
Immune reconstitution after HAART initiation is often complicated by adverse clinical manifestations caused either by the unmasking of preexisting untreated opportunistic infections or the clinical deterioration of a known and treated opportunistic infection. The present study was conducted to determine whether the initiation of HAART was followed by an increase in the incidence of mucosal candidiases, a possible manifestation of immune reconstitution disease of the unmasking type.
Nacher
Mathieu
M
COREVIH Cayenne General Hospital, Cayenne, French Guiana.
Vantilcke
Vincent
V
Huber
Florence
F
Mahamat
Aba
A
El Guedj
Myriam
M
Randrianjohany
Andry
A
Clyti
Emmanuel
E
Aznar
Christine
C
Carme
Bernard
B
Couppié
Pierre
P
D017088:AIDS-Related Opportunistic Infections / Q000209:etiology*; D023241:Antiretroviral Therapy, Highly Active / Q000009:adverse effects*; D002177:Candidiasis / Q000453:epidemiology / Q000209:etiology*; D005260:Female; D005616:French Guiana / Q000453:epidemiology; D015658:HIV Infections / Q000188:drug therapy; D015497:HIV-1; D006801:Humans; D054019:Immune Reconstitution Inflammatory Syndrome / Q000453:epidemiology / Q000209:etiology*; D015994:Incidence; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies