title: Easy and Safe preparations of (diacetoxyiodo) arenes from iodoarenes, with urea-hydrogen peroxide adduct (UHP) as the oxidant and the fully interpreted (1)H- and (13)C-NMR spectra of the products.
abstract: An easy and safe, though only moderately effective method is presented for preparing (diacetoxyiodo)arenes, ArI(OAc)2, from iodoarenes, ArI, using the commercially available and easily handled urea-hydrogen peroxide adduct (UHP) as the oxidant. The reactions take place in anhydrous AcOH/Ac2O/AcONa (a catalyst)mixtures, at 40 oC for 3.5 h to afford the purified ArI(OAc)2 in 37-78% yields. The fully interpreted (1)H- and (13)C-NMR spectra of the ArI(OAc)2 products are reported.
authors.affiliation: Chair and Laboratory of Organic Chemistry, Faculty of Pharmacy, Medical University, 1 Banacha Street, PL 02-097 Warsaw, Poland.
authors.forename: Agnieszka
authors.initials: A
authors.lastname: Zielinska
authors.forename: Lech
authors.initials: L
authors.lastname: Skulski
mesh_terms: D000077463:Carbamide Peroxide; D002247:Carbon Isotopes / Q000737:chemistry*; D002625:Chemistry, Organic / Q000379:methods*; D004338:Drug Combinations; D006859:Hydrogen / Q000737:chemistry*; D017613:Iodine Compounds / Q000138:chemical synthesis*; D009682:Magnetic Resonance Spectroscopy; D009281:Naphthalenes / Q000138:chemical synthesis*; D016877:Oxidants / Q000494:pharmacology; D010545:Peroxides / Q000494:pharmacology*; D044366:Transition Temperature; D014508:Urea / Q000031:analogs & derivatives* / Q000494:pharmacology
chemical_list: D002247:Carbon Isotopes; D004338:Drug Combinations; D017613:Iodine Compounds; D009281:Naphthalenes; D016877:Oxidants; D010545:Peroxides; D000077463:Carbamide Peroxide; D006859:Hydrogen; D014508:Urea