title: Antigen presentation the macrophage way.
abstract: Multiphoton intravital microscopy of lymph nodes has revolutionized the study of the early events leading to induction of acquired immunity. Using this technique, Junt et al. (2007) report in a recent issue of Nature that macrophages of the mouse lymph node subcapsular sinus facilitate B cell activation in vivo by collecting and displaying native antigen.
authors.affiliation: Institute of Infection, Immunity and Inflammation, School of Molecular Medical Sciences, University of Nottingham, Queen's Medical Centre, Floor A, West Block, room 1323, Nottingham, NG7 2UH, UK. luisa.martinez-pomares@nottingham.ac.uk
authors.forename: Luisa
authors.initials: L
authors.lastname: Martinez-Pomares
authors.forename: Siamon
authors.initials: S
authors.lastname: Gordon
mesh_terms: D000818:Animals; D017951:Antigen Presentation; D000941:Antigens / Q000276:immunology; D001402:B-Lymphocytes / Q000276:immunology; D008198:Lymph Nodes / Q000166:cytology / Q000276:immunology; D008213:Lymphocyte Activation; D008264:Macrophages / Q000276:immunology / Q000648:ultrastructure; D051379:Mice
chemical_list: D000941:Antigens