The first direct C-H arylation of purine nucleosides.
Pd-catalyzed direct C-H arylation of unprotected purine nucleosides with aryl iodides at position 8 was developed to allow a straightforward single-step introduction of diverse aryl groups.
Cerna
Igor
I
Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Gilead & IOCB Research Center, Flemingovo nam. 2, CZ-16610 Prague 6, Czech Republic.
Pohl
Radek
R
Hocek
Michal
M
D002244:Carbon / Q000737:chemistry*; D006859:Hydrogen / Q000737:chemistry*; D015394:Molecular Structure; D009705:Nucleosides / Q000737:chemistry*; D011687:Purines / Q000737:chemistry*
D009705:Nucleosides; D011687:Purines; D002244:Carbon; D006859:Hydrogen; C030985:purine