Functional magnetic resonance imaging-mediated learning of increased activity in auditory areas.
Our earlier study indicated that functional magnetic resonance imaging (fMRI)-based detection and feedback of regional cortical activity from the auditory area enabled a group of individuals to increase the level of activation mediated by auditory attention during sound stimulation. The long-term ability to maintain an increased level of cortical activation, extending to a time period of a few weeks, however, has not been investigated. We used real-time fMRI to confirm the utility of fMRI in forming a basis for the regulation of brain function to increase the activation in the auditory areas, and demonstrated that the learned ability could be retained after a 2-week period, with additional involvement of an attention-related neural network.
Yoo
Seung-Schik
SS
Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA. yoo@bwh.harvard.edu
Lee
Jong-Hwan
JH
O'Leary
Heather
H
Lee
Vivian
V
Choo
Seh-Eun
SE
Jolesz
Ferenc A
FA
D000161:Acoustic Stimulation; D000328:Adult; D001288:Attention / Q000502:physiology*; D001303:Auditory Cortex / Q000033:anatomy & histology / Q000502:physiology*; D001307:Auditory Perception / Q000502:physiology*; D001931:Brain Mapping; D005260:Female; D007839:Functional Laterality / Q000502:physiology; D006801:Humans; D007858:Learning / Q000502:physiology*; D008279:Magnetic Resonance Imaging; D008297:Male; D009415:Nerve Net / Q000033:anatomy & histology / Q000502:physiology; D009483:Neuropsychological Tests