title: A phylostratigraphy approach to uncover the genomic history of major adaptations in metazoan lineages.
abstract: Macroevolutionary trends traditionally are studied by fossil analysis, comparative morphology or evo-devo approaches. With the availability of genome sequences and associated data from an increasing diversity of taxa, it is now possible to add an additional level of analysis: genomic phylostratigraphy. As an example of this approach, we use a phylogenetic framework and embryo expression data from Drosophila to show that grouping genes by their phylogenetic origin can uncover footprints of important adaptive events in evolution.
authors.affiliation: Division of Molecular Biology, Ruder Bosković Institute, Bijenicka cesta 54, Zagreb, Croatia. tdomazet@irb.hr
authors.forename: Tomislav
authors.initials: T
authors.lastname: Domazet-Loso
authors.forename: Josip
authors.initials: J
authors.lastname: Brajković
authors.forename: Diethard
authors.initials: D
authors.lastname: Tautz
mesh_terms: D000220:Adaptation, Biological / Q000235:genetics; D000818:Animals; D004330:Drosophila / Q000196:embryology / Q000235:genetics*; D019143:Evolution, Molecular; D016678:Genome; D010802:Phylogeny