title: Biomarkers in phase I oncology trials: signal, noise, or expensive distraction?
authors.forename: Mark J
authors.initials: MJ
authors.lastname: Ratain
authors.forename: Robert H
authors.initials: RH
authors.lastname: Glassman
mesh_terms: D014408:Biomarkers, Tumor / Q000032:analysis* / Q000378:metabolism*; D017321:Clinical Trials, Phase I as Topic; D006801:Humans; D009369:Neoplasms / Q000628:therapy*; D011379:Prognosis; D016896:Treatment Outcome
chemical_list: D014408:Biomarkers, Tumor