Pseudoglandular-type melanoma: a rare melanoma variant.
We describe a 64-year-old man with a primary nodular melanoma showing unusual histologic features. It consisted entirely of markedly atypical melanocytes arranged in a well-structured glandular pattern. These atypical melanocytes were positive for S-100. This is only the second report of such histology in melanoma, and to our knowledge, the first such case consisting entirely of these features. We review the literature on this rare variant of melanoma.
Tarlow
Mordechai M
MM
Department of Medicine, New Jersey Medical School, Newark, NJ, USA.
Nemlick
Alfred S
AS
Rothenberg
Jerry
J
Schwartz
Robert A
RA
D000236:Adenoma / Q000473:pathology; D014408:Biomarkers, Tumor / Q000032:analysis; D003131:Combined Modality Therapy; D018572:Disease-Free Survival; D006801:Humans; D008297:Male; D008544:Melanocytes / Q000737:chemistry / Q000473:pathology*; D008545:Melanoma / Q000737:chemistry / Q000473:pathology* / Q000628:therapy; D008875:Middle Aged; D009418:S100 Proteins / Q000032:analysis; D012878:Skin Neoplasms / Q000737:chemistry / Q000473:pathology* / Q000628:therapy; D016896:Treatment Outcome
D014408:Biomarkers, Tumor; D009418:S100 Proteins