Reversible paclitaxel-induced vocal cord paralysis with later recall with vinorelbine.
Described is the first reported case of paclitaxel-induced recurrent laryngeal nerve paralysis in a patient receiving adjuvant therapy for breast cancer. This rare form of neuropathy was reversible at 3 months, but it was re-induced 11 months later when the patient received vinorelbine.
Choi
Brian S
BS
Department of Medicine, University of Wisconsin School of Medicine, 600 Highland Ave, Madison, WI 53792, USA.
Robins
H Ian
HI
D000972:Antineoplastic Agents, Phytogenic / Q000009:adverse effects* / Q000627:therapeutic use; D001943:Breast Neoplasms / Q000150:complications / Q000188:drug therapy; D018270:Carcinoma, Ductal, Breast / Q000150:complications / Q000188:drug therapy; D005260:Female; D006801:Humans; D007823:Laryngeal Nerves / Q000503:physiopathology; D008875:Middle Aged; D009362:Neoplasm Metastasis; D020258:Neurotoxicity Syndromes / Q000503:physiopathology; D017239:Paclitaxel / Q000009:adverse effects* / Q000627:therapeutic use; D010523:Peripheral Nervous System Diseases / Q000139:chemically induced / Q000503:physiopathology; D012008:Recurrence; D014747:Vinblastine / Q000009:adverse effects / Q000031:analogs & derivatives* / Q000627:therapeutic use; D000077235:Vinorelbine; D014826:Vocal Cord Paralysis / Q000139:chemically induced*
D000972:Antineoplastic Agents, Phytogenic; D014747:Vinblastine; D017239:Paclitaxel; D000077235:Vinorelbine