title: Prospective study demonstrating the efficacy of combined preoperative three-day application of antibiotics and povidone-iodine irrigation.
abstract: In 50 patients undergoing anterior segment intraocular surgery we determined that a three-day course of topical ofloxacin followed by preoperative povidone-iodine irrigation caused a marked decrease in the number of conjunctival bacterial flora and resulted in no contamination of the anterior chamber aqueous fluid at the beginning and conclusion of surgery.
authors.affiliation: Department of Ophthalmology, Stanford University, 900 Blake Wilbur Drive, W3036, Stanford, CA 94304, USA. cta@stanford.edu
authors.forename: Christopher N
authors.initials: CN
authors.lastname: Ta
authors.forename: Richard C
authors.initials: RC
authors.lastname: Lin
authors.forename: Gauravjit
authors.initials: G
authors.lastname: Singh
authors.forename: Herminia
authors.initials: H
authors.lastname: Miño de Kaspar
mesh_terms: D000287:Administration, Topical; D000869:Anterior Eye Segment / Q000601:surgery*; D000900:Anti-Bacterial Agents / Q000008:administration & dosage* / Q000627:therapeutic use; D000891:Anti-Infective Agents, Local / Q000008:administration & dosage* / Q000627:therapeutic use; D001082:Aqueous Humor / Q000382:microbiology; D001419:Bacteria / Q000302:isolation & purification; D003228:Conjunctiva / Q000382:microbiology; D004334:Drug Administration Schedule; D006801:Humans; D015242:Ofloxacin / Q000008:administration & dosage* / Q000627:therapeutic use; D013508:Ophthalmologic Surgical Procedures; D011184:Postoperative Period; D011206:Povidone-Iodine / Q000008:administration & dosage* / Q000627:therapeutic use; D011300:Preoperative Care; D011446:Prospective Studies; D007507:Therapeutic Irrigation; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents; D000891:Anti-Infective Agents, Local; D011206:Povidone-Iodine; D015242:Ofloxacin