Nutrition in pediatric lung disease.
The respiratory system exists in an oxygenated milieu and is recurrently exposed to both endogenous and exogenous oxidants and irritants. A variety of dietary-dependent defenses have evolved to protect the lungs. These comprise vitamins, proteins, polyphenols, fatty acids and co-factors. This is a brief review of oxidant sources and the antioxidant system, as pertains to the respiratory system. The challenge to both clinicians and investigators is to understand how defenses are integrated and coordinated so that enhanced protection can be delivered.
Lands
Larry C
LC
McGill University and Pediatric Respiratory Medicine, Montreal Children's Hospital-McGill University Health Centre, Montreal, Canada. larry.lands@muhc.mcgill.ca
D001249:Asthma / Q000503:physiopathology; D002648:Child; D003550:Cystic Fibrosis / Q000503:physiopathology; D005978:Glutathione / Q000378:metabolism; D006801:Humans; D008171:Lung Diseases / Q000378:metabolism / Q000503:physiopathology*; D044342:Malnutrition / Q000503:physiopathology; D009765:Obesity / Q000503:physiopathology; D010084:Oxidation-Reduction; D018384:Oxidative Stress / Q000502:physiology
D005978:Glutathione