Effect of Perftoran on free radical homeostasis during alcohol withdrawal syndrome.
We studied the effects of Perftoran on free radical processes in the liver of rats with withdrawal syndrome after chronic alcohol intoxication. Administration of Perftoran in the period of ethanol withdrawal eliminated the signs of oxidative stress and prevented elevation of enzyme activities in the blood, which reflects improvement of structural and functional characteristics of liver cell membranes.
Miskevich
D A
DA
Laboratory for Regulation of Metabolism, Institute of Biochemistry, National Academy of Sciences of Belarus. mda1977@rambler.ru
Petushok
N E
NE
Gerasimchik
P A
PA
Borodinskii
A N
AN
D000435:Alcoholic Intoxication / Q000378:metabolism*; D000818:Animals; D002908:Chronic Disease; D005466:Fluorocarbons / Q000494:pharmacology*; D005609:Free Radicals / Q000378:metabolism; D006706:Homeostasis; D008099:Liver / Q000201:enzymology; D008297:Male; D018384:Oxidative Stress; D051381:Rats; D017208:Rats, Wistar; D013375:Substance Withdrawal Syndrome / Q000378:metabolism*
D005466:Fluorocarbons; D005609:Free Radicals; C063334:perftoran