Prospective study demonstrating the efficacy of combined preoperative three-day application of antibiotics and povidone-iodine irrigation.
In 50 patients undergoing anterior segment intraocular surgery we determined that a three-day course of topical ofloxacin followed by preoperative povidone-iodine irrigation caused a marked decrease in the number of conjunctival bacterial flora and resulted in no contamination of the anterior chamber aqueous fluid at the beginning and conclusion of surgery.
Ta
Christopher N
CN
Department of Ophthalmology, Stanford University, 900 Blake Wilbur Drive, W3036, Stanford, CA 94304, USA. cta@stanford.edu
Lin
Richard C
RC
Singh
Gauravjit
G
Miño de Kaspar
Herminia
H
D000287:Administration, Topical; D000869:Anterior Eye Segment / Q000601:surgery*; D000900:Anti-Bacterial Agents / Q000008:administration & dosage* / Q000627:therapeutic use; D000891:Anti-Infective Agents, Local / Q000008:administration & dosage* / Q000627:therapeutic use; D001082:Aqueous Humor / Q000382:microbiology; D001419:Bacteria / Q000302:isolation & purification; D003228:Conjunctiva / Q000382:microbiology; D004334:Drug Administration Schedule; D006801:Humans; D015242:Ofloxacin / Q000008:administration & dosage* / Q000627:therapeutic use; D013508:Ophthalmologic Surgical Procedures; D011184:Postoperative Period; D011206:Povidone-Iodine / Q000008:administration & dosage* / Q000627:therapeutic use; D011300:Preoperative Care; D011446:Prospective Studies; D007507:Therapeutic Irrigation; D013997:Time Factors; D016896:Treatment Outcome
D000900:Anti-Bacterial Agents; D000891:Anti-Infective Agents, Local; D011206:Povidone-Iodine; D015242:Ofloxacin