[Analysis of survival rate and risk factors of liver retransplantation].
OBJECTIVE
To analyze the survival rate of orthotopic liver retransplantation (Re-OLT) and identify the variables predicting the outcome.


METHODS
A retrospective analysis of 74 Re-OLT patients from January 1999 to December 2005 was performed. The univariate analysis of Kaplan-Meier model was used to investigate the relativity between the factors and survival rate, and COX regression model was used in multivariate analysis to identify the prognostic factors for survival.


RESULTS
The total incidence rate of Re-OLT was 5.7%, and overall patient survival rates at 1 month, 3 month, 1 year and 2 year were 82.4%, 73.8%, 71.9% and 68.5%, respectively. There were 10 factors might influence the survival rate by Kaplan-Meier model, such as the period of Re-OLT, stage of hepatic encephalopathy, prothrombin time, total bilirubin, warm ischemia time, operative surgical procedure, quantity of blood lost during operation, days staying in the intensive care unit (ICU), infection and complications after Re-OLT. And three factors among them were identified as independent prognostic factors for survival by multivariate model: operative surgical procedure, days staying in the ICU and complications after Re-OLT.


CONCLUSIONS
The surgical procedure, duration in ICU and complications after Re-OLT are strong predictors for survival after Re-OLT.
Zhu
Zhi-Jun
ZJ
Transplant Center, Tianjin First Central Hospital, Tianjin 300192, China. Zhu-zhijun@medmail.com.cn
Rao
Wei
W
Zheng
Hong
H
Deng
Yong-Lin
YL
Zhang
Ya-Min
YM
Zhang
Jian-Jun
JJ
Gao
Wei
W
Pan
Cheng
C
Zhang
Wei-Ye
WY
Huai
Ming-Sheng
MS
Cai
Jin-Zhen
JZ
Shen
Zhong-Yang
ZY
D000293:Adolescent; D000328:Adult; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D053208:Kaplan-Meier Estimate; D016031:Liver Transplantation / Q000401:mortality* / Q000706:statistics & numerical data*; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D011379:Prognosis; D016016:Proportional Hazards Models; D012086:Reoperation / Q000401:mortality / Q000706:statistics & numerical data; D012189:Retrospective Studies; D012307:Risk Factors; D015996:Survival Rate