Microfluidic separation and capture of analytes for single-molecule spectroscopy.
A complex mixture of fluorescently labeled biological molecules is separated electrophoretically on a chip and the constituent molecules are confined in a sub-nanolitre microchamber, which allows analysis by various single-molecule techniques.
Kim
Samuel
S
Department of Chemistry, Stanford University, Stanford, CA 94305-5080, USA.
Huang
Bo
B
Zare
Richard N
RN
D015502:Absorptiometry, Photon; D044085:Microfluidics / Q000295:instrumentation* / Q000379:methods*; D013057:Spectrum Analysis / Q000295:instrumentation* / Q000379:methods*; D019809:Streptavidin
D019809:Streptavidin