title: A facile two-step synthesis of 2-arylbenzofurans based on the selective cross McMurry couplings.
abstract: A novel two-step synthesis of 2-arylbenzofurans has been developed. It involves a selective cross McMurry coupling of a salicylaldehyde or substituted salicylaldehyde with an aromatic aldehyde and a sequential oxidative cyclization of the resulting ortho-vinylphenols. Utilizing this synthetic protocol, a variety of 2-arylbenzofurans including cicerfuran have been efficiently synthesized.
authors.affiliation: Department of Chemistry, Beijing Normal University, Beijing 100875, China xinfangduan@vip.163.com
authors.forename: Xin-Fang
authors.initials: XF
authors.lastname: Duan
authors.forename: Jing
authors.initials: J
authors.lastname: Zeng
authors.forename: Zhan-Bin
authors.initials: ZB
authors.lastname: Zhang
authors.forename: Guo-Fu
authors.initials: GF
authors.lastname: Zi
mesh_terms: D000447:Aldehydes / Q000737:chemistry; D001572:Benzofurans / Q000138:chemical synthesis* / Q000737:chemistry; D003500:Cyclization; D015394:Molecular Structure; D010084:Oxidation-Reduction; D013237:Stereoisomerism
chemical_list: D000447:Aldehydes; D001572:Benzofurans; C515790:cicerfuran