Synthesis of (R)-2-(benzyloxy)-tetrahydro-5,5-dimethylfuran by a new oxidative rearrangement.
The rearrangement under oxidative conditions of 3-(benzyloxy)-tetrahydro- 2,6,6-trimethyl-2H-pyran-2-carbaldehydes to afford a chiral protected tetrahydrofuran lactol is described.
Díez
David
D
Departamento de Química Orgánica,Universidad de Salamanca, Plaza de los Caídos 1-5, 37008 Salamanca, Spain. ddm@usal.es
Nuñez
Marta G
MG
Moro
Rosalina F
RF
Garrido
Narciso M
NM
Marcos
Isidro S
IS
Basabe
Pilar
P
Urones
Julio G
JG
D000447:Aldehydes / Q000737:chemistry; D005663:Furans / Q000138:chemical synthesis* / Q000737:chemistry; D010084:Oxidation-Reduction
C526253:2-(benzyloxy)-tetrahydro-5,5-dimethylfuran; D000447:Aldehydes; D005663:Furans