Ligand-based backbone modifications for metal-chelating nucleic acids.
Ligands were incorporated into the backbone of DNA for nucleoside replacements, and the binding of metal ions, such as Cu2+, Pt2+ and Pd4+, was shown to influence stability of the resulting duplexes.
Knagge
Megan M
MM
Department of Chemistry, Purdue University, West Lafayette, Indiana 47907-2084, USA.
Wilker
Jonathan J
JJ
D001483:Base Sequence; D002614:Chelating Agents / Q000737:chemistry*; D004247:DNA / Q000737:chemistry*; D008024:Ligands; D008670:Metals / Q000378:metabolism*; D008969:Molecular Sequence Data
D002614:Chelating Agents; D008024:Ligands; D008670:Metals; D004247:DNA