title: Simultaneous analysis of circulating human cytokines using a high-sensitivity cytokine biochip array.
abstract: Biochip array technology allows the simultaneous measurement of multiple analytes per sample using a single analytical device. This study shows its applicability to the simultaneous measurement of 12 circulating human cytokines with high-sensitivity detection. This application increases their real-time detectability, maintaining a broad concentration range and without compromising the precision. This methodology represents a very applicable tool in cytokine research when simultaneous determination of minute concentrations can be of interest.
authors.affiliation: Randox Laboratories, 55 Diamond Road, Crumlin, Co Antrim, United Kingdom BT29 4QY.
authors.forename: S Pete
authors.initials: SP
authors.lastname: Fitzgerald
authors.forename: R Ivan
authors.initials: RI
authors.lastname: McConnell
authors.forename: Allen
authors.initials: A
authors.lastname: Huxley
mesh_terms: D002138:Calibration; D016207:Cytokines / Q000097:blood*; D006801:Humans; D046228:Microarray Analysis / Q000379:methods* / Q000592:standards; D012680:Sensitivity and Specificity
chemical_list: D016207:Cytokines