[Severe advanced lower gingival carcinoma effectively reduced by chemoradiation with S-1--report of a case].
Severe advanced head and neck carcinoma which can not be removed via surgical procedure combined with a large lymph node metastasis has a poor prognosis. We administered concurrent chemoradiotherapy with S-1 for a lower gingival carcinoma. As a direct result, we discovered that the treatment greatly reduced the size of tumor, and we consider that this treatment prolonged the patient.s life. The treatment results suggest that the so-called dormancy state of the tumor was continued. In this case study, radiotherapy with S-1 showed a highly effective response from the viewpoint of QOL improvement.
Ishibashi
Miki
M
The First Dept. of Oral and Maxillofacial Surgery, Osaka University Graduate School of Dentistry.
Masuda
Norio
N
Noguchi
Kazuma
K
Moridera
Kuniyasu
K
Nishimura
Norihiko
N
Takayama
Tomoyoshi
T
Nishioji
Kenichi
K
Urade
Masahiro
M
Kogo
Mikihiko
M
D000964:Antimetabolites, Antineoplastic / Q000008:administration & dosage*; D002294:Carcinoma, Squamous Cell / Q000188:drug therapy* / Q000532:radiotherapy*; D003131:Combined Modality Therapy; D004334:Drug Administration Schedule; D004338:Drug Combinations; D005887:Gingival Neoplasms / Q000188:drug therapy* / Q000532:radiotherapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010094:Oxonic Acid / Q000008:administration & dosage*; D011788:Quality of Life; D011879:Radiotherapy Dosage; D005641:Tegafur / Q000008:administration & dosage*
D000964:Antimetabolites, Antineoplastic; D004338:Drug Combinations; C079198:S 1 (combination); D005641:Tegafur; D010094:Oxonic Acid