title: Comparatine analysis of cytophenotypes of cells of mesenchymal lineage isolated from human tissues.
abstract: The expression of cytoplasmic and surface proteins in cultured human skin fibroblasts, human umbilical cord cells obtained after normal delivery on gestation week 38-40, and mesenchymal bone marrow stem cells was compared by the methods of immunocytochemistry and flow cytofluorometry. Bone marrow mesenchymal stem cells expressed a great variety of marker proteins typical of stem and progenitor cells and did not express proteins typical of differentiated cells. Fibroblast-like umbilical cord cells expressed markers of both stem cells and differentiated cells. Fibroblasts of dermal origin were characterized by intensive expression of proteins typical of differentiated cells.
authors.affiliation: Russian State Medical University, Moscow.
authors.forename: Yu G
authors.initials: YG
authors.lastname: Suzdal'tseva
authors.forename: V V
authors.initials: VV
authors.lastname: Burunova
authors.forename: N V
authors.initials: NV
authors.lastname: Petrakova
authors.forename: I V
authors.initials: IV
authors.lastname: Vakhrushev
authors.forename: K N
authors.initials: KN
authors.lastname: Yarygin
authors.forename: V N
authors.initials: VN
authors.lastname: Yarygin
mesh_terms: D001854:Bone Marrow Cells / Q000166:cytology / Q000378:metabolism; D019070:Cell Lineage; D005260:Female; D005347:Fibroblasts / Q000166:cytology / Q000378:metabolism; D006801:Humans; D007150:Immunohistochemistry; D059630:Mesenchymal Stem Cells / Q000166:cytology / Q000378:metabolism; D008648:Mesoderm / Q000166:cytology*; D020543:Proteome / Q000096:biosynthesis; D012867:Skin / Q000166:cytology; D013234:Stem Cells / Q000166:cytology* / Q000378:metabolism; D014470:Umbilical Cord / Q000166:cytology*
chemical_list: D020543:Proteome