Fluctuating asymmetry in dermatoglyphic traits in schizophrenic patients.
OBJECTIVE
The aim of the present study was to establish the validity of fluctuating asymmetry in dermatoglyphic traits as a sign of prenatal injury of schizophrenic patients. MATERIAL AND METHODS. The subjects for this study were 76 schizophrenic inpatients (43 men, 33 women, mean age 31.47 yrs) who satisfied DSM-IV criteria for a diagnosis of schizophrenia and 82 mentally healthy subjects of Bulgarian origin (mean age 39.24 yrs). Fingerprint variables obtained by the ink technique were examined. The fingerprints were read using the method of Cummins and Midlo.


RESULTS
The schizophrenics tended to show higher degree of discordance in the fingerprint patterns and ridge counts on homologous fingers than the control subjects. There were evident sex-related differences between the schizophrenic patients and the control group of subjects.


CONCLUSIONS
Fluctuating asymmetry appears a promising method for study of schizophrenia, which could contribute to the establishment of connection between prenatal exogenous influences and structural brain alterations.
Sivkov
Stefan T
ST
Department of Anatomy, Histology and Embryology, Medical University, Plovdiv, Bulgaria.
Akabaliev
Valentin H
VH
Akabalieva
Katerina V
KV
D000328:Adult; D001921:Brain / Q000002:abnormalities; D001930:Brain Injuries / Q000196:embryology; D016022:Case-Control Studies; D003878:Dermatoglyphics; D005260:Female; D006801:Humans; D008297:Male; D008959:Models, Neurological; D011247:Pregnancy; D049188:Prenatal Injuries; D012559:Schizophrenia / Q000209:etiology / Q000473:pathology*