Sex-linked deafness.
Many human syndromes associated with hearing loss are caused by disease genes located on the X chromosome, but few X-linked loci for non-syndromic hearing loss have been reported. Surprisingly, a Y-linked locus has been identified, representing one of the only disease loci on the Y chromosome. This study reviews the different sex-linked genes and loci on the X- and Y chromosome leading to syndromic and especially non-syndromic hearing loss.
Petersen
M B
MB
Department of Genetics, Institute of Child Health, Athens, Greece.
Wang
Q
Q
Willems
P J
PJ
D002874:Chromosome Mapping; D003638:Deafness / Q000235:genetics; D040181:Genetic Diseases, X-Linked; D050174:Genetic Diseases, Y-Linked; D034381:Hearing Loss / Q000145:classification / Q000235:genetics*; D006801:Humans; D009154:Mutation; D013577:Syndrome