[Lung cavities, mycetomas and hemoptysis].
Pulmonary mycetomas, or fungus balls, consist of spherical masses of mycelia and hyphae, fibrin and granulocytes that grow and partly fill cavitary lesions without invading tissue. They are usually caused by molds of the Aspergillus species, rarely by Mucor or yeast fungi such as Candida species, that colonize damaged lung tissue. Hemoptysis is the most frequent symptom. Since systemic and local administration of antifungal agents is of uncertain efficacy, resectional surgery should be the treatment of choice in cases of severe hemoptysis, if lung function is not severely compromised. As pulmonary resection in the form of lobectomy or pneumonectomy is associated with raised mortality, cavernostomy and cavernoplasty may be options for high-risk patients.
Domej
Wolfgang
W
Infektologie und Klinische Abteilung für Pulmonologie, Universitätsklinik für Innere Medizin, Medizinische Universität Graz, Graz, Osterreich. wolfgang.domej@meduni-graz.at
Hermann
Josef
J
Krause
Robert
R
Wehrschütz
Martin
M
Maier
Alfred
A
Flögel
Erich
E
D001230:Aspergillus; D002175:Candida; D003937:Diagnosis, Differential; D006469:Hemoptysis / Q000209:etiology* / Q000382:microbiology / Q000601:surgery; D006801:Humans; D008172:Lung Diseases, Fungal / Q000175:diagnosis* / Q000382:microbiology / Q000601:surgery; D009089:Mucor; D008271:Mycetoma / Q000175:diagnosis* / Q000382:microbiology / Q000601:surgery; D011013:Pneumonectomy; D014057:Tomography, X-Ray Computed