Weight reduction in renal transplant recipients program: the first successes.
BACKGROUND
Overweight and obesity in kidney graft recipients, both at transplantation and further on, are connected with the development of complications of metabolic syndrome. Hypertension, diabetes, and atherosclerosis are risk factors for chronic allograft nephropathy, shortened graft function, and lower recipient life expectancy. The aim of this study was to present the initial results from a weight reduction in renal transplant recipients program.


METHODS
Thirty-four overweight and obese kidney transplant recipients were enrolled in the study: 9 overweight (26%), 19 obese (55.8%), and 6 morbidly obese (17.6%). The control group encompassed 418 kidney transplant recipients, in whom fluctuations in body mass and body mass index (BMI) were monitored for 56 months.


METHODS
During the first visit, we performed an account of dietary habits and anthropometric measurements. At the second visit following a 6-month interval, patients received dietary guidelines based on an analysis of diet questionnaires.


RESULTS
Six months after enrollment, despite not having received dietary guidelines during the first visit, only 27% of study subjects and 80% of controls experienced weight gain.


CONCLUSIONS
Patients enrolled in the first step of the weight reduction program had no weight nor BMI increase after 6 months. Recipients having experienced body mass increase constituted only 27% of the study group, whereas increase in body mass occurred in 80% of controls. Reducing body mass accretion in kidney transplant recipients should be the target of preventive measures and nonpharmacological therapeutic interventions conducted by qualified personnel. Greater interest by medical personnel in the issue of body mass increase in recipients may be a strong motivating factor for them to undertake weight loss measures.
Jezior
D
D
Department of Nephrology and Transplantation Medicine, Wroclaw Medical University, Wroclaw, Poland. dominikajulial@interia.pl
Krajewska
M
M
Madziarska
K
K
Regulska-Ilow
B
B
Ilow
R
R
Jańczak
D
D
Patrzałek
D
D
Klinger
M
M
D006801:Humans; D016030:Kidney Transplantation / Q000009:adverse effects* / Q000502:physiology; D024821:Metabolic Syndrome / Q000209:etiology / Q000517:prevention & control; D009765:Obesity / Q000209:etiology* / Q000534:rehabilitation; D009767:Obesity, Morbid / Q000209:etiology / Q000534:rehabilitation; D050177:Overweight / Q000209:etiology* / Q000534:rehabilitation; D011183:Postoperative Complications / Q000517:prevention & control; D016896:Treatment Outcome; D015431:Weight Loss