title: Preoperative pulmonary rehabilitation in patients undergoing lung resection for non-small cell lung cancer.
abstract: BACKGROUND
  The impact of short-term preoperative pulmonary rehabilitation on exercise capacity of patients with chronic obstructive pulmonary disease undergoing lobectomy for non-small cell lung cancer is evaluated.
  
  
  METHODS
  A prospective observational study was designed. Inclusion criteria consisted of an indication to lung resection because of a clinical stage I or II non-small cell lung cancer and a chronic obstructive disease on preoperative pulmonary function test. In such conditions, maximal oxygen consumption by a cardio-pulmonary exercise test was evaluated; when this resulted as being < or =15 ml/kg/min a pulmonary rehabilitation programme lasting 4 weeks was considered. Twelve patients fulfilled inclusion criteria, completed the preoperative rehabilitation programme and underwent a new functional evaluation prior to surgery. The postoperative record of these patients was collected.
  
  
  RESULTS
  On completion of pulmonary rehabilitation, the resting pulmonary function test and diffuse lung capacity of patients was unchanged, whereas the exercise performance was found to have significantly improved; the mean increase in maximal oxygen consumption proved to be at 2.8 ml/kg/min (p<0.01). Eleven patients underwent lobectomy; no postoperative mortality was noted and mean hospital stay was 17 days. Postoperative pulmonary complication was recorded in 8 patients.
  
  
  CONCLUSIONS
  Short-term preoperative pulmonary rehabilitation could improve the exercise capacity of patients with chronic obstructive pulmonary disease who are candidates for lung resection for non-small cell lung cancer.
authors.affiliation: Section of Thoracic Surgery, Department of Surgical Sciences, University Hospital of Parma, Parma, Italy. antonio.bobbio@unipr.it
authors.forename: Antonio
authors.initials: A
authors.lastname: Bobbio
authors.forename: Alfredo
authors.initials: A
authors.lastname: Chetta
authors.forename: Luca
authors.initials: L
authors.lastname: Ampollini
authors.forename: Gian Luca
authors.initials: GL
authors.lastname: Primomo
authors.forename: Eveline
authors.initials: E
authors.lastname: Internullo
authors.forename: Paolo
authors.initials: P
authors.lastname: Carbognani
authors.forename: Michele
authors.initials: M
authors.lastname: Rusca
authors.forename: Dario
authors.initials: D
authors.lastname: Olivieri
mesh_terms: D000368:Aged; D002289:Carcinoma, Non-Small-Cell Lung / Q000601:surgery*; D015444:Exercise / Q000502:physiology*; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000601:surgery*; D008297:Male; D010865:Pilot Projects; D011183:Postoperative Complications / Q000517:prevention & control*; D011237:Predictive Value of Tests; D011300:Preoperative Care / Q000379:methods*; D011446:Prospective Studies; D029424:Pulmonary Disease, Chronic Obstructive / Q000534:rehabilitation*; D012129:Respiratory Function Tests / Q000379:methods; D016896:Treatment Outcome