[Studies on chemical constituents in seeds of Cicer arietinum].
OBJECTIVE
To study the chemical constituents in seeds of Cicer arietinum, so that to find bioactive natural products.


METHODS
Dried and sprouted seeds of C. arietinum were extracted with ethanol of various concentrations respectively, then isolated and purified by silica gel, macroreticular resin D 101, Sephadex LH -20 gel column chromatography, and structures of compounds were identified by spectral analysis.


RESULTS
Nine compounds have been isolated and identified: 3-hydroxy-olean-12-ene (1), biochanin A-7-O-beta-D-glucoside (2), cerebroside (3), 1-ethyl-alpha-L-galactoside (4), uridine (5), adenosine (6), trytophan (7), biochanin A (8), fomononetin (9).


CONCLUSIONS
Compounds 1, 3, 4, 6, 7 were isolated from genus Cicer for the first time.
Tan
Yong-xia
YX
Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine (Ministry of Education), Institute of Materia Medica, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100050, China.
Sun
Yu-hua
YH
Chen
Ruo-yun
RY
D000241:Adenosine / Q000737:chemistry / Q000302:isolation & purification*; D002554:Cerebrosides / Q000737:chemistry / Q000302:isolation & purification*; D002850:Chromatography, Gel; D029863:Cicer / Q000737:chemistry*; D010946:Plants, Medicinal / Q000737:chemistry*; D012639:Seeds / Q000737:chemistry; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification*
D002554:Cerebrosides; D014315:Triterpenes; D000241:Adenosine