title: Cost assessment of the automated VERSANT 440 Molecular System versus the semi-automated System 340 bDNA Analyzer platforms.
abstract: Labor, supply and waste were evaluated for HIV-1 and HCV bDNA on the semi-automated System 340 bDNA Analyzer and the automated VERSANT 440 Molecular System (V440). HIV-1 sample processing was evaluated using a 24- and 48-position centrifuge rotor. Vigilance time (hands-on manipulations plus incubation time except initial target hybridization) and disposables were approximately 37 and 12% lower for HIV-1, and 64 and 31% lower for HCV bDNA, respectively, with V440. Biohazardous solid waste was approximately twofold lower for both assays and other waste types were the same for either assay on both platforms. HIV-1 sample processing vigilance time for the 48-position rotor was reduced by 2 h. V440 provides cost savings and improved workflow.
authors.affiliation: Professional Habitat Design, LLC; Health Management Institute, Inc., c/o 584 Castro Street 349, San Francisco, CA 94114, USA. t.elbeik@phdllc.net
authors.forename: Tarek
authors.initials: T
authors.lastname: Elbeik
authors.forename: Richard A
authors.initials: RA
authors.lastname: Loftus
authors.forename: Scott
authors.initials: S
authors.lastname: Beringer
mesh_terms: D021121:Branched DNA Signal Amplification Assay / Q000191:economics / Q000295:instrumentation / Q000379:methods / Q000592:standards; D003365:Costs and Cost Analysis; D004279:DNA, Viral / Q000032:analysis*; D015658:HIV Infections / Q000175:diagnosis / Q000191:economics; D015497:HIV-1 / Q000235:genetics / Q000378:metabolism; D006801:Humans; D019562:Viral Load
chemical_list: D004279:DNA, Viral