Acute renal failure due to acute tubular necrosis caused by direct invasion of Orientia tsutsugamushi.
We describe a scrub typhus patient with acute renal failure for whom a diagnosis was made based on serology as well as immunohistochemical (IHC) staining and an electron microscopic examination (EM) of a renal biopsy specimen. For our case, we demonstrated by IHC staining and EM that renal failure was caused by acute tubular necrosis due to a direct invasion of Orientia tsutsugamushi.
Kim
Dong-Min
DM
Department of Internal Medicine, Chosun University College of Medicine, 588 Seosuk-dong, Dong-gu, Gwangju 501-717, South Korea.
Kang
Dae Woong
DW
Kim
Jong O
JO
Chung
Jong Hoon
JH
Kim
Hyun Lee
HL
Park
Chi Young
CY
Lim
Sung-Chul
SC
D058186:Acute Kidney Injury / Q000209:etiology* / Q000382:microbiology / Q000473:pathology; D000328:Adult; D006801:Humans; D007150:Immunohistochemistry; D007683:Kidney Tubular Necrosis, Acute / Q000209:etiology / Q000382:microbiology* / Q000473:pathology; D008297:Male; D008854:Microscopy, Electron; D012285:Orientia tsutsugamushi / Q000302:isolation & purification / Q000472:pathogenicity*; D012612:Scrub Typhus / Q000150:complications* / Q000382:microbiology