Septins: cellular and functional barriers of neuronal activity.
How conserved is sub-cellular compartmentalization across species and does it play a similar role? Here, two studies now demonstrate that buds in yeast and spines in mammalian neurons share many properties and suggest unexpected commonalities between simple and complex organisms.
Barral
Yves
Y
Department of Biology, ETH Zürich, 8093 Zürich, Switzerland. yves.barral@bc.biol.ethz.ch
Mansuy
Isabelle M
IM
D000818:Animals; D003598:Cytoskeletal Proteins / Q000737:chemistry / Q000502:physiology*; D049229:Dendritic Spines / Q000201:enzymology / Q000502:physiology*; D020558:GTP Phosphohydrolases / Q000737:chemistry / Q000502:physiology*; D009474:Neurons / Q000166:cytology* / Q000201:enzymology* / Q000502:physiology; D029701:Saccharomyces cerevisiae Proteins / Q000737:chemistry / Q000502:physiology
D003598:Cytoskeletal Proteins; D029701:Saccharomyces cerevisiae Proteins; D020558:GTP Phosphohydrolases