title: [Pediatric patient in adult age. Long-terms results of esophageal replacement].
abstract: BACKGROUND
  Esophagocoloplasty is one of the most used procedures for esophageal replacement in children. Considering high life expectancy in these patients, long-term results must be considered when evaluating this technique. The aim of our study is to evaluate quality of life of adult patients who underwent surgery at pediatric age.
  
  
  METHODS
  We report a retrospective study of 99 patients who underwent esophageal replacement in our institution between 1966 and 2006. Eight of them have died and 63 out of the remaining 91 are over 18 years now and represent our study serie. Long-term results and actual situation of those patients, considering psychological, physic and social aspects, were evaluated through clinical review and telephonic interview. Karnofsky index was applied to mesure functional ability from 0-100% (bad, medium, good-excellent) according to the answers the patients gave to our questions. We also recorded their health personal experience and subjective evaluation of their quality of life.
  
  
  RESULTS
  Sixty-three patients were reviewed (43 males and 20 females) with a mean age of 4.3 +/- 3.4 D.S. Mean follow-up time was 29.6 +/-7.7 years. Indications for esophageal replacement were as follows: caustication (n = 32), type III esophageal atresia (n = 15), type I AE (n = 13) and others (n = 3). In 48 patients the graft was placed in retroestenal position and in 15 cases retromediastic location was used. Postoperative period was uneventful in 44% of the patients, being the most frequent early complications in the remaining, cervical leakage and stenosis. Long-term, 56,8% did not have any sequelae, 28.5% required further surgery and the remaining 43.13% presented the following complications: symptomatic graft reflux (22), scoliosis and thoracic asymmetry (12), colonic redundancy or cervical diverticulum (7), food impaction (6) and failure to thrive (5). Only one 38 year old patient does not have intestinal tract continuity nowadays. Thirty-one patients have a Karnofsky index > or = 80-100%, being considered healthy and able to have a normal activity. Eighteen patients are included between 40-80%, being the most frequent limitation the need of medication to avoid reflux, backache and occasional episodes of food impact. Only 2 patients have Karnofsky index inferior to 40%. None of them are under 20%.
  
  
  CONCLUSIONS
  Esophagocoloplasty allows restoration of intestinal tract continuity in almost all cases and the mortality of this procedure has decreased over time. Even though some risks are still remarkable, it offers long-term good results with little repercussion on functional ability in adult age. Most of the patients consider themselves healthy and enjoy an acceptable quality of life.
authors.affiliation: Departamento de Cirugía Pediátrica, Hospital Infantil La Paz, Madrid. lauraburgos33@hotmail.com
authors.forename: L
authors.initials: L
authors.lastname: Burgos
authors.forename: L
authors.initials: L
authors.lastname: Martínez
authors.forename: O
authors.initials: O
authors.lastname: Suárez
authors.forename: A M
authors.initials: AM
authors.lastname: Andrés
authors.forename: A L
authors.initials: AL
authors.lastname: Luis
authors.forename: J L
authors.initials: JL
authors.lastname: Encinas
authors.forename: F
authors.initials: F
authors.lastname: Hernández
authors.forename: J
authors.initials: J
authors.lastname: Murcia
authors.forename: P
authors.initials: P
authors.lastname: Olivares
authors.forename: A
authors.initials: A
authors.lastname: Queizán
authors.forename: L
authors.initials: L
authors.lastname: Lassaletta
authors.forename: J A
authors.initials: JA
authors.lastname: Tovar
mesh_terms: D003106:Colon / Q000637:transplantation*; D004935:Esophageal Diseases / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D011788:Quality of Life; D012189:Retrospective Studies; D011795:Surveys and Questionnaires; D013997:Time Factors