title: A concise organocatalytic and enantioselective synthesis of isotetronic acids.
abstract: A concise enantioselective route to isotetronic acids using an organocatalyzed aldol reaction between alpha-oxocarboxylic acids and aldehydes has been developed, leading to the titled compounds in reasonable yields and good enantioselectivities.
authors.affiliation: University Bordeaux-1, CNRS-UMR 5255, Institut des Sciences Moléculaires, 351, cours de la libération, 33405 Talence, France. jm.vincent@ism.u-bordeaux1.fr
authors.forename: Jean-Marc
authors.initials: JM
authors.lastname: Vincent
authors.forename: Chrystèle
authors.initials: C
authors.lastname: Margottin
authors.forename: Muriel
authors.initials: M
authors.lastname: Berlande
authors.forename: Dominique
authors.initials: D
authors.lastname: Cavagnat
authors.forename: Thierry
authors.initials: T
authors.lastname: Buffeteau
authors.forename: Yannick
authors.initials: Y
authors.lastname: Landais
mesh_terms: D000079:Acetaldehyde / Q000031:analogs & derivatives / Q000737:chemistry; D000447:Aldehydes / Q000737:chemistry; D002384:Catalysis; D002942:Circular Dichroism; D005663:Furans / Q000138:chemical synthesis* / Q000737:chemistry; D008958:Models, Molecular; D015394:Molecular Structure; D013237:Stereoisomerism
chemical_list: D000447:Aldehydes; D005663:Furans; C038235:bromoacetaldehyde; C116609:3-hydroxybutanal; D000079:Acetaldehyde; C003422:tetronic acid