Nationwide study of the prevalence, characteristics, and molecular epidemiology of extended-spectrum-beta-lactamase-producing Enterobacteriaceae in France.
Among 10,872 isolates of Enterobacteriaceae from a nationwide study of 88 French hospitals in 2005, 169 (1.7%) expressed an extended-spectrum beta-lactamase. The most prevalent species were Escherichia coli (48.5%), Enterobacter aerogenes (23.7%), and Klebsiella pneumoniae (14.8%). Molecular analysis underlined the polyclonal spread of CTX-M-expressing E. coli, primarily isolates of the CTX-M-1 subgroup.
Galas
Muriel
M
Service d'Hygiène Hospitalière, Centre Hospitalier de Versailles, Le Chesnay, France.
Decousser
Jean-Winoc
JW
Breton
Nelly
N
Godard
Thierry
T
Allouch
Pierre Yves
PY
Pina
Patrick
P
D004755:Enterobacteriaceae / Q000145:classification / Q000187:drug effects / Q000201:enzymology* / Q000235:genetics; D004756:Enterobacteriaceae Infections / Q000453:epidemiology* / Q000382:microbiology; D004926:Escherichia coli / Q000201:enzymology / Q000235:genetics; D005602:France / Q000453:epidemiology; D008826:Microbial Sensitivity Tests; D017720:Molecular Epidemiology; D015995:Prevalence; D018440:beta-Lactam Resistance; D001618:beta-Lactamases / Q000096:biosynthesis* / Q000145:classification / Q000235:genetics; D047090:beta-Lactams
D047090:beta-Lactams; C055184:beta-lactamase TEM-3; D001618:beta-Lactamases