title: SAXS measurement of aggregate of DNA modified gold nanoparticles.
abstract: DNA-modified gold nanoparticles exhibit a unique aggregation behaviour that they form aggregation with fully complementary DNA but do not with the terminal-mismatched DNA at certain concentration of added salts. We studied the aggregation structure of the nanoparticles by small angle X-ray scattering (SAXS). The results indicated that the gap between surfaces of gold nanoparticles is nearly two times as long as DNA in B-form. This suggests that the ends of completely double-stranded DNA (dsDNA) conjugated on gold nanoparticles contact or slightly interdigitate with each other in the aggregation structure.
authors.affiliation: Graduate School of Frontier Sciences, The University of Tokyo, 5-1-5 Kashiwanoha, Kashiwa, Chiba 277-8561, Japan. sizuto@molle.k.u-tokyo.ac.jp
authors.forename: Shizuto
authors.initials: S
authors.lastname: Yamakoshi
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Sakai
authors.forename: Yuya
authors.initials: Y
authors.lastname: Shinohara
authors.forename: Yoshiyuki
authors.initials: Y
authors.lastname: Amemiya
authors.forename: Naoki
authors.initials: N
authors.lastname: Kanayama
authors.forename: Tohru
authors.initials: T
authors.lastname: Takarada
authors.forename: Mizuo
authors.initials: M
authors.lastname: Maeda
authors.forename: Kohzo
authors.initials: K
authors.lastname: Ito
mesh_terms: D004247:DNA / Q000737:chemistry*; D006046:Gold / Q000737:chemistry*; D053768:Metal Nanoparticles / Q000737:chemistry*; D009690:Nucleic Acid Conformation; D053838:Scattering, Small Angle; D014961:X-Ray Diffraction
chemical_list: D006046:Gold; D004247:DNA