title: Bone mineral density estimation using the filling factor of the radius X-ray image.
abstract: Osteoporosis is characterized by an abnormal loss of bone mineral content, which leads to a tendency to non-traumatic bone fractures or to structural deformations of bone. Thus, bone density measurement has been considered as a most reliable method to assess bone fracture risk due to osteoporosis. In past decades, x-ray images have been studied in connection with the bone mineral density estimation. However, the estimated bone mineral density from the x-ray image can undergo a relatively large accuracy or precision error. The most relevant origin of the accuracy or precision error may be unstable x-ray image acquisition condition. In the previous study, we presented a bone mineral density estimation method that uses the trabecular bone filling factor in the radius x-ray image and that is relatively insensitive to the x-ray image acquisition condition. In this paper, we investigate the method using larger patient data and point out a preliminary result related to the fracture risk prediction using the method.
authors.affiliation: Electronics and Telecommunications Research Institute, Daejeon, 305-700, Korea.
authors.forename: Sooyeul
authors.initials: S
authors.lastname: Lee
authors.forename: Ji-Wook
authors.initials: JW
authors.lastname: Jeong
authors.forename: Jeong Won
authors.initials: JW
authors.lastname: Lee
authors.forename: Done-Sik
authors.initials: DS
authors.lastname: Yoo
authors.forename: Seunghwan
authors.initials: S
authors.lastname: Kim
mesh_terms: D015502:Absorptiometry, Photon / Q000379:methods*; D015519:Bone Density; D005260:Female; D006801:Humans; D010024:Osteoporosis / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D011857:Radiographic Image Interpretation, Computer-Assisted / Q000379:methods*; D011885:Radius Fractures / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D015203:Reproducibility of Results; D018570:Risk Assessment / Q000379:methods; D012307:Risk Factors; D012680:Sensitivity and Specificity