The antiphospholipid syndrome.
The antiphospholipid syndrome (APS) is an autoimmune thrombophilic condition that is marked by the presence of antibodies that recognize phospholipid-binding proteins. The clinical manifestations of APS include vascular thrombosis and pregnancy complications, especially recurrent spontaneous miscarriages. This article provides an update on diagnostic and therapeutic approaches to this disorder.
Rand
Jacob H
JH
Department of Pathology, Montefiore Medical Center, 111 East 210th St, Bronx, NY 10467, USA. jrand@montefiore.org
D016736:Antiphospholipid Syndrome / Q000150:complications / Q000175:diagnosis*; D005260:Female; D006801:Humans; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000628:therapy; D013927:Thrombosis / Q000209:etiology / Q000628:therapy