title: Pernicious anaemia in triplets. A case report and literature review.
abstract: Pernicious anemia is the most common cause of vitamin B12 deficiency in adults. This entity is associated with chronic atrophic gastritis. We report a case of pernicious anaemia in triplets. We also report a fourth case of cobalamin deficiency with antibodies against intrinsic factor and anti parietal cell antigen negative antibodies in a sibling. The present article reviews the pediatric presentation of pernicious anemia and highlights the possible existence of familial aggregation. Furthermore, the need for systematic familial screening and the usefulness of an endoscopic follow-up program in patients with pernicious anemia are evaluated.
authors.affiliation: Department of Gastroenterology, Hospital Universitari Germans Trias i Pujol, Badalona, Barcelona, Spain.
authors.forename: Helena
authors.initials: H
authors.lastname: Masnou
authors.forename: Eugeni
authors.initials: E
authors.lastname: Domènech
authors.forename: Mercè
authors.initials: M
authors.lastname: Navarro-Llavat
authors.forename: Yamile
authors.initials: Y
authors.lastname: Zabana
authors.forename: Míriam
authors.initials: M
authors.lastname: Mañosa
authors.forename: Esther
authors.initials: E
authors.lastname: García-Planella
authors.forename: Miquel A
authors.initials: MA
authors.lastname: Gassull
mesh_terms: D000328:Adult; D000752:Anemia, Pernicious / Q000175:diagnosis*; D002648:Child; D005260:Female; D006801:Humans