Investigations into the use of a polyfluorooctanol as an auxiliary component for an aldol reaction.
Results are reported on the efficiency of polyfluorooctanol as a perfluorous auxiliary component in the aldol reaction between the enolate derived from polyfluorooctyl acetate and 2-fluorobenzaldehyde. Reduction of the corresponding polyfluoro beta-hydroxy ester with Super Hydride gave the required 1,3-diol in good yield.
Eames
Jason
J
Department of Chemistry, Queen Mary, University of London, London E1 4NS, UK. J.Eames@qmul.ac.uk
Khanom
Hasina
H
D000447:Aldehydes / Q000737:chemistry*; D002384:Catalysis; D006845:Hydrocarbons, Fluorinated / Q000737:chemistry*; D008956:Models, Chemical; D015394:Molecular Structure; D013237:Stereoisomerism
D000447:Aldehydes; D006845:Hydrocarbons, Fluorinated