Report of a novel B*3579 allele in an Ecuadorian family: confirmation and extension of A*6836 and B*3922 sequences.
Human leukocyte antigen (HLA) class I sequencing typing of a cord blood unit obtained from an Ecuadorian family showed the presence of the recently described A*6836 and B*3922 alleles. Sequences of these two antigens were confirmed and completed. Additionally, a new HLA-B allele, B*3579, was found in the same family, showing a difference of one amino acid residue at position 211 (Ala > Glu) compared with B*3543.
Sánchez-Gordo
F
F
Departamento de Histocompatibilidad, Centro de Transfusión de Málaga, Málaga, Spain.
Balas
A
A
García-Sánchez
F
F
Prat
I
I
Vicario
J L
JL
D000328:Adult; D000483:Alleles; D000595:Amino Acid Sequence; D001483:Base Sequence; D004484:Ecuador; D005260:Female; D015234:HLA-A Antigens / Q000235:genetics*; D015797:HLA-B35 Antigen / Q000235:genetics*; D006801:Humans; D007231:Infant, Newborn; D008969:Molecular Sequence Data; D017422:Sequence Analysis, DNA
D015234:HLA-A Antigens; D015797:HLA-B35 Antigen