title: Informed consent and assent in human subject research.
abstract: Informed consent is an important aspect of human subject research, designed to uphold individual autonomy and the moral principle of respect for persons. The National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research articulates three distinct elements of informed consent as "information, comprehension, and voluntariness." These elements are discussed as they apply to informed consent. This article then discusses the concept of child assent. Finally, informed consent as it applies to public health research is discussed.
authors.affiliation: Medical College of Wisconsin, Milwoaukee, USA.
authors.forename: G L
authors.initials: GL
authors.lastname: Johnson
authors.forename: R M
authors.initials: RM
authors.lastname: Nelson
mesh_terms: D006805:Human Experimentation; D006801:Humans; D007258:Informed Consent / Q000592:standards*; D014481:United States