WNT5A is epigenetically silenced in hematologic malignancies and inhibits leukemia cell growth as a tumor suppressor.
Ying
Jianming
J
Li
Hongyu
H
Chen
Yun-Wen
YW
Srivastava
Gopesh
G
Gao
Zifen
Z
Tao
Qian
Q
D045744:Cell Line, Tumor; D044127:Epigenesis, Genetic; D015973:Gene Expression Regulation, Leukemic; D020868:Gene Silencing; D019337:Hematologic Neoplasms / Q000235:genetics / Q000378:metabolism* / Q000473:pathology; D006801:Humans; D007938:Leukemia / Q000235:genetics / Q000378:metabolism* / Q000473:pathology; D011518:Proto-Oncogene Proteins / Q000096:biosynthesis* / Q000235:genetics; D025521:Tumor Suppressor Proteins / Q000096:biosynthesis* / Q000235:genetics; D051153:Wnt Proteins / Q000096:biosynthesis* / Q000235:genetics; D000071818:Wnt-5a Protein
D011518:Proto-Oncogene Proteins; D025521:Tumor Suppressor Proteins; C085389:WNT5A protein, human; D051153:Wnt Proteins; D000071818:Wnt-5a Protein