Feline cutaneous viral papilloma associated with human papillomavirus type 9.
A 12-year-old domestic Shorthaired cat developed a multinodular exophytic mass on the dorsal surface of the nose. The skin surrounding the mass was nonpigmented, and actinic keratosis had been diagnosed in this area 3 years previously. Histologic examination revealed hyperkeratosis, epidermal hyperplasia, papillomatosis, koilocytosis, and possible intranuclear viral inclusions. Polymerase chain reaction amplified papillomaviral deoxyribonucleic acid from formalin-fixed samples of the lesion. Sequencing of the amplicon revealed 98% similarity to human papillomavirus (HPV) type 9. To the authors' knowledge, this is only the second reported feline cutaneous viral papilloma. In addition, this is the first report of a feline papilloma being associated with an HPV.
Institute of Veterinary, Animal and Biomedical Sciences, Massey University, Private Bag 11 222, Palmerston North, New Zealand. J.Munday@massey.ac.nz
J S
JS
Munday
E M
EM
Hanlon
L
L
Howe
R A
RA
Squires
A F
AF
French
D052685:Alphapapillomavirus / Q000302:isolation & purification*; D000818:Animals; D002371:Cat Diseases / Q000473:pathology / Q000821:virology*; D002415:Cats; D010212:Papilloma / Q000473:pathology / Q000662:veterinary* / Q000821:virology; D012878:Skin Neoplasms / Q000473:pathology / Q000662:veterinary* / Q000821:virology