Treatment of a large periradicular lesion of endodontic origin around a dental implant with enamel matrix protein derivative.
BACKGROUND
This case report describes the healing of a large periradicular lesion involving an adjacent implant. Endodontic surgery was performed in combination with placement of an enamel matrix protein derivative.


METHODS
Endodontic surgery was performed, including root end resection at a 90 degrees angle. Ultrasonic tips were used for retrograde preparation, and the retrograde cavity was sealed with zinc oxide-eugenol. The area was filled carefully with enamel matrix proteins. Sutures were removed after a 2-week healing period.


RESULTS
There were no symptoms of pain, inflammation, or discomfort at 18 months post-surgery. Radiographs showed complete healing of the periradicular lesion.


CONCLUSIONS
Combining an enamel matrix protein derivative with conventional surgery may improve the clinical outcome of large endodontic lesions. Additional research is warranted.
Endodontics and Dental Trauma Unit, Department of Oral and Dental Medicine, Rambam Medical Center, Haifa, Israel. linsn@post.tau.ac.il
Shaul
S
Lin
Yaniv
Y
Mayer
D001047:Apicoectomy; D001861:Bone Regeneration / Q000187:drug effects; D003746:Dental Enamel Proteins / Q000627:therapeutic use*; D015921:Dental Implants; D005260:Female; D006801:Humans; D008875:Middle Aged; D010484:Periapical Granuloma / Q000188:drug therapy* / Q000601:surgery*; D012184:Retrograde Obturation
D003746:Dental Enamel Proteins; D015921:Dental Implants; C109069:enamel matrix proteins