Functional magnetic resonance imaging of language in epilepsy.
Functional magnetic resonance imaging (fMRI) has revolutionized our understanding of functional networks and cerebral organization in both normal and pathological brains. In the present review, we describe the use of fMRI for mapping language in epilepsy patients prior to surgical intervention including a discussion of methodological issues and task design, comparisons between fMRI and the intracarotid sodium amobarbital test, fMRI studies of language reorganization, and the use of fMRI laterality indexes to predict outcome after anterior temporal lobectomy.
Department of Neurology, Medical College of Wisconsin, Milwaukee, WI, USA. sswanson@mcw.edu
Sara J
SJ
Swanson
David S
DS
Sabsevitz
Thomas A
TA
Hammeke
Jeffrey R
JR
Binder
D001931:Brain Mapping; D002540:Cerebral Cortex / Q000502:physiology* / Q000503:physiopathology / Q000601:surgery; D004827:Epilepsy / Q000503:physiopathology* / Q000601:surgery; D007839:Functional Laterality; D006801:Humans; D007802:Language; D007806:Language Disorders / Q000209:etiology / Q000517:prevention & control*; D008279:Magnetic Resonance Imaging; D019635:Neurosurgical Procedures / Q000009:adverse effects; D011183:Postoperative Complications / Q000209:etiology / Q000517:prevention & control