Inorganic: the other mercury.
There is a broad array of mercury species to which humans may be exposed. While exposure to methylmercury through fish consumption is widely recognized, the public is less aware of the sources and potential toxicity of inorganic forms of mercury. Some oral and laboratory thermometers, barometers, small batteries, thermostats, gas pressure regulators, light switches, dental amalgam fillings, cosmetic products, medications, cultural/religious practices, and gold mining all represent potential sources of exposure to inorganic forms of mercury. The route of exposure, the extent of absorption, the pharmacokinetics, and the effects all vary with the specific form of mercury and the magnitude and duration of exposure. If exposure is suspected, a number of tissue analyses can be conducted to confirm exposure or to determine whether an exposure might reasonably be expected to be biologically significant. By contrast with determination of exposure to methylmercury, for which hair and blood are credible indicators, urine is the preferred biological medium for the determination of exposure to inorganic mercury, including elemental mercury, with blood normally being of value only if exposure is ongoing. Although treatments are available to help rid the body of mercury in cases of extreme exposure, prevention of exposure will make such treatments unnecessary. Knowing the sources of mercury and avoiding unnecessary exposure are the prudent ways of preventing mercury intoxication. When exposure occurs, it should be kept in mind that not all unwanted exposures will result in adverse health consequences. In all cases, elimination of the source of exposure should be the first priority of public health officials.
ATSDR, Applied Toxicology Branch, Division of Toxicology and Environmental Medicine, Atlanta, GA 30333, USA. jrisher@cdc.gov
John F
JF
Risher
Christopher T
CT
De Rosa
D000931:Antidotes / Q000627:therapeutic use; D015415:Biomarkers; D004781:Environmental Exposure; D004785:Environmental Pollutants / Q000633:toxicity* / Q000652:urine; D006801:Humans; D008628:Mercury / Q000633:toxicity* / Q000652:urine; D008630:Mercury Poisoning / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology; D012307:Risk Factors; D004113:Succimer / Q000627:therapeutic use; D013405:Suicide
D000931:Antidotes; D015415:Biomarkers; D004785:Environmental Pollutants; D004113:Succimer; D008628:Mercury