Organelle motility: running on unleadened.
The study of fish and amphibian melanocytes has yielded a wealth of information on the regulation of microtubule- and actin-based motor proteins involved in organelle transport. A new zebrafish mutant provides further insight into how the actions of these motors are coordinated in vivo.
Laboratory of Cell Biology, Building 50, Room 2523, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland 20892, USA. hammerj@nhlbi.nih.gov
John A
JA
Hammer
Xufeng S
XS
Wu
D000199:Actins / Q000378:metabolism*; D048868:Adaptor Proteins, Signal Transducing; D000818:Animals; D002352:Carrier Proteins / Q000235:genetics / Q000378:metabolism; D008544:Melanocytes / Q000502:physiology; D008547:Melanophores / Q000502:physiology; D020460:Melanosomes / Q000378:metabolism / Q000502:physiology*; D051379:Mice; D008870:Microtubules / Q000378:metabolism*; D020409:Molecular Motor Proteins / Q000378:metabolism*; D015388:Organelles / Q000378:metabolism / Q000502:physiology; D015027:Zebrafish / Q000235:genetics / Q000502:physiology*
D000199:Actins; D048868:Adaptor Proteins, Signal Transducing; D002352:Carrier Proteins; C435724:Mlph protein, mouse; D020409:Molecular Motor Proteins