Decarboxylative reduction of free aliphatic carboxylic acids by photogenerated cation radical.
The decarboxylation of free carboxylic acids was effected by a photogenerated cation radical of phenanthrene to yield the reduction product in the presence of a thiol, which provides an alternative method to the Barton decarboxylation procedure for aliphatic acids such as N-Boc amino acids.
Department of Applied Chemistry and Biotechnology, Graduate School of Engineering, University of Fukui, 3-9-1 Bunkyo, Fukui, Japan. yoshimi@acbio2.acbio.fukui-u.ac.jp
Yasuharu
Y
Yoshimi
Tatsuya
T
Itou
Minoru
M
Hatanaka
D002264:Carboxylic Acids / Q000737:chemistry* / Q000528:radiation effects*; D002412:Cations / Q000737:chemistry / Q000528:radiation effects; D003653:Decarboxylation; D005609:Free Radicals / Q000138:chemical synthesis / Q000737:chemistry / Q000528:radiation effects; D015394:Molecular Structure; D009930:Organic Chemicals / Q000138:chemical synthesis* / Q000737:chemistry / Q000528:radiation effects*; D010084:Oxidation-Reduction; D010777:Photochemistry; D013237:Stereoisomerism; D013438:Sulfhydryl Compounds / Q000737:chemistry; D014466:Ultraviolet Rays
D002264:Carboxylic Acids; D002412:Cations; D005609:Free Radicals; D009930:Organic Chemicals; D013438:Sulfhydryl Compounds