Helicobacter pylori infection: prevalence in chronic urticaria patients and incidence of autoimmune urticaria (study in Dr. Cipto Mangunkusumo Hospital, Jakarta).
OBJECTIVE
To determine the prevalence of Hp infection in patients with chronic urticaria (CU) and to evaluate the result of autologous serum skin test (ASST) in CU patients with Hp infections.


METHODS
In this cross-sectional study, 16 patients with chronic urticaria and 16 non-urticaria volunteers were investigated (matched for age and sex). All subjects were examined for Hp infection with the 13C-urea breath test. Autologous serum skin test was performed in patients with proven Hp infection.


RESULTS
Helicobacter pylori was detected in 12.5% of patients and 0% of the control group. There was no significant difference between the two groups (p = 0.484 using Fisher exact test). Autologous serum skin test was positive in 1 of 2 CU patients with Hp infection.


CONCLUSIONS
In this study, there was no significant difference in the seroprevalence of Hp infection between CU patients and controls. Autologous serum skin test was positive in 1 of 2 CU patients with Hp infection.
Department of Dermatovenereal Disease, Faculty of Medicine, University of Indonesia - Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia.
Grace Nami
GN
Sianturi
Retno W
RW
Soebaryo
Farida
F
Zubier
Ari Fahrial
AF
Syam
D000293:Adolescent; D000328:Adult; D000368:Aged; D001327:Autoimmune Diseases / Q000097:blood / Q000150:complications* / Q000276:immunology; D002908:Chronic Disease; D003430:Cross-Sectional Studies; D004522:Educational Status; D005260:Female; D016481:Helicobacter Infections / Q000097:blood / Q000175:diagnosis / Q000453:epidemiology*; D016480:Helicobacter pylori / Q000302:isolation & purification*; D006801:Humans; D015994:Incidence; D007214:Indonesia / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D016036:Seroepidemiologic Studies; D014581:Urticaria / Q000097:blood / Q000150:complications* / Q000276:immunology