Pain scores and local anesthesia for transrectal ultrasound-guided prostate biopsy in patients with anorectal pathologies.
OBJECTIVE
The aim of the present randomized study was to evaluate the efficacy of lidocaine gel compared with dimethylsulfoxide (DMSO) with lidocaine for transrectal ultrasonography (TRUS)-guided prostate biopsy in patients with anorectal pathologies.


METHODS
Sixty-two patients were randomly divided into two equal groups. Group 1 was given 10 mL of 2% lidocaine gel intrarectally 10 minutes before the biopsy. Group 2 was given 10 mL of intrarectal 40% DMSO with an amount of lidocaine equal to that in the lidocaine gel 10 minutes before the procedure. The degree of pain was rated by patients using a 10-point visual analog scale.


RESULTS
The pain scores for probe insertion were significantly lower for group 2 (3.15 +/- 1.41) than for group 1 (4.58 +/- 160) (P = 0.01). No significant differences were found between the pain scores of the two groups for biopsy-needle insertion (P = 0.62).


CONCLUSIONS
Dimethylsulfoxide with lidocaine instilled into the rectum is a simple, safe, rapid-acting, and effective method of anesthesia delivery before TRUS-guided prostate biopsy in patients with anorectal pathologies.
Department of Urology, Gulhane Military Medical Faculty, Etlik/Ankara, Turkey. demir74@superonline.com
Erkan
E
Demir
Mete
M
Kilicer
Selahattin
S
Bedir
Guldem
G
Kilciler
Koray
K
Erten
Yasar
Y
Ozgok
D000772:Anesthesia, Local / Q000379:methods*; D001706:Biopsy / Q000379:methods; D004121:Dimethyl Sulfoxide; D005782:Gels; D006801:Humans; D008012:Lidocaine / Q000493:pharmacokinetics; D008297:Male; D010147:Pain Measurement; D036761:Ultrasound, High-Intensity Focused, Transrectal / Q000379:methods*
D005782:Gels; D008012:Lidocaine; D004121:Dimethyl Sulfoxide