[Postnatal effects in children irradiated during the intra-uterine development, as a result of failure at the Chernobyl NPP].
Somatic and genetic effects at children who have undergone the influence of ionizing radiation during in utero development and at the subsequent stages ontogenesis are investigated, in view of dozes of the general irradiation and equivalent dozes of an irradiation of red bone brain. 1144 children were examined: 1st group consisted of children who have been born from women pregnant at the moment of failure, evacuated from Pripyat; 2nd group included children who have been born from women pregnant at the moment of failure, stayed to live in a zone of the strict radiation control; 3rd group was the control group--children who have been born in 1986, living in safe region of the Ukraine according to radiation conditions. The presence of direct correlation link between quantity of small anomalies of the development and the total radiation dose of the fetus (R = 0.61, p < 0.002) and inverse link with fetus age at the moment of radiation factor effect (R = -0.53, p < 0.003) has been established. Significant correlation links between the total radiation dose and the level of children health (R = 0.45, p < 0.03); the equivalent radiation dose of the red bone marrow and the frequency of damages in the chromosomal apparatus of the somatic cells (1st group--R = 0.51, p < 0.02; 2nd group--R = 0.62, p < 0.002) have been revealed.
Stepanova
E I
EI
Vdovenko
V Iu
VIu
Misharina
Zh A
ZhA
D047852:Chernobyl Nuclear Accident; D002648:Child; D002657:Child Development / Q000528:radiation effects*; D005260:Female; D005333:Fetus / Q000528:radiation effects*; D006801:Humans; D008297:Male; D018811:Maternal Exposure; D011832:Radiation Injuries / Q000453:epidemiology*; D011839:Radiation, Ionizing; D014455:Ukraine / Q000453:epidemiology