Design and preliminary accuracy studies of an MRI-guided transrectal prostate intervention system.
This paper reports a novel system for magnetic resonance imaging (MRI) guided transrectal prostate interventions, such as needle biopsy, fiducial marker placement, and therapy delivery. The system utilizes a hybrid tracking method, comprised of passive fiducial tracking for initial registration and subsequent incremental motion measurement along the degrees of freedom using fiber-optical encoders and mechanical scales. Targeting accuracy of the system is evaluated in prostate phantom experiments. Achieved targeting accuracy and procedure times were found to compare favorably with existing systems using passive and active tracking methods. Moreover, the portable design of the system using only standard MRI image sequences and minimal custom scanner interfacing allows the system to be easily used on different MRI scanners.
Department of Mechanical Engineering, Johns Hopkins University, Baltimore, USA.
Axel
A
Krieger
Csaba
C
Csoma
Iulian I
II
Iordachital
Peter
P
Guion
Anurag K
AK
Singh
Gabor
G
Fichtinger
Louis L
LL
Whitcomb
D000465:Algorithms; D001185:Artificial Intelligence; D001707:Biopsy, Needle / Q000295:instrumentation* / Q000379:methods; D004867:Equipment Design; D019544:Equipment Failure Analysis; D006801:Humans; D007089:Image Enhancement / Q000295:instrumentation / Q000379:methods; D007090:Image Interpretation, Computer-Assisted / Q000295:instrumentation* / Q000379:methods; D021621:Imaging, Three-Dimensional / Q000295:instrumentation / Q000379:methods; D053783:Magnetic Resonance Imaging, Interventional / Q000295:instrumentation* / Q000379:methods; D008297:Male; D010363:Pattern Recognition, Automated / Q000379:methods; D010865:Pilot Projects; D011468:Prostatectomy / Q000379:methods*; D011471:Prostatic Neoplasms / Q000473:pathology* / Q000601:surgery*; D012007:Rectum / Q000473:pathology / Q000601:surgery; D015203:Reproducibility of Results; D012371:Robotics / Q000295:instrumentation* / Q000379:methods; D012680:Sensitivity and Specificity; D014584:User-Computer Interface