[Orthotopic liver transplantation: results at a single center].
BACKGROUND
We undertook this study to describe the results of hepatic orthotopic transplant. Patient characteristics, implants, and patient evolution after transplant were studied. The study was conducted at a third-level medical facility in Mexico.


METHODS
The files of 49 patients who had a liver transplant were reviewed from July 17, 1999, through November 30, 2006. We also analyzed pretransplant status and status of the hepatic implant at the time of the transplant. Finally, patient evolution was reported postoperatively.


RESULTS
Fifty transplants were carried out in 49 patients (one man was retransplanted and one women had a liver and kidney transplant). There were 35 women (71.43%) and 14 men (28.57%). Ages of the patients were between 2 and 61 years (average 40.40 years). The most frequent causes resulting in transplants were cirrhosis caused by hepatitis C virus (HCV) and autoimmune cirrhosis: 28 cases (56%) and 7 cases (14%), respectively. Four patients (8%) died from surgery-related complications and 11 patients died (22%) from nonsurgical complications. Patient survival according to Child-Pugh is as follows: Child-Pugh A: 3/4 patients (75%), Child-Pugh B: 17/24 patients (70%), Child-Pugh C: 15/22 patients (68%). Preoperative survival was 35 patients (70%), 1-year survival was 32 patients (64) and 5-year survival was 29 patients (58%).


CONCLUSIONS
Survival rates of our patients are acceptable even though the majority of those transplanted had severe hepatic insufficiency and others had diabetes and portal thrombosis.
Unidad de Trasplantes, Hospital des Especialidades, Centro Médico Nacional de Occidente, Instituto Mexicano del Seguro Social, Guadalajara, Jalisco. Av. Cubilete 212, Col. Chapalita, 45050 Zapopan, Jalisco, Mexico. fmstransplant@hotmail.com
Federico
F
Mendoza-Sánchez
Francisco Javier
FJ
Haro-Haro
Jesús
J
Sandoval-Alvarado
Alonso
A
Zepeda-González
Roberto
R
Herrera-Rodríguez
Angel
A
Bassols-Ricardez
D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008107:Liver Diseases / Q000601:surgery*; D016031:Liver Transplantation / Q000379:methods; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies