Conjunctival intraepithelial neoplasia in a patient treated with tacrolimus after liver transplantation.
OBJECTIVE
To report a case of conjunctival intraepithelial neoplasia in a patient treated with tacrolimus after liver transplantation for hepatic carcinoma.


METHODS
Description of the initial clinical presentation of a patient, tumor management, and 15-month follow-up.


RESULTS
A 70-year-old man presented with a conjunctival intraepithelial neoplasia that developed on the site of a preexisting pterygium. After total surgical removal and additional application of mitomycin, local tumor control was achieved.


CONCLUSIONS
We describe a case of intraepithelial conjunctival neoplasia in a patient treated with systemic tacrolimus. Local tumor control was achieved at 15 months after appropriate surgical management.
Jules Gonin Eye Hospital, University of Lausanne, Lausanne, Switzerland.
Jean-Antoine C
JA
Pournaras
Line
L
Chamot
Sylvie
S
Uffer
Leonidas
L
Zografos
D000368:Aged; D000903:Antibiotics, Antineoplastic / Q000627:therapeutic use; D002278:Carcinoma in Situ / Q000188:drug therapy / Q000209:etiology* / Q000601:surgery; D003131:Combined Modality Therapy; D003230:Conjunctival Neoplasms / Q000188:drug therapy / Q000209:etiology* / Q000601:surgery; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D008113:Liver Neoplasms / Q000188:drug therapy; D016031:Liver Transplantation; D008297:Male; D016685:Mitomycin / Q000627:therapeutic use; D016559:Tacrolimus / Q000627:therapeutic use*
D000903:Antibiotics, Antineoplastic; D007166:Immunosuppressive Agents; D016685:Mitomycin; D016559:Tacrolimus