Change in the accommodative force on the lens of the human eye with age.
The aim of the study was to determine the age-dependence of the accommodative force on the lens in order to make it clear whether the causes of presbyopia are due to lenticular or extralenticular changes. A finite element model of the lens of an 11-, 29- and 45-year-old human eye was constructed to represent the fully accommodated state. Subsequently, the force that was needed to mould the lens into its unaccommodated state was calculated. The force on the lens appeared to be preserved with age, with only a slight increase to a value of approximately 0.06N. In conclusion, the preservation of the net force delivered by the extralenticular ciliary body indicates that the causes of presbyopia must be ascribed to lenticular changes.
Hermans
E A
EA
Department of Physics and Medical Technology, VU University Medical Center, P.O. Box 7057, 1007 MB Amsterdam, The Netherlands. ea.hermans@vumc.enl
Dubbelman
M
M
van der Heijde
G L
GL
Heethaar
R M
RM
D000065:Accommodation, Ocular / Q000502:physiology*; D000328:Adult; D000375:Aging / Q000502:physiology*; D002648:Child; D002924:Ciliary Body / Q000502:physiology; D020342:Finite Element Analysis; D006801:Humans; D007908:Lens, Crystalline / Q000033:anatomy & histology / Q000502:physiology*; D008875:Middle Aged; D008954:Models, Biological; D011305:Presbyopia / Q000503:physiopathology; D013314:Stress, Mechanical