Pulp revascularization of a necrotic infected immature permanent tooth: case report and review of the literature.
The purpose of this report was to present the case of a patient wherein revascularization of the necrotic infected pulp space of an immature permanent maxillary central incisor tooth was induced in vivo by stimulation of a blood clot from the periapical tissues into the canal space. This was achieved after disinfection of the canal space with a topical antibiotic paste followed by a blood clot scaffold induced from the periapical tissues. This treatment approach offers clinicians great potential to avoid the need for traditional apexification with calcium hydroxide or the need to achieve an artificial apical barrier with mineral trioxide aggregate. Furthermore, this treatment approach can help rescue infected immature teeth by physiologically strengthening the root walls.
Thibodeau
Blayne
B
Department of Endodontics, University of North Carolina, Chapel Hill, NC, USA. blaynethibodeau@gmail.com
Trope
Martin
M
D017607:Aluminum Compounds / Q000627:therapeutic use; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000890:Anti-Infective Agents / Q000627:therapeutic use; D001777:Blood Coagulation / Q000502:physiology; D017610:Calcium Compounds / Q000627:therapeutic use; D002433:Cefaclor / Q000627:therapeutic use; D002648:Child; D003782:Dental Pulp / Q000098:blood supply* / Q000503:physiopathology; D003786:Dental Pulp Cavity / Q000503:physiopathology; D003790:Dental Pulp Necrosis / Q000628:therapy*; D004202:Disinfectants / Q000627:therapeutic use; D004203:Disinfection / Q000379:methods; D004338:Drug Combinations; D005500:Follow-Up Studies; D006801:Humans; D007180:Incisor / Q000503:physiopathology*; D008297:Male; D008795:Metronidazole / Q000627:therapeutic use; D009805:Odontogenesis / Q000502:physiology*; D010087:Oxides / Q000627:therapeutic use; D010486:Periapical Tissue / Q000503:physiopathology; D011206:Povidone-Iodine / Q000627:therapeutic use; D012387:Root Canal Filling Materials / Q000627:therapeutic use; D017640:Silicates / Q000627:therapeutic use; D012973:Sodium Hypochlorite / Q000627:therapeutic use; D019227:Tooth Apex / Q000503:physiopathology
D017607:Aluminum Compounds; D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D017610:Calcium Compounds; D004202:Disinfectants; D004338:Drug Combinations; D010087:Oxides; D012387:Root Canal Filling Materials; D017640:Silicates; C086631:mineral trioxide aggregate; D008795:Metronidazole; D002433:Cefaclor; D011206:Povidone-Iodine; D012973:Sodium Hypochlorite