The socioeconomic determinants of HIV incidence: evidence from a longitudinal, population-based study in rural South Africa.
BACKGROUND
Knowledge of the effect of socioeconomic status on HIV infection in Africa stems largely from cross-sectional studies. Cross-sectional studies suffer from two important limitations: two-way causality between socioeconomic status and HIV serostatus and simultaneous effects of socioeconomic status on HIV incidence and HIV-positive survival time. Both problems are avoided in longitudinal cohort studies.


METHODS
We used data from a longitudinal HIV surveillance and a linked demographic surveillance in a poor rural community in KwaZulu-Natal, South Africa, to investigate the effect of three measures of socioeconomic status on HIV incidence: educational attainment, household wealth categories (based on a ranking of households on an assets index scale) and per capita household expenditure. Our sample comprised of 3325 individuals who tested HIV-negative at baseline and either HIV-negative or -positive on a second test (on average 1.3 years later).


RESULTS
In multivariable survival analysis, one additional year of education reduced the hazard of acquiring HIV by 7% (P = 0.017) net of sex, age, wealth, household expenditure, rural vs. urban/periurban residence, migration status and partnership status. Holding other factors equal, members of households that fell into the middle 40% of relative wealth had a 72% higher hazard of HIV acquisition than members of the 40% poorest households (P = 0.012). Per capita household expenditure did not significantly affect HIV incidence (P = 0.669).


CONCLUSIONS
Although poverty reduction is important for obvious reasons, it may not be as effective as anticipated in reducing the spread of HIV in rural South Africa. In contrast, our results suggest that increasing educational attainment in the general population may lower HIV incidence.
Africa Centre for Health and Population Studies, University of KwaZulu-Natal, Mtubatuba, South Africa. tbarnighausen@africacentre.ac.za
Till
T
Bärnighausen
Victoria
V
Hosegood
Ian M
IM
Timaeus
Marie-Louise
ML
Newell
D000293:Adolescent; D000328:Adult; D004522:Educational Status; D005191:Family Characteristics; D005260:Female; D015658:HIV Infections / Q000453:epidemiology* / Q000401:mortality; D015497:HIV-1; D006801:Humans; D015994:Incidence; D008137:Longitudinal Studies; D008297:Male; D011159:Population Surveillance; D011203:Poverty; D012423:Rural Health; D012725:Sexual Behavior; D012959:Socioeconomic Factors; D013019:South Africa / Q000453:epidemiology