Synthesis of new L-ascorbic ferulic acid hybrids.
A feasibility and chemical study of the coupling conditions of L-ascorbic acid with ferulic acid derivatives are described on the basis of the known synergistic effects of mixtures of various antioxidants. Novel L-ascorbic ferulic hybrids linked at the C-3 hydroxyl group were prepared with the aim to protect the alcohol function and the enediol system.
Voisin-Chiret
Anne Sophie
AS
Université de Caen Basse-Normandie, U.F.R. des Sciences Pharmaceutiques, Centre d'Etudes et de Recherche sur le Médicament de Normandie, UPRES EA-3915, 5, rue Vaubénard, 14032 CAEN Cedex, France.
Bazin
Marc-Antoine
MA
Lancelot
Jean-Charles
JC
Rault
Sylvain
S
D000975:Antioxidants / Q000138:chemical synthesis / Q000737:chemistry; D001205:Ascorbic Acid / Q000138:chemical synthesis / Q000737:chemistry; D003373:Coumaric Acids / Q000138:chemical synthesis / Q000737:chemistry; D006801:Humans; D015394:Molecular Structure; D016877:Oxidants / Q000737:chemistry; D018384:Oxidative Stress
D000975:Antioxidants; D003373:Coumaric Acids; D016877:Oxidants; C004999:ferulic acid; D001205:Ascorbic Acid