Picosecond infrared probing of the vibrational spectra of transients formed upon UV excitation of stacked G-tetrad structures.
The photophysical properties of stacked G-tetrads in diverse systems, including concentrated solutions of 5'-guanosine monophosphate (5'-GMP), polyguanylic acid (poly(G)) and the G-rich oligodeoxynucleotide sequence characteristic of human telomeric DNA, are probed by ps-TRIR and compared to those of the monomeric 5'-GMP.
School of Chemistry and Centre for Chemical Synthesis and Chemical Biology, Trinity College, Dublin 2, Ireland.
David A
DA
McGovern
Susan
S
Quinn
Gerard W
GW
Doorley
Aine M
AM
Whelan
Kate L
KL
Ronayne
Michael
M
Towrie
Anthony W
AW
Parker
John M
JM
Kelly
D004247:DNA / Q000737:chemistry / Q000528:radiation effects; D006157:Guanosine Monophosphate / Q000737:chemistry / Q000528:radiation effects; D006801:Humans; D006860:Hydrogen Bonding; D015394:Molecular Structure; D009838:Oligodeoxyribonucleotides / Q000737:chemistry / Q000528:radiation effects; D010710:Phosphates / Q000737:chemistry / Q000528:radiation effects; D011068:Poly G / Q000737:chemistry / Q000528:radiation effects; D013055:Spectrophotometry, Infrared / Q000379:methods; D016615:Telomere / Q000737:chemistry / Q000528:radiation effects; D013997:Time Factors; D014466:Ultraviolet Rays; D014732:Vibration
D009838:Oligodeoxyribonucleotides; D010710:Phosphates; D011068:Poly G; D006157:Guanosine Monophosphate; D004247:DNA