[A comparative clinical study of the treatment of hypertrophic scars with either intralaesional steroid or silicone gel sheeting].
The linear (or "surgical") hypertrophic scar is the most common type of pathologic scarring. There has been a steady increase in the number of patients with hypertrophic scars over the years due to the rising number of operative interventions altogether. However, the therapeutic protocols are not homogeneous and they show significant variations. 200 cases with hypertrophic scars were treated by the authors from April 2001 to March 2004. 24 patients were selected in the study from these cases; and two randomized groups were formed. Each group included 12-12 patients, who were treated with either intralaesional steroid or silicone gel sheeting. The therapeutic protocols were defined by the authors. The aim of this study was to compare and determine the roles of these two commonly used treatment options of hypertrophic scars. The authors present patient demographics; and analyze the results and outcome of the study. Both methods were efficient significantly, however intralaesional steroid therapy had a more rapid effect and it lasted longer than silicone gel sheeting. These results confirmed the role of these two treatment modalities in the protocols. The authors concluded that silicone gel sheeting is the first line, while intralaesional steroid is the second line treatment for primary linear hypertrophic scars. Based on the authors' experience, in recurrent linear hypertrophic scars, intralaesional steroid therapy is recommended in first line, because silicone gel sheeting was largely ineffective. Prospective randomized clinical trials should be needed to further clarify their role in the treatment protocols.
Kelemen
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Baranya Megyei Kórház - Pécsi Tudományegyetem, Altalános Orvostudományi Kar, OEC, Sebészeti Tanszék 7623 Pécs. okelemen@t-online.hu
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D000293:Adolescent; D000328:Adult; D000368:Aged; D001458:Bandages; D017439:Cicatrix, Hypertrophic / Q000188:drug therapy / Q000209:etiology / Q000628:therapy*; D005260:Female; D005938:Glucocorticoids / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D015552:Injections, Intralesional; D008297:Male; D016462:Mammaplasty / Q000009:adverse effects; D008875:Middle Aged; D020034:Silicone Gels / Q000627:therapeutic use*; D013934:Thymectomy / Q000009:adverse effects; D016896:Treatment Outcome; D014221:Triamcinolone / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000627:therapeutic use
D005938:Glucocorticoids; D020034:Silicone Gels; D014221:Triamcinolone; C030262:triamcinolone diacetate