Coating bone-like apatite onto organic substrates using solutions mimicking body fluid.
Bone-like apatite is a carbonated hydroxyapatite with a small crystallite and low crystallinity. The formation of a layer consisting of bone-like apatite is an essential condition for bioactive materials to achieve direct bonding with living bone. A bone-like apatite layer can be formed on the surface of organic substrates in a solution mimicking a body fluid when some functional groups are introduced to organic substrates. This process is a biomimetic process because a simulated body fluid and related solutions are used to deposit bone-like apatite crystals and promote crystal growth. Coating of bone-like apatite layers through biomimetic processes has received much attention in the fabrication of novel composites with bone-bonding properties, i.e. bioactivity, and mechanical properties analogous to those of living bone tissues. This paper reviews recent developments in coating with bone-like apatite layers using biomimetic processes.
Department of Crystalline Materials Science, Graduate School of Engineering, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8603, Japan.
Chikara
C
Ohtsuki
Masanobu
M
Kamitakahara
Toshiki
T
Miyazaki
D001672:Biocompatible Materials / Q000737:chemistry*; D040761:Biomimetic Materials / Q000737:chemistry*; D001826:Body Fluids; D017886:Durapatite / Q000737:chemistry*; D006801:Humans; D009930:Organic Chemicals / Q000737:chemistry*; D012996:Solutions
D001672:Biocompatible Materials; D009930:Organic Chemicals; D012996:Solutions; D017886:Durapatite