[Female patient with organic psychosyndrome and neurological focal signs after immunosuppressant therapy].
Cerebral toxoplasmosis nearly exclusively affects immunodeficient or immunocompromised patients. Mostly, it is a reactivation of latent toxoplasmosis. The pathogens, persisting in the reticuloendothelial system of heart and skeletal muscle cells, are causing a multifocal necrotizing encephalitis. The characteristic clinical features are organic psychosyndrome and focal neurological signs such as monoparesis, hemiparesis, aphasia, or seizures. Here we describe a 56-years-old patient who developed cerebral toxoplasmosis after receiving stem-cell transplantation treatment for acute myeloic leukemia, and we discuss the clinical features, differential diagnoses and therapeutic strategies.
Kühnlein
P
P
Neurologische Klinik der Universität Ulm, Rehabilitationskrankenhaus Ulm, Am Oberen Eselsberg 45, 89081, Ulm, Deutschland. peter.kuehnlein@uni-ulm.de
Ringhoffer
M
M
Tumani
H
H
Gdynia
H J
HJ
D005260:Female; D018380:Hematopoietic Stem Cell Transplantation / Q000009:adverse effects*; D006801:Humans; D007165:Immunosuppression Therapy / Q000009:adverse effects*; D008875:Middle Aged; D011602:Psychophysiologic Disorders / Q000175:diagnosis* / Q000209:etiology* / Q000628:therapy; D016781:Toxoplasmosis, Cerebral / Q000175:diagnosis* / Q000209:etiology* / Q000628:therapy; D016896:Treatment Outcome