McCune-Albright syndrome associated with acromegaly and bipolar affective disorder.
McCune-Albright syndrome is a rare disorder caused by an activating mutation in the gene (GNAS1) encoding the subunit of the G protein. This syndrome is characterized by polyostotic fibrous dysplasia, café-au-lait pigmentation, and multiple endocrine hyperfunction. A 29-year-old male with polyostotic fibrous dysplasia, café-au-lait pigmentations, and pituitary adenoma is presented in this report. The patient had accompanying bipolar affective disorder, which might have been caused by the underlying genetic abnormality.
Hacettepe University, Hacettepe Medical School, Department of Nuclear Medicine, 06100-Sihhiye, Ankara, Turkey.
Pelin
P
Ozcan-Kara
Babek
B
Mahmoudian
Belkis
B
Erbas
Tomris
T
Erbas