[Renal involvement by AA amyloidosis in inclusion body myositis].
Inclusion body myositis is currently considered a variant of adult inflammatory myopathies. Clinical course is insidious and besides typical proximal muscles disorder, extension to distal ones is found in up to 95% of cases. Mean survival ranges from 3 to 5 years. Infections are the first death cause, secondary to existing disability a few years after diagnosis. Chronic rheumatic diseases related amyloidosis has became the most frequent kind of reactive amyloidosis or AA amyloidosis. Clinical manifestations of AA amyloidosis mainly affect the kidney. We present the case of a woman with Inclusion body myositis and renal involvement by AA amyloidosis. In our review of literature we haven t found any article relating AA amyloidosis with idiopathic inflammatory myopathies of the adult, what would turn this case into the first ever reported. We can probably find the reason in the bad prognosis of this entity. So we propose making a renal biopsy to all those patients with a long lasting rheumatologic disease and unexpected impaired renal function.
Díaz Rodríguez
C
C
Servicio de Nefroloía, F.P Hospital Virxe da Xunqueira, España. candido.diaz.rodriguez@sergas.es
Moreno Fernández
A
A
Sacristán
F
F
D000368:Aged; D000686:Amyloidosis / Q000209:etiology*; D005260:Female; D006801:Humans; D007674:Kidney Diseases / Q000209:etiology*; D018979:Myositis, Inclusion Body / Q000150:complications*