Stereoselective synthesis of 1'-functionalized-4'-thionucleosides.
Stereoselective functionalization of the 1'-position of 4'-thionucleosides was achieved using a stereoselective S(N)2 reaction controlled by 5-membered ring coordination.
College of Pharmacy, Ewha Womans University, Seoul, Korea. lakjeong@ewha.ac.kr
Lak Shin
LS
Jeong
Prashantha
P
Gunaga
Hea Ok
HO
Kim
Dilip K
DK
Tosh
Hyuk Woo
HW
Lee
Seung Ah
SA
Choe
Hyung Ryong
HR
Moon
Zhan-Guo
ZG
Gao
Kenneth A
KA
Jacobson
Moon Woo
MW
Chun
D058918:Adenosine A3 Receptor Antagonists; D015195:Drug Design; D006801:Humans; D006860:Hydrogen Bonding; D013237:Stereoisomerism; D013872:Thionucleosides / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology
D058918:Adenosine A3 Receptor Antagonists; D013872:Thionucleosides