Organelle motility: running on unleadened.
The study of fish and amphibian melanocytes has yielded a wealth of information on the regulation of microtubule- and actin-based motor proteins involved in organelle transport. A new zebrafish mutant provides further insight into how the actions of these motors are coordinated in vivo.
Hammer
John A
JA
Laboratory of Cell Biology, Building 50, Room 2523, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland 20892, USA. hammerj@nhlbi.nih.gov
Wu
Xufeng S
XS
D000199:Actins / Q000378:metabolism*; D048868:Adaptor Proteins, Signal Transducing; D000818:Animals; D002352:Carrier Proteins / Q000235:genetics / Q000378:metabolism; D008544:Melanocytes / Q000502:physiology; D008547:Melanophores / Q000502:physiology; D020460:Melanosomes / Q000378:metabolism / Q000502:physiology*; D051379:Mice; D008870:Microtubules / Q000378:metabolism*; D020409:Molecular Motor Proteins / Q000378:metabolism*; D015388:Organelles / Q000378:metabolism / Q000502:physiology; D015027:Zebrafish / Q000235:genetics / Q000502:physiology*
D000199:Actins; D048868:Adaptor Proteins, Signal Transducing; D002352:Carrier Proteins; C435724:Mlph protein, mouse; D020409:Molecular Motor Proteins