Head-to-tail cyclized cystine-knot peptides by a combined recombinant and chemical route of synthesis.
Institut für Organische Chemie und Biochemie, TU Darmstadt, Petersenstrasse 22, 64287 Darmstadt, Germany.
Olga
O
Avrutina
Hans-Ulrich
HU
Schmoldt
Dusica
D
Gabrijelcic-Geiger
Alexander
A
Wentzel
Holm
H
Frauendorf
Christian P
CP
Sommerhoff
Ulf
U
Diederichsen
Harald
H
Kolmar
D000595:Amino Acid Sequence; D001426:Bacterial Proteins; D002851:Chromatography, High Pressure Liquid; D003500:Cyclization; D047168:Cystine Knot Motifs; D004220:Disulfides / Q000737:chemistry; D053804:Granzymes / Q000037:antagonists & inhibitors / Q000378:metabolism; D006801:Humans; D006835:Hydrazones / Q000737:chemistry; D008958:Models, Molecular; D008969:Molecular Sequence Data; D010084:Oxidation-Reduction; D010456:Peptides, Cyclic / Q000096:biosynthesis* / Q000138:chemical synthesis* / Q000235:genetics; D010504:Periodic Acid / Q000737:chemistry; D017510:Protein Folding; D011993:Recombinant Fusion Proteins / Q000096:biosynthesis / Q000737:chemistry / Q000235:genetics / Q000378:metabolism; D012260:Ribonucleases / Q000235:genetics / Q000378:metabolism
D001426:Bacterial Proteins; D004220:Disulfides; D006835:Hydrazones; C519458:McoEeTI protein; D010456:Peptides, Cyclic; D011993:Recombinant Fusion Proteins; D010504:Periodic Acid; C009288:metaperiodate; D012260:Ribonucleases; C019760:Bacillus amyloliquefaciens ribonuclease; C088546:GZMK protein, human; D053804:Granzymes