The effects of nutritional supplementation throughout an endurance run on leucine kinetics during recovery.
This study determined the effect of nutritional supplementation throughout endurance exercise on whole-body leucine kinetics (leucine rate of appearance [Ra], oxidation [Ox], and nonoxidative leucine disposal [NOLD]) during recovery. Five trained men underwent a 2-h run at 65% VO(2max), during which a carbohydrate (CHO), mixed protein-carbohydrate (milk), or placebo (PLA) drink was consumed. Leucine kinetics were assessed during recovery using a primed, continuous infusion of 1-13C leucine. Leucine Ra and NOLD were lower for milk than for PLA. Ox was higher after milk-supplemented exercise than after CHO or PLA. Although consuming milk during the run affected whole-body leucine kinetics, the benefits of such a practice for athletes remain unclear. Additional studies are needed to determine whether protein supplementation during exercise can optimize protein utilization during recovery.
Miller
Sharon L
SL
Department of Nutritional Sciences, University of Connecticut, Storrs, CT 06269, USA.
Gaine
P Courtney
PC
Maresh
Carl M
CM
Armstrong
Lawrence E
LE
Ebbeling
Cara B
CB
Lamont
Linda S
LS
Rodriguez
Nancy R
NR
D000293:Adolescent; D000328:Adult; D000818:Animals; D002247:Carbon Isotopes; D018592:Cross-Over Studies; D004040:Dietary Carbohydrates / Q000378:metabolism / Q000494:pharmacology*; D004044:Dietary Proteins / Q000378:metabolism / Q000494:pharmacology*; D019587:Dietary Supplements; D004734:Energy Metabolism; D006801:Humans; D007930:Leucine / Q000493:pharmacokinetics*; D008297:Male; D008892:Milk; D010101:Oxygen Consumption; D010807:Physical Endurance / Q000502:physiology*
D002247:Carbon Isotopes; D004040:Dietary Carbohydrates; D004044:Dietary Proteins; D007930:Leucine