Finsler tractography for white matter connectivity analysis of the cingulum bundle.
In this paper, we present a novel approach for the segmentation of white matter tracts based on Finsler active contours. This technique provides an optimal measure of connectivity, explicitly segments the connecting fiber bundle, and is equipped with a metric which is able to utilize the directional information of high angular resolution data. We demonstrate the effectiveness of the algorithm for segmenting the cingulum bundle.
Department of Electrical and Computer Engineering, Georgia Institute of Technology, USA. jmelonak@ece.gatech.edu
John
J
Melonakos
Vandana
V
Mohan
Marc
M
Niethammer
Kate
K
Smith
Marek
M
Kubicki
Allen
A
Tannenbaum
D000465:Algorithms; D001185:Artificial Intelligence; D038524:Diffusion Magnetic Resonance Imaging / Q000379:methods*; D006179:Gyrus Cinguli / Q000033:anatomy & histology*; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D021621:Imaging, Three-Dimensional / Q000379:methods*; D009413:Nerve Fibers, Myelinated / Q000648:ultrastructure*; D009434:Neural Pathways / Q000033:anatomy & histology*; D010363:Pattern Recognition, Automated / Q000379:methods*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity