Neonatal gastrointestinal mucormycosis--a case report.
Mucormycosis is a rare opportunistic fungal infection. It occurs mainly in immunocompromised patients and is usually fatal in children. This fungus can affect central nervous system, nasopharynx, lungs, skin and gastrointestinal tract. It invades the blood vessels and causes thrombosis, leading to infarction of the surrounding tissues. The diagnosis depends mainly on histopathological examination and demonstration of the fungus in the tissue sections, therefore a high index of suspicion and early exploration is required. We report a case of malnourished child who presented with perforation peritonitis. Investigations revealed very low total serum proteins and raised serum creatinine and blood urea levels. On exploratory laparotomy three perforations were located in the gastrointestinal tract. Histopathlogical examination of the perforation edge sections showed characteristic fungal hyphae confirming the diagnosis of gastrointestinal mucormycosis.
Department of Pathology, Lady Hardinge Medical College, New Delhi.
Monisha
M
Choudhury
Eram
E
Kahkashan
Subhasish Roy
SR
Choudhury
D017809:Fatal Outcome; D006801:Humans; D007223:Infant; D007416:Intestinal Perforation / Q000382:microbiology* / Q000473:pathology / Q000601:surgery; D008297:Male; D009091:Mucormycosis / Q000150:complications* / Q000473:pathology; D011502:Protein-Energy Malnutrition / Q000150:complications; D013272:Stomach Diseases / Q000382:microbiology* / Q000601:surgery