Unusual presentation of metastatic hepatocellular carcinoma in the nasal septum: a case report and review of the literature.
Hepatocellular carcinoma with sinonasal metastasis is extremely rare. We report a case of a 49-year-old man who had a history of synchronous hepatocellular carcinoma and verrucous carcinoma of tongue. A painless and non-bleeding mass was found in the left nasal septum 16 months after hepatocellular carcinoma was diagnosed. On computed tomography, the mass was enhanced with contrast. It was resected and proved to be metastatic hepatocellular carcinoma. The patient was treated with radiotherapy to the nasal area and then with chemotherapy. He was still alive, 15 months after the appearance of the nasal metastasis.
Division of Gastroenterology, Department of Internal Medicine, Mackay Memorial Hospital, Mackay Medicine, Nursing and Management College, No. 92, Sec. 2, Chung Shan North Road, Taipei, Taiwan.
Ching-Wei
CW
Chang
Tsang-En
TE
Wang
Li-Tzong
LT
Chen
Wen-Hsiung
WH
Chang
Yi-Shing
YS
Leu
Yang-Kai
YK
Fan
Yu-Jan
YJ
Chan
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000970:Antineoplastic Agents / Q000627:therapeutic use; D006528:Carcinoma, Hepatocellular / Q000556:secondary* / Q000628:therapy; D018289:Carcinoma, Verrucous / Q000601:surgery; D006801:Humans; D008113:Liver Neoplasms / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009300:Nasal Septum / Q000473:pathology; D009669:Nose Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary* / Q000628:therapy; D018714:Radiotherapy, Adjuvant; D014057:Tomography, X-Ray Computed; D000509:alpha-Fetoproteins / Q000032:analysis
D000970:Antineoplastic Agents; D000509:alpha-Fetoproteins