Granulomatous nephritis and meningoencephalomyelitis caused by Halicephalobus gingivalis in a pony gelding.
A ten-year-old Shetland pony gelding showed low appetite, ataxia, peculiar swaying, clouding of consciousness, and ultimately died. At necropsy, multiple coalescing granulomatous foci were detected in the kidneys, and small necrotic lesions were found in the cerebellum. Histologic examination of the renal tissue sections revealed extensive granuloma, and Halicephalobus gingivalis-like nematodes were seen. Similar nematodes were found in the granulomatous or necrotic lesions of the renal lymph nodes and cerebellum, and were also frequently detected in cerebrospinal meningovascular lesions. Morphologic features together with partial ribosomal RNA gene sequences of the nematodes in the lesions revealed that they were H. gingivalis. The present results indicated that H. gingivalis caused granulomatous nephritis and meningoencephalomyelitis in this pony gelding.
Kenhoku Livestock Hygiene Service Center, Ibaraki Prefecture, 966-1 Nakagachi, Mito, Ibaraki 310-0002, Japan.
Masataka
M
Akagami
Tomoyuki
T
Shibahara
Toyoshi
T
Yoshiga
Nobuaki
N
Tanaka
Yuji
Y
Yaguchi
Tokio
T
Onuki
Takashi
T
Kondo
Takashi
T
Yamanaka
Masanori
M
Kubo
D000818:Animals; D006099:Granuloma / Q000469:parasitology / Q000473:pathology / Q000662:veterinary*; D006734:Horse Diseases / Q000469:parasitology* / Q000473:pathology; D006736:Horses; D008297:Male; D008590:Meningoencephalitis / Q000469:parasitology / Q000473:pathology / Q000662:veterinary*; D009348:Nematoda / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*; D009349:Nematode Infections / Q000150:complications / Q000469:parasitology / Q000662:veterinary*; D009393:Nephritis / Q000469:parasitology / Q000473:pathology / Q000662:veterinary*; D010802:Phylogeny