[Association between hip fractures and risk factors for osteoporosis. Multivariate analysis].
In this observational, case-control study, 376 inpatients were evaluated in order to determine the association of risk factors (RF) and hip fracture; 151 patients had osteoporotic hip fracture (cases); the remaining were controls. Data were obtained from medical charts, and through a standardized questionnaire about RF. Mean age of the sample (+/- SD) was 80.6 +/- 8.1 years, without statistically significant difference between cases and controls; the female:male ratio was 3:1 in both groups. Fractured women were older than men (82.5 +/- 8.1 vs. 79.7 +/- 7.2 years, respectively; p < 0.01). Physical activity, intake of alcohol and tobacco, and sun exposure were low in all patients. Falls among cases happened predominantly at home (p < 0.001). Among female cases, time spent in household duties was a RF (p = 0.007), which was absent in males. In multivariate analysis, the following RF were significantly more frequent: Cognitive impairment (p = 0.001), and previous falls (p < 0.0001); whereas the following protective factors were significantly different from controls: Calcium intake during youth (p < 0.0001), current calcium intake (p < 0.0001), and mechanical aid for walking (p < 0.0001). Evaluation of RF and protective factors may contribute to diminish the probability of hip fracture, through a modification of personal habits, and measures to prevent falls among elderly adults. Present information can help to develop local and national population-based strategies to diminish the burden of hip fractures for the health system.
Cátedra de Química Biológica, Facultad de Ciencias Médicas, Universidad Nacional de Rosario y Centro para el Estudio del Climaterio, Hospital Provincial del Centenario.
Ana
A
Masoni
Mario
M
Morosano
María Florencia
MF
Tomat
Stella M
SM
Pezzotto
Ariel
A
Sánchez
D000058:Accidental Falls / Q000706:statistics & numerical data*; D000203:Activities of Daily Living; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D000428:Alcohol Drinking / Q000009:adverse effects; D001118:Argentina / Q000453:epidemiology; D015519:Bone Density / Q000502:physiology; D004812:Epidemiologic Methods; D005260:Female; D015577:Geriatric Assessment; D006620:Hip Fractures / Q000453:epidemiology* / Q000209:etiology / Q000517:prevention & control; D006801:Humans; D008297:Male; D010024:Osteoporosis / Q000150:complications*; D012907:Smoking / Q000009:adverse effects