Factors influencing the efficacy of virtual reality distraction analgesia during postburn physical therapy: preliminary results from 3 ongoing studies.
OBJECTIVE
To assess the efficacy and side effects of immersive virtual reality (VR) distraction analgesia, as well as patient factors associated with VR analgesic efficacy in burn patients who require passive range-of-motion (ROM) physical therapy (PT).


METHODS
Prospective, randomized, controlled, within-subject trials.


METHODS
Regional level I burn center in a university-affiliated urban hospital.


METHODS
Patients (age range, 6-65y) who required passive ROM PT in sessions lasting 3 to 15 minutes after cutaneous burn injury.


METHODS
Standard analgesic (opioid and/or benzodiazepine) care and standard analgesic care plus immersive VR distraction.


METHODS
Self-reported subjective pain ratings (0 to 100 graphic rating scale).


RESULTS
A total of 146 treatment comparisons were made in 88 subjects, 75% of whom were children ages 6 to 18 years. Compared with standard analgesic treatment alone, the addition of VR distraction resulted in significant reductions in subjective pain ratings for worst pain intensity (20% reduction), pain unpleasantness (26% reduction), and time spent thinking about pain (37% reduction). Subjects' age, sex, ethnicity, size of initial burn injury, or duration of therapy session did not affect the analgesic effects of VR distraction. Nausea with the standard care plus VR distraction condition was infrequent (15%) and mild, with 85% of the subjects reporting no nausea. Children provided higher subjective reports of "presence" in the virtual environment and "realness" of the virtual environment than did adults, but age did not affect the analgesic effects of VR distraction.


CONCLUSIONS
When added to standard analgesic therapy, VR distraction provides a clinically meaningful degree of pain relief to burn patients undergoing passive ROM PT. Multiple patient factors do not appear to affect the analgesic effect. Immersive VR distraction is a safe and effective nonpharmacologic technique with which to provide adjunctive analgesia to facilitate patient participation in rehabilitation activities.
Department of Anesthesiology, University of Washington, Seattle, WA, USA. sharar@u.washington.edu
Sam R
SR
Sharar
Gretchen J
GJ
Carrougher
Dana
D
Nakamura
Hunter G
HG
Hoffman
David K
DK
Blough
David R
DR
Patterson
D000293:Adolescent; D000328:Adult; D000698:Analgesia; D000701:Analgesics, Opioid; D001569:Benzodiazepines; D002053:Burn Units; D002056:Burns / Q000534:rehabilitation*; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010147:Pain Measurement / Q000145:classification* / Q000523:psychology; D026741:Physical Therapy Modalities
D000701:Analgesics, Opioid; D001569:Benzodiazepines