Breast cancer among Hispanic and non-Hispanic White women in Arizona.
BACKGROUND
Breast cancer in Hispanic women is poorly understood and data on tumor hormone receptor status in this population are limited.


METHODS
Using data from the Arizona Cancer Registry, we assessed differences in tumor characteristics between Hispanic and non-Hispanic White (NHW) women using logistic regression modeling. 25,494 invasive breast cancer cases (23,657 NHWs and 1,837 Hispanics) reported to the cancer registry in 1995 to 2003 were included in the analysis.


RESULTS
In age-adjusted models, compared with NHW women, Hispanics were more likely to have high-grade cancers, larger tumors, a greater number of positive lymph nodes, and advanced stage at diagnosis. Hispanic women were less likely to have tumors that are both estrogen and progesterone receptor positive (ER+/PR+), particularly those under age 60.


CONCLUSIONS
The profile of tumor presentation in Hispanic women in Arizona is consistent with a more aggressive disease pattern and less favorable prognosis than that of NHWs.
Arizona Cancer Center, University of Arizona, Tucson, USA. emartinez@azcc.arizona.edu
María Elena
ME
Martínez
Carrie M
CM
Nielson
Ray
R
Nagle
Ana Maria
AM
Lopez
Christina
C
Kim
Patricia
P
Thompson
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001130:Arizona / Q000453:epidemiology; D001943:Breast Neoplasms / Q000208:ethnology* / Q000473:pathology; D018450:Disease Progression; D005260:Female; D006630:Hispanic or Latino / Q000706:statistics & numerical data*; D006801:Humans; D016015:Logistic Models; D008875:Middle Aged; D009367:Neoplasm Staging; D016017:Odds Ratio; D011960:Receptors, Estrogen / Q000032:analysis; D011980:Receptors, Progesterone / Q000032:analysis; D018426:SEER Program; D044465:White People / Q000706:statistics & numerical data*
D011960:Receptors, Estrogen; D011980:Receptors, Progesterone