Endonasal transsphenoidal pituitary surgery: is tumor volume a key factor in determining outcome?
OBJECTIVE
This study was conducted to evaluate the role of tumor volume in excision of pituitary adenomas.


METHODS
A total of 20 patients with pituitary adenoma underwent surgical excision of the tumor by endonasal transsphenoidal approach.


RESULTS
A preoperative tumor volume of more than 5 mL is associated with a 90.90% probability of residual tumor (P < .05, statistically significant).


CONCLUSIONS
Tumor volume as a predicting factor for the surgical outcome is an evolving concept. Other factors determining the efficacy of tumor removal are parasellar and suprasellar extension.
Jain
Amit Kumar
AK
Department of Otolaryngology & Head & Neck surgery, Post-Graduate Institute of Medical Education and Research, Chandigarh, India.
Gupta
Ashok Kumar
AK
Pathak
Ashis
A
Bhansali
Anil
A
Bapuraj
J Rajiv
JR
D000236:Adenoma / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D000293:Adolescent; D000328:Adult; D004724:Endoscopy / Q000379:methods*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D009666:Nose; D009929:Organ Size; D010911:Pituitary Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D011446:Prospective Studies; D013100:Sphenoid Bone / Q000601:surgery*; D014057:Tomography, X-Ray Computed / Q000379:methods*; D016896:Treatment Outcome