[Craniopharyngiomas: role of radiotherapy].
Craniopharyngiomas are benign tumors of the parasellar region, characterised by high relapsing rate. Aggressive attempt at total removal does result in prolonged progression-free survival in most patients. But for tumors that clearly involve the hypothalamus, complications associated with radical surgery have prompted to adopt a combined strategy of conservative surgery and radiation therapy to residual tumor with an as high rate of cure. This strategy seems to offer the best long-term control rates with acceptable morbidity. But optimal management of craniopharyngiomas remains controversial. Although it is generally recommended that radiotherapy is given following sub-total excision of a craniopharyngioma, it remains unclear as to whether all patients with residual tumour should receive immediate or differed at relapse radiotherapy.
Chargari
Cyrus
C
Oncologie-radiothérapie, HIA Val de Grâce, 74 boulevard de Port-Royal, 75230 Paris Cedex 05. chargari-vdg@hotmail.fr
Bauduceau
Olivier
O
Bauduceau
Bernard
B
Camparo
Philippe
P
Ceccaldi
Bernard
B
Fayolle
Maryse
M
Le Moulec
Sylvestre
S
Védrine
Lionel
L
D000367:Age Factors; D003397:Craniopharyngioma / Q000150:complications / Q000532:radiotherapy* / Q000601:surgery; D006801:Humans; D018365:Neoplasm, Residual / Q000532:radiotherapy; D010911:Pituitary Neoplasms / Q000150:complications / Q000532:radiotherapy* / Q000601:surgery; D011879:Radiotherapy Dosage; D047368:Tumor Burden