[Carcinoma of penis: report of 59 cases and review of literature].
OBJECTIVE
To analyze the characteristics and prognostic factor of penile cancer, we retrospectively reviewed the clinicopathological data of patients with a diagnosis of penile cancer treated.


METHODS
The records of 59 patients (median age 66, ranged from 47 to 91) with squamous cell carcinoma of the penis reffered between April 1988 and January 2006 were reviewed. The importance of tumor size and stage, differentiation, type of infiltration, vascular invasion, patient age, lymph node metastasis, distant metastasis and type of therapy were assessed using univariate and multivariate analyses.


RESULTS
After a mean follow up of 37.7 months, 13 cases (22.0%) died of cancer and 5-year survival was 67.4%. Multivariate analysis demonstrated that, type of operation (p = 0.0471, Hazard ratio 3.364), vascular invasion (p = 0.0014, Hazard ratio 5.921) were associated with survival.


CONCLUSIONS
Vascular invasion and type of operation were related to survival. Our findings indicate that correct pathological diagnosis and appropriate treatment may lead to prolonged survival.
Yumura
Yasushi
Y
Department of Urology, Yokohama Municipal Citizen's Hospital.
Moriyama
Masatoshi
M
Sasaki
Takeshi
T
Takase
Kazunori
K
Ooko
Yoshiharu
Y
Noguchi
Sumio
S
Miura
Takeshi
T
Kubota
Yoshinobu
Y
D000368:Aged; D000369:Aged, 80 and over; D000704:Analysis of Variance; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis / Q000473:pathology* / Q000556:secondary / Q000628:therapy*; D003131:Combined Modality Therapy; D005500:Follow-Up Studies; D006801:Humans; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D009367:Neoplasm Staging; D010412:Penile Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy*; D011379:Prognosis; D012189:Retrospective Studies