Lipid peroxidation: control of cell proliferation, cell differentiation and cell death.
In recent years, it has become evident that lipid peroxidation is not only a mechanism for deterioration of alimentary oils and fats, but can occur even in living cells, both in pathological and physiological conditions. Through its aldehydic products, it can regulate several cellular processes, as proliferation, differentiation and apoptosis of normal and neoplastic cells. In this review we describe some recent findings obtained in these fields.
Dipartimento di Medicina e Oncologia Sperimentale, Corso Raffaello 30, Torino, Italy.
Giuseppina
G
Barrera
Stefania
S
Pizzimenti
Mario Umberto
MU
Dianzani
D000818:Animals; D017209:Apoptosis / Q000502:physiology*; D002454:Cell Differentiation / Q000502:physiology*; D049109:Cell Proliferation; D006801:Humans; D015227:Lipid Peroxidation / Q000502:physiology*