Squamous cell carcinoma arising from an epidermal cyst.
There are few case reports in the English literature concerning malignant transformation of an epidermal cyst into squamous cell carcinoma. We report a case of squamous cell carcinoma arising from a 40-year epidermal cyst in the proximal left thigh of a 74-year-old man. The epidermal cyst had increased in size in the previous 3 years. The patient presented with a discharge from the lesion. Ultrasonography and magnetic resonance imaging of the lesion suggested malignancy. An intra-operative frozen section of an incisional biopsy of the lesion found it to be an epidermal cyst with suspected malignant change, so a marginal excision of the lesion was performed. Squamous cell carcinoma arising from the epidermal cyst was confirmed histologically. A wide excision was done in order to obtain an adequate resection margin. A computed tomographic scan of the thorax and abdomen found no evidence of metastases. No evidence of recurrence was noted in the latest follow-up, 2 years postoperatively.
Department of Orthopaedics and Traumatology, Caritas Medical Centre, Shamshuipo, Hong Kong. brianmychiu@yahoo.com
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Chiu
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Ho
D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000473:pathology*; D002471:Cell Transformation, Neoplastic; D004814:Epidermal Cyst / Q000473:pathology*; D006801:Humans; D008297:Male; D012878:Skin Neoplasms / Q000473:pathology*