High-resolution intermolecular zero-quantum coherence spectroscopy under inhomogeneous fields with effective solvent suppression.
Intermolecular zero-quantum coherences (iZQCs) are not susceptible to magnetic field inhomogeneities significantly larger than the dipolar correlation distance and can be used to obtain 1D high-resolution spectra in an inhomogeneous field. However, with the iZQC methods proposed previously, residual conventional single-quantum coherences (SQCs) originating mainly from solvent resonance result in strong t(1) ridge noises. A modified HOMOGENIZED with an intermolecular double-quantum filter (iDQF), named iDQF-HOMOGENIZED, is presented in this work to suppress the residual conventional SQC signals as well as solvent iZQC signals. The solvent-suppression efficiency of the iDQF-HOMOGENIZED is analyzed and a thorough comparison of the new sequence with several relevant pulse sequences is made. Dramatic resolution enhancement and solvent suppression in the measurements of a piece of grape sarcocarp suggest potential applications of the method in in vivo spectroscopy.
Department of Physics, State Key Laboratory of Physical Chemistry of Solid Surface, Xiamen University, Xiamen, 361005, PR China.
Xi
X
Chen
Meijin
M
Lin
Zhong
Z
Chen
Shuhui
S
Cai
Jianhui
J
Zhong
D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D011789:Quantum Theory; D012997:Solvents / Q000737:chemistry
D012997:Solvents