A computational framework for approximating boundary surfaces in 3-D biomedical images.
We propose a new method for detecting and approximating the boundary surfaces in three-dimensional (3-D) biomedical images. Using this method, each boundary surface in the original 3-D image is normalized as a zero-value isosurface of a new 3-D image transformed from the original 3-D image. A novel computational framework is proposed to perform such an image transformation. According to this framework, we first detect boundary surfaces from the original 3-D image and compute discrete samplings of the boundary surfaces. Based on these discrete samplings, a new 3-D image is constructed for each boundary surface such that the boundary surface can be well approximated by a zero-value isosurface in the new 3-D image. In this way, the complex problem of reconstructing boundary surfaces in the original 3-D image is converted into a task to extract a zero-value isosurface from the new 3-D image. The proposed technique is not only capable of adequately reconstructing complex boundary surfaces in 3-D biomedical images, but it also overcomes vital limitations encountered by the isosurface-extracting method when the method is used to reconstruct boundary surfaces from 3-D images. The performances and advantages of the proposed computational framework are illustrated by many examples from different 3-D biomedical images.
Wang
Lisheng
L
Department of Automation, Institute of Image Processing and Pattern Recognition, Shanghai Jiao Tong University, Shanghai 200030, China. lswang@sjtu.edu.cn
Bai
Jing
J
He
Ping
P
Heng
Pheng-Ann
PA
Yang
Xin
X
D000465:Algorithms; D001185:Artificial Intelligence; D003952:Diagnostic Imaging / Q000379:methods*; D007089:Image Enhancement / Q000379:methods*; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D021621:Imaging, Three-Dimensional / Q000379:methods*; D010363:Pattern Recognition, Automated / Q000379:methods*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity