[Multiple eruptive dermatofibromas in 2 patients infected with the human immunodeficiency virus].
Multiple eruptive dermatofibromas are an uncommon clinical entity in which several lesions appear in a short period of time. Baraf and Shapiro defined them in 1970 as the appearance of at least 15 dermatofibromas in a few months. Given that incipient cases might be omitted, appearance of 5 to 8 dermatofibromas in 4 months has been proposed as sufficient to establish diagnosis. Although this entity has been reported in healthy subjects, it usually appears with underlying autoimmune diseases (lupus erythematosus), human immunodeficiency virus (HIV) infection, or treatment with certain drugs. We report 2 cases of multiple eruptive dermatofibromas associated with HIV infection. One of these patients was unaware of being infected with HIV, and so we believe that the appearance of these skin lesions could help early diagnosis of autoimmune diseases or patients with immunodepression.
Servicio de Dermatología, Hospital Universitario Ramón y Cajal, Madrid, España. cgmillan@gmail.com
C
C
García-Millán
I
I
Aldanondo
M
M
Fernández-Lorente
R
R
Carrillo
P
P
Jaén
D000328:Adult; D005260:Female; D015658:HIV Infections / Q000150:complications*; D018219:Histiocytoma, Benign Fibrous / Q000209:etiology* / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D012878:Skin Neoplasms / Q000209:etiology* / Q000473:pathology