Plasma D-dimer levels in patients with typhoid fever.
The plasma levels of D-dimer can be used as a marker of fibrin formation and degradation. Plasma D-dimer levels in the febrile phase of 6 patients with typhoid fever and in the afebrile convalescent phase of 4 of them were measured. D-dimer levels were high in the febrile phase of all 6 patients and within normal range in the afebrile convalescent phase of all 4 patients. Our results indicate that thrombus formation and fibrinolysis may occur in the febrile phase of patients with typhoid fever.
Ohnishi
K
K
Department of Infectious Diseases, Tokyo Metropolitan Bokutoh General Hospital, Sumida City, Tokyo, Japan. infection@bokutoh-hp.metro.tokyo.jp
Nakamura-Uchiyama
F
F
Komiya
N
N
D000293:Adolescent; D000328:Adult; D005260:Female; D005334:Fever / Q000097:blood; D005337:Fibrin / Q000378:metabolism; D005338:Fibrin Fibrinogen Degradation Products / Q000378:metabolism*; D006801:Humans; D008297:Male; D013927:Thrombosis / Q000097:blood; D014435:Typhoid Fever / Q000097:blood*
D005338:Fibrin Fibrinogen Degradation Products; C036309:fibrin fragment D; D005337:Fibrin