Preparation of C60-based active esters and coupling of C60 moiety to amines or alcohols.
We report the syntheses of C(60)-based active esters and the coupling of their C(60) moiety to various amines or alcohols. Methano[60]fullerene carboxylic acid was activated by esterification with N-hydroxysuccinimide (NHS) or pentafluorophenol (PFP) and the active esters were isolated. Reactions of the active esters with amines or alcohols proceeded easily to give a variety of compounds having the C(60) moiety.
Tsumoto
Hiroki
H
Graduate School of Pharmaceutical Sciences, Nagoya City University, 3-1 Tanabedori, Nagoya, Aichi 467-8603, Japan.
Takahashi
Katsumasa
K
Suzuki
Takayoshi
T
Nakagawa
Hidehiko
H
Kohda
Kohfuku
K
Miyata
Naoki
N
D000438:Alcohols / Q000737:chemistry*; D000588:Amines / Q000737:chemistry*; D002851:Chromatography, High Pressure Liquid; D037741:Fullerenes / Q000737:chemistry*; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
D000438:Alcohols; D000588:Amines; D037741:Fullerenes; C069837:fullerene C60