Disseminated intravascular coagulation and a negative D-dimer test.
The diagnosis of disseminated intravascular coagulation (DIC) requires the presence of a fibrin-related marker. D-dimer is frequently used in clinical practice as a fibrin-related marker. We present a case of paraneoplastic DIC with a false-negative D-dimer test. Repeating the test using a different D-dimer assay as well as the measurement of other fibrinolysis markers confirmed the diagnosis of DIC.
Constantinescu
A A
AA
Department of Internal Medicine, Albert Schweitzer Hospital, Location Dordwijk, PO Box 444, 3300 AK Dordrecht, the Netherlands. a.constantinescu@asz.nl
Berendes
P B
PB
Levin
M-D
MD
D000368:Aged; D001681:Biological Assay; D015415:Biomarkers; D004211:Disseminated Intravascular Coagulation / Q000175:diagnosis* / Q000503:physiopathology; D005337:Fibrin; D005338:Fibrin Fibrinogen Degradation Products; D006801:Humans; D008297:Male
D015415:Biomarkers; D005338:Fibrin Fibrinogen Degradation Products; C036309:fibrin fragment D; D005337:Fibrin