Matrix-assisted laser desorption/ionization mechanism study with dihydroxybenzoic acid isomers as matrices.
Desorption and ionization efficiencies of matrix-assisted laser desorption/ionization (MALDI) for various biomolecules with different dihydroxybenzoic acid isomers were studied. No clear relationships were observed between MALDI biomolecule signals vs. gas-phase basicity, proton affinity and ionization potential. This indicates the the gas-phase protonation mechanism is not adequate to explain the observed results.
Genomics Research Center, Academia Sinica, Taipei, Taiwan.
Lori
L
Jessome
Nien-Yeen
NY
Hsu
Yi-Sheng
YS
Wang
Chung-Hsuan
CH
Chen
D062385:Hydroxybenzoates / Q000737:chemistry*; D007536:Isomerism; D009841:Oligonucleotides / Q000737:chemistry; D010455:Peptides / Q000737:chemistry; D011134:Polysaccharides / Q000737:chemistry; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / Q000379:methods*
D062385:Hydroxybenzoates; D009841:Oligonucleotides; D010455:Peptides; D011134:Polysaccharides