Plasma D-dimer levels in patients with typhoid fever.
The plasma levels of D-dimer can be used as a marker of fibrin formation and degradation. Plasma D-dimer levels in the febrile phase of 6 patients with typhoid fever and in the afebrile convalescent phase of 4 of them were measured. D-dimer levels were high in the febrile phase of all 6 patients and within normal range in the afebrile convalescent phase of all 4 patients. Our results indicate that thrombus formation and fibrinolysis may occur in the febrile phase of patients with typhoid fever.
Department of Infectious Diseases, Tokyo Metropolitan Bokutoh General Hospital, Sumida City, Tokyo, Japan. infection@bokutoh-hp.metro.tokyo.jp
K
K
Ohnishi
F
F
Nakamura-Uchiyama
N
N
Komiya
D000293:Adolescent; D000328:Adult; D005260:Female; D005334:Fever / Q000097:blood; D005337:Fibrin / Q000378:metabolism; D005338:Fibrin Fibrinogen Degradation Products / Q000378:metabolism*; D006801:Humans; D008297:Male; D013927:Thrombosis / Q000097:blood; D014435:Typhoid Fever / Q000097:blood*
D005338:Fibrin Fibrinogen Degradation Products; C036309:fibrin fragment D; D005337:Fibrin