Glycosylation reaction via a mild and efficient one-pot reaction using doped natural phosphate with iodine as catalyst.
Several alpha/beta-D-ribonucleosides were synthesized in good yields under mild conditions by N-glycosylations of acetyl 2,3,5-tri-O-benzoyl-beta-D-ribofuranose with silylated nucleobases in acetonitrile using NP doped with iodine as catalyst.
Lazrek
H B
HB
Faculté des Sciences Semlalia, Laboratoire de Chimie Bio-Organique, Marrakech, Maroc.
Ouzebla
D
D
Baddi
L
L
Vasseur
J J
JJ
D000970:Antineoplastic Agents / Q000138:chemical synthesis / Q000737:chemistry; D000998:Antiviral Agents / Q000138:chemical synthesis / Q000737:chemistry; D002384:Catalysis; D006031:Glycosylation; D007455:Iodine; D008722:Methods; D017646:Organosilicon Compounds; D010710:Phosphates; D012263:Ribonucleosides / Q000138:chemical synthesis* / Q000737:chemistry
D000970:Antineoplastic Agents; D000998:Antiviral Agents; D017646:Organosilicon Compounds; D010710:Phosphates; D012263:Ribonucleosides; D007455:Iodine; C024548:hexamethylsilazane