Outcome of early detection and radiotherapy for occult spinal cord compression.
Retrospective analysis in 150 patients with metastatic prostate cancer was conducted to determine whether early detection with MRI spine and treatment of clinically occult spinal cord compromise (SCC) facilitate preservation of neurologic function. Our results suggest that prophylactic radiotherapy for patients with back pain or radiological SCC without neurologic deficit may facilitate preservation of neurologic function. Thus MRI surveillance for SCC may be important for prostate cancer patients with bone metastases.
Venkitaraman
Ramachandran
R
Academic Urology Unit, Royal Marsden Hospital, Downs Road, Sutton, Surrey, UK.
Barbachano
Yolanda
Y
Dearnaley
David P
DP
Parker
Christopher C
CC
Khoo
Vincent
V
Huddart
Robert A
RA
Eeles
Rosalind
R
Horwich
Alan
A
Sohaib
S Aslam
SA
D000368:Aged; D000369:Aged, 80 and over; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009362:Neoplasm Metastasis; D011471:Prostatic Neoplasms / Q000150:complications; D012189:Retrospective Studies; D013117:Spinal Cord Compression / Q000175:diagnosis* / Q000532:radiotherapy*; D016896:Treatment Outcome