Simple palladium(II) precatalyst for Suzuki-Miyaura couplings: efficient reactions of benzylic, aryl, heteroaryl, and vinyl coupling partners.
trans-PdBr(N-Succ)(PPh3)2 (1) is a universally effective precatalyst for Suzuki-Miyaura cross-couplings of benzylic halides with aryl- or heteroarylboronic acids. Substituted aryl halides and halogenated cyclic enones can be cross-coupled with aryl- or vinylboronic acids in excellent yields. Catalyst recycling is also demonstrated.
Department of Chemistry, University of York, Heslington, York, YO10 5DD, UK.
Michael J
MJ
Burns
Ian J S
IJ
Fairlamb
Anant R
AR
Kapdi
Petr
P
Sehnal
Richard J K
RJ
Taylor
D001897:Boronic Acids / Q000737:chemistry; D002384:Catalysis; D010165:Palladium / Q000737:chemistry*
D001897:Boronic Acids; D010165:Palladium