Molecular targets of FoxP3+ regulatory T cells.
The important roles of FoxP3+ T cells in many immunological or cancerous diseases are now well established. The research field is now moving in the direction to fine-control the generation, migration, expansion, and function of FoxP3+ cells in an effort to prevent and cure specific types of diseases. Potential molecular targets to regulate FoxP3+ T cells are reviewed in this article.
Department of Comparative Pathobiology, 725 Harrison Street, Purdue University, West Lafayette, IN 47907, USA. chkim@purdue.edu
Chang H
CH
Kim
D000818:Animals; D016503:Drug Delivery Systems; D051858:Forkhead Transcription Factors / Q000096:biosynthesis; D006801:Humans; D007154:Immune System Diseases / Q000188:drug therapy; D050378:T-Lymphocytes, Regulatory / Q000187:drug effects / Q000276:immunology / Q000502:physiology*
C418974:FOXP3 protein, human; D051858:Forkhead Transcription Factors