[Drug side effects as the cause of gastrointestinal problems in elderly people].
Adverse drug reactions on the digestive tract are very common. Some special aspects must be heeded, especially in geriatric patients who often take several medications concomitantly. These include a potentially altered drug metabolism, possible lack of compliance, potential drug interactions as a result of polypharmaceutical therapy, the influence of comorbidities as well as the possibility of increased sensitivity and hence, toxic effect on the target organs.
Scheurlen
Michael
M
Medizinische Klinik und Poliklinik II, Universitätsklinikum Würzburg. Scheurlen_M@klinik.uni-wuerzburg.de
D000368:Aged; D056486:Chemical and Drug Induced Liver Injury / Q000175:diagnosis; D003248:Constipation / Q000139:chemically induced; D003967:Diarrhea / Q000139:chemically induced; D004347:Drug Interactions; D004359:Drug Therapy, Combination; D064420:Drug-Related Side Effects and Adverse Reactions; D005767:Gastrointestinal Diseases / Q000139:chemically induced* / Q000175:diagnosis; D006801:Humans; D008111:Liver Function Tests; D010599:Pharmacokinetics; D012307:Risk Factors