A transcriptome landscape of mouse embryogenesis.
Coordinated regulation of genetic activity underpins formation of the body plan and morphogenesis of embryonic structures. In this issue of Developmental Cell, Mitiku and Baker describe a chronological series of transcriptomes of postimplantation mouse embryos at gastrulation and early organogenesis, providing a valuable resource for studying the dynamics of both genome-wide and gene-specific transcriptional activities that accompany mouse embryogenesis.
Embryology Unit, Children's Medical Research Institute, University of Sydney, Locked Bag 23, Wentworthville NSW 2145, Australia.
Nicolas
N
Fossat
Sabine
S
Pfister
Patrick P L
PP
Tam
D000818:Animals; D047108:Embryonic Development / Q000235:genetics*; D005260:Female; D015870:Gene Expression; D020869:Gene Expression Profiling; D023281:Genomics; D051379:Mice / Q000196:embryology; D014158:Transcription, Genetic