Value of conventional chest radiography for the detection of coronary calcifications: comparison with MSCT.
OBJECTIVE
To evaluate if computed tomography (CT) coronary calcium scoring is needed after detection of coronary calcifications on conventional chest radiographs.


METHODS
One hundred and five patients (67 men; 57.2+/-12.8 years) with suspected coronary artery disease underwent conventional chest radiography and non-enhanced, retrospectively ECG-gated multislice spiral CT (MSCT) of the heart (4 mm x 2.5 mm, 120 kV, 133 mAs(eff.)). Chest radiographs were assessed independently by two radiologists. Detection of coronary calcifications was compared between both methods. Sensitivity, specificity, negative and positive predictive values, median, 25% and 75% percentiles for the detection of coronary calcifications were calculated. Receiver operating characteristics (ROC) analyses were computed.


RESULTS
In 90 patients, MSCT revealed coronary calcifications. The mean coronary calcium score was 526.2 (0-4784.5). On chest radiographs, coronary calcifications were correctly detected in 46 (61) patients by observer 1 (observer 2). The corresponding sensitivity was 51.1% in observer 1 and 67.8% in observer 2. Median of detected coronary calcifications was 361.9 (426.4) for observer 1 (observer 2). Corresponding 25% und 75% percentiles were 109.6 (109.6) and 798.5 (898.5). The area under the ROC curve was 0.636 for observer 1 and 0.715 for observer 2. There was no correlation between image quality and the detection of coronary calcifications on plain film radiographs.


CONCLUSIONS
As coronary calcifications of various extents are inconsistently detected on plain chest radiographs, CT calcium scoring may not be omitted even if coronary artery calcifications were detected on conventional chest radiographs.
Department of Diagnostic Radiology, University Hospital, RWTH Aachen University, Pauwelsstrasse 30, D-52074 Aachen, Germany. mahnken@rad.rwth-aachen.de
Andreas H
AH
Mahnken
Berthold B
BB
Wein
Anil M
AM
Sinha
Rolf W
RW
Günther
Joachim E
JE
Wildberger
D002114:Calcinosis / Q000000981:diagnostic imaging*; D017023:Coronary Angiography / Q000379:methods*; D003324:Coronary Artery Disease / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D013902:Radiography, Thoracic / Q000379:methods*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed / Q000379:methods*