Imaging of a large collection of human embryo using a super-parallel MR microscope.
Using 4 and 8-channel super-parallel magnetic resonance (MR) microscopes with a horizontal bore 2.34T superconducting magnet developed for 3-dimensional MR microscopy of the large Kyoto Collection of Human Embryos, we acquired T(1)-weighted 3D images of 1204 embryos at a spatial resolution of (40 microm)(3) to (150 microm)(3) in about 2 years. Similarity of image contrast between the T(1)-weighted images and stained anatomical sections indicated that T(1)-weighted 3D images could be used for an anatomical 3D image database for human embryology.
Institute of Applied Physics, University of Tsukuba, Ibaraki, Japan.
Yoshimasa
Y
Matsuda
Shinya
S
Ono
Yosuke
Y
Otake
Shinya
S
Handa
Katsumi
K
Kose
Tomoyuki
T
Haishi
Shigeto
S
Yamada
Chikako
C
Uwabe
Kohei
K
Shiota
D019992:Databases as Topic; D004622:Embryo, Mammalian / Q000033:anatomy & histology*; D016591:Histocytological Preparation Techniques; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D007091:Image Processing, Computer-Assisted / Q000379:methods; D021621:Imaging, Three-Dimensional / Q000379:methods; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008853:Microscopy / Q000379:methods*