Assessment of left ventricular dyssynchrony in patients with heart failure and normal QRS duration.
Cardiac resynchronization therapy (CRT) is an important component of heart failure therapy in patients with a left ventricular ejection fraction <35%, class III or ambulatory class IV symptoms, and a QRS duration >120 ms. The QRS duration criterion for patient selection is imperfect. About 30% of patients with an increased QRS duration are nonresponders to CRT and many with a normal QRS duration with mechanical dyssynchrony respond to CRT. The authors review the currently available echocardiographic tools for the assessment of ventricular dyssynchrony in patients with heart failure.
Division of Cardiology, University of Southern California-Keck School of Medicine, Los Angeles, CA, USA.
Vidya
V
Narayan
Padmini
P
Varadarajan
Ramdas G
RG
Pai
D004562:Electrocardiography / Q000379:methods; D006333:Heart Failure / Q000150:complications*; D006801:Humans; D018487:Ventricular Dysfunction, Left / Q000150:complications / Q000175:diagnosis* / Q000503:physiopathology / Q000628:therapy*