Endometrial cancer associated with defective DNA mismatch repair.
Defective DNA mismatch repair is one of the most common and best-characterized genetic defects detected in endometrial cancer. Defective DNA mismatch repair in endometrial cancer can be either inherited or acquired (sporadic). This article describes the clinical and pathologic significance of acquired and inherited defective DNA mismatch repair in endometrial cancer.
Department of Gynecologic Oncology, University of Texas MD Anderson Cancer Center, 1155 Herman Pressler, Houston, TX 77030, USA.
Pamela T
PT
Soliman
Karen
K
Lu
D053843:DNA Mismatch Repair; D004260:DNA Repair / Q000235:genetics; D004261:DNA Replication / Q000235:genetics; D016889:Endometrial Neoplasms / Q000235:genetics* / Q000473:pathology / Q000517:prevention & control; D005260:Female; D020022:Genetic Predisposition to Disease; D006801:Humans