Associations between substance use, erectile dysfunction medication and recent HIV infection among men who have sex with men.
We conducted a case-control study to compare illicit substance and erectile dysfunction medication (EDM) use between recently HIV-infected and uninfected men who have sex with men (MSM). Eighty-six recently (previous 12 months) HIV-infected MSM (cases) and 59 MSM who recently tested HIV-negative (controls) completed computer-assisted self-interviews. There were no statistical differences in demographics or number of sexual partners by HIV status. Cases were more likely than controls to report methamphetamine or nitrite use, but not EDM, gamma hydroxybutyrate, 3,4 methylenedioxymethamphetamine, cocaine, or marijuana use, in the previous 12 months and with their last three sexual partners in multivariate logistic regression models. Use of nitrites and amphetamine may increase HIV risk among MSM.
Division of International Health and Cross-Cultural Medicine, Department of Family and Preventive Medicine, School of Medicine, University of California, San Diego, 9500 Gilman Drive, Mail code 0622, La Jolla, CA 92093, USA. ldrumrig@ucsd.edu
Lydia N
LN
Drumright
Pamina M
PM
Gorbach
Susan J
SJ
Little
Steffanie A
SA
Strathdee
D000328:Adult; D002140:California / Q000453:epidemiology; D016022:Case-Control Studies; D007172:Erectile Dysfunction / Q000150:complications / Q000188:drug therapy*; D015658:HIV Infections / Q000097:blood / Q000150:complications / Q000453:epidemiology* / Q000635:transmission; D018451:Homosexuality, Male; D006801:Humans; D008297:Male; D010726:Phosphodiesterase Inhibitors / Q000627:therapeutic use*; D012725:Sexual Behavior; D015819:Substance Abuse, Intravenous / Q000150:complications / Q000453:epidemiology*
D010726:Phosphodiesterase Inhibitors