Sarcoidosis-like reaction related to Propionibacterium acnes and immune restoration syndrome in HIV infection .
Propionibacterium acnes is thought to be a potential triggering agent of sarcoidosis. We describe a woman who developed chronic meningitis with sarcoid-like multisystemic involvement under treatment for human immunodeficiency virus infection. P. acnes was isolated from cerebrospinal fluid. We assume that P. acnes might have triggered this sarcoid-like reaction with meningitis, as a consequence of an immune reconstitution.
Department of Internal Medicine, Centre national de référence pour les vascularites et la sclérodermie, Hôpital Cochin, Université Paris-Descartes, Paris, France.
Khalil
K
El Karoui
Fanny
F
Lanternier
Anne
A
Brunet
Philippe
P
Blanche
Loïc
L
Guillevin
D000328:Adult; D023241:Antiretroviral Therapy, Highly Active / Q000009:adverse effects; D003937:Diagnosis, Differential; D005260:Female; D015658:HIV Infections / Q000188:drug therapy*; D015497:HIV-1; D006801:Humans; D054019:Immune Reconstitution Inflammatory Syndrome / Q000382:microbiology*; D016920:Meningitis, Bacterial / Q000382:microbiology*; D011425:Propionibacterium acnes / Q000302:isolation & purification*; D012507:Sarcoidosis / Q000382:microbiology*