Phase-sensitive inversion recovery single-shot balanced steady-state free precession for detection of myocardial infarction during a single breathhold.
OBJECTIVE
We sought to show that phase-sensitive detection and a single-shot technique allow imaging of the heart for detection of myocardial infarction during a single breathhold without adaptation of the inversion time.


METHODS
Thirty-five patients at 2 weeks to 3 months after Q-wave myocardial infarction were examined on a 1.5-T MR system 10 minutes after the administration of a double-dose extravascular contrast agent. In order to determine the optimal inversion recovery time (TI), a TI scout sequence was performed. An IR-turboFlash sequence with optimized TI was used as standard of reference. A phase-sensitive inversion recovery (PSIR) single-shot TrueFISP sequence, which allows imaging of nine slices during one breathhold (TR/TE/FA/BW: 2.2 ms/1.1 ms/60 degrees , 8 degrees /1220 Hz/Px) was used with a nominal TI of 200 ms. Spatial resolution was identical for both techniques: 1.3 mm x 1.8 mm x 8 mm. Infarct volumes, area of infarction on a selected slice, and scan time for imaging delayed contrast enhancement (DCE) were compared.


RESULTS
The mean values for the time of imaging DCE were 10 minutes 43 seconds for the IR turboFLASH and 17 seconds (P<.001) for the PSIR single-shot TrueFISP sequence. No significant difference was found for the mean values of the infarct volumes with 18.7 ml (IR turboFLASH) and 17.3 ml (PSIR single-shot TrueFISP). The values for the correlation coefficients of the infarct volumes and infarct areas of the two different techniques were r=0.95 (P<.004) and r=0.97 (P<.002). The regression equations were y=0.76+0.92*x and y=0.07+0.93*x, respectively.


CONCLUSIONS
PSIR single-shot TrueFISP allows for accurate identification of myocardial infarction during a single breathhold with reduction of scan time by a factor of 38.
Huber
Armin
A
Institut für Klinische Radiologie, Klinikum der LMU, Grosshadern, Marchioninistr. 15, 81377 München, Germany. Armin.Huber@ikra.med.uni-muenchen.de
Hayes
Carmel
C
Spannagl
Benedikt
B
Rieber
Johannes
J
Klauss
Volker
V
Schoenberg
Stefan Oswald
SO
Reiser
Maximilion
M
Wintersperger
Bernd Jürgen
BJ
D000328:Adult; D000368:Aged; D003287:Contrast Media; D005260:Female; D005500:Follow-Up Studies; D006346:Heart Septum / Q000473:pathology; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000175:diagnosis* / Q000473:pathology; D009206:Myocardium / Q000473:pathology; D011446:Prospective Studies; D013997:Time Factors
D003287:Contrast Media