[Assessment of immunity and allergy after vaccination with dry combined anthrax vaccine].
Study of humoral immune response and allergy in recipients of dry combined anthrax vaccine was performed. Immune response was assessed by antibody titers to protective antigen and by index of preventive properties of blood serum (PPS) of recipients. Relation of index of PPS and antibody titers in blood serum of the donors was established. Distribution of erythrocyte antigens in recipients of live dry and combined anthraxvaccines depending on blood group, Rh-factor, and age was studied. It has been shown that 80% of recipients of dry combined anthrax vaccine formed potent immunity with its high level lasted for 8 months. Study of allergenic properties of the combined anthrax vaccine using registration of neutrophils chemiluminescence in vivo showed low level of sensitization of vacinees.
A N
AN
Shevtsov
I V
IV
Darmov
G A
GA
Saîtseva
D V
DV
Borovskoî
V A
VA
Menovshchikov
V K
VK
Kunof
T A
TA
Gracheva
D000328:Adult; D000818:Animals; D000881:Anthrax / Q000097:blood / Q000276:immunology* / Q000517:prevention & control; D022122:Anthrax Vaccines / Q000008:administration & dosage / Q000009:adverse effects* / Q000276:immunology*; D000907:Antibodies, Bacterial / Q000097:blood; D000942:Antigens, Bacterial / Q000009:adverse effects / Q000276:immunology*; D001408:Bacillus anthracis / Q000276:immunology*; D001789:Blood Group Antigens / Q000097:blood; D005260:Female; D006801:Humans; D006967:Hypersensitivity / Q000209:etiology*; D007106:Immune Sera / Q000276:immunology*; D007116:Immunization, Passive; D007279:Injections, Subcutaneous; D008297:Male; D051379:Mice; D012204:Rh-Hr Blood-Group System / Q000097:blood; D013997:Time Factors; D017778:Vaccines, Combined / Q000008:administration & dosage / Q000009:adverse effects / Q000276:immunology
D022122:Anthrax Vaccines; D000907:Antibodies, Bacterial; D000942:Antigens, Bacterial; D001789:Blood Group Antigens; D007106:Immune Sera; D012204:Rh-Hr Blood-Group System; D017778:Vaccines, Combined