A patient-centered clinical evaluation of acellular dermal matrix graft in the treatment of gingival recession defects.
BACKGROUND
The present randomized controlled trial was conducted to evaluate acellular dermal matrix (ADM) graft in terms of patient satisfaction and its effectiveness and efficiency in the treatment of gingival recession.


METHODS
Fourteen patients (seven males and seven females) with Miller Class I and II recessions > or =3 mm participated in this 6-month clinical study. They were assigned randomly to the ADM group (ADM graft and coronally positioned flap [CPF]) or the CPF group (CPF alone). Results were evaluated based on parameters measuring patient satisfaction and clinical outcomes associated with the two treatment procedures. Significance was set at P <0.05.


RESULTS
The mean recession was 4.0 +/- 1.0 mm and 3.7 +/- 0.7 mm for the ADM and CPF groups, respectively. For the ADM group, the defect coverage was 3.85 +/- 0.89 mm or 97.14% compared to the CPF group, in which the defect coverage was 2.85 +/- 0.89 mm or 77.42%. The difference between the two groups was statistically significant (P <0.05). There were no statistically significant differences between the two groups in the remaining clinical parameters and overall patient satisfaction except in criteria related to patient comfort and cost effectiveness, in which CPF alone produced significantly better results (P <0.03).


CONCLUSIONS
ADM graft is significantly superior with regard to effectiveness and efficiency in the treatment of gingival recession than CPF alone. CPF emerges as a better option than ADM graft in terms of cost effectiveness and patient comfort.
Mahajan
Ajay
A
Department of Periodontics, King George's University of Dental Sciences, Lucknow, India. julius05@rediffmail.com
Dixit
Jaya
J
Verma
Umesh Pratap
UP
D000293:Adolescent; D000328:Adult; D000704:Analysis of Variance; D003094:Collagen / Q000627:therapeutic use*; D005260:Female; D005889:Gingival Recession / Q000601:surgery*; D005893:Gingivoplasty / Q000379:methods* / Q000523:psychology; D006801:Humans; D008297:Male; D017060:Patient Satisfaction; D018802:Patient-Centered Care; D016038:Skin Transplantation; D017768:Skin, Artificial; D013524:Surgical Flaps; D016896:Treatment Outcome
C440568:Alloderm; D003094:Collagen