Effect of gold nanoparticles on spermatozoa: the first world report.
OBJECTIVE
To evaluate the spermatotoxicity of gold nanoparticles.


METHODS
Experimental study.


METHODS
A university in Thailand.


METHODS
Single-donor fresh semen sample.


METHODS
A mixture of gold nanoparticle solution and semen was prepared and further analyzed.


METHODS
Spermatozoa appearance.


RESULTS
After mixing the semen with a gold nanoparticle solution, 25% of sperm were not motile. Penetration of gold nanoparticle into the sperm heads and tails was observed.


CONCLUSIONS
Spermatotoxicity of the gold nanoparticle can be detected.
Department of Clinical Laboratory Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand. wviroj@yahoo.com
Viroj
V
Wiwanitkit
Amornpun
A
Sereemaspun
Rojrit
R
Rojanathanes
D006046:Gold / Q000633:toxicity*; D006801:Humans; D008297:Male; D053758:Nanoparticles; D012016:Reference Values; D012661:Semen / Q000187:drug effects / Q000502:physiology; D013094:Spermatozoa / Q000187:drug effects / Q000502:physiology*
D006046:Gold