Microwave-assisted synthesis of dihydropyrimidin-2(1H)-ones using graphite supported lanthanum chloride as a mild and efficient catalyst.
Graphite supported lanthanum chloride efficiently catalyzes the three-component coupling of beta-ketoesters, aldehydes and urea/thiourea to afford corresponding dihydropyrimidinones in good yields under microwave irradiation.
Department of Chemistry, Shahid Bahonar University of Kerman, 76169 Kerman, Iran.
Hojatollah
H
Khabazzadeh
Kazem
K
Saidi
Hassan
H
Sheibani
D000447:Aldehydes / Q000737:chemistry; D002384:Catalysis; D004952:Esters / Q000737:chemistry; D006108:Graphite / Q000737:chemistry*; D007659:Ketones / Q000737:chemistry; D007811:Lanthanum / Q000737:chemistry*; D008872:Microwaves; D011744:Pyrimidinones / Q000138:chemical synthesis*; D013890:Thiourea / Q000737:chemistry; D014508:Urea / Q000737:chemistry
D000447:Aldehydes; D004952:Esters; D007659:Ketones; D011744:Pyrimidinones; C028521:lanthanum chloride; D007811:Lanthanum; D006108:Graphite; D014508:Urea; D013890:Thiourea