A noninvasive, presurgical expressive and receptive language investigation in a 9-year-old epileptic boy using near-infrared spectroscopy.
The intracarotid amobarbital test (IAT) is used for presurgical evaluation of language lateralization. However, this procedure has many limitations, especially in children. As an alternative to IAT, in the case described here, near-infrared spectroscopy (NIRS) was used to investigate expressive and receptive language lateralization as part of the presurgical evaluation of a 9-year-old Yiddish-speaking boy with a probable left temporal epileptic focus. This child could not tolerate IAT or functional MRI. He underwent two NIRS recording sessions while performing expressive and receptive language tasks. Results indicated predominantly left-sided expressive language in Broca's area with ipsilateral cortical recruitment of more posterior regions. Receptive language showed a bilateral cerebral pattern, perhaps as an expression of cerebral plasticity or compensation in this young patient. This case report illustrates that NIRS may contribute to presurgical investigation and could become a noninvasive alternative to IAT and functional MRI in determining speech lateralization in children.
Centre de Recherche du Centre Hospitalier Universitaire Sainte-Justine, Montréal, QC, Canada.
Anne
A
Gallagher
Danielle
D
Bastien
Isabelle
I
Pelletier
Phetsamone
P
Vannasing
Alan D
AD
Legatt
Solomon L
SL
Moshé
Rana
R
Jehle
Lionel
L
Carmant
Franco
F
Lepore
Renée
R
Béland
Maryse
M
Lassonde
D001931:Brain Mapping / Q000379:methods*; D002560:Cerebrovascular Circulation; D002648:Child; D004827:Epilepsy / Q000150:complications* / Q000601:surgery; D007839:Functional Laterality; D006801:Humans; D007806:Language Disorders / Q000150:complications / Q000175:diagnosis*; D008297:Male; D019265:Spectroscopy, Near-Infrared; D013702:Temporal Lobe / Q000098:blood supply* / Q000503:physiopathology; D014705:Verbal Behavior