Iridium catalysed synthesis of piperazines from diols.
A green and atom-economical method has been developed for the synthesis of piperazines by cyclocondensation of diols and amines in aqueous media in the presence of a catalytic amount of [Cp*IrCl2]2.
Center for Sustainable and Green Chemistry, Department of Chemistry, Building 201, Technical University of Denmark, DK-2800 Lyngby, Denmark.
Lars Ulrik
LU
Nordstrøm
Robert
R
Madsen
D000438:Alcohols / Q000737:chemistry; D000478:Alkylation; D000588:Amines / Q000737:chemistry; D002384:Catalysis; D007495:Iridium / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D010879:Piperazines / Q000138:chemical synthesis* / Q000737:chemistry; D012997:Solvents
D000438:Alcohols; D000588:Amines; D010879:Piperazines; D012997:Solvents; D007495:Iridium