Much HUBbub about stem-cell niches.
Stem cells, and the microenvironment or 'niche' that influences them, must often reside in a particular location within a tissue to perform their function. Integrin-mediated adhesion is now shown to regulate the location of the stem-cell niche in the Drosophila testis.
Van Doren
Mark
M
D000818:Animals; D002448:Cell Adhesion; D002454:Cell Differentiation; D019070:Cell Lineage; D004330:Drosophila / Q000166:cytology* / Q000196:embryology / Q000254:growth & development; D005109:Extracellular Matrix / Q000378:metabolism; D016023:Integrins / Q000378:metabolism; D008297:Male; D013234:Stem Cells / Q000166:cytology* / Q000502:physiology; D013737:Testis / Q000166:cytology / Q000196:embryology / Q000254:growth & development
D016023:Integrins