Subject-specific biomechanical simulation of brain indentation using a meshless method.
We develop a meshless method for simulating soft organ deformation. The method is motivated by simple, automatic model creation for real-time simulation. Our method is meshless in the sense that deformation is calculated at nodes that are not part of an element mesh. Node placement is almost arbitrary. Fully geometrically nonlinear total Lagrangian formulation is used. Geometric integration is performed over a regular background grid that does not conform to the simulation geometry. Explicit time integration is used via the central difference method. To validate the method we simulate indentation of a swine brain and compare the results to experimental data.
Horton
Ashley
A
Intelligent Systems for Medicine Laboratory, School of Mechanical Engineering, The University of Western Australia.
Wittek
Adam
A
Miller
Karol
K
D000818:Animals; D001696:Biomechanical Phenomena / Q000379:methods*; D001921:Brain / Q000502:physiology* / Q000601:surgery*; D003198:Computer Simulation; D004548:Elasticity; D020342:Finite Element Analysis; D006244:Hardness; D008959:Models, Neurological; D010812:Physical Stimulation / Q000379:methods*; D013314:Stress, Mechanical; D013552:Swine