Strong inhibition of cholera toxin binding by galactose dendrimers.
Galactose-containing dendrimers with long spacer arms inhibit cholera toxin binding as strongly as the natural ganglioside GM1 oligosaccharide does.
Branderhorst
Hilbert M
HM
Department of Medicinal Chemistry and Chemical Biology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, PO Box 80082, 3508 TB Utrecht, The Netherlands.
Liskamp
Rob M J
RM
Visser
Gerben M
GM
Pieters
Roland J
RJ
D002772:Cholera Toxin / Q000737:chemistry*; D018360:Crystallography, X-Ray; D050091:Dendrimers / Q000737:chemistry*; D005690:Galactose / Q000737:chemistry*; D008958:Models, Molecular; D015394:Molecular Structure; D012997:Solvents
D050091:Dendrimers; D012997:Solvents; D002772:Cholera Toxin; D005690:Galactose