Changes of multi-drug resistance pattern in Salmonella enterica subspecies enterica serovar typhimurium isolates from food-producing animals in Japan.
A total of 153 isolates of Salmonella Typhimurium derived from food-producing animals in Japan between 2002 and 2005 were investigated for antimicrobial resistance and phage types related to definitive phage type 104 (DT104). The predominant resistance type was resistance to ampicillin, dihydrostreptomycin, kanamycin, and oxytetracycline in bovine (45.2%, 48/104) and resistance to dihydrostreptomycin and oxytetracycline in porcine isolates (58.7%, 27/48). DT104-related phage type was found in 32 of 104 bovine isolates, two of 48 porcine isolates, and one of eight isolates from poultry, showing that the proportion of the phage type in S. Typhimurium isolates from cattle and pigs significantly (P<0.01) decreased from 71.9% and 31.4% in 1999-2001 to 30.8% and 4.1% in 2002-2005, respectively.
National Veterinary Assay Laboratory, Ministry of Agriculture, Forestry and Fisheries, Kokubunji, Tokyo 185-8511, Japan.
Kumiko
K
Kawagoe
Hiroko
H
Mine
Tetsuo
T
Asai
Akemi
A
Kojima
Kanako
K
Ishihara
Kazuki
K
Harada
Manao
M
Ozawa
Hidemasa
H
Izumiya
Jun
J
Terajima
Haruo
H
Watanabe
Eiichi
E
Honda
Toshio
T
Takahashi
Toshiya
T
Sameshima
D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D002417:Cattle; D002418:Cattle Diseases / Q000453:epidemiology / Q000382:microbiology; D024901:Drug Resistance, Multiple, Bacterial; D005516:Food Microbiology; D007564:Japan / Q000453:epidemiology; D011200:Poultry / Q000382:microbiology; D011201:Poultry Diseases / Q000453:epidemiology / Q000382:microbiology; D012481:Salmonella Infections, Animal / Q000382:microbiology*; D012486:Salmonella typhimurium / Q000187:drug effects / Q000235:genetics / Q000302:isolation & purification*; D013552:Swine / Q000382:microbiology; D013553:Swine Diseases / Q000453:epidemiology / Q000382:microbiology; D013997:Time Factors
D000900:Anti-Bacterial Agents