Neurogenesis and stroke.
Stroke stimulates neurogenesis in select regions of the adult brain, and the newborn neurons that result can migrate to areas of ischemic injury, where they may have the capacity to enhance brain recovery. These observations suggest that stroke-induced neurogenesis may contribute to endogenous brain repair after stroke, and that the mechanisms that underlie neurogenesis may represent potential therapeutic targets. Alternatively, transplantation of exogenously derived neural cells might also be an approach to the treatment of stroke.
Buck Institute for Age Research, 8001 Redwood Boulevard, Novato, CA 94945, USA. dgreenberg@buckinstitute.org
David A
DA
Greenberg
D000818:Animals; D001921:Brain / Q000254:growth & development* / Q000473:pathology*; D006801:Humans; D009474:Neurons / Q000187:drug effects / Q000502:physiology*; D018697:Nootropic Agents / Q000494:pharmacology / Q000627:therapeutic use; D020521:Stroke / Q000188:drug therapy / Q000473:pathology*
D018697:Nootropic Agents