Hepatoid adenocarcinoma of the gallbladder: a mimicker of hepatocellular carcinoma.
We present a case of a large gallbladder tumour in a patient with no known liver disease and elevated alpha-fetoprotein (AFP), in whom a differential diagnosis from hepatocellular carcinoma (HCC) in a non-cirrhotic liver was particularly difficult given the combination of the size of the tumour, solitary nature, elevated AFP and striking resemblance with HCC at histology. In presenting this patient, we would like to emphasise the role of MRI as a problem-solving tool for analysis of rare tumours of non-hepatocellular origin, including hepatoid adenocarcinoma of the gallbladder.
Department of Radiology, University Medical Center Rotterdam, The Netherlands. vandenbos.ic@gmail.com
I C
IC
van den Bos
S M
SM
Hussain
R S
RS
Dwarkasing
H
H
Stoop
P E
PE
Zondervan
G P
GP
Krestin
R A
RA
de Man
D000230:Adenocarcinoma / Q000175:diagnosis* / Q000473:pathology; D006528:Carcinoma, Hepatocellular / Q000175:diagnosis*; D003937:Diagnosis, Differential; D005260:Female; D005706:Gallbladder Neoplasms / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D008113:Liver Neoplasms / Q000175:diagnosis*; D008279:Magnetic Resonance Imaging; D008875:Middle Aged