Cancer-associated nummular loss of the retinal pigment epithelium.
OBJECTIVE
To report a case of cancer-associated nummular loss of the retinal pigment epithelium.


METHODS
A 47-year-old man with a history of hepatocellular carcinoma presented with three weeks of bilateral visual loss. His best-corrected visual acuity was 20/40 in each eye. He had multiple round confluent grayish-brown patches at the level of retinal pigment epithelium, and no pigmented choroidal lesions. Fluorescein angiography showed circular areas of transmission defect and indocyanine green angiography showed early hyperfluorescence, corresponding with the multiple round confluent patches.


CONCLUSIONS
We report a case of visual paraneoplastic syndrome which showed nummular loss of the pigment epithelial cells which distinguishes the clinical component of BDUMP syndrome.
Department of Ophthalmology, Gangnam Sacred Heart Hospital, College of Medicine, Hallym University, Seoul, Korea.
Jun Mok
JM
Lee
Hyun Kyung
HK
Seong
Woo Ho
WH
Nam
Ha Kyoung
HK
Kim
D006528:Carcinoma, Hepatocellular / Q000473:pathology*; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D005451:Fluorescein Angiography; D005654:Fundus Oculi; D006801:Humans; D008113:Liver Neoplasms / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D010257:Paraneoplastic Syndromes / Q000175:diagnosis*; D010857:Pigment Epithelium of Eye / Q000473:pathology*; D012164:Retinal Diseases / Q000175:diagnosis*; D041623:Tomography, Optical Coherence