Gene therapy in head and neck cancer: a review.
Gene therapy for cancer is a rapidly evolving field with head and neck squamous cell cancer being one of the more frequently targeted cancer types. The number of clinical trials in the UK is growing and there is already a commercially available agent in China. Various gene therapy strategies along with delivery mechanisms for targeting head and neck cancer are reviewed.
Molecular Oncology, Cancer Research UK, Barts and The London NHS Trust, London, UK. edwardchisholm@doctors.org.uk
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D002294:Carcinoma, Squamous Cell / Q000628:therapy*; D015316:Genetic Therapy / Q000379:methods*; D005822:Genetic Vectors / Q000627:therapeutic use*; D006258:Head and Neck Neoplasms / Q000628:therapy*; D006801:Humans