Wavefront- versus topography-guided customized ablations with the NIDEK EC-5000 CX II in surface ablation treatment: refractive and aberrometric outcomes.
OBJECTIVE
To compare the long-term refractive outcomes and changes in higher order wavefront aberrations in patients undergoing photorefractive keratectomy (PRK) with topography-guided (CATz) or wavefront-guided (OPDCAT) ablation algorithm using the NIDEK Advanced Vision Excimer Laser System (NAVEX).


METHODS
A retrospective 12-month follow-up study was conducted of 226 eyes undergoing PRK. The NIDEK EC-5000 CX II excimer laser and Final Fit 1.11 treatment planning software were used. Sixty-eight eyes underwent OPDCAT ablation and 158 eyes underwent CATz ablation. Mean preoperative manifest refractive spherical equivalent (MRSE) was -5.73 +/- 2.03 diopters (D) (range: -11.25 to -2.50 D) in the OPDCAT group and -3.77 +/- 3.78 D (range: -12.50 to -5.75 D) in the CATz group.


RESULTS
At 12 months postoperatively, mean MRSE was 0.05 D for the OPDCAT group and plano for the CATz group. Stability was similar in both groups as were visual outcomes. No eyes lost 2 or more lines of BSCVA at 6 months postoperatively or later. Mean ocular wavefront higher order aberrations at 3 months postoperatively were 0.44 +/- 0.17 microm for the OPDCAT group and 0.55 +/- 0.27 microm for the CATz group.


CONCLUSIONS
Refractive outcomes were equivalent between eyes that underwent PRK with wavefront-guided ablation and those that underwent topography-guided ablation.
Department of Ophthalmology, Istituto Clinico Humanitas, Rozzano, Milan, Italy. paolo.vinciguerra@humanitas.it
Paolo
P
Vinciguerra
Elena
E
Albè
Fabrizio I
FI
Camesasca
Silvia
S
Trazza
Daniel
D
Epstein
D000328:Adult; D000465:Algorithms; D019781:Corneal Topography / Q000592:standards; D003941:Diagnostic Techniques, Ophthalmological / Q000592:standards; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D054018:Lasers, Excimer; D008297:Male; D008875:Middle Aged; D018903:Photorefractive Keratectomy / Q000009:adverse effects; D011184:Postoperative Period; D011300:Preoperative Care; D012029:Refraction, Ocular; D012189:Retrospective Studies; D016896:Treatment Outcome; D014792:Visual Acuity