Chromosomal rearrangements in lipofibromatosis.
Lipofibromatosis is a relatively rare pediatric neoplasm, which usually manifests as an ill-defined soft tissue mass involving the upper and lower distal extremities, the trunk, and, less frequently, the head. To date, no cytogenetic abnormalities have been reported in this uncommon neoplasm. We present a case of lipofibromatosis featuring a three-way t(4;9;6) translocation in a 5-year-old boy.
Kenney
Barton
B
Department of Pathology, Yale University School of Medicine, 430 Congress Avenue, P.O. Box 208023, New Haven, CT 06520-8023, USA.
Richkind
Kathleen E
KE
Friedlaender
Gary
G
Zambrano
Eduardo
E
D002675:Child, Preschool; D002869:Chromosome Aberrations; D002894:Chromosomes, Human, Pair 4; D002896:Chromosomes, Human, Pair 6; D002899:Chromosomes, Human, Pair 9; D006801:Humans; D007621:Karyotyping; D008067:Lipoma / Q000235:genetics* / Q000473:pathology; D008279:Magnetic Resonance Imaging; D008297:Male; D014178:Translocation, Genetic