McCune-Albright syndrome associated with acromegaly and bipolar affective disorder.
McCune-Albright syndrome is a rare disorder caused by an activating mutation in the gene (GNAS1) encoding the subunit of the G protein. This syndrome is characterized by polyostotic fibrous dysplasia, café-au-lait pigmentation, and multiple endocrine hyperfunction. A 29-year-old male with polyostotic fibrous dysplasia, café-au-lait pigmentations, and pituitary adenoma is presented in this report. The patient had accompanying bipolar affective disorder, which might have been caused by the underlying genetic abnormality.
Ozcan-Kara
Pelin
P
Hacettepe University, Hacettepe Medical School, Department of Nuclear Medicine, 06100-Sihhiye, Ankara, Turkey.
Mahmoudian
Babek
B
Erbas
Belkis
B
Erbas
Tomris
T