Chlorodifluoromethyl phenyl sulfone: a novel non-ozone-depleting substance-based difluorocarbene reagent for O- and N-difluoromethylations.
Chlorodifluoromethyl phenyl sulfone, a previously unknown compound that can be readily prepared from non-ODS-based precursors, was found to act as a robust difluorocarbene reagent for O- and N-difluoromethylations.
Zheng
Ji
J
Key Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 354 Fenglin Road, Shanghai 200032, China.
Li
Ya
Y
Zhang
Laijun
L
Hu
Jinbo
J
Meuzelaar
Gerrit Joost
GJ
Federsel
Hans-Jürgen
HJ
D006845:Hydrocarbons, Fluorinated / Q000138:chemical synthesis* / Q000737:chemistry*; D006846:Hydrocarbons, Halogenated / Q000138:chemical synthesis / Q000737:chemistry*; D008745:Methylation; D015394:Molecular Structure; D013237:Stereoisomerism; D013450:Sulfones / Q000138:chemical synthesis / Q000737:chemistry*
D006845:Hydrocarbons, Fluorinated; D006846:Hydrocarbons, Halogenated; D013450:Sulfones; C526882:chlorodifluoromethyl phenyl sulfone; C121084:difluorocarbene