IgG4-positive pulmonary disease.
We report herein high-resolution computed tomography findings from a patient with IgG4-related pulmonary disease for the first time. The 61-year-old male patient complained of low-grade fever, dry mouth, and night sweats. He was diagnosed as having autoimmune pancreatitis, Sjögren syndrome, and elevated serum IgG4. High-resolution computed tomography of the lungs showed dense alveolar consolidation and air bronchograms in bilateral perihilar regions. IgG4-positive lymphoplasmacytes were detected in pulmonary lesions by immunostaining of biopsy samples. IgG4-related pulmonary disease can be associated with various radiologic findings.
Kobayashi
Hideo
H
Division of Respiratory Medicine, Department of Medicine, National Defense Medical College, Namiki, Tokorozawa, Japan. kobahide@ndmc.ac.jp
Shimokawaji
Tadasuke
T
Kanoh
Soichiro
S
Motoyoshi
Kazuo
K
Aida
Shinsuke
S
D001706:Biopsy; D003937:Diagnosis, Differential; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood*; D008171:Lung Diseases / Q000097:blood / Q000000981:diagnostic imaging* / Q000276:immunology; D008297:Male; D008875:Middle Aged; D010195:Pancreatitis / Q000097:blood / Q000175:diagnosis / Q000276:immunology; D012859:Sjogren's Syndrome / Q000097:blood / Q000175:diagnosis / Q000276:immunology; D014057:Tomography, X-Ray Computed
D007074:Immunoglobulin G