Ginger (Zingiber officinale Roscoe): a hot remedy for cardiovascular disease?
Ginger is now exciting considerable interest for its potential to treat many aspects of cardiovascular disease. This letter reviews the more recent trials, which suggest that ginger shows considerable anti-inflammatory, antioxidant, anti-platelet, hypotensive and hypolipidemic effect in in vitro and animal studies. Human trials have been few and generally used a low dose with inconclusive results, however dosages of 5 g or more demonstrated significant anti-platelet activity. More human trials are needed using an appropriate dosage of a standardised extract. Should these prove positive, ginger has the potential to offer not only a cheaper natural alternative to conventional agents but one with significantly lower side effects.
Rachel
R
Nicoll
Michael Y
MY
Henein
D000818:Animals; D000893:Anti-Inflammatory Agents / Q000494:pharmacology; D000959:Antihypertensive Agents / Q000494:pharmacology; D000975:Antioxidants / Q000494:pharmacology; D002318:Cardiovascular Diseases / Q000628:therapy*; D020939:Zingiber officinale / Q000737:chemistry; D006801:Humans; D000960:Hypolipidemic Agents / Q000494:pharmacology; D008517:Phytotherapy; D010975:Platelet Aggregation Inhibitors / Q000494:pharmacology
D000893:Anti-Inflammatory Agents; D000959:Antihypertensive Agents; D000975:Antioxidants; D000960:Hypolipidemic Agents; D010975:Platelet Aggregation Inhibitors