Peribulbar tramadol, clonidine, and ropivacaine in blind and seeing painful eyes.
OBJECTIVE
To report on the treatment of painful eyes by peribulbar injection of tramadol, clonidine, and ropivacaine.


METHODS
The authors treated a 72-year-old woman with chronic prephthisical pain in the left eye secondary to graft rejection after penetrating keratoplasty and an 81-year-old woman with severe ocular pain in her left eye for neovascular glaucoma secondary to an ischemic central vein occlusion. They were treated with a medial canthus injection of tramadol (100 mg/2 mL ampules), clonidine (0.15 mg/1 mL ampules), and 1% ropivacaine.


RESULTS
Both injections were very well tolerated and neither transient nor lasting complications were reported. Complete pain relief was obtained in both patients within 1 day and was maintained throughout the follow-up (11 months and 7 months).


CONCLUSIONS
Peribulbar tramadol, clonidine, and ropivacaine injection may represent a safe and effective treatment modality in the management of chronic ocular pain.
Department of Ophthalmology, University of Udine, San Daniele, Italy.
A
A
Tarantini
P
P
Lanzetta
U
U
Cugini
D000368:Aged; D000369:Aged, 80 and over; D000577:Amides / Q000627:therapeutic use*; D000700:Analgesics / Q000627:therapeutic use; D000779:Anesthetics, Local / Q000627:therapeutic use; D001766:Blindness / Q000150:complications*; D003000:Clonidine / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D005128:Eye Diseases / Q000188:drug therapy* / Q000209:etiology; D005260:Female; D015355:Glaucoma, Neovascular / Q000209:etiology; D006084:Graft Rejection / Q000209:etiology; D006801:Humans; D007267:Injections; D015948:Keratoplasty, Penetrating / Q000009:adverse effects; D009915:Orbit; D010146:Pain / Q000188:drug therapy* / Q000209:etiology; D012170:Retinal Vein Occlusion / Q000150:complications; D000077212:Ropivacaine; D014147:Tramadol / Q000627:therapeutic use*
D000577:Amides; D000700:Analgesics; D000779:Anesthetics, Local; D014147:Tramadol; D000077212:Ropivacaine; D003000:Clonidine