Inflammatory myopathy with anti-Golgi antibody and anti-SS-A/Ro antibody.
We report a 74-year-old woman with anit-Golgi antibody and anti-SS-A/Ro antibody who contracted inflammatory myopahy presenting 'ALS-like' symptoms. We identified anti-Golgi antibody directly using confocal microscopy and successfully treated her with steroid. This report suggests that there is a new categorized subgroup of inflammatory myopathy with these specific antibodies and the pattern of autoantibody in these patients indicates the specific clinical course and treatment strategy.
Hattori
Hidenori
H
Department of Neurology, Keio University School of Medicine, Tokyo. hidehatt@1999.jukuin.keio.ac.jp
Nagata
Eiichiro
E
Ishihara
Tadayuki
T
Jinnouchi
Kiyo
K
Ogawa
Yoko
Y
Nagai
Toshihiro
T
Suzuki
Shigeaki
S
Shimizu
Toshihiko
T
Hamada
Junichi
J
Suzuki
Norihiro
N
D000368:Aged; D000974:Antibodies, Antinuclear / Q000032:analysis* / Q000276:immunology; D001324:Autoantigens / Q000276:immunology*; D005260:Female; D006056:Golgi Apparatus / Q000276:immunology; D006801:Humans; D018613:Microscopy, Confocal; D009220:Myositis / Q000276:immunology*
D000974:Antibodies, Antinuclear; D001324:Autoantigens; C035356:SS-A antibodies