The relationship between BNP and E/Ea in patients hospitalized with acute heart failure.
BNP and echocardiographic E/Ea are variables helpful in the management of patients with heart failure (HF). The response of E/Ea to treatment for acute decompensated HF remains uncertain. This pilot study aimed to explore this relationship. 24 patients (17 male, mean age 69 years, median ejection fraction 26%) hospitalized with HF were enrolled in this study. Paired clinical examination, BNP-32 level, and echocardiogram were performed at admission and discharge. By discharge patient symptoms and BNP-32 had significantly improved, however E/Ea did not change. Our data suggests that BNP-32 and E/Ea may not be interchangeable indices and may respond differently during treatment of acute decompensated HF.
Cara A
CA
Wasywich
Gillian A
GA
Whalley
Helen A
HA
Walsh
Greg D
GD
Gamble
Robert N
RN
Doughty
D000208:Acute Disease; D000368:Aged; D015150:Echocardiography, Doppler / Q000379:methods / Q000592:standards; D005260:Female; D006333:Heart Failure / Q000097:blood* / Q000175:diagnosis / Q000000981:diagnostic imaging*; D006760:Hospitalization / Q000639:trends*; D006801:Humans; D008297:Male; D020097:Natriuretic Peptide, Brain / Q000097:blood*; D010865:Pilot Projects; D013318:Stroke Volume / Q000502:physiology
D020097:Natriuretic Peptide, Brain