Using homologous recombination to manipulate the genome of human somatic cells.
Porteus
Matthew
M
Departments of Pediatrics and Biochemistry, UT Southwestern Medical Center Dallas, TX 75214, USA. matthew.porteus@utsouthwestern.edu
D000818:Animals; D053903:DNA Breaks, Double-Stranded; D000229:Dependovirus / Q000235:genetics; D018390:Gene Targeting; D005818:Genetic Engineering; D015894:Genome, Human; D023281:Genomics / Q000379:methods; D006801:Humans; D008957:Models, Genetic; D011995:Recombination, Genetic; D012441:Saccharomyces cerevisiae / Q000235:genetics; D016335:Zinc Fingers / Q000235:genetics