Enantioselective Henry reaction catalyzed by a C2-symmetric bis(oxazoline)-Cu(OAc)2.H2O complex.
A C(2)-symmetric diethyl (i)Pr-bis(oxazoline)-Cu(OAc)(2).H(2)O was found to be an efficient catalyst for catalyzing an enantioselective Henry reaction between nitromethane and various aldehydes to provide beta-hydroxy nitroalkanes with high chemical yields (up to 95%) and enantiomeric excesses (up to 97%).
Department of Chemistry, Indian Institute of Technology Kanpur, India 208 016.
Sandeep K
SK
Ginotra
Vinod K
VK
Singh