Alkane hydroxylation by a nonheme iron catalyst that challenges the heme paradigm for oxygenase action.
A nonheme iron catalyst catalyzed stereoselective oxidation of alkanes with H2O2 with remarkable efficiency and exhibiting an unprecedented high incorporation of water into the oxidized products. The present results challenge the canonical description of oxygenases, the standard oxo-hydroxo tautomerism that applies to heme systems and serves as a precedent for alternative pathways for the oxidation of hydrocarbons at nonheme iron oxygenases.
Departament de Química and Institut de Química Computacional, Campus de Montilivi, Universitat de Girona, E-17071 Girona, Spain.
Anna
A
Company
Laura
L
Gómez
Mireia
M
Güell
Xavi
X
Ribas
Josep M
JM
Luis
Lawrence
L
Que
Miquel
M
Costas
D000473:Alkanes / Q000737:chemistry*; D002384:Catalysis; D006418:Heme / Q000737:chemistry*; D006900:Hydroxylation; D007501:Iron / Q000737:chemistry*; D010084:Oxidation-Reduction; D010105:Oxygenases / Q000737:chemistry*; D013237:Stereoisomerism
D000473:Alkanes; D006418:Heme; D007501:Iron; D010105:Oxygenases