Inflammatory myopathy with anti-Golgi antibody and anti-SS-A/Ro antibody.
We report a 74-year-old woman with anit-Golgi antibody and anti-SS-A/Ro antibody who contracted inflammatory myopahy presenting 'ALS-like' symptoms. We identified anti-Golgi antibody directly using confocal microscopy and successfully treated her with steroid. This report suggests that there is a new categorized subgroup of inflammatory myopathy with these specific antibodies and the pattern of autoantibody in these patients indicates the specific clinical course and treatment strategy.
Department of Neurology, Keio University School of Medicine, Tokyo. hidehatt@1999.jukuin.keio.ac.jp
Hidenori
H
Hattori
Eiichiro
E
Nagata
Tadayuki
T
Ishihara
Kiyo
K
Jinnouchi
Yoko
Y
Ogawa
Toshihiro
T
Nagai
Shigeaki
S
Suzuki
Toshihiko
T
Shimizu
Junichi
J
Hamada
Norihiro
N
Suzuki
D000368:Aged; D000974:Antibodies, Antinuclear / Q000032:analysis* / Q000276:immunology; D001324:Autoantigens / Q000276:immunology*; D005260:Female; D006056:Golgi Apparatus / Q000276:immunology; D006801:Humans; D018613:Microscopy, Confocal; D009220:Myositis / Q000276:immunology*
D000974:Antibodies, Antinuclear; D001324:Autoantigens; C035356:SS-A antibodies