Neural correlates of musicogenic epilepsy: SISCOM and FDG-PET.
To localize the neural correlates of musicogenic epilepsy, subtraction ictal SPECT coregistered with MRI (SISCOM) and (18)F-fluorodeoxy glucose positron emission tomography (FDG-PET) were performed in a woman who had suffered from frequent musicogenic seizures. She had complex partial seizures consisting of palpitation and an unpleasant feeling, which were followed by staring and oroalimentary automatisms. Ictal EEG showed rhythmic theta waves originated from the right temporal lobe, and SISCOM showed ictal hyperperfusion on right insula, amygdala, hippocampal head, and anterior temporal lobe, whereas interictal FDG-PET showed interictal hypometabolism in the same brain regions, suggesting dysfunction and abnormal activation of right temporo-limbic structures related to an emotional response to music.
Cho
Jae-Wook
JW
Department of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Irwon-dong, Gangnam-gu, Seoul 135-710, Republic of Korea.
Seo
Dae Won
DW
Joo
Eun Yeon
EY
Tae
Woo Suk
WS
Lee
Jihyun
J
Hong
Seung Bong
SB
D000328:Adult; D001923:Brain Chemistry / Q000502:physiology; D004569:Electroencephalography; D017029:Epilepsy, Complex Partial / Q000000981:diagnostic imaging / Q000503:physiopathology; D020195:Epilepsy, Reflex / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008279:Magnetic Resonance Imaging; D019275:Radiopharmaceuticals; D015899:Tomography, Emission-Computed, Single-Photon
D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18