Application of proteomic technology in eye research: a mini review.
Proteomics is a rapidly growing research area for the study of the protein cognate of genomic data. This review gives a brief overview of the modern proteomic technology. In addition to general applications of proteomics, we highlight its contribution to studying the physiology of different ocular tissues. We also summarise the published proteomic literature in the broad context of ophthalmic diseases, such as cataract, age-related maculopathy, diabetic retinopathy, glaucoma and myopia. The proteomic technology is a useful research tool and it will continue to advance our understanding of a variety of molecular processes in ocular tissues and diseases.
Lam
Thomas C
TC
Laboratory of Experimental Optometry, Centre for Myopia Research, School of Optometry, The Hong Kong Polytechnic University, Hong Kong SAR, China.
Chun
Rachel K M
RK
Li
King-Kit
KK
To
Chi-Ho
CH
D005128:Eye Diseases / Q000175:diagnosis / Q000235:genetics*; D005136:Eye Proteins / Q000032:analysis* / Q000235:genetics; D015894:Genome, Human; D006801:Humans; D040901:Proteomics / Q000379:methods*
D005136:Eye Proteins