[Decrease of serum cholinesterase in colorectal cancer].
OBJECTIVE
Cholinesterase is an enzyme with an unknown physiologic function. Some situations are related to a decreased serum cholinesterase activity but those situations are not well defined and the responsible mechanisms are unknown. Malignancy is one of these situations. The aim of the study was to compare the cholinesterase activity between patients with and without colorectal cancer.


METHODS
Case-control study of patients with colorectal cancer who underwent surgery in our hospital from March 05 to January 07.


RESULTS
Patients from the cancer group had a significant decreased serum cholinesterase activity.


CONCLUSIONS
Investigation of cholinesterase function in humans may result in new research lines in oncology treatment.
Morera Ocón
Francisco J
FJ
Servicio de Cirugía General, Hospital General de Requena, Requena, Valencia, Spain. fmoreraocon@aecirujanos.es
Ripoll Orts
Francisco
F
García-Granero Ximénez
Mario
M
Pastor
María José
MJ
Bernal Sprekelsen
Juan Carlos
JC
D000368:Aged; D016022:Case-Control Studies; D002802:Cholinesterases / Q000097:blood*; D015179:Colorectal Neoplasms / Q000097:blood*; D005260:Female; D006801:Humans; D008297:Male
D002802:Cholinesterases