[Efficiency of antioxidative therapy for acute poisoning by cautery substances].
Analysis of the clinical and laboratory parameters in patients with acute poisoning by cauterants has demonstrated that inclusion of the antioxidant mexidole into the package of therapeutic measures is effective in treating the above pathology. This is supported by the reductions in the proportion of fatal outcomes by more than twice and in the incidence of pneumonia complicating the course of the underlying disease, as well as by the increase in the rate of regeneration of ulceronecrotic defects in the gastrointestinal tract and by the decrease in the number of gastric cicatricial deformities when mexidole is locally used.
Il'iashenko
K K
KK
Luzhnikov
E A
EA
Belova
M V
MV
Nimaev
Zh Ts
ZhTs
Pinchuk
T P
TP
D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000368:Aged; D000975:Antioxidants / Q000008:administration & dosage / Q000627:therapeutic use*; D002057:Burns, Chemical / Q000188:drug therapy* / Q000209:etiology / Q000378:metabolism; D004947:Esophagus / Q000187:drug effects* / Q000293:injuries / Q000378:metabolism; D005753:Gastric Mucosa / Q000378:metabolism; D006801:Humans; D015227:Lipid Peroxidation / Q000187:drug effects; D008875:Middle Aged; D013270:Stomach / Q000187:drug effects* / Q000293:injuries
D000975:Antioxidants