[Drug side effects as the cause of gastrointestinal problems in elderly people].
Adverse drug reactions on the digestive tract are very common. Some special aspects must be heeded, especially in geriatric patients who often take several medications concomitantly. These include a potentially altered drug metabolism, possible lack of compliance, potential drug interactions as a result of polypharmaceutical therapy, the influence of comorbidities as well as the possibility of increased sensitivity and hence, toxic effect on the target organs.
Medizinische Klinik und Poliklinik II, Universitätsklinikum Würzburg. Scheurlen_M@klinik.uni-wuerzburg.de
Michael
M
Scheurlen
D000368:Aged; D056486:Chemical and Drug Induced Liver Injury / Q000175:diagnosis; D003248:Constipation / Q000139:chemically induced; D003967:Diarrhea / Q000139:chemically induced; D004347:Drug Interactions; D004359:Drug Therapy, Combination; D064420:Drug-Related Side Effects and Adverse Reactions; D005767:Gastrointestinal Diseases / Q000139:chemically induced* / Q000175:diagnosis; D006801:Humans; D008111:Liver Function Tests; D010599:Pharmacokinetics; D012307:Risk Factors