High-resolution intermolecular zero-quantum coherence spectroscopy under inhomogeneous fields with effective solvent suppression.
Intermolecular zero-quantum coherences (iZQCs) are not susceptible to magnetic field inhomogeneities significantly larger than the dipolar correlation distance and can be used to obtain 1D high-resolution spectra in an inhomogeneous field. However, with the iZQC methods proposed previously, residual conventional single-quantum coherences (SQCs) originating mainly from solvent resonance result in strong t(1) ridge noises. A modified HOMOGENIZED with an intermolecular double-quantum filter (iDQF), named iDQF-HOMOGENIZED, is presented in this work to suppress the residual conventional SQC signals as well as solvent iZQC signals. The solvent-suppression efficiency of the iDQF-HOMOGENIZED is analyzed and a thorough comparison of the new sequence with several relevant pulse sequences is made. Dramatic resolution enhancement and solvent suppression in the measurements of a piece of grape sarcocarp suggest potential applications of the method in in vivo spectroscopy.
Chen
Xi
X
Department of Physics, State Key Laboratory of Physical Chemistry of Solid Surface, Xiamen University, Xiamen, 361005, PR China.
Lin
Meijin
M
Chen
Zhong
Z
Cai
Shuhui
S
Zhong
Jianhui
J
D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D011789:Quantum Theory; D012997:Solvents / Q000737:chemistry
D012997:Solvents