The post-endodontic periapical lesion: histologic and etiopathogenic aspects.
Apical periodontitis is produced in the majority of cases by intraradicular infection. Treatment consists in the elimination of the infectious agents by endodontia. Even when carrying out a correct cleansing and filling of canals, it is possible that periapical periodontitis will persist in the form of an asymptomatic radiolucency, giving rise to the post-endodontic periapical lesion. The chronic inflammatory periapical lesion is the most common pathology found in relation to alveolar bone of the jaw. From the histological point of view, it can be classified as chronic periapical periodontitis (periapical granuloma), radicular cyst, and as scar tissue. The most frequent is the periapical granuloma, constituted by a mass of chronic inflammatory tissue, in which isolated nests of epithelium can be found. The radicular cyst is characterized by the presence of a cavity, partially or wholly lined by epithelium. Scar tissue is a reparative response by the body, producing fibrous connective tissue. The aim of this study is to review and update the etiopathogenic and histological aspects of chronic post-endodontic periapical lesions.
Valencia University Medical and Dental School, Valencia, Spain.
Celia Carrillo
CC
García
Francisco Vera
FV
Sempere
Miguel Peñarrocha
MP
Diago
Eva Martí
EM
Bowen
D006801:Humans; D010483:Periapical Diseases / Q000209:etiology* / Q000473:pathology*; D012390:Root Canal Therapy / Q000009:adverse effects*