Distribution of hepatitis B virus (HBV) genotypes among HBV carriers in Isparta.
The aim of this study was to investigate the prevalence of hepatitis B virus (HBV) genotypes in Isparta, Southwest of Turkey, as well as the clinical features and transmission route for patients with HBV infections.



Patients (n = 135) with HBV infection were included in the study. Epidemiological and clinical data were obtained. HBV genotypes were determined with a preS2 epitope ELISA kit.



Although the HBV transmission route remained unidentified in 51.1% of the patients, blood contact was determined as the most common probable transmission route (38.5%). One hundred twenty-four (91.8%) of 135 samples, could be genotyped. One hundred fifteen (85.1%) were genotyped as type D/E, six (4.4%) were genotyped as type A, two (1.4%) were genotyped as type C, and one (0.7%) were genotyped as type F.



Genotype D/E is determined as the predominant HBV genotype circulating in Isparta, Southwest of Turkey. No relationship between genotypes and disease severity and transmission route has been detected.
Kaya
Selcuk
S
Suleyman Demirel University, Medical Faculty, Microbiology and Clinical Microbiology Department, Isparta, Turkey.
Cetin
Emel Sesli
ES
Suleyman Demirel University, Medical Faculty, Microbiology and Clinical Microbiology Department, Isparta, Turkey.
Aridogan
Buket Cicioglu
BC
Suleyman Demirel University, Medical Faculty, Microbiology and Clinical Microbiology Department, Isparta, Turkey.
Onal
Süleyman
S
Suleyman Demirel University, Medical Faculty, Microbiology and Clinical Microbiology Department, Isparta, Turkey.
Demirci
Mustafa
M
Suleyman Demirel University, Medical Faculty, Microbiology and Clinical Microbiology Department, Isparta, Turkey.
D000293:Adolescent; D000328:Adult; D000368:Aged; D002353:Carrier State / Q000453:epidemiology / Q000635:transmission / Q000821:virology; D005260:Female; D005787:Gene Frequency; D005838:Genotype; D006509:Hepatitis B / Q000453:epidemiology / Q000635:transmission / Q000821:virology*; D006515:Hepatitis B virus / Q000235:genetics*; D006801:Humans; D008297:Male; D008875:Middle Aged; D014421:Turkey / Q000453:epidemiology