[Efficiency of preemptive intravenous paracetamol analgesia in abdominal surgery].
In a randomized, controlled study, 50 patients underwent elective surgery for abdominal cancer lesions under perioperative epidural analgesia. All the patients were randomized to receive paracetamol in a single intravenous dose of 1 g or placebo 30 minutes prior to the start of surgery. The use of 1 g of paracetamol as a single intravenous preemptive dose in abdominal surgery with perioperative epidural analgesia does not reduce the consumption of the analgesic and the intensity of pain in the postoperative period.
Borisov
D B
DB
Levin
A V
AV
Vyl'iurov
I V
IV
Sokolov
A V
AV
Nedashkovskiĭ
E V
EV
D000082:Acetaminophen / Q000008:administration & dosage / Q000627:therapeutic use*; D015360:Analgesia, Epidural / Q000379:methods; D018712:Analgesics, Non-Narcotic / Q000008:administration & dosage / Q000627:therapeutic use*; D003110:Colonic Neoplasms / Q000601:surgery; D013505:Digestive System Surgical Procedures / Q000379:methods*; D005260:Female; D006801:Humans; D007275:Injections, Intravenous; D008297:Male; D008875:Middle Aged; D010147:Pain Measurement; D010149:Postoperative Pain / Q000517:prevention & control*; D011300:Preoperative Care / Q000379:methods*; D013274:Stomach Neoplasms / Q000601:surgery; D013997:Time Factors
D018712:Analgesics, Non-Narcotic; D000082:Acetaminophen