Lung resection in cystic fibrosis: a survival analysis.
Lung resection may be considered for cystic fibrosis (CF) patients showing localized severe chronic atelectasis and/or bronchiectasis. Nonetheless, literature on survival after surgery is scarce. This study was carried out to assess survival time after partial lung resection. Twenty-one CF patients were operated from 1988 to 2003 and were followed until November 30th, 2004. Survival analysis was performed through Kaplan-Meier method. Mean age at resection was 8.09 years (SD 4.40 years) and two-thirds were females. Z-scores for height, weight, and body mass index as well as FEV1 values showed no statistical significance when comparing values obtained from 2 years before to 2 years after resection. Eleven years after resection, survival probability was 93.8%. Our results suggest that lobectomy or segmentectomy are safe procedures and should be considered in carefully selected patients with unilateral severe symptomatic localized and chronic persistent atelectasis and/or bronchiectasis refractory to conservative management.
Pediatric Pumonology Unit, University Hospital, Federal University of Minas Gerais, Belo Horizonte, Belo Horizonte, Brazil. pcamargs@medicina.ufmg.br
Paulo
P
Camargos
Muriel
M
Le Bourgeois
Yann
Y
Revillon
Edson
E
Tatsuo
Isabelle
I
Sermet-Gaudelus
Pierre
P
Scheinmann
Jacques
J
de Blic
D001987:Bronchiectasis / Q000209:etiology / Q000601:surgery; D002648:Child; D015331:Cohort Studies; D003550:Cystic Fibrosis / Q000150:complications / Q000601:surgery*; D005260:Female; D006801:Humans; D053208:Kaplan-Meier Estimate; D008297:Male; D011013:Pneumonectomy / Q000401:mortality; D001261:Pulmonary Atelectasis / Q000209:etiology / Q000601:surgery; D016019:Survival Analysis; D013997:Time Factors