Stereospecific synthesis of (-)-neplanocin F.
The stereospecific synthesis of (-)-neplanocin F was achieved in 15 steps from 2,3-O-isopropylidene-D-1,4-ribonolactone. The synthetic methodology can give an access through appropriate modifications to new series of carbanucleosides.
UMR 5625 CNRS-UM II, Université Montpellier II, Montpellier, France.
Sergio Rodriguez
SR
Ropero
Dolorès
D
Edmont
Christophe
C
Mathé
Christian
C
Périgaud
D000241:Adenosine / Q000031:analogs & derivatives / Q000138:chemical synthesis / Q000737:chemistry; D008722:Methods; D015394:Molecular Structure; D009705:Nucleosides / Q000138:chemical synthesis / Q000737:chemistry; D013237:Stereoisomerism
D009705:Nucleosides; C031096:neplanocin A; C031300:neplanocin F; D000241:Adenosine