BioSTAR bioabsorbable septal repair implant.
Thousands of patients have had congenital defects of their intra-atrial septa successfully closed via percutaneous techniques in the cardiac catheterization laboratory for hemodynamic correction, stroke, migraine and decompression illness. However, currently available closure technologies leave a permanent cardiac implant in a relatively young patient population. As the first device incorporating a bioabsorbable material for the treatment of structural heart disease, BioSTAR is uniquely designed to remodel into native tissue following closure, providing a more natural method of defect repair. This paper reviews atrial morphology, with a focus on patent foramen ovale, indications both present and emerging, and the development of technologies that promote a healthy natural healing response, with a focus on the design, testing and clinical experience with BioSTAR.
Mullen
Michael J
MJ
Royal Brompton Hospital, Sydney Street, London SW3 6NP, England. m.mullen@rbh.nthames.nhs.uk
Devellian
Carol A
CA
Jux
Christian
C
D020341:Absorbable Implants; D002986:Clinical Trials as Topic; D054092:Foramen Ovale, Patent; D006343:Heart Septal Defects / Q000628:therapy*; D006801:Humans; D014945:Wound Healing