[A case of Epstein-Barr virus (EBV) associated remnant gastric carcinoma arising 7 years after distal gastrectomy for EBV associated gastric carcinoma].
A 52-year-old man undergoing distal gastrectomy for gastric cancer in July 1998 was found to have a 0-IIa type gastric tumor near EC junction in January 2005. Histological examination showed the tumor was moderately differentiated adenocarcinoma. As the tumor was diagnosed as mucosal cancer, endoscopic mucosal dissection was performed. But pathological findings showed the depth of cancer cell invasion into deep submucosal layer. Then total resection of remnant stomach was performed. Both tumors were diagnosed as EBV-associated carcinoma. It is speculated that the mucosa changing after initial operation would give risk to a new occurrence of EBV-associated remnant gastric carcinoma. And then follow up after operation is important. Although some cases of EBV-associated remnant gastric carcinoma is found for short period after the primary surgery, our case second primary cancer was found 7 year after primary surgery. Long term follow-up by Endoscopy seems to be important.
Takahashi
Koichi
K
Department of Gastrointestinal Surgery, Saitama Medical University School of Medicine.
Otani
Yoshihide
Y
Ogawa
Nobuji
N
Yasumoto
Akihiro
A
Takeda
Akihiko
A
Miyazawa
Mitsuo
M
Shinozuka
Nozomi
N
Koyama
Isamu
I
Arai
Shin
S
Ota
Shinichi
S
Ban
Shinichi
S
D000230:Adenocarcinoma / Q000473:pathology* / Q000601:surgery / Q000821:virology*; D005743:Gastrectomy; D018530:Gastric Stump / Q000473:pathology; D004854:Herpesvirus 4, Human / Q000302:isolation & purification*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D013274:Stomach Neoplasms / Q000473:pathology* / Q000601:surgery / Q000821:virology*