[Transfusion-related acute lung injury (TRALI)].
According to data of international hemovigilance registries, transfusion-related acute lung injury (TRALI) has emerged as the leading cause of transfusion-related mortality. Errors in the transfusion process, leading to ABO incompatible transfusion, represent the second most frequent cause of transfusion-related mortality, while infection risks of transfusion declined significantly. The following article describes the clinical picture of TRALI, its pathogenesis, diagnostic criteria as well as therapy recommendations and discusses possible preventing measures.
Institut für Klinische Immunologie und Transfusionsmedizin am Universitätsklinikum Giessen und Marburg GmbH. ulrich.sachs@immunologie.med.uni-giessen.de
Ulrich J H
UJ
Sachs
Gregor
G
Bein
D006801:Humans; D012128:Respiratory Distress Syndrome / Q000175:diagnosis* / Q000209:etiology / Q000517:prevention & control / Q000628:therapy*; D065227:Transfusion Reaction