[Studies on chemical constituents from root of Cynanchum atratum].
OBJECTIVE
To study the chemical constituents from the roots and rhizome of Cynanchum atratum.


METHODS
The chemical constituents were isolated and repeatedly purified by silica gel chromatography and the structures were elucidated by the NMR spectra and physicochemical properties.


RESULTS
Twelve compounds were obtained and nine of them were identified as 2, 4-dihyroxyacetophe none (1), 2, 6-dihyroxyacetophenone (2), 4-hydroxybenzenemethanol (3), benzoic acid (4), beta-amyrin acetate (5), palmitic acid (6), beta-sitosterol (7), beta-daucosterol (8), glaucogenin C-3-O-alpha-D-oleandropyranosyl-(1 --> 4)-beta-D-digitoxopyranosyl-(1 -->4)-alpha-D-oleandropyranoside (9).


CONCLUSIONS
Seven compounds were obtained from C. atratum for the first time.
Yuan
Ying
Y
School of Pharmacy, Shanghai Jiaotong University, Shanghai 200240, China.
Zhang
Wei-Dong
WD
Zhang
Chuan
C
Liu
Run-Hui
RH
Su
Juan
J
Jin
Hui-Zi
HZ
D019817:Benzoic Acid / Q000737:chemistry / Q000302:isolation & purification*; D002850:Chromatography, Gel; D031105:Cynanchum / Q000737:chemistry*; D009828:Oleanolic Acid / Q000031:analogs & derivatives* / Q000737:chemistry / Q000302:isolation & purification; D019308:Palmitic Acid / Q000737:chemistry / Q000302:isolation & purification*; D018517:Plant Roots / Q000737:chemistry*; D010946:Plants, Medicinal / Q000737:chemistry; D058428:Silica Gel; D012822:Silicon Dioxide
D019308:Palmitic Acid; D058428:Silica Gel; D009828:Oleanolic Acid; D012822:Silicon Dioxide; D019817:Benzoic Acid; C000265:beta-amyrin acetate