Emergency management of upper airway angio-oedema after routine dental extraction in a patient with C1 esterase deficiency.
Hereditary angio-oedema is rare and potentially life-threatening, being characterised by recurrent episodes of perioral or laryngeal oedema. We describe a 28-year-old woman who developed stridor, orofacial swelling, and drooling several hours after a routine dental extraction. This was initially diagnosed as a spreading dental infection. Only after early oral and maxillofacial review and taking a thorough family history was C1 esterase-inhibitor deficiency diagnosed. She was immediately given C1 esterase-inhibitor concentrate, made a complete recovery and was discharged next day.
Oral and Maxillofacial Surgery, Barts and the Royal London NHS Trust, Whitechapel, London, E1 1BB, United Kingdom. scott.rice@virgin.net
S
S
Rice
T J
TJ
Cochrane
M
M
Millwaters
N T
NT
Ali
D000328:Adult; D054179:Angioedemas, Hereditary / Q000188:drug therapy* / Q000209:etiology; D050718:Complement C1 Inhibitor Protein / Q000627:therapeutic use*; D004638:Emergency Treatment; D005260:Female; D006801:Humans; D014081:Tooth Extraction / Q000009:adverse effects*
D050718:Complement C1 Inhibitor Protein