Revisited 3'-deoxy-3'-C-methyl-beta-D-ribonucleoside series.
The synthesis of some 3'-deoxy-3'-C-methylnucleoside analogues bearing naturally occuring nucleic acid bases was achieved from the preparation of a suitable peracylated 3-deoxy-3-C-methyl sugar using a stereoselective pathway. In addition, examples of chemical modifications at the 2' position are presented.
UMR 5625 CNRS-UM II, Université Montpellier II, Montpellier, France.
Mohamed
M
Aljarah
Sarah
S
Couturier
Gilles
G
Gosselin
Christophe
C
Mathé
Christian
C
Périgaud
D000998:Antiviral Agents / Q000138:chemical synthesis / Q000737:chemistry; D003853:Deoxyribonucleosides / Q000138:chemical synthesis* / Q000737:chemistry*; D015195:Drug Design; D006031:Glycosylation; D008745:Methylation; D013237:Stereoisomerism
D000998:Antiviral Agents; D003853:Deoxyribonucleosides