Methadone-induced QTc prolongation: is it due to stereoselective block of hERG or to inappropriate QT interval correction?
G
G
Andrássy
A
A
Szabo
D000072237:ERG1 Potassium Channel; D004562:Electrocardiography / Q000187:drug effects*; D051638:Ether-A-Go-Go Potassium Channels / Q000037:antagonists & inhibitors*; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D008691:Methadone / Q000494:pharmacology*; D013237:Stereoisomerism; D013379:Substrate Specificity
D000072237:ERG1 Potassium Channel; D051638:Ether-A-Go-Go Potassium Channels; C000606913:KCNH2 protein, human; D008691:Methadone