Dendroscope: An interactive viewer for large phylogenetic trees.
BACKGROUND
Research in evolution requires software for visualizing and editing phylogenetic trees, for increasingly very large datasets, such as arise in expression analysis or metagenomics, for example. It would be desirable to have a program that provides these services in an efficient and user-friendly way, and that can be easily installed and run on all major operating systems. Although a large number of tree visualization tools are freely available, some as a part of more comprehensive analysis packages, all have drawbacks in one or more domains. They either lack some of the standard tree visualization techniques or basic graphics and editing features, or they are restricted to small trees containing only tens of thousands of taxa. Moreover, many programs are difficult to install or are not available for all common operating systems.


RESULTS
We have developed a new program, Dendroscope, for the interactive visualization and navigation of phylogenetic trees. The program provides all standard tree visualizations and is optimized to run interactively on trees containing hundreds of thousands of taxa. The program provides tree editing and graphics export capabilities. To support the inspection of large trees, Dendroscope offers a magnification tool. The software is written in Java 1.4 and installers are provided for Linux/Unix, MacOS X and Windows XP.


CONCLUSIONS
Dendroscope is a user-friendly program for visualizing and navigating phylogenetic trees, for both small and large datasets.
Center for Bioinformatics Tübingen (ZBIT), Eberhard-Karls-Universität Tübingen, Sand 14, 72076 Tübingen, Germany. huson@informatik.uni-tuebingen.de
Daniel H
DH
Huson
Daniel C
DC
Richter
Christian
C
Rausch
Tobias
T
Dezulian
Markus
M
Franz
Regula
R
Rupp
D005075:Biological Evolution; D003196:Computer Graphics; D003198:Computer Simulation; D003628:Database Management Systems; D030541:Databases, Genetic; D016247:Information Storage and Retrieval / Q000379:methods; D008957:Models, Genetic; D010375:Pedigree; D010802:Phylogeny; D012984:Software; D014584:User-Computer Interface