Cortical silent period following TMS in a patient with supplementary sensorimotor area seizures.
The cortical silent period (CSP) following transcranial magnetic stimulation (TMS) was evaluated in a patient with a dysembrioplastic neuroepithelial tumor (DNET) in the lateral portion of the right superior frontal gyrus (SFG) who suffered from supplementary sensorimotor area (SSMA) seizures. CSP duration was shortened on the affected side. Ipsilateral alterations of motor cortex excitability with TMS in epileptogenic DNET located outside the PMA argue in favour of cortico-cortical connections to primary motor cortex from SSMA. This functional connectivity should be taken into consideration to better understand the pathophysiology of ictal motor manifestations.
Department of Neurology, Franz.Tappeiner Hospital, Via Rossini, 5, 39012, Merano, Italy. raffaele.nardone@asbmeran-o.it
Raffaele
R
Nardone
Alessandro
A
Venturi
Harald
H
Ausserer
Günther
G
Ladurner
Frediano
F
Tezzon
D000328:Adult; D001931:Brain Mapping / Q000379:methods; D001932:Brain Neoplasms / Q000150:complications / Q000473:pathology; D004568:Electrodiagnosis / Q000379:methods; D004827:Epilepsy / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology*; D005071:Evoked Potentials; D005625:Frontal Lobe / Q000473:pathology / Q000503:physiopathology*; D006801:Humans; D008297:Male; D009044:Motor Cortex / Q000473:pathology / Q000503:physiopathology*; D018302:Neoplasms, Neuroepithelial / Q000150:complications / Q000473:pathology; D009433:Neural Inhibition; D009434:Neural Pathways / Q000473:pathology / Q000503:physiopathology; D011930:Reaction Time; D013724:Teratoma / Q000150:complications / Q000473:pathology; D013997:Time Factors; D050781:Transcranial Magnetic Stimulation / Q000379:methods*