Myeloid leukemia in children 4 years or older with Down syndrome often lacks GATA1 mutation and cytogenetics and risk of relapse are more akin to sporadic AML.
Hasle
H
H
Abrahamsson
J
J
Arola
M
M
Karow
A
A
O'Marcaigh
A
A
Reinhardt
D
D
Webb
D K H
DK
van Wering
E
E
Zeller
B
B
Zwaan
C M
CM
Vyas
P
P
D002648:Child; D002675:Child, Preschool; D002869:Chromosome Aberrations; D004314:Down Syndrome / Q000235:genetics*; D050982:GATA1 Transcription Factor / Q000235:genetics*; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000235:genetics*; D009154:Mutation; D012008:Recurrence; D012306:Risk
D050982:GATA1 Transcription Factor; C494688:GATA1 protein, human