Assessment of left ventricular dyssynchrony in patients with heart failure and normal QRS duration.
Cardiac resynchronization therapy (CRT) is an important component of heart failure therapy in patients with a left ventricular ejection fraction <35%, class III or ambulatory class IV symptoms, and a QRS duration >120 ms. The QRS duration criterion for patient selection is imperfect. About 30% of patients with an increased QRS duration are nonresponders to CRT and many with a normal QRS duration with mechanical dyssynchrony respond to CRT. The authors review the currently available echocardiographic tools for the assessment of ventricular dyssynchrony in patients with heart failure.
Narayan
Vidya
V
Division of Cardiology, University of Southern California-Keck School of Medicine, Los Angeles, CA, USA.
Varadarajan
Padmini
P
Pai
Ramdas G
RG
D004562:Electrocardiography / Q000379:methods; D006333:Heart Failure / Q000150:complications*; D006801:Humans; D018487:Ventricular Dysfunction, Left / Q000150:complications / Q000175:diagnosis* / Q000503:physiopathology / Q000628:therapy*