Upregulation of multidrug resistance-associated protein 3 by acetaminophen may help to increase its own clearance.
Ghanem
C I
CI
Mottino
A D
AD
D000082:Acetaminophen / Q000008:administration & dosage / Q000494:pharmacology*; D018712:Analgesics, Non-Narcotic / Q000494:pharmacology; D000818:Animals; D004334:Drug Administration Schedule; D051147:Ganglioside Galactosyltransferase / Q000096:biosynthesis / Q000378:metabolism*; D006801:Humans; D027425:ATP-Binding Cassette, Sub-Family C Proteins / Q000187:drug effects* / Q000378:metabolism*; D051381:Rats; D015854:Up-Regulation / Q000187:drug effects
D000082:Acetaminophen; D018712:Analgesics, Non-Narcotic; D051147:Ganglioside Galactosyltransferase; D027425:ATP-Binding Cassette, Sub-Family C Proteins; C114462:multidrug resistance-associated protein 3; C511215:Ugt8 protein, rat