Fractional flow reserve--the influence of the collateral circulation.
Fractional flow reserve (FFR) is a widely used invasive index of coronary artery stenosis. FFR is not influenced by haemodynamic parameters (such as blood pressure and pulse rate) or by the vessel studied. However, true FFR value may be influenced by the presence of major collateral vessels. In this article we describe a case demonstrating this observation and discuss a potential physiological mechanism to account for this finding.
Melikian
Narbeh
N
Cuisset
Thomas
T
Hamilos
Michalis
M
De Bruyne
Bernard
B
D000368:Aged; D015906:Angioplasty, Balloon, Coronary; D003097:Collateral Circulation / Q000502:physiology*; D023921:Coronary Stenosis / Q000503:physiopathology / Q000628:therapy; D003924:Diabetes Mellitus, Type 2 / Q000503:physiopathology; D003925:Diabetic Angiopathies / Q000503:physiopathology / Q000628:therapy; D053805:Fractional Flow Reserve, Myocardial / Q000502:physiology*; D006801:Humans; D008297:Male