[Vaccines, immunoglobulins, and test systems for the prevention and diagnosis of tick-borne encephalitis].
The quality of drugs used in the Russian Federation to prevent and diagnose tick-borne encephalitis (TBE) was analyzed. The TBE vaccines made in Russian were shown to be as effective as those manufactured in foreign countries and to have the similar production techniques and quality indices therefore they may be interchangeable in the population's vaccination. The specific activity of has recently increased in terms of the content of TBE virus antibodies. In Russia, a wide range of enzyme immunoassay systems have been designed and manufactured for the detection of human serum (plasma) IgM and IgG antibodies to TVE virus and for that of TBE viral antigen in the biological objects, primarily in the ticks.
M S
MS
Vorob'eva
M N
MN
Rasshchepkina
I P
IP
Ladyzhenskaia
D000818:Animals; D000914:Antibodies, Viral / Q000097:blood; D000956:Antigens, Viral / Q000097:blood; D004669:Encephalitis Viruses, Tick-Borne / Q000276:immunology* / Q000302:isolation & purification; D004675:Encephalitis, Tick-Borne / Q000097:blood / Q000175:diagnosis* / Q000628:therapy*; D006801:Humans; D007124:Immunoenzyme Techniques / Q000592:standards; D007074:Immunoglobulin G / Q000097:blood; D007075:Immunoglobulin M / Q000097:blood; D007136:Immunoglobulins; D018884:Ixodes / Q000821:virology; D011786:Quality Control; D011933:Reagent Kits, Diagnostic / Q000592:standards*; D012426:Russia; D012680:Sensitivity and Specificity; D015164:Vaccines, Inactivated / Q000276:immunology / Q000592:standards; D014765:Viral Vaccines / Q000276:immunology / Q000592:standards*
D000914:Antibodies, Viral; D000956:Antigens, Viral; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D007136:Immunoglobulins; D011933:Reagent Kits, Diagnostic; D015164:Vaccines, Inactivated; D014765:Viral Vaccines