[Positively charged acyl derivatives of carbohydrates as promising transfection agents].
A convenient approach to the synthesis of mono- and polycationic glycolipid amphiphiles is suggested. The compounds obtained can be used for study of the structure-activity relationship and determination of the effect of hydrophobic and cationic domains on transfection efficiency.
Maslov
M A
MA
Al' Shoéibi
Z Ia
ZIa
Andriushina
T V
TV
Morozova
N G
NG
Serebrennikova
G A
GA
D000215:Acylation; D000818:Animals; D002241:Carbohydrates / Q000138:chemical synthesis / Q000737:chemistry; D006017:Glycolipids / Q000138:chemical synthesis / Q000737:chemistry*; D008081:Liposomes / Q000737:chemistry; D011073:Polyamines / Q000138:chemical synthesis / Q000737:chemistry*; D000071228:Polyelectrolytes; D014162:Transfection
D002241:Carbohydrates; D006017:Glycolipids; D008081:Liposomes; D011073:Polyamines; D000071228:Polyelectrolytes