Noninvasive markers of eosinophilic esophagitis.
There has been an increasing awareness and recognition of eosinophilic esophagitis (EE), a chronic condition with periods of exacerbation and remission, over the last decade. The complex pathophysiology of EE and eosinophil physiology provide several candidate biomarkers that could be studied on various noninvasively obtained body specimens. This article reviews several potential noninvasive biomarkers of EE.
Gupta
Sandeep K
SK
Indiana University School of Medicine, James Whitcomb Riley Hospital for Children, 702 Barnhill Drive, ROC 4210, Indianapolis, IN 46202, USA. sgupta@iupui.edu <sgupta@iupui.edu>
D015415:Biomarkers; D018925:Chemokines; D016207:Cytokines; D004802:Eosinophilia / Q000175:diagnosis* / Q000473:pathology; D004804:Eosinophils / Q000473:pathology*; D004941:Esophagitis / Q000175:diagnosis* / Q000503:physiopathology; D004947:Esophagus / Q000473:pathology*; D006801:Humans; D007073:Immunoglobulin E / Q000097:blood; D008407:Mast Cells; D009498:Neurotoxins; D017455:Receptors, IgE
D015415:Biomarkers; D018925:Chemokines; D016207:Cytokines; D009498:Neurotoxins; D017455:Receptors, IgE; D007073:Immunoglobulin E