Atovaquone-statine "double-drugs" with high antiplasmodial activity.
Romeo
Sergio
S
Institute of Medicinal Chemistry Pietro Pratesi, University of Milan, Via Mangiagalli 25, 20133 Milan, Italy. sergio.romeo@unimi.it
Parapini
Silvia
S
Dell'Agli
Mario
M
Vaiana
Nadia
N
Magrone
Pietro
P
Galli
Germana
G
Sparatore
Anna
A
Taramelli
Donatella
D
Bosisio
Enrica
E
D000596:Amino Acids / Q000737:chemistry / Q000494:pharmacology*; D000818:Animals; D000962:Antimalarials / Q000737:chemistry / Q000494:pharmacology*; D053626:Atovaquone / Q000737:chemistry / Q000494:pharmacology*; D004351:Drug Resistance / Q000187:drug effects* / Q000502:physiology; D006863:Hydrogen-Ion Concentration; D010963:Plasmodium falciparum / Q000187:drug effects* / Q000378:metabolism; D013329:Structure-Activity Relationship
D000596:Amino Acids; D000962:Antimalarials; D053626:Atovaquone; C013165:statine