Assessing transient cross-frequency coupling in EEG data.
Synchronization of oscillatory EEG signals across different frequency bands is receiving waxing interest in cognitive neuroscience and neurophysiology, and cross-frequency coupling is being increasingly linked to cognitive and perceptual processes. Several methods exist to examine cross-frequency coupling, although each has its limitations, typically by being flexible only over time or over frequency. Here, a method for assessing transient cross-frequency coupling is presented, which allows one to test for the presence of multiple, dynamic, and flexible cross-frequency coupling structure over both time and frequency. The method is applied to intracranial EEG data, and strong coupling between gamma ( approximately 40-80 Hz) and upper theta ( approximately 7-9 Hz) was observed. This method might have useful applications in uncovering the electrophysiological correlates of cognitive processes.
Department of Epileptology and Center for Life and Brain, University of Bonn, Germany. mikexcohen@gmail.com
Michael X
MX
Cohen
D000328:Adult; D000465:Algorithms; D003071:Cognition / Q000502:physiology; D003627:Data Interpretation, Statistical; D004567:Electrodes, Implanted; D004569:Electroencephalography / Q000706:statistics & numerical data*; D004827:Epilepsy / Q000503:physiopathology; D006801:Humans; D008297:Male; D010465:Perception / Q000502:physiology; D013826:Theta Rhythm / Q000706:statistics & numerical data