[Leptin, leptin gene, leptin gene receptor polymorphisms and pregnancy].
The article presents information about leptin as the major metabolic hormone. The structure, localization of the hormone and its receptor have been described focusing on maturation and fertility processes. Several polymorphisms of leptin gene and its receptor have been described as potential developmental factors of pregnancy complications such as diabetes mellitus or pregnancy induced hypertension.
Iciek
Rafał
R
Klinika Połoznictwa i Chorób Kobiecych Uniwersytetu Medycznego w Poznaniu. kpichk@gpsk.am.poznan.pl
Wender-Ozegowska
Ewa
E
Seremak-Mrozikiewicz
Agnieszka
A
Drews
Krzysztof
K
Brazert
Jacek
J
D016640:Diabetes, Gestational / Q000235:genetics*; D005260:Female; D006801:Humans; D046110:Hypertension, Pregnancy-Induced / Q000235:genetics*; D020738:Leptin / Q000378:metabolism*; D011110:Polymorphism, Genetic; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000235:genetics*; D054411:Receptors, Leptin / Q000235:genetics*
C515448:LEPR protein, human; D020738:Leptin; D054411:Receptors, Leptin