Recordings of the optical intrinsic signal from the middle turbinate in response to olfactory and trigeminal stimulation: a pilot study.
Responses from the middle turbinate elicited by olfactory and trigeminal stimuli were studied using the intrinsic optical signal (IOS) recording technique. Nasal cavity was illuminated by 617 nm light. Olfactory (H2S) or trigeminal (CO2) stimuli of 5-s duration were presented using a computer-controlled olfactometer; IOS responses were captured by a special camera. Averages across five individual IOS recordings were analyzed. When the nasal cavity was exposed to H2S, a significant change of the IOS was found; responses to CO2 were even more pronounced. The present results argue for the idea that the IOS is an indicator of intranasal chemosensory activation.
Department of Otorhinolaryngology, Smell and Taste Clinic, University of Dresden Medical School (Technische Universität Dresden), Dresden, Germany. taishimaru-alg@umin.ac.jp
Tadashi
T
Ishimaru
Mandy
M
Scheibe
Volker
V
Gudziol
Simona
S
Negoias
D000328:Adult; D002245:Carbon Dioxide; D005260:Female; D006801:Humans; D008297:Male; D009296:Nasal Cavity / Q000294:innervation*; D009297:Nasal Mucosa / Q000502:physiology; D009812:Odorants; D009832:Olfactory Nerve / Q000502:physiology*; D010775:Photic Stimulation / Q000295:instrumentation*; D010812:Physical Stimulation / Q000295:instrumentation; D012903:Smell / Q000502:physiology; D013447:Sulfites; D014276:Trigeminal Nerve / Q000502:physiology*; D014420:Turbinates / Q000294:innervation*
D013447:Sulfites; D002245:Carbon Dioxide; C042345:hydrogen sulfite