Identification of beta-lactamase in antibiotic-resistant Bacillus cereus spores.
Beta-lactamase type I is reported for the first time to occur in the sporulated form in a penicillin-resistant Bacillus species. The enzyme was readily characterized from the B. cereus 5/B line (ATCC 13061) by mass spectrometry and two-dimensional gel electrophoresis.
Fenselau
Catherine
C
Department of Chemistry and Biochemistry, University of Maryland, College Park, MD 20742, USA. fenselau@umd.edu
Havey
Crystal
C
Teerakulkittipong
Nuttinee
N
Swatkoski
Stephen
S
Laine
Olli
O
Edwards
Nathan
N
D000595:Amino Acid Sequence; D001409:Bacillus cereus / Q000187:drug effects / Q000201:enzymology* / Q000502:physiology*; D015180:Electrophoresis, Gel, Two-Dimensional; D013058:Mass Spectrometry; D008969:Molecular Sequence Data; D010403:Penicillin Resistance; D010405:Penicillinase / Q000737:chemistry / Q000235:genetics / Q000378:metabolism; D011498:Protein Precursors / Q000737:chemistry / Q000378:metabolism; D013171:Spores, Bacterial / Q000187:drug effects / Q000201:enzymology*; D001618:beta-Lactamases / Q000737:chemistry / Q000235:genetics / Q000378:metabolism
D011498:Protein Precursors; D010405:Penicillinase; D001618:beta-Lactamases