Nucleophilic activity of a linked bis{guanidine} leading to formation of a dicationic C4N4-heterocycle.
The methylene-linked bis{guanidine}, H(2)C{hpp}(2) (hppH = 1,3,4,6,7,8-hexahydro-2H-pyrimido[1,2-a]pyrimidine), displays nucleophilic activity towards organic halides, including the activation of dichloromethane under ambient conditions affording the cyclic dication, [H(2)C{hpp}(2)CH(2)](2+)[Cl](2).
Department of Chemistry, University of Sussex, Falmer, Brighton, UK BN1 9QJ. m.p.coles@sussex.ac.uk
Martyn P
MP
Coles
Steven F
SF
Lee
Sarah H
SH
Oakley
Guillermina
G
Estiu
Peter B
PB
Hitchcock