[Comparison of granisetron and metoclopramide for prevention of nausea and vomiting following total cystectomy and ileal conduit].
The objective of this study was to examine the use of granisetron in actual clinical practice and to compare effect of dose of 1 mg granisetron after total cystectomy plus ileal conduit with group of patients which received metoclopramide. Granisetron established total contol of PONV in 93,33% patients. Granisetron is 40% more effective in PONV control than metoclopramide. Only minimal nausea epizodes were observed in early postoperative period in patients who had received low dose of granisetron (1 mg i.v.).
Institut za anesteziju i reanimaciji, KCS, Beograd.
N
N
Ladjević
I
I
Likić Ladjević
B
B
Krivić
J
J
Filimonović
M
M
Aćimović
D
D
Dragićević
R
R
Argirović
D000932:Antiemetics / Q000627:therapeutic use*; D015653:Cystectomy; D017829:Granisetron / Q000627:therapeutic use*; D006801:Humans; D008787:Metoclopramide / Q000627:therapeutic use*; D008875:Middle Aged; D020250:Postoperative Nausea and Vomiting / Q000517:prevention & control*; D014547:Urinary Diversion
D000932:Antiemetics; D017829:Granisetron; D008787:Metoclopramide