[Neoadjuvant and adjuvant chemotherapy with methotrexate, cisplatin and bleomycin for advanced penile cancer: a case report].
A 58-year-old male consulted our hospital because of penile swelling and pain with bilateral inguinal lymphadenopathy. Pathological examination of the penile tumor and right superficial inguinal lymph node biopsy demonstrated moderately differentiated squamous cell carcinoma with lymph node metastasis. We diagnosed the tumor inoperable radically and adjuvant chemotherapy with methotrexate, cisplatin and bleomycin was administered, followed by partial penectomy and left superficial lymphadenectomy. The surgical specimens showed few viable tumor cells. This combination chemotherapy is suggested to be effective for the treatment of advanced penile cancer.
Yumura
Yasushi
Y
Department of Urology, Yokohama Municipal Citizen's Hospital.
Takase
Kazunori
K
Suwa
Hiroshi
H
Ohta
Junichi
J
Ueki
Tei-ichiro
T
Kawai
Masaki
M
Fujikawa
Atsushi
A
Yokomizo
Yumiko
Y
Moriyama
Masatoshi
M
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001761:Bleomycin / Q000008:administration & dosage; D002294:Carcinoma, Squamous Cell / Q000556:secondary / Q000628:therapy*; D017024:Chemotherapy, Adjuvant; D002945:Cisplatin / Q000008:administration & dosage; D018572:Disease-Free Survival; D006801:Humans; D008197:Lymph Node Excision; D008207:Lymphatic Metastasis; D008297:Male; D008727:Methotrexate / Q000008:administration & dosage; D008875:Middle Aged; D020360:Neoadjuvant Therapy; D009367:Neoplasm Staging; D010412:Penile Neoplasms / Q000473:pathology / Q000628:therapy*; D010413:Penis / Q000601:surgery*; D016896:Treatment Outcome; D013521:Urologic Surgical Procedures, Male
D001761:Bleomycin; D002945:Cisplatin; D008727:Methotrexate