[Diffuse large B-cell lymphoma initially manifested by massive ascites and a small gastric lesion, clinically mimicking primary effusion lymphoma (PEL) in the abdominal cavity: a case report and review of the literature on Japanese PEL patients].
A 50-year-old man was admitted because of increasing massive ascites. While lymphoma cells (diffuse large B-cell lymphoma: DLBCL) were detected in the ascites, pleural effusion, cerebrospinal fluid and bone marrow, no tumor masses other than a submucosal lymphoma lesion in the stomach only 1 cm in diameter were identified. The patient was treated with chemotherapy including rituximab (R-CHOP-ESHAP) and injection of methotrexate and dexamethasone into the medullary cavity as well as radiation to the whole brain, and achieved complete remission 4 months later. The present case suggests that DLBCL can initially manifest as a form of effusion lymphoma with minimum solid tumor component. The distinctive clinical features of Japanese patients with primary effusion lymphoma are also reviewed.
Zenda
Takahiro
T
Department of Internal Medicine, Kanazawa Social Insurance Hospital.
Tominaga
Kei
K
Choto
Syuichi
S
Okada
Toshihide
T
Kaneko
Syuichi
S
Minato
Hiroshi
H
D001201:Ascites / Q000150:complications; D003937:Diagnosis, Differential; D006801:Humans; D016403:Lymphoma, Large B-Cell, Diffuse / Q000175:diagnosis*; D054685:Lymphoma, Primary Effusion / Q000150:complications / Q000175:diagnosis*; D008297:Male; D008875:Middle Aged; D013274:Stomach Neoplasms / Q000473:pathology