The effects of nutritional supplementation throughout an endurance run on leucine kinetics during recovery.
This study determined the effect of nutritional supplementation throughout endurance exercise on whole-body leucine kinetics (leucine rate of appearance [Ra], oxidation [Ox], and nonoxidative leucine disposal [NOLD]) during recovery. Five trained men underwent a 2-h run at 65% VO(2max), during which a carbohydrate (CHO), mixed protein-carbohydrate (milk), or placebo (PLA) drink was consumed. Leucine kinetics were assessed during recovery using a primed, continuous infusion of 1-13C leucine. Leucine Ra and NOLD were lower for milk than for PLA. Ox was higher after milk-supplemented exercise than after CHO or PLA. Although consuming milk during the run affected whole-body leucine kinetics, the benefits of such a practice for athletes remain unclear. Additional studies are needed to determine whether protein supplementation during exercise can optimize protein utilization during recovery.
Department of Nutritional Sciences, University of Connecticut, Storrs, CT 06269, USA.
Sharon L
SL
Miller
P Courtney
PC
Gaine
Carl M
CM
Maresh
Lawrence E
LE
Armstrong
Cara B
CB
Ebbeling
Linda S
LS
Lamont
Nancy R
NR
Rodriguez
D000293:Adolescent; D000328:Adult; D000818:Animals; D002247:Carbon Isotopes; D018592:Cross-Over Studies; D004040:Dietary Carbohydrates / Q000378:metabolism / Q000494:pharmacology*; D004044:Dietary Proteins / Q000378:metabolism / Q000494:pharmacology*; D019587:Dietary Supplements; D004734:Energy Metabolism; D006801:Humans; D007930:Leucine / Q000493:pharmacokinetics*; D008297:Male; D008892:Milk; D010101:Oxygen Consumption; D010807:Physical Endurance / Q000502:physiology*
D002247:Carbon Isotopes; D004040:Dietary Carbohydrates; D004044:Dietary Proteins; D007930:Leucine