The risky business of ageing.
This commentary reflects on the work by Chen and colleagues which compares the effect of an immune challenge in hippocampus and hippocampal-dependent function young and aged mice.
Lynch
Marina A
MA
Trinity College Institute of Neuroscience, Trinity College, Dublin, Ireland. lynchma@tcd.ie
D000375:Aging / Q000378:metabolism*; D000818:Animals; D016207:Cytokines / Q000378:metabolism; D006624:Hippocampus / Q000187:drug effects* / Q000378:metabolism*; D007107:Immune System / Q000187:drug effects*; D018836:Inflammation Mediators / Q000378:metabolism*; D053583:Interleukin-1beta / Q000235:genetics / Q000378:metabolism; D008070:Lipopolysaccharides / Q000494:pharmacology*; D051379:Mice; D012333:RNA, Messenger / Q000378:metabolism
D016207:Cytokines; D018836:Inflammation Mediators; D053583:Interleukin-1beta; D008070:Lipopolysaccharides; D012333:RNA, Messenger