Isolated thrombocytopenia in children: thinking beyond idiopathic thrombocytopenic purpura and leukaemia.
The commonest cause of isolated thrombocytopenia in an otherwise well child is idiopathic thrombocytopenic purpura (ITP). The inherited thrombocytopenias such as Bernard-Soulier syndrome are rare but often misdiagnosed as ITP owing to a similar clinical presentation. We describe a child with Bernard-Soulier syndrome who presented with isolated thrombocytopenia, mimicking ITP. Features which help to differentiate these two conditions are discussed with a brief literature review.
Kottayam
Radhakrishnan
R
Centre for Children's Cancer and Blood Disorders, Sydney Children's Hospital, Randwick, New South Wales, Australia.
Rozenberg
Gillian
G
Brighton
Tim
T
Cohn
Richard J
RJ
D001606:Bernard-Soulier Syndrome / Q000503:physiopathology*; D002675:Child, Preschool; D003937:Diagnosis, Differential; D006801:Humans; D007938:Leukemia / Q000175:diagnosis*; D008297:Male; D009517:New South Wales; D013921:Thrombocytopenia / Q000175:diagnosis* / Q000209:etiology