Does red-man reaction stimulate macrophage activation syndrome in children with systemic juvenile idiopathic arthritis?
Macrophage activation syndrome (MAS) is a major cause of death in patients with systemic juvenile idiopathic arthritis (JIA). We describe 4 patients who developed MAS during or after vancomycin treatment. Vancomycin should be used with great care in patients with systemic JIA.
Olgar
Seref
S
Pediatric Cardiology Unit, Istanbul University, Istanbul Faculty of Medicine, Istanbul, Turkey. solgar@hacettepe.edu.tr
Ertugrul
Turkan
T
Devecioglu
Omer
O
Nisli
Kemal
K
Omeroglu
Rukiye Eker
RE
D000293:Adolescent; D000900:Anti-Bacterial Agents / Q000009:adverse effects*; D001171:Arthritis, Juvenile / Q000188:drug therapy* / Q000276:immunology*; D002648:Child; D005260:Female; D006801:Humans; D008262:Macrophage Activation / Q000276:immunology*; D008264:Macrophages / Q000187:drug effects* / Q000276:immunology; D008297:Male; D013577:Syndrome; D016896:Treatment Outcome; D014640:Vancomycin / Q000009:adverse effects*
D000900:Anti-Bacterial Agents; D014640:Vancomycin