Effect of gold nanoparticles on spermatozoa: the first world report.
OBJECTIVE
To evaluate the spermatotoxicity of gold nanoparticles.


METHODS
Experimental study.


METHODS
A university in Thailand.


METHODS
Single-donor fresh semen sample.


METHODS
A mixture of gold nanoparticle solution and semen was prepared and further analyzed.


METHODS
Spermatozoa appearance.


RESULTS
After mixing the semen with a gold nanoparticle solution, 25% of sperm were not motile. Penetration of gold nanoparticle into the sperm heads and tails was observed.


CONCLUSIONS
Spermatotoxicity of the gold nanoparticle can be detected.
Wiwanitkit
Viroj
V
Department of Clinical Laboratory Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand. wviroj@yahoo.com
Sereemaspun
Amornpun
A
Rojanathanes
Rojrit
R
D006046:Gold / Q000633:toxicity*; D006801:Humans; D008297:Male; D053758:Nanoparticles; D012016:Reference Values; D012661:Semen / Q000187:drug effects / Q000502:physiology; D013094:Spermatozoa / Q000187:drug effects / Q000502:physiology*
D006046:Gold