[The electroretinogram of infants with nystagmus].
OBJECTIVE
To find the characteristics and clinical application of electroretinogram (ERG) in infants with nystagmus.


METHODS
Forty-six cases (92 eyes) of infants with nystagmus (aged 2-72 months old) were tested with Neuropack MEB-2200K system according to the ERG standard of ISCEV.


RESULTS
Five kinds of ERG responses of all subjects but one could be recorded. The abnormal rates of the rod ERG, standard mixture ERG, oscillatory potentials, single-flash cone ERG and 30 Hz flicker response were 65%, 86%, 61%, 77% and 62% respectively. The ERG abnormalities were evaluated from the 5 responses. The rod ERG decreased in 5 eyes. The rod-cone ERG decreased in 11 eyes. The cone ERG decreased in 14 eyes. The cone-rod ERG decreased in 23 eyes. The standard mixture ERG decreased in 8 eyes. The ERG was unrecordable in 8 eyes. The mild, middle, and severe decreases of rod and cone ERG appeared in 5 eyes respectively. The normal ERG was only recorded in 8 eyes.


CONCLUSIONS
Abnormal rate of ERG is 91% in infants with nystagmus. The retina abnormality may pay an important role in the pathogenesis of nystagmus.
State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510060, China.
Shizhou
S
Huang
Dezheng
D
Wu
Tianqin
T
Guan
Caijiao
C
Liu
Lezheng
L
Wu
D002675:Child, Preschool; D004596:Electroretinography; D006801:Humans; D007223:Infant; D009759:Nystagmus, Pathologic / Q000473:pathology* / Q000503:physiopathology*