Chromosomal rearrangements in lipofibromatosis.
Lipofibromatosis is a relatively rare pediatric neoplasm, which usually manifests as an ill-defined soft tissue mass involving the upper and lower distal extremities, the trunk, and, less frequently, the head. To date, no cytogenetic abnormalities have been reported in this uncommon neoplasm. We present a case of lipofibromatosis featuring a three-way t(4;9;6) translocation in a 5-year-old boy.
Department of Pathology, Yale University School of Medicine, 430 Congress Avenue, P.O. Box 208023, New Haven, CT 06520-8023, USA.
Barton
B
Kenney
Kathleen E
KE
Richkind
Gary
G
Friedlaender
Eduardo
E
Zambrano
D002675:Child, Preschool; D002869:Chromosome Aberrations; D002894:Chromosomes, Human, Pair 4; D002896:Chromosomes, Human, Pair 6; D002899:Chromosomes, Human, Pair 9; D006801:Humans; D007621:Karyotyping; D008067:Lipoma / Q000235:genetics* / Q000473:pathology; D008279:Magnetic Resonance Imaging; D008297:Male; D014178:Translocation, Genetic