Airway involvement in Wegener's granulomatosis.
Wegener's granulomatosis is characterized by necrotizing granulomatous inflammation and necrotizing vasculitis affecting predominantly small arteries, arterioles, capillaries, and venules. In contrast to the well-described pulmonary parenchymal involvement of Wegener's granulomatosis, the lower airway (tracheobronchial) disease manifestations are less well recognized by clinicians. Consequently, mild disease of the airways is easily missed. There is a relative paucity of published information on various tracheobronchial manifestations of Wegener's granulomatosis. This article provides a comprehensive review of the diagnosis and management of the infraglottic tracheobronchial disease manifestations.
Polychronopoulos
Vlassis S
VS
Third Pulmonary Department, Sismanaglion General Hospital, Athens, Greece.
Prakash
Udaya B S
UB
Golbin
Jason M
JM
Edell
Eric S
ES
Specks
Ulrich
U
D001982:Bronchial Diseases / Q000175:diagnosis* / Q000209:etiology / Q000628:therapy*; D001999:Bronchoscopy; D003937:Diagnosis, Differential; D005931:Glottis; D014890:Granulomatosis with Polyangiitis / Q000175:diagnosis* / Q000188:drug therapy / Q000503:physiopathology; D006801:Humans; D007818:Laryngeal Diseases / Q000175:diagnosis* / Q000209:etiology / Q000628:therapy*; D008279:Magnetic Resonance Imaging; D012129:Respiratory Function Tests; D014057:Tomography, X-Ray Computed