Modelling concepts and database implementation techniques for complex biological data.
Biological data such as protein structure and function, DNA sequences, and metabolic pathways require conceptual modelling characteristics that are not available in the widely used Entity-Relationship (ER) model and its variants, such as the Enhanced-Entity Relationship (EER) model. In particular, three constructs that occur frequently in bioinformatics data are ordered relationships, functional processes, and 3-dimensional (3D) structures. In this paper, we suggest a solution to this problem, requiring only minimal changes to the EER model by introducing specialised formal relationships for ordering, processes and molecular spatial structure. We show how these new concepts can be implemented in relational databases.
Department of Computer Science and Engineering, University of Texas at Arlington, Arlington, TX 76019, USA. elmasri@cse.uta.edu
Ramez
R
Elmasri
Feng
F
Ji
Jack
J
Fu
Yiming
Y
Zhang
D019295:Computational Biology; D003198:Computer Simulation; D003628:Database Management Systems; D016208:Databases, Factual; D030541:Databases, Genetic; D030562:Databases, Protein; D008967:Molecular Biology; D015398:Signal Transduction