[Analysis of blood coagulation factors in patients undergoing surgery due to endometrial cysts].
OBJECTIVE
The study was undertaken to evaluate selected blood coagulation factors in patients undergoing surgery, due to endometrial cysts and other ovarian benign cysts.


METHODS
Women involved in our study had not received any previous treatment for endometriosis and they had no history of any prior haemostatic disorders. Blood samples were collected before surgery and investigated for plasminogen, alpha2-antyplasmin, PAI-1 and tPA activity. As a control group, we have analyzed patients with benign gynecological diseases treated in our Department.


RESULTS
We have noticed higher mean concentration of plasminogen and alpha2-antyplasmin and lower mean concentration of PAI-1 and tPA activity in our patients in comparison with control group. Obtained results did not show any statistical significance.


CONCLUSIONS
Our analysis of haemostatic factors in blood samples did not show coagulation disorders in patients with endometriosis. Maybe there are only local coagulation disorders in endometrial tissue and its surrounding. In our opinion this problem requires further research and taking into consideration other factors.
Oddział Onkologii Ginekologicznej, Klinika Onkologii Uniwersytetu Medycznego w Poznaniu.
Jacek
J
Grabowski
Janina
J
Markowska
Kornelia
K
Tomaszewska
Natalia
N
Fischer
Jolanta
J
Nalewaj
D001779:Blood Coagulation Factors / Q000032:analysis*; D016022:Case-Control Studies; D003560:Cysts / Q000097:blood; D004715:Endometriosis / Q000097:blood*; D005260:Female; D006801:Humans; D010048:Ovarian Cysts / Q000097:blood*; D010958:Plasminogen / Q000032:analysis; D017395:Plasminogen Activator Inhibitor 1 / Q000097:blood; D012189:Retrospective Studies; D010959:Tissue Plasminogen Activator / Q000097:blood; D014591:Uterine Diseases / Q000097:blood; D000979:alpha-2-Antiplasmin / Q000032:analysis
D001779:Blood Coagulation Factors; D017395:Plasminogen Activator Inhibitor 1; D000979:alpha-2-Antiplasmin; D010958:Plasminogen; D010959:Tissue Plasminogen Activator