Bioactivity of two major constituents isolated from the essential oil of Artemisia judaica L.
The essential oil of Artemisia judaica L., grown on Sinai Peninsula of Egypt, was extracted via hydrodistillation. Chromatographic separation on repeated silica gel columns led to isolate two compounds namely piperitone and trans-ethyl cinnamate. Insecticidal, antifeedant and antifungal properties of the isolated compounds were examined. Both compounds showed pronounced insecticidal and antifeedant activity against the third instar larvae of Spodoptera littoralis (Boisd). trans-Ethyl cinnamate (LD(50)=0.37 microg/larva) was more toxic than piperitone (LD(50)=0.68microg/larva). The two isolated compounds revealed antifeedant activity in a concentration dependent manner, with complete feeding inhibition at a concentration of 1,000microg/ml. When tested for antifungal activity against four plant pathogenic fungi, the isolated compounds exhibited a moderate to high activity.
Department of Pesticide Chemistry, Faculty of Agriculture, 21545-El-Shatby, Alexandria University, Alexandria, Egypt. samir1969us@yahoo.com
Samir A M
SA
Abdelgaleil
Moustafa A
MA
Abbassy
Abdel-Salam H
AS
Belal
Mona A A
MA
Abdel Rasoul
D000818:Animals; D000935:Antifungal Agents / Q000302:isolation & purification / Q000494:pharmacology; D019306:Artemisia / Q000737:chemistry*; D002845:Chromatography; D004534:Egypt; D005658:Fungi / Q000187:drug effects / Q000254:growth & development; D007306:Insecticides / Q000302:isolation & purification / Q000633:toxicity; D007814:Larva / Q000187:drug effects; D009822:Oils, Volatile / Q000737:chemistry* / Q000302:isolation & purification / Q000633:toxicity; D010936:Plant Extracts / Q000737:chemistry / Q000302:isolation & purification / Q000633:toxicity; D058428:Silica Gel; D012822:Silicon Dioxide; D018411:Spodoptera / Q000187:drug effects* / Q000254:growth & development
D000935:Antifungal Agents; D007306:Insecticides; D009822:Oils, Volatile; D010936:Plant Extracts; D058428:Silica Gel; D012822:Silicon Dioxide