[Leptin, leptin gene, leptin gene receptor polymorphisms and pregnancy].
The article presents information about leptin as the major metabolic hormone. The structure, localization of the hormone and its receptor have been described focusing on maturation and fertility processes. Several polymorphisms of leptin gene and its receptor have been described as potential developmental factors of pregnancy complications such as diabetes mellitus or pregnancy induced hypertension.
Klinika Połoznictwa i Chorób Kobiecych Uniwersytetu Medycznego w Poznaniu. kpichk@gpsk.am.poznan.pl
Rafał
R
Iciek
Ewa
E
Wender-Ozegowska
Agnieszka
A
Seremak-Mrozikiewicz
Krzysztof
K
Drews
Jacek
J
Brazert
D016640:Diabetes, Gestational / Q000235:genetics*; D005260:Female; D006801:Humans; D046110:Hypertension, Pregnancy-Induced / Q000235:genetics*; D020738:Leptin / Q000378:metabolism*; D011110:Polymorphism, Genetic; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000235:genetics*; D054411:Receptors, Leptin / Q000235:genetics*
C515448:LEPR protein, human; D020738:Leptin; D054411:Receptors, Leptin