Neuropsychiatric symptoms are associated with disability in cognitively impaired Latino elderly with and without dementia: results from the Sacramento Area Latino study on Aging.
OBJECTIVE
To examine the relationship between neuropsychiatric symptoms burden and disability in cognitively impaired older Latinos.


METHODS
Subjects in the cross-sectional study were 95 cognitively impaired (both demented and non-demented) non-institutionalized Latino elderly participating in an epidemiological cohort study and their family caregivers. Care recipient neuropsychiatric symptoms (Neuropsychiatric Inventory) and level of functional impairment (i.e. impairment in activities of daily living and instrumental activities of daily living) were assessed through interviews with family caregivers.


RESULTS
Both NPI total score and NPI depression subscale score were significantly associated with disability before and after controlling for potential confounding variables. The strength of the association between higher neuropsychiatric symptom levels and higher disability was similar for both the cognitively impaired not demented and demented groups.


CONCLUSIONS
Neuropsychiatric symptoms are associated with increased disability in a community sample of cognitively impaired Latino elderly. More effective identification and treatment of neuropsychiatric symptoms may improve functioning in older Latinos and reduce health disparities for this population.
Department of Psychiatry and Alzheimer's Disease Center, University of California, CA, USA. ladson.hinton@ucdmc.ucdavis.edu
Ladson
L
Hinton
Sarah
S
Tomaszewski Farias
Jacob
J
Wegelin
D000203:Activities of Daily Living; D000368:Aged; D000369:Aged, 80 and over; D003072:Cognition Disorders / Q000523:psychology* / Q000534:rehabilitation; D003430:Cross-Sectional Studies; D003704:Dementia / Q000523:psychology* / Q000534:rehabilitation; D003863:Depression / Q000523:psychology / Q000534:rehabilitation; D004185:Disability Evaluation; D006233:Persons with Disabilities / Q000523:psychology*; D005260:Female; D015577:Geriatric Assessment; D006801:Humans; D008297:Male; D001523:Mental Disorders / Q000523:psychology / Q000534:rehabilitation; D008875:Middle Aged; D009483:Neuropsychological Tests