A phenanthrene modified RNA hairpin.
The influence of hairpin loop replacement with the phenanthrene moiety in RNA was investigated. The stability of this novel structure was compared to a hairpin with a U(4) loop, an extra stable tetra-loop (UUCG), and an analogous phenanthrene modified DNA hairpin. Thermal denaturation experiments and CD spectra were used to study the structure and stability of the modified hairpin.
Department of Chemistry and Biochemistry, University of Bern, Bern, Switzerland.
Ivan
I
Trkulja
Alfred
A
Stutz
Robert
R
Häner
D002942:Circular Dichroism; D004247:DNA / Q000737:chemistry; D006358:Hot Temperature; D015394:Molecular Structure; D009690:Nucleic Acid Conformation; D010616:Phenanthrenes / Q000737:chemistry*; D012313:RNA / Q000138:chemical synthesis* / Q000737:chemistry*; D020871:RNA Stability
D010616:Phenanthrenes; C031181:phenanthrene; D012313:RNA; D004247:DNA