title: A rare case of classic testicular seminoma in an 86-year-old shows similar proliferation rate as in younger men.
abstract: We present a rare case of classic seminoma in an 86-year-old man. Combined mitotic count, the presence or absence of intravascular invasion, and the expression of PCNA, Ki67, and p53 were compared between this octogenarian and the tumors of four randomly selected standard younger men. These histologic features were chosen to compare the potential biologic activity of these tumors. The phenotype of classic seminomas in octogenarians seems to be the same as in younger men, and treatment paradigms should remain unchanged.
authors: Department of Surgery, Division of Urology, University of Western Ontario, London Health Sciences Centre-Victoria Hospital, London, Ontario, Canada.
authors: Kirsten
authors: K
authors: Foell
authors: Mildred
authors: M
authors: Martens
authors: Jonathan I
authors: JI
authors: Izawa
mesh_terms: D000328:Adult; D000367:Age Factors; D000369:Aged, 80 and over; D049109:Cell Proliferation; D006801:Humans; D008297:Male; D008875:Middle Aged; D018239:Seminoma / Q000473:pathology*; D013736:Testicular Neoplasms / Q000473:pathology*