title: Strategies for the use of mixture-based synthetic combinatorial libraries: scaffold ranking, direct testing in vivo, and enhanced deconvolution by computational methods.
authors: Torrey Pines Institute for Molecular Studies, 3550 General Atomics Court, San Diego, California 92121, USA. rhoughten@tpims.org
authors: Richard A
authors: RA
authors: Houghten
authors: Clemencia
authors: C
authors: Pinilla
authors: Marc A
authors: MA
authors: Giulianotti
authors: Jon R
authors: JR
authors: Appel
authors: Colette T
authors: CT
authors: Dooley
authors: Adel
authors: A
authors: Nefzi
authors: John M
authors: JM
authors: Ostresh
authors: Yongping
authors: Y
authors: Yu
authors: Gerald M
authors: GM
authors: Maggiora
authors: Jose L
authors: JL
authors: Medina-Franco
authors: Daniela
authors: D
authors: Brunner
authors: Jeff
authors: J
authors: Schneider
mesh_terms: D000818:Animals; D020650:Combinatorial Chemistry Techniques / Q000379:methods / Q000706:statistics & numerical data; D045424:Complex Mixtures / Q000737:chemistry*; D015195:Drug Design; D004353:Drug Evaluation, Preclinical / Q000379:methods / Q000706:statistics & numerical data; D006801:Humans; D004364:Pharmaceutical Preparations / Q000737:chemistry*; D054852:Small Molecule Libraries / Q000737:chemistry*
chemical_list: D045424:Complex Mixtures; D004364:Pharmaceutical Preparations; D054852:Small Molecule Libraries