Possible roles of the weakly inward rectifying k+ channel Kir4.1 (KCNJ10) in the pre-Bötzinger complex.
Rhythmic activity of respiratory neurons is dependent on the clearance of neurotransmitter by astrocytes. Astrocytes should also be involved in the permanent and rapid clearance of extracellular ions. We analyzed the expression of the weakly inwardly rectifying K+ channel Kir4.1 (KCNJ10) in the respiratory network and studied the possible functions for neuronal activity in the pre-Bötzinger complex.
Papadopoulos
Nestoras
N
Department of Neuro- and Sensory Physiology, Georg-August-University Göttingen, 37073 Göttingen, Germany.
Winter
Stefan M
SM
Härtel
Kai
K
Kaiser
Melanie
M
Neusch
Clemens
C
Hülsmann
Swen
S
D000818:Animals; D001253:Astrocytes / Q000502:physiology*; D017353:Gene Deletion; D005904:Glial Fibrillary Acidic Protein / Q000235:genetics; D006801:Humans; D051379:Mice; D018345:Mice, Knockout; D008822:Mice, Transgenic; D024661:Potassium Channels, Inwardly Rectifying / Q000172:deficiency / Q000235:genetics / Q000502:physiology*; D012143:Respiratory Physiological Phenomena; D009435:Synaptic Transmission / Q000502:physiology; D000098854:Kcnj10 Channel
D005904:Glial Fibrillary Acidic Protein; D000098854:Kcnj10 Channel; D024661:Potassium Channels, Inwardly Rectifying