title: Determination of serum zinc-alpha-2-glycoprotein in patients with metabolic syndrome by a new ELISA.
abstract: OBJECTIVE
  To develop an assay for the determination of ZAG in human serum, and to investigate its clinical relevance as a marker of metabolic syndrome.
  
  
  METHODS
  A new sandwich ELISA was introduced and clinically tested.
  
  
  RESULTS
  ZAG serum level did not differentiate healthy subjects (27.4+/-8.3 mg/L; N=132) from patients with metabolic syndrome (24.9+/-8.1; N=92). ZAG correlated with glucose, creatinine and uric acid.
  
  
  CONCLUSIONS
  The immunoassay offers a new research tool for glucose metabolism.
authors: Department of Laboratory Medicine and Department of Medicine, Sternberk Hospital, Jivavská 20, Sternberk, Czech Republic. david.stejskal@nemstbk.cz
authors: D
authors: D
authors: Stejskal
authors: M
authors: M
authors: Karpísek
authors: H
authors: H
authors: Reutová
authors: P
authors: P
authors: Stejskal
authors: H
authors: H
authors: Kotolová
authors: Peter
authors: P
authors: Kollár
mesh_terms: D000368:Aged; D001786:Blood Glucose / Q000378:metabolism; D003404:Creatinine / Q000097:blood; D004797:Enzyme-Linked Immunosorbent Assay / Q000379:methods; D005260:Female; D006801:Humans; D008297:Male; D024821:Metabolic Syndrome / Q000097:blood*; D008875:Middle Aged; D029589:Seminal Plasma Proteins / Q000097:blood*; D014527:Uric Acid / Q000097:blood; D000090203:Zn-Alpha-2-Glycoprotein
chemical_list: D001786:Blood Glucose; D029589:Seminal Plasma Proteins; D000090203:Zn-Alpha-2-Glycoprotein; D014527:Uric Acid; D003404:Creatinine