[A case of therapy-related acute myeloid leukemia associated with inv(16)].
The inv(16)(p13q22) is found in de novo AML and is closely associated with the FAB subtype M4eo. The inv(16) is rarely reported in therapy-related AML (t-AML) patients. Herein, we report a case of t-AML with inv(16) after combination chemotherapy using antimitotic agent and alkylating agent (cis-platin-paclitaxel) for ovarian serous cystadenocarcinoma.
Lee
So-Young
SY
Department of Laboratory Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Kim
Myungshin
M
Lim
Jihyang
J
Kim
Yonggoo
Y
Han
Kyungja
K
Kim
Sung Yong
SY
Kim
Hee Je
HJ
Park
In-Yang
IY
D050256:Antimitotic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects* / Q000627:therapeutic use; D007446:Chromosome Inversion; D002885:Chromosomes, Human, Pair 16 / Q000235:genetics*; D002945:Cisplatin / Q000009:adverse effects / Q000627:therapeutic use; D005260:Female; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000139:chemically induced* / Q000473:pathology; D008875:Middle Aged; D017239:Paclitaxel; D043823:Taxoids / Q000009:adverse effects / Q000627:therapeutic use
D050256:Antimitotic Agents; D043823:Taxoids; D017239:Paclitaxel; D002945:Cisplatin