Synthesis of functionalised aromatic oligamide rods.
A current goal in synthetic chemistry is the design and synthesis of molecules that adopt well defined conformations-so called foldamers. In this manuscript we describe a modular approach for construction of rod shaped para-oligobenzamide molecules. Our approach permits regiospecific incorporation of side chains through a phenolic ether linkage on the scaffold; a feature that partly restricts the conformation of the rod through intramolecular hydrogen-bonding.
Plante
Jeffrey
J
School of Chemistry, University of Leeds, Woodhouse Lane, Leeds, LS29JT, United Kingdom. A.J.Wilson@leeds.ac.uk.
Campbell
Fred
F
Malkova
Barbora
B
Kilner
Colin
C
Warriner
Stuart L
SL
Wilson
Andrew J
AJ
D001549:Benzamides / Q000138:chemical synthesis* / Q000737:chemistry*; D018360:Crystallography, X-Ray; D004986:Ether / Q000737:chemistry; D006860:Hydrogen Bonding; D008958:Models, Molecular; D008968:Molecular Conformation; D009010:Monte Carlo Method
D001549:Benzamides; D004986:Ether