title: Nonablative 1,064-nm Nd:YAG laser for treating atrophic facial acne scars: histologic and clinical analysis.
abstract: BACKGROUND
  Non-ablative methods have been attempted in treating atrophic facial scars, but the histologic findings do not always coincide with the clinical results and patient satisfaction.
  
  
  OBJECTIVE
  To study the effects and safety of the Nd:YAG laser for treating atrophic facial scars.
  
  
  METHODS
  Twelve subjects (skin phototypes II-V) with mild to moderate atrophic facial acne scars received five monthly treatments with 1,064 nm Nd:YAG laser and were photographed before, in the middle of, and 6 months after the last treatment. Histologic evaluations were performed on skin biopsies obtained before treatment and 1 month after the last session. Collagen quantification per area, before and after the treatment, was performed by morphometry, with computerized image analysis. Patient satisfaction and clinical condition were assessed using standard grading scales.
  
  
  RESULTS
  Mild to moderate clinical improvement was observed in most patients. Photographic assessment of scars found visible cosmetic improvement in eleven patients. All patients were satisfied. There were statistically significant collagen increases in the dermis following the treatment. Side effects were limited to mild transient erythema and increased skin sensitivity after the procedure.
  
  
  CONCLUSIONS
  The 1,064 nm Nd:YAG laser is a safe and effective nonablative method for improving atrophic scars, even in darker skin.
authors: Department of Dermatology, University of São Paulo, São Paulo, Brazil. raquelkl@uol.com.br
authors: Raquel
authors: R
authors: Keller
authors: Walter
authors: W
authors: Belda Júnior
authors: Neusa Yuriko Sakai
authors: NY
authors: Valente
authors: Consuelo Junqueira
authors: CJ
authors: Rodrigues
mesh_terms: D000152:Acne Vulgaris / Q000150:complications*; D000293:Adolescent; D000328:Adult; D001284:Atrophy; D001706:Biopsy; D002921:Cicatrix / Q000209:etiology / Q000601:surgery*; D062109:Dermatologic Surgical Procedures; D005145:Face; D006801:Humans; D053685:Laser Therapy; D053844:Lasers, Solid-State / Q000627:therapeutic use; D012867:Skin / Q000473:pathology