title: Alternative and expedient asymmetric syntheses of L-(+)-noviose.
abstract: L-(+)-noviose, the sugar component of the antibiotic novobiocin, was synthesized from readily available non-carbohydrate starting materials relying on stoichiometric and asymmetric processes by two independent methods, comprising six and nine steps, in 27 and 20% overall yields, respectively.
authors: Department of Chemistry, Université de Montréal, PO Box 6128, Station Centre-ville, Montréal, QC, H3C 3J7 Canada.
authors: Stephen
authors: S
authors: Hanessian
authors: Luciana
authors: L
authors: Auzzas
mesh_terms: D002384:Catalysis; D015394:Molecular Structure; D009005:Monosaccharides / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism; D013302:Streptomyces / Q000737:chemistry
chemical_list: D009005:Monosaccharides; C494073:noviose