title: Performance of commercial latex agglutination tests for the differentiation of Candida dubliniensis and Candida albicans in routine diagnostics.
abstract: Candida dubliniensis is phenotypically similar to Candida albicans and may therefore be underdiagnosed in the clinical microbiology laboratory. The performance of Bichro-Dubli latex agglutination test for rapid species identification of C. dubliniensis was prospectively evaluated on 111 vaginal and 118 respiratory isolates. These had presumptively been identified as C. albicans/C. dubliniensis by their green colonies on CHROMagar Candida plates. Bichro-Dubli test identifed 2 (1.8%) vaginal and 6 (5.1%) respiratory isolates as C. dubliniensis. The test was also positive for 37 C. dubliniensis control strains characterised by 18S-28S DNA-sequencing. Bichro-Dubli test is thus a sensitive and accurate tool for rapid diagnostics in routine laboratories.
authors: Department of Clinical Microbiology, Karolinska University Laboratory, Solna, Sweden. erja.chryssanthou@karolinska.se
authors: E
authors: E
authors: Chryssanthou
authors: V
authors: V
authors: Fernandez
authors: B
authors: B
authors: Petrini
mesh_terms: D001992:Bronchoalveolar Lavage Fluid / Q000382:microbiology; D002175:Candida / Q000145:classification* / Q000254:growth & development / Q000302:isolation & purification; D002176:Candida albicans / Q000145:classification* / Q000254:growth & development / Q000302:isolation & purification; D003955:Diagnostic Tests, Routine; D005260:Female; D006801:Humans; D007841:Latex Fixation Tests / Q000379:methods*; D013183:Sputum / Q000382:microbiology; D014621:Vagina / Q000382:microbiology