A facile synthesis of 2-methylquinolines via Pd-catalyzed aza-wacker oxidative cyclization.
A novel Pd-catalyzed Wacker-type oxidative cyclization under air is described. By using this cyclization, a series of 2-methylquinolines are readily prepared with good yields under mild conditions.
Zhang
Zuhui
Z
Hefei National Laboratory for Physical Science at Microscale, Joint Laboratory of Green Synthetic Chemistry and Department of Chemistry, University of Science and Technology of China, Hefei, Anhui, 230026, People's Republic of China.
Tan
Jiajing
J
Wang
Zhiyong
Z
D020650:Combinatorial Chemistry Techniques; D003500:Cyclization; D015394:Molecular Structure; D010084:Oxidation-Reduction; D010165:Palladium / Q000737:chemistry*; D011804:Quinolines / Q000138:chemical synthesis* / Q000737:chemistry
D011804:Quinolines; D010165:Palladium