[The epidemic of chronic kidney disease requires the estimation of glomerular filtration rate].
Nowadays chronic kidney disease has become a major public health problem due to the great increase in atherogenic nephropathies. In the absence of classic renal symptoms, chronic kidney disease is mostly diagnosed when renal failure is already advanced, although it can be revealed by laboratory tests in the earlier stages. When diagnosis is late, the progression to end-stage renal failure is unavoidable and renal replacement therapy is needed. Even early-moderate renal failure significantly increases the risks for atherosclerosis, thereby leading to the deaths of patients from cardiovascular disease before initiation of dialysis. Therefore screening for asymptomatic chronic kidney disease is urgently needed. Estimated glomerular filtration rate has the greatest importance in the screening and in the timely intervention to slow down the progression of renal failure and cardiovascular disease. In 2005, the Hungarian Society of Nephrologists and the Hungarian Society of Laboratory Medicine suggested the automatic estimation and reporting of glomerular filtration rate, each time serum creatinine measurements were made. This practice is used more frequently by laboratories in Hungary. This article aims to help facilitate the utilization and evaluation of estimated glomerular filtration rate.
Mátyus
János
J
Debreceni Egyetem OEC Belgyógyászati Intézet I. Belklinika, Nefrológiai Tanszék Debrecen Pf. 19. 4012. matyus@internal.med.unideb.hu
V Oláh
Anna
A
Ujhelyi
László
L
Kárpáti
István
I
Balla
József
J
D050197:Atherosclerosis / Q000209:etiology / Q000517:prevention & control; D002908:Chronic Disease; D003404:Creatinine / Q000097:blood; D005919:Glomerular Filtration Rate; D006801:Humans; D006814:Hungary / Q000453:epidemiology; D007674:Kidney Diseases / Q000150:complications / Q000175:diagnosis / Q000453:epidemiology* / Q000503:physiopathology* / Q000517:prevention & control; D008403:Mass Screening / Q000379:methods*; D011237:Predictive Value of Tests; D012955:Societies, Medical
D003404:Creatinine