The engineering analysis of bioheat equation and penile hemodynamic relationships in the diagnosis of erectile dysfunction: part I-theoretical study and mathematical modeling.
The extent to which skin surface bioheat perfusion predicts penile physiological response such as an erection has not been extensively investigated. A biomechanical engineering study was performed to compare bioheat distribution on penile skin surface resulting from an induced erection at steady state to examine the efficacy of such method as an adjunct tool for the diagnosis and classification of erectile dysfunction (ED) due to different etiology. We based our arguments on the principle that blood vessel activity and perfusion to corpus cavernosa at the erect state are almost always higher than that in the flaccid state. Our results showed that a difference of 0.1-0.3 degrees C can be observed and hence used to develop database of 'smart diagnosis' for ED using the machine artificial intelligence. It is anticipated that such basic research into blood flow is critical, as blood perfusion into corpus cavernosa is the most influential factor determining functional erectile quality contributing to successful coitus. Increased understanding of the hemodynamic response profile contributes toward optimal treatment and thus enables clinicians to adopt an appropriate management scheme for ED.
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W K
WK
School of Mechanical and Aerospace Engineering, Nanyang Technological University, Singapore, Singapore.
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E Y K
EY
Chia
S J
SJ
D000704:Analysis of Variance; D001696:Biomechanical Phenomena; D001831:Body Temperature; D007172:Erectile Dysfunction / Q000175:diagnosis / Q000503:physiopathology*; D006439:Hemodynamics; D006358:Hot Temperature; D006801:Humans; D008297:Male; D008962:Models, Theoretical; D010410:Penile Erection / Q000502:physiology*; D010413:Penis / Q000098:blood supply* / Q000502:physiology; D012039:Regional Blood Flow