title: A rare case of extraventricular neurocytoma.
abstract: We report an unusual case of extraventricular (cerebral) neurocytoma with a long, 25-year history, and which appeared to transform to neuroblastoma. In 1978, an 18-year-old woman was treated for right frontal oligodendroglioma. Eighteen years later (in 1996), recurrence of tumor in the fourth ventricle was noted and was treated with gamma-knife radiotherapy. The tumor shrunk transiently, but 7 years later (in 2004), MRI study demonstrated a second recurrence and ventricular dissemination. Partial removal was performed, and histological examination revealed that tumor cells had round or oval nuclei with halos. Frequent mitoses and vascular proliferation were observed. The MIB-1 LI was 80%. Despite postoperative whole-brain radiotherapy to a total dose of 30 Gy, the tumor progressed, and she died at 4 months after the second surgery.
authors: Department of Neurosurgery, Yamagata University, School of Medicine, 2-2-2 Iidanishi, Yamagata, 990-9585, Japan. nouge@idw03.id.yamagata-u.ac.jp
authors: Kaori
authors: K
authors: Sakurada
authors: Masahiro
authors: M
authors: Akasaka
authors: Hideo
authors: H
authors: Kuchiki
authors: Makoto
authors: M
authors: Saino
authors: Wataru
authors: W
authors: Mori
authors: Shinya
authors: S
authors: Sato
authors: Yoichi
authors: Y
authors: Nakazato
authors: Takamasa
authors: T
authors: Kayama
mesh_terms: D000293:Adolescent; D000328:Adult; D001932:Brain Neoplasms / Q000473:pathology*; D003951:Diagnostic Errors; D005260:Female; D020546:Fourth Ventricle / Q000473:pathology; D005625:Frontal Lobe / Q000473:pathology; D006801:Humans; D009364:Neoplasm Recurrence, Local / Q000473:pathology* / Q000628:therapy; D009447:Neuroblastoma / Q000473:pathology*; D018306:Neurocytoma / Q000473:pathology* / Q000628:therapy; D009837:Oligodendroglioma / Q000473:pathology*