Inhibition of heme protein redox cycling: reduction of ferryl heme by iron chelators and the role of a novel through-protein electron transfer pathway.
Roberts
L Jackson
LJ
Department of Pharmacology, Vanderbilt University, Nashville, TN 37232, USA. jack.roberts@vanderbilt.edu
D000818:Animals; D004579:Electron Transport; D006418:Heme / Q000378:metabolism*; D006801:Humans; D007502:Iron Chelating Agents / Q000494:pharmacology*; D008786:Metmyoglobin / Q000187:drug effects* / Q000378:metabolism; D010084:Oxidation-Reduction / Q000187:drug effects
D007502:Iron Chelating Agents; C028048:ferrylmyoglobin; D008786:Metmyoglobin; D006418:Heme