Enhancer organization: transistor with a twist or something in a different vein?
A specific group of enhancers that act in the early Drosophila embryo have a highly conserved arrangement of transcription factor binding sites. Computational modeling of these enhancers suggests interesting parallels with electronic transistors and optical image processors.
Zartman
Jeremiah J
JJ
Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, New Jersey 08544, USA.
Shvartsman
Stanislav Y
SY
D000818:Animals; D001665:Binding Sites; D004330:Drosophila; D004742:Enhancer Elements, Genetic; D018507:Gene Expression Regulation, Developmental; D007091:Image Processing, Computer-Assisted; D008954:Models, Biological; D014157:Transcription Factors / Q000378:metabolism*; D014173:Transistors, Electronic
D014157:Transcription Factors