Oxybutynin-associated esotropia.
A 5-year-old girl with previously unrecognized hyperopia of approximately +3.00 D developed esotropia while being treated with oxybutynin for enuresis. The esotropia disappeared with cessation of oxybutynin and correction of her hyperopia. When the hyperopic correction was removed, she had a small esophoria. The esotropia was presumably triggered by the anticholinergic effect of oxybutynin, which reduced the ability to accommodate. The increased accommodative effort for vision generated an esotropia as a result of the accommodative convergence/accommodation ratio.
Wong
Elaine Y H
EY
Ocular-Motility Clinic, The Royal Victorian Eye and Ear Hospital, Melbourne, Australia. e.wong@unimelb.edu.au
Harding
Anton
A
Kowal
Lionel
L
D000065:Accommodation, Ocular / Q000187:drug effects; D002675:Child, Preschool; D003290:Convergence, Ocular / Q000187:drug effects; D004775:Enuresis / Q000188:drug therapy; D004948:Esotropia / Q000139:chemically induced*; D005260:Female; D006801:Humans; D008333:Mandelic Acids / Q000009:adverse effects*; D018727:Muscarinic Antagonists / Q000009:adverse effects*
D008333:Mandelic Acids; D018727:Muscarinic Antagonists; C005419:oxybutynin