title: Long-term survival in patients older than 80 years hospitalised for heart failure. A 5-year prospective study.
abstract: BACKGROUND
  Although heart failure (HF) is frequent in elderly patients, few studies have focused on patients older than 80 years.
  
  
  OBJECTIVE
  To evaluate the clinical features, treatment and long-term prognosis of HF in patients older than 80 years.
  
  
  RESULTS
  Consecutive patients hospitalised for a first HF episode in the Somme Department (France) during 2000 were prospectively included. Of the 799 included patients, 305 (38%) were aged over 80 years. The elderly patients were mostly women with a high prevalence of atrial fibrillation, ischaemic and hypertensive heart disease. Ejection fraction (EF) was assessed in 68.5% of elderly patients and 61% had EF >or=50%. Angiotensin-converting enzyme inhibitors, beta-blockers, oral anticoagulants and statins were prescribed less frequently in elderly patients. The 5-year survival in elderly patients was 19%, dramatically lower than the survival of age- and sex-matched general population (48%). Cardiovascular causes were recorded in over 60% of deaths. On multivariable analysis, cancer, renal insufficiency, old myocardial infarction, diabetes, hyponatraemia and age were predictors of mortality in elderly patients. Reduced EF was a potent predictor of death (HR 1.72, 95%CI 1.24-2.37, p=0.001) in elderly patients.
  
  
  CONCLUSIONS
  Long-term prognosis in HF patients older than 80 years is poor, with a dramatic excess mortality compared to the elderly general population. Life-saving drugs are largely underused in elderly HF patients.
authors: INSERM, ERI 12, Amiens, France and University Hospital Amiens, France.
authors: Haïfa
authors: H
authors: Mahjoub
authors: Dan
authors: D
authors: Rusinaru
authors: Vicky
authors: V
authors: Soulière
authors: Chloé
authors: C
authors: Durier
authors: Marcel
authors: M
authors: Peltier
authors: Christophe
authors: C
authors: Tribouilloy
mesh_terms: D000369:Aged, 80 and over; D004812:Epidemiologic Methods; D005260:Female; D006333:Heart Failure / Q000188:drug therapy / Q000401:mortality*; D006760:Hospitalization; D006801:Humans; D008297:Male; D017741:Survivors