Menopause: developing a rational treatment plan.
In recent years, growing importance has been afforded to assisting women in coping with the menopausal transition. Menopause is a normal stage of development and a woman's attitude toward this transition embodies biological, psychological and social influences. An enlarging body of conflicting data concerning menopausal hormone therapy (MHT) demands reassessment of established paradigms of disease prevention and menopausal health. Currently, a woman's decision to participate in or abstain from menopausal HT is personal. It involves not only consideration of risk stratification of potential harm and benefit, but also involves her expectations and attitudes toward perceived physical and emotional changes associated with this change. Through the use of extensive patient history, quality-of-life questionnaires and powerful biological profiling, we may be able to develop a rational approach to menopausal HT that safely guides our patients through this transition.
Vitiello
Danielle
D
Division of Reproductive Endocrinology, Department of Obstetrics, Gynecology and Reproductive Sciences, Yale University School of Medicine, New Haven, Connecticut, USA.
Naftolin
Frederick
F
Naftoilin
Frederick
F
Taylor
Hugh S
HS
D001294:Attitude to Health; D015415:Biomarkers; D001943:Breast Neoplasms / Q000139:chemically induced; D002318:Cardiovascular Diseases / Q000517:prevention & control; D003657:Decision Making; D015914:Estrogen Replacement Therapy / Q000009:adverse effects; D005260:Female; D006487:Hemostasis / Q000187:drug effects; D006801:Humans; D008593:Menopause / Q000187:drug effects* / Q000502:physiology* / Q000523:psychology; D011788:Quality of Life; D016032:Randomized Controlled Trials as Topic; D012307:Risk Factors
D015415:Biomarkers