title: Self-reported gingivitis and tooth loss poorly predict C-reactive protein levels: a study among Finnish young adults.
abstract: OBJECTIVE
  Our aim in this cross-sectional study was to investigate whether self-reported gingivitis and tooth loss were associated with elevated levels of C-reactive protein (CRP) using the same study population where these dental conditions have earlier been associated with prevalent angina pectoris.
  
  
  METHODS
  The study population consisted of those Northern Finland birth cohort 1966 members who lived in Northern Finland or in the Helsinki region (n=8463) at the time of the survey (1996-1997). The participation rate in a health examination was 71% (n=6033). Gingivitis and tooth loss were determined on the basis of self-reported questions. Prevalence proportion ratios (PPR) and 95% confidence intervals (CI) were estimated using multivariate regression models.
  
  
  RESULTS
  The results showed that self-reported gingivitis and tooth loss were weakly associated with elevated levels of CRP (>3 mg/l): adjusted PPR 1.1, CI 1.0-1.3 and PPR 1.1, CI 0.7-1.7, respectively. The proportion of variation in CRP explained by self-reported gingivitis and tooth loss was small, being <1%.
  
  
  CONCLUSIONS
  The results suggest that self-reported gingivitis and tooth loss have a miniscule effect on CRP levels among a general population of young adults.
authors: Department of Periodontology and Geriatric Dentistry, Institute of Dentistry, University of Oulu, Oulu, Finland. pekka.ylostalo@oulu.fi
authors: Pekka V
authors: PV
authors: Ylöstalo
authors: Marjo-Riitta
authors: MR
authors: Järvelin
authors: Jaana
authors: J
authors: Laitinen
authors: Matti L E
authors: ML
authors: Knuuttila
mesh_terms: D000328:Adult; D000787:Angina Pectoris / Q000150:complications; D002097:C-Reactive Protein / Q000032:analysis*; D004812:Epidemiologic Methods; D005260:Female; D005387:Finland; D005891:Gingivitis / Q000097:blood* / Q000150:complications; D006801:Humans; D008297:Male; D016388:Tooth Loss / Q000097:blood* / Q000150:complications
chemical_list: D002097:C-Reactive Protein