QT prolongation and Torsades de Pointes following overdose of ziprasidone and amantadine.
Manini
Alex F
AF
New York City Poison Center, New York, NY, USA. manina01@med.nyu.edu
Raspberry
Dara
D
Hoffman
Robert S
RS
Nelson
Lewis S
LS
D000328:Adult; D000547:Amantadine / Q000009:adverse effects*; D018712:Analgesics, Non-Narcotic / Q000009:adverse effects*; D014150:Antipsychotic Agents / Q000009:adverse effects*; D062787:Drug Overdose; D004359:Drug Therapy, Combination; D004562:Electrocardiography; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007052:Ibuprofen / Q000009:adverse effects; D008133:Long QT Syndrome / Q000139:chemically induced* / Q000503:physiopathology; D010879:Piperazines / Q000009:adverse effects*; D013406:Suicide, Attempted; D013844:Thiazoles / Q000009:adverse effects*; D016171:Torsades de Pointes / Q000139:chemically induced* / Q000188:drug therapy / Q000503:physiopathology
D018712:Analgesics, Non-Narcotic; D014150:Antipsychotic Agents; D010879:Piperazines; D013844:Thiazoles; C092292:ziprasidone; D000547:Amantadine; D007052:Ibuprofen