title: Assessment of risk for substance use disorder consequent to consumption of illegal drugs: psychometric validation of the neurobehavior disinhibition trait.
abstract: Previous research has shown that the trait neurobehavior disinhibition (ND), which consists of affect, behavior, and cognitive indicators of self-regulation, is a significant predictor of substance use disorder (SUD) between childhood and young adulthood. The authors evaluated the psychometric properties of the ND trait in 278 boys evaluated at ages 10-12 and 16 years. ND score significantly predicted SUD and outcomes that commonly manifest in tandem with SUD by age 19, such as violence, arrests, committing crime while intoxicated, and concussion injury. In addition to predictive validity, the ND trait was found to have good construct, discriminative, and concurrent validity, as well as good test-retest and internal reliability. The ND trait may be useful for detecting youths at high risk for developing SUD and related outcomes.
authors: Center for Education and Drug Abuse Research (CEDAR), Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, PA 15261, USA. adacm@pit.edu
authors: Ada C
authors: AC
authors: Mezzich
authors: Ralph E
authors: RE
authors: Tarter
authors: Ulrike
authors: U
authors: Feske
authors: Levent
authors: L
authors: Kirisci
authors: Rebecca L
authors: RL
authors: McNamee
authors: Bang-Shiuh
authors: BS
authors: Day
mesh_terms: D000293:Adolescent; D001921:Brain / Q000503:physiopathology*; D002648:Child; D005260:Female; D006801:Humans; D013287:Illicit Drugs; D007266:Inhibition, Psychological; D008297:Male; D011594:Psychometrics; D015203:Reproducibility of Results; D018570:Risk Assessment; D012307:Risk Factors; D019966:Substance-Related Disorders / Q000453:epidemiology*; D013997:Time Factors
chemical_list: D013287:Illicit Drugs