title: Indirect traumatic optic neuropathy--retrospective interventional case series from a tertiary care center in eastern Nepal.
abstract: To report the demography, nature of insult and ocular characteristics in patients presenting with indirect traumatic optic neuropathy and to evaluate the visual outcome with mega dose methylprednisolone therapy. Retrospective hospital data analysis of all patients admitted with indirect traumatic optic neuropathy and treated with mega dose methylprednisolone therapy in the last three years was conducted. Nine patients (M:F= 8:1) were identified with unilateral optic nerve injury. Road traffic injury was the most common cause of injury. Lid ecchymosis and swelling on the same side was the most frequent ocular abnormality noted, followed by loss of consciousness. Time of presentation varied from 3 hours to 11 days. All patients except two had visual acuity of no light perception at presentation. Following therapy there was improvement in visual acuity in two patients who presented within two days of injury. Patients present late with traumatic optic neuropathy in this hospital. Most of the patients are with no light perception. High dose steroids was found to be beneficial only in patients presenting early (<two days).
authors: Department of Ophthalmology, B P Koirala Institute of Health Sciences, Dharan, Nepal.
authors: H
authors: H
authors: Das
authors: B P
authors: BP
authors: Badhu
authors: M A
authors: MA
authors: Gautam
mesh_terms: D000063:Accidents, Traffic; D000328:Adult; D002648:Child; D004438:Ecchymosis / Q000175:diagnosis / Q000209:etiology; D005260:Female; D006801:Humans; D008297:Male; D008775:Methylprednisolone / Q000008:administration & dosage*; D008875:Middle Aged; D009390:Nepal; D018696:Neuroprotective Agents / Q000008:administration & dosage*; D020221:Optic Nerve Injuries / Q000150:complications / Q000188:drug therapy* / Q000209:etiology*; D012189:Retrospective Studies; D016896:Treatment Outcome; D014474:Unconsciousness / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology; D015354:Vision, Low / Q000209:etiology; D014792:Visual Acuity
chemical_list: D018696:Neuroprotective Agents; D008775:Methylprednisolone