[Neuropathy, monoclonal gammopathy and autoantibodies: how to establish a link?].
Monoclonal gammopathies are frequently observed in subjects older than 50 years. Understanding the pathogenetic role of paraproteins in peripheral nervous system damage is a necessary step to establish a link between the monoclonal gammopathy and neuropathy. The clinical, electrophysiological, biological and histopathological features of these neuropathies related to paraproteins are important to ensure appropriate treatments.
Stojkovic
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G-H Pitié-Salpêtrière, Centre de référence des maladies neuromusculaires, Service du Pr J.-Y. Delattre, 47-84, boulevard de l'Hôpital, 75651 Paris cedex 13, France. tanya.stojkovic@psl-ap-hp-paris.fr
D017772:Amyloid Neuropathies / Q000276:immunology / Q000473:pathology / Q000503:physiopathology; D001323:Autoantibodies / Q000276:immunology / Q000502:physiology*; D020274:Autoimmune Diseases of the Nervous System / Q000276:immunology / Q000473:pathology* / Q000503:physiopathology; D006801:Humans; D007136:Immunoglobulins / Q000276:immunology; D016878:POEMS Syndrome / Q000276:immunology / Q000473:pathology / Q000503:physiopathology; D010265:Paraproteinemias / Q000276:immunology / Q000473:pathology* / Q000503:physiopathology
D001323:Autoantibodies; D007136:Immunoglobulins