title: Enantioselective C--C bond formation to sulfonylimines through use of the 2-pyridinesulfonyl group as a novel stereocontroller.
abstract: Enantioselective C--C bond formation to 2-pyridinesulfonylimines afforded products with good enantioselectivity. Dynamic induction of chirality on the sulfur by coordination of a chiral Lewis acid to the pyridine nitrogen and one of the prochiral sulfonyl oxygens induces enantioselectivity. Since the 2-pyridinesulfonyl group can easily be removed after the reaction, it acts not only as an activating group but also as an efficient stereocontroller.
authors: Department of Applied Chemistry, Graduate School of Engineering, Nagoya Institute of Technology, Gokiso, Showa-ku, Nagoya 466-8555, Japan. snakamur@nitech.ac.jp
authors: Shuichi
authors: S
authors: Nakamura
authors: Hiroki
authors: H
authors: Nakashima
authors: Hideki
authors: H
authors: Sugimoto
authors: Hideaki
authors: H
authors: Sano
authors: Masataka
authors: M
authors: Hattori
authors: Norio
authors: N
authors: Shibata
authors: Takeshi
authors: T
authors: Toru
mesh_terms: D002244:Carbon / Q000737:chemistry*; D007097:Imines / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D011725:Pyridines / Q000737:chemistry*; D013237:Stereoisomerism; D013450:Sulfones / Q000138:chemical synthesis* / Q000737:chemistry*
chemical_list: D007097:Imines; D011725:Pyridines; D013450:Sulfones; D002244:Carbon