Successful management of a Jehovah's Witness with thrombotic thrombocytopenic purpura unwilling to be treated with therapeutic plasma exchange.
Thrombotic thrombocytopenic purpura (TTP) is a life-threatening disease treated successfully with plasma exchange. Jehovah's Witnesses whose religious beliefs preclude them from accepting plasma exchange may require alternative forms of therapy. We report a case of one such patient who presented with TTP, whom we successfully managed with vincristine and responded favorably without the need for plasma exchange.
Dabak
Vrushali
V
Department of Hematology-Oncology, Henry Ford Hospital, Detroit, Michigan 48202, USA. vdabak1@hfhs.org
Kuriakose
Philip
P
Raman
Sundara
S
D000328:Adult; D005260:Female; D006801:Humans; D033221:Jehovah's Witnesses; D007770:L-Lactate Dehydrogenase / Q000378:metabolism; D010951:Plasma Exchange; D010956:Plasmapheresis; D010976:Platelet Count; D011697:Purpura, Thrombotic Thrombocytopenic / Q000628:therapy*; D013997:Time Factors; D016896:Treatment Outcome; D050257:Tubulin Modulators / Q000627:therapeutic use; D014750:Vincristine / Q000627:therapeutic use
D050257:Tubulin Modulators; D014750:Vincristine; D007770:L-Lactate Dehydrogenase