title: Use of a long-pulse alexandrite laser in the treatment of superficial pigmented lesions.
abstract: OBJECTIVE
  Although the alexandrite 755-nm-wavelength laser is effective in the treatment of unwanted hair, there are no published studies gauging the efficacy of the variable long-pulse alexandrite laser in the treatment of superficial pigmented lesions.
  
  
  METHODS
  Eighteen patients underwent a single treatment session using a variable pulse-width alexandrite laser. Test sites were performed using a 10-mm spot size and up to four pulse widths (3, 20, 40, 60 ms) with and without epidermal cooling. Full treatments were performed 3 weeks later using optimum test parameters. The patients were evaluated at 3 and 6 weeks.
  
  
  RESULTS
  Patients with darker lentigines had greater lesion clearance than those patients with lighter colored lentigines. Shorter pulse widths and treatment without cryogen cooling both, independently, lowered the fluence threshold for lentigo clearance.
  
  
  CONCLUSIONS
  A long-pulse alexandrite laser is effective in clearing solar lentigines in a single pass with minimal adverse effects.
authors: Dermatology Department, Naval Medical Center San Diego, San Diego, California, USA. john.trafeli@med.navy.mil
authors: John Paul
authors: JP
authors: Trafeli
authors: Julia M
authors: JM
authors: Kwan
authors: Kenneth J
authors: KJ
authors: Meehan
authors: Yacov
authors: Y
authors: Domankevitz
authors: Sandra
authors: S
authors: Gilbert
authors: Kenneth
authors: K
authors: Malomo
authors: Edward Victor
authors: EV
authors: Ross
mesh_terms: D000328:Adult; D000368:Aged; D006801:Humans; D053685:Laser Therapy; D053844:Lasers, Solid-State; D007911:Lentigo / Q000601:surgery*; D008875:Middle Aged