title: Successful pregnancy following double-frozen embryo transfer in a patient with repeated implantation failure.
abstract: OBJECTIVE
  To report a case of successful singleton pregnancy following a novel technique of sequential double transfer of two groups of frozen embryos at the same developmental stage (8-cell) at 5 and 7 days after the LH surge to a patient with seven previous failed assisted reproductive technology (ART) cycles.
  
  
  METHODS
  Case report.
  
  
  METHODS
  University of Toronto affiliated infertility clinic.
  
  
  METHODS
  A 27-year-old female with a three-year history of primary infertility.
  
  
  METHODS
  Double frozen embryo transfer of day-3 embryos two days apart in the luteal phase.
  
  
  METHODS
  Successful pregnancy.
  
  
  RESULTS
  Successful singleton pregnancy resulting in the delivery of healthy baby boy.
  
  
  CONCLUSIONS
  To the best of our knowledge, the patient is the first to be treated successfully with double frozen-embryo transfer.
authors: Toronto Centre for Advanced Reproductive Technology, Toronto, Canada. nesfand@excite.com
authors: Navid
authors: N
authors: Esfandiari
authors: Joan
authors: J
authors: Coogan-Prewer
authors: Lynda
authors: L
authors: Gotlieb
authors: E Anne
authors: EA
authors: Claessens
authors: Robert F
authors: RF
authors: Casper
mesh_terms: D000328:Adult; D015925:Cryopreservation / Q000379:methods*; D046149:Embryo Culture Techniques / Q000379:methods*; D010064:Embryo Implantation; D004624:Embryo Transfer / Q000379:methods*; D005260:Female; D006801:Humans; D007247:Infertility, Female / Q000628:therapy*; D050498:Live Birth; D011247:Pregnancy; D016896:Treatment Outcome