DEET microencapsulation: a slow-release formulation enhancing the residual efficacy of bed nets against malaria vectors.
Textile materials treated with synthetic repellents have the potential to provide protection against insect disease vectors but lack the residual activity necessary to achieve a prolonged effect or to be cost-effective. DEET MC is a formulation of DEET (N,N diethyl-m-toluamide) in which the repellent is gradually released from a capsule that binds the repellent. An experiment carried out on DEET-treated mosquito netting showed that the formulation repels, inhibits blood-feeding and kills mosquitoes for a period of at least 6 months under laboratory conditions. Such formulations may have the potential for use on nets against pyrethroid-resistant mosquitoes or on clothing or bedding materials distributed in disasters, emergencies or refugee camp situations.
N'guessan
Raphael
R
London School of Hygiene and Tropical Medicine, London, UK. raphael.n'guessan@lshtm.ac.uk
Knols
Bart G J
BG
Pennetier
Cedric
C
Rowland
Mark
M
D000818:Animals; D000852:Anopheles; D001512:Bedding and Linens / Q000706:statistics & numerical data*; D003465:Culex; D003671:DEET / Q000008:administration & dosage*; D004339:Drug Compounding; D006801:Humans; D007299:Insect Bites and Stings / Q000469:parasitology; D007302:Insect Repellents / Q000008:administration & dosage; D007305:Insecticide Resistance; D008288:Malaria / Q000517:prevention & control*; D009032:Mosquito Control / Q000379:methods*; D011722:Pyrethrins; D013223:Statistics as Topic; D013997:Time Factors
D007302:Insect Repellents; D011722:Pyrethrins; D003671:DEET