title: Subcutaneous metastasis from a gastrointestinal stromal tumor of the stomach: a case report.
abstract: Gastrointestinal stromal tumors (GISTs) are rare mesenchymal neoplasms of the stomach, which account for approximately 3.6% of all gastric tumors. They may or may not be malignant. Malignant GIST rarely metastasizes to distant organs. We report a case of a gastric GIST diagnosed in a 69- year-old woman presented with a synchronous subcutaneous paraumbilical metastasis. Computed tomography (CT) scan demonstrated a space-occupying lesion arising from the gastric wall with a second well-circumscribed lesion in the subcutaneous tissue which infiltrated the aponeurosis of the right rectus abdominis. The patient underwent total gastrectomy and resection of the subcutaneous mass. Pathologic examination of the gastric tumor and subcutaneous mass showed histological and immunohistochemical characteristics of a GIST. The patient succumbed on the 4th postoperative day. Gastric stromal tumor metastasis must be taken into consideration in the differential diagnosis of a palpable paraumbilical mass in a patient diagnosed with malignant GIST.
authors: Department of Surgery, General Hospital of Alexandroupolis, Alexandroupolis, Greece. anagstav@mail.gr
authors: S
authors: S
authors: Anagnostoulis
authors: K
authors: K
authors: Mimidis
authors: V
authors: V
authors: Papadopoulos
authors: D
authors: D
authors: Papalazarou
authors: P
authors: P
authors: Argyropoulou
authors: C
authors: C
authors: Iakovidis
authors: A
authors: A
authors: Polychronidis
authors: A
authors: A
authors: Karayiannakis
authors: D K
authors: DK
authors: Filippou
authors: C
authors: C
authors: Simopoulos
mesh_terms: D000368:Aged; D017809:Fatal Outcome; D005260:Female; D046152:Gastrointestinal Stromal Tumors / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D006801:Humans; D009362:Neoplasm Metastasis; D013274:Stomach Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D040521:Subcutaneous Tissue / Q000473:pathology*