title: [Case of adult influenza type A virus-associated encephalopathy successfully treated with primary multidisciplinary treatments].
abstract: The patient in this study was a 43-year-old woman who had become unconscious after contracting influenza virus type A infection. Brain CT showed severe brain swelling. Brain MRI also showed brain edema with no specific abnormality on T2-weighted images. We diagnosed her as having influenza type A virus-associated encephalopahty and treated her with Oseltamivir, methylprednisolone pulse therapy, and a high dose of intravenous immunoglobulins. In addition, we treated her with hypothermia and a high dose of intravenous ATIII because of the severe brain swelling and possibility of DIC. After the treatments, brain swelling had improved, and she regained consciousness without any sequelae. Adult influenza virus-associated encephalopathy is rare. We were able to successfully treat our patient with primary multidisciplinary treatments without causing sequelae.
authors: Department of Neurology and Geriatrics, Gifu University Graduate School of Medicine.
authors: Takeo
authors: T
authors: Sakurai
authors: Akio
authors: A
authors: Kimura
authors: Yuji
authors: Y
authors: Tanaka
authors: Isao
authors: I
authors: Hozumi
authors: Shinji
authors: S
authors: Ogura
authors: Takashi
authors: T
authors: Inuzuka
mesh_terms: D000328:Adult; D000925:Anticoagulants / Q000008:administration & dosage; D000990:Antithrombin III / Q000008:administration & dosage; D000998:Antiviral Agents / Q000008:administration & dosage; D015415:Biomarkers / Q000097:blood; D001929:Brain Edema / Q000175:diagnosis / Q000209:etiology; D003131:Combined Modality Therapy; D004211:Disseminated Intravascular Coagulation / Q000209:etiology / Q000628:therapy; D018792:Encephalitis, Viral / Q000150:complications / Q000175:diagnosis / Q000628:therapy* / Q000821:virology; D005260:Female; D006801:Humans; D007036:Hypothermia, Induced; D016756:Immunoglobulins, Intravenous / Q000008:administration & dosage; D009980:Influenza A virus; D007251:Influenza, Human / Q000150:complications / Q000175:diagnosis / Q000628:therapy* / Q000821:virology; D015850:Interleukin-6 / Q000097:blood; D008279:Magnetic Resonance Imaging; D008775:Methylprednisolone / Q000008:administration & dosage; D053139:Oseltamivir / Q000008:administration & dosage; D020551:Pulse Therapy, Drug; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D014474:Unconsciousness / Q000209:etiology / Q000628:therapy
chemical_list: D000925:Anticoagulants; D000998:Antiviral Agents; D015415:Biomarkers; D016756:Immunoglobulins, Intravenous; D015850:Interleukin-6; D053139:Oseltamivir; D000990:Antithrombin III; D008775:Methylprednisolone