Commentary on the clinical relevance of concentration/QTc relationships for new drug candidates.
Bloomfield
Daniel
D
Merck Research Laboratories, 126 East Lincoln Avenue, Mail Code: RY34-A224, Rahway, NJ 07065-0900, USA. daniel_bloomfield@merck.com
Krishna
Rajesh
R
D002317:Cardiovascular Agents / Q000009:adverse effects; D004305:Dose-Response Relationship, Drug; D015507:Drugs, Investigational / Q000009:adverse effects*; D017408:Guidelines as Topic; D006801:Humans; D008133:Long QT Syndrome / Q000139:chemically induced* / Q000175:diagnosis; D018570:Risk Assessment / Q000379:methods
D002317:Cardiovascular Agents; D015507:Drugs, Investigational