Choroidal drainage in the management of acute angle closure after topiramate toxicity.
OBJECTIVE
To report the role of choroidal drainage in patient with acute bilateral angle closure secondary to cilio-choroidal effusion with Topiramate.


METHODS
Interventional case report.


METHODS
Two weeks after commencing tablet Topiramate (Sulfamate derivative) for management of epilepsy, a patient developed bilateral acute angle closure secondary to cilio-choroidal effusion with lenticulo-corneal touches for which choroidal drainage was performed in 1 eye.


RESULTS
After choroidal drainage, anterior chamber deepened, corneal edema resolved, choroidals started resolving, and intraocular pressure was controlled without medication.


CONCLUSIONS
In patients presenting with acute angle closure secondary to Topiramate toxicity, choroidal drainage if indicated, is a safe and effective interventional procedure.
Parikh
Rajul
R
L. V. Prasad Eye Institute, Hyderabad, Andhra Pradesh, India. rajulparikh@lvpei.org
Parikh
Shefali
S
Das
Sanghamitra
S
Thomas
Ravi
R
D000927:Anticonvulsants / Q000009:adverse effects* / Q000627:therapeutic use; D015862:Choroid Diseases / Q000139:chemically induced* / Q000150:complications* / Q000628:therapy; D015715:Corneal Edema / Q000139:chemically induced / Q000503:physiopathology; D004322:Drainage; D004827:Epilepsy / Q000188:drug therapy; D005632:Fructose / Q000009:adverse effects / Q000031:analogs & derivatives* / Q000627:therapeutic use; D015812:Glaucoma, Angle-Closure / Q000000981:diagnostic imaging / Q000209:etiology* / Q000503:physiopathology; D006801:Humans; D007429:Intraocular Pressure; D008297:Male; D033401:Microscopy, Acoustic; D008875:Middle Aged; D000077236:Topiramate; D016896:Treatment Outcome; D014463:Ultrasonography
D000927:Anticonvulsants; D000077236:Topiramate; D005632:Fructose