[Advances in standardization and quality control for the analysis of sperm quality parameters].
Semen analysis is a basic test to evaluate male reproductive function. In recent years, urgent needs for the standardization of semen analysis have been emphasized among andrologists worldwide. This review discusses the standardization and quality control (QC) for the analysis of sperm quality parameters, including sperm concentration, motility and morphology. The key to sperm concentration analysis is the standardization of sperm-counting chamber, thus Cell-VU chamber may be the first choice. The analysis of sperm motility and morphology is too subjective to be reliable. Therefore, the computer-aided semen analysis (CASA) system may be the final selection. QC of semen analysis mainly lies in the selection of QC materials and the administration of external QC and internal QC. Meanwhile, the charts and arithmetic methods should be established to monitor QC of semen analysis.
Huang
Yu-feng
YF
PLA Research Institute of Clinical Laboratory Medicine, Nanjing General Hospital of Nanjing Command, PLA, Nanjing, Jiangsu 210002, China. huangyf@androl.cn
Lu
Jin-chun
JC
D006801:Humans; D008297:Male; D011786:Quality Control; D012015:Reference Standards; D012661:Semen / Q000166:cytology*; D013076:Sperm Count / Q000295:instrumentation* / Q000592:standards* / Q000706:statistics & numerical data; D013081:Sperm Motility; D013094:Spermatozoa / Q000166:cytology* / Q000502:physiology