title: Estimated number of cases, regional distribution and survival of patients diagnosed with acute myeloid leukemia between 1996 and 2000 in Rio Grande do Sul, Brazil.
abstract: Rio Grande do Sul (RS), in South Brazil, with about 10 million inhabitants, is known for its agricultural activities and consequent increased human exposure to toxic agents. Patients with de novo acute myeloid leukemia (AML) were included based on information retrieved from all referral hospitals in RS between 1996 and 2000. A total of 532 patients were registered. Median age at diagnosis was 42 years. The estimated annual incidence was 1.11 cases/100,000 inhabitants/year. There was an estimated incidence of 0.5-1 case per 100,000 inhabitants up to the age of 45 years, and of 3.5 cases per 100,000 inhabitants aged 70 years and older, with no geographical clusters. The mean 5-year survival rate was 17% for all cases. There was an increased number of M3 cases, as already described for individuals of Latin-American and the mortality rate was similar to that described in the literature.
authors: Division of Hematology and Bone Marrow Transplantation, Hospital de Clínicas de Porto Alegre, Programa de Pós-Graduação em Clínica medica da Universidade Federal do Rio Grande do Sul. marcelocapra@hotmail.com
authors: Marcelo
authors: M
authors: Capra
authors: Líbia
authors: L
authors: Vilella
authors: Waldir Veiga
authors: WV
authors: Pereira
authors: Virgínia Maria
authors: VM
authors: Coser
authors: Mário Sérgio
authors: MS
authors: Fernandes
authors: Marco Antônio
authors: MA
authors: Schilling
authors: Denise
authors: D
authors: Almeida
authors: Mauro
authors: M
authors: Gross
authors: Márcia
authors: M
authors: Leite
authors: Tânia
authors: T
authors: Hellwig
authors: Gilca
authors: G
authors: Natchigal
authors: Alice
authors: A
authors: Zelmanowicz
authors: Giorgio
authors: G
authors: Paskulin
authors: Jorge
authors: J
authors: Neumann
authors: Lúcia
authors: L
authors: Silla
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001938:Brazil / Q000453:epidemiology; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D015994:Incidence; D007223:Infant; D007231:Infant, Newborn; D015470:Leukemia, Myeloid, Acute / Q000453:epidemiology* / Q000401:mortality; D008297:Male; D008875:Middle Aged; D013997:Time Factors