title: [Pulmonary malakoplakia and Rhodococcus equi infection. A report of two cases and review].
abstract: Malakoplakia is a rare, chronic, granulomatous disease seen in immunocompromised patients, caused by multiple infectious agents, most often bacteria. Microscopically, accumulations of macrophages with granular cytoplasm and intra- or extracellular structures, called Michaelis-Gutmann bodies are characteristic. Main cause of pulmonary malakoplakia is Rhodococcus equi infection. We report two cases of pulmonary malakoplakia, in one case R. equi infection was confirmed. We also present a summary of recent knowledge about the pathogenesis, morphology and clinical course of the disease.
authors: Zakład Patomorfologii, Instytut Gruźlicy i Chorób Płuc, ul. Płocka 26, 01-138 Warszawa, Poland. m.szolkowska@igichp.edu.pl
authors: Małgorzata
authors: M
authors: Szołkowska
authors: Renata
authors: R
authors: Langfort
authors: Ewa M
authors: EM
authors: Szczepulska
authors: Iwona
authors: I
authors: Bestry
authors: Jarosław
authors: J
authors: Religioni
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000382:microbiology / Q000473:pathology*; D000193:Actinomycetales Infections / Q000150:complications / Q000382:microbiology / Q000473:pathology* / Q000628:therapy; D000328:Adult; D006801:Humans; D016867:Immunocompromised Host; D008171:Lung Diseases / Q000382:microbiology / Q000473:pathology* / Q000628:therapy; D008287:Malacoplakia / Q000209:etiology / Q000473:pathology* / Q000628:therapy; D008297:Male; D011379:Prognosis; D016929:Rhodococcus equi / Q000302:isolation & purification; D012307:Risk Factors