Gene prediction: compare and CONTRAST.
CONTRAST, a new gene-prediction algorithm that uses sophisticated machine-learning techniques, has pushed de novo prediction accuracy to new heights, and has significantly closed the gap between de novo and evidence-based methods for human genome annotation.
Flicek
Paul
P
European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB101SD, UK. flicek@ebi.ac.uk
D000818:Animals; D001185:Artificial Intelligence; D019295:Computational Biology / Q000379:methods*; D020224:Expressed Sequence Tags; D016678:Genome; D006801:Humans; D016415:Sequence Alignment / Q000379:methods*; D012984:Software