The Mucin degrader Akkermansia muciniphila is an abundant resident of the human intestinal tract.
A 16S rRNA-targeted probe, MUC-1437, was designed and validated in order to determine the presence and numbers of cells of Akkermansia muciniphila, a mucin degrader, in the human intestinal tract. As determined by fluorescent in situ hybridization, A. muciniphila accounted more than 1% of the total fecal cells and was shown to be a common bacterial component of the human intestinal tract.
Derrien
Muriel
M
Laboratory of Microbiology, Dreijenplein 10, 6703 HB Wageningen, The Netherlands. muriel.derrien@wur.nl
Collado
M Carmen
MC
Ben-Amor
Kaouther
K
Salminen
Seppo
S
de Vos
Willem M
WM
D001419:Bacteria / Q000235:genetics / Q000378:metabolism*; D019295:Computational Biology; D017931:DNA Primers / Q000235:genetics; D005243:Feces / Q000382:microbiology*; D005434:Flow Cytometry; D005752:Gastric Mucins / Q000378:metabolism*; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D007422:Intestines / Q000382:microbiology*; D015345:Oligonucleotide Probes / Q000235:genetics; D010802:Phylogeny; D012336:RNA, Ribosomal, 16S / Q000235:genetics
D017931:DNA Primers; D005752:Gastric Mucins; D015345:Oligonucleotide Probes; D012336:RNA, Ribosomal, 16S