Skin metastases revealing a bilateral ovarian invasive micropapillary serous carcinoma.
Skin involvement is a late complication that rarely occurs in ovarian cancer patients. This event invariably carries a bad prognosis in the course of an advanced stage ovarian carcinoma which is usually of the conventional serous type. Micropapillary serous carcinoma (MPSC) was recently recognized as a distinct neoplasm that seems to be less aggressive than conventional serous ovarian carcinoma. Indeed, a few cases of stage IV MPSC have been reported. Herein, we describe an unusual case of ovarian invasive MPSC occurring in a young woman, particularly by its mode of presentation as multiple subcutaneous nodules that were subsequently diagnosed as metastatic lesions. This case demonstrates the potential of MPSC for aggressive clinical behaviour.
Moussa
Adnène
A
Department of Pathology, Fattouma Bourguiba University Hospital, 5019 Monastir, Tunisia.
Denguezli
Walid
W
Njim
Leïla
L
Haddad
Anis
A
Faleh
Raja
R
Sakouhi
Mohamed
M
Zakhama
Abdelfattah
A
D000328:Adult; D001062:Appendectomy; D017024:Chemotherapy, Adjuvant; D018283:Cystadenocarcinoma, Papillary / Q000175:diagnosis* / Q000628:therapy; D018284:Cystadenocarcinoma, Serous / Q000175:diagnosis* / Q000628:therapy; D005187:Fallopian Tubes / Q000601:surgery; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007044:Hysterectomy; D009361:Neoplasm Invasiveness; D009852:Omentum / Q000601:surgery; D010051:Ovarian Neoplasms / Q000175:diagnosis* / Q000628:therapy; D010052:Ovariectomy; D012878:Skin Neoplasms / Q000175:diagnosis / Q000556:secondary* / Q000628:therapy