title: Glycopolydiacetylene nanoparticles as a chromatic biosensor to detect Shiga-like toxin producing Escherichia coli O157:H7.
abstract: Shiga toxin-producing Escherichia coli organisms (STEC) were detected by Gal-alpha1,4-Gal glycopolydiacetylene (GPDA) nanoparticles through the selective binding between Shiga toxin and GPDA nanoparticles. The binding produced a colorimetric change in the absorption wavelength of the GPDA nanoparticles. This method provides a highly selective, rapid, sensitive, and quantitative approach for the detection of STEC.
authors: ATERIS Technologies, Bozeman, MT 59718, USA. wang.892@osu.edu
authors: Jon O
authors: JO
authors: Nagy
authors: Yalong
authors: Y
authors: Zhang
authors: Wen
authors: W
authors: Yi
authors: Xianwei
authors: X
authors: Liu
authors: Edwin
authors: E
authors: Motari
authors: Jing Catherine
authors: JC
authors: Song
authors: Jeffrey T
authors: JT
authors: Lejeune
authors: Peng George
authors: PG
authors: Wang
mesh_terms: D015374:Biosensing Techniques; D019453:Escherichia coli O157 / Q000302:isolation & purification* / Q000378:metabolism; D053758:Nanoparticles; D000078789:Polyacetylene Polymer; D011108:Polymers; D053279:Polyynes; D022603:Shiga Toxins / Q000096:biosynthesis*
chemical_list: D000078789:Polyacetylene Polymer; D011108:Polymers; D022603:Shiga Toxins; D053279:Polyynes; C082361:polydiacetylene