title: Familial association of laryngeal, lung, stomach and early-onset breast cancer.
abstract: This study analyzes the incidence of different types of cancer among 2839 first-degree relatives of 760 consecutive, unselected laryngeal cancer patients, compared with the general population. A statistically significant excess was seen for other cancers of the larynx (SIR: 400), lung (SIR: 135) and stomach (SIR: 271), and early-onset breast cancer (SIR: 287). Familial laryngeal cancer may not be a single site-specific cancer syndrome.
authors: Department of Otolaryngology and Laryngological Oncology, Pomeranian Medical University, Szczecin, Poland. jaworowska@tlen.pl
authors: Ewa
authors: E
authors: Jaworowska
authors: Pablo
authors: P
authors: Serrano-Fernández
authors: Czesława
authors: C
authors: Tarnowska
authors: Jakub
authors: J
authors: Lubiński
authors: Marek
authors: M
authors: Brzosko
authors: Jacek
authors: J
authors: Flicinski
authors: Bartołomej
authors: B
authors: Masojc
authors: Joanna
authors: J
authors: Matyjasik
authors: Rodney J
authors: RJ
authors: Scott
authors: Steven A
authors: SA
authors: Narod
authors: Jan
authors: J
authors: Lubiński
mesh_terms: D000328:Adult; D017668:Age of Onset; D000368:Aged; D001943:Breast Neoplasms / Q000453:epidemiology* / Q000235:genetics; D005192:Family Health; D005260:Female; D006801:Humans; D007822:Laryngeal Neoplasms / Q000453:epidemiology* / Q000235:genetics; D008175:Lung Neoplasms / Q000453:epidemiology* / Q000235:genetics; D008297:Male; D008875:Middle Aged; D011044:Poland; D012737:Sex Factors; D013274:Stomach Neoplasms / Q000453:epidemiology* / Q000235:genetics; D013577:Syndrome