title: [Primary cutaneous infections due to Staphylococcus and Streptococcus].
abstract: Pyodermitis constitutes a very important chapter in dermatological practice. Its pathogenesis, in special the one caused by S. aureus, has improved due to the knowledge of the role developed by the host defensins, quorum-sensing signaling and the Panton-Valentine leucocidin gene among others. As well, exfoliative toxins and enterotoxins responsible for the staphylococal scalded skin syndrome (SSSS) and toxic shock syndrome, respectively, have been cloned. Also, it has been seen that bullous impetigo, SSSS and pemphigus foliaceus share a common target: desmoglein-1. The Panton-Valentine leucocidin gene has been related to the appearance of abscesses, necrotic cutaneous lesions and furuncles in young persons caused by meticillin resistant S. aureus, with its epidemiological implications. Finally, some atypical forms of erysipelas suppose a diagnostic challenge for the dermatologist.
authors: Servicio de Dermatología, Hospital Universitario de La Princesa, Madrid, España. maragues@aedv.es
authors: M
authors: M
authors: Aragüés
authors: A
authors: A
authors: González-Arriba
mesh_terms: D001427:Bacterial Toxins / Q000009:adverse effects / Q000235:genetics / Q000302:isolation & purification; D005499:Folliculitis / Q000382:microbiology; D006801:Humans; D008205:Lymphangitis / Q000382:microbiology; D055624:Methicillin-Resistant Staphylococcus aureus / Q000187:drug effects / Q000302:isolation & purification / Q000502:physiology; D009260:Nail Diseases / Q000382:microbiology; D053038:Quorum Sensing; D012772:Shock, Septic / Q000453:epidemiology / Q000382:microbiology; D012867:Skin / Q000382:microbiology; D017192:Skin Diseases, Bacterial / Q000175:diagnosis / Q000453:epidemiology / Q000276:immunology / Q000382:microbiology*; D013207:Staphylococcal Skin Infections / Q000145:classification / Q000175:diagnosis / Q000453:epidemiology / Q000276:immunology / Q000382:microbiology*; D013210:Staphylococcus / Q000187:drug effects / Q000235:genetics / Q000302:isolation & purification / Q000502:physiology*; D013290:Streptococcal Infections / Q000175:diagnosis / Q000453:epidemiology / Q000276:immunology / Q000382:microbiology*; D013291:Streptococcus / Q000187:drug effects / Q000235:genetics / Q000302:isolation & purification / Q000502:physiology*; D014774:Virulence
chemical_list: D001427:Bacterial Toxins