[Comparison of neuroprotective properties of nootropes, calcium channel blockers, and panangin].
Neuroprotective properties of a series of drugs including nootropes, calcium channel antagonists, and panangin have been studied on a model of craniocerebral trauma. It is established that beglimin and nooglutil exhibit a moderate antiischemic, antihypoxic, and antiamnesic action in posttraumatic period; panangin possesses antiischemic, anticonvulsant, and antiamnesic properties; while nimodipin exhibit only antiamnesic action. It is concluded that beglimin, nooglutil and panangin are of importance in the pharmacological treatment of secondary traumatic brain injury.
Belozertsev
F Iu
FIu
Belozertsev
Iu A
IuA
Slobodeniuk
T F
TF
Iuntsev
S V
SV
Shabel'skaia
V V
VV
D000818:Animals; D001362:Avoidance Learning / Q000187:drug effects; D002545:Brain Ischemia / Q000209:etiology / Q000517:prevention & control / Q000523:psychology; D002121:Calcium Channel Blockers / Q000494:pharmacology*; D003071:Cognition / Q000187:drug effects; D006259:Craniocerebral Trauma / Q000150:complications; D002534:Hypoxia, Brain / Q000209:etiology / Q000517:prevention & control / Q000523:psychology; D051379:Mice; D008808:Mice, Inbred CBA; D018696:Neuroprotective Agents / Q000494:pharmacology*; D018697:Nootropic Agents / Q000494:pharmacology*; D011195:Potassium Magnesium Aspartate / Q000494:pharmacology*; D051381:Rats; D017208:Rats, Wistar; D012640:Seizures / Q000209:etiology / Q000517:prevention & control
D002121:Calcium Channel Blockers; D018696:Neuroprotective Agents; D018697:Nootropic Agents; D011195:Potassium Magnesium Aspartate