Aberration-correcting effect of ThinOptX IOL.
OBJECTIVE
To evaluate spherical aberration and visual function after microincision cataract surgery using the ThinOptX rollable intraocular lens.


METHODS
Prospective, comparative, and interventional case series.


METHODS
SettingSingle-centre institutional practice. This prospective study evaluated 58 patients with cataracts who underwent bimanual microphaco cataract surgery in both eyes. A ThinOptX lens was introduced into one eye and an Alcon Acrysof lens, as a control, into the other. One month after cataract surgery, the corneal, whole-eye, and internal spherical aberration, and contrast sensitivity in both eyes were measured. We also measured the spherical aberration in artificial model eyes bearing Acrysof and ThinOptX lenses. Two-sided paired t-test was used for assessing all data.


RESULTS
The root mean square (RMS) for both whole-eye and internal spherical aberrations was smaller in eyes bearing ThinOptX (P=0.03 and P=0.07, respectively). Although there was no statistically significant difference in the RMS for internal spherical aberration between ThinOptX- and Acrysof-bearing eyes, according to the Zernike polynomial expansion, all human and model eyes bearing ThinOptX registered negative internal spherical aberration in Z(4,0) and Z(6,0). On the other hand, all human and model eyes bearing Acrysof registered positive internal spherical aberration in Z(4,0) and Z(6,0). The ThinOptX lens yielded slightly higher contrast sensitivity in all cycles.


CONCLUSIONS
As the ThinOptX lens is designed for negative spherical aberration, we encountered smaller whole spherical aberrations and higher contrast sensitivity than with the Acrysof lens. The implantation of ThinOptX IOL after microincision cataract surgery yielded good visual function.
Ouchi
M
M
Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan. mouchi@ophth.kpu-m.ac.jp
Kinoshita
S
S
D000368:Aged; D015350:Contrast Sensitivity; D019781:Corneal Topography / Q000379:methods; D057108:Corneal Wavefront Aberration / Q000517:prevention & control; D004728:Endothelium, Corneal / Q000473:pathology; D006801:Humans; D019654:Lens Implantation, Intraocular / Q000379:methods; D007910:Lenses, Intraocular; D008866:Microsurgery / Q000379:methods; D008875:Middle Aged; D008953:Models, Anatomic; D018918:Phacoemulsification / Q000379:methods*; D011446:Prospective Studies; D011474:Prosthesis Design; D012030:Refractive Errors / Q000517:prevention & control*; D014792:Visual Acuity