Recurrent intracranial solitary fibrous tumor initially diagnosed as hemangiopericytoma.
We describe a case of an intracranial solitary fibrous tumor that recurred three times consecutively in an 11-year period. A 72-year-old man presented with a headache and gait disturbance. Magnetic resonance imaging (MRI) revealed a dumbbell tumor at the left tentorium. The tumor was removed but recurred. The first diagnosis was hemangiopericytoma, but all specimens showed a "patternless pattern" and few reticulin fibers, which features were not compatible with hemangiopericytoma. All tumors showed immunoreactivity for CD34 and bcl-2. These results point to a solitary fibrous tumor (SFT) and not to hemangiopericytoma. We present here a hypercellular spindle-cell tumor that was very similar to hemangiopericytoma but is better diagnosed as SFT.
Hori
Emiko
E
Department of Neurosurgery, Saito Memorial Hospital, Niigata, Japan.
Kurimoto
Masanori
M
Fukuda
Osamu
O
Takahashi
Chiaki
C
Nagai
Shoichi
S
Oya
Takeshi
T
Endo
Shunro
S
D000368:Aged; D000369:Aged, 80 and over; D018952:Antigens, CD34 / Q000096:biosynthesis; D001932:Brain Neoplasms / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D003951:Diagnostic Errors; D006393:Hemangiopericytoma / Q000473:pathology*; D006801:Humans; D007150:Immunohistochemistry; D008279:Magnetic Resonance Imaging; D008297:Male; D018396:Mucin-1 / Q000096:biosynthesis; D009364:Neoplasm Recurrence, Local / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D019253:Proto-Oncogene Proteins c-bcl-2 / Q000096:biosynthesis; D054364:Solitary Fibrous Tumors / Q000378:metabolism / Q000473:pathology* / Q000601:surgery
D018952:Antigens, CD34; D018396:Mucin-1; D019253:Proto-Oncogene Proteins c-bcl-2