Therapeutic agents in perioperative third molar surgical procedures.
Surgical extraction of third molars is one of the most common of all surgical procedures. The outcome of third molar surgery includes pain, trismus, edema, nausea, infection, and alveolar osteitis. The intent of this article is to provide a literature review and analysis of the various chemotherapeutic agents used to control, minimize, or eliminate these outcomes. Unfortunately, comparison of the published studies represents a tremendous challenge because of the variability in parameters and methods used for each study. A trend does exist among many of the current researchers, who realize that randomized, controlled, evidence-based research rather than personal experience is necessary to develop appropriate guidelines for using chemotherapeutic agents.
Mehrabi
Mehran
M
Division of Oral and Maxillofacial Surgery, Emory University School of Medicine, 1365-B Clifton Road NE, Suite 2300-B, Atlanta, GA 30322, USA.
Allen
John M
JM
Roser
Steven M
SM
D000700:Analgesics / Q000627:therapeutic use; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D000932:Antiemetics / Q000627:therapeutic use; D006801:Humans; D008964:Molar, Third / Q000601:surgery*; D053210:Pharmaceutical Preparations, Dental / Q000627:therapeutic use*; D008517:Phytotherapy; D011183:Postoperative Complications / Q000517:prevention & control*; D017410:Practice Guidelines as Topic; D016032:Randomized Controlled Trials as Topic
D000700:Analgesics; D000900:Anti-Bacterial Agents; D000893:Anti-Inflammatory Agents; D000932:Antiemetics; D053210:Pharmaceutical Preparations, Dental