2',3'-isopropylidene group, a molecular scaffold to study the activity of adenosine and adenylate deaminase on adenosine analogues modified in the ribose moiety.
2 ',3 '-Isopropylidene group can be used as a molecular scaffold for the introduction of modifications at 5 ' and 1 ' positions of adenosine and these modified nucleosides are used to evaluate the biocatalytic activity of adenosine and adenylate deaminase.
Ciuffreda
Pierangela
P
Dipartimento di Scienze Precliniche LITA Vialba, Università degli Studi di Milano, via G.B. Grassi 74, 20157 Milan, Italy. pierangela.ciuffreda@unimi.it
Alessandrini
Laura
L
Santaniello
Enzo
E
D000659:AMP Deaminase / Q000737:chemistry*; D000241:Adenosine / Q000031:analogs & derivatives* / Q000737:chemistry; D000243:Adenosine Deaminase / Q000737:chemistry*; D012266:Ribose / Q000737:chemistry*
C014626:2',3'-isopropylideneadenosine; D012266:Ribose; D000243:Adenosine Deaminase; D000659:AMP Deaminase; D000241:Adenosine