Unexplained polyarthralgia and celiac disease.
Celiac disease is an immunological disorder whose best-known manifestations are gastrointestinal symptoms. However, early joint manifestations are common and frequently overlooked features of celiac disease. We report a case in which unexplained inflammatory polyarthralgia and iron-deficiency anemia led to the diagnosis of celiac disease. Autoimmune thyroiditis was also a feature. Early diagnosis and treatment of celiac disease protect patients against complications such as digestive neoplasis. A simple and rapid tool for achieving the early diagnosis is the measurement of the serum of anti-gliadin, anti-endomysial and anti-tissue transglutaminase antibodies. However, a duodenal biopsy remains the only means of making the definitive diagnosis of celiac disease.
Dawidowicz
Karen
K
Rheumatology Federation, Lariboisière Teaching Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France.
Ea
Hang-Korng
HK
Lahalle
Sophie
S
Qubaja
Marwan
M
Lioté
Frédéric
F
D000328:Adult; D018798:Anemia, Iron-Deficiency / Q000209:etiology; D018771:Arthralgia / Q000209:etiology*; D002446:Celiac Disease / Q000150:complications / Q000175:diagnosis*; D005260:Female; D006801:Humans