title: Health care-associated endocarditis caused by Staphylococcus aureus with reduced susceptibility to vancomycin.
abstract: Infective endocarditis (IE) caused by methicillin-resistant Staphylococcus aureus with reduced vancomycin susceptibility (SARV) has been reported worldwide. We report the successful treatment of a pediatric patient with SARV IE and characterization of the infecting strain. The MIC of vancomycin rose from 1.5 to 2 microg/ml, and the SARV was confirmed by population analysis.
authors: Division of Clinical Research, National Health Research Institutes, Tainan, Taiwan.
authors: Chia-Yu
authors: CY
authors: Chi
authors: Tsai-Ling
authors: TL
authors: Lauderdale
authors: Shih-Min
authors: SM
authors: Wang
authors: Jing-Ming
authors: JM
authors: Wu
authors: Yu-Jen
authors: YJ
authors: Yang
authors: Ching-Chuan
authors: CC
authors: Liu
mesh_terms: D000081:Acetamides / Q000627:therapeutic use; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002675:Child, Preschool; D003428:Cross Infection / Q000188:drug therapy / Q000382:microbiology*; D004697:Endocarditis, Bacterial / Q000188:drug therapy / Q000382:microbiology*; D005260:Female; D005672:Fusidic Acid / Q000627:therapeutic use; D006801:Humans; D000069349:Linezolid; D016106:Methicillin Resistance; D008826:Microbial Sensitivity Tests; D023303:Oxazolidinones / Q000627:therapeutic use; D013203:Staphylococcal Infections / Q000188:drug therapy / Q000382:microbiology*; D013211:Staphylococcus aureus / Q000187:drug effects* / Q000302:isolation & purification; D020713:Vancomycin Resistance
chemical_list: D000081:Acetamides; D000900:Anti-Bacterial Agents; D023303:Oxazolidinones; D005672:Fusidic Acid; D000069349:Linezolid