Endometrial stromal nodule embedded into term placenta.
A 28-year-old patient presented with a 5 cm endometrial stromal tumor situated at the uteroplacental interface, which was diagnosed ultrasonographically at the 28th week of pregnancy. The tumor was asymptomatic and closely attached to the decidua; after a normal term delivery, it was revealed to be embedded within the placenta. Microscopically, the neoplasm had a high mitotic rate and characteristic features of endometrial stromal tumor, such as CD10, progesterone receptor positivity, and an expansile linear, non-infiltrative pushing border. There were also pregnancy-related changes such as decidualization and myxoid change. In conclusion, the lesion was considered a benign endometrial stromal nodule with an unusual morphology and increased proliferation rate due to the hormonal stimuli of pregnancy.
Karpf
Eva F
EF
Institute of Pathology, Medical University of Graz, Graz, Austria. eva.karpf@meduni-graz.at
Poetsch
Bernhard
B
Langner
Cord
C
Nogales
Francisco F
FF
Regauer
Sigrid
S
D000328:Adult; D016889:Endometrial Neoplasms / Q000000981:diagnostic imaging*; D005260:Female; D046152:Gastrointestinal Stromal Tumors / Q000000981:diagnostic imaging*; D006801:Humans; D007231:Infant, Newborn; D010920:Placenta / Q000000981:diagnostic imaging / Q000473:pathology*; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000000981:diagnostic imaging*; D011263:Pregnancy Trimester, Third; D014463:Ultrasonography