Heart failure in diabetes and related conditions.
BACKGROUND
Despite advances in therapy for congestive heart failure (CHF), mortality remains 40% to 80% higher for diabetics with CHF than nondiabetics. Diabetes prevalence is increasing worldwide with prevalence of diabetes among patients with CHF increasing at an even faster pace.


RESULTS
Although multiple mechanisms are responsible for development of CHF in diabetes, ischemic heart disease plays a major role. In the foreseeable future, physicians will have to deal with increasing numbers of subjects with diabetes, coronary disease, and heart failure. Several recent developments in the field of heart failure have revolutionized the way patients are treated for CHF with improvements in quality of life and mortality. Although long-term prospective studies specifically addressing heart failure in diabetes are lacking, extrapolation of data from recent large trials has shed light on management of CHF in diabetes.


CONCLUSIONS
This review summarizes new developments in the field of CHF among subjects with diabetes, metabolic syndrome, and obesity.
Kamalesh
Masoor
M
Department of Clinical Cardiology Research, VA Medical Center, Indiana University School of Medicine, Indianapolis, Indiana, USA.
D048909:Diabetes Complications / Q000150:complications* / Q000453:epidemiology; D006333:Heart Failure / Q000150:complications / Q000453:epidemiology*; D006801:Humans; D015994:Incidence; D024821:Metabolic Syndrome / Q000150:complications* / Q000453:epidemiology; D009765:Obesity / Q000150:complications* / Q000453:epidemiology; D011379:Prognosis; D015996:Survival Rate / Q000639:trends; D014481:United States / Q000453:epidemiology