[Mycobacterium ulcerans infection treated by Rifater, pyrazynamide, Myambutol, and surgery: a case report with a 6-year follow-up].
The author reports a case of pleuritis associated with a large homolateral Buruli thorax ulcer in a nine-year old female patient, in the Democratic Republic of Congo. Smears on Ziehl-Neelsen revealed acid-alcohol-resistant bacilli. The pathological histology confirmed a Mycobacterium ulcerans infection (Buruli ulcer). The treatment was surgical (excision-dressing-grafting) associated to antibiotic therapy (Rifater, Pyrazynamide, and Myambutol). After six years of follow up, no relapse was observed.
Kibadi
K
K
Département de Chirurgie, Cliniques Universitaires, Université de Kinshasa, Kinshasa XI, Democratic Republic of Congo. akibadi@yahoo.fr
D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D054312:Buruli Ulcer / Q000188:drug therapy* / Q000601:surgery; D002648:Child; D002700:Chloramines / Q000008:administration & dosage / Q000627:therapeutic use; D003131:Combined Modality Therapy; D004338:Drug Combinations; D004359:Drug Therapy, Combination; D004977:Ethambutol / Q000008:administration & dosage / Q000627:therapeutic use*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007538:Isoniazid / Q000008:administration & dosage / Q000627:therapeutic use*; D008408:Mastectomy; D008795:Metronidazole / Q000008:administration & dosage / Q000627:therapeutic use; D019911:Mycobacterium ulcerans / Q000187:drug effects; D009582:Nitrofurantoin / Q000008:administration & dosage / Q000627:therapeutic use; D010998:Pleurisy / Q000188:drug therapy* / Q000382:microbiology / Q000601:surgery; D011239:Prednisolone / Q000008:administration & dosage / Q000627:therapeutic use; D011718:Pyrazinamide / Q000008:administration & dosage / Q000627:therapeutic use*; D012008:Recurrence; D012293:Rifampin / Q000008:administration & dosage / Q000627:therapeutic use*; D016038:Skin Transplantation
D000900:Anti-Bacterial Agents; D002700:Chloramines; D004338:Drug Combinations; C087181:isoniazid, pyrazinamide, rifampin drug combination; D008795:Metronidazole; D011718:Pyrazinamide; D004977:Ethambutol; D009582:Nitrofurantoin; D011239:Prednisolone; C030816:chloramine; D007538:Isoniazid; D012293:Rifampin