title: Chemical synthesis of dolichyl phosphates, their analogues and derivatives and application of these compounds in biochemical assays.
abstract: Several methods for simple and efficient chemical synthesis of dolichyl phosphates and their analogues and derivatives are briefly summarized with a special emphasis on chemical modification of phosphoryl group and preparation of dolichyl phosphates labelled at the omega-end and at the gamma-isoprene unit of the isoprene chain by fluorescent groups, 2-aminopyridine and 1-aminonaphtalene residues. Additionally, data on biochemical assays with application of the compounds mentioned above are presented.
authors: N.K. Kochetkov Laboratory of Carbohydrate Chemistry, N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russia.
authors: Leonid L
authors: LL
authors: Danilov
authors: Tatyana N
authors: TN
authors: Druzhinina
mesh_terms: D000438:Alcohols / Q000737:chemistry; D004288:Dolichol Phosphates / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D000438:Alcohols; D004288:Dolichol Phosphates; C028306:dolichol monophosphate