Evidence for strict inpatient blood glucose control: time to revise glycemic goals in hospitalized patients.
Inpatient hyperglycemia in patients with and without a history of diabetes is common and is associated with increased hospital morbidity and mortality. The objectives of this communication are to examine results of randomized clinical trials of strict inpatient glucose control in medical and surgical intensive care units and to provide guidelines for achieving and maintaining glycemic control in patients admitted to critical and noncritical settings. We propose a more conservative approach of glycemic control than current American Association of Clinical Endocrinology recommendations until results of prospective, multicenter, randomized studies become available.
Kitabchi
Abbas E
AE
University of Tennessee Health Science Center, Memphis, TN 38163, USA. akitabchi@utmem.edu
Freire
Amado X
AX
Umpierrez
Guillermo E
GE
D001786:Blood Glucose / Q000378:metabolism*; D017052:Hospital Mortality; D006801:Humans; D006943:Hyperglycemia / Q000453:epidemiology / Q000209:etiology; D007297:Inpatients; D008991:Monitoring, Physiologic / Q000379:methods* / Q000592:standards; D009017:Morbidity; D009203:Myocardial Infarction / Q000097:blood; D016032:Randomized Controlled Trials as Topic
D001786:Blood Glucose