title: [A case of angiosarcoma of pelvis with pulmonary metastases which responded to paclitaxel].
abstract: A 60-year-old man was admitted to our hospital complaining of back pain and bloody sputum. Chest CT scan showed characteristic multiple small nodules with central dense opacity and surrounding faint opacity, suggesting lesions with hemorrhage. Bone scintigram and MRI revealed multiple osteolytic lesions in pelvis and lumbar spine. Biopsy of the bone lesion established a diagnosis of angiosarcoma. Chemotherapy with paclitaxel and palliative radiotherapy for the bone were initiated. Pulmonary metastases dramatically diminished after 4 courses of paclitaxel treatment. After eight weeks, the tumor recurred. Salvage chemotherapy of weekly administration of docetaxel yielded limited effects. The patient died of cancer one year after treatment initiation.
authors: Dept. of Respirology, Graduate School of Medicine, Chiba University.
authors: Yuji
authors: Y
authors: Tada
authors: Yuichi
authors: Y
authors: Takiguchi
authors: Jiro
authors: J
authors: Terada
authors: Takako
authors: T
authors: Yoshida
authors: Aya
authors: A
authors: Shinozaki
authors: Seiichiro
authors: S
authors: Sakao
authors: Yasunori
authors: Y
authors: Kasahara
authors: Katsushi
authors: K
authors: Kurosu
authors: Nobuhiro
authors: N
authors: Tanabe
authors: Koichiro
authors: K
authors: Tatsumi
authors: Kenzo
authors: K
authors: Hiroshima
authors: Takayuki
authors: T
authors: Kuriyama
mesh_terms: D000972:Antineoplastic Agents, Phytogenic / Q000627:therapeutic use*; D001859:Bone Neoplasms / Q000188:drug therapy* / Q000473:pathology; D006394:Hemangiosarcoma / Q000188:drug therapy* / Q000473:pathology; D006801:Humans; D008175:Lung Neoplasms / Q000556:secondary*; D008297:Male; D008875:Middle Aged; D017239:Paclitaxel / Q000627:therapeutic use*; D010384:Pelvic Bones; D016879:Salvage Therapy
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D017239:Paclitaxel