title: PGSTE-WATERGATE: an STE-based PGSE NMR sequence with excellent solvent suppression.
abstract: A new stimulated-echo based pulsed gradient spin-echo NMR diffusion sequence incorporating WATERGATE solvent suppression, PGSTE-WATERGATE, is presented. The sequence provides superb solvent suppression without any phase distortions. The sequence is simple to set up and particularly suited to measuring diffusion coefficients in aqueous solution such as is commonly required in pharmaceutical and combinatorial applications. The utility of the sequence is demonstrated on samples containing lysozyme and sucrose. Importantly, the high degree of phase-distortion suppression allows more complicated selective pi pulses to be used to enhance the selectivity of solvent suppression.
authors: Nanoscale Organisation and Dynamics Group, University of Western Sydney, College of Health and Science, Penrith South DC, NSW 1797, Australia.
authors: Gang
authors: G
authors: Zheng
authors: Timothy
authors: T
authors: Stait-Gardner
authors: P G
authors: PG
authors: Anil Kumar
authors: Allan M
authors: AM
authors: Torres
authors: William S
authors: WS
authors: Price
mesh_terms: D000465:Algorithms; D016477:Artifacts; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D012815:Signal Processing, Computer-Assisted; D012997:Solvents / Q000737:chemistry*; D014867:Water / Q000737:chemistry*
chemical_list: D012997:Solvents; D014867:Water