Treatment of refractory seizures due to a benign mass present in the corpus callosum with an ion magnetic inductor: case report.
A 39-year-old female patient was having episodes of body stiffness that affected her motor abilities. A lipoma in the corpus callosum was identified by computed tomography. Her condition deteriorated rapidly, and seizures were refractory to any treatment. Seizure frequency and severity increased, incapacitating the patient completely. When seizure control was not achieved by any other treatment, the patient decided to undergo experimental therapy with the ion magnetic inductor. Treatment with the ion magnetic inductor notably reduced the seizure frequency and intensity. After treatment the patient was able to return to work and other normal activities. The long-term effects are not yet known, but there have been no adverse events to date. The patient is still undergoing ion magnetic inductor treatment daily in the same way other epileptic patients must continue with the use of antiepileptic drugs for life. There is evidence in the literature that other types of electromagnetic therapy, such as repetitive transcranial magnetic stimulation (rTMS), may be useful for treating refractory seizures. The potential advantage of the ion magnetic inductor over rTMS is that there is no need to locate precisely the epileptogenic focus, making the treatment procedure simpler and faster.
Mihajlovic-Madzarevic
Vera
V
Department of Research & Development, Global Research Pharma Canada, 34 Barcaly Court, Thornhill, Ontario L3T5T3, Canada. Vera@grpc.ca
Pappas
Panos
P
D000328:Adult; D061085:Agenesis of Corpus Callosum; D000927:Anticonvulsants / Q000627:therapeutic use; D003078:Colchicine / Q000008:administration & dosage / Q000031:analogs & derivatives / Q000627:therapeutic use; D003131:Combined Modality Therapy; D003337:Corpus Callosum / Q000473:pathology*; D003975:Diazepam / Q000008:administration & dosage / Q000627:therapeutic use; D004351:Drug Resistance; D004827:Epilepsy / Q000188:drug therapy / Q000209:etiology / Q000628:therapy*; D005260:Female; D006801:Humans; D007477:Ions; D008067:Lipoma / Q000150:complications*; D012074:Remission Induction; D013064:Speech Disorders / Q000209:etiology; D016750:Stiff-Person Syndrome / Q000209:etiology*; D015173:Supratentorial Neoplasms / Q000150:complications*; D050781:Transcranial Magnetic Stimulation / Q000379:methods*; D014635:Valproic Acid / Q000008:administration & dosage / Q000627:therapeutic use
D000927:Anticonvulsants; D007477:Ions; D014635:Valproic Acid; D003975:Diazepam; D003078:Colchicine; C004280:thiocolchicoside