title: Staging of early colorectal cancers: magnifying colonoscopy versus endoscopic ultrasonography for estimation of depth of invasion.
abstract: OBJECTIVE
  Preoperative estimation of depth of invasion in early colorectal cancers (CRCs) is essential for patient management. This study was conducted to compare the diagnostic accuracies of magnifying colonoscopy and endoscopic ultrasonography (EUS) for estimating the depth of invasion of early CRCs.
  
  
  METHODS
  A total of 438 early CRCs were removed endoscopically or surgically from July 1993 through March 1999 at our hospital. Before removal, 102 lesions were evaluated with both magnifying colonoscopy and EUS and were included in this analysis. The diagnostic accuracy of each method, referring to the histology of the resected specimens, was evaluated.
  
  
  RESULTS
  The overall diagnostic accuracies were 87% (89/102) for magnifying colonoscopy and 75% (76/102) for EUS (P = 0.0985). Subgroup analysis was also done for polypoid and non-polypoid lesions. For polypoid lesions, the overall diagnostic accuracies of magnifying colonoscopy and EUS were 88% (60/68) and 72% (49/68), (P = 0.0785), and for non-polypoid lesions, they were 85% (29/34) and 79% (27/34), (P = 0.7169).
  
  
  CONCLUSIONS
  Although, there is a substantial difference in the overall diagnostic accuracies, it is not statistically significant. Therefore, we conclude that magnifying colonoscopy is at least as accurate as EUS for preoperative staging of early CRCs.
authors: Department of Radiology, Dokkyo Medical University, 880 Kitakobayashi, Mibu, Shimotuga, Tochigi 321-0293, Japan. fukuangi@hotmail.com
authors: Kuang-I
authors: KI
authors: Fu
authors: Shigeharu
authors: S
authors: Kato
authors: Yasushi
authors: Y
authors: Sano
authors: Edward K
authors: EK
authors: Onuma
authors: Yutaka
authors: Y
authors: Saito
authors: Takahisa
authors: T
authors: Matsuda
authors: Ikuro
authors: I
authors: Koba
authors: Shigeaki
authors: S
authors: Yoshida
authors: Takahiro
authors: T
authors: Fujii
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016009:Chi-Square Distribution; D003113:Colonoscopy; D015179:Colorectal Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology* / Q000601:surgery; D019160:Endosonography; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D009367:Neoplasm Staging / Q000379:methods*