Effect of gold nanoparticle on the microscopic morphology of white blood cell.
BACKGROUND
In medicine, there is limited knowledge on the toxicity of nanoparticles. In medicine, there has been limited knowledge on the effect of nanoparticles on the white blood cell.


OBJECTIVE
To evaluate the effect of gold nanoparticle on the microscopic morphology of white blood cell.


METHODS
Chulalongkorn Univesity, Bangkok, Thailand.


METHODS
This study was performed as an experimental study. Mixture of gold nanoparticle solution and blood sample was prepared and analysed.


RESULTS
This work revealed that after mixing the blood sample with gold nanoparticle solution, accumulation of gold nanoparticle in the white blood cell was observed.


CONCLUSIONS
The effect of gold nanoparticle on the white blood cell can be detected and this knowledge can be used in cytotoxic drug treatment.
Wiwanitkit
V
V
Department of Clinical Laboratory Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand. wviroj@yahoo.com
Sereemaspun
A
A
Rojanathanes
R
R
D048430:Cell Shape / Q000187:drug effects; D006046:Gold / Q000494:pharmacology*; D006801:Humans; D007962:Leukocytes / Q000166:cytology / Q000187:drug effects; D053768:Metal Nanoparticles
D006046:Gold