title: [Clinical analysis of therapeutic effects of sphincter-preserving operation and Miles operation for rectal cancer].
abstract: OBJECTIVE
  To investigate and compare therapeutic effects of sphincter-preserving operation and Miles operation for rectal cancer.
  
  
  METHODS
  A retrospective analysis was carried out in 572 cases of rectal cancer operations performed from January 1980 to December 2006.
  
  
  RESULTS
  Sphincter-preserving operation was carried out in 403 cases and Miles procedure in 169 cases. The follow-up rate was 76.2% (436/572) with a period of 0.5 - 25.0 years (median, 9.5 years). Local recurrence occurred in 6.3% (20/317) of sphincter-preserving operation and 7.6% (9/119) of Miles operation, the differences was not significant (chi2 = 1.3942, P > 0.05). Distal metastasis was found in 50 cases (15.7%) of sphincter-preserving operation and 19 cases (16.2%) of the Miles operation with no significant difference (chi2 = 0.6672, P > 0.05). There was no significant difference in five-year survival rate between the two groups, with 67.8% in sphincter-preserving operation and 67.2% in Miles operation.
  
  
  CONCLUSIONS
  Sphincter-preserving operations can improve the quality of life in rectal cancer although with the same five-year survival rate and recurrence rate as Miles operation. The operation for rectal cancer should be performed individually according to the location, the bionomics and the clinical stage.
authors: Department of General Surgery, Beijing Army General Hospital, Beijing 100700, China.
authors: Fu-yi
authors: FY
authors: Zuo
authors: Shi-yong
authors: SY
authors: Li
authors: Bo
authors: B
authors: Yu
authors: Zhen-jia
authors: ZJ
authors: Liang
authors: Shu-jun
authors: SJ
authors: Yuan
authors: Gang
authors: G
authors: Chen
authors: Guang
authors: G
authors: Chen
authors: Xue
authors: X
authors: Bai
authors: Xiao-jun
authors: XJ
authors: Wei
authors: En
authors: E
authors: Wu
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001003:Anal Canal; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D053208:Kaplan-Meier Estimate; D008297:Male; D008875:Middle Aged; D011788:Quality of Life; D012004:Rectal Neoplasms / Q000401:mortality / Q000601:surgery*; D012189:Retrospective Studies; D013514:Surgical Procedures, Operative / Q000379:methods*; D015996:Survival Rate; D016896:Treatment Outcome