Heterogeneity of hemolysin expression during neonatal Streptococcus agalactiae sepsis.
The beta-hemolysin of Streptococcus agalactiae is a major virulence factor; consequently, nonhemolytic strains rarely cause infections. We report on a case of neonatal sepsis caused by a strain displaying heterogeneous hemolysin expression. It was detected by the simultaneous isolation of hemolytic and nonhemolytic colonies from cultures of the infant's blood.
Sigge
Anja
A
Institute of Medical Microbiology and Hygiene, Robert Koch Str. 8, Ulm D-89081, Germany.
Schmid
Manuel
M
Mauerer
Stefanie
S
Spellerberg
Barbara
B
D018528:ATP-Binding Cassette Transporters / Q000235:genetics; D000942:Antigens, Bacterial / Q000032:analysis; D001426:Bacterial Proteins / Q000032:analysis / Q000235:genetics / Q000502:physiology; D015373:Bacterial Typing Techniques; D004251:DNA Transposable Elements; D004269:DNA, Bacterial; D005838:Genotype; D006460:Hemolysin Proteins / Q000096:biosynthesis* / Q000235:genetics; D006461:Hemolysis / Q000235:genetics / Q000502:physiology*; D006801:Humans; D007231:Infant, Newborn; D008565:Membrane Proteins / Q000032:analysis; D016133:Polymerase Chain Reaction; D018805:Sepsis / Q000382:microbiology*; D012703:Serotyping; D013290:Streptococcal Infections / Q000382:microbiology*; D013292:Streptococcus agalactiae / Q000302:isolation & purification* / Q000502:physiology*
D018528:ATP-Binding Cassette Transporters; D000942:Antigens, Bacterial; D001426:Bacterial Proteins; D004251:DNA Transposable Elements; D004269:DNA, Bacterial; D006460:Hemolysin Proteins; D008565:Membrane Proteins; C081277:Rib protein, Streptococcus agalactiae