Determination of the minimum inhibitory concentration of four medicaments used as intracanal medication.
The aim of this study was to determine the minimum inhibitory concentration (MIC) of iodoform, calcium hydroxide, IKI (iodine potassium iodine) and CFC (ciprofloxacin, Flagyl (metronidazole) and calcium hydroxide) required to kill S. aureus, Pseudomonas aeruginosa, Enterococcus faecalis and B. fragilis. In the experiment, medicaments were added to bacterial species into test tubes, in 10 different concentrations. The MIC was the lowest concentration of the drug at which bacterial growth could not be observed. In this investigation, CFC was the most effective medicament against all bacteria. All drugs were able to eliminate E. faecalis and B. fragilis, while IKI was not effective against S. aureus. IKI and calcium hydroxide were not able to eliminate P. aeruginosa as well.
Pallotta
Raul C
RC
Department of endodontics, University Cruzeiro do Sul, Sao Paulo, Brazil. raulcapp@terra.com.br
Ribeiro
Mariangela S
MS
de Lima Machado
Manoel E
ME
D001441:Bacteroides fragilis / Q000187:drug effects; D003786:Dental Pulp Cavity / Q000382:microbiology*; D013293:Enterococcus faecalis / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D011550:Pseudomonas aeruginosa / Q000187:drug effects; D012388:Root Canal Irrigants / Q000008:administration & dosage*; D013211:Staphylococcus aureus / Q000187:drug effects
D012388:Root Canal Irrigants