[Expression of CIC-5 in rat tooth germ development].
OBJECTIVE
To determine the expression and possible function of CIC-5 during the rat tooth germ development.


METHODS
Isolated total mRNA and protein from the rat tooth germs which were at different stages of development. RT-PCR and Western blot were used to investigate the mRNA and protein expression of the CIC-5 in the rat tooth germ.


RESULTS
The mRNA and protein of CIC-5 expressed in the late bell stage, but undetected inThe mRNA and protein of CIC-5 expressed in the late bell stage, but undetected in the early or middle bell stage.


CONCLUSIONS
These results showed the spatial temporal distribution of expression of CIC-5 during the different stages of the rat tooth germ development and suggested that it might contribute to the rat tooth germ development.
Hou
Jin
J
Department of Oral Biology, School of Stomatology, The Fourth Military Medical University, Xi'an, China.
Duan
Xiao-hong
XH
Si-Tu
Zhen-qiang
ZQ
D000565:Ameloblasts; D000818:Animals; D009805:Odontogenesis; D012333:RNA, Messenger; D051381:Rats; D014083:Tooth Germ
D012333:RNA, Messenger