Successful pregnancy following double-frozen embryo transfer in a patient with repeated implantation failure.
OBJECTIVE
To report a case of successful singleton pregnancy following a novel technique of sequential double transfer of two groups of frozen embryos at the same developmental stage (8-cell) at 5 and 7 days after the LH surge to a patient with seven previous failed assisted reproductive technology (ART) cycles.


METHODS
Case report.


METHODS
University of Toronto affiliated infertility clinic.


METHODS
A 27-year-old female with a three-year history of primary infertility.


METHODS
Double frozen embryo transfer of day-3 embryos two days apart in the luteal phase.


METHODS
Successful pregnancy.


RESULTS
Successful singleton pregnancy resulting in the delivery of healthy baby boy.


CONCLUSIONS
To the best of our knowledge, the patient is the first to be treated successfully with double frozen-embryo transfer.
Esfandiari
Navid
N
Toronto Centre for Advanced Reproductive Technology, Toronto, Canada. nesfand@excite.com
Coogan-Prewer
Joan
J
Gotlieb
Lynda
L
Claessens
E Anne
EA
Casper
Robert F
RF
D000328:Adult; D015925:Cryopreservation / Q000379:methods*; D046149:Embryo Culture Techniques / Q000379:methods*; D010064:Embryo Implantation; D004624:Embryo Transfer / Q000379:methods*; D005260:Female; D006801:Humans; D007247:Infertility, Female / Q000628:therapy*; D050498:Live Birth; D011247:Pregnancy; D016896:Treatment Outcome