title: [Relationship between extracapsular spread of cervical metastatic lymph node and cervical recurrence in oral cancer patients].
abstract: OBJECTIVE
  To investigate the relationship between extracapsular spread (ECS) of cervical metastatic lymph node and the recurrence in patients with oral squamous cell carcinoma (OSCC).
  
  
  METHODS
  The medical records of 74 OSCC patients with histologically confirmed cervical lymph node metastasis were reviewed. They were divided into 2 groups, ECS positive (ECS+) and ECS negative (ECS-). The treatment results were followed up. Statistical analysis, with chi-square test, and multiple logistic regression was conducted.
  
  
  RESULTS
  The overall recurrence rates for pN+/ECS- and pN+/ECS+ patients were 47.6% and 75.0%, respectively, and the cervical recurrence rates for pN+/ECS- and pN+/ECS+ patients were 9.5% and 46.9%, respectively (P < 0.001). Multivariate analysis showed that ECS was one of the independent prognosis factors for cervical recurrence.
  
  
  CONCLUSIONS
  Extracapsular spread significantly increased both overall and cervical recurrence rates, and ESC may be a prognosis factor for OSCC patients.
authors: Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology, Beijing 100081, China.
authors: Shi-Qi
authors: SQ
authors: Zou
authors: Chi
authors: C
authors: Mao
authors: Yan
authors: Y
authors: Gao
authors: Xin
authors: X
authors: Peng
authors: Xiu-Wen
authors: XW
authors: Luan
authors: Ying-Bin
authors: YB
authors: Yan
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002294:Carcinoma, Squamous Cell / Q000473:pathology*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D016015:Logistic Models; D008198:Lymph Nodes / Q000473:pathology*; D008207:Lymphatic Metastasis / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009062:Mouth Neoplasms / Q000473:pathology*; D009333:Neck / Q000473:pathology; D009364:Neoplasm Recurrence, Local; D011379:Prognosis; D012189:Retrospective Studies