Synthetic use of epoxy-sugar nucleosides.
Preparation of 1',2 '-, 3 ',4 '-, and 4 ',5 '-epoxy derivatives of nucleosides and their use for the stereoselective synthesis of 1'- and 4 '-branched analogues are described.
Tanaka
Hiromichi
H
School of Pharmaceutical Sciences, Showa University, Shinagawa-ku, Tokyo, Japan. hirotnk@pharm.showa-u.ac.jp
Kubota
Yutaka
Y
Takeda
Shingo
S
Haraguchi
Kazuhiro
K
D000225:Adenine / Q000737:chemistry; D017607:Aluminum Compounds / Q000737:chemistry; D019380:Anti-HIV Agents / Q000737:chemistry; D002241:Carbohydrates / Q000737:chemistry*; D004852:Epoxy Compounds / Q000737:chemistry*; D009705:Nucleosides / Q000737:chemistry*; D018119:Stavudine / Q000737:chemistry; D013237:Stereoisomerism; D013941:Thymine / Q000737:chemistry
D017607:Aluminum Compounds; D019380:Anti-HIV Agents; D002241:Carbohydrates; D004852:Epoxy Compounds; D009705:Nucleosides; D018119:Stavudine; D000225:Adenine; D013941:Thymine