QuantiFERON TB Gold: a new method for latent tuberculosis infection.
QuantiFERON-TB Gold obtained approval in 2003 by the Food and Drug Administration as a valid tool for the diagnosis of latent tuberculosis. In this report, we evaluated its potential use in the immunological diagnosis of Mycobacterium tuberculosis infections in different groups of subjects. Our data indicate that QuantiFERON-TB Gold is specific for identifying subjects who have come into contact with M. tuberculosis and its use alongside traditional diagnostic techniques may be an important instrument for controlling tuberculosis.
Bua
Alessandra
A
Department of Biomedical Sciences, University of Sassari, Italy. ale.b76@email.it
Molicotti
Paola
P
Delogu
Giovanni
G
Pirina
Piero
P
Mura
Maria Stella
MS
Madeddu
Giordano
G
Franca Saba
F
F
Maida
Ivana
I
Sechi
Leonardo A
LA
Zanetti
Stefania
S
D000328:Adult; D000368:Aged; D000942:Antigens, Bacterial; D001426:Bacterial Proteins; D001431:Bacteriological Techniques / Q000379:methods*; D001769:Blood / Q000378:metabolism; D005260:Female; D006801:Humans; D007371:Interferon-gamma / Q000032:analysis / Q000096:biosynthesis; D008297:Male; D008875:Middle Aged; D011933:Reagent Kits, Diagnostic; D012680:Sensitivity and Specificity; D014376:Tuberculosis / Q000097:blood / Q000175:diagnosis*
D000942:Antigens, Bacterial; D001426:Bacterial Proteins; C117940:CFP-10 protein, Mycobacterium tuberculosis; C525005:ESAT-6 antigen, Mycobacterium leprae; D011933:Reagent Kits, Diagnostic; D007371:Interferon-gamma