title: Transcription factor logic using chemical complementation.
abstract: Chemical complementation was used to make a transcription factor circuit capable of performing complex Boolean logic.
authors: Department of Chemistry, Columbia University, New York, NY 10027, USA.
authors: Jonathan E
authors: JE
authors: Bronson
authors: William W
authors: WW
authors: Mazur
authors: Virginia W
authors: VW
authors: Cornish
mesh_terms: D001665:Binding Sites; D004268:DNA-Binding Proteins / Q000737:chemistry / Q000235:genetics / Q000378:metabolism; D015195:Drug Design; D004353:Drug Evaluation, Preclinical / Q000379:methods*; D005690:Galactose / Q000378:metabolism; D005786:Gene Expression Regulation; D053263:Gene Regulatory Networks / Q000502:physiology; D017930:Genes, Reporter; D007763:Lac Operon; D008024:Ligands; D008128:Logic; D008954:Models, Biological; D011485:Protein Binding; D017434:Protein Structure, Tertiary; D012984:Software; D014157:Transcription Factors / Q000737:chemistry* / Q000235:genetics / Q000378:metabolism* / Q000502:physiology; D020798:Two-Hybrid System Techniques
chemical_list: D004268:DNA-Binding Proteins; D008024:Ligands; D014157:Transcription Factors; D005690:Galactose