[Assessing the risk of HDL cholesterol].
Low HDL cholesterol levels represent a significant cardiovascular risk factor. HDL not only has a central role in the reverse transport of cholesterol but, independently of this, presumably also has anti-oxidative, anti-inflammatory, antithrombotic and endothelium-regulating properties. The reasons for lowered HDL cholesterol levels are manifold (genetic inheritance, life style). Measures with an influence on life style can have a decisive impact on the HDL cholesterol level. Medication-based options are much less well established, and the clinical endpoints less well investigated than the corresponding options for LDL-lowering drug therapies. Among the drugs currently available, niacin has the most pronounced HDL-elevating effect.
Klose
Gerald
G
Klinikum Links der Weser gGmbH, Bremen. miriam.meyer@klinikum-bremen-ldw.de
D000924:Anticholesteremic Agents / Q000627:therapeutic use; D008076:Cholesterol, HDL / Q000097:blood*; D018752:Diet, Fat-Restricted; D006801:Humans; D006937:Hypercholesterolemia / Q000097:blood* / Q000235:genetics / Q000628:therapy; D008019:Life Style; D012307:Risk Factors; D016540:Smoking Cessation; D016138:Walking
D000924:Anticholesteremic Agents; D008076:Cholesterol, HDL