title: Effects of intestinal electrical stimulation on postprandial small-bowel motility and transit in dogs.
abstract: BACKGROUND
  Intestinal electrical stimulation (IES) with long pulses has been reported to inhibit motility as well as accelerate transit of continuous infusion. However, it is unknown whether there is a correlation between the IES-induced alterations in motility and transit and whether there is a difference in transit during IES between continuous infusion and bolus infusion.
  
  
  METHODS
  The study was performed in 2 postprandial sessions (control and stimulation) in dogs with 2 pairs of serosal electrodes and 2 intestinal cannulas. Intestinal motility and transit with and without IES were measured by manometry and phenol red, respectively.
  
  
  RESULTS
  IES significantly decreased intestinal motility and increased transit time. There was a significant correlation between motility index and transit during IES.
  
  
  CONCLUSIONS
  IES inhibits both intestinal bolus motility and transit. There is correlation between motility and transit during IES.
authors: University of Texas Medical Branch, Division of Gastroenterology, Route 0632, Room 221 Microbiology Bldg., 1108 The Strand, Galveston, TX 77555-0632, USA.
authors: Huibin
authors: H
authors: Qi
authors: Jiande D Z
authors: JD
authors: Chen
mesh_terms: D000818:Animals; D004285:Dogs; D004558:Electric Stimulation; D004567:Electrodes, Implanted; D005260:Female; D005769:Gastrointestinal Motility / Q000502:physiology*; D007421:Intestine, Small / Q000503:physiopathology*; D008365:Manometry; D019518:Postprandial Period / Q000502:physiology*