Childhood leukaemia and population movements in France, 1990-2003.
In a national study, we investigated the incidence of childhood leukaemia (CL) over a 14-year period in France in relation to several measures based on the proportion of individuals who changed address between the last two national censuses. A positive association was found with the proportion of migrants who came from a distant place. The further the migrants came, the higher was the incidence of leukaemia, particularly among children aged 0-4 years in 'isolated' communes at the time of diagnosis (RR=1.4, 95% CI: 1.1,1.8 in the highest category of migration distance). Although the role of the population density was less obvious, a more marked association was found above a certain threshold. No association with the proportion of commuters was observed.
Bellec
S
S
INSERM, U754, Hôpital Paul Brousse, F-94807 Villejuif, France. bellec@vjf.inserm.fr
Baccaïni
B
B
Goubin
A
A
Rudant
J
J
Ripert
M
M
Hémon
D
D
Clavel
J
J
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D015331:Cohort Studies; D005602:France / Q000453:epidemiology; D006801:Humans; D015994:Incidence; D007223:Infant; D007231:Infant, Newborn; D007938:Leukemia / Q000453:epidemiology*; D011156:Population Density; D011157:Population Dynamics / Q000706:statistics & numerical data*; D015996:Survival Rate