title: A biomechanical model for real-time simulation of PMMA injection with haptics.
abstract: We have developed a computationally efficient rheological model to simulate polymethylmethacrylate (PMMA) injection into cancellous bone during percutaneous vertebroplasty. The model employs the Hagen-Poiseuille law to predict pressure drop across a delivery cannula with viscoelastic changes of curing PMMA modeled via a time and shear-rate-dependent power law. The power law was derived based on dynamic rheological testing of curing PMMA samples. In conjunction with a branching-pipe geometrical model that is reconstructed from micro-computed tomography scans of cancellous bone for estimating pressure changes during PMMA flow in bone, the method provides a fast estimation of overall injection pressure, and, hence, the reaction force during manual PMMA injection.
authors: Department of Mechanical Engineering, Faculty of Engineering, National University of Singapore, 9 Engineering Drive 1, Singapore 117576, Singapore.
authors: Z
authors: Z
authors: Lian
authors: C-K
authors: CK
authors: Chui
authors: S-H
authors: SH
authors: Teoh
mesh_terms: D000465:Algorithms; D001696:Biomechanical Phenomena; D003198:Computer Simulation; D006801:Humans; D008954:Models, Biological; D009985:Orthopedics / Q000193:education / Q000379:methods; D019904:Polymethyl Methacrylate / Q000008:administration & dosage*; D015203:Reproducibility of Results; D012212:Rheology; D054854:Vertebroplasty / Q000193:education / Q000379:methods*
chemical_list: D019904:Polymethyl Methacrylate