title: The biologic significance of micrometastatic disease and sentinel lymph node technology on colorectal cancer.
abstract: The sentinel lymph node (SLN) technique has practical applications in multiple solid tumors including colorectal carcinoma. Identifying the SLN(s) provides better staging of the regional lymphatics beyond standard H&E analysis. This additional information assists in predicting biology and may be useful in guiding adjuvant therapy. We postulate the era of sentinel node has ushered in a new generation of node-negative patients; patients that have an exceptionally favorable outcome when compared to historic controls.
authors: Department of Surgical Oncology, John Wayne Cancer Institute at Saint John's Health Center, Santa Monica, California 90404, USA.
authors: Douglas
authors: D
authors: Iddings
authors: Anton
authors: A
authors: Bilchik
mesh_terms: D001695:Biology; D002277:Carcinoma / Q000556:secondary*; D003110:Colonic Neoplasms / Q000473:pathology*; D006801:Humans; D008207:Lymphatic Metastasis / Q000473:pathology*; D013677:Medical Laboratory Science; D020360:Neoadjuvant Therapy; D009367:Neoplasm Staging; D012004:Rectal Neoplasms / Q000473:pathology*; D021701:Sentinel Lymph Node Biopsy