Acute renal failure after initiation of tenofovir disoproxil fumarate.
Despite initial evidence suggesting a relatively benign safety profile, several subsequent case reports have detailed nephrotoxicity in patients using tenofovir disoproxil fumarate for the treatment of HIV. We report a case of rapid renal failure that developed into an HIV-naïve patient initiated on an antiretroviral regimen that included tenofovir.
Hynes
Peter
P
Department of Medicine, NYU School of Medicine, New York, New York 10016, USA.
Urbina
Antonio
A
McMeeking
Alexander
A
Barisoni
Laura
L
Rabenou
Rahmin
R
D058186:Acute Kidney Injury / Q000139:chemically induced*; D000225:Adenine / Q000009:adverse effects / Q000031:analogs & derivatives*; D019380:Anti-HIV Agents / Q000009:adverse effects*; D015658:HIV Infections / Q000188:drug therapy; D006801:Humans; D008297:Male; D008875:Middle Aged; D063065:Organophosphonates / Q000009:adverse effects*; D000068698:Tenofovir
D019380:Anti-HIV Agents; D063065:Organophosphonates; D000068698:Tenofovir; D000225:Adenine