Extremely low frequency electromagnetic fields prevent chemotherapy induced myelotoxicity.
Side effects of chemo-radiotherapy reduce the quality and also the survivability of patients. The consequent fatigue and infections, related to myelodepression, act to reduce the dose-intensity of the protocol. Late side effects of chemo-radiotherapy include secondary tumours, acute myeloid leukemias and cardiotoxicity. Side effects of chemotherapy are related to oxidative stress produced by the treatment. Oxidative stress also reduces the efficacy of the treatment. Antioxidative treatment with natural (dietetic) or chemical agents has been reported to reduce the toxicity of chemo-radiotherapy and improve the efficacy of treatment. We here report our experience with SEQEX, an electromedical device that generates Extremely Low Frequency ElectroMagnetic Fields (ELF-EMF) to produce endogenic cyclotronic ionic resonance, to reduce myelotoxicity consequent to ABVD protocol in patients with Hodgkin's lymphoma.
Rossi
Edoardo
E
Department of Haematology, University-Hospital San Martino, Genoa, Italy. edoardo.rossi@hsanmartino.it
Corsetti
Maria Teresa
MT
Sukkar
Samir
S
Poggi
Claudio
C
D000328:Adult; D000368:Aged; D000970:Antineoplastic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D001853:Bone Marrow / Q000187:drug effects* / Q000473:pathology*; D004305:Dose-Response Relationship, Drug; D004574:Electromagnetic Fields; D005260:Female; D016179:Granulocyte Colony-Stimulating Factor / Q000494:pharmacology; D006454:Hemoglobins / Q000378:metabolism; D006689:Hodgkin Disease / Q000188:drug therapy* / Q000276:immunology / Q000378:metabolism; D006801:Humans; D008297:Male; D008875:Middle Aged; D018384:Oxidative Stress / Q000187:drug effects
D000970:Antineoplastic Agents; D006454:Hemoglobins; D016179:Granulocyte Colony-Stimulating Factor