Intravesical botulinum toxin type A in chronic interstitial cystitis: results of a pilot study.
OBJECTIVE
To assess the efficacy of intravesical botulinum toxin type A (BTX-A) in interstitial cystitis (IC).


METHODS
Eleven patients with IC were injected with BTX-A. Primary outcome measures were: Bristol Female Lower Urinary Tract Symptom Score, Kings Health Questionnaire and 24-hour frequency-volume chart. They had urodynamics done before and six weeks after injection. Detrusor contractility was assessed using the modified PIP1 (projected isovolumetric detrusor pressure).
Ramsay
A K
AK
Department of Urology, Southern General Hospital, Glasgow. alisonramsay@doctors.org.uk
Small
D R
DR
Conn
I G
IG
D000283:Administration, Intravesical; D019274:Botulinum Toxins, Type A / Q000008:administration & dosage* / Q000627:therapeutic use; D018856:Cystitis, Interstitial / Q000188:drug therapy* / Q000503:physiopathology; D006801:Humans; D009465:Neuromuscular Agents / Q000008:administration & dosage* / Q000627:therapeutic use; D010865:Pilot Projects; D011446:Prospective Studies; D014563:Urodynamics
D009465:Neuromuscular Agents; D019274:Botulinum Toxins, Type A