Serial changes in white matter lesions in a neonate with incontinentia pigmenti.
METHODS
We report an infant who presented with clinical manifestations of incontinentia pigmenti (IP). Despite experiencing seizures in the early neonatal period, the patient had normal growth and development until recently. However, follow-up magnetic resonance imaging revealed sequential changes in white matter lesions.


CONCLUSIONS
The pathogenesis of neurological involvement in IP has not been clearly elucidated and appears to be associated with various mechanisms, including developmental, destructive, and vascular processes. We have attempted to explain the pathogenesis of IP through these changes.
Lee
J H
JH
Department of Pediatrics, College of Medicine, The Catholic University of Korea, Seoul, South Korea.
Im
S A
SA
Chun
J S
JS
D001930:Brain Injuries / Q000150:complications / Q000473:pathology*; D018450:Disease Progression; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007184:Incontinentia Pigmenti / Q000150:complications* / Q000473:pathology*; D007223:Infant; D008279:Magnetic Resonance Imaging / Q000379:methods; D009457:Neuroglia / Q000473:pathology*