[Combination of stereotactic lesion and multiple subpial transsection in treatment of bitemporal lobe epilepsy: report of 12 cases].
OBJECTIVE
To explore the effect of combination of stereotactic lesion and multiple subpial transsection (MST) in treatment of bitemporal lobe epilepsy (BTLE).


METHODS
Independent epileptogenic foci were found in bilateral temporal lobes by video-electroencephalogram, computed tomogrphy, magnetic resonance imaging, magnetic resonance spectroscopy, positron emission tomography-computed tomography, magnetoencephalography, neuropsychology and intraoperative electrocoticography, and depth EEG in 12 patients with intractable epilepsy. Then the BTLE patients were treated with stereotactic amygdalohippocampotomy (SAHT) and MST respectively according to the sites of the. epileptogenic foci: in the amygdalohippocampus complex or temporal neocortex. Followed-up was conducted for 6 - 32 months.


RESULTS
The curative effects of the 12 patients according to Engel's standard were grade I in 5 cases, grade II in 3 case, grade III in 3 cases, and grade IV in 1 case. No permanent complication was found.


CONCLUSIONS
Combination of SAHT and MST procedures is safe and effective in treatment of bitemporal lobe epilepsy.
Yang
Wei-Dong
WD
Department of Neurosurgery, General Hospital of Tianjin Medical University, Tianjin, China.
Yu
Qing
Q
Pu
Pei-Yu
PY
Zhang
Jian-Ning
JN
Yang
Shu-Yuan
SY
D000328:Adult; D000679:Amygdala / Q000473:pathology / Q000601:surgery*; D004833:Epilepsy, Temporal Lobe / Q000175:diagnosis / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006624:Hippocampus / Q000473:pathology / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D013238:Stereotaxic Techniques; D016896:Treatment Outcome