Headache in a patient with Klinefelter's syndrome and hyperostosis frontalis interna.
Hyperostosis frontalis interna (HFI) has been reported in older women, but reports in men are rare. We present a novel case of migraine headache in a gentleman with Klinefelter's syndrome and HFI, along with a discussion of possible pathophysiologic mechanisms underlying both the headache and the HFI.
Ramchandren
Sindhu
S
Department of Neurology, University of Michigan at Ann Arbor, 300 North Ingalls St., #3D06, Ann Arbor, MI 48109, USA. sindhur@med.umich.edu
Liebeskind
David S
DS
D000328:Adult; D000639:Amitriptyline / Q000627:therapeutic use; D018712:Analgesics, Non-Narcotic / Q000627:therapeutic use; D006801:Humans; D006957:Hyperostosis Frontalis Interna / Q000150:complications* / Q000473:pathology; D002546:Ischemic Attack, Transient / Q000150:complications; D007713:Klinefelter Syndrome / Q000150:complications*; D008279:Magnetic Resonance Imaging; D008297:Male; D008881:Migraine Disorders / Q000150:complications* / Q000517:prevention & control; D009765:Obesity / Q000150:complications; D020181:Sleep Apnea, Obstructive
D018712:Analgesics, Non-Narcotic; D000639:Amitriptyline