[Risk status of patients with peripheral arterial disease (PAD)].
The authors have analyzed clinical and laboratory risk factors of 168 patients with PAD and 82 control persons. Among the patients the prevalences of diabetes, coronary heart disease (CHD), and cerebrovascular disease (CVD) were 30.4%, 39.9%, and 6.5%, respectively. 7.1% of the patients had CHD and CVD. Among patients with PAD and control persons, the prevalences of hypertension and current smoking were 76.2% vs 46.3% and 49.4% vs 28%. HDL-cholesterol and ApoA1 levels were significantly lower, while the triglycerides, fibrinogen, hsCRP, homocysteine, creatinine, uric acid levels, and white blood cell count as well as plasma viscosity were significantly higher in the patient group compared with the values of control persons. Among the PAD patients the diabetics and the smokers had further unfavourable significant differencies in the laboratory findings compared with the data of non-diabetics and non-smokers. Correlations were detected between the hsCRP level and the white blood cell count, the plasma viscosity and the fibrinogen level, respectively. Examining 16 selected risk factors the average risk factor count of the patients was 7.79. 118 patients had lipid-lowering, and 142 patients had antithrombotic therapy. Our results emphasize the necessity of the secondary prevention among PAD patients.
Jassó
István
I
Fovárosi Onkormányzat Egyesített Szent István és Szent László Kórház IV Belgyógyászati Osztály, Budapest, Hungary. jasso.istvan@t-online.hu
Landi
Anna
A
Dinya
Elek
E
D000368:Aged; D001157:Arterial Occlusive Diseases / Q000097:blood* / Q000209:etiology* / Q000517:prevention & control; D015415:Biomarkers / Q000097:blood; D001809:Blood Viscosity; D016022:Case-Control Studies; D002561:Cerebrovascular Disorders / Q000150:complications; D003327:Coronary Disease / Q000150:complications; D048909:Diabetes Complications / Q000097:blood; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications; D008297:Male; D008875:Middle Aged; D016491:Peripheral Vascular Diseases / Q000097:blood* / Q000209:etiology* / Q000517:prevention & control; D015995:Prevalence; D012307:Risk Factors; D012907:Smoking / Q000009:adverse effects
D015415:Biomarkers