title: Ectopic recurrence of dysplastic gangliocytoma of the cerebellum (Lhermitte-Duclos disease): a case report.
abstract: Lhermitte-Duclos disease is a rare clinical entity characterized by slow deformation of the cerebellar lesion. A 53-year-old woman presented with Lherimitte-Duclos disease manifesting as ataxic gait, occipital headache, and loss of consciousness. Magnetic resonance imaging demonstrated striated and laminar pattern lesions in the right cerebellar hemisphere and vermis. She underwent subtotal removal of the vermis compressing the brainstem, but the cerebellar hemisphere appeared normal and was preserved. Histological findings were consistent with Lherimitte-Duclos disease. Two years later, magnetic resonance imaging revealed enlargement of the right hemispheric lesion. Intraoperative appearance of the hemisphere demonstrated marked enlargement of the folia. Subtotal removal was performed. Histological examination showed no malignant findings. Lhermitte-Duclos disease may recur, and should be carefully followed up as a low-grade neoplasm, not as a hamartomatous disorder.
authors: Department of Neurosurgery, Aomori Prefectural Central Hospital, 2-1-1 Higashitsukurimichi, Aomori, Aomori, 030-8553, Japan. tomoo49@nsg.med.tohoku.ac.jp
authors: Tomoo
authors: T
authors: Inoue
authors: Shinjitsu
authors: S
authors: Nishimura
authors: Nakamasa
authors: N
authors: Hayashi
authors: Yoshihiro
authors: Y
authors: Numagami
authors: Mitsuomi
authors: M
authors: Kaimori
authors: Michiharu
authors: M
authors: Nishijima
mesh_terms: D001927:Brain Diseases / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D005260:Female; D006223:Hamartoma Syndrome, Multiple / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D006801:Humans; D007150:Immunohistochemistry; D008279:Magnetic Resonance Imaging; D008875:Middle Aged