Sensitivity of an Acinetobacter baylyi mpl mutant to DNA damage.
A mutant derived from Acinetobacter baylyi ADP1 was isolated from a screen for genes involved in the response to DNA damage. This derivative has an insertion in the mpl gene which encodes a peptidoglycan-recycling protein. We demonstrate that the insertion renders cells sensitive to mitomycin C and to UV.
Chakravorty
Adityarup
A
Department of Biology, Grinnell College, Grinnell, IA 50112, USA.
Klovstad
Martha
M
Peterson
Greg
G
Lindeman
Robin E
RE
Gregg-Jolly
Leslie A
LA
D000150:Acinetobacter / Q000187:drug effects / Q000235:genetics* / Q000528:radiation effects; D004249:DNA Damage; D008666:Metalloendopeptidases / Q000235:genetics*; D016685:Mitomycin / Q000633:toxicity; D009154:Mutation / Q000235:genetics*; D014466:Ultraviolet Rays
D016685:Mitomycin; D008666:Metalloendopeptidases