title: High prevalence of sleep disorders at the time of CKD diagnosis.
abstract: OBJECTIVE
  Sleep disorders are very common in adult and children on maintenance hemodialysis and are not cured by renal transplantation.
  
  
  METHODS
  Studies in our laboratory of patients with a mean plasma creatinine concentration of 2 mg/dL, studied within 2 months of chronic kidney disease (CKD) diagnosis, have detected a high prevalence of sleep disorders that could not be explained by using the factors prevalent in hemodialysis patients.
  
  
  METHODS
  To understand if the intrusiveness of the disease is a cause for the high prevalence of sleep disorders in early CKD, we have assessed, by means of a questionnaire, sleep disorders within 1 month from the diagnosis of renal dysfunction.
  
  
  RESULTS
  A total of 100 CKD patients with a mean estimated creatinine clearance of 59.1 +/- 26.7 mL/min were studied. The prevalence of sleep disorders was 89%.
  
  
  CONCLUSIONS
  We believe this high prevalence might represent the effects of disease's intrusiveness and difficulty in coping with the disease.
authors: Laboratory for Psychological Support, Dialysis Centre Neoren, Montesarchio, Italy. bluetoblue@libero.it
authors: Rosa Maria
authors: RM
authors: De Santo
authors: Concetta Maria
authors: CM
authors: Cesare
authors: Marilù
authors: M
authors: Bartiromo
authors: Massimo
authors: M
authors: Cirillo
mesh_terms: D000328:Adult; D002908:Chronic Disease; D005260:Female; D006801:Humans; D006993:Hypnotics and Sedatives / Q000627:therapeutic use; D007674:Kidney Diseases / Q000097:blood / Q000150:complications*; D007676:Kidney Failure, Chronic / Q000097:blood / Q000150:complications*; D008297:Male; D008875:Middle Aged; D010281:Parathyroid Hormone / Q000097:blood; D015995:Prevalence; D012893:Sleep Wake Disorders / Q000097:blood / Q000453:epidemiology* / Q000523:psychology; D011795:Surveys and Questionnaires; D014508:Urea / Q000097:blood
chemical_list: D006993:Hypnotics and Sedatives; D010281:Parathyroid Hormone; D014508:Urea