title: Prevalent and low-frequency null mutations in the filaggrin gene are associated with early-onset and persistent atopic eczema.
authors: Sara J
authors: SJ
authors: Brown
authors: Aileen
authors: A
authors: Sandilands
authors: Yiwei
authors: Y
authors: Zhao
authors: Haihui
authors: H
authors: Liao
authors: Caroline L
authors: CL
authors: Relton
authors: Simon J
authors: SJ
authors: Meggitt
authors: Richard C
authors: RC
authors: Trembath
authors: Jonathan N W N
authors: JN
authors: Barker
authors: Nick J
authors: NJ
authors: Reynolds
authors: Heather J
authors: HJ
authors: Cordell
authors: W H Irwin
authors: WH
authors: McLean
mesh_terms: D000483:Alleles; D004252:DNA Mutational Analysis; D003876:Dermatitis, Atopic / Q000235:genetics*; D000091344:Filaggrin Proteins; D005786:Gene Expression Regulation; D020022:Genetic Predisposition to Disease; D005838:Genotype; D006239:Haplotypes; D006801:Humans; D007381:Intermediate Filament Proteins / Q000235:genetics*; D015233:Models, Statistical; D009154:Mutation; D016017:Odds Ratio; D010641:Phenotype
chemical_list: C000717249:FLG protein, human; D000091344:Filaggrin Proteins; D007381:Intermediate Filament Proteins