[Are beta blockers no longer the medicines of choice for the treatment of hypertension?].
Intervention studies indicate that beta blockers as well as diuretics have unfavourable effects on lipid metabolism and lead to new onsets of diabetes mellitus more frequently than ACE inhibitors, AT1 antagonists and calcium antagonists. Moreover, a meta-analysis showed an elevated risk for strokes in hypertensive patients treated with beta blockers. Until the conclusion of other controlled studies, beta blockers will nevertheless retain their important role in the treatment of hypertensive patients with coronary heart disease or heart failure. They should continue to be one of the preferred antihypertensives.
Rahn
K H
KH
Medizinische Klinik und Poliklinik D, Universitätsklinikum Münster. rahn@uni-muenster.de
D000319:Adrenergic beta-Antagonists / Q000009:adverse effects* / Q000627:therapeutic use; D000959:Antihypertensive Agents / Q000009:adverse effects* / Q000627:therapeutic use; D001794:Blood Pressure / Q000187:drug effects; D004232:Diuretics / Q000009:adverse effects / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D006333:Heart Failure / Q000188:drug therapy; D006801:Humans; D006973:Hypertension / Q000188:drug therapy*; D015201:Meta-Analysis as Topic; D020521:Stroke / Q000139:chemically induced*; D016896:Treatment Outcome
D000319:Adrenergic beta-Antagonists; D000959:Antihypertensive Agents; D004232:Diuretics