Substituent effects of the N,N-dimethyl- sulfamoyl group on the 1H and 13C NMR spectra of positional isomers of quinolines.
The complete 1H and 13C NMR spectral assignments of seven positional isomers of N,N-dimethylsulfamoylquinolines 2-8 and quinoline have been made using 1D and 2D NMR techniques, including COSY, HMQC and HMBC experiments. Deltadelta(H) and Deltadelta(C) substituent effects induced by the sulfamoyl group were determined. The sulfamoyl substituent affects proton and carbon chemical shifts both in the parent and in the fused (pyridine or benzene) ring.
Maślankiewicz
Andrzej
A
Department of Organic Chemistry, Medical University of Silesia, Jagiellońska 4, 41-200 Sosnowiec, Poland. maslankiewicz@slam.katowice.pl
Maślankiewicz
Maria J
MJ
Marciniec
Krzysztof
K
D007536:Isomerism; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D011804:Quinolines / Q000138:chemical synthesis / Q000737:chemistry*; D013449:Sulfonamides / Q000138:chemical synthesis / Q000737:chemistry*
D011804:Quinolines; D013449:Sulfonamides