title: The structure of melon necrotic spot virus determined at 2.8 A resolution.
abstract: The structure of melon necrotic spot virus (MNSV) was determined at 2.8 A resolution. Although MNSV is classified into the genus Carmovirus of the family Tombusviridae, the three-dimensional structure of MNSV showed a higher degree of similarity to tomato bushy stunt virus (TBSV), which belongs to the genus Tombusvirus, than to carnation mottle virus (CMtV), turnip crinkle virus (TCV) or cowpea mottle virus (CPMtV) from the genus Carmovirus. Thus, the classification of the family Tombusviridae at the genus level conflicts with the patterns of similarity among coat-protein structures. MNSV is one of the viruses belonging to the genera Tombusvirus or Carmovirus that are naturally transmitted in the soil by zoospores of fungal vectors. The X-ray structure of MNSV provides us with a representative structure of viruses transmitted by fungi.
authors: Institute for Protein Research, Osaka University, 3-2 Yamada-oka, Suita, Osaka 565-0871, Japan.
authors: Yasunobu
authors: Y
authors: Wada
authors: Hideaki
authors: H
authors: Tanaka
authors: Eiki
authors: E
authors: Yamashita
authors: Chikako
authors: C
authors: Kubo
authors: Tamaki
authors: T
authors: Ichiki-Uehara
authors: Eiko
authors: E
authors: Nakazono-Nagaoka
authors: Toshihiro
authors: T
authors: Omura
authors: Tomitake
authors: T
authors: Tsukihara
mesh_terms: D036022:Capsid Proteins / Q000737:chemistry*; D019184:Carmovirus / Q000145:classification / Q000235:genetics / Q000648:ultrastructure*; D018360:Crystallography, X-Ray / Q000379:methods; D028464:Cucurbita / Q000821:virology*; D016679:Genome, Viral; D008958:Models, Molecular; D010935:Plant Diseases / Q000821:virology; D011487:Protein Conformation; D012680:Sensitivity and Specificity
chemical_list: D036022:Capsid Proteins