title: A case of Wegener's granulomatosis associated with progressive dysphagia owing to esophageal involvement.
abstract: A 52-year-old woman was admitted to our hospital with progressive dysphagia. Upper gastrointestinal endoscopy revealed esophageal stenosis and computed tomographic scan revealed symmetrical wall thickness of the thoracic esophagus. Biopsies findings from a lesion were unremarkable. However, a definitive diagnosis of Wegener's granulomatosis was based on positive anti-neutrophil cytoplasmic antibodies directed against proteinase 3 and otorhinolaryngological manifestations. Esophageal complications are rarely reported in Wegener's granulomatosis; however, clinicians should be aware of the possibility of esophageal involvement.
authors: Department of Internal Medicine, Osaka City Juso Hospital, 2-12-27 Nonaka-kita, Yodogawa-ku, Osaka, 532-0034, Japan. toshimasa1@excite.co.jp
authors: Toshimasa
authors: T
authors: Yamaguchi
authors: Katsunobu
authors: K
authors: Yoshioka
authors: Mami
authors: M
authors: Ueda
authors: Takashi
authors: T
authors: Morikawa
authors: Keiko
authors: K
authors: Yamagami
authors: Yoshio
authors: Y
authors: Konishi
authors: Toshihiko
authors: T
authors: Sato
authors: Yasuko
authors: Y
authors: Kawasaki
authors: Masahito
authors: M
authors: Imanishi
mesh_terms: D019268:Antibodies, Antineutrophil Cytoplasmic / Q000276:immunology; D003520:Cyclophosphamide / Q000627:therapeutic use; D003680:Deglutition Disorders / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D018450:Disease Progression; D004940:Esophageal Stenosis / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D004947:Esophagus / Q000473:pathology*; D005260:Female; D014890:Granulomatosis with Polyangiitis / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008875:Middle Aged; D053146:Myeloblastin / Q000276:immunology; D011239:Prednisolone / Q000627:therapeutic use; D016896:Treatment Outcome
chemical_list: D019268:Antibodies, Antineutrophil Cytoplasmic; D007166:Immunosuppressive Agents; D003520:Cyclophosphamide; D011239:Prednisolone; D053146:Myeloblastin