title: Colloidal silver fabrication using the spark discharge system and its antimicrobial effect on Staphylococcus aureus.
abstract: Nanoscale techniques for silver production may assist the resurgence of the medical use of silver, especially given that pathogens are showing increasing resistance to antibiotics. Traditional chemical synthesis methods for colloidal silver (CS) may lead to the presence of toxic chemical species or chemical residues, which may inhibit the effectiveness of CS as an antibacterial agent. To counter these problems a spark discharge system (SDS) was used to fabricate a suspension of colloidal silver in deionized water with no added chemical surfactants. SDS-CS contains both metallic silver nanoparticles (Ag(0)) and ionic silver forms (Ag(+)). The antimicrobial affect of SDS-CS on Staphylococcus aureus was studied. The results show that CS solutions with an ionic silver concentration of 30 ppm or higher are strong enough to destroy S. aureus. In addition, it was found that a solution's antimicrobial potency is directly related to its level of silver ion concentration.
authors: Graduate Institute of Mechanical and Electrical Engineering, National Taipei University of Technology, Da-An District, Taipei 106, Taiwan. s3408508@ntut.edu.tw
authors: Der-Chi
authors: DC
authors: Tien
authors: Kuo-Hsiung
authors: KH
authors: Tseng
authors: Chih-Yu
authors: CY
authors: Liao
authors: Tsing-Tshih
authors: TT
authors: Tsung
mesh_terms: D000890:Anti-Infective Agents / Q000008:administration & dosage* / Q000138:chemical synthesis*; D002470:Cell Survival / Q000187:drug effects; D003102:Colloids / Q000008:administration & dosage / Q000138:chemical synthesis; D004563:Electrochemistry / Q000379:methods; D006358:Hot Temperature; D049329:Nanostructures / Q000008:administration & dosage* / Q000737:chemistry / Q000648:ultrastructure; D010316:Particle Size; D012834:Silver / Q000008:administration & dosage* / Q000737:chemistry*; D013211:Staphylococcus aureus / Q000166:cytology* / Q000187:drug effects*
chemical_list: D000890:Anti-Infective Agents; D003102:Colloids; D012834:Silver