Thrombotic microangiopathy (TTP and HUS): advances in differentiation and diagnosis.
Detection of the proteolytic enzyme ADAMTS-13 may be used to differentiate between the forms of thrombotic microangiopathy (TMA), thrombotic thrombocytopenic purpura (TTP) and hemolytic-uremic syndrome (HUS).
Schneider
Margaret
M
William Beaumont Hospital, 35212 Banbury Court, Livonia, MI 48152, USA. mschneider@twmi.rr.com
D051722:ADAM Proteins / Q000097:blood*; D000071120:ADAMTS13 Protein; D019411:Clinical Laboratory Techniques; D003937:Diagnosis, Differential; D005260:Female; D006463:Hemolytic-Uremic Syndrome / Q000175:diagnosis*; D006801:Humans; D008297:Male; D011697:Purpura, Thrombotic Thrombocytopenic / Q000175:diagnosis*
D051722:ADAM Proteins; D000071120:ADAMTS13 Protein; C099604:ADAMTS13 protein, human