Huge renal cyst with parietal renal cell carcinoma, osseous metaplasia and a papillary adenoma: a case report with unique clinicopathological features and literature review.
The unique clinicopathological features of a giant solitary renal cyst with a parietal clear cell carcinoma in contiguity with a focus of osseous metaplasia and a papillary adenoma are reported. Ultrasonography and computed tomography showed a single cyst with a focal wall irregularity. During surgery, a frozen section revealed the presence of a renal cell carcinoma of clear cell type, so a nephrectomy was performed. After extensive pathological sampling of the cyst's wall, a focus of osseous metaplasia in contiguity with the main tumour and a microscopic papillary adenoma were found. Diagnostic implications for the present case are discussed within a pertinent literature review.
Puppa
Giacomo
G
Division of Pathology, CRO-Istituto Nazionale Tumori, Aviano, Italy. gpuppa@yahoo.com
Gervasio
Andrea
A
Yorukoglu
Kutsal
K
Colombari
Romano
R
De Marchi
Francesco
F
Canzonieri
Vincenzo
V
D000236:Adenoma / Q000378:metabolism / Q000473:pathology*; D002292:Carcinoma, Renal Cell / Q000378:metabolism / Q000473:pathology*; D006801:Humans; D007150:Immunohistochemistry; D053552:Keratin-7 / Q000032:analysis; D007668:Kidney / Q000737:chemistry / Q000000981:diagnostic imaging; D052177:Kidney Diseases, Cystic / Q000378:metabolism / Q000473:pathology*; D007680:Kidney Neoplasms / Q000378:metabolism / Q000473:pathology*; D008297:Male; D008679:Metaplasia; D008875:Middle Aged; D015260:Neprilysin / Q000032:analysis; D011859:Radiography; D014463:Ultrasonography
D053552:Keratin-7; D015260:Neprilysin