A case of tanycytic ependymoma arising from the cerebral hemisphere.
We report a rare case of tanycytic ependymoma arising from the cerebral hemisphere. A 59-year-old man was admitted to our hospital because of the incidental detection by MRI of a tumor lesion in the right temporooccipital paratrigonal region. The mass showed low-to iso-intensity on T1-weighted images and high intensity on T2/proton-weighted images. Partial resection was performed using a transsulcal approach to avoid compromising the visual field. Most of the tumor cells showed elongated spindle shapes arranged in dense fascicles. A few true ependymal rosettes and perivascular pseudorosettes were visible. The tumor cells were positive for GFAP, S-100, and vimentin, but negative for synaptophysin, EMA, and keratin. The MIB-1 labeling index was approximately 1%. Ultrastructurally, the tumor cells had ependymal cell features, such as microvilli and cilia. From these findings, a pathological diagnosis of tanycytic ependymoma was made.
Ito
Tamio
T
Department of Neurosurgery, Nakamura Memorial Hospital, South 1, West 14, Sapporo, 060-8570, Japan. titoh@med.nmh.or.jp
Ozaki
Yoshimaru
Y
Nakamura
Hirohiko
H
Tanaka
Shinya
S
Nagashima
Kazuo
K
D014408:Biomarkers, Tumor; D001932:Brain Neoplasms / Q000473:pathology* / Q000601:surgery / Q000648:ultrastructure; D049109:Cell Proliferation; D020785:Central Nervous System Vascular Malformations / Q000473:pathology; D002533:Cerebral Angiography; D004806:Ependymoma / Q000473:pathology* / Q000601:surgery / Q000648:ultrastructure; D006801:Humans; D007091:Image Processing, Computer-Assisted; D007150:Immunohistochemistry; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D013793:Thallium; D015899:Tomography, Emission-Computed, Single-Photon; D014794:Visual Fields
D014408:Biomarkers, Tumor; D013793:Thallium