title: Elevated body temperature exaggerates laryngeal chemoreflex apnea in decerebrate piglets.
abstract: We investigated the interaction between body temperature and the duration of the laryngeal chemoreflex (LCR) in decerebrate piglets. Elevating body temperature by approximately 2 degrees C prolongs the duration of the LCR and the length of apnea associated with the reflex. This thermal prolongation seems to arise within the nucleus of the solitary tract in the brainstem, and we believe the thermal effect is mediated by enhanced GABAergic neurotransmission.
authors: Dartmouth Medical School, Department of Physiology, USA.
authors: Luxi
authors: L
authors: Xia
authors: Tracey
authors: T
authors: Damon
authors: J C
authors: JC
authors: Leiter
authors: Donald
authors: D
authors: Bartlett
mesh_terms: D000818:Animals; D001049:Apnea / Q000503:physiopathology*; D002628:Chemoreceptor Cells / Q000502:physiology; D003655:Decerebrate State; D004195:Disease Models, Animal; D005334:Fever / Q000503:physiopathology*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007830:Larynx / Q000503:physiopathology*; D012018:Reflex / Q000502:physiology*; D013398:Sudden Infant Death / Q000453:epidemiology; D013552:Swine