Discrimination of herpes simplex virus type 2 strains by nucleotide sequence variations.
We determined the polymorphous 400-bp regions in UL53, US1, and US4 for the discrimination of herpes simplex virus type 2 (HSV-2) strains. Thirty-six HSV-2 clinical strains could be differentiated into 35 groups using these three regions and into 36 groups by additional analysis of three noncoding regions previously reported as polymorphous.
Kaneko
Hisatoshi
H
Department of Microbiology, Fukushima Medical University School of Medicine, Fukushima 960-1295, Japan.
Kawana
Takashi
T
Ishioka
Ken
K
Fukushima
Eiko
E
Suzutani
Tatsuo
T
D017931:DNA Primers; D004279:DNA, Viral / Q000235:genetics*; D006023:Glycoproteins / Q000235:genetics; D006561:Herpes Simplex / Q000821:virology; D018258:Herpesvirus 2, Human / Q000145:classification* / Q000235:genetics* / Q000302:isolation & purification; D006801:Humans; D017874:Immediate-Early Proteins / Q000235:genetics; D008969:Molecular Sequence Data; D010802:Phylogeny; D016133:Polymerase Chain Reaction; D011110:Polymorphism, Genetic; D017422:Sequence Analysis, DNA; D014764:Viral Proteins / Q000235:genetics
D017931:DNA Primers; D004279:DNA, Viral; D006023:Glycoproteins; D017874:Immediate-Early Proteins; C527355:UL53 protein, human herpesvirus 2; C527356:US1 protein, human herpesvirus 2; C527357:US4 protein, human herpesvirus 2; D014764:Viral Proteins