title: Relationship of cytopathology and cervical infection to outcome of in-vitro fertilization and embryo transfer.
abstract: OBJECTIVE
  To determine whether a relationship exists between in-vitro fertilization and embryo transfer (IVF-ET) outcome and cervical infection or presence of human papillomavirus (HPV).
  
  
  METHODS
  Cervical scrapes, digital colposcopies, and cervical biopsies were performed in 1044 Chinese women undergoing IVF for tubal infertility or, in their partners, abnormal semen. The pregnant (n=415) and nonpregnant (n=629) groups differed neither in clinical signs of cervical inflammation nor in rate of HPV detection.
  
  
  RESULTS
  There were no associations between IVF-ET outcome and infection rate, degree of cytopathologic abnormality, detection of HPV, or results of digital colposcopy and cervical biopsy. Cytologic results did not correlate with any of the clinical parameters of IVF-ET.
  
  
  CONCLUSIONS
  No association was found between IVF-ET outcome and cervical infection, cytopathologic result, HPV detection, or result from the colposcopy or biopsy. Extensive testing and treatment for cervical infection do not appear necessary in IVF-ET candidates.
authors: Reproductive Medical Center, Peking University Third Hospital, Beijing, China. wangying02114@bjmu.edu.cn
authors: Ying
authors: Y
authors: Wang
authors: Changjuan
authors: C
authors: Wang
authors: Jie
authors: J
authors: Qiao
authors: Lina
authors: L
authors: Wang
authors: Siqun
authors: S
authors: Liang
mesh_terms: D000328:Adult; D001707:Biopsy, Needle; D002584:Cervix Uteri / Q000473:pathology* / Q000821:virology; D002681:China; D003127:Colposcopy; D004624:Embryo Transfer; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D030361:Papillomavirus Infections / Q000150:complications*; D011247:Pregnancy; D002577:Uterine Cervical Diseases / Q000473:pathology* / Q000821:virology*