Residents at high altitude show a lower glucose profile than sea-level residents throughout 12-hour blood continuous monitoring.
It is known that residents at high altitude (HA) have a lower basal glycemia than residents at sea level (SL). However, whether such a difference is maintained throughout the full day remains unknown. We compared 12-h blood glucose profiles from 10 healthy males native residents at HA (3250 m) and 8 male residents at SL. Glucose profile at HA was lower throughout the glucose monitoring than that at SL (mean profile: 50.6 +/- 3.7 and 73.4 +/- 4.0 mg/dL, respectively; p < 0.001). Basal and postprandial insulin and triacylglycerol values were similar in both groups. In conclusion, HA natives resident have a lower blood glucose profile than SL residents throughout 12-h continuous monitoring.
Castillo
Oscar
O
Instituto Nacional de Biología Andina, Universidad Nacional Mayor de San Marcos, Lima, Peru. oscar.oculm@gmail.com
Woolcott
Orison O
OO
Gonzales
Elizabeth
E
Tello
Victoria
V
Tello
Lida
L
Villarreal
Carmen
C
Méndez
Nicolás
N
Damas
Lucy
L
Florentini
Edgar
E
D000064:Acclimatization / Q000502:physiology*; D000328:Adult; D000531:Altitude; D001786:Blood Glucose / Q000032:analysis*; D005951:Glucose Tolerance Test; D006801:Humans; D007328:Insulin / Q000097:blood*; D008297:Male; D008991:Monitoring, Physiologic; D009051:Mountaineering / Q000502:physiology*; D019518:Postprandial Period; D012016:Reference Values
D001786:Blood Glucose; D007328:Insulin