title: [Weight loss and night sweats with unexpected tumor localization].
abstract: A 52-year-old patient presented himself with weight loss and night sweats. Laboratory analyses revealed a high sedimentation rate, elevated immunoglobulines and anaemia with sludge phenomenon. Differential diagnoses included Multiple Myeloma and Lymphoma. Having a risk constellation for HIV infection and just having recovered from oral thrush also made this diagnosis possible. Urinary analysis and chest x-ray were normal; however, CT-scan detected renal cell cancer with pulmonary metastases. Renal cell cancer is heterogeneous in presentation, symptoms are unspecific, therefore they are often discovered late when they have already metastasized. Paraneoplastic syndromes, e.g. hypercalcaemia or hypertension are not infrequent in renal cell cancer.
authors: Medizinische Poliklinik, Onkologie, Universitätsspital Basel.
authors: C
authors: C
authors: Oberholzer
authors: M
authors: M
authors: Sawatzki
authors: C
authors: C
authors: Rothermundt
mesh_terms: D002292:Carcinoma, Renal Cell / Q000175:diagnosis / Q000556:secondary*; D003937:Diagnosis, Differential; D005221:Fatigue / Q000209:etiology*; D006801:Humans; D007668:Kidney / Q000473:pathology; D007680:Kidney Neoplasms / Q000175:diagnosis*; D008168:Lung / Q000473:pathology; D008175:Lung Neoplasms / Q000175:diagnosis / Q000556:secondary*; D008297:Male; D008875:Middle Aged; D013546:Sweating; D014057:Tomography, X-Ray Computed; D015431:Weight Loss