Estimated number of cases, regional distribution and survival of patients diagnosed with acute myeloid leukemia between 1996 and 2000 in Rio Grande do Sul, Brazil.
Rio Grande do Sul (RS), in South Brazil, with about 10 million inhabitants, is known for its agricultural activities and consequent increased human exposure to toxic agents. Patients with de novo acute myeloid leukemia (AML) were included based on information retrieved from all referral hospitals in RS between 1996 and 2000. A total of 532 patients were registered. Median age at diagnosis was 42 years. The estimated annual incidence was 1.11 cases/100,000 inhabitants/year. There was an estimated incidence of 0.5-1 case per 100,000 inhabitants up to the age of 45 years, and of 3.5 cases per 100,000 inhabitants aged 70 years and older, with no geographical clusters. The mean 5-year survival rate was 17% for all cases. There was an increased number of M3 cases, as already described for individuals of Latin-American and the mortality rate was similar to that described in the literature.
Capra
Marcelo
M
Division of Hematology and Bone Marrow Transplantation, Hospital de Clínicas de Porto Alegre, Programa de Pós-Graduação em Clínica medica da Universidade Federal do Rio Grande do Sul. marcelocapra@hotmail.com
Vilella
Líbia
L
Pereira
Waldir Veiga
WV
Coser
Virgínia Maria
VM
Fernandes
Mário Sérgio
MS
Schilling
Marco Antônio
MA
Almeida
Denise
D
Gross
Mauro
M
Leite
Márcia
M
Hellwig
Tânia
T
Natchigal
Gilca
G
Zelmanowicz
Alice
A
Paskulin
Giorgio
G
Neumann
Jorge
J
Silla
Lúcia
L
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001938:Brazil / Q000453:epidemiology; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D015994:Incidence; D007223:Infant; D007231:Infant, Newborn; D015470:Leukemia, Myeloid, Acute / Q000453:epidemiology* / Q000401:mortality; D008297:Male; D008875:Middle Aged; D013997:Time Factors