title: Infrared measurement of human skin temperature to predict the individual maximum safe radiant exposure (IMSRE).
abstract: OBJECTIVE
  Radiant exposure (RE) is a critical treatment parameter to be optimized for laser hair removal (LHR). An objective and quantitative method to assess the individual maximum safe radiant exposure (IMSRE) would help clinicians optimize LHR while at the same time providing the safest possible laser therapy.
  
  
  METHODS
  Pulsed photo-thermal radiometry (PPTR) measurements were on a total of 403 spots on 13 volunteers. The radiometric signal at 20 milliseconds after the diagnostic laser pulse was used to predict the IMSRE using a simple analytic relationship. Laser pulses (wavelength 755 nm, 3 milliseconds pulse, 50 milliseconds cryogen spray cooling, 30 milliseconds delay) with RE's below and above the predicted IMSRE (range: 10-100 J/cm(2)) were applied and resulting injuries quantified through blind scoring.
  
  
  RESULTS
  IMSRE can be predicted quite robustly with PPTR for the broad range of human skin photo-types (I-IV) considered in this study.
  
  
  CONCLUSIONS
  The method presented herein should be useful in helping clinicians optimize LHR on an individual patient basis, with the highest possible safety.
authors: Beckman Laser Institute and Medical Clinic, University of California-Irvine, 1002 Health Sciences Road East, Irvine, CA 92612, USA. wverkruy@uci.edu
authors: Wim
authors: W
authors: Verkruysse
authors: Wangcun
authors: W
authors: Jia
authors: Walfre
authors: W
authors: Franco
authors: Thomas E
authors: TE
authors: Milner
authors: J Stuart
authors: JS
authors: Nelson
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D053685:Laser Therapy; D008297:Male; D008875:Middle Aged; D011829:Radiation Dosage; D011874:Radiometry; D012449:Safety; D012867:Skin / Q000528:radiation effects*; D012880:Skin Pigmentation; D012881:Skin Temperature