Persistent hiccup associated with intrathecal morphine infusion pump therapy.
Intraspinal drug-delivery therapy has been increasingly used in patients with intractable nonmalignant pain syndromes during the past two decades. Morphine, the only FDA-approved opioid for intrathecal administration, has been the principle agent for such therapy. Although intrathecal morphine infusion can produce profound spinal analgesia, it may also cause some untoward side effects. We describe the first case of persistent hiccup caused by intrathecal morphine infusion therapy.
Ruan
Xiulu
X
Physicians' Pain Specialists of Alabama, Mobile, Alabama 36607, USA.
Couch
John Patrick
JP
Shah
Rinoo
R
Wang
Frank
F
Liu
Hai Nan
HN
D000368:Aged; D000701:Analgesics, Opioid / Q000008:administration & dosage / Q000009:adverse effects*; D002908:Chronic Disease; D005260:Female; D006606:Hiccup / Q000139:chemically induced*; D006801:Humans; D004091:Hydromorphone / Q000494:pharmacology* / Q000627:therapeutic use; D007260:Infusion Pumps; D007278:Injections, Spinal; D008159:Lumbar Vertebrae / Q000187:drug effects / Q000473:pathology; D009020:Morphine / Q000008:administration & dosage / Q000009:adverse effects* / Q000494:pharmacology; D012307:Risk Factors; D013997:Time Factors
D000701:Analgesics, Opioid; D009020:Morphine; D004091:Hydromorphone