title: Staged repair of massive incisional hernias with loss of abdominal domain: a novel approach.
abstract: BACKGROUND
  The management of massive ventral hernias with loss of intra-abdominal domain is a challenging surgical dilemma. We report a novel approach for repairing these extremely complicated hernias.
  
  
  METHODS
  We retrospectively reviewed our experience with the staged resection of Gore Tex Dual mesh (WL Gore and Associates, Flagstaff, AZ) in the setting of massive abdominal wall defects. The initial stage involves reduction of the hernia and placement of a large sheet of Gore Tex Dual mesh secured to the fascial edges. Subsequent stages involve serial excision of the mesh until the fascia can be approximated in the midline without tension. Finally, the mesh is excised, and the fascia is reapproximated with component separation and AlloDerm (Lifecell Corporation, Branchburg, NJ) underlay.
  
  
  RESULTS
  We have performed this procedure on 8 patients, with a mean age of 53 years (range 35-76). All patients had multiply recurrent ventral hernias with an average of 4.3 prior laparotomies (range 2-9). The fascial defect averaged 535 cm2 (300-884 cm2), and on average 6 serial operations were necessary to achieve fascial closure. The average length of stay was 36 days (range 9-90). One patient developed a postoperative wound infection requiring operative debridement, and 1 recurrence was identified during follow-up after an early wound complication.
  
  
  CONCLUSIONS
  Serial Gore-Tex excision to facilitate primary fascial closure with AlloDerm sublay is an effective treatment for massive, incisional hernias with loss of abdominal domain and avoids the risks associated with long-term prosthetic fascial closures.
authors: Department of General Surgery, Case Medical Center, University Hospitals, Cleveland, OH, USA.
authors: Jeremy
authors: J
authors: Lipman
authors: Daniel
authors: D
authors: Medalie
authors: Michael J
authors: MJ
authors: Rosen
mesh_terms: D034861:Abdominal Wall / Q000601:surgery*; D000328:Adult; D000368:Aged; D001672:Biocompatible Materials; D003094:Collagen; D005260:Female; D006555:Hernia, Ventral / Q000209:etiology / Q000601:surgery*; D006801:Humans; D007813:Laparotomy / Q000009:adverse effects; D008297:Male; D008875:Middle Aged; D019651:Plastic Surgery Procedures / Q000379:methods*; D012008:Recurrence; D012086:Reoperation / Q000009:adverse effects; D012189:Retrospective Studies; D013526:Surgical Mesh
chemical_list: C440568:Alloderm; D001672:Biocompatible Materials; D003094:Collagen