International Scientific Committee of Radionuclides in Nephrourology (ISCORN) consensus on renal transit time measurements.
This report is the conclusion of the international consensus committee on renal transit time (subcommittee of the International Scientific Committee of Radionuclides in Nephrourology) and provides recommendations on measurement, normal values, and analysis of clinical utility. Transit time is the time that a tracer remains within the kidney or within a part of the kidney (eg, parenchymal transit time). It can be obtained from a dynamic renogram and a vascular input acquired in standardized conditions by a deconvolution process. Alternatively to transit time measurement, simpler indices were proposed, such as time of maximum, normalized residual activity or renal output efficiency. Transit time has been mainly used in urinary obstruction, renal artery stenosis, or renovascular hypertension and renal transplant. Despite a large amount of published data on obstruction, only the value of normal transit is established. The value of delayed transit remains controversial, probably due to lack of a gold standard for obstruction. Transit time measurements are useful to diagnose renovascular hypertension, as are some of the simpler indices. The committee recommends further collaborative trials.
Durand
Emmanuel
E
Univ Paris-Sud, Department of Biophysics and Nuclear Medicine, Le Kremlin-Bicêtre, France. emmanuel.durand@u-psud.fr
Blaufox
M Donald
MD
Britton
Keith E
KE
Carlsen
Ove
O
Cosgriff
Philip
P
Fine
Eugene
E
Fleming
John
J
Nimmon
Cyril
C
Piepsz
Amy
A
Prigent
Alain
A
Samal
Martin
M
D003936:Diagnosis, Computer-Assisted / Q000592:standards*; D006801:Humans; D038622:Internationality; D007674:Kidney Diseases / Q000175:diagnosis*; D009398:Nephrology / Q000592:standards*; D017410:Practice Guidelines as Topic; D010818:Practice Patterns, Physicians' / Q000592:standards*; D011866:Radioisotope Renography / Q000592:standards*; D014572:Urology / Q000592:standards*