title: Cervical actinomycosis with spinal cord compression. Case report and literature review.
abstract: Cervical actinomycosis with spinal cord compression is extremely rare. The clinical presentation of spinal actinomycosis may be nonspecific and back pain is the most consistent early symptom. Here, we present such a case with fever, pain in the neck and upper back, progressive weakness and numbness in all 4 limbs with difficulty ambulating, constipation and uroschesis. Correct diagnosis is difficult because the clinical and radiological findings of actinomycosis closely resemble metastatic tumors and other infectious processes. Timely surgical debridement and decompression contributed to the prompt improvement of the patient's conditions, and histopathological demonstration of the inflammatory granulation tissue and Gram-positive sulfur-containing filamentous bacteria led to the correct diagnosis of actinomycosis. The diagnosis must be made promptly because delayed treatment can result in irreversible neurologic damage or death. Timely and long-term antibacterial therapy is essential for the complete recovery of the patient with actinomycosis.
authors: Department of Pathology, Shanghai Medical College, Fudan University, Shanghai, China.
authors: Guo-Ping
authors: GP
authors: Xu
authors: Zu-De
authors: ZD
authors: Xu
authors: Bu-Lang
authors: BL
authors: Gao
authors: Qi
authors: Q
authors: Chen
authors: Qing-Quan
authors: QQ
authors: Li
authors: Jing-Da
authors: JD
authors: Xu
authors: Hai-Xia
authors: HX
authors: Li
authors: Xi-Xi
authors: XX
authors: Cao
authors: Juan
authors: J
authors: Jing
mesh_terms: D000190:Actinomyces / Q000302:isolation & purification; D000196:Actinomycosis / Q000150:complications* / Q000473:pathology / Q000628:therapy; D000658:Amoxicillin / Q000627:therapeutic use*; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D003646:Debridement; D019299:Decompression, Surgical; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008875:Middle Aged; D013117:Spinal Cord Compression / Q000209:etiology* / Q000601:surgery
chemical_list: D000900:Anti-Bacterial Agents; D000658:Amoxicillin