The structure of melon necrotic spot virus determined at 2.8 A resolution.
The structure of melon necrotic spot virus (MNSV) was determined at 2.8 A resolution. Although MNSV is classified into the genus Carmovirus of the family Tombusviridae, the three-dimensional structure of MNSV showed a higher degree of similarity to tomato bushy stunt virus (TBSV), which belongs to the genus Tombusvirus, than to carnation mottle virus (CMtV), turnip crinkle virus (TCV) or cowpea mottle virus (CPMtV) from the genus Carmovirus. Thus, the classification of the family Tombusviridae at the genus level conflicts with the patterns of similarity among coat-protein structures. MNSV is one of the viruses belonging to the genera Tombusvirus or Carmovirus that are naturally transmitted in the soil by zoospores of fungal vectors. The X-ray structure of MNSV provides us with a representative structure of viruses transmitted by fungi.
Wada
Yasunobu
Y
Institute for Protein Research, Osaka University, 3-2 Yamada-oka, Suita, Osaka 565-0871, Japan.
Tanaka
Hideaki
H
Yamashita
Eiki
E
Kubo
Chikako
C
Ichiki-Uehara
Tamaki
T
Nakazono-Nagaoka
Eiko
E
Omura
Toshihiro
T
Tsukihara
Tomitake
T
D036022:Capsid Proteins / Q000737:chemistry*; D019184:Carmovirus / Q000145:classification / Q000235:genetics / Q000648:ultrastructure*; D018360:Crystallography, X-Ray / Q000379:methods; D028464:Cucurbita / Q000821:virology*; D016679:Genome, Viral; D008958:Models, Molecular; D010935:Plant Diseases / Q000821:virology; D011487:Protein Conformation; D012680:Sensitivity and Specificity
D036022:Capsid Proteins