title: Evaluation of neurologic deficit without apparent cause: the importance of a multidisciplinary approach.
abstract: OBJECTIVE
  A patient presenting with an acute neurologic deficit with no apparent etiology presents a diagnostic dilemma. A broad differential diagnosis must be entertained, considering both organic and psychiatric causes.
  
  
  METHODS
  A case report and thorough literature review of acute paraplegia after a low-energy trauma without a discernible organic etiology.
  
  
  RESULTS
  Diagnostic imaging excluded any bony malalignment or fracture and any abnormality on magnetic resonance imaging. When no organic etiology was identified, a multidisciplinary approach using neurology, psychiatry, and physical medicine and rehabilitation services was applied. Neurophysiologic testing confirmed the absence of an organic disorder, and at this juncture, diagnostic efforts focused on identifying any psychiatric disorder to facilitate appropriate treatment for this individual. The final diagnosis was malingering.
  
  
  CONCLUSIONS
  The full psychiatric differential diagnosis should be considered in the evaluation of any patient with an atypical presentation of paralysis. A thorough clinical examination in combination with the appropriate diagnostic studies can confidently exclude an organic disorder. When considering a psychiatric disorder, the differential diagnosis should include conversion disorder and malingering, although each must remain a diagnosis of exclusion. Maintaining a broad differential diagnosis and involving multiple disciplines (neurology, psychiatry, social work, medical specialists) early in the evaluation of atypical paralysis may facilitate earlier diagnosis and initiation of treatment for the underlying etiology.
authors: Department of Orthopaedic Surgery, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, USA.
authors: Harvey E
authors: HE
authors: Smith
authors: Ralph E
authors: RE
authors: Rynning
authors: Chukwuka
authors: C
authors: Okafor
authors: James
authors: J
authors: Zaslavsky
authors: Joseph I
authors: JI
authors: Tracy
authors: John
authors: J
authors: Ratliff
authors: James
authors: J
authors: Harrop
authors: Todd
authors: T
authors: Albert
authors: Alan
authors: A
authors: Hilibrand
authors: Gregory
authors: G
authors: Anderson
authors: Ashwini
authors: A
authors: Sharan
authors: Zoe
authors: Z
authors: Brown
authors: Alexander R
authors: AR
authors: Vaccaro
mesh_terms: D000208:Acute Disease; D000328:Adult; D003937:Diagnosis, Differential; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008306:Malingering / Q000175:diagnosis* / Q000523:psychology; D009068:Movement / Q000502:physiology; D009422:Nervous System Diseases / Q000175:diagnosis* / Q000209:etiology / Q000523:psychology; D009293:Opioid-Related Disorders / Q000523:psychology; D010264:Paraplegia / Q000175:diagnosis* / Q000209:etiology / Q000523:psychology; D010808:Physical Examination; D011569:Psychiatric Status Rating Scales; D014057:Tomography, X-Ray Computed; D014947:Wounds and Injuries / Q000150:complications