[Acute hemolysis and renal failure caused by hepatitis A infection with underlying glucose-6-phosphate dehydrogenase deficiency].
Although glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common enzyme disorder worldwide, it has rarely been reported among Korean. The patient was previously healthy 39 yr old male who showed severe hemolytic anemia and acute renal failure accompanied by hyperbilirubinemia after hepatitis A infection. The additional studies for differential diagnosis of hemolytic anemia showed a moderate deficiency of G6PD enzyme. Because hepatitis A infection in patient with G6PD deficiency present much more severe clinical symptoms, G6PD enzyme should be examined in patients with triggering factors of hemolysis such as hepatitis A infection.
Jekarl
Dong Wook
DW
Department of Laboratory Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Oh
Eun-Jee
EJ
Park
Yeon-Joon
YJ
Han
KyungJa
K
Lee
Sung Won
SW
Park
Chong-Won
CW
D058186:Acute Kidney Injury / Q000175:diagnosis* / Q000209:etiology; D000328:Adult; D003937:Diagnosis, Differential; D005954:Glucosephosphate Dehydrogenase / Q000235:genetics; D005955:Glucosephosphate Dehydrogenase Deficiency / Q000150:complications* / Q000175:diagnosis; D006461:Hemolysis; D006506:Hepatitis A / Q000150:complications* / Q000175:diagnosis; D017957:Hepatitis A Virus, Human / Q000302:isolation & purification; D006801:Humans; D006932:Hyperbilirubinemia / Q000209:etiology; D008297:Male
D005954:Glucosephosphate Dehydrogenase