title: Bone replacement grafts for the treatment of periodontal intrabony defects.
abstract: Bone replacement grafts, including autogenous grafts from intraoral donor sites, allografts, xenografts, and alloplastic bone substitutes, are the most widely used treatment modalities for the regeneration of periodontal osseous defects. Studies suggest a favorable clinical outcome with the use of these materials in terms of improvements in periodontal probing depths, probing attachment gains, and bone fill. In terms of bone fill, most studies report more than 50% resolution of intrabony defects when treated with bone replacement grafts. However, histologic evidence of periodontal regeneration, including new bone, periodontal ligament, and cementum, has been reported only for autogenous bone grafts and demineralized freeze-dried bone allografts.
authors: Department of Periodontics, Medical College of Georgia, School of Dentistry, 1459 Laney Walker Boulevard, Augusta, GA 30912-1220, USA. phanes@mail.mcg.edu
authors: Philip J
authors: PJ
authors: Hanes
mesh_terms: D016301:Alveolar Bone Loss / Q000601:surgery*; D000539:Alveolar Process / Q000503:physiopathology; D001861:Bone Regeneration / Q000502:physiology; D018786:Bone Substitutes / Q000627:therapeutic use*; D016025:Bone Transplantation; D025021:Cementogenesis / Q000502:physiology; D006801:Humans; D017622:Periodontal Attachment Loss / Q000601:surgery; D010513:Periodontal Ligament / Q000503:physiopathology; D010514:Periodontal Pocket / Q000601:surgery; D016896:Treatment Outcome
chemical_list: D018786:Bone Substitutes