[Peculiarities of meningoencephalitis caused by Angiostrongylus cantonensis in America].
BACKGROUND
25 years ago was first reported in Cuba and in the western hemisphere an emergent disease: eosinophilic meningoencephalitis due to Angiostrongylus cantonensis larvae.


OBJECTIVE
To collect in a summary form the accumulated experience and the findings of the study of this parasitosis during the period in the Western hemisphere.


CONCLUSIONS
There have been collected the first evidences, the parasitological and malacological findings, the experimental and molecular studies on immunology and neuroimmunology, the clinic-pathological findings in children and adults with the particularities of this diseases in our environment with special emphasis in the never-before scientific findings reported. It has been documented the testimony, the main findings among the malacological studies, the role of the immunoglobulin E and the mechanism involved in the central nervous system, the intrathecal synthesis patterns of immunoglobulins and the clinical elements in children and adults.
Dorta-Contreras
A J
AJ
Laboratorio Central de Líquido Cefalorraquídeo, Facultad de Ciencias Médicas Doctor Miguel Enríquez, La Habana, Cuba. adorta@infomed.sld.cu
Núñez-Fernandez
F A
FA
Pérez-Martín
O
O
Lastre-González
M
M
Magraner-Tarrau
M E
ME
Bu-Coifiú Fanego
R
R
Noris-García
E
E
Padilla-Docal
B
B
Interián-Morales
M T
MT
Martínez-Delgado
J F
JF
Sánchez-Zulueta
E
E
D000328:Adult; D017185:Angiostrongylus cantonensis / Q000302:isolation & purification / Q000502:physiology; D000818:Animals; D000909:Antibodies, Helminth / Q000276:immunology; D001210:Asia, Southeastern / Q000208:ethnology; D002648:Child; D002675:Child, Preschool; D003462:Cuba / Q000453:epidemiology; D004199:Disease Vectors; D054242:Emigrants and Immigrants; D004802:Eosinophilia / Q000209:etiology; D006790:Host-Parasite Interactions; D006801:Humans; D007073:Immunoglobulin E / Q000134:cerebrospinal fluid / Q000276:immunology; D007074:Immunoglobulin G / Q000134:cerebrospinal fluid / Q000276:immunology; D007223:Infant; D007843:Latin America / Q000453:epidemiology; D008590:Meningoencephalitis / Q000097:blood / Q000453:epidemiology / Q000276:immunology / Q000469:parasitology* / Q000473:pathology; D051381:Rats / Q000469:parasitology; D012908:Snails / Q000469:parasitology; D017206:Strongylida Infections / Q000097:blood / Q000453:epidemiology* / Q000276:immunology / Q000473:pathology / Q000635:transmission; D014481:United States / Q000453:epidemiology
D000909:Antibodies, Helminth; D007074:Immunoglobulin G; D007073:Immunoglobulin E