title: Mesial temporal sclerosis in children.
abstract: Mesial temporal sclerosis is the most frequent cause of drug-resistant temporal lobe epilepsy but has a satisfactory response to surgery, and is considered infrequent in children.
  
  
  OBJECTIVE
  To evaluate the clinical, electrographic and radiological spectrum of the disease in children.
  
  
  METHODS
  Retrospective study by review of charts of 44 children with a diagnosis of mesial temporal sclerosis on magnetic resonance imaging, attended at the "Hospital das Clínicas" of the University of São Paulo Faculty of Medicine.
  
  
  RESULTS
  Febrile seizure was identified in the history of 54% of the patients. Injuries at the left side predominated in patients with schooling difficulties (p=0.049), in those with first seizures between six months and five years (p=0.021) and in those with complex febrile seizure (p=0.032). Thirteen patients were submitted to surgery and of these, eight remained without seizures.
  
  
  CONCLUSIONS
  Febrile seizure may be related in a more direct way to the presence of left-side mesial temporal sclerosis.
authors: Divisão de Neurologia, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, Rua Vicente Oropallo 612, São Paulo, SP, Brazil. sermaju@uol.com.br
authors: Eliana Maria Domingues
authors: EM
authors: Brandão
authors: Maria Luiza Giraldes de
authors: ML
authors: Manreza
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D004569:Electroencephalography; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D012189:Retrospective Studies; D012598:Sclerosis; D003294:Seizures, Febrile / Q000209:etiology*; D013702:Temporal Lobe / Q000473:pathology* / Q000601:surgery