title: Evaluation of therapeutic response of tuberculoma using F-18 FDG positron emission tomography.
abstract: BACKGROUND
  Monitoring the response to antituberculosis (anti-TB) treatment can be difficult in patients with tuberculoma. We have retrospectively assessed the ability of F-18 fluoro-2-deoxy-D-glucose positron emission tomography (FDG-PET) to evaluate the response to anti-TB treatment in patients with tuberculoma.
  
  
  METHODS
  Two patients with tuberculoma underwent repeat PET scans during anti-TB treatment. Changes in maximal standard uptake value (SUV) of the tuberculoma on PET images were analyzed between 2 scans. Initial PET scans were performed before the start of anti-TB treatment (T0), and later scans were performed after completion of treatment (T1).
  
  
  RESULTS
  In a 57-year-old female patient with clinical TB, maximal SUV of tuberculoma on PET scan decreased from 2.6 (at T0) to an undetectable value (at T1) at an interval of 187 days. In a 60-year-old woman with biopsy-proven TB, maximal SUV of tuberculoma on PET scan decreased from 4.8 (at T0) to 1.1 (at T1) at an interval of 192 days.
  
  
  CONCLUSIONS
  PET scans may be useful for monitoring responses to anti-TB treatment in patients with tuberculoma.
authors: Division of Pulmonology and Critical Care Medicine, University of Ulsan College of Medicine, Asan Medical Center, Songpa-Gu, Seoul, Korea.
authors: I-Nae
authors: IN
authors: Park
authors: Jin-Sook
authors: JS
authors: Ryu
authors: Tae Sun
authors: TS
authors: Shim
mesh_terms: D000995:Antitubercular Agents / Q000627:therapeutic use; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008297:Male; D008875:Middle Aged; D019275:Radiopharmaceuticals; D012189:Retrospective Studies; D014055:Tomography, Emission-Computed; D016896:Treatment Outcome; D014375:Tuberculoma / Q000000981:diagnostic imaging* / Q000188:drug therapy*; D014397:Tuberculosis, Pulmonary / Q000000981:diagnostic imaging* / Q000188:drug therapy*
chemical_list: D000995:Antitubercular Agents; D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18