title: Low intensity laser therapy is comparable to bromocriptine-evening primrose oil for the treatment of cyclical mastalgia in Egyptian females.
abstract: One of the successful treatments for cyclical mastalgia is bromocriptine evening primrose combination. A double blind study was applied on 80 patients with cyclical mastalgia. They were randomly divided into two groups (A and B). In group A, patients were treated by bromocriptine/evening primrose. To group B, LILT with specified dosimetry was applied, using a device that delivers He-Ne laser combined with 4 infra-red diode laser. Evaluation of treatment was both subjective (using VAS) and objective (studying the degree of drop in plasma cortisol level). The drop of plasma cortisol with treatment was studied using the student -t distribution. A good response was observed in the laser group in 82.5%, compared to 63.9% in the bromocriptine/evening primrose group. There was a significant deference before and after treatment in both groups (P<0.05). This difference was more for the drug treated group than for the laser treated group, but in the latter, it acted on a wider sector of patients. In conclusion, LILT is recommended as a new treatment modality for cyclical mastalgia.
authors: Department of General Surgery, Faculty of Medicine, Cairo University, Egypt.
authors: G M
authors: GM
authors: Saied
authors: R M
authors: RM
authors: Kamel
authors: N
authors: N
authors: Dessouki
mesh_terms: D000328:Adult; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage / Q000627:therapeutic use*; D001941:Breast Diseases / Q000188:drug therapy* / Q000532:radiotherapy*; D001971:Bromocriptine / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D004311:Double-Blind Method; D004359:Drug Therapy, Combination; D004534:Egypt; D005260:Female; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D008041:Linoleic Acids / Q000008:administration & dosage / Q000627:therapeutic use*; D028022:Low-Level Light Therapy / Q000379:methods*; D031665:Oenothera biennis; D010147:Pain Measurement; D010938:Plant Oils / Q000008:administration & dosage / Q000627:therapeutic use*; D017965:gamma-Linolenic Acid / Q000008:administration & dosage / Q000627:therapeutic use*
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D008041:Linoleic Acids; D010938:Plant Oils; D001971:Bromocriptine; C028498:evening primrose oil; D017965:gamma-Linolenic Acid; D006854:Hydrocortisone