Dimerization of acetoacetamide leading to 5-carbamoyl-4,6-dimethyl-2-pyridone.
The dimerization of acetoacetamide easily proceeds at room temperature in a dimethyl sulfoxide solution to afford 5-carbamoyl-4,6-dimethyl-2-pyridone.
Nishiwaki
Nagatoshi
N
Department of Chemistry, Osaka Kyoiku University, Kashiwara, Osaka, Japan. nishi@cc.osaka-kyoiku.ac.jp
Nakaike
Yumi
Y
Ariga
Masahiro
M
D000081:Acetamides / Q000737:chemistry*; D000075202:Contraindications; D019281:Dimerization; D004121:Dimethyl Sulfoxide / Q000737:chemistry*; D011728:Pyridones / Q000138:chemical synthesis* / Q000737:chemistry
D000081:Acetamides; D011728:Pyridones; D004121:Dimethyl Sulfoxide