title: Aneurysm Sac pressure measurement with minimally invasive implantable pressure sensors: an alternative to current surveillance regimes after EVAR?
abstract: Current protocols for surveillance after endovascular repair (EVAR) of abdominal aortic aneurysms are mostly based on costly and time-consuming imaging procedures and aim to detect adverse events such as graft migration, endoleaks or aneurysm sac enlargement. These imaging procedures are either associated with radiation exposure to the patients or may be harmful to the patient due to the use of iodine- or gadolinium-containing contrast agents. Furthermore the advantages of EVAR in the short term might be negated by the necessity for endograft surveillance over years. Thus, alternative modalities for follow-up are being investigated. One of these technologies provides pressure information directly from the aneurysm sac. This noninvasive, telemetric pressure sensing was tested in vitro as well as in first clinical trials and was able to identify successful aneurysm exclusion after EVAR. The telemetric pressure sensors showed a promising efficacy and accuracy in detecting type I and type III endoleaks and will help to clarify the clinical relevance of type II endoleaks. This article provides an overview of the in vitro sensors investigated as well as the first clinical trials and the sensors' potential to change the current endograft surveillance regimes.
authors: Applied Medical Engineering, Helmholtz Institute for Biomedical Engineering, RWTH Aachen University, Pauwelsstrasse 20, 52074 Aachen, Germany. fabian.springer@med.uni-tuebingen.de
authors: Fabian
authors: F
authors: Springer
authors: Rolf W
authors: RW
authors: Günther
authors: Thomas
authors: T
authors: Schmitz-Rode
mesh_terms: D017130:Angioplasty / Q000009:adverse effects / Q000379:methods*; D000818:Animals; D017544:Aortic Aneurysm, Abdominal / Q000175:diagnosis / Q000401:mortality / Q000601:surgery*; D002986:Clinical Trials as Topic; D004195:Disease Models, Animal; D004285:Dogs; D004867:Equipment Design; D004869:Equipment Safety; D005260:Female; D006801:Humans; D008297:Male; D019060:Minimally Invasive Surgical Procedures / Q000379:methods; D008991:Monitoring, Physiologic / Q000295:instrumentation* / Q000379:methods; D011183:Postoperative Complications / Q000175:diagnosis*; D011312:Pressure; D012008:Recurrence; D012680:Sensitivity and Specificity; D013552:Swine; D014160:Transducers, Pressure