title: Highly diastereoselective addition of cinnamylzinc derivatives to alpha-chiral carbonyl compounds.
abstract: Cinnamylzinc reagents react with cyclic and acyclic alpha-chiral ketones under very mild conditions (-78 degrees C, 1 h), yielding the corresponding homoallylic alcohols bearing three adjacent stereocenters with high diastereoselectivity. An extension of this reaction to enantioenriched alpha-chiral ketones is also described.
authors: Department Chemie und Biochemie, Ludwig-Maximilians-Universität, Butenandtstrasse 5-13, 81377 München, Germany.
authors: Guillaume
authors: G
authors: Dunet
authors: Peter
authors: P
authors: Mayer
authors: Paul
authors: P
authors: Knochel