title: Severe rhabdomyolysis after excessive bodybuilding.
abstract: A 46-year-old male subject performed excessive physical exertion during 4-6 h in a studio for body builders during 5 days. He was not practicing sport prior to this training and denied the use of any aiding substances. Despite muscle aching already after 1 day, he continued the exercises. After the last day, he recognized tiredness and cessation of urine production. Two days after discontinuation of the training, a Herpes simplex infection occurred. Because of acute renal failure, he required hemodialysis. There were absent tendon reflexes and creatine kinase (CK) values up to 208 274 U/L (normal: <170 U/L). After 2 weeks, CK had almost normalized and, after 4 weeks, hemodialysis was discontinued. Excessive muscle training may result in severe, hemodialysis-dependent rhabdomyolysis. Triggering factors may be prior low fitness level, viral infection, or subclinical metabolic myopathy.
authors: Rudolfstiftung Hospital, Vienna Austria. duarte@aonmail.at
authors: J
authors: J
authors: Finsterer
authors: G
authors: G
authors: Zuntner
authors: M
authors: M
authors: Fuchs
authors: A
authors: A
authors: Weinberger
mesh_terms: D001317:Austria; D003444:Crush Syndrome / Q000503:physiopathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009211:Myoglobin / Q000378:metabolism; D006435:Renal Dialysis; D051437:Renal Insufficiency; D012206:Rhabdomyolysis / Q000209:etiology* / Q000503:physiopathology; D012720:Severity of Illness Index; D014891:Weight Lifting / Q000502:physiology*
chemical_list: D009211:Myoglobin