Demonstration of a bio-microactuator powered by vascular smooth muscle cells coupled to polymer micropillars.
We have demonstrated the working principle of a bio-microactuator using smooth muscle cells (SMCs) by driving micropillars coupled to cultured SMCs and controlled pillar displacements by chemical stimuli; the generated driving force was estimated to be over 1.1 microN.
Tanaka
Yo
Y
Department of Applied Chemistry, School of Engineering, The University of Tokyo, 7-3-1 Hongo, Tokyo, 113-8656, Japan.
Sato
Kae
K
Shimizu
Tatsuya
T
Yamato
Masayuki
M
Okano
Teruo
T
Manabe
Ichiro
I
Nagai
Ryozo
R
Kitamori
Takehiko
T
D000818:Animals; D001011:Aorta / Q000166:cytology; D008297:Male; D046210:Microfluidic Analytical Techniques; D032389:Myocytes, Smooth Muscle / Q000378:metabolism*; D011108:Polymers / Q000737:chemistry* / Q000378:metabolism*; D051381:Rats; D014661:Vasoconstriction
D011108:Polymers