title: [Production of antibacterial substances by resident corynebacteria isolated from human skin].
abstract: Coryneform bacteria, especially lipophilic species, form stable but not dominant population on a human skin. This position is probably controlled by secretion of bacteriocin-like substances, which act directly on coexisting bacteria. Among 118 investigated corynebacteria belonging to seven species/taxa and isolated from human skin, 90% possessed an ability to produce such substances. The spectrum of their activity was restricted to killing gram-positive bacteria, but along with corynebacteria it also covered cocci, with Staphylococcus aureus in this group. This feature was revealed better on low pH media (pH 5.6) and media with 1.5% NaCl for cocci, but on pH 7,4 for corynebacteria.
authors: Zakład Mikrobiologii Farmaceutycznej UM w Łodzi.
authors: Anna
authors: A
authors: Kwaszewska
authors: Eligia M
authors: EM
authors: Szewczyk
mesh_terms: D000900:Anti-Bacterial Agents / Q000096:biosynthesis* / Q000494:pharmacology; D000898:Antibiosis / Q000502:physiology; D001430:Bacteriocins / Q000096:biosynthesis* / Q000494:pharmacology; D003352:Corynebacterium / Q000145:classification / Q000302:isolation & purification / Q000378:metabolism*; D006801:Humans; D012867:Skin / Q000382:microbiology*; D013045:Species Specificity; D013211:Staphylococcus aureus / Q000187:drug effects
chemical_list: D000900:Anti-Bacterial Agents; D001430:Bacteriocins