title: A prospective evaluation of factors associated with chorioretinitis in patients with West Nile virus infection.
abstract: OBJECTIVE
  To identify factors associated with the development and severity of chorioretinitis (CR) in patients with West Nile virus (WNV) infection.
  
  
  METHODS
  Prospective study of 38 patients with WNV infection.
  
  
  RESULTS
  Simple analysis showed that diabetes (p = 0.027) and age older than 45 years (p = 0.03) were significantly associated with CR. When controlling for age, only association between diabetes and CR remains statistically significant. Diabetic patients' eyes were more likely to have macular involvement (p < 0.0001), 20 or more chorioretinal lesions (p < 0.001), and lesion size 500 microm or more (p < 0.01).
  
  
  CONCLUSIONS
  Diabetes was a risk factor for the development and severity of WNV-associated CR.
authors: Department of Ophthalmology, Fattouma Bourguiba University Hospital, Monastir, Tunisia. moncef.khairallah@rns.tn
authors: Moncef
authors: M
authors: Khairallah
authors: Salim Ben
authors: SB
authors: Yahia
authors: Mondher
authors: M
authors: Letaief
authors: Sonia
authors: S
authors: Attia
authors: Rim
authors: R
authors: Kahloun
authors: Bechir
authors: B
authors: Jelliti
authors: Sonia
authors: S
authors: Zaouali
authors: Riadh
authors: R
authors: Messaoud
mesh_terms: D000328:Adult; D000914:Antibodies, Viral / Q000097:blood; D002825:Chorioretinitis / Q000175:diagnosis / Q000821:virology*; D048909:Diabetes Complications; D004797:Enzyme-Linked Immunosorbent Assay; D015828:Eye Infections, Viral / Q000175:diagnosis / Q000821:virology*; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D007075:Immunoglobulin M / Q000032:analysis; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012307:Risk Factors; D014901:West Nile Fever / Q000175:diagnosis / Q000821:virology*; D014902:West Nile virus / Q000276:immunology / Q000302:isolation & purification*
chemical_list: D000914:Antibodies, Viral; D007075:Immunoglobulin M