title: Deep orbital Sub-Q restylane (nonanimal stabilized hyaluronic acid) for orbital volume enhancement in sighted and anophthalmic orbits.
abstract: OBJECTIVE
  To describe a new technique of injecting Restylane Sub-Q (Q-Med, Uppsala, Sweden) into the intraconal and extraconal posterior orbit.
  
  
  METHODS
  Retrospective review. Eight injections were performed in 5 patients using 2-mL Sub-Q in the intraconal and extraconal posterior orbit for orbital volume enhancement. Four injections were performed in sighted orbits and the remaining in anophthalmic orbits. The age range was 18 to 36 years; the follow-up time was 5 to 12 months.
  
  
  RESULTS
  Orbital volume enhancement was achieved in all cases with an improvement in upper eyelid sulcus and skin fold. Enophthalmos reduction was 2 mm per 2-mL injection. The procedure was well tolerated. One patient experienced a vasovagal episode lasting 3 hours and 1 patient had postoperative pain. No such episodes occurred after I began injecting local anesthesia before performing the Sub-Q injection. One patient required hyaluronidase for migrating gel, which caused lower eyelid swelling.
  
  
  CONCLUSIONS
  This small case series suggested the safety and tolerability of deep orbital Sub-Q. Injections are easily performed in the outpatient setting. The expected volume enhancement was achieved in all cases with no long-term adverse effects to date.
authors: Corneo-Plastic Unit, Queen Victoria Hospital, Holtye Road, East Grinstead RH19 3DZ, West Sussex, England. malhotraraman@hotmail.com
authors: Raman
authors: R
authors: Malhotra
mesh_terms: D000293:Adolescent; D000328:Adult; D000853:Anophthalmos / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000503:physiopathology; D001837:Body Weights and Measures; D015841:Enophthalmos / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000517:prevention & control*; D005260:Female; D006801:Humans; D006820:Hyaluronic Acid / Q000008:administration & dosage / Q000031:analogs & derivatives*; D007267:Injections; D008279:Magnetic Resonance Imaging; D008297:Male; D009915:Orbit / Q000000981:diagnostic imaging / Q000187:drug effects* / Q000503:physiopathology; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed
chemical_list: D006820:Hyaluronic Acid; C445361:Restylane