Autophagy and cell death: no longer at odds.
Autophagy has been associated with both cell survival and cell death, but the role of autophagy in cell death has been controversial. In this issue, Berry and Baehrecke (2007) report that autophagy is involved in physiological cell death during Drosophila development and is controlled by similar mechanisms as those that control its function in cell survival.
Bergmann
Andreas
A
The University of Texas MD Anderson Cancer Center, Department of Biochemistry and Molecular Biology, 1515 Holcombe Boulevard-Unit 1000, Houston, TX 77030, USA. abergman@mdanderson.org
D000818:Animals; D001343:Autophagy; D016923:Cell Death; D002470:Cell Survival; D004330:Drosophila