Effect of chemotherapy on primary mucosa-associated lymphoid tissue lymphoma of the orbit.
OBJECTIVE
To present a treatment plan for localized mucosa-associated lymphoid tissue lymphoma of the orbit in order to preserve vital structures and function from the side effects of radiotherapy.


METHODS
Study of 2 clinical cases by means of clinical and radiologic examination, with 2 and 3 years follow-up, respectively.


RESULTS
Immediate remission of the disease after 6 cycles of chemotherapy, with no signs of recurrence after 2 and 3 years. Clinical examination of the oculomotor mechanism and visual activity gave excellent results.


CONCLUSIONS
Although radiotherapy is preferable for localized lymphoproliferative lesions, chemotherapy should also be considered as an effective treatment that preserves the integrity and function of the ocular adnexa.
Dimitrakopoulos
Ioannis
I
University Clinic of Oral and Maxillofacial Surgery, G. Papanikolaou General Hospital, Thessaloniki, Greece. idim@dent.auth.gr
Venetis
Grigorios
G
Kaloutsi
Vasiliki
V
Sotiropoulos
Damianos
D
Papadimitriou
Constantinos
C
D000368:Aged; D015703:Antigens, CD / Q000032:analysis; D014408:Biomarkers, Tumor / Q000032:analysis; D004359:Drug Therapy, Combination; D005094:Exophthalmos / Q000209:etiology; D005260:Female; D006801:Humans; D018442:Lymphoma, B-Cell, Marginal Zone / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000517:prevention & control; D009918:Orbital Neoplasms / Q000188:drug therapy*; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
D015703:Antigens, CD; D014408:Biomarkers, Tumor