title: Synthesis of a quaternary polyprenyl ammonium salt.
abstract: Reaction of primary C(55)-allylic alcohol moraprenol (WT(3)C(7-9)-OH, a polyprenol from mulberry leaves) with triethylamine in the presence of phosphorus oxychloride leads to a quaternary ammonium chloride with a good yield (72%) and high cis-stereoselectivity of the terminal isoprene unit. Cationic polyprenyl derivatives may be useful for transfection and immunological studies.
authors: Kochetkov Laboratory of Carbohydrate Chemistry, Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russian Federation. olga_sizova@yahoo.co.uk
authors: Olga V
authors: OV
authors: Sizova
authors: Natalia S
authors: NS
authors: Utkina
authors: Nadezhda A
authors: NA
authors: Kalinchuk
authors: Leonid L
authors: LL
authors: Danilov
authors: Sergey D
authors: SD
authors: Maltsev
mesh_terms: D009682:Magnetic Resonance Spectroscopy; D000644:Quaternary Ammonium Compounds / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D000644:Quaternary Ammonium Compounds