[Current views of the histogenesis and pathogenesis of Hodgkin lymphoma].
The diagnosis of Hodgkin lymphoma is based on the identification of Beresovsky-Reed-Sternberg (B-R-S) cells which are surrounded by inflammatory cells. The tumor cells are of B-cell origin and their mutations are sometimes observed. T-cell immunophenotype is recorded in 5% of the observations. Epstein-Barr virus is found in one third of the patients.
Leenman
E E
EE
D001402:B-Lymphocytes / Q000276:immunology / Q000473:pathology* / Q000821:virology; D020031:Epstein-Barr Virus Infections / Q000175:diagnosis / Q000235:genetics / Q000276:immunology / Q000473:pathology; D004854:Herpesvirus 4, Human / Q000235:genetics / Q000276:immunology; D006689:Hodgkin Disease / Q000175:diagnosis / Q000235:genetics / Q000276:immunology / Q000473:pathology* / Q000821:virology; D006801:Humans; D016130:Immunophenotyping; D007249:Inflammation / Q000175:diagnosis / Q000235:genetics / Q000473:pathology / Q000821:virology; D016539:Reed-Sternberg Cells / Q000276:immunology / Q000473:pathology* / Q000821:virology; D013601:T-Lymphocytes / Q000276:immunology / Q000473:pathology* / Q000821:virology