title: Post-colonoscopic Listeria septicemia in ulcerative colitis during immunosuppressive therapy.
abstract: A 78-year-old man who had been diagnosed with ulcerative colitis was admitted because of uncontrolled severe, frequent, bloody diarrhea. He was treated with immunosuppressive therapy that included corticosteroid and azathioprine. Colonoscopy was used to assess disease activity. This revealed that the mucosa of his digestive tract from the rectum to the ileum was damaged. He developed a high-grade fever soon after colonoscopy. Blood culture demonstrated Listeria monocytogenes. Treatment was changed to intravenous ampicillin for 20 days. His general body symptoms, including the bloody diarrhea, improved after treatment. We assume that the colonoscopy induced Listeria monocytogenes septicemia through bacterial translocation in this patient.
authors: Department of Infection and Prevention Medicine, Nagoya City University Graduate School of Medical Sciences, Nagoya. minami@med.nagoya-cu.ac.jp
authors: Masaaki
authors: M
authors: Minami
authors: Tadao
authors: T
authors: Hasegawa
authors: Takafumi
authors: T
authors: Ando
authors: Osamu
authors: O
authors: Maeda
authors: Teruko
authors: T
authors: Ohkura
authors: Michio
authors: M
authors: Ohta
authors: Hidemi
authors: H
authors: Goto
mesh_terms: D000368:Aged; D018988:Bacterial Translocation; D003093:Colitis, Ulcerative / Q000188:drug therapy* / Q000473:pathology; D003113:Colonoscopy / Q000009:adverse effects*; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D007413:Intestinal Mucosa / Q000382:microbiology / Q000473:pathology; D008089:Listeria monocytogenes / Q000502:physiology*; D008088:Listeriosis / Q000175:diagnosis / Q000209:etiology*; D008297:Male; D012307:Risk Factors; D018805:Sepsis / Q000175:diagnosis / Q000209:etiology*
chemical_list: D007166:Immunosuppressive Agents