Intranasal midazolam Vs ketamine as premedication in paediatric surgical procedure for child separation and induction.
In children pre-anaesthetic medications are frequently administered as pharmacological adjunctions to help alleviate the stress and fear of surgery as well as to ease child parental separation and promote a smooth induction. Oral, rectal, intravenous and intramuscular route has been used; however each route has its disadvantage. Pre-anaesthetic medication administered intranasal for avoidance of painful injection have made it a convenient way to pre-medication. To evaluate the efficacy of intranasal administered Midazolam 0.2 mg/kg and Ketamine 5 mg/kg respectively. Total 50 patients of ASA I and II of age group 1- 7 years, mean age 3.88 +/- 1.26 and 4.56 +/- 1.21 were included in group I and group II respectively, and Scheduled for elective surgery. Mean time of separation was 17.12 +/- 1.21 in-group I and 15.68+11.62 in group II with P value < 0.001 and 0.322, shows significant difference during time of separation from parents and no significant difference for i.v. line insertion in both groups.
Gautam
Shailendra Nath
SN
Department of Anaesthesia, Nepal Medical College Teaching Hospital Jorpati, Kathmandu, Nepal.
Bhatta
Shrikrishna
S
Sangraula
Daisy
D
Shrestha
Bishow Chandra
BC
Rawal
Sharad Bahadur
SB
D000281:Administration, Intranasal; D000778:Anesthetics, Dissociative; D014151:Anti-Anxiety Agents / Q000008:administration & dosage* / Q000494:pharmacology; D002648:Child; D002673:Child, Hospitalized / Q000523:psychology; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008874:Midazolam / Q000008:administration & dosage* / Q000494:pharmacology; D010287:Parent-Child Relations; D011229:Preanesthetic Medication; D011300:Preoperative Care; D013997:Time Factors
D000778:Anesthetics, Dissociative; D014151:Anti-Anxiety Agents; D008874:Midazolam