title: Review article: Management of diverticulitis.
abstract: OBJECTIVE
  The incidence and therefore complications of (sigmoid) diverticular disease are increasing.
  
  
  METHODS
  Review of current literature.
  
  
  RESULTS
  From all patients, 15% will develop diverticulitis, 5% complications and 5% diverticular bleeding. Diagnosis is established with computerised tomography. Colonoscopy is needed to rule out malignancy. NSAIDs increase the risk of perforation; steroids, diabetes, collagen vascular disease and immune compromised are associated with complicated disease and death. In mild diverticulitis, antibiotics are recommended. In complicated disease with abscesses, <5 cm antibiotics are sufficient. Larger abscesses are drained under computerised tomography-guidance. Peritonitis forms an indication for surgery. Diverticulitis recurrence rate is around 30%, most are uncomplicated. Recurrence after surgery is around 10%. Elective surgery is reserved for fistula closure and obstruction. The need for elective surgery to prevent recurrence has diminished because of new insights. Important is to identify risk groups. New issues are the possible relationship between diverticulitis and cancer, segmental colitis associated with diverticulitis, and treatment of diverticulitis with mesalazine and probiotics.
  
  
  CONCLUSIONS
  Uncomplicated diverticulitis is treated medically. Complicated diverticulitis with small abscesses is treated with antibiotics while larger abscesses are drained with computerised tomography-guided puncture. Emergency surgery is reserved for peritonitis, elective surgery for fistula/stenosis. Surgery to prevent recurrence is indicated only in selected cases (e.g. immune compromised).
authors: Department of Gastroenterology and Hepatology, VU University Medical Centre, Amsterdam, The Netherlands.
authors: M M
authors: MM
authors: Szojda
authors: M A
authors: MA
authors: Cuesta
authors: C M
authors: CM
authors: Mulder
authors: R J F
authors: RJ
authors: Felt-Bersma
mesh_terms: D004239:Diverticulitis, Colonic / Q000209:etiology / Q000628:therapy*; D006801:Humans; D011379:Prognosis; D055502:Secondary Prevention; D012810:Sigmoid Diseases / Q000209:etiology / Q000628:therapy*