Diterpenes, sesquiterpenes, and a C15-acetogenin from the marine red alga Laurencia mariannensis.
In addition to 10 known compounds (7- 16), one new brominated diterpene, 10-hydroxykahukuene B (1), two new sesquiterpenes, 9-deoxyelatol (2) and isodactyloxene A (3), one new brominated C 15-acetogenin, laurenmariallene (4), and two new naturally occurring halogenated sesquiterpenes (5 and 6) that were previously obtained as intermediates in a biomimetic synthetic study of rhodolaureol and rhodolauradiol have been isolated and identified from the organic extract of the marine red alga Laurencia mariannensis. The structures of these compounds were established by spectroscopic methods. The antibacterial and antifungal activities of new compounds 1-4 were evaluated.
Ji
Nai-Yun
NY
Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences, Qingdao, PR China.
Li
Xiao-Ming
XM
Li
Ke
K
Ding
Lan-Ping
LP
Gloer
James B
JB
Wang
Bin-Gui
BG
D054378:Acetogenins / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D000935:Antifungal Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D001234:Aspergillus niger / Q000187:drug effects; D002176:Candida albicans / Q000187:drug effects; D002681:China; D004224:Diterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D004926:Escherichia coli / Q000187:drug effects; D006842:Hydrocarbons, Brominated / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D044722:Laurencia / Q000737:chemistry*; D008386:Marine Biology; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D012717:Sesquiterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D013211:Staphylococcus aureus / Q000187:drug effects
C526835:10-hydroxykahukuene B; C526838:9-deoxyelatol; D054378:Acetogenins; D000900:Anti-Bacterial Agents; D000935:Antifungal Agents; D004224:Diterpenes; D006842:Hydrocarbons, Brominated; D012717:Sesquiterpenes; C526839:isodactyloxene A; C526841:laurenmariallene