Liposomes from a new chiral cationic lipid based on iridoidic template.
A new cationic polyhydroxylated lipid, characterized by a chiral template, was synthesized. It comes from an iridoid glucoside, as polyhydroxylated moiety. This lipid affords liposomes using cholesterol-like co-lipid. The liposomes had a spheroidal shape with a small size distribution.
Bianco
Armandodoriano
A
Dipartimento di Chimica, Università La Sapienza, Piazzale Aldo Moro 5, 00185 Roma, Italy. armandodoriano.bianco@univoma1.it
Napolitano
Raffaella
R
Bonadies
Francesco
F
Celona
Diana
D
Ortaggi
Giancarlo
G
Cametti
Cesare
C
D002412:Cations / Q000737:chemistry*; D039823:Iridoids / Q000737:chemistry*; D008055:Lipids / Q000737:chemistry*; D008081:Liposomes / Q000138:chemical synthesis* / Q000737:chemistry; D008956:Models, Chemical; D015394:Molecular Structure; D013237:Stereoisomerism
D002412:Cations; D039823:Iridoids; D008055:Lipids; D008081:Liposomes