title: Rapid C-carboxylation of nitro[(11)C]methane for the synthesis of ethyl nitro[2-(11)C]acetate.
abstract: The labelling synthesis of ethyl nitro[2-(11)C]acetate, a synthetic intermediate feasible for (11)C-labelled PET tracers, by C-carboxylation of [(11)C]MeNO(2) with 1-ethoxycarbonylbenzotriazole, and its simple application are presented.
authors: Department of Molecular Probes, Molecular Imaging Center, National Institute of Radiological Sciences, Chiba, Japan. katok@nirs.go.jp
authors: Koichi
authors: K
authors: Kato
authors: Ming-Rong
authors: MR
authors: Zhang
authors: Kazutoshi
authors: K
authors: Suzuki
mesh_terms: D000085:Acetates / Q000737:chemistry; D002244:Carbon / Q000378:metabolism*; D002250:Carbon Radioisotopes; D002384:Catalysis; D005240:Feasibility Studies; D008697:Methane / Q000031:analogs & derivatives* / Q000737:chemistry / Q000378:metabolism; D008954:Models, Biological; D009595:Nitroparaffins / Q000737:chemistry / Q000378:metabolism*; D049268:Positron-Emission Tomography; D011849:Radioactive Tracers
chemical_list: D000085:Acetates; D002250:Carbon Radioisotopes; D009595:Nitroparaffins; D011849:Radioactive Tracers; C028257:nitroacetic acid; D002244:Carbon; D008697:Methane; C008640:nitromethane