title: Primary mucinous adenocarcinoma of the bladder with signet-ring cells: case report.
abstract: BACKGROUND
  Primary adenocarcinomas of the bladder are uncommon and usually occur by contiguity with or hematogenic dissemination of other adenocarcinomas such as colorectal, prostate and gynecological tract carcinomas. Mucinous and signet-ring cell histological patterns are even rarer and it is often difficult to morphologically distinguish them from metastatic colorectal adenocarcinoma.
  
  
  METHODS
  We present and discuss a rare case of primary mucinous adenocarcinoma of the bladder with signet-ring cells in a 57-year-old male patient. Other primary sites for the tumor had been excluded and, in the absence of digestive tract tumor and for confirmation that it was a primary bladder tumor, an immunohistochemistry study was performed.
authors: Hospital Professor Edmundo Vasconcelos, São Paulo, Brazil.
authors: Marcelo Lorenzi
authors: ML
authors: Marques
authors: Gabriel Salum
authors: GS
authors: D'Alessandro
authors: Daher Cezar
authors: DC
authors: Chade
authors: Valéria Pereira
authors: VP
authors: Lanzoni
authors: Samuel
authors: S
authors: Saiovici
authors: Cláudio José Ramos de
authors: CJ
authors: Almeida
mesh_terms: D002288:Adenocarcinoma, Mucinous / Q000175:diagnosis*; D018279:Carcinoma, Signet Ring Cell / Q000175:diagnosis*; D006801:Humans; D053554:Keratin-20 / Q000032:analysis; D053552:Keratin-7 / Q000032:analysis; D008297:Male; D008875:Middle Aged; D055262:Mucin-2; D009077:Mucins / Q000032:analysis; D013274:Stomach Neoplasms / Q000175:diagnosis; D001749:Urinary Bladder Neoplasms / Q000175:diagnosis*
chemical_list: D053554:Keratin-20; D053552:Keratin-7; C524625:MUC2 protein, human; D055262:Mucin-2; D009077:Mucins