Evaluation of reflux nephropathy, pyelonephritis and renal dysplasia.
MR urography has the potential to significantly improve our understanding of the relationship between reflux nephropathy, pyelonephritis, vesicoureteric reflux and renal dysplasia. MR urography utilizes multiple parameters to assess both renal anatomy and function and provides a more complete characterization of acquired and congenital disease. Pyelonephritis and renal scarring can be distinguished by assessing the parenchymal contours and signal intensity. Characteristic imaging features of renal dysplasia include small size, subcortical cysts, disorganized architecture, decreased and patchy contrast enhancement as well as a dysmorphic pelvicalyceal system. Because of its ability to subdivide and categorize this heterogeneous group of disorders, it seems inevitable that MR urography will replace DMSA renal scintigraphy as the gold standard for assessment of pyelonephritis and renal scarring. MR urography will contribute to our understanding of renal dysplasia and its relationship to reflux nephropathy.
Grattan-Smith
J Damien
JD
Department of Radiology, Emory University School of Medicine, Children's Healthcare of Atlanta, Atlanta, GA, USA. Damien.grattan-smith@choa.org
Little
Stephen B
SB
Jones
Richard A
RA
D002921:Cicatrix / Q000175:diagnosis; D003287:Contrast Media; D005919:Glomerular Filtration Rate / Q000502:physiology; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D007668:Kidney / Q000002:abnormalities* / Q000503:physiopathology; D007674:Kidney Diseases / Q000175:diagnosis; D008279:Magnetic Resonance Imaging / Q000379:methods*; D011704:Pyelonephritis / Q000175:diagnosis* / Q000503:physiopathology; D014718:Vesico-Ureteral Reflux / Q000175:diagnosis* / Q000503:physiopathology
D003287:Contrast Media