Analysis of chlorothalonil and degradation products in soil and water by GC/MS and LC/MS.
We present a method using gas chromatography (GC) and liquid chromatography (LC) coupled to a mass selective detector to measure concentrations of the fungicide chlorothalonil and several of its metabolites in soil and water. The methods employed solid-phase extraction using a hydrophobic polymeric phase for the isolation of analytes. In lake water, average analyte recoveries ranged from 70% to 110%, with exception of pentachloronitrobenzene that gave low recoveries (23%). The method detection limits were determined to be in the range of 1 and 0.1microg l(-1) for the LC and GC methods, respectively. In soil samples, recoveries ranged from 80% to 95% for 4-hydroxy-2,5,6-trichloroisophthalonitrile (metabolite II) and 1,3-dicarbamoyl-2,4,5,6-tetrachlorobenzene (metabolite III). Limits of detection (LOD) were 0.05 and 0.02microg g(-1), respectively. Chlorothalonil and other metabolites were analyzed by GC giving recoveries ranging from 54% to 130% with LOD of 0.001-0.005microg g(-1).
Chaves
Alicia
A
Department of Environmental and Molecular Toxicology, North Carolina State University, Campus Box 7633, Raleigh, NC 27695, United States. alicia_chaves@hotmail.com
Shea
Damian
D
Danehower
David
D
D001274:Atmospheric Pressure; D002853:Chromatography, Liquid; D008401:Gas Chromatography-Mass Spectrometry; D028521:Musa; D009570:Nitriles / Q000032:analysis* / Q000737:chemistry* / Q000378:metabolism; D012987:Soil / Q000032:analysis*; D021241:Spectrometry, Mass, Electrospray Ionization; D014867:Water / Q000737:chemistry*
D009570:Nitriles; D012987:Soil; D014867:Water; C005806:tetrachloroisophthalonitrile