title: Lymphoepithelial lesions of the parotid gland in the HIV era--a South African experience.
abstract: OBJECTIVE
  Historically, lymphoepithelial lesions (LELs) have been a peripheral indication for surgery on the parotid gland, accounting for less than 1% of all parotidectomies undertaken. In the HIV era the profile of parotidectomy has changed, with LEL becoming a common indication for parotidectomy, prompting a review of our current experience.
  
  
  METHODS
  A retrospective study was undertaken between January 1998 and December 2005. Setting. Surgical services at King Edward VIII Hospital, Durban.
  
  
  METHODS
  All patients presenting with parotidomegaly.
  
  
  RESULTS
  One hundred and sixty-two patients with parotidomegaly were evaluated; 53 (32.7%) had LEL lesions. A total of 151 parotidectomies (including 42 parotidectomies undertaken for LEL lesions) were performed in 147 patients. Radiotherapy was offered to 11 patients with LEL lesions. Complications following parotidectomy for LEL included facial nerve palsy (N=3), seroma formation (N=5) and facial artery false aneurysm (N=1). Three patients required re-parotidectomy for recurrent LEL parotidomegaly. In the patients who underwent radiotherapy, there was a satisfactory outcome; 2 patients who received 4 Gy radiation per sitting developed mild skin discolouration of the treated area.
  
  
  CONCLUSIONS
  Although surgical management of LEL parotidomegaly may provide a satisfactory result, this approach is technically challenging and is associated with complications and recurrences. For these reasons, the non-operative approach employing radiotherapy should be considered.
authors: Department of Surgery, Nelson R. Mandela School of Medicine, University of KwaZulu-Natal, Durban.
authors: M
authors: M
authors: Naidoo
authors: B
authors: B
authors: Singh
authors: P K
authors: PK
authors: Ramdial
authors: J
authors: J
authors: Moodley
authors: L
authors: L
authors: Allopi
authors: B
authors: B
authors: Lester
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D004848:Epithelium / Q000473:pathology*; D005260:Female; D015658:HIV Infections / Q000150:complications / Q000473:pathology / Q000503:physiopathology*; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D010305:Parotid Diseases / Q000209:etiology / Q000473:pathology / Q000601:surgery*; D010306:Parotid Gland / Q000473:pathology*; D012189:Retrospective Studies; D013019:South Africa