Experience with a comprehensive university hospital-based infertility program in Nigeria.
OBJECTIVE
To assess outcome at an infertility management center in Nigeria.


METHODS
Diagnoses were made for 1948 consecutive couples following the World Health Organization guideline on the investigation of infertile couples, treatment was provided, and the couples were followed up over a 10-year period.


RESULTS
The infertility was primary in 14.3% and secondary in 85.7% of cases. Treatment failed in 59.9% and succeeded in 40.1% of cases, resulting in pregnancy for 13.5% of the couples with female infertility factors alone, 6.5% of the couples with male infertility factors alone, and 3.6% of those with both male and female factors. The pregnancy rate was 16.6% for couples with idiopathic infertility.


CONCLUSIONS
Pregnancy outcome was relatively poor because conventional treatments did not cure the most prevalent causes of infertility, and assisted reproductive technology is therefore advocated.
Orhue
Augustine
A
Human Reproduction Research Program Unit, Department of Obstetrics and Gynecology, University of Benin Teaching Hospital, Benin City, Edo State, Nigeria. aaeorhue@yahoo.com
Aziken
Michael
M
D000328:Adult; D005260:Female; D005500:Follow-Up Studies; D006785:Hospitals, University; D006801:Humans; D007246:Infertility / Q000175:diagnosis* / Q000209:etiology / Q000628:therapy*; D007247:Infertility, Female / Q000175:diagnosis / Q000209:etiology / Q000628:therapy; D007248:Infertility, Male / Q000175:diagnosis / Q000209:etiology / Q000628:therapy; D008297:Male; D008875:Middle Aged; D009549:Nigeria; D011247:Pregnancy; D011256:Pregnancy Outcome; D018873:Pregnancy Rate; D015995:Prevalence; D012661:Semen