Oligonucleotide synthesis using ionic liquids as soluble supports.
The continuing evolution of the methodology for the solution-phase synthesis of oligonucleotides using soluble ionic tags as handles for easy purification is described. This methodology may provide a more cost efficient route for the large scale synthesis of oligonucleotides.
Donga
Robert A
RA
Department of Chemistry, McGill University, Montreal, Canada.
Hassler
Matthew
M
Chan
Tak-Hang
TH
Damha
Masad J
MJ
D052578:Ionic Liquids / Q000737:chemistry*; D009705:Nucleosides / Q000737:chemistry*; D009841:Oligonucleotides / Q000138:chemical synthesis*
D052578:Ionic Liquids; D009705:Nucleosides; D009841:Oligonucleotides