title: The use of fine needle aspiration cytology for the distinction of pancreatic mucinous neoplasia.
abstract: Cytology frequently has some role in preoperatively distinguishing pancreatic mucus-producing neoplasia (intraductal papillary mucinous neoplasms [IPMNs] and mucinous cystic neoplasms [MCNs]) from other pancreatic cysts. We evaluated all cytologic specimens at our institutions from resected pancreatic cystic lesions for lesional extracellular and cellular material. Lesional extracellular material was identified in 32 of 38 of the cytologic samples from cystic pancreatic mucus-producing neoplasms (28 of 31 IPMNs and 4 of 7 MCNs). Lesional cellular material was seen in 22 of 38 cases (17 of 31 IPMNs and 5 of 7 MCNs). Lesional material was more commonly identified in higher grade and invasive lesions. Lesional extracellular material was seen in 3 of 14 samples of other pancreatic cysts, and lesional cellular material was seen in 6 of 14 cases.
authors: Department of Pathology, Box 800214, University of Virginia Health Sciences, Charlottesville, VA 22908, USA.
authors: Edward B
authors: EB
authors: Stelow
authors: Vanessa M
authors: VM
authors: Shami
authors: Todd E
authors: TE
authors: Abbott
authors: Michelle
authors: M
authors: Kahaleh
authors: Reid B
authors: RB
authors: Adams
authors: Todd W
authors: TW
authors: Bauer
authors: Steven M
authors: SM
authors: Debol
authors: James M
authors: JM
authors: Abraham
authors: Shawn
authors: S
authors: Mallery
authors: Maria Luisa
authors: ML
authors: Policarpio-Nicolas
mesh_terms: D002288:Adenocarcinoma, Mucinous / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D044963:Biopsy, Fine-Needle; D021441:Carcinoma, Pancreatic Ductal / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D003937:Diagnosis, Differential; D019160:Endosonography; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009093:Mucus / Q000378:metabolism; D010179:Pancreas / Q000473:pathology*; D010181:Pancreatic Cyst / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D010190:Pancreatic Neoplasms / Q000378:metabolism / Q000473:pathology* / Q000601:surgery