Buprenorphine in the treatment of opioid dependence.
Methadone has been the mainstay of pharmacological management of opioid dependence since the 1960s but buprenorphine is fast gaining acceptance among addiction specialists and patients. This article provides an overview of buprenorphine, its pharmacology, clinical efficacy and role in the treatment of opioid dependence.
George
Sanju
S
The Bridge, Birmingham and Solihull Mental Health Trust, Chelmsley Wood, Birmingham.
Day
Ed
E
D002047:Buprenorphine / Q000009:adverse effects / Q000493:pharmacokinetics / Q000627:therapeutic use*; D006556:Heroin Dependence / Q000534:rehabilitation*; D006801:Humans; D008691:Methadone / Q000627:therapeutic use; D009292:Narcotic Antagonists / Q000009:adverse effects / Q000493:pharmacokinetics / Q000627:therapeutic use*; D016896:Treatment Outcome
D009292:Narcotic Antagonists; D002047:Buprenorphine; D008691:Methadone