title: Human leukocyte antigen profile of two ethnic groups in Southeast of Iran.
abstract: This study was performed to determine the genetic diversity of HLA class I and II alleles among two ethnic groups in Southeastern Iran. HLA profiles were determined in 71 Iranian populations (41 Zaboli and 30 Baloch). The frequencies of HLA-A02 (p=0.017), -Cw4 (p=0.003), and -DR8 (p=0.025) in the Zaboli populations were significantly higher than that in Baloch ethnic group. In contrast, the frequency of HLA-A23 allele was more frequent in Baloch than Zaboli (p=0.020). This report represents an important resource for investigators in the fields of transplantation immunology and population genetics from widely dispersed areas of Iran.
authors: Zahedan University of Medical Sciences, Sistan and Balochestan, Iran. hkhazaei118@yahoo.com
authors: Hossein Ali
authors: HA
authors: Khazaei
authors: Nima
authors: N
authors: Rezaei
authors: Asghar
authors: A
authors: Aghamohammadi
authors: Ali Akbar
authors: AA
authors: Amirzargar
authors: Khadidjeh
authors: K
authors: Ghasemi
authors: Ibrahim
authors: I
authors: Mirimoghaddam
authors: Behrouz
authors: B
authors: Nikbin
mesh_terms: D005006:Ethnicity; D005828:Genetics, Population; D015395:Histocompatibility Antigens Class I / Q000235:genetics / Q000276:immunology*; D000949:Histocompatibility Antigens Class II / Q000235:genetics / Q000276:immunology*; D006801:Humans; D007492:Iran
chemical_list: D015395:Histocompatibility Antigens Class I; D000949:Histocompatibility Antigens Class II