Polypoid gastrointestinal stromal tumor of small bowel metastasizing to mesenteric lymph nodes: a case report.
Gastrointestinal stromal tumor (GIST) is the commonest gastrointestinal mesenchymal tumor, which rarely metastasizes to lymph nodes. Therefore, unlike cases of adenocarcinoma, lymphadenectomy is seldom warranted. We describe an unusual case of a polypoid GIST of the small bowel which metastasized to the regional mesenteric lymph nodes at the time of primary surgery. The patient was a 79-year-old female who presented with partial bowel obstruction and anemia. The presented case has three unusual features, as the tumor was grossly pedunculated, microscopically pleomorphic, and featured mesenteric lymph node metastasis at the time of diagnosis.
El Demellawy
Dina
D
Department of Pathology, Sunnybrook Health Sciences Center, University of Toronto, 2075 Bayview Avenue, Room E 416, Toronto, ON, Canada M4N 3M5.
Shokry
Phoebe
P
Ing
Alan
A
Khalifa
Mahmoud
M
D000368:Aged; D018952:Antigens, CD34 / Q000378:metabolism; D001161:Arteriosclerosis / Q000473:pathology; D001026:Coronary Artery Bypass; D016894:Endarterectomy, Carotid; D005260:Female; D005756:Gastritis / Q000382:microbiology; D046152:Gastrointestinal Stromal Tumors / Q000378:metabolism / Q000473:pathology*; D016481:Helicobacter Infections; D006801:Humans; D006973:Hypertension / Q000473:pathology; D007150:Immunohistochemistry; D007417:Intestinal Polyps / Q000473:pathology; D007421:Intestine, Small / Q000378:metabolism / Q000473:pathology*; D008207:Lymphatic Metastasis / Q000473:pathology*; D008643:Mesentery / Q000473:pathology*; D019009:Proto-Oncogene Proteins c-kit / Q000378:metabolism; D014746:Vimentin / Q000378:metabolism
D018952:Antigens, CD34; D014746:Vimentin; D019009:Proto-Oncogene Proteins c-kit