Concentrations of resveratrol and derivatives in foods and estimation of dietary intake in a Spanish population: European Prospective Investigation into Cancer and Nutrition (EPIC)-Spain cohort.
Resveratrol has been shown to have beneficial effects on diseases related to oxidant and/or inflammatory processes and extends the lifespan of simple organisms including rodents. The objective of the present study was to estimate the dietary intake of resveratrol and piceid (R&P) present in foods, and to identify the principal dietary sources of these compounds in the Spanish adult population. For this purpose, a food composition database (FCDB) of R&P in Spanish foods was compiled. The study included 40,685 subjects aged 35-64 years from northern and southern regions of Spain who were included in the European Prospective Investigation into Cancer and Nutrition (EPIC)-Spain cohort. Usual food intake was assessed by personal interviews using a computerised version of a validated diet history method. An FCDB with 160 items was compiled. The estimated median and mean of R&P intake were 100 and 933 microg/d respectively. Approximately, 32% of the population did not consume R&P. The most abundant of the four stilbenes studied was trans-piceid (53.6%), followed by trans-resveratrol (20.9%), cis-piceid (19.3%) and cis-resveratrol (6.2%). The most important source of R&P was wines (98.4%) and grape and grape juices (1.6%), whereas peanuts, pistachios and berries contributed to less than 0.01%. For this reason the pattern of intake of R&P was similar to the wine pattern. This is the first time that R&P intake has been estimated in a Mediterranean country.
Zamora-Ros
Raul
R
Nutrition and Food Science Department, XaRTA, INSA, Pharmacy School, University of Barcelona, Av. Joan XXIII, s/n. 08028, Barcelona, Spain.
Andres-Lacueva
Cristina
C
Lamuela-Raventós
Rosa M
RM
Berenguer
Toni
T
Jakszyn
Paula
P
Martínez
Carmen
C
Sánchez
María J
MJ
Navarro
Carmen
C
Chirlaque
María D
MD
Tormo
María-José
MJ
Quirós
Jose R
JR
Amiano
Pilar
P
Dorronsoro
Miren
M
Larrañaga
Nerea
N
Barricarte
Aurelio
A
Ardanaz
Eva
E
González
Carlos A
CA
D000328:Adult; D000367:Age Factors; D000368:Aged; D015331:Cohort Studies; D016208:Databases, Factual; D038441:Diet, Mediterranean / Q000706:statistics & numerical data; D005247:Feeding Behavior; D005260:Female; D005504:Food Analysis / Q000379:methods; D005960:Glucosides / Q000008:administration & dosage / Q000032:analysis; D006801:Humans; D008297:Male; D008875:Middle Aged; D000077185:Resveratrol; D012737:Sex Factors; D013030:Spain; D013267:Stilbenes / Q000008:administration & dosage / Q000032:analysis*; D014920:Wine / Q000032:analysis
D005960:Glucosides; D013267:Stilbenes; D000077185:Resveratrol; C058229:polydatin