title: Influence of exercise on serum brain-derived neurotrophic factor concentrations in healthy human subjects.
abstract: The effect of short-term exercise (15 min step-exercise) on serum brain-derived neurotrophic factor (BDNF) levels was evaluated in healthy human subjects. Results showed a short-term, significant increase in serum BDNF levels after exercise. Intra-individual differences in serum BDNF levels were remarkably small on the rest day and also when compared to rest values on the day of the exercise test. Inter-individual differences, on the other hand, were larger by comparison. The result of this study supports the need for larger sample size in studies on BDNF changes in psychiatric disorders or psychiatric drug effects.
authors: Department of Psychiatry, University of Hong Kong, Hong Kong.
authors: Siu Wa
authors: SW
authors: Tang
authors: Emily
authors: E
authors: Chu
authors: Tomy
authors: T
authors: Hui
authors: Daiga
authors: D
authors: Helmeste
authors: Cindy
authors: C
authors: Law
mesh_terms: D000328:Adult; D001921:Brain / Q000378:metabolism*; D019208:Brain-Derived Neurotrophic Factor / Q000097:blood*; D003866:Depressive Disorder / Q000097:blood / Q000503:physiopathology; D015444:Exercise / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D010809:Physical Fitness / Q000502:physiology*; D018401:Sample Size; D015854:Up-Regulation / Q000502:physiology*
chemical_list: D019208:Brain-Derived Neurotrophic Factor