Human leukocyte antigen profile of two ethnic groups in Southeast of Iran.
This study was performed to determine the genetic diversity of HLA class I and II alleles among two ethnic groups in Southeastern Iran. HLA profiles were determined in 71 Iranian populations (41 Zaboli and 30 Baloch). The frequencies of HLA-A02 (p=0.017), -Cw4 (p=0.003), and -DR8 (p=0.025) in the Zaboli populations were significantly higher than that in Baloch ethnic group. In contrast, the frequency of HLA-A23 allele was more frequent in Baloch than Zaboli (p=0.020). This report represents an important resource for investigators in the fields of transplantation immunology and population genetics from widely dispersed areas of Iran.
Khazaei
Hossein Ali
HA
Zahedan University of Medical Sciences, Sistan and Balochestan, Iran. hkhazaei118@yahoo.com
Rezaei
Nima
N
Aghamohammadi
Asghar
A
Amirzargar
Ali Akbar
AA
Ghasemi
Khadidjeh
K
Mirimoghaddam
Ibrahim
I
Nikbin
Behrouz
B
D005006:Ethnicity; D005828:Genetics, Population; D015395:Histocompatibility Antigens Class I / Q000235:genetics / Q000276:immunology*; D000949:Histocompatibility Antigens Class II / Q000235:genetics / Q000276:immunology*; D006801:Humans; D007492:Iran
D015395:Histocompatibility Antigens Class I; D000949:Histocompatibility Antigens Class II