title: The 2007 Otto Aufranc Award. Ceramic-on-metal hip arthroplasties: a comparative in vitro and in vivo study.
abstract: The performance of novel ceramic-on-metal bearing couples has been compared with metal-on-metal and ceramic-on-ceramic bearing couples in laboratory and short-term clinical studies. Laboratory studies compared ceramic-on-metal with metal-on-metal and ceramic-on-ceramic bearings with diameters of 28 and 36 mm under standard conditions and under adverse conditions with head loading on the rim of the cup. Clinical studies compared metal ion levels in ceramic-on-metal with metal-on-metal, ceramic-on-ceramic, and ceramic-on-polyethylene bearings in a randomized prospective study. In the laboratory studies, friction, wear, and ion levels were lower in ceramic-on-metal bearings compared with metal-on-metal, with results similar to ceramic-on-ceramic couples. Under adverse conditions and rim loading, all bearings showed increased wear with lower wear and absence of stripe wear in ceramic-on-metal compared with metal-on-metal bearings. Short-term studies in 31 patients at 6 months revealed lower metal ion levels (cobalt and chromium) in those with ceramic-on-metal compared with metal-on-metal bearings.
authors: Institute of Medical and Biological Engineering, School of Mechanical Engineering, University of Leeds, Leeds, UK. s.d.williams@leeds.ac.uk
authors: Sophie
authors: S
authors: Williams
authors: Anton
authors: A
authors: Schepers
authors: Graham
authors: G
authors: Isaac
authors: Cath
authors: C
authors: Hardaker
authors: Eileen
authors: E
authors: Ingham
authors: Dick
authors: D
authors: van der Jagt
authors: Anke
authors: A
authors: Breckon
authors: John
authors: J
authors: Fisher
mesh_terms: D000328:Adult; D019644:Arthroplasty, Replacement, Hip / Q000295:instrumentation*; D001363:Awards and Prizes; D002516:Ceramics; D002857:Chromium / Q000097:blood; D002858:Chromium Alloys; D003035:Cobalt / Q000097:blood; D005260:Female; D006621:Hip Joint / Q000503:physiopathology / Q000601:surgery*; D006622:Hip Prosthesis; D006801:Humans; D007592:Joint Diseases / Q000097:blood / Q000503:physiopathology / Q000601:surgery*; D008297:Male; D008422:Materials Testing; D008875:Middle Aged; D011446:Prospective Studies; D011474:Prosthesis Design; D016059:Range of Motion, Articular; D013314:Stress, Mechanical; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D002858:Chromium Alloys; D002857:Chromium; D003035:Cobalt