title: Amphotericin B-induced cutaneous leucocytoclastic vasculitis: case report.
abstract: A 37-year-old female patient was diagnosed with ulcerative colitis 8 months ago and medical treatment with oral azathioprine, low-dose corticosteroids and 5-ASA was started. Following 3 months without any symptoms, the patient had total colectomy and ileostomy. After this period, liposomal amphotericin B (3 mg kg(-1) day(-1)) was given with the diagnosis of probable fungal infection. Palpable purpuric skin lesions on the anterior surface of both legs appeared on the 55th day of amphotericin B treatment. Histological examination of a skin biopsy was consistent with leucocytoclastic vasculitis. We present a case of cutaneous leucocytoclastic vasculitis in which amphotericin B might presumably be the aetiological factor.
authors: A Atahan
authors: AA
authors: Cagatay
authors: Ozer
authors: O
authors: Taranoglu
authors: Nilufer
authors: N
authors: Alpay
authors: Fatih
authors: F
authors: Tufan
authors: Asli
authors: A
authors: Karadeniz
authors: Mahir
authors: M
authors: Kapmaz
authors: Nesimi
authors: N
authors: Buyukbabani
mesh_terms: D000328:Adult; D000666:Amphotericin B / Q000009:adverse effects* / Q000627:therapeutic use; D001706:Biopsy; D005260:Female; D006801:Humans; D009181:Mycoses / Q000188:drug therapy; D012871:Skin Diseases / Q000473:pathology*; D014657:Vasculitis / Q000473:pathology*
chemical_list: D000666:Amphotericin B