title: Total synthesis of (3R,9R,10R)-panaxytriol via tandem metathesis and metallotropic [1,3]-shift as a key step.
abstract: Enyne metathesis is unique for its capacity to carry out multiple bond formation in tandem fashion. Its combined use with metallotropic [1,3]-shift allowed for the development of a novel strategy for the total synthesis of a conjugated 1,3-diyne-containing natural product (3R,9R,10R)-panaxytriol.
authors: Department of Chemistry, University of Illinois at Chicago, 845 West Taylor Street, Chicago, Illinois 60607, USA.
authors: Eun Jin
authors: EJ
authors: Cho
authors: Daesung
authors: D
authors: Lee
mesh_terms: D002384:Catalysis; D053281:Enediynes / Q000138:chemical synthesis* / Q000737:chemistry; D005233:Fatty Alcohols / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D005894:Panax / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D053281:Enediynes; D005233:Fatty Alcohols; C057682:panaxytriol