A nonspecific form of dysembryoplastic neuroepithelial tumor presenting with intractable epilepsy.
We report here an intractable epilepsy case with fairly typical clinicoradiological features of dysembryoplastic neuroepithelial tumor (DNT), which means onset of seizures at a young age accompanying a medial temporal cystic lesion enclosed in cortical dysplasia (CD). The medial cystic lesion was composed of two morphologically distinct components; one was oligo-like and the other showed some tendency toward neuronal and glial differentiation, even though they were morphologically different from a so-called specific glioneural element (SGE). Epileptiform discharges were detected not only on the medial lesion but also on the lateral inferior temporal gyrus, which was confirmed as CD. According to both histopathological and clinical features, we named the lesion a nonspecific form of DNT.
Nishida
Namiko
N
Department of Neurosurgery, Kyoto University Graduate School of Medicine, 54 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto 606-8507, Japan.
Hayase
Yoneko
Y
Mikuni
Nobuhiro
N
Enatsu
Rei
R
Hayashi
Naoki
N
Takahashi
Jun A
JA
Nakashima
Yasuaki
Y
Ikeda
Akio
A
Amano
Shigeru
S
Hashimoto
Nobuo
N
D000328:Adult; D000927:Anticonvulsants / Q000627:therapeutic use; D001932:Brain Neoplasms / Q000150:complications / Q000473:pathology* / Q000601:surgery; D004827:Epilepsy / Q000188:drug therapy / Q000209:etiology*; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008279:Magnetic Resonance Imaging; D054220:Malformations of Cortical Development / Q000150:complications / Q000473:pathology* / Q000601:surgery; D018302:Neoplasms, Neuroepithelial / Q000150:complications / Q000473:pathology* / Q000601:surgery
D000927:Anticonvulsants