Basic mechanisms of cough: current understanding and remaining questions.
Considerable effort in many laboratories has gone into describing the afferent nerve subtypes that initiate cough, and the ionic mechanisms the activation and modulation of these nerves. In this brief overview, we have attempted to summarize some of what is understood in these areas. In addition, we have tried to highlight many of the important basic questions that remain to be answered.
Lee
Min-Goo
MG
Department of Physiology, Korea University College of Medicine, Seoul, Korea.
Undem
Bradley J
BJ
D000818:Animals; D001980:Bronchi / Q000294:innervation*; D003371:Cough / Q000503:physiopathology*; D006801:Humans; D009412:Nerve Fibers / Q000378:metabolism; D009475:Neurons, Afferent / Q000502:physiology*; D012018:Reflex / Q000502:physiology*; D014132:Trachea / Q000294:innervation*