[Cytopathological features of multiple myeloma].
Although integration of laboratory data and radiological findings are required, quantity and qualitative evaluation of plasma cells in bone marrow is still useful for the diagnosis of multiple myeloma. However, there are considerable variations in morphology of myeloma and proliferation pattern among the individual patients. Therefore, it is important to recognize cytopathological features of myeloma cells for better understanding of patients' status. For example, the finding of immature plasmablastic myeloma cells predicts the poor prognosis of the patients. In the present review, we described the cytopathological features, which is useful for diagnosis and estimation of the patients' prognosis and discrimination from reactive non-tumorous plasma cells.
Takeuchi
Tamotsu
T
Department of Pathology, Kochi Medical School.
Adachi
Yoshihiro
Y
Ikezoe
Takayuki
T
Yokoyama
Akihito
A
Furihata
Mutsuo
M
Ohtsuki
Yuji
Y
D001854:Bone Marrow Cells / Q000166:cytology* / Q000473:pathology*; D002467:Cell Nucleus; D049109:Cell Proliferation; D003593:Cytoplasm; D006801:Humans; D009101:Multiple Myeloma / Q000175:diagnosis* / Q000473:pathology*; D010950:Plasma Cells / Q000145:classification / Q000166:cytology* / Q000473:pathology*; D011379:Prognosis