title: The role of double-stranded break repair in the creation of phenotypic diversity at cereal VRN1 loci.
abstract: Nonhomologous repair of double-stranded breaks, although fundamental to the maintenance of genomic integrity in all eukaryotes, has received little attention as to its evolutionary consequences in the generation and selection of phenotypic diversity. Here we document the role of illegitimate recombination in the creation of novel alleles in VRN1 orthologs selected to confer adaptation to annual cropping systems in barley and wheat.
authors: National Institute of Agricultural Botany, Cambridge CB3 0LE, United Kingdom.
authors: James
authors: J
authors: Cockram
authors: Ian J
authors: IJ
authors: Mackay
authors: Donal M
authors: DM
authors: O'Sullivan
mesh_terms: D000222:Adaptation, Physiological / Q000235:genetics*; D001483:Base Sequence; D018556:Crops, Agricultural / Q000235:genetics; D053903:DNA Breaks, Double-Stranded; D004260:DNA Repair; D004268:DNA-Binding Proteins / Q000235:genetics*; D002523:Edible Grain / Q000235:genetics*; D017343:Genes, Plant; D014644:Genetic Variation; D001467:Hordeum / Q000235:genetics; D008969:Molecular Sequence Data; D010940:Plant Proteins / Q000235:genetics; D012097:Repressor Proteins / Q000235:genetics*; D014908:Triticum / Q000235:genetics
chemical_list: D004268:DNA-Binding Proteins; D010940:Plant Proteins; D012097:Repressor Proteins