title: 2',3'-isopropylidene group, a molecular scaffold to study the activity of adenosine and adenylate deaminase on adenosine analogues modified in the ribose moiety.
abstract: 2 ',3 '-Isopropylidene group can be used as a molecular scaffold for the introduction of modifications at 5 ' and 1 ' positions of adenosine and these modified nucleosides are used to evaluate the biocatalytic activity of adenosine and adenylate deaminase.
authors: Dipartimento di Scienze Precliniche LITA Vialba, Università degli Studi di Milano, via G.B. Grassi 74, 20157 Milan, Italy. pierangela.ciuffreda@unimi.it
authors: Pierangela
authors: P
authors: Ciuffreda
authors: Laura
authors: L
authors: Alessandrini
authors: Enzo
authors: E
authors: Santaniello
mesh_terms: D000659:AMP Deaminase / Q000737:chemistry*; D000241:Adenosine / Q000031:analogs & derivatives* / Q000737:chemistry; D000243:Adenosine Deaminase / Q000737:chemistry*; D012266:Ribose / Q000737:chemistry*
chemical_list: C014626:2',3'-isopropylideneadenosine; D012266:Ribose; D000243:Adenosine Deaminase; D000659:AMP Deaminase; D000241:Adenosine