title: Inner-ear obliteration in ulcerative colitis patients with sensorineural hearing loss.
abstract: OBJECTIVE
  Systemic autoimmune diseases, including ulcerative colitis, may involve the inner ear. Several ulcerative colitis cases presenting with sensorineural hearing loss have been reported. We report the T2-weighted, three-dimensional, inner-ear magnetic resonance imaging findings in the inner ears of two such patients.
  
  
  METHODS
  Case reports and a review of the literature concerning autoimmune disease and sensorineural hearing loss are presented.
  
  
  RESULTS
  We describe two cases of ulcerative colitis with sensorineural hearing loss in which three-dimensional magnetic resonance imaging revealed obliteration of the inner ear. Those inner ears with obliteration had severe hearing loss, and responded poorly to steroid therapy.
  
  
  CONCLUSIONS
  To our knowledge, there has been no previous published report of the T2-weighted, inner-ear magnetic resonance imaging findings of cases of ulcerative colitis with sensorineural hearing loss. This paper represents the first published report in the world literature of inner-ear obliteration in such patients. Three-dimensional magnetic resonance imaging is beneficial in elucidating the pathophysiology of the inner-ear involvement seen in ulcerative colitis.
authors: Department of Otolaryngology-Head and Neck Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Shikata-cho,Okayama, Japan. skariya@cc.okayama-u.ac.jp
authors: S
authors: S
authors: Kariya
authors: K
authors: K
authors: Fukushima
authors: Y
authors: Y
authors: Kataoka
authors: S
authors: S
authors: Tominaga
authors: K
authors: K
authors: Nishizaki
mesh_terms: D003093:Colitis, Ulcerative / Q000150:complications* / Q000209:etiology; D007758:Ear, Inner / Q000473:pathology*; D005260:Female; D006319:Hearing Loss, Sensorineural / Q000276:immunology / Q000473:pathology*; D006801:Humans; D021621:Imaging, Three-Dimensional; D007759:Labyrinth Diseases / Q000209:etiology / Q000473:pathology*; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged