title: Laparoscopic enucleation of insulinomas.
abstract: OBJECTIVE
  Laparoscopic enucleation of insulinomas is safe and effective and is associated with a short hospital stay.
  
  
  METHODS
  Case series identified through retrospective review of medical records.
  
  
  METHODS
  University of California, San Francisco Medical Center, a tertiary care referral hospital.
  
  
  METHODS
  Nine patients with insulinomas that were thought to be suitable for laparoscopic enucleation.
  
  
  METHODS
  Laparoscopic enucleation of solitary insulinomas of the pancreas.
  
  
  METHODS
  Successful enucleation, conversion to open operation, postoperative complications, and duration of hospitalization.
  
  
  RESULTS
  Seven of 9 patients had curative laparoscopic enucleations of insulinomas. In the 2 other patients, the laparoscopic approach was converted to an open operation to perform a distal pancreatectomy. All patients were cured. Computed tomography (CT) localized the tumor in 5 of 9 patients; laparoscopic enucleation was successful in all 5. Endoscopic ultrasonography correctly identified the lesions in 2 of 3 patients with nondiagnostic CT scans. Both lesions were successfully enucleated laparoscopically. Postoperative pancreatic fistulas occurred in 7 of 9 patients, but they caused little morbidity. No patient required another operation. Five of 7 patients treated laparoscopically were discharged to home on the first postoperative day.
  
  
  CONCLUSIONS
  Laparoscopic enucleation was safe and effective. If the lesion was seen on CT, it could be removed laparoscopically. Endoscopic ultrasonography was useful for identifying lesions in patients whose CT scans were nondiagnostic. Pancreatic fistulas were common, but they resolved spontaneously and produced little morbidity. Laparoscopic enucleation resulted in a short hospitalization and rapid recovery for most patients.
authors: Surgical Service, Veterans Affairs Medical Center, 4150 Clement St, San Francisco, CA 94121, USA.
authors: Matthew P
authors: MP
authors: Sweet
authors: Yumi
authors: Y
authors: Izumisato
authors: Lawrence W
authors: LW
authors: Way
authors: Orlo H
authors: OH
authors: Clark
authors: Umesh
authors: U
authors: Masharani
authors: Quan-Yang
authors: QY
authors: Duh
mesh_terms: D000293:Adolescent; D000328:Adult; D005260:Female; D006801:Humans; D007340:Insulinoma / Q000601:surgery*; D010535:Laparoscopy; D008297:Male; D008875:Middle Aged; D010180:Pancreatectomy; D010190:Pancreatic Neoplasms / Q000601:surgery*