title: Huge renal cyst with parietal renal cell carcinoma, osseous metaplasia and a papillary adenoma: a case report with unique clinicopathological features and literature review.
abstract: The unique clinicopathological features of a giant solitary renal cyst with a parietal clear cell carcinoma in contiguity with a focus of osseous metaplasia and a papillary adenoma are reported. Ultrasonography and computed tomography showed a single cyst with a focal wall irregularity. During surgery, a frozen section revealed the presence of a renal cell carcinoma of clear cell type, so a nephrectomy was performed. After extensive pathological sampling of the cyst's wall, a focus of osseous metaplasia in contiguity with the main tumour and a microscopic papillary adenoma were found. Diagnostic implications for the present case are discussed within a pertinent literature review.
authors: Division of Pathology, CRO-Istituto Nazionale Tumori, Aviano, Italy. gpuppa@yahoo.com
authors: Giacomo
authors: G
authors: Puppa
authors: Andrea
authors: A
authors: Gervasio
authors: Kutsal
authors: K
authors: Yorukoglu
authors: Romano
authors: R
authors: Colombari
authors: Francesco
authors: F
authors: De Marchi
authors: Vincenzo
authors: V
authors: Canzonieri
mesh_terms: D000236:Adenoma / Q000378:metabolism / Q000473:pathology*; D002292:Carcinoma, Renal Cell / Q000378:metabolism / Q000473:pathology*; D006801:Humans; D007150:Immunohistochemistry; D053552:Keratin-7 / Q000032:analysis; D007668:Kidney / Q000737:chemistry / Q000000981:diagnostic imaging; D052177:Kidney Diseases, Cystic / Q000378:metabolism / Q000473:pathology*; D007680:Kidney Neoplasms / Q000378:metabolism / Q000473:pathology*; D008297:Male; D008679:Metaplasia; D008875:Middle Aged; D015260:Neprilysin / Q000032:analysis; D011859:Radiography; D014463:Ultrasonography
chemical_list: D053552:Keratin-7; D015260:Neprilysin