Irradiation of glomus jugulare tumors: a historical perspective.
Glomus jugulare tumors are rare, slow-growing vascular lesions that arise from the chief cells of the paraganglia within the jugular bulb. They can be associated with the tympanic branch of the glossopharyngeal nerve (Jacobsen nerve) or the auricular branch of the vagus nerve (Arnold nerve) and are also referred to as chemodectomas or nonchromaffin paragangliomas. Optimal treatment of these histologically benign tumors remains controversial. Surgery remains the treatment of choice, but can carry high morbidity rates. External-beam radiation was originally used for subtotal resections and in patients who were poor surgical candidates; however, radiosurgery has recently been introduced as an effective and safe treatment option for patients with these tumors. In this article the authors discuss the history of radiation therapy for glomus jugulare tumors, focusing on recent radiosurgical results.
Li
Gordon
G
Department of Neurosurgery, Stanford University Medical Center, Stanford, California 94305., USA. gordonli@stanford.edu
Chang
Steven
S
Adler
John R
JR
Lim
Michael
M
D005925:Glomus Jugulare Tumor / Q000532:radiotherapy* / Q000601:surgery*; D049673:History, 20th Century; D049674:History, 21st Century; D006801:Humans; D008279:Magnetic Resonance Imaging; D011829:Radiation Dosage; D016634:Radiosurgery / Q000266:history* / Q000379:methods*