Phentolamine therapy for cocaine-association acute coronary syndrome (CAACS).
BACKGROUND
The emergency department (ED) evaluation of cocaine-associated acute coronary syndrome (CAACS) is often a diagnostic and therapeutic challenge.


METHODS
We are reporting on the treatment of a patient with cocaine-associated acute coronary syndrome (CAACS) who did not benefit from standard therapy, but who eventually responded positively to phentolamine, an alpha-adrenergic receptor antagonist.


CONCLUSIONS
This report should encourage physicians to add phentolamine to their pharmacotherapeutic armamentarium in the treatment of CAACS.
Chan
Gar Ming
GM
Department of Emergency Medicine, North Shore University Hospital, New York University School of Medicine, 300 Community Drive, Manhasset, NY 10030, USA. garchan@pol.net
Sharma
Rahul
R
Price
Dennis
D
Hoffman
Robert S
RS
Nelson
Lewis S
LS
D054058:Acute Coronary Syndrome / Q000188:drug therapy*; D000317:Adrenergic alpha-Antagonists / Q000627:therapeutic use*; D000328:Adult; D003042:Cocaine / Q000506:poisoning*; D004562:Electrocardiography / Q000187:drug effects; D006801:Humans; D008297:Male; D010646:Phentolamine / Q000627:therapeutic use*
D000317:Adrenergic alpha-Antagonists; D003042:Cocaine; D010646:Phentolamine