title: Porphyrin-DNA: a supramolecular scaffold for functional molecules on the nanometre scale.
abstract: We are pursuing the aim to use DNA as a supramolecular scaffold for the creation of electronically functional molecules on the nanometre scale. Here, we give a review on our results on porphyrin modified nucleotides used for this purpose. A general synthetic route to porphyrin-nucleotides has been devised, and the building blocks can be incorporated into oligonucleotides using standard solid phase synthesis methods. Up to 11 porphyrins were incorporated into DNA, reaching a length of approximately 4 nm in the array. The spectroscopic data are consistent with a porphyrin induced secondary structure stabilisation in the single strands.
authors: Department of Chemistry, University of Basel, Basel, Switzerland.
authors: Imenne
authors: I
authors: Bouamaied
authors: Leslie-Anne
authors: LA
authors: Fendt
authors: Daniel
authors: D
authors: Häussinger
authors: Markus
authors: M
authors: Wiesner
authors: Sandra
authors: S
authors: Thöni
authors: Nicolas
authors: N
authors: Amiot
authors: Eugen
authors: E
authors: Stulz
mesh_terms: D001483:Base Sequence; D004247:DNA / Q000737:chemistry*; D049329:Nanostructures / Q000737:chemistry*; D009711:Nucleotides / Q000737:chemistry*; D011166:Porphyrins / Q000737:chemistry*
chemical_list: D009711:Nucleotides; D011166:Porphyrins; D004247:DNA