title: Increased activity on In-111 octreotide imaging due to radiation fibrosis.
abstract: Indium-111 octreotide scintigraphy is a useful investigation in the diagnosis and staging neuroendocrine or nonendocrine malignancies such as carcinoid, granulomas, small cell lung cancer, medullary thyroid carcinoma, and others. Tumors with large numbers of somatostatin receptors can be accurately imaged and this can be useful in guiding treatment. Although uncommon, false-positives studies have been reported and often the cause is unexplained but assumed to be a high number of somatostatin receptors in other pathology. We present a case with increased uptake resulting in a scan due to pulmonary fibrosis.
authors: Department of Nuclear Medicine, Nepean Hospital, Penrith, NSW, Australia.
authors: Leo
authors: L
authors: Ha
authors: Robert
authors: R
authors: Mansberg
authors: Diep
authors: D
authors: Nguyen
authors: Chuong
authors: C
authors: Bui
mesh_terms: D001943:Breast Neoplasms / Q000532:radiotherapy; D003937:Diagnosis, Differential; D005189:False Positive Reactions; D005260:Female; D006801:Humans; D008875:Middle Aged; D015282:Octreotide / Q000031:analogs & derivatives*; D017564:Radiation Pneumonitis / Q000000981:diagnostic imaging*; D019275:Radiopharmaceuticals; D014055:Tomography, Emission-Computed
chemical_list: D019275:Radiopharmaceuticals; C094279:indium-111-octreotide; D015282:Octreotide