title: Stimulant alcohol effects prime within session drinking behavior.
abstract: BACKGROUND
  Individual differences in subjective alcohol effects have been shown to differ by risk status (e.g., family history of alcoholism) and to predict future risk for alcohol-related problems. Presumably, individual differences in both stimulant and sedative responses affect the rewarding value of drinking which, in turn, impacts future drinking behavior. Although plausible, this theoretical model is largely untested.
  
  
  OBJECTIVE
  The current study attempted to provide experimental evidence for the impact of subjective alcohol responses on within session drinking behavior.
  
  
  METHODS
  Using a placebo-controlled between-subjects alcohol administration paradigm, experiences and evaluations of stimulant and sedative alcohol effects (after a target dose of 0.06 g%) were assessed as predictors of ad-libitum consumption in the context of anticipatory stress.
  
  
  RESULTS
  Analyses indicated that an initial dose of alcohol increased experiences of both stimulation and sedation although stimulant effects were evaluated much more positively. In addition, stimulant effects after a priming dose predicted further consumption, whereas sedative effects did not.
  
  
  CONCLUSIONS
  At least among moderate to heavy drinking college students, stimulant alcohol effects are more reinforcing and predict within session drinking behavior under social stress. Increased attention should be given to stimulant alcohol effects as a risk factor for excessive consumption in this population. Incorporating information about stimulant alcohol effects in prevention and intervention programs may also be important if additional research supports the current results.
authors: Department of Psychology, Yale University, 2 Hillhouse Ave, New Haven, CT 06520-8205, USA. william.corbin@yale.edu
authors: William R
authors: WR
authors: Corbin
authors: Ashley
authors: A
authors: Gearhardt
authors: Kim
authors: K
authors: Fromme
mesh_terms: D000328:Adult; D000339:Affect / Q000187:drug effects; D000428:Alcohol Drinking / Q000523:psychology*; D000704:Analysis of Variance; D002492:Central Nervous System Depressants / Q000494:pharmacology*; D000697:Central Nervous System Stimulants; D003627:Data Interpretation, Statistical; D000431:Ethanol / Q000494:pharmacology*; D005260:Female; D006801:Humans; D008297:Male; D015990:Placebo Effect; D011581:Psychological Tests; D012307:Risk Factors; D013315:Stress, Psychological / Q000523:psychology
chemical_list: D002492:Central Nervous System Depressants; D000697:Central Nervous System Stimulants; D000431:Ethanol