[Study on ABO gene polymorphism in Uighur nationality in Xinjiang of China].
OBJECTIVE
To study the distribution of ABO gene polymorphism in Uighur population in Xinjiang area of China.


METHODS
DNA was extracted from 160 Uygur unrelated donorso blood and PCR-sequence specific primer analysis was performed. Some difficult samples were further directly sequenced.


RESULTS
Six alleles were detected in a population of 160 Uighur individuals, the gene frequencies of which were 0.2062(A101), 0.0563(A102), 0.0156(A201), 0.0031(A205),0.1875(B01),0.5312(O01), respectively.


CONCLUSIONS
The characteristics for AB gene structure of Xinjiang Uighur suggests that genetic polymorphism is distinguished between Xinjiang Uighur nationality and Chinese Han nationality, and both of them have discrepancy and confluent characters.
Yu
Qiong
Q
Shenzhen Blood Center, Shenzhen Institute of Transfusion Medicine, Shenzhen, Guangdong, 518035 PR China. yuqiong7867@yahoo.com.cn
Lu
Liang
L
Yu
Miao-cheng
MC
Liang
Yan-lian
YL
Su
Yu-qing
YQ
Wang
Da-ming
DM
D000017:ABO Blood-Group System / Q000235:genetics*; D044466:Asian People / Q000235:genetics*; D001483:Base Sequence; D002681:China / Q000208:ethnology; D005006:Ethnicity; D005260:Female; D005787:Gene Frequency; D020022:Genetic Predisposition to Disease; D005838:Genotype; D006801:Humans; D008297:Male; D011110:Polymorphism, Genetic
D000017:ABO Blood-Group System