Sex-dependent neurofunctional predictors of long-term maintenance of visual word learning.
A previous study has revealed sex-dependent neurofunctional predictors of visual word learning [C. Chen, G. Xue, Q. Dong, Z. Jin, T. Li, F. Xue, L. Zhao, Y. Guo, Sex determines the neurofunctional predictors of visual word learning, Neuropsychologia 45 (2007) 741-747]. The present study aimed to extend that study to investigate sex-dependent neurofunctional predictors of long-term maintenance. Twenty-three Chinese college students trained in the previous study were followed up twice: immediately (T1) and 6 months after the training (T2). At both T1 and T2, subjects were tested with the simultaneously presented same-different judgment task. Compared with the T1 performance, subjects (both males and females) showed a small but significant amount of forgetting (i.e., longer reaction times) at T2. Consistent with our hypothesis, males' performance at both T1 and T2 was predicted by the pre-training left-lateralized fusiform activation, whereas females' performance was predicted by symmetrical bilateral fusiform activation.
Dong
Qi
Q
State Key Laboratory of Cognitive Neuroscience and Learning, Beijing Normal University, Beijing 100875, PR China. dongqi@bnu.edu.cn
Mei
Leilei
L
Xue
Gui
G
Chen
Chuansheng
C
Li
Tian
T
Xue
Feng
F
Huang
Shizhi
S
D000328:Adult; D000704:Analysis of Variance; D005260:Female; D007839:Functional Laterality; D006801:Humans; D007600:Judgment / Q000502:physiology; D008279:Magnetic Resonance Imaging; D008297:Male; D011939:Mental Recall / Q000502:physiology*; D010364:Pattern Recognition, Visual / Q000502:physiology*; D011237:Predictive Value of Tests; D011930:Reaction Time / Q000502:physiology; D012727:Sex Characteristics; D013223:Statistics as Topic; D013997:Time Factors; D014706:Verbal Learning / Q000502:physiology*