title: [Epidemiological study on 38 418 syphilis cases during pregnancy].
abstract: OBJECTIVE
  To explore the prevalence of syphilis and risk factors on pregnant women in Fujian province.
  
  
  METHODS
  From July 1st, 2004 to June 30th, 2006, epidemiologic methods as questionnaires to fill in and rapid plasma reagent testing (RPR) were performed. Pregnant women with positive RPR test and then were confirmed by treponema pallidum test (TP). Intervention was provided to the pregnant women who were followed up to the postpartum periods. Results were compared during the peri-neonatal stage between syphilis-infected and non-infected women. Factors which were relative to syphilis infection were analyzed by simple and then further logistic regression analysis.
  
  
  RESULTS
  There were 38 418 pregnant women under study, of whom 772 were confirmed including 60 who were still pregnant. The prevalence of syphilis during pregnancy was 1.85% (712/38 418), with mostly underlying syphilis which played an important role during the neonatal stage. Main risk factors to have been found as: women's occupation, cultural background, place of living, husband's occupation, family income, having sexually transmitted disease(STD) infection. The prognosis of peri-neonatal stage was worse if the mother was having blood RPR test positive. Mortality of peri-neonatal, preterm birth rate and low-birth weight rate were found also higher among mothers when RPR was positive (P < 0.01).
  
  
  CONCLUSIONS
  The prevalence of syphilis in Fujian province was going up yearly. 8 factors including women's occupation, cultural background, place of living, received poor health education, having multiple sexual partners, husband's occupation, family income and having STD were main risk factors in the province, the mother's status of syphilis infection would strongly relate to the peri-neonatal stage of pregnancy.
authors: Fujian Provincial Maternal and Children's Health Hospital, Fuzhou, China.
authors: Rong-Lian
authors: RL
authors: Zhang
authors: Lie-Ping
authors: LP
authors: Chen
authors: Qi-Yan
authors: QY
authors: Chen
authors: Xiu-Yun
authors: XY
authors: Wang
authors: Li-Ping
authors: LP
authors: Zhang
authors: Xiao-Yan
authors: XY
authors: Xiu
mesh_terms: D000328:Adult; D002681:China / Q000453:epidemiology; D005260:Female; D006801:Humans; D016015:Logistic Models; D008428:Maternal Mortality; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000453:epidemiology*; D015995:Prevalence; D012307:Risk Factors; D011795:Surveys and Questionnaires; D013587:Syphilis / Q000453:epidemiology*; D013588:Syphilis Serodiagnosis; D055815:Young Adult