Lymphocytic bronchiolitis as presenting disorder in an undiagnosed adult patient with chronic granulomatous disease.
Chronic Granulomatous Disease (CGD) is a rare primary immunodeficiency disease. Although the most affected patients are diagnosed in childhood, there are several reports of the disease presenting in adult patients. Here we present a 40 years old man who was admitted in hospital due to respiratory symptoms and ground glass pattern in high resolution computed tomography of lung. Open lung biopsy revealed lymphocytic bronchiolitis. Because of past medical history of granulomatous lesion in lung and recurrent abscesses of skin and soft tissue, NBT test was conducted which its result revealed that the disorder was compatible with CGD and then it was confirmed by fluorescent cytometry.
Tabarsi
Payam
P
National Research Institute of TB and Lung disease, Niavaran-Darabad, Massih Daneshvari Hospital, Tehran, Iran. tabarsi@nritld.ac.ir
Mirsaeidi
Mehdi
M
Karimi
Shirin
S
Banieghbal
Behzad
B
Mansouri
Nahal
N
Masjedi
Mohammad Reza
MR
Mansouri
Davood
D
D000328:Adult; D001988:Bronchiolitis / Q000150:complications* / Q000473:pathology; D006105:Granulomatous Disease, Chronic / Q000150:complications* / Q000473:pathology; D006801:Humans; D008168:Lung / Q000473:pathology*; D008214:Lymphocytes / Q000473:pathology*; D008232:Lymphoproliferative Disorders / Q000150:complications* / Q000473:pathology; D008297:Male