Primary mucinous adenocarcinoma of the bladder with signet-ring cells: case report.
BACKGROUND
Primary adenocarcinomas of the bladder are uncommon and usually occur by contiguity with or hematogenic dissemination of other adenocarcinomas such as colorectal, prostate and gynecological tract carcinomas. Mucinous and signet-ring cell histological patterns are even rarer and it is often difficult to morphologically distinguish them from metastatic colorectal adenocarcinoma.


METHODS
We present and discuss a rare case of primary mucinous adenocarcinoma of the bladder with signet-ring cells in a 57-year-old male patient. Other primary sites for the tumor had been excluded and, in the absence of digestive tract tumor and for confirmation that it was a primary bladder tumor, an immunohistochemistry study was performed.
Marques
Marcelo Lorenzi
ML
Hospital Professor Edmundo Vasconcelos, São Paulo, Brazil.
D'Alessandro
Gabriel Salum
GS
Chade
Daher Cezar
DC
Lanzoni
Valéria Pereira
VP
Saiovici
Samuel
S
Almeida
Cláudio José Ramos de
CJ
D002288:Adenocarcinoma, Mucinous / Q000175:diagnosis*; D018279:Carcinoma, Signet Ring Cell / Q000175:diagnosis*; D006801:Humans; D053554:Keratin-20 / Q000032:analysis; D053552:Keratin-7 / Q000032:analysis; D008297:Male; D008875:Middle Aged; D055262:Mucin-2; D009077:Mucins / Q000032:analysis; D013274:Stomach Neoplasms / Q000175:diagnosis; D001749:Urinary Bladder Neoplasms / Q000175:diagnosis*
D053554:Keratin-20; D053552:Keratin-7; C524625:MUC2 protein, human; D055262:Mucin-2; D009077:Mucins