A synopsis on different homologous series of fomocaine derivatives. In vitro interactions with the cytochrome P450 system, toxicity, and local anaesthetic effects in rats--part II.
Lupp
Amelie
A
Institute of Pharmacology and Toxicology, Friedrich Schiller University, Jena, Germany. Amelie.Lupp@mti.uni-jena.de
Karge
Elke
E
Dahse
Thomas
T
Glassl
Peter
P
Jung
Beate
B
Listing
Monika
M
Seeling
Andreas
A
Wange
Johannes
J
Wennek-Klose
Janett
J
Oelschläger
Herbert
H
Fleck
Christian
C
D000765:Anesthesia, Conduction; D000772:Anesthesia, Local; D000779:Anesthetics, Local / Q000138:chemical synthesis / Q000737:chemistry / Q000633:toxicity*; D000818:Animals; D002626:Chemistry, Pharmaceutical; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism*; D005079:Excipients; D007928:Lethal Dose 50; D049449:Luminescence; D006899:Mixed Function Oxygenases / Q000378:metabolism; D010243:Paralysis / Q000139:chemically induced; D010647:Phenyl Ethers / Q000138:chemical synthesis / Q000737:chemistry / Q000633:toxicity*; D051381:Rats; D012997:Solvents; D013329:Structure-Activity Relationship
D000779:Anesthetics, Local; D005079:Excipients; D010647:Phenyl Ethers; D012997:Solvents; C100275:fomocain; D003577:Cytochrome P-450 Enzyme System; D006899:Mixed Function Oxygenases