title: Microwave-assisted synthesis and antimicrobial activities of flavonoid derivatives.
abstract: Eleven flavonoid derivatives were synthesised using a modified Baker-Venkataraman rearrangement, and subsequent microwave-assisted closure of the heterocyclic ring. All of the synthetic compounds displayed antifungal activity against Aspergillus niger and Fusarium oxysporium, and two of the synthetic flavonoid analogues exhibited significant activity against methicillin-resistant Staphylococcus aureus.
authors: School of Chemistry, University of Southampton, Southampton SO17 1BJ, UK.
authors: Sherif B
authors: SB
authors: Abdel Ghani
authors: Louise
authors: L
authors: Weaver
authors: Zidan H
authors: ZH
authors: Zidan
authors: Hussein M
authors: HM
authors: Ali
authors: C William
authors: CW
authors: Keevil
authors: Richard C D
authors: RC
authors: Brown
mesh_terms: D000890:Anti-Infective Agents / Q000138:chemical synthesis* / Q000494:pharmacology*; D001234:Aspergillus niger / Q000187:drug effects; D005419:Flavonoids / Q000138:chemical synthesis* / Q000494:pharmacology*; D005670:Fusarium / Q000187:drug effects; D016106:Methicillin Resistance; D008826:Microbial Sensitivity Tests; D008872:Microwaves; D013211:Staphylococcus aureus / Q000187:drug effects
chemical_list: D000890:Anti-Infective Agents; D005419:Flavonoids