Synthesis of new heterocyclic derivatives of alpha,alpha-trehalose.
Several novel N-1, N-2, and S-5 tetrazole and 1,3,4-oxadiazole derivatives of alpha,alpha-trehalose disubstituted at C-6,6', with potential synthetic and pharmacological interest were prepared from commercial tetrazoles and 1,3,4-oxadiazoles in reaction with hexa-O-benzyl-6,6'-di-O-triflyl-alpha,alpha-trehalose.
Luduvico
Inácio
I
Departamento de Química-Instituto de Ciências Exatas, Universidade Federal de Minas Gerais, Avenida Antônio Carlos 6627, Belo Horizonte-MG, CEP 31270-901, Brazil. i.luduvico@bol.com.br
Couri
Mara R C
MR
dos Santos
Leandro J
LJ
Prado
Maria A F
MA
Gil
Rossimiriam P Freitas
RP
Alves
Rosemeire B
RB
D006571:Heterocyclic Compounds / Q000138:chemical synthesis*; D010069:Oxadiazoles; D013777:Tetrazoles; D014199:Trehalose / Q000138:chemical synthesis*
D006571:Heterocyclic Compounds; D010069:Oxadiazoles; D013777:Tetrazoles; D014199:Trehalose