title: [Case of multi-drug resistant pulmonary tuberculosis with bilateral cavitary lesions successfully treated by surgical treatment].
abstract: A case was 38 years old male. He was pointed out abnormal shadow on chest X-ray and complained respiratory infection symptoms. He had not past history of tuberculosis. He was diagnosed as multi-drug resistant tuberculosis (MDR-TB) in a certain hospital and was referred to our hospital to undergo treatment. His drug sensitivity test by Ogawa medium was resistant to all anti-tuberculosis drugs except for kanamycin (KM) and enviomycin (EVM). His chest X-ray revealed large cavities in the right upper field and infiltrations in the right lower field and small cavitary lesions in the left lower field. The right pneumonectomy was done because he took anti-tuberculosis drugs but his sputum examinations continued to be smear and culture positive without improvement of the lesions. After the surgical treatment (right pneumonectomy), he continued anti-tuberculosis drugs therapy and the chest X-ray improved including the collapse of left lower cavitary lesions. This case was a difficult case to treat because of bilateral cavitary lesions. However he was successfully treated by the surgical treatment.
authors: Department of Respiratory Medicine, Fukujuji Hospital, Tokyo, Japan. okumuram@fukujuji.org
authors: Masao
authors: M
authors: Okumura
authors: Hideo
authors: H
authors: Ogata
authors: Takashi
authors: T
authors: Yoshiyama
authors: Hiroyuki
authors: H
authors: Kokutoh
authors: Eiji
authors: E
authors: Tadokoro
authors: Motoko
authors: M
authors: Kubota
authors: Masako
authors: M
authors: Ueyama
authors: Masako
authors: M
authors: Wada
authors: Yutsuki
authors: Y
authors: Nakajima
mesh_terms: D000328:Adult; D000904:Antibiotics, Antitubercular / Q000494:pharmacology / Q000627:therapeutic use; D018432:Drug Resistance, Multiple; D006801:Humans; D008297:Male; D009169:Mycobacterium tuberculosis / Q000187:drug effects* / Q000302:isolation & purification; D011013:Pneumonectomy; D013183:Sputum / Q000382:microbiology; D016896:Treatment Outcome; D014397:Tuberculosis, Pulmonary / Q000175:diagnosis / Q000382:microbiology / Q000601:surgery*
chemical_list: D000904:Antibiotics, Antitubercular