title: Vaccination in Brazilian HIV-infected adults: a cross-sectional study.
abstract: HIV-infected patients are at risk for vaccine-preventable infections. The Brazilian National Immunization Program provided recommendations for this population. However, the vaccine coverage reached by this program is unknown. This study aimed at evaluating the vaccine coverage of HIV-infected adults followed at Hospital das Clínicas, University of São Paulo School of Medicine. Data were collected on age, gender, mode of HIV transmission, Centers for Disease Classification 1993 classification (CDC/93), antiretrovirals, CD4 count, HIV viral load, and immunization charts, from April 2003 to August 2004. We interviewed 144 randomly selected patients, 74% male; mean age, 39.95 years; CDC classification: A, 40.6%; B, 19.6%; and C, 39.9%. Most of patients were undergoing highly active antiretroviral therapy (HAART; 86.8%). Mean CD4 count 442.6 cells/mm3. Viral load less than 400 copies per milliliter in 59.4% of patients. Only 36.1% of patients were adequately immunized for diphtheria/tetanus, 54.9% for pneumococcus, 24.3% for flu, and 76.9% for hepatitis B. In relation to live attenuated vaccines, 5 patients received measles, mumps, and rubella vaccine and 7 patients yellow fever vaccine. Two patients were vaccinated against yellow fever despite CD4 less than 200 cell/mm3. We verified poor vaccine coverage in HIV-infected patients. Vaccination campaigns and incorporation of vaccine rooms in sexually transmitted disease (STD)/AIDS clinics could improve this situation.
authors: Service of Extension for the Treatment of HIV/AIDS Patients "Casada AIDS," Hospital das Clínicas, University of São Paulo School of Medicine, Brazil.
authors: Yeh Li
authors: YL
authors: Ho
authors: Thatiana
authors: T
authors: Enohata
authors: Marta Heloisa
authors: MH
authors: Lopes
authors: Sigrid
authors: S
authors: De Sousa Dos Santos
mesh_terms: D000328:Adult; D000368:Aged; D023241:Antiretroviral Therapy, Highly Active; D001424:Bacterial Infections / Q000517:prevention & control*; D001428:Bacterial Vaccines / Q000008:administration & dosage*; D001938:Brazil; D003430:Cross-Sectional Studies; D005260:Female; D015658:HIV Infections / Q000150:complications* / Q000188:drug therapy; D006801:Humans; D017589:Immunization Programs; D008297:Male; D008875:Middle Aged; D009313:National Health Programs; D014611:Vaccination / Q000706:statistics & numerical data*; D014765:Viral Vaccines / Q000008:administration & dosage*; D014777:Virus Diseases / Q000517:prevention & control* / Q000821:virology
chemical_list: D001428:Bacterial Vaccines; D014765:Viral Vaccines