A perspective on the use of concentration-QT modeling in drug development.
Russell
Tanya
T
Clinical Pharmacology, Pfizer Global Research and Development, Eastern Point Road, Groton, CT 06340, USA.
Riley
Steven P
SP
Cook
Jack A
JA
Lalonde
Richard L
RL
D004305:Dose-Response Relationship, Drug; D015507:Drugs, Investigational / Q000009:adverse effects*; D017408:Guidelines as Topic; D006801:Humans; D008133:Long QT Syndrome / Q000139:chemically induced* / Q000175:diagnosis; D018570:Risk Assessment / Q000379:methods
D015507:Drugs, Investigational