Weed growth inhibitors from Aspergillus fischeri TISTR 3272.
Chloroform and ethyl acetate extracts of Aspergillus fischeri TISTR 3272 showed good growth inhibitory activity on Mimosa pigra and Echinochloa crus-galli. Bioassay-directed fractionation of the active extracts led to the isolation of five known compounds, (+)-terrein (1), (-)-6-hydroxymellein (2), two diketopiperazines (cyclo-(S-Pro-S-Leu) (3) and cyclo-(S-Pro-S-Val) (4)) and butyrolactone I (5). Compounds 2-5 were reported for the first time in this fungus. Their structural determinations were based on analyses of spectroscopic data and their weed growth inhibitory effects were assessed.
Phattanawasin
P
P
Faculty of Pharmacy, Silpakorn University, Nakhon Pathom 73000, Thailand. panadda@email.pharm.su.ac.th
Pojchanakom
K
K
Sotanaphun
U
U
Piyapolrungroj
N
N
Zungsontiporn
S
S
D015107:4-Butyrolactone / Q000031:analogs & derivatives / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D001230:Aspergillus / Q000737:chemistry*; D003517:Cyclopentanes / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D054659:Diketopiperazines / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D031747:Echinochloa / Q000187:drug effects* / Q000254:growth & development; D006540:Herbicides / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D049934:Isocoumarins / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D031298:Mimosa / Q000187:drug effects* / Q000254:growth & development; D015394:Molecular Structure; D009793:Ochratoxins / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D010456:Peptides, Cyclic / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology
D003517:Cyclopentanes; D054659:Diketopiperazines; D006540:Herbicides; D049934:Isocoumarins; D009793:Ochratoxins; D010456:Peptides, Cyclic; C439087:terrein; C082868:butyrolactone I; D015107:4-Butyrolactone; C120538:ochracin