Ligand design for the improvement of stability of metal complex.protein hybrids.
We have succeeded in improving the stability of Fe(Schiff-base).heme oxygenase (HO) hybrids by ligand design based on the crystal structure of Fe(N,N'-bis(salicylidene)-3.4-diaminobenzene propionic acid).HO.
Yokoi
Norihiko
N
Department of Chemistry, Graduate School of Science, Nagoya University, Furo-cho, Chikusa-ku, Nagoya, 464-8602, Japan.
Ueno
Takafumi
T
Unno
Masaki
M
Matsui
Toshitaka
T
Ikeda-Saito
Masao
M
Watanabe
Yoshihito
Y
D002857:Chromium / Q000737:chemistry*; D002942:Circular Dichroism; D018360:Crystallography, X-Ray; D006419:Heme Oxygenase (Decyclizing) / Q000737:chemistry*; D007501:Iron / Q000737:chemistry*; D008024:Ligands; D008958:Models, Molecular; D015394:Molecular Structure; D011485:Protein Binding; D011489:Protein Denaturation; D013696:Temperature
D008024:Ligands; D002857:Chromium; D007501:Iron; D006419:Heme Oxygenase (Decyclizing)