title: Translating basic science to improve pharmacotherapy for nicotine dependence.
abstract: Nicotine dependence has a complex multifactorial etiology, underscoring the value of applying a transdisciplinary research model. The important goal of treating nicotine dependence can be realized by transdisciplinary research that translates discoveries in basic neuroscience, pharmacology, genetics, and behavioral science to develop new treatment models that can be translated readily into the clinic and community. As part of this special issue highlighting work at the Transdisciplinary Tobacco Use Research Centers (TTURCs), we describe transdisciplinary research at the University of Pennsylvania TTURC aimed at elucidating the neurobiological and genetic basis of nicotine dependence, the development of novel medications, and the translation of this research to practice.
authors: University of Pennsylvania, Philadelphia, Pennsylvania, USA.
authors: Jennifer M
authors: JM
authors: Phillips
authors: Steven J
authors: SJ
authors: Siegel
authors: Alexandra E
authors: AE
authors: Shields
authors: Freda
authors: F
authors: Patterson
authors: Thomas J
authors: TJ
authors: Gould
authors: Andrew A
authors: AA
authors: Strasser
authors: Riju
authors: R
authors: Ray
authors: Angela
authors: A
authors: Pinto
authors: Janet
authors: J
authors: Audrain-McGovern
authors: Margaret
authors: M
authors: Rukstalis
authors: Kenneth A
authors: KA
authors: Perkins
authors: Julie A
authors: JA
authors: Blendy
authors: Caryn
authors: C
authors: Lerman
mesh_terms: D006801:Humans; D012106:Research; D014029:Tobacco Use Disorder / Q000188:drug therapy*