title: The H-Invitational Database (H-InvDB), a comprehensive annotation resource for human genes and transcripts.
abstract: Here we report the new features and improvements in our latest release of the H-Invitational Database (H-InvDB; http://www.h-invitational.jp/), a comprehensive annotation resource for human genes and transcripts. H-InvDB, originally developed as an integrated database of the human transcriptome based on extensive annotation of large sets of full-length cDNA (FLcDNA) clones, now provides annotation for 120 558 human mRNAs extracted from the International Nucleotide Sequence Databases (INSD), in addition to 54 978 human FLcDNAs, in the latest release H-InvDB_4.6. We mapped those human transcripts onto the human genome sequences (NCBI build 36.1) and determined 34 699 human gene clusters, which could define 34 057 (98.1%) protein-coding and 642 (1.9%) non-protein-coding loci; 858 (2.5%) transcribed loci overlapped with predicted pseudogenes. For all these transcripts and genes, we provide comprehensive annotation including gene structures, gene functions, alternative splicing variants, functional non-protein-coding RNAs, functional domains, predicted sub cellular localizations, metabolic pathways, predictions of protein 3D structure, mapping of SNPs and microsatellite repeat motifs, co-localization with orphan diseases, gene expression profiles, orthologous genes, protein-protein interactions (PPI) and annotation for gene families. The current H-InvDB annotation resources consist of two main views: Transcript view and Locus view and eight sub-databases: the DiseaseInfo Viewer, H-ANGEL, the Clustering Viewer, G-integra, the TOPO Viewer, Evola, the PPI view and the Gene family/group.
authors: Japan Biological Information Research Center, Japan Biological Informatics Consortium, Japan.
authors: Chisato
authors: C
authors: Yamasaki
authors: Katsuhiko
authors: K
authors: Murakami
authors: Yasuyuki
authors: Y
authors: Fujii
authors: Yoshiharu
authors: Y
authors: Sato
authors: Erimi
authors: E
authors: Harada
authors: Jun-ichi
authors: J
authors: Takeda
authors: Takayuki
authors: T
authors: Taniya
authors: Ryuichi
authors: R
authors: Sakate
authors: Shingo
authors: S
authors: Kikugawa
authors: Makoto
authors: M
authors: Shimada
authors: Motohiko
authors: M
authors: Tanino
authors: Kanako O
authors: KO
authors: Koyanagi
authors: Roberto A
authors: RA
authors: Barrero
authors: Craig
authors: C
authors: Gough
authors: Hong-Woo
authors: HW
authors: Chun
authors: Takuya
authors: T
authors: Habara
authors: Hideki
authors: H
authors: Hanaoka
authors: Yosuke
authors: Y
authors: Hayakawa
authors: Phillip B
authors: PB
authors: Hilton
authors: Yayoi
authors: Y
authors: Kaneko
authors: Masako
authors: M
authors: Kanno
authors: Yoshihiro
authors: Y
authors: Kawahara
authors: Toshiyuki
authors: T
authors: Kawamura
authors: Akihiro
authors: A
authors: Matsuya
authors: Naoki
authors: N
authors: Nagata
authors: Kensaku
authors: K
authors: Nishikata
authors: Akiko Ogura
authors: AO
authors: Noda
authors: Shin
authors: S
authors: Nurimoto
authors: Naomi
authors: N
authors: Saichi
authors: Hiroaki
authors: H
authors: Sakai
authors: Ryoko
authors: R
authors: Sanbonmatsu
authors: Rie
authors: R
authors: Shiba
authors: Mami
authors: M
authors: Suzuki
authors: Kazuhiko
authors: K
authors: Takabayashi
authors: Aiko
authors: A
authors: Takahashi
authors: Takuro
authors: T
authors: Tamura
authors: Masayuki
authors: M
authors: Tanaka
authors: Susumu
authors: S
authors: Tanaka
authors: Fusano
authors: F
authors: Todokoro
authors: Kaori
authors: K
authors: Yamaguchi
authors: Naoyuki
authors: N
authors: Yamamoto
authors: Toshihisa
authors: T
authors: Okido
authors: Jun
authors: J
authors: Mashima
authors: Aki
authors: A
authors: Hashizume
authors: Lihua
authors: L
authors: Jin
authors: Kyung-Bum
authors: KB
authors: Lee
authors: Yi-Chueh
authors: YC
authors: Lin
authors: Asami
authors: A
authors: Nozaki
authors: Katsunaga
authors: K
authors: Sakai
authors: Masahito
authors: M
authors: Tada
authors: Satoru
authors: S
authors: Miyazaki
authors: Takashi
authors: T
authors: Makino
authors: Hajime
authors: H
authors: Ohyanagi
authors: Naoki
authors: N
authors: Osato
authors: Nobuhiko
authors: N
authors: Tanaka
authors: Yoshiyuki
authors: Y
authors: Suzuki
authors: Kazuho
authors: K
authors: Ikeo
authors: Naruya
authors: N
authors: Saitou
authors: Hideaki
authors: H
authors: Sugawara
authors: Claire
authors: C
authors: O'Donovan
authors: Tamara
authors: T
authors: Kulikova
authors: Eleanor
authors: E
authors: Whitfield
authors: Brian
authors: B
authors: Halligan
authors: Mary
authors: M
authors: Shimoyama
authors: Simon
authors: S
authors: Twigger
authors: Kei
authors: K
authors: Yura
authors: Kouichi
authors: K
authors: Kimura
authors: Tomohiro
authors: T
authors: Yasuda
authors: Tetsuo
authors: T
authors: Nishikawa
authors: Yutaka
authors: Y
authors: Akiyama
authors: Chie
authors: C
authors: Motono
authors: Yuri
authors: Y
authors: Mukai
authors: Hideki
authors: H
authors: Nagasaki
authors: Makiko
authors: M
authors: Suwa
authors: Paul
authors: P
authors: Horton
authors: Reiko
authors: R
authors: Kikuno
authors: Osamu
authors: O
authors: Ohara
authors: Doron
authors: D
authors: Lancet
authors: Eric
authors: E
authors: Eveno
authors: Esther
authors: E
authors: Graudens
authors: Sandrine
authors: S
authors: Imbeaud
authors: Marie Anne
authors: MA
authors: Debily
authors: Yoshihide
authors: Y
authors: Hayashizaki
authors: Clara
authors: C
authors: Amid
authors: Michael
authors: M
authors: Han
authors: Andreas
authors: A
authors: Osanger
authors: Toshinori
authors: T
authors: Endo
authors: Michael A
authors: MA
authors: Thomas
authors: Mika
authors: M
authors: Hirakawa
authors: Wojciech
authors: W
authors: Makalowski
authors: Mitsuteru
authors: M
authors: Nakao
authors: Nam-Soon
authors: NS
authors: Kim
authors: Hyang-Sook
authors: HS
authors: Yoo
authors: Sandro J
authors: SJ
authors: De Souza
authors: Maria de Fatima
authors: Mde F
authors: Bonaldo
authors: Yoshihito
authors: Y
authors: Niimura
authors: Vladimir
authors: V
authors: Kuryshev
authors: Ingo
authors: I
authors: Schupp
authors: Stefan
authors: S
authors: Wiemann
authors: Matthew
authors: M
authors: Bellgard
authors: Masafumi
authors: M
authors: Shionyu
authors: Libin
authors: L
authors: Jia
authors: Danielle
authors: D
authors: Thierry-Mieg
authors: Jean
authors: J
authors: Thierry-Mieg
authors: Lukas
authors: L
authors: Wagner
authors: Qinghua
authors: Q
authors: Zhang
authors: Mitiko
authors: M
authors: Go
authors: Shinsei
authors: S
authors: Minoshima
authors: Masafumi
authors: M
authors: Ohtsubo
authors: Kousuke
authors: K
authors: Hanada
authors: Peter
authors: P
authors: Tonellato
authors: Takao
authors: T
authors: Isogai
authors: Ji
authors: J
authors: Zhang
authors: Boris
authors: B
authors: Lenhard
authors: Sangsoo
authors: S
authors: Kim
authors: Zhu
authors: Z
authors: Chen
authors: Ursula
authors: U
authors: Hinz
authors: Anne
authors: A
authors: Estreicher
authors: Kenta
authors: K
authors: Nakai
authors: Izabela
authors: I
authors: Makalowska
authors: Winston
authors: W
authors: Hide
authors: Nicola
authors: N
authors: Tiffin
authors: Laurens
authors: L
authors: Wilming
authors: Ranajit
authors: R
authors: Chakraborty
authors: Marcelo Bento
authors: MB
authors: Soares
authors: Maria Luisa
authors: ML
authors: Chiusano
authors: Yutaka
authors: Y
authors: Suzuki
authors: Charles
authors: C
authors: Auffray
authors: Yumi
authors: Y
authors: Yamaguchi-Kabata
authors: Takeshi
authors: T
authors: Itoh
authors: Teruyoshi
authors: T
authors: Hishiki
authors: Satoshi
authors: S
authors: Fukuchi
authors: Ken
authors: K
authors: Nishikawa
authors: Sumio
authors: S
authors: Sugano
authors: Nobuo
authors: N
authors: Nomura
authors: Yoshio
authors: Y
authors: Tateno
authors: Tadashi
authors: T
authors: Imanishi
authors: Takashi
authors: T
authors: Gojobori
mesh_terms: D000818:Animals; D002874:Chromosome Mapping; D018076:DNA, Complementary / Q000737:chemistry; D030541:Databases, Genetic; D005796:Genes; D006801:Humans; D020407:Internet; D011506:Proteins / Q000737:chemistry / Q000235:genetics / Q000378:metabolism; D012333:RNA, Messenger / Q000737:chemistry* / Q000235:genetics; D014584:User-Computer Interface
chemical_list: D018076:DNA, Complementary; D011506:Proteins; D012333:RNA, Messenger