title: Live-imaging stem-cell homeostasis in the Arabidopsis shoot apex.
abstract: A precise spatio-temporal regulation of growth and differentiation is crucial to maintain a stable population of stem cells in the shoot apical meristems (SAMs) of higher plants. The real-time and simultaneous observations of dynamics of cell identity transitions, growth patterns, and signaling machinery involved in cell-cell communication is crucial to gain a mechanistic view of stem-cell homeostasis. In this article, I review recent advances in understanding the regulatory dynamics of stem-cell maintenance in Arabidopsis thaliana and discuss future challenges involved in transforming the static maps of genetic interactions into a dynamic framework representing functional molecular and cellular interactions in living SAMs.
authors: 2150 Batchelor Hall, Department of Botany and Plant Sciences, University of California, Riverside, CA 92521, United States. venug@ucr.edu
authors: G Venugopala
authors: GV
authors: Reddy
mesh_terms: D017360:Arabidopsis / Q000235:genetics / Q000254:growth & development* / Q000378:metabolism; D029681:Arabidopsis Proteins / Q000378:metabolism; D002450:Cell Communication / Q000502:physiology; D017930:Genes, Reporter; D049452:Green Fluorescent Proteins / Q000378:metabolism; D018398:Homeodomain Proteins / Q000378:metabolism; D006706:Homeostasis / Q000502:physiology*; D018519:Meristem / Q000502:physiology*; D008954:Models, Biological; D018520:Plant Shoots / Q000502:physiology; D017434:Protein Structure, Tertiary
chemical_list: D029681:Arabidopsis Proteins; D018398:Homeodomain Proteins; C116421:WUSCHEL protein, Arabidopsis; D049452:Green Fluorescent Proteins