Single particle X-ray diffractive imaging.
In nanotechnology, strategies for the creation and manipulation of nanoparticles in the gas phase are critically important for surface modification and substrate-free characterization. Recent coherent diffractive imaging with intense femtosecond X-ray pulses has verified the capability of single-shot imaging of nanoscale objects at suboptical resolutions beyond the radiation-induced damage threshold. By intercepting electrospray-generated particles with a single 15 femtosecond soft-X-ray pulse, we demonstrate diffractive imaging of a nanoscale specimen in free flight for the first time, an important step toward imaging uncrystallized biomolecules.
Bogan
Michael J
MJ
Lawrence Livermore National Laboratory, 7000 East Avenue, Livermore, California 94550, USA. bogan2@llnl.gov
Benner
W Henry
WH
Boutet
Sébastien
S
Rohner
Urs
U
Frank
Matthias
M
Barty
Anton
A
Seibert
M Marvin
MM
Maia
Filipe
F
Marchesini
Stefano
S
Bajt
Sasa
S
Woods
Bruce
B
Riot
Vincent
V
Hau-Riege
Stefan P
SP
Svenda
Martin
M
Marklund
Erik
E
Spiller
Eberhard
E
Hajdu
Janos
J
Chapman
Henry N
HN