title: Detection of quantitative trait loci for reproduction and production traits in Large White and French Landrace pig populations.
abstract: A genome-wide scan was performed in Large White and French Landrace pig populations in order to identify QTL affecting reproduction and production traits. The experiment was based on a granddaughter design, including five Large White and three French Landrace half-sib families identified in the French porcine national database. A total of 239 animals (166 sons and 73 daughters of the eight male founders) distributed in eight families were genotyped for 144 microsatellite markers. The design included 51 262 animals recorded for production traits, and 53 205 litter size records were considered. Three production and three reproduction traits were analysed: average backfat thickness (US_M) and live weight (LWGT) at the end of the on-farm test, age of candidates adjusted at 100 kg live weight, total number of piglets born per litter, and numbers of stillborn (STILLp) and born alive (LIVp) piglets per litter. Ten QTL with medium to large effects were detected at a chromosome-wide significance level of 5% affecting traits US_M (on SSC2, SSC3 and SSC17), LWGT (on SSC4), STILLp (on SSC6, SSC11 and SSC14) and LIVp (on SSC7, SSC16 and SSC18). The number of heterozygous male founders varied from 1 to 3 depending on the QTL.
authors: INRA UR337 Station de génétique quantitative et appliquée, 78352 Jouy-en-Josas, France. thierry.tribout@jouy.inra.fr
authors: Thierry
authors: T
authors: Tribout
authors: Nathalie
authors: N
authors: Iannuccelli
authors: Tom
authors: T
authors: Druet
authors: Hélène
authors: H
authors: Gilbert
authors: Juliette
authors: J
authors: Riquet
authors: Ronan
authors: R
authors: Gueblez
authors: Marie-José
authors: MJ
authors: Mercat
authors: Jean-Pierre
authors: JP
authors: Bidanel
authors: Denis
authors: D
authors: Milan
authors: Pascale
authors: P
authors: Le Roy
mesh_terms: D000818:Animals; D001835:Body Weight / Q000235:genetics; D002874:Chromosome Mapping; D004526:Efficiency; D005260:Female; D005819:Genetic Markers / Q000502:physiology; D005838:Genotype; D008098:Litter Size / Q000235:genetics; D008297:Male; D040641:Quantitative Trait Loci; D012098:Reproduction / Q000235:genetics*; D013552:Swine / Q000235:genetics*
chemical_list: D005819:Genetic Markers