An asymmetric S(N)Ar reaction using the molecular chirality in a crystal.
An asymmetric S(N)Ar reaction was performed by using molecular chirality generated and amplified by the spontaneous crystallization of achiral naphthamides; the chirality was retained in a cold solution, caused by slow racemization, and was transferred to stable axially chiral materials with high enantiomeric excesses.
Sakamoto
Masami
M
Department of Applied Chemistry and Biotechnology, Graduate School of Engineering, Chiba University, Yayoi-cho, Inage-ku, Chiba 263-8522, Japan. sakamotom@faculty.chiba-u.jp
Unosawa
Atsushi
A
Kobaru
Shuichiro
S
Fujita
Kazuyuki
K
Mino
Takashi
T
Fujita
Tsutomu
T