Electrocardiography-triggered high-resolution CT for reducing cardiac motion artifact: evaluation of the extent of ground-glass attenuation in patients with idiopathic pulmonary fibrosis.
OBJECTIVE
The aim of this study was to evaluate the decreasing of cardiac motion artifact and whether the extent of ground-glass attenuation of idiopathic pulmonary fibrosis (IPF) was accurately assessed by electrocardiography (ECG)-triggered high-resolution computed tomography (HRCT) by 0.5-s/rotation multidetector-row CT (MDCT).


METHODS
ECG-triggered HRCT were scanned at the end-diastolic phase by a MDCT scanner with the following scan parameters; axial four-slice mode, 0.5 mm collimation, 0.5-s/rotation, 120 kVp, 200 mA/rotation, high-frequency algorithm, and half reconstruction. In 42 patients with IPF, both conventional HRCT (ECG gating(-), full reconstruction) and ECG-triggered HRCT were performed at the same levels (10-mm intervals) with the above scan parameters. The correlation between percent diffusion of carbon monoxide of the lung (%DLCO) and the mean extent of ground-glass attenuation on both conventional HRCT and ECG-triggered HRCT was evaluated with the Spearman rank correlation coefficient test.


RESULTS
The correlation between %DLCO and the mean extent of ground-glass attenuation on ECG-triggered HRCT (observer A: r = -0.790, P < 0.0001; observer B: r = -0.710, P < 0.0001) was superior to that on conventional HRCT (observer A: r = -0.395, P < 0.05; observer B: r = -0.577, P = 0.002) for both observers.


CONCLUSIONS
ECG-triggered HRCT by 0.5 s/rotation MDCT can reduce the cardiac motion artifact and is useful for evaluating the extent of ground-glass attenuation of IPF.
Nishiura
Motoko
M
Division of Health Science, Osaka University Graduate School of Medicine, Suita, Japan. nishiura@butsuryo.ac.jp
Johkoh
Takeshi
T
Yamamoto
Shuji
S
Honda
Osamu
O
Kozuka
Takenori
T
Koyama
Mitsuhiro
M
Tomiyama
Noriyuki
N
Hamada
Seiki
S
Murakami
Takamichi
T
Matsumoto
Takashi
T
Narumi
Yoshifumi
Y
Nakamura
Hironobu
H
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000465:Algorithms; D016477:Artifacts; D004562:Electrocardiography; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011658:Pulmonary Fibrosis / Q000000981:diagnostic imaging*; D014057:Tomography, X-Ray Computed / Q000379:methods*