title: A case of a ewing sarcoma family tumor in the urinary bladder after treatment for acute lymphoblastic leukemia.
abstract: We report the first case of a tumor of the Ewing sarcoma family of tumors arising from the urinary bladder 3 years after chemotherapy for acute lymphoblastic leukemia. A 16-year-old boy complained of macrohematuria and dysuria during the posttreatment follow up of his acute lymphoblastic leukemia. Ultrasonography and computed tomography revealed a 1-cm sized intravesical tumor. The tumor was transurethrally resected with no residual tumor at the margin. Histopathologic analyses revealed a small round blue cell tumor with positive staining for CD99 antibody. EWS-FLI1 fusion transcripts were detected in the tumor tissue by reverse transcriptase polymerase chain reaction. These findings support the diagnosis of Ewing sarcoma family of tumor. After adjuvant multidrug chemotherapy, the patient has shown no evidence of disease for more than 2 years.
authors: Department of Pediatrics, Kyoto Prefectural University of Medicine, Kyoto, Japan.
authors: Shinya
authors: S
authors: Osone
authors: Hajime
authors: H
authors: Hosoi
authors: Kazushi
authors: K
authors: Tanaka
authors: Kunihiko
authors: K
authors: Tsuchiya
authors: Tomoko
authors: T
authors: Iehara
authors: Akira
authors: A
authors: Morimoto
authors: Tetsuo
authors: T
authors: Hashida
authors: Masuo
authors: M
authors: Yamashita
authors: Kenji
authors: K
authors: Kawabata
authors: Koichi
authors: K
authors: Nishijo
authors: Junya
authors: J
authors: Toguchida
authors: Jun-Ichi
authors: J
authors: Hata
authors: Tohru
authors: T
authors: Sugimoto
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002648:Child; D003131:Combined Modality Therapy; D006801:Humans; D008297:Male; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000188:drug therapy*; D012512:Sarcoma, Ewing / Q000188:drug therapy / Q000601:surgery*; D016896:Treatment Outcome; D001749:Urinary Bladder Neoplasms / Q000188:drug therapy / Q000601:surgery*