title: Combined hepatocellular carcinoma and cholangiocarcinoma: a case report and review of the literature.
abstract: BACKGROUND
  Combined hepatocellular carcinoma and cholangiocarcinoma (cHCC-CC) is a rare histopathologic form of primary liver cancer. We report a case of cHCC-CC and review the literature.
  
  
  METHODS
  The clinicopathological features of a 61-year-old male were retrospectively analyzed.
  
  
  RESULTS
  Hepatocellular carcinoma (HCC) was preoperatively considered on the basis of clinical findings resembling those associated with HCC. Hepatectomy was therefore performed. Microscopically, the specimen displayed histological features of cHCC-CC. The patient has remained alive after follow-up for 3 months without evidence of recurrence and metastasis.
  
  
  CONCLUSIONS
  It is difficult to make a correct preoperative diagnosis of cHCC-CC and hepatic resection is the treatment of choice.
authors: Department of Special Treatment, Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai 200438, China. zhouyms@yahoo.com.cn
authors: Yan-Ming
authors: YM
authors: Zhou
authors: Jia-Mei
authors: JM
authors: Yang
authors: Bin
authors: B
authors: Wang
authors: Feng
authors: F
authors: Xu
authors: Ying
authors: Y
authors: Tong
authors: Dian-Qi
authors: DQ
authors: Li
mesh_terms: D001650:Bile Duct Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000628:therapy; D001653:Bile Ducts, Intrahepatic; D006528:Carcinoma, Hepatocellular / Q000000981:diagnostic imaging / Q000473:pathology* / Q000628:therapy; D018281:Cholangiocarcinoma / Q000000981:diagnostic imaging / Q000473:pathology* / Q000628:therapy; D006801:Humans; D008113:Liver Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000628:therapy; D008297:Male; D008875:Middle Aged; D014057:Tomography, X-Ray Computed