title: Early impairment of gut function and gut flora supporting a role for alteration of gastrointestinal mucosa in human immunodeficiency virus pathogenesis.
abstract: Our results show that impairment of the gastrointestinal tracts in human immunodeficiency virus (HIV)-positive patients is present in the early phases of HIV disease. This impairment is associated with alterations in gut microbiota and intestinal inflammatory parameters. These findings support the hypothesis that alterations at the gastrointestinal-tract level are a key factor in HIV pathogenesis.
authors: Division of Infectious Diseases, Department of Internal Medicine, San Gerardo Hospital, University of Milano-Bicocca, Via Solferino 16-20052, Milan, Italy. andrea.gori@unimib.it
authors: Andrea
authors: A
authors: Gori
authors: Camilla
authors: C
authors: Tincati
authors: Giuliano
authors: G
authors: Rizzardini
authors: Carlo
authors: C
authors: Torti
authors: Tiziana
authors: T
authors: Quirino
authors: Monique
authors: M
authors: Haarman
authors: Kaouther
authors: K
authors: Ben Amor
authors: Jacqueline
authors: J
authors: van Schaik
authors: Aldwin
authors: A
authors: Vriesema
authors: Jan
authors: J
authors: Knol
authors: Giulia
authors: G
authors: Marchetti
authors: Gjalt
authors: G
authors: Welling
authors: Mario
authors: M
authors: Clerici
mesh_terms: D005243:Feces / Q000737:chemistry / Q000382:microbiology; D041981:Gastrointestinal Tract / Q000276:immunology / Q000382:microbiology* / Q000473:pathology*; D006678:HIV / Q000502:physiology; D015658:HIV Infections / Q000150:complications*; D006801:Humans; D007249:Inflammation / Q000276:immunology / Q000382:microbiology / Q000473:pathology*; D007413:Intestinal Mucosa / Q000276:immunology / Q000473:pathology* / Q000503:physiopathology*; D039841:Leukocyte L1 Antigen Complex / Q000032:analysis
chemical_list: D039841:Leukocyte L1 Antigen Complex