Quantification of polychlorinated dibenzo-p-dioxins and dibenzofurans by direct injection of sample extract into the comprehensive multidimensional gas chromatograph/high-resolution time-of-flight mass spectrometer.
Polychlorinated dibenzo-p-dioxins and dibenzofurans in crude extracts of fly ash and flue gas from municipal waste incinerators were quantified using a comprehensive multidimensional gas chromatograph (GC x GC) coupled to a high-resolution time-of-flight mass spectrometer (HR-TOFMS). For identification and quantification, we developed our own program to prepare 3D chromatograms of selected mass numbers from the data of the GC x GC/HR-TOFMS. Isolation of all congeners with a TCDD toxic equivalency factor from the other isomers by only one injection was confirmed. The instrumental detection limit of TCDD on the GC x GC/HR-TOFMS was 0.9 pg by the relative calibration method. Quantification of these substances in the crude extracts was achieved by direct injection to the GC x GC/HR-TOFMS. The results agree with the values obtained using a generic gas chromatography/high-resolution mass spectrometry (GC/HRMS) system. It was confirmed that measurement by high-resolution TOFMS and GC x GC effectively reduces interference from other chemicals.
Shunji
Hashimoto
H
National Institute for Environmental Studies, 16-2 Onogawa, Tsukuba, Ibaraki 305-8506, Japan.
Yoshikatsu
Takazawa
T
Akihiro
Fushimi
F
Hiroyasu
Ito
I
Kiyoshi
Tanabe
T
Yasuyuki
Shibata
S
Masa-aki
Ubukata
U
Akihiko
Kusai
K
Kazuo
Tanaka
T
Hideyuki
Otsuka
O
Katsunori
Anezaki
A
D001572:Benzofurans / Q000032:analysis* / Q000302:isolation & purification; D002244:Carbon / Q000032:analysis; D060729:Coal Ash; D004147:Dioxins / Q000032:analysis* / Q000302:isolation & purification; D008401:Gas Chromatography-Mass Spectrometry / Q000379:methods*; D052638:Particulate Matter / Q000032:analysis
D001572:Benzofurans; D060729:Coal Ash; D004147:Dioxins; D052638:Particulate Matter; D002244:Carbon; C023614:dibenzofuran; C020887:dibenzo(1,4)dioxin