Evaluation, using two assessment instruments, of the American and British national guidelines for the management of sexually transmissible and genital infections.
BACKGROUND
The objective of the present study was to compare, utilising two guideline assessment instruments, six corresponding clinical practice guidelines of the British Association for Sexual Health and HIV and the Centres for Disease Control.


METHODS
Three raters independently assessed the recently published guidelines for gonorrhoea, chlamydial infection, early syphilis, pelvic inflammatory disease, bacterial vaginosis and HIV testing using two instruments, the Cluzeau and the AGREE (Appraisal of Guidelines for Research and Evaluation instrument). The Cluzeau scores were a simple percentage comparison; the AGREE scores were a standardised score for each guideline development domain. Differences were assessed using the Wilcoxson signed ranks test. Inter-rater variability was calculated on the Cluzeau instrument utilising the intragroup correlation method.


RESULTS
The British Association for Sexual Health and HIV guidelines scored higher than the Centres for Disease Control guidelines in many of the assessed domains. There were significant differences between the two in many of the scores (P = 0.026-0.028). Inter-rater concordance was high to very high at 0.70-0.83.


CONCLUSIONS
There were often major differences in scores between the two guideline groups. It is necessary for wider discussion within the profession to consider the significance of these findings.
Baird
Aisling
A
Royal Hallamshire Hospital, Glossop Road, Sheffield S10 2JF, UK.
Olarinde
Olufunso
O
Talbot
Martin
M
D019985:Benchmarking / Q000592:standards*; D019317:Evidence-Based Medicine; D006801:Humans; D017410:Practice Guidelines as Topic / Q000592:standards*; D011320:Primary Health Care / Q000592:standards*; D011785:Quality Assurance, Health Care / Q000592:standards; D011786:Quality Control; D015203:Reproducibility of Results; D012749:Sexually Transmitted Diseases / Q000175:diagnosis* / Q000517:prevention & control*; D006113:United Kingdom; D014481:United States