title: Neonatal necrotising fasciitis--Varanasi experience.
abstract: Neonatal necrotising fasciitis (NNF) is a rare and fatal disorder. Successful outcome depends on timely intervention. This paper presents single-centre experience of presentation, management and outcome of the condition. Fifteen patients of NNF were managed during the study period of 5 years. Parameters studied were age, sex, site of involvement and treatment. Treatment included intravenous (i.v.) antibiotics and conservative surgery. Age of presentation was 10-28 days. Male to female ratio was 2:1. Neck and scalp were the commonest site (53.3%). Culture reports were unimicrobial in 66% with predominance of Staphylococcus species. Predisposing factors included rural environment (100%), malnourishment (60%), boils (40%) and scratch injury (13%). Forty per cent had idiopathic NNF. Wound healing was by secondary intention in 46.6% and skin grafting in 53.3%. Overall survival was 80%, while the premature had poorer outcome. NNF is a serious disorder. Early treatment with i.v. antibiotics and supportive measures followed by debridement improves survival.
authors: Department of Pediatric Surgery, Institute of Medical Sciences, Banaras Hindu University, Varanasi 221005, Uttar Pradesh, India.
authors: Ajay Narayan
authors: AN
authors: Gangopadhyay
authors: Anand
authors: A
authors: Pandey
authors: Vijay Dutt
authors: VD
authors: Upadhyay
authors: Shiv Prasad
authors: SP
authors: Sharma
authors: Dinesh Kumar
authors: DK
authors: Gupta
authors: Vijayendra
authors: V
authors: Kumar
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001458:Bandages; D015331:Cohort Studies; D003646:Debridement; D019115:Fasciitis, Necrotizing / Q000209:etiology / Q000401:mortality / Q000628:therapy*; D005260:Female; D006801:Humans; D007194:India; D007231:Infant, Newborn; D007234:Infant, Premature; D007235:Infant, Premature, Diseases / Q000209:etiology / Q000401:mortality / Q000628:therapy*; D008297:Male; D012189:Retrospective Studies; D012307:Risk Factors; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents