Transient asymptomatic bradycardia in patients on infusional 5-fluorouracil.
The incidence of 5-fluorouracil (5-FU)-related cardiotoxicity seems to be dosage and schedule dependent. Although various other cardiac events have been reported in literature, a series of patients having transient asymptomatic bradycardia has not been reported in the literature as yet. We report such a series of patients who had transient asymptomatic bradycardia after being treated with continuous infusion 5-FU. We plan to do a Holter study during the period of bradycardia in subsequent patients and this may throw more light on the issue.
Talapatra
K
K
Department of Radiation Oncology, Unit 2, Christian Medical College, Vellore - 430 002, India.
Rajesh
I
I
Rajesh
B
B
Selvamani
B
B
Subhashini
J
J
D000328:Adult; D000964:Antimetabolites, Antineoplastic / Q000009:adverse effects*; D001919:Bradycardia / Q000139:chemically induced* / Q000175:diagnosis*; D005260:Female; D005472:Fluorouracil / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000188:drug therapy*
D000964:Antimetabolites, Antineoplastic; D005472:Fluorouracil