A single-molecule assay to directly identify solvent-accessible disulfide bonds and probe their effect on protein folding.
Ainavarapu
Sri Rama Koti
SR
Department of Biological Sciences, Columbia University, New York, New York 10027, USA. sra2104@columbia.edu
Wiita
Arun P
AP
Huang
Hector H
HH
Fernandez
Julio M
JM
D000818:Animals; D064211:Connectin; D003545:Cysteine / Q000032:analysis*; D004220:Disulfides / Q000032:analysis*; D006801:Humans; D009124:Muscle Proteins / Q000737:chemistry / Q000235:genetics; D020815:Polyproteins / Q000737:chemistry; D017510:Protein Folding; D011494:Protein Kinases / Q000737:chemistry / Q000235:genetics; D017434:Protein Structure, Tertiary; D011506:Proteins / Q000737:chemistry*; D012997:Solvents / Q000737:chemistry
D064211:Connectin; D004220:Disulfides; D009124:Muscle Proteins; D020815:Polyproteins; D011506:Proteins; D012997:Solvents; C577285:TTN protein, human; D011494:Protein Kinases; D003545:Cysteine