Combined hepatocellular carcinoma and cholangiocarcinoma: a case report and review of the literature.
BACKGROUND
Combined hepatocellular carcinoma and cholangiocarcinoma (cHCC-CC) is a rare histopathologic form of primary liver cancer. We report a case of cHCC-CC and review the literature.


METHODS
The clinicopathological features of a 61-year-old male were retrospectively analyzed.


RESULTS
Hepatocellular carcinoma (HCC) was preoperatively considered on the basis of clinical findings resembling those associated with HCC. Hepatectomy was therefore performed. Microscopically, the specimen displayed histological features of cHCC-CC. The patient has remained alive after follow-up for 3 months without evidence of recurrence and metastasis.


CONCLUSIONS
It is difficult to make a correct preoperative diagnosis of cHCC-CC and hepatic resection is the treatment of choice.
Zhou
Yan-Ming
YM
Department of Special Treatment, Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai 200438, China. zhouyms@yahoo.com.cn
Yang
Jia-Mei
JM
Wang
Bin
B
Xu
Feng
F
Tong
Ying
Y
Li
Dian-Qi
DQ
D001650:Bile Duct Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000628:therapy; D001653:Bile Ducts, Intrahepatic; D006528:Carcinoma, Hepatocellular / Q000000981:diagnostic imaging / Q000473:pathology* / Q000628:therapy; D018281:Cholangiocarcinoma / Q000000981:diagnostic imaging / Q000473:pathology* / Q000628:therapy; D006801:Humans; D008113:Liver Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000628:therapy; D008297:Male; D008875:Middle Aged; D014057:Tomography, X-Ray Computed