title: Characterization of focal right atrial appendage tachycardia.
abstract: OBJECTIVE
  Though right atrial appendage tachycardia (RAAT) has been described, no studies to date have focused on its clinical characterization. The aim of the present study was to analyze its clinical, electrocardiographic (ECG), and electrophysiologic (EP) characteristics and the results of radiofrequency ablation (RFA) in RAAT.
  
  
  RESULTS
  Out of 186 consecutive patients undergoing RFA for AT, 15 (8%) had focal RAAT. Mapping was performed using conventional catheters or a 3D electroanatomic mapping system. Patients with RAAT were more likely to be male (66 vs. 38%; P= 0.013) and younger (32 +/- 12.6 vs. 55 +/- 13.2 years; P < 0.001) than patients with AT originating elsewhere. They were also more likely to have dyspnea (27 vs. 7.6%; P = 0.03), incessant tachycardia (53 vs. 16%; P < 0.001), and left ventricular systolic dysfunction (27 vs. 5%; P = 0.018). RFA was effective in all patients (100 vs. 75%; P = 0.022) and no recurrences (0 vs. 8%; P = 0.31) were observed during a mean follow-up of 37 +/- 36 months. A specific ECG pattern was identified, consisting of negative P-waves in leads V1-V2 and a transition to positivity in the rest of the precordial leads. This ECG pattern correctly identified RAAT with a sensitivity of 100%, a specificity of 98%, a positive predictive value of 88%, and a negative predictive value of 100%.
  
  
  CONCLUSIONS
  Right atrial appendage tachycardia is more prevalent in young male patients and is commonly associated with tachycardiomyopathy. RFA is effective over long-term follow-up. A characteristic ECG pattern identifies RAAT with a very high sensitivity and specificity.
authors: Arrhythmia Section, Cardiology Department, Thorax Institute, Hospital Clinic, University of Barcelona, Villarroel 170, Barcelona 08036, Catalonia, Spain.
authors: Xavier
authors: X
authors: Freixa
authors: Antonio
authors: A
authors: Berruezo
authors: Lluís
authors: L
authors: Mont
authors: Santiago
authors: S
authors: Magnani
authors: Begoña
authors: B
authors: Benito
authors: Jose María
authors: JM
authors: Tolosana
authors: Pablo
authors: P
authors: Perafan
authors: David
authors: D
authors: Tamborero
authors: Josep
authors: J
authors: Brugada
mesh_terms: D000328:Adult; D000368:Aged; D020517:Atrial Appendage / Q000503:physiopathology* / Q000601:surgery; D017115:Catheter Ablation; D004417:Dyspnea / Q000209:etiology / Q000503:physiopathology; D004562:Electrocardiography; D022062:Electrophysiologic Techniques, Cardiac; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D012680:Sensitivity and Specificity; D013612:Tachycardia, Ectopic Atrial / Q000150:complications / Q000503:physiopathology* / Q000601:surgery; D016896:Treatment Outcome; D018487:Ventricular Dysfunction, Left / Q000209:etiology / Q000503:physiopathology