title: Persistence of Legionella in hospital water supplies and nosocomial Legionnaires' disease.
abstract: The molecular epidemiology of clinical and environmental Legionella species isolates was studied in seven hospitals from 1989 to 2006. The number of environmental pulsed field gel electrophoresis (PFGE) patterns ranged from one to nine according to the hospital. Genomic PFGE pattern persistence was observed in 71% of the hospitals, even after 17 years in some hospitals, and the relationship between environmental and clinical isolates was established. The isolates associated with hospital-acquired Legionnaires' disease corresponded to the persistent environmental PFGE patterns of Legionella pneumophila in potable water supplies.
authors: Infectious Diseases Unit, Fundació Institut d'Investigació Germans Trias i Pujol, Autonomous University of Barcelona, Hospital Universitario Germans Trias i Pujol, Badalona, Barcelona, Spain.
authors: Marian
authors: M
authors: Garcia-Nuñez
authors: Nieves
authors: N
authors: Sopena
authors: Sonia
authors: S
authors: Ragull
authors: Maria Luisa
authors: ML
authors: Pedro-Botet
authors: Josep
authors: J
authors: Morera
authors: Miguel
authors: M
authors: Sabria
mesh_terms: D016000:Cluster Analysis; D003428:Cross Infection / Q000453:epidemiology*; D016172:DNA Fingerprinting; D004269:DNA, Bacterial / Q000235:genetics; D016521:Electrophoresis, Gel, Pulsed-Field; D005838:Genotype; D006761:Hospitals; D006801:Humans; D016952:Legionella pneumophila / Q000145:classification / Q000302:isolation & purification*; D007877:Legionnaires' Disease / Q000453:epidemiology*; D017720:Molecular Epidemiology; D014871:Water Microbiology; D014881:Water Supply
chemical_list: D004269:DNA, Bacterial