Kaposi's sarcoma after liver transplantation from a donor with a history of ventriculoperitoneal shunt and craniotomy for primary central nervous system lymphoma: report of a case.
The transplantation of organs from donors who have undergone shunt surgery or craniotomy for a malignant central nervous system (CNS) tumor is controversial. We report a case of Kaposi's sarcoma (KS) developing as a result of immunosuppression in the recipient of a liver transplant from a donor who underwent craniotomy and ventriculoperitoneal shunt surgery for primary CNS lymphoma. Polymerase chain reaction assay did not isolate human herpes virus-8 in the Kaposi lesions. To our knowledge, this is the only case ever reported of KS developing after liver transplantation from a donor with lymphoma. Thus, with appropriate screening to exclude possible dissemination, patients with a history of high-grade primary CNS lymphoma treated by ventriculoperitoneal shunt and craniotomy may be accepted as donors.
Isik
Burak
B
Department of Surgery, Inonu University Medical School, Genel Cerrahi AD, Malatya 44280, Turkey.
Yilmaz
Sezai
S
Kirimlioglu
Vedat
V
Kirimlioglu
Hale
H
Yilmaz
Mehmet
M
Sogutlu
Gokhan
G
Ara
Cengiz
C
Katz
Daniel
D
D001706:Biopsy; D016543:Central Nervous System Neoplasms / Q000175:diagnosis / Q000601:surgery*; D003399:Craniotomy / Q000379:methods*; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007165:Immunosuppression Therapy / Q000009:adverse effects*; D016031:Liver Transplantation / Q000473:pathology*; D008223:Lymphoma / Q000175:diagnosis / Q000601:surgery*; D008875:Middle Aged; D012514:Sarcoma, Kaposi / Q000209:etiology* / Q000473:pathology; D014019:Tissue Donors; D017287:Ventriculoperitoneal Shunt / Q000379:methods*