[Diagnosis and therapy of osteogenesis imperfecta].
Osteogenesis imperfecta (OI) is a congenital connective tissue disorder with an incidence of up to 1:30,000. Patients suffer from deformities and fractures, and many of them never reach ambulation. The therapy consists of conservative, medicamentous and operative procedures that are described in this article.
Meurer
A
A
Orthopädische Klinik , Johannes-Gutenberg-Universität, Langenbeckstrasse 1, 55131 Mainz, Deutschland. meurer@uni-mainz.de
Lewens
T
T
Schmitt
D
D
Vetter
T
T
Drees
P
P
D000328:Adult; D050071:Bone Density Conservation Agents / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D003937:Diagnosis, Differential; D004164:Diphosphonates / Q000627:therapeutic use; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D019637:Orthopedic Procedures; D010013:Osteogenesis Imperfecta / Q000145:classification / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000601:surgery; D011859:Radiography; D013997:Time Factors
D050071:Bone Density Conservation Agents; D004164:Diphosphonates