Hypo, hype and 'hyp' human proteins.
Genes with unknown function are called orphan genes while their transcripts and peptides are called hypothetical proteins. There are many genes and their associated proteins that remain uncharacterized in the human genome. A database of human hypothetical proteins with ascribed functions could be helpful for biologists to search for potential proteins of interest. In recent years, the rapid completion of genome sequences has created essential information to link genes to gene products. In order to better explain functions for un-annotated proteins we designed BioinformaTRICKS (an open source project) and used it to develop a database called HYPO.


BACKGROUND
The database is available for free at http://pc-dugong.ruc.dk:8080.
Suravajhala
Prashanth
P
Institute for Science, Systems and Models, Roskilde University, DK 4000 Roskilde, Denmark. prash@ruc.dk