title: Immersion behavior of gelatin-containing calcium phosphate cement.
abstract: Calcium phosphate cements (CPCs) have many favorable properties that support their clinical use as bone defect repair. However, it is difficult to deliver to the required site and hard to compact adequately due to inherently low ductility of ceramics. The aim of this study focused on the effect of the gelatin content on properties of CPCs. The diametral tensile strength, morphology, and weight loss of gelatin cements were evaluated after immersion in physiological solution, in addition to setting time. The results indicated that the setting time significantly increased with increasing gelatin amount. The 2 wt.% gelatin could make CPCs attain the maximum strength value of 2.1 MPa at 15-day immersion, while 1.6 MPa for the cement without gelatin. It is concluded that the presence of gelatin improved mechanical properties of CPCs; in particular, 2 wt.% gelatin. CPCs containing 2 wt.% gelatin hardened in an acceptable time recommended for clinical applications.
authors: Institute of Stomatology, Chung-Shan Medical University, Taichung 402, Taiwan.
authors: Ming-You
authors: MY
authors: Shie
authors: David Chan-Hen
authors: DC
authors: Chen
authors: Chuan-Yeh
authors: CY
authors: Wang
authors: Ting-Yi
authors: TY
authors: Chiang
authors: Shinn-Jyh
authors: SJ
authors: Ding
mesh_terms: D000818:Animals; D001843:Bone Cements; D002130:Calcium Phosphates / Q000737:chemistry*; D002417:Cattle; D005780:Gelatin / Q000737:chemistry*; D006244:Hardness; D008855:Microscopy, Electron, Scanning; D012996:Solutions; D013499:Surface Properties; D013718:Tensile Strength; D013997:Time Factors; D014961:X-Ray Diffraction
chemical_list: D001843:Bone Cements; D002130:Calcium Phosphates; D012996:Solutions; D005780:Gelatin; C020243:calcium phosphate