title: A convergent synthesis of the tricyclic core of the dictyosphaeric acids.
abstract: The first synthetic route to the tricyclic core of the dictyosphaeric acids has been established starting from readily available (S)-(-)-4-(tert-butyldimethylsilyloxy)cyclohexenone and involving 9 steps, including a ring-closing metathesis to produce a 13-membered macrolactone, and a doubly tethered intramolecular Michael addition.
authors: Department of Chemistry, University of York, Heslington, York YO10 5DD, United Kingdom.
authors: Christopher W
authors: CW
authors: Barfoot
authors: Alan R
authors: AR
authors: Burns
authors: Michael G
authors: MG
authors: Edwards
authors: Martin N
authors: MN
authors: Kenworthy
authors: Mahmood
authors: M
authors: Ahmed
authors: Stephen E
authors: SE
authors: Shanahan
authors: Richard J K
authors: RJ
authors: Taylor
mesh_terms: D003500:Cyclization; D007783:Lactones / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D010407:Penicillium / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D007783:Lactones; C491891:dictyosphaeric acid A; C491892:dictyosphaeric acid B