Lyophilization of proteins.
This chapter describes the methods that can be applied to successfully freeze-dry proteins. Laboratory applications are given at small scale, typified by the purification of a protein intermediate as part of the analytical characterization of a protein, and at intermediate scale, as illustrated by the pilot development of a lyophilized protein reference material such as for use in bioassay or immunoassay. Advice on common problems with freeze-drying of proteins is also given.
Matejtschuk
Paul
P
Standardization Science, National Institute of Biological Standards and Control, Potters Bar, Hertfordshire, UK.
D005612:Freeze Drying / Q000379:methods / Q000592:standards; D011506:Proteins / Q000737:chemistry*
D011506:Proteins