[Hormonal contraception in men].
Over the past few decades, female hormonal contraception has been seen to be very successful. However, this has still not resulted in a hormonal contraceptive for men. Certain injectable combinations ofandrogens and progestagens have been found to suppress spermatogenesis. All combinations that have been tested so far suffer from a relative lack of efficacy, a long lag time to achieve azoospermia, requiring the user to undergo one or more semen analyses, a moderate user friendliness, and concerns about the long-term safety and reversibility. It is not to be expected that male hormonal contraception will become a serious alternative to the already existing female equivalent during the coming 5 years.
de Ronde
W
W
VU Medisch Centrum, De Boelelaan 1117, 1081 HV Amsterdam. p.deronde@vumc.nl
Meuleman
E J H
EJ
D003267:Contraception / Q000379:methods*; D003272:Contraceptive Agents, Male / Q000008:administration & dosage*; D006727:Hormone Antagonists; D006801:Humans; D008297:Male; D012449:Safety; D013076:Sperm Count; D013091:Spermatogenesis / Q000187:drug effects*; D013092:Spermatogenesis-Blocking Agents / Q000008:administration & dosage*; D016896:Treatment Outcome
D003272:Contraceptive Agents, Male; D006727:Hormone Antagonists; D013092:Spermatogenesis-Blocking Agents