title: [Lateral pelvic metastasis and micrometastasis in low rectal cancer].
abstract: OBJECTIVE
  To study lateral pelvic metastasis and micrometastasis of low rectal cancer and elucidate their prognostic value.
  
  
  METHODS
  Whole-mount slice and tissue microarray of dissected lateral pelvic specimen from 67 cases of low rectal cancer were examined, and the included cases were followed up.
  
  
  RESULTS
  Twelve specimens were diagnosed as lateral metastasis, while another 10 were proved to bear micrometastasis. Most of the involved metastatic lymph nodes (82.9%) were smaller than 5 mm in diameter. Internal iliac, obturator regions and middle rectal root were more likely to be involved by tumors. Patients with lateral metastasis suffered more recurrence and poorer survival.
  
  
  CONCLUSIONS
  Lateral pelvic metastasis could be observed in low rectal cancer and its incidence differed among lateral pelvic regions. Patients with lateral spread predisposed poor prognosis, thus underlies the value of pre/postoperative adjuvant therapy.
authors: Department of General Surgery III, West China Hospital, Sichuan University, Chengdu 610041, China.
authors: Cun
authors: C
authors: Wang
authors: Zong-guang
authors: ZG
authors: Zhou
authors: Yong-yang
authors: YY
authors: Yu
authors: Yuan
authors: Y
authors: Li
authors: Lie
authors: L
authors: Yang
authors: Zhong
authors: Z
authors: Cheng
authors: Wen-zhang
authors: WZ
authors: Lei
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D053208:Kaplan-Meier Estimate; D008197:Lymph Node Excision; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D010388:Pelvis / Q000473:pathology*; D011379:Prognosis; D012004:Rectal Neoplasms / Q000473:pathology* / Q000601:surgery