[Effect of aging on preoperative oxidative stress].
We investigated the effect of aging on preoperative oxidative stress by measuring serum hydroperoxide values in 35 patients who underwent elective surgery under general anesthesia. A small amount of blood was withdrawn through an intravenous catheter and serum hydroperoxide values were measured using the Free Radical Analytic System (FRAS4). Aging and oxidative stress are significantly and positively correlated (P < 0.001, r = 0.622). Although the reason is unknown, oxidative stress increases concomitantly with aging.
Satoh
Tomohiro
T
Department of Anesthesiology, Sapporo Medical University School of Medicine, Sapporo 060-8543.
Yamakage
Michiaki
M
Satoh
Jun-ichi
J
Namiki
Akiyoshi
A
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000502:physiology*; D000768:Anesthesia, General; D015415:Biomarkers / Q000097:blood; D003124:Colorimetry; D017558:Elective Surgical Procedures; D005260:Female; D006801:Humans; D006861:Hydrogen Peroxide / Q000097:blood*; D008297:Male; D008875:Middle Aged; D018384:Oxidative Stress / Q000502:physiology*; D017382:Reactive Oxygen Species / Q000097:blood
D015415:Biomarkers; D017382:Reactive Oxygen Species; D006861:Hydrogen Peroxide