title: Effect of alcohols on the stability of iprodione in solution.
abstract: Both primary and secondary alcohols degrade iprodione, 3-(3,5-dichlorophenyl)-N-(1-methylethyl)-2,4-dioxo-1-imidazolidine carboxamide. Steric hindrance has been found to have an inverse effect on the rate of its decomposition, and a fully substituted alcohol, such as tert-butanol, does not degrade iprodione due to extreme steric hindrance. The instability of iprodione in alcohol was found to be a function of the structure of the alcohol. The product, N-(3,5-dichlorophenyl)-3-(1-methylethyl)-2,4-dioxo-1-imidazolidine carboxamide, is obtained from all of the reacting alcohols. Confirmation of this structure came from the consideration of its NMR, mass spectral, and elemental analysis data.
authors: Pesticide Section, Consumer Analytical Laboratory, Ohio Department of Agriculture, 8995 East Main Street, Reynoldsburg, OH 43068, USA. Anisuzzaman@agri.ohio.gov
authors: Abul K M
authors: AK
authors: Anisuzzaman
authors: Thomas
authors: T
authors: Storehalder
authors: David C
authors: DC
authors: Williams
authors: Norlida
authors: N
authors: Ogg
authors: Tracee D
authors: TD
authors: Kilbourne
authors: Jayaseharan
authors: J
authors: Johnsamuel
authors: Charles E
authors: CE
authors: Cottrell
mesh_terms: D000438:Alcohols / Q000494:pharmacology*; D000620:Aminoimidazole Carboxamide / Q000031:analogs & derivatives* / Q000737:chemistry; D004355:Drug Stability; D005659:Fungicides, Industrial / Q000737:chemistry*; D008401:Gas Chromatography-Mass Spectrometry; D006827:Hydantoins / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D000432:Methanol / Q000737:chemistry; D008958:Models, Molecular; D012996:Solutions; D020002:tert-Butyl Alcohol / Q000494:pharmacology
chemical_list: D000438:Alcohols; D005659:Fungicides, Industrial; D006827:Hydantoins; D012996:Solutions; D000620:Aminoimidazole Carboxamide; D020002:tert-Butyl Alcohol; C033148:iprodione; D000432:Methanol