Novel technique for fabricating double-layered tubular constructs consisting of two vascular cell types in collagen gels used as templates for three-dimensional tissues.
Double-layered tubular constructs consisting of two vascular cell types in collagen gels were fabricated using a previously developed technique [Takei et al., Biotechnol. Bioeng., 95, 1-7 (2006)]. Histological examination suggested that shear stress (4.0 dyn/cm2) on the luminal surface of the constructs induced morphological changes in their walls.
Takei
Takayuki
T
Department of Chemical Engineering, Faculty of Engineering, Kyushu University, 744 Motooka, Nishi-ku, Fukuoka 819-0385, Japan.
Yamaguchi
Shinsuke
S
Sakai
Shinji
S
Ijima
Hiroyuki
H
Kawakami
Koei
K
D000818:Animals; D001808:Blood Vessels / Q000166:cytology; D003094:Collagen / Q000737:chemistry; D004730:Endothelium, Vascular / Q000737:chemistry / Q000166:cytology*; D005782:Gels / Q000737:chemistry; D051379:Mice; D032389:Myocytes, Smooth Muscle / Q000737:chemistry / Q000166:cytology*; D009924:Organ Culture Techniques / Q000379:methods*; D023822:Tissue Engineering / Q000379:methods*
D005782:Gels; D003094:Collagen