title: [Hyperphosphatasia and hypophosphatasia in childhood].
abstract: The treatment of phosphate diabetes and hyperphosphatasia requires an interdisciplinary therapy concept between paediatricians and orthopaedic surgeons. The surgical challenge is the correction of the multiplanar bending deformities and the pathological fractures. Different techniques are discussed in the literature without an outstanding recommendation for a special approach. This contribution gives an overview of the published methods and discusses various surgical concepts in view of our own clinical experience.
authors: Orthopädische Klinik und Poliklinik, Johannes-Gutenberg-Universität Mainz, Langenbeckstrasse 1, 55101 Mainz, Deutschland. drees@uni-mainz.de
authors: P
authors: P
authors: Drees
authors: D
authors: D
authors: Schmidt
authors: T
authors: T
authors: Lewens
authors: T
authors: T
authors: Vetter
authors: A
authors: A
authors: Meurer
mesh_terms: D000293:Adolescent; D000469:Alkaline Phosphatase / Q000097:blood; D050071:Bone Density Conservation Agents / Q000008:administration & dosage / Q000627:therapeutic use; D002117:Calcitriol / Q000008:administration & dosage / Q000627:therapeutic use; D002118:Calcium / Q000097:blood; D002648:Child; D002675:Child, Preschool; D004359:Drug Therapy, Combination; D016267:External Fixators; D053098:Familial Hypophosphatemic Rickets / Q000097:blood / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000601:surgery; D005260:Female; D005269:Femur / Q000601:surgery; D005500:Follow-Up Studies; D006801:Humans; D007014:Hypophosphatasia / Q000097:blood / Q000175:diagnosis / Q000235:genetics; D007223:Infant; D008297:Male; D019637:Orthopedic Procedures; D010001:Osteitis Deformans / Q000097:blood / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000601:surgery; D010027:Osteotomy / Q000379:methods; D010710:Phosphates / Q000008:administration & dosage / Q000097:blood / Q000627:therapeutic use; D011859:Radiography; D013977:Tibia / Q000601:surgery; D013997:Time Factors
chemical_list: D050071:Bone Density Conservation Agents; D010710:Phosphates; D000469:Alkaline Phosphatase; D002117:Calcitriol; D002118:Calcium