[A case of angiosarcoma of pelvis with pulmonary metastases which responded to paclitaxel].
A 60-year-old man was admitted to our hospital complaining of back pain and bloody sputum. Chest CT scan showed characteristic multiple small nodules with central dense opacity and surrounding faint opacity, suggesting lesions with hemorrhage. Bone scintigram and MRI revealed multiple osteolytic lesions in pelvis and lumbar spine. Biopsy of the bone lesion established a diagnosis of angiosarcoma. Chemotherapy with paclitaxel and palliative radiotherapy for the bone were initiated. Pulmonary metastases dramatically diminished after 4 courses of paclitaxel treatment. After eight weeks, the tumor recurred. Salvage chemotherapy of weekly administration of docetaxel yielded limited effects. The patient died of cancer one year after treatment initiation.
Tada
Yuji
Y
Dept. of Respirology, Graduate School of Medicine, Chiba University.
Takiguchi
Yuichi
Y
Terada
Jiro
J
Yoshida
Takako
T
Shinozaki
Aya
A
Sakao
Seiichiro
S
Kasahara
Yasunori
Y
Kurosu
Katsushi
K
Tanabe
Nobuhiro
N
Tatsumi
Koichiro
K
Hiroshima
Kenzo
K
Kuriyama
Takayuki
T
D000972:Antineoplastic Agents, Phytogenic / Q000627:therapeutic use*; D001859:Bone Neoplasms / Q000188:drug therapy* / Q000473:pathology; D006394:Hemangiosarcoma / Q000188:drug therapy* / Q000473:pathology; D006801:Humans; D008175:Lung Neoplasms / Q000556:secondary*; D008297:Male; D008875:Middle Aged; D017239:Paclitaxel / Q000627:therapeutic use*; D010384:Pelvic Bones; D016879:Salvage Therapy
D000972:Antineoplastic Agents, Phytogenic; D017239:Paclitaxel