title: Repair of an infrarenal abdominal aortic aneurysm is associated with persistent left ventricular diastolic dysfunction.
abstract: BACKGROUND
  Left ventricular (LV) diastolic function has received much attention recently. However, few studies have evaluated LV diastolic function in the perioperative period. The aim of this study was to elucidate perioperative changes in diastolic function using tissue Doppler imaging (TDI) in patients undergoing repair of an infrarenal abdominal aortic aneurysm (AAA).
  
  
  METHODS
  Eight patients undergoing repair of an infrarenal AAA were studied prospectively using transesophageal echocardiography. Doppler echocardiographic examinations were performed before the surgical procedure (T1), immediately before aortic unclamping (T2), 30 minutes after aortic unclamping (T3), and at the end of surgery (T4).
  
  
  RESULTS
  Pulmonary edema developed in two patients on postoperative day 1. These two patients had the lowest early diastolic mitral annular velocity (Ea) of the study group at the end of surgery. The ratio of the peak velocity of early mitral inflow (E) to the peak velocity of atrial inflow was significantly decreased at T3 and T4. The systolic ejection velocity was significantly decreased at T3, but returned to the baseline value at T4. The Ea was significantly decreased at T3 and T4. The E/Ea ratio showed a progressive rise and was significantly increased at T3 and T4.
  
  
  CONCLUSIONS
  In patients undergoing repair of an infrarenal AAA, the Ea derived using TDI decreases at T3 and is still reduced at T4. The E/Ea ratio, which is used to estimate LV filling pressures, is significantly increased at T3 and T4. Further research is required to confirm the development of diastolic dysfunction and determine its possible association with increased postoperative morbidity and mortality.
authors: Department of Anesthesia and Pain Control, Graduate School of Medicine, Nippon Medical School, Japan.
authors: Hiroyasu
authors: H
authors: Bitoh
authors: Kazuhiro
authors: K
authors: Nakanishi
authors: Shinhiro
authors: S
authors: Takeda
authors: Chol
authors: C
authors: Kim
authors: Masaki
authors: M
authors: Mori
authors: Atsuhiro
authors: A
authors: Sakamoto
mesh_terms: D017544:Aortic Aneurysm, Abdominal / Q000601:surgery*; D003971:Diastole; D015150:Echocardiography, Doppler; D017548:Echocardiography, Transesophageal; D005260:Female; D006801:Humans; D007668:Kidney; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D011446:Prospective Studies; D018487:Ventricular Dysfunction, Left / Q000209:etiology*