Stereoselective RhI-catalyzed tandem conjugate addition of boronic acids-Michael cyclization.
The first examples of the stereoselective sequence RhI-catalyzed tandem conjugate addition of boronic acids to enones-Michael cyclization, is reported. The reaction is carried out in dioxane-H2O at rt, and 1,2,3-trisubstituted indans are obtained in a highly regio- and stereoselective fashion.
Navarro
Cristina
C
Departamento de Química Orgánica, Facultad de Química, Universidad Complutense, 28040-Madrid, Spain.
Csákÿ
Aurelio G
AG