Acute acalculous cholecystitis during the course of primary Epstein-Barr virus infection: a new case and a review of the literature.
OBJECTIVE
The aim of this study was to describe a case of acute acalculous cholecystitis occurring in the course of primary Epstein-Barr virus (EBV) infection.


METHODS
The clinical features of the case were analyzed and compared to those of three other similar cases reported in the international literature.


RESULTS
All cases occurred in European females with cholestatic hepatitis, presented with gallbladder wall thickening, and recovered uneventfully without the need for surgical intervention.


CONCLUSIONS
Acute acalculous cholecystitis may occur during the course of acute EBV infection, especially in patients with cholestatic hepatitis. Clinicians should be aware of the possible involvement of the gallbladder during EBV infection to avoid unnecessary invasive procedures or the overuse of antibiotics.
Iaria
Chiara
C
AILMI (Associazione Italiana per la Lotta contro le Malattie Infettive; Italian Association for the Control of Infectious Diseases), University of Messina, Messina, Italy.
Arena
Lucia
L
Di Maio
Giovanni
G
Fracassi
Maria Grazia
MG
Leonardi
Maria Silvana
MS
Famulari
Ciro
C
Cascio
Antonio
A
D042101:Acalculous Cholecystitis / Q000150:complications* / Q000821:virology; D000293:Adolescent; D000328:Adult; D020031:Epstein-Barr Virus Infections / Q000150:complications*; D005260:Female; D006801:Humans; D008875:Middle Aged