title: The use of porcine dermal collagen implants in assisting abdominal wall closure of pediatric renal transplant recipients with donor size discrepancy.
abstract: Children may have kidneys transplanted from donors larger than themselves. Abdominal wall closure may be difficult, with risks of abdominal compartment syndrome and graft compromise. Meshes used to facilitate closure may cause dense intra-abdominal adhesions, making further surgery or peritoneal dialysis difficult. We present five cases in which abdominal wall closure was facilitated by porcine dermal collagen implant. Five children (2-15 yr) received transplanted kidneys from adult donors of significantly greater weight. In four recipients, the kidney was transplanted onto the aorta and vena cava intra-abdominally using a midline incision. In the fifth, the kidney was anastomosed onto the iliac vessels. The skin overlying the implant was closed normally. Maximum follow-up was three yr. In all cases, primary closure was achieved. One child received a second intra-abdominal transplant as an emergency, which later failed. The other kidneys are functioning well. One recipient developed a small incisional hernia three yr post-transplant. Another developed a skin dehiscence over the implant 23 days post-operatively. The implant was removed and skin closed. The other two recipients recovered well. Porcine dermal collagen implant is a helpful adjunct to abdominal wall closure following organ transplantation in children with donor size discrepancy.
authors: Department of Surgery, Southmead Hospital, North Bristol NHS Trust, Bristol, UK.
authors: Alanna
authors: A
authors: Pentlow
authors: Neil J
authors: NJ
authors: Smart
authors: Sarah K
authors: SK
authors: Richards
authors: Carol D
authors: CD
authors: Inward
authors: Justin D T
authors: JD
authors: Morgan
mesh_terms: D034861:Abdominal Wall / Q000601:surgery*; D000293:Adolescent; D001672:Biocompatible Materials / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D003094:Collagen / Q000627:therapeutic use*; D017809:Fatal Outcome; D006801:Humans; D016030:Kidney Transplantation; D008297:Male
chemical_list: D001672:Biocompatible Materials; C422414:Permacol; D003094:Collagen