New method for long-term monitoring of intragastric pH.
OBJECTIVE
Consecutive monitoring of intragastric pH using the Bravo capsule.


METHODS
We put threads through a Bravo capsule and then affixed it to the gastric wall by endoscopic hemoclipping in seven subjects. Study data were uploaded to a computer via Datalink every 48 h. In this way, repeated monitoring of intragastric pH was undertaken.


RESULTS
All subjects were able to monitor gastric pH over a 1-wk period, and five for > 2 wk. No complications were encountered during the monitoring. After pH monitoring, we safely retrieved the capsule endoscopically.


CONCLUSIONS
Clipping a Bravo capsule onto the gastric wall enabled long-term intragastric pH monitoring. This is a methodological report of pH monitoring over a period of > 2 wk.
Ono
Shouko
S
Division of Endoscopy, Hokkaido University Hospital Nishi-5, Kita-14, Kita-ku, Sapporo 060-8648, Japan.
Kato
Mototsugu
M
Ono
Yuji
Y
Asaka
Masahiro
M
D000284:Administration, Oral; D000897:Anti-Ulcer Agents / Q000008:administration & dosage; D011211:Electric Power Supplies; D004867:Equipment Design; D005744:Gastric Acid / Q000378:metabolism*; D005745:Gastric Acidity Determination / Q000295:instrumentation*; D005753:Gastric Mucosa / Q000378:metabolism*; D005773:Gastroscopy; D006801:Humans; D006863:Hydrogen-Ion Concentration; D018670:Monitoring, Ambulatory / Q000295:instrumentation*; D011899:Ranitidine / Q000008:administration & dosage; D012815:Signal Processing, Computer-Assisted; D013270:Stomach / Q000187:drug effects / Q000601:surgery; D013686:Telemetry / Q000295:instrumentation*; D013997:Time Factors
D000897:Anti-Ulcer Agents; D011899:Ranitidine