A fast synthetic route to GDP-sugars modified at the nucleobase.
The direct structural modification of GDP-mannose via the bromination and Suzuki-Miyaura cross-coupling of the unprotected sugar-nucleotide, to produce 8-substituted fluorescent analogues of GDP-mannose.
Collier
Alice
A
Centre for Carbohydrate Chemistry, School of Chemical Sciences and Pharmacy, University of East Anglia, Norwich, NR4 7TJ, UK.
Wagner
Gerd K
GK
D006151:Guanosine / Q000737:chemistry*; D006156:Guanosine Diphosphate Sugars / Q000138:chemical synthesis* / Q000737:chemistry*; D006157:Guanosine Monophosphate / Q000737:chemistry; D008358:Mannose / Q000737:chemistry; D015394:Molecular Structure; D013050:Spectrometry, Fluorescence; D013997:Time Factors
D006156:Guanosine Diphosphate Sugars; D006151:Guanosine; D006157:Guanosine Monophosphate; D008358:Mannose