title: Preadolescent health risk behavior as a function of prenatal cocaine exposure and gender.
abstract: OBJECTIVE
  To examine the effect of prenatal cocaine exposure on health risk behaviors during preadolescence.
  
  
  METHODS
  The present study examined prenatal cocaine exposure, gender, and environmental risk as predictors of self-reported substance use, aggression, and a disregard for safety precautions on the Youth Risk Behavior Survey in a sample of 10.5 year olds (n = 154, including 60 who were prenatally exposed to cocaine).
  
  
  RESULTS
  Gender tended to moderate the effects of prenatal cocaine exposure because exposure effects were found for boys but not girls. Boys who were prenatally exposed to cocaine reported engaging in more high-risk behavior. In examining individual outcomes, cocaine exposed boys had the highest scores for aggression, substance use, and a disregard for safety precautions, although these differences were significant only for the composite health risk behavior measure.
  
  
  CONCLUSIONS
  The findings extend earlier work showing that prenatal cocaine exposure places boys at risk for problems of inhibitory control, emotional regulation, and antisocial behavior. Research is needed to examine whether the effects of prenatal cocaine on health risk behaviors persist into adolescence, when such behaviors tend to increase.
authors: Department of Psychiatry, Drexel University College of Medicine, Philadelphia, PA, USA. David.Bennett@Drexelmed.edu
authors: David
authors: D
authors: Bennett
authors: Margaret
authors: M
authors: Bendersky
authors: Michael
authors: M
authors: Lewis
mesh_terms: D000374:Aggression / Q000523:psychology; D000704:Analysis of Variance; D002648:Child; D003042:Cocaine / Q000633:toxicity*; D003430:Cross-Sectional Studies; D005260:Female; D015438:Health Behavior; D006305:Health Status Indicators; D006801:Humans; D013287:Illicit Drugs / Q000633:toxicity*; D008137:Longitudinal Studies; D008297:Male; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects; D012307:Risk Factors; D012309:Risk-Taking; D012449:Safety; D012737:Sex Factors; D012931:Social Environment; D019966:Substance-Related Disorders / Q000453:epidemiology / Q000523:psychology
chemical_list: D013287:Illicit Drugs; D003042:Cocaine