New hope for diabetics: adult blood stem cells can make insulin.
Human blood stem cell-derived insulin-producing cells can be easily isolated from autologous blood based on their unique phenotype. They act as pancreatic islet beta-cell progenitors, as demonstrated by authentic insulin production and homing to diabetic pancreatic islets. Clinical application of these autologous blood-derived insulin-producing cells holds great promise for diabetic treatment.
Zhao
Yong
Y
Department of Medicine, University of Illinois School of Medicine, Chicago, IL 60612, USA.
D000818:Animals; D002454:Cell Differentiation / Q000502:physiology; D003920:Diabetes Mellitus / Q000628:therapy*; D006801:Humans; D007328:Insulin; D033581:Stem Cell Transplantation; D013234:Stem Cells / Q000166:cytology / Q000378:metabolism*
D007328:Insulin