A critical review of anti-adrenergic therapy in patients with heart failure and diabetes mellitus.
Anti-adrenergic therapy has been widely accepted as an important therapeutic intervention in patients with chronic heart failure. However, there has been continuing controversy regarding the risks and clinical significance of metabolic effects of different anti-adrenergic drugs. This review summarizes what has been learned from clinical trial evidence regarding the benefits of anti-adrenergic drugs in diabetic patients with chronic heart failure.
Tang
W H Wilson
WH
Department of Cardiovascular Medicine, Cleveland Clinic, OH 44195, USA. tangw@ccf.org
D018674:Adrenergic Antagonists / Q000627:therapeutic use*; D048909:Diabetes Complications / Q000188:drug therapy* / Q000378:metabolism; D003920:Diabetes Mellitus / Q000188:drug therapy* / Q000378:metabolism; D005947:Glucose / Q000378:metabolism; D006333:Heart Failure / Q000150:complications* / Q000188:drug therapy* / Q000378:metabolism; D006801:Humans
D018674:Adrenergic Antagonists; D005947:Glucose