2'-o-dimethylaminoethoxyuridine and 5-dimethylaminopropargyl deoxyuridine for at base pair recognition in triple helices.
The nucleoside analogues 2'-O-dimethylaminoethoxy uridine and 5-dimethylaminopropargyl deoxyuridine have been synthesised and incorporated into oligonucleotides. Their triplex-stabilising properties have been determined in fluorescence melting experiments.
Brennan
Lavinia
L
School of Chemistry, University of Southampton, Highfield, Southampton, United Kingdom. L.Brennan@soton.ac.uk
Peng
Guomei
G
Srinivasan
Natarajan
N
Fox
Keith R
KR
Brown
Tom
T
D020029:Base Pairing; D004247:DNA / Q000737:chemistry*; D003857:Deoxyuridine / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000737:chemistry; D008744:Methylamines / Q000138:chemical synthesis / Q000737:chemistry*; D009838:Oligodeoxyribonucleotides / Q000737:chemistry*; D014529:Uridine / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000737:chemistry
C527040:2'-o-dimethylaminoethoxyuridine; C527039:5-dimethylaminopropargyl deoxyuridine; D008744:Methylamines; D009838:Oligodeoxyribonucleotides; C051802:triplex DNA; D004247:DNA; D003857:Deoxyuridine; D014529:Uridine