title: [Evaluation of midazolam intravenous sedated patient's comfort degree in mandibular third molar surgery].
abstract: OBJECTIVE
  To evaluate the clinical efficacy and safety of continuous low-flow intravenous infusion of midazolam sedation in mandibular third molar surgery.
  
  
  METHODS
  Fifty healthy patients with symmetrically placed impacted bilateral mandibular third molars were included in this self controlled, randomized clinical study. Degree of comfort (their actual current anxiety level) was assessed using a visual analogue scale (VAS) of pain and anxiety. Patients' satisfaction and degree of amnesia were also evaluated. Vital signs and oxygen saturation were recorded.
  
  
  RESULTS
  Low dose midazolam sedation obviously increased the degree of patients' comfort and satisfaction. Vital signs and oxygen saturation levels did not differ significantly between the two groups.
  
  
  CONCLUSIONS
  Midazolam as an intravenous sedation agent in mandibular third molar surgery showed satisfactory effect on patients with mild dental fear.
authors: Department of Stomatology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China. wankuo@yahoo.com.cn
authors: Kuo
authors: K
authors: Wan
authors: Quan
authors: Q
authors: Jing
authors: Dong-Yang
authors: DY
authors: Liu
authors: Ji-Zhi
authors: JZ
authors: Zhao
authors: Xi
authors: X
authors: Chen
authors: Ya-Li
authors: YL
authors: Dong
mesh_terms: D000293:Adolescent; D000328:Adult; D000766:Anesthesia, Dental; D018686:Anesthetics, Intravenous / Q000008:administration & dosage; D016292:Procedural Sedation; D005260:Female; D006801:Humans; D008297:Male; D008874:Midazolam / Q000008:administration & dosage; D008964:Molar, Third / Q000601:surgery; D014081:Tooth Extraction; D014095:Tooth, Impacted / Q000601:surgery; D055815:Young Adult
chemical_list: D018686:Anesthetics, Intravenous; D008874:Midazolam