title: [Evaluation of macular perimetry in patients with age-related macular degeneration using the scanning laser ophthalmoscope].
abstract: OBJECTIVE
  To evaluate the correlation between anatomical changes (hard druses, soft druses, hyperpigmentation, new vessels, detachment of retinal pigment epithelium, hypopigmentation and chorioretinal atrophy) and light sensitivity in patients with age-related macular degeneration (ARMD); analyze macular sensitivity in areas with no anatomical lesions in patients with ARMD and compared them to the control group in order to detect if there was any functional lesion in areas with no anatomical changes.
  
  
  METHODS
  A cross-sectional, comparative, descriptive and analytic study was performed. The case group consisted of 31 subjects with ARMD aged between 51 and 88 years. The control group consisted of 31 "healthy" subjects, without ARMD aged between 61 and 80 years. The groups were matched for gender and age. We performed static macular perimetry, red-red, using a scanning laser ophthalmoscope (SLO). Results of macular perimetry were correlated with the anatomic lesion identified in the same site by infrared laser and color photographs.
  
  
  RESULTS
  Areas with new vessels or atrophy showed a significantly different sensitivity in relation to areas without anatomical lesions in patients with ARMD. There was significant functional loss in areas with no anatomical lesions in patients with ARMD in relation to the control group.
  
  
  CONCLUSIONS
  Areas with new vessels or atrophy could be distinct factors for worsening of the localized macular sensitivity. There might be functional loss even in areas with no apparent anatomical changes in ARMD patients.
authors.affiliation: Departamento de Oftalmologia, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil. luciomaraes@ipvisao.com.br
authors.forename: Lúcio
authors.initials: L
authors.lastname: Moraes
authors.forename: Ann E
authors.initials: AE
authors.lastname: Elsner
authors.forename: Christian
authors.initials: C
authors.lastname: Kunze
authors.forename: Hisashi
authors.initials: H
authors.lastname: Suzuki
authors.forename: Márcio Bittar
authors.initials: MB
authors.lastname: Nehemy
authors.forename: Danilo Sone
authors.initials: DS
authors.lastname: Soriano
authors.forename: Newton
authors.initials: N
authors.lastname: Kara-José
mesh_terms: D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D001284:Atrophy / Q000209:etiology / Q000473:pathology / Q000503:physiopathology; D016022:Case-Control Studies; D015350:Contrast Sensitivity / Q000502:physiology*; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D007834:Lasers; D008268:Macular Degeneration / Q000150:complications / Q000473:pathology* / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D009389:Neovascularization, Pathologic / Q000209:etiology / Q000473:pathology / Q000503:physiopathology; D019721:Ophthalmoscopes; D010857:Pigment Epithelium of Eye / Q000473:pathology / Q000503:physiopathology; D015593:Retinal Drusen / Q000209:etiology / Q000473:pathology / Q000503:physiopathology; D058609:Visual Field Tests / Q000295:instrumentation
vernacular_title: Avaliação da perimetria macular em pacientes com degeneração macular relacionada à idade por meio do oftalmoscópio de rastreamento a laser.