title: Pregnancy after in vitro fertilization-intracytoplasmic sperm injection obtained with a modified natural cycle in a BRCA1 mutation carrier.
abstract: OBJECTIVE
  To report a successful pregnancy after a semi-natural IVF cycle for a BRCA1 gene mutation carrier.
  
  
  METHODS
  Case report.
  
  
  METHODS
  University hospital.
  
  
  METHODS
  A 26-year-old patient with BRCA1 gene mutation.
  
  
  METHODS
  Semi-natural IVF cycle and intracytoplasmic sperm injection.
  
  
  METHODS
  Pregnancy rate.
  
  
  RESULTS
  A modified natural IVF cycle was performed, resulting in pregnancy and delivery.
  
  
  CONCLUSIONS
  A modified natural IVF cycle is an effective and safe solution for BRCA1 or BRCA2 mutation gene carrier women with couple infertility.
authors.affiliation: Service de Gynécologie Obstétrique, Medecine de la Reproduction, Hôpital Cochin Port-Royal, Paris, France.
authors.forename: Raphaël
authors.initials: R
authors.lastname: Hirt
authors.forename: Céline
authors.initials: C
authors.lastname: Davy
authors.forename: Juliette
authors.initials: J
authors.lastname: Guibert
authors.forename: François
authors.initials: F
authors.lastname: Olivennes
mesh_terms: D000328:Adult; D019313:BRCA1 Protein / Q000235:genetics*; D005260:Female; D005307:Fertilization in Vitro; D006579:Heterozygote; D006801:Humans; D007247:Infertility, Female / Q000235:genetics* / Q000628:therapy*; D050498:Live Birth; D009154:Mutation; D010062:Ovulation Induction / Q000379:methods*; D020554:Sperm Injections, Intracytoplasmic; D016896:Treatment Outcome
chemical_list: D019313:BRCA1 Protein