title: Self-assembly properties of some chiral N-palmitoyl amino acid surfactants in aqueous solution.
abstract: Various chiral N-palmitoyl amino acid surfactants (AAS) derived from methionine, proline, leucine, threonine, phenylalanine and phenylglycine were prepared and converted to their sodium salt. The properties of the aggregates formed in aqueous solution were studied for both the optically-active compounds and their racemic mixture. Characterization was made by surface tensiometry, fluorimetry, dynamic light scattering, circular dichroism (CD) and transmission electron microscopy. It appeared that most of the AAS studied in this work spontaneously formed different types of aggregates, including micrometer-sized aggregates. No significant difference could be found between the critical aggregation concentration (cac) value of pure enantiomers and that of the racemic forms. CD spectra did not reveal any aggregation-induced chirality.
authors.affiliation: Université Paul Sabatier, Laboratoire des Interactions Moléculaires Réactivité Chimique et Photochimique, CNRS UMR 5623, 31062 Toulouse cedex 9, France.
authors.forename: Mariana
authors.initials: M
authors.lastname: Gerova
authors.forename: Fernanda
authors.initials: F
authors.lastname: Rodrigues
authors.forename: Jean-François
authors.initials: JF
authors.lastname: Lamère
authors.forename: Alexander
authors.initials: A
authors.lastname: Dobrev
authors.forename: Suzanne
authors.initials: S
authors.lastname: Fery-Forgues
mesh_terms: D000596:Amino Acids / Q000737:chemistry*; D002942:Circular Dichroism; D046529:Microscopy, Electron, Transmission; D019906:Nuclear Magnetic Resonance, Biomolecular; D019308:Palmitic Acid / Q000737:chemistry*; D012542:Scattering, Radiation; D012996:Solutions / Q000737:chemistry; D013237:Stereoisomerism; D013501:Surface-Active Agents / Q000138:chemical synthesis*
chemical_list: D000596:Amino Acids; D012996:Solutions; D013501:Surface-Active Agents; D019308:Palmitic Acid