Chemical resolution of +/- -calanolide A, +/- -cordatolide A and their 11-demethyl analogues.
The chemical resolution of (+/-)-calanolide A and (+/-)-cordatolide A into their corresponding optically active enantiomers is described. Their inhibitory activities against HIV-1 are tested in vitro.
D019380:Anti-HIV Agents / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D020650:Combinatorial Chemistry Techniques; D015497:HIV-1 / Q000187:drug effects; D015394:Molecular Structure; D039681:Pyranocoumarins / Q000138:chemical synthesis* / Q000737:chemistry* / Q000494:pharmacology; D013237:Stereoisomerism
D019380:Anti-HIV Agents; D039681:Pyranocoumarins; C075959:calanolide A