Pregnancy outcomes after uterine artery occlusion: prospective multicentric study.
OBJECTIVE
To assess the reproductive outcomes after laparoscopic uterine artery occlusion (LUAO) and uterine artery embolization (UAE) in women with symptomatic fibroids.


METHODS
Prospective, clinical multicentric study.


METHODS
Endoscopic center in the department of obstetrics and gynecology at a hospital in the Czech Republic.


METHODS
Thirty-eight pregnant women after LUAO and 20 pregnant women after UAE.


METHODS
Laparoscopic uterine artery occlusion and UAE.


METHODS
Pregnancy, abortion, preterm delivery, and live-birth rates.


RESULTS
Pregnancies after uterine embolization had a statistically significantly higher rate for spontaneous abortion (56%) than did pregnancies after surgical uterine artery occlusion (10.5%). The risk of malpresentation (20%) and the rate for cesarean section (80%) after UAE similarly were higher than was the risk after laparoscopic occlusion; however, these differences were not statistically significant. Also, there were no significant differences between the groups in preterm deliveries (15.3% in the LUAO group vs. 20% in the UAE group).


CONCLUSIONS
Pregnancies of women who were treated with uterine embolization were at significantly increased risk for spontaneous abortion when compared with pregnancies of women treated with LUAO.
D000022:Abortion, Spontaneous / Q000209:etiology; D000328:Adult; D001158:Arteries / Q000601:surgery; D002585:Cesarean Section; D018153:Czech Republic; D005260:Female; D006801:Humans; D007746:Labor Presentation; D010535:Laparoscopy / Q000009:adverse effects*; D007889:Leiomyoma / Q000601:surgery / Q000628:therapy*; D050498:Live Birth; D011247:Pregnancy; D018873:Pregnancy Rate; D047928:Premature Birth / Q000209:etiology; D011446:Prospective Studies; D018570:Risk Assessment; D055357:Uterine Artery Embolization / Q000009:adverse effects*; D014594:Uterine Neoplasms / Q000601:surgery / Q000628:therapy*; D014599:Uterus / Q000098:blood supply*; D014656:Vascular Surgical Procedures / Q000009:adverse effects*