title: Optimization of cross-linking parameters during production of transglutaminase-hardened spherical multinuclear microcapsules by complex coacervation.
abstract: Gelatin-gum arabic spherical multinuclear microcapsules (SMMs) encapsulating peppermint oil were prepared by complex coacervation. Transglutaminase (TG) was used to harden the SMMs by complex coacervation instead of traditional reagents such as formaldehyde or glutaraldehyde. The effect of various cross-linking parameters on the hardening effectiveness of SMMs containing peppermint oil was investigated. The optimum parameters were as follows: hardening for 6h at 15 degrees C and pH 6.0 with a TG concentration of 15 U/g gelatin. Compared with formaldehyde, TG exhibits similar microcapsule hardening effectiveness.
authors.affiliation: State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Wuxi 214112, Jiangsu, China.
authors.forename: Zhi-Jian
authors.initials: ZJ
authors.lastname: Dong
authors.forename: Shu-Qin
authors.initials: SQ
authors.lastname: Xia
authors.forename: Serenus
authors.initials: S
authors.lastname: Hua
authors.forename: Khizar
authors.initials: K
authors.lastname: Hayat
authors.forename: Xiao-Ming
authors.initials: XM
authors.lastname: Zhang
authors.forename: Shi-Ying
authors.initials: SY
authors.lastname: Xu
mesh_terms: D002214:Capsules; D003432:Cross-Linking Reagents; D005079:Excipients; D005557:Formaldehyde / Q000737:chemistry; D005780:Gelatin; D006170:Gum Arabic; D006863:Hydrogen-Ion Concentration; D036142:Mentha piperita; D010316:Particle Size; D010938:Plant Oils / Q000008:administration & dosage / Q000737:chemistry; D013696:Temperature; D011503:Transglutaminases / Q000737:chemistry*; D014280:Triglycerides / Q000737:chemistry; D014867:Water
chemical_list: D002214:Capsules; D003432:Cross-Linking Reagents; D005079:Excipients; D010938:Plant Oils; D014280:Triglycerides; D014867:Water; D005557:Formaldehyde; D006170:Gum Arabic; D005780:Gelatin; C015424:peppermint oil; D011503:Transglutaminases