Testicular carcinoma presenting as cutaneous nasal metastasis: case report and review of the literature.
Testicular choriocarcinoma is a highly malignant germ cell neoplasm, which metastasises to lungs, and brain. Spread to the skin, however, is rare, with only 11 cases reported to our knowledge. This is the second reported case of a skin metastasis of choriocarcinoma to the head and neck, and the third in which a cutaneous metastasis was the first finding at initial presentation. A review of published reports showed that it had been described as individual firm, reddish or violaceous subcutaneous nodules with typical histological features.
D000328:Adult; D002822:Choriocarcinoma / Q000737:chemistry / Q000556:secondary* / Q000601:surgery; D018997:Chorionic Gonadotropin, beta Subunit, Human / Q000032:analysis; D017809:Fatal Outcome; D006801:Humans; D008113:Liver Neoplasms / Q000556:secondary / Q000601:surgery; D008175:Lung Neoplasms / Q000556:secondary; D008297:Male; D009669:Nose Neoplasms / Q000737:chemistry / Q000556:secondary* / Q000601:surgery; D012186:Retroperitoneal Neoplasms / Q000556:secondary; D012878:Skin Neoplasms / Q000737:chemistry / Q000556:secondary* / Q000601:surgery; D013736:Testicular Neoplasms / Q000473:pathology* / Q000601:surgery
D018997:Chorionic Gonadotropin, beta Subunit, Human