title: [Biphenotypic Acute Leukemia with BCR-ABL mRNA Transcript b3a2 Type: A Case Report with Review of the Literature.].
abstract: Biphenotypic acute leukemia (BAL) is a subtype of leukemia of ambiguous lineage in the World Health Organization classification system. About one third of the cases have the Philadelphia chromosome, and some cases are associated with other structural abnormalities involving 11q23. BAL is known to have a poor prognosis in both children and adults. According to the previously reported BAL cases with positive BCR-ABL fusion gene, most of the BCR-ABL mRNA transcript type was e1a2. So, we describe here a 30-year-old adult BAL case with the karyotype 46,XY,t(9;22)(q34;q11.2) resulting in a very rare b3a2 type of BCR-ABL mRNA transcript.
authors.affiliation: Department of Laboratory Medicine, Chonnam National University Medical School and Chonnam National University Hwasun Hospital, Hwasun, Korea. mgshin@chonnam.ac.kr.
authors.forename: Hyun Woo
authors.initials: HW
authors.lastname: Choi
authors.forename: Myung Geun
authors.initials: MG
authors.lastname: Shin
authors.forename: Hyeoung Joon
authors.initials: HJ
authors.lastname: Kim
authors.forename: Il Kwon
authors.initials: IK
authors.lastname: Lee
authors.forename: Ju Hyun
authors.initials: JH
authors.lastname: Yun
authors.forename: Hye Ran
authors.initials: HR
authors.lastname: Kim
authors.forename: Yeo Kyeoung
authors.initials: YK
authors.lastname: Kim
authors.forename: Hyeong Kee
authors.initials: HK
authors.lastname: Yun
authors.forename: Duck
authors.initials: D
authors.lastname: Cho
authors.forename: Seung Jung
authors.initials: SJ
authors.lastname: Kee
authors.forename: Jong Hee
authors.initials: JH
authors.lastname: Shin
authors.forename: Soon Pal
authors.initials: SP
authors.lastname: Suh
authors.forename: Dong Wook
authors.initials: DW
authors.lastname: Ryang