title: Separation of amino acid enantiomers VIA chiral derivatization and non-chiral gas chromatography.
abstract: Two GC-MS methods for the enantioselective separation of the 20 proteinogenic amino acids are compared. Ethyl chloroformate and 2-chloropropanol were used to derivatize amino acid enantiomers. The diastereomers formed were separated on a non-chiral column by capillary gas chromatography. The separation performances were compared to those obtained when using non-chiral derivatization on a chiral column.
authors.affiliation: Centre de Biophysique Moléculaire, CNRS, rue Charles Sadron, 45071 Orléans Cedex 2, France. bertrand@cnrs-orleans.fr <bertrand@cnrs-orleans.fr>
authors.forename: Marylène
authors.initials: M
authors.lastname: Bertrand
authors.forename: Annie
authors.initials: A
authors.lastname: Chabin
authors.forename: André
authors.initials: A
authors.lastname: Brack
authors.forename: Frances
authors.initials: F
authors.lastname: Westall
mesh_terms: D000596:Amino Acids / Q000302:isolation & purification*; D008401:Gas Chromatography-Mass Spectrometry / Q000379:methods*; D013237:Stereoisomerism
chemical_list: D000596:Amino Acids