Alteration of myocardial characteristics and function in patients with obstructive sleep apnea.
The aim of the present study was to examine subclinical effect of the severity of obstructive sleep apnea (OSA) on myocardial structural changes and function using echocardiographic integrated backscatter and tissue Doppler imaging. Fifty patients with suspected OSA underwent overnight polysomnography and echocardiographic assessment. The myocardial reflectivity and mitral annular velocity were obtained as measures of subclinical myocardial disease. The OSA patients had lower annular velocity and higher myocardial reflectivity compared with non-OSA subjects, although global systolic function was similar. In conclusion, OSA can affect myocardial integrity as well as myocardial diastolic function.
D000704:Analysis of Variance; D004452:Echocardiography; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D008943:Mitral Valve / Q000473:pathology*; D009200:Myocardial Contraction / Q000502:physiology*; D017286:Polysomnography; D012720:Severity of Illness Index; D020181:Sleep Apnea, Obstructive / Q000000981:diagnostic imaging / Q000503:physiopathology*