Evaluation of mineral trioxide aggregate and calcium hydroxide cement as pulp-capping agents in human teeth.
This study evaluated the histomorphologic response of human dental pulps capped with mineral trioxide aggregate (MTA) and Ca(OH)2 cement (CH). Pulp exposures were performed on the occlusal floor of 40 human permanent premolars. After that, the pulp was capped either with CH or MTA and restored with composite resin. After 30 and 60 days, teeth were extracted and processed for histologic exam and categorized in a histologic score system. The data were subjected to Kruskal-Wallis and Conover tests (alpha = .05). All groups performed well in terms of hard tissue bridge formation, inflammatory response, and other pulpal findings. However, a lower response of CH30 was observed for the dentin bridge formation, when compared with MTA30 and MTA60 groups. Although the pulp healing with calcium hydroxide was slower than that of MTA, both materials were successful for pulp capping in human teeth.
D000293:Adolescent; D000328:Adult; D017607:Aluminum Compounds / Q000009:adverse effects / Q000627:therapeutic use*; D001641:Bicuspid / Q000187:drug effects / Q000473:pathology* / Q000601:surgery; D017610:Calcium Compounds / Q000009:adverse effects / Q000627:therapeutic use*; D002126:Calcium Hydroxide / Q000009:adverse effects / Q000627:therapeutic use*; D003782:Dental Pulp / Q000187:drug effects / Q000473:pathology; D003785:Dental Pulp Capping / Q000009:adverse effects / Q000379:methods*; D004338:Drug Combinations; D006801:Humans; D010087:Oxides / Q000009:adverse effects / Q000627:therapeutic use*; D012387:Root Canal Filling Materials / Q000009:adverse effects / Q000627:therapeutic use*; D017640:Silicates / Q000009:adverse effects / Q000627:therapeutic use*; D016037:Single-Blind Method; D018709:Statistics, Nonparametric; D013997:Time Factors
D017607:Aluminum Compounds; D017610:Calcium Compounds; D004338:Drug Combinations; D010087:Oxides; D012387:Root Canal Filling Materials; D017640:Silicates; C086631:mineral trioxide aggregate; D002126:Calcium Hydroxide