title: Laparoscopic repair of incisional hernia: Outcomes of 100 consecutive cases comprising 25 wall defects larger than 15 cm.
abstract: BACKGROUND
  Minimal access surgery for incisional hernia repair is still debated, especially for large and giant wall defects. This study was undertaken to analyze the results of the use of the laparoscopic technique in incisional hernias smaller and larger than 15 cm of diameter.
  
  
  METHODS
  From 2002 to 2007 a total of 100 patients with incisional hernia were operated on by laparoscopy and were included in this study. As much as 38 patients were obese, with a body mass index (BMI) > 30 kg/m(2). The mean follow-up span was 24 months (range = 2-58). The fascial defect was recurrent in 19 patients, in 13 after previous repair with mesh and in 6 after repair without mesh. The wall defect was larger than 15 cm in 25 patients and in 6 of them it was 20 cm or larger as measured from within the peritoneal cavity.
  
  
  RESULTS
  The mean operating time was 152 +/- 25 min (range = 45-275), and for defects larger than 15 cm it was 205 +/- 101 min (range = 85-540). Two patients with massive adhesions needed conversion to open surgery, one after an intraoperative injury of an intestinal loop. Postoperative complications occurred in 23 patients; local complications were 10. Pulmonary embolism caused death in one obese patient. Morbidity and hospital stay were similar in obese and nonobese patients and the differences were not statistically relevant (p > 0.05). The outcomes in patients with wall defects larger than 15 cm showed no significant difference with outcomes of the remaining patients with smaller defects (p > 0.05). Recurrence occurred in three cases, and in one case local infection led to removal of the mesh.
  
  
  CONCLUSIONS
  Minimal access procedures can provide good results in the repair of incisional hernia, even when the diameter is larger than 15 cm. Obesity is not a contraindication to laparoscopic repair. Further studies are expected to confirm these promising results.
authors.affiliation: Surgery and Videolaparoscopy Department, Niguarda Hospital, Milan, Piazza Ospedale Maggiore 3, 20162, Milano, Italy.
authors.forename: Giovanni Carlo
authors.initials: GC
authors.lastname: Ferrari
authors.forename: Angelo
authors.initials: A
authors.lastname: Miranda
authors.forename: Stefano
authors.initials: S
authors.lastname: Di Lernia
authors.forename: Fabio
authors.initials: F
authors.lastname: Sansonna
authors.forename: Carmelo
authors.initials: C
authors.lastname: Magistro
authors.forename: Dario
authors.initials: D
authors.lastname: Maggioni
authors.forename: Ildo
authors.initials: I
authors.lastname: Scandroglio
authors.forename: Andrea
authors.initials: A
authors.lastname: Costanzi
authors.forename: Maurizio
authors.initials: M
authors.lastname: Franzetti
authors.forename: Raffaele
authors.initials: R
authors.lastname: Pugliese
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005240:Feasibility Studies; D005260:Female; D005500:Follow-Up Studies; D046449:Hernia, Abdominal / Q000473:pathology / Q000601:surgery*; D006801:Humans; D007431:Intraoperative Complications; D010535:Laparoscopy / Q000009:adverse effects / Q000379:methods / Q000401:mortality; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D012008:Recurrence; D012189:Retrospective Studies; D016896:Treatment Outcome; D055815:Young Adult