title: Discordant results in Tc-99m tetrofosmin and Tc-99m sestamibi parathyroid scintigraphies.
abstract: Parathyroid scintigraphies have been used to detect pathological parathyroid glands either before as well as after the parathyroid resection surgery in patients with hyperparathyroidism. One of the most utilized techniques to perform the studies is the double-phase images with Tc-99m sestamibi, which has been shown to be very accurate in the localization of enlarged parathyroid glands. Similar to Tc-99m sestamibi, Tc-99m tetrofosmin is a radiopharmaceutical initially developed to perform myocardial perfusion study that has been used to perform parathyroid scintigraphies. Although most of the papers suggest that the overall sensitivities of both radiopharmaceuticals are similar, there are some papers questioning the accuracy of Tc-99m tetrofosmin to detect abnormal parathyroid glands. In the present article, we report a case with discordant results by both methods.
authors.affiliation: Fleury-Centro de Medicina Diagnóstica, Seção de Medicina Nuclear, Rua Cincinato Braga 282, São Paulo, SP. paulo.duarte@fleury.com.br
authors.forename: Paulo Schiavom
authors.initials: PS
authors.lastname: Duarte
authors.forename: Fernanda C
authors.initials: FC
authors.lastname: Domingues
authors.forename: Michele Santi
authors.initials: MS
authors.lastname: Costa
authors.forename: Cynthia
authors.initials: C
authors.lastname: Brandão
authors.forename: Marco A C de
authors.initials: MA
authors.lastname: Oliveira
authors.forename: José G H
authors.initials: JG
authors.lastname: Vieira
mesh_terms: D000368:Aged; D005260:Female; D006801:Humans; D009943:Organophosphorus Compounds; D015609:Organotechnetium Compounds; D010280:Parathyroid Glands / Q000000981:diagnostic imaging*; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals; D012680:Sensitivity and Specificity; D017256:Technetium Tc 99m Sestamibi
chemical_list: D009943:Organophosphorus Compounds; D015609:Organotechnetium Compounds; D019275:Radiopharmaceuticals; C078700:technetium tc-99m tetrofosmin; D017256:Technetium Tc 99m Sestamibi