title: The burden of rheumatoid arthritis and access to treatment: determinants of access.
abstract: As part of the study "The Burden of Rheumatoid Arthritis (RA) and Patient Access to Treatment", this paper reviews the impact on access to RA drugs of the approval processes, pricing and funding decisions and times to market (access) in different countries. In addition, an overview of health technology assessments (HTA) and the economic literature related to RA treatments is provided. The time from approval to market access ranged from immediate to over 500 days in the countries included in the study. A total of 55 HTA reports were identified, 40 of them in the period between 2002 and 2006; 29 were performed by European HTA agencies, 14 in Canada and 7 in the United States. A total of 239 economic evaluations related to RA were identified in a specialized health economic database (HEED).
authors.affiliation: i3/Innovus, Stockholm, Sweden. jonas.lundqvist@i3innovus.com
authors.forename: J
authors.initials: J
authors.lastname: Lundqvist
authors.forename: F
authors.initials: F
authors.lastname: Kastäng
authors.forename: G
authors.initials: G
authors.lastname: Kobelt
authors.forename: B
authors.initials: B
authors.lastname: Jönsson
mesh_terms: D018501:Antirheumatic Agents / Q000627:therapeutic use*; D001172:Arthritis, Rheumatoid / Q000188:drug therapy* / Q000191:economics; D020811:Biomedical Technology; D017281:Cost of Illness; D016208:Databases, Factual; D017277:Drug Approval; D016527:Drug Costs; D006297:Health Services Accessibility / Q000191:economics*; D006801:Humans; D008389:Marketing of Health Services; D013673:Technology Assessment, Biomedical
chemical_list: D018501:Antirheumatic Agents