title: Sleep disturbances in patients on maintenance hemodialysis: role of dialysis shift.
abstract: OBJECTIVE
  Subjective sleep complaints have been reported in up to 80% of patients with end stage renal disease (ESRD). In these patients, sleep disturbances manifesting as insomnia, sleep apnea syndrome, restless leg syndrome (RLS), periodic limb movement disorder and excessive daytime sleepiness (EDS) have been frequently reported. Moreover, studies about the role of dialysis shift on sleep abnormalities, morbidity and mortality are still scarce. The aim of this study was to investigate the influence of dialysis shift on the quality of sleep and sleep abnormalities in patients with ESRD.
  
  
  METHODS
  We studied one hundred consecutive patients from a dialysis center. Quality of sleep was assessed by the Pittsburgh Sleep Quality Index and subjective EDS by the Epworth Sleepiness Scale. Restless leg syndrome was diagnosed using the four minimum criteria defined by the International Restless Legs Syndrome Study Group. Clinical and laboratory parameters were obtained by interview and chart review. Adequacy of dialysis was evaluated by the Kt/V index.
  
  
  RESULTS
  Poor quality sleep (PSQI>6) was found in 75% of cases and was associated with RLS (p=0.004) and with snoring (p=0.016). EDS (ESS>10) was present in 28% of cases. Patients with EDS (1.33+/-0.29) had lower values of the Kt/v index (P=0.01) than those without EDS (1.52+/-0.32). RLS was present in 48% of cases. Irrespective of dialysis shift, poor quality sleep, EDS and RLS were not different among patients.
  
  
  CONCLUSIONS
  Poor quality sleep, EDS and RLS were common and not related to dialysis shift.
authors.affiliation: Medicine department, Federal University of Ceará, Fortaleza, CE, Brazil.
authors.forename: João Paulo Catunda
authors.initials: JP
authors.lastname: Bastos
authors.forename: Romualdo Barroso de
authors.initials: RB
authors.lastname: Sousa
authors.forename: Lara Albuquerque de Medeiros
authors.initials: LA
authors.lastname: Nepomuceno
authors.forename: Oswaldo A
authors.initials: OA
authors.lastname: Gutierrez-Adrianzen
authors.forename: Pedro Felipe Carvalhedo de
authors.initials: PF
authors.lastname: Bruin
authors.forename: Marx Lincoln Lima de Barros
authors.initials: ML
authors.lastname: Araújo
authors.forename: Veralice Meireles Sales de
authors.initials: VM
authors.lastname: Bruin
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002940:Circadian Rhythm; D004812:Epidemiologic Methods; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000150:complications / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D011788:Quality of Life; D006435:Renal Dialysis / Q000009:adverse effects; D012148:Restless Legs Syndrome / Q000175:diagnosis / Q000209:etiology; D012737:Sex Factors; D012890:Sleep / Q000502:physiology*; D012891:Sleep Apnea Syndromes / Q000175:diagnosis / Q000209:etiology; D007319:Sleep Initiation and Maintenance Disorders / Q000175:diagnosis / Q000209:etiology; D012893:Sleep Wake Disorders / Q000175:diagnosis* / Q000209:etiology; D012913:Snoring / Q000503:physiopathology; D013997:Time Factors