title: Severe rhabdomyolysis due to adipsic hypernatremia after craniopharyngioma surgery.
abstract: The association of diabetes insipidus and adipsia after craniopharyngioma surgery has high morbidity. Hypernatremia can be caused by adipsia and be aggravated by diabetes insipidus. Rhabdomyolysis rarely occurs.
  
  
  METHODS
  This is the first report of a diabetic patient with craniopharyngioma who developed diabetes insipidus and adipsia after surgery, evolving with severe hypernatremia that caused considerable rhabdomyolysis.
  
  
  CONCLUSIONS
  The importance of the evaluation of muscle integrity when under hypernatremic states is pointed out. Although adipsia may have a simple solution through volunteer water ingestion, serious consequences such as repeated severe hypernatremia episodes and intense rhabdomyolysis with high morbidity could occur, if adipsia is not diagnosed.
authors.affiliation: Endocrinology Division, Faculty of Medical Sciences, University of Campinas, Rua Tessália Vieira de Camargo 126, Campinas, SP. zantutw@fcm.unicamp.br
authors.forename: Denise E
authors.initials: DE
authors.lastname: Zantut-Wittmann
authors.forename: Heraldo Mendes
authors.initials: HM
authors.lastname: Garmes
authors.forename: Anita Denardo
authors.initials: AD
authors.lastname: Panzan
authors.forename: Marcelo de Oliveira
authors.initials: Mde O
authors.lastname: Lima
authors.forename: Maria Tereza Matias
authors.initials: MT
authors.lastname: Baptista
mesh_terms: D000281:Administration, Intranasal; D000328:Adult; D003397:Craniopharyngioma / Q000473:pathology / Q000601:surgery*; D003402:Creatine Kinase / Q000097:blood; D003681:Dehydration; D003919:Diabetes Insipidus / Q000209:etiology* / Q000628:therapy; D004326:Drinking; D006801:Humans; D006955:Hypernatremia / Q000209:etiology* / Q000628:therapy; D008297:Male; D010911:Pituitary Neoplasms / Q000473:pathology / Q000601:surgery*; D011183:Postoperative Complications / Q000628:therapy; D012206:Rhabdomyolysis / Q000209:etiology* / Q000628:therapy; D013894:Thirst
chemical_list: D003402:Creatine Kinase