Fragment-based ligand discovery meets phage display.
In a powerful complement to traditional ligand discovery methods such as high-throughput screening, fragment-based ligand discovery methods identify ligands piece by piece. A recent advance combines the concepts of fragment-based ligand discovery with phage-display technology to yield bivalent kinase inhibitors with high potency and specificity.
D008024:Ligands; D019151:Peptide Library; D047428:Protein Kinase Inhibitors / Q000737:chemistry
D008024:Ligands; D019151:Peptide Library; D047428:Protein Kinase Inhibitors