Granulocytic sarcoma of the lips: report of an unusual case.
Granulocytic sarcoma (GS) is a rare localized, extramedullary tumor composed of immature cells of granulocyte series. It is capable of marked local tissue destruction. This condition can be a precursor of acute myeloid leukaemia by months or years making its diagnosis critical. Its occurrence has been described in multiple sites including skin, lymph nodes, bone, and visceral organs. It is extremely rare in the oral cavity and only 30 cases have been reported in the literature to date and often as a lump in the gingiva, palate, and extraction sockets. We describe the first reported case of GS presenting as a solitary lump in the lip and review the pertinent literature.
D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D017809:Fatal Outcome; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000150:complications / Q000188:drug therapy; D008048:Lip Neoplasms / Q000150:complications / Q000473:pathology* / Q000628:therapy; D008297:Male; D009190:Myelodysplastic Syndromes / Q000150:complications; D009195:Peroxidase / Q000032:analysis; D023981:Sarcoma, Myeloid / Q000150:complications / Q000473:pathology* / Q000628:therapy
D009195:Peroxidase