title: Results in a consecutive series of 83 surgical corrections of symptomatic stenotic kinking of the internal carotid artery.
abstract: BACKGROUND
  Although there is a growing body of evidence to document the safety and efficacy of operative treatment of carotid stenosis, surgical indications for elongation and kinking of the internal carotid artery remain controversial. The goal of this study was to evaluate the efficacy of surgical correction of internal carotid artery kinking in patients with persistent hemispheric symptoms despite antiplatelet therapy.
  
  
  METHODS
  A consecutive series of 81 patients (mean age, 64 years) underwent 83 surgical procedures to correct kinking of the internal carotid artery either by shortening and reimplanting the vessel on the common carotid artery, inserting a bypass graft, or transposing the vessel onto the external carotid artery. Mean follow-up was 56 months (range, 15-135 months). Study endpoints were 30-day mortality and any stroke occurring during follow-up.
  
  
  RESULTS
  No postoperative death was observed. The postoperative stroke rate was 1%. Primary patency, freedom from neurologic symptoms, and late survival at 5 years (x +/- standard deviation) were 89 +/- 4.1%, 92 +/- 4%, and 71 +/- 6%, respectively.
  
  
  CONCLUSIONS
  The findings of this study indicate that surgical correction for symptomatic stenotic kinking of the internal carotid artery is safe and effective in relieving symptoms and preventing stroke. Operative correction should be considered as the standard treatment for patients with symptomatic carotid kinking that does not respond to antiplatelet therapy.
authors.affiliation: Francesco Durante Department of Surgery, La Sapienza University, Rome, Italy. giulio.illuminati@uniroma1.it
authors.forename: Giulio
authors.initials: G
authors.lastname: Illuminati
authors.forename: Jean-Baptiste
authors.initials: JB
authors.lastname: Ricco
authors.forename: Francesco G
authors.initials: FG
authors.lastname: Caliò
authors.forename: Antonio
authors.initials: A
authors.lastname: D'Urso
authors.forename: Gianluca
authors.initials: G
authors.lastname: Ceccanei
authors.forename: Francesco
authors.initials: F
authors.lastname: Vietri
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001807:Blood Vessel Prosthesis; D002343:Carotid Artery, Internal / Q000601:surgery*; D016893:Carotid Stenosis / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D053208:Kaplan-Meier Estimate; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D020521:Stroke / Q000453:epidemiology / Q000209:etiology; D016896:Treatment Outcome; D014654:Vascular Patency; D014656:Vascular Surgical Procedures / Q000009:adverse effects / Q000379:methods* / Q000592:standards