title: [Evaluation of fundus autofluorescence in hereditary retinal diseases using Heidelberg Retina Angiograph2].
abstract: OBJECTIVE
  To define characteristics of the fundus autofluorescence examination, verifying usefulness in the diagnosis and care of hereditary retinal diseases.
  
  
  METHODS
  28 patients, adults, divided equally into four groups with diagnoses of Stargardt macular dystrophy, cone dystrophy, retinitis pigmentosa and healthy volunteers for the establishment of the normality pattern. An average of nine images with the filter for fluorescein angiography was obtained for the formation of the image autofluorescence using Heidelberg Retina Angiograph2. The images of each group of patients were analyzed to verify common characteristics.
  
  
  RESULTS
  The fundus autofluorescence of healthy volunteers showed the foveal area darker than the surrounding retina. The images of Stargardt macular dystrophy, in general, presented an oval central lesion, with reduced autofluorescence. The main alterations of the autofluorescence in patients with cone dystrophy were reduced foveal autofluorescence with a parafoveal ring of increased autofluorescence. In general, the images of retinitis pigmentosa showed outlying pigments with reduced autofluorescence, and of the foveal area, in some cases disorganization or reduced autofluorescence.
  
  
  CONCLUSIONS
  The study showed the existence of patterns of fundus autofluorescence in the hereditary retinal diseases that allow the diagnosis and better interpretation of the pathogenesis of these diseases.
authors.affiliation: Curso de Tecnologia Oftálmica, Universidade Federal de São Paulo, São Paulo, SP, Brazil. mo_nique08@yahoo.com.br
authors.forename: Monique
authors.initials: M
authors.lastname: Côco
authors.forename: Natalia Tamie
authors.initials: NT
authors.lastname: Baba
authors.forename: Juliana Maria Ferraz
authors.initials: JM
authors.lastname: Sallum
mesh_terms: D000293:Adolescent; D000328:Adult; D016022:Case-Control Studies; D015785:Eye Diseases, Hereditary / Q000473:pathology*; D005260:Female; D005451:Fluorescein Angiography / Q000295:instrumentation*; D005453:Fluorescence; D005654:Fundus Oculi; D006801:Humans; D007089:Image Enhancement; D008062:Lipofuscin / Q000378:metabolism; D008268:Macular Degeneration / Q000473:pathology; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D017949:Retinal Cone Photoreceptor Cells / Q000473:pathology; D012164:Retinal Diseases / Q000235:genetics / Q000473:pathology*; D012174:Retinitis Pigmentosa / Q000473:pathology
chemical_list: D008062:Lipofuscin
vernacular_title: Avaliação da autofluorescência do fundo de olho nas distrofias de retina com o aparelho Heidelberg Retina Angiograph2.