title: Numerical study of the effects of scatterer sizes and distributions on multiple backscattered intensity patterns of polarized light.
abstract: We investigate numerically the effects of scatterer sizes on backscattered polarization patterns using the third-order scattering model developed. The calculated results show that both parallel and cross polarization patterns from water suspensions of polystyrene spheres have four-lobe structures of the azimuth dependence of intensities. Particularly, the parallel polarization pattern is sensitive to scatterer sizes, exhibiting good agreement with prior experimental measurements. Furthermore, the polarization patterns from the dysplastic and normal cells with different size distribution widths are calculated and analyzed. The results show that the polarization patterns of dysplastic and normal cells have distinct differences, which might be used for identification of the morphological structure changes of cancer, dysplasia, and regeneration cells.
authors.affiliation: Britton Chance Center for Biomedical Photonics, Wuhan National Laboratory for Optoelectronics, Huazhong University of Science and Technology, Wuhan 430074, China.
authors.forename: Yong
authors.initials: Y
authors.lastname: Deng
authors.forename: Shaoqun
authors.initials: S
authors.lastname: Zeng
authors.forename: Qingming
authors.initials: Q
authors.lastname: Luo
authors.forename: Zhihong
authors.initials: Z
authors.lastname: Zhang
authors.forename: Ling
authors.initials: L
authors.lastname: Fu
mesh_terms: D000465:Algorithms; D003198:Computer Simulation; D007089:Image Enhancement / Q000379:methods*; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D008027:Light; D008859:Microscopy, Polarization / Q000379:methods*; D008954:Models, Biological; D009716:Numerical Analysis, Computer-Assisted; D012031:Refractometry / Q000379:methods*; D015203:Reproducibility of Results; D012542:Scattering, Radiation; D012680:Sensitivity and Specificity