title: [Clinical treatment of diffuse unilateral subacute neuroretinitis with albendazole].
abstract: OBJECTIVE
  To describe the evolution of a series of cases of diffuse unilateral subacute neuroretinitis (DUSN) treated with albendazole.
  
  
  METHODS
  Interventional case series. The authors developed a non-randomized clinical trial protocol to investigate the clinical evolution of diffuse unilateral subacute neuroretinitis cases treated with albendazole. According to protocol criteria up to now, six patients were selected that will be described separately.
  
  
  RESULTS
  Of the six studied patients, four presented the worm. All six patients treated with the antiparasitic drug showed improvement of visual acuity and of chorioretinal scars. During the weeks of treatment, evidence of worm inactivation was documented for the four patients with visible worms. No adverse drug side effects were observed.
  
  
  CONCLUSIONS
  The antiparasitic drug albendazole seems to be beneficial and safe in patients with diffuse unilateral subacute neuroretinitis. More studies are necessary to evaluate the effectiveness of albendazole in the treatment of diffuse unilateral subacute neuroretinitis.
authors.affiliation: Programa de Pós-graduação Strictu-Sensu em Medicina e Ciências da Saúde, Universidade Estadual de Londrina, Londrina, PR, Brazil. marcus.malaguido@uol.com.br
authors.forename: Marcus Rudolph
authors.initials: MR
authors.lastname: Malaguido
authors.forename: Antonio Marcelo Barbante
authors.initials: AM
authors.lastname: Casella
authors.forename: Daniela Rossetto Garcia
authors.initials: DR
authors.lastname: Malaguido
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D015766:Albendazole / Q000008:administration & dosage / Q000627:therapeutic use*; D000977:Antiparasitic Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D002648:Child; D002825:Chorioretinitis / Q000188:drug therapy / Q000469:parasitology / Q000473:pathology; D015822:Eye Infections, Parasitic / Q000188:drug therapy* / Q000473:pathology; D005260:Female; D006801:Humans; D008297:Male; D012107:Research Design; D012173:Retinitis / Q000188:drug therapy* / Q000469:parasitology / Q000473:pathology; D012720:Severity of Illness Index; D013997:Time Factors; D016896:Treatment Outcome; D014792:Visual Acuity / Q000187:drug effects; D058609:Visual Field Tests
chemical_list: D000977:Antiparasitic Agents; D015766:Albendazole
vernacular_title: Tratamento clínico da neurorretinite subaguda difusa unilateral com albendazol.