title: The FLX gene of Arabidopsis is required for FRI-dependent activation of FLC expression.
abstract: The Arabidopsis FLOWERING LOCUS C (FLC) gene encodes a MADS box protein that acts as a dose-dependent repressor of flowering. Mutants and ecotypes with elevated expression of FLC are late flowering and vernalization responsive. In this study we describe an early flowering mutant in the C24 ecotype, flc expressor (flx), that has reduced expression of FLC. FLX encodes a protein of unknown function with putative leucine zipper domains. FLX is required for FRIGIDA (FRI)-mediated activation of FLC but not for activation of FLC in autonomous pathway mutants. FLX is also required for expression of the FLC paralogs MADS AFFECTING FLOWERING 1 (MAF1) and MAF2.
authors.affiliation: CSIRO Plant Industry, GPO Box 1600, Canberra ACT 2601, Australia.
authors.forename: Carol R
authors.initials: CR
authors.lastname: Andersson
authors.forename: Chris A
authors.initials: CA
authors.lastname: Helliwell
authors.forename: David J
authors.initials: DJ
authors.lastname: Bagnall
authors.forename: Trijntje P
authors.initials: TP
authors.lastname: Hughes
authors.forename: E Jean
authors.initials: EJ
authors.lastname: Finnegan
authors.forename: W James
authors.initials: WJ
authors.lastname: Peacock
authors.forename: Elizabeth S
authors.initials: ES
authors.lastname: Dennis
mesh_terms: D000595:Amino Acid Sequence; D017360:Arabidopsis / Q000235:genetics / Q000378:metabolism*; D029681:Arabidopsis Proteins / Q000235:genetics* / Q000378:metabolism*; D004269:DNA, Bacterial / Q000378:metabolism; D035264:Flowers / Q000378:metabolism; D018506:Gene Expression Regulation, Plant; D014644:Genetic Variation; D026161:MADS Domain Proteins / Q000235:genetics* / Q000378:metabolism*; D008969:Molecular Sequence Data; D009154:Mutation; D013997:Time Factors
chemical_list: D029681:Arabidopsis Proteins; D004269:DNA, Bacterial; C418902:At5g10140 protein, Arabidopsis; C529135:FLX protein, Arabidopsis; C414613:FRI protein, Arabidopsis; D026161:MADS Domain Proteins; C036483:T-DNA