title: Ten-year follow-up of laser in situ keratomileusis for myopia of up to -10 diopters.
abstract: OBJECTIVE
  To evaluate the long-term outcomes of laser in situ keratomileusis (LASIK) for myopia of up to -10 diopters (D).
  
  
  METHODS
  A long-term (10-year) follow-up retrospective, interventional case series.
  
  
  METHODS
  The study included 97 eyes of 70 patients with a preoperative spherical equivalent (SE) of up to -10 D treated with myopic LASIK at the Instituto Oftalmológico de Alicante, Alicante, Spain, using the VISX 20/20 excimer laser (Santa Clara, California, USA) and the Automated Corneal Shaper microkeratome (Chiron Vision, Irvine, California, USA). All patients were evaluated three months, one year, two years, five years, and 10 years after surgery. The main outcome measures were refractive predictability and stability, mean corneal keratometry, topographical cylinder, safety, efficacy, stability of visual acuity, and postoperative complications.
  
  
  RESULTS
  At 10 years, 71 (73%) of 97 eyes were within +/- 1.00 D and 89 (92%) were within +/- 2.00 D. Twenty eyes (20.8%) underwent retreatments because of overcorrection, undercorrection, regression, or both. The mean SE slightly decreased (myopic regression) over 10 years, with a mean myopic regression of -0.12 +/- 0.16 D per year. Fifty-four (54.6%) of 97 eyes demonstrated an increase in best spectacle-corrected visual acuity (BSCVA) after 10 years. No eye developed corneal ectasia in the long-term, and only three eyes lost more than two lines of BSCVA because of complications that were not attributable to the LASIK procedure.
  
  
  CONCLUSIONS
  LASIK for myopia of up to -10 D is a safe and effective procedure with slight myopic regression that slows down with time and a high rate of BSCVA increase in the long-term.
authors.affiliation: Vissum Department of Refractive Surgery and Division of Ophthalmology, Instituto Oftalmológico de Alicante, Miguel Hernandez University, Medical School, Alicante, Spain. jlalio@oftalio.om
authors.forename: Jorge L
authors.initials: JL
authors.lastname: Alió
authors.forename: Orkun
authors.initials: O
authors.lastname: Muftuoglu
authors.forename: Dolores
authors.initials: D
authors.lastname: Ortiz
authors.forename: Juan Jose
authors.initials: JJ
authors.lastname: Pérez-Santonja
authors.forename: Alberto
authors.initials: A
authors.lastname: Artola
authors.forename: Maria Jose
authors.initials: MJ
authors.lastname: Ayala
authors.forename: Maria Jose
authors.initials: MJ
authors.lastname: Garcia
authors.forename: Gracia Castro
authors.initials: GC
authors.lastname: de Luna
mesh_terms: D000293:Adolescent; D000328:Adult; D003315:Cornea / Q000503:physiopathology; D019781:Corneal Topography; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D020731:Keratomileusis, Laser In Situ; D054018:Lasers, Excimer; D008297:Male; D008875:Middle Aged; D009216:Myopia / Q000145:classification / Q000503:physiopathology / Q000601:surgery*; D011183:Postoperative Complications; D012029:Refraction, Ocular / Q000502:physiology; D012086:Reoperation; D012189:Retrospective Studies; D016896:Treatment Outcome; D014792:Visual Acuity / Q000502:physiology