title: Effect of social support on informed consent in older adults with Parkinson disease and their caregivers.
abstract: OBJECTIVE
  To evaluate the effects of social support on comprehension and recall of consent form information in a study of Parkinson disease patients and their caregivers.
  
  
  METHODS
  Comparison of comprehension and recall outcomes among participants who read and signed the consent form accompanied by a family member/friend versus those of participants who read and signed the consent form unaccompanied. Comprehension and recall of consent form information were measured at one week and one month respectively, using Part A of the Quality of Informed Consent Questionnaire (QuIC).
  
  
  RESULTS
  The mean age of the sample of 143 participants was 71 years (SD = 8.6 years). Analysis of covariance was used to compare QuIC scores between the intervention group (n = 70) and control group (n = 73). In the 1-week model, no statistically significant intervention effect was found (p = 0.860). However, the intervention status by patient status interaction was statistically significant (p = 0.012). In the 1-month model, no statistically significant intervention effect was found (p = 0.480). Again, however, the intervention status by patient status interaction was statistically significant (p = 0.040). At both time periods, intervention group patients scored higher (better) on the QuIC than did intervention group caregivers, and control group patients scored lower (worse) on the QuIC than did control group caregivers.
  
  
  CONCLUSIONS
  Social support played a significant role in enhancing comprehension and recall of consent form information among patients.
authors.affiliation: Department of Biostatistics, Bioinformatics, and Epidemiology, Medical University of South Carolina, Charleston, South Carolina 29425, USA. fordmar@musc.edu
authors.forename: M E
authors.initials: ME
authors.lastname: Ford
authors.forename: M
authors.initials: M
authors.lastname: Kallen
authors.forename: P
authors.initials: P
authors.lastname: Richardson
authors.forename: E
authors.initials: E
authors.lastname: Matthiesen
authors.forename: V
authors.initials: V
authors.lastname: Cox
authors.forename: E J
authors.initials: EJ
authors.lastname: Teng
authors.forename: K F
authors.initials: KF
authors.lastname: Cook
authors.forename: N J
authors.initials: NJ
authors.lastname: Petersen
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000704:Analysis of Variance; D017028:Caregivers; D032882:Comprehension; D032962:Consent Forms; D005260:Female; D006801:Humans; D007258:Informed Consent; D008297:Male; D011939:Mental Recall; D008875:Middle Aged; D010300:Parkinson Disease; D012944:Social Support