An adrenaline (and gold?) rush for the GPCR community.
G-Protein-coupled receptors are one of the largest protein families found in metazoans. Using several novel strategies, the first atomic resolution structures of a receptor that is activated by a diffusible ligand have been determined.
D018360:Crystallography, X-Ray; D004837:Epinephrine / Q000737:chemistry* / Q000378:metabolism*; D008958:Models, Molecular; D017434:Protein Structure, Tertiary; D043562:Receptors, G-Protein-Coupled / Q000737:chemistry* / Q000378:metabolism*
D043562:Receptors, G-Protein-Coupled; D004837:Epinephrine