[Metastatic process and therapies].
Tumor progression is now relatively well understood with changes at cellular and molecular levels. However mechanisms of the metastatic process are still not well elucidated. Several important questions remain unsolved to established new therapies. Moreover we need experimental animal models mimicking human metastatic disease to investigate and discover new targets for future therapies. These experimental approaches have to be coupled with pathological and clinical researches. Different experts will present the state of our knowledge in this domain.
D000818:Animals; D004195:Disease Models, Animal; D006801:Humans; D009362:Neoplasm Metastasis / Q000473:pathology / Q000503:physiopathology* / Q000628:therapy*; D011379:Prognosis
Mécanismes de la dissémination métastatique et ses thérapies. De la cellule normale aux cellules métastatiques.