Bladder and penile lesions with inguinal adenopathy after intravesical Bacillus Calmette-Guerin (BCG) treatment.
Intravesical Bacillus Calmette-Guerin (BCG) is usually a well-tolerated treatment strategy for transitional cell cancer of the bladder. We report a patient with penile and bladder mucosal lesions with inguinal adenopathy after six instillations of intravesical BCG. Pathology demonstrated inflammation with granulomatous changes. The lesions and adenopathy resolved with antituberculous drug treatment. We describe the patient's clinical presentation and review the complications of intravesical BCG treatment.
D000276:Adjuvants, Immunologic / Q000008:administration & dosage / Q000009:adverse effects*; D000283:Administration, Intravesical; D000368:Aged; D001500:BCG Vaccine / Q000008:administration & dosage / Q000009:adverse effects*; D002295:Carcinoma, Transitional Cell / Q000628:therapy*; D006099:Granuloma / Q000209:etiology; D006119:Groin; D006801:Humans; D008206:Lymphatic Diseases / Q000209:etiology*; D008297:Male; D010409:Penile Diseases / Q000209:etiology*; D001745:Urinary Bladder Diseases / Q000209:etiology*; D001749:Urinary Bladder Neoplasms / Q000628:therapy*
D000276:Adjuvants, Immunologic; D001500:BCG Vaccine