title: Successful heart transplantation following neonatal necrotic enterovirus myocarditis.
abstract: Enterovirus myocarditis is a potentially devastating diagnosis in the neonatal setting, with an associated high mortality and risk for chronically impaired cardiac function. Transplantation may be a possible therapeutic option, but, due to the comparative scarcity of the presentation, the limited donor pool, and fears of viral persistence and recurrence of myocarditis (especially in the immunocompromised, post-transplant setting), there are no reported cases in the literature. This case report illustrates an encouraging one-year outcome following heart transplantation for necrotic enterovirus myocarditis in a neonate.
authors.affiliation: Department of Paediatric Cardiology, Great Ormond Street Hospital for Children, Great Ormond Street, London, WC1N 3JH, UK. jacobsimmonds1@googlemail.com
authors.forename: Jacob
authors.initials: J
authors.lastname: Simmonds
authors.forename: David
authors.initials: D
authors.lastname: Cubitt
authors.forename: Michael
authors.initials: M
authors.lastname: Ashworth
authors.forename: Michael
authors.initials: M
authors.lastname: Burch
mesh_terms: D004770:Enterovirus; D004769:Enterovirus Infections / Q000150:complications*; D005260:Female; D016027:Heart Transplantation; D006801:Humans; D007231:Infant, Newborn; D009205:Myocarditis / Q000601:surgery* / Q000821:virology; D018487:Ventricular Dysfunction, Left / Q000821:virology*